data_9ET2
# 
_entry.id   9ET2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ET2         pdb_00009et2 10.2210/pdb9et2/pdb 
WWPDB D_1292137115 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ET2 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cyclin-dependent kinase 2'      34354.770 2   2.7.11.22 ? ? ? 
2 polymer     man Cyclin-A2                        30817.473 2   ?         ? ? ? 
3 non-polymer syn '~{N}-(4-bromophenyl)ethanamide' 214.059   4   ?         ? ? ? 
4 water       nat water                            18.015    394 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cell division protein kinase 2,p33 protein kinase' 
2 Cyclin-A                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
2 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
B,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 '~{N}-(4-bromophenyl)ethanamide' IJX 
4 water                            HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   SER n 
1 5   MET n 
1 6   GLU n 
1 7   ASN n 
1 8   PHE n 
1 9   GLN n 
1 10  LYS n 
1 11  VAL n 
1 12  GLU n 
1 13  LYS n 
1 14  ILE n 
1 15  GLY n 
1 16  GLU n 
1 17  GLY n 
1 18  THR n 
1 19  TYR n 
1 20  GLY n 
1 21  VAL n 
1 22  VAL n 
1 23  TYR n 
1 24  LYS n 
1 25  ALA n 
1 26  ARG n 
1 27  ASN n 
1 28  LYS n 
1 29  LEU n 
1 30  THR n 
1 31  GLY n 
1 32  GLU n 
1 33  VAL n 
1 34  VAL n 
1 35  ALA n 
1 36  LEU n 
1 37  LYS n 
1 38  LYS n 
1 39  ILE n 
1 40  ARG n 
1 41  LEU n 
1 42  ASP n 
1 43  THR n 
1 44  GLU n 
1 45  THR n 
1 46  GLU n 
1 47  GLY n 
1 48  VAL n 
1 49  PRO n 
1 50  SER n 
1 51  THR n 
1 52  ALA n 
1 53  ILE n 
1 54  ARG n 
1 55  GLU n 
1 56  ILE n 
1 57  SER n 
1 58  LEU n 
1 59  LEU n 
1 60  LYS n 
1 61  GLU n 
1 62  LEU n 
1 63  ASN n 
1 64  HIS n 
1 65  PRO n 
1 66  ASN n 
1 67  ILE n 
1 68  VAL n 
1 69  LYS n 
1 70  LEU n 
1 71  LEU n 
1 72  ASP n 
1 73  VAL n 
1 74  ILE n 
1 75  HIS n 
1 76  THR n 
1 77  GLU n 
1 78  ASN n 
1 79  LYS n 
1 80  LEU n 
1 81  TYR n 
1 82  LEU n 
1 83  VAL n 
1 84  PHE n 
1 85  GLU n 
1 86  PHE n 
1 87  LEU n 
1 88  HIS n 
1 89  GLN n 
1 90  ASP n 
1 91  LEU n 
1 92  LYS n 
1 93  LYS n 
1 94  PHE n 
1 95  MET n 
1 96  ASP n 
1 97  ALA n 
1 98  SER n 
1 99  ALA n 
1 100 LEU n 
1 101 THR n 
1 102 GLY n 
1 103 ILE n 
1 104 PRO n 
1 105 LEU n 
1 106 PRO n 
1 107 LEU n 
1 108 ILE n 
1 109 LYS n 
1 110 SER n 
1 111 TYR n 
1 112 LEU n 
1 113 PHE n 
1 114 GLN n 
1 115 LEU n 
1 116 LEU n 
1 117 GLN n 
1 118 GLY n 
1 119 LEU n 
1 120 ALA n 
1 121 PHE n 
1 122 CYS n 
1 123 HIS n 
1 124 SER n 
1 125 HIS n 
1 126 ARG n 
1 127 VAL n 
1 128 LEU n 
1 129 HIS n 
1 130 ARG n 
1 131 ASP n 
1 132 LEU n 
1 133 LYS n 
1 134 PRO n 
1 135 GLN n 
1 136 ASN n 
1 137 LEU n 
1 138 LEU n 
1 139 ILE n 
1 140 ASN n 
1 141 THR n 
1 142 GLU n 
1 143 GLY n 
1 144 ALA n 
1 145 ILE n 
1 146 LYS n 
1 147 LEU n 
1 148 ALA n 
1 149 ASP n 
1 150 PHE n 
1 151 GLY n 
1 152 LEU n 
1 153 ALA n 
1 154 ARG n 
1 155 ALA n 
1 156 PHE n 
1 157 GLY n 
1 158 VAL n 
1 159 PRO n 
1 160 VAL n 
1 161 ARG n 
1 162 THR n 
1 163 TYR n 
1 164 TPO n 
1 165 HIS n 
1 166 GLU n 
1 167 VAL n 
1 168 VAL n 
1 169 THR n 
1 170 LEU n 
1 171 TRP n 
1 172 TYR n 
1 173 ARG n 
1 174 ALA n 
1 175 PRO n 
1 176 GLU n 
1 177 ILE n 
1 178 LEU n 
1 179 LEU n 
1 180 GLY n 
1 181 CYS n 
1 182 LYS n 
1 183 TYR n 
1 184 TYR n 
1 185 SER n 
1 186 THR n 
1 187 ALA n 
1 188 VAL n 
1 189 ASP n 
1 190 ILE n 
1 191 TRP n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 CYS n 
1 196 ILE n 
1 197 PHE n 
1 198 ALA n 
1 199 GLU n 
1 200 MET n 
1 201 VAL n 
1 202 THR n 
1 203 ARG n 
1 204 ARG n 
1 205 ALA n 
1 206 LEU n 
1 207 PHE n 
1 208 PRO n 
1 209 GLY n 
1 210 ASP n 
1 211 SER n 
1 212 GLU n 
1 213 ILE n 
1 214 ASP n 
1 215 GLN n 
1 216 LEU n 
1 217 PHE n 
1 218 ARG n 
1 219 ILE n 
1 220 PHE n 
1 221 ARG n 
1 222 THR n 
1 223 LEU n 
1 224 GLY n 
1 225 THR n 
1 226 PRO n 
1 227 ASP n 
1 228 GLU n 
1 229 VAL n 
1 230 VAL n 
1 231 TRP n 
1 232 PRO n 
1 233 GLY n 
1 234 VAL n 
1 235 THR n 
1 236 SER n 
1 237 MET n 
1 238 PRO n 
1 239 ASP n 
1 240 TYR n 
1 241 LYS n 
1 242 PRO n 
1 243 SER n 
1 244 PHE n 
1 245 PRO n 
1 246 LYS n 
1 247 TRP n 
1 248 ALA n 
1 249 ARG n 
1 250 GLN n 
1 251 ASP n 
1 252 PHE n 
1 253 SER n 
1 254 LYS n 
1 255 VAL n 
1 256 VAL n 
1 257 PRO n 
1 258 PRO n 
1 259 LEU n 
1 260 ASP n 
1 261 GLU n 
1 262 ASP n 
1 263 GLY n 
1 264 ARG n 
1 265 SER n 
1 266 LEU n 
1 267 LEU n 
1 268 SER n 
1 269 GLN n 
1 270 MET n 
1 271 LEU n 
1 272 HIS n 
1 273 TYR n 
1 274 ASP n 
1 275 PRO n 
1 276 ASN n 
1 277 LYS n 
1 278 ARG n 
1 279 ILE n 
1 280 SER n 
1 281 ALA n 
1 282 LYS n 
1 283 ALA n 
1 284 ALA n 
1 285 LEU n 
1 286 ALA n 
1 287 HIS n 
1 288 PRO n 
1 289 PHE n 
1 290 PHE n 
1 291 GLN n 
1 292 ASP n 
1 293 VAL n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 VAL n 
1 298 PRO n 
1 299 HIS n 
1 300 LEU n 
1 301 ARG n 
1 302 LEU n 
2 1   GLY n 
2 2   VAL n 
2 3   ASN n 
2 4   GLU n 
2 5   VAL n 
2 6   PRO n 
2 7   ASP n 
2 8   TYR n 
2 9   HIS n 
2 10  GLU n 
2 11  ASP n 
2 12  ILE n 
2 13  HIS n 
2 14  THR n 
2 15  TYR n 
2 16  LEU n 
2 17  ARG n 
2 18  GLU n 
2 19  MET n 
2 20  GLU n 
2 21  VAL n 
2 22  LYS n 
2 23  CYS n 
2 24  LYS n 
2 25  PRO n 
2 26  LYS n 
2 27  VAL n 
2 28  GLY n 
2 29  TYR n 
2 30  MET n 
2 31  LYS n 
2 32  LYS n 
2 33  GLN n 
2 34  PRO n 
2 35  ASP n 
2 36  ILE n 
2 37  THR n 
2 38  ASN n 
2 39  SER n 
2 40  MET n 
2 41  ARG n 
2 42  ALA n 
2 43  ILE n 
2 44  LEU n 
2 45  VAL n 
2 46  ASP n 
2 47  TRP n 
2 48  LEU n 
2 49  VAL n 
2 50  GLU n 
2 51  VAL n 
2 52  GLY n 
2 53  GLU n 
2 54  GLU n 
2 55  TYR n 
2 56  LYS n 
2 57  LEU n 
2 58  GLN n 
2 59  ASN n 
2 60  GLU n 
2 61  THR n 
2 62  LEU n 
2 63  HIS n 
2 64  LEU n 
2 65  ALA n 
2 66  VAL n 
2 67  ASN n 
2 68  TYR n 
2 69  ILE n 
2 70  ASP n 
2 71  ARG n 
2 72  PHE n 
2 73  LEU n 
2 74  SER n 
2 75  SER n 
2 76  MET n 
2 77  SER n 
2 78  VAL n 
2 79  LEU n 
2 80  ARG n 
2 81  GLY n 
2 82  LYS n 
2 83  LEU n 
2 84  GLN n 
2 85  LEU n 
2 86  VAL n 
2 87  GLY n 
2 88  THR n 
2 89  ALA n 
2 90  ALA n 
2 91  MET n 
2 92  LEU n 
2 93  LEU n 
2 94  ALA n 
2 95  SER n 
2 96  LYS n 
2 97  PHE n 
2 98  GLU n 
2 99  GLU n 
2 100 ILE n 
2 101 TYR n 
2 102 PRO n 
2 103 PRO n 
2 104 GLU n 
2 105 VAL n 
2 106 ALA n 
2 107 GLU n 
2 108 PHE n 
2 109 VAL n 
2 110 TYR n 
2 111 ILE n 
2 112 THR n 
2 113 ASP n 
2 114 ASP n 
2 115 THR n 
2 116 TYR n 
2 117 THR n 
2 118 LYS n 
2 119 LYS n 
2 120 GLN n 
2 121 VAL n 
2 122 LEU n 
2 123 ARG n 
2 124 MET n 
2 125 GLU n 
2 126 HIS n 
2 127 LEU n 
2 128 VAL n 
2 129 LEU n 
2 130 LYS n 
2 131 VAL n 
2 132 LEU n 
2 133 ALA n 
2 134 PHE n 
2 135 ASP n 
2 136 LEU n 
2 137 ALA n 
2 138 ALA n 
2 139 PRO n 
2 140 THR n 
2 141 ILE n 
2 142 ASN n 
2 143 GLN n 
2 144 PHE n 
2 145 LEU n 
2 146 THR n 
2 147 GLN n 
2 148 TYR n 
2 149 PHE n 
2 150 LEU n 
2 151 HIS n 
2 152 GLN n 
2 153 GLN n 
2 154 PRO n 
2 155 ALA n 
2 156 ASN n 
2 157 CYS n 
2 158 LYS n 
2 159 VAL n 
2 160 GLU n 
2 161 SER n 
2 162 LEU n 
2 163 ALA n 
2 164 MET n 
2 165 PHE n 
2 166 LEU n 
2 167 GLY n 
2 168 GLU n 
2 169 LEU n 
2 170 SER n 
2 171 LEU n 
2 172 ILE n 
2 173 ASP n 
2 174 ALA n 
2 175 ASP n 
2 176 PRO n 
2 177 TYR n 
2 178 LEU n 
2 179 LYS n 
2 180 TYR n 
2 181 LEU n 
2 182 PRO n 
2 183 SER n 
2 184 VAL n 
2 185 ILE n 
2 186 ALA n 
2 187 ALA n 
2 188 ALA n 
2 189 ALA n 
2 190 PHE n 
2 191 HIS n 
2 192 LEU n 
2 193 ALA n 
2 194 LEU n 
2 195 TYR n 
2 196 THR n 
2 197 VAL n 
2 198 THR n 
2 199 GLY n 
2 200 GLN n 
2 201 SER n 
2 202 TRP n 
2 203 PRO n 
2 204 GLU n 
2 205 SER n 
2 206 LEU n 
2 207 VAL n 
2 208 GLN n 
2 209 LYS n 
2 210 THR n 
2 211 GLY n 
2 212 TYR n 
2 213 THR n 
2 214 LEU n 
2 215 GLU n 
2 216 THR n 
2 217 LEU n 
2 218 LYS n 
2 219 PRO n 
2 220 CYS n 
2 221 LEU n 
2 222 LEU n 
2 223 ASP n 
2 224 LEU n 
2 225 HIS n 
2 226 GLN n 
2 227 THR n 
2 228 TYR n 
2 229 LEU n 
2 230 ARG n 
2 231 ALA n 
2 232 PRO n 
2 233 GLN n 
2 234 HIS n 
2 235 ALA n 
2 236 GLN n 
2 237 GLN n 
2 238 SER n 
2 239 ILE n 
2 240 ARG n 
2 241 GLU n 
2 242 LYS n 
2 243 TYR n 
2 244 LYS n 
2 245 ASN n 
2 246 SER n 
2 247 LYS n 
2 248 TYR n 
2 249 HIS n 
2 250 GLY n 
2 251 VAL n 
2 252 SER n 
2 253 LEU n 
2 254 LEU n 
2 255 ASN n 
2 256 PRO n 
2 257 PRO n 
2 258 GLU n 
2 259 THR n 
2 260 LEU n 
2 261 ASN n 
2 262 VAL n 
2 263 HIS n 
2 264 HIS n 
2 265 HIS n 
2 266 HIS n 
2 267 HIS n 
2 268 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
2 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                          ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                         ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                       ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                  ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                         ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                        ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                  ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                          ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                        ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                            ?                  'H2 O'           18.015  
IJX non-polymer         . '~{N}-(4-bromophenyl)ethanamide' ?                  'C8 H8 Br N O'   214.059 
ILE 'L-peptide linking' y ISOLEUCINE                       ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                          ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                           ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                       ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                    ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                          ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                           ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                        ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE                 PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN                       ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                         ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                           ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -3  -3  GLY GLY A . n 
A 1 2   PRO 2   -2  -2  PRO PRO A . n 
A 1 3   GLY 3   -1  -1  GLY GLY A . n 
A 1 4   SER 4   0   0   SER SER A . n 
A 1 5   MET 5   1   1   MET MET A . n 
A 1 6   GLU 6   2   2   GLU GLU A . n 
A 1 7   ASN 7   3   3   ASN ASN A . n 
A 1 8   PHE 8   4   4   PHE PHE A . n 
A 1 9   GLN 9   5   5   GLN GLN A . n 
A 1 10  LYS 10  6   6   LYS LYS A . n 
A 1 11  VAL 11  7   7   VAL VAL A . n 
A 1 12  GLU 12  8   8   GLU GLU A . n 
A 1 13  LYS 13  9   9   LYS LYS A . n 
A 1 14  ILE 14  10  10  ILE ILE A . n 
A 1 15  GLY 15  11  11  GLY GLY A . n 
A 1 16  GLU 16  12  12  GLU GLU A . n 
A 1 17  GLY 17  13  13  GLY GLY A . n 
A 1 18  THR 18  14  14  THR THR A . n 
A 1 19  TYR 19  15  15  TYR TYR A . n 
A 1 20  GLY 20  16  16  GLY GLY A . n 
A 1 21  VAL 21  17  17  VAL VAL A . n 
A 1 22  VAL 22  18  18  VAL VAL A . n 
A 1 23  TYR 23  19  19  TYR TYR A . n 
A 1 24  LYS 24  20  20  LYS LYS A . n 
A 1 25  ALA 25  21  21  ALA ALA A . n 
A 1 26  ARG 26  22  22  ARG ARG A . n 
A 1 27  ASN 27  23  23  ASN ASN A . n 
A 1 28  LYS 28  24  24  LYS LYS A . n 
A 1 29  LEU 29  25  25  LEU LEU A . n 
A 1 30  THR 30  26  26  THR THR A . n 
A 1 31  GLY 31  27  27  GLY GLY A . n 
A 1 32  GLU 32  28  28  GLU GLU A . n 
A 1 33  VAL 33  29  29  VAL VAL A . n 
A 1 34  VAL 34  30  30  VAL VAL A . n 
A 1 35  ALA 35  31  31  ALA ALA A . n 
A 1 36  LEU 36  32  32  LEU LEU A . n 
A 1 37  LYS 37  33  33  LYS LYS A . n 
A 1 38  LYS 38  34  34  LYS LYS A . n 
A 1 39  ILE 39  35  35  ILE ILE A . n 
A 1 40  ARG 40  36  36  ARG ARG A . n 
A 1 41  LEU 41  37  37  LEU LEU A . n 
A 1 42  ASP 42  38  38  ASP ASP A . n 
A 1 43  THR 43  39  39  THR THR A . n 
A 1 44  GLU 44  40  40  GLU GLU A . n 
A 1 45  THR 45  41  41  THR THR A . n 
A 1 46  GLU 46  42  42  GLU GLU A . n 
A 1 47  GLY 47  43  43  GLY GLY A . n 
A 1 48  VAL 48  44  44  VAL VAL A . n 
A 1 49  PRO 49  45  45  PRO PRO A . n 
A 1 50  SER 50  46  46  SER SER A . n 
A 1 51  THR 51  47  47  THR THR A . n 
A 1 52  ALA 52  48  48  ALA ALA A . n 
A 1 53  ILE 53  49  49  ILE ILE A . n 
A 1 54  ARG 54  50  50  ARG ARG A . n 
A 1 55  GLU 55  51  51  GLU GLU A . n 
A 1 56  ILE 56  52  52  ILE ILE A . n 
A 1 57  SER 57  53  53  SER SER A . n 
A 1 58  LEU 58  54  54  LEU LEU A . n 
A 1 59  LEU 59  55  55  LEU LEU A . n 
A 1 60  LYS 60  56  56  LYS LYS A . n 
A 1 61  GLU 61  57  57  GLU GLU A . n 
A 1 62  LEU 62  58  58  LEU LEU A . n 
A 1 63  ASN 63  59  59  ASN ASN A . n 
A 1 64  HIS 64  60  60  HIS HIS A . n 
A 1 65  PRO 65  61  61  PRO PRO A . n 
A 1 66  ASN 66  62  62  ASN ASN A . n 
A 1 67  ILE 67  63  63  ILE ILE A . n 
A 1 68  VAL 68  64  64  VAL VAL A . n 
A 1 69  LYS 69  65  65  LYS LYS A . n 
A 1 70  LEU 70  66  66  LEU LEU A . n 
A 1 71  LEU 71  67  67  LEU LEU A . n 
A 1 72  ASP 72  68  68  ASP ASP A . n 
A 1 73  VAL 73  69  69  VAL VAL A . n 
A 1 74  ILE 74  70  70  ILE ILE A . n 
A 1 75  HIS 75  71  71  HIS HIS A . n 
A 1 76  THR 76  72  72  THR THR A . n 
A 1 77  GLU 77  73  73  GLU GLU A . n 
A 1 78  ASN 78  74  74  ASN ASN A . n 
A 1 79  LYS 79  75  75  LYS LYS A . n 
A 1 80  LEU 80  76  76  LEU LEU A . n 
A 1 81  TYR 81  77  77  TYR TYR A . n 
A 1 82  LEU 82  78  78  LEU LEU A . n 
A 1 83  VAL 83  79  79  VAL VAL A . n 
A 1 84  PHE 84  80  80  PHE PHE A . n 
A 1 85  GLU 85  81  81  GLU GLU A . n 
A 1 86  PHE 86  82  82  PHE PHE A . n 
A 1 87  LEU 87  83  83  LEU LEU A . n 
A 1 88  HIS 88  84  84  HIS HIS A . n 
A 1 89  GLN 89  85  85  GLN GLN A . n 
A 1 90  ASP 90  86  86  ASP ASP A . n 
A 1 91  LEU 91  87  87  LEU LEU A . n 
A 1 92  LYS 92  88  88  LYS LYS A . n 
A 1 93  LYS 93  89  89  LYS LYS A . n 
A 1 94  PHE 94  90  90  PHE PHE A . n 
A 1 95  MET 95  91  91  MET MET A . n 
A 1 96  ASP 96  92  92  ASP ASP A . n 
A 1 97  ALA 97  93  93  ALA ALA A . n 
A 1 98  SER 98  94  94  SER SER A . n 
A 1 99  ALA 99  95  95  ALA ALA A . n 
A 1 100 LEU 100 96  96  LEU LEU A . n 
A 1 101 THR 101 97  97  THR THR A . n 
A 1 102 GLY 102 98  98  GLY GLY A . n 
A 1 103 ILE 103 99  99  ILE ILE A . n 
A 1 104 PRO 104 100 100 PRO PRO A . n 
A 1 105 LEU 105 101 101 LEU LEU A . n 
A 1 106 PRO 106 102 102 PRO PRO A . n 
A 1 107 LEU 107 103 103 LEU LEU A . n 
A 1 108 ILE 108 104 104 ILE ILE A . n 
A 1 109 LYS 109 105 105 LYS LYS A . n 
A 1 110 SER 110 106 106 SER SER A . n 
A 1 111 TYR 111 107 107 TYR TYR A . n 
A 1 112 LEU 112 108 108 LEU LEU A . n 
A 1 113 PHE 113 109 109 PHE PHE A . n 
A 1 114 GLN 114 110 110 GLN GLN A . n 
A 1 115 LEU 115 111 111 LEU LEU A . n 
A 1 116 LEU 116 112 112 LEU LEU A . n 
A 1 117 GLN 117 113 113 GLN GLN A . n 
A 1 118 GLY 118 114 114 GLY GLY A . n 
A 1 119 LEU 119 115 115 LEU LEU A . n 
A 1 120 ALA 120 116 116 ALA ALA A . n 
A 1 121 PHE 121 117 117 PHE PHE A . n 
A 1 122 CYS 122 118 118 CYS CYS A . n 
A 1 123 HIS 123 119 119 HIS HIS A . n 
A 1 124 SER 124 120 120 SER SER A . n 
A 1 125 HIS 125 121 121 HIS HIS A . n 
A 1 126 ARG 126 122 122 ARG ARG A . n 
A 1 127 VAL 127 123 123 VAL VAL A . n 
A 1 128 LEU 128 124 124 LEU LEU A . n 
A 1 129 HIS 129 125 125 HIS HIS A . n 
A 1 130 ARG 130 126 126 ARG ARG A . n 
A 1 131 ASP 131 127 127 ASP ASP A . n 
A 1 132 LEU 132 128 128 LEU LEU A . n 
A 1 133 LYS 133 129 129 LYS LYS A . n 
A 1 134 PRO 134 130 130 PRO PRO A . n 
A 1 135 GLN 135 131 131 GLN GLN A . n 
A 1 136 ASN 136 132 132 ASN ASN A . n 
A 1 137 LEU 137 133 133 LEU LEU A . n 
A 1 138 LEU 138 134 134 LEU LEU A . n 
A 1 139 ILE 139 135 135 ILE ILE A . n 
A 1 140 ASN 140 136 136 ASN ASN A . n 
A 1 141 THR 141 137 137 THR THR A . n 
A 1 142 GLU 142 138 138 GLU GLU A . n 
A 1 143 GLY 143 139 139 GLY GLY A . n 
A 1 144 ALA 144 140 140 ALA ALA A . n 
A 1 145 ILE 145 141 141 ILE ILE A . n 
A 1 146 LYS 146 142 142 LYS LYS A . n 
A 1 147 LEU 147 143 143 LEU LEU A . n 
A 1 148 ALA 148 144 144 ALA ALA A . n 
A 1 149 ASP 149 145 145 ASP ASP A . n 
A 1 150 PHE 150 146 146 PHE PHE A . n 
A 1 151 GLY 151 147 147 GLY GLY A . n 
A 1 152 LEU 152 148 148 LEU LEU A . n 
A 1 153 ALA 153 149 149 ALA ALA A . n 
A 1 154 ARG 154 150 150 ARG ARG A . n 
A 1 155 ALA 155 151 151 ALA ALA A . n 
A 1 156 PHE 156 152 152 PHE PHE A . n 
A 1 157 GLY 157 153 153 GLY GLY A . n 
A 1 158 VAL 158 154 154 VAL VAL A . n 
A 1 159 PRO 159 155 155 PRO PRO A . n 
A 1 160 VAL 160 156 156 VAL VAL A . n 
A 1 161 ARG 161 157 157 ARG ARG A . n 
A 1 162 THR 162 158 158 THR THR A . n 
A 1 163 TYR 163 159 159 TYR TYR A . n 
A 1 164 TPO 164 160 160 TPO TPO A . n 
A 1 165 HIS 165 161 161 HIS HIS A . n 
A 1 166 GLU 166 162 162 GLU GLU A . n 
A 1 167 VAL 167 163 163 VAL VAL A . n 
A 1 168 VAL 168 164 164 VAL VAL A . n 
A 1 169 THR 169 165 165 THR THR A . n 
A 1 170 LEU 170 166 166 LEU LEU A . n 
A 1 171 TRP 171 167 167 TRP TRP A . n 
A 1 172 TYR 172 168 168 TYR TYR A . n 
A 1 173 ARG 173 169 169 ARG ARG A . n 
A 1 174 ALA 174 170 170 ALA ALA A . n 
A 1 175 PRO 175 171 171 PRO PRO A . n 
A 1 176 GLU 176 172 172 GLU GLU A . n 
A 1 177 ILE 177 173 173 ILE ILE A . n 
A 1 178 LEU 178 174 174 LEU LEU A . n 
A 1 179 LEU 179 175 175 LEU LEU A . n 
A 1 180 GLY 180 176 176 GLY GLY A . n 
A 1 181 CYS 181 177 177 CYS CYS A . n 
A 1 182 LYS 182 178 178 LYS LYS A . n 
A 1 183 TYR 183 179 179 TYR TYR A . n 
A 1 184 TYR 184 180 180 TYR TYR A . n 
A 1 185 SER 185 181 181 SER SER A . n 
A 1 186 THR 186 182 182 THR THR A . n 
A 1 187 ALA 187 183 183 ALA ALA A . n 
A 1 188 VAL 188 184 184 VAL VAL A . n 
A 1 189 ASP 189 185 185 ASP ASP A . n 
A 1 190 ILE 190 186 186 ILE ILE A . n 
A 1 191 TRP 191 187 187 TRP TRP A . n 
A 1 192 SER 192 188 188 SER SER A . n 
A 1 193 LEU 193 189 189 LEU LEU A . n 
A 1 194 GLY 194 190 190 GLY GLY A . n 
A 1 195 CYS 195 191 191 CYS CYS A . n 
A 1 196 ILE 196 192 192 ILE ILE A . n 
A 1 197 PHE 197 193 193 PHE PHE A . n 
A 1 198 ALA 198 194 194 ALA ALA A . n 
A 1 199 GLU 199 195 195 GLU GLU A . n 
A 1 200 MET 200 196 196 MET MET A . n 
A 1 201 VAL 201 197 197 VAL VAL A . n 
A 1 202 THR 202 198 198 THR THR A . n 
A 1 203 ARG 203 199 199 ARG ARG A . n 
A 1 204 ARG 204 200 200 ARG ARG A . n 
A 1 205 ALA 205 201 201 ALA ALA A . n 
A 1 206 LEU 206 202 202 LEU LEU A . n 
A 1 207 PHE 207 203 203 PHE PHE A . n 
A 1 208 PRO 208 204 204 PRO PRO A . n 
A 1 209 GLY 209 205 205 GLY GLY A . n 
A 1 210 ASP 210 206 206 ASP ASP A . n 
A 1 211 SER 211 207 207 SER SER A . n 
A 1 212 GLU 212 208 208 GLU GLU A . n 
A 1 213 ILE 213 209 209 ILE ILE A . n 
A 1 214 ASP 214 210 210 ASP ASP A . n 
A 1 215 GLN 215 211 211 GLN GLN A . n 
A 1 216 LEU 216 212 212 LEU LEU A . n 
A 1 217 PHE 217 213 213 PHE PHE A . n 
A 1 218 ARG 218 214 214 ARG ARG A . n 
A 1 219 ILE 219 215 215 ILE ILE A . n 
A 1 220 PHE 220 216 216 PHE PHE A . n 
A 1 221 ARG 221 217 217 ARG ARG A . n 
A 1 222 THR 222 218 218 THR THR A . n 
A 1 223 LEU 223 219 219 LEU LEU A . n 
A 1 224 GLY 224 220 220 GLY GLY A . n 
A 1 225 THR 225 221 221 THR THR A . n 
A 1 226 PRO 226 222 222 PRO PRO A . n 
A 1 227 ASP 227 223 223 ASP ASP A . n 
A 1 228 GLU 228 224 224 GLU GLU A . n 
A 1 229 VAL 229 225 225 VAL VAL A . n 
A 1 230 VAL 230 226 226 VAL VAL A . n 
A 1 231 TRP 231 227 227 TRP TRP A . n 
A 1 232 PRO 232 228 228 PRO PRO A . n 
A 1 233 GLY 233 229 229 GLY GLY A . n 
A 1 234 VAL 234 230 230 VAL VAL A . n 
A 1 235 THR 235 231 231 THR THR A . n 
A 1 236 SER 236 232 232 SER SER A . n 
A 1 237 MET 237 233 233 MET MET A . n 
A 1 238 PRO 238 234 234 PRO PRO A . n 
A 1 239 ASP 239 235 235 ASP ASP A . n 
A 1 240 TYR 240 236 236 TYR TYR A . n 
A 1 241 LYS 241 237 237 LYS LYS A . n 
A 1 242 PRO 242 238 238 PRO PRO A . n 
A 1 243 SER 243 239 239 SER SER A . n 
A 1 244 PHE 244 240 240 PHE PHE A . n 
A 1 245 PRO 245 241 241 PRO PRO A . n 
A 1 246 LYS 246 242 242 LYS LYS A . n 
A 1 247 TRP 247 243 243 TRP TRP A . n 
A 1 248 ALA 248 244 244 ALA ALA A . n 
A 1 249 ARG 249 245 245 ARG ARG A . n 
A 1 250 GLN 250 246 246 GLN GLN A . n 
A 1 251 ASP 251 247 247 ASP ASP A . n 
A 1 252 PHE 252 248 248 PHE PHE A . n 
A 1 253 SER 253 249 249 SER SER A . n 
A 1 254 LYS 254 250 250 LYS LYS A . n 
A 1 255 VAL 255 251 251 VAL VAL A . n 
A 1 256 VAL 256 252 252 VAL VAL A . n 
A 1 257 PRO 257 253 253 PRO PRO A . n 
A 1 258 PRO 258 254 254 PRO PRO A . n 
A 1 259 LEU 259 255 255 LEU LEU A . n 
A 1 260 ASP 260 256 256 ASP ASP A . n 
A 1 261 GLU 261 257 257 GLU GLU A . n 
A 1 262 ASP 262 258 258 ASP ASP A . n 
A 1 263 GLY 263 259 259 GLY GLY A . n 
A 1 264 ARG 264 260 260 ARG ARG A . n 
A 1 265 SER 265 261 261 SER SER A . n 
A 1 266 LEU 266 262 262 LEU LEU A . n 
A 1 267 LEU 267 263 263 LEU LEU A . n 
A 1 268 SER 268 264 264 SER SER A . n 
A 1 269 GLN 269 265 265 GLN GLN A . n 
A 1 270 MET 270 266 266 MET MET A . n 
A 1 271 LEU 271 267 267 LEU LEU A . n 
A 1 272 HIS 272 268 268 HIS HIS A . n 
A 1 273 TYR 273 269 269 TYR TYR A . n 
A 1 274 ASP 274 270 270 ASP ASP A . n 
A 1 275 PRO 275 271 271 PRO PRO A . n 
A 1 276 ASN 276 272 272 ASN ASN A . n 
A 1 277 LYS 277 273 273 LYS LYS A . n 
A 1 278 ARG 278 274 274 ARG ARG A . n 
A 1 279 ILE 279 275 275 ILE ILE A . n 
A 1 280 SER 280 276 276 SER SER A . n 
A 1 281 ALA 281 277 277 ALA ALA A . n 
A 1 282 LYS 282 278 278 LYS LYS A . n 
A 1 283 ALA 283 279 279 ALA ALA A . n 
A 1 284 ALA 284 280 280 ALA ALA A . n 
A 1 285 LEU 285 281 281 LEU LEU A . n 
A 1 286 ALA 286 282 282 ALA ALA A . n 
A 1 287 HIS 287 283 283 HIS HIS A . n 
A 1 288 PRO 288 284 284 PRO PRO A . n 
A 1 289 PHE 289 285 285 PHE PHE A . n 
A 1 290 PHE 290 286 286 PHE PHE A . n 
A 1 291 GLN 291 287 287 GLN GLN A . n 
A 1 292 ASP 292 288 288 ASP ASP A . n 
A 1 293 VAL 293 289 289 VAL VAL A . n 
A 1 294 THR 294 290 290 THR THR A . n 
A 1 295 LYS 295 291 291 LYS LYS A . n 
A 1 296 PRO 296 292 292 PRO PRO A . n 
A 1 297 VAL 297 293 293 VAL VAL A . n 
A 1 298 PRO 298 294 294 PRO PRO A . n 
A 1 299 HIS 299 295 295 HIS HIS A . n 
A 1 300 LEU 300 296 296 LEU LEU A . n 
A 1 301 ARG 301 297 297 ARG ARG A . n 
A 1 302 LEU 302 298 298 LEU LEU A . n 
B 2 1   GLY 1   171 171 GLY GLY B . n 
B 2 2   VAL 2   172 172 VAL VAL B . n 
B 2 3   ASN 3   173 173 ASN ASN B . n 
B 2 4   GLU 4   174 174 GLU GLU B . n 
B 2 5   VAL 5   175 175 VAL VAL B . n 
B 2 6   PRO 6   176 176 PRO PRO B . n 
B 2 7   ASP 7   177 177 ASP ASP B . n 
B 2 8   TYR 8   178 178 TYR TYR B . n 
B 2 9   HIS 9   179 179 HIS HIS B . n 
B 2 10  GLU 10  180 180 GLU GLU B . n 
B 2 11  ASP 11  181 181 ASP ASP B . n 
B 2 12  ILE 12  182 182 ILE ILE B . n 
B 2 13  HIS 13  183 183 HIS HIS B . n 
B 2 14  THR 14  184 184 THR THR B . n 
B 2 15  TYR 15  185 185 TYR TYR B . n 
B 2 16  LEU 16  186 186 LEU LEU B . n 
B 2 17  ARG 17  187 187 ARG ARG B . n 
B 2 18  GLU 18  188 188 GLU GLU B . n 
B 2 19  MET 19  189 189 MET MET B . n 
B 2 20  GLU 20  190 190 GLU GLU B . n 
B 2 21  VAL 21  191 191 VAL VAL B . n 
B 2 22  LYS 22  192 192 LYS LYS B . n 
B 2 23  CYS 23  193 193 CYS CYS B . n 
B 2 24  LYS 24  194 194 LYS LYS B . n 
B 2 25  PRO 25  195 195 PRO PRO B . n 
B 2 26  LYS 26  196 196 LYS LYS B . n 
B 2 27  VAL 27  197 197 VAL VAL B . n 
B 2 28  GLY 28  198 198 GLY GLY B . n 
B 2 29  TYR 29  199 199 TYR TYR B . n 
B 2 30  MET 30  200 200 MET MET B . n 
B 2 31  LYS 31  201 201 LYS LYS B . n 
B 2 32  LYS 32  202 202 LYS LYS B . n 
B 2 33  GLN 33  203 203 GLN GLN B . n 
B 2 34  PRO 34  204 204 PRO PRO B . n 
B 2 35  ASP 35  205 205 ASP ASP B . n 
B 2 36  ILE 36  206 206 ILE ILE B . n 
B 2 37  THR 37  207 207 THR THR B . n 
B 2 38  ASN 38  208 208 ASN ASN B . n 
B 2 39  SER 39  209 209 SER SER B . n 
B 2 40  MET 40  210 210 MET MET B . n 
B 2 41  ARG 41  211 211 ARG ARG B . n 
B 2 42  ALA 42  212 212 ALA ALA B . n 
B 2 43  ILE 43  213 213 ILE ILE B . n 
B 2 44  LEU 44  214 214 LEU LEU B . n 
B 2 45  VAL 45  215 215 VAL VAL B . n 
B 2 46  ASP 46  216 216 ASP ASP B . n 
B 2 47  TRP 47  217 217 TRP TRP B . n 
B 2 48  LEU 48  218 218 LEU LEU B . n 
B 2 49  VAL 49  219 219 VAL VAL B . n 
B 2 50  GLU 50  220 220 GLU GLU B . n 
B 2 51  VAL 51  221 221 VAL VAL B . n 
B 2 52  GLY 52  222 222 GLY GLY B . n 
B 2 53  GLU 53  223 223 GLU GLU B . n 
B 2 54  GLU 54  224 224 GLU GLU B . n 
B 2 55  TYR 55  225 225 TYR TYR B . n 
B 2 56  LYS 56  226 226 LYS LYS B . n 
B 2 57  LEU 57  227 227 LEU LEU B . n 
B 2 58  GLN 58  228 228 GLN GLN B . n 
B 2 59  ASN 59  229 229 ASN ASN B . n 
B 2 60  GLU 60  230 230 GLU GLU B . n 
B 2 61  THR 61  231 231 THR THR B . n 
B 2 62  LEU 62  232 232 LEU LEU B . n 
B 2 63  HIS 63  233 233 HIS HIS B . n 
B 2 64  LEU 64  234 234 LEU LEU B . n 
B 2 65  ALA 65  235 235 ALA ALA B . n 
B 2 66  VAL 66  236 236 VAL VAL B . n 
B 2 67  ASN 67  237 237 ASN ASN B . n 
B 2 68  TYR 68  238 238 TYR TYR B . n 
B 2 69  ILE 69  239 239 ILE ILE B . n 
B 2 70  ASP 70  240 240 ASP ASP B . n 
B 2 71  ARG 71  241 241 ARG ARG B . n 
B 2 72  PHE 72  242 242 PHE PHE B . n 
B 2 73  LEU 73  243 243 LEU LEU B . n 
B 2 74  SER 74  244 244 SER SER B . n 
B 2 75  SER 75  245 245 SER SER B . n 
B 2 76  MET 76  246 246 MET MET B . n 
B 2 77  SER 77  247 247 SER SER B . n 
B 2 78  VAL 78  248 248 VAL VAL B . n 
B 2 79  LEU 79  249 249 LEU LEU B . n 
B 2 80  ARG 80  250 250 ARG ARG B . n 
B 2 81  GLY 81  251 251 GLY GLY B . n 
B 2 82  LYS 82  252 252 LYS LYS B . n 
B 2 83  LEU 83  253 253 LEU LEU B . n 
B 2 84  GLN 84  254 254 GLN GLN B . n 
B 2 85  LEU 85  255 255 LEU LEU B . n 
B 2 86  VAL 86  256 256 VAL VAL B . n 
B 2 87  GLY 87  257 257 GLY GLY B . n 
B 2 88  THR 88  258 258 THR THR B . n 
B 2 89  ALA 89  259 259 ALA ALA B . n 
B 2 90  ALA 90  260 260 ALA ALA B . n 
B 2 91  MET 91  261 261 MET MET B . n 
B 2 92  LEU 92  262 262 LEU LEU B . n 
B 2 93  LEU 93  263 263 LEU LEU B . n 
B 2 94  ALA 94  264 264 ALA ALA B . n 
B 2 95  SER 95  265 265 SER SER B . n 
B 2 96  LYS 96  266 266 LYS LYS B . n 
B 2 97  PHE 97  267 267 PHE PHE B . n 
B 2 98  GLU 98  268 268 GLU GLU B . n 
B 2 99  GLU 99  269 269 GLU GLU B . n 
B 2 100 ILE 100 270 270 ILE ILE B . n 
B 2 101 TYR 101 271 271 TYR TYR B . n 
B 2 102 PRO 102 272 272 PRO PRO B . n 
B 2 103 PRO 103 273 273 PRO PRO B . n 
B 2 104 GLU 104 274 274 GLU GLU B . n 
B 2 105 VAL 105 275 275 VAL VAL B . n 
B 2 106 ALA 106 276 276 ALA ALA B . n 
B 2 107 GLU 107 277 277 GLU GLU B . n 
B 2 108 PHE 108 278 278 PHE PHE B . n 
B 2 109 VAL 109 279 279 VAL VAL B . n 
B 2 110 TYR 110 280 280 TYR TYR B . n 
B 2 111 ILE 111 281 281 ILE ILE B . n 
B 2 112 THR 112 282 282 THR THR B . n 
B 2 113 ASP 113 283 283 ASP ASP B . n 
B 2 114 ASP 114 284 284 ASP ASP B . n 
B 2 115 THR 115 285 285 THR THR B . n 
B 2 116 TYR 116 286 286 TYR TYR B . n 
B 2 117 THR 117 287 287 THR THR B . n 
B 2 118 LYS 118 288 288 LYS LYS B . n 
B 2 119 LYS 119 289 289 LYS LYS B . n 
B 2 120 GLN 120 290 290 GLN GLN B . n 
B 2 121 VAL 121 291 291 VAL VAL B . n 
B 2 122 LEU 122 292 292 LEU LEU B . n 
B 2 123 ARG 123 293 293 ARG ARG B . n 
B 2 124 MET 124 294 294 MET MET B . n 
B 2 125 GLU 125 295 295 GLU GLU B . n 
B 2 126 HIS 126 296 296 HIS HIS B . n 
B 2 127 LEU 127 297 297 LEU LEU B . n 
B 2 128 VAL 128 298 298 VAL VAL B . n 
B 2 129 LEU 129 299 299 LEU LEU B . n 
B 2 130 LYS 130 300 300 LYS LYS B . n 
B 2 131 VAL 131 301 301 VAL VAL B . n 
B 2 132 LEU 132 302 302 LEU LEU B . n 
B 2 133 ALA 133 303 303 ALA ALA B . n 
B 2 134 PHE 134 304 304 PHE PHE B . n 
B 2 135 ASP 135 305 305 ASP ASP B . n 
B 2 136 LEU 136 306 306 LEU LEU B . n 
B 2 137 ALA 137 307 307 ALA ALA B . n 
B 2 138 ALA 138 308 308 ALA ALA B . n 
B 2 139 PRO 139 309 309 PRO PRO B . n 
B 2 140 THR 140 310 310 THR THR B . n 
B 2 141 ILE 141 311 311 ILE ILE B . n 
B 2 142 ASN 142 312 312 ASN ASN B . n 
B 2 143 GLN 143 313 313 GLN GLN B . n 
B 2 144 PHE 144 314 314 PHE PHE B . n 
B 2 145 LEU 145 315 315 LEU LEU B . n 
B 2 146 THR 146 316 316 THR THR B . n 
B 2 147 GLN 147 317 317 GLN GLN B . n 
B 2 148 TYR 148 318 318 TYR TYR B . n 
B 2 149 PHE 149 319 319 PHE PHE B . n 
B 2 150 LEU 150 320 320 LEU LEU B . n 
B 2 151 HIS 151 321 321 HIS HIS B . n 
B 2 152 GLN 152 322 322 GLN GLN B . n 
B 2 153 GLN 153 323 323 GLN GLN B . n 
B 2 154 PRO 154 324 324 PRO PRO B . n 
B 2 155 ALA 155 325 325 ALA ALA B . n 
B 2 156 ASN 156 326 326 ASN ASN B . n 
B 2 157 CYS 157 327 327 CYS CYS B . n 
B 2 158 LYS 158 328 328 LYS LYS B . n 
B 2 159 VAL 159 329 329 VAL VAL B . n 
B 2 160 GLU 160 330 330 GLU GLU B . n 
B 2 161 SER 161 331 331 SER SER B . n 
B 2 162 LEU 162 332 332 LEU LEU B . n 
B 2 163 ALA 163 333 333 ALA ALA B . n 
B 2 164 MET 164 334 334 MET MET B . n 
B 2 165 PHE 165 335 335 PHE PHE B . n 
B 2 166 LEU 166 336 336 LEU LEU B . n 
B 2 167 GLY 167 337 337 GLY GLY B . n 
B 2 168 GLU 168 338 338 GLU GLU B . n 
B 2 169 LEU 169 339 339 LEU LEU B . n 
B 2 170 SER 170 340 340 SER SER B . n 
B 2 171 LEU 171 341 341 LEU LEU B . n 
B 2 172 ILE 172 342 342 ILE ILE B . n 
B 2 173 ASP 173 343 343 ASP ASP B . n 
B 2 174 ALA 174 344 344 ALA ALA B . n 
B 2 175 ASP 175 345 345 ASP ASP B . n 
B 2 176 PRO 176 346 346 PRO PRO B . n 
B 2 177 TYR 177 347 347 TYR TYR B . n 
B 2 178 LEU 178 348 348 LEU LEU B . n 
B 2 179 LYS 179 349 349 LYS LYS B . n 
B 2 180 TYR 180 350 350 TYR TYR B . n 
B 2 181 LEU 181 351 351 LEU LEU B . n 
B 2 182 PRO 182 352 352 PRO PRO B . n 
B 2 183 SER 183 353 353 SER SER B . n 
B 2 184 VAL 184 354 354 VAL VAL B . n 
B 2 185 ILE 185 355 355 ILE ILE B . n 
B 2 186 ALA 186 356 356 ALA ALA B . n 
B 2 187 ALA 187 357 357 ALA ALA B . n 
B 2 188 ALA 188 358 358 ALA ALA B . n 
B 2 189 ALA 189 359 359 ALA ALA B . n 
B 2 190 PHE 190 360 360 PHE PHE B . n 
B 2 191 HIS 191 361 361 HIS HIS B . n 
B 2 192 LEU 192 362 362 LEU LEU B . n 
B 2 193 ALA 193 363 363 ALA ALA B . n 
B 2 194 LEU 194 364 364 LEU LEU B . n 
B 2 195 TYR 195 365 365 TYR TYR B . n 
B 2 196 THR 196 366 366 THR THR B . n 
B 2 197 VAL 197 367 367 VAL VAL B . n 
B 2 198 THR 198 368 368 THR THR B . n 
B 2 199 GLY 199 369 369 GLY GLY B . n 
B 2 200 GLN 200 370 370 GLN GLN B . n 
B 2 201 SER 201 371 371 SER SER B . n 
B 2 202 TRP 202 372 372 TRP TRP B . n 
B 2 203 PRO 203 373 373 PRO PRO B . n 
B 2 204 GLU 204 374 374 GLU GLU B . n 
B 2 205 SER 205 375 375 SER SER B . n 
B 2 206 LEU 206 376 376 LEU LEU B . n 
B 2 207 VAL 207 377 377 VAL VAL B . n 
B 2 208 GLN 208 378 378 GLN GLN B . n 
B 2 209 LYS 209 379 379 LYS LYS B . n 
B 2 210 THR 210 380 380 THR THR B . n 
B 2 211 GLY 211 381 381 GLY GLY B . n 
B 2 212 TYR 212 382 382 TYR TYR B . n 
B 2 213 THR 213 383 383 THR THR B . n 
B 2 214 LEU 214 384 384 LEU LEU B . n 
B 2 215 GLU 215 385 385 GLU GLU B . n 
B 2 216 THR 216 386 386 THR THR B . n 
B 2 217 LEU 217 387 387 LEU LEU B . n 
B 2 218 LYS 218 388 388 LYS LYS B . n 
B 2 219 PRO 219 389 389 PRO PRO B . n 
B 2 220 CYS 220 390 390 CYS CYS B . n 
B 2 221 LEU 221 391 391 LEU LEU B . n 
B 2 222 LEU 222 392 392 LEU LEU B . n 
B 2 223 ASP 223 393 393 ASP ASP B . n 
B 2 224 LEU 224 394 394 LEU LEU B . n 
B 2 225 HIS 225 395 395 HIS HIS B . n 
B 2 226 GLN 226 396 396 GLN GLN B . n 
B 2 227 THR 227 397 397 THR THR B . n 
B 2 228 TYR 228 398 398 TYR TYR B . n 
B 2 229 LEU 229 399 399 LEU LEU B . n 
B 2 230 ARG 230 400 400 ARG ARG B . n 
B 2 231 ALA 231 401 401 ALA ALA B . n 
B 2 232 PRO 232 402 402 PRO PRO B . n 
B 2 233 GLN 233 403 403 GLN GLN B . n 
B 2 234 HIS 234 404 404 HIS HIS B . n 
B 2 235 ALA 235 405 405 ALA ALA B . n 
B 2 236 GLN 236 406 406 GLN GLN B . n 
B 2 237 GLN 237 407 407 GLN GLN B . n 
B 2 238 SER 238 408 408 SER SER B . n 
B 2 239 ILE 239 409 409 ILE ILE B . n 
B 2 240 ARG 240 410 410 ARG ARG B . n 
B 2 241 GLU 241 411 411 GLU GLU B . n 
B 2 242 LYS 242 412 412 LYS LYS B . n 
B 2 243 TYR 243 413 413 TYR TYR B . n 
B 2 244 LYS 244 414 414 LYS LYS B . n 
B 2 245 ASN 245 415 415 ASN ASN B . n 
B 2 246 SER 246 416 416 SER SER B . n 
B 2 247 LYS 247 417 417 LYS LYS B . n 
B 2 248 TYR 248 418 418 TYR TYR B . n 
B 2 249 HIS 249 419 419 HIS HIS B . n 
B 2 250 GLY 250 420 420 GLY GLY B . n 
B 2 251 VAL 251 421 421 VAL VAL B . n 
B 2 252 SER 252 422 422 SER SER B . n 
B 2 253 LEU 253 423 423 LEU LEU B . n 
B 2 254 LEU 254 424 424 LEU LEU B . n 
B 2 255 ASN 255 425 425 ASN ASN B . n 
B 2 256 PRO 256 426 426 PRO PRO B . n 
B 2 257 PRO 257 427 427 PRO PRO B . n 
B 2 258 GLU 258 428 428 GLU GLU B . n 
B 2 259 THR 259 429 429 THR THR B . n 
B 2 260 LEU 260 430 430 LEU LEU B . n 
B 2 261 ASN 261 431 431 ASN ASN B . n 
B 2 262 VAL 262 432 ?   ?   ?   B . n 
B 2 263 HIS 263 433 ?   ?   ?   B . n 
B 2 264 HIS 264 434 ?   ?   ?   B . n 
B 2 265 HIS 265 435 ?   ?   ?   B . n 
B 2 266 HIS 266 436 ?   ?   ?   B . n 
B 2 267 HIS 267 437 ?   ?   ?   B . n 
B 2 268 HIS 268 438 ?   ?   ?   B . n 
C 1 1   GLY 1   -3  ?   ?   ?   C . n 
C 1 2   PRO 2   -2  ?   ?   ?   C . n 
C 1 3   GLY 3   -1  ?   ?   ?   C . n 
C 1 4   SER 4   0   0   SER SER C . n 
C 1 5   MET 5   1   1   MET MET C . n 
C 1 6   GLU 6   2   2   GLU GLU C . n 
C 1 7   ASN 7   3   3   ASN ASN C . n 
C 1 8   PHE 8   4   4   PHE PHE C . n 
C 1 9   GLN 9   5   5   GLN GLN C . n 
C 1 10  LYS 10  6   6   LYS LYS C . n 
C 1 11  VAL 11  7   7   VAL VAL C . n 
C 1 12  GLU 12  8   8   GLU GLU C . n 
C 1 13  LYS 13  9   9   LYS LYS C . n 
C 1 14  ILE 14  10  10  ILE ILE C . n 
C 1 15  GLY 15  11  11  GLY GLY C . n 
C 1 16  GLU 16  12  12  GLU GLU C . n 
C 1 17  GLY 17  13  13  GLY GLY C . n 
C 1 18  THR 18  14  14  THR THR C . n 
C 1 19  TYR 19  15  15  TYR TYR C . n 
C 1 20  GLY 20  16  16  GLY GLY C . n 
C 1 21  VAL 21  17  17  VAL VAL C . n 
C 1 22  VAL 22  18  18  VAL VAL C . n 
C 1 23  TYR 23  19  19  TYR TYR C . n 
C 1 24  LYS 24  20  20  LYS LYS C . n 
C 1 25  ALA 25  21  21  ALA ALA C . n 
C 1 26  ARG 26  22  22  ARG ARG C . n 
C 1 27  ASN 27  23  23  ASN ASN C . n 
C 1 28  LYS 28  24  24  LYS LYS C . n 
C 1 29  LEU 29  25  25  LEU LEU C . n 
C 1 30  THR 30  26  26  THR THR C . n 
C 1 31  GLY 31  27  27  GLY GLY C . n 
C 1 32  GLU 32  28  28  GLU GLU C . n 
C 1 33  VAL 33  29  29  VAL VAL C . n 
C 1 34  VAL 34  30  30  VAL VAL C . n 
C 1 35  ALA 35  31  31  ALA ALA C . n 
C 1 36  LEU 36  32  32  LEU LEU C . n 
C 1 37  LYS 37  33  33  LYS LYS C . n 
C 1 38  LYS 38  34  34  LYS LYS C . n 
C 1 39  ILE 39  35  35  ILE ILE C . n 
C 1 40  ARG 40  36  36  ARG ARG C . n 
C 1 41  LEU 41  37  37  LEU LEU C . n 
C 1 42  ASP 42  38  38  ASP ASP C . n 
C 1 43  THR 43  39  39  THR THR C . n 
C 1 44  GLU 44  40  40  GLU GLU C . n 
C 1 45  THR 45  41  41  THR THR C . n 
C 1 46  GLU 46  42  42  GLU GLU C . n 
C 1 47  GLY 47  43  43  GLY GLY C . n 
C 1 48  VAL 48  44  44  VAL VAL C . n 
C 1 49  PRO 49  45  45  PRO PRO C . n 
C 1 50  SER 50  46  46  SER SER C . n 
C 1 51  THR 51  47  47  THR THR C . n 
C 1 52  ALA 52  48  48  ALA ALA C . n 
C 1 53  ILE 53  49  49  ILE ILE C . n 
C 1 54  ARG 54  50  50  ARG ARG C . n 
C 1 55  GLU 55  51  51  GLU GLU C . n 
C 1 56  ILE 56  52  52  ILE ILE C . n 
C 1 57  SER 57  53  53  SER SER C . n 
C 1 58  LEU 58  54  54  LEU LEU C . n 
C 1 59  LEU 59  55  55  LEU LEU C . n 
C 1 60  LYS 60  56  56  LYS LYS C . n 
C 1 61  GLU 61  57  57  GLU GLU C . n 
C 1 62  LEU 62  58  58  LEU LEU C . n 
C 1 63  ASN 63  59  59  ASN ASN C . n 
C 1 64  HIS 64  60  60  HIS HIS C . n 
C 1 65  PRO 65  61  61  PRO PRO C . n 
C 1 66  ASN 66  62  62  ASN ASN C . n 
C 1 67  ILE 67  63  63  ILE ILE C . n 
C 1 68  VAL 68  64  64  VAL VAL C . n 
C 1 69  LYS 69  65  65  LYS LYS C . n 
C 1 70  LEU 70  66  66  LEU LEU C . n 
C 1 71  LEU 71  67  67  LEU LEU C . n 
C 1 72  ASP 72  68  68  ASP ASP C . n 
C 1 73  VAL 73  69  69  VAL VAL C . n 
C 1 74  ILE 74  70  70  ILE ILE C . n 
C 1 75  HIS 75  71  71  HIS HIS C . n 
C 1 76  THR 76  72  72  THR THR C . n 
C 1 77  GLU 77  73  73  GLU GLU C . n 
C 1 78  ASN 78  74  74  ASN ASN C . n 
C 1 79  LYS 79  75  75  LYS LYS C . n 
C 1 80  LEU 80  76  76  LEU LEU C . n 
C 1 81  TYR 81  77  77  TYR TYR C . n 
C 1 82  LEU 82  78  78  LEU LEU C . n 
C 1 83  VAL 83  79  79  VAL VAL C . n 
C 1 84  PHE 84  80  80  PHE PHE C . n 
C 1 85  GLU 85  81  81  GLU GLU C . n 
C 1 86  PHE 86  82  82  PHE PHE C . n 
C 1 87  LEU 87  83  83  LEU LEU C . n 
C 1 88  HIS 88  84  84  HIS HIS C . n 
C 1 89  GLN 89  85  85  GLN GLN C . n 
C 1 90  ASP 90  86  86  ASP ASP C . n 
C 1 91  LEU 91  87  87  LEU LEU C . n 
C 1 92  LYS 92  88  88  LYS LYS C . n 
C 1 93  LYS 93  89  89  LYS LYS C . n 
C 1 94  PHE 94  90  90  PHE PHE C . n 
C 1 95  MET 95  91  91  MET MET C . n 
C 1 96  ASP 96  92  92  ASP ASP C . n 
C 1 97  ALA 97  93  93  ALA ALA C . n 
C 1 98  SER 98  94  94  SER SER C . n 
C 1 99  ALA 99  95  95  ALA ALA C . n 
C 1 100 LEU 100 96  96  LEU LEU C . n 
C 1 101 THR 101 97  97  THR THR C . n 
C 1 102 GLY 102 98  98  GLY GLY C . n 
C 1 103 ILE 103 99  99  ILE ILE C . n 
C 1 104 PRO 104 100 100 PRO PRO C . n 
C 1 105 LEU 105 101 101 LEU LEU C . n 
C 1 106 PRO 106 102 102 PRO PRO C . n 
C 1 107 LEU 107 103 103 LEU LEU C . n 
C 1 108 ILE 108 104 104 ILE ILE C . n 
C 1 109 LYS 109 105 105 LYS LYS C . n 
C 1 110 SER 110 106 106 SER SER C . n 
C 1 111 TYR 111 107 107 TYR TYR C . n 
C 1 112 LEU 112 108 108 LEU LEU C . n 
C 1 113 PHE 113 109 109 PHE PHE C . n 
C 1 114 GLN 114 110 110 GLN GLN C . n 
C 1 115 LEU 115 111 111 LEU LEU C . n 
C 1 116 LEU 116 112 112 LEU LEU C . n 
C 1 117 GLN 117 113 113 GLN GLN C . n 
C 1 118 GLY 118 114 114 GLY GLY C . n 
C 1 119 LEU 119 115 115 LEU LEU C . n 
C 1 120 ALA 120 116 116 ALA ALA C . n 
C 1 121 PHE 121 117 117 PHE PHE C . n 
C 1 122 CYS 122 118 118 CYS CYS C . n 
C 1 123 HIS 123 119 119 HIS HIS C . n 
C 1 124 SER 124 120 120 SER SER C . n 
C 1 125 HIS 125 121 121 HIS HIS C . n 
C 1 126 ARG 126 122 122 ARG ARG C . n 
C 1 127 VAL 127 123 123 VAL VAL C . n 
C 1 128 LEU 128 124 124 LEU LEU C . n 
C 1 129 HIS 129 125 125 HIS HIS C . n 
C 1 130 ARG 130 126 126 ARG ARG C . n 
C 1 131 ASP 131 127 127 ASP ASP C . n 
C 1 132 LEU 132 128 128 LEU LEU C . n 
C 1 133 LYS 133 129 129 LYS LYS C . n 
C 1 134 PRO 134 130 130 PRO PRO C . n 
C 1 135 GLN 135 131 131 GLN GLN C . n 
C 1 136 ASN 136 132 132 ASN ASN C . n 
C 1 137 LEU 137 133 133 LEU LEU C . n 
C 1 138 LEU 138 134 134 LEU LEU C . n 
C 1 139 ILE 139 135 135 ILE ILE C . n 
C 1 140 ASN 140 136 136 ASN ASN C . n 
C 1 141 THR 141 137 137 THR THR C . n 
C 1 142 GLU 142 138 138 GLU GLU C . n 
C 1 143 GLY 143 139 139 GLY GLY C . n 
C 1 144 ALA 144 140 140 ALA ALA C . n 
C 1 145 ILE 145 141 141 ILE ILE C . n 
C 1 146 LYS 146 142 142 LYS LYS C . n 
C 1 147 LEU 147 143 143 LEU LEU C . n 
C 1 148 ALA 148 144 144 ALA ALA C . n 
C 1 149 ASP 149 145 145 ASP ASP C . n 
C 1 150 PHE 150 146 146 PHE PHE C . n 
C 1 151 GLY 151 147 147 GLY GLY C . n 
C 1 152 LEU 152 148 148 LEU LEU C . n 
C 1 153 ALA 153 149 149 ALA ALA C . n 
C 1 154 ARG 154 150 150 ARG ARG C . n 
C 1 155 ALA 155 151 151 ALA ALA C . n 
C 1 156 PHE 156 152 152 PHE PHE C . n 
C 1 157 GLY 157 153 153 GLY GLY C . n 
C 1 158 VAL 158 154 154 VAL VAL C . n 
C 1 159 PRO 159 155 155 PRO PRO C . n 
C 1 160 VAL 160 156 156 VAL VAL C . n 
C 1 161 ARG 161 157 157 ARG ARG C . n 
C 1 162 THR 162 158 158 THR THR C . n 
C 1 163 TYR 163 159 159 TYR TYR C . n 
C 1 164 TPO 164 160 160 TPO TPO C . n 
C 1 165 HIS 165 161 161 HIS HIS C . n 
C 1 166 GLU 166 162 162 GLU GLU C . n 
C 1 167 VAL 167 163 163 VAL VAL C . n 
C 1 168 VAL 168 164 164 VAL VAL C . n 
C 1 169 THR 169 165 165 THR THR C . n 
C 1 170 LEU 170 166 166 LEU LEU C . n 
C 1 171 TRP 171 167 167 TRP TRP C . n 
C 1 172 TYR 172 168 168 TYR TYR C . n 
C 1 173 ARG 173 169 169 ARG ARG C . n 
C 1 174 ALA 174 170 170 ALA ALA C . n 
C 1 175 PRO 175 171 171 PRO PRO C . n 
C 1 176 GLU 176 172 172 GLU GLU C . n 
C 1 177 ILE 177 173 173 ILE ILE C . n 
C 1 178 LEU 178 174 174 LEU LEU C . n 
C 1 179 LEU 179 175 175 LEU LEU C . n 
C 1 180 GLY 180 176 176 GLY GLY C . n 
C 1 181 CYS 181 177 177 CYS CYS C . n 
C 1 182 LYS 182 178 178 LYS LYS C . n 
C 1 183 TYR 183 179 179 TYR TYR C . n 
C 1 184 TYR 184 180 180 TYR TYR C . n 
C 1 185 SER 185 181 181 SER SER C . n 
C 1 186 THR 186 182 182 THR THR C . n 
C 1 187 ALA 187 183 183 ALA ALA C . n 
C 1 188 VAL 188 184 184 VAL VAL C . n 
C 1 189 ASP 189 185 185 ASP ASP C . n 
C 1 190 ILE 190 186 186 ILE ILE C . n 
C 1 191 TRP 191 187 187 TRP TRP C . n 
C 1 192 SER 192 188 188 SER SER C . n 
C 1 193 LEU 193 189 189 LEU LEU C . n 
C 1 194 GLY 194 190 190 GLY GLY C . n 
C 1 195 CYS 195 191 191 CYS CYS C . n 
C 1 196 ILE 196 192 192 ILE ILE C . n 
C 1 197 PHE 197 193 193 PHE PHE C . n 
C 1 198 ALA 198 194 194 ALA ALA C . n 
C 1 199 GLU 199 195 195 GLU GLU C . n 
C 1 200 MET 200 196 196 MET MET C . n 
C 1 201 VAL 201 197 197 VAL VAL C . n 
C 1 202 THR 202 198 198 THR THR C . n 
C 1 203 ARG 203 199 199 ARG ARG C . n 
C 1 204 ARG 204 200 200 ARG ARG C . n 
C 1 205 ALA 205 201 201 ALA ALA C . n 
C 1 206 LEU 206 202 202 LEU LEU C . n 
C 1 207 PHE 207 203 203 PHE PHE C . n 
C 1 208 PRO 208 204 204 PRO PRO C . n 
C 1 209 GLY 209 205 205 GLY GLY C . n 
C 1 210 ASP 210 206 206 ASP ASP C . n 
C 1 211 SER 211 207 207 SER SER C . n 
C 1 212 GLU 212 208 208 GLU GLU C . n 
C 1 213 ILE 213 209 209 ILE ILE C . n 
C 1 214 ASP 214 210 210 ASP ASP C . n 
C 1 215 GLN 215 211 211 GLN GLN C . n 
C 1 216 LEU 216 212 212 LEU LEU C . n 
C 1 217 PHE 217 213 213 PHE PHE C . n 
C 1 218 ARG 218 214 214 ARG ARG C . n 
C 1 219 ILE 219 215 215 ILE ILE C . n 
C 1 220 PHE 220 216 216 PHE PHE C . n 
C 1 221 ARG 221 217 217 ARG ARG C . n 
C 1 222 THR 222 218 218 THR THR C . n 
C 1 223 LEU 223 219 219 LEU LEU C . n 
C 1 224 GLY 224 220 220 GLY GLY C . n 
C 1 225 THR 225 221 221 THR THR C . n 
C 1 226 PRO 226 222 222 PRO PRO C . n 
C 1 227 ASP 227 223 223 ASP ASP C . n 
C 1 228 GLU 228 224 224 GLU GLU C . n 
C 1 229 VAL 229 225 225 VAL VAL C . n 
C 1 230 VAL 230 226 226 VAL VAL C . n 
C 1 231 TRP 231 227 227 TRP TRP C . n 
C 1 232 PRO 232 228 228 PRO PRO C . n 
C 1 233 GLY 233 229 229 GLY GLY C . n 
C 1 234 VAL 234 230 230 VAL VAL C . n 
C 1 235 THR 235 231 231 THR THR C . n 
C 1 236 SER 236 232 232 SER SER C . n 
C 1 237 MET 237 233 233 MET MET C . n 
C 1 238 PRO 238 234 234 PRO PRO C . n 
C 1 239 ASP 239 235 235 ASP ASP C . n 
C 1 240 TYR 240 236 236 TYR TYR C . n 
C 1 241 LYS 241 237 237 LYS LYS C . n 
C 1 242 PRO 242 238 238 PRO PRO C . n 
C 1 243 SER 243 239 239 SER SER C . n 
C 1 244 PHE 244 240 240 PHE PHE C . n 
C 1 245 PRO 245 241 241 PRO PRO C . n 
C 1 246 LYS 246 242 242 LYS LYS C . n 
C 1 247 TRP 247 243 243 TRP TRP C . n 
C 1 248 ALA 248 244 244 ALA ALA C . n 
C 1 249 ARG 249 245 245 ARG ARG C . n 
C 1 250 GLN 250 246 246 GLN GLN C . n 
C 1 251 ASP 251 247 247 ASP ASP C . n 
C 1 252 PHE 252 248 248 PHE PHE C . n 
C 1 253 SER 253 249 249 SER SER C . n 
C 1 254 LYS 254 250 250 LYS LYS C . n 
C 1 255 VAL 255 251 251 VAL VAL C . n 
C 1 256 VAL 256 252 252 VAL VAL C . n 
C 1 257 PRO 257 253 253 PRO PRO C . n 
C 1 258 PRO 258 254 254 PRO PRO C . n 
C 1 259 LEU 259 255 255 LEU LEU C . n 
C 1 260 ASP 260 256 256 ASP ASP C . n 
C 1 261 GLU 261 257 257 GLU GLU C . n 
C 1 262 ASP 262 258 258 ASP ASP C . n 
C 1 263 GLY 263 259 259 GLY GLY C . n 
C 1 264 ARG 264 260 260 ARG ARG C . n 
C 1 265 SER 265 261 261 SER SER C . n 
C 1 266 LEU 266 262 262 LEU LEU C . n 
C 1 267 LEU 267 263 263 LEU LEU C . n 
C 1 268 SER 268 264 264 SER SER C . n 
C 1 269 GLN 269 265 265 GLN GLN C . n 
C 1 270 MET 270 266 266 MET MET C . n 
C 1 271 LEU 271 267 267 LEU LEU C . n 
C 1 272 HIS 272 268 268 HIS HIS C . n 
C 1 273 TYR 273 269 269 TYR TYR C . n 
C 1 274 ASP 274 270 270 ASP ASP C . n 
C 1 275 PRO 275 271 271 PRO PRO C . n 
C 1 276 ASN 276 272 272 ASN ASN C . n 
C 1 277 LYS 277 273 273 LYS LYS C . n 
C 1 278 ARG 278 274 274 ARG ARG C . n 
C 1 279 ILE 279 275 275 ILE ILE C . n 
C 1 280 SER 280 276 276 SER SER C . n 
C 1 281 ALA 281 277 277 ALA ALA C . n 
C 1 282 LYS 282 278 278 LYS LYS C . n 
C 1 283 ALA 283 279 279 ALA ALA C . n 
C 1 284 ALA 284 280 280 ALA ALA C . n 
C 1 285 LEU 285 281 281 LEU LEU C . n 
C 1 286 ALA 286 282 282 ALA ALA C . n 
C 1 287 HIS 287 283 283 HIS HIS C . n 
C 1 288 PRO 288 284 284 PRO PRO C . n 
C 1 289 PHE 289 285 285 PHE PHE C . n 
C 1 290 PHE 290 286 286 PHE PHE C . n 
C 1 291 GLN 291 287 287 GLN GLN C . n 
C 1 292 ASP 292 288 288 ASP ASP C . n 
C 1 293 VAL 293 289 289 VAL VAL C . n 
C 1 294 THR 294 290 290 THR THR C . n 
C 1 295 LYS 295 291 291 LYS LYS C . n 
C 1 296 PRO 296 292 292 PRO PRO C . n 
C 1 297 VAL 297 293 293 VAL VAL C . n 
C 1 298 PRO 298 294 294 PRO PRO C . n 
C 1 299 HIS 299 295 295 HIS HIS C . n 
C 1 300 LEU 300 296 296 LEU LEU C . n 
C 1 301 ARG 301 297 ?   ?   ?   C . n 
C 1 302 LEU 302 298 ?   ?   ?   C . n 
D 2 1   GLY 1   171 171 GLY GLY D . n 
D 2 2   VAL 2   172 172 VAL VAL D . n 
D 2 3   ASN 3   173 173 ASN ASN D . n 
D 2 4   GLU 4   174 174 GLU GLU D . n 
D 2 5   VAL 5   175 175 VAL VAL D . n 
D 2 6   PRO 6   176 176 PRO PRO D . n 
D 2 7   ASP 7   177 177 ASP ASP D . n 
D 2 8   TYR 8   178 178 TYR TYR D . n 
D 2 9   HIS 9   179 179 HIS HIS D . n 
D 2 10  GLU 10  180 180 GLU GLU D . n 
D 2 11  ASP 11  181 181 ASP ASP D . n 
D 2 12  ILE 12  182 182 ILE ILE D . n 
D 2 13  HIS 13  183 183 HIS HIS D . n 
D 2 14  THR 14  184 184 THR THR D . n 
D 2 15  TYR 15  185 185 TYR TYR D . n 
D 2 16  LEU 16  186 186 LEU LEU D . n 
D 2 17  ARG 17  187 187 ARG ARG D . n 
D 2 18  GLU 18  188 188 GLU GLU D . n 
D 2 19  MET 19  189 189 MET MET D . n 
D 2 20  GLU 20  190 190 GLU GLU D . n 
D 2 21  VAL 21  191 191 VAL VAL D . n 
D 2 22  LYS 22  192 192 LYS LYS D . n 
D 2 23  CYS 23  193 193 CYS CYS D . n 
D 2 24  LYS 24  194 194 LYS LYS D . n 
D 2 25  PRO 25  195 195 PRO PRO D . n 
D 2 26  LYS 26  196 196 LYS LYS D . n 
D 2 27  VAL 27  197 197 VAL VAL D . n 
D 2 28  GLY 28  198 198 GLY GLY D . n 
D 2 29  TYR 29  199 199 TYR TYR D . n 
D 2 30  MET 30  200 200 MET MET D . n 
D 2 31  LYS 31  201 201 LYS LYS D . n 
D 2 32  LYS 32  202 202 LYS LYS D . n 
D 2 33  GLN 33  203 203 GLN GLN D . n 
D 2 34  PRO 34  204 204 PRO PRO D . n 
D 2 35  ASP 35  205 205 ASP ASP D . n 
D 2 36  ILE 36  206 206 ILE ILE D . n 
D 2 37  THR 37  207 207 THR THR D . n 
D 2 38  ASN 38  208 208 ASN ASN D . n 
D 2 39  SER 39  209 209 SER SER D . n 
D 2 40  MET 40  210 210 MET MET D . n 
D 2 41  ARG 41  211 211 ARG ARG D . n 
D 2 42  ALA 42  212 212 ALA ALA D . n 
D 2 43  ILE 43  213 213 ILE ILE D . n 
D 2 44  LEU 44  214 214 LEU LEU D . n 
D 2 45  VAL 45  215 215 VAL VAL D . n 
D 2 46  ASP 46  216 216 ASP ASP D . n 
D 2 47  TRP 47  217 217 TRP TRP D . n 
D 2 48  LEU 48  218 218 LEU LEU D . n 
D 2 49  VAL 49  219 219 VAL VAL D . n 
D 2 50  GLU 50  220 220 GLU GLU D . n 
D 2 51  VAL 51  221 221 VAL VAL D . n 
D 2 52  GLY 52  222 222 GLY GLY D . n 
D 2 53  GLU 53  223 223 GLU GLU D . n 
D 2 54  GLU 54  224 224 GLU GLU D . n 
D 2 55  TYR 55  225 225 TYR TYR D . n 
D 2 56  LYS 56  226 226 LYS LYS D . n 
D 2 57  LEU 57  227 227 LEU LEU D . n 
D 2 58  GLN 58  228 228 GLN GLN D . n 
D 2 59  ASN 59  229 229 ASN ASN D . n 
D 2 60  GLU 60  230 230 GLU GLU D . n 
D 2 61  THR 61  231 231 THR THR D . n 
D 2 62  LEU 62  232 232 LEU LEU D . n 
D 2 63  HIS 63  233 233 HIS HIS D . n 
D 2 64  LEU 64  234 234 LEU LEU D . n 
D 2 65  ALA 65  235 235 ALA ALA D . n 
D 2 66  VAL 66  236 236 VAL VAL D . n 
D 2 67  ASN 67  237 237 ASN ASN D . n 
D 2 68  TYR 68  238 238 TYR TYR D . n 
D 2 69  ILE 69  239 239 ILE ILE D . n 
D 2 70  ASP 70  240 240 ASP ASP D . n 
D 2 71  ARG 71  241 241 ARG ARG D . n 
D 2 72  PHE 72  242 242 PHE PHE D . n 
D 2 73  LEU 73  243 243 LEU LEU D . n 
D 2 74  SER 74  244 244 SER SER D . n 
D 2 75  SER 75  245 245 SER SER D . n 
D 2 76  MET 76  246 246 MET MET D . n 
D 2 77  SER 77  247 247 SER SER D . n 
D 2 78  VAL 78  248 248 VAL VAL D . n 
D 2 79  LEU 79  249 249 LEU LEU D . n 
D 2 80  ARG 80  250 250 ARG ARG D . n 
D 2 81  GLY 81  251 251 GLY GLY D . n 
D 2 82  LYS 82  252 252 LYS LYS D . n 
D 2 83  LEU 83  253 253 LEU LEU D . n 
D 2 84  GLN 84  254 254 GLN GLN D . n 
D 2 85  LEU 85  255 255 LEU LEU D . n 
D 2 86  VAL 86  256 256 VAL VAL D . n 
D 2 87  GLY 87  257 257 GLY GLY D . n 
D 2 88  THR 88  258 258 THR THR D . n 
D 2 89  ALA 89  259 259 ALA ALA D . n 
D 2 90  ALA 90  260 260 ALA ALA D . n 
D 2 91  MET 91  261 261 MET MET D . n 
D 2 92  LEU 92  262 262 LEU LEU D . n 
D 2 93  LEU 93  263 263 LEU LEU D . n 
D 2 94  ALA 94  264 264 ALA ALA D . n 
D 2 95  SER 95  265 265 SER SER D . n 
D 2 96  LYS 96  266 266 LYS LYS D . n 
D 2 97  PHE 97  267 267 PHE PHE D . n 
D 2 98  GLU 98  268 268 GLU GLU D . n 
D 2 99  GLU 99  269 269 GLU GLU D . n 
D 2 100 ILE 100 270 270 ILE ILE D . n 
D 2 101 TYR 101 271 271 TYR TYR D . n 
D 2 102 PRO 102 272 272 PRO PRO D . n 
D 2 103 PRO 103 273 273 PRO PRO D . n 
D 2 104 GLU 104 274 274 GLU GLU D . n 
D 2 105 VAL 105 275 275 VAL VAL D . n 
D 2 106 ALA 106 276 276 ALA ALA D . n 
D 2 107 GLU 107 277 277 GLU GLU D . n 
D 2 108 PHE 108 278 278 PHE PHE D . n 
D 2 109 VAL 109 279 279 VAL VAL D . n 
D 2 110 TYR 110 280 280 TYR TYR D . n 
D 2 111 ILE 111 281 281 ILE ILE D . n 
D 2 112 THR 112 282 282 THR THR D . n 
D 2 113 ASP 113 283 283 ASP ASP D . n 
D 2 114 ASP 114 284 284 ASP ASP D . n 
D 2 115 THR 115 285 285 THR THR D . n 
D 2 116 TYR 116 286 286 TYR TYR D . n 
D 2 117 THR 117 287 287 THR THR D . n 
D 2 118 LYS 118 288 288 LYS LYS D . n 
D 2 119 LYS 119 289 289 LYS LYS D . n 
D 2 120 GLN 120 290 290 GLN GLN D . n 
D 2 121 VAL 121 291 291 VAL VAL D . n 
D 2 122 LEU 122 292 292 LEU LEU D . n 
D 2 123 ARG 123 293 293 ARG ARG D . n 
D 2 124 MET 124 294 294 MET MET D . n 
D 2 125 GLU 125 295 295 GLU GLU D . n 
D 2 126 HIS 126 296 296 HIS HIS D . n 
D 2 127 LEU 127 297 297 LEU LEU D . n 
D 2 128 VAL 128 298 298 VAL VAL D . n 
D 2 129 LEU 129 299 299 LEU LEU D . n 
D 2 130 LYS 130 300 300 LYS LYS D . n 
D 2 131 VAL 131 301 301 VAL VAL D . n 
D 2 132 LEU 132 302 302 LEU LEU D . n 
D 2 133 ALA 133 303 303 ALA ALA D . n 
D 2 134 PHE 134 304 304 PHE PHE D . n 
D 2 135 ASP 135 305 305 ASP ASP D . n 
D 2 136 LEU 136 306 306 LEU LEU D . n 
D 2 137 ALA 137 307 307 ALA ALA D . n 
D 2 138 ALA 138 308 308 ALA ALA D . n 
D 2 139 PRO 139 309 309 PRO PRO D . n 
D 2 140 THR 140 310 310 THR THR D . n 
D 2 141 ILE 141 311 311 ILE ILE D . n 
D 2 142 ASN 142 312 312 ASN ASN D . n 
D 2 143 GLN 143 313 313 GLN GLN D . n 
D 2 144 PHE 144 314 314 PHE PHE D . n 
D 2 145 LEU 145 315 315 LEU LEU D . n 
D 2 146 THR 146 316 316 THR THR D . n 
D 2 147 GLN 147 317 317 GLN GLN D . n 
D 2 148 TYR 148 318 318 TYR TYR D . n 
D 2 149 PHE 149 319 319 PHE PHE D . n 
D 2 150 LEU 150 320 320 LEU LEU D . n 
D 2 151 HIS 151 321 321 HIS HIS D . n 
D 2 152 GLN 152 322 322 GLN GLN D . n 
D 2 153 GLN 153 323 323 GLN GLN D . n 
D 2 154 PRO 154 324 324 PRO PRO D . n 
D 2 155 ALA 155 325 325 ALA ALA D . n 
D 2 156 ASN 156 326 326 ASN ASN D . n 
D 2 157 CYS 157 327 327 CYS CYS D . n 
D 2 158 LYS 158 328 328 LYS LYS D . n 
D 2 159 VAL 159 329 329 VAL VAL D . n 
D 2 160 GLU 160 330 330 GLU GLU D . n 
D 2 161 SER 161 331 331 SER SER D . n 
D 2 162 LEU 162 332 332 LEU LEU D . n 
D 2 163 ALA 163 333 333 ALA ALA D . n 
D 2 164 MET 164 334 334 MET MET D . n 
D 2 165 PHE 165 335 335 PHE PHE D . n 
D 2 166 LEU 166 336 336 LEU LEU D . n 
D 2 167 GLY 167 337 337 GLY GLY D . n 
D 2 168 GLU 168 338 338 GLU GLU D . n 
D 2 169 LEU 169 339 339 LEU LEU D . n 
D 2 170 SER 170 340 340 SER SER D . n 
D 2 171 LEU 171 341 341 LEU LEU D . n 
D 2 172 ILE 172 342 342 ILE ILE D . n 
D 2 173 ASP 173 343 343 ASP ASP D . n 
D 2 174 ALA 174 344 344 ALA ALA D . n 
D 2 175 ASP 175 345 345 ASP ASP D . n 
D 2 176 PRO 176 346 346 PRO PRO D . n 
D 2 177 TYR 177 347 347 TYR TYR D . n 
D 2 178 LEU 178 348 348 LEU LEU D . n 
D 2 179 LYS 179 349 349 LYS LYS D . n 
D 2 180 TYR 180 350 350 TYR TYR D . n 
D 2 181 LEU 181 351 351 LEU LEU D . n 
D 2 182 PRO 182 352 352 PRO PRO D . n 
D 2 183 SER 183 353 353 SER SER D . n 
D 2 184 VAL 184 354 354 VAL VAL D . n 
D 2 185 ILE 185 355 355 ILE ILE D . n 
D 2 186 ALA 186 356 356 ALA ALA D . n 
D 2 187 ALA 187 357 357 ALA ALA D . n 
D 2 188 ALA 188 358 358 ALA ALA D . n 
D 2 189 ALA 189 359 359 ALA ALA D . n 
D 2 190 PHE 190 360 360 PHE PHE D . n 
D 2 191 HIS 191 361 361 HIS HIS D . n 
D 2 192 LEU 192 362 362 LEU LEU D . n 
D 2 193 ALA 193 363 363 ALA ALA D . n 
D 2 194 LEU 194 364 364 LEU LEU D . n 
D 2 195 TYR 195 365 365 TYR TYR D . n 
D 2 196 THR 196 366 366 THR THR D . n 
D 2 197 VAL 197 367 367 VAL VAL D . n 
D 2 198 THR 198 368 368 THR THR D . n 
D 2 199 GLY 199 369 369 GLY GLY D . n 
D 2 200 GLN 200 370 370 GLN GLN D . n 
D 2 201 SER 201 371 371 SER SER D . n 
D 2 202 TRP 202 372 372 TRP TRP D . n 
D 2 203 PRO 203 373 373 PRO PRO D . n 
D 2 204 GLU 204 374 374 GLU GLU D . n 
D 2 205 SER 205 375 375 SER SER D . n 
D 2 206 LEU 206 376 376 LEU LEU D . n 
D 2 207 VAL 207 377 377 VAL VAL D . n 
D 2 208 GLN 208 378 378 GLN GLN D . n 
D 2 209 LYS 209 379 379 LYS LYS D . n 
D 2 210 THR 210 380 380 THR THR D . n 
D 2 211 GLY 211 381 381 GLY GLY D . n 
D 2 212 TYR 212 382 382 TYR TYR D . n 
D 2 213 THR 213 383 383 THR THR D . n 
D 2 214 LEU 214 384 384 LEU LEU D . n 
D 2 215 GLU 215 385 385 GLU GLU D . n 
D 2 216 THR 216 386 386 THR THR D . n 
D 2 217 LEU 217 387 387 LEU LEU D . n 
D 2 218 LYS 218 388 388 LYS LYS D . n 
D 2 219 PRO 219 389 389 PRO PRO D . n 
D 2 220 CYS 220 390 390 CYS CYS D . n 
D 2 221 LEU 221 391 391 LEU LEU D . n 
D 2 222 LEU 222 392 392 LEU LEU D . n 
D 2 223 ASP 223 393 393 ASP ASP D . n 
D 2 224 LEU 224 394 394 LEU LEU D . n 
D 2 225 HIS 225 395 395 HIS HIS D . n 
D 2 226 GLN 226 396 396 GLN GLN D . n 
D 2 227 THR 227 397 397 THR THR D . n 
D 2 228 TYR 228 398 398 TYR TYR D . n 
D 2 229 LEU 229 399 399 LEU LEU D . n 
D 2 230 ARG 230 400 400 ARG ARG D . n 
D 2 231 ALA 231 401 401 ALA ALA D . n 
D 2 232 PRO 232 402 402 PRO PRO D . n 
D 2 233 GLN 233 403 403 GLN GLN D . n 
D 2 234 HIS 234 404 404 HIS HIS D . n 
D 2 235 ALA 235 405 405 ALA ALA D . n 
D 2 236 GLN 236 406 406 GLN GLN D . n 
D 2 237 GLN 237 407 407 GLN GLN D . n 
D 2 238 SER 238 408 408 SER SER D . n 
D 2 239 ILE 239 409 409 ILE ILE D . n 
D 2 240 ARG 240 410 410 ARG ARG D . n 
D 2 241 GLU 241 411 411 GLU GLU D . n 
D 2 242 LYS 242 412 412 LYS LYS D . n 
D 2 243 TYR 243 413 413 TYR TYR D . n 
D 2 244 LYS 244 414 414 LYS LYS D . n 
D 2 245 ASN 245 415 415 ASN ASN D . n 
D 2 246 SER 246 416 416 SER SER D . n 
D 2 247 LYS 247 417 417 LYS LYS D . n 
D 2 248 TYR 248 418 418 TYR TYR D . n 
D 2 249 HIS 249 419 419 HIS HIS D . n 
D 2 250 GLY 250 420 420 GLY GLY D . n 
D 2 251 VAL 251 421 421 VAL VAL D . n 
D 2 252 SER 252 422 422 SER SER D . n 
D 2 253 LEU 253 423 423 LEU LEU D . n 
D 2 254 LEU 254 424 424 LEU LEU D . n 
D 2 255 ASN 255 425 425 ASN ASN D . n 
D 2 256 PRO 256 426 426 PRO PRO D . n 
D 2 257 PRO 257 427 427 PRO PRO D . n 
D 2 258 GLU 258 428 428 GLU GLU D . n 
D 2 259 THR 259 429 429 THR THR D . n 
D 2 260 LEU 260 430 430 LEU LEU D . n 
D 2 261 ASN 261 431 431 ASN ASN D . n 
D 2 262 VAL 262 432 432 VAL VAL D . n 
D 2 263 HIS 263 433 ?   ?   ?   D . n 
D 2 264 HIS 264 434 ?   ?   ?   D . n 
D 2 265 HIS 265 435 ?   ?   ?   D . n 
D 2 266 HIS 266 436 ?   ?   ?   D . n 
D 2 267 HIS 267 437 ?   ?   ?   D . n 
D 2 268 HIS 268 438 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        IJX 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   IJX 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 IJX 1   301 502 IJX DRG A . 
F 3 IJX 1   302 503 IJX DRG A . 
G 3 IJX 1   501 501 IJX DRG B . 
H 3 IJX 1   501 501 IJX DRG C . 
I 4 HOH 1   401 468 HOH HOH A . 
I 4 HOH 2   402 566 HOH HOH A . 
I 4 HOH 3   403 441 HOH HOH A . 
I 4 HOH 4   404 401 HOH HOH A . 
I 4 HOH 5   405 421 HOH HOH A . 
I 4 HOH 6   406 404 HOH HOH A . 
I 4 HOH 7   407 515 HOH HOH A . 
I 4 HOH 8   408 486 HOH HOH A . 
I 4 HOH 9   409 407 HOH HOH A . 
I 4 HOH 10  410 479 HOH HOH A . 
I 4 HOH 11  411 440 HOH HOH A . 
I 4 HOH 12  412 39  HOH HOH A . 
I 4 HOH 13  413 85  HOH HOH A . 
I 4 HOH 14  414 475 HOH HOH A . 
I 4 HOH 15  415 425 HOH HOH A . 
I 4 HOH 16  416 436 HOH HOH A . 
I 4 HOH 17  417 79  HOH HOH A . 
I 4 HOH 18  418 465 HOH HOH A . 
I 4 HOH 19  419 72  HOH HOH A . 
I 4 HOH 20  420 525 HOH HOH A . 
I 4 HOH 21  421 525 HOH HOH A . 
I 4 HOH 22  422 459 HOH HOH A . 
I 4 HOH 23  423 432 HOH HOH A . 
I 4 HOH 24  424 467 HOH HOH A . 
I 4 HOH 25  425 59  HOH HOH A . 
I 4 HOH 26  426 38  HOH HOH A . 
I 4 HOH 27  427 504 HOH HOH A . 
I 4 HOH 28  428 474 HOH HOH A . 
I 4 HOH 29  429 520 HOH HOH A . 
I 4 HOH 30  430 523 HOH HOH A . 
I 4 HOH 31  431 472 HOH HOH A . 
I 4 HOH 32  432 454 HOH HOH A . 
I 4 HOH 33  433 456 HOH HOH A . 
I 4 HOH 34  434 490 HOH HOH A . 
I 4 HOH 35  435 30  HOH HOH A . 
I 4 HOH 36  436 428 HOH HOH A . 
I 4 HOH 37  437 64  HOH HOH A . 
I 4 HOH 38  438 444 HOH HOH A . 
I 4 HOH 39  439 478 HOH HOH A . 
I 4 HOH 40  440 469 HOH HOH A . 
I 4 HOH 41  441 430 HOH HOH A . 
I 4 HOH 42  442 480 HOH HOH A . 
I 4 HOH 43  443 461 HOH HOH A . 
I 4 HOH 44  444 427 HOH HOH A . 
I 4 HOH 45  445 447 HOH HOH A . 
I 4 HOH 46  446 416 HOH HOH A . 
I 4 HOH 47  447 424 HOH HOH A . 
I 4 HOH 48  448 491 HOH HOH A . 
I 4 HOH 49  449 462 HOH HOH A . 
I 4 HOH 50  450 470 HOH HOH A . 
I 4 HOH 51  451 77  HOH HOH A . 
I 4 HOH 52  452 448 HOH HOH A . 
I 4 HOH 53  453 563 HOH HOH A . 
I 4 HOH 54  454 503 HOH HOH A . 
I 4 HOH 55  455 11  HOH HOH A . 
I 4 HOH 56  456 464 HOH HOH A . 
I 4 HOH 57  457 487 HOH HOH A . 
I 4 HOH 58  458 477 HOH HOH A . 
I 4 HOH 59  459 509 HOH HOH A . 
I 4 HOH 60  460 496 HOH HOH A . 
I 4 HOH 61  461 510 HOH HOH A . 
I 4 HOH 62  462 420 HOH HOH A . 
I 4 HOH 63  463 451 HOH HOH A . 
I 4 HOH 64  464 457 HOH HOH A . 
I 4 HOH 65  465 438 HOH HOH A . 
I 4 HOH 66  466 521 HOH HOH A . 
I 4 HOH 67  467 31  HOH HOH A . 
I 4 HOH 68  468 517 HOH HOH A . 
I 4 HOH 69  469 573 HOH HOH A . 
I 4 HOH 70  470 435 HOH HOH A . 
I 4 HOH 71  471 35  HOH HOH A . 
I 4 HOH 72  472 431 HOH HOH A . 
I 4 HOH 73  473 522 HOH HOH A . 
I 4 HOH 74  474 553 HOH HOH A . 
I 4 HOH 75  475 530 HOH HOH A . 
I 4 HOH 76  476 511 HOH HOH A . 
I 4 HOH 77  477 485 HOH HOH A . 
I 4 HOH 78  478 483 HOH HOH A . 
I 4 HOH 79  479 455 HOH HOH A . 
I 4 HOH 80  480 502 HOH HOH A . 
I 4 HOH 81  481 493 HOH HOH A . 
I 4 HOH 82  482 482 HOH HOH A . 
I 4 HOH 83  483 27  HOH HOH A . 
I 4 HOH 84  484 495 HOH HOH A . 
I 4 HOH 85  485 532 HOH HOH A . 
I 4 HOH 86  486 466 HOH HOH A . 
I 4 HOH 87  487 546 HOH HOH A . 
I 4 HOH 88  488 433 HOH HOH A . 
I 4 HOH 89  489 524 HOH HOH A . 
I 4 HOH 90  490 76  HOH HOH A . 
I 4 HOH 91  491 8   HOH HOH A . 
I 4 HOH 92  492 57  HOH HOH A . 
I 4 HOH 93  493 29  HOH HOH A . 
I 4 HOH 94  494 542 HOH HOH A . 
I 4 HOH 95  495 536 HOH HOH A . 
I 4 HOH 96  496 494 HOH HOH A . 
I 4 HOH 97  497 550 HOH HOH A . 
I 4 HOH 98  498 445 HOH HOH A . 
I 4 HOH 99  499 507 HOH HOH A . 
I 4 HOH 100 500 527 HOH HOH A . 
I 4 HOH 101 501 402 HOH HOH A . 
I 4 HOH 102 502 67  HOH HOH A . 
I 4 HOH 103 503 625 HOH HOH A . 
I 4 HOH 104 504 484 HOH HOH A . 
I 4 HOH 105 505 545 HOH HOH A . 
I 4 HOH 106 506 571 HOH HOH A . 
I 4 HOH 107 507 554 HOH HOH A . 
I 4 HOH 108 508 560 HOH HOH A . 
I 4 HOH 109 509 535 HOH HOH A . 
I 4 HOH 110 510 640 HOH HOH A . 
I 4 HOH 111 511 556 HOH HOH A . 
I 4 HOH 112 512 429 HOH HOH A . 
I 4 HOH 113 513 501 HOH HOH A . 
I 4 HOH 114 514 562 HOH HOH A . 
I 4 HOH 115 515 14  HOH HOH A . 
I 4 HOH 116 516 580 HOH HOH A . 
I 4 HOH 117 517 492 HOH HOH A . 
I 4 HOH 118 518 526 HOH HOH A . 
I 4 HOH 119 519 86  HOH HOH A . 
I 4 HOH 120 520 569 HOH HOH A . 
I 4 HOH 121 521 572 HOH HOH A . 
I 4 HOH 122 522 437 HOH HOH A . 
I 4 HOH 123 523 551 HOH HOH A . 
I 4 HOH 124 524 583 HOH HOH A . 
I 4 HOH 125 525 576 HOH HOH A . 
I 4 HOH 126 526 653 HOH HOH A . 
I 4 HOH 127 527 594 HOH HOH A . 
I 4 HOH 128 528 582 HOH HOH A . 
I 4 HOH 129 529 595 HOH HOH A . 
I 4 HOH 130 530 588 HOH HOH A . 
I 4 HOH 131 531 597 HOH HOH A . 
J 4 HOH 1   601 415 HOH HOH B . 
J 4 HOH 2   602 614 HOH HOH B . 
J 4 HOH 3   603 563 HOH HOH B . 
J 4 HOH 4   604 508 HOH HOH B . 
J 4 HOH 5   605 521 HOH HOH B . 
J 4 HOH 6   606 547 HOH HOH B . 
J 4 HOH 7   607 570 HOH HOH B . 
J 4 HOH 8   608 12  HOH HOH B . 
J 4 HOH 9   609 524 HOH HOH B . 
J 4 HOH 10  610 622 HOH HOH B . 
J 4 HOH 11  611 545 HOH HOH B . 
J 4 HOH 12  612 643 HOH HOH B . 
J 4 HOH 13  613 576 HOH HOH B . 
J 4 HOH 14  614 534 HOH HOH B . 
J 4 HOH 15  615 523 HOH HOH B . 
J 4 HOH 16  616 555 HOH HOH B . 
J 4 HOH 17  617 535 HOH HOH B . 
J 4 HOH 18  618 507 HOH HOH B . 
J 4 HOH 19  619 593 HOH HOH B . 
J 4 HOH 20  620 510 HOH HOH B . 
J 4 HOH 21  621 562 HOH HOH B . 
J 4 HOH 22  622 568 HOH HOH B . 
J 4 HOH 23  623 611 HOH HOH B . 
J 4 HOH 24  624 537 HOH HOH B . 
J 4 HOH 25  625 522 HOH HOH B . 
J 4 HOH 26  626 572 HOH HOH B . 
J 4 HOH 27  627 55  HOH HOH B . 
J 4 HOH 28  628 506 HOH HOH B . 
J 4 HOH 29  629 548 HOH HOH B . 
J 4 HOH 30  630 585 HOH HOH B . 
J 4 HOH 31  631 618 HOH HOH B . 
J 4 HOH 32  632 584 HOH HOH B . 
J 4 HOH 33  633 607 HOH HOH B . 
J 4 HOH 34  634 511 HOH HOH B . 
J 4 HOH 35  635 596 HOH HOH B . 
J 4 HOH 36  636 571 HOH HOH B . 
J 4 HOH 37  637 525 HOH HOH B . 
J 4 HOH 38  638 639 HOH HOH B . 
J 4 HOH 39  639 561 HOH HOH B . 
J 4 HOH 40  640 532 HOH HOH B . 
J 4 HOH 41  641 558 HOH HOH B . 
J 4 HOH 42  642 556 HOH HOH B . 
J 4 HOH 43  643 659 HOH HOH B . 
J 4 HOH 44  644 526 HOH HOH B . 
J 4 HOH 45  645 538 HOH HOH B . 
J 4 HOH 46  646 564 HOH HOH B . 
J 4 HOH 47  647 505 HOH HOH B . 
J 4 HOH 48  648 589 HOH HOH B . 
J 4 HOH 49  649 87  HOH HOH B . 
J 4 HOH 50  650 569 HOH HOH B . 
J 4 HOH 51  651 512 HOH HOH B . 
J 4 HOH 52  652 619 HOH HOH B . 
J 4 HOH 53  653 628 HOH HOH B . 
J 4 HOH 54  654 552 HOH HOH B . 
J 4 HOH 55  655 543 HOH HOH B . 
J 4 HOH 56  656 546 HOH HOH B . 
J 4 HOH 57  657 579 HOH HOH B . 
J 4 HOH 58  658 608 HOH HOH B . 
J 4 HOH 59  659 600 HOH HOH B . 
J 4 HOH 60  660 574 HOH HOH B . 
J 4 HOH 61  661 597 HOH HOH B . 
J 4 HOH 62  662 595 HOH HOH B . 
J 4 HOH 63  663 566 HOH HOH B . 
J 4 HOH 64  664 520 HOH HOH B . 
J 4 HOH 65  665 601 HOH HOH B . 
J 4 HOH 66  666 530 HOH HOH B . 
J 4 HOH 67  667 516 HOH HOH B . 
J 4 HOH 68  668 582 HOH HOH B . 
J 4 HOH 69  669 644 HOH HOH B . 
J 4 HOH 70  670 34  HOH HOH B . 
J 4 HOH 71  671 599 HOH HOH B . 
J 4 HOH 72  672 538 HOH HOH B . 
J 4 HOH 73  673 632 HOH HOH B . 
J 4 HOH 74  674 656 HOH HOH B . 
J 4 HOH 75  675 615 HOH HOH B . 
J 4 HOH 76  676 567 HOH HOH B . 
J 4 HOH 77  677 638 HOH HOH B . 
J 4 HOH 78  678 624 HOH HOH B . 
J 4 HOH 79  679 609 HOH HOH B . 
J 4 HOH 80  680 577 HOH HOH B . 
J 4 HOH 81  681 633 HOH HOH B . 
J 4 HOH 82  682 630 HOH HOH B . 
J 4 HOH 83  683 18  HOH HOH B . 
J 4 HOH 84  684 528 HOH HOH B . 
J 4 HOH 85  685 602 HOH HOH B . 
J 4 HOH 86  686 627 HOH HOH B . 
J 4 HOH 87  687 590 HOH HOH B . 
J 4 HOH 88  688 629 HOH HOH B . 
J 4 HOH 89  689 592 HOH HOH B . 
J 4 HOH 90  690 637 HOH HOH B . 
J 4 HOH 91  691 612 HOH HOH B . 
J 4 HOH 92  692 636 HOH HOH B . 
J 4 HOH 93  693 605 HOH HOH B . 
J 4 HOH 94  694 581 HOH HOH B . 
J 4 HOH 95  695 560 HOH HOH B . 
J 4 HOH 96  696 617 HOH HOH B . 
J 4 HOH 97  697 442 HOH HOH B . 
J 4 HOH 98  698 587 HOH HOH B . 
J 4 HOH 99  699 529 HOH HOH B . 
J 4 HOH 100 700 598 HOH HOH B . 
J 4 HOH 101 701 529 HOH HOH B . 
J 4 HOH 102 702 650 HOH HOH B . 
J 4 HOH 103 703 641 HOH HOH B . 
J 4 HOH 104 704 550 HOH HOH B . 
J 4 HOH 105 705 620 HOH HOH B . 
J 4 HOH 106 706 539 HOH HOH B . 
J 4 HOH 107 707 646 HOH HOH B . 
J 4 HOH 108 708 586 HOH HOH B . 
J 4 HOH 109 709 657 HOH HOH B . 
J 4 HOH 110 710 649 HOH HOH B . 
J 4 HOH 111 711 635 HOH HOH B . 
J 4 HOH 112 712 588 HOH HOH B . 
J 4 HOH 113 713 623 HOH HOH B . 
J 4 HOH 114 714 662 HOH HOH B . 
J 4 HOH 115 715 665 HOH HOH B . 
J 4 HOH 116 716 631 HOH HOH B . 
J 4 HOH 117 717 667 HOH HOH B . 
J 4 HOH 118 718 671 HOH HOH B . 
J 4 HOH 119 719 673 HOH HOH B . 
J 4 HOH 120 720 81  HOH HOH B . 
J 4 HOH 121 721 676 HOH HOH B . 
J 4 HOH 122 722 675 HOH HOH B . 
J 4 HOH 123 723 678 HOH HOH B . 
J 4 HOH 124 724 672 HOH HOH B . 
J 4 HOH 125 725 680 HOH HOH B . 
J 4 HOH 126 726 677 HOH HOH B . 
K 4 HOH 1   601 418 HOH HOH C . 
K 4 HOH 2   602 403 HOH HOH C . 
K 4 HOH 3   603 407 HOH HOH C . 
K 4 HOH 4   604 435 HOH HOH C . 
K 4 HOH 5   605 43  HOH HOH C . 
K 4 HOH 6   606 3   HOH HOH C . 
K 4 HOH 7   607 440 HOH HOH C . 
K 4 HOH 8   608 450 HOH HOH C . 
K 4 HOH 9   609 439 HOH HOH C . 
K 4 HOH 10  610 94  HOH HOH C . 
K 4 HOH 11  611 433 HOH HOH C . 
K 4 HOH 12  612 425 HOH HOH C . 
K 4 HOH 13  613 458 HOH HOH C . 
K 4 HOH 14  614 51  HOH HOH C . 
K 4 HOH 15  615 445 HOH HOH C . 
K 4 HOH 16  616 62  HOH HOH C . 
K 4 HOH 17  617 412 HOH HOH C . 
K 4 HOH 18  618 424 HOH HOH C . 
K 4 HOH 19  619 408 HOH HOH C . 
K 4 HOH 20  620 428 HOH HOH C . 
K 4 HOH 21  621 414 HOH HOH C . 
K 4 HOH 22  622 405 HOH HOH C . 
K 4 HOH 23  623 526 HOH HOH C . 
K 4 HOH 24  624 410 HOH HOH C . 
K 4 HOH 25  625 430 HOH HOH C . 
K 4 HOH 26  626 438 HOH HOH C . 
K 4 HOH 27  627 422 HOH HOH C . 
K 4 HOH 28  628 401 HOH HOH C . 
K 4 HOH 29  629 434 HOH HOH C . 
K 4 HOH 30  630 47  HOH HOH C . 
K 4 HOH 31  631 426 HOH HOH C . 
K 4 HOH 32  632 448 HOH HOH C . 
K 4 HOH 33  633 419 HOH HOH C . 
K 4 HOH 34  634 92  HOH HOH C . 
K 4 HOH 35  635 22  HOH HOH C . 
K 4 HOH 36  636 423 HOH HOH C . 
K 4 HOH 37  637 427 HOH HOH C . 
K 4 HOH 38  638 60  HOH HOH C . 
K 4 HOH 39  639 464 HOH HOH C . 
K 4 HOH 40  640 406 HOH HOH C . 
K 4 HOH 41  641 465 HOH HOH C . 
K 4 HOH 42  642 61  HOH HOH C . 
K 4 HOH 43  643 460 HOH HOH C . 
K 4 HOH 44  644 96  HOH HOH C . 
K 4 HOH 45  645 56  HOH HOH C . 
K 4 HOH 46  646 558 HOH HOH C . 
K 4 HOH 47  647 509 HOH HOH C . 
K 4 HOH 48  648 70  HOH HOH C . 
K 4 HOH 49  649 26  HOH HOH C . 
K 4 HOH 50  650 453 HOH HOH C . 
K 4 HOH 51  651 404 HOH HOH C . 
K 4 HOH 52  652 454 HOH HOH C . 
K 4 HOH 53  653 432 HOH HOH C . 
K 4 HOH 54  654 20  HOH HOH C . 
K 4 HOH 55  655 37  HOH HOH C . 
K 4 HOH 56  656 459 HOH HOH C . 
K 4 HOH 57  657 449 HOH HOH C . 
K 4 HOH 58  658 451 HOH HOH C . 
K 4 HOH 59  659 429 HOH HOH C . 
K 4 HOH 60  660 41  HOH HOH C . 
K 4 HOH 61  661 452 HOH HOH C . 
K 4 HOH 62  662 477 HOH HOH C . 
K 4 HOH 63  663 95  HOH HOH C . 
K 4 HOH 64  664 28  HOH HOH C . 
K 4 HOH 65  665 446 HOH HOH C . 
K 4 HOH 66  666 32  HOH HOH C . 
K 4 HOH 67  667 468 HOH HOH C . 
K 4 HOH 68  668 616 HOH HOH C . 
K 4 HOH 69  669 13  HOH HOH C . 
K 4 HOH 70  670 462 HOH HOH C . 
K 4 HOH 71  671 415 HOH HOH C . 
K 4 HOH 72  672 42  HOH HOH C . 
K 4 HOH 73  673 455 HOH HOH C . 
K 4 HOH 74  674 559 HOH HOH C . 
K 4 HOH 75  675 475 HOH HOH C . 
K 4 HOH 76  676 572 HOH HOH C . 
K 4 HOH 77  677 473 HOH HOH C . 
L 4 HOH 1   501 521 HOH HOH D . 
L 4 HOH 2   502 534 HOH HOH D . 
L 4 HOH 3   503 501 HOH HOH D . 
L 4 HOH 4   504 66  HOH HOH D . 
L 4 HOH 5   505 508 HOH HOH D . 
L 4 HOH 6   506 567 HOH HOH D . 
L 4 HOH 7   507 532 HOH HOH D . 
L 4 HOH 8   508 524 HOH HOH D . 
L 4 HOH 9   509 65  HOH HOH D . 
L 4 HOH 10  510 522 HOH HOH D . 
L 4 HOH 11  511 555 HOH HOH D . 
L 4 HOH 12  512 512 HOH HOH D . 
L 4 HOH 13  513 49  HOH HOH D . 
L 4 HOH 14  514 506 HOH HOH D . 
L 4 HOH 15  515 529 HOH HOH D . 
L 4 HOH 16  516 547 HOH HOH D . 
L 4 HOH 17  517 539 HOH HOH D . 
L 4 HOH 18  518 530 HOH HOH D . 
L 4 HOH 19  519 513 HOH HOH D . 
L 4 HOH 20  520 45  HOH HOH D . 
L 4 HOH 21  521 82  HOH HOH D . 
L 4 HOH 22  522 511 HOH HOH D . 
L 4 HOH 23  523 527 HOH HOH D . 
L 4 HOH 24  524 543 HOH HOH D . 
L 4 HOH 25  525 523 HOH HOH D . 
L 4 HOH 26  526 68  HOH HOH D . 
L 4 HOH 27  527 40  HOH HOH D . 
L 4 HOH 28  528 520 HOH HOH D . 
L 4 HOH 29  529 533 HOH HOH D . 
L 4 HOH 30  530 505 HOH HOH D . 
L 4 HOH 31  531 78  HOH HOH D . 
L 4 HOH 32  532 540 HOH HOH D . 
L 4 HOH 33  533 514 HOH HOH D . 
L 4 HOH 34  534 554 HOH HOH D . 
L 4 HOH 35  535 50  HOH HOH D . 
L 4 HOH 36  536 503 HOH HOH D . 
L 4 HOH 37  537 504 HOH HOH D . 
L 4 HOH 38  538 507 HOH HOH D . 
L 4 HOH 39  539 33  HOH HOH D . 
L 4 HOH 40  540 46  HOH HOH D . 
L 4 HOH 41  541 52  HOH HOH D . 
L 4 HOH 42  542 553 HOH HOH D . 
L 4 HOH 43  543 565 HOH HOH D . 
L 4 HOH 44  544 54  HOH HOH D . 
L 4 HOH 45  545 84  HOH HOH D . 
L 4 HOH 46  546 550 HOH HOH D . 
L 4 HOH 47  547 561 HOH HOH D . 
L 4 HOH 48  548 544 HOH HOH D . 
L 4 HOH 49  549 557 HOH HOH D . 
L 4 HOH 50  550 562 HOH HOH D . 
L 4 HOH 51  551 538 HOH HOH D . 
L 4 HOH 52  552 560 HOH HOH D . 
L 4 HOH 53  553 36  HOH HOH D . 
L 4 HOH 54  554 552 HOH HOH D . 
L 4 HOH 55  555 568 HOH HOH D . 
L 4 HOH 56  556 575 HOH HOH D . 
L 4 HOH 57  557 551 HOH HOH D . 
L 4 HOH 58  558 474 HOH HOH D . 
L 4 HOH 59  559 571 HOH HOH D . 
L 4 HOH 60  560 579 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ET2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     73.839 
_cell.length_a_esd                 ? 
_cell.length_b                     132.986 
_cell.length_b_esd                 ? 
_cell.length_c                     146.871 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ET2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ET2 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.77 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.53 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ET2 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.37 
_reflns.d_resolution_low                               146.87 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     57408 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           96.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.993 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.351 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
10.33 146.87 ? 21.8 ? ? ? ? 829  ? ? ? ? ? ? ? ? ? ? ? 12   ? ? ? ? ? ? 1 1 0.998 ? ? 99.8 ? 0.07  ? ? ? ? ? ? ? ? ? 
2.37  2.43   ? 1    ? ? ? ? 4479 ? ? ? ? ? ? ? ? ? ? ? 13.5 ? ? ? ? ? ? 2 1 0.411 ? ? 99.1 ? 2.975 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -0.970 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.287 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.683 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               32.522 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.938 
_refine.correlation_coeff_Fo_to_Fc_free          0.940 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ET2 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.370 
_refine.ls_d_res_low                             98.774 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     53447 
_refine.ls_number_reflns_R_free                  2699 
_refine.ls_number_reflns_R_work                  50748 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    89.856 
_refine.ls_percent_reflns_R_free                 5.050 
_refine.ls_R_factor_all                          0.229 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2306 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2290 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.221 
_refine.ls_wR_factor_R_work                      0.222 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.494 
_refine.pdbx_overall_ESU_R_Free                  0.249 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9470 
_refine.pdbx_average_fsc_free                    0.9465 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.370 
_refine_hist.d_res_low                        98.774 
_refine_hist.number_atoms_solvent             394 
_refine_hist.number_atoms_total               9461 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9023 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         44 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  9333  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.616  1.848  12683 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.261  5.000  1124  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 20.211 5.000  55    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.930 10.000 1623  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.638 10.000 404   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.101  0.200  1431  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  7014  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.228  0.200  4623  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.317  0.200  6378  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.150  0.200  485   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.262  0.200  81    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.347  0.200  12    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.839  3.085  4499  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.594  5.538  5622  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.952  3.345  4834  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.087  6.004  7061  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.855  35.244 14549 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.370  2.432  4307 . 13  351  8.4514  . 2.723 . . 2.726 . . . . . 2.749 . 20 . 0.626 0.494 2.649 
'X-RAY DIFFRACTION' 2.432  2.498  4232 . 218 3959 98.7004 . 0.741 . . 0.739 . . . . . 0.842 . 20 . 0.817 0.817 0.779 
'X-RAY DIFFRACTION' 2.498  2.571  4135 . 220 3870 98.9117 . 0.416 . . 0.415 . . . . . 0.420 . 20 . 0.903 0.909 0.437 
'X-RAY DIFFRACTION' 2.571  2.650  4002 . 169 3756 98.0760 . 0.322 . . 0.321 . . . . . 0.325 . 20 . 0.934 0.926 0.334 
'X-RAY DIFFRACTION' 2.650  2.736  3869 . 98  2068 55.9835 . 0.289 . . 0.289 . . . . . 0.289 . 20 . 0.946 0.943 0.285 
'X-RAY DIFFRACTION' 2.736  2.832  3773 . 210 3528 99.0724 . 0.272 . . 0.272 . . . . . 0.268 . 20 . 0.950 0.952 0.283 
'X-RAY DIFFRACTION' 2.832  2.939  3643 . 166 3447 99.1765 . 0.266 . . 0.266 . . . . . 0.260 . 20 . 0.953 0.954 0.265 
'X-RAY DIFFRACTION' 2.939  3.059  3504 . 168 3312 99.3151 . 0.257 . . 0.256 . . . . . 0.248 . 20 . 0.962 0.953 0.273 
'X-RAY DIFFRACTION' 3.059  3.195  3348 . 193 3133 99.3429 . 0.254 . . 0.254 . . . . . 0.246 . 20 . 0.962 0.966 0.245 
'X-RAY DIFFRACTION' 3.195  3.351  3219 . 144 3058 99.4719 . 0.235 . . 0.235 . . . . . 0.227 . 20 . 0.969 0.968 0.246 
'X-RAY DIFFRACTION' 3.351  3.532  3071 . 159 2897 99.5116 . 0.216 . . 0.215 . . . . . 0.209 . 20 . 0.975 0.971 0.233 
'X-RAY DIFFRACTION' 3.532  3.746  2904 . 164 2729 99.6212 . 0.202 . . 0.201 . . . . . 0.196 . 20 . 0.977 0.976 0.210 
'X-RAY DIFFRACTION' 3.746  4.004  2739 . 139 2586 99.4889 . 0.194 . . 0.194 . . . . . 0.189 . 20 . 0.978 0.979 0.192 
'X-RAY DIFFRACTION' 4.004  4.324  2580 . 136 2433 99.5736 . 0.174 . . 0.175 . . . . . 0.172 . 20 . 0.982 0.986 0.158 
'X-RAY DIFFRACTION' 4.324  4.736  2360 . 120 2232 99.6610 . 0.168 . . 0.168 . . . . . 0.168 . 20 . 0.983 0.984 0.169 
'X-RAY DIFFRACTION' 4.736  5.293  2162 . 112 2045 99.7687 . 0.177 . . 0.177 . . . . . 0.178 . 20 . 0.982 0.983 0.177 
'X-RAY DIFFRACTION' 5.293  6.109  1908 . 93  1811 99.7904 . 0.207 . . 0.206 . . . . . 0.203 . 20 . 0.979 0.970 0.235 
'X-RAY DIFFRACTION' 6.109  7.475  1645 . 80  1561 99.7568 . 0.219 . . 0.222 . . . . . 0.221 . 20 . 0.978 0.986 0.165 
'X-RAY DIFFRACTION' 7.475  10.542 1303 . 64  1235 99.6930 . 0.151 . . 0.150 . . . . . 0.161 . 20 . 0.987 0.984 0.164 
'X-RAY DIFFRACTION' 10.542 98.774 773  . 33  737  99.6119 . 0.219 . . 0.218 . . . . . 0.297 . 20 . 0.965 0.975 0.250 
# 
_struct.entry_id                     9ET2 
_struct.title                        'CDK2-cyclin A in complex with FragLite 11' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ET2 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CDK2_HUMAN  P24941 ? 1 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
2 UNP CCNA2_BOVIN P30274 ? 2 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ET2 A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
2 2 9ET2 B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
3 1 9ET2 C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
4 2 9ET2 D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ET2 GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  1  
1 9ET2 PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  2  
1 9ET2 GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  3  
1 9ET2 SER A 4   ? UNP P24941 ? ? 'expression tag' 0   4  
2 9ET2 GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 5  
2 9ET2 HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 6  
2 9ET2 HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 7  
2 9ET2 HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 8  
2 9ET2 HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 9  
2 9ET2 HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 10 
2 9ET2 HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 11 
3 9ET2 GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  12 
3 9ET2 PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  13 
3 9ET2 GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  14 
3 9ET2 SER C 4   ? UNP P24941 ? ? 'expression tag' 0   15 
4 9ET2 GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 16 
4 9ET2 HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 17 
4 9ET2 HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 18 
4 9ET2 HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 19 
4 9ET2 HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 20 
4 9ET2 HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 21 
4 9ET2 HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3460  ? 
1 MORE         -15   ? 
1 'SSA (A^2)'  23420 ? 
2 'ABSA (A^2)' 3600  ? 
2 MORE         -18   ? 
2 'SSA (A^2)'  23370 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,G,I,J 
2 1 C,D,H,K,L     
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 4   ? GLU A 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P2  AA2 PRO A 49  ? LEU A 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 91  ? SER A 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P4  AA4 PRO A 104 ? HIS A 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P5  AA5 LYS A 133 ? GLN A 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P6  AA6 THR A 169 ? ARG A 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P7  AA7 ALA A 174 ? LEU A 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P8  AA8 THR A 186 ? ARG A 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P9  AA9 SER A 211 ? GLY A 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P10 AB1 GLY A 233 ? MET A 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P11 AB2 ASP A 251 ? VAL A 255 ? ASP A 247 VAL A 251 5 ? 5  
HELX_P HELX_P12 AB3 ASP A 260 ? LEU A 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P13 AB4 SER A 280 ? LEU A 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P14 AB5 ALA A 286 ? GLN A 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P15 AB6 GLY B 1   ? VAL B 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P16 AB7 TYR B 8   ? CYS B 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P17 AB8 TYR B 29  ? GLN B 33  ? TYR B 199 GLN B 203 5 ? 5  
HELX_P HELX_P18 AB9 THR B 37  ? TYR B 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P19 AC1 GLN B 58  ? SER B 74  ? GLN B 228 SER B 244 1 ? 17 
HELX_P HELX_P20 AC2 LEU B 79  ? GLY B 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P21 AC3 LYS B 82  ? GLU B 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P22 AC4 GLU B 104 ? THR B 112 ? GLU B 274 THR B 282 1 ? 9  
HELX_P HELX_P23 AC5 THR B 117 ? ALA B 133 ? THR B 287 ALA B 303 1 ? 17 
HELX_P HELX_P24 AC6 THR B 140 ? PHE B 149 ? THR B 310 PHE B 319 1 ? 10 
HELX_P HELX_P25 AC7 LEU B 150 ? GLN B 152 ? LEU B 320 GLN B 322 5 ? 3  
HELX_P HELX_P26 AC8 ASN B 156 ? ASP B 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P27 AC9 ASP B 173 ? LEU B 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P28 AD1 LEU B 181 ? GLY B 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P29 AD2 PRO B 203 ? GLY B 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P30 AD3 THR B 213 ? ALA B 231 ? THR B 383 ALA B 401 1 ? 19 
HELX_P HELX_P31 AD4 GLN B 237 ? TYR B 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P32 AD5 LYS B 244 ? HIS B 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P33 AD6 GLY B 250 ? LEU B 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P34 AD7 PRO C 49  ? GLU C 61  ? PRO C 45  GLU C 57  1 ? 13 
HELX_P HELX_P35 AD8 LEU C 91  ? SER C 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P36 AD9 PRO C 104 ? SER C 124 ? PRO C 100 SER C 120 1 ? 21 
HELX_P HELX_P37 AE1 LYS C 133 ? GLN C 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P38 AE2 THR C 169 ? ARG C 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P39 AE3 ALA C 174 ? LEU C 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P40 AE4 THR C 186 ? ARG C 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P41 AE5 SER C 211 ? GLY C 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P42 AE6 ASP C 251 ? VAL C 256 ? ASP C 247 VAL C 252 1 ? 6  
HELX_P HELX_P43 AE7 ASP C 260 ? LEU C 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P44 AE8 SER C 280 ? ALA C 286 ? SER C 276 ALA C 282 1 ? 7  
HELX_P HELX_P45 AE9 HIS C 287 ? GLN C 291 ? HIS C 283 GLN C 287 5 ? 5  
HELX_P HELX_P46 AF1 GLY D 1   ? VAL D 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P47 AF2 TYR D 8   ? CYS D 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P48 AF3 GLY D 28  ? GLN D 33  ? GLY D 198 GLN D 203 5 ? 6  
HELX_P HELX_P49 AF4 THR D 37  ? TYR D 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P50 AF5 GLN D 58  ? SER D 74  ? GLN D 228 SER D 244 1 ? 17 
HELX_P HELX_P51 AF6 LEU D 79  ? GLY D 81  ? LEU D 249 GLY D 251 5 ? 3  
HELX_P HELX_P52 AF7 LYS D 82  ? GLU D 99  ? LYS D 252 GLU D 269 1 ? 18 
HELX_P HELX_P53 AF8 GLU D 104 ? THR D 112 ? GLU D 274 THR D 282 1 ? 9  
HELX_P HELX_P54 AF9 THR D 117 ? LEU D 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P55 AG1 THR D 140 ? LEU D 150 ? THR D 310 LEU D 320 1 ? 11 
HELX_P HELX_P56 AG2 ASN D 156 ? ASP D 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P57 AG3 ASP D 173 ? LEU D 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P58 AG4 LEU D 181 ? GLY D 199 ? LEU D 351 GLY D 369 1 ? 19 
HELX_P HELX_P59 AG5 PRO D 203 ? GLY D 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P60 AG6 THR D 213 ? ALA D 231 ? THR D 383 ALA D 401 1 ? 19 
HELX_P HELX_P61 AG7 PRO D 232 ? HIS D 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P62 AG8 GLN D 237 ? TYR D 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P63 AG9 LYS D 244 ? HIS D 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P64 AH1 GLY D 250 ? LEU D 254 ? GLY D 420 LEU D 424 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A TYR 163 C ? ? ? 1_555 A TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale2 covale both ? A TPO 164 C ? ? ? 1_555 A HIS 165 N A ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.338 ? ? 
covale3 covale both ? A TPO 164 C ? ? ? 1_555 A HIS 165 N B ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.343 ? ? 
covale4 covale both ? C TYR 163 C ? ? ? 1_555 C TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.337 ? ? 
covale5 covale both ? C TPO 164 C ? ? ? 1_555 C HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.342 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO A 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO C 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 158 A . ? VAL 154 A PRO 159 A ? PRO 155 A 1 -8.83 
2 GLN 153 B . ? GLN 323 B PRO 154 B ? PRO 324 B 1 -7.97 
3 ASP 175 B . ? ASP 345 B PRO 176 B ? PRO 346 B 1 14.81 
4 VAL 158 C . ? VAL 154 C PRO 159 C ? PRO 155 C 1 -7.85 
5 GLN 153 D . ? GLN 323 D PRO 154 D ? PRO 324 D 1 10.99 
6 ASP 175 D . ? ASP 345 D PRO 176 D ? PRO 346 D 1 9.43  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 8   ? GLY A 15  ? PHE A 4   GLY A 11  
AA1 2 VAL A 22  ? ASN A 27  ? VAL A 18  ASN A 23  
AA1 3 VAL A 33  ? ARG A 40  ? VAL A 29  ARG A 36  
AA1 4 LYS A 79  ? GLU A 85  ? LYS A 75  GLU A 81  
AA1 5 LEU A 70  ? HIS A 75  ? LEU A 66  HIS A 71  
AA2 1 GLN A 89  ? ASP A 90  ? GLN A 85  ASP A 86  
AA2 2 LEU A 137 ? ILE A 139 ? LEU A 133 ILE A 135 
AA2 3 ILE A 145 ? LEU A 147 ? ILE A 141 LEU A 143 
AA3 1 VAL A 127 ? LEU A 128 ? VAL A 123 LEU A 124 
AA3 2 ARG A 154 ? ALA A 155 ? ARG A 150 ALA A 151 
AA4 1 PHE C 8   ? GLY C 17  ? PHE C 4   GLY C 13  
AA4 2 GLY C 20  ? ASN C 27  ? GLY C 16  ASN C 23  
AA4 3 VAL C 33  ? ARG C 40  ? VAL C 29  ARG C 36  
AA4 4 LYS C 79  ? GLU C 85  ? LYS C 75  GLU C 81  
AA4 5 LEU C 70  ? HIS C 75  ? LEU C 66  HIS C 71  
AA5 1 GLN C 89  ? ASP C 90  ? GLN C 85  ASP C 86  
AA5 2 LEU C 137 ? ILE C 139 ? LEU C 133 ILE C 135 
AA5 3 ILE C 145 ? LEU C 147 ? ILE C 141 LEU C 143 
AA6 1 VAL C 127 ? LEU C 128 ? VAL C 123 LEU C 124 
AA6 2 ARG C 154 ? ALA C 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 12  ? N GLU A 8   O LYS A 24  ? O LYS A 20  
AA1 2 3 N ALA A 25  ? N ALA A 21  O VAL A 34  ? O VAL A 30  
AA1 3 4 N ILE A 39  ? N ILE A 35  O LEU A 80  ? O LEU A 76  
AA1 4 5 O TYR A 81  ? O TYR A 77  N ILE A 74  ? N ILE A 70  
AA2 1 2 N GLN A 89  ? N GLN A 85  O ILE A 139 ? O ILE A 135 
AA2 2 3 N LEU A 138 ? N LEU A 134 O LYS A 146 ? O LYS A 142 
AA3 1 2 N LEU A 128 ? N LEU A 124 O ARG A 154 ? O ARG A 150 
AA4 1 2 N ILE C 14  ? N ILE C 10  O VAL C 22  ? O VAL C 18  
AA4 2 3 N ALA C 25  ? N ALA C 21  O VAL C 34  ? O VAL C 30  
AA4 3 4 N ILE C 39  ? N ILE C 35  O LEU C 80  ? O LEU C 76  
AA4 4 5 O TYR C 81  ? O TYR C 77  N ILE C 74  ? N ILE C 70  
AA5 1 2 N GLN C 89  ? N GLN C 85  O ILE C 139 ? O ILE C 135 
AA5 2 3 N LEU C 138 ? N LEU C 134 O LYS C 146 ? O LYS C 142 
AA6 1 2 N LEU C 128 ? N LEU C 124 O ARG C 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ET2 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             B 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             B 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             B 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                89.66 
_pdbx_validate_rmsd_angle.angle_target_value         102.60 
_pdbx_validate_rmsd_angle.angle_deviation            -12.94 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR A 72  ? ? -102.65 -145.95 
2  1 ASN A 74  ? ? 38.49   31.55   
3  1 ASP A 127 ? ? -159.79 44.01   
4  1 ASP A 145 ? ? 57.73   90.30   
5  1 TYR A 159 ? ? -113.17 -168.67 
6  1 VAL A 164 ? ? 78.45   121.77  
7  1 SER A 181 ? ? -147.17 -159.18 
8  1 ARG A 297 ? ? 83.14   146.12  
9  1 VAL B 175 ? ? 28.92   68.24   
10 1 LYS B 226 ? ? 38.80   50.52   
11 1 TRP B 372 ? ? -35.14  113.05  
12 1 THR C 41  ? ? -131.79 -81.45  
13 1 LEU C 83  ? ? -99.00  -77.69  
14 1 HIS C 84  ? ? -170.83 -59.15  
15 1 ARG C 126 ? ? 80.25   0.88    
16 1 ASP C 127 ? ? -142.10 41.73   
17 1 ASP C 145 ? ? 43.80   86.79   
18 1 TYR C 159 ? ? -115.40 -167.01 
19 1 VAL C 164 ? ? 78.61   126.17  
20 1 LYS C 242 ? ? -106.61 72.72   
21 1 VAL D 175 ? ? 30.47   66.99   
22 1 LYS D 226 ? ? 37.63   54.78   
23 1 GLN D 323 ? ? -153.27 86.85   
24 1 TRP D 372 ? ? -26.41  115.71  
25 1 PRO D 402 ? ? -49.85  -18.01  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 150 ? ? 0.214 'SIDE CHAIN' 
2  1 ARG A 157 ? ? 0.219 'SIDE CHAIN' 
3  1 ARG A 214 ? ? 0.158 'SIDE CHAIN' 
4  1 ARG A 217 ? ? 0.113 'SIDE CHAIN' 
5  1 ARG B 187 ? ? 0.112 'SIDE CHAIN' 
6  1 ARG B 241 ? ? 0.161 'SIDE CHAIN' 
7  1 ARG B 293 ? ? 0.215 'SIDE CHAIN' 
8  1 ARG C 36  ? ? 0.294 'SIDE CHAIN' 
9  1 ARG C 157 ? ? 0.159 'SIDE CHAIN' 
10 1 ARG D 187 ? ? 0.110 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 A TPO 164 A TPO 160 ? THR 'modified residue' 
2 C TPO 164 C TPO 160 ? THR 'modified residue' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 B VAL 432 ? B VAL 262 
2  1 Y 1 B HIS 433 ? B HIS 263 
3  1 Y 1 B HIS 434 ? B HIS 264 
4  1 Y 1 B HIS 435 ? B HIS 265 
5  1 Y 1 B HIS 436 ? B HIS 266 
6  1 Y 1 B HIS 437 ? B HIS 267 
7  1 Y 1 B HIS 438 ? B HIS 268 
8  1 Y 1 C GLY -3  ? C GLY 1   
9  1 Y 1 C PRO -2  ? C PRO 2   
10 1 Y 1 C GLY -1  ? C GLY 3   
11 1 Y 1 C ARG 297 ? C ARG 301 
12 1 Y 1 C LEU 298 ? C LEU 302 
13 1 Y 1 D HIS 433 ? D HIS 263 
14 1 Y 1 D HIS 434 ? D HIS 264 
15 1 Y 1 D HIS 435 ? D HIS 265 
16 1 Y 1 D HIS 436 ? D HIS 266 
17 1 Y 1 D HIS 437 ? D HIS 267 
18 1 Y 1 D HIS 438 ? D HIS 268 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
IJX C4   C  Y N 161 
IJX C5   C  Y N 162 
IJX C6   C  Y N 163 
IJX C7   C  Y N 164 
IJX C8   C  Y N 165 
IJX N1   N  N N 166 
IJX C3   C  Y N 167 
IJX C1   C  N N 168 
IJX C2   C  N N 169 
IJX O1   O  N N 170 
IJX BR1  BR N N 171 
IJX H1   H  N N 172 
IJX H2   H  N N 173 
IJX H3   H  N N 174 
IJX H4   H  N N 175 
IJX H5   H  N N 176 
IJX H6   H  N N 177 
IJX H7   H  N N 178 
IJX H8   H  N N 179 
ILE N    N  N N 180 
ILE CA   C  N S 181 
ILE C    C  N N 182 
ILE O    O  N N 183 
ILE CB   C  N S 184 
ILE CG1  C  N N 185 
ILE CG2  C  N N 186 
ILE CD1  C  N N 187 
ILE OXT  O  N N 188 
ILE H    H  N N 189 
ILE H2   H  N N 190 
ILE HA   H  N N 191 
ILE HB   H  N N 192 
ILE HG12 H  N N 193 
ILE HG13 H  N N 194 
ILE HG21 H  N N 195 
ILE HG22 H  N N 196 
ILE HG23 H  N N 197 
ILE HD11 H  N N 198 
ILE HD12 H  N N 199 
ILE HD13 H  N N 200 
ILE HXT  H  N N 201 
LEU N    N  N N 202 
LEU CA   C  N S 203 
LEU C    C  N N 204 
LEU O    O  N N 205 
LEU CB   C  N N 206 
LEU CG   C  N N 207 
LEU CD1  C  N N 208 
LEU CD2  C  N N 209 
LEU OXT  O  N N 210 
LEU H    H  N N 211 
LEU H2   H  N N 212 
LEU HA   H  N N 213 
LEU HB2  H  N N 214 
LEU HB3  H  N N 215 
LEU HG   H  N N 216 
LEU HD11 H  N N 217 
LEU HD12 H  N N 218 
LEU HD13 H  N N 219 
LEU HD21 H  N N 220 
LEU HD22 H  N N 221 
LEU HD23 H  N N 222 
LEU HXT  H  N N 223 
LYS N    N  N N 224 
LYS CA   C  N S 225 
LYS C    C  N N 226 
LYS O    O  N N 227 
LYS CB   C  N N 228 
LYS CG   C  N N 229 
LYS CD   C  N N 230 
LYS CE   C  N N 231 
LYS NZ   N  N N 232 
LYS OXT  O  N N 233 
LYS H    H  N N 234 
LYS H2   H  N N 235 
LYS HA   H  N N 236 
LYS HB2  H  N N 237 
LYS HB3  H  N N 238 
LYS HG2  H  N N 239 
LYS HG3  H  N N 240 
LYS HD2  H  N N 241 
LYS HD3  H  N N 242 
LYS HE2  H  N N 243 
LYS HE3  H  N N 244 
LYS HZ1  H  N N 245 
LYS HZ2  H  N N 246 
LYS HZ3  H  N N 247 
LYS HXT  H  N N 248 
MET N    N  N N 249 
MET CA   C  N S 250 
MET C    C  N N 251 
MET O    O  N N 252 
MET CB   C  N N 253 
MET CG   C  N N 254 
MET SD   S  N N 255 
MET CE   C  N N 256 
MET OXT  O  N N 257 
MET H    H  N N 258 
MET H2   H  N N 259 
MET HA   H  N N 260 
MET HB2  H  N N 261 
MET HB3  H  N N 262 
MET HG2  H  N N 263 
MET HG3  H  N N 264 
MET HE1  H  N N 265 
MET HE2  H  N N 266 
MET HE3  H  N N 267 
MET HXT  H  N N 268 
PHE N    N  N N 269 
PHE CA   C  N S 270 
PHE C    C  N N 271 
PHE O    O  N N 272 
PHE CB   C  N N 273 
PHE CG   C  Y N 274 
PHE CD1  C  Y N 275 
PHE CD2  C  Y N 276 
PHE CE1  C  Y N 277 
PHE CE2  C  Y N 278 
PHE CZ   C  Y N 279 
PHE OXT  O  N N 280 
PHE H    H  N N 281 
PHE H2   H  N N 282 
PHE HA   H  N N 283 
PHE HB2  H  N N 284 
PHE HB3  H  N N 285 
PHE HD1  H  N N 286 
PHE HD2  H  N N 287 
PHE HE1  H  N N 288 
PHE HE2  H  N N 289 
PHE HZ   H  N N 290 
PHE HXT  H  N N 291 
PRO N    N  N N 292 
PRO CA   C  N S 293 
PRO C    C  N N 294 
PRO O    O  N N 295 
PRO CB   C  N N 296 
PRO CG   C  N N 297 
PRO CD   C  N N 298 
PRO OXT  O  N N 299 
PRO H    H  N N 300 
PRO HA   H  N N 301 
PRO HB2  H  N N 302 
PRO HB3  H  N N 303 
PRO HG2  H  N N 304 
PRO HG3  H  N N 305 
PRO HD2  H  N N 306 
PRO HD3  H  N N 307 
PRO HXT  H  N N 308 
SER N    N  N N 309 
SER CA   C  N S 310 
SER C    C  N N 311 
SER O    O  N N 312 
SER CB   C  N N 313 
SER OG   O  N N 314 
SER OXT  O  N N 315 
SER H    H  N N 316 
SER H2   H  N N 317 
SER HA   H  N N 318 
SER HB2  H  N N 319 
SER HB3  H  N N 320 
SER HG   H  N N 321 
SER HXT  H  N N 322 
THR N    N  N N 323 
THR CA   C  N S 324 
THR C    C  N N 325 
THR O    O  N N 326 
THR CB   C  N R 327 
THR OG1  O  N N 328 
THR CG2  C  N N 329 
THR OXT  O  N N 330 
THR H    H  N N 331 
THR H2   H  N N 332 
THR HA   H  N N 333 
THR HB   H  N N 334 
THR HG1  H  N N 335 
THR HG21 H  N N 336 
THR HG22 H  N N 337 
THR HG23 H  N N 338 
THR HXT  H  N N 339 
TPO N    N  N N 340 
TPO CA   C  N S 341 
TPO CB   C  N R 342 
TPO CG2  C  N N 343 
TPO OG1  O  N N 344 
TPO P    P  N N 345 
TPO O1P  O  N N 346 
TPO O2P  O  N N 347 
TPO O3P  O  N N 348 
TPO C    C  N N 349 
TPO O    O  N N 350 
TPO OXT  O  N N 351 
TPO H    H  N N 352 
TPO H2   H  N N 353 
TPO HA   H  N N 354 
TPO HB   H  N N 355 
TPO HG21 H  N N 356 
TPO HG22 H  N N 357 
TPO HG23 H  N N 358 
TPO HOP2 H  N N 359 
TPO HOP3 H  N N 360 
TPO HXT  H  N N 361 
TRP N    N  N N 362 
TRP CA   C  N S 363 
TRP C    C  N N 364 
TRP O    O  N N 365 
TRP CB   C  N N 366 
TRP CG   C  Y N 367 
TRP CD1  C  Y N 368 
TRP CD2  C  Y N 369 
TRP NE1  N  Y N 370 
TRP CE2  C  Y N 371 
TRP CE3  C  Y N 372 
TRP CZ2  C  Y N 373 
TRP CZ3  C  Y N 374 
TRP CH2  C  Y N 375 
TRP OXT  O  N N 376 
TRP H    H  N N 377 
TRP H2   H  N N 378 
TRP HA   H  N N 379 
TRP HB2  H  N N 380 
TRP HB3  H  N N 381 
TRP HD1  H  N N 382 
TRP HE1  H  N N 383 
TRP HE3  H  N N 384 
TRP HZ2  H  N N 385 
TRP HZ3  H  N N 386 
TRP HH2  H  N N 387 
TRP HXT  H  N N 388 
TYR N    N  N N 389 
TYR CA   C  N S 390 
TYR C    C  N N 391 
TYR O    O  N N 392 
TYR CB   C  N N 393 
TYR CG   C  Y N 394 
TYR CD1  C  Y N 395 
TYR CD2  C  Y N 396 
TYR CE1  C  Y N 397 
TYR CE2  C  Y N 398 
TYR CZ   C  Y N 399 
TYR OH   O  N N 400 
TYR OXT  O  N N 401 
TYR H    H  N N 402 
TYR H2   H  N N 403 
TYR HA   H  N N 404 
TYR HB2  H  N N 405 
TYR HB3  H  N N 406 
TYR HD1  H  N N 407 
TYR HD2  H  N N 408 
TYR HE1  H  N N 409 
TYR HE2  H  N N 410 
TYR HH   H  N N 411 
TYR HXT  H  N N 412 
VAL N    N  N N 413 
VAL CA   C  N S 414 
VAL C    C  N N 415 
VAL O    O  N N 416 
VAL CB   C  N N 417 
VAL CG1  C  N N 418 
VAL CG2  C  N N 419 
VAL OXT  O  N N 420 
VAL H    H  N N 421 
VAL H2   H  N N 422 
VAL HA   H  N N 423 
VAL HB   H  N N 424 
VAL HG11 H  N N 425 
VAL HG12 H  N N 426 
VAL HG13 H  N N 427 
VAL HG21 H  N N 428 
VAL HG22 H  N N 429 
VAL HG23 H  N N 430 
VAL HXT  H  N N 431 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
IJX C1  C2   sing N N 152 
IJX C2  N1   sing N N 153 
IJX C2  O1   doub N N 154 
IJX N1  C3   sing N N 155 
IJX C3  C4   doub Y N 156 
IJX C3  C8   sing Y N 157 
IJX C4  C5   sing Y N 158 
IJX C8  C7   doub Y N 159 
IJX C5  C6   doub Y N 160 
IJX C7  C6   sing Y N 161 
IJX C6  BR1  sing N N 162 
IJX C4  H1   sing N N 163 
IJX C5  H2   sing N N 164 
IJX C7  H3   sing N N 165 
IJX C8  H4   sing N N 166 
IJX N1  H5   sing N N 167 
IJX C1  H6   sing N N 168 
IJX C1  H7   sing N N 169 
IJX C1  H8   sing N N 170 
ILE N   CA   sing N N 171 
ILE N   H    sing N N 172 
ILE N   H2   sing N N 173 
ILE CA  C    sing N N 174 
ILE CA  CB   sing N N 175 
ILE CA  HA   sing N N 176 
ILE C   O    doub N N 177 
ILE C   OXT  sing N N 178 
ILE CB  CG1  sing N N 179 
ILE CB  CG2  sing N N 180 
ILE CB  HB   sing N N 181 
ILE CG1 CD1  sing N N 182 
ILE CG1 HG12 sing N N 183 
ILE CG1 HG13 sing N N 184 
ILE CG2 HG21 sing N N 185 
ILE CG2 HG22 sing N N 186 
ILE CG2 HG23 sing N N 187 
ILE CD1 HD11 sing N N 188 
ILE CD1 HD12 sing N N 189 
ILE CD1 HD13 sing N N 190 
ILE OXT HXT  sing N N 191 
LEU N   CA   sing N N 192 
LEU N   H    sing N N 193 
LEU N   H2   sing N N 194 
LEU CA  C    sing N N 195 
LEU CA  CB   sing N N 196 
LEU CA  HA   sing N N 197 
LEU C   O    doub N N 198 
LEU C   OXT  sing N N 199 
LEU CB  CG   sing N N 200 
LEU CB  HB2  sing N N 201 
LEU CB  HB3  sing N N 202 
LEU CG  CD1  sing N N 203 
LEU CG  CD2  sing N N 204 
LEU CG  HG   sing N N 205 
LEU CD1 HD11 sing N N 206 
LEU CD1 HD12 sing N N 207 
LEU CD1 HD13 sing N N 208 
LEU CD2 HD21 sing N N 209 
LEU CD2 HD22 sing N N 210 
LEU CD2 HD23 sing N N 211 
LEU OXT HXT  sing N N 212 
LYS N   CA   sing N N 213 
LYS N   H    sing N N 214 
LYS N   H2   sing N N 215 
LYS CA  C    sing N N 216 
LYS CA  CB   sing N N 217 
LYS CA  HA   sing N N 218 
LYS C   O    doub N N 219 
LYS C   OXT  sing N N 220 
LYS CB  CG   sing N N 221 
LYS CB  HB2  sing N N 222 
LYS CB  HB3  sing N N 223 
LYS CG  CD   sing N N 224 
LYS CG  HG2  sing N N 225 
LYS CG  HG3  sing N N 226 
LYS CD  CE   sing N N 227 
LYS CD  HD2  sing N N 228 
LYS CD  HD3  sing N N 229 
LYS CE  NZ   sing N N 230 
LYS CE  HE2  sing N N 231 
LYS CE  HE3  sing N N 232 
LYS NZ  HZ1  sing N N 233 
LYS NZ  HZ2  sing N N 234 
LYS NZ  HZ3  sing N N 235 
LYS OXT HXT  sing N N 236 
MET N   CA   sing N N 237 
MET N   H    sing N N 238 
MET N   H2   sing N N 239 
MET CA  C    sing N N 240 
MET CA  CB   sing N N 241 
MET CA  HA   sing N N 242 
MET C   O    doub N N 243 
MET C   OXT  sing N N 244 
MET CB  CG   sing N N 245 
MET CB  HB2  sing N N 246 
MET CB  HB3  sing N N 247 
MET CG  SD   sing N N 248 
MET CG  HG2  sing N N 249 
MET CG  HG3  sing N N 250 
MET SD  CE   sing N N 251 
MET CE  HE1  sing N N 252 
MET CE  HE2  sing N N 253 
MET CE  HE3  sing N N 254 
MET OXT HXT  sing N N 255 
PHE N   CA   sing N N 256 
PHE N   H    sing N N 257 
PHE N   H2   sing N N 258 
PHE CA  C    sing N N 259 
PHE CA  CB   sing N N 260 
PHE CA  HA   sing N N 261 
PHE C   O    doub N N 262 
PHE C   OXT  sing N N 263 
PHE CB  CG   sing N N 264 
PHE CB  HB2  sing N N 265 
PHE CB  HB3  sing N N 266 
PHE CG  CD1  doub Y N 267 
PHE CG  CD2  sing Y N 268 
PHE CD1 CE1  sing Y N 269 
PHE CD1 HD1  sing N N 270 
PHE CD2 CE2  doub Y N 271 
PHE CD2 HD2  sing N N 272 
PHE CE1 CZ   doub Y N 273 
PHE CE1 HE1  sing N N 274 
PHE CE2 CZ   sing Y N 275 
PHE CE2 HE2  sing N N 276 
PHE CZ  HZ   sing N N 277 
PHE OXT HXT  sing N N 278 
PRO N   CA   sing N N 279 
PRO N   CD   sing N N 280 
PRO N   H    sing N N 281 
PRO CA  C    sing N N 282 
PRO CA  CB   sing N N 283 
PRO CA  HA   sing N N 284 
PRO C   O    doub N N 285 
PRO C   OXT  sing N N 286 
PRO CB  CG   sing N N 287 
PRO CB  HB2  sing N N 288 
PRO CB  HB3  sing N N 289 
PRO CG  CD   sing N N 290 
PRO CG  HG2  sing N N 291 
PRO CG  HG3  sing N N 292 
PRO CD  HD2  sing N N 293 
PRO CD  HD3  sing N N 294 
PRO OXT HXT  sing N N 295 
SER N   CA   sing N N 296 
SER N   H    sing N N 297 
SER N   H2   sing N N 298 
SER CA  C    sing N N 299 
SER CA  CB   sing N N 300 
SER CA  HA   sing N N 301 
SER C   O    doub N N 302 
SER C   OXT  sing N N 303 
SER CB  OG   sing N N 304 
SER CB  HB2  sing N N 305 
SER CB  HB3  sing N N 306 
SER OG  HG   sing N N 307 
SER OXT HXT  sing N N 308 
THR N   CA   sing N N 309 
THR N   H    sing N N 310 
THR N   H2   sing N N 311 
THR CA  C    sing N N 312 
THR CA  CB   sing N N 313 
THR CA  HA   sing N N 314 
THR C   O    doub N N 315 
THR C   OXT  sing N N 316 
THR CB  OG1  sing N N 317 
THR CB  CG2  sing N N 318 
THR CB  HB   sing N N 319 
THR OG1 HG1  sing N N 320 
THR CG2 HG21 sing N N 321 
THR CG2 HG22 sing N N 322 
THR CG2 HG23 sing N N 323 
THR OXT HXT  sing N N 324 
TPO N   CA   sing N N 325 
TPO N   H    sing N N 326 
TPO N   H2   sing N N 327 
TPO CA  CB   sing N N 328 
TPO CA  C    sing N N 329 
TPO CA  HA   sing N N 330 
TPO CB  CG2  sing N N 331 
TPO CB  OG1  sing N N 332 
TPO CB  HB   sing N N 333 
TPO CG2 HG21 sing N N 334 
TPO CG2 HG22 sing N N 335 
TPO CG2 HG23 sing N N 336 
TPO OG1 P    sing N N 337 
TPO P   O1P  doub N N 338 
TPO P   O2P  sing N N 339 
TPO P   O3P  sing N N 340 
TPO O2P HOP2 sing N N 341 
TPO O3P HOP3 sing N N 342 
TPO C   O    doub N N 343 
TPO C   OXT  sing N N 344 
TPO OXT HXT  sing N N 345 
TRP N   CA   sing N N 346 
TRP N   H    sing N N 347 
TRP N   H2   sing N N 348 
TRP CA  C    sing N N 349 
TRP CA  CB   sing N N 350 
TRP CA  HA   sing N N 351 
TRP C   O    doub N N 352 
TRP C   OXT  sing N N 353 
TRP CB  CG   sing N N 354 
TRP CB  HB2  sing N N 355 
TRP CB  HB3  sing N N 356 
TRP CG  CD1  doub Y N 357 
TRP CG  CD2  sing Y N 358 
TRP CD1 NE1  sing Y N 359 
TRP CD1 HD1  sing N N 360 
TRP CD2 CE2  doub Y N 361 
TRP CD2 CE3  sing Y N 362 
TRP NE1 CE2  sing Y N 363 
TRP NE1 HE1  sing N N 364 
TRP CE2 CZ2  sing Y N 365 
TRP CE3 CZ3  doub Y N 366 
TRP CE3 HE3  sing N N 367 
TRP CZ2 CH2  doub Y N 368 
TRP CZ2 HZ2  sing N N 369 
TRP CZ3 CH2  sing Y N 370 
TRP CZ3 HZ3  sing N N 371 
TRP CH2 HH2  sing N N 372 
TRP OXT HXT  sing N N 373 
TYR N   CA   sing N N 374 
TYR N   H    sing N N 375 
TYR N   H2   sing N N 376 
TYR CA  C    sing N N 377 
TYR CA  CB   sing N N 378 
TYR CA  HA   sing N N 379 
TYR C   O    doub N N 380 
TYR C   OXT  sing N N 381 
TYR CB  CG   sing N N 382 
TYR CB  HB2  sing N N 383 
TYR CB  HB3  sing N N 384 
TYR CG  CD1  doub Y N 385 
TYR CG  CD2  sing Y N 386 
TYR CD1 CE1  sing Y N 387 
TYR CD1 HD1  sing N N 388 
TYR CD2 CE2  doub Y N 389 
TYR CD2 HD2  sing N N 390 
TYR CE1 CZ   doub Y N 391 
TYR CE1 HE1  sing N N 392 
TYR CE2 CZ   sing Y N 393 
TYR CE2 HE2  sing N N 394 
TYR CZ  OH   sing N N 395 
TYR OH  HH   sing N N 396 
TYR OXT HXT  sing N N 397 
VAL N   CA   sing N N 398 
VAL N   H    sing N N 399 
VAL N   H2   sing N N 400 
VAL CA  C    sing N N 401 
VAL CA  CB   sing N N 402 
VAL CA  HA   sing N N 403 
VAL C   O    doub N N 404 
VAL C   OXT  sing N N 405 
VAL CB  CG1  sing N N 406 
VAL CB  CG2  sing N N 407 
VAL CB  HB   sing N N 408 
VAL CG1 HG11 sing N N 409 
VAL CG1 HG12 sing N N 410 
VAL CG1 HG13 sing N N 411 
VAL CG2 HG21 sing N N 412 
VAL CG2 HG22 sing N N 413 
VAL CG2 HG23 sing N N 414 
VAL OXT HXT  sing N N 415 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ET2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013543 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007520 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006809 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 -0.0527  
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P  15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLY A 1 1   ? -22.066 -7.225  24.092  1   64.3   ? -3  GLY A N   1 
ATOM   2    C  CA  . GLY A 1 1   ? -21.039 -6.94   25.109  1   66.07  ? -3  GLY A CA  1 
ATOM   3    C  C   . GLY A 1 1   ? -21.665 -6.961  26.502  1   76.7   ? -3  GLY A C   1 
ATOM   4    O  O   . GLY A 1 1   ? -21.665 -5.934  27.187  1   78.07  ? -3  GLY A O   1 
ATOM   5    N  N   . PRO A 1 2   ? -22.25  -8.104  26.958  1   78.01  ? -2  PRO A N   1 
ATOM   6    C  CA  . PRO A 1 2   ? -22.779 -8.208  28.325  1   71.78  ? -2  PRO A CA  1 
ATOM   7    C  C   . PRO A 1 2   ? -21.815 -8.286  29.516  1   64.59  ? -2  PRO A C   1 
ATOM   8    O  O   . PRO A 1 2   ? -22.265 -8.169  30.653  1   65.05  ? -2  PRO A O   1 
ATOM   9    C  CB  . PRO A 1 2   ? -23.668 -9.471  28.232  1   70.74  ? -2  PRO A CB  1 
ATOM   10   C  CG  . PRO A 1 2   ? -22.982 -10.339 27.209  1   66.31  ? -2  PRO A CG  1 
ATOM   11   C  CD  . PRO A 1 2   ? -22.492 -9.335  26.174  1   73.66  ? -2  PRO A CD  1 
ATOM   12   N  N   . GLY A 1 3   ? -20.51  -8.495  29.26   1   57.64  ? -1  GLY A N   1 
ATOM   13   C  CA  . GLY A 1 3   ? -19.538 -8.797  30.312  1   52.7   ? -1  GLY A CA  1 
ATOM   14   C  C   . GLY A 1 3   ? -18.512 -7.688  30.55   1   48.39  ? -1  GLY A C   1 
ATOM   15   O  O   . GLY A 1 3   ? -18.37  -6.794  29.72   1   43.89  ? -1  GLY A O   1 
ATOM   16   N  N   . SER A 1 4   ? -17.809 -7.798  31.69   1   54.03  ? 0   SER A N   1 
ATOM   17   C  CA  . SER A 1 4   ? -16.789 -6.909  32.246  1   50.59  ? 0   SER A CA  1 
ATOM   18   C  C   . SER A 1 4   ? -15.74  -7.799  32.914  1   45.17  ? 0   SER A C   1 
ATOM   19   O  O   . SER A 1 4   ? -16.042 -8.938  33.245  1   45.24  ? 0   SER A O   1 
ATOM   20   C  CB  . SER A 1 4   ? -17.385 -5.971  33.264  1   49.38  ? 0   SER A CB  1 
ATOM   21   O  OG  . SER A 1 4   ? -17.901 -6.718  34.362  1   55.39  ? 0   SER A OG  1 
ATOM   22   N  N   . MET A 1 5   ? -14.522 -7.306  33.138  1   41.55  ? 1   MET A N   1 
ATOM   23   C  CA  . MET A 1 5   ? -13.517 -8.194  33.699  1   36.75  ? 1   MET A CA  1 
ATOM   24   C  C   . MET A 1 5   ? -13.756 -8.487  35.177  1   37.54  ? 1   MET A C   1 
ATOM   25   O  O   . MET A 1 5   ? -13.179 -9.443  35.675  1   41.98  ? 1   MET A O   1 
ATOM   26   C  CB  . MET A 1 5   ? -12.094 -7.677  33.496  1   33.46  ? 1   MET A CB  1 
ATOM   27   C  CG  . MET A 1 5   ? -11.772 -7.452  32.057  1   35.16  ? 1   MET A CG  1 
ATOM   28   S  SD  . MET A 1 5   ? -12.286 -8.853  31.042  1   38.14  ? 1   MET A SD  1 
ATOM   29   C  CE  . MET A 1 5   ? -11.165 -10.038 31.8    1   39.32  ? 1   MET A CE  1 
ATOM   30   N  N   . GLU A 1 6   ? -14.587 -7.679  35.858  1   38.19  ? 2   GLU A N   1 
ATOM   31   C  CA  . GLU A 1 6   ? -14.898 -7.862  37.272  1   38.5   ? 2   GLU A CA  1 
ATOM   32   C  C   . GLU A 1 6   ? -15.447 -9.269  37.533  1   33.39  ? 2   GLU A C   1 
ATOM   33   O  O   . GLU A 1 6   ? -15.196 -9.835  38.599  1   32.37  ? 2   GLU A O   1 
ATOM   34   C  CB  . GLU A 1 6   ? -15.874 -6.806  37.802  1   47.89  ? 2   GLU A CB  1 
ATOM   35   C  CG  . GLU A 1 6   ? -16.236 -6.977  39.282  1   58.47  ? 2   GLU A CG  1 
ATOM   36   C  CD  . GLU A 1 6   ? -17.698 -6.867  39.75   1   69.13  ? 2   GLU A CD  1 
ATOM   37   O  OE1 . GLU A 1 6   ? -17.911 -6.645  40.972  1   74.54  ? 2   GLU A OE1 1 
ATOM   38   O  OE2 . GLU A 1 6   ? -18.646 -7.047  38.934  1   66.43  ? 2   GLU A OE2 1 
ATOM   39   N  N   . ASN A 1 7   ? -16.173 -9.832  36.552  1   29.22  ? 3   ASN A N   1 
ATOM   40   C  CA  . ASN A 1 7   ? -16.874 -11.1   36.723  1   26.9   ? 3   ASN A CA  1 
ATOM   41   C  C   . ASN A 1 7   ? -15.996 -12.3   36.397  1   24.85  ? 3   ASN A C   1 
ATOM   42   O  O   . ASN A 1 7   ? -16.457 -13.426 36.54   1   26.06  ? 3   ASN A O   1 
ATOM   43   C  CB  . ASN A 1 7   ? -18.127 -11.247 35.862  1   26.68  ? 3   ASN A CB  1 
ATOM   44   C  CG  . ASN A 1 7   ? -19.145 -10.172 36.155  1   32.23  ? 3   ASN A CG  1 
ATOM   45   O  OD1 . ASN A 1 7   ? -19.367 -9.819  37.332  1   32.28  ? 3   ASN A OD1 1 
ATOM   46   N  ND2 . ASN A 1 7   ? -19.747 -9.643  35.091  1   30.72  ? 3   ASN A ND2 1 
ATOM   47   N  N   . PHE A 1 8   ? -14.766 -12.078 35.927  1   22.39  ? 4   PHE A N   1 
ATOM   48   C  CA  . PHE A 1 8   ? -13.908 -13.208 35.626  1   21.05  ? 4   PHE A CA  1 
ATOM   49   C  C   . PHE A 1 8   ? -12.799 -13.35  36.66   1   21.84  ? 4   PHE A C   1 
ATOM   50   O  O   . PHE A 1 8   ? -12.327 -12.364 37.235  1   23.78  ? 4   PHE A O   1 
ATOM   51   C  CB  . PHE A 1 8   ? -13.332 -13.098 34.225  1   20.73  ? 4   PHE A CB  1 
ATOM   52   C  CG  . PHE A 1 8   ? -14.395 -13.247 33.159  1   21.09  ? 4   PHE A CG  1 
ATOM   53   C  CD1 . PHE A 1 8   ? -14.859 -14.51  32.809  1   20.94  ? 4   PHE A CD1 1 
ATOM   54   C  CD2 . PHE A 1 8   ? -14.902 -12.129 32.499  1   21.2   ? 4   PHE A CD2 1 
ATOM   55   C  CE1 . PHE A 1 8   ? -15.823 -14.66  31.82   1   22.91  ? 4   PHE A CE1 1 
ATOM   56   C  CE2 . PHE A 1 8   ? -15.869 -12.282 31.515  1   23.13  ? 4   PHE A CE2 1 
ATOM   57   C  CZ  . PHE A 1 8   ? -16.326 -13.546 31.166  1   22.49  ? 4   PHE A CZ  1 
ATOM   58   N  N   . GLN A 1 9   ? -12.432 -14.609 36.894  1   21.27  ? 5   GLN A N   1 
ATOM   59   C  CA  . GLN A 1 9   ? -11.321 -14.955 37.756  1   23.86  ? 5   GLN A CA  1 
ATOM   60   C  C   . GLN A 1 9   ? -10.308 -15.726 36.921  1   24     ? 5   GLN A C   1 
ATOM   61   O  O   . GLN A 1 9   ? -10.657 -16.753 36.36   1   27.3   ? 5   GLN A O   1 
ATOM   62   C  CB  . GLN A 1 9   ? -11.867 -15.826 38.885  1   26.95  ? 5   GLN A CB  1 
ATOM   63   C  CG  . GLN A 1 9   ? -10.811 -16.363 39.843  1   29.03  ? 5   GLN A CG  1 
ATOM   64   C  CD  . GLN A 1 9   ? -10.03  -15.245 40.483  1   32.96  ? 5   GLN A CD  1 
ATOM   65   O  OE1 . GLN A 1 9   ? -10.597 -14.33  41.101  1   37.11  ? 5   GLN A OE1 1 
ATOM   66   N  NE2 . GLN A 1 9   ? -8.718  -15.303 40.309  1   33.89  ? 5   GLN A NE2 1 
ATOM   67   N  N   . LYS A 1 10  ? -9.083  -15.207 36.791  1   24.16  ? 6   LYS A N   1 
ATOM   68   C  CA  . LYS A 1 10  ? -8.052  -15.897 36.032  1   24.95  ? 6   LYS A CA  1 
ATOM   69   C  C   . LYS A 1 10  ? -7.646  -17.147 36.801  1   22.65  ? 6   LYS A C   1 
ATOM   70   O  O   . LYS A 1 10  ? -7.645  -17.146 38.024  1   22.56  ? 6   LYS A O   1 
ATOM   71   C  CB  . LYS A 1 10  ? -6.894  -14.959 35.681  1   30.15  ? 6   LYS A CB  1 
ATOM   72   C  CG  . LYS A 1 10  ? -7.283  -13.953 34.6    1   40.21  ? 6   LYS A CG  1 
ATOM   73   C  CD  . LYS A 1 10  ? -6.155  -13.044 34.121  1   50.05  ? 6   LYS A CD  1 
ATOM   74   C  CE  . LYS A 1 10  ? -6.435  -12.455 32.759  1   49.33  ? 6   LYS A CE  1 
ATOM   75   N  NZ  . LYS A 1 10  ? -7.333  -11.311 32.89   1   51.63  ? 6   LYS A NZ  1 
ATOM   76   N  N   . VAL A 1 11  ? -7.382  -18.224 36.067  1   23.15  ? 7   VAL A N   1 
ATOM   77   C  CA  . VAL A 1 11  ? -7.071  -19.496 36.691  1   24.62  ? 7   VAL A CA  1 
ATOM   78   C  C   . VAL A 1 11  ? -5.623  -19.83  36.358  1   25.67  ? 7   VAL A C   1 
ATOM   79   O  O   . VAL A 1 11  ? -4.831  -20.061 37.264  1   28.32  ? 7   VAL A O   1 
ATOM   80   C  CB  . VAL A 1 11  ? -8.048  -20.63  36.31   1   24.91  ? 7   VAL A CB  1 
ATOM   81   C  CG1 . VAL A 1 11  ? -7.611  -21.976 36.868  1   25.02  ? 7   VAL A CG1 1 
ATOM   82   C  CG2 . VAL A 1 11  ? -9.472  -20.34  36.768  1   23.19  ? 7   VAL A CG2 1 
ATOM   83   N  N   . GLU A 1 12  ? -5.282  -19.801 35.066  1   25.79  ? 8   GLU A N   1 
ATOM   84   C  CA  . GLU A 1 12  ? -3.912  -20.039 34.657  1   26.36  ? 8   GLU A CA  1 
ATOM   85   C  C   . GLU A 1 12  ? -3.722  -19.621 33.204  1   27.33  ? 8   GLU A C   1 
ATOM   86   O  O   . GLU A 1 12  ? -4.699  -19.497 32.454  1   27.32  ? 8   GLU A O   1 
ATOM   87   C  CB  . GLU A 1 12  ? -3.578  -21.519 34.843  1   29.4   ? 8   GLU A CB  1 
ATOM   88   C  CG  . GLU A 1 12  ? -4.438  -22.442 33.985  1   33.8   ? 8   GLU A CG  1 
ATOM   89   C  CD  . GLU A 1 12  ? -4.236  -23.936 34.118  1   36.11  ? 8   GLU A CD  1 
ATOM   90   O  OE1 . GLU A 1 12  ? -4.428  -24.42  35.242  1   41.32  ? 8   GLU A OE1 1 
ATOM   91   O  OE2 . GLU A 1 12  ? -3.941  -24.616 33.115  1   37.92  ? 8   GLU A OE2 1 
ATOM   92   N  N   . LYS A 1 13  ? -2.447  -19.405 32.835  1   26.78  ? 9   LYS A N   1 
ATOM   93   C  CA  . LYS A 1 13  ? -2.051  -19.13  31.466  1   28     ? 9   LYS A CA  1 
ATOM   94   C  C   . LYS A 1 13  ? -2.208  -20.413 30.657  1   27.92  ? 9   LYS A C   1 
ATOM   95   O  O   . LYS A 1 13  ? -1.819  -21.473 31.124  1   31.38  ? 9   LYS A O   1 
ATOM   96   C  CB  . LYS A 1 13  ? -0.621  -18.586 31.419  1   28.8   ? 9   LYS A CB  1 
ATOM   97   C  CG  . LYS A 1 13  ? -0.077  -18.35  30.01   1   35.5   ? 9   LYS A CG  1 
ATOM   98   C  CD  . LYS A 1 13  ? 1.334   -17.771 29.957  1   42.02  ? 9   LYS A CD  1 
ATOM   99   C  CE  . LYS A 1 13  ? 1.69    -17.345 28.562  1   48.3   ? 9   LYS A CE  1 
ATOM   100  N  NZ  . LYS A 1 13  ? 2.942   -16.579 28.522  1   57.69  ? 9   LYS A NZ  1 
ATOM   101  N  N   . ILE A 1 14  ? -2.798  -20.325 29.463  1   25.33  ? 10  ILE A N   1 
ATOM   102  C  CA  . ILE A 1 14  ? -2.934  -21.529 28.666  1   27.21  ? 10  ILE A CA  1 
ATOM   103  C  C   . ILE A 1 14  ? -2.247  -21.386 27.318  1   29.39  ? 10  ILE A C   1 
ATOM   104  O  O   . ILE A 1 14  ? -2.113  -22.367 26.598  1   32.48  ? 10  ILE A O   1 
ATOM   105  C  CB  . ILE A 1 14  ? -4.392  -21.975 28.489  1   26.09  ? 10  ILE A CB  1 
ATOM   106  C  CG1 . ILE A 1 14  ? -5.266  -20.906 27.857  1   25.52  ? 10  ILE A CG1 1 
ATOM   107  C  CG2 . ILE A 1 14  ? -4.933  -22.464 29.824  1   28.36  ? 10  ILE A CG2 1 
ATOM   108  C  CD1 . ILE A 1 14  ? -6.71   -21.32  27.684  1   24.65  ? 10  ILE A CD1 1 
ATOM   109  N  N   . GLY A 1 15  ? -1.831  -20.171 26.983  1   31.29  ? 11  GLY A N   1 
ATOM   110  C  CA  . GLY A 1 15  ? -1.255  -19.964 25.672  1   37.14  ? 11  GLY A CA  1 
ATOM   111  C  C   . GLY A 1 15  ? -0.829  -18.519 25.468  1   44.36  ? 11  GLY A C   1 
ATOM   112  O  O   . GLY A 1 15  ? -1.121  -17.645 26.296  1   46.46  ? 11  GLY A O   1 
ATOM   113  N  N   . GLU A 1 16  ? -0.139  -18.314 24.343  1   49.93  ? 12  GLU A N   1 
ATOM   114  C  CA  . GLU A 1 16  ? 0.43    -17.031 23.996  1   58.18  ? 12  GLU A CA  1 
ATOM   115  C  C   . GLU A 1 16  ? 0.308   -16.878 22.485  1   63.89  ? 12  GLU A C   1 
ATOM   116  O  O   . GLU A 1 16  ? -0.207  -17.769 21.808  1   60.09  ? 12  GLU A O   1 
ATOM   117  C  CB  . GLU A 1 16  ? 1.852   -17.047 24.545  1   62.51  ? 12  GLU A CB  1 
ATOM   118  C  CG  . GLU A 1 16  ? 2.564   -15.722 24.319  1   80.12  ? 12  GLU A CG  1 
ATOM   119  C  CD  . GLU A 1 16  ? 3.954   -15.76  24.921  1   93.44  ? 12  GLU A CD  1 
ATOM   120  O  OE1 . GLU A 1 16  ? 4.34    -16.819 25.459  1   103.13 ? 12  GLU A OE1 1 
ATOM   121  O  OE2 . GLU A 1 16  ? 4.653   -14.725 24.87   1   100.55 ? 12  GLU A OE2 1 
ATOM   122  N  N   . GLY A 1 17  ? 0.76    -15.736 21.96   1   72.34  ? 13  GLY A N   1 
ATOM   123  C  CA  . GLY A 1 17  ? 0.528   -15.47  20.547  1   85.57  ? 13  GLY A CA  1 
ATOM   124  C  C   . GLY A 1 17  ? 1.152   -14.153 20.103  1   90.41  ? 13  GLY A C   1 
ATOM   125  O  O   . GLY A 1 17  ? 1.907   -13.542 20.856  1   95.87  ? 13  GLY A O   1 
ATOM   126  N  N   . THR A 1 18  ? 0.811   -13.724 18.878  1   89.98  ? 14  THR A N   1 
ATOM   127  C  CA  . THR A 1 18  ? 1.394   -12.531 18.283  1   88.02  ? 14  THR A CA  1 
ATOM   128  C  C   . THR A 1 18  ? 0.879   -11.282 18.989  1   88.54  ? 14  THR A C   1 
ATOM   129  O  O   . THR A 1 18  ? 1.614   -10.3   19.098  1   81.43  ? 14  THR A O   1 
ATOM   130  C  CB  . THR A 1 18  ? 1.098   -12.461 16.786  1   99.54  ? 14  THR A CB  1 
ATOM   131  O  OG1 . THR A 1 18  ? 1.852   -13.513 16.193  1   102.52 ? 14  THR A OG1 1 
ATOM   132  C  CG2 . THR A 1 18  ? 1.539   -11.141 16.182  1   99.89  ? 14  THR A CG2 1 
ATOM   133  N  N   . TYR A 1 19  ? -0.4    -11.309 19.401  1   90.96  ? 15  TYR A N   1 
ATOM   134  C  CA  . TYR A 1 19  ? -1.035  -10.12  19.956  1   90.47  ? 15  TYR A CA  1 
ATOM   135  C  C   . TYR A 1 19  ? -1.389  -10.298 21.433  1   80.64  ? 15  TYR A C   1 
ATOM   136  O  O   . TYR A 1 19  ? -1.852  -9.349  22.08   1   69.93  ? 15  TYR A O   1 
ATOM   137  C  CB  . TYR A 1 19  ? -2.137  -9.549  19.055  1   92.46  ? 15  TYR A CB  1 
ATOM   138  C  CG  . TYR A 1 19  ? -1.639  -8.752  17.852  1   94.98  ? 15  TYR A CG  1 
ATOM   139  C  CD1 . TYR A 1 19  ? -1.276  -7.409  17.977  1   97.23  ? 15  TYR A CD1 1 
ATOM   140  C  CD2 . TYR A 1 19  ? -1.539  -9.333  16.584  1   99.77  ? 15  TYR A CD2 1 
ATOM   141  C  CE1 . TYR A 1 19  ? -0.829  -6.676  16.883  1   99.74  ? 15  TYR A CE1 1 
ATOM   142  C  CE2 . TYR A 1 19  ? -1.091  -8.612  15.485  1   96.5   ? 15  TYR A CE2 1 
ATOM   143  C  CZ  . TYR A 1 19  ? -0.742  -7.278  15.633  1   98.01  ? 15  TYR A CZ  1 
ATOM   144  O  OH  . TYR A 1 19  ? -0.299  -6.594  14.532  1   90.12  ? 15  TYR A OH  1 
ATOM   145  N  N   . GLY A 1 20  ? -1.127  -11.488 21.989  1   68.13  ? 16  GLY A N   1 
ATOM   146  C  CA  . GLY A 1 20  ? -1.172  -11.533 23.441  1   55.86  ? 16  GLY A CA  1 
ATOM   147  C  C   . GLY A 1 20  ? -1.247  -12.923 24.06   1   50.1   ? 16  GLY A C   1 
ATOM   148  O  O   . GLY A 1 20  ? -0.922  -13.93  23.437  1   48.54  ? 16  GLY A O   1 
ATOM   149  N  N   . VAL A 1 21  ? -1.651  -12.934 25.333  1   47.81  ? 17  VAL A N   1 
ATOM   150  C  CA  . VAL A 1 21  ? -1.729  -14.141 26.137  1   47.73  ? 17  VAL A CA  1 
ATOM   151  C  C   . VAL A 1 21  ? -3.184  -14.596 26.236  1   44.89  ? 17  VAL A C   1 
ATOM   152  O  O   . VAL A 1 21  ? -4.097  -13.776 26.262  1   44.62  ? 17  VAL A O   1 
ATOM   153  C  CB  . VAL A 1 21  ? -1.129  -13.909 27.538  1   47.91  ? 17  VAL A CB  1 
ATOM   154  C  CG1 . VAL A 1 21  ? -1.715  -12.687 28.237  1   49.68  ? 17  VAL A CG1 1 
ATOM   155  C  CG2 . VAL A 1 21  ? -1.286  -15.135 28.429  1   48.81  ? 17  VAL A CG2 1 
ATOM   156  N  N   . VAL A 1 22  ? -3.377  -15.917 26.322  1   39.13  ? 18  VAL A N   1 
ATOM   157  C  CA  . VAL A 1 22  ? -4.671  -16.514 26.616  1   30.31  ? 18  VAL A CA  1 
ATOM   158  C  C   . VAL A 1 22  ? -4.661  -17.094 28.035  1   28.36  ? 18  VAL A C   1 
ATOM   159  O  O   . VAL A 1 22  ? -3.731  -17.783 28.45   1   28.03  ? 18  VAL A O   1 
ATOM   160  C  CB  . VAL A 1 22  ? -4.998  -17.599 25.58   1   27.66  ? 18  VAL A CB  1 
ATOM   161  C  CG1 . VAL A 1 22  ? -6.371  -18.188 25.836  1   27.38  ? 18  VAL A CG1 1 
ATOM   162  C  CG2 . VAL A 1 22  ? -4.87   -17.095 24.147  1   27.49  ? 18  VAL A CG2 1 
ATOM   163  N  N   . TYR A 1 23  ? -5.722  -16.824 28.791  1   26.87  ? 19  TYR A N   1 
ATOM   164  C  CA  . TYR A 1 23  ? -5.869  -17.416 30.105  1   25.42  ? 19  TYR A CA  1 
ATOM   165  C  C   . TYR A 1 23  ? -7.111  -18.301 30.159  1   24.38  ? 19  TYR A C   1 
ATOM   166  O  O   . TYR A 1 23  ? -8.095  -18.097 29.448  1   21.44  ? 19  TYR A O   1 
ATOM   167  C  CB  . TYR A 1 23  ? -6.076  -16.315 31.132  1   28.26  ? 19  TYR A CB  1 
ATOM   168  C  CG  . TYR A 1 23  ? -4.89   -15.399 31.396  1   37.12  ? 19  TYR A CG  1 
ATOM   169  C  CD1 . TYR A 1 23  ? -4.661  -14.292 30.59   1   38.3   ? 19  TYR A CD1 1 
ATOM   170  C  CD2 . TYR A 1 23  ? -4.052  -15.602 32.495  1   39.59  ? 19  TYR A CD2 1 
ATOM   171  C  CE1 . TYR A 1 23  ? -3.611  -13.431 30.857  1   44.55  ? 19  TYR A CE1 1 
ATOM   172  C  CE2 . TYR A 1 23  ? -2.996  -14.749 32.769  1   44.27  ? 19  TYR A CE2 1 
ATOM   173  C  CZ  . TYR A 1 23  ? -2.774  -13.662 31.939  1   50.72  ? 19  TYR A CZ  1 
ATOM   174  O  OH  . TYR A 1 23  ? -1.732  -12.813 32.204  1   60.55  ? 19  TYR A OH  1 
ATOM   175  N  N   . LYS A 1 24  ? -7.05   -19.319 31.017  1   22.93  ? 20  LYS A N   1 
ATOM   176  C  CA  . LYS A 1 24  ? -8.267  -19.981 31.43   1   20.77  ? 20  LYS A CA  1 
ATOM   177  C  C   . LYS A 1 24  ? -8.832  -19.189 32.599  1   20.37  ? 20  LYS A C   1 
ATOM   178  O  O   . LYS A 1 24  ? -8.139  -18.898 33.579  1   19.88  ? 20  LYS A O   1 
ATOM   179  C  CB  . LYS A 1 24  ? -7.989  -21.432 31.816  1   21.52  ? 20  LYS A CB  1 
ATOM   180  C  CG  . LYS A 1 24  ? -9.117  -22.157 32.513  1   20.74  ? 20  LYS A CG  1 
ATOM   181  C  CD  . LYS A 1 24  ? -8.691  -23.539 32.985  1   20.56  ? 20  LYS A CD  1 
ATOM   182  C  CE  . LYS A 1 24  ? -9.907  -24.292 33.432  1   21.8   ? 20  LYS A CE  1 
ATOM   183  N  NZ  . LYS A 1 24  ? -9.538  -25.617 33.933  1   22.95  ? 20  LYS A NZ  1 
ATOM   184  N  N   . ALA A 1 25  ? -10.101 -18.82  32.462  1   20.85  ? 21  ALA A N   1 
ATOM   185  C  CA  . ALA A 1 25  ? -10.764 -18.065 33.504  1   20.79  ? 21  ALA A CA  1 
ATOM   186  C  C   . ALA A 1 25  ? -12.125 -18.686 33.806  1   20.82  ? 21  ALA A C   1 
ATOM   187  O  O   . ALA A 1 25  ? -12.64  -19.546 33.077  1   19.67  ? 21  ALA A O   1 
ATOM   188  C  CB  . ALA A 1 25  ? -10.894 -16.638 33.05   1   20.68  ? 21  ALA A CB  1 
ATOM   189  N  N   . ARG A 1 26  ? -12.706 -18.198 34.89   1   19.01  ? 22  ARG A N   1 
ATOM   190  C  CA  . ARG A 1 26  ? -13.974 -18.7   35.357  1   20.66  ? 22  ARG A CA  1 
ATOM   191  C  C   . ARG A 1 26  ? -14.865 -17.486 35.578  1   19.24  ? 22  ARG A C   1 
ATOM   192  O  O   . ARG A 1 26  ? -14.431 -16.488 36.149  1   17.81  ? 22  ARG A O   1 
ATOM   193  C  CB  . ARG A 1 26  ? -13.734 -19.488 36.651  1   23.84  ? 22  ARG A CB  1 
ATOM   194  C  CG  . ARG A 1 26  ? -14.946 -20.177 37.258  1   28.16  ? 22  ARG A CG  1 
ATOM   195  C  CD  . ARG A 1 26  ? -14.581 -20.911 38.543  1   34.14  ? 22  ARG A CD  1 
ATOM   196  N  NE  . ARG A 1 26  ? -14.761 -20.016 39.7    1   39.44  ? 22  ARG A NE  1 
ATOM   197  C  CZ  . ARG A 1 26  ? -13.775 -19.424 40.381  1   39.92  ? 22  ARG A CZ  1 
ATOM   198  N  NH1 . ARG A 1 26  ? -12.513 -19.717 40.063  1   37.88  ? 22  ARG A NH1 1 
