data_9ET1
# 
_entry.id   9ET1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ET1         pdb_00009et1 10.2210/pdb9et1/pdb 
WWPDB D_1292137121 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ET1 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cyclin-dependent kinase 2' 34354.770 2   2.7.11.22 ? ? ? 
2 polymer     man Cyclin-A2                   30817.473 2   ?         ? ? ? 
3 non-polymer syn 4-iodanylbenzamide          247.033   3   ?         ? ? ? 
4 water       nat water                       18.015    284 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cell division protein kinase 2,p33 protein kinase' 
2 Cyclin-A                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
2 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
B,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 4-iodanylbenzamide IJL 
4 water              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   SER n 
1 5   MET n 
1 6   GLU n 
1 7   ASN n 
1 8   PHE n 
1 9   GLN n 
1 10  LYS n 
1 11  VAL n 
1 12  GLU n 
1 13  LYS n 
1 14  ILE n 
1 15  GLY n 
1 16  GLU n 
1 17  GLY n 
1 18  THR n 
1 19  TYR n 
1 20  GLY n 
1 21  VAL n 
1 22  VAL n 
1 23  TYR n 
1 24  LYS n 
1 25  ALA n 
1 26  ARG n 
1 27  ASN n 
1 28  LYS n 
1 29  LEU n 
1 30  THR n 
1 31  GLY n 
1 32  GLU n 
1 33  VAL n 
1 34  VAL n 
1 35  ALA n 
1 36  LEU n 
1 37  LYS n 
1 38  LYS n 
1 39  ILE n 
1 40  ARG n 
1 41  LEU n 
1 42  ASP n 
1 43  THR n 
1 44  GLU n 
1 45  THR n 
1 46  GLU n 
1 47  GLY n 
1 48  VAL n 
1 49  PRO n 
1 50  SER n 
1 51  THR n 
1 52  ALA n 
1 53  ILE n 
1 54  ARG n 
1 55  GLU n 
1 56  ILE n 
1 57  SER n 
1 58  LEU n 
1 59  LEU n 
1 60  LYS n 
1 61  GLU n 
1 62  LEU n 
1 63  ASN n 
1 64  HIS n 
1 65  PRO n 
1 66  ASN n 
1 67  ILE n 
1 68  VAL n 
1 69  LYS n 
1 70  LEU n 
1 71  LEU n 
1 72  ASP n 
1 73  VAL n 
1 74  ILE n 
1 75  HIS n 
1 76  THR n 
1 77  GLU n 
1 78  ASN n 
1 79  LYS n 
1 80  LEU n 
1 81  TYR n 
1 82  LEU n 
1 83  VAL n 
1 84  PHE n 
1 85  GLU n 
1 86  PHE n 
1 87  LEU n 
1 88  HIS n 
1 89  GLN n 
1 90  ASP n 
1 91  LEU n 
1 92  LYS n 
1 93  LYS n 
1 94  PHE n 
1 95  MET n 
1 96  ASP n 
1 97  ALA n 
1 98  SER n 
1 99  ALA n 
1 100 LEU n 
1 101 THR n 
1 102 GLY n 
1 103 ILE n 
1 104 PRO n 
1 105 LEU n 
1 106 PRO n 
1 107 LEU n 
1 108 ILE n 
1 109 LYS n 
1 110 SER n 
1 111 TYR n 
1 112 LEU n 
1 113 PHE n 
1 114 GLN n 
1 115 LEU n 
1 116 LEU n 
1 117 GLN n 
1 118 GLY n 
1 119 LEU n 
1 120 ALA n 
1 121 PHE n 
1 122 CYS n 
1 123 HIS n 
1 124 SER n 
1 125 HIS n 
1 126 ARG n 
1 127 VAL n 
1 128 LEU n 
1 129 HIS n 
1 130 ARG n 
1 131 ASP n 
1 132 LEU n 
1 133 LYS n 
1 134 PRO n 
1 135 GLN n 
1 136 ASN n 
1 137 LEU n 
1 138 LEU n 
1 139 ILE n 
1 140 ASN n 
1 141 THR n 
1 142 GLU n 
1 143 GLY n 
1 144 ALA n 
1 145 ILE n 
1 146 LYS n 
1 147 LEU n 
1 148 ALA n 
1 149 ASP n 
1 150 PHE n 
1 151 GLY n 
1 152 LEU n 
1 153 ALA n 
1 154 ARG n 
1 155 ALA n 
1 156 PHE n 
1 157 GLY n 
1 158 VAL n 
1 159 PRO n 
1 160 VAL n 
1 161 ARG n 
1 162 THR n 
1 163 TYR n 
1 164 TPO n 
1 165 HIS n 
1 166 GLU n 
1 167 VAL n 
1 168 VAL n 
1 169 THR n 
1 170 LEU n 
1 171 TRP n 
1 172 TYR n 
1 173 ARG n 
1 174 ALA n 
1 175 PRO n 
1 176 GLU n 
1 177 ILE n 
1 178 LEU n 
1 179 LEU n 
1 180 GLY n 
1 181 CYS n 
1 182 LYS n 
1 183 TYR n 
1 184 TYR n 
1 185 SER n 
1 186 THR n 
1 187 ALA n 
1 188 VAL n 
1 189 ASP n 
1 190 ILE n 
1 191 TRP n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 CYS n 
1 196 ILE n 
1 197 PHE n 
1 198 ALA n 
1 199 GLU n 
1 200 MET n 
1 201 VAL n 
1 202 THR n 
1 203 ARG n 
1 204 ARG n 
1 205 ALA n 
1 206 LEU n 
1 207 PHE n 
1 208 PRO n 
1 209 GLY n 
1 210 ASP n 
1 211 SER n 
1 212 GLU n 
1 213 ILE n 
1 214 ASP n 
1 215 GLN n 
1 216 LEU n 
1 217 PHE n 
1 218 ARG n 
1 219 ILE n 
1 220 PHE n 
1 221 ARG n 
1 222 THR n 
1 223 LEU n 
1 224 GLY n 
1 225 THR n 
1 226 PRO n 
1 227 ASP n 
1 228 GLU n 
1 229 VAL n 
1 230 VAL n 
1 231 TRP n 
1 232 PRO n 
1 233 GLY n 
1 234 VAL n 
1 235 THR n 
1 236 SER n 
1 237 MET n 
1 238 PRO n 
1 239 ASP n 
1 240 TYR n 
1 241 LYS n 
1 242 PRO n 
1 243 SER n 
1 244 PHE n 
1 245 PRO n 
1 246 LYS n 
1 247 TRP n 
1 248 ALA n 
1 249 ARG n 
1 250 GLN n 
1 251 ASP n 
1 252 PHE n 
1 253 SER n 
1 254 LYS n 
1 255 VAL n 
1 256 VAL n 
1 257 PRO n 
1 258 PRO n 
1 259 LEU n 
1 260 ASP n 
1 261 GLU n 
1 262 ASP n 
1 263 GLY n 
1 264 ARG n 
1 265 SER n 
1 266 LEU n 
1 267 LEU n 
1 268 SER n 
1 269 GLN n 
1 270 MET n 
1 271 LEU n 
1 272 HIS n 
1 273 TYR n 
1 274 ASP n 
1 275 PRO n 
1 276 ASN n 
1 277 LYS n 
1 278 ARG n 
1 279 ILE n 
1 280 SER n 
1 281 ALA n 
1 282 LYS n 
1 283 ALA n 
1 284 ALA n 
1 285 LEU n 
1 286 ALA n 
1 287 HIS n 
1 288 PRO n 
1 289 PHE n 
1 290 PHE n 
1 291 GLN n 
1 292 ASP n 
1 293 VAL n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 VAL n 
1 298 PRO n 
1 299 HIS n 
1 300 LEU n 
1 301 ARG n 
1 302 LEU n 
2 1   GLY n 
2 2   VAL n 
2 3   ASN n 
2 4   GLU n 
2 5   VAL n 
2 6   PRO n 
2 7   ASP n 
2 8   TYR n 
2 9   HIS n 
2 10  GLU n 
2 11  ASP n 
2 12  ILE n 
2 13  HIS n 
2 14  THR n 
2 15  TYR n 
2 16  LEU n 
2 17  ARG n 
2 18  GLU n 
2 19  MET n 
2 20  GLU n 
2 21  VAL n 
2 22  LYS n 
2 23  CYS n 
2 24  LYS n 
2 25  PRO n 
2 26  LYS n 
2 27  VAL n 
2 28  GLY n 
2 29  TYR n 
2 30  MET n 
2 31  LYS n 
2 32  LYS n 
2 33  GLN n 
2 34  PRO n 
2 35  ASP n 
2 36  ILE n 
2 37  THR n 
2 38  ASN n 
2 39  SER n 
2 40  MET n 
2 41  ARG n 
2 42  ALA n 
2 43  ILE n 
2 44  LEU n 
2 45  VAL n 
2 46  ASP n 
2 47  TRP n 
2 48  LEU n 
2 49  VAL n 
2 50  GLU n 
2 51  VAL n 
2 52  GLY n 
2 53  GLU n 
2 54  GLU n 
2 55  TYR n 
2 56  LYS n 
2 57  LEU n 
2 58  GLN n 
2 59  ASN n 
2 60  GLU n 
2 61  THR n 
2 62  LEU n 
2 63  HIS n 
2 64  LEU n 
2 65  ALA n 
2 66  VAL n 
2 67  ASN n 
2 68  TYR n 
2 69  ILE n 
2 70  ASP n 
2 71  ARG n 
2 72  PHE n 
2 73  LEU n 
2 74  SER n 
2 75  SER n 
2 76  MET n 
2 77  SER n 
2 78  VAL n 
2 79  LEU n 
2 80  ARG n 
2 81  GLY n 
2 82  LYS n 
2 83  LEU n 
2 84  GLN n 
2 85  LEU n 
2 86  VAL n 
2 87  GLY n 
2 88  THR n 
2 89  ALA n 
2 90  ALA n 
2 91  MET n 
2 92  LEU n 
2 93  LEU n 
2 94  ALA n 
2 95  SER n 
2 96  LYS n 
2 97  PHE n 
2 98  GLU n 
2 99  GLU n 
2 100 ILE n 
2 101 TYR n 
2 102 PRO n 
2 103 PRO n 
2 104 GLU n 
2 105 VAL n 
2 106 ALA n 
2 107 GLU n 
2 108 PHE n 
2 109 VAL n 
2 110 TYR n 
2 111 ILE n 
2 112 THR n 
2 113 ASP n 
2 114 ASP n 
2 115 THR n 
2 116 TYR n 
2 117 THR n 
2 118 LYS n 
2 119 LYS n 
2 120 GLN n 
2 121 VAL n 
2 122 LEU n 
2 123 ARG n 
2 124 MET n 
2 125 GLU n 
2 126 HIS n 
2 127 LEU n 
2 128 VAL n 
2 129 LEU n 
2 130 LYS n 
2 131 VAL n 
2 132 LEU n 
2 133 ALA n 
2 134 PHE n 
2 135 ASP n 
2 136 LEU n 
2 137 ALA n 
2 138 ALA n 
2 139 PRO n 
2 140 THR n 
2 141 ILE n 
2 142 ASN n 
2 143 GLN n 
2 144 PHE n 
2 145 LEU n 
2 146 THR n 
2 147 GLN n 
2 148 TYR n 
2 149 PHE n 
2 150 LEU n 
2 151 HIS n 
2 152 GLN n 
2 153 GLN n 
2 154 PRO n 
2 155 ALA n 
2 156 ASN n 
2 157 CYS n 
2 158 LYS n 
2 159 VAL n 
2 160 GLU n 
2 161 SER n 
2 162 LEU n 
2 163 ALA n 
2 164 MET n 
2 165 PHE n 
2 166 LEU n 
2 167 GLY n 
2 168 GLU n 
2 169 LEU n 
2 170 SER n 
2 171 LEU n 
2 172 ILE n 
2 173 ASP n 
2 174 ALA n 
2 175 ASP n 
2 176 PRO n 
2 177 TYR n 
2 178 LEU n 
2 179 LYS n 
2 180 TYR n 
2 181 LEU n 
2 182 PRO n 
2 183 SER n 
2 184 VAL n 
2 185 ILE n 
2 186 ALA n 
2 187 ALA n 
2 188 ALA n 
2 189 ALA n 
2 190 PHE n 
2 191 HIS n 
2 192 LEU n 
2 193 ALA n 
2 194 LEU n 
2 195 TYR n 
2 196 THR n 
2 197 VAL n 
2 198 THR n 
2 199 GLY n 
2 200 GLN n 
2 201 SER n 
2 202 TRP n 
2 203 PRO n 
2 204 GLU n 
2 205 SER n 
2 206 LEU n 
2 207 VAL n 
2 208 GLN n 
2 209 LYS n 
2 210 THR n 
2 211 GLY n 
2 212 TYR n 
2 213 THR n 
2 214 LEU n 
2 215 GLU n 
2 216 THR n 
2 217 LEU n 
2 218 LYS n 
2 219 PRO n 
2 220 CYS n 
2 221 LEU n 
2 222 LEU n 
2 223 ASP n 
2 224 LEU n 
2 225 HIS n 
2 226 GLN n 
2 227 THR n 
2 228 TYR n 
2 229 LEU n 
2 230 ARG n 
2 231 ALA n 
2 232 PRO n 
2 233 GLN n 
2 234 HIS n 
2 235 ALA n 
2 236 GLN n 
2 237 GLN n 
2 238 SER n 
2 239 ILE n 
2 240 ARG n 
2 241 GLU n 
2 242 LYS n 
2 243 TYR n 
2 244 LYS n 
2 245 ASN n 
2 246 SER n 
2 247 LYS n 
2 248 TYR n 
2 249 HIS n 
2 250 GLY n 
2 251 VAL n 
2 252 SER n 
2 253 LEU n 
2 254 LEU n 
2 255 ASN n 
2 256 PRO n 
2 257 PRO n 
2 258 GLU n 
2 259 THR n 
2 260 LEU n 
2 261 ASN n 
2 262 VAL n 
2 263 HIS n 
2 264 HIS n 
2 265 HIS n 
2 266 HIS n 
2 267 HIS n 
2 268 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
2 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE            ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE           ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE         ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'    ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE           ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE          ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'    ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE            ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE          ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER              ?                  'H2 O'           18.015  
IJL non-polymer         . 4-iodanylbenzamide ?                  'C7 H6 I N O'    247.033 
ILE 'L-peptide linking' y ISOLEUCINE         ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE            ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE             ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE         ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE      ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE            ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE             ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE          ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE   PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN         ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE           ?                  'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE             ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -3  -3  GLY GLY A . n 
A 1 2   PRO 2   -2  -2  PRO PRO A . n 
A 1 3   GLY 3   -1  -1  GLY GLY A . n 
A 1 4   SER 4   0   0   SER SER A . n 
A 1 5   MET 5   1   1   MET MET A . n 
A 1 6   GLU 6   2   2   GLU GLU A . n 
A 1 7   ASN 7   3   3   ASN ASN A . n 
A 1 8   PHE 8   4   4   PHE PHE A . n 
A 1 9   GLN 9   5   5   GLN GLN A . n 
A 1 10  LYS 10  6   6   LYS LYS A . n 
A 1 11  VAL 11  7   7   VAL VAL A . n 
A 1 12  GLU 12  8   8   GLU GLU A . n 
A 1 13  LYS 13  9   9   LYS LYS A . n 
A 1 14  ILE 14  10  10  ILE ILE A . n 
A 1 15  GLY 15  11  11  GLY GLY A . n 
A 1 16  GLU 16  12  12  GLU GLU A . n 
A 1 17  GLY 17  13  13  GLY GLY A . n 
A 1 18  THR 18  14  14  THR THR A . n 
A 1 19  TYR 19  15  15  TYR TYR A . n 
A 1 20  GLY 20  16  16  GLY GLY A . n 
A 1 21  VAL 21  17  17  VAL VAL A . n 
A 1 22  VAL 22  18  18  VAL VAL A . n 
A 1 23  TYR 23  19  19  TYR TYR A . n 
A 1 24  LYS 24  20  20  LYS LYS A . n 
A 1 25  ALA 25  21  21  ALA ALA A . n 
A 1 26  ARG 26  22  22  ARG ARG A . n 
A 1 27  ASN 27  23  23  ASN ASN A . n 
A 1 28  LYS 28  24  24  LYS LYS A . n 
A 1 29  LEU 29  25  25  LEU LEU A . n 
A 1 30  THR 30  26  26  THR THR A . n 
A 1 31  GLY 31  27  27  GLY GLY A . n 
A 1 32  GLU 32  28  28  GLU GLU A . n 
A 1 33  VAL 33  29  29  VAL VAL A . n 
A 1 34  VAL 34  30  30  VAL VAL A . n 
A 1 35  ALA 35  31  31  ALA ALA A . n 
A 1 36  LEU 36  32  32  LEU LEU A . n 
A 1 37  LYS 37  33  33  LYS LYS A . n 
A 1 38  LYS 38  34  34  LYS LYS A . n 
A 1 39  ILE 39  35  35  ILE ILE A . n 
A 1 40  ARG 40  36  36  ARG ARG A . n 
A 1 41  LEU 41  37  37  LEU LEU A . n 
A 1 42  ASP 42  38  38  ASP ASP A . n 
A 1 43  THR 43  39  39  THR THR A . n 
A 1 44  GLU 44  40  40  GLU GLU A . n 
A 1 45  THR 45  41  41  THR THR A . n 
A 1 46  GLU 46  42  42  GLU GLU A . n 
A 1 47  GLY 47  43  43  GLY GLY A . n 
A 1 48  VAL 48  44  44  VAL VAL A . n 
A 1 49  PRO 49  45  45  PRO PRO A . n 
A 1 50  SER 50  46  46  SER SER A . n 
A 1 51  THR 51  47  47  THR THR A . n 
A 1 52  ALA 52  48  48  ALA ALA A . n 
A 1 53  ILE 53  49  49  ILE ILE A . n 
A 1 54  ARG 54  50  50  ARG ARG A . n 
A 1 55  GLU 55  51  51  GLU GLU A . n 
A 1 56  ILE 56  52  52  ILE ILE A . n 
A 1 57  SER 57  53  53  SER SER A . n 
A 1 58  LEU 58  54  54  LEU LEU A . n 
A 1 59  LEU 59  55  55  LEU LEU A . n 
A 1 60  LYS 60  56  56  LYS LYS A . n 
A 1 61  GLU 61  57  57  GLU GLU A . n 
A 1 62  LEU 62  58  58  LEU LEU A . n 
A 1 63  ASN 63  59  59  ASN ASN A . n 
A 1 64  HIS 64  60  60  HIS HIS A . n 
A 1 65  PRO 65  61  61  PRO PRO A . n 
A 1 66  ASN 66  62  62  ASN ASN A . n 
A 1 67  ILE 67  63  63  ILE ILE A . n 
A 1 68  VAL 68  64  64  VAL VAL A . n 
A 1 69  LYS 69  65  65  LYS LYS A . n 
A 1 70  LEU 70  66  66  LEU LEU A . n 
A 1 71  LEU 71  67  67  LEU LEU A . n 
A 1 72  ASP 72  68  68  ASP ASP A . n 
A 1 73  VAL 73  69  69  VAL VAL A . n 
A 1 74  ILE 74  70  70  ILE ILE A . n 
A 1 75  HIS 75  71  71  HIS HIS A . n 
A 1 76  THR 76  72  72  THR THR A . n 
A 1 77  GLU 77  73  73  GLU GLU A . n 
A 1 78  ASN 78  74  74  ASN ASN A . n 
A 1 79  LYS 79  75  75  LYS LYS A . n 
A 1 80  LEU 80  76  76  LEU LEU A . n 
A 1 81  TYR 81  77  77  TYR TYR A . n 
A 1 82  LEU 82  78  78  LEU LEU A . n 
A 1 83  VAL 83  79  79  VAL VAL A . n 
A 1 84  PHE 84  80  80  PHE PHE A . n 
A 1 85  GLU 85  81  81  GLU GLU A . n 
A 1 86  PHE 86  82  82  PHE PHE A . n 
A 1 87  LEU 87  83  83  LEU LEU A . n 
A 1 88  HIS 88  84  84  HIS HIS A . n 
A 1 89  GLN 89  85  85  GLN GLN A . n 
A 1 90  ASP 90  86  86  ASP ASP A . n 
A 1 91  LEU 91  87  87  LEU LEU A . n 
A 1 92  LYS 92  88  88  LYS LYS A . n 
A 1 93  LYS 93  89  89  LYS LYS A . n 
A 1 94  PHE 94  90  90  PHE PHE A . n 
A 1 95  MET 95  91  91  MET MET A . n 
A 1 96  ASP 96  92  92  ASP ASP A . n 
A 1 97  ALA 97  93  93  ALA ALA A . n 
A 1 98  SER 98  94  94  SER SER A . n 
A 1 99  ALA 99  95  95  ALA ALA A . n 
A 1 100 LEU 100 96  96  LEU LEU A . n 
A 1 101 THR 101 97  97  THR THR A . n 
A 1 102 GLY 102 98  98  GLY GLY A . n 
A 1 103 ILE 103 99  99  ILE ILE A . n 
A 1 104 PRO 104 100 100 PRO PRO A . n 
A 1 105 LEU 105 101 101 LEU LEU A . n 
A 1 106 PRO 106 102 102 PRO PRO A . n 
A 1 107 LEU 107 103 103 LEU LEU A . n 
A 1 108 ILE 108 104 104 ILE ILE A . n 
A 1 109 LYS 109 105 105 LYS LYS A . n 
A 1 110 SER 110 106 106 SER SER A . n 
A 1 111 TYR 111 107 107 TYR TYR A . n 
A 1 112 LEU 112 108 108 LEU LEU A . n 
A 1 113 PHE 113 109 109 PHE PHE A . n 
A 1 114 GLN 114 110 110 GLN GLN A . n 
A 1 115 LEU 115 111 111 LEU LEU A . n 
A 1 116 LEU 116 112 112 LEU LEU A . n 
A 1 117 GLN 117 113 113 GLN GLN A . n 
A 1 118 GLY 118 114 114 GLY GLY A . n 
A 1 119 LEU 119 115 115 LEU LEU A . n 
A 1 120 ALA 120 116 116 ALA ALA A . n 
A 1 121 PHE 121 117 117 PHE PHE A . n 
A 1 122 CYS 122 118 118 CYS CYS A . n 
A 1 123 HIS 123 119 119 HIS HIS A . n 
A 1 124 SER 124 120 120 SER SER A . n 
A 1 125 HIS 125 121 121 HIS HIS A . n 
A 1 126 ARG 126 122 122 ARG ARG A . n 
A 1 127 VAL 127 123 123 VAL VAL A . n 
A 1 128 LEU 128 124 124 LEU LEU A . n 
A 1 129 HIS 129 125 125 HIS HIS A . n 
A 1 130 ARG 130 126 126 ARG ARG A . n 
A 1 131 ASP 131 127 127 ASP ASP A . n 
A 1 132 LEU 132 128 128 LEU LEU A . n 
A 1 133 LYS 133 129 129 LYS LYS A . n 
A 1 134 PRO 134 130 130 PRO PRO A . n 
A 1 135 GLN 135 131 131 GLN GLN A . n 
A 1 136 ASN 136 132 132 ASN ASN A . n 
A 1 137 LEU 137 133 133 LEU LEU A . n 
A 1 138 LEU 138 134 134 LEU LEU A . n 
A 1 139 ILE 139 135 135 ILE ILE A . n 
A 1 140 ASN 140 136 136 ASN ASN A . n 
A 1 141 THR 141 137 137 THR THR A . n 
A 1 142 GLU 142 138 138 GLU GLU A . n 
A 1 143 GLY 143 139 139 GLY GLY A . n 
A 1 144 ALA 144 140 140 ALA ALA A . n 
A 1 145 ILE 145 141 141 ILE ILE A . n 
A 1 146 LYS 146 142 142 LYS LYS A . n 
A 1 147 LEU 147 143 143 LEU LEU A . n 
A 1 148 ALA 148 144 144 ALA ALA A . n 
A 1 149 ASP 149 145 145 ASP ASP A . n 
A 1 150 PHE 150 146 146 PHE PHE A . n 
A 1 151 GLY 151 147 147 GLY GLY A . n 
A 1 152 LEU 152 148 148 LEU LEU A . n 
A 1 153 ALA 153 149 149 ALA ALA A . n 
A 1 154 ARG 154 150 150 ARG ARG A . n 
A 1 155 ALA 155 151 151 ALA ALA A . n 
A 1 156 PHE 156 152 152 PHE PHE A . n 
A 1 157 GLY 157 153 153 GLY GLY A . n 
A 1 158 VAL 158 154 154 VAL VAL A . n 
A 1 159 PRO 159 155 155 PRO PRO A . n 
A 1 160 VAL 160 156 156 VAL VAL A . n 
A 1 161 ARG 161 157 157 ARG ARG A . n 
A 1 162 THR 162 158 158 THR THR A . n 
A 1 163 TYR 163 159 159 TYR TYR A . n 
A 1 164 TPO 164 160 160 TPO TPO A . n 
A 1 165 HIS 165 161 161 HIS HIS A . n 
A 1 166 GLU 166 162 162 GLU GLU A . n 
A 1 167 VAL 167 163 163 VAL VAL A . n 
A 1 168 VAL 168 164 164 VAL VAL A . n 
A 1 169 THR 169 165 165 THR THR A . n 
A 1 170 LEU 170 166 166 LEU LEU A . n 
A 1 171 TRP 171 167 167 TRP TRP A . n 
A 1 172 TYR 172 168 168 TYR TYR A . n 
A 1 173 ARG 173 169 169 ARG ARG A . n 
A 1 174 ALA 174 170 170 ALA ALA A . n 
A 1 175 PRO 175 171 171 PRO PRO A . n 
A 1 176 GLU 176 172 172 GLU GLU A . n 
A 1 177 ILE 177 173 173 ILE ILE A . n 
A 1 178 LEU 178 174 174 LEU LEU A . n 
A 1 179 LEU 179 175 175 LEU LEU A . n 
A 1 180 GLY 180 176 176 GLY GLY A . n 
A 1 181 CYS 181 177 177 CYS CYS A . n 
A 1 182 LYS 182 178 178 LYS LYS A . n 
A 1 183 TYR 183 179 179 TYR TYR A . n 
A 1 184 TYR 184 180 180 TYR TYR A . n 
A 1 185 SER 185 181 181 SER SER A . n 
A 1 186 THR 186 182 182 THR THR A . n 
A 1 187 ALA 187 183 183 ALA ALA A . n 
A 1 188 VAL 188 184 184 VAL VAL A . n 
A 1 189 ASP 189 185 185 ASP ASP A . n 
A 1 190 ILE 190 186 186 ILE ILE A . n 
A 1 191 TRP 191 187 187 TRP TRP A . n 
A 1 192 SER 192 188 188 SER SER A . n 
A 1 193 LEU 193 189 189 LEU LEU A . n 
A 1 194 GLY 194 190 190 GLY GLY A . n 
A 1 195 CYS 195 191 191 CYS CYS A . n 
A 1 196 ILE 196 192 192 ILE ILE A . n 
A 1 197 PHE 197 193 193 PHE PHE A . n 
A 1 198 ALA 198 194 194 ALA ALA A . n 
A 1 199 GLU 199 195 195 GLU GLU A . n 
A 1 200 MET 200 196 196 MET MET A . n 
A 1 201 VAL 201 197 197 VAL VAL A . n 
A 1 202 THR 202 198 198 THR THR A . n 
A 1 203 ARG 203 199 199 ARG ARG A . n 
A 1 204 ARG 204 200 200 ARG ARG A . n 
A 1 205 ALA 205 201 201 ALA ALA A . n 
A 1 206 LEU 206 202 202 LEU LEU A . n 
A 1 207 PHE 207 203 203 PHE PHE A . n 
A 1 208 PRO 208 204 204 PRO PRO A . n 
A 1 209 GLY 209 205 205 GLY GLY A . n 
A 1 210 ASP 210 206 206 ASP ASP A . n 
A 1 211 SER 211 207 207 SER SER A . n 
A 1 212 GLU 212 208 208 GLU GLU A . n 
A 1 213 ILE 213 209 209 ILE ILE A . n 
A 1 214 ASP 214 210 210 ASP ASP A . n 
A 1 215 GLN 215 211 211 GLN GLN A . n 
A 1 216 LEU 216 212 212 LEU LEU A . n 
A 1 217 PHE 217 213 213 PHE PHE A . n 
A 1 218 ARG 218 214 214 ARG ARG A . n 
A 1 219 ILE 219 215 215 ILE ILE A . n 
A 1 220 PHE 220 216 216 PHE PHE A . n 
A 1 221 ARG 221 217 217 ARG ARG A . n 
A 1 222 THR 222 218 218 THR THR A . n 
A 1 223 LEU 223 219 219 LEU LEU A . n 
A 1 224 GLY 224 220 220 GLY GLY A . n 
A 1 225 THR 225 221 221 THR THR A . n 
A 1 226 PRO 226 222 222 PRO PRO A . n 
A 1 227 ASP 227 223 223 ASP ASP A . n 
A 1 228 GLU 228 224 224 GLU GLU A . n 
A 1 229 VAL 229 225 225 VAL VAL A . n 
A 1 230 VAL 230 226 226 VAL VAL A . n 
A 1 231 TRP 231 227 227 TRP TRP A . n 
A 1 232 PRO 232 228 228 PRO PRO A . n 
A 1 233 GLY 233 229 229 GLY GLY A . n 
A 1 234 VAL 234 230 230 VAL VAL A . n 
A 1 235 THR 235 231 231 THR THR A . n 
A 1 236 SER 236 232 232 SER SER A . n 
A 1 237 MET 237 233 233 MET MET A . n 
A 1 238 PRO 238 234 234 PRO PRO A . n 
A 1 239 ASP 239 235 235 ASP ASP A . n 
A 1 240 TYR 240 236 236 TYR TYR A . n 
A 1 241 LYS 241 237 237 LYS LYS A . n 
A 1 242 PRO 242 238 238 PRO PRO A . n 
A 1 243 SER 243 239 239 SER SER A . n 
A 1 244 PHE 244 240 240 PHE PHE A . n 
A 1 245 PRO 245 241 241 PRO PRO A . n 
A 1 246 LYS 246 242 242 LYS LYS A . n 
A 1 247 TRP 247 243 243 TRP TRP A . n 
A 1 248 ALA 248 244 244 ALA ALA A . n 
A 1 249 ARG 249 245 245 ARG ARG A . n 
A 1 250 GLN 250 246 246 GLN GLN A . n 
A 1 251 ASP 251 247 247 ASP ASP A . n 
A 1 252 PHE 252 248 248 PHE PHE A . n 
A 1 253 SER 253 249 249 SER SER A . n 
A 1 254 LYS 254 250 250 LYS LYS A . n 
A 1 255 VAL 255 251 251 VAL VAL A . n 
A 1 256 VAL 256 252 252 VAL VAL A . n 
A 1 257 PRO 257 253 253 PRO PRO A . n 
A 1 258 PRO 258 254 254 PRO PRO A . n 
A 1 259 LEU 259 255 255 LEU LEU A . n 
A 1 260 ASP 260 256 256 ASP ASP A . n 
A 1 261 GLU 261 257 257 GLU GLU A . n 
A 1 262 ASP 262 258 258 ASP ASP A . n 
A 1 263 GLY 263 259 259 GLY GLY A . n 
A 1 264 ARG 264 260 260 ARG ARG A . n 
A 1 265 SER 265 261 261 SER SER A . n 
A 1 266 LEU 266 262 262 LEU LEU A . n 
A 1 267 LEU 267 263 263 LEU LEU A . n 
A 1 268 SER 268 264 264 SER SER A . n 
A 1 269 GLN 269 265 265 GLN GLN A . n 
A 1 270 MET 270 266 266 MET MET A . n 
A 1 271 LEU 271 267 267 LEU LEU A . n 
A 1 272 HIS 272 268 268 HIS HIS A . n 
A 1 273 TYR 273 269 269 TYR TYR A . n 
A 1 274 ASP 274 270 270 ASP ASP A . n 
A 1 275 PRO 275 271 271 PRO PRO A . n 
A 1 276 ASN 276 272 272 ASN ASN A . n 
A 1 277 LYS 277 273 273 LYS LYS A . n 
A 1 278 ARG 278 274 274 ARG ARG A . n 
A 1 279 ILE 279 275 275 ILE ILE A . n 
A 1 280 SER 280 276 276 SER SER A . n 
A 1 281 ALA 281 277 277 ALA ALA A . n 
A 1 282 LYS 282 278 278 LYS LYS A . n 
A 1 283 ALA 283 279 279 ALA ALA A . n 
A 1 284 ALA 284 280 280 ALA ALA A . n 
A 1 285 LEU 285 281 281 LEU LEU A . n 
A 1 286 ALA 286 282 282 ALA ALA A . n 
A 1 287 HIS 287 283 283 HIS HIS A . n 
A 1 288 PRO 288 284 284 PRO PRO A . n 
A 1 289 PHE 289 285 285 PHE PHE A . n 
A 1 290 PHE 290 286 286 PHE PHE A . n 
A 1 291 GLN 291 287 287 GLN GLN A . n 
A 1 292 ASP 292 288 288 ASP ASP A . n 
A 1 293 VAL 293 289 289 VAL VAL A . n 
A 1 294 THR 294 290 290 THR THR A . n 
A 1 295 LYS 295 291 291 LYS LYS A . n 
A 1 296 PRO 296 292 292 PRO PRO A . n 
A 1 297 VAL 297 293 293 VAL VAL A . n 
A 1 298 PRO 298 294 294 PRO PRO A . n 
A 1 299 HIS 299 295 295 HIS HIS A . n 
A 1 300 LEU 300 296 296 LEU LEU A . n 
A 1 301 ARG 301 297 297 ARG ARG A . n 
A 1 302 LEU 302 298 298 LEU LEU A . n 
B 2 1   GLY 1   171 171 GLY GLY B . n 
B 2 2   VAL 2   172 172 VAL VAL B . n 
B 2 3   ASN 3   173 173 ASN ASN B . n 
B 2 4   GLU 4   174 174 GLU GLU B . n 
B 2 5   VAL 5   175 175 VAL VAL B . n 
B 2 6   PRO 6   176 176 PRO PRO B . n 
B 2 7   ASP 7   177 177 ASP ASP B . n 
B 2 8   TYR 8   178 178 TYR TYR B . n 
B 2 9   HIS 9   179 179 HIS HIS B . n 
B 2 10  GLU 10  180 180 GLU GLU B . n 
B 2 11  ASP 11  181 181 ASP ASP B . n 
B 2 12  ILE 12  182 182 ILE ILE B . n 
B 2 13  HIS 13  183 183 HIS HIS B . n 
B 2 14  THR 14  184 184 THR THR B . n 
B 2 15  TYR 15  185 185 TYR TYR B . n 
B 2 16  LEU 16  186 186 LEU LEU B . n 
B 2 17  ARG 17  187 187 ARG ARG B . n 
B 2 18  GLU 18  188 188 GLU GLU B . n 
B 2 19  MET 19  189 189 MET MET B . n 
B 2 20  GLU 20  190 190 GLU GLU B . n 
B 2 21  VAL 21  191 191 VAL VAL B . n 
B 2 22  LYS 22  192 192 LYS LYS B . n 
B 2 23  CYS 23  193 193 CYS CYS B . n 
B 2 24  LYS 24  194 194 LYS LYS B . n 
B 2 25  PRO 25  195 195 PRO PRO B . n 
B 2 26  LYS 26  196 196 LYS LYS B . n 
B 2 27  VAL 27  197 197 VAL VAL B . n 
B 2 28  GLY 28  198 198 GLY GLY B . n 
B 2 29  TYR 29  199 199 TYR TYR B . n 
B 2 30  MET 30  200 200 MET MET B . n 
B 2 31  LYS 31  201 201 LYS LYS B . n 
B 2 32  LYS 32  202 202 LYS LYS B . n 
B 2 33  GLN 33  203 203 GLN GLN B . n 
B 2 34  PRO 34  204 204 PRO PRO B . n 
B 2 35  ASP 35  205 205 ASP ASP B . n 
B 2 36  ILE 36  206 206 ILE ILE B . n 
B 2 37  THR 37  207 207 THR THR B . n 
B 2 38  ASN 38  208 208 ASN ASN B . n 
B 2 39  SER 39  209 209 SER SER B . n 
B 2 40  MET 40  210 210 MET MET B . n 
B 2 41  ARG 41  211 211 ARG ARG B . n 
B 2 42  ALA 42  212 212 ALA ALA B . n 
B 2 43  ILE 43  213 213 ILE ILE B . n 
B 2 44  LEU 44  214 214 LEU LEU B . n 
B 2 45  VAL 45  215 215 VAL VAL B . n 
B 2 46  ASP 46  216 216 ASP ASP B . n 
B 2 47  TRP 47  217 217 TRP TRP B . n 
B 2 48  LEU 48  218 218 LEU LEU B . n 
B 2 49  VAL 49  219 219 VAL VAL B . n 
B 2 50  GLU 50  220 220 GLU GLU B . n 
B 2 51  VAL 51  221 221 VAL VAL B . n 
B 2 52  GLY 52  222 222 GLY GLY B . n 
B 2 53  GLU 53  223 223 GLU GLU B . n 
B 2 54  GLU 54  224 224 GLU GLU B . n 
B 2 55  TYR 55  225 225 TYR TYR B . n 
B 2 56  LYS 56  226 226 LYS LYS B . n 
B 2 57  LEU 57  227 227 LEU LEU B . n 
B 2 58  GLN 58  228 228 GLN GLN B . n 
B 2 59  ASN 59  229 229 ASN ASN B . n 
B 2 60  GLU 60  230 230 GLU GLU B . n 
B 2 61  THR 61  231 231 THR THR B . n 
B 2 62  LEU 62  232 232 LEU LEU B . n 
B 2 63  HIS 63  233 233 HIS HIS B . n 
B 2 64  LEU 64  234 234 LEU LEU B . n 
B 2 65  ALA 65  235 235 ALA ALA B . n 
B 2 66  VAL 66  236 236 VAL VAL B . n 
B 2 67  ASN 67  237 237 ASN ASN B . n 
B 2 68  TYR 68  238 238 TYR TYR B . n 
B 2 69  ILE 69  239 239 ILE ILE B . n 
B 2 70  ASP 70  240 240 ASP ASP B . n 
B 2 71  ARG 71  241 241 ARG ARG B . n 
B 2 72  PHE 72  242 242 PHE PHE B . n 
B 2 73  LEU 73  243 243 LEU LEU B . n 
B 2 74  SER 74  244 244 SER SER B . n 
B 2 75  SER 75  245 245 SER SER B . n 
B 2 76  MET 76  246 246 MET MET B . n 
B 2 77  SER 77  247 247 SER SER B . n 
B 2 78  VAL 78  248 248 VAL VAL B . n 
B 2 79  LEU 79  249 249 LEU LEU B . n 
B 2 80  ARG 80  250 250 ARG ARG B . n 
B 2 81  GLY 81  251 251 GLY GLY B . n 
B 2 82  LYS 82  252 252 LYS LYS B . n 
B 2 83  LEU 83  253 253 LEU LEU B . n 
B 2 84  GLN 84  254 254 GLN GLN B . n 
B 2 85  LEU 85  255 255 LEU LEU B . n 
B 2 86  VAL 86  256 256 VAL VAL B . n 
B 2 87  GLY 87  257 257 GLY GLY B . n 
B 2 88  THR 88  258 258 THR THR B . n 
B 2 89  ALA 89  259 259 ALA ALA B . n 
B 2 90  ALA 90  260 260 ALA ALA B . n 
B 2 91  MET 91  261 261 MET MET B . n 
B 2 92  LEU 92  262 262 LEU LEU B . n 
B 2 93  LEU 93  263 263 LEU LEU B . n 
B 2 94  ALA 94  264 264 ALA ALA B . n 
B 2 95  SER 95  265 265 SER SER B . n 
B 2 96  LYS 96  266 266 LYS LYS B . n 
B 2 97  PHE 97  267 267 PHE PHE B . n 
B 2 98  GLU 98  268 268 GLU GLU B . n 
B 2 99  GLU 99  269 269 GLU GLU B . n 
B 2 100 ILE 100 270 270 ILE ILE B . n 
B 2 101 TYR 101 271 271 TYR TYR B . n 
B 2 102 PRO 102 272 272 PRO PRO B . n 
B 2 103 PRO 103 273 273 PRO PRO B . n 
B 2 104 GLU 104 274 274 GLU GLU B . n 
B 2 105 VAL 105 275 275 VAL VAL B . n 
B 2 106 ALA 106 276 276 ALA ALA B . n 
B 2 107 GLU 107 277 277 GLU GLU B . n 
B 2 108 PHE 108 278 278 PHE PHE B . n 
B 2 109 VAL 109 279 279 VAL VAL B . n 
B 2 110 TYR 110 280 280 TYR TYR B . n 
B 2 111 ILE 111 281 281 ILE ILE B . n 
B 2 112 THR 112 282 282 THR THR B . n 
B 2 113 ASP 113 283 283 ASP ASP B . n 
B 2 114 ASP 114 284 284 ASP ASP B . n 
B 2 115 THR 115 285 285 THR THR B . n 
B 2 116 TYR 116 286 286 TYR TYR B . n 
B 2 117 THR 117 287 287 THR THR B . n 
B 2 118 LYS 118 288 288 LYS LYS B . n 
B 2 119 LYS 119 289 289 LYS LYS B . n 
B 2 120 GLN 120 290 290 GLN GLN B . n 
B 2 121 VAL 121 291 291 VAL VAL B . n 
B 2 122 LEU 122 292 292 LEU LEU B . n 
B 2 123 ARG 123 293 293 ARG ARG B . n 
B 2 124 MET 124 294 294 MET MET B . n 
B 2 125 GLU 125 295 295 GLU GLU B . n 
B 2 126 HIS 126 296 296 HIS HIS B . n 
B 2 127 LEU 127 297 297 LEU LEU B . n 
B 2 128 VAL 128 298 298 VAL VAL B . n 
B 2 129 LEU 129 299 299 LEU LEU B . n 
B 2 130 LYS 130 300 300 LYS LYS B . n 
B 2 131 VAL 131 301 301 VAL VAL B . n 
B 2 132 LEU 132 302 302 LEU LEU B . n 
B 2 133 ALA 133 303 303 ALA ALA B . n 
B 2 134 PHE 134 304 304 PHE PHE B . n 
B 2 135 ASP 135 305 305 ASP ASP B . n 
B 2 136 LEU 136 306 306 LEU LEU B . n 
B 2 137 ALA 137 307 307 ALA ALA B . n 
B 2 138 ALA 138 308 308 ALA ALA B . n 
B 2 139 PRO 139 309 309 PRO PRO B . n 
B 2 140 THR 140 310 310 THR THR B . n 
B 2 141 ILE 141 311 311 ILE ILE B . n 
B 2 142 ASN 142 312 312 ASN ASN B . n 
B 2 143 GLN 143 313 313 GLN GLN B . n 
B 2 144 PHE 144 314 314 PHE PHE B . n 
B 2 145 LEU 145 315 315 LEU LEU B . n 
B 2 146 THR 146 316 316 THR THR B . n 
B 2 147 GLN 147 317 317 GLN GLN B . n 
B 2 148 TYR 148 318 318 TYR TYR B . n 
B 2 149 PHE 149 319 319 PHE PHE B . n 
B 2 150 LEU 150 320 320 LEU LEU B . n 
B 2 151 HIS 151 321 321 HIS HIS B . n 
B 2 152 GLN 152 322 322 GLN GLN B . n 
B 2 153 GLN 153 323 323 GLN GLN B . n 
B 2 154 PRO 154 324 324 PRO PRO B . n 
B 2 155 ALA 155 325 325 ALA ALA B . n 
B 2 156 ASN 156 326 326 ASN ASN B . n 
B 2 157 CYS 157 327 327 CYS CYS B . n 
B 2 158 LYS 158 328 328 LYS LYS B . n 
B 2 159 VAL 159 329 329 VAL VAL B . n 
B 2 160 GLU 160 330 330 GLU GLU B . n 
B 2 161 SER 161 331 331 SER SER B . n 
B 2 162 LEU 162 332 332 LEU LEU B . n 
B 2 163 ALA 163 333 333 ALA ALA B . n 
B 2 164 MET 164 334 334 MET MET B . n 
B 2 165 PHE 165 335 335 PHE PHE B . n 
B 2 166 LEU 166 336 336 LEU LEU B . n 
B 2 167 GLY 167 337 337 GLY GLY B . n 
B 2 168 GLU 168 338 338 GLU GLU B . n 
B 2 169 LEU 169 339 339 LEU LEU B . n 
B 2 170 SER 170 340 340 SER SER B . n 
B 2 171 LEU 171 341 341 LEU LEU B . n 
B 2 172 ILE 172 342 342 ILE ILE B . n 
B 2 173 ASP 173 343 343 ASP ASP B . n 
B 2 174 ALA 174 344 344 ALA ALA B . n 
B 2 175 ASP 175 345 345 ASP ASP B . n 
B 2 176 PRO 176 346 346 PRO PRO B . n 
B 2 177 TYR 177 347 347 TYR TYR B . n 
B 2 178 LEU 178 348 348 LEU LEU B . n 
B 2 179 LYS 179 349 349 LYS LYS B . n 
B 2 180 TYR 180 350 350 TYR TYR B . n 
B 2 181 LEU 181 351 351 LEU LEU B . n 
B 2 182 PRO 182 352 352 PRO PRO B . n 
B 2 183 SER 183 353 353 SER SER B . n 
B 2 184 VAL 184 354 354 VAL VAL B . n 
B 2 185 ILE 185 355 355 ILE ILE B . n 
B 2 186 ALA 186 356 356 ALA ALA B . n 
B 2 187 ALA 187 357 357 ALA ALA B . n 
B 2 188 ALA 188 358 358 ALA ALA B . n 
B 2 189 ALA 189 359 359 ALA ALA B . n 
B 2 190 PHE 190 360 360 PHE PHE B . n 
B 2 191 HIS 191 361 361 HIS HIS B . n 
B 2 192 LEU 192 362 362 LEU LEU B . n 
B 2 193 ALA 193 363 363 ALA ALA B . n 
B 2 194 LEU 194 364 364 LEU LEU B . n 
B 2 195 TYR 195 365 365 TYR TYR B . n 
B 2 196 THR 196 366 366 THR THR B . n 
B 2 197 VAL 197 367 367 VAL VAL B . n 
B 2 198 THR 198 368 368 THR THR B . n 
B 2 199 GLY 199 369 369 GLY GLY B . n 
B 2 200 GLN 200 370 370 GLN GLN B . n 
B 2 201 SER 201 371 371 SER SER B . n 
B 2 202 TRP 202 372 372 TRP TRP B . n 
B 2 203 PRO 203 373 373 PRO PRO B . n 
B 2 204 GLU 204 374 374 GLU GLU B . n 
B 2 205 SER 205 375 375 SER SER B . n 
B 2 206 LEU 206 376 376 LEU LEU B . n 
B 2 207 VAL 207 377 377 VAL VAL B . n 
B 2 208 GLN 208 378 378 GLN GLN B . n 
B 2 209 LYS 209 379 379 LYS LYS B . n 
B 2 210 THR 210 380 380 THR THR B . n 
B 2 211 GLY 211 381 381 GLY GLY B . n 
B 2 212 TYR 212 382 382 TYR TYR B . n 
B 2 213 THR 213 383 383 THR THR B . n 
B 2 214 LEU 214 384 384 LEU LEU B . n 
B 2 215 GLU 215 385 385 GLU GLU B . n 
B 2 216 THR 216 386 386 THR THR B . n 
B 2 217 LEU 217 387 387 LEU LEU B . n 
B 2 218 LYS 218 388 388 LYS LYS B . n 
B 2 219 PRO 219 389 389 PRO PRO B . n 
B 2 220 CYS 220 390 390 CYS CYS B . n 
B 2 221 LEU 221 391 391 LEU LEU B . n 
B 2 222 LEU 222 392 392 LEU LEU B . n 
B 2 223 ASP 223 393 393 ASP ASP B . n 
B 2 224 LEU 224 394 394 LEU LEU B . n 
B 2 225 HIS 225 395 395 HIS HIS B . n 
B 2 226 GLN 226 396 396 GLN GLN B . n 
B 2 227 THR 227 397 397 THR THR B . n 
B 2 228 TYR 228 398 398 TYR TYR B . n 
B 2 229 LEU 229 399 399 LEU LEU B . n 
B 2 230 ARG 230 400 400 ARG ARG B . n 
B 2 231 ALA 231 401 401 ALA ALA B . n 
B 2 232 PRO 232 402 402 PRO PRO B . n 
B 2 233 GLN 233 403 403 GLN GLN B . n 
B 2 234 HIS 234 404 404 HIS HIS B . n 
B 2 235 ALA 235 405 405 ALA ALA B . n 
B 2 236 GLN 236 406 406 GLN GLN B . n 
B 2 237 GLN 237 407 407 GLN GLN B . n 
B 2 238 SER 238 408 408 SER SER B . n 
B 2 239 ILE 239 409 409 ILE ILE B . n 
B 2 240 ARG 240 410 410 ARG ARG B . n 
B 2 241 GLU 241 411 411 GLU GLU B . n 
B 2 242 LYS 242 412 412 LYS LYS B . n 
B 2 243 TYR 243 413 413 TYR TYR B . n 
B 2 244 LYS 244 414 414 LYS LYS B . n 
B 2 245 ASN 245 415 415 ASN ASN B . n 
B 2 246 SER 246 416 416 SER SER B . n 
B 2 247 LYS 247 417 417 LYS LYS B . n 
B 2 248 TYR 248 418 418 TYR TYR B . n 
B 2 249 HIS 249 419 419 HIS HIS B . n 
B 2 250 GLY 250 420 420 GLY GLY B . n 
B 2 251 VAL 251 421 421 VAL VAL B . n 
B 2 252 SER 252 422 422 SER SER B . n 
B 2 253 LEU 253 423 423 LEU LEU B . n 
B 2 254 LEU 254 424 424 LEU LEU B . n 
B 2 255 ASN 255 425 425 ASN ASN B . n 
B 2 256 PRO 256 426 426 PRO PRO B . n 
B 2 257 PRO 257 427 427 PRO PRO B . n 
B 2 258 GLU 258 428 428 GLU GLU B . n 
B 2 259 THR 259 429 429 THR THR B . n 
B 2 260 LEU 260 430 430 LEU LEU B . n 
B 2 261 ASN 261 431 431 ASN ASN B . n 
B 2 262 VAL 262 432 432 VAL VAL B . n 
B 2 263 HIS 263 433 ?   ?   ?   B . n 
B 2 264 HIS 264 434 ?   ?   ?   B . n 
B 2 265 HIS 265 435 ?   ?   ?   B . n 
B 2 266 HIS 266 436 ?   ?   ?   B . n 
B 2 267 HIS 267 437 ?   ?   ?   B . n 
B 2 268 HIS 268 438 ?   ?   ?   B . n 
C 1 1   GLY 1   -3  ?   ?   ?   C . n 
C 1 2   PRO 2   -2  ?   ?   ?   C . n 
C 1 3   GLY 3   -1  ?   ?   ?   C . n 
C 1 4   SER 4   0   0   SER SER C . n 
C 1 5   MET 5   1   1   MET MET C . n 
C 1 6   GLU 6   2   2   GLU GLU C . n 
C 1 7   ASN 7   3   3   ASN ASN C . n 
C 1 8   PHE 8   4   4   PHE PHE C . n 
C 1 9   GLN 9   5   5   GLN GLN C . n 
C 1 10  LYS 10  6   6   LYS LYS C . n 
C 1 11  VAL 11  7   7   VAL VAL C . n 
C 1 12  GLU 12  8   8   GLU GLU C . n 
C 1 13  LYS 13  9   9   LYS LYS C . n 
C 1 14  ILE 14  10  10  ILE ILE C . n 
C 1 15  GLY 15  11  11  GLY GLY C . n 
C 1 16  GLU 16  12  12  GLU GLU C . n 
C 1 17  GLY 17  13  13  GLY GLY C . n 
C 1 18  THR 18  14  14  THR THR C . n 
C 1 19  TYR 19  15  15  TYR TYR C . n 
C 1 20  GLY 20  16  16  GLY GLY C . n 
C 1 21  VAL 21  17  17  VAL VAL C . n 
C 1 22  VAL 22  18  18  VAL VAL C . n 
C 1 23  TYR 23  19  19  TYR TYR C . n 
C 1 24  LYS 24  20  20  LYS LYS C . n 
C 1 25  ALA 25  21  21  ALA ALA C . n 
C 1 26  ARG 26  22  22  ARG ARG C . n 
C 1 27  ASN 27  23  23  ASN ASN C . n 
C 1 28  LYS 28  24  24  LYS LYS C . n 
C 1 29  LEU 29  25  25  LEU LEU C . n 
C 1 30  THR 30  26  26  THR THR C . n 
C 1 31  GLY 31  27  27  GLY GLY C . n 
C 1 32  GLU 32  28  28  GLU GLU C . n 
C 1 33  VAL 33  29  29  VAL VAL C . n 
C 1 34  VAL 34  30  30  VAL VAL C . n 
C 1 35  ALA 35  31  31  ALA ALA C . n 
C 1 36  LEU 36  32  32  LEU LEU C . n 
C 1 37  LYS 37  33  33  LYS LYS C . n 
C 1 38  LYS 38  34  34  LYS LYS C . n 
C 1 39  ILE 39  35  35  ILE ILE C . n 
C 1 40  ARG 40  36  36  ARG ARG C . n 
C 1 41  LEU 41  37  37  LEU LEU C . n 
C 1 42  ASP 42  38  38  ASP ASP C . n 
C 1 43  THR 43  39  39  THR THR C . n 
C 1 44  GLU 44  40  40  GLU GLU C . n 
C 1 45  THR 45  41  41  THR THR C . n 
C 1 46  GLU 46  42  42  GLU GLU C . n 
C 1 47  GLY 47  43  43  GLY GLY C . n 
C 1 48  VAL 48  44  44  VAL VAL C . n 
C 1 49  PRO 49  45  45  PRO PRO C . n 
C 1 50  SER 50  46  46  SER SER C . n 
C 1 51  THR 51  47  47  THR THR C . n 
C 1 52  ALA 52  48  48  ALA ALA C . n 
C 1 53  ILE 53  49  49  ILE ILE C . n 
C 1 54  ARG 54  50  50  ARG ARG C . n 
C 1 55  GLU 55  51  51  GLU GLU C . n 
C 1 56  ILE 56  52  52  ILE ILE C . n 
C 1 57  SER 57  53  53  SER SER C . n 
C 1 58  LEU 58  54  54  LEU LEU C . n 
C 1 59  LEU 59  55  55  LEU LEU C . n 
C 1 60  LYS 60  56  56  LYS LYS C . n 
C 1 61  GLU 61  57  57  GLU GLU C . n 
C 1 62  LEU 62  58  58  LEU LEU C . n 
C 1 63  ASN 63  59  59  ASN ASN C . n 
C 1 64  HIS 64  60  60  HIS HIS C . n 
C 1 65  PRO 65  61  61  PRO PRO C . n 
C 1 66  ASN 66  62  62  ASN ASN C . n 
C 1 67  ILE 67  63  63  ILE ILE C . n 
C 1 68  VAL 68  64  64  VAL VAL C . n 
C 1 69  LYS 69  65  65  LYS LYS C . n 
C 1 70  LEU 70  66  66  LEU LEU C . n 
C 1 71  LEU 71  67  67  LEU LEU C . n 
C 1 72  ASP 72  68  68  ASP ASP C . n 
C 1 73  VAL 73  69  69  VAL VAL C . n 
C 1 74  ILE 74  70  70  ILE ILE C . n 
C 1 75  HIS 75  71  71  HIS HIS C . n 
C 1 76  THR 76  72  72  THR THR C . n 
C 1 77  GLU 77  73  73  GLU GLU C . n 
C 1 78  ASN 78  74  74  ASN ASN C . n 
C 1 79  LYS 79  75  75  LYS LYS C . n 
C 1 80  LEU 80  76  76  LEU LEU C . n 
C 1 81  TYR 81  77  77  TYR TYR C . n 
C 1 82  LEU 82  78  78  LEU LEU C . n 
C 1 83  VAL 83  79  79  VAL VAL C . n 
C 1 84  PHE 84  80  80  PHE PHE C . n 
C 1 85  GLU 85  81  81  GLU GLU C . n 
C 1 86  PHE 86  82  82  PHE PHE C . n 
C 1 87  LEU 87  83  83  LEU LEU C . n 
C 1 88  HIS 88  84  84  HIS HIS C . n 
C 1 89  GLN 89  85  85  GLN GLN C . n 
C 1 90  ASP 90  86  86  ASP ASP C . n 
C 1 91  LEU 91  87  87  LEU LEU C . n 
C 1 92  LYS 92  88  88  LYS LYS C . n 
C 1 93  LYS 93  89  89  LYS LYS C . n 
C 1 94  PHE 94  90  90  PHE PHE C . n 
C 1 95  MET 95  91  91  MET MET C . n 
C 1 96  ASP 96  92  92  ASP ASP C . n 
C 1 97  ALA 97  93  93  ALA ALA C . n 
C 1 98  SER 98  94  94  SER SER C . n 
C 1 99  ALA 99  95  95  ALA ALA C . n 
C 1 100 LEU 100 96  96  LEU LEU C . n 
C 1 101 THR 101 97  97  THR THR C . n 
C 1 102 GLY 102 98  98  GLY GLY C . n 
C 1 103 ILE 103 99  99  ILE ILE C . n 
C 1 104 PRO 104 100 100 PRO PRO C . n 
C 1 105 LEU 105 101 101 LEU LEU C . n 
C 1 106 PRO 106 102 102 PRO PRO C . n 
C 1 107 LEU 107 103 103 LEU LEU C . n 
C 1 108 ILE 108 104 104 ILE ILE C . n 
C 1 109 LYS 109 105 105 LYS LYS C . n 
C 1 110 SER 110 106 106 SER SER C . n 
C 1 111 TYR 111 107 107 TYR TYR C . n 
C 1 112 LEU 112 108 108 LEU LEU C . n 
C 1 113 PHE 113 109 109 PHE PHE C . n 
C 1 114 GLN 114 110 110 GLN GLN C . n 
C 1 115 LEU 115 111 111 LEU LEU C . n 
C 1 116 LEU 116 112 112 LEU LEU C . n 
C 1 117 GLN 117 113 113 GLN GLN C . n 
C 1 118 GLY 118 114 114 GLY GLY C . n 
C 1 119 LEU 119 115 115 LEU LEU C . n 
C 1 120 ALA 120 116 116 ALA ALA C . n 
C 1 121 PHE 121 117 117 PHE PHE C . n 
C 1 122 CYS 122 118 118 CYS CYS C . n 
C 1 123 HIS 123 119 119 HIS HIS C . n 
C 1 124 SER 124 120 120 SER SER C . n 
C 1 125 HIS 125 121 121 HIS HIS C . n 
C 1 126 ARG 126 122 122 ARG ARG C . n 
C 1 127 VAL 127 123 123 VAL VAL C . n 
C 1 128 LEU 128 124 124 LEU LEU C . n 
C 1 129 HIS 129 125 125 HIS HIS C . n 
C 1 130 ARG 130 126 126 ARG ARG C . n 
C 1 131 ASP 131 127 127 ASP ASP C . n 
C 1 132 LEU 132 128 128 LEU LEU C . n 
C 1 133 LYS 133 129 129 LYS LYS C . n 
C 1 134 PRO 134 130 130 PRO PRO C . n 
C 1 135 GLN 135 131 131 GLN GLN C . n 
C 1 136 ASN 136 132 132 ASN ASN C . n 
C 1 137 LEU 137 133 133 LEU LEU C . n 
C 1 138 LEU 138 134 134 LEU LEU C . n 
C 1 139 ILE 139 135 135 ILE ILE C . n 
C 1 140 ASN 140 136 136 ASN ASN C . n 
C 1 141 THR 141 137 137 THR THR C . n 
C 1 142 GLU 142 138 138 GLU GLU C . n 
C 1 143 GLY 143 139 139 GLY GLY C . n 
C 1 144 ALA 144 140 140 ALA ALA C . n 
C 1 145 ILE 145 141 141 ILE ILE C . n 
C 1 146 LYS 146 142 142 LYS LYS C . n 
C 1 147 LEU 147 143 143 LEU LEU C . n 
C 1 148 ALA 148 144 144 ALA ALA C . n 
C 1 149 ASP 149 145 145 ASP ASP C . n 
C 1 150 PHE 150 146 146 PHE PHE C . n 
C 1 151 GLY 151 147 147 GLY GLY C . n 
C 1 152 LEU 152 148 148 LEU LEU C . n 
C 1 153 ALA 153 149 149 ALA ALA C . n 
C 1 154 ARG 154 150 150 ARG ARG C . n 
C 1 155 ALA 155 151 151 ALA ALA C . n 
C 1 156 PHE 156 152 152 PHE PHE C . n 
C 1 157 GLY 157 153 153 GLY GLY C . n 
C 1 158 VAL 158 154 154 VAL VAL C . n 
C 1 159 PRO 159 155 155 PRO PRO C . n 
C 1 160 VAL 160 156 156 VAL VAL C . n 
C 1 161 ARG 161 157 157 ARG ARG C . n 
C 1 162 THR 162 158 158 THR THR C . n 
C 1 163 TYR 163 159 159 TYR TYR C . n 
C 1 164 TPO 164 160 160 TPO TPO C . n 
C 1 165 HIS 165 161 161 HIS HIS C . n 
C 1 166 GLU 166 162 162 GLU GLU C . n 
C 1 167 VAL 167 163 163 VAL VAL C . n 
C 1 168 VAL 168 164 164 VAL VAL C . n 
C 1 169 THR 169 165 165 THR THR C . n 
C 1 170 LEU 170 166 166 LEU LEU C . n 
C 1 171 TRP 171 167 167 TRP TRP C . n 
C 1 172 TYR 172 168 168 TYR TYR C . n 
C 1 173 ARG 173 169 169 ARG ARG C . n 
C 1 174 ALA 174 170 170 ALA ALA C . n 
C 1 175 PRO 175 171 171 PRO PRO C . n 
C 1 176 GLU 176 172 172 GLU GLU C . n 
C 1 177 ILE 177 173 173 ILE ILE C . n 
C 1 178 LEU 178 174 174 LEU LEU C . n 
C 1 179 LEU 179 175 175 LEU LEU C . n 
C 1 180 GLY 180 176 176 GLY GLY C . n 
C 1 181 CYS 181 177 177 CYS CYS C . n 
C 1 182 LYS 182 178 178 LYS LYS C . n 
C 1 183 TYR 183 179 179 TYR TYR C . n 
C 1 184 TYR 184 180 180 TYR TYR C . n 
C 1 185 SER 185 181 181 SER SER C . n 
C 1 186 THR 186 182 182 THR THR C . n 
C 1 187 ALA 187 183 183 ALA ALA C . n 
C 1 188 VAL 188 184 184 VAL VAL C . n 
C 1 189 ASP 189 185 185 ASP ASP C . n 
C 1 190 ILE 190 186 186 ILE ILE C . n 
C 1 191 TRP 191 187 187 TRP TRP C . n 
C 1 192 SER 192 188 188 SER SER C . n 
C 1 193 LEU 193 189 189 LEU LEU C . n 
C 1 194 GLY 194 190 190 GLY GLY C . n 
C 1 195 CYS 195 191 191 CYS CYS C . n 
C 1 196 ILE 196 192 192 ILE ILE C . n 
C 1 197 PHE 197 193 193 PHE PHE C . n 
C 1 198 ALA 198 194 194 ALA ALA C . n 
C 1 199 GLU 199 195 195 GLU GLU C . n 
C 1 200 MET 200 196 196 MET MET C . n 
C 1 201 VAL 201 197 197 VAL VAL C . n 
C 1 202 THR 202 198 198 THR THR C . n 
C 1 203 ARG 203 199 199 ARG ARG C . n 
C 1 204 ARG 204 200 200 ARG ARG C . n 
C 1 205 ALA 205 201 201 ALA ALA C . n 
C 1 206 LEU 206 202 202 LEU LEU C . n 
C 1 207 PHE 207 203 203 PHE PHE C . n 
C 1 208 PRO 208 204 204 PRO PRO C . n 
C 1 209 GLY 209 205 205 GLY GLY C . n 
C 1 210 ASP 210 206 206 ASP ASP C . n 
C 1 211 SER 211 207 207 SER SER C . n 
C 1 212 GLU 212 208 208 GLU GLU C . n 
C 1 213 ILE 213 209 209 ILE ILE C . n 
C 1 214 ASP 214 210 210 ASP ASP C . n 
C 1 215 GLN 215 211 211 GLN GLN C . n 
C 1 216 LEU 216 212 212 LEU LEU C . n 
C 1 217 PHE 217 213 213 PHE PHE C . n 
C 1 218 ARG 218 214 214 ARG ARG C . n 
C 1 219 ILE 219 215 215 ILE ILE C . n 
C 1 220 PHE 220 216 216 PHE PHE C . n 
C 1 221 ARG 221 217 217 ARG ARG C . n 
C 1 222 THR 222 218 218 THR THR C . n 
C 1 223 LEU 223 219 219 LEU LEU C . n 
C 1 224 GLY 224 220 220 GLY GLY C . n 
C 1 225 THR 225 221 221 THR THR C . n 
C 1 226 PRO 226 222 222 PRO PRO C . n 
C 1 227 ASP 227 223 223 ASP ASP C . n 
C 1 228 GLU 228 224 224 GLU GLU C . n 
C 1 229 VAL 229 225 225 VAL VAL C . n 
C 1 230 VAL 230 226 226 VAL VAL C . n 
C 1 231 TRP 231 227 227 TRP TRP C . n 
C 1 232 PRO 232 228 228 PRO PRO C . n 
C 1 233 GLY 233 229 229 GLY GLY C . n 
C 1 234 VAL 234 230 230 VAL VAL C . n 
C 1 235 THR 235 231 231 THR THR C . n 
C 1 236 SER 236 232 232 SER SER C . n 
C 1 237 MET 237 233 233 MET MET C . n 
C 1 238 PRO 238 234 234 PRO PRO C . n 
C 1 239 ASP 239 235 235 ASP ASP C . n 
C 1 240 TYR 240 236 236 TYR TYR C . n 
C 1 241 LYS 241 237 237 LYS LYS C . n 
C 1 242 PRO 242 238 238 PRO PRO C . n 
C 1 243 SER 243 239 239 SER SER C . n 
C 1 244 PHE 244 240 240 PHE PHE C . n 
C 1 245 PRO 245 241 241 PRO PRO C . n 
C 1 246 LYS 246 242 242 LYS LYS C . n 
C 1 247 TRP 247 243 243 TRP TRP C . n 
C 1 248 ALA 248 244 244 ALA ALA C . n 
C 1 249 ARG 249 245 245 ARG ARG C . n 
C 1 250 GLN 250 246 246 GLN GLN C . n 
C 1 251 ASP 251 247 247 ASP ASP C . n 
C 1 252 PHE 252 248 248 PHE PHE C . n 
C 1 253 SER 253 249 249 SER SER C . n 
C 1 254 LYS 254 250 250 LYS LYS C . n 
C 1 255 VAL 255 251 251 VAL VAL C . n 
C 1 256 VAL 256 252 252 VAL VAL C . n 
C 1 257 PRO 257 253 253 PRO PRO C . n 
C 1 258 PRO 258 254 254 PRO PRO C . n 
C 1 259 LEU 259 255 255 LEU LEU C . n 
C 1 260 ASP 260 256 256 ASP ASP C . n 
C 1 261 GLU 261 257 257 GLU GLU C . n 
C 1 262 ASP 262 258 258 ASP ASP C . n 
C 1 263 GLY 263 259 259 GLY GLY C . n 
C 1 264 ARG 264 260 260 ARG ARG C . n 
C 1 265 SER 265 261 261 SER SER C . n 
C 1 266 LEU 266 262 262 LEU LEU C . n 
C 1 267 LEU 267 263 263 LEU LEU C . n 
C 1 268 SER 268 264 264 SER SER C . n 
C 1 269 GLN 269 265 265 GLN GLN C . n 
C 1 270 MET 270 266 266 MET MET C . n 
C 1 271 LEU 271 267 267 LEU LEU C . n 
C 1 272 HIS 272 268 268 HIS HIS C . n 
C 1 273 TYR 273 269 269 TYR TYR C . n 
C 1 274 ASP 274 270 270 ASP ASP C . n 
C 1 275 PRO 275 271 271 PRO PRO C . n 
C 1 276 ASN 276 272 272 ASN ASN C . n 
C 1 277 LYS 277 273 273 LYS LYS C . n 
C 1 278 ARG 278 274 274 ARG ARG C . n 
C 1 279 ILE 279 275 275 ILE ILE C . n 
C 1 280 SER 280 276 276 SER SER C . n 
C 1 281 ALA 281 277 277 ALA ALA C . n 
C 1 282 LYS 282 278 278 LYS LYS C . n 
C 1 283 ALA 283 279 279 ALA ALA C . n 
C 1 284 ALA 284 280 280 ALA ALA C . n 
C 1 285 LEU 285 281 281 LEU LEU C . n 
C 1 286 ALA 286 282 282 ALA ALA C . n 
C 1 287 HIS 287 283 283 HIS HIS C . n 
C 1 288 PRO 288 284 284 PRO PRO C . n 
C 1 289 PHE 289 285 285 PHE PHE C . n 
C 1 290 PHE 290 286 286 PHE PHE C . n 
C 1 291 GLN 291 287 287 GLN GLN C . n 
C 1 292 ASP 292 288 288 ASP ASP C . n 
C 1 293 VAL 293 289 289 VAL VAL C . n 
C 1 294 THR 294 290 290 THR THR C . n 
C 1 295 LYS 295 291 291 LYS LYS C . n 
C 1 296 PRO 296 292 292 PRO PRO C . n 
C 1 297 VAL 297 293 293 VAL VAL C . n 
C 1 298 PRO 298 294 294 PRO PRO C . n 
C 1 299 HIS 299 295 295 HIS HIS C . n 
C 1 300 LEU 300 296 296 LEU LEU C . n 
C 1 301 ARG 301 297 ?   ?   ?   C . n 
C 1 302 LEU 302 298 ?   ?   ?   C . n 
D 2 1   GLY 1   171 171 GLY GLY D . n 
D 2 2   VAL 2   172 172 VAL VAL D . n 
D 2 3   ASN 3   173 173 ASN ASN D . n 
D 2 4   GLU 4   174 174 GLU GLU D . n 
D 2 5   VAL 5   175 175 VAL VAL D . n 
D 2 6   PRO 6   176 176 PRO PRO D . n 
D 2 7   ASP 7   177 177 ASP ASP D . n 
D 2 8   TYR 8   178 178 TYR TYR D . n 
D 2 9   HIS 9   179 179 HIS HIS D . n 
D 2 10  GLU 10  180 180 GLU GLU D . n 
D 2 11  ASP 11  181 181 ASP ASP D . n 
D 2 12  ILE 12  182 182 ILE ILE D . n 
D 2 13  HIS 13  183 183 HIS HIS D . n 
D 2 14  THR 14  184 184 THR THR D . n 
D 2 15  TYR 15  185 185 TYR TYR D . n 
D 2 16  LEU 16  186 186 LEU LEU D . n 
D 2 17  ARG 17  187 187 ARG ARG D . n 
D 2 18  GLU 18  188 188 GLU GLU D . n 
D 2 19  MET 19  189 189 MET MET D . n 
D 2 20  GLU 20  190 190 GLU GLU D . n 
D 2 21  VAL 21  191 191 VAL VAL D . n 
D 2 22  LYS 22  192 192 LYS LYS D . n 
D 2 23  CYS 23  193 193 CYS CYS D . n 
D 2 24  LYS 24  194 194 LYS LYS D . n 
D 2 25  PRO 25  195 195 PRO PRO D . n 
D 2 26  LYS 26  196 196 LYS LYS D . n 
D 2 27  VAL 27  197 197 VAL VAL D . n 
D 2 28  GLY 28  198 198 GLY GLY D . n 
D 2 29  TYR 29  199 199 TYR TYR D . n 
D 2 30  MET 30  200 200 MET MET D . n 
D 2 31  LYS 31  201 201 LYS LYS D . n 
D 2 32  LYS 32  202 202 LYS LYS D . n 
D 2 33  GLN 33  203 203 GLN GLN D . n 
D 2 34  PRO 34  204 204 PRO PRO D . n 
D 2 35  ASP 35  205 205 ASP ASP D . n 
D 2 36  ILE 36  206 206 ILE ILE D . n 
D 2 37  THR 37  207 207 THR THR D . n 
D 2 38  ASN 38  208 208 ASN ASN D . n 
D 2 39  SER 39  209 209 SER SER D . n 
D 2 40  MET 40  210 210 MET MET D . n 
D 2 41  ARG 41  211 211 ARG ARG D . n 
D 2 42  ALA 42  212 212 ALA ALA D . n 
D 2 43  ILE 43  213 213 ILE ILE D . n 
D 2 44  LEU 44  214 214 LEU LEU D . n 
D 2 45  VAL 45  215 215 VAL VAL D . n 
D 2 46  ASP 46  216 216 ASP ASP D . n 
D 2 47  TRP 47  217 217 TRP TRP D . n 
D 2 48  LEU 48  218 218 LEU LEU D . n 
D 2 49  VAL 49  219 219 VAL VAL D . n 
D 2 50  GLU 50  220 220 GLU GLU D . n 
D 2 51  VAL 51  221 221 VAL VAL D . n 
D 2 52  GLY 52  222 222 GLY GLY D . n 
D 2 53  GLU 53  223 223 GLU GLU D . n 
D 2 54  GLU 54  224 224 GLU GLU D . n 
D 2 55  TYR 55  225 225 TYR TYR D . n 
D 2 56  LYS 56  226 226 LYS LYS D . n 
D 2 57  LEU 57  227 227 LEU LEU D . n 
D 2 58  GLN 58  228 228 GLN GLN D . n 
D 2 59  ASN 59  229 229 ASN ASN D . n 
D 2 60  GLU 60  230 230 GLU GLU D . n 
D 2 61  THR 61  231 231 THR THR D . n 
D 2 62  LEU 62  232 232 LEU LEU D . n 
D 2 63  HIS 63  233 233 HIS HIS D . n 
D 2 64  LEU 64  234 234 LEU LEU D . n 
D 2 65  ALA 65  235 235 ALA ALA D . n 
D 2 66  VAL 66  236 236 VAL VAL D . n 
D 2 67  ASN 67  237 237 ASN ASN D . n 
D 2 68  TYR 68  238 238 TYR TYR D . n 
D 2 69  ILE 69  239 239 ILE ILE D . n 
D 2 70  ASP 70  240 240 ASP ASP D . n 
D 2 71  ARG 71  241 241 ARG ARG D . n 
D 2 72  PHE 72  242 242 PHE PHE D . n 
D 2 73  LEU 73  243 243 LEU LEU D . n 
D 2 74  SER 74  244 244 SER SER D . n 
D 2 75  SER 75  245 245 SER SER D . n 
D 2 76  MET 76  246 246 MET MET D . n 
D 2 77  SER 77  247 247 SER SER D . n 
D 2 78  VAL 78  248 248 VAL VAL D . n 
D 2 79  LEU 79  249 249 LEU LEU D . n 
D 2 80  ARG 80  250 250 ARG ARG D . n 
D 2 81  GLY 81  251 251 GLY GLY D . n 
D 2 82  LYS 82  252 252 LYS LYS D . n 
D 2 83  LEU 83  253 253 LEU LEU D . n 
D 2 84  GLN 84  254 254 GLN GLN D . n 
D 2 85  LEU 85  255 255 LEU LEU D . n 
D 2 86  VAL 86  256 256 VAL VAL D . n 
D 2 87  GLY 87  257 257 GLY GLY D . n 
D 2 88  THR 88  258 258 THR THR D . n 
D 2 89  ALA 89  259 259 ALA ALA D . n 
D 2 90  ALA 90  260 260 ALA ALA D . n 
D 2 91  MET 91  261 261 MET MET D . n 
D 2 92  LEU 92  262 262 LEU LEU D . n 
D 2 93  LEU 93  263 263 LEU LEU D . n 
D 2 94  ALA 94  264 264 ALA ALA D . n 
D 2 95  SER 95  265 265 SER SER D . n 
D 2 96  LYS 96  266 266 LYS LYS D . n 
D 2 97  PHE 97  267 267 PHE PHE D . n 
D 2 98  GLU 98  268 268 GLU GLU D . n 
D 2 99  GLU 99  269 269 GLU GLU D . n 
D 2 100 ILE 100 270 270 ILE ILE D . n 
D 2 101 TYR 101 271 271 TYR TYR D . n 
D 2 102 PRO 102 272 272 PRO PRO D . n 
D 2 103 PRO 103 273 273 PRO PRO D . n 
D 2 104 GLU 104 274 274 GLU GLU D . n 
D 2 105 VAL 105 275 275 VAL VAL D . n 
D 2 106 ALA 106 276 276 ALA ALA D . n 
D 2 107 GLU 107 277 277 GLU GLU D . n 
D 2 108 PHE 108 278 278 PHE PHE D . n 
D 2 109 VAL 109 279 279 VAL VAL D . n 
D 2 110 TYR 110 280 280 TYR TYR D . n 
D 2 111 ILE 111 281 281 ILE ILE D . n 
D 2 112 THR 112 282 282 THR THR D . n 
D 2 113 ASP 113 283 283 ASP ASP D . n 
D 2 114 ASP 114 284 284 ASP ASP D . n 
D 2 115 THR 115 285 285 THR THR D . n 
D 2 116 TYR 116 286 286 TYR TYR D . n 
D 2 117 THR 117 287 287 THR THR D . n 
D 2 118 LYS 118 288 288 LYS LYS D . n 
D 2 119 LYS 119 289 289 LYS LYS D . n 
D 2 120 GLN 120 290 290 GLN GLN D . n 
D 2 121 VAL 121 291 291 VAL VAL D . n 
D 2 122 LEU 122 292 292 LEU LEU D . n 
D 2 123 ARG 123 293 293 ARG ARG D . n 
D 2 124 MET 124 294 294 MET MET D . n 
D 2 125 GLU 125 295 295 GLU GLU D . n 
D 2 126 HIS 126 296 296 HIS HIS D . n 
D 2 127 LEU 127 297 297 LEU LEU D . n 
D 2 128 VAL 128 298 298 VAL VAL D . n 
D 2 129 LEU 129 299 299 LEU LEU D . n 
D 2 130 LYS 130 300 300 LYS LYS D . n 
D 2 131 VAL 131 301 301 VAL VAL D . n 
D 2 132 LEU 132 302 302 LEU LEU D . n 
D 2 133 ALA 133 303 303 ALA ALA D . n 
D 2 134 PHE 134 304 304 PHE PHE D . n 
D 2 135 ASP 135 305 305 ASP ASP D . n 
D 2 136 LEU 136 306 306 LEU LEU D . n 
D 2 137 ALA 137 307 307 ALA ALA D . n 
D 2 138 ALA 138 308 308 ALA ALA D . n 
D 2 139 PRO 139 309 309 PRO PRO D . n 
D 2 140 THR 140 310 310 THR THR D . n 
D 2 141 ILE 141 311 311 ILE ILE D . n 
D 2 142 ASN 142 312 312 ASN ASN D . n 
D 2 143 GLN 143 313 313 GLN GLN D . n 
D 2 144 PHE 144 314 314 PHE PHE D . n 
D 2 145 LEU 145 315 315 LEU LEU D . n 
D 2 146 THR 146 316 316 THR THR D . n 
D 2 147 GLN 147 317 317 GLN GLN D . n 
D 2 148 TYR 148 318 318 TYR TYR D . n 
D 2 149 PHE 149 319 319 PHE PHE D . n 
D 2 150 LEU 150 320 320 LEU LEU D . n 
D 2 151 HIS 151 321 321 HIS HIS D . n 
D 2 152 GLN 152 322 322 GLN GLN D . n 
D 2 153 GLN 153 323 323 GLN GLN D . n 
D 2 154 PRO 154 324 324 PRO PRO D . n 
D 2 155 ALA 155 325 325 ALA ALA D . n 
D 2 156 ASN 156 326 326 ASN ASN D . n 
D 2 157 CYS 157 327 327 CYS CYS D . n 
D 2 158 LYS 158 328 328 LYS LYS D . n 
D 2 159 VAL 159 329 329 VAL VAL D . n 
D 2 160 GLU 160 330 330 GLU GLU D . n 
D 2 161 SER 161 331 331 SER SER D . n 
D 2 162 LEU 162 332 332 LEU LEU D . n 
D 2 163 ALA 163 333 333 ALA ALA D . n 
D 2 164 MET 164 334 334 MET MET D . n 
D 2 165 PHE 165 335 335 PHE PHE D . n 
D 2 166 LEU 166 336 336 LEU LEU D . n 
D 2 167 GLY 167 337 337 GLY GLY D . n 
D 2 168 GLU 168 338 338 GLU GLU D . n 
D 2 169 LEU 169 339 339 LEU LEU D . n 
D 2 170 SER 170 340 340 SER SER D . n 
D 2 171 LEU 171 341 341 LEU LEU D . n 
D 2 172 ILE 172 342 342 ILE ILE D . n 
D 2 173 ASP 173 343 343 ASP ASP D . n 
D 2 174 ALA 174 344 344 ALA ALA D . n 
D 2 175 ASP 175 345 345 ASP ASP D . n 
D 2 176 PRO 176 346 346 PRO PRO D . n 
D 2 177 TYR 177 347 347 TYR TYR D . n 
D 2 178 LEU 178 348 348 LEU LEU D . n 
D 2 179 LYS 179 349 349 LYS LYS D . n 
D 2 180 TYR 180 350 350 TYR TYR D . n 
D 2 181 LEU 181 351 351 LEU LEU D . n 
D 2 182 PRO 182 352 352 PRO PRO D . n 
D 2 183 SER 183 353 353 SER SER D . n 
D 2 184 VAL 184 354 354 VAL VAL D . n 
D 2 185 ILE 185 355 355 ILE ILE D . n 
D 2 186 ALA 186 356 356 ALA ALA D . n 
D 2 187 ALA 187 357 357 ALA ALA D . n 
D 2 188 ALA 188 358 358 ALA ALA D . n 
D 2 189 ALA 189 359 359 ALA ALA D . n 
D 2 190 PHE 190 360 360 PHE PHE D . n 
D 2 191 HIS 191 361 361 HIS HIS D . n 
D 2 192 LEU 192 362 362 LEU LEU D . n 
D 2 193 ALA 193 363 363 ALA ALA D . n 
D 2 194 LEU 194 364 364 LEU LEU D . n 
D 2 195 TYR 195 365 365 TYR TYR D . n 
D 2 196 THR 196 366 366 THR THR D . n 
D 2 197 VAL 197 367 367 VAL VAL D . n 
D 2 198 THR 198 368 368 THR THR D . n 
D 2 199 GLY 199 369 369 GLY GLY D . n 
D 2 200 GLN 200 370 370 GLN GLN D . n 
D 2 201 SER 201 371 371 SER SER D . n 
D 2 202 TRP 202 372 372 TRP TRP D . n 
D 2 203 PRO 203 373 373 PRO PRO D . n 
D 2 204 GLU 204 374 374 GLU GLU D . n 
D 2 205 SER 205 375 375 SER SER D . n 
D 2 206 LEU 206 376 376 LEU LEU D . n 
D 2 207 VAL 207 377 377 VAL VAL D . n 
D 2 208 GLN 208 378 378 GLN GLN D . n 
D 2 209 LYS 209 379 379 LYS LYS D . n 
D 2 210 THR 210 380 380 THR THR D . n 
D 2 211 GLY 211 381 381 GLY GLY D . n 
D 2 212 TYR 212 382 382 TYR TYR D . n 
D 2 213 THR 213 383 383 THR THR D . n 
D 2 214 LEU 214 384 384 LEU LEU D . n 
D 2 215 GLU 215 385 385 GLU GLU D . n 
D 2 216 THR 216 386 386 THR THR D . n 
D 2 217 LEU 217 387 387 LEU LEU D . n 
D 2 218 LYS 218 388 388 LYS LYS D . n 
D 2 219 PRO 219 389 389 PRO PRO D . n 
D 2 220 CYS 220 390 390 CYS CYS D . n 
D 2 221 LEU 221 391 391 LEU LEU D . n 
D 2 222 LEU 222 392 392 LEU LEU D . n 
D 2 223 ASP 223 393 393 ASP ASP D . n 
D 2 224 LEU 224 394 394 LEU LEU D . n 
D 2 225 HIS 225 395 395 HIS HIS D . n 
D 2 226 GLN 226 396 396 GLN GLN D . n 
D 2 227 THR 227 397 397 THR THR D . n 
D 2 228 TYR 228 398 398 TYR TYR D . n 
D 2 229 LEU 229 399 399 LEU LEU D . n 
D 2 230 ARG 230 400 400 ARG ARG D . n 
D 2 231 ALA 231 401 401 ALA ALA D . n 
D 2 232 PRO 232 402 402 PRO PRO D . n 
D 2 233 GLN 233 403 403 GLN GLN D . n 
D 2 234 HIS 234 404 404 HIS HIS D . n 
D 2 235 ALA 235 405 405 ALA ALA D . n 
D 2 236 GLN 236 406 406 GLN GLN D . n 
D 2 237 GLN 237 407 407 GLN GLN D . n 
D 2 238 SER 238 408 408 SER SER D . n 
D 2 239 ILE 239 409 409 ILE ILE D . n 
D 2 240 ARG 240 410 410 ARG ARG D . n 
D 2 241 GLU 241 411 411 GLU GLU D . n 
D 2 242 LYS 242 412 412 LYS LYS D . n 
D 2 243 TYR 243 413 413 TYR TYR D . n 
D 2 244 LYS 244 414 414 LYS LYS D . n 
D 2 245 ASN 245 415 415 ASN ASN D . n 
D 2 246 SER 246 416 416 SER SER D . n 
D 2 247 LYS 247 417 417 LYS LYS D . n 
D 2 248 TYR 248 418 418 TYR TYR D . n 
D 2 249 HIS 249 419 419 HIS HIS D . n 
D 2 250 GLY 250 420 420 GLY GLY D . n 
D 2 251 VAL 251 421 421 VAL VAL D . n 
D 2 252 SER 252 422 422 SER SER D . n 
D 2 253 LEU 253 423 423 LEU LEU D . n 
D 2 254 LEU 254 424 424 LEU LEU D . n 
D 2 255 ASN 255 425 425 ASN ASN D . n 
D 2 256 PRO 256 426 426 PRO PRO D . n 
D 2 257 PRO 257 427 427 PRO PRO D . n 
D 2 258 GLU 258 428 428 GLU GLU D . n 
D 2 259 THR 259 429 429 THR THR D . n 
D 2 260 LEU 260 430 430 LEU LEU D . n 
D 2 261 ASN 261 431 431 ASN ASN D . n 
D 2 262 VAL 262 432 432 VAL VAL D . n 
D 2 263 HIS 263 433 ?   ?   ?   D . n 
D 2 264 HIS 264 434 ?   ?   ?   D . n 
D 2 265 HIS 265 435 ?   ?   ?   D . n 
D 2 266 HIS 266 436 ?   ?   ?   D . n 
D 2 267 HIS 267 437 ?   ?   ?   D . n 
D 2 268 HIS 268 438 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        IJL 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   IJL 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 IJL 1   301 598 IJL DRG A . 
F 3 IJL 1   302 600 IJL DRG A . 
G 3 IJL 1   301 478 IJL DRG C . 
H 4 HOH 1   401 408 HOH HOH A . 
H 4 HOH 2   402 179 HOH HOH A . 
H 4 HOH 3   403 479 HOH HOH A . 
H 4 HOH 4   404 425 HOH HOH A . 
H 4 HOH 5   405 475 HOH HOH A . 
H 4 HOH 6   406 467 HOH HOH A . 
H 4 HOH 7   407 410 HOH HOH A . 
H 4 HOH 8   408 413 HOH HOH A . 
H 4 HOH 9   409 404 HOH HOH A . 
H 4 HOH 10  410 461 HOH HOH A . 
H 4 HOH 11  411 465 HOH HOH A . 
H 4 HOH 12  412 441 HOH HOH A . 
H 4 HOH 13  413 474 HOH HOH A . 
H 4 HOH 14  414 430 HOH HOH A . 
H 4 HOH 15  415 436 HOH HOH A . 
H 4 HOH 16  416 428 HOH HOH A . 
H 4 HOH 17  417 440 HOH HOH A . 
H 4 HOH 18  418 525 HOH HOH A . 
H 4 HOH 19  419 522 HOH HOH A . 
H 4 HOH 20  420 540 HOH HOH A . 
H 4 HOH 21  421 464 HOH HOH A . 
H 4 HOH 22  422 420 HOH HOH A . 
H 4 HOH 23  423 477 HOH HOH A . 
H 4 HOH 24  424 417 HOH HOH A . 
H 4 HOH 25  425 432 HOH HOH A . 
H 4 HOH 26  426 451 HOH HOH A . 
H 4 HOH 27  427 483 HOH HOH A . 
H 4 HOH 28  428 468 HOH HOH A . 
H 4 HOH 29  429 427 HOH HOH A . 
H 4 HOH 30  430 470 HOH HOH A . 
H 4 HOH 31  431 33  HOH HOH A . 
H 4 HOH 32  432 525 HOH HOH A . 
H 4 HOH 33  433 450 HOH HOH A . 
H 4 HOH 34  434 407 HOH HOH A . 
H 4 HOH 35  435 504 HOH HOH A . 
H 4 HOH 36  436 438 HOH HOH A . 
H 4 HOH 37  437 523 HOH HOH A . 
H 4 HOH 38  438 544 HOH HOH A . 
H 4 HOH 39  439 445 HOH HOH A . 
H 4 HOH 40  440 409 HOH HOH A . 
H 4 HOH 41  441 45  HOH HOH A . 
H 4 HOH 42  442 480 HOH HOH A . 
H 4 HOH 43  443 448 HOH HOH A . 
H 4 HOH 44  444 478 HOH HOH A . 
H 4 HOH 45  445 510 HOH HOH A . 
H 4 HOH 46  446 439 HOH HOH A . 
H 4 HOH 47  447 435 HOH HOH A . 
H 4 HOH 48  448 502 HOH HOH A . 
H 4 HOH 49  449 433 HOH HOH A . 
H 4 HOH 50  450 456 HOH HOH A . 
H 4 HOH 51  451 447 HOH HOH A . 
H 4 HOH 52  452 528 HOH HOH A . 
H 4 HOH 53  453 553 HOH HOH A . 
H 4 HOH 54  454 429 HOH HOH A . 
H 4 HOH 55  455 554 HOH HOH A . 
H 4 HOH 56  456 550 HOH HOH A . 
H 4 HOH 57  457 556 HOH HOH A . 
H 4 HOH 58  458 490 HOH HOH A . 
H 4 HOH 59  459 431 HOH HOH A . 
H 4 HOH 60  460 507 HOH HOH A . 
H 4 HOH 61  461 485 HOH HOH A . 
H 4 HOH 62  462 482 HOH HOH A . 
H 4 HOH 63  463 530 HOH HOH A . 
H 4 HOH 64  464 552 HOH HOH A . 
H 4 HOH 65  465 500 HOH HOH A . 
H 4 HOH 66  466 495 HOH HOH A . 
H 4 HOH 67  467 524 HOH HOH A . 
H 4 HOH 68  468 18  HOH HOH A . 
H 4 HOH 69  469 126 HOH HOH A . 
H 4 HOH 70  470 503 HOH HOH A . 