ATOM   199  N  NH2 . ARG A 1 26  ? -14.061 -18.537 41.337  1   35.33  ? 22  ARG A NH2 1 
ATOM   200  N  N   . ASN A 1 27  ? -16.097 -17.591 35.075  1   18.55  ? 23  ASN A N   1 
ATOM   201  C  CA  . ASN A 1 27  ? -17.158 -16.627 35.319  1   16.33  ? 23  ASN A CA  1 
ATOM   202  C  C   . ASN A 1 27  ? -17.656 -16.833 36.747  1   16.95  ? 23  ASN A C   1 
ATOM   203  O  O   . ASN A 1 27  ? -18.162 -17.898 37.096  1   17.67  ? 23  ASN A O   1 
ATOM   204  C  CB  . ASN A 1 27  ? -18.266 -16.808 34.285  1   15.12  ? 23  ASN A CB  1 
ATOM   205  C  CG  . ASN A 1 27  ? -19.36  -15.773 34.391  1   14.65  ? 23  ASN A CG  1 
ATOM   206  O  OD1 . ASN A 1 27  ? -19.757 -15.385 35.5    1   14.53  ? 23  ASN A OD1 1 
ATOM   207  N  ND2 . ASN A 1 27  ? -19.868 -15.329 33.25   1   13.17  ? 23  ASN A ND2 1 
ATOM   208  N  N   . LYS A 1 28  ? -17.529 -15.808 37.586  1   16.98  ? 24  LYS A N   1 
ATOM   209  C  CA  . LYS A 1 28  ? -17.735 -16.023 39      1   15.93  ? 24  LYS A CA  1 
ATOM   210  C  C   . LYS A 1 28  ? -19.223 -16.041 39.302  1   14.78  ? 24  LYS A C   1 
ATOM   211  O  O   . LYS A 1 28  ? -19.62  -16.37  40.417  1   14.72  ? 24  LYS A O   1 
ATOM   212  C  CB  . LYS A 1 28  ? -17.145 -14.853 39.781  1   19.42  ? 24  LYS A CB  1 
ATOM   213  C  CG  . LYS A 1 28  ? -15.65  -14.655 39.69   1   23.2   ? 24  LYS A CG  1 
ATOM   214  C  CD  . LYS A 1 28  ? -15.228 -13.611 40.734  1   28     ? 24  LYS A CD  1 
ATOM   215  C  CE  . LYS A 1 28  ? -14.06  -12.792 40.235  1   34.56  ? 24  LYS A CE  1 
ATOM   216  N  NZ  . LYS A 1 28  ? -13.692 -11.743 41.189  1   35.06  ? 24  LYS A NZ  1 
ATOM   217  N  N   . LEU A 1 29  ? -20.037 -15.644 38.324  1   14.24  ? 25  LEU A N   1 
ATOM   218  C  CA  . LEU A 1 29  ? -21.464 -15.508 38.568  1   14.38  ? 25  LEU A CA  1 
ATOM   219  C  C   . LEU A 1 29  ? -22.212 -16.736 38.054  1   15.1   ? 25  LEU A C   1 
ATOM   220  O  O   . LEU A 1 29  ? -23.147 -17.18  38.734  1   16.04  ? 25  LEU A O   1 
ATOM   221  C  CB  . LEU A 1 29  ? -21.99  -14.209 37.963  1   13.5   ? 25  LEU A CB  1 
ATOM   222  C  CG  . LEU A 1 29  ? -21.652 -12.944 38.754  1   12.69  ? 25  LEU A CG  1 
ATOM   223  C  CD1 . LEU A 1 29  ? -22.222 -11.721 38.07   1   13.04  ? 25  LEU A CD1 1 
ATOM   224  C  CD2 . LEU A 1 29  ? -22.207 -13.093 40.14   1   11.57  ? 25  LEU A CD2 1 
ATOM   225  N  N   . THR A 1 30  ? -21.784 -17.254 36.885  1   12.85  ? 26  THR A N   1 
ATOM   226  C  CA  . THR A 1 30  ? -22.436 -18.373 36.224  1   14.36  ? 26  THR A CA  1 
ATOM   227  C  C   . THR A 1 30  ? -21.715 -19.699 36.49   1   17.64  ? 26  THR A C   1 
ATOM   228  O  O   . THR A 1 30  ? -22.311 -20.771 36.317  1   18.75  ? 26  THR A O   1 
ATOM   229  C  CB  . THR A 1 30  ? -22.582 -18.192 34.705  1   12.17  ? 26  THR A CB  1 
ATOM   230  O  OG1 . THR A 1 30  ? -21.285 -18.136 34.133  1   11.21  ? 26  THR A OG1 1 
ATOM   231  C  CG2 . THR A 1 30  ? -23.373 -16.963 34.32   1   11.55  ? 26  THR A CG2 1 
ATOM   232  N  N   . GLY A 1 31  ? -20.403 -19.646 36.78   1   18.67  ? 27  GLY A N   1 
ATOM   233  C  CA  . GLY A 1 31  ? -19.586 -20.848 36.908  1   16.37  ? 27  GLY A CA  1 
ATOM   234  C  C   . GLY A 1 31  ? -18.889 -21.224 35.603  1   16.03  ? 27  GLY A C   1 
ATOM   235  O  O   . GLY A 1 31  ? -18.068 -22.145 35.571  1   17.19  ? 27  GLY A O   1 
ATOM   236  N  N   . GLU A 1 32  ? -19.204 -20.508 34.525  1   15.57  ? 28  GLU A N   1 
ATOM   237  C  CA  . GLU A 1 32  ? -18.744 -20.938 33.217  1   15.22  ? 28  GLU A CA  1 
ATOM   238  C  C   . GLU A 1 32  ? -17.234 -20.768 33.155  1   16.1   ? 28  GLU A C   1 
ATOM   239  O  O   . GLU A 1 32  ? -16.699 -19.756 33.609  1   16.82  ? 28  GLU A O   1 
ATOM   240  C  CB  . GLU A 1 32  ? -19.414 -20.131 32.107  1   14.62  ? 28  GLU A CB  1 
ATOM   241  C  CG  . GLU A 1 32  ? -19.147 -20.732 30.74   1   14.61  ? 28  GLU A CG  1 
ATOM   242  C  CD  . GLU A 1 32  ? -19.699 -19.898 29.611  1   16.63  ? 28  GLU A CD  1 
ATOM   243  O  OE1 . GLU A 1 32  ? -20.196 -18.775 29.82   1   15.85  ? 28  GLU A OE1 1 
ATOM   244  O  OE2 . GLU A 1 32  ? -19.598 -20.403 28.473  1   22.55  ? 28  GLU A OE2 1 
ATOM   245  N  N   . VAL A 1 33  ? -16.57  -21.765 32.565  1   16.01  ? 29  VAL A N   1 
ATOM   246  C  CA  . VAL A 1 33  ? -15.145 -21.705 32.318  1   15.89  ? 29  VAL A CA  1 
ATOM   247  C  C   . VAL A 1 33  ? -14.93  -21.225 30.894  1   17.3   ? 29  VAL A C   1 
ATOM   248  O  O   . VAL A 1 33  ? -15.556 -21.727 29.976  1   20.13  ? 29  VAL A O   1 
ATOM   249  C  CB  . VAL A 1 33  ? -14.494 -23.077 32.547  1   15.62  ? 29  VAL A CB  1 
ATOM   250  C  CG1 . VAL A 1 33  ? -13.001 -23.032 32.272  1   17.33  ? 29  VAL A CG1 1 
ATOM   251  C  CG2 . VAL A 1 33  ? -14.732 -23.588 33.954  1   14.99  ? 29  VAL A CG2 1 
ATOM   252  N  N   . VAL A 1 34  ? -13.999 -20.29  30.709  1   18.81  ? 30  VAL A N   1 
ATOM   253  C  CA  . VAL A 1 34  ? -13.816 -19.611 29.434  1   17.82  ? 30  VAL A CA  1 
ATOM   254  C  C   . VAL A 1 34  ? -12.322 -19.519 29.163  1   18.6   ? 30  VAL A C   1 
ATOM   255  O  O   . VAL A 1 34  ? -11.505 -19.747 30.047  1   18.7   ? 30  VAL A O   1 
ATOM   256  C  CB  . VAL A 1 34  ? -14.456 -18.201 29.465  1   17.57  ? 30  VAL A CB  1 
ATOM   257  C  CG1 . VAL A 1 34  ? -15.969 -18.252 29.695  1   15.79  ? 30  VAL A CG1 1 
ATOM   258  C  CG2 . VAL A 1 34  ? -13.775 -17.258 30.462  1   15.68  ? 30  VAL A CG2 1 
ATOM   259  N  N   . ALA A 1 35  ? -11.97  -19.185 27.926  1   20.5   ? 31  ALA A N   1 
ATOM   260  C  CA  . ALA A 1 35  ? -10.611 -18.79  27.607  1   19.73  ? 31  ALA A CA  1 
ATOM   261  C  C   . ALA A 1 35  ? -10.646 -17.311 27.239  1   20.82  ? 31  ALA A C   1 
ATOM   262  O  O   . ALA A 1 35  ? -11.382 -16.949 26.334  1   21.06  ? 31  ALA A O   1 
ATOM   263  C  CB  . ALA A 1 35  ? -10.128 -19.61  26.45   1   16.15  ? 31  ALA A CB  1 
ATOM   264  N  N   . LEU A 1 36  ? -9.885  -16.478 27.966  1   21.62  ? 32  LEU A N   1 
ATOM   265  C  CA  . LEU A 1 36  ? -9.743  -15.054 27.686  1   21.64  ? 32  LEU A CA  1 
ATOM   266  C  C   . LEU A 1 36  ? -8.504  -14.842 26.834  1   22.84  ? 32  LEU A C   1 
ATOM   267  O  O   . LEU A 1 36  ? -7.414  -15.135 27.299  1   24.68  ? 32  LEU A O   1 
ATOM   268  C  CB  . LEU A 1 36  ? -9.531  -14.335 29.01   1   20.16  ? 32  LEU A CB  1 
ATOM   269  C  CG  . LEU A 1 36  ? -10.72  -14.337 29.963  1   20.99  ? 32  LEU A CG  1 
ATOM   270  C  CD1 . LEU A 1 36  ? -10.313 -13.614 31.239  1   20.94  ? 32  LEU A CD1 1 
ATOM   271  C  CD2 . LEU A 1 36  ? -11.854 -13.606 29.261  1   21.18  ? 32  LEU A CD2 1 
ATOM   272  N  N   . LYS A 1 37  ? -8.669  -14.347 25.606  1   24.01  ? 33  LYS A N   1 
ATOM   273  C  CA  . LYS A 1 37  ? -7.54   -13.884 24.812  1   27.04  ? 33  LYS A CA  1 
ATOM   274  C  C   . LYS A 1 37  ? -7.455  -12.365 24.969  1   28.03  ? 33  LYS A C   1 
ATOM   275  O  O   . LYS A 1 37  ? -8.356  -11.661 24.538  1   31     ? 33  LYS A O   1 
ATOM   276  C  CB  . LYS A 1 37  ? -7.754  -14.327 23.356  1   28.7   ? 33  LYS A CB  1 
ATOM   277  C  CG  . LYS A 1 37  ? -6.714  -13.827 22.359  1   32.91  ? 33  LYS A CG  1 
ATOM   278  C  CD  . LYS A 1 37  ? -6.913  -14.14  20.879  1   34.24  ? 33  LYS A CD  1 
ATOM   279  C  CE  . LYS A 1 37  ? -7.356  -15.555 20.634  1   43.46  ? 33  LYS A CE  1 
ATOM   280  N  NZ  . LYS A 1 37  ? -6.94   -16.085 19.327  1   42.54  ? 33  LYS A NZ  1 
ATOM   281  N  N   . LYS A 1 38  ? -6.401  -11.856 25.614  1   30.18  ? 34  LYS A N   1 
ATOM   282  C  CA  . LYS A 1 38  ? -6.142  -10.423 25.693  1   32.82  ? 34  LYS A CA  1 
ATOM   283  C  C   . LYS A 1 38  ? -5.416  -9.948  24.434  1   37.45  ? 34  LYS A C   1 
ATOM   284  O  O   . LYS A 1 38  ? -4.403  -10.531 24.059  1   40.92  ? 34  LYS A O   1 
ATOM   285  C  CB  . LYS A 1 38  ? -5.265  -10.097 26.902  1   31.33  ? 34  LYS A CB  1 
ATOM   286  C  CG  . LYS A 1 38  ? -5.122  -8.616  27.16   1   38.47  ? 34  LYS A CG  1 
ATOM   287  C  CD  . LYS A 1 38  ? -4.547  -8.315  28.542  1   42.67  ? 34  LYS A CD  1 
ATOM   288  C  CE  . LYS A 1 38  ? -3.051  -8.209  28.536  1   46.61  ? 34  LYS A CE  1 
ATOM   289  N  NZ  . LYS A 1 38  ? -2.417  -9.061  29.552  1   46.32  ? 34  LYS A NZ  1 
ATOM   290  N  N   . ILE A 1 39  ? -5.969  -8.928  23.763  1   42.82  ? 35  ILE A N   1 
ATOM   291  C  CA  . ILE A 1 39  ? -5.299  -8.207  22.692  1   45.13  ? 35  ILE A CA  1 
ATOM   292  C  C   . ILE A 1 39  ? -4.95   -6.833  23.26   1   49.31  ? 35  ILE A C   1 
ATOM   293  O  O   . ILE A 1 39  ? -5.809  -6.151  23.823  1   47.22  ? 35  ILE A O   1 
ATOM   294  C  CB  . ILE A 1 39  ? -6.178  -8.138  21.422  1   44.89  ? 35  ILE A CB  1 
ATOM   295  C  CG1 . ILE A 1 39  ? -6.148  -9.438  20.59   1   46.16  ? 35  ILE A CG1 1 
ATOM   296  C  CG2 . ILE A 1 39  ? -5.791  -6.95   20.548  1   47.43  ? 35  ILE A CG2 1 
ATOM   297  C  CD1 . ILE A 1 39  ? -7.2    -10.461 20.975  1   44.81  ? 35  ILE A CD1 1 
ATOM   298  N  N   . ARG A 1 40  ? -3.667  -6.456  23.187  1   61.35  ? 36  ARG A N   1 
ATOM   299  C  CA  . ARG A 1 40  ? -3.233  -5.163  23.705  1   64.41  ? 36  ARG A CA  1 
ATOM   300  C  C   . ARG A 1 40  ? -3.364  -4.096  22.619  1   64.05  ? 36  ARG A C   1 
ATOM   301  O  O   . ARG A 1 40  ? -2.926  -4.31   21.483  1   61.05  ? 36  ARG A O   1 
ATOM   302  C  CB  . ARG A 1 40  ? -1.807  -5.251  24.257  1   69.73  ? 36  ARG A CB  1 
ATOM   303  C  CG  . ARG A 1 40  ? -1.703  -5.126  25.769  1   79.07  ? 36  ARG A CG  1 
ATOM   304  C  CD  . ARG A 1 40  ? -0.253  -5.163  26.224  1   87.34  ? 36  ARG A CD  1 
ATOM   305  N  NE  . ARG A 1 40  ? 0.098   -6.531  26.622  1   91.51  ? 36  ARG A NE  1 
ATOM   306  C  CZ  . ARG A 1 40  ? -0.062  -7.026  27.844  1   90.79  ? 36  ARG A CZ  1 
ATOM   307  N  NH1 . ARG A 1 40  ? 0.154   -8.314  28.064  1   92.59  ? 36  ARG A NH1 1 
ATOM   308  N  NH2 . ARG A 1 40  ? -0.452  -6.23   28.828  1   80.24  ? 36  ARG A NH2 1 
ATOM   309  N  N   . LEU A 1 41  ? -3.957  -2.961  22.977  1   58.42  ? 37  LEU A N   1 
ATOM   310  C  CA  . LEU A 1 41  ? -4.16   -1.887  21.979  1   59.05  ? 37  LEU A CA  1 
ATOM   311  C  C   . LEU A 1 41  ? -3.209  -0.735  22.318  1   79.05  ? 37  LEU A C   1 
ATOM   312  O  O   . LEU A 1 41  ? -2.79   -0.019  21.387  1   89.28  ? 37  LEU A O   1 
ATOM   313  C  CB  . LEU A 1 41  ? -5.629  -1.479  21.996  1   45.92  ? 37  LEU A CB  1 
ATOM   314  C  CG  . LEU A 1 41  ? -6.64   -2.603  21.761  1   41.2   ? 37  LEU A CG  1 
ATOM   315  C  CD1 . LEU A 1 41  ? -8.051  -2.089  21.97   1   37.4   ? 37  LEU A CD1 1 
ATOM   316  C  CD2 . LEU A 1 41  ? -6.479  -3.158  20.359  1   37.02  ? 37  LEU A CD2 1 
ATOM   317  N  N   . ASP A 1 42  ? -2.862  -0.647  23.652  1   97.27  ? 38  ASP A N   1 
ATOM   318  C  CA  . ASP A 1 42  ? -1.89   0.387   24.102  1   101.34 ? 38  ASP A CA  1 
ATOM   319  C  C   . ASP A 1 42  ? -0.654  0.337   23.21   1   104.92 ? 38  ASP A C   1 
ATOM   320  O  O   . ASP A 1 42  ? -0.313  1.366   22.591  1   98.28  ? 38  ASP A O   1 
ATOM   321  C  CB  . ASP A 1 42  ? -1.464  0.167   25.541  1   94.83  ? 38  ASP A CB  1 
ATOM   322  C  CG  . ASP A 1 42  ? -1.468  -1.284  25.995  1   99.71  ? 38  ASP A CG  1 
ATOM   323  O  OD1 . ASP A 1 42  ? -1.096  -2.14   25.176  1   87.28  ? 38  ASP A OD1 1 
ATOM   324  O  OD2 . ASP A 1 42  ? -1.841  -1.54   27.157  1   115.52 ? 38  ASP A OD2 1 
ATOM   325  N  N   . THR A 1 43  ? -0.033  -0.791  23.118  1   104.53 ? 39  THR A N   1 
ATOM   326  C  CA  . THR A 1 43  ? 1.209   -0.978  22.358  1   107.28 ? 39  THR A CA  1 
ATOM   327  C  C   . THR A 1 43  ? 0.978   -0.684  20.901  1   117.35 ? 39  THR A C   1 
ATOM   328  O  O   . THR A 1 43  ? 1.932   -0.221  20.248  1   139.52 ? 39  THR A O   1 
ATOM   329  C  CB  . THR A 1 43  ? 1.624   -2.431  22.556  1   106.79 ? 39  THR A CB  1 
ATOM   330  O  OG1 . THR A 1 43  ? 2.599   -2.692  21.552  1   111.64 ? 39  THR A OG1 1 
ATOM   331  C  CG2 . THR A 1 43  ? 0.465   -3.394  22.385  1   97.75  ? 39  THR A CG2 1 
ATOM   332  N  N   . GLU A 1 44  ? -0.236  -0.907  20.395  1   106.27 ? 40  GLU A N   1 
ATOM   333  C  CA  . GLU A 1 44  ? -0.461  -0.783  18.93   1   88.9   ? 40  GLU A CA  1 
ATOM   334  C  C   . GLU A 1 44  ? -0.419  0.677   18.459  1   73.27  ? 40  GLU A C   1 
ATOM   335  O  O   . GLU A 1 44  ? -1.26   1.474   18.919  1   65.15  ? 40  GLU A O   1 
ATOM   336  C  CB  . GLU A 1 44  ? -1.767  -1.474  18.539  1   91.16  ? 40  GLU A CB  1 
ATOM   337  C  CG  . GLU A 1 44  ? -2.023  -1.447  17.035  1   107.47 ? 40  GLU A CG  1 
ATOM   338  C  CD  . GLU A 1 44  ? -1.021  -2.229  16.204  1   104.51 ? 40  GLU A CD  1 
ATOM   339  O  OE1 . GLU A 1 44  ? -0.248  -3.012  16.795  1   95.89  ? 40  GLU A OE1 1 
ATOM   340  O  OE2 . GLU A 1 44  ? -1.004  -2.055  14.968  1   107    ? 40  GLU A OE2 1 
ATOM   341  N  N   . THR A 1 45  ? 0.515   0.994   17.557  1   65.37  ? 41  THR A N   1 
ATOM   342  C  CA  . THR A 1 45  ? 0.525   2.357   16.98   1   61.56  ? 41  THR A CA  1 
ATOM   343  C  C   . THR A 1 45  ? -0.271  2.328   15.699  1   51.89  ? 41  THR A C   1 
ATOM   344  O  O   . THR A 1 45  ? -0.199  3.303   14.942  1   49.84  ? 41  THR A O   1 
ATOM   345  C  CB  . THR A 1 45  ? 1.969   2.792   16.742  1   62.12  ? 41  THR A CB  1 
ATOM   346  O  OG1 . THR A 1 45  ? 2.339   2.189   15.506  1   65.51  ? 41  THR A OG1 1 
ATOM   347  C  CG2 . THR A 1 45  ? 2.902   2.327   17.845  1   58.31  ? 41  THR A CG2 1 
ATOM   348  N  N   . GLU A 1 46  ? -0.985  1.235   15.444  1   41.48  ? 42  GLU A N   1 
ATOM   349  C  CA  . GLU A 1 46  ? -1.799  1.078   14.252  1   35.89  ? 42  GLU A CA  1 
ATOM   350  C  C   . GLU A 1 46  ? -3.244  0.744   14.608  1   29.9   ? 42  GLU A C   1 
ATOM   351  O  O   . GLU A 1 46  ? -3.944  0.16    13.777  1   27.47  ? 42  GLU A O   1 
ATOM   352  C  CB  . GLU A 1 46  ? -1.194  0.108   13.234  1   37.96  ? 42  GLU A CB  1 
ATOM   353  C  CG  . GLU A 1 46  ? 0.068   0.647   12.558  1   44.5   ? 42  GLU A CG  1 
ATOM   354  C  CD  . GLU A 1 46  ? 0.012   1.92    11.709  1   43.71  ? 42  GLU A CD  1 
ATOM   355  O  OE1 . GLU A 1 46  ? -0.418  1.849   10.525  1   41.65  ? 42  GLU A OE1 1 
ATOM   356  O  OE2 . GLU A 1 46  ? 0.415   2.99    12.238  1   41.72  ? 42  GLU A OE2 1 
ATOM   357  N  N   . GLY A 1 47  ? -3.688  1.164   15.807  1   25.1   ? 43  GLY A N   1 
ATOM   358  C  CA  . GLY A 1 47  ? -5.038  0.894   16.289  1   21.6   ? 43  GLY A CA  1 
ATOM   359  C  C   . GLY A 1 47  ? -5.35   -0.606  16.296  1   21.14  ? 43  GLY A C   1 
ATOM   360  O  O   . GLY A 1 47  ? -4.447  -1.434  16.38   1   21.64  ? 43  GLY A O   1 
ATOM   361  N  N   . VAL A 1 48  ? -6.632  -0.97   16.192  1   18.69  ? 44  VAL A N   1 
ATOM   362  C  CA  . VAL A 1 48  ? -6.982  -2.372  16.334  1   16.47  ? 44  VAL A CA  1 
ATOM   363  C  C   . VAL A 1 48  ? -6.379  -3.186  15.191  1   16.99  ? 44  VAL A C   1 
ATOM   364  O  O   . VAL A 1 48  ? -6.52   -2.857  14.025  1   16.32  ? 44  VAL A O   1 
ATOM   365  C  CB  . VAL A 1 48  ? -8.498  -2.557  16.454  1   14.6   ? 44  VAL A CB  1 
ATOM   366  C  CG1 . VAL A 1 48  ? -8.867  -4.013  16.589  1   13.8   ? 44  VAL A CG1 1 
ATOM   367  C  CG2 . VAL A 1 48  ? -9.044  -1.772  17.627  1   14.31  ? 44  VAL A CG2 1 
ATOM   368  N  N   . PRO A 1 49  ? -5.677  -4.291  15.492  1   18.71  ? 45  PRO A N   1 
ATOM   369  C  CA  . PRO A 1 49  ? -5.012  -5.092  14.469  1   19.97  ? 45  PRO A CA  1 
ATOM   370  C  C   . PRO A 1 49  ? -5.984  -5.75   13.498  1   22.5   ? 45  PRO A C   1 
ATOM   371  O  O   . PRO A 1 49  ? -7.042  -6.242  13.897  1   24.14  ? 45  PRO A O   1 
ATOM   372  C  CB  . PRO A 1 49  ? -4.276  -6.175  15.27   1   19.29  ? 45  PRO A CB  1 
ATOM   373  C  CG  . PRO A 1 49  ? -4.23   -5.621  16.656  1   20.44  ? 45  PRO A CG  1 
ATOM   374  C  CD  . PRO A 1 49  ? -5.504  -4.841  16.84   1   20.66  ? 45  PRO A CD  1 
ATOM   375  N  N   . SER A 1 50  ? -5.584  -5.835  12.232  1   22.8   ? 46  SER A N   1 
ATOM   376  C  CA  . SER A 1 50  ? -6.429  -6.468  11.234  1   22.71  ? 46  SER A CA  1 
ATOM   377  C  C   . SER A 1 50  ? -6.751  -7.913  11.625  1   23.31  ? 46  SER A C   1 
ATOM   378  O  O   . SER A 1 50  ? -7.9    -8.328  11.495  1   25.47  ? 46  SER A O   1 
ATOM   379  C  CB  . SER A 1 50  ? -5.845  -6.329  9.848   1   22.42  ? 46  SER A CB  1 
ATOM   380  O  OG  . SER A 1 50  ? -4.545  -6.901  9.769   1   27.94  ? 46  SER A OG  1 
ATOM   381  N  N   . THR A 1 51  ? -5.757  -8.682  12.104  1   23.25  ? 47  THR A N   1 
ATOM   382  C  CA  . THR A 1 51  ? -6.017  -10.039 12.592  1   22.77  ? 47  THR A CA  1 
ATOM   383  C  C   . THR A 1 51  ? -7.225  -10.035 13.526  1   20.67  ? 47  THR A C   1 
ATOM   384  O  O   . THR A 1 51  ? -8.129  -10.816 13.318  1   20.49  ? 47  THR A O   1 
ATOM   385  C  CB  . THR A 1 51  ? -4.812  -10.745 13.234  1   24.65  ? 47  THR A CB  1 
ATOM   386  O  OG1 . THR A 1 51  ? -4.049  -9.815  14.006  1   27.66  ? 47  THR A OG1 1 
ATOM   387  C  CG2 . THR A 1 51  ? -3.852  -11.345 12.223  1   24.08  ? 47  THR A CG2 1 
ATOM   388  N  N   . ALA A 1 52  ? -7.262  -9.148  14.529  1   20.14  ? 48  ALA A N   1 
ATOM   389  C  CA  . ALA A 1 52  ? -8.33   -9.187  15.52   1   21.09  ? 48  ALA A CA  1 
ATOM   390  C  C   . ALA A 1 52  ? -9.701  -8.822  14.925  1   20.86  ? 48  ALA A C   1 
ATOM   391  O  O   . ALA A 1 52  ? -10.697 -9.452  15.267  1   21.18  ? 48  ALA A O   1 
ATOM   392  C  CB  . ALA A 1 52  ? -7.99   -8.346  16.746  1   19.85  ? 48  ALA A CB  1 
ATOM   393  N  N   . ILE A 1 53  ? -9.75   -7.798  14.064  1   18.37  ? 49  ILE A N   1 
ATOM   394  C  CA  . ILE A 1 53  ? -10.931 -7.384  13.32   1   17.09  ? 49  ILE A CA  1 
ATOM   395  C  C   . ILE A 1 53  ? -11.562 -8.542  12.535  1   19.26  ? 49  ILE A C   1 
ATOM   396  O  O   . ILE A 1 53  ? -12.779 -8.717  12.541  1   20.76  ? 49  ILE A O   1 
ATOM   397  C  CB  . ILE A 1 53  ? -10.545 -6.202  12.422  1   15.98  ? 49  ILE A CB  1 
ATOM   398  C  CG1 . ILE A 1 53  ? -10.522 -4.937  13.265  1   14.7   ? 49  ILE A CG1 1 
ATOM   399  C  CG2 . ILE A 1 53  ? -11.49  -6.072  11.235  1   15.58  ? 49  ILE A CG2 1 
ATOM   400  C  CD1 . ILE A 1 53  ? -9.947  -3.738  12.568  1   13.64  ? 49  ILE A CD1 1 
ATOM   401  N  N   . ARG A 1 54  ? -10.761 -9.345  11.84   1   19.13  ? 50  ARG A N   1 
ATOM   402  C  CA  . ARG A 1 54  ? -11.329 -10.477 11.13   1   19.79  ? 50  ARG A CA  1 
ATOM   403  C  C   . ARG A 1 54  ? -11.767 -11.549 12.121  1   22.34  ? 50  ARG A C   1 
ATOM   404  O  O   . ARG A 1 54  ? -12.827 -12.147 11.97   1   24.19  ? 50  ARG A O   1 
ATOM   405  C  CB  . ARG A 1 54  ? -10.291 -11.034 10.152  1   19.7   ? 50  ARG A CB  1 
ATOM   406  C  CG  . ARG A 1 54  ? -9.986  -10.032 9.041   1   21.71  ? 50  ARG A CG  1 
ATOM   407  C  CD  . ARG A 1 54  ? -8.889  -10.556 8.135   1   20.07  ? 50  ARG A CD  1 
ATOM   408  N  NE  . ARG A 1 54  ? -8.739  -9.79   6.907   1   18.85  ? 50  ARG A NE  1 
ATOM   409  C  CZ  . ARG A 1 54  ? -7.724  -9.961  6.068   1   19.44  ? 50  ARG A CZ  1 
ATOM   410  N  NH1 . ARG A 1 54  ? -6.811  -10.905 6.278   1   17.74  ? 50  ARG A NH1 1 
ATOM   411  N  NH2 . ARG A 1 54  ? -7.616  -9.132  5.045   1   17.64  ? 50  ARG A NH2 1 
ATOM   412  N  N   . GLU A 1 55  ? -10.923 -11.853 13.107  1   24.96  ? 51  GLU A N   1 
ATOM   413  C  CA  . GLU A 1 55  ? -11.25  -12.943 14.011  1   26.19  ? 51  GLU A CA  1 
ATOM   414  C  C   . GLU A 1 55  ? -12.612 -12.644 14.636  1   25.51  ? 51  GLU A C   1 
ATOM   415  O  O   . GLU A 1 55  ? -13.53  -13.455 14.548  1   27.07  ? 51  GLU A O   1 
ATOM   416  C  CB  . GLU A 1 55  ? -10.135 -13.125 15.037  1   28.02  ? 51  GLU A CB  1 
ATOM   417  C  CG  . GLU A 1 55  ? -10.466 -14.23  16.026  1   32.76  ? 51  GLU A CG  1 
ATOM   418  C  CD  . GLU A 1 55  ? -9.323  -14.837 16.822  1   36.83  ? 51  GLU A CD  1 
ATOM   419  O  OE1 . GLU A 1 55  ? -8.491  -14.09  17.366  1   34.08  ? 51  GLU A OE1 1 
ATOM   420  O  OE2 . GLU A 1 55  ? -9.319  -16.093 16.93   1   48.06  ? 51  GLU A OE2 1 
ATOM   421  N  N   . ILE A 1 56  ? -12.758 -11.431 15.177  1   19.97  ? 52  ILE A N   1 
ATOM   422  C  CA  . ILE A 1 56  ? -13.969 -11.09  15.877  1   19.99  ? 52  ILE A CA  1 
ATOM   423  C  C   . ILE A 1 56  ? -15.135 -11.076 14.892  1   22.79  ? 52  ILE A C   1 
ATOM   424  O  O   . ILE A 1 56  ? -16.141 -11.744 15.127  1   24.66  ? 52  ILE A O   1 
ATOM   425  C  CB  . ILE A 1 56  ? -13.849 -9.758  16.636  1   19.88  ? 52  ILE A CB  1 
ATOM   426  C  CG1 . ILE A 1 56  ? -12.631 -9.761  17.59   1   20.33  ? 52  ILE A CG1 1 
ATOM   427  C  CG2 . ILE A 1 56  ? -15.164 -9.473  17.371  1   18.38  ? 52  ILE A CG2 1 
ATOM   428  C  CD1 . ILE A 1 56  ? -12.337 -8.434  18.282  1   20     ? 52  ILE A CD1 1 
ATOM   429  N  N   . SER A 1 57  ? -15.011 -10.315 13.795  1   22.16  ? 53  SER A N   1 
ATOM   430  C  CA  . SER A 1 57  ? -16.15  -10.186 12.897  1   23.89  ? 53  SER A CA  1 
ATOM   431  C  C   . SER A 1 57  ? -16.565 -11.543 12.32   1   24.84  ? 53  SER A C   1 
ATOM   432  O  O   . SER A 1 57  ? -17.752 -11.831 12.173  1   28.53  ? 53  SER A O   1 
ATOM   433  C  CB  . SER A 1 57  ? -15.955 -9.141  11.82   1   23.59  ? 53  SER A CB  1 
ATOM   434  O  OG  . SER A 1 57  ? -14.87  -9.49   10.974  1   26.46  ? 53  SER A OG  1 
ATOM   435  N  N   . LEU A 1 58  ? -15.605 -12.391 11.979  1   21.85  ? 54  LEU A N   1 
ATOM   436  C  CA  . LEU A 1 58  ? -16.02  -13.592 11.28   1   23.95  ? 54  LEU A CA  1 
ATOM   437  C  C   . LEU A 1 58  ? -16.582 -14.58  12.292  1   27.92  ? 54  LEU A C   1 
ATOM   438  O  O   . LEU A 1 58  ? -17.508 -15.323 11.974  1   30.5   ? 54  LEU A O   1 
ATOM   439  C  CB  . LEU A 1 58  ? -14.915 -14.218 10.44   1   20.58  ? 54  LEU A CB  1 
ATOM   440  C  CG  . LEU A 1 58  ? -14.305 -13.304 9.385   1   19.24  ? 54  LEU A CG  1 
ATOM   441  C  CD1 . LEU A 1 58  ? -13.089 -13.985 8.753   1   18.31  ? 54  LEU A CD1 1 
ATOM   442  C  CD2 . LEU A 1 58  ? -15.442 -13.011 8.427   1   17.33  ? 54  LEU A CD2 1 
ATOM   443  N  N   . LEU A 1 59  ? -16.051 -14.553 13.516  1   28.29  ? 55  LEU A N   1 
ATOM   444  C  CA  . LEU A 1 59  ? -16.505 -15.51  14.51   1   30.39  ? 55  LEU A CA  1 
ATOM   445  C  C   . LEU A 1 59  ? -17.902 -15.183 15.041  1   32.42  ? 55  LEU A C   1 
ATOM   446  O  O   . LEU A 1 59  ? -18.614 -16.093 15.439  1   36.36  ? 55  LEU A O   1 
ATOM   447  C  CB  . LEU A 1 59  ? -15.497 -15.641 15.641  1   28.29  ? 55  LEU A CB  1 
ATOM   448  C  CG  . LEU A 1 59  ? -14.371 -16.643 15.414  1   25.93  ? 55  LEU A CG  1 
ATOM   449  C  CD1 . LEU A 1 59  ? -13.441 -16.587 16.602  1   26.33  ? 55  LEU A CD1 1 
ATOM   450  C  CD2 . LEU A 1 59  ? -14.935 -18.029 15.225  1   25.23  ? 55  LEU A CD2 1 
ATOM   451  N  N   . LYS A 1 60  ? -18.296 -13.904 15.063  1   32.91  ? 56  LYS A N   1 
ATOM   452  C  CA  . LYS A 1 60  ? -19.649 -13.529 15.452  1   36.58  ? 56  LYS A CA  1 
ATOM   453  C  C   . LYS A 1 60  ? -20.683 -14.322 14.651  1   39.84  ? 56  LYS A C   1 
ATOM   454  O  O   . LYS A 1 60  ? -21.646 -14.84  15.202  1   49.79  ? 56  LYS A O   1 
ATOM   455  C  CB  . LYS A 1 60  ? -19.891 -12.028 15.256  1   35.34  ? 56  LYS A CB  1 
ATOM   456  C  CG  . LYS A 1 60  ? -19.107 -11.164 16.215  1   35.4   ? 56  LYS A CG  1 
ATOM   457  C  CD  . LYS A 1 60  ? -19.789 -9.832  16.456  1   40.82  ? 56  LYS A CD  1 
ATOM   458  C  CE  . LYS A 1 60  ? -20.763 -9.885  17.576  1   45.2   ? 56  LYS A CE  1 
ATOM   459  N  NZ  . LYS A 1 60  ? -21.647 -8.713  17.588  1   49.04  ? 56  LYS A NZ  1 
ATOM   460  N  N   . GLU A 1 61  ? -20.432 -14.46  13.351  1   40.73  ? 57  GLU A N   1 
ATOM   461  C  CA  . GLU A 1 61  ? -21.334 -15.071 12.386  1   43.37  ? 57  GLU A CA  1 
ATOM   462  C  C   . GLU A 1 61  ? -21.353 -16.607 12.425  1   40.52  ? 57  GLU A C   1 
ATOM   463  O  O   . GLU A 1 61  ? -22.332 -17.231 11.993  1   46.9   ? 57  GLU A O   1 
ATOM   464  C  CB  . GLU A 1 61  ? -20.832 -14.58  11.028  1   48.73  ? 57  GLU A CB  1 
ATOM   465  C  CG  . GLU A 1 61  ? -20.978 -13.069 10.863  1   54.32  ? 57  GLU A CG  1 
ATOM   466  C  CD  . GLU A 1 61  ? -20.925 -12.655 9.407   1   64.91  ? 57  GLU A CD  1 
ATOM   467  O  OE1 . GLU A 1 61  ? -20.408 -13.459 8.603   1   72.61  ? 57  GLU A OE1 1 
ATOM   468  O  OE2 . GLU A 1 61  ? -21.447 -11.569 9.069   1   84.7   ? 57  GLU A OE2 1 
ATOM   469  N  N   . LEU A 1 62  ? -20.264 -17.221 12.899  1   32.97  ? 58  LEU A N   1 
ATOM   470  C  CA  . LEU A 1 62  ? -20.073 -18.655 12.806  1   29.31  ? 58  LEU A CA  1 
ATOM   471  C  C   . LEU A 1 62  ? -20.482 -19.35  14.1    1   28.77  ? 58  LEU A C   1 
ATOM   472  O  O   . LEU A 1 62  ? -19.64  -19.695 14.918  1   33.43  ? 58  LEU A O   1 
ATOM   473  C  CB  . LEU A 1 62  ? -18.605 -18.927 12.482  1   27.89  ? 58  LEU A CB  1 
ATOM   474  C  CG  . LEU A 1 62  ? -18.106 -18.384 11.14   1   31.18  ? 58  LEU A CG  1 
ATOM   475  C  CD1 . LEU A 1 62  ? -16.612 -18.579 11.15   1   33.99  ? 58  LEU A CD1 1 
ATOM   476  C  CD2 . LEU A 1 62  ? -18.748 -19.02  9.903   1   29.02  ? 58  LEU A CD2 1 
ATOM   477  N  N   A ASN A 1 63  ? -21.779 -19.601 14.242  0.5 28.02  ? 59  ASN A N   1 
ATOM   478  N  N   B ASN A 1 63  ? -21.786 -19.54  14.304  0.5 28.33  ? 59  ASN A N   1 
ATOM   479  C  CA  A ASN A 1 63  ? -22.271 -20.403 15.346  0.5 28.05  ? 59  ASN A CA  1 
ATOM   480  C  CA  B ASN A 1 63  ? -22.229 -20.403 15.388  0.5 28.44  ? 59  ASN A CA  1 
ATOM   481  C  C   A ASN A 1 63  ? -22.4   -21.846 14.857  0.5 28.16  ? 59  ASN A C   1 
ATOM   482  C  C   B ASN A 1 63  ? -22.358 -21.821 14.836  0.5 28.38  ? 59  ASN A C   1 
ATOM   483  O  O   A ASN A 1 63  ? -23.272 -22.162 14.047  0.5 31.86  ? 59  ASN A O   1 
ATOM   484  O  O   B ASN A 1 63  ? -23.191 -22.095 13.974  0.5 32.36  ? 59  ASN A O   1 
ATOM   485  C  CB  A ASN A 1 63  ? -23.51  -19.766 15.972  0.5 27.7   ? 59  ASN A CB  1 
ATOM   486  C  CB  B ASN A 1 63  ? -23.502 -19.911 16.078  0.5 28.47  ? 59  ASN A CB  1 
ATOM   487  C  CG  A ASN A 1 63  ? -23.321 -18.275 16.122  0.5 30.71  ? 59  ASN A CG  1 
ATOM   488  C  CG  B ASN A 1 63  ? -23.635 -20.46  17.481  0.5 32.19  ? 59  ASN A CG  1 
ATOM   489  O  OD1 A ASN A 1 63  ? -24.243 -17.495 15.863  0.5 32.64  ? 59  ASN A OD1 1 
ATOM   490  O  OD1 B ASN A 1 63  ? -22.659 -20.974 18.052  0.5 33.37  ? 59  ASN A OD1 1 
ATOM   491  N  ND2 A ASN A 1 63  ? -22.122 -17.855 16.507  0.5 30.77  ? 59  ASN A ND2 1 
ATOM   492  N  ND2 B ASN A 1 63  ? -24.827 -20.366 18.054  0.5 32.21  ? 59  ASN A ND2 1 
ATOM   493  N  N   . HIS A 1 64  ? -21.508 -22.714 15.34   1   25.57  ? 60  HIS A N   1 
ATOM   494  C  CA  . HIS A 1 64  ? -21.513 -24.107 14.94   1   25.17  ? 60  HIS A CA  1 
ATOM   495  C  C   . HIS A 1 64  ? -20.838 -24.95  16.031  1   26.64  ? 60  HIS A C   1 
ATOM   496  O  O   . HIS A 1 64  ? -19.834 -24.539 16.613  1   27.5   ? 60  HIS A O   1 
ATOM   497  C  CB  . HIS A 1 64  ? -20.872 -24.241 13.555  1   23.61  ? 60  HIS A CB  1 
ATOM   498  C  CG  . HIS A 1 64  ? -21.018 -25.619 13.027  1   26.36  ? 60  HIS A CG  1 
ATOM   499  N  ND1 . HIS A 1 64  ? -20.166 -26.638 13.413  1   26.16  ? 60  HIS A ND1 1 
ATOM   500  C  CD2 . HIS A 1 64  ? -21.906 -26.155 12.166  1   22.69  ? 60  HIS A CD2 1 
ATOM   501  C  CE1 . HIS A 1 64  ? -20.546 -27.756 12.798  1   25.88  ? 60  HIS A CE1 1 
ATOM   502  N  NE2 . HIS A 1 64  ? -21.598 -27.479 12.045  1   22.75  ? 60  HIS A NE2 1 
ATOM   503  N  N   . PRO A 1 65  ? -21.341 -26.165 16.358  1   26.36  ? 61  PRO A N   1 
ATOM   504  C  CA  . PRO A 1 65  ? -20.751 -26.965 17.424  1   24.68  ? 61  PRO A CA  1 
ATOM   505  C  C   . PRO A 1 65  ? -19.274 -27.281 17.221  1   26.01  ? 61  PRO A C   1 
ATOM   506  O  O   . PRO A 1 65  ? -18.604 -27.584 18.189  1   27.21  ? 61  PRO A O   1 
ATOM   507  C  CB  . PRO A 1 65  ? -21.556 -28.268 17.423  1   24.11  ? 61  PRO A CB  1 
ATOM   508  C  CG  . PRO A 1 65  ? -22.775 -28.016 16.621  1   24.44  ? 61  PRO A CG  1 
ATOM   509  C  CD  . PRO A 1 65  ? -22.516 -26.811 15.751  1   27.03  ? 61  PRO A CD  1 
ATOM   510  N  N   . ASN A 1 66  ? -18.786 -27.273 15.972  1   24.74  ? 62  ASN A N   1 
ATOM   511  C  CA  . ASN A 1 66  ? -17.408 -27.65  15.689  1   24.03  ? 62  ASN A CA  1 
ATOM   512  C  C   . ASN A 1 66  ? -16.574 -26.425 15.33   1   24.17  ? 62  ASN A C   1 
ATOM   513  O  O   . ASN A 1 66  ? -15.504 -26.536 14.736  1   24.91  ? 62  ASN A O   1 
ATOM   514  C  CB  . ASN A 1 66  ? -17.341 -28.718 14.605  1   23.56  ? 62  ASN A CB  1 
ATOM   515  C  CG  . ASN A 1 66  ? -18.087 -29.94  15.076  1   27.78  ? 62  ASN A CG  1 
ATOM   516  O  OD1 . ASN A 1 66  ? -19.175 -30.219 14.565  1   32.57  ? 62  ASN A OD1 1 
ATOM   517  N  ND2 . ASN A 1 66  ? -17.594 -30.62  16.109  1   24.4   ? 62  ASN A ND2 1 
ATOM   518  N  N   . ILE A 1 67  ? -17.084 -25.248 15.684  1   23.05  ? 63  ILE A N   1 
ATOM   519  C  CA  . ILE A 1 67  ? -16.296 -24.034 15.647  1   22.55  ? 63  ILE A CA  1 
ATOM   520  C  C   . ILE A 1 67  ? -16.33  -23.455 17.062  1   25.07  ? 63  ILE A C   1 
ATOM   521  O  O   . ILE A 1 67  ? -17.386 -23.367 17.687  1   30.76  ? 63  ILE A O   1 
ATOM   522  C  CB  . ILE A 1 67  ? -16.848 -23.061 14.595  1   19.86  ? 63  ILE A CB  1 
ATOM   523  C  CG1 . ILE A 1 67  ? -16.813 -23.681 13.199  1   21.87  ? 63  ILE A CG1 1 
ATOM   524  C  CG2 . ILE A 1 67  ? -16.055 -21.759 14.629  1   20.17  ? 63  ILE A CG2 1 
ATOM   525  C  CD1 . ILE A 1 67  ? -17.543 -22.896 12.106  1   19.25  ? 63  ILE A CD1 1 
ATOM   526  N  N   . VAL A 1 68  ? -15.157 -23.087 17.574  1   24.96  ? 64  VAL A N   1 
ATOM   527  C  CA  . VAL A 1 68  ? -15.031 -22.559 18.926  1   25.65  ? 64  VAL A CA  1 
ATOM   528  C  C   . VAL A 1 68  ? -15.854 -21.279 19.029  1   24.32  ? 64  VAL A C   1 
ATOM   529  O  O   . VAL A 1 68  ? -15.77  -20.401 18.175  1   25.77  ? 64  VAL A O   1 
ATOM   530  C  CB  . VAL A 1 68  ? -13.551 -22.275 19.236  1   25.86  ? 64  VAL A CB  1 
ATOM   531  C  CG1 . VAL A 1 68  ? -13.001 -21.181 18.286  1   28.33  ? 64  VAL A CG1 1 
ATOM   532  C  CG2 . VAL A 1 68  ? -13.352 -21.933 20.712  1   21.89  ? 64  VAL A CG2 1 
ATOM   533  N  N   . LYS A 1 69  ? -16.651 -21.187 20.09   1   27.05  ? 65  LYS A N   1 
ATOM   534  C  CA  . LYS A 1 69  ? -17.603 -20.095 20.229  1   26.52  ? 65  LYS A CA  1 
ATOM   535  C  C   . LYS A 1 69  ? -16.935 -18.878 20.863  1   27.07  ? 65  LYS A C   1 
ATOM   536  O  O   . LYS A 1 69  ? -16.316 -18.979 21.931  1   28.53  ? 65  LYS A O   1 
ATOM   537  C  CB  . LYS A 1 69  ? -18.851 -20.546 20.989  1   27.58  ? 65  LYS A CB  1 
ATOM   538  C  CG  . LYS A 1 69  ? -19.957 -19.509 20.959  1   35.69  ? 65  LYS A CG  1 
ATOM   539  C  CD  . LYS A 1 69  ? -21.297 -20.004 20.439  1   47.64  ? 65  LYS A CD  1 
ATOM   540  C  CE  . LYS A 1 69  ? -22.335 -18.915 20.348  1   51.08  ? 65  LYS A CE  1 
ATOM   541  N  NZ  . LYS A 1 69  ? -22.983 -18.827 21.655  1   65.4   ? 65  LYS A NZ  1 
ATOM   542  N  N   . LEU A 1 70  ? -17.084 -17.731 20.187  1   23.6   ? 66  LEU A N   1 
ATOM   543  C  CA  . LEU A 1 70  ? -16.826 -16.429 20.78   1   22.41  ? 66  LEU A CA  1 
ATOM   544  C  C   . LEU A 1 70  ? -18.049 -16.024 21.608  1   21.12  ? 66  LEU A C   1 
ATOM   545  O  O   . LEU A 1 70  ? -19.127 -15.843 21.063  1   22.31  ? 66  LEU A O   1 
ATOM   546  C  CB  . LEU A 1 70  ? -16.557 -15.463 19.624  1   22.41  ? 66  LEU A CB  1 
ATOM   547  C  CG  . LEU A 1 70  ? -16.202 -14.018 19.988  1   22.28  ? 66  LEU A CG  1 
ATOM   548  C  CD1 . LEU A 1 70  ? -15.111 -13.972 21.061  1   20.07  ? 66  LEU A CD1 1 
ATOM   549  C  CD2 . LEU A 1 70  ? -15.76  -13.278 18.714  1   21.24  ? 66  LEU A CD2 1 
ATOM   550  N  N   . LEU A 1 71  ? -17.89  -15.92  22.93   1   18.5   ? 67  LEU A N   1 
ATOM   551  C  CA  . LEU A 1 71  ? -18.986 -15.61  23.837  1   16.44  ? 67  LEU A CA  1 
ATOM   552  C  C   . LEU A 1 71  ? -19.202 -14.109 23.912  1   16.45  ? 67  LEU A C   1 
ATOM   553  O  O   . LEU A 1 71  ? -20.338 -13.643 23.967  1   17.05  ? 67  LEU A O   1 
ATOM   554  C  CB  . LEU A 1 71  ? -18.714 -16.213 25.216  1   15.41  ? 67  LEU A CB  1 
ATOM   555  C  CG  . LEU A 1 71  ? -18.423 -17.722 25.178  1   15.51  ? 67  LEU A CG  1 
ATOM   556  C  CD1 . LEU A 1 71  ? -18.149 -18.287 26.558  1   14.35  ? 67  LEU A CD1 1 
ATOM   557  C  CD2 . LEU A 1 71  ? -19.52  -18.505 24.434  1   13.25  ? 67  LEU A CD2 1 
ATOM   558  N  N   . ASP A 1 72  ? -18.097 -13.36  23.889  1   17.07  ? 68  ASP A N   1 
ATOM   559  C  CA  . ASP A 1 72  ? -18.137 -11.946 24.211  1   17.12  ? 68  ASP A CA  1 
ATOM   560  C  C   . ASP A 1 72  ? -16.838 -11.267 23.79   1   17.44  ? 68  ASP A C   1 
ATOM   561  O  O   . ASP A 1 72  ? -15.829 -11.938 23.508  1   15.73  ? 68  ASP A O   1 
ATOM   562  C  CB  . ASP A 1 72  ? -18.386 -11.714 25.692  1   18.16  ? 68  ASP A CB  1 
ATOM   563  C  CG  . ASP A 1 72  ? -19.075 -10.394 26.008  1   20.57  ? 68  ASP A CG  1 
ATOM   564  O  OD1 . ASP A 1 72  ? -19.318 -9.585  25.085  1   20.61  ? 68  ASP A OD1 1 
ATOM   565  O  OD2 . ASP A 1 72  ? -19.391 -10.196 27.178  1   22.03  ? 68  ASP A OD2 1 
ATOM   566  N  N   . VAL A 1 73  ? -16.903 -9.943  23.691  1   16.74  ? 69  VAL A N   1 
ATOM   567  C  CA  . VAL A 1 73  ? -15.71  -9.115  23.388  1   17.34  ? 69  VAL A CA  1 
ATOM   568  C  C   . VAL A 1 73  ? -15.816 -7.928  24.352  1   21.39  ? 69  VAL A C   1 
ATOM   569  O  O   . VAL A 1 73  ? -16.841 -7.236  24.336  1   24.9   ? 69  VAL A O   1 
ATOM   570  C  CB  . VAL A 1 73  ? -15.607 -8.644  21.927  1   17.31  ? 69  VAL A CB  1 
ATOM   571  C  CG1 . VAL A 1 73  ? -14.683 -7.443  21.779  1   16.73  ? 69  VAL A CG1 1 
ATOM   572  C  CG2 . VAL A 1 73  ? -15.161 -9.77   21.006  1   16.82  ? 69  VAL A CG2 1 
ATOM   573  N  N   . ILE A 1 74  ? -14.817 -7.753  25.205  1   23.58  ? 70  ILE A N   1 
ATOM   574  C  CA  . ILE A 1 74  ? -14.828 -6.614  26.163  1   24.87  ? 70  ILE A CA  1 
ATOM   575  C  C   . ILE A 1 74  ? -13.775 -5.583  25.728  1   29.2   ? 70  ILE A C   1 
ATOM   576  O  O   . ILE A 1 74  ? -12.598 -5.944  25.629  1   26.29  ? 70  ILE A O   1 
ATOM   577  C  CB  . ILE A 1 74  ? -14.662 -7.115  27.607  1   23.84  ? 70  ILE A CB  1 
ATOM   578  C  CG1 . ILE A 1 74  ? -15.743 -8.131  27.959  1   23.11  ? 70  ILE A CG1 1 
ATOM   579  C  CG2 . ILE A 1 74  ? -14.645 -5.951  28.593  1   22.95  ? 70  ILE A CG2 1 
ATOM   580  C  CD1 . ILE A 1 74  ? -15.305 -9.187  28.954  1   22.9   ? 70  ILE A CD1 1 
ATOM   581  N  N   . HIS A 1 75  ? -14.217 -4.362  25.429  1   40.5   ? 71  HIS A N   1 
ATOM   582  C  CA  . HIS A 1 75  ? -13.298 -3.272  25.015  1   50.91  ? 71  HIS A CA  1 
ATOM   583  C  C   . HIS A 1 75  ? -13.061 -2.355  26.207  1   55.46  ? 71  HIS A C   1 
ATOM   584  O  O   . HIS A 1 75  ? -13.93  -1.526  26.519  1   65.86  ? 71  HIS A O   1 
ATOM   585  C  CB  . HIS A 1 75  ? -13.866 -2.425  23.874  1   54.54  ? 71  HIS A CB  1 
ATOM   586  C  CG  . HIS A 1 75  ? -15.008 -3.008  23.119  1   64.35  ? 71  HIS A CG  1 
ATOM   587  N  ND1 . HIS A 1 75  ? -14.85  -3.663  21.92   1   74.38  ? 71  HIS A ND1 1 
ATOM   588  C  CD2 . HIS A 1 75  ? -16.32  -3.002  23.366  1   66.64  ? 71  HIS A CD2 1 
ATOM   589  C  CE1 . HIS A 1 75  ? -16.036 -4.055  21.481  1   74.23  ? 71  HIS A CE1 1 
ATOM   590  N  NE2 . HIS A 1 75  ? -16.942 -3.664  22.344  1   71.88  ? 71  HIS A NE2 1 
ATOM   591  N  N   . THR A 1 76  ? -11.914 -2.506  26.855  1   60.81  ? 72  THR A N   1 
ATOM   592  C  CA  . THR A 1 76  ? -11.601 -1.693  28.036  1   61.94  ? 72  THR A CA  1 
ATOM   593  C  C   . THR A 1 76  ? -10.634 -0.605  27.646  1   72.38  ? 72  THR A C   1 
ATOM   594  O  O   . THR A 1 76  ? -10.725 -0.093  26.501  1   62.98  ? 72  THR A O   1 
ATOM   595  C  CB  . THR A 1 76  ? -10.986 -2.602  29.088  1   59.96  ? 72  THR A CB  1 
ATOM   596  O  OG1 . THR A 1 76  ? -9.616  -2.715  28.722  1   68.2   ? 72  THR A OG1 1 
ATOM   597  C  CG2 . THR A 1 76  ? -11.612 -3.983  29.106  1   64.34  ? 72  THR A CG2 1 
ATOM   598  N  N   . GLU A 1 77  ? -9.738  -0.249  28.566  1   80.85  ? 73  GLU A N   1 
ATOM   599  C  CA  . GLU A 1 77  ? -8.711  0.775   28.275  1   79.13  ? 73  GLU A CA  1 
ATOM   600  C  C   . GLU A 1 77  ? -7.591  0.122   27.468  1   77.46  ? 73  GLU A C   1 
ATOM   601  O  O   . GLU A 1 77  ? -7.015  -0.86   27.963  1   84.08  ? 73  GLU A O   1 
ATOM   602  C  CB  . GLU A 1 77  ? -8.111  1.293   29.576  1   76.8   ? 73  GLU A CB  1 
ATOM   603  C  CG  . GLU A 1 77  ? -7.219  0.27    30.272  1   86.41  ? 73  GLU A CG  1 
ATOM   604  C  CD  . GLU A 1 77  ? -7.958  -0.803  31.052  1   90.59  ? 73  GLU A CD  1 
ATOM   605  O  OE1 . GLU A 1 77  ? -9.204  -0.826  30.99   1   96.23  ? 73  GLU A OE1 1 
ATOM   606  O  OE2 . GLU A 1 77  ? -7.289  -1.622  31.712  1   81.71  ? 73  GLU A OE2 1 
ATOM   607  N  N   . ASN A 1 78  ? -7.29   0.653   26.286  1   61.06  ? 74  ASN A N   1 
ATOM   608  C  CA  . ASN A 1 78  ? -6.139  0.136   25.501  1   55.77  ? 74  ASN A CA  1 
ATOM   609  C  C   . ASN A 1 78  ? -6.051  -1.384  25.628  1   51.36  ? 74  ASN A C   1 
ATOM   610  O  O   . ASN A 1 78  ? -4.934  -1.919  25.533  1   57.61  ? 74  ASN A O   1 
ATOM   611  C  CB  . ASN A 1 78  ? -4.837  0.824   25.901  1   61.83  ? 74  ASN A CB  1 
ATOM   612  C  CG  . ASN A 1 78  ? -4.407  0.573   27.324  1   67.01  ? 74  ASN A CG  1 
ATOM   613  O  OD1 . ASN A 1 78  ? -4.636  -0.517  27.859  1   71.55  ? 74  ASN A OD1 1 
ATOM   614  N  ND2 . ASN A 1 78  ? -3.788  1.562   27.952  1   63.85  ? 74  ASN A ND2 1 
ATOM   615  N  N   . LYS A 1 79  ? -7.196  -2.045  25.782  1   48.46  ? 75  LYS A N   1 
ATOM   616  C  CA  . LYS A 1 79  ? -7.207  -3.527  25.881  1   42.52  ? 75  LYS A CA  1 
ATOM   617  C  C   . LYS A 1 79  ? -8.488  -4.134  25.296  1   32.75  ? 75  LYS A C   1 
ATOM   618  O  O   . LYS A 1 79  ? -9.572  -3.569  25.501  1   32.02  ? 75  LYS A O   1 
ATOM   619  C  CB  . LYS A 1 79  ? -7.027  -3.979  27.331  1   47.98  ? 75  LYS A CB  1 
ATOM   620  C  CG  . LYS A 1 79  ? -5.675  -3.68   27.938  1   53.45  ? 75  LYS A CG  1 
ATOM   621  C  CD  . LYS A 1 79  ? -5.629  -4.154  29.383  1   60.16  ? 75  LYS A CD  1 
ATOM   622  C  CE  . LYS A 1 79  ? -4.297  -3.89   29.995  1   67.78  ? 75  LYS A CE  1 
ATOM   623  N  NZ  . LYS A 1 79  ? -4.268  -4.327  31.391  1   66.59  ? 75  LYS A NZ  1 
ATOM   624  N  N   . LEU A 1 80  ? -8.338  -5.247  24.59   1   25.36  ? 76  LEU A N   1 
ATOM   625  C  CA  . LEU A 1 80  ? -9.464  -5.967  24.032  1   23.65  ? 76  LEU A CA  1 
ATOM   626  C  C   . LEU A 1 80  ? -9.405  -7.41   24.53   1   24.05  ? 76  LEU A C   1 
ATOM   627  O  O   . LEU A 1 80  ? -8.421  -8.114  24.299  1   24.72  ? 76  LEU A O   1 
ATOM   628  C  CB  . LEU A 1 80  ? -9.309  -5.899  22.508  1   22.65  ? 76  LEU A CB  1 
ATOM   629  C  CG  . LEU A 1 80  ? -10.601 -5.899  21.689  1   21.5   ? 76  LEU A CG  1 
ATOM   630  C  CD1 . LEU A 1 80  ? -11.401 -4.632  22.077  1   24.05  ? 76  LEU A CD1 1 
ATOM   631  C  CD2 . LEU A 1 80  ? -10.204 -5.909  20.242  1   19.24  ? 76  LEU A CD2 1 
ATOM   632  N  N   . TYR A 1 81  ? -10.465 -7.867  25.205  1   24.77  ? 77  TYR A N   1 
ATOM   633  C  CA  . TYR A 1 81  ? -10.548 -9.259  25.636  1   23.57  ? 77  TYR A CA  1 
ATOM   634  C  C   . TYR A 1 81  ? -11.591 -10.008 24.819  1   22.51  ? 77  TYR A C   1 
ATOM   635  O  O   . TYR A 1 81  ? -12.765 -9.666  24.854  1   24.4   ? 77  TYR A O   1 
ATOM   636  C  CB  . TYR A 1 81  ? -10.996 -9.309  27.096  1   25.44  ? 77  TYR A CB  1 
ATOM   637  C  CG  . TYR A 1 81  ? -9.943  -8.833  28.083  1   28.63  ? 77  TYR A CG  1 
ATOM   638  C  CD1 . TYR A 1 81  ? -8.862  -9.65   28.418  1   29.12  ? 77  TYR A CD1 1 
ATOM   639  C  CD2 . TYR A 1 81  ? -10.018 -7.566  28.653  1   27.97  ? 77  TYR A CD2 1 
ATOM   640  C  CE1 . TYR A 1 81  ? -7.889  -9.225  29.309  1   30.2   ? 77  TYR A CE1 1 
ATOM   641  C  CE2 . TYR A 1 81  ? -9.061  -7.153  29.567  1   31.26  ? 77  TYR A CE2 1 
ATOM   642  C  CZ  . TYR A 1 81  ? -7.999  -7.978  29.905  1   31.43  ? 77  TYR A CZ  1 
ATOM   643  O  OH  . TYR A 1 81  ? -7.074  -7.515  30.813  1   35.07  ? 77  TYR A OH  1 
ATOM   644  N  N   . LEU A 1 82  ? -11.156 -11.033 24.086  1   22.16  ? 78  LEU A N   1 
ATOM   645  C  CA  . LEU A 1 82  ? -12.073 -11.983 23.475  1   22     ? 78  LEU A CA  1 
ATOM   646  C  C   . LEU A 1 82  ? -12.378 -13.095 24.481  1   22.9   ? 78  LEU A C   1 
ATOM   647  O  O   . LEU A 1 82  ? -11.464 -13.756 24.936  1   29.56  ? 78  LEU A O   1 
ATOM   648  C  CB  . LEU A 1 82  ? -11.456 -12.571 22.207  1   22.02  ? 78  LEU A CB  1 
ATOM   649  C  CG  . LEU A 1 82  ? -11.613 -11.789 20.897  1   22.94  ? 78  LEU A CG  1 
ATOM   650  C  CD1 . LEU A 1 82  ? -10.835 -10.493 21.04   1   20.79  ? 78  LEU A CD1 1 
ATOM   651  C  CD2 . LEU A 1 82  ? -11.252 -12.524 19.611  1   23.58  ? 78  LEU A CD2 1 
ATOM   652  N  N   . VAL A 1 83  ? -13.647 -13.306 24.843  1   21.39  ? 79  VAL A N   1 
ATOM   653  C  CA  . VAL A 1 83  ? -14.046 -14.385 25.743  1   18.21  ? 79  VAL A CA  1 
ATOM   654  C  C   . VAL A 1 83  ? -14.493 -15.567 24.892  1   18.45  ? 79  VAL A C   1 
ATOM   655  O  O   . VAL A 1 83  ? -15.426 -15.432 24.106  1   19.07  ? 79  VAL A O   1 
ATOM   656  C  CB  . VAL A 1 83  ? -15.22  -13.972 26.647  1   16.47  ? 79  VAL A CB  1 
ATOM   657  C  CG1 . VAL A 1 83  ? -15.545 -15.032 27.688  1   14.46  ? 79  VAL A CG1 1 
ATOM   658  C  CG2 . VAL A 1 83  ? -14.992 -12.608 27.274  1   16.19  ? 79  VAL A CG2 1 
ATOM   659  N  N   . PHE A 1 84  ? -13.854 -16.727 25.079  1   17.87  ? 80  PHE A N   1 
ATOM   660  C  CA  . PHE A 1 84  ? -14.141 -17.896 24.269  1   18.32  ? 80  PHE A CA  1 
ATOM   661  C  C   . PHE A 1 84  ? -14.616 -19.037 25.159  1   21.41  ? 80  PHE A C   1 
ATOM   662  O  O   . PHE A 1 84  ? -14.274 -19.127 26.336  1   26.11  ? 80  PHE A O   1 
ATOM   663  C  CB  . PHE A 1 84  ? -12.897 -18.351 23.522  1   17.16  ? 80  PHE A CB  1 
ATOM   664  C  CG  . PHE A 1 84  ? -12.422 -17.53  22.332  1   18.22  ? 80  PHE A CG  1 
ATOM   665  C  CD1 . PHE A 1 84  ? -12.919 -17.792 21.048  1   19.19  ? 80  PHE A CD1 1 
ATOM   666  C  CD2 . PHE A 1 84  ? -11.439 -16.547 22.475  1   17.18  ? 80  PHE A CD2 1 
ATOM   667  C  CE1 . PHE A 1 84  ? -12.456 -17.088 19.934  1   18.49  ? 80  PHE A CE1 1 
ATOM   668  C  CE2 . PHE A 1 84  ? -10.982 -15.852 21.36   1   19.25  ? 80  PHE A CE2 1 
ATOM   669  C  CZ  . PHE A 1 84  ? -11.465 -16.142 20.086  1   18.96  ? 80  PHE A CZ  1 
ATOM   670  N  N   . GLU A 1 85  ? -15.475 -19.872 24.589  1   21.37  ? 81  GLU A N   1 
ATOM   671  C  CA  . GLU A 1 85  ? -15.672 -21.233 25.035  1   22.21  ? 81  GLU A CA  1 
ATOM   672  C  C   . GLU A 1 85  ? -14.308 -21.858 25.316  1   24.95  ? 81  GLU A C   1 
ATOM   673  O  O   . GLU A 1 85  ? -13.391 -21.736 24.503  1   26.37  ? 81  GLU A O   1 
ATOM   674  C  CB  . GLU A 1 85  ? -16.295 -21.929 23.83   1   24.56  ? 81  GLU A CB  1 
ATOM   675  C  CG  . GLU A 1 85  ? -16.433 -23.433 23.991  1   30.24  ? 81  GLU A CG  1 
ATOM   676  C  CD  . GLU A 1 85  ? -16.922 -24.128 22.744  1   30.03  ? 81  GLU A CD  1 
ATOM   677  O  OE1 . GLU A 1 85  ? -17.289 -25.315 22.876  1   29.66  ? 81  GLU A OE1 1 
ATOM   678  O  OE2 . GLU A 1 85  ? -16.929 -23.488 21.676  1   30.69  ? 81  GLU A OE2 1 
ATOM   679  N  N   . PHE A 1 86  ? -14.19  -22.541 26.469  1   25.86  ? 82  PHE A N   1 
ATOM   680  C  CA  . PHE A 1 86  ? -12.937 -23.159 26.874  1   23.82  ? 82  PHE A CA  1 
ATOM   681  C  C   . PHE A 1 86  ? -12.896 -24.634 26.474  1   23.74  ? 82  PHE A C   1 
ATOM   682  O  O   . PHE A 1 86  ? -13.855 -25.353 26.717  1   23.36  ? 82  PHE A O   1 
ATOM   683  C  CB  . PHE A 1 86  ? -12.76  -23.075 28.391  1   22.22  ? 82  PHE A CB  1 
ATOM   684  C  CG  . PHE A 1 86  ? -11.575 -23.871 28.9    1   20.75  ? 82  PHE A CG  1 
ATOM   685  C  CD1 . PHE A 1 86  ? -10.279 -23.407 28.712  1   20.81  ? 82  PHE A CD1 1 
ATOM   686  C  CD2 . PHE A 1 86  ? -11.755 -25.104 29.521  1   20.98  ? 82  PHE A CD2 1 
ATOM   687  C  CE1 . PHE A 1 86  ? -9.187  -24.156 29.159  1   22.15  ? 82  PHE A CE1 1 
ATOM   688  C  CE2 . PHE A 1 86  ? -10.662 -25.838 29.99   1   20.45  ? 82  PHE A CE2 1 
ATOM   689  C  CZ  . PHE A 1 86  ? -9.38   -25.359 29.822  1   20.26  ? 82  PHE A CZ  1 
ATOM   690  N  N   . LEU A 1 87  ? -11.767 -25.044 25.901  1   27.02  ? 83  LEU A N   1 
ATOM   691  C  CA  . LEU A 1 87  ? -11.526 -26.459 25.538  1   27.53  ? 83  LEU A CA  1 
ATOM   692  C  C   . LEU A 1 87  ? -10.175 -26.813 26.169  1   28.81  ? 83  LEU A C   1 
ATOM   693  O  O   . LEU A 1 87  ? -9.241  -26.011 26.046  1   31.02  ? 83  LEU A O   1 
ATOM   694  C  CB  . LEU A 1 87  ? -11.582 -26.672 24.027  1   25.36  ? 83  LEU A CB  1 
ATOM   695  C  CG  . LEU A 1 87  ? -12.973 -26.572 23.394  1   29.23  ? 83  LEU A CG  1 
ATOM   696  C  CD1 . LEU A 1 87  ? -13.162 -25.237 22.703  1   29.26  ? 83  LEU A CD1 1 
ATOM   697  C  CD2 . LEU A 1 87  ? -13.233 -27.713 22.435  1   31.51  ? 83  LEU A CD2 1 
ATOM   698  N  N   . HIS A 1 88  ? -10.081 -27.961 26.826  1   30.87  ? 84  HIS A N   1 
ATOM   699  C  CA  . HIS A 1 88  ? -8.863  -28.303 27.608  1   30.54  ? 84  HIS A CA  1 
ATOM   700  C  C   . HIS A 1 88  ? -7.623  -28.559 26.757  1   29.74  ? 84  HIS A C   1 
ATOM   701  O  O   . HIS A 1 88  ? -6.519  -28.303 27.253  1   30.48  ? 84  HIS A O   1 
ATOM   702  C  CB  . HIS A 1 88  ? -9.152  -29.489 28.533  1   35.71  ? 84  HIS A CB  1 
ATOM   703  C  CG  . HIS A 1 88  ? -9.13   -30.841 27.906  1   44.59  ? 84  HIS A CG  1 
ATOM   704  N  ND1 . HIS A 1 88  ? -8.225  -31.809 28.277  1   47.54  ? 84  HIS A ND1 1 
ATOM   705  C  CD2 . HIS A 1 88  ? -9.901  -31.398 26.97   1   51.49  ? 84  HIS A CD2 1 
ATOM   706  C  CE1 . HIS A 1 88  ? -8.442  -32.904 27.567  1   52.8   ? 84  HIS A CE1 1 
ATOM   707  N  NE2 . HIS A 1 88  ? -9.455  -32.676 26.767  1   53.37  ? 84  HIS A NE2 1 
ATOM   708  N  N   . GLN A 1 89  ? -7.778  -29.02  25.525  1   26.49  ? 85  GLN A N   1 
ATOM   709  C  CA  . GLN A 1 89  ? -6.544  -29.375 24.798  1   27.14  ? 85  GLN A CA  1 
ATOM   710  C  C   . GLN A 1 89  ? -6.611  -29.147 23.3    1   25.81  ? 85  GLN A C   1 
ATOM   711  O  O   . GLN A 1 89  ? -7.7    -28.935 22.776  1   28.47  ? 85  GLN A O   1 
ATOM   712  C  CB  . GLN A 1 89  ? -6.288  -30.868 24.971  1   31.88  ? 85  GLN A CB  1 
ATOM   713  C  CG  . GLN A 1 89  ? -4.814  -31.254 25.009  1   35.12  ? 85  GLN A CG  1 
ATOM   714  C  CD  . GLN A 1 89  ? -4.599  -32.723 25.29   1   42.55  ? 85  GLN A CD  1 
ATOM   715  O  OE1 . GLN A 1 89  ? -3.497  -33.161 25.628  1   52.44  ? 85  GLN A OE1 1 
ATOM   716  N  NE2 . GLN A 1 89  ? -5.661  -33.501 25.162  1   50.6   ? 85  GLN A NE2 1 
ATOM   717  N  N   . ASP A 1 90  ? -5.446  -29.155 22.669  1   24.56  ? 86  ASP A N   1 
ATOM   718  C  CA  . ASP A 1 90  ? -5.406  -29.13  21.208  1   27.76  ? 86  ASP A CA  1 
ATOM   719  C  C   . ASP A 1 90  ? -5.037  -30.517 20.653  1   26.5   ? 86  ASP A C   1 
ATOM   720  O  O   . ASP A 1 90  ? -4.594  -31.389 21.384  1   23.21  ? 86  ASP A O   1 
ATOM   721  C  CB  . ASP A 1 90  ? -4.504  -28.036 20.665  1   28.06  ? 86  ASP A CB  1 
ATOM   722  C  CG  . ASP A 1 90  ? -3.024  -28.293 20.88   1   32.02  ? 86  ASP A CG  1 
ATOM   723  O  OD1 . ASP A 1 90  ? -2.504  -29.232 20.265  1   32.42  ? 86  ASP A OD1 1 
ATOM   724  O  OD2 . ASP A 1 90  ? -2.415  -27.582 21.686  1   39.9   ? 86  ASP A OD2 1 
ATOM   725  N  N   . LEU A 1 91  ? -5.213  -30.713 19.34   1   26.24  ? 87  LEU A N   1 
ATOM   726  C  CA  . LEU A 1 91  ? -5.059  -32.025 18.737  1   27.77  ? 87  LEU A CA  1 
ATOM   727  C  C   . LEU A 1 91  ? -3.583  -32.426 18.693  1   29.04  ? 87  LEU A C   1 
ATOM   728  O  O   . LEU A 1 91  ? -3.256  -33.609 18.848  1   29.27  ? 87  LEU A O   1 
ATOM   729  C  CB  . LEU A 1 91  ? -5.701  -32.031 17.352  1   26.33  ? 87  LEU A CB  1 
ATOM   730  C  CG  . LEU A 1 91  ? -5.499  -33.307 16.521  1   26.1   ? 87  LEU A CG  1 
ATOM   731  C  CD1 . LEU A 1 91  ? -6.287  -34.49  17.083  1   24.11  ? 87  LEU A CD1 1 
ATOM   732  C  CD2 . LEU A 1 91  ? -5.891  -33.081 15.074  1   26.01  ? 87  LEU A CD2 1 
ATOM   733  N  N   . LYS A 1 92  ? -2.703  -31.434 18.503  1   27.54  ? 88  LYS A N   1 
ATOM   734  C  CA  . LYS A 1 92  ? -1.269  -31.663 18.517  1   29.54  ? 88  LYS A CA  1 
ATOM   735  C  C   . LYS A 1 92  ? -0.802  -32.179 19.885  1   30.72  ? 88  LYS A C   1 
ATOM   736  O  O   . LYS A 1 92  ? -0.076  -33.165 19.944  1   33.78  ? 88  LYS A O   1 
ATOM   737  C  CB  . LYS A 1 92  ? -0.533  -30.441 17.965  1   31.18  ? 88  LYS A CB  1 
ATOM   738  C  CG  . LYS A 1 92  ? 0.901   -30.245 18.434  1   33.42  ? 88  LYS A CG  1 
ATOM   739  C  CD  . LYS A 1 92  ? 1.895   -31.319 18.006  1   38.17  ? 88  LYS A CD  1 
ATOM   740  C  CE  . LYS A 1 92  ? 1.701   -31.769 16.592  1   43.57  ? 88  LYS A CE  1 
ATOM   741  N  NZ  . LYS A 1 92  ? 2.886   -32.489 16.132  1   50.4   ? 88  LYS A NZ  1 
ATOM   742  N  N   . LYS A 1 93  ? -1.243  -31.566 20.988  1   27.99  ? 89  LYS A N   1 
ATOM   743  C  CA  . LYS A 1 93  ? -0.855  -32.033 22.308  1   28.58  ? 89  LYS A CA  1 
ATOM   744  C  C   . LYS A 1 93  ? -1.438  -33.417 22.585  1   28.86  ? 89  LYS A C   1 
ATOM   745  O  O   . LYS A 1 93  ? -0.816  -34.248 23.264  1   30.07  ? 89  LYS A O   1 
ATOM   746  C  CB  . LYS A 1 93  ? -1.234  -31.056 23.421  1   32.11  ? 89  LYS A CB  1 
ATOM   747  C  CG  . LYS A 1 93  ? -0.318  -29.848 23.501  1   44.94  ? 89  LYS A CG  1 
ATOM   748  C  CD  . LYS A 1 93  ? -0.746  -28.807 24.537  1   58.85  ? 89  LYS A CD  1 
ATOM   749  C  CE  . LYS A 1 93  ? -0.105  -27.462 24.309  1   59.74  ? 89  LYS A CE  1 
ATOM   750  N  NZ  . LYS A 1 93  ? -0.928  -26.353 24.805  1   62.24  ? 89  LYS A NZ  1 
ATOM   751  N  N   . PHE A 1 94  ? -2.646  -33.653 22.076  1   27.46  ? 90  PHE A N   1 
ATOM   752  C  CA  . PHE A 1 94  ? -3.297  -34.942 22.239  1   29.01  ? 90  PHE A CA  1 
ATOM   753  C  C   . PHE A 1 94  ? -2.487  -36.02  21.517  1   28.11  ? 90  PHE A C   1 
ATOM   754  O  O   . PHE A 1 94  ? -2.168  -37.039 22.111  1   26.08  ? 90  PHE A O   1 
ATOM   755  C  CB  . PHE A 1 94  ? -4.761  -34.871 21.793  1   30.45  ? 90  PHE A CB  1 
ATOM   756  C  CG  . PHE A 1 94  ? -5.468  -36.213 21.866  1   28.27  ? 90  PHE A CG  1 
ATOM   757  C  CD1 . PHE A 1 94  ? -5.561  -36.896 23.064  1   27.94  ? 90  PHE A CD1 1 
ATOM   758  C  CD2 . PHE A 1 94  ? -5.947  -36.816 20.716  1   27.94  ? 90  PHE A CD2 1 
ATOM   759  C  CE1 . PHE A 1 94  ? -6.161  -38.138 23.13   1   29.52  ? 90  PHE A CE1 1 
ATOM   760  C  CE2 . PHE A 1 94  ? -6.581  -38.04  20.787  1   32.5   ? 90  PHE A CE2 1 
ATOM   761  C  CZ  . PHE A 1 94  ? -6.687  -38.703 21.994  1   32.52  ? 90  PHE A CZ  1 
ATOM   762  N  N   . MET A 1 95  ? -2.122  -35.775 20.253  1   28.55  ? 91  MET A N   1 
ATOM   763  C  CA  . MET A 1 95  ? -1.326  -36.73  19.495  1   30.75  ? 91  MET A CA  1 
ATOM   764  C  C   . MET A 1 95  ? 0.022   -36.994 20.156  1   36.64  ? 91  MET A C   1 
ATOM   765  O  O   . MET A 1 95  ? 0.49    -38.13  20.139  1   43.5   ? 91  MET A O   1 
ATOM   766  C  CB  . MET A 1 95  ? -1.09   -36.26  18.062  1   29.07  ? 91  MET A CB  1 
ATOM   767  C  CG  . MET A 1 95  ? -2.206  -36.672 17.145  1   29.05  ? 91  MET A CG  1 
ATOM   768  S  SD  . MET A 1 95  ? -1.986  -35.962 15.508  1   43.04  ? 91  MET A SD  1 
ATOM   769  C  CE  . MET A 1 95  ? -1.754  -34.213 15.843  1   31.16  ? 91  MET A CE  1 
ATOM   770  N  N   . ASP A 1 96  ? 0.618   -35.962 20.767  1   38.02  ? 92  ASP A N   1 
ATOM   771  C  CA  . ASP A 1 96  ? 1.964   -36.051 21.31   1   36.89  ? 92  ASP A CA  1 
ATOM   772  C  C   . ASP A 1 96  ? 2       -36.861 22.593  1   39.16  ? 92  ASP A C   1 
ATOM   773  O  O   . ASP A 1 96  ? 2.907   -37.665 22.781  1   48.01  ? 92  ASP A O   1 
ATOM   774  C  CB  . ASP A 1 96  ? 2.568   -34.686 21.584  1   37.26  ? 92  ASP A CB  1 
ATOM   775  C  CG  . ASP A 1 96  ? 3.081   -33.959 20.351  1   44.03  ? 92  ASP A CG  1 
ATOM   776  O  OD1 . ASP A 1 96  ? 3.176   -34.609 19.264  1   42.09  ? 92  ASP A OD1 1 
ATOM   777  O  OD2 . ASP A 1 96  ? 3.349   -32.745 20.492  1   48.45  ? 92  ASP A OD2 1 
ATOM   778  N  N   . ALA A 1 97  ? 1.027   -36.635 23.477  1   43.62  ? 93  ALA A N   1 
ATOM   779  C  CA  . ALA A 1 97  ? 1.205   -37.038 24.862  1   48.39  ? 93  ALA A CA  1 
ATOM   780  C  C   . ALA A 1 97  ? 0.4     -38.295 25.19   1   50.79  ? 93  ALA A C   1 
ATOM   781  O  O   . ALA A 1 97  ? 0.761   -39.069 26.084  1   56.41  ? 93  ALA A O   1 
ATOM   782  C  CB  . ALA A 1 97  ? 0.874   -35.878 25.778  1   44.87  ? 93  ALA A CB  1 
ATOM   783  N  N   . SER A 1 98  ? -0.688  -38.509 24.463  1   50.02  ? 94  SER A N   1 
ATOM   784  C  CA  . SER A 1 98  ? -1.576  -39.631 24.849  1   57.68  ? 94  SER A CA  1 
ATOM   785  C  C   . SER A 1 98  ? -1.728  -40.632 23.703  1   54.7   ? 94  SER A C   1 
ATOM   786  O  O   . SER A 1 98  ? -2.11   -41.782 23.979  1   55.68  ? 94  SER A O   1 
ATOM   787  C  CB  . SER A 1 98  ? -2.914  -39.108 25.315  1   57.59  ? 94  SER A CB  1 
ATOM   788  O  OG  . SER A 1 98  ? -3.873  -40.149 25.432  1   61.82  ? 94  SER A OG  1 
ATOM   789  N  N   . ALA A 1 99  ? -1.443  -40.222 22.473  1   42.85  ? 95  ALA A N   1 
ATOM   790  C  CA  . ALA A 1 99  ? -1.68   -41.165 21.36   1   39.36  ? 95  ALA A CA  1 
ATOM   791  C  C   . ALA A 1 99  ? -0.389  -41.932 21.058  1   46.12  ? 95  ALA A C   1 
ATOM   792  O  O   . ALA A 1 99  ? -0.216  -42.415 19.954  1   48.51  ? 95  ALA A O   1 
ATOM   793  C  CB  . ALA A 1 99  ? -2.241  -40.424 20.189  1   29.73  ? 95  ALA A CB  1 
ATOM   794  N  N   . LEU A 1 100 ? 0.456   -42.12  22.063  1   54.86  ? 96  LEU A N   1 
ATOM   795  C  CA  . LEU A 1 100 ? 1.735   -42.854 21.918  1   63.36  ? 96  LEU A CA  1 
ATOM   796  C  C   . LEU A 1 100 ? 1.601   -44.078 21.005  1   69.45  ? 96  LEU A C   1 
ATOM   797  O  O   . LEU A 1 100 ? 2.27    -44.09  19.958  1   77.29  ? 96  LEU A O   1 
ATOM   798  C  CB  . LEU A 1 100 ? 2.057   -43.23  23.354  1   70.39  ? 96  LEU A CB  1 
ATOM   799  C  CG  . LEU A 1 100 ? 1.904   -42.096 24.372  1   80.28  ? 96  LEU A CG  1 
ATOM   800  C  CD1 . LEU A 1 100 ? 2.175   -42.59  25.779  1   79.07  ? 96  LEU A CD1 1 
ATOM   801  C  CD2 . LEU A 1 100 ? 2.831   -40.944 24.023  1   88.15  ? 96  LEU A CD2 1 
ATOM   802  N  N   . THR A 1 101 ? 0.742   -45.029 21.379  1   69.76  ? 97  THR A N   1 
ATOM   803  C  CA  . THR A 1 101 ? 0.527   -46.264 20.595  1   66.74  ? 97  THR A CA  1 
ATOM   804  C  C   . THR A 1 101 ? -0.509  -46.038 19.518  1   64.6   ? 97  THR A C   1 
ATOM   805  O  O   . THR A 1 101 ? -0.873  -47.018 18.847  1   85.91  ? 97  THR A O   1 
ATOM   806  C  CB  . THR A 1 101 ? 0.086   -47.359 21.562  1   65.83  ? 97  THR A CB  1 
ATOM   807  O  OG1 . THR A 1 101 ? -1.107  -46.905 22.19   1   72.06  ? 97  THR A OG1 1 
ATOM   808  C  CG2 . THR A 1 101 ? 1.12    -47.632 22.639  1   59.62  ? 97  THR A CG2 1 
ATOM   809  N  N   . GLY A 1 102 ? -1.031  -44.821 19.388  1   52.33  ? 98  GLY A N   1 
ATOM   810  C  CA  . GLY A 1 102 ? -1.947  -44.538 18.273  1   42.26  ? 98  GLY A CA  1 
ATOM   811  C  C   . GLY A 1 102 ? -3.256  -43.901 18.665  1   40.82  ? 98  GLY A C   1 
ATOM   812  O  O   . GLY A 1 102 ? -3.567  -43.873 19.865  1   36.3   ? 98  GLY A O   1 
ATOM   813  N  N   . ILE A 1 103 ? -3.975  -43.362 17.68   1   41.08  ? 99  ILE A N   1 
ATOM   814  C  CA  . ILE A 1 103 ? -5.348  -42.844 17.933  1   33.92  ? 99  ILE A CA  1 
ATOM   815  C  C   . ILE A 1 103 ? -6.293  -43.926 17.399  1   30.18  ? 99  ILE A C   1 
ATOM   816  O  O   . ILE A 1 103 ? -6.063  -44.398 16.28   1   32.95  ? 99  ILE A O   1 
ATOM   817  C  CB  . ILE A 1 103 ? -5.597  -41.49  17.245  1   33.88  ? 99  ILE A CB  1 
ATOM   818  C  CG1 . ILE A 1 103 ? -4.523  -40.466 17.578  1   33.37  ? 99  ILE A CG1 1 
ATOM   819  C  CG2 . ILE A 1 103 ? -6.992  -40.956 17.57   1   34.77  ? 99  ILE A CG2 1 
ATOM   820  C  CD1 . ILE A 1 103 ? -4.957  -39.033 17.341  1   29.22  ? 99  ILE A CD1 1 
ATOM   821  N  N   . PRO A 1 104 ? -7.312  -44.372 18.152  1   25.9   ? 100 PRO A N   1 
ATOM   822  C  CA  . PRO A 1 104 ? -8.19   -45.445 17.665  1   23.97  ? 100 PRO A CA  1 
ATOM   823  C  C   . PRO A 1 104 ? -9.008  -44.968 16.472  1   25.94  ? 100 PRO A C   1 
ATOM   824  O  O   . PRO A 1 104 ? -9.453  -43.816 16.421  1   26.05  ? 100 PRO A O   1 
ATOM   825  C  CB  . PRO A 1 104 ? -9.083  -45.82  18.842  1   22.95  ? 100 PRO A CB  1 
ATOM   826  C  CG  . PRO A 1 104 ? -8.527  -45.031 20.013  1   22.94  ? 100 PRO A CG  1 
ATOM   827  C  CD  . PRO A 1 104 ? -7.706  -43.861 19.471  1   22.58  ? 100 PRO A CD  1 
ATOM   828  N  N   . LEU A 1 105 ? -9.17   -45.872 15.503  1   28.08  ? 101 LEU A N   1 
ATOM   829  C  CA  . LEU A 1 105 ? -9.858  -45.592 14.252  1   27.4   ? 101 LEU A CA  1 
ATOM   830  C  C   . LEU A 1 105 ? -11.204 -44.909 14.529  1   29.01  ? 101 LEU A C   1 
ATOM   831  O  O   . LEU A 1 105 ? -11.489 -43.887 13.909  1   29.35  ? 101 LEU A O   1 
ATOM   832  C  CB  . LEU A 1 105 ? -10.034 -46.893 13.475  1   24.24  ? 101 LEU A CB  1 
ATOM   833  C  CG  . LEU A 1 105 ? -10.806 -46.812 12.154  1   24.73  ? 101 LEU A CG  1 
ATOM   834  C  CD1 . LEU A 1 105 ? -10.03  -45.924 11.22   1   27.43  ? 101 LEU A CD1 1 
ATOM   835  C  CD2 . LEU A 1 105 ? -11.174 -48.127 11.481  1   23.16  ? 101 LEU A CD2 1 
ATOM   836  N  N   . PRO A 1 106 ? -12.065 -45.409 15.463  1   27.55  ? 102 PRO A N   1 
ATOM   837  C  CA  . PRO A 1 106 ? -13.297 -44.714 15.849  1   26.27  ? 102 PRO A CA  1 
ATOM   838  C  C   . PRO A 1 106 ? -13.137 -43.216 16.069  1   28.9   ? 102 PRO A C   1 
ATOM   839  O  O   . PRO A 1 106 ? -13.953 -42.444 15.557  1   31.27  ? 102 PRO A O   1 
ATOM   840  C  CB  . PRO A 1 106 ? -13.722 -45.42  17.137  1   25.04  ? 102 PRO A CB  1 
ATOM   841  C  CG  . PRO A 1 106 ? -13.262 -46.844 16.914  1   24.23  ? 102 PRO A CG  1 
ATOM   842  C  CD  . PRO A 1 106 ? -11.935 -46.69  16.177  1   25.26  ? 102 PRO A CD  1 
ATOM   843  N  N   . LEU A 1 107 ? -12.1   -42.828 16.835  1   28.01  ? 103 LEU A N   1 
ATOM   844  C  CA  . LEU A 1 107 ? -11.885 -41.446 17.245  1   23.65  ? 103 LEU A CA  1 
ATOM   845  C  C   . LEU A 1 107 ? -11.362 -40.61  16.077  1   23.6   ? 103 LEU A C   1 
ATOM   846  O  O   . LEU A 1 107 ? -11.694 -39.425 15.989  1   23.9   ? 103 LEU A O   1 
ATOM   847  C  CB  . LEU A 1 107 ? -10.92  -41.462 18.428  1   25.08  ? 103 LEU A CB  1 
ATOM   848  C  CG  . LEU A 1 107 ? -10.81  -40.208 19.309  1   26.27  ? 103 LEU A CG  1 
ATOM   849  C  CD1 . LEU A 1 107 ? -12.161 -39.601 19.689  1   26.04  ? 103 LEU A CD1 1 
ATOM   850  C  CD2 . LEU A 1 107 ? -10.079 -40.612 20.609  1   24.08  ? 103 LEU A CD2 1 
ATOM   851  N  N   . ILE A 1 108 ? -10.553 -41.214 15.181  1   23.81  ? 104 ILE A N   1 
ATOM   852  C  CA  . ILE A 1 108 ? -9.975  -40.492 14.048  1   23.06  ? 104 ILE A CA  1 
ATOM   853  C  C   . ILE A 1 108 ? -11.133 -40.079 13.151  1   23.89  ? 104 ILE A C   1 
ATOM   854  O  O   . ILE A 1 108 ? -11.262 -38.913 12.75   1   26.22  ? 104 ILE A O   1 
ATOM   855  C  CB  . ILE A 1 108 ? -8.937  -41.349 13.291  1   24.34  ? 104 ILE A CB  1 
ATOM   856  C  CG1 . ILE A 1 108 ? -7.684  -41.576 14.133  1   25.16  ? 104 ILE A CG1 1 
ATOM   857  C  CG2 . ILE A 1 108 ? -8.563  -40.716 11.948  1   23.53  ? 104 ILE A CG2 1 
ATOM   858  C  CD1 . ILE A 1 108 ? -6.606  -42.423 13.472  1   22.1   ? 104 ILE A CD1 1 
ATOM   859  N  N   . LYS A 1 109 ? -12.006 -41.069 12.932  1   21.98  ? 105 LYS A N   1 
ATOM   860  C  CA  . LYS A 1 109 ? -13.192 -40.987 12.101  1   21.64  ? 105 LYS A CA  1 
ATOM   861  C  C   . LYS A 1 109 ? -14.14  -39.931 12.65   1   24.01  ? 105 LYS A C   1 
ATOM   862  O  O   . LYS A 1 109 ? -14.572 -39.032 11.93   1   26.19  ? 105 LYS A O   1 
ATOM   863  C  CB  . LYS A 1 109 ? -13.784 -42.393 12.136  1   20.32  ? 105 LYS A CB  1 
ATOM   864  C  CG  . LYS A 1 109 ? -14.498 -42.787 10.883  1   23.19  ? 105 LYS A CG  1 
ATOM   865  C  CD  . LYS A 1 109 ? -14.789 -44.284 10.943  1   23.07  ? 105 LYS A CD  1 
ATOM   866  C  CE  . LYS A 1 109 ? -13.664 -45.086 10.426  1   23.51  ? 105 LYS A CE  1 
ATOM   867  N  NZ  . LYS A 1 109 ? -14.093 -46.42  9.984   1   23.29  ? 105 LYS A NZ  1 
ATOM   868  N  N   . SER A 1 110 ? -14.417 -40.018 13.951  1   24.81  ? 106 SER A N   1 
ATOM   869  C  CA  . SER A 1 110 ? -15.222 -39.02  14.633  1   24.93  ? 106 SER A CA  1 
ATOM   870  C  C   . SER A 1 110 ? -14.638 -37.616 14.499  1   24.07  ? 106 SER A C   1 
ATOM   871  O  O   . SER A 1 110 ? -15.379 -36.666 14.24   1   23.82  ? 106 SER A O   1 
ATOM   872  C  CB  . SER A 1 110 ? -15.456 -39.384 16.066  1   24.92  ? 106 SER A CB  1 
ATOM   873  O  OG  . SER A 1 110 ? -16.174 -38.325 16.669  1   27.71  ? 106 SER A OG  1 
ATOM   874  N  N   . TYR A 1 111 ? -13.321 -37.488 14.684  1   24.62  ? 107 TYR A N   1 
ATOM   875  C  CA  . TYR A 1 111 ? -12.698 -36.17  14.672  1   26.72  ? 107 TYR A CA  1 
ATOM   876  C  C   . TYR A 1 111 ? -12.721 -35.6   13.257  1   27.21  ? 107 TYR A C   1 
ATOM   877  O  O   . TYR A 1 111 ? -13.057 -34.432 13.063  1   27.78  ? 107 TYR A O   1 
ATOM   878  C  CB  . TYR A 1 111 ? -11.257 -36.231 15.183  1   29.8   ? 107 TYR A CB  1 
ATOM   879  C  CG  . TYR A 1 111 ? -11.072 -36.232 16.696  1   35.3   ? 107 TYR A CG  1 
ATOM   880  C  CD1 . TYR A 1 111 ? -12.148 -36.046 17.573  1   35.2   ? 107 TYR A CD1 1 
ATOM   881  C  CD2 . TYR A 1 111 ? -9.803  -36.4   17.247  1   32.62  ? 107 TYR A CD2 1 
ATOM   882  C  CE1 . TYR A 1 111 ? -11.958 -36.028 18.947  1   32.96  ? 107 TYR A CE1 1 
ATOM   883  C  CE2 . TYR A 1 111 ? -9.602  -36.364 18.616  1   30.98  ? 107 TYR A CE2 1 
ATOM   884  C  CZ  . TYR A 1 111 ? -10.678 -36.165 19.461  1   32.08  ? 107 TYR A CZ  1 
ATOM   885  O  OH  . TYR A 1 111 ? -10.483 -36.149 20.802  1   31.15  ? 107 TYR A OH  1 
ATOM   886  N  N   . LEU A 1 112 ? -12.336 -36.429 12.274  1   25.57  ? 108 LEU A N   1 
ATOM   887  C  CA  . LEU A 1 112 ? -12.284 -35.967 10.902  1   24.26  ? 108 LEU A CA  1 
ATOM   888  C  C   . LEU A 1 112 ? -13.683 -35.516 10.477  1   25.63  ? 108 LEU A C   1 
ATOM   889  O  O   . LEU A 1 112 ? -13.855 -34.511 9.786   1   27.81  ? 108 LEU A O   1 
ATOM   890  C  CB  . LEU A 1 112 ? -11.735 -37.067 9.994   1   21.02  ? 108 LEU A CB  1 
ATOM   891  C  CG  . LEU A 1 112 ? -11.587 -36.653 8.526   1   18.4   ? 108 LEU A CG  1 
ATOM   892  C  CD1 . LEU A 1 112 ? -10.764 -35.371 8.386   1   14.34  ? 108 LEU A CD1 1 
ATOM   893  C  CD2 . LEU A 1 112 ? -11.032 -37.79  7.691   1   16.86  ? 108 LEU A CD2 1 
ATOM   894  N  N   . PHE A 1 113 ? -14.695 -36.274 10.902  1   25.65  ? 109 PHE A N   1 
ATOM   895  C  CA  . PHE A 1 113 ? -16.062 -35.987 10.514  1   24.38  ? 109 PHE A CA  1 
ATOM   896  C  C   . PHE A 1 113 ? -16.553 -34.674 11.12   1   27.38  ? 109 PHE A C   1 
ATOM   897  O  O   . PHE A 1 113 ? -17.278 -33.939 10.452  1   33.13  ? 109 PHE A O   1 
ATOM   898  C  CB  . PHE A 1 113 ? -16.908 -37.175 10.947  1   24.07  ? 109 PHE A CB  1 
ATOM   899  C  CG  . PHE A 1 113 ? -18.322 -37.146 10.398  1   24.02  ? 109 PHE A CG  1 
ATOM   900  C  CD1 . PHE A 1 113 ? -18.539 -37.281 9.031   1   22.71  ? 109 PHE A CD1 1 
ATOM   901  C  CD2 . PHE A 1 113 ? -19.412 -36.991 11.247  1   22.21  ? 109 PHE A CD2 1 
ATOM   902  C  CE1 . PHE A 1 113 ? -19.82  -37.284 8.515   1   21.64  ? 109 PHE A CE1 1 
ATOM   903  C  CE2 . PHE A 1 113 ? -20.694 -37.002 10.73   1   22.41  ? 109 PHE A CE2 1 
ATOM   904  C  CZ  . PHE A 1 113 ? -20.894 -37.168 9.374   1   22.83  ? 109 PHE A CZ  1 
ATOM   905  N  N   . GLN A 1 114 ? -16.163 -34.371 12.372  1   27.2   ? 110 GLN A N   1 
ATOM   906  C  CA  . GLN A 1 114 ? -16.534 -33.11  12.998  1   24.79  ? 110 GLN A CA  1 
ATOM   907  C  C   . GLN A 1 114 ? -15.792 -31.973 12.3    1   25.29  ? 110 GLN A C   1 
ATOM   908  O  O   . GLN A 1 114 ? -16.351 -30.905 12.065  1   26.85  ? 110 GLN A O   1 
ATOM   909  C  CB  . GLN A 1 114 ? -16.248 -33.119 14.498  1   24.37  ? 110 GLN A CB  1 
ATOM   910  C  CG  . GLN A 1 114 ? -17.146 -34.04  15.317  1   25.09  ? 110 GLN A CG  1 
ATOM   911  C  CD  . GLN A 1 114 ? -16.728 -34.07  16.773  1   28.22  ? 110 GLN A CD  1 
ATOM   912  O  OE1 . GLN A 1 114 ? -16.882 -33.074 17.498  1   30.85  ? 110 GLN A OE1 1 
ATOM   913  N  NE2 . GLN A 1 114 ? -16.171 -35.2   17.211  1   24.63  ? 110 GLN A NE2 1 
ATOM   914  N  N   . LEU A 1 115 ? -14.521 -32.193 11.955  1   23.86  ? 111 LEU A N   1 
ATOM   915  C  CA  . LEU A 1 115 ? -13.761 -31.112 11.347  1   23.97  ? 111 LEU A CA  1 
ATOM   916  C  C   . LEU A 1 115 ? -14.395 -30.702 10.022  1   26.02  ? 111 LEU A C   1 
ATOM   917  O  O   . LEU A 1 115 ? -14.483 -29.514 9.716   1   23.66  ? 111 LEU A O   1 
ATOM   918  C  CB  . LEU A 1 115 ? -12.323 -31.552 11.154  1   23.84  ? 111 LEU A CB  1 
ATOM   919  C  CG  . LEU A 1 115 ? -11.542 -31.782 12.449  1   24.69  ? 111 LEU A CG  1 
ATOM   920  C  CD1 . LEU A 1 115 ? -10.184 -32.347 12.103  1   22.7   ? 111 LEU A CD1 1 
ATOM   921  C  CD2 . LEU A 1 115 ? -11.41  -30.444 13.151  1   23.76  ? 111 LEU A CD2 1 
ATOM   922  N  N   . LEU A 1 116 ? -14.854 -31.703 9.25    1   26.99  ? 112 LEU A N   1 
ATOM   923  C  CA  . LEU A 1 116 ? -15.493 -31.463 7.963   1   25.4   ? 112 LEU A CA  1 
ATOM   924  C  C   . LEU A 1 116 ? -16.814 -30.731 8.161   1   26.57  ? 112 LEU A C   1 
ATOM   925  O  O   . LEU A 1 116 ? -17.144 -29.871 7.345   1   30.71  ? 112 LEU A O   1 
ATOM   926  C  CB  . LEU A 1 116 ? -15.68  -32.753 7.175   1   23.66  ? 112 LEU A CB  1 
ATOM   927  C  CG  . LEU A 1 116 ? -14.379 -33.37  6.659   1   24.29  ? 112 LEU A CG  1 
ATOM   928  C  CD1 . LEU A 1 116 ? -14.553 -34.872 6.438   1   23.32  ? 112 LEU A CD1 1 
ATOM   929  C  CD2 . LEU A 1 116 ? -13.875 -32.655 5.411   1   24.65  ? 112 LEU A CD2 1 
ATOM   930  N  N   . GLN A 1 117 ? -17.548 -31.069 9.233   1   22.42  ? 113 GLN A N   1 
ATOM   931  C  CA  . GLN A 1 117 ? -18.77  -30.36  9.534   1   22.56  ? 113 GLN A CA  1 
ATOM   932  C  C   . GLN A 1 117 ? -18.518 -28.871 9.752   1   25.91  ? 113 GLN A C   1 
ATOM   933  O  O   . GLN A 1 117 ? -19.203 -28.03  9.149   1   25.94  ? 113 GLN A O   1 
ATOM   934  C  CB  . GLN A 1 117 ? -19.465 -30.918 10.761  1   22.74  ? 113 GLN A CB  1 
ATOM   935  C  CG  . GLN A 1 117 ? -20.103 -32.264 10.489  1   22.48  ? 113 GLN A CG  1 
ATOM   936  C  CD  . GLN A 1 117 ? -20.829 -32.775 11.699  1   21.19  ? 113 GLN A CD  1 
ATOM   937  O  OE1 . GLN A 1 117 ? -21.733 -32.129 12.232  1   21.11  ? 113 GLN A OE1 1 
ATOM   938  N  NE2 . GLN A 1 117 ? -20.437 -33.96  12.123  1   24.67  ? 113 GLN A NE2 1 
ATOM   939  N  N   . GLY A 1 118 ? -17.521 -28.556 10.593  1   26.05  ? 114 GLY A N   1 
ATOM   940  C  CA  . GLY A 1 118 ? -17.211 -27.171 10.904  1   24.65  ? 114 GLY A CA  1 
ATOM   941  C  C   . GLY A 1 118 ? -16.639 -26.417 9.703   1   25.38  ? 114 GLY A C   1 
ATOM   942  O  O   . GLY A 1 118 ? -16.921 -25.235 9.506   1   25.77  ? 114 GLY A O   1 
ATOM   943  N  N   . LEU A 1 119 ? -15.793 -27.087 8.925   1   24.29  ? 115 LEU A N   1 
ATOM   944  C  CA  . LEU A 1 119 ? -15.217 -26.449 7.758   1   26.2   ? 115 LEU A CA  1 
ATOM   945  C  C   . LEU A 1 119 ? -16.309 -26.207 6.711   1   28.09  ? 115 LEU A C   1 
ATOM   946  O  O   . LEU A 1 119 ? -16.322 -25.152 6.052   1   28.56  ? 115 LEU A O   1 
ATOM   947  C  CB  . LEU A 1 119 ? -14.063 -27.288 7.217   1   24.95  ? 115 LEU A CB  1 
ATOM   948  C  CG  . LEU A 1 119 ? -13.355 -26.686 6.004   1   27.11  ? 115 LEU A CG  1 
ATOM   949  C  CD1 . LEU A 1 119 ? -12.72  -25.337 6.37    1   27.19  ? 115 LEU A CD1 1 
ATOM   950  C  CD2 . LEU A 1 119 ? -12.335 -27.673 5.462   1   27.51  ? 115 LEU A CD2 1 
ATOM   951  N  N   . ALA A 1 120 ? -17.239 -27.169 6.571   1   24.14  ? 116 ALA A N   1 
ATOM   952  C  CA  . ALA A 1 120 ? -18.298 -26.974 5.591   1   23.69  ? 116 ALA A CA  1 
ATOM   953  C  C   . ALA A 1 120 ? -19.139 -25.758 5.992   1   24.28  ? 116 ALA A C   1 
ATOM   954  O  O   . ALA A 1 120 ? -19.562 -24.976 5.141   1   24.31  ? 116 ALA A O   1 
ATOM   955  C  CB  . ALA A 1 120 ? -19.133 -28.221 5.393   1   19.84  ? 116 ALA A CB  1 
ATOM   956  N  N   . PHE A 1 121 ? -19.385 -25.612 7.301   1   23.23  ? 117 PHE A N   1 
ATOM   957  C  CA  . PHE A 1 121 ? -20.099 -24.461 7.818   1   23.14  ? 117 PHE A CA  1 
ATOM   958  C  C   . PHE A 1 121 ? -19.314 -23.177 7.532   1   23.34  ? 117 PHE A C   1 
ATOM   959  O  O   . PHE A 1 121 ? -19.924 -22.168 7.195   1   26.79  ? 117 PHE A O   1 
ATOM   960  C  CB  . PHE A 1 121 ? -20.35  -24.614 9.316   1   22.37  ? 117 PHE A CB  1 
ATOM   961  C  CG  . PHE A 1 121 ? -21.294 -23.559 9.85    1   22.78  ? 117 PHE A CG  1 
ATOM   962  C  CD1 . PHE A 1 121 ? -22.665 -23.776 9.857   1   23.95  ? 117 PHE A CD1 1 
ATOM   963  C  CD2 . PHE A 1 121 ? -20.817 -22.322 10.285  1   25.02  ? 117 PHE A CD2 1 
ATOM   964  C  CE1 . PHE A 1 121 ? -23.542 -22.804 10.352  1   24.38  ? 117 PHE A CE1 1 
ATOM   965  C  CE2 . PHE A 1 121 ? -21.694 -21.343 10.748  1   23.48  ? 117 PHE A CE2 1 
ATOM   966  C  CZ  . PHE A 1 121 ? -23.053 -21.593 10.804  1   22.62  ? 117 PHE A CZ  1 
ATOM   967  N  N   . CYS A 1 122 ? -17.978 -23.224 7.625   1   20.56  ? 118 CYS A N   1 
ATOM   968  C  CA  . CYS A 1 122 ? -17.167 -22.069 7.28    1   24.15  ? 118 CYS A CA  1 
ATOM   969  C  C   . CYS A 1 122 ? -17.369 -21.67  5.821   1   24.31  ? 118 CYS A C   1 
ATOM   970  O  O   . CYS A 1 122 ? -17.663 -20.524 5.533   1   23.12  ? 118 CYS A O   1 
ATOM   971  C  CB  . CYS A 1 122 ? -15.68  -22.291 7.506   1   25.63  ? 118 CYS A CB  1 
ATOM   972  S  SG  . CYS A 1 122 ? -15.222 -22.316 9.255   1   33.9   ? 118 CYS A SG  1 
ATOM   973  N  N   . HIS A 1 123 ? -17.209 -22.63  4.909   1   25.56  ? 119 HIS A N   1 
ATOM   974  C  CA  . HIS A 1 123 ? -17.287 -22.365 3.485   1   22.42  ? 119 HIS A CA  1 
ATOM   975  C  C   . HIS A 1 123 ? -18.695 -21.905 3.111   1   23.25  ? 119 HIS A C   1 
ATOM   976  O  O   . HIS A 1 123 ? -18.868 -21.036 2.256   1   22.89  ? 119 HIS A O   1 
ATOM   977  C  CB  . HIS A 1 123 ? -16.789 -23.601 2.742   1   21.8   ? 119 HIS A CB  1 
ATOM   978  C  CG  . HIS A 1 123 ? -15.356 -23.892 3.023   1   23.57  ? 119 HIS A CG  1 
ATOM   979  N  ND1 . HIS A 1 123 ? -14.752 -25.085 2.664   1   25.77  ? 119 HIS A ND1 1 
ATOM   980  C  CD2 . HIS A 1 123 ? -14.392 -23.135 3.595   1   22.56  ? 119 HIS A CD2 1 
ATOM   981  C  CE1 . HIS A 1 123 ? -13.457 -25.033 3.013   1   26.28  ? 119 HIS A CE1 1 
ATOM   982  N  NE2 . HIS A 1 123 ? -13.215 -23.854 3.575   1   23.83  ? 119 HIS A NE2 1 
ATOM   983  N  N   . SER A 1 124 ? -19.7   -22.488 3.76    1   24.15  ? 120 SER A N   1 
ATOM   984  C  CA  . SER A 1 124 ? -21.091 -22.124 3.557   1   26.56  ? 120 SER A CA  1 
ATOM   985  C  C   . SER A 1 124 ? -21.393 -20.679 3.963   1   24.72  ? 120 SER A C   1 
ATOM   986  O  O   . SER A 1 124 ? -22.433 -20.156 3.561   1   24.37  ? 120 SER A O   1 
ATOM   987  C  CB  . SER A 1 124 ? -21.981 -23.055 4.32    1   29.28  ? 120 SER A CB  1 
ATOM   988  O  OG  . SER A 1 124 ? -21.932 -24.317 3.689   1   34.35  ? 120 SER A OG  1 
ATOM   989  N  N   . HIS A 1 125 ? -20.527 -20.088 4.803   1   22.81  ? 121 HIS A N   1 
ATOM   990  C  CA  . HIS A 1 125 ? -20.663 -18.732 5.316   1   22.15  ? 121 HIS A CA  1 
ATOM   991  C  C   . HIS A 1 125 ? -19.533 -17.865 4.77    1   24.02  ? 121 HIS A C   1 
ATOM   992  O  O   . HIS A 1 125 ? -19.201 -16.851 5.366   1   29.57  ? 121 HIS A O   1 
ATOM   993  C  CB  . HIS A 1 125 ? -20.683 -18.754 6.846   1   22.25  ? 121 HIS A CB  1 
ATOM   994  C  CG  . HIS A 1 125 ? -21.918 -19.45  7.305   1   26.46  ? 121 HIS A CG  1 
ATOM   995  N  ND1 . HIS A 1 125 ? -22.069 -20.819 7.227   1   27.36  ? 121 HIS A ND1 1 
ATOM   996  C  CD2 . HIS A 1 125 ? -23.104 -18.975 7.723   1   27.48  ? 121 HIS A CD2 1 
ATOM   997  C  CE1 . HIS A 1 125 ? -23.287 -21.144 7.637   1   27.05  ? 121 HIS A CE1 1 
ATOM   998  N  NE2 . HIS A 1 125 ? -23.933 -20.043 7.927   1   25.57  ? 121 HIS A NE2 1 
ATOM   999  N  N   . ARG A 1 126 ? -18.974 -18.284 3.627   1   22.32  ? 122 ARG A N   1 
ATOM   1000 C  CA  . ARG A 1 126 ? -17.961 -17.605 2.831   1   22.01  ? 122 ARG A CA  1 
ATOM   1001 C  C   . ARG A 1 126 ? -16.75  -17.213 3.681   1   23.67  ? 122 ARG A C   1 
ATOM   1002 O  O   . ARG A 1 126 ? -16.205 -16.129 3.503   1   23.97  ? 122 ARG A O   1 
ATOM   1003 C  CB  . ARG A 1 126 ? -18.571 -16.507 1.945   1   19.85  ? 122 ARG A CB  1 
ATOM   1004 C  CG  . ARG A 1 126 ? -19.35  -15.442 2.718   1   20.15  ? 122 ARG A CG  1 
ATOM   1005 C  CD  . ARG A 1 126 ? -18.498 -14.361 3.333   1   20.43  ? 122 ARG A CD  1 
ATOM   1006 N  NE  . ARG A 1 126 ? -19.238 -13.29  4.005   1   25.61  ? 122 ARG A NE  1 
ATOM   1007 C  CZ  . ARG A 1 126 ? -19.702 -13.277 5.278   1   27.42  ? 122 ARG A CZ  1 
ATOM   1008 N  NH1 . ARG A 1 126 ? -19.572 -14.341 6.081   1   25.81  ? 122 ARG A NH1 1 
ATOM   1009 N  NH2 . ARG A 1 126 ? -20.296 -12.178 5.73    1   23.61  ? 122 ARG A NH2 1 
ATOM   1010 N  N   . VAL A 1 127 ? -16.281 -18.12  4.55    1   25.98  ? 123 VAL A N   1 
ATOM   1011 C  CA  . VAL A 1 127 ? -15.045 -17.911 5.301   1   26.25  ? 123 VAL A CA  1 
ATOM   1012 C  C   . VAL A 1 127 ? -14.03  -19.013 4.973   1   27.76  ? 123 VAL A C   1 
ATOM   1013 O  O   . VAL A 1 127 ? -14.339 -20.194 5.061   1   32.18  ? 123 VAL A O   1 
ATOM   1014 C  CB  . VAL A 1 127 ? -15.362 -17.864 6.807   1   23.99  ? 123 VAL A CB  1 
ATOM   1015 C  CG1 . VAL A 1 127 ? -14.107 -17.939 7.677   1   24.14  ? 123 VAL A CG1 1 
ATOM   1016 C  CG2 . VAL A 1 127 ? -16.203 -16.647 7.159   1   21.87  ? 123 VAL A CG2 1 
ATOM   1017 N  N   . LEU A 1 128 ? -12.815 -18.621 4.585   1   25.48  ? 124 LEU A N   1 
ATOM   1018 C  CA  . LEU A 1 128 ? -11.671 -19.513 4.526   1   24.19  ? 124 LEU A CA  1 
ATOM   1019 C  C   . LEU A 1 128 ? -10.943 -19.447 5.865   1   25.15  ? 124 LEU A C   1 
ATOM   1020 O  O   . LEU A 1 128 ? -10.729 -18.363 6.406   1   28.6   ? 124 LEU A O   1 
ATOM   1021 C  CB  . LEU A 1 128 ? -10.713 -19.069 3.423   1   22.62  ? 124 LEU A CB  1 
ATOM   1022 C  CG  . LEU A 1 128 ? -11.212 -19.102 1.98    1   24.35  ? 124 LEU A CG  1 
ATOM   1023 C  CD1 . LEU A 1 128 ? -10.112 -18.589 1.073   1   23.11  ? 124 LEU A CD1 1 
ATOM   1024 C  CD2 . LEU A 1 128 ? -11.555 -20.517 1.564   1   22.68  ? 124 LEU A CD2 1 
ATOM   1025 N  N   . HIS A 1 129 ? -10.478 -20.596 6.348   1   24.78  ? 125 HIS A N   1 
ATOM   1026 C  CA  . HIS A 1 129 ? -9.79   -20.63  7.617   1   25.81  ? 125 HIS A CA  1 
ATOM   1027 C  C   . HIS A 1 129 ? -8.333  -20.266 7.379   1   27.34  ? 125 HIS A C   1 
ATOM   1028 O  O   . HIS A 1 129 ? -7.854  -19.299 7.963   1   28.67  ? 125 HIS A O   1 
ATOM   1029 C  CB  . HIS A 1 129 ? -9.983  -21.971 8.325   1   24.86  ? 125 HIS A CB  1 
ATOM   1030 C  CG  . HIS A 1 129 ? -9.374  -21.971 9.686   1   25.96  ? 125 HIS A CG  1 
ATOM   1031 N  ND1 . HIS A 1 129 ? -8.01   -21.947 9.824   1   29.02  ? 125 HIS A ND1 1 
ATOM   1032 C  CD2 . HIS A 1 129 ? -9.86   -21.949 10.944  1   26.32  ? 125 HIS A CD2 1 
ATOM   1033 C  CE1 . HIS A 1 129 ? -7.691  -21.942 11.126  1   29.13  ? 125 HIS A CE1 1 
ATOM   1034 N  NE2 . HIS A 1 129 ? -8.795  -21.935 11.828  1   24.94  ? 125 HIS A NE2 1 
ATOM   1035 N  N   . ARG A 1 130 ? -7.648  -21.06  6.535   1   27.16  ? 126 ARG A N   1 
ATOM   1036 C  CA  . ARG A 1 130 ? -6.345  -20.71  5.986   1   25.46  ? 126 ARG A CA  1 
ATOM   1037 C  C   . ARG A 1 130 ? -5.242  -20.95  7.014   1   26.9   ? 126 ARG A C   1 
ATOM   1038 O  O   . ARG A 1 130 ? -4.14   -20.436 6.841   1   29.99  ? 126 ARG A O   1 
ATOM   1039 C  CB  . ARG A 1 130 ? -6.232  -19.253 5.502   1   21.84  ? 126 ARG A CB  1 
ATOM   1040 C  CG  . ARG A 1 130 ? -7.205  -18.942 4.371   1   21.38  ? 126 ARG A CG  1 
ATOM   1041 C  CD  . ARG A 1 130 ? -6.904  -17.666 3.613   1   21.03  ? 126 ARG A CD  1 
ATOM   1042 N  NE  . ARG A 1 130 ? -6.81   -16.558 4.564   1   19.74  ? 126 ARG A NE  1 
ATOM   1043 C  CZ  . ARG A 1 130 ? -6.401  -15.339 4.274   1   19.46  ? 126 ARG A CZ  1 
ATOM   1044 N  NH1 . ARG A 1 130 ? -5.986  -15.024 3.063   1   16.73  ? 126 ARG A NH1 1 
ATOM   1045 N  NH2 . ARG A 1 130 ? -6.394  -14.427 5.229   1   20.18  ? 126 ARG A NH2 1 
ATOM   1046 N  N   . ASP A 1 131 ? -5.512  -21.739 8.063   1   25.04  ? 127 ASP A N   1 
ATOM   1047 C  CA  . ASP A 1 131 ? -4.44   -22.147 8.961   1   26.39  ? 127 ASP A CA  1 
ATOM   1048 C  C   . ASP A 1 131 ? -4.878  -23.39  9.729   1   27.96  ? 127 ASP A C   1 
ATOM   1049 O  O   . ASP A 1 131 ? -4.657  -23.496 10.943  1   31.1   ? 127 ASP A O   1 
ATOM   1050 C  CB  . ASP A 1 131 ? -4.013  -21.011 9.874   1   26.88  ? 127 ASP A CB  1 
ATOM   1051 C  CG  . ASP A 1 131 ? -2.669  -21.143 10.571  1   31.02  ? 127 ASP A CG  1 
ATOM   1052 O  OD1 . ASP A 1 131 ? -1.711  -21.681 9.975   1   31.88  ? 127 ASP A OD1 1 
ATOM   1053 O  OD2 . ASP A 1 131 ? -2.575  -20.626 11.692  1   39.75  ? 127 ASP A OD2 1 
ATOM   1054 N  N   . LEU A 1 132 ? -5.486  -24.338 9.008   1   23.26  ? 128 LEU A N   1 
ATOM   1055 C  CA  . LEU A 1 132 ? -5.861  -25.571 9.664   1   24.92  ? 128 LEU A CA  1 
ATOM   1056 C  C   . LEU A 1 132 ? -4.609  -26.405 9.934   1   27.34  ? 128 LEU A C   1 
ATOM   1057 O  O   . LEU A 1 132 ? -3.782  -26.673 9.049   1   28.72  ? 128 LEU A O   1 
ATOM   1058 C  CB  . LEU A 1 132 ? -6.885  -26.267 8.783   1   26.74  ? 128 LEU A CB  1 
ATOM   1059 C  CG  . LEU A 1 132 ? -8.197  -25.5   8.685   1   26.16  ? 128 LEU A CG  1 
ATOM   1060 C  CD1 . LEU A 1 132 ? -9.11   -26.182 7.671   1   25.06  ? 128 LEU A CD1 1 
ATOM   1061 C  CD2 . LEU A 1 132 ? -8.795  -25.386 10.077  1   22.45  ? 128 LEU A CD2 1 
ATOM   1062 N  N   . LYS A 1 133 ? -4.435  -26.713 11.212  1   23.18  ? 129 LYS A N   1 
ATOM   1063 C  CA  . LYS A 1 133 ? -3.327  -27.523 11.662  1   24.36  ? 129 LYS A CA  1 
ATOM   1064 C  C   . LYS A 1 133 ? -3.679  -27.98  13.066  1   27.12  ? 129 LYS A C   1 
ATOM   1065 O  O   . LYS A 1 133 ? -4.553  -27.408 13.709  1   29.11  ? 129 LYS A O   1 
ATOM   1066 C  CB  . LYS A 1 133 ? -2.004  -26.756 11.621  1   24.1   ? 129 LYS A CB  1 
ATOM   1067 C  CG  . LYS A 1 133 ? -2.049  -25.489 12.424  1   25.33  ? 129 LYS A CG  1 
ATOM   1068 C  CD  . LYS A 1 133 ? -0.677  -24.863 12.563  1   27.17  ? 129 LYS A CD  1 
ATOM   1069 C  CE  . LYS A 1 133 ? -0.72   -23.537 13.283  1   29.41  ? 129 LYS A CE  1 
ATOM   1070 N  NZ  . LYS A 1 133 ? 0.556   -22.812 13.11   1   31.67  ? 129 LYS A NZ  1 
ATOM   1071 N  N   . PRO A 1 134 ? -3.082  -29.076 13.562  1   27.52  ? 130 PRO A N   1 
ATOM   1072 C  CA  . PRO A 1 134 ? -3.562  -29.679 14.809  1   27     ? 130 PRO A CA  1 
ATOM   1073 C  C   . PRO A 1 134 ? -3.531  -28.774 16.039  1   31.8   ? 130 PRO A C   1 
ATOM   1074 O  O   . PRO A 1 134 ? -4.366  -28.916 16.933  1   33.8   ? 130 PRO A O   1 
ATOM   1075 C  CB  . PRO A 1 134 ? -2.64   -30.862 14.919  1   24.35  ? 130 PRO A CB  1 
ATOM   1076 C  CG  . PRO A 1 134 ? -2.352  -31.176 13.476  1   23.79  ? 130 PRO A CG  1 
ATOM   1077 C  CD  . PRO A 1 134 ? -2.015  -29.829 12.886  1   24.29  ? 130 PRO A CD  1 
ATOM   1078 N  N   . GLN A 1 135 ? -2.578  -27.835 16.054  1   33.16  ? 131 GLN A N   1 
ATOM   1079 C  CA  . GLN A 1 135 ? -2.429  -26.844 17.11   1   30.57  ? 131 GLN A CA  1 
ATOM   1080 C  C   . GLN A 1 135 ? -3.674  -25.956 17.149  1   31.31  ? 131 GLN A C   1 
ATOM   1081 O  O   . GLN A 1 135 ? -3.954  -25.318 18.163  1   32.46  ? 131 GLN A O   1 
ATOM   1082 C  CB  . GLN A 1 135 ? -1.199  -25.959 16.878  1   30.38  ? 131 GLN A CB  1 
ATOM   1083 C  CG  . GLN A 1 135 ? 0.155   -26.669 16.83   1   37.82  ? 131 GLN A CG  1 
ATOM   1084 C  CD  . GLN A 1 135 ? 0.5     -27.487 15.58   1   47.71  ? 131 GLN A CD  1 
ATOM   1085 O  OE1 . GLN A 1 135 ? -0.224  -27.584 14.574  1   38.62  ? 131 GLN A OE1 1 
ATOM   1086 N  NE2 . GLN A 1 135 ? 1.662   -28.126 15.637  1   51.26  ? 131 GLN A NE2 1 
ATOM   1087 N  N   . ASN A 1 136 ? -4.403  -25.875 16.026  1   29.43  ? 132 ASN A N   1 
ATOM   1088 C  CA  . ASN A 1 136 ? -5.524  -24.948 15.894  1   27.44  ? 132 ASN A CA  1 
ATOM   1089 C  C   . ASN A 1 136 ? -6.844  -25.712 15.959  1   27.48  ? 132 ASN A C   1 
ATOM   1090 O  O   . ASN A 1 136 ? -7.89   -25.172 15.609  1   26.96  ? 132 ASN A O   1 
ATOM   1091 C  CB  . ASN A 1 136 ? -5.441  -24.122 14.613  1   25.2   ? 132 ASN A CB  1 
ATOM   1092 C  CG  . ASN A 1 136 ? -4.428  -23.007 14.689  1   25.41  ? 132 ASN A CG  1 
ATOM   1093 O  OD1 . ASN A 1 136 ? -3.947  -22.651 15.767  1   26.25  ? 132 ASN A OD1 1 
ATOM   1094 N  ND2 . ASN A 1 136 ? -4.054  -22.455 13.549  1   24.44  ? 132 ASN A ND2 1 
ATOM   1095 N  N   . LEU A 1 137 ? -6.795  -26.964 16.435  1   24.21  ? 133 LEU A N   1 
ATOM   1096 C  CA  . LEU A 1 137 ? -8.012  -27.732 16.586  1   23.39  ? 133 LEU A CA  1 
ATOM   1097 C  C   . LEU A 1 137 ? -8.14   -28.162 18.039  1   27.52  ? 133 LEU A C   1 
ATOM   1098 O  O   . LEU A 1 137 ? -7.268  -28.859 18.566  1   32.18  ? 133 LEU A O   1 
ATOM   1099 C  CB  . LEU A 1 137 ? -7.926  -28.913 15.631  1   22.79  ? 133 LEU A CB  1 
ATOM   1100 C  CG  . LEU A 1 137 ? -7.564  -28.585 14.174  1   21.5   ? 133 LEU A CG  1 
ATOM   1101 C  CD1 . LEU A 1 137 ? -7.564  -29.9   13.345  1   21.84  ? 133 LEU A CD1 1 
ATOM   1102 C  CD2 . LEU A 1 137 ? -8.538  -27.566 13.583  1   18.35  ? 133 LEU A CD2 1 
ATOM   1103 N  N   . LEU A 1 138 ? -9.213  -27.697 18.693  1   26.08  ? 134 LEU A N   1 
ATOM   1104 C  CA  . LEU A 1 138 ? -9.346  -27.898 20.125  1   24.81  ? 134 LEU A CA  1 
ATOM   1105 C  C   . LEU A 1 138 ? -10.278 -29.07  20.424  1   23.88  ? 134 LEU A C   1 
ATOM   1106 O  O   . LEU A 1 138 ? -11.25  -29.286 19.715  1   24.32  ? 134 LEU A O   1 
ATOM   1107 C  CB  . LEU A 1 138 ? -9.841  -26.563 20.672  1   24.83  ? 134 LEU A CB  1 
ATOM   1108 C  CG  . LEU A 1 138 ? -8.893  -25.372 20.456  1   26.73  ? 134 LEU A CG  1 
ATOM   1109 C  CD1 . LEU A 1 138 ? -9.351  -24.174 21.246  1   22.26  ? 134 LEU A CD1 1 
ATOM   1110 C  CD2 . LEU A 1 138 ? -7.421  -25.649 20.763  1   24.44  ? 134 LEU A CD2 1 
ATOM   1111 N  N   . ILE A 1 139 ? -9.963  -29.826 21.476  1   22.06  ? 135 ILE A N   1 
ATOM   1112 C  CA  . ILE A 1 139 ? -10.732 -30.997 21.862  1   21.53  ? 135 ILE A CA  1 
ATOM   1113 C  C   . ILE A 1 139 ? -11.195 -30.776 23.29   1   22.39  ? 135 ILE A C   1 
ATOM   1114 O  O   . ILE A 1 139 ? -10.469 -30.225 24.115  1   25.95  ? 135 ILE A O   1 
ATOM   1115 C  CB  . ILE A 1 139 ? -9.907  -32.3   21.746  1   23.56  ? 135 ILE A CB  1 
ATOM   1116 C  CG1 . ILE A 1 139 ? -8.671  -32.302 22.647  1   25.61  ? 135 ILE A CG1 1 
ATOM   1117 C  CG2 . ILE A 1 139 ? -9.503  -32.618 20.305  1   21.7   ? 135 ILE A CG2 1 
ATOM   1118 C  CD1 . ILE A 1 139 ? -7.909  -33.618 22.655  1   25.6   ? 135 ILE A CD1 1 
ATOM   1119 N  N   . ASN A 1 140 ? -12.413 -31.21  23.584  1   23.26  ? 136 ASN A N   1 
ATOM   1120 C  CA  . ASN A 1 140 ? -12.932 -31.117 24.938  1   25.62  ? 136 ASN A CA  1 
ATOM   1121 C  C   . ASN A 1 140 ? -12.872 -32.51  25.559  1   28.11  ? 136 ASN A C   1 
ATOM   1122 O  O   . ASN A 1 140 ? -12.309 -33.427 24.961  1   28.79  ? 136 ASN A O   1 
ATOM   1123 C  CB  . ASN A 1 140 ? -14.301 -30.437 24.988  1   25.77  ? 136 ASN A CB  1 
ATOM   1124 C  CG  . ASN A 1 140 ? -15.423 -31.222 24.339  1   28.06  ? 136 ASN A CG  1 
ATOM   1125 O  OD1 . ASN A 1 140 ? -15.353 -32.444 24.135  1   26.41  ? 136 ASN A OD1 1 
ATOM   1126 N  ND2 . ASN A 1 140 ? -16.498 -30.52  24.02   1   28.34  ? 136 ASN A ND2 1 
ATOM   1127 N  N   . THR A 1 141 ? -13.457 -32.647 26.756  1   29.53  ? 137 THR A N   1 
ATOM   1128 C  CA  . THR A 1 141 ? -13.437 -33.904 27.498  1   28.14  ? 137 THR A CA  1 
ATOM   1129 C  C   . THR A 1 141 ? -14.555 -34.833 27.027  1   29.13  ? 137 THR A C   1 
ATOM   1130 O  O   . THR A 1 141 ? -14.569 -35.986 27.427  1   31.54  ? 137 THR A O   1 
ATOM   1131 C  CB  . THR A 1 141 ? -13.602 -33.654 28.998  1   24.88  ? 137 THR A CB  1 
ATOM   1132 O  OG1 . THR A 1 141 ? -14.505 -32.56  29.068  1   25     ? 137 THR A OG1 1 
ATOM   1133 C  CG2 . THR A 1 141 ? -12.323 -33.234 29.694  1   24.49  ? 137 THR A CG2 1 
ATOM   1134 N  N   . GLU A 1 142 ? -15.509 -34.314 26.241  1   29.6   ? 138 GLU A N   1 
ATOM   1135 C  CA  . GLU A 1 142 ? -16.699 -35.04  25.819  1   33.38  ? 138 GLU A CA  1 
ATOM   1136 C  C   . GLU A 1 142 ? -16.522 -35.652 24.423  1   32.4   ? 138 GLU A C   1 
ATOM   1137 O  O   . GLU A 1 142 ? -17.448 -36.258 23.887  1   36.58  ? 138 GLU A O   1 
ATOM   1138 C  CB  . GLU A 1 142 ? -17.891 -34.084 25.685  1   38.19  ? 138 GLU A CB  1 
ATOM   1139 C  CG  . GLU A 1 142 ? -18.25  -33.319 26.953  1   39.15  ? 138 GLU A CG  1 
ATOM   1140 C  CD  . GLU A 1 142 ? -19.098 -34.165 27.867  1   47.93  ? 138 GLU A CD  1 
ATOM   1141 O  OE1 . GLU A 1 142 ? -20.092 -34.777 27.405  1   50.21  ? 138 GLU A OE1 1 
ATOM   1142 O  OE2 . GLU A 1 142 ? -18.765 -34.177 29.067  1   56.06  ? 138 GLU A OE2 1 
ATOM   1143 N  N   . GLY A 1 143 ? -15.372 -35.446 23.784  1   27.87  ? 139 GLY A N   1 
ATOM   1144 C  CA  . GLY A 1 143 ? -15.199 -36.035 22.467  1   26.53  ? 139 GLY A CA  1 
ATOM   1145 C  C   . GLY A 1 143 ? -15.412 -35.07  21.296  1   24.92  ? 139 GLY A C   1 
ATOM   1146 O  O   . GLY A 1 143 ? -15.321 -35.5   20.136  1   23.73  ? 139 GLY A O   1 
ATOM   1147 N  N   . ALA A 1 144 ? -15.665 -33.779 21.581  1   22     ? 140 ALA A N   1 
ATOM   1148 C  CA  . ALA A 1 144 ? -15.875 -32.816 20.51   1   21.74  ? 140 ALA A CA  1 
ATOM   1149 C  C   . ALA A 1 144 ? -14.542 -32.229 20.06   1   24.42  ? 140 ALA A C   1 
ATOM   1150 O  O   . ALA A 1 144 ? -13.649 -32.056 20.871  1   29.38  ? 140 ALA A O   1 
ATOM   1151 C  CB  . ALA A 1 144 ? -16.798 -31.733 20.974  1   20.01  ? 140 ALA A CB  1 
ATOM   1152 N  N   . ILE A 1 145 ? -14.401 -31.929 18.766  1   23.35  ? 141 ILE A N   1 
ATOM   1153 C  CA  . ILE A 1 145 ? -13.224 -31.234 18.278  1   22.96  ? 141 ILE A CA  1 
ATOM   1154 C  C   . ILE A 1 145 ? -13.721 -30.028 17.486  1   25.4   ? 141 ILE A C   1 
ATOM   1155 O  O   . ILE A 1 145 ? -14.721 -30.12  16.782  1   23.54  ? 141 ILE A O   1 
ATOM   1156 C  CB  . ILE A 1 145 ? -12.295 -32.144 17.449  1   23.73  ? 141 ILE A CB  1 
ATOM   1157 C  CG1 . ILE A 1 145 ? -10.974 -31.449 17.095  1   24.93  ? 141 ILE A CG1 1 
ATOM   1158 C  CG2 . ILE A 1 145 ? -12.988 -32.646 16.181  1   25.13  ? 141 ILE A CG2 1 
ATOM   1159 C  CD1 . ILE A 1 145 ? -9.977  -32.33  16.378  1   21.92  ? 141 ILE A CD1 1 
ATOM   1160 N  N   . LYS A 1 146 ? -13.024 -28.885 17.614  1   26.94  ? 142 LYS A N   1 
ATOM   1161 C  CA  . LYS A 1 146 ? -13.579 -27.648 17.089  1   24.46  ? 142 LYS A CA  1 
ATOM   1162 C  C   . LYS A 1 146 ? -12.476 -26.838 16.434  1   25.76  ? 142 LYS A C   1 
ATOM   1163 O  O   . LYS A 1 146 ? -11.396 -26.734 17.004  1   29.43  ? 142 LYS A O   1 
ATOM   1164 C  CB  . LYS A 1 146 ? -14.233 -26.822 18.194  1   21.93  ? 142 LYS A CB  1 
ATOM   1165 C  CG  . LYS A 1 146 ? -15.153 -27.613 19.102  1   24.2   ? 142 LYS A CG  1 
ATOM   1166 C  CD  . LYS A 1 146 ? -16.091 -26.749 19.938  1   23.26  ? 142 LYS A CD  1 
ATOM   1167 C  CE  . LYS A 1 146 ? -17.018 -27.579 20.768  1   22.01  ? 142 LYS A CE  1 
ATOM   1168 N  NZ  . LYS A 1 146 ? -18.279 -26.857 20.987  1   25.73  ? 142 LYS A NZ  1 
ATOM   1169 N  N   . LEU A 1 147 ? -12.783 -26.263 15.258  1   23.54  ? 143 LEU A N   1 
ATOM   1170 C  CA  . LEU A 1 147 ? -11.876 -25.36  14.563  1   23.59  ? 143 LEU A CA  1 
ATOM   1171 C  C   . LEU A 1 147 ? -11.646 -24.133 15.44   1   24.14  ? 143 LEU A C   1 
ATOM   1172 O  O   . LEU A 1 147 ? -12.596 -23.584 16.001  1   23.74  ? 143 LEU A O   1 
ATOM   1173 C  CB  . LEU A 1 147 ? -12.389 -24.923 13.192  1   23.51  ? 143 LEU A CB  1 
ATOM   1174 C  CG  . LEU A 1 147 ? -12.976 -25.982 12.246  1   26.06  ? 143 LEU A CG  1 
ATOM   1175 C  CD1 . LEU A 1 147 ? -13.053 -25.344 10.872  1   29     ? 143 LEU A CD1 1 
ATOM   1176 C  CD2 . LEU A 1 147 ? -12.186 -27.249 12.153  1   23.19  ? 143 LEU A CD2 1 
ATOM   1177 N  N   . ALA A 1 148 ? -10.386 -23.689 15.521  1   23.23  ? 144 ALA A N   1 
ATOM   1178 C  CA  . ALA A 1 148 ? -10.061 -22.526 16.333  1   25.69  ? 144 ALA A CA  1 
ATOM   1179 C  C   . ALA A 1 148 ? -9.004  -21.689 15.623  1   25.61  ? 144 ALA A C   1 
ATOM   1180 O  O   . ALA A 1 148 ? -8.489  -22.103 14.579  1   26.92  ? 144 ALA A O   1 
ATOM   1181 C  CB  . ALA A 1 148 ? -9.651  -22.93  17.751  1   23.04  ? 144 ALA A CB  1 
ATOM   1182 N  N   . ASP A 1 149 ? -8.726  -20.517 16.211  1   25.92  ? 145 ASP A N   1 
ATOM   1183 C  CA  . ASP A 1 149 ? -7.796  -19.506 15.737  1   29.73  ? 145 ASP A CA  1 
ATOM   1184 C  C   . ASP A 1 149 ? -8.164  -19.029 14.323  1   27     ? 145 ASP A C   1 
ATOM   1185 O  O   . ASP A 1 149 ? -7.668  -19.559 13.327  1   25.8   ? 145 ASP A O   1 
ATOM   1186 C  CB  . ASP A 1 149 ? -6.344  -19.932 15.92   1   32.97  ? 145 ASP A CB  1 
ATOM   1187 C  CG  . ASP A 1 149 ? -5.341  -18.795 15.737  1   40.85  ? 145 ASP A CG  1 
ATOM   1188 O  OD1 . ASP A 1 149 ? -5.762  -17.659 15.381  1   37.51  ? 145 ASP A OD1 1 
ATOM   1189 O  OD2 . ASP A 1 149 ? -4.139  -19.037 15.972  1   49.32  ? 145 ASP A OD2 1 
ATOM   1190 N  N   . PHE A 1 150 ? -8.992  -17.986 14.255  1   22.04  ? 146 PHE A N   1 
ATOM   1191 C  CA  . PHE A 1 150 ? -9.477  -17.471 12.985  1   23.6   ? 146 PHE A CA  1 
ATOM   1192 C  C   . PHE A 1 150 ? -8.74   -16.187 12.621  1   24.3   ? 146 PHE A C   1 
ATOM   1193 O  O   . PHE A 1 150 ? -9.26   -15.371 11.868  1   24.08  ? 146 PHE A O   1 
ATOM   1194 C  CB  . PHE A 1 150 ? -10.992 -17.241 13.048  1   22.92  ? 146 PHE A CB  1 
ATOM   1195 C  CG  . PHE A 1 150 ? -11.786 -18.503 12.769  1   22.02  ? 146 PHE A CG  1 
ATOM   1196 C  CD1 . PHE A 1 150 ? -11.858 -19.52  13.718  1   19.83  ? 146 PHE A CD1 1 
ATOM   1197 C  CD2 . PHE A 1 150 ? -12.435 -18.673 11.547  1   21.49  ? 146 PHE A CD2 1 
ATOM   1198 C  CE1 . PHE A 1 150 ? -12.549 -20.686 13.447  1   20.17  ? 146 PHE A CE1 1 
ATOM   1199 C  CE2 . PHE A 1 150 ? -13.155 -19.833 11.291  1   19.59  ? 146 PHE A CE2 1 
ATOM   1200 C  CZ  . PHE A 1 150 ? -13.196 -20.845 12.231  1   20.74  ? 146 PHE A CZ  1 
ATOM   1201 N  N   . GLY A 1 151 ? -7.528  -16.027 13.168  1   27.42  ? 147 GLY A N   1 
ATOM   1202 C  CA  . GLY A 1 151 ? -6.686  -14.851 12.971  1   26.79  ? 147 GLY A CA  1 
ATOM   1203 C  C   . GLY A 1 151 ? -6.193  -14.749 11.534  1   26.83  ? 147 GLY A C   1 
ATOM   1204 O  O   . GLY A 1 151 ? -6.089  -13.656 10.998  1   30.28  ? 147 GLY A O   1 
ATOM   1205 N  N   . LEU A 1 152 ? -5.979  -15.892 10.884  1   27.64  ? 148 LEU A N   1 
ATOM   1206 C  CA  . LEU A 1 152 ? -5.608  -15.862 9.478   1   30.47  ? 148 LEU A CA  1 
ATOM   1207 C  C   . LEU A 1 152 ? -6.807  -16.012 8.542   1   28.15  ? 148 LEU A C   1 
ATOM   1208 O  O   . LEU A 1 152 ? -6.613  -16.075 7.328   1   29.63  ? 148 LEU A O   1 
ATOM   1209 C  CB  . LEU A 1 152 ? -4.479  -16.835 9.173   1   31.68  ? 148 LEU A CB  1 
ATOM   1210 C  CG  . LEU A 1 152 ? -3.238  -16.519 10.008  1   45.25  ? 148 LEU A CG  1 
ATOM   1211 C  CD1 . LEU A 1 152 ? -3.031  -17.548 11.145  1   50.35  ? 148 LEU A CD1 1 
ATOM   1212 C  CD2 . LEU A 1 152 ? -1.978  -16.233 9.192   1   48.52  ? 148 LEU A CD2 1 
ATOM   1213 N  N   . ALA A 1 153 ? -8.028  -15.966 9.093   1   25.34  ? 149 ALA A N   1 
ATOM   1214 C  CA  . ALA A 1 153 ? -9.234  -16.263 8.334   1   25.85  ? 149 ALA A CA  1 
ATOM   1215 C  C   . ALA A 1 153 ? -9.555  -15.098 7.387   1   27.11  ? 149 ALA A C   1 
ATOM   1216 O  O   . ALA A 1 153 ? -8.975  -14.02  7.531   1   27.18  ? 149 ALA A O   1 
ATOM   1217 C  CB  . ALA A 1 153 ? -10.346 -16.615 9.296   1   23.02  ? 149 ALA A CB  1 
ATOM   1218 N  N   . ARG A 1 154 ? -10.392 -15.37  6.383   1   26.59  ? 150 ARG A N   1 
ATOM   1219 C  CA  . ARG A 1 154 ? -10.754 -14.338 5.379   1   28.31  ? 150 ARG A CA  1 
ATOM   1220 C  C   . ARG A 1 154 ? -12.168 -14.507 4.822   1   27.07  ? 150 ARG A C   1 
ATOM   1221 O  O   . ARG A 1 154 ? -12.498 -15.614 4.383   1   28.09  ? 150 ARG A O   1 
ATOM   1222 C  CB  . ARG A 1 154 ? -9.896  -14.427 4.116   1   30.73  ? 150 ARG A CB  1 
ATOM   1223 C  CG  . ARG A 1 154 ? -10.095 -13.354 3.058   1   30.54  ? 150 ARG A CG  1 
ATOM   1224 C  CD  . ARG A 1 154 ? -9.234  -12.151 3.363   1   33.48  ? 150 ARG A CD  1 
ATOM   1225 N  NE  . ARG A 1 154 ? -8.592  -11.63  2.154   1   33.15  ? 150 ARG A NE  1 
ATOM   1226 C  CZ  . ARG A 1 154 ? -8.687  -10.377 1.749   1   29.49  ? 150 ARG A CZ  1 
ATOM   1227 N  NH1 . ARG A 1 154 ? -7.609  -9.719  1.377   1   29.09  ? 150 ARG A NH1 1 
ATOM   1228 N  NH2 . ARG A 1 154 ? -9.863  -9.786  1.721   1   28.7   ? 150 ARG A NH2 1 
ATOM   1229 N  N   . ALA A 1 155 ? -12.974 -13.441 4.85    1   25.92  ? 151 ALA A N   1 
ATOM   1230 C  CA  . ALA A 1 155 ? -14.253 -13.509 4.151   1   24.1   ? 151 ALA A CA  1 
ATOM   1231 C  C   . ALA A 1 155 ? -14.053 -13.404 2.639   1   24.39  ? 151 ALA A C   1 
ATOM   1232 O  O   . ALA A 1 155 ? -13.587 -12.379 2.162   1   27.36  ? 151 ALA A O   1 
ATOM   1233 C  CB  . ALA A 1 155 ? -15.172 -12.441 4.637   1   19.65  ? 151 ALA A CB  1 
ATOM   1234 N  N   . PHE A 1 156 ? -14.461 -14.436 1.89    1   23.48  ? 152 PHE A N   1 
ATOM   1235 C  CA  . PHE A 1 156 ? -14.281 -14.428 0.446   1   24.66  ? 152 PHE A CA  1 
ATOM   1236 C  C   . PHE A 1 156 ? -15.564 -14.07  -0.298  1   25.67  ? 152 PHE A C   1 
ATOM   1237 O  O   . PHE A 1 156 ? -16.671 -14.069 0.261   1   28.87  ? 152 PHE A O   1 
ATOM   1238 C  CB  . PHE A 1 156 ? -13.698 -15.711 -0.132  1   21.85  ? 152 PHE A CB  1 
ATOM   1239 C  CG  . PHE A 1 156 ? -14.526 -16.974 0.02    1   22.65  ? 152 PHE A CG  1 
ATOM   1240 C  CD1 . PHE A 1 156 ? -14.438 -17.747 1.177   1   21.29  ? 152 PHE A CD1 1 
ATOM   1241 C  CD2 . PHE A 1 156 ? -15.349 -17.423 -1.017  1   23.49  ? 152 PHE A CD2 1 
ATOM   1242 C  CE1 . PHE A 1 156 ? -15.173 -18.919 1.307   1   20.39  ? 152 PHE A CE1 1 
ATOM   1243 C  CE2 . PHE A 1 156 ? -16.072 -18.611 -0.89   1   22.72  ? 152 PHE A CE2 1 
ATOM   1244 C  CZ  . PHE A 1 156 ? -15.98  -19.361 0.269   1   20.25  ? 152 PHE A CZ  1 
ATOM   1245 N  N   . GLY A 1 157 ? -15.365 -13.714 -1.571  1   22.44  ? 153 GLY A N   1 
ATOM   1246 C  CA  . GLY A 1 157 ? -16.438 -13.423 -2.51   1   19.04  ? 153 GLY A CA  1 
ATOM   1247 C  C   . GLY A 1 157 ? -16.465 -14.493 -3.604  1   18.69  ? 153 GLY A C   1 
ATOM   1248 O  O   . GLY A 1 157 ? -15.512 -15.287 -3.757  1   15.76  ? 153 GLY A O   1 
ATOM   1249 N  N   . VAL A 1 158 ? -17.567 -14.492 -4.365  1   17.68  ? 154 VAL A N   1 
ATOM   1250 C  CA  . VAL A 1 158 ? -17.739 -15.518 -5.37   1   18.21  ? 154 VAL A CA  1 
ATOM   1251 C  C   . VAL A 1 158 ? -17.872 -14.848 -6.733  1   18.61  ? 154 VAL A C   1 
ATOM   1252 O  O   . VAL A 1 158 ? -18.743 -13.984 -6.91   1   17.1   ? 154 VAL A O   1 
ATOM   1253 C  CB  . VAL A 1 158 ? -18.954 -16.396 -5.042  1   20.24  ? 154 VAL A CB  1 
ATOM   1254 C  CG1 . VAL A 1 158 ? -19     -17.569 -6.009  1   22.43  ? 154 VAL A CG1 1 
ATOM   1255 C  CG2 . VAL A 1 158 ? -18.915 -16.91  -3.603  1   19.71  ? 154 VAL A CG2 1 
ATOM   1256 N  N   . PRO A 1 159 ? -16.951 -15.141 -7.696  1   18.72  ? 155 PRO A N   1 
ATOM   1257 C  CA  . PRO A 1 159 ? -15.726 -15.923 -7.441  1   19.05  ? 155 PRO A CA  1 
ATOM   1258 C  C   . PRO A 1 159 ? -14.687 -15.208 -6.588  1   21.35  ? 155 PRO A C   1 
ATOM   1259 O  O   . PRO A 1 159 ? -14.745 -13.981 -6.458  1   24.64  ? 155 PRO A O   1 
ATOM   1260 C  CB  . PRO A 1 159 ? -15.139 -16.182 -8.833  1   16.95  ? 155 PRO A CB  1 
ATOM   1261 C  CG  . PRO A 1 159 ? -15.686 -15.067 -9.673  1   16.47  ? 155 PRO A CG  1 
ATOM   1262 C  CD  . PRO A 1 159 ? -17.046 -14.701 -9.099  1   17.2   ? 155 PRO A CD  1 
ATOM   1263 N  N   . VAL A 1 160 ? -13.721 -15.966 -6.057  1   20.39  ? 156 VAL A N   1 
ATOM   1264 C  CA  . VAL A 1 160 ? -12.686 -15.409 -5.196  1   21.77  ? 156 VAL A CA  1 
ATOM   1265 C  C   . VAL A 1 160 ? -11.82  -14.431 -5.999  1   23.3   ? 156 VAL A C   1 
ATOM   1266 O  O   . VAL A 1 160 ? -11.741 -14.51  -7.225  1   22     ? 156 VAL A O   1 
ATOM   1267 C  CB  . VAL A 1 160 ? -11.827 -16.535 -4.595  1   20.8   ? 156 VAL A CB  1 
ATOM   1268 C  CG1 . VAL A 1 160 ? -12.663 -17.498 -3.776  1   20.44  ? 156 VAL A CG1 1 
ATOM   1269 C  CG2 . VAL A 1 160 ? -11.097 -17.302 -5.694  1   21.33  ? 156 VAL A CG2 1 
ATOM   1270 N  N   . ARG A 1 161 ? -11.149 -13.534 -5.276  1   25.7   ? 157 ARG A N   1 
ATOM   1271 C  CA  . ARG A 1 161 ? -10.168 -12.643 -5.942  1   30.25  ? 157 ARG A CA  1 
ATOM   1272 C  C   . ARG A 1 161 ? -8.81   -12.97  -5.301  1   29.97  ? 157 ARG A C   1 
ATOM   1273 O  O   . ARG A 1 161 ? -8.776  -13.831 -4.394  1   30.05  ? 157 ARG A O   1 
ATOM   1274 C  CB  . ARG A 1 161 ? -10.542 -11.161 -5.819  1   31.23  ? 157 ARG A CB  1 
ATOM   1275 C  CG  . ARG A 1 161 ? -10.733 -10.655 -4.398  1   33.5   ? 157 ARG A CG  1 
ATOM   1276 C  CD  . ARG A 1 161 ? -9.73   -9.583  -4.004  1   42.1   ? 157 ARG A CD  1 
ATOM   1277 N  NE  . ARG A 1 161 ? -9.891  -9.195  -2.599  1   48.57  ? 157 ARG A NE  1 
ATOM   1278 C  CZ  . ARG A 1 161 ? -8.931  -8.692  -1.835  1   49.07  ? 157 ARG A CZ  1 
ATOM   1279 N  NH1 . ARG A 1 161 ? -9.154  -7.596  -1.134  1   49.97  ? 157 ARG A NH1 1 
ATOM   1280 N  NH2 . ARG A 1 161 ? -7.753  -9.284  -1.774  1   44.5   ? 157 ARG A NH2 1 
ATOM   1281 N  N   . THR A 1 162 ? -7.738  -12.326 -5.754  1   27.22  ? 158 THR A N   1 
ATOM   1282 C  CA  . THR A 1 162 ? -6.413  -12.609 -5.214  1   28.77  ? 158 THR A CA  1 
ATOM   1283 C  C   . THR A 1 162 ? -6.396  -12.219 -3.733  1   26.73  ? 158 THR A C   1 
ATOM   1284 O  O   . THR A 1 162 ? -6.718  -11.087 -3.388  1   24.21  ? 158 THR A O   1 
ATOM   1285 C  CB  . THR A 1 162 ? -5.303  -11.899 -5.998  1   31.32  ? 158 THR A CB  1 
ATOM   1286 O  OG1 . THR A 1 162 ? -5.318  -12.321 -7.363  1   40.83  ? 158 THR A OG1 1 
ATOM   1287 C  CG2 . THR A 1 162 ? -3.915  -12.222 -5.469  1   26.5   ? 158 THR A CG2 1 
ATOM   1288 N  N   . TYR A 1 163 ? -6.03   -13.168 -2.867  1   24.39  ? 159 TYR A N   1 
ATOM   1289 C  CA  . TYR A 1 163 ? -5.838  -12.833 -1.464  1   26.57  ? 159 TYR A CA  1 
ATOM   1290 C  C   . TYR A 1 163 ? -4.36   -12.98  -1.094  1   25.66  ? 159 TYR A C   1 
ATOM   1291 O  O   . TYR A 1 163 ? -3.49   -13.112 -1.949  1   27.37  ? 159 TYR A O   1 
ATOM   1292 C  CB  . TYR A 1 163 ? -6.772  -13.649 -0.559  1   28.67  ? 159 TYR A CB  1 
ATOM   1293 C  CG  . TYR A 1 163 ? -8.245  -13.644 -0.938  1   28.24  ? 159 TYR A CG  1 
ATOM   1294 C  CD1 . TYR A 1 163 ? -8.929  -12.453 -1.165  1   26.11  ? 159 TYR A CD1 1 
ATOM   1295 C  CD2 . TYR A 1 163 ? -8.934  -14.842 -1.096  1   26.31  ? 159 TYR A CD2 1 
ATOM   1296 C  CE1 . TYR A 1 163 ? -10.258 -12.461 -1.55   1   27.21  ? 159 TYR A CE1 1 
ATOM   1297 C  CE2 . TYR A 1 163 ? -10.269 -14.857 -1.476  1   26.88  ? 159 TYR A CE2 1 
ATOM   1298 C  CZ  . TYR A 1 163 ? -10.927 -13.664 -1.713  1   28.16  ? 159 TYR A CZ  1 
ATOM   1299 O  OH  . TYR A 1 163 ? -12.24  -13.695 -2.078  1   29.33  ? 159 TYR A OH  1 
HETATM 1300 N  N   . TPO A 1 164 ? -4.079  -12.933 0.202   1   25.19  ? 160 TPO A N   1 
HETATM 1301 C  CA  . TPO A 1 164 ? -2.719  -12.954 0.71    1   28     ? 160 TPO A CA  1 
HETATM 1302 C  CB  . TPO A 1 164 ? -2.749  -12.801 2.24    1   26.18  ? 160 TPO A CB  1 
HETATM 1303 C  CG2 . TPO A 1 164 ? -1.379  -12.741 2.861   1   22.02  ? 160 TPO A CG2 1 
HETATM 1304 O  OG1 . TPO A 1 164 ? -3.406  -11.521 2.545   1   26.35  ? 160 TPO A OG1 1 
HETATM 1305 P  P   . TPO A 1 164 ? -4.828  -11.509 3.298   1   24.5   ? 160 TPO A P   1 
HETATM 1306 O  O1P . TPO A 1 164 ? -5.718  -12.28  2.348   1   25.05  ? 160 TPO A O1P 1 
HETATM 1307 O  O2P . TPO A 1 164 ? -5.167  -10.038 3.479   1   20.86  ? 160 TPO A O2P 1 
HETATM 1308 O  O3P . TPO A 1 164 ? -4.719  -12.252 4.639   1   23.19  ? 160 TPO A O3P 1 
HETATM 1309 C  C   . TPO A 1 164 ? -2.045  -14.239 0.243   1   30.37  ? 160 TPO A C   1 
HETATM 1310 O  O   . TPO A 1 164 ? -2.616  -15.316 0.393   1   30.68  ? 160 TPO A O   1 
ATOM   1311 N  N   A HIS A 1 165 ? -0.863  -14.132 -0.374  0.5 34.32  ? 161 HIS A N   1 
ATOM   1312 N  N   B HIS A 1 165 ? -0.83   -14.074 -0.305  0.5 32.51  ? 161 HIS A N   1 
ATOM   1313 C  CA  A HIS A 1 165 ? -0.131  -15.332 -0.752  0.5 39.23  ? 161 HIS A CA  1 
ATOM   1314 C  CA  B HIS A 1 165 ? 0.04    -15.166 -0.717  0.5 35.68  ? 161 HIS A CA  1 
ATOM   1315 C  C   A HIS A 1 165 ? 0.716   -15.757 0.438   0.5 42.9   ? 161 HIS A C   1 
ATOM   1316 C  C   B HIS A 1 165 ? 0.697   -15.762 0.521   0.5 40.48  ? 161 HIS A C   1 
ATOM   1317 O  O   A HIS A 1 165 ? 0.991   -14.94  1.315   0.5 48.21  ? 161 HIS A O   1 
ATOM   1318 O  O   B HIS A 1 165 ? 0.833   -15.067 1.524   0.5 45.42  ? 161 HIS A O   1 
ATOM   1319 C  CB  A HIS A 1 165 ? 0.701   -15.106 -2.02   0.5 41.17  ? 161 HIS A CB  1 
ATOM   1320 C  CB  B HIS A 1 165 ? 1.123   -14.671 -1.687  0.5 33.48  ? 161 HIS A CB  1 
ATOM   1321 C  CG  A HIS A 1 165 ? 1.583   -16.246 -2.411  0.5 44.39  ? 161 HIS A CG  1 
ATOM   1322 C  CG  B HIS A 1 165 ? 2.202   -13.778 -1.136  0.5 33.12  ? 161 HIS A CG  1 
ATOM   1323 N  ND1 A HIS A 1 165 ? 2.904   -16.034 -2.74   0.5 52.12  ? 161 HIS A ND1 1 
ATOM   1324 N  ND1 B HIS A 1 165 ? 3.13    -13.18  -1.969  0.5 32.13  ? 161 HIS A ND1 1 
ATOM   1325 C  CD2 A HIS A 1 165 ? 1.381   -17.56  -2.519  0.5 40.25  ? 161 HIS A CD2 1 
ATOM   1326 C  CD2 B HIS A 1 165 ? 2.536   -13.393 0.116   0.5 33     ? 161 HIS A CD2 1 
ATOM   1327 C  CE1 A HIS A 1 165 ? 3.477   -17.192 -3.03   0.5 48.63  ? 161 HIS A CE1 1 
ATOM   1328 C  CE1 B HIS A 1 165 ? 3.979   -12.46  -1.246  0.5 31.01  ? 161 HIS A CE1 1 
ATOM   1329 N  NE2 A HIS A 1 165 ? 2.569   -18.132 -2.891  0.5 43.25  ? 161 HIS A NE2 1 
ATOM   1330 N  NE2 B HIS A 1 165 ? 3.636   -12.571 0.021   0.5 31.83  ? 161 HIS A NE2 1 
ATOM   1331 N  N   . GLU A 1 166 ? 1.135   -17.026 0.442   1   45.6   ? 162 GLU A N   1 
ATOM   1332 C  CA  . GLU A 1 166 ? 1.927   -17.595 1.53    1   60.19  ? 162 GLU A CA  1 
ATOM   1333 C  C   . GLU A 1 166 ? 1.091   -17.436 2.805   1   61.89  ? 162 GLU A C   1 
ATOM   1334 O  O   . GLU A 1 166 ? 1.374   -16.619 3.688   1   64.81  ? 162 GLU A O   1 
ATOM   1335 C  CB  . GLU A 1 166 ? 3.346   -17.001 1.607   1   71.77  ? 162 GLU A CB  1 
ATOM   1336 C  CG  . GLU A 1 166 ? 4.114   -16.964 0.282   1   72.37  ? 162 GLU A CG  1 
ATOM   1337 C  CD  . GLU A 1 166 ? 5.422   -16.186 0.255   1   74.4   ? 162 GLU A CD  1 
ATOM   1338 O  OE1 . GLU A 1 166 ? 6.005   -15.978 -0.829  1   76.1   ? 162 GLU A OE1 1 
ATOM   1339 O  OE2 . GLU A 1 166 ? 5.868   -15.79  1.344   1   84.26  ? 162 GLU A OE2 1 
ATOM   1340 N  N   . VAL A 1 167 ? -0.051  -18.121 2.778   1   50.18  ? 163 VAL A N   1 
ATOM   1341 C  CA  . VAL A 1 167 ? -0.894  -18.331 3.936   1   40.22  ? 163 VAL A CA  1 
ATOM   1342 C  C   . VAL A 1 167 ? -0.823  -19.821 4.224   1   36.74  ? 163 VAL A C   1 
ATOM   1343 O  O   . VAL A 1 167 ? -0.372  -20.588 3.368   1   35.59  ? 163 VAL A O   1 
ATOM   1344 C  CB  . VAL A 1 167 ? -2.343  -17.896 3.658   1   38.5   ? 163 VAL A CB  1 
ATOM   1345 C  CG1 . VAL A 1 167 ? -2.456  -16.391 3.744   1   40.85  ? 163 VAL A CG1 1 
ATOM   1346 C  CG2 . VAL A 1 167 ? -2.87   -18.398 2.313   1   32.49  ? 163 VAL A CG2 1 
ATOM   1347 N  N   . VAL A 1 168 ? -1.266  -20.206 5.428   1   30.28  ? 164 VAL A N   1 
ATOM   1348 C  CA  . VAL A 1 168 ? -1.223  -21.593 5.859   1   27.86  ? 164 VAL A CA  1 
ATOM   1349 C  C   . VAL A 1 168 ? 0.206   -21.93  6.295   1   29.44  ? 164 VAL A C   1 
ATOM   1350 O  O   . VAL A 1 168 ? 1.153   -21.803 5.509   1   26.51  ? 164 VAL A O   1 
ATOM   1351 C  CB  . VAL A 1 168 ? -1.727  -22.549 4.754   1   24.34  ? 164 VAL A CB  1 
ATOM   1352 C  CG1 . VAL A 1 168 ? -2.003  -23.935 5.31    1   22.82  ? 164 VAL A CG1 1 
ATOM   1353 C  CG2 . VAL A 1 168 ? -2.988  -22.02  4.063   1   22.45  ? 164 VAL A CG2 1 
ATOM   1354 N  N   . THR A 1 169 ? 0.359   -22.363 7.558   1   25.87  ? 165 THR A N   1 
ATOM   1355 C  CA  . THR A 1 169 ? 1.588   -23.014 7.993   1   24.59  ? 165 THR A CA  1 
ATOM   1356 C  C   . THR A 1 169 ? 2.047   -24.029 6.93    1   26.28  ? 165 THR A C   1 
ATOM   1357 O  O   . THR A 1 169 ? 1.28    -24.897 6.47    1   23.7   ? 165 THR A O   1 
ATOM   1358 C  CB  . THR A 1 169 ? 1.333   -23.695 9.339   1   23.96  ? 165 THR A CB  1 
ATOM   1359 O  OG1 . THR A 1 169 ? 0.855   -22.707 10.235  1   26.83  ? 165 THR A OG1 1 
ATOM   1360 C  CG2 . THR A 1 169 ? 2.582   -24.3   9.944   1   21.79  ? 165 THR A CG2 1 
ATOM   1361 N  N   . LEU A 1 170 ? 3.346   -23.958 6.612   1   25.81  ? 166 LEU A N   1 
ATOM   1362 C  CA  . LEU A 1 170 ? 3.935   -24.595 5.449   1   26.98  ? 166 LEU A CA  1 
ATOM   1363 C  C   . LEU A 1 170 ? 3.519   -26.063 5.331   1   29.06  ? 166 LEU A C   1 
ATOM   1364 O  O   . LEU A 1 170 ? 3.048   -26.465 4.269   1   27.33  ? 166 LEU A O   1 
ATOM   1365 C  CB  . LEU A 1 170 ? 5.45    -24.464 5.557   1   30.02  ? 166 LEU A CB  1 
ATOM   1366 C  CG  . LEU A 1 170 ? 6.244   -24.957 4.339   1   31.36  ? 166 LEU A CG  1 
ATOM   1367 C  CD1 . LEU A 1 170 ? 6.021   -24.04  3.129   1   31.68  ? 166 LEU A CD1 1 
ATOM   1368 C  CD2 . LEU A 1 170 ? 7.709   -25.034 4.71    1   23.99  ? 166 LEU A CD2 1 
ATOM   1369 N  N   . TRP A 1 171 ? 3.682   -26.854 6.411   1   26.51  ? 167 TRP A N   1 
ATOM   1370 C  CA  . TRP A 1 171 ? 3.475   -28.298 6.325   1   23.59  ? 167 TRP A CA  1 
ATOM   1371 C  C   . TRP A 1 171 ? 2.081   -28.638 5.805   1   25.94  ? 167 TRP A C   1 
ATOM   1372 O  O   . TRP A 1 171 ? 1.887   -29.726 5.27    1   28.48  ? 167 TRP A O   1 
ATOM   1373 C  CB  . TRP A 1 171 ? 3.692   -28.997 7.665   1   20.69  ? 167 TRP A CB  1 
ATOM   1374 C  CG  . TRP A 1 171 ? 5.108   -28.965 8.159   1   20.05  ? 167 TRP A CG  1 
ATOM   1375 C  CD1 . TRP A 1 171 ? 6.234   -28.536 7.507   1   20.67  ? 167 TRP A CD1 1 
ATOM   1376 C  CD2 . TRP A 1 171 ? 5.545   -29.465 9.427   1   19.28  ? 167 TRP A CD2 1 
ATOM   1377 N  NE1 . TRP A 1 171 ? 7.34    -28.716 8.292   1   19.27  ? 167 TRP A NE1 1 
ATOM   1378 C  CE2 . TRP A 1 171 ? 6.953   -29.306 9.468   1   20.86  ? 167 TRP A CE2 1 
ATOM   1379 C  CE3 . TRP A 1 171 ? 4.892   -30.058 10.514  1   20.81  ? 167 TRP A CE3 1 
ATOM   1380 C  CZ2 . TRP A 1 171 ? 7.713   -29.705 10.573  1   20.28  ? 167 TRP A CZ2 1 
ATOM   1381 C  CZ3 . TRP A 1 171 ? 5.649   -30.454 11.601  1   20.84  ? 167 TRP A CZ3 1 
ATOM   1382 C  CH2 . TRP A 1 171 ? 7.042   -30.279 11.633  1   18.86  ? 167 TRP A CH2 1 
ATOM   1383 N  N   . TYR A 1 172 ? 1.136   -27.692 5.938   1   26.23  ? 168 TYR A N   1 
ATOM   1384 C  CA  . TYR A 1 172 ? -0.275  -27.911 5.66    1   25.26  ? 168 TYR A CA  1 
ATOM   1385 C  C   . TYR A 1 172 ? -0.686  -27.12  4.415   1   25.02  ? 168 TYR A C   1 
ATOM   1386 O  O   . TYR A 1 172 ? -1.86   -27.117 4.06    1   24.67  ? 168 TYR A O   1 
ATOM   1387 C  CB  . TYR A 1 172 ? -1.115  -27.614 6.915   1   23.72  ? 168 TYR A CB  1 
ATOM   1388 C  CG  . TYR A 1 172 ? -0.615  -28.386 8.133   1   23.17  ? 168 TYR A CG  1 
ATOM   1389 C  CD1 . TYR A 1 172 ? -1.048  -29.684 8.367   1   23.25  ? 168 TYR A CD1 1 
ATOM   1390 C  CD2 . TYR A 1 172 ? 0.348   -27.848 8.999   1   21.75  ? 168 TYR A CD2 1 
ATOM   1391 C  CE1 . TYR A 1 172 ? -0.559  -30.43  9.427   1   23.17  ? 168 TYR A CE1 1 
ATOM   1392 C  CE2 . TYR A 1 172 ? 0.855   -28.582 10.052  1   21.2   ? 168 TYR A CE2 1 
ATOM   1393 C  CZ  . TYR A 1 172 ? 0.387   -29.869 10.273  1   24.38  ? 168 TYR A CZ  1 
ATOM   1394 O  OH  . TYR A 1 172 ? 0.867   -30.604 11.313  1   24.39  ? 168 TYR A OH  1 
ATOM   1395 N  N   . ARG A 1 173 ? 0.28    -26.47  3.745   1   23.91  ? 169 ARG A N   1 
ATOM   1396 C  CA  . ARG A 1 173 ? -0.025  -25.515 2.68    1   24.45  ? 169 ARG A CA  1 
ATOM   1397 C  C   . ARG A 1 173 ? -0.252  -26.23  1.346   1   25.88  ? 169 ARG A C   1 
ATOM   1398 O  O   . ARG A 1 173 ? 0.557   -27.059 0.908   1   25.29  ? 169 ARG A O   1 
ATOM   1399 C  CB  . ARG A 1 173 ? 1.138   -24.525 2.547   1   22.93  ? 169 ARG A CB  1 
ATOM   1400 C  CG  . ARG A 1 173 ? 0.904   -23.442 1.512   1   23.59  ? 169 ARG A CG  1 
ATOM   1401 C  CD  . ARG A 1 173 ? 2.021   -22.429 1.569   1   25.25  ? 169 ARG A CD  1 
ATOM   1402 N  NE  . ARG A 1 173 ? 2.254   -21.899 2.92    1   25.52  ? 169 ARG A NE  1 
ATOM   1403 C  CZ  . ARG A 1 173 ? 3.312   -21.167 3.287   1   24.78  ? 169 ARG A CZ  1 
ATOM   1404 N  NH1 . ARG A 1 173 ? 4.276   -20.886 2.436   1   23.95  ? 169 ARG A NH1 1 
ATOM   1405 N  NH2 . ARG A 1 173 ? 3.416   -20.745 4.526   1   24.27  ? 169 ARG A NH2 1 
ATOM   1406 N  N   . ALA A 1 174 ? -1.352  -25.875 0.683   1   25.05  ? 170 ALA A N   1 
ATOM   1407 C  CA  . ALA A 1 174 ? -1.755  -26.545 -0.548  1   26.18  ? 170 ALA A CA  1 
ATOM   1408 C  C   . ALA A 1 174 ? -0.811  -26.198 -1.69   1   28.82  ? 170 ALA A C   1 
ATOM   1409 O  O   . ALA A 1 174 ? -0.272  -25.094 -1.74   1   33.56  ? 170 ALA A O   1 
ATOM   1410 C  CB  . ALA A 1 174 ? -3.169  -26.153 -0.906  1   24.96  ? 170 ALA A CB  1 
ATOM   1411 N  N   . PRO A 1 175 ? -0.654  -27.099 -2.682  1   31.07  ? 171 PRO A N   1 
ATOM   1412 C  CA  . PRO A 1 175 ? 0.289   -26.879 -3.789  1   27.75  ? 171 PRO A CA  1 
ATOM   1413 C  C   . PRO A 1 175 ? 0.047   -25.588 -4.565  1   26.79  ? 171 PRO A C   1 
ATOM   1414 O  O   . PRO A 1 175 ? 0.988   -24.916 -4.999  1   26.74  ? 171 PRO A O   1 
ATOM   1415 C  CB  . PRO A 1 175 ? 0.168   -28.129 -4.694  1   27.42  ? 171 PRO A CB  1 
ATOM   1416 C  CG  . PRO A 1 175 ? -1.106  -28.803 -4.226  1   30.73  ? 171 PRO A CG  1 
ATOM   1417 C  CD  . PRO A 1 175 ? -1.386  -28.376 -2.786  1   29.76  ? 171 PRO A CD  1 
ATOM   1418 N  N   . GLU A 1 176 ? -1.23   -25.24  -4.735  1   25.2   ? 172 GLU A N   1 
ATOM   1419 C  CA  . GLU A 1 176 ? -1.568  -24.124 -5.604  1   24.01  ? 172 GLU A CA  1 
ATOM   1420 C  C   . GLU A 1 176 ? -1.006  -22.834 -4.996  1   26.88  ? 172 GLU A C   1 
ATOM   1421 O  O   . GLU A 1 176 ? -0.646  -21.896 -5.711  1   25.85  ? 172 GLU A O   1 
ATOM   1422 C  CB  . GLU A 1 176 ? -3.062  -24.107 -5.943  1   22.59  ? 172 GLU A CB  1 
ATOM   1423 C  CG  . GLU A 1 176 ? -3.993  -24.103 -4.74   1   24.46  ? 172 GLU A CG  1 
ATOM   1424 C  CD  . GLU A 1 176 ? -4.51   -25.438 -4.19   1   26.71  ? 172 GLU A CD  1 
ATOM   1425 O  OE1 . GLU A 1 176 ? -5.643  -25.484 -3.649  1   26.02  ? 172 GLU A OE1 1 
ATOM   1426 O  OE2 . GLU A 1 176 ? -3.794  -26.452 -4.306  1   26.27  ? 172 GLU A OE2 1 
ATOM   1427 N  N   . ILE A 1 177 ? -0.888  -22.811 -3.658  1   24.78  ? 173 ILE A N   1 
ATOM   1428 C  CA  . ILE A 1 177 ? -0.287  -21.683 -2.957  1   23.21  ? 173 ILE A CA  1 
ATOM   1429 C  C   . ILE A 1 177 ? 1.227   -21.715 -3.153  1   21.93  ? 173 ILE A C   1 
ATOM   1430 O  O   . ILE A 1 177 ? 1.86    -20.705 -3.452  1   19.71  ? 173 ILE A O   1 
ATOM   1431 C  CB  . ILE A 1 177 ? -0.674  -21.699 -1.465  1   25.47  ? 173 ILE A CB  1 
ATOM   1432 C  CG1 . ILE A 1 177 ? -2.192  -21.674 -1.287  1   25.85  ? 173 ILE A CG1 1 
ATOM   1433 C  CG2 . ILE A 1 177 ? -0.014  -20.542 -0.725  1   21.59  ? 173 ILE A CG2 1 
ATOM   1434 C  CD1 . ILE A 1 177 ? -2.662  -21.947 0.129   1   28.61  ? 173 ILE A CD1 1 
ATOM   1435 N  N   . LEU A 1 178 ? 1.816   -22.891 -2.948  1   22.57  ? 174 LEU A N   1 
ATOM   1436 C  CA  . LEU A 1 178 ? 3.24    -23.063 -3.156  1   22.07  ? 174 LEU A CA  1 
ATOM   1437 C  C   . LEU A 1 178 ? 3.637   -22.684 -4.588  1   24.63  ? 174 LEU A C   1 
ATOM   1438 O  O   . LEU A 1 178 ? 4.752   -22.18  -4.782  1   26.91  ? 174 LEU A O   1 
ATOM   1439 C  CB  . LEU A 1 178 ? 3.613   -24.498 -2.799  1   20.71  ? 174 LEU A CB  1 
ATOM   1440 C  CG  . LEU A 1 178 ? 3.443   -24.875 -1.328  1   19.44  ? 174 LEU A CG  1 
ATOM   1441 C  CD1 . LEU A 1 178 ? 3.369   -26.391 -1.247  1   20.19  ? 174 LEU A CD1 1 
ATOM   1442 C  CD2 . LEU A 1 178 ? 4.624   -24.355 -0.544  1   18.14  ? 174 LEU A CD2 1 
ATOM   1443 N  N   . LEU A 1 179 ? 2.735   -22.884 -5.574  1   22.22  ? 175 LEU A N   1 
ATOM   1444 C  CA  . LEU A 1 179 ? 3.038   -22.541 -6.963  1   23.23  ? 175 LEU A CA  1 
ATOM   1445 C  C   . LEU A 1 179 ? 2.692   -21.096 -7.326  1   25.03  ? 175 LEU A C   1 
ATOM   1446 O  O   . LEU A 1 179 ? 2.701   -20.721 -8.506  1   25.55  ? 175 LEU A O   1 
ATOM   1447 C  CB  . LEU A 1 179 ? 2.327   -23.528 -7.882  1   23.27  ? 175 LEU A CB  1 
ATOM   1448 C  CG  . LEU A 1 179 ? 2.848   -24.962 -7.805  1   23.79  ? 175 LEU A CG  1 
ATOM   1449 C  CD1 . LEU A 1 179 ? 1.989   -25.854 -8.659  1   26.15  ? 175 LEU A CD1 1 
ATOM   1450 C  CD2 . LEU A 1 179 ? 4.308   -25.01  -8.226  1   23.77  ? 175 LEU A CD2 1 
ATOM   1451 N  N   . GLY A 1 180 ? 2.379   -20.28  -6.316  1   25.36  ? 176 GLY A N   1 
ATOM   1452 C  CA  . GLY A 1 180 ? 2.135   -18.865 -6.53   1   25.53  ? 176 GLY A CA  1 
ATOM   1453 C  C   . GLY A 1 180 ? 0.871   -18.607 -7.344  1   29.8   ? 176 GLY A C   1 
ATOM   1454 O  O   . GLY A 1 180 ? 0.814   -17.653 -8.117  1   33.64  ? 176 GLY A O   1 
ATOM   1455 N  N   . CYS A 1 181 ? -0.15   -19.452 -7.145  1   27.05  ? 177 CYS A N   1 
ATOM   1456 C  CA  . CYS A 1 181 ? -1.421  -19.33  -7.852  1   26.31  ? 177 CYS A CA  1 
ATOM   1457 C  C   . CYS A 1 181 ? -1.987  -17.919 -7.713  1   27.13  ? 177 CYS A C   1 
ATOM   1458 O  O   . CYS A 1 181 ? -1.88   -17.306 -6.652  1   26.54  ? 177 CYS A O   1 
ATOM   1459 C  CB  . CYS A 1 181 ? -2.478  -20.262 -7.263  1   23.97  ? 177 CYS A CB  1 
ATOM   1460 S  SG  . CYS A 1 181 ? -2.74   -20.051 -5.481  1   17.33  ? 177 CYS A SG  1 
ATOM   1461 N  N   . LYS A 1 182 ? -2.61   -17.422 -8.788  1   30.44  ? 178 LYS A N   1 
ATOM   1462 C  CA  . LYS A 1 182 ? -3.309  -16.139 -8.739  1   28.74  ? 178 LYS A CA  1 
ATOM   1463 C  C   . LYS A 1 182 ? -4.501  -16.196 -7.774  1   25.06  ? 178 LYS A C   1 
ATOM   1464 O  O   . LYS A 1 182 ? -4.776  -15.237 -7.063  1   25.38  ? 178 LYS A O   1 
ATOM   1465 C  CB  . LYS A 1 182 ? -3.745  -15.733 -10.148 1   33.22  ? 178 LYS A CB  1 
ATOM   1466 C  CG  . LYS A 1 182 ? -4.313  -14.326 -10.283 1   42.45  ? 178 LYS A CG  1 
ATOM   1467 C  CD  . LYS A 1 182 ? -4.746  -13.916 -11.696 1   47.05  ? 178 LYS A CD  1 
ATOM   1468 C  CE  . LYS A 1 182 ? -4.988  -12.424 -11.749 1   53.16  ? 178 LYS A CE  1 
ATOM   1469 N  NZ  . LYS A 1 182 ? -5.818  -11.988 -12.876 1   57.8   ? 178 LYS A NZ  1 
ATOM   1470 N  N   . TYR A 1 183 ? -5.231  -17.313 -7.783  1   22.99  ? 179 TYR A N   1 
ATOM   1471 C  CA  . TYR A 1 183 ? -6.451  -17.474 -7.018  1   21.37  ? 179 TYR A CA  1 
ATOM   1472 C  C   . TYR A 1 183 ? -6.39   -18.79  -6.25   1   23.93  ? 179 TYR A C   1 
ATOM   1473 O  O   . TYR A 1 183 ? -5.834  -19.78  -6.725  1   23.67  ? 179 TYR A O   1 
ATOM   1474 C  CB  . TYR A 1 183 ? -7.578  -17.611 -8.039  1   21.44  ? 179 TYR A CB  1 
ATOM   1475 C  CG  . TYR A 1 183 ? -7.878  -16.375 -8.879  1   22.07  ? 179 TYR A CG  1 
ATOM   1476 C  CD1 . TYR A 1 183 ? -8.174  -15.15  -8.29   1   21.71  ? 179 TYR A CD1 1 
ATOM   1477 C  CD2 . TYR A 1 183 ? -7.871  -16.444 -10.266 1   21.02  ? 179 TYR A CD2 1 
ATOM   1478 C  CE1 . TYR A 1 183 ? -8.454  -14.032 -9.061  1   22.61  ? 179 TYR A CE1 1 
ATOM   1479 C  CE2 . TYR A 1 183 ? -8.155  -15.337 -11.046 1   22.36  ? 179 TYR A CE2 1 
ATOM   1480 C  CZ  . TYR A 1 183 ? -8.435  -14.128 -10.44  1   23.47  ? 179 TYR A CZ  1 
ATOM   1481 O  OH  . TYR A 1 183 ? -8.736  -13.038 -11.197 1   25.12  ? 179 TYR A OH  1 
ATOM   1482 N  N   . TYR A 1 184 ? -6.944  -18.781 -5.039  1   23.09  ? 180 TYR A N   1 
ATOM   1483 C  CA  . TYR A 1 184 ? -7.153  -19.994 -4.262  1   25.71  ? 180 TYR A CA  1 
ATOM   1484 C  C   . TYR A 1 184 ? -8.516  -19.878 -3.552  1   29.12  ? 180 TYR A C   1 
ATOM   1485 O  O   . TYR A 1 184 ? -9.092  -18.78  -3.434  1   27.78  ? 180 TYR A O   1 
ATOM   1486 C  CB  . TYR A 1 184 ? -5.976  -20.317 -3.326  1   23.93  ? 180 TYR A CB  1 
ATOM   1487 C  CG  . TYR A 1 184 ? -5.756  -19.301 -2.203  1   26.23  ? 180 TYR A CG  1 
ATOM   1488 C  CD1 . TYR A 1 184 ? -6.563  -19.259 -1.06   1   23.89  ? 180 TYR A CD1 1 
ATOM   1489 C  CD2 . TYR A 1 184 ? -4.725  -18.37  -2.291  1   26.34  ? 180 TYR A CD2 1 
ATOM   1490 C  CE1 . TYR A 1 184 ? -6.338  -18.336 -0.046  1   23.75  ? 180 TYR A CE1 1 
ATOM   1491 C  CE2 . TYR A 1 184 ? -4.491  -17.438 -1.292  1   25.32  ? 180 TYR A CE2 1 
ATOM   1492 C  CZ  . TYR A 1 184 ? -5.297  -17.421 -0.165  1   26.4   ? 180 TYR A CZ  1 
ATOM   1493 O  OH  . TYR A 1 184 ? -5.007  -16.481 0.787   1   25.09  ? 180 TYR A OH  1 
ATOM   1494 N  N   . SER A 1 185 ? -9.013  -21.03  -3.072  1   25.19  ? 181 SER A N   1 
ATOM   1495 C  CA  . SER A 1 185 ? -10.405 -21.162 -2.685  1   26.01  ? 181 SER A CA  1 
ATOM   1496 C  C   . SER A 1 185 ? -10.53  -22.135 -1.516  1   27.3   ? 181 SER A C   1 
ATOM   1497 O  O   . SER A 1 185 ? -9.562  -22.4   -0.796  1   26.71  ? 181 SER A O   1 
ATOM   1498 C  CB  . SER A 1 185 ? -11.265 -21.601 -3.853  1   24.62  ? 181 SER A CB  1 
ATOM   1499 O  OG  . SER A 1 185 ? -12.627 -21.215 -3.678  1   24.06  ? 181 SER A OG  1 
ATOM   1500 N  N   . THR A 1 186 ? -11.748 -22.668 -1.357  1   26.66  ? 182 THR A N   1 
ATOM   1501 C  CA  . THR A 1 186 ? -12.092 -23.552 -0.247  1   25     ? 182 THR A CA  1 
ATOM   1502 C  C   . THR A 1 186 ? -11.163 -24.761 -0.233  1   24.98  ? 182 THR A C   1 
ATOM   1503 O  O   . THR A 1 186 ? -10.933 -25.337 0.815   1   27.59  ? 182 THR A O   1 
ATOM   1504 C  CB  . THR A 1 186 ? -13.577 -23.908 -0.348  1   21.66  ? 182 THR A CB  1 
ATOM   1505 O  OG1 . THR A 1 186 ? -13.859 -24.202 -1.717  1   23.51  ? 182 THR A OG1 1 
ATOM   1506 C  CG2 . THR A 1 186 ? -14.471 -22.743 0.058   1   18.06  ? 182 THR A CG2 1 
ATOM   1507 N  N   . ALA A 1 187 ? -10.611 -25.117 -1.4    1   24.21  ? 183 ALA A N   1 
ATOM   1508 C  CA  . ALA A 1 187 ? -9.807  -26.313 -1.569  1   24.95  ? 183 ALA A CA  1 
ATOM   1509 C  C   . ALA A 1 187 ? -8.524  -26.3   -0.719  1   27.94  ? 183 ALA A C   1 
ATOM   1510 O  O   . ALA A 1 187 ? -7.997  -27.367 -0.387  1   25.88  ? 183 ALA A O   1 
ATOM   1511 C  CB  . ALA A 1 187 ? -9.523  -26.507 -3.035  1   22.82  ? 183 ALA A CB  1 
ATOM   1512 N  N   . VAL A 1 188 ? -8      -25.108 -0.382  1   27.11  ? 184 VAL A N   1 
ATOM   1513 C  CA  . VAL A 1 188 ? -6.794  -25.035 0.424   1   24.46  ? 184 VAL A CA  1 
ATOM   1514 C  C   . VAL A 1 188 ? -7.089  -25.538 1.839   1   28.58  ? 184 VAL A C   1 
ATOM   1515 O  O   . VAL A 1 188 ? -6.212  -26.145 2.458   1   31.3   ? 184 VAL A O   1 
ATOM   1516 C  CB  . VAL A 1 188 ? -6.158  -23.638 0.468   1   24.33  ? 184 VAL A CB  1 
ATOM   1517 C  CG1 . VAL A 1 188 ? -6.029  -23.04  -0.924  1   22.44  ? 184 VAL A CG1 1 
ATOM   1518 C  CG2 . VAL A 1 188 ? -6.909  -22.715 1.42    1   22.38  ? 184 VAL A CG2 1 
ATOM   1519 N  N   . ASP A 1 189 ? -8.314  -25.302 2.351   1   25.4   ? 185 ASP A N   1 
ATOM   1520 C  CA  . ASP A 1 189 ? -8.666  -25.776 3.679   1   24.35  ? 185 ASP A CA  1 
ATOM   1521 C  C   . ASP A 1 189 ? -8.789  -27.295 3.659   1   26.6   ? 185 ASP A C   1 
ATOM   1522 O  O   . ASP A 1 189 ? -8.41   -27.969 4.627   1   27.59  ? 185 ASP A O   1 
ATOM   1523 C  CB  . ASP A 1 189 ? -9.928  -25.142 4.235   1   23.37  ? 185 ASP A CB  1 
ATOM   1524 C  CG  . ASP A 1 189 ? -9.8    -23.699 4.673   1   23.48  ? 185 ASP A CG  1 
ATOM   1525 O  OD1 . ASP A 1 189 ? -8.681  -23.305 5.049   1   25.88  ? 185 ASP A OD1 1 
ATOM   1526 O  OD2 . ASP A 1 189 ? -10.817 -22.984 4.634   1   24.07  ? 185 ASP A OD2 1 
ATOM   1527 N  N   . ILE A 1 190 ? -9.343  -27.829 2.562   1   26.09  ? 186 ILE A N   1 
ATOM   1528 C  CA  . ILE A 1 190 ? -9.442  -29.274 2.424   1   24.54  ? 186 ILE A CA  1 
ATOM   1529 C  C   . ILE A 1 190 ? -8.057  -29.912 2.434   1   25.13  ? 186 ILE A C   1 
ATOM   1530 O  O   . ILE A 1 190 ? -7.835  -30.937 3.097   1   26.08  ? 186 ILE A O   1 
ATOM   1531 C  CB  . ILE A 1 190 ? -10.295 -29.688 1.213   1   23.74  ? 186 ILE A CB  1 
ATOM   1532 C  CG1 . ILE A 1 190 ? -11.777 -29.459 1.52    1   19.77  ? 186 ILE A CG1 1 
ATOM   1533 C  CG2 . ILE A 1 190 ? -10.001 -31.134 0.803   1   21.88  ? 186 ILE A CG2 1 
ATOM   1534 C  CD1 . ILE A 1 190 ? -12.309 -30.247 2.697   1   19.46  ? 186 ILE A CD1 1 
ATOM   1535 N  N   . TRP A 1 191 ? -7.118  -29.283 1.724   1   25.21  ? 187 TRP A N   1 
ATOM   1536 C  CA  . TRP A 1 191 ? -5.78   -29.845 1.646   1   27.17  ? 187 TRP A CA  1 
ATOM   1537 C  C   . TRP A 1 191 ? -5.217  -30.013 3.061   1   27.64  ? 187 TRP A C   1 
ATOM   1538 O  O   . TRP A 1 191 ? -4.695  -31.073 3.41    1   33.11  ? 187 TRP A O   1 
ATOM   1539 C  CB  . TRP A 1 191 ? -4.88   -28.961 0.77    1   25.56  ? 187 TRP A CB  1 
ATOM   1540 C  CG  . TRP A 1 191 ? -3.474  -29.481 0.715   1   25.71  ? 187 TRP A CG  1 
ATOM   1541 C  CD1 . TRP A 1 191 ? -2.502  -29.293 1.65    1   25.66  ? 187 TRP A CD1 1 
ATOM   1542 C  CD2 . TRP A 1 191 ? -2.917  -30.346 -0.289  1   24.76  ? 187 TRP A CD2 1 
ATOM   1543 N  NE1 . TRP A 1 191 ? -1.364  -29.952 1.28    1   26.21  ? 187 TRP A NE1 1 
ATOM   1544 C  CE2 . TRP A 1 191 ? -1.594  -30.616 0.104   1   25.17  ? 187 TRP A CE2 1 
ATOM   1545 C  CE3 . TRP A 1 191 ? -3.407  -30.923 -1.461  1   25.15  ? 187 TRP A CE3 1 
ATOM   1546 C  CZ2 . TRP A 1 191 ? -0.754  -31.437 -0.641  1   26.7   ? 187 TRP A CZ2 1 
ATOM   1547 C  CZ3 . TRP A 1 191 ? -2.57   -31.726 -2.2    1   25.98  ? 187 TRP A CZ3 1 
ATOM   1548 C  CH2 . TRP A 1 191 ? -1.266  -31.992 -1.79   1   25.5   ? 187 TRP A CH2 1 
ATOM   1549 N  N   . SER A 1 192 ? -5.326  -28.944 3.85    1   24.09  ? 188 SER A N   1 
ATOM   1550 C  CA  . SER A 1 192 ? -4.923  -28.91  5.241   1   24.29  ? 188 SER A CA  1 
ATOM   1551 C  C   . SER A 1 192 ? -5.555  -30.073 6.002   1   25.11  ? 188 SER A C   1 
ATOM   1552 O  O   . SER A 1 192 ? -4.86   -30.823 6.688   1   29.07  ? 188 SER A O   1 
ATOM   1553 C  CB  . SER A 1 192 ? -5.254  -27.577 5.874   1   24.95  ? 188 SER A CB  1 
ATOM   1554 O  OG  . SER A 1 192 ? -4.499  -26.514 5.309   1   25.11  ? 188 SER A OG  1 
ATOM   1555 N  N   . LEU A 1 193 ? -6.871  -30.248 5.86    1   26.15  ? 189 LEU A N   1 
ATOM   1556 C  CA  . LEU A 1 193 ? -7.557  -31.306 6.589   1   26.27  ? 189 LEU A CA  1 
ATOM   1557 C  C   . LEU A 1 193 ? -7.015  -32.677 6.187   1   26.69  ? 189 LEU A C   1 
ATOM   1558 O  O   . LEU A 1 193 ? -6.981  -33.587 7.013   1   25.67  ? 189 LEU A O   1 
ATOM   1559 C  CB  . LEU A 1 193 ? -9.057  -31.252 6.34    1   26.92  ? 189 LEU A CB  1 
ATOM   1560 C  CG  . LEU A 1 193 ? -9.876  -30.371 7.281   1   31.64  ? 189 LEU A CG  1 
ATOM   1561 C  CD1 . LEU A 1 193 ? -11.298 -30.867 7.231   1   31.85  ? 189 LEU A CD1 1 
ATOM   1562 C  CD2 . LEU A 1 193 ? -9.332  -30.389 8.699   1   34.5   ? 189 LEU A CD2 1 
ATOM   1563 N  N   . GLY A 1 194 ? -6.644  -32.825 4.909   1   23.36  ? 190 GLY A N   1 
ATOM   1564 C  CA  . GLY A 1 194 ? -6.106  -34.077 4.431   1   23.53  ? 190 GLY A CA  1 
ATOM   1565 C  C   . GLY A 1 194 ? -4.748  -34.368 5.057   1   25.71  ? 190 GLY A C   1 
ATOM   1566 O  O   . GLY A 1 194 ? -4.52   -35.472 5.567   1   27.6   ? 190 GLY A O   1 
ATOM   1567 N  N   . CYS A 1 195 ? -3.862  -33.364 5.057   1   24.83  ? 191 CYS A N   1 
ATOM   1568 C  CA  . CYS A 1 195 ? -2.625  -33.471 5.821   1   22.96  ? 191 CYS A CA  1 
ATOM   1569 C  C   . CYS A 1 195 ? -2.926  -33.909 7.263   1   23.72  ? 191 CYS A C   1 
ATOM   1570 O  O   . CYS A 1 195 ? -2.224  -34.765 7.818   1   22.11  ? 191 CYS A O   1 
ATOM   1571 C  CB  . CYS A 1 195 ? -1.905  -32.134 5.776   1   22.39  ? 191 CYS A CB  1 
ATOM   1572 S  SG  . CYS A 1 195 ? -1.361  -31.712 4.102   1   23.73  ? 191 CYS A SG  1 
ATOM   1573 N  N   . ILE A 1 196 ? -4.001  -33.348 7.857   1   20.85  ? 192 ILE A N   1 
ATOM   1574 C  CA  . ILE A 1 196 ? -4.309  -33.578 9.256   1   21.81  ? 192 ILE A CA  1 
ATOM   1575 C  C   . ILE A 1 196 ? -4.811  -35.001 9.452   1   23.06  ? 192 ILE A C   1 
ATOM   1576 O  O   . ILE A 1 196 ? -4.415  -35.651 10.42   1   22.27  ? 192 ILE A O   1 
ATOM   1577 C  CB  . ILE A 1 196 ? -5.275  -32.507 9.801   1   23.82  ? 192 ILE A CB  1 
ATOM   1578 C  CG1 . ILE A 1 196 ? -4.543  -31.18  9.883   1   22.49  ? 192 ILE A CG1 1 
ATOM   1579 C  CG2 . ILE A 1 196 ? -5.938  -32.91  11.141  1   20.23  ? 192 ILE A CG2 1 
ATOM   1580 C  CD1 . ILE A 1 196 ? -5.434  -30.034 10.294  1   23.03  ? 192 ILE A CD1 1 
ATOM   1581 N  N   . PHE A 1 197 ? -5.72   -35.437 8.56    1   25.07  ? 193 PHE A N   1 
ATOM   1582 C  CA  . PHE A 1 197 ? -6.207  -36.807 8.502   1   23.43  ? 193 PHE A CA  1 
ATOM   1583 C  C   . PHE A 1 197 ? -5.025  -37.774 8.554   1   22.26  ? 193 PHE A C   1 
ATOM   1584 O  O   . PHE A 1 197 ? -5.017  -38.679 9.382   1   23.74  ? 193 PHE A O   1 
ATOM   1585 C  CB  . PHE A 1 197 ? -7.05   -37.012 7.242   1   23.96  ? 193 PHE A CB  1 
ATOM   1586 C  CG  . PHE A 1 197 ? -7.67   -38.396 7.059   1   24.88  ? 193 PHE A CG  1 
ATOM   1587 C  CD1 . PHE A 1 197 ? -7.695  -39.337 8.106   1   22.5   ? 193 PHE A CD1 1 
ATOM   1588 C  CD2 . PHE A 1 197 ? -8.25   -38.748 5.833   1   22.51  ? 193 PHE A CD2 1 
ATOM   1589 C  CE1 . PHE A 1 197 ? -8.295  -40.582 7.921   1   20.86  ? 193 PHE A CE1 1 
ATOM   1590 C  CE2 . PHE A 1 197 ? -8.856  -39.99  5.655   1   20.01  ? 193 PHE A CE2 1 
ATOM   1591 C  CZ  . PHE A 1 197 ? -8.885  -40.899 6.698   1   20.99  ? 193 PHE A CZ  1 
ATOM   1592 N  N   . ALA A 1 198 ? -4.035  -37.576 7.677   1   21.45  ? 194 ALA A N   1 
ATOM   1593 C  CA  . ALA A 1 198 ? -2.908  -38.5   7.618   1   22.57  ? 194 ALA A CA  1 
ATOM   1594 C  C   . ALA A 1 198 ? -2.156  -38.487 8.951   1   25.62  ? 194 ALA A C   1 
ATOM   1595 O  O   . ALA A 1 198 ? -1.707  -39.538 9.434   1   26.05  ? 194 ALA A O   1 
ATOM   1596 C  CB  . ALA A 1 198 ? -2.004  -38.171 6.455   1   17.67  ? 194 ALA A CB  1 
ATOM   1597 N  N   . GLU A 1 199 ? -2.067  -37.287 9.552   1   24.7   ? 195 GLU A N   1 
ATOM   1598 C  CA  . GLU A 1 199 ? -1.255  -37.062 10.735  1   25.86  ? 195 GLU A CA  1 
ATOM   1599 C  C   . GLU A 1 199 ? -1.906  -37.699 11.965  1   25.53  ? 195 GLU A C   1 
ATOM   1600 O  O   . GLU A 1 199 ? -1.232  -38.229 12.845  1   28.02  ? 195 GLU A O   1 
ATOM   1601 C  CB  . GLU A 1 199 ? -0.99   -35.564 10.888  1   25.56  ? 195 GLU A CB  1 
ATOM   1602 C  CG  . GLU A 1 199 ? -0.035  -35.232 12.029  1   24.17  ? 195 GLU A CG  1 
ATOM   1603 C  CD  . GLU A 1 199 ? 0.423   -33.788 12.078  1   25.61  ? 195 GLU A CD  1 
ATOM   1604 O  OE1 . GLU A 1 199 ? 0.155   -33.058 11.095  1   23.47  ? 195 GLU A OE1 1 
ATOM   1605 O  OE2 . GLU A 1 199 ? 1.038   -33.396 13.105  1   27.69  ? 195 GLU A OE2 1 
ATOM   1606 N  N   . MET A 1 200 ? -3.23   -37.643 12.032  1   24.31  ? 196 MET A N   1 
ATOM   1607 C  CA  . MET A 1 200 ? -3.945  -38.371 13.063  1   24.91  ? 196 MET A CA  1 
ATOM   1608 C  C   . MET A 1 200 ? -3.71   -39.876 12.968  1   26.43  ? 196 MET A C   1 
ATOM   1609 O  O   . MET A 1 200 ? -3.822  -40.546 13.984  1   26.98  ? 196 MET A O   1 
ATOM   1610 C  CB  . MET A 1 200 ? -5.448  -38.115 12.954  1   25.45  ? 196 MET A CB  1 
ATOM   1611 C  CG  . MET A 1 200 ? -5.812  -36.747 13.46   1   26.44  ? 196 MET A CG  1 
ATOM   1612 S  SD  . MET A 1 200 ? -7.591  -36.652 13.662  1   28.81  ? 196 MET A SD  1 
ATOM   1613 C  CE  . MET A 1 200 ? -8.146  -36.578 11.952  1   26.11  ? 196 MET A CE  1 
ATOM   1614 N  N   . VAL A 1 201 ? -3.411  -40.409 11.769  1   25.22  ? 197 VAL A N   1 
ATOM   1615 C  CA  . VAL A 1 201 ? -3.215  -41.84  11.613  1   24.13  ? 197 VAL A CA  1 
ATOM   1616 C  C   . VAL A 1 201 ? -1.812  -42.214 12.088  1   24.37  ? 197 VAL A C   1 
ATOM   1617 O  O   . VAL A 1 201 ? -1.66   -43.161 12.851  1   26.26  ? 197 VAL A O   1 
ATOM   1618 C  CB  . VAL A 1 201 ? -3.517  -42.396 10.202  1   23.69  ? 197 VAL A CB  1 
ATOM   1619 C  CG1 . VAL A 1 201 ? -3.029  -43.828 10.094  1   22.01  ? 197 VAL A CG1 1 
ATOM   1620 C  CG2 . VAL A 1 201 ? -4.997  -42.34  9.819   1   19.18  ? 197 VAL A CG2 1 
ATOM   1621 N  N   . THR A 1 202 ? -0.799  -41.457 11.639  1   25.89  ? 198 THR A N   1 
ATOM   1622 C  CA  . THR A 1 202 ? 0.619   -41.763 11.854  1   26.59  ? 198 THR A CA  1 
ATOM   1623 C  C   . THR A 1 202 ? 1.145   -41.035 13.085  1   28.45  ? 198 THR A C   1 
ATOM   1624 O  O   . THR A 1 202 ? 2.128   -41.456 13.676  1   30.53  ? 198 THR A O   1 
ATOM   1625 C  CB  . THR A 1 202 ? 1.473   -41.312 10.67   1   27.4   ? 198 THR A CB  1 
ATOM   1626 O  OG1 . THR A 1 202 ? 1.23    -39.907 10.588  1   35.63  ? 198 THR A OG1 1 
ATOM   1627 C  CG2 . THR A 1 202 ? 1.061   -41.923 9.351   1   25.04  ? 198 THR A CG2 1 
ATOM   1628 N  N   . ARG A 1 203 ? 0.543   -39.89  13.411  1   32.04  ? 199 ARG A N   1 
ATOM   1629 C  CA  . ARG A 1 203 ? 1.044   -39.007 14.455  1   36.39  ? 199 ARG A CA  1 
ATOM   1630 C  C   . ARG A 1 203 ? 2.363   -38.365 14.036  1   33.47  ? 199 ARG A C   1 
ATOM   1631 O  O   . ARG A 1 203 ? 3.092   -37.907 14.903  1   34.28  ? 199 ARG A O   1 
ATOM   1632 C  CB  . ARG A 1 203 ? 1.215   -39.668 15.831  1   39.03  ? 199 ARG A CB  1 
ATOM   1633 C  CG  . ARG A 1 203 ? -0.082  -39.825 16.608  1   39.84  ? 199 ARG A CG  1 
ATOM   1634 C  CD  . ARG A 1 203 ? -0.073  -41.087 17.444  1   39.66  ? 199 ARG A CD  1 
ATOM   1635 N  NE  . ARG A 1 203 ? -0.143  -42.212 16.509  1   41.86  ? 199 ARG A NE  1 
ATOM   1636 C  CZ  . ARG A 1 203 ? 0.684   -43.241 16.444  1   44.36  ? 199 ARG A CZ  1 
ATOM   1637 N  NH1 . ARG A 1 203 ? 1.67    -43.404 17.316  1   43.26  ? 199 ARG A NH1 1 
ATOM   1638 N  NH2 . ARG A 1 203 ? 0.502   -44.123 15.484  1   46.88  ? 199 ARG A NH2 1 
ATOM   1639 N  N   . ARG A 1 204 ? 2.652   -38.323 12.728  1   31.19  ? 200 ARG A N   1 
ATOM   1640 C  CA  . ARG A 1 204 ? 3.723   -37.481 12.201  1   31.76  ? 200 ARG A CA  1 
ATOM   1641 C  C   . ARG A 1 204 ? 3.219   -36.688 10.986  1   29.78  ? 200 ARG A C   1 
ATOM   1642 O  O   . ARG A 1 204 ? 2.306   -37.14  10.298  1   32.2   ? 200 ARG A O   1 
ATOM   1643 C  CB  . ARG A 1 204 ? 4.917   -38.376 11.867  1   33.57  ? 200 ARG A CB  1 
ATOM   1644 C  CG  . ARG A 1 204 ? 4.775   -39.029 10.499  1   39.78  ? 200 ARG A CG  1 
ATOM   1645 C  CD  . ARG A 1 204 ? 5.737   -40.199 10.286  1   45.49  ? 200 ARG A CD  1 
ATOM   1646 N  NE  . ARG A 1 204 ? 5.524   -40.774 8.951   1   45.95  ? 200 ARG A NE  1 
ATOM   1647 C  CZ  . ARG A 1 204 ? 6.47    -41.141 8.092   1   45.3   ? 200 ARG A CZ  1 
ATOM   1648 N  NH1 . ARG A 1 204 ? 7.734   -41.094 8.456   1   46.52  ? 200 ARG A NH1 1 
ATOM   1649 N  NH2 . ARG A 1 204 ? 6.15    -41.573 6.88    1   45.08  ? 200 ARG A NH2 1 
ATOM   1650 N  N   . ALA A 1 205 ? 3.81    -35.51  10.716  1   25.83  ? 201 ALA A N   1 
ATOM   1651 C  CA  . ALA A 1 205 ? 3.348   -34.665 9.617   1   25.08  ? 201 ALA A CA  1 
ATOM   1652 C  C   . ALA A 1 205 ? 3.523   -35.391 8.279   1   26.38  ? 201 ALA A C   1 
ATOM   1653 O  O   . ALA A 1 205 ? 4.522   -36.064 8.062   1   26.44  ? 201 ALA A O   1 
ATOM   1654 C  CB  . ALA A 1 205 ? 4.08    -33.354 9.609   1   20.99  ? 201 ALA A CB  1 
ATOM   1655 N  N   . LEU A 1 206 ? 2.551   -35.25  7.373   1   24.63  ? 202 LEU A N   1 
ATOM   1656 C  CA  . LEU A 1 206 ? 2.66    -35.877 6.069   1   25.05  ? 202 LEU A CA  1 
ATOM   1657 C  C   . LEU A 1 206 ? 3.756   -35.246 5.197   1   26.17  ? 202 LEU A C   1 
ATOM   1658 O  O   . LEU A 1 206 ? 4.456   -35.963 4.496   1   32.04  ? 202 LEU A O   1 
ATOM   1659 C  CB  . LEU A 1 206 ? 1.298   -35.813 5.382   1   24.15  ? 202 LEU A CB  1 
ATOM   1660 C  CG  . LEU A 1 206 ? 1.184   -36.621 4.086   1   24.36  ? 202 LEU A CG  1 
ATOM   1661 C  CD1 . LEU A 1 206 ? 1.373   -38.113 4.354   1   20.14  ? 202 LEU A CD1 1 
ATOM   1662 C  CD2 . LEU A 1 206 ? -0.179  -36.356 3.499   1   24.52  ? 202 LEU A CD2 1 
ATOM   1663 N  N   . PHE A 1 207 ? 3.882   -33.914 5.177   1   23.79  ? 203 PHE A N   1 
ATOM   1664 C  CA  . PHE A 1 207 ? 4.881   -33.278 4.336   1   22.15  ? 203 PHE A CA  1 
ATOM   1665 C  C   . PHE A 1 207 ? 5.669   -32.267 5.159   1   23.24  ? 203 PHE A C   1 
ATOM   1666 O  O   . PHE A 1 207 ? 5.397   -31.066 5.108   1   32.49  ? 203 PHE A O   1 
ATOM   1667 C  CB  . PHE A 1 207 ? 4.173   -32.547 3.19    1   21.74  ? 203 PHE A CB  1 
ATOM   1668 C  CG  . PHE A 1 207 ? 3.215   -33.409 2.393   1   25.36  ? 203 PHE A CG  1 
ATOM   1669 C  CD1 . PHE A 1 207 ? 3.68    -34.515 1.679   1   25.96  ? 203 PHE A CD1 1 
ATOM   1670 C  CD2 . PHE A 1 207 ? 1.853   -33.116 2.35    1   30.82  ? 203 PHE A CD2 1 
ATOM   1671 C  CE1 . PHE A 1 207 ? 2.818   -35.285 0.921   1   24.86  ? 203 PHE A CE1 1 
ATOM   1672 C  CE2 . PHE A 1 207 ? 0.982   -33.906 1.601   1   30.28  ? 203 PHE A CE2 1 
ATOM   1673 C  CZ  . PHE A 1 207 ? 1.477   -34.984 0.879   1   27.11  ? 203 PHE A CZ  1 
ATOM   1674 N  N   . PRO A 1 208 ? 6.665   -32.67  5.971   1   21.81  ? 204 PRO A N   1 
ATOM   1675 C  CA  . PRO A 1 208 ? 7.347   -31.677 6.801   1   19.84  ? 204 PRO A CA  1 
ATOM   1676 C  C   . PRO A 1 208 ? 8.486   -30.985 6.054   1   21.63  ? 204 PRO A C   1 
ATOM   1677 O  O   . PRO A 1 208 ? 9.656   -31.302 6.253   1   22.52  ? 204 PRO A O   1 
ATOM   1678 C  CB  . PRO A 1 208 ? 7.835   -32.579 7.951   1   17.97  ? 204 PRO A CB  1 
ATOM   1679 C  CG  . PRO A 1 208 ? 8.204   -33.895 7.268   1   16.18  ? 204 PRO A CG  1 
ATOM   1680 C  CD  . PRO A 1 208 ? 7.157   -34.055 6.167   1   18.9   ? 204 PRO A CD  1 
ATOM   1681 N  N   . GLY A 1 209 ? 8.152   -30.036 5.185   1   23.85  ? 205 GLY A N   1 
ATOM   1682 C  CA  . GLY A 1 209 ? 9.173   -29.34  4.413   1   25.15  ? 205 GLY A CA  1 
ATOM   1683 C  C   . GLY A 1 209 ? 9.827   -28.247 5.246   1   28.55  ? 205 GLY A C   1 
ATOM   1684 O  O   . GLY A 1 209 ? 9.229   -27.785 6.213   1   28.73  ? 205 GLY A O   1 
ATOM   1685 N  N   . ASP A 1 210 ? 11.042  -27.836 4.86    1   35.76  ? 206 ASP A N   1 
ATOM   1686 C  CA  . ASP A 1 210 ? 11.767  -26.8   5.586   1   40.25  ? 206 ASP A CA  1 
ATOM   1687 C  C   . ASP A 1 210 ? 11.975  -25.577 4.701   1   35.97  ? 206 ASP A C   1 
ATOM   1688 O  O   . ASP A 1 210 ? 12.713  -24.684 5.084   1   44.78  ? 206 ASP A O   1 
ATOM   1689 C  CB  . ASP A 1 210 ? 12.961  -27.349 6.361   1   43.76  ? 206 ASP A CB  1 
ATOM   1690 C  CG  . ASP A 1 210 ? 14.039  -28.021 5.519   1   54.92  ? 206 ASP A CG  1 
ATOM   1691 O  OD1 . ASP A 1 210 ? 13.821  -28.133 4.291   1   71.34  ? 206 ASP A OD1 1 
ATOM   1692 O  OD2 . ASP A 1 210 ? 15.086  -28.45  6.09    1   43.79  ? 206 ASP A OD2 1 
ATOM   1693 N  N   . SER A 1 211 ? 11.295  -25.533 3.553   1   30.71  ? 207 SER A N   1 
ATOM   1694 C  CA  . SER A 1 211 ? 11.238  -24.36  2.69    1   29.56  ? 207 SER A CA  1 
ATOM   1695 C  C   . SER A 1 211 ? 10.034  -24.509 1.768   1   28.95  ? 207 SER A C   1 
ATOM   1696 O  O   . SER A 1 211 ? 9.435   -25.58  1.747   1   31.48  ? 207 SER A O   1 
ATOM   1697 C  CB  . SER A 1 211 ? 12.535  -24.158 1.912   1   29.64  ? 207 SER A CB  1 
ATOM   1698 O  OG  . SER A 1 211 ? 12.844  -25.266 1.084   1   30.27  ? 207 SER A OG  1 
ATOM   1699 N  N   . GLU A 1 212 ? 9.684   -23.517 0.968   1   28.87  ? 208 GLU A N   1 
ATOM   1700 C  CA  . GLU A 1 212 ? 8.536   -23.733 0.054   1   30.15  ? 208 GLU A CA  1 
ATOM   1701 C  C   . GLU A 1 212 ? 8.872   -24.776 -1.019  1   27.1   ? 208 GLU A C   1 
ATOM   1702 O  O   . GLU A 1 212 ? 7.955   -25.49  -1.435  1   25.68  ? 208 GLU A O   1 
ATOM   1703 C  CB  . GLU A 1 212 ? 8.126   -22.435 -0.636  1   34.31  ? 208 GLU A CB  1 
ATOM   1704 C  CG  . GLU A 1 212 ? 7.592   -21.358 0.299   1   46.21  ? 208 GLU A CG  1 
ATOM   1705 C  CD  . GLU A 1 212 ? 7.408   -20.042 -0.434  1   55.27  ? 208 GLU A CD  1 
ATOM   1706 O  OE1 . GLU A 1 212 ? 6.437   -19.917 -1.205  1   52.64  ? 208 GLU A OE1 1 
ATOM   1707 O  OE2 . GLU A 1 212 ? 8.249   -19.143 -0.242  1   69.42  ? 208 GLU A OE2 1 
ATOM   1708 N  N   . ILE A 1 213 ? 10.128  -24.853 -1.447  1   26.17  ? 209 ILE A N   1 
ATOM   1709 C  CA  . ILE A 1 213 ? 10.524  -25.768 -2.56   1   26.7   ? 209 ILE A CA  1 
ATOM   1710 C  C   . ILE A 1 213 ? 10.695  -27.188 -2.008  1   25.66  ? 209 ILE A C   1 
ATOM   1711 O  O   . ILE A 1 213 ? 10.327  -28.134 -2.706  1   24.2   ? 209 ILE A O   1 
ATOM   1712 C  CB  . ILE A 1 213 ? 11.78   -25.231 -3.276  1   27.1   ? 209 ILE A CB  1 
ATOM   1713 C  CG1 . ILE A 1 213 ? 11.539  -23.825 -3.794  1   32.83  ? 209 ILE A CG1 1 
ATOM   1714 C  CG2 . ILE A 1 213 ? 12.254  -26.161 -4.389  1   25.79  ? 209 ILE A CG2 1 
ATOM   1715 C  CD1 . ILE A 1 213 ? 10.383  -23.722 -4.769  1   33.74  ? 209 ILE A CD1 1 
ATOM   1716 N  N   . ASP A 1 214 ? 11.195  -27.306 -0.787  1   27.02  ? 210 ASP A N   1 
ATOM   1717 C  CA  . ASP A 1 214 ? 11.324  -28.637 -0.153  1   26.12  ? 210 ASP A CA  1 
ATOM   1718 C  C   . ASP A 1 214 ? 9.912   -29.153 0.071   1   26.06  ? 210 ASP A C   1 
ATOM   1719 O  O   . ASP A 1 214 ? 9.69    -30.358 -0.079  1   30.6   ? 210 ASP A O   1 
ATOM   1720 C  CB  . ASP A 1 214 ? 12.144  -28.577 1.124   1   29.3   ? 210 ASP A CB  1 
ATOM   1721 C  CG  . ASP A 1 214 ? 12.356  -29.904 1.831   1   34.47  ? 210 ASP A CG  1 
ATOM   1722 O  OD1 . ASP A 1 214 ? 12.839  -30.846 1.177   1   37.39  ? 210 ASP A OD1 1 
ATOM   1723 O  OD2 . ASP A 1 214 ? 12.034  -29.977 3.026   1   31.89  ? 210 ASP A OD2 1 
ATOM   1724 N  N   . GLN A 1 215 ? 9.008   -28.244 0.405   1   24.36  ? 211 GLN A N   1 
ATOM   1725 C  CA  . GLN A 1 215 ? 7.639   -28.645 0.664   1   22.44  ? 211 GLN A CA  1 
ATOM   1726 C  C   . GLN A 1 215 ? 7.008   -29.194 -0.612  1   22.8   ? 211 GLN A C   1 
ATOM   1727 O  O   . GLN A 1 215 ? 6.383   -30.249 -0.56   1   25.74  ? 211 GLN A O   1 
ATOM   1728 C  CB  . GLN A 1 215 ? 6.816   -27.448 1.135   1   21.79  ? 211 GLN A CB  1 
ATOM   1729 C  CG  . GLN A 1 215 ? 5.376   -27.809 1.479   1   20.83  ? 211 GLN A CG  1 
ATOM   1730 C  CD  . GLN A 1 215 ? 5.367   -28.545 2.792   1   21.72  ? 211 GLN A CD  1 
ATOM   1731 O  OE1 . GLN A 1 215 ? 6.345   -28.485 3.545   1   23.43  ? 211 GLN A OE1 1 
ATOM   1732 N  NE2 . GLN A 1 215 ? 4.283   -29.239 3.075   1   19.63  ? 211 GLN A NE2 1 
ATOM   1733 N  N   . LEU A 1 216 ? 7.215   -28.383 -1.713  1   20.97  ? 212 LEU A N   1 
ATOM   1734 C  CA  . LEU A 1 216 ? 6.681   -28.773 -3.039  1   23.08  ? 212 LEU A CA  1 
ATOM   1735 C  C   . LEU A 1 216 ? 7.228   -30.154 -3.41   1   25.34  ? 212 LEU A C   1 
ATOM   1736 O  O   . LEU A 1 216 ? 6.43    -31.02  -3.827  1   26.54  ? 212 LEU A O   1 
ATOM   1737 C  CB  . LEU A 1 216 ? 7.14    -27.708 -4.029  1   26.48  ? 212 LEU A CB  1 
ATOM   1738 C  CG  . LEU A 1 216 ? 6.309   -27.568 -5.305  1   28.92  ? 212 LEU A CG  1 
ATOM   1739 C  CD1 . LEU A 1 216 ? 4.839   -27.385 -4.968  1   30.75  ? 212 LEU A CD1 1 
ATOM   1740 C  CD2 . LEU A 1 216 ? 6.833   -26.383 -6.088  1   23.32  ? 212 LEU A CD2 1 
ATOM   1741 N  N   . PHE A 1 217 ? 8.495   -30.376 -3.236  1   23.38  ? 213 PHE A N   1 
ATOM   1742 C  CA  . PHE A 1 217 ? 9.154   -31.637 -3.676  1   22.63  ? 213 PHE A CA  1 
ATOM   1743 C  C   . PHE A 1 217 ? 8.674   -32.785 -2.794  1   26.16  ? 213 PHE A C   1 
ATOM   1744 O  O   . PHE A 1 217 ? 8.384   -33.871 -3.331  1   32.7   ? 213 PHE A O   1 
ATOM   1745 C  CB  . PHE A 1 217 ? 10.668  -31.406 -3.693  1   20.22  ? 213 PHE A CB  1 
ATOM   1746 C  CG  . PHE A 1 217 ? 11.096  -30.496 -4.836  1   17.9   ? 213 PHE A CG  1 
ATOM   1747 C  CD1 . PHE A 1 217 ? 10.256  -30.277 -5.923  1   15.7   ? 213 PHE A CD1 1 
ATOM   1748 C  CD2 . PHE A 1 217 ? 12.33   -29.857 -4.821  1   16.41  ? 213 PHE A CD2 1 
ATOM   1749 C  CE1 . PHE A 1 217 ? 10.64   -29.447 -6.963  1   14.97  ? 213 PHE A CE1 1 
ATOM   1750 C  CE2 . PHE A 1 217 ? 12.71   -29.029 -5.866  1   15.83  ? 213 PHE A CE2 1 
ATOM   1751 C  CZ  . PHE A 1 217 ? 11.866  -28.826 -6.933  1   14.82  ? 213 PHE A CZ  1 
ATOM   1752 N  N   . ARG A 1 218 ? 8.579   -32.578 -1.489  1   24.91  ? 214 ARG A N   1 
ATOM   1753 C  CA  . ARG A 1 218 ? 8.038   -33.638 -0.606  1   25.77  ? 214 ARG A CA  1 
ATOM   1754 C  C   . ARG A 1 218 ? 6.638   -34.048 -1.084  1   25.51  ? 214 ARG A C   1 
ATOM   1755 O  O   . ARG A 1 218 ? 6.323   -35.239 -1.024  1   27.93  ? 214 ARG A O   1 
ATOM   1756 C  CB  . ARG A 1 218 ? 8.031   -33.154 0.841   1   24.93  ? 214 ARG A CB  1 
ATOM   1757 C  CG  . ARG A 1 218 ? 9.24    -33.536 1.674   1   27.41  ? 214 ARG A CG  1 
ATOM   1758 C  CD  . ARG A 1 218 ? 9.472   -32.489 2.737   1   29.93  ? 214 ARG A CD  1 
ATOM   1759 N  NE  . ARG A 1 218 ? 10.845  -32.535 3.245   1   26.61  ? 214 ARG A NE  1 
ATOM   1760 C  CZ  . ARG A 1 218 ? 11.216  -33.207 4.319   1   25.6   ? 214 ARG A CZ  1 
ATOM   1761 N  NH1 . ARG A 1 218 ? 10.614  -34.336 4.639   1   26.88  ? 214 ARG A NH1 1 
ATOM   1762 N  NH2 . ARG A 1 218 ? 12.186  -32.74  5.078   1   23.03  ? 214 ARG A NH2 1 
ATOM   1763 N  N   . ILE A 1 219 ? 5.849   -33.089 -1.558  1   24.75  ? 215 ILE A N   1 
ATOM   1764 C  CA  . ILE A 1 219 ? 4.528   -33.419 -2.047  1   23.35  ? 215 ILE A CA  1 
ATOM   1765 C  C   . ILE A 1 219 ? 4.677   -34.194 -3.354  1   23.53  ? 215 ILE A C   1 
ATOM   1766 O  O   . ILE A 1 219 ? 4.128   -35.277 -3.473  1   25.81  ? 215 ILE A O   1 
ATOM   1767 C  CB  . ILE A 1 219 ? 3.664   -32.161 -2.191  1   23.37  ? 215 ILE A CB  1 
ATOM   1768 C  CG1 . ILE A 1 219 ? 3.41    -31.531 -0.812  1   24.11  ? 215 ILE A CG1 1 
ATOM   1769 C  CG2 . ILE A 1 219 ? 2.347   -32.53  -2.875  1   21.74  ? 215 ILE A CG2 1 
ATOM   1770 C  CD1 . ILE A 1 219 ? 2.845   -30.112 -0.835  1   22.81  ? 215 ILE A CD1 1 
ATOM   1771 N  N   . PHE A 1 220 ? 5.457   -33.666 -4.304  1   22.78  ? 216 PHE A N   1 
ATOM   1772 C  CA  . PHE A 1 220 ? 5.702   -34.33  -5.577  1   21.88  ? 216 PHE A CA  1 
ATOM   1773 C  C   . PHE A 1 220 ? 6.246   -35.749 -5.378  1   21.81  ? 216 PHE A C   1 
ATOM   1774 O  O   . PHE A 1 220 ? 5.854   -36.675 -6.079  1   21.39  ? 216 PHE A O   1 
ATOM   1775 C  CB  . PHE A 1 220 ? 6.689   -33.55  -6.44   1   19.8   ? 216 PHE A CB  1 
ATOM   1776 C  CG  . PHE A 1 220 ? 6.202   -32.222 -6.993  1   18.43  ? 216 PHE A CG  1 
ATOM   1777 C  CD1 . PHE A 1 220 ? 4.932   -31.739 -6.696  1   16.56  ? 216 PHE A CD1 1 
ATOM   1778 C  CD2 . PHE A 1 220 ? 7.053   -31.451 -7.795  1   18.17  ? 216 PHE A CD2 1 
ATOM   1779 C  CE1 . PHE A 1 220 ? 4.508   -30.527 -7.203  1   15.65  ? 216 PHE A CE1 1 
ATOM   1780 C  CE2 . PHE A 1 220 ? 6.622   -30.236 -8.313  1   18.03  ? 216 PHE A CE2 1 
ATOM   1781 C  CZ  . PHE A 1 220 ? 5.358   -29.769 -7.997  1   17.11  ? 216 PHE A CZ  1 
ATOM   1782 N  N   . ARG A 1 221 ? 7.147   -35.919 -4.408  1   23.07  ? 217 ARG A N   1 
ATOM   1783 C  CA  . ARG A 1 221 ? 7.763   -37.253 -4.174  1   20.19  ? 217 ARG A CA  1 
ATOM   1784 C  C   . ARG A 1 221 ? 6.71    -38.23  -3.631  1   21.17  ? 217 ARG A C   1 
ATOM   1785 O  O   . ARG A 1 221 ? 6.925   -39.455 -3.755  1   24.56  ? 217 ARG A O   1 
ATOM   1786 C  CB  . ARG A 1 221 ? 8.918   -37.143 -3.174  1   18.8   ? 217 ARG A CB  1 
ATOM   1787 C  CG  . ARG A 1 221 ? 10.189  -36.567 -3.778  1   19.67  ? 217 ARG A CG  1 
ATOM   1788 C  CD  . ARG A 1 221 ? 11.25   -36.288 -2.73   1   22.6   ? 217 ARG A CD  1 
ATOM   1789 N  NE  . ARG A 1 221 ? 10.917  -35.131 -1.893  1   27.19  ? 217 ARG A NE  1 
ATOM   1790 C  CZ  . ARG A 1 221 ? 11.745  -34.122 -1.657  1   26.59  ? 217 ARG A CZ  1 
ATOM   1791 N  NH1 . ARG A 1 221 ? 11.586  -33.367 -0.584  1   26.42  ? 217 ARG A NH1 1 
ATOM   1792 N  NH2 . ARG A 1 221 ? 12.73   -33.871 -2.5    1   22.52  ? 217 ARG A NH2 1 
ATOM   1793 N  N   . THR A 1 222 ? 5.62    -37.714 -3.06   1   22.21  ? 218 THR A N   1 
ATOM   1794 C  CA  . THR A 1 222 ? 4.6     -38.567 -2.447  1   23.44  ? 218 THR A CA  1 
ATOM   1795 C  C   . THR A 1 222 ? 3.417   -38.83  -3.383  1   25.58  ? 218 THR A C   1 
ATOM   1796 O  O   . THR A 1 222 ? 2.885   -39.926 -3.388  1   31.69  ? 218 THR A O   1 
ATOM   1797 C  CB  . THR A 1 222 ? 4.097   -37.949 -1.14   1   25.49  ? 218 THR A CB  1 
ATOM   1798 O  OG1 . THR A 1 222 ? 5.21    -37.871 -0.253  1   24.47  ? 218 THR A OG1 1 
ATOM   1799 C  CG2 . THR A 1 222 ? 2.959   -38.741 -0.517  1   26.88  ? 218 THR A CG2 1 
ATOM   1800 N  N   . LEU A 1 223 ? 2.979   -37.834 -4.155  1   23.57  ? 219 LEU A N   1 
ATOM   1801 C  CA  . LEU A 1 223 ? 1.789   -37.968 -4.971  1   25.03  ? 219 LEU A CA  1 
ATOM   1802 C  C   . LEU A 1 223 ? 2.17    -37.889 -6.45   1   27.96  ? 219 LEU A C   1 
ATOM   1803 O  O   . LEU A 1 223 ? 1.302   -37.799 -7.324  1   30.3   ? 219 LEU A O   1 
ATOM   1804 C  CB  . LEU A 1 223 ? 0.879   -36.8   -4.589  1   26.1   ? 219 LEU A CB  1 
ATOM   1805 C  CG  . LEU A 1 223 ? 0.531   -36.686 -3.103  1   24.52  ? 219 LEU A CG  1 
ATOM   1806 C  CD1 . LEU A 1 223 ? -0.402  -35.526 -2.863  1   21.6   ? 219 LEU A CD1 1 
ATOM   1807 C  CD2 . LEU A 1 223 ? -0.121  -37.996 -2.66   1   24     ? 219 LEU A CD2 1 
ATOM   1808 N  N   . GLY A 1 224 ? 3.481   -37.876 -6.71   1   25.18  ? 220 GLY A N   1 
ATOM   1809 C  CA  . GLY A 1 224 ? 4.013   -37.726 -8.053  1   21.63  ? 220 GLY A CA  1 
ATOM   1810 C  C   . GLY A 1 224 ? 4.02    -36.26  -8.459  1   20.26  ? 220 GLY A C   1 
ATOM   1811 O  O   . GLY A 1 224 ? 3.22    -35.474 -7.958  1   19.23  ? 220 GLY A O   1 
ATOM   1812 N  N   . THR A 1 225 ? 4.944   -35.913 -9.357  1   20.19  ? 221 THR A N   1 
ATOM   1813 C  CA  . THR A 1 225 ? 5.031   -34.56  -9.877  1   21.89  ? 221 THR A CA  1 
ATOM   1814 C  C   . THR A 1 225 ? 3.848   -34.376 -10.817 1   24.01  ? 221 THR A C   1 
ATOM   1815 O  O   . THR A 1 225 ? 3.685   -35.112 -11.771 1   30.02  ? 221 THR A O   1 
ATOM   1816 C  CB  . THR A 1 225 ? 6.347   -34.322 -10.626 1   21.12  ? 221 THR A CB  1 
ATOM   1817 O  OG1 . THR A 1 225 ? 7.495   -34.649 -9.842  1   19.94  ? 221 THR A OG1 1 
ATOM   1818 C  CG2 . THR A 1 225 ? 6.428   -32.901 -11.147 1   19.04  ? 221 THR A CG2 1 
ATOM   1819 N  N   . PRO A 1 226 ? 2.974   -33.388 -10.611 1   25.16  ? 222 PRO A N   1 
ATOM   1820 C  CA  . PRO A 1 226 ? 1.778   -33.273 -11.454 1   25.14  ? 222 PRO A CA  1 
ATOM   1821 C  C   . PRO A 1 226 ? 2.13    -32.792 -12.863 1   26     ? 222 PRO A C   1 
ATOM   1822 O  O   . PRO A 1 226 ? 3.134   -32.101 -13.056 1   26.41  ? 222 PRO A O   1 
ATOM   1823 C  CB  . PRO A 1 226 ? 0.936   -32.232 -10.669 1   25.01  ? 222 PRO A CB  1 
ATOM   1824 C  CG  . PRO A 1 226 ? 2.005   -31.356 -9.995  1   23.96  ? 222 PRO A CG  1 
ATOM   1825 C  CD  . PRO A 1 226 ? 3.114   -32.327 -9.597  1   24.48  ? 222 PRO A CD  1 
ATOM   1826 N  N   . ASP A 1 227 ? 1.291   -33.159 -13.843 1   26.78  ? 223 ASP A N   1 
ATOM   1827 C  CA  . ASP A 1 227 ? 1.434   -32.671 -15.21  1   29.5   ? 223 ASP A CA  1 
ATOM   1828 C  C   . ASP A 1 227 ? 0.051   -32.227 -15.68  1   29.51  ? 223 ASP A C   1 
ATOM   1829 O  O   . ASP A 1 227 ? -0.887  -32.209 -14.884 1   30.24  ? 223 ASP A O   1 
ATOM   1830 C  CB  . ASP A 1 227 ? 1.988   -33.754 -16.113 1   27.99  ? 223 ASP A CB  1 
ATOM   1831 C  CG  . ASP A 1 227 ? 1.012   -34.91  -16.165 1   35.54  ? 223 ASP A CG  1 
ATOM   1832 O  OD1 . ASP A 1 227 ? -0.156  -34.695 -15.82  1   39.25  ? 223 ASP A OD1 1 
ATOM   1833 O  OD2 . ASP A 1 227 ? 1.416   -36.005 -16.521 1   44.28  ? 223 ASP A OD2 1 
ATOM   1834 N  N   . GLU A 1 228 ? -0.078  -31.916 -16.974 1   31.41  ? 224 GLU A N   1 
ATOM   1835 C  CA  . GLU A 1 228 ? -1.26   -31.229 -17.49  1   33.12  ? 224 GLU A CA  1 
ATOM   1836 C  C   . GLU A 1 228 ? -2.48   -32.149 -17.419 1   34.36  ? 224 GLU A C   1 
ATOM   1837 O  O   . GLU A 1 228 ? -3.624  -31.68  -17.3   1   35.59  ? 224 GLU A O   1 
ATOM   1838 C  CB  . GLU A 1 228 ? -0.993  -30.641 -18.88  1   30.14  ? 224 GLU A CB  1 
ATOM   1839 C  CG  . GLU A 1 228 ? -0.148  -29.367 -18.848 1   31.09  ? 224 GLU A CG  1 
ATOM   1840 C  CD  . GLU A 1 228 ? -0.917  -28.157 -18.319 1   38.51  ? 224 GLU A CD  1 
ATOM   1841 O  OE1 . GLU A 1 228 ? -2.175  -28.143 -18.406 1   37.5   ? 224 GLU A OE1 1 
ATOM   1842 O  OE2 . GLU A 1 228 ? -0.277  -27.23  -17.766 1   38.66  ? 224 GLU A OE2 1 
ATOM   1843 N  N   . VAL A 1 229 ? -2.199  -33.461 -17.433 1   31.52  ? 225 VAL A N   1 
ATOM   1844 C  CA  . VAL A 1 229 ? -3.212  -34.501 -17.418 1   30.75  ? 225 VAL A CA  1 
ATOM   1845 C  C   . VAL A 1 229 ? -3.86   -34.542 -16.037 1   31.28  ? 225 VAL A C   1 
ATOM   1846 O  O   . VAL A 1 229 ? -5.067  -34.432 -15.919 1   34.8   ? 225 VAL A O   1 
ATOM   1847 C  CB  . VAL A 1 229 ? -2.596  -35.868 -17.754 1   31.31  ? 225 VAL A CB  1 
ATOM   1848 C  CG1 . VAL A 1 229 ? -3.647  -36.97  -17.703 1   29.29  ? 225 VAL A CG1 1 
ATOM   1849 C  CG2 . VAL A 1 229 ? -1.815  -35.848 -19.071 1   29.99  ? 225 VAL A CG2 1 
ATOM   1850 N  N   . VAL A 1 230 ? -3.063  -34.736 -14.99  1   28.59  ? 226 VAL A N   1 
ATOM   1851 C  CA  . VAL A 1 230 ? -3.646  -34.732 -13.668 1   30.94  ? 226 VAL A CA  1 
ATOM   1852 C  C   . VAL A 1 230 ? -4.08   -33.314 -13.27  1   27.53  ? 226 VAL A C   1 
ATOM   1853 O  O   . VAL A 1 230 ? -5.077  -33.143 -12.582 1   29.05  ? 226 VAL A O   1 
ATOM   1854 C  CB  . VAL A 1 230 ? -2.716  -35.424 -12.652 1   34.35  ? 226 VAL A CB  1 
ATOM   1855 C  CG1 . VAL A 1 230 ? -1.392  -34.706 -12.583 1   38.96  ? 226 VAL A CG1 1 
ATOM   1856 C  CG2 . VAL A 1 230 ? -3.337  -35.5   -11.259 1   38.66  ? 226 VAL A CG2 1 
ATOM   1857 N  N   . TRP A 1 231 ? -3.381  -32.272 -13.711 1   27.86  ? 227 TRP A N   1 
ATOM   1858 C  CA  . TRP A 1 231 ? -3.757  -30.948 -13.231 1   30.14  ? 227 TRP A CA  1 
ATOM   1859 C  C   . TRP A 1 231 ? -3.711  -29.912 -14.352 1   31.27  ? 227 TRP A C   1 
ATOM   1860 O  O   . TRP A 1 231 ? -2.713  -29.221 -14.532 1   33.92  ? 227 TRP A O   1 
ATOM   1861 C  CB  . TRP A 1 231 ? -2.85   -30.565 -12.055 1   29.32  ? 227 TRP A CB  1 
ATOM   1862 C  CG  . TRP A 1 231 ? -3.164  -29.256 -11.39  1   32.23  ? 227 TRP A CG  1 
ATOM   1863 C  CD1 . TRP A 1 231 ? -4.192  -28.402 -11.656 1   30.1   ? 227 TRP A CD1 1 
ATOM   1864 C  CD2 . TRP A 1 231 ? -2.417  -28.669 -10.3   1   32.81  ? 227 TRP A CD2 1 
ATOM   1865 N  NE1 . TRP A 1 231 ? -4.14   -27.334 -10.802 1   30.36  ? 227 TRP A NE1 1 
ATOM   1866 C  CE2 . TRP A 1 231 ? -3.065  -27.464 -9.964  1   30.34  ? 227 TRP A CE2 1 
ATOM   1867 C  CE3 . TRP A 1 231 ? -1.272  -29.047 -9.592  1   30.7   ? 227 TRP A CE3 1 
ATOM   1868 C  CZ2 . TRP A 1 231 ? -2.607  -26.631 -8.947  1   31.31  ? 227 TRP A CZ2 1 
ATOM   1869 C  CZ3 . TRP A 1 231 ? -0.802  -28.218 -8.606  1   34.12  ? 227 TRP A CZ3 1 
ATOM   1870 C  CH2 . TRP A 1 231 ? -1.474  -27.034 -8.277  1   35.07  ? 227 TRP A CH2 1 
ATOM   1871 N  N   . PRO A 1 232 ? -4.783  -29.743 -15.152 1   33.82  ? 228 PRO A N   1 
ATOM   1872 C  CA  . PRO A 1 232 ? -4.757  -28.728 -16.215 1   33.5   ? 228 PRO A CA  1 
ATOM   1873 C  C   . PRO A 1 232 ? -4.41   -27.342 -15.65  1   35.23  ? 228 PRO A C   1 
ATOM   1874 O  O   . PRO A 1 232 ? -5.034  -26.891 -14.687 1   32.21  ? 228 PRO A O   1 
ATOM   1875 C  CB  . PRO A 1 232 ? -6.141  -28.786 -16.897 1   29.63  ? 228 PRO A CB  1 
ATOM   1876 C  CG  . PRO A 1 232 ? -6.762  -30.061 -16.365 1   31.52  ? 228 PRO A CG  1 
ATOM   1877 C  CD  . PRO A 1 232 ? -6.032  -30.519 -15.098 1   31.27  ? 228 PRO A CD  1 
ATOM   1878 N  N   . GLY A 1 233 ? -3.402  -26.677 -16.251 1   36.26  ? 229 GLY A N   1 
ATOM   1879 C  CA  . GLY A 1 233 ? -2.99   -25.352 -15.81  1   34.25  ? 229 GLY A CA  1 
ATOM   1880 C  C   . GLY A 1 233 ? -1.653  -25.366 -15.073 1   36.22  ? 229 GLY A C   1 
ATOM   1881 O  O   . GLY A 1 233 ? -0.916  -24.381 -15.12  1   39.28  ? 229 GLY A O   1 
ATOM   1882 N  N   . VAL A 1 234 ? -1.331  -26.499 -14.433 1   33.59  ? 230 VAL A N   1 
ATOM   1883 C  CA  . VAL A 1 234 ? -0.237  -26.588 -13.481 1   30.81  ? 230 VAL A CA  1 
ATOM   1884 C  C   . VAL A 1 234 ? 1.029   -25.99  -14.089 1   32.22  ? 230 VAL A C   1 
ATOM   1885 O  O   . VAL A 1 234 ? 1.716   -25.228 -13.406 1   31.31  ? 230 VAL A O   1 
ATOM   1886 C  CB  . VAL A 1 234 ? 0.01    -27.984 -12.878 1   26.98  ? 230 VAL A CB  1 
ATOM   1887 C  CG1 . VAL A 1 234 ? 0.572   -28.966 -13.889 1   26.93  ? 230 VAL A CG1 1 
ATOM   1888 C  CG2 . VAL A 1 234 ? 0.946   -27.904 -11.697 1   23.84  ? 230 VAL A CG2 1 
ATOM   1889 N  N   . THR A 1 235 ? 1.296   -26.294 -15.371 1   30.29  ? 231 THR A N   1 
ATOM   1890 C  CA  . THR A 1 235 ? 2.573   -25.921 -15.97  1   30.17  ? 231 THR A CA  1 
ATOM   1891 C  C   . THR A 1 235 ? 2.594   -24.436 -16.318 1   31.05  ? 231 THR A C   1 
ATOM   1892 O  O   . THR A 1 235 ? 3.641   -23.941 -16.722 1   38     ? 231 THR A O   1 
ATOM   1893 C  CB  . THR A 1 235 ? 2.991   -26.734 -17.198 1   27.87  ? 231 THR A CB  1 
ATOM   1894 O  OG1 . THR A 1 235 ? 2.035   -26.41  -18.195 1   30.99  ? 231 THR A OG1 1 
ATOM   1895 C  CG2 . THR A 1 235 ? 3.073   -28.231 -16.98  1   25.37  ? 231 THR A CG2 1 
ATOM   1896 N  N   . SER A 1 236 ? 1.455   -23.746 -16.199 1   31.85  ? 232 SER A N   1 
ATOM   1897 C  CA  . SER A 1 236 ? 1.365   -22.33  -16.548 1   36.9   ? 232 SER A CA  1 
ATOM   1898 C  C   . SER A 1 236 ? 1.47    -21.489 -15.283 1   40.29  ? 232 SER A C   1 
ATOM   1899 O  O   . SER A 1 236 ? 1.367   -20.264 -15.315 1   37.28  ? 232 SER A O   1 
ATOM   1900 C  CB  . SER A 1 236 ? 0.055   -22.011 -17.248 1   38.01  ? 232 SER A CB  1 
ATOM   1901 O  OG  . SER A 1 236 ? 0.151   -22.343 -18.624 1   46.8   ? 232 SER A OG  1 
ATOM   1902 N  N   . MET A 1 237 ? 1.602   -22.172 -14.147 1   40.9   ? 233 MET A N   1 
ATOM   1903 C  CA  . MET A 1 237 ? 1.443   -21.474 -12.886 1   38.19  ? 233 MET A CA  1 
ATOM   1904 C  C   . MET A 1 237 ? 2.687   -20.67  -12.57  1   32.82  ? 233 MET A C   1 
ATOM   1905 O  O   . MET A 1 237 ? 3.791   -21.095 -12.917 1   32     ? 233 MET A O   1 
ATOM   1906 C  CB  . MET A 1 237 ? 1.029   -22.437 -11.784 1   37.52  ? 233 MET A CB  1 
ATOM   1907 C  CG  . MET A 1 237 ? -0.389  -22.746 -12.049 1   43.08  ? 233 MET A CG  1 
ATOM   1908 S  SD  . MET A 1 237 ? -1.026  -23.881 -10.829 1   54.79  ? 233 MET A SD  1 
ATOM   1909 C  CE  . MET A 1 237 ? -1.833  -22.621 -9.822  1   30.82  ? 233 MET A CE  1 
ATOM   1910 N  N   . PRO A 1 238 ? 2.519   -19.496 -11.918 1   28.8   ? 234 PRO A N   1 
ATOM   1911 C  CA  . PRO A 1 238 ? 3.578   -18.479 -11.908 1   25.3   ? 234 PRO A CA  1 
ATOM   1912 C  C   . PRO A 1 238 ? 4.925   -18.985 -11.388 1   25.32  ? 234 PRO A C   1 
ATOM   1913 O  O   . PRO A 1 238 ? 5.966   -18.635 -11.949 1   29.56  ? 234 PRO A O   1 
ATOM   1914 C  CB  . PRO A 1 238 ? 2.992   -17.331 -11.074 1   22.3   ? 234 PRO A CB  1 
ATOM   1915 C  CG  . PRO A 1 238 ? 1.5     -17.595 -11.046 1   22.61  ? 234 PRO A CG  1 
ATOM   1916 C  CD  . PRO A 1 238 ? 1.342   -19.12  -11.104 1   24.65  ? 234 PRO A CD  1 
ATOM   1917 N  N   . ASP A 1 239 ? 4.887   -19.872 -10.382 1   23.69  ? 235 ASP A N   1 
ATOM   1918 C  CA  . ASP A 1 239 ? 6.094   -20.425 -9.806  1   24.59  ? 235 ASP A CA  1 
ATOM   1919 C  C   . ASP A 1 239 ? 6.31    -21.879 -10.193 1   27.5   ? 235 ASP A C   1 
ATOM   1920 O  O   . ASP A 1 239 ? 7.163   -22.529 -9.577  1   31.34  ? 235 ASP A O   1 
ATOM   1921 C  CB  . ASP A 1 239 ? 6.14    -20.196 -8.31   1   25.35  ? 235 ASP A CB  1 
ATOM   1922 C  CG  . ASP A 1 239 ? 6.151   -18.724 -7.97   1   26.23  ? 235 ASP A CG  1 
ATOM   1923 O  OD1 . ASP A 1 239 ? 6.65    -17.951 -8.801  1   28.22  ? 235 ASP A OD1 1 
ATOM   1924 O  OD2 . ASP A 1 239 ? 5.568   -18.369 -6.944  1   30.19  ? 235 ASP A OD2 1 
ATOM   1925 N  N   . TYR A 1 240 ? 5.597   -22.358 -11.227 1   27.43  ? 236 TYR A N   1 
ATOM   1926 C  CA  . TYR A 1 240 ? 5.88    -23.662 -11.809 1   28.4   ? 236 TYR A CA  1 
ATOM   1927 C  C   . TYR A 1 240 ? 7.081   -23.532 -12.735 1   28.08  ? 236 TYR A C   1 
ATOM   1928 O  O   . TYR A 1 240 ? 7.097   -22.633 -13.573 1   30.01  ? 236 TYR A O   1 
ATOM   1929 C  CB  . TYR A 1 240 ? 4.744   -24.226 -12.673 1   32.35  ? 236 TYR A CB  1 
ATOM   1930 C  CG  . TYR A 1 240 ? 5.131   -25.521 -13.384 1   36.22  ? 236 TYR A CG  1 
ATOM   1931 C  CD1 . TYR A 1 240 ? 5.069   -26.758 -12.741 1   38.18  ? 236 TYR A CD1 1 
ATOM   1932 C  CD2 . TYR A 1 240 ? 5.61    -25.495 -14.691 1   37.9   ? 236 TYR A CD2 1 
ATOM   1933 C  CE1 . TYR A 1 240 ? 5.451   -27.927 -13.388 1   41.6   ? 236 TYR A CE1 1 
ATOM   1934 C  CE2 . TYR A 1 240 ? 5.998   -26.652 -15.343 1   41.46  ? 236 TYR A CE2 1 
ATOM   1935 C  CZ  . TYR A 1 240 ? 5.924   -27.869 -14.691 1   43.11  ? 236 TYR A CZ  1 
ATOM   1936 O  OH  . TYR A 1 240 ? 6.316   -28.969 -15.407 1   45.26  ? 236 TYR A OH  1 
ATOM   1937 N  N   . LYS A 1 241 ? 8.03    -24.474 -12.624 1   27.74  ? 237 LYS A N   1 
ATOM   1938 C  CA  . LYS A 1 241 ? 9.219   -24.486 -13.463 1   28.33  ? 237 LYS A CA  1 
ATOM   1939 C  C   . LYS A 1 241 ? 9.315   -25.812 -14.209 1   27.01  ? 237 LYS A C   1 
ATOM   1940 O  O   . LYS A 1 241 ? 9.165   -26.869 -13.596 1   24.73  ? 237 LYS A O   1 
ATOM   1941 C  CB  . LYS A 1 241 ? 10.477  -24.252 -12.619 1   28.99  ? 237 LYS A CB  1 
ATOM   1942 C  CG  . LYS A 1 241 ? 10.421  -22.955 -11.819 1   32.39  ? 237 LYS A CG  1 
ATOM   1943 C  CD  . LYS A 1 241 ? 11.488  -22.865 -10.737 1   39.09  ? 237 LYS A CD  1 
ATOM   1944 C  CE  . LYS A 1 241 ? 12.856  -22.828 -11.336 1   47.17  ? 237 LYS A CE  1 
ATOM   1945 N  NZ  . LYS A 1 241 ? 13.084  -21.67  -12.213 1   54.64  ? 237 LYS A NZ  1 
ATOM   1946 N  N   . PRO A 1 242 ? 9.575   -25.781 -15.544 1   25.61  ? 238 PRO A N   1 
ATOM   1947 C  CA  . PRO A 1 242 ? 9.778   -26.988 -16.355 1   23.68  ? 238 PRO A CA  1 
ATOM   1948 C  C   . PRO A 1 242 ? 10.84   -27.953 -15.832 1   22.68  ? 238 PRO A C   1 
ATOM   1949 O  O   . PRO A 1 242 ? 10.768  -29.15  -16.081 1   23.57  ? 238 PRO A O   1 
ATOM   1950 C  CB  . PRO A 1 242 ? 10.155  -26.497 -17.772 1   23.23  ? 238 PRO A CB  1 
ATOM   1951 C  CG  . PRO A 1 242 ? 9.998   -24.994 -17.762 1   23.14  ? 238 PRO A CG  1 
ATOM   1952 C  CD  . PRO A 1 242 ? 9.661   -24.557 -16.344 1   24.73  ? 238 PRO A CD  1 
ATOM   1953 N  N   . SER A 1 243 ? 11.845  -27.415 -15.128 1   21.69  ? 239 SER A N   1 
ATOM   1954 C  CA  . SER A 1 243 ? 12.978  -28.181 -14.613 1   20.11  ? 239 SER A CA  1 
ATOM   1955 C  C   . SER A 1 243 ? 12.625  -28.997 -13.359 1   18.46  ? 239 SER A C   1 
ATOM   1956 O  O   . SER A 1 243 ? 13.47   -29.72  -12.848 1   17.67  ? 239 SER A O   1 
ATOM   1957 C  CB  . SER A 1 243 ? 14.133  -27.252 -14.325 1   19.97  ? 239 SER A CB  1 
ATOM   1958 O  OG  . SER A 1 243 ? 13.758  -26.318 -13.314 1   21.21  ? 239 SER A OG  1 
ATOM   1959 N  N   . PHE A 1 244 ? 11.414  -28.844 -12.819 1   18.26  ? 240 PHE A N   1 
ATOM   1960 C  CA  . PHE A 1 244 ? 10.985  -29.633 -11.676 1   19.53  ? 240 PHE A CA  1 
ATOM   1961 C  C   . PHE A 1 244 ? 11.22   -31.116 -11.937 1   20.82  ? 240 PHE A C   1 
ATOM   1962 O  O   . PHE A 1 244 ? 10.824  -31.641 -12.979 1   19.79  ? 240 PHE A O   1 
ATOM   1963 C  CB  . PHE A 1 244 ? 9.494   -29.463 -11.397 1   19.43  ? 240 PHE A CB  1 
ATOM   1964 C  CG  . PHE A 1 244 ? 9.138   -28.192 -10.652 1   21.97  ? 240 PHE A CG  1 
ATOM   1965 C  CD1 . PHE A 1 244 ? 10.119  -27.41  -10.043 1   24.87  ? 240 PHE A CD1 1 
ATOM   1966 C  CD2 . PHE A 1 244 ? 7.816   -27.798 -10.541 1   22.61  ? 240 PHE A CD2 1 
ATOM   1967 C  CE1 . PHE A 1 244 ? 9.782   -26.239 -9.374  1   25.22  ? 240 PHE A CE1 1 
ATOM   1968 C  CE2 . PHE A 1 244 ? 7.487   -26.632 -9.881  1   23.79  ? 240 PHE A CE2 1 
ATOM   1969 C  CZ  . PHE A 1 244 ? 8.464   -25.863 -9.295  1   24.94  ? 240 PHE A CZ  1 
ATOM   1970 N  N   . PRO A 1 245 ? 11.844  -31.848 -10.985 1   23.66  ? 241 PRO A N   1 
ATOM   1971 C  CA  . PRO A 1 245 ? 12.08   -33.281 -11.185 1   23.87  ? 241 PRO A CA  1 
ATOM   1972 C  C   . PRO A 1 245 ? 10.715  -33.931 -11.385 1   23.26  ? 241 PRO A C   1 
ATOM   1973 O  O   . PRO A 1 245 ? 9.712   -33.472 -10.818 1   19.99  ? 241 PRO A O   1 
ATOM   1974 C  CB  . PRO A 1 245 ? 12.781  -33.696 -9.874  1   24.8   ? 241 PRO A CB  1 
ATOM   1975 C  CG  . PRO A 1 245 ? 13.412  -32.396 -9.377  1   24.58  ? 241 PRO A CG  1 
ATOM   1976 C  CD  . PRO A 1 245 ? 12.336  -31.358 -9.68   1   23.02  ? 241 PRO A CD  1 
ATOM   1977 N  N   . LYS A 1 246 ? 10.68   -34.967 -12.24  1   26.33  ? 242 LYS A N   1 
ATOM   1978 C  CA  . LYS A 1 246 ? 9.42    -35.648 -12.538 1   29.69  ? 242 LYS A CA  1 
ATOM   1979 C  C   . LYS A 1 246 ? 9.386   -36.959 -11.756 1   25.98  ? 242 LYS A C   1 
ATOM   1980 O  O   . LYS A 1 246 ? 10.062  -37.89  -12.147 1   29.18  ? 242 LYS A O   1 
ATOM   1981 C  CB  . LYS A 1 246 ? 9.212   -35.786 -14.055 1   30.17  ? 242 LYS A CB  1 
ATOM   1982 C  CG  . LYS A 1 246 ? 8.862   -34.472 -14.75  1   37.08  ? 242 LYS A CG  1 
ATOM   1983 C  CD  . LYS A 1 246 ? 8.555   -34.622 -16.233 1   47.32  ? 242 LYS A CD  1 
ATOM   1984 C  CE  . LYS A 1 246 ? 7.866   -33.44  -16.834 1   49.44  ? 242 LYS A CE  1 
ATOM   1985 N  NZ  . LYS A 1 246 ? 8.854   -32.54  -17.424 1   56.76  ? 242 LYS A NZ  1 
ATOM   1986 N  N   . TRP A 1 247 ? 8.678   -36.977 -10.617 1   23.9   ? 243 TRP A N   1 
ATOM   1987 C  CA  . TRP A 1 247 ? 8.619   -38.121 -9.716  1   22.21  ? 243 TRP A CA  1 
ATOM   1988 C  C   . TRP A 1 247 ? 7.383   -38.945 -10.045 1   21.61  ? 243 TRP A C   1 
ATOM   1989 O  O   . TRP A 1 247 ? 6.303   -38.395 -10.223 1   20.9   ? 243 TRP A O   1 
ATOM   1990 C  CB  . TRP A 1 247 ? 8.595   -37.67  -8.24   1   20.07  ? 243 TRP A CB  1 
ATOM   1991 C  CG  . TRP A 1 247 ? 9.957   -37.348 -7.673  1   20.4   ? 243 TRP A CG  1 
ATOM   1992 C  CD1 . TRP A 1 247 ? 10.946  -38.24  -7.384  1   19.56  ? 243 TRP A CD1 1 
ATOM   1993 C  CD2 . TRP A 1 247 ? 10.473  -36.048 -7.301  1   20.93  ? 243 TRP A CD2 1 
ATOM   1994 N  NE1 . TRP A 1 247 ? 12.05   -37.592 -6.903  1   20.65  ? 243 TRP A NE1 1 
ATOM   1995 C  CE2 . TRP A 1 247 ? 11.786  -36.248 -6.821  1   22.1   ? 243 TRP A CE2 1 
ATOM   1996 C  CE3 . TRP A 1 247 ? 9.958   -34.745 -7.305  1   22.21  ? 243 TRP A CE3 1 
ATOM   1997 C  CZ2 . TRP A 1 247 ? 12.585  -35.188 -6.372  1   23.23  ? 243 TRP A CZ2 1 
ATOM   1998 C  CZ3 . TRP A 1 247 ? 10.738  -33.702 -6.84   1   23.17  ? 243 TRP A CZ3 1 
ATOM   1999 C  CH2 . TRP A 1 247 ? 12.045  -33.916 -6.399  1   23.02  ? 243 TRP A CH2 1 
ATOM   2000 N  N   . ALA A 1 248 ? 7.545   -40.266 -10.093 1   23.56  ? 244 ALA A N   1 
ATOM   2001 C  CA  . ALA A 1 248 ? 6.404   -41.165 -10.244 1   24.88  ? 244 ALA A CA  1 
ATOM   2002 C  C   . ALA A 1 248 ? 5.492   -41.091 -9.022  1   29.67  ? 244 ALA A C   1 
ATOM   2003 O  O   . ALA A 1 248 ? 5.932   -40.886 -7.883  1   32.62  ? 244 ALA A O   1 
ATOM   2004 C  CB  . ALA A 1 248 ? 6.87    -42.577 -10.48  1   20.63  ? 244 ALA A CB  1 
ATOM   2005 N  N   . ARG A 1 249 ? 4.193   -41.256 -9.276  1   32.57  ? 245 ARG A N   1 
ATOM   2006 C  CA  . ARG A 1 249 ? 3.229   -41.242 -8.192  1   32.99  ? 245 ARG A CA  1 
ATOM   2007 C  C   . ARG A 1 249 ? 3.295   -42.609 -7.535  1   35.51  ? 245 ARG A C   1 
ATOM   2008 O  O   . ARG A 1 249 ? 3.1     -43.622 -8.193  1   37.43  ? 245 ARG A O   1 
ATOM   2009 C  CB  . ARG A 1 249 ? 1.851   -40.97  -8.793  1   30.93  ? 245 ARG A CB  1 
ATOM   2010 C  CG  . ARG A 1 249 ? 0.709   -41.268 -7.842  1   29.79  ? 245 ARG A CG  1 
ATOM   2011 C  CD  . ARG A 1 249 ? -0.605  -40.795 -8.443  1   28.86  ? 245 ARG A CD  1 
ATOM   2012 N  NE  . ARG A 1 249 ? -1.629  -40.99  -7.403  1   32.66  ? 245 ARG A NE  1 
ATOM   2013 C  CZ  . ARG A 1 249 ? -2.068  -40.05  -6.558  1   32.69  ? 245 ARG A CZ  1 
ATOM   2014 N  NH1 . ARG A 1 249 ? -1.472  -38.86  -6.519  1   29.73  ? 245 ARG A NH1 1 
ATOM   2015 N  NH2 . ARG A 1 249 ? -3.06   -40.345 -5.722  1   34.32  ? 245 ARG A NH2 1 
ATOM   2016 N  N   . GLN A 1 250 ? 3.627   -42.644 -6.251  1   42.55  ? 246 GLN A N   1 
ATOM   2017 C  CA  . GLN A 1 250 ? 3.654   -43.932 -5.581  1   43.82  ? 246 GLN A CA  1 
ATOM   2018 C  C   . GLN A 1 250 ? 2.218   -44.333 -5.244  1   48.26  ? 246 GLN A C   1 
ATOM   2019 O  O   . GLN A 1 250 ? 1.342   -43.486 -4.992  1   46.56  ? 246 GLN A O   1 
ATOM   2020 C  CB  . GLN A 1 250 ? 4.523   -43.89  -4.329  1   37.31  ? 246 GLN A CB  1 
ATOM   2021 C  CG  . GLN A 1 250 ? 3.827   -43.193 -3.167  1   34.51  ? 246 GLN A CG  1 
ATOM   2022 C  CD  . GLN A 1 250 ? 4.786   -43.009 -2.023  1   40.53  ? 246 GLN A CD  1 
ATOM   2023 O  OE1 . GLN A 1 250 ? 4.971   -41.906 -1.511  1   55.88  ? 246 GLN A OE1 1 
ATOM   2024 N  NE2 . GLN A 1 250 ? 5.47    -44.077 -1.654  1   42.75  ? 246 GLN A NE2 1 
ATOM   2025 N  N   . ASP A 1 251 ? 2.014   -45.652 -5.262  1   45.94  ? 247 ASP A N   1 
ATOM   2026 C  CA  . ASP A 1 251 ? 0.777   -46.28  -4.841  1   46.25  ? 247 ASP A CA  1 
ATOM   2027 C  C   . ASP A 1 251 ? 0.327   -45.645 -3.523  1   37.76  ? 247 ASP A C   1 
ATOM   2028 O  O   . ASP A 1 251 ? 1.093   -45.571 -2.573  1   40.79  ? 247 ASP A O   1 
ATOM   2029 C  CB  . ASP A 1 251 ? 0.966   -47.792 -4.928  1   58.34  ? 247 ASP A CB  1 
ATOM   2030 C  CG  . ASP A 1 251 ? -0.026  -48.672 -4.18   1   72.39  ? 247 ASP A CG  1 
ATOM   2031 O  OD1 . ASP A 1 251 ? -1.259  -48.436 -4.32   1   71.27  ? 247 ASP A OD1 1 
ATOM   2032 O  OD2 . ASP A 1 251 ? 0.45    -49.624 -3.505  1   76.8   ? 247 ASP A OD2 1 
ATOM   2033 N  N   . PHE A 1 252 ? -0.918  -45.169 -3.477  1   31.27  ? 248 PHE A N   1 
ATOM   2034 C  CA  . PHE A 1 252 ? -1.451  -44.435 -2.339  1   30.12  ? 248 PHE A CA  1 
ATOM   2035 C  C   . PHE A 1 252 ? -1.534  -45.264 -1.047  1   31.8   ? 248 PHE A C   1 
ATOM   2036 O  O   . PHE A 1 252 ? -1.646  -44.722 0.064   1   32.98  ? 248 PHE A O   1 
ATOM   2037 C  CB  . PHE A 1 252 ? -2.828  -43.921 -2.766  1   30.52  ? 248 PHE A CB  1 
ATOM   2038 C  CG  . PHE A 1 252 ? -3.111  -42.597 -2.076  1   31.09  ? 248 PHE A CG  1 
ATOM   2039 C  CD1 . PHE A 1 252 ? -2.574  -41.42  -2.6    1   30.89  ? 248 PHE A CD1 1 
ATOM   2040 C  CD2 . PHE A 1 252 ? -3.847  -42.529 -0.906  1   27.82  ? 248 PHE A CD2 1 
ATOM   2041 C  CE1 . PHE A 1 252 ? -2.762  -40.205 -1.981  1   28.04  ? 248 PHE A CE1 1 
ATOM   2042 C  CE2 . PHE A 1 252 ? -4.037  -41.295 -0.294  1   30.57  ? 248 PHE A CE2 1 
ATOM   2043 C  CZ  . PHE A 1 252 ? -3.496  -40.141 -0.831  1   30.28  ? 248 PHE A CZ  1 
ATOM   2044 N  N   . SER A 1 253 ? -1.546  -46.594 -1.192  1   30.25  ? 249 SER A N   1 
ATOM   2045 C  CA  . SER A 1 253 ? -1.571  -47.478 -0.044  1   28.86  ? 249 SER A CA  1 
ATOM   2046 C  C   . SER A 1 253 ? -0.233  -47.458 0.692   1   31.25  ? 249 SER A C   1 
ATOM   2047 O  O   . SER A 1 253 ? -0.1    -48.055 1.762   1   32.59  ? 249 SER A O   1 
ATOM   2048 C  CB  . SER A 1 253 ? -1.9    -48.865 -0.492  1   28.56  ? 249 SER A CB  1 
ATOM   2049 O  OG  . SER A 1 253 ? -0.85   -49.429 -1.262  1   28.36  ? 249 SER A OG  1 
ATOM   2050 N  N   . LYS A 1 254 ? 0.777   -46.832 0.073   1   32.88  ? 250 LYS A N   1 
ATOM   2051 C  CA  . LYS A 1 254 ? 2.108   -46.753 0.651   1   31.05  ? 250 LYS A CA  1 
ATOM   2052 C  C   . LYS A 1 254 ? 2.281   -45.411 1.353   1   30.72  ? 250 LYS A C   1 
ATOM   2053 O  O   . LYS A 1 254 ? 3.234   -45.233 2.099   1   35.04  ? 250 LYS A O   1 
ATOM   2054 C  CB  . LYS A 1 254 ? 3.167   -46.951 -0.433  1   27.55  ? 250 LYS A CB  1 
ATOM   2055 C  CG  . LYS A 1 254 ? 3.179   -48.359 -0.979  1   28.53  ? 250 LYS A CG  1 
ATOM   2056 C  CD  . LYS A 1 254 ? 3.654   -49.396 0.031   1   31.6   ? 250 LYS A CD  1 
ATOM   2057 C  CE  . LYS A 1 254 ? 3.689   -50.805 -0.504  1   34.43  ? 250 LYS A CE  1 
ATOM   2058 N  NZ  . LYS A 1 254 ? 2.366   -51.437 -0.498  1   37.99  ? 250 LYS A NZ  1 
ATOM   2059 N  N   . VAL A 1 255 ? 1.354   -44.482 1.121   1   27.26  ? 251 VAL A N   1 
ATOM   2060 C  CA  . VAL A 1 255 ? 1.473   -43.164 1.701   1   26.85  ? 251 VAL A CA  1 
ATOM   2061 C  C   . VAL A 1 255 ? 1.084   -43.228 3.167   1   32.07  ? 251 VAL A C   1 
ATOM   2062 O  O   . VAL A 1 255 ? 1.772   -42.622 3.984   1   34.23  ? 251 VAL A O   1 
ATOM   2063 C  CB  . VAL A 1 255 ? 0.619   -42.119 0.983   1   24.16  ? 251 VAL A CB  1 
ATOM   2064 C  CG1 . VAL A 1 255 ? 0.635   -40.798 1.751   1   22.14  ? 251 VAL A CG1 1 
ATOM   2065 C  CG2 . VAL A 1 255 ? 1.112   -41.963 -0.447  1   22.86  ? 251 VAL A CG2 1 
ATOM   2066 N  N   . VAL A 1 256 ? -0.039  -43.903 3.468   1   32.44  ? 252 VAL A N   1 
ATOM   2067 C  CA  . VAL A 1 256 ? -0.43   -44.143 4.849   1   27.71  ? 252 VAL A CA  1 
ATOM   2068 C  C   . VAL A 1 256 ? -0.759  -45.62  5.008   1   25.25  ? 252 VAL A C   1 
ATOM   2069 O  O   . VAL A 1 256 ? -1.921  -45.984 5.068   1   22.75  ? 252 VAL A O   1 
ATOM   2070 C  CB  . VAL A 1 256 ? -1.594  -43.233 5.287   1   28.21  ? 252 VAL A CB  1 
ATOM   2071 C  CG1 . VAL A 1 256 ? -1.906  -43.385 6.776   1   26.23  ? 252 VAL A CG1 1 
ATOM   2072 C  CG2 . VAL A 1 256 ? -1.285  -41.775 4.959   1   25.08  ? 252 VAL A CG2 1 
ATOM   2073 N  N   . PRO A 1 257 ? 0.264   -46.508 5.065   1   25.38  ? 253 PRO A N   1 
ATOM   2074 C  CA  . PRO A 1 257 ? 0.036   -47.957 5.066   1   23.22  ? 253 PRO A CA  1 
ATOM   2075 C  C   . PRO A 1 257 ? -1.087  -48.499 5.951   1   25.44  ? 253 PRO A C   1 
ATOM   2076 O  O   . PRO A 1 257 ? -1.857  -49.336 5.499   1   28.98  ? 253 PRO A O   1 
ATOM   2077 C  CB  . PRO A 1 257 ? 1.4     -48.516 5.469   1   21.36  ? 253 PRO A CB  1 
ATOM   2078 C  CG  . PRO A 1 257 ? 2.388   -47.499 4.964   1   20.51  ? 253 PRO A CG  1 
ATOM   2079 C  CD  . PRO A 1 257 ? 1.7     -46.159 5.114   1   22.1   ? 253 PRO A CD  1 
ATOM   2080 N  N   . PRO A 1 258 ? -1.281  -48.063 7.215   1   24.52  ? 254 PRO A N   1 
ATOM   2081 C  CA  . PRO A 1 258 ? -2.329  -48.663 8.037   1   26.88  ? 254 PRO A CA  1 
ATOM   2082 C  C   . PRO A 1 258 ? -3.756  -48.326 7.605   1   28.66  ? 254 PRO A C   1 
ATOM   2083 O  O   . PRO A 1 258 ? -4.699  -48.799 8.22    1   32.41  ? 254 PRO A O   1 
ATOM   2084 C  CB  . PRO A 1 258 ? -2.063  -48.176 9.472   1   25.23  ? 254 PRO A CB  1 
ATOM   2085 C  CG  . PRO A 1 258 ? -0.893  -47.232 9.367   1   24.09  ? 254 PRO A CG  1 
ATOM   2086 C  CD  . PRO A 1 258 ? -0.575  -46.98  7.902   1   22.94  ? 254 PRO A CD  1 
ATOM   2087 N  N   . LEU A 1 259 ? -3.905  -47.489 6.576   1   28.47  ? 255 LEU A N   1 
ATOM   2088 C  CA  . LEU A 1 259 ? -5.199  -46.935 6.213   1   26.01  ? 255 LEU A CA  1 
ATOM   2089 C  C   . LEU A 1 259 ? -5.956  -47.921 5.327   1   26.87  ? 255 LEU A C   1 
ATOM   2090 O  O   . LEU A 1 259 ? -5.367  -48.484 4.402   1   25.58  ? 255 LEU A O   1 
ATOM   2091 C  CB  . LEU A 1 259 ? -4.925  -45.629 5.48    1   24.36  ? 255 LEU A CB  1 
ATOM   2092 C  CG  . LEU A 1 259 ? -6.051  -44.599 5.491   1   26.23  ? 255 LEU A CG  1 
ATOM   2093 C  CD1 . LEU A 1 259 ? -6.615  -44.375 6.906   1   27.44  ? 255 LEU A CD1 1 
ATOM   2094 C  CD2 . LEU A 1 259 ? -5.557  -43.284 4.907   1   24.07  ? 255 LEU A CD2 1 
ATOM   2095 N  N   A ASP A 1 260 ? -7.269  -48.035 5.607   0.5 27.14  ? 256 ASP A N   1 
ATOM   2096 N  N   B ASP A 1 260 ? -7.24   -48.173 5.633   0.5 27.87  ? 256 ASP A N   1 
ATOM   2097 C  CA  A ASP A 1 260 ? -8.203  -48.947 4.951   0.5 27.3   ? 256 ASP A CA  1 
ATOM   2098 C  CA  B ASP A 1 260 ? -8.025  -49.141 4.869   0.5 28.3   ? 256 ASP A CA  1 
ATOM   2099 C  C   A ASP A 1 260 ? -8.556  -48.414 3.563   0.5 27.56  ? 256 ASP A C   1 
ATOM   2100 C  C   B ASP A 1 260 ? -8.558  -48.46  3.606   0.5 28.21  ? 256 ASP A C   1 
ATOM   2101 O  O   A ASP A 1 260 ? -8.192  -47.29  3.22    0.5 28.49  ? 256 ASP A O   1 
ATOM   2102 O  O   B ASP A 1 260 ? -8.33   -47.269 3.398   0.5 29.2   ? 256 ASP A O   1 
ATOM   2103 C  CB  A ASP A 1 260 ? -9.452  -49.187 5.797   0.5 25.94  ? 256 ASP A CB  1 
ATOM   2104 C  CB  B ASP A 1 260 ? -9.074  -49.856 5.715   0.5 28.13  ? 256 ASP A CB  1 
ATOM   2105 C  CG  A ASP A 1 260 ? -10.213 -47.956 6.28    0.5 24.13  ? 256 ASP A CG  1 
ATOM   2106 C  CG  B ASP A 1 260 ? -8.596  -51.02  6.582   0.5 28     ? 256 ASP A CG  1 
ATOM   2107 O  OD1 A ASP A 1 260 ? -9.677  -47.232 7.15    0.5 22.74  ? 256 ASP A OD1 1 
ATOM   2108 O  OD1 B ASP A 1 260 ? -7.445  -51.455 6.409   0.5 24.31  ? 256 ASP A OD1 1 
ATOM   2109 O  OD2 A ASP A 1 260 ? -11.335 -47.735 5.786   0.5 22.33  ? 256 ASP A OD2 1 
ATOM   2110 O  OD2 B ASP A 1 260 ? -9.386  -51.49  7.435   0.5 31.38  ? 256 ASP A OD2 1 
ATOM   2111 N  N   . GLU A 1 261 ? -9.273  -49.219 2.772   1   26.88  ? 257 GLU A N   1 
ATOM   2112 C  CA  . GLU A 1 261 ? -9.661  -48.79  1.437   1   28.04  ? 257 GLU A CA  1 
ATOM   2113 C  C   . GLU A 1 261 ? -10.521 -47.514 1.462   1   29.23  ? 257 GLU A C   1 
ATOM   2114 O  O   . GLU A 1 261 ? -10.268 -46.601 0.667   1   27.46  ? 257 GLU A O   1 
ATOM   2115 C  CB  . GLU A 1 261 ? -10.316 -49.984 0.76    1   30.9   ? 257 GLU A CB  1 
ATOM   2116 C  CG  . GLU A 1 261 ? -10.732 -49.763 -0.693  1   37.71  ? 257 GLU A CG  1 
ATOM   2117 C  CD  . GLU A 1 261 ? -11.538 -50.981 -1.147  1   45.19  ? 257 GLU A CD  1 
ATOM   2118 O  OE1 . GLU A 1 261 ? -12.761 -50.865 -1.422  1   49.28  ? 257 GLU A OE1 1 
ATOM   2119 O  OE2 . GLU A 1 261 ? -10.935 -52.078 -1.178  1   46.87  ? 257 GLU A OE2 1 
ATOM   2120 N  N   . ASP A 1 262 ? -11.5   -47.426 2.393   1   27.27  ? 258 ASP A N   1 
ATOM   2121 C  CA  . ASP A 1 262 ? -12.354 -46.247 2.517   1   26.47  ? 258 ASP A CA  1 
ATOM   2122 C  C   . ASP A 1 262 ? -11.509 -45.043 2.93    1   27.49  ? 258 ASP A C   1 
ATOM   2123 O  O   . ASP A 1 262 ? -11.616 -43.945 2.366   1   25.99  ? 258 ASP A O   1 
ATOM   2124 C  CB  . ASP A 1 262 ? -13.535 -46.488 3.447   1   27.37  ? 258 ASP A CB  1 
ATOM   2125 C  CG  . ASP A 1 262 ? -14.678 -47.347 2.903   1   31.04  ? 258 ASP A CG  1 
ATOM   2126 O  OD1 . ASP A 1 262 ? -14.823 -47.47  1.661   1   28.89  ? 258 ASP A OD1 1 
ATOM   2127 O  OD2 . ASP A 1 262 ? -15.421 -47.911 3.732   1   33.65  ? 258 ASP A OD2 1 
ATOM   2128 N  N   . GLY A 1 263 ? -10.63  -45.261 3.913   1   27.75  ? 259 GLY A N   1 
ATOM   2129 C  CA  . GLY A 1 263 ? -9.732  -44.197 4.334   1   26.87  ? 259 GLY A CA  1 
ATOM   2130 C  C   . GLY A 1 263 ? -8.931  -43.647 3.156   1   26.21  ? 259 GLY A C   1 
ATOM   2131 O  O   . GLY A 1 263 ? -8.923  -42.438 2.92    1   27.15  ? 259 GLY A O   1 
ATOM   2132 N  N   . ARG A 1 264 ? -8.27   -44.551 2.413   1   24.26  ? 260 ARG A N   1 
ATOM   2133 C  CA  . ARG A 1 264 ? -7.387  -44.151 1.331   1   23.62  ? 260 ARG A CA  1 
ATOM   2134 C  C   . ARG A 1 264 ? -8.171  -43.384 0.275   1   22.95  ? 260 ARG A C   1 
ATOM   2135 O  O   . ARG A 1 264 ? -7.668  -42.413 -0.28   1   22.22  ? 260 ARG A O   1 
ATOM   2136 C  CB  . ARG A 1 264 ? -6.763  -45.335 0.596   1   25.97  ? 260 ARG A CB  1 
ATOM   2137 C  CG  . ARG A 1 264 ? -5.656  -46.065 1.333   1   27.68  ? 260 ARG A CG  1 
ATOM   2138 C  CD  . ARG A 1 264 ? -4.811  -46.856 0.348   1   25.83  ? 260 ARG A CD  1 
ATOM   2139 N  NE  . ARG A 1 264 ? -5.556  -47.968 -0.24   1   25.13  ? 260 ARG A NE  1 
ATOM   2140 C  CZ  . ARG A 1 264 ? -5.925  -49.066 0.389   1   24.83  ? 260 ARG A CZ  1 
ATOM   2141 N  NH1 . ARG A 1 264 ? -5.546  -49.309 1.634   1   26.2   ? 260 ARG A NH1 1 
ATOM   2142 N  NH2 . ARG A 1 264 ? -6.695  -49.925 -0.245  1   26.41  ? 260 ARG A NH2 1 
ATOM   2143 N  N   . SER A 1 265 ? -9.402  -43.839 0.002   1   21.51  ? 261 SER A N   1 
ATOM   2144 C  CA  . SER A 1 265 ? -10.244 -43.186 -0.986  1   20.28  ? 261 SER A CA  1 
ATOM   2145 C  C   . SER A 1 265 ? -10.476 -41.733 -0.583  1   21.75  ? 261 SER A C   1 
ATOM   2146 O  O   . SER A 1 265 ? -10.247 -40.813 -1.372  1   23.03  ? 261 SER A O   1 
ATOM   2147 C  CB  . SER A 1 265 ? -11.516 -43.958 -1.161  1   20.29  ? 261 SER A CB  1 
ATOM   2148 O  OG  . SER A 1 265 ? -12.526 -43.191 -1.8    1   23.49  ? 261 SER A OG  1 
ATOM   2149 N  N   . LEU A 1 266 ? -10.914 -41.535 0.667   1   21.98  ? 262 LEU A N   1 
ATOM   2150 C  CA  . LEU A 1 266 ? -11.243 -40.205 1.131   1   23.89  ? 262 LEU A CA  1 
ATOM   2151 C  C   . LEU A 1 266 ? -9.995  -39.33  1.071   1   28.11  ? 262 LEU A C   1 
ATOM   2152 O  O   . LEU A 1 266 ? -10.028 -38.265 0.458   1   30.98  ? 262 LEU A O   1 
ATOM   2153 C  CB  . LEU A 1 266 ? -11.888 -40.263 2.515   1   25.41  ? 262 LEU A CB  1 
ATOM   2154 C  CG  . LEU A 1 266 ? -12.094 -38.917 3.223   1   25.05  ? 262 LEU A CG  1 
ATOM   2155 C  CD1 . LEU A 1 266 ? -12.83  -37.891 2.38    1   22.51  ? 262 LEU A CD1 1 
ATOM   2156 C  CD2 . LEU A 1 266 ? -12.832 -39.149 4.52    1   23.33  ? 262 LEU A CD2 1 
ATOM   2157 N  N   . LEU A 1 267 ? -8.883  -39.84  1.62    1   29.94  ? 263 LEU A N   1 
ATOM   2158 C  CA  . LEU A 1 267 ? -7.625  -39.114 1.698   1   27.3   ? 263 LEU A CA  1 
ATOM   2159 C  C   . LEU A 1 267 ? -7.145  -38.675 0.316   1   27.13  ? 263 LEU A C   1 
ATOM   2160 O  O   . LEU A 1 267 ? -6.727  -37.523 0.142   1   29.92  ? 263 LEU A O   1 
ATOM   2161 C  CB  . LEU A 1 267 ? -6.553  -39.94  2.399   1   26.15  ? 263 LEU A CB  1 
ATOM   2162 C  CG  . LEU A 1 267 ? -5.231  -39.195 2.594   1   27.65  ? 263 LEU A CG  1 
ATOM   2163 C  CD1 . LEU A 1 267 ? -5.432  -37.891 3.397   1   24.95  ? 263 LEU A CD1 1 
ATOM   2164 C  CD2 . LEU A 1 267 ? -4.166  -40.073 3.222   1   27.24  ? 263 LEU A CD2 1 
ATOM   2165 N  N   . SER A 1 268 ? -7.167  -39.608 -0.644  1   25.3   ? 264 SER A N   1 
ATOM   2166 C  CA  . SER A 1 268 ? -6.783  -39.303 -2.015  1   27.26  ? 264 SER A CA  1 
ATOM   2167 C  C   . SER A 1 268 ? -7.616  -38.159 -2.603  1   27.3   ? 264 SER A C   1 
ATOM   2168 O  O   . SER A 1 268 ? -7.097  -37.358 -3.373  1   31.29  ? 264 SER A O   1 
ATOM   2169 C  CB  . SER A 1 268 ? -6.816  -40.519 -2.894  1   27.09  ? 264 SER A CB  1 
ATOM   2170 O  OG  . SER A 1 268 ? -8.139  -41.017 -2.955  1   31.93  ? 264 SER A OG  1 
ATOM   2171 N  N   . GLN A 1 269 ? -8.89   -38.06  -2.221  1   25.28  ? 265 GLN A N   1 
ATOM   2172 C  CA  . GLN A 1 269 ? -9.75   -37.021 -2.762  1   26.79  ? 265 GLN A CA  1 
ATOM   2173 C  C   . GLN A 1 269 ? -9.505  -35.698 -2.057  1   27.96  ? 265 GLN A C   1 
ATOM   2174 O  O   . GLN A 1 269 ? -9.773  -34.637 -2.631  1   33.02  ? 265 GLN A O   1 
ATOM   2175 C  CB  . GLN A 1 269 ? -11.223 -37.42  -2.731  1   25.7   ? 265 GLN A CB  1 
ATOM   2176 C  CG  . GLN A 1 269 ? -11.533 -38.567 -3.692  1   27.08  ? 265 GLN A CG  1 
ATOM   2177 C  CD  . GLN A 1 269 ? -12.843 -39.249 -3.403  1   28.76  ? 265 GLN A CD  1 
ATOM   2178 O  OE1 . GLN A 1 269 ? -12.884 -40.305 -2.766  1   34.84  ? 265 GLN A OE1 1 
ATOM   2179 N  NE2 . GLN A 1 269 ? -13.938 -38.608 -3.778  1   32.31  ? 265 GLN A NE2 1 
ATOM   2180 N  N   . MET A 1 270 ? -8.996  -35.77  -0.821  1   26.56  ? 266 MET A N   1 
ATOM   2181 C  CA  . MET A 1 270 ? -8.644  -34.551 -0.105  1   28.08  ? 266 MET A CA  1 
ATOM   2182 C  C   . MET A 1 270 ? -7.331  -33.974 -0.621  1   31.92  ? 266 MET A C   1 
ATOM   2183 O  O   . MET A 1 270 ? -7.172  -32.754 -0.611  1   34.5   ? 266 MET A O   1 
ATOM   2184 C  CB  . MET A 1 270 ? -8.587  -34.762 1.403   1   24.12  ? 266 MET A CB  1 
ATOM   2185 C  CG  . MET A 1 270 ? -9.968  -35.052 1.926   1   23.78  ? 266 MET A CG  1 
ATOM   2186 S  SD  . MET A 1 270 ? -10.04  -35.495 3.67    1   29.25  ? 266 MET A SD  1 
ATOM   2187 C  CE  . MET A 1 270 ? -9.972  -33.83  4.351   1   25.04  ? 266 MET A CE  1 
ATOM   2188 N  N   . LEU A 1 271 ? -6.43   -34.855 -1.095  1   31     ? 267 LEU A N   1 
ATOM   2189 C  CA  . LEU A 1 271 ? -5.099  -34.469 -1.54   1   30.68  ? 267 LEU A CA  1 
ATOM   2190 C  C   . LEU A 1 271 ? -4.988  -34.49  -3.071  1   33.35  ? 267 LEU A C   1 
ATOM   2191 O  O   . LEU A 1 271 ? -3.9    -34.618 -3.624  1   32.07  ? 267 LEU A O   1 
ATOM   2192 C  CB  . LEU A 1 271 ? -4.06   -35.384 -0.887  1   27.33  ? 267 LEU A CB  1 
ATOM   2193 C  CG  . LEU A 1 271 ? -4.011  -35.395 0.647   1   25.37  ? 267 LEU A CG  1 
ATOM   2194 C  CD1 . LEU A 1 271 ? -2.925  -36.31  1.178   1   23.71  ? 267 LEU A CD1 1 
ATOM   2195 C  CD2 . LEU A 1 271 ? -3.796  -34.011 1.203   1   25.23  ? 267 LEU A CD2 1 
ATOM   2196 N  N   . HIS A 1 272 ? -6.098  -34.326 -3.788  1   32.95  ? 268 HIS A N   1 
ATOM   2197 C  CA  . HIS A 1 272 ? -5.998  -34.239 -5.239  1   34.36  ? 268 HIS A CA  1 
ATOM   2198 C  C   . HIS A 1 272 ? -5.272  -32.944 -5.605  1   31.82  ? 268 HIS A C   1 
ATOM   2199 O  O   . HIS A 1 272 ? -5.506  -31.905 -4.973  1   31.04  ? 268 HIS A O   1 
ATOM   2200 C  CB  . HIS A 1 272 ? -7.401  -34.236 -5.849  1   36.67  ? 268 HIS A CB  1 
ATOM   2201 C  CG  . HIS A 1 272 ? -7.503  -34.683 -7.26   1   49.96  ? 268 HIS A CG  1 
ATOM   2202 N  ND1 . HIS A 1 272 ? -6.943  -34.007 -8.331  1   58.35  ? 268 HIS A ND1 1 
ATOM   2203 C  CD2 . HIS A 1 272 ? -8.122  -35.755 -7.772  1   55.21  ? 268 HIS A CD2 1 
ATOM   2204 C  CE1 . HIS A 1 272 ? -7.221  -34.651 -9.454  1   55.62  ? 268 HIS A CE1 1 
ATOM   2205 N  NE2 . HIS A 1 272 ? -7.961  -35.699 -9.141  1   58.88  ? 268 HIS A NE2 1 
ATOM   2206 N  N   . TYR A 1 273 ? -4.419  -33.01  -6.639  1   28.35  ? 269 TYR A N   1 
ATOM   2207 C  CA  . TYR A 1 273 ? -3.639  -31.855 -7.054  1   28.47  ? 269 TYR A CA  1 
ATOM   2208 C  C   . TYR A 1 273 ? -4.564  -30.726 -7.513  1   30.46  ? 269 TYR A C   1 
ATOM   2209 O  O   . TYR A 1 273 ? -4.475  -29.595 -7.029  1   30.44  ? 269 TYR A O   1 
ATOM   2210 C  CB  . TYR A 1 273 ? -2.59   -32.178 -8.118  1   25.79  ? 269 TYR A CB  1 
ATOM   2211 C  CG  . TYR A 1 273 ? -1.257  -32.646 -7.565  1   24.96  ? 269 TYR A CG  1 
ATOM   2212 C  CD1 . TYR A 1 273 ? -0.441  -31.787 -6.848  1   24.35  ? 269 TYR A CD1 1 
ATOM   2213 C  CD2 . TYR A 1 273 ? -0.809  -33.936 -7.79   1   24.95  ? 269 TYR A CD2 1 
ATOM   2214 C  CE1 . TYR A 1 273 ? 0.773   -32.217 -6.342  1   25.9   ? 269 TYR A CE1 1 
ATOM   2215 C  CE2 . TYR A 1 273 ? 0.407   -34.367 -7.298  1   27.82  ? 269 TYR A CE2 1 
ATOM   2216 C  CZ  . TYR A 1 273 ? 1.212   -33.512 -6.564  1   27.8   ? 269 TYR A CZ  1 
ATOM   2217 O  OH  . TYR A 1 273 ? 2.412   -33.975 -6.045  1   25.68  ? 269 TYR A OH  1 
ATOM   2218 N  N   . ASP A 1 274 ? -5.432  -31.051 -8.474  1   29.08  ? 270 ASP A N   1 
ATOM   2219 C  CA  . ASP A 1 274 ? -6.273  -30.071 -9.13   1   28.28  ? 270 ASP A CA  1 
ATOM   2220 C  C   . ASP A 1 274 ? -7.322  -29.587 -8.133  1   28.39  ? 270 ASP A C   1 
ATOM   2221 O  O   . ASP A 1 274 ? -8.202  -30.347 -7.759  1   32.13  ? 270 ASP A O   1 
ATOM   2222 C  CB  . ASP A 1 274 ? -6.927  -30.69  -10.355 1   25.39  ? 270 ASP A CB  1 
ATOM   2223 C  CG  . ASP A 1 274 ? -7.796  -29.734 -11.153 1   26.8   ? 270 ASP A CG  1 
ATOM   2224 O  OD1 . ASP A 1 274 ? -8.053  -28.609 -10.659 1   27.01  ? 270 ASP A OD1 1 
ATOM   2225 O  OD2 . ASP A 1 274 ? -8.172  -30.102 -12.282 1   28.88  ? 270 ASP A OD2 1 
ATOM   2226 N  N   . PRO A 1 275 ? -7.306  -28.317 -7.68   1   28.9   ? 271 PRO A N   1 
ATOM   2227 C  CA  . PRO A 1 275 ? -8.249  -27.865 -6.651  1   28.25  ? 271 PRO A CA  1 
ATOM   2228 C  C   . PRO A 1 275 ? -9.701  -28.008 -7.088  1   29.19  ? 271 PRO A C   1 
ATOM   2229 O  O   . PRO A 1 275 ? -10.583 -28.045 -6.237  1   34.83  ? 271 PRO A O   1 
ATOM   2230 C  CB  . PRO A 1 275 ? -7.91   -26.385 -6.398  1   26.94  ? 271 PRO A CB  1 
ATOM   2231 C  CG  . PRO A 1 275 ? -6.593  -26.151 -7.073  1   25.53  ? 271 PRO A CG  1 
ATOM   2232 C  CD  . PRO A 1 275 ? -6.384  -27.256 -8.112  1   27.53  ? 271 PRO A CD  1 
ATOM   2233 N  N   . ASN A 1 276 ? -9.932  -28.053 -8.406  1   26.94  ? 272 ASN A N   1 
ATOM   2234 C  CA  . ASN A 1 276 ? -11.26  -28.281 -8.971  1   30.97  ? 272 ASN A CA  1 
ATOM   2235 C  C   . ASN A 1 276 ? -11.795 -29.692 -8.689  1   29.15  ? 272 ASN A C   1 
ATOM   2236 O  O   . ASN A 1 276 ? -12.998 -29.851 -8.527  1   33.75  ? 272 ASN A O   1 
ATOM   2237 C  CB  . ASN A 1 276 ? -11.329 -28.012 -10.477 1   31.56  ? 272 ASN A CB  1 
ATOM   2238 C  CG  . ASN A 1 276 ? -11.02  -26.574 -10.819 1   33.44  ? 272 ASN A CG  1 
ATOM   2239 O  OD1 . ASN A 1 276 ? -11.478 -25.648 -10.142 1   36.39  ? 272 ASN A OD1 1 
ATOM   2240 N  ND2 . ASN A 1 276 ? -10.207 -26.36  -11.834 1   37.49  ? 272 ASN A ND2 1 
ATOM   2241 N  N   . LYS A 1 277 ? -10.942 -30.724 -8.692  1   30.65  ? 273 LYS A N   1 
ATOM   2242 C  CA  . LYS A 1 277 ? -11.377 -32.087 -8.407  1   31.22  ? 273 LYS A CA  1 
ATOM   2243 C  C   . LYS A 1 277 ? -11.31  -32.408 -6.914  1   28.99  ? 273 LYS A C   1 
ATOM   2244 O  O   . LYS A 1 277 ? -11.919 -33.376 -6.474  1   27.23  ? 273 LYS A O   1 
ATOM   2245 C  CB  . LYS A 1 277 ? -10.533 -33.13  -9.137  1   31.16  ? 273 LYS A CB  1 
ATOM   2246 C  CG  . LYS A 1 277 ? -10.327 -32.902 -10.621 1   40.66  ? 273 LYS A CG  1 
ATOM   2247 C  CD  . LYS A 1 277 ? -11.582 -32.985 -11.496 1   49.93  ? 273 LYS A CD  1 
ATOM   2248 C  CE  . LYS A 1 277 ? -11.21  -33.456 -12.89  1   55.51  ? 273 LYS A CE  1 
ATOM   2249 N  NZ  . LYS A 1 277 ? -12.273 -34.167 -13.612 1   60.62  ? 273 LYS A NZ  1 
ATOM   2250 N  N   . ARG A 1 278 ? -10.551 -31.619 -6.139  1   28.32  ? 274 ARG A N   1 
ATOM   2251 C  CA  . ARG A 1 278 ? -10.413 -31.918 -4.724  1   26.02  ? 274 ARG A CA  1 
ATOM   2252 C  C   . ARG A 1 278 ? -11.806 -31.934 -4.111  1   24.61  ? 274 ARG A C   1 
ATOM   2253 O  O   . ARG A 1 278 ? -12.635 -31.1   -4.459  1   22.87  ? 274 ARG A O   1 
ATOM   2254 C  CB  . ARG A 1 278 ? -9.531  -30.866 -4.062  1   25.92  ? 274 ARG A CB  1 
ATOM   2255 C  CG  . ARG A 1 278 ? -8.696  -31.441 -2.926  1   26.89  ? 274 ARG A CG  1 
ATOM   2256 C  CD  . ARG A 1 278 ? -7.743  -30.347 -2.386  1   24.88  ? 274 ARG A CD  1 
ATOM   2257 N  NE  . ARG A 1 278 ? -6.675  -30.021 -3.34   1   26.61  ? 274 ARG A NE  1 
ATOM   2258 C  CZ  . ARG A 1 278 ? -6.05   -28.839 -3.396  1   28.83  ? 274 ARG A CZ  1 
ATOM   2259 N  NH1 . ARG A 1 278 ? -6.29   -27.88  -2.506  1   26.91  ? 274 ARG A NH1 1 
ATOM   2260 N  NH2 . ARG A 1 278 ? -5.169  -28.624 -4.353  1   27.96  ? 274 ARG A NH2 1 
ATOM   2261 N  N   . ILE A 1 279 ? -12.073 -32.914 -3.243  1   22.41  ? 275 ILE A N   1 
ATOM   2262 C  CA  . ILE A 1 279 ? -13.387 -33.009 -2.642  1   20.84  ? 275 ILE A CA  1 
ATOM   2263 C  C   . ILE A 1 279 ? -13.662 -31.777 -1.755  1   23.51  ? 275 ILE A C   1 
ATOM   2264 O  O   . ILE A 1 279 ? -12.75  -31.208 -1.129  1   25.1   ? 275 ILE A O   1 
ATOM   2265 C  CB  . ILE A 1 279 ? -13.504 -34.351 -1.904  1   21.05  ? 275 ILE A CB  1 
ATOM   2266 C  CG1 . ILE A 1 279 ? -14.969 -34.724 -1.627  1   21.26  ? 275 ILE A CG1 1 
ATOM   2267 C  CG2 . ILE A 1 279 ? -12.636 -34.39  -0.635  1   19.64  ? 275 ILE A CG2 1 
ATOM   2268 C  CD1 . ILE A 1 279 ? -15.13  -36.11  -1.045  1   19.35  ? 275 ILE A CD1 1 
ATOM   2269 N  N   . SER A 1 280 ? -14.94  -31.368 -1.707  1   21.97  ? 276 SER A N   1 
ATOM   2270 C  CA  . SER A 1 280 ? -15.435 -30.371 -0.766  1   23.08  ? 276 SER A CA  1 
ATOM   2271 C  C   . SER A 1 280 ? -15.73  -31.027 0.58    1   25.24  ? 276 SER A C   1 
ATOM   2272 O  O   . SER A 1 280 ? -15.965 -32.236 0.631   1   22.89  ? 276 SER A O   1 
ATOM   2273 C  CB  . SER A 1 280 ? -16.698 -29.76  -1.295  1   24.77  ? 276 SER A CB  1 
ATOM   2274 O  OG  . SER A 1 280 ? -17.738 -30.731 -1.387  1   25.29  ? 276 SER A OG  1 
ATOM   2275 N  N   . ALA A 1 281 ? -15.772 -30.213 1.645   1   28.4   ? 277 ALA A N   1 
ATOM   2276 C  CA  . ALA A 1 281 ? -16.113 -30.711 2.971   1   32.24  ? 277 ALA A CA  1 
ATOM   2277 C  C   . ALA A 1 281 ? -17.547 -31.24  2.992   1   33.97  ? 277 ALA A C   1 
ATOM   2278 O  O   . ALA A 1 281 ? -17.858 -32.23  3.655   1   40.89  ? 277 ALA A O   1 
ATOM   2279 C  CB  . ALA A 1 281 ? -15.912 -29.631 4.013   1   31.55  ? 277 ALA A CB  1 
ATOM   2280 N  N   . LYS A 1 282 ? -18.418 -30.566 2.246   1   30.82  ? 278 LYS A N   1 
ATOM   2281 C  CA  . LYS A 1 282 ? -19.815 -30.951 2.108   1   28.92  ? 278 LYS A CA  1 
ATOM   2282 C  C   . LYS A 1 282 ? -19.941 -32.348 1.474   1   27.17  ? 278 LYS A C   1 
ATOM   2283 O  O   . LYS A 1 282 ? -20.605 -33.224 2.028   1   26.95  ? 278 LYS A O   1 
ATOM   2284 C  CB  . LYS A 1 282 ? -20.471 -29.739 1.425   1   26.08  ? 278 LYS A CB  1 
ATOM   2285 C  CG  . LYS A 1 282 ? -21.894 -29.842 0.991   1   27.31  ? 278 LYS A CG  1 
ATOM   2286 C  CD  . LYS A 1 282 ? -22.365 -28.697 0.095   1   30.02  ? 278 LYS A CD  1 
ATOM   2287 C  CE  . LYS A 1 282 ? -22.706 -27.421 0.801   1   32.47  ? 278 LYS A CE  1 
ATOM   2288 N  NZ  . LYS A 1 282 ? -23.857 -26.77  0.16    1   27.41  ? 278 LYS A NZ  1 
ATOM   2289 N  N   . ALA A 1 283 ? -19.302 -32.587 0.322   1   27.18  ? 279 ALA A N   1 
ATOM   2290 C  CA  . ALA A 1 283 ? -19.333 -33.905 -0.335  1   26.43  ? 279 ALA A CA  1 
ATOM   2291 C  C   . ALA A 1 283 ? -18.695 -35.004 0.518   1   26.95  ? 279 ALA A C   1 
ATOM   2292 O  O   . ALA A 1 283 ? -19.071 -36.188 0.415   1   28.7   ? 279 ALA A O   1 
ATOM   2293 C  CB  . ALA A 1 283 ? -18.627 -33.873 -1.678  1   20.62  ? 279 ALA A CB  1 
ATOM   2294 N  N   . ALA A 1 284 ? -17.663 -34.597 1.274   1   24.14  ? 280 ALA A N   1 
ATOM   2295 C  CA  . ALA A 1 284 ? -16.846 -35.508 2.042   1   21.67  ? 280 ALA A CA  1 
ATOM   2296 C  C   . ALA A 1 284 ? -17.661 -36.104 3.185   1   22.34  ? 280 ALA A C   1 
ATOM   2297 O  O   . ALA A 1 284 ? -17.327 -37.179 3.644   1   22.86  ? 280 ALA A O   1 
ATOM   2298 C  CB  . ALA A 1 284 ? -15.63  -34.806 2.54    1   20.09  ? 280 ALA A CB  1 
ATOM   2299 N  N   . LEU A 1 285 ? -18.73  -35.423 3.621   1   22.11  ? 281 LEU A N   1 
ATOM   2300 C  CA  . LEU A 1 285 ? -19.495 -35.875 4.771   1   21.97  ? 281 LEU A CA  1 
ATOM   2301 C  C   . LEU A 1 285 ? -20.244 -37.15  4.42    1   23.7   ? 281 LEU A C   1 
ATOM   2302 O  O   . LEU A 1 285 ? -20.671 -37.885 5.314   1   26.59  ? 281 LEU A O   1 
ATOM   2303 C  CB  . LEU A 1 285 ? -20.462 -34.8   5.259   1   19.47  ? 281 LEU A CB  1 
ATOM   2304 C  CG  . LEU A 1 285 ? -19.831 -33.635 6.023   1   19.2   ? 281 LEU A CG  1 
ATOM   2305 C  CD1 . LEU A 1 285 ? -20.874 -32.61  6.387   1   18.98  ? 281 LEU A CD1 1 
ATOM   2306 C  CD2 . LEU A 1 285 ? -19.115 -34.085 7.292   1   20.11  ? 281 LEU A CD2 1 
ATOM   2307 N  N   . ALA A 1 286 ? -20.449 -37.381 3.122   1   22.5   ? 282 ALA A N   1 
ATOM   2308 C  CA  . ALA A 1 286 ? -21.225 -38.545 2.72    1   20.7   ? 282 ALA A CA  1 
ATOM   2309 C  C   . ALA A 1 286 ? -20.309 -39.707 2.317   1   22.23  ? 282 ALA A C   1 
ATOM   2310 O  O   . ALA A 1 286 ? -20.803 -40.746 1.864   1   24.15  ? 282 ALA A O   1 
ATOM   2311 C  CB  . ALA A 1 286 ? -22.173 -38.164 1.62    1   17.98  ? 282 ALA A CB  1 
ATOM   2312 N  N   . HIS A 1 287 ? -18.983 -39.547 2.499   1   20.19  ? 283 HIS A N   1 
ATOM   2313 C  CA  . HIS A 1 287 ? -18.043 -40.606 2.161   1   20.45  ? 283 HIS A CA  1 
ATOM   2314 C  C   . HIS A 1 287 ? -18.296 -41.868 2.989   1   21.33  ? 283 HIS A C   1 
ATOM   2315 O  O   . HIS A 1 287 ? -18.65  -41.796 4.171   1   22.76  ? 283 HIS A O   1 
ATOM   2316 C  CB  . HIS A 1 287 ? -16.588 -40.163 2.318   1   20.91  ? 283 HIS A CB  1 
ATOM   2317 C  CG  . HIS A 1 287 ? -15.626 -41.07  1.611   1   24.9   ? 283 HIS A CG  1 
ATOM   2318 N  ND1 . HIS A 1 287 ? -15.291 -42.337 2.067   1   21.94  ? 283 HIS A ND1 1 
ATOM   2319 C  CD2 . HIS A 1 287 ? -14.933 -40.887 0.438   1   24.88  ? 283 HIS A CD2 1 
ATOM   2320 C  CE1 . HIS A 1 287 ? -14.412 -42.885 1.223   1   22.29  ? 283 HIS A CE1 1 
ATOM   2321 N  NE2 . HIS A 1 287 ? -14.189 -42.029 0.218   1   22.77  ? 283 HIS A NE2 1 
ATOM   2322 N  N   . PRO A 1 288 ? -18.17  -43.066 2.368   1   20.64  ? 284 PRO A N   1 
ATOM   2323 C  CA  . PRO A 1 288 ? -18.315 -44.339 3.091   1   20.1   ? 284 PRO A CA  1 
ATOM   2324 C  C   . PRO A 1 288 ? -17.45  -44.481 4.352   1   21.7   ? 284 PRO A C   1 
ATOM   2325 O  O   . PRO A 1 288 ? -17.854 -45.157 5.305   1   20.48  ? 284 PRO A O   1 
ATOM   2326 C  CB  . PRO A 1 288 ? -17.964 -45.398 2.061   1   17.59  ? 284 PRO A CB  1 
ATOM   2327 C  CG  . PRO A 1 288 ? -18.115 -44.721 0.714   1   16.88  ? 284 PRO A CG  1 
ATOM   2328 C  CD  . PRO A 1 288 ? -17.927 -43.239 0.921   1   18.41  ? 284 PRO A CD  1 
ATOM   2329 N  N   . PHE A 1 289 ? -16.287 -43.799 4.376   1   22.41  ? 285 PHE A N   1 
ATOM   2330 C  CA  . PHE A 1 289 ? -15.356 -43.88  5.495   1   22.07  ? 285 PHE A CA  1 
ATOM   2331 C  C   . PHE A 1 289 ? -16.079 -43.568 6.808   1   23.45  ? 285 PHE A C   1 
ATOM   2332 O  O   . PHE A 1 289 ? -15.745 -44.144 7.849   1   26.77  ? 285 PHE A O   1 
ATOM   2333 C  CB  . PHE A 1 289 ? -14.105 -43.052 5.222   1   22.01  ? 285 PHE A CB  1 
ATOM   2334 C  CG  . PHE A 1 289 ? -13.104 -42.988 6.366   1   27.36  ? 285 PHE A CG  1 
ATOM   2335 C  CD1 . PHE A 1 289 ? -12.271 -44.071 6.646   1   26.84  ? 285 PHE A CD1 1 
ATOM   2336 C  CD2 . PHE A 1 289 ? -12.972 -41.822 7.14    1   28.31  ? 285 PHE A CD2 1 
ATOM   2337 C  CE1 . PHE A 1 289 ? -11.352 -44.005 7.684   1   29.83  ? 285 PHE A CE1 1 
ATOM   2338 C  CE2 . PHE A 1 289 ? -12.058 -41.767 8.189   1   28     ? 285 PHE A CE2 1 
ATOM   2339 C  CZ  . PHE A 1 289 ? -11.255 -42.86  8.467   1   29.68  ? 285 PHE A CZ  1 
ATOM   2340 N  N   . PHE A 1 290 ? -17.127 -42.737 6.733   1   21.06  ? 286 PHE A N   1 
ATOM   2341 C  CA  . PHE A 1 290 ? -17.861 -42.31  7.915   1   21.41  ? 286 PHE A CA  1 
ATOM   2342 C  C   . PHE A 1 290 ? -19.107 -43.146 8.21    1   25.6   ? 286 PHE A C   1 
ATOM   2343 O  O   . PHE A 1 290 ? -19.843 -42.776 9.136   1   28.03  ? 286 PHE A O   1 
ATOM   2344 C  CB  . PHE A 1 290 ? -18.304 -40.847 7.807   1   19.01  ? 286 PHE A CB  1 
ATOM   2345 C  CG  . PHE A 1 290 ? -17.118 -39.926 7.591   1   19.58  ? 286 PHE A CG  1 
ATOM   2346 C  CD1 . PHE A 1 290 ? -16.164 -39.781 8.591   1   19.42  ? 286 PHE A CD1 1 
ATOM   2347 C  CD2 . PHE A 1 290 ? -16.933 -39.256 6.386   1   18.39  ? 286 PHE A CD2 1 
ATOM   2348 C  CE1 . PHE A 1 290 ? -15.083 -38.949 8.398   1   19.14  ? 286 PHE A CE1 1 
ATOM   2349 C  CE2 . PHE A 1 290 ? -15.835 -38.43  6.205   1   19.05  ? 286 PHE A CE2 1 
ATOM   2350 C  CZ  . PHE A 1 290 ? -14.908 -38.284 7.206   1   20.15  ? 286 PHE A CZ  1 
ATOM   2351 N  N   . GLN A 1 291 ? -19.351 -44.241 7.459   1   28.42  ? 287 GLN A N   1 
ATOM   2352 C  CA  . GLN A 1 291 ? -20.587 -45.014 7.592   1   32.03  ? 287 GLN A CA  1 
ATOM   2353 C  C   . GLN A 1 291 ? -20.871 -45.383 9.048   1   36.54  ? 287 GLN A C   1 
ATOM   2354 O  O   . GLN A 1 291 ? -22.025 -45.409 9.467   1   45.68  ? 287 GLN A O   1 
ATOM   2355 C  CB  . GLN A 1 291 ? -20.681 -46.273 6.724   1   33.93  ? 287 GLN A CB  1 
ATOM   2356 C  CG  . GLN A 1 291 ? -19.659 -47.35  7.073   1   43.35  ? 287 GLN A CG  1 
ATOM   2357 C  CD  . GLN A 1 291 ? -19.648 -48.529 6.117   1   50.39  ? 287 GLN A CD  1 
ATOM   2358 O  OE1 . GLN A 1 291 ? -20.362 -49.529 6.292   1   59.1   ? 287 GLN A OE1 1 
ATOM   2359 N  NE2 . GLN A 1 291 ? -18.795 -48.437 5.108   1   42.16  ? 287 GLN A NE2 1 
ATOM   2360 N  N   . ASP A 1 292 ? -19.821 -45.672 9.821   1   38.63  ? 288 ASP A N   1 
ATOM   2361 C  CA  . ASP A 1 292 ? -19.968 -46.317 11.115  1   41.46  ? 288 ASP A CA  1 
ATOM   2362 C  C   . ASP A 1 292 ? -19.681 -45.342 12.266  1   43.25  ? 288 ASP A C   1 
ATOM   2363 O  O   . ASP A 1 292 ? -19.544 -45.786 13.405  1   43.21  ? 288 ASP A O   1 
ATOM   2364 C  CB  . ASP A 1 292 ? -19.168 -47.616 11.154  1   43.6   ? 288 ASP A CB  1 
ATOM   2365 C  CG  . ASP A 1 292 ? -17.686 -47.523 10.789  1   55.85  ? 288 ASP A CG  1 
ATOM   2366 O  OD1 . ASP A 1 292 ? -17.237 -46.498 10.179  1   57.34  ? 288 ASP A OD1 1 
ATOM   2367 O  OD2 . ASP A 1 292 ? -16.968 -48.491 11.107  1   58.14  ? 288 ASP A OD2 1 
ATOM   2368 N  N   . VAL A 1 293 ? -19.601 -44.025 11.984  1   40.03  ? 289 VAL A N   1 
ATOM   2369 C  CA  . VAL A 1 293 ? -19.477 -43.024 13.035  1   40.25  ? 289 VAL A CA  1 
ATOM   2370 C  C   . VAL A 1 293 ? -20.831 -42.9   13.721  1   45.19  ? 289 VAL A C   1 
ATOM   2371 O  O   . VAL A 1 293 ? -21.822 -42.708 13.028  1   48.23  ? 289 VAL A O   1 
ATOM   2372 C  CB  . VAL A 1 293 ? -19.074 -41.649 12.485  1   35.16  ? 289 VAL A CB  1 
ATOM   2373 C  CG1 . VAL A 1 293 ? -18.788 -40.691 13.624  1   41.7   ? 289 VAL A CG1 1 
ATOM   2374 C  CG2 . VAL A 1 293 ? -17.857 -41.738 11.6    1   33.77  ? 289 VAL A CG2 1 
ATOM   2375 N  N   . THR A 1 294 ? -20.881 -43.001 15.059  1   56.42  ? 290 THR A N   1 
ATOM   2376 C  CA  . THR A 1 294 ? -22.162 -42.859 15.757  1   67.88  ? 290 THR A CA  1 
ATOM   2377 C  C   . THR A 1 294 ? -22.044 -41.866 16.913  1   71.48  ? 290 THR A C   1 
ATOM   2378 O  O   . THR A 1 294 ? -23.065 -41.576 17.542  1   65.37  ? 290 THR A O   1 
ATOM   2379 C  CB  . THR A 1 294 ? -22.814 -44.17  16.237  1   69.35  ? 290 THR A CB  1 
ATOM   2380 O  OG1 . THR A 1 294 ? -21.984 -44.828 17.191  1   63.37  ? 290 THR A OG1 1 
ATOM   2381 C  CG2 . THR A 1 294 ? -23.181 -45.148 15.132  1   64.46  ? 290 THR A CG2 1 
ATOM   2382 N  N   . LYS A 1 295 ? -20.823 -41.366 17.151  1   74.42  ? 291 LYS A N   1 
ATOM   2383 C  CA  . LYS A 1 295 ? -20.598 -40.375 18.237  1   79.37  ? 291 LYS A CA  1 
ATOM   2384 C  C   . LYS A 1 295 ? -21.609 -39.241 18.048  1   88.94  ? 291 LYS A C   1 
ATOM   2385 O  O   . LYS A 1 295 ? -21.526 -38.517 17.034  1   87.32  ? 291 LYS A O   1 
ATOM   2386 C  CB  . LYS A 1 295 ? -19.177 -39.805 18.311  1   63.27  ? 291 LYS A CB  1 
ATOM   2387 C  CG  . LYS A 1 295 ? -18.861 -39.192 19.666  1   56.28  ? 291 LYS A CG  1 
ATOM   2388 C  CD  . LYS A 1 295 ? -17.738 -38.165 19.651  1   57.54  ? 291 LYS A CD  1 
ATOM   2389 C  CE  . LYS A 1 295 ? -16.432 -38.76  20.083  1   55.28  ? 291 LYS A CE  1 
ATOM   2390 N  NZ  . LYS A 1 295 ? -15.294 -38.093 19.446  1   53.03  ? 291 LYS A NZ  1 
ATOM   2391 N  N   . PRO A 1 296 ? -22.554 -39.049 18.985  1   92.79  ? 292 PRO A N   1 
ATOM   2392 C  CA  . PRO A 1 296 ? -23.626 -38.055 18.806  1   86.07  ? 292 PRO A CA  1 
ATOM   2393 C  C   . PRO A 1 296 ? -23.145 -36.617 18.64   1   80.92  ? 292 PRO A C   1 
ATOM   2394 O  O   . PRO A 1 296 ? -22.177 -36.221 19.281  1   92.08  ? 292 PRO A O   1 
ATOM   2395 C  CB  . PRO A 1 296 ? -24.552 -38.206 20.045  1   86.92  ? 292 PRO A CB  1 
ATOM   2396 C  CG  . PRO A 1 296 ? -23.729 -38.993 21.042  1   90.97  ? 292 PRO A CG  1 
ATOM   2397 C  CD  . PRO A 1 296 ? -22.727 -39.815 20.237  1   96.53  ? 292 PRO A CD  1 
ATOM   2398 N  N   . VAL A 1 297 ? -23.839 -35.854 17.786  1   73.42  ? 293 VAL A N   1 
ATOM   2399 C  CA  . VAL A 1 297 ? -23.435 -34.499 17.442  1   76.36  ? 293 VAL A CA  1 
ATOM   2400 C  C   . VAL A 1 297 ? -23.262 -33.657 18.714  1   75.87  ? 293 VAL A C   1 
ATOM   2401 O  O   . VAL A 1 297 ? -24.083 -33.742 19.631  1   68.7   ? 293 VAL A O   1 
ATOM   2402 C  CB  . VAL A 1 297 ? -24.389 -33.879 16.393  1   73.8   ? 293 VAL A CB  1 
ATOM   2403 C  CG1 . VAL A 1 297 ? -24.883 -32.482 16.756  1   80.29  ? 293 VAL A CG1 1 
ATOM   2404 C  CG2 . VAL A 1 297 ? -23.779 -33.889 14.998  1   61.55  ? 293 VAL A CG2 1 
ATOM   2405 N  N   . PRO A 1 298 ? -22.163 -32.858 18.842  1   78.71  ? 294 PRO A N   1 
ATOM   2406 C  CA  . PRO A 1 298 ? -22.026 -31.918 19.967  1   68.04  ? 294 PRO A CA  1 
ATOM   2407 C  C   . PRO A 1 298 ? -23.141 -30.867 19.931  1   69.74  ? 294 PRO A C   1 
ATOM   2408 O  O   . PRO A 1 298 ? -23.651 -30.523 18.86   1   67.27  ? 294 PRO A O   1 
ATOM   2409 C  CB  . PRO A 1 298 ? -20.603 -31.302 19.773  1   63.26  ? 294 PRO A CB  1 
ATOM   2410 C  CG  . PRO A 1 298 ? -19.898 -32.23  18.783  1   60.6   ? 294 PRO A CG  1 
ATOM   2411 C  CD  . PRO A 1 298 ? -21.006 -32.804 17.913  1   67.18  ? 294 PRO A CD  1 
ATOM   2412 N  N   . HIS A 1 299 ? -23.524 -30.348 21.107  1   79.79  ? 295 HIS A N   1 
ATOM   2413 C  CA  . HIS A 1 299 ? -24.506 -29.268 21.178  1   88.36  ? 295 HIS A CA  1 
ATOM   2414 C  C   . HIS A 1 299 ? -23.873 -27.918 20.804  1   85.82  ? 295 HIS A C   1 
ATOM   2415 O  O   . HIS A 1 299 ? -22.65  -27.75  20.884  1   79.61  ? 295 HIS A O   1 
ATOM   2416 C  CB  . HIS A 1 299 ? -25.302 -29.328 22.491  1   92.44  ? 295 HIS A CB  1 
ATOM   2417 C  CG  . HIS A 1 299 ? -26.297 -30.449 22.541  1   110.15 ? 295 HIS A CG  1 
ATOM   2418 N  ND1 . HIS A 1 299 ? -26.23  -31.502 23.433  1   115.66 ? 295 HIS A ND1 1 
ATOM   2419 C  CD2 . HIS A 1 299 ? -27.412 -30.656 21.816  1   118.09 ? 295 HIS A CD2 1 
ATOM   2420 C  CE1 . HIS A 1 299 ? -27.259 -32.319 23.236  1   113.6  ? 295 HIS A CE1 1 
ATOM   2421 N  NE2 . HIS A 1 299 ? -27.99  -31.825 22.256  1   122.72 ? 295 HIS A NE2 1 
ATOM   2422 N  N   . LEU A 1 300 ? -24.73  -26.959 20.411  1   76.95  ? 296 LEU A N   1 
ATOM   2423 C  CA  . LEU A 1 300 ? -24.342 -25.717 19.742  1   82.26  ? 296 LEU A CA  1 
ATOM   2424 C  C   . LEU A 1 300 ? -23.445 -24.833 20.626  1   94.6   ? 296 LEU A C   1 
ATOM   2425 O  O   . LEU A 1 300 ? -22.407 -24.324 20.149  1   90.23  ? 296 LEU A O   1 
ATOM   2426 C  CB  . LEU A 1 300 ? -25.617 -24.971 19.329  1   82.35  ? 296 LEU A CB  1 
ATOM   2427 C  CG  . LEU A 1 300 ? -25.476 -23.723 18.44   1   77.23  ? 296 LEU A CG  1 
ATOM   2428 C  CD1 . LEU A 1 300 ? -26.633 -23.522 17.471  1   73.13  ? 296 LEU A CD1 1 
ATOM   2429 C  CD2 . LEU A 1 300 ? -25.164 -22.444 19.213  1   70.21  ? 296 LEU A CD2 1 
ATOM   2430 N  N   . ARG A 1 301 ? -23.878 -24.654 21.897  1   79.66  ? 297 ARG A N   1 
ATOM   2431 C  CA  . ARG A 1 301 ? -23.413 -23.63  22.837  1   71.47  ? 297 ARG A CA  1 
ATOM   2432 C  C   . ARG A 1 301 ? -24.127 -22.287 22.62   1   64.94  ? 297 ARG A C   1 
ATOM   2433 O  O   . ARG A 1 301 ? -24.43  -21.907 21.485  1   55.02  ? 297 ARG A O   1 
ATOM   2434 C  CB  . ARG A 1 301 ? -21.902 -23.372 22.817  1   73.25  ? 297 ARG A CB  1 
ATOM   2435 C  CG  . ARG A 1 301 ? -21.049 -24.361 23.592  1   71.63  ? 297 ARG A CG  1 
ATOM   2436 C  CD  . ARG A 1 301 ? -19.937 -23.552 24.241  1   73.75  ? 297 ARG A CD  1 
ATOM   2437 N  NE  . ARG A 1 301 ? -20.281 -23.133 25.607  1   77.31  ? 297 ARG A NE  1 
ATOM   2438 C  CZ  . ARG A 1 301 ? -20.334 -24.01  26.608  1   76.21  ? 297 ARG A CZ  1 
ATOM   2439 N  NH1 . ARG A 1 301 ? -20.141 -25.291 26.354  1   70.29  ? 297 ARG A NH1 1 
ATOM   2440 N  NH2 . ARG A 1 301 ? -20.593 -23.621 27.843  1   71.35  ? 297 ARG A NH2 1 
ATOM   2441 N  N   . LEU A 1 302 ? -24.353 -21.546 23.721  1   62.88  ? 298 LEU A N   1 
ATOM   2442 C  CA  . LEU A 1 302 ? -25.019 -20.244 23.687  1   60.77  ? 298 LEU A CA  1 
ATOM   2443 C  C   . LEU A 1 302 ? -24.233 -19.203 24.508  1   53.85  ? 298 LEU A C   1 
ATOM   2444 O  O   . LEU A 1 302 ? -23.062 -19.499 24.832  1   55.73  ? 298 LEU A O   1 
ATOM   2445 C  CB  . LEU A 1 302 ? -26.485 -20.34  24.124  1   58.41  ? 298 LEU A CB  1 
ATOM   2446 C  CG  . LEU A 1 302 ? -26.746 -20.819 25.559  1   54.27  ? 298 LEU A CG  1 
ATOM   2447 C  CD1 . LEU A 1 302 ? -26.568 -19.74  26.613  1   50.82  ? 298 LEU A CD1 1 
ATOM   2448 C  CD2 . LEU A 1 302 ? -28.114 -21.445 25.679  1   50.65  ? 298 LEU A CD2 1 
ATOM   2449 N  N   . GLY B 2 1   ? -13.689 -24.702 -11.471 1   43.62  ? 171 GLY B N   1 
ATOM   2450 C  CA  . GLY B 2 1   ? -14.896 -24.079 -10.914 1   36.49  ? 171 GLY B CA  1 
ATOM   2451 C  C   . GLY B 2 1   ? -14.732 -23.765 -9.422  1   37.56  ? 171 GLY B C   1 
ATOM   2452 O  O   . GLY B 2 1   ? -15.558 -23.019 -8.878  1   44.27  ? 171 GLY B O   1 
ATOM   2453 N  N   . VAL B 2 2   ? -13.706 -24.326 -8.756  1   28.46  ? 172 VAL B N   1 
ATOM   2454 C  CA  . VAL B 2 2   ? -13.577 -24.152 -7.31   1   27.64  ? 172 VAL B CA  1 
ATOM   2455 C  C   . VAL B 2 2   ? -13.452 -22.672 -6.921  1   27.79  ? 172 VAL B C   1 
ATOM   2456 O  O   . VAL B 2 2   ? -13.897 -22.295 -5.842  1   32.04  ? 172 VAL B O   1 
ATOM   2457 C  CB  . VAL B 2 2   ? -12.525 -25.024 -6.59   1   25.38  ? 172 VAL B CB  1 
ATOM   2458 C  CG1 . VAL B 2 2   ? -11.124 -24.429 -6.704  1   25.41  ? 172 VAL B CG1 1 
ATOM   2459 C  CG2 . VAL B 2 2   ? -12.872 -25.208 -5.115  1   21.58  ? 172 VAL B CG2 1 
ATOM   2460 N  N   . ASN B 2 3   ? -12.871 -21.834 -7.795  1   28.09  ? 173 ASN B N   1 
ATOM   2461 C  CA  . ASN B 2 3   ? -12.824 -20.386 -7.616  1   27.35  ? 173 ASN B CA  1 
ATOM   2462 C  C   . ASN B 2 3   ? -14.237 -19.814 -7.566  1   26.82  ? 173 ASN B C   1 
ATOM   2463 O  O   . ASN B 2 3   ? -14.458 -18.745 -7.019  1   30     ? 173 ASN B O   1 
ATOM   2464 C  CB  . ASN B 2 3   ? -11.981 -19.704 -8.691  1   26.37  ? 173 ASN B CB  1 
ATOM   2465 C  CG  . ASN B 2 3   ? -10.527 -20.116 -8.617  1   29.44  ? 173 ASN B CG  1 
ATOM   2466 O  OD1 . ASN B 2 3   ? -10.054 -20.67  -7.608  1   28.75  ? 173 ASN B OD1 1 
ATOM   2467 N  ND2 . ASN B 2 3   ? -9.796  -19.853 -9.689  1   30.73  ? 173 ASN B ND2 1 
ATOM   2468 N  N   . GLU B 2 4   ? -15.193 -20.544 -8.139  1   29     ? 174 GLU B N   1 
ATOM   2469 C  CA  . GLU B 2 4   ? -16.594 -20.16  -8.124  1   28.95  ? 174 GLU B CA  1 
ATOM   2470 C  C   . GLU B 2 4   ? -17.376 -21.032 -7.139  1   27.69  ? 174 GLU B C   1 
ATOM   2471 O  O   . GLU B 2 4   ? -18.596 -21.054 -7.202  1   30.32  ? 174 GLU B O   1 
ATOM   2472 C  CB  . GLU B 2 4   ? -17.158 -20.404 -9.519  1   32.37  ? 174 GLU B CB  1 
ATOM   2473 C  CG  . GLU B 2 4   ? -16.249 -19.906 -10.636 1   37.6   ? 174 GLU B CG  1 
ATOM   2474 C  CD  . GLU B 2 4   ? -16.927 -20.018 -11.987 1   42.8   ? 174 GLU B CD  1 
ATOM   2475 O  OE1 . GLU B 2 4   ? -17.86  -20.841 -12.136 1   43.61  ? 174 GLU B OE1 1 
ATOM   2476 O  OE2 . GLU B 2 4   ? -16.523 -19.244 -12.879 1   45.79  ? 174 GLU B OE2 1 
ATOM   2477 N  N   . VAL B 2 5   ? -16.667 -21.711 -6.224  1   23.87  ? 175 VAL B N   1 
ATOM   2478 C  CA  . VAL B 2 5   ? -17.207 -22.536 -5.154  1   23.77  ? 175 VAL B CA  1 
ATOM   2479 C  C   . VAL B 2 5   ? -18.554 -23.128 -5.555  1   25.22  ? 175 VAL B C   1 
ATOM   2480 O  O   . VAL B 2 5   ? -19.587 -22.785 -4.989  1   26.7   ? 175 VAL B O   1 
ATOM   2481 C  CB  . VAL B 2 5   ? -17.251 -21.847 -3.773  1   21.76  ? 175 VAL B CB  1 
ATOM   2482 C  CG1 . VAL B 2 5   ? -15.842 -21.682 -3.215  1   19.65  ? 175 VAL B CG1 1 
ATOM   2483 C  CG2 . VAL B 2 5   ? -17.989 -20.516 -3.819  1   19.71  ? 175 VAL B CG2 1 
ATOM   2484 N  N   . PRO B 2 6   ? -18.583 -24.057 -6.535  1   27.33  ? 176 PRO B N   1 
ATOM   2485 C  CA  . PRO B 2 6   ? -19.836 -24.678 -6.971  1   25.23  ? 176 PRO B CA  1 
ATOM   2486 C  C   . PRO B 2 6   ? -20.624 -25.309 -5.82   1   28.07  ? 176 PRO B C   1 
ATOM   2487 O  O   . PRO B 2 6   ? -21.852 -25.284 -5.859  1   29.75  ? 176 PRO B O   1 
ATOM   2488 C  CB  . PRO B 2 6   ? -19.434 -25.746 -8.009  1   20.63  ? 176 PRO B CB  1 
ATOM   2489 C  CG  . PRO B 2 6   ? -17.934 -25.826 -7.938  1   20.52  ? 176 PRO B CG  1 
ATOM   2490 C  CD  . PRO B 2 6   ? -17.404 -24.587 -7.243  1   24.04  ? 176 PRO B CD  1 
ATOM   2491 N  N   . ASP B 2 7   ? -19.913 -25.857 -4.808  1   27.5   ? 177 ASP B N   1 
ATOM   2492 C  CA  . ASP B 2 7   ? -20.543 -26.601 -3.735  1   26.57  ? 177 ASP B CA  1 
ATOM   2493 C  C   . ASP B 2 7   ? -21.145 -25.663 -2.689  1   26.77  ? 177 ASP B C   1 
ATOM   2494 O  O   . ASP B 2 7   ? -21.954 -26.13  -1.891  1   28.93  ? 177 ASP B O   1 
ATOM   2495 C  CB  . ASP B 2 7   ? -19.661 -27.714 -3.184  1   27.93  ? 177 ASP B CB  1 
ATOM   2496 C  CG  . ASP B 2 7   ? -19.776 -29.062 -3.89   1   31.6   ? 177 ASP B CG  1 
ATOM   2497 O  OD1 . ASP B 2 7   ? -20.323 -29.089 -5.02   1   33.54  ? 177 ASP B OD1 1 
ATOM   2498 O  OD2 . ASP B 2 7   ? -19.354 -30.091 -3.299  1   30.68  ? 177 ASP B OD2 1 
ATOM   2499 N  N   . TYR B 2 8   ? -20.818 -24.354 -2.734  1   22.31  ? 178 TYR B N   1 
ATOM   2500 C  CA  . TYR B 2 8   ? -21.222 -23.426 -1.687  1   21.02  ? 178 TYR B CA  1 
ATOM   2501 C  C   . TYR B 2 8   ? -21.863 -22.147 -2.228  1   22.69  ? 178 TYR B C   1 
ATOM   2502 O  O   . TYR B 2 8   ? -22.332 -21.34  -1.438  1   20.82  ? 178 TYR B O   1 
ATOM   2503 C  CB  . TYR B 2 8   ? -20.073 -23.074 -0.724  1   19.46  ? 178 TYR B CB  1 
ATOM   2504 C  CG  . TYR B 2 8   ? -19.376 -24.265 -0.09   1   18.27  ? 178 TYR B CG  1 
ATOM   2505 C  CD1 . TYR B 2 8   ? -19.873 -24.847 1.066   1   18.23  ? 178 TYR B CD1 1 
ATOM   2506 C  CD2 . TYR B 2 8   ? -18.269 -24.857 -0.688  1   17.51  ? 178 TYR B CD2 1 
ATOM   2507 C  CE1 . TYR B 2 8   ? -19.258 -25.946 1.644   1   17.31  ? 178 TYR B CE1 1 
ATOM   2508 C  CE2 . TYR B 2 8   ? -17.673 -25.987 -0.148  1   17.27  ? 178 TYR B CE2 1 
ATOM   2509 C  CZ  . TYR B 2 8   ? -18.145 -26.515 1.043   1   18.1   ? 178 TYR B CZ  1 
ATOM   2510 O  OH  . TYR B 2 8   ? -17.54  -27.633 1.568   1   18.12  ? 178 TYR B OH  1 
ATOM   2511 N  N   . HIS B 2 9   ? -21.928 -21.929 -3.549  1   26.61  ? 179 HIS B N   1 
ATOM   2512 C  CA  . HIS B 2 9   ? -22.386 -20.619 -4.024  1   30.2   ? 179 HIS B CA  1 
ATOM   2513 C  C   . HIS B 2 9   ? -23.84  -20.337 -3.619  1   30.18  ? 179 HIS B C   1 
ATOM   2514 O  O   . HIS B 2 9   ? -24.171 -19.208 -3.252  1   29.36  ? 179 HIS B O   1 
ATOM   2515 C  CB  . HIS B 2 9   ? -22.03  -20.344 -5.496  1   36.59  ? 179 HIS B CB  1 
ATOM   2516 C  CG  . HIS B 2 9   ? -22.94  -20.976 -6.493  1   52.75  ? 179 HIS B CG  1 
ATOM   2517 N  ND1 . HIS B 2 9   ? -22.994 -22.338 -6.756  1   56.7   ? 179 HIS B ND1 1 
ATOM   2518 C  CD2 . HIS B 2 9   ? -23.882 -20.408 -7.257  1   59.75  ? 179 HIS B CD2 1 
ATOM   2519 C  CE1 . HIS B 2 9   ? -23.914 -22.582 -7.682  1   56.63  ? 179 HIS B CE1 1 
ATOM   2520 N  NE2 . HIS B 2 9   ? -24.48  -21.424 -7.981  1   70.71  ? 179 HIS B NE2 1 
ATOM   2521 N  N   . GLU B 2 10  ? -24.711 -21.359 -3.659  1   30.63  ? 180 GLU B N   1 
ATOM   2522 C  CA  . GLU B 2 10  ? -26.099 -21.132 -3.287  1   32.04  ? 180 GLU B CA  1 
ATOM   2523 C  C   . GLU B 2 10  ? -26.197 -20.804 -1.803  1   28.85  ? 180 GLU B C   1 
ATOM   2524 O  O   . GLU B 2 10  ? -26.898 -19.855 -1.457  1   27.29  ? 180 GLU B O   1 
ATOM   2525 C  CB  . GLU B 2 10  ? -27.037 -22.309 -3.503  1   32.89  ? 180 GLU B CB  1 
ATOM   2526 C  CG  . GLU B 2 10  ? -27.706 -22.321 -4.865  1   46.41  ? 180 GLU B CG  1 
ATOM   2527 C  CD  . GLU B 2 10  ? -28.543 -23.598 -4.871  1   64.42  ? 180 GLU B CD  1 
ATOM   2528 O  OE1 . GLU B 2 10  ? -29.579 -23.679 -4.146  1   56.8   ? 180 GLU B OE1 1 
ATOM   2529 O  OE2 . GLU B 2 10  ? -28.104 -24.543 -5.576  1   68.97  ? 180 GLU B OE2 1 
ATOM   2530 N  N   . ASP B 2 11  ? -25.535 -21.624 -0.964  1   24.9   ? 181 ASP B N   1 
ATOM   2531 C  CA  . ASP B 2 11  ? -25.512 -21.419 0.477   1   24.12  ? 181 ASP B CA  1 
ATOM   2532 C  C   . ASP B 2 11  ? -25.066 -19.985 0.731   1   25.08  ? 181 ASP B C   1 
ATOM   2533 O  O   . ASP B 2 11  ? -25.724 -19.237 1.439   1   26.92  ? 181 ASP B O   1 
ATOM   2534 C  CB  . ASP B 2 11  ? -24.618 -22.414 1.206   1   23.8   ? 181 ASP B CB  1 
ATOM   2535 C  CG  . ASP B 2 11  ? -25.137 -23.845 1.339   1   28.57  ? 181 ASP B CG  1 
ATOM   2536 O  OD1 . ASP B 2 11  ? -26.365 -24.067 1.145   1   30.24  ? 181 ASP B OD1 1 
ATOM   2537 O  OD2 . ASP B 2 11  ? -24.319 -24.752 1.639   1   26.99  ? 181 ASP B OD2 1 
ATOM   2538 N  N   . ILE B 2 12  ? -23.949 -19.598 0.11    1   24.32  ? 182 ILE B N   1 
ATOM   2539 C  CA  . ILE B 2 12  ? -23.39  -18.286 0.323   1   23     ? 182 ILE B CA  1 
ATOM   2540 C  C   . ILE B 2 12  ? -24.401 -17.225 -0.106  1   24.98  ? 182 ILE B C   1 
ATOM   2541 O  O   . ILE B 2 12  ? -24.61  -16.278 0.647   1   28.73  ? 182 ILE B O   1 
ATOM   2542 C  CB  . ILE B 2 12  ? -22.018 -18.168 -0.357  1   22.09  ? 182 ILE B CB  1 
ATOM   2543 C  CG1 . ILE B 2 12  ? -21.015 -19.075 0.328   1   21.18  ? 182 ILE B CG1 1 
ATOM   2544 C  CG2 . ILE B 2 12  ? -21.517 -16.72  -0.433  1   20.11  ? 182 ILE B CG2 1 
ATOM   2545 C  CD1 . ILE B 2 12  ? -19.792 -19.365 -0.52   1   23.27  ? 182 ILE B CD1 1 
ATOM   2546 N  N   . HIS B 2 13  ? -25.016 -17.362 -1.293  1   24.67  ? 183 HIS B N   1 
ATOM   2547 C  CA  . HIS B 2 13  ? -25.987 -16.373 -1.749  1   22.38  ? 183 HIS B CA  1 
ATOM   2548 C  C   . HIS B 2 13  ? -27.133 -16.208 -0.729  1   26.13  ? 183 HIS B C   1 
ATOM   2549 O  O   . HIS B 2 13  ? -27.482 -15.085 -0.342  1   26.68  ? 183 HIS B O   1 
ATOM   2550 C  CB  . HIS B 2 13  ? -26.539 -16.761 -3.119  1   21.45  ? 183 HIS B CB  1 
ATOM   2551 C  CG  . HIS B 2 13  ? -27.637 -15.865 -3.593  1   23.92  ? 183 HIS B CG  1 
ATOM   2552 N  ND1 . HIS B 2 13  ? -27.396 -14.556 -3.985  1   27.25  ? 183 HIS B ND1 1 
ATOM   2553 C  CD2 . HIS B 2 13  ? -28.95  -16.025 -3.684  1   23.02  ? 183 HIS B CD2 1 
ATOM   2554 C  CE1 . HIS B 2 13  ? -28.527 -13.953 -4.31   1   22.85  ? 183 HIS B CE1 1 
ATOM   2555 N  NE2 . HIS B 2 13  ? -29.48  -14.838 -4.165  1   24.12  ? 183 HIS B NE2 1 
ATOM   2556 N  N   . THR B 2 14  ? -27.744 -17.333 -0.308  1   22.8   ? 184 THR B N   1 
ATOM   2557 C  CA  . THR B 2 14  ? -28.806 -17.338 0.679   1   22.85  ? 184 THR B CA  1 
ATOM   2558 C  C   . THR B 2 14  ? -28.365 -16.569 1.924   1   26.96  ? 184 THR B C   1 
ATOM   2559 O  O   . THR B 2 14  ? -29.152 -15.803 2.483   1   32.21  ? 184 THR B O   1 
ATOM   2560 C  CB  . THR B 2 14  ? -29.155 -18.768 1.079   1   24.37  ? 184 THR B CB  1 
ATOM   2561 O  OG1 . THR B 2 14  ? -29.772 -19.416 -0.024  1   24.26  ? 184 THR B OG1 1 
ATOM   2562 C  CG2 . THR B 2 14  ? -30.048 -18.829 2.31    1   23.33  ? 184 THR B CG2 1 
ATOM   2563 N  N   . TYR B 2 15  ? -27.13  -16.818 2.385   1   24.65  ? 185 TYR B N   1 
ATOM   2564 C  CA  . TYR B 2 15  ? -26.621 -16.233 3.61    1   22.24  ? 185 TYR B CA  1 
ATOM   2565 C  C   . TYR B 2 15  ? -26.379 -14.732 3.44    1   22.87  ? 185 TYR B C   1 
ATOM   2566 O  O   . TYR B 2 15  ? -26.674 -13.975 4.358   1   21.93  ? 185 TYR B O   1 
ATOM   2567 C  CB  . TYR B 2 15  ? -25.424 -17.043 4.1     1   23.85  ? 185 TYR B CB  1 
ATOM   2568 C  CG  . TYR B 2 15  ? -24.716 -16.376 5.27    1   26.45  ? 185 TYR B CG  1 
ATOM   2569 C  CD1 . TYR B 2 15  ? -25.292 -16.35  6.539   1   27.73  ? 185 TYR B CD1 1 
ATOM   2570 C  CD2 . TYR B 2 15  ? -23.49  -15.752 5.091   1   25.31  ? 185 TYR B CD2 1 
ATOM   2571 C  CE1 . TYR B 2 15  ? -24.669 -15.727 7.606   1   28.79  ? 185 TYR B CE1 1 
ATOM   2572 C  CE2 . TYR B 2 15  ? -22.861 -15.116 6.14    1   31.03  ? 185 TYR B CE2 1 
ATOM   2573 C  CZ  . TYR B 2 15  ? -23.447 -15.115 7.397   1   35.06  ? 185 TYR B CZ  1 
ATOM   2574 O  OH  . TYR B 2 15  ? -22.784 -14.492 8.407   1   42.88  ? 185 TYR B OH  1 
ATOM   2575 N  N   . LEU B 2 16  ? -25.861 -14.328 2.277   1   22.08  ? 186 LEU B N   1 
ATOM   2576 C  CA  . LEU B 2 16  ? -25.674 -12.88  2.003   1   24.19  ? 186 LEU B CA  1 
ATOM   2577 C  C   . LEU B 2 16  ? -27.057 -12.215 1.982   1   27.56  ? 186 LEU B C   1 
ATOM   2578 O  O   . LEU B 2 16  ? -27.197 -11.114 2.555   1   29.07  ? 186 LEU B O   1 
ATOM   2579 C  CB  . LEU B 2 16  ? -24.951 -12.691 0.672   1   27.26  ? 186 LEU B CB  1 
ATOM   2580 C  CG  . LEU B 2 16  ? -23.483 -13.124 0.635   1   24.93  ? 186 LEU B CG  1 
ATOM   2581 C  CD1 . LEU B 2 16  ? -22.818 -12.592 -0.622  1   21.7   ? 186 LEU B CD1 1 
ATOM   2582 C  CD2 . LEU B 2 16  ? -22.745 -12.66  1.879   1   21.44  ? 186 LEU B CD2 1 
ATOM   2583 N  N   . ARG B 2 17  ? -28.051 -12.872 1.401   1   27.36  ? 187 ARG B N   1 
ATOM   2584 C  CA  . ARG B 2 17  ? -29.408 -12.292 1.296   1   26.57  ? 187 ARG B CA  1 
ATOM   2585 C  C   . ARG B 2 17  ? -29.984 -12.035 2.692   1   27.75  ? 187 ARG B C   1 
ATOM   2586 O  O   . ARG B 2 17  ? -30.717 -11.057 2.865   1   31.16  ? 187 ARG B O   1 
ATOM   2587 C  CB  . ARG B 2 17  ? -30.299 -13.219 0.469   1   22.16  ? 187 ARG B CB  1 
ATOM   2588 C  CG  . ARG B 2 17  ? -30.05  -13.173 -1.029  1   21.79  ? 187 ARG B CG  1 
ATOM   2589 C  CD  . ARG B 2 17  ? -30.473 -11.852 -1.627  1   20.2   ? 187 ARG B CD  1 
ATOM   2590 N  NE  . ARG B 2 17  ? -31.923 -11.648 -1.576  1   21.01  ? 187 ARG B NE  1 
ATOM   2591 C  CZ  . ARG B 2 17  ? -32.812 -12.242 -2.355  1   22.05  ? 187 ARG B CZ  1 
ATOM   2592 N  NH1 . ARG B 2 17  ? -32.462 -12.704 -3.538  1   25.53  ? 187 ARG B NH1 1 
ATOM   2593 N  NH2 . ARG B 2 17  ? -34.058 -12.356 -1.952  1   19.21  ? 187 ARG B NH2 1 
ATOM   2594 N  N   . GLU B 2 18  ? -29.632 -12.848 3.677   1   26.86  ? 188 GLU B N   1 
ATOM   2595 C  CA  . GLU B 2 18  ? -30.167 -12.68  5.05    1   30.3   ? 188 GLU B CA  1 
ATOM   2596 C  C   . GLU B 2 18  ? -29.364 -11.608 5.796   1   31.27  ? 188 GLU B C   1 
ATOM   2597 O  O   . GLU B 2 18  ? -29.953 -10.864 6.594   1   27.81  ? 188 GLU B O   1 
ATOM   2598 C  CB  . GLU B 2 18  ? -30.135 -14.044 5.74    1   29.1   ? 188 GLU B CB  1 
ATOM   2599 C  CG  . GLU B 2 18  ? -30.72  -14.07  7.146   1   32.49  ? 188 GLU B CG  1 
ATOM   2600 C  CD  . GLU B 2 18  ? -30.695 -15.463 7.742   1   43.62  ? 188 GLU B CD  1 
ATOM   2601 O  OE1 . GLU B 2 18  ? -30.189 -16.386 7.07    1   44.24  ? 188 GLU B OE1 1 
ATOM   2602 O  OE2 . GLU B 2 18  ? -31.188 -15.627 8.874   1   45.08  ? 188 GLU B OE2 1 
ATOM   2603 N  N   . MET B 2 19  ? -28.071 -11.51  5.512   1   29.29  ? 189 MET B N   1 
ATOM   2604 C  CA  . MET B 2 19  ? -27.184 -10.557 6.216   1   29.89  ? 189 MET B CA  1 
ATOM   2605 C  C   . MET B 2 19  ? -27.309 -9.148  5.625   1   31.23  ? 189 MET B C   1 
ATOM   2606 O  O   . MET B 2 19  ? -27.011 -8.197  6.343   1   32.3   ? 189 MET B O   1 
ATOM   2607 C  CB  . MET B 2 19  ? -25.737 -11.04  6.117   1   28.97  ? 189 MET B CB  1 
ATOM   2608 C  CG  . MET B 2 19  ? -25.515 -12.409 6.686   1   33.97  ? 189 MET B CG  1 
ATOM   2609 S  SD  . MET B 2 19  ? -25.251 -12.376 8.465   1   40.58  ? 189 MET B SD  1 
ATOM   2610 C  CE  . MET B 2 19  ? -26.762 -13.143 9.06    1   41.96  ? 189 MET B CE  1 
ATOM   2611 N  N   . GLU B 2 20  ? -27.752 -9.029  4.378   1   27.06  ? 190 GLU B N   1 
ATOM   2612 C  CA  . GLU B 2 20  ? -27.965 -7.684  3.799   1   27.48  ? 190 GLU B CA  1 
ATOM   2613 C  C   . GLU B 2 20  ? -29.094 -7.025  4.583   1   30.86  ? 190 GLU B C   1 
ATOM   2614 O  O   . GLU B 2 20  ? -29.028 -5.81   4.793   1   34.92  ? 190 GLU B O   1 
ATOM   2615 C  CB  . GLU B 2 20  ? -28.217 -7.759  2.296   1   23.08  ? 190 GLU B CB  1 
ATOM   2616 C  CG  . GLU B 2 20  ? -29.646 -8.071  1.887   1   26.78  ? 190 GLU B CG  1 
ATOM   2617 C  CD  . GLU B 2 20  ? -29.661 -8.062  0.379   1   29.07  ? 190 GLU B CD  1 
ATOM   2618 O  OE1 . GLU B 2 20  ? -28.848 -7.325  -0.196  1   27.11  ? 190 GLU B OE1 1 
ATOM   2619 O  OE2 . GLU B 2 20  ? -30.468 -8.789  -0.212  1   25.94  ? 190 GLU B OE2 1 
ATOM   2620 N  N   . VAL B 2 21  ? -30.067 -7.821  5.01    1   28.76  ? 191 VAL B N   1 
ATOM   2621 C  CA  . VAL B 2 21  ? -31.167 -7.297  5.796   1   28.06  ? 191 VAL B CA  1 
ATOM   2622 C  C   . VAL B 2 21  ? -30.673 -6.883  7.187   1   30.13  ? 191 VAL B C   1 
ATOM   2623 O  O   . VAL B 2 21  ? -31.127 -5.883  7.737   1   31.27  ? 191 VAL B O   1 
ATOM   2624 C  CB  . VAL B 2 21  ? -32.332 -8.305  5.869   1   25.18  ? 191 VAL B CB  1 
ATOM   2625 C  CG1 . VAL B 2 21  ? -33.456 -7.78   6.738   1   20.19  ? 191 VAL B CG1 1 
ATOM   2626 C  CG2 . VAL B 2 21  ? -32.859 -8.707  4.487   1   22.72  ? 191 VAL B CG2 1 
ATOM   2627 N  N   . LYS B 2 22  ? -29.751 -7.661  7.759   1   33.75  ? 192 LYS B N   1 
ATOM   2628 C  CA  . LYS B 2 22  ? -29.223 -7.426  9.092   1   35.61  ? 192 LYS B CA  1 
ATOM   2629 C  C   . LYS B 2 22  ? -28.319 -6.192  9.065   1   39.43  ? 192 LYS B C   1 
ATOM   2630 O  O   . LYS B 2 22  ? -28.327 -5.401  9.994   1   41.62  ? 192 LYS B O   1 
ATOM   2631 C  CB  . LYS B 2 22  ? -28.438 -8.67   9.528   1   41.85  ? 192 LYS B CB  1 
ATOM   2632 C  CG  . LYS B 2 22  ? -27.85  -8.682  10.923  1   60.29  ? 192 LYS B CG  1 
ATOM   2633 C  CD  . LYS B 2 22  ? -27.068 -9.917  11.363  1   66.22  ? 192 LYS B CD  1 
ATOM   2634 C  CE  . LYS B 2 22  ? -25.769 -10.087 10.618  1   65.13  ? 192 LYS B CE  1 
ATOM   2635 N  NZ  . LYS B 2 22  ? -24.822 -8.999  10.9    1   69.05  ? 192 LYS B NZ  1 
ATOM   2636 N  N   . CYS B 2 23  ? -27.552 -6.014  7.98    1   41.89  ? 193 CYS B N   1 
ATOM   2637 C  CA  . CYS B 2 23  ? -26.544 -4.961  7.855   1   41.64  ? 193 CYS B CA  1 
ATOM   2638 C  C   . CYS B 2 23  ? -27.097 -3.713  7.159   1   40.97  ? 193 CYS B C   1 
ATOM   2639 O  O   . CYS B 2 23  ? -26.317 -2.87   6.697   1   39.45  ? 193 CYS B O   1 
ATOM   2640 C  CB  . CYS B 2 23  ? -25.296 -5.439  7.102   1   39.3   ? 193 CYS B CB  1 
ATOM   2641 S  SG  . CYS B 2 23  ? -24.278 -6.636  8.023   1   45.55  ? 193 CYS B SG  1 
ATOM   2642 N  N   . LYS B 2 24  ? -28.432 -3.58   7.093   1   37.07  ? 194 LYS B N   1 
ATOM   2643 C  CA  . LYS B 2 24  ? -29.038 -2.493  6.331   1   35.06  ? 194 LYS B CA  1 
ATOM   2644 C  C   . LYS B 2 24  ? -29.084 -1.216  7.184   1   35.2   ? 194 LYS B C   1 
ATOM   2645 O  O   . LYS B 2 24  ? -29.326 -1.256  8.389   1   32.81  ? 194 LYS B O   1 
ATOM   2646 C  CB  . LYS B 2 24  ? -30.445 -2.899  5.883   1   35.46  ? 194 LYS B CB  1 
ATOM   2647 C  CG  . LYS B 2 24  ? -30.944 -2.117  4.707   1   38.81  ? 194 LYS B CG  1 
ATOM   2648 C  CD  . LYS B 2 24  ? -32.453 -2.067  4.546   1   43.69  ? 194 LYS B CD  1 
ATOM   2649 C  CE  . LYS B 2 24  ? -32.803 -1.222  3.344   1   48.62  ? 194 LYS B CE  1 
ATOM   2650 N  NZ  . LYS B 2 24  ? -34.259 -1.112  3.18    1   49.96  ? 194 LYS B NZ  1 
ATOM   2651 N  N   . PRO B 2 25  ? -28.798 -0.024  6.617   1   34.64  ? 195 PRO B N   1 
ATOM   2652 C  CA  . PRO B 2 25  ? -28.94  1.221   7.369   1   31.1   ? 195 PRO B CA  1 
ATOM   2653 C  C   . PRO B 2 25  ? -30.41  1.574   7.452   1   32.45  ? 195 PRO B C   1 
ATOM   2654 O  O   . PRO B 2 25  ? -31.201 1.012   6.702   1   37.03  ? 195 PRO B O   1 
ATOM   2655 C  CB  . PRO B 2 25  ? -28.175 2.281   6.548   1   32.64  ? 195 PRO B CB  1 
ATOM   2656 C  CG  . PRO B 2 25  ? -27.475 1.509   5.433   1   33.23  ? 195 PRO B CG  1 
ATOM   2657 C  CD  . PRO B 2 25  ? -28.198 0.18    5.285   1   34.73  ? 195 PRO B CD  1 
ATOM   2658 N  N   . LYS B 2 26  ? -30.732 2.532   8.335   1   33.07  ? 196 LYS B N   1 
ATOM   2659 C  CA  . LYS B 2 26  ? -32.043 3.153   8.449   1   34.54  ? 196 LYS B CA  1 
ATOM   2660 C  C   . LYS B 2 26  ? -32.301 3.942   7.177   1   34.14  ? 196 LYS B C   1 
ATOM   2661 O  O   . LYS B 2 26  ? -31.466 4.769   6.845   1   34.78  ? 196 LYS B O   1 
ATOM   2662 C  CB  . LYS B 2 26  ? -32.113 4.074   9.679   1   37.29  ? 196 LYS B CB  1 
ATOM   2663 C  CG  . LYS B 2 26  ? -32.078 3.334   11.025  1   46.75  ? 196 LYS B CG  1 
ATOM   2664 C  CD  . LYS B 2 26  ? -32.002 4.093   12.356  1   57.25  ? 196 LYS B CD  1 
ATOM   2665 C  CE  . LYS B 2 26  ? -33.166 4.987   12.778  1   62.78  ? 196 LYS B CE  1 
ATOM   2666 N  NZ  . LYS B 2 26  ? -33.067 5.593   14.12   1   56.98  ? 196 LYS B NZ  1 
ATOM   2667 N  N   . VAL B 2 27  ? -33.434 3.693   6.496   1   35.48  ? 197 VAL B N   1 
ATOM   2668 C  CA  . VAL B 2 27  ? -33.776 4.371   5.248   1   37.75  ? 197 VAL B CA  1 
ATOM   2669 C  C   . VAL B 2 27  ? -33.799 5.893   5.426   1   42.26  ? 197 VAL B C   1 
ATOM   2670 O  O   . VAL B 2 27  ? -33.396 6.657   4.544   1   48.42  ? 197 VAL B O   1 
ATOM   2671 C  CB  . VAL B 2 27  ? -35.097 3.915   4.602   1   34.05  ? 197 VAL B CB  1 
ATOM   2672 C  CG1 . VAL B 2 27  ? -35.371 4.648   3.293   1   27.61  ? 197 VAL B CG1 1 
ATOM   2673 C  CG2 . VAL B 2 27  ? -35.133 2.409   4.378   1   40.32  ? 197 VAL B CG2 1 
ATOM   2674 N  N   . GLY B 2 28  ? -34.317 6.377   6.544   1   37.52  ? 198 GLY B N   1 
ATOM   2675 C  CA  . GLY B 2 28  ? -34.505 7.823   6.568   1   47.58  ? 198 GLY B CA  1 
ATOM   2676 C  C   . GLY B 2 28  ? -33.675 8.487   7.661   1   46.89  ? 198 GLY B C   1 
ATOM   2677 O  O   . GLY B 2 28  ? -34.22  9.215   8.495   1   49.34  ? 198 GLY B O   1 
ATOM   2678 N  N   . TYR B 2 29  ? -32.368 8.206   7.643   1   41.06  ? 199 TYR B N   1 
ATOM   2679 C  CA  . TYR B 2 29  ? -31.536 8.536   8.784   1   35.52  ? 199 TYR B CA  1 
ATOM   2680 C  C   . TYR B 2 29  ? -31.172 10.006  8.666   1   35.89  ? 199 TYR B C   1 
ATOM   2681 O  O   . TYR B 2 29  ? -31.002 10.676  9.687   1   35.27  ? 199 TYR B O   1 
ATOM   2682 C  CB  . TYR B 2 29  ? -30.369 7.57    9.017   1   30.73  ? 199 TYR B CB  1 
ATOM   2683 C  CG  . TYR B 2 29  ? -29.144 7.731   8.133   1   28.08  ? 199 TYR B CG  1 
ATOM   2684 C  CD1 . TYR B 2 29  ? -28.327 8.846   8.261   1   27.84  ? 199 TYR B CD1 1 
ATOM   2685 C  CD2 . TYR B 2 29  ? -28.75  6.732   7.247   1   27.85  ? 199 TYR B CD2 1 
ATOM   2686 C  CE1 . TYR B 2 29  ? -27.194 9.002   7.477   1   28.86  ? 199 TYR B CE1 1 
ATOM   2687 C  CE2 . TYR B 2 29  ? -27.611 6.868   6.464   1   27.87  ? 199 TYR B CE2 1 
ATOM   2688 C  CZ  . TYR B 2 29  ? -26.842 8.014   6.572   1   28.45  ? 199 TYR B CZ  1 
ATOM   2689 O  OH  . TYR B 2 29  ? -25.722 8.181   5.833   1   29.98  ? 199 TYR B OH  1 
ATOM   2690 N  N   . MET B 2 30  ? -31.148 10.508  7.425   1   31.79  ? 200 MET B N   1 
ATOM   2691 C  CA  . MET B 2 30  ? -30.558 11.815  7.212   1   33.76  ? 200 MET B CA  1 
ATOM   2692 C  C   . MET B 2 30  ? -31.503 12.923  7.684   1   33.44  ? 200 MET B C   1 
ATOM   2693 O  O   . MET B 2 30  ? -31.05  13.998  8.064   1   32.7   ? 200 MET B O   1 
ATOM   2694 C  CB  . MET B 2 30  ? -30.112 11.973  5.759   1   33.99  ? 200 MET B CB  1 
ATOM   2695 C  CG  . MET B 2 30  ? -29.143 13.101  5.561   1   31.46  ? 200 MET B CG  1 
ATOM   2696 S  SD  . MET B 2 30  ? -27.599 12.786  6.431   1   35.14  ? 200 MET B SD  1 
ATOM   2697 C  CE  . MET B 2 30  ? -26.675 11.908  5.165   1   41.14  ? 200 MET B CE  1 
ATOM   2698 N  N   . LYS B 2 31  ? -32.811 12.643  7.681   1   34.7   ? 201 LYS B N   1 
ATOM   2699 C  CA  . LYS B 2 31  ? -33.797 13.544  8.249   1   34.7   ? 201 LYS B CA  1 
ATOM   2700 C  C   . LYS B 2 31  ? -33.542 13.716  9.745   1   34.88  ? 201 LYS B C   1 
ATOM   2701 O  O   . LYS B 2 31  ? -33.684 14.815  10.265  1   39.15  ? 201 LYS B O   1 
ATOM   2702 C  CB  . LYS B 2 31  ? -35.223 13.028  8.035   1   38.1   ? 201 LYS B CB  1 
ATOM   2703 C  CG  . LYS B 2 31  ? -35.733 12.973  6.604   1   45.95  ? 201 LYS B CG  1 
ATOM   2704 C  CD  . LYS B 2 31  ? -36.875 11.971  6.389   1   56.08  ? 201 LYS B CD  1 
ATOM   2705 C  CE  . LYS B 2 31  ? -37.095 11.549  4.948   1   61.66  ? 201 LYS B CE  1 
ATOM   2706 N  NZ  . LYS B 2 31  ? -37.105 10.083  4.783   1   62.33  ? 201 LYS B NZ  1 
ATOM   2707 N  N   . LYS B 2 32  ? -33.15  12.637  10.433  1   35.96  ? 202 LYS B N   1 
ATOM   2708 C  CA  . LYS B 2 32  ? -32.909 12.68   11.871  1   37.53  ? 202 LYS B CA  1 
ATOM   2709 C  C   . LYS B 2 32  ? -31.495 13.173  12.176  1   33.41  ? 202 LYS B C   1 
ATOM   2710 O  O   . LYS B 2 32  ? -31.112 13.219  13.335  1   32.08  ? 202 LYS B O   1 
ATOM   2711 C  CB  . LYS B 2 32  ? -33.061 11.315  12.563  1   44.97  ? 202 LYS B CB  1 
ATOM   2712 C  CG  . LYS B 2 32  ? -34.451 10.676  12.625  1   50.04  ? 202 LYS B CG  1 
ATOM   2713 C  CD  . LYS B 2 32  ? -34.452 9.316   13.316  1   58.81  ? 202 LYS B CD  1 
ATOM   2714 C  CE  . LYS B 2 32  ? -35.786 8.642   13.433  1   63.45  ? 202 LYS B CE  1 
ATOM   2715 N  NZ  . LYS B 2 32  ? -35.66  7.34    14.089  1   73.56  ? 202 LYS B NZ  1 
ATOM   2716 N  N   . GLN B 2 33  ? -30.697 13.473  11.145  1   30.37  ? 203 GLN B N   1 
ATOM   2717 C  CA  . GLN B 2 33  ? -29.383 14.065  11.348  1   28.49  ? 203 GLN B CA  1 
ATOM   2718 C  C   . GLN B 2 33  ? -29.522 15.59   11.322  1   27.21  ? 203 GLN B C   1 
ATOM   2719 O  O   . GLN B 2 33  ? -29.774 16.176  10.266  1   28.53  ? 203 GLN B O   1 
ATOM   2720 C  CB  . GLN B 2 33  ? -28.387 13.555  10.304  1   25.1   ? 203 GLN B CB  1 
ATOM   2721 C  CG  . GLN B 2 33  ? -27.884 12.144  10.562  1   23.4   ? 203 GLN B CG  1 
ATOM   2722 C  CD  . GLN B 2 33  ? -26.791 12.055  11.6    1   24.84  ? 203 GLN B CD  1 
ATOM   2723 O  OE1 . GLN B 2 33  ? -26.323 13.06   12.144  1   26.76  ? 203 GLN B OE1 1 
ATOM   2724 N  NE2 . GLN B 2 33  ? -26.373 10.831  11.886  1   24.88  ? 203 GLN B NE2 1 
ATOM   2725 N  N   . PRO B 2 34  ? -29.394 16.268  12.487  1   25.83  ? 204 PRO B N   1 
ATOM   2726 C  CA  . PRO B 2 34  ? -29.594 17.713  12.58   1   25.01  ? 204 PRO B CA  1 
ATOM   2727 C  C   . PRO B 2 34  ? -28.667 18.588  11.748  1   25.4   ? 204 PRO B C   1 
ATOM   2728 O  O   . PRO B 2 34  ? -29.1   19.627  11.265  1   29.8   ? 204 PRO B O   1 
ATOM   2729 C  CB  . PRO B 2 34  ? -29.493 18.029  14.089  1   23.04  ? 204 PRO B CB  1 
ATOM   2730 C  CG  . PRO B 2 34  ? -28.756 16.856  14.677  1   23.89  ? 204 PRO B CG  1 
ATOM   2731 C  CD  . PRO B 2 34  ? -29.12  15.666  13.805  1   25.02  ? 204 PRO B CD  1 
ATOM   2732 N  N   . ASP B 2 35  ? -27.415 18.162  11.566  1   26.23  ? 205 ASP B N   1 
ATOM   2733 C  CA  . ASP B 2 35  ? -26.4   19.046  11.017  1   26.69  ? 205 ASP B CA  1 
ATOM   2734 C  C   . ASP B 2 35  ? -25.756 18.558  9.72    1   28.72  ? 205 ASP B C   1 
ATOM   2735 O  O   . ASP B 2 35  ? -24.875 19.242  9.208   1   32.17  ? 205 ASP B O   1 
ATOM   2736 C  CB  . ASP B 2 35  ? -25.269 19.261  12.003  1   28.06  ? 205 ASP B CB  1 
ATOM   2737 C  CG  . ASP B 2 35  ? -24.428 20.487  11.709  1   27.28  ? 205 ASP B CG  1 
ATOM   2738 O  OD1 . ASP B 2 35  ? -25.02  21.559  11.544  1   28.6   ? 205 ASP B OD1 1 
ATOM   2739 O  OD2 . ASP B 2 35  ? -23.205 20.352  11.625  1   28.04  ? 205 ASP B OD2 1 
ATOM   2740 N  N   . ILE B 2 36  ? -26.163 17.39   9.202   1   30.44  ? 206 ILE B N   1 
ATOM   2741 C  CA  . ILE B 2 36  ? -25.646 16.87   7.942   1   28.93  ? 206 ILE B CA  1 
ATOM   2742 C  C   . ILE B 2 36  ? -26.789 16.436  7.022   1   32.06  ? 206 ILE B C   1 
ATOM   2743 O  O   . ILE B 2 36  ? -27.923 16.183  7.452   1   31.73  ? 206 ILE B O   1 
ATOM   2744 C  CB  . ILE B 2 36  ? -24.61  15.748  8.138   1   28.93  ? 206 ILE B CB  1 
ATOM   2745 C  CG1 . ILE B 2 36  ? -25.197 14.495  8.803   1   27.54  ? 206 ILE B CG1 1 
ATOM   2746 C  CG2 . ILE B 2 36  ? -23.368 16.265  8.866   1   29.79  ? 206 ILE B CG2 1 
ATOM   2747 C  CD1 . ILE B 2 36  ? -24.182 13.367  9.01    1   27.82  ? 206 ILE B CD1 1 
ATOM   2748 N  N   . THR B 2 37  ? -26.446 16.382  5.726   1   32.86  ? 207 THR B N   1 
ATOM   2749 C  CA  . THR B 2 37  ? -27.391 16.306  4.621   1   31.46  ? 207 THR B CA  1 
ATOM   2750 C  C   . THR B 2 37  ? -26.901 15.253  3.641   1   31.71  ? 207 THR B C   1 
ATOM   2751 O  O   . THR B 2 37  ? -25.74  14.829  3.704   1   30.3   ? 207 THR B O   1 
ATOM   2752 C  CB  . THR B 2 37  ? -27.473 17.645  3.886   1   31.34  ? 207 THR B CB  1 
ATOM   2753 O  OG1 . THR B 2 37  ? -26.173 17.81   3.322   1   32.05  ? 207 THR B OG1 1 
ATOM   2754 C  CG2 . THR B 2 37  ? -27.835 18.823  4.77    1   24.99  ? 207 THR B CG2 1 
ATOM   2755 N  N   . ASN B 2 38  ? -27.803 14.882  2.723   1   33.07  ? 208 ASN B N   1 
ATOM   2756 C  CA  . ASN B 2 38  ? -27.501 13.917  1.677   1   32.58  ? 208 ASN B CA  1 
ATOM   2757 C  C   . ASN B 2 38  ? -26.353 14.436  0.822   1   31.96  ? 208 ASN B C   1 
ATOM   2758 O  O   . ASN B 2 38  ? -25.496 13.678  0.372   1   36.29  ? 208 ASN B O   1 
ATOM   2759 C  CB  . ASN B 2 38  ? -28.732 13.596  0.843   1   30.57  ? 208 ASN B CB  1 
ATOM   2760 C  CG  . ASN B 2 38  ? -29.687 12.712  1.607   1   31.22  ? 208 ASN B CG  1 
ATOM   2761 O  OD1 . ASN B 2 38  ? -29.244 11.87   2.406   1   33.45  ? 208 ASN B OD1 1 
ATOM   2762 N  ND2 . ASN B 2 38  ? -30.979 12.849  1.339   1   26.54  ? 208 ASN B ND2 1 
ATOM   2763 N  N   . SER B 2 39  ? -26.303 15.75   0.672   1   28.4   ? 209 SER B N   1 
ATOM   2764 C  CA  . SER B 2 39  ? -25.277 16.355  -0.155  1   32.62  ? 209 SER B CA  1 
ATOM   2765 C  C   . SER B 2 39  ? -23.888 16.206  0.48    1   29.97  ? 209 SER B C   1 
ATOM   2766 O  O   . SER B 2 39  ? -22.909 15.95   -0.215  1   30.09  ? 209 SER B O   1 
ATOM   2767 C  CB  . SER B 2 39  ? -25.659 17.782  -0.46   1   32.3   ? 209 SER B CB  1 
ATOM   2768 O  OG  . SER B 2 39  ? -24.497 18.506  -0.797  1   40.3   ? 209 SER B OG  1 
ATOM   2769 N  N   . MET B 2 40  ? -23.801 16.328  1.809   1   30.24  ? 210 MET B N   1 
ATOM   2770 C  CA  . MET B 2 40  ? -22.524 16.243  2.501   1   29.36  ? 210 MET B CA  1 
ATOM   2771 C  C   . MET B 2 40  ? -22     14.818  2.427   1   30.4   ? 210 MET B C   1 
ATOM   2772 O  O   . MET B 2 40  ? -20.793 14.604  2.315   1   35.61  ? 210 MET B O   1 
ATOM   2773 C  CB  . MET B 2 40  ? -22.653 16.646  3.973   1   30.16  ? 210 MET B CB  1 
ATOM   2774 C  CG  . MET B 2 40  ? -22.964 18.121  4.144   1   31.46  ? 210 MET B CG  1 
ATOM   2775 S  SD  . MET B 2 40  ? -23.113 18.513  5.892   1   33.66  ? 210 MET B SD  1 
ATOM   2776 C  CE  . MET B 2 40  ? -23.804 20.175  5.821   1   29.95  ? 210 MET B CE  1 
ATOM   2777 N  N   . ARG B 2 41  ? -22.922 13.86   2.515   1   26.89  ? 211 ARG B N   1 
ATOM   2778 C  CA  . ARG B 2 41  ? -22.572 12.456  2.405   1   27.42  ? 211 ARG B CA  1 
ATOM   2779 C  C   . ARG B 2 41  ? -22.034 12.196  0.999   1   24.76  ? 211 ARG B C   1 
ATOM   2780 O  O   . ARG B 2 41  ? -21.154 11.37   0.81    1   24.62  ? 211 ARG B O   1 
ATOM   2781 C  CB  . ARG B 2 41  ? -23.806 11.598  2.734   1   28.05  ? 211 ARG B CB  1 
ATOM   2782 C  CG  . ARG B 2 41  ? -23.585 10.096  2.708   1   25.38  ? 211 ARG B CG  1 
ATOM   2783 C  CD  . ARG B 2 41  ? -24.903 9.359   2.822   1   29.33  ? 211 ARG B CD  1 
ATOM   2784 N  NE  . ARG B 2 41  ? -24.812 7.92    2.517   1   29.74  ? 211 ARG B NE  1 
ATOM   2785 C  CZ  . ARG B 2 41  ? -24.528 7.442   1.302   1   30.61  ? 211 ARG B CZ  1 
ATOM   2786 N  NH1 . ARG B 2 41  ? -24.514 8.287   0.264   1   25.11  ? 211 ARG B NH1 1 
ATOM   2787 N  NH2 . ARG B 2 41  ? -24.238 6.143   1.145   1   26.8   ? 211 ARG B NH2 1 
ATOM   2788 N  N   . ALA B 2 42  ? -22.622 12.867  0.009   1   24.2   ? 212 ALA B N   1 
ATOM   2789 C  CA  . ALA B 2 42  ? -22.282 12.602  -1.371  1   25.18  ? 212 ALA B CA  1 
ATOM   2790 C  C   . ALA B 2 42  ? -20.858 13.095  -1.573  1   25.18  ? 212 ALA B C   1 
ATOM   2791 O  O   . ALA B 2 42  ? -20.022 12.428  -2.185  1   25.1   ? 212 ALA B O   1 
ATOM   2792 C  CB  . ALA B 2 42  ? -23.271 13.289  -2.289  1   25.64  ? 212 ALA B CB  1 
ATOM   2793 N  N   . ILE B 2 43  ? -20.588 14.259  -0.991  1   23.26  ? 213 ILE B N   1 
ATOM   2794 C  CA  . ILE B 2 43  ? -19.242 14.776  -1.039  1   22.62  ? 213 ILE B CA  1 
ATOM   2795 C  C   . ILE B 2 43  ? -18.318 13.767  -0.348  1   23.8   ? 213 ILE B C   1 
ATOM   2796 O  O   . ILE B 2 43  ? -17.248 13.452  -0.877  1   23.85  ? 213 ILE B O   1 
ATOM   2797 C  CB  . ILE B 2 43  ? -19.208 16.199  -0.458  1   22.71  ? 213 ILE B CB  1 
ATOM   2798 C  CG1 . ILE B 2 43  ? -20.089 17.16   -1.298  1   20.01  ? 213 ILE B CG1 1 
ATOM   2799 C  CG2 . ILE B 2 43  ? -17.769 16.713  -0.337  1   22.73  ? 213 ILE B CG2 1 
ATOM   2800 C  CD1 . ILE B 2 43  ? -20.295 18.523  -0.664  1   16.35  ? 213 ILE B CD1 1 
ATOM   2801 N  N   . LEU B 2 44  ? -18.75  13.205  0.793   1   22.74  ? 214 LEU B N   1 
ATOM   2802 C  CA  . LEU B 2 44  ? -17.886 12.313  1.558   1   24.08  ? 214 LEU B CA  1 
ATOM   2803 C  C   . LEU B 2 44  ? -17.569 11.046  0.749   1   28.18  ? 214 LEU B C   1 
ATOM   2804 O  O   . LEU B 2 44  ? -16.399 10.67   0.572   1   29.64  ? 214 LEU B O   1 
ATOM   2805 C  CB  . LEU B 2 44  ? -18.5   12.012  2.922   1   21.03  ? 214 LEU B CB  1 
ATOM   2806 C  CG  . LEU B 2 44  ? -17.81  10.912  3.734   1   23     ? 214 LEU B CG  1 
ATOM   2807 C  CD1 . LEU B 2 44  ? -16.438 11.329  4.253   1   20.45  ? 214 LEU B CD1 1 
ATOM   2808 C  CD2 . LEU B 2 44  ? -18.692 10.404  4.886   1   23.41  ? 214 LEU B CD2 1 
ATOM   2809 N  N   . VAL B 2 45  ? -18.624 10.406  0.23    1   26.75  ? 215 VAL B N   1 
ATOM   2810 C  CA  . VAL B 2 45  ? -18.465 9.166   -0.503  1   27.97  ? 215 VAL B CA  1 
ATOM   2811 C  C   . VAL B 2 45  ? -17.609 9.417   -1.739  1   29.5   ? 215 VAL B C   1 
ATOM   2812 O  O   . VAL B 2 45  ? -16.749 8.605   -2.084  1   31.73  ? 215 VAL B O   1 
ATOM   2813 C  CB  . VAL B 2 45  ? -19.829 8.568   -0.88   1   29.33  ? 215 VAL B CB  1 
ATOM   2814 C  CG1 . VAL B 2 45  ? -19.657 7.269   -1.646  1   28.55  ? 215 VAL B CG1 1 
ATOM   2815 C  CG2 . VAL B 2 45  ? -20.686 8.358   0.363   1   27.02  ? 215 VAL B CG2 1 
ATOM   2816 N  N   . ASP B 2 46  ? -17.85  10.553  -2.402  1   27.46  ? 216 ASP B N   1 
ATOM   2817 C  CA  . ASP B 2 46  ? -17.112 10.881  -3.607  1   24.5   ? 216 ASP B CA  1 
ATOM   2818 C  C   . ASP B 2 46  ? -15.614 10.941  -3.308  1   23.74  ? 216 ASP B C   1 
ATOM   2819 O  O   . ASP B 2 46  ? -14.81  10.392  -4.055  1   26.28  ? 216 ASP B O   1 
ATOM   2820 C  CB  . ASP B 2 46  ? -17.628 12.165  -4.215  1   24.49  ? 216 ASP B CB  1 
ATOM   2821 C  CG  . ASP B 2 46  ? -16.877 12.579  -5.464  1   26.76  ? 216 ASP B CG  1 
ATOM   2822 O  OD1 . ASP B 2 46  ? -17.18  12.016  -6.523  1   30.77  ? 216 ASP B OD1 1 
ATOM   2823 O  OD2 . ASP B 2 46  ? -15.95  13.401  -5.34   1   27.33  ? 216 ASP B OD2 1 
ATOM   2824 N  N   . TRP B 2 47  ? -15.252 11.604  -2.208  1   20.72  ? 217 TRP B N   1 
ATOM   2825 C  CA  . TRP B 2 47  ? -13.885 11.654  -1.725  1   23     ? 217 TRP B CA  1 
ATOM   2826 C  C   . TRP B 2 47  ? -13.303 10.268  -1.405  1   28.03  ? 217 TRP B C   1 
ATOM   2827 O  O   . TRP B 2 47  ? -12.148 9.961   -1.748  1   31.14  ? 217 TRP B O   1 
ATOM   2828 C  CB  . TRP B 2 47  ? -13.884 12.537  -0.479  1   23.25  ? 217 TRP B CB  1 
ATOM   2829 C  CG  . TRP B 2 47  ? -12.551 12.612  0.195   1   23.28  ? 217 TRP B CG  1 
ATOM   2830 C  CD1 . TRP B 2 47  ? -11.44  13.264  -0.247  1   22.38  ? 217 TRP B CD1 1 
ATOM   2831 C  CD2 . TRP B 2 47  ? -12.21  12.049  1.473   1   23.92  ? 217 TRP B CD2 1 
ATOM   2832 N  NE1 . TRP B 2 47  ? -10.418 13.118  0.651   1   23.29  ? 217 TRP B NE1 1 
ATOM   2833 C  CE2 . TRP B 2 47  ? -10.864 12.392  1.722   1   24.97  ? 217 TRP B CE2 1 
ATOM   2834 C  CE3 . TRP B 2 47  ? -12.904 11.295  2.415   1   25.67  ? 217 TRP B CE3 1 
ATOM   2835 C  CZ2 . TRP B 2 47  ? -10.203 12.012  2.883   1   27.41  ? 217 TRP B CZ2 1 
ATOM   2836 C  CZ3 . TRP B 2 47  ? -12.248 10.91   3.564   1   27.43  ? 217 TRP B CZ3 1 
ATOM   2837 C  CH2 . TRP B 2 47  ? -10.927 11.279  3.797   1   29.4   ? 217 TRP B CH2 1 
ATOM   2838 N  N   . LEU B 2 48  ? -14.081 9.413   -0.726  1   25.88  ? 218 LEU B N   1 
ATOM   2839 C  CA  . LEU B 2 48  ? -13.591 8.074   -0.457  1   24.52  ? 218 LEU B CA  1 
ATOM   2840 C  C   . LEU B 2 48  ? -13.335 7.337   -1.769  1   26.13  ? 218 LEU B C   1 
ATOM   2841 O  O   . LEU B 2 48  ? -12.498 6.437   -1.808  1   28.61  ? 218 LEU B O   1 
ATOM   2842 C  CB  . LEU B 2 48  ? -14.6   7.326   0.408   1   26.02  ? 218 LEU B CB  1 
ATOM   2843 C  CG  . LEU B 2 48  ? -14.78  7.853   1.837   1   25.6   ? 218 LEU B CG  1 
ATOM   2844 C  CD1 . LEU B 2 48  ? -15.889 7.096   2.528   1   23.19  ? 218 LEU B CD1 1 
ATOM   2845 C  CD2 . LEU B 2 48  ? -13.462 7.755   2.597   1   25.09  ? 218 LEU B CD2 1 
ATOM   2846 N  N   . VAL B 2 49  ? -14.071 7.697   -2.829  1   25.09  ? 219 VAL B N   1 
ATOM   2847 C  CA  . VAL B 2 49  ? -13.856 7.09    -4.133  1   26.67  ? 219 VAL B CA  1 
ATOM   2848 C  C   . VAL B 2 49  ? -12.451 7.455   -4.599  1   29.94  ? 219 VAL B C   1 
ATOM   2849 O  O   . VAL B 2 49  ? -11.713 6.619   -5.139  1   29.63  ? 219 VAL B O   1 
ATOM   2850 C  CB  . VAL B 2 49  ? -14.926 7.515   -5.156  1   26.45  ? 219 VAL B CB  1 
ATOM   2851 C  CG1 . VAL B 2 49  ? -14.528 7.167   -6.587  1   21.54  ? 219 VAL B CG1 1 
ATOM   2852 C  CG2 . VAL B 2 49  ? -16.298 6.941   -4.797  1   26.78  ? 219 VAL B CG2 1 
ATOM   2853 N  N   . GLU B 2 50  ? -12.083 8.712   -4.325  1   30.37  ? 220 GLU B N   1 
ATOM   2854 C  CA  . GLU B 2 50  ? -10.777 9.226   -4.69   1   33.24  ? 220 GLU B CA  1 
ATOM   2855 C  C   . GLU B 2 50  ? -9.683  8.6     -3.831  1   31.8   ? 220 GLU B C   1 