H 4 HOH 71  471 546 HOH HOH A . 
H 4 HOH 72  472 535 HOH HOH A . 
H 4 HOH 73  473 571 HOH HOH A . 
H 4 HOH 74  474 625 HOH HOH A . 
H 4 HOH 75  475 569 HOH HOH A . 
H 4 HOH 76  476 573 HOH HOH A . 
H 4 HOH 77  477 570 HOH HOH A . 
H 4 HOH 78  478 576 HOH HOH A . 
H 4 HOH 79  479 542 HOH HOH A . 
H 4 HOH 80  480 559 HOH HOH A . 
H 4 HOH 81  481 575 HOH HOH A . 
H 4 HOH 82  482 560 HOH HOH A . 
H 4 HOH 83  483 551 HOH HOH A . 
H 4 HOH 84  484 557 HOH HOH A . 
H 4 HOH 85  485 658 HOH HOH A . 
H 4 HOH 86  486 437 HOH HOH A . 
H 4 HOH 87  487 418 HOH HOH A . 
H 4 HOH 88  488 565 HOH HOH A . 
H 4 HOH 89  489 583 HOH HOH A . 
H 4 HOH 90  490 567 HOH HOH A . 
H 4 HOH 91  491 594 HOH HOH A . 
H 4 HOH 92  492 588 HOH HOH A . 
I 4 HOH 1   501 537 HOH HOH B . 
I 4 HOH 2   502 507 HOH HOH B . 
I 4 HOH 3   503 523 HOH HOH B . 
I 4 HOH 4   504 410 HOH HOH B . 
I 4 HOH 5   505 613 HOH HOH B . 
I 4 HOH 6   506 415 HOH HOH B . 
I 4 HOH 7   507 508 HOH HOH B . 
I 4 HOH 8   508 510 HOH HOH B . 
I 4 HOH 9   509 506 HOH HOH B . 
I 4 HOH 10  510 538 HOH HOH B . 
I 4 HOH 11  511 555 HOH HOH B . 
I 4 HOH 12  512 563 HOH HOH B . 
I 4 HOH 13  513 534 HOH HOH B . 
I 4 HOH 14  514 532 HOH HOH B . 
I 4 HOH 15  515 556 HOH HOH B . 
I 4 HOH 16  516 622 HOH HOH B . 
I 4 HOH 17  517 66  HOH HOH B . 
I 4 HOH 18  518 572 HOH HOH B . 
I 4 HOH 19  519 524 HOH HOH B . 
I 4 HOH 20  520 547 HOH HOH B . 
I 4 HOH 21  521 542 HOH HOH B . 
I 4 HOH 22  522 571 HOH HOH B . 
I 4 HOH 23  523 545 HOH HOH B . 
I 4 HOH 24  524 570 HOH HOH B . 
I 4 HOH 25  525 558 HOH HOH B . 
I 4 HOH 26  526 459 HOH HOH B . 
I 4 HOH 27  527 599 HOH HOH B . 
I 4 HOH 28  528 509 HOH HOH B . 
I 4 HOH 29  529 531 HOH HOH B . 
I 4 HOH 30  530 580 HOH HOH B . 
I 4 HOH 31  531 600 HOH HOH B . 
I 4 HOH 32  532 567 HOH HOH B . 
I 4 HOH 33  533 505 HOH HOH B . 
I 4 HOH 34  534 574 HOH HOH B . 
I 4 HOH 35  535 520 HOH HOH B . 
I 4 HOH 36  536 585 HOH HOH B . 
I 4 HOH 37  537 593 HOH HOH B . 
I 4 HOH 38  538 589 HOH HOH B . 
I 4 HOH 39  539 595 HOH HOH B . 
I 4 HOH 40  540 639 HOH HOH B . 
I 4 HOH 41  541 554 HOH HOH B . 
I 4 HOH 42  542 607 HOH HOH B . 
I 4 HOH 43  543 566 HOH HOH B . 
I 4 HOH 44  544 548 HOH HOH B . 
I 4 HOH 45  545 609 HOH HOH B . 
I 4 HOH 46  546 564 HOH HOH B . 
I 4 HOH 47  547 525 HOH HOH B . 
I 4 HOH 48  548 583 HOH HOH B . 
I 4 HOH 49  549 511 HOH HOH B . 
I 4 HOH 50  550 522 HOH HOH B . 
I 4 HOH 51  551 569 HOH HOH B . 
I 4 HOH 52  552 612 HOH HOH B . 
I 4 HOH 53  553 596 HOH HOH B . 
I 4 HOH 54  554 615 HOH HOH B . 
I 4 HOH 55  555 633 HOH HOH B . 
I 4 HOH 56  556 656 HOH HOH B . 
I 4 HOH 57  557 601 HOH HOH B . 
I 4 HOH 58  558 588 HOH HOH B . 
I 4 HOH 59  559 529 HOH HOH B . 
I 4 HOH 60  560 650 HOH HOH B . 
I 4 HOH 61  561 648 HOH HOH B . 
I 4 HOH 62  562 630 HOH HOH B . 
I 4 HOH 63  563 27  HOH HOH B . 
I 4 HOH 64  564 619 HOH HOH B . 
I 4 HOH 65  565 605 HOH HOH B . 
I 4 HOH 66  566 516 HOH HOH B . 
I 4 HOH 67  567 638 HOH HOH B . 
I 4 HOH 68  568 241 HOH HOH B . 
I 4 HOH 69  569 598 HOH HOH B . 
I 4 HOH 70  570 627 HOH HOH B . 
I 4 HOH 71  571 637 HOH HOH B . 
I 4 HOH 72  572 528 HOH HOH B . 
I 4 HOH 73  573 592 HOH HOH B . 
I 4 HOH 74  574 631 HOH HOH B . 
I 4 HOH 75  575 582 HOH HOH B . 
I 4 HOH 76  576 604 HOH HOH B . 
I 4 HOH 77  577 644 HOH HOH B . 
I 4 HOH 78  578 629 HOH HOH B . 
I 4 HOH 79  579 617 HOH HOH B . 
I 4 HOH 80  580 632 HOH HOH B . 
I 4 HOH 81  581 641 HOH HOH B . 
I 4 HOH 82  582 636 HOH HOH B . 
I 4 HOH 83  583 634 HOH HOH B . 
I 4 HOH 84  584 649 HOH HOH B . 
I 4 HOH 85  585 213 HOH HOH B . 
I 4 HOH 86  586 640 HOH HOH B . 
I 4 HOH 87  587 442 HOH HOH B . 
I 4 HOH 88  588 539 HOH HOH B . 
I 4 HOH 89  589 665 HOH HOH B . 
I 4 HOH 90  590 251 HOH HOH B . 
I 4 HOH 91  591 587 HOH HOH B . 
I 4 HOH 92  592 667 HOH HOH B . 
I 4 HOH 93  593 674 HOH HOH B . 
I 4 HOH 94  594 668 HOH HOH B . 
I 4 HOH 95  595 676 HOH HOH B . 
I 4 HOH 96  596 593 HOH HOH B . 
I 4 HOH 97  597 675 HOH HOH B . 
I 4 HOH 98  598 672 HOH HOH B . 
I 4 HOH 99  599 679 HOH HOH B . 
I 4 HOH 100 600 680 HOH HOH B . 
I 4 HOH 101 601 677 HOH HOH B . 
I 4 HOH 102 602 684 HOH HOH B . 
J 4 HOH 1   401 428 HOH HOH C . 
J 4 HOH 2   402 28  HOH HOH C . 
J 4 HOH 3   403 407 HOH HOH C . 
J 4 HOH 4   404 418 HOH HOH C . 
J 4 HOH 5   405 109 HOH HOH C . 
J 4 HOH 6   406 425 HOH HOH C . 
J 4 HOH 7   407 414 HOH HOH C . 
J 4 HOH 8   408 433 HOH HOH C . 
J 4 HOH 9   409 430 HOH HOH C . 
J 4 HOH 10  410 453 HOH HOH C . 
J 4 HOH 11  411 460 HOH HOH C . 
J 4 HOH 12  412 40  HOH HOH C . 
J 4 HOH 13  413 434 HOH HOH C . 
J 4 HOH 14  414 432 HOH HOH C . 
J 4 HOH 15  415 424 HOH HOH C . 
J 4 HOH 16  416 440 HOH HOH C . 
J 4 HOH 17  417 422 HOH HOH C . 
J 4 HOH 18  418 406 HOH HOH C . 
J 4 HOH 19  419 439 HOH HOH C . 
J 4 HOH 20  420 450 HOH HOH C . 
J 4 HOH 21  421 419 HOH HOH C . 
J 4 HOH 22  422 438 HOH HOH C . 
J 4 HOH 23  423 427 HOH HOH C . 
J 4 HOH 24  424 44  HOH HOH C . 
J 4 HOH 25  425 20  HOH HOH C . 
J 4 HOH 26  426 452 HOH HOH C . 
J 4 HOH 27  427 437 HOH HOH C . 
J 4 HOH 28  428 105 HOH HOH C . 
J 4 HOH 29  429 23  HOH HOH C . 
J 4 HOH 30  430 17  HOH HOH C . 
J 4 HOH 31  431 423 HOH HOH C . 
J 4 HOH 32  432 403 HOH HOH C . 
J 4 HOH 33  433 458 HOH HOH C . 
J 4 HOH 34  434 468 HOH HOH C . 
J 4 HOH 35  435 39  HOH HOH C . 
J 4 HOH 36  436 465 HOH HOH C . 
J 4 HOH 37  437 123 HOH HOH C . 
J 4 HOH 38  438 12  HOH HOH C . 
J 4 HOH 39  439 464 HOH HOH C . 
J 4 HOH 40  440 411 HOH HOH C . 
J 4 HOH 41  441 474 HOH HOH C . 
J 4 HOH 42  442 477 HOH HOH C . 
J 4 HOH 43  443 16  HOH HOH C . 
K 4 HOH 1   501 501 HOH HOH D . 
K 4 HOH 2   502 506 HOH HOH D . 
K 4 HOH 3   503 522 HOH HOH D . 
K 4 HOH 4   504 504 HOH HOH D . 
K 4 HOH 5   505 513 HOH HOH D . 
K 4 HOH 6   506 544 HOH HOH D . 
K 4 HOH 7   507 524 HOH HOH D . 
K 4 HOH 8   508 547 HOH HOH D . 
K 4 HOH 9   509 505 HOH HOH D . 
K 4 HOH 10  510 521 HOH HOH D . 
K 4 HOH 11  511 512 HOH HOH D . 
K 4 HOH 12  512 532 HOH HOH D . 
K 4 HOH 13  513 529 HOH HOH D . 
K 4 HOH 14  514 41  HOH HOH D . 
K 4 HOH 15  515 555 HOH HOH D . 
K 4 HOH 16  516 507 HOH HOH D . 
K 4 HOH 17  517 508 HOH HOH D . 
K 4 HOH 18  518 530 HOH HOH D . 
K 4 HOH 19  519 520 HOH HOH D . 
K 4 HOH 20  520 539 HOH HOH D . 
K 4 HOH 21  521 527 HOH HOH D . 
K 4 HOH 22  522 15  HOH HOH D . 
K 4 HOH 23  523 567 HOH HOH D . 
K 4 HOH 24  524 32  HOH HOH D . 
K 4 HOH 25  525 534 HOH HOH D . 
K 4 HOH 26  526 511 HOH HOH D . 
K 4 HOH 27  527 537 HOH HOH D . 
K 4 HOH 28  528 554 HOH HOH D . 
K 4 HOH 29  529 43  HOH HOH D . 
K 4 HOH 30  530 516 HOH HOH D . 
K 4 HOH 31  531 183 HOH HOH D . 
K 4 HOH 32  532 565 HOH HOH D . 
K 4 HOH 33  533 253 HOH HOH D . 
K 4 HOH 34  534 540 HOH HOH D . 
K 4 HOH 35  535 546 HOH HOH D . 
K 4 HOH 36  536 535 HOH HOH D . 
K 4 HOH 37  537 553 HOH HOH D . 
K 4 HOH 38  538 531 HOH HOH D . 
K 4 HOH 39  539 538 HOH HOH D . 
K 4 HOH 40  540 514 HOH HOH D . 
K 4 HOH 41  541 562 HOH HOH D . 
K 4 HOH 42  542 558 HOH HOH D . 
K 4 HOH 43  543 560 HOH HOH D . 
K 4 HOH 44  544 811 HOH HOH D . 
K 4 HOH 45  545 569 HOH HOH D . 
K 4 HOH 46  546 551 HOH HOH D . 
K 4 HOH 47  547 579 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ET1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     73.971 
_cell.length_a_esd                 ? 
_cell.length_b                     133.287 
_cell.length_b_esd                 ? 
_cell.length_c                     147.26 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ET1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ET1 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.78 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.83 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ET1 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.35 
_reflns.d_resolution_low                               133.29 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     55046 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           89.5 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.21 
_reflns.pdbx_Rpim_I_all                                0.078 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.195 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
9.97 133.29 ? 34.8 ? ? ? ? 933  ? ? ? ? ? ? ? ? ? ? ? 12.2 ? ? ? 0.049 0.018 ? 1 1 0.999 ? ? 99.9 ? 0.046 ? ? ? ? ? ? ? ? ? 
2.38 2.42   ? 1.3  ? ? ? ? 4967 ? ? ? ? ? ? ? ? ? ? ? 13   ? ? ? 2.177 0.838 ? 2 1 0.6   ? ? 100  ? 2.006 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -1.717 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            1.242 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.474 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               33.438 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.952 
_refine.correlation_coeff_Fo_to_Fc_free          0.935 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ET1 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.394 
_refine.ls_d_res_low                             73.739 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     50865 
_refine.ls_number_reflns_R_free                  2585 
_refine.ls_number_reflns_R_work                  48280 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    87.481 
_refine.ls_percent_reflns_R_free                 5.082 
_refine.ls_R_factor_all                          0.221 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2281 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2208 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.214 
_refine.ls_wR_factor_R_work                      0.210 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.524 
_refine.pdbx_overall_ESU_R_Free                  0.256 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.9502 
_refine.pdbx_average_fsc_free                    0.9487 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.394 
_refine_hist.d_res_low                        73.739 
_refine_hist.number_atoms_solvent             284 
_refine_hist.number_atoms_total               9344 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9030 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         30 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  9316  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.567  1.848  12660 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 5.865  5.000  1123  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.294 5.000  50    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.872 10.000 1625  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.570 10.000 403   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.101  0.200  1432  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  6992  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.228  0.200  4522  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.314  0.200  6378  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.145  0.200  379   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.337  0.200  79    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.302  0.200  11    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.815  3.183  4498  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.514  5.716  5619  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.115  3.443  4818  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.443  6.185  7041  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 9.548  36.577 14323 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.394  2.456  4249 . 163 3274 80.8896  . 1.177 . . 1.179 . . . . . 1.309 . 20 . 0.785 0.773 1.147 
'X-RAY DIFFRACTION' 2.456  2.523  4108 . 236 3870 99.9513  . 0.519 . . 0.519 . . . . . 0.520 . 20 . 0.913 0.921 0.507 
'X-RAY DIFFRACTION' 2.523  2.596  3975 . 204 3771 100.0000 . 0.304 . . 0.305 . . . . . 0.304 . 20 . 0.944 0.946 0.294 
'X-RAY DIFFRACTION' 2.596  2.676  3952 . 111 2061 54.9595  . 0.293 . . 0.292 . . . . . 0.289 . 20 . 0.942 0.926 0.320 
'X-RAY DIFFRACTION' 2.676  2.764  3785 . 78  1758 48.5073  . 0.271 . . 0.272 . . . . . 0.264 . 20 . 0.950 0.952 0.258 
'X-RAY DIFFRACTION' 2.764  2.861  3671 . 184 3487 100.0000 . 0.268 . . 0.268 . . . . . 0.260 . 20 . 0.955 0.954 0.267 
'X-RAY DIFFRACTION' 2.861  2.969  3554 . 198 3356 100.0000 . 0.255 . . 0.254 . . . . . 0.244 . 20 . 0.959 0.963 0.258 
'X-RAY DIFFRACTION' 2.969  3.090  3421 . 177 3244 100.0000 . 0.250 . . 0.250 . . . . . 0.242 . 20 . 0.963 0.964 0.248 
'X-RAY DIFFRACTION' 3.090  3.227  3279 . 164 3115 100.0000 . 0.245 . . 0.244 . . . . . 0.233 . 20 . 0.966 0.966 0.254 
'X-RAY DIFFRACTION' 3.227  3.384  3156 . 151 3004 99.9683  . 0.229 . . 0.227 . . . . . 0.216 . 20 . 0.970 0.966 0.259 
'X-RAY DIFFRACTION' 3.384  3.567  2987 . 89  1685 59.3907  . 0.203 . . 0.202 . . . . . 0.194 . 20 . 0.977 0.975 0.226 
'X-RAY DIFFRACTION' 3.567  3.782  2836 . 117 2088 77.7504  . 0.190 . . 0.189 . . . . . 0.181 . 20 . 0.978 0.977 0.208 
'X-RAY DIFFRACTION' 3.782  4.043  2693 . 78  1753 67.9911  . 0.179 . . 0.179 . . . . . 0.171 . 20 . 0.980 0.983 0.180 
'X-RAY DIFFRACTION' 4.043  4.366  2505 . 140 2365 100.0000 . 0.158 . . 0.158 . . . . . 0.154 . 20 . 0.985 0.987 0.146 
'X-RAY DIFFRACTION' 4.366  4.781  2307 . 118 2189 100.0000 . 0.159 . . 0.159 . . . . . 0.156 . 20 . 0.984 0.980 0.172 
'X-RAY DIFFRACTION' 4.781  5.342  2115 . 95  2020 100.0000 . 0.175 . . 0.175 . . . . . 0.173 . 20 . 0.983 0.984 0.166 
'X-RAY DIFFRACTION' 5.342  6.163  1885 . 98  1787 100.0000 . 0.213 . . 0.213 . . . . . 0.207 . 20 . 0.977 0.978 0.221 
'X-RAY DIFFRACTION' 6.163  7.535  1600 . 92  1508 100.0000 . 0.209 . . 0.209 . . . . . 0.204 . 20 . 0.978 0.978 0.208 
'X-RAY DIFFRACTION' 7.535  10.601 1274 . 55  1219 100.0000 . 0.152 . . 0.152 . . . . . 0.159 . 20 . 0.987 0.987 0.153 
'X-RAY DIFFRACTION' 10.601 73.739 767  . 37  727  99.6089  . 0.217 . . 0.213 . . . . . 0.238 . 20 . 0.968 0.884 0.306 
# 
_struct.entry_id                     9ET1 
_struct.title                        'CDK2-cyclin A in complex with FragLite 12' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ET1 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CDK2_HUMAN  P24941 ? 1 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
2 UNP CCNA2_BOVIN P30274 ? 2 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ET1 A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
2 2 9ET1 B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
3 1 9ET1 C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
4 2 9ET1 D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ET1 GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  1  
1 9ET1 PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  2  
1 9ET1 GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  3  
1 9ET1 SER A 4   ? UNP P24941 ? ? 'expression tag' 0   4  
2 9ET1 GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 5  
2 9ET1 HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 6  
2 9ET1 HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 7  
2 9ET1 HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 8  
2 9ET1 HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 9  
2 9ET1 HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 10 
2 9ET1 HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 11 
3 9ET1 GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  12 
3 9ET1 PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  13 
3 9ET1 GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  14 
3 9ET1 SER C 4   ? UNP P24941 ? ? 'expression tag' 0   15 
4 9ET1 GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 16 
4 9ET1 HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 17 
4 9ET1 HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 18 
4 9ET1 HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 19 
4 9ET1 HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 20 
4 9ET1 HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 21 
4 9ET1 HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3620  ? 
1 MORE         -15   ? 
1 'SSA (A^2)'  23580 ? 
2 'ABSA (A^2)' 3610  ? 
2 MORE         -15   ? 
2 'SSA (A^2)'  23160 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,H,I 
2 1 C,D,G,J,K   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 4   ? GLU A 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P2  AA2 PRO A 49  ? GLU A 61  ? PRO A 45  GLU A 57  1 ? 13 
HELX_P HELX_P3  AA3 LEU A 91  ? SER A 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P4  AA4 PRO A 104 ? HIS A 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P5  AA5 LYS A 133 ? GLN A 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P6  AA6 THR A 169 ? ARG A 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P7  AA7 ALA A 174 ? LEU A 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P8  AA8 THR A 186 ? ARG A 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P9  AA9 SER A 211 ? GLY A 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P10 AB1 GLY A 233 ? MET A 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P11 AB2 ASP A 251 ? VAL A 255 ? ASP A 247 VAL A 251 5 ? 5  
HELX_P HELX_P12 AB3 ASP A 260 ? LEU A 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P13 AB4 SER A 280 ? LEU A 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P14 AB5 ALA A 286 ? GLN A 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P15 AB6 GLY B 1   ? VAL B 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P16 AB7 TYR B 8   ? CYS B 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P17 AB8 TYR B 29  ? GLN B 33  ? TYR B 199 GLN B 203 5 ? 5  
HELX_P HELX_P18 AB9 THR B 37  ? TYR B 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P19 AC1 GLN B 58  ? MET B 76  ? GLN B 228 MET B 246 1 ? 19 
HELX_P HELX_P20 AC2 LEU B 79  ? GLU B 99  ? LEU B 249 GLU B 269 1 ? 21 
HELX_P HELX_P21 AC3 GLU B 104 ? THR B 112 ? GLU B 274 THR B 282 1 ? 9  
HELX_P HELX_P22 AC4 THR B 117 ? ALA B 133 ? THR B 287 ALA B 303 1 ? 17 
HELX_P HELX_P23 AC5 THR B 140 ? LEU B 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P24 AC6 ASN B 156 ? ASP B 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P25 AC7 ASP B 173 ? LEU B 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P26 AC8 LEU B 181 ? GLY B 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P27 AC9 PRO B 203 ? GLY B 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P28 AD1 THR B 213 ? ARG B 230 ? THR B 383 ARG B 400 1 ? 18 
HELX_P HELX_P29 AD2 ALA B 231 ? HIS B 234 ? ALA B 401 HIS B 404 5 ? 4  
HELX_P HELX_P30 AD3 GLN B 237 ? TYR B 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P31 AD4 LYS B 244 ? HIS B 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P32 AD5 GLY B 250 ? LEU B 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P33 AD6 PRO C 49  ? GLU C 61  ? PRO C 45  GLU C 57  1 ? 13 
HELX_P HELX_P34 AD7 LEU C 91  ? SER C 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P35 AD8 PRO C 104 ? HIS C 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P36 AD9 LYS C 133 ? GLN C 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P37 AE1 THR C 169 ? ARG C 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P38 AE2 ALA C 174 ? LEU C 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P39 AE3 THR C 186 ? ARG C 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P40 AE4 SER C 211 ? GLY C 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P41 AE5 GLY C 233 ? MET C 237 ? GLY C 229 MET C 233 5 ? 5  
HELX_P HELX_P42 AE6 ASP C 251 ? VAL C 256 ? ASP C 247 VAL C 252 1 ? 6  
HELX_P HELX_P43 AE7 ASP C 260 ? LEU C 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P44 AE8 SER C 280 ? LEU C 285 ? SER C 276 LEU C 281 1 ? 6  
HELX_P HELX_P45 AE9 ALA C 286 ? GLN C 291 ? ALA C 282 GLN C 287 5 ? 6  
HELX_P HELX_P46 AF1 GLY D 1   ? VAL D 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P47 AF2 TYR D 8   ? CYS D 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P48 AF3 GLY D 28  ? GLN D 33  ? GLY D 198 GLN D 203 1 ? 6  
HELX_P HELX_P49 AF4 THR D 37  ? TYR D 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P50 AF5 GLN D 58  ? SER D 74  ? GLN D 228 SER D 244 1 ? 17 
HELX_P HELX_P51 AF6 LEU D 79  ? GLU D 99  ? LEU D 249 GLU D 269 1 ? 21 
HELX_P HELX_P52 AF7 GLU D 104 ? ILE D 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P53 AF8 THR D 117 ? LEU D 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P54 AF9 THR D 140 ? PHE D 149 ? THR D 310 PHE D 319 1 ? 10 
HELX_P HELX_P55 AG1 LEU D 150 ? GLN D 152 ? LEU D 320 GLN D 322 5 ? 3  
HELX_P HELX_P56 AG2 ASN D 156 ? ASP D 173 ? ASN D 326 ASP D 343 1 ? 18 
HELX_P HELX_P57 AG3 ASP D 173 ? LEU D 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P58 AG4 LEU D 181 ? THR D 198 ? LEU D 351 THR D 368 1 ? 18 
HELX_P HELX_P59 AG5 PRO D 203 ? GLY D 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P60 AG6 LEU D 217 ? ALA D 231 ? LEU D 387 ALA D 401 1 ? 15 
HELX_P HELX_P61 AG7 PRO D 232 ? HIS D 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P62 AG8 GLN D 237 ? TYR D 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P63 AG9 LYS D 244 ? HIS D 249 ? LYS D 414 HIS D 419 5 ? 6  
HELX_P HELX_P64 AH1 GLY D 250 ? LEU D 254 ? GLY D 420 LEU D 424 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A TYR 163 C ? ? ? 1_555 A TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.325 ? ? 
covale2 covale both ? A TPO 164 C ? ? ? 1_555 A HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.345 ? ? 
covale3 covale both ? C TYR 163 C ? ? ? 1_555 C TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.351 ? ? 
covale4 covale both ? C TPO 164 C ? ? ? 1_555 C HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.342 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO A 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO C 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 158 A . ? VAL 154 A PRO 159 A ? PRO 155 A 1 -9.49 
2 GLN 153 B . ? GLN 323 B PRO 154 B ? PRO 324 B 1 -7.46 
3 ASP 175 B . ? ASP 345 B PRO 176 B ? PRO 346 B 1 5.30  
4 VAL 158 C . ? VAL 154 C PRO 159 C ? PRO 155 C 1 0.85  
5 GLN 153 D . ? GLN 323 D PRO 154 D ? PRO 324 D 1 4.13  
6 ASP 175 D . ? ASP 345 D PRO 176 D ? PRO 346 D 1 7.23  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 8   ? GLU A 16  ? PHE A 4   GLU A 12  
AA1 2 VAL A 21  ? ASN A 27  ? VAL A 17  ASN A 23  
AA1 3 VAL A 33  ? ARG A 40  ? VAL A 29  ARG A 36  
AA1 4 LYS A 79  ? GLU A 85  ? LYS A 75  GLU A 81  
AA1 5 LEU A 70  ? HIS A 75  ? LEU A 66  HIS A 71  
AA2 1 GLN A 89  ? ASP A 90  ? GLN A 85  ASP A 86  
AA2 2 LEU A 137 ? ILE A 139 ? LEU A 133 ILE A 135 
AA2 3 ILE A 145 ? LEU A 147 ? ILE A 141 LEU A 143 
AA3 1 VAL A 127 ? LEU A 128 ? VAL A 123 LEU A 124 
AA3 2 ARG A 154 ? ALA A 155 ? ARG A 150 ALA A 151 
AA4 1 PHE C 8   ? GLU C 16  ? PHE C 4   GLU C 12  
AA4 2 GLY C 20  ? ASN C 27  ? GLY C 16  ASN C 23  
AA4 3 VAL C 33  ? ARG C 40  ? VAL C 29  ARG C 36  
AA4 4 LYS C 79  ? GLU C 85  ? LYS C 75  GLU C 81  
AA4 5 LEU C 70  ? HIS C 75  ? LEU C 66  HIS C 71  
AA5 1 GLN C 89  ? ASP C 90  ? GLN C 85  ASP C 86  
AA5 2 LEU C 137 ? ILE C 139 ? LEU C 133 ILE C 135 
AA5 3 ILE C 145 ? LEU C 147 ? ILE C 141 LEU C 143 
AA6 1 VAL C 127 ? LEU C 128 ? VAL C 123 LEU C 124 
AA6 2 ARG C 154 ? ALA C 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 14  ? N ILE A 10  O VAL A 22  ? O VAL A 18  
AA1 2 3 N ALA A 25  ? N ALA A 21  O VAL A 34  ? O VAL A 30  
AA1 3 4 N ALA A 35  ? N ALA A 31  O PHE A 84  ? O PHE A 80  
AA1 4 5 O VAL A 83  ? O VAL A 79  N LEU A 71  ? N LEU A 67  
AA2 1 2 N GLN A 89  ? N GLN A 85  O ILE A 139 ? O ILE A 135 
AA2 2 3 N LEU A 138 ? N LEU A 134 O LYS A 146 ? O LYS A 142 
AA3 1 2 N LEU A 128 ? N LEU A 124 O ARG A 154 ? O ARG A 150 
AA4 1 2 N ILE C 14  ? N ILE C 10  O VAL C 22  ? O VAL C 18  
AA4 2 3 N ALA C 25  ? N ALA C 21  O VAL C 34  ? O VAL C 30  
AA4 3 4 N ILE C 39  ? N ILE C 35  O LEU C 80  ? O LEU C 76  
AA4 4 5 O VAL C 83  ? O VAL C 79  N LEU C 71  ? N LEU C 67  
AA5 1 2 N GLN C 89  ? N GLN C 85  O ILE C 139 ? O ILE C 135 
AA5 2 3 N LEU C 138 ? N LEU C 134 O LYS C 146 ? O LYS C 142 
AA6 1 2 N LEU C 128 ? N LEU C 124 O ARG C 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ET1 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 95  ? ? -105.29 76.50   
2  1 ARG A 126 ? ? 87.90   15.93   
3  1 ASP A 127 ? ? -164.19 43.70   
4  1 ASP A 145 ? ? 58.27   87.59   
5  1 VAL A 164 ? ? 77.58   126.34  
6  1 SER A 181 ? ? -144.76 -156.63 
7  1 ASP A 223 ? ? -126.95 -169.78 
8  1 THR A 290 ? ? -140.01 -10.29  
9  1 VAL B 175 ? ? 33.49   62.97   
10 1 TRP B 372 ? ? -35.04  117.52  
11 1 THR C 41  ? ? -123.61 -80.21  
12 1 ASP C 127 ? ? -146.48 41.62   
13 1 ASP C 145 ? ? 51.33   83.18   
14 1 VAL C 164 ? ? 76.93   124.91  
15 1 TRP D 372 ? ? -35.55  110.84  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 36  ? ? 0.170 'SIDE CHAIN' 
2 1 ARG A 150 ? ? 0.253 'SIDE CHAIN' 
3 1 ARG A 157 ? ? 0.088 'SIDE CHAIN' 
4 1 ARG B 187 ? ? 0.140 'SIDE CHAIN' 
5 1 ARG C 36  ? ? 0.138 'SIDE CHAIN' 
6 1 ARG C 200 ? ? 0.131 'SIDE CHAIN' 
7 1 ARG D 250 ? ? 0.223 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 A TPO 164 A TPO 160 ? THR 'modified residue' 
2 C TPO 164 C TPO 160 ? THR 'modified residue' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       602 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   5.82 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 B HIS 433 ? B HIS 263 
2  1 Y 1 B HIS 434 ? B HIS 264 
3  1 Y 1 B HIS 435 ? B HIS 265 
4  1 Y 1 B HIS 436 ? B HIS 266 
5  1 Y 1 B HIS 437 ? B HIS 267 
6  1 Y 1 B HIS 438 ? B HIS 268 
7  1 Y 1 C GLY -3  ? C GLY 1   
8  1 Y 1 C PRO -2  ? C PRO 2   
9  1 Y 1 C GLY -1  ? C GLY 3   
10 1 Y 1 C ARG 297 ? C ARG 301 
11 1 Y 1 C LEU 298 ? C LEU 302 
12 1 Y 1 D HIS 433 ? D HIS 263 
13 1 Y 1 D HIS 434 ? D HIS 264 
14 1 Y 1 D HIS 435 ? D HIS 265 
15 1 Y 1 D HIS 436 ? D HIS 266 
16 1 Y 1 D HIS 437 ? D HIS 267 
17 1 Y 1 D HIS 438 ? D HIS 268 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
IJL C4   C Y N 161 
IJL C5   C Y N 162 
IJL C6   C Y N 163 
IJL C7   C Y N 164 
IJL N1   N N N 165 
IJL C3   C Y N 166 
IJL C1   C N N 167 
IJL O1   O N N 168 
IJL C2   C Y N 169 
IJL I1   I N N 170 
IJL H1   H N N 171 
IJL H2   H N N 172 
IJL H3   H N N 173 
IJL H4   H N N 174 
IJL H5   H N N 175 
IJL H6   H N N 176 
ILE N    N N N 177 
ILE CA   C N S 178 
ILE C    C N N 179 
ILE O    O N N 180 
ILE CB   C N S 181 
ILE CG1  C N N 182 
ILE CG2  C N N 183 
ILE CD1  C N N 184 
ILE OXT  O N N 185 
ILE H    H N N 186 
ILE H2   H N N 187 
ILE HA   H N N 188 
ILE HB   H N N 189 
ILE HG12 H N N 190 
ILE HG13 H N N 191 
ILE HG21 H N N 192 
ILE HG22 H N N 193 
ILE HG23 H N N 194 
ILE HD11 H N N 195 
ILE HD12 H N N 196 
ILE HD13 H N N 197 
ILE HXT  H N N 198 
LEU N    N N N 199 
LEU CA   C N S 200 
LEU C    C N N 201 
LEU O    O N N 202 
LEU CB   C N N 203 
LEU CG   C N N 204 
LEU CD1  C N N 205 
LEU CD2  C N N 206 
LEU OXT  O N N 207 
LEU H    H N N 208 
LEU H2   H N N 209 
LEU HA   H N N 210 
LEU HB2  H N N 211 
LEU HB3  H N N 212 
LEU HG   H N N 213 
LEU HD11 H N N 214 
LEU HD12 H N N 215 
LEU HD13 H N N 216 
LEU HD21 H N N 217 
LEU HD22 H N N 218 
LEU HD23 H N N 219 
LEU HXT  H N N 220 
LYS N    N N N 221 
LYS CA   C N S 222 
LYS C    C N N 223 
LYS O    O N N 224 
LYS CB   C N N 225 
LYS CG   C N N 226 
LYS CD   C N N 227 
LYS CE   C N N 228 
LYS NZ   N N N 229 
LYS OXT  O N N 230 
LYS H    H N N 231 
LYS H2   H N N 232 
LYS HA   H N N 233 
LYS HB2  H N N 234 
LYS HB3  H N N 235 
LYS HG2  H N N 236 
LYS HG3  H N N 237 
LYS HD2  H N N 238 
LYS HD3  H N N 239 
LYS HE2  H N N 240 
LYS HE3  H N N 241 
LYS HZ1  H N N 242 
LYS HZ2  H N N 243 
LYS HZ3  H N N 244 
LYS HXT  H N N 245 
MET N    N N N 246 
MET CA   C N S 247 
MET C    C N N 248 
MET O    O N N 249 
MET CB   C N N 250 
MET CG   C N N 251 
MET SD   S N N 252 
MET CE   C N N 253 
MET OXT  O N N 254 
MET H    H N N 255 
MET H2   H N N 256 
MET HA   H N N 257 
MET HB2  H N N 258 
MET HB3  H N N 259 
MET HG2  H N N 260 
MET HG3  H N N 261 
MET HE1  H N N 262 
MET HE2  H N N 263 
MET HE3  H N N 264 
MET HXT  H N N 265 
PHE N    N N N 266 
PHE CA   C N S 267 
PHE C    C N N 268 
PHE O    O N N 269 
PHE CB   C N N 270 
PHE CG   C Y N 271 
PHE CD1  C Y N 272 
PHE CD2  C Y N 273 
PHE CE1  C Y N 274 
PHE CE2  C Y N 275 
PHE CZ   C Y N 276 
PHE OXT  O N N 277 
PHE H    H N N 278 
PHE H2   H N N 279 
PHE HA   H N N 280 
PHE HB2  H N N 281 
PHE HB3  H N N 282 
PHE HD1  H N N 283 
PHE HD2  H N N 284 
PHE HE1  H N N 285 
PHE HE2  H N N 286 
PHE HZ   H N N 287 
PHE HXT  H N N 288 
PRO N    N N N 289 
PRO CA   C N S 290 
PRO C    C N N 291 
PRO O    O N N 292 
PRO CB   C N N 293 
PRO CG   C N N 294 
PRO CD   C N N 295 
PRO OXT  O N N 296 
PRO H    H N N 297 
PRO HA   H N N 298 
PRO HB2  H N N 299 
PRO HB3  H N N 300 
PRO HG2  H N N 301 
PRO HG3  H N N 302 
PRO HD2  H N N 303 
PRO HD3  H N N 304 
PRO HXT  H N N 305 
SER N    N N N 306 
SER CA   C N S 307 
SER C    C N N 308 
SER O    O N N 309 
SER CB   C N N 310 
SER OG   O N N 311 
SER OXT  O N N 312 
SER H    H N N 313 
SER H2   H N N 314 
SER HA   H N N 315 
SER HB2  H N N 316 
SER HB3  H N N 317 
SER HG   H N N 318 
SER HXT  H N N 319 
THR N    N N N 320 
THR CA   C N S 321 
THR C    C N N 322 
THR O    O N N 323 
THR CB   C N R 324 
THR OG1  O N N 325 
THR CG2  C N N 326 
THR OXT  O N N 327 
THR H    H N N 328 
THR H2   H N N 329 
THR HA   H N N 330 
THR HB   H N N 331 
THR HG1  H N N 332 
THR HG21 H N N 333 
THR HG22 H N N 334 
THR HG23 H N N 335 
THR HXT  H N N 336 
TPO N    N N N 337 
TPO CA   C N S 338 
TPO CB   C N R 339 
TPO CG2  C N N 340 
TPO OG1  O N N 341 
TPO P    P N N 342 
TPO O1P  O N N 343 
TPO O2P  O N N 344 
TPO O3P  O N N 345 
TPO C    C N N 346 
TPO O    O N N 347 
TPO OXT  O N N 348 
TPO H    H N N 349 
TPO H2   H N N 350 
TPO HA   H N N 351 
TPO HB   H N N 352 
TPO HG21 H N N 353 
TPO HG22 H N N 354 
TPO HG23 H N N 355 
TPO HOP2 H N N 356 
TPO HOP3 H N N 357 
TPO HXT  H N N 358 
TRP N    N N N 359 
TRP CA   C N S 360 
TRP C    C N N 361 
TRP O    O N N 362 
TRP CB   C N N 363 
TRP CG   C Y N 364 
TRP CD1  C Y N 365 
TRP CD2  C Y N 366 
TRP NE1  N Y N 367 
TRP CE2  C Y N 368 
TRP CE3  C Y N 369 
TRP CZ2  C Y N 370 
TRP CZ3  C Y N 371 
TRP CH2  C Y N 372 
TRP OXT  O N N 373 
TRP H    H N N 374 
TRP H2   H N N 375 
TRP HA   H N N 376 
TRP HB2  H N N 377 
TRP HB3  H N N 378 
TRP HD1  H N N 379 
TRP HE1  H N N 380 
TRP HE3  H N N 381 
TRP HZ2  H N N 382 
TRP HZ3  H N N 383 
TRP HH2  H N N 384 
TRP HXT  H N N 385 
TYR N    N N N 386 
TYR CA   C N S 387 
TYR C    C N N 388 
TYR O    O N N 389 
TYR CB   C N N 390 
TYR CG   C Y N 391 
TYR CD1  C Y N 392 
TYR CD2  C Y N 393 
TYR CE1  C Y N 394 
TYR CE2  C Y N 395 
TYR CZ   C Y N 396 
TYR OH   O N N 397 
TYR OXT  O N N 398 
TYR H    H N N 399 
TYR H2   H N N 400 
TYR HA   H N N 401 
TYR HB2  H N N 402 
TYR HB3  H N N 403 
TYR HD1  H N N 404 
TYR HD2  H N N 405 
TYR HE1  H N N 406 
TYR HE2  H N N 407 
TYR HH   H N N 408 
TYR HXT  H N N 409 
VAL N    N N N 410 
VAL CA   C N S 411 
VAL C    C N N 412 
VAL O    O N N 413 
VAL CB   C N N 414 
VAL CG1  C N N 415 
VAL CG2  C N N 416 
VAL OXT  O N N 417 
VAL H    H N N 418 
VAL H2   H N N 419 
VAL HA   H N N 420 
VAL HB   H N N 421 
VAL HG11 H N N 422 
VAL HG12 H N N 423 
VAL HG13 H N N 424 
VAL HG21 H N N 425 
VAL HG22 H N N 426 
VAL HG23 H N N 427 
VAL HXT  H N N 428 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
IJL I1  C5   sing N N 152 
IJL C4  C5   doub Y N 153 
IJL C4  C3   sing Y N 154 
IJL C5  C6   sing Y N 155 
IJL C3  C2   doub Y N 156 
IJL C6  C7   doub Y N 157 
IJL C2  C7   sing Y N 158 
IJL C2  C1   sing N N 159 
IJL N1  C1   sing N N 160 
IJL C1  O1   doub N N 161 
IJL C4  H1   sing N N 162 
IJL C6  H2   sing N N 163 
IJL C7  H3   sing N N 164 
IJL N1  H4   sing N N 165 
IJL N1  H5   sing N N 166 
IJL C3  H6   sing N N 167 
ILE N   CA   sing N N 168 
ILE N   H    sing N N 169 
ILE N   H2   sing N N 170 
ILE CA  C    sing N N 171 
ILE CA  CB   sing N N 172 
ILE CA  HA   sing N N 173 
ILE C   O    doub N N 174 
ILE C   OXT  sing N N 175 
ILE CB  CG1  sing N N 176 
ILE CB  CG2  sing N N 177 
ILE CB  HB   sing N N 178 
ILE CG1 CD1  sing N N 179 
ILE CG1 HG12 sing N N 180 
ILE CG1 HG13 sing N N 181 
ILE CG2 HG21 sing N N 182 
ILE CG2 HG22 sing N N 183 
ILE CG2 HG23 sing N N 184 
ILE CD1 HD11 sing N N 185 
ILE CD1 HD12 sing N N 186 
ILE CD1 HD13 sing N N 187 
ILE OXT HXT  sing N N 188 
LEU N   CA   sing N N 189 
LEU N   H    sing N N 190 
LEU N   H2   sing N N 191 
LEU CA  C    sing N N 192 
LEU CA  CB   sing N N 193 
LEU CA  HA   sing N N 194 
LEU C   O    doub N N 195 
LEU C   OXT  sing N N 196 
LEU CB  CG   sing N N 197 
LEU CB  HB2  sing N N 198 
LEU CB  HB3  sing N N 199 
LEU CG  CD1  sing N N 200 
LEU CG  CD2  sing N N 201 
LEU CG  HG   sing N N 202 
LEU CD1 HD11 sing N N 203 
LEU CD1 HD12 sing N N 204 
LEU CD1 HD13 sing N N 205 
LEU CD2 HD21 sing N N 206 
LEU CD2 HD22 sing N N 207 
LEU CD2 HD23 sing N N 208 
LEU OXT HXT  sing N N 209 
LYS N   CA   sing N N 210 
LYS N   H    sing N N 211 
LYS N   H2   sing N N 212 
LYS CA  C    sing N N 213 
LYS CA  CB   sing N N 214 
LYS CA  HA   sing N N 215 
LYS C   O    doub N N 216 
LYS C   OXT  sing N N 217 
LYS CB  CG   sing N N 218 
LYS CB  HB2  sing N N 219 
LYS CB  HB3  sing N N 220 
LYS CG  CD   sing N N 221 
LYS CG  HG2  sing N N 222 
LYS CG  HG3  sing N N 223 
LYS CD  CE   sing N N 224 
LYS CD  HD2  sing N N 225 
LYS CD  HD3  sing N N 226 
LYS CE  NZ   sing N N 227 
LYS CE  HE2  sing N N 228 
LYS CE  HE3  sing N N 229 
LYS NZ  HZ1  sing N N 230 
LYS NZ  HZ2  sing N N 231 
LYS NZ  HZ3  sing N N 232 
LYS OXT HXT  sing N N 233 
MET N   CA   sing N N 234 
MET N   H    sing N N 235 
MET N   H2   sing N N 236 
MET CA  C    sing N N 237 
MET CA  CB   sing N N 238 
MET CA  HA   sing N N 239 
MET C   O    doub N N 240 
MET C   OXT  sing N N 241 
MET CB  CG   sing N N 242 
MET CB  HB2  sing N N 243 
MET CB  HB3  sing N N 244 
MET CG  SD   sing N N 245 
MET CG  HG2  sing N N 246 
MET CG  HG3  sing N N 247 
MET SD  CE   sing N N 248 
MET CE  HE1  sing N N 249 
MET CE  HE2  sing N N 250 
MET CE  HE3  sing N N 251 
MET OXT HXT  sing N N 252 
PHE N   CA   sing N N 253 
PHE N   H    sing N N 254 
PHE N   H2   sing N N 255 
PHE CA  C    sing N N 256 
PHE CA  CB   sing N N 257 
PHE CA  HA   sing N N 258 
PHE C   O    doub N N 259 
PHE C   OXT  sing N N 260 
PHE CB  CG   sing N N 261 
PHE CB  HB2  sing N N 262 
PHE CB  HB3  sing N N 263 
PHE CG  CD1  doub Y N 264 
PHE CG  CD2  sing Y N 265 
PHE CD1 CE1  sing Y N 266 
PHE CD1 HD1  sing N N 267 
PHE CD2 CE2  doub Y N 268 
PHE CD2 HD2  sing N N 269 
PHE CE1 CZ   doub Y N 270 
PHE CE1 HE1  sing N N 271 
PHE CE2 CZ   sing Y N 272 
PHE CE2 HE2  sing N N 273 
PHE CZ  HZ   sing N N 274 
PHE OXT HXT  sing N N 275 
PRO N   CA   sing N N 276 
PRO N   CD   sing N N 277 
PRO N   H    sing N N 278 
PRO CA  C    sing N N 279 
PRO CA  CB   sing N N 280 
PRO CA  HA   sing N N 281 
PRO C   O    doub N N 282 
PRO C   OXT  sing N N 283 
PRO CB  CG   sing N N 284 
PRO CB  HB2  sing N N 285 
PRO CB  HB3  sing N N 286 
PRO CG  CD   sing N N 287 
PRO CG  HG2  sing N N 288 
PRO CG  HG3  sing N N 289 
PRO CD  HD2  sing N N 290 
PRO CD  HD3  sing N N 291 
PRO OXT HXT  sing N N 292 
SER N   CA   sing N N 293 
SER N   H    sing N N 294 
SER N   H2   sing N N 295 
SER CA  C    sing N N 296 
SER CA  CB   sing N N 297 
SER CA  HA   sing N N 298 
SER C   O    doub N N 299 
SER C   OXT  sing N N 300 
SER CB  OG   sing N N 301 
SER CB  HB2  sing N N 302 
SER CB  HB3  sing N N 303 
SER OG  HG   sing N N 304 
SER OXT HXT  sing N N 305 
THR N   CA   sing N N 306 
THR N   H    sing N N 307 
THR N   H2   sing N N 308 
THR CA  C    sing N N 309 
THR CA  CB   sing N N 310 
THR CA  HA   sing N N 311 
THR C   O    doub N N 312 
THR C   OXT  sing N N 313 
THR CB  OG1  sing N N 314 
THR CB  CG2  sing N N 315 
THR CB  HB   sing N N 316 
THR OG1 HG1  sing N N 317 
THR CG2 HG21 sing N N 318 
THR CG2 HG22 sing N N 319 
THR CG2 HG23 sing N N 320 
THR OXT HXT  sing N N 321 
TPO N   CA   sing N N 322 
TPO N   H    sing N N 323 
TPO N   H2   sing N N 324 
TPO CA  CB   sing N N 325 
TPO CA  C    sing N N 326 
TPO CA  HA   sing N N 327 
TPO CB  CG2  sing N N 328 
TPO CB  OG1  sing N N 329 
TPO CB  HB   sing N N 330 
TPO CG2 HG21 sing N N 331 
TPO CG2 HG22 sing N N 332 
TPO CG2 HG23 sing N N 333 
TPO OG1 P    sing N N 334 
TPO P   O1P  doub N N 335 
TPO P   O2P  sing N N 336 
TPO P   O3P  sing N N 337 
TPO O2P HOP2 sing N N 338 
TPO O3P HOP3 sing N N 339 
TPO C   O    doub N N 340 
TPO C   OXT  sing N N 341 
TPO OXT HXT  sing N N 342 
TRP N   CA   sing N N 343 
TRP N   H    sing N N 344 
TRP N   H2   sing N N 345 
TRP CA  C    sing N N 346 
TRP CA  CB   sing N N 347 
TRP CA  HA   sing N N 348 
TRP C   O    doub N N 349 
TRP C   OXT  sing N N 350 
TRP CB  CG   sing N N 351 
TRP CB  HB2  sing N N 352 
TRP CB  HB3  sing N N 353 
TRP CG  CD1  doub Y N 354 
TRP CG  CD2  sing Y N 355 
TRP CD1 NE1  sing Y N 356 
TRP CD1 HD1  sing N N 357 
TRP CD2 CE2  doub Y N 358 
TRP CD2 CE3  sing Y N 359 
TRP NE1 CE2  sing Y N 360 
TRP NE1 HE1  sing N N 361 
TRP CE2 CZ2  sing Y N 362 
TRP CE3 CZ3  doub Y N 363 
TRP CE3 HE3  sing N N 364 
TRP CZ2 CH2  doub Y N 365 
TRP CZ2 HZ2  sing N N 366 
TRP CZ3 CH2  sing Y N 367 
TRP CZ3 HZ3  sing N N 368 
TRP CH2 HH2  sing N N 369 
TRP OXT HXT  sing N N 370 
TYR N   CA   sing N N 371 
TYR N   H    sing N N 372 
TYR N   H2   sing N N 373 
TYR CA  C    sing N N 374 
TYR CA  CB   sing N N 375 
TYR CA  HA   sing N N 376 
TYR C   O    doub N N 377 
TYR C   OXT  sing N N 378 
TYR CB  CG   sing N N 379 
TYR CB  HB2  sing N N 380 
TYR CB  HB3  sing N N 381 
TYR CG  CD1  doub Y N 382 
TYR CG  CD2  sing Y N 383 
TYR CD1 CE1  sing Y N 384 
TYR CD1 HD1  sing N N 385 
TYR CD2 CE2  doub Y N 386 
TYR CD2 HD2  sing N N 387 
TYR CE1 CZ   doub Y N 388 
TYR CE1 HE1  sing N N 389 
TYR CE2 CZ   sing Y N 390 
TYR CE2 HE2  sing N N 391 
TYR CZ  OH   sing N N 392 
TYR OH  HH   sing N N 393 
TYR OXT HXT  sing N N 394 
VAL N   CA   sing N N 395 
VAL N   H    sing N N 396 
VAL N   H2   sing N N 397 
VAL CA  C    sing N N 398 
VAL CA  CB   sing N N 399 
VAL CA  HA   sing N N 400 
VAL C   O    doub N N 401 
VAL C   OXT  sing N N 402 
VAL CB  CG1  sing N N 403 
VAL CB  CG2  sing N N 404 
VAL CB  HB   sing N N 405 
VAL CG1 HG11 sing N N 406 
VAL CG1 HG12 sing N N 407 
VAL CG1 HG13 sing N N 408 
VAL CG2 HG21 sing N N 409 
VAL CG2 HG22 sing N N 410 
VAL CG2 HG23 sing N N 411 
VAL OXT HXT  sing N N 412 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ET1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013519 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007503 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006791 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201  10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
I 53 53 20.1470 4.3470  18.9947 0.3814  7.5137 27.7660 2.2735 66.8776 3.6514   
N 7  7  12.2220 0.0057  3.1346  9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870  5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P 15 15 6.4348  1.9067  4.1793  27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S 16 16 6.9054  1.4679  5.2035  22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 1   ? -22.536 -7.316  23.958  1   64.59  ? -3  GLY A N   1 
ATOM   2    C CA  . GLY A 1 1   ? -21.282 -7.5    24.713  1   62.07  ? -3  GLY A CA  1 
ATOM   3    C C   . GLY A 1 1   ? -21.484 -7.248  26.205  1   63.05  ? -3  GLY A C   1 
ATOM   4    O O   . GLY A 1 1   ? -20.826 -6.373  26.758  1   64.55  ? -3  GLY A O   1 
ATOM   5    N N   . PRO A 1 2   ? -22.339 -8.038  26.91   1   66.4   ? -2  PRO A N   1 
ATOM   6    C CA  . PRO A 1 2   ? -22.664 -7.77   28.318  1   72.76  ? -2  PRO A CA  1 
ATOM   7    C C   . PRO A 1 2   ? -21.61  -8.09   29.387  1   65.52  ? -2  PRO A C   1 
ATOM   8    O O   . PRO A 1 2   ? -21.87  -7.918  30.574  1   68.08  ? -2  PRO A O   1 
ATOM   9    C CB  . PRO A 1 2   ? -23.946 -8.629  28.486  1   76.25  ? -2  PRO A CB  1 
ATOM   10   C CG  . PRO A 1 2   ? -23.685 -9.854  27.63   1   65.49  ? -2  PRO A CG  1 
ATOM   11   C CD  . PRO A 1 2   ? -22.984 -9.272  26.413  1   59.98  ? -2  PRO A CD  1 
ATOM   12   N N   . GLY A 1 3   ? -20.423 -8.544  28.962  1   59.31  ? -1  GLY A N   1 
ATOM   13   C CA  . GLY A 1 3   ? -19.346 -8.938  29.866  1   55.19  ? -1  GLY A CA  1 
ATOM   14   C C   . GLY A 1 3   ? -18.599 -7.757  30.497  1   49.98  ? -1  GLY A C   1 
ATOM   15   O O   . GLY A 1 3   ? -18.567 -6.649  29.969  1   46     ? -1  GLY A O   1 
ATOM   16   N N   . SER A 1 4   ? -18.004 -8.018  31.664  1   57.06  ? 0   SER A N   1 
ATOM   17   C CA  . SER A 1 4   ? -17.162 -7.086  32.409  1   58.24  ? 0   SER A CA  1 
ATOM   18   C C   . SER A 1 4   ? -16.024 -7.903  33.023  1   52.69  ? 0   SER A C   1 
ATOM   19   O O   . SER A 1 4   ? -16.255 -9.058  33.38   1   59.02  ? 0   SER A O   1 
ATOM   20   C CB  . SER A 1 4   ? -17.982 -6.398  33.476  1   58.43  ? 0   SER A CB  1 
ATOM   21   O OG  . SER A 1 4   ? -17.427 -5.144  33.843  1   67.11  ? 0   SER A OG  1 
ATOM   22   N N   . MET A 1 5   ? -14.809 -7.338  33.119  1   44.94  ? 1   MET A N   1 
ATOM   23   C CA  . MET A 1 5   ? -13.681 -8.119  33.618  1   37.72  ? 1   MET A CA  1 
ATOM   24   C C   . MET A 1 5   ? -13.839 -8.41   35.103  1   34.11  ? 1   MET A C   1 
ATOM   25   O O   . MET A 1 5   ? -13.318 -9.4    35.598  1   36.95  ? 1   MET A O   1 
ATOM   26   C CB  . MET A 1 5   ? -12.331 -7.47   33.323  1   32.83  ? 1   MET A CB  1 
ATOM   27   C CG  . MET A 1 5   ? -12.055 -7.436  31.847  1   38.41  ? 1   MET A CG  1 
ATOM   28   S SD  . MET A 1 5   ? -12.516 -8.953  30.984  1   45.07  ? 1   MET A SD  1 
ATOM   29   C CE  . MET A 1 5   ? -11.085 -9.961  31.394  1   38.02  ? 1   MET A CE  1 
ATOM   30   N N   . GLU A 1 6   ? -14.608 -7.57   35.788  1   35.03  ? 2   GLU A N   1 
ATOM   31   C CA  . GLU A 1 6   ? -14.867 -7.755  37.204  1   38.74  ? 2   GLU A CA  1 
ATOM   32   C C   . GLU A 1 6   ? -15.513 -9.122  37.463  1   34.11  ? 2   GLU A C   1 
ATOM   33   O O   . GLU A 1 6   ? -15.384 -9.652  38.564  1   34.46  ? 2   GLU A O   1 
ATOM   34   C CB  . GLU A 1 6   ? -15.628 -6.532  37.73   1   47.81  ? 2   GLU A CB  1 
ATOM   35   C CG  . GLU A 1 6   ? -15.684 -6.439  39.256  1   61.4   ? 2   GLU A CG  1 
ATOM   36   C CD  . GLU A 1 6   ? -17.014 -6.668  39.975  1   76.2   ? 2   GLU A CD  1 
ATOM   37   O OE1 . GLU A 1 6   ? -16.944 -6.992  41.183  1   83.14  ? 2   GLU A OE1 1 
ATOM   38   O OE2 . GLU A 1 6   ? -18.114 -6.478  39.389  1   79.9   ? 2   GLU A OE2 1 
ATOM   39   N N   . ASN A 1 7   ? -16.17  -9.703  36.446  1   28.38  ? 3   ASN A N   1 
ATOM   40   C CA  . ASN A 1 7   ? -16.929 -10.938 36.603  1   25.57  ? 3   ASN A CA  1 
ATOM   41   C C   . ASN A 1 7   ? -16.086 -12.18  36.319  1   23.38  ? 3   ASN A C   1 
ATOM   42   O O   . ASN A 1 7   ? -16.568 -13.299 36.509  1   21.37  ? 3   ASN A O   1 
ATOM   43   C CB  . ASN A 1 7   ? -18.152 -10.994 35.689  1   29.07  ? 3   ASN A CB  1 
ATOM   44   C CG  . ASN A 1 7   ? -19.318 -10.159 36.166  1   33.48  ? 3   ASN A CG  1 
ATOM   45   O OD1 . ASN A 1 7   ? -19.432 -9.829  37.359  1   30.42  ? 3   ASN A OD1 1 
ATOM   46   N ND2 . ASN A 1 7   ? -20.211 -9.84   35.236  1   39.85  ? 3   ASN A ND2 1 
ATOM   47   N N   . PHE A 1 8   ? -14.854 -12.004 35.816  1   21.88  ? 4   PHE A N   1 
ATOM   48   C CA  . PHE A 1 8   ? -13.996 -13.158 35.608  1   20.3   ? 4   PHE A CA  1 
ATOM   49   C C   . PHE A 1 8   ? -12.886 -13.198 36.652  1   21.36  ? 4   PHE A C   1 
ATOM   50   O O   . PHE A 1 8   ? -12.38  -12.167 37.088  1   23.11  ? 4   PHE A O   1 
ATOM   51   C CB  . PHE A 1 8   ? -13.468 -13.209 34.183  1   19.59  ? 4   PHE A CB  1 
ATOM   52   C CG  . PHE A 1 8   ? -14.534 -13.294 33.102  1   20.22  ? 4   PHE A CG  1 
ATOM   53   C CD1 . PHE A 1 8   ? -15.067 -14.522 32.722  1   19.43  ? 4   PHE A CD1 1 
ATOM   54   C CD2 . PHE A 1 8   ? -14.979 -12.149 32.432  1   20.62  ? 4   PHE A CD2 1 
ATOM   55   C CE1 . PHE A 1 8   ? -16.039 -14.6   31.722  1   19.3   ? 4   PHE A CE1 1 
ATOM   56   C CE2 . PHE A 1 8   ? -15.942 -12.242 31.431  1   19.79  ? 4   PHE A CE2 1 
ATOM   57   C CZ  . PHE A 1 8   ? -16.466 -13.465 31.069  1   17.99  ? 4   PHE A CZ  1 
ATOM   58   N N   . GLN A 1 9   ? -12.58  -14.419 37.096  1   23.22  ? 5   GLN A N   1 
ATOM   59   C CA  . GLN A 1 9   ? -11.383 -14.742 37.853  1   25.61  ? 5   GLN A CA  1 
ATOM   60   C C   . GLN A 1 9   ? -10.455 -15.555 36.958  1   25.4   ? 5   GLN A C   1 
ATOM   61   O O   . GLN A 1 9   ? -10.822 -16.646 36.544  1   26.5   ? 5   GLN A O   1 
ATOM   62   C CB  . GLN A 1 9   ? -11.758 -15.625 39.046  1   28.39  ? 5   GLN A CB  1 
ATOM   63   C CG  . GLN A 1 9   ? -10.583 -16.114 39.884  1   30.56  ? 5   GLN A CG  1 
ATOM   64   C CD  . GLN A 1 9   ? -9.847  -14.978 40.553  1   34.16  ? 5   GLN A CD  1 
ATOM   65   O OE1 . GLN A 1 9   ? -10.458 -14.033 41.07   1   38.08  ? 5   GLN A OE1 1 
ATOM   66   N NE2 . GLN A 1 9   ? -8.525  -15.049 40.528  1   35.44  ? 5   GLN A NE2 1 
ATOM   67   N N   . LYS A 1 10  ? -9.26   -15.019 36.667  1   25.9   ? 6   LYS A N   1 
ATOM   68   C CA  . LYS A 1 10  ? -8.243  -15.735 35.912  1   25.43  ? 6   LYS A CA  1 
ATOM   69   C C   . LYS A 1 10  ? -7.783  -16.938 36.725  1   22.9   ? 6   LYS A C   1 
ATOM   70   O O   . LYS A 1 10  ? -7.684  -16.841 37.944  1   20.11  ? 6   LYS A O   1 
ATOM   71   C CB  . LYS A 1 10  ? -7.045  -14.826 35.617  1   29.5   ? 6   LYS A CB  1 
ATOM   72   C CG  . LYS A 1 10  ? -7.315  -13.718 34.605  1   34.96  ? 6   LYS A CG  1 
ATOM   73   C CD  . LYS A 1 10  ? -6.053  -13.005 34.127  1   39.24  ? 6   LYS A CD  1 
ATOM   74   C CE  . LYS A 1 10  ? -6.216  -12.382 32.764  1   41.75  ? 6   LYS A CE  1 
ATOM   75   N NZ  . LYS A 1 10  ? -7.11   -11.224 32.827  1   43.13  ? 6   LYS A NZ  1 
ATOM   76   N N   . VAL A 1 11  ? -7.493  -18.049 36.028  1   24.21  ? 7   VAL A N   1 
ATOM   77   C CA  . VAL A 1 11  ? -7.175  -19.321 36.661  1   25.57  ? 7   VAL A CA  1 
ATOM   78   C C   . VAL A 1 11  ? -5.733  -19.711 36.341  1   26.63  ? 7   VAL A C   1 
ATOM   79   O O   . VAL A 1 11  ? -5.038  -20.128 37.25   1   27.11  ? 7   VAL A O   1 
ATOM   80   C CB  . VAL A 1 11  ? -8.181  -20.431 36.294  1   25.37  ? 7   VAL A CB  1 
ATOM   81   C CG1 . VAL A 1 11  ? -7.784  -21.811 36.791  1   23.98  ? 7   VAL A CG1 1 
ATOM   82   C CG2 . VAL A 1 11  ? -9.567  -20.099 36.811  1   26.18  ? 7   VAL A CG2 1 
ATOM   83   N N   . GLU A 1 12  ? -5.295  -19.573 35.079  1   27.53  ? 8   GLU A N   1 
ATOM   84   C CA  . GLU A 1 12  ? -3.911  -19.85  34.71   1   30.26  ? 8   GLU A CA  1 
ATOM   85   C C   . GLU A 1 12  ? -3.711  -19.488 33.243  1   31.1   ? 8   GLU A C   1 
ATOM   86   O O   . GLU A 1 12  ? -4.691  -19.414 32.506  1   27.73  ? 8   GLU A O   1 
ATOM   87   C CB  . GLU A 1 12  ? -3.584  -21.337 34.867  1   31.2   ? 8   GLU A CB  1 
ATOM   88   C CG  . GLU A 1 12  ? -4.498  -22.205 34.01   1   33.25  ? 8   GLU A CG  1 
ATOM   89   C CD  . GLU A 1 12  ? -4.415  -23.71  34.113  1   33.94  ? 8   GLU A CD  1 
ATOM   90   O OE1 . GLU A 1 12  ? -4.861  -24.191 35.168  1   35.31  ? 8   GLU A OE1 1 
ATOM   91   O OE2 . GLU A 1 12  ? -3.956  -24.385 33.158  1   34.14  ? 8   GLU A OE2 1 
ATOM   92   N N   . LYS A 1 13  ? -2.446  -19.274 32.836  1   31.21  ? 9   LYS A N   1 
ATOM   93   C CA  . LYS A 1 13  ? -2.111  -19.046 31.441  1   31.32  ? 9   LYS A CA  1 
ATOM   94   C C   . LYS A 1 13  ? -2.341  -20.355 30.693  1   31.31  ? 9   LYS A C   1 
ATOM   95   O O   . LYS A 1 13  ? -2.166  -21.416 31.285  1   33.76  ? 9   LYS A O   1 
ATOM   96   C CB  . LYS A 1 13  ? -0.674  -18.532 31.344  1   34.19  ? 9   LYS A CB  1 
ATOM   97   C CG  . LYS A 1 13  ? -0.325  -17.912 29.999  1   46.38  ? 9   LYS A CG  1 
ATOM   98   C CD  . LYS A 1 13  ? 1.091   -17.359 29.821  1   52.73  ? 9   LYS A CD  1 
ATOM   99   C CE  . LYS A 1 13  ? 1.307   -17.098 28.348  1   63.32  ? 9   LYS A CE  1 
ATOM   100  N NZ  . LYS A 1 13  ? 2.662   -16.704 27.948  1   72.3   ? 9   LYS A NZ  1 
ATOM   101  N N   . ILE A 1 14  ? -2.788  -20.288 29.431  1   27.57  ? 10  ILE A N   1 
ATOM   102  C CA  . ILE A 1 14  ? -2.95   -21.521 28.68   1   27.91  ? 10  ILE A CA  1 
ATOM   103  C C   . ILE A 1 14  ? -2.28   -21.467 27.314  1   30.02  ? 10  ILE A C   1 
ATOM   104  O O   . ILE A 1 14  ? -2.158  -22.495 26.652  1   34.31  ? 10  ILE A O   1 
ATOM   105  C CB  . ILE A 1 14  ? -4.41   -21.985 28.568  1   28.1   ? 10  ILE A CB  1 
ATOM   106  C CG1 . ILE A 1 14  ? -5.34   -20.89  28.019  1   29.44  ? 10  ILE A CG1 1 
ATOM   107  C CG2 . ILE A 1 14  ? -4.865  -22.567 29.902  1   27.5   ? 10  ILE A CG2 1 
ATOM   108  C CD1 . ILE A 1 14  ? -6.798  -21.288 27.868  1   29.53  ? 10  ILE A CD1 1 
ATOM   109  N N   . GLY A 1 15  ? -1.842  -20.286 26.888  1   32.95  ? 11  GLY A N   1 
ATOM   110  C CA  . GLY A 1 15  ? -1.235  -20.21  25.571  1   43.1   ? 11  GLY A CA  1 
ATOM   111  C C   . GLY A 1 15  ? -0.831  -18.787 25.223  1   49.54  ? 11  GLY A C   1 
ATOM   112  O O   . GLY A 1 15  ? -1.015  -17.875 26.021  1   51.51  ? 11  GLY A O   1 
ATOM   113  N N   . GLU A 1 16  ? -0.278  -18.602 24.026  1   57.37  ? 12  GLU A N   1 
ATOM   114  C CA  . GLU A 1 16  ? 0.094   -17.253 23.657  1   65.96  ? 12  GLU A CA  1 
ATOM   115  C C   . GLU A 1 16  ? 0.096   -17.131 22.138  1   79.41  ? 12  GLU A C   1 
ATOM   116  O O   . GLU A 1 16  ? 0.831   -17.855 21.476  1   73.9   ? 12  GLU A O   1 
ATOM   117  C CB  . GLU A 1 16  ? 1.405   -16.972 24.386  1   60.8   ? 12  GLU A CB  1 
ATOM   118  C CG  . GLU A 1 16  ? 1.973   -15.597 24.07   1   68.59  ? 12  GLU A CG  1 
ATOM   119  C CD  . GLU A 1 16  ? 3.196   -15.349 24.932  1   75.37  ? 12  GLU A CD  1 
ATOM   120  O OE1 . GLU A 1 16  ? 3.729   -16.352 25.459  1   73.68  ? 12  GLU A OE1 1 
ATOM   121  O OE2 . GLU A 1 16  ? 3.6     -14.174 25.101  1   79.78  ? 12  GLU A OE2 1 
ATOM   122  N N   . GLY A 1 17  ? -0.735  -16.203 21.626  1   95.62  ? 13  GLY A N   1 
ATOM   123  C CA  . GLY A 1 17  ? -0.826  -15.831 20.216  1   99.73  ? 13  GLY A CA  1 
ATOM   124  C C   . GLY A 1 17  ? 0.03    -14.599 19.897  1   105.52 ? 13  GLY A C   1 
ATOM   125  O O   . GLY A 1 17  ? 1.02    -14.338 20.585  1   92.53  ? 13  GLY A O   1 
ATOM   126  N N   . THR A 1 18  ? -0.39   -13.808 18.891  1   102.66 ? 14  THR A N   1 
ATOM   127  C CA  . THR A 1 18  ? 0.428   -12.741 18.306  1   100.33 ? 14  THR A CA  1 
ATOM   128  C C   . THR A 1 18  ? 0.326   -11.408 19.055  1   101.97 ? 14  THR A C   1 
ATOM   129  O O   . THR A 1 18  ? 1.328   -10.691 19.153  1   87.55  ? 14  THR A O   1 
ATOM   130  C CB  . THR A 1 18  ? 0.127   -12.525 16.82   1   113.23 ? 14  THR A CB  1 
ATOM   131  O OG1 . THR A 1 18  ? 1.152   -11.624 16.399  1   126.28 ? 14  THR A OG1 1 
ATOM   132  C CG2 . THR A 1 18  ? -1.276  -11.993 16.576  1   104.66 ? 14  THR A CG2 1 
ATOM   133  N N   . TYR A 1 19  ? -0.887  -11.074 19.492  1   108.29 ? 15  TYR A N   1 
ATOM   134  C CA  . TYR A 1 19  ? -1.1    -9.773  20.175  1   102.38 ? 15  TYR A CA  1 
ATOM   135  C C   . TYR A 1 19  ? -1.377  -10.038 21.64   1   85.87  ? 15  TYR A C   1 
ATOM   136  O O   . TYR A 1 19  ? -1.76   -9.09   22.362  1   71.82  ? 15  TYR A O   1 
ATOM   137  C CB  . TYR A 1 19  ? -2.213  -9.017  19.445  1   100.26 ? 15  TYR A CB  1 
ATOM   138  C CG  . TYR A 1 19  ? -1.777  -8.593  18.051  1   110.44 ? 15  TYR A CG  1 
ATOM   139  C CD1 . TYR A 1 19  ? -0.758  -7.666  17.875  1   104.32 ? 15  TYR A CD1 1 
ATOM   140  C CD2 . TYR A 1 19  ? -2.358  -9.142  16.916  1   114.63 ? 15  TYR A CD2 1 
ATOM   141  C CE1 . TYR A 1 19  ? -0.341  -7.285  16.611  1   98     ? 15  TYR A CE1 1 
ATOM   142  C CE2 . TYR A 1 19  ? -1.947  -8.77   15.648  1   103.97 ? 15  TYR A CE2 1 
ATOM   143  C CZ  . TYR A 1 19  ? -0.941  -7.835  15.494  1   94.01  ? 15  TYR A CZ  1 
ATOM   144  O OH  . TYR A 1 19  ? -0.539  -7.464  14.244  1   85.45  ? 15  TYR A OH  1 
ATOM   145  N N   . GLY A 1 20  ? -1.198  -11.288 22.083  1   70.44  ? 16  GLY A N   1 
ATOM   146  C CA  . GLY A 1 20  ? -1.355  -11.492 23.512  1   61.48  ? 16  GLY A CA  1 
ATOM   147  C C   . GLY A 1 20  ? -1.368  -12.936 23.994  1   55.17  ? 16  GLY A C   1 
ATOM   148  O O   . GLY A 1 20  ? -0.796  -13.838 23.394  1   52.34  ? 16  GLY A O   1 
ATOM   149  N N   . VAL A 1 21  ? -1.999  -13.099 25.156  1   52.22  ? 17  VAL A N   1 
ATOM   150  C CA  . VAL A 1 21  ? -1.947  -14.326 25.926  1   48.64  ? 17  VAL A CA  1 
ATOM   151  C C   . VAL A 1 21  ? -3.367  -14.818 26.161  1   42.01  ? 17  VAL A C   1 
ATOM   152  O O   . VAL A 1 21  ? -4.307  -14.036 26.112  1   46.16  ? 17  VAL A O   1 
ATOM   153  C CB  . VAL A 1 21  ? -1.181  -14.134 27.25   1   48.51  ? 17  VAL A CB  1 
ATOM   154  C CG1 . VAL A 1 21  ? 0.302   -13.959 26.957  1   63.67  ? 17  VAL A CG1 1 
ATOM   155  C CG2 . VAL A 1 21  ? -1.708  -12.982 28.103  1   42.55  ? 17  VAL A CG2 1 
ATOM   156  N N   . VAL A 1 22  ? -3.495  -16.123 26.399  1   33.91  ? 18  VAL A N   1 
ATOM   157  C CA  . VAL A 1 22  ? -4.781  -16.728 26.676  1   28.54  ? 18  VAL A CA  1 
ATOM   158  C C   . VAL A 1 22  ? -4.782  -17.3   28.096  1   27.27  ? 18  VAL A C   1 
ATOM   159  O O   . VAL A 1 22  ? -3.92   -18.084 28.481  1   28.56  ? 18  VAL A O   1 
ATOM   160  C CB  . VAL A 1 22  ? -5.066  -17.772 25.585  1   26.58  ? 18  VAL A CB  1 
ATOM   161  C CG1 . VAL A 1 22  ? -6.464  -18.363 25.673  1   26.74  ? 18  VAL A CG1 1 
ATOM   162  C CG2 . VAL A 1 22  ? -4.824  -17.189 24.201  1   26.89  ? 18  VAL A CG2 1 
ATOM   163  N N   . TYR A 1 23  ? -5.759  -16.868 28.887  1   26.31  ? 19  TYR A N   1 
ATOM   164  C CA  . TYR A 1 23  ? -5.994  -17.405 30.216  1   26.76  ? 19  TYR A CA  1 
ATOM   165  C C   . TYR A 1 23  ? -7.257  -18.265 30.202  1   26.87  ? 19  TYR A C   1 
ATOM   166  O O   . TYR A 1 23  ? -8.255  -17.955 29.549  1   25.37  ? 19  TYR A O   1 
ATOM   167  C CB  . TYR A 1 23  ? -6.179  -16.27  31.221  1   29.09  ? 19  TYR A CB  1 
ATOM   168  C CG  . TYR A 1 23  ? -4.955  -15.402 31.476  1   36.57  ? 19  TYR A CG  1 
ATOM   169  C CD1 . TYR A 1 23  ? -4.611  -14.36  30.619  1   40.32  ? 19  TYR A CD1 1 
ATOM   170  C CD2 . TYR A 1 23  ? -4.168  -15.6   32.608  1   39.41  ? 19  TYR A CD2 1 
ATOM   171  C CE1 . TYR A 1 23  ? -3.499  -13.567 30.866  1   45.41  ? 19  TYR A CE1 1 
ATOM   172  C CE2 . TYR A 1 23  ? -3.056  -14.819 32.866  1   45.61  ? 19  TYR A CE2 1 
ATOM   173  C CZ  . TYR A 1 23  ? -2.72   -13.796 31.994  1   51.87  ? 19  TYR A CZ  1 
ATOM   174  O OH  . TYR A 1 23  ? -1.619  -13.035 32.302  1   56.83  ? 19  TYR A OH  1 
ATOM   175  N N   . LYS A 1 24  ? -7.192  -19.382 30.918  1   25.8   ? 20  LYS A N   1 
ATOM   176  C CA  . LYS A 1 24  ? -8.402  -20.018 31.397  1   23.28  ? 20  LYS A CA  1 
ATOM   177  C C   . LYS A 1 24  ? -8.952  -19.163 32.536  1   24.24  ? 20  LYS A C   1 
ATOM   178  O O   . LYS A 1 24  ? -8.218  -18.768 33.451  1   22.74  ? 20  LYS A O   1 
ATOM   179  C CB  . LYS A 1 24  ? -8.072  -21.435 31.865  1   23.06  ? 20  LYS A CB  1 
ATOM   180  C CG  . LYS A 1 24  ? -9.233  -22.185 32.478  1   22.94  ? 20  LYS A CG  1 
ATOM   181  C CD  . LYS A 1 24  ? -8.737  -23.484 33.082  1   22.96  ? 20  LYS A CD  1 
ATOM   182  C CE  . LYS A 1 24  ? -9.857  -24.39  33.44   1   24.06  ? 20  LYS A CE  1 
ATOM   183  N NZ  . LYS A 1 24  ? -9.273  -25.678 33.826  1   26.27  ? 20  LYS A NZ  1 
ATOM   184  N N   . ALA A 1 25  ? -10.257 -18.874 32.464  1   24.14  ? 21  ALA A N   1 
ATOM   185  C CA  . ALA A 1 25  ? -10.916 -18.036 33.453  1   22.83  ? 21  ALA A CA  1 
ATOM   186  C C   . ALA A 1 25  ? -12.299 -18.607 33.796  1   23.25  ? 21  ALA A C   1 
ATOM   187  O O   . ALA A 1 25  ? -12.869 -19.417 33.04   1   22.02  ? 21  ALA A O   1 
ATOM   188  C CB  . ALA A 1 25  ? -10.993 -16.645 32.88   1   21.47  ? 21  ALA A CB  1 
ATOM   189  N N   . ARG A 1 26  ? -12.835 -18.152 34.933  1   21.65  ? 22  ARG A N   1 
ATOM   190  C CA  . ARG A 1 26  ? -14.106 -18.614 35.468  1   23.5   ? 22  ARG A CA  1 
ATOM   191  C C   . ARG A 1 26  ? -15.05  -17.416 35.619  1   21.5   ? 22  ARG A C   1 
ATOM   192  O O   . ARG A 1 26  ? -14.65  -16.385 36.156  1   17.8   ? 22  ARG A O   1 
ATOM   193  C CB  . ARG A 1 26  ? -13.879 -19.269 36.835  1   26.97  ? 22  ARG A CB  1 
ATOM   194  C CG  . ARG A 1 26  ? -15.062 -20.071 37.357  1   33.72  ? 22  ARG A CG  1 
ATOM   195  C CD  . ARG A 1 26  ? -14.834 -20.667 38.734  1   39.17  ? 22  ARG A CD  1 
ATOM   196  N NE  . ARG A 1 26  ? -14.873 -19.679 39.824  1   47.42  ? 22  ARG A NE  1 
ATOM   197  C CZ  . ARG A 1 26  ? -13.81  -19.253 40.52   1   46.74  ? 22  ARG A CZ  1 
ATOM   198  N NH1 . ARG A 1 26  ? -12.599 -19.697 40.225  1   46.4   ? 22  ARG A NH1 1 
ATOM   199  N NH2 . ARG A 1 26  ? -13.951 -18.388 41.518  1   41.93  ? 22  ARG A NH2 1 
ATOM   200  N N   . ASN A 1 27  ? -16.282 -17.548 35.091  1   19.75  ? 23  ASN A N   1 
ATOM   201  C CA  . ASN A 1 27  ? -17.306 -16.534 35.274  1   17.91  ? 23  ASN A CA  1 
ATOM   202  C C   . ASN A 1 27  ? -17.804 -16.633 36.715  1   18.92  ? 23  ASN A C   1 
ATOM   203  O O   . ASN A 1 27  ? -18.318 -17.659 37.145  1   19.78  ? 23  ASN A O   1 
ATOM   204  C CB  . ASN A 1 27  ? -18.4   -16.671 34.217  1   15.88  ? 23  ASN A CB  1 
ATOM   205  C CG  . ASN A 1 27  ? -19.499 -15.638 34.354  1   14.17  ? 23  ASN A CG  1 
ATOM   206  O OD1 . ASN A 1 27  ? -19.974 -15.357 35.461  1   13.42  ? 23  ASN A OD1 1 
ATOM   207  N ND2 . ASN A 1 27  ? -19.958 -15.085 33.246  1   12.47  ? 23  ASN A ND2 1 
ATOM   208  N N   . LYS A 1 28  ? -17.664 -15.556 37.48   1   20.12  ? 24  LYS A N   1 
ATOM   209  C CA  . LYS A 1 28  ? -17.854 -15.678 38.911  1   19.3   ? 24  LYS A CA  1 
ATOM   210  C C   . LYS A 1 28  ? -19.336 -15.805 39.229  1   17.37  ? 24  LYS A C   1 
ATOM   211  O O   . LYS A 1 28  ? -19.687 -16.205 40.323  1   16.62  ? 24  LYS A O   1 
ATOM   212  C CB  . LYS A 1 28  ? -17.182 -14.508 39.633  1   23.31  ? 24  LYS A CB  1 
ATOM   213  C CG  . LYS A 1 28  ? -15.712 -14.772 39.963  1   30.03  ? 24  LYS A CG  1 
ATOM   214  C CD  . LYS A 1 28  ? -15.085 -13.713 40.88   1   35.7   ? 24  LYS A CD  1 
ATOM   215  C CE  . LYS A 1 28  ? -14.548 -12.535 40.097  1   39.32  ? 24  LYS A CE  1 
ATOM   216  N NZ  . LYS A 1 28  ? -13.795 -11.613 40.954  1   41.62  ? 24  LYS A NZ  1 
ATOM   217  N N   . LEU A 1 29  ? -20.203 -15.478 38.264  1   16.9   ? 25  LEU A N   1 
ATOM   218  C CA  . LEU A 1 29  ? -21.635 -15.406 38.516  1   15.96  ? 25  LEU A CA  1 
ATOM   219  C C   . LEU A 1 29  ? -22.353 -16.637 37.956  1   16.7   ? 25  LEU A C   1 
ATOM   220  O O   . LEU A 1 29  ? -23.26  -17.152 38.606  1   18.07  ? 25  LEU A O   1 
ATOM   221  C CB  . LEU A 1 29  ? -22.201 -14.094 37.978  1   14.38  ? 25  LEU A CB  1 