ATOM   2856 O  O   . GLU B 2 50  ? -8.631  8.261   -4.358  1   33.73  ? 220 GLU B O   1 
ATOM   2857 C  CB  . GLU B 2 50  ? -10.708 10.736  -4.488  1   35.14  ? 220 GLU B CB  1 
ATOM   2858 C  CG  . GLU B 2 50  ? -11.196 11.513  -5.698  1   41.44  ? 220 GLU B CG  1 
ATOM   2859 C  CD  . GLU B 2 50  ? -11.019 12.997  -5.459  1   49.2   ? 220 GLU B CD  1 
ATOM   2860 O  OE1 . GLU B 2 50  ? -11.126 13.744  -6.463  1   58.79  ? 220 GLU B OE1 1 
ATOM   2861 O  OE2 . GLU B 2 50  ? -10.774 13.394  -4.288  1   47.04  ? 220 GLU B OE2 1 
ATOM   2862 N  N   . VAL B 2 51  ? -9.905  8.529   -2.511  1   27.8   ? 221 VAL B N   1 
ATOM   2863 C  CA  . VAL B 2 51  ? -8.938  7.906   -1.622  1   24.78  ? 221 VAL B CA  1 
ATOM   2864 C  C   . VAL B 2 51  ? -8.685  6.486   -2.122  1   26.11  ? 221 VAL B C   1 
ATOM   2865 O  O   . VAL B 2 51  ? -7.532  6.059   -2.226  1   25.18  ? 221 VAL B O   1 
ATOM   2866 C  CB  . VAL B 2 51  ? -9.46   7.938   -0.174  1   23     ? 221 VAL B CB  1 
ATOM   2867 C  CG1 . VAL B 2 51  ? -8.683  7.011   0.745   1   21.77  ? 221 VAL B CG1 1 
ATOM   2868 C  CG2 . VAL B 2 51  ? -9.487  9.364   0.371   1   23.55  ? 221 VAL B CG2 1 
ATOM   2869 N  N   . GLY B 2 52  ? -9.789  5.791   -2.449  1   26.72  ? 222 GLY B N   1 
ATOM   2870 C  CA  . GLY B 2 52  ? -9.769  4.463   -3.032  1   26.98  ? 222 GLY B CA  1 
ATOM   2871 C  C   . GLY B 2 52  ? -8.815  4.417   -4.216  1   30.33  ? 222 GLY B C   1 
ATOM   2872 O  O   . GLY B 2 52  ? -7.983  3.515   -4.283  1   32.93  ? 222 GLY B O   1 
ATOM   2873 N  N   . GLU B 2 53  ? -8.93   5.399   -5.122  1   31.6   ? 223 GLU B N   1 
ATOM   2874 C  CA  . GLU B 2 53  ? -8.102  5.453   -6.324  1   32.31  ? 223 GLU B CA  1 
ATOM   2875 C  C   . GLU B 2 53  ? -6.671  5.86    -5.983  1   29.73  ? 223 GLU B C   1 
ATOM   2876 O  O   . GLU B 2 53  ? -5.7    5.303   -6.494  1   30.31  ? 223 GLU B O   1 
ATOM   2877 C  CB  . GLU B 2 53  ? -8.732  6.28    -7.451  1   35.43  ? 223 GLU B CB  1 
ATOM   2878 C  CG  . GLU B 2 53  ? -10.027 5.677   -7.997  1   44.58  ? 223 GLU B CG  1 
ATOM   2879 C  CD  . GLU B 2 53  ? -9.958  4.25    -8.561  1   53.45  ? 223 GLU B CD  1 
ATOM   2880 O  OE1 . GLU B 2 53  ? -8.946  3.944   -9.243  1   59.8   ? 223 GLU B OE1 1 
ATOM   2881 O  OE2 . GLU B 2 53  ? -10.881 3.42    -8.347  1   54.24  ? 223 GLU B OE2 1 
ATOM   2882 N  N   . GLU B 2 54  ? -6.544  6.845   -5.099  1   34.38  ? 224 GLU B N   1 
ATOM   2883 C  CA  . GLU B 2 54  ? -5.239  7.339   -4.701  1   35.44  ? 224 GLU B CA  1 
ATOM   2884 C  C   . GLU B 2 54  ? -4.378  6.177   -4.2    1   35.63  ? 224 GLU B C   1 
ATOM   2885 O  O   . GLU B 2 54  ? -3.216  6.102   -4.576  1   34.62  ? 224 GLU B O   1 
ATOM   2886 C  CB  . GLU B 2 54  ? -5.388  8.457   -3.672  1   40.38  ? 224 GLU B CB  1 
ATOM   2887 C  CG  . GLU B 2 54  ? -4.069  8.895   -3.043  1   46.32  ? 224 GLU B CG  1 
ATOM   2888 C  CD  . GLU B 2 54  ? -3.151  9.609   -4.019  1   53.81  ? 224 GLU B CD  1 
ATOM   2889 O  OE1 . GLU B 2 54  ? -3.604  9.937   -5.141  1   49.54  ? 224 GLU B OE1 1 
ATOM   2890 O  OE2 . GLU B 2 54  ? -1.968  9.817   -3.659  1   60.65  ? 224 GLU B OE2 1 
ATOM   2891 N  N   . TYR B 2 55  ? -4.979  5.258   -3.43   1   33.61  ? 225 TYR B N   1 
ATOM   2892 C  CA  . TYR B 2 55  ? -4.207  4.141   -2.816  1   31.25  ? 225 TYR B CA  1 
ATOM   2893 C  C   . TYR B 2 55  ? -4.577  2.787   -3.431  1   29.15  ? 225 TYR B C   1 
ATOM   2894 O  O   . TYR B 2 55  ? -4.419  1.765   -2.728  1   25.02  ? 225 TYR B O   1 
ATOM   2895 C  CB  . TYR B 2 55  ? -4.482  4.12    -1.311  1   31.69  ? 225 TYR B CB  1 
ATOM   2896 C  CG  . TYR B 2 55  ? -3.946  5.325   -0.55   1   36.43  ? 225 TYR B CG  1 
ATOM   2897 C  CD1 . TYR B 2 55  ? -2.603  5.416   -0.208  1   39.73  ? 225 TYR B CD1 1 
ATOM   2898 C  CD2 . TYR B 2 55  ? -4.785  6.367   -0.172  1   42.05  ? 225 TYR B CD2 1 
ATOM   2899 C  CE1 . TYR B 2 55  ? -2.109  6.508   0.486   1   42.14  ? 225 TYR B CE1 1 
ATOM   2900 C  CE2 . TYR B 2 55  ? -4.302  7.465   0.521   1   40.89  ? 225 TYR B CE2 1 
ATOM   2901 C  CZ  . TYR B 2 55  ? -2.961  7.535   0.851   1   41.28  ? 225 TYR B CZ  1 
ATOM   2902 O  OH  . TYR B 2 55  ? -2.479  8.614   1.534   1   44.73  ? 225 TYR B OH  1 
ATOM   2903 N  N   . LYS B 2 56  ? -5.048  2.765   -4.681  1   28.62  ? 226 LYS B N   1 
ATOM   2904 C  CA  . LYS B 2 56  ? -5.35   1.484   -5.382  1   30.24  ? 226 LYS B CA  1 
ATOM   2905 C  C   . LYS B 2 56  ? -5.98   0.46    -4.423  1   32.31  ? 226 LYS B C   1 
ATOM   2906 O  O   . LYS B 2 56  ? -5.49   -0.69   -4.386  1   36.26  ? 226 LYS B O   1 
ATOM   2907 C  CB  . LYS B 2 56  ? -4.086  0.935   -6.055  1   35.54  ? 226 LYS B CB  1 
ATOM   2908 C  CG  . LYS B 2 56  ? -3.577  1.79    -7.209  1   54.31  ? 226 LYS B CG  1 
ATOM   2909 C  CD  . LYS B 2 56  ? -2.307  1.245   -7.852  1   72.28  ? 226 LYS B CD  1 
ATOM   2910 C  CE  . LYS B 2 56  ? -1.822  2.072   -9      1   89.74  ? 226 LYS B CE  1 
ATOM   2911 N  NZ  . LYS B 2 56  ? -0.588  1.527   -9.573  1   83.61  ? 226 LYS B NZ  1 
ATOM   2912 N  N   . LEU B 2 57  ? -7.02   0.851   -3.686  1   30.51  ? 227 LEU B N   1 
ATOM   2913 C  CA  . LEU B 2 57  ? -7.745  -0.044  -2.804  1   26.65  ? 227 LEU B CA  1 
ATOM   2914 C  C   . LEU B 2 57  ? -8.762  -0.777  -3.664  1   30.57  ? 227 LEU B C   1 
ATOM   2915 O  O   . LEU B 2 57  ? -9.113  -0.307  -4.748  1   36.02  ? 227 LEU B O   1 
ATOM   2916 C  CB  . LEU B 2 57  ? -8.46   0.739   -1.701  1   24.16  ? 227 LEU B CB  1 
ATOM   2917 C  CG  . LEU B 2 57  ? -7.596  1.646   -0.813  1   23.21  ? 227 LEU B CG  1 
ATOM   2918 C  CD1 . LEU B 2 57  ? -8.451  2.346   0.21    1   22.13  ? 227 LEU B CD1 1 
ATOM   2919 C  CD2 . LEU B 2 57  ? -6.511  0.876   -0.093  1   22.22  ? 227 LEU B CD2 1 
ATOM   2920 N  N   . GLN B 2 58  ? -9.263  -1.899  -3.143  1   27.44  ? 228 GLN B N   1 
ATOM   2921 C  CA  . GLN B 2 58  ? -10.294 -2.647  -3.826  1   25.23  ? 228 GLN B CA  1 
ATOM   2922 C  C   . GLN B 2 58  ? -11.594 -1.849  -3.814  1   27.15  ? 228 GLN B C   1 
ATOM   2923 O  O   . GLN B 2 58  ? -11.86  -1.094  -2.879  1   26.58  ? 228 GLN B O   1 
ATOM   2924 C  CB  . GLN B 2 58  ? -10.508 -3.974  -3.102  1   24.12  ? 228 GLN B CB  1 
ATOM   2925 C  CG  . GLN B 2 58  ? -9.345  -4.941  -3.209  1   26.77  ? 228 GLN B CG  1 
ATOM   2926 C  CD  . GLN B 2 58  ? -9.159  -5.405  -4.635  1   31.28  ? 228 GLN B CD  1 
ATOM   2927 O  OE1 . GLN B 2 58  ? -10.064 -5.993  -5.245  1   35     ? 228 GLN B OE1 1 
ATOM   2928 N  NE2 . GLN B 2 58  ? -8.007  -5.069  -5.192  1   25.64  ? 228 GLN B NE2 1 
ATOM   2929 N  N   . ASN B 2 59  ? -12.424 -2.08   -4.837  1   28.02  ? 229 ASN B N   1 
ATOM   2930 C  CA  . ASN B 2 59  ? -13.775 -1.556  -4.898  1   28.58  ? 229 ASN B CA  1 
ATOM   2931 C  C   . ASN B 2 59  ? -14.596 -2.11   -3.738  1   32.92  ? 229 ASN B C   1 
ATOM   2932 O  O   . ASN B 2 59  ? -15.501 -1.422  -3.228  1   37.59  ? 229 ASN B O   1 
ATOM   2933 C  CB  . ASN B 2 59  ? -14.445 -1.893  -6.225  1   30.87  ? 229 ASN B CB  1 
ATOM   2934 C  CG  . ASN B 2 59  ? -13.908 -1.09   -7.389  1   32     ? 229 ASN B CG  1 
ATOM   2935 O  OD1 . ASN B 2 59  ? -13.062 -0.208  -7.209  1   29.88  ? 229 ASN B OD1 1 
ATOM   2936 N  ND2 . ASN B 2 59  ? -14.394 -1.381  -8.589  1   30.9   ? 229 ASN B ND2 1 
ATOM   2937 N  N   . GLU B 2 60  ? -14.307 -3.371  -3.364  1   28.48  ? 230 GLU B N   1 
ATOM   2938 C  CA  . GLU B 2 60  ? -14.968 -3.972  -2.219  1   26.05  ? 230 GLU B CA  1 
ATOM   2939 C  C   . GLU B 2 60  ? -14.763 -3.072  -0.988  1   27.17  ? 230 GLU B C   1 
ATOM   2940 O  O   . GLU B 2 60  ? -15.686 -2.845  -0.195  1   23.53  ? 230 GLU B O   1 
ATOM   2941 C  CB  . GLU B 2 60  ? -14.458 -5.396  -2.02   1   24.7   ? 230 GLU B CB  1 
ATOM   2942 C  CG  . GLU B 2 60  ? -15.12  -6.138  -0.858  1   24.36  ? 230 GLU B CG  1 
ATOM   2943 C  CD  . GLU B 2 60  ? -16.622 -6.332  -0.978  1   26.48  ? 230 GLU B CD  1 
ATOM   2944 O  OE1 . GLU B 2 60  ? -17.21  -6.068  -2.043  1   30.08  ? 230 GLU B OE1 1 
ATOM   2945 O  OE2 . GLU B 2 60  ? -17.225 -6.736  0.013   1   27.92  ? 230 GLU B OE2 1 
ATOM   2946 N  N   . THR B 2 61  ? -13.546 -2.533  -0.846  1   25.97  ? 231 THR B N   1 
ATOM   2947 C  CA  . THR B 2 61  ? -13.205 -1.752  0.331   1   28.89  ? 231 THR B CA  1 
ATOM   2948 C  C   . THR B 2 61  ? -14.088 -0.503  0.4     1   31.28  ? 231 THR B C   1 
ATOM   2949 O  O   . THR B 2 61  ? -14.675 -0.205  1.44    1   27.39  ? 231 THR B O   1 
ATOM   2950 C  CB  . THR B 2 61  ? -11.711 -1.457  0.333   1   27.71  ? 231 THR B CB  1 
ATOM   2951 O  OG1 . THR B 2 61  ? -11.077 -2.713  0.099   1   26.37  ? 231 THR B OG1 1 
ATOM   2952 C  CG2 . THR B 2 61  ? -11.258 -0.874  1.654   1   28.59  ? 231 THR B CG2 1 
ATOM   2953 N  N   . LEU B 2 62  ? -14.236 0.172   -0.747  1   34.07  ? 232 LEU B N   1 
ATOM   2954 C  CA  . LEU B 2 62  ? -15.066 1.359   -0.842  1   29.58  ? 232 LEU B CA  1 
ATOM   2955 C  C   . LEU B 2 62  ? -16.467 0.993   -0.374  1   28.51  ? 232 LEU B C   1 
ATOM   2956 O  O   . LEU B 2 62  ? -16.988 1.627   0.535   1   29.94  ? 232 LEU B O   1 
ATOM   2957 C  CB  . LEU B 2 62  ? -15.054 1.863   -2.287  1   29.82  ? 232 LEU B CB  1 
ATOM   2958 C  CG  . LEU B 2 62  ? -16.062 2.97    -2.619  1   31.25  ? 232 LEU B CG  1 
ATOM   2959 C  CD1 . LEU B 2 62  ? -15.889 4.257   -1.803  1   25.38  ? 232 LEU B CD1 1 
ATOM   2960 C  CD2 . LEU B 2 62  ? -16.023 3.245   -4.118  1   33.5   ? 232 LEU B CD2 1 
ATOM   2961 N  N   . HIS B 2 63  ? -17.041 -0.052  -0.988  1   27.43  ? 233 HIS B N   1 
ATOM   2962 C  CA  . HIS B 2 63  ? -18.38  -0.532  -0.654  1   25.59  ? 233 HIS B CA  1 
ATOM   2963 C  C   . HIS B 2 63  ? -18.558 -0.834  0.843   1   27.29  ? 233 HIS B C   1 
ATOM   2964 O  O   . HIS B 2 63  ? -19.6   -0.484  1.403   1   32.14  ? 233 HIS B O   1 
ATOM   2965 C  CB  . HIS B 2 63  ? -18.753 -1.765  -1.49   1   26.14  ? 233 HIS B CB  1 
ATOM   2966 C  CG  . HIS B 2 63  ? -19.32  -1.444  -2.834  1   31.49  ? 233 HIS B CG  1 
ATOM   2967 N  ND1 . HIS B 2 63  ? -18.533 -1.132  -3.932  1   31.29  ? 233 HIS B ND1 1 
ATOM   2968 C  CD2 . HIS B 2 63  ? -20.604 -1.33   -3.233  1   29.78  ? 233 HIS B CD2 1 
ATOM   2969 C  CE1 . HIS B 2 63  ? -19.324 -0.83   -4.956  1   30.32  ? 233 HIS B CE1 1 
ATOM   2970 N  NE2 . HIS B 2 63  ? -20.58  -0.967  -4.565  1   31.1   ? 233 HIS B NE2 1 
ATOM   2971 N  N   . LEU B 2 64  ? -17.6   -1.53   1.478   1   23.59  ? 234 LEU B N   1 
ATOM   2972 C  CA  . LEU B 2 64  ? -17.704 -1.846  2.89    1   24.69  ? 234 LEU B CA  1 
ATOM   2973 C  C   . LEU B 2 64  ? -17.744 -0.54   3.674   1   27.42  ? 234 LEU B C   1 
ATOM   2974 O  O   . LEU B 2 64  ? -18.538 -0.387  4.606   1   27.69  ? 234 LEU B O   1 
ATOM   2975 C  CB  . LEU B 2 64  ? -16.536 -2.725  3.35    1   26.04  ? 234 LEU B CB  1 
ATOM   2976 C  CG  . LEU B 2 64  ? -16.524 -4.165  2.819   1   26.79  ? 234 LEU B CG  1 
ATOM   2977 C  CD1 . LEU B 2 64  ? -15.198 -4.797  3.106   1   24.89  ? 234 LEU B CD1 1 
ATOM   2978 C  CD2 . LEU B 2 64  ? -17.683 -5.035  3.361   1   26.17  ? 234 LEU B CD2 1 
ATOM   2979 N  N   . ALA B 2 65  ? -16.89  0.404   3.267   1   27.23  ? 235 ALA B N   1 
ATOM   2980 C  CA  . ALA B 2 65  ? -16.695 1.616   4.04    1   28.74  ? 235 ALA B CA  1 
ATOM   2981 C  C   . ALA B 2 65  ? -18.026 2.358   4.147   1   30.86  ? 235 ALA B C   1 
ATOM   2982 O  O   . ALA B 2 65  ? -18.418 2.819   5.23    1   31.3   ? 235 ALA B O   1 
ATOM   2983 C  CB  . ALA B 2 65  ? -15.621 2.472   3.398   1   27.5   ? 235 ALA B CB  1 
ATOM   2984 N  N   . VAL B 2 66  ? -18.717 2.436   3.008   1   25.63  ? 236 VAL B N   1 
ATOM   2985 C  CA  . VAL B 2 66  ? -19.948 3.192   2.917   1   26.76  ? 236 VAL B CA  1 
ATOM   2986 C  C   . VAL B 2 66  ? -21.015 2.498   3.763   1   27.71  ? 236 VAL B C   1 
ATOM   2987 O  O   . VAL B 2 66  ? -21.766 3.147   4.501   1   28.52  ? 236 VAL B O   1 
ATOM   2988 C  CB  . VAL B 2 66  ? -20.341 3.329   1.433   1   26.28  ? 236 VAL B CB  1 
ATOM   2989 C  CG1 . VAL B 2 66  ? -21.705 3.979   1.261   1   26.43  ? 236 VAL B CG1 1 
ATOM   2990 C  CG2 . VAL B 2 66  ? -19.29  4.103   0.654   1   22.66  ? 236 VAL B CG2 1 
ATOM   2991 N  N   . ASN B 2 67  ? -21.015 1.167   3.725   1   25.88  ? 237 ASN B N   1 
ATOM   2992 C  CA  . ASN B 2 67  ? -21.916 0.413   4.58    1   26.18  ? 237 ASN B CA  1 
ATOM   2993 C  C   . ASN B 2 67  ? -21.662 0.787   6.034   1   26.74  ? 237 ASN B C   1 
ATOM   2994 O  O   . ASN B 2 67  ? -22.636 0.933   6.766   1   30.98  ? 237 ASN B O   1 
ATOM   2995 C  CB  . ASN B 2 67  ? -21.823 -1.096  4.358   1   25.56  ? 237 ASN B CB  1 
ATOM   2996 C  CG  . ASN B 2 67  ? -22.599 -1.871  5.39    1   27.38  ? 237 ASN B CG  1 
ATOM   2997 O  OD1 . ASN B 2 67  ? -22.058 -2.241  6.434   1   34.89  ? 237 ASN B OD1 1 
ATOM   2998 N  ND2 . ASN B 2 67  ? -23.878 -2.087  5.16    1   29.49  ? 237 ASN B ND2 1 
ATOM   2999 N  N   . TYR B 2 68  ? -20.381 0.895   6.44    1   25.63  ? 238 TYR B N   1 
ATOM   3000 C  CA  . TYR B 2 68  ? -20.019 1.174   7.829   1   26.66  ? 238 TYR B CA  1 
ATOM   3001 C  C   . TYR B 2 68  ? -20.515 2.566   8.199   1   28.34  ? 238 TYR B C   1 
ATOM   3002 O  O   . TYR B 2 68  ? -21.101 2.751   9.272   1   28.51  ? 238 TYR B O   1 
ATOM   3003 C  CB  . TYR B 2 68  ? -18.535 1.044   8.177   1   25.89  ? 238 TYR B CB  1 
ATOM   3004 C  CG  . TYR B 2 68  ? -17.912 -0.313  7.863   1   24.58  ? 238 TYR B CG  1 
ATOM   3005 C  CD1 . TYR B 2 68  ? -18.692 -1.441  7.603   1   24.53  ? 238 TYR B CD1 1 
ATOM   3006 C  CD2 . TYR B 2 68  ? -16.538 -0.451  7.788   1   22.78  ? 238 TYR B CD2 1 
ATOM   3007 C  CE1 . TYR B 2 68  ? -18.128 -2.673  7.298   1   24.04  ? 238 TYR B CE1 1 
ATOM   3008 C  CE2 . TYR B 2 68  ? -15.958 -1.671  7.479   1   23.24  ? 238 TYR B CE2 1 
ATOM   3009 C  CZ  . TYR B 2 68  ? -16.75  -2.784  7.239   1   24.2   ? 238 TYR B CZ  1 
ATOM   3010 O  OH  . TYR B 2 68  ? -16.156 -3.973  6.937   1   23.48  ? 238 TYR B OH  1 
ATOM   3011 N  N   . ILE B 2 69  ? -20.329 3.507   7.258   1   28.07  ? 239 ILE B N   1 
ATOM   3012 C  CA  . ILE B 2 69  ? -20.676 4.903   7.469   1   27.6   ? 239 ILE B CA  1 
ATOM   3013 C  C   . ILE B 2 69  ? -22.188 5.031   7.664   1   27.42  ? 239 ILE B C   1 
ATOM   3014 O  O   . ILE B 2 69  ? -22.639 5.673   8.612   1   24.9   ? 239 ILE B O   1 
ATOM   3015 C  CB  . ILE B 2 69  ? -20.186 5.789   6.306   1   27.2   ? 239 ILE B CB  1 
ATOM   3016 C  CG1 . ILE B 2 69  ? -18.677 5.923   6.283   1   29.21  ? 239 ILE B CG1 1 
ATOM   3017 C  CG2 . ILE B 2 69  ? -20.855 7.167   6.344   1   22.79  ? 239 ILE B CG2 1 
ATOM   3018 C  CD1 . ILE B 2 69  ? -18.135 6.523   4.989   1   29.13  ? 239 ILE B CD1 1 
ATOM   3019 N  N   . ASP B 2 70  ? -22.954 4.461   6.726   1   27.16  ? 240 ASP B N   1 
ATOM   3020 C  CA  . ASP B 2 70  ? -24.392 4.624   6.774   1   29.44  ? 240 ASP B CA  1 
ATOM   3021 C  C   . ASP B 2 70  ? -24.945 3.967   8.033   1   29.19  ? 240 ASP B C   1 
ATOM   3022 O  O   . ASP B 2 70  ? -25.87  4.494   8.629   1   31.89  ? 240 ASP B O   1 
ATOM   3023 C  CB  . ASP B 2 70  ? -25.086 4.066   5.546   1   33.24  ? 240 ASP B CB  1 
ATOM   3024 C  CG  . ASP B 2 70  ? -24.849 4.813   4.242   1   33.01  ? 240 ASP B CG  1 
ATOM   3025 O  OD1 . ASP B 2 70  ? -24.734 6.04    4.289   1   32.19  ? 240 ASP B OD1 1 
ATOM   3026 O  OD2 . ASP B 2 70  ? -24.828 4.15    3.181   1   35.38  ? 240 ASP B OD2 1 
ATOM   3027 N  N   . ARG B 2 71  ? -24.372 2.828   8.425   1   28.63  ? 241 ARG B N   1 
ATOM   3028 C  CA  . ARG B 2 71  ? -24.855 2.115   9.637   1   29.13  ? 241 ARG B CA  1 
ATOM   3029 C  C   . ARG B 2 71  ? -24.507 2.946   10.881  1   28.04  ? 241 ARG B C   1 
ATOM   3030 O  O   . ARG B 2 71  ? -25.294 2.917   11.851  1   30.92  ? 241 ARG B O   1 
ATOM   3031 C  CB  . ARG B 2 71  ? -24.245 0.712   9.706   1   26.29  ? 241 ARG B CB  1 
ATOM   3032 C  CG  . ARG B 2 71  ? -24.992 -0.306  8.858   1   27.3   ? 241 ARG B CG  1 
ATOM   3033 C  CD  . ARG B 2 71  ? -24.263 -1.637  8.846   1   26.98  ? 241 ARG B CD  1 
ATOM   3034 N  NE  . ARG B 2 71  ? -23.586 -1.909  10.117  1   23.55  ? 241 ARG B NE  1 
ATOM   3035 C  CZ  . ARG B 2 71  ? -22.569 -2.747  10.261  1   25.73  ? 241 ARG B CZ  1 
ATOM   3036 N  NH1 . ARG B 2 71  ? -21.681 -2.885  9.292   1   21.74  ? 241 ARG B NH1 1 
ATOM   3037 N  NH2 . ARG B 2 71  ? -22.443 -3.44   11.378  1   28.78  ? 241 ARG B NH2 1 
ATOM   3038 N  N   . PHE B 2 72  ? -23.378 3.658   10.851  1   27.03  ? 242 PHE B N   1 
ATOM   3039 C  CA  . PHE B 2 72  ? -22.965 4.47    11.98   1   24.23  ? 242 PHE B CA  1 
ATOM   3040 C  C   . PHE B 2 72  ? -23.904 5.674   12.089  1   25.52  ? 242 PHE B C   1 
ATOM   3041 O  O   . PHE B 2 72  ? -24.477 5.928   13.146  1   23.61  ? 242 PHE B O   1 
ATOM   3042 C  CB  . PHE B 2 72  ? -21.47  4.765   11.852  1   22.41  ? 242 PHE B CB  1 
ATOM   3043 C  CG  . PHE B 2 72  ? -20.907 5.617   12.979  1   23.86  ? 242 PHE B CG  1 
ATOM   3044 C  CD1 . PHE B 2 72  ? -21.016 7.011   12.963  1   23.65  ? 242 PHE B CD1 1 
ATOM   3045 C  CD2 . PHE B 2 72  ? -20.271 5.02    14.069  1   23.96  ? 242 PHE B CD2 1 
ATOM   3046 C  CE1 . PHE B 2 72  ? -20.47  7.777   13.997  1   22.78  ? 242 PHE B CE1 1 
ATOM   3047 C  CE2 . PHE B 2 72  ? -19.73  5.8     15.092  1   22.66  ? 242 PHE B CE2 1 
ATOM   3048 C  CZ  . PHE B 2 72  ? -19.81  7.173   15.047  1   20.94  ? 242 PHE B CZ  1 
ATOM   3049 N  N   . LEU B 2 73  ? -24.12  6.367   10.968  1   26.83  ? 243 LEU B N   1 
ATOM   3050 C  CA  . LEU B 2 73  ? -24.927 7.575   10.972  1   27.84  ? 243 LEU B CA  1 
ATOM   3051 C  C   . LEU B 2 73  ? -26.385 7.23    11.239  1   28.07  ? 243 LEU B C   1 
ATOM   3052 O  O   . LEU B 2 73  ? -27.169 8.123   11.575  1   31.92  ? 243 LEU B O   1 
ATOM   3053 C  CB  . LEU B 2 73  ? -24.774 8.352   9.669   1   26.33  ? 243 LEU B CB  1 
ATOM   3054 C  CG  . LEU B 2 73  ? -23.361 8.864   9.389   1   26.17  ? 243 LEU B CG  1 
ATOM   3055 C  CD1 . LEU B 2 73  ? -23.239 9.377   7.956   1   24.06  ? 243 LEU B CD1 1 
ATOM   3056 C  CD2 . LEU B 2 73  ? -22.95  9.865   10.471  1   21.87  ? 243 LEU B CD2 1 
ATOM   3057 N  N   . SER B 2 74  ? -26.724 5.943   11.112  1   25.54  ? 244 SER B N   1 
ATOM   3058 C  CA  . SER B 2 74  ? -28.063 5.476   11.45   1   27.5   ? 244 SER B CA  1 
ATOM   3059 C  C   . SER B 2 74  ? -28.342 5.542   12.949  1   25.02  ? 244 SER B C   1 
ATOM   3060 O  O   . SER B 2 74  ? -29.5   5.62    13.321  1   23.94  ? 244 SER B O   1 
ATOM   3061 C  CB  . SER B 2 74  ? -28.348 4.096   10.947  1   27.8   ? 244 SER B CB  1 
ATOM   3062 O  OG  . SER B 2 74  ? -28.403 4.107   9.534   1   35.74  ? 244 SER B OG  1 
ATOM   3063 N  N   . SER B 2 75  ? -27.302 5.503   13.798  1   25.05  ? 245 SER B N   1 
ATOM   3064 C  CA  . SER B 2 75  ? -27.529 5.625   15.235  1   25.42  ? 245 SER B CA  1 
ATOM   3065 C  C   . SER B 2 75  ? -26.727 6.749   15.9    1   24.03  ? 245 SER B C   1 
ATOM   3066 O  O   . SER B 2 75  ? -27.043 7.127   17.021  1   26.08  ? 245 SER B O   1 
ATOM   3067 C  CB  . SER B 2 75  ? -27.334 4.323   15.935  1   24.75  ? 245 SER B CB  1 
ATOM   3068 O  OG  . SER B 2 75  ? -25.962 4.104   16.196  1   28.47  ? 245 SER B OG  1 
ATOM   3069 N  N   . MET B 2 76  ? -25.696 7.288   15.237  1   22.86  ? 246 MET B N   1 
ATOM   3070 C  CA  . MET B 2 76  ? -24.903 8.367   15.824  1   22.34  ? 246 MET B CA  1 
ATOM   3071 C  C   . MET B 2 76  ? -25.1   9.682   15.061  1   23.96  ? 246 MET B C   1 
ATOM   3072 O  O   . MET B 2 76  ? -24.961 9.786   13.845  1   26.29  ? 246 MET B O   1 
ATOM   3073 C  CB  . MET B 2 76  ? -23.411 8.023   15.845  1   19.91  ? 246 MET B CB  1 
ATOM   3074 C  CG  . MET B 2 76  ? -23.092 6.698   16.477  1   19.92  ? 246 MET B CG  1 
ATOM   3075 S  SD  . MET B 2 76  ? -23.367 6.648   18.254  1   23.67  ? 246 MET B SD  1 
ATOM   3076 C  CE  . MET B 2 76  ? -22.032 7.656   18.915  1   20.05  ? 246 MET B CE  1 
ATOM   3077 N  N   . SER B 2 77  ? -25.442 10.7    15.822  1   22.47  ? 247 SER B N   1 
ATOM   3078 C  CA  . SER B 2 77  ? -25.663 12.038  15.337  1   22.14  ? 247 SER B CA  1 
ATOM   3079 C  C   . SER B 2 77  ? -24.276 12.663  15.204  1   22.45  ? 247 SER B C   1 
ATOM   3080 O  O   . SER B 2 77  ? -23.467 12.546  16.124  1   21.59  ? 247 SER B O   1 
ATOM   3081 C  CB  . SER B 2 77  ? -26.482 12.742  16.41   1   21.79  ? 247 SER B CB  1 
ATOM   3082 O  OG  . SER B 2 77  ? -27.774 12.194  16.588  1   21.01  ? 247 SER B OG  1 
ATOM   3083 N  N   . VAL B 2 78  ? -23.983 13.312  14.065  1   24.13  ? 248 VAL B N   1 
ATOM   3084 C  CA  . VAL B 2 78  ? -22.62  13.777  13.814  1   24.97  ? 248 VAL B CA  1 
ATOM   3085 C  C   . VAL B 2 78  ? -22.605 15.191  13.248  1   26.07  ? 248 VAL B C   1 
ATOM   3086 O  O   . VAL B 2 78  ? -23.377 15.483  12.347  1   31.83  ? 248 VAL B O   1 
ATOM   3087 C  CB  . VAL B 2 78  ? -21.869 12.827  12.878  1   24.57  ? 248 VAL B CB  1 
ATOM   3088 C  CG1 . VAL B 2 78  ? -20.465 13.34   12.649  1   24.24  ? 248 VAL B CG1 1 
ATOM   3089 C  CG2 . VAL B 2 78  ? -21.848 11.406  13.441  1   25.19  ? 248 VAL B CG2 1 
ATOM   3090 N  N   . LEU B 2 79  ? -21.762 16.073  13.814  1   26.33  ? 249 LEU B N   1 
ATOM   3091 C  CA  . LEU B 2 79  ? -21.603 17.43   13.299  1   23.03  ? 249 LEU B CA  1 
ATOM   3092 C  C   . LEU B 2 79  ? -20.842 17.378  11.968  1   23.83  ? 249 LEU B C   1 
ATOM   3093 O  O   . LEU B 2 79  ? -20.059 16.455  11.716  1   20.4   ? 249 LEU B O   1 
ATOM   3094 C  CB  . LEU B 2 79  ? -20.92  18.343  14.318  1   20.23  ? 249 LEU B CB  1 
ATOM   3095 C  CG  . LEU B 2 79  ? -21.679 18.653  15.62   1   20.53  ? 249 LEU B CG  1 
ATOM   3096 C  CD1 . LEU B 2 79  ? -20.998 19.783  16.352  1   17.98  ? 249 LEU B CD1 1 
ATOM   3097 C  CD2 . LEU B 2 79  ? -23.163 18.97   15.481  1   19.85  ? 249 LEU B CD2 1 
ATOM   3098 N  N   . ARG B 2 80  ? -21.042 18.404  11.13   1   23.24  ? 250 ARG B N   1 
ATOM   3099 C  CA  . ARG B 2 80  ? -20.469 18.4    9.799   1   23.96  ? 250 ARG B CA  1 
ATOM   3100 C  C   . ARG B 2 80  ? -18.949 18.314  9.888   1   24.41  ? 250 ARG B C   1 
ATOM   3101 O  O   . ARG B 2 80  ? -18.345 17.628  9.057   1   22.64  ? 250 ARG B O   1 
ATOM   3102 C  CB  . ARG B 2 80  ? -20.916 19.614  8.98    1   26.15  ? 250 ARG B CB  1 
ATOM   3103 C  CG  . ARG B 2 80  ? -20.567 20.957  9.609   1   26.83  ? 250 ARG B CG  1 
ATOM   3104 C  CD  . ARG B 2 80  ? -21.181 22.084  8.796   1   25.97  ? 250 ARG B CD  1 
ATOM   3105 N  NE  . ARG B 2 80  ? -22.634 22.108  8.989   1   28.7   ? 250 ARG B NE  1 
ATOM   3106 C  CZ  . ARG B 2 80  ? -23.479 22.991  8.458   1   31.42  ? 250 ARG B CZ  1 
ATOM   3107 N  NH1 . ARG B 2 80  ? -23.071 23.863  7.543   1   32.17  ? 250 ARG B NH1 1 
ATOM   3108 N  NH2 . ARG B 2 80  ? -24.739 22.998  8.846   1   30.52  ? 250 ARG B NH2 1 
ATOM   3109 N  N   . GLY B 2 81  ? -18.361 19.033  10.87   1   23     ? 251 GLY B N   1 
ATOM   3110 C  CA  . GLY B 2 81  ? -16.923 19.066  11.094  1   21.22  ? 251 GLY B CA  1 
ATOM   3111 C  C   . GLY B 2 81  ? -16.323 17.687  11.387  1   23.21  ? 251 GLY B C   1 
ATOM   3112 O  O   . GLY B 2 81  ? -15.107 17.511  11.279  1   23.78  ? 251 GLY B O   1 
ATOM   3113 N  N   . LYS B 2 82  ? -17.175 16.722  11.779  1   22.57  ? 252 LYS B N   1 
ATOM   3114 C  CA  . LYS B 2 82  ? -16.719 15.402  12.181  1   21.73  ? 252 LYS B CA  1 
ATOM   3115 C  C   . LYS B 2 82  ? -17.085 14.326  11.16   1   21.03  ? 252 LYS B C   1 
ATOM   3116 O  O   . LYS B 2 82  ? -16.652 13.19   11.295  1   22.12  ? 252 LYS B O   1 
ATOM   3117 C  CB  . LYS B 2 82  ? -17.272 15.072  13.569  1   21.75  ? 252 LYS B CB  1 
ATOM   3118 C  CG  . LYS B 2 82  ? -16.702 15.896  14.719  1   23.27  ? 252 LYS B CG  1 
ATOM   3119 C  CD  . LYS B 2 82  ? -15.177 15.819  14.728  1   24.3   ? 252 LYS B CD  1 
ATOM   3120 C  CE  . LYS B 2 82  ? -14.504 16.133  16.023  1   22.53  ? 252 LYS B CE  1 
ATOM   3121 N  NZ  . LYS B 2 82  ? -14.663 17.571  16.238  1   22.65  ? 252 LYS B NZ  1 
ATOM   3122 N  N   . LEU B 2 83  ? -17.877 14.669  10.146  1   20.27  ? 253 LEU B N   1 
ATOM   3123 C  CA  . LEU B 2 83  ? -18.341 13.688  9.187   1   21.4   ? 253 LEU B CA  1 
ATOM   3124 C  C   . LEU B 2 83  ? -17.16  12.959  8.53    1   25.14  ? 253 LEU B C   1 
ATOM   3125 O  O   . LEU B 2 83  ? -17.227 11.759  8.297   1   25.88  ? 253 LEU B O   1 
ATOM   3126 C  CB  . LEU B 2 83  ? -19.228 14.379  8.155   1   20.06  ? 253 LEU B CB  1 
ATOM   3127 C  CG  . LEU B 2 83  ? -19.737 13.491  7.009   1   21.43  ? 253 LEU B CG  1 
ATOM   3128 C  CD1 . LEU B 2 83  ? -20.396 12.185  7.527   1   18.37  ? 253 LEU B CD1 1 
ATOM   3129 C  CD2 . LEU B 2 83  ? -20.708 14.294  6.121   1   20.21  ? 253 LEU B CD2 1 
ATOM   3130 N  N   . GLN B 2 84  ? -16.072 13.678  8.218   1   28.73  ? 254 GLN B N   1 
ATOM   3131 C  CA  . GLN B 2 84  ? -14.941 13.138  7.467   1   27.13  ? 254 GLN B CA  1 
ATOM   3132 C  C   . GLN B 2 84  ? -14.12  12.182  8.33    1   25.66  ? 254 GLN B C   1 
ATOM   3133 O  O   . GLN B 2 84  ? -13.588 11.194  7.827   1   27.22  ? 254 GLN B O   1 
ATOM   3134 C  CB  . GLN B 2 84  ? -14.061 14.249  6.885   1   27.99  ? 254 GLN B CB  1 
ATOM   3135 C  CG  . GLN B 2 84  ? -12.824 13.726  6.165   1   28.21  ? 254 GLN B CG  1 
ATOM   3136 C  CD  . GLN B 2 84  ? -12.105 14.752  5.314   1   30.47  ? 254 GLN B CD  1 
ATOM   3137 O  OE1 . GLN B 2 84  ? -11.732 14.469  4.17    1   33.27  ? 254 GLN B OE1 1 
ATOM   3138 N  NE2 . GLN B 2 84  ? -11.856 15.929  5.869   1   25.85  ? 254 GLN B NE2 1 
ATOM   3139 N  N   . LEU B 2 85  ? -14.02  12.495  9.628   1   26.14  ? 255 LEU B N   1 
ATOM   3140 C  CA  . LEU B 2 85  ? -13.401 11.624  10.619  1   24.79  ? 255 LEU B CA  1 
ATOM   3141 C  C   . LEU B 2 85  ? -14.095 10.261  10.659  1   23.37  ? 255 LEU B C   1 
ATOM   3142 O  O   . LEU B 2 85  ? -13.414 9.264   10.816  1   22.82  ? 255 LEU B O   1 
ATOM   3143 C  CB  . LEU B 2 85  ? -13.398 12.301  11.988  1   23.49  ? 255 LEU B CB  1 
ATOM   3144 C  CG  . LEU B 2 85  ? -12.766 11.496  13.131  1   23.11  ? 255 LEU B CG  1 
ATOM   3145 C  CD1 . LEU B 2 85  ? -11.351 11.033  12.778  1   21.79  ? 255 LEU B CD1 1 
ATOM   3146 C  CD2 . LEU B 2 85  ? -12.777 12.358  14.413  1   21.17  ? 255 LEU B CD2 1 
ATOM   3147 N  N   . VAL B 2 86  ? -15.433 10.229  10.531  1   23.28  ? 256 VAL B N   1 
ATOM   3148 C  CA  . VAL B 2 86  ? -16.198 8.99    10.514  1   23.72  ? 256 VAL B CA  1 
ATOM   3149 C  C   . VAL B 2 86  ? -15.849 8.238   9.239   1   24.49  ? 256 VAL B C   1 
ATOM   3150 O  O   . VAL B 2 86  ? -15.533 7.058   9.282   1   23.11  ? 256 VAL B O   1 
ATOM   3151 C  CB  . VAL B 2 86  ? -17.713 9.254   10.599  1   23.7   ? 256 VAL B CB  1 
ATOM   3152 C  CG1 . VAL B 2 86  ? -18.51  7.978   10.362  1   20.33  ? 256 VAL B CG1 1 
ATOM   3153 C  CG2 . VAL B 2 86  ? -18.106 9.956   11.901  1   21.35  ? 256 VAL B CG2 1 
ATOM   3154 N  N   . GLY B 2 87  ? -15.888 8.958   8.11    1   27.28  ? 257 GLY B N   1 
ATOM   3155 C  CA  . GLY B 2 87  ? -15.479 8.449   6.808   1   27.19  ? 257 GLY B CA  1 
ATOM   3156 C  C   . GLY B 2 87  ? -14.06  7.873   6.806   1   28.57  ? 257 GLY B C   1 
ATOM   3157 O  O   . GLY B 2 87  ? -13.847 6.776   6.267   1   24.58  ? 257 GLY B O   1 
ATOM   3158 N  N   . THR B 2 88  ? -13.101 8.603   7.42    1   26.85  ? 258 THR B N   1 
ATOM   3159 C  CA  . THR B 2 88  ? -11.714 8.154   7.491   1   25.54  ? 258 THR B CA  1 
ATOM   3160 C  C   . THR B 2 88  ? -11.6   6.84    8.259   1   27.65  ? 258 THR B C   1 
ATOM   3161 O  O   . THR B 2 88  ? -10.969 5.919   7.757   1   34.59  ? 258 THR B O   1 
ATOM   3162 C  CB  . THR B 2 88  ? -10.786 9.207   8.082   1   25.11  ? 258 THR B CB  1 
ATOM   3163 O  OG1 . THR B 2 88  ? -10.929 10.396  7.313   1   27.81  ? 258 THR B OG1 1 
ATOM   3164 C  CG2 . THR B 2 88  ? -9.328  8.787   8.026   1   25.24  ? 258 THR B CG2 1 
ATOM   3165 N  N   . ALA B 2 89  ? -12.2   6.757   9.459   1   27.42  ? 259 ALA B N   1 
ATOM   3166 C  CA  . ALA B 2 89  ? -12.154 5.573   10.319  1   24.73  ? 259 ALA B CA  1 
ATOM   3167 C  C   . ALA B 2 89  ? -12.82  4.395   9.622   1   24.98  ? 259 ALA B C   1 
ATOM   3168 O  O   . ALA B 2 89  ? -12.418 3.249   9.782   1   24.39  ? 259 ALA B O   1 
ATOM   3169 C  CB  . ALA B 2 89  ? -12.86  5.833   11.622  1   21.13  ? 259 ALA B CB  1 
ATOM   3170 N  N   . ALA B 2 90  ? -13.884 4.692   8.887   1   25.18  ? 260 ALA B N   1 
ATOM   3171 C  CA  . ALA B 2 90  ? -14.6   3.648   8.192   1   27.04  ? 260 ALA B CA  1 
ATOM   3172 C  C   . ALA B 2 90  ? -13.694 3.029   7.128   1   29.58  ? 260 ALA B C   1 
ATOM   3173 O  O   . ALA B 2 90  ? -13.565 1.805   7.078   1   30.89  ? 260 ALA B O   1 
ATOM   3174 C  CB  . ALA B 2 90  ? -15.883 4.202   7.635   1   25.29  ? 260 ALA B CB  1 
ATOM   3175 N  N   . MET B 2 91  ? -13.076 3.88    6.294   1   29.06  ? 261 MET B N   1 
ATOM   3176 C  CA  . MET B 2 91  ? -12.165 3.46    5.237   1   27.28  ? 261 MET B CA  1 
ATOM   3177 C  C   . MET B 2 91  ? -10.986 2.69    5.833   1   26.4   ? 261 MET B C   1 
ATOM   3178 O  O   . MET B 2 91  ? -10.554 1.702   5.25    1   30.14  ? 261 MET B O   1 
ATOM   3179 C  CB  . MET B 2 91  ? -11.655 4.674   4.443   1   28.98  ? 261 MET B CB  1 
ATOM   3180 C  CG  . MET B 2 91  ? -11.082 4.364   3.082   1   30.63  ? 261 MET B CG  1 
ATOM   3181 S  SD  . MET B 2 91  ? -12.369 3.646   2.044   1   37.6   ? 261 MET B SD  1 
ATOM   3182 C  CE  . MET B 2 91  ? -11.748 3.803   0.368   1   40.22  ? 261 MET B CE  1 
ATOM   3183 N  N   . LEU B 2 92  ? -10.507 3.101   7.014   1   24     ? 262 LEU B N   1 
ATOM   3184 C  CA  . LEU B 2 92  ? -9.437  2.385   7.693   1   23.55  ? 262 LEU B CA  1 
ATOM   3185 C  C   . LEU B 2 92  ? -9.888  0.974   8.096   1   25.41  ? 262 LEU B C   1 
ATOM   3186 O  O   . LEU B 2 92  ? -9.134  0.019   7.915   1   32.09  ? 262 LEU B O   1 
ATOM   3187 C  CB  . LEU B 2 92  ? -8.931  3.218   8.873   1   21.65  ? 262 LEU B CB  1 
ATOM   3188 C  CG  . LEU B 2 92  ? -7.904  2.561   9.81    1   21.39  ? 262 LEU B CG  1 
ATOM   3189 C  CD1 . LEU B 2 92  ? -6.565  2.302   9.16    1   20.24  ? 262 LEU B CD1 1 
ATOM   3190 C  CD2 . LEU B 2 92  ? -7.705  3.422   11.049  1   20.75  ? 262 LEU B CD2 1 
ATOM   3191 N  N   . LEU B 2 93  ? -11.113 0.829   8.618   1   24.31  ? 263 LEU B N   1 
ATOM   3192 C  CA  . LEU B 2 93  ? -11.635 -0.464  9.04    1   25.47  ? 263 LEU B CA  1 
ATOM   3193 C  C   . LEU B 2 93  ? -11.868 -1.34   7.811   1   25.99  ? 263 LEU B C   1 
ATOM   3194 O  O   . LEU B 2 93  ? -11.547 -2.528  7.818   1   26.19  ? 263 LEU B O   1 
ATOM   3195 C  CB  . LEU B 2 93  ? -12.91  -0.309  9.871   1   24.21  ? 263 LEU B CB  1 
ATOM   3196 C  CG  . LEU B 2 93  ? -12.711 0.206   11.298  1   25.01  ? 263 LEU B CG  1 
ATOM   3197 C  CD1 . LEU B 2 93  ? -14.024 0.581   11.949  1   25.35  ? 263 LEU B CD1 1 
ATOM   3198 C  CD2 . LEU B 2 93  ? -12.014 -0.858  12.114  1   24.7   ? 263 LEU B CD2 1 
ATOM   3199 N  N   . ALA B 2 94  ? -12.401 -0.738  6.746   1   24.3   ? 264 ALA B N   1 
ATOM   3200 C  CA  . ALA B 2 94  ? -12.693 -1.493  5.54    1   25.13  ? 264 ALA B CA  1 
ATOM   3201 C  C   . ALA B 2 94  ? -11.39  -1.984  4.914   1   27.73  ? 264 ALA B C   1 
ATOM   3202 O  O   . ALA B 2 94  ? -11.332 -3.093  4.404   1   29.69  ? 264 ALA B O   1 
ATOM   3203 C  CB  . ALA B 2 94  ? -13.486 -0.661  4.581   1   23.73  ? 264 ALA B CB  1 
ATOM   3204 N  N   . SER B 2 95  ? -10.333 -1.168  5.003   1   28.69  ? 265 SER B N   1 
ATOM   3205 C  CA  . SER B 2 95  ? -9.017  -1.542  4.513   1   25.85  ? 265 SER B CA  1 
ATOM   3206 C  C   . SER B 2 95  ? -8.436  -2.688  5.326   1   25.16  ? 265 SER B C   1 
ATOM   3207 O  O   . SER B 2 95  ? -7.898  -3.62   4.757   1   27.52  ? 265 SER B O   1 
ATOM   3208 C  CB  . SER B 2 95  ? -8.094  -0.377  4.531   1   25.86  ? 265 SER B CB  1 
ATOM   3209 O  OG  . SER B 2 95  ? -8.591  0.619   3.653   1   27.26  ? 265 SER B OG  1 
ATOM   3210 N  N   . LYS B 2 96  ? -8.516  -2.617  6.655   1   26.68  ? 266 LYS B N   1 
ATOM   3211 C  CA  . LYS B 2 96  ? -7.924  -3.672  7.474   1   24.51  ? 266 LYS B CA  1 
ATOM   3212 C  C   . LYS B 2 96  ? -8.629  -4.993  7.201   1   23.55  ? 266 LYS B C   1 
ATOM   3213 O  O   . LYS B 2 96  ? -7.988  -6.028  7.157   1   25.52  ? 266 LYS B O   1 
ATOM   3214 C  CB  . LYS B 2 96  ? -7.934  -3.301  8.957   1   22.26  ? 266 LYS B CB  1 
ATOM   3215 C  CG  . LYS B 2 96  ? -6.974  -2.197  9.361   1   19.65  ? 266 LYS B CG  1 
ATOM   3216 C  CD  . LYS B 2 96  ? -7.241  -1.729  10.785  1   19.46  ? 266 LYS B CD  1 
ATOM   3217 C  CE  . LYS B 2 96  ? -6.123  -0.906  11.344  1   19.64  ? 266 LYS B CE  1 
ATOM   3218 N  NZ  . LYS B 2 96  ? -6.264  -0.628  12.779  1   18.3   ? 266 LYS B NZ  1 
ATOM   3219 N  N   . PHE B 2 97  ? -9.935  -4.947  6.932   1   24.56  ? 267 PHE B N   1 
ATOM   3220 C  CA  . PHE B 2 97  ? -10.719 -6.159  6.767   1   25.11  ? 267 PHE B CA  1 
ATOM   3221 C  C   . PHE B 2 97  ? -10.527 -6.746  5.373   1   25.13  ? 267 PHE B C   1 
ATOM   3222 O  O   . PHE B 2 97  ? -10.469 -7.966  5.207   1   24.09  ? 267 PHE B O   1 
ATOM   3223 C  CB  . PHE B 2 97  ? -12.202 -5.828  6.957   1   26.35  ? 267 PHE B CB  1 
ATOM   3224 C  CG  . PHE B 2 97  ? -13.158 -6.995  6.772   1   26.71  ? 267 PHE B CG  1 
ATOM   3225 C  CD1 . PHE B 2 97  ? -13.654 -7.3    5.512   1   26.82  ? 267 PHE B CD1 1 
ATOM   3226 C  CD2 . PHE B 2 97  ? -13.55  -7.784  7.852   1   26.49  ? 267 PHE B CD2 1 
ATOM   3227 C  CE1 . PHE B 2 97  ? -14.53  -8.369  5.341   1   30.12  ? 267 PHE B CE1 1 
ATOM   3228 C  CE2 . PHE B 2 97  ? -14.424 -8.849  7.673   1   29.59  ? 267 PHE B CE2 1 
ATOM   3229 C  CZ  . PHE B 2 97  ? -14.92  -9.145  6.418   1   30.15  ? 267 PHE B CZ  1 
ATOM   3230 N  N   . GLU B 2 98  ? -10.443 -5.874  4.366   1   24.21  ? 268 GLU B N   1 
ATOM   3231 C  CA  . GLU B 2 98  ? -10.588 -6.365  3.008   1   25.66  ? 268 GLU B CA  1 
ATOM   3232 C  C   . GLU B 2 98  ? -9.26   -6.388  2.254   1   27.23  ? 268 GLU B C   1 
ATOM   3233 O  O   . GLU B 2 98  ? -9.081  -7.248  1.379   1   28.3   ? 268 GLU B O   1 
ATOM   3234 C  CB  . GLU B 2 98  ? -11.686 -5.58   2.305   1   23.49  ? 268 GLU B CB  1 
ATOM   3235 C  CG  . GLU B 2 98  ? -12.085 -6.203  0.983   1   24.83  ? 268 GLU B CG  1 
ATOM   3236 C  CD  . GLU B 2 98  ? -12.622 -7.609  1.112   1   28.33  ? 268 GLU B CD  1 
ATOM   3237 O  OE1 . GLU B 2 98  ? -13.354 -7.885  2.099   1   29.42  ? 268 GLU B OE1 1 
ATOM   3238 O  OE2 . GLU B 2 98  ? -12.402 -8.392  0.156   1   27.99  ? 268 GLU B OE2 1 
ATOM   3239 N  N   . GLU B 2 99  ? -8.334  -5.48   2.615   1   25.33  ? 269 GLU B N   1 
ATOM   3240 C  CA  . GLU B 2 99  ? -7.127  -5.283  1.827   1   24.87  ? 269 GLU B CA  1 
ATOM   3241 C  C   . GLU B 2 99  ? -6.036  -6.249  2.263   1   28.25  ? 269 GLU B C   1 
ATOM   3242 O  O   . GLU B 2 99  ? -5.851  -6.479  3.461   1   29.19  ? 269 GLU B O   1 
ATOM   3243 C  CB  . GLU B 2 99  ? -6.503  -3.899  1.963   1   22.87  ? 269 GLU B CB  1 
ATOM   3244 C  CG  . GLU B 2 99  ? -7.313  -2.81   1.27    1   25.76  ? 269 GLU B CG  1 
ATOM   3245 C  CD  . GLU B 2 99  ? -7.458  -2.94   -0.232  1   27.2   ? 269 GLU B CD  1 
ATOM   3246 O  OE1 . GLU B 2 99  ? -6.465  -3.304  -0.903  1   28.96  ? 269 GLU B OE1 1 
ATOM   3247 O  OE2 . GLU B 2 99  ? -8.565  -2.65   -0.722  1   28.29  ? 269 GLU B OE2 1 
ATOM   3248 N  N   . ILE B 2 100 ? -5.304  -6.764  1.258   1   26.84  ? 270 ILE B N   1 
ATOM   3249 C  CA  . ILE B 2 100 ? -4.072  -7.484  1.499   1   24.8   ? 270 ILE B CA  1 
ATOM   3250 C  C   . ILE B 2 100 ? -3.089  -6.538  2.165   1   25.43  ? 270 ILE B C   1 
ATOM   3251 O  O   . ILE B 2 100 ? -2.508  -6.912  3.173   1   27.41  ? 270 ILE B O   1 
ATOM   3252 C  CB  . ILE B 2 100 ? -3.463  -8.08   0.219   1   23.06  ? 270 ILE B CB  1 
ATOM   3253 C  CG1 . ILE B 2 100 ? -4.434  -9      -0.545  1   21.21  ? 270 ILE B CG1 1 
ATOM   3254 C  CG2 . ILE B 2 100 ? -2.166  -8.794  0.573   1   19.66  ? 270 ILE B CG2 1 
ATOM   3255 C  CD1 . ILE B 2 100 ? -3.844  -9.617  -1.803  1   18.14  ? 270 ILE B CD1 1 
ATOM   3256 N  N   . TYR B 2 101 ? -2.851  -5.369  1.549   1   26.41  ? 271 TYR B N   1 
ATOM   3257 C  CA  . TYR B 2 101 ? -1.93   -4.373  2.098   1   27.81  ? 271 TYR B CA  1 
ATOM   3258 C  C   . TYR B 2 101 ? -2.664  -3.074  2.433   1   28.86  ? 271 TYR B C   1 
ATOM   3259 O  O   . TYR B 2 101 ? -2.715  -2.146  1.619   1   30.78  ? 271 TYR B O   1 
ATOM   3260 C  CB  . TYR B 2 101 ? -0.752  -4.087  1.163   1   27.15  ? 271 TYR B CB  1 
ATOM   3261 C  CG  . TYR B 2 101 ? 0.125   -5.301  0.923   1   29.47  ? 271 TYR B CG  1 
ATOM   3262 C  CD1 . TYR B 2 101 ? 0.872   -5.848  1.968   1   29.18  ? 271 TYR B CD1 1 
ATOM   3263 C  CD2 . TYR B 2 101 ? 0.186   -5.899  -0.34   1   30.17  ? 271 TYR B CD2 1 
ATOM   3264 C  CE1 . TYR B 2 101 ? 1.673   -6.96   1.762   1   31.44  ? 271 TYR B CE1 1 
ATOM   3265 C  CE2 . TYR B 2 101 ? 0.973   -7.017  -0.553  1   32.79  ? 271 TYR B CE2 1 
ATOM   3266 C  CZ  . TYR B 2 101 ? 1.715   -7.539  0.498   1   36.4   ? 271 TYR B CZ  1 
ATOM   3267 O  OH  . TYR B 2 101 ? 2.474   -8.641  0.235   1   46.71  ? 271 TYR B OH  1 
ATOM   3268 N  N   . PRO B 2 102 ? -3.293  -2.966  3.626   1   28.61  ? 272 PRO B N   1 
ATOM   3269 C  CA  . PRO B 2 102 ? -4.009  -1.737  3.987   1   26.14  ? 272 PRO B CA  1 
ATOM   3270 C  C   . PRO B 2 102 ? -3.013  -0.588  4.106   1   25.68  ? 272 PRO B C   1 
ATOM   3271 O  O   . PRO B 2 102 ? -1.854  -0.784  4.485   1   25.25  ? 272 PRO B O   1 
ATOM   3272 C  CB  . PRO B 2 102 ? -4.667  -2.043  5.332   1   25.18  ? 272 PRO B CB  1 
ATOM   3273 C  CG  . PRO B 2 102 ? -3.882  -3.239  5.864   1   26.94  ? 272 PRO B CG  1 
ATOM   3274 C  CD  . PRO B 2 102 ? -3.359  -4.012  4.664   1   26.65  ? 272 PRO B CD  1 
ATOM   3275 N  N   . PRO B 2 103 ? -3.427  0.654   3.79    1   24.3   ? 273 PRO B N   1 
ATOM   3276 C  CA  . PRO B 2 103 ? -2.59   1.811   4.109   1   25     ? 273 PRO B CA  1 
ATOM   3277 C  C   . PRO B 2 103 ? -2.427  1.923   5.621   1   25.53  ? 273 PRO B C   1 
ATOM   3278 O  O   . PRO B 2 103 ? -3.32   1.591   6.388   1   23.5   ? 273 PRO B O   1 
ATOM   3279 C  CB  . PRO B 2 103 ? -3.347  2.996   3.508   1   23.2   ? 273 PRO B CB  1 
ATOM   3280 C  CG  . PRO B 2 103 ? -4.298  2.354   2.507   1   22.64  ? 273 PRO B CG  1 
ATOM   3281 C  CD  . PRO B 2 103 ? -4.674  1.001   3.094   1   22.41  ? 273 PRO B CD  1 
ATOM   3282 N  N   . GLU B 2 104 ? -1.245  2.371   6.034   1   30.36  ? 274 GLU B N   1 
ATOM   3283 C  CA  . GLU B 2 104 ? -0.952  2.678   7.425   1   35.48  ? 274 GLU B CA  1 
ATOM   3284 C  C   . GLU B 2 104 ? -1.875  3.792   7.93    1   33.57  ? 274 GLU B C   1 
ATOM   3285 O  O   . GLU B 2 104 ? -2.283  4.674   7.175   1   34.46  ? 274 GLU B O   1 
ATOM   3286 C  CB  . GLU B 2 104 ? 0.499   3.156   7.52    1   39.88  ? 274 GLU B CB  1 
ATOM   3287 C  CG  . GLU B 2 104 ? 1.515   2.17    6.953   1   49.63  ? 274 GLU B CG  1 
ATOM   3288 C  CD  . GLU B 2 104 ? 2.879   2.228   7.607   1   66.47  ? 274 GLU B CD  1 
ATOM   3289 O  OE1 . GLU B 2 104 ? 3.439   1.149   7.923   1   68.89  ? 274 GLU B OE1 1 
ATOM   3290 O  OE2 . GLU B 2 104 ? 3.368   3.361   7.821   1   78.48  ? 274 GLU B OE2 1 
ATOM   3291 N  N   . VAL B 2 105 ? -2.184  3.756   9.228   1   32.29  ? 275 VAL B N   1 
ATOM   3292 C  CA  . VAL B 2 105 ? -3.014  4.764   9.877   1   32.73  ? 275 VAL B CA  1 
ATOM   3293 C  C   . VAL B 2 105 ? -2.576  6.177   9.479   1   32.48  ? 275 VAL B C   1 
ATOM   3294 O  O   . VAL B 2 105 ? -3.434  7.02    9.226   1   36.86  ? 275 VAL B O   1 
ATOM   3295 C  CB  . VAL B 2 105 ? -2.998  4.587   11.407  1   31.11  ? 275 VAL B CB  1 
ATOM   3296 C  CG1 . VAL B 2 105 ? -3.608  5.771   12.133  1   28.8   ? 275 VAL B CG1 1 
ATOM   3297 C  CG2 . VAL B 2 105 ? -3.676  3.291   11.825  1   31.32  ? 275 VAL B CG2 1 
ATOM   3298 N  N   . ALA B 2 106 ? -1.258  6.424   9.401   1   28.43  ? 276 ALA B N   1 
ATOM   3299 C  CA  . ALA B 2 106 ? -0.733  7.752   9.112   1   28.45  ? 276 ALA B CA  1 
ATOM   3300 C  C   . ALA B 2 106 ? -1.059  8.196   7.682   1   29.73  ? 276 ALA B C   1 
ATOM   3301 O  O   . ALA B 2 106 ? -0.996  9.379   7.371   1   33.32  ? 276 ALA B O   1 
ATOM   3302 C  CB  . ALA B 2 106 ? 0.755   7.833   9.381   1   22.2   ? 276 ALA B CB  1 
ATOM   3303 N  N   . GLU B 2 107 ? -1.349  7.252   6.791   1   28.86  ? 277 GLU B N   1 
ATOM   3304 C  CA  . GLU B 2 107 ? -1.723  7.652   5.45    1   31.27  ? 277 GLU B CA  1 
ATOM   3305 C  C   . GLU B 2 107 ? -3.162  8.155   5.483   1   30.9   ? 277 GLU B C   1 
ATOM   3306 O  O   . GLU B 2 107 ? -3.509  9.111   4.793   1   31.04  ? 277 GLU B O   1 
ATOM   3307 C  CB  . GLU B 2 107 ? -1.466  6.536   4.438   1   35.9   ? 277 GLU B CB  1 
ATOM   3308 C  CG  . GLU B 2 107 ? 0.003   6.404   4.047   1   42.11  ? 277 GLU B CG  1 
ATOM   3309 C  CD  . GLU B 2 107 ? 0.329   5.176   3.217   1   53.87  ? 277 GLU B CD  1 
ATOM   3310 O  OE1 . GLU B 2 107 ? 0.921   5.374   2.14    1   65.51  ? 277 GLU B OE1 1 
ATOM   3311 O  OE2 . GLU B 2 107 ? 0.02    4.03    3.624   1   59.38  ? 277 GLU B OE2 1 
ATOM   3312 N  N   . PHE B 2 108 ? -4.004  7.497   6.286   1   29.18  ? 278 PHE B N   1 
ATOM   3313 C  CA  . PHE B 2 108 ? -5.343  8.017   6.502   1   30.38  ? 278 PHE B CA  1 
ATOM   3314 C  C   . PHE B 2 108 ? -5.283  9.423   7.113   1   34.39  ? 278 PHE B C   1 
ATOM   3315 O  O   . PHE B 2 108 ? -6.033  10.302  6.695   1   40.31  ? 278 PHE B O   1 
ATOM   3316 C  CB  . PHE B 2 108 ? -6.191  7.015   7.278   1   28.6   ? 278 PHE B CB  1 
ATOM   3317 C  CG  . PHE B 2 108 ? -6.492  5.803   6.423   1   31.03  ? 278 PHE B CG  1 
ATOM   3318 C  CD1 . PHE B 2 108 ? -7.492  5.852   5.461   1   30.06  ? 278 PHE B CD1 1 
ATOM   3319 C  CD2 . PHE B 2 108 ? -5.755  4.627   6.565   1   30.94  ? 278 PHE B CD2 1 
ATOM   3320 C  CE1 . PHE B 2 108 ? -7.735  4.744   4.658   1   32.79  ? 278 PHE B CE1 1 
ATOM   3321 C  CE2 . PHE B 2 108 ? -6.017  3.522   5.761   1   28.97  ? 278 PHE B CE2 1 
ATOM   3322 C  CZ  . PHE B 2 108 ? -7.004  3.579   4.805   1   28.72  ? 278 PHE B CZ  1 
ATOM   3323 N  N   . VAL B 2 109 ? -4.398  9.655   8.092   1   30.52  ? 279 VAL B N   1 
ATOM   3324 C  CA  . VAL B 2 109 ? -4.312  10.976  8.682   1   29.92  ? 279 VAL B CA  1 
ATOM   3325 C  C   . VAL B 2 109 ? -3.907  11.976  7.598   1   32.42  ? 279 VAL B C   1 
ATOM   3326 O  O   . VAL B 2 109 ? -4.413  13.093  7.576   1   37.81  ? 279 VAL B O   1 
ATOM   3327 C  CB  . VAL B 2 109 ? -3.343  10.998  9.879   1   28.83  ? 279 VAL B CB  1 
ATOM   3328 C  CG1 . VAL B 2 109 ? -3.227  12.383  10.497  1   24.79  ? 279 VAL B CG1 1 
ATOM   3329 C  CG2 . VAL B 2 109 ? -3.707  9.971   10.944  1   28.12  ? 279 VAL B CG2 1 
ATOM   3330 N  N   . TYR B 2 110 ? -3.004  11.569  6.698   1   34.66  ? 280 TYR B N   1 
ATOM   3331 C  CA  . TYR B 2 110 ? -2.449  12.429  5.664   1   35.22  ? 280 TYR B CA  1 
ATOM   3332 C  C   . TYR B 2 110 ? -3.527  12.894  4.68    1   37.32  ? 280 TYR B C   1 
ATOM   3333 O  O   . TYR B 2 110 ? -3.552  14.066  4.318   1   43.07  ? 280 TYR B O   1 
ATOM   3334 C  CB  . TYR B 2 110 ? -1.222  11.823  4.974   1   39.37  ? 280 TYR B CB  1 
ATOM   3335 C  CG  . TYR B 2 110 ? -0.687  12.643  3.8     1   51.28  ? 280 TYR B CG  1 
ATOM   3336 C  CD1 . TYR B 2 110 ? -0.119  13.906  4.002   1   52.24  ? 280 TYR B CD1 1 
ATOM   3337 C  CD2 . TYR B 2 110 ? -0.732  12.154  2.489   1   52.88  ? 280 TYR B CD2 1 
ATOM   3338 C  CE1 . TYR B 2 110 ? 0.36    14.66   2.939   1   53.9   ? 280 TYR B CE1 1 
ATOM   3339 C  CE2 . TYR B 2 110 ? -0.25   12.897  1.42    1   53.9   ? 280 TYR B CE2 1 
ATOM   3340 C  CZ  . TYR B 2 110 ? 0.299   14.152  1.648   1   58.99  ? 280 TYR B CZ  1 
ATOM   3341 O  OH  . TYR B 2 110 ? 0.781   14.897  0.605   1   63.75  ? 280 TYR B OH  1 
ATOM   3342 N  N   . ILE B 2 111 ? -4.435  12.006  4.262   1   37.01  ? 281 ILE B N   1 
ATOM   3343 C  CA  . ILE B 2 111 ? -5.397  12.361  3.226   1   38.72  ? 281 ILE B CA  1 
ATOM   3344 C  C   . ILE B 2 111 ? -6.515  13.252  3.754   1   39.41  ? 281 ILE B C   1 
ATOM   3345 O  O   . ILE B 2 111 ? -7.299  13.746  2.952   1   45.63  ? 281 ILE B O   1 
ATOM   3346 C  CB  . ILE B 2 111 ? -6.031  11.128  2.572   1   40.78  ? 281 ILE B CB  1 
ATOM   3347 C  CG1 . ILE B 2 111 ? -6.633  10.224  3.637   1   41.23  ? 281 ILE B CG1 1 
ATOM   3348 C  CG2 . ILE B 2 111 ? -5.027  10.42   1.671   1   40.54  ? 281 ILE B CG2 1 
ATOM   3349 C  CD1 . ILE B 2 111 ? -7.949  9.572   3.244   1   52.75  ? 281 ILE B CD1 1 
ATOM   3350 N  N   . THR B 2 112 ? -6.661  13.372  5.076   1   40.44  ? 282 THR B N   1 
ATOM   3351 C  CA  . THR B 2 112 ? -7.636  14.297  5.643   1   41.72  ? 282 THR B CA  1 
ATOM   3352 C  C   . THR B 2 112 ? -7.026  15.688  5.782   1   46.09  ? 282 THR B C   1 
ATOM   3353 O  O   . THR B 2 112 ? -7.625  16.533  6.452   1   46.47  ? 282 THR B O   1 
ATOM   3354 C  CB  . THR B 2 112 ? -8.171  13.841  7.003   1   39.84  ? 282 THR B CB  1 
ATOM   3355 O  OG1 . THR B 2 112 ? -7.06   13.786  7.891   1   43.42  ? 282 THR B OG1 1 
ATOM   3356 C  CG2 . THR B 2 112 ? -8.919  12.524  6.986   1   30.28  ? 282 THR B CG2 1 
ATOM   3357 N  N   . ASP B 2 113 ? -5.823  15.884  5.209   1   56.98  ? 283 ASP B N   1 
ATOM   3358 C  CA  . ASP B 2 113 ? -5.114  17.163  5.135   1   66.53  ? 283 ASP B CA  1 
ATOM   3359 C  C   . ASP B 2 113 ? -4.771  17.692  6.529   1   63.2   ? 283 ASP B C   1 
ATOM   3360 O  O   . ASP B 2 113 ? -4.727  18.901  6.729   1   58.76  ? 283 ASP B O   1 
ATOM   3361 C  CB  . ASP B 2 113 ? -5.861  18.206  4.304   1   77.18  ? 283 ASP B CB  1 
ATOM   3362 C  CG  . ASP B 2 113 ? -5.804  18.056  2.785   1   87.54  ? 283 ASP B CG  1 
ATOM   3363 O  OD1 . ASP B 2 113 ? -5.232  17.05   2.317   1   85.06  ? 283 ASP B OD1 1 
ATOM   3364 O  OD2 . ASP B 2 113 ? -6.329  18.952  2.076   1   90.24  ? 283 ASP B OD2 1 
ATOM   3365 N  N   . ASP B 2 114 ? -4.554  16.779  7.487   1   69.99  ? 284 ASP B N   1 
ATOM   3366 C  CA  . ASP B 2 114 ? -4.369  17.118  8.895   1   69.15  ? 284 ASP B CA  1 
ATOM   3367 C  C   . ASP B 2 114 ? -5.505  17.983  9.441   1   53.84  ? 284 ASP B C   1 
ATOM   3368 O  O   . ASP B 2 114 ? -5.278  18.884  10.245  1   42.34  ? 284 ASP B O   1 
ATOM   3369 C  CB  . ASP B 2 114 ? -2.985  17.686  9.16    1   86.61  ? 284 ASP B CB  1 
ATOM   3370 C  CG  . ASP B 2 114 ? -1.881  16.65   9.06    1   98.13  ? 284 ASP B CG  1 
ATOM   3371 O  OD1 . ASP B 2 114 ? -1.799  15.802  9.982   1   96.22  ? 284 ASP B OD1 1 
ATOM   3372 O  OD2 . ASP B 2 114 ? -1.163  16.67   8.036   1   96.73  ? 284 ASP B OD2 1 
ATOM   3373 N  N   . THR B 2 115 ? -6.734  17.694  9.004   1   49.15  ? 285 THR B N   1 
ATOM   3374 C  CA  . THR B 2 115 ? -7.9    18.12   9.757   1   49.73  ? 285 THR B CA  1 
ATOM   3375 C  C   . THR B 2 115 ? -7.813  17.465  11.145  1   42.67  ? 285 THR B C   1 
ATOM   3376 O  O   . THR B 2 115 ? -7.919  18.14   12.166  1   49.19  ? 285 THR B O   1 
ATOM   3377 C  CB  . THR B 2 115 ? -9.189  17.783  8.987   1   54.1   ? 285 THR B CB  1 
ATOM   3378 O  OG1 . THR B 2 115 ? -9.05   18.051  7.594   1   47.74  ? 285 THR B OG1 1 
ATOM   3379 C  CG2 . THR B 2 115 ? -10.398 18.558  9.485   1   49.69  ? 285 THR B CG2 1 
ATOM   3380 N  N   . TYR B 2 116 ? -7.528  16.158  11.172  1   33.75  ? 286 TYR B N   1 
ATOM   3381 C  CA  . TYR B 2 116 ? -7.6    15.349  12.38   1   31.69  ? 286 TYR B CA  1 
ATOM   3382 C  C   . TYR B 2 116 ? -6.23   14.8    12.763  1   31.53  ? 286 TYR B C   1 
ATOM   3383 O  O   . TYR B 2 116 ? -5.293  14.872  11.976  1   35.64  ? 286 TYR B O   1 
ATOM   3384 C  CB  . TYR B 2 116 ? -8.546  14.163  12.177  1   28.67  ? 286 TYR B CB  1 
ATOM   3385 C  CG  . TYR B 2 116 ? -9.898  14.599  11.635  1   28.41  ? 286 TYR B CG  1 
ATOM   3386 C  CD1 . TYR B 2 116 ? -10.77  15.378  12.395  1   27.62  ? 286 TYR B CD1 1 
ATOM   3387 C  CD2 . TYR B 2 116 ? -10.262 14.294  10.335  1   26.49  ? 286 TYR B CD2 1 
ATOM   3388 C  CE1 . TYR B 2 116 ? -11.982 15.813  11.881  1   25.43  ? 286 TYR B CE1 1 
ATOM   3389 C  CE2 . TYR B 2 116 ? -11.468 14.728  9.817   1   26.57  ? 286 TYR B CE2 1 
ATOM   3390 C  CZ  . TYR B 2 116 ? -12.334 15.476  10.588  1   24.31  ? 286 TYR B CZ  1 
ATOM   3391 O  OH  . TYR B 2 116 ? -13.523 15.825  10.012  1   24.45  ? 286 TYR B OH  1 
ATOM   3392 N  N   . THR B 2 117 ? -6.137  14.276  13.997  1   29.53  ? 287 THR B N   1 
ATOM   3393 C  CA  . THR B 2 117 ? -4.921  13.681  14.529  1   29     ? 287 THR B CA  1 
ATOM   3394 C  C   . THR B 2 117 ? -4.994  12.161  14.415  1   31.53  ? 287 THR B C   1 
ATOM   3395 O  O   . THR B 2 117 ? -6.051  11.582  14.186  1   30.48  ? 287 THR B O   1 
ATOM   3396 C  CB  . THR B 2 117 ? -4.675  14.092  15.982  1   30.01  ? 287 THR B CB  1 
ATOM   3397 O  OG1 . THR B 2 117 ? -5.731  13.579  16.79   1   32.65  ? 287 THR B OG1 1 
ATOM   3398 C  CG2 . THR B 2 117 ? -4.526  15.592  16.168  1   25.39  ? 287 THR B CG2 1 
ATOM   3399 N  N   . LYS B 2 118 ? -3.837  11.519  14.576  1   33.56  ? 288 LYS B N   1 
ATOM   3400 C  CA  . LYS B 2 118 ? -3.752  10.073  14.546  1   33.58  ? 288 LYS B CA  1 
ATOM   3401 C  C   . LYS B 2 118 ? -4.625  9.551   15.681  1   31.78  ? 288 LYS B C   1 
ATOM   3402 O  O   . LYS B 2 118 ? -5.346  8.576   15.514  1   34.61  ? 288 LYS B O   1 
ATOM   3403 C  CB  . LYS B 2 118 ? -2.28   9.656   14.656  1   35.89  ? 288 LYS B CB  1 
ATOM   3404 C  CG  . LYS B 2 118 ? -1.949  8.193   14.392  1   40.46  ? 288 LYS B CG  1 
ATOM   3405 C  CD  . LYS B 2 118 ? -0.629  7.737   15.016  1   45.05  ? 288 LYS B CD  1 
ATOM   3406 C  CE  . LYS B 2 118 ? -0.484  6.239   15.088  1   51.51  ? 288 LYS B CE  1 
ATOM   3407 N  NZ  . LYS B 2 118 ? 0.25    5.754   16.263  1   51.95  ? 288 LYS B NZ  1 
ATOM   3408 N  N   . LYS B 2 119 ? -4.599  10.254  16.81   1   31.01  ? 289 LYS B N   1 
ATOM   3409 C  CA  . LYS B 2 119 ? -5.34   9.861   17.997  1   31.47  ? 289 LYS B CA  1 
ATOM   3410 C  C   . LYS B 2 119 ? -6.835  9.909   17.706  1   29.12  ? 289 LYS B C   1 
ATOM   3411 O  O   . LYS B 2 119 ? -7.575  9.008   18.074  1   28.5   ? 289 LYS B O   1 
ATOM   3412 C  CB  . LYS B 2 119 ? -4.978  10.8    19.153  1   34.29  ? 289 LYS B CB  1 
ATOM   3413 C  CG  . LYS B 2 119 ? -5.398  10.297  20.519  1   43.07  ? 289 LYS B CG  1 
ATOM   3414 C  CD  . LYS B 2 119 ? -4.729  11.007  21.693  1   55.28  ? 289 LYS B CD  1 
ATOM   3415 C  CE  . LYS B 2 119 ? -5.435  12.208  22.275  1   56.47  ? 289 LYS B CE  1 
ATOM   3416 N  NZ  . LYS B 2 119 ? -6.671  11.772  22.935  1   53.45  ? 289 LYS B NZ  1 
ATOM   3417 N  N   . GLN B 2 120 ? -7.273  10.967  17.029  1   27.87  ? 290 GLN B N   1 
ATOM   3418 C  CA  . GLN B 2 120 ? -8.677  11.093  16.677  1   28.44  ? 290 GLN B CA  1 
ATOM   3419 C  C   . GLN B 2 120 ? -9.119  9.966   15.733  1   25.79  ? 290 GLN B C   1 
ATOM   3420 O  O   . GLN B 2 120 ? -10.211 9.416   15.873  1   24.64  ? 290 GLN B O   1 
ATOM   3421 C  CB  . GLN B 2 120 ? -8.952  12.458  16.049  1   28.56  ? 290 GLN B CB  1 
ATOM   3422 C  CG  . GLN B 2 120 ? -8.936  13.639  17.014  1   31.64  ? 290 GLN B CG  1 
ATOM   3423 C  CD  . GLN B 2 120 ? -9.225  14.946  16.299  1   34.01  ? 290 GLN B CD  1 
ATOM   3424 O  OE1 . GLN B 2 120 ? -8.512  15.349  15.367  1   34.78  ? 290 GLN B OE1 1 
ATOM   3425 N  NE2 . GLN B 2 120 ? -10.328 15.581  16.675  1   30.45  ? 290 GLN B NE2 1 
ATOM   3426 N  N   . VAL B 2 121 ? -8.309  9.669   14.719  1   25.15  ? 291 VAL B N   1 
ATOM   3427 C  CA  . VAL B 2 121 ? -8.639  8.597   13.797  1   24.79  ? 291 VAL B CA  1 
ATOM   3428 C  C   . VAL B 2 121 ? -8.746  7.28    14.569  1   24.97  ? 291 VAL B C   1 
ATOM   3429 O  O   . VAL B 2 121 ? -9.7    6.524   14.391  1   22.94  ? 291 VAL B O   1 
ATOM   3430 C  CB  . VAL B 2 121 ? -7.624  8.495   12.646  1   24.72  ? 291 VAL B CB  1 
ATOM   3431 C  CG1 . VAL B 2 121 ? -7.916  7.283   11.757  1   24.35  ? 291 VAL B CG1 1 
ATOM   3432 C  CG2 . VAL B 2 121 ? -7.603  9.774   11.822  1   23.95  ? 291 VAL B CG2 1 
ATOM   3433 N  N   . LEU B 2 122 ? -7.773  7.024   15.447  1   25.45  ? 292 LEU B N   1 
ATOM   3434 C  CA  . LEU B 2 122 ? -7.743  5.766   16.172  1   26.91  ? 292 LEU B CA  1 
ATOM   3435 C  C   . LEU B 2 122 ? -8.931  5.674   17.124  1   28.85  ? 292 LEU B C   1 
ATOM   3436 O  O   . LEU B 2 122 ? -9.541  4.615   17.209  1   29.95  ? 292 LEU B O   1 
ATOM   3437 C  CB  . LEU B 2 122 ? -6.411  5.531   16.89   1   23.51  ? 292 LEU B CB  1 
ATOM   3438 C  CG  . LEU B 2 122 ? -5.197  5.249   15.993  1   21.62  ? 292 LEU B CG  1 
ATOM   3439 C  CD1 . LEU B 2 122 ? -4.064  4.744   16.857  1   21.13  ? 292 LEU B CD1 1 
ATOM   3440 C  CD2 . LEU B 2 122 ? -5.482  4.306   14.829  1   19.38  ? 292 LEU B CD2 1 
ATOM   3441 N  N   . ARG B 2 123 ? -9.255  6.765   17.805  1   28.19  ? 293 ARG B N   1 
ATOM   3442 C  CA  . ARG B 2 123 ? -10.374 6.745   18.777  1   27.95  ? 293 ARG B CA  1 
ATOM   3443 C  C   . ARG B 2 123 ? -11.683 6.578   18.003  1   26.35  ? 293 ARG B C   1 
ATOM   3444 O  O   . ARG B 2 123 ? -12.552 5.841   18.475  1   25.6   ? 293 ARG B O   1 
ATOM   3445 C  CB  . ARG B 2 123 ? -10.344 8.005   19.648  1   31.32  ? 293 ARG B CB  1 
ATOM   3446 C  CG  . ARG B 2 123 ? -9.443  7.917   20.87   1   34.09  ? 293 ARG B CG  1 
ATOM   3447 C  CD  . ARG B 2 123 ? -10.108 8.515   22.094  1   40.84  ? 293 ARG B CD  1 
ATOM   3448 N  NE  . ARG B 2 123 ? -10.079 9.981   22.06   1   58.38  ? 293 ARG B NE  1 
ATOM   3449 C  CZ  . ARG B 2 123 ? -11.103 10.769  22.365  1   71.12  ? 293 ARG B CZ  1 
ATOM   3450 N  NH1 . ARG B 2 123 ? -11.785 10.566  23.476  1   68.57  ? 293 ARG B NH1 1 
ATOM   3451 N  NH2 . ARG B 2 123 ? -11.438 11.76   21.559  1   66.72  ? 293 ARG B NH2 1 
ATOM   3452 N  N   . MET B 2 124 ? -11.803 7.241   16.861  1   24.23  ? 294 MET B N   1 
ATOM   3453 C  CA  . MET B 2 124 ? -12.979 7.067   16.027  1   24.89  ? 294 MET B CA  1 
ATOM   3454 C  C   . MET B 2 124 ? -13.063 5.62    15.536  1   24.76  ? 294 MET B C   1 
ATOM   3455 O  O   . MET B 2 124 ? -14.151 5.061   15.475  1   25.18  ? 294 MET B O   1 
ATOM   3456 C  CB  . MET B 2 124 ? -12.972 7.99    14.809  1   26.06  ? 294 MET B CB  1 
ATOM   3457 C  CG  . MET B 2 124 ? -14.211 7.834   13.927  1   24.2   ? 294 MET B CG  1 
ATOM   3458 S  SD  . MET B 2 124 ? -15.756 8.231   14.773  1   27.88  ? 294 MET B SD  1 
ATOM   3459 C  CE  . MET B 2 124 ? -15.723 10.031  14.863  1   22.4   ? 294 MET B CE  1 
ATOM   3460 N  N   . GLU B 2 125 ? -11.924 5.053   15.128  1   23.48  ? 295 GLU B N   1 
ATOM   3461 C  CA  . GLU B 2 125 ? -11.925 3.661   14.608  1   26.04  ? 295 GLU B CA  1 
ATOM   3462 C  C   . GLU B 2 125 ? -12.607 2.772   15.657  1   28.14  ? 295 GLU B C   1 
ATOM   3463 O  O   . GLU B 2 125 ? -13.492 1.97    15.281  1   27.27  ? 295 GLU B O   1 
ATOM   3464 C  CB  . GLU B 2 125 ? -10.505 3.184   14.298  1   23.69  ? 295 GLU B CB  1 
ATOM   3465 C  CG  . GLU B 2 125 ? -10.329 1.674   14.429  1   24.12  ? 295 GLU B CG  1 
ATOM   3466 C  CD  . GLU B 2 125 ? -9.018  1.128   13.895  1   26.58  ? 295 GLU B CD  1 
ATOM   3467 O  OE1 . GLU B 2 125 ? -8.012  1.176   14.633  1   26.77  ? 295 GLU B OE1 1 
ATOM   3468 O  OE2 . GLU B 2 125 ? -9.004  0.652   12.742  1   31.56  ? 295 GLU B OE2 1 
ATOM   3469 N  N   . HIS B 2 126 ? -12.229 2.943   16.926  1   28.68  ? 296 HIS B N   1 
ATOM   3470 C  CA  . HIS B 2 126 ? -12.813 2.123   18.02   1   34.52  ? 296 HIS B CA  1 
ATOM   3471 C  C   . HIS B 2 126 ? -14.304 2.439   18.161  1   33.7   ? 296 HIS B C   1 
ATOM   3472 O  O   . HIS B 2 126 ? -15.122 1.5     18.229  1   31.24  ? 296 HIS B O   1 
ATOM   3473 C  CB  . HIS B 2 126 ? -12.07  2.394   19.33   1   42     ? 296 HIS B CB  1 
ATOM   3474 C  CG  . HIS B 2 126 ? -12.201 1.288   20.316  1   62.8   ? 296 HIS B CG  1 
ATOM   3475 N  ND1 . HIS B 2 126 ? -11.965 -0.029  19.987  1   69.29  ? 296 HIS B ND1 1 
ATOM   3476 C  CD2 . HIS B 2 126 ? -12.544 1.296   21.608  1   76.28  ? 296 HIS B CD2 1 
ATOM   3477 C  CE1 . HIS B 2 126 ? -12.159 -0.784  21.058  1   84.34  ? 296 HIS B CE1 1 
ATOM   3478 N  NE2 . HIS B 2 126 ? -12.51  0.002   22.052  1   96.87  ? 296 HIS B NE2 1 
ATOM   3479 N  N   . LEU B 2 127 ? -14.644 3.728   18.224  1   29.46  ? 297 LEU B N   1 
ATOM   3480 C  CA  . LEU B 2 127 ? -16.064 4.139   18.368  1   25.39  ? 297 LEU B CA  1 
ATOM   3481 C  C   . LEU B 2 127 ? -16.912 3.394   17.328  1   24.32  ? 297 LEU B C   1 
ATOM   3482 O  O   . LEU B 2 127 ? -17.987 2.88    17.698  1   26.22  ? 297 LEU B O   1 
ATOM   3483 C  CB  . LEU B 2 127 ? -16.155 5.653   18.192  1   23.33  ? 297 LEU B CB  1 
ATOM   3484 C  CG  . LEU B 2 127 ? -17.561 6.257   18.265  1   20.86  ? 297 LEU B CG  1 
ATOM   3485 C  CD1 . LEU B 2 127 ? -18.239 5.892   19.573  1   18.85  ? 297 LEU B CD1 1 
ATOM   3486 C  CD2 . LEU B 2 127 ? -17.508 7.765   18.095  1   19.99  ? 297 LEU B CD2 1 
ATOM   3487 N  N   . VAL B 2 128 ? -16.437 3.323   16.083  1   23.28  ? 298 VAL B N   1 
ATOM   3488 C  CA  . VAL B 2 128 ? -17.2   2.688   15.027  1   22.76  ? 298 VAL B CA  1 
ATOM   3489 C  C   . VAL B 2 128 ? -17.294 1.191   15.304  1   24.07  ? 298 VAL B C   1 
ATOM   3490 O  O   . VAL B 2 128 ? -18.369 0.597   15.207  1   27.41  ? 298 VAL B O   1 
ATOM   3491 C  CB  . VAL B 2 128 ? -16.581 2.979   13.655  1   23.46  ? 298 VAL B CB  1 
ATOM   3492 C  CG1 . VAL B 2 128 ? -17.228 2.145   12.546  1   22.38  ? 298 VAL B CG1 1 
ATOM   3493 C  CG2 . VAL B 2 128 ? -16.663 4.467   13.339  1   22.47  ? 298 VAL B CG2 1 
ATOM   3494 N  N   . LEU B 2 129 ? -16.164 0.574   15.647  1   23.62  ? 299 LEU B N   1 
ATOM   3495 C  CA  . LEU B 2 129 ? -16.196 -0.822  16.047  1   21.69  ? 299 LEU B CA  1 
ATOM   3496 C  C   . LEU B 2 129 ? -17.253 -1.018  17.126  1   21.01  ? 299 LEU B C   1 
ATOM   3497 O  O   . LEU B 2 129 ? -18.02  -1.967  17.06   1   21.56  ? 299 LEU B O   1 
ATOM   3498 C  CB  . LEU B 2 129 ? -14.815 -1.302  16.493  1   22.37  ? 299 LEU B CB  1 
ATOM   3499 C  CG  . LEU B 2 129 ? -13.762 -1.462  15.389  1   21.37  ? 299 LEU B CG  1 
ATOM   3500 C  CD1 . LEU B 2 129 ? -12.411 -1.867  15.947  1   18.24  ? 299 LEU B CD1 1 
ATOM   3501 C  CD2 . LEU B 2 129 ? -14.238 -2.434  14.324  1   21.28  ? 299 LEU B CD2 1 
ATOM   3502 N  N   . LYS B 2 130 ? -17.295 -0.116  18.105  1   22.16  ? 300 LYS B N   1 
ATOM   3503 C  CA  . LYS B 2 130 ? -18.264 -0.234  19.185  1   26.2   ? 300 LYS B CA  1 
ATOM   3504 C  C   . LYS B 2 130 ? -19.695 -0.14   18.655  1   27.59  ? 300 LYS B C   1 
ATOM   3505 O  O   . LYS B 2 130 ? -20.523 -0.991  18.98   1   27.1   ? 300 LYS B O   1 
ATOM   3506 C  CB  . LYS B 2 130 ? -17.984 0.734   20.335  1   31.39  ? 300 LYS B CB  1 
ATOM   3507 C  CG  . LYS B 2 130 ? -17.23  0.063   21.485  1   42.5   ? 300 LYS B CG  1 
ATOM   3508 C  CD  . LYS B 2 130 ? -16.32  0.994   22.281  1   53.23  ? 300 LYS B CD  1 
ATOM   3509 C  CE  . LYS B 2 130 ? -16.077 0.498   23.689  1   58.39  ? 300 LYS B CE  1 
ATOM   3510 N  NZ  . LYS B 2 130 ? -15.023 1.24    24.391  1   57.85  ? 300 LYS B NZ  1 
ATOM   3511 N  N   . VAL B 2 131 ? -19.963 0.881   17.827  1   26.48  ? 301 VAL B N   1 
ATOM   3512 C  CA  . VAL B 2 131 ? -21.297 1.137   17.318  1   25.22  ? 301 VAL B CA  1 
ATOM   3513 C  C   . VAL B 2 131 ? -21.761 -0.018  16.426  1   22.66  ? 301 VAL B C   1 
ATOM   3514 O  O   . VAL B 2 131 ? -22.924 -0.379  16.465  1   22.26  ? 301 VAL B O   1 
ATOM   3515 C  CB  . VAL B 2 131 ? -21.384 2.511   16.621  1   27.89  ? 301 VAL B CB  1 
ATOM   3516 C  CG1 . VAL B 2 131 ? -22.639 2.672   15.743  1   25.28  ? 301 VAL B CG1 1 
ATOM   3517 C  CG2 . VAL B 2 131 ? -21.229 3.649   17.63   1   24.13  ? 301 VAL B CG2 1 
ATOM   3518 N  N   . LEU B 2 132 ? -20.855 -0.607  15.647  1   21.54  ? 302 LEU B N   1 
ATOM   3519 C  CA  . LEU B 2 132 ? -21.203 -1.69   14.741  1   20.3   ? 302 LEU B CA  1 
ATOM   3520 C  C   . LEU B 2 132 ? -21.09  -3.039  15.458  1   21.64  ? 302 LEU B C   1 
ATOM   3521 O  O   . LEU B 2 132 ? -21.464 -4.074  14.905  1   22.05  ? 302 LEU B O   1 
ATOM   3522 C  CB  . LEU B 2 132 ? -20.273 -1.644  13.529  1   20.33  ? 302 LEU B CB  1 
ATOM   3523 C  CG  . LEU B 2 132 ? -20.323 -0.387  12.65   1   23.93  ? 302 LEU B CG  1 
ATOM   3524 C  CD1 . LEU B 2 132 ? -19.544 -0.561  11.358  1   24.62  ? 302 LEU B CD1 1 
ATOM   3525 C  CD2 . LEU B 2 132 ? -21.72  0.088   12.279  1   23.99  ? 302 LEU B CD2 1 
ATOM   3526 N  N   . ALA B 2 133 ? -20.534 -3.043  16.676  1   21.37  ? 303 ALA B N   1 
ATOM   3527 C  CA  . ALA B 2 133 ? -20.28  -4.269  17.43   1   21.14  ? 303 ALA B CA  1 
ATOM   3528 C  C   . ALA B 2 133 ? -19.509 -5.254  16.564  1   21     ? 303 ALA B C   1 
ATOM   3529 O  O   . ALA B 2 133 ? -19.834 -6.443  16.578  1   20.2   ? 303 ALA B O   1 
ATOM   3530 C  CB  . ALA B 2 133 ? -21.547 -4.895  18.019  1   16.13  ? 303 ALA B CB  1 
ATOM   3531 N  N   . PHE B 2 134 ? -18.517 -4.72   15.833  1   21.02  ? 304 PHE B N   1 
ATOM   3532 C  CA  . PHE B 2 134 ? -17.521 -5.498  15.111  1   24.49  ? 304 PHE B CA  1 
ATOM   3533 C  C   . PHE B 2 134 ? -18.196 -6.244  13.975  1   27.48  ? 304 PHE B C   1 
ATOM   3534 O  O   . PHE B 2 134 ? -17.631 -7.145  13.371  1   30.37  ? 304 PHE B O   1 
ATOM   3535 C  CB  . PHE B 2 134 ? -16.767 -6.524  15.965  1   24.07  ? 304 PHE B CB  1 
ATOM   3536 C  CG  . PHE B 2 134 ? -15.595 -5.919  16.706  1   26.46  ? 304 PHE B CG  1 
ATOM   3537 C  CD1 . PHE B 2 134 ? -15.779 -5.253  17.913  1   26.75  ? 304 PHE B CD1 1 
ATOM   3538 C  CD2 . PHE B 2 134 ? -14.312 -5.992  16.169  1   29.11  ? 304 PHE B CD2 1 
ATOM   3539 C  CE1 . PHE B 2 134 ? -14.692 -4.692  18.573  1   28.27  ? 304 PHE B CE1 1 
ATOM   3540 C  CE2 . PHE B 2 134 ? -13.229 -5.425  16.837  1   26.62  ? 304 PHE B CE2 1 
ATOM   3541 C  CZ  . PHE B 2 134 ? -13.419 -4.797  18.044  1   26.76  ? 304 PHE B CZ  1 
ATOM   3542 N  N   . ASP B 2 135 ? -19.412 -5.823  13.678  1   32.09  ? 305 ASP B N   1 
ATOM   3543 C  CA  . ASP B 2 135 ? -20.215 -6.539  12.716  1   34.13  ? 305 ASP B CA  1 
ATOM   3544 C  C   . ASP B 2 135 ? -19.869 -6.037  11.313  1   29.02  ? 305 ASP B C   1 
ATOM   3545 O  O   . ASP B 2 135 ? -20.636 -5.284  10.723  1   28.48  ? 305 ASP B O   1 
ATOM   3546 C  CB  . ASP B 2 135 ? -21.658 -6.393  13.146  1   39.95  ? 305 ASP B CB  1 
ATOM   3547 C  CG  . ASP B 2 135 ? -21.953 -7.186  14.389  1   50.57  ? 305 ASP B CG  1 
ATOM   3548 O  OD1 . ASP B 2 135 ? -21.091 -8.056  14.706  1   63.87  ? 305 ASP B OD1 1 
ATOM   3549 O  OD2 . ASP B 2 135 ? -22.98  -6.85   15.029  1   56.63  ? 305 ASP B OD2 1 
ATOM   3550 N  N   . LEU B 2 136 ? -18.707 -6.461  10.798  1   25.42  ? 306 LEU B N   1 
ATOM   3551 C  CA  . LEU B 2 136 ? -18.057 -5.826  9.658   1   27.07  ? 306 LEU B CA  1 
ATOM   3552 C  C   . LEU B 2 136 ? -18.163 -6.623  8.355   1   25.88  ? 306 LEU B C   1 
ATOM   3553 O  O   . LEU B 2 136 ? -17.927 -6.065  7.291   1   28.56  ? 306 LEU B O   1 
ATOM   3554 C  CB  . LEU B 2 136 ? -16.587 -5.592  9.988   1   27.15  ? 306 LEU B CB  1 
ATOM   3555 C  CG  . LEU B 2 136 ? -16.282 -4.693  11.182  1   28.66  ? 306 LEU B CG  1 
ATOM   3556 C  CD1 . LEU B 2 136 ? -14.828 -4.299  11.074  1   30.36  ? 306 LEU B CD1 1 
ATOM   3557 C  CD2 . LEU B 2 136 ? -17.178 -3.47   11.25   1   26.65  ? 306 LEU B CD2 1 
ATOM   3558 N  N   . ALA B 2 137 ? -18.431 -7.932  8.421   1   27.06  ? 307 ALA B N   1 
ATOM   3559 C  CA  . ALA B 2 137 ? -18.549 -8.733  7.202   1   28.05  ? 307 ALA B CA  1 
ATOM   3560 C  C   . ALA B 2 137 ? -19.909 -8.521  6.538   1   25.71  ? 307 ALA B C   1 
ATOM   3561 O  O   . ALA B 2 137 ? -20.76  -9.398  6.56    1   30.08  ? 307 ALA B O   1 
ATOM   3562 C  CB  . ALA B 2 137 ? -18.291 -10.196 7.483   1   23     ? 307 ALA B CB  1 
ATOM   3563 N  N   . ALA B 2 138 ? -20.092 -7.339  5.964   1   25.53  ? 308 ALA B N   1 
ATOM   3564 C  CA  . ALA B 2 138 ? -21.36  -6.902  5.415   1   28.49  ? 308 ALA B CA  1 
ATOM   3565 C  C   . ALA B 2 138 ? -21.411 -7.276  3.947   1   28.5   ? 308 ALA B C   1 
ATOM   3566 O  O   . ALA B 2 138 ? -20.421 -7.101  3.243   1   28.56  ? 308 ALA B O   1 
ATOM   3567 C  CB  . ALA B 2 138 ? -21.477 -5.391  5.544   1   28.59  ? 308 ALA B CB  1 
ATOM   3568 N  N   . PRO B 2 139 ? -22.567 -7.769  3.453   1   30.8   ? 309 PRO B N   1 
ATOM   3569 C  CA  . PRO B 2 139 ? -22.768 -8      2.023   1   31.95  ? 309 PRO B CA  1 
ATOM   3570 C  C   . PRO B 2 139 ? -22.767 -6.649  1.346   1   30.64  ? 309 PRO B C   1 
ATOM   3571 O  O   . PRO B 2 139 ? -23.455 -5.755  1.804   1   35.05  ? 309 PRO B O   1 
ATOM   3572 C  CB  . PRO B 2 139 ? -24.168 -8.603  1.936   1   29.23  ? 309 PRO B CB  1 
ATOM   3573 C  CG  . PRO B 2 139 ? -24.406 -9.158  3.304   1   29.37  ? 309 PRO B CG  1 
ATOM   3574 C  CD  . PRO B 2 139 ? -23.755 -8.135  4.236   1   29.56  ? 309 PRO B CD  1 
ATOM   3575 N  N   . THR B 2 140 ? -22.032 -6.555  0.24    1   31.55  ? 310 THR B N   1 
ATOM   3576 C  CA  . THR B 2 140 ? -21.966 -5.366  -0.597  1   30.57  ? 310 THR B CA  1 
ATOM   3577 C  C   . THR B 2 140 ? -22.624 -5.647  -1.945  1   32.49  ? 310 THR B C   1 
ATOM   3578 O  O   . THR B 2 140 ? -22.756 -6.807  -2.361  1   34.4   ? 310 THR B O   1 
ATOM   3579 C  CB  . THR B 2 140 ? -20.509 -4.952  -0.818  1   28.55  ? 310 THR B CB  1 
ATOM   3580 O  OG1 . THR B 2 140 ? -19.81  -5.962  -1.552  1   30.29  ? 310 THR B OG1 1 
ATOM   3581 C  CG2 . THR B 2 140 ? -19.77  -4.685  0.477   1   25.36  ? 310 THR B CG2 1 
ATOM   3582 N  N   . ILE B 2 141 ? -22.952 -4.553  -2.645  1   27.96  ? 311 ILE B N   1 
ATOM   3583 C  CA  . ILE B 2 141 ? -23.406 -4.613  -4.017  1   27.78  ? 311 ILE B CA  1 
ATOM   3584 C  C   . ILE B 2 141 ? -22.454 -5.502  -4.813  1   29.83  ? 311 ILE B C   1 
ATOM   3585 O  O   . ILE B 2 141 ? -22.924 -6.408  -5.513  1   33.29  ? 311 ILE B O   1 
ATOM   3586 C  CB  . ILE B 2 141 ? -23.55  -3.2    -4.613  1   27.87  ? 311 ILE B CB  1 
ATOM   3587 C  CG1 . ILE B 2 141 ? -24.708 -2.407  -4.013  1   24.92  ? 311 ILE B CG1 1 
ATOM   3588 C  CG2 . ILE B 2 141 ? -23.687 -3.251  -6.122  1   23.52  ? 311 ILE B CG2 1 
ATOM   3589 C  CD1 . ILE B 2 141 ? -24.618 -0.905  -4.275  1   21.55  ? 311 ILE B CD1 1 
ATOM   3590 N  N   . ASN B 2 142 ? -21.137 -5.295  -4.638  1   30.23  ? 312 ASN B N   1 
ATOM   3591 C  CA  . ASN B 2 142 ? -20.129 -6.017  -5.412  1   32.13  ? 312 ASN B CA  1 
ATOM   3592 C  C   . ASN B 2 142 ? -20.19  -7.519  -5.184  1   32.32  ? 312 ASN B C   1 
ATOM   3593 O  O   . ASN B 2 142 ? -19.963 -8.274  -6.141  1   34.59  ? 312 ASN B O   1 
ATOM   3594 C  CB  . ASN B 2 142 ? -18.686 -5.606  -5.127  1   34.16  ? 312 ASN B CB  1 
ATOM   3595 C  CG  . ASN B 2 142 ? -18.272 -4.43   -5.974  1   45.05  ? 312 ASN B CG  1 
ATOM   3596 O  OD1 . ASN B 2 142 ? -19.111 -3.728  -6.552  1   48.04  ? 312 ASN B OD1 1 
ATOM   3597 N  ND2 . ASN B 2 142 ? -16.98  -4.171  -6.044  1   55.14  ? 312 ASN B ND2 1 
ATOM   3598 N  N   . GLN B 2 143 ? -20.39  -7.926  -3.914  1   30.92  ? 313 GLN B N   1 
ATOM   3599 C  CA  . GLN B 2 143 ? -20.474 -9.343  -3.573  1   34.11  ? 313 GLN B CA  1 
ATOM   3600 C  C   . GLN B 2 143 ? -21.583 -10.056 -4.363  1   32     ? 313 GLN B C   1 
ATOM   3601 O  O   . GLN B 2 143 ? -21.392 -11.2   -4.747  1   29.94  ? 313 GLN B O   1 
ATOM   3602 C  CB  . GLN B 2 143 ? -20.706 -9.531  -2.079  1   33.45  ? 313 GLN B CB  1 
ATOM   3603 C  CG  . GLN B 2 143 ? -19.421 -9.588  -1.265  1   31.01  ? 313 GLN B CG  1 
ATOM   3604 C  CD  . GLN B 2 143 ? -19.693 -9.675  0.221   1   34.49  ? 313 GLN B CD  1 
ATOM   3605 O  OE1 . GLN B 2 143 ? -20.115 -10.719 0.748   1   30.53  ? 313 GLN B OE1 1 
ATOM   3606 N  NE2 . GLN B 2 143 ? -19.472 -8.559  0.906   1   31.75  ? 313 GLN B NE2 1 
ATOM   3607 N  N   . PHE B 2 144 ? -22.707 -9.365  -4.641  1   29.47  ? 314 PHE B N   1 
ATOM   3608 C  CA  . PHE B 2 144 ? -23.792 -9.884  -5.456  1   25.56  ? 314 PHE B CA  1 
ATOM   3609 C  C   . PHE B 2 144 ? -23.486 -9.817  -6.952  1   25.91  ? 314 PHE B C   1 
ATOM   3610 O  O   . PHE B 2 144 ? -23.693 -10.816 -7.659  1   26.15  ? 314 PHE B O   1 
ATOM   3611 C  CB  . PHE B 2 144 ? -25.089 -9.159  -5.157  1   22.52  ? 314 PHE B CB  1 
ATOM   3612 C  CG  . PHE B 2 144 ? -25.682 -9.572  -3.83   1   24.08  ? 314 PHE B CG  1 
ATOM   3613 C  CD1 . PHE B 2 144 ? -26.264 -10.828 -3.676  1   24.98  ? 314 PHE B CD1 1 
ATOM   3614 C  CD2 . PHE B 2 144 ? -25.678 -8.694  -2.744  1   24.18  ? 314 PHE B CD2 1 
ATOM   3615 C  CE1 . PHE B 2 144 ? -26.8   -11.219 -2.45   1   24.31  ? 314 PHE B CE1 1 
ATOM   3616 C  CE2 . PHE B 2 144 ? -26.256 -9.069  -1.532  1   23.84  ? 314 PHE B CE2 1 
ATOM   3617 C  CZ  . PHE B 2 144 ? -26.822 -10.325 -1.393  1   25.4   ? 314 PHE B CZ  1 
ATOM   3618 N  N   . LEU B 2 145 ? -23.005 -8.655  -7.423  1   22.9   ? 315 LEU B N   1 
ATOM   3619 C  CA  . LEU B 2 145 ? -22.601 -8.488  -8.816  1   22.38  ? 315 LEU B CA  1 
ATOM   3620 C  C   . LEU B 2 145 ? -21.717 -9.644  -9.305  1   24.64  ? 315 LEU B C   1 
ATOM   3621 O  O   . LEU B 2 145 ? -21.956 -10.224 -10.355 1   24.33  ? 315 LEU B O   1 
ATOM   3622 C  CB  . LEU B 2 145 ? -21.875 -7.164  -8.982  1   19.9   ? 315 LEU B CB  1 
ATOM   3623 C  CG  . LEU B 2 145 ? -22.774 -5.941  -9.171  1   20.37  ? 315 LEU B CG  1 
ATOM   3624 C  CD1 . LEU B 2 145 ? -21.937 -4.718  -9.398  1   18.6   ? 315 LEU B CD1 1 
ATOM   3625 C  CD2 . LEU B 2 145 ? -23.724 -6.151  -10.329 1   19.66  ? 315 LEU B CD2 1 
ATOM   3626 N  N   . THR B 2 146 ? -20.693 -10.004 -8.531  1   24.26  ? 316 THR B N   1 
ATOM   3627 C  CA  . THR B 2 146 ? -19.745 -10.992 -9.006  1   26.23  ? 316 THR B CA  1 
ATOM   3628 C  C   . THR B 2 146 ? -20.424 -12.341 -9.216  1   26.48  ? 316 THR B C   1 
ATOM   3629 O  O   . THR B 2 146 ? -20.002 -13.121 -10.064 1   30.8   ? 316 THR B O   1 
ATOM   3630 C  CB  . THR B 2 146 ? -18.514 -11.056 -8.096  1   27.12  ? 316 THR B CB  1 
ATOM   3631 O  OG1 . THR B 2 146 ? -18.96  -11.365 -6.775  1   29.22  ? 316 THR B OG1 1 
ATOM   3632 C  CG2 . THR B 2 146 ? -17.728 -9.755  -8.094  1   22.74  ? 316 THR B CG2 1 
ATOM   3633 N  N   . GLN B 2 147 ? -21.473 -12.628 -8.441  1   29.42  ? 317 GLN B N   1 
ATOM   3634 C  CA  . GLN B 2 147 ? -22.175 -13.897 -8.595  1   28.94  ? 317 GLN B CA  1 
ATOM   3635 C  C   . GLN B 2 147 ? -23.124 -13.83  -9.786  1   29.02  ? 317 GLN B C   1 
ATOM   3636 O  O   . GLN B 2 147 ? -23.321 -14.823 -10.491 1   31.08  ? 317 GLN B O   1 
ATOM   3637 C  CB  . GLN B 2 147 ? -23.012 -14.227 -7.369  1   25.73  ? 317 GLN B CB  1 
ATOM   3638 C  CG  . GLN B 2 147 ? -22.184 -14.257 -6.103  1   28.12  ? 317 GLN B CG  1 
ATOM   3639 C  CD  . GLN B 2 147 ? -22.879 -14.959 -4.968  1   29.6   ? 317 GLN B CD  1 
ATOM   3640 O  OE1 . GLN B 2 147 ? -22.484 -14.785 -3.814  1   35.7   ? 317 GLN B OE1 1 
ATOM   3641 N  NE2 . GLN B 2 147 ? -23.908 -15.74  -5.269  1   27.06  ? 317 GLN B NE2 1 
ATOM   3642 N  N   . TYR B 2 148 ? -23.72  -12.649 -9.974  1   25.62  ? 318 TYR B N   1 
ATOM   3643 C  CA  . TYR B 2 148 ? -24.625 -12.452 -11.08  1   25.43  ? 318 TYR B CA  1 
ATOM   3644 C  C   . TYR B 2 148 ? -23.852 -12.586 -12.383 1   25.68  ? 318 TYR B C   1 
ATOM   3645 O  O   . TYR B 2 148 ? -24.392 -13.094 -13.36  1   29.78  ? 318 TYR B O   1 
ATOM   3646 C  CB  . TYR B 2 148 ? -25.266 -11.072 -10.985 1   26.12  ? 318 TYR B CB  1 
ATOM   3647 C  CG  . TYR B 2 148 ? -26.185 -10.826 -9.801  1   25.08  ? 318 TYR B CG  1 
ATOM   3648 C  CD1 . TYR B 2 148 ? -26.553 -11.84  -8.935  1   23.95  ? 318 TYR B CD1 1 
ATOM   3649 C  CD2 . TYR B 2 148 ? -26.7   -9.556  -9.57   1   26.76  ? 318 TYR B CD2 1 
ATOM   3650 C  CE1 . TYR B 2 148 ? -27.406 -11.588 -7.876  1   26.25  ? 318 TYR B CE1 1 
ATOM   3651 C  CE2 . TYR B 2 148 ? -27.558 -9.296  -8.512  1   27.25  ? 318 TYR B CE2 1 
ATOM   3652 C  CZ  . TYR B 2 148 ? -27.933 -10.322 -7.667  1   26.72  ? 318 TYR B CZ  1 
ATOM   3653 O  OH  . TYR B 2 148 ? -28.782 -10.092 -6.616  1   25.38  ? 318 TYR B OH  1 
ATOM   3654 N  N   . PHE B 2 149 ? -22.609 -12.102 -12.394 1   25.32  ? 319 PHE B N   1 
ATOM   3655 C  CA  . PHE B 2 149 ? -21.759 -12.154 -13.572 1   27.6   ? 319 PHE B CA  1 
ATOM   3656 C  C   . PHE B 2 149 ? -21.571 -13.593 -14.062 1   28.93  ? 319 PHE B C   1 
ATOM   3657 O  O   . PHE B 2 149 ? -21.356 -13.804 -15.253 1   28.19  ? 319 PHE B O   1 
ATOM   3658 C  CB  . PHE B 2 149 ? -20.38  -11.552 -13.304 1   27.52  ? 319 PHE B CB  1 
ATOM   3659 C  CG  . PHE B 2 149 ? -20.336 -10.057 -13.065 1   30.65  ? 319 PHE B CG  1 
ATOM   3660 C  CD1 . PHE B 2 149 ? -21.424 -9.244  -13.375 1   29.93  ? 319 PHE B CD1 1 
ATOM   3661 C  CD2 . PHE B 2 149 ? -19.196 -9.473  -12.515 1   30.39  ? 319 PHE B CD2 1 
ATOM   3662 C  CE1 . PHE B 2 149 ? -21.368 -7.88   -13.147 1   28.58  ? 319 PHE B CE1 1 
ATOM   3663 C  CE2 . PHE B 2 149 ? -19.151 -8.106  -12.287 1   28.37  ? 319 PHE B CE2 1 
ATOM   3664 C  CZ  . PHE B 2 149 ? -20.227 -7.315  -12.611 1   29.27  ? 319 PHE B CZ  1 
ATOM   3665 N  N   . LEU B 2 150 ? -21.624 -14.575 -13.154 1   28.74  ? 320 LEU B N   1 
ATOM   3666 C  CA  . LEU B 2 150 ? -21.406 -15.959 -13.541 1   31.27  ? 320 LEU B CA  1 
ATOM   3667 C  C   . LEU B 2 150 ? -22.502 -16.462 -14.481 1   33.77  ? 320 LEU B C   1 
ATOM   3668 O  O   . LEU B 2 150 ? -22.341 -17.523 -15.082 1   34.01  ? 320 LEU B O   1 
ATOM   3669 C  CB  . LEU B 2 150 ? -21.257 -16.838 -12.303 1   31.6   ? 320 LEU B CB  1 
ATOM   3670 C  CG  . LEU B 2 150 ? -20.022 -16.522 -11.446 1   34.89  ? 320 LEU B CG  1 
ATOM   3671 C  CD1 . LEU B 2 150 ? -19.918 -17.45  -10.263 1   35.12  ? 320 LEU B CD1 1 
ATOM   3672 C  CD2 . LEU B 2 150 ? -18.712 -16.561 -12.219 1   30.79  ? 320 LEU B CD2 1 
ATOM   3673 N  N   . HIS B 2 151 ? -23.571 -15.67  -14.651 1   32.68  ? 321 HIS B N   1 
ATOM   3674 C  CA  . HIS B 2 151 ? -24.735 -16.067 -15.426 1   30.85  ? 321 HIS B CA  1 
ATOM   3675 C  C   . HIS B 2 151 ? -24.688 -15.478 -16.829 1   33.45  ? 321 HIS B C   1 
ATOM   3676 O  O   . HIS B 2 151 ? -25.609 -15.71  -17.602 1   38.81  ? 321 HIS B O   1 
ATOM   3677 C  CB  . HIS B 2 151 ? -26.033 -15.636 -14.725 1   29.06  ? 321 HIS B CB  1 
ATOM   3678 C  CG  . HIS B 2 151 ? -26.291 -16.421 -13.492 1   28.14  ? 321 HIS B CG  1 
ATOM   3679 N  ND1 . HIS B 2 151 ? -27.368 -17.268 -13.354 1   27.15  ? 321 HIS B ND1 1 
ATOM   3680 C  CD2 . HIS B 2 151 ? -25.585 -16.515 -12.351 1   25.92  ? 321 HIS B CD2 1 
ATOM   3681 C  CE1 . HIS B 2 151 ? -27.293 -17.86  -12.168 1   24.96  ? 321 HIS B CE1 1 
ATOM   3682 N  NE2 . HIS B 2 151 ? -26.219 -17.421 -11.551 1   24.58  ? 321 HIS B NE2 1 
ATOM   3683 N  N   . GLN B 2 152 ? -23.651 -14.7   -17.11  1   38.09  ? 322 GLN B N   1 
ATOM   3684 C  CA  . GLN B 2 152 ? -23.479 -14.1   -18.452 1   40.61  ? 322 GLN B CA  1 
ATOM   3685 C  C   . GLN B 2 152 ? -23.088 -15.187 -19.448 1   46.02  ? 322 GLN B C   1 
ATOM   3686 O  O   . GLN B 2 152 ? -22.218 -16.011 -19.113 1   37.79  ? 322 GLN B O   1 
ATOM   3687 C  CB  . GLN B 2 152 ? -22.328 -13.113 -18.55  1   35.39  ? 322 GLN B CB  1 
ATOM   3688 C  CG  . GLN B 2 152 ? -22.39  -11.905 -17.628 1   35.3   ? 322 GLN B CG  1 
ATOM   3689 C  CD  . GLN B 2 152 ? -21.093 -11.13  -17.658 1   38.12  ? 322 GLN B CD  1 
ATOM   3690 O  OE1 . GLN B 2 152 ? -20.947 -10.144 -18.386 1   38.69  ? 322 GLN B OE1 1 
ATOM   3691 N  NE2 . GLN B 2 152 ? -20.121 -11.604 -16.896 1   33.31  ? 322 GLN B NE2 1 
ATOM   3692 N  N   . GLN B 2 153 ? -23.69  -15.15  -20.636 1   54.86  ? 323 GLN B N   1 
ATOM   3693 C  CA  . GLN B 2 153 ? -23.381 -16.14  -21.697 1   64.31  ? 323 GLN B CA  1 
ATOM   3694 C  C   . GLN B 2 153 ? -23.236 -15.419 -23.048 1   58.92  ? 323 GLN B C   1 
ATOM   3695 O  O   . GLN B 2 153 ? -24.278 -15.119 -23.661 1   52.68  ? 323 GLN B O   1 
ATOM   3696 C  CB  . GLN B 2 153 ? -24.501 -17.177 -21.774 1   75.24  ? 323 GLN B CB  1 
ATOM   3697 C  CG  . GLN B 2 153 ? -24.229 -18.314 -22.752 1   94.67  ? 323 GLN B CG  1 
ATOM   3698 C  CD  . GLN B 2 153 ? -23.042 -19.172 -22.372 1   105.69 ? 323 GLN B CD  1 
ATOM   3699 O  OE1 . GLN B 2 153 ? -23.005 -19.787 -21.3   1   113.35 ? 323 GLN B OE1 1 
ATOM   3700 N  NE2 . GLN B 2 153 ? -22.056 -19.23  -23.255 1   100.39 ? 323 GLN B NE2 1 
ATOM   3701 N  N   . PRO B 2 154 ? -22.011 -15.126 -23.542 1   50.13  ? 324 PRO B N   1 
ATOM   3702 C  CA  . PRO B 2 154 ? -20.792 -15.313 -22.769 1   41     ? 324 PRO B CA  1 
ATOM   3703 C  C   . PRO B 2 154 ? -20.412 -14.131 -21.892 1   35.37  ? 324 PRO B C   1 
ATOM   3704 O  O   . PRO B 2 154 ? -21.12  -13.113 -21.897 1   31.9   ? 324 PRO B O   1 
ATOM   3705 C  CB  . PRO B 2 154 ? -19.816 -15.494 -23.919 1   40.83  ? 324 PRO B CB  1 
ATOM   3706 C  CG  . PRO B 2 154 ? -20.264 -14.477 -24.928 1   36.83  ? 324 PRO B CG  1 
ATOM   3707 C  CD  . PRO B 2 154 ? -21.772 -14.589 -24.869 1   40.07  ? 324 PRO B CD  1 
ATOM   3708 N  N   . ALA B 2 155 ? -19.306 -14.258 -21.161 1   30.44  ? 325 ALA B N   1 
ATOM   3709 C  CA  . ALA B 2 155 ? -18.856 -13.177 -20.256 1   28.32  ? 325 ALA B CA  1 
ATOM   3710 C  C   . ALA B 2 155 ? -18.469 -11.942 -21.058 1   30.11  ? 325 ALA B C   1 
ATOM   3711 O  O   . ALA B 2 155 ? -17.962 -12.086 -22.183 1   32.93  ? 325 ALA B O   1 
ATOM   3712 C  CB  . ALA B 2 155 ? -17.72  -13.657 -19.417 1   26.14  ? 325 ALA B CB  1 
ATOM   3713 N  N   . ASN B 2 156 ? -18.672 -10.764 -20.481 1   28.69  ? 326 ASN B N   1 
ATOM   3714 C  CA  . ASN B 2 156 ? -18.433 -9.535  -21.208 1   27.43  ? 326 ASN B CA  1 
ATOM   3715 C  C   . ASN B 2 156 ? -17.973 -8.488  -20.2   1   30.97  ? 326 ASN B C   1 
ATOM   3716 O  O   . ASN B 2 156 ? -18.726 -8.097  -19.312 1   34.47  ? 326 ASN B O   1 
ATOM   3717 C  CB  . ASN B 2 156 ? -19.656 -9.155  -22.032 1   25.55  ? 326 ASN B CB  1 
ATOM   3718 C  CG  . ASN B 2 156 ? -19.448 -7.912  -22.864 1   27.41  ? 326 ASN B CG  1 
ATOM   3719 O  OD1 . ASN B 2 156 ? -18.991 -6.872  -22.356 1   30.15  ? 326 ASN B OD1 1 
ATOM   3720 N  ND2 . ASN B 2 156 ? -19.835 -7.986  -24.13  1   22.8   ? 326 ASN B ND2 1 
ATOM   3721 N  N   . CYS B 2 157 ? -16.73  -8.039  -20.386 1   33.43  ? 327 CYS B N   1 
ATOM   3722 C  CA  . CYS B 2 157 ? -15.989 -7.156  -19.502 1   33.46  ? 327 CYS B CA  1 
ATOM   3723 C  C   . CYS B 2 157 ? -16.637 -5.785  -19.442 1   29.93  ? 327 CYS B C   1 
ATOM   3724 O  O   . CYS B 2 157 ? -16.665 -5.181  -18.381 1   29.34  ? 327 CYS B O   1 
ATOM   3725 C  CB  . CYS B 2 157 ? -14.577 -6.945  -20.04  1   45.14  ? 327 CYS B CB  1 
ATOM   3726 S  SG  . CYS B 2 157 ? -13.67  -8.507  -20.172 1   72.59  ? 327 CYS B SG  1 
ATOM   3727 N  N   . LYS B 2 158 ? -17.079 -5.293  -20.6   1   28.49  ? 328 LYS B N   1 
ATOM   3728 C  CA  . LYS B 2 158 ? -17.83  -4.057  -20.679 1   29.3   ? 328 LYS B CA  1 
ATOM   3729 C  C   . LYS B 2 158 ? -19.077 -4.175  -19.808 1   25.71  ? 328 LYS B C   1 
ATOM   3730 O  O   . LYS B 2 158 ? -19.409 -3.252  -19.087 1   24.23  ? 328 LYS B O   1 
ATOM   3731 C  CB  . LYS B 2 158 ? -18.141 -3.689  -22.137 1   31.54  ? 328 LYS B CB  1 
ATOM   3732 C  CG  . LYS B 2 158 ? -17.018 -2.943  -22.822 1   35.23  ? 328 LYS B CG  1 
ATOM   3733 C  CD  . LYS B 2 158 ? -16.903 -3.357  -24.282 1   52.24  ? 328 LYS B CD  1 
ATOM   3734 C  CE  . LYS B 2 158 ? -18.117 -3.198  -25.164 1   60.3   ? 328 LYS B CE  1 
ATOM   3735 N  NZ  . LYS B 2 158 ? -18.466 -1.819  -25.528 1   55.54  ? 328 LYS B NZ  1 
ATOM   3736 N  N   . VAL B 2 159 ? -19.778 -5.305  -19.885 1   26.9   ? 329 VAL B N   1 
ATOM   3737 C  CA  . VAL B 2 159 ? -20.933 -5.516  -19.022 1   25.49  ? 329 VAL B CA  1 
ATOM   3738 C  C   . VAL B 2 159 ? -20.517 -5.504  -17.548 1   22.66  ? 329 VAL B C   1 
ATOM   3739 O  O   . VAL B 2 159 ? -21.073 -4.743  -16.758 1   22.62  ? 329 VAL B O   1 
ATOM   3740 C  CB  . VAL B 2 159 ? -21.745 -6.763  -19.406 1   23.32  ? 329 VAL B CB  1 
ATOM   3741 C  CG1 . VAL B 2 159 ? -22.818 -7.041  -18.365 1   21.88  ? 329 VAL B CG1 1 
ATOM   3742 C  CG2 . VAL B 2 159 ? -22.374 -6.583  -20.783 1   22.92  ? 329 VAL B CG2 1 
ATOM   3743 N  N   . GLU B 2 160 ? -19.477 -6.27   -17.215 1   22.28  ? 330 GLU B N   1 
ATOM   3744 C  CA  . GLU B 2 160 ? -19.01  -6.347  -15.835 1   26.43  ? 330 GLU B CA  1 
ATOM   3745 C  C   . GLU B 2 160 ? -18.621 -4.973  -15.31  1   26.57  ? 330 GLU B C   1 
ATOM   3746 O  O   . GLU B 2 160 ? -19.192 -4.546  -14.316 1   28.11  ? 330 GLU B O   1 
ATOM   3747 C  CB  . GLU B 2 160 ? -17.903 -7.367  -15.605 1   25.09  ? 330 GLU B CB  1 
ATOM   3748 C  CG  . GLU B 2 160 ? -18.416 -8.784  -15.834 1   26.94  ? 330 GLU B CG  1 
ATOM   3749 C  CD  . GLU B 2 160 ? -17.346 -9.849  -15.798 1   29.64  ? 330 GLU B CD  1 
ATOM   3750 O  OE1 . GLU B 2 160 ? -16.228 -9.548  -15.383 1   34.63  ? 330 GLU B OE1 1 
ATOM   3751 O  OE2 . GLU B 2 160 ? -17.621 -10.981 -16.184 1   34.53  ? 330 GLU B OE2 1 
ATOM   3752 N  N   . SER B 2 161 ? -17.716 -4.266  -16.01  1   26.31  ? 331 SER B N   1 
ATOM   3753 C  CA  . SER B 2 161 ? -17.248 -2.954  -15.57  1   24.81  ? 331 SER B CA  1 
ATOM   3754 C  C   . SER B 2 161 ? -18.386 -1.934  -15.491 1   26.46  ? 331 SER B C   1 
ATOM   3755 O  O   . SER B 2 161 ? -18.38  -1.077  -14.599 1   25.75  ? 331 SER B O   1 
ATOM   3756 C  CB  . SER B 2 161 ? -16.125 -2.451  -16.399 1   23.84  ? 331 SER B CB  1 
ATOM   3757 O  OG  . SER B 2 161 ? -14.97  -3.23   -16.147 1   27.32  ? 331 SER B OG  1 
ATOM   3758 N  N   . LEU B 2 162 ? -19.356 -2.03   -16.419 1   25.53  ? 332 LEU B N   1 
ATOM   3759 C  CA  . LEU B 2 162 ? -20.408 -1.027  -16.477 1   25.47  ? 332 LEU B CA  1 
ATOM   3760 C  C   . LEU B 2 162 ? -21.353 -1.224  -15.292 1   25.57  ? 332 LEU B C   1 
ATOM   3761 O  O   . LEU B 2 162 ? -21.891 -0.257  -14.758 1   25.23  ? 332 LEU B O   1 
ATOM   3762 C  CB  . LEU B 2 162 ? -21.175 -1.03   -17.797 1   23.31  ? 332 LEU B CB  1 
ATOM   3763 C  CG  . LEU B 2 162 ? -22.363 -0.066  -17.851 1   22.36  ? 332 LEU B CG  1 
ATOM   3764 C  CD1 . LEU B 2 162 ? -21.89  1.365   -17.675 1   21.25  ? 332 LEU B CD1 1 
ATOM   3765 C  CD2 . LEU B 2 162 ? -23.161 -0.202  -19.143 1   23.04  ? 332 LEU B CD2 1 
ATOM   3766 N  N   . ALA B 2 163 ? -21.567 -2.491  -14.927 1   23.1   ? 333 ALA B N   1 
ATOM   3767 C  CA  . ALA B 2 163 ? -22.433 -2.806  -13.817 1   22.35  ? 333 ALA B CA  1 
ATOM   3768 C  C   . ALA B 2 163 ? -21.794 -2.33   -12.516 1   24.45  ? 333 ALA B C   1 
ATOM   3769 O  O   . ALA B 2 163 ? -22.509 -1.792  -11.673 1   24.39  ? 333 ALA B O   1 
ATOM   3770 C  CB  . ALA B 2 163 ? -22.74  -4.274  -13.795 1   19.85  ? 333 ALA B CB  1 
ATOM   3771 N  N   . MET B 2 164 ? -20.475 -2.562  -12.359 1   25.53  ? 334 MET B N   1 
ATOM   3772 C  CA  . MET B 2 164 ? -19.693 -2.085  -11.226 1   25.71  ? 334 MET B CA  1 
ATOM   3773 C  C   . MET B 2 164 ? -19.865 -0.563  -11.083 1   26.17  ? 334 MET B C   1 
ATOM   3774 O  O   . MET B 2 164 ? -20.125 -0.046  -9.999  1   27.41  ? 334 MET B O   1 
ATOM   3775 C  CB  . MET B 2 164 ? -18.21  -2.418  -11.439 1   31.42  ? 334 MET B CB  1 
ATOM   3776 C  CG  . MET B 2 164 ? -17.787 -3.853  -11.182 1   35.79  ? 334 MET B CG  1 
ATOM   3777 S  SD  . MET B 2 164 ? -17.97  -4.163  -9.415  1   50.24  ? 334 MET B SD  1 
ATOM   3778 C  CE  . MET B 2 164 ? -18.115 -5.952  -9.325  1   50.07  ? 334 MET B CE  1 
ATOM   3779 N  N   . PHE B 2 165 ? -19.737 0.165   -12.197 1   26.42  ? 335 PHE B N   1 
ATOM   3780 C  CA  . PHE B 2 165 ? -19.83  1.617   -12.217 1   26.31  ? 335 PHE B CA  1 
ATOM   3781 C  C   . PHE B 2 165 ? -21.206 2.09    -11.753 1   27.74  ? 335 PHE B C   1 
ATOM   3782 O  O   . PHE B 2 165 ? -21.331 2.949   -10.883 1   28.64  ? 335 PHE B O   1 
ATOM   3783 C  CB  . PHE B 2 165 ? -19.584 2.017   -13.668 1   26.37  ? 335 PHE B CB  1 
ATOM   3784 C  CG  . PHE B 2 165 ? -19.913 3.451   -14.041 1   25.84  ? 335 PHE B CG  1 
ATOM   3785 C  CD1 . PHE B 2 165 ? -19.211 4.509   -13.483 1   25.3   ? 335 PHE B CD1 1 
ATOM   3786 C  CD2 . PHE B 2 165 ? -20.886 3.727   -14.998 1   26.37  ? 335 PHE B CD2 1 
ATOM   3787 C  CE1 . PHE B 2 165 ? -19.479 5.817   -13.868 1   26.85  ? 335 PHE B CE1 1 
ATOM   3788 C  CE2 . PHE B 2 165 ? -21.155 5.034   -15.386 1   25.93  ? 335 PHE B CE2 1 
ATOM   3789 C  CZ  . PHE B 2 165 ? -20.448 6.078   -14.818 1   26.59  ? 335 PHE B CZ  1 
ATOM   3790 N  N   . LEU B 2 166 ? -22.257 1.528   -12.345 1   26.85  ? 336 LEU B N   1 
ATOM   3791 C  CA  . LEU B 2 166 ? -23.6   1.887   -11.938 1   27.14  ? 336 LEU B CA  1 
ATOM   3792 C  C   . LEU B 2 166 ? -23.763 1.614   -10.439 1   29.75  ? 336 LEU B C   1 
ATOM   3793 O  O   . LEU B 2 166 ? -24.294 2.44    -9.699  1   29.62  ? 336 LEU B O   1 
ATOM   3794 C  CB  . LEU B 2 166 ? -24.566 1.096   -12.816 1   23.93  ? 336 LEU B CB  1 
ATOM   3795 C  CG  . LEU B 2 166 ? -24.575 1.492   -14.297 1   21.67  ? 336 LEU B CG  1 
ATOM   3796 C  CD1 . LEU B 2 166 ? -25.492 0.597   -15.107 1   19.78  ? 336 LEU B CD1 1 
ATOM   3797 C  CD2 . LEU B 2 166 ? -24.969 2.951   -14.472 1   19.57  ? 336 LEU B CD2 1 
ATOM   3798 N  N   . GLY B 2 167 ? -23.267 0.457   -9.993  1   29.17  ? 337 GLY B N   1 
ATOM   3799 C  CA  . GLY B 2 167 ? -23.283 0.092   -8.591  1   27.04  ? 337 GLY B CA  1 
ATOM   3800 C  C   . GLY B 2 167 ? -22.658 1.185   -7.742  1   28.35  ? 337 GLY B C   1 
ATOM   3801 O  O   . GLY B 2 167 ? -23.237 1.589   -6.738  1   30.17  ? 337 GLY B O   1 
ATOM   3802 N  N   . GLU B 2 168 ? -21.471 1.644   -8.151  1   30.74  ? 338 GLU B N   1 
ATOM   3803 C  CA  . GLU B 2 168 ? -20.759 2.686   -7.417  1   32.65  ? 338 GLU B CA  1 
ATOM   3804 C  C   . GLU B 2 168 ? -21.56  3.985   -7.37   1   33.07  ? 338 GLU B C   1 
ATOM   3805 O  O   . GLU B 2 168 ? -21.661 4.59    -6.304  1   34.69  ? 338 GLU B O   1 
ATOM   3806 C  CB  . GLU B 2 168 ? -19.362 2.937   -7.97   1   30.34  ? 338 GLU B CB  1 
ATOM   3807 C  CG  . GLU B 2 168 ? -18.309 2.181   -7.18   1   30.31  ? 338 GLU B CG  1 
ATOM   3808 C  CD  . GLU B 2 168 ? -16.897 2.334   -7.676  1   31.15  ? 338 GLU B CD  1 
ATOM   3809 O  OE1 . GLU B 2 168 ? -16.322 3.454   -7.62   1   32.63  ? 338 GLU B OE1 1 
ATOM   3810 O  OE2 . GLU B 2 168 ? -16.365 1.291   -8.077  1   30.71  ? 338 GLU B OE2 1 
ATOM   3811 N  N   . LEU B 2 169 ? -22.12  4.402   -8.519  1   29.71  ? 339 LEU B N   1 
ATOM   3812 C  CA  . LEU B 2 169 ? -22.882 5.643   -8.578  1   29.94  ? 339 LEU B CA  1 
ATOM   3813 C  C   . LEU B 2 169 ? -23.962 5.672   -7.495  1   28.59  ? 339 LEU B C   1 
ATOM   3814 O  O   . LEU B 2 169 ? -24.287 6.736   -6.974  1   28.79  ? 339 LEU B O   1 
ATOM   3815 C  CB  . LEU B 2 169 ? -23.496 5.867   -9.957  1   23.96  ? 339 LEU B CB  1 
ATOM   3816 C  CG  . LEU B 2 169 ? -22.514 6.231   -11.066 1   24.69  ? 339 LEU B CG  1 
ATOM   3817 C  CD1 . LEU B 2 169 ? -23.279 6.419   -12.38  1   24.98  ? 339 LEU B CD1 1 
ATOM   3818 C  CD2 . LEU B 2 169 ? -21.722 7.481   -10.722 1   23.1   ? 339 LEU B CD2 1 
ATOM   3819 N  N   . SER B 2 170 ? -24.538 4.505   -7.202  1   27.58  ? 340 SER B N   1 
ATOM   3820 C  CA  . SER B 2 170 ? -25.615 4.392   -6.231  1   29.32  ? 340 SER B CA  1 
ATOM   3821 C  C   . SER B 2 170 ? -25.121 4.75    -4.823  1   27.61  ? 340 SER B C   1 
ATOM   3822 O  O   . SER B 2 170 ? -25.903 5.24    -4.032  1   30.62  ? 340 SER B O   1 
ATOM   3823 C  CB  . SER B 2 170 ? -26.25  3.016   -6.259  1   26.77  ? 340 SER B CB  1 
ATOM   3824 O  OG  . SER B 2 170 ? -25.449 2.111   -5.519  1   30.96  ? 340 SER B OG  1 
ATOM   3825 N  N   . LEU B 2 171 ? -23.839 4.526   -4.524  1   25.2   ? 341 LEU B N   1 
ATOM   3826 C  CA  . LEU B 2 171 ? -23.302 4.791   -3.206  1   26.62  ? 341 LEU B CA  1 
ATOM   3827 C  C   . LEU B 2 171 ? -23.429 6.274   -2.873  1   28.06  ? 341 LEU B C   1 
ATOM   3828 O  O   . LEU B 2 171 ? -23.465 6.638   -1.692  1   25.42  ? 341 LEU B O   1 
ATOM   3829 C  CB  . LEU B 2 171 ? -21.824 4.404   -3.12   1   27.55  ? 341 LEU B CB  1 
ATOM   3830 C  CG  . LEU B 2 171 ? -21.457 2.937   -3.374  1   28.97  ? 341 LEU B CG  1 
ATOM   3831 C  CD1 . LEU B 2 171 ? -19.942 2.777   -3.33   1   25.31  ? 341 LEU B CD1 1 
ATOM   3832 C  CD2 . LEU B 2 171 ? -22.13  2.04    -2.353  1   25.8   ? 341 LEU B CD2 1 
ATOM   3833 N  N   . ILE B 2 172 ? -23.404 7.114   -3.921  1   29.68  ? 342 ILE B N   1 
ATOM   3834 C  CA  . ILE B 2 172 ? -23.223 8.554   -3.79   1   28.75  ? 342 ILE B CA  1 
ATOM   3835 C  C   . ILE B 2 172 ? -24.463 9.177   -3.162  1   29.1   ? 342 ILE B C   1 
ATOM   3836 O  O   . ILE B 2 172 ? -24.34  10.154  -2.407  1   33.45  ? 342 ILE B O   1 
ATOM   3837 C  CB  . ILE B 2 172 ? -22.845 9.215   -5.136  1   27.79  ? 342 ILE B CB  1 
ATOM   3838 C  CG1 . ILE B 2 172 ? -21.471 8.758   -5.609  1   27.54  ? 342 ILE B CG1 1 
ATOM   3839 C  CG2 . ILE B 2 172 ? -22.903 10.745  -5.06   1   25.63  ? 342 ILE B CG2 1 
ATOM   3840 C  CD1 . ILE B 2 172 ? -20.33  9.275   -4.753  1   27.7   ? 342 ILE B CD1 1 
ATOM   3841 N  N   . ASP B 2 173 ? -25.615 8.64    -3.57   1   28.32  ? 343 ASP B N   1 
ATOM   3842 C  CA  . ASP B 2 173 ? -26.909 9.273   -3.225  1   30.68  ? 343 ASP B CA  1 
ATOM   3843 C  C   . ASP B 2 173 ? -27.777 8.414   -2.318  1   31.39  ? 343 ASP B C   1 
ATOM   3844 O  O   . ASP B 2 173 ? -28.42  7.491   -2.818  1   37.3   ? 343 ASP B O   1 
ATOM   3845 C  CB  . ASP B 2 173 ? -27.635 9.636   -4.51   1   30.1   ? 343 ASP B CB  1 
ATOM   3846 C  CG  . ASP B 2 173 ? -26.818 10.44   -5.508  1   32.1   ? 343 ASP B CG  1 
ATOM   3847 O  OD1 . ASP B 2 173 ? -26.463 11.586  -5.182  1   27     ? 343 ASP B OD1 1 
ATOM   3848 O  OD2 . ASP B 2 173 ? -26.537 9.91    -6.599  1   34.77  ? 343 ASP B OD2 1 
ATOM   3849 N  N   . ALA B 2 174 ? -27.842 8.779   -1.046  1   31.15  ? 344 ALA B N   1 
ATOM   3850 C  CA  . ALA B 2 174 ? -28.682 8.067   -0.065  1   31.07  ? 344 ALA B CA  1 
ATOM   3851 C  C   . ALA B 2 174 ? -30.144 8.163   -0.491  1   31.32  ? 344 ALA B C   1 
ATOM   3852 O  O   . ALA B 2 174 ? -30.921 7.27    -0.135  1   30.66  ? 344 ALA B O   1 
ATOM   3853 C  CB  . ALA B 2 174 ? -28.436 8.69    1.272   1   34.47  ? 344 ALA B CB  1 
ATOM   3854 N  N   . ASP B 2 175 ? -30.513 9.232   -1.196  1   28.77  ? 345 ASP B N   1 
ATOM   3855 C  CA  . ASP B 2 175 ? -31.879 9.326   -1.766  1   29.49  ? 345 ASP B CA  1 
ATOM   3856 C  C   . ASP B 2 175 ? -31.739 9.204   -3.28   1   29.17  ? 345 ASP B C   1 
ATOM   3857 O  O   . ASP B 2 175 ? -31.27  10.157  -3.905  1   32.63  ? 345 ASP B O   1 
ATOM   3858 C  CB  . ASP B 2 175 ? -32.6   10.59   -1.336  1   28.68  ? 345 ASP B CB  1 
ATOM   3859 C  CG  . ASP B 2 175 ? -33.996 10.797  -1.901  1   29.61  ? 345 ASP B CG  1 
ATOM   3860 O  OD1 . ASP B 2 175 ? -34.672 9.795   -2.187  1   29.72  ? 345 ASP B OD1 1 
ATOM   3861 O  OD2 . ASP B 2 175 ? -34.398 11.965  -2.037  1   32.72  ? 345 ASP B OD2 1 
ATOM   3862 N  N   . PRO B 2 176 ? -32.113 8.062   -3.882  1   28.43  ? 346 PRO B N   1 
ATOM   3863 C  CA  . PRO B 2 176 ? -32.932 7.077   -3.185  1   27.04  ? 346 PRO B CA  1 
ATOM   3864 C  C   . PRO B 2 176 ? -32.386 5.707   -2.842  1   26.74  ? 346 PRO B C   1 
ATOM   3865 O  O   . PRO B 2 176 ? -33.18  4.846   -2.473  1   28.7   ? 346 PRO B O   1 
ATOM   3866 C  CB  . PRO B 2 176 ? -33.829 6.968   -4.412  1   23.89  ? 346 PRO B CB  1 
ATOM   3867 C  CG  . PRO B 2 176 ? -32.869 6.687   -5.531  1   23.73  ? 346 PRO B CG  1 
ATOM   3868 C  CD  . PRO B 2 176 ? -31.814 7.729   -5.26   1   24.91  ? 346 PRO B CD  1 
ATOM   3869 N  N   . TYR B 2 177 ? -31.076 5.516   -2.879  1   25.21  ? 347 TYR B N   1 
ATOM   3870 C  CA  . TYR B 2 177 ? -30.525 4.139   -2.8    1   30.39  ? 347 TYR B CA  1 
ATOM   3871 C  C   . TYR B 2 177 ? -30.496 3.561   -1.402  1   33.78  ? 347 TYR B C   1 
ATOM   3872 O  O   . TYR B 2 177 ? -30.309 2.346   -1.299  1   32.52  ? 347 TYR B O   1 
ATOM   3873 C  CB  . TYR B 2 177 ? -29.201 4.22    -3.562  1   29.21  ? 347 TYR B CB  1 
ATOM   3874 C  CG  . TYR B 2 177 ? -29.428 4.569   -5.023  1   30.55  ? 347 TYR B CG  1 
ATOM   3875 C  CD1 . TYR B 2 177 ? -30.212 3.759   -5.831  1   28.6   ? 347 TYR B CD1 1 
ATOM   3876 C  CD2 . TYR B 2 177 ? -28.888 5.72    -5.577  1   30.5   ? 347 TYR B CD2 1 
ATOM   3877 C  CE1 . TYR B 2 177 ? -30.439 4.074   -7.158  1   30.57  ? 347 TYR B CE1 1 
ATOM   3878 C  CE2 . TYR B 2 177 ? -29.104 6.045   -6.903  1   30.76  ? 347 TYR B CE2 1 
ATOM   3879 C  CZ  . TYR B 2 177 ? -29.884 5.221   -7.69   1   29.15  ? 347 TYR B CZ  1 
ATOM   3880 O  OH  . TYR B 2 177 ? -30.104 5.542   -8.989  1   26.28  ? 347 TYR B OH  1 
ATOM   3881 N  N   . LEU B 2 178 ? -30.708 4.366   -0.373  1   33.5   ? 348 LEU B N   1 
ATOM   3882 C  CA  . LEU B 2 178 ? -30.743 3.738   0.94    1   34.03  ? 348 LEU B CA  1 
ATOM   3883 C  C   . LEU B 2 178 ? -31.93  2.787   1.05    1   34.28  ? 348 LEU B C   1 
ATOM   3884 O  O   . LEU B 2 178 ? -31.906 1.883   1.881   1   40.41  ? 348 LEU B O   1 
ATOM   3885 C  CB  . LEU B 2 178 ? -30.79  4.75    2.077   1   35.45  ? 348 LEU B CB  1 
ATOM   3886 C  CG  . LEU B 2 178 ? -29.45  5.325   2.533   1   34.29  ? 348 LEU B CG  1 
ATOM   3887 C  CD1 . LEU B 2 178 ? -29.691 6.297   3.676   1   28.75  ? 348 LEU B CD1 1 
ATOM   3888 C  CD2 . LEU B 2 178 ? -28.492 4.214   2.926   1   32.2   ? 348 LEU B CD2 1 
ATOM   3889 N  N   . LYS B 2 179 ? -32.956 2.992   0.22    1   32.43  ? 349 LYS B N   1 
ATOM   3890 C  CA  . LYS B 2 179 ? -34.182 2.221   0.34    1   33.4   ? 349 LYS B CA  1 
ATOM   3891 C  C   . LYS B 2 179 ? -34.025 0.85    -0.317  1   35.85  ? 349 LYS B C   1 
ATOM   3892 O  O   . LYS B 2 179 ? -34.852 -0.025  -0.083  1   43.69  ? 349 LYS B O   1 
ATOM   3893 C  CB  . LYS B 2 179 ? -35.403 3.006   -0.143  1   35.94  ? 349 LYS B CB  1 
ATOM   3894 C  CG  . LYS B 2 179 ? -35.664 3.056   -1.644  1   41.58  ? 349 LYS B CG  1 
ATOM   3895 C  CD  . LYS B 2 179 ? -36.846 3.934   -2.08   1   44.02  ? 349 LYS B CD  1 
ATOM   3896 C  CE  . LYS B 2 179 ? -36.716 5.379   -1.672  1   45.82  ? 349 LYS B CE  1 
ATOM   3897 N  NZ  . LYS B 2 179 ? -37.643 6.27    -2.378  1   43.11  ? 349 LYS B NZ  1 
ATOM   3898 N  N   . TYR B 2 180 ? -32.957 0.646   -1.098  1   32.03  ? 350 TYR B N   1 
ATOM   3899 C  CA  . TYR B 2 180 ? -32.768 -0.627  -1.776  1   31.93  ? 350 TYR B CA  1 
ATOM   3900 C  C   . TYR B 2 180 ? -31.643 -1.442  -1.132  1   33.66  ? 350 TYR B C   1 
ATOM   3901 O  O   . TYR B 2 180 ? -30.625 -0.887  -0.725  1   37.24  ? 350 TYR B O   1 
ATOM   3902 C  CB  . TYR B 2 180 ? -32.501 -0.428  -3.269  1   31.92  ? 350 TYR B CB  1 
ATOM   3903 C  CG  . TYR B 2 180 ? -33.547 0.382   -4.019  1   32.03  ? 350 TYR B CG  1 
ATOM   3904 C  CD1 . TYR B 2 180 ? -34.835 -0.121  -4.232  1   27.87  ? 350 TYR B CD1 1 
ATOM   3905 C  CD2 . TYR B 2 180 ? -33.219 1.647   -4.516  1   27.39  ? 350 TYR B CD2 1 
ATOM   3906 C  CE1 . TYR B 2 180 ? -35.774 0.63    -4.921  1   28.44  ? 350 TYR B CE1 1 
ATOM   3907 C  CE2 . TYR B 2 180 ? -34.157 2.404   -5.186  1   26.36  ? 350 TYR B CE2 1 
ATOM   3908 C  CZ  . TYR B 2 180 ? -35.424 1.891   -5.393  1   27.5   ? 350 TYR B CZ  1 
ATOM   3909 O  OH  . TYR B 2 180 ? -36.277 2.685   -6.084  1   28.21  ? 350 TYR B OH  1 
ATOM   3910 N  N   . LEU B 2 181 ? -31.831 -2.773  -1.096  1   30.36  ? 351 LEU B N   1 
ATOM   3911 C  CA  . LEU B 2 181 ? -30.852 -3.722  -0.594  1   28.16  ? 351 LEU B CA  1 
ATOM   3912 C  C   . LEU B 2 181 ? -29.751 -3.887  -1.627  1   28.07  ? 351 LEU B C   1 
ATOM   3913 O  O   . LEU B 2 181 ? -29.977 -3.766  -2.823  1   29.4   ? 351 LEU B O   1 
ATOM   3914 C  CB  . LEU B 2 181 ? -31.522 -5.07   -0.315  1   28.14  ? 351 LEU B CB  1 
ATOM   3915 C  CG  . LEU B 2 181 ? -32.533 -5.1    0.839   1   25.2   ? 351 LEU B CG  1 
ATOM   3916 C  CD1 . LEU B 2 181 ? -33.305 -6.416  0.891   1   22.75  ? 351 LEU B CD1 1 
ATOM   3917 C  CD2 . LEU B 2 181 ? -31.849 -4.817  2.163   1   21.68  ? 351 LEU B CD2 1 
ATOM   3918 N  N   . PRO B 2 182 ? -28.508 -4.163  -1.198  1   28.45  ? 352 PRO B N   1 
ATOM   3919 C  CA  . PRO B 2 182 ? -27.411 -4.412  -2.136  1   27.82  ? 352 PRO B CA  1 
ATOM   3920 C  C   . PRO B 2 182 ? -27.81  -5.333  -3.272  1   27.01  ? 352 PRO B C   1 
ATOM   3921 O  O   . PRO B 2 182 ? -27.454 -5.082  -4.412  1   29.23  ? 352 PRO B O   1 
ATOM   3922 C  CB  . PRO B 2 182 ? -26.383 -5.079  -1.243  1   26.4   ? 352 PRO B CB  1 
ATOM   3923 C  CG  . PRO B 2 182 ? -26.588 -4.348  0.06    1   26.59  ? 352 PRO B CG  1 
ATOM   3924 C  CD  . PRO B 2 182 ? -28.082 -4.147  0.205   1   24.8   ? 352 PRO B CD  1 
ATOM   3925 N  N   . SER B 2 183 ? -28.536 -6.394  -2.934  1   25.18  ? 353 SER B N   1 
ATOM   3926 C  CA  . SER B 2 183 ? -28.824 -7.456  -3.878  1   24.75  ? 353 SER B CA  1 
ATOM   3927 C  C   . SER B 2 183 ? -29.694 -6.919  -5.005  1   27.33  ? 353 SER B C   1 
ATOM   3928 O  O   . SER B 2 183 ? -29.558 -7.376  -6.14   1   26.58  ? 353 SER B O   1 
ATOM   3929 C  CB  . SER B 2 183 ? -29.468 -8.65   -3.209  1   23.88  ? 353 SER B CB  1 
ATOM   3930 O  OG  . SER B 2 183 ? -30.752 -8.343  -2.704  1   24.95  ? 353 SER B OG  1 
ATOM   3931 N  N   . VAL B 2 184 ? -30.565 -5.95   -4.672  1   27.28  ? 354 VAL B N   1 
ATOM   3932 C  CA  . VAL B 2 184 ? -31.483 -5.354  -5.628  1   27.55  ? 354 VAL B CA  1 
ATOM   3933 C  C   . VAL B 2 184 ? -30.776 -4.327  -6.519  1   29.26  ? 354 VAL B C   1 
ATOM   3934 O  O   . VAL B 2 184 ? -31.025 -4.273  -7.723  1   28.88  ? 354 VAL B O   1 
ATOM   3935 C  CB  . VAL B 2 184 ? -32.701 -4.761  -4.898  1   28.13  ? 354 VAL B CB  1 
ATOM   3936 C  CG1 . VAL B 2 184 ? -33.5   -3.796  -5.786  1   26     ? 354 VAL B CG1 1 
ATOM   3937 C  CG2 . VAL B 2 184 ? -33.578 -5.877  -4.316  1   24.81  ? 354 VAL B CG2 1 
ATOM   3938 N  N   . ILE B 2 185 ? -29.902 -3.492  -5.944  1   29.55  ? 355 ILE B N   1 
ATOM   3939 C  CA  . ILE B 2 185 ? -29.212 -2.496  -6.754  1   30.61  ? 355 ILE B CA  1 
ATOM   3940 C  C   . ILE B 2 185 ? -28.262 -3.208  -7.709  1   30.99  ? 355 ILE B C   1 
ATOM   3941 O  O   . ILE B 2 185 ? -28.089 -2.801  -8.85   1   31.36  ? 355 ILE B O   1 
ATOM   3942 C  CB  . ILE B 2 185 ? -28.422 -1.522  -5.871  1   29.4   ? 355 ILE B CB  1 
ATOM   3943 C  CG1 . ILE B 2 185 ? -29.363 -0.731  -4.968  1   28.76  ? 355 ILE B CG1 1 
ATOM   3944 C  CG2 . ILE B 2 185 ? -27.53  -0.622  -6.73   1   23.31  ? 355 ILE B CG2 1 
ATOM   3945 C  CD1 . ILE B 2 185 ? -28.61  0.068   -3.927  1   27.91  ? 355 ILE B CD1 1 
ATOM   3946 N  N   . ALA B 2 186 ? -27.616 -4.246  -7.186  1   29.12  ? 356 ALA B N   1 
ATOM   3947 C  CA  . ALA B 2 186 ? -26.757 -5.104  -7.965  1   27.22  ? 356 ALA B CA  1 
ATOM   3948 C  C   . ALA B 2 186 ? -27.541 -5.662  -9.147  1   28.21  ? 356 ALA B C   1 
ATOM   3949 O  O   . ALA B 2 186 ? -27.044 -5.686  -10.263 1   31.95  ? 356 ALA B O   1 
ATOM   3950 C  CB  . ALA B 2 186 ? -26.215 -6.194  -7.08   1   24.98  ? 356 ALA B CB  1 
ATOM   3951 N  N   . ALA B 2 187 ? -28.782 -6.072  -8.909  1   26.5   ? 357 ALA B N   1 
ATOM   3952 C  CA  . ALA B 2 187 ? -29.576 -6.665  -9.968  1   26.96  ? 357 ALA B CA  1 
ATOM   3953 C  C   . ALA B 2 187 ? -29.884 -5.578  -10.996 1   27.01  ? 357 ALA B C   1 
ATOM   3954 O  O   . ALA B 2 187 ? -29.706 -5.795  -12.201 1   26.23  ? 357 ALA B O   1 
ATOM   3955 C  CB  . ALA B 2 187 ? -30.835 -7.312  -9.389  1   24.61  ? 357 ALA B CB  1 
ATOM   3956 N  N   . ALA B 2 188 ? -30.306 -4.404  -10.495 1   23.84  ? 358 ALA B N   1 
ATOM   3957 C  CA  . ALA B 2 188 ? -30.664 -3.294  -11.367 1   24.04  ? 358 ALA B CA  1 
ATOM   3958 C  C   . ALA B 2 188 ? -29.455 -2.947  -12.223 1   24.75  ? 358 ALA B C   1 
ATOM   3959 O  O   . ALA B 2 188 ? -29.553 -2.745  -13.433 1   23.7   ? 358 ALA B O   1 
ATOM   3960 C  CB  . ALA B 2 188 ? -31.113 -2.093  -10.558 1   23.55  ? 358 ALA B CB  1 
ATOM   3961 N  N   . ALA B 2 189 ? -28.306 -2.924  -11.548 1   26.32  ? 359 ALA B N   1 
ATOM   3962 C  CA  . ALA B 2 189 ? -27.057 -2.54   -12.168 1   28.35  ? 359 ALA B CA  1 
ATOM   3963 C  C   . ALA B 2 189 ? -26.709 -3.542  -13.264 1   29.58  ? 359 ALA B C   1 
ATOM   3964 O  O   . ALA B 2 189 ? -26.342 -3.134  -14.373 1   29.68  ? 359 ALA B O   1 
ATOM   3965 C  CB  . ALA B 2 189 ? -25.985 -2.439  -11.108 1   26.58  ? 359 ALA B CB  1 
ATOM   3966 N  N   . PHE B 2 190 ? -26.843 -4.838  -12.935 1   24.95  ? 360 PHE B N   1 
ATOM   3967 C  CA  . PHE B 2 190 ? -26.471 -5.878  -13.869 1   24.3   ? 360 PHE B CA  1 
ATOM   3968 C  C   . PHE B 2 190 ? -27.343 -5.783  -15.115 1   25.48  ? 360 PHE B C   1 
ATOM   3969 O  O   . PHE B 2 190 ? -26.818 -5.855  -16.222 1   27.5   ? 360 PHE B O   1 
ATOM   3970 C  CB  . PHE B 2 190 ? -26.477 -7.276  -13.263 1   22.44  ? 360 PHE B CB  1 
ATOM   3971 C  CG  . PHE B 2 190 ? -26.054 -8.343  -14.256 1   23.92  ? 360 PHE B CG  1 
ATOM   3972 C  CD1 . PHE B 2 190 ? -24.759 -8.34   -14.788 1   23.2   ? 360 PHE B CD1 1 
ATOM   3973 C  CD2 . PHE B 2 190 ? -26.945 -9.352  -14.647 1   24.46  ? 360 PHE B CD2 1 
ATOM   3974 C  CE1 . PHE B 2 190 ? -24.359 -9.336  -15.676 1   23.19  ? 360 PHE B CE1 1 
ATOM   3975 C  CE2 . PHE B 2 190 ? -26.549 -10.344 -15.544 1   22.5   ? 360 PHE B CE2 1 
ATOM   3976 C  CZ  . PHE B 2 190 ? -25.262 -10.333 -16.055 1   23.28  ? 360 PHE B CZ  1 
ATOM   3977 N  N   . HIS B 2 191 ? -28.658 -5.596  -14.929 1   25.34  ? 361 HIS B N   1 
ATOM   3978 C  CA  . HIS B 2 191 ? -29.59  -5.633  -16.05  1   24.38  ? 361 HIS B CA  1 
ATOM   3979 C  C   . HIS B 2 191 ? -29.345 -4.436  -16.952 1   25.19  ? 361 HIS B C   1 
ATOM   3980 O  O   . HIS B 2 191 ? -29.434 -4.539  -18.175 1   23.38  ? 361 HIS B O   1 
ATOM   3981 C  CB  . HIS B 2 191 ? -31.056 -5.579  -15.603 1   21.68  ? 361 HIS B CB  1 
ATOM   3982 C  CG  . HIS B 2 191 ? -31.977 -5.226  -16.721 1   20.14  ? 361 HIS B CG  1 
ATOM   3983 N  ND1 . HIS B 2 191 ? -32.27  -6.121  -17.727 1   19.11  ? 361 HIS B ND1 1 
ATOM   3984 C  CD2 . HIS B 2 191 ? -32.614 -4.073  -17.047 1   19.74  ? 361 HIS B CD2 1 
ATOM   3985 C  CE1 . HIS B 2 191 ? -33.086 -5.544  -18.599 1   19.82  ? 361 HIS B CE1 1 
ATOM   3986 N  NE2 . HIS B 2 191 ? -33.299 -4.296  -18.215 1   19.54  ? 361 HIS B NE2 1 
ATOM   3987 N  N   . LEU B 2 192 ? -29.085 -3.289  -16.313 1   26.25  ? 362 LEU B N   1 
ATOM   3988 C  CA  . LEU B 2 192 ? -28.907 -2.05   -17.048 1   24.7   ? 362 LEU B CA  1 
ATOM   3989 C  C   . LEU B 2 192 ? -27.588 -2.111  -17.822 1   25.96  ? 362 LEU B C   1 
ATOM   3990 O  O   . LEU B 2 192 ? -27.51  -1.67   -18.973 1   25.5   ? 362 LEU B O   1 
ATOM   3991 C  CB  . LEU B 2 192 ? -28.967 -0.913  -16.037 1   22.91  ? 362 LEU B CB  1 
ATOM   3992 C  CG  . LEU B 2 192 ? -28.973 0.492   -16.638 1   23.63  ? 362 LEU B CG  1 
ATOM   3993 C  CD1 . LEU B 2 192 ? -29.978 0.619   -17.786 1   22.38  ? 362 LEU B CD1 1 
ATOM   3994 C  CD2 . LEU B 2 192 ? -29.238 1.495   -15.529 1   22.38  ? 362 LEU B CD2 1 
ATOM   3995 N  N   . ALA B 2 193 ? -26.567 -2.712  -17.198 1   24.78  ? 363 ALA B N   1 
ATOM   3996 C  CA  . ALA B 2 193 ? -25.291 -2.85   -17.864 1   25.83  ? 363 ALA B CA  1 
ATOM   3997 C  C   . ALA B 2 193 ? -25.5   -3.738  -19.086 1   27.69  ? 363 ALA B C   1 
ATOM   3998 O  O   . ALA B 2 193 ? -25.185 -3.352  -20.219 1   29.82  ? 363 ALA B O   1 
ATOM   3999 C  CB  . ALA B 2 193 ? -24.233 -3.375  -16.914 1   23.99  ? 363 ALA B CB  1 
ATOM   4000 N  N   . LEU B 2 194 ? -26.083 -4.905  -18.826 1   29     ? 364 LEU B N   1 
ATOM   4001 C  CA  . LEU B 2 194 ? -26.338 -5.928  -19.829 1   31.57  ? 364 LEU B CA  1 
ATOM   4002 C  C   . LEU B 2 194 ? -27.064 -5.329  -21.029 1   27.69  ? 364 LEU B C   1 
ATOM   4003 O  O   . LEU B 2 194 ? -26.62  -5.482  -22.165 1   30.32  ? 364 LEU B O   1 
ATOM   4004 C  CB  . LEU B 2 194 ? -27.185 -7.003  -19.147 1   34.16  ? 364 LEU B CB  1 
ATOM   4005 C  CG  . LEU B 2 194 ? -27.315 -8.327  -19.895 1   36.05  ? 364 LEU B CG  1 
ATOM   4006 C  CD1 . LEU B 2 194 ? -25.932 -8.853  -20.217 1   35.45  ? 364 LEU B CD1 1 
ATOM   4007 C  CD2 . LEU B 2 194 ? -28.069 -9.286  -18.986 1   40.73  ? 364 LEU B CD2 1 
ATOM   4008 N  N   . TYR B 2 195 ? -28.151 -4.614  -20.742 1   25.3   ? 365 TYR B N   1 
ATOM   4009 C  CA  . TYR B 2 195 ? -29.045 -4.071  -21.742 1   24.83  ? 365 TYR B CA  1 
ATOM   4010 C  C   . TYR B 2 195 ? -28.351 -2.99   -22.569 1   25.59  ? 365 TYR B C   1 
ATOM   4011 O  O   . TYR B 2 195 ? -28.526 -2.908  -23.769 1   25.05  ? 365 TYR B O   1 
ATOM   4012 C  CB  . TYR B 2 195 ? -30.268 -3.498  -21.03  1   23.58  ? 365 TYR B CB  1 
ATOM   4013 C  CG  . TYR B 2 195 ? -31.275 -2.936  -22.018 1   25.28  ? 365 TYR B CG  1 
ATOM   4014 C  CD1 . TYR B 2 195 ? -32.036 -3.787  -22.811 1   25.02  ? 365 TYR B CD1 1 
ATOM   4015 C  CD2 . TYR B 2 195 ? -31.447 -1.57   -22.179 1   24.94  ? 365 TYR B CD2 1 
ATOM   4016 C  CE1 . TYR B 2 195 ? -32.973 -3.307  -23.704 1   24.79  ? 365 TYR B CE1 1 
ATOM   4017 C  CE2 . TYR B 2 195 ? -32.39  -1.078  -23.066 1   27.08  ? 365 TYR B CE2 1 
ATOM   4018 C  CZ  . TYR B 2 195 ? -33.152 -1.943  -23.839 1   28.32  ? 365 TYR B CZ  1 
ATOM   4019 O  OH  . TYR B 2 195 ? -34.089 -1.463  -24.732 1   32.68  ? 365 TYR B OH  1 
ATOM   4020 N  N   . THR B 2 196 ? -27.604 -2.117  -21.903 1   26.93  ? 366 THR B N   1 
ATOM   4021 C  CA  . THR B 2 196 ? -26.869 -1.049  -22.561 1   26.73  ? 366 THR B CA  1 
ATOM   4022 C  C   . THR B 2 196 ? -25.903 -1.662  -23.569 1   27.33  ? 366 THR B C   1 
ATOM   4023 O  O   . THR B 2 196 ? -25.853 -1.248  -24.719 1   32.02  ? 366 THR B O   1 
ATOM   4024 C  CB  . THR B 2 196 ? -26.134 -0.2    -21.513 1   27.12  ? 366 THR B CB  1 
ATOM   4025 O  OG1 . THR B 2 196 ? -27.108 0.324   -20.605 1   25.12  ? 366 THR B OG1 1 
ATOM   4026 C  CG2 . THR B 2 196 ? -25.286 0.91    -22.12  1   21     ? 366 THR B CG2 1 
ATOM   4027 N  N   . VAL B 2 197 ? -25.144 -2.661  -23.132 1   28.5   ? 367 VAL B N   1 
ATOM   4028 C  CA  . VAL B 2 197 ? -23.997 -3.124  -23.897 1   27.86  ? 367 VAL B CA  1 
ATOM   4029 C  C   . VAL B 2 197 ? -24.457 -4.091  -24.988 1   26.35  ? 367 VAL B C   1 
ATOM   4030 O  O   . VAL B 2 197 ? -24.003 -3.962  -26.123 1   26.88  ? 367 VAL B O   1 
ATOM   4031 C  CB  . VAL B 2 197 ? -22.893 -3.743  -23.009 1   24.55  ? 367 VAL B CB  1 
ATOM   4032 C  CG1 . VAL B 2 197 ? -21.867 -4.51   -23.836 1   21.25  ? 367 VAL B CG1 1 
ATOM   4033 C  CG2 . VAL B 2 197 ? -22.212 -2.684  -22.162 1   22.79  ? 367 VAL B CG2 1 
ATOM   4034 N  N   . THR B 2 198 ? -25.355 -5.031  -24.632 1   24.27  ? 368 THR B N   1 
ATOM   4035 C  CA  . THR B 2 198 ? -25.703 -6.167  -25.487 1   22.63  ? 368 THR B CA  1 
ATOM   4036 C  C   . THR B 2 198 ? -27.156 -6.137  -25.952 1   20.78  ? 368 THR B C   1 
ATOM   4037 O  O   . THR B 2 198 ? -27.555 -6.995  -26.729 1   19.74  ? 368 THR B O   1 
ATOM   4038 C  CB  . THR B 2 198 ? -25.482 -7.5    -24.774 1   21.96  ? 368 THR B CB  1 
ATOM   4039 O  OG1 . THR B 2 198 ? -26.505 -7.562  -23.781 1   23.35  ? 368 THR B OG1 1 
ATOM   4040 C  CG2 . THR B 2 198 ? -24.09  -7.628  -24.196 1   21.89  ? 368 THR B CG2 1 
ATOM   4041 N  N   . GLY B 2 199 ? -27.964 -5.237  -25.396 1   21.39  ? 369 GLY B N   1 
ATOM   4042 C  CA  . GLY B 2 199 ? -29.398 -5.258  -25.626 1   23.61  ? 369 GLY B CA  1 
ATOM   4043 C  C   . GLY B 2 199 ? -30.117 -6.409  -24.912 1   28.83  ? 369 GLY B C   1 
ATOM   4044 O  O   . GLY B 2 199 ? -31.301 -6.609  -25.143 1   33.03  ? 369 GLY B O   1 
ATOM   4045 N  N   . GLN B 2 200 ? -29.452 -7.173  -24.041 1   29     ? 370 GLN B N   1 
ATOM   4046 C  CA  . GLN B 2 200 ? -30.157 -8.301  -23.456 1   33.5   ? 370 GLN B CA  1 
ATOM   4047 C  C   . GLN B 2 200 ? -30.673 -7.936  -22.07  1   34.51  ? 370 GLN B C   1 
ATOM   4048 O  O   . GLN B 2 200 ? -30.276 -6.903  -21.519 1   33.49  ? 370 GLN B O   1 
ATOM   4049 C  CB  . GLN B 2 200 ? -29.228 -9.497  -23.324 1   41.48  ? 370 GLN B CB  1 
ATOM   4050 C  CG  . GLN B 2 200 ? -28.845 -10.129 -24.651 1   46.66  ? 370 GLN B CG  1 
ATOM   4051 C  CD  . GLN B 2 200 ? -27.793 -11.182 -24.415 1   54.45  ? 370 GLN B CD  1 
ATOM   4052 O  OE1 . GLN B 2 200 ? -28.025 -12.363 -24.68  1   69.59  ? 370 GLN B OE1 1 
ATOM   4053 N  NE2 . GLN B 2 200 ? -26.656 -10.773 -23.86  1   49.49  ? 370 GLN B NE2 1 
ATOM   4054 N  N   . SER B 2 201 ? -31.51  -8.823  -21.501 1   33.67  ? 371 SER B N   1 
ATOM   4055 C  CA  . SER B 2 201 ? -32.156 -8.548  -20.222 1   32.46  ? 371 SER B CA  1 
ATOM   4056 C  C   . SER B 2 201 ? -31.734 -9.523  -19.13  1   31.58  ? 371 SER B C   1 
ATOM   4057 O  O   . SER B 2 201 ? -31.141 -10.567 -19.391 1   31.23  ? 371 SER B O   1 
ATOM   4058 C  CB  . SER B 2 201 ? -33.645 -8.55   -20.349 1   31.17  ? 371 SER B CB  1 
ATOM   4059 O  OG  . SER B 2 201 ? -34.01  -7.572  -21.306 1   37.56  ? 371 SER B OG  1 
ATOM   4060 N  N   . TRP B 2 202 ? -32.097 -9.14   -17.899 1   32.7   ? 372 TRP B N   1 
ATOM   4061 C  CA  . TRP B 2 202 ? -32.07  -9.96   -16.703 1   29.43  ? 372 TRP B CA  1 
ATOM   4062 C  C   . TRP B 2 202 ? -32.426 -11.386 -17.09  1   30.23  ? 372 TRP B C   1 
ATOM   4063 O  O   . TRP B 2 202 ? -33.541 -11.636 -17.546 1   30.56  ? 372 TRP B O   1 
ATOM   4064 C  CB  . TRP B 2 202 ? -33.093 -9.4    -15.707 1   27.83  ? 372 TRP B CB  1 
ATOM   4065 C  CG  . TRP B 2 202 ? -33.072 -10.016 -14.328 1   27.48  ? 372 TRP B CG  1 
ATOM   4066 C  CD1 . TRP B 2 202 ? -34.114 -10.679 -13.752 1   27.52  ? 372 TRP B CD1 1 
ATOM   4067 C  CD2 . TRP B 2 202 ? -32     -10.028 -13.358 1   24.86  ? 372 TRP B CD2 1 
ATOM   4068 N  NE1 . TRP B 2 202 ? -33.784 -11.073 -12.48  1   26.99  ? 372 TRP B NE1 1 
ATOM   4069 C  CE2 . TRP B 2 202 ? -32.499 -10.693 -12.211 1   26.4   ? 372 TRP B CE2 1 
ATOM   4070 C  CE3 . TRP B 2 202 ? -30.691 -9.53   -13.327 1   25.09  ? 372 TRP B CE3 1 
ATOM   4071 C  CZ2 . TRP B 2 202 ? -31.73  -10.896 -11.064 1   26.18  ? 372 TRP B CZ2 1 
ATOM   4072 C  CZ3 . TRP B 2 202 ? -29.933 -9.696  -12.183 1   26.09  ? 372 TRP B CZ3 1 
ATOM   4073 C  CH2 . TRP B 2 202 ? -30.452 -10.368 -11.071 1   28.01  ? 372 TRP B CH2 1 
ATOM   4074 N  N   . PRO B 2 203 ? -31.469 -12.332 -16.98  1   27.88  ? 373 PRO B N   1 
ATOM   4075 C  CA  . PRO B 2 203 ? -31.703 -13.724 -17.375 1   29.07  ? 373 PRO B CA  1 
ATOM   4076 C  C   . PRO B 2 203 ? -32.591 -14.562 -16.456 1   27.91  ? 373 PRO B C   1 
ATOM   4077 O  O   . PRO B 2 203 ? -32.563 -14.407 -15.233 1   29.44  ? 373 PRO B O   1 
ATOM   4078 C  CB  . PRO B 2 203 ? -30.277 -14.306 -17.452 1   27.47  ? 373 PRO B CB  1 
ATOM   4079 C  CG  . PRO B 2 203 ? -29.481 -13.465 -16.483 1   27.93  ? 373 PRO B CG  1 
ATOM   4080 C  CD  . PRO B 2 203 ? -30.095 -12.08  -16.532 1   26.23  ? 373 PRO B CD  1 
ATOM   4081 N  N   . GLU B 2 204 ? -33.336 -15.481 -17.078 1   26.62  ? 374 GLU B N   1 
ATOM   4082 C  CA  . GLU B 2 204 ? -34.145 -16.473 -16.388 1   30.29  ? 374 GLU B CA  1 
ATOM   4083 C  C   . GLU B 2 204 ? -33.353 -17.046 -15.207 1   30.67  ? 374 GLU B C   1 
ATOM   4084 O  O   . GLU B 2 204 ? -33.859 -17.12  -14.095 1   29.5   ? 374 GLU B O   1 
ATOM   4085 C  CB  . GLU B 2 204 ? -34.587 -17.545 -17.392 1   32.84  ? 374 GLU B CB  1 
ATOM   4086 C  CG  . GLU B 2 204 ? -34.782 -18.941 -16.791 1   38.63  ? 374 GLU B CG  1 
ATOM   4087 C  CD  . GLU B 2 204 ? -36.003 -19.037 -15.892 1   46.19  ? 374 GLU B CD  1 
ATOM   4088 O  OE1 . GLU B 2 204 ? -36.685 -17.998 -15.707 1   54.39  ? 374 GLU B OE1 1 
ATOM   4089 O  OE2 . GLU B 2 204 ? -36.295 -20.14  -15.397 1   47.75  ? 374 GLU B OE2 1 
ATOM   4090 N  N   . SER B 2 205 ? -32.098 -17.422 -15.47  1   27.25  ? 375 SER B N   1 
ATOM   4091 C  CA  . SER B 2 205 ? -31.281 -18.144 -14.521 1   26.08  ? 375 SER B CA  1 
ATOM   4092 C  C   . SER B 2 205 ? -31.082 -17.335 -13.231 1   25.65  ? 375 SER B C   1 
ATOM   4093 O  O   . SER B 2 205 ? -30.96  -17.931 -12.16  1   24.29  ? 375 SER B O   1 
ATOM   4094 C  CB  . SER B 2 205 ? -29.978 -18.571 -15.17  1   25.96  ? 375 SER B CB  1 
ATOM   4095 O  OG  . SER B 2 205 ? -29.004 -17.534 -15.165 1   31.74  ? 375 SER B OG  1 
ATOM   4096 N  N   . LEU B 2 206 ? -31.08  -15.996 -13.319 1   24.33  ? 376 LEU B N   1 
ATOM   4097 C  CA  . LEU B 2 206 ? -30.948 -15.157 -12.133 1   25.1   ? 376 LEU B CA  1 
ATOM   4098 C  C   . LEU B 2 206 ? -32.317 -14.932 -11.478 1   25.29  ? 376 LEU B C   1 
ATOM   4099 O  O   . LEU B 2 206 ? -32.419 -14.647 -10.277 1   21.77  ? 376 LEU B O   1 
ATOM   4100 C  CB  . LEU B 2 206 ? -30.246 -13.846 -12.465 1   22.89  ? 376 LEU B CB  1 
ATOM   4101 C  CG  . LEU B 2 206 ? -28.721 -13.942 -12.585 1   25.72  ? 376 LEU B CG  1 
ATOM   4102 C  CD1 . LEU B 2 206 ? -28.142 -12.639 -13.119 1   26.63  ? 376 LEU B CD1 1 
ATOM   4103 C  CD2 . LEU B 2 206 ? -28.048 -14.279 -11.258 1   24.63  ? 376 LEU B CD2 1 
ATOM   4104 N  N   . VAL B 2 207 ? -33.371 -15.092 -12.283 1   22.39  ? 377 VAL B N   1 
ATOM   4105 C  CA  . VAL B 2 207 ? -34.699 -15.167 -11.709 1   24.33  ? 377 VAL B CA  1 
ATOM   4106 C  C   . VAL B 2 207 ? -34.793 -16.402 -10.802 1   24.97  ? 377 VAL B C   1 
ATOM   4107 O  O   . VAL B 2 207 ? -35.401 -16.339 -9.744  1   27.14  ? 377 VAL B O   1 
ATOM   4108 C  CB  . VAL B 2 207 ? -35.769 -15.145 -12.817 1   22.61  ? 377 VAL B CB  1 
ATOM   4109 C  CG1 . VAL B 2 207 ? -37.17  -15.396 -12.281 1   19     ? 377 VAL B CG1 1 
ATOM   4110 C  CG2 . VAL B 2 207 ? -35.721 -13.838 -13.596 1   22.66  ? 377 VAL B CG2 1 
ATOM   4111 N  N   . GLN B 2 208 ? -34.15  -17.502 -11.191 1   23.82  ? 378 GLN B N   1 
ATOM   4112 C  CA  . GLN B 2 208 ? -34.158 -18.736 -10.43  1   25.69  ? 378 GLN B CA  1 
ATOM   4113 C  C   . GLN B 2 208 ? -33.332 -18.577 -9.153  1   26.67  ? 378 GLN B C   1 
ATOM   4114 O  O   . GLN B 2 208 ? -33.729 -19.032 -8.087  1   26.8   ? 378 GLN B O   1 
ATOM   4115 C  CB  . GLN B 2 208 ? -33.537 -19.87  -11.247 1   25.82  ? 378 GLN B CB  1 
ATOM   4116 C  CG  . GLN B 2 208 ? -34.361 -20.341 -12.433 1   26.63  ? 378 GLN B CG  1 
ATOM   4117 C  CD  . GLN B 2 208 ? -35.593 -21.083 -11.972 1   32.58  ? 378 GLN B CD  1 
ATOM   4118 O  OE1 . GLN B 2 208 ? -36.619 -21.106 -12.664 1   35.95  ? 378 GLN B OE1 1 
ATOM   4119 N  NE2 . GLN B 2 208 ? -35.524 -21.628 -10.761 1   32.76  ? 378 GLN B NE2 1 
ATOM   4120 N  N   . LYS B 2 209 ? -32.163 -17.954 -9.29   1   25.97  ? 379 LYS B N   1 
ATOM   4121 C  CA  . LYS B 2 209 ? -31.224 -17.794 -8.195  1   26.84  ? 379 LYS B CA  1 
ATOM   4122 C  C   . LYS B 2 209 ? -31.811 -16.848 -7.145  1   28.24  ? 379 LYS B C   1 
ATOM   4123 O  O   . LYS B 2 209 ? -31.728 -17.134 -5.949  1   29.8   ? 379 LYS B O   1 
ATOM   4124 C  CB  . LYS B 2 209 ? -29.918 -17.208 -8.753  1   27.24  ? 379 LYS B CB  1 
ATOM   4125 C  CG  . LYS B 2 209 ? -28.735 -17.258 -7.81   1   28.64  ? 379 LYS B CG  1 
ATOM   4126 C  CD  . LYS B 2 209 ? -27.607 -16.327 -8.232  1   30.96  ? 379 LYS B CD  1 
ATOM   4127 C  CE  . LYS B 2 209 ? -26.525 -16.272 -7.181  1   32.97  ? 379 LYS B CE  1 
ATOM   4128 N  NZ  . LYS B 2 209 ? -26.034 -17.609 -6.822  1   35.57  ? 379 LYS B NZ  1 
ATOM   4129 N  N   . THR B 2 210 ? -32.4   -15.733 -7.605  1   24.71  ? 380 THR B N   1 
ATOM   4130 C  CA  . THR B 2 210 ? -32.59  -14.559 -6.767  1   26.52  ? 380 THR B CA  1 
ATOM   4131 C  C   . THR B 2 210 ? -34.04  -14.456 -6.337  1   27.84  ? 380 THR B C   1 
ATOM   4132 O  O   . THR B 2 210 ? -34.297 -13.866 -5.284  1   35.27  ? 380 THR B O   1 
ATOM   4133 C  CB  . THR B 2 210 ? -32.219 -13.236 -7.461  1   28.02  ? 380 THR B CB  1 
ATOM   4134 O  OG1 . THR B 2 210 ? -33.159 -12.913 -8.496  1   26.18  ? 380 THR B OG1 1 
ATOM   4135 C  CG2 . THR B 2 210 ? -30.782 -13.214 -7.939  1   22.37  ? 380 THR B CG2 1 
ATOM   4136 N  N   . GLY B 2 211 ? -34.957 -14.903 -7.208  1   24.42  ? 381 GLY B N   1 
ATOM   4137 C  CA  . GLY B 2 211 ? -36.381 -14.656 -7.042  1   23.01  ? 381 GLY B CA  1 
ATOM   4138 C  C   . GLY B 2 211 ? -36.817 -13.297 -7.601  1   23.83  ? 381 GLY B C   1 
ATOM   4139 O  O   . GLY B 2 211 ? -38.006 -12.978 -7.599  1   23.22  ? 381 GLY B O   1 
ATOM   4140 N  N   . TYR B 2 212 ? -35.866 -12.489 -8.081  1   23.14  ? 382 TYR B N   1 
ATOM   4141 C  CA  . TYR B 2 212 ? -36.232 -11.181 -8.593  1   23.1   ? 382 TYR B CA  1 
ATOM   4142 C  C   . TYR B 2 212 ? -36.552 -11.292 -10.08  1   24.45  ? 382 TYR B C   1 
ATOM   4143 O  O   . TYR B 2 212 ? -35.946 -12.086 -10.804 1   24.65  ? 382 TYR B O   1 
ATOM   4144 C  CB  . TYR B 2 212 ? -35.068 -10.207 -8.421  1   25.69  ? 382 TYR B CB  1 
ATOM   4145 C  CG  . TYR B 2 212 ? -34.545 -9.964  -7.012  1   27.1   ? 382 TYR B CG  1 
ATOM   4146 C  CD1 . TYR B 2 212 ? -35.374 -10.062 -5.899  1   25.01  ? 382 TYR B CD1 1 
ATOM   4147 C  CD2 . TYR B 2 212 ? -33.212 -9.619  -6.81   1   24.96  ? 382 TYR B CD2 1 
ATOM   4148 C  CE1 . TYR B 2 212 ? -34.874 -9.836  -4.63   1   25.66  ? 382 TYR B CE1 1 
ATOM   4149 C  CE2 . TYR B 2 212 ? -32.712 -9.373  -5.542  1   25.12  ? 382 TYR B CE2 1 
ATOM   4150 C  CZ  . TYR B 2 212 ? -33.545 -9.48   -4.445  1   26.03  ? 382 TYR B CZ  1 
ATOM   4151 O  OH  . TYR B 2 212 ? -33.016 -9.236  -3.203  1   24.65  ? 382 TYR B OH  1 
ATOM   4152 N  N   . THR B 2 213 ? -37.512 -10.48  -10.524 1   26.51  ? 383 THR B N   1 
ATOM   4153 C  CA  . THR B 2 213 ? -37.865 -10.308 -11.931 1   29.64  ? 383 THR B CA  1 
ATOM   4154 C  C   . THR B 2 213 ? -37.733 -8.83   -12.283 1   34.73  ? 383 THR B C   1 
ATOM   4155 O  O   . THR B 2 213 ? -37.616 -7.985  -11.386 1   40.69  ? 383 THR B O   1 
ATOM   4156 C  CB  . THR B 2 213 ? -39.321 -10.718 -12.17  1   29.47  ? 383 THR B CB  1 
ATOM   4157 O  OG1 . THR B 2 213 ? -40.18  -9.716  -11.605 1   30.36  ? 383 THR B OG1 1 
ATOM   4158 C  CG2 . THR B 2 213 ? -39.641 -12.093 -11.612 1   26.01  ? 383 THR B CG2 1 
ATOM   4159 N  N   . LEU B 2 214 ? -37.846 -8.52   -13.579 1   30.98  ? 384 LEU B N   1 
ATOM   4160 C  CA  . LEU B 2 214 ? -37.899 -7.133  -14.006 1   29.48  ? 384 LEU B CA  1 
ATOM   4161 C  C   . LEU B 2 214 ? -39.033 -6.41   -13.298 1   31.68  ? 384 LEU B C   1 
ATOM   4162 O  O   . LEU B 2 214 ? -38.901 -5.227  -13.008 1   31.73  ? 384 LEU B O   1 
ATOM   4163 C  CB  . LEU B 2 214 ? -38.01  -6.997  -15.52  1   27.26  ? 384 LEU B CB  1 
ATOM   4164 C  CG  . LEU B 2 214 ? -36.713 -7.269  -16.286 1   24.99  ? 384 LEU B CG  1 
ATOM   4165 C  CD1 . LEU B 2 214 ? -36.892 -7.01   -17.759 1   24.03  ? 384 LEU B CD1 1 
ATOM   4166 C  CD2 . LEU B 2 214 ? -35.571 -6.437  -15.715 1   23.33  ? 384 LEU B CD2 1 
ATOM   4167 N  N   . GLU B 2 215 ? -40.126 -7.128  -12.997 1   38.98  ? 385 GLU B N   1 
ATOM   4168 C  CA  . GLU B 2 215 ? -41.233 -6.555  -12.236 1   39.91  ? 385 GLU B CA  1 
ATOM   4169 C  C   . GLU B 2 215 ? -40.683 -6.024  -10.911 1   36.65  ? 385 GLU B C   1 
ATOM   4170 O  O   . GLU B 2 215 ? -40.845 -4.853  -10.593 1   33.23  ? 385 GLU B O   1 
ATOM   4171 C  CB  . GLU B 2 215 ? -42.302 -7.603  -11.94  1   47.85  ? 385 GLU B CB  1 
ATOM   4172 C  CG  . GLU B 2 215 ? -43.048 -8.113  -13.169 1   60.52  ? 385 GLU B CG  1 
ATOM   4173 C  CD  . GLU B 2 215 ? -44.05  -9.204  -12.839 1   77.58  ? 385 GLU B CD  1 
ATOM   4174 O  OE1 . GLU B 2 215 ? -44.02  -9.688  -11.688 1   93.17  ? 385 GLU B OE1 1 
ATOM   4175 O  OE2 . GLU B 2 215 ? -44.854 -9.582  -13.724 1   75.72  ? 385 GLU B OE2 1 
ATOM   4176 N  N   . THR B 2 216 ? -39.971 -6.873  -10.16  1   33.85  ? 386 THR B N   1 
ATOM   4177 C  CA  . THR B 2 216 ? -39.63  -6.502  -8.801  1   32.33  ? 386 THR B CA  1 
ATOM   4178 C  C   . THR B 2 216 ? -38.465 -5.51   -8.798  1   30.02  ? 386 THR B C   1 
ATOM   4179 O  O   . THR B 2 216 ? -38.388 -4.673  -7.903  1   31.45  ? 386 THR B O   1 
ATOM   4180 C  CB  . THR B 2 216 ? -39.463 -7.736  -7.903  1   35.15  ? 386 THR B CB  1 
ATOM   4181 O  OG1 . THR B 2 216 ? -38.231 -8.375  -8.207  1   33.54  ? 386 THR B OG1 1 
ATOM   4182 C  CG2 . THR B 2 216 ? -40.638 -8.706  -7.98   1   34.82  ? 386 THR B CG2 1 
ATOM   4183 N  N   . LEU B 2 217 ? -37.617 -5.547  -9.837  1   29.19  ? 387 LEU B N   1 
ATOM   4184 C  CA  . LEU B 2 217 ? -36.491 -4.623  -9.979  1   29.71  ? 387 LEU B CA  1 
ATOM   4185 C  C   . LEU B 2 217 ? -36.889 -3.235  -10.498 1   30.21  ? 387 LEU B C   1 
ATOM   4186 O  O   . LEU B 2 217 ? -36.096 -2.308  -10.361 1   29.87  ? 387 LEU B O   1 
ATOM   4187 C  CB  . LEU B 2 217 ? -35.403 -5.218  -10.871 1   28.68  ? 387 LEU B CB  1 
ATOM   4188 C  CG  . LEU B 2 217 ? -34.773 -6.512  -10.362 1   28.98  ? 387 LEU B CG  1 
ATOM   4189 C  CD1 . LEU B 2 217 ? -33.847 -7.135  -11.402 1   28.28  ? 387 LEU B CD1 1 
ATOM   4190 C  CD2 . LEU B 2 217 ? -34.063 -6.249  -9.044  1   28.96  ? 387 LEU B CD2 1 
ATOM   4191 N  N   . LYS B 2 218 ? -38.088 -3.086  -11.091 1   28.88  ? 388 LYS B N   1 
ATOM   4192 C  CA  . LYS B 2 218 ? -38.496 -1.89   -11.819 1   27.14  ? 388 LYS B CA  1 
ATOM   4193 C  C   . LYS B 2 218 ? -38.296 -0.59   -11.037 1   28.48  ? 388 LYS B C   1 
ATOM   4194 O  O   . LYS B 2 218 ? -37.717 0.358   -11.564 1   30.4   ? 388 LYS B O   1 
ATOM   4195 C  CB  . LYS B 2 218 ? -39.947 -2.003  -12.279 1   30.37  ? 388 LYS B CB  1 
ATOM   4196 C  CG  . LYS B 2 218 ? -40.487 -0.816  -13.056 1   33.93  ? 388 LYS B CG  1 
ATOM   4197 C  CD  . LYS B 2 218 ? -41.71  -1.172  -13.903 1   34.66  ? 388 LYS B CD  1 
ATOM   4198 C  CE  . LYS B 2 218 ? -42.272 0.037   -14.622 1   38.91  ? 388 LYS B CE  1 
ATOM   4199 N  NZ  . LYS B 2 218 ? -43.543 -0.212  -15.312 1   39.34  ? 388 LYS B NZ  1 
ATOM   4200 N  N   . PRO B 2 219 ? -38.805 -0.422  -9.798  1   27.98  ? 389 PRO B N   1 
ATOM   4201 C  CA  . PRO B 2 219 ? -38.55  0.829   -9.076  1   27.3   ? 389 PRO B CA  1 
ATOM   4202 C  C   . PRO B 2 219 ? -37.069 1.229   -9.087  1   29.53  ? 389 PRO B C   1 
ATOM   4203 O  O   . PRO B 2 219 ? -36.701 2.333   -9.51   1   30.44  ? 389 PRO B O   1 
ATOM   4204 C  CB  . PRO B 2 219 ? -39.083 0.535   -7.66   1   24.56  ? 389 PRO B CB  1 
ATOM   4205 C  CG  . PRO B 2 219 ? -40.108 -0.567  -7.854  1   21.86  ? 389 PRO B CG  1 
ATOM   4206 C  CD  . PRO B 2 219 ? -39.625 -1.382  -9.038  1   25.35  ? 389 PRO B CD  1 
ATOM   4207 N  N   . CYS B 2 220 ? -36.214 0.311   -8.622  1   27.52  ? 390 CYS B N   1 
ATOM   4208 C  CA  . CYS B 2 220 ? -34.783 0.555   -8.513  1   27.54  ? 390 CYS B CA  1 
ATOM   4209 C  C   . CYS B 2 220 ? -34.157 0.922   -9.865  1   30.33  ? 390 CYS B C   1 
ATOM   4210 O  O   . CYS B 2 220 ? -33.35  1.856   -9.975  1   30.71  ? 390 CYS B O   1 
ATOM   4211 C  CB  . CYS B 2 220 ? -34.113 -0.692  -7.974  1   26.58  ? 390 CYS B CB  1 
ATOM   4212 S  SG  . CYS B 2 220 ? -32.376 -0.419  -7.606  1   28.2   ? 390 CYS B SG  1 
ATOM   4213 N  N   . LEU B 2 221 ? -34.567 0.176   -10.895 1   27.38  ? 391 LEU B N   1 
ATOM   4214 C  CA  . LEU B 2 221 ? -34.049 0.295   -12.238 1   27.39  ? 391 LEU B CA  1 
ATOM   4215 C  C   . LEU B 2 221 ? -34.409 1.663   -12.819 1   27.54  ? 391 LEU B C   1 
ATOM   4216 O  O   . LEU B 2 221 ? -33.594 2.288   -13.491 1   29.69  ? 391 LEU B O   1 
ATOM   4217 C  CB  . LEU B 2 221 ? -34.744 -0.855  -12.964 1   32.3   ? 391 LEU B CB  1 
ATOM   4218 C  CG  . LEU B 2 221 ? -34.13  -1.352  -14.274 1   35.89  ? 391 LEU B CG  1 
ATOM   4219 C  CD1 . LEU B 2 221 ? -32.619 -1.471  -14.147 1   35.89  ? 391 LEU B CD1 1 
ATOM   4220 C  CD2 . LEU B 2 221 ? -34.728 -2.735  -14.537 1   40.08  ? 391 LEU B CD2 1 
ATOM   4221 N  N   . LEU B 2 222 ? -35.619 2.146   -12.545 1   26.16  ? 392 LEU B N   1 
ATOM   4222 C  CA  . LEU B 2 222 ? -36.028 3.48    -12.957 1   25.19  ? 392 LEU B CA  1 
ATOM   4223 C  C   . LEU B 2 222 ? -35.136 4.566   -12.345 1   28.83  ? 392 LEU B C   1 
ATOM   4224 O  O   . LEU B 2 222 ? -34.8   5.529   -13.038 1   33.14  ? 392 LEU B O   1 
ATOM   4225 C  CB  . LEU B 2 222 ? -37.501 3.724   -12.642 1   22.99  ? 392 LEU B CB  1 
ATOM   4226 C  CG  . LEU B 2 222 ? -38.495 3.035   -13.588 1   23.58  ? 392 LEU B CG  1 
ATOM   4227 C  CD1 . LEU B 2 222 ? -39.872 3.626   -13.405 1   21.07  ? 392 LEU B CD1 1 
ATOM   4228 C  CD2 . LEU B 2 222 ? -38.125 3.098   -15.061 1   22.25  ? 392 LEU B CD2 1 
ATOM   4229 N  N   . ASP B 2 223 ? -34.757 4.418   -11.062 1   27.94  ? 393 ASP B N   1 
ATOM   4230 C  CA  . ASP B 2 223 ? -33.896 5.396   -10.415 1   27.14  ? 393 ASP B CA  1 
ATOM   4231 C  C   . ASP B 2 223 ? -32.487 5.303   -10.983 1   26.24  ? 393 ASP B C   1 
ATOM   4232 O  O   . ASP B 2 223 ? -31.862 6.319   -11.268 1   25.69  ? 393 ASP B O   1 
ATOM   4233 C  CB  . ASP B 2 223 ? -33.819 5.203   -8.907  1   31.19  ? 393 ASP B CB  1 
ATOM   4234 C  CG  . ASP B 2 223 ? -35.082 5.531   -8.129  1   31.27  ? 393 ASP B CG  1 
ATOM   4235 O  OD1 . ASP B 2 223 ? -35.756 6.498   -8.526  1   29.03  ? 393 ASP B OD1 1 
ATOM   4236 O  OD2 . ASP B 2 223 ? -35.348 4.837   -7.115  1   33.58  ? 393 ASP B OD2 1 
ATOM   4237 N  N   . LEU B 2 224 ? -31.989 4.07    -11.101 1   25.32  ? 394 LEU B N   1 
ATOM   4238 C  CA  . LEU B 2 224 ? -30.63  3.839   -11.555 1   25.6   ? 394 LEU B CA  1 
ATOM   4239 C  C   . LEU B 2 224 ? -30.476 4.367   -12.969 1   26.56  ? 394 LEU B C   1 
ATOM   4240 O  O   . LEU B 2 224 ? -29.431 4.898   -13.331 1   29.02  ? 394 LEU B O   1 
ATOM   4241 C  CB  . LEU B 2 224 ? -30.277 2.361   -11.5   1   25.73  ? 394 LEU B CB  1 
ATOM   4242 C  CG  . LEU B 2 224 ? -28.781 2.06    -11.44  1   26.24  ? 394 LEU B CG  1 
ATOM   4243 C  CD1 . LEU B 2 224 ? -28.14  2.725   -10.235 1   26.43  ? 394 LEU B CD1 1 
ATOM   4244 C  CD2 . LEU B 2 224 ? -28.586 0.561   -11.385 1   25.09  ? 394 LEU B CD2 1 
ATOM   4245 N  N   . HIS B 2 225 ? -31.545 4.227   -13.744 1   25.12  ? 395 HIS B N   1 
ATOM   4246 C  CA  . HIS B 2 225 ? -31.553 4.702   -15.108 1   26.45  ? 395 HIS B CA  1 
ATOM   4247 C  C   . HIS B 2 225 ? -31.49  6.233   -15.138 1   29.07  ? 395 HIS B C   1 
ATOM   4248 O  O   . HIS B 2 225 ? -30.819 6.775   -16.017 1   29.4   ? 395 HIS B O   1 
ATOM   4249 C  CB  . HIS B 2 225 ? -32.717 4.053   -15.851 1   24.31  ? 395 HIS B CB  1 
ATOM   4250 C  CG  . HIS B 2 225 ? -32.896 4.546   -17.236 1   27.54  ? 395 HIS B CG  1 
ATOM   4251 N  ND1 . HIS B 2 225 ? -31.944 4.318   -18.212 1   29.98  ? 395 HIS B ND1 1 
ATOM   4252 C  CD2 . HIS B 2 225 ? -33.907 5.207   -17.829 1   28.37  ? 395 HIS B CD2 1 
ATOM   4253 C  CE1 . HIS B 2 225 ? -32.364 4.827   -19.354 1   28.3   ? 395 HIS B CE1 1 
ATOM   4254 N  NE2 . HIS B 2 225 ? -33.556 5.366   -19.146 1   29.53  ? 395 HIS B NE2 1 
ATOM   4255 N  N   . GLN B 2 226 ? -32.196 6.92    -14.218 1   28.11  ? 396 GLN B N   1 
ATOM   4256 C  CA  . GLN B 2 226 ? -32.126 8.37    -14.146 1   31.85  ? 396 GLN B CA  1 
ATOM   4257 C  C   . GLN B 2 226 ? -30.712 8.774   -13.734 1   32.12  ? 396 GLN B C   1 
ATOM   4258 O  O   . GLN B 2 226 ? -30.134 9.708   -14.279 1   36.33  ? 396 GLN B O   1 
ATOM   4259 C  CB  . GLN B 2 226 ? -33.132 9.023   -13.196 1   37.84  ? 396 GLN B CB  1 
ATOM   4260 C  CG  . GLN B 2 226 ? -34.573 9.12    -13.698 1   51.23  ? 396 GLN B CG  1 
ATOM   4261 C  CD  . GLN B 2 226 ? -34.739 9.815   -15.039 1   65.77  ? 396 GLN B CD  1 
ATOM   4262 O  OE1 . GLN B 2 226 ? -35.278 9.247   -15.998 1   67.85  ? 396 GLN B OE1 1 
ATOM   4263 N  NE2 . GLN B 2 226 ? -34.295 11.06   -15.131 1   64.1   ? 396 GLN B NE2 1 
ATOM   4264 N  N   . THR B 2 227 ? -30.161 8.062   -12.753 1   30.8   ? 397 THR B N   1 
ATOM   4265 C  CA  . THR B 2 227 ? -28.865 8.411   -12.209 1   26.69  ? 397 THR B CA  1 
ATOM   4266 C  C   . THR B 2 227 ? -27.848 8.289   -13.331 1   25.76  ? 397 THR B C   1 
ATOM   4267 O  O   . THR B 2 227 ? -26.985 9.132   -13.462 1   30.26  ? 397 THR B O   1 
ATOM   4268 C  CB  . THR B 2 227 ? -28.528 7.484   -11.042 1   26.32  ? 397 THR B CB  1 
ATOM   4269 O  OG1 . THR B 2 227 ? -29.474 7.798   -10.022 1   26.84  ? 397 THR B OG1 1 
ATOM   4270 C  CG2 . THR B 2 227 ? -27.089 7.626   -10.572 1   23.84  ? 397 THR B CG2 1 
ATOM   4271 N  N   . TYR B 2 228 ? -27.954 7.222   -14.119 1   24.69  ? 398 TYR B N   1 
ATOM   4272 C  CA  . TYR B 2 228 ? -27.037 6.974   -15.21  1   25.1   ? 398 TYR B CA  1 
ATOM   4273 C  C   . TYR B 2 228 ? -27.18  8.081   -16.251 1   27.69  ? 398 TYR B C   1 
ATOM   4274 O  O   . TYR B 2 228 ? -26.174 8.565   -16.758 1   30.89  ? 398 TYR B O   1 
ATOM   4275 C  CB  . TYR B 2 228 ? -27.32  5.588   -15.783 1   24.42  ? 398 TYR B CB  1 
ATOM   4276 C  CG  . TYR B 2 228 ? -26.344 5.092   -16.834 1   26.22  ? 398 TYR B CG  1 
ATOM   4277 C  CD1 . TYR B 2 228 ? -25.087 5.662   -16.997 1   27.26  ? 398 TYR B CD1 1 
ATOM   4278 C  CD2 . TYR B 2 228 ? -26.677 4.01    -17.639 1   28.69  ? 398 TYR B CD2 1 
ATOM   4279 C  CE1 . TYR B 2 228 ? -24.196 5.179   -17.945 1   29.49  ? 398 TYR B CE1 1 
ATOM   4280 C  CE2 . TYR B 2 228 ? -25.782 3.506   -18.572 1   29.61  ? 398 TYR B CE2 1 
ATOM   4281 C  CZ  . TYR B 2 228 ? -24.539 4.094   -18.734 1   30.52  ? 398 TYR B CZ  1 
ATOM   4282 O  OH  . TYR B 2 228 ? -23.67  3.611   -19.681 1   35.1   ? 398 TYR B OH  1 
ATOM   4283 N  N   . LEU B 2 229 ? -28.421 8.496   -16.542 1   25.69  ? 399 LEU B N   1 
ATOM   4284 C  CA  . LEU B 2 229 ? -28.684 9.519   -17.535 1   24.61  ? 399 LEU B CA  1 
ATOM   4285 C  C   . LEU B 2 229 ? -28.046 10.837  -17.129 1   26.49  ? 399 LEU B C   1 
ATOM   4286 O  O   . LEU B 2 229 ? -27.495 11.525  -17.982 1   26.05  ? 399 LEU B O   1 
ATOM   4287 C  CB  . LEU B 2 229 ? -30.182 9.675   -17.757 1   24.07  ? 399 LEU B CB  1 
ATOM   4288 C  CG  . LEU B 2 229 ? -30.776 8.788   -18.859 1   24.96  ? 399 LEU B CG  1 
ATOM   4289 C  CD1 . LEU B 2 229 ? -32.273 8.825   -18.771 1   25.03  ? 399 LEU B CD1 1 
ATOM   4290 C  CD2 . LEU B 2 229 ? -30.357 9.165   -20.272 1   24.52  ? 399 LEU B CD2 1 
ATOM   4291 N  N   . ARG B 2 230 ? -28.117 11.161  -15.832 1   29.56  ? 400 ARG B N   1 
ATOM   4292 C  CA  . ARG B 2 230 ? -27.733 12.47   -15.323 1   32.56  ? 400 ARG B CA  1 
ATOM   4293 C  C   . ARG B 2 230 ? -26.296 12.473  -14.806 1   30.75  ? 400 ARG B C   1 
ATOM   4294 O  O   . ARG B 2 230 ? -25.83  13.494  -14.293 1   30.73  ? 400 ARG B O   1 
ATOM   4295 C  CB  . ARG B 2 230 ? -28.684 12.913  -14.205 1   35.71  ? 400 ARG B CB  1 
ATOM   4296 C  CG  . ARG B 2 230 ? -30.118 13.084  -14.686 1   44.86  ? 400 ARG B CG  1 
ATOM   4297 C  CD  . ARG B 2 230 ? -31.081 13.168  -13.517 1   61.54  ? 400 ARG B CD  1 
ATOM   4298 N  NE  . ARG B 2 230 ? -32.484 13.331  -13.925 1   77.99  ? 400 ARG B NE  1 
ATOM   4299 C  CZ  . ARG B 2 230 ? -33.387 14.128  -13.347 1   83.3   ? 400 ARG B CZ  1 
ATOM   4300 N  NH1 . ARG B 2 230 ? -33.063 14.841  -12.279 1   82.43  ? 400 ARG B NH1 1 
ATOM   4301 N  NH2 . ARG B 2 230 ? -34.624 14.183  -13.818 1   77.55  ? 400 ARG B NH2 1 
ATOM   4302 N  N   . ALA B 2 231 ? -25.587 11.353  -14.956 1   26.1   ? 401 ALA B N   1 
ATOM   4303 C  CA  . ALA B 2 231 ? -24.29  11.229  -14.298 1   27.84  ? 401 ALA B CA  1 
ATOM   4304 C  C   . ALA B 2 231 ? -23.313 12.341  -14.739 1   28.4   ? 401 ALA B C   1 
ATOM   4305 O  O   . ALA B 2 231 ? -22.538 12.857  -13.934 1   29.29  ? 401 ALA B O   1 
ATOM   4306 C  CB  . ALA B 2 231 ? -23.751 9.826   -14.485 1   23.67  ? 401 ALA B CB  1 
ATOM   4307 N  N   . PRO B 2 232 ? -23.297 12.771  -16.019 1   25.35  ? 402 PRO B N   1 
ATOM   4308 C  CA  . PRO B 2 232 ? -22.45  13.893  -16.425 1   26.41  ? 402 PRO B CA  1 
ATOM   4309 C  C   . PRO B 2 232 ? -22.73  15.214  -15.707 1   27.14  ? 402 PRO B C   1 
ATOM   4310 O  O   . PRO B 2 232 ? -21.848 16.059  -15.627 1   26.95  ? 402 PRO B O   1 
ATOM   4311 C  CB  . PRO B 2 232 ? -22.742 14.015  -17.933 1   23.84  ? 402 PRO B CB  1 
ATOM   4312 C  CG  . PRO B 2 232 ? -23.211 12.631  -18.338 1   22.98  ? 402 PRO B CG  1 
ATOM   4313 C  CD  . PRO B 2 232 ? -24.027 12.175  -17.149 1   24.62  ? 402 PRO B CD  1 
ATOM   4314 N  N   . GLN B 2 233 ? -23.945 15.389  -15.175 1   28.08  ? 403 GLN B N   1 
ATOM   4315 C  CA  . GLN B 2 233 ? -24.357 16.663  -14.589 1   29     ? 403 GLN B CA  1 
ATOM   4316 C  C   . GLN B 2 233 ? -24.25  16.656  -13.059 1   28.06  ? 403 GLN B C   1 
ATOM   4317 O  O   . GLN B 2 233 ? -24.301 17.713  -12.44  1   26.04  ? 403 GLN B O   1 
ATOM   4318 C  CB  . GLN B 2 233 ? -25.792 17.031  -14.981 1   30.2   ? 403 GLN B CB  1 
ATOM   4319 C  CG  . GLN B 2 233 ? -25.954 17.583  -16.393 1   34.54  ? 403 GLN B CG  1 
ATOM   4320 C  CD  . GLN B 2 233 ? -25.74  16.562  -17.495 1   40.88  ? 403 GLN B CD  1 
ATOM   4321 O  OE1 . GLN B 2 233 ? -24.963 16.78   -18.439 1   40.56  ? 403 GLN B OE1 1 
ATOM   4322 N  NE2 . GLN B 2 233 ? -26.461 15.448  -17.4   1   37.96  ? 403 GLN B NE2 1 
ATOM   4323 N  N   . HIS B 2 234 ? -24.158 15.47   -12.446 1   27.13  ? 404 HIS B N   1 
ATOM   4324 C  CA  . HIS B 2 234 ? -24.066 15.364  -10.998 1   27.69  ? 404 HIS B CA  1 
ATOM   4325 C  C   . HIS B 2 234 ? -22.837 16.136  -10.531 1   28.04  ? 404 HIS B C   1 
ATOM   4326 O  O   . HIS B 2 234 ? -21.791 16.08   -11.16  1   30.5   ? 404 HIS B O   1 
ATOM   4327 C  CB  . HIS B 2 234 ? -23.916 13.894  -10.581 1   28.74  ? 404 HIS B CB  1 
ATOM   4328 C  CG  . HIS B 2 234 ? -24.242 13.552  -9.161  1   30.11  ? 404 HIS B CG  1 
ATOM   4329 N  ND1 . HIS B 2 234 ? -23.513 13.973  -8.063  1   31.89  ? 404 HIS B ND1 1 
ATOM   4330 C  CD2 . HIS B 2 234 ? -25.212 12.762  -8.681  1   27.33  ? 404 HIS B CD2 1 
ATOM   4331 C  CE1 . HIS B 2 234 ? -24.049 13.465  -6.966  1   29.42  ? 404 HIS B CE1 1 
ATOM   4332 N  NE2 . HIS B 2 234 ? -25.077 12.721  -7.323  1   27.73  ? 404 HIS B NE2 1 
ATOM   4333 N  N   . ALA B 2 235 ? -22.97  16.831  -9.401  1   27.15  ? 405 ALA B N   1 
ATOM   4334 C  CA  . ALA B 2 235 ? -21.891 17.555  -8.747  1   25     ? 405 ALA B CA  1 
ATOM   4335 C  C   . ALA B 2 235 ? -20.68  16.662  -8.471  1   28.58  ? 405 ALA B C   1 
ATOM   4336 O  O   . ALA B 2 235 ? -19.545 17.133  -8.443  1   29.39  ? 405 ALA B O   1 
ATOM   4337 C  CB  . ALA B 2 235 ? -22.45  18.07   -7.448  1   23.43  ? 405 ALA B CB  1 
ATOM   4338 N  N   . GLN B 2 236 ? -20.933 15.386  -8.148  1   29.64  ? 406 GLN B N   1 
ATOM   4339 C  CA  . GLN B 2 236 ? -19.868 14.459  -7.825  1   30.93  ? 406 GLN B CA  1 
ATOM   4340 C  C   . GLN B 2 236 ? -19.507 13.673  -9.078  1   30.7   ? 406 GLN B C   1 
ATOM   4341 O  O   . GLN B 2 236 ? -20.385 13.131  -9.75   1   30.57  ? 406 GLN B O   1 
ATOM   4342 C  CB  . GLN B 2 236 ? -20.316 13.545  -6.69   1   33.55  ? 406 GLN B CB  1 
ATOM   4343 C  CG  . GLN B 2 236 ? -20.109 14.132  -5.3    1   36.5   ? 406 GLN B CG  1 
ATOM   4344 C  CD  . GLN B 2 236 ? -20.914 15.384  -5.064  1   40.52  ? 406 GLN B CD  1 
ATOM   4345 O  OE1 . GLN B 2 236 ? -22.134 15.411  -5.266  1   43.57  ? 406 GLN B OE1 1 
ATOM   4346 N  NE2 . GLN B 2 236 ? -20.222 16.427  -4.629  1   38.89  ? 406 GLN B NE2 1 
ATOM   4347 N  N   . GLN B 2 237 ? -18.2   13.596  -9.354  1   28.64  ? 407 GLN B N   1 
ATOM   4348 C  CA  . GLN B 2 237 ? -17.698 13.209  -10.666 1   25.45  ? 407 GLN B CA  1 
ATOM   4349 C  C   . GLN B 2 237 ? -16.57  12.182  -10.562 1   25.46  ? 407 GLN B C   1 
ATOM   4350 O  O   . GLN B 2 237 ? -16.109 11.684  -11.592 1   27.92  ? 407 GLN B O   1 
ATOM   4351 C  CB  . GLN B 2 237 ? -17.23  14.455  -11.419 1   20.3   ? 407 GLN B CB  1 
ATOM   4352 C  CG  . GLN B 2 237 ? -18.385 15.253  -12.008 1   19.97  ? 407 GLN B CG  1 
ATOM   4353 C  CD  . GLN B 2 237 ? -19.103 14.483  -13.093 1   22.32  ? 407 GLN B CD  1 
ATOM   4354 O  OE1 . GLN B 2 237 ? -18.474 13.746  -13.86  1   27.72  ? 407 GLN B OE1 1 
ATOM   4355 N  NE2 . GLN B 2 237 ? -20.421 14.581  -13.148 1   19.89  ? 407 GLN B NE2 1 
ATOM   4356 N  N   . SER B 2 238 ? -16.15  11.856  -9.335  1   21.94  ? 408 SER B N   1 
ATOM   4357 C  CA  . SER B 2 238 ? -14.97  11.033  -9.139  1   23.79  ? 408 SER B CA  1 
ATOM   4358 C  C   . SER B 2 238 ? -15.186 9.61    -9.672  1   24.99  ? 408 SER B C   1 
ATOM   4359 O  O   . SER B 2 238 ? -14.239 8.964   -10.111 1   24.84  ? 408 SER B O   1 
ATOM   4360 C  CB  . SER B 2 238 ? -14.573 11.026  -7.679  1   25.21  ? 408 SER B CB  1 
ATOM   4361 O  OG  . SER B 2 238 ? -14.105 12.305  -7.287  1   27.58  ? 408 SER B OG  1 
ATOM   4362 N  N   . ILE B 2 239 ? -16.427 9.122   -9.626  1   22.68  ? 409 ILE B N   1 
ATOM   4363 C  CA  . ILE B 2 239 ? -16.706 7.784   -10.1   1   23.04  ? 409 ILE B CA  1 
ATOM   4364 C  C   . ILE B 2 239 ? -16.607 7.776   -11.629 1   23.03  ? 409 ILE B C   1 
ATOM   4365 O  O   . ILE B 2 239 ? -15.935 6.909   -12.189 1   22.48  ? 409 ILE B O   1 
ATOM   4366 C  CB  . ILE B 2 239 ? -18.043 7.252   -9.537  1   24.26  ? 409 ILE B CB  1 
ATOM   4367 C  CG1 . ILE B 2 239 ? -17.955 7.018   -8.042  1   27.53  ? 409 ILE B CG1 1 
ATOM   4368 C  CG2 . ILE B 2 239 ? -18.467 5.957   -10.222 1   22.8   ? 409 ILE B CG2 1 
ATOM   4369 C  CD1 . ILE B 2 239 ? -19.294 6.769   -7.364  1   32.1   ? 409 ILE B CD1 1 
ATOM   4370 N  N   . ARG B 2 240 ? -17.215 8.767   -12.302 1   21.97  ? 410 ARG B N   1 
ATOM   4371 C  CA  . ARG B 2 240 ? -17.082 8.87    -13.752 1   21.85  ? 410 ARG B CA  1 
ATOM   4372 C  C   . ARG B 2 240 ? -15.611 8.986   -14.137 1   22.55  ? 410 ARG B C   1 
ATOM   4373 O  O   . ARG B 2 240 ? -15.192 8.316   -15.08  1   22.71  ? 410 ARG B O   1 
ATOM   4374 C  CB  . ARG B 2 240 ? -17.832 10.038  -14.391 1   21.34  ? 410 ARG B CB  1 
ATOM   4375 C  CG  . ARG B 2 240 ? -19.327 9.786   -14.46  1   22.98  ? 410 ARG B CG  1 
ATOM   4376 C  CD  . ARG B 2 240 ? -20.108 10.916  -15.085 1   24.5   ? 410 ARG B CD  1 
ATOM   4377 N  NE  . ARG B 2 240 ? -19.878 10.855  -16.525 1   25.26  ? 410 ARG B NE  1 
ATOM   4378 C  CZ  . ARG B 2 240 ? -19.397 11.863  -17.236 1   25.68  ? 410 ARG B CZ  1 
ATOM   4379 N  NH1 . ARG B 2 240 ? -19.39  11.775  -18.555 1   23.75  ? 410 ARG B NH1 1 
ATOM   4380 N  NH2 . ARG B 2 240 ? -18.982 12.959  -16.63  1   24.06  ? 410 ARG B NH2 1 
ATOM   4381 N  N   . GLU B 2 241 ? -14.838 9.803   -13.399 1   22.7   ? 411 GLU B N   1 
ATOM   4382 C  CA  . GLU B 2 241 ? -13.434 9.991   -13.756 1   27     ? 411 GLU B CA  1 
ATOM   4383 C  C   . GLU B 2 241 ? -12.717 8.646   -13.626 1   27.15  ? 411 GLU B C   1 
ATOM   4384 O  O   . GLU B 2 241 ? -11.998 8.221   -14.527 1   28.03  ? 411 GLU B O   1 
ATOM   4385 C  CB  . GLU B 2 241 ? -12.653 11.037  -12.954 1   29.23  ? 411 GLU B CB  1 
ATOM   4386 C  CG  . GLU B 2 241 ? -13.271 12.433  -12.887 1   34.31  ? 411 GLU B CG  1 
ATOM   4387 C  CD  . GLU B 2 241 ? -13.393 13.188  -14.205 1   39.79  ? 411 GLU B CD  1 
ATOM   4388 O  OE1 . GLU B 2 241 ? -12.625 12.887  -15.144 1   36.34  ? 411 GLU B OE1 1 
ATOM   4389 O  OE2 . GLU B 2 241 ? -14.28  14.083  -14.281 1   47.86  ? 411 GLU B OE2 1 
ATOM   4390 N  N   . LYS B 2 242 ? -12.951 7.97    -12.5   1   24.8   ? 412 LYS B N   1 
ATOM   4391 C  CA  . LYS B 2 242 ? -12.338 6.681   -12.238 1   24.54  ? 412 LYS B CA  1 
ATOM   4392 C  C   . LYS B 2 242 ? -12.619 5.713   -13.388 1   24.71  ? 412 LYS B C   1 
ATOM   4393 O  O   . LYS B 2 242 ? -11.708 5.039   -13.844 1   27.02  ? 412 LYS B O   1 
ATOM   4394 C  CB  . LYS B 2 242 ? -12.855 6.138   -10.904 1   20.75  ? 412 LYS B CB  1 
ATOM   4395 C  CG  . LYS B 2 242 ? -12.502 4.708   -10.602 1   20.16  ? 412 LYS B CG  1 
ATOM   4396 C  CD  . LYS B 2 242 ? -13.121 4.356   -9.251  1   21.61  ? 412 LYS B CD  1 
ATOM   4397 C  CE  . LYS B 2 242 ? -13.084 2.901   -8.865  1   19.77  ? 412 LYS B CE  1 
ATOM   4398 N  NZ  . LYS B 2 242 ? -13.718 2.709   -7.553  1   19.52  ? 412 LYS B NZ  1 
ATOM   4399 N  N   . TYR B 2 243 ? -13.871 5.648   -13.85  1   22.83  ? 413 TYR B N   1 
ATOM   4400 C  CA  . TYR B 2 243 ? -14.269 4.626   -14.795 1   22.83  ? 413 TYR B CA  1 
ATOM   4401 C  C   . TYR B 2 243 ? -14     5.044   -16.242 1   24.95  ? 413 TYR B C   1 
ATOM   4402 O  O   . TYR B 2 243 ? -14.46  4.354   -17.141 1   26.45  ? 413 TYR B O   1 
ATOM   4403 C  CB  . TYR B 2 243 ? -15.704 4.155   -14.561 1   22.54  ? 413 TYR B CB  1 
ATOM   4404 C  CG  . TYR B 2 243 ? -15.821 3.128   -13.444 1   23.8   ? 413 TYR B CG  1 
ATOM   4405 C  CD1 . TYR B 2 243 ? -15.848 3.526   -12.113 1   24.84  ? 413 TYR B CD1 1 
ATOM   4406 C  CD2 . TYR B 2 243 ? -15.922 1.77    -13.718 1   23.16  ? 413 TYR B CD2 1 
ATOM   4407 C  CE1 . TYR B 2 243 ? -15.965 2.613   -11.076 1   25.42  ? 413 TYR B CE1 1 
ATOM   4408 C  CE2 . TYR B 2 243 ? -16.033 0.846   -12.695 1   26.07  ? 413 TYR B CE2 1 
ATOM   4409 C  CZ  . TYR B 2 243 ? -16.032 1.266   -11.37  1   28.26  ? 413 TYR B CZ  1 
ATOM   4410 O  OH  . TYR B 2 243 ? -16.123 0.359   -10.359 1   29.89  ? 413 TYR B OH  1 
ATOM   4411 N  N   . LYS B 2 244 ? -13.228 6.113   -16.477 1   24.55  ? 414 LYS B N   1 
ATOM   4412 C  CA  . LYS B 2 244 ? -12.637 6.359   -17.792 1   26.15  ? 414 LYS B CA  1 
ATOM   4413 C  C   . LYS B 2 244 ? -11.391 5.498   -18.001 1   26.61  ? 414 LYS B C   1 
ATOM   4414 O  O   . LYS B 2 244 ? -10.951 5.297   -19.134 1   27.39  ? 414 LYS B O   1 
ATOM   4415 C  CB  . LYS B 2 244 ? -12.196 7.812   -17.994 1   25.82  ? 414 LYS B CB  1 
ATOM   4416 C  CG  . LYS B 2 244 ? -13.352 8.757   -18.217 1   28.9   ? 414 LYS B CG  1 
ATOM   4417 C  CD  . LYS B 2 244 ? -12.991 10.236  -18.216 1   30.94  ? 414 LYS B CD  1 
ATOM   4418 C  CE  . LYS B 2 244 ? -14.272 11.035  -18.263 1   35.2   ? 414 LYS B CE  1 
ATOM   4419 N  NZ  . LYS B 2 244 ? -13.993 12.389  -17.778 1   39.39  ? 414 LYS B NZ  1 
ATOM   4420 N  N   . ASN B 2 245 ? -10.83  5.002   -16.894 1   25.99  ? 415 ASN B N   1 
ATOM   4421 C  CA  . ASN B 2 245 ? -9.584  4.263   -16.898 1   28.1   ? 415 ASN B CA  1 
ATOM   4422 C  C   . ASN B 2 245 ? -9.775  2.94    -17.633 1   27.55  ? 415 ASN B C   1 
ATOM   4423 O  O   . ASN B 2 245 ? -10.827 2.318   -17.558 1   25.97  ? 415 ASN B O   1 
ATOM   4424 C  CB  . ASN B 2 245 ? -9.089  4.069   -15.469 1   34.43  ? 415 ASN B CB  1 
ATOM   4425 C  CG  . ASN B 2 245 ? -7.62   3.724   -15.379 1   38.52  ? 415 ASN B CG  1 
ATOM   4426 O  OD1 . ASN B 2 245 ? -7.225  2.573   -15.607 1   40.96  ? 415 ASN B OD1 1 
ATOM   4427 N  ND2 . ASN B 2 245 ? -6.801  4.711   -15.038 1   39.73  ? 415 ASN B ND2 1 
ATOM   4428 N  N   . SER B 2 246 ? -8.724  2.51    -18.33  1   30.33  ? 416 SER B N   1 
ATOM   4429 C  CA  . SER B 2 246 ? -8.768  1.279   -19.098 1   31.43  ? 416 SER B CA  1 
ATOM   4430 C  C   . SER B 2 246 ? -8.948  0.081   -18.168 1   29.01  ? 416 SER B C   1 
ATOM   4431 O  O   . SER B 2 246 ? -9.565  -0.898  -18.554 1   28.1   ? 416 SER B O   1 
ATOM   4432 C  CB  . SER B 2 246 ? -7.569  1.153   -19.976 1   33.15  ? 416 SER B CB  1 
ATOM   4433 O  OG  . SER B 2 246 ? -6.419  1.309   -19.161 1   43.4   ? 416 SER B OG  1 
ATOM   4434 N  N   . LYS B 2 247 ? -8.463  0.187   -16.927 1   28.81  ? 417 LYS B N   1 
ATOM   4435 C  CA  . LYS B 2 247 ? -8.63   -0.856  -15.923 1   31.88  ? 417 LYS B CA  1 
ATOM   4436 C  C   . LYS B 2 247 ? -10.104 -1.262  -15.799 1   35.52  ? 417 LYS B C   1 
ATOM   4437 O  O   . LYS B 2 247 ? -10.414 -2.425  -15.543 1   35.31  ? 417 LYS B O   1 
ATOM   4438 C  CB  . LYS B 2 247 ? -8.115  -0.269  -14.609 1   34.37  ? 417 LYS B CB  1 
ATOM   4439 C  CG  . LYS B 2 247 ? -8.304  -1.103  -13.355 1   43.23  ? 417 LYS B CG  1 
ATOM   4440 C  CD  . LYS B 2 247 ? -8.059  -0.272  -12.092 1   55.54  ? 417 LYS B CD  1 
ATOM   4441 C  CE  . LYS B 2 247 ? -7.528  -0.989  -10.873 1   58.01  ? 417 LYS B CE  1 
ATOM   4442 N  NZ  . LYS B 2 247 ? -8.1    -2.331  -10.772 1   58.24  ? 417 LYS B NZ  1 
ATOM   4443 N  N   . TYR B 2 248 ? -11.013 -0.295  -16.002 1   32.48  ? 418 TYR B N   1 
ATOM   4444 C  CA  . TYR B 2 248 ? -12.445 -0.541  -16.038 1   29.77  ? 418 TYR B CA  1 
ATOM   4445 C  C   . TYR B 2 248 ? -13.016 -0.399  -17.454 1   28.54  ? 418 TYR B C   1 
ATOM   4446 O  O   . TYR B 2 248 ? -14.216 -0.204  -17.619 1   28.91  ? 418 TYR B O   1 
ATOM   4447 C  CB  . TYR B 2 248 ? -13.106 0.431   -15.052 1   34.18  ? 418 TYR B CB  1 
ATOM   4448 C  CG  . TYR B 2 248 ? -12.462 0.44    -13.67  1   34.59  ? 418 TYR B CG  1 
ATOM   4449 C  CD1 . TYR B 2 248 ? -12.658 -0.626  -12.781 1   33.38  ? 418 TYR B CD1 1 
ATOM   4450 C  CD2 . TYR B 2 248 ? -11.649 1.495   -13.272 1   31.34  ? 418 TYR B CD2 1 
ATOM   4451 C  CE1 . TYR B 2 248 ? -12.065 -0.647  -11.529 1   34.49  ? 418 TYR B CE1 1 
ATOM   4452 C  CE2 . TYR B 2 248 ? -11.053 1.484   -12.021 1   40.06  ? 418 TYR B CE2 1 
ATOM   4453 C  CZ  . TYR B 2 248 ? -11.248 0.41    -11.156 1   41.81  ? 418 TYR B CZ  1 
ATOM   4454 O  OH  . TYR B 2 248 ? -10.639 0.429   -9.928  1   46.89  ? 418 TYR B OH  1 
ATOM   4455 N  N   . HIS B 2 249 ? -12.172 -0.509  -18.48  1   24.3   ? 419 HIS B N   1 
ATOM   4456 C  CA  . HIS B 2 249 ? -12.637 -0.612  -19.85  1   26.15  ? 419 HIS B CA  1 
ATOM   4457 C  C   . HIS B 2 249 ? -13.286 0.688   -20.312 1   27.14  ? 419 HIS B C   1 
ATOM   4458 O  O   . HIS B 2 249 ? -13.983 0.696   -21.333 1   28.65  ? 419 HIS B O   1 
ATOM   4459 C  CB  . HIS B 2 249 ? -13.539 -1.832  -20.027 1   27.81  ? 419 HIS B CB  1 
ATOM   4460 C  CG  . HIS B 2 249 ? -12.903 -3.092  -19.537 1   35.36  ? 419 HIS B CG  1 
ATOM   4461 N  ND1 . HIS B 2 249 ? -13.093 -3.582  -18.255 1   38.93  ? 419 HIS B ND1 1 
ATOM   4462 C  CD2 . HIS B 2 249 ? -12.072 -3.964  -20.161 1   36.25  ? 419 HIS B CD2 1 
ATOM   4463 C  CE1 . HIS B 2 249 ? -12.396 -4.712  -18.116 1   40.01  ? 419 HIS B CE1 1 
ATOM   4464 N  NE2 . HIS B 2 249 ? -11.769 -4.958  -19.259 1   39.93  ? 419 HIS B NE2 1 
ATOM   4465 N  N   . GLY B 2 250 ? -13.029 1.768   -19.56  1   23.98  ? 420 GLY B N   1 
ATOM   4466 C  CA  . GLY B 2 250 ? -13.446 3.106   -19.936 1   22.77  ? 420 GLY B CA  1 
ATOM   4467 C  C   . GLY B 2 250 ? -14.964 3.233   -20.041 1   24.4   ? 420 GLY B C   1 
ATOM   4468 O  O   . GLY B 2 250 ? -15.444 4.063   -20.818 1   24.79  ? 420 GLY B O   1 
ATOM   4469 N  N   . VAL B 2 251 ? -15.696 2.442   -19.231 1   21.97  ? 421 VAL B N   1 
ATOM   4470 C  CA  . VAL B 2 251 ? -17.138 2.288   -19.376 1   21.29  ? 421 VAL B CA  1 
ATOM   4471 C  C   . VAL B 2 251 ? -17.907 3.579   -19.086 1   23.15  ? 421 VAL B C   1 
ATOM   4472 O  O   . VAL B 2 251 ? -19.035 3.71    -19.533 1   26.21  ? 421 VAL B O   1 
ATOM   4473 C  CB  . VAL B 2 251 ? -17.737 1.112   -18.584 1   20.24  ? 421 VAL B CB  1 
ATOM   4474 C  CG1 . VAL B 2 251 ? -17.296 -0.234  -19.151 1   19.05  ? 421 VAL B CG1 1 
ATOM   4475 C  CG2 . VAL B 2 251 ? -17.444 1.209   -17.093 1   19.87  ? 421 VAL B CG2 1 
ATOM   4476 N  N   . SER B 2 252 ? -17.347 4.529   -18.328 1   23.71  ? 422 SER B N   1 
ATOM   4477 C  CA  . SER B 2 252 ? -18.087 5.759   -18.055 1   22.89  ? 422 SER B CA  1 
ATOM   4478 C  C   . SER B 2 252 ? -18.25  6.585   -19.328 1   24.11  ? 422 SER B C   1 
ATOM   4479 O  O   . SER B 2 252 ? -19.004 7.546   -19.318 1   25.78  ? 422 SER B O   1 
ATOM   4480 C  CB  . SER B 2 252 ? -17.54  6.589   -16.889 1   20.68  ? 422 SER B CB  1 
ATOM   4481 O  OG  . SER B 2 252 ? -16.189 6.974   -17.081 1   20.22  ? 422 SER B OG  1 
ATOM   4482 N  N   . LEU B 2 253 ? -17.569 6.183   -20.414 1   24.73  ? 423 LEU B N   1 
ATOM   4483 C  CA  . LEU B 2 253 ? -17.63  6.856   -21.703 1   22.57  ? 423 LEU B CA  1 
ATOM   4484 C  C   . LEU B 2 253 ? -18.717 6.27    -22.607 1   23.23  ? 423 LEU B C   1 
ATOM   4485 O  O   . LEU B 2 253 ? -19.024 6.857   -23.641 1   23.69  ? 423 LEU B O   1 
ATOM   4486 C  CB  . LEU B 2 253 ? -16.249 6.744   -22.349 1   23.54  ? 423 LEU B CB  1 
ATOM   4487 C  CG  . LEU B 2 253 ? -15.103 7.487   -21.642 1   23.33  ? 423 LEU B CG  1 
ATOM   4488 C  CD1 . LEU B 2 253 ? -13.819 7.108   -22.366 1   21.63  ? 423 LEU B CD1 1 
ATOM   4489 C  CD2 . LEU B 2 253 ? -15.261 9.018   -21.624 1   22.36  ? 423 LEU B CD2 1 
ATOM   4490 N  N   . LEU B 2 254 ? -19.294 5.112   -22.24  1   23.96  ? 424 LEU B N   1 
ATOM   4491 C  CA  . LEU B 2 254 ? -20.404 4.524   -22.989 1   23.77  ? 424 LEU B CA  1 
ATOM   4492 C  C   . LEU B 2 254 ? -21.638 5.417   -22.87  1   25.32  ? 424 LEU B C   1 
ATOM   4493 O  O   . LEU B 2 254 ? -21.785 6.149   -21.893 1   24.95  ? 424 LEU B O   1 
ATOM   4494 C  CB  . LEU B 2 254 ? -20.709 3.13    -22.445 1   21.09  ? 424 LEU B CB  1 
ATOM   4495 C  CG  . LEU B 2 254 ? -19.649 2.059   -22.713 1   19.08  ? 424 LEU B CG  1 
ATOM   4496 C  CD1 . LEU B 2 254 ? -20.076 0.74    -22.117 1   17.63  ? 424 LEU B CD1 1 
ATOM   4497 C  CD2 . LEU B 2 254 ? -19.443 1.927   -24.215 1   17.88  ? 424 LEU B CD2 1 
ATOM   4498 N  N   . ASN B 2 255 ? -22.528 5.353   -23.871 1   26.95  ? 425 ASN B N   1 
ATOM   4499 C  CA  . ASN B 2 255 ? -23.757 6.14    -23.847 1   26.78  ? 425 ASN B CA  1 
ATOM   4500 C  C   . ASN B 2 255 ? -24.884 5.358   -23.176 1   26.49  ? 425 ASN B C   1 
ATOM   4501 O  O   . ASN B 2 255 ? -25.149 4.22    -23.564 1   25.45  ? 425 ASN B O   1 
ATOM   4502 C  CB  . ASN B 2 255 ? -24.238 6.504   -25.244 1   25.61  ? 425 ASN B CB  1 
ATOM   4503 C  CG  . ASN B 2 255 ? -23.346 7.522   -25.896 1   28.8   ? 425 ASN B CG  1 
ATOM   4504 O  OD1 . ASN B 2 255 ? -23.012 7.379   -27.077 1   33.2   ? 425 ASN B OD1 1 
ATOM   4505 N  ND2 . ASN B 2 255 ? -22.969 8.558   -25.161 1   28.74  ? 425 ASN B ND2 1 
ATOM   4506 N  N   . PRO B 2 256 ? -25.6   5.94    -22.18  1   25.9   ? 426 PRO B N   1 
ATOM   4507 C  CA  . PRO B 2 256 ? -26.764 5.271   -21.598 1   25.64  ? 426 PRO B CA  1 
ATOM   4508 C  C   . PRO B 2 256 ? -27.887 5.191   -22.625 1   28.94  ? 426 PRO B C   1 
ATOM   4509 O  O   . PRO B 2 256 ? -28.017 6.073   -23.484 1   29.47  ? 426 PRO B O   1 
ATOM   4510 C  CB  . PRO B 2 256 ? -27.154 6.176   -20.427 1   24.95  ? 426 PRO B CB  1 
ATOM   4511 C  CG  . PRO B 2 256 ? -26.596 7.524   -20.781 1   23.42  ? 426 PRO B CG  1 
ATOM   4512 C  CD  . PRO B 2 256 ? -25.316 7.24    -21.546 1   23.99  ? 426 PRO B CD  1 
ATOM   4513 N  N   . PRO B 2 257 ? -28.766 4.167   -22.516 1   29.61  ? 427 PRO B N   1 
ATOM   4514 C  CA  . PRO B 2 257 ? -29.947 4.058   -23.384 1   28.62  ? 427 PRO B CA  1 
ATOM   4515 C  C   . PRO B 2 257 ? -30.952 5.126   -22.985 1   27.85  ? 427 PRO B C   1 
ATOM   4516 O  O   . PRO B 2 257 ? -31.099 5.391   -21.804 1   28.74  ? 427 PRO B O   1 
ATOM   4517 C  CB  . PRO B 2 257 ? -30.496 2.648   -23.075 1   27.04  ? 427 PRO B CB  1 
ATOM   4518 C  CG  . PRO B 2 257 ? -30.019 2.361   -21.665 1   26.92  ? 427 PRO B CG  1 
ATOM   4519 C  CD  . PRO B 2 257 ? -28.68  3.085   -21.518 1   27.79  ? 427 PRO B CD  1 
ATOM   4520 N  N   . GLU B 2 258 ? -31.645 5.71    -23.962 1   31.36  ? 428 GLU B N   1 
ATOM   4521 C  CA  . GLU B 2 258 ? -32.654 6.722   -23.687 1   35.91  ? 428 GLU B CA  1 
ATOM   4522 C  C   . GLU B 2 258 ? -33.913 6.111   -23.064 1   35.18  ? 428 GLU B C   1 
ATOM   4523 O  O   . GLU B 2 258 ? -34.649 6.833   -22.396 1   33.71  ? 428 GLU B O   1 
ATOM   4524 C  CB  . GLU B 2 258 ? -33.017 7.515   -24.94  1   39.9   ? 428 GLU B CB  1 
ATOM   4525 C  CG  . GLU B 2 258 ? -31.889 8.385   -25.49  1   52.34  ? 428 GLU B CG  1 
ATOM   4526 C  CD  . GLU B 2 258 ? -31.995 8.66    -26.996 1   72.06  ? 428 GLU B CD  1 
ATOM   4527 O  OE1 . GLU B 2 258 ? -32.982 8.194   -27.616 1   75.89  ? 428 GLU B OE1 1 
ATOM   4528 O  OE2 . GLU B 2 258 ? -31.095 9.323   -27.577 1   79.9   ? 428 GLU B OE2 1 
ATOM   4529 N  N   . THR B 2 259 ? -34.178 4.813   -23.307 1   34.49  ? 429 THR B N   1 
ATOM   4530 C  CA  . THR B 2 259 ? -35.298 4.109   -22.679 1   34.69  ? 429 THR B CA  1 
ATOM   4531 C  C   . THR B 2 259 ? -34.9   2.685   -22.304 1   32.1   ? 429 THR B C   1 
ATOM   4532 O  O   . THR B 2 259 ? -33.993 2.121   -22.898 1   33.77  ? 429 THR B O   1 
ATOM   4533 C  CB  . THR B 2 259 ? -36.547 4.05    -23.569 1   32.89  ? 429 THR B CB  1 
ATOM   4534 O  OG1 . THR B 2 259 ? -36.229 3.291   -24.731 1   30.96  ? 429 THR B OG1 1 
ATOM   4535 C  CG2 . THR B 2 259 ? -37.033 5.418   -23.99  1   32.72  ? 429 THR B CG2 1 
ATOM   4536 N  N   . LEU B 2 260 ? -35.609 2.112   -21.33  1   34.03  ? 430 LEU B N   1 
ATOM   4537 C  CA  . LEU B 2 260 ? -35.313 0.724   -20.894 1   40.86  ? 430 LEU B CA  1 
ATOM   4538 C  C   . LEU B 2 260 ? -36.115 -0.261  -21.757 1   46.18  ? 430 LEU B C   1 
ATOM   4539 O  O   . LEU B 2 260 ? -35.642 -1.4    -21.941 1   41.99  ? 430 LEU B O   1 
ATOM   4540 C  CB  . LEU B 2 260 ? -35.656 0.591   -19.412 1   38.27  ? 430 LEU B CB  1 
ATOM   4541 C  CG  . LEU B 2 260 ? -34.793 1.429   -18.464 1   36.3   ? 430 LEU B CG  1 
ATOM   4542 C  CD1 . LEU B 2 260 ? -35.096 1.125   -17.008 1   37.65  ? 430 LEU B CD1 1 
ATOM   4543 C  CD2 . LEU B 2 260 ? -33.333 1.169   -18.776 1   33.84  ? 430 LEU B CD2 1 
ATOM   4544 N  N   . ASN B 2 261 ? -37.272 0.17    -22.27  1   54.37  ? 431 ASN B N   1 
ATOM   4545 C  CA  . ASN B 2 261 ? -38.142 -0.733  -23.077 1   64.41  ? 431 ASN B CA  1 
ATOM   4546 C  C   . ASN B 2 261 ? -38.289 -2.072  -22.345 1   62.35  ? 431 ASN B C   1 
ATOM   4547 O  O   . ASN B 2 261 ? -37.994 -3.107  -22.983 1   55.48  ? 431 ASN B O   1 
ATOM   4548 C  CB  . ASN B 2 261 ? -37.611 -0.919  -24.494 1   68.61  ? 431 ASN B CB  1 
ATOM   4549 C  CG  . ASN B 2 261 ? -36.997 0.346   -25.042 1   77.34  ? 431 ASN B CG  1 
ATOM   4550 O  OD1 . ASN B 2 261 ? -35.783 0.549   -24.929 1   83.91  ? 431 ASN B OD1 1 
ATOM   4551 N  ND2 . ASN B 2 261 ? -37.813 1.208   -25.629 1   71.02  ? 431 ASN B ND2 1 
ATOM   4552 N  N   . SER C 1 4   ? -14.829 4.356   28.931  1   36.39  ? 0   SER C N   1 
ATOM   4553 C  CA  . SER C 1 4   ? -16.32  4.327   29      1   44.83  ? 0   SER C CA  1 
ATOM   4554 C  C   . SER C 1 4   ? -16.899 5.703   28.638  1   41.01  ? 0   SER C C   1 
ATOM   4555 O  O   . SER C 1 4   ? -17.658 5.886   27.678  1   35.1   ? 0   SER C O   1 
ATOM   4556 C  CB  . SER C 1 4   ? -16.788 3.871   30.392  1   44.82  ? 0   SER C CB  1 
ATOM   4557 O  OG  . SER C 1 4   ? -16.514 2.5     30.663  1   44.69  ? 0   SER C OG  1 
ATOM   4558 N  N   . MET C 1 5   ? -16.49  6.687   29.437  1   39.13  ? 1   MET C N   1 
ATOM   4559 C  CA  . MET C 1 5   ? -16.927 8.063   29.294  1   39.57  ? 1   MET C CA  1 
ATOM   4560 C  C   . MET C 1 5   ? -15.796 8.941   28.758  1   35.47  ? 1   MET C C   1 
ATOM   4561 O  O   . MET C 1 5   ? -15.88  10.165  28.816  1   34.09  ? 1   MET C O   1 
ATOM   4562 C  CB  . MET C 1 5   ? -17.421 8.568   30.658  1   38.51  ? 1   MET C CB  1 
ATOM   4563 C  CG  . MET C 1 5   ? -18.417 7.63    31.3    1   31.86  ? 1   MET C CG  1 
ATOM   4564 S  SD  . MET C 1 5   ? -19.957 7.635   30.364  1   37.21  ? 1   MET C SD  1 
ATOM   4565 C  CE  . MET C 1 5   ? -20.42  9.353   30.632  1   35.37  ? 1   MET C CE  1 
ATOM   4566 N  N   . GLU C 1 6   ? -14.757 8.294   28.218  1   35.55  ? 2   GLU C N   1 
ATOM   4567 C  CA  . GLU C 1 6   ? -13.556 8.971   27.781  1   37.36  ? 2   GLU C CA  1 
ATOM   4568 C  C   . GLU C 1 6   ? -13.901 9.855   26.59   1   33.1   ? 2   GLU C C   1 
ATOM   4569 O  O   . GLU C 1 6   ? -13.193 10.816  26.342  1   35.17  ? 2   GLU C O   1 
ATOM   4570 C  CB  . GLU C 1 6   ? -12.426 8.001   27.421  1   48.38  ? 2   GLU C CB  1 
ATOM   4571 C  CG  . GLU C 1 6   ? -11.12  8.696   27.025  1   63.48  ? 2   GLU C CG  1 
ATOM   4572 C  CD  . GLU C 1 6   ? -10.356 9.528   28.05   1   73.46  ? 2   GLU C CD  1 
ATOM   4573 O  OE1 . GLU C 1 6   ? -10.673 9.43    29.258  1   81.7   ? 2   GLU C OE1 1 
ATOM   4574 O  OE2 . GLU C 1 6   ? -9.431  10.272  27.65   1   68.31  ? 2   GLU C OE2 1 
ATOM   4575 N  N   . ASN C 1 7   ? -14.984 9.525   25.877  1   31.09  ? 3   ASN C N   1 
ATOM   4576 C  CA  . ASN C 1 7   ? -15.407 10.295  24.718  1   30.31  ? 3   ASN C CA  1 
ATOM   4577 C  C   . ASN C 1 7   ? -16.422 11.372  25.077  1   27.58  ? 3   ASN C C   1 
ATOM   4578 O  O   . ASN C 1 7   ? -16.925 12.052  24.177  1   27.16  ? 3   ASN C O   1 
ATOM   4579 C  CB  . ASN C 1 7   ? -16.051 9.419   23.656  1   32.88  ? 3   ASN C CB  1 
ATOM   4580 C  CG  . ASN C 1 7   ? -15.025 8.521   23.03   1   34.83  ? 3   ASN C CG  1 
ATOM   4581 O  OD1 . ASN C 1 7   ? -13.852 8.909   22.905  1   33.01  ? 3   ASN C OD1 1 
ATOM   4582 N  ND2 . ASN C 1 7   ? -15.453 7.308   22.71   1   35.18  ? 3   ASN C ND2 1 
ATOM   4583 N  N   . PHE C 1 8   ? -16.707 11.528  26.376  1   23.9   ? 4   PHE C N   1 
ATOM   4584 C  CA  . PHE C 1 8   ? -17.636 12.551  26.808  1   21.88  ? 4   PHE C CA  1 
ATOM   4585 C  C   . PHE C 1 8   ? -16.871 13.608  27.587  1   24.01  ? 4   PHE C C   1 
ATOM   4586 O  O   . PHE C 1 8   ? -16.14  13.274  28.514  1   27.65  ? 4   PHE C O   1 
ATOM   4587 C  CB  . PHE C 1 8   ? -18.781 11.899  27.578  1   20.87  ? 4   PHE C CB  1 
ATOM   4588 C  CG  . PHE C 1 8   ? -19.736 11.159  26.662  1   20.85  ? 4   PHE C CG  1 
ATOM   4589 C  CD1 . PHE C 1 8   ? -20.456 11.855  25.697  1   20.93  ? 4   PHE C CD1 1 
ATOM   4590 C  CD2 . PHE C 1 8   ? -19.909 9.783   26.765  1   21.1   ? 4   PHE C CD2 1 
ATOM   4591 C  CE1 . PHE C 1 8   ? -21.327 11.198  24.847  1   21.41  ? 4   PHE C CE1 1 
ATOM   4592 C  CE2 . PHE C 1 8   ? -20.773 9.131   25.901  1   21.34  ? 4   PHE C CE2 1 
ATOM   4593 C  CZ  . PHE C 1 8   ? -21.502 9.837   24.961  1   21.95  ? 4   PHE C CZ  1 
ATOM   4594 N  N   . GLN C 1 9   ? -17.02  14.871  27.16   1   26.36  ? 5   GLN C N   1 
ATOM   4595 C  CA  . GLN C 1 9   ? -16.568 16.053  27.889  1   24.02  ? 5   GLN C CA  1 
ATOM   4596 C  C   . GLN C 1 9   ? -17.755 16.692  28.613  1   23.07  ? 5   GLN C C   1 
ATOM   4597 O  O   . GLN C 1 9   ? -18.739 17.067  27.98   1   20.34  ? 5   GLN C O   1 
ATOM   4598 C  CB  . GLN C 1 9   ? -15.942 17.033  26.902  1   24.68  ? 5   GLN C CB  1 
ATOM   4599 C  CG  . GLN C 1 9   ? -15.485 18.319  27.577  1   32.74  ? 5   GLN C CG  1 
ATOM   4600 C  CD  . GLN C 1 9   ? -14.246 18.129  28.434  1   38.31  ? 5   GLN C CD  1 
ATOM   4601 O  OE1 . GLN C 1 9   ? -13.126 17.973  27.928  1   38.59  ? 5   GLN C OE1 1 
ATOM   4602 N  NE2 . GLN C 1 9   ? -14.439 18.124  29.748  1   36.53  ? 5   GLN C NE2 1 
ATOM   4603 N  N   . LYS C 1 10  ? -17.677 16.786  29.951  1   27.06  ? 6   LYS C N   1 
ATOM   4604 C  CA  . LYS C 1 10  ? -18.682 17.496  30.74   1   28.35  ? 6   LYS C CA  1 
ATOM   4605 C  C   . LYS C 1 10  ? -18.669 18.973  30.346  1   29.17  ? 6   LYS C C   1 
ATOM   4606 O  O   . LYS C 1 10  ? -17.61  19.553  30.102  1   28.98  ? 6   LYS C O   1 
ATOM   4607 C  CB  . LYS C 1 10  ? -18.45  17.345  32.249  1   30.85  ? 6   LYS C CB  1 
ATOM   4608 C  CG  . LYS C 1 10  ? -19.253 16.268  32.978  1   38.62  ? 6   LYS C CG  1 
ATOM   4609 C  CD  . LYS C 1 10  ? -19.061 14.82   32.515  1   46.01  ? 6   LYS C CD  1 
ATOM   4610 C  CE  . LYS C 1 10  ? -19.502 13.756  33.496  1   48.35  ? 6   LYS C CE  1 
ATOM   4611 N  NZ  . LYS C 1 10  ? -18.989 12.437  33.104  1   46.84  ? 6   LYS C NZ  1 
ATOM   4612 N  N   . VAL C 1 11  ? -19.859 19.561  30.217  1   27.29  ? 7   VAL C N   1 
ATOM   4613 C  CA  . VAL C 1 11  ? -19.947 20.976  29.894  1   27.32  ? 7   VAL C CA  1 
ATOM   4614 C  C   . VAL C 1 11  ? -20.527 21.731  31.095  1   26.85  ? 7   VAL C C   1 
ATOM   4615 O  O   . VAL C 1 11  ? -19.959 22.707  31.531  1   27.49  ? 7   VAL C O   1 
ATOM   4616 C  CB  . VAL C 1 11  ? -20.717 21.192  28.576  1   26.41  ? 7   VAL C CB  1 
ATOM   4617 C  CG1 . VAL C 1 11  ? -20.966 22.661  28.27   1   24.93  ? 7   VAL C CG1 1 
ATOM   4618 C  CG2 . VAL C 1 11  ? -19.992 20.523  27.414  1   26.12  ? 7   VAL C CG2 1 
ATOM   4619 N  N   . GLU C 1 12  ? -21.624 21.254  31.676  1   30.33  ? 8   GLU C N   1 
ATOM   4620 C  CA  . GLU C 1 12  ? -22.143 21.856  32.894  1   34.71  ? 8   GLU C CA  1 
ATOM   4621 C  C   . GLU C 1 12  ? -23.157 20.921  33.555  1   37.99  ? 8   GLU C C   1 
ATOM   4622 O  O   . GLU C 1 12  ? -23.689 20.023  32.896  1   39.89  ? 8   GLU C O   1 
ATOM   4623 C  CB  . GLU C 1 12  ? -22.762 23.219  32.584  1   36.48  ? 8   GLU C CB  1 
ATOM   4624 C  CG  . GLU C 1 12  ? -24.155 23.125  31.976  1   40.17  ? 8   GLU C CG  1 
ATOM   4625 C  CD  . GLU C 1 12  ? -24.601 24.422  31.333  1   44.25  ? 8   GLU C CD  1 
ATOM   4626 O  OE1 . GLU C 1 12  ? -23.934 24.849  30.353  1   45.07  ? 8   GLU C OE1 1 
ATOM   4627 O  OE2 . GLU C 1 12  ? -25.598 24.992  31.823  1   43.39  ? 8   GLU C OE2 1 
ATOM   4628 N  N   . LYS C 1 13  ? -23.388 21.131  34.862  1   38.88  ? 9   LYS C N   1 
ATOM   4629 C  CA  . LYS C 1 13  ? -24.425 20.425  35.601  1   45.85  ? 9   LYS C CA  1 
ATOM   4630 C  C   . LYS C 1 13  ? -25.762 21.081  35.244  1   45.86  ? 9   LYS C C   1 
ATOM   4631 O  O   . LYS C 1 13  ? -25.821 22.302  35.18   1   50.59  ? 9   LYS C O   1 
ATOM   4632 C  CB  . LYS C 1 13  ? -24.107 20.499  37.102  1   51.35  ? 9   LYS C CB  1 
ATOM   4633 C  CG  . LYS C 1 13  ? -24.824 19.465  37.972  1   63.79  ? 9   LYS C CG  1 
ATOM   4634 C  CD  . LYS C 1 13  ? -25.555 19.975  39.213  1   78.34  ? 9   LYS C CD  1 
ATOM   4635 C  CE  . LYS C 1 13  ? -26.78  20.786  38.861  1   90.95  ? 9   LYS C CE  1 
ATOM   4636 N  NZ  . LYS C 1 13  ? -27.956 20.52   39.702  1   94.12  ? 9   LYS C NZ  1 
ATOM   4637 N  N   . ILE C 1 14  ? -26.815 20.297  34.953  1   41.08  ? 10  ILE C N   1 
ATOM   4638 C  CA  . ILE C 1 14  ? -28.082 20.883  34.521  1   43.96  ? 10  ILE C CA  1 
ATOM   4639 C  C   . ILE C 1 14  ? -29.241 20.395  35.388  1   50.25  ? 10  ILE C C   1 
ATOM   4640 O  O   . ILE C 1 14  ? -30.388 20.783  35.159  1   55.05  ? 10  ILE C O   1 
ATOM   4641 C  CB  . ILE C 1 14  ? -28.409 20.654  33.025  1   40.35  ? 10  ILE C CB  1 
ATOM   4642 C  CG1 . ILE C 1 14  ? -28.78  19.202  32.713  1   37.93  ? 10  ILE C CG1 1 
ATOM   4643 C  CG2 . ILE C 1 14  ? -27.316 21.185  32.101  1   42.29  ? 10  ILE C CG2 1 
ATOM   4644 C  CD1 . ILE C 1 14  ? -28.785 18.863  31.234  1   36.29  ? 10  ILE C CD1 1 
ATOM   4645 N  N   . GLY C 1 15  ? -28.969 19.532  36.364  1   48.63  ? 11  GLY C N   1 
ATOM   4646 C  CA  . GLY C 1 15  ? -30.09  18.94   37.069  1   53.85  ? 11  GLY C CA  1 
ATOM   4647 C  C   . GLY C 1 15  ? -29.637 17.95   38.129  1   65.57  ? 11  GLY C C   1 
ATOM   4648 O  O   . GLY C 1 15  ? -28.447 17.655  38.254  1   67.91  ? 11  GLY C O   1 
ATOM   4649 N  N   . GLU C 1 16  ? -30.62  17.48   38.903  1   71.11  ? 12  GLU C N   1 
ATOM   4650 C  CA  . GLU C 1 16  ? -30.381 16.545  39.985  1   73.53  ? 12  GLU C CA  1 
ATOM   4651 C  C   . GLU C 1 16  ? -31.635 15.695  40.16   1   85.77  ? 12  GLU C C   1 
ATOM   4652 O  O   . GLU C 1 16  ? -32.727 16.094  39.755  1   80.82  ? 12  GLU C O   1 
ATOM   4653 C  CB  . GLU C 1 16  ? -30.045 17.311  41.262  1   65.83  ? 12  GLU C CB  1 
ATOM   4654 C  CG  . GLU C 1 16  ? -29.294 16.492  42.309  1   73.89  ? 12  GLU C CG  1 
ATOM   4655 C  CD  . GLU C 1 16  ? -27.832 16.86   42.54   1   83.94  ? 12  GLU C CD  1 
ATOM   4656 O  OE1 . GLU C 1 16  ? -27.265 16.385  43.549  1   74.02  ? 12  GLU C OE1 1 
ATOM   4657 O  OE2 . GLU C 1 16  ? -27.25  17.619  41.728  1   94.42  ? 12  GLU C OE2 1 
ATOM   4658 N  N   . GLY C 1 17  ? -31.426 14.541  40.797  1   99.41  ? 13  GLY C N   1 
ATOM   4659 C  CA  . GLY C 1 17  ? -32.525 13.628  41.134  1   95.96  ? 13  GLY C CA  1 
ATOM   4660 C  C   . GLY C 1 17  ? -32.11  12.901  42.399  1   97.72  ? 13  GLY C C   1 
ATOM   4661 O  O   . GLY C 1 17  ? -31.01  13.192  42.908  1   85.64  ? 13  GLY C O   1 
ATOM   4662 N  N   . THR C 1 18  ? -32.941 11.988  42.893  1   105.03 ? 14  THR C N   1 
ATOM   4663 C  CA  . THR C 1 18  ? -32.639 11.298  44.157  1   105.2  ? 14  THR C CA  1 
ATOM   4664 C  C   . THR C 1 18  ? -31.548 10.284  43.924  1   99.34  ? 14  THR C C   1 
ATOM   4665 O  O   . THR C 1 18  ? -30.866 9.938   44.901  1   91.55  ? 14  THR C O   1 
ATOM   4666 C  CB  . THR C 1 18  ? -33.923 10.662  44.681  1   107.16 ? 14  THR C CB  1 
ATOM   4667 O  OG1 . THR C 1 18  ? -34.36  9.766   43.664  1   103.48 ? 14  THR C OG1 1 
ATOM   4668 C  CG2 . THR C 1 18  ? -35.004 11.688  44.965  1   106.28 ? 14  THR C CG2 1 
ATOM   4669 N  N   . TYR C 1 19  ? -31.378 9.821   42.683  1   108.61 ? 15  TYR C N   1 
ATOM   4670 C  CA  . TYR C 1 19  ? -30.389 8.741   42.401  1   105.2  ? 15  TYR C CA  1 
ATOM   4671 C  C   . TYR C 1 19  ? -29.266 9.268   41.516  1   91.5   ? 15  TYR C C   1 
ATOM   4672 O  O   . TYR C 1 19  ? -28.46  8.443   41.052  1   82.82  ? 15  TYR C O   1 
ATOM   4673 C  CB  . TYR C 1 19  ? -31.055 7.506   41.786  1   106.54 ? 15  TYR C CB  1 
ATOM   4674 C  CG  . TYR C 1 19  ? -32.373 7.11    42.437  1   107.84 ? 15  TYR C CG  1 
ATOM   4675 C  CD1 . TYR C 1 19  ? -32.403 6.27    43.542  1   99.5   ? 15  TYR C CD1 1 
ATOM   4676 C  CD2 . TYR C 1 19  ? -33.584 7.584   41.95   1   105.41 ? 15  TYR C CD2 1 
ATOM   4677 C  CE1 . TYR C 1 19  ? -33.597 5.912   44.143  1   89.92  ? 15  TYR C CE1 1 
ATOM   4678 C  CE2 . TYR C 1 19  ? -34.784 7.238   42.546  1   101.95 ? 15  TYR C CE2 1 
ATOM   4679 C  CZ  . TYR C 1 19  ? -34.791 6.398   43.644  1   99.85  ? 15  TYR C CZ  1 
ATOM   4680 O  OH  . TYR C 1 19  ? -35.975 6.052   44.224  1   96.75  ? 15  TYR C OH  1 
ATOM   4681 N  N   . GLY C 1 20  ? -29.201 10.587  41.296  1   84.9   ? 16  GLY C N   1 
ATOM   4682 C  CA  . GLY C 1 20  ? -28.041 11.102  40.547  1   70.08  ? 16  GLY C CA  1 
ATOM   4683 C  C   . GLY C 1 20  ? -28.13  12.513  40.009  1   63.39  ? 16  GLY C C   1 
ATOM   4684 O  O   . GLY C 1 20  ? -29.152 13.183  40.239  1   57.02  ? 16  GLY C O   1 
ATOM   4685 N  N   . VAL C 1 21  ? -27.083 12.936  39.304  1   53.94  ? 17  VAL C N   1 
ATOM   4686 C  CA  . VAL C 1 21  ? -26.989 14.267  38.726  1   49.33  ? 17  VAL C CA  1 
ATOM   4687 C  C   . VAL C 1 21  ? -27.11  14.179  37.2    1   43.13  ? 17  VAL C C   1 
ATOM   4688 O  O   . VAL C 1 21  ? -26.899 13.115  36.634  1   40.44  ? 17  VAL C O   1 
ATOM   4689 C  CB  . VAL C 1 21  ? -25.685 14.944  39.19   1   49.42  ? 17  VAL C CB  1 
ATOM   4690 C  CG1 . VAL C 1 21  ? -25.465 16.301  38.52   1   51.94  ? 17  VAL C CG1 1 
ATOM   4691 C  CG2 . VAL C 1 21  ? -25.608 15.048  40.706  1   48.29  ? 17  VAL C CG2 1 
ATOM   4692 N  N   . VAL C 1 22  ? -27.516 15.286  36.559  1   36.61  ? 18  VAL C N   1 
ATOM   4693 C  CA  . VAL C 1 22  ? -27.691 15.354  35.114  1   32.67  ? 18  VAL C CA  1 
ATOM   4694 C  C   . VAL C 1 22  ? -26.725 16.405  34.581  1   32.17  ? 18  VAL C C   1 
ATOM   4695 O  O   . VAL C 1 22  ? -26.724 17.545  35.047  1   32.35  ? 18  VAL C O   1 
ATOM   4696 C  CB  . VAL C 1 22  ? -29.13  15.664  34.65   1   31.96  ? 18  VAL C CB  1 
ATOM   4697 C  CG1 . VAL C 1 22  ? -29.268 15.63   33.135  1   27.3   ? 18  VAL C CG1 1 
ATOM   4698 C  CG2 . VAL C 1 22  ? -30.154 14.722  35.262  1   33.69  ? 18  VAL C CG2 1 
ATOM   4699 N  N   . TYR C 1 23  ? -25.899 15.996  33.612  1   31.57  ? 19  TYR C N   1 
ATOM   4700 C  CA  . TYR C 1 23  ? -24.923 16.887  33.01   1   29.81  ? 19  TYR C CA  1 
ATOM   4701 C  C   . TYR C 1 23  ? -25.287 17.113  31.55   1   25.13  ? 19  TYR C C   1 
ATOM   4702 O  O   . TYR C 1 23  ? -25.843 16.235  30.904  1   23.2   ? 19  TYR C O   1 
ATOM   4703 C  CB  . TYR C 1 23  ? -23.522 16.274  33.008  1   32.32  ? 19  TYR C CB  1 
ATOM   4704 C  CG  . TYR C 1 23  ? -22.97  15.939  34.38   1   39.11  ? 19  TYR C CG  1 
ATOM   4705 C  CD1 . TYR C 1 23  ? -22.42  16.94   35.182  1   43.44  ? 19  TYR C CD1 1 
ATOM   4706 C  CD2 . TYR C 1 23  ? -22.969 14.63   34.856  1   43.51  ? 19  TYR C CD2 1 
ATOM   4707 C  CE1 . TYR C 1 23  ? -21.903 16.652  36.436  1   45.3   ? 19  TYR C CE1 1 
ATOM   4708 C  CE2 . TYR C 1 23  ? -22.457 14.331  36.11   1   50.63  ? 19  TYR C CE2 1 
ATOM   4709 C  CZ  . TYR C 1 23  ? -21.927 15.346  36.898  1   51.32  ? 19  TYR C CZ  1 
ATOM   4710 O  OH  . TYR C 1 23  ? -21.407 15.082  38.131  1   58.52  ? 19  TYR C OH  1 
ATOM   4711 N  N   . LYS C 1 24  ? -24.955 18.297  31.043  1   23.18  ? 20  LYS C N   1 
ATOM   4712 C  CA  . LYS C 1 24  ? -24.855 18.481  29.611  1   21.1   ? 20  LYS C CA  1 
ATOM   4713 C  C   . LYS C 1 24  ? -23.424 18.109  29.234  1   19.95  ? 20  LYS C C   1 
ATOM   4714 O  O   . LYS C 1 24  ? -22.478 18.491  29.929  1   18.84  ? 20  LYS C O   1 
ATOM   4715 C  CB  . LYS C 1 24  ? -25.196 19.934  29.27   1   21.84  ? 20  LYS C CB  1 
ATOM   4716 C  CG  . LYS C 1 24  ? -25.037 20.321  27.81   1   23.26  ? 20  LYS C CG  1 
ATOM   4717 C  CD  . LYS C 1 24  ? -24.742 21.803  27.635  1   24.62  ? 20  LYS C CD  1 
ATOM   4718 C  CE  . LYS C 1 24  ? -25.445 22.371  26.44   1   27.52  ? 20  LYS C CE  1 
ATOM   4719 N  NZ  . LYS C 1 24  ? -24.717 23.483  25.813  1   29.93  ? 20  LYS C NZ  1 
ATOM   4720 N  N   . ALA C 1 25  ? -23.282 17.34   28.147  1   18.02  ? 21  ALA C N   1 
ATOM   4721 C  CA  . ALA C 1 25  ? -21.969 16.867  27.745  1   19.1   ? 21  ALA C CA  1 
ATOM   4722 C  C   . ALA C 1 25  ? -21.832 16.918  26.231  1   19.96  ? 21  ALA C C   1 
ATOM   4723 O  O   . ALA C 1 25  ? -22.825 17.054  25.513  1   19.84  ? 21  ALA C O   1 
ATOM   4724 C  CB  . ALA C 1 25  ? -21.752 15.463  28.246  1   18.45  ? 21  ALA C CB  1 
ATOM   4725 N  N   . ARG C 1 26  ? -20.591 16.773  25.774  1   20.21  ? 22  ARG C N   1 
ATOM   4726 C  CA  . ARG C 1 26  ? -20.291 16.791  24.36   1   23.53  ? 22  ARG C CA  1 
ATOM   4727 C  C   . ARG C 1 26  ? -19.537 15.513  24.023  1   25.55  ? 22  ARG C C   1 
ATOM   4728 O  O   . ARG C 1 26  ? -18.519 15.191  24.651  1   28.05  ? 22  ARG C O   1 
ATOM   4729 C  CB  . ARG C 1 26  ? -19.384 17.981  24.039  1   28.62  ? 22  ARG C CB  1 
ATOM   4730 C  CG  . ARG C 1 26  ? -19.282 18.323  22.561  1   37.5   ? 22  ARG C CG  1 
ATOM   4731 C  CD  . ARG C 1 26  ? -18.308 19.468  22.288  1   46.87  ? 22  ARG C CD  1 
ATOM   4732 N  NE  . ARG C 1 26  ? -16.942 18.954  22.108  1   59.27  ? 22  ARG C NE  1 
ATOM   4733 C  CZ  . ARG C 1 26  ? -15.837 19.231  22.824  1   59.53  ? 22  ARG C CZ  1 
ATOM   4734 N  NH1 . ARG C 1 26  ? -15.891 20.059  23.857  1   53.07  ? 22  ARG C NH1 1 
ATOM   4735 N  NH2 . ARG C 1 26  ? -14.68  18.664  22.505  1   55.83  ? 22  ARG C NH2 1 
ATOM   4736 N  N   . ASN C 1 27  ? -20.03  14.798  23.006  1   22.56  ? 23  ASN C N   1 
ATOM   4737 C  CA  . ASN C 1 27  ? -19.262 13.702  22.453  1   19.7   ? 23  ASN C CA  1 
ATOM   4738 C  C   . ASN C 1 27  ? -18.066 14.271  21.706  1   18.87  ? 23  ASN C C   1 
ATOM   4739 O  O   . ASN C 1 27  ? -18.235 14.892  20.671  1   18.23  ? 23  ASN C O   1 
ATOM   4740 C  CB  . ASN C 1 27  ? -20.111 12.887  21.491  1   20.54  ? 23  ASN C CB  1 
ATOM   4741 C  CG  . ASN C 1 27  ? -19.424 11.618  21.037  1   20.32  ? 23  ASN C CG  1 
ATOM   4742 O  OD1 . ASN C 1 27  ? -18.27  11.641  20.564  1   18.51  ? 23  ASN C OD1 1 
ATOM   4743 N  ND2 . ASN C 1 27  ? -20.148 10.513  21.172  1   18.76  ? 23  ASN C ND2 1 
ATOM   4744 N  N   . LYS C 1 28  ? -16.863 13.973  22.192  1   21.35  ? 24  LYS C N   1 
ATOM   4745 C  CA  . LYS C 1 28  ? -15.637 14.583  21.691  1   24.92  ? 24  LYS C CA  1 
ATOM   4746 C  C   . LYS C 1 28  ? -15.325 14.162  20.253  1   23.2   ? 24  LYS C C   1 
ATOM   4747 O  O   . LYS C 1 28  ? -14.526 14.826  19.579  1   24.47  ? 24  LYS C O   1 
ATOM   4748 C  CB  . LYS C 1 28  ? -14.389 14.241  22.515  1   28.67  ? 24  LYS C CB  1 
ATOM   4749 C  CG  . LYS C 1 28  ? -14.505 14.255  24.024  1   35.11  ? 24  LYS C CG  1 
ATOM   4750 C  CD  . LYS C 1 28  ? -13.237 14.803  24.667  1   41.84  ? 24  LYS C CD  1 
ATOM   4751 C  CE  . LYS C 1 28  ? -13.038 14.39   26.103  1   46.19  ? 24  LYS C CE  1 
ATOM   4752 N  NZ  . LYS C 1 28  ? -12.16  13.233  26.281  1   44.82  ? 24  LYS C NZ  1 
ATOM   4753 N  N   . LEU C 1 29  ? -15.928 13.064  19.791  1   19.65  ? 25  LEU C N   1 
ATOM   4754 C  CA  . LEU C 1 29  ? -15.561 12.545  18.489  1   18.55  ? 25  LEU C CA  1 
ATOM   4755 C  C   . LEU C 1 29  ? -16.575 12.936  17.419  1   20.03  ? 25  LEU C C   1 
ATOM   4756 O  O   . LEU C 1 29  ? -16.152 13.195  16.298  1   21.13  ? 25  LEU C O   1 
ATOM   4757 C  CB  . LEU C 1 29  ? -15.38  11.038  18.585  1   17.33  ? 25  LEU C CB  1 
ATOM   4758 C  CG  . LEU C 1 29  ? -13.982 10.594  19.014  1   15.89  ? 25  LEU C CG  1 
ATOM   4759 C  CD1 . LEU C 1 29  ? -14.001 9.129   19.377  1   14.83  ? 25  LEU C CD1 1 
ATOM   4760 C  CD2 . LEU C 1 29  ? -12.986 10.887  17.919  1   14.75  ? 25  LEU C CD2 1 
ATOM   4761 N  N   . THR C 1 30  ? -17.882 12.954  17.761  1   19.79  ? 26  THR C N   1 
ATOM   4762 C  CA  . THR C 1 30  ? -18.955 13.212  16.802  1   19.82  ? 26  THR C CA  1 
ATOM   4763 C  C   . THR C 1 30  ? -19.455 14.657  16.879  1   21.27  ? 26  THR C C   1 
ATOM   4764 O  O   . THR C 1 30  ? -20.14  15.122  15.952  1   20.59  ? 26  THR C O   1 
ATOM   4765 C  CB  . THR C 1 30  ? -20.152 12.292  17.007  1   20.09  ? 26  THR C CB  1 
ATOM   4766 O  OG1 . THR C 1 30  ? -20.7   12.682  18.259  1   22.11  ? 26  THR C OG1 1 
ATOM   4767 C  CG2 . THR C 1 30  ? -19.806 10.818  16.999  1   19.87  ? 26  THR C CG2 1 
ATOM   4768 N  N   . GLY C 1 31  ? -19.194 15.324  18.024  1   20.3   ? 27  GLY C N   1 
ATOM   4769 C  CA  . GLY C 1 31  ? -19.633 16.691  18.263  1   17.27  ? 27  GLY C CA  1 
ATOM   4770 C  C   . GLY C 1 31  ? -21.022 16.755  18.898  1   18.51  ? 27  GLY C C   1 
ATOM   4771 O  O   . GLY C 1 31  ? -21.495 17.827  19.254  1   20.73  ? 27  GLY C O   1 
ATOM   4772 N  N   . GLU C 1 32  ? -21.693 15.614  19.058  1   18.46  ? 28  GLU C N   1 
ATOM   4773 C  CA  . GLU C 1 32  ? -23.054 15.639  19.567  1   18.24  ? 28  GLU C CA  1 
ATOM   4774 C  C   . GLU C 1 32  ? -23.007 16.116  21.014  1   19.04  ? 28  GLU C C   1 
ATOM   4775 O  O   . GLU C 1 32  ? -22.118 15.714  21.766  1   19.39  ? 28  GLU C O   1 
ATOM   4776 C  CB  . GLU C 1 32  ? -23.697 14.26   19.406  1   18.58  ? 28  GLU C CB  1 
ATOM   4777 C  CG  . GLU C 1 32  ? -25.112 14.178  19.958  1   19.24  ? 28  GLU C CG  1 
ATOM   4778 C  CD  . GLU C 1 32  ? -25.779 12.817  19.819  1   25.39  ? 28  GLU C CD  1 
ATOM   4779 O  OE1 . GLU C 1 32  ? -25.055 11.777  19.895  1   25.11  ? 28  GLU C OE1 1 
ATOM   4780 O  OE2 . GLU C 1 32  ? -27.054 12.807  19.676  1   29.09  ? 28  GLU C OE2 1 
ATOM   4781 N  N   . VAL C 1 33  ? -23.929 17.029  21.35   1   18.3   ? 29  VAL C N   1 
ATOM   4782 C  CA  . VAL C 1 33  ? -24.192 17.482  22.707  1   17.16  ? 29  VAL C CA  1 
ATOM   4783 C  C   . VAL C 1 33  ? -25.311 16.615  23.285  1   17.43  ? 29  VAL C C   1 
ATOM   4784 O  O   . VAL C 1 33  ? -26.337 16.432  22.648  1   19.34  ? 29  VAL C O   1 
ATOM   4785 C  CB  . VAL C 1 33  ? -24.607 18.966  22.711  1   16.11  ? 29  VAL C CB  1 
ATOM   4786 C  CG1 . VAL C 1 33  ? -24.933 19.45   24.121  1   15.62  ? 29  VAL C CG1 1 
ATOM   4787 C  CG2 . VAL C 1 33  ? -23.588 19.863  22.027  1   13.37  ? 29  VAL C CG2 1 
ATOM   4788 N  N   . VAL C 1 34  ? -25.128 16.133  24.513  1   15.93  ? 30  VAL C N   1 
ATOM   4789 C  CA  . VAL C 1 34  ? -26.021 15.15   25.098  1   16.58  ? 30  VAL C CA  1 
ATOM   4790 C  C   . VAL C 1 34  ? -26.284 15.538  26.553  1   18.8   ? 30  VAL C C   1 
ATOM   4791 O  O   . VAL C 1 34  ? -25.6   16.404  27.115  1   19.18  ? 30  VAL C O   1 
ATOM   4792 C  CB  . VAL C 1 34  ? -25.428 13.719  25.017  1   15.17  ? 30  VAL C CB  1 
ATOM   4793 C  CG1 . VAL C 1 34  ? -25.17  13.314  23.58   1   14.3   ? 30  VAL C CG1 1 
ATOM   4794 C  CG2 . VAL C 1 34  ? -24.157 13.542  25.854  1   13.24  ? 30  VAL C CG2 1 
ATOM   4795 N  N   . ALA C 1 35  ? -27.262 14.862  27.163  1   18.7   ? 31  ALA C N   1 
ATOM   4796 C  CA  . ALA C 1 35  ? -27.415 14.906  28.603  1   20.56  ? 31  ALA C CA  1 
ATOM   4797 C  C   . ALA C 1 35  ? -26.987 13.557  29.168  1   23.05  ? 31  ALA C C   1 
ATOM   4798 O  O   . ALA C 1 35  ? -27.347 12.515  28.626  1   26.19  ? 31  ALA C O   1 
ATOM   4799 C  CB  . ALA C 1 35  ? -28.851 15.209  28.939  1   18.83  ? 31  ALA C CB  1 
ATOM   4800 N  N   . LEU C 1 36  ? -26.182 13.575  30.226  1   24.78  ? 32  LEU C N   1 
ATOM   4801 C  CA  . LEU C 1 36  ? -25.813 12.348  30.918  1   27.04  ? 32  LEU C CA  1 
ATOM   4802 C  C   . LEU C 1 36  ? -26.534 12.311  32.26   1   27.25  ? 32  LEU C C   1 
ATOM   4803 O  O   . LEU C 1 36  ? -26.303 13.176  33.1    1   30.86  ? 32  LEU C O   1 
ATOM   4804 C  CB  . LEU C 1 36  ? -24.298 12.263  31.1    1   27.19  ? 32  LEU C CB  1 
ATOM   4805 C  CG  . LEU C 1 36  ? -23.483 12.392  29.815  1   29.81  ? 32  LEU C CG  1 
ATOM   4806 C  CD1 . LEU C 1 36  ? -22.003 12.373  30.161  1   31.75  ? 32  LEU C CD1 1 
ATOM   4807 C  CD2 . LEU C 1 36  ? -23.84  11.249  28.885  1   30.96  ? 32  LEU C CD2 1 
ATOM   4808 N  N   . LYS C 1 37  ? -27.459 11.365  32.409  1   25.37  ? 33  LYS C N   1 
ATOM   4809 C  CA  . LYS C 1 37  ? -28.021 11.031  33.704  1   26.51  ? 33  LYS C CA  1 
ATOM   4810 C  C   . LYS C 1 37  ? -27.088 9.995   34.336  1   25.85  ? 33  LYS C C   1 
ATOM   4811 O  O   . LYS C 1 37  ? -26.949 8.891   33.824  1   25.87  ? 33  LYS C O   1 
ATOM   4812 C  CB  . LYS C 1 37  ? -29.465 10.55   33.499  1   26.61  ? 33  LYS C CB  1 
ATOM   4813 C  CG  . LYS C 1 37  ? -30.337 10.628  34.735  1   29.2   ? 33  LYS C CG  1 
ATOM   4814 C  CD  . LYS C 1 37  ? -31.8   10.196  34.661  1   32.52  ? 33  LYS C CD  1 
ATOM   4815 C  CE  . LYS C 1 37  ? -32.603 11.033  33.696  1   35.63  ? 33  LYS C CE  1 
ATOM   4816 N  NZ  . LYS C 1 37  ? -34.052 10.859  33.857  1   34.51  ? 33  LYS C NZ  1 
ATOM   4817 N  N   . LYS C 1 38  ? -26.395 10.38   35.409  1   25.7   ? 34  LYS C N   1 
ATOM   4818 C  CA  . LYS C 1 38  ? -25.555 9.473   36.175  1   28.02  ? 34  LYS C CA  1 
ATOM   4819 C  C   . LYS C 1 38  ? -26.375 8.877   37.318  1   28.74  ? 34  LYS C C   1 
ATOM   4820 O  O   . LYS C 1 38  ? -26.884 9.615   38.155  1   29.19  ? 34  LYS C O   1 
ATOM   4821 C  CB  . LYS C 1 38  ? -24.371 10.242  36.765  1   30.99  ? 34  LYS C CB  1 
ATOM   4822 C  CG  . LYS C 1 38  ? -23.424 9.443   37.664  1   35.08  ? 34  LYS C CG  1 
ATOM   4823 C  CD  . LYS C 1 38  ? -22.217 10.223  38.192  1   36.97  ? 34  LYS C CD  1 
ATOM   4824 C  CE  . LYS C 1 38  ? -22.383 10.792  39.571  1   41.68  ? 34  LYS C CE  1 
ATOM   4825 N  NZ  . LYS C 1 38  ? -21.102 11.159  40.194  1   40.55  ? 34  LYS C NZ  1 
ATOM   4826 N  N   . ILE C 1 39  ? -26.507 7.541   37.343  1   30.41  ? 35  ILE C N   1 
ATOM   4827 C  CA  . ILE C 1 39  ? -27.262 6.852   38.381  1   30.54  ? 35  ILE C CA  1 
ATOM   4828 C  C   . ILE C 1 39  ? -26.283 6.028   39.206  1   32.21  ? 35  ILE C C   1 
ATOM   4829 O  O   . ILE C 1 39  ? -25.681 5.118   38.66   1   33.07  ? 35  ILE C O   1 
ATOM   4830 C  CB  . ILE C 1 39  ? -28.392 6.008   37.766  1   29.27  ? 35  ILE C CB  1 
ATOM   4831 C  CG1 . ILE C 1 39  ? -29.532 6.885   37.281  1   29.84  ? 35  ILE C CG1 1 
ATOM   4832 C  CG2 . ILE C 1 39  ? -28.917 5.001   38.78   1   28.26  ? 35  ILE C CG2 1 
ATOM   4833 C  CD1 . ILE C 1 39  ? -30.176 6.37    36.02   1   32.49  ? 35  ILE C CD1 1 
ATOM   4834 N  N   . ARG C 1 40  ? -26.153 6.373   40.481  1   39.3   ? 36  ARG C N   1 
ATOM   4835 C  CA  . ARG C 1 40  ? -25.234 5.633   41.373  1   46.65  ? 36  ARG C CA  1 
ATOM   4836 C  C   . ARG C 1 40  ? -25.846 4.279   41.724  1   45.28  ? 36  ARG C C   1 
ATOM   4837 O  O   . ARG C 1 40  ? -27.032 4.232   42.096  1   44.58  ? 36  ARG C O   1 
ATOM   4838 C  CB  . ARG C 1 40  ? -24.924 6.386   42.667  1   57.64  ? 36  ARG C CB  1 
ATOM   4839 C  CG  . ARG C 1 40  ? -23.888 5.689   43.534  1   73.78  ? 36  ARG C CG  1 
ATOM   4840 C  CD  . ARG C 1 40  ? -23.529 6.506   44.76   1   86.77  ? 36  ARG C CD  1 
ATOM   4841 N  NE  . ARG C 1 40  ? -22.547 5.819   45.605  1   97.28  ? 36  ARG C NE  1 
ATOM   4842 C  CZ  . ARG C 1 40  ? -21.238 5.839   45.398  1   97.01  ? 36  ARG C CZ  1 
ATOM   4843 N  NH1 . ARG C 1 40  ? -20.483 6.714   46.038  1   96.13  ? 36  ARG C NH1 1 
ATOM   4844 N  NH2 . ARG C 1 40  ? -20.69  4.988   44.55   1   92.51  ? 36  ARG C NH2 1 
ATOM   4845 N  N   . LEU C 1 41  ? -25.066 3.227   41.553  1   39.88  ? 37  LEU C N   1 
ATOM   4846 C  CA  . LEU C 1 41  ? -25.482 1.886   41.914  1   35.9   ? 37  LEU C CA  1 
ATOM   4847 C  C   . LEU C 1 41  ? -25.082 1.625   43.361  1   36.52  ? 37  LEU C C   1 
ATOM   4848 O  O   . LEU C 1 41  ? -23.961 1.927   43.782  1   38.33  ? 37  LEU C O   1 
ATOM   4849 C  CB  . LEU C 1 41  ? -24.831 0.885   40.968  1   31.26  ? 37  LEU C CB  1 
ATOM   4850 C  CG  . LEU C 1 41  ? -25.273 0.972   39.509  1   28.97  ? 37  LEU C CG  1 
ATOM   4851 C  CD1 . LEU C 1 41  ? -24.825 -0.243  38.723  1   25.78  ? 37  LEU C CD1 1 
ATOM   4852 C  CD2 . LEU C 1 41  ? -26.772 1.141   39.43   1   30.36  ? 37  LEU C CD2 1 
ATOM   4853 N  N   . ASP C 1 42  ? -26.026 1.06    44.107  1   35.64  ? 38  ASP C N   1 
ATOM   4854 C  CA  . ASP C 1 42  ? -25.779 0.687   45.489  1   37.88  ? 38  ASP C CA  1 
ATOM   4855 C  C   . ASP C 1 42  ? -25.307 -0.758  45.513  1   30.27  ? 38  ASP C C   1 
ATOM   4856 O  O   . ASP C 1 42  ? -26.099 -1.67   45.737  1   30.84  ? 38  ASP C O   1 
ATOM   4857 C  CB  . ASP C 1 42  ? -27.023 0.913   46.338  1   44.96  ? 38  ASP C CB  1 
ATOM   4858 C  CG  . ASP C 1 42  ? -27.485 2.359   46.384  1   48.11  ? 38  ASP C CG  1 
ATOM   4859 O  OD1 . ASP C 1 42  ? -26.612 3.221   46.647  1   51.03  ? 38  ASP C OD1 1 
ATOM   4860 O  OD2 . ASP C 1 42  ? -28.694 2.601   46.134  1   45.83  ? 38  ASP C OD2 1 
ATOM   4861 N  N   . THR C 1 43  ? -24.014 -0.945  45.271  1   24.51  ? 39  THR C N   1 
ATOM   4862 C  CA  . THR C 1 43  ? -23.487 -2.257  44.931  1   23.02  ? 39  THR C CA  1 
ATOM   4863 C  C   . THR C 1 43  ? -23.442 -3.187  46.149  1   22.39  ? 39  THR C C   1 
ATOM   4864 O  O   . THR C 1 43  ? -23.291 -4.402  45.996  1   23.04  ? 39  THR C O   1 
ATOM   4865 C  CB  . THR C 1 43  ? -22.111 -2.087  44.283  1   23.55  ? 39  THR C CB  1 
ATOM   4866 O  OG1 . THR C 1 43  ? -21.253 -1.426  45.212  1   25.34  ? 39  THR C OG1 1 
ATOM   4867 C  CG2 . THR C 1 43  ? -22.172 -1.252  43.016  1   23.76  ? 39  THR C CG2 1 
ATOM   4868 N  N   . GLU C 1 44  ? -23.533 -2.621  47.361  1   19.84  ? 40  GLU C N   1 
ATOM   4869 C  CA  . GLU C 1 44  ? -23.49  -3.442  48.555  1   18.58  ? 40  GLU C CA  1 
ATOM   4870 C  C   . GLU C 1 44  ? -24.867 -3.519  49.217  1   17.94  ? 40  GLU C C   1 
ATOM   4871 O  O   . GLU C 1 44  ? -25.022 -4.197  50.231  1   19.79  ? 40  GLU C O   1 
ATOM   4872 C  CB  . GLU C 1 44  ? -22.41  -2.972  49.534  1   18.95  ? 40  GLU C CB  1 
ATOM   4873 C  CG  . GLU C 1 44  ? -20.983 -3.153  49.025  1   19.07  ? 40  GLU C CG  1 
ATOM   4874 C  CD  . GLU C 1 44  ? -20.593 -2.254  47.859  1   18.81  ? 40  GLU C CD  1 
ATOM   4875 O  OE1 . GLU C 1 44  ? -20.026 -2.77   46.86   1   19.52  ? 40  GLU C OE1 1 
ATOM   4876 O  OE2 . GLU C 1 44  ? -20.86  -1.038  47.937  1   17.4   ? 40  GLU C OE2 1 
ATOM   4877 N  N   . THR C 1 45  ? -25.863 -2.824  48.67   1   16.48  ? 41  THR C N   1 
ATOM   4878 C  CA  . THR C 1 45  ? -27.115 -2.66   49.39   1   17.77  ? 41  THR C CA  1 
ATOM   4879 C  C   . THR C 1 45  ? -28.316 -2.974  48.5    1   19.33  ? 41  THR C C   1 
ATOM   4880 O  O   . THR C 1 45  ? -28.826 -4.078  48.582  1   22.75  ? 41  THR C O   1 
ATOM   4881 C  CB  . THR C 1 45  ? -27.22  -1.321  50.129  1   17.34  ? 41  THR C CB  1 
ATOM   4882 O  OG1 . THR C 1 45  ? -27.152 -0.242  49.199  1   18.67  ? 41  THR C OG1 1 
ATOM   4883 C  CG2 . THR C 1 45  ? -26.126 -1.136  51.161  1   16.46  ? 41  THR C CG2 1 
ATOM   4884 N  N   . GLU C 1 46  ? -28.758 -2.032  47.663  1   19.49  ? 42  GLU C N   1 
ATOM   4885 C  CA  . GLU C 1 46  ? -30.036 -2.145  46.982  1   22.53  ? 42  GLU C CA  1 
ATOM   4886 C  C   . GLU C 1 46  ? -29.906 -2.339  45.468  1   20.71  ? 42  GLU C C   1 
ATOM   4887 O  O   . GLU C 1 46  ? -30.908 -2.608  44.82   1   18.77  ? 42  GLU C O   1 
ATOM   4888 C  CB  . GLU C 1 46  ? -30.964 -0.984  47.356  1   27.4   ? 42  GLU C CB  1 
ATOM   4889 C  CG  . GLU C 1 46  ? -31.564 -1.134  48.758  1   37.73  ? 42  GLU C CG  1 
ATOM   4890 C  CD  . GLU C 1 46  ? -32.105 -2.501  49.218  1   46.37  ? 42  GLU C CD  1 
ATOM   4891 O  OE1 . GLU C 1 46  ? -33.031 -3.089  48.593  1   52.96  ? 42  GLU C OE1 1 
ATOM   4892 O  OE2 . GLU C 1 46  ? -31.618 -3.004  50.255  1   46.11  ? 42  GLU C OE2 1 
ATOM   4893 N  N   . GLY C 1 47  ? -28.702 -2.167  44.899  1   19.96  ? 43  GLY C N   1 
ATOM   4894 C  CA  . GLY C 1 47  ? -28.446 -2.514  43.509  1   18.14  ? 43  GLY C CA  1 
ATOM   4895 C  C   . GLY C 1 47  ? -28.978 -1.438  42.583  1   19.64  ? 43  GLY C C   1 
ATOM   4896 O  O   . GLY C 1 47  ? -28.888 -0.263  42.909  1   25.61  ? 43  GLY C O   1 
ATOM   4897 N  N   . VAL C 1 48  ? -29.537 -1.826  41.435  1   18.58  ? 44  VAL C N   1 
ATOM   4898 C  CA  . VAL C 1 48  ? -29.964 -0.846  40.45   1   17.02  ? 44  VAL C CA  1 
ATOM   4899 C  C   . VAL C 1 48  ? -31.35  -0.35   40.838  1   19.3   ? 44  VAL C C   1 
ATOM   4900 O  O   . VAL C 1 48  ? -32.284 -1.135  40.961  1   18.71  ? 44  VAL C O   1 
ATOM   4901 C  CB  . VAL C 1 48  ? -29.996 -1.422  39.026  1   14.75  ? 44  VAL C CB  1 
ATOM   4902 C  CG1 . VAL C 1 48  ? -30.418 -0.392  37.99   1   13.23  ? 44  VAL C CG1 1 
ATOM   4903 C  CG2 . VAL C 1 48  ? -28.661 -2.01   38.644  1   14.28  ? 44  VAL C CG2 1 
ATOM   4904 N  N   . PRO C 1 49  ? -31.541 0.974   41.012  1   22.77  ? 45  PRO C N   1 
ATOM   4905 C  CA  . PRO C 1 49  ? -32.831 1.505   41.449  1   22.01  ? 45  PRO C CA  1 
ATOM   4906 C  C   . PRO C 1 49  ? -33.941 1.12    40.474  1   23.59  ? 45  PRO C C   1 
ATOM   4907 O  O   . PRO C 1 49  ? -33.736 1.062   39.256  1   25.43  ? 45  PRO C O   1 
ATOM   4908 C  CB  . PRO C 1 49  ? -32.669 3.02    41.522  1   19.69  ? 45  PRO C CB  1 
ATOM   4909 C  CG  . PRO C 1 49  ? -31.276 3.33    41.017  1   20.93  ? 45  PRO C CG  1 
ATOM   4910 C  CD  . PRO C 1 49  ? -30.543 2.026   40.751  1   23.89  ? 45  PRO C CD  1 
ATOM   4911 N  N   . SER C 1 50  ? -35.131 0.914   41.03   1   21.6   ? 46  SER C N   1 
ATOM   4912 C  CA  . SER C 1 50  ? -36.243 0.504   40.208  1   23.12  ? 46  SER C CA  1 
ATOM   4913 C  C   . SER C 1 50  ? -36.665 1.61    39.232  1   23.82  ? 46  SER C C   1 
ATOM   4914 O  O   . SER C 1 50  ? -37.174 1.299   38.155  1   23.91  ? 46  SER C O   1 
ATOM   4915 C  CB  . SER C 1 50  ? -37.363 0.014   41.068  1   24.25  ? 46  SER C CB  1 
ATOM   4916 O  OG  . SER C 1 50  ? -37.788 1.03    41.961  1   30.43  ? 46  SER C OG  1 
ATOM   4917 N  N   . THR C 1 51  ? -36.46  2.894   39.58   1   25.76  ? 47  THR C N   1 
ATOM   4918 C  CA  . THR C 1 51  ? -36.891 3.971   38.68   1   27.26  ? 47  THR C CA  1 
ATOM   4919 C  C   . THR C 1 51  ? -36.062 3.917   37.412  1   25.63  ? 47  THR C C   1 
ATOM   4920 O  O   . THR C 1 51  ? -36.589 4.245   36.353  1   30.72  ? 47  THR C O   1 
ATOM   4921 C  CB  . THR C 1 51  ? -36.873 5.398   39.22   1   26.32  ? 47  THR C CB  1 
ATOM   4922 O  OG1 . THR C 1 51  ? -35.638 5.55    39.902  1   30.26  ? 47  THR C OG1 1 
ATOM   4923 C  CG2 . THR C 1 51  ? -37.97  5.651   40.234  1   32.73  ? 47  THR C CG2 1 
ATOM   4924 N  N   . ALA C 1 52  ? -34.803 3.476   37.551  1   20.36  ? 48  ALA C N   1 
ATOM   4925 C  CA  . ALA C 1 52  ? -33.901 3.409   36.423  1   18.91  ? 48  ALA C CA  1 
ATOM   4926 C  C   . ALA C 1 52  ? -34.24  2.216   35.537  1   20.38  ? 48  ALA C C   1 
ATOM   4927 O  O   . ALA C 1 52  ? -34.24  2.349   34.326  1   21.48  ? 48  ALA C O   1 
ATOM   4928 C  CB  . ALA C 1 52  ? -32.492 3.327   36.914  1   18.9   ? 48  ALA C CB  1 
ATOM   4929 N  N   . ILE C 1 53  ? -34.514 1.054   36.14   1   19.06  ? 49  ILE C N   1 
ATOM   4930 C  CA  . ILE C 1 53  ? -34.931 -0.127  35.411  1   19.74  ? 49  ILE C CA  1 
ATOM   4931 C  C   . ILE C 1 53  ? -36.159 0.186   34.549  1   22.6   ? 49  ILE C C   1 
ATOM   4932 O  O   . ILE C 1 53  ? -36.236 -0.2    33.374  1   22.66  ? 49  ILE C O   1 
ATOM   4933 C  CB  . ILE C 1 53  ? -35.209 -1.251  36.417  1   18.41  ? 49  ILE C CB  1 
ATOM   4934 C  CG1 . ILE C 1 53  ? -33.897 -1.786  36.975  1   17.21  ? 49  ILE C CG1 1 
ATOM   4935 C  CG2 . ILE C 1 53  ? -36.063 -2.35   35.79   1   17     ? 49  ILE C CG2 1 
ATOM   4936 C  CD1 . ILE C 1 53  ? -34.071 -2.596  38.239  1   16.37  ? 49  ILE C CD1 1 
ATOM   4937 N  N   . ARG C 1 54  ? -37.129 0.882   35.149  1   23.57  ? 50  ARG C N   1 
ATOM   4938 C  CA  . ARG C 1 54  ? -38.341 1.232   34.434  1   25.11  ? 50  ARG C CA  1 
ATOM   4939 C  C   . ARG C 1 54  ? -38.035 2.264   33.356  1   27.67  ? 50  ARG C C   1 
ATOM   4940 O  O   . ARG C 1 54  ? -38.458 2.094   32.221  1   30.98  ? 50  ARG C O   1 
ATOM   4941 C  CB  . ARG C 1 54  ? -39.422 1.731   35.396  1   26.52  ? 50  ARG C CB  1 
ATOM   4942 C  CG  . ARG C 1 54  ? -40.212 0.617   36.077  1   27.09  ? 50  ARG C CG  1 
ATOM   4943 C  CD  . ARG C 1 54  ? -41.329 1.221   36.902  1   24.9   ? 50  ARG C CD  1 
ATOM   4944 N  NE  . ARG C 1 54  ? -41.894 0.223   37.81   1   26.58  ? 50  ARG C NE  1 
ATOM   4945 C  CZ  . ARG C 1 54  ? -42.719 0.518   38.806  1   25.99  ? 50  ARG C CZ  1 
ATOM   4946 N  NH1 . ARG C 1 54  ? -43.006 1.775   39.096  1   26.53  ? 50  ARG C NH1 1 
ATOM   4947 N  NH2 . ARG C 1 54  ? -43.224 -0.448  39.535  1   23.65  ? 50  ARG C NH2 1 
ATOM   4948 N  N   . GLU C 1 55  ? -37.319 3.338   33.716  1   26.88  ? 51  GLU C N   1 
ATOM   4949 C  CA  . GLU C 1 55  ? -37.012 4.371   32.744  1   26.89  ? 51  GLU C CA  1 
ATOM   4950 C  C   . GLU C 1 55  ? -36.31  3.766   31.526  1   26.4   ? 51  GLU C C   1 
ATOM   4951 O  O   . GLU C 1 55  ? -36.694 4.035   30.396  1   28.29  ? 51  GLU C O   1 
ATOM   4952 C  CB  . GLU C 1 55  ? -36.19  5.498   33.362  1   26.78  ? 51  GLU C CB  1 
ATOM   4953 C  CG  . GLU C 1 55  ? -35.909 6.641   32.385  1   28.61  ? 51  GLU C CG  1 
ATOM   4954 C  CD  . GLU C 1 55  ? -35.338 7.899   33.026  1   29.57  ? 51  GLU C CD  1 
ATOM   4955 O  OE1 . GLU C 1 55  ? -35.016 7.909   34.242  1   28.81  ? 51  GLU C OE1 1 
ATOM   4956 O  OE2 . GLU C 1 55  ? -35.296 8.897   32.284  1   32.04  ? 51  GLU C OE2 1 
ATOM   4957 N  N   . ILE C 1 56  ? -35.285 2.952   31.758  1   24.48  ? 52  ILE C N   1 
ATOM   4958 C  CA  . ILE C 1 56  ? -34.465 2.444   30.675  1   25.45  ? 52  ILE C CA  1 
ATOM   4959 C  C   . ILE C 1 56  ? -35.299 1.497   29.8    1   28.56  ? 52  ILE C C   1 
ATOM   4960 O  O   . ILE C 1 56  ? -35.406 1.717   28.589  1   28.74  ? 52  ILE C O   1 
ATOM   4961 C  CB  . ILE C 1 56  ? -33.155 1.817   31.201  1   21.16  ? 52  ILE C CB  1 
ATOM   4962 C  CG1 . ILE C 1 56  ? -32.249 2.862   31.839  1   17.99  ? 52  ILE C CG1 1 
ATOM   4963 C  CG2 . ILE C 1 56  ? -32.428 1.123   30.055  1   21.63  ? 52  ILE C CG2 1 
ATOM   4964 C  CD1 . ILE C 1 56  ? -31.285 2.309   32.88   1   18.24  ? 52  ILE C CD1 1 
ATOM   4965 N  N   . SER C 1 57  ? -35.917 0.482   30.421  1   28.84  ? 53  SER C N   1 
ATOM   4966 C  CA  . SER C 1 57  ? -36.703 -0.518  29.709  1   29.13  ? 53  SER C CA  1 
ATOM   4967 C  C   . SER C 1 57  ? -37.808 0.13    28.876  1   29.93  ? 53  SER C C   1 
ATOM   4968 O  O   . SER C 1 57  ? -37.966 -0.21   27.698  1   35.12  ? 53  SER C O   1 
ATOM   4969 C  CB  . SER C 1 57  ? -37.26  -1.558  30.641  1   30.34  ? 53  SER C CB  1 
ATOM   4970 O  OG  . SER C 1 57  ? -38.018 -0.94   31.674  1   37.56  ? 53  SER C OG  1 
ATOM   4971 N  N   . LEU C 1 58  ? -38.546 1.081   29.464  1   26.07  ? 54  LEU C N   1 
ATOM   4972 C  CA  . LEU C 1 58  ? -39.69  1.673   28.78   1   27.25  ? 54  LEU C CA  1 
ATOM   4973 C  C   . LEU C 1 58  ? -39.253 2.577   27.628  1   28.84  ? 54  LEU C C   1 
ATOM   4974 O  O   . LEU C 1 58  ? -39.801 2.469   26.522  1   37.94  ? 54  LEU C O   1 
ATOM   4975 C  CB  . LEU C 1 58  ? -40.64  2.351   29.757  1   25.46  ? 54  LEU C CB  1 
ATOM   4976 C  CG  . LEU C 1 58  ? -41.116 1.415   30.874  1   27.15  ? 54  LEU C CG  1 
ATOM   4977 C  CD1 . LEU C 1 58  ? -41.941 2.146   31.928  1   26.12  ? 54  LEU C CD1 1 
ATOM   4978 C  CD2 . LEU C 1 58  ? -41.851 0.217   30.3    1   23.55  ? 54  LEU C CD2 1 
ATOM   4979 N  N   . LEU C 1 59  ? -38.201 3.366   27.851  1   25.37  ? 55  LEU C N   1 
ATOM   4980 C  CA  . LEU C 1 59  ? -37.67  4.242   26.817  1   28.24  ? 55  LEU C CA  1 
ATOM   4981 C  C   . LEU C 1 59  ? -37.039 3.457   25.661  1   30.49  ? 55  LEU C C   1 
ATOM   4982 O  O   . LEU C 1 59  ? -36.998 3.97    24.539  1   33.1   ? 55  LEU C O   1 
ATOM   4983 C  CB  . LEU C 1 59  ? -36.669 5.246   27.386  1   25.18  ? 55  LEU C CB  1 
ATOM   4984 C  CG  . LEU C 1 59  ? -37.255 6.444   28.126  1   27.19  ? 55  LEU C CG  1 
ATOM   4985 C  CD1 . LEU C 1 59  ? -36.111 7.226   28.746  1   27.62  ? 55  LEU C CD1 1 
ATOM   4986 C  CD2 . LEU C 1 59  ? -38.093 7.323   27.198  1   26.62  ? 55  LEU C CD2 1 
ATOM   4987 N  N   . LYS C 1 60  ? -36.505 2.26    25.941  1   29.7   ? 56  LYS C N   1 
ATOM   4988 C  CA  . LYS C 1 60  ? -35.856 1.44    24.927  1   38.57  ? 56  LYS C CA  1 
ATOM   4989 C  C   . LYS C 1 60  ? -36.87  1.003   23.861  1   41.23  ? 56  LYS C C   1 
ATOM   4990 O  O   . LYS C 1 60  ? -36.489 0.673   22.73   1   44.03  ? 56  LYS C O   1 
ATOM   4991 C  CB  . LYS C 1 60  ? -35.001 0.313   25.53   1   36.69  ? 56  LYS C CB  1 
ATOM   4992 C  CG  . LYS C 1 60  ? -33.516 0.628   25.58   1   38.95  ? 56  LYS C CG  1 
ATOM   4993 C  CD  . LYS C 1 60  ? -32.659 -0.272  26.459  1   46.86  ? 56  LYS C CD  1 
ATOM   4994 C  CE  . LYS C 1 60  ? -31.313 -0.514  25.773  1   52.62  ? 56  LYS C CE  1 
ATOM   4995 N  NZ  . LYS C 1 60  ? -30.067 -0.278  26.542  1   43.62  ? 56  LYS C NZ  1 
ATOM   4996 N  N   . GLU C 1 61  ? -38.162 1.046   24.205  1   39.46  ? 57  GLU C N   1 
ATOM   4997 C  CA  . GLU C 1 61  ? -39.18  0.597   23.268  1   44.23  ? 57  GLU C CA  1 
ATOM   4998 C  C   . GLU C 1 61  ? -40.16  1.721   22.902  1   45.59  ? 57  GLU C C   1 
ATOM   4999 O  O   . GLU C 1 61  ? -41.165 1.487   22.241  1   51.29  ? 57  GLU C O   1 
ATOM   5000 C  CB  . GLU C 1 61  ? -39.8   -0.72   23.754  1   46.58  ? 57  GLU C CB  1 
ATOM   5001 C  CG  . GLU C 1 61  ? -40.362 -0.677  25.175  1   46.3   ? 57  GLU C CG  1 
ATOM   5002 C  CD  . GLU C 1 61  ? -41.351 -1.837  25.296  1   42.06  ? 57  GLU C CD  1 
ATOM   5003 O  OE1 . GLU C 1 61  ? -42.562 -1.589  25.085  1   43.89  ? 57  GLU C OE1 1 
ATOM   5004 O  OE2 . GLU C 1 61  ? -40.948 -2.98   25.607  1   41.59  ? 57  GLU C OE2 1 
ATOM   5005 N  N   . LEU C 1 62  ? -39.864 2.954   23.311  1   41.55  ? 58  LEU C N   1 
ATOM   5006 C  CA  . LEU C 1 62  ? -40.693 4.092   22.962  1   35.95  ? 58  LEU C CA  1 
ATOM   5007 C  C   . LEU C 1 62  ? -39.894 5.005   22.032  1   34.84  ? 58  LEU C C   1 
ATOM   5008 O  O   . LEU C 1 62  ? -39.241 5.943   22.479  1   45.35  ? 58  LEU C O   1 
ATOM   5009 C  CB  . LEU C 1 62  ? -41.15  4.81    24.236  1   34.76  ? 58  LEU C CB  1 
ATOM   5010 C  CG  . LEU C 1 62  ? -42.259 4.139   25.048  1   35.64  ? 58  LEU C CG  1 
ATOM   5011 C  CD1 . LEU C 1 62  ? -42.345 4.724   26.451  1   36.02  ? 58  LEU C CD1 1 
ATOM   5012 C  CD2 . LEU C 1 62  ? -43.589 4.293   24.351  1   37.01  ? 58  LEU C CD2 1 
ATOM   5013 N  N   . ASN C 1 63  ? -39.955 4.725   20.731  1   33.45  ? 59  ASN C N   1 
ATOM   5014 C  CA  . ASN C 1 63  ? -39.219 5.478   19.73   1   35.5   ? 59  ASN C CA  1 
ATOM   5015 C  C   . ASN C 1 63  ? -40.226 6.3     18.941  1   31.24  ? 59  ASN C C   1 
ATOM   5016 O  O   . ASN C 1 63  ? -40.94  5.79    18.085  1   31.17  ? 59  ASN C O   1 
ATOM   5017 C  CB  . ASN C 1 63  ? -38.327 4.564   18.888  1   48.57  ? 59  ASN C CB  1 
ATOM   5018 C  CG  . ASN C 1 63  ? -37.566 3.569   19.748  1   73.06  ? 59  ASN C CG  1 
ATOM   5019 O  OD1 . ASN C 1 63  ? -37.898 2.373   19.769  1   85.94  ? 59  ASN C OD1 1 
ATOM   5020 N  ND2 . ASN C 1 63  ? -36.582 4.036   20.511  1   77     ? 59  ASN C ND2 1 
ATOM   5021 N  N   . HIS C 1 64  ? -40.31  7.582   19.273  1   30.02  ? 60  HIS C N   1 
ATOM   5022 C  CA  . HIS C 1 64  ? -41.257 8.468   18.619  1   31.96  ? 60  HIS C CA  1 
ATOM   5023 C  C   . HIS C 1 64  ? -40.65  9.865   18.618  1   32.21  ? 60  HIS C C   1 
ATOM   5024 O  O   . HIS C 1 64  ? -39.861 10.205  19.498  1   35.91  ? 60  HIS C O   1 
ATOM   5025 C  CB  . HIS C 1 64  ? -42.612 8.417   19.333  1   33.6   ? 60  HIS C CB  1 
ATOM   5026 C  CG  . HIS C 1 64  ? -43.663 9.302   18.744  1   35.28  ? 60  HIS C CG  1 
ATOM   5027 N  ND1 . HIS C 1 64  ? -43.755 10.651  19.026  1   32.25  ? 60  HIS C ND1 1 
ATOM   5028 C  CD2 . HIS C 1 64  ? -44.673 9.009   17.899  1   30.36  ? 60  HIS C CD2 1 
ATOM   5029 C  CE1 . HIS C 1 64  ? -44.78  11.146  18.352  1   31     ? 60  HIS C CE1 1 
ATOM   5030 N  NE2 . HIS C 1 64  ? -45.353 10.166  17.678  1   29.97  ? 60  HIS C NE2 1 
ATOM   5031 N  N   . PRO C 1 65  ? -40.938 10.688  17.595  1   28.91  ? 61  PRO C N   1 
ATOM   5032 C  CA  . PRO C 1 65  ? -40.34  12.017  17.512  1   27.31  ? 61  PRO C CA  1 
ATOM   5033 C  C   . PRO C 1 65  ? -40.671 12.955  18.664  1   28.25  ? 61  PRO C C   1 
ATOM   5034 O  O   . PRO C 1 65  ? -39.969 13.952  18.801  1   28.94  ? 61  PRO C O   1 
ATOM   5035 C  CB  . PRO C 1 65  ? -40.794 12.597  16.159  1   26.04  ? 61  PRO C CB  1 
ATOM   5036 C  CG  . PRO C 1 65  ? -41.892 11.673  15.679  1   25.8   ? 61  PRO C CG  1 
ATOM   5037 C  CD  . PRO C 1 65  ? -41.76  10.345  16.427  1   26.78  ? 61  PRO C CD  1 
ATOM   5038 N  N   . ASN C 1 66  ? -41.709 12.637  19.465  1   27.05  ? 62  ASN C N   1 
ATOM   5039 C  CA  . ASN C 1 66  ? -42.122 13.493  20.576  1   27.67  ? 62  ASN C CA  1 
ATOM   5040 C  C   . ASN C 1 66  ? -41.835 12.862  21.94   1   29.75  ? 62  ASN C C   1 
ATOM   5041 O  O   . ASN C 1 66  ? -42.382 13.289  22.954  1   30.23  ? 62  ASN C O   1 
ATOM   5042 C  CB  . ASN C 1 66  ? -43.584 13.892  20.451  1   25.97  ? 62  ASN C CB  1 
ATOM   5043 C  CG  . ASN C 1 66  ? -43.779 14.758  19.237  1   28.61  ? 62  ASN C CG  1 
ATOM   5044 O  OD1 . ASN C 1 66  ? -44.416 14.299  18.292  1   33.78  ? 62  ASN C OD1 1 
ATOM   5045 N  ND2 . ASN C 1 66  ? -43.206 15.957  19.201  1   25.26  ? 62  ASN C ND2 1 
ATOM   5046 N  N   . ILE C 1 67  ? -40.981 11.835  21.959  1   27.67  ? 63  ILE C N   1 
ATOM   5047 C  CA  . ILE C 1 67  ? -40.529 11.214  23.189  1   26.03  ? 63  ILE C CA  1 
ATOM   5048 C  C   . ILE C 1 67  ? -39.01  11.283  23.168  1   27.08  ? 63  ILE C C   1 
ATOM   5049 O  O   . ILE C 1 67  ? -38.399 10.966  22.145  1   27.42  ? 63  ILE C O   1 
ATOM   5050 C  CB  . ILE C 1 67  ? -41.023 9.76    23.282  1   23.33  ? 63  ILE C CB  1 
ATOM   5051 C  CG1 . ILE C 1 67  ? -42.551 9.687   23.263  1   20.06  ? 63  ILE C CG1 1 
ATOM   5052 C  CG2 . ILE C 1 67  ? -40.413 9.067   24.499  1   21.96  ? 63  ILE C CG2 1 
ATOM   5053 C  CD1 . ILE C 1 67  ? -43.102 8.278   23.276  1   17.5   ? 63  ILE C CD1 1 
ATOM   5054 N  N   . VAL C 1 68  ? -38.433 11.711  24.296  1   25.38  ? 64  VAL C N   1 
ATOM   5055 C  CA  . VAL C 1 68  ? -37.008 11.966  24.37   1   25.71  ? 64  VAL C CA  1 
ATOM   5056 C  C   . VAL C 1 68  ? -36.283 10.664  24.015  1   27.3   ? 64  VAL C C   1 
ATOM   5057 O  O   . VAL C 1 68  ? -36.699 9.58    24.424  1   22.54  ? 64  VAL C O   1 
ATOM   5058 C  CB  . VAL C 1 68  ? -36.61  12.502  25.767  1   24.92  ? 64  VAL C CB  1 
ATOM   5059 C  CG1 . VAL C 1 68  ? -36.801 11.452  26.867  1   18.81  ? 64  VAL C CG1 1 
ATOM   5060 C  CG2 . VAL C 1 68  ? -35.187 13.055  25.788  1   20.8   ? 64  VAL C CG2 1 
ATOM   5061 N  N   . LYS C 1 69  ? -35.185 10.798  23.258  1   29.23  ? 65  LYS C N   1 
ATOM   5062 C  CA  . LYS C 1 69  ? -34.401 9.658   22.819  1   32.05  ? 65  LYS C CA  1 
ATOM   5063 C  C   . LYS C 1 69  ? -33.365 9.322   23.886  1   32.3   ? 65  LYS C C   1 
ATOM   5064 O  O   . LYS C 1 69  ? -32.55  10.173  24.269  1   29.69  ? 65  LYS C O   1 
ATOM   5065 C  CB  . LYS C 1 69  ? -33.73  9.943   21.475  1   34.25  ? 65  LYS C CB  1 
ATOM   5066 C  CG  . LYS C 1 69  ? -34.261 9.154   20.3    1   50.88  ? 65  LYS C CG  1 
ATOM   5067 C  CD  . LYS C 1 69  ? -33.772 9.556   18.9    1   67.42  ? 65  LYS C CD  1 
ATOM   5068 C  CE  . LYS C 1 69  ? -34.512 10.627  18.112  1   67.55  ? 65  LYS C CE  1 
ATOM   5069 N  NZ  . LYS C 1 69  ? -33.917 11.965  18.227  1   74.25  ? 65  LYS C NZ  1 
ATOM   5070 N  N   . LEU C 1 70  ? -33.445 8.083   24.386  1   29.8   ? 66  LEU C N   1 
ATOM   5071 C  CA  . LEU C 1 70  ? -32.351 7.512   25.151  1   28.38  ? 66  LEU C CA  1 
ATOM   5072 C  C   . LEU C 1 70  ? -31.377 6.923   24.13   1   28.85  ? 66  LEU C C   1 
ATOM   5073 O  O   . LEU C 1 70  ? -31.765 6.048   23.375  1   31.64  ? 66  LEU C O   1 
ATOM   5074 C  CB  . LEU C 1 70  ? -32.918 6.449   26.096  1   24.34  ? 66  LEU C CB  1 
ATOM   5075 C  CG  . LEU C 1 70  ? -31.891 5.687   26.934  1   24.4   ? 66  LEU C CG  1 
ATOM   5076 C  CD1 . LEU C 1 70  ? -31.163 6.604   27.935  1   22.64  ? 66  LEU C CD1 1 
ATOM   5077 C  CD2 . LEU C 1 70  ? -32.554 4.532   27.64   1   25.37  ? 66  LEU C CD2 1 
ATOM   5078 N  N   . LEU C 1 71  ? -30.146 7.439   24.065  1   27.36  ? 67  LEU C N   1 
ATOM   5079 C  CA  . LEU C 1 71  ? -29.212 7.112   22.993  1   25.01  ? 67  LEU C CA  1 
ATOM   5080 C  C   . LEU C 1 71  ? -28.386 5.87    23.336  1   22.37  ? 67  LEU C C   1 
ATOM   5081 O  O   . LEU C 1 71  ? -28.093 5.04    22.465  1   21.13  ? 67  LEU C O   1 
ATOM   5082 C  CB  . LEU C 1 71  ? -28.298 8.323   22.774  1   22.81  ? 67  LEU C CB  1 
ATOM   5083 C  CG  . LEU C 1 71  ? -29.001 9.611   22.349  1   20.57  ? 67  LEU C CG  1 
ATOM   5084 C  CD1 . LEU C 1 71  ? -27.977 10.713  22.238  1   21.47  ? 67  LEU C CD1 1 
ATOM   5085 C  CD2 . LEU C 1 71  ? -29.763 9.509   21.03   1   18.71  ? 67  LEU C CD2 1 
ATOM   5086 N  N   . ASP C 1 72  ? -27.992 5.79    24.607  1   20.26  ? 68  ASP C N   1 
ATOM   5087 C  CA  . ASP C 1 72  ? -27.101 4.754   25.076  1   21.1   ? 68  ASP C CA  1 
ATOM   5088 C  C   . ASP C 1 72  ? -27.238 4.611   26.588  1   21.71  ? 68  ASP C C   1 
ATOM   5089 O  O   . ASP C 1 72  ? -27.756 5.487   27.271  1   22.85  ? 68  ASP C O   1 
ATOM   5090 C  CB  . ASP C 1 72  ? -25.662 5.086   24.719  1   21.23  ? 68  ASP C CB  1 
ATOM   5091 C  CG  . ASP C 1 72  ? -24.732 3.885   24.662  1   23.36  ? 68  ASP C CG  1 
ATOM   5092 O  OD1 . ASP C 1 72  ? -25.217 2.744   24.829  1   23.32  ? 68  ASP C OD1 1 
ATOM   5093 O  OD2 . ASP C 1 72  ? -23.531 4.098   24.453  1   26.15  ? 68  ASP C OD2 1 
ATOM   5094 N  N   . VAL C 1 73  ? -26.736 3.493   27.097  1   22.75  ? 69  VAL C N   1 
ATOM   5095 C  CA  . VAL C 1 73  ? -26.663 3.191   28.513  1   23.88  ? 69  VAL C CA  1 
ATOM   5096 C  C   . VAL C 1 73  ? -25.275 2.612   28.739  1   25.54  ? 69  VAL C C   1 
ATOM   5097 O  O   . VAL C 1 73  ? -24.976 1.519   28.264  1   28.8   ? 69  VAL C O   1 
ATOM   5098 C  CB  . VAL C 1 73  ? -27.749 2.187   28.958  1   21.33  ? 69  VAL C CB  1 
ATOM   5099 C  CG1 . VAL C 1 73  ? -27.646 1.836   30.433  1   21.57  ? 69  VAL C CG1 1 
ATOM   5100 C  CG2 . VAL C 1 73  ? -29.146 2.692   28.65   1   20.34  ? 69  VAL C CG2 1 
ATOM   5101 N  N   . ILE C 1 74  ? -24.445 3.364   29.463  1   26.55  ? 70  ILE C N   1 
ATOM   5102 C  CA  . ILE C 1 74  ? -23.065 2.982   29.701  1   28.41  ? 70  ILE C CA  1 
ATOM   5103 C  C   . ILE C 1 74  ? -22.942 2.466   31.124  1   29.66  ? 70  ILE C C   1 
ATOM   5104 O  O   . ILE C 1 74  ? -23.267 3.168   32.07   1   32.1   ? 70  ILE C O   1 
ATOM   5105 C  CB  . ILE C 1 74  ? -22.116 4.162   29.437  1   27.89  ? 70  ILE C CB  1 
ATOM   5106 C  CG1 . ILE C 1 74  ? -22.094 4.495   27.944  1   29.36  ? 70  ILE C CG1 1 
ATOM   5107 C  CG2 . ILE C 1 74  ? -20.718 3.862   29.984  1   25.16  ? 70  ILE C CG2 1 
ATOM   5108 C  CD1 . ILE C 1 74  ? -21.516 5.854   27.634  1   30.29  ? 70  ILE C CD1 1 
ATOM   5109 N  N   . HIS C 1 75  ? -22.42  1.247   31.247  1   36.11  ? 71  HIS C N   1 
ATOM   5110 C  CA  . HIS C 1 75  ? -22.292 0.562   32.525  1   38.08  ? 71  HIS C CA  1 
ATOM   5111 C  C   . HIS C 1 75  ? -20.87  0.699   33.053  1   38.38  ? 71  HIS C C   1 
ATOM   5112 O  O   . HIS C 1 75  ? -19.922 0.889   32.299  1   36.13  ? 71  HIS C O   1 
ATOM   5113 C  CB  . HIS C 1 75  ? -22.622 -0.927  32.375  1   35.42  ? 71  HIS C CB  1 
ATOM   5114 C  CG  . HIS C 1 75  ? -23.996 -1.214  31.85   1   34.64  ? 71  HIS C CG  1 
ATOM   5115 N  ND1 . HIS C 1 75  ? -24.966 -1.838  32.601  1   34.82  ? 71  HIS C ND1 1 
ATOM   5116 C  CD2 . HIS C 1 75  ? -24.537 -1.027  30.629  1   36.94  ? 71  HIS C CD2 1 
ATOM   5117 C  CE1 . HIS C 1 75  ? -26.064 -1.979  31.87   1   37.86  ? 71  HIS C CE1 1 
ATOM   5118 N  NE2 . HIS C 1 75  ? -25.824 -1.513  30.66   1   38.82  ? 71  HIS C NE2 1 
ATOM   5119 N  N   . THR C 1 76  ? -20.768 0.681   34.381  1   42.3   ? 72  THR C N   1 
ATOM   5120 C  CA  . THR C 1 76  ? -19.551 0.338   35.099  1   40.3   ? 72  THR C CA  1 
ATOM   5121 C  C   . THR C 1 76  ? -19.982 -0.652  36.175  1   36.66  ? 72  THR C C   1 
ATOM   5122 O  O   . THR C 1 76  ? -21.151 -1.045  36.203  1   30.41  ? 72  THR C O   1 
ATOM   5123 C  CB  . THR C 1 76  ? -18.805 1.563   35.647  1   38.69  ? 72  THR C CB  1 
ATOM   5124 O  OG1 . THR C 1 76  ? -19.622 2.318   36.54   1   41.77  ? 72  THR C OG1 1 
ATOM   5125 C  CG2 . THR C 1 76  ? -18.42  2.555   34.562  1   38.85  ? 72  THR C CG2 1 
ATOM   5126 N  N   . GLU C 1 77  ? -19.024 -1.079  37.003  1   38.55  ? 73  GLU C N   1 
ATOM   5127 C  CA  . GLU C 1 77  ? -19.344 -1.829  38.201  1   38.23  ? 73  GLU C CA  1 
ATOM   5128 C  C   . GLU C 1 77  ? -20.236 -0.948  39.08   1   34.82  ? 73  GLU C C   1 
ATOM   5129 O  O   . GLU C 1 77  ? -21.188 -1.457  39.665  1   34.41  ? 73  GLU C O   1 
ATOM   5130 C  CB  . GLU C 1 77  ? -18.065 -2.302  38.904  1   45.25  ? 73  GLU C CB  1 
ATOM   5131 C  CG  . GLU C 1 77  ? -18.32  -3.217  40.106  1   56.35  ? 73  GLU C CG  1 
ATOM   5132 C  CD  . GLU C 1 77  ? -17.185 -3.463  41.103  1   63     ? 73  GLU C CD  1 
ATOM   5133 O  OE1 . GLU C 1 77  ? -17.398 -3.222  42.327  1   59.82  ? 73  GLU C OE1 1 
ATOM   5134 O  OE2 . GLU C 1 77  ? -16.082 -3.879  40.658  1   57.15  ? 73  GLU C OE2 1 
ATOM   5135 N  N   . ASN C 1 78  ? -19.971 0.379   39.075  1   31.23  ? 74  ASN C N   1 
ATOM   5136 C  CA  . ASN C 1 78  ? -20.324 1.304   40.15   1   28.34  ? 74  ASN C CA  1 
ATOM   5137 C  C   . ASN C 1 78  ? -21.333 2.383   39.749  1   27.26  ? 74  ASN C C   1 
ATOM   5138 O  O   . ASN C 1 78  ? -22.086 2.848   40.598  1   25.68  ? 74  ASN C O   1 
ATOM   5139 C  CB  . ASN C 1 78  ? -19.075 1.903   40.788  1   30.44  ? 74  ASN C CB  1 
ATOM   5140 C  CG  . ASN C 1 78  ? -18.214 0.854   41.466  1   34.41  ? 74  ASN C CG  1 
ATOM   5141 O  OD1 . ASN C 1 78  ? -17.047 0.678   41.097  1   37.63  ? 74  ASN C OD1 1 
ATOM   5142 N  ND2 . ASN C 1 78  ? -18.753 0.138   42.446  1   31.16  ? 74  ASN C ND2 1 
ATOM   5143 N  N   . LYS C 1 79  ? -21.345 2.808   38.478  1   30.02  ? 75  LYS C N   1 
ATOM   5144 C  CA  . LYS C 1 79  ? -22.274 3.844   38.032  1   30.29  ? 75  LYS C CA  1 
ATOM   5145 C  C   . LYS C 1 79  ? -22.999 3.367   36.783  1   26.57  ? 75  LYS C C   1 
ATOM   5146 O  O   . LYS C 1 79  ? -22.471 2.596   35.994  1   28.51  ? 75  LYS C O   1 
ATOM   5147 C  CB  . LYS C 1 79  ? -21.617 5.166   37.612  1   34.29  ? 75  LYS C CB  1 
ATOM   5148 C  CG  . LYS C 1 79  ? -20.512 5.727   38.5    1   47.81  ? 75  LYS C CG  1 
ATOM   5149 C  CD  . LYS C 1 79  ? -20.996 6.649   39.615  1   64.17  ? 75  LYS C CD  1 
ATOM   5150 C  CE  . LYS C 1 79  ? -19.93  7.101   40.589  1   70.42  ? 75  LYS C CE  1 
ATOM   5151 N  NZ  . LYS C 1 79  ? -20.478 8.002   41.613  1   70.83  ? 75  LYS C NZ  1 
ATOM   5152 N  N   . LEU C 1 80  ? -24.212 3.87    36.599  1   25.15  ? 76  LEU C N   1 
ATOM   5153 C  CA  . LEU C 1 80  ? -24.896 3.787   35.319  1   26.26  ? 76  LEU C CA  1 
ATOM   5154 C  C   . LEU C 1 80  ? -24.954 5.185   34.685  1   26.58  ? 76  LEU C C   1 
ATOM   5155 O  O   . LEU C 1 80  ? -25.354 6.146   35.34   1   26.53  ? 76  LEU C O   1 
ATOM   5156 C  CB  . LEU C 1 80  ? -26.281 3.271   35.69   1   26.53  ? 76  LEU C CB  1 
ATOM   5157 C  CG  . LEU C 1 80  ? -26.933 2.294   34.718  1   27.38  ? 76  LEU C CG  1 
ATOM   5158 C  CD1 . LEU C 1 80  ? -25.985 1.109   34.47   1   28.95  ? 76  LEU C CD1 1 
ATOM   5159 C  CD2 . LEU C 1 80  ? -28.254 1.867   35.341  1   23.44  ? 76  LEU C CD2 1 
ATOM   5160 N  N   . TYR C 1 81  ? -24.491 5.323   33.437  1   24.49  ? 77  TYR C N   1 
ATOM   5161 C  CA  . TYR C 1 81  ? -24.607 6.583   32.727  1   25.7   ? 77  TYR C CA  1 
ATOM   5162 C  C   . TYR C 1 81  ? -25.645 6.431   31.621  1   26.29  ? 77  TYR C C   1 
ATOM   5163 O  O   . TYR C 1 81  ? -25.463 5.6     30.735  1   28.39  ? 77  TYR C O   1 
ATOM   5164 C  CB  . TYR C 1 81  ? -23.257 6.996   32.136  1   27.26  ? 77  TYR C CB  1 
ATOM   5165 C  CG  . TYR C 1 81  ? -22.28  7.565   33.147  1   29.27  ? 77  TYR C CG  1 
ATOM   5166 C  CD1 . TYR C 1 81  ? -22.448 8.85    33.648  1   30.77  ? 77  TYR C CD1 1 
ATOM   5167 C  CD2 . TYR C 1 81  ? -21.203 6.812   33.608  1   32.71  ? 77  TYR C CD2 1 
ATOM   5168 C  CE1 . TYR C 1 81  ? -21.571 9.371   34.587  1   36.15  ? 77  TYR C CE1 1 
ATOM   5169 C  CE2 . TYR C 1 81  ? -20.311 7.325   34.541  1   35.5   ? 77  TYR C CE2 1 
ATOM   5170 C  CZ  . TYR C 1 81  ? -20.489 8.615   35.019  1   39.53  ? 77  TYR C CZ  1 
ATOM   5171 O  OH  . TYR C 1 81  ? -19.604 9.152   35.92   1   48.25  ? 77  TYR C OH  1 
ATOM   5172 N  N   . LEU C 1 82  ? -26.739 7.204   31.7    1   22.96  ? 78  LEU C N   1 
ATOM   5173 C  CA  . LEU C 1 82  ? -27.723 7.243   30.629  1   21.87  ? 78  LEU C CA  1 
ATOM   5174 C  C   . LEU C 1 82  ? -27.358 8.376   29.685  1   22     ? 78  LEU C C   1 
ATOM   5175 O  O   . LEU C 1 82  ? -27.232 9.497   30.134  1   22.08  ? 78  LEU C O   1 
ATOM   5176 C  CB  . LEU C 1 82  ? -29.148 7.456   31.131  1   21.24  ? 78  LEU C CB  1 
ATOM   5177 C  CG  . LEU C 1 82  ? -29.661 6.593   32.287  1   23.03  ? 78  LEU C CG  1 
ATOM   5178 C  CD1 . LEU C 1 82  ? -31.103 6.202   32.061  1   20.78  ? 78  LEU C CD1 1 
ATOM   5179 C  CD2 . LEU C 1 82  ? -28.804 5.382   32.623  1   24.87  ? 78  LEU C CD2 1 
ATOM   5180 N  N   . VAL C 1 83  ? -27.233 8.094   28.383  1   23.37  ? 79  VAL C N   1 
ATOM   5181 C  CA  . VAL C 1 83  ? -26.954 9.149   27.413  1   21.27  ? 79  VAL C CA  1 
ATOM   5182 C  C   . VAL C 1 83  ? -28.26  9.48    26.693  1   22.09  ? 79  VAL C C   1 
ATOM   5183 O  O   . VAL C 1 83  ? -28.845 8.621   26.031  1   23.65  ? 79  VAL C O   1 
ATOM   5184 C  CB  . VAL C 1 83  ? -25.836 8.711   26.442  1   19.48  ? 79  VAL C CB  1 
ATOM   5185 C  CG1 . VAL C 1 83  ? -25.349 9.848   25.544  1   17.25  ? 79  VAL C CG1 1 
ATOM   5186 C  CG2 . VAL C 1 83  ? -24.659 8.107   27.2    1   17.76  ? 79  VAL C CG2 1 
ATOM   5187 N  N   . PHE C 1 84  ? -28.754 10.707  26.909  1   21.11  ? 80  PHE C N   1 
ATOM   5188 C  CA  . PHE C 1 84  ? -29.972 11.207  26.271  1   20.12  ? 80  PHE C CA  1 
ATOM   5189 C  C   . PHE C 1 84  ? -29.625 12.274  25.24   1   20.14  ? 80  PHE C C   1 
ATOM   5190 O  O   . PHE C 1 84  ? -28.622 12.98   25.388  1   22.02  ? 80  PHE C O   1 
ATOM   5191 C  CB  . PHE C 1 84  ? -30.891 11.94   27.244  1   18.34  ? 80  PHE C CB  1 
ATOM   5192 C  CG  . PHE C 1 84  ? -31.597 10.996  28.185  1   18.98  ? 80  PHE C CG  1 
ATOM   5193 C  CD1 . PHE C 1 84  ? -30.983 10.563  29.35   1   19.8   ? 80  PHE C CD1 1 
ATOM   5194 C  CD2 . PHE C 1 84  ? -32.873 10.549  27.889  1   21.52  ? 80  PHE C CD2 1 
ATOM   5195 C  CE1 . PHE C 1 84  ? -31.646 9.702   30.212  1   21.8   ? 80  PHE C CE1 1 
ATOM   5196 C  CE2 . PHE C 1 84  ? -33.521 9.667   28.74   1   23.85  ? 80  PHE C CE2 1 
ATOM   5197 C  CZ  . PHE C 1 84  ? -32.906 9.245   29.902  1   23.35  ? 80  PHE C CZ  1 
ATOM   5198 N  N   . GLU C 1 85  ? -30.475 12.404  24.217  1   19.74  ? 81  GLU C N   1 
ATOM   5199 C  CA  . GLU C 1 85  ? -30.373 13.573  23.369  1   22.43  ? 81  GLU C CA  1 
ATOM   5200 C  C   . GLU C 1 85  ? -30.463 14.81   24.269  1   25.35  ? 81  GLU C C   1 
ATOM   5201 O  O   . GLU C 1 85  ? -30.982 14.732  25.392  1   26.49  ? 81  GLU C O   1 
ATOM   5202 C  CB  . GLU C 1 85  ? -31.42  13.477  22.267  1   22.31  ? 81  GLU C CB  1 
ATOM   5203 C  CG  . GLU C 1 85  ? -32.843 13.746  22.726  1   26.02  ? 81  GLU C CG  1 
ATOM   5204 C  CD  . GLU C 1 85  ? -33.828 13.778  21.565  1   32.67  ? 81  GLU C CD  1 
ATOM   5205 O  OE1 . GLU C 1 85  ? -33.569 14.471  20.557  1   37.51  ? 81  GLU C OE1 1 
ATOM   5206 O  OE2 . GLU C 1 85  ? -34.869 13.1    21.675  1   35.57  ? 81  GLU C OE2 1 
ATOM   5207 N  N   . PHE C 1 86  ? -29.88  15.924  23.812  1   25.52  ? 82  PHE C N   1 
ATOM   5208 C  CA  . PHE C 1 86  ? -30.009 17.207  24.493  1   26.37  ? 82  PHE C CA  1 
ATOM   5209 C  C   . PHE C 1 86  ? -30.785 18.137  23.584  1   28.73  ? 82  PHE C C   1 
ATOM   5210 O  O   . PHE C 1 86  ? -30.435 18.27   22.419  1   32.48  ? 82  PHE C O   1 
ATOM   5211 C  CB  . PHE C 1 86  ? -28.663 17.908  24.667  1   27.96  ? 82  PHE C CB  1 
ATOM   5212 C  CG  . PHE C 1 86  ? -28.764 19.27   25.341  1   31.68  ? 82  PHE C CG  1 
ATOM   5213 C  CD1 . PHE C 1 86  ? -28.946 19.371  26.723  1   32.46  ? 82  PHE C CD1 1 
ATOM   5214 C  CD2 . PHE C 1 86  ? -28.693 20.452  24.591  1   34.12  ? 82  PHE C CD2 1 
ATOM   5215 C  CE1 . PHE C 1 86  ? -29.038 20.62   27.335  1   32.32  ? 82  PHE C CE1 1 
ATOM   5216 C  CE2 . PHE C 1 86  ? -28.788 21.696  25.203  1   34.52  ? 82  PHE C CE2 1 
ATOM   5217 C  CZ  . PHE C 1 86  ? -28.949 21.778  26.577  1   34.64  ? 82  PHE C CZ  1 
ATOM   5218 N  N   . LEU C 1 87  ? -31.829 18.782  24.095  1   34.55  ? 83  LEU C N   1 
ATOM   5219 C  CA  . LEU C 1 87  ? -32.647 19.571  23.188  1   44.86  ? 83  LEU C CA  1 
ATOM   5220 C  C   . LEU C 1 87  ? -32.296 21.069  23.236  1   50.44  ? 83  LEU C C   1 
ATOM   5221 O  O   . LEU C 1 87  ? -31.616 21.577  22.341  1   47.25  ? 83  LEU C O   1 
ATOM   5222 C  CB  . LEU C 1 87  ? -34.125 19.246  23.402  1   43.49  ? 83  LEU C CB  1 
ATOM   5223 C  CG  . LEU C 1 87  ? -34.655 18.016  22.652  1   42.57  ? 83  LEU C CG  1 
ATOM   5224 C  CD1 . LEU C 1 87  ? -34.831 16.824  23.569  1   49.04  ? 83  LEU C CD1 1 
ATOM   5225 C  CD2 . LEU C 1 87  ? -35.968 18.329  21.983  1   41.85  ? 83  LEU C CD2 1 
ATOM   5226 N  N   . HIS C 1 88  ? -32.76  21.787  24.274  1   54.82  ? 84  HIS C N   1 
ATOM   5227 C  CA  . HIS C 1 88  ? -32.482 23.215  24.408  1   47.82  ? 84  HIS C CA  1 
ATOM   5228 C  C   . HIS C 1 88  ? -32.92  23.755  25.77   1   42.03  ? 84  HIS C C   1 
ATOM   5229 O  O   . HIS C 1 88  ? -32.093 24.28   26.511  1   42.34  ? 84  HIS C O   1 
ATOM   5230 C  CB  . HIS C 1 88  ? -33.114 24.016  23.274  1   50.01  ? 84  HIS C CB  1 
ATOM   5231 C  CG  . HIS C 1 88  ? -32.718 25.438  23.371  1   60.49  ? 84  HIS C CG  1 
ATOM   5232 N  ND1 . HIS C 1 88  ? -33.569 26.429  23.813  1   57.83  ? 84  HIS C ND1 1 
ATOM   5233 C  CD2 . HIS C 1 88  ? -31.543 26.024  23.106  1   65.61  ? 84  HIS C CD2 1 
ATOM   5234 C  CE1 . HIS C 1 88  ? -32.921 27.584  23.8    1   64.83  ? 84  HIS C CE1 1 
ATOM   5235 N  NE2 . HIS C 1 88  ? -31.69  27.362  23.369  1   68.58  ? 84  HIS C NE2 1 
ATOM   5236 N  N   . GLN C 1 89  ? -34.218 23.63   26.092  1   34.87  ? 85  GLN C N   1 
ATOM   5237 C  CA  . GLN C 1 89  ? -34.67  23.811  27.464  1   34.33  ? 85  GLN C CA  1 
ATOM   5238 C  C   . GLN C 1 89  ? -35.987 23.071  27.693  1   30.84  ? 85  GLN C C   1 
ATOM   5239 O  O   . GLN C 1 89  ? -36.538 22.481  26.776  1   30.4   ? 85  GLN C O   1 
ATOM   5240 C  CB  . GLN C 1 89  ? -34.8   25.295  27.801  1   38.03  ? 85  GLN C CB  1 
ATOM   5241 C  CG  . GLN C 1 89  ? -35.709 26.071  26.852  1   37.37  ? 85  GLN C CG  1 
ATOM   5242 C  CD  . GLN C 1 89  ? -35.81  27.533  27.235  1   42.61  ? 85  GLN C CD  1 
ATOM   5243 O  OE1 . GLN C 1 89  ? -35.259 27.963  28.256  1   45.71  ? 85  GLN C OE1 1 
ATOM   5244 N  NE2 . GLN C 1 89  ? -36.538 28.31   26.441  1   41.35  ? 85  GLN C NE2 1 
ATOM   5245 N  N   . ASP C 1 90  ? -36.492 23.119  28.93   1   28.57  ? 86  ASP C N   1 
ATOM   5246 C  CA  . ASP C 1 90  ? -37.787 22.547  29.274  1   28.8   ? 86  ASP C CA  1 
ATOM   5247 C  C   . ASP C 1 90  ? -38.906 23.597  29.16   1   28.5   ? 86  ASP C C   1 
ATOM   5248 O  O   . ASP C 1 90  ? -38.648 24.801  29.147  1   29.3   ? 86  ASP C O   1 
ATOM   5249 C  CB  . ASP C 1 90  ? -37.724 21.916  30.655  1   28.4   ? 86  ASP C CB  1 
ATOM   5250 C  CG  . ASP C 1 90  ? -37.472 22.895  31.789  1   29.74  ? 86  ASP C CG  1 
ATOM   5251 O  OD1 . ASP C 1 90  ? -38.291 23.827  31.967  1   29.33  ? 86  ASP C OD1 1 
ATOM   5252 O  OD2 . ASP C 1 90  ? -36.449 22.721  32.478  1   35.7   ? 86  ASP C OD2 1 
ATOM   5253 N  N   . LEU C 1 91  ? -40.163 23.139  29.153  1   25.21  ? 87  LEU C N   1 
ATOM   5254 C  CA  . LEU C 1 91  ? -41.304 24.006  28.912  1   25.93  ? 87  LEU C CA  1 
ATOM   5255 C  C   . LEU C 1 91  ? -41.451 25.008  30.048  1   27.75  ? 87  LEU C C   1 
ATOM   5256 O  O   . LEU C 1 91  ? -41.91  26.134  29.826  1   31.43  ? 87  LEU C O   1 
ATOM   5257 C  CB  . LEU C 1 91  ? -42.579 23.177  28.762  1   25.97  ? 87  LEU C CB  1 
ATOM   5258 C  CG  . LEU C 1 91  ? -43.818 23.915  28.243  1   24.96  ? 87  LEU C CG  1 
ATOM   5259 C  CD1 . LEU C 1 91  ? -43.616 24.42   26.828  1   25.19  ? 87  LEU C CD1 1 
ATOM   5260 C  CD2 . LEU C 1 91  ? -45.019 22.999  28.268  1   24.85  ? 87  LEU C CD2 1 
ATOM   5261 N  N   . LYS C 1 92  ? -41.094 24.586  31.265  1   26.89  ? 88  LYS C N   1 
ATOM   5262 C  CA  . LYS C 1 92  ? -41.165 25.474  32.419  1   28.12  ? 88  LYS C CA  1 
ATOM   5263 C  C   . LYS C 1 92  ? -40.225 26.662  32.202  1   29.25  ? 88  LYS C C   1 
ATOM   5264 O  O   . LYS C 1 92  ? -40.606 27.799  32.433  1   25.99  ? 88  LYS C O   1 
ATOM   5265 C  CB  . LYS C 1 92  ? -40.919 24.698  33.716  1   27.23  ? 88  LYS C CB  1 
ATOM   5266 C  CG  . LYS C 1 92  ? -40.538 25.497  34.944  1   31.83  ? 88  LYS C CG  1 
ATOM   5267 C  CD  . LYS C 1 92  ? -41.529 26.58   35.347  1   36.19  ? 88  LYS C CD  1 
ATOM   5268 C  CE  . LYS C 1 92  ? -42.945 26.108  35.352  1   39.72  ? 88  LYS C CE  1 
ATOM   5269 N  NZ  . LYS C 1 92  ? -43.777 27.227  35.81   1   47.61  ? 88  LYS C NZ  1 
ATOM   5270 N  N   . LYS C 1 93  ? -38.999 26.399  31.735  1   31.44  ? 89  LYS C N   1 
ATOM   5271 C  CA  . LYS C 1 93  ? -38.048 27.473  31.511  1   32.09  ? 89  LYS C CA  1 
ATOM   5272 C  C   . LYS C 1 93  ? -38.582 28.42   30.44   1   28.02  ? 89  LYS C C   1 
ATOM   5273 O  O   . LYS C 1 93  ? -38.46  29.651  30.573  1   25.3   ? 89  LYS C O   1 
ATOM   5274 C  CB  . LYS C 1 93  ? -36.69  26.924  31.059  1   40.64  ? 89  LYS C CB  1 
ATOM   5275 C  CG  . LYS C 1 93  ? -35.649 26.701  32.153  1   54.38  ? 89  LYS C CG  1 
ATOM   5276 C  CD  . LYS C 1 93  ? -34.224 26.823  31.603  1   68.12  ? 89  LYS C CD  1 
ATOM   5277 C  CE  . LYS C 1 93  ? -33.135 26.646  32.623  1   66.96  ? 89  LYS C CE  1 
ATOM   5278 N  NZ  . LYS C 1 93  ? -33.193 25.264  33.108  1   65.27  ? 89  LYS C NZ  1 
ATOM   5279 N  N   . PHE C 1 94  ? -39.133 27.813  29.376  1   23.44  ? 90  PHE C N   1 
ATOM   5280 C  CA  . PHE C 1 94  ? -39.62  28.546  28.223  1   23.65  ? 90  PHE C CA  1 
ATOM   5281 C  C   . PHE C 1 94  ? -40.775 29.467  28.624  1   26.87  ? 90  PHE C C   1 
ATOM   5282 O  O   . PHE C 1 94  ? -40.755 30.663  28.286  1   27.15  ? 90  PHE C O   1 
ATOM   5283 C  CB  . PHE C 1 94  ? -40.083 27.597  27.124  1   22.14  ? 90  PHE C CB  1 
ATOM   5284 C  CG  . PHE C 1 94  ? -40.639 28.341  25.919  1   22.58  ? 90  PHE C CG  1 
ATOM   5285 C  CD1 . PHE C 1 94  ? -39.868 29.298  25.249  1   21.87  ? 90  PHE C CD1 1 
ATOM   5286 C  CD2 . PHE C 1 94  ? -41.944 28.11   25.488  1   21.47  ? 90  PHE C CD2 1 
ATOM   5287 C  CE1 . PHE C 1 94  ? -40.378 29.966  24.15   1   20.51  ? 90  PHE C CE1 1 
ATOM   5288 C  CE2 . PHE C 1 94  ? -42.453 28.773  24.384  1   20.46  ? 90  PHE C CE2 1 
ATOM   5289 C  CZ  . PHE C 1 94  ? -41.664 29.69   23.716  1   21.4   ? 90  PHE C CZ  1 
ATOM   5290 N  N   . MET C 1 95  ? -41.768 28.884  29.33   1   26.46  ? 91  MET C N   1 
ATOM   5291 C  CA  . MET C 1 95  ? -42.926 29.596  29.851  1   25.76  ? 91  MET C CA  1 
ATOM   5292 C  C   . MET C 1 95  ? -42.48  30.794  30.683  1   25.21  ? 91  MET C C   1 
ATOM   5293 O  O   . MET C 1 95  ? -42.893 31.929  30.422  1   26.18  ? 91  MET C O   1 
ATOM   5294 C  CB  . MET C 1 95  ? -43.84  28.672  30.657  1   26.97  ? 91  MET C CB  1 
ATOM   5295 C  CG  . MET C 1 95  ? -44.831 27.918  29.801  1   31.77  ? 91  MET C CG  1 
ATOM   5296 S  SD  . MET C 1 95  ? -45.984 26.855  30.699  1   42.61  ? 91  MET C SD  1 
ATOM   5297 C  CE  . MET C 1 95  ? -44.889 26.028  31.856  1   36.06  ? 91  MET C CE  1 
ATOM   5298 N  N   . ASP C 1 96  ? -41.613 30.527  31.665  1   25.32  ? 92  ASP C N   1 
ATOM   5299 C  CA  . ASP C 1 96  ? -41.049 31.555  32.53   1   25.99  ? 92  ASP C CA  1 
ATOM   5300 C  C   . ASP C 1 96  ? -40.41  32.672  31.713  1   24.75  ? 92  ASP C C   1 
ATOM   5301 O  O   . ASP C 1 96  ? -40.61  33.844  32.011  1   22.35  ? 92  ASP C O   1 
ATOM   5302 C  CB  . ASP C 1 96  ? -40.032 30.985  33.502  1   26.68  ? 92  ASP C CB  1 
ATOM   5303 C  CG  . ASP C 1 96  ? -40.641 30.124  34.591  1   30     ? 92  ASP C CG  1 
ATOM   5304 O  OD1 . ASP C 1 96  ? -41.877 30.235  34.786  1   31.13  ? 92  ASP C OD1 1 
ATOM   5305 O  OD2 . ASP C 1 96  ? -39.884 29.332  35.19   1   34.01  ? 92  ASP C OD2 1 
ATOM   5306 N  N   . ALA C 1 97  ? -39.61  32.293  30.709  1   24.01  ? 93  ALA C N   1 
ATOM   5307 C  CA  . ALA C 1 97  ? -38.893 33.262  29.899  1   22.47  ? 93  ALA C CA  1 
ATOM   5308 C  C   . ALA C 1 97  ? -39.894 34.107  29.13   1   22.03  ? 93  ALA C C   1 
ATOM   5309 O  O   . ALA C 1 97  ? -39.61  35.256  28.821  1   20.47  ? 93  ALA C O   1 
ATOM   5310 C  CB  . ALA C 1 97  ? -37.954 32.546  28.952  1   21.71  ? 93  ALA C CB  1 
ATOM   5311 N  N   . SER C 1 98  ? -41.047 33.499  28.83   1   26.35  ? 94  SER C N   1 
ATOM   5312 C  CA  . SER C 1 98  ? -42.11  34.082  28.027  1   31.1   ? 94  SER C CA  1 
ATOM   5313 C  C   . SER C 1 98  ? -43.203 34.696  28.904  1   36.67  ? 94  SER C C   1 
ATOM   5314 O  O   . SER C 1 98  ? -44.318 34.897  28.436  1   35.5   ? 94  SER C O   1 
ATOM   5315 C  CB  . SER C 1 98  ? -42.71  33.028  27.125  1   27.77  ? 94  SER C CB  1 
ATOM   5316 O  OG  . SER C 1 98  ? -41.763 32.536  26.194  1   28.78  ? 94  SER C OG  1 
ATOM   5317 N  N   . ALA C 1 99  ? -42.892 34.98   30.176  1   46.61  ? 95  ALA C N   1 
ATOM   5318 C  CA  . ALA C 1 99  ? -43.9   35.36   31.157  1   50.58  ? 95  ALA C CA  1 
ATOM   5319 C  C   . ALA C 1 99  ? -44.381 36.796  30.937  1   50.48  ? 95  ALA C C   1 
ATOM   5320 O  O   . ALA C 1 99  ? -45.501 37.123  31.317  1   49.4   ? 95  ALA C O   1 
ATOM   5321 C  CB  . ALA C 1 99  ? -43.39  35.153  32.561  1   54.07  ? 95  ALA C CB  1 
ATOM   5322 N  N   . LEU C 1 100 ? -43.567 37.63   30.282  1   45.21  ? 96  LEU C N   1 
ATOM   5323 C  CA  . LEU C 1 100 ? -44.007 38.977  29.965  1   47.41  ? 96  LEU C CA  1 
ATOM   5324 C  C   . LEU C 1 100 ? -44.546 39.062  28.535  1   54.39  ? 96  LEU C C   1 
ATOM   5325 O  O   . LEU C 1 100 ? -45.523 39.772  28.288  1   64.19  ? 96  LEU C O   1 
ATOM   5326 C  CB  . LEU C 1 100 ? -42.885 39.991  30.187  1   46.45  ? 96  LEU C CB  1 
ATOM   5327 C  CG  . LEU C 1 100 ? -42.213 39.976  31.563  1   45.48  ? 96  LEU C CG  1 
ATOM   5328 C  CD1 . LEU C 1 100 ? -41.363 41.217  31.743  1   43.61  ? 96  LEU C CD1 1 
ATOM   5329 C  CD2 . LEU C 1 100 ? -43.175 39.799  32.728  1   47.08  ? 96  LEU C CD2 1 
ATOM   5330 N  N   . THR C 1 101 ? -43.864 38.381  27.596  1   49.5   ? 97  THR C N   1 
ATOM   5331 C  CA  . THR C 1 101 ? -44.115 38.486  26.16   1   40.28  ? 97  THR C CA  1 
ATOM   5332 C  C   . THR C 1 101 ? -45.281 37.588  25.746  1   38.37  ? 97  THR C C   1 
ATOM   5333 O  O   . THR C 1 101 ? -45.931 37.837  24.742  1   41.98  ? 97  THR C O   1 
ATOM   5334 C  CB  . THR C 1 101 ? -42.862 38.187  25.328  1   37.47  ? 97  THR C CB  1 
ATOM   5335 O  OG1 . THR C 1 101 ? -42.469 36.821  25.477  1   33.98  ? 97  THR C OG1 1 
ATOM   5336 C  CG2 . THR C 1 101 ? -41.715 39.126  25.661  1   37.05  ? 97  THR C CG2 1 
ATOM   5337 N  N   . GLY C 1 102 ? -45.532 36.519  26.496  1   38.53  ? 98  GLY C N   1 
ATOM   5338 C  CA  . GLY C 1 102 ? -46.562 35.561  26.124  1   36.28  ? 98  GLY C CA  1 
ATOM   5339 C  C   . GLY C 1 102 ? -46.075 34.595  25.044  1   32.47  ? 98  GLY C C   1 
ATOM   5340 O  O   . GLY C 1 102 ? -45.097 34.863  24.344  1   28.79  ? 98  GLY C O   1 
ATOM   5341 N  N   . ILE C 1 103 ? -46.77  33.457  24.949  1   30.58  ? 99  ILE C N   1 
ATOM   5342 C  CA  . ILE C 1 103 ? -46.514 32.449  23.937  1   30.24  ? 99  ILE C CA  1 
ATOM   5343 C  C   . ILE C 1 103 ? -47.558 32.576  22.82   1   31.28  ? 99  ILE C C   1 
ATOM   5344 O  O   . ILE C 1 103 ? -48.767 32.578  23.079  1   32.33  ? 99  ILE C O   1 
ATOM   5345 C  CB  . ILE C 1 103 ? -46.566 31.063  24.596  1   30.11  ? 99  ILE C CB  1 
ATOM   5346 C  CG1 . ILE C 1 103 ? -45.714 31.008  25.866  1   29.45  ? 99  ILE C CG1 1 
ATOM   5347 C  CG2 . ILE C 1 103 ? -46.195 29.976  23.591  1   28.22  ? 99  ILE C CG2 1 
ATOM   5348 C  CD1 . ILE C 1 103 ? -45.838 29.695  26.616  1   26.43  ? 99  ILE C CD1 1 
ATOM   5349 N  N   . PRO C 1 104 ? -47.137 32.71   21.54   1   29.24  ? 100 PRO C N   1 
ATOM   5350 C  CA  . PRO C 1 104 ? -48.081 32.698  20.423  1   29.03  ? 100 PRO C CA  1 
ATOM   5351 C  C   . PRO C 1 104 ? -48.994 31.474  20.416  1   29.84  ? 100 PRO C C   1 
ATOM   5352 O  O   . PRO C 1 104 ? -48.565 30.366  20.706  1   28.39  ? 100 PRO C O   1 
ATOM   5353 C  CB  . PRO C 1 104 ? -47.17  32.784  19.182  1   27.15  ? 100 PRO C CB  1 
ATOM   5354 C  CG  . PRO C 1 104 ? -45.943 33.506  19.689  1   26.8   ? 100 PRO C CG  1 
ATOM   5355 C  CD  . PRO C 1 104 ? -45.754 32.974  21.103  1   28.33  ? 100 PRO C CD  1 
ATOM   5356 N  N   . LEU C 1 105 ? -50.255 31.699  20.042  1   33.02  ? 101 LEU C N   1 
ATOM   5357 C  CA  . LEU C 1 105 ? -51.292 30.681  20.073  1   36.67  ? 101 LEU C CA  1 
ATOM   5358 C  C   . LEU C 1 105 ? -50.961 29.522  19.128  1   32.86  ? 101 LEU C C   1 
ATOM   5359 O  O   . LEU C 1 105 ? -51.222 28.376  19.475  1   32.26  ? 101 LEU C O   1 
ATOM   5360 C  CB  . LEU C 1 105 ? -52.652 31.334  19.794  1   42.84  ? 101 LEU C CB  1 
ATOM   5361 C  CG  . LEU C 1 105 ? -53.913 30.476  19.975  1   47.62  ? 101 LEU C CG  1 
ATOM   5362 C  CD1 . LEU C 1 105 ? -54.244 29.643  18.722  1   46.72  ? 101 LEU C CD1 1 
ATOM   5363 C  CD2 . LEU C 1 105 ? -53.824 29.593  21.224  1   43.99  ? 101 LEU C CD2 1 
ATOM   5364 N  N   . PRO C 1 106 ? -50.418 29.748  17.905  1   32.12  ? 102 PRO C N   1 
ATOM   5365 C  CA  . PRO C 1 106 ? -50.057 28.639  17.018  1   29.53  ? 102 PRO C CA  1 
ATOM   5366 C  C   . PRO C 1 106 ? -48.976 27.736  17.595  1   28.5   ? 102 PRO C C   1 
ATOM   5367 O  O   . PRO C 1 106 ? -48.97  26.54   17.295  1   30.96  ? 102 PRO C O   1 
ATOM   5368 C  CB  . PRO C 1 106 ? -49.613 29.313  15.697  1   28.45  ? 102 PRO C CB  1 
ATOM   5369 C  CG  . PRO C 1 106 ? -50.182 30.714  15.785  1   26.25  ? 102 PRO C CG  1 
ATOM   5370 C  CD  . PRO C 1 106 ? -50.201 31.058  17.262  1   28.39  ? 102 PRO C CD  1 
ATOM   5371 N  N   . LEU C 1 107 ? -48.076 28.314  18.409  1   27.38  ? 103 LEU C N   1 
ATOM   5372 C  CA  . LEU C 1 107 ? -47.02  27.556  19.077  1   26.68  ? 103 LEU C CA  1 
ATOM   5373 C  C   . LEU C 1 107 ? -47.597 26.707  20.218  1   25.89  ? 103 LEU C C   1 
ATOM   5374 O  O   . LEU C 1 107 ? -47.209 25.544  20.389  1   26.66  ? 103 LEU C O   1 
ATOM   5375 C  CB  . LEU C 1 107 ? -45.85  28.428  19.55   1   25.95  ? 103 LEU C CB  1 
ATOM   5376 C  CG  . LEU C 1 107 ? -44.592 27.681  20.032  1   26.07  ? 103 LEU C CG  1 
ATOM   5377 C  CD1 . LEU C 1 107 ? -43.835 26.915  18.938  1   24.58  ? 103 LEU C CD1 1 
ATOM   5378 C  CD2 . LEU C 1 107 ? -43.646 28.634  20.742  1   24.86  ? 103 LEU C CD2 1 
ATOM   5379 N  N   . ILE C 1 108 ? -48.52  27.302  20.991  1   25.04  ? 104 ILE C N   1 
ATOM   5380 C  CA  . ILE C 1 108 ? -49.257 26.594  22.031  1   26.06  ? 104 ILE C CA  1 
ATOM   5381 C  C   . ILE C 1 108 ? -49.933 25.361  21.428  1   28.04  ? 104 ILE C C   1 
ATOM   5382 O  O   . ILE C 1 108 ? -49.856 24.255  21.987  1   29.46  ? 104 ILE C O   1 
ATOM   5383 C  CB  . ILE C 1 108 ? -50.267 27.512  22.753  1   22.8   ? 104 ILE C CB  1 
ATOM   5384 C  CG1 . ILE C 1 108 ? -49.563 28.675  23.458  1   22.05  ? 104 ILE C CG1 1 
ATOM   5385 C  CG2 . ILE C 1 108 ? -51.144 26.708  23.717  1   20.02  ? 104 ILE C CG2 1 
ATOM   5386 C  CD1 . ILE C 1 108 ? -50.482 29.595  24.241  1   21.7   ? 104 ILE C CD1 1 
ATOM   5387 N  N   . LYS C 1 109 ? -50.603 25.582  20.293  1   26.19  ? 105 LYS C N   1 
ATOM   5388 C  CA  . LYS C 1 109 ? -51.387 24.545  19.642  1   27.36  ? 105 LYS C CA  1 
ATOM   5389 C  C   . LYS C 1 109 ? -50.476 23.476  19.049  1   27.49  ? 105 LYS C C   1 
ATOM   5390 O  O   . LYS C 1 109 ? -50.806 22.293  19.113  1   27.78  ? 105 LYS C O   1 
ATOM   5391 C  CB  . LYS C 1 109 ? -52.244 25.164  18.538  1   27.38  ? 105 LYS C CB  1 
ATOM   5392 C  CG  . LYS C 1 109 ? -53.143 24.202  17.784  1   26.16  ? 105 LYS C CG  1 
ATOM   5393 C  CD  . LYS C 1 109 ? -53.907 24.951  16.7    1   24.18  ? 105 LYS C CD  1 
ATOM   5394 C  CE  . LYS C 1 109 ? -54.74  26.083  17.224  1   22.57  ? 105 LYS C CE  1 
ATOM   5395 N  NZ  . LYS C 1 109 ? -55.501 26.753  16.169  1   21.81  ? 105 LYS C NZ  1 
ATOM   5396 N  N   . SER C 1 110 ? -49.352 23.905  18.453  1   27.42  ? 106 SER C N   1 
ATOM   5397 C  CA  . SER C 1 110 ? -48.369 22.962  17.942  1   26.95  ? 106 SER C CA  1 
ATOM   5398 C  C   . SER C 1 110 ? -47.829 22.089  19.08   1   27.46  ? 106 SER C C   1 
ATOM   5399 O  O   . SER C 1 110 ? -47.785 20.859  18.964  1   25.81  ? 106 SER C O   1 
ATOM   5400 C  CB  . SER C 1 110 ? -47.248 23.662  17.238  1   24.68  ? 106 SER C CB  1 
ATOM   5401 O  OG  . SER C 1 110 ? -46.386 22.719  16.604  1   24.73  ? 106 SER C OG  1 
ATOM   5402 N  N   . TYR C 1 111 ? -47.424 22.751  20.173  1   25.63  ? 107 TYR C N   1 
ATOM   5403 C  CA  . TYR C 1 111 ? -46.864 22.078  21.33   1   26.07  ? 107 TYR C CA  1 
ATOM   5404 C  C   . TYR C 1 111 ? -47.848 21.027  21.843  1   27.28  ? 107 TYR C C   1 
ATOM   5405 O  O   . TYR C 1 111 ? -47.465 19.88   22.057  1   33.85  ? 107 TYR C O   1 
ATOM   5406 C  CB  . TYR C 1 111 ? -46.423 23.095  22.39   1   25.81  ? 107 TYR C CB  1 
ATOM   5407 C  CG  . TYR C 1 111 ? -45.055 23.73   22.168  1   25.61  ? 107 TYR C CG  1 
ATOM   5408 C  CD1 . TYR C 1 111 ? -44.212 23.322  21.126  1   24.57  ? 107 TYR C CD1 1 
ATOM   5409 C  CD2 . TYR C 1 111 ? -44.578 24.694  23.054  1   23.72  ? 107 TYR C CD2 1 
ATOM   5410 C  CE1 . TYR C 1 111 ? -42.94  23.854  20.972  1   24.14  ? 107 TYR C CE1 1 
ATOM   5411 C  CE2 . TYR C 1 111 ? -43.317 25.246  22.893  1   23.94  ? 107 TYR C CE2 1 
ATOM   5412 C  CZ  . TYR C 1 111 ? -42.498 24.829  21.854  1   24.31  ? 107 TYR C CZ  1 
ATOM   5413 O  OH  . TYR C 1 111 ? -41.256 25.375  21.707  1   24.66  ? 107 TYR C OH  1 
ATOM   5414 N  N   . LEU C 1 112 ? -49.119 21.41   21.999  1   26.58  ? 108 LEU C N   1 
ATOM   5415 C  CA  . LEU C 1 112 ? -50.124 20.503  22.524  1   27.11  ? 108 LEU C CA  1 
ATOM   5416 C  C   . LEU C 1 112 ? -50.36  19.358  21.547  1   26.3   ? 108 LEU C C   1 
ATOM   5417 O  O   . LEU C 1 112 ? -50.527 18.221  21.97   1   27.17  ? 108 LEU C O   1 
ATOM   5418 C  CB  . LEU C 1 112 ? -51.421 21.25   22.82   1   29.29  ? 108 LEU C CB  1 
ATOM   5419 C  CG  . LEU C 1 112 ? -52.505 20.431  23.537  1   30.9   ? 108 LEU C CG  1 
ATOM   5420 C  CD1 . LEU C 1 112 ? -52.1   20.025  24.944  1   28.58  ? 108 LEU C CD1 1 
ATOM   5421 C  CD2 . LEU C 1 112 ? -53.81  21.206  23.579  1   31.24  ? 108 LEU C CD2 1 
ATOM   5422 N  N   . PHE C 1 113 ? -50.379 19.659  20.244  1   28.28  ? 109 PHE C N   1 
ATOM   5423 C  CA  . PHE C 1 113 ? -50.588 18.633  19.229  1   28.68  ? 109 PHE C CA  1 
ATOM   5424 C  C   . PHE C 1 113 ? -49.532 17.527  19.376  1   29.17  ? 109 PHE C C   1 
ATOM   5425 O  O   . PHE C 1 113 ? -49.828 16.326  19.341  1   26.5   ? 109 PHE C O   1 
ATOM   5426 C  CB  . PHE C 1 113 ? -50.592 19.326  17.862  1   29.37  ? 109 PHE C CB  1 
ATOM   5427 C  CG  . PHE C 1 113 ? -51.025 18.431  16.713  1   30.76  ? 109 PHE C CG  1 
ATOM   5428 C  CD1 . PHE C 1 113 ? -52.239 17.749  16.769  1   32.68  ? 109 PHE C CD1 1 
ATOM   5429 C  CD2 . PHE C 1 113 ? -50.201 18.245  15.605  1   30.83  ? 109 PHE C CD2 1 
ATOM   5430 C  CE1 . PHE C 1 113 ? -52.624 16.909  15.737  1   33.81  ? 109 PHE C CE1 1 
ATOM   5431 C  CE2 . PHE C 1 113 ? -50.586 17.398  14.576  1   31.81  ? 109 PHE C CE2 1 
ATOM   5432 C  CZ  . PHE C 1 113 ? -51.793 16.732  14.641  1   33.62  ? 109 PHE C CZ  1 
ATOM   5433 N  N   . GLN C 1 114 ? -48.284 17.95   19.596  1   29.3   ? 110 GLN C N   1 
ATOM   5434 C  CA  . GLN C 1 114 ? -47.15  17.042  19.641  1   29.68  ? 110 GLN C CA  1 
ATOM   5435 C  C   . GLN C 1 114 ? -47.099 16.293  20.977  1   30.57  ? 110 GLN C C   1 
ATOM   5436 O  O   . GLN C 1 114 ? -46.681 15.13   21.033  1   29.37  ? 110 GLN C O   1 
ATOM   5437 C  CB  . GLN C 1 114 ? -45.873 17.856  19.435  1   30.69  ? 110 GLN C CB  1 
ATOM   5438 C  CG  . GLN C 1 114 ? -45.739 18.581  18.101  1   26.44  ? 110 GLN C CG  1 
ATOM   5439 C  CD  . GLN C 1 114 ? -44.403 19.282  18.029  1   29.62  ? 110 GLN C CD  1 
ATOM   5440 O  OE1 . GLN C 1 114 ? -43.348 18.633  18.01   1   31.49  ? 110 GLN C OE1 1 
ATOM   5441 N  NE2 . GLN C 1 114 ? -44.434 20.61   18.062  1   27.21  ? 110 GLN C NE2 1 
ATOM   5442 N  N   . LEU C 1 115 ? -47.49  16.984  22.061  1   29.1   ? 111 LEU C N   1 
ATOM   5443 C  CA  . LEU C 1 115 ? -47.573 16.397  23.391  1   28.57  ? 111 LEU C CA  1 
ATOM   5444 C  C   . LEU C 1 115 ? -48.611 15.277  23.407  1   29.82  ? 111 LEU C C   1 
ATOM   5445 O  O   . LEU C 1 115 ? -48.483 14.31   24.168  1   31.64  ? 111 LEU C O   1 
ATOM   5446 C  CB  . LEU C 1 115 ? -47.927 17.474  24.414  1   26.78  ? 111 LEU C CB  1 
ATOM   5447 C  CG  . LEU C 1 115 ? -46.795 18.417  24.819  1   26.86  ? 111 LEU C CG  1 
ATOM   5448 C  CD1 . LEU C 1 115 ? -47.311 19.494  25.744  1   24.26  ? 111 LEU C CD1 1 
ATOM   5449 C  CD2 . LEU C 1 115 ? -45.685 17.629  25.494  1   26.73  ? 111 LEU C CD2 1 
ATOM   5450 N  N   . LEU C 1 116 ? -49.669 15.452  22.604  1   27.98  ? 112 LEU C N   1 
ATOM   5451 C  CA  . LEU C 1 116 ? -50.71  14.442  22.5    1   28.78  ? 112 LEU C CA  1 
ATOM   5452 C  C   . LEU C 1 116 ? -50.259 13.289  21.594  1   30.31  ? 112 LEU C C   1 
ATOM   5453 O  O   . LEU C 1 116 ? -50.638 12.133  21.805  1   29.69  ? 112 LEU C O   1 
ATOM   5454 C  CB  . LEU C 1 116 ? -51.991 15.106  22.01   1   25.62  ? 112 LEU C CB  1 
ATOM   5455 C  CG  . LEU C 1 116 ? -52.727 15.935  23.059  1   23.66  ? 112 LEU C CG  1 
ATOM   5456 C  CD1 . LEU C 1 116 ? -53.802 16.768  22.36   1   23.06  ? 112 LEU C CD1 1 
ATOM   5457 C  CD2 . LEU C 1 116 ? -53.336 15.053  24.129  1   22.62  ? 112 LEU C CD2 1 
ATOM   5458 N  N   . GLN C 1 117 ? -49.439 13.61   20.586  1   29.02  ? 113 GLN C N   1 
ATOM   5459 C  CA  . GLN C 1 117 ? -48.88  12.572  19.742  1   29.82  ? 113 GLN C CA  1 
ATOM   5460 C  C   . GLN C 1 117 ? -47.922 11.686  20.536  1   32.05  ? 113 GLN C C   1 
ATOM   5461 O  O   . GLN C 1 117 ? -47.972 10.461  20.426  1   33.77  ? 113 GLN C O   1 
ATOM   5462 C  CB  . GLN C 1 117 ? -48.226 13.199  18.524  1   28.86  ? 113 GLN C CB  1 
ATOM   5463 C  CG  . GLN C 1 117 ? -49.232 13.651  17.488  1   30.35  ? 113 GLN C CG  1 
ATOM   5464 C  CD  . GLN C 1 117 ? -48.517 14.004  16.217  1   35.82  ? 113 GLN C CD  1 
ATOM   5465 O  OE1 . GLN C 1 117 ? -48.587 13.271  15.233  1   44.34  ? 113 GLN C OE1 1 
ATOM   5466 N  NE2 . GLN C 1 117 ? -47.763 15.09   16.241  1   39.79  ? 113 GLN C NE2 1 
ATOM   5467 N  N   . GLY C 1 118 ? -47.049 12.312  21.334  1   30.93  ? 114 GLY C N   1 
ATOM   5468 C  CA  . GLY C 1 118 ? -46.136 11.579  22.188  1   26.55  ? 114 GLY C CA  1 
ATOM   5469 C  C   . GLY C 1 118 ? -46.891 10.649  23.127  1   28.01  ? 114 GLY C C   1 
ATOM   5470 O  O   . GLY C 1 118 ? -46.509 9.49    23.287  1   28.53  ? 114 GLY C O   1 
ATOM   5471 N  N   . LEU C 1 119 ? -47.951 11.179  23.752  1   27.71  ? 115 LEU C N   1 
ATOM   5472 C  CA  . LEU C 1 119 ? -48.665 10.469  24.8    1   26.42  ? 115 LEU C CA  1 
ATOM   5473 C  C   . LEU C 1 119 ? -49.574 9.388   24.2    1   27.68  ? 115 LEU C C   1 
ATOM   5474 O  O   . LEU C 1 119 ? -49.673 8.295   24.763  1   27.55  ? 115 LEU C O   1 
ATOM   5475 C  CB  . LEU C 1 119 ? -49.428 11.476  25.663  1   24.24  ? 115 LEU C CB  1 
ATOM   5476 C  CG  . LEU C 1 119 ? -50.208 10.881  26.837  1   22.19  ? 115 LEU C CG  1 
ATOM   5477 C  CD1 . LEU C 1 119 ? -49.262 10.385  27.906  1   22.15  ? 115 LEU C CD1 1 
ATOM   5478 C  CD2 . LEU C 1 119 ? -51.217 11.853  27.413  1   20.86  ? 115 LEU C CD2 1 
ATOM   5479 N  N   . ALA C 1 120 ? -50.257 9.686   23.078  1   24.89  ? 116 ALA C N   1 
ATOM   5480 C  CA  . ALA C 1 120 ? -50.984 8.662   22.337  1   26.1   ? 116 ALA C CA  1 
ATOM   5481 C  C   . ALA C 1 120 ? -50.101 7.419   22.107  1   28.12  ? 116 ALA C C   1 
ATOM   5482 O  O   . ALA C 1 120 ? -50.535 6.27    22.29   1   25.63  ? 116 ALA C O   1 
ATOM   5483 C  CB  . ALA C 1 120 ? -51.491 9.24    21.03   1   25.42  ? 116 ALA C CB  1 
ATOM   5484 N  N   . PHE C 1 121 ? -48.833 7.668   21.738  1   27.9   ? 117 PHE C N   1 
ATOM   5485 C  CA  . PHE C 1 121 ? -47.825 6.642   21.523  1   27.19  ? 117 PHE C CA  1 
ATOM   5486 C  C   . PHE C 1 121 ? -47.521 5.867   22.806  1   28.32  ? 117 PHE C C   1 
ATOM   5487 O  O   . PHE C 1 121 ? -47.416 4.643   22.762  1   31.93  ? 117 PHE C O   1 
ATOM   5488 C  CB  . PHE C 1 121 ? -46.553 7.28    20.959  1   27.96  ? 117 PHE C CB  1 
ATOM   5489 C  CG  . PHE C 1 121 ? -45.626 6.262   20.317  1   29.24  ? 117 PHE C CG  1 
ATOM   5490 C  CD1 . PHE C 1 121 ? -44.728 5.53    21.107  1   26.87  ? 117 PHE C CD1 1 
ATOM   5491 C  CD2 . PHE C 1 121 ? -45.713 5.997   18.944  1   25.11  ? 117 PHE C CD2 1 
ATOM   5492 C  CE1 . PHE C 1 121 ? -43.899 4.588   20.517  1   27.66  ? 117 PHE C CE1 1 
ATOM   5493 C  CE2 . PHE C 1 121 ? -44.903 5.036   18.363  1   24.7   ? 117 PHE C CE2 1 
ATOM   5494 C  CZ  . PHE C 1 121 ? -43.994 4.338   19.144  1   28.42  ? 117 PHE C CZ  1 
ATOM   5495 N  N   . CYS C 1 122 ? -47.355 6.566   23.941  1   25.19  ? 118 CYS C N   1 
ATOM   5496 C  CA  . CYS C 1 122 ? -47.165 5.869   25.202  1   24.66  ? 118 CYS C CA  1 
ATOM   5497 C  C   . CYS C 1 122 ? -48.341 4.943   25.484  1   25.41  ? 118 CYS C C   1 
ATOM   5498 O  O   . CYS C 1 122 ? -48.141 3.772   25.771  1   26.87  ? 118 CYS C O   1 
ATOM   5499 C  CB  . CYS C 1 122 ? -47.029 6.839   26.358  1   24.92  ? 118 CYS C CB  1 
ATOM   5500 S  SG  . CYS C 1 122 ? -45.491 7.765   26.222  1   30.89  ? 118 CYS C SG  1 
ATOM   5501 N  N   . HIS C 1 123 ? -49.565 5.474   25.382  1   26.7   ? 119 HIS C N   1 
ATOM   5502 C  CA  . HIS C 1 123 ? -50.76  4.737   25.761  1   27.15  ? 119 HIS C CA  1 
ATOM   5503 C  C   . HIS C 1 123 ? -50.969 3.554   24.824  1   26.22  ? 119 HIS C C   1 
ATOM   5504 O  O   . HIS C 1 123 ? -51.372 2.496   25.285  1   27.3   ? 119 HIS C O   1 
ATOM   5505 C  CB  . HIS C 1 123 ? -51.975 5.66    25.895  1   27.33  ? 119 HIS C CB  1 
ATOM   5506 C  CG  . HIS C 1 123 ? -51.816 6.674   26.974  1   29.32  ? 119 HIS C CG  1 
ATOM   5507 N  ND1 . HIS C 1 123 ? -52.684 7.731   27.126  1   29.48  ? 119 HIS C ND1 1 
ATOM   5508 C  CD2 . HIS C 1 123 ? -50.911 6.783   27.974  1   29.92  ? 119 HIS C CD2 1 
ATOM   5509 C  CE1 . HIS C 1 123 ? -52.289 8.461   28.165  1   31.02  ? 119 HIS C CE1 1 
ATOM   5510 N  NE2 . HIS C 1 123 ? -51.222 7.907   28.699  1   30.4   ? 119 HIS C NE2 1 
ATOM   5511 N  N   . SER C 1 124 ? -50.702 3.762   23.526  1   24.73  ? 120 SER C N   1 
ATOM   5512 C  CA  . SER C 1 124 ? -50.743 2.719   22.516  1   25.53  ? 120 SER C CA  1 