ATOM   222  C CG  . LEU A 1 29  ? -21.83  -12.832 38.762  1   13.6   ? 25  LEU A CG  1 
ATOM   223  C CD1 . LEU A 1 29  ? -22.323 -11.564 38.098  1   13.42  ? 25  LEU A CD1 1 
ATOM   224  C CD2 . LEU A 1 29  ? -22.326 -12.907 40.18   1   13.4   ? 25  LEU A CD2 1 
ATOM   225  N N   . THR A 1 30  ? -21.95  -17.105 36.768  1   15.37  ? 26  THR A N   1 
ATOM   226  C CA  . THR A 1 30  ? -22.608 -18.22  36.101  1   17.35  ? 26  THR A CA  1 
ATOM   227  C C   . THR A 1 30  ? -21.878 -19.537 36.356  1   20.15  ? 26  THR A C   1 
ATOM   228  O O   . THR A 1 30  ? -22.477 -20.607 36.228  1   22.84  ? 26  THR A O   1 
ATOM   229  C CB  . THR A 1 30  ? -22.758 -18.009 34.589  1   15.39  ? 26  THR A CB  1 
ATOM   230  O OG1 . THR A 1 30  ? -21.44  -17.987 34.055  1   14.6   ? 26  THR A OG1 1 
ATOM   231  C CG2 . THR A 1 30  ? -23.523 -16.748 34.232  1   14.11  ? 26  THR A CG2 1 
ATOM   232  N N   . GLY A 1 31  ? -20.564 -19.469 36.611  1   20.71  ? 27  GLY A N   1 
ATOM   233  C CA  . GLY A 1 31  ? -19.739 -20.656 36.806  1   18.01  ? 27  GLY A CA  1 
ATOM   234  C C   . GLY A 1 31  ? -18.973 -21.063 35.549  1   17.71  ? 27  GLY A C   1 
ATOM   235  O O   . GLY A 1 31  ? -18.108 -21.931 35.596  1   19.97  ? 27  GLY A O   1 
ATOM   236  N N   . GLU A 1 32  ? -19.257 -20.403 34.43   1   16.61  ? 28  GLU A N   1 
ATOM   237  C CA  . GLU A 1 32  ? -18.758 -20.831 33.133  1   16.03  ? 28  GLU A CA  1 
ATOM   238  C C   . GLU A 1 32  ? -17.242 -20.637 33.044  1   16.79  ? 28  GLU A C   1 
ATOM   239  O O   . GLU A 1 32  ? -16.702 -19.578 33.389  1   16.8   ? 28  GLU A O   1 
ATOM   240  C CB  . GLU A 1 32  ? -19.503 -20.072 32.033  1   15.25  ? 28  GLU A CB  1 
ATOM   241  C CG  . GLU A 1 32  ? -19.181 -20.579 30.635  1   16.28  ? 28  GLU A CG  1 
ATOM   242  C CD  . GLU A 1 32  ? -19.79  -19.801 29.485  1   17.82  ? 28  GLU A CD  1 
ATOM   243  O OE1 . GLU A 1 32  ? -20.254 -18.649 29.664  1   15.79  ? 28  GLU A OE1 1 
ATOM   244  O OE2 . GLU A 1 32  ? -19.734 -20.371 28.361  1   24.01  ? 28  GLU A OE2 1 
ATOM   245  N N   . VAL A 1 33  ? -16.57  -21.692 32.565  1   17.79  ? 29  VAL A N   1 
ATOM   246  C CA  . VAL A 1 33  ? -15.146 -21.676 32.282  1   18.04  ? 29  VAL A CA  1 
ATOM   247  C C   . VAL A 1 33  ? -14.972 -21.183 30.858  1   18.78  ? 29  VAL A C   1 
ATOM   248  O O   . VAL A 1 33  ? -15.532 -21.762 29.939  1   19.41  ? 29  VAL A O   1 
ATOM   249  C CB  . VAL A 1 33  ? -14.481 -23.051 32.468  1   18.57  ? 29  VAL A CB  1 
ATOM   250  C CG1 . VAL A 1 33  ? -12.964 -22.916 32.504  1   20.24  ? 29  VAL A CG1 1 
ATOM   251  C CG2 . VAL A 1 33  ? -14.92  -23.726 33.763  1   17.79  ? 29  VAL A CG2 1 
ATOM   252  N N   . VAL A 1 34  ? -14.198 -20.107 30.703  1   20.27  ? 30  VAL A N   1 
ATOM   253  C CA  . VAL A 1 34  ? -13.931 -19.497 29.403  1   20.32  ? 30  VAL A CA  1 
ATOM   254  C C   . VAL A 1 34  ? -12.419 -19.422 29.162  1   20.84  ? 30  VAL A C   1 
ATOM   255  O O   . VAL A 1 34  ? -11.623 -19.594 30.077  1   21.82  ? 30  VAL A O   1 
ATOM   256  C CB  . VAL A 1 34  ? -14.537 -18.079 29.401  1   18.88  ? 30  VAL A CB  1 
ATOM   257  C CG1 . VAL A 1 34  ? -16.051 -18.122 29.56   1   17.88  ? 30  VAL A CG1 1 
ATOM   258  C CG2 . VAL A 1 34  ? -13.918 -17.204 30.488  1   17.41  ? 30  VAL A CG2 1 
ATOM   259  N N   . ALA A 1 35  ? -12.039 -19.144 27.92   1   21.26  ? 31  ALA A N   1 
ATOM   260  C CA  . ALA A 1 35  ? -10.692 -18.73  27.596  1   20.97  ? 31  ALA A CA  1 
ATOM   261  C C   . ALA A 1 35  ? -10.763 -17.251 27.241  1   22.71  ? 31  ALA A C   1 
ATOM   262  O O   . ALA A 1 35  ? -11.561 -16.907 26.372  1   21.15  ? 31  ALA A O   1 
ATOM   263  C CB  . ALA A 1 35  ? -10.22  -19.521 26.404  1   18.82  ? 31  ALA A CB  1 
ATOM   264  N N   . LEU A 1 36  ? -9.954  -16.412 27.918  1   23.31  ? 32  LEU A N   1 
ATOM   265  C CA  . LEU A 1 36  ? -9.802  -15.005 27.579  1   24.38  ? 32  LEU A CA  1 
ATOM   266  C C   . LEU A 1 36  ? -8.556  -14.82  26.726  1   27.26  ? 32  LEU A C   1 
ATOM   267  O O   . LEU A 1 36  ? -7.476  -15.163 27.169  1   33.48  ? 32  LEU A O   1 
ATOM   268  C CB  . LEU A 1 36  ? -9.635  -14.18  28.846  1   23.1   ? 32  LEU A CB  1 
ATOM   269  C CG  . LEU A 1 36  ? -10.775 -14.214 29.864  1   24.37  ? 32  LEU A CG  1 
ATOM   270  C CD1 . LEU A 1 36  ? -10.384 -13.388 31.094  1   21.48  ? 32  LEU A CD1 1 
ATOM   271  C CD2 . LEU A 1 36  ? -12.094 -13.726 29.29   1   24.17  ? 32  LEU A CD2 1 
ATOM   272  N N   . LYS A 1 37  ? -8.701  -14.287 25.514  1   29.12  ? 33  LYS A N   1 
ATOM   273  C CA  . LYS A 1 37  ? -7.581  -13.819 24.713  1   31.47  ? 33  LYS A CA  1 
ATOM   274  C C   . LYS A 1 37  ? -7.511  -12.308 24.917  1   34.61  ? 33  LYS A C   1 
ATOM   275  O O   . LYS A 1 37  ? -8.494  -11.625 24.66   1   40.5   ? 33  LYS A O   1 
ATOM   276  C CB  . LYS A 1 37  ? -7.826  -14.239 23.253  1   33.93  ? 33  LYS A CB  1 
ATOM   277  C CG  . LYS A 1 37  ? -6.709  -13.971 22.256  1   37.2   ? 33  LYS A CG  1 
ATOM   278  C CD  . LYS A 1 37  ? -6.965  -14.293 20.785  1   44.43  ? 33  LYS A CD  1 
ATOM   279  C CE  . LYS A 1 37  ? -7.297  -15.727 20.468  1   50.64  ? 33  LYS A CE  1 
ATOM   280  N NZ  . LYS A 1 37  ? -7.189  -16.05  19.041  1   46.04  ? 33  LYS A NZ  1 
ATOM   281  N N   . LYS A 1 38  ? -6.386  -11.813 25.45   1   36.43  ? 34  LYS A N   1 
ATOM   282  C CA  . LYS A 1 38  ? -6.092  -10.391 25.571  1   38.86  ? 34  LYS A CA  1 
ATOM   283  C C   . LYS A 1 38  ? -5.375  -9.916  24.311  1   45.23  ? 34  LYS A C   1 
ATOM   284  O O   . LYS A 1 38  ? -4.525  -10.635 23.796  1   53.33  ? 34  LYS A O   1 
ATOM   285  C CB  . LYS A 1 38  ? -5.189  -10.137 26.784  1   38.35  ? 34  LYS A CB  1 
ATOM   286  C CG  . LYS A 1 38  ? -4.974  -8.672  27.148  1   44.96  ? 34  LYS A CG  1 
ATOM   287  C CD  . LYS A 1 38  ? -4.297  -8.429  28.495  1   50.79  ? 34  LYS A CD  1 
ATOM   288  C CE  . LYS A 1 38  ? -2.833  -8.768  28.533  1   57.16  ? 34  LYS A CE  1 
ATOM   289  N NZ  . LYS A 1 38  ? -2.313  -8.977  29.894  1   49.83  ? 34  LYS A NZ  1 
ATOM   290  N N   . ILE A 1 39  ? -5.743  -8.72   23.819  1   48.31  ? 35  ILE A N   1 
ATOM   291  C CA  . ILE A 1 39  ? -5.135  -8.061  22.67   1   44.38  ? 35  ILE A CA  1 
ATOM   292  C C   . ILE A 1 39  ? -4.894  -6.599  23.058  1   47.27  ? 35  ILE A C   1 
ATOM   293  O O   . ILE A 1 39  ? -5.805  -5.783  22.965  1   49.96  ? 35  ILE A O   1 
ATOM   294  C CB  . ILE A 1 39  ? -6.011  -8.225  21.402  1   38.54  ? 35  ILE A CB  1 
ATOM   295  C CG1 . ILE A 1 39  ? -6.126  -9.711  20.972  1   38.42  ? 35  ILE A CG1 1 
ATOM   296  C CG2 . ILE A 1 39  ? -5.479  -7.368  20.25   1   34.65  ? 35  ILE A CG2 1 
ATOM   297  C CD1 . ILE A 1 39  ? -7.422  -10.088 20.266  1   32.68  ? 35  ILE A CD1 1 
ATOM   298  N N   . ARG A 1 40  ? -3.679  -6.291  23.511  1   54.45  ? 36  ARG A N   1 
ATOM   299  C CA  . ARG A 1 40  ? -3.344  -4.914  23.954  1   61.2   ? 36  ARG A CA  1 
ATOM   300  C C   . ARG A 1 40  ? -3.34   -3.962  22.755  1   64.64  ? 36  ARG A C   1 
ATOM   301  O O   . ARG A 1 40  ? -2.661  -4.258  21.75   1   65.65  ? 36  ARG A O   1 
ATOM   302  C CB  . ARG A 1 40  ? -1.966  -4.863  24.615  1   62.61  ? 36  ARG A CB  1 
ATOM   303  C CG  . ARG A 1 40  ? -1.998  -5.099  26.116  1   74.67  ? 36  ARG A CG  1 
ATOM   304  C CD  . ARG A 1 40  ? -0.635  -5.47   26.669  1   85.01  ? 36  ARG A CD  1 
ATOM   305  N NE  . ARG A 1 40  ? -0.719  -5.933  28.058  1   79.79  ? 36  ARG A NE  1 
ATOM   306  C CZ  . ARG A 1 40  ? -1.13   -5.187  29.075  1   77.96  ? 36  ARG A CZ  1 
ATOM   307  N NH1 . ARG A 1 40  ? -1.835  -5.729  30.051  1   81.3   ? 36  ARG A NH1 1 
ATOM   308  N NH2 . ARG A 1 40  ? -0.832  -3.902  29.117  1   73.24  ? 36  ARG A NH2 1 
ATOM   309  N N   . LEU A 1 41  ? -4.067  -2.857  22.875  1   61.71  ? 37  LEU A N   1 
ATOM   310  C CA  . LEU A 1 41  ? -4.137  -1.878  21.768  1   68.13  ? 37  LEU A CA  1 
ATOM   311  C C   . LEU A 1 41  ? -3.232  -0.689  22.111  1   86.55  ? 37  LEU A C   1 
ATOM   312  O O   . LEU A 1 41  ? -2.811  0.019   21.183  1   93.78  ? 37  LEU A O   1 
ATOM   313  C CB  . LEU A 1 41  ? -5.593  -1.472  21.569  1   59.46  ? 37  LEU A CB  1 
ATOM   314  C CG  . LEU A 1 41  ? -6.62   -2.602  21.67   1   49.2   ? 37  LEU A CG  1 
ATOM   315  C CD1 . LEU A 1 41  ? -7.977  -2.062  22.073  1   48.26  ? 37  LEU A CD1 1 
ATOM   316  C CD2 . LEU A 1 41  ? -6.706  -3.338  20.349  1   50.12  ? 37  LEU A CD2 1 
ATOM   317  N N   . ASP A 1 42  ? -2.954  -0.476  23.397  1   96.34  ? 38  ASP A N   1 
ATOM   318  C CA  . ASP A 1 42  ? -2.016  0.603   23.801  1   97.14  ? 38  ASP A CA  1 
ATOM   319  C C   . ASP A 1 42  ? -0.711  0.392   23.037  1   102.52 ? 38  ASP A C   1 
ATOM   320  O O   . ASP A 1 42  ? -0.191  1.373   22.466  1   96.95  ? 38  ASP A O   1 
ATOM   321  C CB  . ASP A 1 42  ? -1.813  0.6     25.304  1   96.42  ? 38  ASP A CB  1 
ATOM   322  C CG  . ASP A 1 42  ? -1.761  -0.773  25.959  1   99.89  ? 38  ASP A CG  1 
ATOM   323  O OD1 . ASP A 1 42  ? -1.361  -1.734  25.275  1   107.29 ? 38  ASP A OD1 1 
ATOM   324  O OD2 . ASP A 1 42  ? -2.115  -0.872  27.151  1   96.16  ? 38  ASP A OD2 1 
ATOM   325  N N   . THR A 1 43  ? -0.203  -0.841  23.036  1   105.25 ? 39  THR A N   1 
ATOM   326  C CA  . THR A 1 43  ? 1.02    -1.174  22.287  1   102.36 ? 39  THR A CA  1 
ATOM   327  C C   . THR A 1 43  ? 0.805   -0.83   20.842  1   109.77 ? 39  THR A C   1 
ATOM   328  O O   . THR A 1 43  ? 1.711   -0.221  20.243  1   117.54 ? 39  THR A O   1 
ATOM   329  C CB  . THR A 1 43  ? 1.269   -2.67   22.443  1   97.57  ? 39  THR A CB  1 
ATOM   330  O OG1 . THR A 1 43  ? 1.684   -2.839  23.795  1   94.23  ? 39  THR A OG1 1 
ATOM   331  C CG2 . THR A 1 43  ? 2.334   -3.188  21.493  1   93.14  ? 39  THR A CG2 1 
ATOM   332  N N   . GLU A 1 44  ? -0.365  -1.174  20.3    1   107.22 ? 40  GLU A N   1 
ATOM   333  C CA  . GLU A 1 44  ? -0.627  -0.972  18.852  1   91.86  ? 40  GLU A CA  1 
ATOM   334  C C   . GLU A 1 44  ? -0.655  0.517   18.489  1   84.05  ? 40  GLU A C   1 
ATOM   335  O O   . GLU A 1 44  ? -1.48   1.256   19.057  1   77.82  ? 40  GLU A O   1 
ATOM   336  C CB  . GLU A 1 44  ? -1.947  -1.646  18.494  1   85.76  ? 40  GLU A CB  1 
ATOM   337  C CG  . GLU A 1 44  ? -1.786  -3.108  18.093  1   89.61  ? 40  GLU A CG  1 
ATOM   338  C CD  . GLU A 1 44  ? -1.405  -3.309  16.638  1   95.06  ? 40  GLU A CD  1 
ATOM   339  O OE1 . GLU A 1 44  ? -0.356  -3.937  16.394  1   95.72  ? 40  GLU A OE1 1 
ATOM   340  O OE2 . GLU A 1 44  ? -2.148  -2.841  15.75   1   92.13  ? 40  GLU A OE2 1 
ATOM   341  N N   . THR A 1 45  ? 0.208   0.926   17.561  1   77.54  ? 41  THR A N   1 
ATOM   342  C CA  . THR A 1 45  ? 0.2     2.32    17.073  1   68.51  ? 41  THR A CA  1 
ATOM   343  C C   . THR A 1 45  ? -0.612  2.372   15.798  1   55.39  ? 41  THR A C   1 
ATOM   344  O O   . THR A 1 45  ? -0.846  3.47    15.294  1   51.68  ? 41  THR A O   1 
ATOM   345  C CB  . THR A 1 45  ? 1.644   2.762   16.851  1   71.53  ? 41  THR A CB  1 
ATOM   346  O OG1 . THR A 1 45  ? 2.205   1.863   15.899  1   80.66  ? 41  THR A OG1 1 
ATOM   347  C CG2 . THR A 1 45  ? 2.466   2.718   18.127  1   63.97  ? 41  THR A CG2 1 
ATOM   348  N N   . GLU A 1 46  ? -1.027  1.214   15.288  1   44.77  ? 42  GLU A N   1 
ATOM   349  C CA  . GLU A 1 46  ? -1.822  1.16    14.038  1   39.1   ? 42  GLU A CA  1 
ATOM   350  C C   . GLU A 1 46  ? -3.278  0.842   14.39   1   33.84  ? 42  GLU A C   1 
ATOM   351  O O   . GLU A 1 46  ? -3.997  0.337   13.522  1   31.05  ? 42  GLU A O   1 
ATOM   352  C CB  . GLU A 1 46  ? -1.13   0.172   13.107  1   40.17  ? 42  GLU A CB  1 
ATOM   353  C CG  . GLU A 1 46  ? 0.062   0.785   12.377  1   41.14  ? 42  GLU A CG  1 
ATOM   354  C CD  . GLU A 1 46  ? -0.257  1.998   11.521  1   37.22  ? 42  GLU A CD  1 
ATOM   355  O OE1 . GLU A 1 46  ? -0.802  1.816   10.415  1   32.12  ? 42  GLU A OE1 1 
ATOM   356  O OE2 . GLU A 1 46  ? 0.044   3.125   11.958  1   37.15  ? 42  GLU A OE2 1 
ATOM   357  N N   . GLY A 1 47  ? -3.681  1.135   15.618  1   31.79  ? 43  GLY A N   1 
ATOM   358  C CA  . GLY A 1 47  ? -5.047  0.939   16.074  1   25.94  ? 43  GLY A CA  1 
ATOM   359  C C   . GLY A 1 47  ? -5.38   -0.54   16.215  1   24.36  ? 43  GLY A C   1 
ATOM   360  O O   . GLY A 1 47  ? -4.52   -1.34   16.569  1   26.09  ? 43  GLY A O   1 
ATOM   361  N N   . VAL A 1 48  ? -6.64   -0.899  15.947  1   20.47  ? 44  VAL A N   1 
ATOM   362  C CA  . VAL A 1 48  ? -7.051  -2.261  16.201  1   17.7   ? 44  VAL A CA  1 
ATOM   363  C C   . VAL A 1 48  ? -6.503  -3.136  15.082  1   18.48  ? 44  VAL A C   1 
ATOM   364  O O   . VAL A 1 48  ? -6.736  -2.875  13.904  1   17.81  ? 44  VAL A O   1 
ATOM   365  C CB  . VAL A 1 48  ? -8.568  -2.408  16.421  1   16.58  ? 44  VAL A CB  1 
ATOM   366  C CG1 . VAL A 1 48  ? -9.011  -3.863  16.535  1   15.82  ? 44  VAL A CG1 1 
ATOM   367  C CG2 . VAL A 1 48  ? -9.03   -1.641  17.646  1   16.17  ? 44  VAL A CG2 1 
ATOM   368  N N   . PRO A 1 49  ? -5.738  -4.191  15.429  1   20.58  ? 45  PRO A N   1 
ATOM   369  C CA  . PRO A 1 49  ? -5.062  -5.034  14.44   1   22     ? 45  PRO A CA  1 
ATOM   370  C C   . PRO A 1 49  ? -6.037  -5.729  13.492  1   24.02  ? 45  PRO A C   1 
ATOM   371  O O   . PRO A 1 49  ? -7.128  -6.138  13.892  1   25.35  ? 45  PRO A O   1 
ATOM   372  C CB  . PRO A 1 49  ? -4.236  -6.02   15.307  1   20.29  ? 45  PRO A CB  1 
ATOM   373  C CG  . PRO A 1 49  ? -4.985  -6.041  16.603  1   20.58  ? 45  PRO A CG  1 
ATOM   374  C CD  . PRO A 1 49  ? -5.472  -4.612  16.808  1   20.93  ? 45  PRO A CD  1 
ATOM   375  N N   . SER A 1 50  ? -5.632  -5.859  12.228  1   24.52  ? 46  SER A N   1 
ATOM   376  C CA  . SER A 1 50  ? -6.502  -6.424  11.209  1   24.56  ? 46  SER A CA  1 
ATOM   377  C C   . SER A 1 50  ? -6.842  -7.882  11.525  1   24.07  ? 46  SER A C   1 
ATOM   378  O O   . SER A 1 50  ? -7.965  -8.33   11.293  1   24.67  ? 46  SER A O   1 
ATOM   379  C CB  . SER A 1 50  ? -5.908  -6.237  9.831   1   25.02  ? 46  SER A CB  1 
ATOM   380  O OG  . SER A 1 50  ? -4.649  -6.893  9.738   1   26.84  ? 46  SER A OG  1 
ATOM   381  N N   . THR A 1 51  ? -5.871  -8.626  12.072  1   24.53  ? 47  THR A N   1 
ATOM   382  C CA  . THR A 1 51  ? -6.125  -9.998  12.49   1   23.52  ? 47  THR A CA  1 
ATOM   383  C C   . THR A 1 51  ? -7.332  -10.03  13.419  1   21.57  ? 47  THR A C   1 
ATOM   384  O O   . THR A 1 51  ? -8.246  -10.816 13.196  1   21.25  ? 47  THR A O   1 
ATOM   385  C CB  . THR A 1 51  ? -4.907  -10.684 13.103  1   26.98  ? 47  THR A CB  1 
ATOM   386  O OG1 . THR A 1 51  ? -4.3    -9.755  13.995  1   32.53  ? 47  THR A OG1 1 
ATOM   387  C CG2 . THR A 1 51  ? -3.845  -11.01  12.069  1   31.66  ? 47  THR A CG2 1 
ATOM   388  N N   . ALA A 1 52  ? -7.338  -9.154  14.43   1   20.81  ? 48  ALA A N   1 
ATOM   389  C CA  . ALA A 1 52  ? -8.402  -9.124  15.438  1   22.1   ? 48  ALA A CA  1 
ATOM   390  C C   . ALA A 1 52  ? -9.758  -8.695  14.853  1   20.69  ? 48  ALA A C   1 
ATOM   391  O O   . ALA A 1 52  ? -10.784 -9.243  15.23   1   21.87  ? 48  ALA A O   1 
ATOM   392  C CB  . ALA A 1 52  ? -8      -8.256  16.631  1   19.37  ? 48  ALA A CB  1 
ATOM   393  N N   . ILE A 1 53  ? -9.754  -7.702  13.956  1   18.15  ? 49  ILE A N   1 
ATOM   394  C CA  . ILE A 1 53  ? -10.934 -7.269  13.226  1   18.75  ? 49  ILE A CA  1 
ATOM   395  C C   . ILE A 1 53  ? -11.569 -8.424  12.439  1   20.78  ? 49  ILE A C   1 
ATOM   396  O O   . ILE A 1 53  ? -12.782 -8.631  12.51   1   22.06  ? 49  ILE A O   1 
ATOM   397  C CB  . ILE A 1 53  ? -10.576 -6.068  12.339  1   17.1   ? 49  ILE A CB  1 
ATOM   398  C CG1 . ILE A 1 53  ? -10.489 -4.809  13.196  1   15.5   ? 49  ILE A CG1 1 
ATOM   399  C CG2 . ILE A 1 53  ? -11.615 -5.937  11.234  1   17.28  ? 49  ILE A CG2 1 
ATOM   400  C CD1 . ILE A 1 53  ? -9.913  -3.602  12.504  1   14.79  ? 49  ILE A CD1 1 
ATOM   401  N N   . ARG A 1 54  ? -10.748 -9.198  11.72   1   20.39  ? 50  ARG A N   1 
ATOM   402  C CA  . ARG A 1 54  ? -11.259 -10.351 11.005  1   19.66  ? 50  ARG A CA  1 
ATOM   403  C C   . ARG A 1 54  ? -11.755 -11.445 11.95   1   21.11  ? 50  ARG A C   1 
ATOM   404  O O   . ARG A 1 54  ? -12.815 -12.012 11.734  1   20.52  ? 50  ARG A O   1 
ATOM   405  C CB  . ARG A 1 54  ? -10.201 -10.884 10.049  1   18.59  ? 50  ARG A CB  1 
ATOM   406  C CG  . ARG A 1 54  ? -9.979  -9.919  8.895   1   18.91  ? 50  ARG A CG  1 
ATOM   407  C CD  . ARG A 1 54  ? -9.014  -10.54  7.901   1   18.49  ? 50  ARG A CD  1 
ATOM   408  N NE  . ARG A 1 54  ? -8.776  -9.727  6.711   1   17.33  ? 50  ARG A NE  1 
ATOM   409  C CZ  . ARG A 1 54  ? -7.753  -9.942  5.903   1   17.84  ? 50  ARG A CZ  1 
ATOM   410  N NH1 . ARG A 1 54  ? -6.868  -10.907 6.152   1   16.64  ? 50  ARG A NH1 1 
ATOM   411  N NH2 . ARG A 1 54  ? -7.594  -9.147  4.866   1   17.06  ? 50  ARG A NH2 1 
ATOM   412  N N   . GLU A 1 55  ? -10.992 -11.749 13.002  1   24.12  ? 51  GLU A N   1 
ATOM   413  C CA  . GLU A 1 55  ? -11.372 -12.811 13.924  1   23.73  ? 51  GLU A CA  1 
ATOM   414  C C   . GLU A 1 55  ? -12.744 -12.495 14.527  1   21.91  ? 51  GLU A C   1 
ATOM   415  O O   . GLU A 1 55  ? -13.649 -13.323 14.486  1   21.88  ? 51  GLU A O   1 
ATOM   416  C CB  . GLU A 1 55  ? -10.271 -13.093 14.947  1   22.24  ? 51  GLU A CB  1 
ATOM   417  C CG  . GLU A 1 55  ? -10.666 -14.218 15.89   1   25.63  ? 51  GLU A CG  1 
ATOM   418  C CD  . GLU A 1 55  ? -9.553  -14.902 16.661  1   29.45  ? 51  GLU A CD  1 
ATOM   419  O OE1 . GLU A 1 55  ? -8.629  -14.195 17.099  1   26.1   ? 51  GLU A OE1 1 
ATOM   420  O OE2 . GLU A 1 55  ? -9.656  -16.154 16.844  1   36.99  ? 51  GLU A OE2 1 
ATOM   421  N N   . ILE A 1 56  ? -12.906 -11.281 15.058  1   19.91  ? 52  ILE A N   1 
ATOM   422  C CA  . ILE A 1 56  ? -14.147 -10.94  15.726  1   21.93  ? 52  ILE A CA  1 
ATOM   423  C C   . ILE A 1 56  ? -15.295 -10.911 14.711  1   23.65  ? 52  ILE A C   1 
ATOM   424  O O   . ILE A 1 56  ? -16.273 -11.624 14.902  1   24.77  ? 52  ILE A O   1 
ATOM   425  C CB  . ILE A 1 56  ? -14.037 -9.637  16.534  1   21     ? 52  ILE A CB  1 
ATOM   426  C CG1 . ILE A 1 56  ? -12.843 -9.678  17.476  1   20.82  ? 52  ILE A CG1 1 
ATOM   427  C CG2 . ILE A 1 56  ? -15.341 -9.405  17.292  1   20.21  ? 52  ILE A CG2 1 
ATOM   428  C CD1 . ILE A 1 56  ? -12.422 -8.338  18.033  1   21.52  ? 52  ILE A CD1 1 
ATOM   429  N N   . SER A 1 57  ? -15.18  -10.107 13.642  1   24.21  ? 53  SER A N   1 
ATOM   430  C CA  . SER A 1 57  ? -16.258 -9.997  12.662  1   27.12  ? 53  SER A CA  1 
ATOM   431  C C   . SER A 1 57  ? -16.67  -11.358 12.092  1   25.85  ? 53  SER A C   1 
ATOM   432  O O   . SER A 1 57  ? -17.854 -11.599 11.841  1   30.12  ? 53  SER A O   1 
ATOM   433  C CB  . SER A 1 57  ? -15.942 -9.019  11.559  1   27.37  ? 53  SER A CB  1 
ATOM   434  O OG  . SER A 1 57  ? -14.779 -9.456  10.876  1   29.8   ? 53  SER A OG  1 
ATOM   435  N N   . LEU A 1 58  ? -15.703 -12.248 11.886  1   22.51  ? 54  LEU A N   1 
ATOM   436  C CA  . LEU A 1 58  ? -16.029 -13.511 11.267  1   23.4   ? 54  LEU A CA  1 
ATOM   437  C C   . LEU A 1 58  ? -16.594 -14.503 12.278  1   27.68  ? 54  LEU A C   1 
ATOM   438  O O   . LEU A 1 58  ? -17.524 -15.238 11.924  1   30.02  ? 54  LEU A O   1 
ATOM   439  C CB  . LEU A 1 58  ? -14.909 -14.098 10.431  1   19.63  ? 54  LEU A CB  1 
ATOM   440  C CG  . LEU A 1 58  ? -14.391 -13.171 9.331   1   21.37  ? 54  LEU A CG  1 
ATOM   441  C CD1 . LEU A 1 58  ? -13.161 -13.763 8.652   1   20.06  ? 54  LEU A CD1 1 
ATOM   442  C CD2 . LEU A 1 58  ? -15.489 -12.889 8.342   1   20.01  ? 54  LEU A CD2 1 
ATOM   443  N N   . LEU A 1 59  ? -16.068 -14.516 13.513  1   28.9   ? 55  LEU A N   1 
ATOM   444  C CA  . LEU A 1 59  ? -16.543 -15.472 14.513  1   29.75  ? 55  LEU A CA  1 
ATOM   445  C C   . LEU A 1 59  ? -17.952 -15.146 15.013  1   31.58  ? 55  LEU A C   1 
ATOM   446  O O   . LEU A 1 59  ? -18.709 -16.042 15.389  1   30.11  ? 55  LEU A O   1 
ATOM   447  C CB  . LEU A 1 59  ? -15.564 -15.593 15.67   1   28.36  ? 55  LEU A CB  1 
ATOM   448  C CG  . LEU A 1 59  ? -14.443 -16.603 15.437  1   30.79  ? 55  LEU A CG  1 
ATOM   449  C CD1 . LEU A 1 59  ? -13.478 -16.597 16.614  1   29.87  ? 55  LEU A CD1 1 
ATOM   450  C CD2 . LEU A 1 59  ? -15.005 -17.984 15.182  1   31.6   ? 55  LEU A CD2 1 
ATOM   451  N N   . LYS A 1 60  ? -18.284 -13.853 15.037  1   35.04  ? 56  LYS A N   1 
ATOM   452  C CA  . LYS A 1 60  ? -19.627 -13.384 15.325  1   38.06  ? 56  LYS A CA  1 
ATOM   453  C C   . LYS A 1 60  ? -20.688 -14.243 14.638  1   42.94  ? 56  LYS A C   1 
ATOM   454  O O   . LYS A 1 60  ? -21.605 -14.727 15.298  1   45.37  ? 56  LYS A O   1 
ATOM   455  C CB  . LYS A 1 60  ? -19.783 -11.899 14.984  1   37.93  ? 56  LYS A CB  1 
ATOM   456  C CG  . LYS A 1 60  ? -19.488 -11.018 16.194  1   38.4   ? 56  LYS A CG  1 
ATOM   457  C CD  . LYS A 1 60  ? -20.444 -9.834  16.177  1   44.89  ? 56  LYS A CD  1 
ATOM   458  C CE  . LYS A 1 60  ? -20.684 -9.294  17.551  1   49.6   ? 56  LYS A CE  1 
ATOM   459  N NZ  . LYS A 1 60  ? -21.833 -8.38   17.522  1   48.92  ? 56  LYS A NZ  1 
ATOM   460  N N   . GLU A 1 61  ? -20.56  -14.439 13.322  1   47.86  ? 57  GLU A N   1 
ATOM   461  C CA  . GLU A 1 61  ? -21.641 -15.036 12.548  1   57.49  ? 57  GLU A CA  1 
ATOM   462  C C   . GLU A 1 61  ? -21.429 -16.53  12.279  1   47.44  ? 57  GLU A C   1 
ATOM   463  O O   . GLU A 1 61  ? -22.243 -17.16  11.601  1   50.63  ? 57  GLU A O   1 
ATOM   464  C CB  . GLU A 1 61  ? -21.867 -14.213 11.282  1   71.95  ? 57  GLU A CB  1 
ATOM   465  C CG  . GLU A 1 61  ? -20.609 -13.455 10.87   1   78.16  ? 57  GLU A CG  1 
ATOM   466  C CD  . GLU A 1 61  ? -20.694 -12.701 9.555   1   86.15  ? 57  GLU A CD  1 
ATOM   467  O OE1 . GLU A 1 61  ? -21.717 -12.095 9.156   1   87.9   ? 57  GLU A OE1 1 
ATOM   468  O OE2 . GLU A 1 61  ? -19.637 -12.727 8.912   1   110.21 ? 57  GLU A OE2 1 
ATOM   469  N N   . LEU A 1 62  ? -20.382 -17.115 12.862  1   35.66  ? 58  LEU A N   1 
ATOM   470  C CA  . LEU A 1 62  ? -20.137 -18.54  12.714  1   31.11  ? 58  LEU A CA  1 
ATOM   471  C C   . LEU A 1 62  ? -20.511 -19.26  13.998  1   29.41  ? 58  LEU A C   1 
ATOM   472  O O   . LEU A 1 62  ? -19.648 -19.518 14.82   1   33.9   ? 58  LEU A O   1 
ATOM   473  C CB  . LEU A 1 62  ? -18.669 -18.82  12.395  1   28.61  ? 58  LEU A CB  1 
ATOM   474  C CG  . LEU A 1 62  ? -18.181 -18.349 11.03   1   31.21  ? 58  LEU A CG  1 
ATOM   475  C CD1 . LEU A 1 62  ? -16.721 -18.676 10.887  1   30.96  ? 58  LEU A CD1 1 
ATOM   476  C CD2 . LEU A 1 62  ? -18.954 -18.968 9.882   1   29.02  ? 58  LEU A CD2 1 
ATOM   477  N N   A ASN A 1 63  ? -21.793 -19.594 14.137  0.5 27.99  ? 59  ASN A N   1 
ATOM   478  N N   B ASN A 1 63  ? -21.801 -19.561 14.184  0.5 28.95  ? 59  ASN A N   1 
ATOM   479  C CA  A ASN A 1 63  ? -22.269 -20.373 15.264  0.5 25.83  ? 59  ASN A CA  1 
ATOM   480  C CA  B ASN A 1 63  ? -22.221 -20.371 15.318  0.5 27.24  ? 59  ASN A CA  1 
ATOM   481  C C   A ASN A 1 63  ? -22.406 -21.826 14.824  0.5 24.42  ? 59  ASN A C   1 
ATOM   482  C C   B ASN A 1 63  ? -22.389 -21.808 14.834  0.5 25.17  ? 59  ASN A C   1 
ATOM   483  O O   A ASN A 1 63  ? -23.246 -22.163 13.994  0.5 26.18  ? 59  ASN A O   1 
ATOM   484  O O   B ASN A 1 63  ? -23.216 -22.111 13.977  0.5 26.92  ? 59  ASN A O   1 
ATOM   485  C CB  A ASN A 1 63  ? -23.558 -19.772 15.809  0.5 24.93  ? 59  ASN A CB  1 
ATOM   486  C CB  B ASN A 1 63  ? -23.406 -19.767 16.074  0.5 27.97  ? 59  ASN A CB  1 
ATOM   487  C CG  A ASN A 1 63  ? -23.329 -18.357 16.27   0.5 25.39  ? 59  ASN A CG  1 
ATOM   488  C CG  B ASN A 1 63  ? -23.788 -20.539 17.324  0.5 30.25  ? 59  ASN A CG  1 
ATOM   489  O OD1 A ASN A 1 63  ? -23.757 -17.411 15.598  0.5 25.46  ? 59  ASN A OD1 1 
ATOM   490  O OD1 B ASN A 1 63  ? -22.921 -21.002 18.084  0.5 32.19  ? 59  ASN A OD1 1 
ATOM   491  N ND2 A ASN A 1 63  ? -22.627 -18.197 17.384  0.5 27.62  ? 59  ASN A ND2 1 
ATOM   492  N ND2 B ASN A 1 63  ? -25.084 -20.679 17.559  0.5 31.29  ? 59  ASN A ND2 1 
ATOM   493  N N   . HIS A 1 64  ? -21.559 -22.689 15.373  1   23.25  ? 60  HIS A N   1 
ATOM   494  C CA  . HIS A 1 64  ? -21.563 -24.07  14.942  1   23.92  ? 60  HIS A CA  1 
ATOM   495  C C   . HIS A 1 64  ? -20.888 -24.886 16.037  1   24.81  ? 60  HIS A C   1 
ATOM   496  O O   . HIS A 1 64  ? -19.897 -24.461 16.627  1   24.51  ? 60  HIS A O   1 
ATOM   497  C CB  . HIS A 1 64  ? -20.889 -24.236 13.564  1   22.72  ? 60  HIS A CB  1 
ATOM   498  C CG  . HIS A 1 64  ? -21.045 -25.63  13.033  1   22.26  ? 60  HIS A CG  1 
ATOM   499  N ND1 . HIS A 1 64  ? -20.226 -26.676 13.426  1   22.35  ? 60  HIS A ND1 1 
ATOM   500  C CD2 . HIS A 1 64  ? -21.934 -26.16  12.18   1   19.9   ? 60  HIS A CD2 1 
ATOM   501  C CE1 . HIS A 1 64  ? -20.611 -27.796 12.816  1   21.8   ? 60  HIS A CE1 1 
ATOM   502  N NE2 . HIS A 1 64  ? -21.646 -27.506 12.057  1   20.02  ? 60  HIS A NE2 1 
ATOM   503  N N   . PRO A 1 65  ? -21.423 -26.08  16.362  1   25.26  ? 61  PRO A N   1 
ATOM   504  C CA  . PRO A 1 65  ? -20.829 -26.882 17.425  1   24.48  ? 61  PRO A CA  1 
ATOM   505  C C   . PRO A 1 65  ? -19.376 -27.303 17.198  1   25.5   ? 61  PRO A C   1 
ATOM   506  O O   . PRO A 1 65  ? -18.716 -27.678 18.155  1   27.87  ? 61  PRO A O   1 
ATOM   507  C CB  . PRO A 1 65  ? -21.82  -28.03  17.664  1   22.15  ? 61  PRO A CB  1 
ATOM   508  C CG  . PRO A 1 65  ? -22.596 -28.087 16.376  1   23.55  ? 61  PRO A CG  1 
ATOM   509  C CD  . PRO A 1 65  ? -22.621 -26.69  15.761  1   23.04  ? 61  PRO A CD  1 
ATOM   510  N N   . ASN A 1 66  ? -18.854 -27.155 15.974  1   24.68  ? 62  ASN A N   1 
ATOM   511  C CA  . ASN A 1 66  ? -17.493 -27.572 15.67   1   23.51  ? 62  ASN A CA  1 
ATOM   512  C C   . ASN A 1 66  ? -16.636 -26.364 15.299  1   23.64  ? 62  ASN A C   1 
ATOM   513  O O   . ASN A 1 66  ? -15.574 -26.491 14.671  1   24.13  ? 62  ASN A O   1 
ATOM   514  C CB  . ASN A 1 66  ? -17.484 -28.67  14.613  1   25.1   ? 62  ASN A CB  1 
ATOM   515  C CG  . ASN A 1 66  ? -18.156 -29.904 15.157  1   28.27  ? 62  ASN A CG  1 
ATOM   516  O OD1 . ASN A 1 66  ? -19.195 -30.334 14.645  1   31.01  ? 62  ASN A OD1 1 
ATOM   517  N ND2 . ASN A 1 66  ? -17.617 -30.466 16.228  1   27.54  ? 62  ASN A ND2 1 
ATOM   518  N N   . ILE A 1 67  ? -17.116 -25.181 15.69   1   23.28  ? 63  ILE A N   1 
ATOM   519  C CA  . ILE A 1 67  ? -16.348 -23.951 15.618  1   23.4   ? 63  ILE A CA  1 
ATOM   520  C C   . ILE A 1 67  ? -16.366 -23.387 17.032  1   28.6   ? 63  ILE A C   1 
ATOM   521  O O   . ILE A 1 67  ? -17.43  -23.355 17.65   1   36.91  ? 63  ILE A O   1 
ATOM   522  C CB  . ILE A 1 67  ? -16.913 -22.976 14.569  1   20.03  ? 63  ILE A CB  1 
ATOM   523  C CG1 . ILE A 1 67  ? -16.952 -23.573 13.175  1   19.72  ? 63  ILE A CG1 1 
ATOM   524  C CG2 . ILE A 1 67  ? -16.132 -21.666 14.553  1   21.42  ? 63  ILE A CG2 1 
ATOM   525  C CD1 . ILE A 1 67  ? -17.611 -22.676 12.129  1   17.52  ? 63  ILE A CD1 1 
ATOM   526  N N   . VAL A 1 68  ? -15.185 -23.017 17.554  1   29.23  ? 64  VAL A N   1 
ATOM   527  C CA  . VAL A 1 68  ? -15.054 -22.465 18.899  1   28.73  ? 64  VAL A CA  1 
ATOM   528  C C   . VAL A 1 68  ? -15.92  -21.208 18.97   1   26.68  ? 64  VAL A C   1 
ATOM   529  O O   . VAL A 1 68  ? -15.897 -20.385 18.056  1   26.76  ? 64  VAL A O   1 
ATOM   530  C CB  . VAL A 1 68  ? -13.576 -22.127 19.198  1   33.05  ? 64  VAL A CB  1 
ATOM   531  C CG1 . VAL A 1 68  ? -13.047 -21.046 18.233  1   37.99  ? 64  VAL A CG1 1 
ATOM   532  C CG2 . VAL A 1 68  ? -13.348 -21.722 20.65   1   28.22  ? 64  VAL A CG2 1 
ATOM   533  N N   . LYS A 1 69  ? -16.673 -21.062 20.061  1   26.1   ? 65  LYS A N   1 
ATOM   534  C CA  . LYS A 1 69  ? -17.621 -19.966 20.156  1   26.5   ? 65  LYS A CA  1 
ATOM   535  C C   . LYS A 1 69  ? -16.995 -18.732 20.804  1   27.16  ? 65  LYS A C   1 
ATOM   536  O O   . LYS A 1 69  ? -16.488 -18.796 21.93   1   30.36  ? 65  LYS A O   1 
ATOM   537  C CB  . LYS A 1 69  ? -18.877 -20.395 20.917  1   26.01  ? 65  LYS A CB  1 
ATOM   538  C CG  . LYS A 1 69  ? -19.999 -19.355 20.78   1   32.07  ? 65  LYS A CG  1 
ATOM   539  C CD  . LYS A 1 69  ? -21.384 -19.958 20.971  1   37.95  ? 65  LYS A CD  1 
ATOM   540  C CE  . LYS A 1 69  ? -22.454 -18.944 21.25   1   39.87  ? 65  LYS A CE  1 
ATOM   541  N NZ  . LYS A 1 69  ? -22.981 -18.378 20.004  1   40.62  ? 65  LYS A NZ  1 
ATOM   542  N N   . LEU A 1 70  ? -17.07  -17.599 20.092  1   24.81  ? 66  LEU A N   1 
ATOM   543  C CA  . LEU A 1 70  ? -16.842 -16.29  20.691  1   22.47  ? 66  LEU A CA  1 
ATOM   544  C C   . LEU A 1 70  ? -18.081 -15.926 21.507  1   21.74  ? 66  LEU A C   1 
ATOM   545  O O   . LEU A 1 70  ? -19.168 -15.817 20.948  1   20.28  ? 66  LEU A O   1 
ATOM   546  C CB  . LEU A 1 70  ? -16.62  -15.281 19.564  1   21.8   ? 66  LEU A CB  1 
ATOM   547  C CG  . LEU A 1 70  ? -16.157 -13.888 20.003  1   22.17  ? 66  LEU A CG  1 
ATOM   548  C CD1 . LEU A 1 70  ? -14.819 -13.948 20.734  1   22.4   ? 66  LEU A CD1 1 
ATOM   549  C CD2 . LEU A 1 70  ? -16.042 -12.97  18.815  1   22.63  ? 66  LEU A CD2 1 
ATOM   550  N N   . LEU A 1 71  ? -17.907 -15.762 22.819  1   20.38  ? 67  LEU A N   1 
ATOM   551  C CA  . LEU A 1 71  ? -19.013 -15.493 23.72   1   20.01  ? 67  LEU A CA  1 
ATOM   552  C C   . LEU A 1 71  ? -19.209 -13.994 23.891  1   18.98  ? 67  LEU A C   1 
ATOM   553  O O   . LEU A 1 71  ? -20.337 -13.556 24.036  1   18.91  ? 67  LEU A O   1 
ATOM   554  C CB  . LEU A 1 71  ? -18.788 -16.189 25.063  1   20.65  ? 67  LEU A CB  1 
ATOM   555  C CG  . LEU A 1 71  ? -18.423 -17.675 24.958  1   21.93  ? 67  LEU A CG  1 
ATOM   556  C CD1 . LEU A 1 71  ? -18.047 -18.26  26.31   1   21.38  ? 67  LEU A CD1 1 
ATOM   557  C CD2 . LEU A 1 71  ? -19.559 -18.456 24.306  1   20.01  ? 67  LEU A CD2 1 
ATOM   558  N N   . ASP A 1 72  ? -18.116 -13.223 23.878  1   19.8   ? 68  ASP A N   1 
ATOM   559  C CA  . ASP A 1 72  ? -18.18  -11.797 24.166  1   20.45  ? 68  ASP A CA  1 
ATOM   560  C C   . ASP A 1 72  ? -16.898 -11.096 23.721  1   20.25  ? 68  ASP A C   1 
ATOM   561  O O   . ASP A 1 72  ? -15.902 -11.764 23.451  1   19.94  ? 68  ASP A O   1 
ATOM   562  C CB  . ASP A 1 72  ? -18.491 -11.528 25.631  1   19.84  ? 68  ASP A CB  1 
ATOM   563  C CG  . ASP A 1 72  ? -19.205 -10.207 25.833  1   21.54  ? 68  ASP A CG  1 
ATOM   564  O OD1 . ASP A 1 72  ? -19.406 -9.487  24.837  1   24.87  ? 68  ASP A OD1 1 
ATOM   565  O OD2 . ASP A 1 72  ? -19.593 -9.925  26.951  1   23.42  ? 68  ASP A OD2 1 
ATOM   566  N N   . VAL A 1 73  ? -16.959 -9.767  23.65   1   19.44  ? 69  VAL A N   1 
ATOM   567  C CA  . VAL A 1 73  ? -15.775 -8.93   23.313  1   19.58  ? 69  VAL A CA  1 
ATOM   568  C C   . VAL A 1 73  ? -15.822 -7.711  24.246  1   21.96  ? 69  VAL A C   1 
ATOM   569  O O   . VAL A 1 73  ? -16.796 -6.953  24.179  1   24.4   ? 69  VAL A O   1 
ATOM   570  C CB  . VAL A 1 73  ? -15.69  -8.494  21.84   1   18.93  ? 69  VAL A CB  1 
ATOM   571  C CG1 . VAL A 1 73  ? -14.619 -7.434  21.627  1   18.75  ? 69  VAL A CG1 1 
ATOM   572  C CG2 . VAL A 1 73  ? -15.452 -9.676  20.913  1   18.42  ? 69  VAL A CG2 1 
ATOM   573  N N   . ILE A 1 74  ? -14.826 -7.575  25.116  1   23.11  ? 70  ILE A N   1 
ATOM   574  C CA  . ILE A 1 74  ? -14.745 -6.397  26.022  1   25.55  ? 70  ILE A CA  1 
ATOM   575  C C   . ILE A 1 74  ? -13.73  -5.427  25.412  1   30.37  ? 70  ILE A C   1 
ATOM   576  O O   . ILE A 1 74  ? -12.641 -5.877  25.037  1   27.16  ? 70  ILE A O   1 
ATOM   577  C CB  . ILE A 1 74  ? -14.391 -6.819  27.458  1   26.6   ? 70  ILE A CB  1 
ATOM   578  C CG1 . ILE A 1 74  ? -15.609 -7.378  28.19   1   27.21  ? 70  ILE A CG1 1 
ATOM   579  C CG2 . ILE A 1 74  ? -13.752 -5.67   28.236  1   26.28  ? 70  ILE A CG2 1 
ATOM   580  C CD1 . ILE A 1 74  ? -15.649 -8.892  28.267  1   26.4   ? 70  ILE A CD1 1 
ATOM   581  N N   . HIS A 1 75  ? -14.104 -4.156  25.292  1   39.98  ? 71  HIS A N   1 
ATOM   582  C CA  . HIS A 1 75  ? -13.227 -3.173  24.613  1   50.09  ? 71  HIS A CA  1 
ATOM   583  C C   . HIS A 1 75  ? -12.885 -2.012  25.531  1   47.28  ? 71  HIS A C   1 
ATOM   584  O O   . HIS A 1 75  ? -13.67  -1.057  25.595  1   54.59  ? 71  HIS A O   1 
ATOM   585  C CB  . HIS A 1 75  ? -13.903 -2.508  23.409  1   58.73  ? 71  HIS A CB  1 
ATOM   586  C CG  . HIS A 1 75  ? -15.092 -3.187  22.828  1   76.29  ? 71  HIS A CG  1 
ATOM   587  N ND1 . HIS A 1 75  ? -16.321 -3.252  23.446  1   100.61 ? 71  HIS A ND1 1 
ATOM   588  C CD2 . HIS A 1 75  ? -15.24  -3.789  21.647  1   78.51  ? 71  HIS A CD2 1 
ATOM   589  C CE1 . HIS A 1 75  ? -17.168 -3.9    22.661  1   101.65 ? 71  HIS A CE1 1 
ATOM   590  N NE2 . HIS A 1 75  ? -16.531 -4.234  21.562  1   86.1   ? 71  HIS A NE2 1 
ATOM   591  N N   . THR A 1 76  ? -11.741 -2.083  26.198  1   53.37  ? 72  THR A N   1 
ATOM   592  C CA  . THR A 1 76  ? -11.288 -0.927  26.99   1   59.27  ? 72  THR A CA  1 
ATOM   593  C C   . THR A 1 76  ? -10.6   0.015   26.018  1   67.6   ? 72  THR A C   1 
ATOM   594  O O   . THR A 1 76  ? -10.598 -0.275  24.806  1   59.42  ? 72  THR A O   1 
ATOM   595  C CB  . THR A 1 76  ? -10.384 -1.401  28.129  1   50.93  ? 72  THR A CB  1 
ATOM   596  O OG1 . THR A 1 76  ? -9.288  -2.082  27.528  1   48.14  ? 72  THR A OG1 1 
ATOM   597  C CG2 . THR A 1 76  ? -11.1   -2.332  29.089  1   50.34  ? 72  THR A CG2 1 
ATOM   598  N N   . GLU A 1 77  ? -10.014 1.099   26.515  1   74.27  ? 73  GLU A N   1 
ATOM   599  C CA  . GLU A 1 77  ? -9.269  2.01    25.614  1   74.55  ? 73  GLU A CA  1 
ATOM   600  C C   . GLU A 1 77  ? -7.883  1.427   25.349  1   63.54  ? 73  GLU A C   1 
ATOM   601  O O   . GLU A 1 77  ? -7.305  1.728   24.284  1   57.69  ? 73  GLU A O   1 
ATOM   602  C CB  . GLU A 1 77  ? -9.13   3.41    26.207  1   94.59  ? 73  GLU A CB  1 
ATOM   603  C CG  . GLU A 1 77  ? -8.873  4.485   25.156  1   118    ? 73  GLU A CG  1 
ATOM   604  C CD  . GLU A 1 77  ? -9.643  4.319   23.856  1   144.54 ? 73  GLU A CD  1 
ATOM   605  O OE1 . GLU A 1 77  ? -9.002  4.033   22.823  1   153.69 ? 73  GLU A OE1 1 
ATOM   606  O OE2 . GLU A 1 77  ? -10.881 4.487   23.873  1   156.76 ? 73  GLU A OE2 1 
ATOM   607  N N   . ASN A 1 78  ? -7.38   0.614   26.273  1   56.07  ? 74  ASN A N   1 
ATOM   608  C CA  . ASN A 1 78  ? -5.991  0.115   26.106  1   51.1   ? 74  ASN A CA  1 
ATOM   609  C C   . ASN A 1 78  ? -6.01   -1.384  25.831  1   45.83  ? 74  ASN A C   1 
ATOM   610  O O   . ASN A 1 78  ? -4.981  -1.911  25.382  1   46.76  ? 74  ASN A O   1 
ATOM   611  C CB  . ASN A 1 78  ? -5.152  0.474   27.323  1   53.34  ? 74  ASN A CB  1 
ATOM   612  C CG  . ASN A 1 78  ? -5.151  1.96    27.582  1   53.2   ? 74  ASN A CG  1 
ATOM   613  O OD1 . ASN A 1 78  ? -5.689  2.414   28.597  1   49.68  ? 74  ASN A OD1 1 
ATOM   614  N ND2 . ASN A 1 78  ? -4.564  2.73    26.679  1   52.34  ? 74  ASN A ND2 1 
ATOM   615  N N   . LYS A 1 79  ? -7.145  -2.034  26.072  1   40.69  ? 75  LYS A N   1 
ATOM   616  C CA  . LYS A 1 79  ? -7.164  -3.508  25.929  1   35.18  ? 75  LYS A CA  1 
ATOM   617  C C   . LYS A 1 79  ? -8.45   -4.032  25.284  1   30.06  ? 75  LYS A C   1 
ATOM   618  O O   . LYS A 1 79  ? -9.497  -3.383  25.394  1   27.96  ? 75  LYS A O   1 
ATOM   619  C CB  . LYS A 1 79  ? -6.967  -4.154  27.301  1   43.06  ? 75  LYS A CB  1 
ATOM   620  C CG  . LYS A 1 79  ? -5.597  -3.93   27.913  1   53.12  ? 75  LYS A CG  1 
ATOM   621  C CD  . LYS A 1 79  ? -5.481  -4.578  29.285  1   54.61  ? 75  LYS A CD  1 
ATOM   622  C CE  . LYS A 1 79  ? -4.125  -4.373  29.867  1   58.43  ? 75  LYS A CE  1 
ATOM   623  N NZ  . LYS A 1 79  ? -4.025  -4.978  31.197  1   64.48  ? 75  LYS A NZ  1 
ATOM   624  N N   . LEU A 1 80  ? -8.335  -5.166  24.613  1   25.56  ? 76  LEU A N   1 
ATOM   625  C CA  . LEU A 1 80  ? -9.485  -5.842  23.978  1   23.92  ? 76  LEU A CA  1 
ATOM   626  C C   . LEU A 1 80  ? -9.486  -7.287  24.471  1   25.23  ? 76  LEU A C   1 
ATOM   627  O O   . LEU A 1 80  ? -8.434  -7.935  24.402  1   26.06  ? 76  LEU A O   1 
ATOM   628  C CB  . LEU A 1 80  ? -9.351  -5.765  22.463  1   24.13  ? 76  LEU A CB  1 
ATOM   629  C CG  . LEU A 1 80  ? -10.642 -5.887  21.653  1   23.1   ? 76  LEU A CG  1 
ATOM   630  C CD1 . LEU A 1 80  ? -11.447 -4.615  21.779  1   22.76  ? 76  LEU A CD1 1 
ATOM   631  C CD2 . LEU A 1 80  ? -10.266 -6.126  20.207  1   22.06  ? 76  LEU A CD2 1 
ATOM   632  N N   . TYR A 1 81  ? -10.629 -7.752  24.962  1   27.64  ? 77  TYR A N   1 
ATOM   633  C CA  . TYR A 1 81  ? -10.708 -9.12   25.528  1   25.75  ? 77  TYR A CA  1 
ATOM   634  C C   . TYR A 1 81  ? -11.725 -9.95   24.796  1   26.57  ? 77  TYR A C   1 
ATOM   635  O O   . TYR A 1 81  ? -12.92  -9.646  24.88   1   28.13  ? 77  TYR A O   1 
ATOM   636  C CB  . TYR A 1 81  ? -11.078 -9.065  27.008  1   27.83  ? 77  TYR A CB  1 
ATOM   637  C CG  . TYR A 1 81  ? -9.967  -8.609  27.938  1   31.41  ? 77  TYR A CG  1 
ATOM   638  C CD1 . TYR A 1 81  ? -8.971  -9.483  28.347  1   34.29  ? 77  TYR A CD1 1 
ATOM   639  C CD2 . TYR A 1 81  ? -9.922  -7.305  28.409  1   32.43  ? 77  TYR A CD2 1 
ATOM   640  C CE1 . TYR A 1 81  ? -7.963  -9.075  29.201  1   35.91  ? 77  TYR A CE1 1 
ATOM   641  C CE2 . TYR A 1 81  ? -8.918  -6.883  29.261  1   34.65  ? 77  TYR A CE2 1 
ATOM   642  C CZ  . TYR A 1 81  ? -7.936  -7.77   29.658  1   37.8   ? 77  TYR A CZ  1 
ATOM   643  O OH  . TYR A 1 81  ? -6.946  -7.355  30.497  1   43.41  ? 77  TYR A OH  1 
ATOM   644  N N   . LEU A 1 82  ? -11.259 -10.948 24.056  1   25.91  ? 78  LEU A N   1 
ATOM   645  C CA  . LEU A 1 82  ? -12.132 -11.914 23.417  1   26.07  ? 78  LEU A CA  1 
ATOM   646  C C   . LEU A 1 82  ? -12.449 -13.012 24.432  1   28.23  ? 78  LEU A C   1 
ATOM   647  O O   . LEU A 1 82  ? -11.534 -13.611 24.972  1   34.8   ? 78  LEU A O   1 
ATOM   648  C CB  . LEU A 1 82  ? -11.441 -12.492 22.181  1   23.95  ? 78  LEU A CB  1 
ATOM   649  C CG  . LEU A 1 82  ? -10.874 -11.497 21.159  1   22.6   ? 78  LEU A CG  1 
ATOM   650  C CD1 . LEU A 1 82  ? -11.102 -12.005 19.753  1   20.63  ? 78  LEU A CD1 1 
ATOM   651  C CD2 . LEU A 1 82  ? -11.428 -10.116 21.312  1   24.07  ? 78  LEU A CD2 1 
ATOM   652  N N   . VAL A 1 83  ? -13.731 -13.268 24.721  1   25.85  ? 79  VAL A N   1 
ATOM   653  C CA  . VAL A 1 83  ? -14.122 -14.347 25.623  1   22.08  ? 79  VAL A CA  1 
ATOM   654  C C   . VAL A 1 83  ? -14.559 -15.548 24.795  1   22.79  ? 79  VAL A C   1 
ATOM   655  O O   . VAL A 1 83  ? -15.524 -15.445 24.041  1   26.23  ? 79  VAL A O   1 
ATOM   656  C CB  . VAL A 1 83  ? -15.289 -13.879 26.504  1   20.31  ? 79  VAL A CB  1 
ATOM   657  C CG1 . VAL A 1 83  ? -15.654 -14.886 27.591  1   19.29  ? 79  VAL A CG1 1 
ATOM   658  C CG2 . VAL A 1 83  ? -14.977 -12.534 27.124  1   20.17  ? 79  VAL A CG2 1 
ATOM   659  N N   . PHE A 1 84  ? -13.873 -16.688 24.949  1   20.47  ? 80  PHE A N   1 
ATOM   660  C CA  . PHE A 1 84  ? -14.22  -17.87  24.176  1   19.88  ? 80  PHE A CA  1 
ATOM   661  C C   . PHE A 1 84  ? -14.714 -18.985 25.088  1   21.68  ? 80  PHE A C   1 
ATOM   662  O O   . PHE A 1 84  ? -14.325 -19.085 26.249  1   27.14  ? 80  PHE A O   1 
ATOM   663  C CB  . PHE A 1 84  ? -13.047 -18.421 23.364  1   20.45  ? 80  PHE A CB  1 
ATOM   664  C CG  . PHE A 1 84  ? -12.503 -17.538 22.26   1   21.61  ? 80  PHE A CG  1 
ATOM   665  C CD1 . PHE A 1 84  ? -11.511 -16.596 22.528  1   21.29  ? 80  PHE A CD1 1 
ATOM   666  C CD2 . PHE A 1 84  ? -12.913 -17.726 20.939  1   22.01  ? 80  PHE A CD2 1 
ATOM   667  C CE1 . PHE A 1 84  ? -10.953 -15.857 21.484  1   22.29  ? 80  PHE A CE1 1 
ATOM   668  C CE2 . PHE A 1 84  ? -12.351 -16.965 19.906  1   22.29  ? 80  PHE A CE2 1 
ATOM   669  C CZ  . PHE A 1 84  ? -11.383 -16.025 20.18   1   19.77  ? 80  PHE A CZ  1 
ATOM   670  N N   . GLU A 1 85  ? -15.571 -19.838 24.534  1   21.44  ? 81  GLU A N   1 
ATOM   671  C CA  . GLU A 1 85  ? -15.814 -21.174 25.055  1   21.24  ? 81  GLU A CA  1 
ATOM   672  C C   . GLU A 1 85  ? -14.47  -21.821 25.352  1   23.63  ? 81  GLU A C   1 
ATOM   673  O O   . GLU A 1 85  ? -13.546 -21.63  24.569  1   24.82  ? 81  GLU A O   1 
ATOM   674  C CB  . GLU A 1 85  ? -16.434 -21.888 23.857  1   22.19  ? 81  GLU A CB  1 
ATOM   675  C CG  . GLU A 1 85  ? -16.596 -23.391 24.007  1   26.5   ? 81  GLU A CG  1 
ATOM   676  C CD  . GLU A 1 85  ? -17.098 -24.067 22.748  1   28.39  ? 81  GLU A CD  1 
ATOM   677  O OE1 . GLU A 1 85  ? -17.543 -25.229 22.904  1   30.52  ? 81  GLU A OE1 1 
ATOM   678  O OE2 . GLU A 1 85  ? -17.038 -23.464 21.645  1   28.4   ? 81  GLU A OE2 1 
ATOM   679  N N   . PHE A 1 86  ? -14.349 -22.552 26.476  1   24.43  ? 82  PHE A N   1 
ATOM   680  C CA  . PHE A 1 86  ? -13.07  -23.14  26.867  1   22.66  ? 82  PHE A CA  1 
ATOM   681  C C   . PHE A 1 86  ? -13.018 -24.611 26.497  1   24.01  ? 82  PHE A C   1 
ATOM   682  O O   . PHE A 1 86  ? -13.938 -25.348 26.827  1   27.73  ? 82  PHE A O   1 
ATOM   683  C CB  . PHE A 1 86  ? -12.833 -23.101 28.378  1   23.2   ? 82  PHE A CB  1 
ATOM   684  C CG  . PHE A 1 86  ? -11.619 -23.884 28.871  1   24     ? 82  PHE A CG  1 
ATOM   685  C CD1 . PHE A 1 86  ? -10.325 -23.383 28.732  1   23.13  ? 82  PHE A CD1 1 
ATOM   686  C CD2 . PHE A 1 86  ? -11.77  -25.134 29.47   1   22.8   ? 82  PHE A CD2 1 
ATOM   687  C CE1 . PHE A 1 86  ? -9.235  -24.118 29.188  1   22.97  ? 82  PHE A CE1 1 
ATOM   688  C CE2 . PHE A 1 86  ? -10.676 -25.851 29.933  1   20.64  ? 82  PHE A CE2 1 
ATOM   689  C CZ  . PHE A 1 86  ? -9.414  -25.346 29.79   1   20.51  ? 82  PHE A CZ  1 
ATOM   690  N N   . LEU A 1 87  ? -11.934 -24.994 25.824  1   25.88  ? 83  LEU A N   1 
ATOM   691  C CA  . LEU A 1 87  ? -11.688 -26.413 25.481  1   26.11  ? 83  LEU A CA  1 
ATOM   692  C C   . LEU A 1 87  ? -10.337 -26.759 26.117  1   28.65  ? 83  LEU A C   1 
ATOM   693  O O   . LEU A 1 87  ? -9.405  -25.953 25.977  1   29     ? 83  LEU A O   1 
ATOM   694  C CB  . LEU A 1 87  ? -11.74  -26.629 23.972  1   24.03  ? 83  LEU A CB  1 
ATOM   695  C CG  . LEU A 1 87  ? -13.139 -26.627 23.352  1   26.93  ? 83  LEU A CG  1 
ATOM   696  C CD1 . LEU A 1 87  ? -13.439 -25.283 22.72   1   26.19  ? 83  LEU A CD1 1 
ATOM   697  C CD2 . LEU A 1 87  ? -13.27  -27.744 22.339  1   27.53  ? 83  LEU A CD2 1 
ATOM   698  N N   . HIS A 1 88  ? -10.236 -27.903 26.782  1   26.44  ? 84  HIS A N   1 
ATOM   699  C CA  . HIS A 1 88  ? -9.018  -28.218 27.578  1   26.15  ? 84  HIS A CA  1 
ATOM   700  C C   . HIS A 1 88  ? -7.759  -28.479 26.75   1   28.65  ? 84  HIS A C   1 
ATOM   701  O O   . HIS A 1 88  ? -6.663  -28.27  27.295  1   27.13  ? 84  HIS A O   1 
ATOM   702  C CB  . HIS A 1 88  ? -9.306  -29.389 28.522  1   24.18  ? 84  HIS A CB  1 
ATOM   703  C CG  . HIS A 1 88  ? -9.227  -30.746 27.916  1   22.84  ? 84  HIS A CG  1 
ATOM   704  N ND1 . HIS A 1 88  ? -8.229  -31.64  28.231  1   21.85  ? 84  HIS A ND1 1 
ATOM   705  C CD2 . HIS A 1 88  ? -10.018 -31.369 27.042  1   23.58  ? 84  HIS A CD2 1 
ATOM   706  C CE1 . HIS A 1 88  ? -8.418  -32.759 27.551  1   22.74  ? 84  HIS A CE1 1 
ATOM   707  N NE2 . HIS A 1 88  ? -9.5    -32.615 26.822  1   23.61  ? 84  HIS A NE2 1 
ATOM   708  N N   . GLN A 1 89  ? -7.885  -28.911 25.5    1   29.03  ? 85  GLN A N   1 
ATOM   709  C CA  . GLN A 1 89  ? -6.636  -29.27  24.794  1   30.58  ? 85  GLN A CA  1 
ATOM   710  C C   . GLN A 1 89  ? -6.7    -29.084 23.284  1   27.82  ? 85  GLN A C   1 
ATOM   711  O O   . GLN A 1 89  ? -7.8    -28.95  22.747  1   26.15  ? 85  GLN A O   1 
ATOM   712  C CB  . GLN A 1 89  ? -6.357  -30.746 25.058  1   34.67  ? 85  GLN A CB  1 
ATOM   713  C CG  . GLN A 1 89  ? -4.883  -31.129 25.008  1   37.15  ? 85  GLN A CG  1 
ATOM   714  C CD  . GLN A 1 89  ? -4.66   -32.61  25.206  1   43.66  ? 85  GLN A CD  1 
ATOM   715  O OE1 . GLN A 1 89  ? -3.556  -33.06  25.525  1   54.35  ? 85  GLN A OE1 1 
ATOM   716  N NE2 . GLN A 1 89  ? -5.718  -33.385 25.03   1   53.62  ? 85  GLN A NE2 1 
ATOM   717  N N   . ASP A 1 90  ? -5.533  -29.048 22.653  1   24.84  ? 86  ASP A N   1 
ATOM   718  C CA  . ASP A 1 90  ? -5.464  -29.021 21.199  1   26.7   ? 86  ASP A CA  1 
ATOM   719  C C   . ASP A 1 90  ? -5.025  -30.389 20.672  1   26.78  ? 86  ASP A C   1 
ATOM   720  O O   . ASP A 1 90  ? -4.483  -31.203 21.415  1   26.27  ? 86  ASP A O   1 
ATOM   721  C CB  . ASP A 1 90  ? -4.621  -27.88  20.654  1   28.21  ? 86  ASP A CB  1 
ATOM   722  C CG  . ASP A 1 90  ? -3.124  -28.048 20.829  1   35.9   ? 86  ASP A CG  1 
ATOM   723  O OD1 . ASP A 1 90  ? -2.588  -29.064 20.363  1   37.9   ? 86  ASP A OD1 1 
ATOM   724  O OD2 . ASP A 1 90  ? -2.496  -27.152 21.412  1   46.93  ? 86  ASP A OD2 1 
ATOM   725  N N   . LEU A 1 91  ? -5.249  -30.626 19.369  1   27.04  ? 87  LEU A N   1 
ATOM   726  C CA  . LEU A 1 91  ? -5.057  -31.94  18.774  1   27.34  ? 87  LEU A CA  1 
ATOM   727  C C   . LEU A 1 91  ? -3.571  -32.314 18.748  1   27.51  ? 87  LEU A C   1 
ATOM   728  O O   . LEU A 1 91  ? -3.211  -33.485 18.912  1   28.81  ? 87  LEU A O   1 
ATOM   729  C CB  . LEU A 1 91  ? -5.671  -31.956 17.38   1   22.86  ? 87  LEU A CB  1 
ATOM   730  C CG  . LEU A 1 91  ? -5.501  -33.266 16.601  1   22.31  ? 87  LEU A CG  1 
ATOM   731  C CD1 . LEU A 1 91  ? -6.367  -34.372 17.17   1   20.64  ? 87  LEU A CD1 1 
ATOM   732  C CD2 . LEU A 1 91  ? -5.802  -33.059 15.124  1   21.81  ? 87  LEU A CD2 1 
ATOM   733  N N   . LYS A 1 92  ? -2.713  -31.311 18.538  1   27.19  ? 88  LYS A N   1 
ATOM   734  C CA  . LYS A 1 92  ? -1.279  -31.551 18.499  1   33     ? 88  LYS A CA  1 
ATOM   735  C C   . LYS A 1 92  ? -0.818  -32.112 19.846  1   34.01  ? 88  LYS A C   1 
ATOM   736  O O   . LYS A 1 92  ? -0.127  -33.136 19.874  1   33.22  ? 88  LYS A O   1 
ATOM   737  C CB  . LYS A 1 92  ? -0.542  -30.303 18.01   1   32.39  ? 88  LYS A CB  1 
ATOM   738  C CG  . LYS A 1 92  ? 0.876   -30.113 18.482  1   31.67  ? 88  LYS A CG  1 
ATOM   739  C CD  . LYS A 1 92  ? 1.842   -31.23  18.142  1   38.43  ? 88  LYS A CD  1 
ATOM   740  C CE  . LYS A 1 92  ? 1.9     -31.594 16.689  1   43.75  ? 88  LYS A CE  1 
ATOM   741  N NZ  . LYS A 1 92  ? 3.075   -32.441 16.48   1   39.88  ? 88  LYS A NZ  1 
ATOM   742  N N   . LYS A 1 93  ? -1.245  -31.47  20.945  1   31.66  ? 89  LYS A N   1 
ATOM   743  C CA  . LYS A 1 93  ? -0.849  -31.891 22.278  1   32.29  ? 89  LYS A CA  1 
ATOM   744  C C   . LYS A 1 93  ? -1.438  -33.259 22.61   1   30.76  ? 89  LYS A C   1 
ATOM   745  O O   . LYS A 1 93  ? -0.824  -34.01  23.356  1   29.94  ? 89  LYS A O   1 
ATOM   746  C CB  . LYS A 1 93  ? -1.134  -30.838 23.352  1   38.22  ? 89  LYS A CB  1 
ATOM   747  C CG  . LYS A 1 93  ? -0.068  -29.747 23.375  1   51.64  ? 89  LYS A CG  1 
ATOM   748  C CD  . LYS A 1 93  ? -0.28   -28.595 24.354  1   59.98  ? 89  LYS A CD  1 
ATOM   749  C CE  . LYS A 1 93  ? 0.528   -27.395 23.937  1   63.24  ? 89  LYS A CE  1 
ATOM   750  N NZ  . LYS A 1 93  ? 0.031   -26.139 24.504  1   68.14  ? 89  LYS A NZ  1 
ATOM   751  N N   . PHE A 1 94  ? -2.618  -33.575 22.061  1   26.95  ? 90  PHE A N   1 
ATOM   752  C CA  . PHE A 1 94  ? -3.244  -34.862 22.322  1   26.99  ? 90  PHE A CA  1 
ATOM   753  C C   . PHE A 1 94  ? -2.468  -35.958 21.596  1   25.93  ? 90  PHE A C   1 
ATOM   754  O O   . PHE A 1 94  ? -2.238  -37.027 22.142  1   27.31  ? 90  PHE A O   1 
ATOM   755  C CB  . PHE A 1 94  ? -4.721  -34.86  21.909  1   26.7   ? 90  PHE A CB  1 
ATOM   756  C CG  . PHE A 1 94  ? -5.418  -36.214 21.96   1   25.63  ? 90  PHE A CG  1 
ATOM   757  C CD1 . PHE A 1 94  ? -5.723  -36.818 23.172  1   25.55  ? 90  PHE A CD1 1 
ATOM   758  C CD2 . PHE A 1 94  ? -5.798  -36.866 20.794  1   25.36  ? 90  PHE A CD2 1 
ATOM   759  C CE1 . PHE A 1 94  ? -6.38   -38.036 23.218  1   25.39  ? 90  PHE A CE1 1 
ATOM   760  C CE2 . PHE A 1 94  ? -6.476  -38.072 20.853  1   26.5   ? 90  PHE A CE2 1 
ATOM   761  C CZ  . PHE A 1 94  ? -6.748  -38.668 22.059  1   26.27  ? 90  PHE A CZ  1 
ATOM   762  N N   . MET A 1 95  ? -2.053  -35.69  20.361  1   26.15  ? 91  MET A N   1 
ATOM   763  C CA  . MET A 1 95  ? -1.24   -36.651 19.636  1   28.09  ? 91  MET A CA  1 
ATOM   764  C C   . MET A 1 95  ? 0.135   -36.879 20.28   1   32.02  ? 91  MET A C   1 
ATOM   765  O O   . MET A 1 95  ? 0.632   -38     20.265  1   33.53  ? 91  MET A O   1 
ATOM   766  C CB  . MET A 1 95  ? -1.12   -36.228 18.18   1   27.7   ? 91  MET A CB  1 
ATOM   767  C CG  . MET A 1 95  ? -2.323  -36.663 17.384  1   28.92  ? 91  MET A CG  1 
ATOM   768  S SD  . MET A 1 95  ? -2.078  -36.09  15.696  1   38.7   ? 91  MET A SD  1 
ATOM   769  C CE  . MET A 1 95  ? -1.774  -34.324 15.892  1   33.8   ? 91  MET A CE  1 
ATOM   770  N N   . ASP A 1 96  ? 0.718   -35.851 20.912  1   29.65  ? 92  ASP A N   1 
ATOM   771  C CA  . ASP A 1 96  ? 2.06    -35.95  21.458  1   32     ? 92  ASP A CA  1 
ATOM   772  C C   . ASP A 1 96  ? 2.084   -36.75  22.752  1   33.68  ? 92  ASP A C   1 
ATOM   773  O O   . ASP A 1 96  ? 2.964   -37.579 22.936  1   36.18  ? 92  ASP A O   1 
ATOM   774  C CB  . ASP A 1 96  ? 2.702   -34.582 21.623  1   32.61  ? 92  ASP A CB  1 
ATOM   775  C CG  . ASP A 1 96  ? 3.169   -33.949 20.32   1   35.27  ? 92  ASP A CG  1 
ATOM   776  O OD1 . ASP A 1 96  ? 3.348   -34.708 19.314  1   33.77  ? 92  ASP A OD1 1 
ATOM   777  O OD2 . ASP A 1 96  ? 3.33    -32.705 20.321  1   36.71  ? 92  ASP A OD2 1 
ATOM   778  N N   . ALA A 1 97  ? 1.106   -36.526 23.634  1   40.46  ? 93  ALA A N   1 
ATOM   779  C CA  . ALA A 1 97  ? 1.187   -37.054 24.986  1   43.66  ? 93  ALA A CA  1 
ATOM   780  C C   . ALA A 1 97  ? 0.371   -38.338 25.185  1   46.55  ? 93  ALA A C   1 
ATOM   781  O O   . ALA A 1 97  ? 0.805   -39.231 25.922  1   56.26  ? 93  ALA A O   1 
ATOM   782  C CB  . ALA A 1 97  ? 0.824   -35.967 25.975  1   39.72  ? 93  ALA A CB  1 
ATOM   783  N N   . SER A 1 98  ? -0.81   -38.431 24.565  1   45.88  ? 94  SER A N   1 
ATOM   784  C CA  . SER A 1 98  ? -1.69   -39.538 24.913  1   50.83  ? 94  SER A CA  1 
ATOM   785  C C   . SER A 1 98  ? -1.78   -40.547 23.78   1   55.2   ? 94  SER A C   1 
ATOM   786  O O   . SER A 1 98  ? -2.175  -41.694 24.011  1   70.12  ? 94  SER A O   1 
ATOM   787  C CB  . SER A 1 98  ? -3.064  -39.1   25.367  1   44.39  ? 94  SER A CB  1 
ATOM   788  O OG  . SER A 1 98  ? -2.965  -38.173 26.435  1   44.04  ? 94  SER A OG  1 
ATOM   789  N N   . ALA A 1 99  ? -1.407  -40.118 22.575  1   45.6   ? 95  ALA A N   1 
ATOM   790  C CA  . ALA A 1 99  ? -1.595  -40.988 21.439  1   40.7   ? 95  ALA A CA  1 
ATOM   791  C C   . ALA A 1 99  ? -0.219  -41.528 21.065  1   51.3   ? 95  ALA A C   1 
ATOM   792  O O   . ALA A 1 99  ? 0.414   -41.063 20.129  1   64.31  ? 95  ALA A O   1 
ATOM   793  C CB  . ALA A 1 99  ? -2.293  -40.214 20.373  1   33.63  ? 95  ALA A CB  1 
ATOM   794  N N   . LEU A 1 100 ? 0.257   -42.494 21.856  1   55.52  ? 96  LEU A N   1 
ATOM   795  C CA  . LEU A 1 100 ? 1.613   -43     21.757  1   54.43  ? 96  LEU A CA  1 
ATOM   796  C C   . LEU A 1 100 ? 1.607   -44.306 20.98   1   58.91  ? 96  LEU A C   1 
ATOM   797  O O   . LEU A 1 100 ? 2.55    -44.594 20.247  1   63.89  ? 96  LEU A O   1 
ATOM   798  C CB  . LEU A 1 100 ? 2.167   -43.222 23.162  1   56.67  ? 96  LEU A CB  1 
ATOM   799  C CG  . LEU A 1 100 ? 2.344   -41.965 24.016  1   58.27  ? 96  LEU A CG  1 
ATOM   800  C CD1 . LEU A 1 100 ? 2.761   -42.318 25.443  1   54.86  ? 96  LEU A CD1 1 
ATOM   801  C CD2 . LEU A 1 100 ? 3.328   -41.012 23.364  1   61.21  ? 96  LEU A CD2 1 
ATOM   802  N N   . THR A 1 101 ? 0.56    -45.108 21.202  1   56.91  ? 97  THR A N   1 
ATOM   803  C CA  . THR A 1 101 ? 0.33    -46.285 20.384  1   50.65  ? 97  THR A CA  1 
ATOM   804  C C   . THR A 1 101 ? -0.81   -45.976 19.41   1   47.58  ? 97  THR A C   1 
ATOM   805  O O   . THR A 1 101 ? -1.376  -46.879 18.791  1   44.69  ? 97  THR A O   1 
ATOM   806  C CB  . THR A 1 101 ? 0.141   -47.511 21.281  1   51.59  ? 97  THR A CB  1 
ATOM   807  O OG1 . THR A 1 101 ? -0.757  -47.137 22.325  1   55.38  ? 97  THR A OG1 1 
ATOM   808  C CG2 . THR A 1 101 ? 1.465   -48.018 21.841  1   43.84  ? 97  THR A CG2 1 
ATOM   809  N N   . GLY A 1 102 ? -1.143  -44.679 19.286  1   42.27  ? 98  GLY A N   1 
ATOM   810  C CA  . GLY A 1 102 ? -2.053  -44.23  18.244  1   37.3   ? 98  GLY A CA  1 
ATOM   811  C C   . GLY A 1 102 ? -3.411  -43.736 18.754  1   37.37  ? 98  GLY A C   1 
ATOM   812  O O   . GLY A 1 102 ? -3.768  -43.864 19.929  1   33.99  ? 98  GLY A O   1 
ATOM   813  N N   . ILE A 1 103 ? -4.145  -43.106 17.836  1   36.32  ? 99  ILE A N   1 
ATOM   814  C CA  . ILE A 1 103 ? -5.538  -42.762 18.052  1   31.82  ? 99  ILE A CA  1 
ATOM   815  C C   . ILE A 1 103 ? -6.366  -43.927 17.527  1   28.8   ? 99  ILE A C   1 
ATOM   816  O O   . ILE A 1 103 ? -6.118  -44.445 16.446  1   31.71  ? 99  ILE A O   1 
ATOM   817  C CB  . ILE A 1 103 ? -5.888  -41.442 17.346  1   33.92  ? 99  ILE A CB  1 
ATOM   818  C CG1 . ILE A 1 103 ? -4.907  -40.328 17.709  1   36.26  ? 99  ILE A CG1 1 
ATOM   819  C CG2 . ILE A 1 103 ? -7.328  -41.029 17.648  1   35.85  ? 99  ILE A CG2 1 
ATOM   820  C CD1 . ILE A 1 103 ? -5.253  -38.977 17.103  1   37.64  ? 99  ILE A CD1 1 
ATOM   821  N N   . PRO A 1 104 ? -7.369  -44.407 18.28   1   27.69  ? 100 PRO A N   1 
ATOM   822  C CA  . PRO A 1 104 ? -8.253  -45.455 17.769  1   26.53  ? 100 PRO A CA  1 
ATOM   823  C C   . PRO A 1 104 ? -8.986  -44.962 16.53   1   24.93  ? 100 PRO A C   1 
ATOM   824  O O   . PRO A 1 104 ? -9.287  -43.779 16.41   1   24.16  ? 100 PRO A O   1 
ATOM   825  C CB  . PRO A 1 104 ? -9.188  -45.735 18.942  1   30.61  ? 100 PRO A CB  1 
ATOM   826  C CG  . PRO A 1 104 ? -8.418  -45.225 20.156  1   30.51  ? 100 PRO A CG  1 
ATOM   827  C CD  . PRO A 1 104 ? -7.687  -43.987 19.651  1   28.05  ? 100 PRO A CD  1 
ATOM   828  N N   . LEU A 1 105 ? -9.21   -45.891 15.594  1   28.21  ? 101 LEU A N   1 
ATOM   829  C CA  . LEU A 1 105 ? -9.878  -45.635 14.326  1   27.98  ? 101 LEU A CA  1 
ATOM   830  C C   . LEU A 1 105 ? -11.232 -44.973 14.56   1   27.04  ? 101 LEU A C   1 
ATOM   831  O O   . LEU A 1 105 ? -11.55  -44.009 13.887  1   29.93  ? 101 LEU A O   1 
ATOM   832  C CB  . LEU A 1 105 ? -10.059 -46.941 13.561  1   27.98  ? 101 LEU A CB  1 
ATOM   833  C CG  . LEU A 1 105 ? -10.816 -46.828 12.234  1   29.65  ? 101 LEU A CG  1 
ATOM   834  C CD1 . LEU A 1 105 ? -10.012 -45.943 11.3    1   31.47  ? 101 LEU A CD1 1 
ATOM   835  C CD2 . LEU A 1 105 ? -11.201 -48.144 11.566  1   27.49  ? 101 LEU A CD2 1 
ATOM   836  N N   . PRO A 1 106 ? -12.065 -45.443 15.52   1   27.24  ? 102 PRO A N   1 
ATOM   837  C CA  . PRO A 1 106 ? -13.302 -44.748 15.892  1   25.95  ? 102 PRO A CA  1 
ATOM   838  C C   . PRO A 1 106 ? -13.182 -43.257 16.166  1   26.74  ? 102 PRO A C   1 
ATOM   839  O O   . PRO A 1 106 ? -14.036 -42.495 15.706  1   26.24  ? 102 PRO A O   1 
ATOM   840  C CB  . PRO A 1 106 ? -13.787 -45.517 17.136  1   24.8   ? 102 PRO A CB  1 
ATOM   841  C CG  . PRO A 1 106 ? -13.292 -46.926 16.884  1   25.42  ? 102 PRO A CG  1 
ATOM   842  C CD  . PRO A 1 106 ? -11.908 -46.701 16.271  1   25.46  ? 102 PRO A CD  1 
ATOM   843  N N   . LEU A 1 107 ? -12.125 -42.857 16.9    1   25.84  ? 103 LEU A N   1 
ATOM   844  C CA  . LEU A 1 107 ? -11.951 -41.487 17.359  1   22.57  ? 103 LEU A CA  1 
ATOM   845  C C   . LEU A 1 107 ? -11.435 -40.61  16.228  1   24.12  ? 103 LEU A C   1 
ATOM   846  O O   . LEU A 1 107 ? -11.788 -39.439 16.15   1   25.61  ? 103 LEU A O   1 
ATOM   847  C CB  . LEU A 1 107 ? -10.993 -41.487 18.542  1   23.6   ? 103 LEU A CB  1 
ATOM   848  C CG  . LEU A 1 107 ? -10.85  -40.188 19.351  1   25.32  ? 103 LEU A CG  1 
ATOM   849  C CD1 . LEU A 1 107 ? -12.194 -39.614 19.77   1   23.19  ? 103 LEU A CD1 1 
ATOM   850  C CD2 . LEU A 1 107 ? -10.03  -40.515 20.62   1   23.83  ? 103 LEU A CD2 1 
ATOM   851  N N   . ILE A 1 108 ? -10.601 -41.185 15.352  1   25.22  ? 104 ILE A N   1 
ATOM   852  C CA  . ILE A 1 108 ? -10.061 -40.474 14.202  1   26.69  ? 104 ILE A CA  1 
ATOM   853  C C   . ILE A 1 108 ? -11.217 -40.138 13.257  1   26.16  ? 104 ILE A C   1 
ATOM   854  O O   . ILE A 1 108 ? -11.325 -39.028 12.713  1   25.9   ? 104 ILE A O   1 
ATOM   855  C CB  . ILE A 1 108 ? -9.03   -41.368 13.484  1   27.93  ? 104 ILE A CB  1 
ATOM   856  C CG1 . ILE A 1 108 ? -7.748  -41.566 14.305  1   26.33  ? 104 ILE A CG1 1 
ATOM   857  C CG2 . ILE A 1 108 ? -8.74   -40.856 12.067  1   25.88  ? 104 ILE A CG2 1 
ATOM   858  C CD1 . ILE A 1 108 ? -6.707  -42.44  13.611  1   22.68  ? 104 ILE A CD1 1 
ATOM   859  N N   . LYS A 1 109 ? -12.061 -41.148 13.05   1   22.24  ? 105 LYS A N   1 
ATOM   860  C CA  . LYS A 1 109 ? -13.238 -41.049 12.199  1   23.61  ? 105 LYS A CA  1 
ATOM   861  C C   . LYS A 1 109 ? -14.176 -39.962 12.725  1   22.77  ? 105 LYS A C   1 
ATOM   862  O O   . LYS A 1 109 ? -14.616 -39.106 11.97   1   19.87  ? 105 LYS A O   1 
ATOM   863  C CB  . LYS A 1 109 ? -13.856 -42.449 12.165  1   21.98  ? 105 LYS A CB  1 
ATOM   864  C CG  . LYS A 1 109 ? -14.559 -42.819 10.912  1   24.65  ? 105 LYS A CG  1 
ATOM   865  C CD  . LYS A 1 109 ? -14.884 -44.302 10.985  1   29.8   ? 105 LYS A CD  1 
ATOM   866  C CE  . LYS A 1 109 ? -13.787 -45.149 10.433  1   29.69  ? 105 LYS A CE  1 
ATOM   867  N NZ  . LYS A 1 109 ? -14.303 -46.5   10.188  1   28.94  ? 105 LYS A NZ  1 
ATOM   868  N N   . SER A 1 110 ? -14.39  -39.949 14.05   1   26.53  ? 106 SER A N   1 
ATOM   869  C CA  . SER A 1 110 ? -15.252 -38.97  14.699  1   28.94  ? 106 SER A CA  1 
ATOM   870  C C   . SER A 1 110 ? -14.708 -37.554 14.553  1   26.49  ? 106 SER A C   1 
ATOM   871  O O   . SER A 1 110 ? -15.451 -36.624 14.237  1   23.3   ? 106 SER A O   1 
ATOM   872  C CB  . SER A 1 110 ? -15.497 -39.308 16.146  1   29.66  ? 106 SER A CB  1 
ATOM   873  O OG  . SER A 1 110 ? -15.92  -38.135 16.831  1   35.79  ? 106 SER A OG  1 
ATOM   874  N N   . TYR A 1 111 ? -13.411 -37.404 14.831  1   27.39  ? 107 TYR A N   1 
ATOM   875  C CA  . TYR A 1 111 ? -12.753 -36.108 14.758  1   28.91  ? 107 TYR A CA  1 
ATOM   876  C C   . TYR A 1 111 ? -12.799 -35.567 13.33   1   29.59  ? 107 TYR A C   1 
ATOM   877  O O   . TYR A 1 111 ? -13.145 -34.404 13.117  1   31.21  ? 107 TYR A O   1 
ATOM   878  C CB  . TYR A 1 111 ? -11.306 -36.249 15.234  1   29.76  ? 107 TYR A CB  1 
ATOM   879  C CG  . TYR A 1 111 ? -11.107 -36.226 16.745  1   32.47  ? 107 TYR A CG  1 
ATOM   880  C CD1 . TYR A 1 111 ? -12.193 -36.05  17.611  1   29.9   ? 107 TYR A CD1 1 
ATOM   881  C CD2 . TYR A 1 111 ? -9.83   -36.363 17.299  1   30.32  ? 107 TYR A CD2 1 
ATOM   882  C CE1 . TYR A 1 111 ? -12.009 -36.012 18.982  1   30.67  ? 107 TYR A CE1 1 
ATOM   883  C CE2 . TYR A 1 111 ? -9.639  -36.344 18.672  1   29.01  ? 107 TYR A CE2 1 
ATOM   884  C CZ  . TYR A 1 111 ? -10.732 -36.156 19.502  1   31.79  ? 107 TYR A CZ  1 
ATOM   885  O OH  . TYR A 1 111 ? -10.599 -36.101 20.847  1   38.07  ? 107 TYR A OH  1 
ATOM   886  N N   . LEU A 1 112 ? -12.468 -36.431 12.364  1   27.29  ? 108 LEU A N   1 
ATOM   887  C CA  . LEU A 1 112 ? -12.455 -36.022 10.972  1   27.73  ? 108 LEU A CA  1 
ATOM   888  C C   . LEU A 1 112 ? -13.855 -35.56  10.544  1   28.22  ? 108 LEU A C   1 
ATOM   889  O O   . LEU A 1 112 ? -14.004 -34.52  9.876   1   29.78  ? 108 LEU A O   1 
ATOM   890  C CB  . LEU A 1 112 ? -11.873 -37.109 10.066  1   24.02  ? 108 LEU A CB  1 
ATOM   891  C CG  . LEU A 1 112 ? -11.681 -36.693 8.604   1   20.33  ? 108 LEU A CG  1 
ATOM   892  C CD1 . LEU A 1 112 ? -10.889 -35.385 8.541   1   18.6   ? 108 LEU A CD1 1 
ATOM   893  C CD2 . LEU A 1 112 ? -11.041 -37.763 7.754   1   16.19  ? 108 LEU A CD2 1 
ATOM   894  N N   . PHE A 1 113 ? -14.875 -36.334 10.936  1   26.28  ? 109 PHE A N   1 
ATOM   895  C CA  . PHE A 1 113 ? -16.253 -36.027 10.57   1   27.09  ? 109 PHE A CA  1 
ATOM   896  C C   . PHE A 1 113 ? -16.684 -34.678 11.148  1   28.29  ? 109 PHE A C   1 
ATOM   897  O O   . PHE A 1 113 ? -17.289 -33.869 10.446  1   29.74  ? 109 PHE A O   1 
ATOM   898  C CB  . PHE A 1 113 ? -17.17  -37.138 11.06   1   27.81  ? 109 PHE A CB  1 
ATOM   899  C CG  . PHE A 1 113 ? -18.577 -37.12  10.486  1   28.46  ? 109 PHE A CG  1 
ATOM   900  C CD1 . PHE A 1 113 ? -18.804 -37.312 9.135   1   25.72  ? 109 PHE A CD1 1 
ATOM   901  C CD2 . PHE A 1 113 ? -19.675 -37.007 11.323  1   30.01  ? 109 PHE A CD2 1 
ATOM   902  C CE1 . PHE A 1 113 ? -20.086 -37.346 8.647   1   25.96  ? 109 PHE A CE1 1 
ATOM   903  C CE2 . PHE A 1 113 ? -20.958 -37.092 10.827  1   27.77  ? 109 PHE A CE2 1 
ATOM   904  C CZ  . PHE A 1 113 ? -21.161 -37.234 9.491   1   26.12  ? 109 PHE A CZ  1 
ATOM   905  N N   . GLN A 1 114 ? -16.295 -34.391 12.399  1   28.7   ? 110 GLN A N   1 
ATOM   906  C CA  . GLN A 1 114 ? -16.641 -33.125 13.034  1   26.21  ? 110 GLN A CA  1 
ATOM   907  C C   . GLN A 1 114 ? -15.877 -31.959 12.4    1   28.41  ? 110 GLN A C   1 
ATOM   908  O O   . GLN A 1 114 ? -16.462 -30.89  12.198  1   27.22  ? 110 GLN A O   1 
ATOM   909  C CB  . GLN A 1 114 ? -16.341 -33.165 14.525  1   23.58  ? 110 GLN A CB  1 
ATOM   910  C CG  . GLN A 1 114 ? -17.255 -34.067 15.339  1   23.73  ? 110 GLN A CG  1 
ATOM   911  C CD  . GLN A 1 114 ? -16.83  -34.048 16.79   1   26.22  ? 110 GLN A CD  1 
ATOM   912  O OE1 . GLN A 1 114 ? -16.946 -33.02  17.471  1   27.21  ? 110 GLN A OE1 1 
ATOM   913  N NE2 . GLN A 1 114 ? -16.251 -35.154 17.254  1   25.87  ? 110 GLN A NE2 1 
ATOM   914  N N   . LEU A 1 115 ? -14.576 -32.156 12.108  1   25.38  ? 111 LEU A N   1 
ATOM   915  C CA  . LEU A 1 115 ? -13.793 -31.13  11.43   1   24.83  ? 111 LEU A CA  1 
ATOM   916  C C   . LEU A 1 115 ? -14.429 -30.775 10.081  1   25.18  ? 111 LEU A C   1 
ATOM   917  O O   . LEU A 1 115 ? -14.487 -29.604 9.695   1   23.93  ? 111 LEU A O   1 
ATOM   918  C CB  . LEU A 1 115 ? -12.357 -31.602 11.232  1   24.66  ? 111 LEU A CB  1 
ATOM   919  C CG  . LEU A 1 115 ? -11.538 -31.731 12.518  1   27.95  ? 111 LEU A CG  1 
ATOM   920  C CD1 . LEU A 1 115 ? -10.202 -32.395 12.252  1   29.24  ? 111 LEU A CD1 1 
ATOM   921  C CD2 . LEU A 1 115 ? -11.329 -30.373 13.16   1   27.33  ? 111 LEU A CD2 1 
ATOM   922  N N   . LEU A 1 116 ? -14.912 -31.784 9.35    1   25     ? 112 LEU A N   1 
ATOM   923  C CA  . LEU A 1 116 ? -15.564 -31.531 8.064   1   24.79  ? 112 LEU A CA  1 
ATOM   924  C C   . LEU A 1 116 ? -16.864 -30.743 8.236   1   24.78  ? 112 LEU A C   1 
ATOM   925  O O   . LEU A 1 116 ? -17.141 -29.835 7.447   1   25.95  ? 112 LEU A O   1 
ATOM   926  C CB  . LEU A 1 116 ? -15.764 -32.846 7.315   1   24.56  ? 112 LEU A CB  1 
ATOM   927  C CG  . LEU A 1 116 ? -14.463 -33.401 6.732   1   25.61  ? 112 LEU A CG  1 
ATOM   928  C CD1 . LEU A 1 116 ? -14.533 -34.896 6.568   1   26.2   ? 112 LEU A CD1 1 
ATOM   929  C CD2 . LEU A 1 116 ? -14.129 -32.689 5.43    1   28.4   ? 112 LEU A CD2 1 
ATOM   930  N N   . GLN A 1 117 ? -17.62  -31.045 9.3     1   22.62  ? 113 GLN A N   1 
ATOM   931  C CA  . GLN A 1 117 ? -18.853 -30.32  9.573   1   24.43  ? 113 GLN A CA  1 
ATOM   932  C C   . GLN A 1 117 ? -18.543 -28.851 9.816   1   25.02  ? 113 GLN A C   1 
ATOM   933  O O   . GLN A 1 117 ? -19.194 -27.959 9.278   1   25.16  ? 113 GLN A O   1 
ATOM   934  C CB  . GLN A 1 117 ? -19.585 -30.861 10.802  1   23.89  ? 113 GLN A CB  1 
ATOM   935  C CG  . GLN A 1 117 ? -20.049 -32.3   10.623  1   22.57  ? 113 GLN A CG  1 
ATOM   936  C CD  . GLN A 1 117 ? -20.928 -32.759 11.76   1   24.86  ? 113 GLN A CD  1 
ATOM   937  O OE1 . GLN A 1 117 ? -21.863 -32.081 12.197  1   24.36  ? 113 GLN A OE1 1 
ATOM   938  N NE2 . GLN A 1 117 ? -20.644 -33.952 12.236  1   27.69  ? 113 GLN A NE2 1 
ATOM   939  N N   . GLY A 1 118 ? -17.532 -28.616 10.647  1   28.97  ? 114 GLY A N   1 
ATOM   940  C CA  . GLY A 1 118 ? -17.096 -27.266 10.963  1   28.14  ? 114 GLY A CA  1 
ATOM   941  C C   . GLY A 1 118 ? -16.656 -26.522 9.709   1   24.36  ? 114 GLY A C   1 
ATOM   942  O O   . GLY A 1 118 ? -17.02  -25.366 9.495   1   23.24  ? 114 GLY A O   1 
ATOM   943  N N   . LEU A 1 119 ? -15.88  -27.205 8.876   1   24.84  ? 115 LEU A N   1 
ATOM   944  C CA  . LEU A 1 119 ? -15.289 -26.551 7.725   1   25.47  ? 115 LEU A CA  1 
ATOM   945  C C   . LEU A 1 119 ? -16.378 -26.287 6.684   1   26.5   ? 115 LEU A C   1 
ATOM   946  O O   . LEU A 1 119 ? -16.417 -25.208 6.08    1   31.31  ? 115 LEU A O   1 
ATOM   947  C CB  . LEU A 1 119 ? -14.14  -27.406 7.201   1   25.4   ? 115 LEU A CB  1 
ATOM   948  C CG  . LEU A 1 119 ? -13.431 -26.821 5.984   1   28.06  ? 115 LEU A CG  1 
ATOM   949  C CD1 . LEU A 1 119 ? -12.959 -25.416 6.338   1   27.61  ? 115 LEU A CD1 1 
ATOM   950  C CD2 . LEU A 1 119 ? -12.283 -27.709 5.559   1   29.99  ? 115 LEU A CD2 1 
ATOM   951  N N   . ALA A 1 120 ? -17.279 -27.257 6.492   1   22.52  ? 116 ALA A N   1 
ATOM   952  C CA  . ALA A 1 120 ? -18.407 -27.058 5.589   1   23.68  ? 116 ALA A CA  1 
ATOM   953  C C   . ALA A 1 120 ? -19.214 -25.809 5.999   1   24.54  ? 116 ALA A C   1 
ATOM   954  O O   . ALA A 1 120 ? -19.605 -24.984 5.176   1   23.62  ? 116 ALA A O   1 
ATOM   955  C CB  . ALA A 1 120 ? -19.24  -28.328 5.532   1   19.21  ? 116 ALA A CB  1 
ATOM   956  N N   . PHE A 1 121 ? -19.418 -25.623 7.305   1   24.74  ? 117 PHE A N   1 
ATOM   957  C CA  . PHE A 1 121 ? -20.112 -24.45  7.807   1   24.14  ? 117 PHE A CA  1 
ATOM   958  C C   . PHE A 1 121 ? -19.35  -23.167 7.463   1   25.11  ? 117 PHE A C   1 
ATOM   959  O O   . PHE A 1 121 ? -19.972 -22.181 7.083   1   25.87  ? 117 PHE A O   1 
ATOM   960  C CB  . PHE A 1 121 ? -20.356 -24.605 9.309   1   22.48  ? 117 PHE A CB  1 
ATOM   961  C CG  . PHE A 1 121 ? -21.298 -23.537 9.836   1   23.38  ? 117 PHE A CG  1 
ATOM   962  C CD1 . PHE A 1 121 ? -20.818 -22.272 10.182  1   20.67  ? 117 PHE A CD1 1 
ATOM   963  C CD2 . PHE A 1 121 ? -22.67  -23.783 9.933   1   22.68  ? 117 PHE A CD2 1 
ATOM   964  C CE1 . PHE A 1 121 ? -21.685 -21.291 10.628  1   21.63  ? 117 PHE A CE1 1 
ATOM   965  C CE2 . PHE A 1 121 ? -23.539 -22.799 10.398  1   20.44  ? 117 PHE A CE2 1 
ATOM   966  C CZ  . PHE A 1 121 ? -23.054 -21.558 10.754  1   21.19  ? 117 PHE A CZ  1 
ATOM   967  N N   . CYS A 1 122 ? -18.011 -23.179 7.578   1   25.03  ? 118 CYS A N   1 
ATOM   968  C CA  . CYS A 1 122 ? -17.229 -21.999 7.236   1   24.8   ? 118 CYS A CA  1 
ATOM   969  C C   . CYS A 1 122 ? -17.414 -21.633 5.758   1   23.57  ? 118 CYS A C   1 
ATOM   970  O O   . CYS A 1 122 ? -17.593 -20.469 5.407   1   23.03  ? 118 CYS A O   1 
ATOM   971  C CB  . CYS A 1 122 ? -15.741 -22.204 7.514   1   23.02  ? 118 CYS A CB  1 
ATOM   972  S SG  . CYS A 1 122 ? -15.344 -22.276 9.282   1   28.82  ? 118 CYS A SG  1 
ATOM   973  N N   . HIS A 1 123 ? -17.295 -22.63  4.885   1   22.63  ? 119 HIS A N   1 
ATOM   974  C CA  . HIS A 1 123 ? -17.369 -22.384 3.459   1   23.5   ? 119 HIS A CA  1 
ATOM   975  C C   . HIS A 1 123 ? -18.776 -21.942 3.066   1   24.55  ? 119 HIS A C   1 
ATOM   976  O O   . HIS A 1 123 ? -18.919 -21.053 2.233   1   27.74  ? 119 HIS A O   1 
ATOM   977  C CB  . HIS A 1 123 ? -16.87  -23.613 2.697   1   23.89  ? 119 HIS A CB  1 
ATOM   978  C CG  . HIS A 1 123 ? -15.435 -23.895 2.968   1   24.59  ? 119 HIS A CG  1 
ATOM   979  N ND1 . HIS A 1 123 ? -14.833 -25.105 2.68    1   24.46  ? 119 HIS A ND1 1 
ATOM   980  C CD2 . HIS A 1 123 ? -14.48  -23.099 3.508   1   24.04  ? 119 HIS A CD2 1 
ATOM   981  C CE1 . HIS A 1 123 ? -13.545 -25.028 3.044   1   28.18  ? 119 HIS A CE1 1 
ATOM   982  N NE2 . HIS A 1 123 ? -13.307 -23.818 3.553   1   26.36  ? 119 HIS A NE2 1 
ATOM   983  N N   . SER A 1 124 ? -19.795 -22.546 3.682   1   22.19  ? 120 SER A N   1 
ATOM   984  C CA  . SER A 1 124 ? -21.179 -22.158 3.466   1   24.2   ? 120 SER A CA  1 
ATOM   985  C C   . SER A 1 124 ? -21.44  -20.715 3.89    1   23.81  ? 120 SER A C   1 
ATOM   986  O O   . SER A 1 124 ? -22.444 -20.143 3.468   1   23.26  ? 120 SER A O   1 
ATOM   987  C CB  . SER A 1 124 ? -22.129 -23.069 4.188   1   24.79  ? 120 SER A CB  1 
ATOM   988  O OG  . SER A 1 124 ? -21.984 -24.396 3.717   1   25.28  ? 120 SER A OG  1 
ATOM   989  N N   . HIS A 1 125 ? -20.585 -20.168 4.763   1   22.21  ? 121 HIS A N   1 
ATOM   990  C CA  . HIS A 1 125 ? -20.705 -18.787 5.209   1   23.08  ? 121 HIS A CA  1 
ATOM   991  C C   . HIS A 1 125 ? -19.544 -17.937 4.69    1   23.9   ? 121 HIS A C   1 
ATOM   992  O O   . HIS A 1 125 ? -19.156 -16.958 5.314   1   25.49  ? 121 HIS A O   1 
ATOM   993  C CB  . HIS A 1 125 ? -20.795 -18.745 6.733   1   22.78  ? 121 HIS A CB  1 
ATOM   994  C CG  . HIS A 1 125 ? -22.048 -19.392 7.181   1   24.57  ? 121 HIS A CG  1 
ATOM   995  N ND1 . HIS A 1 125 ? -22.256 -20.754 7.125   1   24.66  ? 121 HIS A ND1 1 
ATOM   996  C CD2 . HIS A 1 125 ? -23.177 -18.861 7.614   1   25.24  ? 121 HIS A CD2 1 
ATOM   997  C CE1 . HIS A 1 125 ? -23.477 -21.015 7.537   1   24.48  ? 121 HIS A CE1 1 
ATOM   998  N NE2 . HIS A 1 125 ? -24.058 -19.879 7.821   1   25.09  ? 121 HIS A NE2 1 
ATOM   999  N N   . ARG A 1 126 ? -19.026 -18.309 3.521   1   22.36  ? 122 ARG A N   1 
ATOM   1000 C CA  . ARG A 1 126 ? -17.994 -17.587 2.792   1   22.57  ? 122 ARG A CA  1 
ATOM   1001 C C   . ARG A 1 126 ? -16.786 -17.196 3.656   1   22.44  ? 122 ARG A C   1 
ATOM   1002 O O   . ARG A 1 126 ? -16.239 -16.11  3.463   1   21.05  ? 122 ARG A O   1 
ATOM   1003 C CB  . ARG A 1 126 ? -18.636 -16.448 2.002   1   20.98  ? 122 ARG A CB  1 
ATOM   1004 C CG  . ARG A 1 126 ? -19.431 -15.469 2.85    1   20.97  ? 122 ARG A CG  1 
ATOM   1005 C CD  . ARG A 1 126 ? -18.589 -14.283 3.199   1   23.19  ? 122 ARG A CD  1 
ATOM   1006 N NE  . ARG A 1 126 ? -19.312 -13.232 3.925   1   31.03  ? 122 ARG A NE  1 
ATOM   1007 C CZ  . ARG A 1 126 ? -19.707 -13.279 5.212   1   31.66  ? 122 ARG A CZ  1 
ATOM   1008 N NH1 . ARG A 1 126 ? -19.525 -14.377 5.939   1   29     ? 122 ARG A NH1 1 
ATOM   1009 N NH2 . ARG A 1 126 ? -20.27  -12.207 5.753   1   28.76  ? 122 ARG A NH2 1 
ATOM   1010 N N   . VAL A 1 127 ? -16.308 -18.118 4.515   1   22.39  ? 123 VAL A N   1 
ATOM   1011 C CA  . VAL A 1 127 ? -15.093 -17.948 5.309   1   24.55  ? 123 VAL A CA  1 
ATOM   1012 C C   . VAL A 1 127 ? -14.078 -19.05  4.954   1   26.49  ? 123 VAL A C   1 
ATOM   1013 O O   . VAL A 1 127 ? -14.371 -20.245 5.061   1   27.83  ? 123 VAL A O   1 
ATOM   1014 C CB  . VAL A 1 127 ? -15.431 -17.899 6.821   1   25.37  ? 123 VAL A CB  1 
ATOM   1015 C CG1 . VAL A 1 127 ? -14.185 -17.93  7.732   1   20.67  ? 123 VAL A CG1 1 
ATOM   1016 C CG2 . VAL A 1 127 ? -16.319 -16.7   7.158   1   20.46  ? 123 VAL A CG2 1 
ATOM   1017 N N   . LEU A 1 128 ? -12.899 -18.653 4.469   1   22.45  ? 124 LEU A N   1 
ATOM   1018 C CA  . LEU A 1 128 ? -11.742 -19.536 4.437   1   23.81  ? 124 LEU A CA  1 
ATOM   1019 C C   . LEU A 1 128 ? -11.046 -19.491 5.804   1   24.39  ? 124 LEU A C   1 
ATOM   1020 O O   . LEU A 1 128 ? -10.792 -18.406 6.336   1   27.87  ? 124 LEU A O   1 
ATOM   1021 C CB  . LEU A 1 128 ? -10.755 -19.069 3.349   1   22.24  ? 124 LEU A CB  1 
ATOM   1022 C CG  . LEU A 1 128 ? -11.212 -19.184 1.892   1   22.41  ? 124 LEU A CG  1 
ATOM   1023 C CD1 . LEU A 1 128 ? -10.149 -18.691 0.933   1   22.46  ? 124 LEU A CD1 1 
ATOM   1024 C CD2 . LEU A 1 128 ? -11.558 -20.616 1.54    1   21.88  ? 124 LEU A CD2 1 
ATOM   1025 N N   . HIS A 1 129 ? -10.63  -20.651 6.325   1   22.76  ? 125 HIS A N   1 
ATOM   1026 C CA  . HIS A 1 129 ? -9.86   -20.68  7.558   1   23.22  ? 125 HIS A CA  1 
ATOM   1027 C C   . HIS A 1 129 ? -8.4    -20.27  7.334   1   26.48  ? 125 HIS A C   1 
ATOM   1028 O O   . HIS A 1 129 ? -7.978  -19.272 7.896   1   29.3   ? 125 HIS A O   1 
ATOM   1029 C CB  . HIS A 1 129 ? -10.008 -22.011 8.29    1   22.14  ? 125 HIS A CB  1 
ATOM   1030 C CG  . HIS A 1 129 ? -9.428  -21.962 9.656   1   27.6   ? 125 HIS A CG  1 
ATOM   1031 N ND1 . HIS A 1 129 ? -8.059  -22.012 9.848   1   28.11  ? 125 HIS A ND1 1 
ATOM   1032 C CD2 . HIS A 1 129 ? -9.984  -21.833 10.884  1   26.79  ? 125 HIS A CD2 1 
ATOM   1033 C CE1 . HIS A 1 129 ? -7.797  -21.943 11.152  1   28.94  ? 125 HIS A CE1 1 
ATOM   1034 N NE2 . HIS A 1 129 ? -8.957  -21.832 11.802  1   29.57  ? 125 HIS A NE2 1 
ATOM   1035 N N   . ARG A 1 130 ? -7.617  -21.065 6.58    1   25.55  ? 126 ARG A N   1 
ATOM   1036 C CA  . ARG A 1 130 ? -6.318  -20.658 6.038   1   25.76  ? 126 ARG A CA  1 
ATOM   1037 C C   . ARG A 1 130 ? -5.169  -20.928 7.01    1   25.14  ? 126 ARG A C   1 
ATOM   1038 O O   . ARG A 1 130 ? -4.072  -20.403 6.85    1   34.27  ? 126 ARG A O   1 
ATOM   1039 C CB  . ARG A 1 130 ? -6.3    -19.226 5.481   1   22.63  ? 126 ARG A CB  1 
ATOM   1040 C CG  . ARG A 1 130 ? -7.297  -18.998 4.347   1   22.25  ? 126 ARG A CG  1 
ATOM   1041 C CD  . ARG A 1 130 ? -7.024  -17.726 3.549   1   22.4   ? 126 ARG A CD  1 
ATOM   1042 N NE  . ARG A 1 130 ? -6.947  -16.593 4.473   1   23.13  ? 126 ARG A NE  1 
ATOM   1043 C CZ  . ARG A 1 130 ? -6.527  -15.38  4.196   1   24.17  ? 126 ARG A CZ  1 
ATOM   1044 N NH1 . ARG A 1 130 ? -6.021  -15.098 3.016   1   23.09  ? 126 ARG A NH1 1 
ATOM   1045 N NH2 . ARG A 1 130 ? -6.601  -14.447 5.121   1   24.05  ? 126 ARG A NH2 1 
ATOM   1046 N N   . ASP A 1 131 ? -5.418  -21.754 8.016   1   24.24  ? 127 ASP A N   1 
ATOM   1047 C CA  . ASP A 1 131 ? -4.45   -22.099 9.034   1   24.56  ? 127 ASP A CA  1 
ATOM   1048 C C   . ASP A 1 131 ? -4.935  -23.339 9.776   1   25.5   ? 127 ASP A C   1 
ATOM   1049 O O   . ASP A 1 131 ? -4.862  -23.41  11.005  1   28.95  ? 127 ASP A O   1 
ATOM   1050 C CB  . ASP A 1 131 ? -4.141  -20.962 10      1   26.25  ? 127 ASP A CB  1 
ATOM   1051 C CG  . ASP A 1 131 ? -2.7    -21.028 10.508  1   31.58  ? 127 ASP A CG  1 
ATOM   1052 O OD1 . ASP A 1 131 ? -1.871  -21.69  9.853   1   30.38  ? 127 ASP A OD1 1 
ATOM   1053 O OD2 . ASP A 1 131 ? -2.415  -20.494 11.58   1   39.14  ? 127 ASP A OD2 1 
ATOM   1054 N N   . LEU A 1 132 ? -5.429  -24.319 9.018   1   24.54  ? 128 LEU A N   1 
ATOM   1055 C CA  . LEU A 1 132 ? -5.861  -25.544 9.661   1   26.88  ? 128 LEU A CA  1 
ATOM   1056 C C   . LEU A 1 132 ? -4.64   -26.415 9.92    1   28     ? 128 LEU A C   1 
ATOM   1057 O O   . LEU A 1 132 ? -3.894  -26.774 9.004   1   28.49  ? 128 LEU A O   1 
ATOM   1058 C CB  . LEU A 1 132 ? -6.94   -26.237 8.831   1   27.6   ? 128 LEU A CB  1 
ATOM   1059 C CG  . LEU A 1 132 ? -8.275  -25.49  8.762   1   27.66  ? 128 LEU A CG  1 
ATOM   1060 C CD1 . LEU A 1 132 ? -9.118  -26.088 7.645   1   27.65  ? 128 LEU A CD1 1 
ATOM   1061 C CD2 . LEU A 1 132 ? -9.01   -25.543 10.098  1   25.25  ? 128 LEU A CD2 1 
ATOM   1062 N N   . LYS A 1 133 ? -4.433  -26.694 11.203  1   24.72  ? 129 LYS A N   1 
ATOM   1063 C CA  . LYS A 1 133 ? -3.317  -27.507 11.636  1   26.43  ? 129 LYS A CA  1 
ATOM   1064 C C   . LYS A 1 133 ? -3.679  -27.988 13.04   1   28.05  ? 129 LYS A C   1 
ATOM   1065 O O   . LYS A 1 133 ? -4.554  -27.411 13.68   1   31.14  ? 129 LYS A O   1 
ATOM   1066 C CB  . LYS A 1 133 ? -2.044  -26.656 11.552  1   22.65  ? 129 LYS A CB  1 
ATOM   1067 C CG  . LYS A 1 133 ? -2.167  -25.327 12.318  1   23.48  ? 129 LYS A CG  1 
ATOM   1068 C CD  . LYS A 1 133 ? -0.802  -24.749 12.652  1   27.76  ? 129 LYS A CD  1 
ATOM   1069 C CE  . LYS A 1 133 ? -0.79   -23.378 13.227  1   27.29  ? 129 LYS A CE  1 
ATOM   1070 N NZ  . LYS A 1 133 ? 0.524   -22.766 12.982  1   25.13  ? 129 LYS A NZ  1 
ATOM   1071 N N   . PRO A 1 134 ? -3.057  -29.065 13.551  1   25.79  ? 130 PRO A N   1 
ATOM   1072 C CA  . PRO A 1 134 ? -3.522  -29.665 14.804  1   26.33  ? 130 PRO A CA  1 
ATOM   1073 C C   . PRO A 1 134 ? -3.497  -28.77  16.05   1   30.47  ? 130 PRO A C   1 
ATOM   1074 O O   . PRO A 1 134 ? -4.372  -28.882 16.929  1   34.16  ? 130 PRO A O   1 
ATOM   1075 C CB  . PRO A 1 134 ? -2.663  -30.939 14.935  1   25.71  ? 130 PRO A CB  1 
ATOM   1076 C CG  . PRO A 1 134 ? -2.072  -31.163 13.564  1   24.82  ? 130 PRO A CG  1 
ATOM   1077 C CD  . PRO A 1 134 ? -1.979  -29.808 12.882  1   25.3   ? 130 PRO A CD  1 
ATOM   1078 N N   . GLN A 1 135 ? -2.499  -27.88  16.112  1   27.32  ? 131 GLN A N   1 
ATOM   1079 C CA  . GLN A 1 135 ? -2.399  -26.837 17.124  1   29.04  ? 131 GLN A CA  1 
ATOM   1080 C C   . GLN A 1 135 ? -3.679  -25.985 17.201  1   31.28  ? 131 GLN A C   1 
ATOM   1081 O O   . GLN A 1 135 ? -3.918  -25.36  18.234  1   34.66  ? 131 GLN A O   1 
ATOM   1082 C CB  . GLN A 1 135 ? -1.243  -25.879 16.8    1   30.96  ? 131 GLN A CB  1 
ATOM   1083 C CG  . GLN A 1 135 ? 0.174   -26.458 16.844  1   34.25  ? 131 GLN A CG  1 
ATOM   1084 C CD  . GLN A 1 135 ? 0.627   -27.313 15.664  1   42     ? 131 GLN A CD  1 
ATOM   1085 O OE1 . GLN A 1 135 ? -0.089  -27.61  14.687  1   34.51  ? 131 GLN A OE1 1 
ATOM   1086 N NE2 . GLN A 1 135 ? 1.879   -27.746 15.757  1   43.7   ? 131 GLN A NE2 1 
ATOM   1087 N N   . ASN A 1 136 ? -4.443  -25.866 16.093  1   28.12  ? 132 ASN A N   1 
ATOM   1088 C CA  . ASN A 1 136 ? -5.564  -24.935 16.004  1   27.85  ? 132 ASN A CA  1 
ATOM   1089 C C   . ASN A 1 136 ? -6.903  -25.676 16.022  1   26.56  ? 132 ASN A C   1 
ATOM   1090 O O   . ASN A 1 136 ? -7.928  -25.111 15.67   1   26.19  ? 132 ASN A O   1 
ATOM   1091 C CB  . ASN A 1 136 ? -5.522  -24.064 14.754  1   26.56  ? 132 ASN A CB  1 
ATOM   1092 C CG  . ASN A 1 136 ? -4.458  -22.996 14.793  1   27.79  ? 132 ASN A CG  1 
ATOM   1093 O OD1 . ASN A 1 136 ? -3.952  -22.64  15.866  1   29.71  ? 132 ASN A OD1 1 
ATOM   1094 N ND2 . ASN A 1 136 ? -4.081  -22.485 13.628  1   26.96  ? 132 ASN A ND2 1 
ATOM   1095 N N   . LEU A 1 137 ? -6.873  -26.943 16.441  1   25.54  ? 133 LEU A N   1 
ATOM   1096 C CA  . LEU A 1 137 ? -8.055  -27.762 16.607  1   23.49  ? 133 LEU A CA  1 
ATOM   1097 C C   . LEU A 1 137 ? -8.185  -28.158 18.077  1   23.18  ? 133 LEU A C   1 
ATOM   1098 O O   . LEU A 1 137 ? -7.378  -28.929 18.595  1   22.6   ? 133 LEU A O   1 
ATOM   1099 C CB  . LEU A 1 137 ? -7.882  -28.971 15.694  1   24.64  ? 133 LEU A CB  1 
ATOM   1100 C CG  . LEU A 1 137 ? -7.591  -28.669 14.218  1   26.4   ? 133 LEU A CG  1 
ATOM   1101 C CD1 . LEU A 1 137 ? -7.578  -29.967 13.403  1   26.02  ? 133 LEU A CD1 1 
ATOM   1102 C CD2 . LEU A 1 137 ? -8.652  -27.726 13.651  1   24.33  ? 133 LEU A CD2 1 
ATOM   1103 N N   . LEU A 1 138 ? -9.202  -27.612 18.751  1   21.28  ? 134 LEU A N   1 
ATOM   1104 C CA  . LEU A 1 138 ? -9.359  -27.831 20.175  1   23.07  ? 134 LEU A CA  1 
ATOM   1105 C C   . LEU A 1 138 ? -10.313 -28.994 20.439  1   24.23  ? 134 LEU A C   1 
ATOM   1106 O O   . LEU A 1 138 ? -11.296 -29.163 19.738  1   26.74  ? 134 LEU A O   1 
ATOM   1107 C CB  . LEU A 1 138 ? -9.839  -26.506 20.767  1   22.78  ? 134 LEU A CB  1 
ATOM   1108 C CG  . LEU A 1 138 ? -8.911  -25.313 20.497  1   22.92  ? 134 LEU A CG  1 
ATOM   1109 C CD1 . LEU A 1 138 ? -9.451  -24.083 21.16   1   18.85  ? 134 LEU A CD1 1 
ATOM   1110 C CD2 . LEU A 1 138 ? -7.454  -25.563 20.956  1   24.18  ? 134 LEU A CD2 1 
ATOM   1111 N N   . ILE A 1 139 ? -9.999  -29.799 21.454  1   25.73  ? 135 ILE A N   1 
ATOM   1112 C CA  . ILE A 1 139 ? -10.777 -30.964 21.836  1   25.11  ? 135 ILE A CA  1 
ATOM   1113 C C   . ILE A 1 139 ? -11.217 -30.774 23.281  1   25.01  ? 135 ILE A C   1 
ATOM   1114 O O   . ILE A 1 139 ? -10.488 -30.207 24.082  1   26.21  ? 135 ILE A O   1 
ATOM   1115 C CB  . ILE A 1 139 ? -9.96   -32.265 21.687  1   26.63  ? 135 ILE A CB  1 
ATOM   1116 C CG1 . ILE A 1 139 ? -8.709  -32.281 22.554  1   29.63  ? 135 ILE A CG1 1 
ATOM   1117 C CG2 . ILE A 1 139 ? -9.603  -32.558 20.236  1   25.7   ? 135 ILE A CG2 1 
ATOM   1118 C CD1 . ILE A 1 139 ? -7.987  -33.615 22.516  1   33.26  ? 135 ILE A CD1 1 
ATOM   1119 N N   . ASN A 1 140 ? -12.4   -31.284 23.626  1   27.76  ? 136 ASN A N   1 
ATOM   1120 C CA  . ASN A 1 140 ? -12.895 -31.181 24.995  1   27.49  ? 136 ASN A CA  1 
ATOM   1121 C C   . ASN A 1 140 ? -12.888 -32.559 25.664  1   27.7   ? 136 ASN A C   1 
ATOM   1122 O O   . ASN A 1 140 ? -12.412 -33.532 25.091  1   31.06  ? 136 ASN A O   1 
ATOM   1123 C CB  . ASN A 1 140 ? -14.227 -30.434 25.028  1   25.16  ? 136 ASN A CB  1 
ATOM   1124 C CG  . ASN A 1 140 ? -15.386 -31.222 24.457  1   25.82  ? 136 ASN A CG  1 
ATOM   1125 O OD1 . ASN A 1 140 ? -15.326 -32.446 24.251  1   24.87  ? 136 ASN A OD1 1 
ATOM   1126 N ND2 . ASN A 1 140 ? -16.479 -30.518 24.221  1   24.17  ? 136 ASN A ND2 1 
ATOM   1127 N N   . THR A 1 141 ? -13.427 -32.633 26.884  1   28.37  ? 137 THR A N   1 
ATOM   1128 C CA  . THR A 1 141 ? -13.517 -33.886 27.627  1   29.92  ? 137 THR A CA  1 
ATOM   1129 C C   . THR A 1 141 ? -14.625 -34.799 27.071  1   33.29  ? 137 THR A C   1 
ATOM   1130 O O   . THR A 1 141 ? -14.602 -36.015 27.275  1   31.7   ? 137 THR A O   1 
ATOM   1131 C CB  . THR A 1 141 ? -13.702 -33.571 29.116  1   27.11  ? 137 THR A CB  1 
ATOM   1132 O OG1 . THR A 1 141 ? -14.532 -32.417 29.186  1   25.67  ? 137 THR A OG1 1 
ATOM   1133 C CG2 . THR A 1 141 ? -12.421 -33.107 29.784  1   29.79  ? 137 THR A CG2 1 
ATOM   1134 N N   . GLU A 1 142 ? -15.599 -34.205 26.369  1   36.89  ? 138 GLU A N   1 
ATOM   1135 C CA  . GLU A 1 142 ? -16.812 -34.871 25.92   1   39.41  ? 138 GLU A CA  1 
ATOM   1136 C C   . GLU A 1 142 ? -16.627 -35.527 24.548  1   41.49  ? 138 GLU A C   1 
ATOM   1137 O O   . GLU A 1 142 ? -17.561 -36.16  24.047  1   40.32  ? 138 GLU A O   1 
ATOM   1138 C CB  . GLU A 1 142 ? -17.925 -33.826 25.78   1   43.05  ? 138 GLU A CB  1 
ATOM   1139 C CG  . GLU A 1 142 ? -18.41  -33.234 27.101  1   38.98  ? 138 GLU A CG  1 
ATOM   1140 C CD  . GLU A 1 142 ? -19.155 -34.264 27.924  1   44.03  ? 138 GLU A CD  1 
ATOM   1141 O OE1 . GLU A 1 142 ? -20.074 -34.928 27.39   1   43.81  ? 138 GLU A OE1 1 
ATOM   1142 O OE2 . GLU A 1 142 ? -18.823 -34.393 29.122  1   51.47  ? 138 GLU A OE2 1 
ATOM   1143 N N   . GLY A 1 143 ? -15.461 -35.313 23.911  1   38.93  ? 139 GLY A N   1 
ATOM   1144 C CA  . GLY A 1 143 ? -15.141 -35.939 22.635  1   31.64  ? 139 GLY A CA  1 
ATOM   1145 C C   . GLY A 1 143 ? -15.396 -35.037 21.427  1   30.04  ? 139 GLY A C   1 
ATOM   1146 O O   . GLY A 1 143 ? -15.454 -35.513 20.293  1   27.95  ? 139 GLY A O   1 
ATOM   1147 N N   . ALA A 1 144 ? -15.562 -33.733 21.654  1   29.14  ? 140 ALA A N   1 
ATOM   1148 C CA  . ALA A 1 144 ? -15.776 -32.821 20.537  1   28.7   ? 140 ALA A CA  1 
ATOM   1149 C C   . ALA A 1 144 ? -14.433 -32.24  20.092  1   28.89  ? 140 ALA A C   1 
ATOM   1150 O O   . ALA A 1 144 ? -13.51  -32.139 20.888  1   32.1   ? 140 ALA A O   1 
ATOM   1151 C CB  . ALA A 1 144 ? -16.73  -31.726 20.956  1   26.22  ? 140 ALA A CB  1 
ATOM   1152 N N   . ILE A 1 145 ? -14.336 -31.868 18.817  1   26.13  ? 141 ILE A N   1 
ATOM   1153 C CA  . ILE A 1 145 ? -13.187 -31.163 18.285  1   25.3   ? 141 ILE A CA  1 
ATOM   1154 C C   . ILE A 1 145 ? -13.716 -29.986 17.463  1   26.96  ? 141 ILE A C   1 
ATOM   1155 O O   . ILE A 1 145 ? -14.706 -30.123 16.743  1   24.3   ? 141 ILE A O   1 
ATOM   1156 C CB  . ILE A 1 145 ? -12.313 -32.107 17.439  1   27.28  ? 141 ILE A CB  1 
ATOM   1157 C CG1 . ILE A 1 145 ? -10.972 -31.442 17.051  1   25.2   ? 141 ILE A CG1 1 
ATOM   1158 C CG2 . ILE A 1 145 ? -13.09  -32.595 16.203  1   29.49  ? 141 ILE A CG2 1 
ATOM   1159 C CD1 . ILE A 1 145 ? -9.951  -32.393 16.471  1   24.6   ? 141 ILE A CD1 1 
ATOM   1160 N N   . LYS A 1 146 ? -13.05  -28.822 17.575  1   26.36  ? 142 LYS A N   1 
ATOM   1161 C CA  . LYS A 1 146 ? -13.594 -27.589 17.025  1   25.98  ? 142 LYS A CA  1 
ATOM   1162 C C   . LYS A 1 146 ? -12.49  -26.79  16.345  1   29.94  ? 142 LYS A C   1 
ATOM   1163 O O   . LYS A 1 146 ? -11.384 -26.706 16.881  1   33.18  ? 142 LYS A O   1 
ATOM   1164 C CB  . LYS A 1 146 ? -14.195 -26.751 18.156  1   22.02  ? 142 LYS A CB  1 
ATOM   1165 C CG  . LYS A 1 146 ? -15.1   -27.544 19.073  1   21.91  ? 142 LYS A CG  1 
ATOM   1166 C CD  . LYS A 1 146 ? -16.159 -26.746 19.835  1   21.85  ? 142 LYS A CD  1 
ATOM   1167 C CE  . LYS A 1 146 ? -17.017 -27.63  20.709  1   20.72  ? 142 LYS A CE  1 
ATOM   1168 N NZ  . LYS A 1 146 ? -18.32  -26.996 20.914  1   23.67  ? 142 LYS A NZ  1 
ATOM   1169 N N   . LEU A 1 147 ? -12.822 -26.17  15.202  1   28.62  ? 143 LEU A N   1 
ATOM   1170 C CA  . LEU A 1 147 ? -11.898 -25.271 14.523  1   29.17  ? 143 LEU A CA  1 
ATOM   1171 C C   . LEU A 1 147 ? -11.657 -24.063 15.424  1   30.06  ? 143 LEU A C   1 
ATOM   1172 O O   . LEU A 1 147 ? -12.614 -23.53  15.98   1   30.16  ? 143 LEU A O   1 
ATOM   1173 C CB  . LEU A 1 147 ? -12.385 -24.82  13.144  1   25.13  ? 143 LEU A CB  1 
ATOM   1174 C CG  . LEU A 1 147 ? -13.017 -25.883 12.239  1   27.09  ? 143 LEU A CG  1 
ATOM   1175 C CD1 . LEU A 1 147 ? -13.116 -25.353 10.821  1   27.16  ? 143 LEU A CD1 1 
ATOM   1176 C CD2 . LEU A 1 147 ? -12.341 -27.233 12.247  1   25.38  ? 143 LEU A CD2 1 
ATOM   1177 N N   . ALA A 1 148 ? -10.392 -23.627 15.52   1   27.18  ? 144 ALA A N   1 
ATOM   1178 C CA  . ALA A 1 148 ? -10.049 -22.451 16.308  1   28.02  ? 144 ALA A CA  1 
ATOM   1179 C C   . ALA A 1 148 ? -9.042  -21.586 15.561  1   27.43  ? 144 ALA A C   1 
ATOM   1180 O O   . ALA A 1 148 ? -8.54   -21.968 14.511  1   30.48  ? 144 ALA A O   1 
ATOM   1181 C CB  . ALA A 1 148 ? -9.524  -22.838 17.687  1   26.53  ? 144 ALA A CB  1 
ATOM   1182 N N   . ASP A 1 149 ? -8.786  -20.413 16.137  1   27.47  ? 145 ASP A N   1 
ATOM   1183 C CA  . ASP A 1 149 ? -7.843  -19.413 15.679  1   29.3   ? 145 ASP A CA  1 
ATOM   1184 C C   . ASP A 1 149 ? -8.173  -18.954 14.259  1   27.57  ? 145 ASP A C   1 
ATOM   1185 O O   . ASP A 1 149 ? -7.588  -19.454 13.295  1   25.38  ? 145 ASP A O   1 
ATOM   1186 C CB  . ASP A 1 149 ? -6.411  -19.88  15.873  1   34.89  ? 145 ASP A CB  1 
ATOM   1187 C CG  . ASP A 1 149 ? -5.365  -18.787 15.705  1   38.75  ? 145 ASP A CG  1 
ATOM   1188 O OD1 . ASP A 1 149 ? -5.713  -17.692 15.203  1   36.55  ? 145 ASP A OD1 1 
ATOM   1189 O OD2 . ASP A 1 149 ? -4.215  -19.03  16.121  1   48.14  ? 145 ASP A OD2 1 
ATOM   1190 N N   . PHE A 1 150 ? -9.045  -17.941 14.175  1   25.03  ? 146 PHE A N   1 
ATOM   1191 C CA  . PHE A 1 150 ? -9.525  -17.372 12.923  1   25.99  ? 146 PHE A CA  1 
ATOM   1192 C C   . PHE A 1 150 ? -8.785  -16.068 12.615  1   29.48  ? 146 PHE A C   1 
ATOM   1193 O O   . PHE A 1 150 ? -9.257  -15.235 11.833  1   28.5   ? 146 PHE A O   1 
ATOM   1194 C CB  . PHE A 1 150 ? -11.042 -17.162 13.017  1   23.78  ? 146 PHE A CB  1 
ATOM   1195 C CG  . PHE A 1 150 ? -11.841 -18.417 12.702  1   20.98  ? 146 PHE A CG  1 
ATOM   1196 C CD1 . PHE A 1 150 ? -11.952 -19.433 13.64   1   18.27  ? 146 PHE A CD1 1 
ATOM   1197 C CD2 . PHE A 1 150 ? -12.482 -18.569 11.473  1   19.62  ? 146 PHE A CD2 1 
ATOM   1198 C CE1 . PHE A 1 150 ? -12.674 -20.577 13.364  1   17.96  ? 146 PHE A CE1 1 
ATOM   1199 C CE2 . PHE A 1 150 ? -13.204 -19.723 11.202  1   18.97  ? 146 PHE A CE2 1 
ATOM   1200 C CZ  . PHE A 1 150 ? -13.296 -20.722 12.15   1   18.66  ? 146 PHE A CZ  1 
ATOM   1201 N N   . GLY A 1 151 ? -7.618  -15.901 13.245  1   29.78  ? 147 GLY A N   1 
ATOM   1202 C CA  . GLY A 1 151 ? -6.76   -14.755 12.989  1   31.86  ? 147 GLY A CA  1 
ATOM   1203 C C   . GLY A 1 151 ? -6.289  -14.677 11.538  1   30.48  ? 147 GLY A C   1 
ATOM   1204 O O   . GLY A 1 151 ? -6.085  -13.587 11.033  1   36.33  ? 147 GLY A O   1 
ATOM   1205 N N   . LEU A 1 152 ? -6.169  -15.813 10.855  1   31.54  ? 148 LEU A N   1 
ATOM   1206 C CA  . LEU A 1 152 ? -5.753  -15.799 9.459   1   35.56  ? 148 LEU A CA  1 
ATOM   1207 C C   . LEU A 1 152 ? -6.903  -16.002 8.474   1   31.46  ? 148 LEU A C   1 
ATOM   1208 O O   . LEU A 1 152 ? -6.639  -16.142 7.282   1   31.31  ? 148 LEU A O   1 
ATOM   1209 C CB  . LEU A 1 152 ? -4.667  -16.826 9.177   1   38.11  ? 148 LEU A CB  1 
ATOM   1210 C CG  . LEU A 1 152 ? -3.363  -16.541 9.902   1   47.27  ? 148 LEU A CG  1 
ATOM   1211 C CD1 . LEU A 1 152 ? -2.435  -17.731 9.639   1   56.54  ? 148 LEU A CD1 1 
ATOM   1212 C CD2 . LEU A 1 152 ? -2.88   -15.227 9.352   1   45.71  ? 148 LEU A CD2 1 
ATOM   1213 N N   . ALA A 1 153 ? -8.144  -15.994 8.964   1   28.41  ? 149 ALA A N   1 
ATOM   1214 C CA  . ALA A 1 153 ? -9.298  -16.337 8.152   1   29.66  ? 149 ALA A CA  1 
ATOM   1215 C C   . ALA A 1 153 ? -9.657  -15.172 7.226   1   29.15  ? 149 ALA A C   1 
ATOM   1216 O O   . ALA A 1 153 ? -9.083  -14.09  7.34    1   29.06  ? 149 ALA A O   1 
ATOM   1217 C CB  . ALA A 1 153 ? -10.425 -16.715 9.092   1   30.63  ? 149 ALA A CB  1 
ATOM   1218 N N   . ARG A 1 154 ? -10.565 -15.21  6.413   1   28.39  ? 150 ARG A N   1 
ATOM   1219 C CA  . ARG A 1 154 ? -10.963 -14.104 5.503   1   30.2   ? 150 ARG A CA  1 
ATOM   1220 C C   . ARG A 1 154 ? -12.33  -14.326 4.838   1   28.66  ? 150 ARG A C   1 
ATOM   1221 O O   . ARG A 1 154 ? -12.572 -15.462 4.395   1   30.7   ? 150 ARG A O   1 
ATOM   1222 C CB  . ARG A 1 154 ? -10.034 -14.104 4.288   1   31.67  ? 150 ARG A CB  1 
ATOM   1223 C CG  . ARG A 1 154 ? -10.242 -13.055 3.209   1   29.86  ? 150 ARG A CG  1 
ATOM   1224 C CD  . ARG A 1 154 ? -9.145  -12.028 3.335   1   33.72  ? 150 ARG A CD  1 
ATOM   1225 N NE  . ARG A 1 154 ? -8.622  -11.603 2.035   1   34.06  ? 150 ARG A NE  1 
ATOM   1226 C CZ  . ARG A 1 154 ? -8.684  -10.357 1.607   1   29.38  ? 150 ARG A CZ  1 
ATOM   1227 N NH1 . ARG A 1 154 ? -9.853  -9.758  1.508   1   27.12  ? 150 ARG A NH1 1 
ATOM   1228 N NH2 . ARG A 1 154 ? -7.579  -9.714  1.288   1   28.08  ? 150 ARG A NH2 1 
ATOM   1229 N N   . ALA A 1 155 ? -13.13  -13.437 4.674   1   26.5   ? 151 ALA A N   1 
ATOM   1230 C CA  . ALA A 1 155 ? -14.415 -13.446 3.981   1   22.67  ? 151 ALA A CA  1 
ATOM   1231 C C   . ALA A 1 155 ? -14.182 -13.395 2.483   1   22.43  ? 151 ALA A C   1 
ATOM   1232 O O   . ALA A 1 155 ? -13.614 -12.43  1.996   1   24.1   ? 151 ALA A O   1 
ATOM   1233 C CB  . ALA A 1 155 ? -15.24  -12.259 4.389   1   22.58  ? 151 ALA A CB  1 
ATOM   1234 N N   . PHE A 1 156 ? -14.618 -14.422 1.754   1   22.02  ? 152 PHE A N   1 
ATOM   1235 C CA  . PHE A 1 156 ? -14.386 -14.429 0.318   1   21.27  ? 152 PHE A CA  1 
ATOM   1236 C C   . PHE A 1 156 ? -15.657 -14.06  -0.44   1   23.72  ? 152 PHE A C   1 
ATOM   1237 O O   . PHE A 1 156 ? -16.784 -14.112 0.084   1   22.99  ? 152 PHE A O   1 
ATOM   1238 C CB  . PHE A 1 156 ? -13.794 -15.748 -0.164  1   21.61  ? 152 PHE A CB  1 
ATOM   1239 C CG  . PHE A 1 156 ? -14.612 -17.015 0.033   1   21.95  ? 152 PHE A CG  1 
ATOM   1240 C CD1 . PHE A 1 156 ? -14.534 -17.745 1.217   1   21.76  ? 152 PHE A CD1 1 
ATOM   1241 C CD2 . PHE A 1 156 ? -15.415 -17.499 -0.996  1   21.96  ? 152 PHE A CD2 1 
ATOM   1242 C CE1 . PHE A 1 156 ? -15.277 -18.912 1.375   1   22.39  ? 152 PHE A CE1 1 
ATOM   1243 C CE2 . PHE A 1 156 ? -16.128 -18.682 -0.86   1   21.11  ? 152 PHE A CE2 1 
ATOM   1244 C CZ  . PHE A 1 156 ? -16.075 -19.379 0.335   1   22.88  ? 152 PHE A CZ  1 
ATOM   1245 N N   . GLY A 1 157 ? -15.431 -13.587 -1.664  1   22.25  ? 153 GLY A N   1 
ATOM   1246 C CA  . GLY A 1 157 ? -16.487 -13.38  -2.631  1   17.99  ? 153 GLY A CA  1 
ATOM   1247 C C   . GLY A 1 157 ? -16.524 -14.543 -3.617  1   18.75  ? 153 GLY A C   1 
ATOM   1248 O O   . GLY A 1 157 ? -15.604 -15.366 -3.68   1   20.99  ? 153 GLY A O   1 
ATOM   1249 N N   . VAL A 1 158 ? -17.569 -14.553 -4.434  1   18.3   ? 154 VAL A N   1 
ATOM   1250 C CA  . VAL A 1 158 ? -17.789 -15.615 -5.394  1   21.06  ? 154 VAL A CA  1 
ATOM   1251 C C   . VAL A 1 158 ? -17.967 -14.964 -6.767  1   20.49  ? 154 VAL A C   1 
ATOM   1252 O O   . VAL A 1 158 ? -18.863 -14.122 -6.918  1   18.74  ? 154 VAL A O   1 
ATOM   1253 C CB  . VAL A 1 158 ? -19.048 -16.401 -4.979  1   25.09  ? 154 VAL A CB  1 
ATOM   1254 C CG1 . VAL A 1 158 ? -19.326 -17.511 -5.979  1   27.78  ? 154 VAL A CG1 1 
ATOM   1255 C CG2 . VAL A 1 158 ? -18.944 -16.971 -3.564  1   24.25  ? 154 VAL A CG2 1 
ATOM   1256 N N   . PRO A 1 159 ? -17.097 -15.245 -7.782  1   19.22  ? 155 PRO A N   1 
ATOM   1257 C CA  . PRO A 1 159 ? -15.849 -15.998 -7.603  1   19.85  ? 155 PRO A CA  1 
ATOM   1258 C C   . PRO A 1 159 ? -14.812 -15.282 -6.743  1   20.98  ? 155 PRO A C   1 
ATOM   1259 O O   . PRO A 1 159 ? -14.923 -14.08  -6.528  1   19.59  ? 155 PRO A O   1 
ATOM   1260 C CB  . PRO A 1 159 ? -15.307 -16.197 -9.02   1   18.67  ? 155 PRO A CB  1 
ATOM   1261 C CG  . PRO A 1 159 ? -15.905 -15.065 -9.787  1   19     ? 155 PRO A CG  1 
ATOM   1262 C CD  . PRO A 1 159 ? -17.268 -14.783 -9.165  1   18.59  ? 155 PRO A CD  1 
ATOM   1263 N N   . VAL A 1 160 ? -13.805 -16.028 -6.269  1   23.67  ? 156 VAL A N   1 
ATOM   1264 C CA  . VAL A 1 160 ? -12.774 -15.467 -5.401  1   24.93  ? 156 VAL A CA  1 
ATOM   1265 C C   . VAL A 1 160 ? -11.89  -14.505 -6.196  1   25.42  ? 156 VAL A C   1 
ATOM   1266 O O   . VAL A 1 160 ? -11.771 -14.609 -7.41   1   24.22  ? 156 VAL A O   1 
ATOM   1267 C CB  . VAL A 1 160 ? -11.914 -16.53  -4.706  1   23.25  ? 156 VAL A CB  1 
ATOM   1268 C CG1 . VAL A 1 160 ? -12.748 -17.415 -3.805  1   24.45  ? 156 VAL A CG1 1 
ATOM   1269 C CG2 . VAL A 1 160 ? -11.132 -17.362 -5.718  1   22.7   ? 156 VAL A CG2 1 
ATOM   1270 N N   . ARG A 1 161 ? -11.252 -13.631 -5.39   1   28.25  ? 157 ARG A N   1 
ATOM   1271 C CA  . ARG A 1 161 ? -10.289 -12.682 -5.954  1   33.52  ? 157 ARG A CA  1 
ATOM   1272 C C   . ARG A 1 161 ? -8.933  -13.09  -5.389  1   31.58  ? 157 ARG A C   1 
ATOM   1273 O O   . ARG A 1 161 ? -8.885  -14.036 -4.591  1   28.94  ? 157 ARG A O   1 
ATOM   1274 C CB  . ARG A 1 161 ? -10.729 -11.304 -5.462  1   35.55  ? 157 ARG A CB  1 
ATOM   1275 C CG  . ARG A 1 161 ? -10.048 -10.061 -6.007  1   47.55  ? 157 ARG A CG  1 
ATOM   1276 C CD  . ARG A 1 161 ? -10.417 -8.892  -5.119  1   52.38  ? 157 ARG A CD  1 
ATOM   1277 N NE  . ARG A 1 161 ? -9.919  -9.048  -3.749  1   56.02  ? 157 ARG A NE  1 
ATOM   1278 C CZ  . ARG A 1 161 ? -10.477 -8.491  -2.686  1   55.25  ? 157 ARG A CZ  1 
ATOM   1279 N NH1 . ARG A 1 161 ? -11.717 -8.043  -2.752  1   61.74  ? 157 ARG A NH1 1 
ATOM   1280 N NH2 . ARG A 1 161 ? -9.795  -8.383  -1.563  1   43.05  ? 157 ARG A NH2 1 
ATOM   1281 N N   . THR A 1 162 ? -7.87   -12.427 -5.838  1   31.55  ? 158 THR A N   1 
ATOM   1282 C CA  . THR A 1 162 ? -6.534  -12.67  -5.302  1   30.58  ? 158 THR A CA  1 
ATOM   1283 C C   . THR A 1 162 ? -6.489  -12.219 -3.846  1   27.34  ? 158 THR A C   1 
ATOM   1284 O O   . THR A 1 162 ? -6.784  -11.06  -3.567  1   25.87  ? 158 THR A O   1 
ATOM   1285 C CB  . THR A 1 162 ? -5.453  -11.955 -6.118  1   31.58  ? 158 THR A CB  1 
ATOM   1286 O OG1 . THR A 1 162 ? -5.536  -12.412 -7.465  1   35.47  ? 158 THR A OG1 1 
ATOM   1287 C CG2 . THR A 1 162 ? -4.054  -12.252 -5.598  1   26.29  ? 158 THR A CG2 1 
ATOM   1288 N N   . TYR A 1 163 ? -6.111  -13.136 -2.942  1   25.52  ? 159 TYR A N   1 
ATOM   1289 C CA  . TYR A 1 163 ? -5.874  -12.778 -1.545  1   26.6   ? 159 TYR A CA  1 
ATOM   1290 C C   . TYR A 1 163 ? -4.393  -12.963 -1.194  1   24.52  ? 159 TYR A C   1 
ATOM   1291 O O   . TYR A 1 163 ? -3.566  -13.182 -2.059  1   25.02  ? 159 TYR A O   1 
ATOM   1292 C CB  . TYR A 1 163 ? -6.813  -13.569 -0.629  1   27.46  ? 159 TYR A CB  1 
ATOM   1293 C CG  . TYR A 1 163 ? -8.279  -13.589 -1.04   1   28.73  ? 159 TYR A CG  1 
ATOM   1294 C CD1 . TYR A 1 163 ? -9      -12.419 -1.284  1   28.78  ? 159 TYR A CD1 1 
ATOM   1295 C CD2 . TYR A 1 163 ? -8.937  -14.798 -1.205  1   28.25  ? 159 TYR A CD2 1 
ATOM   1296 C CE1 . TYR A 1 163 ? -10.328 -12.464 -1.68   1   28.76  ? 159 TYR A CE1 1 
ATOM   1297 C CE2 . TYR A 1 163 ? -10.262 -14.853 -1.606  1   26.79  ? 159 TYR A CE2 1 
ATOM   1298 C CZ  . TYR A 1 163 ? -10.969 -13.687 -1.823  1   29.47  ? 159 TYR A CZ  1 
ATOM   1299 O OH  . TYR A 1 163 ? -12.284 -13.794 -2.212  1   33.05  ? 159 TYR A OH  1 
HETATM 1300 N N   . TPO A 1 164 ? -4.058  -12.87  0.085   1   24.6   ? 160 TPO A N   1 
HETATM 1301 C CA  . TPO A 1 164 ? -2.692  -12.945 0.555   1   24.68  ? 160 TPO A CA  1 
HETATM 1302 C CB  . TPO A 1 164 ? -2.688  -12.703 2.072   1   25.83  ? 160 TPO A CB  1 
HETATM 1303 C CG2 . TPO A 1 164 ? -1.3    -12.492 2.649   1   22.91  ? 160 TPO A CG2 1 
HETATM 1304 O OG1 . TPO A 1 164 ? -3.459  -11.479 2.33    1   23.92  ? 160 TPO A OG1 1 
HETATM 1305 P P   . TPO A 1 164 ? -4.845  -11.499 3.174   1   21.17  ? 160 TPO A P   1 
HETATM 1306 O O1P . TPO A 1 164 ? -5.776  -12.379 2.367   1   22.42  ? 160 TPO A O1P 1 
HETATM 1307 O O2P . TPO A 1 164 ? -5.239  -10.041 3.273   1   17.53  ? 160 TPO A O2P 1 
HETATM 1308 O O3P . TPO A 1 164 ? -4.558  -12.129 4.505   1   22.18  ? 160 TPO A O3P 1 
HETATM 1309 C C   . TPO A 1 164 ? -2.091  -14.307 0.202   1   27.54  ? 160 TPO A C   1 
HETATM 1310 O O   . TPO A 1 164 ? -2.74   -15.35  0.349   1   27.36  ? 160 TPO A O   1 
ATOM   1311 N N   . HIS A 1 165 ? -0.821  -14.275 -0.239  1   32.45  ? 161 HIS A N   1 
ATOM   1312 C CA  . HIS A 1 165 ? -0.097  -15.464 -0.667  1   39.23  ? 161 HIS A CA  1 
ATOM   1313 C C   . HIS A 1 165 ? 0.672   -16.073 0.506   1   42     ? 161 HIS A C   1 
ATOM   1314 O O   . HIS A 1 165 ? 0.8     -15.457 1.561   1   44.16  ? 161 HIS A O   1 
ATOM   1315 C CB  . HIS A 1 165 ? 0.796   -15.136 -1.867  1   42.73  ? 161 HIS A CB  1 
ATOM   1316 C CG  . HIS A 1 165 ? 1.644   -16.291 -2.31   1   70.19  ? 161 HIS A CG  1 
ATOM   1317 N ND1 . HIS A 1 165 ? 2.991   -16.099 -2.557  1   90.66  ? 161 HIS A ND1 1 
ATOM   1318 C CD2 . HIS A 1 165 ? 1.421   -17.612 -2.511  1   70.14  ? 161 HIS A CD2 1 
ATOM   1319 C CE1 . HIS A 1 165 ? 3.556   -17.248 -2.915  1   86.9   ? 161 HIS A CE1 1 
ATOM   1320 N NE2 . HIS A 1 165 ? 2.627   -18.185 -2.874  1   78.64  ? 161 HIS A NE2 1 
ATOM   1321 N N   . GLU A 1 166 ? 1.179   -17.301 0.325   1   50.92  ? 162 GLU A N   1 
ATOM   1322 C CA  . GLU A 1 166 ? 2.048   -17.953 1.304   1   59.03  ? 162 GLU A CA  1 
ATOM   1323 C C   . GLU A 1 166 ? 1.299   -18.132 2.631   1   58.34  ? 162 GLU A C   1 
ATOM   1324 O O   . GLU A 1 166 ? 1.912   -18.316 3.677   1   75.13  ? 162 GLU A O   1 
ATOM   1325 C CB  . GLU A 1 166 ? 3.367   -17.188 1.481   1   63.53  ? 162 GLU A CB  1 
ATOM   1326 C CG  . GLU A 1 166 ? 4.381   -17.428 0.365   1   69.94  ? 162 GLU A CG  1 
ATOM   1327 C CD  . GLU A 1 166 ? 5.5     -16.405 0.231   1   71.58  ? 162 GLU A CD  1 
ATOM   1328 O OE1 . GLU A 1 166 ? 5.716   -15.872 -0.884  1   73.46  ? 162 GLU A OE1 1 
ATOM   1329 O OE2 . GLU A 1 166 ? 6.165   -16.139 1.253   1   72.9   ? 162 GLU A OE2 1 
ATOM   1330 N N   . VAL A 1 167 ? -0.039  -18.078 2.58    1   46.31  ? 163 VAL A N   1 
ATOM   1331 C CA  . VAL A 1 167 ? -0.908  -18.327 3.724   1   35.45  ? 163 VAL A CA  1 
ATOM   1332 C C   . VAL A 1 167 ? -0.815  -19.808 4.072   1   33.14  ? 163 VAL A C   1 
ATOM   1333 O O   . VAL A 1 167 ? -0.314  -20.602 3.261   1   35.53  ? 163 VAL A O   1 
ATOM   1334 C CB  . VAL A 1 167 ? -2.358  -17.946 3.372   1   33.97  ? 163 VAL A CB  1 
ATOM   1335 C CG1 . VAL A 1 167 ? -2.576  -16.44  3.458   1   32.47  ? 163 VAL A CG1 1 
ATOM   1336 C CG2 . VAL A 1 167 ? -2.789  -18.485 2       1   30.69  ? 163 VAL A CG2 1 
ATOM   1337 N N   . VAL A 1 168 ? -1.278  -20.164 5.281   1   27.29  ? 164 VAL A N   1 
ATOM   1338 C CA  . VAL A 1 168 ? -1.297  -21.545 5.755   1   24.17  ? 164 VAL A CA  1 
ATOM   1339 C C   . VAL A 1 168 ? 0.112   -21.955 6.197   1   26.19  ? 164 VAL A C   1 
ATOM   1340 O O   . VAL A 1 168 ? 1.049   -21.84  5.413   1   27.17  ? 164 VAL A O   1 
ATOM   1341 C CB  . VAL A 1 168 ? -1.858  -22.523 4.697   1   20.47  ? 164 VAL A CB  1 
ATOM   1342 C CG1 . VAL A 1 168 ? -2.093  -23.914 5.266   1   18.29  ? 164 VAL A CG1 1 
ATOM   1343 C CG2 . VAL A 1 168 ? -3.158  -22.015 4.084   1   21.69  ? 164 VAL A CG2 1 
ATOM   1344 N N   . THR A 1 169 ? 0.248   -22.455 7.439   1   26.43  ? 165 THR A N   1 
ATOM   1345 C CA  . THR A 1 169 ? 1.499   -23.054 7.9     1   26.49  ? 165 THR A CA  1 
ATOM   1346 C C   . THR A 1 169 ? 1.959   -24.072 6.857   1   26.6   ? 165 THR A C   1 
ATOM   1347 O O   . THR A 1 169 ? 1.168   -24.925 6.405   1   22.39  ? 165 THR A O   1 
ATOM   1348 C CB  . THR A 1 169 ? 1.348   -23.75  9.258   1   26.05  ? 165 THR A CB  1 
ATOM   1349 O OG1 . THR A 1 169 ? 0.799   -22.729 10.08   1   25.12  ? 165 THR A OG1 1 
ATOM   1350 C CG2 . THR A 1 169 ? 2.67    -24.293 9.794   1   20.47  ? 165 THR A CG2 1 
ATOM   1351 N N   . LEU A 1 170 ? 3.259   -23.981 6.561   1   22.3   ? 166 LEU A N   1 
ATOM   1352 C CA  . LEU A 1 170 ? 3.893   -24.609 5.421   1   22.97  ? 166 LEU A CA  1 
ATOM   1353 C C   . LEU A 1 170 ? 3.499   -26.078 5.29    1   23.21  ? 166 LEU A C   1 
ATOM   1354 O O   . LEU A 1 170 ? 3.077   -26.5   4.207   1   24.94  ? 166 LEU A O   1 
ATOM   1355 C CB  . LEU A 1 170 ? 5.409   -24.439 5.532   1   22.63  ? 166 LEU A CB  1 
ATOM   1356 C CG  . LEU A 1 170 ? 6.222   -25.004 4.365   1   24.57  ? 166 LEU A CG  1 
ATOM   1357 C CD1 . LEU A 1 170 ? 5.841   -24.272 3.068   1   24.61  ? 166 LEU A CD1 1 
ATOM   1358 C CD2 . LEU A 1 170 ? 7.716   -24.896 4.679   1   22.24  ? 166 LEU A CD2 1 
ATOM   1359 N N   . TRP A 1 171 ? 3.653   -26.861 6.369   1   21.49  ? 167 TRP A N   1 
ATOM   1360 C CA  . TRP A 1 171 ? 3.425   -28.296 6.241   1   21.65  ? 167 TRP A CA  1 
ATOM   1361 C C   . TRP A 1 171 ? 2.007   -28.607 5.765   1   24.68  ? 167 TRP A C   1 
ATOM   1362 O O   . TRP A 1 171 ? 1.768   -29.716 5.289   1   27.64  ? 167 TRP A O   1 
ATOM   1363 C CB  . TRP A 1 171 ? 3.695   -29.043 7.549   1   19.79  ? 167 TRP A CB  1 
ATOM   1364 C CG  . TRP A 1 171 ? 5.116   -28.983 8.023   1   21.9   ? 167 TRP A CG  1 
ATOM   1365 C CD1 . TRP A 1 171 ? 6.207   -28.529 7.333   1   22.26  ? 167 TRP A CD1 1 
ATOM   1366 C CD2 . TRP A 1 171 ? 5.594   -29.432 9.302   1   20.73  ? 167 TRP A CD2 1 
ATOM   1367 N NE1 . TRP A 1 171 ? 7.322   -28.643 8.104   1   22.89  ? 167 TRP A NE1 1 
ATOM   1368 C CE2 . TRP A 1 171 ? 6.986   -29.197 9.316   1   23.9   ? 167 TRP A CE2 1 
ATOM   1369 C CE3 . TRP A 1 171 ? 4.986   -29.985 10.436  1   22.28  ? 167 TRP A CE3 1 
ATOM   1370 C CZ2 . TRP A 1 171 ? 7.784   -29.514 10.424  1   22.72  ? 167 TRP A CZ2 1 
ATOM   1371 C CZ3 . TRP A 1 171 ? 5.767   -30.313 11.525  1   21.89  ? 167 TRP A CZ3 1 
ATOM   1372 C CH2 . TRP A 1 171 ? 7.151   -30.074 11.517  1   22.38  ? 167 TRP A CH2 1 
ATOM   1373 N N   . TYR A 1 172 ? 1.068   -27.659 5.949   1   23.15  ? 168 TYR A N   1 
ATOM   1374 C CA  . TYR A 1 172 ? -0.353  -27.89  5.691   1   24.51  ? 168 TYR A CA  1 
ATOM   1375 C C   . TYR A 1 172 ? -0.807  -27.127 4.432   1   26.14  ? 168 TYR A C   1 
ATOM   1376 O O   . TYR A 1 172 ? -2.003  -27.071 4.122   1   24.69  ? 168 TYR A O   1 
ATOM   1377 C CB  . TYR A 1 172 ? -1.142  -27.576 6.978   1   20.96  ? 168 TYR A CB  1 
ATOM   1378 C CG  . TYR A 1 172 ? -0.649  -28.391 8.162   1   22.49  ? 168 TYR A CG  1 
ATOM   1379 C CD1 . TYR A 1 172 ? -1.08   -29.7   8.355   1   22.31  ? 168 TYR A CD1 1 
ATOM   1380 C CD2 . TYR A 1 172 ? 0.331   -27.89  9.035   1   24.99  ? 168 TYR A CD2 1 
ATOM   1381 C CE1 . TYR A 1 172 ? -0.566  -30.476 9.382   1   21.8   ? 168 TYR A CE1 1 
ATOM   1382 C CE2 . TYR A 1 172 ? 0.837   -28.647 10.082  1   20.92  ? 168 TYR A CE2 1 
ATOM   1383 C CZ  . TYR A 1 172 ? 0.381   -29.943 10.248  1   21.73  ? 168 TYR A CZ  1 
ATOM   1384 O OH  . TYR A 1 172 ? 0.857   -30.69  11.274  1   20.58  ? 168 TYR A OH  1 
ATOM   1385 N N   . ARG A 1 173 ? 0.167   -26.539 3.713   1   24.12  ? 169 ARG A N   1 
ATOM   1386 C CA  . ARG A 1 173 ? -0.108  -25.594 2.645   1   25.04  ? 169 ARG A CA  1 
ATOM   1387 C C   . ARG A 1 173 ? -0.305  -26.346 1.329   1   25.12  ? 169 ARG A C   1 
ATOM   1388 O O   . ARG A 1 173 ? 0.484   -27.236 1.033   1   25.62  ? 169 ARG A O   1 
ATOM   1389 C CB  . ARG A 1 173 ? 1.057   -24.594 2.547   1   23.25  ? 169 ARG A CB  1 
ATOM   1390 C CG  . ARG A 1 173 ? 0.837   -23.512 1.493   1   21.62  ? 169 ARG A CG  1 
ATOM   1391 C CD  . ARG A 1 173 ? 1.885   -22.432 1.509   1   19.61  ? 169 ARG A CD  1 
ATOM   1392 N NE  . ARG A 1 173 ? 2.209   -21.931 2.85    1   19.53  ? 169 ARG A NE  1 
ATOM   1393 C CZ  . ARG A 1 173 ? 3.331   -21.257 3.11    1   21.46  ? 169 ARG A CZ  1 
ATOM   1394 N NH1 . ARG A 1 173 ? 4.199   -20.964 2.144   1   19.92  ? 169 ARG A NH1 1 
ATOM   1395 N NH2 . ARG A 1 173 ? 3.578   -20.882 4.346   1   22.92  ? 169 ARG A NH2 1 
ATOM   1396 N N   . ALA A 1 174 ? -1.326  -25.956 0.543   1   21.52  ? 170 ALA A N   1 
ATOM   1397 C CA  . ALA A 1 174 ? -1.718  -26.645 -0.68   1   21.48  ? 170 ALA A CA  1 
ATOM   1398 C C   . ALA A 1 174 ? -0.774  -26.345 -1.856  1   22.82  ? 170 ALA A C   1 
ATOM   1399 O O   . ALA A 1 174 ? -0.206  -25.259 -1.977  1   22.86  ? 170 ALA A O   1 
ATOM   1400 C CB  . ALA A 1 174 ? -3.149  -26.261 -1.03   1   19.15  ? 170 ALA A CB  1 
ATOM   1401 N N   . PRO A 1 175 ? -0.658  -27.272 -2.83   1   24.01  ? 171 PRO A N   1 
ATOM   1402 C CA  . PRO A 1 175 ? 0.214   -27.071 -3.998  1   25.1   ? 171 PRO A CA  1 
ATOM   1403 C C   . PRO A 1 175 ? 0.031   -25.761 -4.765  1   25.07  ? 171 PRO A C   1 
ATOM   1404 O O   . PRO A 1 175 ? 1.018   -25.135 -5.195  1   21.14  ? 171 PRO A O   1 
ATOM   1405 C CB  . PRO A 1 175 ? -0.023  -28.302 -4.884  1   24.72  ? 171 PRO A CB  1 
ATOM   1406 C CG  . PRO A 1 175 ? -1.269  -28.909 -4.297  1   27.39  ? 171 PRO A CG  1 
ATOM   1407 C CD  . PRO A 1 175 ? -1.314  -28.586 -2.812  1   23.55  ? 171 PRO A CD  1 
ATOM   1408 N N   . GLU A 1 176 ? -1.244  -25.364 -4.921  1   24.14  ? 172 GLU A N   1 
ATOM   1409 C CA  . GLU A 1 176 ? -1.604  -24.183 -5.691  1   23.22  ? 172 GLU A CA  1 
ATOM   1410 C C   . GLU A 1 176 ? -1.046  -22.916 -5.017  1   25.29  ? 172 GLU A C   1 
ATOM   1411 O O   . GLU A 1 176 ? -0.662  -21.95  -5.695  1   26.36  ? 172 GLU A O   1 
ATOM   1412 C CB  . GLU A 1 176 ? -3.101  -24.186 -6.028  1   23.39  ? 172 GLU A CB  1 
ATOM   1413 C CG  . GLU A 1 176 ? -4.086  -24.178 -4.857  1   23.17  ? 172 GLU A CG  1 
ATOM   1414 C CD  . GLU A 1 176 ? -4.617  -25.494 -4.292  1   26.42  ? 172 GLU A CD  1 
ATOM   1415 O OE1 . GLU A 1 176 ? -5.721  -25.53  -3.682  1   26.57  ? 172 GLU A OE1 1 
ATOM   1416 O OE2 . GLU A 1 176 ? -3.912  -26.494 -4.417  1   25.73  ? 172 GLU A OE2 1 
ATOM   1417 N N   . ILE A 1 177 ? -0.981  -22.913 -3.667  1   22.49  ? 173 ILE A N   1 
ATOM   1418 C CA  . ILE A 1 177 ? -0.398  -21.771 -2.991  1   21.97  ? 173 ILE A CA  1 
ATOM   1419 C C   . ILE A 1 177 ? 1.117   -21.81  -3.197  1   22.11  ? 173 ILE A C   1 
ATOM   1420 O O   . ILE A 1 177 ? 1.742   -20.791 -3.461  1   22.74  ? 173 ILE A O   1 
ATOM   1421 C CB  . ILE A 1 177 ? -0.803  -21.72  -1.512  1   23.99  ? 173 ILE A CB  1 
ATOM   1422 C CG1 . ILE A 1 177 ? -2.326  -21.672 -1.368  1   25.83  ? 173 ILE A CG1 1 
ATOM   1423 C CG2 . ILE A 1 177 ? -0.153  -20.528 -0.804  1   22.6   ? 173 ILE A CG2 1 
ATOM   1424 C CD1 . ILE A 1 177 ? -2.818  -21.909 0.049   1   27.57  ? 173 ILE A CD1 1 
ATOM   1425 N N   . LEU A 1 178 ? 1.694   -23.006 -3.123  1   21.24  ? 174 LEU A N   1 
ATOM   1426 C CA  . LEU A 1 178 ? 3.127   -23.155 -3.248  1   23.19  ? 174 LEU A CA  1 
ATOM   1427 C C   . LEU A 1 178 ? 3.561   -22.74  -4.65   1   25.31  ? 174 LEU A C   1 
ATOM   1428 O O   . LEU A 1 178 ? 4.644   -22.168 -4.798  1   21.76  ? 174 LEU A O   1 
ATOM   1429 C CB  . LEU A 1 178 ? 3.528   -24.585 -2.891  1   23.18  ? 174 LEU A CB  1 
ATOM   1430 C CG  . LEU A 1 178 ? 3.365   -24.954 -1.414  1   21.85  ? 174 LEU A CG  1 
ATOM   1431 C CD1 . LEU A 1 178 ? 3.421   -26.455 -1.227  1   21.15  ? 174 LEU A CD1 1 
ATOM   1432 C CD2 . LEU A 1 178 ? 4.483   -24.266 -0.65   1   20.45  ? 174 LEU A CD2 1 
ATOM   1433 N N   . LEU A 1 179 ? 2.681   -22.954 -5.649  1   23.27  ? 175 LEU A N   1 
ATOM   1434 C CA  . LEU A 1 179 ? 3.012   -22.616 -7.026  1   23.79  ? 175 LEU A CA  1 
ATOM   1435 C C   . LEU A 1 179 ? 2.646   -21.174 -7.387  1   26.4   ? 175 LEU A C   1 
ATOM   1436 O O   . LEU A 1 179 ? 2.615   -20.816 -8.563  1   29.33  ? 175 LEU A O   1 
ATOM   1437 C CB  . LEU A 1 179 ? 2.325   -23.624 -7.941  1   22.41  ? 175 LEU A CB  1 
ATOM   1438 C CG  . LEU A 1 179 ? 2.914   -25.035 -7.91   1   22.31  ? 175 LEU A CG  1 
ATOM   1439 C CD1 . LEU A 1 179 ? 2.074   -26.024 -8.697  1   23.48  ? 175 LEU A CD1 1 
ATOM   1440 C CD2 . LEU A 1 179 ? 4.347   -25.01  -8.386  1   19.08  ? 175 LEU A CD2 1 
ATOM   1441 N N   . GLY A 1 180 ? 2.347   -20.344 -6.386  1   26.33  ? 176 GLY A N   1 
ATOM   1442 C CA  . GLY A 1 180 ? 2.079   -18.933 -6.614  1   26.69  ? 176 GLY A CA  1 
ATOM   1443 C C   . GLY A 1 180 ? 0.75    -18.649 -7.328  1   29.78  ? 176 GLY A C   1 
ATOM   1444 O O   . GLY A 1 180 ? 0.601   -17.561 -7.895  1   29.31  ? 176 GLY A O   1 
ATOM   1445 N N   . CYS A 1 181 ? -0.206  -19.601 -7.33   1   29.79  ? 177 CYS A N   1 
ATOM   1446 C CA  . CYS A 1 181 ? -1.375  -19.47  -8.21   1   34.11  ? 177 CYS A CA  1 
ATOM   1447 C C   . CYS A 1 181 ? -2.073  -18.129 -7.956  1   31.07  ? 177 CYS A C   1 
ATOM   1448 O O   . CYS A 1 181 ? -2.025  -17.622 -6.84   1   28.87  ? 177 CYS A O   1 
ATOM   1449 C CB  . CYS A 1 181 ? -2.292  -20.693 -8.151  1   44.28  ? 177 CYS A CB  1 
ATOM   1450 S SG  . CYS A 1 181 ? -1.835  -22.03  -9.312  1   54.44  ? 177 CYS A SG  1 
ATOM   1451 N N   . LYS A 1 182 ? -2.662  -17.525 -8.999  1   27.04  ? 178 LYS A N   1 
ATOM   1452 C CA  . LYS A 1 182 ? -3.32   -16.231 -8.862  1   27.66  ? 178 LYS A CA  1 
ATOM   1453 C C   . LYS A 1 182 ? -4.513  -16.297 -7.896  1   24.56  ? 178 LYS A C   1 
ATOM   1454 O O   . LYS A 1 182 ? -4.771  -15.362 -7.159  1   24.57  ? 178 LYS A O   1 
ATOM   1455 C CB  . LYS A 1 182 ? -3.742  -15.74  -10.253 1   33.61  ? 178 LYS A CB  1 
ATOM   1456 C CG  . LYS A 1 182 ? -4.55   -14.439 -10.308 1   41.37  ? 178 LYS A CG  1 
ATOM   1457 C CD  . LYS A 1 182 ? -5      -14.042 -11.716 1   49.68  ? 178 LYS A CD  1 
ATOM   1458 C CE  . LYS A 1 182 ? -5.253  -12.556 -11.867 1   55.87  ? 178 LYS A CE  1 
ATOM   1459 N NZ  . LYS A 1 182 ? -5.97   -12.209 -13.099 1   50.41  ? 178 LYS A NZ  1 
ATOM   1460 N N   . TYR A 1 183 ? -5.26   -17.4   -7.914  1   23.46  ? 179 TYR A N   1 
ATOM   1461 C CA  . TYR A 1 183 ? -6.489  -17.52  -7.146  1   23.38  ? 179 TYR A CA  1 
ATOM   1462 C C   . TYR A 1 183 ? -6.454  -18.829 -6.374  1   21.35  ? 179 TYR A C   1 
ATOM   1463 O O   . TYR A 1 183 ? -5.965  -19.835 -6.876  1   19.09  ? 179 TYR A O   1 
ATOM   1464 C CB  . TYR A 1 183 ? -7.69   -17.65  -8.096  1   24.12  ? 179 TYR A CB  1 
ATOM   1465 C CG  . TYR A 1 183 ? -7.988  -16.433 -8.961  1   23.89  ? 179 TYR A CG  1 
ATOM   1466 C CD1 . TYR A 1 183 ? -8.162  -15.182 -8.378  1   22.94  ? 179 TYR A CD1 1 
ATOM   1467 C CD2 . TYR A 1 183 ? -8.065  -16.53  -10.356 1   25.5   ? 179 TYR A CD2 1 
ATOM   1468 C CE1 . TYR A 1 183 ? -8.434  -14.063 -9.151  1   24.49  ? 179 TYR A CE1 1 
ATOM   1469 C CE2 . TYR A 1 183 ? -8.356  -15.421 -11.145 1   25.09  ? 179 TYR A CE2 1 
ATOM   1470 C CZ  . TYR A 1 183 ? -8.53   -14.187 -10.53  1   26.71  ? 179 TYR A CZ  1 
ATOM   1471 O OH  . TYR A 1 183 ? -8.812  -13.052 -11.222 1   27.57  ? 179 TYR A OH  1 
ATOM   1472 N N   . TYR A 1 184 ? -7.006  -18.799 -5.161  1   20.64  ? 180 TYR A N   1 
ATOM   1473 C CA  . TYR A 1 184 ? -7.219  -20.016 -4.406  1   23.7   ? 180 TYR A CA  1 
ATOM   1474 C C   . TYR A 1 184 ? -8.578  -19.922 -3.695  1   25.22  ? 180 TYR A C   1 
ATOM   1475 O O   . TYR A 1 184 ? -9.135  -18.836 -3.523  1   23.31  ? 180 TYR A O   1 
ATOM   1476 C CB  . TYR A 1 184 ? -6.021  -20.322 -3.493  1   21.23  ? 180 TYR A CB  1 
ATOM   1477 C CG  . TYR A 1 184 ? -5.834  -19.326 -2.36   1   24.9   ? 180 TYR A CG  1 
ATOM   1478 C CD1 . TYR A 1 184 ? -6.686  -19.298 -1.238  1   22.56  ? 180 TYR A CD1 1 
ATOM   1479 C CD2 . TYR A 1 184 ? -4.775  -18.421 -2.406  1   22.05  ? 180 TYR A CD2 1 
ATOM   1480 C CE1 . TYR A 1 184 ? -6.476  -18.383 -0.216  1   22.17  ? 180 TYR A CE1 1 
ATOM   1481 C CE2 . TYR A 1 184 ? -4.571  -17.498 -1.393  1   21.95  ? 180 TYR A CE2 1 
ATOM   1482 C CZ  . TYR A 1 184 ? -5.423  -17.473 -0.304  1   23.33  ? 180 TYR A CZ  1 
ATOM   1483 O OH  . TYR A 1 184 ? -5.141  -16.526 0.644   1   26.01  ? 180 TYR A OH  1 
ATOM   1484 N N   . SER A 1 185 ? -9.067  -21.079 -3.233  1   23.96  ? 181 SER A N   1 
ATOM   1485 C CA  . SER A 1 185 ? -10.451 -21.19  -2.817  1   26.75  ? 181 SER A CA  1 
ATOM   1486 C C   . SER A 1 185 ? -10.543 -22.14  -1.632  1   27.23  ? 181 SER A C   1 
ATOM   1487 O O   . SER A 1 185 ? -9.555  -22.387 -0.928  1   31.05  ? 181 SER A O   1 
ATOM   1488 C CB  . SER A 1 185 ? -11.363 -21.645 -3.974  1   24.56  ? 181 SER A CB  1 
ATOM   1489 O OG  . SER A 1 185 ? -12.704 -21.232 -3.716  1   24.17  ? 181 SER A OG  1 
ATOM   1490 N N   . THR A 1 186 ? -11.743 -22.698 -1.475  1   24.44  ? 182 THR A N   1 
ATOM   1491 C CA  . THR A 1 186 ? -12.083 -23.556 -0.35   1   25.33  ? 182 THR A CA  1 
ATOM   1492 C C   . THR A 1 186 ? -11.218 -24.811 -0.355  1   24.35  ? 182 THR A C   1 
ATOM   1493 O O   . THR A 1 186 ? -11.037 -25.437 0.679   1   27.8   ? 182 THR A O   1 
ATOM   1494 C CB  . THR A 1 186 ? -13.577 -23.892 -0.412  1   24.49  ? 182 THR A CB  1 
ATOM   1495 O OG1 . THR A 1 186 ? -13.856 -24.391 -1.72   1   22.88  ? 182 THR A OG1 1 
ATOM   1496 C CG2 . THR A 1 186 ? -14.459 -22.689 -0.11   1   21.72  ? 182 THR A CG2 1 
ATOM   1497 N N   . ALA A 1 187 ? -10.713 -25.185 -1.533  1   24.22  ? 183 ALA A N   1 
ATOM   1498 C CA  . ALA A 1 187 ? -9.866  -26.353 -1.693  1   24.69  ? 183 ALA A CA  1 
ATOM   1499 C C   . ALA A 1 187 ? -8.597  -26.284 -0.825  1   24.5   ? 183 ALA A C   1 
ATOM   1500 O O   . ALA A 1 187 ? -8.126  -27.323 -0.391  1   26.67  ? 183 ALA A O   1 
ATOM   1501 C CB  . ALA A 1 187 ? -9.584  -26.555 -3.151  1   21.6   ? 183 ALA A CB  1 
ATOM   1502 N N   . VAL A 1 188 ? -8.071  -25.087 -0.504  1   24.99  ? 184 VAL A N   1 
ATOM   1503 C CA  . VAL A 1 188 ? -6.916  -24.987 0.399   1   25.81  ? 184 VAL A CA  1 
ATOM   1504 C C   . VAL A 1 188 ? -7.237  -25.462 1.829   1   27.27  ? 184 VAL A C   1 
ATOM   1505 O O   . VAL A 1 188 ? -6.374  -26.028 2.487   1   28.71  ? 184 VAL A O   1 
ATOM   1506 C CB  . VAL A 1 188 ? -6.231  -23.614 0.443   1   24.5   ? 184 VAL A CB  1 
ATOM   1507 C CG1 . VAL A 1 188 ? -6.107  -23.003 -0.941  1   22.56  ? 184 VAL A CG1 1 
ATOM   1508 C CG2 . VAL A 1 188 ? -6.931  -22.67  1.406   1   25.4   ? 184 VAL A CG2 1 
ATOM   1509 N N   . ASP A 1 189 ? -8.494  -25.337 2.296   1   26.91  ? 185 ASP A N   1 
ATOM   1510 C CA  . ASP A 1 189 ? -8.829  -25.825 3.622   1   24.94  ? 185 ASP A CA  1 
ATOM   1511 C C   . ASP A 1 189 ? -8.859  -27.347 3.6     1   24.88  ? 185 ASP A C   1 
ATOM   1512 O O   . ASP A 1 189 ? -8.343  -27.981 4.524   1   27.06  ? 185 ASP A O   1 
ATOM   1513 C CB  . ASP A 1 189 ? -10.097 -25.204 4.197   1   27.75  ? 185 ASP A CB  1 
ATOM   1514 C CG  . ASP A 1 189 ? -9.977  -23.752 4.634   1   30.99  ? 185 ASP A CG  1 
ATOM   1515 O OD1 . ASP A 1 189 ? -8.83   -23.329 4.919   1   30.57  ? 185 ASP A OD1 1 
ATOM   1516 O OD2 . ASP A 1 189 ? -11.032 -23.041 4.661   1   32.57  ? 185 ASP A OD2 1 
ATOM   1517 N N   . ILE A 1 190 ? -9.404  -27.922 2.519   1   22.94  ? 186 ILE A N   1 
ATOM   1518 C CA  . ILE A 1 190 ? -9.51   -29.369 2.409   1   23.55  ? 186 ILE A CA  1 
ATOM   1519 C C   . ILE A 1 190 ? -8.115  -30.008 2.422   1   24.89  ? 186 ILE A C   1 
ATOM   1520 O O   . ILE A 1 190 ? -7.891  -31.042 3.093   1   24.97  ? 186 ILE A O   1 
ATOM   1521 C CB  . ILE A 1 190 ? -10.383 -29.786 1.206   1   22.86  ? 186 ILE A CB  1 
ATOM   1522 C CG1 . ILE A 1 190 ? -11.875 -29.448 1.479   1   24.45  ? 186 ILE A CG1 1 
ATOM   1523 C CG2 . ILE A 1 190 ? -10.198 -31.272 0.863   1   19.78  ? 186 ILE A CG2 1 
ATOM   1524 C CD1 . ILE A 1 190 ? -12.497 -30.274 2.593   1   24.75  ? 186 ILE A CD1 1 
ATOM   1525 N N   . TRP A 1 191 ? -7.177  -29.385 1.689   1   23.04  ? 187 TRP A N   1 
ATOM   1526 C CA  . TRP A 1 191 ? -5.827  -29.937 1.632   1   24.4   ? 187 TRP A CA  1 
ATOM   1527 C C   . TRP A 1 191 ? -5.278  -30.084 3.045   1   24.49  ? 187 TRP A C   1 
ATOM   1528 O O   . TRP A 1 191 ? -4.742  -31.131 3.419   1   31.58  ? 187 TRP A O   1 
ATOM   1529 C CB  . TRP A 1 191 ? -4.913  -29.077 0.746   1   23.38  ? 187 TRP A CB  1 
ATOM   1530 C CG  . TRP A 1 191 ? -3.511  -29.614 0.674   1   23.94  ? 187 TRP A CG  1 
ATOM   1531 C CD1 . TRP A 1 191 ? -2.524  -29.418 1.594   1   22.77  ? 187 TRP A CD1 1 
ATOM   1532 C CD2 . TRP A 1 191 ? -2.954  -30.47  -0.346  1   23.25  ? 187 TRP A CD2 1 
ATOM   1533 N NE1 . TRP A 1 191 ? -1.401  -30.1   1.222   1   23.8   ? 187 TRP A NE1 1 
ATOM   1534 C CE2 . TRP A 1 191 ? -1.623  -30.739 0.032   1   23.38  ? 187 TRP A CE2 1 
ATOM   1535 C CE3 . TRP A 1 191 ? -3.438  -31.013 -1.54   1   22.47  ? 187 TRP A CE3 1 
ATOM   1536 C CZ2 . TRP A 1 191 ? -0.77   -31.529 -0.739  1   22.08  ? 187 TRP A CZ2 1 
ATOM   1537 C CZ3 . TRP A 1 191 ? -2.589  -31.776 -2.312  1   23.34  ? 187 TRP A CZ3 1 
ATOM   1538 C CH2 . TRP A 1 191 ? -1.269  -32.036 -1.914  1   22.22  ? 187 TRP A CH2 1 
ATOM   1539 N N   . SER A 1 192 ? -5.381  -29.003 3.822   1   27     ? 188 SER A N   1 
ATOM   1540 C CA  . SER A 1 192 ? -4.93   -28.975 5.214   1   26.46  ? 188 SER A CA  1 
ATOM   1541 C C   . SER A 1 192 ? -5.544  -30.127 6.012   1   24.04  ? 188 SER A C   1 
ATOM   1542 O O   . SER A 1 192 ? -4.839  -30.92  6.628   1   23.39  ? 188 SER A O   1 
ATOM   1543 C CB  . SER A 1 192 ? -5.229  -27.64  5.849   1   27.4   ? 188 SER A CB  1 
ATOM   1544 O OG  . SER A 1 192 ? -4.459  -26.606 5.248   1   25.94  ? 188 SER A OG  1 
ATOM   1545 N N   . LEU A 1 193 ? -6.875  -30.222 5.97    1   26.35  ? 189 LEU A N   1 