ATOM   5513 C  C   . SER C 1 124 ? -49.733 1.621   22.81   1   27.73  ? 120 SER C C   1 
ATOM   5514 O  O   . SER C 1 124 ? -49.821 0.557   22.201  1   28.25  ? 120 SER C O   1 
ATOM   5515 C  CB  . SER C 1 124 ? -50.46  3.268   21.169  1   27.28  ? 120 SER C CB  1 
ATOM   5516 O  OG  . SER C 1 124 ? -51.449 4.227   20.836  1   38.23  ? 120 SER C OG  1 
ATOM   5517 N  N   . HIS C 1 125 ? -48.743 1.913   23.67   1   28.62  ? 121 HIS C N   1 
ATOM   5518 C  CA  . HIS C 1 125 ? -47.65  0.994   23.959  1   28.05  ? 121 HIS C CA  1 
ATOM   5519 C  C   . HIS C 1 125 ? -47.663 0.618   25.436  1   26.25  ? 121 HIS C C   1 
ATOM   5520 O  O   . HIS C 1 125 ? -46.626 0.288   25.986  1   25.91  ? 121 HIS C O   1 
ATOM   5521 C  CB  . HIS C 1 125 ? -46.322 1.603   23.509  1   29.62  ? 121 HIS C CB  1 
ATOM   5522 C  CG  . HIS C 1 125 ? -46.209 1.726   22.027  1   36.66  ? 121 HIS C CG  1 
ATOM   5523 N  ND1 . HIS C 1 125 ? -46.848 2.711   21.301  1   41.84  ? 121 HIS C ND1 1 
ATOM   5524 C  CD2 . HIS C 1 125 ? -45.55  0.973   21.122  1   36.13  ? 121 HIS C CD2 1 
ATOM   5525 C  CE1 . HIS C 1 125 ? -46.562 2.565   20.01   1   37.28  ? 121 HIS C CE1 1 
ATOM   5526 N  NE2 . HIS C 1 125 ? -45.771 1.519   19.883  1   35.54  ? 121 HIS C NE2 1 
ATOM   5527 N  N   . ARG C 1 126 ? -48.845 0.732   26.06   1   26.17  ? 122 ARG C N   1 
ATOM   5528 C  CA  . ARG C 1 126 ? -49.135 0.317   27.427  1   25.19  ? 122 ARG C CA  1 
ATOM   5529 C  C   . ARG C 1 126 ? -48.154 0.928   28.436  1   26.17  ? 122 ARG C C   1 
ATOM   5530 O  O   . ARG C 1 126 ? -47.827 0.296   29.428  1   28.6   ? 122 ARG C O   1 
ATOM   5531 C  CB  . ARG C 1 126 ? -49.232 -1.209  27.49   1   22.68  ? 122 ARG C CB  1 
ATOM   5532 C  CG  . ARG C 1 126 ? -47.976 -1.96   27.056  1   24.03  ? 122 ARG C CG  1 
ATOM   5533 C  CD  . ARG C 1 126 ? -47.072 -2.553  28.158  1   25.74  ? 122 ARG C CD  1 
ATOM   5534 N  NE  . ARG C 1 126 ? -45.954 -3.394  27.697  1   27.57  ? 122 ARG C NE  1 
ATOM   5535 C  CZ  . ARG C 1 126 ? -44.858 -2.977  26.996  1   26.66  ? 122 ARG C CZ  1 
ATOM   5536 N  NH1 . ARG C 1 126 ? -44.679 -1.706  26.654  1   22.23  ? 122 ARG C NH1 1 
ATOM   5537 N  NH2 . ARG C 1 126 ? -43.931 -3.864  26.654  1   28.71  ? 122 ARG C NH2 1 
ATOM   5538 N  N   . VAL C 1 127 ? -47.734 2.182   28.231  1   26.18  ? 123 VAL C N   1 
ATOM   5539 C  CA  . VAL C 1 127 ? -46.936 2.906   29.219  1   26     ? 123 VAL C CA  1 
ATOM   5540 C  C   . VAL C 1 127 ? -47.712 4.128   29.705  1   26.21  ? 123 VAL C C   1 
ATOM   5541 O  O   . VAL C 1 127 ? -48.19  4.929   28.893  1   27.9   ? 123 VAL C O   1 
ATOM   5542 C  CB  . VAL C 1 127 ? -45.567 3.341   28.657  1   24.64  ? 123 VAL C CB  1 
ATOM   5543 C  CG1 . VAL C 1 127 ? -44.847 4.309   29.601  1   21.08  ? 123 VAL C CG1 1 
ATOM   5544 C  CG2 . VAL C 1 127 ? -44.706 2.144   28.25   1   21.81  ? 123 VAL C CG2 1 
ATOM   5545 N  N   . LEU C 1 128 ? -47.84  4.242   31.031  1   25.03  ? 124 LEU C N   1 
ATOM   5546 C  CA  . LEU C 1 128 ? -48.324 5.462   31.669  1   26.22  ? 124 LEU C CA  1 
ATOM   5547 C  C   . LEU C 1 128 ? -47.116 6.322   32.02   1   25.52  ? 124 LEU C C   1 
ATOM   5548 O  O   . LEU C 1 128 ? -46.133 5.785   32.535  1   24.32  ? 124 LEU C O   1 
ATOM   5549 C  CB  . LEU C 1 128 ? -49.1   5.162   32.954  1   27.2   ? 124 LEU C CB  1 
ATOM   5550 C  CG  . LEU C 1 128 ? -50.391 4.345   32.849  1   25.52  ? 124 LEU C CG  1 
ATOM   5551 C  CD1 . LEU C 1 128 ? -50.978 4.174   34.246  1   22.34  ? 124 LEU C CD1 1 
ATOM   5552 C  CD2 . LEU C 1 128 ? -51.339 5.053   31.916  1   24.57  ? 124 LEU C CD2 1 
ATOM   5553 N  N   . HIS C 1 129 ? -47.221 7.642   31.804  1   24.24  ? 125 HIS C N   1 
ATOM   5554 C  CA  . HIS C 1 129 ? -46.12  8.531   32.123  1   25.15  ? 125 HIS C CA  1 
ATOM   5555 C  C   . HIS C 1 129 ? -46.118 8.843   33.623  1   29.09  ? 125 HIS C C   1 
ATOM   5556 O  O   . HIS C 1 129 ? -45.136 8.561   34.319  1   30.4   ? 125 HIS C O   1 
ATOM   5557 C  CB  . HIS C 1 129 ? -46.153 9.782   31.251  1   24.55  ? 125 HIS C CB  1 
ATOM   5558 C  CG  . HIS C 1 129 ? -44.971 10.685  31.474  1   29.31  ? 125 HIS C CG  1 
ATOM   5559 N  ND1 . HIS C 1 129 ? -44.803 11.499  32.584  1   27.13  ? 125 HIS C ND1 1 
ATOM   5560 C  CD2 . HIS C 1 129 ? -43.867 10.87   30.703  1   28.45  ? 125 HIS C CD2 1 
ATOM   5561 C  CE1 . HIS C 1 129 ? -43.661 12.162  32.468  1   27.26  ? 125 HIS C CE1 1 
ATOM   5562 N  NE2 . HIS C 1 129 ? -43.078 11.799  31.329  1   28.3   ? 125 HIS C NE2 1 
ATOM   5563 N  N   . ARG C 1 130 ? -47.214 9.452   34.101  1   27.27  ? 126 ARG C N   1 
ATOM   5564 C  CA  . ARG C 1 130 ? -47.476 9.638   35.523  1   26.46  ? 126 ARG C CA  1 
ATOM   5565 C  C   . ARG C 1 130 ? -46.718 10.824  36.124  1   27.38  ? 126 ARG C C   1 
ATOM   5566 O  O   . ARG C 1 130 ? -46.869 11.103  37.311  1   29.85  ? 126 ARG C O   1 
ATOM   5567 C  CB  . ARG C 1 130 ? -47.205 8.354   36.316  1   22.65  ? 126 ARG C CB  1 
ATOM   5568 C  CG  . ARG C 1 130 ? -48.179 7.24    35.971  1   20.39  ? 126 ARG C CG  1 
ATOM   5569 C  CD  . ARG C 1 130 ? -48.244 6.183   37.048  1   19.75  ? 126 ARG C CD  1 
ATOM   5570 N  NE  . ARG C 1 130 ? -46.923 5.598   37.3    1   19.42  ? 126 ARG C NE  1 
ATOM   5571 C  CZ  . ARG C 1 130 ? -46.719 4.66    38.222  1   20.55  ? 126 ARG C CZ  1 
ATOM   5572 N  NH1 . ARG C 1 130 ? -47.757 4.085   38.821  1   18.79  ? 126 ARG C NH1 1 
ATOM   5573 N  NH2 . ARG C 1 130 ? -45.482 4.29    38.534  1   20.98  ? 126 ARG C NH2 1 
ATOM   5574 N  N   . ASP C 1 131 ? -45.938 11.557  35.328  1   25.36  ? 127 ASP C N   1 
ATOM   5575 C  CA  . ASP C 1 131 ? -45.322 12.749  35.88   1   25.17  ? 127 ASP C CA  1 
ATOM   5576 C  C   . ASP C 1 131 ? -45.309 13.859  34.828  1   24.78  ? 127 ASP C C   1 
ATOM   5577 O  O   . ASP C 1 131 ? -44.326 14.586  34.7    1   24.87  ? 127 ASP C O   1 
ATOM   5578 C  CB  . ASP C 1 131 ? -43.946 12.464  36.461  1   23.69  ? 127 ASP C CB  1 
ATOM   5579 C  CG  . ASP C 1 131 ? -43.399 13.507  37.438  1   30.07  ? 127 ASP C CG  1 
ATOM   5580 O  OD1 . ASP C 1 131 ? -44.206 14.293  38.035  1   27.5   ? 127 ASP C OD1 1 
ATOM   5581 O  OD2 . ASP C 1 131 ? -42.148 13.538  37.597  1   32.24  ? 127 ASP C OD2 1 
ATOM   5582 N  N   . LEU C 1 132 ? -46.406 14.005  34.087  1   23.2   ? 128 LEU C N   1 
ATOM   5583 C  CA  . LEU C 1 132 ? -46.428 15.032  33.058  1   24.99  ? 128 LEU C CA  1 
ATOM   5584 C  C   . LEU C 1 132 ? -46.518 16.386  33.747  1   27.34  ? 128 LEU C C   1 
ATOM   5585 O  O   . LEU C 1 132 ? -47.411 16.61   34.558  1   31.6   ? 128 LEU C O   1 
ATOM   5586 C  CB  . LEU C 1 132 ? -47.537 14.821  32.026  1   21.36  ? 128 LEU C CB  1 
ATOM   5587 C  CG  . LEU C 1 132 ? -47.396 13.555  31.169  1   19.95  ? 128 LEU C CG  1 
ATOM   5588 C  CD1 . LEU C 1 132 ? -48.658 13.346  30.38   1   19.98  ? 128 LEU C CD1 1 
ATOM   5589 C  CD2 . LEU C 1 132 ? -46.173 13.55   30.25   1   17.6   ? 128 LEU C CD2 1 
ATOM   5590 N  N   . LYS C 1 133 ? -45.536 17.241  33.46   1   27.31  ? 129 LYS C N   1 
ATOM   5591 C  CA  . LYS C 1 133 ? -45.477 18.602  33.961  1   27.88  ? 129 LYS C CA  1 
ATOM   5592 C  C   . LYS C 1 133 ? -44.447 19.377  33.139  1   30.32  ? 129 LYS C C   1 
ATOM   5593 O  O   . LYS C 1 133 ? -43.574 18.787  32.498  1   29.7   ? 129 LYS C O   1 
ATOM   5594 C  CB  . LYS C 1 133 ? -45.15  18.67   35.456  1   25.3   ? 129 LYS C CB  1 
ATOM   5595 C  CG  . LYS C 1 133 ? -43.878 17.944  35.828  1   25.28  ? 129 LYS C CG  1 
ATOM   5596 C  CD  . LYS C 1 133 ? -43.473 18.237  37.258  1   25.04  ? 129 LYS C CD  1 
ATOM   5597 C  CE  . LYS C 1 133 ? -42.349 17.318  37.613  1   27.96  ? 129 LYS C CE  1 
ATOM   5598 N  NZ  . LYS C 1 133 ? -41.887 17.666  38.955  1   25.58  ? 129 LYS C NZ  1 
ATOM   5599 N  N   . PRO C 1 134 ? -44.504 20.73   33.153  1   30.95  ? 130 PRO C N   1 
ATOM   5600 C  CA  . PRO C 1 134 ? -43.702 21.533  32.23   1   28.86  ? 130 PRO C CA  1 
ATOM   5601 C  C   . PRO C 1 134 ? -42.224 21.163  32.27   1   25.82  ? 130 PRO C C   1 
ATOM   5602 O  O   . PRO C 1 134 ? -41.577 21.071  31.226  1   24.3   ? 130 PRO C O   1 
ATOM   5603 C  CB  . PRO C 1 134 ? -43.955 22.95   32.72   1   29.34  ? 130 PRO C CB  1 
ATOM   5604 C  CG  . PRO C 1 134 ? -45.319 22.877  33.35   1   31.11  ? 130 PRO C CG  1 
ATOM   5605 C  CD  . PRO C 1 134 ? -45.344 21.538  34.052  1   30.06  ? 130 PRO C CD  1 
ATOM   5606 N  N   . GLN C 1 135 ? -41.72  20.941  33.489  1   24.83  ? 131 GLN C N   1 
ATOM   5607 C  CA  . GLN C 1 135 ? -40.323 20.63   33.766  1   23.12  ? 131 GLN C CA  1 
ATOM   5608 C  C   . GLN C 1 135 ? -39.866 19.365  33.046  1   23.3   ? 131 GLN C C   1 
ATOM   5609 O  O   . GLN C 1 135 ? -38.68  19.232  32.808  1   25.68  ? 131 GLN C O   1 
ATOM   5610 C  CB  . GLN C 1 135 ? -40.089 20.326  35.241  1   22.41  ? 131 GLN C CB  1 
ATOM   5611 C  CG  . GLN C 1 135 ? -40.279 21.516  36.17   1   27.41  ? 131 GLN C CG  1 
ATOM   5612 C  CD  . GLN C 1 135 ? -41.717 21.895  36.483  1   32.63  ? 131 GLN C CD  1 
ATOM   5613 O  OE1 . GLN C 1 135 ? -42.71  21.3    36.024  1   34.54  ? 131 GLN C OE1 1 
ATOM   5614 N  NE2 . GLN C 1 135 ? -41.834 22.963  37.258  1   36.33  ? 131 GLN C NE2 1 
ATOM   5615 N  N   . ASN C 1 136 ? -40.788 18.442  32.722  1   22.99  ? 132 ASN C N   1 
ATOM   5616 C  CA  . ASN C 1 136 ? -40.466 17.159  32.113  1   21.63  ? 132 ASN C CA  1 
ATOM   5617 C  C   . ASN C 1 136 ? -40.739 17.198  30.605  1   20.93  ? 132 ASN C C   1 
ATOM   5618 O  O   . ASN C 1 136 ? -40.749 16.165  29.935  1   20.68  ? 132 ASN C O   1 
ATOM   5619 C  CB  . ASN C 1 136 ? -41.171 16.021  32.847  1   21.6   ? 132 ASN C CB  1 
ATOM   5620 C  CG  . ASN C 1 136 ? -40.726 15.876  34.287  1   24.74  ? 132 ASN C CG  1 
ATOM   5621 O  OD1 . ASN C 1 136 ? -39.697 16.436  34.708  1   27.33  ? 132 ASN C OD1 1 
ATOM   5622 N  ND2 . ASN C 1 136 ? -41.483 15.124  35.07   1   22.44  ? 132 ASN C ND2 1 
ATOM   5623 N  N   . LEU C 1 137 ? -40.969 18.392  30.055  1   20.54  ? 133 LEU C N   1 
ATOM   5624 C  CA  . LEU C 1 137 ? -41.256 18.49   28.633  1   22.5   ? 133 LEU C CA  1 
ATOM   5625 C  C   . LEU C 1 137 ? -40.145 19.316  27.996  1   24.2   ? 133 LEU C C   1 
ATOM   5626 O  O   . LEU C 1 137 ? -39.863 20.415  28.481  1   24.22  ? 133 LEU C O   1 
ATOM   5627 C  CB  . LEU C 1 137 ? -42.629 19.13   28.428  1   23.26  ? 133 LEU C CB  1 
ATOM   5628 C  CG  . LEU C 1 137 ? -43.814 18.4    29.062  1   24.66  ? 133 LEU C CG  1 
ATOM   5629 C  CD1 . LEU C 1 137 ? -45.093 19.168  28.794  1   25.24  ? 133 LEU C CD1 1 
ATOM   5630 C  CD2 . LEU C 1 137 ? -43.887 16.984  28.537  1   23.75  ? 133 LEU C CD2 1 
ATOM   5631 N  N   . LEU C 1 138 ? -39.547 18.787  26.912  1   23.98  ? 134 LEU C N   1 
ATOM   5632 C  CA  . LEU C 1 138 ? -38.339 19.368  26.339  1   25.87  ? 134 LEU C CA  1 
ATOM   5633 C  C   . LEU C 1 138 ? -38.612 19.975  24.962  1   28.47  ? 134 LEU C C   1 
ATOM   5634 O  O   . LEU C 1 138 ? -39.167 19.325  24.078  1   34.12  ? 134 LEU C O   1 
ATOM   5635 C  CB  . LEU C 1 138 ? -37.251 18.298  26.266  1   24.27  ? 134 LEU C CB  1 
ATOM   5636 C  CG  . LEU C 1 138 ? -36.981 17.54   27.567  1   23.94  ? 134 LEU C CG  1 
ATOM   5637 C  CD1 . LEU C 1 138 ? -35.815 16.611  27.342  1   26.19  ? 134 LEU C CD1 1 
ATOM   5638 C  CD2 . LEU C 1 138 ? -36.732 18.482  28.725  1   20.85  ? 134 LEU C CD2 1 
ATOM   5639 N  N   . ILE C 1 139 ? -38.182 21.224  24.773  1   26.24  ? 135 ILE C N   1 
ATOM   5640 C  CA  . ILE C 1 139 ? -38.285 21.885  23.484  1   26.65  ? 135 ILE C CA  1 
ATOM   5641 C  C   . ILE C 1 139 ? -36.879 22.045  22.905  1   25.98  ? 135 ILE C C   1 
ATOM   5642 O  O   . ILE C 1 139 ? -35.913 22.212  23.639  1   25.39  ? 135 ILE C O   1 
ATOM   5643 C  CB  . ILE C 1 139 ? -38.962 23.258  23.659  1   25.32  ? 135 ILE C CB  1 
ATOM   5644 C  CG1 . ILE C 1 139 ? -38.154 24.167  24.578  1   26.9   ? 135 ILE C CG1 1 
ATOM   5645 C  CG2 . ILE C 1 139 ? -40.388 23.099  24.175  1   25.45  ? 135 ILE C CG2 1 
ATOM   5646 C  CD1 . ILE C 1 139 ? -38.42  25.652  24.402  1   28.51  ? 135 ILE C CD1 1 
ATOM   5647 N  N   . ASN C 1 140 ? -36.778 22.028  21.581  1   26.9   ? 136 ASN C N   1 
ATOM   5648 C  CA  . ASN C 1 140 ? -35.589 22.517  20.896  1   31.16  ? 136 ASN C CA  1 
ATOM   5649 C  C   . ASN C 1 140 ? -35.893 23.841  20.191  1   33.85  ? 136 ASN C C   1 
ATOM   5650 O  O   . ASN C 1 140 ? -36.977 24.421  20.348  1   40.26  ? 136 ASN C O   1 
ATOM   5651 C  CB  . ASN C 1 140 ? -35.035 21.483  19.919  1   29.81  ? 136 ASN C CB  1 
ATOM   5652 C  CG  . ASN C 1 140 ? -36.024 21.079  18.84   1   28.31  ? 136 ASN C CG  1 
ATOM   5653 O  OD1 . ASN C 1 140 ? -36.908 21.847  18.441  1   25.19  ? 136 ASN C OD1 1 
ATOM   5654 N  ND2 . ASN C 1 140 ? -35.873 19.874  18.318  1   27.99  ? 136 ASN C ND2 1 
ATOM   5655 N  N   . THR C 1 141 ? -34.916 24.288  19.39   1   33.65  ? 137 THR C N   1 
ATOM   5656 C  CA  . THR C 1 141 ? -34.962 25.553  18.662  1   34.98  ? 137 THR C CA  1 
ATOM   5657 C  C   . THR C 1 141 ? -35.883 25.473  17.444  1   37.19  ? 137 THR C C   1 
ATOM   5658 O  O   . THR C 1 141 ? -36.198 26.501  16.848  1   42.89  ? 137 THR C O   1 
ATOM   5659 C  CB  . THR C 1 141 ? -33.564 25.952  18.181  1   32.57  ? 137 THR C CB  1 
ATOM   5660 O  OG1 . THR C 1 141 ? -33.073 24.899  17.353  1   36.34  ? 137 THR C OG1 1 
ATOM   5661 C  CG2 . THR C 1 141 ? -32.594 26.253  19.303  1   29.26  ? 137 THR C CG2 1 
ATOM   5662 N  N   . GLU C 1 142 ? -36.275 24.262  17.039  1   37.1   ? 138 GLU C N   1 
ATOM   5663 C  CA  . GLU C 1 142 ? -36.908 24.088  15.743  1   39.94  ? 138 GLU C CA  1 
ATOM   5664 C  C   . GLU C 1 142 ? -38.408 23.83   15.854  1   38.16  ? 138 GLU C C   1 
ATOM   5665 O  O   . GLU C 1 142 ? -39.026 23.451  14.877  1   40.85  ? 138 GLU C O   1 
ATOM   5666 C  CB  . GLU C 1 142 ? -36.183 22.994  14.962  1   45.94  ? 138 GLU C CB  1 
ATOM   5667 C  CG  . GLU C 1 142 ? -34.707 23.315  14.749  1   59.29  ? 138 GLU C CG  1 
ATOM   5668 C  CD  . GLU C 1 142 ? -34.115 22.881  13.416  1   68.8   ? 138 GLU C CD  1 
ATOM   5669 O  OE1 . GLU C 1 142 ? -34.416 21.755  12.963  1   77.51  ? 138 GLU C OE1 1 
ATOM   5670 O  OE2 . GLU C 1 142 ? -33.333 23.668  12.836  1   70.52  ? 138 GLU C OE2 1 
ATOM   5671 N  N   . GLY C 1 143 ? -38.983 24.013  17.041  1   39.61  ? 139 GLY C N   1 
ATOM   5672 C  CA  . GLY C 1 143 ? -40.422 23.986  17.223  1   35.51  ? 139 GLY C CA  1 
ATOM   5673 C  C   . GLY C 1 143 ? -40.949 22.63   17.685  1   35.44  ? 139 GLY C C   1 
ATOM   5674 O  O   . GLY C 1 143 ? -42.161 22.413  17.654  1   37.89  ? 139 GLY C O   1 
ATOM   5675 N  N   . ALA C 1 144 ? -40.056 21.735  18.134  1   34.05  ? 140 ALA C N   1 
ATOM   5676 C  CA  . ALA C 1 144 ? -40.474 20.41   18.59   1   31.24  ? 140 ALA C CA  1 
ATOM   5677 C  C   . ALA C 1 144 ? -40.597 20.39   20.114  1   29.61  ? 140 ALA C C   1 
ATOM   5678 O  O   . ALA C 1 144 ? -39.844 21.105  20.794  1   28.69  ? 140 ALA C O   1 
ATOM   5679 C  CB  . ALA C 1 144 ? -39.501 19.351  18.103  1   27.59  ? 140 ALA C CB  1 
ATOM   5680 N  N   . ILE C 1 145 ? -41.555 19.591  20.628  1   28.02  ? 141 ILE C N   1 
ATOM   5681 C  CA  . ILE C 1 145 ? -41.632 19.314  22.064  1   30.86  ? 141 ILE C CA  1 
ATOM   5682 C  C   . ILE C 1 145 ? -41.634 17.801  22.308  1   27.77  ? 141 ILE C C   1 
ATOM   5683 O  O   . ILE C 1 145 ? -42.171 17.05   21.508  1   27.49  ? 141 ILE C O   1 
ATOM   5684 C  CB  . ILE C 1 145 ? -42.834 20.011  22.739  1   31.52  ? 141 ILE C CB  1 
ATOM   5685 C  CG1 . ILE C 1 145 ? -42.744 19.91   24.256  1   31     ? 141 ILE C CG1 1 
ATOM   5686 C  CG2 . ILE C 1 145 ? -44.164 19.444  22.226  1   30.78  ? 141 ILE C CG2 1 
ATOM   5687 C  CD1 . ILE C 1 145 ? -43.65  20.876  24.997  1   33.02  ? 141 ILE C CD1 1 
ATOM   5688 N  N   . LYS C 1 146 ? -41.044 17.357  23.425  1   26.5   ? 142 LYS C N   1 
ATOM   5689 C  CA  . LYS C 1 146 ? -40.903 15.932  23.692  1   25.8   ? 142 LYS C CA  1 
ATOM   5690 C  C   . LYS C 1 146 ? -41.171 15.612  25.16   1   25.32  ? 142 LYS C C   1 
ATOM   5691 O  O   . LYS C 1 146 ? -40.732 16.352  26.048  1   28.54  ? 142 LYS C O   1 
ATOM   5692 C  CB  . LYS C 1 146 ? -39.515 15.403  23.316  1   26.08  ? 142 LYS C CB  1 
ATOM   5693 C  CG  . LYS C 1 146 ? -39.03  15.762  21.921  1   25.79  ? 142 LYS C CG  1 
ATOM   5694 C  CD  . LYS C 1 146 ? -37.958 14.81   21.413  1   25.9   ? 142 LYS C CD  1 
ATOM   5695 C  CE  . LYS C 1 146 ? -37.331 15.209  20.111  1   27.85  ? 142 LYS C CE  1 
ATOM   5696 N  NZ  . LYS C 1 146 ? -36.37  14.188  19.666  1   28.51  ? 142 LYS C NZ  1 
ATOM   5697 N  N   . LEU C 1 147 ? -41.92  14.523  25.396  1   23.36  ? 143 LEU C N   1 
ATOM   5698 C  CA  . LEU C 1 147 ? -42.091 13.969  26.726  1   23.34  ? 143 LEU C CA  1 
ATOM   5699 C  C   . LEU C 1 147 ? -40.72  13.507  27.177  1   25.79  ? 143 LEU C C   1 
ATOM   5700 O  O   . LEU C 1 147 ? -40.002 12.893  26.392  1   31.71  ? 143 LEU C O   1 
ATOM   5701 C  CB  . LEU C 1 147 ? -43.009 12.754  26.735  1   22.01  ? 143 LEU C CB  1 
ATOM   5702 C  CG  . LEU C 1 147 ? -44.376 12.883  26.067  1   24.14  ? 143 LEU C CG  1 
ATOM   5703 C  CD1 . LEU C 1 147 ? -45.249 11.762  26.54   1   26.72  ? 143 LEU C CD1 1 
ATOM   5704 C  CD2 . LEU C 1 147 ? -45.011 14.151  26.485  1   26.71  ? 143 LEU C CD2 1 
ATOM   5705 N  N   . ALA C 1 148 ? -40.375 13.805  28.429  1   24.42  ? 144 ALA C N   1 
ATOM   5706 C  CA  . ALA C 1 148 ? -39.128 13.331  29.005  1   24.6   ? 144 ALA C CA  1 
ATOM   5707 C  C   . ALA C 1 148 ? -39.388 12.871  30.435  1   25.31  ? 144 ALA C C   1 
ATOM   5708 O  O   . ALA C 1 148 ? -40.538 12.842  30.866  1   24.77  ? 144 ALA C O   1 
ATOM   5709 C  CB  . ALA C 1 148 ? -38.053 14.398  28.922  1   20.8   ? 144 ALA C CB  1 
ATOM   5710 N  N   . ASP C 1 149 ? -38.306 12.518  31.134  1   27.12  ? 145 ASP C N   1 
ATOM   5711 C  CA  . ASP C 1 149 ? -38.304 11.956  32.475  1   28.21  ? 145 ASP C CA  1 
ATOM   5712 C  C   . ASP C 1 149 ? -39.371 10.877  32.659  1   25.74  ? 145 ASP C C   1 
ATOM   5713 O  O   . ASP C 1 149 ? -40.456 11.16   33.155  1   26.1   ? 145 ASP C O   1 
ATOM   5714 C  CB  . ASP C 1 149 ? -38.367 13.011  33.561  1   29.62  ? 145 ASP C CB  1 
ATOM   5715 C  CG  . ASP C 1 149 ? -37.969 12.449  34.921  1   36.02  ? 145 ASP C CG  1 
ATOM   5716 O  OD1 . ASP C 1 149 ? -38.216 11.235  35.175  1   33.06  ? 145 ASP C OD1 1 
ATOM   5717 O  OD2 . ASP C 1 149 ? -37.421 13.222  35.727  1   41.35  ? 145 ASP C OD2 1 
ATOM   5718 N  N   . PHE C 1 150 ? -39.015 9.64    32.315  1   25.21  ? 146 PHE C N   1 
ATOM   5719 C  CA  . PHE C 1 150 ? -39.872 8.475   32.473  1   24.85  ? 146 PHE C CA  1 
ATOM   5720 C  C   . PHE C 1 150 ? -39.534 7.729   33.761  1   25.69  ? 146 PHE C C   1 
ATOM   5721 O  O   . PHE C 1 150 ? -39.775 6.535   33.887  1   28.97  ? 146 PHE C O   1 
ATOM   5722 C  CB  . PHE C 1 150 ? -39.701 7.564   31.255  1   23.79  ? 146 PHE C CB  1 
ATOM   5723 C  CG  . PHE C 1 150 ? -40.511 8.076   30.083  1   23.49  ? 146 PHE C CG  1 
ATOM   5724 C  CD1 . PHE C 1 150 ? -40.107 9.208   29.39   1   22.61  ? 146 PHE C CD1 1 
ATOM   5725 C  CD2 . PHE C 1 150 ? -41.691 7.439   29.711  1   23.11  ? 146 PHE C CD2 1 
ATOM   5726 C  CE1 . PHE C 1 150 ? -40.86  9.678   28.321  1   23.5   ? 146 PHE C CE1 1 
ATOM   5727 C  CE2 . PHE C 1 150 ? -42.445 7.915   28.653  1   24.07  ? 146 PHE C CE2 1 
ATOM   5728 C  CZ  . PHE C 1 150 ? -42.029 9.042   27.959  1   24.18  ? 146 PHE C CZ  1 
ATOM   5729 N  N   . GLY C 1 151 ? -38.984 8.455   34.728  1   29.02  ? 147 GLY C N   1 
ATOM   5730 C  CA  . GLY C 1 151 ? -38.591 7.88    36.003  1   30.47  ? 147 GLY C CA  1 
ATOM   5731 C  C   . GLY C 1 151 ? -39.784 7.349   36.791  1   30.52  ? 147 GLY C C   1 
ATOM   5732 O  O   . GLY C 1 151 ? -39.608 6.416   37.557  1   36.18  ? 147 GLY C O   1 
ATOM   5733 N  N   . LEU C 1 152 ? -40.984 7.903   36.555  1   29.98  ? 148 LEU C N   1 
ATOM   5734 C  CA  . LEU C 1 152 ? -42.182 7.484   37.259  1   29.81  ? 148 LEU C CA  1 
ATOM   5735 C  C   . LEU C 1 152 ? -43.119 6.734   36.33   1   28.7   ? 148 LEU C C   1 
ATOM   5736 O  O   . LEU C 1 152 ? -44.262 6.482   36.696  1   35.23  ? 148 LEU C O   1 
ATOM   5737 C  CB  . LEU C 1 152 ? -42.916 8.67    37.87   1   35.87  ? 148 LEU C CB  1 
ATOM   5738 C  CG  . LEU C 1 152 ? -42.155 9.405   38.972  1   47.77  ? 148 LEU C CG  1 
ATOM   5739 C  CD1 . LEU C 1 152 ? -42.911 10.657  39.411  1   51.32  ? 148 LEU C CD1 1 
ATOM   5740 C  CD2 . LEU C 1 152 ? -41.885 8.432   40.11   1   54.17  ? 148 LEU C CD2 1 
ATOM   5741 N  N   . ALA C 1 153 ? -42.65  6.393   35.131  1   25.15  ? 149 ALA C N   1 
ATOM   5742 C  CA  . ALA C 1 153 ? -43.519 5.744   34.162  1   24.1   ? 149 ALA C CA  1 
ATOM   5743 C  C   . ALA C 1 153 ? -43.8   4.302   34.593  1   23.52  ? 149 ALA C C   1 
ATOM   5744 O  O   . ALA C 1 153 ? -43.203 3.8     35.532  1   24.15  ? 149 ALA C O   1 
ATOM   5745 C  CB  . ALA C 1 153 ? -42.896 5.838   32.787  1   21.85  ? 149 ALA C CB  1 
ATOM   5746 N  N   . ARG C 1 154 ? -44.717 3.62    33.908  1   23.9   ? 150 ARG C N   1 
ATOM   5747 C  CA  . ARG C 1 154 ? -45.097 2.284   34.342  1   25.82  ? 150 ARG C CA  1 
ATOM   5748 C  C   . ARG C 1 154 ? -45.806 1.552   33.2    1   26.23  ? 150 ARG C C   1 
ATOM   5749 O  O   . ARG C 1 154 ? -46.705 2.08    32.547  1   27.38  ? 150 ARG C O   1 
ATOM   5750 C  CB  . ARG C 1 154 ? -45.831 2.419   35.688  1   25.25  ? 150 ARG C CB  1 
ATOM   5751 C  CG  . ARG C 1 154 ? -47.025 1.492   35.856  1   26.77  ? 150 ARG C CG  1 
ATOM   5752 C  CD  . ARG C 1 154 ? -46.688 0.124   36.376  1   28.13  ? 150 ARG C CD  1 
ATOM   5753 N  NE  . ARG C 1 154 ? -46.557 0.135   37.837  1   25.97  ? 150 ARG C NE  1 
ATOM   5754 C  CZ  . ARG C 1 154 ? -46.516 -0.974  38.566  1   24.6   ? 150 ARG C CZ  1 
ATOM   5755 N  NH1 . ARG C 1 154 ? -46.494 -0.891  39.888  1   22.94  ? 150 ARG C NH1 1 
ATOM   5756 N  NH2 . ARG C 1 154 ? -46.531 -2.16   37.966  1   23.67  ? 150 ARG C NH2 1 
ATOM   5757 N  N   . ALA C 1 155 ? -45.363 0.327   32.933  1   26.24  ? 151 ALA C N   1 
ATOM   5758 C  CA  . ALA C 1 155 ? -46.004 -0.481  31.911  1   25.65  ? 151 ALA C CA  1 
ATOM   5759 C  C   . ALA C 1 155 ? -47.281 -1.068  32.512  1   27.42  ? 151 ALA C C   1 
ATOM   5760 O  O   . ALA C 1 155 ? -47.22  -1.769  33.523  1   29.82  ? 151 ALA C O   1 
ATOM   5761 C  CB  . ALA C 1 155 ? -45.031 -1.544  31.426  1   21.6   ? 151 ALA C CB  1 
ATOM   5762 N  N   . PHE C 1 156 ? -48.445 -0.742  31.936  1   26.72  ? 152 PHE C N   1 
ATOM   5763 C  CA  . PHE C 1 156 ? -49.7   -1.245  32.486  1   27.5   ? 152 PHE C CA  1 
ATOM   5764 C  C   . PHE C 1 156 ? -50.189 -2.469  31.697  1   32.27  ? 152 PHE C C   1 
ATOM   5765 O  O   . PHE C 1 156 ? -49.687 -2.772  30.607  1   34.36  ? 152 PHE C O   1 
ATOM   5766 C  CB  . PHE C 1 156 ? -50.75  -0.132  32.583  1   24.45  ? 152 PHE C CB  1 
ATOM   5767 C  CG  . PHE C 1 156 ? -51.233 0.461   31.269  1   24.02  ? 152 PHE C CG  1 
ATOM   5768 C  CD1 . PHE C 1 156 ? -52.341 -0.065  30.593  1   23.42  ? 152 PHE C CD1 1 
ATOM   5769 C  CD2 . PHE C 1 156 ? -50.593 1.569   30.722  1   23.68  ? 152 PHE C CD2 1 
ATOM   5770 C  CE1 . PHE C 1 156 ? -52.782 0.489   29.39   1   22.43  ? 152 PHE C CE1 1 
ATOM   5771 C  CE2 . PHE C 1 156 ? -51.043 2.129   29.527  1   24.19  ? 152 PHE C CE2 1 
ATOM   5772 C  CZ  . PHE C 1 156 ? -52.133 1.586   28.857  1   22.49  ? 152 PHE C CZ  1 
ATOM   5773 N  N   . GLY C 1 157 ? -51.172 -3.184  32.267  1   28.22  ? 153 GLY C N   1 
ATOM   5774 C  CA  . GLY C 1 157 ? -51.881 -4.228  31.545  1   25.68  ? 153 GLY C CA  1 
ATOM   5775 C  C   . GLY C 1 157 ? -53.34  -3.817  31.351  1   26.44  ? 153 GLY C C   1 
ATOM   5776 O  O   . GLY C 1 157 ? -53.779 -2.794  31.899  1   28.26  ? 153 GLY C O   1 
ATOM   5777 N  N   . VAL C 1 158 ? -54.088 -4.61   30.576  1   23.83  ? 154 VAL C N   1 
ATOM   5778 C  CA  . VAL C 1 158 ? -55.467 -4.276  30.258  1   24.1   ? 154 VAL C CA  1 
ATOM   5779 C  C   . VAL C 1 158 ? -56.336 -5.393  30.82   1   23.83  ? 154 VAL C C   1 
ATOM   5780 O  O   . VAL C 1 158 ? -56.086 -6.542  30.483  1   27.29  ? 154 VAL C O   1 
ATOM   5781 C  CB  . VAL C 1 158 ? -55.624 -4.15   28.728  1   25.45  ? 154 VAL C CB  1 
ATOM   5782 C  CG1 . VAL C 1 158 ? -57.073 -3.955  28.307  1   26.59  ? 154 VAL C CG1 1 
ATOM   5783 C  CG2 . VAL C 1 158 ? -54.719 -3.081  28.115  1   23.41  ? 154 VAL C CG2 1 
ATOM   5784 N  N   . PRO C 1 159 ? -57.293 -5.148  31.753  1   23.81  ? 155 PRO C N   1 
ATOM   5785 C  CA  . PRO C 1 159 ? -57.464 -3.847  32.418  1   23.74  ? 155 PRO C CA  1 
ATOM   5786 C  C   . PRO C 1 159 ? -56.332 -3.509  33.387  1   25.12  ? 155 PRO C C   1 
ATOM   5787 O  O   . PRO C 1 159 ? -55.552 -4.379  33.793  1   24.9   ? 155 PRO C O   1 
ATOM   5788 C  CB  . PRO C 1 159 ? -58.776 -4.033  33.225  1   23.5   ? 155 PRO C CB  1 
ATOM   5789 C  CG  . PRO C 1 159 ? -58.853 -5.524  33.506  1   21.84  ? 155 PRO C CG  1 
ATOM   5790 C  CD  . PRO C 1 159 ? -58.247 -6.162  32.257  1   21.57  ? 155 PRO C CD  1 
ATOM   5791 N  N   . VAL C 1 160 ? -56.305 -2.244  33.815  1   26.2   ? 156 VAL C N   1 
ATOM   5792 C  CA  . VAL C 1 160 ? -55.324 -1.829  34.799  1   25.53  ? 156 VAL C CA  1 
ATOM   5793 C  C   . VAL C 1 160 ? -55.64  -2.54   36.114  1   26.8   ? 156 VAL C C   1 
ATOM   5794 O  O   . VAL C 1 160 ? -56.798 -2.869  36.385  1   25.52  ? 156 VAL C O   1 
ATOM   5795 C  CB  . VAL C 1 160 ? -55.307 -0.298  34.94   1   23.5   ? 156 VAL C CB  1 
ATOM   5796 C  CG1 . VAL C 1 160 ? -54.963 0.377   33.614  1   25.21  ? 156 VAL C CG1 1 
ATOM   5797 C  CG2 . VAL C 1 160 ? -56.612 0.239   35.491  1   22.23  ? 156 VAL C CG2 1 
ATOM   5798 N  N   . ARG C 1 161 ? -54.583 -2.654  36.915  1   28.4   ? 157 ARG C N   1 
ATOM   5799 C  CA  . ARG C 1 161 ? -54.701 -3.16   38.295  1   31.25  ? 157 ARG C CA  1 
ATOM   5800 C  C   . ARG C 1 161 ? -54.293 -1.961  39.161  1   29.32  ? 157 ARG C C   1 
ATOM   5801 O  O   . ARG C 1 161 ? -54.067 -0.885  38.597  1   31.93  ? 157 ARG C O   1 
ATOM   5802 C  CB  . ARG C 1 161 ? -53.784 -4.369  38.493  1   30.78  ? 157 ARG C CB  1 
ATOM   5803 C  CG  . ARG C 1 161 ? -52.299 -4.107  38.685  1   36.94  ? 157 ARG C CG  1 
ATOM   5804 C  CD  . ARG C 1 161 ? -51.594 -5.302  39.297  1   42.73  ? 157 ARG C CD  1 
ATOM   5805 N  NE  . ARG C 1 161 ? -50.55  -4.912  40.25   1   48.3   ? 157 ARG C NE  1 
ATOM   5806 C  CZ  . ARG C 1 161 ? -49.326 -4.543  39.908  1   51.81  ? 157 ARG C CZ  1 
ATOM   5807 N  NH1 . ARG C 1 161 ? -48.686 -3.633  40.62   1   49.75  ? 157 ARG C NH1 1 
ATOM   5808 N  NH2 . ARG C 1 161 ? -48.749 -5.086  38.854  1   51.35  ? 157 ARG C NH2 1 
ATOM   5809 N  N   . THR C 1 162 ? -54.213 -2.131  40.471  1   26.81  ? 158 THR C N   1 
ATOM   5810 C  CA  . THR C 1 162 ? -53.789 -1.047  41.357  1   28.29  ? 158 THR C CA  1 
ATOM   5811 C  C   . THR C 1 162 ? -52.282 -0.809  41.201  1   29.48  ? 158 THR C C   1 
ATOM   5812 O  O   . THR C 1 162 ? -51.49  -1.755  41.321  1   31.98  ? 158 THR C O   1 
ATOM   5813 C  CB  . THR C 1 162 ? -54.138 -1.369  42.821  1   26.95  ? 158 THR C CB  1 
ATOM   5814 O  OG1 . THR C 1 162 ? -55.529 -1.64   42.9    1   28.18  ? 158 THR C OG1 1 
ATOM   5815 C  CG2 . THR C 1 162 ? -53.836 -0.241  43.792  1   22.68  ? 158 THR C CG2 1 
ATOM   5816 N  N   . TYR C 1 163 ? -51.901 0.458   40.953  1   26.28  ? 159 TYR C N   1 
ATOM   5817 C  CA  . TYR C 1 163 ? -50.507 0.874   40.909  1   24.55  ? 159 TYR C CA  1 
ATOM   5818 C  C   . TYR C 1 163 ? -50.23  1.858   42.041  1   27.5   ? 159 TYR C C   1 
ATOM   5819 O  O   . TYR C 1 163 ? -51.02  1.983   42.974  1   31.09  ? 159 TYR C O   1 
ATOM   5820 C  CB  . TYR C 1 163 ? -50.235 1.494   39.544  1   23.7   ? 159 TYR C CB  1 
ATOM   5821 C  CG  . TYR C 1 163 ? -50.616 0.594   38.382  1   23.39  ? 159 TYR C CG  1 
ATOM   5822 C  CD1 . TYR C 1 163 ? -50.26  -0.746  38.375  1   23.67  ? 159 TYR C CD1 1 
ATOM   5823 C  CD2 . TYR C 1 163 ? -51.336 1.089   37.303  1   22.81  ? 159 TYR C CD2 1 
ATOM   5824 C  CE1 . TYR C 1 163 ? -50.591 -1.563  37.31   1   27.21  ? 159 TYR C CE1 1 
ATOM   5825 C  CE2 . TYR C 1 163 ? -51.674 0.278   36.235  1   23.58  ? 159 TYR C CE2 1 
ATOM   5826 C  CZ  . TYR C 1 163 ? -51.302 -1.058  36.232  1   26.98  ? 159 TYR C CZ  1 
ATOM   5827 O  OH  . TYR C 1 163 ? -51.62  -1.911  35.191  1   27.31  ? 159 TYR C OH  1 
HETATM 5828 N  N   . TPO C 1 164 ? -49.08  2.538   41.985  1   28.72  ? 160 TPO C N   1 
HETATM 5829 C  CA  . TPO C 1 164 ? -48.637 3.366   43.098  1   29.7   ? 160 TPO C CA  1 
HETATM 5830 C  CB  . TPO C 1 164 ? -47.168 3.74    42.882  1   27.58  ? 160 TPO C CB  1 
HETATM 5831 C  CG2 . TPO C 1 164 ? -46.562 4.474   44.057  1   26.67  ? 160 TPO C CG2 1 
HETATM 5832 O  OG1 . TPO C 1 164 ? -46.447 2.477   42.723  1   25.73  ? 160 TPO C OG1 1 
HETATM 5833 P  P   . TPO C 1 164 ? -45.759 2.167   41.299  1   23.96  ? 160 TPO C P   1 
HETATM 5834 O  O1P . TPO C 1 164 ? -46.923 1.896   40.364  1   25.46  ? 160 TPO C O1P 1 
HETATM 5835 O  O2P . TPO C 1 164 ? -44.844 0.964   41.518  1   21.77  ? 160 TPO C O2P 1 
HETATM 5836 O  O3P . TPO C 1 164 ? -45     3.419   40.909  1   21.51  ? 160 TPO C O3P 1 
HETATM 5837 C  C   . TPO C 1 164 ? -49.564 4.579   43.245  1   31.56  ? 160 TPO C C   1 
HETATM 5838 O  O   . TPO C 1 164 ? -49.97  5.158   42.243  1   26.57  ? 160 TPO C O   1 
ATOM   5839 N  N   . HIS C 1 165 ? -49.894 4.974   44.484  1   35.66  ? 161 HIS C N   1 
ATOM   5840 C  CA  . HIS C 1 165 ? -50.792 6.106   44.675  1   42.96  ? 161 HIS C CA  1 
ATOM   5841 C  C   . HIS C 1 165 ? -50.051 7.45    44.611  1   45.71  ? 161 HIS C C   1 
ATOM   5842 O  O   . HIS C 1 165 ? -50.576 8.456   44.116  1   40.08  ? 161 HIS C O   1 
ATOM   5843 C  CB  . HIS C 1 165 ? -51.59  5.938   45.967  1   49.5   ? 161 HIS C CB  1 
ATOM   5844 C  CG  . HIS C 1 165 ? -52.579 7.044   46.16   1   69.34  ? 161 HIS C CG  1 
ATOM   5845 N  ND1 . HIS C 1 165 ? -52.351 8.124   46.992  1   72.46  ? 161 HIS C ND1 1 
ATOM   5846 C  CD2 . HIS C 1 165 ? -53.793 7.243   45.617  1   77.3   ? 161 HIS C CD2 1 
ATOM   5847 C  CE1 . HIS C 1 165 ? -53.402 8.933   46.967  1   78.25  ? 161 HIS C CE1 1 
ATOM   5848 N  NE2 . HIS C 1 165 ? -54.29  8.419   46.136  1   84.62  ? 161 HIS C NE2 1 
ATOM   5849 N  N   . GLU C 1 166 ? -48.82  7.472   45.134  1   50.62  ? 162 GLU C N   1 
ATOM   5850 C  CA  . GLU C 1 166 ? -48.048 8.704   45.197  1   56.91  ? 162 GLU C CA  1 
ATOM   5851 C  C   . GLU C 1 166 ? -47.456 8.936   43.81   1   53.81  ? 162 GLU C C   1 
ATOM   5852 O  O   . GLU C 1 166 ? -46.277 8.657   43.578  1   55.49  ? 162 GLU C O   1 
ATOM   5853 C  CB  . GLU C 1 166 ? -47.077 8.763   46.39   1   62.6   ? 162 GLU C CB  1 
ATOM   5854 C  CG  . GLU C 1 166 ? -46.591 7.404   46.907  1   71.7   ? 162 GLU C CG  1 
ATOM   5855 C  CD  . GLU C 1 166 ? -47.584 6.583   47.729  1   77.5   ? 162 GLU C CD  1 
ATOM   5856 O  OE1 . GLU C 1 166 ? -48.032 7.097   48.781  1   76.87  ? 162 GLU C OE1 1 
ATOM   5857 O  OE2 . GLU C 1 166 ? -47.921 5.435   47.345  1   76.31  ? 162 GLU C OE2 1 
ATOM   5858 N  N   . VAL C 1 167 ? -48.309 9.398   42.882  1   42.3   ? 163 VAL C N   1 
ATOM   5859 C  CA  . VAL C 1 167 ? -47.855 9.65    41.522  1   40.02  ? 163 VAL C CA  1 
ATOM   5860 C  C   . VAL C 1 167 ? -48.368 11.011  41.074  1   34.72  ? 163 VAL C C   1 
ATOM   5861 O  O   . VAL C 1 167 ? -49.45  11.433  41.482  1   32.94  ? 163 VAL C O   1 
ATOM   5862 C  CB  . VAL C 1 167 ? -48.183 8.564   40.467  1   39.61  ? 163 VAL C CB  1 
ATOM   5863 C  CG1 . VAL C 1 167 ? -47.473 7.264   40.793  1   35.22  ? 163 VAL C CG1 1 
ATOM   5864 C  CG2 . VAL C 1 167 ? -49.684 8.335   40.284  1   33.85  ? 163 VAL C CG2 1 
ATOM   5865 N  N   . VAL C 1 168 ? -47.585 11.644  40.196  1   31.51  ? 164 VAL C N   1 
ATOM   5866 C  CA  . VAL C 1 168 ? -47.944 12.911  39.578  1   30.77  ? 164 VAL C CA  1 
ATOM   5867 C  C   . VAL C 1 168 ? -47.67  14.01   40.604  1   31.3   ? 164 VAL C C   1 
ATOM   5868 O  O   . VAL C 1 168 ? -48.115 13.926  41.746  1   32.2   ? 164 VAL C O   1 
ATOM   5869 C  CB  . VAL C 1 168 ? -49.368 13.003  38.979  1   28.62  ? 164 VAL C CB  1 
ATOM   5870 C  CG1 . VAL C 1 168 ? -49.526 14.246  38.127  1   25.51  ? 164 VAL C CG1 1 
ATOM   5871 C  CG2 . VAL C 1 168 ? -49.755 11.782  38.137  1   29.7   ? 164 VAL C CG2 1 
ATOM   5872 N  N   . THR C 1 169 ? -46.885 15.016  40.207  1   30.14  ? 165 THR C N   1 
ATOM   5873 C  CA  . THR C 1 169 ? -46.741 16.236  40.985  1   29.98  ? 165 THR C CA  1 
ATOM   5874 C  C   . THR C 1 169 ? -48.137 16.784  41.294  1   26.52  ? 165 THR C C   1 
ATOM   5875 O  O   . THR C 1 169 ? -49.01  16.799  40.42   1   28.93  ? 165 THR C O   1 
ATOM   5876 C  CB  . THR C 1 169 ? -45.878 17.207  40.176  1   31.91  ? 165 THR C CB  1 
ATOM   5877 O  OG1 . THR C 1 169 ? -44.748 16.378  39.908  1   33.38  ? 165 THR C OG1 1 
ATOM   5878 C  CG2 . THR C 1 169 ? -45.488 18.448  40.965  1   30.81  ? 165 THR C CG2 1 
ATOM   5879 N  N   . LEU C 1 170 ? -48.319 17.245  42.532  1   21.95  ? 166 LEU C N   1 
ATOM   5880 C  CA  . LEU C 1 170 ? -49.615 17.65   43.065  1   23.88  ? 166 LEU C CA  1 
ATOM   5881 C  C   . LEU C 1 170 ? -50.441 18.476  42.068  1   25.74  ? 166 LEU C C   1 
ATOM   5882 O  O   . LEU C 1 170 ? -51.605 18.17   41.8    1   26.72  ? 166 LEU C O   1 
ATOM   5883 C  CB  . LEU C 1 170 ? -49.392 18.425  44.36   1   21.25  ? 166 LEU C CB  1 
ATOM   5884 C  CG  . LEU C 1 170 ? -50.662 18.721  45.158  1   22.54  ? 166 LEU C CG  1 
ATOM   5885 C  CD1 . LEU C 1 170 ? -51.381 17.427  45.535  1   21.3   ? 166 LEU C CD1 1 
ATOM   5886 C  CD2 . LEU C 1 170 ? -50.364 19.538  46.415  1   20.8   ? 166 LEU C CD2 1 
ATOM   5887 N  N   . TRP C 1 171 ? -49.838 19.548  41.541  1   26.6   ? 167 TRP C N   1 
ATOM   5888 C  CA  . TRP C 1 171 ? -50.557 20.52   40.734  1   27.47  ? 167 TRP C CA  1 
ATOM   5889 C  C   . TRP C 1 171 ? -51.218 19.871  39.52   1   26     ? 167 TRP C C   1 
ATOM   5890 O  O   . TRP C 1 171 ? -52.189 20.414  39.014  1   26.05  ? 167 TRP C O   1 
ATOM   5891 C  CB  . TRP C 1 171 ? -49.627 21.655  40.287  1   27.3   ? 167 TRP C CB  1 
ATOM   5892 C  CG  . TRP C 1 171 ? -49.141 22.542  41.392  1   28.15  ? 167 TRP C CG  1 
ATOM   5893 C  CD1 . TRP C 1 171 ? -49.477 22.487  42.713  1   30.7   ? 167 TRP C CD1 1 
ATOM   5894 C  CD2 . TRP C 1 171 ? -48.257 23.666  41.24   1   29.45  ? 167 TRP C CD2 1 
ATOM   5895 N  NE1 . TRP C 1 171 ? -48.855 23.492  43.402  1   29.33  ? 167 TRP C NE1 1 
ATOM   5896 C  CE2 . TRP C 1 171 ? -48.102 24.233  42.528  1   30.79  ? 167 TRP C CE2 1 
ATOM   5897 C  CE3 . TRP C 1 171 ? -47.584 24.242  40.153  1   30.66  ? 167 TRP C CE3 1 
ATOM   5898 C  CZ2 . TRP C 1 171 ? -47.3   25.355  42.751  1   29.16  ? 167 TRP C CZ2 1 
ATOM   5899 C  CZ3 . TRP C 1 171 ? -46.797 25.352  40.374  1   30.46  ? 167 TRP C CZ3 1 
ATOM   5900 C  CH2 . TRP C 1 171 ? -46.66  25.895  41.656  1   29.81  ? 167 TRP C CH2 1 
ATOM   5901 N  N   . TYR C 1 172 ? -50.675 18.735  39.057  1   25.23  ? 168 TYR C N   1 
ATOM   5902 C  CA  . TYR C 1 172 ? -51.071 18.119  37.795  1   25.4   ? 168 TYR C CA  1 
ATOM   5903 C  C   . TYR C 1 172 ? -51.739 16.784  38.097  1   26.28  ? 168 TYR C C   1 
ATOM   5904 O  O   . TYR C 1 172 ? -51.985 15.981  37.191  1   27.25  ? 168 TYR C O   1 
ATOM   5905 C  CB  . TYR C 1 172 ? -49.854 17.933  36.875  1   25.02  ? 168 TYR C CB  1 
ATOM   5906 C  CG  . TYR C 1 172 ? -49.089 19.231  36.658  1   24.79  ? 168 TYR C CG  1 
ATOM   5907 C  CD1 . TYR C 1 172 ? -48.188 19.7    37.603  1   23.77  ? 168 TYR C CD1 1 
ATOM   5908 C  CD2 . TYR C 1 172 ? -49.364 20.044  35.57   1   25.01  ? 168 TYR C CD2 1 
ATOM   5909 C  CE1 . TYR C 1 172 ? -47.563 20.927  37.454  1   24.28  ? 168 TYR C CE1 1 
ATOM   5910 C  CE2 . TYR C 1 172 ? -48.751 21.275  35.413  1   25.32  ? 168 TYR C CE2 1 
ATOM   5911 C  CZ  . TYR C 1 172 ? -47.838 21.716  36.35   1   26.41  ? 168 TYR C CZ  1 
ATOM   5912 O  OH  . TYR C 1 172 ? -47.203 22.913  36.156  1   28.65  ? 168 TYR C OH  1 
ATOM   5913 N  N   . ARG C 1 173 ? -52.043 16.565  39.382  1   24.7   ? 169 ARG C N   1 
ATOM   5914 C  CA  . ARG C 1 173 ? -52.651 15.316  39.805  1   23.62  ? 169 ARG C CA  1 
ATOM   5915 C  C   . ARG C 1 173 ? -54.158 15.346  39.554  1   25.05  ? 169 ARG C C   1 
ATOM   5916 O  O   . ARG C 1 173 ? -54.856 16.29   39.927  1   24.27  ? 169 ARG C O   1 
ATOM   5917 C  CB  . ARG C 1 173 ? -52.333 15.052  41.275  1   21.47  ? 169 ARG C CB  1 
ATOM   5918 C  CG  . ARG C 1 173 ? -52.723 13.644  41.69   1   22.82  ? 169 ARG C CG  1 
ATOM   5919 C  CD  . ARG C 1 173 ? -52.307 13.395  43.119  1   25.4   ? 169 ARG C CD  1 
ATOM   5920 N  NE  . ARG C 1 173 ? -50.851 13.505  43.27   1   26.12  ? 169 ARG C NE  1 
ATOM   5921 C  CZ  . ARG C 1 173 ? -50.207 13.822  44.392  1   23.9   ? 169 ARG C CZ  1 
ATOM   5922 N  NH1 . ARG C 1 173 ? -50.857 14.046  45.52   1   21.5   ? 169 ARG C NH1 1 
ATOM   5923 N  NH2 . ARG C 1 173 ? -48.898 13.934  44.359  1   23.19  ? 169 ARG C NH2 1 
ATOM   5924 N  N   . ALA C 1 174 ? -54.642 14.26   38.939  1   26.76  ? 170 ALA C N   1 
ATOM   5925 C  CA  . ALA C 1 174 ? -56.03  14.082  38.536  1   23.52  ? 170 ALA C CA  1 
ATOM   5926 C  C   . ALA C 1 174 ? -56.895 13.876  39.767  1   23.11  ? 170 ALA C C   1 
ATOM   5927 O  O   . ALA C 1 174 ? -56.443 13.33   40.77   1   25.12  ? 170 ALA C O   1 
ATOM   5928 C  CB  . ALA C 1 174 ? -56.141 12.891  37.617  1   20.63  ? 170 ALA C CB  1 
ATOM   5929 N  N   . PRO C 1 175 ? -58.175 14.269  39.711  1   21.72  ? 171 PRO C N   1 
ATOM   5930 C  CA  . PRO C 1 175 ? -59.063 14.096  40.854  1   24.74  ? 171 PRO C CA  1 
ATOM   5931 C  C   . PRO C 1 175 ? -59.265 12.65   41.299  1   27.45  ? 171 PRO C C   1 
ATOM   5932 O  O   . PRO C 1 175 ? -59.471 12.4    42.486  1   28.88  ? 171 PRO C O   1 
ATOM   5933 C  CB  . PRO C 1 175 ? -60.357 14.795  40.414  1   24.62  ? 171 PRO C CB  1 
ATOM   5934 C  CG  . PRO C 1 175 ? -60.273 14.824  38.898  1   22.01  ? 171 PRO C CG  1 
ATOM   5935 C  CD  . PRO C 1 175 ? -58.808 14.941  38.578  1   20.71  ? 171 PRO C CD  1 
ATOM   5936 N  N   . GLU C 1 176 ? -59.19  11.702  40.358  1   26.78  ? 172 GLU C N   1 
ATOM   5937 C  CA  . GLU C 1 176 ? -59.367 10.308  40.728  1   27.04  ? 172 GLU C CA  1 
ATOM   5938 C  C   . GLU C 1 176 ? -58.24  9.858   41.657  1   28.92  ? 172 GLU C C   1 
ATOM   5939 O  O   . GLU C 1 176 ? -58.486 9.046   42.539  1   30.1   ? 172 GLU C O   1 
ATOM   5940 C  CB  . GLU C 1 176 ? -59.588 9.355   39.554  1   25.08  ? 172 GLU C CB  1 
ATOM   5941 C  CG  . GLU C 1 176 ? -58.471 9.351   38.515  1   26.06  ? 172 GLU C CG  1 
ATOM   5942 C  CD  . GLU C 1 176 ? -58.572 10.318  37.335  1   27     ? 172 GLU C CD  1 
ATOM   5943 O  OE1 . GLU C 1 176 ? -57.975 9.979   36.276  1   22.22  ? 172 GLU C OE1 1 
ATOM   5944 O  OE2 . GLU C 1 176 ? -59.21  11.411  37.474  1   26.3   ? 172 GLU C OE2 1 
ATOM   5945 N  N   . ILE C 1 177 ? -57.014 10.384  41.493  1   30.25  ? 173 ILE C N   1 
ATOM   5946 C  CA  . ILE C 1 177 ? -55.931 10      42.402  1   29.19  ? 173 ILE C CA  1 
ATOM   5947 C  C   . ILE C 1 177 ? -56.115 10.679  43.763  1   30.63  ? 173 ILE C C   1 
ATOM   5948 O  O   . ILE C 1 177 ? -55.855 10.091  44.818  1   29.19  ? 173 ILE C O   1 
ATOM   5949 C  CB  . ILE C 1 177 ? -54.541 10.286  41.81   1   26.62  ? 173 ILE C CB  1 
ATOM   5950 C  CG1 . ILE C 1 177 ? -54.331 9.606   40.478  1   30.25  ? 173 ILE C CG1 1 
ATOM   5951 C  CG2 . ILE C 1 177 ? -53.448 9.876   42.783  1   24.19  ? 173 ILE C CG2 1 
ATOM   5952 C  CD1 . ILE C 1 177 ? -52.971 9.885   39.862  1   35.6   ? 173 ILE C CD1 1 
ATOM   5953 N  N   . LEU C 1 178 ? -56.554 11.941  43.719  1   31.25  ? 174 LEU C N   1 
ATOM   5954 C  CA  . LEU C 1 178 ? -56.708 12.751  44.915  1   30.07  ? 174 LEU C CA  1 
ATOM   5955 C  C   . LEU C 1 178 ? -57.776 12.158  45.829  1   29.74  ? 174 LEU C C   1 
ATOM   5956 O  O   . LEU C 1 178 ? -57.599 12.152  47.034  1   30.16  ? 174 LEU C O   1 
ATOM   5957 C  CB  . LEU C 1 178 ? -57.028 14.181  44.489  1   31.52  ? 174 LEU C CB  1 
ATOM   5958 C  CG  . LEU C 1 178 ? -55.853 14.954  43.882  1   33.63  ? 174 LEU C CG  1 
ATOM   5959 C  CD1 . LEU C 1 178 ? -56.378 16.216  43.204  1   36.24  ? 174 LEU C CD1 1 
ATOM   5960 C  CD2 . LEU C 1 178 ? -54.812 15.293  44.945  1   32.66  ? 174 LEU C CD2 1 
ATOM   5961 N  N   . LEU C 1 179 ? -58.851 11.608  45.248  1   30.03  ? 175 LEU C N   1 
ATOM   5962 C  CA  . LEU C 1 179 ? -59.918 10.969  46.001  1   27.72  ? 175 LEU C CA  1 
ATOM   5963 C  C   . LEU C 1 179 ? -59.597 9.512   46.338  1   29.03  ? 175 LEU C C   1 
ATOM   5964 O  O   . LEU C 1 179 ? -60.471 8.819   46.857  1   30.37  ? 175 LEU C O   1 
ATOM   5965 C  CB  . LEU C 1 179 ? -61.201 11.096  45.192  1   27.68  ? 175 LEU C CB  1 
ATOM   5966 C  CG  . LEU C 1 179 ? -61.697 12.528  44.966  1   29.63  ? 175 LEU C CG  1 
ATOM   5967 C  CD1 . LEU C 1 179 ? -62.966 12.572  44.145  1   30.38  ? 175 LEU C CD1 1 
ATOM   5968 C  CD2 . LEU C 1 179 ? -61.904 13.252  46.282  1   28.69  ? 175 LEU C CD2 1 
ATOM   5969 N  N   . GLY C 1 180 ? -58.364 9.055   46.05   1   28.17  ? 176 GLY C N   1 
ATOM   5970 C  CA  . GLY C 1 180 ? -57.826 7.793   46.545  1   30     ? 176 GLY C CA  1 
ATOM   5971 C  C   . GLY C 1 180 ? -58.487 6.563   45.92   1   31.76  ? 176 GLY C C   1 
ATOM   5972 O  O   . GLY C 1 180 ? -58.65  5.54    46.59   1   31.83  ? 176 GLY C O   1 
ATOM   5973 N  N   . CYS C 1 181 ? -58.841 6.677   44.632  1   30     ? 177 CYS C N   1 
ATOM   5974 C  CA  . CYS C 1 181 ? -59.578 5.653   43.912  1   31.07  ? 177 CYS C CA  1 
ATOM   5975 C  C   . CYS C 1 181 ? -58.703 4.422   43.743  1   29.3   ? 177 CYS C C   1 
ATOM   5976 O  O   . CYS C 1 181 ? -57.483 4.537   43.721  1   26.53  ? 177 CYS C O   1 
ATOM   5977 C  CB  . CYS C 1 181 ? -60.01  6.12    42.526  1   36.57  ? 177 CYS C CB  1 
ATOM   5978 S  SG  . CYS C 1 181 ? -61.483 7.182   42.528  1   50.78  ? 177 CYS C SG  1 
ATOM   5979 N  N   . LYS C 1 182 ? -59.347 3.257   43.619  1   29.3   ? 178 LYS C N   1 
ATOM   5980 C  CA  . LYS C 1 182 ? -58.62  2       43.547  1   32.1   ? 178 LYS C CA  1 
ATOM   5981 C  C   . LYS C 1 182 ? -57.813 1.901   42.246  1   29.92  ? 178 LYS C C   1 
ATOM   5982 O  O   . LYS C 1 182 ? -56.683 1.421   42.264  1   28.97  ? 178 LYS C O   1 
ATOM   5983 C  CB  . LYS C 1 182 ? -59.589 0.822   43.703  1   37.36  ? 178 LYS C CB  1 
ATOM   5984 C  CG  . LYS C 1 182 ? -58.93  -0.484  44.164  1   42.99  ? 178 LYS C CG  1 
ATOM   5985 C  CD  . LYS C 1 182 ? -59.847 -1.702  44.141  1   46.18  ? 178 LYS C CD  1 
ATOM   5986 C  CE  . LYS C 1 182 ? -59.161 -3.004  44.439  1   45.57  ? 178 LYS C CE  1 
ATOM   5987 N  NZ  . LYS C 1 182 ? -60.086 -4.142  44.386  1   43     ? 178 LYS C NZ  1 
ATOM   5988 N  N   . TYR C 1 183 ? -58.417 2.322   41.127  1   26.55  ? 179 TYR C N   1 
ATOM   5989 C  CA  . TYR C 1 183 ? -57.8   2.196   39.824  1   26.7   ? 179 TYR C CA  1 
ATOM   5990 C  C   . TYR C 1 183 ? -57.748 3.539   39.102  1   27     ? 179 TYR C C   1 
ATOM   5991 O  O   . TYR C 1 183 ? -58.695 4.319   39.134  1   28.25  ? 179 TYR C O   1 
ATOM   5992 C  CB  . TYR C 1 183 ? -58.622 1.276   38.923  1   29.57  ? 179 TYR C CB  1 
ATOM   5993 C  CG  . TYR C 1 183 ? -58.9   -0.134  39.419  1   31.24  ? 179 TYR C CG  1 
ATOM   5994 C  CD1 . TYR C 1 183 ? -57.862 -1.04   39.622  1   33.43  ? 179 TYR C CD1 1 
ATOM   5995 C  CD2 . TYR C 1 183 ? -60.2   -0.575  39.621  1   30.53  ? 179 TYR C CD2 1 
ATOM   5996 C  CE1 . TYR C 1 183 ? -58.098 -2.34   40.047  1   32.16  ? 179 TYR C CE1 1 
ATOM   5997 C  CE2 . TYR C 1 183 ? -60.447 -1.866  40.055  1   33.17  ? 179 TYR C CE2 1 
ATOM   5998 C  CZ  . TYR C 1 183 ? -59.402 -2.756  40.258  1   33.58  ? 179 TYR C CZ  1 
ATOM   5999 O  OH  . TYR C 1 183 ? -59.675 -4.031  40.681  1   37.35  ? 179 TYR C OH  1 
ATOM   6000 N  N   . TYR C 1 184 ? -56.629 3.78    38.413  1   26.26  ? 180 TYR C N   1 
ATOM   6001 C  CA  . TYR C 1 184 ? -56.493 4.895   37.493  1   25.56  ? 180 TYR C CA  1 
ATOM   6002 C  C   . TYR C 1 184 ? -55.789 4.409   36.229  1   25.96  ? 180 TYR C C   1 
ATOM   6003 O  O   . TYR C 1 184 ? -55.242 3.309   36.212  1   28.2   ? 180 TYR C O   1 
ATOM   6004 C  CB  . TYR C 1 184 ? -55.733 6.041   38.157  1   26.58  ? 180 TYR C CB  1 
ATOM   6005 C  CG  . TYR C 1 184 ? -54.288 5.714   38.519  1   28.4   ? 180 TYR C CG  1 
ATOM   6006 C  CD1 . TYR C 1 184 ? -53.276 5.749   37.562  1   25.67  ? 180 TYR C CD1 1 
ATOM   6007 C  CD2 . TYR C 1 184 ? -53.933 5.42    39.835  1   27.99  ? 180 TYR C CD2 1 
ATOM   6008 C  CE1 . TYR C 1 184 ? -51.963 5.471   37.901  1   27.13  ? 180 TYR C CE1 1 
ATOM   6009 C  CE2 . TYR C 1 184 ? -52.62  5.149   40.185  1   25.69  ? 180 TYR C CE2 1 
ATOM   6010 C  CZ  . TYR C 1 184 ? -51.635 5.166   39.215  1   26.59  ? 180 TYR C CZ  1 
ATOM   6011 O  OH  . TYR C 1 184 ? -50.344 4.863   39.554  1   26.89  ? 180 TYR C OH  1 
ATOM   6012 N  N   . SER C 1 185 ? -55.807 5.244   35.18   1   26     ? 181 SER C N   1 
ATOM   6013 C  CA  . SER C 1 185 ? -55.481 4.818   33.827  1   27.41  ? 181 SER C CA  1 
ATOM   6014 C  C   . SER C 1 185 ? -54.888 5.961   33.003  1   25.75  ? 181 SER C C   1 
ATOM   6015 O  O   . SER C 1 185 ? -54.494 7       33.544  1   27.45  ? 181 SER C O   1 
ATOM   6016 C  CB  . SER C 1 185 ? -56.711 4.244   33.145  1   29.99  ? 181 SER C CB  1 
ATOM   6017 O  OG  . SER C 1 185 ? -56.381 3.642   31.896  1   32.97  ? 181 SER C OG  1 
ATOM   6018 N  N   . THR C 1 186 ? -54.858 5.751   31.682  1   23.84  ? 182 THR C N   1 
ATOM   6019 C  CA  . THR C 1 186 ? -54.395 6.731   30.711  1   26.57  ? 182 THR C CA  1 
ATOM   6020 C  C   . THR C 1 186 ? -55.019 8.104   30.95   1   27.04  ? 182 THR C C   1 
ATOM   6021 O  O   . THR C 1 186 ? -54.42  9.11    30.591  1   27.8   ? 182 THR C O   1 
ATOM   6022 C  CB  . THR C 1 186 ? -54.617 6.274   29.264  1   25.84  ? 182 THR C CB  1 
ATOM   6023 O  OG1 . THR C 1 186 ? -56.021 6.16    29.057  1   27.14  ? 182 THR C OG1 1 
ATOM   6024 C  CG2 . THR C 1 186 ? -53.894 4.982   28.949  1   23.54  ? 182 THR C CG2 1 
ATOM   6025 N  N   . ALA C 1 187 ? -56.205 8.155   31.562  1   29.06  ? 183 ALA C N   1 
ATOM   6026 C  CA  . ALA C 1 187 ? -56.872 9.425   31.836  1   27.89  ? 183 ALA C CA  1 
ATOM   6027 C  C   . ALA C 1 187 ? -56.068 10.351  32.752  1   26.19  ? 183 ALA C C   1 
ATOM   6028 O  O   . ALA C 1 187 ? -56.179 11.555  32.609  1   29.01  ? 183 ALA C O   1 
ATOM   6029 C  CB  . ALA C 1 187 ? -58.281 9.211   32.343  1   27.12  ? 183 ALA C CB  1 
ATOM   6030 N  N   . VAL C 1 188 ? -55.247 9.832   33.666  1   26.21  ? 184 VAL C N   1 
ATOM   6031 C  CA  . VAL C 1 188 ? -54.527 10.712  34.582  1   25.92  ? 184 VAL C CA  1 
ATOM   6032 C  C   . VAL C 1 188 ? -53.498 11.524  33.803  1   26.91  ? 184 VAL C C   1 
ATOM   6033 O  O   . VAL C 1 188 ? -53.131 12.625  34.214  1   29.22  ? 184 VAL C O   1 
ATOM   6034 C  CB  . VAL C 1 188 ? -53.837 10.006  35.764  1   24.34  ? 184 VAL C CB  1 
ATOM   6035 C  CG1 . VAL C 1 188 ? -54.772 9.016   36.437  1   23.69  ? 184 VAL C CG1 1 
ATOM   6036 C  CG2 . VAL C 1 188 ? -52.541 9.329   35.339  1   22.92  ? 184 VAL C CG2 1 
ATOM   6037 N  N   . ASP C 1 189 ? -52.994 10.944  32.712  1   24.95  ? 185 ASP C N   1 
ATOM   6038 C  CA  . ASP C 1 189 ? -52.007 11.639  31.909  1   26.16  ? 185 ASP C CA  1 
ATOM   6039 C  C   . ASP C 1 189 ? -52.702 12.742  31.126  1   26.35  ? 185 ASP C C   1 
ATOM   6040 O  O   . ASP C 1 189 ? -52.118 13.802  30.927  1   30.9   ? 185 ASP C O   1 
ATOM   6041 C  CB  . ASP C 1 189 ? -51.232 10.696  31.001  1   27.22  ? 185 ASP C CB  1 
ATOM   6042 C  CG  . ASP C 1 189 ? -50.134 9.891   31.685  1   29.01  ? 185 ASP C CG  1 
ATOM   6043 O  OD1 . ASP C 1 189 ? -49.701 10.269  32.814  1   26.89  ? 185 ASP C OD1 1 
ATOM   6044 O  OD2 . ASP C 1 189 ? -49.741 8.871   31.095  1   28.04  ? 185 ASP C OD2 1 
ATOM   6045 N  N   . ILE C 1 190 ? -53.937 12.484  30.674  1   22.87  ? 186 ILE C N   1 
ATOM   6046 C  CA  . ILE C 1 190 ? -54.67  13.491  29.933  1   22.98  ? 186 ILE C CA  1 
ATOM   6047 C  C   . ILE C 1 190 ? -54.941 14.683  30.857  1   25.47  ? 186 ILE C C   1 
ATOM   6048 O  O   . ILE C 1 190 ? -54.824 15.838  30.452  1   26.07  ? 186 ILE C O   1 
ATOM   6049 C  CB  . ILE C 1 190 ? -55.954 12.925  29.288  1   22.63  ? 186 ILE C CB  1 
ATOM   6050 C  CG1 . ILE C 1 190 ? -55.658 12.016  28.064  1   22.12  ? 186 ILE C CG1 1 
ATOM   6051 C  CG2 . ILE C 1 190 ? -56.909 14.057  28.898  1   19.68  ? 186 ILE C CG2 1 
ATOM   6052 C  CD1 . ILE C 1 190 ? -55.202 12.778  26.829  1   20.88  ? 186 ILE C CD1 1 
ATOM   6053 N  N   . TRP C 1 191 ? -55.295 14.412  32.115  1   24.3   ? 187 TRP C N   1 
ATOM   6054 C  CA  . TRP C 1 191 ? -55.564 15.475  33.063  1   22.79  ? 187 TRP C CA  1 
ATOM   6055 C  C   . TRP C 1 191 ? -54.383 16.45   33.152  1   25.99  ? 187 TRP C C   1 
ATOM   6056 O  O   . TRP C 1 191 ? -54.553 17.659  32.999  1   26.91  ? 187 TRP C O   1 
ATOM   6057 C  CB  . TRP C 1 191 ? -55.882 14.852  34.419  1   21.12  ? 187 TRP C CB  1 
ATOM   6058 C  CG  . TRP C 1 191 ? -56.172 15.918  35.436  1   22.41  ? 187 TRP C CG  1 
ATOM   6059 C  CD1 . TRP C 1 191 ? -55.255 16.581  36.197  1   20.02  ? 187 TRP C CD1 1 
ATOM   6060 C  CD2 . TRP C 1 191 ? -57.465 16.482  35.746  1   21.56  ? 187 TRP C CD2 1 
ATOM   6061 N  NE1 . TRP C 1 191 ? -55.894 17.486  36.989  1   20.81  ? 187 TRP C NE1 1 
ATOM   6062 C  CE2 . TRP C 1 191 ? -57.242 17.466  36.725  1   20.66  ? 187 TRP C CE2 1 
ATOM   6063 C  CE3 . TRP C 1 191 ? -58.77  16.249  35.3    1   21.4   ? 187 TRP C CE3 1 
ATOM   6064 C  CZ2 . TRP C 1 191 ? -58.285 18.206  37.273  1   20.77  ? 187 TRP C CZ2 1 
ATOM   6065 C  CZ3 . TRP C 1 191 ? -59.804 16.967  35.853  1   21.62  ? 187 TRP C CZ3 1 
ATOM   6066 C  CH2 . TRP C 1 191 ? -59.559 17.943  36.821  1   21.84  ? 187 TRP C CH2 1 
ATOM   6067 N  N   . SER C 1 192 ? -53.177 15.902  33.358  1   26.26  ? 188 SER C N   1 
ATOM   6068 C  CA  . SER C 1 192 ? -51.93  16.646  33.421  1   25.11  ? 188 SER C CA  1 
ATOM   6069 C  C   . SER C 1 192 ? -51.726 17.534  32.189  1   25.67  ? 188 SER C C   1 
ATOM   6070 O  O   . SER C 1 192 ? -51.352 18.696  32.316  1   28.33  ? 188 SER C O   1 
ATOM   6071 C  CB  . SER C 1 192 ? -50.75  15.699  33.624  1   25.14  ? 188 SER C CB  1 
ATOM   6072 O  OG  . SER C 1 192 ? -50.941 14.787  34.698  1   22.2   ? 188 SER C OG  1 
ATOM   6073 N  N   . LEU C 1 193 ? -51.917 16.979  30.988  1   26.01  ? 189 LEU C N   1 
ATOM   6074 C  CA  . LEU C 1 193 ? -51.829 17.749  29.75   1   27.45  ? 189 LEU C CA  1 
ATOM   6075 C  C   . LEU C 1 193 ? -52.871 18.87   29.725  1   27.91  ? 189 LEU C C   1 
ATOM   6076 O  O   . LEU C 1 193 ? -52.634 19.928  29.154  1   29.92  ? 189 LEU C O   1 
ATOM   6077 C  CB  . LEU C 1 193 ? -51.954 16.865  28.506  1   26.64  ? 189 LEU C CB  1 
ATOM   6078 C  CG  . LEU C 1 193 ? -50.748 15.996  28.148  1   27.17  ? 189 LEU C CG  1 
ATOM   6079 C  CD1 . LEU C 1 193 ? -50.87  15.468  26.745  1   25.78  ? 189 LEU C CD1 1 
ATOM   6080 C  CD2 . LEU C 1 193 ? -49.436 16.756  28.28   1   30.37  ? 189 LEU C CD2 1 
ATOM   6081 N  N   . GLY C 1 194 ? -54.053 18.626  30.3    1   26.79  ? 190 GLY C N   1 
ATOM   6082 C  CA  . GLY C 1 194 ? -55.075 19.654  30.357  1   25.37  ? 190 GLY C CA  1 
ATOM   6083 C  C   . GLY C 1 194 ? -54.588 20.837  31.191  1   26.04  ? 190 GLY C C   1 
ATOM   6084 O  O   . GLY C 1 194 ? -54.713 21.993  30.781  1   24.54  ? 190 GLY C O   1 
ATOM   6085 N  N   . CYS C 1 195 ? -54.026 20.516  32.358  1   25.15  ? 191 CYS C N   1 
ATOM   6086 C  CA  . CYS C 1 195 ? -53.385 21.487  33.224  1   27.67  ? 191 CYS C CA  1 
ATOM   6087 C  C   . CYS C 1 195 ? -52.296 22.26   32.462  1   32.48  ? 191 CYS C C   1 
ATOM   6088 O  O   . CYS C 1 195 ? -52.143 23.487  32.619  1   30.07  ? 191 CYS C O   1 
ATOM   6089 C  CB  . CYS C 1 195 ? -52.846 20.774  34.46   1   27.02  ? 191 CYS C CB  1 
ATOM   6090 S  SG  . CYS C 1 195 ? -54.154 19.985  35.444  1   27.48  ? 191 CYS C SG  1 
ATOM   6091 N  N   . ILE C 1 196 ? -51.537 21.527  31.625  1   30.8   ? 192 ILE C N   1 
ATOM   6092 C  CA  . ILE C 1 196 ? -50.412 22.084  30.893  1   28.82  ? 192 ILE C CA  1 
ATOM   6093 C  C   . ILE C 1 196 ? -50.927 22.931  29.72   1   29.75  ? 192 ILE C C   1 
ATOM   6094 O  O   . ILE C 1 196 ? -50.372 23.999  29.419  1   31.36  ? 192 ILE C O   1 
ATOM   6095 C  CB  . ILE C 1 196 ? -49.427 20.966  30.494  1   28.27  ? 192 ILE C CB  1 
ATOM   6096 C  CG1 . ILE C 1 196 ? -48.632 20.483  31.715  1   27.41  ? 192 ILE C CG1 1 
ATOM   6097 C  CG2 . ILE C 1 196 ? -48.477 21.417  29.376  1   26.02  ? 192 ILE C CG2 1 
ATOM   6098 C  CD1 . ILE C 1 196 ? -47.982 19.131  31.518  1   26.98  ? 192 ILE C CD1 1 
ATOM   6099 N  N   . PHE C 1 197 ? -52.007 22.471  29.071  1   24.99  ? 193 PHE C N   1 
ATOM   6100 C  CA  . PHE C 1 197 ? -52.669 23.293  28.073  1   21.62  ? 193 PHE C CA  1 
ATOM   6101 C  C   . PHE C 1 197 ? -52.991 24.677  28.65   1   20.28  ? 193 PHE C C   1 
ATOM   6102 O  O   . PHE C 1 197 ? -52.577 25.681  28.094  1   20.15  ? 193 PHE C O   1 
ATOM   6103 C  CB  . PHE C 1 197 ? -53.856 22.533  27.486  1   20.4   ? 193 PHE C CB  1 
ATOM   6104 C  CG  . PHE C 1 197 ? -54.559 23.247  26.343  1   18.63  ? 193 PHE C CG  1 
ATOM   6105 C  CD1 . PHE C 1 197 ? -53.948 24.296  25.662  1   17.54  ? 193 PHE C CD1 1 
ATOM   6106 C  CD2 . PHE C 1 197 ? -55.824 22.845  25.933  1   17.82  ? 193 PHE C CD2 1 
ATOM   6107 C  CE1 . PHE C 1 197 ? -54.6   24.929  24.611  1   18.34  ? 193 PHE C CE1 1 
ATOM   6108 C  CE2 . PHE C 1 197 ? -56.457 23.481  24.87   1   18.01  ? 193 PHE C CE2 1 
ATOM   6109 C  CZ  . PHE C 1 197 ? -55.845 24.513  24.201  1   17.38  ? 193 PHE C CZ  1 
ATOM   6110 N  N   . ALA C 1 198 ? -53.686 24.729  29.788  1   20.18  ? 194 ALA C N   1 
ATOM   6111 C  CA  . ALA C 1 198 ? -54.051 25.986  30.431  1   21.77  ? 194 ALA C CA  1 
ATOM   6112 C  C   . ALA C 1 198 ? -52.842 26.844  30.814  1   23.41  ? 194 ALA C C   1 
ATOM   6113 O  O   . ALA C 1 198 ? -52.92  28.08   30.801  1   23.47  ? 194 ALA C O   1 
ATOM   6114 C  CB  . ALA C 1 198 ? -54.91  25.715  31.645  1   20.63  ? 194 ALA C CB  1 
ATOM   6115 N  N   . GLU C 1 199 ? -51.757 26.174  31.211  1   23.59  ? 195 GLU C N   1 
ATOM   6116 C  CA  . GLU C 1 199 ? -50.573 26.848  31.711  1   26.69  ? 195 GLU C CA  1 
ATOM   6117 C  C   . GLU C 1 199 ? -49.836 27.54   30.56   1   27.41  ? 195 GLU C C   1 
ATOM   6118 O  O   . GLU C 1 199 ? -49.306 28.647  30.728  1   29.79  ? 195 GLU C O   1 
ATOM   6119 C  CB  . GLU C 1 199 ? -49.704 25.848  32.48   1   26.73  ? 195 GLU C CB  1 
ATOM   6120 C  CG  . GLU C 1 199 ? -48.707 26.498  33.434  1   25.84  ? 195 GLU C CG  1 
ATOM   6121 C  CD  . GLU C 1 199 ? -48.014 25.527  34.376  1   29.9   ? 195 GLU C CD  1 
ATOM   6122 O  OE1 . GLU C 1 199 ? -48.63  24.493  34.674  1   31.84  ? 195 GLU C OE1 1 
ATOM   6123 O  OE2 . GLU C 1 199 ? -46.861 25.776  34.812  1   32.49  ? 195 GLU C OE2 1 
ATOM   6124 N  N   . MET C 1 200 ? -49.782 26.885  29.394  1   25.89  ? 196 MET C N   1 
ATOM   6125 C  CA  . MET C 1 200 ? -49.142 27.499  28.243  1   25.08  ? 196 MET C CA  1 
ATOM   6126 C  C   . MET C 1 200 ? -49.887 28.776  27.855  1   29.23  ? 196 MET C C   1 
ATOM   6127 O  O   . MET C 1 200 ? -49.248 29.776  27.512  1   35.44  ? 196 MET C O   1 
ATOM   6128 C  CB  . MET C 1 200 ? -49.06  26.531  27.069  1   22.86  ? 196 MET C CB  1 
ATOM   6129 C  CG  . MET C 1 200 ? -47.993 25.49   27.247  1   23.91  ? 196 MET C CG  1 
ATOM   6130 S  SD  . MET C 1 200 ? -47.834 24.508  25.745  1   28.4   ? 196 MET C SD  1 
ATOM   6131 C  CE  . MET C 1 200 ? -49.196 23.336  25.722  1   24.41  ? 196 MET C CE  1 
ATOM   6132 N  N   . VAL C 1 201 ? -51.225 28.753  27.994  1   27.45  ? 197 VAL C N   1 
ATOM   6133 C  CA  . VAL C 1 201 ? -52.105 29.838  27.592  1   26.98  ? 197 VAL C CA  1 
ATOM   6134 C  C   . VAL C 1 201 ? -52.002 31.039  28.54   1   29.73  ? 197 VAL C C   1 
ATOM   6135 O  O   . VAL C 1 201 ? -51.995 32.18   28.078  1   33.26  ? 197 VAL C O   1 
ATOM   6136 C  CB  . VAL C 1 201 ? -53.561 29.352  27.489  1   25.32  ? 197 VAL C CB  1 
ATOM   6137 C  CG1 . VAL C 1 201 ? -54.521 30.515  27.278  1   22.66  ? 197 VAL C CG1 1 
ATOM   6138 C  CG2 . VAL C 1 201 ? -53.75  28.289  26.413  1   24.19  ? 197 VAL C CG2 1 
ATOM   6139 N  N   . THR C 1 202 ? -51.967 30.784  29.858  1   31.25  ? 198 THR C N   1 
ATOM   6140 C  CA  . THR C 1 202 ? -51.954 31.826  30.888  1   28.95  ? 198 THR C CA  1 
ATOM   6141 C  C   . THR C 1 202 ? -50.57  31.953  31.541  1   28.96  ? 198 THR C C   1 
ATOM   6142 O  O   . THR C 1 202 ? -50.337 32.898  32.295  1   24.9   ? 198 THR C O   1 
ATOM   6143 C  CB  . THR C 1 202 ? -53.012 31.562  31.965  1   27.15  ? 198 THR C CB  1 
ATOM   6144 O  OG1 . THR C 1 202 ? -52.533 30.474  32.749  1   27.43  ? 198 THR C OG1 1 
ATOM   6145 C  CG2 . THR C 1 202 ? -54.382 31.203  31.419  1   27.37  ? 198 THR C CG2 1 
ATOM   6146 N  N   . ARG C 1 203 ? -49.685 30.964  31.326  1   32.17  ? 199 ARG C N   1 
ATOM   6147 C  CA  . ARG C 1 203 ? -48.34  30.965  31.901  1   37.1   ? 199 ARG C CA  1 
ATOM   6148 C  C   . ARG C 1 203 ? -48.379 30.888  33.434  1   36.89  ? 199 ARG C C   1 
ATOM   6149 O  O   . ARG C 1 203 ? -47.342 30.958  34.082  1   36.84  ? 199 ARG C O   1 
ATOM   6150 C  CB  . ARG C 1 203 ? -47.496 32.138  31.372  1   39.99  ? 199 ARG C CB  1 
ATOM   6151 C  CG  . ARG C 1 203 ? -46.699 31.829  30.114  1   40.5   ? 199 ARG C CG  1 
ATOM   6152 C  CD  . ARG C 1 203 ? -46.506 33.022  29.196  1   46.82  ? 199 ARG C CD  1 
ATOM   6153 N  NE  . ARG C 1 203 ? -47.799 33.518  28.709  1   50.55  ? 199 ARG C NE  1 
ATOM   6154 C  CZ  . ARG C 1 203 ? -48.307 34.705  29.051  1   47.92  ? 199 ARG C CZ  1 
ATOM   6155 N  NH1 . ARG C 1 203 ? -47.541 35.636  29.608  1   38.07  ? 199 ARG C NH1 1 
ATOM   6156 N  NH2 . ARG C 1 203 ? -49.583 34.956  28.809  1   50.99  ? 199 ARG C NH2 1 
ATOM   6157 N  N   . ARG C 1 204 ? -49.578 30.742  34.01   1   37.29  ? 200 ARG C N   1 
ATOM   6158 C  CA  . ARG C 1 204 ? -49.774 30.462  35.424  1   34.52  ? 200 ARG C CA  1 
ATOM   6159 C  C   . ARG C 1 204 ? -50.358 29.059  35.514  1   35.98  ? 200 ARG C C   1 
ATOM   6160 O  O   . ARG C 1 204 ? -51.194 28.704  34.675  1   37.45  ? 200 ARG C O   1 
ATOM   6161 C  CB  . ARG C 1 204 ? -50.761 31.449  36.058  1   32.04  ? 200 ARG C CB  1 
ATOM   6162 C  CG  . ARG C 1 204 ? -50.125 32.791  36.374  1   37.41  ? 200 ARG C CG  1 
ATOM   6163 C  CD  . ARG C 1 204 ? -51.107 33.885  36.771  1   38.5   ? 200 ARG C CD  1 
ATOM   6164 N  NE  . ARG C 1 204 ? -51.767 34.428  35.578  1   41.67  ? 200 ARG C NE  1 
ATOM   6165 C  CZ  . ARG C 1 204 ? -51.76  35.684  35.114  1   43.08  ? 200 ARG C CZ  1 
ATOM   6166 N  NH1 . ARG C 1 204 ? -51.155 36.66   35.753  1   41.37  ? 200 ARG C NH1 1 
ATOM   6167 N  NH2 . ARG C 1 204 ? -52.368 35.974  33.979  1   45.45  ? 200 ARG C NH2 1 
ATOM   6168 N  N   . ALA C 1 205 ? -49.871 28.276  36.492  1   31.76  ? 201 ALA C N   1 
ATOM   6169 C  CA  . ALA C 1 205 ? -50.373 26.933  36.739  1   28.44  ? 201 ALA C CA  1 
ATOM   6170 C  C   . ALA C 1 205 ? -51.866 27.022  37.035  1   26.25  ? 201 ALA C C   1 
ATOM   6171 O  O   . ALA C 1 205 ? -52.298 27.966  37.677  1   25.77  ? 201 ALA C O   1 
ATOM   6172 C  CB  . ALA C 1 205 ? -49.621 26.314  37.89   1   29.18  ? 201 ALA C CB  1 
ATOM   6173 N  N   . LEU C 1 206 ? -52.645 26.051  36.549  1   25.02  ? 202 LEU C N   1 
ATOM   6174 C  CA  . LEU C 1 206 ? -54.096 26.113  36.65   1   23.33  ? 202 LEU C CA  1 
ATOM   6175 C  C   . LEU C 1 206 ? -54.537 25.868  38.092  1   25.63  ? 202 LEU C C   1 
ATOM   6176 O  O   . LEU C 1 206 ? -55.436 26.541  38.566  1   26.58  ? 202 LEU C O   1 
ATOM   6177 C  CB  . LEU C 1 206 ? -54.697 25.083  35.697  1   21.65  ? 202 LEU C CB  1 
ATOM   6178 C  CG  . LEU C 1 206 ? -56.229 25.047  35.602  1   21.38  ? 202 LEU C CG  1 
ATOM   6179 C  CD1 . LEU C 1 206 ? -56.866 26.367  35.121  1   18.26  ? 202 LEU C CD1 1 
ATOM   6180 C  CD2 . LEU C 1 206 ? -56.658 23.856  34.729  1   18.31  ? 202 LEU C CD2 1 
ATOM   6181 N  N   . PHE C 1 207 ? -53.921 24.901  38.786  1   26.22  ? 203 PHE C N   1 
ATOM   6182 C  CA  . PHE C 1 207 ? -54.376 24.52   40.115  1   26.75  ? 203 PHE C CA  1 
ATOM   6183 C  C   . PHE C 1 207 ? -53.174 24.376  41.044  1   27.89  ? 203 PHE C C   1 
ATOM   6184 O  O   . PHE C 1 207 ? -52.748 23.254  41.338  1   31.76  ? 203 PHE C O   1 
ATOM   6185 C  CB  . PHE C 1 207 ? -55.069 23.152  40.058  1   24.66  ? 203 PHE C CB  1 
ATOM   6186 C  CG  . PHE C 1 207 ? -56.284 23.069  39.157  1   23.33  ? 203 PHE C CG  1 
ATOM   6187 C  CD1 . PHE C 1 207 ? -57.316 23.994  39.262  1   21.7   ? 203 PHE C CD1 1 
ATOM   6188 C  CD2 . PHE C 1 207 ? -56.376 22.074  38.186  1   24.83  ? 203 PHE C CD2 1 
ATOM   6189 C  CE1 . PHE C 1 207 ? -58.414 23.926  38.411  1   21.89  ? 203 PHE C CE1 1 
ATOM   6190 C  CE2 . PHE C 1 207 ? -57.49  21.996  37.346  1   24.52  ? 203 PHE C CE2 1 
ATOM   6191 C  CZ  . PHE C 1 207 ? -58.514 22.922  37.468  1   23.67  ? 203 PHE C CZ  1 
ATOM   6192 N  N   . PRO C 1 208 ? -52.574 25.487  41.527  1   27.72  ? 204 PRO C N   1 
ATOM   6193 C  CA  . PRO C 1 208 ? -51.395 25.406  42.396  1   28.58  ? 204 PRO C CA  1 
ATOM   6194 C  C   . PRO C 1 208 ? -51.756 25.207  43.865  1   30.32  ? 204 PRO C C   1 
ATOM   6195 O  O   . PRO C 1 208 ? -51.77  26.165  44.631  1   34.13  ? 204 PRO C O   1 
ATOM   6196 C  CB  . PRO C 1 208 ? -50.763 26.783  42.148  1   27.79  ? 204 PRO C CB  1 
ATOM   6197 C  CG  . PRO C 1 208 ? -51.953 27.711  41.998  1   25.41  ? 204 PRO C CG  1 
ATOM   6198 C  CD  . PRO C 1 208 ? -52.997 26.874  41.265  1   27.02  ? 204 PRO C CD  1 
ATOM   6199 N  N   . GLY C 1 209 ? -52.062 23.964  44.245  1   31.7   ? 205 GLY C N   1 
ATOM   6200 C  CA  . GLY C 1 209 ? -52.479 23.665  45.609  1   30.4   ? 205 GLY C CA  1 
ATOM   6201 C  C   . GLY C 1 209 ? -51.271 23.445  46.512  1   28.4   ? 205 GLY C C   1 
ATOM   6202 O  O   . GLY C 1 209 ? -50.246 22.977  46.046  1   27.94  ? 205 GLY C O   1 
ATOM   6203 N  N   . ASP C 1 210 ? -51.582 23.863  47.889  1   31.5   ? 206 ASP C N   1 
ATOM   6204 C  CA  . ASP C 1 210 ? -50.519 23.683  48.917  1   36.36  ? 206 ASP C CA  1 
ATOM   6205 C  C   . ASP C 1 210 ? -50.643 22.291  49.546  1   35.96  ? 206 ASP C C   1 
ATOM   6206 O  O   . ASP C 1 210 ? -49.647 21.804  50.093  1   39.79  ? 206 ASP C O   1 
ATOM   6207 C  CB  . ASP C 1 210 ? -50.524 24.858  49.879  1   36.65  ? 206 ASP C CB  1 
ATOM   6208 C  CG  . ASP C 1 210 ? -50.024 26.176  49.313  1   44.65  ? 206 ASP C CG  1 
ATOM   6209 O  OD1 . ASP C 1 210 ? -49.393 26.149  48.237  1   46.82  ? 206 ASP C OD1 1 
ATOM   6210 O  OD2 . ASP C 1 210 ? -50.267 27.217  49.957  1   51.45  ? 206 ASP C OD2 1 
ATOM   6211 N  N   . SER C 1 211 ? -51.698 21.588  49.319  1   34.84  ? 207 SER C N   1 
ATOM   6212 C  CA  . SER C 1 211 ? -52.072 20.337  49.969  1   33.25  ? 207 SER C CA  1 
ATOM   6213 C  C   . SER C 1 211 ? -53.117 19.605  49.12   1   35.88  ? 207 SER C C   1 
ATOM   6214 O  O   . SER C 1 211 ? -53.676 20.17   48.174  1   35.11  ? 207 SER C O   1 
ATOM   6215 C  CB  . SER C 1 211 ? -52.543 20.541  51.402  1   28.15  ? 207 SER C CB  1 
ATOM   6216 O  OG  . SER C 1 211 ? -53.796 21.208  51.454  1   26.54  ? 207 SER C OG  1 
ATOM   6217 N  N   . GLU C 1 212 ? -53.383 18.338  49.462  1   37.17  ? 208 GLU C N   1 
ATOM   6218 C  CA  . GLU C 1 212 ? -54.349 17.547  48.713  1   36.9   ? 208 GLU C CA  1 
ATOM   6219 C  C   . GLU C 1 212 ? -55.753 18.122  48.867  1   32.23  ? 208 GLU C C   1 
ATOM   6220 O  O   . GLU C 1 212 ? -56.493 18.231  47.893  1   29.97  ? 208 GLU C O   1 
ATOM   6221 C  CB  . GLU C 1 212 ? -54.344 16.094  49.173  1   39.35  ? 208 GLU C CB  1 
ATOM   6222 C  CG  . GLU C 1 212 ? -53.309 15.248  48.447  1   44.06  ? 208 GLU C CG  1 
ATOM   6223 C  CD  . GLU C 1 212 ? -53.005 13.977  49.216  1   52.11  ? 208 GLU C CD  1 
ATOM   6224 O  OE1 . GLU C 1 212 ? -53.87  13.079  49.243  1   56.89  ? 208 GLU C OE1 1 
ATOM   6225 O  OE2 . GLU C 1 212 ? -51.906 13.904  49.808  1   55.33  ? 208 GLU C OE2 1 
ATOM   6226 N  N   . ILE C 1 213 ? -56.116 18.475  50.103  1   32.95  ? 209 ILE C N   1 
ATOM   6227 C  CA  . ILE C 1 213 ? -57.432 19.045  50.344  1   35.16  ? 209 ILE C CA  1 
ATOM   6228 C  C   . ILE C 1 213 ? -57.556 20.361  49.57   1   34.52  ? 209 ILE C C   1 
ATOM   6229 O  O   . ILE C 1 213 ? -58.6   20.631  48.973  1   38.04  ? 209 ILE C O   1 
ATOM   6230 C  CB  . ILE C 1 213 ? -57.751 19.168  51.847  1   35.3   ? 209 ILE C CB  1 
ATOM   6231 C  CG1 . ILE C 1 213 ? -59.232 19.438  52.088  1   41.74  ? 209 ILE C CG1 1 
ATOM   6232 C  CG2 . ILE C 1 213 ? -56.878 20.213  52.538  1   36.34  ? 209 ILE C CG2 1 
ATOM   6233 C  CD1 . ILE C 1 213 ? -60.144 18.238  51.884  1   42.09  ? 209 ILE C CD1 1 
ATOM   6234 N  N   . ASP C 1 214 ? -56.459 21.129  49.527  1   28.22  ? 210 ASP C N   1 
ATOM   6235 C  CA  . ASP C 1 214 ? -56.433 22.408  48.85   1   25.32  ? 210 ASP C CA  1 
ATOM   6236 C  C   . ASP C 1 214 ? -56.494 22.227  47.336  1   26.73  ? 210 ASP C C   1 
ATOM   6237 O  O   . ASP C 1 214 ? -57.119 23.045  46.662  1   25.3   ? 210 ASP C O   1 
ATOM   6238 C  CB  . ASP C 1 214 ? -55.184 23.185  49.202  1   24.53  ? 210 ASP C CB  1 
ATOM   6239 C  CG  . ASP C 1 214 ? -55.155 24.594  48.637  1   24.77  ? 210 ASP C CG  1 
ATOM   6240 O  OD1 . ASP C 1 214 ? -56.023 25.411  49.06   1   25.67  ? 210 ASP C OD1 1 
ATOM   6241 O  OD2 . ASP C 1 214 ? -54.266 24.852  47.786  1   23.37  ? 210 ASP C OD2 1 
ATOM   6242 N  N   . GLN C 1 215 ? -55.814 21.183  46.826  1   26.79  ? 211 GLN C N   1 
ATOM   6243 C  CA  . GLN C 1 215 ? -55.787 20.853  45.41   1   25.74  ? 211 GLN C CA  1 
ATOM   6244 C  C   . GLN C 1 215 ? -57.201 20.565  44.904  1   26.18  ? 211 GLN C C   1 
ATOM   6245 O  O   . GLN C 1 215 ? -57.572 20.986  43.805  1   29.41  ? 211 GLN C O   1 
ATOM   6246 C  CB  . GLN C 1 215 ? -54.89  19.64   45.179  1   27.55  ? 211 GLN C CB  1 
ATOM   6247 C  CG  . GLN C 1 215 ? -54.602 19.326  43.711  1   28.49  ? 211 GLN C CG  1 
ATOM   6248 C  CD  . GLN C 1 215 ? -53.759 20.367  43.009  1   28.62  ? 211 GLN C CD  1 
ATOM   6249 O  OE1 . GLN C 1 215 ? -52.923 21.025  43.634  1   30.48  ? 211 GLN C OE1 1 
ATOM   6250 N  NE2 . GLN C 1 215 ? -53.984 20.552  41.714  1   27.19  ? 211 GLN C NE2 1 
ATOM   6251 N  N   . LEU C 1 216 ? -57.994 19.872  45.725  1   25.61  ? 212 LEU C N   1 
ATOM   6252 C  CA  . LEU C 1 216 ? -59.362 19.521  45.371  1   27.65  ? 212 LEU C CA  1 
ATOM   6253 C  C   . LEU C 1 216 ? -60.245 20.757  45.286  1   28.8   ? 212 LEU C C   1 
ATOM   6254 O  O   . LEU C 1 216 ? -61.013 20.927  44.335  1   30.51  ? 212 LEU C O   1 
ATOM   6255 C  CB  . LEU C 1 216 ? -59.924 18.579  46.433  1   28.29  ? 212 LEU C CB  1 
ATOM   6256 C  CG  . LEU C 1 216 ? -59.655 17.095  46.189  1   29.29  ? 212 LEU C CG  1 
ATOM   6257 C  CD1 . LEU C 1 216 ? -60.152 16.299  47.376  1   29.95  ? 212 LEU C CD1 1 
ATOM   6258 C  CD2 . LEU C 1 216 ? -60.316 16.656  44.892  1   26.05  ? 212 LEU C CD2 1 
ATOM   6259 N  N   . PHE C 1 217 ? -60.188 21.554  46.354  1   28.03  ? 213 PHE C N   1 
ATOM   6260 C  CA  . PHE C 1 217 ? -60.961 22.776  46.44   1   27.23  ? 213 PHE C CA  1 
ATOM   6261 C  C   . PHE C 1 217 ? -60.644 23.653  45.228  1   27.78  ? 213 PHE C C   1 
ATOM   6262 O  O   . PHE C 1 217 ? -61.556 24.221  44.632  1   28.89  ? 213 PHE C O   1 
ATOM   6263 C  CB  . PHE C 1 217 ? -60.667 23.431  47.793  1   26.16  ? 213 PHE C CB  1 
ATOM   6264 C  CG  . PHE C 1 217 ? -61.234 22.723  49.013  1   25.2   ? 213 PHE C CG  1 
ATOM   6265 C  CD1 . PHE C 1 217 ? -61.881 21.492  48.903  1   25.33  ? 213 PHE C CD1 1 
ATOM   6266 C  CD2 . PHE C 1 217 ? -61.099 23.289  50.272  1   23.38  ? 213 PHE C CD2 1 
ATOM   6267 C  CE1 . PHE C 1 217 ? -62.396 20.858  50.024  1   25.01  ? 213 PHE C CE1 1 
ATOM   6268 C  CE2 . PHE C 1 217 ? -61.607 22.643  51.385  1   24.74  ? 213 PHE C CE2 1 
ATOM   6269 C  CZ  . PHE C 1 217 ? -62.264 21.439  51.265  1   24.33  ? 213 PHE C CZ  1 
ATOM   6270 N  N   . ARG C 1 218 ? -59.36  23.746  44.851  1   26.78  ? 214 ARG C N   1 
ATOM   6271 C  CA  . ARG C 1 218 ? -58.965 24.585  43.732  1   25.01  ? 214 ARG C CA  1 
ATOM   6272 C  C   . ARG C 1 218 ? -59.645 24.093  42.461  1   25.6   ? 214 ARG C C   1 
ATOM   6273 O  O   . ARG C 1 218 ? -60.184 24.885  41.684  1   27.32  ? 214 ARG C O   1 
ATOM   6274 C  CB  . ARG C 1 218 ? -57.445 24.615  43.574  1   23.68  ? 214 ARG C CB  1 
ATOM   6275 C  CG  . ARG C 1 218 ? -56.824 25.664  44.485  1   23.21  ? 214 ARG C CG  1 
ATOM   6276 C  CD  . ARG C 1 218 ? -55.32  25.496  44.475  1   25.51  ? 214 ARG C CD  1 
ATOM   6277 N  NE  . ARG C 1 218 ? -54.781 26.41   45.48   1   28.36  ? 214 ARG C NE  1 
ATOM   6278 C  CZ  . ARG C 1 218 ? -54.629 27.701  45.27   1   29.72  ? 214 ARG C CZ  1 
ATOM   6279 N  NH1 . ARG C 1 218 ? -54.827 28.215  44.062  1   31.56  ? 214 ARG C NH1 1 
ATOM   6280 N  NH2 . ARG C 1 218 ? -54.22  28.454  46.265  1   29.6   ? 214 ARG C NH2 1 
ATOM   6281 N  N   . ILE C 1 219 ? -59.617 22.775  42.275  1   24.11  ? 215 ILE C N   1 
ATOM   6282 C  CA  . ILE C 1 219 ? -60.234 22.174  41.109  1   24.61  ? 215 ILE C CA  1 
ATOM   6283 C  C   . ILE C 1 219 ? -61.742 22.478  41.118  1   28.11  ? 215 ILE C C   1 
ATOM   6284 O  O   . ILE C 1 219 ? -62.298 22.948  40.118  1   28.66  ? 215 ILE C O   1 
ATOM   6285 C  CB  . ILE C 1 219 ? -59.884 20.677  41.083  1   22.63  ? 215 ILE C CB  1 
ATOM   6286 C  CG1 . ILE C 1 219 ? -58.384 20.465  40.838  1   21.58  ? 215 ILE C CG1 1 
ATOM   6287 C  CG2 . ILE C 1 219 ? -60.74  19.924  40.068  1   21.25  ? 215 ILE C CG2 1 
ATOM   6288 C  CD1 . ILE C 1 219 ? -57.9   19.049  41.12   1   22.52  ? 215 ILE C CD1 1 
ATOM   6289 N  N   . PHE C 1 220 ? -62.387 22.257  42.275  1   28     ? 216 PHE C N   1 
ATOM   6290 C  CA  . PHE C 1 220 ? -63.825 22.384  42.432  1   25.57  ? 216 PHE C CA  1 
ATOM   6291 C  C   . PHE C 1 220 ? -64.278 23.822  42.227  1   25.85  ? 216 PHE C C   1 
ATOM   6292 O  O   . PHE C 1 220 ? -65.315 24.053  41.611  1   27.12  ? 216 PHE C O   1 
ATOM   6293 C  CB  . PHE C 1 220 ? -64.224 21.968  43.844  1   26.39  ? 216 PHE C CB  1 
ATOM   6294 C  CG  . PHE C 1 220 ? -64.074 20.489  44.138  1   27.05  ? 216 PHE C CG  1 
ATOM   6295 C  CD1 . PHE C 1 220 ? -63.736 19.588  43.137  1   26.11  ? 216 PHE C CD1 1 
ATOM   6296 C  CD2 . PHE C 1 220 ? -64.327 20.003  45.413  1   29.75  ? 216 PHE C CD2 1 
ATOM   6297 C  CE1 . PHE C 1 220 ? -63.63  18.233  43.406  1   26.6   ? 216 PHE C CE1 1 
ATOM   6298 C  CE2 . PHE C 1 220 ? -64.201 18.646  45.681  1   32.31  ? 216 PHE C CE2 1 
ATOM   6299 C  CZ  . PHE C 1 220 ? -63.858 17.759  44.674  1   28.88  ? 216 PHE C CZ  1 
ATOM   6300 N  N   . ARG C 1 221 ? -63.521 24.773  42.79   1   26.96  ? 217 ARG C N   1 
ATOM   6301 C  CA  . ARG C 1 221 ? -63.787 26.199  42.646  1   28.29  ? 217 ARG C CA  1 
ATOM   6302 C  C   . ARG C 1 221 ? -63.905 26.552  41.155  1   31.73  ? 217 ARG C C   1 
ATOM   6303 O  O   . ARG C 1 221 ? -64.707 27.408  40.769  1   33.49  ? 217 ARG C O   1 
ATOM   6304 C  CB  . ARG C 1 221 ? -62.752 27.019  43.438  1   27.15  ? 217 ARG C CB  1 
ATOM   6305 C  CG  . ARG C 1 221 ? -63.146 27.376  44.868  1   30.22  ? 217 ARG C CG  1 
ATOM   6306 C  CD  . ARG C 1 221 ? -62.049 27.569  45.928  1   29.97  ? 217 ARG C CD  1 
ATOM   6307 N  NE  . ARG C 1 221 ? -62.563 28.144  47.179  1   29.45  ? 217 ARG C NE  1 
ATOM   6308 C  CZ  . ARG C 1 221 ? -62.018 28.164  48.406  1   29.07  ? 217 ARG C CZ  1 
ATOM   6309 N  NH1 . ARG C 1 221 ? -62.544 28.984  49.312  1   25.87  ? 217 ARG C NH1 1 
ATOM   6310 N  NH2 . ARG C 1 221 ? -60.947 27.426  48.704  1   25.78  ? 217 ARG C NH2 1 
ATOM   6311 N  N   . THR C 1 222 ? -63.135 25.854  40.302  1   31.86  ? 218 THR C N   1 
ATOM   6312 C  CA  . THR C 1 222 ? -63.017 26.214  38.897  1   31.43  ? 218 THR C CA  1 
ATOM   6313 C  C   . THR C 1 222 ? -63.994 25.417  38.025  1   33.4   ? 218 THR C C   1 
ATOM   6314 O  O   . THR C 1 222 ? -64.662 26.008  37.163  1   33.87  ? 218 THR C O   1 
ATOM   6315 C  CB  . THR C 1 222 ? -61.564 26.052  38.45   1   30.25  ? 218 THR C CB  1 
ATOM   6316 O  OG1 . THR C 1 222 ? -60.871 27.137  39.06   1   26.78  ? 218 THR C OG1 1 
ATOM   6317 C  CG2 . THR C 1 222 ? -61.386 26.087  36.94   1   30.69  ? 218 THR C CG2 1 
ATOM   6318 N  N   . LEU C 1 223 ? -64.066 24.092  38.241  1   29.6   ? 219 LEU C N   1 
ATOM   6319 C  CA  . LEU C 1 223 ? -64.835 23.223  37.358  1   30.78  ? 219 LEU C CA  1 
ATOM   6320 C  C   . LEU C 1 223 ? -66.207 22.875  37.944  1   34.27  ? 219 LEU C C   1 
ATOM   6321 O  O   . LEU C 1 223 ? -66.963 22.146  37.309  1   37.4   ? 219 LEU C O   1 
ATOM   6322 C  CB  . LEU C 1 223 ? -64.026 21.955  37.082  1   31.22  ? 219 LEU C CB  1 
ATOM   6323 C  CG  . LEU C 1 223 ? -62.6   22.137  36.536  1   29.83  ? 219 LEU C CG  1 
ATOM   6324 C  CD1 . LEU C 1 223 ? -61.89  20.804  36.463  1   27.89  ? 219 LEU C CD1 1 
ATOM   6325 C  CD2 . LEU C 1 223 ? -62.546 22.816  35.166  1   28.92  ? 219 LEU C CD2 1 
ATOM   6326 N  N   . GLY C 1 224 ? -66.527 23.384  39.147  1   35.54  ? 220 GLY C N   1 
ATOM   6327 C  CA  . GLY C 1 224 ? -67.749 23.03   39.86   1   33.43  ? 220 GLY C CA  1 
ATOM   6328 C  C   . GLY C 1 224 ? -67.529 21.777  40.699  1   33.41  ? 220 GLY C C   1 
ATOM   6329 O  O   . GLY C 1 224 ? -66.725 20.936  40.333  1   32.81  ? 220 GLY C O   1 
ATOM   6330 N  N   . THR C 1 225 ? -68.193 21.68   41.854  1   37.01  ? 221 THR C N   1 
ATOM   6331 C  CA  . THR C 1 225 ? -68.076 20.47   42.652  1   39.97  ? 221 THR C CA  1 
ATOM   6332 C  C   . THR C 1 225 ? -68.767 19.36   41.872  1   41.67  ? 221 THR C C   1 
ATOM   6333 O  O   . THR C 1 225 ? -69.905 19.545  41.447  1   38.07  ? 221 THR C O   1 
ATOM   6334 C  CB  . THR C 1 225 ? -68.707 20.637  44.038  1   38.79  ? 221 THR C CB  1 
ATOM   6335 O  OG1 . THR C 1 225 ? -68.153 21.828  44.589  1   33.13  ? 221 THR C OG1 1 
ATOM   6336 C  CG2 . THR C 1 225 ? -68.432 19.447  44.943  1   37.07  ? 221 THR C CG2 1 
ATOM   6337 N  N   . PRO C 1 226 ? -68.115 18.191  41.658  1   48.63  ? 222 PRO C N   1 
ATOM   6338 C  CA  . PRO C 1 226 ? -68.768 17.093  40.948  1   52.26  ? 222 PRO C CA  1 
ATOM   6339 C  C   . PRO C 1 226 ? -69.885 16.551  41.837  1   56.99  ? 222 PRO C C   1 
ATOM   6340 O  O   . PRO C 1 226 ? -69.832 16.666  43.064  1   55.51  ? 222 PRO C O   1 
ATOM   6341 C  CB  . PRO C 1 226 ? -67.636 16.08   40.675  1   53.05  ? 222 PRO C CB  1 
ATOM   6342 C  CG  . PRO C 1 226 ? -66.573 16.391  41.72   1   47.71  ? 222 PRO C CG  1 
ATOM   6343 C  CD  . PRO C 1 226 ? -66.742 17.858  42.085  1   47.8   ? 222 PRO C CD  1 
ATOM   6344 N  N   . ASP C 1 227 ? -70.926 16.04   41.181  1   62.26  ? 223 ASP C N   1 
ATOM   6345 C  CA  . ASP C 1 227 ? -72.006 15.304  41.819  1   59.95  ? 223 ASP C CA  1 
ATOM   6346 C  C   . ASP C 1 227 ? -72.134 13.982  41.065  1   55.93  ? 223 ASP C C   1 
ATOM   6347 O  O   . ASP C 1 227 ? -71.329 13.698  40.178  1   51.2   ? 223 ASP C O   1 
ATOM   6348 C  CB  . ASP C 1 227 ? -73.272 16.149  41.857  1   58.87  ? 223 ASP C CB  1 
ATOM   6349 C  CG  . ASP C 1 227 ? -73.623 16.822  40.536  1   62.91  ? 223 ASP C CG  1 
ATOM   6350 O  OD1 . ASP C 1 227 ? -72.933 16.53   39.528  1   70.9   ? 223 ASP C OD1 1 
ATOM   6351 O  OD2 . ASP C 1 227 ? -74.571 17.636  40.518  1   60.99  ? 223 ASP C OD2 1 
ATOM   6352 N  N   . GLU C 1 228 ? -73.15  13.188  41.416  1   54.7   ? 224 GLU C N   1 
ATOM   6353 C  CA  . GLU C 1 228 ? -73.386 11.92   40.75   1   52.09  ? 224 GLU C CA  1 
ATOM   6354 C  C   . GLU C 1 228 ? -73.742 12.128  39.277  1   52.33  ? 224 GLU C C   1 
ATOM   6355 O  O   . GLU C 1 228 ? -73.375 11.289  38.462  1   56.18  ? 224 GLU C O   1 
ATOM   6356 C  CB  . GLU C 1 228 ? -74.411 11.098  41.529  1   51.54  ? 224 GLU C CB  1 
ATOM   6357 C  CG  . GLU C 1 228 ? -73.835 10.473  42.796  1   51.2   ? 224 GLU C CG  1 
ATOM   6358 C  CD  . GLU C 1 228 ? -72.735 9.439   42.595  1   50.73  ? 224 GLU C CD  1 
ATOM   6359 O  OE1 . GLU C 1 228 ? -72.936 8.493   41.801  1   47.91  ? 224 GLU C OE1 1 
ATOM   6360 O  OE2 . GLU C 1 228 ? -71.682 9.564   43.255  1   50.33  ? 224 GLU C OE2 1 
ATOM   6361 N  N   . VAL C 1 229 ? -74.414 13.241  38.935  1   50.57  ? 225 VAL C N   1 
ATOM   6362 C  CA  . VAL C 1 229 ? -74.864 13.518  37.571  1   47.79  ? 225 VAL C CA  1 
ATOM   6363 C  C   . VAL C 1 229 ? -73.68  13.818  36.633  1   48.49  ? 225 VAL C C   1 
ATOM   6364 O  O   . VAL C 1 229 ? -73.699 13.438  35.456  1   47.88  ? 225 VAL C O   1 
ATOM   6365 C  CB  . VAL C 1 229 ? -76.023 14.537  37.436  1   43.95  ? 225 VAL C CB  1 
ATOM   6366 C  CG1 . VAL C 1 229 ? -75.672 15.945  37.906  1   48.32  ? 225 VAL C CG1 1 
ATOM   6367 C  CG2 . VAL C 1 229 ? -76.523 14.632  36.01   1   41.23  ? 225 VAL C CG2 1 
ATOM   6368 N  N   . VAL C 1 230 ? -72.638 14.481  37.15   1   48.43  ? 226 VAL C N   1 
ATOM   6369 C  CA  . VAL C 1 230 ? -71.45  14.785  36.355  1   53.57  ? 226 VAL C CA  1 
ATOM   6370 C  C   . VAL C 1 230 ? -70.48  13.595  36.327  1   57.68  ? 226 VAL C C   1 
ATOM   6371 O  O   . VAL C 1 230 ? -69.866 13.306  35.294  1   61.44  ? 226 VAL C O   1 
ATOM   6372 C  CB  . VAL C 1 230 ? -70.745 16.078  36.817  1   53.41  ? 226 VAL C CB  1 
ATOM   6373 C  CG1 . VAL C 1 230 ? -69.395 16.273  36.13   1   50.87  ? 226 VAL C CG1 1 
ATOM   6374 C  CG2 . VAL C 1 230 ? -71.632 17.306  36.615  1   50.9   ? 226 VAL C CG2 1 
ATOM   6375 N  N   . TRP C 1 231 ? -70.346 12.914  37.473  1   55.37  ? 227 TRP C N   1 
ATOM   6376 C  CA  . TRP C 1 231 ? -69.34  11.885  37.679  1   46.27  ? 227 TRP C CA  1 
ATOM   6377 C  C   . TRP C 1 231 ? -69.922 10.775  38.546  1   48.87  ? 227 TRP C C   1 
ATOM   6378 O  O   . TRP C 1 231 ? -69.772 10.801  39.765  1   45.9   ? 227 TRP C O   1 
ATOM   6379 C  CB  . TRP C 1 231 ? -68.114 12.515  38.352  1   42.25  ? 227 TRP C CB  1 
ATOM   6380 C  CG  . TRP C 1 231 ? -66.942 11.59   38.543  1   40.47  ? 227 TRP C CG  1 
ATOM   6381 C  CD1 . TRP C 1 231 ? -66.821 10.303  38.106  1   39.51  ? 227 TRP C CD1 1 
ATOM   6382 C  CD2 . TRP C 1 231 ? -65.695 11.917  39.192  1   38.92  ? 227 TRP C CD2 1 
ATOM   6383 N  NE1 . TRP C 1 231 ? -65.599 9.8     38.455  1   39.33  ? 227 TRP C NE1 1 
ATOM   6384 C  CE2 . TRP C 1 231 ? -64.883 10.766  39.114  1   39.37  ? 227 TRP C CE2 1 
ATOM   6385 C  CE3 . TRP C 1 231 ? -65.185 13.062  39.817  1   39.09  ? 227 TRP C CE3 1 
ATOM   6386 C  CZ2 . TRP C 1 231 ? -63.594 10.733  39.643  1   37.75  ? 227 TRP C CZ2 1 
ATOM   6387 C  CZ3 . TRP C 1 231 ? -63.91  13.031  40.342  1   37.74  ? 227 TRP C CZ3 1 
ATOM   6388 C  CH2 . TRP C 1 231 ? -63.127 11.88   40.248  1   39.06  ? 227 TRP C CH2 1 
ATOM   6389 N  N   . PRO C 1 232 ? -70.596 9.76    37.955  1   56.64  ? 228 PRO C N   1 
ATOM   6390 C  CA  . PRO C 1 232 ? -71.175 8.67    38.745  1   55.86  ? 228 PRO C CA  1 
ATOM   6391 C  C   . PRO C 1 232 ? -70.087 8.004   39.587  1   55.48  ? 228 PRO C C   1 
ATOM   6392 O  O   . PRO C 1 232 ? -68.967 7.813   39.109  1   52.65  ? 228 PRO C O   1 
ATOM   6393 C  CB  . PRO C 1 232 ? -71.776 7.713   37.685  1   52.78  ? 228 PRO C CB  1 
ATOM   6394 C  CG  . PRO C 1 232 ? -71.946 8.572   36.443  1   50.2   ? 228 PRO C CG  1 
ATOM   6395 C  CD  . PRO C 1 232 ? -70.814 9.593   36.507  1   54.66  ? 228 PRO C CD  1 
ATOM   6396 N  N   . GLY C 1 233 ? -70.43  7.686   40.844  1   54.64  ? 229 GLY C N   1 
ATOM   6397 C  CA  . GLY C 1 233 ? -69.55  6.954   41.742  1   59.35  ? 229 GLY C CA  1 
ATOM   6398 C  C   . GLY C 1 233 ? -68.546 7.846   42.476  1   61.06  ? 229 GLY C C   1 
ATOM   6399 O  O   . GLY C 1 233 ? -67.728 7.327   43.24   1   67.35  ? 229 GLY C O   1 
ATOM   6400 N  N   . VAL C 1 234 ? -68.617 9.169   42.245  1   51.77  ? 230 VAL C N   1 
ATOM   6401 C  CA  . VAL C 1 234 ? -67.723 10.126  42.88   1   44.05  ? 230 VAL C CA  1 
ATOM   6402 C  C   . VAL C 1 234 ? -68.002 10.184  44.382  1   42.55  ? 230 VAL C C   1 
ATOM   6403 O  O   . VAL C 1 234 ? -67.059 10.236  45.171  1   43.12  ? 230 VAL C O   1 
ATOM   6404 C  CB  . VAL C 1 234 ? -67.746 11.537  42.262  1   41.37  ? 230 VAL C CB  1 
ATOM   6405 C  CG1 . VAL C 1 234 ? -69.089 12.233  42.435  1   40.54  ? 230 VAL C CG1 1 
ATOM   6406 C  CG2 . VAL C 1 234 ? -66.636 12.426  42.81   1   37.27  ? 230 VAL C CG2 1 
ATOM   6407 N  N   . THR C 1 235 ? -69.287 10.168  44.767  1   41.19  ? 231 THR C N   1 
ATOM   6408 C  CA  . THR C 1 235 ? -69.651 10.325  46.172  1   43.86  ? 231 THR C CA  1 
ATOM   6409 C  C   . THR C 1 235 ? -69.297 9.062   46.967  1   41.84  ? 231 THR C C   1 
ATOM   6410 O  O   . THR C 1 235 ? -69.347 9.075   48.2    1   41.05  ? 231 THR C O   1 
ATOM   6411 C  CB  . THR C 1 235 ? -71.111 10.756  46.378  1   46.01  ? 231 THR C CB  1 
ATOM   6412 O  OG1 . THR C 1 235 ? -71.968 9.677   46.02   1   46.76  ? 231 THR C OG1 1 
ATOM   6413 C  CG2 . THR C 1 235 ? -71.509 11.999  45.6    1   45.38  ? 231 THR C CG2 1 
ATOM   6414 N  N   . SER C 1 236 ? -68.983 7.999   46.235  1   41.7   ? 232 SER C N   1 
ATOM   6415 C  CA  . SER C 1 236 ? -68.635 6.715   46.884  1   43.01  ? 232 SER C CA  1 
ATOM   6416 C  C   . SER C 1 236 ? -67.113 6.578   46.872  1   46.6   ? 232 SER C C   1 
ATOM   6417 O  O   . SER C 1 236 ? -66.61  5.469   47.104  1   49.88  ? 232 SER C O   1 
ATOM   6418 C  CB  . SER C 1 236 ? -69.32  5.568   46.195  1   37.33  ? 232 SER C CB  1 
ATOM   6419 O  OG  . SER C 1 236 ? -70.659 5.9     45.86   1   33.03  ? 232 SER C OG  1 
ATOM   6420 N  N   . MET C 1 237 ? -66.424 7.683   46.614  1   47.17  ? 233 MET C N   1 
ATOM   6421 C  CA  . MET C 1 237 ? -64.946 7.664   46.576  1   48.12  ? 233 MET C CA  1 
ATOM   6422 C  C   . MET C 1 237 ? -64.392 7.666   48.003  1   47.04  ? 233 MET C C   1 
ATOM   6423 O  O   . MET C 1 237 ? -64.95  8.354   48.868  1   44.19  ? 233 MET C O   1 
ATOM   6424 C  CB  . MET C 1 237 ? -64.409 8.9     45.858  1   53.12  ? 233 MET C CB  1 
ATOM   6425 C  CG  . MET C 1 237 ? -64.804 9       44.417  1   60.55  ? 233 MET C CG  1 
ATOM   6426 S  SD  . MET C 1 237 ? -64.121 7.655   43.434  1   71.19  ? 233 MET C SD  1 
ATOM   6427 C  CE  . MET C 1 237 ? -64.777 8.083   41.818  1   64.92  ? 233 MET C CE  1 
ATOM   6428 N  N   . PRO C 1 238 ? -63.307 6.918   48.264  1   47.54  ? 234 PRO C N   1 
ATOM   6429 C  CA  . PRO C 1 238 ? -62.7   6.903   49.585  1   45.45  ? 234 PRO C CA  1 
ATOM   6430 C  C   . PRO C 1 238 ? -62.451 8.242   50.249  1   43.86  ? 234 PRO C C   1 
ATOM   6431 O  O   . PRO C 1 238 ? -62.876 8.444   51.396  1   37.71  ? 234 PRO C O   1 
ATOM   6432 C  CB  . PRO C 1 238 ? -61.371 6.257   49.187  1   46.51  ? 234 PRO C CB  1 
ATOM   6433 C  CG  . PRO C 1 238 ? -61.738 5.25    48.139  1   45.37  ? 234 PRO C CG  1 
ATOM   6434 C  CD  . PRO C 1 238 ? -62.667 6.061   47.281  1   46.31  ? 234 PRO C CD  1 
ATOM   6435 N  N   . ASP C 1 239 ? -61.764 9.142   49.552  1   44.83  ? 235 ASP C N   1 
ATOM   6436 C  CA  . ASP C 1 239 ? -61.366 10.41   50.144  1   47     ? 235 ASP C CA  1 
ATOM   6437 C  C   . ASP C 1 239 ? -62.379 11.509  49.821  1   49.35  ? 235 ASP C C   1 
ATOM   6438 O  O   . ASP C 1 239 ? -62.108 12.686  50.072  1   49.59  ? 235 ASP C O   1 
ATOM   6439 C  CB  . ASP C 1 239 ? -59.936 10.761  49.759  1   47.52  ? 235 ASP C CB  1 
ATOM   6440 C  CG  . ASP C 1 239 ? -58.868 9.819   50.302  1   53.33  ? 235 ASP C CG  1 
ATOM   6441 O  OD1 . ASP C 1 239 ? -59.126 9.207   51.364  1   59.66  ? 235 ASP C OD1 1 
ATOM   6442 O  OD2 . ASP C 1 239 ? -57.807 9.668   49.64   1   51.4   ? 235 ASP C OD2 1 
ATOM   6443 N  N   . TYR C 1 240 ? -63.545 11.117  49.28   1   47.04  ? 236 TYR C N   1 
ATOM   6444 C  CA  . TYR C 1 240 ? -64.63  12.046  48.989  1   43.19  ? 236 TYR C CA  1 
ATOM   6445 C  C   . TYR C 1 240 ? -65.359 12.385  50.291  1   45.16  ? 236 TYR C C   1 
ATOM   6446 O  O   . TYR C 1 240 ? -65.662 11.491  51.079  1   48.94  ? 236 TYR C O   1 
ATOM   6447 C  CB  . TYR C 1 240 ? -65.567 11.454  47.926  1   41.62  ? 236 TYR C CB  1 
ATOM   6448 C  CG  . TYR C 1 240 ? -66.794 12.316  47.649  1   43.41  ? 236 TYR C CG  1 
ATOM   6449 C  CD1 . TYR C 1 240 ? -67.928 12.26   48.47   1   44.66  ? 236 TYR C CD1 1 
ATOM   6450 C  CD2 . TYR C 1 240 ? -66.802 13.214  46.589  1   42.9   ? 236 TYR C CD2 1 
ATOM   6451 C  CE1 . TYR C 1 240 ? -69.039 13.059  48.235  1   43.63  ? 236 TYR C CE1 1 
ATOM   6452 C  CE2 . TYR C 1 240 ? -67.904 14.015  46.339  1   42.83  ? 236 TYR C CE2 1 
ATOM   6453 C  CZ  . TYR C 1 240 ? -69.019 13.938  47.159  1   45.16  ? 236 TYR C CZ  1 
ATOM   6454 O  OH  . TYR C 1 240 ? -70.065 14.767  46.874  1   46.64  ? 236 TYR C OH  1 
ATOM   6455 N  N   . LYS C 1 241 ? -65.666 13.676  50.496  1   47.54  ? 237 LYS C N   1 
ATOM   6456 C  CA  . LYS C 1 241 ? -66.347 14.149  51.699  1   45.49  ? 237 LYS C CA  1 
ATOM   6457 C  C   . LYS C 1 241 ? -67.737 14.687  51.335  1   41.41  ? 237 LYS C C   1 
ATOM   6458 O  O   . LYS C 1 241 ? -67.866 15.573  50.486  1   36.15  ? 237 LYS C O   1 
ATOM   6459 C  CB  . LYS C 1 241 ? -65.452 15.163  52.431  1   46.25  ? 237 LYS C CB  1 
ATOM   6460 C  CG  . LYS C 1 241 ? -64.17  14.611  53.085  1   46.53  ? 237 LYS C CG  1 
ATOM   6461 C  CD  . LYS C 1 241 ? -62.955 15.537  53.025  1   48.94  ? 237 LYS C CD  1 
ATOM   6462 C  CE  . LYS C 1 241 ? -63.121 16.93   53.592  1   52.14  ? 237 LYS C CE  1 
ATOM   6463 N  NZ  . LYS C 1 241 ? -63.361 17      55.037  1   49.42  ? 237 LYS C NZ  1 
ATOM   6464 N  N   . PRO C 1 242 ? -68.832 14.179  51.955  1   44.14  ? 238 PRO C N   1 
ATOM   6465 C  CA  . PRO C 1 242 ? -70.149 14.822  51.841  1   46.62  ? 238 PRO C CA  1 
ATOM   6466 C  C   . PRO C 1 242 ? -70.142 16.35   52.001  1   47.21  ? 238 PRO C C   1 
ATOM   6467 O  O   . PRO C 1 242 ? -70.914 17.05   51.344  1   46.66  ? 238 PRO C O   1 
ATOM   6468 C  CB  . PRO C 1 242 ? -71.023 14.138  52.935  1   41.19  ? 238 PRO C CB  1 
ATOM   6469 C  CG  . PRO C 1 242 ? -70.326 12.832  53.244  1   39.31  ? 238 PRO C CG  1 
ATOM   6470 C  CD  . PRO C 1 242 ? -68.866 12.979  52.812  1   42.19  ? 238 PRO C CD  1 
ATOM   6471 N  N   . SER C 1 243 ? -69.262 16.867  52.876  1   44.81  ? 239 SER C N   1 
ATOM   6472 C  CA  . SER C 1 243 ? -69.302 18.248  53.345  1   42.58  ? 239 SER C CA  1 
ATOM   6473 C  C   . SER C 1 243 ? -68.616 19.228  52.384  1   43.41  ? 239 SER C C   1 
ATOM   6474 O  O   . SER C 1 243 ? -68.584 20.425  52.668  1   46.5   ? 239 SER C O   1 
ATOM   6475 C  CB  . SER C 1 243 ? -68.761 18.36   54.748  1   38.33  ? 239 SER C CB  1 
ATOM   6476 O  OG  . SER C 1 243 ? -67.492 17.724  54.816  1   39.52  ? 239 SER C OG  1 
ATOM   6477 N  N   . PHE C 1 244 ? -68.09  18.748  51.244  1   41.37  ? 240 PHE C N   1 
ATOM   6478 C  CA  . PHE C 1 244 ? -67.492 19.614  50.226  1   38.89  ? 240 PHE C CA  1 
ATOM   6479 C  C   . PHE C 1 244 ? -68.419 20.784  49.859  1   37.65  ? 240 PHE C C   1 
ATOM   6480 O  O   . PHE C 1 244 ? -69.589 20.548  49.546  1   35.2   ? 240 PHE C O   1 
ATOM   6481 C  CB  . PHE C 1 244 ? -67.268 18.783  48.962  1   38.99  ? 240 PHE C CB  1 
ATOM   6482 C  CG  . PHE C 1 244 ? -66.038 17.892  48.96   1   44.75  ? 240 PHE C CG  1 
ATOM   6483 C  CD1 . PHE C 1 244 ? -64.985 18.112  49.849  1   48.04  ? 240 PHE C CD1 1 
ATOM   6484 C  CD2 . PHE C 1 244 ? -65.939 16.835  48.053  1   46.13  ? 240 PHE C CD2 1 
ATOM   6485 C  CE1 . PHE C 1 244 ? -63.853 17.299  49.817  1   53.88  ? 240 PHE C CE1 1 
ATOM   6486 C  CE2 . PHE C 1 244 ? -64.809 16.024  48.023  1   46.74  ? 240 PHE C CE2 1 
ATOM   6487 C  CZ  . PHE C 1 244 ? -63.765 16.26   48.898  1   48.69  ? 240 PHE C CZ  1 
ATOM   6488 N  N   . PRO C 1 245 ? -67.966 22.078  49.824  1   36.62  ? 241 PRO C N   1 
ATOM   6489 C  CA  . PRO C 1 245 ? -68.846 23.172  49.392  1   34.21  ? 241 PRO C CA  1 
ATOM   6490 C  C   . PRO C 1 245 ? -69.317 22.907  47.954  1   38.19  ? 241 PRO C C   1 
ATOM   6491 O  O   . PRO C 1 245 ? -68.709 22.108  47.24   1   36.79  ? 241 PRO C O   1 
ATOM   6492 C  CB  . PRO C 1 245 ? -67.995 24.444  49.542  1   26.76  ? 241 PRO C CB  1 
ATOM   6493 C  CG  . PRO C 1 245 ? -66.896 24.039  50.455  1   25.61  ? 241 PRO C CG  1 
ATOM   6494 C  CD  . PRO C 1 245 ? -66.608 22.582  50.107  1   29.91  ? 241 PRO C CD  1 
ATOM   6495 N  N   . LYS C 1 246 ? -70.441 23.523  47.559  1   42.74  ? 242 LYS C N   1 
ATOM   6496 C  CA  . LYS C 1 246 ? -71.062 23.304  46.258  1   45.44  ? 242 LYS C CA  1 
ATOM   6497 C  C   . LYS C 1 246 ? -70.829 24.527  45.357  1   42.25  ? 242 LYS C C   1 
ATOM   6498 O  O   . LYS C 1 246 ? -71.756 25.295  45.083  1   40.05  ? 242 LYS C O   1 
ATOM   6499 C  CB  . LYS C 1 246 ? -72.526 22.865  46.448  1   49.42  ? 242 LYS C CB  1 
ATOM   6500 C  CG  . LYS C 1 246 ? -73.283 22.377  45.213  1   57.89  ? 242 LYS C CG  1 
ATOM   6501 C  CD  . LYS C 1 246 ? -72.752 21.033  44.719  1   68.3   ? 242 LYS C CD  1 
ATOM   6502 C  CE  . LYS C 1 246 ? -73.128 20.574  43.339  1   65.14  ? 242 LYS C CE  1 
ATOM   6503 N  NZ  . LYS C 1 246 ? -72.325 19.384  43.019  1   64.08  ? 242 LYS C NZ  1 
ATOM   6504 N  N   . TRP C 1 247 ? -69.576 24.679  44.891  1   39.94  ? 243 TRP C N   1 
ATOM   6505 C  CA  . TRP C 1 247 ? -69.156 25.748  43.989  1   36.86  ? 243 TRP C CA  1 
ATOM   6506 C  C   . TRP C 1 247 ? -69.775 25.566  42.607  1   38.06  ? 243 TRP C C   1 
ATOM   6507 O  O   . TRP C 1 247 ? -69.944 24.44   42.133  1   36.92  ? 243 TRP C O   1 
ATOM   6508 C  CB  . TRP C 1 247 ? -67.626 25.84   43.866  1   33.51  ? 243 TRP C CB  1 
ATOM   6509 C  CG  . TRP C 1 247 ? -66.93  26.342  45.106  1   30.48  ? 243 TRP C CG  1 
ATOM   6510 C  CD1 . TRP C 1 247 ? -66.924 27.629  45.55   1   27.1   ? 243 TRP C CD1 1 
ATOM   6511 C  CD2 . TRP C 1 247 ? -66.119 25.579  46.035  1   28.47  ? 243 TRP C CD2 1 
ATOM   6512 N  NE1 . TRP C 1 247 ? -66.195 27.709  46.702  1   27.8   ? 243 TRP C NE1 1 
ATOM   6513 C  CE2 . TRP C 1 247 ? -65.679 26.48   47.025  1   28.8   ? 243 TRP C CE2 1 
ATOM   6514 C  CE3 . TRP C 1 247 ? -65.715 24.242  46.137  1   26.55  ? 243 TRP C CE3 1 
ATOM   6515 C  CZ2 . TRP C 1 247 ? -64.862 26.083  48.092  1   28.5   ? 243 TRP C CZ2 1 
ATOM   6516 C  CZ3 . TRP C 1 247 ? -64.915 23.852  47.194  1   28.25  ? 243 TRP C CZ3 1 
ATOM   6517 C  CH2 . TRP C 1 247 ? -64.49  24.759  48.167  1   28.01  ? 243 TRP C CH2 1 
ATOM   6518 N  N   . ALA C 1 248 ? -70.087 26.704  41.974  1   38.33  ? 244 ALA C N   1 
ATOM   6519 C  CA  . ALA C 1 248 ? -70.552 26.748  40.598  1   39.52  ? 244 ALA C CA  1 
ATOM   6520 C  C   . ALA C 1 248 ? -69.343 26.778  39.653  1   42.37  ? 244 ALA C C   1 
ATOM   6521 O  O   . ALA C 1 248 ? -68.328 27.414  39.958  1   47.23  ? 244 ALA C O   1 
ATOM   6522 C  CB  . ALA C 1 248 ? -71.461 27.947  40.43   1   35.18  ? 244 ALA C CB  1 
ATOM   6523 N  N   . ARG C 1 249 ? -69.436 26.049  38.529  1   40.77  ? 245 ARG C N   1 
ATOM   6524 C  CA  . ARG C 1 249 ? -68.388 26.047  37.518  1   44.01  ? 245 ARG C CA  1 
ATOM   6525 C  C   . ARG C 1 249 ? -68.237 27.464  36.978  1   48.25  ? 245 ARG C C   1 
ATOM   6526 O  O   . ARG C 1 249 ? -69.244 28.147  36.798  1   52.24  ? 245 ARG C O   1 
ATOM   6527 C  CB  . ARG C 1 249 ? -68.752 25.106  36.362  1   42.77  ? 245 ARG C CB  1 
ATOM   6528 C  CG  . ARG C 1 249 ? -67.664 24.932  35.31   1   44.07  ? 245 ARG C CG  1 
ATOM   6529 C  CD  . ARG C 1 249 ? -68.196 24.37   34.006  1   43.97  ? 245 ARG C CD  1 
ATOM   6530 N  NE  . ARG C 1 249 ? -67.175 23.856  33.083  1   41.95  ? 245 ARG C NE  1 
ATOM   6531 C  CZ  . ARG C 1 249 ? -66.525 22.696  33.18   1   37.76  ? 245 ARG C CZ  1 
ATOM   6532 N  NH1 . ARG C 1 249 ? -66.514 21.995  34.303  1   35.77  ? 245 ARG C NH1 1 
ATOM   6533 N  NH2 . ARG C 1 249 ? -65.847 22.256  32.144  1   36.09  ? 245 ARG C NH2 1 
ATOM   6534 N  N   . GLN C 1 250 ? -66.992 27.907  36.746  1   48.55  ? 246 GLN C N   1 
ATOM   6535 C  CA  . GLN C 1 250 ? -66.767 29.155  36.032  1   50.91  ? 246 GLN C CA  1 
ATOM   6536 C  C   . GLN C 1 250 ? -66.727 28.849  34.537  1   54.82  ? 246 GLN C C   1 
ATOM   6537 O  O   . GLN C 1 250 ? -66.292 27.766  34.136  1   58.57  ? 246 GLN C O   1 
ATOM   6538 C  CB  . GLN C 1 250 ? -65.454 29.807  36.458  1   55.45  ? 246 GLN C CB  1 
ATOM   6539 C  CG  . GLN C 1 250 ? -65.207 29.806  37.963  1   59.59  ? 246 GLN C CG  1 
ATOM   6540 C  CD  . GLN C 1 250 ? -63.879 30.436  38.318  1   66.11  ? 246 GLN C CD  1 
ATOM   6541 O  OE1 . GLN C 1 250 ? -63.365 31.307  37.607  1   72.75  ? 246 GLN C OE1 1 
ATOM   6542 N  NE2 . GLN C 1 250 ? -63.307 30.007  39.431  1   68.69  ? 246 GLN C NE2 1 
ATOM   6543 N  N   . ASP C 1 251 ? -67.209 29.785  33.709  1   58.12  ? 247 ASP C N   1 
ATOM   6544 C  CA  . ASP C 1 251 ? -67.108 29.572  32.274  1   61.05  ? 247 ASP C CA  1 
ATOM   6545 C  C   . ASP C 1 251 ? -65.652 29.795  31.887  1   55.55  ? 247 ASP C C   1 
ATOM   6546 O  O   . ASP C 1 251 ? -64.945 30.591  32.508  1   49.48  ? 247 ASP C O   1 
ATOM   6547 C  CB  . ASP C 1 251 ? -68.218 30.231  31.46   1   63.11  ? 247 ASP C CB  1 
ATOM   6548 C  CG  . ASP C 1 251 ? -68.215 31.753  31.392  1   70.97  ? 247 ASP C CG  1 
ATOM   6549 O  OD1 . ASP C 1 251 ? -67.191 32.372  31.776  1   84.21  ? 247 ASP C OD1 1 
ATOM   6550 O  OD2 . ASP C 1 251 ? -69.251 32.317  30.972  1   68.26  ? 247 ASP C OD2 1 
ATOM   6551 N  N   . PHE C 1 252 ? -65.216 29.011  30.902  1   53.24  ? 248 PHE C N   1 
ATOM   6552 C  CA  . PHE C 1 252 ? -63.815 28.918  30.542  1   53.52  ? 248 PHE C CA  1 
ATOM   6553 C  C   . PHE C 1 252 ? -63.326 30.256  29.999  1   54.7   ? 248 PHE C C   1 
ATOM   6554 O  O   . PHE C 1 252 ? -62.127 30.498  29.971  1   59.5   ? 248 PHE C O   1 
ATOM   6555 C  CB  . PHE C 1 252 ? -63.632 27.707  29.625  1   49.51  ? 248 PHE C CB  1 
ATOM   6556 C  CG  . PHE C 1 252 ? -63.392 26.414  30.389  1   49.05  ? 248 PHE C CG  1 
ATOM   6557 C  CD1 . PHE C 1 252 ? -63.893 26.227  31.676  1   50.92  ? 248 PHE C CD1 1 
ATOM   6558 C  CD2 . PHE C 1 252 ? -62.633 25.403  29.823  1   45.68  ? 248 PHE C CD2 1 
ATOM   6559 C  CE1 . PHE C 1 252 ? -63.643 25.054  32.372  1   51.05  ? 248 PHE C CE1 1 
ATOM   6560 C  CE2 . PHE C 1 252 ? -62.382 24.242  30.525  1   44.74  ? 248 PHE C CE2 1 
ATOM   6561 C  CZ  . PHE C 1 252 ? -62.888 24.067  31.792  1   46.99  ? 248 PHE C CZ  1 
ATOM   6562 N  N   . SER C 1 253 ? -64.269 31.116  29.592  1   53.64  ? 249 SER C N   1 
ATOM   6563 C  CA  . SER C 1 253 ? -63.977 32.489  29.208  1   57.84  ? 249 SER C CA  1 
ATOM   6564 C  C   . SER C 1 253 ? -63.301 33.267  30.347  1   62.15  ? 249 SER C C   1 
ATOM   6565 O  O   . SER C 1 253 ? -62.684 34.31   30.106  1   61.69  ? 249 SER C O   1 
ATOM   6566 C  CB  . SER C 1 253 ? -65.224 33.187  28.709  1   55.25  ? 249 SER C CB  1 
ATOM   6567 O  OG  . SER C 1 253 ? -65.161 34.584  28.977  1   53.26  ? 249 SER C OG  1 
ATOM   6568 N  N   . LYS C 1 254 ? -63.442 32.775  31.587  1   61.43  ? 250 LYS C N   1 
ATOM   6569 C  CA  . LYS C 1 254 ? -62.81  33.39   32.746  1   58.45  ? 250 LYS C CA  1 
ATOM   6570 C  C   . LYS C 1 254 ? -61.577 32.594  33.153  1   53.58  ? 250 LYS C C   1 
ATOM   6571 O  O   . LYS C 1 254 ? -60.588 33.191  33.574  1   54.68  ? 250 LYS C O   1 
ATOM   6572 C  CB  . LYS C 1 254 ? -63.811 33.656  33.878  1   63.46  ? 250 LYS C CB  1 
ATOM   6573 C  CG  . LYS C 1 254 ? -64.881 34.714  33.591  1   71.11  ? 250 LYS C CG  1 
ATOM   6574 C  CD  . LYS C 1 254 ? -65.919 35.001  34.678  1   80.39  ? 250 LYS C CD  1 
ATOM   6575 C  CE  . LYS C 1 254 ? -66.948 36.061  34.385  1   79.28  ? 250 LYS C CE  1 
ATOM   6576 N  NZ  . LYS C 1 254 ? -67.892 36.222  35.491  1   75.6   ? 250 LYS C NZ  1 
ATOM   6577 N  N   . VAL C 1 255 ? -61.65  31.262  33.007  1   48.11  ? 251 VAL C N   1 
ATOM   6578 C  CA  . VAL C 1 255 ? -60.526 30.383  33.301  1   46.87  ? 251 VAL C CA  1 
ATOM   6579 C  C   . VAL C 1 255 ? -59.376 30.703  32.347  1   41.46  ? 251 VAL C C   1 
ATOM   6580 O  O   . VAL C 1 255 ? -58.234 30.848  32.763  1   36.25  ? 251 VAL C O   1 
ATOM   6581 C  CB  . VAL C 1 255 ? -60.937 28.901  33.196  1   50.72  ? 251 VAL C CB  1 
ATOM   6582 C  CG1 . VAL C 1 255 ? -59.796 27.958  33.546  1   43.82  ? 251 VAL C CG1 1 
ATOM   6583 C  CG2 . VAL C 1 255 ? -62.166 28.605  34.051  1   56.93  ? 251 VAL C CG2 1 
ATOM   6584 N  N   . VAL C 1 256 ? -59.705 30.82   31.06   1   42.81  ? 252 VAL C N   1 
ATOM   6585 C  CA  . VAL C 1 256 ? -58.71  30.967  30.013  1   46.7   ? 252 VAL C CA  1 
ATOM   6586 C  C   . VAL C 1 256 ? -59.19  32.026  29.013  1   48.55  ? 252 VAL C C   1 
ATOM   6587 O  O   . VAL C 1 256 ? -59.599 31.703  27.892  1   45.76  ? 252 VAL C O   1 
ATOM   6588 C  CB  . VAL C 1 256 ? -58.449 29.599  29.349  1   43.45  ? 252 VAL C CB  1 
ATOM   6589 C  CG1 . VAL C 1 256 ? -57.213 29.654  28.481  1   46.85  ? 252 VAL C CG1 1 
ATOM   6590 C  CG2 . VAL C 1 256 ? -58.236 28.497  30.368  1   41.74  ? 252 VAL C CG2 1 
ATOM   6591 N  N   . PRO C 1 257 ? -59.184 33.329  29.4    1   52.36  ? 253 PRO C N   1 
ATOM   6592 C  CA  . PRO C 1 257 ? -59.645 34.408  28.516  1   49.23  ? 253 PRO C CA  1 
ATOM   6593 C  C   . PRO C 1 257 ? -59.036 34.398  27.113  1   51.81  ? 253 PRO C C   1 
ATOM   6594 O  O   . PRO C 1 257 ? -59.761 34.616  26.143  1   53.07  ? 253 PRO C O   1 
ATOM   6595 C  CB  . PRO C 1 257 ? -59.33  35.698  29.288  1   45.99  ? 253 PRO C CB  1 
ATOM   6596 C  CG  . PRO C 1 257 ? -59.332 35.253  30.733  1   47.68  ? 253 PRO C CG  1 
ATOM   6597 C  CD  . PRO C 1 257 ? -58.762 33.835  30.718  1   50.5   ? 253 PRO C CD  1 
ATOM   6598 N  N   . PRO C 1 258 ? -57.711 34.14   26.934  1   49.34  ? 254 PRO C N   1 
ATOM   6599 C  CA  . PRO C 1 258 ? -57.111 34.137  25.596  1   42.8   ? 254 PRO C CA  1 
ATOM   6600 C  C   . PRO C 1 258 ? -57.74  33.142  24.626  1   39     ? 254 PRO C C   1 
ATOM   6601 O  O   . PRO C 1 258 ? -57.772 33.394  23.428  1   40.47  ? 254 PRO C O   1 
ATOM   6602 C  CB  . PRO C 1 258 ? -55.618 33.834  25.829  1   41.17  ? 254 PRO C CB  1 
ATOM   6603 C  CG  . PRO C 1 258 ? -55.4   34.178  27.282  1   42.92  ? 254 PRO C CG  1 
ATOM   6604 C  CD  . PRO C 1 258 ? -56.712 33.885  27.988  1   45.1   ? 254 PRO C CD  1 
ATOM   6605 N  N   . LEU C 1 259 ? -58.245 32.025  25.159  1   37.2   ? 255 LEU C N   1 
ATOM   6606 C  CA  . LEU C 1 259 ? -58.48  30.834  24.356  1   36.58  ? 255 LEU C CA  1 
ATOM   6607 C  C   . LEU C 1 259 ? -59.773 30.969  23.559  1   38.33  ? 255 LEU C C   1 
ATOM   6608 O  O   . LEU C 1 259 ? -60.763 31.468  24.099  1   38.58  ? 255 LEU C O   1 
ATOM   6609 C  CB  . LEU C 1 259 ? -58.533 29.637  25.301  1   35.71  ? 255 LEU C CB  1 
ATOM   6610 C  CG  . LEU C 1 259 ? -58.049 28.297  24.737  1   35.23  ? 255 LEU C CG  1 
ATOM   6611 C  CD1 . LEU C 1 259 ? -56.646 28.383  24.123  1   33.47  ? 255 LEU C CD1 1 
ATOM   6612 C  CD2 . LEU C 1 259 ? -58.121 27.207  25.811  1   30.44  ? 255 LEU C CD2 1 
ATOM   6613 N  N   . ASP C 1 260 ? -59.735 30.522  22.288  1   38.94  ? 256 ASP C N   1 
ATOM   6614 C  CA  . ASP C 1 260 ? -60.875 30.543  21.369  1   40.47  ? 256 ASP C CA  1 
ATOM   6615 C  C   . ASP C 1 260 ? -61.908 29.505  21.818  1   39.64  ? 256 ASP C C   1 
ATOM   6616 O  O   . ASP C 1 260 ? -61.691 28.802  22.809  1   41.71  ? 256 ASP C O   1 
ATOM   6617 C  CB  . ASP C 1 260 ? -60.446 30.358  19.915  1   40.82  ? 256 ASP C CB  1 
ATOM   6618 C  CG  . ASP C 1 260 ? -59.593 29.12   19.625  1   43.36  ? 256 ASP C CG  1 
ATOM   6619 O  OD1 . ASP C 1 260 ? -58.5   28.997  20.227  1   40.99  ? 256 ASP C OD1 1 
ATOM   6620 O  OD2 . ASP C 1 260 ? -60.02  28.277  18.803  1   43.63  ? 256 ASP C OD2 1 
ATOM   6621 N  N   . GLU C 1 261 ? -63.011 29.388  21.063  1   36.47  ? 257 GLU C N   1 
ATOM   6622 C  CA  . GLU C 1 261 ? -64.103 28.469  21.366  1   37.19  ? 257 GLU C CA  1 
ATOM   6623 C  C   . GLU C 1 261 ? -63.66  27.001  21.299  1   37.5   ? 257 GLU C C   1 
ATOM   6624 O  O   . GLU C 1 261 ? -64.078 26.193  22.129  1   33.63  ? 257 GLU C O   1 
ATOM   6625 C  CB  . GLU C 1 261 ? -65.253 28.784  20.41   1   37.76  ? 257 GLU C CB  1 
ATOM   6626 C  CG  . GLU C 1 261 ? -66.479 27.888  20.547  1   42.01  ? 257 GLU C CG  1 
ATOM   6627 C  CD  . GLU C 1 261 ? -67.384 28.106  19.338  1   53.26  ? 257 GLU C CD  1 
ATOM   6628 O  OE1 . GLU C 1 261 ? -68.237 27.238  19.058  1   58.41  ? 257 GLU C OE1 1 
ATOM   6629 O  OE2 . GLU C 1 261 ? -67.239 29.153  18.662  1   54.27  ? 257 GLU C OE2 1 
ATOM   6630 N  N   . ASP C 1 262 ? -62.842 26.662  20.289  1   37.96  ? 258 ASP C N   1 
ATOM   6631 C  CA  . ASP C 1 262 ? -62.356 25.31   20.052  1   38.6   ? 258 ASP C CA  1 
ATOM   6632 C  C   . ASP C 1 262 ? -61.337 24.885  21.108  1   39.22  ? 258 ASP C C   1 
ATOM   6633 O  O   . ASP C 1 262 ? -61.305 23.721  21.517  1   38.57  ? 258 ASP C O   1 
ATOM   6634 C  CB  . ASP C 1 262 ? -61.713 25.178  18.683  1   40.56  ? 258 ASP C CB  1 
ATOM   6635 C  CG  . ASP C 1 262 ? -62.683 25.146  17.516  1   40.48  ? 258 ASP C CG  1 
ATOM   6636 O  OD1 . ASP C 1 262 ? -63.581 24.276  17.524  1   36.91  ? 258 ASP C OD1 1 
ATOM   6637 O  OD2 . ASP C 1 262 ? -62.519 25.986  16.613  1   42.49  ? 258 ASP C OD2 1 
ATOM   6638 N  N   . GLY C 1 263 ? -60.469 25.822  21.506  1   36.57  ? 259 GLY C N   1 
ATOM   6639 C  CA  . GLY C 1 263 ? -59.526 25.566  22.578  1   31.04  ? 259 GLY C CA  1 
ATOM   6640 C  C   . GLY C 1 263 ? -60.244 25.194  23.87   1   29.82  ? 259 GLY C C   1 
ATOM   6641 O  O   . GLY C 1 263 ? -59.852 24.25   24.545  1   32.55  ? 259 GLY C O   1 
ATOM   6642 N  N   . ARG C 1 264 ? -61.317 25.919  24.189  1   30.47  ? 260 ARG C N   1 
ATOM   6643 C  CA  . ARG C 1 264 ? -62.022 25.776  25.459  1   31.88  ? 260 ARG C CA  1 
ATOM   6644 C  C   . ARG C 1 264 ? -62.798 24.456  25.51   1   29.8   ? 260 ARG C C   1 
ATOM   6645 O  O   . ARG C 1 264 ? -62.843 23.793  26.541  1   31.1   ? 260 ARG C O   1 
ATOM   6646 C  CB  . ARG C 1 264 ? -62.916 27      25.702  1   34.22  ? 260 ARG C CB  1 
ATOM   6647 C  CG  . ARG C 1 264 ? -62.167 28.317  25.892  1   35.83  ? 260 ARG C CG  1 
ATOM   6648 C  CD  . ARG C 1 264 ? -63.043 29.479  26.361  1   34.68  ? 260 ARG C CD  1 
ATOM   6649 N  NE  . ARG C 1 264 ? -64.297 29.476  25.596  1   39.01  ? 260 ARG C NE  1 
ATOM   6650 C  CZ  . ARG C 1 264 ? -64.613 30.33   24.618  1   44.34  ? 260 ARG C CZ  1 
ATOM   6651 N  NH1 . ARG C 1 264 ? -63.775 31.305  24.294  1   47.67  ? 260 ARG C NH1 1 
ATOM   6652 N  NH2 . ARG C 1 264 ? -65.76  30.21   23.958  1   40.67  ? 260 ARG C NH2 1 
ATOM   6653 N  N   . SER C 1 265 ? -63.409 24.08   24.388  1   28.03  ? 261 SER C N   1 
ATOM   6654 C  CA  . SER C 1 265 ? -64.019 22.774  24.203  1   28.37  ? 261 SER C CA  1 
ATOM   6655 C  C   . SER C 1 265 ? -63.026 21.642  24.482  1   27.89  ? 261 SER C C   1 
ATOM   6656 O  O   . SER C 1 265 ? -63.308 20.714  25.242  1   26.6   ? 261 SER C O   1 
ATOM   6657 C  CB  . SER C 1 265 ? -64.57  22.674  22.807  1   29.95  ? 261 SER C CB  1 
ATOM   6658 O  OG  . SER C 1 265 ? -64.749 21.315  22.442  1   33.07  ? 261 SER C OG  1 
ATOM   6659 N  N   . LEU C 1 266 ? -61.859 21.707  23.84   1   27.62  ? 262 LEU C N   1 
ATOM   6660 C  CA  . LEU C 1 266 ? -60.857 20.674  24.039  1   29.08  ? 262 LEU C CA  1 
ATOM   6661 C  C   . LEU C 1 266 ? -60.419 20.623  25.51   1   30.9   ? 262 LEU C C   1 
ATOM   6662 O  O   . LEU C 1 266 ? -60.371 19.538  26.116  1   31.22  ? 262 LEU C O   1 
ATOM   6663 C  CB  . LEU C 1 266 ? -59.691 20.909  23.08   1   26.71  ? 262 LEU C CB  1 
ATOM   6664 C  CG  . LEU C 1 266 ? -58.476 20.005  23.311  1   26.6   ? 262 LEU C CG  1 
ATOM   6665 C  CD1 . LEU C 1 266 ? -58.834 18.554  23.045  1   23.26  ? 262 LEU C CD1 1 
ATOM   6666 C  CD2 . LEU C 1 266 ? -57.28  20.469  22.484  1   25.61  ? 262 LEU C CD2 1 
ATOM   6667 N  N   . LEU C 1 267 ? -60.104 21.802  26.076  1   28.49  ? 263 LEU C N   1 
ATOM   6668 C  CA  . LEU C 1 267 ? -59.685 21.921  27.468  1   26.75  ? 263 LEU C CA  1 
ATOM   6669 C  C   . LEU C 1 267 ? -60.667 21.198  28.395  1   26.58  ? 263 LEU C C   1 
ATOM   6670 O  O   . LEU C 1 267 ? -60.271 20.329  29.179  1   28.24  ? 263 LEU C O   1 
ATOM   6671 C  CB  . LEU C 1 267 ? -59.482 23.381  27.87   1   23.79  ? 263 LEU C CB  1 
ATOM   6672 C  CG  . LEU C 1 267 ? -58.958 23.612  29.29   1   22.86  ? 263 LEU C CG  1 
ATOM   6673 C  CD1 . LEU C 1 267 ? -57.644 22.894  29.515  1   24.28  ? 263 LEU C CD1 1 
ATOM   6674 C  CD2 . LEU C 1 267 ? -58.771 25.077  29.577  1   21.22  ? 263 LEU C CD2 1 
ATOM   6675 N  N   . SER C 1 268 ? -61.959 21.525  28.272  1   24.79  ? 264 SER C N   1 
ATOM   6676 C  CA  . SER C 1 268 ? -62.936 20.952  29.187  1   27.26  ? 264 SER C CA  1 
ATOM   6677 C  C   . SER C 1 268 ? -62.999 19.431  29.044  1   28.75  ? 264 SER C C   1 
ATOM   6678 O  O   . SER C 1 268 ? -63.119 18.726  30.045  1   34.61  ? 264 SER C O   1 
ATOM   6679 C  CB  . SER C 1 268 ? -64.278 21.59   29.041  1   25.63  ? 264 SER C CB  1 
ATOM   6680 O  OG  . SER C 1 268 ? -64.622 21.607  27.67   1   31.1   ? 264 SER C OG  1 
ATOM   6681 N  N   . GLN C 1 269 ? -62.872 18.93   27.808  1   25.48  ? 265 GLN C N   1 
ATOM   6682 C  CA  . GLN C 1 269 ? -62.858 17.496  27.573  1   24.93  ? 265 GLN C CA  1 
ATOM   6683 C  C   . GLN C 1 269 ? -61.622 16.855  28.193  1   25.49  ? 265 GLN C C   1 
ATOM   6684 O  O   . GLN C 1 269 ? -61.665 15.708  28.644  1   25.46  ? 265 GLN C O   1 
ATOM   6685 C  CB  . GLN C 1 269 ? -62.942 17.194  26.08   1   25.46  ? 265 GLN C CB  1 
ATOM   6686 C  CG  . GLN C 1 269 ? -64.331 17.429  25.501  1   25.82  ? 265 GLN C CG  1 
ATOM   6687 C  CD  . GLN C 1 269 ? -64.365 17.297  23.996  1   27.9   ? 265 GLN C CD  1 
ATOM   6688 O  OE1 . GLN C 1 269 ? -64.496 18.299  23.283  1   30.92  ? 265 GLN C OE1 1 
ATOM   6689 N  NE2 . GLN C 1 269 ? -64.216 16.074  23.496  1   26.3   ? 265 GLN C NE2 1 
ATOM   6690 N  N   . MET C 1 270 ? -60.514 17.601  28.201  1   26.72  ? 266 MET C N   1 
ATOM   6691 C  CA  . MET C 1 270 ? -59.311 17.11   28.853  1   26.24  ? 266 MET C CA  1 
ATOM   6692 C  C   . MET C 1 270 ? -59.458 17.184  30.367  1   25.18  ? 266 MET C C   1 
ATOM   6693 O  O   . MET C 1 270 ? -58.823 16.418  31.079  1   23.49  ? 266 MET C O   1 
ATOM   6694 C  CB  . MET C 1 270 ? -58.075 17.892  28.408  1   26.87  ? 266 MET C CB  1 
ATOM   6695 C  CG  . MET C 1 270 ? -57.629 17.505  27.01   1   26.44  ? 266 MET C CG  1 
ATOM   6696 S  SD  . MET C 1 270 ? -56.3   18.549  26.384  1   26.21  ? 266 MET C SD  1 
ATOM   6697 C  CE  . MET C 1 270 ? -54.888 17.784  27.202  1   21.86  ? 266 MET C CE  1 
ATOM   6698 N  N   . LEU C 1 271 ? -60.305 18.098  30.849  1   25.89  ? 267 LEU C N   1 
ATOM   6699 C  CA  . LEU C 1 271 ? -60.409 18.313  32.279  1   27.59  ? 267 LEU C CA  1 
ATOM   6700 C  C   . LEU C 1 271 ? -61.722 17.768  32.838  1   29.12  ? 267 LEU C C   1 
ATOM   6701 O  O   . LEU C 1 271 ? -62.135 18.18   33.917  1   31.54  ? 267 LEU C O   1 
ATOM   6702 C  CB  . LEU C 1 271 ? -60.244 19.804  32.566  1   27.29  ? 267 LEU C CB  1 
ATOM   6703 C  CG  . LEU C 1 271 ? -58.844 20.382  32.356  1   25.48  ? 267 LEU C CG  1 
ATOM   6704 C  CD1 . LEU C 1 271 ? -58.857 21.83   32.81   1   25.97  ? 267 LEU C CD1 1 
ATOM   6705 C  CD2 . LEU C 1 271 ? -57.8   19.564  33.093  1   24.11  ? 267 LEU C CD2 1 
ATOM   6706 N  N   . HIS C 1 272 ? -62.358 16.829  32.13   1   30.36  ? 268 HIS C N   1 
ATOM   6707 C  CA  . HIS C 1 272 ? -63.576 16.186  32.608  1   32.37  ? 268 HIS C CA  1 
ATOM   6708 C  C   . HIS C 1 272 ? -63.289 15.426  33.913  1   32.87  ? 268 HIS C C   1 
ATOM   6709 O  O   . HIS C 1 272 ? -62.252 14.767  34.06   1   30.52  ? 268 HIS C O   1 
ATOM   6710 C  CB  . HIS C 1 272 ? -64.149 15.305  31.491  1   37.7   ? 268 HIS C CB  1 
ATOM   6711 C  CG  . HIS C 1 272 ? -65.626 15.026  31.528  1   46.77  ? 268 HIS C CG  1 
ATOM   6712 N  ND1 . HIS C 1 272 ? -66.268 14.286  32.507  1   47.55  ? 268 HIS C ND1 1 
ATOM   6713 C  CD2 . HIS C 1 272 ? -66.588 15.413  30.669  1   46.33  ? 268 HIS C CD2 1 
ATOM   6714 C  CE1 . HIS C 1 272 ? -67.567 14.236  32.252  1   48.32  ? 268 HIS C CE1 1 
ATOM   6715 N  NE2 . HIS C 1 272 ? -67.782 14.907  31.137  1   52.52  ? 268 HIS C NE2 1 
ATOM   6716 N  N   . TYR C 1 273 ? -64.221 15.528  34.871  1   31.85  ? 269 TYR C N   1 
ATOM   6717 C  CA  . TYR C 1 273 ? -64.066 14.839  36.142  1   31.66  ? 269 TYR C CA  1 
ATOM   6718 C  C   . TYR C 1 273 ? -63.96  13.33   35.942  1   33.05  ? 269 TYR C C   1 
ATOM   6719 O  O   . TYR C 1 273 ? -63     12.71   36.405  1   32.69  ? 269 TYR C O   1 
ATOM   6720 C  CB  . TYR C 1 273 ? -65.24  15.142  37.067  1   30.51  ? 269 TYR C CB  1 
ATOM   6721 C  CG  . TYR C 1 273 ? -65.042 16.435  37.828  1   31.39  ? 269 TYR C CG  1 
ATOM   6722 C  CD1 . TYR C 1 273 ? -64.067 16.535  38.81   1   29.84  ? 269 TYR C CD1 1 
ATOM   6723 C  CD2 . TYR C 1 273 ? -65.832 17.545  37.563  1   33.02  ? 269 TYR C CD2 1 
ATOM   6724 C  CE1 . TYR C 1 273 ? -63.884 17.713  39.515  1   29.97  ? 269 TYR C CE1 1 
ATOM   6725 C  CE2 . TYR C 1 273 ? -65.647 18.733  38.257  1   32.65  ? 269 TYR C CE2 1 
ATOM   6726 C  CZ  . TYR C 1 273 ? -64.668 18.819  39.231  1   30.99  ? 269 TYR C CZ  1 
ATOM   6727 O  OH  . TYR C 1 273 ? -64.493 19.992  39.908  1   32.68  ? 269 TYR C OH  1 
ATOM   6728 N  N   . ASP C 1 274 ? -64.972 12.756  35.274  1   32.11  ? 270 ASP C N   1 
ATOM   6729 C  CA  . ASP C 1 274 ? -65.12  11.316  35.136  1   29.59  ? 270 ASP C CA  1 
ATOM   6730 C  C   . ASP C 1 274 ? -64.022 10.817  34.2    1   30.25  ? 270 ASP C C   1 
ATOM   6731 O  O   . ASP C 1 274 ? -63.963 11.228  33.042  1   29.57  ? 270 ASP C O   1 
ATOM   6732 C  CB  . ASP C 1 274 ? -66.53  10.955  34.688  1   28.24  ? 270 ASP C CB  1 
ATOM   6733 C  CG  . ASP C 1 274 ? -66.827 9.478   34.464  1   29.04  ? 270 ASP C CG  1 
ATOM   6734 O  OD1 . ASP C 1 274 ? -65.867 8.669   34.379  1   25.71  ? 270 ASP C OD1 1 
ATOM   6735 O  OD2 . ASP C 1 274 ? -68.033 9.149   34.375  1   30.55  ? 270 ASP C OD2 1 
ATOM   6736 N  N   . PRO C 1 275 ? -63.095 9.958   34.689  1   31.23  ? 271 PRO C N   1 
ATOM   6737 C  CA  . PRO C 1 275 ? -62.058 9.371   33.839  1   33.05  ? 271 PRO C CA  1 
ATOM   6738 C  C   . PRO C 1 275 ? -62.612 8.758   32.553  1   36.51  ? 271 PRO C C   1 
ATOM   6739 O  O   . PRO C 1 275 ? -61.995 8.877   31.49   1   41.83  ? 271 PRO C O   1 
ATOM   6740 C  CB  . PRO C 1 275 ? -61.474 8.285   34.741  1   31.66  ? 271 PRO C CB  1 
ATOM   6741 C  CG  . PRO C 1 275 ? -61.701 8.755   36.137  1   28.38  ? 271 PRO C CG  1 
ATOM   6742 C  CD  . PRO C 1 275 ? -62.989 9.532   36.094  1   29.66  ? 271 PRO C CD  1 
ATOM   6743 N  N   . ASN C 1 276 ? -63.778 8.103   32.669  1   34.96  ? 272 ASN C N   1 
ATOM   6744 C  CA  . ASN C 1 276 ? -64.393 7.389   31.558  1   30.43  ? 272 ASN C CA  1 
ATOM   6745 C  C   . ASN C 1 276 ? -64.794 8.36    30.441  1   30.37  ? 272 ASN C C   1 
ATOM   6746 O  O   . ASN C 1 276 ? -64.784 7.999   29.26   1   29.17  ? 272 ASN C O   1 
ATOM   6747 C  CB  . ASN C 1 276 ? -65.573 6.535   32.009  1   29.55  ? 272 ASN C CB  1 
ATOM   6748 C  CG  . ASN C 1 276 ? -65.208 5.454   33.004  1   30.47  ? 272 ASN C CG  1 
ATOM   6749 O  OD1 . ASN C 1 276 ? -64.243 4.7     32.835  1   31.04  ? 272 ASN C OD1 1 
ATOM   6750 N  ND2 . ASN C 1 276 ? -65.994 5.349   34.059  1   33.95  ? 272 ASN C ND2 1 
ATOM   6751 N  N   . LYS C 1 277 ? -65.132 9.602   30.811  1   31.37  ? 273 LYS C N   1 
ATOM   6752 C  CA  . LYS C 1 277 ? -65.677 10.55   29.854  1   30.53  ? 273 LYS C CA  1 
ATOM   6753 C  C   . LYS C 1 277 ? -64.581 11.473  29.336  1   27.76  ? 273 LYS C C   1 
ATOM   6754 O  O   . LYS C 1 277 ? -64.812 12.18   28.356  1   28.21  ? 273 LYS C O   1 
ATOM   6755 C  CB  . LYS C 1 277 ? -66.784 11.395  30.487  1   34.08  ? 273 LYS C CB  1 
ATOM   6756 C  CG  . LYS C 1 277 ? -68.048 10.636  30.861  1   43.63  ? 273 LYS C CG  1 
ATOM   6757 C  CD  . LYS C 1 277 ? -69.173 11.439  31.52   1   49.4   ? 273 LYS C CD  1 
ATOM   6758 C  CE  . LYS C 1 277 ? -70.39  10.576  31.824  1   48.37  ? 273 LYS C CE  1 
ATOM   6759 N  NZ  . LYS C 1 277 ? -71.489 11.305  32.48   1   46.53  ? 273 LYS C NZ  1 
ATOM   6760 N  N   . ARG C 1 278 ? -63.425 11.484  30.02   1   24.35  ? 274 ARG C N   1 
ATOM   6761 C  CA  . ARG C 1 278 ? -62.305 12.347  29.669  1   22.14  ? 274 ARG C CA  1 
ATOM   6762 C  C   . ARG C 1 278 ? -61.743 11.859  28.332  1   22.76  ? 274 ARG C C   1 
ATOM   6763 O  O   . ARG C 1 278 ? -61.581 10.651  28.13   1   22.74  ? 274 ARG C O   1 
ATOM   6764 C  CB  . ARG C 1 278 ? -61.289 12.311  30.814  1   19.73  ? 274 ARG C CB  1 
ATOM   6765 C  CG  . ARG C 1 278 ? -60.17  13.338  30.774  1   19.87  ? 274 ARG C CG  1 
ATOM   6766 C  CD  . ARG C 1 278 ? -59.215 13.219  31.97   1   19.77  ? 274 ARG C CD  1 
ATOM   6767 N  NE  . ARG C 1 278 ? -59.936 13.376  33.24   1   20     ? 274 ARG C NE  1 
ATOM   6768 C  CZ  . ARG C 1 278 ? -59.687 12.73   34.382  1   18.55  ? 274 ARG C CZ  1 
ATOM   6769 N  NH1 . ARG C 1 278 ? -58.587 12.03   34.525  1   16.59  ? 274 ARG C NH1 1 
ATOM   6770 N  NH2 . ARG C 1 278 ? -60.512 12.844  35.409  1   18.41  ? 274 ARG C NH2 1 
ATOM   6771 N  N   . ILE C 1 279 ? -61.453 12.812  27.441  1   22.06  ? 275 ILE C N   1 
ATOM   6772 C  CA  . ILE C 1 279 ? -61.019 12.534  26.081  1   23.03  ? 275 ILE C CA  1 
ATOM   6773 C  C   . ILE C 1 279 ? -59.682 11.788  26.1    1   25.48  ? 275 ILE C C   1 
ATOM   6774 O  O   . ILE C 1 279 ? -58.819 12.034  26.945  1   24.96  ? 275 ILE C O   1 
ATOM   6775 C  CB  . ILE C 1 279 ? -60.911 13.837  25.27   1   22     ? 275 ILE C CB  1 
ATOM   6776 C  CG1 . ILE C 1 279 ? -60.969 13.587  23.761  1   22.06  ? 275 ILE C CG1 1 
ATOM   6777 C  CG2 . ILE C 1 279 ? -59.666 14.635  25.658  1   22.95  ? 275 ILE C CG2 1 
ATOM   6778 C  CD1 . ILE C 1 279 ? -60.925 14.858  22.922  1   20.44  ? 275 ILE C CD1 1 
ATOM   6779 N  N   . SER C 1 280 ? -59.524 10.87   25.148  1   25.18  ? 276 SER C N   1 
ATOM   6780 C  CA  . SER C 1 280 ? -58.252 10.2    24.951  1   26.86  ? 276 SER C CA  1 
ATOM   6781 C  C   . SER C 1 280 ? -57.327 11.117  24.154  1   28.11  ? 276 SER C C   1 
ATOM   6782 O  O   . SER C 1 280 ? -57.803 12.005  23.441  1   26.6   ? 276 SER C O   1 
ATOM   6783 C  CB  . SER C 1 280 ? -58.454 8.919   24.203  1   28.56  ? 276 SER C CB  1 
ATOM   6784 O  OG  . SER C 1 280 ? -58.901 9.189   22.878  1   30.09  ? 276 SER C OG  1 
ATOM   6785 N  N   . ALA C 1 281 ? -56.012 10.857  24.261  1   28.01  ? 277 ALA C N   1 
ATOM   6786 C  CA  . ALA C 1 281 ? -55.006 11.546  23.465  1   27.2   ? 277 ALA C CA  1 
ATOM   6787 C  C   . ALA C 1 281 ? -55.298 11.31   21.983  1   27.49  ? 277 ALA C C   1 
ATOM   6788 O  O   . ALA C 1 281 ? -55.2   12.224  21.169  1   27.33  ? 277 ALA C O   1 
ATOM   6789 C  CB  . ALA C 1 281 ? -53.618 11.068  23.843  1   25.31  ? 277 ALA C CB  1 
ATOM   6790 N  N   . LYS C 1 282 ? -55.679 10.075  21.65   1   27.06  ? 278 LYS C N   1 
ATOM   6791 C  CA  . LYS C 1 282 ? -56.059 9.693   20.298  1   31.21  ? 278 LYS C CA  1 
ATOM   6792 C  C   . LYS C 1 282 ? -57.238 10.539  19.802  1   32.04  ? 278 LYS C C   1 
ATOM   6793 O  O   . LYS C 1 282 ? -57.147 11.185  18.759  1   32.5   ? 278 LYS C O   1 
ATOM   6794 C  CB  . LYS C 1 282 ? -56.348 8.187   20.282  1   34.15  ? 278 LYS C CB  1 
ATOM   6795 C  CG  . LYS C 1 282 ? -56.187 7.506   18.934  1   38.38  ? 278 LYS C CG  1 
ATOM   6796 C  CD  . LYS C 1 282 ? -56.484 6.007   18.889  1   42.9   ? 278 LYS C CD  1 
ATOM   6797 C  CE  . LYS C 1 282 ? -55.353 5.114   19.309  1   44.43  ? 278 LYS C CE  1 
ATOM   6798 N  NZ  . LYS C 1 282 ? -55.692 3.687   19.233  1   40.99  ? 278 LYS C NZ  1 
ATOM   6799 N  N   . ALA C 1 283 ? -58.35  10.547  20.548  1   32.64  ? 279 ALA C N   1 
ATOM   6800 C  CA  . ALA C 1 283 ? -59.507 11.357  20.178  1   31.13  ? 279 ALA C CA  1 
ATOM   6801 C  C   . ALA C 1 283 ? -59.142 12.84   20.074  1   30.31  ? 279 ALA C C   1 
ATOM   6802 O  O   . ALA C 1 283 ? -59.508 13.503  19.105  1   33.14  ? 279 ALA C O   1 
ATOM   6803 C  CB  . ALA C 1 283 ? -60.656 11.137  21.138  1   31.88  ? 279 ALA C CB  1 
ATOM   6804 N  N   . ALA C 1 284 ? -58.44  13.362  21.086  1   27.73  ? 280 ALA C N   1 
ATOM   6805 C  CA  . ALA C 1 284 ? -58.008 14.749  21.102  1   28.08  ? 280 ALA C CA  1 
ATOM   6806 C  C   . ALA C 1 284 ? -57.346 15.14   19.783  1   32.88  ? 280 ALA C C   1 
ATOM   6807 O  O   . ALA C 1 284 ? -57.61  16.226  19.265  1   35.23  ? 280 ALA C O   1 
ATOM   6808 C  CB  . ALA C 1 284 ? -57.088 14.993  22.264  1   28.63  ? 280 ALA C CB  1 
ATOM   6809 N  N   . LEU C 1 285 ? -56.497 14.252  19.238  1   35.92  ? 281 LEU C N   1 
ATOM   6810 C  CA  . LEU C 1 285 ? -55.75  14.522  18.016  1   34.47  ? 281 LEU C CA  1 
ATOM   6811 C  C   . LEU C 1 285 ? -56.673 14.877  16.848  1   35.5   ? 281 LEU C C   1 
ATOM   6812 O  O   . LEU C 1 285 ? -56.272 15.629  15.958  1   37.35  ? 281 LEU C O   1 
ATOM   6813 C  CB  . LEU C 1 285 ? -54.824 13.359  17.673  1   34.41  ? 281 LEU C CB  1 
ATOM   6814 C  CG  . LEU C 1 285 ? -53.589 13.189  18.565  1   33.91  ? 281 LEU C CG  1 
ATOM   6815 C  CD1 . LEU C 1 285 ? -52.906 11.858  18.246  1   31.91  ? 281 LEU C CD1 1 
ATOM   6816 C  CD2 . LEU C 1 285 ? -52.629 14.371  18.422  1   29.23  ? 281 LEU C CD2 1 
ATOM   6817 N  N   . ALA C 1 286 ? -57.902 14.343  16.862  1   34.5   ? 282 ALA C N   1 
ATOM   6818 C  CA  . ALA C 1 286 ? -58.907 14.664  15.859  1   34.61  ? 282 ALA C CA  1 
ATOM   6819 C  C   . ALA C 1 286 ? -59.67  15.958  16.175  1   36.26  ? 282 ALA C C   1 
ATOM   6820 O  O   . ALA C 1 286 ? -60.456 16.405  15.332  1   35.2   ? 282 ALA C O   1 
ATOM   6821 C  CB  . ALA C 1 286 ? -59.86  13.498  15.701  1   34.36  ? 282 ALA C CB  1 
ATOM   6822 N  N   . HIS C 1 287 ? -59.451 16.561  17.363  1   32.77  ? 283 HIS C N   1 
ATOM   6823 C  CA  . HIS C 1 287 ? -60.277 17.685  17.789  1   29.6   ? 283 HIS C CA  1 
ATOM   6824 C  C   . HIS C 1 287 ? -60.175 18.853  16.806  1   29.97  ? 283 HIS C C   1 
ATOM   6825 O  O   . HIS C 1 287 ? -59.09  19.106  16.284  1   32.27  ? 283 HIS C O   1 
ATOM   6826 C  CB  . HIS C 1 287 ? -59.957 18.115  19.224  1   26.41  ? 283 HIS C CB  1 
ATOM   6827 C  CG  . HIS C 1 287 ? -60.981 19.047  19.803  1   25.65  ? 283 HIS C CG  1 
ATOM   6828 N  ND1 . HIS C 1 287 ? -61.105 20.362  19.399  1   24.39  ? 283 HIS C ND1 1 
ATOM   6829 C  CD2 . HIS C 1 287 ? -61.959 18.847  20.709  1   25.07  ? 283 HIS C CD2 1 
ATOM   6830 C  CE1 . HIS C 1 287 ? -62.105 20.93   20.053  1   24.39  ? 283 HIS C CE1 1 
ATOM   6831 N  NE2 . HIS C 1 287 ? -62.632 20.033  20.863  1   24.05  ? 283 HIS C NE2 1 
ATOM   6832 N  N   . PRO C 1 288 ? -61.294 19.575  16.512  1   29.11  ? 284 PRO C N   1 
ATOM   6833 C  CA  . PRO C 1 288 ? -61.274 20.742  15.618  1   28.27  ? 284 PRO C CA  1 
ATOM   6834 C  C   . PRO C 1 288 ? -60.249 21.835  15.917  1   29.5   ? 284 PRO C C   1 
ATOM   6835 O  O   . PRO C 1 288 ? -59.991 22.682  15.058  1   32.33  ? 284 PRO C O   1 
ATOM   6836 C  CB  . PRO C 1 288 ? -62.697 21.32   15.671  1   25.05  ? 284 PRO C CB  1 
ATOM   6837 C  CG  . PRO C 1 288 ? -63.554 20.173  16.126  1   25.62  ? 284 PRO C CG  1 
ATOM   6838 C  CD  . PRO C 1 288 ? -62.664 19.268  16.97   1   26.88  ? 284 PRO C CD  1 
ATOM   6839 N  N   . PHE C 1 289 ? -59.723 21.845  17.152  1   26.03  ? 285 PHE C N   1 
ATOM   6840 C  CA  . PHE C 1 289 ? -58.761 22.853  17.571  1   25.86  ? 285 PHE C CA  1 
ATOM   6841 C  C   . PHE C 1 289 ? -57.498 22.78   16.708  1   26.45  ? 285 PHE C C   1 
ATOM   6842 O  O   . PHE C 1 289 ? -56.87  23.814  16.457  1   23.89  ? 285 PHE C O   1 
ATOM   6843 C  CB  . PHE C 1 289 ? -58.467 22.684  19.063  1   24.69  ? 285 PHE C CB  1 
ATOM   6844 C  CG  . PHE C 1 289 ? -57.444 23.645  19.649  1   24.84  ? 285 PHE C CG  1 
ATOM   6845 C  CD1 . PHE C 1 289 ? -57.702 25.01   19.721  1   23.88  ? 285 PHE C CD1 1 
ATOM   6846 C  CD2 . PHE C 1 289 ? -56.238 23.164  20.154  1   25.42  ? 285 PHE C CD2 1 
ATOM   6847 C  CE1 . PHE C 1 289 ? -56.773 25.866  20.28   1   23.76  ? 285 PHE C CE1 1 
ATOM   6848 C  CE2 . PHE C 1 289 ? -55.308 24.023  20.711  1   25.71  ? 285 PHE C CE2 1 
ATOM   6849 C  CZ  . PHE C 1 289 ? -55.582 25.373  20.772  1   26.31  ? 285 PHE C CZ  1 
ATOM   6850 N  N   . PHE C 1 290 ? -57.154 21.555  16.263  1   27.21  ? 286 PHE C N   1 
ATOM   6851 C  CA  . PHE C 1 290 ? -55.9   21.254  15.584  1   27.74  ? 286 PHE C CA  1 
ATOM   6852 C  C   . PHE C 1 290 ? -56.05  21.278  14.058  1   30.27  ? 286 PHE C C   1 
ATOM   6853 O  O   . PHE C 1 290 ? -55.072 21.065  13.34   1   28.6   ? 286 PHE C O   1 
ATOM   6854 C  CB  . PHE C 1 290 ? -55.396 19.886  16.051  1   27.04  ? 286 PHE C CB  1 
ATOM   6855 C  CG  . PHE C 1 290 ? -55.075 19.803  17.533  1   25.84  ? 286 PHE C CG  1 
ATOM   6856 C  CD1 . PHE C 1 290 ? -54.138 20.661  18.107  1   24.67  ? 286 PHE C CD1 1 
ATOM   6857 C  CD2 . PHE C 1 290 ? -55.72  18.874  18.341  1   24.23  ? 286 PHE C CD2 1 
ATOM   6858 C  CE1 . PHE C 1 290 ? -53.838 20.58   19.453  1   24.26  ? 286 PHE C CE1 1 
ATOM   6859 C  CE2 . PHE C 1 290 ? -55.417 18.799  19.691  1   24.36  ? 286 PHE C CE2 1 
ATOM   6860 C  CZ  . PHE C 1 290 ? -54.483 19.654  20.244  1   23.99  ? 286 PHE C CZ  1 
ATOM   6861 N  N   . GLN C 1 291 ? -57.254 21.579  13.562  1   31.47  ? 287 GLN C N   1 
ATOM   6862 C  CA  . GLN C 1 291 ? -57.514 21.612  12.133  1   33.96  ? 287 GLN C CA  1 
ATOM   6863 C  C   . GLN C 1 291 ? -56.53  22.498  11.375  1   32.08  ? 287 GLN C C   1 
ATOM   6864 O  O   . GLN C 1 291 ? -56.224 22.22   10.223  1   34.49  ? 287 GLN C O   1 
ATOM   6865 C  CB  . GLN C 1 291 ? -58.973 21.933  11.827  1   38.26  ? 287 GLN C CB  1 
ATOM   6866 C  CG  . GLN C 1 291 ? -59.893 20.814  12.301  1   44.83  ? 287 GLN C CG  1 
ATOM   6867 C  CD  . GLN C 1 291 ? -61.135 20.645  11.459  1   52.9   ? 287 GLN C CD  1 
ATOM   6868 O  OE1 . GLN C 1 291 ? -61.955 21.562  11.303  1   52.31  ? 287 GLN C OE1 1 
ATOM   6869 N  NE2 . GLN C 1 291 ? -61.275 19.445  10.912  1   58.82  ? 287 GLN C NE2 1 
ATOM   6870 N  N   . ASP C 1 292 ? -56.006 23.539  12.016  1   31.92  ? 288 ASP C N   1 
ATOM   6871 C  CA  . ASP C 1 292 ? -55.054 24.413  11.342  1   32.72  ? 288 ASP C CA  1 
ATOM   6872 C  C   . ASP C 1 292 ? -53.691 24.377  12.031  1   32.79  ? 288 ASP C C   1 
ATOM   6873 O  O   . ASP C 1 292 ? -52.964 25.365  12.032  1   32.7   ? 288 ASP C O   1 
ATOM   6874 C  CB  . ASP C 1 292 ? -55.559 25.847  11.321  1   34.08  ? 288 ASP C CB  1 
ATOM   6875 C  CG  . ASP C 1 292 ? -55.986 26.381  12.683  1   32.29  ? 288 ASP C CG  1 
ATOM   6876 O  OD1 . ASP C 1 292 ? -55.86  25.621  13.665  1   30.75  ? 288 ASP C OD1 1 
ATOM   6877 O  OD2 . ASP C 1 292 ? -56.456 27.538  12.742  1   30.63  ? 288 ASP C OD2 1 
ATOM   6878 N  N   . VAL C 1 293 ? -53.337 23.24   12.627  1   32.78  ? 289 VAL C N   1 
ATOM   6879 C  CA  . VAL C 1 293 ? -52.096 23.192  13.371  1   34.63  ? 289 VAL C CA  1 
ATOM   6880 C  C   . VAL C 1 293 ? -50.926 23.299  12.396  1   38.54  ? 289 VAL C C   1 
ATOM   6881 O  O   . VAL C 1 293 ? -50.983 22.773  11.289  1   40.89  ? 289 VAL C O   1 
ATOM   6882 C  CB  . VAL C 1 293 ? -52.002 21.941  14.253  1   32.26  ? 289 VAL C CB  1 
ATOM   6883 C  CG1 . VAL C 1 293 ? -51.831 20.671  13.424  1   33.1   ? 289 VAL C CG1 1 
ATOM   6884 C  CG2 . VAL C 1 293 ? -50.917 22.096  15.31   1   27.89  ? 289 VAL C CG2 1 
ATOM   6885 N  N   . THR C 1 294 ? -49.898 24.049  12.81   1   39.74  ? 290 THR C N   1 
ATOM   6886 C  CA  . THR C 1 294 ? -48.656 24.201  12.068  1   36.58  ? 290 THR C CA  1 
ATOM   6887 C  C   . THR C 1 294 ? -47.533 23.955  13.068  1   34.79  ? 290 THR C C   1 
ATOM   6888 O  O   . THR C 1 294 ? -47.805 23.613  14.21   1   34.28  ? 290 THR C O   1 
ATOM   6889 C  CB  . THR C 1 294 ? -48.567 25.595  11.434  1   37.9   ? 290 THR C CB  1 
ATOM   6890 O  OG1 . THR C 1 294 ? -48.523 26.51   12.525  1   41.18  ? 290 THR C OG1 1 
ATOM   6891 C  CG2 . THR C 1 294 ? -49.737 25.947  10.526  1   33.07  ? 290 THR C CG2 1 
ATOM   6892 N  N   . LYS C 1 295 ? -46.285 24.138  12.635  1   34.8   ? 291 LYS C N   1 
ATOM   6893 C  CA  . LYS C 1 295 ? -45.119 23.924  13.471  1   34.16  ? 291 LYS C CA  1 
ATOM   6894 C  C   . LYS C 1 295 ? -44.236 25.174  13.449  1   36.68  ? 291 LYS C C   1 
ATOM   6895 O  O   . LYS C 1 295 ? -43.22  25.216  12.75   1   38.27  ? 291 LYS C O   1 
ATOM   6896 C  CB  . LYS C 1 295 ? -44.366 22.68   12.99   1   34.13  ? 291 LYS C CB  1 
ATOM   6897 C  CG  . LYS C 1 295 ? -43.234 22.257  13.923  1   39.26  ? 291 LYS C CG  1 
ATOM   6898 C  CD  . LYS C 1 295 ? -42.233 21.25   13.368  1   42.75  ? 291 LYS C CD  1 
ATOM   6899 C  CE  . LYS C 1 295 ? -41.612 20.436  14.485  1   49.26  ? 291 LYS C CE  1 
ATOM   6900 N  NZ  . LYS C 1 295 ? -40.374 19.751  14.091  1   49.79  ? 291 LYS C NZ  1 
ATOM   6901 N  N   . PRO C 1 296 ? -44.581 26.236  14.22   1   35.31  ? 292 PRO C N   1 
ATOM   6902 C  CA  . PRO C 1 296 ? -43.71  27.407  14.346  1   35.22  ? 292 PRO C CA  1 
ATOM   6903 C  C   . PRO C 1 296 ? -42.443 27.033  15.112  1   37.79  ? 292 PRO C C   1 
ATOM   6904 O  O   . PRO C 1 296 ? -42.409 26.006  15.789  1   38.08  ? 292 PRO C O   1 
ATOM   6905 C  CB  . PRO C 1 296 ? -44.528 28.429  15.151  1   35.19  ? 292 PRO C CB  1 
ATOM   6906 C  CG  . PRO C 1 296 ? -45.905 27.836  15.306  1   33.32  ? 292 PRO C CG  1 
ATOM   6907 C  CD  . PRO C 1 296 ? -45.81  26.355  15.014  1   32.3   ? 292 PRO C CD  1 
ATOM   6908 N  N   . VAL C 1 297 ? -41.414 27.88   15      1   39.22  ? 293 VAL C N   1 
ATOM   6909 C  CA  . VAL C 1 297 ? -40.243 27.811  15.865  1   39.22  ? 293 VAL C CA  1 
ATOM   6910 C  C   . VAL C 1 297 ? -40.524 28.702  17.084  1   37.35  ? 293 VAL C C   1 
ATOM   6911 O  O   . VAL C 1 297 ? -41.278 29.663  16.985  1   34.57  ? 293 VAL C O   1 
ATOM   6912 C  CB  . VAL C 1 297 ? -38.925 28.174  15.13   1   36.41  ? 293 VAL C CB  1 
ATOM   6913 C  CG1 . VAL C 1 297 ? -38.823 27.546  13.741  1   31.62  ? 293 VAL C CG1 1 
ATOM   6914 C  CG2 . VAL C 1 297 ? -38.708 29.675  15.015  1   35.87  ? 293 VAL C CG2 1 
ATOM   6915 N  N   . PRO C 1 298 ? -39.993 28.405  18.293  1   39.91  ? 294 PRO C N   1 
ATOM   6916 C  CA  . PRO C 1 298 ? -40.128 29.322  19.435  1   42.89  ? 294 PRO C CA  1 
ATOM   6917 C  C   . PRO C 1 298 ? -39.295 30.592  19.284  1   45.63  ? 294 PRO C C   1 
ATOM   6918 O  O   . PRO C 1 298 ? -38.397 30.627  18.458  1   48.87  ? 294 PRO C O   1 
ATOM   6919 C  CB  . PRO C 1 298 ? -39.622 28.463  20.603  1   42.36  ? 294 PRO C CB  1 
ATOM   6920 C  CG  . PRO C 1 298 ? -38.635 27.5    19.973  1   42.62  ? 294 PRO C CG  1 
ATOM   6921 C  CD  . PRO C 1 298 ? -39.255 27.176  18.627  1   40.7   ? 294 PRO C CD  1 
ATOM   6922 N  N   . HIS C 1 299 ? -39.556 31.608  20.11   1   51.41  ? 295 HIS C N   1 
ATOM   6923 C  CA  . HIS C 1 299 ? -38.699 32.784  20.12   1   59.28  ? 295 HIS C CA  1 
ATOM   6924 C  C   . HIS C 1 299 ? -37.521 32.616  21.082  1   60.05  ? 295 HIS C C   1 
ATOM   6925 O  O   . HIS C 1 299 ? -37.701 32.683  22.293  1   60.26  ? 295 HIS C O   1 
ATOM   6926 C  CB  . HIS C 1 299 ? -39.523 34.065  20.288  1   70.95  ? 295 HIS C CB  1 
ATOM   6927 C  CG  . HIS C 1 299 ? -40.059 34.561  18.982  1   87.42  ? 295 HIS C CG  1 
ATOM   6928 N  ND1 . HIS C 1 299 ? -39.226 35.109  18.027  1   90.45  ? 295 HIS C ND1 1 
ATOM   6929 C  CD2 . HIS C 1 299 ? -41.295 34.57   18.445  1   93.36  ? 295 HIS C CD2 1 
ATOM   6930 C  CE1 . HIS C 1 299 ? -39.944 35.456  16.964  1   93.79  ? 295 HIS C CE1 1 
ATOM   6931 N  NE2 . HIS C 1 299 ? -41.204 35.141  17.198  1   94.55  ? 295 HIS C NE2 1 
ATOM   6932 N  N   . LEU C 1 300 ? -36.329 32.37   20.512  1   60.81  ? 296 LEU C N   1 
ATOM   6933 C  CA  . LEU C 1 300 ? -35.027 32.52   21.159  1   63.05  ? 296 LEU C CA  1 
ATOM   6934 C  C   . LEU C 1 300 ? -35.002 31.854  22.55   1   63.75  ? 296 LEU C C   1 
ATOM   6935 O  O   . LEU C 1 300 ? -35.092 30.604  22.607  1   60.17  ? 296 LEU C O   1 
ATOM   6936 C  CB  . LEU C 1 300 ? -34.604 33.991  21.23   1   65.87  ? 296 LEU C CB  1 
ATOM   6937 C  CG  . LEU C 1 300 ? -33.982 34.599  19.962  1   71.42  ? 296 LEU C CG  1 
ATOM   6938 C  CD1 . LEU C 1 300 ? -34.967 34.835  18.811  1   70.73  ? 296 LEU C CD1 1 
ATOM   6939 C  CD2 . LEU C 1 300 ? -33.215 35.88   20.271  1   65.07  ? 296 LEU C CD2 1 
ATOM   6940 N  N   . GLY D 2 1   ? -65.404 2.046   30.403  1   36.74  ? 171 GLY D N   1 
ATOM   6941 C  CA  . GLY D 2 1   ? -64.318 1.789   31.365  1   37.01  ? 171 GLY D CA  1 
ATOM   6942 C  C   . GLY D 2 1   ? -62.987 2.272   30.803  1   36.5   ? 171 GLY D C   1 
ATOM   6943 O  O   . GLY D 2 1   ? -62.402 1.571   29.987  1   36.11  ? 171 GLY D O   1 
ATOM   6944 N  N   . VAL D 2 2   ? -62.523 3.454   31.246  1   34.39  ? 172 VAL D N   1 
ATOM   6945 C  CA  . VAL D 2 2   ? -61.202 3.957   30.889  1   30.44  ? 172 VAL D CA  1 
ATOM   6946 C  C   . VAL D 2 2   ? -60.16  2.976   31.413  1   31     ? 172 VAL D C   1 
ATOM   6947 O  O   . VAL D 2 2   ? -59.03  2.965   30.928  1   32     ? 172 VAL D O   1 
ATOM   6948 C  CB  . VAL D 2 2   ? -60.887 5.39    31.365  1   28.16  ? 172 VAL D CB  1 
ATOM   6949 C  CG1 . VAL D 2 2   ? -60.715 5.48    32.879  1   27.12  ? 172 VAL D CG1 1 
ATOM   6950 C  CG2 . VAL D 2 2   ? -59.668 5.971   30.654  1   26.05  ? 172 VAL D CG2 1 
ATOM   6951 N  N   . ASN D 2 3   ? -60.57  2.173   32.408  1   32.39  ? 173 ASN D N   1 
ATOM   6952 C  CA  . ASN D 2 3   ? -59.74  1.16    33.048  1   30.87  ? 173 ASN D CA  1 
ATOM   6953 C  C   . ASN D 2 3   ? -59.475 -0.015  32.106  1   30.17  ? 173 ASN D C   1 
ATOM   6954 O  O   . ASN D 2 3   ? -58.601 -0.84   32.386  1   30.27  ? 173 ASN D O   1 
ATOM   6955 C  CB  . ASN D 2 3   ? -60.348 0.698   34.37   1   30.97  ? 173 ASN D CB  1 
ATOM   6956 C  CG  . ASN D 2 3   ? -60.356 1.774   35.431  1   33.8   ? 173 ASN D CG  1 
ATOM   6957 O  OD1 . ASN D 2 3   ? -59.577 2.738   35.392  1   36.34  ? 173 ASN D OD1 1 
ATOM   6958 N  ND2 . ASN D 2 3   ? -61.219 1.606   36.416  1   34.34  ? 173 ASN D ND2 1 
ATOM   6959 N  N   . GLU D 2 4   ? -60.254 -0.101  31.015  1   30.17  ? 174 GLU D N   1 
ATOM   6960 C  CA  . GLU D 2 4   ? -60.02  -1.087  29.969  1   32.34  ? 174 GLU D CA  1 
ATOM   6961 C  C   . GLU D 2 4   ? -59.531 -0.417  28.683  1   32.77  ? 174 GLU D C   1 
ATOM   6962 O  O   . GLU D 2 4   ? -59.6   -1.017  27.615  1   30.09  ? 174 GLU D O   1 
ATOM   6963 C  CB  . GLU D 2 4   ? -61.301 -1.875  29.71   1   33.59  ? 174 GLU D CB  1 
ATOM   6964 C  CG  . GLU D 2 4   ? -61.852 -2.59   30.942  1   34.93  ? 174 GLU D CG  1 
ATOM   6965 C  CD  . GLU D 2 4   ? -63.241 -3.13   30.685  1   39.07  ? 174 GLU D CD  1 
ATOM   6966 O  OE1 . GLU D 2 4   ? -63.814 -2.795  29.621  1   40.11  ? 174 GLU D OE1 1 
ATOM   6967 O  OE2 . GLU D 2 4   ? -63.74  -3.889  31.54   1   42.78  ? 174 GLU D OE2 1 
ATOM   6968 N  N   . VAL D 2 5   ? -59.021 0.823   28.801  1   34.62  ? 175 VAL D N   1 
ATOM   6969 C  CA  . VAL D 2 5   ? -58.417 1.598   27.718  1   31.62  ? 175 VAL D CA  1 
ATOM   6970 C  C   . VAL D 2 5   ? -59.073 1.216   26.391  1   29.31  ? 175 VAL D C   1 
ATOM   6971 O  O   . VAL D 2 5   ? -58.445 0.607   25.521  1   26.28  ? 175 VAL D O   1 
ATOM   6972 C  CB  . VAL D 2 5   ? -56.881 1.441   27.671  1   30.66  ? 175 VAL D CB  1 
ATOM   6973 C  CG1 . VAL D 2 5   ? -56.215 1.977   28.932  1   28.69  ? 175 VAL D CG1 1 
ATOM   6974 C  CG2 . VAL D 2 5   ? -56.459 -0.001  27.415  1   29.18  ? 175 VAL D CG2 1 
ATOM   6975 N  N   . PRO D 2 6   ? -60.372 1.545   26.215  1   27.9   ? 176 PRO D N   1 
ATOM   6976 C  CA  . PRO D 2 6   ? -61.077 1.296   24.959  1   27.51  ? 176 PRO D CA  1 
ATOM   6977 C  C   . PRO D 2 6   ? -60.42  1.883   23.712  1   28.66  ? 176 PRO D C   1 
ATOM   6978 O  O   . PRO D 2 6   ? -60.474 1.275   22.649  1   33.12  ? 176 PRO D O   1 
ATOM   6979 C  CB  . PRO D 2 6   ? -62.48  1.886   25.187  1   26.3   ? 176 PRO D CB  1 
ATOM   6980 C  CG  . PRO D 2 6   ? -62.348 2.763   26.407  1   26.34  ? 176 PRO D CG  1 
ATOM   6981 C  CD  . PRO D 2 6   ? -61.231 2.165   27.235  1   27.59  ? 176 PRO D CD  1 
ATOM   6982 N  N   . ASP D 2 7   ? -59.813 3.067   23.831  1   27.24  ? 177 ASP D N   1 
ATOM   6983 C  CA  . ASP D 2 7   ? -59.223 3.713   22.674  1   25.92  ? 177 ASP D CA  1 
ATOM   6984 C  C   . ASP D 2 7   ? -57.876 3.113   22.278  1   24.34  ? 177 ASP D C   1 
ATOM   6985 O  O   . ASP D 2 7   ? -57.335 3.554   21.263  1   23.2   ? 177 ASP D O   1 
ATOM   6986 C  CB  . ASP D 2 7   ? -59.108 5.213   22.861  1   27.78  ? 177 ASP D CB  1 
ATOM   6987 C  CG  . ASP D 2 7   ? -60.321 6.006   22.43   1   28.35  ? 177 ASP D CG  1 
ATOM   6988 O  OD1 . ASP D 2 7   ? -61.196 5.401   21.802  1   32.36  ? 177 ASP D OD1 1 
ATOM   6989 O  OD2 . ASP D 2 7   ? -60.38  7.207   22.736  1   29.59  ? 177 ASP D OD2 1 
ATOM   6990 N  N   . TYR D 2 8   ? -57.363 2.122   23.044  1   23.84  ? 178 TYR D N   1 
ATOM   6991 C  CA  . TYR D 2 8   ? -56.008 1.598   22.88   1   23.34  ? 178 TYR D CA  1 
ATOM   6992 C  C   . TYR D 2 8   ? -55.913 0.063   22.885  1   27.48  ? 178 TYR D C   1 
ATOM   6993 O  O   . TYR D 2 8   ? -54.886 -0.483  22.486  1   27.51  ? 178 TYR D O   1 
ATOM   6994 C  CB  . TYR D 2 8   ? -55.069 2.203   23.931  1   19.93  ? 178 TYR D CB  1 
ATOM   6995 C  CG  . TYR D 2 8   ? -54.917 3.711   23.832  1   18.95  ? 178 TYR D CG  1 
ATOM   6996 C  CD1 . TYR D 2 8   ? -54.172 4.302   22.82   1   17.97  ? 178 TYR D CD1 1 
ATOM   6997 C  CD2 . TYR D 2 8   ? -55.553 4.554   24.742  1   19.6   ? 178 TYR D CD2 1 
ATOM   6998 C  CE1 . TYR D 2 8   ? -54.074 5.683   22.724  1   18.6   ? 178 TYR D CE1 1 
ATOM   6999 C  CE2 . TYR D 2 8   ? -55.439 5.934   24.673  1   18.38  ? 178 TYR D CE2 1 
ATOM   7000 C  CZ  . TYR D 2 8   ? -54.707 6.506   23.649  1   18.61  ? 178 TYR D CZ  1 
ATOM   7001 O  OH  . TYR D 2 8   ? -54.616 7.876   23.563  1   18.09  ? 178 TYR D OH  1 
ATOM   7002 N  N   . HIS D 2 9   ? -56.95  -0.658  23.338  1   33     ? 179 HIS D N   1 
ATOM   7003 C  CA  . HIS D 2 9   ? -56.873 -2.101  23.577  1   35.43  ? 179 HIS D CA  1 
ATOM   7004 C  C   . HIS D 2 9   ? -56.316 -2.85   22.354  1   35.35  ? 179 HIS D C   1 
ATOM   7005 O  O   . HIS D 2 9   ? -55.643 -3.864  22.52   1   33.44  ? 179 HIS D O   1 
ATOM   7006 C  CB  . HIS D 2 9   ? -58.206 -2.659  24.121  1   38.05  ? 179 HIS D CB  1 
ATOM   7007 C  CG  . HIS D 2 9   ? -59.267 -2.885  23.073  1   45.65  ? 179 HIS D CG  1 
ATOM   7008 N  ND1 . HIS D 2 9   ? -60.207 -1.94   22.71   1   48.97  ? 179 HIS D ND1 1 
ATOM   7009 C  CD2 . HIS D 2 9   ? -59.502 -3.949  22.268  1   47.49  ? 179 HIS D CD2 1 
ATOM   7010 C  CE1 . HIS D 2 9   ? -60.98  -2.423  21.739  1   48.97  ? 179 HIS D CE1 1 
ATOM   7011 N  NE2 . HIS D 2 9   ? -60.566 -3.641  21.453  1   47.87  ? 179 HIS D NE2 1 
ATOM   7012 N  N   . GLU D 2 10  ? -56.63  -2.378  21.131  1   37.39  ? 180 GLU D N   1 
ATOM   7013 C  CA  . GLU D 2 10  ? -56.196 -3.018  19.893  1   36.81  ? 180 GLU D CA  1 
ATOM   7014 C  C   . GLU D 2 10  ? -54.73  -2.7    19.618  1   34     ? 180 GLU D C   1 
ATOM   7015 O  O   . GLU D 2 10  ? -53.916 -3.607  19.45   1   34.18  ? 180 GLU D O   1 
ATOM   7016 C  CB  . GLU D 2 10  ? -56.952 -2.539  18.656  1   41.31  ? 180 GLU D CB  1 
ATOM   7017 C  CG  . GLU D 2 10  ? -58.336 -3.152  18.454  1   51.86  ? 180 GLU D CG  1 
ATOM   7018 C  CD  . GLU D 2 10  ? -58.901 -2.523  17.186  1   62.34  ? 180 GLU D CD  1 
ATOM   7019 O  OE1 . GLU D 2 10  ? -58.217 -2.612  16.135  1   59.27  ? 180 GLU D OE1 1 
ATOM   7020 O  OE2 . GLU D 2 10  ? -59.997 -1.913  17.249  1   70.85  ? 180 GLU D OE2 1 
ATOM   7021 N  N   . ASP D 2 11  ? -54.407 -1.404  19.571  1   29.97  ? 181 ASP D N   1 
ATOM   7022 C  CA  . ASP D 2 11  ? -53.022 -0.981  19.487  1   28.75  ? 181 ASP D CA  1 
ATOM   7023 C  C   . ASP D 2 11  ? -52.177 -1.775  20.489  1   29.09  ? 181 ASP D C   1 
ATOM   7024 O  O   . ASP D 2 11  ? -51.111 -2.254  20.129  1   32.46  ? 181 ASP D O   1 
ATOM   7025 C  CB  . ASP D 2 11  ? -52.883 0.531   19.591  1   31.12  ? 181 ASP D CB  1 
ATOM   7026 C  CG  . ASP D 2 11  ? -53.404 1.352   18.416  1   35.76  ? 181 ASP D CG  1 
ATOM   7027 O  OD1 . ASP D 2 11  ? -53.961 0.738   17.472  1   35.32  ? 181 ASP D OD1 1 
ATOM   7028 O  OD2 . ASP D 2 11  ? -53.239 2.606   18.446  1   35.75  ? 181 ASP D OD2 1 
ATOM   7029 N  N   . ILE D 2 12  ? -52.643 -1.933  21.736  1   25.55  ? 182 ILE D N   1 
ATOM   7030 C  CA  . ILE D 2 12  ? -51.847 -2.587  22.765  1   26.28  ? 182 ILE D CA  1 
ATOM   7031 C  C   . ILE D 2 12  ? -51.698 -4.073  22.456  1   25.66  ? 182 ILE D C   1 
ATOM   7032 O  O   . ILE D 2 12  ? -50.587 -4.59   22.527  1   25.44  ? 182 ILE D O   1 
ATOM   7033 C  CB  . ILE D 2 12  ? -52.387 -2.336  24.19   1   27.13  ? 182 ILE D CB  1 
ATOM   7034 C  CG1 . ILE D 2 12  ? -52.085 -0.902  24.657  1   24.47  ? 182 ILE D CG1 1 
ATOM   7035 C  CG2 . ILE D 2 12  ? -51.83  -3.369  25.169  1   25.88  ? 182 ILE D CG2 1 
ATOM   7036 C  CD1 . ILE D 2 12  ? -52.97  -0.416  25.791  1   23.4   ? 182 ILE D CD1 1 
ATOM   7037 N  N   . HIS D 2 13  ? -52.809 -4.751  22.122  1   25.99  ? 183 HIS D N   1 
ATOM   7038 C  CA  . HIS D 2 13  ? -52.784 -6.167  21.759  1   24.12  ? 183 HIS D CA  1 
ATOM   7039 C  C   . HIS D 2 13  ? -51.796 -6.416  20.614  1   23.67  ? 183 HIS D C   1 
ATOM   7040 O  O   . HIS D 2 13  ? -50.908 -7.262  20.727  1   25.09  ? 183 HIS D O   1 
ATOM   7041 C  CB  . HIS D 2 13  ? -54.189 -6.689  21.442  1   25.32  ? 183 HIS D CB  1 
ATOM   7042 C  CG  . HIS D 2 13  ? -54.197 -8.13   21.046  1   27.5   ? 183 HIS D CG  1 
ATOM   7043 N  ND1 . HIS D 2 13  ? -54.131 -9.144  21.987  1   29.4   ? 183 HIS D ND1 1 
ATOM   7044 C  CD2 . HIS D 2 13  ? -54.19  -8.725  19.844  1   25.03  ? 183 HIS D CD2 1 
ATOM   7045 C  CE1 . HIS D 2 13  ? -54.085 -10.312 21.365  1   26.06  ? 183 HIS D CE1 1 
ATOM   7046 N  NE2 . HIS D 2 13  ? -54.116 -10.077 20.071  1   25.83  ? 183 HIS D NE2 1 
ATOM   7047 N  N   . THR D 2 14  ? -51.937 -5.645  19.524  1   22.95  ? 184 THR D N   1 
ATOM   7048 C  CA  . THR D 2 14  ? -51.085 -5.747  18.349  1   23.84  ? 184 THR D CA  1 
ATOM   7049 C  C   . THR D 2 14  ? -49.615 -5.627  18.746  1   28.19  ? 184 THR D C   1 
ATOM   7050 O  O   . THR D 2 14  ? -48.78  -6.353  18.225  1   32.9   ? 184 THR D O   1 
ATOM   7051 C  CB  . THR D 2 14  ? -51.45  -4.709  17.29   1   22.49  ? 184 THR D CB  1 
ATOM   7052 O  OG1 . THR D 2 14  ? -52.784 -4.97   16.85   1   23.6   ? 184 THR D OG1 1 
ATOM   7053 C  CG2 . THR D 2 14  ? -50.475 -4.743  16.128  1   19.57  ? 184 THR D CG2 1 
ATOM   7054 N  N   . TYR D 2 15  ? -49.313 -4.71   19.671  1   28.56  ? 185 TYR D N   1 
ATOM   7055 C  CA  . TYR D 2 15  ? -47.953 -4.452  20.106  1   28.01  ? 185 TYR D CA  1 
ATOM   7056 C  C   . TYR D 2 15  ? -47.443 -5.613  20.951  1   26.8   ? 185 TYR D C   1 
ATOM   7057 O  O   . TYR D 2 15  ? -46.339 -6.092  20.715  1   29.62  ? 185 TYR D O   1 
ATOM   7058 C  CB  . TYR D 2 15  ? -47.875 -3.108  20.827  1   29.36  ? 185 TYR D CB  1 
ATOM   7059 C  CG  . TYR D 2 15  ? -46.497 -2.777  21.362  1   30.5   ? 185 TYR D CG  1 
ATOM   7060 C  CD1 . TYR D 2 15  ? -45.437 -2.564  20.481  1   31.21  ? 185 TYR D CD1 1 
ATOM   7061 C  CD2 . TYR D 2 15  ? -46.264 -2.664  22.734  1   29.96  ? 185 TYR D CD2 1 
ATOM   7062 C  CE1 . TYR D 2 15  ? -44.169 -2.258  20.951  1   32.43  ? 185 TYR D CE1 1 
ATOM   7063 C  CE2 . TYR D 2 15  ? -45.003 -2.332  23.216  1   29.21  ? 185 TYR D CE2 1 
ATOM   7064 C  CZ  . TYR D 2 15  ? -43.961 -2.136  22.315  1   33.21  ? 185 TYR D CZ  1 
ATOM   7065 O  OH  . TYR D 2 15  ? -42.681 -1.821  22.653  1   40.53  ? 185 TYR D OH  1 
ATOM   7066 N  N   . LEU D 2 16  ? -48.25  -6.078  21.911  1   25.47  ? 186 LEU D N   1 
ATOM   7067 C  CA  . LEU D 2 16  ? -47.861 -7.199  22.765  1   23.21  ? 186 LEU D CA  1 
ATOM   7068 C  C   . LEU D 2 16  ? -47.522 -8.412  21.904  1   22.04  ? 186 LEU D C   1 
ATOM   7069 O  O   . LEU D 2 16  ? -46.578 -9.123  22.195  1   20.72  ? 186 LEU D O   1 
ATOM   7070 C  CB  . LEU D 2 16  ? -48.966 -7.521  23.767  1   23.65  ? 186 LEU D CB  1 
ATOM   7071 C  CG  . LEU D 2 16  ? -49.193 -6.486  24.871  1   26.14  ? 186 LEU D CG  1 
ATOM   7072 C  CD1 . LEU D 2 16  ? -50.386 -6.842  25.733  1   25.21  ? 186 LEU D CD1 1 
ATOM   7073 C  CD2 . LEU D 2 16  ? -47.939 -6.269  25.702  1   23.22  ? 186 LEU D CD2 1 
ATOM   7074 N  N   . ARG D 2 17  ? -48.206 -8.559  20.784  1   24.07  ? 187 ARG D N   1 
ATOM   7075 C  CA  . ARG D 2 17  ? -48.002 -9.751  19.932  1   27.51  ? 187 ARG D CA  1 
ATOM   7076 C  C   . ARG D 2 17  ? -46.643 -9.697  19.213  1   29.01  ? 187 ARG D C   1 
ATOM   7077 O  O   . ARG D 2 17  ? -46.047 -10.764 19.023  1   29.94  ? 187 ARG D O   1 
ATOM   7078 C  CB  . ARG D 2 17  ? -49.187 -9.851  18.965  1   23.63  ? 187 ARG D CB  1 
ATOM   7079 C  CG  . ARG D 2 17  ? -50.488 -10.3   19.61   1   23.5   ? 187 ARG D CG  1 
ATOM   7080 C  CD  . ARG D 2 17  ? -50.49  -11.782 19.911  1   23.6   ? 187 ARG D CD  1 
ATOM   7081 N  NE  . ARG D 2 17  ? -50.414 -12.6   18.697  1   25.23  ? 187 ARG D NE  1 
ATOM   7082 C  CZ  . ARG D 2 17  ? -51.433 -12.863 17.893  1   23.93  ? 187 ARG D CZ  1 
ATOM   7083 N  NH1 . ARG D 2 17  ? -52.67  -12.805 18.348  1   23.47  ? 187 ARG D NH1 1 
ATOM   7084 N  NH2 . ARG D 2 17  ? -51.207 -13.211 16.642  1   21.19  ? 187 ARG D NH2 1 
ATOM   7085 N  N   . GLU D 2 18  ? -46.186 -8.504  18.856  1   28.97  ? 188 GLU D N   1 
ATOM   7086 C  CA  . GLU D 2 18  ? -44.871 -8.362  18.197  1   31.46  ? 188 GLU D CA  1 
ATOM   7087 C  C   . GLU D 2 18  ? -43.781 -8.485  19.255  1   30.36  ? 188 GLU D C   1 
ATOM   7088 O  O   . GLU D 2 18  ? -42.746 -9.105  18.973  1   30.45  ? 188 GLU D O   1 
ATOM   7089 C  CB  . GLU D 2 18  ? -44.776 -6.986  17.546  1   34.8   ? 188 GLU D CB  1 
ATOM   7090 C  CG  . GLU D 2 18  ? -46     -6.592  16.731  1   40.74  ? 188 GLU D CG  1 
ATOM   7091 C  CD  . GLU D 2 18  ? -45.985 -5.11   16.412  1   46.62  ? 188 GLU D CD  1 
ATOM   7092 O  OE1 . GLU D 2 18  ? -46.835 -4.667  15.617  1   45.14  ? 188 GLU D OE1 1 
ATOM   7093 O  OE2 . GLU D 2 18  ? -45.114 -4.404  16.957  1   42.94  ? 188 GLU D OE2 1 
ATOM   7094 N  N   . MET D 2 19  ? -44.031 -7.916  20.422  1   29.38  ? 189 MET D N   1 
ATOM   7095 C  CA  . MET D 2 19  ? -43.035 -7.894  21.523  1   32.98  ? 189 MET D CA  1 
ATOM   7096 C  C   . MET D 2 19  ? -42.785 -9.322  22.028  1   34.16  ? 189 MET D C   1 
ATOM   7097 O  O   . MET D 2 19  ? -41.627 -9.621  22.388  1   33.57  ? 189 MET D O   1 
ATOM   7098 C  CB  . MET D 2 19  ? -43.535 -7.026  22.681  1   30.38  ? 189 MET D CB  1 
ATOM   7099 C  CG  . MET D 2 19  ? -43.388 -5.543  22.438  1   39.08  ? 189 MET D CG  1 
ATOM   7100 S  SD  . MET D 2 19  ? -41.752 -4.941  22.902  1   43.22  ? 189 MET D SD  1 
ATOM   7101 C  CE  . MET D 2 19  ? -41.416 -6.001  24.315  1   43.68  ? 189 MET D CE  1 
ATOM   7102 N  N   . GLU D 2 20  ? -43.82  -10.166 22.056  1   32.04  ? 190 GLU D N   1 
ATOM   7103 C  CA  . GLU D 2 20  ? -43.637 -11.499 22.61   1   30.7   ? 190 GLU D CA  1 
ATOM   7104 C  C   . GLU D 2 20  ? -42.792 -12.361 21.668  1   29.69  ? 190 GLU D C   1 
ATOM   7105 O  O   . GLU D 2 20  ? -42.158 -13.315 22.101  1   31.74  ? 190 GLU D O   1 
ATOM   7106 C  CB  . GLU D 2 20  ? -44.967 -12.182 22.913  1   29.7   ? 190 GLU D CB  1 
ATOM   7107 C  CG  . GLU D 2 20  ? -45.765 -12.484 21.651  1   27.51  ? 190 GLU D CG  1 
ATOM   7108 C  CD  . GLU D 2 20  ? -46.946 -13.402 21.887  1   29.49  ? 190 GLU D CD  1 
ATOM   7109 O  OE1 . GLU D 2 20  ? -47.143 -13.869 23.039  1   27.45  ? 190 GLU D OE1 1 
ATOM   7110 O  OE2 . GLU D 2 20  ? -47.667 -13.65  20.886  1   31.75  ? 190 GLU D OE2 1 
ATOM   7111 N  N   . VAL D 2 21  ? -42.772 -12.033 20.377  1   28.78  ? 191 VAL D N   1 
ATOM   7112 C  CA  . VAL D 2 21  ? -41.841 -12.667 19.46   1   30.41  ? 191 VAL D CA  1 
ATOM   7113 C  C   . VAL D 2 21  ? -40.414 -12.22  19.794  1   33.07  ? 191 VAL D C   1 
ATOM   7114 O  O   . VAL D 2 21  ? -39.497 -13.034 19.784  1   32.41  ? 191 VAL D O   1 
ATOM   7115 C  CB  . VAL D 2 21  ? -42.209 -12.382 17.987  1   30.15  ? 191 VAL D CB  1 
ATOM   7116 C  CG1 . VAL D 2 21  ? -41.096 -12.773 17.017  1   26.76  ? 191 VAL D CG1 1 
ATOM   7117 C  CG2 . VAL D 2 21  ? -43.525 -13.048 17.59   1   28.7   ? 191 VAL D CG2 1 
ATOM   7118 N  N   . LYS D 2 22  ? -40.226 -10.933 20.101  1   34.9   ? 192 LYS D N   1 
ATOM   7119 C  CA  . LYS D 2 22  ? -38.888 -10.423 20.371  1   40.99  ? 192 LYS D CA  1 
ATOM   7120 C  C   . LYS D 2 22  ? -38.35  -10.906 21.718  1   35.86  ? 192 LYS D C   1 
ATOM   7121 O  O   . LYS D 2 22  ? -37.167 -11.177 21.83   1   39.22  ? 192 LYS D O   1 
ATOM   7122 C  CB  . LYS D 2 22  ? -38.797 -8.905  20.172  1   55.81  ? 192 LYS D CB  1 
ATOM   7123 C  CG  . LYS D 2 22  ? -39.017 -8.415  18.72   1   71.98  ? 192 LYS D CG  1 
ATOM   7124 C  CD  . LYS D 2 22  ? -37.89  -8.654  17.714  1   80.07  ? 192 LYS D CD  1 
ATOM   7125 C  CE  . LYS D 2 22  ? -38.318 -8.699  16.275  1   85.1   ? 192 LYS D CE  1 
ATOM   7126 N  NZ  . LYS D 2 22  ? -38.361 -7.405  15.583  1   84.26  ? 192 LYS D NZ  1 
ATOM   7127 N  N   . CYS D 2 23  ? -39.206 -11.025 22.735  1   32.04  ? 193 CYS D N   1 
ATOM   7128 C  CA  . CYS D 2 23  ? -38.788 -11.485 24.055  1   34.16  ? 193 CYS D CA  1 
ATOM   7129 C  C   . CYS D 2 23  ? -38.886 -13.006 24.171  1   35.08  ? 193 CYS D C   1 
ATOM   7130 O  O   . CYS D 2 23  ? -38.908 -13.529 25.286  1   38.67  ? 193 CYS D O   1 
ATOM   7131 C  CB  . CYS D 2 23  ? -39.684 -10.97  25.189  1   32.9   ? 193 CYS D CB  1 
ATOM   7132 S  SG  . CYS D 2 23  ? -39.675 -9.167  25.411  1   39.95  ? 193 CYS D SG  1 
ATOM   7133 N  N   . LYS D 2 24  ? -38.999 -13.716 23.045  1   34.47  ? 194 LYS D N   1 
ATOM   7134 C  CA  . LYS D 2 24  ? -39.22  -15.149 23.149  1   35.59  ? 194 LYS D CA  1 
ATOM   7135 C  C   . LYS D 2 24  ? -37.887 -15.816 23.458  1   32.65  ? 194 LYS D C   1 
ATOM   7136 O  O   . LYS D 2 24  ? -36.896 -15.488 22.82   1   32.27  ? 194 LYS D O   1 
ATOM   7137 C  CB  . LYS D 2 24  ? -39.78  -15.766 21.865  1   37.67  ? 194 LYS D CB  1 
ATOM   7138 C  CG  . LYS D 2 24  ? -40.431 -17.128 22.079  1   38.34  ? 194 LYS D CG  1 
ATOM   7139 C  CD  . LYS D 2 24  ? -40.707 -17.89  20.792  1   44.64  ? 194 LYS D CD  1 
ATOM   7140 C  CE  . LYS D 2 24  ? -41.302 -19.239 21.101  1   54.92  ? 194 LYS D CE  1 
ATOM   7141 N  NZ  . LYS D 2 24  ? -41.973 -19.818 19.931  1   55.31  ? 194 LYS D NZ  1 
ATOM   7142 N  N   . PRO D 2 25  ? -37.83  -16.75  24.435  1   32.49  ? 195 PRO D N   1 
ATOM   7143 C  CA  . PRO D 2 25  ? -36.614 -17.542 24.684  1   34.52  ? 195 PRO D CA  1 
ATOM   7144 C  C   . PRO D 2 25  ? -36.263 -18.417 23.49   1   32.45  ? 195 PRO D C   1 
ATOM   7145 O  O   . PRO D 2 25  ? -37.105 -18.604 22.622  1   36.76  ? 195 PRO D O   1 
ATOM   7146 C  CB  . PRO D 2 25  ? -36.946 -18.409 25.914  1   33.35  ? 195 PRO D CB  1 
ATOM   7147 C  CG  . PRO D 2 25  ? -38.185 -17.753 26.51   1   33.86  ? 195 PRO D CG  1 
ATOM   7148 C  CD  . PRO D 2 25  ? -38.931 -17.08  25.359  1   31.83  ? 195 PRO D CD  1 
ATOM   7149 N  N   . LYS D 2 26  ? -35.05  -18.985 23.485  1   34.99  ? 196 LYS D N   1 
ATOM   7150 C  CA  . LYS D 2 26  ? -34.655 -19.989 22.502  1   36.86  ? 196 LYS D CA  1 
ATOM   7151 C  C   . LYS D 2 26  ? -35.33  -21.324 22.839  1   37.49  ? 196 LYS D C   1 
ATOM   7152 O  O   . LYS D 2 26  ? -35.178 -21.828 23.952  1   38.77  ? 196 LYS D O   1 
ATOM   7153 C  CB  . LYS D 2 26  ? -33.124 -20.067 22.41   1   39.53  ? 196 LYS D CB  1 
ATOM   7154 C  CG  . LYS D 2 26  ? -32.501 -19.156 21.354  1   49.99  ? 196 LYS D CG  1 
ATOM   7155 C  CD  . LYS D 2 26  ? -31.195 -18.447 21.721  1   65.54  ? 196 LYS D CD  1 
ATOM   7156 C  CE  . LYS D 2 26  ? -29.866 -19     21.262  1   64.62  ? 196 LYS D CE  1 
ATOM   7157 N  NZ  . LYS D 2 26  ? -29.285 -19.948 22.215  1   61.71  ? 196 LYS D NZ  1 
ATOM   7158 N  N   . VAL D 2 27  ? -36.052 -21.904 21.866  1   35.48  ? 197 VAL D N   1 
ATOM   7159 C  CA  . VAL D 2 27  ? -36.851 -23.106 22.072  1   32.67  ? 197 VAL D CA  1 
ATOM   7160 C  C   . VAL D 2 27  ? -35.964 -24.286 22.468  1   32.17  ? 197 VAL D C   1 
ATOM   7161 O  O   . VAL D 2 27  ? -36.368 -25.124 23.282  1   34.24  ? 197 VAL D O   1 
ATOM   7162 C  CB  . VAL D 2 27  ? -37.767 -23.458 20.883  1   30.22  ? 197 VAL D CB  1 
ATOM   7163 C  CG1 . VAL D 2 27  ? -38.409 -24.822 21.046  1   30.33  ? 197 VAL D CG1 1 
ATOM   7164 C  CG2 . VAL D 2 27  ? -38.86  -22.415 20.69   1   29.8   ? 197 VAL D CG2 1 
ATOM   7165 N  N   . GLY D 2 28  ? -34.751 -24.352 21.914  1   28.64  ? 198 GLY D N   1 
ATOM   7166 C  CA  . GLY D 2 28  ? -33.936 -25.524 22.19   1   31.85  ? 198 GLY D CA  1 
ATOM   7167 C  C   . GLY D 2 28  ? -32.93  -25.386 23.334  1   33.92  ? 198 GLY D C   1 
ATOM   7168 O  O   . GLY D 2 28  ? -32.065 -26.247 23.45   1   35.77  ? 198 GLY D O   1 
ATOM   7169 N  N   . TYR D 2 29  ? -33.062 -24.368 24.206  1   32.32  ? 199 TYR D N   1 
ATOM   7170 C  CA  . TYR D 2 29  ? -31.887 -23.842 24.891  1   29.2   ? 199 TYR D CA  1 
ATOM   7171 C  C   . TYR D 2 29  ? -31.315 -24.868 25.864  1   28.03  ? 199 TYR D C   1 
ATOM   7172 O  O   . TYR D 2 29  ? -30.107 -24.907 26.098  1   27.08  ? 199 TYR D O   1 
ATOM   7173 C  CB  . TYR D 2 29  ? -32.073 -22.453 25.518  1   27.28  ? 199 TYR D CB  1 
ATOM   7174 C  CG  . TYR D 2 29  ? -32.792 -22.401 26.859  1   26.1   ? 199 TYR D CG  1 
ATOM   7175 C  CD1 . TYR D 2 29  ? -32.23  -22.97  28.007  1   24.87  ? 199 TYR D CD1 1 
ATOM   7176 C  CD2 . TYR D 2 29  ? -34.011 -21.737 26.987  1   24.96  ? 199 TYR D CD2 1 
ATOM   7177 C  CE1 . TYR D 2 29  ? -32.877 -22.921 29.232  1   24.37  ? 199 TYR D CE1 1 
ATOM   7178 C  CE2 . TYR D 2 29  ? -34.656 -21.668 28.21   1   26.65  ? 199 TYR D CE2 1 
ATOM   7179 C  CZ  . TYR D 2 29  ? -34.085 -22.249 29.338  1   26.8   ? 199 TYR D CZ  1 
ATOM   7180 O  OH  . TYR D 2 29  ? -34.741 -22.152 30.536  1   27.06  ? 199 TYR D OH  1 
ATOM   7181 N  N   . MET D 2 30  ? -32.201 -25.676 26.447  1   28.7   ? 200 MET D N   1 
ATOM   7182 C  CA  . MET D 2 30  ? -31.824 -26.521 27.568  1   30.25  ? 200 MET D CA  1 
ATOM   7183 C  C   . MET D 2 30  ? -30.843 -27.615 27.112  1   33.16  ? 200 MET D C   1 
ATOM   7184 O  O   . MET D 2 30  ? -30.007 -28.088 27.888  1   29.6   ? 200 MET D O   1 
ATOM   7185 C  CB  . MET D 2 30  ? -33.089 -27.065 28.242  1   29.06  ? 200 MET D CB  1 
ATOM   7186 C  CG  . MET D 2 30  ? -32.811 -27.665 29.592  1   31.99  ? 200 MET D CG  1 
ATOM   7187 S  SD  . MET D 2 30  ? -31.982 -26.496 30.684  1   40.42  ? 200 MET D SD  1 
ATOM   7188 C  CE  . MET D 2 30  ? -33.372 -25.583 31.355  1   38.05  ? 200 MET D CE  1 
ATOM   7189 N  N   . LYS D 2 31  ? -30.941 -28.007 25.831  1   33.83  ? 201 LYS D N   1 
ATOM   7190 C  CA  . LYS D 2 31  ? -30.047 -28.995 25.251  1   36.55  ? 201 LYS D CA  1 
ATOM   7191 C  C   . LYS D 2 31  ? -28.625 -28.445 25.151  1   37.41  ? 201 LYS D C   1 
ATOM   7192 O  O   . LYS D 2 31  ? -27.685 -29.21  25.357  1   40.91  ? 201 LYS D O   1 
ATOM   7193 C  CB  . LYS D 2 31  ? -30.458 -29.452 23.849  1   41.42  ? 201 LYS D CB  1 
ATOM   7194 C  CG  . LYS D 2 31  ? -31.837 -30.062 23.695  1   47.11  ? 201 LYS D CG  1 
ATOM   7195 C  CD  . LYS D 2 31  ? -32.065 -30.564 22.271  1   57.64  ? 201 LYS D CD  1 
ATOM   7196 C  CE  . LYS D 2 31  ? -33.5   -30.691 21.829  1   57.67  ? 201 LYS D CE  1 
ATOM   7197 N  NZ  . LYS D 2 31  ? -34.073 -29.381 21.504  1   53.92  ? 201 LYS D NZ  1 
ATOM   7198 N  N   . LYS D 2 32  ? -28.476 -27.138 24.873  1   33.92  ? 202 LYS D N   1 
ATOM   7199 C  CA  . LYS D 2 32  ? -27.167 -26.519 24.724  1   34.37  ? 202 LYS D CA  1 
ATOM   7200 C  C   . LYS D 2 32  ? -26.611 -26.012 26.056  1   30.49  ? 202 LYS D C   1 
ATOM   7201 O  O   . LYS D 2 32  ? -25.542 -25.41  26.08   1   33.04  ? 202 LYS D O   1 
ATOM   7202 C  CB  . LYS D 2 32  ? -27.179 -25.347 23.74   1   41.32  ? 202 LYS D CB  1 
ATOM   7203 C  CG  . LYS D 2 32  ? -27.512 -25.683 22.304  1   51.26  ? 202 LYS D CG  1 
ATOM   7204 C  CD  . LYS D 2 32  ? -28.831 -25.076 21.837  1   62.09  ? 202 LYS D CD  1 
ATOM   7205 C  CE  . LYS D 2 32  ? -29.086 -25.275 20.37   1   67.99  ? 202 LYS D CE  1 
ATOM   7206 N  NZ  . LYS D 2 32  ? -29.933 -24.205 19.836  1   69.84  ? 202 LYS D NZ  1 
ATOM   7207 N  N   . GLN D 2 33  ? -27.359 -26.203 27.144  1   28.23  ? 203 GLN D N   1 
ATOM   7208 C  CA  . GLN D 2 33  ? -26.853 -25.994 28.494  1   26.18  ? 203 GLN D CA  1 
ATOM   7209 C  C   . GLN D 2 33  ? -26.237 -27.3   29.002  1   25     ? 203 GLN D C   1 
ATOM   7210 O  O   . GLN D 2 33  ? -26.967 -28.231 29.334  1   25.3   ? 203 GLN D O   1 
ATOM   7211 C  CB  . GLN D 2 33  ? -28     -25.666 29.45   1   23.94  ? 203 GLN D CB  1 
ATOM   7212 C  CG  . GLN D 2 33  ? -28.527 -24.248 29.331  1   23.57  ? 203 GLN D CG  1 
ATOM   7213 C  CD  . GLN D 2 33  ? -27.606 -23.241 29.99   1   24.07  ? 203 GLN D CD  1 
ATOM   7214 O  OE1 . GLN D 2 33  ? -26.65  -23.603 30.688  1   23.2   ? 203 GLN D OE1 1 
ATOM   7215 N  NE2 . GLN D 2 33  ? -27.879 -21.961 29.756  1   22.94  ? 203 GLN D NE2 1 
ATOM   7216 N  N   . PRO D 2 34  ? -24.892 -27.41  29.106  1   23.97  ? 204 PRO D N   1 
ATOM   7217 C  CA  . PRO D 2 34  ? -24.262 -28.688 29.443  1   23.48  ? 204 PRO D CA  1 
ATOM   7218 C  C   . PRO D 2 34  ? -24.537 -29.18  30.866  1   24.43  ? 204 PRO D C   1 
ATOM   7219 O  O   . PRO D 2 34  ? -24.425 -30.368 31.154  1   25.46  ? 204 PRO D O   1 
ATOM   7220 C  CB  . PRO D 2 34  ? -22.779 -28.441 29.149  1   20.82  ? 204 PRO D CB  1 
ATOM   7221 C  CG  . PRO D 2 34  ? -22.626 -26.971 29.425  1   24.95  ? 204 PRO D CG  1 
ATOM   7222 C  CD  . PRO D 2 34  ? -23.919 -26.315 28.941  1   25.09  ? 204 PRO D CD  1 
ATOM   7223 N  N   . ASP D 2 35  ? -24.955 -28.281 31.753  1   27     ? 205 ASP D N   1 
ATOM   7224 C  CA  . ASP D 2 35  ? -24.927 -28.684 33.135  1   30.26  ? 205 ASP D CA  1 
ATOM   7225 C  C   . ASP D 2 35  ? -26.265 -28.515 33.846  1   33.99  ? 205 ASP D C   1 
ATOM   7226 O  O   . ASP D 2 35  ? -26.359 -28.856 35.026  1   37.48  ? 205 ASP D O   1 
ATOM   7227 C  CB  . ASP D 2 35  ? -23.765 -28.064 33.877  1   34.71  ? 205 ASP D CB  1 
ATOM   7228 C  CG  . ASP D 2 35  ? -23.708 -28.605 35.287  1   41.91  ? 205 ASP D CG  1 
ATOM   7229 O  OD1 . ASP D 2 35  ? -23.937 -29.834 35.43   1   47.31  ? 205 ASP D OD1 1 
ATOM   7230 O  OD2 . ASP D 2 35  ? -23.523 -27.796 36.216  1   43.72  ? 205 ASP D OD2 1 
ATOM   7231 N  N   . ILE D 2 36  ? -27.291 -28.027 33.141  1   33.03  ? 206 ILE D N   1 
ATOM   7232 C  CA  . ILE D 2 36  ? -28.603 -27.874 33.755  1   29.87  ? 206 ILE D CA  1 
ATOM   7233 C  C   . ILE D 2 36  ? -29.664 -28.451 32.821  1   29.02  ? 206 ILE D C   1 
ATOM   7234 O  O   . ILE D 2 36  ? -29.432 -28.504 31.617  1   26.62  ? 206 ILE D O   1 
ATOM   7235 C  CB  . ILE D 2 36  ? -28.869 -26.404 34.131  1   31.68  ? 206 ILE D CB  1 
ATOM   7236 C  CG1 . ILE D 2 36  ? -28.864 -25.484 32.92   1   31.65  ? 206 ILE D CG1 1 
ATOM   7237 C  CG2 . ILE D 2 36  ? -27.864 -25.928 35.182  1   35.35  ? 206 ILE D CG2 1 
ATOM   7238 C  CD1 . ILE D 2 36  ? -28.988 -24.022 33.282  1   29.72  ? 206 ILE D CD1 1 
ATOM   7239 N  N   . THR D 2 37  ? -30.807 -28.877 33.404  1   28.36  ? 207 THR D N   1 
ATOM   7240 C  CA  . THR D 2 37  ? -31.855 -29.645 32.738  1   27.41  ? 207 THR D CA  1 
ATOM   7241 C  C   . THR D 2 37  ? -33.229 -29.01  32.94   1   28.35  ? 207 THR D C   1 
ATOM   7242 O  O   . THR D 2 37  ? -33.405 -28.19  33.836  1   26.81  ? 207 THR D O   1 
ATOM   7243 C  CB  . THR D 2 37  ? -31.885 -31.081 33.267  1   27.87  ? 207 THR D CB  1 
ATOM   7244 O  OG1 . THR D 2 37  ? -32.266 -30.99  34.642  1   29.38  ? 207 THR D OG1 1 
ATOM   7245 C  CG2 . THR D 2 37  ? -30.591 -31.832 33.012  1   23.01  ? 207 THR D CG2 1 
ATOM   7246 N  N   . ASN D 2 38  ? -34.217 -29.458 32.138  1   31.38  ? 208 ASN D N   1 
ATOM   7247 C  CA  . ASN D 2 38  ? -35.593 -28.993 32.263  1   33.67  ? 208 ASN D CA  1 
ATOM   7248 C  C   . ASN D 2 38  ? -36.101 -29.29  33.682  1   33.38  ? 208 ASN D C   1 
ATOM   7249 O  O   . ASN D 2 38  ? -36.961 -28.586 34.209  1   29.56  ? 208 ASN D O   1 
ATOM   7250 C  CB  . ASN D 2 38  ? -36.529 -29.62  31.229  1   33.09  ? 208 ASN D CB  1 
ATOM   7251 C  CG  . ASN D 2 38  ? -36.297 -29.235 29.778  1   38.04  ? 208 ASN D CG  1 
ATOM   7252 O  OD1 . ASN D 2 38  ? -36.087 -28.062 29.432  1   38.67  ? 208 ASN D OD1 1 
ATOM   7253 N  ND2 . ASN D 2 38  ? -36.391 -30.213 28.887  1   36.05  ? 208 ASN D ND2 1 
ATOM   7254 N  N   . SER D 2 39  ? -35.556 -30.351 34.298  1   31.81  ? 209 SER D N   1 
ATOM   7255 C  CA  . SER D 2 39  ? -35.985 -30.797 35.617  1   30.63  ? 209 SER D CA  1 
ATOM   7256 C  C   . SER D 2 39  ? -35.542 -29.801 36.685  1   28.93  ? 209 SER D C   1 
ATOM   7257 O  O   . SER D 2 39  ? -36.322 -29.454 37.576  1   27.23  ? 209 SER D O   1 
ATOM   7258 C  CB  . SER D 2 39  ? -35.448 -32.174 35.937  1   30.7   ? 209 SER D CB  1 
ATOM   7259 O  OG  . SER D 2 39  ? -35.683 -32.505 37.302  1   31.85  ? 209 SER D OG  1 
ATOM   7260 N  N   . MET D 2 40  ? -34.269 -29.399 36.599  1   25.45  ? 210 MET D N   1 
ATOM   7261 C  CA  . MET D 2 40  ? -33.722 -28.386 37.481  1   24.28  ? 210 MET D CA  1 
ATOM   7262 C  C   . MET D 2 40  ? -34.524 -27.102 37.359  1   23.93  ? 210 MET D C   1 
ATOM   7263 O  O   . MET D 2 40  ? -34.833 -26.478 38.366  1   26.32  ? 210 MET D O   1 
ATOM   7264 C  CB  . MET D 2 40  ? -32.275 -28.082 37.122  1   22.66  ? 210 MET D CB  1 
ATOM   7265 C  CG  . MET D 2 40  ? -31.399 -29.194 37.549  1   24.48  ? 210 MET D CG  1 
ATOM   7266 S  SD  . MET D 2 40  ? -29.778 -28.845 36.871  1   26     ? 210 MET D SD  1 
ATOM   7267 C  CE  . MET D 2 40  ? -29.073 -30.492 36.986  1   20.24  ? 210 MET D CE  1 
ATOM   7268 N  N   . ARG D 2 41  ? -34.872 -26.749 36.123  1   22.76  ? 211 ARG D N   1 
ATOM   7269 C  CA  . ARG D 2 41  ? -35.61  -25.535 35.835  1   23.57  ? 211 ARG D CA  1 
ATOM   7270 C  C   . ARG D 2 41  ? -36.967 -25.591 36.522  1   22.83  ? 211 ARG D C   1 
ATOM   7271 O  O   . ARG D 2 41  ? -37.376 -24.618 37.153  1   25.48  ? 211 ARG D O   1 
ATOM   7272 C  CB  . ARG D 2 41  ? -35.738 -25.332 34.32   1   24.56  ? 211 ARG D CB  1 
ATOM   7273 C  CG  . ARG D 2 41  ? -36.44  -24.044 33.915  1   23.78  ? 211 ARG D CG  1 
ATOM   7274 C  CD  . ARG D 2 41  ? -36.791 -24.044 32.444  1   23.29  ? 211 ARG D CD  1 
ATOM   7275 N  NE  . ARG D 2 41  ? -37.712 -22.973 32.053  1   23.62  ? 211 ARG D NE  1 
ATOM   7276 C  CZ  . ARG D 2 41  ? -39.004 -22.927 32.351  1   23.9   ? 211 ARG D CZ  1 
ATOM   7277 N  NH1 . ARG D 2 41  ? -39.57  -23.932 33.006  1   23.42  ? 211 ARG D NH1 1 
ATOM   7278 N  NH2 . ARG D 2 41  ? -39.715 -21.861 32.004  1   23.33  ? 211 ARG D NH2 1 
ATOM   7279 N  N   . ALA D 2 42  ? -37.647 -26.73  36.398  1   22.2   ? 212 ALA D N   1 
ATOM   7280 C  CA  . ALA D 2 42  ? -38.941 -26.915 37.026  1   23.87  ? 212 ALA D CA  1 
ATOM   7281 C  C   . ALA D 2 42  ? -38.829 -26.701 38.539  1   27.39  ? 212 ALA D C   1 
ATOM   7282 O  O   . ALA D 2 42  ? -39.704 -26.059 39.123  1   33.83  ? 212 ALA D O   1 
ATOM   7283 C  CB  . ALA D 2 42  ? -39.502 -28.274 36.694  1   22.17  ? 212 ALA D CB  1 
ATOM   7284 N  N   . ILE D 2 43  ? -37.755 -27.209 39.166  1   24.24  ? 213 ILE D N   1 
ATOM   7285 C  CA  . ILE D 2 43  ? -37.536 -26.999 40.59   1   23.67  ? 213 ILE D CA  1 
ATOM   7286 C  C   . ILE D 2 43  ? -37.372 -25.506 40.889  1   24.7   ? 213 ILE D C   1 
ATOM   7287 O  O   . ILE D 2 43  ? -37.908 -24.99  41.874  1   23.99  ? 213 ILE D O   1 
ATOM   7288 C  CB  . ILE D 2 43  ? -36.316 -27.807 41.044  1   23.67  ? 213 ILE D CB  1 
ATOM   7289 C  CG1 . ILE D 2 43  ? -36.576 -29.292 40.878  1   23.48  ? 213 ILE D CG1 1 
ATOM   7290 C  CG2 . ILE D 2 43  ? -35.929 -27.457 42.48   1   21.03  ? 213 ILE D CG2 1 
ATOM   7291 C  CD1 . ILE D 2 43  ? -35.339 -30.117 41.143  1   25.54  ? 213 ILE D CD1 1 
ATOM   7292 N  N   . LEU D 2 44  ? -36.65  -24.817 40.005  1   23.89  ? 214 LEU D N   1 
ATOM   7293 C  CA  . LEU D 2 44  ? -36.392 -23.403 40.161  1   24.7   ? 214 LEU D CA  1 
ATOM   7294 C  C   . LEU D 2 44  ? -37.718 -22.658 40.162  1   26.01  ? 214 LEU D C   1 
ATOM   7295 O  O   . LEU D 2 44  ? -37.996 -21.852 41.058  1   28.43  ? 214 LEU D O   1 
ATOM   7296 C  CB  . LEU D 2 44  ? -35.483 -22.911 39.035  1   25.1   ? 214 LEU D CB  1 
ATOM   7297 C  CG  . LEU D 2 44  ? -35.103 -21.427 39.114  1   23.18  ? 214 LEU D CG  1 
ATOM   7298 C  CD1 . LEU D 2 44  ? -34.427 -21.14  40.441  1   21.2   ? 214 LEU D CD1 1 
ATOM   7299 C  CD2 . LEU D 2 44  ? -34.226 -20.988 37.946  1   21.93  ? 214 LEU D CD2 1 
ATOM   7300 N  N   . VAL D 2 45  ? -38.515 -22.924 39.125  1   25.79  ? 215 VAL D N   1 
ATOM   7301 C  CA  . VAL D 2 45  ? -39.736 -22.163 38.906  1   24.92  ? 215 VAL D CA  1 
ATOM   7302 C  C   . VAL D 2 45  ? -40.726 -22.498 40.021  1   24.91  ? 215 VAL D C   1 
ATOM   7303 O  O   . VAL D 2 45  ? -41.461 -21.635 40.48   1   23.85  ? 215 VAL D O   1 
ATOM   7304 C  CB  . VAL D 2 45  ? -40.308 -22.374 37.49   1   22     ? 215 VAL D CB  1 
ATOM   7305 C  CG1 . VAL D 2 45  ? -41.59  -21.593 37.236  1   21.99  ? 215 VAL D CG1 1 
ATOM   7306 C  CG2 . VAL D 2 45  ? -39.276 -22.021 36.432  1   21.17  ? 215 VAL D CG2 1 
ATOM   7307 N  N   . ASP D 2 46  ? -40.738 -23.758 40.462  1   26.76  ? 216 ASP D N   1 
ATOM   7308 C  CA  . ASP D 2 46  ? -41.638 -24.149 41.535  1   28.07  ? 216 ASP D CA  1 
ATOM   7309 C  C   . ASP D 2 46  ? -41.285 -23.383 42.815  1   30.21  ? 216 ASP D C   1 
ATOM   7310 O  O   . ASP D 2 46  ? -42.175 -22.985 43.564  1   31.4   ? 216 ASP D O   1 
ATOM   7311 C  CB  . ASP D 2 46  ? -41.616 -25.645 41.774  1   24.74  ? 216 ASP D CB  1 
ATOM   7312 C  CG  . ASP D 2 46  ? -42.644 -26.117 42.79   1   25.19  ? 216 ASP D CG  1 
ATOM   7313 O  OD1 . ASP D 2 46  ? -43.816 -26.282 42.411  1   25.46  ? 216 ASP D OD1 1 
ATOM   7314 O  OD2 . ASP D 2 46  ? -42.28  -26.255 43.964  1   25.09  ? 216 ASP D OD2 1 
ATOM   7315 N  N   . TRP D 2 47  ? -39.978 -23.212 43.057  1   30.07  ? 217 TRP D N   1 
ATOM   7316 C  CA  . TRP D 2 47  ? -39.459 -22.43  44.165  1   29.38  ? 217 TRP D CA  1 
ATOM   7317 C  C   . TRP D 2 47  ? -39.899 -20.96  44.062  1   30.42  ? 217 TRP D C   1 
ATOM   7318 O  O   . TRP D 2 47  ? -40.377 -20.383 45.036  1   30.1   ? 217 TRP D O   1 
ATOM   7319 C  CB  . TRP D 2 47  ? -37.937 -22.621 44.269  1   27.86  ? 217 TRP D CB  1 
ATOM   7320 C  CG  . TRP D 2 47  ? -37.296 -21.726 45.299  1   30.32  ? 217 TRP D CG  1 
ATOM   7321 C  CD1 . TRP D 2 47  ? -37.407 -21.828 46.655  1   28.51  ? 217 TRP D CD1 1 
ATOM   7322 C  CD2 . TRP D 2 47  ? -36.456 -20.57  45.05   1   30.07  ? 217 TRP D CD2 1 
ATOM   7323 N  NE1 . TRP D 2 47  ? -36.688 -20.833 47.269  1   29.38  ? 217 TRP D NE1 1 
ATOM   7324 C  CE2 . TRP D 2 47  ? -36.101 -20.043 46.315  1   29.47  ? 217 TRP D CE2 1 
ATOM   7325 C  CE3 . TRP D 2 47  ? -35.968 -19.945 43.896  1   25.81  ? 217 TRP D CE3 1 
ATOM   7326 C  CZ2 . TRP D 2 47  ? -35.281 -18.926 46.455  1   28.17  ? 217 TRP D CZ2 1 
ATOM   7327 C  CZ3 . TRP D 2 47  ? -35.156 -18.843 44.043  1   26.82  ? 217 TRP D CZ3 1 
ATOM   7328 C  CH2 . TRP D 2 47  ? -34.819 -18.339 45.299  1   26.43  ? 217 TRP D CH2 1 
ATOM   7329 N  N   . LEU D 2 48  ? -39.781 -20.362 42.875  1   27.12  ? 218 LEU D N   1 
ATOM   7330 C  CA  . LEU D 2 48  ? -40.228 -18.994 42.641  1   28.46  ? 218 LEU D CA  1 
ATOM   7331 C  C   . LEU D 2 48  ? -41.717 -18.79  42.96   1   28.31  ? 218 LEU D C   1 
ATOM   7332 O  O   . LEU D 2 48  ? -42.102 -17.766 43.527  1   30.24  ? 218 LEU D O   1 
ATOM   7333 C  CB  . LEU D 2 48  ? -39.865 -18.57  41.209  1   28.15  ? 218 LEU D CB  1 
ATOM   7334 C  CG  . LEU D 2 48  ? -38.365 -18.379 40.931  1   28.66  ? 218 LEU D CG  1 
ATOM   7335 C  CD1 . LEU D 2 48  ? -38.141 -17.827 39.549  1   32.57  ? 218 LEU D CD1 1 
ATOM   7336 C  CD2 . LEU D 2 48  ? -37.597 -17.509 41.914  1   26.42  ? 218 LEU D CD2 1 
ATOM   7337 N  N   . VAL D 2 49  ? -42.568 -19.752 42.591  1   26.76  ? 219 VAL D N   1 
ATOM   7338 C  CA  . VAL D 2 49  ? -43.966 -19.751 43.005  1   28.52  ? 219 VAL D CA  1 
ATOM   7339 C  C   . VAL D 2 49  ? -44.085 -19.641 44.534  1   28.55  ? 219 VAL D C   1 
ATOM   7340 O  O   . VAL D 2 49  ? -44.868 -18.836 45.026  1   26.71  ? 219 VAL D O   1 
ATOM   7341 C  CB  . VAL D 2 49  ? -44.72  -20.986 42.455  1   29.56  ? 219 VAL D CB  1 
ATOM   7342 C  CG1 . VAL D 2 49  ? -46.086 -21.181 43.107  1   26.02  ? 219 VAL D CG1 1 
ATOM   7343 C  CG2 . VAL D 2 49  ? -44.855 -20.943 40.934  1   27.86  ? 219 VAL D CG2 1 
ATOM   7344 N  N   . GLU D 2 50  ? -43.313 -20.445 45.289  1   28.83  ? 220 GLU D N   1 
ATOM   7345 C  CA  . GLU D 2 50  ? -43.328 -20.352 46.747  1   32.48  ? 220 GLU D CA  1 
ATOM   7346 C  C   . GLU D 2 50  ? -42.933 -18.939 47.184  1   28.25  ? 220 GLU D C   1 
ATOM   7347 O  O   . GLU D 2 50  ? -43.596 -18.32  47.995  1   24.85  ? 220 GLU D O   1 
ATOM   7348 C  CB  . GLU D 2 50  ? -42.385 -21.312 47.482  1   35.15  ? 220 GLU D CB  1 
ATOM   7349 C  CG  . GLU D 2 50  ? -42.829 -22.771 47.519  1   40.38  ? 220 GLU D CG  1 
ATOM   7350 C  CD  . GLU D 2 50  ? -41.856 -23.707 48.224  1   45.89  ? 220 GLU D CD  1 
ATOM   7351 O  OE1 . GLU D 2 50  ? -42.288 -24.584 49.012  1   56.21  ? 220 GLU D OE1 1 
ATOM   7352 O  OE2 . GLU D 2 50  ? -40.641 -23.55  48.002  1   44.53  ? 220 GLU D OE2 1 
ATOM   7353 N  N   . VAL D 2 51  ? -41.818 -18.449 46.648  1   28.68  ? 221 VAL D N   1 
ATOM   7354 C  CA  . VAL D 2 51  ? -41.308 -17.139 46.998  1   27.52  ? 221 VAL D CA  1 
ATOM   7355 C  C   . VAL D 2 51  ? -42.417 -16.118 46.749  1   27.09  ? 221 VAL D C   1 
ATOM   7356 O  O   . VAL D 2 51  ? -42.716 -15.308 47.625  1   25.95  ? 221 VAL D O   1 
ATOM   7357 C  CB  . VAL D 2 51  ? -39.998 -16.867 46.231  1   25.33  ? 221 VAL D CB  1 
ATOM   7358 C  CG1 . VAL D 2 51  ? -39.555 -15.411 46.32   1   22.83  ? 221 VAL D CG1 1 
ATOM   7359 C  CG2 . VAL D 2 51  ? -38.903 -17.819 46.704  1   23.35  ? 221 VAL D CG2 1 
ATOM   7360 N  N   . GLY D 2 52  ? -43.087 -16.238 45.599  1   24.37  ? 222 GLY D N   1 
ATOM   7361 C  CA  . GLY D 2 52  ? -44.139 -15.306 45.239  1   24.94  ? 222 GLY D CA  1 
ATOM   7362 C  C   . GLY D 2 52  ? -45.324 -15.346 46.21   1   29.16  ? 222 GLY D C   1 
ATOM   7363 O  O   . GLY D 2 52  ? -46.047 -14.356 46.344  1   33.04  ? 222 GLY D O   1 
ATOM   7364 N  N   . GLU D 2 53  ? -45.554 -16.504 46.841  1   28.9   ? 223 GLU D N   1 
ATOM   7365 C  CA  . GLU D 2 53  ? -46.68  -16.698 47.736  1   29.13  ? 223 GLU D CA  1 
ATOM   7366 C  C   . GLU D 2 53  ? -46.29  -16.198 49.122  1   27.04  ? 223 GLU D C   1 
ATOM   7367 O  O   . GLU D 2 53  ? -47.098 -15.578 49.786  1   33.91  ? 223 GLU D O   1 
ATOM   7368 C  CB  . GLU D 2 53  ? -47.159 -18.153 47.663  1   32     ? 223 GLU D CB  1 
ATOM   7369 C  CG  . GLU D 2 53  ? -48.663 -18.297 47.427  1   37.78  ? 223 GLU D CG  1 
ATOM   7370 C  CD  . GLU D 2 53  ? -49.185 -17.44  46.276  1   43.46  ? 223 GLU D CD  1 
ATOM   7371 O  OE1 . GLU D 2 53  ? -48.378 -17.106 45.354  1   41.72  ? 223 GLU D OE1 1 
ATOM   7372 O  OE2 . GLU D 2 53  ? -50.394 -17.064 46.329  1   42.95  ? 223 GLU D OE2 1 
ATOM   7373 N  N   . GLU D 2 54  ? -45.036 -16.415 49.519  1   26.43  ? 224 GLU D N   1 
ATOM   7374 C  CA  . GLU D 2 54  ? -44.472 -15.969 50.784  1   27.05  ? 224 GLU D CA  1 
ATOM   7375 C  C   . GLU D 2 54  ? -44.355 -14.441 50.909  1   27.82  ? 224 GLU D C   1 
ATOM   7376 O  O   . GLU D 2 54  ? -44.44  -13.9   52.004  1   28.54  ? 224 GLU D O   1 
ATOM   7377 C  CB  . GLU D 2 54  ? -43.084 -16.588 50.889  1   31.55  ? 224 GLU D CB  1 
ATOM   7378 C  CG  . GLU D 2 54  ? -42.202 -15.921 51.939  1   40.56  ? 224 GLU D CG  1 
ATOM   7379 C  CD  . GLU D 2 54  ? -42.377 -16.615 53.28   1   48.88  ? 224 GLU D CD  1 
ATOM   7380 O  OE1 . GLU D 2 54  ? -43.502 -17.075 53.613  1   50.55  ? 224 GLU D OE1 1 
ATOM   7381 O  OE2 . GLU D 2 54  ? -41.366 -16.662 54.01   1   60.21  ? 224 GLU D OE2 1 
ATOM   7382 N  N   . TYR D 2 55  ? -44.092 -13.742 49.811  1   28.96  ? 225 TYR D N   1 
ATOM   7383 C  CA  . TYR D 2 55  ? -43.875 -12.306 49.821  1   29.96  ? 225 TYR D CA  1 
ATOM   7384 C  C   . TYR D 2 55  ? -45.081 -11.604 49.196  1   33.16  ? 225 TYR D C   1 
ATOM   7385 O  O   . TYR D 2 55  ? -45.037 -10.41  48.906  1   37.54  ? 225 TYR D O   1 
ATOM   7386 C  CB  . TYR D 2 55  ? -42.53  -12.048 49.124  1   30.25  ? 225 TYR D CB  1 
ATOM   7387 C  CG  . TYR D 2 55  ? -41.342 -12.405 50.009  1   29.19  ? 225 TYR D CG  1 
ATOM   7388 C  CD1 . TYR D 2 55  ? -41.034 -11.635 51.127  1   26.1   ? 225 TYR D CD1 1 
ATOM   7389 C  CD2 . TYR D 2 55  ? -40.545 -13.514 49.75   1   30.02  ? 225 TYR D CD2 1 
ATOM   7390 C  CE1 . TYR D 2 55  ? -39.983 -11.962 51.971  1   24.71  ? 225 TYR D CE1 1 
ATOM   7391 C  CE2 . TYR D 2 55  ? -39.498 -13.855 50.595  1   28.51  ? 225 TYR D CE2 1 
ATOM   7392 C  CZ  . TYR D 2 55  ? -39.207 -13.068 51.697  1   25.59  ? 225 TYR D CZ  1 
ATOM   7393 O  OH  . TYR D 2 55  ? -38.152 -13.318 52.52   1   26.71  ? 225 TYR D OH  1 
ATOM   7394 N  N   . LYS D 2 56  ? -46.165 -12.374 49.045  1   31.48  ? 226 LYS D N   1 
ATOM   7395 C  CA  . LYS D 2 56  ? -47.408 -11.973 48.403  1   31.08  ? 226 LYS D CA  1 
ATOM   7396 C  C   . LYS D 2 56  ? -47.147 -11.074 47.188  1   26.33  ? 226 LYS D C   1 
ATOM   7397 O  O   . LYS D 2 56  ? -47.726 -10.008 47.084  1   27.21  ? 226 LYS D O   1 
ATOM   7398 C  CB  . LYS D 2 56  ? -48.416 -11.479 49.451  1   31.51  ? 226 LYS D CB  1 
ATOM   7399 C  CG  . LYS D 2 56  ? -48.341 -12.35  50.678  1   37.11  ? 226 LYS D CG  1 
ATOM   7400 C  CD  . LYS D 2 56  ? -49.603 -12.703 51.434  1   43.73  ? 226 LYS D CD  1 
ATOM   7401 C  CE  . LYS D 2 56  ? -49.781 -11.656 52.496  1   47.67  ? 226 LYS D CE  1 
ATOM   7402 N  NZ  . LYS D 2 56  ? -50.965 -11.891 53.322  1   48.18  ? 226 LYS D NZ  1 
ATOM   7403 N  N   . LEU D 2 57  ? -46.328 -11.548 46.25   1   26.5   ? 227 LEU D N   1 
ATOM   7404 C  CA  . LEU D 2 57  ? -46.032 -10.849 45.003  1   28.54  ? 227 LEU D CA  1 
ATOM   7405 C  C   . LEU D 2 57  ? -47.159 -11.033 43.998  1   27.55  ? 227 LEU D C   1 
ATOM   7406 O  O   . LEU D 2 57  ? -47.886 -12.003 44.103  1   31.44  ? 227 LEU D O   1 
ATOM   7407 C  CB  . LEU D 2 57  ? -44.745 -11.417 44.41   1   26.81  ? 227 LEU D CB  1 
ATOM   7408 C  CG  . LEU D 2 57  ? -43.525 -11.339 45.332  1   27.17  ? 227 LEU D CG  1 
ATOM   7409 C  CD1 . LEU D 2 57  ? -42.325 -11.895 44.564  1   24.49  ? 227 LEU D CD1 1 
ATOM   7410 C  CD2 . LEU D 2 57  ? -43.284 -9.911  45.864  1   23.59  ? 227 LEU D CD2 1 
ATOM   7411 N  N   . GLN D 2 58  ? -47.254 -10.131 43.009  1   26.91  ? 228 GLN D N   1 
ATOM   7412 C  CA  . GLN D 2 58  ? -48.167 -10.285 41.881  1   27.94  ? 228 GLN D CA  1 
ATOM   7413 C  C   . GLN D 2 58  ? -47.813 -11.542 41.074  1   28.79  ? 228 GLN D C   1 
ATOM   7414 O  O   . GLN D 2 58  ? -46.656 -11.944 40.965  1   31.14  ? 228 GLN D O   1 
ATOM   7415 C  CB  . GLN D 2 58  ? -48.144 -9.046  40.982  1   27.38  ? 228 GLN D CB  1 
ATOM   7416 C  CG  . GLN D 2 58  ? -48.707 -7.792  41.632  1   29.62  ? 228 GLN D CG  1 
ATOM   7417 C  CD  . GLN D 2 58  ? -50.152 -7.967  42.033  1   30.31  ? 228 GLN D CD  1 
ATOM   7418 O  OE1 . GLN D 2 58  ? -51.034 -8.161  41.193  1   33.5   ? 228 GLN D OE1 1 
ATOM   7419 N  NE2 . GLN D 2 58  ? -50.398 -7.918  43.33   1   27.28  ? 228 GLN D NE2 1 
ATOM   7420 N  N   . ASN D 2 59  ? -48.835 -12.179 40.513  1   29.07  ? 229 ASN D N   1 
ATOM   7421 C  CA  . ASN D 2 59  ? -48.645 -13.282 39.589  1   26.98  ? 229 ASN D CA  1 
ATOM   7422 C  C   . ASN D 2 59  ? -47.841 -12.834 38.375  1   24.74  ? 229 ASN D C   1 
ATOM   7423 O  O   . ASN D 2 59  ? -47.032 -13.621 37.875  1   24.74  ? 229 ASN D O   1 
ATOM   7424 C  CB  . ASN D 2 59  ? -49.975 -13.893 39.184  1   28.97  ? 229 ASN D CB  1 
ATOM   7425 C  CG  . ASN D 2 59  ? -50.584 -14.656 40.328  1   34.37  ? 229 ASN D CG  1 
ATOM   7426 O  OD1 . ASN D 2 59  ? -49.868 -15.301 41.105  1   37.2   ? 229 ASN D OD1 1 
ATOM   7427 N  ND2 . ASN D 2 59  ? -51.901 -14.587 40.444  1   39.31  ? 229 ASN D ND2 1 
ATOM   7428 N  N   . GLU D 2 60  ? -48.071 -11.586 37.921  1   22.37  ? 230 GLU D N   1 
ATOM   7429 C  CA  . GLU D 2 60  ? -47.322 -11.002 36.816  1   24.01  ? 230 GLU D CA  1 
ATOM   7430 C  C   . GLU D 2 60  ? -45.813 -11.015 37.089  1   28.37  ? 230 GLU D C   1 
ATOM   7431 O  O   . GLU D 2 60  ? -45.033 -11.213 36.158  1   32.15  ? 230 GLU D O   1 
ATOM   7432 C  CB  . GLU D 2 60  ? -47.806 -9.576  36.582  1   23.74  ? 230 GLU D CB  1 
ATOM   7433 C  CG  . GLU D 2 60  ? -46.989 -8.819  35.537  1   24.38  ? 230 GLU D CG  1 
ATOM   7434 C  CD  . GLU D 2 60  ? -47.15  -9.35   34.123  1   25.19  ? 230 GLU D CD  1 
ATOM   7435 O  OE1 . GLU D 2 60  ? -48.103 -10.122 33.869  1   27.12  ? 230 GLU D OE1 1 
ATOM   7436 O  OE2 . GLU D 2 60  ? -46.316 -8.99   33.292  1   24.61  ? 230 GLU D OE2 1 
ATOM   7437 N  N   . THR D 2 61  ? -45.403 -10.779 38.352  1   27.73  ? 231 THR D N   1 
ATOM   7438 C  CA  . THR D 2 61  ? -44.006 -10.747 38.769  1   26.71  ? 231 THR D CA  1 
ATOM   7439 C  C   . THR D 2 61  ? -43.376 -12.118 38.508  1   25.71  ? 231 THR D C   1 
ATOM   7440 O  O   . THR D 2 61  ? -42.353 -12.197 37.841  1   29.49  ? 231 THR D O   1 
ATOM   7441 C  CB  . THR D 2 61  ? -43.844 -10.238 40.215  1   25.72  ? 231 THR D CB  1 
ATOM   7442 O  OG1 . THR D 2 61  ? -44.426 -8.935  40.237  1   26.5   ? 231 THR D OG1 1 
ATOM   7443 C  CG2 . THR D 2 61  ? -42.398 -10.045 40.654  1   23.97  ? 231 THR D CG2 1 
ATOM   7444 N  N   . LEU D 2 62  ? -43.98  -13.187 39.029  1   24.82  ? 232 LEU D N   1 
ATOM   7445 C  CA  . LEU D 2 62  ? -43.56  -14.554 38.757  1   24.59  ? 232 LEU D CA  1 
ATOM   7446 C  C   . LEU D 2 62  ? -43.435 -14.822 37.255  1   24.43  ? 232 LEU D C   1 
ATOM   7447 O  O   . LEU D 2 62  ? -42.484 -15.467 36.823  1   26.44  ? 232 LEU D O   1 
ATOM   7448 C  CB  . LEU D 2 62  ? -44.566 -15.498 39.413  1   24.1   ? 232 LEU D CB  1 
ATOM   7449 C  CG  . LEU D 2 62  ? -44.4   -16.979 39.07   1   24.41  ? 232 LEU D CG  1 
ATOM   7450 C  CD1 . LEU D 2 62  ? -43.11  -17.576 39.583  1   23.6   ? 232 LEU D CD1 1 
ATOM   7451 C  CD2 . LEU D 2 62  ? -45.579 -17.752 39.581  1   25.22  ? 232 LEU D CD2 1 
ATOM   7452 N  N   . HIS D 2 63  ? -44.387 -14.339 36.445  1   25.36  ? 233 HIS D N   1 
ATOM   7453 C  CA  . HIS D 2 63  ? -44.322 -14.527 34.995  1   26.68  ? 233 HIS D CA  1 
ATOM   7454 C  C   . HIS D 2 63  ? -43.137 -13.793 34.359  1   26.88  ? 233 HIS D C   1 
ATOM   7455 O  O   . HIS D 2 63  ? -42.53  -14.319 33.423  1   28.8   ? 233 HIS D O   1 
ATOM   7456 C  CB  . HIS D 2 63  ? -45.626 -14.11  34.311  1   26.52  ? 233 HIS D CB  1 
ATOM   7457 C  CG  . HIS D 2 63  ? -46.694 -15.142 34.262  1   27     ? 233 HIS D CG  1 
ATOM   7458 N  ND1 . HIS D 2 63  ? -47.54  -15.392 35.33   1   27.29  ? 233 HIS D ND1 1 
ATOM   7459 C  CD2 . HIS D 2 63  ? -47.069 -15.95  33.269  1   24.7   ? 233 HIS D CD2 1 
ATOM   7460 C  CE1 . HIS D 2 63  ? -48.387 -16.344 34.989  1   25.39  ? 233 HIS D CE1 1 
ATOM   7461 N  NE2 . HIS D 2 63  ? -48.131 -16.68  33.744  1   24.68  ? 233 HIS D NE2 1 
ATOM   7462 N  N   . LEU D 2 64  ? -42.815 -12.59  34.866  1   24.98  ? 234 LEU D N   1 
ATOM   7463 C  CA  . LEU D 2 64  ? -41.718 -11.792 34.35   1   24.63  ? 234 LEU D CA  1 
ATOM   7464 C  C   . LEU D 2 64  ? -40.377 -12.45  34.693  1   29.24  ? 234 LEU D C   1 
ATOM   7465 O  O   . LEU D 2 64  ? -39.502 -12.568 33.821  1   31.55  ? 234 LEU D O   1 
ATOM   7466 C  CB  . LEU D 2 64  ? -41.832 -10.365 34.885  1   23.55  ? 234 LEU D CB  1 
ATOM   7467 C  CG  . LEU D 2 64  ? -42.932 -9.502  34.255  1   22.89  ? 234 LEU D CG  1 
ATOM   7468 C  CD1 . LEU D 2 64  ? -43.103 -8.258  35.073  1   22.15  ? 234 LEU D CD1 1 
ATOM   7469 C  CD2 . LEU D 2 64  ? -42.625 -9.095  32.832  1   20.51  ? 234 LEU D CD2 1 
ATOM   7470 N  N   . ALA D 2 65  ? -40.261 -12.968 35.939  1   27.07  ? 235 ALA D N   1 
ATOM   7471 C  CA  . ALA D 2 65  ? -39.022 -13.609 36.375  1   26.13  ? 235 ALA D CA  1 
ATOM   7472 C  C   . ALA D 2 65  ? -38.723 -14.83  35.498  1   25.71  ? 235 ALA D C   1 
ATOM   7473 O  O   . ALA D 2 65  ? -37.571 -15.044 35.143  1   26.65  ? 235 ALA D O   1 
ATOM   7474 C  CB  . ALA D 2 65  ? -39.069 -13.947 37.85   1   23.86  ? 235 ALA D CB  1 
ATOM   7475 N  N   . VAL D 2 66  ? -39.754 -15.606 35.12   1   24.95  ? 236 VAL D N   1 
ATOM   7476 C  CA  . VAL D 2 66  ? -39.553 -16.797 34.301  1   26.84  ? 236 VAL D CA  1 
ATOM   7477 C  C   . VAL D 2 66  ? -39.087 -16.407 32.894  1   28.26  ? 236 VAL D C   1 
ATOM   7478 O  O   . VAL D 2 66  ? -38.187 -17.049 32.331  1   27.63  ? 236 VAL D O   1 
ATOM   7479 C  CB  . VAL D 2 66  ? -40.792 -17.708 34.259  1   26.29  ? 236 VAL D CB  1 
ATOM   7480 C  CG1 . VAL D 2 66  ? -40.592 -18.86  33.288  1   25.25  ? 236 VAL D CG1 1 
ATOM   7481 C  CG2 . VAL D 2 66  ? -41.199 -18.207 35.645  1   26.72  ? 236 VAL D CG2 1 
ATOM   7482 N  N   . ASN D 2 67  ? -39.654 -15.307 32.361  1   25.94  ? 237 ASN D N   1 
ATOM   7483 C  CA  . ASN D 2 67  ? -39.235 -14.803 31.068  1   26.1   ? 237 ASN D CA  1 
ATOM   7484 C  C   . ASN D 2 67  ? -37.748 -14.434 31.115  1   29.19  ? 237 ASN D C   1 
ATOM   7485 O  O   . ASN D 2 67  ? -36.991 -14.749 30.193  1   28.38  ? 237 ASN D O   1 
ATOM   7486 C  CB  . ASN D 2 67  ? -40.117 -13.642 30.623  1   25.97  ? 237 ASN D CB  1 
ATOM   7487 C  CG  . ASN D 2 67  ? -39.71  -13.139 29.26   1   27.65  ? 237 ASN D CG  1 
ATOM   7488 O  OD1 . ASN D 2 67  ? -38.965 -12.156 29.162  1   30.54  ? 237 ASN D OD1 1 
ATOM   7489 N  ND2 . ASN D 2 67  ? -40.119 -13.836 28.208  1   26.33  ? 237 ASN D ND2 1 
ATOM   7490 N  N   . TYR D 2 68  ? -37.343 -13.774 32.214  1   30.95  ? 238 TYR D N   1 
ATOM   7491 C  CA  . TYR D 2 68  ? -35.994 -13.25  32.389  1   30.94  ? 238 TYR D CA  1 
ATOM   7492 C  C   . TYR D 2 68  ? -34.979 -14.39  32.427  1   31.77  ? 238 TYR D C   1 
ATOM   7493 O  O   . TYR D 2 68  ? -33.946 -14.29  31.763  1   35.15  ? 238 TYR D O   1 
ATOM   7494 C  CB  . TYR D 2 68  ? -35.86  -12.353 33.625  1   30.64  ? 238 TYR D CB  1 
ATOM   7495 C  CG  . TYR D 2 68  ? -36.761 -11.127 33.654  1   27.18  ? 238 TYR D CG  1 
ATOM   7496 C  CD1 . TYR D 2 68  ? -37.381 -10.676 32.491  1   25.9   ? 238 TYR D CD1 1 
ATOM   7497 C  CD2 . TYR D 2 68  ? -37.025 -10.465 34.849  1   25.73  ? 238 TYR D CD2 1 
ATOM   7498 C  CE1 . TYR D 2 68  ? -38.237 -9.59   32.499  1   26.68  ? 238 TYR D CE1 1 
ATOM   7499 C  CE2 . TYR D 2 68  ? -37.863 -9.362  34.869  1   26.99  ? 238 TYR D CE2 1 
ATOM   7500 C  CZ  . TYR D 2 68  ? -38.467 -8.928  33.693  1   27.67  ? 238 TYR D CZ  1 
ATOM   7501 O  OH  . TYR D 2 68  ? -39.316 -7.866  33.652  1   27.13  ? 238 TYR D OH  1 
ATOM   7502 N  N   . ILE D 2 69  ? -35.293 -15.452 33.189  1   27.85  ? 239 ILE D N   1 
ATOM   7503 C  CA  . ILE D 2 69  ? -34.472 -16.654 33.294  1   28.57  ? 239 ILE D CA  1 
ATOM   7504 C  C   . ILE D 2 69  ? -34.307 -17.368 31.945  1   31.05  ? 239 ILE D C   1 
ATOM   7505 O  O   . ILE D 2 69  ? -33.178 -17.747 31.601  1   31.65  ? 239 ILE D O   1 
ATOM   7506 C  CB  . ILE D 2 69  ? -35.046 -17.604 34.361  1   26.52  ? 239 ILE D CB  1 
ATOM   7507 C  CG1 . ILE D 2 69  ? -35.001 -16.953 35.735  1   26.21  ? 239 ILE D CG1 1 
ATOM   7508 C  CG2 . ILE D 2 69  ? -34.312 -18.951 34.338  1   22.9   ? 239 ILE D CG2 1 
ATOM   7509 C  CD1 . ILE D 2 69  ? -36.059 -17.452 36.708  1   27.65  ? 239 ILE D CD1 1 
ATOM   7510 N  N   . ASP D 2 70  ? -35.423 -17.62  31.226  1   29.65  ? 240 ASP D N   1 
ATOM   7511 C  CA  . ASP D 2 70  ? -35.368 -18.383 29.985  1   30.11  ? 240 ASP D CA  1 
ATOM   7512 C  C   . ASP D 2 70  ? -34.519 -17.636 28.965  1   28.36  ? 240 ASP D C   1 
ATOM   7513 O  O   . ASP D 2 70  ? -33.737 -18.264 28.263  1   31.67  ? 240 ASP D O   1 
ATOM   7514 C  CB  . ASP D 2 70  ? -36.745 -18.822 29.506  1   33.33  ? 240 ASP D CB  1 
ATOM   7515 C  CG  . ASP D 2 70  ? -37.473 -19.781 30.439  1   34.47  ? 240 ASP D CG  1 
ATOM   7516 O  OD1 . ASP D 2 70  ? -36.788 -20.615 31.081  1   33.04  ? 240 ASP D OD1 1 
ATOM   7517 O  OD2 . ASP D 2 70  ? -38.715 -19.698 30.512  1   34.58  ? 240 ASP D OD2 1 
ATOM   7518 N  N   . ARG D 2 71  ? -34.619 -16.3   28.958  1   25.65  ? 241 ARG D N   1 
ATOM   7519 C  CA  . ARG D 2 71  ? -33.846 -15.479 28.029  1   26.64  ? 241 ARG D CA  1 
ATOM   7520 C  C   . ARG D 2 71  ? -32.372 -15.457 28.42   1   27.6   ? 241 ARG D C   1 
ATOM   7521 O  O   . ARG D 2 71  ? -31.506 -15.507 27.543  1   30.63  ? 241 ARG D O   1 
ATOM   7522 C  CB  . ARG D 2 71  ? -34.417 -14.063 27.902  1   25.07  ? 241 ARG D CB  1 
ATOM   7523 C  CG  . ARG D 2 71  ? -35.619 -13.991 26.972  1   26.09  ? 241 ARG D CG  1 
ATOM   7524 C  CD  . ARG D 2 71  ? -36.606 -12.916 27.374  1   27.46  ? 241 ARG D CD  1 
ATOM   7525 N  NE  . ARG D 2 71  ? -36.123 -11.642 26.848  1   28.57  ? 241 ARG D NE  1 
ATOM   7526 C  CZ  . ARG D 2 71  ? -36.241 -10.47  27.461  1   28.94  ? 241 ARG D CZ  1 
ATOM   7527 N  NH1 . ARG D 2 71  ? -37.078 -10.322 28.473  1   28.54  ? 241 ARG D NH1 1 
ATOM   7528 N  NH2 . ARG D 2 71  ? -35.55  -9.442  27.004  1   28.66  ? 241 ARG D NH2 1 
ATOM   7529 N  N   . PHE D 2 72  ? -32.112 -15.4   29.741  1   26.57  ? 242 PHE D N   1 
ATOM   7530 C  CA  . PHE D 2 72  ? -30.753 -15.424 30.263  1   23.31  ? 242 PHE D CA  1 
ATOM   7531 C  C   . PHE D 2 72  ? -30.067 -16.743 29.905  1   25.59  ? 242 PHE D C   1 
ATOM   7532 O  O   . PHE D 2 72  ? -28.929 -16.722 29.418  1   28.98  ? 242 PHE D O   1 
ATOM   7533 C  CB  . PHE D 2 72  ? -30.779 -15.115 31.758  1   20.79  ? 242 PHE D CB  1 
ATOM   7534 C  CG  . PHE D 2 72  ? -29.393 -14.913 32.331  1   21.82  ? 242 PHE D CG  1 
ATOM   7535 C  CD1 . PHE D 2 72  ? -28.794 -13.665 32.311  1   20.8   ? 242 PHE D CD1 1 
ATOM   7536 C  CD2 . PHE D 2 72  ? -28.686 -15.992 32.863  1   21.88  ? 242 PHE D CD2 1 
ATOM   7537 C  CE1 . PHE D 2 72  ? -27.53  -13.507 32.854  1   22.14  ? 242 PHE D CE1 1 
ATOM   7538 C  CE2 . PHE D 2 72  ? -27.416 -15.826 33.378  1   19.89  ? 242 PHE D CE2 1 
ATOM   7539 C  CZ  . PHE D 2 72  ? -26.859 -14.578 33.394  1   21.43  ? 242 PHE D CZ  1 
ATOM   7540 N  N   . LEU D 2 73  ? -30.753 -17.867 30.179  1   24.6   ? 243 LEU D N   1 
ATOM   7541 C  CA  . LEU D 2 73  ? -30.241 -19.206 29.922  1   27.2   ? 243 LEU D CA  1 
ATOM   7542 C  C   . LEU D 2 73  ? -30.201 -19.521 28.42   1   25.79  ? 243 LEU D C   1 
ATOM   7543 O  O   . LEU D 2 73  ? -29.577 -20.513 28.032  1   24.29  ? 243 LEU D O   1 
ATOM   7544 C  CB  . LEU D 2 73  ? -31.104 -20.229 30.668  1   29.5   ? 243 LEU D CB  1 
ATOM   7545 C  CG  . LEU D 2 73  ? -31.114 -20.141 32.199  1   28.58  ? 243 LEU D CG  1 
ATOM   7546 C  CD1 . LEU D 2 73  ? -31.965 -21.251 32.793  1   24.79  ? 243 LEU D CD1 1 
ATOM   7547 C  CD2 . LEU D 2 73  ? -29.687 -20.247 32.693  1   29.15  ? 243 LEU D CD2 1 
ATOM   7548 N  N   . SER D 2 74  ? -30.87  -18.689 27.601  1   25.52  ? 244 SER D N   1 
ATOM   7549 C  CA  . SER D 2 74  ? -30.81  -18.768 26.143  1   28.47  ? 244 SER D CA  1 
ATOM   7550 C  C   . SER D 2 74  ? -29.513 -18.152 25.606  1   25.17  ? 244 SER D C   1 
ATOM   7551 O  O   . SER D 2 74  ? -29.185 -18.319 24.435  1   26.11  ? 244 SER D O   1 
ATOM   7552 C  CB  . SER D 2 74  ? -32.048 -18.157 25.477  1   30.82  ? 244 SER D CB  1 
ATOM   7553 O  OG  . SER D 2 74  ? -33.223 -18.894 25.813  1   37.36  ? 244 SER D OG  1 
ATOM   7554 N  N   . SER D 2 75  ? -28.756 -17.47  26.476  1   25.49  ? 245 SER D N   1 
ATOM   7555 C  CA  . SER D 2 75  ? -27.545 -16.769 26.05   1   27.7   ? 245 SER D CA  1 
ATOM   7556 C  C   . SER D 2 75  ? -26.354 -17.115 26.945  1   25.7   ? 245 SER D C   1 
ATOM   7557 O  O   . SER D 2 75  ? -25.211 -16.878 26.569  1   25.83  ? 245 SER D O   1 
ATOM   7558 C  CB  . SER D 2 75  ? -27.744 -15.26  25.989  1   32.54  ? 245 SER D CB  1 
ATOM   7559 O  OG  . SER D 2 75  ? -28.694 -14.885 24.989  1   45.27  ? 245 SER D OG  1 
ATOM   7560 N  N   . MET D 2 76  ? -26.592 -17.682 28.134  1   23.16  ? 246 MET D N   1 
ATOM   7561 C  CA  . MET D 2 76  ? -25.488 -17.823 29.078  1   23.07  ? 246 MET D CA  1 
ATOM   7562 C  C   . MET D 2 76  ? -25.454 -19.246 29.643  1   23.7   ? 246 MET D C   1 
ATOM   7563 O  O   . MET D 2 76  ? -26.448 -19.774 30.147  1   24.47  ? 246 MET D O   1 
ATOM   7564 C  CB  . MET D 2 76  ? -25.609 -16.8   30.221  1   22.35  ? 246 MET D CB  1 
ATOM   7565 C  CG  . MET D 2 76  ? -25.73  -15.374 29.747  1   23.85  ? 246 MET D CG  1 
ATOM   7566 S  SD  . MET D 2 76  ? -24.135 -14.666 29.297  1   29.53  ? 246 MET D SD  1 
ATOM   7567 C  CE  . MET D 2 76  ? -23.37  -14.494 30.916  1   21.52  ? 246 MET D CE  1 
ATOM   7568 N  N   . SER D 2 77  ? -24.284 -19.865 29.567  1   21.76  ? 247 SER D N   1 
ATOM   7569 C  CA  . SER D 2 77  ? -24.097 -21.169 30.165  1   22.35  ? 247 SER D CA  1 
ATOM   7570 C  C   . SER D 2 77  ? -24.004 -20.989 31.68   1   24.76  ? 247 SER D C   1 
ATOM   7571 O  O   . SER D 2 77  ? -23.245 -20.153 32.171  1   27.64  ? 247 SER D O   1 
ATOM   7572 C  CB  . SER D 2 77  ? -22.877 -21.849 29.588  1   21.91  ? 247 SER D CB  1 
ATOM   7573 O  OG  . SER D 2 77  ? -23.162 -22.32  28.27   1   28.93  ? 247 SER D OG  1 
ATOM   7574 N  N   . VAL D 2 78  ? -24.806 -21.765 32.417  1   23.42  ? 248 VAL D N   1 
ATOM   7575 C  CA  . VAL D 2 78  ? -24.86  -21.64  33.862  1   23.03  ? 248 VAL D CA  1 
ATOM   7576 C  C   . VAL D 2 78  ? -24.629 -23.004 34.499  1   23.21  ? 248 VAL D C   1 
ATOM   7577 O  O   . VAL D 2 78  ? -25.288 -23.97  34.138  1   26.07  ? 248 VAL D O   1 
ATOM   7578 C  CB  . VAL D 2 78  ? -26.186 -20.998 34.324  1   22.1   ? 248 VAL D CB  1 
ATOM   7579 C  CG1 . VAL D 2 78  ? -26.339 -21.016 35.838  1   19.35  ? 248 VAL D CG1 1 
ATOM   7580 C  CG2 . VAL D 2 78  ? -26.326 -19.569 33.794  1   20.28  ? 248 VAL D CG2 1 
ATOM   7581 N  N   . LEU D 2 79  ? -23.7   -23.065 35.461  1   23.18  ? 249 LEU D N   1 
ATOM   7582 C  CA  . LEU D 2 79  ? -23.495 -24.256 36.278  1   22.75  ? 249 LEU D CA  1 
ATOM   7583 C  C   . LEU D 2 79  ? -24.676 -24.453 37.226  1   22.72  ? 249 LEU D C   1 
ATOM   7584 O  O   . LEU D 2 79  ? -25.42  -23.512 37.5    1   22.08  ? 249 LEU D O   1 
ATOM   7585 C  CB  . LEU D 2 79  ? -22.165 -24.185 37.025  1   20.68  ? 249 LEU D CB  1 
ATOM   7586 C  CG  . LEU D 2 79  ? -20.93  -24.365 36.142  1   20.06  ? 249 LEU D CG  1 
ATOM   7587 C  CD1 . LEU D 2 79  ? -19.728 -24.83  36.943  1   21.06  ? 249 LEU D CD1 1 
ATOM   7588 C  CD2 . LEU D 2 79  ? -21.186 -25.275 34.958  1   19.34  ? 249 LEU D CD2 1 
ATOM   7589 N  N   . ARG D 2 80  ? -24.844 -25.684 37.718  1   23.51  ? 250 ARG D N   1 
ATOM   7590 C  CA  . ARG D 2 80  ? -26.034 -26.05  38.478  1   25.25  ? 250 ARG D CA  1 
ATOM   7591 C  C   . ARG D 2 80  ? -26.13  -25.288 39.81   1   27.14  ? 250 ARG D C   1 
ATOM   7592 O  O   . ARG D 2 80  ? -27.247 -24.961 40.239  1   27.21  ? 250 ARG D O   1 
ATOM   7593 C  CB  . ARG D 2 80  ? -26.097 -27.567 38.631  1   25.41  ? 250 ARG D CB  1 
ATOM   7594 C  CG  . ARG D 2 80  ? -27.23  -28.057 39.513  1   29.32  ? 250 ARG D CG  1 
ATOM   7595 C  CD  . ARG D 2 80  ? -26.944 -29.523 39.691  1   34.07  ? 250 ARG D CD  1 
ATOM   7596 N  NE  . ARG D 2 80  ? -25.621 -29.766 40.276  1   36.46  ? 250 ARG D NE  1 
ATOM   7597 C  CZ  . ARG D 2 80  ? -25.052 -30.969 40.349  1   42.7   ? 250 ARG D CZ  1 
ATOM   7598 N  NH1 . ARG D 2 80  ? -25.633 -32.047 39.814  1   43.32  ? 250 ARG D NH1 1 
ATOM   7599 N  NH2 . ARG D 2 80  ? -23.883 -31.092 40.955  1   40.3   ? 250 ARG D NH2 1 
ATOM   7600 N  N   . GLY D 2 81  ? -24.98  -24.973 40.438  1   23.17  ? 251 GLY D N   1 
ATOM   7601 C  CA  . GLY D 2 81  ? -24.982 -24.318 41.735  1   23.53  ? 251 GLY D CA  1 
ATOM   7602 C  C   . GLY D 2 81  ? -25.231 -22.817 41.637  1   26.75  ? 251 GLY D C   1 
ATOM   7603 O  O   . GLY D 2 81  ? -25.236 -22.125 42.654  1   28.38  ? 251 GLY D O   1 
ATOM   7604 N  N   . LYS D 2 82  ? -25.436 -22.324 40.407  1   26.85  ? 252 LYS D N   1 
ATOM   7605 C  CA  . LYS D 2 82  ? -25.567 -20.899 40.16   1   26.01  ? 252 LYS D CA  1 
ATOM   7606 C  C   . LYS D 2 82  ? -26.912 -20.607 39.506  1   28.04  ? 252 LYS D C   1 
ATOM   7607 O  O   . LYS D 2 82  ? -27.232 -19.441 39.264  1   28.68  ? 252 LYS D O   1 
ATOM   7608 C  CB  . LYS D 2 82  ? -24.434 -20.412 39.257  1   24.65  ? 252 LYS D CB  1 
ATOM   7609 C  CG  . LYS D 2 82  ? -23.091 -20.345 39.944  1   25.29  ? 252 LYS D CG  1 
ATOM   7610 C  CD  . LYS D 2 82  ? -23.203 -19.376 41.109  1   26.79  ? 252 LYS D CD  1 
ATOM   7611 C  CE  . LYS D 2 82  ? -21.871 -18.873 41.552  1   27.5   ? 252 LYS D CE  1 
ATOM   7612 N  NZ  . LYS D 2 82  ? -21.101 -20.102 41.761  1   30.28  ? 252 LYS D NZ  1 
ATOM   7613 N  N   . LEU D 2 83  ? -27.675 -21.672 39.221  1   26.96  ? 253 LEU D N   1 
ATOM   7614 C  CA  . LEU D 2 83  ? -28.993 -21.546 38.622  1   27.28  ? 253 LEU D CA  1 
ATOM   7615 C  C   . LEU D 2 83  ? -29.968 -20.841 39.572  1   27.27  ? 253 LEU D C   1 
ATOM   7616 O  O   . LEU D 2 83  ? -30.848 -20.107 39.123  1   26.26  ? 253 LEU D O   1 
ATOM   7617 C  CB  . LEU D 2 83  ? -29.485 -22.939 38.253  1   26.63  ? 253 LEU D CB  1 
ATOM   7618 C  CG  . LEU D 2 83  ? -30.891 -22.988 37.658  1   27.1   ? 253 LEU D CG  1 
ATOM   7619 C  CD1 . LEU D 2 83  ? -30.982 -22.178 36.331  1   24.37  ? 253 LEU D CD1 1 
ATOM   7620 C  CD2 . LEU D 2 83  ? -31.274 -24.453 37.501  1   24.69  ? 253 LEU D CD2 1 
ATOM   7621 N  N   . GLN D 2 84  ? -29.82  -21.049 40.884  1   26.66  ? 254 GLN D N   1 
ATOM   7622 C  CA  . GLN D 2 84  ? -30.672 -20.32  41.818  1   29.62  ? 254 GLN D CA  1 
ATOM   7623 C  C   . GLN D 2 84  ? -30.287 -18.836 41.906  1   27.34  ? 254 GLN D C   1 
ATOM   7624 O  O   . GLN D 2 84  ? -31.14  -17.997 42.188  1   29.24  ? 254 GLN D O   1 
ATOM   7625 C  CB  . GLN D 2 84  ? -30.731 -20.984 43.192  1   25.63  ? 254 GLN D CB  1 
ATOM   7626 C  CG  . GLN D 2 84  ? -31.924 -20.534 44.022  1   24.49  ? 254 GLN D CG  1 
ATOM   7627 C  CD  . GLN D 2 84  ? -32.005 -21.279 45.332  1   24.79  ? 254 GLN D CD  1 
ATOM   7628 O  OE1 . GLN D 2 84  ? -32.954 -21.112 46.103  1   28.83  ? 254 GLN D OE1 1 
ATOM   7629 N  NE2 . GLN D 2 84  ? -31.009 -22.108 45.602  1   21.76  ? 254 GLN D NE2 1 
ATOM   7630 N  N   . LEU D 2 85  ? -29.011 -18.516 41.654  1   22.96  ? 255 LEU D N   1 
ATOM   7631 C  CA  . LEU D 2 85  ? -28.57  -17.138 41.735  1   21.46  ? 255 LEU D CA  1 
ATOM   7632 C  C   . LEU D 2 85  ? -29.226 -16.348 40.61   1   21.65  ? 255 LEU D C   1 
ATOM   7633 O  O   . LEU D 2 85  ? -29.676 -15.234 40.846  1   21.39  ? 255 LEU D O   1 
ATOM   7634 C  CB  . LEU D 2 85  ? -27.047 -17.061 41.755  1   19.76  ? 255 LEU D CB  1 
ATOM   7635 C  CG  . LEU D 2 85  ? -26.437 -15.677 41.962  1   20.07  ? 255 LEU D CG  1 
ATOM   7636 C  CD1 . LEU D 2 85  ? -26.907 -14.979 43.244  1   18.61  ? 255 LEU D CD1 1 
ATOM   7637 C  CD2 . LEU D 2 85  ? -24.921 -15.793 41.903  1   19.1   ? 255 LEU D CD2 1 
ATOM   7638 N  N   . VAL D 2 86  ? -29.386 -16.986 39.439  1   23.97  ? 256 VAL D N   1 
ATOM   7639 C  CA  . VAL D 2 86  ? -30.03  -16.406 38.271  1   21.77  ? 256 VAL D CA  1 
ATOM   7640 C  C   . VAL D 2 86  ? -31.511 -16.157 38.563  1   22.52  ? 256 VAL D C   1 
ATOM   7641 O  O   . VAL D 2 86  ? -32.035 -15.086 38.226  1   22.61  ? 256 VAL D O   1 
ATOM   7642 C  CB  . VAL D 2 86  ? -29.824 -17.211 36.973  1   20.83  ? 256 VAL D CB  1 
ATOM   7643 C  CG1 . VAL D 2 86  ? -30.581 -16.546 35.825  1   18.7   ? 256 VAL D CG1 1 
ATOM   7644 C  CG2 . VAL D 2 86  ? -28.34  -17.343 36.618  1   19.14  ? 256 VAL D CG2 1 
ATOM   7645 N  N   . GLY D 2 87  ? -32.182 -17.146 39.18   1   21.97  ? 257 GLY D N   1 
ATOM   7646 C  CA  . GLY D 2 87  ? -33.599 -17.053 39.515  1   22.27  ? 257 GLY D CA  1 
ATOM   7647 C  C   . GLY D 2 87  ? -33.865 -16.014 40.609  1   25.4   ? 257 GLY D C   1 
ATOM   7648 O  O   . GLY D 2 87  ? -34.826 -15.255 40.526  1   27.57  ? 257 GLY D O   1 
ATOM   7649 N  N   . THR D 2 88  ? -33.009 -15.979 41.644  1   25.96  ? 258 THR D N   1 
ATOM   7650 C  CA  . THR D 2 88  ? -33.075 -14.976 42.698  1   25.61  ? 258 THR D CA  1 
ATOM   7651 C  C   . THR D 2 88  ? -32.962 -13.584 42.064  1   26.33  ? 258 THR D C   1 
ATOM   7652 O  O   . THR D 2 88  ? -33.746 -12.7   42.413  1   26.53  ? 258 THR D O   1 
ATOM   7653 C  CB  . THR D 2 88  ? -32.026 -15.238 43.78   1   24.31  ? 258 THR D CB  1 
ATOM   7654 O  OG1 . THR D 2 88  ? -32.104 -16.632 44.071  1   27.96  ? 258 THR D OG1 1 
ATOM   7655 C  CG2 . THR D 2 88  ? -32.292 -14.457 45.052  1   24.44  ? 258 THR D CG2 1 
ATOM   7656 N  N   . ALA D 2 89  ? -32.039 -13.414 41.095  1   24.44  ? 259 ALA D N   1 
ATOM   7657 C  CA  . ALA D 2 89  ? -31.779 -12.105 40.504  1   24.58  ? 259 ALA D CA  1 
ATOM   7658 C  C   . ALA D 2 89  ? -32.927 -11.691 39.586  1   25.14  ? 259 ALA D C   1 
ATOM   7659 O  O   . ALA D 2 89  ? -33.326 -10.529 39.602  1   28.62  ? 259 ALA D O   1 
ATOM   7660 C  CB  . ALA D 2 89  ? -30.42  -12.018 39.84   1   19.92  ? 259 ALA D CB  1 
ATOM   7661 N  N   . ALA D 2 90  ? -33.516 -12.639 38.871  1   23.21  ? 260 ALA D N   1 
ATOM   7662 C  CA  . ALA D 2 90  ? -34.649 -12.338 37.967  1   22.9   ? 260 ALA D CA  1 
ATOM   7663 C  C   . ALA D 2 90  ? -35.9   -11.959 38.758  1   25.4   ? 260 ALA D C   1 
ATOM   7664 O  O   . ALA D 2 90  ? -36.637 -11.074 38.317  1   30.33  ? 260 ALA D O   1 
ATOM   7665 C  CB  . ALA D 2 90  ? -34.902 -13.524 37.088  1   19.55  ? 260 ALA D CB  1 
ATOM   7666 N  N   . MET D 2 91  ? -36.123 -12.614 39.89   1   24.51  ? 261 MET D N   1 
ATOM   7667 C  CA  . MET D 2 91  ? -37.296 -12.314 40.742  1   26.3   ? 261 MET D CA  1 
ATOM   7668 C  C   . MET D 2 91  ? -37.139 -10.907 41.332  1   28.77  ? 261 MET D C   1 
ATOM   7669 O  O   . MET D 2 91  ? -38.137 -10.178 41.358  1   29.29  ? 261 MET D O   1 
ATOM   7670 C  CB  . MET D 2 91  ? -37.453 -13.376 41.84   1   27.11  ? 261 MET D CB  1 
ATOM   7671 C  CG  . MET D 2 91  ? -38.828 -13.44  42.463  1   29.19  ? 261 MET D CG  1 
ATOM   7672 S  SD  . MET D 2 91  ? -40.123 -13.736 41.247  1   37.11  ? 261 MET D SD  1 
ATOM   7673 C  CE  . MET D 2 91  ? -41.201 -14.853 42.148  1   31.77  ? 261 MET D CE  1 
ATOM   7674 N  N   . LEU D 2 92  ? -35.935 -10.547 41.77   1   24.69  ? 262 LEU D N   1 
ATOM   7675 C  CA  . LEU D 2 92  ? -35.685 -9.186  42.294  1   24.22  ? 262 LEU D CA  1 
ATOM   7676 C  C   . LEU D 2 92  ? -35.949 -8.158  41.188  1   24.08  ? 262 LEU D C   1 
ATOM   7677 O  O   . LEU D 2 92  ? -36.586 -7.148  41.466  1   24.13  ? 262 LEU D O   1 
ATOM   7678 C  CB  . LEU D 2 92  ? -34.254 -9.141  42.818  1   22.19  ? 262 LEU D CB  1 
ATOM   7679 C  CG  . LEU D 2 92  ? -33.681 -7.762  43.147  1   19.85  ? 262 LEU D CG  1 
ATOM   7680 C  CD1 . LEU D 2 92  ? -34.382 -7.168  44.348  1   20.04  ? 262 LEU D CD1 1 
ATOM   7681 C  CD2 . LEU D 2 92  ? -32.197 -7.894  43.41   1   18.59  ? 262 LEU D CD2 1 
ATOM   7682 N  N   . LEU D 2 93  ? -35.496 -8.438  39.977  1   24.17  ? 263 LEU D N   1 
ATOM   7683 C  CA  . LEU D 2 93  ? -35.672 -7.5    38.847  1   24.86  ? 263 LEU D CA  1 
ATOM   7684 C  C   . LEU D 2 93  ? -37.148 -7.449  38.455  1   25.41  ? 263 LEU D C   1 
ATOM   7685 O  O   . LEU D 2 93  ? -37.621 -6.364  38.115  1   26.38  ? 263 LEU D O   1 
ATOM   7686 C  CB  . LEU D 2 93  ? -34.781 -7.955  37.697  1   25.31  ? 263 LEU D CB  1 
ATOM   7687 C  CG  . LEU D 2 93  ? -33.312 -7.55   37.787  1   27.19  ? 263 LEU D CG  1 
ATOM   7688 C  CD1 . LEU D 2 93  ? -32.535 -8.218  36.676  1   26.29  ? 263 LEU D CD1 1 
ATOM   7689 C  CD2 . LEU D 2 93  ? -33.242 -6.049  37.661  1   26.51  ? 263 LEU D CD2 1 
ATOM   7690 N  N   . ALA D 2 94  ? -37.833 -8.587  38.507  1   22.46  ? 264 ALA D N   1 
ATOM   7691 C  CA  . ALA D 2 94  ? -39.249 -8.588  38.198  1   23.65  ? 264 ALA D CA  1 
ATOM   7692 C  C   . ALA D 2 94  ? -40.048 -7.857  39.281  1   26.67  ? 264 ALA D C   1 
ATOM   7693 O  O   . ALA D 2 94  ? -41.042 -7.202  38.977  1   28.35  ? 264 ALA D O   1 
ATOM   7694 C  CB  . ALA D 2 94  ? -39.734 -9.998  38.028  1   21.9   ? 264 ALA D CB  1 
ATOM   7695 N  N   . SER D 2 95  ? -39.664 -8.027  40.553  1   26.24  ? 265 SER D N   1 
ATOM   7696 C  CA  . SER D 2 95  ? -40.288 -7.314  41.66   1   26.37  ? 265 SER D CA  1 
ATOM   7697 C  C   . SER D 2 95  ? -40.041 -5.807  41.529  1   25.76  ? 265 SER D C   1 
ATOM   7698 O  O   . SER D 2 95  ? -40.953 -4.992  41.709  1   29.24  ? 265 SER D O   1 
ATOM   7699 C  CB  . SER D 2 95  ? -39.786 -7.841  42.977  1   26.89  ? 265 SER D CB  1 
ATOM   7700 O  OG  . SER D 2 95  ? -39.979 -9.241  43.028  1   31.11  ? 265 SER D OG  1 
ATOM   7701 N  N   . LYS D 2 96  ? -38.814 -5.432  41.159  1   22.69  ? 266 LYS D N   1 
ATOM   7702 C  CA  . LYS D 2 96  ? -38.468 -4.03   40.986  1   21.46  ? 266 LYS D CA  1 
ATOM   7703 C  C   . LYS D 2 96  ? -39.258 -3.429  39.832  1   21.14  ? 266 LYS D C   1 
ATOM   7704 O  O   . LYS D 2 96  ? -39.645 -2.27   39.943  1   23.42  ? 266 LYS D O   1 
ATOM   7705 C  CB  . LYS D 2 96  ? -36.96  -3.801  40.82   1   20.82  ? 266 LYS D CB  1 
ATOM   7706 C  CG  . LYS D 2 96  ? -36.125 -3.946  42.096  1   18.2   ? 266 LYS D CG  1 
ATOM   7707 C  CD  . LYS D 2 96  ? -34.681 -3.576  41.831  1   16.9   ? 266 LYS D CD  1 
ATOM   7708 C  CE  . LYS D 2 96  ? -33.786 -3.67   43.032  1   15.51  ? 266 LYS D CE  1 
ATOM   7709 N  NZ  . LYS D 2 96  ? -32.428 -3.262  42.659  1   13.3   ? 266 LYS D NZ  1 
ATOM   7710 N  N   . PHE D 2 97  ? -39.505 -4.21   38.762  1   20.26  ? 267 PHE D N   1 
ATOM   7711 C  CA  . PHE D 2 97  ? -40.212 -3.751  37.575  1   19.69  ? 267 PHE D CA  1 
ATOM   7712 C  C   . PHE D 2 97  ? -41.7   -3.584  37.878  1   21.59  ? 267 PHE D C   1 
ATOM   7713 O  O   . PHE D 2 97  ? -42.291 -2.558  37.535  1   20.28  ? 267 PHE D O   1 
ATOM   7714 C  CB  . PHE D 2 97  ? -39.971 -4.649  36.356  1   20.55  ? 267 PHE D CB  1 
ATOM   7715 C  CG  . PHE D 2 97  ? -40.615 -4.167  35.063  1   21.55  ? 267 PHE D CG  1 
ATOM   7716 C  CD1 . PHE D 2 97  ? -41.901 -4.556  34.725  1   20.92  ? 267 PHE D CD1 1 
ATOM   7717 C  CD2 . PHE D 2 97  ? -39.958 -3.291  34.198  1   24     ? 267 PHE D CD2 1 
ATOM   7718 C  CE1 . PHE D 2 97  ? -42.502 -4.11   33.554  1   23.64  ? 267 PHE D CE1 1 
ATOM   7719 C  CE2 . PHE D 2 97  ? -40.562 -2.847  33.014  1   24.51  ? 267 PHE D CE2 1 
ATOM   7720 C  CZ  . PHE D 2 97  ? -41.84  -3.249  32.694  1   23.32  ? 267 PHE D CZ  1 
ATOM   7721 N  N   . GLU D 2 98  ? -42.291 -4.596  38.534  1   24.47  ? 268 GLU D N   1 
ATOM   7722 C  CA  . GLU D 2 98  ? -43.734 -4.766  38.575  1   24.81  ? 268 GLU D CA  1 
ATOM   7723 C  C   . GLU D 2 98  ? -44.365 -4.292  39.885  1   23.84  ? 268 GLU D C   1 
ATOM   7724 O  O   . GLU D 2 98  ? -45.492 -3.81   39.856  1   24.88  ? 268 GLU D O   1 
ATOM   7725 C  CB  . GLU D 2 98  ? -44.125 -6.22   38.323  1   22.53  ? 268 GLU D CB  1 
ATOM   7726 C  CG  . GLU D 2 98  ? -45.606 -6.351  37.977  1   24.23  ? 268 GLU D CG  1 
ATOM   7727 C  CD  . GLU D 2 98  ? -46.001 -5.634  36.682  1   27.15  ? 268 GLU D CD  1 
ATOM   7728 O  OE1 . GLU D 2 98  ? -45.107 -5.402  35.829  1   25.16  ? 268 GLU D OE1 1 
ATOM   7729 O  OE2 . GLU D 2 98  ? -47.193 -5.254  36.536  1   25.79  ? 268 GLU D OE2 1 
ATOM   7730 N  N   . GLU D 2 99  ? -43.672 -4.479  41.015  1   24.1   ? 269 GLU D N   1 
ATOM   7731 C  CA  . GLU D 2 99  ? -44.301 -4.408  42.331  1   23.34  ? 269 GLU D CA  1 
ATOM   7732 C  C   . GLU D 2 99  ? -44.343 -2.968  42.823  1   23.99  ? 269 GLU D C   1 
ATOM   7733 O  O   . GLU D 2 99  ? -43.354 -2.247  42.731  1   26.98  ? 269 GLU D O   1 
ATOM   7734 C  CB  . GLU D 2 99  ? -43.544 -5.272  43.347  1   22.98  ? 269 GLU D CB  1 
ATOM   7735 C  CG  . GLU D 2 99  ? -43.687 -6.773  43.099  1   24.45  ? 269 GLU D CG  1 
ATOM   7736 C  CD  . GLU D 2 99  ? -45.083 -7.343  43.326  1   26.96  ? 269 GLU D CD  1 
ATOM   7737 O  OE1 . GLU D 2 99  ? -45.848 -6.803  44.172  1   28.01  ? 269 GLU D OE1 1 
ATOM   7738 O  OE2 . GLU D 2 99  ? -45.426 -8.325  42.623  1   24.52  ? 269 GLU D OE2 1 
ATOM   7739 N  N   . ILE D 2 100 ? -45.472 -2.569  43.408  1   24     ? 270 ILE D N   1 
ATOM   7740 C  CA  . ILE D 2 100 ? -45.533 -1.298  44.111  1   24.31  ? 270 ILE D CA  1 
ATOM   7741 C  C   . ILE D 2 100 ? -44.458 -1.26   45.204  1   26.31  ? 270 ILE D C   1 
ATOM   7742 O  O   . ILE D 2 100 ? -43.643 -0.338  45.256  1   27.23  ? 270 ILE D O   1 
ATOM   7743 C  CB  . ILE D 2 100 ? -46.937 -1.058  44.69   1   24.82  ? 270 ILE D CB  1 
ATOM   7744 C  CG1 . ILE D 2 100 ? -48.024 -0.98   43.608  1   23.88  ? 270 ILE D CG1 1 
ATOM   7745 C  CG2 . ILE D 2 100 ? -46.957 0.19    45.575  1   23.1   ? 270 ILE D CG2 1 
ATOM   7746 C  CD1 . ILE D 2 100 ? -49.428 -0.822  44.184  1   21.18  ? 270 ILE D CD1 1 
ATOM   7747 N  N   . TYR D 2 101 ? -44.447 -2.287  46.063  1   28.45  ? 271 TYR D N   1 
ATOM   7748 C  CA  . TYR D 2 101 ? -43.539 -2.372  47.199  1   28.31  ? 271 TYR D CA  1 
ATOM   7749 C  C   . TYR D 2 101 ? -42.739 -3.665  47.074  1   28.75  ? 271 TYR D C   1 
ATOM   7750 O  O   . TYR D 2 101 ? -43.048 -4.65   47.749  1   30.53  ? 271 TYR D O   1 
ATOM   7751 C  CB  . TYR D 2 101 ? -44.3   -2.44   48.53   1   25.43  ? 271 TYR D CB  1 
ATOM   7752 C  CG  . TYR D 2 101 ? -45.257 -1.291  48.775  1   25.35  ? 271 TYR D CG  1 
ATOM   7753 C  CD1 . TYR D 2 101 ? -44.803 -0.075  49.272  1   26.29  ? 271 TYR D CD1 1 
ATOM   7754 C  CD2 . TYR D 2 101 ? -46.618 -1.428  48.507  1   27.2   ? 271 TYR D CD2 1 
ATOM   7755 C  CE1 . TYR D 2 101 ? -45.68  0.979   49.495  1   29.28  ? 271 TYR D CE1 1 
ATOM   7756 C  CE2 . TYR D 2 101 ? -47.508 -0.388  48.74   1   29.31  ? 271 TYR D CE2 1 
ATOM   7757 C  CZ  . TYR D 2 101 ? -47.036 0.825   49.219  1   32.61  ? 271 TYR D CZ  1 
ATOM   7758 O  OH  . TYR D 2 101 ? -47.937 1.849   49.406  1   41.32  ? 271 TYR D OH  1 
ATOM   7759 N  N   . PRO D 2 102 ? -41.694 -3.724  46.211  1   28.72  ? 272 PRO D N   1 
ATOM   7760 C  CA  . PRO D 2 102 ? -40.899 -4.953  46.074  1   25.77  ? 272 PRO D CA  1 
ATOM   7761 C  C   . PRO D 2 102 ? -40.266 -5.314  47.42   1   25.84  ? 272 PRO D C   1 
ATOM   7762 O  O   . PRO D 2 102 ? -40.046 -4.443  48.257  1   28.06  ? 272 PRO D O   1 
ATOM   7763 C  CB  . PRO D 2 102 ? -39.836 -4.556  45.062  1   22.91  ? 272 PRO D CB  1 
ATOM   7764 C  CG  . PRO D 2 102 ? -39.766 -3.061  45.168  1   24.05  ? 272 PRO D CG  1 
ATOM   7765 C  CD  . PRO D 2 102 ? -41.19  -2.613  45.388  1   23.35  ? 272 PRO D CD  1 
ATOM   7766 N  N   . PRO D 2 103 ? -39.942 -6.6    47.694  1   24.59  ? 273 PRO D N   1 
ATOM   7767 C  CA  . PRO D 2 103 ? -39.169 -6.928  48.885  1   23.08  ? 273 PRO D CA  1 
ATOM   7768 C  C   . PRO D 2 103 ? -37.79  -6.318  48.667  1   27.12  ? 273 PRO D C   1 
ATOM   7769 O  O   . PRO D 2 103 ? -37.351 -6.099  47.536  1   28.55  ? 273 PRO D O   1 
ATOM   7770 C  CB  . PRO D 2 103 ? -39.119 -8.452  48.898  1   20.08  ? 273 PRO D CB  1 
ATOM   7771 C  CG  . PRO D 2 103 ? -40.179 -8.88   47.911  1   20.33  ? 273 PRO D CG  1 
ATOM   7772 C  CD  . PRO D 2 103 ? -40.289 -7.783  46.89   1   21.55  ? 273 PRO D CD  1 
ATOM   7773 N  N   . GLU D 2 104 ? -37.083 -6.103  49.772  1   29.85  ? 274 GLU D N   1 
ATOM   7774 C  CA  . GLU D 2 104 ? -35.722 -5.628  49.673  1   28.44  ? 274 GLU D CA  1 
ATOM   7775 C  C   . GLU D 2 104 ? -34.81  -6.773  49.31   1   24.85  ? 274 GLU D C   1 
ATOM   7776 O  O   . GLU D 2 104 ? -35.173 -7.929  49.411  1   23.79  ? 274 GLU D O   1 
ATOM   7777 C  CB  . GLU D 2 104 ? -35.332 -4.977  50.992  1   33.85  ? 274 GLU D CB  1 
ATOM   7778 C  CG  . GLU D 2 104 ? -35.887 -3.56   51.048  1   42.89  ? 274 GLU D CG  1 
ATOM   7779 C  CD  . GLU D 2 104 ? -35.914 -3.125  52.483  1   50.88  ? 274 GLU D CD  1 
ATOM   7780 O  OE1 . GLU D 2 104 ? -35.714 -1.912  52.678  1   61.46  ? 274 GLU D OE1 1 
ATOM   7781 O  OE2 . GLU D 2 104 ? -36.086 -4.001  53.369  1   51.2   ? 274 GLU D OE2 1 
ATOM   7782 N  N   . VAL D 2 105 ? -33.615 -6.402  48.886  1   24.28  ? 275 VAL D N   1 
ATOM   7783 C  CA  . VAL D 2 105 ? -32.655 -7.384  48.44   1   25.24  ? 275 VAL D CA  1 
ATOM   7784 C  C   . VAL D 2 105 ? -32.379 -8.402  49.553  1   24.77  ? 275 VAL D C   1 
ATOM   7785 O  O   . VAL D 2 105 ? -32.217 -9.59   49.282  1   24.6   ? 275 VAL D O   1 
ATOM   7786 C  CB  . VAL D 2 105 ? -31.393 -6.627  47.986  1   23.2   ? 275 VAL D CB  1 
ATOM   7787 C  CG1 . VAL D 2 105 ? -30.271 -7.614  47.735  1   22.47  ? 275 VAL D CG1 1 
ATOM   7788 C  CG2 . VAL D 2 105 ? -31.666 -5.777  46.744  1   22.33  ? 275 VAL D CG2 1 
ATOM   7789 N  N   . ALA D 2 106 ? -32.311 -7.933  50.803  1   23.89  ? 276 ALA D N   1 
ATOM   7790 C  CA  . ALA D 2 106 ? -31.977 -8.805  51.915  1   24.39  ? 276 ALA D CA  1 
ATOM   7791 C  C   . ALA D 2 106 ? -32.955 -9.979  51.987  1   26.45  ? 276 ALA D C   1 
ATOM   7792 O  O   . ALA D 2 106 ? -32.57  -11.078 52.379  1   29.06  ? 276 ALA D O   1 
ATOM   7793 C  CB  . ALA D 2 106 ? -31.942 -8.023  53.204  1   20.74  ? 276 ALA D CB  1 
ATOM   7794 N  N   . GLU D 2 107 ? -34.217 -9.738  51.609  1   27.59  ? 277 GLU D N   1 
ATOM   7795 C  CA  . GLU D 2 107 ? -35.257 -10.75  51.708  1   29.61  ? 277 GLU D CA  1 
ATOM   7796 C  C   . GLU D 2 107 ? -34.99  -11.832 50.665  1   29.77  ? 277 GLU D C   1 
ATOM   7797 O  O   . GLU D 2 107 ? -35.289 -13     50.903  1   34.12  ? 277 GLU D O   1 
ATOM   7798 C  CB  . GLU D 2 107 ? -36.656 -10.137 51.654  1   30.8   ? 277 GLU D CB  1 
ATOM   7799 C  CG  . GLU D 2 107 ? -37.016 -9.309  52.891  1   40.35  ? 277 GLU D CG  1 
ATOM   7800 C  CD  . GLU D 2 107 ? -38.276 -8.435  52.76   1   56.12  ? 277 GLU D CD  1 
ATOM   7801 O  OE1 . GLU D 2 107 ? -39.384 -8.956  53.051  1   64.57  ? 277 GLU D OE1 1 
ATOM   7802 O  OE2 . GLU D 2 107 ? -38.194 -7.243  52.331  1   57.06  ? 277 GLU D OE2 1 
ATOM   7803 N  N   . PHE D 2 108 ? -34.383 -11.428 49.54   1   26.6   ? 278 PHE D N   1 
ATOM   7804 C  CA  . PHE D 2 108 ? -34.036 -12.307 48.436  1   26.59  ? 278 PHE D CA  1 
ATOM   7805 C  C   . PHE D 2 108 ? -32.803 -13.135 48.785  1   31.09  ? 278 PHE D C   1 
ATOM   7806 O  O   . PHE D 2 108 ? -32.645 -14.264 48.312  1   36.58  ? 278 PHE D O   1 
ATOM   7807 C  CB  . PHE D 2 108 ? -33.735 -11.512 47.162  1   25.53  ? 278 PHE D CB  1 
ATOM   7808 C  CG  . PHE D 2 108 ? -35.02  -11.037 46.525  1   26.72  ? 278 PHE D CG  1 
ATOM   7809 C  CD1 . PHE D 2 108 ? -35.785 -11.919 45.76   1   28.34  ? 278 PHE D CD1 1 
ATOM   7810 C  CD2 . PHE D 2 108 ? -35.495 -9.745  46.75   1   25.93  ? 278 PHE D CD2 1 
ATOM   7811 C  CE1 . PHE D 2 108 ? -36.995 -11.509 45.207  1   29.65  ? 278 PHE D CE1 1 
ATOM   7812 C  CE2 . PHE D 2 108 ? -36.707 -9.341  46.193  1   28.1   ? 278 PHE D CE2 1 
ATOM   7813 C  CZ  . PHE D 2 108 ? -37.444 -10.215 45.406  1   29.23  ? 278 PHE D CZ  1 
ATOM   7814 N  N   . VAL D 2 109 ? -31.899 -12.539 49.565  1   28.74  ? 279 VAL D N   1 
ATOM   7815 C  CA  . VAL D 2 109 ? -30.761 -13.296 50.053  1   30.28  ? 279 VAL D CA  1 
ATOM   7816 C  C   . VAL D 2 109 ? -31.229 -14.287 51.117  1   29.13  ? 279 VAL D C   1 
ATOM   7817 O  O   . VAL D 2 109 ? -30.608 -15.325 51.309  1   32.36  ? 279 VAL D O   1 
ATOM   7818 C  CB  . VAL D 2 109 ? -29.655 -12.365 50.595  1   27.51  ? 279 VAL D CB  1 
ATOM   7819 C  CG1 . VAL D 2 109 ? -28.528 -13.133 51.274  1   22.65  ? 279 VAL D CG1 1 
ATOM   7820 C  CG2 . VAL D 2 109 ? -29.11  -11.472 49.5    1   24.8   ? 279 VAL D CG2 1 
ATOM   7821 N  N   . TYR D 2 110 ? -32.297 -13.941 51.835  1   28.53  ? 280 TYR D N   1 
ATOM   7822 C  CA  . TYR D 2 110 ? -32.732 -14.775 52.938  1   29.37  ? 280 TYR D CA  1 
ATOM   7823 C  C   . TYR D 2 110 ? -33.384 -16.05  52.398  1   28.37  ? 280 TYR D C   1 
ATOM   7824 O  O   . TYR D 2 110 ? -33.161 -17.106 52.958  1   27.99  ? 280 TYR D O   1 
ATOM   7825 C  CB  . TYR D 2 110 ? -33.525 -13.926 53.932  1   33.29  ? 280 TYR D CB  1 
ATOM   7826 C  CG  . TYR D 2 110 ? -34.174 -14.717 55.06   1   44.85  ? 280 TYR D CG  1 
ATOM   7827 C  CD1 . TYR D 2 110 ? -35.428 -15.309 54.888  1   47.37  ? 280 TYR D CD1 1 
ATOM   7828 C  CD2 . TYR D 2 110 ? -33.549 -14.861 56.3    1   50.73  ? 280 TYR D CD2 1 
ATOM   7829 C  CE1 . TYR D 2 110 ? -36.035 -16.028 55.906  1   48.61  ? 280 TYR D CE1 1 
ATOM   7830 C  CE2 . TYR D 2 110 ? -34.155 -15.566 57.331  1   51.64  ? 280 TYR D CE2 1 
ATOM   7831 C  CZ  . TYR D 2 110 ? -35.395 -16.153 57.128  1   52.46  ? 280 TYR D CZ  1 
ATOM   7832 O  OH  . TYR D 2 110 ? -36.017 -16.847 58.123  1   56.75  ? 280 TYR D OH  1 
ATOM   7833 N  N   . ILE D 2 111 ? -34.13  -15.968 51.286  1   30.28  ? 281 ILE D N   1 
ATOM   7834 C  CA  . ILE D 2 111 ? -34.855 -17.112 50.74   1   34.29  ? 281 ILE D CA  1 
ATOM   7835 C  C   . ILE D 2 111 ? -33.958 -18.127 50.022  1   34.99  ? 281 ILE D C   1 
ATOM   7836 O  O   . ILE D 2 111 ? -34.424 -19.227 49.737  1   35.58  ? 281 ILE D O   1 
ATOM   7837 C  CB  . ILE D 2 111 ? -35.968 -16.676 49.774  1   36.22  ? 281 ILE D CB  1 
ATOM   7838 C  CG1 . ILE D 2 111 ? -35.46  -15.658 48.796  1   33.93  ? 281 ILE D CG1 1 
ATOM   7839 C  CG2 . ILE D 2 111 ? -37.215 -16.195 50.507  1   38.77  ? 281 ILE D CG2 1 
ATOM   7840 C  CD1 . ILE D 2 111 ? -36.231 -15.639 47.49   1   37.61  ? 281 ILE D CD1 1 
ATOM   7841 N  N   . THR D 2 112 ? -32.732 -17.75  49.633  1   34.99  ? 282 THR D N   1 
ATOM   7842 C  CA  . THR D 2 112 ? -31.78  -18.708 49.083  1   34.83  ? 282 THR D CA  1 
ATOM   7843 C  C   . THR D 2 112 ? -31.067 -19.433 50.219  1   40.49  ? 282 THR D C   1 
ATOM   7844 O  O   . THR D 2 112 ? -30.108 -20.156 49.958  1   42.36  ? 282 THR D O   1 
ATOM   7845 C  CB  . THR D 2 112 ? -30.739 -18.064 48.164  1   32.51  ? 282 THR D CB  1 
ATOM   7846 O  OG1 . THR D 2 112 ? -29.917 -17.232 48.978  1   34.16  ? 282 THR D OG1 1 
ATOM   7847 C  CG2 . THR D 2 112 ? -31.335 -17.345 46.97   1   26.78  ? 282 THR D CG2 1 
ATOM   7848 N  N   . ASP D 2 113 ? -31.526 -19.195 51.462  1   51.42  ? 283 ASP D N   1 
ATOM   7849 C  CA  . ASP D 2 113 ? -31.004 -19.781 52.696  1   56.61  ? 283 ASP D CA  1 
ATOM   7850 C  C   . ASP D 2 113 ? -29.509 -19.515 52.859  1   54     ? 283 ASP D C   1 
ATOM   7851 O  O   . ASP D 2 113 ? -28.774 -20.371 53.343  1   45.92  ? 283 ASP D O   1 
ATOM   7852 C  CB  . ASP D 2 113 ? -31.347 -21.256 52.829  1   68.2   ? 283 ASP D CB  1 
ATOM   7853 C  CG  . ASP D 2 113 ? -32.776 -21.548 53.255  1   85.43  ? 283 ASP D CG  1 
ATOM   7854 O  OD1 . ASP D 2 113 ? -33.663 -21.609 52.37   1   95.76  ? 283 ASP D OD1 1 
ATOM   7855 O  OD2 . ASP D 2 113 ? -32.992 -21.68  54.476  1   86.84  ? 283 ASP D OD2 1 
ATOM   7856 N  N   . ASP D 2 114 ? -29.064 -18.326 52.439  1   62.25  ? 284 ASP D N   1 
ATOM   7857 C  CA  . ASP D 2 114 ? -27.653 -17.963 52.515  1   69.21  ? 284 ASP D CA  1 
ATOM   7858 C  C   . ASP D 2 114 ? -26.77  -18.938 51.721  1   61.78  ? 284 ASP D C   1 
ATOM   7859 O  O   . ASP D 2 114 ? -25.616 -19.173 52.073  1   57.61  ? 284 ASP D O   1 
ATOM   7860 C  CB  . ASP D 2 114 ? -27.209 -17.732 53.956  1   77.88  ? 284 ASP D CB  1 
ATOM   7861 C  CG  . ASP D 2 114 ? -28.144 -16.873 54.801  1   78.8   ? 284 ASP D CG  1 
ATOM   7862 O  OD1 . ASP D 2 114 ? -28.537 -15.784 54.318  1   74.44  ? 284 ASP D OD1 1 
ATOM   7863 O  OD2 . ASP D 2 114 ? -28.458 -17.288 55.943  1   76.05  ? 284 ASP D OD2 1 
ATOM   7864 N  N   . THR D 2 115 ? -27.299 -19.48  50.617  1   55.09  ? 285 THR D N   1 
ATOM   7865 C  CA  . THR D 2 115 ? -26.454 -20.133 49.629  1   52.18  ? 285 THR D CA  1 
ATOM   7866 C  C   . THR D 2 115 ? -25.507 -19.083 49.031  1   47.7   ? 285 THR D C   1 
ATOM   7867 O  O   . THR D 2 115 ? -24.348 -19.379 48.744  1   48.65  ? 285 THR D O   1 
ATOM   7868 C  CB  . THR D 2 115 ? -27.307 -20.816 48.548  1   55.2   ? 285 THR D CB  1 
ATOM   7869 O  OG1 . THR D 2 115 ? -28.308 -21.665 49.102  1   50.64  ? 285 THR D OG1 1 
ATOM   7870 C  CG2 . THR D 2 115 ? -26.486 -21.659 47.588  1   50.81  ? 285 THR D CG2 1 
ATOM   7871 N  N   . TYR D 2 116 ? -26.026 -17.868 48.796  1   37.51  ? 286 TYR D N   1 
ATOM   7872 C  CA  . TYR D 2 116 ? -25.269 -16.807 48.154  1   33.12  ? 286 TYR D CA  1 
ATOM   7873 C  C   . TYR D 2 116 ? -25.228 -15.569 49.049  1   32.99  ? 286 TYR D C   1 
ATOM   7874 O  O   . TYR D 2 116 ? -26.137 -15.295 49.831  1   30.01  ? 286 TYR D O   1 
ATOM   7875 C  CB  . TYR D 2 116 ? -25.857 -16.415 46.793  1   31.36  ? 286 TYR D CB  1 
ATOM   7876 C  CG  . TYR D 2 116 ? -26.233 -17.591 45.901  1   32.25  ? 286 TYR D CG  1 
ATOM   7877 C  CD1 . TYR D 2 116 ? -25.257 -18.385 45.297  1   31.96  ? 286 TYR D CD1 1 
ATOM   7878 C  CD2 . TYR D 2 116 ? -27.566 -17.93  45.693  1   29.29  ? 286 TYR D CD2 1 
ATOM   7879 C  CE1 . TYR D 2 116 ? -25.597 -19.467 44.498  1   29.55  ? 286 TYR D CE1 1 
ATOM   7880 C  CE2 . TYR D 2 116 ? -27.915 -19.006 44.897  1   27.17  ? 286 TYR D CE2 1 
ATOM   7881 C  CZ  . TYR D 2 116 ? -26.932 -19.774 44.304  1   27.15  ? 286 TYR D CZ  1 
ATOM   7882 O  OH  . TYR D 2 116 ? -27.307 -20.822 43.529  1   28.06  ? 286 TYR D OH  1 
ATOM   7883 N  N   . THR D 2 117 ? -24.152 -14.796 48.894  1   30.16  ? 287 THR D N   1 
ATOM   7884 C  CA  . THR D 2 117 ? -24.028 -13.517 49.564  1   29.93  ? 287 THR D CA  1 
ATOM   7885 C  C   . THR D 2 117 ? -24.886 -12.467 48.849  1   31.03  ? 287 THR D C   1 
ATOM   7886 O  O   . THR D 2 117 ? -25.261 -12.636 47.692  1   28.05  ? 287 THR D O   1 
ATOM   7887 C  CB  . THR D 2 117 ? -22.55  -13.133 49.623  1   29.18  ? 287 THR D CB  1 
ATOM   7888 O  OG1 . THR D 2 117 ? -22.132 -12.736 48.316  1   28.26  ? 287 THR D OG1 1 
ATOM   7889 C  CG2 . THR D 2 117 ? -21.707 -14.265 50.182  1   25.74  ? 287 THR D CG2 1 
ATOM   7890 N  N   . LYS D 2 118 ? -25.162 -11.358 49.549  1   32.38  ? 288 LYS D N   1 
ATOM   7891 C  CA  . LYS D 2 118 ? -25.916 -10.253 48.986  1   29.67  ? 288 LYS D CA  1 
ATOM   7892 C  C   . LYS D 2 118 ? -25.204 -9.694  47.76   1   30.1   ? 288 LYS D C   1 
ATOM   7893 O  O   . LYS D 2 118 ? -25.88  -9.218  46.833  1   28.26  ? 288 LYS D O   1 
ATOM   7894 C  CB  . LYS D 2 118 ? -26.032 -9.151  50.036  1   27.34  ? 288 LYS D CB  1 
ATOM   7895 C  CG  . LYS D 2 118 ? -27.027 -8.027  49.798  1   24.77  ? 288 LYS D CG  1 
ATOM   7896 C  CD  . LYS D 2 118 ? -26.994 -7.147  51.056  1   27.06  ? 288 LYS D CD  1 
ATOM   7897 C  CE  . LYS D 2 118 ? -27.928 -5.994  51.163  1   26.79  ? 288 LYS D CE  1 
ATOM   7898 N  NZ  . LYS D 2 118 ? -27.711 -5.354  52.458  1   26.56  ? 288 LYS D NZ  1 
ATOM   7899 N  N   . LYS D 2 119 ? -23.855 -9.776  47.773  1   29.11  ? 289 LYS D N   1 
ATOM   7900 C  CA  . LYS D 2 119 ? -23.045 -9.18   46.717  1   28.03  ? 289 LYS D CA  1 
ATOM   7901 C  C   . LYS D 2 119 ? -23.212 -9.978  45.423  1   27.32  ? 289 LYS D C   1 
ATOM   7902 O  O   . LYS D 2 119 ? -23.294 -9.401  44.327  1   27.38  ? 289 LYS D O   1 
ATOM   7903 C  CB  . LYS D 2 119 ? -21.573 -8.992  47.087  1   28.48  ? 289 LYS D CB  1 
ATOM   7904 C  CG  . LYS D 2 119 ? -20.902 -7.991  46.143  1   33.17  ? 289 LYS D CG  1 
ATOM   7905 C  CD  . LYS D 2 119 ? -19.519 -7.499  46.547  1   38.68  ? 289 LYS D CD  1 
ATOM   7906 C  CE  . LYS D 2 119 ? -18.525 -8.623  46.586  1   42.36  ? 289 LYS D CE  1 
ATOM   7907 N  NZ  . LYS D 2 119 ? -17.187 -8.126  46.913  1   42.86  ? 289 LYS D NZ  1 
ATOM   7908 N  N   . GLN D 2 120 ? -23.291 -11.306 45.573  1   23.88  ? 290 GLN D N   1 
ATOM   7909 C  CA  . GLN D 2 120 ? -23.55  -12.155 44.425  1   26.08  ? 290 GLN D CA  1 
ATOM   7910 C  C   . GLN D 2 120 ? -24.914 -11.826 43.831  1   26.12  ? 290 GLN D C   1 
ATOM   7911 O  O   . GLN D 2 120 ? -25.057 -11.763 42.605  1   25.47  ? 290 GLN D O   1 
ATOM   7912 C  CB  . GLN D 2 120 ? -23.474 -13.625 44.798  1   25.58  ? 290 GLN D CB  1 
ATOM   7913 C  CG  . GLN D 2 120 ? -22.055 -14.062 45.133  1   27.15  ? 290 GLN D CG  1 
ATOM   7914 C  CD  . GLN D 2 120 ? -22.026 -15.519 45.522  1   27.71  ? 290 GLN D CD  1 
ATOM   7915 O  OE1 . GLN D 2 120 ? -22.458 -15.869 46.625  1   30.16  ? 290 GLN D OE1 1 
ATOM   7916 N  NE2 . GLN D 2 120 ? -21.606 -16.372 44.592  1   26.08  ? 290 GLN D NE2 1 
ATOM   7917 N  N   . VAL D 2 121 ? -25.896 -11.59  44.707  1   22.15  ? 291 VAL D N   1 
ATOM   7918 C  CA  . VAL D 2 121 ? -27.229 -11.342 44.207  1   21.89  ? 291 VAL D CA  1 
ATOM   7919 C  C   . VAL D 2 121 ? -27.223 -10.048 43.394  1   22.8   ? 291 VAL D C   1 
ATOM   7920 O  O   . VAL D 2 121 ? -27.765 -10.016 42.298  1   22.93  ? 291 VAL D O   1 
ATOM   7921 C  CB  . VAL D 2 121 ? -28.286 -11.36  45.319  1   21.55  ? 291 VAL D CB  1 
ATOM   7922 C  CG1 . VAL D 2 121 ? -29.599 -10.772 44.82   1   19.61  ? 291 VAL D CG1 1 
ATOM   7923 C  CG2 . VAL D 2 121 ? -28.458 -12.77  45.89   1   18.88  ? 291 VAL D CG2 1 
ATOM   7924 N  N   . LEU D 2 122 ? -26.513 -9.018  43.872  1   22.79  ? 292 LEU D N   1 
ATOM   7925 C  CA  . LEU D 2 122 ? -26.541 -7.726  43.201  1   22.76  ? 292 LEU D CA  1 
ATOM   7926 C  C   . LEU D 2 122 ? -25.703 -7.729  41.925  1   24.18  ? 292 LEU D C   1 
ATOM   7927 O  O   . LEU D 2 122 ? -26.053 -7.064  40.954  1   24.73  ? 292 LEU D O   1 
ATOM   7928 C  CB  . LEU D 2 122 ? -26.059 -6.68   44.198  1   22.42  ? 292 LEU D CB  1 
ATOM   7929 C  CG  . LEU D 2 122 ? -27.003 -6.452  45.387  1   22.51  ? 292 LEU D CG  1 
ATOM   7930 C  CD1 . LEU D 2 122 ? -26.428 -5.415  46.313  1   20.31  ? 292 LEU D CD1 1 
ATOM   7931 C  CD2 . LEU D 2 122 ? -28.405 -6.062  44.929  1   22.63  ? 292 LEU D CD2 1 
ATOM   7932 N  N   . ARG D 2 123 ? -24.584 -8.465  41.952  1   23.44  ? 293 ARG D N   1 
ATOM   7933 C  CA  . ARG D 2 123 ? -23.727 -8.57   40.794  1   23.14  ? 293 ARG D CA  1 
ATOM   7934 C  C   . ARG D 2 123 ? -24.474 -9.329  39.701  1   24.99  ? 293 ARG D C   1 
ATOM   7935 O  O   . ARG D 2 123 ? -24.399 -8.946  38.536  1   24.89  ? 293 ARG D O   1 
ATOM   7936 C  CB  . ARG D 2 123 ? -22.373 -9.149  41.199  1   25.88  ? 293 ARG D CB  1 
ATOM   7937 C  CG  . ARG D 2 123 ? -21.425 -8.114  41.787  1   30.38  ? 293 ARG D CG  1 
ATOM   7938 C  CD  . ARG D 2 123 ? -20.096 -8.71   42.232  1   45.76  ? 293 ARG D CD  1 
ATOM   7939 N  NE  . ARG D 2 123 ? -19.398 -9.359  41.109  1   72.52  ? 293 ARG D NE  1 
ATOM   7940 C  CZ  . ARG D 2 123 ? -19.102 -10.664 40.89   1   77.61  ? 293 ARG D CZ  1 
ATOM   7941 N  NH1 . ARG D 2 123 ? -19.332 -11.62  41.8    1   70.24  ? 293 ARG D NH1 1 
ATOM   7942 N  NH2 . ARG D 2 123 ? -18.573 -10.997 39.719  1   65.53  ? 293 ARG D NH2 1 
ATOM   7943 N  N   . MET D 2 124 ? -25.231 -10.372 40.088  1   25.17  ? 294 MET D N   1 
ATOM   7944 C  CA  . MET D 2 124 ? -26.009 -11.155 39.139  1   22.21  ? 294 MET D CA  1 
ATOM   7945 C  C   . MET D 2 124 ? -27.126 -10.276 38.592  1   23.87  ? 294 MET D C   1 
ATOM   7946 O  O   . MET D 2 124 ? -27.451 -10.341 37.402  1   22.78  ? 294 MET D O   1 
ATOM   7947 C  CB  . MET D 2 124 ? -26.649 -12.39  39.78   1   21.42  ? 294 MET D CB  1 
ATOM   7948 C  CG  . MET D 2 124 ? -27.512 -13.209 38.817  1   21.62  ? 294 MET D CG  1 
ATOM   7949 S  SD  . MET D 2 124 ? -26.587 -13.961 37.449  1   24.3   ? 294 MET D SD  1 
ATOM   7950 C  CE  . MET D 2 124 ? -25.746 -15.306 38.298  1   22.8   ? 294 MET D CE  1 
ATOM   7951 N  N   . GLU D 2 125 ? -27.708 -9.457  39.477  1   23.06  ? 295 GLU D N   1 
ATOM   7952 C  CA  . GLU D 2 125 ? -28.708 -8.504  39.033  1   23.89  ? 295 GLU D CA  1 
ATOM   7953 C  C   . GLU D 2 125 ? -28.17  -7.725  37.833  1   24.34  ? 295 GLU D C   1 
ATOM   7954 O  O   . GLU D 2 125 ? -28.825 -7.637  36.795  1   24.23  ? 295 GLU D O   1 
ATOM   7955 C  CB  . GLU D 2 125 ? -29.11  -7.51   40.123  1   22.89  ? 295 GLU D CB  1 
ATOM   7956 C  CG  . GLU D 2 125 ? -30.278 -6.633  39.679  1   22.32  ? 295 GLU D CG  1 
ATOM   7957 C  CD  . GLU D 2 125 ? -30.71  -5.577  40.669  1   24.76  ? 295 GLU D CD  1 
ATOM   7958 O  OE1 . GLU D 2 125 ? -29.841 -4.773  41.066  1   28.17  ? 295 GLU D OE1 1 
ATOM   7959 O  OE2 . GLU D 2 125 ? -31.914 -5.545  41.02   1   25.7   ? 295 GLU D OE2 1 
ATOM   7960 N  N   . HIS D 2 126 ? -26.971 -7.164  38      1   24.31  ? 296 HIS D N   1 
ATOM   7961 C  CA  . HIS D 2 126 ? -26.401 -6.34   36.955  1   26.87  ? 296 HIS D CA  1 
ATOM   7962 C  C   . HIS D 2 126 ? -26.155 -7.21   35.715  1   27.94  ? 296 HIS D C   1 
ATOM   7963 O  O   . HIS D 2 126 ? -26.423 -6.784  34.585  1   27.69  ? 296 HIS D O   1 
ATOM   7964 C  CB  . HIS D 2 126 ? -25.205 -5.547  37.503  1   26.11  ? 296 HIS D CB  1 
ATOM   7965 C  CG  . HIS D 2 126 ? -24.86  -4.357  36.681  1   30.58  ? 296 HIS D CG  1 
ATOM   7966 N  ND1 . HIS D 2 126 ? -23.789 -3.539  36.962  1   35.42  ? 296 HIS D ND1 1 
ATOM   7967 C  CD2 . HIS D 2 126 ? -25.457 -3.811  35.602  1   32.8   ? 296 HIS D CD2 1 
ATOM   7968 C  CE1 . HIS D 2 126 ? -23.74  -2.556  36.059  1   34.34  ? 296 HIS D CE1 1 
ATOM   7969 N  NE2 . HIS D 2 126 ? -24.743 -2.706  35.223  1   31.7   ? 296 HIS D NE2 1 
ATOM   7970 N  N   . LEU D 2 127 ? -25.656 -8.436  35.923  1   24.86  ? 297 LEU D N   1 
ATOM   7971 C  CA  . LEU D 2 127 ? -25.335 -9.268  34.779  1   24.86  ? 297 LEU D CA  1 
ATOM   7972 C  C   . LEU D 2 127 ? -26.612 -9.523  33.981  1   24.41  ? 297 LEU D C   1 
ATOM   7973 O  O   . LEU D 2 127 ? -26.636 -9.354  32.77   1   27.36  ? 297 LEU D O   1 
ATOM   7974 C  CB  . LEU D 2 127 ? -24.649 -10.573 35.179  1   24.35  ? 297 LEU D CB  1 
ATOM   7975 C  CG  . LEU D 2 127 ? -24.29  -11.519 34.025  1   22.92  ? 297 LEU D CG  1 
ATOM   7976 C  CD1 . LEU D 2 127 ? -23.338 -10.892 33.005  1   17.33  ? 297 LEU D CD1 1 
ATOM   7977 C  CD2 . LEU D 2 127 ? -23.691 -12.783 34.605  1   23.15  ? 297 LEU D CD2 1 
ATOM   7978 N  N   . VAL D 2 128 ? -27.689 -9.886  34.67   1   21.49  ? 298 VAL D N   1 
ATOM   7979 C  CA  . VAL D 2 128 ? -28.939 -10.179 33.998  1   21.66  ? 298 VAL D CA  1 
ATOM   7980 C  C   . VAL D 2 128 ? -29.43  -8.96   33.22   1   24.82  ? 298 VAL D C   1 
ATOM   7981 O  O   . VAL D 2 128 ? -30.045 -9.106  32.157  1   30.24  ? 298 VAL D O   1 
ATOM   7982 C  CB  . VAL D 2 128 ? -30.029 -10.676 34.96   1   21.31  ? 298 VAL D CB  1 
ATOM   7983 C  CG1 . VAL D 2 128 ? -31.381 -10.713 34.263  1   22.31  ? 298 VAL D CG1 1 
ATOM   7984 C  CG2 . VAL D 2 128 ? -29.696 -12.043 35.552  1   18.91  ? 298 VAL D CG2 1 
ATOM   7985 N  N   . LEU D 2 129 ? -29.222 -7.764  33.77   1   22.69  ? 299 LEU D N   1 
ATOM   7986 C  CA  . LEU D 2 129 ? -29.703 -6.584  33.087  1   23.31  ? 299 LEU D CA  1 
ATOM   7987 C  C   . LEU D 2 129 ? -28.942 -6.364  31.773  1   25.74  ? 299 LEU D C   1 
ATOM   7988 O  O   . LEU D 2 129 ? -29.539 -5.956  30.771  1   24.33  ? 299 LEU D O   1 
ATOM   7989 C  CB  . LEU D 2 129 ? -29.608 -5.394  34.031  1   23.89  ? 299 LEU D CB  1 
ATOM   7990 C  CG  . LEU D 2 129 ? -30.755 -5.207  35.025  1   24.17  ? 299 LEU D CG  1 
ATOM   7991 C  CD1 . LEU D 2 129 ? -30.297 -4.134  36.004  1   23.36  ? 299 LEU D CD1 1 
ATOM   7992 C  CD2 . LEU D 2 129 ? -32.052 -4.782  34.338  1   22.49  ? 299 LEU D CD2 1 
ATOM   7993 N  N   . LYS D 2 130 ? -27.632 -6.65   31.773  1   25.63  ? 300 LYS D N   1 
ATOM   7994 C  CA  . LYS D 2 130 ? -26.806 -6.413  30.604  1   27.4   ? 300 LYS D CA  1 
ATOM   7995 C  C   . LYS D 2 130 ? -27.14  -7.445  29.53   1   28.12  ? 300 LYS D C   1 
ATOM   7996 O  O   . LYS D 2 130 ? -27.214 -7.107  28.347  1   28.71  ? 300 LYS D O   1 
ATOM   7997 C  CB  . LYS D 2 130 ? -25.298 -6.447  30.878  1   29.56  ? 300 LYS D CB  1 
ATOM   7998 C  CG  . LYS D 2 130 ? -24.786 -5.474  31.945  1   35.27  ? 300 LYS D CG  1 
ATOM   7999 C  CD  . LYS D 2 130 ? -23.265 -5.327  32.069  1   39.03  ? 300 LYS D CD  1 
ATOM   8000 C  CE  . LYS D 2 130 ? -22.776 -5.479  33.491  1   44.66  ? 300 LYS D CE  1 
ATOM   8001 N  NZ  . LYS D 2 130 ? -21.448 -4.895  33.721  1   51.02  ? 300 LYS D NZ  1 
ATOM   8002 N  N   . VAL D 2 131 ? -27.343 -8.694  29.956  1   26.3   ? 301 VAL D N   1 
ATOM   8003 C  CA  . VAL D 2 131 ? -27.62  -9.783  29.036  1   26.26  ? 301 VAL D CA  1 
ATOM   8004 C  C   . VAL D 2 131 ? -28.962 -9.564  28.343  1   29.11  ? 301 VAL D C   1 
ATOM   8005 O  O   . VAL D 2 131 ? -29.07  -9.818  27.144  1   29.38  ? 301 VAL D O   1 
ATOM   8006 C  CB  . VAL D 2 131 ? -27.568 -11.149 29.732  1   25.55  ? 301 VAL D CB  1 
ATOM   8007 C  CG1 . VAL D 2 131 ? -28.199 -12.252 28.887  1   25.95  ? 301 VAL D CG1 1 
ATOM   8008 C  CG2 . VAL D 2 131 ? -26.143 -11.526 30.113  1   23.46  ? 301 VAL D CG2 1 
ATOM   8009 N  N   . LEU D 2 132 ? -29.972 -9.115  29.108  1   28.46  ? 302 LEU D N   1 
ATOM   8010 C  CA  . LEU D 2 132 ? -31.288 -8.814  28.569  1   24.7   ? 302 LEU D CA  1 
ATOM   8011 C  C   . LEU D 2 132 ? -31.303 -7.433  27.926  1   27.12  ? 302 LEU D C   1 
ATOM   8012 O  O   . LEU D 2 132 ? -32.33  -7.029  27.403  1   31.77  ? 302 LEU D O   1 
ATOM   8013 C  CB  . LEU D 2 132 ? -32.331 -8.881  29.671  1   23.61  ? 302 LEU D CB  1 
ATOM   8014 C  CG  . LEU D 2 132 ? -32.518 -10.262 30.306  1   25.98  ? 302 LEU D CG  1 
ATOM   8015 C  CD1 . LEU D 2 132 ? -33.701 -10.309 31.262  1   23.79  ? 302 LEU D CD1 1 
ATOM   8016 C  CD2 . LEU D 2 132 ? -32.665 -11.342 29.246  1   23.49  ? 302 LEU D CD2 1 
ATOM   8017 N  N   . ALA D 2 133 ? -30.207 -6.678  28.037  1   27.37  ? 303 ALA D N   1 
ATOM   8018 C  CA  . ALA D 2 133 ? -30.146 -5.297  27.567  1   28.81  ? 303 ALA D CA  1 
ATOM   8019 C  C   . ALA D 2 133 ? -31.28  -4.438  28.137  1   30.37  ? 303 ALA D C   1 
ATOM   8020 O  O   . ALA D 2 133 ? -31.788 -3.554  27.458  1   32.8   ? 303 ALA D O   1 
ATOM   8021 C  CB  . ALA D 2 133 ? -30.121 -5.241  26.055  1   23.08  ? 303 ALA D CB  1 
ATOM   8022 N  N   . PHE D 2 134 ? -31.665 -4.687  29.39   1   31.57  ? 304 PHE D N   1 
ATOM   8023 C  CA  . PHE D 2 134 ? -32.711 -3.93   30.055  1   33.23  ? 304 PHE D CA  1 
ATOM   8024 C  C   . PHE D 2 134 ? -34.049 -4.115  29.368  1   34.12  ? 304 PHE D C   1 
ATOM   8025 O  O   . PHE D 2 134 ? -34.941 -3.317  29.612  1   34.89  ? 304 PHE D O   1 
ATOM   8026 C  CB  . PHE D 2 134 ? -32.445 -2.42   30.097  1   32.59  ? 304 PHE D CB  1 
ATOM   8027 C  CG  . PHE D 2 134 ? -31.561 -1.99   31.252  1   36.12  ? 304 PHE D CG  1 
ATOM   8028 C  CD1 . PHE D 2 134 ? -30.169 -2.021  31.13   1   35.44  ? 304 PHE D CD1 1 
ATOM   8029 C  CD2 . PHE D 2 134 ? -32.123 -1.587  32.462  1   35.58  ? 304 PHE D CD2 1 
ATOM   8030 C  CE1 . PHE D 2 134 ? -29.358 -1.652  32.199  1   34.31  ? 304 PHE D CE1 1 
ATOM   8031 C  CE2 . PHE D 2 134 ? -31.303 -1.199  33.517  1   35.91  ? 304 PHE D CE2 1 
ATOM   8032 C  CZ  . PHE D 2 134 ? -29.929 -1.24   33.385  1   34.84  ? 304 PHE D CZ  1 
ATOM   8033 N  N   . ASP D 2 135 ? -34.161 -5.066  28.444  1   41.35  ? 305 ASP D N   1 
ATOM   8034 C  CA  . ASP D 2 135 ? -35.47  -5.338  27.78   1   40.57  ? 305 ASP D CA  1 
ATOM   8035 C  C   . ASP D 2 135 ? -36.299 -6.141  28.768  1   36.13  ? 305 ASP D C   1 
ATOM   8036 O  O   . ASP D 2 135 ? -36.33  -7.371  28.662  1   34.14  ? 305 ASP D O   1 
ATOM   8037 C  CB  . ASP D 2 135 ? -35.307 -5.935  26.397  1   51.24  ? 305 ASP D CB  1 
ATOM   8038 C  CG  . ASP D 2 135 ? -34.78  -4.974  25.347  1   73.79  ? 305 ASP D CG  1 
ATOM   8039 O  OD1 . ASP D 2 135 ? -34.799 -3.753  25.607  1   88.65  ? 305 ASP D OD1 1 
ATOM   8040 O  OD2 . ASP D 2 135 ? -34.363 -5.458  24.277  1   84.88  ? 305 ASP D OD2 1 
ATOM   8041 N  N   . LEU D 2 136 ? -36.969 -5.437  29.668  1   32.17  ? 306 LEU D N   1 
ATOM   8042 C  CA  . LEU D 2 136 ? -37.636 -6.119  30.762  1   29.37  ? 306 LEU D CA  1 
ATOM   8043 C  C   . LEU D 2 136 ? -39.147 -6.121  30.59   1   27.7   ? 306 LEU D C   1 
ATOM   8044 O  O   . LEU D 2 136 ? -39.807 -6.889  31.288  1   28.79  ? 306 LEU D O   1 
ATOM   8045 C  CB  . LEU D 2 136 ? -37.282 -5.493  32.107  1   33.09  ? 306 LEU D CB  1 
ATOM   8046 C  CG  . LEU D 2 136 ? -35.847 -5.632  32.623  1   34.04  ? 306 LEU D CG  1 
ATOM   8047 C  CD1 . LEU D 2 136 ? -35.952 -5.701  34.145  1   36.97  ? 306 LEU D CD1 1 
ATOM   8048 C  CD2 . LEU D 2 136 ? -35.093 -6.835  32.089  1   32.57  ? 306 LEU D CD2 1 
ATOM   8049 N  N   . ALA D 2 137 ? -39.697 -5.261  29.716  1   24.87  ? 307 ALA D N   1 
ATOM   8050 C  CA  . ALA D 2 137 ? -41.151 -5.156  29.648  1   27.04  ? 307 ALA D CA  1 
ATOM   8051 C  C   . ALA D 2 137 ? -41.755 -6.265  28.767  1   29.88  ? 307 ALA D C   1 
ATOM   8052 O  O   . ALA D 2 137 ? -42.291 -5.991  27.689  1   31.21  ? 307 ALA D O   1 
ATOM   8053 C  CB  . ALA D 2 137 ? -41.546 -3.762  29.203  1   24.86  ? 307 ALA D CB  1 
ATOM   8054 N  N   . ALA D 2 138 ? -41.684 -7.52   29.237  1   27.21  ? 308 ALA D N   1 
ATOM   8055 C  CA  . ALA D 2 138 ? -42.008 -8.664  28.393  1   27.94  ? 308 ALA D CA  1 
ATOM   8056 C  C   . ALA D 2 138 ? -43.483 -8.964  28.508  1   32.19  ? 308 ALA D C   1 
ATOM   8057 O  O   . ALA D 2 138 ? -44.021 -9.036  29.614  1   37.67  ? 308 ALA D O   1 
ATOM   8058 C  CB  . ALA D 2 138 ? -41.242 -9.899  28.795  1   25.77  ? 308 ALA D CB  1 
ATOM   8059 N  N   . PRO D 2 139 ? -44.168 -9.213  27.377  1   31.31  ? 309 PRO D N   1 
ATOM   8060 C  CA  . PRO D 2 139 ? -45.567 -9.633  27.438  1   31.35  ? 309 PRO D CA  1 
ATOM   8061 C  C   . PRO D 2 139 ? -45.594 -11.009 28.108  1   30.11  ? 309 PRO D C   1 
ATOM   8062 O  O   . PRO D 2 139 ? -44.757 -11.861 27.803  1   31.53  ? 309 PRO D O   1 
ATOM   8063 C  CB  . PRO D 2 139 ? -46.011 -9.641  25.966  1   32.13  ? 309 PRO D CB  1 
ATOM   8064 C  CG  . PRO D 2 139 ? -44.936 -8.849  25.239  1   32.23  ? 309 PRO D CG  1 
ATOM   8065 C  CD  . PRO D 2 139 ? -43.642 -9.124  26.011  1   29.27  ? 309 PRO D CD  1 
ATOM   8066 N  N   . THR D 2 140 ? -46.526 -11.187 29.056  1   27.6   ? 310 THR D N   1 
ATOM   8067 C  CA  . THR D 2 140 ? -46.712 -12.423 29.81   1   26.71  ? 310 THR D CA  1 
ATOM   8068 C  C   . THR D 2 140 ? -48.024 -13.095 29.409  1   27.73  ? 310 THR D C   1 
ATOM   8069 O  O   . THR D 2 140 ? -48.926 -12.469 28.834  1   25.72  ? 310 THR D O   1 
ATOM   8070 C  CB  . THR D 2 140 ? -46.767 -12.146 31.317  1   25.95  ? 310 THR D CB  1 
ATOM   8071 O  OG1 . THR D 2 140 ? -47.818 -11.211 31.562  1   25.84  ? 310 THR D OG1 1 
ATOM   8072 C  CG2 . THR D 2 140 ? -45.471 -11.603 31.872  1   24.83  ? 310 THR D CG2 1 
ATOM   8073 N  N   . ILE D 2 141 ? -48.143 -14.36  29.824  1   27.8   ? 311 ILE D N   1 
ATOM   8074 C  CA  . ILE D 2 141 ? -49.385 -15.095 29.677  1   28.09  ? 311 ILE D CA  1 
ATOM   8075 C  C   . ILE D 2 141 ? -50.51  -14.303 30.332  1   31.84  ? 311 ILE D C   1 
ATOM   8076 O  O   . ILE D 2 141 ? -51.605 -14.231 29.769  1   34.94  ? 311 ILE D O   1 
ATOM   8077 C  CB  . ILE D 2 141 ? -49.228 -16.498 30.278  1   26.24  ? 311 ILE D CB  1 
ATOM   8078 C  CG1 . ILE D 2 141 ? -48.466 -17.414 29.31   1   26.26  ? 311 ILE D CG1 1 
ATOM   8079 C  CG2 . ILE D 2 141 ? -50.581 -17.075 30.686  1   21.9   ? 311 ILE D CG2 1 
ATOM   8080 C  CD1 . ILE D 2 141 ? -47.887 -18.644 29.983  1   24.04  ? 311 ILE D CD1 1 
ATOM   8081 N  N   . ASN D 2 142 ? -50.227 -13.691 31.5    1   30.94  ? 312 ASN D N   1 
ATOM   8082 C  CA  . ASN D 2 142 ? -51.244 -12.946 32.227  1   30.86  ? 312 ASN D CA  1 
ATOM   8083 C  C   . ASN D 2 142 ? -51.716 -11.747 31.415  1   29.26  ? 312 ASN D C   1 
ATOM   8084 O  O   . ASN D 2 142 ? -52.904 -11.434 31.418  1   31.79  ? 312 ASN D O   1 
ATOM   8085 C  CB  . ASN D 2 142 ? -50.81  -12.526 33.624  1   33.97  ? 312 ASN D CB  1 
ATOM   8086 C  CG  . ASN D 2 142 ? -50.841 -13.694 34.574  1   39.56  ? 312 ASN D CG  1 
ATOM   8087 O  OD1 . ASN D 2 142 ? -50.83  -14.848 34.135  1   47.79  ? 312 ASN D OD1 1 
ATOM   8088 N  ND2 . ASN D 2 142 ? -50.86  -13.424 35.869  1   36.69  ? 312 ASN D ND2 1 
ATOM   8089 N  N   . GLN D 2 143 ? -50.792 -11.084 30.718  1   26.82  ? 313 GLN D N   1 
ATOM   8090 C  CA  . GLN D 2 143 ? -51.164 -9.864  30.017  1   26.41  ? 313 GLN D CA  1 
ATOM   8091 C  C   . GLN D 2 143 ? -52.177 -10.171 28.919  1   24.88  ? 313 GLN D C   1 
ATOM   8092 O  O   . GLN D 2 143 ? -52.995 -9.327  28.565  1   25.13  ? 313 GLN D O   1 
ATOM   8093 C  CB  . GLN D 2 143 ? -49.952 -9.148  29.431  1   24.36  ? 313 GLN D CB  1 
ATOM   8094 C  CG  . GLN D 2 143 ? -49.172 -8.38   30.476  1   24.99  ? 313 GLN D CG  1 
ATOM   8095 C  CD  . GLN D 2 143 ? -47.943 -7.737  29.882  1   28.78  ? 313 GLN D CD  1 
ATOM   8096 O  OE1 . GLN D 2 143 ? -48.053 -6.977  28.911  1   30.33  ? 313 GLN D OE1 1 
ATOM   8097 N  NE2 . GLN D 2 143 ? -46.777 -8.039  30.458  1   26.36  ? 313 GLN D NE2 1 
ATOM   8098 N  N   . PHE D 2 144 ? -52.096 -11.385 28.373  1   24.25  ? 314 PHE D N   1 
ATOM   8099 C  CA  . PHE D 2 144 ? -53.034 -11.804 27.353  1   22.97  ? 314 PHE D CA  1 
ATOM   8100 C  C   . PHE D 2 144 ? -54.315 -12.283 28.021  1   24.53  ? 314 PHE D C   1 
ATOM   8101 O  O   . PHE D 2 144 ? -55.396 -11.948 27.535  1   24.86  ? 314 PHE D O   1 
ATOM   8102 C  CB  . PHE D 2 144 ? -52.395 -12.842 26.438  1   21.73  ? 314 PHE D CB  1 
ATOM   8103 C  CG  . PHE D 2 144 ? -51.356 -12.227 25.53   1   23.36  ? 314 PHE D CG  1 
ATOM   8104 C  CD1 . PHE D 2 144 ? -51.744 -11.506 24.401  1   25.83  ? 314 PHE D CD1 1 
ATOM   8105 C  CD2 . PHE D 2 144 ? -50     -12.353 25.817  1   23.75  ? 314 PHE D CD2 1 
ATOM   8106 C  CE1 . PHE D 2 144 ? -50.786 -10.939 23.562  1   26.35  ? 314 PHE D CE1 1 
ATOM   8107 C  CE2 . PHE D 2 144 ? -49.053 -11.775 24.988  1   24.37  ? 314 PHE D CE2 1 
ATOM   8108 C  CZ  . PHE D 2 144 ? -49.446 -11.079 23.857  1   24.25  ? 314 PHE D CZ  1 
ATOM   8109 N  N   . LEU D 2 145 ? -54.183 -13.047 29.122  1   23.96  ? 315 LEU D N   1 
ATOM   8110 C  CA  . LEU D 2 145 ? -55.346 -13.577 29.822  1   27.02  ? 315 LEU D CA  1 
ATOM   8111 C  C   . LEU D 2 145 ? -56.313 -12.456 30.201  1   27.68  ? 315 LEU D C   1 
ATOM   8112 O  O   . LEU D 2 145 ? -57.484 -12.496 29.811  1   26.28  ? 315 LEU D O   1 
ATOM   8113 C  CB  . LEU D 2 145 ? -54.974 -14.399 31.056  1   28.22  ? 315 LEU D CB  1 
ATOM   8114 C  CG  . LEU D 2 145 ? -54.516 -15.837 30.801  1   28.31  ? 315 LEU D CG  1 
ATOM   8115 C  CD1 . LEU D 2 145 ? -54.238 -16.504 32.128  1   28.27  ? 315 LEU D CD1 1 
ATOM   8116 C  CD2 . LEU D 2 145 ? -55.526 -16.63  30.011  1   26.48  ? 315 LEU D CD2 1 
ATOM   8117 N  N   . THR D 2 146 ? -55.797 -11.459 30.944  1   25.03  ? 316 THR D N   1 
ATOM   8118 C  CA  . THR D 2 146 ? -56.651 -10.413 31.472  1   25     ? 316 THR D CA  1 
ATOM   8119 C  C   . THR D 2 146 ? -57.413 -9.761  30.323  1   27.94  ? 316 THR D C   1 
ATOM   8120 O  O   . THR D 2 146 ? -58.573 -9.378  30.486  1   33.96  ? 316 THR D O   1 
ATOM   8121 C  CB  . THR D 2 146 ? -55.872 -9.387  32.29   1   24.53  ? 316 THR D CB  1 
ATOM   8122 O  OG1 . THR D 2 146 ? -55.063 -8.654  31.38   1   26.42  ? 316 THR D OG1 1 
ATOM   8123 C  CG2 . THR D 2 146 ? -55.001 -10.002 33.37   1   24.38  ? 316 THR D CG2 1 
ATOM   8124 N  N   . GLN D 2 147 ? -56.752 -9.621  29.169  1   26.65  ? 317 GLN D N   1 
ATOM   8125 C  CA  . GLN D 2 147 ? -57.362 -9.056  27.973  1   26.94  ? 317 GLN D CA  1 
ATOM   8126 C  C   . GLN D 2 147 ? -58.487 -9.953  27.45   1   27.58  ? 317 GLN D C   1 
ATOM   8127 O  O   . GLN D 2 147 ? -59.499 -9.459  26.94   1   25.75  ? 317 GLN D O   1 
ATOM   8128 C  CB  . GLN D 2 147 ? -56.324 -8.811  26.872  1   27.63  ? 317 GLN D CB  1 
ATOM   8129 C  CG  . GLN D 2 147 ? -55.682 -7.428  26.915  1   30.02  ? 317 GLN D CG  1 
ATOM   8130 C  CD  . GLN D 2 147 ? -54.778 -7.113  25.742  1   32.72  ? 317 GLN D CD  1 
ATOM   8131 O  OE1 . GLN D 2 147 ? -53.552 -7.109  25.892  1   39.78  ? 317 GLN D OE1 1 
ATOM   8132 N  NE2 . GLN D 2 147 ? -55.353 -6.831  24.574  1   31.42  ? 317 GLN D NE2 1 
ATOM   8133 N  N   . TYR D 2 148 ? -58.272 -11.274 27.533  1   29.74  ? 318 TYR D N   1 
ATOM   8134 C  CA  . TYR D 2 148 ? -59.221 -12.258 27.034  1   29.33  ? 318 TYR D CA  1 
ATOM   8135 C  C   . TYR D 2 148 ? -60.468 -12.287 27.926  1   32.65  ? 318 TYR D C   1 
ATOM   8136 O  O   . TYR D 2 148 ? -61.58  -12.511 27.429  1   31.75  ? 318 TYR D O   1 
ATOM   8137 C  CB  . TYR D 2 148 ? -58.566 -13.636 26.918  1   25.58  ? 318 TYR D CB  1 
ATOM   8138 C  CG  . TYR D 2 148 ? -57.429 -13.821 25.924  1   24.59  ? 318 TYR D CG  1 
ATOM   8139 C  CD1 . TYR D 2 148 ? -57.137 -12.898 24.919  1   23.33  ? 318 TYR D CD1 1 
ATOM   8140 C  CD2 . TYR D 2 148 ? -56.633 -14.955 26.009  1   24.64  ? 318 TYR D CD2 1 
ATOM   8141 C  CE1 . TYR D 2 148 ? -56.076 -13.11  24.044  1   24.11  ? 318 TYR D CE1 1 
ATOM   8142 C  CE2 . TYR D 2 148 ? -55.584 -15.183 25.133  1   24.42  ? 318 TYR D CE2 1 
ATOM   8143 C  CZ  . TYR D 2 148 ? -55.299 -14.26  24.141  1   24.69  ? 318 TYR D CZ  1 
ATOM   8144 O  OH  . TYR D 2 148 ? -54.239 -14.557 23.311  1   24.7   ? 318 TYR D OH  1 
ATOM   8145 N  N   . PHE D 2 149 ? -60.271 -12.058 29.237  1   33.15  ? 319 PHE D N   1 
ATOM   8146 C  CA  . PHE D 2 149 ? -61.342 -12.13  30.222  1   34.69  ? 319 PHE D CA  1 
ATOM   8147 C  C   . PHE D 2 149 ? -62.434 -11.111 29.903  1   35.55  ? 319 PHE D C   1 
ATOM   8148 O  O   . PHE D 2 149 ? -63.61  -11.353 30.185  1   36.69  ? 319 PHE D O   1 
ATOM   8149 C  CB  . PHE D 2 149 ? -60.812 -11.899 31.635  1   33.75  ? 319 PHE D CB  1 
ATOM   8150 C  CG  . PHE D 2 149 ? -59.893 -12.976 32.191  1   34.31  ? 319 PHE D CG  1 
ATOM   8151 C  CD1 . PHE D 2 149 ? -59.789 -14.228 31.584  1   33.82  ? 319 PHE D CD1 1 
ATOM   8152 C  CD2 . PHE D 2 149 ? -59.153 -12.728 33.349  1   34.92  ? 319 PHE D CD2 1 
ATOM   8153 C  CE1 . PHE D 2 149 ? -58.948 -15.194 32.123  1   37.19  ? 319 PHE D CE1 1 
ATOM   8154 C  CE2 . PHE D 2 149 ? -58.316 -13.695 33.891  1   34.15  ? 319 PHE D CE2 1 
ATOM   8155 C  CZ  . PHE D 2 149 ? -58.202 -14.92  33.272  1   36.97  ? 319 PHE D CZ  1 
ATOM   8156 N  N   . LEU D 2 150 ? -62.037 -9.994  29.282  1   34.71  ? 320 LEU D N   1 
ATOM   8157 C  CA  . LEU D 2 150 ? -62.952 -8.936  28.871  1   35.89  ? 320 LEU D CA  1 
ATOM   8158 C  C   . LEU D 2 150 ? -64.026 -9.45   27.9    1   36.38  ? 320 LEU D C   1 
ATOM   8159 O  O   . LEU D 2 150 ? -65.109 -8.871  27.805  1   37.72  ? 320 LEU D O   1 
ATOM   8160 C  CB  . LEU D 2 150 ? -62.147 -7.775  28.281  1   34.37  ? 320 LEU D CB  1 
ATOM   8161 C  CG  . LEU D 2 150 ? -61.233 -7.017  29.252  1   34.28  ? 320 LEU D CG  1 
ATOM   8162 C  CD1 . LEU D 2 150 ? -60.485 -5.902  28.518  1   31.39  ? 320 LEU D CD1 1 
ATOM   8163 C  CD2 . LEU D 2 150 ? -62.001 -6.465  30.454  1   31.38  ? 320 LEU D CD2 1 
ATOM   8164 N  N   . HIS D 2 151 ? -63.736 -10.54  27.179  1   35.02  ? 321 HIS D N   1 
ATOM   8165 C  CA  . HIS D 2 151 ? -64.664 -11.066 26.193  1   32.54  ? 321 HIS D CA  1 
ATOM   8166 C  C   . HIS D 2 151 ? -65.74  -11.952 26.822  1   33.47  ? 321 HIS D C   1 
ATOM   8167 O  O   . HIS D 2 151 ? -66.726 -12.286 26.157  1   33.84  ? 321 HIS D O   1 
ATOM   8168 C  CB  . HIS D 2 151 ? -63.886 -11.736 25.065  1   35     ? 321 HIS D CB  1 
ATOM   8169 C  CG  . HIS D 2 151 ? -63.216 -10.749 24.172  1   37.37  ? 321 HIS D CG  1 