ATOM   1546 C CA  . LEU A 1 193 ? -7.624  -31.283 6.626   1   24.41  ? 189 LEU A CA  1 
ATOM   1547 C C   . LEU A 1 193 ? -7.122  -32.651 6.181   1   23.32  ? 189 LEU A C   1 
ATOM   1548 O O   . LEU A 1 193 ? -7.122  -33.586 6.971   1   24.32  ? 189 LEU A O   1 
ATOM   1549 C CB  . LEU A 1 193 ? -9.122  -31.142 6.356   1   22.44  ? 189 LEU A CB  1 
ATOM   1550 C CG  . LEU A 1 193 ? -9.916  -30.257 7.314   1   25.75  ? 189 LEU A CG  1 
ATOM   1551 C CD1 . LEU A 1 193 ? -11.389 -30.68  7.239   1   22.35  ? 189 LEU A CD1 1 
ATOM   1552 C CD2 . LEU A 1 193 ? -9.392  -30.407 8.752   1   25.88  ? 189 LEU A CD2 1 
ATOM   1553 N N   . GLY A 1 194 ? -6.809  -32.8   4.887   1   23.96  ? 190 GLY A N   1 
ATOM   1554 C CA  . GLY A 1 194 ? -6.235  -34.047 4.398   1   22.39  ? 190 GLY A CA  1 
ATOM   1555 C C   . GLY A 1 194 ? -4.894  -34.354 5.078   1   21.08  ? 190 GLY A C   1 
ATOM   1556 O O   . GLY A 1 194 ? -4.679  -35.448 5.6     1   21.98  ? 190 GLY A O   1 
ATOM   1557 N N   . CYS A 1 195 ? -3.99   -33.373 5.083   1   21.44  ? 191 CYS A N   1 
ATOM   1558 C CA  . CYS A 1 195 ? -2.729  -33.512 5.803   1   21.6   ? 191 CYS A CA  1 
ATOM   1559 C C   . CYS A 1 195 ? -3.006  -33.923 7.252   1   22.41  ? 191 CYS A C   1 
ATOM   1560 O O   . CYS A 1 195 ? -2.307  -34.779 7.784   1   21.23  ? 191 CYS A O   1 
ATOM   1561 C CB  . CYS A 1 195 ? -1.92   -32.224 5.717   1   21.79  ? 191 CYS A CB  1 
ATOM   1562 S SG  . CYS A 1 195 ? -1.352  -31.814 4.039   1   23.95  ? 191 CYS A SG  1 
ATOM   1563 N N   . ILE A 1 196 ? -4.05   -33.341 7.882   1   23.37  ? 192 ILE A N   1 
ATOM   1564 C CA  . ILE A 1 196 ? -4.394  -33.564 9.28    1   20.99  ? 192 ILE A CA  1 
ATOM   1565 C C   . ILE A 1 196 ? -4.881  -34.997 9.473   1   23.35  ? 192 ILE A C   1 
ATOM   1566 O O   . ILE A 1 196 ? -4.427  -35.672 10.408  1   24.21  ? 192 ILE A O   1 
ATOM   1567 C CB  . ILE A 1 196 ? -5.384  -32.487 9.752   1   23.11  ? 192 ILE A CB  1 
ATOM   1568 C CG1 . ILE A 1 196 ? -4.658  -31.139 9.8     1   24.14  ? 192 ILE A CG1 1 
ATOM   1569 C CG2 . ILE A 1 196 ? -6.067  -32.829 11.086  1   20.95  ? 192 ILE A CG2 1 
ATOM   1570 C CD1 . ILE A 1 196 ? -5.536  -29.965 10.176  1   23.2   ? 192 ILE A CD1 1 
ATOM   1571 N N   . PHE A 1 197 ? -5.762  -35.477 8.571   1   21.83  ? 193 PHE A N   1 
ATOM   1572 C CA  . PHE A 1 197 ? -6.209  -36.872 8.56    1   22.15  ? 193 PHE A CA  1 
ATOM   1573 C C   . PHE A 1 197 ? -5.007  -37.827 8.614   1   21.84  ? 193 PHE A C   1 
ATOM   1574 O O   . PHE A 1 197 ? -4.892  -38.639 9.527   1   25.15  ? 193 PHE A O   1 
ATOM   1575 C CB  . PHE A 1 197 ? -7.131  -37.082 7.353   1   21.11  ? 193 PHE A CB  1 
ATOM   1576 C CG  . PHE A 1 197 ? -7.724  -38.465 7.145   1   21.65  ? 193 PHE A CG  1 
ATOM   1577 C CD1 . PHE A 1 197 ? -7.67   -39.447 8.142   1   20.99  ? 193 PHE A CD1 1 
ATOM   1578 C CD2 . PHE A 1 197 ? -8.372  -38.777 5.946   1   21.06  ? 193 PHE A CD2 1 
ATOM   1579 C CE1 . PHE A 1 197 ? -8.25   -40.702 7.93    1   21.23  ? 193 PHE A CE1 1 
ATOM   1580 C CE2 . PHE A 1 197 ? -8.948  -40.036 5.737   1   20.93  ? 193 PHE A CE2 1 
ATOM   1581 C CZ  . PHE A 1 197 ? -8.905  -40.996 6.735   1   21.26  ? 193 PHE A CZ  1 
ATOM   1582 N N   . ALA A 1 198 ? -4.109  -37.728 7.632   1   21.23  ? 194 ALA A N   1 
ATOM   1583 C CA  . ALA A 1 198 ? -2.914  -38.558 7.618   1   23.34  ? 194 ALA A CA  1 
ATOM   1584 C C   . ALA A 1 198 ? -2.228  -38.483 8.978   1   24.13  ? 194 ALA A C   1 
ATOM   1585 O O   . ALA A 1 198 ? -1.848  -39.512 9.54    1   27.74  ? 194 ALA A O   1 
ATOM   1586 C CB  . ALA A 1 198 ? -1.988  -38.156 6.475   1   23.16  ? 194 ALA A CB  1 
ATOM   1587 N N   . GLU A 1 199 ? -2.117  -37.259 9.516   1   24.76  ? 195 GLU A N   1 
ATOM   1588 C CA  . GLU A 1 199 ? -1.327  -37.001 10.711  1   25.79  ? 195 GLU A CA  1 
ATOM   1589 C C   . GLU A 1 199 ? -1.934  -37.698 11.924  1   27.36  ? 195 GLU A C   1 
ATOM   1590 O O   . GLU A 1 199 ? -1.22   -38.253 12.742  1   32.08  ? 195 GLU A O   1 
ATOM   1591 C CB  . GLU A 1 199 ? -1.135  -35.501 10.925  1   24.51  ? 195 GLU A CB  1 
ATOM   1592 C CG  . GLU A 1 199 ? -0.122  -35.189 12.025  1   24.39  ? 195 GLU A CG  1 
ATOM   1593 C CD  . GLU A 1 199 ? 0.386   -33.762 12.071  1   24.51  ? 195 GLU A CD  1 
ATOM   1594 O OE1 . GLU A 1 199 ? 0.273   -33.094 11.011  1   24.06  ? 195 GLU A OE1 1 
ATOM   1595 O OE2 . GLU A 1 199 ? 0.904   -33.342 13.151  1   23.89  ? 195 GLU A OE2 1 
ATOM   1596 N N   . MET A 1 200 ? -3.257  -37.687 12.023  1   28.55  ? 196 MET A N   1 
ATOM   1597 C CA  . MET A 1 200 ? -3.95   -38.372 13.108  1   27.59  ? 196 MET A CA  1 
ATOM   1598 C C   . MET A 1 200 ? -3.696  -39.879 13.065  1   26.23  ? 196 MET A C   1 
ATOM   1599 O O   . MET A 1 200 ? -3.763  -40.515 14.115  1   25.22  ? 196 MET A O   1 
ATOM   1600 C CB  . MET A 1 200 ? -5.469  -38.127 13.038  1   25.89  ? 196 MET A CB  1 
ATOM   1601 C CG  . MET A 1 200 ? -5.894  -36.751 13.519  1   24.45  ? 196 MET A CG  1 
ATOM   1602 S SD  . MET A 1 200 ? -7.676  -36.623 13.78   1   24.31  ? 196 MET A SD  1 
ATOM   1603 C CE  . MET A 1 200 ? -8.172  -36.438 12.065  1   23.76  ? 196 MET A CE  1 
ATOM   1604 N N   . VAL A 1 201 ? -3.47   -40.436 11.858  1   24.45  ? 197 VAL A N   1 
ATOM   1605 C CA  . VAL A 1 201 ? -3.284  -41.87  11.692  1   24.03  ? 197 VAL A CA  1 
ATOM   1606 C C   . VAL A 1 201 ? -1.858  -42.249 12.084  1   24.45  ? 197 VAL A C   1 
ATOM   1607 O O   . VAL A 1 201 ? -1.655  -43.261 12.747  1   25.89  ? 197 VAL A O   1 
ATOM   1608 C CB  . VAL A 1 201 ? -3.615  -42.458 10.305  1   23.22  ? 197 VAL A CB  1 
ATOM   1609 C CG1 . VAL A 1 201 ? -3.253  -43.931 10.277  1   20.67  ? 197 VAL A CG1 1 
ATOM   1610 C CG2 . VAL A 1 201 ? -5.072  -42.294 9.889   1   19.7   ? 197 VAL A CG2 1 
ATOM   1611 N N   . THR A 1 202 ? -0.882  -41.424 11.685  1   26.74  ? 198 THR A N   1 
ATOM   1612 C CA  . THR A 1 202 ? 0.539   -41.756 11.846  1   27.93  ? 198 THR A CA  1 
ATOM   1613 C C   . THR A 1 202 ? 1.118   -41.043 13.063  1   27.4   ? 198 THR A C   1 
ATOM   1614 O O   . THR A 1 202 ? 2.091   -41.511 13.611  1   27.35  ? 198 THR A O   1 
ATOM   1615 C CB  . THR A 1 202 ? 1.364   -41.385 10.611  1   27.76  ? 198 THR A CB  1 
ATOM   1616 O OG1 . THR A 1 202 ? 1.35    -39.954 10.598  1   31.98  ? 198 THR A OG1 1 
ATOM   1617 C CG2 . THR A 1 202 ? 0.784   -41.895 9.303   1   25.51  ? 198 THR A CG2 1 
ATOM   1618 N N   . ARG A 1 203 ? 0.535   -39.901 13.445  1   30.77  ? 199 ARG A N   1 
ATOM   1619 C CA  . ARG A 1 203 ? 1.067   -39.019 14.475  1   35.49  ? 199 ARG A CA  1 
ATOM   1620 C C   . ARG A 1 203 ? 2.359   -38.335 14.017  1   35.07  ? 199 ARG A C   1 
ATOM   1621 O O   . ARG A 1 203 ? 3.127   -37.865 14.851  1   36.45  ? 199 ARG A O   1 
ATOM   1622 C CB  . ARG A 1 203 ? 1.285   -39.725 15.817  1   37.34  ? 199 ARG A CB  1 
ATOM   1623 C CG  . ARG A 1 203 ? 0.045   -39.833 16.685  1   42.39  ? 199 ARG A CG  1 
ATOM   1624 C CD  . ARG A 1 203 ? 0.071   -41.144 17.445  1   42.24  ? 199 ARG A CD  1 
ATOM   1625 N NE  . ARG A 1 203 ? -0.138  -42.229 16.482  1   48.74  ? 199 ARG A NE  1 
ATOM   1626 C CZ  . ARG A 1 203 ? 0.533   -43.371 16.423  1   49.63  ? 199 ARG A CZ  1 
ATOM   1627 N NH1 . ARG A 1 203 ? 1.412   -43.703 17.358  1   51.71  ? 199 ARG A NH1 1 
ATOM   1628 N NH2 . ARG A 1 203 ? 0.291   -44.191 15.42   1   49.38  ? 199 ARG A NH2 1 
ATOM   1629 N N   . ARG A 1 204 ? 2.568   -38.219 12.704  1   33.24  ? 200 ARG A N   1 
ATOM   1630 C CA  . ARG A 1 204 ? 3.624   -37.366 12.164  1   34.3   ? 200 ARG A CA  1 
ATOM   1631 C C   . ARG A 1 204 ? 3.102   -36.579 10.963  1   31.78  ? 200 ARG A C   1 
ATOM   1632 O O   . ARG A 1 204 ? 2.216   -37.05  10.254  1   33.86  ? 200 ARG A O   1 
ATOM   1633 C CB  . ARG A 1 204 ? 4.854   -38.187 11.771  1   34.18  ? 200 ARG A CB  1 
ATOM   1634 C CG  . ARG A 1 204 ? 4.548   -39.304 10.788  1   35.69  ? 200 ARG A CG  1 
ATOM   1635 C CD  . ARG A 1 204 ? 5.764   -40.127 10.394  1   41.16  ? 200 ARG A CD  1 
ATOM   1636 N NE  . ARG A 1 204 ? 5.68    -40.57  8.992   1   44.13  ? 200 ARG A NE  1 
ATOM   1637 C CZ  . ARG A 1 204 ? 6.588   -41.332 8.375   1   46.38  ? 200 ARG A CZ  1 
ATOM   1638 N NH1 . ARG A 1 204 ? 7.698   -41.667 9.008   1   51.92  ? 200 ARG A NH1 1 
ATOM   1639 N NH2 . ARG A 1 204 ? 6.398   -41.767 7.141   1   41.1   ? 200 ARG A NH2 1 
ATOM   1640 N N   . ALA A 1 205 ? 3.66    -35.383 10.737  1   29.45  ? 201 ALA A N   1 
ATOM   1641 C CA  . ALA A 1 205 ? 3.272   -34.569 9.592   1   28.93  ? 201 ALA A CA  1 
ATOM   1642 C C   . ALA A 1 205 ? 3.521   -35.353 8.304   1   28.03  ? 201 ALA A C   1 
ATOM   1643 O O   . ALA A 1 205 ? 4.505   -36.076 8.22    1   26.95  ? 201 ALA A O   1 
ATOM   1644 C CB  . ALA A 1 205 ? 4.025   -33.263 9.575   1   25.29  ? 201 ALA A CB  1 
ATOM   1645 N N   . LEU A 1 206 ? 2.618   -35.206 7.323   1   24.48  ? 202 LEU A N   1 
ATOM   1646 C CA  . LEU A 1 206 ? 2.701   -35.945 6.079   1   24.07  ? 202 LEU A CA  1 
ATOM   1647 C C   . LEU A 1 206 ? 3.75    -35.317 5.161   1   23.99  ? 202 LEU A C   1 
ATOM   1648 O O   . LEU A 1 206 ? 4.404   -36.02  4.407   1   28.08  ? 202 LEU A O   1 
ATOM   1649 C CB  . LEU A 1 206 ? 1.313   -35.929 5.435   1   22.71  ? 202 LEU A CB  1 
ATOM   1650 C CG  . LEU A 1 206 ? 1.188   -36.688 4.107   1   24.03  ? 202 LEU A CG  1 
ATOM   1651 C CD1 . LEU A 1 206 ? 1.474   -38.17  4.342   1   23.84  ? 202 LEU A CD1 1 
ATOM   1652 C CD2 . LEU A 1 206 ? -0.175  -36.503 3.485   1   22.67  ? 202 LEU A CD2 1 
ATOM   1653 N N   . PHE A 1 207 ? 3.856   -33.986 5.166   1   23.05  ? 203 PHE A N   1 
ATOM   1654 C CA  . PHE A 1 207 ? 4.793   -33.292 4.301   1   22.57  ? 203 PHE A CA  1 
ATOM   1655 C C   . PHE A 1 207 ? 5.564   -32.271 5.136   1   24.15  ? 203 PHE A C   1 
ATOM   1656 O O   . PHE A 1 207 ? 5.21    -31.087 5.146   1   27.66  ? 203 PHE A O   1 
ATOM   1657 C CB  . PHE A 1 207 ? 4       -32.58  3.205   1   22.89  ? 203 PHE A CB  1 
ATOM   1658 C CG  . PHE A 1 207 ? 3.054   -33.453 2.395   1   22.7   ? 203 PHE A CG  1 
ATOM   1659 C CD1 . PHE A 1 207 ? 3.524   -34.571 1.711   1   22.83  ? 203 PHE A CD1 1 
ATOM   1660 C CD2 . PHE A 1 207 ? 1.708   -33.134 2.308   1   23.44  ? 203 PHE A CD2 1 
ATOM   1661 C CE1 . PHE A 1 207 ? 2.683   -35.341 0.938   1   23.84  ? 203 PHE A CE1 1 
ATOM   1662 C CE2 . PHE A 1 207 ? 0.846   -33.925 1.546   1   25.92  ? 203 PHE A CE2 1 
ATOM   1663 C CZ  . PHE A 1 207 ? 1.341   -35.022 0.846   1   24.48  ? 203 PHE A CZ  1 
ATOM   1664 N N   . PRO A 1 208 ? 6.619   -32.694 5.878   1   20.82  ? 204 PRO A N   1 
ATOM   1665 C CA  . PRO A 1 208 ? 7.361   -31.776 6.756   1   20.41  ? 204 PRO A CA  1 
ATOM   1666 C C   . PRO A 1 208 ? 8.493   -31.045 6.048   1   21.24  ? 204 PRO A C   1 
ATOM   1667 O O   . PRO A 1 208 ? 9.662   -31.299 6.347   1   20.56  ? 204 PRO A O   1 
ATOM   1668 C CB  . PRO A 1 208 ? 7.944   -32.724 7.832   1   17.98  ? 204 PRO A CB  1 
ATOM   1669 C CG  . PRO A 1 208 ? 8.153   -34.05  7.094   1   17.02  ? 204 PRO A CG  1 
ATOM   1670 C CD  . PRO A 1 208 ? 7.104   -34.089 5.962   1   18.3   ? 204 PRO A CD  1 
ATOM   1671 N N   . GLY A 1 209 ? 8.153   -30.149 5.122   1   21.43  ? 205 GLY A N   1 
ATOM   1672 C CA  . GLY A 1 209 ? 9.167   -29.449 4.349   1   23.63  ? 205 GLY A CA  1 
ATOM   1673 C C   . GLY A 1 209 ? 9.843   -28.31  5.111   1   25.8   ? 205 GLY A C   1 
ATOM   1674 O O   . GLY A 1 209 ? 9.269   -27.76  6.035   1   27.25  ? 205 GLY A O   1 
ATOM   1675 N N   . ASP A 1 210 ? 11.054  -27.926 4.701   1   29.01  ? 206 ASP A N   1 
ATOM   1676 C CA  . ASP A 1 210 ? 11.751  -26.88  5.44    1   36.51  ? 206 ASP A CA  1 
ATOM   1677 C C   . ASP A 1 210 ? 11.876  -25.615 4.597   1   31.39  ? 206 ASP A C   1 
ATOM   1678 O O   . ASP A 1 210 ? 12.543  -24.676 5.019   1   33.7   ? 206 ASP A O   1 
ATOM   1679 C CB  . ASP A 1 210 ? 12.979  -27.404 6.175   1   41.08  ? 206 ASP A CB  1 
ATOM   1680 C CG  . ASP A 1 210 ? 14.051  -28.006 5.281   1   52.97  ? 206 ASP A CG  1 
ATOM   1681 O OD1 . ASP A 1 210 ? 13.798  -28.085 4.062   1   62.23  ? 206 ASP A OD1 1 
ATOM   1682 O OD2 . ASP A 1 210 ? 15.124  -28.401 5.81    1   49.36  ? 206 ASP A OD2 1 
ATOM   1683 N N   . SER A 1 211 ? 11.148  -25.573 3.472   1   24.68  ? 207 SER A N   1 
ATOM   1684 C CA  . SER A 1 211 ? 11.074  -24.391 2.622   1   22.67  ? 207 SER A CA  1 
ATOM   1685 C C   . SER A 1 211 ? 9.934   -24.56  1.635   1   20.63  ? 207 SER A C   1 
ATOM   1686 O O   . SER A 1 211 ? 9.43    -25.666 1.481   1   22.48  ? 207 SER A O   1 
ATOM   1687 C CB  . SER A 1 211 ? 12.387  -24.144 1.882   1   22.31  ? 207 SER A CB  1 
ATOM   1688 O OG  . SER A 1 211 ? 12.785  -25.315 1.186   1   21.75  ? 207 SER A OG  1 
ATOM   1689 N N   . GLU A 1 212 ? 9.553   -23.487 0.939   1   20.47  ? 208 GLU A N   1 
ATOM   1690 C CA  . GLU A 1 212 ? 8.544   -23.61  -0.1    1   21.35  ? 208 GLU A CA  1 
ATOM   1691 C C   . GLU A 1 212 ? 8.901   -24.725 -1.087  1   19.72  ? 208 GLU A C   1 
ATOM   1692 O O   . GLU A 1 212 ? 8.095   -25.62  -1.311  1   17.39  ? 208 GLU A O   1 
ATOM   1693 C CB  . GLU A 1 212 ? 8.325   -22.278 -0.811  1   26.67  ? 208 GLU A CB  1 
ATOM   1694 C CG  . GLU A 1 212 ? 7.312   -21.353 -0.141  1   35.07  ? 208 GLU A CG  1 
ATOM   1695 C CD  . GLU A 1 212 ? 7.142   -20.024 -0.874  1   43.18  ? 208 GLU A CD  1 
ATOM   1696 O OE1 . GLU A 1 212 ? 6.136   -19.785 -1.601  1   42.34  ? 208 GLU A OE1 1 
ATOM   1697 O OE2 . GLU A 1 212 ? 8.07    -19.199 -0.708  1   54.23  ? 208 GLU A OE2 1 
ATOM   1698 N N   . ILE A 1 213 ? 10.115  -24.697 -1.669  1   20.74  ? 209 ILE A N   1 
ATOM   1699 C CA  . ILE A 1 213 ? 10.471  -25.658 -2.704  1   20.57  ? 209 ILE A CA  1 
ATOM   1700 C C   . ILE A 1 213 ? 10.645  -27.056 -2.111  1   20.81  ? 209 ILE A C   1 
ATOM   1701 O O   . ILE A 1 213 ? 10.325  -28.051 -2.758  1   21.21  ? 209 ILE A O   1 
ATOM   1702 C CB  . ILE A 1 213 ? 11.676  -25.215 -3.567  1   22     ? 209 ILE A CB  1 
ATOM   1703 C CG1 . ILE A 1 213 ? 11.661  -25.859 -4.935  1   23.63  ? 209 ILE A CG1 1 
ATOM   1704 C CG2 . ILE A 1 213 ? 13.018  -25.427 -2.893  1   20.61  ? 209 ILE A CG2 1 
ATOM   1705 C CD1 . ILE A 1 213 ? 10.441  -25.459 -5.773  1   23.09  ? 209 ILE A CD1 1 
ATOM   1706 N N   . ASP A 1 214 ? 11.119  -27.138 -0.864  1   21.65  ? 210 ASP A N   1 
ATOM   1707 C CA  . ASP A 1 214 ? 11.243  -28.434 -0.22   1   21.85  ? 210 ASP A CA  1 
ATOM   1708 C C   . ASP A 1 214 ? 9.882   -29.065 0.055   1   21.09  ? 210 ASP A C   1 
ATOM   1709 O O   . ASP A 1 214 ? 9.728   -30.279 -0.093  1   21.59  ? 210 ASP A O   1 
ATOM   1710 C CB  . ASP A 1 214 ? 12.057  -28.402 1.056   1   24.19  ? 210 ASP A CB  1 
ATOM   1711 C CG  . ASP A 1 214 ? 12.306  -29.801 1.598   1   30.06  ? 210 ASP A CG  1 
ATOM   1712 O OD1 . ASP A 1 214 ? 12.647  -30.692 0.751   1   29.41  ? 210 ASP A OD1 1 
ATOM   1713 O OD2 . ASP A 1 214 ? 12.11   -29.999 2.832   1   29.93  ? 210 ASP A OD2 1 
ATOM   1714 N N   . GLN A 1 215 ? 8.909   -28.236 0.46    1   20.8   ? 211 GLN A N   1 
ATOM   1715 C CA  . GLN A 1 215 ? 7.521   -28.653 0.646   1   21.84  ? 211 GLN A CA  1 
ATOM   1716 C C   . GLN A 1 215 ? 6.975   -29.214 -0.668  1   20.13  ? 211 GLN A C   1 
ATOM   1717 O O   . GLN A 1 215 ? 6.4     -30.291 -0.665  1   22.45  ? 211 GLN A O   1 
ATOM   1718 C CB  . GLN A 1 215 ? 6.676   -27.486 1.176   1   21.92  ? 211 GLN A CB  1 
ATOM   1719 C CG  . GLN A 1 215 ? 5.275   -27.865 1.628   1   20.59  ? 211 GLN A CG  1 
ATOM   1720 C CD  . GLN A 1 215 ? 5.309   -28.732 2.863   1   22.42  ? 211 GLN A CD  1 
ATOM   1721 O OE1 . GLN A 1 215 ? 6.265   -28.69  3.643   1   23.3   ? 211 GLN A OE1 1 
ATOM   1722 N NE2 . GLN A 1 215 ? 4.263   -29.524 3.055   1   23.06  ? 211 GLN A NE2 1 
ATOM   1723 N N   . LEU A 1 216 ? 7.171   -28.514 -1.794  1   19.64  ? 212 LEU A N   1 
ATOM   1724 C CA  . LEU A 1 216 ? 6.647   -28.996 -3.071  1   22.26  ? 212 LEU A CA  1 
ATOM   1725 C C   . LEU A 1 216 ? 7.209   -30.375 -3.377  1   22.14  ? 212 LEU A C   1 
ATOM   1726 O O   . LEU A 1 216 ? 6.447   -31.278 -3.739  1   20.58  ? 212 LEU A O   1 
ATOM   1727 C CB  . LEU A 1 216 ? 7.052   -28.117 -4.252  1   25.34  ? 212 LEU A CB  1 
ATOM   1728 C CG  . LEU A 1 216 ? 6.089   -27.04  -4.737  1   26.17  ? 212 LEU A CG  1 
ATOM   1729 C CD1 . LEU A 1 216 ? 6.73    -26.587 -6.036  1   23.16  ? 212 LEU A CD1 1 
ATOM   1730 C CD2 . LEU A 1 216 ? 4.669   -27.561 -4.953  1   25.49  ? 212 LEU A CD2 1 
ATOM   1731 N N   . PHE A 1 217 ? 8.556   -30.461 -3.304  1   20.19  ? 213 PHE A N   1 
ATOM   1732 C CA  . PHE A 1 217 ? 9.265   -31.668 -3.677  1   19.67  ? 213 PHE A CA  1 
ATOM   1733 C C   . PHE A 1 217 ? 8.708   -32.83  -2.861  1   23.89  ? 213 PHE A C   1 
ATOM   1734 O O   . PHE A 1 217 ? 8.378   -33.855 -3.462  1   28.01  ? 213 PHE A O   1 
ATOM   1735 C CB  . PHE A 1 217 ? 10.783  -31.473 -3.688  1   18.35  ? 213 PHE A CB  1 
ATOM   1736 C CG  . PHE A 1 217 ? 11.281  -30.609 -4.84   1   16.84  ? 213 PHE A CG  1 
ATOM   1737 C CD1 . PHE A 1 217 ? 10.396  -30.027 -5.741  1   15.79  ? 213 PHE A CD1 1 
ATOM   1738 C CD2 . PHE A 1 217 ? 12.63   -30.35  -5      1   16.52  ? 213 PHE A CD2 1 
ATOM   1739 C CE1 . PHE A 1 217 ? 10.866  -29.252 -6.784  1   15.66  ? 213 PHE A CE1 1 
ATOM   1740 C CE2 . PHE A 1 217 ? 13.095  -29.591 -6.071  1   16.41  ? 213 PHE A CE2 1 
ATOM   1741 C CZ  . PHE A 1 217 ? 12.204  -29.034 -6.953  1   15.07  ? 213 PHE A CZ  1 
ATOM   1742 N N   . ARG A 1 218 ? 8.525   -32.638 -1.537  1   22.92  ? 214 ARG A N   1 
ATOM   1743 C CA  . ARG A 1 218 ? 8.013   -33.695 -0.661  1   23.95  ? 214 ARG A CA  1 
ATOM   1744 C C   . ARG A 1 218 ? 6.644   -34.189 -1.131  1   20.5   ? 214 ARG A C   1 
ATOM   1745 O O   . ARG A 1 218 ? 6.4     -35.397 -1.124  1   19.27  ? 214 ARG A O   1 
ATOM   1746 C CB  . ARG A 1 218 ? 7.936   -33.325 0.831   1   22.63  ? 214 ARG A CB  1 
ATOM   1747 C CG  . ARG A 1 218 ? 9.209   -33.629 1.592   1   26.09  ? 214 ARG A CG  1 
ATOM   1748 C CD  . ARG A 1 218 ? 9.565   -32.444 2.469   1   29.42  ? 214 ARG A CD  1 
ATOM   1749 N NE  . ARG A 1 218 ? 10.832  -32.505 3.214   1   29.01  ? 214 ARG A NE  1 
ATOM   1750 C CZ  . ARG A 1 218 ? 11.083  -33.363 4.2     1   27.92  ? 214 ARG A CZ  1 
ATOM   1751 N NH1 . ARG A 1 218 ? 10.193  -34.303 4.503   1   28.96  ? 214 ARG A NH1 1 
ATOM   1752 N NH2 . ARG A 1 218 ? 12.215  -33.265 4.869   1   22.75  ? 214 ARG A NH2 1 
ATOM   1753 N N   . ILE A 1 219 ? 5.775   -33.237 -1.49   1   20.6   ? 215 ILE A N   1 
ATOM   1754 C CA  . ILE A 1 219 ? 4.443   -33.527 -1.996  1   21.7   ? 215 ILE A CA  1 
ATOM   1755 C C   . ILE A 1 219 ? 4.551   -34.331 -3.297  1   23.4   ? 215 ILE A C   1 
ATOM   1756 O O   . ILE A 1 219 ? 3.954   -35.403 -3.406  1   23.14  ? 215 ILE A O   1 
ATOM   1757 C CB  . ILE A 1 219 ? 3.631   -32.236 -2.18   1   21.44  ? 215 ILE A CB  1 
ATOM   1758 C CG1 . ILE A 1 219 ? 3.353   -31.563 -0.836  1   21.66  ? 215 ILE A CG1 1 
ATOM   1759 C CG2 . ILE A 1 219 ? 2.34    -32.549 -2.934  1   19.12  ? 215 ILE A CG2 1 
ATOM   1760 C CD1 . ILE A 1 219 ? 2.709   -30.195 -0.935  1   20.54  ? 215 ILE A CD1 1 
ATOM   1761 N N   . PHE A 1 220 ? 5.366   -33.838 -4.241  1   22.28  ? 216 PHE A N   1 
ATOM   1762 C CA  . PHE A 1 220 ? 5.601   -34.46  -5.538  1   22.2   ? 216 PHE A CA  1 
ATOM   1763 C C   . PHE A 1 220 ? 6.1     -35.901 -5.391  1   21.91  ? 216 PHE A C   1 
ATOM   1764 O O   . PHE A 1 220 ? 5.663   -36.789 -6.128  1   21.98  ? 216 PHE A O   1 
ATOM   1765 C CB  . PHE A 1 220 ? 6.636   -33.669 -6.357  1   18.8   ? 216 PHE A CB  1 
ATOM   1766 C CG  . PHE A 1 220 ? 6.155   -32.341 -6.919  1   17.37  ? 216 PHE A CG  1 
ATOM   1767 C CD1 . PHE A 1 220 ? 4.873   -31.876 -6.641  1   16.22  ? 216 PHE A CD1 1 
ATOM   1768 C CD2 . PHE A 1 220 ? 6.991   -31.571 -7.731  1   17.19  ? 216 PHE A CD2 1 
ATOM   1769 C CE1 . PHE A 1 220 ? 4.44    -30.675 -7.182  1   17.14  ? 216 PHE A CE1 1 
ATOM   1770 C CE2 . PHE A 1 220 ? 6.541   -30.374 -8.29   1   17.62  ? 216 PHE A CE2 1 
ATOM   1771 C CZ  . PHE A 1 220 ? 5.264   -29.925 -8.002  1   16.7   ? 216 PHE A CZ  1 
ATOM   1772 N N   . ARG A 1 221 ? 7.023   -36.12  -4.456  1   19.94  ? 217 ARG A N   1 
ATOM   1773 C CA  . ARG A 1 221 ? 7.626   -37.427 -4.253  1   21.32  ? 217 ARG A CA  1 
ATOM   1774 C C   . ARG A 1 221 ? 6.615   -38.4   -3.648  1   22.24  ? 217 ARG A C   1 
ATOM   1775 O O   . ARG A 1 221 ? 6.805   -39.604 -3.742  1   26.3   ? 217 ARG A O   1 
ATOM   1776 C CB  . ARG A 1 221 ? 8.88    -37.319 -3.371  1   19.28  ? 217 ARG A CB  1 
ATOM   1777 C CG  . ARG A 1 221 ? 10.092  -36.807 -4.124  1   18.83  ? 217 ARG A CG  1 
ATOM   1778 C CD  . ARG A 1 221 ? 11.433  -37.195 -3.5    1   18.72  ? 217 ARG A CD  1 
ATOM   1779 N NE  . ARG A 1 221 ? 11.62   -36.557 -2.194  1   19.74  ? 217 ARG A NE  1 
ATOM   1780 C CZ  . ARG A 1 221 ? 11.977  -35.293 -1.938  1   18.25  ? 217 ARG A CZ  1 
ATOM   1781 N NH1 . ARG A 1 221 ? 11.782  -34.81  -0.72   1   16.2   ? 217 ARG A NH1 1 
ATOM   1782 N NH2 . ARG A 1 221 ? 12.462  -34.527 -2.901  1   17.55  ? 217 ARG A NH2 1 
ATOM   1783 N N   . THR A 1 222 ? 5.556   -37.881 -3.016  1   23     ? 218 THR A N   1 
ATOM   1784 C CA  . THR A 1 222 ? 4.519   -38.692 -2.391  1   23.66  ? 218 THR A CA  1 
ATOM   1785 C C   . THR A 1 222 ? 3.346   -38.967 -3.351  1   25.05  ? 218 THR A C   1 
ATOM   1786 O O   . THR A 1 222 ? 2.796   -40.072 -3.367  1   28.32  ? 218 THR A O   1 
ATOM   1787 C CB  . THR A 1 222 ? 4.053   -38.007 -1.102  1   24.77  ? 218 THR A CB  1 
ATOM   1788 O OG1 . THR A 1 222 ? 5.22    -37.959 -0.292  1   25.9   ? 218 THR A OG1 1 
ATOM   1789 C CG2 . THR A 1 222 ? 2.937   -38.751 -0.384  1   25.43  ? 218 THR A CG2 1 
ATOM   1790 N N   . LEU A 1 223 ? 2.923   -37.967 -4.125  1   20.65  ? 219 LEU A N   1 
ATOM   1791 C CA  . LEU A 1 223 ? 1.743   -38.1   -4.961  1   22.34  ? 219 LEU A CA  1 
ATOM   1792 C C   . LEU A 1 223 ? 2.118   -38.081 -6.44   1   24.07  ? 219 LEU A C   1 
ATOM   1793 O O   . LEU A 1 223 ? 1.233   -38.09  -7.282  1   25.84  ? 219 LEU A O   1 
ATOM   1794 C CB  . LEU A 1 223 ? 0.828   -36.913 -4.653  1   24.48  ? 219 LEU A CB  1 
ATOM   1795 C CG  . LEU A 1 223 ? 0.455   -36.693 -3.181  1   26.16  ? 219 LEU A CG  1 
ATOM   1796 C CD1 . LEU A 1 223 ? -0.509  -35.542 -3.032  1   25.4   ? 219 LEU A CD1 1 
ATOM   1797 C CD2 . LEU A 1 223 ? -0.168  -37.933 -2.555  1   29.75  ? 219 LEU A CD2 1 
ATOM   1798 N N   . GLY A 1 224 ? 3.42    -37.965 -6.742  1   24.62  ? 220 GLY A N   1 
ATOM   1799 C CA  . GLY A 1 224 ? 3.91    -37.817 -8.094  1   20.27  ? 220 GLY A CA  1 
ATOM   1800 C C   . GLY A 1 224 ? 3.969   -36.339 -8.45   1   21.66  ? 220 GLY A C   1 
ATOM   1801 O O   . GLY A 1 224 ? 3.246   -35.514 -7.885  1   23.35  ? 220 GLY A O   1 
ATOM   1802 N N   . THR A 1 225 ? 4.831   -36.016 -9.413  1   20.65  ? 221 THR A N   1 
ATOM   1803 C CA  . THR A 1 225 ? 4.938   -34.656 -9.915  1   22.99  ? 221 THR A CA  1 
ATOM   1804 C C   . THR A 1 225 ? 3.763   -34.443 -10.858 1   23.99  ? 221 THR A C   1 
ATOM   1805 O O   . THR A 1 225 ? 3.591   -35.192 -11.798 1   26.52  ? 221 THR A O   1 
ATOM   1806 C CB  . THR A 1 225 ? 6.273   -34.441 -10.641 1   23.99  ? 221 THR A CB  1 
ATOM   1807 O OG1 . THR A 1 225 ? 7.379   -34.746 -9.792  1   26.75  ? 221 THR A OG1 1 
ATOM   1808 C CG2 . THR A 1 225 ? 6.429   -33.027 -11.164 1   22.82  ? 221 THR A CG2 1 
ATOM   1809 N N   . PRO A 1 226 ? 2.909   -33.428 -10.651 1   26.74  ? 222 PRO A N   1 
ATOM   1810 C CA  . PRO A 1 226 ? 1.721   -33.272 -11.498 1   26.78  ? 222 PRO A CA  1 
ATOM   1811 C C   . PRO A 1 226 ? 2.048   -32.727 -12.891 1   27.13  ? 222 PRO A C   1 
ATOM   1812 O O   . PRO A 1 226 ? 2.99    -31.957 -13.069 1   28.97  ? 222 PRO A O   1 
ATOM   1813 C CB  . PRO A 1 226 ? 0.888   -32.302 -10.634 1   26.75  ? 222 PRO A CB  1 
ATOM   1814 C CG  . PRO A 1 226 ? 1.946   -31.43  -9.952  1   26.11  ? 222 PRO A CG  1 
ATOM   1815 C CD  . PRO A 1 226 ? 3.059   -32.391 -9.616  1   26.23  ? 222 PRO A CD  1 
ATOM   1816 N N   . ASP A 1 227 ? 1.288   -33.182 -13.892 1   29.13  ? 223 ASP A N   1 
ATOM   1817 C CA  . ASP A 1 227 ? 1.42    -32.733 -15.276 1   30.01  ? 223 ASP A CA  1 
ATOM   1818 C C   . ASP A 1 227 ? 0.036   -32.282 -15.742 1   27.25  ? 223 ASP A C   1 
ATOM   1819 O O   . ASP A 1 227 ? -0.868  -32.209 -14.923 1   24.94  ? 223 ASP A O   1 
ATOM   1820 C CB  . ASP A 1 227 ? 1.99    -33.835 -16.155 1   28.05  ? 223 ASP A CB  1 
ATOM   1821 C CG  . ASP A 1 227 ? 1.119   -35.079 -16.17  1   34.1   ? 223 ASP A CG  1 
ATOM   1822 O OD1 . ASP A 1 227 ? -0.112  -34.944 -15.966 1   34.49  ? 223 ASP A OD1 1 
ATOM   1823 O OD2 . ASP A 1 227 ? 1.673   -36.171 -16.369 1   40.92  ? 223 ASP A OD2 1 
ATOM   1824 N N   . GLU A 1 228 ? -0.128  -32.025 -17.048 1   29.83  ? 224 GLU A N   1 
ATOM   1825 C CA  . GLU A 1 228 ? -1.321  -31.377 -17.585 1   32.36  ? 224 GLU A CA  1 
ATOM   1826 C C   . GLU A 1 228 ? -2.535  -32.304 -17.51  1   30.64  ? 224 GLU A C   1 
ATOM   1827 O O   . GLU A 1 228 ? -3.665  -31.824 -17.375 1   34.09  ? 224 GLU A O   1 
ATOM   1828 C CB  . GLU A 1 228 ? -1.026  -30.81  -18.976 1   29.99  ? 224 GLU A CB  1 
ATOM   1829 C CG  . GLU A 1 228 ? -0.234  -29.51  -18.911 1   30.3   ? 224 GLU A CG  1 
ATOM   1830 C CD  . GLU A 1 228 ? -0.992  -28.289 -18.388 1   38.67  ? 224 GLU A CD  1 
ATOM   1831 O OE1 . GLU A 1 228 ? -2.263  -28.218 -18.416 1   37.31  ? 224 GLU A OE1 1 
ATOM   1832 O OE2 . GLU A 1 228 ? -0.271  -27.382 -17.901 1   39.38  ? 224 GLU A OE2 1 
ATOM   1833 N N   . VAL A 1 229 ? -2.268  -33.618 -17.515 1   27.72  ? 225 VAL A N   1 
ATOM   1834 C CA  . VAL A 1 229 ? -3.298  -34.644 -17.418 1   27.96  ? 225 VAL A CA  1 
ATOM   1835 C C   . VAL A 1 229 ? -3.914  -34.661 -16.021 1   29.71  ? 225 VAL A C   1 
ATOM   1836 O O   . VAL A 1 229 ? -5.123  -34.681 -15.871 1   32.33  ? 225 VAL A O   1 
ATOM   1837 C CB  . VAL A 1 229 ? -2.775  -36.055 -17.737 1   28.72  ? 225 VAL A CB  1 
ATOM   1838 C CG1 . VAL A 1 229 ? -3.924  -37.054 -17.704 1   27.7   ? 225 VAL A CG1 1 
ATOM   1839 C CG2 . VAL A 1 229 ? -2.027  -36.105 -19.067 1   26.26  ? 225 VAL A CG2 1 
ATOM   1840 N N   . VAL A 1 230 ? -3.092  -34.742 -14.981 1   27.23  ? 226 VAL A N   1 
ATOM   1841 C CA  . VAL A 1 230 ? -3.67   -34.816 -13.662 1   28.4   ? 226 VAL A CA  1 
ATOM   1842 C C   . VAL A 1 230 ? -4.127  -33.419 -13.253 1   28.06  ? 226 VAL A C   1 
ATOM   1843 O O   . VAL A 1 230 ? -5.101  -33.267 -12.516 1   27.89  ? 226 VAL A O   1 
ATOM   1844 C CB  . VAL A 1 230 ? -2.687  -35.476 -12.677 1   34.64  ? 226 VAL A CB  1 
ATOM   1845 C CG1 . VAL A 1 230 ? -1.324  -34.809 -12.732 1   40.71  ? 226 VAL A CG1 1 
ATOM   1846 C CG2 . VAL A 1 230 ? -3.219  -35.499 -11.253 1   35.27  ? 226 VAL A CG2 1 
ATOM   1847 N N   . TRP A 1 231 ? -3.473  -32.381 -13.778 1   27.01  ? 227 TRP A N   1 
ATOM   1848 C CA  . TRP A 1 231 ? -3.82   -31.05  -13.302 1   30.59  ? 227 TRP A CA  1 
ATOM   1849 C C   . TRP A 1 231 ? -3.694  -30.034 -14.428 1   30.47  ? 227 TRP A C   1 
ATOM   1850 O O   . TRP A 1 231 ? -2.642  -29.439 -14.627 1   31.86  ? 227 TRP A O   1 
ATOM   1851 C CB  . TRP A 1 231 ? -2.977  -30.701 -12.067 1   33.22  ? 227 TRP A CB  1 
ATOM   1852 C CG  . TRP A 1 231 ? -3.278  -29.387 -11.403 1   34.9   ? 227 TRP A CG  1 
ATOM   1853 C CD1 . TRP A 1 231 ? -4.29   -28.519 -11.675 1   31.3   ? 227 TRP A CD1 1 
ATOM   1854 C CD2 . TRP A 1 231 ? -2.516  -28.804 -10.323 1   33.79  ? 227 TRP A CD2 1 
ATOM   1855 N NE1 . TRP A 1 231 ? -4.203  -27.436 -10.847 1   35.11  ? 227 TRP A NE1 1 
ATOM   1856 C CE2 . TRP A 1 231 ? -3.131  -27.58  -10.007 1   32.26  ? 227 TRP A CE2 1 
ATOM   1857 C CE3 . TRP A 1 231 ? -1.38   -29.202 -9.607  1   34.62  ? 227 TRP A CE3 1 
ATOM   1858 C CZ2 . TRP A 1 231 ? -2.662  -26.749 -8.997  1   32.36  ? 227 TRP A CZ2 1 
ATOM   1859 C CZ3 . TRP A 1 231 ? -0.896  -28.374 -8.622  1   37.53  ? 227 TRP A CZ3 1 
ATOM   1860 C CH2 . TRP A 1 231 ? -1.541  -27.171 -8.316  1   40.71  ? 227 TRP A CH2 1 
ATOM   1861 N N   . PRO A 1 232 ? -4.773  -29.815 -15.203 1   33.66  ? 228 PRO A N   1 
ATOM   1862 C CA  . PRO A 1 232 ? -4.737  -28.833 -16.295 1   34.9   ? 228 PRO A CA  1 
ATOM   1863 C C   . PRO A 1 232 ? -4.46   -27.427 -15.743 1   32.06  ? 228 PRO A C   1 
ATOM   1864 O O   . PRO A 1 232 ? -5.119  -26.984 -14.798 1   27.37  ? 228 PRO A O   1 
ATOM   1865 C CB  . PRO A 1 232 ? -6.108  -28.956 -17.044 1   31.3   ? 228 PRO A CB  1 
ATOM   1866 C CG  . PRO A 1 232 ? -6.797  -30.154 -16.377 1   34.04  ? 228 PRO A CG  1 
ATOM   1867 C CD  . PRO A 1 232 ? -6.075  -30.497 -15.066 1   33.91  ? 228 PRO A CD  1 
ATOM   1868 N N   . GLY A 1 233 ? -3.449  -26.753 -16.32  1   31.73  ? 229 GLY A N   1 
ATOM   1869 C CA  . GLY A 1 233 ? -3.013  -25.445 -15.851 1   33.91  ? 229 GLY A CA  1 
ATOM   1870 C C   . GLY A 1 233 ? -1.665  -25.47  -15.119 1   35.61  ? 229 GLY A C   1 
ATOM   1871 O O   . GLY A 1 233 ? -0.931  -24.482 -15.135 1   39.19  ? 229 GLY A O   1 
ATOM   1872 N N   . VAL A 1 234 ? -1.343  -26.606 -14.491 1   31.42  ? 230 VAL A N   1 
ATOM   1873 C CA  . VAL A 1 234 ? -0.241  -26.701 -13.556 1   30.8   ? 230 VAL A CA  1 
ATOM   1874 C C   . VAL A 1 234 ? 1.01    -26.085 -14.186 1   34.79  ? 230 VAL A C   1 
ATOM   1875 O O   . VAL A 1 234 ? 1.66    -25.244 -13.571 1   37.53  ? 230 VAL A O   1 
ATOM   1876 C CB  . VAL A 1 234 ? -0.023  -28.132 -13.024 1   27.21  ? 230 VAL A CB  1 
ATOM   1877 C CG1 . VAL A 1 234 ? 0.505   -29.074 -14.093 1   24.69  ? 230 VAL A CG1 1 
ATOM   1878 C CG2 . VAL A 1 234 ? 0.914   -28.147 -11.83  1   25.36  ? 230 VAL A CG2 1 
ATOM   1879 N N   . THR A 1 235 ? 1.32    -26.455 -15.433 1   33.9   ? 231 THR A N   1 
ATOM   1880 C CA  . THR A 1 235 ? 2.586   -26.03  -16.02  1   33.53  ? 231 THR A CA  1 
ATOM   1881 C C   . THR A 1 235 ? 2.532   -24.552 -16.408 1   35.35  ? 231 THR A C   1 
ATOM   1882 O O   . THR A 1 235 ? 3.553   -23.999 -16.822 1   38.99  ? 231 THR A O   1 
ATOM   1883 C CB  . THR A 1 235 ? 3.036   -26.872 -17.217 1   27.2   ? 231 THR A CB  1 
ATOM   1884 O OG1 . THR A 1 235 ? 2.145   -26.449 -18.238 1   28.02  ? 231 THR A OG1 1 
ATOM   1885 C CG2 . THR A 1 235 ? 3.014   -28.37  -16.984 1   23.13  ? 231 THR A CG2 1 
ATOM   1886 N N   . SER A 1 236 ? 1.357   -23.924 -16.296 1   33.01  ? 232 SER A N   1 
ATOM   1887 C CA  . SER A 1 236 ? 1.219   -22.521 -16.671 1   39.19  ? 232 SER A CA  1 
ATOM   1888 C C   . SER A 1 236 ? 1.257   -21.653 -15.424 1   39.24  ? 232 SER A C   1 
ATOM   1889 O O   . SER A 1 236 ? 1.174   -20.435 -15.512 1   39.52  ? 232 SER A O   1 
ATOM   1890 C CB  . SER A 1 236 ? -0.053  -22.253 -17.451 1   43.21  ? 232 SER A CB  1 
ATOM   1891 O OG  . SER A 1 236 ? 0.135   -22.607 -18.815 1   49.07  ? 232 SER A OG  1 
ATOM   1892 N N   . MET A 1 237 ? 1.393   -22.302 -14.271 1   39.26  ? 233 MET A N   1 
ATOM   1893 C CA  . MET A 1 237 ? 1.377   -21.623 -12.989 1   38.48  ? 233 MET A CA  1 
ATOM   1894 C C   . MET A 1 237 ? 2.645   -20.813 -12.735 1   34.27  ? 233 MET A C   1 
ATOM   1895 O O   . MET A 1 237 ? 3.726   -21.215 -13.166 1   33.28  ? 233 MET A O   1 
ATOM   1896 C CB  . MET A 1 237 ? 1.04    -22.611 -11.879 1   41.68  ? 233 MET A CB  1 
ATOM   1897 C CG  . MET A 1 237 ? -0.439  -22.613 -11.709 1   46.3   ? 233 MET A CG  1 
ATOM   1898 S SD  . MET A 1 237 ? -1.129  -24.195 -11.241 1   59.52  ? 233 MET A SD  1 
ATOM   1899 C CE  . MET A 1 237 ? 0.033   -24.594 -9.934  1   73.68  ? 233 MET A CE  1 
ATOM   1900 N N   . PRO A 1 238 ? 2.52    -19.65  -12.038 1   32.15  ? 234 PRO A N   1 
ATOM   1901 C CA  . PRO A 1 238 ? 3.571   -18.632 -12.01  1   29.36  ? 234 PRO A CA  1 
ATOM   1902 C C   . PRO A 1 238 ? 4.939   -19.085 -11.509 1   29.49  ? 234 PRO A C   1 
ATOM   1903 O O   . PRO A 1 238 ? 5.96    -18.58  -11.995 1   33.08  ? 234 PRO A O   1 
ATOM   1904 C CB  . PRO A 1 238 ? 2.978   -17.514 -11.127 1   28.73  ? 234 PRO A CB  1 
ATOM   1905 C CG  . PRO A 1 238 ? 1.483   -17.736 -11.177 1   28.86  ? 234 PRO A CG  1 
ATOM   1906 C CD  . PRO A 1 238 ? 1.348   -19.247 -11.23  1   29.18  ? 234 PRO A CD  1 
ATOM   1907 N N   . ASP A 1 239 ? 4.937   -20.027 -10.549 1   26.51  ? 235 ASP A N   1 
ATOM   1908 C CA  . ASP A 1 239 ? 6.157   -20.576 -9.977  1   26.08  ? 235 ASP A CA  1 
ATOM   1909 C C   . ASP A 1 239 ? 6.341   -22.049 -10.345 1   27.76  ? 235 ASP A C   1 
ATOM   1910 O O   . ASP A 1 239 ? 7.135   -22.732 -9.697  1   28.53  ? 235 ASP A O   1 
ATOM   1911 C CB  . ASP A 1 239 ? 6.259   -20.302 -8.482  1   24.02  ? 235 ASP A CB  1 
ATOM   1912 C CG  . ASP A 1 239 ? 6.078   -18.844 -8.094  1   24.81  ? 235 ASP A CG  1 
ATOM   1913 O OD1 . ASP A 1 239 ? 6.473   -17.974 -8.874  1   26.75  ? 235 ASP A OD1 1 
ATOM   1914 O OD2 . ASP A 1 239 ? 5.511   -18.582 -7.028  1   26.36  ? 235 ASP A OD2 1 
ATOM   1915 N N   . TYR A 1 240 ? 5.615   -22.529 -11.369 1   27.32  ? 236 TYR A N   1 
ATOM   1916 C CA  . TYR A 1 240 ? 5.882   -23.824 -11.988 1   28.52  ? 236 TYR A CA  1 
ATOM   1917 C C   . TYR A 1 240 ? 7.117   -23.674 -12.881 1   25.12  ? 236 TYR A C   1 
ATOM   1918 O O   . TYR A 1 240 ? 7.218   -22.728 -13.66  1   23.26  ? 236 TYR A O   1 
ATOM   1919 C CB  . TYR A 1 240 ? 4.734   -24.431 -12.821 1   31.3   ? 236 TYR A CB  1 
ATOM   1920 C CG  . TYR A 1 240 ? 5.099   -25.776 -13.444 1   36.49  ? 236 TYR A CG  1 
ATOM   1921 C CD1 . TYR A 1 240 ? 4.977   -26.967 -12.727 1   40.96  ? 236 TYR A CD1 1 
ATOM   1922 C CD2 . TYR A 1 240 ? 5.687   -25.852 -14.705 1   40.6   ? 236 TYR A CD2 1 
ATOM   1923 C CE1 . TYR A 1 240 ? 5.377   -28.189 -13.258 1   42.41  ? 236 TYR A CE1 1 
ATOM   1924 C CE2 . TYR A 1 240 ? 6.094   -27.065 -15.247 1   40.78  ? 236 TYR A CE2 1 
ATOM   1925 C CZ  . TYR A 1 240 ? 5.947   -28.238 -14.522 1   43.17  ? 236 TYR A CZ  1 
ATOM   1926 O OH  . TYR A 1 240 ? 6.34    -29.422 -15.088 1   44.01  ? 236 TYR A OH  1 
ATOM   1927 N N   . LYS A 1 241 ? 8.032   -24.635 -12.779 1   22.96  ? 237 LYS A N   1 
ATOM   1928 C CA  . LYS A 1 241 ? 9.237   -24.642 -13.589 1   22.87  ? 237 LYS A CA  1 
ATOM   1929 C C   . LYS A 1 241 ? 9.305   -25.977 -14.331 1   20.85  ? 237 LYS A C   1 
ATOM   1930 O O   . LYS A 1 241 ? 9.034   -27.02  -13.745 1   19.65  ? 237 LYS A O   1 
ATOM   1931 C CB  . LYS A 1 241 ? 10.436  -24.314 -12.686 1   24.85  ? 237 LYS A CB  1 
ATOM   1932 C CG  . LYS A 1 241 ? 10.48   -22.844 -12.249 1   30.51  ? 237 LYS A CG  1 
ATOM   1933 C CD  . LYS A 1 241 ? 11.166  -22.59  -10.916 1   36.57  ? 237 LYS A CD  1 
ATOM   1934 C CE  . LYS A 1 241 ? 12.592  -22.908 -11.118 1   41.71  ? 237 LYS A CE  1 
ATOM   1935 N NZ  . LYS A 1 241 ? 13.13   -21.908 -12.045 1   48.18  ? 237 LYS A NZ  1 
ATOM   1936 N N   . PRO A 1 242 ? 9.579   -25.96  -15.658 1   19.82  ? 238 PRO A N   1 
ATOM   1937 C CA  . PRO A 1 242 ? 9.838   -27.17  -16.447 1   19.35  ? 238 PRO A CA  1 
ATOM   1938 C C   . PRO A 1 242 ? 10.913  -28.123 -15.905 1   19.25  ? 238 PRO A C   1 
ATOM   1939 O O   . PRO A 1 242 ? 10.827  -29.338 -16.111 1   18.37  ? 238 PRO A O   1 
ATOM   1940 C CB  . PRO A 1 242 ? 10.217  -26.662 -17.866 1   17.78  ? 238 PRO A CB  1 
ATOM   1941 C CG  . PRO A 1 242 ? 10.1    -25.144 -17.857 1   18.19  ? 238 PRO A CG  1 
ATOM   1942 C CD  . PRO A 1 242 ? 9.656   -24.736 -16.463 1   19.22  ? 238 PRO A CD  1 
ATOM   1943 N N   . SER A 1 243 ? 11.898  -27.546 -15.191 1   18.14  ? 239 SER A N   1 
ATOM   1944 C CA  . SER A 1 243 ? 13.044  -28.235 -14.609 1   17.74  ? 239 SER A CA  1 
ATOM   1945 C C   . SER A 1 243 ? 12.65   -29.103 -13.406 1   16.42  ? 239 SER A C   1 
ATOM   1946 O O   . SER A 1 243 ? 13.45   -29.924 -12.975 1   15.02  ? 239 SER A O   1 
ATOM   1947 C CB  . SER A 1 243 ? 14.119  -27.236 -14.224 1   17.51  ? 239 SER A CB  1 
ATOM   1948 O OG  . SER A 1 243 ? 13.591  -26.287 -13.299 1   19.56  ? 239 SER A OG  1 
ATOM   1949 N N   . PHE A 1 244 ? 11.445  -28.912 -12.858 1   15.48  ? 240 PHE A N   1 
ATOM   1950 C CA  . PHE A 1 244 ? 10.965  -29.719 -11.747 1   17.16  ? 240 PHE A CA  1 
ATOM   1951 C C   . PHE A 1 244 ? 11.19   -31.204 -12.003 1   17.86  ? 240 PHE A C   1 
ATOM   1952 O O   . PHE A 1 244 ? 10.81   -31.731 -13.044 1   18.41  ? 240 PHE A O   1 
ATOM   1953 C CB  . PHE A 1 244 ? 9.465   -29.568 -11.508 1   17.35  ? 240 PHE A CB  1 
ATOM   1954 C CG  . PHE A 1 244 ? 9.064   -28.334 -10.712 1   19.68  ? 240 PHE A CG  1 
ATOM   1955 C CD1 . PHE A 1 244 ? 10.015  -27.522 -10.092 1   19.56  ? 240 PHE A CD1 1 
ATOM   1956 C CD2 . PHE A 1 244 ? 7.714   -28.022 -10.548 1   20.42  ? 240 PHE A CD2 1 
ATOM   1957 C CE1 . PHE A 1 244 ? 9.615   -26.418 -9.346  1   20.02  ? 240 PHE A CE1 1 
ATOM   1958 C CE2 . PHE A 1 244 ? 7.32    -26.915 -9.822  1   19.99  ? 240 PHE A CE2 1 
ATOM   1959 C CZ  . PHE A 1 244 ? 8.268   -26.128 -9.199  1   19.03  ? 240 PHE A CZ  1 
ATOM   1960 N N   . PRO A 1 245 ? 11.787  -31.943 -11.048 1   19.52  ? 241 PRO A N   1 
ATOM   1961 C CA  . PRO A 1 245 ? 11.963  -33.385 -11.213 1   20.91  ? 241 PRO A CA  1 
ATOM   1962 C C   . PRO A 1 245 ? 10.599  -34.032 -11.391 1   21.28  ? 241 PRO A C   1 
ATOM   1963 O O   . PRO A 1 245 ? 9.598   -33.561 -10.857 1   20.5   ? 241 PRO A O   1 
ATOM   1964 C CB  . PRO A 1 245 ? 12.657  -33.821 -9.907  1   22.15  ? 241 PRO A CB  1 
ATOM   1965 C CG  . PRO A 1 245 ? 13.35   -32.552 -9.441  1   22.5   ? 241 PRO A CG  1 
ATOM   1966 C CD  . PRO A 1 245 ? 12.333  -31.447 -9.768  1   21.34  ? 241 PRO A CD  1 
ATOM   1967 N N   . LYS A 1 246 ? 10.581  -35.113 -12.163 1   24.51  ? 242 LYS A N   1 
ATOM   1968 C CA  . LYS A 1 246 ? 9.35    -35.808 -12.5   1   27.31  ? 242 LYS A CA  1 
ATOM   1969 C C   . LYS A 1 246 ? 9.294   -37.089 -11.681 1   25.88  ? 242 LYS A C   1 
ATOM   1970 O O   . LYS A 1 246 ? 9.842   -38.092 -12.106 1   28.53  ? 242 LYS A O   1 
ATOM   1971 C CB  . LYS A 1 246 ? 9.241   -36.051 -14.016 1   27.49  ? 242 LYS A CB  1 
ATOM   1972 C CG  . LYS A 1 246 ? 8.606   -34.884 -14.757 1   32.59  ? 242 LYS A CG  1 
ATOM   1973 C CD  . LYS A 1 246 ? 8.626   -35.046 -16.274 1   43.91  ? 242 LYS A CD  1 
ATOM   1974 C CE  . LYS A 1 246 ? 8.005   -33.913 -17.038 1   44.72  ? 242 LYS A CE  1 
ATOM   1975 N NZ  . LYS A 1 246 ? 8.684   -32.676 -16.649 1   49     ? 242 LYS A NZ  1 
ATOM   1976 N N   . TRP A 1 247 ? 8.661   -37.043 -10.502 1   23.16  ? 243 TRP A N   1 
ATOM   1977 C CA  . TRP A 1 247 ? 8.591   -38.232 -9.667  1   22.7   ? 243 TRP A CA  1 
ATOM   1978 C C   . TRP A 1 247 ? 7.326   -39.008 -10.012 1   22.71  ? 243 TRP A C   1 
ATOM   1979 O O   . TRP A 1 247 ? 6.281   -38.411 -10.244 1   21.13  ? 243 TRP A O   1 
ATOM   1980 C CB  . TRP A 1 247 ? 8.635   -37.86  -8.178  1   21.96  ? 243 TRP A CB  1 
ATOM   1981 C CG  . TRP A 1 247 ? 9.998   -37.477 -7.653  1   21.31  ? 243 TRP A CG  1 
ATOM   1982 C CD1 . TRP A 1 247 ? 11.03   -38.313 -7.341  1   21.34  ? 243 TRP A CD1 1 
ATOM   1983 C CD2 . TRP A 1 247 ? 10.455  -36.147 -7.32   1   21.66  ? 243 TRP A CD2 1 
ATOM   1984 N NE1 . TRP A 1 247 ? 12.105  -37.604 -6.867  1   20.91  ? 243 TRP A NE1 1 
ATOM   1985 C CE2 . TRP A 1 247 ? 11.776  -36.274 -6.831  1   21.24  ? 243 TRP A CE2 1 
ATOM   1986 C CE3 . TRP A 1 247 ? 9.886   -34.866 -7.39   1   21.92  ? 243 TRP A CE3 1 
ATOM   1987 C CZ2 . TRP A 1 247 ? 12.518  -35.17  -6.413  1   20.32  ? 243 TRP A CZ2 1 
ATOM   1988 C CZ3 . TRP A 1 247 ? 10.618  -33.775 -6.962  1   22.01  ? 243 TRP A CZ3 1 
ATOM   1989 C CH2 . TRP A 1 247 ? 11.923  -33.929 -6.486  1   21.13  ? 243 TRP A CH2 1 
ATOM   1990 N N   . ALA A 1 248 ? 7.416   -40.342 -10.034 1   25.01  ? 244 ALA A N   1 
ATOM   1991 C CA  . ALA A 1 248 ? 6.232   -41.153 -10.273 1   25.87  ? 244 ALA A CA  1 
ATOM   1992 C C   . ALA A 1 248 ? 5.382   -41.202 -9.009  1   28.45  ? 244 ALA A C   1 
ATOM   1993 O O   . ALA A 1 248 ? 5.895   -41.207 -7.891  1   30.78  ? 244 ALA A O   1 
ATOM   1994 C CB  . ALA A 1 248 ? 6.616   -42.53  -10.718 1   22.68  ? 244 ALA A CB  1 
ATOM   1995 N N   . ARG A 1 249 ? 4.065   -41.213 -9.212  1   30.62  ? 245 ARG A N   1 
ATOM   1996 C CA  . ARG A 1 249 ? 3.116   -41.351 -8.122  1   32.32  ? 245 ARG A CA  1 
ATOM   1997 C C   . ARG A 1 249 ? 3.268   -42.761 -7.562  1   33.52  ? 245 ARG A C   1 
ATOM   1998 O O   . ARG A 1 249 ? 3.165   -43.751 -8.285  1   32.55  ? 245 ARG A O   1 
ATOM   1999 C CB  . ARG A 1 249 ? 1.721   -41.113 -8.701  1   29.47  ? 245 ARG A CB  1 
ATOM   2000 C CG  . ARG A 1 249 ? 0.64    -41.308 -7.657  1   34.46  ? 245 ARG A CG  1 
ATOM   2001 C CD  . ARG A 1 249 ? -0.711  -40.91  -8.243  1   33.41  ? 245 ARG A CD  1 
ATOM   2002 N NE  . ARG A 1 249 ? -1.698  -41.056 -7.17   1   37.11  ? 245 ARG A NE  1 
ATOM   2003 C CZ  . ARG A 1 249 ? -2.138  -40.057 -6.404  1   40.72  ? 245 ARG A CZ  1 
ATOM   2004 N NH1 . ARG A 1 249 ? -1.525  -38.873 -6.441  1   33.6   ? 245 ARG A NH1 1 
ATOM   2005 N NH2 . ARG A 1 249 ? -3.162  -40.278 -5.582  1   39.47  ? 245 ARG A NH2 1 
ATOM   2006 N N   . GLN A 1 250 ? 3.602   -42.861 -6.279  1   40.23  ? 246 GLN A N   1 
ATOM   2007 C CA  . GLN A 1 250 ? 3.612   -44.188 -5.686  1   39.32  ? 246 GLN A CA  1 
ATOM   2008 C C   . GLN A 1 250 ? 2.164   -44.529 -5.333  1   43.04  ? 246 GLN A C   1 
ATOM   2009 O O   . GLN A 1 250 ? 1.301   -43.634 -5.233  1   40.64  ? 246 GLN A O   1 
ATOM   2010 C CB  . GLN A 1 250 ? 4.467   -44.185 -4.428  1   35.15  ? 246 GLN A CB  1 
ATOM   2011 C CG  . GLN A 1 250 ? 3.788   -43.427 -3.298  1   35.46  ? 246 GLN A CG  1 
ATOM   2012 C CD  . GLN A 1 250 ? 4.74    -43.254 -2.147  1   41.27  ? 246 GLN A CD  1 
ATOM   2013 O OE1 . GLN A 1 250 ? 4.785   -42.208 -1.499  1   45.42  ? 246 GLN A OE1 1 
ATOM   2014 N NE2 . GLN A 1 250 ? 5.549   -44.276 -1.917  1   46.82  ? 246 GLN A NE2 1 
ATOM   2015 N N   . ASP A 1 251 ? 1.93    -45.839 -5.184  1   41.41  ? 247 ASP A N   1 
ATOM   2016 C CA  . ASP A 1 251 ? 0.635   -46.377 -4.811  1   43.8   ? 247 ASP A CA  1 
ATOM   2017 C C   . ASP A 1 251 ? 0.223   -45.782 -3.464  1   36.82  ? 247 ASP A C   1 
ATOM   2018 O O   . ASP A 1 251 ? 1.005   -45.71  -2.522  1   38.13  ? 247 ASP A O   1 
ATOM   2019 C CB  . ASP A 1 251 ? 0.609   -47.889 -5.022  1   54.01  ? 247 ASP A CB  1 
ATOM   2020 C CG  . ASP A 1 251 ? -0.386  -48.683 -4.18   1   71.72  ? 247 ASP A CG  1 
ATOM   2021 O OD1 . ASP A 1 251 ? -1.579  -48.281 -4.122  1   71.74  ? 247 ASP A OD1 1 
ATOM   2022 O OD2 . ASP A 1 251 ? 0.038   -49.717 -3.596  1   86.34  ? 247 ASP A OD2 1 
ATOM   2023 N N   . PHE A 1 252 ? -1.033  -45.361 -3.382  1   33.4   ? 248 PHE A N   1 
ATOM   2024 C CA  . PHE A 1 252 ? -1.55   -44.607 -2.254  1   35.52  ? 248 PHE A CA  1 
ATOM   2025 C C   . PHE A 1 252 ? -1.556  -45.413 -0.945  1   34.27  ? 248 PHE A C   1 
ATOM   2026 O O   . PHE A 1 252 ? -1.565  -44.854 0.152   1   37.35  ? 248 PHE A O   1 
ATOM   2027 C CB  . PHE A 1 252 ? -2.942  -44.102 -2.662  1   37.12  ? 248 PHE A CB  1 
ATOM   2028 C CG  . PHE A 1 252 ? -3.206  -42.764 -1.995  1   36.67  ? 248 PHE A CG  1 
ATOM   2029 C CD1 . PHE A 1 252 ? -2.688  -41.598 -2.558  1   38.92  ? 248 PHE A CD1 1 
ATOM   2030 C CD2 . PHE A 1 252 ? -3.868  -42.675 -0.783  1   33.18  ? 248 PHE A CD2 1 
ATOM   2031 C CE1 . PHE A 1 252 ? -2.866  -40.363 -1.964  1   33.28  ? 248 PHE A CE1 1 
ATOM   2032 C CE2 . PHE A 1 252 ? -4.038  -41.43  -0.193  1   36.29  ? 248 PHE A CE2 1 
ATOM   2033 C CZ  . PHE A 1 252 ? -3.536  -40.284 -0.78   1   32.28  ? 248 PHE A CZ  1 
ATOM   2034 N N   . SER A 1 253 ? -1.619  -46.738 -1.054  1   30.03  ? 249 SER A N   1 
ATOM   2035 C CA  . SER A 1 253 ? -1.568  -47.604 0.109   1   25.6   ? 249 SER A CA  1 
ATOM   2036 C C   . SER A 1 253 ? -0.217  -47.529 0.832   1   26.86  ? 249 SER A C   1 
ATOM   2037 O O   . SER A 1 253 ? -0.062  -48.096 1.923   1   26.1   ? 249 SER A O   1 
ATOM   2038 C CB  . SER A 1 253 ? -1.866  -49.018 -0.325  1   23.7   ? 249 SER A CB  1 
ATOM   2039 O OG  . SER A 1 253 ? -0.787  -49.552 -1.086  1   24.67  ? 249 SER A OG  1 
ATOM   2040 N N   . LYS A 1 254 ? 0.78    -46.904 0.183   1   28.18  ? 250 LYS A N   1 
ATOM   2041 C CA  . LYS A 1 254 ? 2.13    -46.801 0.719   1   29.76  ? 250 LYS A CA  1 
ATOM   2042 C C   . LYS A 1 254 ? 2.276   -45.483 1.475   1   31.22  ? 250 LYS A C   1 
ATOM   2043 O O   . LYS A 1 254 ? 3.145   -45.372 2.327   1   35.68  ? 250 LYS A O   1 
ATOM   2044 C CB  . LYS A 1 254 ? 3.192   -46.979 -0.373  1   28.25  ? 250 LYS A CB  1 
ATOM   2045 C CG  . LYS A 1 254 ? 3.241   -48.377 -0.962  1   27.4   ? 250 LYS A CG  1 
ATOM   2046 C CD  . LYS A 1 254 ? 3.691   -49.446 0.033   1   33.82  ? 250 LYS A CD  1 
ATOM   2047 C CE  . LYS A 1 254 ? 3.6     -50.879 -0.447  1   35.73  ? 250 LYS A CE  1 
ATOM   2048 N NZ  . LYS A 1 254 ? 2.196   -51.266 -0.635  1   40.14  ? 250 LYS A NZ  1 
ATOM   2049 N N   . VAL A 1 255 ? 1.379   -44.527 1.199   1   29.91  ? 251 VAL A N   1 
ATOM   2050 C CA  . VAL A 1 255 ? 1.437   -43.201 1.782   1   30.08  ? 251 VAL A CA  1 
ATOM   2051 C C   . VAL A 1 255 ? 1.045   -43.269 3.252   1   33.64  ? 251 VAL A C   1 
ATOM   2052 O O   . VAL A 1 255 ? 1.684   -42.617 4.084   1   38.55  ? 251 VAL A O   1 
ATOM   2053 C CB  . VAL A 1 255 ? 0.507   -42.223 1.055   1   28.74  ? 251 VAL A CB  1 
ATOM   2054 C CG1 . VAL A 1 255 ? 0.463   -40.886 1.785   1   27.71  ? 251 VAL A CG1 1 
ATOM   2055 C CG2 . VAL A 1 255 ? 0.92    -42.038 -0.393  1   27.32  ? 251 VAL A CG2 1 
ATOM   2056 N N   . VAL A 1 256 ? -0.033  -44.012 3.539   1   30.32  ? 252 VAL A N   1 
ATOM   2057 C CA  . VAL A 1 256 ? -0.49   -44.243 4.902   1   29.79  ? 252 VAL A CA  1 
ATOM   2058 C C   . VAL A 1 256 ? -0.843  -45.719 5.025   1   27.36  ? 252 VAL A C   1 
ATOM   2059 O O   . VAL A 1 256 ? -2.016  -46.073 5.039   1   25.46  ? 252 VAL A O   1 
ATOM   2060 C CB  . VAL A 1 256 ? -1.658  -43.337 5.355   1   30.8   ? 252 VAL A CB  1 
ATOM   2061 C CG1 . VAL A 1 256 ? -1.942  -43.477 6.852   1   28.85  ? 252 VAL A CG1 1 
ATOM   2062 C CG2 . VAL A 1 256 ? -1.402  -41.871 4.988   1   28.2   ? 252 VAL A CG2 1 
ATOM   2063 N N   . PRO A 1 257 ? 0.171   -46.608 5.138   1   26.96  ? 253 PRO A N   1 
ATOM   2064 C CA  . PRO A 1 257 ? -0.061  -48.049 5.184   1   26.38  ? 253 PRO A CA  1 
ATOM   2065 C C   . PRO A 1 257 ? -1.192  -48.569 6.063   1   27.86  ? 253 PRO A C   1 
ATOM   2066 O O   . PRO A 1 257 ? -1.925  -49.431 5.605   1   33.16  ? 253 PRO A O   1 
ATOM   2067 C CB  . PRO A 1 257 ? 1.312   -48.607 5.597   1   25.93  ? 253 PRO A CB  1 
ATOM   2068 C CG  . PRO A 1 257 ? 2.291   -47.583 5.057   1   24.27  ? 253 PRO A CG  1 
ATOM   2069 C CD  . PRO A 1 257 ? 1.599   -46.263 5.281   1   24.86  ? 253 PRO A CD  1 
ATOM   2070 N N   . PRO A 1 258 ? -1.396  -48.108 7.324   1   28.61  ? 254 PRO A N   1 
ATOM   2071 C CA  . PRO A 1 258 ? -2.44   -48.68  8.179   1   29.53  ? 254 PRO A CA  1 
ATOM   2072 C C   . PRO A 1 258 ? -3.868  -48.402 7.733   1   31.76  ? 254 PRO A C   1 
ATOM   2073 O O   . PRO A 1 258 ? -4.8    -48.895 8.354   1   39.12  ? 254 PRO A O   1 
ATOM   2074 C CB  . PRO A 1 258 ? -2.217  -48.026 9.528   1   29.26  ? 254 PRO A CB  1 
ATOM   2075 C CG  . PRO A 1 258 ? -0.826  -47.433 9.452   1   28.49  ? 254 PRO A CG  1 
ATOM   2076 C CD  . PRO A 1 258 ? -0.643  -47.053 8.015   1   27.69  ? 254 PRO A CD  1 
ATOM   2077 N N   . LEU A 1 259 ? -4.033  -47.611 6.677   1   28.86  ? 255 LEU A N   1 
ATOM   2078 C CA  . LEU A 1 259 ? -5.323  -47.055 6.32    1   28.04  ? 255 LEU A CA  1 
ATOM   2079 C C   . LEU A 1 259 ? -6.07   -48.041 5.427   1   28.52  ? 255 LEU A C   1 
ATOM   2080 O O   . LEU A 1 259 ? -5.463  -48.685 4.576   1   26.48  ? 255 LEU A O   1 
ATOM   2081 C CB  . LEU A 1 259 ? -5.041  -45.739 5.606   1   26.65  ? 255 LEU A CB  1 
ATOM   2082 C CG  . LEU A 1 259 ? -6.171  -44.715 5.565   1   26.21  ? 255 LEU A CG  1 
ATOM   2083 C CD1 . LEU A 1 259 ? -6.759  -44.496 6.937   1   26.91  ? 255 LEU A CD1 1 
ATOM   2084 C CD2 . LEU A 1 259 ? -5.616  -43.422 4.978   1   27.78  ? 255 LEU A CD2 1 
ATOM   2085 N N   . ASP A 1 260 ? -7.389  -48.155 5.664   1   28.97  ? 256 ASP A N   1 
ATOM   2086 C CA  . ASP A 1 260 ? -8.287  -49.076 4.966   1   31.19  ? 256 ASP A CA  1 
ATOM   2087 C C   . ASP A 1 260 ? -8.627  -48.529 3.574   1   28.18  ? 256 ASP A C   1 
ATOM   2088 O O   . ASP A 1 260 ? -8.234  -47.425 3.201   1   25.5   ? 256 ASP A O   1 
ATOM   2089 C CB  . ASP A 1 260 ? -9.525  -49.352 5.812   1   40.19  ? 256 ASP A CB  1 
ATOM   2090 C CG  . ASP A 1 260 ? -10.129 -48.139 6.53    1   52.32  ? 256 ASP A CG  1 
ATOM   2091 O OD1 . ASP A 1 260 ? -9.513  -47.654 7.533   1   56.01  ? 256 ASP A OD1 1 
ATOM   2092 O OD2 . ASP A 1 260 ? -11.202 -47.659 6.074   1   50.42  ? 256 ASP A OD2 1 
ATOM   2093 N N   . GLU A 1 261 ? -9.374  -49.3   2.785   1   28.75  ? 257 GLU A N   1 
ATOM   2094 C CA  . GLU A 1 261 ? -9.752  -48.85  1.451   1   29.62  ? 257 GLU A CA  1 
ATOM   2095 C C   . GLU A 1 261 ? -10.583 -47.561 1.46    1   29.82  ? 257 GLU A C   1 
ATOM   2096 O O   . GLU A 1 261 ? -10.359 -46.681 0.632   1   28.12  ? 257 GLU A O   1 
ATOM   2097 C CB  . GLU A 1 261 ? -10.58  -49.952 0.811   1   33.33  ? 257 GLU A CB  1 
ATOM   2098 C CG  . GLU A 1 261 ? -10.686 -49.845 -0.707  1   42.57  ? 257 GLU A CG  1 
ATOM   2099 C CD  . GLU A 1 261 ? -11.41  -51.093 -1.213  1   49.44  ? 257 GLU A CD  1 
ATOM   2100 O OE1 . GLU A 1 261 ? -10.738 -52.149 -1.292  1   55.09  ? 257 GLU A OE1 1 
ATOM   2101 O OE2 . GLU A 1 261 ? -12.638 -51.033 -1.449  1   48.65  ? 257 GLU A OE2 1 
ATOM   2102 N N   . ASP A 1 262 ? -11.546 -47.457 2.388   1   28.56  ? 258 ASP A N   1 
ATOM   2103 C CA  . ASP A 1 262 ? -12.406 -46.292 2.53    1   25.65  ? 258 ASP A CA  1 
ATOM   2104 C C   . ASP A 1 262 ? -11.551 -45.094 2.925   1   24.05  ? 258 ASP A C   1 
ATOM   2105 O O   . ASP A 1 262 ? -11.66  -44.001 2.362   1   21.54  ? 258 ASP A O   1 
ATOM   2106 C CB  . ASP A 1 262 ? -13.515 -46.591 3.528   1   29.33  ? 258 ASP A CB  1 
ATOM   2107 C CG  . ASP A 1 262 ? -14.661 -47.468 3.02    1   33.36  ? 258 ASP A CG  1 
ATOM   2108 O OD1 . ASP A 1 262 ? -14.865 -47.514 1.78    1   30.79  ? 258 ASP A OD1 1 
ATOM   2109 O OD2 . ASP A 1 262 ? -15.331 -48.12  3.872   1   32.62  ? 258 ASP A OD2 1 
ATOM   2110 N N   . GLY A 1 263 ? -10.681 -45.317 3.912   1   24.42  ? 259 GLY A N   1 
ATOM   2111 C CA  . GLY A 1 263 ? -9.768  -44.271 4.34    1   25.26  ? 259 GLY A CA  1 
ATOM   2112 C C   . GLY A 1 263 ? -8.921  -43.751 3.177   1   25.05  ? 259 GLY A C   1 
ATOM   2113 O O   . GLY A 1 263 ? -8.921  -42.549 2.921   1   26.19  ? 259 GLY A O   1 
ATOM   2114 N N   . ARG A 1 264 ? -8.264  -44.667 2.447   1   23.93  ? 260 ARG A N   1 
ATOM   2115 C CA  . ARG A 1 264 ? -7.412  -44.314 1.32    1   23.93  ? 260 ARG A CA  1 
ATOM   2116 C C   . ARG A 1 264 ? -8.22   -43.551 0.283   1   22.59  ? 260 ARG A C   1 
ATOM   2117 O O   . ARG A 1 264 ? -7.779  -42.533 -0.229  1   24.06  ? 260 ARG A O   1 
ATOM   2118 C CB  . ARG A 1 264 ? -6.783  -45.544 0.663   1   24.86  ? 260 ARG A CB  1 
ATOM   2119 C CG  . ARG A 1 264 ? -5.698  -46.171 1.534   1   29.24  ? 260 ARG A CG  1 
ATOM   2120 C CD  . ARG A 1 264 ? -4.75   -47.032 0.685   1   29.86  ? 260 ARG A CD  1 
ATOM   2121 N NE  . ARG A 1 264 ? -5.41   -48.114 -0.058  1   27.41  ? 260 ARG A NE  1 
ATOM   2122 C CZ  . ARG A 1 264 ? -5.935  -49.208 0.497   1   26.23  ? 260 ARG A CZ  1 
ATOM   2123 N NH1 . ARG A 1 264 ? -5.729  -49.509 1.779   1   23.8   ? 260 ARG A NH1 1 
ATOM   2124 N NH2 . ARG A 1 264 ? -6.674  -50.003 -0.254  1   25.1   ? 260 ARG A NH2 1 
ATOM   2125 N N   . SER A 1 265 ? -9.423  -44.037 0.007   1   21.8   ? 261 SER A N   1 
ATOM   2126 C CA  . SER A 1 265 ? -10.31  -43.372 -0.932  1   22.44  ? 261 SER A CA  1 
ATOM   2127 C C   . SER A 1 265 ? -10.531 -41.897 -0.557  1   22.21  ? 261 SER A C   1 
ATOM   2128 O O   . SER A 1 265 ? -10.396 -40.995 -1.398  1   22.13  ? 261 SER A O   1 
ATOM   2129 C CB  . SER A 1 265 ? -11.598 -44.154 -1.072  1   21.39  ? 261 SER A CB  1 
ATOM   2130 O OG  . SER A 1 265 ? -12.566 -43.354 -1.725  1   25.76  ? 261 SER A OG  1 
ATOM   2131 N N   . LEU A 1 266 ? -10.87  -41.648 0.711   1   20.69  ? 262 LEU A N   1 
ATOM   2132 C CA  . LEU A 1 266 ? -11.232 -40.298 1.091   1   23.35  ? 262 LEU A CA  1 
ATOM   2133 C C   . LEU A 1 266 ? -9.981  -39.418 1.109   1   26.44  ? 262 LEU A C   1 
ATOM   2134 O O   . LEU A 1 266 ? -10     -38.288 0.603   1   26.75  ? 262 LEU A O   1 
ATOM   2135 C CB  . LEU A 1 266 ? -11.988 -40.33  2.422   1   24.3   ? 262 LEU A CB  1 
ATOM   2136 C CG  . LEU A 1 266 ? -12.1   -39.007 3.186   1   24.46  ? 262 LEU A CG  1 
ATOM   2137 C CD1 . LEU A 1 266 ? -12.869 -37.929 2.42    1   23.98  ? 262 LEU A CD1 1 
ATOM   2138 C CD2 . LEU A 1 266 ? -12.763 -39.29  4.502   1   22.26  ? 262 LEU A CD2 1 
ATOM   2139 N N   . LEU A 1 267 ? -8.886  -39.955 1.66    1   27     ? 263 LEU A N   1 
ATOM   2140 C CA  . LEU A 1 267 ? -7.63   -39.218 1.725   1   28.21  ? 263 LEU A CA  1 
ATOM   2141 C C   . LEU A 1 267 ? -7.168  -38.786 0.327   1   28.9   ? 263 LEU A C   1 
ATOM   2142 O O   . LEU A 1 267 ? -6.802  -37.622 0.129   1   31.46  ? 263 LEU A O   1 
ATOM   2143 C CB  . LEU A 1 267 ? -6.56   -39.999 2.48    1   24.21  ? 263 LEU A CB  1 
ATOM   2144 C CG  . LEU A 1 267 ? -5.216  -39.279 2.559   1   24.14  ? 263 LEU A CG  1 
ATOM   2145 C CD1 . LEU A 1 267 ? -5.348  -37.945 3.314   1   22.62  ? 263 LEU A CD1 1 
ATOM   2146 C CD2 . LEU A 1 267 ? -4.15   -40.165 3.188   1   23.83  ? 263 LEU A CD2 1 
ATOM   2147 N N   . SER A 1 268 ? -7.222  -39.702 -0.648  1   26.07  ? 264 SER A N   1 
ATOM   2148 C CA  . SER A 1 268 ? -6.806  -39.359 -2.003  1   30.92  ? 264 SER A CA  1 
ATOM   2149 C C   . SER A 1 268 ? -7.636  -38.209 -2.57   1   28.72  ? 264 SER A C   1 
ATOM   2150 O O   . SER A 1 268 ? -7.121  -37.395 -3.344  1   33.24  ? 264 SER A O   1 
ATOM   2151 C CB  . SER A 1 268 ? -6.837  -40.537 -2.936  1   31.56  ? 264 SER A CB  1 
ATOM   2152 O OG  . SER A 1 268 ? -8.137  -41.112 -2.898  1   35.21  ? 264 SER A OG  1 
ATOM   2153 N N   . GLN A 1 269 ? -8.903  -38.129 -2.167  1   23.32  ? 265 GLN A N   1 
ATOM   2154 C CA  . GLN A 1 269 ? -9.765  -37.124 -2.752  1   25.33  ? 265 GLN A CA  1 
ATOM   2155 C C   . GLN A 1 269 ? -9.507  -35.771 -2.1    1   26.57  ? 265 GLN A C   1 
ATOM   2156 O O   . GLN A 1 269 ? -9.749  -34.731 -2.713  1   29.23  ? 265 GLN A O   1 
ATOM   2157 C CB  . GLN A 1 269 ? -11.221 -37.563 -2.697  1   24.94  ? 265 GLN A CB  1 
ATOM   2158 C CG  . GLN A 1 269 ? -11.503 -38.746 -3.615  1   28.77  ? 265 GLN A CG  1 
ATOM   2159 C CD  . GLN A 1 269 ? -12.892 -39.292 -3.403  1   30.12  ? 265 GLN A CD  1 
ATOM   2160 O OE1 . GLN A 1 269 ? -13.085 -40.378 -2.835  1   34.14  ? 265 GLN A OE1 1 
ATOM   2161 N NE2 . GLN A 1 269 ? -13.869 -38.467 -3.747  1   28.97  ? 265 GLN A NE2 1 
ATOM   2162 N N   . MET A 1 270 ? -9.023  -35.792 -0.856  1   25.69  ? 266 MET A N   1 
ATOM   2163 C CA  . MET A 1 270 ? -8.67   -34.561 -0.173  1   27.33  ? 266 MET A CA  1 
ATOM   2164 C C   . MET A 1 270 ? -7.332  -34.016 -0.687  1   32.36  ? 266 MET A C   1 
ATOM   2165 O O   . MET A 1 270 ? -7.125  -32.791 -0.685  1   37.39  ? 266 MET A O   1 
ATOM   2166 C CB  . MET A 1 270 ? -8.652  -34.756 1.342   1   25.08  ? 266 MET A CB  1 
ATOM   2167 C CG  . MET A 1 270 ? -9.987  -35.2   1.87    1   25.47  ? 266 MET A CG  1 
ATOM   2168 S SD  . MET A 1 270 ? -10.034 -35.551 3.644   1   26.05  ? 266 MET A SD  1 
ATOM   2169 C CE  . MET A 1 270 ? -9.996  -33.911 4.378   1   18.35  ? 266 MET A CE  1 
ATOM   2170 N N   . LEU A 1 271 ? -6.462  -34.929 -1.155  1   27.45  ? 267 LEU A N   1 
ATOM   2171 C CA  . LEU A 1 271 ? -5.112  -34.592 -1.579  1   25.94  ? 267 LEU A CA  1 
ATOM   2172 C C   . LEU A 1 271 ? -5.001  -34.585 -3.11   1   28.51  ? 267 LEU A C   1 
ATOM   2173 O O   . LEU A 1 271 ? -3.931  -34.772 -3.683  1   27.57  ? 267 LEU A O   1 
ATOM   2174 C CB  . LEU A 1 271 ? -4.143  -35.575 -0.922  1   23.31  ? 267 LEU A CB  1 
ATOM   2175 C CG  . LEU A 1 271 ? -4.062  -35.499 0.611   1   25.69  ? 267 LEU A CG  1 
ATOM   2176 C CD1 . LEU A 1 271 ? -2.945  -36.352 1.188   1   24.99  ? 267 LEU A CD1 1 
ATOM   2177 C CD2 . LEU A 1 271 ? -3.886  -34.073 1.113   1   23.61  ? 267 LEU A CD2 1 
ATOM   2178 N N   . HIS A 1 272 ? -6.11   -34.322 -3.795  1   27.47  ? 268 HIS A N   1 
ATOM   2179 C CA  . HIS A 1 272 ? -6.083  -34.26  -5.245  1   29.16  ? 268 HIS A CA  1 
ATOM   2180 C C   . HIS A 1 272 ? -5.401  -32.963 -5.648  1   28.4   ? 268 HIS A C   1 
ATOM   2181 O O   . HIS A 1 272 ? -5.653  -31.898 -5.06   1   27.02  ? 268 HIS A O   1 
ATOM   2182 C CB  . HIS A 1 272 ? -7.511  -34.37  -5.781  1   33.63  ? 268 HIS A CB  1 
ATOM   2183 C CG  . HIS A 1 272 ? -7.656  -34.884 -7.16   1   40.9   ? 268 HIS A CG  1 
ATOM   2184 N ND1 . HIS A 1 272 ? -7.127  -34.262 -8.275  1   53.23  ? 268 HIS A ND1 1 
ATOM   2185 C CD2 . HIS A 1 272 ? -8.355  -35.945 -7.593  1   43.62  ? 268 HIS A CD2 1 
ATOM   2186 C CE1 . HIS A 1 272 ? -7.48   -34.953 -9.356  1   55.52  ? 268 HIS A CE1 1 
ATOM   2187 N NE2 . HIS A 1 272 ? -8.245  -35.967 -8.961  1   51.01  ? 268 HIS A NE2 1 
ATOM   2188 N N   . TYR A 1 273 ? -4.514  -33.079 -6.644  1   28.51  ? 269 TYR A N   1 
ATOM   2189 C CA  . TYR A 1 273 ? -3.732  -31.932 -7.057  1   27.32  ? 269 TYR A CA  1 
ATOM   2190 C C   . TYR A 1 273 ? -4.66   -30.816 -7.527  1   28.69  ? 269 TYR A C   1 
ATOM   2191 O O   . TYR A 1 273 ? -4.481  -29.661 -7.124  1   31.04  ? 269 TYR A O   1 
ATOM   2192 C CB  . TYR A 1 273 ? -2.704  -32.251 -8.139  1   23.78  ? 269 TYR A CB  1 
ATOM   2193 C CG  . TYR A 1 273 ? -1.378  -32.755 -7.611  1   23.04  ? 269 TYR A CG  1 
ATOM   2194 C CD1 . TYR A 1 273 ? -0.48   -31.892 -7.007  1   23.83  ? 269 TYR A CD1 1 
ATOM   2195 C CD2 . TYR A 1 273 ? -1.047  -34.097 -7.694  1   23.32  ? 269 TYR A CD2 1 
ATOM   2196 C CE1 . TYR A 1 273 ? 0.734   -32.34  -6.512  1   23.82  ? 269 TYR A CE1 1 
ATOM   2197 C CE2 . TYR A 1 273 ? 0.162   -34.555 -7.206  1   26.35  ? 269 TYR A CE2 1 
ATOM   2198 C CZ  . TYR A 1 273 ? 1.07    -33.675 -6.64   1   25.47  ? 269 TYR A CZ  1 
ATOM   2199 O OH  . TYR A 1 273 ? 2.267   -34.142 -6.172  1   25.28  ? 269 TYR A OH  1 
ATOM   2200 N N   . ASP A 1 274 ? -5.589  -31.17  -8.426  1   28.72  ? 270 ASP A N   1 
ATOM   2201 C CA  . ASP A 1 274 ? -6.396  -30.177 -9.111  1   30.33  ? 270 ASP A CA  1 
ATOM   2202 C C   . ASP A 1 274 ? -7.381  -29.662 -8.074  1   31.57  ? 270 ASP A C   1 
ATOM   2203 O O   . ASP A 1 274 ? -8.171  -30.449 -7.569  1   32.72  ? 270 ASP A O   1 
ATOM   2204 C CB  . ASP A 1 274 ? -7.111  -30.779 -10.316 1   29.46  ? 270 ASP A CB  1 
ATOM   2205 C CG  . ASP A 1 274 ? -7.968  -29.823 -11.141 1   30.31  ? 270 ASP A CG  1 
ATOM   2206 O OD1 . ASP A 1 274 ? -8.252  -28.688 -10.659 1   29.74  ? 270 ASP A OD1 1 
ATOM   2207 O OD2 . ASP A 1 274 ? -8.352  -30.217 -12.273 1   30.56  ? 270 ASP A OD2 1 