ATOM   8170 N  ND1 . HIS D 2 151 ? -63.525 -10.612 22.833  1   36.77  ? 321 HIS D ND1 1 
ATOM   8171 C  CD2 . HIS D 2 151 ? -62.249 -9.855  24.432  1   35.7   ? 321 HIS D CD2 1 
ATOM   8172 C  CE1 . HIS D 2 151 ? -62.763 -9.663  22.309  1   36.23  ? 321 HIS D CE1 1 
ATOM   8173 N  NE2 . HIS D 2 151 ? -61.981 -9.188  23.264  1   35.54  ? 321 HIS D NE2 1 
ATOM   8174 N  N   . GLN D 2 152 ? -65.573 -12.251 28.105  1   33.47  ? 322 GLN D N   1 
ATOM   8175 C  CA  . GLN D 2 152 ? -66.594 -13.033 28.831  1   35.34  ? 322 GLN D CA  1 
ATOM   8176 C  C   . GLN D 2 152 ? -67.874 -12.205 28.934  1   39.3   ? 322 GLN D C   1 
ATOM   8177 O  O   . GLN D 2 152 ? -67.769 -10.979 29.082  1   41.22  ? 322 GLN D O   1 
ATOM   8178 C  CB  . GLN D 2 152 ? -66.135 -13.356 30.246  1   33.67  ? 322 GLN D CB  1 
ATOM   8179 C  CG  . GLN D 2 152 ? -65.016 -14.381 30.359  1   36.14  ? 322 GLN D CG  1 
ATOM   8180 C  CD  . GLN D 2 152 ? -64.547 -14.546 31.787  1   39.15  ? 322 GLN D CD  1 
ATOM   8181 O  OE1 . GLN D 2 152 ? -64.759 -15.582 32.424  1   41.52  ? 322 GLN D OE1 1 
ATOM   8182 N  NE2 . GLN D 2 152 ? -63.927 -13.502 32.314  1   43.05  ? 322 GLN D NE2 1 
ATOM   8183 N  N   . GLN D 2 153 ? -69.03  -12.858 28.849  1   42.95  ? 323 GLN D N   1 
ATOM   8184 C  CA  . GLN D 2 153 ? -70.343 -12.177 28.99   1   47.26  ? 323 GLN D CA  1 
ATOM   8185 C  C   . GLN D 2 153 ? -71.352 -13.216 29.506  1   45.18  ? 323 GLN D C   1 
ATOM   8186 O  O   . GLN D 2 153 ? -72.019 -13.865 28.686  1   43.11  ? 323 GLN D O   1 
ATOM   8187 C  CB  . GLN D 2 153 ? -70.851 -11.558 27.687  1   52.75  ? 323 GLN D CB  1 
ATOM   8188 C  CG  . GLN D 2 153 ? -71.151 -12.552 26.57   1   55.63  ? 323 GLN D CG  1 
ATOM   8189 C  CD  . GLN D 2 153 ? -71.65  -11.887 25.305  1   58.99  ? 323 GLN D CD  1 
ATOM   8190 O  OE1 . GLN D 2 153 ? -71.451 -10.688 25.083  1   54.41  ? 323 GLN D OE1 1 
ATOM   8191 N  NE2 . GLN D 2 153 ? -72.307 -12.664 24.458  1   59.05  ? 323 GLN D NE2 1 
ATOM   8192 N  N   . PRO D 2 154 ? -71.467 -13.415 30.831  1   42.72  ? 324 PRO D N   1 
ATOM   8193 C  CA  . PRO D 2 154 ? -70.843 -12.52  31.785  1   40.92  ? 324 PRO D CA  1 
ATOM   8194 C  C   . PRO D 2 154 ? -69.471 -13     32.202  1   43.67  ? 324 PRO D C   1 
ATOM   8195 O  O   . PRO D 2 154 ? -68.971 -14.024 31.699  1   39.77  ? 324 PRO D O   1 
ATOM   8196 C  CB  . PRO D 2 154 ? -71.843 -12.646 32.924  1   38.79  ? 324 PRO D CB  1 
ATOM   8197 C  CG  . PRO D 2 154 ? -72.178 -14.116 32.932  1   38.12  ? 324 PRO D CG  1 
ATOM   8198 C  CD  . PRO D 2 154 ? -72.204 -14.498 31.46   1   40.56  ? 324 PRO D CD  1 
ATOM   8199 N  N   . ALA D 2 155 ? -68.87  -12.271 33.133  1   45.67  ? 325 ALA D N   1 
ATOM   8200 C  CA  . ALA D 2 155 ? -67.554 -12.677 33.658  1   42.89  ? 325 ALA D CA  1 
ATOM   8201 C  C   . ALA D 2 155 ? -67.743 -13.76  34.711  1   43.46  ? 325 ALA D C   1 
ATOM   8202 O  O   . ALA D 2 155 ? -68.716 -13.684 35.48   1   44.1   ? 325 ALA D O   1 
ATOM   8203 C  CB  . ALA D 2 155 ? -66.84  -11.482 34.221  1   36.2   ? 325 ALA D CB  1 
ATOM   8204 N  N   . ASN D 2 156 ? -66.841 -14.73  34.735  1   41.15  ? 326 ASN D N   1 
ATOM   8205 C  CA  . ASN D 2 156 ? -66.883 -15.835 35.679  1   39.52  ? 326 ASN D CA  1 
ATOM   8206 C  C   . ASN D 2 156 ? -65.523 -15.887 36.366  1   41.89  ? 326 ASN D C   1 
ATOM   8207 O  O   . ASN D 2 156 ? -64.498 -16.097 35.714  1   43.34  ? 326 ASN D O   1 
ATOM   8208 C  CB  . ASN D 2 156 ? -67.162 -17.164 34.978  1   39.72  ? 326 ASN D CB  1 
ATOM   8209 C  CG  . ASN D 2 156 ? -67.41  -18.314 35.927  1   37.05  ? 326 ASN D CG  1 
ATOM   8210 O  OD1 . ASN D 2 156 ? -66.526 -18.702 36.7    1   36.94  ? 326 ASN D OD1 1 
ATOM   8211 N  ND2 . ASN D 2 156 ? -68.605 -18.881 35.863  1   33.5   ? 326 ASN D ND2 1 
ATOM   8212 N  N   . CYS D 2 157 ? -65.522 -15.667 37.683  1   41.01  ? 327 CYS D N   1 
ATOM   8213 C  CA  . CYS D 2 157 ? -64.286 -15.609 38.447  1   37.82  ? 327 CYS D CA  1 
ATOM   8214 C  C   . CYS D 2 157 ? -63.63  -16.992 38.528  1   33.52  ? 327 CYS D C   1 
ATOM   8215 O  O   . CYS D 2 157 ? -62.439 -17.089 38.791  1   31.68  ? 327 CYS D O   1 
ATOM   8216 C  CB  . CYS D 2 157 ? -64.575 -15.11  39.854  1   39.96  ? 327 CYS D CB  1 
ATOM   8217 S  SG  . CYS D 2 157 ? -65.579 -16.314 40.755  1   53.71  ? 327 CYS D SG  1 
ATOM   8218 N  N   . LYS D 2 158 ? -64.408 -18.063 38.325  1   33.89  ? 328 LYS D N   1 
ATOM   8219 C  CA  . LYS D 2 158 ? -63.885 -19.418 38.402  1   35.02  ? 328 LYS D CA  1 
ATOM   8220 C  C   . LYS D 2 158 ? -63.11  -19.722 37.117  1   34.57  ? 328 LYS D C   1 
ATOM   8221 O  O   . LYS D 2 158 ? -62.016 -20.292 37.163  1   33.98  ? 328 LYS D O   1 
ATOM   8222 C  CB  . LYS D 2 158 ? -65.035 -20.401 38.644  1   38.23  ? 328 LYS D CB  1 
ATOM   8223 C  CG  . LYS D 2 158 ? -64.814 -21.434 39.74   1   43.15  ? 328 LYS D CG  1 
ATOM   8224 C  CD  . LYS D 2 158 ? -65.406 -20.988 41.075  1   47.51  ? 328 LYS D CD  1 
ATOM   8225 C  CE  . LYS D 2 158 ? -65.649 -22.074 42.094  1   44.53  ? 328 LYS D CE  1 
ATOM   8226 N  NZ  . LYS D 2 158 ? -66.475 -23.174 41.593  1   38.95  ? 328 LYS D NZ  1 
ATOM   8227 N  N   . VAL D 2 159 ? -63.677 -19.319 35.97   1   33.4   ? 329 VAL D N   1 
ATOM   8228 C  CA  . VAL D 2 159 ? -62.964 -19.333 34.699  1   33.27  ? 329 VAL D CA  1 
ATOM   8229 C  C   . VAL D 2 159 ? -61.64  -18.561 34.829  1   33.98  ? 329 VAL D C   1 
ATOM   8230 O  O   . VAL D 2 159 ? -60.584 -19.08  34.483  1   36.32  ? 329 VAL D O   1 
ATOM   8231 C  CB  . VAL D 2 159 ? -63.848 -18.791 33.558  1   30.74  ? 329 VAL D CB  1 
ATOM   8232 C  CG1 . VAL D 2 159 ? -63.078 -18.623 32.255  1   30.76  ? 329 VAL D CG1 1 
ATOM   8233 C  CG2 . VAL D 2 159 ? -65.061 -19.67  33.323  1   30.71  ? 329 VAL D CG2 1 
ATOM   8234 N  N   . GLU D 2 160 ? -61.681 -17.332 35.36   1   34.12  ? 330 GLU D N   1 
ATOM   8235 C  CA  . GLU D 2 160 ? -60.492 -16.493 35.461  1   31.97  ? 330 GLU D CA  1 
ATOM   8236 C  C   . GLU D 2 160 ? -59.393 -17.195 36.26   1   31.24  ? 330 GLU D C   1 
ATOM   8237 O  O   . GLU D 2 160 ? -58.257 -17.288 35.792  1   30.78  ? 330 GLU D O   1 
ATOM   8238 C  CB  . GLU D 2 160 ? -60.839 -15.096 35.967  1   32.03  ? 330 GLU D CB  1 
ATOM   8239 C  CG  . GLU D 2 160 ? -61.707 -14.311 34.982  1   35.35  ? 330 GLU D CG  1 
ATOM   8240 C  CD  . GLU D 2 160 ? -62.105 -12.909 35.422  1   36.19  ? 330 GLU D CD  1 
ATOM   8241 O  OE1 . GLU D 2 160 ? -61.595 -12.486 36.483  1   36.47  ? 330 GLU D OE1 1 
ATOM   8242 O  OE2 . GLU D 2 160 ? -62.893 -12.243 34.701  1   34.59  ? 330 GLU D OE2 1 
ATOM   8243 N  N   . SER D 2 161 ? -59.753 -17.713 37.44   1   29.5   ? 331 SER D N   1 
ATOM   8244 C  CA  . SER D 2 161 ? -58.827 -18.438 38.291  1   29.64  ? 331 SER D CA  1 
ATOM   8245 C  C   . SER D 2 161 ? -58.267 -19.663 37.574  1   31.61  ? 331 SER D C   1 
ATOM   8246 O  O   . SER D 2 161 ? -57.078 -19.94  37.683  1   34.14  ? 331 SER D O   1 
ATOM   8247 C  CB  . SER D 2 161 ? -59.478 -18.837 39.589  1   31.7   ? 331 SER D CB  1 
ATOM   8248 O  OG  . SER D 2 161 ? -59.335 -17.837 40.585  1   33.73  ? 331 SER D OG  1 
ATOM   8249 N  N   . LEU D 2 162 ? -59.127 -20.421 36.879  1   30.44  ? 332 LEU D N   1 
ATOM   8250 C  CA  . LEU D 2 162 ? -58.703 -21.682 36.295  1   27.66  ? 332 LEU D CA  1 
ATOM   8251 C  C   . LEU D 2 162 ? -57.681 -21.411 35.186  1   29.3   ? 332 LEU D C   1 
ATOM   8252 O  O   . LEU D 2 162 ? -56.685 -22.135 35.059  1   29.58  ? 332 LEU D O   1 
ATOM   8253 C  CB  . LEU D 2 162 ? -59.911 -22.465 35.785  1   26.71  ? 332 LEU D CB  1 
ATOM   8254 C  CG  . LEU D 2 162 ? -59.649 -23.884 35.255  1   28.59  ? 332 LEU D CG  1 
ATOM   8255 C  CD1 . LEU D 2 162 ? -58.873 -24.753 36.233  1   29.07  ? 332 LEU D CD1 1 
ATOM   8256 C  CD2 . LEU D 2 162 ? -60.936 -24.607 34.885  1   27.4   ? 332 LEU D CD2 1 
ATOM   8257 N  N   . ALA D 2 163 ? -57.926 -20.357 34.389  1   26.7   ? 333 ALA D N   1 
ATOM   8258 C  CA  . ALA D 2 163 ? -57.03  -20.021 33.296  1   27.89  ? 333 ALA D CA  1 
ATOM   8259 C  C   . ALA D 2 163 ? -55.651 -19.659 33.855  1   30.96  ? 333 ALA D C   1 
ATOM   8260 O  O   . ALA D 2 163 ? -54.633 -20.203 33.393  1   29.22  ? 333 ALA D O   1 
ATOM   8261 C  CB  . ALA D 2 163 ? -57.627 -18.929 32.435  1   25.96  ? 333 ALA D CB  1 
ATOM   8262 N  N   . MET D 2 164 ? -55.651 -18.769 34.874  1   30.45  ? 334 MET D N   1 
ATOM   8263 C  CA  . MET D 2 164 ? -54.456 -18.354 35.591  1   30.6   ? 334 MET D CA  1 
ATOM   8264 C  C   . MET D 2 164 ? -53.676 -19.59  36.03   1   31.38  ? 334 MET D C   1 
ATOM   8265 O  O   . MET D 2 164 ? -52.475 -19.688 35.751  1   34.5   ? 334 MET D O   1 
ATOM   8266 C  CB  . MET D 2 164 ? -54.787 -17.504 36.823  1   32.89  ? 334 MET D CB  1 
ATOM   8267 C  CG  . MET D 2 164 ? -55.127 -16.042 36.524  1   39.88  ? 334 MET D CG  1 
ATOM   8268 S  SD  . MET D 2 164 ? -53.871 -15.087 35.635  1   46.82  ? 334 MET D SD  1 
ATOM   8269 C  CE  . MET D 2 164 ? -54.69  -13.489 35.66   1   49     ? 334 MET D CE  1 
ATOM   8270 N  N   . PHE D 2 165 ? -54.384 -20.527 36.68   1   28.09  ? 335 PHE D N   1 
ATOM   8271 C  CA  . PHE D 2 165 ? -53.786 -21.723 37.256  1   27.34  ? 335 PHE D CA  1 
ATOM   8272 C  C   . PHE D 2 165 ? -53.103 -22.59  36.202  1   27.5   ? 335 PHE D C   1 
ATOM   8273 O  O   . PHE D 2 165 ? -51.984 -23.044 36.421  1   26.68  ? 335 PHE D O   1 
ATOM   8274 C  CB  . PHE D 2 165 ? -54.868 -22.54  37.95   1   25.99  ? 335 PHE D CB  1 
ATOM   8275 C  CG  . PHE D 2 165 ? -54.463 -23.975 38.218  1   25.99  ? 335 PHE D CG  1 
ATOM   8276 C  CD1 . PHE D 2 165 ? -53.477 -24.277 39.147  1   25.14  ? 335 PHE D CD1 1 
ATOM   8277 C  CD2 . PHE D 2 165 ? -55.103 -25.022 37.558  1   27.31  ? 335 PHE D CD2 1 
ATOM   8278 C  CE1 . PHE D 2 165 ? -53.146 -25.597 39.414  1   25.83  ? 335 PHE D CE1 1 
ATOM   8279 C  CE2 . PHE D 2 165 ? -54.762 -26.345 37.827  1   26.16  ? 335 PHE D CE2 1 
ATOM   8280 C  CZ  . PHE D 2 165 ? -53.784 -26.63  38.755  1   24.85  ? 335 PHE D CZ  1 
ATOM   8281 N  N   . LEU D 2 166 ? -53.796 -22.828 35.08   1   28.84  ? 336 LEU D N   1 
ATOM   8282 C  CA  . LEU D 2 166 ? -53.268 -23.608 33.967  1   29.63  ? 336 LEU D CA  1 
ATOM   8283 C  C   . LEU D 2 166 ? -52.071 -22.876 33.372  1   30.99  ? 336 LEU D C   1 
ATOM   8284 O  O   . LEU D 2 166 ? -51.055 -23.489 33.045  1   34.84  ? 336 LEU D O   1 
ATOM   8285 C  CB  . LEU D 2 166 ? -54.332 -23.842 32.893  1   27.46  ? 336 LEU D CB  1 
ATOM   8286 C  CG  . LEU D 2 166 ? -55.557 -24.672 33.29   1   26.82  ? 336 LEU D CG  1 
ATOM   8287 C  CD1 . LEU D 2 166 ? -56.593 -24.626 32.176  1   28.55  ? 336 LEU D CD1 1 
ATOM   8288 C  CD2 . LEU D 2 166 ? -55.233 -26.112 33.648  1   23.67  ? 336 LEU D CD2 1 
ATOM   8289 N  N   . GLY D 2 167 ? -52.22  -21.556 33.212  1   30.06  ? 337 GLY D N   1 
ATOM   8290 C  CA  . GLY D 2 167 ? -51.162 -20.743 32.627  1   31.27  ? 337 GLY D CA  1 
ATOM   8291 C  C   . GLY D 2 167 ? -49.863 -20.854 33.423  1   30.2   ? 337 GLY D C   1 
ATOM   8292 O  O   . GLY D 2 167 ? -48.765 -20.812 32.867  1   29.78  ? 337 GLY D O   1 
ATOM   8293 N  N   . GLU D 2 168 ? -50.023 -20.984 34.742  1   30.73  ? 338 GLU D N   1 
ATOM   8294 C  CA  . GLU D 2 168 ? -48.914 -20.991 35.675  1   30.3   ? 338 GLU D CA  1 
ATOM   8295 C  C   . GLU D 2 168 ? -48.258 -22.373 35.633  1   31.64  ? 338 GLU D C   1 
ATOM   8296 O  O   . GLU D 2 168 ? -47.045 -22.501 35.796  1   32.42  ? 338 GLU D O   1 
ATOM   8297 C  CB  . GLU D 2 168 ? -49.482 -20.611 37.043  1   28.71  ? 338 GLU D CB  1 
ATOM   8298 C  CG  . GLU D 2 168 ? -48.715 -19.482 37.715  1   28.57  ? 338 GLU D CG  1 
ATOM   8299 C  CD  . GLU D 2 168 ? -49.215 -19.077 39.093  1   30.29  ? 338 GLU D CD  1 
ATOM   8300 O  OE1 . GLU D 2 168 ? -48.63  -19.557 40.091  1   29.82  ? 338 GLU D OE1 1 
ATOM   8301 O  OE2 . GLU D 2 168 ? -50.144 -18.25  39.182  1   29.83  ? 338 GLU D OE2 1 
ATOM   8302 N  N   . LEU D 2 169 ? -49.077 -23.408 35.419  1   28.89  ? 339 LEU D N   1 
ATOM   8303 C  CA  . LEU D 2 169 ? -48.572 -24.761 35.318  1   27.2   ? 339 LEU D CA  1 
ATOM   8304 C  C   . LEU D 2 169 ? -47.584 -24.825 34.162  1   26.56  ? 339 LEU D C   1 
ATOM   8305 O  O   . LEU D 2 169 ? -46.56  -25.482 34.276  1   28.2   ? 339 LEU D O   1 
ATOM   8306 C  CB  . LEU D 2 169 ? -49.713 -25.764 35.125  1   27.49  ? 339 LEU D CB  1 
ATOM   8307 C  CG  . LEU D 2 169 ? -50.543 -26.143 36.358  1   25.96  ? 339 LEU D CG  1 
ATOM   8308 C  CD1 . LEU D 2 169 ? -51.472 -27.302 36.03   1   25.24  ? 339 LEU D CD1 1 
ATOM   8309 C  CD2 . LEU D 2 169 ? -49.692 -26.492 37.56   1   24.48  ? 339 LEU D CD2 1 
ATOM   8310 N  N   . SER D 2 170 ? -47.893 -24.128 33.063  1   26.57  ? 340 SER D N   1 
ATOM   8311 C  CA  . SER D 2 170 ? -47.051 -24.139 31.877  1   27.21  ? 340 SER D CA  1 
ATOM   8312 C  C   . SER D 2 170 ? -45.662 -23.551 32.153  1   31.01  ? 340 SER D C   1 
ATOM   8313 O  O   . SER D 2 170 ? -44.711 -23.92  31.47   1   33.86  ? 340 SER D O   1 
ATOM   8314 C  CB  . SER D 2 170 ? -47.728 -23.457 30.717  1   25.74  ? 340 SER D CB  1 
ATOM   8315 O  OG  . SER D 2 170 ? -47.475 -22.059 30.701  1   24.69  ? 340 SER D OG  1 
ATOM   8316 N  N   . LEU D 2 171 ? -45.547 -22.639 33.141  1   31.19  ? 341 LEU D N   1 
ATOM   8317 C  CA  . LEU D 2 171 ? -44.278 -22.043 33.555  1   28.71  ? 341 LEU D CA  1 
ATOM   8318 C  C   . LEU D 2 171 ? -43.244 -23.104 33.936  1   28.92  ? 341 LEU D C   1 
ATOM   8319 O  O   . LEU D 2 171 ? -42.059 -22.932 33.64   1   28.12  ? 341 LEU D O   1 
ATOM   8320 C  CB  . LEU D 2 171 ? -44.474 -21.05  34.702  1   25.45  ? 341 LEU D CB  1 
ATOM   8321 C  CG  . LEU D 2 171 ? -45.292 -19.8   34.364  1   23.4   ? 341 LEU D CG  1 
ATOM   8322 C  CD1 . LEU D 2 171 ? -45.374 -18.884 35.563  1   24.53  ? 341 LEU D CD1 1 
ATOM   8323 C  CD2 . LEU D 2 171 ? -44.716 -19.03  33.172  1   21.35  ? 341 LEU D CD2 1 
ATOM   8324 N  N   . ILE D 2 172 ? -43.716 -24.191 34.57   1   27.21  ? 342 ILE D N   1 
ATOM   8325 C  CA  . ILE D 2 172 ? -42.893 -25.199 35.224  1   25.87  ? 342 ILE D CA  1 
ATOM   8326 C  C   . ILE D 2 172 ? -42.105 -26.038 34.208  1   26.63  ? 342 ILE D C   1 
ATOM   8327 O  O   . ILE D 2 172 ? -40.98  -26.451 34.501  1   25.91  ? 342 ILE D O   1 
ATOM   8328 C  CB  . ILE D 2 172 ? -43.781 -26.071 36.135  1   23.96  ? 342 ILE D CB  1 
ATOM   8329 C  CG1 . ILE D 2 172 ? -44.538 -25.247 37.171  1   23.27  ? 342 ILE D CG1 1 
ATOM   8330 C  CG2 . ILE D 2 172 ? -42.985 -27.201 36.779  1   24.41  ? 342 ILE D CG2 1 
ATOM   8331 C  CD1 . ILE D 2 172 ? -43.664 -24.62  38.236  1   25.37  ? 342 ILE D CD1 1 
ATOM   8332 N  N   . ASP D 2 173 ? -42.704 -26.297 33.032  1   24.76  ? 343 ASP D N   1 
ATOM   8333 C  CA  . ASP D 2 173 ? -42.223 -27.311 32.101  1   25.06  ? 343 ASP D CA  1 
ATOM   8334 C  C   . ASP D 2 173 ? -41.802 -26.715 30.761  1   25.75  ? 343 ASP D C   1 
ATOM   8335 O  O   . ASP D 2 173 ? -42.631 -26.525 29.865  1   25.12  ? 343 ASP D O   1 
ATOM   8336 C  CB  . ASP D 2 173 ? -43.315 -28.319 31.828  1   24.51  ? 343 ASP D CB  1 
ATOM   8337 C  CG  . ASP D 2 173 ? -43.722 -29.079 33.07   1   27.14  ? 343 ASP D CG  1 
ATOM   8338 O  OD1 . ASP D 2 173 ? -42.798 -29.542 33.803  1   24.37  ? 343 ASP D OD1 1 
ATOM   8339 O  OD2 . ASP D 2 173 ? -44.954 -29.19  33.273  1   30.57  ? 343 ASP D OD2 1 
ATOM   8340 N  N   . ALA D 2 174 ? -40.498 -26.459 30.623  1   24.73  ? 344 ALA D N   1 
ATOM   8341 C  CA  . ALA D 2 174 ? -39.962 -25.85  29.418  1   26.93  ? 344 ALA D CA  1 
ATOM   8342 C  C   . ALA D 2 174 ? -40.294 -26.716 28.202  1   27.33  ? 344 ALA D C   1 
ATOM   8343 O  O   . ALA D 2 174 ? -40.487 -26.21  27.1    1   26.4   ? 344 ALA D O   1 
ATOM   8344 C  CB  . ALA D 2 174 ? -38.468 -25.712 29.576  1   28.5   ? 344 ALA D CB  1 
ATOM   8345 N  N   . ASP D 2 175 ? -40.279 -28.034 28.413  1   27.13  ? 345 ASP D N   1 
ATOM   8346 C  CA  . ASP D 2 175 ? -40.78  -28.99  27.443  1   29.43  ? 345 ASP D CA  1 
ATOM   8347 C  C   . ASP D 2 175 ? -42.151 -29.463 27.923  1   28.18  ? 345 ASP D C   1 
ATOM   8348 O  O   . ASP D 2 175 ? -42.229 -30.206 28.895  1   27.02  ? 345 ASP D O   1 
ATOM   8349 C  CB  . ASP D 2 175 ? -39.834 -30.169 27.24   1   28.84  ? 345 ASP D CB  1 
ATOM   8350 C  CG  . ASP D 2 175 ? -40.467 -31.329 26.486  1   31.4   ? 345 ASP D CG  1 
ATOM   8351 O  OD1 . ASP D 2 175 ? -41.524 -31.106 25.867  1   34.64  ? 345 ASP D OD1 1 
ATOM   8352 O  OD2 . ASP D 2 175 ? -39.94  -32.455 26.559  1   30.87  ? 345 ASP D OD2 1 
ATOM   8353 N  N   . PRO D 2 176 ? -43.269 -29.149 27.221  1   29.43  ? 346 PRO D N   1 
ATOM   8354 C  CA  . PRO D 2 176 ? -43.22  -28.532 25.888  1   31.55  ? 346 PRO D CA  1 
ATOM   8355 C  C   . PRO D 2 176 ? -43.351 -27.026 25.651  1   30.82  ? 346 PRO D C   1 
ATOM   8356 O  O   . PRO D 2 176 ? -43.33  -26.62  24.496  1   33.33  ? 346 PRO D O   1 
ATOM   8357 C  CB  . PRO D 2 176 ? -44.437 -29.254 25.275  1   28.71  ? 346 PRO D CB  1 
ATOM   8358 C  CG  . PRO D 2 176 ? -45.454 -29.224 26.397  1   26.79  ? 346 PRO D CG  1 
ATOM   8359 C  CD  . PRO D 2 176 ? -44.642 -29.49  27.638  1   25.83  ? 346 PRO D CD  1 
ATOM   8360 N  N   . TYR D 2 177 ? -43.452 -26.219 26.714  1   28.01  ? 347 TYR D N   1 
ATOM   8361 C  CA  . TYR D 2 177 ? -44.109 -24.922 26.648  1   26.73  ? 347 TYR D CA  1 
ATOM   8362 C  C   . TYR D 2 177 ? -43.206 -23.809 26.121  1   28.8   ? 347 TYR D C   1 
ATOM   8363 O  O   . TYR D 2 177 ? -43.71  -22.737 25.784  1   33.63  ? 347 TYR D O   1 
ATOM   8364 C  CB  . TYR D 2 177 ? -44.817 -24.585 27.969  1   25.86  ? 347 TYR D CB  1 
ATOM   8365 C  CG  . TYR D 2 177 ? -45.965 -25.546 28.226  1   28.29  ? 347 TYR D CG  1 
ATOM   8366 C  CD1 . TYR D 2 177 ? -47.138 -25.473 27.482  1   28.38  ? 347 TYR D CD1 1 
ATOM   8367 C  CD2 . TYR D 2 177 ? -45.836 -26.594 29.13   1   31.31  ? 347 TYR D CD2 1 
ATOM   8368 C  CE1 . TYR D 2 177 ? -48.169 -26.382 27.664  1   28.82  ? 347 TYR D CE1 1 
ATOM   8369 C  CE2 . TYR D 2 177 ? -46.862 -27.51  29.317  1   30.99  ? 347 TYR D CE2 1 
ATOM   8370 C  CZ  . TYR D 2 177 ? -48.033 -27.41  28.583  1   28.76  ? 347 TYR D CZ  1 
ATOM   8371 O  OH  . TYR D 2 177 ? -49.046 -28.304 28.783  1   25.74  ? 347 TYR D OH  1 
ATOM   8372 N  N   . LEU D 2 178 ? -41.887 -24.02  26.058  1   29.61  ? 348 LEU D N   1 
ATOM   8373 C  CA  . LEU D 2 178 ? -41.013 -23.014 25.452  1   29.67  ? 348 LEU D CA  1 
ATOM   8374 C  C   . LEU D 2 178 ? -41.354 -22.809 23.978  1   29.34  ? 348 LEU D C   1 
ATOM   8375 O  O   . LEU D 2 178 ? -41.06  -21.756 23.419  1   30.74  ? 348 LEU D O   1 
ATOM   8376 C  CB  . LEU D 2 178 ? -39.528 -23.328 25.599  1   29.7   ? 348 LEU D CB  1 
ATOM   8377 C  CG  . LEU D 2 178 ? -38.889 -23.07  26.966  1   30.98  ? 348 LEU D CG  1 
ATOM   8378 C  CD1 . LEU D 2 178 ? -37.426 -23.476 26.878  1   32.13  ? 348 LEU D CD1 1 
ATOM   8379 C  CD2 . LEU D 2 178 ? -38.98  -21.62  27.391  1   28.91  ? 348 LEU D CD2 1 
ATOM   8380 N  N   . LYS D 2 179 ? -41.987 -23.809 23.354  1   30.08  ? 349 LYS D N   1 
ATOM   8381 C  CA  . LYS D 2 179 ? -42.248 -23.733 21.927  1   29.81  ? 349 LYS D CA  1 
ATOM   8382 C  C   . LYS D 2 179 ? -43.573 -23.026 21.656  1   31.06  ? 349 LYS D C   1 
ATOM   8383 O  O   . LYS D 2 179 ? -43.95  -22.909 20.499  1   35.05  ? 349 LYS D O   1 
ATOM   8384 C  CB  . LYS D 2 179 ? -42.197 -25.095 21.234  1   27.6   ? 349 LYS D CB  1 
ATOM   8385 C  CG  . LYS D 2 179 ? -43.402 -25.984 21.477  1   28.99  ? 349 LYS D CG  1 
ATOM   8386 C  CD  . LYS D 2 179 ? -43.264 -27.353 20.808  1   32.37  ? 349 LYS D CD  1 
ATOM   8387 C  CE  . LYS D 2 179 ? -43.707 -28.508 21.654  1   34.11  ? 349 LYS D CE  1 
ATOM   8388 N  NZ  . LYS D 2 179 ? -43.902 -29.735 20.878  1   34.63  ? 349 LYS D NZ  1 
ATOM   8389 N  N   . TYR D 2 180 ? -44.274 -22.569 22.705  1   31.54  ? 350 TYR D N   1 
ATOM   8390 C  CA  . TYR D 2 180 ? -45.53  -21.841 22.539  1   29.84  ? 350 TYR D CA  1 
ATOM   8391 C  C   . TYR D 2 180 ? -45.354 -20.411 23.043  1   30.1   ? 350 TYR D C   1 
ATOM   8392 O  O   . TYR D 2 180 ? -44.738 -20.208 24.086  1   33.36  ? 350 TYR D O   1 
ATOM   8393 C  CB  . TYR D 2 180 ? -46.656 -22.549 23.298  1   29.41  ? 350 TYR D CB  1 
ATOM   8394 C  CG  . TYR D 2 180 ? -46.971 -23.965 22.819  1   29.36  ? 350 TYR D CG  1 
ATOM   8395 C  CD1 . TYR D 2 180 ? -47.271 -24.212 21.483  1   27.88  ? 350 TYR D CD1 1 
ATOM   8396 C  CD2 . TYR D 2 180 ? -46.956 -25.054 23.697  1   26.52  ? 350 TYR D CD2 1 
ATOM   8397 C  CE1 . TYR D 2 180 ? -47.553 -25.491 21.033  1   29.48  ? 350 TYR D CE1 1 
ATOM   8398 C  CE2 . TYR D 2 180 ? -47.237 -26.336 23.257  1   24.89  ? 350 TYR D CE2 1 
ATOM   8399 C  CZ  . TYR D 2 180 ? -47.536 -26.553 21.921  1   27.25  ? 350 TYR D CZ  1 
ATOM   8400 O  OH  . TYR D 2 180 ? -47.822 -27.788 21.408  1   26.61  ? 350 TYR D OH  1 
ATOM   8401 N  N   . LEU D 2 181 ? -45.868 -19.439 22.273  1   27.88  ? 351 LEU D N   1 
ATOM   8402 C  CA  . LEU D 2 181 ? -45.88  -18.025 22.612  1   27.07  ? 351 LEU D CA  1 
ATOM   8403 C  C   . LEU D 2 181 ? -46.894 -17.764 23.723  1   28.13  ? 351 LEU D C   1 
ATOM   8404 O  O   . LEU D 2 181 ? -47.926 -18.438 23.793  1   27.97  ? 351 LEU D O   1 
ATOM   8405 C  CB  . LEU D 2 181 ? -46.257 -17.196 21.384  1   27.45  ? 351 LEU D CB  1 
ATOM   8406 C  CG  . LEU D 2 181 ? -45.207 -17.008 20.288  1   27.83  ? 351 LEU D CG  1 
ATOM   8407 C  CD1 . LEU D 2 181 ? -45.797 -16.121 19.199  1   29.04  ? 351 LEU D CD1 1 
ATOM   8408 C  CD2 . LEU D 2 181 ? -43.951 -16.377 20.84   1   26.71  ? 351 LEU D CD2 1 
ATOM   8409 N  N   . PRO D 2 182 ? -46.659 -16.754 24.597  1   26.96  ? 352 PRO D N   1 
ATOM   8410 C  CA  . PRO D 2 182 ? -47.564 -16.473 25.716  1   28     ? 352 PRO D CA  1 
ATOM   8411 C  C   . PRO D 2 182 ? -49.016 -16.347 25.263  1   27.48  ? 352 PRO D C   1 
ATOM   8412 O  O   . PRO D 2 182 ? -49.899 -16.959 25.86   1   29.66  ? 352 PRO D O   1 
ATOM   8413 C  CB  . PRO D 2 182 ? -47.035 -15.177 26.374  1   29.17  ? 352 PRO D CB  1 
ATOM   8414 C  CG  . PRO D 2 182 ? -45.59  -15.102 25.907  1   30.76  ? 352 PRO D CG  1 
ATOM   8415 C  CD  . PRO D 2 182 ? -45.497 -15.852 24.564  1   27.82  ? 352 PRO D CD  1 
ATOM   8416 N  N   . SER D 2 183 ? -49.245 -15.565 24.201  1   24.79  ? 353 SER D N   1 
ATOM   8417 C  CA  . SER D 2 183 ? -50.588 -15.313 23.709  1   24.34  ? 353 SER D CA  1 
ATOM   8418 C  C   . SER D 2 183 ? -51.295 -16.605 23.312  1   25.82  ? 353 SER D C   1 
ATOM   8419 O  O   . SER D 2 183 ? -52.521 -16.678 23.395  1   27.85  ? 353 SER D O   1 
ATOM   8420 C  CB  . SER D 2 183 ? -50.567 -14.363 22.559  1   26.49  ? 353 SER D CB  1 
ATOM   8421 O  OG  . SER D 2 183 ? -49.888 -14.931 21.448  1   27.96  ? 353 SER D OG  1 
ATOM   8422 N  N   . VAL D 2 184 ? -50.52  -17.579 22.817  1   25.04  ? 354 VAL D N   1 
ATOM   8423 C  CA  . VAL D 2 184 ? -51.022 -18.903 22.489  1   24.42  ? 354 VAL D CA  1 
ATOM   8424 C  C   . VAL D 2 184 ? -51.346 -19.654 23.782  1   24.45  ? 354 VAL D C   1 
ATOM   8425 O  O   . VAL D 2 184 ? -52.454 -20.171 23.934  1   25.59  ? 354 VAL D O   1 
ATOM   8426 C  CB  . VAL D 2 184 ? -50.073 -19.714 21.581  1   22.94  ? 354 VAL D CB  1 
ATOM   8427 C  CG1 . VAL D 2 184 ? -50.457 -21.191 21.541  1   21.43  ? 354 VAL D CG1 1 
ATOM   8428 C  CG2 . VAL D 2 184 ? -49.991 -19.13  20.181  1   20.95  ? 354 VAL D CG2 1 
ATOM   8429 N  N   . ILE D 2 185 ? -50.376 -19.731 24.702  1   23.48  ? 355 ILE D N   1 
ATOM   8430 C  CA  . ILE D 2 185 ? -50.604 -20.477 25.928  1   23.19  ? 355 ILE D CA  1 
ATOM   8431 C  C   . ILE D 2 185 ? -51.804 -19.895 26.657  1   25.08  ? 355 ILE D C   1 
ATOM   8432 O  O   . ILE D 2 185 ? -52.615 -20.655 27.165  1   25.8   ? 355 ILE D O   1 
ATOM   8433 C  CB  . ILE D 2 185 ? -49.363 -20.532 26.822  1   22.53  ? 355 ILE D CB  1 
ATOM   8434 C  CG1 . ILE D 2 185 ? -48.317 -21.457 26.216  1   21.7   ? 355 ILE D CG1 1 
ATOM   8435 C  CG2 . ILE D 2 185 ? -49.745 -20.967 28.239  1   24.04  ? 355 ILE D CG2 1 
ATOM   8436 C  CD1 . ILE D 2 185 ? -46.994 -21.424 26.939  1   19.77  ? 355 ILE D CD1 1 
ATOM   8437 N  N   . ALA D 2 186 ? -51.937 -18.564 26.644  1   26.75  ? 356 ALA D N   1 
ATOM   8438 C  CA  . ALA D 2 186 ? -53.028 -17.916 27.353  1   29.1   ? 356 ALA D CA  1 
ATOM   8439 C  C   . ALA D 2 186 ? -54.366 -18.286 26.722  1   32.06  ? 356 ALA D C   1 
ATOM   8440 O  O   . ALA D 2 186 ? -55.345 -18.542 27.429  1   33.81  ? 356 ALA D O   1 
ATOM   8441 C  CB  . ALA D 2 186 ? -52.839 -16.43  27.35   1   27.59  ? 356 ALA D CB  1 
ATOM   8442 N  N   . ALA D 2 187 ? -54.391 -18.31  25.384  1   31.53  ? 357 ALA D N   1 
ATOM   8443 C  CA  . ALA D 2 187 ? -55.591 -18.649 24.629  1   28.68  ? 357 ALA D CA  1 
ATOM   8444 C  C   . ALA D 2 187 ? -56.049 -20.072 24.937  1   27.35  ? 357 ALA D C   1 
ATOM   8445 O  O   . ALA D 2 187 ? -57.243 -20.318 25.046  1   27.75  ? 357 ALA D O   1 
ATOM   8446 C  CB  . ALA D 2 187 ? -55.349 -18.447 23.158  1   26.76  ? 357 ALA D CB  1 
ATOM   8447 N  N   . ALA D 2 188 ? -55.104 -21.003 25.092  1   27.67  ? 358 ALA D N   1 
ATOM   8448 C  CA  . ALA D 2 188 ? -55.456 -22.386 25.364  1   30.12  ? 358 ALA D CA  1 
ATOM   8449 C  C   . ALA D 2 188 ? -55.899 -22.556 26.819  1   28.81  ? 358 ALA D C   1 
ATOM   8450 O  O   . ALA D 2 188 ? -56.794 -23.342 27.119  1   28.74  ? 358 ALA D O   1 
ATOM   8451 C  CB  . ALA D 2 188 ? -54.297 -23.282 24.997  1   31.6   ? 358 ALA D CB  1 
ATOM   8452 N  N   . ALA D 2 189 ? -55.269 -21.807 27.719  1   28.06  ? 359 ALA D N   1 
ATOM   8453 C  CA  . ALA D 2 189 ? -55.615 -21.844 29.131  1   30.37  ? 359 ALA D CA  1 
ATOM   8454 C  C   . ALA D 2 189 ? -57.002 -21.236 29.337  1   30.11  ? 359 ALA D C   1 
ATOM   8455 O  O   . ALA D 2 189 ? -57.75  -21.649 30.224  1   31.02  ? 359 ALA D O   1 
ATOM   8456 C  CB  . ALA D 2 189 ? -54.553 -21.118 29.944  1   28.85  ? 359 ALA D CB  1 
ATOM   8457 N  N   . PHE D 2 190 ? -57.34  -20.256 28.499  1   27.77  ? 360 PHE D N   1 
ATOM   8458 C  CA  . PHE D 2 190 ? -58.644 -19.619 28.588  1   26.93  ? 360 PHE D CA  1 
ATOM   8459 C  C   . PHE D 2 190 ? -59.729 -20.505 27.971  1   26.28  ? 360 PHE D C   1 
ATOM   8460 O  O   . PHE D 2 190 ? -60.812 -20.606 28.53   1   25.04  ? 360 PHE D O   1 
ATOM   8461 C  CB  . PHE D 2 190 ? -58.627 -18.242 27.92   1   26.83  ? 360 PHE D CB  1 
ATOM   8462 C  CG  . PHE D 2 190 ? -59.976 -17.542 27.911  1   25.55  ? 360 PHE D CG  1 
ATOM   8463 C  CD1 . PHE D 2 190 ? -60.653 -17.285 29.097  1   25.41  ? 360 PHE D CD1 1 
ATOM   8464 C  CD2 . PHE D 2 190 ? -60.582 -17.192 26.708  1   25.49  ? 360 PHE D CD2 1 
ATOM   8465 C  CE1 . PHE D 2 190 ? -61.886 -16.658 29.074  1   26.16  ? 360 PHE D CE1 1 
ATOM   8466 C  CE2 . PHE D 2 190 ? -61.818 -16.576 26.687  1   24.73  ? 360 PHE D CE2 1 
ATOM   8467 C  CZ  . PHE D 2 190 ? -62.46  -16.301 27.87   1   26.74  ? 360 PHE D CZ  1 
ATOM   8468 N  N   . HIS D 2 191 ? -59.454 -21.125 26.812  1   26.64  ? 361 HIS D N   1 
ATOM   8469 C  CA  . HIS D 2 191 ? -60.406 -22.056 26.223  1   28.69  ? 361 HIS D CA  1 
ATOM   8470 C  C   . HIS D 2 191 ? -60.717 -23.177 27.218  1   29.97  ? 361 HIS D C   1 
ATOM   8471 O  O   . HIS D 2 191 ? -61.884 -23.505 27.459  1   29.03  ? 361 HIS D O   1 
ATOM   8472 C  CB  . HIS D 2 191 ? -59.917 -22.701 24.917  1   28.39  ? 361 HIS D CB  1 
ATOM   8473 C  CG  . HIS D 2 191 ? -60.787 -23.886 24.643  1   30.36  ? 361 HIS D CG  1 
ATOM   8474 N  ND1 . HIS D 2 191 ? -61.931 -23.835 23.873  1   31.57  ? 361 HIS D ND1 1 
ATOM   8475 C  CD2 . HIS D 2 191 ? -60.745 -25.127 25.147  1   30.38  ? 361 HIS D CD2 1 
ATOM   8476 C  CE1 . HIS D 2 191 ? -62.516 -25.024 23.861  1   31.07  ? 361 HIS D CE1 1 
ATOM   8477 N  NE2 . HIS D 2 191 ? -61.821 -25.815 24.649  1   32.35  ? 361 HIS D NE2 1 
ATOM   8478 N  N   . LEU D 2 192 ? -59.64  -23.763 27.763  1   30.28  ? 362 LEU D N   1 
ATOM   8479 C  CA  . LEU D 2 192 ? -59.697 -24.962 28.58   1   30.61  ? 362 LEU D CA  1 
ATOM   8480 C  C   . LEU D 2 192 ? -60.401 -24.683 29.905  1   31.84  ? 362 LEU D C   1 
ATOM   8481 O  O   . LEU D 2 192 ? -61.114 -25.546 30.419  1   28.58  ? 362 LEU D O   1 
ATOM   8482 C  CB  . LEU D 2 192 ? -58.25  -25.398 28.789  1   32.13  ? 362 LEU D CB  1 
ATOM   8483 C  CG  . LEU D 2 192 ? -58.017 -26.662 29.62   1   33.24  ? 362 LEU D CG  1 
ATOM   8484 C  CD1 . LEU D 2 192 ? -58.89  -27.815 29.143  1   31.47  ? 362 LEU D CD1 1 
ATOM   8485 C  CD2 . LEU D 2 192 ? -56.542 -27.034 29.566  1   32.85  ? 362 LEU D CD2 1 
ATOM   8486 N  N   . ALA D 2 193 ? -60.188 -23.474 30.445  1   34.04  ? 363 ALA D N   1 
ATOM   8487 C  CA  . ALA D 2 193 ? -60.778 -23.063 31.713  1   37.97  ? 363 ALA D CA  1 
ATOM   8488 C  C   . ALA D 2 193 ? -62.279 -22.855 31.545  1   39.76  ? 363 ALA D C   1 
ATOM   8489 O  O   . ALA D 2 193 ? -63.067 -23.226 32.415  1   39.84  ? 363 ALA D O   1 
ATOM   8490 C  CB  . ALA D 2 193 ? -60.131 -21.791 32.215  1   33.27  ? 363 ALA D CB  1 
ATOM   8491 N  N   . LEU D 2 194 ? -62.635 -22.236 30.414  1   40.33  ? 364 LEU D N   1 
ATOM   8492 C  CA  . LEU D 2 194 ? -63.995 -21.866 30.072  1   40.92  ? 364 LEU D CA  1 
ATOM   8493 C  C   . LEU D 2 194 ? -64.788 -23.126 29.719  1   41.13  ? 364 LEU D C   1 
ATOM   8494 O  O   . LEU D 2 194 ? -65.943 -23.253 30.125  1   46.73  ? 364 LEU D O   1 
ATOM   8495 C  CB  . LEU D 2 194 ? -63.874 -20.884 28.906  1   45.53  ? 364 LEU D CB  1 
ATOM   8496 C  CG  . LEU D 2 194 ? -65.126 -20.109 28.486  1   55.29  ? 364 LEU D CG  1 
ATOM   8497 C  CD1 . LEU D 2 194 ? -65.53  -19.089 29.537  1   60.34  ? 364 LEU D CD1 1 
ATOM   8498 C  CD2 . LEU D 2 194 ? -64.878 -19.413 27.152  1   58.84  ? 364 LEU D CD2 1 
ATOM   8499 N  N   . TYR D 2 195 ? -64.152 -24.068 29.004  1   36.34  ? 365 TYR D N   1 
ATOM   8500 C  CA  . TYR D 2 195 ? -64.747 -25.358 28.695  1   35.93  ? 365 TYR D CA  1 
ATOM   8501 C  C   . TYR D 2 195 ? -65.066 -26.12  29.979  1   35.72  ? 365 TYR D C   1 
ATOM   8502 O  O   . TYR D 2 195 ? -66.16  -26.667 30.111  1   39.38  ? 365 TYR D O   1 
ATOM   8503 C  CB  . TYR D 2 195 ? -63.865 -26.179 27.749  1   37.35  ? 365 TYR D CB  1 
ATOM   8504 C  CG  . TYR D 2 195 ? -64.472 -27.481 27.232  1   39.94  ? 365 TYR D CG  1 
ATOM   8505 C  CD1 . TYR D 2 195 ? -65.62  -27.474 26.441  1   41.34  ? 365 TYR D CD1 1 
ATOM   8506 C  CD2 . TYR D 2 195 ? -63.884 -28.718 27.489  1   39.94  ? 365 TYR D CD2 1 
ATOM   8507 C  CE1 . TYR D 2 195 ? -66.173 -28.648 25.947  1   42.32  ? 365 TYR D CE1 1 
ATOM   8508 C  CE2 . TYR D 2 195 ? -64.418 -29.899 26.984  1   40.66  ? 365 TYR D CE2 1 
ATOM   8509 C  CZ  . TYR D 2 195 ? -65.571 -29.869 26.21   1   42.61  ? 365 TYR D CZ  1 
ATOM   8510 O  OH  . TYR D 2 195 ? -66.151 -31.005 25.696  1   41.51  ? 365 TYR D OH  1 
ATOM   8511 N  N   . THR D 2 196 ? -64.121 -26.128 30.927  1   32.82  ? 366 THR D N   1 
ATOM   8512 C  CA  . THR D 2 196 ? -64.194 -26.954 32.128  1   33.37  ? 366 THR D CA  1 
ATOM   8513 C  C   . THR D 2 196 ? -65.326 -26.503 33.06   1   31.96  ? 366 THR D C   1 
ATOM   8514 O  O   . THR D 2 196 ? -66.042 -27.324 33.64   1   32.32  ? 366 THR D O   1 
ATOM   8515 C  CB  . THR D 2 196 ? -62.835 -26.968 32.834  1   34.55  ? 366 THR D CB  1 
ATOM   8516 O  OG1 . THR D 2 196 ? -61.849 -27.425 31.908  1   34.31  ? 366 THR D OG1 1 
ATOM   8517 C  CG2 . THR D 2 196 ? -62.822 -27.822 34.091  1   32.31  ? 366 THR D CG2 1 
ATOM   8518 N  N   . VAL D 2 197 ? -65.496 -25.187 33.191  1   30.31  ? 367 VAL D N   1 
ATOM   8519 C  CA  . VAL D 2 197 ? -66.42  -24.657 34.177  1   29.7   ? 367 VAL D CA  1 
ATOM   8520 C  C   . VAL D 2 197 ? -67.813 -24.514 33.565  1   28.31  ? 367 VAL D C   1 
ATOM   8521 O  O   . VAL D 2 197 ? -68.804 -24.83  34.22   1   26.04  ? 367 VAL D O   1 
ATOM   8522 C  CB  . VAL D 2 197 ? -65.907 -23.315 34.736  1   30.34  ? 367 VAL D CB  1 
ATOM   8523 C  CG1 . VAL D 2 197 ? -66.937 -22.633 35.624  1   31.88  ? 367 VAL D CG1 1 
ATOM   8524 C  CG2 . VAL D 2 197 ? -64.597 -23.466 35.492  1   31.87  ? 367 VAL D CG2 1 
ATOM   8525 N  N   . THR D 2 198 ? -67.876 -24.012 32.321  1   28.32  ? 368 THR D N   1 
ATOM   8526 C  CA  . THR D 2 198 ? -69.128 -23.56  31.721  1   27.53  ? 368 THR D CA  1 
ATOM   8527 C  C   . THR D 2 198 ? -69.61  -24.509 30.619  1   26.91  ? 368 THR D C   1 
ATOM   8528 O  O   . THR D 2 198 ? -70.812 -24.617 30.4    1   26.4   ? 368 THR D O   1 
ATOM   8529 C  CB  . THR D 2 198 ? -69.028 -22.117 31.214  1   27.19  ? 368 THR D CB  1 
ATOM   8530 O  OG1 . THR D 2 198 ? -68.293 -22.102 29.992  1   27.73  ? 368 THR D OG1 1 
ATOM   8531 C  CG2 . THR D 2 198 ? -68.438 -21.168 32.241  1   25.93  ? 368 THR D CG2 1 
ATOM   8532 N  N   . GLY D 2 199 ? -68.677 -25.167 29.917  1   27.16  ? 369 GLY D N   1 
ATOM   8533 C  CA  . GLY D 2 199 ? -69.007 -26.045 28.806  1   27.92  ? 369 GLY D CA  1 
ATOM   8534 C  C   . GLY D 2 199 ? -68.77  -25.387 27.447  1   29.78  ? 369 GLY D C   1 
ATOM   8535 O  O   . GLY D 2 199 ? -68.783 -26.065 26.425  1   29.85  ? 369 GLY D O   1 
ATOM   8536 N  N   . GLN D 2 200 ? -68.559 -24.066 27.432  1   32.09  ? 370 GLN D N   1 
ATOM   8537 C  CA  . GLN D 2 200 ? -68.464 -23.342 26.173  1   36.11  ? 370 GLN D CA  1 
ATOM   8538 C  C   . GLN D 2 200 ? -67.007 -23.271 25.73   1   35.64  ? 370 GLN D C   1 
ATOM   8539 O  O   . GLN D 2 200 ? -66.097 -23.627 26.479  1   36.17  ? 370 GLN D O   1 
ATOM   8540 C  CB  . GLN D 2 200 ? -68.885 -21.878 26.261  1   42.19  ? 370 GLN D CB  1 
ATOM   8541 C  CG  . GLN D 2 200 ? -70.251 -21.601 26.871  1   48.81  ? 370 GLN D CG  1 
ATOM   8542 C  CD  . GLN D 2 200 ? -70.235 -20.241 27.53   1   54.16  ? 370 GLN D CD  1 
ATOM   8543 O  OE1 . GLN D 2 200 ? -69.895 -19.225 26.911  1   50.57  ? 370 GLN D OE1 1 
ATOM   8544 N  NE2 . GLN D 2 200 ? -70.519 -20.222 28.823  1   59.75  ? 370 GLN D NE2 1 
ATOM   8545 N  N   . SER D 2 201 ? -66.813 -22.752 24.511  1   33.93  ? 371 SER D N   1 
ATOM   8546 C  CA  . SER D 2 201 ? -65.526 -22.782 23.84   1   34.65  ? 371 SER D CA  1 
ATOM   8547 C  C   . SER D 2 201 ? -64.997 -21.368 23.603  1   35.75  ? 371 SER D C   1 
ATOM   8548 O  O   . SER D 2 201 ? -65.724 -20.379 23.725  1   36.5   ? 371 SER D O   1 
ATOM   8549 C  CB  . SER D 2 201 ? -65.614 -23.559 22.556  1   34.48  ? 371 SER D CB  1 
ATOM   8550 O  OG  . SER D 2 201 ? -65.983 -24.901 22.835  1   38.15  ? 371 SER D OG  1 
ATOM   8551 N  N   . TRP D 2 202 ? -63.697 -21.305 23.303  1   32.3   ? 372 TRP D N   1 
ATOM   8552 C  CA  . TRP D 2 202 ? -63.048 -20.155 22.698  1   32.5   ? 372 TRP D CA  1 
ATOM   8553 C  C   . TRP D 2 202 ? -64.062 -19.349 21.88   1   33.37  ? 372 TRP D C   1 
ATOM   8554 O  O   . TRP D 2 202 ? -64.638 -19.862 20.913  1   35.1   ? 372 TRP D O   1 
ATOM   8555 C  CB  . TRP D 2 202 ? -61.874 -20.68  21.854  1   29.92  ? 372 TRP D CB  1 
ATOM   8556 C  CG  . TRP D 2 202 ? -60.983 -19.635 21.251  1   28.48  ? 372 TRP D CG  1 
ATOM   8557 C  CD1 . TRP D 2 202 ? -60.851 -19.341 19.925  1   28.31  ? 372 TRP D CD1 1 
ATOM   8558 C  CD2 . TRP D 2 202 ? -60.102 -18.742 21.963  1   29.75  ? 372 TRP D CD2 1 
ATOM   8559 N  NE1 . TRP D 2 202 ? -59.939 -18.334 19.754  1   30.47  ? 372 TRP D NE1 1 
ATOM   8560 C  CE2 . TRP D 2 202 ? -59.468 -17.938 20.983  1   30.16  ? 372 TRP D CE2 1 
ATOM   8561 C  CE3 . TRP D 2 202 ? -59.799 -18.535 23.316  1   27.88  ? 372 TRP D CE3 1 
ATOM   8562 C  CZ2 . TRP D 2 202 ? -58.548 -16.945 21.321  1   27.63  ? 372 TRP D CZ2 1 
ATOM   8563 C  CZ3 . TRP D 2 202 ? -58.881 -17.562 23.643  1   26.81  ? 372 TRP D CZ3 1 
ATOM   8564 C  CH2 . TRP D 2 202 ? -58.275 -16.779 22.66   1   27.6   ? 372 TRP D CH2 1 
ATOM   8565 N  N   . PRO D 2 203 ? -64.356 -18.081 22.271  1   32.7   ? 373 PRO D N   1 
ATOM   8566 C  CA  . PRO D 2 203 ? -65.376 -17.274 21.589  1   31.81  ? 373 PRO D CA  1 
ATOM   8567 C  C   . PRO D 2 203 ? -64.988 -16.65  20.253  1   31.01  ? 373 PRO D C   1 
ATOM   8568 O  O   . PRO D 2 203 ? -63.81  -16.421 19.981  1   30.42  ? 373 PRO D O   1 
ATOM   8569 C  CB  . PRO D 2 203 ? -65.737 -16.211 22.642  1   31.76  ? 373 PRO D CB  1 
ATOM   8570 C  CG  . PRO D 2 203 ? -64.465 -16.033 23.435  1   32.1   ? 373 PRO D CG  1 
ATOM   8571 C  CD  . PRO D 2 203 ? -63.783 -17.391 23.44   1   32.05  ? 373 PRO D CD  1 
ATOM   8572 N  N   . GLU D 2 204 ? -66.016 -16.34  19.456  1   32.45  ? 374 GLU D N   1 
ATOM   8573 C  CA  . GLU D 2 204 ? -65.868 -15.793 18.113  1   34.9   ? 374 GLU D CA  1 
ATOM   8574 C  C   . GLU D 2 204 ? -65.184 -14.42  18.158  1   33.54  ? 374 GLU D C   1 
ATOM   8575 O  O   . GLU D 2 204 ? -64.465 -14.047 17.228  1   32.17  ? 374 GLU D O   1 
ATOM   8576 C  CB  . GLU D 2 204 ? -67.242 -15.816 17.434  1   35.3   ? 374 GLU D CB  1 
ATOM   8577 C  CG  . GLU D 2 204 ? -67.301 -15.142 16.064  1   37.88  ? 374 GLU D CG  1 
ATOM   8578 C  CD  . GLU D 2 204 ? -66.374 -15.648 14.967  1   39.61  ? 374 GLU D CD  1 
ATOM   8579 O  OE1 . GLU D 2 204 ? -65.685 -16.676 15.156  1   36.36  ? 374 GLU D OE1 1 
ATOM   8580 O  OE2 . GLU D 2 204 ? -66.35  -14.993 13.899  1   41.98  ? 374 GLU D OE2 1 
ATOM   8581 N  N   . SER D 2 205 ? -65.424 -13.675 19.248  1   31.99  ? 375 SER D N   1 
ATOM   8582 C  CA  . SER D 2 205 ? -64.894 -12.331 19.44   1   28.78  ? 375 SER D CA  1 
ATOM   8583 C  C   . SER D 2 205 ? -63.371 -12.371 19.558  1   28.57  ? 375 SER D C   1 
ATOM   8584 O  O   . SER D 2 205 ? -62.68  -11.452 19.116  1   28.67  ? 375 SER D O   1 
ATOM   8585 C  CB  . SER D 2 205 ? -65.528 -11.664 20.636  1   25.93  ? 375 SER D CB  1 
ATOM   8586 O  OG  . SER D 2 205 ? -65.125 -12.304 21.839  1   26.25  ? 375 SER D OG  1 
ATOM   8587 N  N   . LEU D 2 206 ? -62.866 -13.448 20.167  1   27.8   ? 376 LEU D N   1 
ATOM   8588 C  CA  . LEU D 2 206 ? -61.443 -13.616 20.397  1   27.27  ? 376 LEU D CA  1 
ATOM   8589 C  C   . LEU D 2 206 ? -60.791 -14.292 19.201  1   28.1   ? 376 LEU D C   1 
ATOM   8590 O  O   . LEU D 2 206 ? -59.577 -14.185 19.032  1   31.44  ? 376 LEU D O   1 
ATOM   8591 C  CB  . LEU D 2 206 ? -61.186 -14.426 21.664  1   27.66  ? 376 LEU D CB  1 
ATOM   8592 C  CG  . LEU D 2 206 ? -61.331 -13.672 22.987  1   25.85  ? 376 LEU D CG  1 
ATOM   8593 C  CD1 . LEU D 2 206 ? -60.957 -14.581 24.142  1   25.52  ? 376 LEU D CD1 1 
ATOM   8594 C  CD2 . LEU D 2 206 ? -60.486 -12.423 22.976  1   24.05  ? 376 LEU D CD2 1 
ATOM   8595 N  N   . VAL D 2 207 ? -61.581 -15.015 18.406  1   24.3   ? 377 VAL D N   1 
ATOM   8596 C  CA  . VAL D 2 207 ? -61.088 -15.41  17.102  1   23.58  ? 377 VAL D CA  1 
ATOM   8597 C  C   . VAL D 2 207 ? -60.782 -14.139 16.31   1   24.79  ? 377 VAL D C   1 
ATOM   8598 O  O   . VAL D 2 207 ? -59.714 -14.034 15.704  1   24.83  ? 377 VAL D O   1 
ATOM   8599 C  CB  . VAL D 2 207 ? -62.055 -16.364 16.362  1   22.4   ? 377 VAL D CB  1 
ATOM   8600 C  CG1 . VAL D 2 207 ? -61.73  -16.509 14.877  1   19.71  ? 377 VAL D CG1 1 
ATOM   8601 C  CG2 . VAL D 2 207 ? -62.096 -17.73  17.033  1   20.68  ? 377 VAL D CG2 1 
ATOM   8602 N  N   . GLN D 2 208 ? -61.721 -13.18  16.333  1   26.63  ? 378 GLN D N   1 
ATOM   8603 C  CA  . GLN D 2 208 ? -61.572 -11.916 15.622  1   28.55  ? 378 GLN D CA  1 
ATOM   8604 C  C   . GLN D 2 208 ? -60.381 -11.137 16.174  1   28.98  ? 378 GLN D C   1 
ATOM   8605 O  O   . GLN D 2 208 ? -59.58  -10.621 15.398  1   29.68  ? 378 GLN D O   1 
ATOM   8606 C  CB  . GLN D 2 208 ? -62.857 -11.087 15.643  1   31     ? 378 GLN D CB  1 
ATOM   8607 C  CG  . GLN D 2 208 ? -63.966 -11.647 14.759  1   33.94  ? 378 GLN D CG  1 
ATOM   8608 C  CD  . GLN D 2 208 ? -63.519 -11.789 13.321  1   39.21  ? 378 GLN D CD  1 
ATOM   8609 O  OE1 . GLN D 2 208 ? -63.345 -12.901 12.805  1   40.86  ? 378 GLN D OE1 1 
ATOM   8610 N  NE2 . GLN D 2 208 ? -63.276 -10.655 12.675  1   41.31  ? 378 GLN D NE2 1 
ATOM   8611 N  N   . LYS D 2 209 ? -60.259 -11.082 17.509  1   29.33  ? 379 LYS D N   1 
ATOM   8612 C  CA  . LYS D 2 209 ? -59.213 -10.304 18.152  1   29.33  ? 379 LYS D CA  1 
ATOM   8613 C  C   . LYS D 2 209 ? -57.836 -10.881 17.835  1   29.74  ? 379 LYS D C   1 
ATOM   8614 O  O   . LYS D 2 209 ? -56.936 -10.134 17.47   1   29.02  ? 379 LYS D O   1 
ATOM   8615 C  CB  . LYS D 2 209 ? -59.398 -10.231 19.672  1   30.9   ? 379 LYS D CB  1 
ATOM   8616 C  CG  . LYS D 2 209 ? -58.476 -9.248  20.413  1   29.86  ? 379 LYS D CG  1 
ATOM   8617 C  CD  . LYS D 2 209 ? -58.577 -9.346  21.934  1   29.43  ? 379 LYS D CD  1 
ATOM   8618 C  CE  . LYS D 2 209 ? -57.669 -8.468  22.721  1   26.8   ? 379 LYS D CE  1 
ATOM   8619 N  NZ  . LYS D 2 209 ? -58.052 -7.066  22.586  1   29.02  ? 379 LYS D NZ  1 
ATOM   8620 N  N   . THR D 2 210 ? -57.688 -12.207 17.98   1   30.16  ? 380 THR D N   1 
ATOM   8621 C  CA  . THR D 2 210 ? -56.382 -12.856 18.036  1   31.44  ? 380 THR D CA  1 
ATOM   8622 C  C   . THR D 2 210 ? -55.987 -13.485 16.695  1   31.87  ? 380 THR D C   1 
ATOM   8623 O  O   . THR D 2 210 ? -54.821 -13.83  16.484  1   33.09  ? 380 THR D O   1 
ATOM   8624 C  CB  . THR D 2 210 ? -56.361 -13.925 19.133  1   32.59  ? 380 THR D CB  1 
ATOM   8625 O  OG1 . THR D 2 210 ? -57.268 -14.95  18.732  1   33.78  ? 380 THR D OG1 1 
ATOM   8626 C  CG2 . THR D 2 210 ? -56.709 -13.397 20.514  1   31.89  ? 380 THR D CG2 1 
ATOM   8627 N  N   . GLY D 2 211 ? -56.962 -13.71  15.808  1   30.89  ? 381 GLY D N   1 
ATOM   8628 C  CA  . GLY D 2 211 ? -56.712 -14.527 14.631  1   28.59  ? 381 GLY D CA  1 
ATOM   8629 C  C   . GLY D 2 211 ? -56.481 -16.003 14.974  1   29.87  ? 381 GLY D C   1 
ATOM   8630 O  O   . GLY D 2 211 ? -56.177 -16.792 14.082  1   31.3   ? 381 GLY D O   1 
ATOM   8631 N  N   . TYR D 2 212 ? -56.636 -16.396 16.249  1   29.14  ? 382 TYR D N   1 
ATOM   8632 C  CA  . TYR D 2 212 ? -56.456 -17.795 16.622  1   30.93  ? 382 TYR D CA  1 
ATOM   8633 C  C   . TYR D 2 212 ? -57.794 -18.524 16.531  1   30.12  ? 382 TYR D C   1 
ATOM   8634 O  O   . TYR D 2 212 ? -58.799 -18.016 17.02   1   29.78  ? 382 TYR D O   1 
ATOM   8635 C  CB  . TYR D 2 212 ? -55.867 -18.038 18.02   1   31.74  ? 382 TYR D CB  1 
ATOM   8636 C  CG  . TYR D 2 212 ? -54.534 -17.372 18.314  1   31.2   ? 382 TYR D CG  1 
ATOM   8637 C  CD1 . TYR D 2 212 ? -53.573 -17.207 17.318  1   31.09  ? 382 TYR D CD1 1 
ATOM   8638 C  CD2 . TYR D 2 212 ? -54.251 -16.888 19.586  1   30.18  ? 382 TYR D CD2 1 
ATOM   8639 C  CE1 . TYR D 2 212 ? -52.372 -16.567 17.582  1   30.69  ? 382 TYR D CE1 1 
ATOM   8640 C  CE2 . TYR D 2 212 ? -53.053 -16.247 19.862  1   29.94  ? 382 TYR D CE2 1 
ATOM   8641 C  CZ  . TYR D 2 212 ? -52.113 -16.091 18.858  1   30.35  ? 382 TYR D CZ  1 
ATOM   8642 O  OH  . TYR D 2 212 ? -50.93  -15.484 19.141  1   29.06  ? 382 TYR D OH  1 
ATOM   8643 N  N   . THR D 2 213 ? -57.774 -19.723 15.932  1   28.76  ? 383 THR D N   1 
ATOM   8644 C  CA  . THR D 2 213 ? -58.914 -20.626 15.952  1   30.16  ? 383 THR D CA  1 
ATOM   8645 C  C   . THR D 2 213 ? -58.561 -21.835 16.809  1   31.02  ? 383 THR D C   1 
ATOM   8646 O  O   . THR D 2 213 ? -57.391 -22.078 17.113  1   30.34  ? 383 THR D O   1 
ATOM   8647 C  CB  . THR D 2 213 ? -59.353 -21.039 14.545  1   29.78  ? 383 THR D CB  1 
ATOM   8648 O  OG1 . THR D 2 213 ? -58.411 -21.939 13.966  1   31.34  ? 383 THR D OG1 1 
ATOM   8649 C  CG2 . THR D 2 213 ? -59.516 -19.847 13.621  1   30.03  ? 383 THR D CG2 1 
ATOM   8650 N  N   . LEU D 2 214 ? -59.597 -22.597 17.171  1   31.65  ? 384 LEU D N   1 
ATOM   8651 C  CA  . LEU D 2 214 ? -59.395 -23.83  17.905  1   31.5   ? 384 LEU D CA  1 
ATOM   8652 C  C   . LEU D 2 214 ? -58.475 -24.755 17.116  1   30.44  ? 384 LEU D C   1 
ATOM   8653 O  O   . LEU D 2 214 ? -57.66  -25.455 17.703  1   29.47  ? 384 LEU D O   1 
ATOM   8654 C  CB  . LEU D 2 214 ? -60.748 -24.452 18.232  1   30.5   ? 384 LEU D CB  1 
ATOM   8655 C  CG  . LEU D 2 214 ? -61.47  -23.792 19.405  1   29.65  ? 384 LEU D CG  1 
ATOM   8656 C  CD1 . LEU D 2 214 ? -62.939 -24.128 19.378  1   32.05  ? 384 LEU D CD1 1 
ATOM   8657 C  CD2 . LEU D 2 214 ? -60.839 -24.263 20.698  1   29.79  ? 384 LEU D CD2 1 
ATOM   8658 N  N   . GLU D 2 215 ? -58.551 -24.69  15.784  1   31.17  ? 385 GLU D N   1 
ATOM   8659 C  CA  . GLU D 2 215 ? -57.608 -25.422 14.952  1   33.3   ? 385 GLU D CA  1 
ATOM   8660 C  C   . GLU D 2 215 ? -56.17  -25.019 15.316  1   31.62  ? 385 GLU D C   1 
ATOM   8661 O  O   . GLU D 2 215 ? -55.344 -25.86  15.662  1   29     ? 385 GLU D O   1 
ATOM   8662 C  CB  . GLU D 2 215 ? -57.973 -25.326 13.467  1   34.02  ? 385 GLU D CB  1 
ATOM   8663 C  CG  . GLU D 2 215 ? -57.266 -26.385 12.627  1   39.82  ? 385 GLU D CG  1 
ATOM   8664 C  CD  . GLU D 2 215 ? -57.365 -26.206 11.12   1   50.24  ? 385 GLU D CD  1 
ATOM   8665 O  OE1 . GLU D 2 215 ? -58.452 -26.424 10.538  1   51.43  ? 385 GLU D OE1 1 
ATOM   8666 O  OE2 . GLU D 2 215 ? -56.334 -25.834 10.52   1   55.62  ? 385 GLU D OE2 1 
ATOM   8667 N  N   . THR D 2 216 ? -55.854 -23.724 15.259  1   31.34  ? 386 THR D N   1 
ATOM   8668 C  CA  . THR D 2 216 ? -54.485 -23.303 15.517  1   34.07  ? 386 THR D CA  1 
ATOM   8669 C  C   . THR D 2 216 ? -54.097 -23.55  16.979  1   31.68  ? 386 THR D C   1 
ATOM   8670 O  O   . THR D 2 216 ? -52.917 -23.705 17.284  1   29.2   ? 386 THR D O   1 
ATOM   8671 C  CB  . THR D 2 216 ? -54.263 -21.855 15.075  1   37.24  ? 386 THR D CB  1 
ATOM   8672 O  OG1 . THR D 2 216 ? -55.177 -21.098 15.861  1   39.13  ? 386 THR D OG1 1 
ATOM   8673 C  CG2 . THR D 2 216 ? -54.5   -21.643 13.584  1   35.07  ? 386 THR D CG2 1 
ATOM   8674 N  N   . LEU D 2 217 ? -55.091 -23.632 17.873  1   29.96  ? 387 LEU D N   1 
ATOM   8675 C  CA  . LEU D 2 217 ? -54.824 -23.798 19.295  1   27.08  ? 387 LEU D CA  1 
ATOM   8676 C  C   . LEU D 2 217 ? -54.666 -25.264 19.679  1   26.98  ? 387 LEU D C   1 
ATOM   8677 O  O   . LEU D 2 217 ? -54.328 -25.547 20.819  1   28.37  ? 387 LEU D O   1 
ATOM   8678 C  CB  . LEU D 2 217 ? -55.949 -23.174 20.114  1   25.32  ? 387 LEU D CB  1 
ATOM   8679 C  CG  . LEU D 2 217 ? -56.011 -21.646 20.136  1   24.04  ? 387 LEU D CG  1 
ATOM   8680 C  CD1 . LEU D 2 217 ? -57.022 -21.185 21.177  1   24.22  ? 387 LEU D CD1 1 
ATOM   8681 C  CD2 . LEU D 2 217 ? -54.652 -21.015 20.379  1   22.97  ? 387 LEU D CD2 1 
ATOM   8682 N  N   . LYS D 2 218 ? -54.956 -26.195 18.766  1   28.17  ? 388 LYS D N   1 
ATOM   8683 C  CA  . LYS D 2 218 ? -55.074 -27.595 19.156  1   30.59  ? 388 LYS D CA  1 
ATOM   8684 C  C   . LYS D 2 218 ? -53.755 -28.121 19.731  1   31.18  ? 388 LYS D C   1 
ATOM   8685 O  O   . LYS D 2 218 ? -53.758 -28.723 20.813  1   32.47  ? 388 LYS D O   1 
ATOM   8686 C  CB  . LYS D 2 218 ? -55.564 -28.494 18.014  1   33.03  ? 388 LYS D CB  1 
ATOM   8687 C  CG  . LYS D 2 218 ? -56.054 -29.88  18.437  1   36.07  ? 388 LYS D CG  1 
ATOM   8688 C  CD  . LYS D 2 218 ? -56.516 -30.799 17.315  1   39.09  ? 388 LYS D CD  1 
ATOM   8689 C  CE  . LYS D 2 218 ? -55.413 -31.5   16.568  1   42.41  ? 388 LYS D CE  1 
ATOM   8690 N  NZ  . LYS D 2 218 ? -55.907 -32.637 15.777  1   38.79  ? 388 LYS D NZ  1 
ATOM   8691 N  N   . PRO D 2 219 ? -52.601 -27.952 19.028  1   28.24  ? 389 PRO D N   1 
ATOM   8692 C  CA  . PRO D 2 219 ? -51.347 -28.544 19.488  1   27.95  ? 389 PRO D CA  1 
ATOM   8693 C  C   . PRO D 2 219 ? -51.088 -28.164 20.944  1   30.07  ? 389 PRO D C   1 
ATOM   8694 O  O   . PRO D 2 219 ? -50.818 -29.033 21.774  1   30.05  ? 389 PRO D O   1 
ATOM   8695 C  CB  . PRO D 2 219 ? -50.275 -28.027 18.498  1   27.22  ? 389 PRO D CB  1 
ATOM   8696 C  CG  . PRO D 2 219 ? -51.055 -27.628 17.26   1   25.52  ? 389 PRO D CG  1 
ATOM   8697 C  CD  . PRO D 2 219 ? -52.448 -27.239 17.744  1   26.79  ? 389 PRO D CD  1 
ATOM   8698 N  N   . CYS D 2 220 ? -51.214 -26.86  21.236  1   32.72  ? 390 CYS D N   1 
ATOM   8699 C  CA  . CYS D 2 220 ? -51.046 -26.305 22.571  1   33.16  ? 390 CYS D CA  1 
ATOM   8700 C  C   . CYS D 2 220 ? -52.109 -26.849 23.527  1   33.52  ? 390 CYS D C   1 
ATOM   8701 O  O   . CYS D 2 220 ? -51.789 -27.239 24.651  1   31.8   ? 390 CYS D O   1 
ATOM   8702 C  CB  . CYS D 2 220 ? -51.092 -24.784 22.532  1   34.21  ? 390 CYS D CB  1 
ATOM   8703 S  SG  . CYS D 2 220 ? -50.556 -24.003 24.077  1   40.33  ? 390 CYS D SG  1 
ATOM   8704 N  N   . LEU D 2 221 ? -53.37  -26.883 23.07   1   33.93  ? 391 LEU D N   1 
ATOM   8705 C  CA  . LEU D 2 221 ? -54.482 -27.365 23.875  1   33.13  ? 391 LEU D CA  1 
ATOM   8706 C  C   . LEU D 2 221 ? -54.231 -28.809 24.313  1   31.11  ? 391 LEU D C   1 
ATOM   8707 O  O   . LEU D 2 221 ? -54.587 -29.181 25.428  1   28.62  ? 391 LEU D O   1 
ATOM   8708 C  CB  . LEU D 2 221 ? -55.773 -27.197 23.074  1   38.26  ? 391 LEU D CB  1 
ATOM   8709 C  CG  . LEU D 2 221 ? -56.222 -25.767 22.737  1   45.92  ? 391 LEU D CG  1 
ATOM   8710 C  CD1 . LEU D 2 221 ? -57.432 -25.699 21.819  1   46.64  ? 391 LEU D CD1 1 
ATOM   8711 C  CD2 . LEU D 2 221 ? -56.551 -25.068 24.05   1   49.37  ? 391 LEU D CD2 1 
ATOM   8712 N  N   . LEU D 2 222 ? -53.597 -29.605 23.437  1   31.21  ? 392 LEU D N   1 
ATOM   8713 C  CA  . LEU D 2 222 ? -53.367 -31.02  23.689  1   30.79  ? 392 LEU D CA  1 
ATOM   8714 C  C   . LEU D 2 222 ? -52.304 -31.199 24.771  1   30.87  ? 392 LEU D C   1 
ATOM   8715 O  O   . LEU D 2 222 ? -52.404 -32.102 25.595  1   31.88  ? 392 LEU D O   1 
ATOM   8716 C  CB  . LEU D 2 222 ? -52.984 -31.766 22.409  1   31.25  ? 392 LEU D CB  1 
ATOM   8717 C  CG  . LEU D 2 222 ? -54.118 -32.193 21.464  1   31.07  ? 392 LEU D CG  1 
ATOM   8718 C  CD1 . LEU D 2 222 ? -53.595 -33.226 20.474  1   27.94  ? 392 LEU D CD1 1 
ATOM   8719 C  CD2 . LEU D 2 222 ? -55.368 -32.709 22.182  1   29.45  ? 392 LEU D CD2 1 
ATOM   8720 N  N   . ASP D 2 223 ? -51.26  -30.368 24.731  1   29.53  ? 393 ASP D N   1 
ATOM   8721 C  CA  . ASP D 2 223 ? -50.217 -30.434 25.741  1   28.96  ? 393 ASP D CA  1 
ATOM   8722 C  C   . ASP D 2 223 ? -50.782 -29.995 27.087  1   26.93  ? 393 ASP D C   1 
ATOM   8723 O  O   . ASP D 2 223 ? -50.475 -30.626 28.092  1   26.35  ? 393 ASP D O   1 
ATOM   8724 C  CB  . ASP D 2 223 ? -48.993 -29.61  25.369  1   30.69  ? 393 ASP D CB  1 
ATOM   8725 C  CG  . ASP D 2 223 ? -48.134 -30.166 24.246  1   32.25  ? 393 ASP D CG  1 
ATOM   8726 O  OD1 . ASP D 2 223 ? -47.717 -31.341 24.367  1   36.47  ? 393 ASP D OD1 1 
ATOM   8727 O  OD2 . ASP D 2 223 ? -47.873 -29.419 23.275  1   30.96  ? 393 ASP D OD2 1 
ATOM   8728 N  N   . LEU D 2 224 ? -51.596 -28.925 27.084  1   24     ? 394 LEU D N   1 
ATOM   8729 C  CA  . LEU D 2 224 ? -52.045 -28.268 28.3    1   23.22  ? 394 LEU D CA  1 
ATOM   8730 C  C   . LEU D 2 224 ? -53.107 -29.111 28.985  1   24.32  ? 394 LEU D C   1 
ATOM   8731 O  O   . LEU D 2 224 ? -53.159 -29.177 30.209  1   26.68  ? 394 LEU D O   1 
ATOM   8732 C  CB  . LEU D 2 224 ? -52.571 -26.869 27.986  1   23.82  ? 394 LEU D CB  1 
ATOM   8733 C  CG  . LEU D 2 224 ? -52.887 -25.967 29.186  1   22.12  ? 394 LEU D CG  1 
ATOM   8734 C  CD1 . LEU D 2 224 ? -51.669 -25.667 30.036  1   22.05  ? 394 LEU D CD1 1 
ATOM   8735 C  CD2 . LEU D 2 224 ? -53.541 -24.666 28.745  1   20.87  ? 394 LEU D CD2 1 
ATOM   8736 N  N   . HIS D 2 225 ? -53.974 -29.728 28.182  1   25.34  ? 395 HIS D N   1 
ATOM   8737 C  CA  . HIS D 2 225 ? -54.949 -30.671 28.704  1   24.58  ? 395 HIS D CA  1 
ATOM   8738 C  C   . HIS D 2 225 ? -54.216 -31.791 29.439  1   25.88  ? 395 HIS D C   1 
ATOM   8739 O  O   . HIS D 2 225 ? -54.609 -32.187 30.534  1   26.61  ? 395 HIS D O   1 
ATOM   8740 C  CB  . HIS D 2 225 ? -55.814 -31.203 27.559  1   23.94  ? 395 HIS D CB  1 
ATOM   8741 C  CG  . HIS D 2 225 ? -56.907 -32.142 27.962  1   23.85  ? 395 HIS D CG  1 
ATOM   8742 N  ND1 . HIS D 2 225 ? -57.63  -31.984 29.128  1   22.76  ? 395 HIS D ND1 1 
ATOM   8743 C  CD2 . HIS D 2 225 ? -57.412 -33.229 27.348  1   21.81  ? 395 HIS D CD2 1 
ATOM   8744 C  CE1 . HIS D 2 225 ? -58.543 -32.933 29.199  1   21.3   ? 395 HIS D CE1 1 
ATOM   8745 N  NE2 . HIS D 2 225 ? -58.428 -33.693 28.131  1   21.13  ? 395 HIS D NE2 1 
ATOM   8746 N  N   . GLN D 2 226 ? -53.136 -32.279 28.816  1   28.18  ? 396 GLN D N   1 
ATOM   8747 C  CA  . GLN D 2 226 ? -52.325 -33.37  29.33   1   31.8   ? 396 GLN D CA  1 
ATOM   8748 C  C   . GLN D 2 226 ? -51.671 -32.933 30.64   1   30.09  ? 396 GLN D C   1 
ATOM   8749 O  O   . GLN D 2 226 ? -51.645 -33.691 31.605  1   29.7   ? 396 GLN D O   1 
ATOM   8750 C  CB  . GLN D 2 226 ? -51.286 -33.751 28.275  1   37.5   ? 396 GLN D CB  1 
ATOM   8751 C  CG  . GLN D 2 226 ? -50.715 -35.161 28.408  1   46.78  ? 396 GLN D CG  1 
ATOM   8752 C  CD  . GLN D 2 226 ? -49.749 -35.543 27.304  1   50.87  ? 396 GLN D CD  1 
ATOM   8753 O  OE1 . GLN D 2 226 ? -49.929 -36.558 26.616  1   52.53  ? 396 GLN D OE1 1 
ATOM   8754 N  NE2 . GLN D 2 226 ? -48.687 -34.76  27.163  1   46.43  ? 396 GLN D NE2 1 
ATOM   8755 N  N   . THR D 2 227 ? -51.168 -31.695 30.67   1   28.19  ? 397 THR D N   1 
ATOM   8756 C  CA  . THR D 2 227 ? -50.539 -31.174 31.87   1   28.97  ? 397 THR D CA  1 
ATOM   8757 C  C   . THR D 2 227 ? -51.563 -31.14  33.011  1   27.99  ? 397 THR D C   1 
ATOM   8758 O  O   . THR D 2 227 ? -51.223 -31.455 34.155  1   26.1   ? 397 THR D O   1 
ATOM   8759 C  CB  . THR D 2 227 ? -49.884 -29.814 31.605  1   28.27  ? 397 THR D CB  1 
ATOM   8760 O  OG1 . THR D 2 227 ? -48.786 -29.99  30.714  1   28.73  ? 397 THR D OG1 1 
ATOM   8761 C  CG2 . THR D 2 227 ? -49.343 -29.176 32.871  1   27.58  ? 397 THR D CG2 1 
ATOM   8762 N  N   . TYR D 2 228 ? -52.817 -30.789 32.677  1   25.6   ? 398 TYR D N   1 
ATOM   8763 C  CA  . TYR D 2 228 ? -53.871 -30.606 33.667  1   25.96  ? 398 TYR D CA  1 
ATOM   8764 C  C   . TYR D 2 228 ? -54.216 -31.952 34.319  1   28.7   ? 398 TYR D C   1 
ATOM   8765 O  O   . TYR D 2 228 ? -54.38  -32.04  35.544  1   28.32  ? 398 TYR D O   1 
ATOM   8766 C  CB  . TYR D 2 228 ? -55.024 -29.855 32.985  1   25.73  ? 398 TYR D CB  1 
ATOM   8767 C  CG  . TYR D 2 228 ? -56.187 -29.414 33.87   1   27.53  ? 398 TYR D CG  1 
ATOM   8768 C  CD1 . TYR D 2 228 ? -56.097 -29.434 35.266  1   27.29  ? 398 TYR D CD1 1 
ATOM   8769 C  CD2 . TYR D 2 228 ? -57.381 -28.951 33.307  1   27.79  ? 398 TYR D CD2 1 
ATOM   8770 C  CE1 . TYR D 2 228 ? -57.162 -29.029 36.063  1   27.74  ? 398 TYR D CE1 1 
ATOM   8771 C  CE2 . TYR D 2 228 ? -58.454 -28.544 34.098  1   27.02  ? 398 TYR D CE2 1 
ATOM   8772 C  CZ  . TYR D 2 228 ? -58.338 -28.576 35.482  1   27.47  ? 398 TYR D CZ  1 
ATOM   8773 O  OH  . TYR D 2 228 ? -59.36  -28.167 36.297  1   26.19  ? 398 TYR D OH  1 
ATOM   8774 N  N   . LEU D 2 229 ? -54.278 -33.007 33.488  1   28.87  ? 399 LEU D N   1 
ATOM   8775 C  CA  . LEU D 2 229 ? -54.676 -34.344 33.898  1   29.55  ? 399 LEU D CA  1 
ATOM   8776 C  C   . LEU D 2 229 ? -53.616 -34.998 34.782  1   30.46  ? 399 LEU D C   1 
ATOM   8777 O  O   . LEU D 2 229 ? -53.944 -35.764 35.679  1   29.49  ? 399 LEU D O   1 
ATOM   8778 C  CB  . LEU D 2 229 ? -54.931 -35.19  32.651  1   29.32  ? 399 LEU D CB  1 
ATOM   8779 C  CG  . LEU D 2 229 ? -56.175 -34.854 31.827  1   26.25  ? 399 LEU D CG  1 
ATOM   8780 C  CD1 . LEU D 2 229 ? -56.073 -35.529 30.478  1   24.92  ? 399 LEU D CD1 1 
ATOM   8781 C  CD2 . LEU D 2 229 ? -57.423 -35.303 32.54   1   24.59  ? 399 LEU D CD2 1 
ATOM   8782 N  N   . ARG D 2 230 ? -52.341 -34.722 34.505  1   34.77  ? 400 ARG D N   1 
ATOM   8783 C  CA  . ARG D 2 230 ? -51.254 -35.346 35.244  1   37.66  ? 400 ARG D CA  1 
ATOM   8784 C  C   . ARG D 2 230 ? -50.855 -34.495 36.445  1   35.86  ? 400 ARG D C   1 
ATOM   8785 O  O   . ARG D 2 230 ? -50.026 -34.924 37.242  1   35.84  ? 400 ARG D O   1 
ATOM   8786 C  CB  . ARG D 2 230 ? -50.013 -35.522 34.36   1   43.49  ? 400 ARG D CB  1 
ATOM   8787 C  CG  . ARG D 2 230 ? -50.276 -36.35  33.11   1   53.51  ? 400 ARG D CG  1 
ATOM   8788 C  CD  . ARG D 2 230 ? -49.084 -36.387 32.168  1   61.33  ? 400 ARG D CD  1 
ATOM   8789 N  NE  . ARG D 2 230 ? -49.418 -37.012 30.881  1   65.87  ? 400 ARG D NE  1 
ATOM   8790 C  CZ  . ARG D 2 230 ? -49.89  -38.236 30.64   1   65.82  ? 400 ARG D CZ  1 
ATOM   8791 N  NH1 . ARG D 2 230 ? -50.049 -39.107 31.618  1   66.22  ? 400 ARG D NH1 1 
ATOM   8792 N  NH2 . ARG D 2 230 ? -50.202 -38.588 29.408  1   62.21  ? 400 ARG D NH2 1 
ATOM   8793 N  N   . ALA D 2 231 ? -51.444 -33.297 36.571  1   32.92  ? 401 ALA D N   1 
ATOM   8794 C  CA  . ALA D 2 231 ? -50.914 -32.294 37.481  1   30.73  ? 401 ALA D CA  1 
ATOM   8795 C  C   . ALA D 2 231 ? -50.799 -32.844 38.903  1   29.14  ? 401 ALA D C   1 
ATOM   8796 O  O   . ALA D 2 231 ? -49.768 -32.684 39.542  1   27.8   ? 401 ALA D O   1 
ATOM   8797 C  CB  . ALA D 2 231 ? -51.734 -31.034 37.407  1   30.99  ? 401 ALA D CB  1 
ATOM   8798 N  N   . PRO D 2 232 ? -51.836 -33.514 39.454  1   28.39  ? 402 PRO D N   1 
ATOM   8799 C  CA  . PRO D 2 232 ? -51.715 -34.153 40.767  1   27.92  ? 402 PRO D CA  1 
ATOM   8800 C  C   . PRO D 2 232 ? -50.507 -35.059 41.004  1   27.75  ? 402 PRO D C   1 
ATOM   8801 O  O   . PRO D 2 232 ? -50.168 -35.336 42.15   1   27.09  ? 402 PRO D O   1 
ATOM   8802 C  CB  . PRO D 2 232 ? -53.031 -34.922 40.874  1   26.86  ? 402 PRO D CB  1 
ATOM   8803 C  CG  . PRO D 2 232 ? -54.008 -34.093 40.076  1   26.6   ? 402 PRO D CG  1 
ATOM   8804 C  CD  . PRO D 2 232 ? -53.19  -33.618 38.889  1   27.21  ? 402 PRO D CD  1 
ATOM   8805 N  N   . GLN D 2 233 ? -49.85  -35.507 39.927  1   28.27  ? 403 GLN D N   1 
ATOM   8806 C  CA  . GLN D 2 233 ? -48.727 -36.433 40.023  1   29.09  ? 403 GLN D CA  1 
ATOM   8807 C  C   . GLN D 2 233 ? -47.38  -35.77  39.719  1   27.9   ? 403 GLN D C   1 
ATOM   8808 O  O   . GLN D 2 233 ? -46.348 -36.409 39.91   1   28.73  ? 403 GLN D O   1 
ATOM   8809 C  CB  . GLN D 2 233 ? -48.865 -37.621 39.063  1   32.36  ? 403 GLN D CB  1 
ATOM   8810 C  CG  . GLN D 2 233 ? -49.578 -38.853 39.612  1   32.18  ? 403 GLN D CG  1 
ATOM   8811 C  CD  . GLN D 2 233 ? -51.084 -38.718 39.626  1   35.21  ? 403 GLN D CD  1 
ATOM   8812 O  OE1 . GLN D 2 233 ? -51.773 -39.177 40.55   1   38.67  ? 403 GLN D OE1 1 
ATOM   8813 N  NE2 . GLN D 2 233 ? -51.612 -38.11  38.572  1   34.23  ? 403 GLN D NE2 1 
ATOM   8814 N  N   . HIS D 2 234 ? -47.379 -34.517 39.23   1   27.31  ? 404 HIS D N   1 
ATOM   8815 C  CA  . HIS D 2 234 ? -46.157 -33.801 38.871  1   23.72  ? 404 HIS D CA  1 
ATOM   8816 C  C   . HIS D 2 234 ? -45.249 -33.721 40.1    1   21.27  ? 404 HIS D C   1 
ATOM   8817 O  O   . HIS D 2 234 ? -45.732 -33.619 41.218  1   19.85  ? 404 HIS D O   1 
ATOM   8818 C  CB  . HIS D 2 234 ? -46.507 -32.447 38.238  1   25.22  ? 404 HIS D CB  1 
ATOM   8819 C  CG  . HIS D 2 234 ? -45.408 -31.788 37.448  1   30.69  ? 404 HIS D CG  1 
ATOM   8820 N  ND1 . HIS D 2 234 ? -44.175 -31.394 37.944  1   31.74  ? 404 HIS D ND1 1 
ATOM   8821 C  CD2 . HIS D 2 234 ? -45.409 -31.419 36.153  1   30.4   ? 404 HIS D CD2 1 
ATOM   8822 C  CE1 . HIS D 2 234 ? -43.458 -30.846 36.973  1   31.34  ? 404 HIS D CE1 1 
ATOM   8823 N  NE2 . HIS D 2 234 ? -44.186 -30.865 35.871  1   31.1   ? 404 HIS D NE2 1 
ATOM   8824 N  N   . ALA D 2 235 ? -43.932 -33.809 39.898  1   21.08  ? 405 ALA D N   1 
ATOM   8825 C  CA  . ALA D 2 235 ? -42.981 -33.674 40.99   1   22.17  ? 405 ALA D CA  1 
ATOM   8826 C  C   . ALA D 2 235 ? -43.16  -32.322 41.673  1   25.72  ? 405 ALA D C   1 
ATOM   8827 O  O   . ALA D 2 235 ? -42.896 -32.211 42.868  1   27.32  ? 405 ALA D O   1 
ATOM   8828 C  CB  . ALA D 2 235 ? -41.553 -33.86  40.504  1   20.93  ? 405 ALA D CB  1 
ATOM   8829 N  N   . GLN D 2 236 ? -43.588 -31.304 40.908  1   27.55  ? 406 GLN D N   1 
ATOM   8830 C  CA  . GLN D 2 236 ? -43.785 -29.952 41.419  1   32.4   ? 406 GLN D CA  1 
ATOM   8831 C  C   . GLN D 2 236 ? -45.266 -29.651 41.663  1   36.81  ? 406 GLN D C   1 
ATOM   8832 O  O   . GLN D 2 236 ? -46.111 -29.806 40.771  1   41.25  ? 406 GLN D O   1 
ATOM   8833 C  CB  . GLN D 2 236 ? -43.171 -28.915 40.48   1   32.78  ? 406 GLN D CB  1 
ATOM   8834 C  CG  . GLN D 2 236 ? -41.678 -28.712 40.677  1   33.06  ? 406 GLN D CG  1 
ATOM   8835 C  CD  . GLN D 2 236 ? -40.846 -29.909 40.28   1   41.31  ? 406 GLN D CD  1 
ATOM   8836 O  OE1 . GLN D 2 236 ? -40.905 -30.389 39.137  1   49.32  ? 406 GLN D OE1 1 
ATOM   8837 N  NE2 . GLN D 2 236 ? -40.047 -30.386 41.228  1   40.56  ? 406 GLN D NE2 1 
ATOM   8838 N  N   . GLN D 2 237 ? -45.548 -29.146 42.874  1   35.55  ? 407 GLN D N   1 
ATOM   8839 C  CA  . GLN D 2 237 ? -46.891 -29.114 43.421  1   31.92  ? 407 GLN D CA  1 
ATOM   8840 C  C   . GLN D 2 237 ? -47.318 -27.724 43.894  1   30.56  ? 407 GLN D C   1 
ATOM   8841 O  O   . GLN D 2 237 ? -48.49  -27.556 44.217  1   31.78  ? 407 GLN D O   1 
ATOM   8842 C  CB  . GLN D 2 237 ? -46.947 -30.086 44.599  1   32.44  ? 407 GLN D CB  1 
ATOM   8843 C  CG  . GLN D 2 237 ? -47.104 -31.547 44.196  1   33.39  ? 407 GLN D CG  1 
ATOM   8844 C  CD  . GLN D 2 237 ? -48.268 -31.78  43.255  1   35.08  ? 407 GLN D CD  1 
ATOM   8845 O  OE1 . GLN D 2 237 ? -49.411 -31.362 43.498  1   33.31  ? 407 GLN D OE1 1 
ATOM   8846 N  NE2 . GLN D 2 237 ? -47.978 -32.459 42.155  1   36.05  ? 407 GLN D NE2 1 
ATOM   8847 N  N   . SER D 2 238 ? -46.396 -26.75  43.95   1   27.27  ? 408 SER D N   1 
ATOM   8848 C  CA  . SER D 2 238 ? -46.641 -25.497 44.654  1   27.41  ? 408 SER D CA  1 
ATOM   8849 C  C   . SER D 2 238 ? -47.82  -24.722 44.058  1   30.01  ? 408 SER D C   1 
ATOM   8850 O  O   . SER D 2 238 ? -48.502 -23.988 44.786  1   30.84  ? 408 SER D O   1 
ATOM   8851 C  CB  . SER D 2 238 ? -45.426 -24.61  44.673  1   26.36  ? 408 SER D CB  1 
ATOM   8852 O  OG  . SER D 2 238 ? -44.29  -25.257 45.211  1   27.16  ? 408 SER D OG  1 
ATOM   8853 N  N   . ILE D 2 239 ? -48.022 -24.859 42.737  1   27.53  ? 409 ILE D N   1 
ATOM   8854 C  CA  . ILE D 2 239 ? -49.052 -24.113 42.038  1   27.01  ? 409 ILE D CA  1 
ATOM   8855 C  C   . ILE D 2 239 ? -50.41  -24.707 42.389  1   28.77  ? 409 ILE D C   1 
ATOM   8856 O  O   . ILE D 2 239 ? -51.369 -23.969 42.617  1   30.89  ? 409 ILE D O   1 
ATOM   8857 C  CB  . ILE D 2 239 ? -48.794 -24.095 40.522  1   26.97  ? 409 ILE D CB  1 
ATOM   8858 C  CG1 . ILE D 2 239 ? -47.497 -23.373 40.182  1   27.83  ? 409 ILE D CG1 1 
ATOM   8859 C  CG2 . ILE D 2 239 ? -49.97  -23.478 39.771  1   25.73  ? 409 ILE D CG2 1 
ATOM   8860 C  CD1 . ILE D 2 239 ? -47.015 -23.55  38.75   1   27.97  ? 409 ILE D CD1 1 
ATOM   8861 N  N   . ARG D 2 240 ? -50.474 -26.041 42.445  1   29.6   ? 410 ARG D N   1 
ATOM   8862 C  CA  . ARG D 2 240 ? -51.682 -26.731 42.877  1   30.05  ? 410 ARG D CA  1 
ATOM   8863 C  C   . ARG D 2 240 ? -52.064 -26.274 44.285  1   30.73  ? 410 ARG D C   1 
ATOM   8864 O  O   . ARG D 2 240 ? -53.218 -25.914 44.505  1   31.43  ? 410 ARG D O   1 
ATOM   8865 C  CB  . ARG D 2 240 ? -51.554 -28.258 42.797  1   29.8   ? 410 ARG D CB  1 
ATOM   8866 C  CG  . ARG D 2 240 ? -51.771 -28.854 41.411  1   30.99  ? 410 ARG D CG  1 
ATOM   8867 C  CD  . ARG D 2 240 ? -51.95  -30.384 41.369  1   30.78  ? 410 ARG D CD  1 
ATOM   8868 N  NE  . ARG D 2 240 ? -53.244 -30.885 41.858  1   28.42  ? 410 ARG D NE  1 
ATOM   8869 C  CZ  . ARG D 2 240 ? -53.408 -31.607 42.964  1   26.79  ? 410 ARG D CZ  1 
ATOM   8870 N  NH1 . ARG D 2 240 ? -54.618 -31.903 43.387  1   26.34  ? 410 ARG D NH1 1 
ATOM   8871 N  NH2 . ARG D 2 240 ? -52.372 -32.002 43.678  1   25.97  ? 410 ARG D NH2 1 
ATOM   8872 N  N   . GLU D 2 241 ? -51.106 -26.324 45.229  1   30.45  ? 411 GLU D N   1 
ATOM   8873 C  CA  . GLU D 2 241 ? -51.318 -25.894 46.607  1   33.5   ? 411 GLU D CA  1 
ATOM   8874 C  C   . GLU D 2 241 ? -51.802 -24.447 46.642  1   33.23  ? 411 GLU D C   1 
ATOM   8875 O  O   . GLU D 2 241 ? -52.752 -24.122 47.361  1   33.86  ? 411 GLU D O   1 
ATOM   8876 C  CB  . GLU D 2 241 ? -50.055 -25.981 47.468  1   34.77  ? 411 GLU D CB  1 
ATOM   8877 C  CG  . GLU D 2 241 ? -49.505 -27.4   47.597  1   40.71  ? 411 GLU D CG  1 
ATOM   8878 C  CD  . GLU D 2 241 ? -50.49  -28.474 48.068  1   46.13  ? 411 GLU D CD  1 
ATOM   8879 O  OE1 . GLU D 2 241 ? -51.584 -28.131 48.579  1   46.22  ? 411 GLU D OE1 1 
ATOM   8880 O  OE2 . GLU D 2 241 ? -50.176 -29.682 47.905  1   47.35  ? 411 GLU D OE2 1 
ATOM   8881 N  N   . LYS D 2 242 ? -51.142 -23.601 45.847  1   28.25  ? 412 LYS D N   1 
ATOM   8882 C  CA  . LYS D 2 242 ? -51.458 -22.191 45.816  1   26.67  ? 412 LYS D CA  1 
ATOM   8883 C  C   . LYS D 2 242 ? -52.937 -22.027 45.479  1   29.34  ? 412 LYS D C   1 
ATOM   8884 O  O   . LYS D 2 242 ? -53.648 -21.329 46.207  1   32.59  ? 412 LYS D O   1 
ATOM   8885 C  CB  . LYS D 2 242 ? -50.5   -21.519 44.825  1   26.53  ? 412 LYS D CB  1 
ATOM   8886 C  CG  . LYS D 2 242 ? -50.832 -20.101 44.367  1   23.42  ? 412 LYS D CG  1 
ATOM   8887 C  CD  . LYS D 2 242 ? -49.732 -19.546 43.48   1   22.67  ? 412 LYS D CD  1 
ATOM   8888 C  CE  . LYS D 2 242 ? -50.013 -18.256 42.787  1   22.69  ? 412 LYS D CE  1 
ATOM   8889 N  NZ  . LYS D 2 242 ? -48.829 -17.761 42.063  1   23.62  ? 412 LYS D NZ  1 
ATOM   8890 N  N   . TYR D 2 243 ? -53.39  -22.722 44.414  1   27.63  ? 413 TYR D N   1 
ATOM   8891 C  CA  . TYR D 2 243 ? -54.7   -22.519 43.808  1   25.63  ? 413 TYR D CA  1 
ATOM   8892 C  C   . TYR D 2 243 ? -55.777 -23.394 44.46   1   27.35  ? 413 TYR D C   1 
ATOM   8893 O  O   . TYR D 2 243 ? -56.878 -23.525 43.923  1   25.62  ? 413 TYR D O   1 
ATOM   8894 C  CB  . TYR D 2 243 ? -54.595 -22.722 42.291  1   24.8   ? 413 TYR D CB  1 
ATOM   8895 C  CG  . TYR D 2 243 ? -54.038 -21.538 41.515  1   23.88  ? 413 TYR D CG  1 
ATOM   8896 C  CD1 . TYR D 2 243 ? -52.666 -21.34  41.387  1   24.59  ? 413 TYR D CD1 1 
ATOM   8897 C  CD2 . TYR D 2 243 ? -54.883 -20.61  40.915  1   23.47  ? 413 TYR D CD2 1 
ATOM   8898 C  CE1 . TYR D 2 243 ? -52.147 -20.257 40.689  1   23.81  ? 413 TYR D CE1 1 
ATOM   8899 C  CE2 . TYR D 2 243 ? -54.382 -19.526 40.213  1   22.83  ? 413 TYR D CE2 1 
ATOM   8900 C  CZ  . TYR D 2 243 ? -53.014 -19.354 40.101  1   24.14  ? 413 TYR D CZ  1 
ATOM   8901 O  OH  . TYR D 2 243 ? -52.53  -18.283 39.426  1   27.46  ? 413 TYR D OH  1 
ATOM   8902 N  N   . LYS D 2 244 ? -55.463 -23.989 45.618  1   28.76  ? 414 LYS D N   1 
ATOM   8903 C  CA  . LYS D 2 244 ? -56.466 -24.604 46.471  1   31.53  ? 414 LYS D CA  1 
ATOM   8904 C  C   . LYS D 2 244 ? -57.139 -23.537 47.331  1   34.12  ? 414 LYS D C   1 
ATOM   8905 O  O   . LYS D 2 244 ? -58.302 -23.681 47.703  1   35.43  ? 414 LYS D O   1 
ATOM   8906 C  CB  . LYS D 2 244 ? -55.822 -25.613 47.423  1   32.79  ? 414 LYS D CB  1 
ATOM   8907 C  CG  . LYS D 2 244 ? -55.299 -26.853 46.738  1   33.53  ? 414 LYS D CG  1 
ATOM   8908 C  CD  . LYS D 2 244 ? -54.705 -27.877 47.698  1   36.39  ? 414 LYS D CD  1 
ATOM   8909 C  CE  . LYS D 2 244 ? -54.473 -29.214 47.029  1   36.87  ? 414 LYS D CE  1 
ATOM   8910 N  NZ  . LYS D 2 244 ? -53.833 -30.154 47.948  1   33.88  ? 414 LYS D NZ  1 
ATOM   8911 N  N   . ASN D 2 245 ? -56.387 -22.483 47.664  1   37.53  ? 415 ASN D N   1 
ATOM   8912 C  CA  . ASN D 2 245 ? -56.863 -21.432 48.549  1   44.17  ? 415 ASN D CA  1 
ATOM   8913 C  C   . ASN D 2 245 ? -58.074 -20.741 47.916  1   43.08  ? 415 ASN D C   1 
ATOM   8914 O  O   . ASN D 2 245 ? -58.183 -20.633 46.689  1   41.26  ? 415 ASN D O   1 
ATOM   8915 C  CB  . ASN D 2 245 ? -55.732 -20.493 48.977  1   53.12  ? 415 ASN D CB  1 
ATOM   8916 C  CG  . ASN D 2 245 ? -56.17  -19.422 49.96   1   65.86  ? 415 ASN D CG  1 
ATOM   8917 O  OD1 . ASN D 2 245 ? -56.073 -18.223 49.654  1   67.85  ? 415 ASN D OD1 1 
ATOM   8918 N  ND2 . ASN D 2 245 ? -56.643 -19.818 51.14   1   65.84  ? 415 ASN D ND2 1 
ATOM   8919 N  N   . SER D 2 246 ? -58.966 -20.264 48.798  1   41.18  ? 416 SER D N   1 
ATOM   8920 C  CA  . SER D 2 246 ? -60.187 -19.582 48.415  1   40.22  ? 416 SER D CA  1 
ATOM   8921 C  C   . SER D 2 246 ? -59.872 -18.307 47.643  1   39.29  ? 416 SER D C   1 
ATOM   8922 O  O   . SER D 2 246 ? -60.748 -17.807 46.954  1   39.24  ? 416 SER D O   1 
ATOM   8923 C  CB  . SER D 2 246 ? -61.073 -19.279 49.6    1   40.26  ? 416 SER D CB  1 
ATOM   8924 O  OG  . SER D 2 246 ? -60.765 -18.007 50.149  1   42.92  ? 416 SER D OG  1 
ATOM   8925 N  N   . LYS D 2 247 ? -58.652 -17.769 47.794  1   39.29  ? 417 LYS D N   1 
ATOM   8926 C  CA  . LYS D 2 247 ? -58.24  -16.618 47.004  1   40.73  ? 417 LYS D CA  1 
ATOM   8927 C  C   . LYS D 2 247 ? -58.471 -16.922 45.526  1   39.87  ? 417 LYS D C   1 
ATOM   8928 O  O   . LYS D 2 247 ? -59.003 -16.077 44.809  1   38.53  ? 417 LYS D O   1 
ATOM   8929 C  CB  . LYS D 2 247 ? -56.813 -16.175 47.346  1   42.14  ? 417 LYS D CB  1 
ATOM   8930 C  CG  . LYS D 2 247 ? -56.096 -15.292 46.335  1   45.05  ? 417 LYS D CG  1 
ATOM   8931 C  CD  . LYS D 2 247 ? -54.807 -14.652 46.854  1   51.01  ? 417 LYS D CD  1 
ATOM   8932 C  CE  . LYS D 2 247 ? -54.09  -15.459 47.922  1   54.51  ? 417 LYS D CE  1 
ATOM   8933 N  NZ  . LYS D 2 247 ? -52.859 -14.831 48.43   1   48.81  ? 417 LYS D NZ  1 
ATOM   8934 N  N   . TYR D 2 248 ? -58.099 -18.144 45.102  1   39.81  ? 418 TYR D N   1 
ATOM   8935 C  CA  . TYR D 2 248 ? -58.227 -18.564 43.713  1   38.36  ? 418 TYR D CA  1 
ATOM   8936 C  C   . TYR D 2 248 ? -59.43  -19.49  43.529  1   39.58  ? 418 TYR D C   1 
ATOM   8937 O  O   . TYR D 2 248 ? -59.453 -20.264 42.576  1   40.72  ? 418 TYR D O   1 
ATOM   8938 C  CB  . TYR D 2 248 ? -56.93  -19.203 43.214  1   35.65  ? 418 TYR D CB  1 
ATOM   8939 C  CG  . TYR D 2 248 ? -55.701 -18.327 43.407  1   34.56  ? 418 TYR D CG  1 
ATOM   8940 C  CD1 . TYR D 2 248 ? -55.458 -17.234 42.573  1   33.14  ? 418 TYR D CD1 1 
ATOM   8941 C  CD2 . TYR D 2 248 ? -54.794 -18.598 44.43   1   31.56  ? 418 TYR D CD2 1 
ATOM   8942 C  CE1 . TYR D 2 248 ? -54.336 -16.438 42.754  1   33.96  ? 418 TYR D CE1 1 
ATOM   8943 C  CE2 . TYR D 2 248 ? -53.695 -17.787 44.64   1   33.43  ? 418 TYR D CE2 1 
ATOM   8944 C  CZ  . TYR D 2 248 ? -53.459 -16.708 43.799  1   36.7   ? 418 TYR D CZ  1 
ATOM   8945 O  OH  . TYR D 2 248 ? -52.345 -15.931 44.025  1   37.79  ? 418 TYR D OH  1 
ATOM   8946 N  N   . HIS D 2 249 ? -60.427 -19.381 44.425  1   39.12  ? 419 HIS D N   1 
ATOM   8947 C  CA  . HIS D 2 249 ? -61.695 -20.105 44.366  1   38.68  ? 419 HIS D CA  1 
ATOM   8948 C  C   . HIS D 2 249 ? -61.486 -21.622 44.36   1   34.52  ? 419 HIS D C   1 
ATOM   8949 O  O   . HIS D 2 249 ? -62.331 -22.344 43.84   1   36.06  ? 419 HIS D O   1 
ATOM   8950 C  CB  . HIS D 2 249 ? -62.559 -19.652 43.174  1   43.6   ? 419 HIS D CB  1 
ATOM   8951 C  CG  . HIS D 2 249 ? -62.779 -18.172 43.091  1   52.23  ? 419 HIS D CG  1 
ATOM   8952 N  ND1 . HIS D 2 249 ? -61.773 -17.286 42.754  1   58.1   ? 419 HIS D ND1 1 
ATOM   8953 C  CD2 . HIS D 2 249 ? -63.855 -17.417 43.344  1   52.52  ? 419 HIS D CD2 1 
ATOM   8954 C  CE1 . HIS D 2 249 ? -62.242 -16.04  42.785  1   54.78  ? 419 HIS D CE1 1 
ATOM   8955 N  NE2 . HIS D 2 249 ? -63.504 -16.096 43.138  1   51.9   ? 419 HIS D NE2 1 
ATOM   8956 N  N   . GLY D 2 250 ? -60.368 -22.099 44.924  1   30.46  ? 420 GLY D N   1 
ATOM   8957 C  CA  . GLY D 2 250 ? -60.032 -23.515 44.971  1   30.07  ? 420 GLY D CA  1 
ATOM   8958 C  C   . GLY D 2 250 ? -60.059 -24.228 43.615  1   31.14  ? 420 GLY D C   1 
ATOM   8959 O  O   . GLY D 2 250 ? -60.384 -25.411 43.566  1   31.24  ? 420 GLY D O   1 
ATOM   8960 N  N   . VAL D 2 251 ? -59.671 -23.538 42.531  1   30.82  ? 421 VAL D N   1 
ATOM   8961 C  CA  . VAL D 2 251 ? -59.859 -24.057 41.18   1   30.7   ? 421 VAL D CA  1 
ATOM   8962 C  C   . VAL D 2 251 ? -59.025 -25.321 40.948  1   32.88  ? 421 VAL D C   1 
ATOM   8963 O  O   . VAL D 2 251 ? -59.406 -26.175 40.145  1   34.91  ? 421 VAL D O   1 
ATOM   8964 C  CB  . VAL D 2 251 ? -59.659 -23.043 40.037  1   30.61  ? 421 VAL D CB  1 
ATOM   8965 C  CG1 . VAL D 2 251 ? -60.785 -22.019 39.966  1   29.66  ? 421 VAL D CG1 1 
ATOM   8966 C  CG2 . VAL D 2 251 ? -58.3   -22.357 40.085  1   30.17  ? 421 VAL D CG2 1 
ATOM   8967 N  N   . SER D 2 252 ? -57.889 -25.44  41.648  1   34.55  ? 422 SER D N   1 
ATOM   8968 C  CA  . SER D 2 252 ? -56.983 -26.568 41.454  1   33.42  ? 422 SER D CA  1 
ATOM   8969 C  C   . SER D 2 252 ? -57.619 -27.883 41.911  1   31.41  ? 422 SER D C   1 
ATOM   8970 O  O   . SER D 2 252 ? -57.08  -28.94  41.618  1   30.3   ? 422 SER D O   1 
ATOM   8971 C  CB  . SER D 2 252 ? -55.639 -26.349 42.13   1   33.58  ? 422 SER D CB  1 
ATOM   8972 O  OG  . SER D 2 252 ? -55.662 -26.787 43.48   1   34.67  ? 422 SER D OG  1 
ATOM   8973 N  N   . LEU D 2 253 ? -58.742 -27.798 42.639  1   30.19  ? 423 LEU D N   1 
ATOM   8974 C  CA  . LEU D 2 253 ? -59.449 -28.949 43.185  1   31.23  ? 423 LEU D CA  1 
ATOM   8975 C  C   . LEU D 2 253 ? -60.631 -29.346 42.297  1   30.84  ? 423 LEU D C   1 
ATOM   8976 O  O   . LEU D 2 253 ? -61.381 -30.251 42.642  1   29.02  ? 423 LEU D O   1 
ATOM   8977 C  CB  . LEU D 2 253 ? -59.895 -28.663 44.623  1   29.52  ? 423 LEU D CB  1 
ATOM   8978 C  CG  . LEU D 2 253 ? -58.798 -28.691 45.697  1   30.56  ? 423 LEU D CG  1 
ATOM   8979 C  CD1 . LEU D 2 253 ? -59.288 -28.105 47.011  1   29.18  ? 423 LEU D CD1 1 
ATOM   8980 C  CD2 . LEU D 2 253 ? -58.257 -30.096 45.938  1   29.9   ? 423 LEU D CD2 1 
ATOM   8981 N  N   . LEU D 2 254 ? -60.81  -28.655 41.165  1   33.52  ? 424 LEU D N   1 
ATOM   8982 C  CA  . LEU D 2 254 ? -61.794 -29.05  40.168  1   34.28  ? 424 LEU D CA  1 
ATOM   8983 C  C   . LEU D 2 254 ? -61.218 -30.178 39.315  1   37.43  ? 424 LEU D C   1 
ATOM   8984 O  O   . LEU D 2 254 ? -60.059 -30.111 38.914  1   41.19  ? 424 LEU D O   1 
ATOM   8985 C  CB  . LEU D 2 254 ? -62.18  -27.856 39.294  1   33.25  ? 424 LEU D CB  1 
ATOM   8986 C  CG  . LEU D 2 254 ? -63.015 -26.74  39.931  1   33.95  ? 424 LEU D CG  1 
ATOM   8987 C  CD1 . LEU D 2 254 ? -63.308 -25.66  38.889  1   31.81  ? 424 LEU D CD1 1 
ATOM   8988 C  CD2 . LEU D 2 254 ? -64.304 -27.279 40.556  1   34.73  ? 424 LEU D CD2 1 
ATOM   8989 N  N   . ASN D 2 255 ? -62.046 -31.195 39.029  1   40.54  ? 425 ASN D N   1 
ATOM   8990 C  CA  . ASN D 2 255 ? -61.653 -32.299 38.169  1   40.37  ? 425 ASN D CA  1 
ATOM   8991 C  C   . ASN D 2 255 ? -61.548 -31.821 36.726  1   37.74  ? 425 ASN D C   1 
ATOM   8992 O  O   . ASN D 2 255 ? -62.503 -31.259 36.188  1   38.33  ? 425 ASN D O   1 
ATOM   8993 C  CB  . ASN D 2 255 ? -62.623 -33.471 38.254  1   42.15  ? 425 ASN D CB  1 
ATOM   8994 C  CG  . ASN D 2 255 ? -62.445 -34.268 39.522  1   46.59  ? 425 ASN D CG  1 
ATOM   8995 O  OD1 . ASN D 2 255 ? -63.437 -34.657 40.146  1   47.38  ? 425 ASN D OD1 1 
ATOM   8996 N  ND2 . ASN D 2 255 ? -61.203 -34.544 39.898  1   48.64  ? 425 ASN D ND2 1 
ATOM   8997 N  N   . PRO D 2 256 ? -60.404 -32.081 36.051  1   33.19  ? 426 PRO D N   1 
ATOM   8998 C  CA  . PRO D 2 256 ? -60.28  -31.78  34.624  1   30.82  ? 426 PRO D CA  1 
ATOM   8999 C  C   . PRO D 2 256 ? -61.251 -32.608 33.79   1   30.17  ? 426 PRO D C   1 
ATOM   9000 O  O   . PRO D 2 256 ? -61.53  -33.753 34.14   1   28.78  ? 426 PRO D O   1 
ATOM   9001 C  CB  . PRO D 2 256 ? -58.818 -32.134 34.302  1   31.04  ? 426 PRO D CB  1 
ATOM   9002 C  CG  . PRO D 2 256 ? -58.374 -33.088 35.407  1   30.7   ? 426 PRO D CG  1 
ATOM   9003 C  CD  . PRO D 2 256 ? -59.191 -32.694 36.623  1   31.66  ? 426 PRO D CD  1 
ATOM   9004 N  N   . PRO D 2 257 ? -61.769 -32.081 32.653  1   31.25  ? 427 PRO D N   1 
ATOM   9005 C  CA  . PRO D 2 257 ? -62.592 -32.885 31.743  1   31.52  ? 427 PRO D CA  1 
ATOM   9006 C  C   . PRO D 2 257 ? -61.718 -34.011 31.198  1   33.65  ? 427 PRO D C   1 
ATOM   9007 O  O   . PRO D 2 257 ? -60.496 -33.861 31.127  1   33.86  ? 427 PRO D O   1 
ATOM   9008 C  CB  . PRO D 2 257 ? -63.028 -31.903 30.64   1   31.76  ? 427 PRO D CB  1 
ATOM   9009 C  CG  . PRO D 2 257 ? -62.004 -30.773 30.717  1   33.14  ? 427 PRO D CG  1 
ATOM   9010 C  CD  . PRO D 2 257 ? -61.553 -30.704 32.168  1   30.95  ? 427 PRO D CD  1 
ATOM   9011 N  N   . GLU D 2 258 ? -62.341 -35.142 30.846  1   35.73  ? 428 GLU D N   1 
ATOM   9012 C  CA  . GLU D 2 258 ? -61.578 -36.284 30.369  1   36.06  ? 428 GLU D CA  1 
ATOM   9013 C  C   . GLU D 2 258 ? -61.251 -36.134 28.883  1   35.58  ? 428 GLU D C   1 
ATOM   9014 O  O   . GLU D 2 258 ? -60.178 -36.56  28.45   1   30.78  ? 428 GLU D O   1 
ATOM   9015 C  CB  . GLU D 2 258 ? -62.249 -37.595 30.765  1   38.44  ? 428 GLU D CB  1 
ATOM   9016 C  CG  . GLU D 2 258 ? -61.942 -37.964 32.213  1   40.82  ? 428 GLU D CG  1 
ATOM   9017 C  CD  . GLU D 2 258 ? -62.887 -38.915 32.932  1   43.6   ? 428 GLU D CD  1 
ATOM   9018 O  OE1 . GLU D 2 258 ? -63.635 -39.722 32.325  1   41.79  ? 428 GLU D OE1 1 
ATOM   9019 O  OE2 . GLU D 2 258 ? -62.877 -38.794 34.173  1   44.35  ? 428 GLU D OE2 1 
ATOM   9020 N  N   . THR D 2 259 ? -62.183 -35.527 28.125  1   36.95  ? 429 THR D N   1 
ATOM   9021 C  CA  . THR D 2 259 ? -62.038 -35.299 26.689  1   39.71  ? 429 THR D CA  1 
ATOM   9022 C  C   . THR D 2 259 ? -62.39  -33.851 26.359  1   38.73  ? 429 THR D C   1 
ATOM   9023 O  O   . THR D 2 259 ? -63.13  -33.208 27.097  1   37.88  ? 429 THR D O   1 
ATOM   9024 C  CB  . THR D 2 259 ? -62.894 -36.25  25.842  1   43.78  ? 429 THR D CB  1 
ATOM   9025 O  OG1 . THR D 2 259 ? -64.261 -35.865 25.985  1   48.72  ? 429 THR D OG1 1 
ATOM   9026 C  CG2 . THR D 2 259 ? -62.668 -37.726 26.134  1   43.25  ? 429 THR D CG2 1 
ATOM   9027 N  N   . LEU D 2 260 ? -61.898 -33.38  25.206  1   39.2   ? 430 LEU D N   1 
ATOM   9028 C  CA  . LEU D 2 260 ? -62.077 -32.001 24.775  1   41.36  ? 430 LEU D CA  1 
ATOM   9029 C  C   . LEU D 2 260 ? -63.114 -31.89  23.659  1   45.97  ? 430 LEU D C   1 
ATOM   9030 O  O   . LEU D 2 260 ? -63.497 -30.79  23.258  1   47.03  ? 430 LEU D O   1 
ATOM   9031 C  CB  . LEU D 2 260 ? -60.73  -31.438 24.33   1   38.05  ? 430 LEU D CB  1 
ATOM   9032 C  CG  . LEU D 2 260 ? -59.666 -31.393 25.425  1   38.93  ? 430 LEU D CG  1 
ATOM   9033 C  CD1 . LEU D 2 260 ? -58.394 -30.758 24.904  1   41.56  ? 430 LEU D CD1 1 
ATOM   9034 C  CD2 . LEU D 2 260 ? -60.198 -30.673 26.657  1   35.16  ? 430 LEU D CD2 1 
ATOM   9035 N  N   . ASN D 2 261 ? -63.542 -33.039 23.129  1   51.11  ? 431 ASN D N   1 
ATOM   9036 C  CA  . ASN D 2 261 ? -64.497 -33.037 22.039  1   57.31  ? 431 ASN D CA  1 
ATOM   9037 C  C   . ASN D 2 261 ? -63.905 -32.181 20.925  1   55.55  ? 431 ASN D C   1 
ATOM   9038 O  O   . ASN D 2 261 ? -64.517 -31.232 20.459  1   50.83  ? 431 ASN D O   1 
ATOM   9039 C  CB  . ASN D 2 261 ? -65.896 -32.681 22.54   1   65.79  ? 431 ASN D CB  1 
ATOM   9040 C  CG  . ASN D 2 261 ? -66.568 -33.854 23.222  1   76.82  ? 431 ASN D CG  1 
ATOM   9041 O  OD1 . ASN D 2 261 ? -66.026 -34.428 24.176  1   83.75  ? 431 ASN D OD1 1 
ATOM   9042 N  ND2 . ASN D 2 261 ? -67.735 -34.251 22.731  1   79.71  ? 431 ASN D ND2 1 
ATOM   9043 N  N   . VAL D 2 262 ? -62.674 -32.505 20.524  1   58.74  ? 432 VAL D N   1 
ATOM   9044 C  CA  . VAL D 2 262 ? -62.109 -31.94  19.313  1   56.53  ? 432 VAL D CA  1 
ATOM   9045 C  C   . VAL D 2 262 ? -62.678 -32.77  18.155  1   61.81  ? 432 VAL D C   1 
ATOM   9046 O  O   . VAL D 2 262 ? -63.107 -32.16  17.16   1   66.95  ? 432 VAL D O   1 
ATOM   9047 C  CB  . VAL D 2 262 ? -60.57  -31.983 19.333  1   51.69  ? 432 VAL D CB  1 
ATOM   9048 C  CG1 . VAL D 2 262 ? -59.997 -30.849 20.171  1   49.14  ? 432 VAL D CG1 1 
ATOM   9049 C  CG2 . VAL D 2 262 ? -60.059 -33.333 19.825  1   48.15  ? 432 VAL D CG2 1 
HETATM 9050 C  C4  . IJX E 3 .   ? 14.136  -23.617 -6.633  0.5 36.95  ? 301 IJX A C4  1 
HETATM 9051 C  C5  . IJX E 3 .   ? 13.786  -24.209 -7.833  0.5 38     ? 301 IJX A C5  1 
HETATM 9052 C  C6  . IJX E 3 .   ? 14.288  -25.456 -8.13   0.5 39.59  ? 301 IJX A C6  1 
HETATM 9053 C  C7  . IJX E 3 .   ? 15.122  -26.128 -7.254  0.5 35.09  ? 301 IJX A C7  1 
HETATM 9054 C  C8  . IJX E 3 .   ? 15.476  -25.532 -6.051  0.5 32.82  ? 301 IJX A C8  1 
HETATM 9055 N  N1  . IJX E 3 .   ? 15.316  -23.598 -4.542  0.5 33.86  ? 301 IJX A N1  1 
HETATM 9056 C  C3  . IJX E 3 .   ? 15.004  -24.258 -5.749  0.5 33.94  ? 301 IJX A C3  1 
HETATM 9057 C  C1  . IJX E 3 .   ? 13.757  -21.765 -4.91   0.5 33.37  ? 301 IJX A C1  1 
HETATM 9058 C  C2  . IJX E 3 .   ? 14.784  -22.446 -4.052  0.5 34.74  ? 301 IJX A C2  1 
HETATM 9059 O  O1  . IJX E 3 .   ? 15.069  -22.008 -2.951  0.5 37.4   ? 301 IJX A O1  1 
HETATM 9060 BR BR1 . IJX E 3 .   ? 13.798  -26.26  -9.78   0.5 59.79  ? 301 IJX A BR1 1 
HETATM 9061 C  C4  . IJX F 3 .   ? -9.066  -22.723 24.291  1   95.29  ? 302 IJX A C4  1 
HETATM 9062 C  C5  . IJX F 3 .   ? -9.398  -21.718 23.388  1   108.49 ? 302 IJX A C5  1 
HETATM 9063 C  C6  . IJX F 3 .   ? -8.38   -21.033 22.722  1   132.31 ? 302 IJX A C6  1 
HETATM 9064 C  C7  . IJX F 3 .   ? -7.042  -21.343 22.946  1   107.57 ? 302 IJX A C7  1 
HETATM 9065 C  C8  . IJX F 3 .   ? -6.711  -22.349 23.85   1   95.59  ? 302 IJX A C8  1 
HETATM 9066 N  N1  . IJX F 3 .   ? -7.321  -24.067 25.389  1   117.41 ? 302 IJX A N1  1 
HETATM 9067 C  C3  . IJX F 3 .   ? -7.724  -23.065 24.488  1   107.19 ? 302 IJX A C3  1 
HETATM 9068 C  C1  . IJX F 3 .   ? -5.241  -24.787 24.26   1   102.25 ? 302 IJX A C1  1 
HETATM 9069 C  C2  . IJX F 3 .   ? -6.112  -24.664 25.491  1   116.85 ? 302 IJX A C2  1 
HETATM 9070 O  O1  . IJX F 3 .   ? -5.688  -24.961 26.552  1   119.85 ? 302 IJX A O1  1 
HETATM 9071 BR BR1 . IJX F 3 .   ? -8.801  -19.653 21.467  1   131.48 ? 302 IJX A BR1 1 
HETATM 9072 C  C4  A IJX G 3 .   ? -19.563 18.978  3.426   0.5 57.44  ? 501 IJX B C4  1 
HETATM 9073 C  C4  B IJX G 3 .   ? -12.95  17.324  0.019   0.5 76.94  ? 501 IJX B C4  1 
HETATM 9074 C  C5  A IJX G 3 .   ? -18.941 17.744  3.417   0.5 60.63  ? 501 IJX B C5  1 
HETATM 9075 C  C5  B IJX G 3 .   ? -13.303 16.337  0.916   0.5 72.1   ? 501 IJX B C5  1 
HETATM 9076 C  C6  A IJX G 3 .   ? -17.966 17.481  4.345   0.5 63.07  ? 501 IJX B C6  1 
HETATM 9077 C  C6  B IJX G 3 .   ? -14.266 16.597  1.862   0.5 70.4   ? 501 IJX B C6  1 
HETATM 9078 C  C7  A IJX G 3 .   ? -17.603 18.42   5.286   0.5 59.56  ? 501 IJX B C7  1 
HETATM 9079 C  C7  B IJX G 3 .   ? -14.892 17.826  1.933   0.5 69.63  ? 501 IJX B C7  1 
HETATM 9080 C  C8  A IJX G 3 .   ? -18.242 19.645  5.31    0.5 54.36  ? 501 IJX B C8  1 
HETATM 9081 C  C8  B IJX G 3 .   ? -14.547 18.812  1.023   0.5 71.55  ? 501 IJX B C8  1 
HETATM 9082 N  N1  A IJX G 3 .   ? -19.912 21.164  4.375   0.5 60.96  ? 501 IJX B N1  1 
HETATM 9083 N  N1  B IJX G 3 .   ? -13.132 19.48   -0.925  0.5 83.26  ? 501 IJX B N1  1 
HETATM 9084 C  C3  A IJX G 3 .   ? -19.22  19.933  4.372   0.5 57.37  ? 501 IJX B C3  1 
HETATM 9085 C  C3  B IJX G 3 .   ? -13.576 18.561  0.055   0.5 78.17  ? 501 IJX B C3  1 
HETATM 9086 C  C1  A IJX G 3 .   ? -20.951 20.752  2.243   0.5 50.17  ? 501 IJX B C1  1 
HETATM 9087 C  C1  B IJX G 3 .   ? -11.165 18.161  -1.439  0.5 84.23  ? 501 IJX B C1  1 
HETATM 9088 C  C2  A IJX G 3 .   ? -20.877 21.553  3.507   0.5 61.39  ? 501 IJX B C2  1 
HETATM 9089 C  C2  B IJX G 3 .   ? -12.081 19.311  -1.769  0.5 85.25  ? 501 IJX B C2  1 
HETATM 9090 O  O1  A IJX G 3 .   ? -21.687 22.445  3.758   0.5 64.04  ? 501 IJX B O1  1 
HETATM 9091 O  O1  B IJX G 3 .   ? -11.896 20.009  -2.758  0.5 75.33  ? 501 IJX B O1  1 
HETATM 9092 BR BR1 A IJX G 3 .   ? -17.115 15.783  4.331   0.5 74.82  ? 501 IJX B BR1 1 
HETATM 9093 BR BR1 B IJX G 3 .   ? -14.726 15.212  3.079   0.5 65.39  ? 501 IJX B BR1 1 
HETATM 9094 C  C4  . IJX H 3 .   ? -32.606 17.499  30.358  1   51.67  ? 501 IJX C C4  1 
HETATM 9095 C  C5  . IJX H 3 .   ? -32.519 16.234  30.911  1   55.37  ? 501 IJX C C5  1 
HETATM 9096 C  C6  . IJX H 3 .   ? -32.448 15.133  30.067  1   66.62  ? 501 IJX C C6  1 
HETATM 9097 C  C7  . IJX H 3 .   ? -32.475 15.271  28.683  1   52.68  ? 501 IJX C C7  1 
HETATM 9098 C  C8  . IJX H 3 .   ? -32.56  16.54   28.133  1   47.16  ? 501 IJX C C8  1 
HETATM 9099 N  N1  . IJX H 3 .   ? -32.701 18.976  28.48   1   53.24  ? 501 IJX C N1  1 
HETATM 9100 C  C3  . IJX H 3 .   ? -32.637 17.654  28.971  1   52.52  ? 501 IJX C C3  1 
HETATM 9101 C  C1  . IJX H 3 .   ? -32.253 20.887  27.096  1   48.08  ? 501 IJX C C1  1 
HETATM 9102 C  C2  . IJX H 3 .   ? -32.562 19.424  27.206  1   54.9   ? 501 IJX C C2  1 
HETATM 9103 O  O1  . IJX H 3 .   ? -32.719 18.723  26.205  1   52.2   ? 501 IJX C O1  1 
HETATM 9104 BR BR1 . IJX H 3 .   ? -32.285 13.396  30.834  1   67.72  ? 501 IJX C BR1 1 
HETATM 9105 O  O   . HOH I 4 .   ? 13.635  -31.904 -2.134  1   35.13  ? 401 HOH A O   1 
HETATM 9106 O  O   . HOH I 4 .   ? -19.715 -10.601 32.923  1   24.16  ? 402 HOH A O   1 
HETATM 9107 O  O   . HOH I 4 .   ? 4.912   -20.888 -15.016 1   43.77  ? 403 HOH A O   1 
HETATM 9108 O  O   . HOH I 4 .   ? -3.04   -20.777 17.295  1   50.5   ? 404 HOH A O   1 
HETATM 9109 O  O   . HOH I 4 .   ? -12.693 -28.422 -5.055  1   19.88  ? 405 HOH A O   1 
HETATM 9110 O  O   . HOH I 4 .   ? -13.471 -11.751 -2.928  1   29.26  ? 406 HOH A O   1 
HETATM 9111 O  O   . HOH I 4 .   ? -22.538 -15.621 17.593  1   40.69  ? 407 HOH A O   1 
HETATM 9112 O  O   . HOH I 4 .   ? -9.274  -51.699 3.226   1   30.17  ? 408 HOH A O   1 
HETATM 9113 O  O   . HOH I 4 .   ? -14.238 -45.952 -0.294  1   31.98  ? 409 HOH A O   1 
HETATM 9114 O  O   . HOH I 4 .   ? -14.995 -11.871 -5.053  1   26.12  ? 410 HOH A O   1 
HETATM 9115 O  O   . HOH I 4 .   ? -21.87  -17.866 31.668  1   15.03  ? 411 HOH A O   1 
HETATM 9116 O  O   . HOH I 4 .   ? -1.717  -24.114 9.212   1   51.47  ? 412 HOH A O   1 
HETATM 9117 O  O   . HOH I 4 .   ? -2.319  -44.654 22.032  1   47.88  ? 413 HOH A O   1 
HETATM 9118 O  O   . HOH I 4 .   ? 4.087   -20.834 -0.684  1   28.29  ? 414 HOH A O   1 
HETATM 9119 O  O   . HOH I 4 .   ? -2.952  -13.218 6.247   1   29.08  ? 415 HOH A O   1 
HETATM 9120 O  O   . HOH I 4 .   ? -21.352 -35.469 14.020  1   18.5   ? 416 HOH A O   1 
HETATM 9121 O  O   . HOH I 4 .   ? -0.033  -52.166 -3.139  1   52.82  ? 417 HOH A O   1 
HETATM 9122 O  O   . HOH I 4 .   ? -12.108 -12.579 -8.957  1   16.32  ? 418 HOH A O   1 
HETATM 9123 O  O   . HOH I 4 .   ? 4.978   -31.839 -14.906 1   43.84  ? 419 HOH A O   1 
HETATM 9124 O  O   . HOH I 4 .   ? -19.946 -15.118 42.704  1   21.04  ? 420 HOH A O   1 
HETATM 9125 O  O   . HOH I 4 .   ? -4.653  -9.114  8.356   1   27.07  ? 421 HOH A O   1 
HETATM 9126 O  O   . HOH I 4 .   ? -12.462 -10.19  3.108   1   18.62  ? 422 HOH A O   1 
HETATM 9127 O  O   . HOH I 4 .   ? -6.811  -12.922 8.564   1   29.57  ? 423 HOH A O   1 
HETATM 9128 O  O   . HOH I 4 .   ? -1.117  -24.656 -18.624 1   32.1   ? 424 HOH A O   1 
HETATM 9129 O  O   . HOH I 4 .   ? -19.575 -10.71  3.507   1   41.36  ? 425 HOH A O   1 
HETATM 9130 O  O   . HOH I 4 .   ? -9.697  -28.499 -13.777 1   45.63  ? 426 HOH A O   1 
HETATM 9131 O  O   . HOH I 4 .   ? -18.986 -24.56  19.463  1   23.43  ? 427 HOH A O   1 
HETATM 9132 O  O   . HOH I 4 .   ? -7.591  -16.481 -3.83   1   24     ? 428 HOH A O   1 
HETATM 9133 O  O   . HOH I 4 .   ? -11.274 -16.285 -9.178  1   38.34  ? 429 HOH A O   1 
HETATM 9134 O  O   . HOH I 4 .   ? -3.094  -4.866  12.013  1   24.11  ? 430 HOH A O   1 
HETATM 9135 O  O   . HOH I 4 .   ? 11.521  -38.464 -14.328 1   32.04  ? 431 HOH A O   1 
HETATM 9136 O  O   . HOH I 4 .   ? -13.151 -48.215 7.722   1   42.37  ? 432 HOH A O   1 
HETATM 9137 O  O   . HOH I 4 .   ? 2.045   -54.055 -1.09   1   18.67  ? 433 HOH A O   1 
HETATM 9138 O  O   . HOH I 4 .   ? -21.625 -28.365 7.993   1   37.37  ? 434 HOH A O   1 
HETATM 9139 O  O   . HOH I 4 .   ? -4.02   -19.081 -10.397 1   33.25  ? 435 HOH A O   1 
HETATM 9140 O  O   . HOH I 4 .   ? -21.982 -18.791 27.785  1   24.84  ? 436 HOH A O   1 
HETATM 9141 O  O   . HOH I 4 .   ? -3.438  -47.644 2.683   1   54.24  ? 437 HOH A O   1 
HETATM 9142 O  O   . HOH I 4 .   ? -4.727  -37.904 -4.588  1   41.21  ? 438 HOH A O   1 
HETATM 9143 O  O   . HOH I 4 .   ? -7.689  -23.743 -4.101  1   23.61  ? 439 HOH A O   1 
HETATM 9144 O  O   . HOH I 4 .   ? -2.995  -36.32  -5.551  1   36.55  ? 440 HOH A O   1 
HETATM 9145 O  O   . HOH I 4 .   ? 2.353   -29.198 13.12   1   33.23  ? 441 HOH A O   1 
HETATM 9146 O  O   . HOH I 4 .   ? -9.662  -46.712 -1.994  1   28.62  ? 442 HOH A O   1 
HETATM 9147 O  O   . HOH I 4 .   ? 2.052   -32.236 6.376   1   22.62  ? 443 HOH A O   1 
HETATM 9148 O  O   . HOH I 4 .   ? 1.358   -38.548 8.133   1   31.85  ? 444 HOH A O   1 
HETATM 9149 O  O   . HOH I 4 .   ? 0.376   -37.121 -9.827  1   25.5   ? 445 HOH A O   1 
HETATM 9150 O  O   . HOH I 4 .   ? 6.886   -28.638 -18.09  1   36.73  ? 446 HOH A O   1 
HETATM 9151 O  O   . HOH I 4 .   ? -16.596 -38.416 -3.033  1   39.65  ? 447 HOH A O   1 
HETATM 9152 O  O   . HOH I 4 .   ? -6.017  -24.34  6.132   1   23     ? 448 HOH A O   1 
HETATM 9153 O  O   . HOH I 4 .   ? -4.931  -15.53  -4.306  1   26.97  ? 449 HOH A O   1 
HETATM 9154 O  O   . HOH I 4 .   ? -3.48   -25.375 2.406   1   31.73  ? 450 HOH A O   1 
HETATM 9155 O  O   . HOH I 4 .   ? -21.137 -5.815  39.094  1   53.85  ? 451 HOH A O   1 
HETATM 9156 O  O   . HOH I 4 .   ? -7.374  -18.469 10.775  1   23.22  ? 452 HOH A O   1 
HETATM 9157 O  O   . HOH I 4 .   ? -14.048 -47.551 12.539  1   26.76  ? 453 HOH A O   1 
HETATM 9158 O  O   . HOH I 4 .   ? -12.492 -49.837 4.329   1   19.59  ? 454 HOH A O   1 
HETATM 9159 O  O   . HOH I 4 .   ? -14.702 -32.061 -6.1    1   48.61  ? 455 HOH A O   1 
HETATM 9160 O  O   . HOH I 4 .   ? -19.447 -21.48  17.347  1   34.83  ? 456 HOH A O   1 
HETATM 9161 O  O   . HOH I 4 .   ? -18.782 -16.223 30.803  1   24.34  ? 457 HOH A O   1 
HETATM 9162 O  O   . HOH I 4 .   ? -14.308 -26.982 -1.492  1   29.38  ? 458 HOH A O   1 
HETATM 9163 O  O   . HOH I 4 .   ? -2.395  -15.319 -3.336  1   18.01  ? 459 HOH A O   1 
HETATM 9164 O  O   . HOH I 4 .   ? -1.836  -43.804 -7.67   1   40.93  ? 460 HOH A O   1 
HETATM 9165 O  O   . HOH I 4 .   ? -2.997  -5.911  7.61    1   29.41  ? 461 HOH A O   1 
HETATM 9166 O  O   . HOH I 4 .   ? 5.657   -41.685 1.234   1   30.89  ? 462 HOH A O   1 
HETATM 9167 O  O   . HOH I 4 .   ? 0.285   -33.492 8.267   1   18.9   ? 463 HOH A O   1 
HETATM 9168 O  O   . HOH I 4 .   ? -8.216  -32.88  -12.954 1   26.4   ? 464 HOH A O   1 
HETATM 9169 O  O   . HOH I 4 .   ? -4.088  -8.54   5.665   1   25.65  ? 465 HOH A O   1 
HETATM 9170 O  O   . HOH I 4 .   ? -10     -18.663 18      1   52.47  ? 466 HOH A O   1 
HETATM 9171 O  O   . HOH I 4 .   ? -18.216 -18.179 17.368  1   43.78  ? 467 HOH A O   1 
HETATM 9172 O  O   . HOH I 4 .   ? -12.035 -10.85  5.664   1   24.01  ? 468 HOH A O   1 
HETATM 9173 O  O   . HOH I 4 .   ? -15.238 -44.114 -2.098  1   47.7   ? 469 HOH A O   1 
HETATM 9174 O  O   . HOH I 4 .   ? -16.048 -23.407 37.193  1   16.23  ? 470 HOH A O   1 
HETATM 9175 O  O   . HOH I 4 .   ? -17.401 -22.233 27.816  1   44.27  ? 471 HOH A O   1 
HETATM 9176 O  O   . HOH I 4 .   ? -16.64  -26.749 25.296  1   33.92  ? 472 HOH A O   1 
HETATM 9177 O  O   . HOH I 4 .   ? 1.26    -29.484 2.413   1   17.19  ? 473 HOH A O   1 
HETATM 9178 O  O   . HOH I 4 .   ? -9.02   -12.651 38.165  1   20.66  ? 474 HOH A O   1 
HETATM 9179 O  O   . HOH I 4 .   ? 3.431   -39.973 7.09    1   36.65  ? 475 HOH A O   1 
HETATM 9180 O  O   . HOH I 4 .   ? -12.343 -28.676 -2.532  1   24.63  ? 476 HOH A O   1 
HETATM 9181 O  O   . HOH I 4 .   ? -10.325 -10.899 -9.953  1   19.01  ? 477 HOH A O   1 
HETATM 9182 O  O   . HOH I 4 .   ? -22.64  -26.959 4.791   1   37.39  ? 478 HOH A O   1 
HETATM 9183 O  O   . HOH I 4 .   ? -4.898  -42.649 -5.597  1   40.62  ? 479 HOH A O   1 
HETATM 9184 O  O   . HOH I 4 .   ? -16.553 -32.47  -3.923  1   30.41  ? 480 HOH A O   1 
HETATM 9185 O  O   . HOH I 4 .   ? -7.937  -10.405 -7.992  1   17.87  ? 481 HOH A O   1 
HETATM 9186 O  O   . HOH I 4 .   ? 4.845   -21.947 8.193   1   27.52  ? 482 HOH A O   1 
HETATM 9187 O  O   . HOH I 4 .   ? -17.115 -4.18   26.057  1   43.45  ? 483 HOH A O   1 
HETATM 9188 O  O   . HOH I 4 .   ? -8.506  -48.677 16.259  1   23.13  ? 484 HOH A O   1 
HETATM 9189 O  O   . HOH I 4 .   ? -6.356  -25.348 -11.065 1   28.21  ? 485 HOH A O   1 
HETATM 9190 O  O   . HOH I 4 .   ? 6.94    -19.672 3.068   1   34.53  ? 486 HOH A O   1 
HETATM 9191 O  O   . HOH I 4 .   ? 13.89   -34.439 6.868   1   21.92  ? 487 HOH A O   1 
HETATM 9192 O  O   . HOH I 4 .   ? -26.872 -19.964 8.595   1   42.31  ? 488 HOH A O   1 
HETATM 9193 O  O   . HOH I 4 .   ? 4.341   -41.15  3.415   1   30.08  ? 489 HOH A O   1 
HETATM 9194 O  O   . HOH I 4 .   ? -19.144 -37.559 15.447  1   49.12  ? 490 HOH A O   1 
HETATM 9195 O  O   . HOH I 4 .   ? -11.1   -11.073 39.794  1   51.26  ? 491 HOH A O   1 
HETATM 9196 O  O   . HOH I 4 .   ? -22.224 -35.503 29.43   1   46.48  ? 492 HOH A O   1 
HETATM 9197 O  O   . HOH I 4 .   ? -23.463 -29.169 10.341  1   34.06  ? 493 HOH A O   1 
HETATM 9198 O  O   . HOH I 4 .   ? 10.365  -41.383 -9.825  1   27.2   ? 494 HOH A O   1 
HETATM 9199 O  O   . HOH I 4 .   ? -20.645 -16.129 28.364  1   43.83  ? 495 HOH A O   1 
HETATM 9200 O  O   . HOH I 4 .   ? -20.086 -29.098 22.007  1   38.57  ? 496 HOH A O   1 
HETATM 9201 O  O   . HOH I 4 .   ? -2.859  -7.588  12.254  1   30.03  ? 497 HOH A O   1 
HETATM 9202 O  O   . HOH I 4 .   ? -16.658 -43.744 14.829  1   28.45  ? 498 HOH A O   1 
HETATM 9203 O  O   . HOH I 4 .   ? 1.854   -50.561 2.421   1   32.48  ? 499 HOH A O   1 
HETATM 9204 O  O   . HOH I 4 .   ? 11.822  -22.283 -1.16   1   21.87  ? 500 HOH A O   1 
HETATM 9205 O  O   . HOH I 4 .   ? -16.469 -24.951 28.322  1   29.9   ? 501 HOH A O   1 
HETATM 9206 O  O   . HOH I 4 .   ? -20.335 -35.64  16.847  1   51.52  ? 502 HOH A O   1 
HETATM 9207 O  O   . HOH I 4 .   ? -3.509  -51.595 8.877   1   38.52  ? 503 HOH A O   1 
HETATM 9208 O  O   . HOH I 4 .   ? 11.154  -20.894 1.76    1   32.46  ? 504 HOH A O   1 
HETATM 9209 O  O   . HOH I 4 .   ? -19.307 -31.669 23.34   1   34.03  ? 505 HOH A O   1 
HETATM 9210 O  O   . HOH I 4 .   ? 2.644   -24.837 14.225  1   31.71  ? 506 HOH A O   1 
HETATM 9211 O  O   . HOH I 4 .   ? 10.545  -37.047 0.547   1   25.14  ? 507 HOH A O   1 
HETATM 9212 O  O   . HOH I 4 .   ? -6.071  -52.19  2.805   1   40.43  ? 508 HOH A O   1 
HETATM 9213 O  O   . HOH I 4 .   ? -4.161  -35.834 -8.058  1   18.4   ? 509 HOH A O   1 
HETATM 9214 O  O   . HOH I 4 .   ? -6.142  -6.549  -1.907  1   24.26  ? 510 HOH A O   1 
HETATM 9215 O  O   . HOH I 4 .   ? -15.789 -41.597 -3.044  1   26.54  ? 511 HOH A O   1 
HETATM 9216 O  O   . HOH I 4 .   ? 9.869   -21.897 -7.943  1   37.18  ? 512 HOH A O   1 
HETATM 9217 O  O   . HOH I 4 .   ? -16.339 -46.058 13.667  1   30.74  ? 513 HOH A O   1 
HETATM 9218 O  O   . HOH I 4 .   ? -3.175  -51.505 1.899   1   43.9   ? 514 HOH A O   1 
HETATM 9219 O  O   . HOH I 4 .   ? -1.764  -20.541 38.227  1   54.67  ? 515 HOH A O   1 
HETATM 9220 O  O   . HOH I 4 .   ? -1.15   -17.382 -3.414  1   32.79  ? 516 HOH A O   1 
HETATM 9221 O  O   . HOH I 4 .   ? -0.699  -11.454 -2.8    1   29.79  ? 517 HOH A O   1 
HETATM 9222 O  O   . HOH I 4 .   ? -18.137 -24.738 31.962  1   32.75  ? 518 HOH A O   1 
HETATM 9223 O  O   . HOH I 4 .   ? -15.888 -47.575 7.113   1   65.2   ? 519 HOH A O   1 
HETATM 9224 O  O   . HOH I 4 .   ? -2.007  -8.91   8.599   1   32.26  ? 520 HOH A O   1 
HETATM 9225 O  O   . HOH I 4 .   ? 0.784   -19.03  8.416   1   40.24  ? 521 HOH A O   1 
HETATM 9226 O  O   . HOH I 4 .   ? -0.439  -53.554 -0.832  1   47.56  ? 522 HOH A O   1 
HETATM 9227 O  O   . HOH I 4 .   ? 5.205   -25.942 9.504   1   28.25  ? 523 HOH A O   1 
HETATM 9228 O  O   . HOH I 4 .   ? 13.205  -40.991 -6.750  1   46.93  ? 524 HOH A O   1 
HETATM 9229 O  O   . HOH I 4 .   ? -3.974  -11.719 8.753   1   34.34  ? 525 HOH A O   1 
HETATM 9230 O  O   . HOH I 4 .   ? -15.915 -10.263 0.13    1   28.66  ? 526 HOH A O   1 
HETATM 9231 O  O   . HOH I 4 .   ? -0.159  -14.004 6.302   1   28.02  ? 527 HOH A O   1 
HETATM 9232 O  O   . HOH I 4 .   ? 4.09    -26.643 12.28   1   32.17  ? 528 HOH A O   1 
HETATM 9233 O  O   . HOH I 4 .   ? 6.915   -40.122 13.637  1   45.6   ? 529 HOH A O   1 
HETATM 9234 O  O   . HOH I 4 .   ? -27.113 -21.7   11.002  1   34.17  ? 530 HOH A O   1 
HETATM 9235 O  O   . HOH I 4 .   ? 12.945  -34.728 9.697   1   39.72  ? 531 HOH A O   1 
HETATM 9236 O  O   . HOH J 4 .   ? -30.208 -21.713 -0.363  1   38.5   ? 601 HOH B O   1 
HETATM 9237 O  O   . HOH J 4 .   ? -37.348 -7.17   -6.36   1   36.96  ? 602 HOH B O   1 
HETATM 9238 O  O   . HOH J 4 .   ? -16.813 -7.695  -3.806  1   42.93  ? 603 HOH B O   1 
HETATM 9239 O  O   . HOH J 4 .   ? -32.12  -10.188 0.897   1   24.8   ? 604 HOH B O   1 
HETATM 9240 O  O   . HOH J 4 .   ? -24.829 -4.859  3.627   1   38.01  ? 605 HOH B O   1 
HETATM 9241 O  O   . HOH J 4 .   ? -34.486 -2.664  -20.186 1   25.2   ? 606 HOH B O   1 
HETATM 9242 O  O   . HOH J 4 .   ? -4.119  -4.035  -0.787  1   30.38  ? 607 HOH B O   1 
HETATM 9243 O  O   . HOH J 4 .   ? -29.714 22.024  11.283  1   50.04  ? 608 HOH B O   1 
HETATM 9244 O  O   . HOH J 4 .   ? -5.68   -6.473  6.372   1   28.09  ? 609 HOH B O   1 
HETATM 9245 O  O   . HOH J 4 .   ? -19.345 -12.744 -0.538  1   25.82  ? 610 HOH B O   1 
HETATM 9246 O  O   . HOH J 4 .   ? -15.004 -27.437 1.178   1   12.33  ? 611 HOH B O   1 
HETATM 9247 O  O   . HOH J 4 .   ? -32.439 8.077   1.783   1   38.05  ? 612 HOH B O   1 
HETATM 9248 O  O   . HOH J 4 .   ? -26.323 -18.943 -9.473  1   31.67  ? 613 HOH B O   1 
HETATM 9249 O  O   . HOH J 4 .   ? -21.247 5.034   -19.545 1   23.09  ? 614 HOH B O   1 
HETATM 9250 O  O   . HOH J 4 .   ? -17.84  -0.783  -7.62   1   45.02  ? 615 HOH B O   1 
HETATM 9251 O  O   . HOH J 4 .   ? -25.784 10.958  -0.393  1   21.82  ? 616 HOH B O   1 
HETATM 9252 O  O   . HOH J 4 .   ? -25.254 1.753   2.227   1   44.11  ? 617 HOH B O   1 
HETATM 9253 O  O   . HOH J 4 .   ? -28.613 9.799   -8.198  1   18.5   ? 618 HOH B O   1 
HETATM 9254 O  O   . HOH J 4 .   ? -17.768 -12.872 -11.451 1   36.17  ? 619 HOH B O   1 
HETATM 9255 O  O   . HOH J 4 .   ? -27.059 12.829  -2.924  1   23.45  ? 620 HOH B O   1 
HETATM 9256 O  O   . HOH J 4 .   ? -30.444 -18.212 -2.296  1   35.31  ? 621 HOH B O   1 
HETATM 9257 O  O   . HOH J 4 .   ? -26.648 11.136  -11.746 1   26.9   ? 622 HOH B O   1 
HETATM 9258 O  O   . HOH J 4 .   ? -40.378 -4.108  -6.231  1   34.12  ? 623 HOH B O   1 
HETATM 9259 O  O   . HOH J 4 .   ? -13.489 -10.808 -0.161  1   34.73  ? 624 HOH B O   1 
HETATM 9260 O  O   . HOH J 4 .   ? -36.462 -13.345 -3.814  1   24.3   ? 625 HOH B O   1 
HETATM 9261 O  O   . HOH J 4 .   ? -12.211 4.038   -5.685  1   24.83  ? 626 HOH B O   1 
HETATM 9262 O  O   . HOH J 4 .   ? -20.103 17.648  -14.341 1   52.72  ? 627 HOH B O   1 
HETATM 9263 O  O   . HOH J 4 .   ? -8.297  2.227   17.242  1   32.83  ? 628 HOH B O   1 
HETATM 9264 O  O   . HOH J 4 .   ? -11.739 9.751   -9.433  1   36.44  ? 629 HOH B O   1 
HETATM 9265 O  O   . HOH J 4 .   ? -29.009 11.673  14.231  1   25.03  ? 630 HOH B O   1 
HETATM 9266 O  O   . HOH J 4 .   ? -30.743 5.328   -26.496 1   34.3   ? 631 HOH B O   1 
HETATM 9267 O  O   . HOH J 4 .   ? -19.962 -13.106 -3.44   1   26.91  ? 632 HOH B O   1 
HETATM 9268 O  O   . HOH J 4 .   ? -30.203 -11.976 -4.873  1   25.68  ? 633 HOH B O   1 
HETATM 9269 O  O   . HOH J 4 .   ? -28.549 -23.293 -0.299  1   35.74  ? 634 HOH B O   1 
HETATM 9270 O  O   . HOH J 4 .   ? -32.753 -16.616 -3.466  1   29.16  ? 635 HOH B O   1 
HETATM 9271 O  O   . HOH J 4 .   ? -20.883 8.339   -17.487 1   19.85  ? 636 HOH B O   1 
HETATM 9272 O  O   . HOH J 4 .   ? -25.94  20.331  2.261   1   20.53  ? 637 HOH B O   1 
HETATM 9273 O  O   . HOH J 4 .   ? -32.351 16.933  9.13    1   28.01  ? 638 HOH B O   1 
HETATM 9274 O  O   . HOH J 4 .   ? -7.848  18.009  15.139  1   29.72  ? 639 HOH B O   1 
HETATM 9275 O  O   . HOH J 4 .   ? -16.116 -8.369  1.941   1   19.75  ? 640 HOH B O   1 
HETATM 9276 O  O   . HOH J 4 .   ? -6.108  -3.398  -3.639  1   23.44  ? 641 HOH B O   1 
HETATM 9277 O  O   . HOH J 4 .   ? -16.127 14.849  -8.014  1   31.06  ? 642 HOH B O   1 
HETATM 9278 O  O   . HOH J 4 .   ? 4.203   -9.479  -1.759  1   32.92  ? 643 HOH B O   1 
HETATM 9279 O  O   . HOH J 4 .   ? -30.645 -19.501 -4.985  1   36.34  ? 644 HOH B O   1 
HETATM 9280 O  O   . HOH J 4 .   ? -25.603 4.098   18.959  1   29.82  ? 645 HOH B O   1 
HETATM 9281 O  O   . HOH J 4 .   ? -15.924 16.633  8.1     1   31.54  ? 646 HOH B O   1 
HETATM 9282 O  O   . HOH J 4 .   ? -38.494 4.316   -8.72   1   22.83  ? 647 HOH B O   1 
HETATM 9283 O  O   . HOH J 4 .   ? -21.621 11.483  -11.63  1   34.72  ? 648 HOH B O   1 
HETATM 9284 O  O   . HOH J 4 .   ? -15.381 -9.071  -22.627 1   49.55  ? 649 HOH B O   1 
HETATM 9285 O  O   . HOH J 4 .   ? -19.919 -22.242 -9.386  1   42.29  ? 650 HOH B O   1 
HETATM 9286 O  O   . HOH J 4 .   ? -6.026  14.213  19.528  1   30.4   ? 651 HOH B O   1 
HETATM 9287 O  O   . HOH J 4 .   ? -29.403 -12.49  -20.517 1   24.72  ? 652 HOH B O   1 
HETATM 9288 O  O   . HOH J 4 .   ? -30.406 15.969  3.078   1   29.67  ? 653 HOH B O   1 
HETATM 9289 O  O   . HOH J 4 .   ? -26.686 5.084   -1.3    1   45.25  ? 654 HOH B O   1 
HETATM 9290 O  O   . HOH J 4 .   ? -17.121 -10.555 -4.759  1   36.91  ? 655 HOH B O   1 
HETATM 9291 O  O   . HOH J 4 .   ? -18.072 -8.612  3.795   1   24.71  ? 656 HOH B O   1 
HETATM 9292 O  O   . HOH J 4 .   ? -31.358 10.121  3.169   1   37     ? 657 HOH B O   1 
HETATM 9293 O  O   . HOH J 4 .   ? -23.448 -2.895  1.803   1   42.07  ? 658 HOH B O   1 
HETATM 9294 O  O   . HOH J 4 .   ? -24.345 -17.265 -9.11   1   39.12  ? 659 HOH B O   1 
HETATM 9295 O  O   . HOH J 4 .   ? -23.205 20.316  1.013   1   28.05  ? 660 HOH B O   1 
HETATM 9296 O  O   . HOH J 4 .   ? -1.5    12.999  13.805  1   22.04  ? 661 HOH B O   1 
HETATM 9297 O  O   . HOH J 4 .   ? -27.411 -3.856  3.435   1   38.77  ? 662 HOH B O   1 
HETATM 9298 O  O   . HOH J 4 .   ? -24.318 9.38    -8.352  1   21.6   ? 663 HOH B O   1 
HETATM 9299 O  O   . HOH J 4 .   ? -18.758 10.208  -8.124  1   30.09  ? 664 HOH B O   1 
HETATM 9300 O  O   . HOH J 4 .   ? -11.21  -3.547  -7.019  1   34.44  ? 665 HOH B O   1 
HETATM 9301 O  O   . HOH J 4 .   ? -24.452 16.646  -4.042  1   31.81  ? 666 HOH B O   1 
HETATM 9302 O  O   . HOH J 4 .   ? -22.966 -10.256 -20.466 1   28.9   ? 667 HOH B O   1 
HETATM 9303 O  O   . HOH J 4 .   ? -35.188 -8.576  -1.38   1   19.34  ? 668 HOH B O   1 
HETATM 9304 O  O   . HOH J 4 .   ? -35.269 2.011   8.008   1   48.24  ? 669 HOH B O   1 
HETATM 9305 O  O   . HOH J 4 .   ? -7.844  -22.348 -6.716  1   45.87  ? 670 HOH B O   1 
HETATM 9306 O  O   . HOH J 4 .   ? -19.186 10.25   -10.749 1   35.22  ? 671 HOH B O   1 
HETATM 9307 O  O   . HOH J 4 .   ? -17.696 -11.757 2.012   1   35.55  ? 672 HOH B O   1 
HETATM 9308 O  O   . HOH J 4 .   ? -2.516  12.156  17.567  1   32.95  ? 673 HOH B O   1 
HETATM 9309 O  O   . HOH J 4 .   ? -23.458 -25.634 -8.275  1   30.77  ? 674 HOH B O   1 
HETATM 9310 O  O   . HOH J 4 .   ? -24.12  -24.144 -4.394  1   30.3   ? 675 HOH B O   1 
HETATM 9311 O  O   . HOH J 4 .   ? -27.724 6.048   19.676  1   21.17  ? 676 HOH B O   1 
HETATM 9312 O  O   . HOH J 4 .   ? -29.523 9.007   13.128  1   36.89  ? 677 HOH B O   1 
HETATM 9313 O  O   . HOH J 4 .   ? -22.665 -1.921  -1.308  1   37.41  ? 678 HOH B O   1 
HETATM 9314 O  O   . HOH J 4 .   ? -24.934 -24.43  -1.737  1   23.94  ? 679 HOH B O   1 
HETATM 9315 O  O   . HOH J 4 .   ? -20.193 -2.845  21.302  1   30.6   ? 680 HOH B O   1 
HETATM 9316 O  O   . HOH J 4 .   ? -37.893 -10.783 -15.533 1   16.29  ? 681 HOH B O   1 
HETATM 9317 O  O   . HOH J 4 .   ? -13.056 -5.372  -5.209  1   22.27  ? 682 HOH B O   1 
HETATM 9318 O  O   . HOH J 4 .   ? -1.148  5.273   18.878  1   52.99  ? 683 HOH B O   1 
HETATM 9319 O  O   . HOH J 4 .   ? -25.268 -26.273 4.055   1   26.08  ? 684 HOH B O   1 
HETATM 9320 O  O   . HOH J 4 .   ? -20.753 -10.622 -25.262 1   32.57  ? 685 HOH B O   1 
HETATM 9321 O  O   . HOH J 4 .   ? -6.947  -20.764 -10.085 1   32.49  ? 686 HOH B O   1 
HETATM 9322 O  O   . HOH J 4 .   ? -25.428 -2.318  12.478  1   34.15  ? 687 HOH B O   1 
HETATM 9323 O  O   . HOH J 4 .   ? -34.733 -3.56   -1.655  1   29.51  ? 688 HOH B O   1 
HETATM 9324 O  O   . HOH J 4 .   ? -23.427 8.786   -18.09  1   20.37  ? 689 HOH B O   1 
HETATM 9325 O  O   . HOH J 4 .   ? -21.755 10.79   -8.303  1   18.39  ? 690 HOH B O   1 
HETATM 9326 O  O   . HOH J 4 .   ? -12.271 -22.043 -10.833 1   22.08  ? 691 HOH B O   1 
HETATM 9327 O  O   . HOH J 4 .   ? -22.248 -27.945 -7.361  1   30.36  ? 692 HOH B O   1 
HETATM 9328 O  O   . HOH J 4 .   ? -36.808 -2.233  -6.873  1   34.25  ? 693 HOH B O   1 
HETATM 9329 O  O   . HOH J 4 .   ? -29.078 17.105  0.904   1   24.92  ? 694 HOH B O   1 
HETATM 9330 O  O   . HOH J 4 .   ? -18.91  21.134  13.083  1   16.89  ? 695 HOH B O   1 
HETATM 9331 O  O   . HOH J 4 .   ? -21.833 3.599   -26.332 1   19.15  ? 696 HOH B O   1 
HETATM 9332 O  O   . HOH J 4 .   ? -25.947 8.055   19.789  1   16.68  ? 697 HOH B O   1 
HETATM 9333 O  O   . HOH J 4 .   ? -21.44  -0.937  -25.991 1   22.98  ? 698 HOH B O   1 
HETATM 9334 O  O   . HOH J 4 .   ? -19.954 -9.347  10.77   1   36.26  ? 699 HOH B O   1 
HETATM 9335 O  O   . HOH J 4 .   ? -31.126 -17.71  -18.446 1   23.69  ? 700 HOH B O   1 
HETATM 9336 O  O   . HOH J 4 .   ? 0.699   -11.143 -0.534  1   29.12  ? 701 HOH B O   1 
HETATM 9337 O  O   . HOH J 4 .   ? -13.127 18.691  13.662  1   29.87  ? 702 HOH B O   1 
HETATM 9338 O  O   . HOH J 4 .   ? -11.069 18.176  14.94   1   14.23  ? 703 HOH B O   1 
HETATM 9339 O  O   . HOH J 4 .   ? -13.832 17.894  7.489   1   24.62  ? 704 HOH B O   1 
HETATM 9340 O  O   . HOH J 4 .   ? -25.867 16.385  -8.028  1   19.31  ? 705 HOH B O   1 
HETATM 9341 O  O   . HOH J 4 .   ? -27.367 20.841  7.881   1   26.26  ? 706 HOH B O   1 
HETATM 9342 O  O   . HOH J 4 .   ? -32.755 -15.958 -20.245 1   26.19  ? 707 HOH B O   1 
HETATM 9343 O  O   . HOH J 4 .   ? -22.791 -0.507  0.724   1   44.91  ? 708 HOH B O   1 
HETATM 9344 O  O   . HOH J 4 .   ? -19.506 -5.654  -26.433 1   29.77  ? 709 HOH B O   1 
HETATM 9345 O  O   . HOH J 4 .   ? -26.726 25.461  7.842   1   20.69  ? 710 HOH B O   1 
HETATM 9346 O  O   . HOH J 4 .   ? -18.484 -15.192 -16.268 1   32.58  ? 711 HOH B O   1 
HETATM 9347 O  O   . HOH J 4 .   ? -32.518 -11.41  -23.487 1   23.43  ? 712 HOH B O   1 
HETATM 9348 O  O   . HOH J 4 .   ? -31.603 11.49   -11.178 1   39.38  ? 713 HOH B O   1 
HETATM 9349 O  O   . HOH J 4 .   ? -16.576 -26.297 -3.675  1   8.88   ? 714 HOH B O   1 
HETATM 9350 O  O   . HOH J 4 .   ? -23.495 -20.237 -13.057 1   25.8   ? 715 HOH B O   1 
HETATM 9351 O  O   . HOH J 4 .   ? -30.077 -21.049 -10.592 1   31.51  ? 716 HOH B O   1 
HETATM 9352 O  O   . HOH J 4 .   ? -28.405 -19.273 5.808   1   43.73  ? 717 HOH B O   1 
HETATM 9353 O  O   . HOH J 4 .   ? -25.92  -20.693 -14.161 1   33.31  ? 718 HOH B O   1 
HETATM 9354 O  O   . HOH J 4 .   ? -26.834 15.518  -3.107  1   30.26  ? 719 HOH B O   1 
HETATM 9355 O  O   . HOH J 4 .   ? -16.994 21.015  7.731   1   48     ? 720 HOH B O   1 
HETATM 9356 O  O   . HOH J 4 .   ? -23.81  10.093  -10.937 1   29.07  ? 721 HOH B O   1 
HETATM 9357 O  O   . HOH J 4 .   ? -34.692 -9.694  1.203   1   36.86  ? 722 HOH B O   1 
HETATM 9358 O  O   . HOH J 4 .   ? -27.727 -1.444  2.382   1   31.84  ? 723 HOH B O   1 
HETATM 9359 O  O   . HOH J 4 .   ? -37.564 -9.589  -1.797  1   33.52  ? 724 HOH B O   1 
HETATM 9360 O  O   . HOH J 4 .   ? -15.732 -11.326 -10.586 1   32.98  ? 725 HOH B O   1 
HETATM 9361 O  O   . HOH J 4 .   ? -27.939 -21.89  -12.981 1   37.38  ? 726 HOH B O   1 
HETATM 9362 O  O   . HOH K 4 .   ? -19.654 1.281   44.468  1   25.3   ? 601 HOH C O   1 
HETATM 9363 O  O   . HOH K 4 .   ? -27.138 1.349   24.018  1   44.35  ? 602 HOH C O   1 
HETATM 9364 O  O   . HOH K 4 .   ? -28.3   15.528  21.323  1   24.97  ? 603 HOH C O   1 
HETATM 9365 O  O   . HOH K 4 .   ? -31.438 -5.159  51.612  1   18.29  ? 604 HOH C O   1 
HETATM 9366 O  O   . HOH K 4 .   ? -59.27  -2.192  36.341  1   53.99  ? 605 HOH C O   1 
HETATM 9367 O  O   . HOH K 4 .   ? -18.534 3.989   26.18   1   42.74  ? 606 HOH C O   1 
HETATM 9368 O  O   . HOH K 4 .   ? -52.752 13.551  36.726  1   20.71  ? 607 HOH C O   1 
HETATM 9369 O  O   . HOH K 4 .   ? -50.742 6.037   19.119  1   27.26  ? 608 HOH C O   1 
HETATM 9370 O  O   . HOH K 4 .   ? -51.161 24.199  35.221  1   20.89  ? 609 HOH C O   1 
HETATM 9371 O  O   . HOH K 4 .   ? -43.022 4.689   42.036  1   41.31  ? 610 HOH C O   1 
HETATM 9372 O  O   . HOH K 4 .   ? -57.906 7.47    35.568  1   29.17  ? 611 HOH C O   1 
HETATM 9373 O  O   . HOH K 4 .   ? -45.533 -2.57   35.365  1   21.17  ? 612 HOH C O   1 
HETATM 9374 O  O   . HOH K 4 .   ? -35.126 4.903   22.947  1   42.63  ? 613 HOH C O   1 
HETATM 9375 O  O   . HOH K 4 .   ? -57.584 6.803   41.503  1   48.41  ? 614 HOH C O   1 
HETATM 9376 O  O   . HOH K 4 .   ? -49.141 12.928  34.135  1   29.31  ? 615 HOH C O   1 
HETATM 9377 O  O   . HOH K 4 .   ? -66.831 8.535   50.732  1   43.65  ? 616 HOH C O   1 
HETATM 9378 O  O   . HOH K 4 .   ? -57.25  7.899   27.454  1   16.34  ? 617 HOH C O   1 
HETATM 9379 O  O   . HOH K 4 .   ? -42.413 0.973   42.623  1   29.25  ? 618 HOH C O   1 
HETATM 9380 O  O   . HOH K 4 .   ? -28.033 -1.622  27.657  1   29.98  ? 619 HOH C O   1 
HETATM 9381 O  O   . HOH K 4 .   ? -37.451 11.399  19.586  1   42.52  ? 620 HOH C O   1 
HETATM 9382 O  O   . HOH K 4 .   ? -44.091 24.172  16.841  1   21.38  ? 621 HOH C O   1 
HETATM 9383 O  O   . HOH K 4 .   ? -40.111 2.182   41.191  1   35.11  ? 622 HOH C O   1 
HETATM 9384 O  O   . HOH K 4 .   ? -40.523 34.402  34.657  1   19.93  ? 623 HOH C O   1 
HETATM 9385 O  O   . HOH K 4 .   ? -22.872 11.065  18.319  1   15.77  ? 624 HOH C O   1 
HETATM 9386 O  O   . HOH K 4 .   ? -54.261 1.825   38.558  1   20.82  ? 625 HOH C O   1 
HETATM 9387 O  O   . HOH K 4 .   ? -24.546 -0.149  48.419  1   8.65   ? 626 HOH C O   1 
HETATM 9388 O  O   . HOH K 4 .   ? -43.993 7.178   43.686  1   43.82  ? 627 HOH C O   1 
HETATM 9389 O  O   . HOH K 4 .   ? -28.514 18      20.5    1   25.53  ? 628 HOH C O   1 
HETATM 9390 O  O   . HOH K 4 .   ? -54.959 8.88    26.121  1   29.42  ? 629 HOH C O   1 
HETATM 9391 O  O   . HOH K 4 .   ? -54.817 17.525  52.322  1   36.87  ? 630 HOH C O   1 
HETATM 9392 O  O   . HOH K 4 .   ? -52.273 23.051  37.597  1   29.72  ? 631 HOH C O   1 
HETATM 9393 O  O   . HOH K 4 .   ? -38.266 8.311   21.441  1   38.61  ? 632 HOH C O   1 
HETATM 9394 O  O   . HOH K 4 .   ? -54.637 18.886  39.018  1   22.08  ? 633 HOH C O   1 
HETATM 9395 O  O   . HOH K 4 .   ? -31.453 10.426  39.676  1   55.05  ? 634 HOH C O   1 
HETATM 9396 O  O   . HOH K 4 .   ? -35.067 13.211  32.736  1   46.97  ? 635 HOH C O   1 
HETATM 9397 O  O   . HOH K 4 .   ? -36.371 6.923   23.57   1   33.22  ? 636 HOH C O   1 
HETATM 9398 O  O   . HOH K 4 .   ? -42.271 9.468   34.476  1   29.84  ? 637 HOH C O   1 
HETATM 9399 O  O   . HOH K 4 .   ? -29.11  20.495  21.283  1   50.59  ? 638 HOH C O   1 
HETATM 9400 O  O   . HOH K 4 .   ? -54.652 -4.511  41.942  1   24.91  ? 639 HOH C O   1 
HETATM 9401 O  O   . HOH K 4 .   ? -26.753 10.06   18.396  1   23.1   ? 640 HOH C O   1 
HETATM 9402 O  O   . HOH K 4 .   ? -53.834 23.526  53.1    1   20.6   ? 641 HOH C O   1 
HETATM 9403 O  O   . HOH K 4 .   ? -57.451 -5.287  37.749  1   54.02  ? 642 HOH C O   1 
HETATM 9404 O  O   . HOH K 4 .   ? -39.384 0.1     44.145  1   18.65  ? 643 HOH C O   1 
HETATM 9405 O  O   . HOH K 4 .   ? -62.439 -4.437  41.309  1   51.81  ? 644 HOH C O   1 
HETATM 9406 O  O   . HOH K 4 .   ? -52.663 -6.465  28.912  1   44.34  ? 645 HOH C O   1 
HETATM 9407 O  O   . HOH K 4 .   ? -47.986 -4.352  43.312  1   17.42  ? 646 HOH C O   1 
HETATM 9408 O  O   . HOH K 4 .   ? -59.989 5.415   36.811  1   22.08  ? 647 HOH C O   1 
HETATM 9409 O  O   . HOH K 4 .   ? -31.076 1.056   44.269  1   68.68  ? 648 HOH C O   1 
HETATM 9410 O  O   . HOH K 4 .   ? -45.921 16.921  44.148  1   52.24  ? 649 HOH C O   1 
HETATM 9411 O  O   . HOH K 4 .   ? -43.462 -0.993  34.71   1   22.94  ? 650 HOH C O   1 
HETATM 9412 O  O   . HOH K 4 .   ? -58.776 10.095  29.126  1   30.78  ? 651 HOH C O   1 
HETATM 9413 O  O   . HOH K 4 .   ? -25.782 2.998   21.964  1   42.25  ? 652 HOH C O   1 
HETATM 9414 O  O   . HOH K 4 .   ? -23.001 10.756  21.84   1   22.85  ? 653 HOH C O   1 
HETATM 9415 O  O   . HOH K 4 .   ? -36.902 17.069  34.021  1   44.47  ? 654 HOH C O   1 
HETATM 9416 O  O   . HOH K 4 .   ? -16.842 1.559   38.292  1   42.11  ? 655 HOH C O   1 
HETATM 9417 O  O   . HOH K 4 .   ? -25.899 18.256  19.53   1   21.57  ? 656 HOH C O   1 
HETATM 9418 O  O   . HOH K 4 .   ? -54.144 2.612   41.335  1   36.02  ? 657 HOH C O   1 
HETATM 9419 O  O   . HOH K 4 .   ? -21.552 -0.219  28.8    1   18.14  ? 658 HOH C O   1 
HETATM 9420 O  O   . HOH K 4 .   ? -15.214 15.511  31.061  1   27.04  ? 659 HOH C O   1 
HETATM 9421 O  O   . HOH K 4 .   ? -48.035 -4.928  31.856  1   56.32  ? 660 HOH C O   1 
HETATM 9422 O  O   . HOH K 4 .   ? -35.543 0.178   43.906  1   21.66  ? 661 HOH C O   1 
HETATM 9423 O  O   . HOH K 4 .   ? -31.028 12.553  18.767  1   33.8   ? 662 HOH C O   1 
HETATM 9424 O  O   . HOH K 4 .   ? -43.323 14.086  41.267  1   62.11  ? 663 HOH C O   1 
HETATM 9425 O  O   . HOH K 4 .   ? -52.106 16.672  51.66   1   45.97  ? 664 HOH C O   1 
HETATM 9426 O  O   . HOH K 4 .   ? -49.396 2.84    46.699  1   18.37  ? 665 HOH C O   1 
HETATM 9427 O  O   . HOH K 4 .   ? -62.376 3.469   43.961  1   40.38  ? 666 HOH C O   1 
HETATM 9428 O  O   . HOH K 4 .   ? -38.527 9.513   16.072  1   27.2   ? 667 HOH C O   1 
HETATM 9429 O  O   . HOH K 4 .   ? -13.458 5.327   21.402  1   18.04  ? 668 HOH C O   1 
HETATM 9430 O  O   . HOH K 4 .   ? -23.694 0.11    24.056  1   49     ? 669 HOH C O   1 
HETATM 9431 O  O   . HOH K 4 .   ? -62.336 9.922   24.117  1   27.52  ? 670 HOH C O   1 
HETATM 9432 O  O   . HOH K 4 .   ? -35.283 11.971  30.168  1   35.37  ? 671 HOH C O   1 
HETATM 9433 O  O   . HOH K 4 .   ? -56.994 27.015  41.405  1   48.13  ? 672 HOH C O   1 
HETATM 9434 O  O   . HOH K 4 .   ? -22.514 1.064   25.884  1   48.42  ? 673 HOH C O   1 
HETATM 9435 O  O   . HOH K 4 .   ? -27.999 15.601  17.894  1   26.02  ? 674 HOH C O   1 
HETATM 9436 O  O   . HOH K 4 .   ? -22.367 1.799   22.078  1   31.35  ? 675 HOH C O   1 
HETATM 9437 O  O   . HOH K 4 .   ? -58.798 5.615   26.606  1   8.18   ? 676 HOH C O   1 
HETATM 9438 O  O   . HOH K 4 .   ? -24.178 8.526   22.263  1   22.95  ? 677 HOH C O   1 
HETATM 9439 O  O   . HOH L 4 .   ? -25.132 -25.212 31.588  1   30.04  ? 501 HOH D O   1 
HETATM 9440 O  O   . HOH L 4 .   ? -48.962 -31.955 34.761  1   47.52  ? 502 HOH D O   1 
HETATM 9441 O  O   . HOH L 4 .   ? -28.888 -29.659 29.417  1   18.02  ? 503 HOH D O   1 
HETATM 9442 O  O   . HOH L 4 .   ? -59.428 -9.138  32.836  1   52.97  ? 504 HOH D O   1 
HETATM 9443 O  O   . HOH L 4 .   ? -46.478 -30.762 31.409  1   15.68  ? 505 HOH D O   1 
HETATM 9444 O  O   . HOH L 4 .   ? -26.031 -31.465 37.381  1   36.66  ? 506 HOH D O   1 
HETATM 9445 O  O   . HOH L 4 .   ? -38.651 -27.055 33.06   1   22.63  ? 507 HOH D O   1 
HETATM 9446 O  O   . HOH L 4 .   ? -46.439 -17.526 43.474  1   29.12  ? 508 HOH D O   1 
HETATM 9447 O  O   . HOH L 4 .   ? -51.376 -24.884 19.554  1   55.46  ? 509 HOH D O   1 
HETATM 9448 O  O   . HOH L 4 .   ? -45.839 -6.431  33.267  1   19.27  ? 510 HOH D O   1 
HETATM 9449 O  O   . HOH L 4 .   ? -36.018 -4.315  46.148  1   34.57  ? 511 HOH D O   1 
HETATM 9450 O  O   . HOH L 4 .   ? -47.926 -7.975  45.295  1   25.31  ? 512 HOH D O   1 
HETATM 9451 O  O   . HOH L 4 .   ? -42.721 -12.219 26.163  1   61.1   ? 513 HOH D O   1 
HETATM 9452 O  O   . HOH L 4 .   ? -27.006 -4.583  40.906  1   40.13  ? 514 HOH D O   1 
HETATM 9453 O  O   . HOH L 4 .   ? -28.428 -23.506 42.151  1   22.25  ? 515 HOH D O   1 
HETATM 9454 O  O   . HOH L 4 .   ? -50.048 -5.191  28.843  1   28.44  ? 516 HOH D O   1 
HETATM 9455 O  O   . HOH L 4 .   ? -43.332 -28.581 44.809  1   39.41  ? 517 HOH D O   1 
HETATM 9456 O  O   . HOH L 4 .   ? -22.538 -16.373 26.527  1   24.61  ? 518 HOH D O   1 
HETATM 9457 O  O   . HOH L 4 .   ? -52.819 -7.509  32.425  1   44.25  ? 519 HOH D O   1 
HETATM 9458 O  O   . HOH L 4 .   ? -48.616 -4.077  34.522  1   53.06  ? 520 HOH D O   1 
HETATM 9459 O  O   . HOH L 4 .   ? -37.275 -20.421 49.907  1   45.94  ? 521 HOH D O   1 
HETATM 9460 O  O   . HOH L 4 .   ? -40.799 -1.319  42.348  1   21.72  ? 522 HOH D O   1 
HETATM 9461 O  O   . HOH L 4 .   ? -42.386 -14.651 24.492  1   36.3   ? 523 HOH D O   1 
HETATM 9462 O  O   . HOH L 4 .   ? -53.429 -13.176 21.054  1   19.95  ? 524 HOH D O   1 
HETATM 9463 O  O   . HOH L 4 .   ? -51.432 -11.533 41.364  1   28.19  ? 525 HOH D O   1 
HETATM 9464 O  O   . HOH L 4 .   ? -37.877 -32.377 29.911  1   49.91  ? 526 HOH D O   1 
HETATM 9465 O  O   . HOH L 4 .   ? -49.778 -1.773  17.684  1   44.34  ? 527 HOH D O   1 
HETATM 9466 O  O   . HOH L 4 .   ? -46.036 -4.625  46.088  1   20.87  ? 528 HOH D O   1 
HETATM 9467 O  O   . HOH L 4 .   ? -22.085 -7.912  37.276  1   29.55  ? 529 HOH D O   1 
HETATM 9468 O  O   . HOH L 4 .   ? -49.002 -16.502 17.303  1   24.83  ? 530 HOH D O   1 
HETATM 9469 O  O   . HOH L 4 .   ? -50.778 -16.839 36.776  1   64.13  ? 531 HOH D O   1 
HETATM 9470 O  O   . HOH L 4 .   ? -43.081 -33.958 37.171  1   25.67  ? 532 HOH D O   1 
HETATM 9471 O  O   . HOH L 4 .   ? -48.899 -31.032 21.059  1   18.5   ? 533 HOH D O   1 
HETATM 9472 O  O   . HOH L 4 .   ? -56.285 0.811   19.776  1   22.14  ? 534 HOH D O   1 
HETATM 9473 O  O   . HOH L 4 .   ? -50.353 -10.748 46.065  1   52.41  ? 535 HOH D O   1 
HETATM 9474 O  O   . HOH L 4 .   ? -40.581 -18.541 28.594  1   42.25  ? 536 HOH D O   1 
HETATM 9475 O  O   . HOH L 4 .   ? -38.535 -3.742  27.51   1   32.86  ? 537 HOH D O   1 
HETATM 9476 O  O   . HOH L 4 .   ? -28.55  -23.531 44.879  1   20.89  ? 538 HOH D O   1 
HETATM 9477 O  O   . HOH L 4 .   ? -46.955 -14.592 43.073  1   46.99  ? 539 HOH D O   1 
HETATM 9478 O  O   . HOH L 4 .   ? -23.862 -27.236 24.457  1   48.47  ? 540 HOH D O   1 
HETATM 9479 O  O   . HOH L 4 .   ? -36.621 -20.263 19.446  1   46.86  ? 541 HOH D O   1 
HETATM 9480 O  O   . HOH L 4 .   ? -45.91  -28.282 38.165  1   28.76  ? 542 HOH D O   1 
HETATM 9481 O  O   . HOH L 4 .   ? -54.415 -32.918 46.813  1   15.83  ? 543 HOH D O   1 
HETATM 9482 O  O   . HOH L 4 .   ? -41.266 1.421   45.988  1   47.5   ? 544 HOH D O   1 
HETATM 9483 O  O   . HOH L 4 .   ? -29.950 -5.152  54.537  1   58.46  ? 545 HOH D O   1 
HETATM 9484 O  O   . HOH L 4 .   ? -39.994 -29.853 30.966  1   23.7   ? 546 HOH D O   1 
HETATM 9485 O  O   . HOH L 4 .   ? -50.74  -10.162 38.734  1   21.76  ? 547 HOH D O   1 
HETATM 9486 O  O   . HOH L 4 .   ? -21.99  -25.882 40.194  1   35.79  ? 548 HOH D O   1 
HETATM 9487 O  O   . HOH L 4 .   ? -33.086 -22.02  49.168  1   25.49  ? 549 HOH D O   1 
HETATM 9488 O  O   . HOH L 4 .   ? -35.063 -33.058 32.75   1   14.12  ? 550 HOH D O   1 
HETATM 9489 O  O   . HOH L 4 .   ? -44.251 -6.106  31.088  1   31.61  ? 551 HOH D O   1 
HETATM 9490 O  O   . HOH L 4 .   ? -46.443 -19.975 19.127  1   21.59  ? 552 HOH D O   1 
HETATM 9491 O  O   . HOH L 4 .   ? -43.092 -20.412 27.972  1   55.72  ? 553 HOH D O   1 
HETATM 9492 O  O   . HOH L 4 .   ? -42.264 -22.556 29.696  1   45.15  ? 554 HOH D O   1 
HETATM 9493 O  O   . HOH L 4 .   ? -30.73  -31.297 29.32   1   36.23  ? 555 HOH D O   1 
HETATM 9494 O  O   . HOH L 4 .   ? -42.063 -16.477 29.744  1   43.57  ? 556 HOH D O   1 
HETATM 9495 O  O   . HOH L 4 .   ? -38.967 -32.179 35.324  1   25.72  ? 557 HOH D O   1 
HETATM 9496 O  O   . HOH L 4 .   ? -42.31  3.115   43.929  1   33.73  ? 558 HOH D O   1 
HETATM 9497 O  O   . HOH L 4 .   ? -32.754 -31.304 27.099  1   40.59  ? 559 HOH D O   1 
HETATM 9498 O  O   . HOH L 4 .   ? -44.188 -18.081 29.605  1   29.93  ? 560 HOH D O   1 
# 