ATOM   2208 N N   . PRO A 1 275 ? -7.346  -28.365 -7.687  1   31.08  ? 271 PRO A N   1 
ATOM   2209 C CA  . PRO A 1 275 ? -8.259  -27.847 -6.671  1   29.04  ? 271 PRO A CA  1 
ATOM   2210 C C   . PRO A 1 275 ? -9.707  -28.061 -7.107  1   27.72  ? 271 PRO A C   1 
ATOM   2211 O O   . PRO A 1 275 ? -10.587 -28.179 -6.259  1   34.18  ? 271 PRO A O   1 
ATOM   2212 C CB  . PRO A 1 275 ? -7.894  -26.346 -6.535  1   25.64  ? 271 PRO A CB  1 
ATOM   2213 C CG  . PRO A 1 275 ? -6.562  -26.21  -7.154  1   25.9   ? 271 PRO A CG  1 
ATOM   2214 C CD  . PRO A 1 275 ? -6.447  -27.321 -8.199  1   29.58  ? 271 PRO A CD  1 
ATOM   2215 N N   . ASN A 1 276 ? -9.94   -28.093 -8.423  1   27.41  ? 272 ASN A N   1 
ATOM   2216 C CA  . ASN A 1 276 ? -11.278 -28.261 -8.988  1   32.24  ? 272 ASN A CA  1 
ATOM   2217 C C   . ASN A 1 276 ? -11.833 -29.671 -8.751  1   32.44  ? 272 ASN A C   1 
ATOM   2218 O O   . ASN A 1 276 ? -13.049 -29.802 -8.668  1   31.93  ? 272 ASN A O   1 
ATOM   2219 C CB  . ASN A 1 276 ? -11.33  -27.956 -10.488 1   31.83  ? 272 ASN A CB  1 
ATOM   2220 C CG  . ASN A 1 276 ? -11.199 -26.487 -10.819 1   33.85  ? 272 ASN A CG  1 
ATOM   2221 O OD1 . ASN A 1 276 ? -11.523 -25.609 -10.009 1   37.36  ? 272 ASN A OD1 1 
ATOM   2222 N ND2 . ASN A 1 276 ? -10.764 -26.195 -12.03  1   33.69  ? 272 ASN A ND2 1 
ATOM   2223 N N   . LYS A 1 277 ? -10.973 -30.709 -8.674  1   31.37  ? 273 LYS A N   1 
ATOM   2224 C CA  . LYS A 1 277 ? -11.4   -32.09  -8.47   1   30.39  ? 273 LYS A CA  1 
ATOM   2225 C C   . LYS A 1 277 ? -11.357 -32.488 -6.989  1   30.23  ? 273 LYS A C   1 
ATOM   2226 O O   . LYS A 1 277 ? -11.922 -33.502 -6.596  1   33.11  ? 273 LYS A O   1 
ATOM   2227 C CB  . LYS A 1 277 ? -10.528 -33.058 -9.28   1   32.42  ? 273 LYS A CB  1 
ATOM   2228 C CG  . LYS A 1 277 ? -10.506 -32.817 -10.776 1   44.89  ? 273 LYS A CG  1 
ATOM   2229 C CD  . LYS A 1 277 ? -11.875 -33.013 -11.424 1   56.38  ? 273 LYS A CD  1 
ATOM   2230 C CE  . LYS A 1 277 ? -12.208 -32.07  -12.559 1   64.47  ? 273 LYS A CE  1 
ATOM   2231 N NZ  . LYS A 1 277 ? -13.57  -31.516 -12.468 1   57.17  ? 273 LYS A NZ  1 
ATOM   2232 N N   . ARG A 1 278 ? -10.658 -31.711 -6.153  1   28.8   ? 274 ARG A N   1 
ATOM   2233 C CA  . ARG A 1 278 ? -10.494 -32.04  -4.744  1   25.6   ? 274 ARG A CA  1 
ATOM   2234 C C   . ARG A 1 278 ? -11.878 -32.05  -4.096  1   25.35  ? 274 ARG A C   1 
ATOM   2235 O O   . ARG A 1 278 ? -12.719 -31.206 -4.421  1   23.03  ? 274 ARG A O   1 
ATOM   2236 C CB  . ARG A 1 278 ? -9.56   -30.993 -4.126  1   24.39  ? 274 ARG A CB  1 
ATOM   2237 C CG  . ARG A 1 278 ? -8.827  -31.399 -2.856  1   27.59  ? 274 ARG A CG  1 
ATOM   2238 C CD  . ARG A 1 278 ? -7.898  -30.285 -2.349  1   27.38  ? 274 ARG A CD  1 
ATOM   2239 N NE  . ARG A 1 278 ? -6.834  -30.069 -3.336  1   31.38  ? 274 ARG A NE  1 
ATOM   2240 C CZ  . ARG A 1 278 ? -6.132  -28.949 -3.498  1   26.77  ? 274 ARG A CZ  1 
ATOM   2241 N NH1 . ARG A 1 278 ? -6.382  -27.914 -2.74   1   20.29  ? 274 ARG A NH1 1 
ATOM   2242 N NH2 . ARG A 1 278 ? -5.197  -28.875 -4.433  1   26.78  ? 274 ARG A NH2 1 
ATOM   2243 N N   . ILE A 1 279 ? -12.101 -32.991 -3.175  1   22.28  ? 275 ILE A N   1 
ATOM   2244 C CA  . ILE A 1 279 ? -13.423 -33.123 -2.598  1   21.69  ? 275 ILE A CA  1 
ATOM   2245 C C   . ILE A 1 279 ? -13.75  -31.909 -1.738  1   22.47  ? 275 ILE A C   1 
ATOM   2246 O O   . ILE A 1 279 ? -12.867 -31.425 -1.029  1   29.75  ? 275 ILE A O   1 
ATOM   2247 C CB  . ILE A 1 279 ? -13.547 -34.44  -1.816  1   21.75  ? 275 ILE A CB  1 
ATOM   2248 C CG1 . ILE A 1 279 ? -15.015 -34.739 -1.467  1   19.32  ? 275 ILE A CG1 1 
ATOM   2249 C CG2 . ILE A 1 279 ? -12.645 -34.458 -0.587  1   21.49  ? 275 ILE A CG2 1 
ATOM   2250 C CD1 . ILE A 1 279 ? -15.281 -36.183 -1.107  1   17.04  ? 275 ILE A CD1 1 
ATOM   2251 N N   . SER A 1 280 ? -15.006 -31.432 -1.792  1   19.23  ? 276 SER A N   1 
ATOM   2252 C CA  . SER A 1 280 ? -15.502 -30.413 -0.862  1   21.38  ? 276 SER A CA  1 
ATOM   2253 C C   . SER A 1 280 ? -15.842 -31.03  0.499   1   24.4   ? 276 SER A C   1 
ATOM   2254 O O   . SER A 1 280 ? -16.111 -32.226 0.558   1   24.54  ? 276 SER A O   1 
ATOM   2255 C CB  . SER A 1 280 ? -16.739 -29.731 -1.392  1   21.68  ? 276 SER A CB  1 
ATOM   2256 O OG  . SER A 1 280 ? -17.827 -30.637 -1.403  1   15.89  ? 276 SER A OG  1 
ATOM   2257 N N   . ALA A 1 281 ? -15.871 -30.208 1.574   1   26.89  ? 277 ALA A N   1 
ATOM   2258 C CA  . ALA A 1 281 ? -16.229 -30.674 2.914   1   26.5   ? 277 ALA A CA  1 
ATOM   2259 C C   . ALA A 1 281 ? -17.637 -31.27  2.926   1   24.73  ? 277 ALA A C   1 
ATOM   2260 O O   . ALA A 1 281 ? -17.884 -32.325 3.532   1   23.06  ? 277 ALA A O   1 
ATOM   2261 C CB  . ALA A 1 281 ? -16.097 -29.57  3.935   1   26.24  ? 277 ALA A CB  1 
ATOM   2262 N N   . LYS A 1 282 ? -18.544 -30.602 2.212   1   25.28  ? 278 LYS A N   1 
ATOM   2263 C CA  . LYS A 1 282 ? -19.941 -31.009 2.111   1   27.03  ? 278 LYS A CA  1 
ATOM   2264 C C   . LYS A 1 282 ? -20.046 -32.42  1.509   1   27     ? 278 LYS A C   1 
ATOM   2265 O O   . LYS A 1 282 ? -20.634 -33.324 2.087   1   27.07  ? 278 LYS A O   1 
ATOM   2266 C CB  . LYS A 1 282 ? -20.669 -29.852 1.406   1   27.29  ? 278 LYS A CB  1 
ATOM   2267 C CG  . LYS A 1 282 ? -22.063 -30.101 0.885   1   29.64  ? 278 LYS A CG  1 
ATOM   2268 C CD  . LYS A 1 282 ? -22.681 -28.898 0.164   1   33.28  ? 278 LYS A CD  1 
ATOM   2269 C CE  . LYS A 1 282 ? -22.804 -27.645 0.987   1   31.03  ? 278 LYS A CE  1 
ATOM   2270 N NZ  . LYS A 1 282 ? -23.779 -26.698 0.455   1   26.27  ? 278 LYS A NZ  1 
ATOM   2271 N N   . ALA A 1 283 ? -19.422 -32.652 0.359   1   32.07  ? 279 ALA A N   1 
ATOM   2272 C CA  . ALA A 1 283 ? -19.431 -33.976 -0.262  1   30.14  ? 279 ALA A CA  1 
ATOM   2273 C C   . ALA A 1 283 ? -18.745 -35.034 0.612   1   26.19  ? 279 ALA A C   1 
ATOM   2274 O O   . ALA A 1 283 ? -19.22  -36.171 0.689   1   28.36  ? 279 ALA A O   1 
ATOM   2275 C CB  . ALA A 1 283 ? -18.828 -33.928 -1.661  1   26.63  ? 279 ALA A CB  1 
ATOM   2276 N N   . ALA A 1 284 ? -17.625 -34.671 1.249   1   22.51  ? 280 ALA A N   1 
ATOM   2277 C CA  . ALA A 1 284 ? -16.855 -35.613 2.053   1   20.96  ? 280 ALA A CA  1 
ATOM   2278 C C   . ALA A 1 284 ? -17.672 -36.148 3.232   1   21.51  ? 280 ALA A C   1 
ATOM   2279 O O   . ALA A 1 284 ? -17.431 -37.265 3.662   1   21.6   ? 280 ALA A O   1 
ATOM   2280 C CB  . ALA A 1 284 ? -15.567 -34.991 2.5     1   19.61  ? 280 ALA A CB  1 
ATOM   2281 N N   . LEU A 1 285 ? -18.671 -35.401 3.722   1   20.42  ? 281 LEU A N   1 
ATOM   2282 C CA  . LEU A 1 285 ? -19.482 -35.894 4.835   1   20.8   ? 281 LEU A CA  1 
ATOM   2283 C C   . LEU A 1 285 ? -20.214 -37.191 4.481   1   23.64  ? 281 LEU A C   1 
ATOM   2284 O O   . LEU A 1 285 ? -20.574 -37.98  5.364   1   26.73  ? 281 LEU A O   1 
ATOM   2285 C CB  . LEU A 1 285 ? -20.477 -34.833 5.298   1   20.44  ? 281 LEU A CB  1 
ATOM   2286 C CG  . LEU A 1 285 ? -19.899 -33.603 6.001   1   21.76  ? 281 LEU A CG  1 
ATOM   2287 C CD1 . LEU A 1 285 ? -20.978 -32.554 6.184   1   21.26  ? 281 LEU A CD1 1 
ATOM   2288 C CD2 . LEU A 1 285 ? -19.365 -34.011 7.347   1   21.16  ? 281 LEU A CD2 1 
ATOM   2289 N N   . ALA A 1 286 ? -20.485 -37.404 3.187   1   22.28  ? 282 ALA A N   1 
ATOM   2290 C CA  . ALA A 1 286 ? -21.251 -38.564 2.772   1   19.1   ? 282 ALA A CA  1 
ATOM   2291 C C   . ALA A 1 286 ? -20.336 -39.745 2.432   1   19.87  ? 282 ALA A C   1 
ATOM   2292 O O   . ALA A 1 286 ? -20.825 -40.824 2.093   1   19.57  ? 282 ALA A O   1 
ATOM   2293 C CB  . ALA A 1 286 ? -22.104 -38.183 1.6     1   18.56  ? 282 ALA A CB  1 
ATOM   2294 N N   . HIS A 1 287 ? -19.01  -39.573 2.566   1   20.14  ? 283 HIS A N   1 
ATOM   2295 C CA  . HIS A 1 287 ? -18.087 -40.633 2.192   1   22.01  ? 283 HIS A CA  1 
ATOM   2296 C C   . HIS A 1 287 ? -18.32  -41.88  3.043   1   23.14  ? 283 HIS A C   1 
ATOM   2297 O O   . HIS A 1 287 ? -18.593 -41.769 4.235   1   23.12  ? 283 HIS A O   1 
ATOM   2298 C CB  . HIS A 1 287 ? -16.636 -40.161 2.246   1   22.83  ? 283 HIS A CB  1 
ATOM   2299 C CG  . HIS A 1 287 ? -15.683 -41.09  1.583   1   27.17  ? 283 HIS A CG  1 
ATOM   2300 N ND1 . HIS A 1 287 ? -15.284 -42.306 2.115   1   27.8   ? 283 HIS A ND1 1 
ATOM   2301 C CD2 . HIS A 1 287 ? -15.023 -40.956 0.413   1   27.93  ? 283 HIS A CD2 1 
ATOM   2302 C CE1 . HIS A 1 287 ? -14.414 -42.884 1.277   1   28.41  ? 283 HIS A CE1 1 
ATOM   2303 N NE2 . HIS A 1 287 ? -14.226 -42.068 0.249   1   28.25  ? 283 HIS A NE2 1 
ATOM   2304 N N   . PRO A 1 288 ? -18.265 -43.092 2.43    1   24.06  ? 284 PRO A N   1 
ATOM   2305 C CA  . PRO A 1 288 ? -18.404 -44.361 3.148   1   22.78  ? 284 PRO A CA  1 
ATOM   2306 C C   . PRO A 1 288 ? -17.53  -44.499 4.387   1   24.62  ? 284 PRO A C   1 
ATOM   2307 O O   . PRO A 1 288 ? -17.912 -45.216 5.333   1   27.5   ? 284 PRO A O   1 
ATOM   2308 C CB  . PRO A 1 288 ? -18.034 -45.44  2.141   1   22.32  ? 284 PRO A CB  1 
ATOM   2309 C CG  . PRO A 1 288 ? -18.236 -44.785 0.804   1   22.32  ? 284 PRO A CG  1 
ATOM   2310 C CD  . PRO A 1 288 ? -18.054 -43.295 0.984   1   22.86  ? 284 PRO A CD  1 
ATOM   2311 N N   . PHE A 1 289 ? -16.372 -43.825 4.369   1   23.33  ? 285 PHE A N   1 
ATOM   2312 C CA  . PHE A 1 289 ? -15.46  -43.916 5.501   1   26.46  ? 285 PHE A CA  1 
ATOM   2313 C C   . PHE A 1 289 ? -16.208 -43.659 6.82    1   28.1   ? 285 PHE A C   1 
ATOM   2314 O O   . PHE A 1 289 ? -15.869 -44.233 7.862   1   32.85  ? 285 PHE A O   1 
ATOM   2315 C CB  . PHE A 1 289 ? -14.266 -42.983 5.302   1   26.68  ? 285 PHE A CB  1 
ATOM   2316 C CG  . PHE A 1 289 ? -13.251 -42.998 6.433   1   30.74  ? 285 PHE A CG  1 
ATOM   2317 C CD1 . PHE A 1 289 ? -12.373 -44.079 6.579   1   27.96  ? 285 PHE A CD1 1 
ATOM   2318 C CD2 . PHE A 1 289 ? -13.174 -41.932 7.345   1   31.54  ? 285 PHE A CD2 1 
ATOM   2319 C CE1 . PHE A 1 289 ? -11.45  -44.093 7.61    1   26.2   ? 285 PHE A CE1 1 
ATOM   2320 C CE2 . PHE A 1 289 ? -12.237 -41.942 8.376   1   28.59  ? 285 PHE A CE2 1 
ATOM   2321 C CZ  . PHE A 1 289 ? -11.376 -43.026 8.501   1   28.56  ? 285 PHE A CZ  1 
ATOM   2322 N N   . PHE A 1 290 ? -17.252 -42.817 6.768   1   23.57  ? 286 PHE A N   1 
ATOM   2323 C CA  . PHE A 1 290 ? -17.922 -42.364 7.971   1   24.35  ? 286 PHE A CA  1 
ATOM   2324 C C   . PHE A 1 290 ? -19.147 -43.219 8.327   1   28.08  ? 286 PHE A C   1 
ATOM   2325 O O   . PHE A 1 290 ? -19.821 -42.894 9.306   1   29.25  ? 286 PHE A O   1 
ATOM   2326 C CB  . PHE A 1 290 ? -18.304 -40.893 7.773   1   21.98  ? 286 PHE A CB  1 
ATOM   2327 C CG  . PHE A 1 290 ? -17.111 -39.983 7.573   1   20.24  ? 286 PHE A CG  1 
ATOM   2328 C CD1 . PHE A 1 290 ? -16.205 -39.782 8.607   1   19.18  ? 286 PHE A CD1 1 
ATOM   2329 C CD2 . PHE A 1 290 ? -16.92  -39.322 6.365   1   20.41  ? 286 PHE A CD2 1 
ATOM   2330 C CE1 . PHE A 1 290 ? -15.117 -38.967 8.404   1   21.86  ? 286 PHE A CE1 1 
ATOM   2331 C CE2 . PHE A 1 290 ? -15.805 -38.523 6.16    1   22.85  ? 286 PHE A CE2 1 
ATOM   2332 C CZ  . PHE A 1 290 ? -14.905 -38.338 7.186   1   22.95  ? 286 PHE A CZ  1 
ATOM   2333 N N   . GLN A 1 291 ? -19.418 -44.303 7.58    1   29.57  ? 287 GLN A N   1 
ATOM   2334 C CA  . GLN A 1 291 ? -20.65  -45.067 7.724   1   33.24  ? 287 GLN A CA  1 
ATOM   2335 C C   . GLN A 1 291 ? -20.919 -45.464 9.172   1   36.05  ? 287 GLN A C   1 
ATOM   2336 O O   . GLN A 1 291 ? -22.069 -45.534 9.589   1   39.44  ? 287 GLN A O   1 
ATOM   2337 C CB  . GLN A 1 291 ? -20.745 -46.283 6.805   1   34.96  ? 287 GLN A CB  1 
ATOM   2338 C CG  . GLN A 1 291 ? -19.682 -47.348 7.041   1   44.9   ? 287 GLN A CG  1 
ATOM   2339 C CD  . GLN A 1 291 ? -19.745 -48.486 6.039   1   54.71  ? 287 GLN A CD  1 
ATOM   2340 O OE1 . GLN A 1 291 ? -20.633 -49.347 6.113   1   61.02  ? 287 GLN A OE1 1 
ATOM   2341 N NE2 . GLN A 1 291 ? -18.804 -48.518 5.098   1   45.86  ? 287 GLN A NE2 1 
ATOM   2342 N N   . ASP A 1 292 ? -19.863 -45.737 9.94    1   38.11  ? 288 ASP A N   1 
ATOM   2343 C CA  . ASP A 1 292 ? -20.024 -46.379 11.241  1   40.49  ? 288 ASP A CA  1 
ATOM   2344 C C   . ASP A 1 292 ? -19.719 -45.401 12.384  1   39.49  ? 288 ASP A C   1 
ATOM   2345 O O   . ASP A 1 292 ? -19.492 -45.853 13.502  1   39.8   ? 288 ASP A O   1 
ATOM   2346 C CB  . ASP A 1 292 ? -19.22  -47.676 11.307  1   40.45  ? 288 ASP A CB  1 
ATOM   2347 C CG  . ASP A 1 292 ? -17.773 -47.547 10.837  1   51.7   ? 288 ASP A CG  1 
ATOM   2348 O OD1 . ASP A 1 292 ? -17.377 -46.435 10.358  1   52.93  ? 288 ASP A OD1 1 
ATOM   2349 O OD2 . ASP A 1 292 ? -17.04  -48.557 10.924  1   50.02  ? 288 ASP A OD2 1 
ATOM   2350 N N   . VAL A 1 293 ? -19.748 -44.103 12.088  1   40.37  ? 289 VAL A N   1 
ATOM   2351 C CA  . VAL A 1 293 ? -19.589 -43.074 13.155  1   43.14  ? 289 VAL A CA  1 
ATOM   2352 C C   . VAL A 1 293 ? -20.961 -42.964 13.829  1   49.12  ? 289 VAL A C   1 
ATOM   2353 O O   . VAL A 1 293 ? -21.982 -43.034 13.117  1   47.01  ? 289 VAL A O   1 
ATOM   2354 C CB  . VAL A 1 293 ? -19.08  -41.702 12.669  1   43.26  ? 289 VAL A CB  1 
ATOM   2355 C CG1 . VAL A 1 293 ? -20.082 -40.961 11.798  1   43.43  ? 289 VAL A CG1 1 
ATOM   2356 C CG2 . VAL A 1 293 ? -18.63  -40.822 13.828  1   52.04  ? 289 VAL A CG2 1 
ATOM   2357 N N   . THR A 1 294 ? -20.981 -42.866 15.152  1   65.43  ? 290 THR A N   1 
ATOM   2358 C CA  . THR A 1 294 ? -22.267 -42.85  15.867  1   76.5   ? 290 THR A CA  1 
ATOM   2359 C C   . THR A 1 294 ? -22.181 -41.842 16.986  1   84.97  ? 290 THR A C   1 
ATOM   2360 O O   . THR A 1 294 ? -23.23  -41.511 17.561  1   87.5   ? 290 THR A O   1 
ATOM   2361 C CB  . THR A 1 294 ? -22.557 -44.273 16.345  1   77.42  ? 290 THR A CB  1 
ATOM   2362 O OG1 . THR A 1 294 ? -21.446 -44.591 17.177  1   68.94  ? 290 THR A OG1 1 
ATOM   2363 C CG2 . THR A 1 294 ? -22.695 -45.27  15.208  1   77.26  ? 290 THR A CG2 1 
ATOM   2364 N N   . LYS A 1 295 ? -20.975 -41.339 17.259  1   96.37  ? 291 LYS A N   1 
ATOM   2365 C CA  . LYS A 1 295 ? -20.789 -40.31  18.313  1   97.97  ? 291 LYS A CA  1 
ATOM   2366 C C   . LYS A 1 295 ? -21.878 -39.237 18.153  1   94.33  ? 291 LYS A C   1 
ATOM   2367 O O   . LYS A 1 295 ? -21.896 -38.538 17.121  1   94.19  ? 291 LYS A O   1 
ATOM   2368 C CB  . LYS A 1 295 ? -19.38  -39.707 18.274  1   80.9   ? 291 LYS A CB  1 
ATOM   2369 C CG  . LYS A 1 295 ? -19.086 -38.695 19.368  1   74.02  ? 291 LYS A CG  1 
ATOM   2370 C CD  . LYS A 1 295 ? -19.023 -39.307 20.762  1   77.89  ? 291 LYS A CD  1 
ATOM   2371 C CE  . LYS A 1 295 ? -18.732 -38.294 21.82   1   84.62  ? 291 LYS A CE  1 
ATOM   2372 N NZ  . LYS A 1 295 ? -17.396 -37.718 21.655  1   77.77  ? 291 LYS A NZ  1 
ATOM   2373 N N   . PRO A 1 296 ? -22.771 -39.071 19.148  1   95.09  ? 292 PRO A N   1 
ATOM   2374 C CA  . PRO A 1 296 ? -23.836 -38.089 19.053  1   91.66  ? 292 PRO A CA  1 
ATOM   2375 C C   . PRO A 1 296 ? -23.304 -36.711 18.716  1   84.33  ? 292 PRO A C   1 
ATOM   2376 O O   . PRO A 1 296 ? -22.263 -36.29  19.252  1   83.95  ? 292 PRO A O   1 
ATOM   2377 C CB  . PRO A 1 296 ? -24.501 -38.154 20.434  1   84.5   ? 292 PRO A CB  1 
ATOM   2378 C CG  . PRO A 1 296 ? -23.474 -38.829 21.312  1   87.06  ? 292 PRO A CG  1 
ATOM   2379 C CD  . PRO A 1 296 ? -22.77  -39.807 20.396  1   91.75  ? 292 PRO A CD  1 
ATOM   2380 N N   . VAL A 1 297 ? -24.021 -36.007 17.849  1   82.39  ? 293 VAL A N   1 
ATOM   2381 C CA  . VAL A 1 297 ? -23.589 -34.659 17.394  1   80.73  ? 293 VAL A CA  1 
ATOM   2382 C C   . VAL A 1 297 ? -23.404 -33.726 18.596  1   79.51  ? 293 VAL A C   1 
ATOM   2383 O O   . VAL A 1 297 ? -24.293 -33.687 19.473  1   69.55  ? 293 VAL A O   1 
ATOM   2384 C CB  . VAL A 1 297 ? -24.65  -34.132 16.413  1   70.14  ? 293 VAL A CB  1 
ATOM   2385 C CG1 . VAL A 1 297 ? -24.354 -32.701 15.986  1   67.22  ? 293 VAL A CG1 1 
ATOM   2386 C CG2 . VAL A 1 297 ? -24.799 -35.036 15.198  1   65.89  ? 293 VAL A CG2 1 
ATOM   2387 N N   . PRO A 1 298 ? -22.288 -32.973 18.668  1   77.28  ? 294 PRO A N   1 
ATOM   2388 C CA  . PRO A 1 298 ? -22.096 -32.015 19.742  1   73.13  ? 294 PRO A CA  1 
ATOM   2389 C C   . PRO A 1 298 ? -23.197 -30.976 19.701  1   71.59  ? 294 PRO A C   1 
ATOM   2390 O O   . PRO A 1 298 ? -23.776 -30.717 18.633  1   77.38  ? 294 PRO A O   1 
ATOM   2391 C CB  . PRO A 1 298 ? -20.716 -31.428 19.414  1   66.08  ? 294 PRO A CB  1 
ATOM   2392 C CG  . PRO A 1 298 ? -20.051 -32.493 18.58   1   61.86  ? 294 PRO A CG  1 
ATOM   2393 C CD  . PRO A 1 298 ? -21.18  -33.04  17.733  1   66.38  ? 294 PRO A CD  1 
ATOM   2394 N N   . HIS A 1 299 ? -23.491 -30.375 20.849  1   77.38  ? 295 HIS A N   1 
ATOM   2395 C CA  . HIS A 1 299 ? -24.581 -29.4   20.912  1   79.66  ? 295 HIS A CA  1 
ATOM   2396 C C   . HIS A 1 299 ? -24.058 -27.979 20.721  1   76.26  ? 295 HIS A C   1 
ATOM   2397 O O   . HIS A 1 299 ? -22.937 -27.655 21.125  1   76.86  ? 295 HIS A O   1 
ATOM   2398 C CB  . HIS A 1 299 ? -25.377 -29.487 22.223  1   80.38  ? 295 HIS A CB  1 
ATOM   2399 C CG  . HIS A 1 299 ? -26.66  -30.261 22.112  1   101.6  ? 295 HIS A CG  1 
ATOM   2400 N ND1 . HIS A 1 299 ? -27.027 -31.247 23.009  1   103.32 ? 295 HIS A ND1 1 
ATOM   2401 C CD2 . HIS A 1 299 ? -27.659 -30.207 21.202  1   108.12 ? 295 HIS A CD2 1 
ATOM   2402 C CE1 . HIS A 1 299 ? -28.204 -31.754 22.655  1   103.14 ? 295 HIS A CE1 1 
ATOM   2403 N NE2 . HIS A 1 299 ? -28.606 -31.139 21.558  1   106.6  ? 295 HIS A NE2 1 
ATOM   2404 N N   . LEU A 1 300 ? -24.896 -27.12  20.127  1   73.25  ? 296 LEU A N   1 
ATOM   2405 C CA  . LEU A 1 300 ? -24.517 -25.727 19.969  1   79.96  ? 296 LEU A CA  1 
ATOM   2406 C C   . LEU A 1 300 ? -24.326 -25.092 21.348  1   90.84  ? 296 LEU A C   1 
ATOM   2407 O O   . LEU A 1 300 ? -24.743 -25.653 22.363  1   106.62 ? 296 LEU A O   1 
ATOM   2408 C CB  . LEU A 1 300 ? -25.445 -24.9   19.078  1   70.76  ? 296 LEU A CB  1 
ATOM   2409 C CG  . LEU A 1 300 ? -25.134 -24.988 17.578  1   71.33  ? 296 LEU A CG  1 
ATOM   2410 C CD1 . LEU A 1 300 ? -25.379 -26.414 16.992  1   69.61  ? 296 LEU A CD1 1 
ATOM   2411 C CD2 . LEU A 1 300 ? -25.881 -23.914 16.801  1   63.62  ? 296 LEU A CD2 1 
ATOM   2412 N N   . ARG A 1 301 ? -23.664 -23.932 21.36   1   87.26  ? 297 ARG A N   1 
ATOM   2413 C CA  . ARG A 1 301 ? -23.394 -23.205 22.583  1   73.93  ? 297 ARG A CA  1 
ATOM   2414 C C   . ARG A 1 301 ? -24.146 -21.876 22.536  1   67.03  ? 297 ARG A C   1 
ATOM   2415 O O   . ARG A 1 301 ? -24.444 -21.366 21.462  1   60.57  ? 297 ARG A O   1 
ATOM   2416 C CB  . ARG A 1 301 ? -21.879 -23.03  22.674  1   74.11  ? 297 ARG A CB  1 
ATOM   2417 C CG  . ARG A 1 301 ? -21.087 -24.231 23.16   1   67.56  ? 297 ARG A CG  1 
ATOM   2418 C CD  . ARG A 1 301 ? -20.071 -23.601 24.095  1   70.02  ? 297 ARG A CD  1 
ATOM   2419 N NE  . ARG A 1 301 ? -20.534 -23.299 25.456  1   62.28  ? 297 ARG A NE  1 
ATOM   2420 C CZ  . ARG A 1 301 ? -20.335 -24.188 26.418  1   62.3   ? 297 ARG A CZ  1 
ATOM   2421 N NH1 . ARG A 1 301 ? -19.872 -25.378 26.086  1   62.92  ? 297 ARG A NH1 1 
ATOM   2422 N NH2 . ARG A 1 301 ? -20.584 -23.916 27.688  1   57.96  ? 297 ARG A NH2 1 
ATOM   2423 N N   . LEU A 1 302 ? -24.523 -21.354 23.708  1   61.68  ? 298 LEU A N   1 
ATOM   2424 C CA  . LEU A 1 302 ? -25.119 -20.025 23.792  1   59.89  ? 298 LEU A CA  1 
ATOM   2425 C C   . LEU A 1 302 ? -24.166 -19.07  24.534  1   52.42  ? 298 LEU A C   1 
ATOM   2426 O O   . LEU A 1 302 ? -23.127 -19.569 25.011  1   46.26  ? 298 LEU A O   1 
ATOM   2427 C CB  . LEU A 1 302 ? -26.52  -20.098 24.412  1   62.8   ? 298 LEU A CB  1 
ATOM   2428 C CG  . LEU A 1 302 ? -26.626 -20.622 25.851  1   55.69  ? 298 LEU A CG  1 
ATOM   2429 C CD1 . LEU A 1 302 ? -26.276 -19.549 26.847  1   58.4   ? 298 LEU A CD1 1 
ATOM   2430 C CD2 . LEU A 1 302 ? -28.002 -21.187 26.132  1   47.35  ? 298 LEU A CD2 1 
ATOM   2431 N N   . GLY B 2 1   ? -14.997 -23.564 -11.849 1   25.51  ? 171 GLY B N   1 
ATOM   2432 C CA  . GLY B 2 1   ? -14.605 -24.618 -10.895 1   27.66  ? 171 GLY B CA  1 
ATOM   2433 C C   . GLY B 2 1   ? -14.583 -24.081 -9.458  1   29.69  ? 171 GLY B C   1 
ATOM   2434 O O   . GLY B 2 1   ? -15.409 -23.235 -9.084  1   29.61  ? 171 GLY B O   1 
ATOM   2435 N N   . VAL B 2 2   ? -13.594 -24.542 -8.675  1   27.41  ? 172 VAL B N   1 
ATOM   2436 C CA  . VAL B 2 2   ? -13.554 -24.236 -7.254  1   26.83  ? 172 VAL B CA  1 
ATOM   2437 C C   . VAL B 2 2   ? -13.489 -22.719 -6.992  1   27.83  ? 172 VAL B C   1 
ATOM   2438 O O   . VAL B 2 2   ? -13.921 -22.26  -5.929  1   28.25  ? 172 VAL B O   1 
ATOM   2439 C CB  . VAL B 2 2   ? -12.456 -25.035 -6.528  1   25.72  ? 172 VAL B CB  1 
ATOM   2440 C CG1 . VAL B 2 2   ? -11.09  -24.377 -6.705  1   25.15  ? 172 VAL B CG1 1 
ATOM   2441 C CG2 . VAL B 2 2   ? -12.802 -25.266 -5.05   1   22.68  ? 172 VAL B CG2 1 
ATOM   2442 N N   . ASN B 2 3   ? -12.988 -21.923 -7.952  1   26.45  ? 173 ASN B N   1 
ATOM   2443 C CA  . ASN B 2 3   ? -12.891 -20.483 -7.744  1   26.36  ? 173 ASN B CA  1 
ATOM   2444 C C   . ASN B 2 3   ? -14.283 -19.856 -7.696  1   27.19  ? 173 ASN B C   1 
ATOM   2445 O O   . ASN B 2 3   ? -14.43  -18.725 -7.231  1   27.38  ? 173 ASN B O   1 
ATOM   2446 C CB  . ASN B 2 3   ? -11.976 -19.819 -8.767  1   26.63  ? 173 ASN B CB  1 
ATOM   2447 C CG  . ASN B 2 3   ? -10.53  -20.24  -8.605  1   29.35  ? 173 ASN B CG  1 
ATOM   2448 O OD1 . ASN B 2 3   ? -10.104 -20.639 -7.51   1   31.3   ? 173 ASN B OD1 1 
ATOM   2449 N ND2 . ASN B 2 3   ? -9.75   -20.133 -9.671  1   25.63  ? 173 ASN B ND2 1 
ATOM   2450 N N   . GLU B 2 4   ? -15.278 -20.589 -8.219  1   27.21  ? 174 GLU B N   1 
ATOM   2451 C CA  . GLU B 2 4   ? -16.682 -20.217 -8.177  1   30.27  ? 174 GLU B CA  1 
ATOM   2452 C C   . GLU B 2 4   ? -17.447 -21.099 -7.187  1   29.69  ? 174 GLU B C   1 
ATOM   2453 O O   . GLU B 2 4   ? -18.678 -21.129 -7.234  1   29.1   ? 174 GLU B O   1 
ATOM   2454 C CB  . GLU B 2 4   ? -17.309 -20.423 -9.557  1   34.96  ? 174 GLU B CB  1 
ATOM   2455 C CG  . GLU B 2 4   ? -16.317 -20.301 -10.714 1   40.82  ? 174 GLU B CG  1 
ATOM   2456 C CD  . GLU B 2 4   ? -16.976 -20.195 -12.078 1   45.24  ? 174 GLU B CD  1 
ATOM   2457 O OE1 . GLU B 2 4   ? -17.968 -20.906 -12.334 1   44.84  ? 174 GLU B OE1 1 
ATOM   2458 O OE2 . GLU B 2 4   ? -16.472 -19.397 -12.89  1   49.54  ? 174 GLU B OE2 1 
ATOM   2459 N N   . VAL B 2 5   ? -16.714 -21.836 -6.329  1   24.99  ? 175 VAL B N   1 
ATOM   2460 C CA  . VAL B 2 5   ? -17.236 -22.64  -5.23   1   25.18  ? 175 VAL B CA  1 
ATOM   2461 C C   . VAL B 2 5   ? -18.598 -23.232 -5.587  1   25.64  ? 175 VAL B C   1 
ATOM   2462 O O   . VAL B 2 5   ? -19.589 -22.914 -4.934  1   24.9   ? 175 VAL B O   1 
ATOM   2463 C CB  . VAL B 2 5   ? -17.324 -21.907 -3.87   1   24.8   ? 175 VAL B CB  1 
ATOM   2464 C CG1 . VAL B 2 5   ? -15.942 -21.61  -3.312  1   26.78  ? 175 VAL B CG1 1 
ATOM   2465 C CG2 . VAL B 2 5   ? -18.176 -20.639 -3.908  1   20.81  ? 175 VAL B CG2 1 
ATOM   2466 N N   . PRO B 2 6   ? -18.683 -24.102 -6.622  1   28.11  ? 176 PRO B N   1 
ATOM   2467 C CA  . PRO B 2 6   ? -19.948 -24.736 -7.018  1   27.51  ? 176 PRO B CA  1 
ATOM   2468 C C   . PRO B 2 6   ? -20.77  -25.319 -5.86   1   30.05  ? 176 PRO B C   1 
ATOM   2469 O O   . PRO B 2 6   ? -21.997 -25.255 -5.907  1   28.83  ? 176 PRO B O   1 
ATOM   2470 C CB  . PRO B 2 6   ? -19.533 -25.83  -8.032  1   22.81  ? 176 PRO B CB  1 
ATOM   2471 C CG  . PRO B 2 6   ? -18.018 -25.915 -7.929  1   22.2   ? 176 PRO B CG  1 
ATOM   2472 C CD  . PRO B 2 6   ? -17.556 -24.555 -7.455  1   26.19  ? 176 PRO B CD  1 
ATOM   2473 N N   . ASP B 2 7   ? -20.084 -25.87  -4.831  1   29.93  ? 177 ASP B N   1 
ATOM   2474 C CA  . ASP B 2 7   ? -20.717 -26.631 -3.763  1   27.93  ? 177 ASP B CA  1 
ATOM   2475 C C   . ASP B 2 7   ? -21.334 -25.719 -2.696  1   27.5   ? 177 ASP B C   1 
ATOM   2476 O O   . ASP B 2 7   ? -22.077 -26.219 -1.846  1   26.45  ? 177 ASP B O   1 
ATOM   2477 C CB  . ASP B 2 7   ? -19.807 -27.724 -3.214  1   25.49  ? 177 ASP B CB  1 
ATOM   2478 C CG  . ASP B 2 7   ? -19.904 -29.063 -3.927  1   28.98  ? 177 ASP B CG  1 
ATOM   2479 O OD1 . ASP B 2 7   ? -20.449 -29.084 -5.058  1   29.17  ? 177 ASP B OD1 1 
ATOM   2480 O OD2 . ASP B 2 7   ? -19.483 -30.091 -3.335  1   28.43  ? 177 ASP B OD2 1 
ATOM   2481 N N   . TYR B 2 8   ? -21.049 -24.4   -2.763  1   23.33  ? 178 TYR B N   1 
ATOM   2482 C CA  . TYR B 2 8   ? -21.315 -23.469 -1.672  1   21.83  ? 178 TYR B CA  1 
ATOM   2483 C C   . TYR B 2 8   ? -21.976 -22.182 -2.16   1   23.6   ? 178 TYR B C   1 
ATOM   2484 O O   . TYR B 2 8   ? -22.537 -21.46  -1.342  1   26.9   ? 178 TYR B O   1 
ATOM   2485 C CB  . TYR B 2 8   ? -20.067 -23.137 -0.831  1   19.43  ? 178 TYR B CB  1 
ATOM   2486 C CG  . TYR B 2 8   ? -19.424 -24.336 -0.158  1   17.89  ? 178 TYR B CG  1 
ATOM   2487 C CD1 . TYR B 2 8   ? -19.983 -24.888 0.996   1   18.52  ? 178 TYR B CD1 1 
ATOM   2488 C CD2 . TYR B 2 8   ? -18.303 -24.963 -0.702  1   17.64  ? 178 TYR B CD2 1 
ATOM   2489 C CE1 . TYR B 2 8   ? -19.425 -26.001 1.615   1   17.01  ? 178 TYR B CE1 1 
ATOM   2490 C CE2 . TYR B 2 8   ? -17.727 -26.075 -0.092  1   17.4   ? 178 TYR B CE2 1 
ATOM   2491 C CZ  . TYR B 2 8   ? -18.283 -26.588 1.079   1   17.25  ? 178 TYR B CZ  1 
ATOM   2492 O OH  . TYR B 2 8   ? -17.744 -27.695 1.685   1   16.56  ? 178 TYR B OH  1 
ATOM   2493 N N   . HIS B 2 9   ? -21.963 -21.902 -3.468  1   25.7   ? 179 HIS B N   1 
ATOM   2494 C CA  . HIS B 2 9   ? -22.412 -20.596 -3.952  1   31.61  ? 179 HIS B CA  1 
ATOM   2495 C C   . HIS B 2 9   ? -23.872 -20.272 -3.592  1   28.23  ? 179 HIS B C   1 
ATOM   2496 O O   . HIS B 2 9   ? -24.206 -19.101 -3.418  1   26.55  ? 179 HIS B O   1 
ATOM   2497 C CB  . HIS B 2 9   ? -22.08  -20.392 -5.441  1   37.98  ? 179 HIS B CB  1 
ATOM   2498 C CG  . HIS B 2 9   ? -23.082 -20.94  -6.395  1   53.01  ? 179 HIS B CG  1 
ATOM   2499 N ND1 . HIS B 2 9   ? -23.165 -22.278 -6.744  1   56.52  ? 179 HIS B ND1 1 
ATOM   2500 C CD2 . HIS B 2 9   ? -24.057 -20.303 -7.071  1   53.99  ? 179 HIS B CD2 1 
ATOM   2501 C CE1 . HIS B 2 9   ? -24.174 -22.442 -7.594  1   54.37  ? 179 HIS B CE1 1 
ATOM   2502 N NE2 . HIS B 2 9   ? -24.731 -21.259 -7.799  1   59     ? 179 HIS B NE2 1 
ATOM   2503 N N   . GLU B 2 10  ? -24.745 -21.293 -3.541  1   27.31  ? 180 GLU B N   1 
ATOM   2504 C CA  . GLU B 2 10  ? -26.151 -21.094 -3.219  1   27.61  ? 180 GLU B CA  1 
ATOM   2505 C C   . GLU B 2 10  ? -26.284 -20.809 -1.728  1   27.85  ? 180 GLU B C   1 
ATOM   2506 O O   . GLU B 2 10  ? -26.964 -19.847 -1.345  1   29.48  ? 180 GLU B O   1 
ATOM   2507 C CB  . GLU B 2 10  ? -27.051 -22.301 -3.469  1   31.41  ? 180 GLU B CB  1 
ATOM   2508 C CG  . GLU B 2 10  ? -27.415 -22.525 -4.933  1   48.59  ? 180 GLU B CG  1 
ATOM   2509 C CD  . GLU B 2 10  ? -28.221 -23.814 -5.081  1   67.05  ? 180 GLU B CD  1 
ATOM   2510 O OE1 . GLU B 2 10  ? -29.374 -23.905 -4.577  1   62.23  ? 180 GLU B OE1 1 
ATOM   2511 O OE2 . GLU B 2 10  ? -27.662 -24.764 -5.676  1   72.52  ? 180 GLU B OE2 1 
ATOM   2512 N N   . ASP B 2 11  ? -25.666 -21.674 -0.904  1   24.87  ? 181 ASP B N   1 
ATOM   2513 C CA  . ASP B 2 11  ? -25.592 -21.451 0.532   1   24.45  ? 181 ASP B CA  1 
ATOM   2514 C C   . ASP B 2 11  ? -25.148 -20.014 0.778   1   25.56  ? 181 ASP B C   1 
ATOM   2515 O O   . ASP B 2 11  ? -25.781 -19.287 1.537   1   28.3   ? 181 ASP B O   1 
ATOM   2516 C CB  . ASP B 2 11  ? -24.694 -22.448 1.236   1   24.21  ? 181 ASP B CB  1 
ATOM   2517 C CG  . ASP B 2 11  ? -25.216 -23.871 1.376   1   29.74  ? 181 ASP B CG  1 
ATOM   2518 O OD1 . ASP B 2 11  ? -26.45  -24.112 1.161   1   30.02  ? 181 ASP B OD1 1 
ATOM   2519 O OD2 . ASP B 2 11  ? -24.39  -24.737 1.74    1   30.46  ? 181 ASP B OD2 1 
ATOM   2520 N N   . ILE B 2 12  ? -24.085 -19.597 0.082   1   25.21  ? 182 ILE B N   1 
ATOM   2521 C CA  . ILE B 2 12  ? -23.532 -18.277 0.281   1   24.23  ? 182 ILE B CA  1 
ATOM   2522 C C   . ILE B 2 12  ? -24.529 -17.221 -0.177  1   26.29  ? 182 ILE B C   1 
ATOM   2523 O O   . ILE B 2 12  ? -24.738 -16.242 0.533   1   28.4   ? 182 ILE B O   1 
ATOM   2524 C CB  . ILE B 2 12  ? -22.169 -18.157 -0.405  1   22.56  ? 182 ILE B CB  1 
ATOM   2525 C CG1 . ILE B 2 12  ? -21.159 -19.112 0.239   1   21.77  ? 182 ILE B CG1 1 
ATOM   2526 C CG2 . ILE B 2 12  ? -21.664 -16.716 -0.393  1   22.47  ? 182 ILE B CG2 1 
ATOM   2527 C CD1 . ILE B 2 12  ? -19.919 -19.359 -0.61   1   19.66  ? 182 ILE B CD1 1 
ATOM   2528 N N   . HIS B 2 13  ? -25.094 -17.372 -1.382  1   27.2   ? 183 HIS B N   1 
ATOM   2529 C CA  . HIS B 2 13  ? -26.097 -16.42  -1.854  1   25.21  ? 183 HIS B CA  1 
ATOM   2530 C C   . HIS B 2 13  ? -27.226 -16.24  -0.814  1   26.66  ? 183 HIS B C   1 
ATOM   2531 O O   . HIS B 2 13  ? -27.577 -15.118 -0.462  1   26.42  ? 183 HIS B O   1 
ATOM   2532 C CB  . HIS B 2 13  ? -26.664 -16.847 -3.209  1   22.42  ? 183 HIS B CB  1 
ATOM   2533 C CG  . HIS B 2 13  ? -27.748 -15.914 -3.651  1   23.7   ? 183 HIS B CG  1 
ATOM   2534 N ND1 . HIS B 2 13  ? -27.473 -14.67  -4.172  1   23.97  ? 183 HIS B ND1 1 
ATOM   2535 C CD2 . HIS B 2 13  ? -29.074 -15.986 -3.599  1   22.58  ? 183 HIS B CD2 1 
ATOM   2536 C CE1 . HIS B 2 13  ? -28.589 -14.045 -4.471  1   22.4   ? 183 HIS B CE1 1 
ATOM   2537 N NE2 . HIS B 2 13  ? -29.564 -14.826 -4.129  1   24.68  ? 183 HIS B NE2 1 
ATOM   2538 N N   . THR B 2 14  ? -27.805 -17.346 -0.318  1   25.82  ? 184 THR B N   1 
ATOM   2539 C CA  . THR B 2 14  ? -28.868 -17.332 0.681   1   26.57  ? 184 THR B CA  1 
ATOM   2540 C C   . THR B 2 14  ? -28.404 -16.601 1.938   1   30.19  ? 184 THR B C   1 
ATOM   2541 O O   . THR B 2 14  ? -29.135 -15.758 2.451   1   34.14  ? 184 THR B O   1 
ATOM   2542 C CB  . THR B 2 14  ? -29.266 -18.765 1.026   1   27.2   ? 184 THR B CB  1 
ATOM   2543 O OG1 . THR B 2 14  ? -29.906 -19.245 -0.154  1   27.49  ? 184 THR B OG1 1 
ATOM   2544 C CG2 . THR B 2 14  ? -30.217 -18.852 2.209   1   25.09  ? 184 THR B CG2 1 
ATOM   2545 N N   . TYR B 2 15  ? -27.207 -16.938 2.442   1   27.6   ? 185 TYR B N   1 
ATOM   2546 C CA  . TYR B 2 15  ? -26.679 -16.273 3.616   1   25.54  ? 185 TYR B CA  1 
ATOM   2547 C C   . TYR B 2 15  ? -26.552 -14.772 3.387   1   24.21  ? 185 TYR B C   1 
ATOM   2548 O O   . TYR B 2 15  ? -26.977 -14.017 4.25    1   25.81  ? 185 TYR B O   1 
ATOM   2549 C CB  . TYR B 2 15  ? -25.416 -16.968 4.112   1   28.47  ? 185 TYR B CB  1 
ATOM   2550 C CG  . TYR B 2 15  ? -24.716 -16.285 5.278   1   29.98  ? 185 TYR B CG  1 
ATOM   2551 C CD1 . TYR B 2 15  ? -25.268 -16.276 6.558   1   31.79  ? 185 TYR B CD1 1 
ATOM   2552 C CD2 . TYR B 2 15  ? -23.482 -15.686 5.097   1   30.21  ? 185 TYR B CD2 1 
ATOM   2553 C CE1 . TYR B 2 15  ? -24.608 -15.678 7.622   1   30.25  ? 185 TYR B CE1 1 
ATOM   2554 C CE2 . TYR B 2 15  ? -22.796 -15.113 6.15    1   33.49  ? 185 TYR B CE2 1 
ATOM   2555 C CZ  . TYR B 2 15  ? -23.366 -15.104 7.413   1   35.53  ? 185 TYR B CZ  1 
ATOM   2556 O OH  . TYR B 2 15  ? -22.658 -14.508 8.408   1   40.67  ? 185 TYR B OH  1 
ATOM   2557 N N   . LEU B 2 16  ? -26.033 -14.335 2.228   1   24.46  ? 186 LEU B N   1 
ATOM   2558 C CA  . LEU B 2 16  ? -25.843 -12.918 1.966   1   21.98  ? 186 LEU B CA  1 
ATOM   2559 C C   . LEU B 2 16  ? -27.202 -12.218 1.968   1   26.87  ? 186 LEU B C   1 
ATOM   2560 O O   . LEU B 2 16  ? -27.313 -11.081 2.46    1   30.29  ? 186 LEU B O   1 
ATOM   2561 C CB  . LEU B 2 16  ? -25.098 -12.716 0.655   1   21.98  ? 186 LEU B CB  1 
ATOM   2562 C CG  . LEU B 2 16  ? -23.629 -13.165 0.63    1   25.03  ? 186 LEU B CG  1 
ATOM   2563 C CD1 . LEU B 2 16  ? -23.015 -13.066 -0.77   1   21.95  ? 186 LEU B CD1 1 
ATOM   2564 C CD2 . LEU B 2 16  ? -22.761 -12.428 1.656   1   21.77  ? 186 LEU B CD2 1 
ATOM   2565 N N   . ARG B 2 17  ? -28.226 -12.875 1.433   1   24.74  ? 187 ARG B N   1 
ATOM   2566 C CA  . ARG B 2 17  ? -29.577 -12.269 1.37    1   24.44  ? 187 ARG B CA  1 
ATOM   2567 C C   . ARG B 2 17  ? -30.094 -12.022 2.791   1   24.95  ? 187 ARG B C   1 
ATOM   2568 O O   . ARG B 2 17  ? -30.733 -10.988 3.015   1   27.18  ? 187 ARG B O   1 
ATOM   2569 C CB  . ARG B 2 17  ? -30.486 -13.18  0.544   1   21.65  ? 187 ARG B CB  1 
ATOM   2570 C CG  . ARG B 2 17  ? -30.185 -13.205 -0.946  1   22.14  ? 187 ARG B CG  1 
ATOM   2571 C CD  . ARG B 2 17  ? -30.515 -11.888 -1.611  1   24.06  ? 187 ARG B CD  1 
ATOM   2572 N NE  . ARG B 2 17  ? -31.954 -11.609 -1.625  1   22.08  ? 187 ARG B NE  1 
ATOM   2573 C CZ  . ARG B 2 17  ? -32.84  -12.229 -2.387  1   22.68  ? 187 ARG B CZ  1 
ATOM   2574 N NH1 . ARG B 2 17  ? -32.483 -12.706 -3.562  1   25.4   ? 187 ARG B NH1 1 
ATOM   2575 N NH2 . ARG B 2 17  ? -34.084 -12.358 -1.973  1   19.69  ? 187 ARG B NH2 1 
ATOM   2576 N N   . GLU B 2 18  ? -29.819 -12.939 3.71    1   25.83  ? 188 GLU B N   1 
ATOM   2577 C CA  . GLU B 2 18  ? -30.203 -12.774 5.098   1   31.17  ? 188 GLU B CA  1 
ATOM   2578 C C   . GLU B 2 18  ? -29.351 -11.667 5.737   1   31.74  ? 188 GLU B C   1 
ATOM   2579 O O   . GLU B 2 18  ? -29.878 -10.811 6.428   1   36.1   ? 188 GLU B O   1 
ATOM   2580 C CB  . GLU B 2 18  ? -30.216 -14.159 5.764   1   32.75  ? 188 GLU B CB  1 
ATOM   2581 C CG  . GLU B 2 18  ? -30.32  -14.083 7.284   1   40     ? 188 GLU B CG  1 
ATOM   2582 C CD  . GLU B 2 18  ? -30.037 -15.319 8.118   1   46.8   ? 188 GLU B CD  1 
ATOM   2583 O OE1 . GLU B 2 18  ? -29.598 -16.378 7.592   1   48.68  ? 188 GLU B OE1 1 
ATOM   2584 O OE2 . GLU B 2 18  ? -30.287 -15.178 9.336   1   43.38  ? 188 GLU B OE2 1 
ATOM   2585 N N   . MET B 2 19  ? -28.058 -11.637 5.461   1   27.71  ? 189 MET B N   1 
ATOM   2586 C CA  . MET B 2 19  ? -27.182 -10.663 6.16    1   29.97  ? 189 MET B CA  1 
ATOM   2587 C C   . MET B 2 19  ? -27.393 -9.239  5.631   1   34.85  ? 189 MET B C   1 
ATOM   2588 O O   . MET B 2 19  ? -27.106 -8.299  6.379   1   36.13  ? 189 MET B O   1 
ATOM   2589 C CB  . MET B 2 19  ? -25.717 -11.08  6.022   1   29.38  ? 189 MET B CB  1 
ATOM   2590 C CG  . MET B 2 19  ? -25.373 -12.35  6.755   1   35.5   ? 189 MET B CG  1 
ATOM   2591 S SD  . MET B 2 19  ? -25.918 -12.341 8.473   1   43.45  ? 189 MET B SD  1 
ATOM   2592 C CE  . MET B 2 19  ? -24.822 -11.065 9.102   1   44.81  ? 189 MET B CE  1 
ATOM   2593 N N   . GLU B 2 20  ? -27.896 -9.092  4.41    1   29.11  ? 190 GLU B N   1 
ATOM   2594 C CA  . GLU B 2 20  ? -28.055 -7.749  3.8     1   25.23  ? 190 GLU B CA  1 
ATOM   2595 C C   . GLU B 2 20  ? -29.181 -6.989  4.508   1   26.82  ? 190 GLU B C   1 
ATOM   2596 O O   . GLU B 2 20  ? -29.101 -5.759  4.563   1   31.51  ? 190 GLU B O   1 
ATOM   2597 C CB  . GLU B 2 20  ? -28.235 -7.906  2.291   1   24.55  ? 190 GLU B CB  1 
ATOM   2598 C CG  . GLU B 2 20  ? -29.674 -7.984  1.8     1   25.4   ? 190 GLU B CG  1 
ATOM   2599 C CD  . GLU B 2 20  ? -29.679 -8.018  0.287   1   27.81  ? 190 GLU B CD  1 
ATOM   2600 O OE1 . GLU B 2 20  ? -28.82  -7.352  -0.313  1   27.46  ? 190 GLU B OE1 1 
ATOM   2601 O OE2 . GLU B 2 20  ? -30.531 -8.711  -0.289  1   29.44  ? 190 GLU B OE2 1 
ATOM   2602 N N   . VAL B 2 21  ? -30.162 -7.703  5.047   1   24.78  ? 191 VAL B N   1 
ATOM   2603 C CA  . VAL B 2 21  ? -31.287 -7.064  5.785   1   26.35  ? 191 VAL B CA  1 
ATOM   2604 C C   . VAL B 2 21  ? -30.782 -6.649  7.17    1   28.22  ? 191 VAL B C   1 
ATOM   2605 O O   . VAL B 2 21  ? -31.154 -5.566  7.635   1   33.41  ? 191 VAL B O   1 
ATOM   2606 C CB  . VAL B 2 21  ? -32.483 -8.029  5.87    1   25.23  ? 191 VAL B CB  1 
ATOM   2607 C CG1 . VAL B 2 21  ? -33.66  -7.416  6.612   1   19.44  ? 191 VAL B CG1 1 
ATOM   2608 C CG2 . VAL B 2 21  ? -32.91  -8.514  4.492   1   21.39  ? 191 VAL B CG2 1 
ATOM   2609 N N   . LYS B 2 22  ? -29.942 -7.474  7.775   1   30.81  ? 192 LYS B N   1 
ATOM   2610 C CA  . LYS B 2 22  ? -29.394 -7.168  9.112   1   34.59  ? 192 LYS B CA  1 
ATOM   2611 C C   . LYS B 2 22  ? -28.446 -5.974  9.012   1   38.34  ? 192 LYS B C   1 
ATOM   2612 O O   . LYS B 2 22  ? -28.466 -5.124  9.913   1   39.41  ? 192 LYS B O   1 
ATOM   2613 C CB  . LYS B 2 22  ? -28.676 -8.431  9.586   1   40.57  ? 192 LYS B CB  1 
ATOM   2614 C CG  . LYS B 2 22  ? -27.392 -8.237  10.372  1   53.12  ? 192 LYS B CG  1 
ATOM   2615 C CD  . LYS B 2 22  ? -27.205 -9.306  11.439  1   66.97  ? 192 LYS B CD  1 
ATOM   2616 C CE  . LYS B 2 22  ? -25.873 -9.232  12.109  1   80.2   ? 192 LYS B CE  1 
ATOM   2617 N NZ  . LYS B 2 22  ? -25.489 -10.532 12.664  1   80.72  ? 192 LYS B NZ  1 
ATOM   2618 N N   . CYS B 2 23  ? -27.681 -5.899  7.931   1   38.21  ? 193 CYS B N   1 
ATOM   2619 C CA  . CYS B 2 23  ? -26.653 -4.838  7.805   1   42.62  ? 193 CYS B CA  1 
ATOM   2620 C C   . CYS B 2 23  ? -27.235 -3.645  7.033   1   41.97  ? 193 CYS B C   1 
ATOM   2621 O O   . CYS B 2 23  ? -26.446 -2.835  6.529   1   45.5   ? 193 CYS B O   1 
ATOM   2622 C CB  . CYS B 2 23  ? -25.406 -5.381  7.112   1   42.98  ? 193 CYS B CB  1 
ATOM   2623 S SG  . CYS B 2 23  ? -24.477 -6.61   8.064   1   51.29  ? 193 CYS B SG  1 
ATOM   2624 N N   . LYS B 2 24  ? -28.561 -3.539  6.956   1   33.93  ? 194 LYS B N   1 
ATOM   2625 C CA  . LYS B 2 24  ? -29.139 -2.456  6.179   1   33.81  ? 194 LYS B CA  1 
ATOM   2626 C C   . LYS B 2 24  ? -29.209 -1.203  7.05    1   36.84  ? 194 LYS B C   1 
ATOM   2627 O O   . LYS B 2 24  ? -29.589 -1.283  8.221   1   37.01  ? 194 LYS B O   1 
ATOM   2628 C CB  . LYS B 2 24  ? -30.534 -2.831  5.67    1   36.12  ? 194 LYS B CB  1 
ATOM   2629 C CG  . LYS B 2 24  ? -31.146 -1.849  4.692   1   39.57  ? 194 LYS B CG  1 
ATOM   2630 C CD  . LYS B 2 24  ? -32.626 -2.042  4.395   1   41.31  ? 194 LYS B CD  1 
ATOM   2631 C CE  . LYS B 2 24  ? -33.031 -1.333  3.12    1   45     ? 194 LYS B CE  1 
ATOM   2632 N NZ  . LYS B 2 24  ? -34.405 -1.66   2.707   1   51.37  ? 194 LYS B NZ  1 
ATOM   2633 N N   . PRO B 2 25  ? -28.844 -0.015  6.501   1   38.38  ? 195 PRO B N   1 
ATOM   2634 C CA  . PRO B 2 25  ? -29.002 1.263   7.199   1   34.1   ? 195 PRO B CA  1 
ATOM   2635 C C   . PRO B 2 25  ? -30.462 1.653   7.284   1   34.09  ? 195 PRO B C   1 
ATOM   2636 O O   . PRO B 2 25  ? -31.255 1.179   6.49    1   41.78  ? 195 PRO B O   1 
ATOM   2637 C CB  . PRO B 2 25  ? -28.261 2.29    6.326   1   36.61  ? 195 PRO B CB  1 
ATOM   2638 C CG  . PRO B 2 25  ? -27.456 1.479   5.304   1   35.39  ? 195 PRO B CG  1 
ATOM   2639 C CD  . PRO B 2 25  ? -28.186 0.151   5.191   1   38.36  ? 195 PRO B CD  1 
ATOM   2640 N N   . LYS B 2 26  ? -30.766 2.616   8.15    1   31.92  ? 196 LYS B N   1 
ATOM   2641 C CA  . LYS B 2 26  ? -32.137 3.164   8.242   1   35.66  ? 196 LYS B CA  1 
ATOM   2642 C C   . LYS B 2 26  ? -32.38  4.071   7.034   1   37.11  ? 196 LYS B C   1 
ATOM   2643 O O   . LYS B 2 26  ? -31.603 5.012   6.835   1   38.57  ? 196 LYS B O   1 
ATOM   2644 C CB  . LYS B 2 26  ? -32.283 3.978   9.528   1   37.47  ? 196 LYS B CB  1 
ATOM   2645 C CG  . LYS B 2 26  ? -33.681 4.512   9.783   1   47.38  ? 196 LYS B CG  1 
ATOM   2646 C CD  . LYS B 2 26  ? -33.719 5.84    10.528  1   55.77  ? 196 LYS B CD  1 
ATOM   2647 C CE  . LYS B 2 26  ? -32.667 5.943   11.58   1   61.25  ? 196 LYS B CE  1 
ATOM   2648 N NZ  . LYS B 2 26  ? -32.39  7.339   11.922  1   72.76  ? 196 LYS B NZ  1 
ATOM   2649 N N   . VAL B 2 27  ? -33.438 3.802   6.272   1   35.17  ? 197 VAL B N   1 
ATOM   2650 C CA  . VAL B 2 27  ? -33.699 4.56    5.015   1   35.73  ? 197 VAL B CA  1 
ATOM   2651 C C   . VAL B 2 27  ? -33.845 6.061   5.307   1   37.37  ? 197 VAL B C   1 
ATOM   2652 O O   . VAL B 2 27  ? -33.423 6.867   4.466   1   35.95  ? 197 VAL B O   1 
ATOM   2653 C CB  . VAL B 2 27  ? -34.938 3.982   4.307   1   38.54  ? 197 VAL B CB  1 
ATOM   2654 C CG1 . VAL B 2 27  ? -35.195 4.645   2.962   1   33.77  ? 197 VAL B CG1 1 
ATOM   2655 C CG2 . VAL B 2 27  ? -34.828 2.473   4.14    1   43     ? 197 VAL B CG2 1 
ATOM   2656 N N   . GLY B 2 28  ? -34.397 6.428   6.457   1   38.44  ? 198 GLY B N   1 
ATOM   2657 C CA  . GLY B 2 28  ? -34.633 7.861   6.709   1   49.26  ? 198 GLY B CA  1 
ATOM   2658 C C   . GLY B 2 28  ? -33.804 8.415   7.843   1   52.63  ? 198 GLY B C   1 
ATOM   2659 O O   . GLY B 2 28  ? -34.405 8.925   8.804   1   55.97  ? 198 GLY B O   1 
ATOM   2660 N N   . TYR B 2 29  ? -32.479 8.363   7.727   1   46.23  ? 199 TYR B N   1 
ATOM   2661 C CA  . TYR B 2 29  ? -31.618 8.801   8.856   1   35.86  ? 199 TYR B CA  1 
ATOM   2662 C C   . TYR B 2 29  ? -31.197 10.231  8.634   1   33.73  ? 199 TYR B C   1 
ATOM   2663 O O   . TYR B 2 29  ? -30.979 10.939  9.623   1   32.27  ? 199 TYR B O   1 
ATOM   2664 C CB  . TYR B 2 29  ? -30.437 7.835   9.033   1   34.18  ? 199 TYR B CB  1 
ATOM   2665 C CG  . TYR B 2 29  ? -29.241 7.898   8.092   1   26.61  ? 199 TYR B CG  1 
ATOM   2666 C CD1 . TYR B 2 29  ? -28.388 8.992   8.07    1   26.8   ? 199 TYR B CD1 1 
ATOM   2667 C CD2 . TYR B 2 29  ? -28.932 6.826   7.268   1   27.98  ? 199 TYR B CD2 1 
ATOM   2668 C CE1 . TYR B 2 29  ? -27.3   9.044   7.219   1   26.58  ? 199 TYR B CE1 1 
ATOM   2669 C CE2 . TYR B 2 29  ? -27.839 6.858   6.421   1   28.64  ? 199 TYR B CE2 1 
ATOM   2670 C CZ  . TYR B 2 29  ? -27.02  7.97    6.398   1   28.52  ? 199 TYR B CZ  1 
ATOM   2671 O OH  . TYR B 2 29  ? -25.941 8.011   5.57    1   30.56  ? 199 TYR B OH  1 
ATOM   2672 N N   . MET B 2 30  ? -31.099 10.645  7.375   1   33.06  ? 200 MET B N   1 
ATOM   2673 C CA  . MET B 2 30  ? -30.557 11.994  7.096   1   33.89  ? 200 MET B CA  1 
ATOM   2674 C C   . MET B 2 30  ? -31.539 13.058  7.585   1   37.47  ? 200 MET B C   1 
ATOM   2675 O O   . MET B 2 30  ? -31.078 14.124  8.012   1   40.43  ? 200 MET B O   1 
ATOM   2676 C CB  . MET B 2 30  ? -30.281 12.172  5.604   1   35.1   ? 200 MET B CB  1 
ATOM   2677 C CG  . MET B 2 30  ? -29.207 13.185  5.299   1   35.98  ? 200 MET B CG  1 
ATOM   2678 S SD  . MET B 2 30  ? -27.701 12.868  6.235   1   35.92  ? 200 MET B SD  1 
ATOM   2679 C CE  . MET B 2 30  ? -26.779 11.906  5.032   1   41.03  ? 200 MET B CE  1 
ATOM   2680 N N   . LYS B 2 31  ? -32.835 12.766  7.531   1   39.37  ? 201 LYS B N   1 
ATOM   2681 C CA  . LYS B 2 31  ? -33.82  13.738  8.061   1   38.76  ? 201 LYS B CA  1 
ATOM   2682 C C   . LYS B 2 31  ? -33.605 13.896  9.569   1   36.26  ? 201 LYS B C   1 
ATOM   2683 O O   . LYS B 2 31  ? -33.866 14.99   10.085  1   37.75  ? 201 LYS B O   1 
ATOM   2684 C CB  . LYS B 2 31  ? -35.251 13.299  7.737   1   41.78  ? 201 LYS B CB  1 
ATOM   2685 C CG  . LYS B 2 31  ? -35.629 13.315  6.269   1   47.3   ? 201 LYS B CG  1 
ATOM   2686 C CD  . LYS B 2 31  ? -37.058 12.841  6.042   1   56.4   ? 201 LYS B CD  1 
ATOM   2687 C CE  . LYS B 2 31  ? -37.443 12.878  4.599   1   59.47  ? 201 LYS B CE  1 
ATOM   2688 N NZ  . LYS B 2 31  ? -38.811 12.395  4.406   1   59.33  ? 201 LYS B NZ  1 
ATOM   2689 N N   . LYS B 2 32  ? -33.118 12.851  10.23   1   38.26  ? 202 LYS B N   1 
ATOM   2690 C CA  . LYS B 2 32  ? -32.917 12.893  11.699  1   36.55  ? 202 LYS B CA  1 
ATOM   2691 C C   . LYS B 2 32  ? -31.498 13.375  11.992  1   36.54  ? 202 LYS B C   1 
ATOM   2692 O O   . LYS B 2 32  ? -31.144 13.455  13.175  1   39.98  ? 202 LYS B O   1 
ATOM   2693 C CB  . LYS B 2 32  ? -33.163 11.518  12.319  1   38.96  ? 202 LYS B CB  1 
ATOM   2694 C CG  . LYS B 2 32  ? -34.599 11.03   12.254  1   51.35  ? 202 LYS B CG  1 
ATOM   2695 C CD  . LYS B 2 32  ? -34.797 9.646   12.861  1   59.71  ? 202 LYS B CD  1 
ATOM   2696 C CE  . LYS B 2 32  ? -36.216 9.182   12.815  1   66.06  ? 202 LYS B CE  1 
ATOM   2697 N NZ  . LYS B 2 32  ? -36.376 7.841   13.382  1   65.08  ? 202 LYS B NZ  1 
ATOM   2698 N N   . GLN B 2 33  ? -30.722 13.66   10.95   1   32.45  ? 203 GLN B N   1 
ATOM   2699 C CA  . GLN B 2 33  ? -29.366 14.227  11.154  1   28.51  ? 203 GLN B CA  1 
ATOM   2700 C C   . GLN B 2 33  ? -29.518 15.75   11.099  1   26.24  ? 203 GLN B C   1 
ATOM   2701 O O   . GLN B 2 33  ? -29.797 16.286  10.019  1   27.06  ? 203 GLN B O   1 
ATOM   2702 C CB  . GLN B 2 33  ? -28.363 13.629  10.166  1   25.23  ? 203 GLN B CB  1 
ATOM   2703 C CG  . GLN B 2 33  ? -27.966 12.19   10.473  1   24.5   ? 203 GLN B CG  1 
ATOM   2704 C CD  . GLN B 2 33  ? -26.792 12.066  11.417  1   25.82  ? 203 GLN B CD  1 
ATOM   2705 O OE1 . GLN B 2 33  ? -26.201 13.055  11.858  1   24.4   ? 203 GLN B OE1 1 
ATOM   2706 N NE2 . GLN B 2 33  ? -26.439 10.832  11.736  1   25.87  ? 203 GLN B NE2 1 
ATOM   2707 N N   . PRO B 2 34  ? -29.36  16.459  12.23   1   27.04  ? 204 PRO B N   1 
ATOM   2708 C CA  . PRO B 2 34  ? -29.622 17.899  12.265  1   28.12  ? 204 PRO B CA  1 
ATOM   2709 C C   . PRO B 2 34  ? -28.674 18.748  11.422  1   29.24  ? 204 PRO B C   1 
ATOM   2710 O O   . PRO B 2 34  ? -29.052 19.841  11.008  1   33.23  ? 204 PRO B O   1 
ATOM   2711 C CB  . PRO B 2 34  ? -29.564 18.25   13.764  1   25.19  ? 204 PRO B CB  1 
ATOM   2712 C CG  . PRO B 2 34  ? -28.704 17.15   14.367  1   25.59  ? 204 PRO B CG  1 
ATOM   2713 C CD  . PRO B 2 34  ? -28.978 15.904  13.545  1   25.71  ? 204 PRO B CD  1 
ATOM   2714 N N   . ASP B 2 35  ? -27.46  18.24   11.16   1   29.15  ? 205 ASP B N   1 
ATOM   2715 C CA  . ASP B 2 35  ? -26.404 19.104  10.664  1   29.74  ? 205 ASP B CA  1 
ATOM   2716 C C   . ASP B 2 35  ? -25.787 18.616  9.356   1   31.64  ? 205 ASP B C   1 
ATOM   2717 O O   . ASP B 2 35  ? -24.942 19.314  8.788   1   32.64  ? 205 ASP B O   1 
ATOM   2718 C CB  . ASP B 2 35  ? -25.331 19.347  11.705  1   29.06  ? 205 ASP B CB  1 
ATOM   2719 C CG  . ASP B 2 35  ? -24.536 20.597  11.391  1   32.67  ? 205 ASP B CG  1 
ATOM   2720 O OD1 . ASP B 2 35  ? -25.173 21.691  11.348  1   31.96  ? 205 ASP B OD1 1 
ATOM   2721 O OD2 . ASP B 2 35  ? -23.32  20.448  11.11   1   31.93  ? 205 ASP B OD2 1 
ATOM   2722 N N   . ILE B 2 36  ? -26.2   17.427  8.896   1   31.13  ? 206 ILE B N   1 
ATOM   2723 C CA  . ILE B 2 36  ? -25.717 16.881  7.64    1   31.92  ? 206 ILE B CA  1 
ATOM   2724 C C   . ILE B 2 36  ? -26.882 16.524  6.721   1   34.84  ? 206 ILE B C   1 
ATOM   2725 O O   . ILE B 2 36  ? -28.028 16.345  7.164   1   36.49  ? 206 ILE B O   1 
ATOM   2726 C CB  . ILE B 2 36  ? -24.734 15.714  7.839   1   32.52  ? 206 ILE B CB  1 
ATOM   2727 C CG1 . ILE B 2 36  ? -25.361 14.529  8.538   1   31.18  ? 206 ILE B CG1 1 
ATOM   2728 C CG2 . ILE B 2 36  ? -23.461 16.188  8.538   1   33.67  ? 206 ILE B CG2 1 
ATOM   2729 C CD1 . ILE B 2 36  ? -24.392 13.378  8.77    1   33.53  ? 206 ILE B CD1 1 
ATOM   2730 N N   . THR B 2 37  ? -26.544 16.464  5.419   1   33.37  ? 207 THR B N   1 
ATOM   2731 C CA  . THR B 2 37  ? -27.483 16.355  4.31    1   30.91  ? 207 THR B CA  1 
ATOM   2732 C C   . THR B 2 37  ? -26.969 15.308  3.34    1   32.45  ? 207 THR B C   1 
ATOM   2733 O O   . THR B 2 37  ? -25.782 14.951  3.373   1   34.92  ? 207 THR B O   1 
ATOM   2734 C CB  . THR B 2 37  ? -27.589 17.669  3.537   1   28.05  ? 207 THR B CB  1 
ATOM   2735 O OG1 . THR B 2 37  ? -26.279 17.954  3.045   1   28.64  ? 207 THR B OG1 1 
ATOM   2736 C CG2 . THR B 2 37  ? -28.154 18.811  4.356   1   23.19  ? 207 THR B CG2 1 
ATOM   2737 N N   . ASN B 2 38  ? -27.875 14.888  2.451   1   30.88  ? 208 ASN B N   1 
ATOM   2738 C CA  . ASN B 2 38  ? -27.548 13.951  1.392   1   30.53  ? 208 ASN B CA  1 
ATOM   2739 C C   . ASN B 2 38  ? -26.364 14.479  0.574   1   28.63  ? 208 ASN B C   1 
ATOM   2740 O O   . ASN B 2 38  ? -25.478 13.734  0.155   1   27.18  ? 208 ASN B O   1 
ATOM   2741 C CB  . ASN B 2 38  ? -28.777 13.634  0.551   1   30.95  ? 208 ASN B CB  1 
ATOM   2742 C CG  . ASN B 2 38  ? -29.77  12.769  1.293   1   34.69  ? 208 ASN B CG  1 
ATOM   2743 O OD1 . ASN B 2 38  ? -29.385 11.969  2.16    1   39.94  ? 208 ASN B OD1 1 
ATOM   2744 N ND2 . ASN B 2 38  ? -31.041 12.881  0.94    1   30.57  ? 208 ASN B ND2 1 
ATOM   2745 N N   . SER B 2 39  ? -26.344 15.792  0.399   1   27.01  ? 209 SER B N   1 
ATOM   2746 C CA  . SER B 2 39  ? -25.371 16.417  -0.469  1   30.3   ? 209 SER B CA  1 
ATOM   2747 C C   . SER B 2 39  ? -23.971 16.312  0.145   1   33.08  ? 209 SER B C   1 
ATOM   2748 O O   . SER B 2 39  ? -22.994 16.068  -0.563  1   33.83  ? 209 SER B O   1 
ATOM   2749 C CB  . SER B 2 39  ? -25.808 17.824  -0.763  1   30.3   ? 209 SER B CB  1 
ATOM   2750 O OG  . SER B 2 39  ? -24.682 18.641  -1.025  1   38.12  ? 209 SER B OG  1 
ATOM   2751 N N   . MET B 2 40  ? -23.878 16.475  1.471   1   32.56  ? 210 MET B N   1 
ATOM   2752 C CA  . MET B 2 40  ? -22.61  16.338  2.173   1   32.13  ? 210 MET B CA  1 
ATOM   2753 C C   . MET B 2 40  ? -22.102 14.903  2.114   1   31.64  ? 210 MET B C   1 
ATOM   2754 O O   . MET B 2 40  ? -20.904 14.668  1.928   1   32.81  ? 210 MET B O   1 
ATOM   2755 C CB  . MET B 2 40  ? -22.771 16.743  3.637   1   30.74  ? 210 MET B CB  1 
ATOM   2756 C CG  . MET B 2 40  ? -22.917 18.224  3.772   1   32.83  ? 210 MET B CG  1 
ATOM   2757 S SD  . MET B 2 40  ? -23.228 18.651  5.491   1   36.7   ? 210 MET B SD  1 
ATOM   2758 C CE  . MET B 2 40  ? -23.897 20.309  5.296   1   30.48  ? 210 MET B CE  1 
ATOM   2759 N N   . ARG B 2 41  ? -23.029 13.961  2.303   1   31.04  ? 211 ARG B N   1 
ATOM   2760 C CA  . ARG B 2 41  ? -22.733 12.536  2.262   1   31.23  ? 211 ARG B CA  1 
ATOM   2761 C C   . ARG B 2 41  ? -22.15  12.207  0.895   1   30.39  ? 211 ARG B C   1 
ATOM   2762 O O   . ARG B 2 41  ? -21.246 11.386  0.773   1   32.78  ? 211 ARG B O   1 
ATOM   2763 C CB  . ARG B 2 41  ? -24.017 11.724  2.493   1   31.99  ? 211 ARG B CB  1 
ATOM   2764 C CG  . ARG B 2 41  ? -23.78  10.236  2.714   1   32.6   ? 211 ARG B CG  1 
ATOM   2765 C CD  . ARG B 2 41  ? -25.081 9.458   2.557   1   32.99  ? 211 ARG B CD  1 
ATOM   2766 N NE  . ARG B 2 41  ? -24.875 8.035   2.263   1   31.67  ? 211 ARG B NE  1 
ATOM   2767 C CZ  . ARG B 2 41  ? -24.555 7.531   1.075   1   30.71  ? 211 ARG B CZ  1 
ATOM   2768 N NH1 . ARG B 2 41  ? -24.541 8.322   0.025   1   29.07  ? 211 ARG B NH1 1 
ATOM   2769 N NH2 . ARG B 2 41  ? -24.247 6.247   0.94    1   32.27  ? 211 ARG B NH2 1 
ATOM   2770 N N   . ALA B 2 42  ? -22.703 12.855  -0.13   1   29.48  ? 212 ALA B N   1 
ATOM   2771 C CA  . ALA B 2 42  ? -22.328 12.609  -1.506  1   27.25  ? 212 ALA B CA  1 
ATOM   2772 C C   . ALA B 2 42  ? -20.895 13.087  -1.72   1   29.35  ? 212 ALA B C   1 
ATOM   2773 O O   . ALA B 2 42  ? -20.107 12.397  -2.361  1   32.83  ? 212 ALA B O   1 
ATOM   2774 C CB  . ALA B 2 42  ? -23.302 13.325  -2.406  1   25.5   ? 212 ALA B CB  1 
ATOM   2775 N N   . ILE B 2 43  ? -20.561 14.259  -1.166  1   27.91  ? 213 ILE B N   1 
ATOM   2776 C CA  . ILE B 2 43  ? -19.215 14.787  -1.25   1   29.23  ? 213 ILE B CA  1 
ATOM   2777 C C   . ILE B 2 43  ? -18.23  13.812  -0.584  1   31.65  ? 213 ILE B C   1 
ATOM   2778 O O   . ILE B 2 43  ? -17.114 13.587  -1.09   1   28.95  ? 213 ILE B O   1 
ATOM   2779 C CB  . ILE B 2 43  ? -19.175 16.206  -0.646  1   29.67  ? 213 ILE B CB  1 
ATOM   2780 C CG1 . ILE B 2 43  ? -19.974 17.212  -1.5    1   25.21  ? 213 ILE B CG1 1 
ATOM   2781 C CG2 . ILE B 2 43  ? -17.735 16.671  -0.366  1   24.77  ? 213 ILE B CG2 1 
ATOM   2782 C CD1 . ILE B 2 43  ? -20.044 18.616  -0.929  1   22.1   ? 213 ILE B CD1 1 
ATOM   2783 N N   . LEU B 2 44  ? -18.665 13.226  0.543   1   29.68  ? 214 LEU B N   1 
ATOM   2784 C CA  . LEU B 2 44  ? -17.838 12.318  1.328   1   28.1   ? 214 LEU B CA  1 
ATOM   2785 C C   . LEU B 2 44  ? -17.563 11.059  0.515   1   30.23  ? 214 LEU B C   1 
ATOM   2786 O O   . LEU B 2 44  ? -16.416 10.602  0.398   1   29.27  ? 214 LEU B O   1 
ATOM   2787 C CB  . LEU B 2 44  ? -18.492 12.005  2.674   1   24.68  ? 214 LEU B CB  1 
ATOM   2788 C CG  . LEU B 2 44  ? -17.804 10.936  3.535   1   25.6   ? 214 LEU B CG  1 
ATOM   2789 C CD1 . LEU B 2 44  ? -16.47  11.425  4.083   1   23.58  ? 214 LEU B CD1 1 
ATOM   2790 C CD2 . LEU B 2 44  ? -18.703 10.433  4.68    1   23.63  ? 214 LEU B CD2 1 
ATOM   2791 N N   . VAL B 2 45  ? -18.632 10.514  -0.067  1   28.87  ? 215 VAL B N   1 
ATOM   2792 C CA  . VAL B 2 45  ? -18.474 9.255   -0.765  1   33.03  ? 215 VAL B CA  1 
ATOM   2793 C C   . VAL B 2 45  ? -17.577 9.497   -1.983  1   35.91  ? 215 VAL B C   1 
ATOM   2794 O O   . VAL B 2 45  ? -16.668 8.723   -2.275  1   39.31  ? 215 VAL B O   1 
ATOM   2795 C CB  . VAL B 2 45  ? -19.832 8.599   -1.093  1   31.89  ? 215 VAL B CB  1 
ATOM   2796 C CG1 . VAL B 2 45  ? -19.645 7.271   -1.802  1   26.98  ? 215 VAL B CG1 1 
ATOM   2797 C CG2 . VAL B 2 45  ? -20.687 8.406   0.167   1   30.56  ? 215 VAL B CG2 1 
ATOM   2798 N N   . ASP B 2 46  ? -17.821 10.607  -2.68   1   33.61  ? 216 ASP B N   1 
ATOM   2799 C CA  . ASP B 2 46  ? -17.059 10.933  -3.863  1   31.44  ? 216 ASP B CA  1 
ATOM   2800 C C   . ASP B 2 46  ? -15.577 10.96   -3.5    1   32.04  ? 216 ASP B C   1 
ATOM   2801 O O   . ASP B 2 46  ? -14.753 10.387  -4.209  1   33.63  ? 216 ASP B O   1 
ATOM   2802 C CB  . ASP B 2 46  ? -17.527 12.245  -4.461  1   34.58  ? 216 ASP B CB  1 
ATOM   2803 C CG  . ASP B 2 46  ? -16.865 12.585  -5.785  1   36.78  ? 216 ASP B CG  1 
ATOM   2804 O OD1 . ASP B 2 46  ? -17.195 11.933  -6.804  1   36.73  ? 216 ASP B OD1 1 
ATOM   2805 O OD2 . ASP B 2 46  ? -15.978 13.451  -5.767  1   36.87  ? 216 ASP B OD2 1 
ATOM   2806 N N   . TRP B 2 47  ? -15.252 11.605  -2.376  1   29.08  ? 217 TRP B N   1 
ATOM   2807 C CA  . TRP B 2 47  ? -13.881 11.708  -1.909  1   26.08  ? 217 TRP B CA  1 
ATOM   2808 C C   . TRP B 2 47  ? -13.301 10.33   -1.567  1   29.39  ? 217 TRP B C   1 
ATOM   2809 O O   . TRP B 2 47  ? -12.112 10.07   -1.814  1   31.31  ? 217 TRP B O   1 
ATOM   2810 C CB  . TRP B 2 47  ? -13.837 12.678  -0.729  1   24.56  ? 217 TRP B CB  1 
ATOM   2811 C CG  . TRP B 2 47  ? -12.528 12.708  -0.001  1   24.55  ? 217 TRP B CG  1 
ATOM   2812 C CD1 . TRP B 2 47  ? -11.387 13.336  -0.406  1   25.27  ? 217 TRP B CD1 1 
ATOM   2813 C CD2 . TRP B 2 47  ? -12.222 12.078  1.255   1   22.97  ? 217 TRP B CD2 1 
ATOM   2814 N NE1 . TRP B 2 47  ? -10.388 13.128  0.505   1   25.22  ? 217 TRP B NE1 1 
ATOM   2815 C CE2 . TRP B 2 47  ? -10.873 12.363  1.534   1   25.66  ? 217 TRP B CE2 1 
ATOM   2816 C CE3 . TRP B 2 47  ? -12.947 11.311  2.159   1   26.92  ? 217 TRP B CE3 1 
ATOM   2817 C CZ2 . TRP B 2 47  ? -10.237 11.912  2.685   1   29.27  ? 217 TRP B CZ2 1 
ATOM   2818 C CZ3 . TRP B 2 47  ? -12.311 10.841  3.287   1   29.62  ? 217 TRP B CZ3 1 
ATOM   2819 C CH2 . TRP B 2 47  ? -10.978 11.144  3.553   1   29.18  ? 217 TRP B CH2 1 
ATOM   2820 N N   . LEU B 2 48  ? -14.134 9.429   -1.033  1   26.18  ? 218 LEU B N   1 
ATOM   2821 C CA  . LEU B 2 48  ? -13.673 8.088   -0.724  1   24.71  ? 218 LEU B CA  1 
ATOM   2822 C C   . LEU B 2 48  ? -13.423 7.302   -1.998  1   28.02  ? 218 LEU B C   1 
ATOM   2823 O O   . LEU B 2 48  ? -12.632 6.373   -1.942  1   35.49  ? 218 LEU B O   1 
ATOM   2824 C CB  . LEU B 2 48  ? -14.664 7.344   0.161   1   26.25  ? 218 LEU B CB  1 
ATOM   2825 C CG  . LEU B 2 48  ? -14.777 7.867   1.591   1   24.81  ? 218 LEU B CG  1 
ATOM   2826 C CD1 . LEU B 2 48  ? -15.942 7.192   2.281   1   24.58  ? 218 LEU B CD1 1 
ATOM   2827 C CD2 . LEU B 2 48  ? -13.448 7.65    2.306   1   24.26  ? 218 LEU B CD2 1 
ATOM   2828 N N   . VAL B 2 49  ? -14.097 7.643   -3.108  1   24.53  ? 219 VAL B N   1 
ATOM   2829 C CA  . VAL B 2 49  ? -13.803 7.055   -4.407  1   23.64  ? 219 VAL B CA  1 
ATOM   2830 C C   . VAL B 2 49  ? -12.403 7.487   -4.834  1   27.91  ? 219 VAL B C   1 
ATOM   2831 O O   . VAL B 2 49  ? -11.621 6.675   -5.321  1   28.24  ? 219 VAL B O   1 
ATOM   2832 C CB  . VAL B 2 49  ? -14.85  7.428   -5.47   1   21.71  ? 219 VAL B CB  1 
ATOM   2833 C CG1 . VAL B 2 49  ? -14.454 6.954   -6.853  1   21.58  ? 219 VAL B CG1 1 
ATOM   2834 C CG2 . VAL B 2 49  ? -16.213 6.851   -5.105  1   22.68  ? 219 VAL B CG2 1 
ATOM   2835 N N   . GLU B 2 50  ? -12.088 8.77    -4.625  1   31.25  ? 220 GLU B N   1 
ATOM   2836 C CA  . GLU B 2 50  ? -10.773 9.282   -4.955  1   37.85  ? 220 GLU B CA  1 
ATOM   2837 C C   . GLU B 2 50  ? -9.707  8.632   -4.076  1   36.72  ? 220 GLU B C   1 
ATOM   2838 O O   . GLU B 2 50  ? -8.628  8.34    -4.579  1   38.9   ? 220 GLU B O   1 
ATOM   2839 C CB  . GLU B 2 50  ? -10.653 10.793  -4.776  1   43.8   ? 220 GLU B CB  1 
ATOM   2840 C CG  . GLU B 2 50  ? -11.065 11.581  -6.011  1   51.18  ? 220 GLU B CG  1 
ATOM   2841 C CD  . GLU B 2 50  ? -10.972 13.077  -5.784  1   54.97  ? 220 GLU B CD  1 
ATOM   2842 O OE1 . GLU B 2 50  ? -10.663 13.806  -6.765  1   56.84  ? 220 GLU B OE1 1 
ATOM   2843 O OE2 . GLU B 2 50  ? -11.178 13.491  -4.611  1   56.2   ? 220 GLU B OE2 1 
ATOM   2844 N N   . VAL B 2 51  ? -9.991  8.45    -2.777  1   31.48  ? 221 VAL B N   1 
ATOM   2845 C CA  . VAL B 2 51  ? -9.009  7.871   -1.876  1   29.91  ? 221 VAL B CA  1 
ATOM   2846 C C   . VAL B 2 51  ? -8.706  6.442   -2.323  1   33.03  ? 221 VAL B C   1 
ATOM   2847 O O   . VAL B 2 51  ? -7.527  6.07    -2.41   1   34.68  ? 221 VAL B O   1 
ATOM   2848 C CB  . VAL B 2 51  ? -9.429  7.954   -0.396  1   29.11  ? 221 VAL B CB  1 
ATOM   2849 C CG1 . VAL B 2 51  ? -8.483  7.183   0.53    1   25.55  ? 221 VAL B CG1 1 
ATOM   2850 C CG2 . VAL B 2 51  ? -9.602  9.399   0.041   1   25.49  ? 221 VAL B CG2 1 
ATOM   2851 N N   . GLY B 2 52  ? -9.77   5.671   -2.623  1   30.17  ? 222 GLY B N   1 
ATOM   2852 C CA  . GLY B 2 52  ? -9.642  4.324   -3.159  1   30.33  ? 222 GLY B CA  1 
ATOM   2853 C C   . GLY B 2 52  ? -8.726  4.308   -4.386  1   33.37  ? 222 GLY B C   1 
ATOM   2854 O O   . GLY B 2 52  ? -7.971  3.354   -4.573  1   33.1   ? 222 GLY B O   1 
ATOM   2855 N N   . GLU B 2 53  ? -8.806  5.365   -5.21   1   36.01  ? 223 GLU B N   1 
ATOM   2856 C CA  . GLU B 2 53  ? -8.047  5.496   -6.447  1   38.88  ? 223 GLU B CA  1 
ATOM   2857 C C   . GLU B 2 53  ? -6.593  5.851   -6.163  1   42.51  ? 223 GLU B C   1 
ATOM   2858 O O   . GLU B 2 53  ? -5.675  5.294   -6.763  1   42.72  ? 223 GLU B O   1 
ATOM   2859 C CB  . GLU B 2 53  ? -8.66   6.539   -7.381  1   41.08  ? 223 GLU B CB  1 
ATOM   2860 C CG  . GLU B 2 53  ? -9.827  5.992   -8.195  1   47.48  ? 223 GLU B CG  1 
ATOM   2861 C CD  . GLU B 2 53  ? -9.655  4.545   -8.642  1   59.41  ? 223 GLU B CD  1 
ATOM   2862 O OE1 . GLU B 2 53  ? -9.965  3.601   -7.869  1   63.12  ? 223 GLU B OE1 1 
ATOM   2863 O OE2 . GLU B 2 53  ? -9.17   4.364   -9.776  1   69.12  ? 223 GLU B OE2 1 
ATOM   2864 N N   . GLU B 2 54  ? -6.399  6.799   -5.246  1   44.06  ? 224 GLU B N   1 
ATOM   2865 C CA  . GLU B 2 54  ? -5.07   7.239   -4.873  1   43.24  ? 224 GLU B CA  1 
ATOM   2866 C C   . GLU B 2 54  ? -4.273  6.057   -4.323  1   42.01  ? 224 GLU B C   1 
ATOM   2867 O O   . GLU B 2 54  ? -3.085  5.959   -4.595  1   42.82  ? 224 GLU B O   1 
ATOM   2868 C CB  . GLU B 2 54  ? -5.211  8.372   -3.859  1   49.66  ? 224 GLU B CB  1 
ATOM   2869 C CG  . GLU B 2 54  ? -3.92   8.716   -3.12   1   57.29  ? 224 GLU B CG  1 
ATOM   2870 C CD  . GLU B 2 54  ? -2.959  9.572   -3.935  1   63.5   ? 224 GLU B CD  1 
ATOM   2871 O OE1 . GLU B 2 54  ? -3.355  10.059  -5.024  1   62.86  ? 224 GLU B OE1 1 
ATOM   2872 O OE2 . GLU B 2 54  ? -1.801  9.752   -3.478  1   64.42  ? 224 GLU B OE2 1 
ATOM   2873 N N   . TYR B 2 55  ? -4.914  5.191   -3.528  1   38.55  ? 225 TYR B N   1 
ATOM   2874 C CA  . TYR B 2 55  ? -4.215  4.107   -2.852  1   35.07  ? 225 TYR B CA  1 
ATOM   2875 C C   . TYR B 2 55  ? -4.457  2.765   -3.531  1   32.8   ? 225 TYR B C   1 
ATOM   2876 O O   . TYR B 2 55  ? -4.018  1.737   -3.024  1   30.8   ? 225 TYR B O   1 
ATOM   2877 C CB  . TYR B 2 55  ? -4.58   4.074   -1.37   1   32.37  ? 225 TYR B CB  1 
ATOM   2878 C CG  . TYR B 2 55  ? -4.037  5.288   -0.64   1   37.33  ? 225 TYR B CG  1 
ATOM   2879 C CD1 . TYR B 2 55  ? -2.684  5.394   -0.329  1   37.81  ? 225 TYR B CD1 1 
ATOM   2880 C CD2 . TYR B 2 55  ? -4.879  6.329   -0.272  1   41.85  ? 225 TYR B CD2 1 
ATOM   2881 C CE1 . TYR B 2 55  ? -2.192  6.505   0.342   1   41.29  ? 225 TYR B CE1 1 
ATOM   2882 C CE2 . TYR B 2 55  ? -4.393  7.445   0.391   1   40.62  ? 225 TYR B CE2 1 
ATOM   2883 C CZ  . TYR B 2 55  ? -3.044  7.544   0.679   1   39.16  ? 225 TYR B CZ  1 
ATOM   2884 O OH  . TYR B 2 55  ? -2.558  8.64    1.33    1   40.63  ? 225 TYR B OH  1 
ATOM   2885 N N   . LYS B 2 56  ? -5.15   2.803   -4.671  1   34.86  ? 226 LYS B N   1 
ATOM   2886 C CA  . LYS B 2 56  ? -5.393  1.621   -5.488  1   35.42  ? 226 LYS B CA  1 
ATOM   2887 C C   . LYS B 2 56  ? -6.059  0.536   -4.641  1   34.6   ? 226 LYS B C   1 
ATOM   2888 O O   . LYS B 2 56  ? -5.634  -0.611  -4.666  1   35.78  ? 226 LYS B O   1 
ATOM   2889 C CB  . LYS B 2 56  ? -4.122  1.207   -6.254  1   38.8   ? 226 LYS B CB  1 
ATOM   2890 C CG  . LYS B 2 56  ? -3.399  2.333   -7.027  1   49.55  ? 226 LYS B CG  1 
ATOM   2891 C CD  . LYS B 2 56  ? -3.436  2.401   -8.565  1   68.36  ? 226 LYS B CD  1 
ATOM   2892 C CE  . LYS B 2 56  ? -2.73   1.386   -9.424  1   73.85  ? 226 LYS B CE  1 
ATOM   2893 N NZ  . LYS B 2 56  ? -1.281  1.515   -9.275  1   70.42  ? 226 LYS B NZ  1 
ATOM   2894 N N   . LEU B 2 57  ? -7.1    0.915   -3.885  1   31.1   ? 227 LEU B N   1 
ATOM   2895 C CA  . LEU B 2 57  ? -7.836  -0.021  -3.054  1   29.53  ? 227 LEU B CA  1 
ATOM   2896 C C   . LEU B 2 57  ? -8.843  -0.763  -3.918  1   28.73  ? 227 LEU B C   1 
ATOM   2897 O O   . LEU B 2 57  ? -9.268  -0.256  -4.955  1   30.7   ? 227 LEU B O   1 
ATOM   2898 C CB  . LEU B 2 57  ? -8.577  0.727   -1.946  1   28.41  ? 227 LEU B CB  1 
ATOM   2899 C CG  . LEU B 2 57  ? -7.726  1.646   -1.066  1   27.09  ? 227 LEU B CG  1 
ATOM   2900 C CD1 . LEU B 2 57  ? -8.624  2.247   -0.025  1   25.93  ? 227 LEU B CD1 1 
ATOM   2901 C CD2 . LEU B 2 57  ? -6.558  0.904   -0.428  1   26.43  ? 227 LEU B CD2 1 
ATOM   2902 N N   . GLN B 2 58  ? -9.242  -1.942  -3.44   1   27.65  ? 228 GLN B N   1 
ATOM   2903 C CA  . GLN B 2 58  ? -10.334 -2.709  -4.013  1   27.69  ? 228 GLN B CA  1 
ATOM   2904 C C   . GLN B 2 58  ? -11.635 -1.908  -3.974  1   27.98  ? 228 GLN B C   1 
ATOM   2905 O O   . GLN B 2 58  ? -11.919 -1.177  -3.013  1   29.41  ? 228 GLN B O   1 
ATOM   2906 C CB  . GLN B 2 58  ? -10.519 -3.979  -3.175  1   26.36  ? 228 GLN B CB  1 
ATOM   2907 C CG  . GLN B 2 58  ? -9.364  -4.971  -3.229  1   30.98  ? 228 GLN B CG  1 
ATOM   2908 C CD  . GLN B 2 58  ? -9.02   -5.327  -4.662  1   34.49  ? 228 GLN B CD  1 
ATOM   2909 O OE1 . GLN B 2 58  ? -9.874  -5.808  -5.418  1   31.63  ? 228 GLN B OE1 1 
ATOM   2910 N NE2 . GLN B 2 58  ? -7.805  -4.985  -5.071  1   28.37  ? 228 GLN B NE2 1 
ATOM   2911 N N   . ASN B 2 59  ? -12.473 -2.134  -4.986  1   28.56  ? 229 ASN B N   1 
ATOM   2912 C CA  . ASN B 2 59  ? -13.806 -1.559  -4.989  1   29.86  ? 229 ASN B CA  1 
ATOM   2913 C C   . ASN B 2 59  ? -14.627 -2.123  -3.829  1   33.48  ? 229 ASN B C   1 
ATOM   2914 O O   . ASN B 2 59  ? -15.479 -1.41   -3.27   1   36     ? 229 ASN B O   1 
ATOM   2915 C CB  . ASN B 2 59  ? -14.54  -1.78   -6.303  1   29.84  ? 229 ASN B CB  1 
ATOM   2916 C CG  . ASN B 2 59  ? -13.928 -1.1    -7.506  1   30.95  ? 229 ASN B CG  1 
ATOM   2917 O OD1 . ASN B 2 59  ? -13.02  -0.265  -7.402  1   30.65  ? 229 ASN B OD1 1 
ATOM   2918 N ND2 . ASN B 2 59  ? -14.438 -1.454  -8.676  1   34.09  ? 229 ASN B ND2 1 
ATOM   2919 N N   . GLU B 2 60  ? -14.389 -3.406  -3.479  1   31.54  ? 230 GLU B N   1 
ATOM   2920 C CA  . GLU B 2 60  ? -15.083 -4.02   -2.352  1   28.52  ? 230 GLU B CA  1 
ATOM   2921 C C   . GLU B 2 60  ? -14.86  -3.165  -1.103  1   31.9   ? 230 GLU B C   1 
ATOM   2922 O O   . GLU B 2 60  ? -15.795 -2.964  -0.313  1   27.77  ? 230 GLU B O   1 
ATOM   2923 C CB  . GLU B 2 60  ? -14.647 -5.465  -2.115  1   24.93  ? 230 GLU B CB  1 
ATOM   2924 C CG  . GLU B 2 60  ? -15.337 -6.174  -0.95   1   22.88  ? 230 GLU B CG  1 
ATOM   2925 C CD  . GLU B 2 60  ? -16.853 -6.357  -1.071  1   26.57  ? 230 GLU B CD  1 
ATOM   2926 O OE1 . GLU B 2 60  ? -17.442 -6.094  -2.146  1   24.82  ? 230 GLU B OE1 1 
ATOM   2927 O OE2 . GLU B 2 60  ? -17.468 -6.79   -0.071  1   24.27  ? 230 GLU B OE2 1 
ATOM   2928 N N   . THR B 2 61  ? -13.623 -2.655  -0.954  1   27.36  ? 231 THR B N   1 
ATOM   2929 C CA  . THR B 2 61  ? -13.269 -1.877  0.223   1   30.68  ? 231 THR B CA  1 
ATOM   2930 C C   . THR B 2 61  ? -14.133 -0.61   0.291   1   31.59  ? 231 THR B C   1 
ATOM   2931 O O   . THR B 2 61  ? -14.645 -0.255  1.345   1   30.92  ? 231 THR B O   1 
ATOM   2932 C CB  . THR B 2 61  ? -11.769 -1.569  0.203   1   29.85  ? 231 THR B CB  1 
ATOM   2933 O OG1 . THR B 2 61  ? -11.037 -2.787  0.108   1   25.52  ? 231 THR B OG1 1 
ATOM   2934 C CG2 . THR B 2 61  ? -11.328 -0.806  1.437   1   27.26  ? 231 THR B CG2 1 
ATOM   2935 N N   . LEU B 2 62  ? -14.288 0.065   -0.854  1   32.68  ? 232 LEU B N   1 
ATOM   2936 C CA  . LEU B 2 62  ? -15.072 1.281   -0.943  1   28.83  ? 232 LEU B CA  1 
ATOM   2937 C C   . LEU B 2 62  ? -16.499 0.976   -0.529  1   27.49  ? 232 LEU B C   1 
ATOM   2938 O O   . LEU B 2 62  ? -17.055 1.717   0.27    1   30.95  ? 232 LEU B O   1 
ATOM   2939 C CB  . LEU B 2 62  ? -15.033 1.829   -2.367  1   28.11  ? 232 LEU B CB  1 
ATOM   2940 C CG  . LEU B 2 62  ? -16.037 2.943   -2.676  1   23.75  ? 232 LEU B CG  1 
ATOM   2941 C CD1 . LEU B 2 62  ? -15.707 4.254   -1.926  1   22.02  ? 232 LEU B CD1 1 
ATOM   2942 C CD2 . LEU B 2 62  ? -16.086 3.148   -4.174  1   22.47  ? 232 LEU B CD2 1 
ATOM   2943 N N   . HIS B 2 63  ? -17.069 -0.114  -1.067  1   26.84  ? 233 HIS B N   1 
ATOM   2944 C CA  . HIS B 2 63  ? -18.443 -0.501  -0.74   1   25.2   ? 233 HIS B CA  1 
ATOM   2945 C C   . HIS B 2 63  ? -18.614 -0.791  0.757   1   27.96  ? 233 HIS B C   1 
ATOM   2946 O O   . HIS B 2 63  ? -19.612 -0.39   1.352   1   27.46  ? 233 HIS B O   1 
ATOM   2947 C CB  . HIS B 2 63  ? -18.901 -1.709  -1.553  1   22.8   ? 233 HIS B CB  1 
ATOM   2948 C CG  . HIS B 2 63  ? -19.344 -1.396  -2.949  1   27.57  ? 233 HIS B CG  1 
ATOM   2949 N ND1 . HIS B 2 63  ? -18.486 -1.15   -4.011  1   27.42  ? 233 HIS B ND1 1 
ATOM   2950 C CD2 . HIS B 2 63  ? -20.593 -1.286  -3.443  1   26.67  ? 233 HIS B CD2 1 
ATOM   2951 C CE1 . HIS B 2 63  ? -19.202 -0.894  -5.098  1   25.71  ? 233 HIS B CE1 1 
ATOM   2952 N NE2 . HIS B 2 63  ? -20.474 -0.988  -4.778  1   27.73  ? 233 HIS B NE2 1 
ATOM   2953 N N   . LEU B 2 64  ? -17.651 -1.498  1.369   1   27.43  ? 234 LEU B N   1 
ATOM   2954 C CA  . LEU B 2 64  ? -17.743 -1.785  2.787   1   26.2   ? 234 LEU B CA  1 
ATOM   2955 C C   . LEU B 2 64  ? -17.775 -0.461  3.544   1   28.97  ? 234 LEU B C   1 
ATOM   2956 O O   . LEU B 2 64  ? -18.618 -0.26   4.417   1   28.04  ? 234 LEU B O   1 
ATOM   2957 C CB  . LEU B 2 64  ? -16.567 -2.646  3.236   1   24.28  ? 234 LEU B CB  1 
ATOM   2958 C CG  . LEU B 2 64  ? -16.59  -4.087  2.724   1   23.8   ? 234 LEU B CG  1 
ATOM   2959 C CD1 . LEU B 2 64  ? -15.272 -4.764  3.064   1   20.61  ? 234 LEU B CD1 1 
ATOM   2960 C CD2 . LEU B 2 64  ? -17.804 -4.878  3.243   1   22.53  ? 234 LEU B CD2 1 
ATOM   2961 N N   . ALA B 2 65  ? -16.85  0.435   3.193   1   26.78  ? 235 ALA B N   1 
ATOM   2962 C CA  . ALA B 2 65  ? -16.737 1.7     3.893   1   26.36  ? 235 ALA B CA  1 
ATOM   2963 C C   . ALA B 2 65  ? -18.087 2.427   3.911   1   27.56  ? 235 ALA B C   1 
ATOM   2964 O O   . ALA B 2 65  ? -18.565 2.865   4.966   1   32.84  ? 235 ALA B O   1 
ATOM   2965 C CB  . ALA B 2 65  ? -15.617 2.523   3.291   1   21.03  ? 235 ALA B CB  1 
ATOM   2966 N N   . VAL B 2 66  ? -18.719 2.554   2.741   1   27.98  ? 236 VAL B N   1 
ATOM   2967 C CA  . VAL B 2 66  ? -19.989 3.264   2.651   1   25.86  ? 236 VAL B CA  1 
ATOM   2968 C C   . VAL B 2 66  ? -21.009 2.584   3.568   1   28.37  ? 236 VAL B C   1 
ATOM   2969 O O   . VAL B 2 66  ? -21.758 3.266   4.274   1   36.27  ? 236 VAL B O   1 
ATOM   2970 C CB  . VAL B 2 66  ? -20.439 3.359   1.182   1   25.22  ? 236 VAL B CB  1 
ATOM   2971 C CG1 . VAL B 2 66  ? -21.844 3.934   1.033   1   29.12  ? 236 VAL B CG1 1 
ATOM   2972 C CG2 . VAL B 2 66  ? -19.448 4.166   0.356   1   24.46  ? 236 VAL B CG2 1 
ATOM   2973 N N   . ASN B 2 67  ? -21.007 1.24    3.604   1   25.61  ? 237 ASN B N   1 
ATOM   2974 C CA  . ASN B 2 67  ? -21.931 0.494   4.452   1   24.95  ? 237 ASN B CA  1 
ATOM   2975 C C   . ASN B 2 67  ? -21.714 0.872   5.912   1   26.64  ? 237 ASN B C   1 
ATOM   2976 O O   . ASN B 2 67  ? -22.686 1.019   6.648   1   27.3   ? 237 ASN B O   1 
ATOM   2977 C CB  . ASN B 2 67  ? -21.835 -1.015  4.234   1   26.66  ? 237 ASN B CB  1 
ATOM   2978 C CG  . ASN B 2 67  ? -22.683 -1.797  5.209   1   30.5   ? 237 ASN B CG  1 
ATOM   2979 O OD1 . ASN B 2 67  ? -22.256 -2.093  6.327   1   40.5   ? 237 ASN B OD1 1 
ATOM   2980 N ND2 . ASN B 2 67  ? -23.89  -2.145  4.822   1   31.19  ? 237 ASN B ND2 1 
ATOM   2981 N N   . TYR B 2 68  ? -20.44  0.986   6.327   1   25.79  ? 238 TYR B N   1 
ATOM   2982 C CA  . TYR B 2 68  ? -20.09  1.254   7.711   1   25.68  ? 238 TYR B CA  1 
ATOM   2983 C C   . TYR B 2 68  ? -20.576 2.651   8.07    1   28.59  ? 238 TYR B C   1 
ATOM   2984 O O   . TYR B 2 68  ? -21.106 2.855   9.173   1   27.98  ? 238 TYR B O   1 
ATOM   2985 C CB  . TYR B 2 68  ? -18.585 1.139   7.995   1   25.27  ? 238 TYR B CB  1 
ATOM   2986 C CG  . TYR B 2 68  ? -17.988 -0.241  7.732   1   24.98  ? 238 TYR B CG  1 
ATOM   2987 C CD1 . TYR B 2 68  ? -18.783 -1.385  7.61    1   24.08  ? 238 TYR B CD1 1 
ATOM   2988 C CD2 . TYR B 2 68  ? -16.628 -0.387  7.569   1   22.08  ? 238 TYR B CD2 1 
ATOM   2989 C CE1 . TYR B 2 68  ? -18.234 -2.631  7.357   1   22.84  ? 238 TYR B CE1 1 
ATOM   2990 C CE2 . TYR B 2 68  ? -16.068 -1.623  7.308   1   22.78  ? 238 TYR B CE2 1 
ATOM   2991 C CZ  . TYR B 2 68  ? -16.865 -2.747  7.197   1   24.24  ? 238 TYR B CZ  1 
ATOM   2992 O OH  . TYR B 2 68  ? -16.259 -3.944  6.907   1   25.96  ? 238 TYR B OH  1 
ATOM   2993 N N   . ILE B 2 69  ? -20.373 3.582   7.119   1   28.04  ? 239 ILE B N   1 
ATOM   2994 C CA  . ILE B 2 69  ? -20.733 4.974   7.317   1   28.56  ? 239 ILE B CA  1 
ATOM   2995 C C   . ILE B 2 69  ? -22.242 5.067   7.503   1   31.18  ? 239 ILE B C   1 
ATOM   2996 O O   . ILE B 2 69  ? -22.686 5.684   8.482   1   30.03  ? 239 ILE B O   1 
ATOM   2997 C CB  . ILE B 2 69  ? -20.261 5.871   6.155   1   28.95  ? 239 ILE B CB  1 
ATOM   2998 C CG1 . ILE B 2 69  ? -18.735 5.956   6.061   1   26.88  ? 239 ILE B CG1 1 
ATOM   2999 C CG2 . ILE B 2 69  ? -20.894 7.262   6.26    1   23.47  ? 239 ILE B CG2 1 
ATOM   3000 C CD1 . ILE B 2 69  ? -18.228 6.406   4.699   1   26.63  ? 239 ILE B CD1 1 
ATOM   3001 N N   . ASP B 2 70  ? -23.008 4.449   6.576   1   28     ? 240 ASP B N   1 
ATOM   3002 C CA  . ASP B 2 70  ? -24.458 4.624   6.587   1   28.32  ? 240 ASP B CA  1 
ATOM   3003 C C   . ASP B 2 70  ? -25.058 4.002   7.846   1   30     ? 240 ASP B C   1 
ATOM   3004 O O   . ASP B 2 70  ? -25.966 4.586   8.428   1   28.49  ? 240 ASP B O   1 
ATOM   3005 C CB  . ASP B 2 70  ? -25.137 4.105   5.328   1   28.69  ? 240 ASP B CB  1 
ATOM   3006 C CG  . ASP B 2 70  ? -24.919 4.918   4.065   1   28.92  ? 240 ASP B CG  1 
ATOM   3007 O OD1 . ASP B 2 70  ? -24.835 6.142   4.181   1   30.38  ? 240 ASP B OD1 1 
ATOM   3008 O OD2 . ASP B 2 70  ? -24.878 4.323   2.975   1   30.92  ? 240 ASP B OD2 1 
ATOM   3009 N N   . ARG B 2 71  ? -24.541 2.834   8.27    1   29.04  ? 241 ARG B N   1 
ATOM   3010 C CA  . ARG B 2 71  ? -24.976 2.213   9.512   1   29.01  ? 241 ARG B CA  1 
ATOM   3011 C C   . ARG B 2 71  ? -24.622 3.1     10.702  1   30.02  ? 241 ARG B C   1 
ATOM   3012 O O   . ARG B 2 71  ? -25.416 3.234   11.632  1   31.91  ? 241 ARG B O   1 
ATOM   3013 C CB  . ARG B 2 71  ? -24.381 0.815   9.723   1   27.71  ? 241 ARG B CB  1 
ATOM   3014 C CG  . ARG B 2 71  ? -25.087 -0.271  8.924   1   25.17  ? 241 ARG B CG  1 
ATOM   3015 C CD  . ARG B 2 71  ? -24.149 -1.4    8.54    1   24.21  ? 241 ARG B CD  1 
ATOM   3016 N NE  . ARG B 2 71  ? -23.965 -2.333  9.648   1   23.66  ? 241 ARG B NE  1 
ATOM   3017 C CZ  . ARG B 2 71  ? -22.977 -3.207  9.761   1   22.75  ? 241 ARG B CZ  1 
ATOM   3018 N NH1 . ARG B 2 71  ? -22.061 -3.352  8.826   1   23.2   ? 241 ARG B NH1 1 
ATOM   3019 N NH2 . ARG B 2 71  ? -22.909 -3.939  10.839  1   22.2   ? 241 ARG B NH2 1 
ATOM   3020 N N   . PHE B 2 72  ? -23.422 3.694   10.69   1   27.41  ? 242 PHE B N   1 
ATOM   3021 C CA  . PHE B 2 72  ? -23.018 4.525   11.815  1   25.49  ? 242 PHE B CA  1 
ATOM   3022 C C   . PHE B 2 72  ? -23.95  5.734   11.94   1   27.09  ? 242 PHE B C   1 
ATOM   3023 O O   . PHE B 2 72  ? -24.425 6.063   13.026  1   27.48  ? 242 PHE B O   1 
ATOM   3024 C CB  . PHE B 2 72  ? -21.564 4.948   11.634  1   22.28  ? 242 PHE B CB  1 
ATOM   3025 C CG  . PHE B 2 72  ? -21.015 5.757   12.789  1   21.85  ? 242 PHE B CG  1 
ATOM   3026 C CD1 . PHE B 2 72  ? -21.119 7.14    12.81   1   22.45  ? 242 PHE B CD1 1 
ATOM   3027 C CD2 . PHE B 2 72  ? -20.357 5.131   13.836  1   24.25  ? 242 PHE B CD2 1 
ATOM   3028 C CE1 . PHE B 2 72  ? -20.583 7.883   13.856  1   21.56  ? 242 PHE B CE1 1 
ATOM   3029 C CE2 . PHE B 2 72  ? -19.833 5.877   14.889  1   25.55  ? 242 PHE B CE2 1 
ATOM   3030 C CZ  . PHE B 2 72  ? -19.929 7.249   14.886  1   22.52  ? 242 PHE B CZ  1 
ATOM   3031 N N   . LEU B 2 73  ? -24.217 6.397   10.812  1   29.08  ? 243 LEU B N   1 
ATOM   3032 C CA  . LEU B 2 73  ? -25.006 7.622   10.788  1   29.34  ? 243 LEU B CA  1 
ATOM   3033 C C   . LEU B 2 73  ? -26.469 7.306   11.07   1   29.66  ? 243 LEU B C   1 
ATOM   3034 O O   . LEU B 2 73  ? -27.261 8.23    11.226  1   31.38  ? 243 LEU B O   1 
ATOM   3035 C CB  . LEU B 2 73  ? -24.873 8.325   9.436   1   28.27  ? 243 LEU B CB  1 
ATOM   3036 C CG  . LEU B 2 73  ? -23.494 8.913   9.114   1   28.16  ? 243 LEU B CG  1 
ATOM   3037 C CD1 . LEU B 2 73  ? -23.531 9.543   7.744   1   24.71  ? 243 LEU B CD1 1 
ATOM   3038 C CD2 . LEU B 2 73  ? -23.015 9.899   10.191  1   28.93  ? 243 LEU B CD2 1 
ATOM   3039 N N   . SER B 2 74  ? -26.806 6.01    11.125  1   28.46  ? 244 SER B N   1 
ATOM   3040 C CA  . SER B 2 74  ? -28.163 5.559   11.395  1   28.59  ? 244 SER B CA  1 
ATOM   3041 C C   . SER B 2 74  ? -28.462 5.68    12.884  1   28.73  ? 244 SER B C   1 
ATOM   3042 O O   . SER B 2 74  ? -29.619 5.888   13.266  1   25.55  ? 244 SER B O   1 
ATOM   3043 C CB  . SER B 2 74  ? -28.409 4.155   10.903  1   24.99  ? 244 SER B CB  1 
ATOM   3044 O OG  . SER B 2 74  ? -28.653 4.189   9.508   1   27.68  ? 244 SER B OG  1 
ATOM   3045 N N   . SER B 2 75  ? -27.41  5.582   13.715  1   27.96  ? 245 SER B N   1 
ATOM   3046 C CA  . SER B 2 75  ? -27.651 5.69    15.147  1   26.65  ? 245 SER B CA  1 
ATOM   3047 C C   . SER B 2 75  ? -26.887 6.838   15.808  1   26.18  ? 245 SER B C   1 
ATOM   3048 O O   . SER B 2 75  ? -27.203 7.186   16.944  1   27.62  ? 245 SER B O   1 
ATOM   3049 C CB  . SER B 2 75  ? -27.433 4.387   15.839  1   23.92  ? 245 SER B CB  1 
ATOM   3050 O OG  . SER B 2 75  ? -26.053 4.122   15.92   1   25.44  ? 245 SER B OG  1 
ATOM   3051 N N   . MET B 2 76  ? -25.898 7.423   15.112  1   25.57  ? 246 MET B N   1 
ATOM   3052 C CA  . MET B 2 76  ? -25.062 8.46    15.707  1   24.5   ? 246 MET B CA  1 
ATOM   3053 C C   . MET B 2 76  ? -25.206 9.772   14.941  1   25.92  ? 246 MET B C   1 
ATOM   3054 O O   . MET B 2 76  ? -25.071 9.832   13.718  1   29.18  ? 246 MET B O   1 
ATOM   3055 C CB  . MET B 2 76  ? -23.584 8.075   15.71   1   21.62  ? 246 MET B CB  1 
ATOM   3056 C CG  . MET B 2 76  ? -23.307 6.762   16.352  1   21.86  ? 246 MET B CG  1 
ATOM   3057 S SD  . MET B 2 76  ? -23.575 6.81    18.131  1   27.46  ? 246 MET B SD  1 
ATOM   3058 C CE  . MET B 2 76  ? -22.067 7.661   18.609  1   25.09  ? 246 MET B CE  1 
ATOM   3059 N N   . SER B 2 77  ? -25.507 10.82   15.697  1   25.16  ? 247 SER B N   1 
ATOM   3060 C CA  . SER B 2 77  ? -25.683 12.153  15.163  1   24.43  ? 247 SER B CA  1 
ATOM   3061 C C   . SER B 2 77  ? -24.29  12.772  15.001  1   24.66  ? 247 SER B C   1 
ATOM   3062 O O   . SER B 2 77  ? -23.443 12.593  15.882  1   22.86  ? 247 SER B O   1 
ATOM   3063 C CB  . SER B 2 77  ? -26.508 12.892  16.158  1   23.88  ? 247 SER B CB  1 
ATOM   3064 O OG  . SER B 2 77  ? -26.716 14.234  15.773  1   30.24  ? 247 SER B OG  1 
ATOM   3065 N N   . VAL B 2 78  ? -24.035 13.46   13.874  1   24.24  ? 248 VAL B N   1 
ATOM   3066 C CA  . VAL B 2 78  ? -22.682 13.896  13.548  1   24.55  ? 248 VAL B CA  1 
ATOM   3067 C C   . VAL B 2 78  ? -22.674 15.309  12.974  1   25.59  ? 248 VAL B C   1 
ATOM   3068 O O   . VAL B 2 78  ? -23.413 15.593  12.041  1   29.55  ? 248 VAL B O   1 
ATOM   3069 C CB  . VAL B 2 78  ? -21.972 12.923  12.593  1   26.57  ? 248 VAL B CB  1 
ATOM   3070 C CG1 . VAL B 2 78  ? -20.538 13.358  12.345  1   26.67  ? 248 VAL B CG1 1 
ATOM   3071 C CG2 . VAL B 2 78  ? -21.959 11.501  13.15   1   29.59  ? 248 VAL B CG2 1 
ATOM   3072 N N   . LEU B 2 79  ? -21.815 16.183  13.523  1   25.47  ? 249 LEU B N   1 
ATOM   3073 C CA  . LEU B 2 79  ? -21.6   17.529  13.01   1   25.04  ? 249 LEU B CA  1 
ATOM   3074 C C   . LEU B 2 79  ? -20.787 17.504  11.708  1   25.61  ? 249 LEU B C   1 
ATOM   3075 O O   . LEU B 2 79  ? -19.872 16.698  11.52   1   22.56  ? 249 LEU B O   1 
ATOM   3076 C CB  . LEU B 2 79  ? -20.932 18.378  14.088  1   27.14  ? 249 LEU B CB  1 
ATOM   3077 C CG  . LEU B 2 79  ? -21.737 18.638  15.365  1   31.94  ? 249 LEU B CG  1 
ATOM   3078 C CD1 . LEU B 2 79  ? -21.095 19.776  16.14   1   30.14  ? 249 LEU B CD1 1 
ATOM   3079 C CD2 . LEU B 2 79  ? -23.214 18.946  15.117  1   34.33  ? 249 LEU B CD2 1 
ATOM   3080 N N   . ARG B 2 80  ? -21.115 18.428  10.806  1   27.29  ? 250 ARG B N   1 
ATOM   3081 C CA  . ARG B 2 80  ? -20.536 18.45   9.468   1   29.26  ? 250 ARG B CA  1 
ATOM   3082 C C   . ARG B 2 80  ? -19.011 18.412  9.559   1   29.17  ? 250 ARG B C   1 
ATOM   3083 O O   . ARG B 2 80  ? -18.38  17.745  8.734   1   28.89  ? 250 ARG B O   1 
ATOM   3084 C CB  . ARG B 2 80  ? -21.041 19.641  8.644   1   29.32  ? 250 ARG B CB  1 
ATOM   3085 C CG  . ARG B 2 80  ? -20.524 20.978  9.156   1   29.54  ? 250 ARG B CG  1 
ATOM   3086 C CD  . ARG B 2 80  ? -21.191 22.18   8.529   1   28.91  ? 250 ARG B CD  1 
ATOM   3087 N NE  . ARG B 2 80  ? -22.643 22.212  8.734   1   32.47  ? 250 ARG B NE  1 
ATOM   3088 C CZ  . ARG B 2 80  ? -23.489 23.04   8.105   1   35.16  ? 250 ARG B CZ  1 
ATOM   3089 N NH1 . ARG B 2 80  ? -23.082 23.915  7.204   1   33.87  ? 250 ARG B NH1 1 
ATOM   3090 N NH2 . ARG B 2 80  ? -24.773 22.983  8.357   1   35.88  ? 250 ARG B NH2 1 
ATOM   3091 N N   . GLY B 2 81  ? -18.45  19.078  10.587  1   26.12  ? 251 GLY B N   1 
ATOM   3092 C CA  . GLY B 2 81  ? -17.016 19.141  10.831  1   23.76  ? 251 GLY B CA  1 
ATOM   3093 C C   . GLY B 2 81  ? -16.373 17.781  11.121  1   24.91  ? 251 GLY B C   1 
ATOM   3094 O O   . GLY B 2 81  ? -15.15  17.661  11.043  1   27.95  ? 251 GLY B O   1 
ATOM   3095 N N   . LYS B 2 82  ? -17.191 16.768  11.453  1   22.53  ? 252 LYS B N   1 
ATOM   3096 C CA  . LYS B 2 82  ? -16.715 15.466  11.889  1   20.65  ? 252 LYS B CA  1 
ATOM   3097 C C   . LYS B 2 82  ? -17.139 14.359  10.923  1   21.09  ? 252 LYS B C   1 
ATOM   3098 O O   . LYS B 2 82  ? -16.777 13.194  11.089  1   22.32  ? 252 LYS B O   1 
ATOM   3099 C CB  . LYS B 2 82  ? -17.252 15.159  13.291  1   20.57  ? 252 LYS B CB  1 
ATOM   3100 C CG  . LYS B 2 82  ? -16.692 15.992  14.432  1   21.44  ? 252 LYS B CG  1 
ATOM   3101 C CD  . LYS B 2 82  ? -15.193 15.757  14.6    1   24.87  ? 252 LYS B CD  1 
ATOM   3102 C CE  . LYS B 2 82  ? -14.616 16.234  15.902  1   26.42  ? 252 LYS B CE  1 
ATOM   3103 N NZ  . LYS B 2 82  ? -14.473 17.689  15.801  1   28.08  ? 252 LYS B NZ  1 
ATOM   3104 N N   . LEU B 2 83  ? -17.901 14.703  9.892   1   21.34  ? 253 LEU B N   1 
ATOM   3105 C CA  . LEU B 2 83  ? -18.319 13.681  8.948   1   25.21  ? 253 LEU B CA  1 
ATOM   3106 C C   . LEU B 2 83  ? -17.099 13.005  8.305   1   27.59  ? 253 LEU B C   1 
ATOM   3107 O O   . LEU B 2 83  ? -17.05  11.777  8.194   1   30.74  ? 253 LEU B O   1 
ATOM   3108 C CB  . LEU B 2 83  ? -19.257 14.289  7.907   1   23.09  ? 253 LEU B CB  1 
ATOM   3109 C CG  . LEU B 2 83  ? -19.792 13.33   6.844   1   23.08  ? 253 LEU B CG  1 
ATOM   3110 C CD1 . LEU B 2 83  ? -20.585 12.165  7.486   1   20.02  ? 253 LEU B CD1 1 
ATOM   3111 C CD2 . LEU B 2 83  ? -20.631 14.127  5.842   1   20.19  ? 253 LEU B CD2 1 
ATOM   3112 N N   . GLN B 2 84  ? -16.107 13.802  7.878   1   27.72  ? 254 GLN B N   1 
ATOM   3113 C CA  . GLN B 2 84  ? -14.915 13.253  7.238   1   29.48  ? 254 GLN B CA  1 
ATOM   3114 C C   . GLN B 2 84  ? -14.172 12.289  8.172   1   28.58  ? 254 GLN B C   1 
ATOM   3115 O O   . GLN B 2 84  ? -13.592 11.312  7.723   1   28.21  ? 254 GLN B O   1 
ATOM   3116 C CB  . GLN B 2 84  ? -13.993 14.343  6.692   1   29.49  ? 254 GLN B CB  1 
ATOM   3117 C CG  . GLN B 2 84  ? -12.878 13.788  5.816   1   29.3   ? 254 GLN B CG  1 
ATOM   3118 C CD  . GLN B 2 84  ? -12.038 14.868  5.179   1   29.61  ? 254 GLN B CD  1 
ATOM   3119 O OE1 . GLN B 2 84  ? -11.504 14.69   4.083   1   30.49  ? 254 GLN B OE1 1 
ATOM   3120 N NE2 . GLN B 2 84  ? -11.861 15.973  5.885   1   29.8   ? 254 GLN B NE2 1 
ATOM   3121 N N   . LEU B 2 85  ? -14.218 12.559  9.478   1   28.08  ? 255 LEU B N   1 
ATOM   3122 C CA  . LEU B 2 85  ? -13.543 11.727  10.454  1   26.79  ? 255 LEU B CA  1 
ATOM   3123 C C   . LEU B 2 85  ? -14.188 10.355  10.521  1   26.31  ? 255 LEU B C   1 
ATOM   3124 O O   . LEU B 2 85  ? -13.479 9.376   10.733  1   26.81  ? 255 LEU B O   1 
ATOM   3125 C CB  . LEU B 2 85  ? -13.558 12.396  11.821  1   25.99  ? 255 LEU B CB  1 
ATOM   3126 C CG  . LEU B 2 85  ? -12.874 11.606  12.942  1   26.3   ? 255 LEU B CG  1 
ATOM   3127 C CD1 . LEU B 2 85  ? -11.433 11.218  12.605  1   25.38  ? 255 LEU B CD1 1 
ATOM   3128 C CD2 . LEU B 2 85  ? -12.946 12.432  14.224  1   25.81  ? 255 LEU B CD2 1 
ATOM   3129 N N   . VAL B 2 86  ? -15.525 10.308  10.386  1   25.9   ? 256 VAL B N   1 
ATOM   3130 C CA  . VAL B 2 86  ? -16.259 9.054   10.394  1   22.65  ? 256 VAL B CA  1 
ATOM   3131 C C   . VAL B 2 86  ? -15.872 8.288   9.134   1   21.61  ? 256 VAL B C   1 
ATOM   3132 O O   . VAL B 2 86  ? -15.511 7.124   9.208   1   22.86  ? 256 VAL B O   1 
ATOM   3133 C CB  . VAL B 2 86  ? -17.785 9.27    10.499  1   25.1   ? 256 VAL B CB  1 
ATOM   3134 C CG1 . VAL B 2 86  ? -18.558 7.967   10.353  1   23.36  ? 256 VAL B CG1 1 
ATOM   3135 C CG2 . VAL B 2 86  ? -18.174 9.979   11.79   1   22.41  ? 256 VAL B CG2 1 
ATOM   3136 N N   . GLY B 2 87  ? -15.928 8.962   7.981   1   22.47  ? 257 GLY B N   1 
ATOM   3137 C CA  . GLY B 2 87  ? -15.534 8.388   6.702   1   24.79  ? 257 GLY B CA  1 
ATOM   3138 C C   . GLY B 2 87  ? -14.114 7.82    6.701   1   25.56  ? 257 GLY B C   1 
ATOM   3139 O O   . GLY B 2 87  ? -13.874 6.731   6.185   1   24.77  ? 257 GLY B O   1 
ATOM   3140 N N   . THR B 2 88  ? -13.165 8.575   7.266   1   27.06  ? 258 THR B N   1 
ATOM   3141 C CA  . THR B 2 88  ? -11.768 8.176   7.312   1   27.34  ? 258 THR B CA  1 
ATOM   3142 C C   . THR B 2 88  ? -11.623 6.878   8.093   1   27.27  ? 258 THR B C   1 
ATOM   3143 O O   . THR B 2 88  ? -10.923 5.989   7.633   1   29.29  ? 258 THR B O   1 
ATOM   3144 C CB  . THR B 2 88  ? -10.898 9.282   7.902   1   29.33  ? 258 THR B CB  1 
ATOM   3145 O OG1 . THR B 2 88  ? -11.19  10.454  7.146   1   30.2   ? 258 THR B OG1 1 
ATOM   3146 C CG2 . THR B 2 88  ? -9.413  8.956   7.837   1   30.98  ? 258 THR B CG2 1 
ATOM   3147 N N   . ALA B 2 89  ? -12.274 6.785   9.261   1   27.42  ? 259 ALA B N   1 
ATOM   3148 C CA  . ALA B 2 89  ? -12.206 5.599   10.112  1   27.34  ? 259 ALA B CA  1 
ATOM   3149 C C   . ALA B 2 89  ? -12.909 4.423   9.438   1   26     ? 259 ALA B C   1 
ATOM   3150 O O   . ALA B 2 89  ? -12.521 3.266   9.582   1   24.71  ? 259 ALA B O   1 
ATOM   3151 C CB  . ALA B 2 89  ? -12.826 5.888   11.462  1   26.13  ? 259 ALA B CB  1 
ATOM   3152 N N   . ALA B 2 90  ? -13.978 4.728   8.708   1   24.6   ? 260 ALA B N   1 
ATOM   3153 C CA  . ALA B 2 90  ? -14.696 3.676   8.029   1   24.23  ? 260 ALA B CA  1 
ATOM   3154 C C   . ALA B 2 90  ? -13.791 3.083   6.944   1   29.65  ? 260 ALA B C   1 
ATOM   3155 O O   . ALA B 2 90  ? -13.73  1.858   6.785   1   32.77  ? 260 ALA B O   1 
ATOM   3156 C CB  . ALA B 2 90  ? -15.945 4.273   7.464   1   24.85  ? 260 ALA B CB  1 
ATOM   3157 N N   . MET B 2 91  ? -13.069 3.954   6.212   1   27.13  ? 261 MET B N   1 
ATOM   3158 C CA  . MET B 2 91  ? -12.176 3.535   5.141   1   26.77  ? 261 MET B CA  1 
ATOM   3159 C C   . MET B 2 91  ? -11.017 2.701   5.719   1   27.54  ? 261 MET B C   1 
ATOM   3160 O O   . MET B 2 91  ? -10.636 1.689   5.133   1   26.37  ? 261 MET B O   1 
ATOM   3161 C CB  . MET B 2 91  ? -11.682 4.751   4.348   1   25.93  ? 261 MET B CB  1 
ATOM   3162 C CG  . MET B 2 91  ? -11.187 4.433   2.947   1   30.12  ? 261 MET B CG  1 
ATOM   3163 S SD  . MET B 2 91  ? -12.441 3.655   1.91    1   32.84  ? 261 MET B SD  1 
ATOM   3164 C CE  . MET B 2 91  ? -11.638 3.692   0.307   1   37.5   ? 261 MET B CE  1 
ATOM   3165 N N   . LEU B 2 92  ? -10.488 3.105   6.886   1   23.56  ? 262 LEU B N   1 
ATOM   3166 C CA  . LEU B 2 92  ? -9.447  2.359   7.565   1   24.96  ? 262 LEU B CA  1 
ATOM   3167 C C   . LEU B 2 92  ? -9.948  0.959   7.931   1   27.21  ? 262 LEU B C   1 
ATOM   3168 O O   . LEU B 2 92  ? -9.259  -0.03   7.685   1   30.61  ? 262 LEU B O   1 
ATOM   3169 C CB  . LEU B 2 92  ? -9.008  3.143   8.804   1   24.63  ? 262 LEU B CB  1 
ATOM   3170 C CG  . LEU B 2 92  ? -7.939  2.497   9.696   1   23.46  ? 262 LEU B CG  1 
ATOM   3171 C CD1 . LEU B 2 92  ? -6.587  2.385   9.04    1   21.15  ? 262 LEU B CD1 1 
ATOM   3172 C CD2 . LEU B 2 92  ? -7.789  3.31    10.96   1   22.65  ? 262 LEU B CD2 1 
ATOM   3173 N N   . LEU B 2 93  ? -11.14  0.866   8.52    1   25.23  ? 263 LEU B N   1 
ATOM   3174 C CA  . LEU B 2 93  ? -11.653 -0.415  8.974   1   24.15  ? 263 LEU B CA  1 
ATOM   3175 C C   . LEU B 2 93  ? -11.89  -1.301  7.758   1   24.82  ? 263 LEU B C   1 
ATOM   3176 O O   . LEU B 2 93  ? -11.584 -2.49   7.751   1   24.76  ? 263 LEU B O   1 
ATOM   3177 C CB  . LEU B 2 93  ? -12.948 -0.195  9.765   1   23.27  ? 263 LEU B CB  1 
ATOM   3178 C CG  . LEU B 2 93  ? -12.796 0.292   11.216  1   23.39  ? 263 LEU B CG  1 
ATOM   3179 C CD1 . LEU B 2 93  ? -14.183 0.561   11.823  1   20.18  ? 263 LEU B CD1 1 
ATOM   3180 C CD2 . LEU B 2 93  ? -12.047 -0.741  12.067  1   20.68  ? 263 LEU B CD2 1 
ATOM   3181 N N   . ALA B 2 94  ? -12.464 -0.709  6.718   1   27.39  ? 264 ALA B N   1 
ATOM   3182 C CA  . ALA B 2 94  ? -12.76  -1.47   5.511   1   29.79  ? 264 ALA B CA  1 
ATOM   3183 C C   . ALA B 2 94  ? -11.472 -1.981  4.862   1   25.03  ? 264 ALA B C   1 
ATOM   3184 O O   . ALA B 2 94  ? -11.415 -3.119  4.42    1   23.54  ? 264 ALA B O   1 
ATOM   3185 C CB  . ALA B 2 94  ? -13.552 -0.606  4.559   1   33.05  ? 264 ALA B CB  1 
ATOM   3186 N N   . SER B 2 95  ? -10.456 -1.118  4.787   1   24.31  ? 265 SER B N   1 
ATOM   3187 C CA  . SER B 2 95  ? -9.12   -1.486  4.338   1   25.64  ? 265 SER B CA  1 
ATOM   3188 C C   . SER B 2 95  ? -8.546  -2.64   5.154   1   25.16  ? 265 SER B C   1 
ATOM   3189 O O   . SER B 2 95  ? -8.065  -3.597  4.568   1   29.76  ? 265 SER B O   1 
ATOM   3190 C CB  . SER B 2 95  ? -8.179  -0.314  4.358   1   26.53  ? 265 SER B CB  1 
ATOM   3191 O OG  . SER B 2 95  ? -8.593  0.643   3.393   1   31.09  ? 265 SER B OG  1 
ATOM   3192 N N   . LYS B 2 96  ? -8.592  -2.56   6.491   1   22.21  ? 266 LYS B N   1 
ATOM   3193 C CA  . LYS B 2 96  ? -8.022  -3.626  7.308   1   22.02  ? 266 LYS B CA  1 
ATOM   3194 C C   . LYS B 2 96  ? -8.768  -4.949  7.109   1   21.36  ? 266 LYS B C   1 
ATOM   3195 O O   . LYS B 2 96  ? -8.169  -6.009  7.233   1   20.72  ? 266 LYS B O   1 
ATOM   3196 C CB  . LYS B 2 96  ? -7.969  -3.249  8.79    1   22.47  ? 266 LYS B CB  1 
ATOM   3197 C CG  . LYS B 2 96  ? -6.892  -2.247  9.21    1   21.74  ? 266 LYS B CG  1 
ATOM   3198 C CD  . LYS B 2 96  ? -7.101  -1.825  10.655  1   21.22  ? 266 LYS B CD  1 
ATOM   3199 C CE  . LYS B 2 96  ? -6.127  -0.824  11.196  1   22.6   ? 266 LYS B CE  1 
ATOM   3200 N NZ  . LYS B 2 96  ? -6.335  -0.642  12.642  1   20.25  ? 266 LYS B NZ  1 
ATOM   3201 N N   . PHE B 2 97  ? -10.065 -4.903  6.793   1   20.77  ? 267 PHE B N   1 
ATOM   3202 C CA  . PHE B 2 97  ? -10.815 -6.131  6.585   1   23.43  ? 267 PHE B CA  1 
ATOM   3203 C C   . PHE B 2 97  ? -10.571 -6.72   5.192   1   25.01  ? 267 PHE B C   1 
ATOM   3204 O O   . PHE B 2 97  ? -10.42  -7.936  5.043   1   23.54  ? 267 PHE B O   1 
ATOM   3205 C CB  . PHE B 2 97  ? -12.308 -5.837  6.743   1   25.75  ? 267 PHE B CB  1 
ATOM   3206 C CG  . PHE B 2 97  ? -13.223 -7.043  6.608   1   26.02  ? 267 PHE B CG  1 
ATOM   3207 C CD1 . PHE B 2 97  ? -13.743 -7.405  5.369   1   26.29  ? 267 PHE B CD1 1 
ATOM   3208 C CD2 . PHE B 2 97  ? -13.599 -7.782  7.73    1   27.91  ? 267 PHE B CD2 1 
ATOM   3209 C CE1 . PHE B 2 97  ? -14.62  -8.482  5.248   1   27.67  ? 267 PHE B CE1 1 
ATOM   3210 C CE2 . PHE B 2 97  ? -14.473 -8.864  7.611   1   28.41  ? 267 PHE B CE2 1 
ATOM   3211 C CZ  . PHE B 2 97  ? -14.985 -9.212  6.368   1   29.89  ? 267 PHE B CZ  1 
ATOM   3212 N N   . GLU B 2 98  ? -10.567 -5.869  4.158   1   25.14  ? 268 GLU B N   1 
ATOM   3213 C CA  . GLU B 2 98  ? -10.651 -6.387  2.801   1   25.25  ? 268 GLU B CA  1 
ATOM   3214 C C   . GLU B 2 98  ? -9.295  -6.39   2.089   1   25.03  ? 268 GLU B C   1 
ATOM   3215 O O   . GLU B 2 98  ? -9.116  -7.233  1.218   1   25.07  ? 268 GLU B O   1 
ATOM   3216 C CB  . GLU B 2 98  ? -11.71  -5.649  1.99    1   23.13  ? 268 GLU B CB  1 
ATOM   3217 C CG  . GLU B 2 98  ? -12.061 -6.365  0.686   1   25.1   ? 268 GLU B CG  1 
ATOM   3218 C CD  . GLU B 2 98  ? -12.732 -7.715  0.912   1   28.33  ? 268 GLU B CD  1 
ATOM   3219 O OE1 . GLU B 2 98  ? -13.379 -7.928  1.974   1   28.54  ? 268 GLU B OE1 1 
ATOM   3220 O OE2 . GLU B 2 98  ? -12.622 -8.573  0.009   1   28.23  ? 268 GLU B OE2 1 
ATOM   3221 N N   . GLU B 2 99  ? -8.363  -5.499  2.478   1   22.24  ? 269 GLU B N   1 
ATOM   3222 C CA  . GLU B 2 99  ? -7.11   -5.31   1.753   1   24.25  ? 269 GLU B CA  1 
ATOM   3223 C C   . GLU B 2 99  ? -6.015  -6.255  2.245   1   26.99  ? 269 GLU B C   1 
ATOM   3224 O O   . GLU B 2 99  ? -5.853  -6.474  3.446   1   27.26  ? 269 GLU B O   1 
ATOM   3225 C CB  . GLU B 2 99  ? -6.605  -3.873  1.818   1   23.03  ? 269 GLU B CB  1 
ATOM   3226 C CG  . GLU B 2 99  ? -7.566  -2.907  1.129   1   27.08  ? 269 GLU B CG  1 
ATOM   3227 C CD  . GLU B 2 99  ? -7.588  -2.935  -0.394  1   27.92  ? 269 GLU B CD  1 
ATOM   3228 O OE1 . GLU B 2 99  ? -6.553  -3.321  -0.993  1   31.56  ? 269 GLU B OE1 1 
ATOM   3229 O OE2 . GLU B 2 99  ? -8.642  -2.595  -0.979  1   25.07  ? 269 GLU B OE2 1 
ATOM   3230 N N   . ILE B 2 100 ? -5.272  -6.807  1.275   1   26.06  ? 270 ILE B N   1 
ATOM   3231 C CA  . ILE B 2 100 ? -4.044  -7.531  1.513   1   24.49  ? 270 ILE B CA  1 
ATOM   3232 C C   . ILE B 2 100 ? -3.053  -6.575  2.155   1   25.79  ? 270 ILE B C   1 
ATOM   3233 O O   . ILE B 2 100 ? -2.379  -6.964  3.099   1   29.85  ? 270 ILE B O   1 
ATOM   3234 C CB  . ILE B 2 100 ? -3.468  -8.056  0.185   1   27.84  ? 270 ILE B CB  1 
ATOM   3235 C CG1 . ILE B 2 100 ? -4.453  -8.937  -0.61   1   27.29  ? 270 ILE B CG1 1 
ATOM   3236 C CG2 . ILE B 2 100 ? -2.102  -8.723  0.373   1   24.11  ? 270 ILE B CG2 1 
ATOM   3237 C CD1 . ILE B 2 100 ? -3.821  -9.492  -1.874  1   25.43  ? 270 ILE B CD1 1 
ATOM   3238 N N   . TYR B 2 101 ? -2.937  -5.364  1.593   1   26.01  ? 271 TYR B N   1 
ATOM   3239 C CA  . TYR B 2 101 ? -1.968  -4.361  2.019   1   27.82  ? 271 TYR B CA  1 
ATOM   3240 C C   . TYR B 2 101 ? -2.669  -3.048  2.366   1   28.44  ? 271 TYR B C   1 
ATOM   3241 O O   . TYR B 2 101 ? -2.661  -2.106  1.573   1   31.09  ? 271 TYR B O   1 
ATOM   3242 C CB  . TYR B 2 101 ? -0.896  -4.155  0.942   1   28.48  ? 271 TYR B CB  1 
ATOM   3243 C CG  . TYR B 2 101 ? 0.004   -5.368  0.782   1   31.43  ? 271 TYR B CG  1 
ATOM   3244 C CD1 . TYR B 2 101 ? 0.791   -5.805  1.85    1   33.27  ? 271 TYR B CD1 1 
ATOM   3245 C CD2 . TYR B 2 101 ? 0.085   -6.061  -0.429  1   34.48  ? 271 TYR B CD2 1 
ATOM   3246 C CE1 . TYR B 2 101 ? 1.629   -6.906  1.727   1   33.09  ? 271 TYR B CE1 1 
ATOM   3247 C CE2 . TYR B 2 101 ? 0.921   -7.164  -0.562  1   33.69  ? 271 TYR B CE2 1 
ATOM   3248 C CZ  . TYR B 2 101 ? 1.675   -7.592  0.521   1   32.95  ? 271 TYR B CZ  1 
ATOM   3249 O OH  . TYR B 2 101 ? 2.488   -8.673  0.401   1   37.06  ? 271 TYR B OH  1 
ATOM   3250 N N   . PRO B 2 102 ? -3.302  -2.937  3.559   1   27.4   ? 272 PRO B N   1 
ATOM   3251 C CA  . PRO B 2 102 ? -4.005  -1.706  3.936   1   27.08  ? 272 PRO B CA  1 
ATOM   3252 C C   . PRO B 2 102 ? -3.027  -0.55   4.081   1   27.81  ? 272 PRO B C   1 
ATOM   3253 O O   . PRO B 2 102 ? -1.892  -0.72   4.536   1   29.83  ? 272 PRO B O   1 
ATOM   3254 C CB  . PRO B 2 102 ? -4.674  -2.051  5.277   1   28.97  ? 272 PRO B CB  1 
ATOM   3255 C CG  . PRO B 2 102 ? -3.824  -3.201  5.814   1   27.74  ? 272 PRO B CG  1 
ATOM   3256 C CD  . PRO B 2 102 ? -3.378  -3.985  4.592   1   24.65  ? 272 PRO B CD  1 
ATOM   3257 N N   . PRO B 2 103 ? -3.421  0.674   3.686   1   27.74  ? 273 PRO B N   1 
ATOM   3258 C CA  . PRO B 2 103 ? -2.574  1.841   3.928   1   28.37  ? 273 PRO B CA  1 
ATOM   3259 C C   . PRO B 2 103 ? -2.428  2.029   5.435   1   29.11  ? 273 PRO B C   1 
ATOM   3260 O O   . PRO B 2 103 ? -3.341  1.753   6.204   1   30.64  ? 273 PRO B O   1 
ATOM   3261 C CB  . PRO B 2 103 ? -3.363  2.992   3.275   1   26.37  ? 273 PRO B CB  1 
ATOM   3262 C CG  . PRO B 2 103 ? -4.299  2.326   2.308   1   23.2   ? 273 PRO B CG  1 
ATOM   3263 C CD  . PRO B 2 103 ? -4.656  0.996   2.957   1   25.95  ? 273 PRO B CD  1 
ATOM   3264 N N   . GLU B 2 104 ? -1.269  2.506   5.856   1   30.52  ? 274 GLU B N   1 
ATOM   3265 C CA  . GLU B 2 104 ? -1.037  2.797   7.26    1   35.63  ? 274 GLU B CA  1 
ATOM   3266 C C   . GLU B 2 104 ? -1.957  3.922   7.748   1   37.06  ? 274 GLU B C   1 
ATOM   3267 O O   . GLU B 2 104 ? -2.436  4.769   6.985   1   35.99  ? 274 GLU B O   1 
ATOM   3268 C CB  . GLU B 2 104 ? 0.42    3.233   7.41    1   40.89  ? 274 GLU B CB  1 
ATOM   3269 C CG  . GLU B 2 104 ? 1.418   2.099   7.197   1   48.95  ? 274 GLU B CG  1 
ATOM   3270 C CD  . GLU B 2 104 ? 2.822   2.558   6.855   1   59.65  ? 274 GLU B CD  1 
ATOM   3271 O OE1 . GLU B 2 104 ? 3.653   1.64    6.678   1   63.95  ? 274 GLU B OE1 1 
ATOM   3272 O OE2 . GLU B 2 104 ? 3.09    3.788   6.758   1   66.65  ? 274 GLU B OE2 1 
ATOM   3273 N N   . VAL B 2 105 ? -2.171  3.945   9.062   1   36.52  ? 275 VAL B N   1 
ATOM   3274 C CA  . VAL B 2 105 ? -2.971  4.994   9.681   1   36.27  ? 275 VAL B CA  1 
ATOM   3275 C C   . VAL B 2 105 ? -2.484  6.376   9.237   1   33.9   ? 275 VAL B C   1 
ATOM   3276 O O   . VAL B 2 105 ? -3.296  7.241   8.902   1   34.37  ? 275 VAL B O   1 
ATOM   3277 C CB  . VAL B 2 105 ? -3.001  4.841   11.215  1   33.13  ? 275 VAL B CB  1 
ATOM   3278 C CG1 . VAL B 2 105 ? -3.559  6.07    11.917  1   30.3   ? 275 VAL B CG1 1 
ATOM   3279 C CG2 . VAL B 2 105 ? -3.801  3.608   11.597  1   32.3   ? 275 VAL B CG2 1 
ATOM   3280 N N   . ALA B 2 106 ? -1.161  6.565   9.211   1   28.02  ? 276 ALA B N   1 
ATOM   3281 C CA  . ALA B 2 106 ? -0.599  7.863   8.894   1   27.1   ? 276 ALA B CA  1 
ATOM   3282 C C   . ALA B 2 106 ? -1.053  8.318   7.503   1   28.04  ? 276 ALA B C   1 
ATOM   3283 O O   . ALA B 2 106 ? -1.197  9.518   7.284   1   30.47  ? 276 ALA B O   1 
ATOM   3284 C CB  . ALA B 2 106 ? 0.906   7.865   9.069   1   24.17  ? 276 ALA B CB  1 
ATOM   3285 N N   . GLU B 2 107 ? -1.305  7.375   6.582   1   25     ? 277 GLU B N   1 
ATOM   3286 C CA  . GLU B 2 107 ? -1.695  7.771   5.244   1   29.38  ? 277 GLU B CA  1 
ATOM   3287 C C   . GLU B 2 107 ? -3.144  8.244   5.254   1   31.14  ? 277 GLU B C   1 
ATOM   3288 O O   . GLU B 2 107 ? -3.515  9.168   4.533   1   34.24  ? 277 GLU B O   1 
ATOM   3289 C CB  . GLU B 2 107 ? -1.448  6.653   4.237   1   35.73  ? 277 GLU B CB  1 
ATOM   3290 C CG  . GLU B 2 107 ? 0.01    6.577   3.794   1   46.77  ? 277 GLU B CG  1 
ATOM   3291 C CD  . GLU B 2 107 ? 0.369   5.253   3.132   1   62.8   ? 277 GLU B CD  1 
ATOM   3292 O OE1 . GLU B 2 107 ? 0.788   5.318   1.952   1   73.33  ? 277 GLU B OE1 1 
ATOM   3293 O OE2 . GLU B 2 107 ? 0.221   4.167   3.762   1   58.87  ? 277 GLU B OE2 1 
ATOM   3294 N N   . PHE B 2 108 ? -3.969  7.601   6.073   1   30.21  ? 278 PHE B N   1 
ATOM   3295 C CA  . PHE B 2 108 ? -5.321  8.091   6.314   1   29.97  ? 278 PHE B CA  1 
ATOM   3296 C C   . PHE B 2 108 ? -5.293  9.489   6.949   1   31.8   ? 278 PHE B C   1 
ATOM   3297 O O   . PHE B 2 108 ? -6.079  10.344  6.56    1   37.05  ? 278 PHE B O   1 
ATOM   3298 C CB  . PHE B 2 108 ? -6.145  7.046   7.073   1   25.29  ? 278 PHE B CB  1 
ATOM   3299 C CG  . PHE B 2 108 ? -6.532  5.863   6.202   1   26.38  ? 278 PHE B CG  1 
ATOM   3300 C CD1 . PHE B 2 108 ? -7.547  5.981   5.261   1   25.05  ? 278 PHE B CD1 1 
ATOM   3301 C CD2 . PHE B 2 108 ? -5.896  4.631   6.331   1   26.13  ? 278 PHE B CD2 1 
ATOM   3302 C CE1 . PHE B 2 108 ? -7.893  4.893   4.477   1   24.75  ? 278 PHE B CE1 1 
ATOM   3303 C CE2 . PHE B 2 108 ? -6.252  3.553   5.532   1   24.74  ? 278 PHE B CE2 1 
ATOM   3304 C CZ  . PHE B 2 108 ? -7.245  3.683   4.604   1   24.22  ? 278 PHE B CZ  1 
ATOM   3305 N N   . VAL B 2 109 ? -4.399  9.733   7.919   1   30.11  ? 279 VAL B N   1 
ATOM   3306 C CA  . VAL B 2 109 ? -4.287  11.047  8.527   1   30.66  ? 279 VAL B CA  1 
ATOM   3307 C C   . VAL B 2 109 ? -3.852  12.046  7.46    1   32.49  ? 279 VAL B C   1 
ATOM   3308 O O   . VAL B 2 109 ? -4.301  13.189  7.462   1   35.14  ? 279 VAL B O   1 
ATOM   3309 C CB  . VAL B 2 109 ? -3.328  11.081  9.737   1   29.34  ? 279 VAL B CB  1 
ATOM   3310 C CG1 . VAL B 2 109 ? -3.096  12.502  10.252  1   25.39  ? 279 VAL B CG1 1 
ATOM   3311 C CG2 . VAL B 2 109 ? -3.764  10.159  10.87   1   26.66  ? 279 VAL B CG2 1 
ATOM   3312 N N   . TYR B 2 110 ? -2.984  11.596  6.554   1   34.56  ? 280 TYR B N   1 
ATOM   3313 C CA  . TYR B 2 110 ? -2.419  12.463  5.534   1   40.77  ? 280 TYR B CA  1 
ATOM   3314 C C   . TYR B 2 110 ? -3.516  12.985  4.595   1   45.04  ? 280 TYR B C   1 
ATOM   3315 O O   . TYR B 2 110 ? -3.552  14.185  4.313   1   52.41  ? 280 TYR B O   1 
ATOM   3316 C CB  . TYR B 2 110 ? -1.27   11.764  4.796   1   41.42  ? 280 TYR B CB  1 
ATOM   3317 C CG  . TYR B 2 110 ? -0.662  12.585  3.666   1   45.31  ? 280 TYR B CG  1 
ATOM   3318 C CD1 . TYR B 2 110 ? -0.087  13.835  3.906   1   48.29  ? 280 TYR B CD1 1 
ATOM   3319 C CD2 . TYR B 2 110 ? -0.708  12.129  2.345   1   45.57  ? 280 TYR B CD2 1 
ATOM   3320 C CE1 . TYR B 2 110 ? 0.454   14.589  2.873   1   47.35  ? 280 TYR B CE1 1 
ATOM   3321 C CE2 . TYR B 2 110 ? -0.174  12.874  1.305   1   45.22  ? 280 TYR B CE2 1 
ATOM   3322 C CZ  . TYR B 2 110 ? 0.415   14.103  1.573   1   49.3   ? 280 TYR B CZ  1 
ATOM   3323 O OH  . TYR B 2 110 ? 0.945   14.842  0.55    1   52.11  ? 280 TYR B OH  1 
ATOM   3324 N N   . ILE B 2 111 ? -4.411  12.103  4.116   1   42.78  ? 281 ILE B N   1 
ATOM   3325 C CA  . ILE B 2 111 ? -5.351  12.47   3.062   1   41.53  ? 281 ILE B CA  1 
ATOM   3326 C C   . ILE B 2 111 ? -6.438  13.407  3.575   1   41.41  ? 281 ILE B C   1 
ATOM   3327 O O   . ILE B 2 111 ? -7.124  14.033  2.776   1   44.89  ? 281 ILE B O   1 
ATOM   3328 C CB  . ILE B 2 111 ? -5.99   11.26   2.365   1   41.53  ? 281 ILE B CB  1 
ATOM   3329 C CG1 . ILE B 2 111 ? -6.377  10.184  3.374   1   39.43  ? 281 ILE B CG1 1 
ATOM   3330 C CG2 . ILE B 2 111 ? -5.074  10.747  1.254   1   41.36  ? 281 ILE B CG2 1 
ATOM   3331 C CD1 . ILE B 2 111 ? -7.714  9.511   3.101   1   48.03  ? 281 ILE B CD1 1 
ATOM   3332 N N   . THR B 2 112 ? -6.608  13.485  4.895   1   39.6   ? 282 THR B N   1 
ATOM   3333 C CA  . THR B 2 112 ? -7.556  14.422  5.476   1   41.48  ? 282 THR B CA  1 
ATOM   3334 C C   . THR B 2 112 ? -6.927  15.799  5.677   1   47.08  ? 282 THR B C   1 
ATOM   3335 O O   . THR B 2 112 ? -7.504  16.597  6.415   1   48.47  ? 282 THR B O   1 
ATOM   3336 C CB  . THR B 2 112 ? -8.095  13.894  6.804   1   43.08  ? 282 THR B CB  1 
ATOM   3337 O OG1 . THR B 2 112 ? -6.96   13.755  7.656   1   45.77  ? 282 THR B OG1 1 
ATOM   3338 C CG2 . THR B 2 112 ? -8.853  12.588  6.661   1   38.53  ? 282 THR B CG2 1 
ATOM   3339 N N   . ASP B 2 113 ? -5.754  16.05   5.061   1   55.28  ? 283 ASP B N   1 
ATOM   3340 C CA  . ASP B 2 113 ? -5.054  17.333  5.062   1   59.88  ? 283 ASP B CA  1 
ATOM   3341 C C   . ASP B 2 113 ? -4.788  17.835  6.476   1   61.71  ? 283 ASP B C   1 
ATOM   3342 O O   . ASP B 2 113 ? -4.875  19.037  6.725   1   62.86  ? 283 ASP B O   1 
ATOM   3343 C CB  . ASP B 2 113 ? -5.805  18.381  4.258   1   65.82  ? 283 ASP B CB  1 
ATOM   3344 C CG  . ASP B 2 113 ? -5.72   18.18   2.754   1   79.98  ? 283 ASP B CG  1 
ATOM   3345 O OD1 . ASP B 2 113 ? -4.58   18.156  2.247   1   85.73  ? 283 ASP B OD1 1 
ATOM   3346 O OD2 . ASP B 2 113 ? -6.785  18.042  2.108   1   83.91  ? 283 ASP B OD2 1 
ATOM   3347 N N   . ASP B 2 114 ? -4.455  16.9    7.378   1   64.68  ? 284 ASP B N   1 
ATOM   3348 C CA  . ASP B 2 114 ? -4.244  17.148  8.8     1   68.23  ? 284 ASP B CA  1 
ATOM   3349 C C   . ASP B 2 114 ? -5.39   17.969  9.406   1   57.73  ? 284 ASP B C   1 
ATOM   3350 O O   . ASP B 2 114 ? -5.17   18.797  10.289  1   49.18  ? 284 ASP B O   1 
ATOM   3351 C CB  . ASP B 2 114 ? -2.852  17.705  9.066   1   78.92  ? 284 ASP B CB  1 
ATOM   3352 C CG  . ASP B 2 114 ? -1.69   17.028  8.344   1   79.56  ? 284 ASP B CG  1 
ATOM   3353 O OD1 . ASP B 2 114 ? -1.421  15.841  8.616   1   76.44  ? 284 ASP B OD1 1 
ATOM   3354 O OD2 . ASP B 2 114 ? -1.04   17.703  7.52    1   81.26  ? 284 ASP B OD2 1 
ATOM   3355 N N   . THR B 2 115 ? -6.624  17.721  8.941   1   54.51  ? 285 THR B N   1 
ATOM   3356 C CA  . THR B 2 115 ? -7.822  18.202  9.618   1   51.73  ? 285 THR B CA  1 
ATOM   3357 C C   . THR B 2 115 ? -7.878  17.53   10.99   1   46.53  ? 285 THR B C   1 
ATOM   3358 O O   . THR B 2 115 ? -8.149  18.194  11.986  1   52.24  ? 285 THR B O   1 
ATOM   3359 C CB  . THR B 2 115 ? -9.088  17.919  8.796   1   50.65  ? 285 THR B CB  1 
ATOM   3360 O OG1 . THR B 2 115 ? -8.886  18.359  7.461   1   46.77  ? 285 THR B OG1 1 
ATOM   3361 C CG2 . THR B 2 115 ? -10.322 18.64   9.313   1   48.03  ? 285 THR B CG2 1 
ATOM   3362 N N   . TYR B 2 116 ? -7.564  16.226  11.023  1   37.66  ? 286 TYR B N   1 
ATOM   3363 C CA  . TYR B 2 116 ? -7.655  15.404  12.218  1   33.65  ? 286 TYR B CA  1 
ATOM   3364 C C   . TYR B 2 116 ? -6.285  14.854  12.578  1   33.43  ? 286 TYR B C   1 
ATOM   3365 O O   . TYR B 2 116 ? -5.374  14.901  11.757  1   36.96  ? 286 TYR B O   1 
ATOM   3366 C CB  . TYR B 2 116 ? -8.568  14.205  11.95   1   30.72  ? 286 TYR B CB  1 
ATOM   3367 C CG  . TYR B 2 116 ? -9.91   14.641  11.39   1   31.42  ? 286 TYR B CG  1 
ATOM   3368 C CD1 . TYR B 2 116 ? -10.818 15.334  12.181  1   30.44  ? 286 TYR B CD1 1 
ATOM   3369 C CD2 . TYR B 2 116 ? -10.257 14.384  10.071  1   29.62  ? 286 TYR B CD2 1 
ATOM   3370 C CE1 . TYR B 2 116 ? -12.032 15.752  11.67   1   28.88  ? 286 TYR B CE1 1 
ATOM   3371 C CE2 . TYR B 2 116 ? -11.465 14.813  9.554   1   27.54  ? 286 TYR B CE2 1 
ATOM   3372 C CZ  . TYR B 2 116 ? -12.357 15.493  10.357  1   25.95  ? 286 TYR B CZ  1 
ATOM   3373 O OH  . TYR B 2 116 ? -13.567 15.903  9.897   1   28.33  ? 286 TYR B OH  1 
ATOM   3374 N N   . THR B 2 117 ? -6.175  14.325  13.803  1   32.45  ? 287 THR B N   1 
ATOM   3375 C CA  . THR B 2 117 ? -4.941  13.752  14.316  1   31.35  ? 287 THR B CA  1 
ATOM   3376 C C   . THR B 2 117 ? -4.986  12.229  14.23   1   30.8   ? 287 THR B C   1 
ATOM   3377 O O   . THR B 2 117 ? -6.044  11.623  14.214  1   32.15  ? 287 THR B O   1 
ATOM   3378 C CB  . THR B 2 117 ? -4.696  14.176  15.764  1   32.18  ? 287 THR B CB  1 
ATOM   3379 O OG1 . THR B 2 117 ? -5.843  13.774  16.511  1   32.93  ? 287 THR B OG1 1 
ATOM   3380 C CG2 . THR B 2 117 ? -4.397  15.656  15.908  1   28.39  ? 287 THR B CG2 1 
ATOM   3381 N N   . LYS B 2 118 ? -3.809  11.61   14.226  1   32.72  ? 288 LYS B N   1 
ATOM   3382 C CA  . LYS B 2 118 ? -3.69   10.169  14.342  1   32.85  ? 288 LYS B CA  1 
ATOM   3383 C C   . LYS B 2 118 ? -4.61   9.678   15.455  1   29.56  ? 288 LYS B C   1 
ATOM   3384 O O   . LYS B 2 118 ? -5.336  8.722   15.26   1   30.54  ? 288 LYS B O   1 
ATOM   3385 C CB  . LYS B 2 118 ? -2.233  9.765   14.593  1   36.95  ? 288 LYS B CB  1 
ATOM   3386 C CG  . LYS B 2 118 ? -1.872  8.348   14.168  1   41.65  ? 288 LYS B CG  1 
ATOM   3387 C CD  . LYS B 2 118 ? -0.685  7.763   14.922  1   52.37  ? 288 LYS B CD  1 
ATOM   3388 C CE  . LYS B 2 118 ? -0.379  6.325   14.627  1   56.71  ? 288 LYS B CE  1 
ATOM   3389 N NZ  . LYS B 2 118 ? 0.557   5.806   15.632  1   60.72  ? 288 LYS B NZ  1 
ATOM   3390 N N   . LYS B 2 119 ? -4.612  10.353  16.605  1   31.56  ? 289 LYS B N   1 
ATOM   3391 C CA  . LYS B 2 119 ? -5.365  9.905   17.772  1   32.79  ? 289 LYS B CA  1 
ATOM   3392 C C   . LYS B 2 119 ? -6.868  10.03   17.536  1   29.52  ? 289 LYS B C   1 
ATOM   3393 O O   . LYS B 2 119 ? -7.643  9.189   17.979  1   27.8   ? 289 LYS B O   1 
ATOM   3394 C CB  . LYS B 2 119 ? -5.005  10.756  18.994  1   38.84  ? 289 LYS B CB  1 
ATOM   3395 C CG  . LYS B 2 119 ? -5.183  10.054  20.33   1   47.74  ? 289 LYS B CG  1 
ATOM   3396 C CD  . LYS B 2 119 ? -4.485  10.743  21.499  1   52.88  ? 289 LYS B CD  1 
ATOM   3397 C CE  . LYS B 2 119 ? -5.208  11.973  21.973  1   60.38  ? 289 LYS B CE  1 
ATOM   3398 N NZ  . LYS B 2 119 ? -6.494  11.648  22.603  1   64.26  ? 289 LYS B NZ  1 
ATOM   3399 N N   . GLN B 2 120 ? -7.275  11.088  16.834  1   28.17  ? 290 GLN B N   1 
ATOM   3400 C CA  . GLN B 2 120 ? -8.666  11.252  16.455  1   28.75  ? 290 GLN B CA  1 
ATOM   3401 C C   . GLN B 2 120 ? -9.151  10.139  15.526  1   28.16  ? 290 GLN B C   1 
ATOM   3402 O O   . GLN B 2 120 ? -10.237 9.608   15.722  1   32.13  ? 290 GLN B O   1 
ATOM   3403 C CB  . GLN B 2 120 ? -8.874  12.622  15.837  1   29.53  ? 290 GLN B CB  1 
ATOM   3404 C CG  . GLN B 2 120 ? -8.896  13.752  16.856  1   31.82  ? 290 GLN B CG  1 
ATOM   3405 C CD  . GLN B 2 120 ? -9.273  15.043  16.172  1   34.46  ? 290 GLN B CD  1 
ATOM   3406 O OE1 . GLN B 2 120 ? -8.595  15.488  15.232  1   32.57  ? 290 GLN B OE1 1 
ATOM   3407 N NE2 . GLN B 2 120 ? -10.426 15.576  16.565  1   33.63  ? 290 GLN B NE2 1 
ATOM   3408 N N   . VAL B 2 121 ? -8.363  9.786   14.515  1   25.9   ? 291 VAL B N   1 
ATOM   3409 C CA  . VAL B 2 121 ? -8.728  8.693   13.633  1   26.62  ? 291 VAL B CA  1 
ATOM   3410 C C   . VAL B 2 121 ? -8.852  7.394   14.433  1   26.6   ? 291 VAL B C   1 
ATOM   3411 O O   . VAL B 2 121 ? -9.809  6.641   14.246  1   29.92  ? 291 VAL B O   1 
ATOM   3412 C CB  . VAL B 2 121 ? -7.74   8.547   12.459  1   26.38  ? 291 VAL B CB  1 
ATOM   3413 C CG1 . VAL B 2 121 ? -7.99   7.278   11.648  1   25.07  ? 291 VAL B CG1 1 
ATOM   3414 C CG2 . VAL B 2 121 ? -7.778  9.759   11.544  1   26.32  ? 291 VAL B CG2 1 
ATOM   3415 N N   . LEU B 2 122 ? -7.872  7.123   15.297  1   26.31  ? 292 LEU B N   1 
ATOM   3416 C CA  . LEU B 2 122 ? -7.834  5.875   16.049  1   27.79  ? 292 LEU B CA  1 
ATOM   3417 C C   . LEU B 2 122 ? -9.015  5.806   17.014  1   27.55  ? 292 LEU B C   1 
ATOM   3418 O O   . LEU B 2 122 ? -9.598  4.742   17.154  1   26.65  ? 292 LEU B O   1 
ATOM   3419 C CB  . LEU B 2 122 ? -6.517  5.657   16.801  1   27.18  ? 292 LEU B CB  1 
ATOM   3420 C CG  . LEU B 2 122 ? -5.255  5.473   15.945  1   28.1   ? 292 LEU B CG  1 
ATOM   3421 C CD1 . LEU B 2 122 ? -4.088  4.98    16.79   1   23.67  ? 292 LEU B CD1 1 
ATOM   3422 C CD2 . LEU B 2 122 ? -5.507  4.588   14.726  1   25.82  ? 292 LEU B CD2 1 
ATOM   3423 N N   . ARG B 2 123 ? -9.33   6.92    17.695  1   27.22  ? 293 ARG B N   1 
ATOM   3424 C CA  . ARG B 2 123 ? -10.447 6.949   18.632  1   29.01  ? 293 ARG B CA  1 
ATOM   3425 C C   . ARG B 2 123 ? -11.756 6.752   17.867  1   27.13  ? 293 ARG B C   1 
ATOM   3426 O O   . ARG B 2 123 ? -12.669 6.098   18.354  1   28.78  ? 293 ARG B O   1 
ATOM   3427 C CB  . ARG B 2 123 ? -10.476 8.194   19.528  1   30.61  ? 293 ARG B CB  1 
ATOM   3428 C CG  . ARG B 2 123 ? -9.4    8.227   20.6    1   35.5   ? 293 ARG B CG  1 
ATOM   3429 C CD  . ARG B 2 123 ? -9.678  9.349   21.59   1   46.96  ? 293 ARG B CD  1 
ATOM   3430 N NE  . ARG B 2 123 ? -9.545  8.878   22.973  1   54.92  ? 293 ARG B NE  1 
ATOM   3431 C CZ  . ARG B 2 123 ? -10.313 7.972   23.589  1   63.07  ? 293 ARG B CZ  1 
ATOM   3432 N NH1 . ARG B 2 123 ? -11.372 7.444   22.986  1   58.12  ? 293 ARG B NH1 1 
ATOM   3433 N NH2 . ARG B 2 123 ? -10.028 7.614   24.836  1   66.94  ? 293 ARG B NH2 1 
ATOM   3434 N N   . MET B 2 124 ? -11.836 7.302   16.658  1   25.92  ? 294 MET B N   1 
ATOM   3435 C CA  . MET B 2 124 ? -13.018 7.118   15.843  1   26.62  ? 294 MET B CA  1 
ATOM   3436 C C   . MET B 2 124 ? -13.082 5.682   15.348  1   27.81  ? 294 MET B C   1 
ATOM   3437 O O   . MET B 2 124 ? -14.179 5.162   15.212  1   31.63  ? 294 MET B O   1 
ATOM   3438 C CB  . MET B 2 124 ? -13.042 8.051   14.631  1   28.58  ? 294 MET B CB  1 
ATOM   3439 C CG  . MET B 2 124 ? -14.298 7.915   13.777  1   26.9   ? 294 MET B CG  1 
ATOM   3440 S SD  . MET B 2 124 ? -15.827 8.393   14.608  1   29.18  ? 294 MET B SD  1 
ATOM   3441 C CE  . MET B 2 124 ? -15.773 10.184  14.758  1   23.68  ? 294 MET B CE  1 
ATOM   3442 N N   . GLU B 2 125 ? -11.947 5.045   15.089  1   26.27  ? 295 GLU B N   1 
ATOM   3443 C CA  . GLU B 2 125 ? -11.968 3.625   14.661  1   26.57  ? 295 GLU B CA  1 
ATOM   3444 C C   . GLU B 2 125 ? -12.676 2.792   15.735  1   28.29  ? 295 GLU B C   1 
ATOM   3445 O O   . GLU B 2 125 ? -13.532 1.965   15.376  1   27.23  ? 295 GLU B O   1 
ATOM   3446 C CB  . GLU B 2 125 ? -10.558 3.12    14.361  1   26.44  ? 295 GLU B CB  1 
ATOM   3447 C CG  . GLU B 2 125 ? -10.441 1.6     14.333  1   26.67  ? 295 GLU B CG  1 
ATOM   3448 C CD  . GLU B 2 125 ? -9.06   1.075   13.995  1   28.98  ? 295 GLU B CD  1 
ATOM   3449 O OE1 . GLU B 2 125 ? -8.197  1.077   14.889  1   32.62  ? 295 GLU B OE1 1 
ATOM   3450 O OE2 . GLU B 2 125 ? -8.845  0.66    12.843  1   30.84  ? 295 GLU B OE2 1 
ATOM   3451 N N   . HIS B 2 126 ? -12.355 3.043   16.999  1   29.09  ? 296 HIS B N   1 
ATOM   3452 C CA  . HIS B 2 126 ? -12.936 2.242   18.102  1   32.46  ? 296 HIS B CA  1 
ATOM   3453 C C   . HIS B 2 126 ? -14.428 2.543   18.23   1   31.03  ? 296 HIS B C   1 
ATOM   3454 O O   . HIS B 2 126 ? -15.199 1.624   18.524  1   31.69  ? 296 HIS B O   1 
ATOM   3455 C CB  . HIS B 2 126 ? -12.161 2.479   19.4    1   37.06  ? 296 HIS B CB  1 
ATOM   3456 C CG  . HIS B 2 126 ? -12.051 1.251   20.23   1   56.82  ? 296 HIS B CG  1 
ATOM   3457 N ND1 . HIS B 2 126 ? -10.982 0.988   21.056  1   68.43  ? 296 HIS B ND1 1 
ATOM   3458 C CD2 . HIS B 2 126 ? -12.879 0.208   20.348  1   67.77  ? 296 HIS B CD2 1 
ATOM   3459 C CE1 . HIS B 2 126 ? -11.174 -0.178  21.652  1   76.24  ? 296 HIS B CE1 1 
ATOM   3460 N NE2 . HIS B 2 126 ? -12.318 -0.669  21.233  1   77.69  ? 296 HIS B NE2 1 
ATOM   3461 N N   . LEU B 2 127 ? -14.816 3.793   17.995  1   25.88  ? 297 LEU B N   1 
ATOM   3462 C CA  . LEU B 2 127 ? -16.24  4.175   18.137  1   25.6   ? 297 LEU B CA  1 
ATOM   3463 C C   . LEU B 2 127 ? -17.057 3.447   17.066  1   23.95  ? 297 LEU B C   1 
ATOM   3464 O O   . LEU B 2 127 ? -18.082 2.86    17.403  1   21.94  ? 297 LEU B O   1 
ATOM   3465 C CB  . LEU B 2 127 ? -16.415 5.69    18.065  1   25.36  ? 297 LEU B CB  1 
ATOM   3466 C CG  . LEU B 2 127 ? -17.823 6.216   18.354  1   23.26  ? 297 LEU B CG  1 
ATOM   3467 C CD1 . LEU B 2 127 ? -18.343 5.657   19.663  1   19.19  ? 297 LEU B CD1 1 
ATOM   3468 C CD2 . LEU B 2 127 ? -17.848 7.73    18.371  1   20.41  ? 297 LEU B CD2 1 
ATOM   3469 N N   . VAL B 2 128 ? -16.589 3.483   15.827  1   23.94  ? 298 VAL B N   1 
ATOM   3470 C CA  . VAL B 2 128 ? -17.295 2.75    14.743  1   25.63  ? 298 VAL B CA  1 
ATOM   3471 C C   . VAL B 2 128 ? -17.331 1.263   15.132  1   30.02  ? 298 VAL B C   1 
ATOM   3472 O O   . VAL B 2 128 ? -18.405 0.66    15.023  1   31.04  ? 298 VAL B O   1 
ATOM   3473 C CB  . VAL B 2 128 ? -16.674 2.997   13.359  1   25.97  ? 298 VAL B CB  1 
ATOM   3474 C CG1 . VAL B 2 128 ? -17.48  2.338   12.251  1   25.49  ? 298 VAL B CG1 1 
ATOM   3475 C CG2 . VAL B 2 128 ? -16.518 4.484   13.076  1   28.32  ? 298 VAL B CG2 1 
ATOM   3476 N N   . LEU B 2 129 ? -16.216 0.714   15.613  1   32.02  ? 299 LEU B N   1 
ATOM   3477 C CA  . LEU B 2 129 ? -16.231 -0.73   15.936  1   30.14  ? 299 LEU B CA  1 
ATOM   3478 C C   . LEU B 2 129 ? -17.281 -0.988  17.019  1   28.85  ? 299 LEU B C   1 
ATOM   3479 O O   . LEU B 2 129 ? -17.982 -1.998  16.935  1   31.06  ? 299 LEU B O   1 
ATOM   3480 C CB  . LEU B 2 129 ? -14.839 -1.191  16.355  1   28.11  ? 299 LEU B CB  1 
ATOM   3481 C CG  . LEU B 2 129 ? -13.866 -1.486  15.213  1   27.43  ? 299 LEU B CG  1 
ATOM   3482 C CD1 . LEU B 2 129 ? -12.504 -1.855  15.759  1   22.39  ? 299 LEU B CD1 1 
ATOM   3483 C CD2 . LEU B 2 129 ? -14.428 -2.592  14.346  1   23.76  ? 299 LEU B CD2 1 
ATOM   3484 N N   . LYS B 2 130 ? -17.385 -0.087  17.982  1   28.82  ? 300 LYS B N   1 
ATOM   3485 C CA  . LYS B 2 130 ? -18.345 -0.268  19.095  1   29.37  ? 300 LYS B CA  1 
ATOM   3486 C C   . LYS B 2 130 ? -19.772 -0.081  18.575  1   29.9   ? 300 LYS B C   1 
ATOM   3487 O O   . LYS B 2 130 ? -20.634 -0.898  18.919  1   31.98  ? 300 LYS B O   1 
ATOM   3488 C CB  . LYS B 2 130 ? -18.025 0.717   20.222  1   29.47  ? 300 LYS B CB  1 
ATOM   3489 C CG  . LYS B 2 130 ? -18.888 0.6     21.469  1   28.1   ? 300 LYS B CG  1 
ATOM   3490 C CD  . LYS B 2 130 ? -18.533 1.6     22.563  1   25.54  ? 300 LYS B CD  1 
ATOM   3491 C CE  . LYS B 2 130 ? -18.856 3.009   22.178  1   23.56  ? 300 LYS B CE  1 
ATOM   3492 N NZ  . LYS B 2 130 ? -20.298 3.212   22.011  1   21.41  ? 300 LYS B NZ  1 
ATOM   3493 N N   . VAL B 2 131 ? -20.001 0.964   17.788  1   28.45  ? 301 VAL B N   1 
ATOM   3494 C CA  . VAL B 2 131 ? -21.333 1.206   17.264  1   26.2   ? 301 VAL B CA  1 
ATOM   3495 C C   . VAL B 2 131 ? -21.792 0.01    16.424  1   26.91  ? 301 VAL B C   1 
ATOM   3496 O O   . VAL B 2 131 ? -22.895 -0.47   16.632  1   29.37  ? 301 VAL B O   1 
ATOM   3497 C CB  . VAL B 2 131 ? -21.428 2.571   16.547  1   25.81  ? 301 VAL B CB  1 
ATOM   3498 C CG1 . VAL B 2 131 ? -22.665 2.716   15.649  1   22.66  ? 301 VAL B CG1 1 
ATOM   3499 C CG2 . VAL B 2 131 ? -21.297 3.734   17.539  1   21.22  ? 301 VAL B CG2 1 
ATOM   3500 N N   . LEU B 2 132 ? -20.941 -0.493  15.517  1   27.65  ? 302 LEU B N   1 
ATOM   3501 C CA  . LEU B 2 132 ? -21.293 -1.56   14.591  1   25.83  ? 302 LEU B CA  1 
ATOM   3502 C C   . LEU B 2 132 ? -21.241 -2.914  15.291  1   28.52  ? 302 LEU B C   1 
ATOM   3503 O O   . LEU B 2 132 ? -21.696 -3.923  14.726  1   25.84  ? 302 LEU B O   1 
ATOM   3504 C CB  . LEU B 2 132 ? -20.329 -1.536  13.41   1   23.08  ? 302 LEU B CB  1 
ATOM   3505 C CG  . LEU B 2 132 ? -20.403 -0.302  12.52   1   23.71  ? 302 LEU B CG  1 
ATOM   3506 C CD1 . LEU B 2 132 ? -19.523 -0.463  11.267  1   26.01  ? 302 LEU B CD1 1 
ATOM   3507 C CD2 . LEU B 2 132 ? -21.826 0.023   12.117  1   23.32  ? 302 LEU B CD2 1 
ATOM   3508 N N   . ALA B 2 133 ? -20.624 -2.922  16.491  1   28.11  ? 303 ALA B N   1 
ATOM   3509 C CA  . ALA B 2 133 ? -20.407 -4.133  17.274  1   27.31  ? 303 ALA B CA  1 
ATOM   3510 C C   . ALA B 2 133 ? -19.591 -5.155  16.479  1   25.61  ? 303 ALA B C   1 
ATOM   3511 O O   . ALA B 2 133 ? -19.819 -6.346  16.616  1   26.11  ? 303 ALA B O   1 
ATOM   3512 C CB  . ALA B 2 133 ? -21.744 -4.706  17.734  1   24.64  ? 303 ALA B CB  1 
ATOM   3513 N N   . PHE B 2 134 ? -18.655 -4.67   15.653  1   27.87  ? 304 PHE B N   1 
ATOM   3514 C CA  . PHE B 2 134 ? -17.731 -5.465  14.857  1   29.7   ? 304 PHE B CA  1 
ATOM   3515 C C   . PHE B 2 134 ? -18.438 -6.256  13.766  1   33.59  ? 304 PHE B C   1 
ATOM   3516 O O   . PHE B 2 134 ? -17.86  -7.18   13.209  1   37.29  ? 304 PHE B O   1 
ATOM   3517 C CB  . PHE B 2 134 ? -16.942 -6.493  15.661  1   32.17  ? 304 PHE B CB  1 
ATOM   3518 C CG  . PHE B 2 134 ? -15.796 -5.916  16.465  1   32.95  ? 304 PHE B CG  1 
ATOM   3519 C CD1 . PHE B 2 134 ? -16.022 -5.311  17.697  1   31.82  ? 304 PHE B CD1 1 
ATOM   3520 C CD2 . PHE B 2 134 ? -14.492 -6.002  15.992  1   31.64  ? 304 PHE B CD2 1 
ATOM   3521 C CE1 . PHE B 2 134 ? -14.953 -4.817  18.441  1   34.02  ? 304 PHE B CE1 1 
ATOM   3522 C CE2 . PHE B 2 134 ? -13.436 -5.499  16.742  1   32.75  ? 304 PHE B CE2 1 
ATOM   3523 C CZ  . PHE B 2 134 ? -13.662 -4.933  17.976  1   31.31  ? 304 PHE B CZ  1 
ATOM   3524 N N   . ASP B 2 135 ? -19.662 -5.86   13.432  1   35.62  ? 305 ASP B N   1 
ATOM   3525 C CA  . ASP B 2 135 ? -20.362 -6.461  12.315  1   38.29  ? 305 ASP B CA  1 
ATOM   3526 C C   . ASP B 2 135 ? -19.876 -5.88   10.994  1   31.69  ? 305 ASP B C   1 
ATOM   3527 O O   . ASP B 2 135 ? -20.595 -5.086  10.379  1   27.2   ? 305 ASP B O   1 
ATOM   3528 C CB  . ASP B 2 135 ? -21.866 -6.388  12.513  1   43.16  ? 305 ASP B CB  1 
ATOM   3529 C CG  . ASP B 2 135 ? -22.332 -7.325  13.603  1   54.21  ? 305 ASP B CG  1 
ATOM   3530 O OD1 . ASP B 2 135 ? -21.501 -8.211  13.965  1   63.41  ? 305 ASP B OD1 1 
ATOM   3531 O OD2 . ASP B 2 135 ? -23.458 -7.092  14.126  1   53.37  ? 305 ASP B OD2 1 
ATOM   3532 N N   . LEU B 2 136 ? -18.682 -6.315  10.567  1   28.24  ? 306 LEU B N   1 
ATOM   3533 C CA  . LEU B 2 136 ? -17.979 -5.7    9.444   1   29.24  ? 306 LEU B CA  1 
ATOM   3534 C C   . LEU B 2 136 ? -18.154 -6.492  8.146   1   27.79  ? 306 LEU B C   1 
ATOM   3535 O O   . LEU B 2 136 ? -18.045 -5.942  7.058   1   31.88  ? 306 LEU B O   1 
ATOM   3536 C CB  . LEU B 2 136 ? -16.502 -5.514  9.787   1   29.68  ? 306 LEU B CB  1 
ATOM   3537 C CG  . LEU B 2 136 ? -16.175 -4.604  10.976  1   28.38  ? 306 LEU B CG  1 
ATOM   3538 C CD1 . LEU B 2 136 ? -14.814 -3.983  10.736  1   26.46  ? 306 LEU B CD1 1 
ATOM   3539 C CD2 . LEU B 2 136 ? -17.208 -3.518  11.187  1   26.22  ? 306 LEU B CD2 1 
ATOM   3540 N N   . ALA B 2 137 ? -18.427 -7.791  8.254   1   28.97  ? 307 ALA B N   1 
ATOM   3541 C CA  . ALA B 2 137 ? -18.599 -8.663  7.098   1   26.28  ? 307 ALA B CA  1 
ATOM   3542 C C   . ALA B 2 137 ? -19.987 -8.504  6.465   1   25.71  ? 307 ALA B C   1 
ATOM   3543 O O   . ALA B 2 137 ? -20.763 -9.453  6.42    1   29.02  ? 307 ALA B O   1 
ATOM   3544 C CB  . ALA B 2 137 ? -18.363 -10.084 7.531   1   23.45  ? 307 ALA B CB  1 
ATOM   3545 N N   . ALA B 2 138 ? -20.26  -7.308  5.945   1   23.63  ? 308 ALA B N   1 
ATOM   3546 C CA  . ALA B 2 138 ? -21.518 -6.947  5.323   1   29.51  ? 308 ALA B CA  1 
ATOM   3547 C C   . ALA B 2 138 ? -21.535 -7.337  3.849   1   31.37  ? 308 ALA B C   1 
ATOM   3548 O O   . ALA B 2 138 ? -20.564 -7.139  3.143   1   37.43  ? 308 ALA B O   1 
ATOM   3549 C CB  . ALA B 2 138 ? -21.708 -5.448  5.442   1   30.18  ? 308 ALA B CB  1 
ATOM   3550 N N   . PRO B 2 139 ? -22.658 -7.88   3.344   1   33.14  ? 309 PRO B N   1 
ATOM   3551 C CA  . PRO B 2 139 ? -22.901 -7.976  1.907   1   30.35  ? 309 PRO B CA  1 
ATOM   3552 C C   . PRO B 2 139 ? -22.831 -6.605  1.274   1   29.71  ? 309 PRO B C   1 
ATOM   3553 O O   . PRO B 2 139 ? -23.342 -5.651  1.838   1   38.96  ? 309 PRO B O   1 
ATOM   3554 C CB  . PRO B 2 139 ? -24.357 -8.482  1.827   1   29.53  ? 309 PRO B CB  1 
ATOM   3555 C CG  . PRO B 2 139 ? -24.562 -9.217  3.128   1   30.18  ? 309 PRO B CG  1 
ATOM   3556 C CD  . PRO B 2 139 ? -23.775 -8.412  4.148   1   32.8   ? 309 PRO B CD  1 
ATOM   3557 N N   . THR B 2 140 ? -22.236 -6.554  0.085   1   29.88  ? 310 THR B N   1 
ATOM   3558 C CA  . THR B 2 140 ? -22.17  -5.376  -0.768  1   29.73  ? 310 THR B CA  1 
ATOM   3559 C C   . THR B 2 140 ? -22.821 -5.667  -2.122  1   29.04  ? 310 THR B C   1 
ATOM   3560 O O   . THR B 2 140 ? -23.042 -6.825  -2.485  1   28.72  ? 310 THR B O   1 
ATOM   3561 C CB  . THR B 2 140 ? -20.71  -4.995  -1.015  1   26.27  ? 310 THR B CB  1 
ATOM   3562 O OG1 . THR B 2 140 ? -20.112 -6.036  -1.787  1   26.83  ? 310 THR B OG1 1 
ATOM   3563 C CG2 . THR B 2 140 ? -19.957 -4.784  0.277   1   27.3   ? 310 THR B CG2 1 
ATOM   3564 N N   . ILE B 2 141 ? -23.052 -4.592  -2.879  1   27.98  ? 311 ILE B N   1 
ATOM   3565 C CA  . ILE B 2 141 ? -23.487 -4.695  -4.259  1   31.37  ? 311 ILE B CA  1 
ATOM   3566 C C   . ILE B 2 141 ? -22.55  -5.64   -5.012  1   32.78  ? 311 ILE B C   1 
ATOM   3567 O O   . ILE B 2 141 ? -23.02  -6.527  -5.73   1   34.78  ? 311 ILE B O   1 
ATOM   3568 C CB  . ILE B 2 141 ? -23.551 -3.288  -4.89   1   31.92  ? 311 ILE B CB  1 
ATOM   3569 C CG1 . ILE B 2 141 ? -24.701 -2.47   -4.293  1   29.3   ? 311 ILE B CG1 1 
ATOM   3570 C CG2 . ILE B 2 141 ? -23.647 -3.35   -6.409  1   29.45  ? 311 ILE B CG2 1 
ATOM   3571 C CD1 . ILE B 2 141 ? -24.575 -0.967  -4.497  1   26.6   ? 311 ILE B CD1 1 
ATOM   3572 N N   . ASN B 2 142 ? -21.233 -5.469  -4.821  1   32.09  ? 312 ASN B N   1 
ATOM   3573 C CA  . ASN B 2 142 ? -20.231 -6.194  -5.601  1   32.99  ? 312 ASN B CA  1 
ATOM   3574 C C   . ASN B 2 142 ? -20.273 -7.691  -5.342  1   33.01  ? 312 ASN B C   1 
ATOM   3575 O O   . ASN B 2 142 ? -20.002 -8.479  -6.256  1   34.78  ? 312 ASN B O   1 
ATOM   3576 C CB  . ASN B 2 142 ? -18.797 -5.749  -5.335  1   35.55  ? 312 ASN B CB  1 
ATOM   3577 C CG  . ASN B 2 142 ? -18.417 -4.573  -6.202  1   45.71  ? 312 ASN B CG  1 
ATOM   3578 O OD1 . ASN B 2 142 ? -19.284 -3.811  -6.658  1   49.98  ? 312 ASN B OD1 1 
ATOM   3579 N ND2 . ASN B 2 142 ? -17.125 -4.399  -6.423  1   42.69  ? 312 ASN B ND2 1 
ATOM   3580 N N   . GLN B 2 143 ? -20.527 -8.065  -4.079  1   32.97  ? 313 GLN B N   1 
ATOM   3581 C CA  . GLN B 2 143 ? -20.607 -9.473  -3.727  1   32.53  ? 313 GLN B CA  1 
ATOM   3582 C C   . GLN B 2 143 ? -21.702 -10.158 -4.545  1   33.21  ? 313 GLN B C   1 
ATOM   3583 O O   . GLN B 2 143 ? -21.531 -11.321 -4.899  1   34.9   ? 313 GLN B O   1 
ATOM   3584 C CB  . GLN B 2 143 ? -20.74  -9.636  -2.217  1   31.32  ? 313 GLN B CB  1 
ATOM   3585 C CG  . GLN B 2 143 ? -19.412 -9.449  -1.487  1   31.05  ? 313 GLN B CG  1 
ATOM   3586 C CD  . GLN B 2 143 ? -19.571 -9.617  0.008   1   31.56  ? 313 GLN B CD  1 
ATOM   3587 O OE1 . GLN B 2 143 ? -20.034 -10.663 0.497   1   28.53  ? 313 GLN B OE1 1 
ATOM   3588 N NE2 . GLN B 2 143 ? -19.228 -8.565  0.74    1   31.06  ? 313 GLN B NE2 1 
ATOM   3589 N N   . PHE B 2 144 ? -22.802 -9.429  -4.848  1   30.64  ? 314 PHE B N   1 
ATOM   3590 C CA  . PHE B 2 144 ? -23.914 -9.958  -5.619  1   25.5   ? 314 PHE B CA  1 
ATOM   3591 C C   . PHE B 2 144 ? -23.603 -9.891  -7.111  1   27     ? 314 PHE B C   1 
ATOM   3592 O O   . PHE B 2 144 ? -23.848 -10.863 -7.83   1   27.55  ? 314 PHE B O   1 
ATOM   3593 C CB  . PHE B 2 144 ? -25.215 -9.222  -5.333  1   23.6   ? 314 PHE B CB  1 
ATOM   3594 C CG  . PHE B 2 144 ? -25.803 -9.584  -3.988  1   22.33  ? 314 PHE B CG  1 
ATOM   3595 C CD1 . PHE B 2 144 ? -26.434 -10.806 -3.803  1   22.64  ? 314 PHE B CD1 1 
ATOM   3596 C CD2 . PHE B 2 144 ? -25.707 -8.707  -2.918  1   22.61  ? 314 PHE B CD2 1 
ATOM   3597 C CE1 . PHE B 2 144 ? -26.957 -11.152 -2.566  1   23.29  ? 314 PHE B CE1 1 
ATOM   3598 C CE2 . PHE B 2 144 ? -26.234 -9.062  -1.678  1   25.14  ? 314 PHE B CE2 1 
ATOM   3599 C CZ  . PHE B 2 144 ? -26.873 -10.276 -1.505  1   23.34  ? 314 PHE B CZ  1 
ATOM   3600 N N   . LEU B 2 145 ? -23.083 -8.745  -7.575  1   25.88  ? 315 LEU B N   1 
ATOM   3601 C CA  . LEU B 2 145 ? -22.726 -8.585  -8.981  1   27.03  ? 315 LEU B CA  1 
ATOM   3602 C C   . LEU B 2 145 ? -21.88  -9.753  -9.498  1   25.87  ? 315 LEU B C   1 
ATOM   3603 O O   . LEU B 2 145 ? -22.181 -10.308 -10.555 1   25.05  ? 315 LEU B O   1 
ATOM   3604 C CB  . LEU B 2 145 ? -22.02  -7.254  -9.231  1   25.67  ? 315 LEU B CB  1 
ATOM   3605 C CG  . LEU B 2 145 ? -22.919 -6.024  -9.368  1   23.6   ? 315 LEU B CG  1 
ATOM   3606 C CD1 . LEU B 2 145 ? -22.029 -4.822  -9.629  1   22.72  ? 315 LEU B CD1 1 
ATOM   3607 C CD2 . LEU B 2 145 ? -23.976 -6.185  -10.451 1   19.02  ? 315 LEU B CD2 1 
ATOM   3608 N N   . THR B 2 146 ? -20.831 -10.108 -8.746  1   24.56  ? 316 THR B N   1 
ATOM   3609 C CA  . THR B 2 146 ? -19.835 -11.055 -9.224  1   27.33  ? 316 THR B CA  1 
ATOM   3610 C C   . THR B 2 146 ? -20.483 -12.43  -9.391  1   27.67  ? 316 THR B C   1 
ATOM   3611 O O   . THR B 2 146 ? -20.062 -13.211 -10.238 1   27.59  ? 316 THR B O   1 
ATOM   3612 C CB  . THR B 2 146 ? -18.563 -11.103 -8.355  1   24.25  ? 316 THR B CB  1 
ATOM   3613 O OG1 . THR B 2 146 ? -18.966 -11.525 -7.053  1   26.33  ? 316 THR B OG1 1 
ATOM   3614 C CG2 . THR B 2 146 ? -17.832 -9.784  -8.242  1   19.13  ? 316 THR B CG2 1 
ATOM   3615 N N   . GLN B 2 147 ? -21.478 -12.748 -8.56   1   29.78  ? 317 GLN B N   1 
ATOM   3616 C CA  . GLN B 2 147 ? -22.207 -14.008 -8.72   1   31.69  ? 317 GLN B CA  1 
ATOM   3617 C C   . GLN B 2 147 ? -23.183 -13.948 -9.896  1   28.19  ? 317 GLN B C   1 
ATOM   3618 O O   . GLN B 2 147 ? -23.373 -14.94  -10.593 1   29.79  ? 317 GLN B O   1 
ATOM   3619 C CB  . GLN B 2 147 ? -23.073 -14.356 -7.518  1   28.42  ? 317 GLN B CB  1 
ATOM   3620 C CG  . GLN B 2 147 ? -22.291 -14.472 -6.227  1   28.13  ? 317 GLN B CG  1 
ATOM   3621 C CD  . GLN B 2 147 ? -23.12  -15.058 -5.112  1   29.05  ? 317 GLN B CD  1 
ATOM   3622 O OE1 . GLN B 2 147 ? -22.813 -14.859 -3.938  1   35.64  ? 317 GLN B OE1 1 
ATOM   3623 N NE2 . GLN B 2 147 ? -24.164 -15.794 -5.456  1   27.27  ? 317 GLN B NE2 1 
ATOM   3624 N N   . TYR B 2 148 ? -23.828 -12.795 -10.078 1   25.34  ? 318 TYR B N   1 
ATOM   3625 C CA  . TYR B 2 148 ? -24.691 -12.604 -11.237 1   27.84  ? 318 TYR B CA  1 
ATOM   3626 C C   . TYR B 2 148 ? -23.879 -12.716 -12.532 1   26.94  ? 318 TYR B C   1 
ATOM   3627 O O   . TYR B 2 148 ? -24.353 -13.298 -13.511 1   26.25  ? 318 TYR B O   1 
ATOM   3628 C CB  . TYR B 2 148 ? -25.368 -11.233 -11.187 1   26.1   ? 318 TYR B CB  1 
ATOM   3629 C CG  . TYR B 2 148 ? -26.275 -10.984 -9.993  1   28.1   ? 318 TYR B CG  1 
ATOM   3630 C CD1 . TYR B 2 148 ? -26.626 -11.992 -9.106  1   25.42  ? 318 TYR B CD1 1 
ATOM   3631 C CD2 . TYR B 2 148 ? -26.818 -9.725  -9.786  1   29.03  ? 318 TYR B CD2 1 
ATOM   3632 C CE1 . TYR B 2 148 ? -27.459 -11.726 -8.033  1   26.42  ? 318 TYR B CE1 1 
ATOM   3633 C CE2 . TYR B 2 148 ? -27.677 -9.465  -8.735  1   26.71  ? 318 TYR B CE2 1 
ATOM   3634 C CZ  . TYR B 2 148 ? -28.003 -10.467 -7.848  1   26.8   ? 318 TYR B CZ  1 
ATOM   3635 O OH  . TYR B 2 148 ? -28.844 -10.19  -6.797  1   26.3   ? 318 TYR B OH  1 
ATOM   3636 N N   . PHE B 2 149 ? -22.67  -12.136 -12.531 1   25.8   ? 319 PHE B N   1 
ATOM   3637 C CA  . PHE B 2 149 ? -21.751 -12.19  -13.668 1   27.47  ? 319 PHE B CA  1 
ATOM   3638 C C   . PHE B 2 149 ? -21.594 -13.61  -14.224 1   26.44  ? 319 PHE B C   1 
ATOM   3639 O O   . PHE B 2 149 ? -21.528 -13.784 -15.44  1   26.04  ? 319 PHE B O   1 
ATOM   3640 C CB  . PHE B 2 149 ? -20.368 -11.643 -13.321 1   22.85  ? 319 PHE B CB  1 
ATOM   3641 C CG  . PHE B 2 149 ? -20.314 -10.139 -13.142 1   23.88  ? 319 PHE B CG  1 
ATOM   3642 C CD1 . PHE B 2 149 ? -21.401 -9.342  -13.49  1   23.69  ? 319 PHE B CD1 1 
ATOM   3643 C CD2 . PHE B 2 149 ? -19.162 -9.532  -12.636 1   24.66  ? 319 PHE B CD2 1 
ATOM   3644 C CE1 . PHE B 2 149 ? -21.331 -7.966  -13.341 1   25.05  ? 319 PHE B CE1 1 
ATOM   3645 C CE2 . PHE B 2 149 ? -19.098 -8.155  -12.469 1   24.9   ? 319 PHE B CE2 1 
ATOM   3646 C CZ  . PHE B 2 149 ? -20.181 -7.378  -12.834 1   28.32  ? 319 PHE B CZ  1 
ATOM   3647 N N   . LEU B 2 150 ? -21.593 -14.617 -13.341 1   25.91  ? 320 LEU B N   1 
ATOM   3648 C CA  . LEU B 2 150 ? -21.494 -16.019 -13.728 1   28.98  ? 320 LEU B CA  1 
ATOM   3649 C C   . LEU B 2 150 ? -22.666 -16.5   -14.604 1   31.55  ? 320 LEU B C   1 
ATOM   3650 O O   . LEU B 2 150 ? -22.642 -17.639 -15.089 1   31.55  ? 320 LEU B O   1 
ATOM   3651 C CB  . LEU B 2 150 ? -21.355 -16.882 -12.473 1   28.03  ? 320 LEU B CB  1 
ATOM   3652 C CG  . LEU B 2 150 ? -20.088 -16.686 -11.628 1   30.84  ? 320 LEU B CG  1 
ATOM   3653 C CD1 . LEU B 2 150 ? -20.174 -17.531 -10.354 1   28.34  ? 320 LEU B CD1 1 
ATOM   3654 C CD2 . LEU B 2 150 ? -18.8   -16.992 -12.388 1   26.49  ? 320 LEU B CD2 1 
ATOM   3655 N N   . HIS B 2 151 ? -23.695 -15.662 -14.804 1   30.75  ? 321 HIS B N   1 
ATOM   3656 C CA  . HIS B 2 151 ? -24.839 -16.066 -15.613 1   33.38  ? 321 HIS B CA  1 
ATOM   3657 C C   . HIS B 2 151 ? -24.755 -15.46  -17.017 1   35.46  ? 321 HIS B C   1 
ATOM   3658 O O   . HIS B 2 151 ? -25.671 -15.603 -17.818 1   42.1   ? 321 HIS B O   1 
ATOM   3659 C CB  . HIS B 2 151 ? -26.157 -15.751 -14.891 1   32.58  ? 321 HIS B CB  1 
ATOM   3660 C CG  . HIS B 2 151 ? -26.352 -16.525 -13.627 1   34.43  ? 321 HIS B CG  1 
ATOM   3661 N ND1 . HIS B 2 151 ? -27.414 -17.39  -13.439 1   31.8   ? 321 HIS B ND1 1 
ATOM   3662 C CD2 . HIS B 2 151 ? -25.638 -16.534 -12.47  1   33.22  ? 321 HIS B CD2 1 
ATOM   3663 C CE1 . HIS B 2 151 ? -27.314 -17.935 -12.225 1   31.04  ? 321 HIS B CE1 1 
ATOM   3664 N NE2 . HIS B 2 151 ? -26.241 -17.434 -11.619 1   31.55  ? 321 HIS B NE2 1 
ATOM   3665 N N   . GLN B 2 152 ? -23.678 -14.733 -17.306 1   38.21  ? 322 GLN B N   1 
ATOM   3666 C CA  . GLN B 2 152 ? -23.476 -14.203 -18.64  1   41.71  ? 322 GLN B CA  1 
ATOM   3667 C C   . GLN B 2 152 ? -23.174 -15.354 -19.593 1   47.98  ? 322 GLN B C   1 
ATOM   3668 O O   . GLN B 2 152 ? -22.491 -16.314 -19.227 1   41.28  ? 322 GLN B O   1 
ATOM   3669 C CB  . GLN B 2 152 ? -22.258 -13.294 -18.706 1   39.04  ? 322 GLN B CB  1 
ATOM   3670 C CG  . GLN B 2 152 ? -22.4   -11.973 -17.972 1   41.45  ? 322 GLN B CG  1 
ATOM   3671 C CD  . GLN B 2 152 ? -21.062 -11.261 -17.91  1   43.81  ? 322 GLN B CD  1 
ATOM   3672 O OE1 . GLN B 2 152 ? -20.818 -10.326 -18.684 1   40.68  ? 322 GLN B OE1 1 
ATOM   3673 N NE2 . GLN B 2 152 ? -20.171 -11.725 -17.04  1   36.27  ? 322 GLN B NE2 1 
ATOM   3674 N N   . GLN B 2 153 ? -23.669 -15.209 -20.831 1   58.93  ? 323 GLN B N   1 
ATOM   3675 C CA  . GLN B 2 153 ? -23.533 -16.224 -21.862 1   64.55  ? 323 GLN B CA  1 
ATOM   3676 C C   . GLN B 2 153 ? -23.086 -15.583 -23.182 1   64.49  ? 323 GLN B C   1 
ATOM   3677 O O   . GLN B 2 153 ? -23.941 -15.196 -23.984 1   67.27  ? 323 GLN B O   1 
ATOM   3678 C CB  . GLN B 2 153 ? -24.874 -16.96  -21.979 1   65.84  ? 323 GLN B CB  1 
ATOM   3679 C CG  . GLN B 2 153 ? -24.875 -18.155 -22.934 1   81.19  ? 323 GLN B CG  1 
ATOM   3680 C CD  . GLN B 2 153 ? -24.426 -19.461 -22.305 1   89.97  ? 323 GLN B CD  1 
ATOM   3681 O OE1 . GLN B 2 153 ? -24.859 -19.816 -21.201 1   95.36  ? 323 GLN B OE1 1 
ATOM   3682 N NE2 . GLN B 2 153 ? -23.575 -20.202 -23.011 1   75.48  ? 323 GLN B NE2 1 
ATOM   3683 N N   . PRO B 2 154 ? -21.758 -15.421 -23.463 1   57.48  ? 324 PRO B N   1 
ATOM   3684 C CA  . PRO B 2 154 ? -20.662 -15.681 -22.506 1   47.84  ? 324 PRO B CA  1 
ATOM   3685 C C   . PRO B 2 154 ? -20.265 -14.432 -21.718 1   39.45  ? 324 PRO B C   1 
ATOM   3686 O O   . PRO B 2 154 ? -20.872 -13.376 -21.886 1   35.64  ? 324 PRO B O   1 
ATOM   3687 C CB  . PRO B 2 154 ? -19.527 -16.064 -23.466 1   45.79  ? 324 PRO B CB  1 
ATOM   3688 C CG  . PRO B 2 154 ? -19.73  -15.114 -24.631 1   45.28  ? 324 PRO B CG  1 
ATOM   3689 C CD  . PRO B 2 154 ? -21.242 -14.965 -24.769 1   46.97  ? 324 PRO B CD  1 
ATOM   3690 N N   . ALA B 2 155 ? -19.188 -14.531 -20.928 1   34.22  ? 325 ALA B N   1 
ATOM   3691 C CA  . ALA B 2 155 ? -18.704 -13.383 -20.169 1   33.03  ? 325 ALA B CA  1 
ATOM   3692 C C   . ALA B 2 155 ? -18.355 -12.22  -21.103 1   35.43  ? 325 ALA B C   1 
ATOM   3693 O O   . ALA B 2 155 ? -17.954 -12.421 -22.251 1   40.3   ? 325 ALA B O   1 
ATOM   3694 C CB  . ALA B 2 155 ? -17.541 -13.789 -19.309 1   29.2   ? 325 ALA B CB  1 
ATOM   3695 N N   . ASN B 2 156 ? -18.55  -10.992 -20.607 1   33.6   ? 326 ASN B N   1 
ATOM   3696 C CA  . ASN B 2 156 ? -18.411 -9.788  -21.408 1   31.66  ? 326 ASN B CA  1 
ATOM   3697 C C   . ASN B 2 156 ? -17.983 -8.682  -20.456 1   34.11  ? 326 ASN B C   1 
ATOM   3698 O O   . ASN B 2 156 ? -18.717 -8.345  -19.532 1   37.99  ? 326 ASN B O   1 
ATOM   3699 C CB  . ASN B 2 156 ? -19.683 -9.434  -22.177 1   29.83  ? 326 ASN B CB  1 
ATOM   3700 C CG  . ASN B 2 156 ? -19.517 -8.236  -23.09  1   34.15  ? 326 ASN B CG  1 
ATOM   3701 O OD1 . ASN B 2 156 ? -18.842 -7.262  -22.74  1   37.51  ? 326 ASN B OD1 1 
ATOM   3702 N ND2 . ASN B 2 156 ? -20.127 -8.265  -24.267 1   35.71  ? 326 ASN B ND2 1 
ATOM   3703 N N   . CYS B 2 157 ? -16.779 -8.152  -20.693 1   33.81  ? 327 CYS B N   1 
ATOM   3704 C CA  . CYS B 2 157 ? -16.073 -7.325  -19.734 1   34.02  ? 327 CYS B CA  1 
ATOM   3705 C C   . CYS B 2 157 ? -16.673 -5.935  -19.68  1   28.53  ? 327 CYS B C   1 
ATOM   3706 O O   . CYS B 2 157 ? -16.628 -5.304  -18.637 1   26.36  ? 327 CYS B O   1 
ATOM   3707 C CB  . CYS B 2 157 ? -14.598 -7.255  -20.108 1   48.72  ? 327 CYS B CB  1 
ATOM   3708 S SG  . CYS B 2 157 ? -13.809 -8.829  -19.694 1   64.05  ? 327 CYS B SG  1 
ATOM   3709 N N   . LYS B 2 158 ? -17.191 -5.468  -20.82  1   28.69  ? 328 LYS B N   1 
ATOM   3710 C CA  . LYS B 2 158 ? -17.878 -4.191  -20.854 1   30.03  ? 328 LYS B CA  1 
ATOM   3711 C C   . LYS B 2 158 ? -19.102 -4.285  -19.946 1   28.74  ? 328 LYS B C   1 
ATOM   3712 O O   . LYS B 2 158 ? -19.334 -3.399  -19.127 1   28.71  ? 328 LYS B O   1 
ATOM   3713 C CB  . LYS B 2 158 ? -18.207 -3.784  -22.292 1   30.13  ? 328 LYS B CB  1 
ATOM   3714 C CG  . LYS B 2 158 ? -17.008 -3.447  -23.152 1   32.45  ? 328 LYS B CG  1 
ATOM   3715 C CD  . LYS B 2 158 ? -17.415 -3.271  -24.613 1   42.11  ? 328 LYS B CD  1 
ATOM   3716 C CE  . LYS B 2 158 ? -18.569 -2.315  -24.788 1   46.31  ? 328 LYS B CE  1 
ATOM   3717 N NZ  . LYS B 2 158 ? -19.069 -2.113  -26.159 1   44.3   ? 328 LYS B NZ  1 
ATOM   3718 N N   . VAL B 2 159 ? -19.838 -5.396  -20.063 1   29.29  ? 329 VAL B N   1 
ATOM   3719 C CA  . VAL B 2 159 ? -20.996 -5.668  -19.217 1   30.08  ? 329 VAL B CA  1 
ATOM   3720 C C   . VAL B 2 159 ? -20.577 -5.634  -17.744 1   27.78  ? 329 VAL B C   1 
ATOM   3721 O O   . VAL B 2 159 ? -21.223 -4.975  -16.935 1   24.78  ? 329 VAL B O   1 
ATOM   3722 C CB  . VAL B 2 159 ? -21.744 -6.972  -19.57  1   26.06  ? 329 VAL B CB  1 
ATOM   3723 C CG1 . VAL B 2 159 ? -22.903 -7.242  -18.615 1   26.55  ? 329 VAL B CG1 1 
ATOM   3724 C CG2 . VAL B 2 159 ? -22.241 -6.929  -20.997 1   23.96  ? 329 VAL B CG2 1 
ATOM   3725 N N   . GLU B 2 160 ? -19.484 -6.325  -17.415 1   27.36  ? 330 GLU B N   1 
ATOM   3726 C CA  . GLU B 2 160 ? -19.073 -6.442  -16.029 1   30.65  ? 330 GLU B CA  1 
ATOM   3727 C C   . GLU B 2 160 ? -18.727 -5.074  -15.466 1   34.89  ? 330 GLU B C   1 
ATOM   3728 O O   . GLU B 2 160 ? -19.305 -4.702  -14.444 1   41.19  ? 330 GLU B O   1 
ATOM   3729 C CB  . GLU B 2 160 ? -17.948 -7.447  -15.839 1   29.98  ? 330 GLU B CB  1 
ATOM   3730 C CG  . GLU B 2 160 ? -18.43  -8.863  -16.125 1   29.84  ? 330 GLU B CG  1 
ATOM   3731 C CD  . GLU B 2 160 ? -17.378 -9.934  -15.976 1   29.98  ? 330 GLU B CD  1 
ATOM   3732 O OE1 . GLU B 2 160 ? -16.382 -9.712  -15.255 1   31.88  ? 330 GLU B OE1 1 
ATOM   3733 O OE2 . GLU B 2 160 ? -17.56  -10.989 -16.6   1   30.9   ? 330 GLU B OE2 1 
ATOM   3734 N N   . SER B 2 161 ? -17.855 -4.329  -16.169 1   32.4   ? 331 SER B N   1 
ATOM   3735 C CA  . SER B 2 161 ? -17.369 -3.025  -15.716 1   30.62  ? 331 SER B CA  1 
ATOM   3736 C C   . SER B 2 161 ? -18.502 -2.002  -15.637 1   30.37  ? 331 SER B C   1 
ATOM   3737 O O   . SER B 2 161 ? -18.48  -1.14   -14.753 1   32.23  ? 331 SER B O   1 
ATOM   3738 C CB  . SER B 2 161 ? -16.236 -2.467  -16.572 1   24.86  ? 331 SER B CB  1 
ATOM   3739 O OG  . SER B 2 161 ? -15.104 -3.298  -16.478 1   25.2   ? 331 SER B OG  1 
ATOM   3740 N N   . LEU B 2 162 ? -19.431 -2.053  -16.605 1   28.31  ? 332 LEU B N   1 
ATOM   3741 C CA  . LEU B 2 162 ? -20.503 -1.073  -16.656 1   29.07  ? 332 LEU B CA  1 
ATOM   3742 C C   . LEU B 2 162 ? -21.417 -1.262  -15.442 1   30.24  ? 332 LEU B C   1 
ATOM   3743 O O   . LEU B 2 162 ? -21.846 -0.283  -14.829 1   29.41  ? 332 LEU B O   1 
ATOM   3744 C CB  . LEU B 2 162 ? -21.278 -1.115  -17.974 1   27.49  ? 332 LEU B CB  1 
ATOM   3745 C CG  . LEU B 2 162 ? -22.45  -0.132  -18.095 1   27.47  ? 332 LEU B CG  1 
ATOM   3746 C CD1 . LEU B 2 162 ? -22.012 1.304   -17.82  1   25.34  ? 332 LEU B CD1 1 
ATOM   3747 C CD2 . LEU B 2 162 ? -23.095 -0.207  -19.473 1   28.07  ? 332 LEU B CD2 1 
ATOM   3748 N N   . ALA B 2 163 ? -21.728 -2.527  -15.123 1   30.94  ? 333 ALA B N   1 
ATOM   3749 C CA  . ALA B 2 163 ? -22.521 -2.869  -13.955 1   27.14  ? 333 ALA B CA  1 
ATOM   3750 C C   . ALA B 2 163 ? -21.814 -2.387  -12.692 1   29.15  ? 333 ALA B C   1 
ATOM   3751 O O   . ALA B 2 163 ? -22.48  -1.82   -11.832 1   28.68  ? 333 ALA B O   1 
ATOM   3752 C CB  . ALA B 2 163 ? -22.769 -4.359  -13.911 1   25.2   ? 333 ALA B CB  1 
ATOM   3753 N N   . MET B 2 164 ? -20.49  -2.63   -12.581 1   29.1   ? 334 MET B N   1 
ATOM   3754 C CA  . MET B 2 164 ? -19.697 -2.189  -11.435 1   32.98  ? 334 MET B CA  1 
ATOM   3755 C C   . MET B 2 164 ? -19.895 -0.681  -11.257 1   33.19  ? 334 MET B C   1 
ATOM   3756 O O   . MET B 2 164 ? -20.074 -0.203  -10.134 1   36.68  ? 334 MET B O   1 
ATOM   3757 C CB  . MET B 2 164 ? -18.184 -2.441  -11.601 1   36.06  ? 334 MET B CB  1 
ATOM   3758 C CG  . MET B 2 164 ? -17.668 -3.86   -11.301 1   39.39  ? 334 MET B CG  1 
ATOM   3759 S SD  . MET B 2 164 ? -18.065 -4.408  -9.625  1   51.09  ? 334 MET B SD  1 
ATOM   3760 C CE  . MET B 2 164 ? -17.516 -6.118  -9.704  1   59.52  ? 334 MET B CE  1 
ATOM   3761 N N   . PHE B 2 165 ? -19.858 0.034   -12.389 1   29.1   ? 335 PHE B N   1 
ATOM   3762 C CA  . PHE B 2 165 ? -19.894 1.485   -12.465 1   28.55  ? 335 PHE B CA  1 
ATOM   3763 C C   . PHE B 2 165 ? -21.231 2.012   -11.944 1   28.61  ? 335 PHE B C   1 
ATOM   3764 O O   . PHE B 2 165 ? -21.288 2.931   -11.133 1   29.74  ? 335 PHE B O   1 
ATOM   3765 C CB  . PHE B 2 165 ? -19.601 1.876   -13.92  1   25.86  ? 335 PHE B CB  1 
ATOM   3766 C CG  . PHE B 2 165 ? -19.91  3.311   -14.307 1   25.69  ? 335 PHE B CG  1 
ATOM   3767 C CD1 . PHE B 2 165 ? -19.136 4.368   -13.839 1   25.76  ? 335 PHE B CD1 1 
ATOM   3768 C CD2 . PHE B 2 165 ? -20.984 3.606   -15.131 1   28.09  ? 335 PHE B CD2 1 
ATOM   3769 C CE1 . PHE B 2 165 ? -19.405 5.682   -14.205 1   25.27  ? 335 PHE B CE1 1 
ATOM   3770 C CE2 . PHE B 2 165 ? -21.258 4.922   -15.5   1   27.1   ? 335 PHE B CE2 1 
ATOM   3771 C CZ  . PHE B 2 165 ? -20.477 5.956   -15.032 1   27.01  ? 335 PHE B CZ  1 
ATOM   3772 N N   . LEU B 2 166 ? -22.316 1.411   -12.422 1   29.96  ? 336 LEU B N   1 
ATOM   3773 C CA  . LEU B 2 166 ? -23.663 1.839   -12.091 1   27.84  ? 336 LEU B CA  1 
ATOM   3774 C C   . LEU B 2 166 ? -23.901 1.617   -10.601 1   30.88  ? 336 LEU B C   1 
ATOM   3775 O O   . LEU B 2 166 ? -24.428 2.494   -9.912  1   32.71  ? 336 LEU B O   1 
ATOM   3776 C CB  . LEU B 2 166 ? -24.638 1.063   -12.977 1   25.68  ? 336 LEU B CB  1 
ATOM   3777 C CG  . LEU B 2 166 ? -24.615 1.429   -14.469 1   22.6   ? 336 LEU B CG  1 
ATOM   3778 C CD1 . LEU B 2 166 ? -25.519 0.541   -15.301 1   21.87  ? 336 LEU B CD1 1 
ATOM   3779 C CD2 . LEU B 2 166 ? -24.936 2.884   -14.72  1   19.74  ? 336 LEU B CD2 1 
ATOM   3780 N N   . GLY B 2 167 ? -23.448 0.461   -10.101 1   31.12  ? 337 GLY B N   1 
ATOM   3781 C CA  . GLY B 2 167 ? -23.514 0.154   -8.68   1   28.99  ? 337 GLY B CA  1 
ATOM   3782 C C   . GLY B 2 167 ? -22.75  1.187   -7.862  1   30.77  ? 337 GLY B C   1 
ATOM   3783 O O   . GLY B 2 167 ? -23.212 1.579   -6.798  1   31.2   ? 337 GLY B O   1 
ATOM   3784 N N   . GLU B 2 168 ? -21.595 1.634   -8.375  1   29.01  ? 338 GLU B N   1 
ATOM   3785 C CA  . GLU B 2 168 ? -20.821 2.654   -7.682  1   29     ? 338 GLU B CA  1 
ATOM   3786 C C   . GLU B 2 168 ? -21.582 3.98    -7.646  1   30.73  ? 338 GLU B C   1 
ATOM   3787 O O   . GLU B 2 168 ? -21.631 4.646   -6.608  1   30.56  ? 338 GLU B O   1 
ATOM   3788 C CB  . GLU B 2 168 ? -19.42  2.825   -8.264  1   28.17  ? 338 GLU B CB  1 
ATOM   3789 C CG  . GLU B 2 168 ? -18.35  2.383   -7.277  1   29.41  ? 338 GLU B CG  1 
ATOM   3790 C CD  . GLU B 2 168 ? -16.923 2.347   -7.773  1   30.13  ? 338 GLU B CD  1 
ATOM   3791 O OE1 . GLU B 2 168 ? -16.249 3.412   -7.848  1   29.34  ? 338 GLU B OE1 1 
ATOM   3792 O OE2 . GLU B 2 168 ? -16.491 1.223   -8.087  1   29.57  ? 338 GLU B OE2 1 
ATOM   3793 N N   . LEU B 2 169 ? -22.172 4.37    -8.782  1   28.9   ? 339 LEU B N   1 
ATOM   3794 C CA  . LEU B 2 169 ? -22.928 5.615   -8.836  1   28     ? 339 LEU B CA  1 
ATOM   3795 C C   . LEU B 2 169 ? -23.992 5.634   -7.738  1   25.72  ? 339 LEU B C   1 
ATOM   3796 O O   . LEU B 2 169 ? -24.289 6.681   -7.185  1   24.55  ? 339 LEU B O   1 
ATOM   3797 C CB  . LEU B 2 169 ? -23.542 5.832   -10.221 1   25.65  ? 339 LEU B CB  1 
ATOM   3798 C CG  . LEU B 2 169 ? -22.561 6.196   -11.339 1   27.1   ? 339 LEU B CG  1 
ATOM   3799 C CD1 . LEU B 2 169 ? -23.313 6.374   -12.648 1   26.73  ? 339 LEU B CD1 1 
ATOM   3800 C CD2 . LEU B 2 169 ? -21.75  7.455   -11.031 1   26.57  ? 339 LEU B CD2 1 
ATOM   3801 N N   . SER B 2 170 ? -24.562 4.47    -7.435  1   26.05  ? 340 SER B N   1 
ATOM   3802 C CA  . SER B 2 170 ? -25.628 4.357   -6.45   1   29.93  ? 340 SER B CA  1 
ATOM   3803 C C   . SER B 2 170 ? -25.152 4.692   -5.024  1   28.68  ? 340 SER B C   1 
ATOM   3804 O O   . SER B 2 170 ? -25.934 5.171   -4.217  1   29.81  ? 340 SER B O   1 
ATOM   3805 C CB  . SER B 2 170 ? -26.3   2.985   -6.531  1   28.31  ? 340 SER B CB  1 
ATOM   3806 O OG  . SER B 2 170 ? -25.702 2.07    -5.625  1   29.29  ? 340 SER B OG  1 
ATOM   3807 N N   . LEU B 2 171 ? -23.879 4.439   -4.705  1   27.22  ? 341 LEU B N   1 
ATOM   3808 C CA  . LEU B 2 171 ? -23.328 4.752   -3.399  1   27.22  ? 341 LEU B CA  1 
ATOM   3809 C C   . LEU B 2 171 ? -23.415 6.248   -3.106  1   30.62  ? 341 LEU B C   1 
ATOM   3810 O O   . LEU B 2 171 ? -23.438 6.639   -1.941  1   33.14  ? 341 LEU B O   1 
ATOM   3811 C CB  . LEU B 2 171 ? -21.865 4.314   -3.339  1   28.59  ? 341 LEU B CB  1 
ATOM   3812 C CG  . LEU B 2 171 ? -21.586 2.818   -3.532  1   28.86  ? 341 LEU B CG  1 
ATOM   3813 C CD1 . LEU B 2 171 ? -20.086 2.556   -3.529  1   27.74  ? 341 LEU B CD1 1 
ATOM   3814 C CD2 . LEU B 2 171 ? -22.238 1.985   -2.464  1   25.85  ? 341 LEU B CD2 1 
ATOM   3815 N N   . ILE B 2 172 ? -23.393 7.087   -4.15   1   30.31  ? 342 ILE B N   1 
ATOM   3816 C CA  . ILE B 2 172 ? -23.31  8.53    -3.962  1   30     ? 342 ILE B CA  1 
ATOM   3817 C C   . ILE B 2 172 ? -24.615 9.122   -3.407  1   32.54  ? 342 ILE B C   1 
ATOM   3818 O O   . ILE B 2 172 ? -24.577 10.045  -2.597  1   31.82  ? 342 ILE B O   1 
ATOM   3819 C CB  . ILE B 2 172 ? -22.889 9.239   -5.261  1   27.55  ? 342 ILE B CB  1 
ATOM   3820 C CG1 . ILE B 2 172 ? -21.54  8.734   -5.792  1   26.67  ? 342 ILE B CG1 1 
ATOM   3821 C CG2 . ILE B 2 172 ? -22.92  10.764  -5.093  1   27.99  ? 342 ILE B CG2 1 
ATOM   3822 C CD1 . ILE B 2 172 ? -20.306 9.318   -5.124  1   26.6   ? 342 ILE B CD1 1 
ATOM   3823 N N   . ASP B 2 173 ? -25.763 8.615   -3.866  1   31.86  ? 343 ASP B N   1 
ATOM   3824 C CA  . ASP B 2 173 ? -27.043 9.286   -3.683  1   31.66  ? 343 ASP B CA  1 
ATOM   3825 C C   . ASP B 2 173 ? -27.924 8.497   -2.72   1   31.85  ? 343 ASP B C   1 
ATOM   3826 O O   . ASP B 2 173 ? -28.674 7.62    -3.145  1   35.46  ? 343 ASP B O   1 
ATOM   3827 C CB  . ASP B 2 173 ? -27.732 9.503   -5.022  1   31.1   ? 343 ASP B CB  1 
ATOM   3828 C CG  . ASP B 2 173 ? -26.9   10.33   -5.987  1   33.07  ? 343 ASP B CG  1 
ATOM   3829 O OD1 . ASP B 2 173 ? -26.424 11.382  -5.53   1   35.14  ? 343 ASP B OD1 1 
ATOM   3830 O OD2 . ASP B 2 173 ? -26.723 9.917   -7.169  1   30.29  ? 343 ASP B OD2 1 
ATOM   3831 N N   . ALA B 2 174 ? -27.835 8.837   -1.43   1   32.47  ? 344 ALA B N   1 
ATOM   3832 C CA  . ALA B 2 174 ? -28.59  8.184   -0.366  1   34.77  ? 344 ALA B CA  1 
ATOM   3833 C C   . ALA B 2 174 ? -30.087 8.232   -0.656  1   31.52  ? 344 ALA B C   1 
ATOM   3834 O O   . ALA B 2 174 ? -30.809 7.325   -0.259  1   34.43  ? 344 ALA B O   1 
ATOM   3835 C CB  . ALA B 2 174 ? -28.283 8.819   0.973   1   34.68  ? 344 ALA B CB  1 
ATOM   3836 N N   . ASP B 2 175 ? -30.534 9.305   -1.307  1   28.42  ? 345 ASP B N   1 
ATOM   3837 C CA  . ASP B 2 175 ? -31.866 9.354   -1.878  1   31.35  ? 345 ASP B CA  1 
ATOM   3838 C C   . ASP B 2 175 ? -31.721 9.172   -3.387  1   31.16  ? 345 ASP B C   1 
ATOM   3839 O O   . ASP B 2 175 ? -31.195 10.059  -4.045  1   32.5   ? 345 ASP B O   1 
ATOM   3840 C CB  . ASP B 2 175 ? -32.538 10.686  -1.563  1   30.93  ? 345 ASP B CB  1 
ATOM   3841 C CG  . ASP B 2 175 ? -33.932 10.913  -2.144  1   33.18  ? 345 ASP B CG  1 
ATOM   3842 O OD1 . ASP B 2 175 ? -34.449 9.983   -2.775  1   36.06  ? 345 ASP B OD1 1 
ATOM   3843 O OD2 . ASP B 2 175 ? -34.501 12.025  -1.969  1   30.69  ? 345 ASP B OD2 1 
ATOM   3844 N N   . PRO B 2 176 ? -32.27  8.1     -4.011  1   33.13  ? 346 PRO B N   1 
ATOM   3845 C CA  . PRO B 2 176 ? -33.123 7.117   -3.32   1   29.86  ? 346 PRO B CA  1 
ATOM   3846 C C   . PRO B 2 176 ? -32.486 5.824   -2.839  1   29.19  ? 346 PRO B C   1 
ATOM   3847 O O   . PRO B 2 176 ? -33.199 4.99    -2.284  1   31.22  ? 346 PRO B O   1 
ATOM   3848 C CB  . PRO B 2 176 ? -34.08  6.746   -4.469  1   27.91  ? 346 PRO B CB  1 
ATOM   3849 C CG  . PRO B 2 176 ? -33.14  6.663   -5.667  1   26.39  ? 346 PRO B CG  1 
ATOM   3850 C CD  . PRO B 2 176 ? -32.204 7.856   -5.469  1   28.59  ? 346 PRO B CD  1 
ATOM   3851 N N   . TYR B 2 177 ? -31.189 5.646   -3.104  1   27.59  ? 347 TYR B N   1 
ATOM   3852 C CA  . TYR B 2 177 ? -30.57  4.328   -3.079  1   29.7   ? 347 TYR B CA  1 
ATOM   3853 C C   . TYR B 2 177 ? -30.556 3.685   -1.69   1   28.92  ? 347 TYR B C   1 
ATOM   3854 O O   . TYR B 2 177 ? -30.259 2.498   -1.589  1   29.83  ? 347 TYR B O   1 
ATOM   3855 C CB  . TYR B 2 177 ? -29.216 4.303   -3.807  1   30.62  ? 347 TYR B CB  1 
ATOM   3856 C CG  . TYR B 2 177 ? -29.463 4.549   -5.286  1   32.9   ? 347 TYR B CG  1 
ATOM   3857 C CD1 . TYR B 2 177 ? -30.185 3.632   -6.051  1   29.57  ? 347 TYR B CD1 1 
ATOM   3858 C CD2 . TYR B 2 177 ? -29.052 5.734   -5.878  1   31.69  ? 347 TYR B CD2 1 
ATOM   3859 C CE1 . TYR B 2 177 ? -30.471 3.873   -7.384  1   28.68  ? 347 TYR B CE1 1 
ATOM   3860 C CE2 . TYR B 2 177 ? -29.349 5.984   -7.204  1   31.27  ? 347 TYR B CE2 1 
ATOM   3861 C CZ  . TYR B 2 177 ? -30.054 5.057   -7.952  1   28.6   ? 347 TYR B CZ  1 
ATOM   3862 O OH  . TYR B 2 177 ? -30.324 5.338   -9.256  1   28.71  ? 347 TYR B OH  1 
ATOM   3863 N N   . LEU B 2 178 ? -30.822 4.448   -0.625  1   28.28  ? 348 LEU B N   1 
ATOM   3864 C CA  . LEU B 2 178 ? -30.845 3.826   0.69    1   29.84  ? 348 LEU B CA  1 
ATOM   3865 C C   . LEU B 2 178 ? -32.026 2.869   0.794   1   30.78  ? 348 LEU B C   1 
ATOM   3866 O O   . LEU B 2 178 ? -32.017 2.007   1.665   1   32.11  ? 348 LEU B O   1 
ATOM   3867 C CB  . LEU B 2 178 ? -30.887 4.826   1.842   1   30.01  ? 348 LEU B CB  1 
ATOM   3868 C CG  . LEU B 2 178 ? -29.555 5.425   2.297   1   29.14  ? 348 LEU B CG  1 
ATOM   3869 C CD1 . LEU B 2 178 ? -29.824 6.285   3.544   1   23.02  ? 348 LEU B CD1 1 
ATOM   3870 C CD2 . LEU B 2 178 ? -28.474 4.351   2.532   1   27.57  ? 348 LEU B CD2 1 
ATOM   3871 N N   . LYS B 2 179 ? -33.031 3.044   -0.062  1   33.57  ? 349 LYS B N   1 
ATOM   3872 C CA  . LYS B 2 179 ? -34.281 2.249   0.049   1   37.46  ? 349 LYS B CA  1 
ATOM   3873 C C   . LYS B 2 179 ? -34.125 0.88    -0.61   1   35.72  ? 349 LYS B C   1 
ATOM   3874 O O   . LYS B 2 179 ? -35.016 0.033   -0.438  1   41.09  ? 349 LYS B O   1 
ATOM   3875 C CB  . LYS B 2 179 ? -35.432 3.031   -0.59   1   39.45  ? 349 LYS B CB  1 
ATOM   3876 C CG  . LYS B 2 179 ? -35.306 3.334   -2.068  1   50.39  ? 349 LYS B CG  1 
ATOM   3877 C CD  . LYS B 2 179 ? -36.481 4.113   -2.644  1   51.11  ? 349 LYS B CD  1 
ATOM   3878 C CE  . LYS B 2 179 ? -36.565 5.509   -2.127  1   55.24  ? 349 LYS B CE  1 
ATOM   3879 N NZ  . LYS B 2 179 ? -37.708 6.214   -2.709  1   52.97  ? 349 LYS B NZ  1 
ATOM   3880 N N   . TYR B 2 180 ? -33.031 0.68    -1.325  1   32.1   ? 350 TYR B N   1 
ATOM   3881 C CA  . TYR B 2 180 ? -32.816 -0.593  -1.999  1   31.95  ? 350 TYR B CA  1 
ATOM   3882 C C   . TYR B 2 180 ? -31.678 -1.368  -1.34   1   32.77  ? 350 TYR B C   1 
ATOM   3883 O O   . TYR B 2 180 ? -30.677 -0.785  -0.934  1   37.41  ? 350 TYR B O   1 
ATOM   3884 C CB  . TYR B 2 180 ? -32.539 -0.371  -3.493  1   30.71  ? 350 TYR B CB  1 
ATOM   3885 C CG  . TYR B 2 180 ? -33.589 0.467   -4.22   1   28.51  ? 350 TYR B CG  1 
ATOM   3886 C CD1 . TYR B 2 180 ? -34.88  -0.014  -4.41   1   23.84  ? 350 TYR B CD1 1 
ATOM   3887 C CD2 . TYR B 2 180 ? -33.271 1.738   -4.705  1   26.67  ? 350 TYR B CD2 1 
ATOM   3888 C CE1 . TYR B 2 180 ? -35.827 0.752   -5.073  1   27.88  ? 350 TYR B CE1 1 
ATOM   3889 C CE2 . TYR B 2 180 ? -34.207 2.513   -5.369  1   27.24  ? 350 TYR B CE2 1 
ATOM   3890 C CZ  . TYR B 2 180 ? -35.491 2.016   -5.55   1   29.18  ? 350 TYR B CZ  1 
ATOM   3891 O OH  . TYR B 2 180 ? -36.391 2.785   -6.218  1   24.83  ? 350 TYR B OH  1 
ATOM   3892 N N   . LEU B 2 181 ? -31.832 -2.698  -1.293  1   32.92  ? 351 LEU B N   1 
ATOM   3893 C CA  . LEU B 2 181 ? -30.838 -3.631  -0.779  1   30.48  ? 351 LEU B CA  1 
ATOM   3894 C C   . LEU B 2 181 ? -29.754 -3.853  -1.826  1   29.38  ? 351 LEU B C   1 
ATOM   3895 O O   . LEU B 2 181 ? -30.003 -3.823  -3.033  1   30.79  ? 351 LEU B O   1 
ATOM   3896 C CB  . LEU B 2 181 ? -31.524 -4.963  -0.464  1   31.4   ? 351 LEU B CB  1 
ATOM   3897 C CG  . LEU B 2 181 ? -32.555 -4.957  0.67    1   28.44  ? 351 LEU B CG  1 
ATOM   3898 C CD1 . LEU B 2 181 ? -33.363 -6.239  0.676   1   23.42  ? 351 LEU B CD1 1 
ATOM   3899 C CD2 . LEU B 2 181 ? -31.798 -4.796  1.987   1   28.96  ? 351 LEU B CD2 1 
ATOM   3900 N N   . PRO B 2 182 ? -28.513 -4.131  -1.388  1   29.87  ? 352 PRO B N   1 
ATOM   3901 C CA  . PRO B 2 182 ? -27.425 -4.44   -2.325  1   28.76  ? 352 PRO B CA  1 
ATOM   3902 C C   . PRO B 2 182 ? -27.804 -5.404  -3.448  1   28.25  ? 352 PRO B C   1 
ATOM   3903 O O   . PRO B 2 182 ? -27.471 -5.166  -4.604  1   25.91  ? 352 PRO B O   1 
ATOM   3904 C CB  . PRO B 2 182 ? -26.353 -5.016  -1.385  1   26.55  ? 352 PRO B CB  1 
ATOM   3905 C CG  . PRO B 2 182 ? -26.565 -4.216  -0.132  1   28.24  ? 352 PRO B CG  1 
ATOM   3906 C CD  . PRO B 2 182 ? -28.089 -4.098  0.024   1   27.7   ? 352 PRO B CD  1 
ATOM   3907 N N   . SER B 2 183 ? -28.548 -6.462  -3.111  1   28.87  ? 353 SER B N   1 
ATOM   3908 C CA  . SER B 2 183 ? -28.872 -7.497  -4.078  1   30.91  ? 353 SER B CA  1 
ATOM   3909 C C   . SER B 2 183 ? -29.752 -6.933  -5.196  1   32.03  ? 353 SER B C   1 
ATOM   3910 O O   . SER B 2 183 ? -29.688 -7.412  -6.327  1   34.15  ? 353 SER B O   1 
ATOM   3911 C CB  . SER B 2 183 ? -29.528 -8.701  -3.407  1   33.02  ? 353 SER B CB  1 
ATOM   3912 O OG  . SER B 2 183 ? -30.814 -8.367  -2.896  1   32.92  ? 353 SER B OG  1 
ATOM   3913 N N   . VAL B 2 184 ? -30.578 -5.931  -4.865  1   28.21  ? 354 VAL B N   1 
ATOM   3914 C CA  . VAL B 2 184 ? -31.514 -5.363  -5.814  1   27.16  ? 354 VAL B CA  1 
ATOM   3915 C C   . VAL B 2 184 ? -30.807 -4.314  -6.681  1   27.64  ? 354 VAL B C   1 
ATOM   3916 O O   . VAL B 2 184 ? -30.996 -4.307  -7.907  1   26.03  ? 354 VAL B O   1 
ATOM   3917 C CB  . VAL B 2 184 ? -32.754 -4.794  -5.098  1   25.03  ? 354 VAL B CB  1 
ATOM   3918 C CG1 . VAL B 2 184 ? -33.51  -3.8    -5.971  1   24.62  ? 354 VAL B CG1 1 
ATOM   3919 C CG2 . VAL B 2 184 ? -33.682 -5.905  -4.633  1   24.35  ? 354 VAL B CG2 1 
ATOM   3920 N N   . ILE B 2 185 ? -30.037 -3.4    -6.064  1   23.8   ? 355 ILE B N   1 
ATOM   3921 C CA  . ILE B 2 185 ? -29.258 -2.468  -6.871  1   28.74  ? 355 ILE B CA  1 
ATOM   3922 C C   . ILE B 2 185 ? -28.336 -3.239  -7.821  1   27.79  ? 355 ILE B C   1 
ATOM   3923 O O   . ILE B 2 185 ? -28.165 -2.866  -8.976  1   26.54  ? 355 ILE B O   1 
ATOM   3924 C CB  . ILE B 2 185 ? -28.433 -1.502  -6.008  1   33.35  ? 355 ILE B CB  1 
ATOM   3925 C CG1 . ILE B 2 185 ? -29.336 -0.59   -5.193  1   33.97  ? 355 ILE B CG1 1 
ATOM   3926 C CG2 . ILE B 2 185 ? -27.451 -0.703  -6.872  1   29.08  ? 355 ILE B CG2 1 
ATOM   3927 C CD1 . ILE B 2 185 ? -28.614 0.017   -4.003  1   32.26  ? 355 ILE B CD1 1 
ATOM   3928 N N   . ALA B 2 186 ? -27.748 -4.321  -7.323  1   26.76  ? 356 ALA B N   1 
ATOM   3929 C CA  . ALA B 2 186 ? -26.874 -5.144  -8.136  1   28.89  ? 356 ALA B CA  1 
ATOM   3930 C C   . ALA B 2 186 ? -27.674 -5.761  -9.282  1   27.78  ? 356 ALA B C   1 
ATOM   3931 O O   . ALA B 2 186 ? -27.188 -5.88   -10.406 1   29.34  ? 356 ALA B O   1 
ATOM   3932 C CB  . ALA B 2 186 ? -26.186 -6.201  -7.271  1   25.36  ? 356 ALA B CB  1 
ATOM   3933 N N   . ALA B 2 187 ? -28.901 -6.178  -8.99   1   26.55  ? 357 ALA B N   1 
ATOM   3934 C CA  . ALA B 2 187 ? -29.737 -6.772  -10.019 1   25.89  ? 357 ALA B CA  1 
ATOM   3935 C C   . ALA B 2 187 ? -29.973 -5.718  -11.086 1   26.72  ? 357 ALA B C   1 
ATOM   3936 O O   . ALA B 2 187 ? -29.799 -5.982  -12.274 1   29.34  ? 357 ALA B O   1 
ATOM   3937 C CB  . ALA B 2 187 ? -31.043 -7.27   -9.422  1   27.14  ? 357 ALA B CB  1 
ATOM   3938 N N   . ALA B 2 188 ? -30.34  -4.511  -10.637 1   25.83  ? 358 ALA B N   1 
ATOM   3939 C CA  . ALA B 2 188 ? -30.737 -3.465  -11.554 1   24.9   ? 358 ALA B CA  1 
ATOM   3940 C C   . ALA B 2 188 ? -29.521 -3.086  -12.383 1   28.26  ? 358 ALA B C   1 
ATOM   3941 O O   . ALA B 2 188 ? -29.632 -2.881  -13.589 1   31.63  ? 358 ALA B O   1 
ATOM   3942 C CB  . ALA B 2 188 ? -31.306 -2.303  -10.786 1   23.76  ? 358 ALA B CB  1 
ATOM   3943 N N   . ALA B 2 189 ? -28.359 -3.058  -11.715 1   29.38  ? 359 ALA B N   1 
ATOM   3944 C CA  . ALA B 2 189 ? -27.122 -2.63   -12.33  1   25.94  ? 359 ALA B CA  1 
ATOM   3945 C C   . ALA B 2 189 ? -26.752 -3.635  -13.411 1   28.83  ? 359 ALA B C   1 
ATOM   3946 O O   . ALA B 2 189 ? -26.4   -3.237  -14.523 1   28.54  ? 359 ALA B O   1 
ATOM   3947 C CB  . ALA B 2 189 ? -26.05  -2.468  -11.28  1   23.68  ? 359 ALA B CB  1 
ATOM   3948 N N   . PHE B 2 190 ? -26.86  -4.93   -13.076 1   29.52  ? 360 PHE B N   1 
ATOM   3949 C CA  . PHE B 2 190 ? -26.496 -5.984  -14.004 1   28.67  ? 360 PHE B CA  1 
ATOM   3950 C C   . PHE B 2 190 ? -27.412 -5.917  -15.227 1   29.37  ? 360 PHE B C   1 
ATOM   3951 O O   . PHE B 2 190 ? -26.947 -6.065  -16.364 1   31.61  ? 360 PHE B O   1 
ATOM   3952 C CB  . PHE B 2 190 ? -26.519 -7.353  -13.321 1   27.53  ? 360 PHE B CB  1 
ATOM   3953 C CG  . PHE B 2 190 ? -26.14  -8.48   -14.273 1   27.79  ? 360 PHE B CG  1 
ATOM   3954 C CD1 . PHE B 2 190 ? -24.87  -8.529  -14.844 1   25.03  ? 360 PHE B CD1 1 
ATOM   3955 C CD2 . PHE B 2 190 ? -27.064 -9.473  -14.602 1   27.29  ? 360 PHE B CD2 1 
ATOM   3956 C CE1 . PHE B 2 190 ? -24.542 -9.537  -15.74  1   27.88  ? 360 PHE B CE1 1 
ATOM   3957 C CE2 . PHE B 2 190 ? -26.74  -10.483 -15.5   1   29.67  ? 360 PHE B CE2 1 
ATOM   3958 C CZ  . PHE B 2 190 ? -25.472 -10.515 -16.061 1   30.99  ? 360 PHE B CZ  1 
ATOM   3959 N N   . HIS B 2 191 ? -28.704 -5.638  -15.003 1   24.96  ? 361 HIS B N   1 
ATOM   3960 C CA  . HIS B 2 191 ? -29.64  -5.689  -16.122 1   23.92  ? 361 HIS B CA  1 
ATOM   3961 C C   . HIS B 2 191 ? -29.477 -4.482  -17.034 1   21.61  ? 361 HIS B C   1 
ATOM   3962 O O   . HIS B 2 191 ? -29.589 -4.598  -18.243 1   21.06  ? 361 HIS B O   1 
ATOM   3963 C CB  . HIS B 2 191 ? -31.106 -5.76   -15.695 1   21.2   ? 361 HIS B CB  1 
ATOM   3964 C CG  . HIS B 2 191 ? -31.982 -5.397  -16.841 1   18.68  ? 361 HIS B CG  1 
ATOM   3965 N ND1 . HIS B 2 191 ? -32.291 -6.324  -17.804 1   18.82  ? 361 HIS B ND1 1 
ATOM   3966 C CD2 . HIS B 2 191 ? -32.542 -4.234  -17.227 1   17.91  ? 361 HIS B CD2 1 
ATOM   3967 C CE1 . HIS B 2 191 ? -33.063 -5.744  -18.721 1   19.83  ? 361 HIS B CE1 1 
ATOM   3968 N NE2 . HIS B 2 191 ? -33.229 -4.474  -18.391 1   19.16  ? 361 HIS B NE2 1 
ATOM   3969 N N   . LEU B 2 192 ? -29.212 -3.326  -16.432 1   21.82  ? 362 LEU B N   1 
ATOM   3970 C CA  . LEU B 2 192 ? -29.014 -2.117  -17.193 1   22.52  ? 362 LEU B CA  1 
ATOM   3971 C C   . LEU B 2 192 ? -27.733 -2.26   -18.013 1   26.14  ? 362 LEU B C   1 
ATOM   3972 O O   . LEU B 2 192 ? -27.744 -1.968  -19.218 1   28.59  ? 362 LEU B O   1 
ATOM   3973 C CB  . LEU B 2 192 ? -28.974 -0.947  -16.222 1   22.31  ? 362 LEU B CB  1 
ATOM   3974 C CG  . LEU B 2 192 ? -29.118 0.434   -16.866 1   25.05  ? 362 LEU B CG  1 
ATOM   3975 C CD1 . LEU B 2 192 ? -30.292 0.478   -17.859 1   26.56  ? 362 LEU B CD1 1 
ATOM   3976 C CD2 . LEU B 2 192 ? -29.251 1.519   -15.809 1   25.88  ? 362 LEU B CD2 1 
ATOM   3977 N N   . ALA B 2 193 ? -26.658 -2.759  -17.379 1   22.42  ? 363 ALA B N   1 
ATOM   3978 C CA  . ALA B 2 193 ? -25.395 -2.946  -18.079 1   25.07  ? 363 ALA B CA  1 
ATOM   3979 C C   . ALA B 2 193 ? -25.571 -3.906  -19.256 1   27.25  ? 363 ALA B C   1 
ATOM   3980 O O   . ALA B 2 193 ? -25.121 -3.62   -20.372 1   28.18  ? 363 ALA B O   1 
ATOM   3981 C CB  . ALA B 2 193 ? -24.289 -3.397  -17.145 1   23.21  ? 363 ALA B CB  1 
ATOM   3982 N N   . LEU B 2 194 ? -26.248 -5.027  -18.993 1   27.21  ? 364 LEU B N   1 
ATOM   3983 C CA  . LEU B 2 194 ? -26.479 -6.067  -19.977 1   28.05  ? 364 LEU B CA  1 
ATOM   3984 C C   . LEU B 2 194 ? -27.223 -5.488  -21.167 1   29.68  ? 364 LEU B C   1 
ATOM   3985 O O   . LEU B 2 194 ? -26.833 -5.715  -22.316 1   32.8   ? 364 LEU B O   1 
ATOM   3986 C CB  . LEU B 2 194 ? -27.325 -7.152  -19.316 1   32.52  ? 364 LEU B CB  1 
ATOM   3987 C CG  . LEU B 2 194 ? -27.499 -8.46   -20.091 1   36.02  ? 364 LEU B CG  1 
ATOM   3988 C CD1 . LEU B 2 194 ? -26.158 -9.094  -20.46  1   38.85  ? 364 LEU B CD1 1 
ATOM   3989 C CD2 . LEU B 2 194 ? -28.277 -9.413  -19.207 1   40.06  ? 364 LEU B CD2 1 
ATOM   3990 N N   . TYR B 2 195 ? -28.293 -4.74   -20.87  1   27.77  ? 365 TYR B N   1 
ATOM   3991 C CA  . TYR B 2 195 ? -29.139 -4.184  -21.911 1   26.81  ? 365 TYR B CA  1 
ATOM   3992 C C   . TYR B 2 195 ? -28.362 -3.157  -22.735 1   24.93  ? 365 TYR B C   1 
ATOM   3993 O O   . TYR B 2 195 ? -28.466 -3.172  -23.939 1   23.66  ? 365 TYR B O   1 
ATOM   3994 C CB  . TYR B 2 195 ? -30.392 -3.62   -21.24  1   24.86  ? 365 TYR B CB  1 
ATOM   3995 C CG  . TYR B 2 195 ? -31.414 -3.074  -22.219 1   25.92  ? 365 TYR B CG  1 
ATOM   3996 C CD1 . TYR B 2 195 ? -32.159 -3.937  -23.024 1   27.01  ? 365 TYR B CD1 1 
ATOM   3997 C CD2 . TYR B 2 195 ? -31.631 -1.71   -22.336 1   25.22  ? 365 TYR B CD2 1 
ATOM   3998 C CE1 . TYR B 2 195 ? -33.106 -3.462  -23.918 1   26     ? 365 TYR B CE1 1 
ATOM   3999 C CE2 . TYR B 2 195 ? -32.578 -1.227  -23.22  1   27.99  ? 365 TYR B CE2 1 
ATOM   4000 C CZ  . TYR B 2 195 ? -33.31  -2.097  -24.016 1   28.4   ? 365 TYR B CZ  1 
ATOM   4001 O OH  . TYR B 2 195 ? -34.222 -1.578  -24.897 1   29.62  ? 365 TYR B OH  1 
ATOM   4002 N N   . THR B 2 196 ? -27.594 -2.278  -22.085 1   26.07  ? 366 THR B N   1 
ATOM   4003 C CA  . THR B 2 196 ? -26.881 -1.187  -22.742 1   28.5   ? 366 THR B CA  1 
ATOM   4004 C C   . THR B 2 196 ? -25.883 -1.753  -23.755 1   30.28  ? 366 THR B C   1 
ATOM   4005 O O   . THR B 2 196 ? -25.801 -1.255  -24.873 1   34.4   ? 366 THR B O   1 
ATOM   4006 C CB  . THR B 2 196 ? -26.187 -0.288  -21.707 1   29.55  ? 366 THR B CB  1 
ATOM   4007 O OG1 . THR B 2 196 ? -27.163 0.341   -20.879 1   32.59  ? 366 THR B OG1 1 
ATOM   4008 C CG2 . THR B 2 196 ? -25.32  0.806   -22.31  1   24.67  ? 366 THR B CG2 1 
ATOM   4009 N N   . VAL B 2 197 ? -25.171 -2.824  -23.38  1   30.11  ? 367 VAL B N   1 
ATOM   4010 C CA  . VAL B 2 197 ? -24.051 -3.321  -24.158 1   26.63  ? 367 VAL B CA  1 
ATOM   4011 C C   . VAL B 2 197 ? -24.523 -4.344  -25.18  1   24.78  ? 367 VAL B C   1 
ATOM   4012 O O   . VAL B 2 197 ? -24.002 -4.352  -26.302 1   23.61  ? 367 VAL B O   1 
ATOM   4013 C CB  . VAL B 2 197 ? -22.956 -3.935  -23.27  1   27.4   ? 367 VAL B CB  1 
ATOM   4014 C CG1 . VAL B 2 197 ? -21.903 -4.675  -24.103 1   23.55  ? 367 VAL B CG1 1 
ATOM   4015 C CG2 . VAL B 2 197 ? -22.324 -2.887  -22.363 1   26     ? 367 VAL B CG2 1 
ATOM   4016 N N   . THR B 2 198 ? -25.462 -5.218  -24.776 1   23.23  ? 368 THR B N   1 
ATOM   4017 C CA  . THR B 2 198 ? -25.821 -6.36   -25.609 1   23.57  ? 368 THR B CA  1 
ATOM   4018 C C   . THR B 2 198 ? -27.283 -6.354  -26.031 1   23.92  ? 368 THR B C   1 
ATOM   4019 O O   . THR B 2 198 ? -27.685 -7.231  -26.777 1   23.7   ? 368 THR B O   1 
ATOM   4020 C CB  . THR B 2 198 ? -25.523 -7.7    -24.949 1   25.22  ? 368 THR B CB  1 
ATOM   4021 O OG1 . THR B 2 198 ? -26.494 -7.891  -23.922 1   29.42  ? 368 THR B OG1 1 
ATOM   4022 C CG2 . THR B 2 198 ? -24.095 -7.83   -24.455 1   26.12  ? 368 THR B CG2 1 
ATOM   4023 N N   . GLY B 2 199 ? -28.087 -5.431  -25.501 1   27.82  ? 369 GLY B N   1 
ATOM   4024 C CA  . GLY B 2 199 ? -29.518 -5.433  -25.763 1   29.78  ? 369 GLY B CA  1 
ATOM   4025 C C   . GLY B 2 199 ? -30.24  -6.599  -25.085 1   33.6   ? 369 GLY B C   1 
ATOM   4026 O O   . GLY B 2 199 ? -31.45  -6.751  -25.232 1   35.63  ? 369 GLY B O   1 
ATOM   4027 N N   . GLN B 2 200 ? -29.512 -7.413  -24.314 1   33.25  ? 370 GLN B N   1 
ATOM   4028 C CA  . GLN B 2 200 ? -30.152 -8.553  -23.679 1   35.81  ? 370 GLN B CA  1 
ATOM   4029 C C   . GLN B 2 200 ? -30.741 -8.115  -22.344 1   33.42  ? 370 GLN B C   1 
ATOM   4030 O O   . GLN B 2 200 ? -30.423 -7.034  -21.848 1   33.44  ? 370 GLN B O   1 
ATOM   4031 C CB  . GLN B 2 200 ? -29.152 -9.685  -23.477 1   42.55  ? 370 GLN B CB  1 
ATOM   4032 C CG  . GLN B 2 200 ? -28.79  -10.435 -24.75  1   47.41  ? 370 GLN B CG  1 
ATOM   4033 C CD  . GLN B 2 200 ? -27.698 -11.444 -24.487 1   57.94  ? 370 GLN B CD  1 
ATOM   4034 O OE1 . GLN B 2 200 ? -27.956 -12.645 -24.373 1   66.68  ? 370 GLN B OE1 1 
ATOM   4035 N NE2 . GLN B 2 200 ? -26.474 -10.959 -24.323 1   60.51  ? 370 GLN B NE2 1 
ATOM   4036 N N   . SER B 2 201 ? -31.583 -8.972  -21.763 1   31.07  ? 371 SER B N   1 
ATOM   4037 C CA  . SER B 2 201 ? -32.264 -8.626  -20.524 1   29.98  ? 371 SER B CA  1 
ATOM   4038 C C   . SER B 2 201 ? -31.849 -9.574  -19.41  1   32.83  ? 371 SER B C   1 
ATOM   4039 O O   . SER B 2 201 ? -31.306 -10.638 -19.686 1   38.95  ? 371 SER B O   1 
ATOM   4040 C CB  . SER B 2 201 ? -33.751 -8.631  -20.69  1   26.78  ? 371 SER B CB  1 
ATOM   4041 O OG  . SER B 2 201 ? -34.187 -7.355  -21.12  1   30.19  ? 371 SER B OG  1 
ATOM   4042 N N   . TRP B 2 202 ? -32.134 -9.171  -18.166 1   35.41  ? 372 TRP B N   1 
ATOM   4043 C CA  . TRP B 2 202 ? -32.002 -9.976  -16.962 1   33.16  ? 372 TRP B CA  1 
ATOM   4044 C C   . TRP B 2 202 ? -32.344 -11.434 -17.263 1   31.48  ? 372 TRP B C   1 
ATOM   4045 O O   . TRP B 2 202 ? -33.461 -11.736 -17.655 1   28.2   ? 372 TRP B O   1 
ATOM   4046 C CB  . TRP B 2 202 ? -32.906 -9.373  -15.872 1   29.34  ? 372 TRP B CB  1 
ATOM   4047 C CG  . TRP B 2 202 ? -32.94  -10.072 -14.533 1   28.56  ? 372 TRP B CG  1 
ATOM   4048 C CD1 . TRP B 2 202 ? -33.995 -10.797 -14.06  1   32.96  ? 372 TRP B CD1 1 
ATOM   4049 C CD2 . TRP B 2 202 ? -31.951 -10.089 -13.48  1   27.61  ? 372 TRP B CD2 1 
ATOM   4050 N NE1 . TRP B 2 202 ? -33.738 -11.273 -12.803 1   31.73  ? 372 TRP B NE1 1 
ATOM   4051 C CE2 . TRP B 2 202 ? -32.493 -10.85  -12.419 1   30.62  ? 372 TRP B CE2 1 
ATOM   4052 C CE3 . TRP B 2 202 ? -30.671 -9.553  -13.324 1   27.12  ? 372 TRP B CE3 1 
ATOM   4053 C CZ2 . TRP B 2 202 ? -31.805 -11.09  -11.235 1   28.63  ? 372 TRP B CZ2 1 
ATOM   4054 C CZ3 . TRP B 2 202 ? -29.994 -9.773  -12.146 1   28.81  ? 372 TRP B CZ3 1 
ATOM   4055 C CH2 . TRP B 2 202 ? -30.551 -10.539 -11.124 1   31.21  ? 372 TRP B CH2 1 
ATOM   4056 N N   . PRO B 2 203 ? -31.381 -12.371 -17.103 1   30.69  ? 373 PRO B N   1 
ATOM   4057 C CA  . PRO B 2 203 ? -31.593 -13.776 -17.463 1   30.17  ? 373 PRO B CA  1 
ATOM   4058 C C   . PRO B 2 203 ? -32.564 -14.547 -16.572 1   29.37  ? 373 PRO B C   1 
ATOM   4059 O O   . PRO B 2 203 ? -32.635 -14.318 -15.352 1   28.87  ? 373 PRO B O   1 
ATOM   4060 C CB  . PRO B 2 203 ? -30.176 -14.368 -17.403 1   30.79  ? 373 PRO B CB  1 
ATOM   4061 C CG  . PRO B 2 203 ? -29.459 -13.51  -16.37  1   36.04  ? 373 PRO B CG  1 
ATOM   4062 C CD  . PRO B 2 203 ? -30.033 -12.104 -16.581 1   32.88  ? 373 PRO B CD  1 
ATOM   4063 N N   . GLU B 2 204 ? -33.286 -15.473 -17.215 1   26.26  ? 374 GLU B N   1 
ATOM   4064 C CA  . GLU B 2 204 ? -34.147 -16.435 -16.543 1   29.1   ? 374 GLU B CA  1 
ATOM   4065 C C   . GLU B 2 204 ? -33.406 -17.137 -15.398 1   29.62  ? 374 GLU B C   1 
ATOM   4066 O O   . GLU B 2 204 ? -33.981 -17.407 -14.333 1   28.77  ? 374 GLU B O   1 
ATOM   4067 C CB  . GLU B 2 204 ? -34.631 -17.422 -17.608 1   35.21  ? 374 GLU B CB  1 
ATOM   4068 C CG  . GLU B 2 204 ? -34.694 -18.887 -17.165 1   44.63  ? 374 GLU B CG  1 
ATOM   4069 C CD  . GLU B 2 204 ? -35.896 -19.244 -16.311 1   47.32  ? 374 GLU B CD  1 
ATOM   4070 O OE1 . GLU B 2 204 ? -36.768 -18.368 -16.183 1   50.99  ? 374 GLU B OE1 1 
ATOM   4071 O OE2 . GLU B 2 204 ? -35.963 -20.366 -15.786 1   44.94  ? 374 GLU B OE2 1 
ATOM   4072 N N   . SER B 2 205 ? -32.144 -17.5   -15.662 1   26.18  ? 375 SER B N   1 
ATOM   4073 C CA  . SER B 2 205 ? -31.379 -18.28  -14.719 1   24.87  ? 375 SER B CA  1 
ATOM   4074 C C   . SER B 2 205 ? -31.23  -17.507 -13.395 1   26.82  ? 375 SER B C   1 
ATOM   4075 O O   . SER B 2 205 ? -31.135 -18.107 -12.318 1   26.04  ? 375 SER B O   1 
ATOM   4076 C CB  . SER B 2 205 ? -30.07  -18.693 -15.368 1   26.88  ? 375 SER B CB  1 
ATOM   4077 O OG  . SER B 2 205 ? -29.112 -17.633 -15.448 1   29.31  ? 375 SER B OG  1 
ATOM   4078 N N   . LEU B 2 206 ? -31.246 -16.161 -13.469 1   27.37  ? 376 LEU B N   1 
ATOM   4079 C CA  . LEU B 2 206 ? -31.097 -15.306 -12.293 1   28.2   ? 376 LEU B CA  1 
ATOM   4080 C C   . LEU B 2 206 ? -32.444 -15.051 -11.619 1   27.93  ? 376 LEU B C   1 
ATOM   4081 O O   . LEU B 2 206 ? -32.503 -14.733 -10.429 1   26.01  ? 376 LEU B O   1 
ATOM   4082 C CB  . LEU B 2 206 ? -30.419 -13.992 -12.653 1   26.84  ? 376 LEU B CB  1 
ATOM   4083 C CG  . LEU B 2 206 ? -28.897 -14.092 -12.764 1   29.7   ? 376 LEU B CG  1 
ATOM   4084 C CD1 . LEU B 2 206 ? -28.317 -12.751 -13.198 1   29.25  ? 376 LEU B CD1 1 
ATOM   4085 C CD2 . LEU B 2 206 ? -28.288 -14.56  -11.46  1   26.2   ? 376 LEU B CD2 1 
ATOM   4086 N N   . VAL B 2 207 ? -33.515 -15.18  -12.4   1   25.3   ? 377 VAL B N   1 
ATOM   4087 C CA  . VAL B 2 207 ? -34.824 -15.257 -11.792 1   27.21  ? 377 VAL B CA  1 
ATOM   4088 C C   . VAL B 2 207 ? -34.873 -16.503 -10.9   1   27.45  ? 377 VAL B C   1 
ATOM   4089 O O   . VAL B 2 207 ? -35.353 -16.439 -9.779  1   27.51  ? 377 VAL B O   1 
ATOM   4090 C CB  . VAL B 2 207 ? -35.938 -15.231 -12.862 1   27.91  ? 377 VAL B CB  1 
ATOM   4091 C CG1 . VAL B 2 207 ? -37.297 -15.534 -12.25  1   23.45  ? 377 VAL B CG1 1 
ATOM   4092 C CG2 . VAL B 2 207 ? -35.956 -13.918 -13.648 1   23.71  ? 377 VAL B CG2 1 
ATOM   4093 N N   . GLN B 2 208 ? -34.364 -17.642 -11.381 1   27.83  ? 378 GLN B N   1 
ATOM   4094 C CA  . GLN B 2 208 ? -34.315 -18.854 -10.571 1   28.22  ? 378 GLN B CA  1 
ATOM   4095 C C   . GLN B 2 208 ? -33.505 -18.635 -9.287  1   28.04  ? 378 GLN B C   1 
ATOM   4096 O O   . GLN B 2 208 ? -33.943 -19.049 -8.215  1   26.42  ? 378 GLN B O   1 
ATOM   4097 C CB  . GLN B 2 208 ? -33.624 -20.019 -11.284 1   28.89  ? 378 GLN B CB  1 
ATOM   4098 C CG  . GLN B 2 208 ? -34.378 -20.621 -12.456 1   31.07  ? 378 GLN B CG  1 
ATOM   4099 C CD  . GLN B 2 208 ? -35.729 -21.159 -12.058 1   36.24  ? 378 GLN B CD  1 
ATOM   4100 O OE1 . GLN B 2 208 ? -36.741 -20.899 -12.725 1   36.44  ? 378 GLN B OE1 1 
ATOM   4101 N NE2 . GLN B 2 208 ? -35.749 -21.9   -10.956 1   38.55  ? 378 GLN B NE2 1 
ATOM   4102 N N   . LYS B 2 209 ? -32.302 -18.056 -9.424  1   25.66  ? 379 LYS B N   1 
ATOM   4103 C CA  . LYS B 2 209 ? -31.395 -17.863 -8.306  1   28.99  ? 379 LYS B CA  1 
ATOM   4104 C C   . LYS B 2 209 ? -31.977 -16.875 -7.293  1   28.42  ? 379 LYS B C   1 
ATOM   4105 O O   . LYS B 2 209 ? -31.971 -17.145 -6.095  1   28.32  ? 379 LYS B O   1 
ATOM   4106 C CB  . LYS B 2 209 ? -30.035 -17.351 -8.799  1   31.5   ? 379 LYS B CB  1 
ATOM   4107 C CG  . LYS B 2 209 ? -28.912 -17.396 -7.767  1   36.17  ? 379 LYS B CG  1 
ATOM   4108 C CD  . LYS B 2 209 ? -27.662 -16.687 -8.279  1   40.62  ? 379 LYS B CD  1 
ATOM   4109 C CE  . LYS B 2 209 ? -26.589 -16.473 -7.24   1   37.26  ? 379 LYS B CE  1 
ATOM   4110 N NZ  . LYS B 2 209 ? -25.746 -17.651 -7.078  1   39.84  ? 379 LYS B NZ  1 
ATOM   4111 N N   . THR B 2 210 ? -32.457 -15.72  -7.773  1   28.22  ? 380 THR B N   1 
ATOM   4112 C CA  . THR B 2 210 ? -32.649 -14.564 -6.902  1   29.02  ? 380 THR B CA  1 
ATOM   4113 C C   . THR B 2 210 ? -34.103 -14.434 -6.475  1   26.96  ? 380 THR B C   1 
ATOM   4114 O O   . THR B 2 210 ? -34.369 -13.811 -5.453  1   28.37  ? 380 THR B O   1 
ATOM   4115 C CB  . THR B 2 210 ? -32.228 -13.258 -7.58   1   30.85  ? 380 THR B CB  1 
ATOM   4116 O OG1 . THR B 2 210 ? -33.108 -12.997 -8.679  1   30.16  ? 380 THR B OG1 1 
ATOM   4117 C CG2 . THR B 2 210 ? -30.78  -13.293 -8.03   1   30.74  ? 380 THR B CG2 1 
ATOM   4118 N N   . GLY B 2 211 ? -35.014 -14.952 -7.301  1   23.23  ? 381 GLY B N   1 
ATOM   4119 C CA  . GLY B 2 211 ? -36.443 -14.723 -7.136  1   25.94  ? 381 GLY B CA  1 
ATOM   4120 C C   . GLY B 2 211 ? -36.896 -13.352 -7.659  1   26.78  ? 381 GLY B C   1 
ATOM   4121 O O   . GLY B 2 211 ? -38.07  -13.025 -7.558  1   25.8   ? 381 GLY B O   1 
ATOM   4122 N N   . TYR B 2 212 ? -35.972 -12.557 -8.222  1   26.47  ? 382 TYR B N   1 
ATOM   4123 C CA  . TYR B 2 212 ? -36.3   -11.236 -8.726  1   25.38  ? 382 TYR B CA  1 
ATOM   4124 C C   . TYR B 2 212 ? -36.578 -11.308 -10.226 1   26.77  ? 382 TYR B C   1 
ATOM   4125 O O   . TYR B 2 212 ? -35.996 -12.122 -10.938 1   28.63  ? 382 TYR B O   1 
ATOM   4126 C CB  . TYR B 2 212 ? -35.174 -10.223 -8.536  1   25.13  ? 382 TYR B CB  1 
ATOM   4127 C CG  . TYR B 2 212 ? -34.628 -9.995  -7.132  1   25.83  ? 382 TYR B CG  1 
ATOM   4128 C CD1 . TYR B 2 212 ? -35.46  -10.026 -6.007  1   23.22  ? 382 TYR B CD1 1 
ATOM   4129 C CD2 . TYR B 2 212 ? -33.274 -9.673  -6.959  1   22.67  ? 382 TYR B CD2 1 
ATOM   4130 C CE1 . TYR B 2 212 ? -34.934 -9.78   -4.746  1   23.84  ? 382 TYR B CE1 1 
ATOM   4131 C CE2 . TYR B 2 212 ? -32.746 -9.426  -5.704  1   23.35  ? 382 TYR B CE2 1 
ATOM   4132 C CZ  . TYR B 2 212 ? -33.58  -9.482  -4.593  1   25.66  ? 382 TYR B CZ  1 
ATOM   4133 O OH  . TYR B 2 212 ? -33.021 -9.226  -3.365  1   24.56  ? 382 TYR B OH  1 
ATOM   4134 N N   . THR B 2 213 ? -37.5   -10.45  -10.676 1   26.71  ? 383 THR B N   1 
ATOM   4135 C CA  . THR B 2 213 ? -37.892 -10.281 -12.065 1   26.72  ? 383 THR B CA  1 
ATOM   4136 C C   . THR B 2 213 ? -37.739 -8.809  -12.428 1   28.4   ? 383 THR B C   1 
ATOM   4137 O O   . THR B 2 213 ? -37.609 -7.961  -11.544 1   30.1   ? 383 THR B O   1 
ATOM   4138 C CB  . THR B 2 213 ? -39.353 -10.691 -12.255 1   26.68  ? 383 THR B CB  1 
ATOM   4139 O OG1 . THR B 2 213 ? -40.168 -9.764  -11.533 1   25.88  ? 383 THR B OG1 1 
ATOM   4140 C CG2 . THR B 2 213 ? -39.617 -12.116 -11.816 1   24.88  ? 383 THR B CG2 1 
ATOM   4141 N N   . LEU B 2 214 ? -37.825 -8.502  -13.727 1   30.53  ? 384 LEU B N   1 
ATOM   4142 C CA  . LEU B 2 214 ? -37.865 -7.112  -14.16  1   32.71  ? 384 LEU B CA  1 
ATOM   4143 C C   . LEU B 2 214 ? -38.975 -6.36   -13.435 1   30.94  ? 384 LEU B C   1 
ATOM   4144 O O   . LEU B 2 214 ? -38.823 -5.173  -13.15  1   29.99  ? 384 LEU B O   1 
ATOM   4145 C CB  . LEU B 2 214 ? -38.038 -6.98   -15.668 1   33.58  ? 384 LEU B CB  1 
ATOM   4146 C CG  . LEU B 2 214 ? -36.806 -7.288  -16.518 1   33.65  ? 384 LEU B CG  1 
ATOM   4147 C CD1 . LEU B 2 214 ? -37.188 -7.11   -17.97  1   30.03  ? 384 LEU B CD1 1 
ATOM   4148 C CD2 . LEU B 2 214 ? -35.619 -6.412  -16.135 1   35.15  ? 384 LEU B CD2 1 
ATOM   4149 N N   . GLU B 2 215 ? -40.071 -7.069  -13.137 1   32.06  ? 385 GLU B N   1 
ATOM   4150 C CA  . GLU B 2 215 ? -41.199 -6.516  -12.4   1   32.68  ? 385 GLU B CA  1 
ATOM   4151 C C   . GLU B 2 215 ? -40.764 -6.065  -11.003 1   28.75  ? 385 GLU B C   1 
ATOM   4152 O O   . GLU B 2 215 ? -40.943 -4.901  -10.654 1   26.73  ? 385 GLU B O   1 
ATOM   4153 C CB  . GLU B 2 215 ? -42.372 -7.487  -12.389 1   34.13  ? 385 GLU B CB  1 
ATOM   4154 C CG  . GLU B 2 215 ? -43.595 -6.896  -11.711 1   43.47  ? 385 GLU B CG  1 
ATOM   4155 C CD  . GLU B 2 215 ? -44.866 -7.54   -12.23  1   62.06  ? 385 GLU B CD  1 
ATOM   4156 O OE1 . GLU B 2 215 ? -45.027 -7.711  -13.466 1   68.72  ? 385 GLU B OE1 1 
ATOM   4157 O OE2 . GLU B 2 215 ? -45.722 -7.841  -11.376 1   67.38  ? 385 GLU B OE2 1 
ATOM   4158 N N   . THR B 2 216 ? -40.165 -6.969  -10.217 1   27.22  ? 386 THR B N   1 
ATOM   4159 C CA  . THR B 2 216 ? -39.712 -6.599  -8.883  1   29.72  ? 386 THR B CA  1 
ATOM   4160 C C   . THR B 2 216 ? -38.558 -5.595  -8.939  1   29.1   ? 386 THR B C   1 
ATOM   4161 O O   . THR B 2 216 ? -38.452 -4.769  -8.047  1   28.25  ? 386 THR B O   1 
ATOM   4162 C CB  . THR B 2 216 ? -39.403 -7.81   -7.999  1   33.42  ? 386 THR B CB  1 
ATOM   4163 O OG1 . THR B 2 216 ? -38.443 -8.579  -8.707  1   37.06  ? 386 THR B OG1 1 
ATOM   4164 C CG2 . THR B 2 216 ? -40.632 -8.667  -7.717  1   33.48  ? 386 THR B CG2 1 
ATOM   4165 N N   . LEU B 2 217 ? -37.727 -5.623  -9.998  1   30.35  ? 387 LEU B N   1 
ATOM   4166 C CA  . LEU B 2 217 ? -36.58  -4.723  -10.126 1   30.38  ? 387 LEU B CA  1 
ATOM   4167 C C   . LEU B 2 217 ? -36.966 -3.347  -10.678 1   30.18  ? 387 LEU B C   1 
ATOM   4168 O O   . LEU B 2 217 ? -36.165 -2.414  -10.613 1   26.39  ? 387 LEU B O   1 
ATOM   4169 C CB  . LEU B 2 217 ? -35.516 -5.375  -11.006 1   31.28  ? 387 LEU B CB  1 
ATOM   4170 C CG  . LEU B 2 217 ? -34.923 -6.688  -10.487 1   32.57  ? 387 LEU B CG  1 
ATOM   4171 C CD1 . LEU B 2 217 ? -33.921 -7.274  -11.483 1   34.98  ? 387 LEU B CD1 1 
ATOM   4172 C CD2 . LEU B 2 217 ? -34.287 -6.465  -9.13   1   28.97  ? 387 LEU B CD2 1 
ATOM   4173 N N   . LYS B 2 218 ? -38.189 -3.22   -11.213 1   29.5   ? 388 LYS B N   1 
ATOM   4174 C CA  . LYS B 2 218 ? -38.631 -2.074  -11.996 1   27.81  ? 388 LYS B CA  1 
ATOM   4175 C C   . LYS B 2 218 ? -38.383 -0.736  -11.289 1   29.13  ? 388 LYS B C   1 
ATOM   4176 O O   . LYS B 2 218 ? -37.816 0.176   -11.895 1   29.04  ? 388 LYS B O   1 
ATOM   4177 C CB  . LYS B 2 218 ? -40.085 -2.235  -12.462 1   27.69  ? 388 LYS B CB  1 
ATOM   4178 C CG  . LYS B 2 218 ? -40.596 -1.108  -13.349 1   26.72  ? 388 LYS B CG  1 
ATOM   4179 C CD  . LYS B 2 218 ? -42.047 -1.242  -13.786 1   29.83  ? 388 LYS B CD  1 
ATOM   4180 C CE  . LYS B 2 218 ? -42.477 -0.09   -14.666 1   34.34  ? 388 LYS B CE  1 
ATOM   4181 N NZ  . LYS B 2 218 ? -43.804 -0.218  -15.287 1   33.92  ? 388 LYS B NZ  1 
ATOM   4182 N N   . PRO B 2 219 ? -38.839 -0.512  -10.031 1   29.73  ? 389 PRO B N   1 
ATOM   4183 C CA  . PRO B 2 219 ? -38.579 0.769   -9.359  1   28.45  ? 389 PRO B CA  1 
ATOM   4184 C C   . PRO B 2 219 ? -37.088 1.16    -9.317  1   27.04  ? 389 PRO B C   1 
ATOM   4185 O O   . PRO B 2 219 ? -36.671 2.217   -9.799  1   23.5   ? 389 PRO B O   1 
ATOM   4186 C CB  . PRO B 2 219 ? -39.193 0.565   -7.954  1   25.74  ? 389 PRO B CB  1 
ATOM   4187 C CG  . PRO B 2 219 ? -40.205 -0.548  -8.142  1   25.22  ? 389 PRO B CG  1 
ATOM   4188 C CD  . PRO B 2 219 ? -39.6   -1.451  -9.189  1   28.27  ? 389 PRO B CD  1 
ATOM   4189 N N   . CYS B 2 220 ? -36.271 0.293   -8.729  1   24.98  ? 390 CYS B N   1 
ATOM   4190 C CA  . CYS B 2 220 ? -34.834 0.495   -8.697  1   26.25  ? 390 CYS B CA  1 
ATOM   4191 C C   . CYS B 2 220 ? -34.259 0.826   -10.083 1   27.12  ? 390 CYS B C   1 
ATOM   4192 O O   . CYS B 2 220 ? -33.513 1.783   -10.251 1   27.28  ? 390 CYS B O   1 
ATOM   4193 C CB  . CYS B 2 220 ? -34.179 -0.759  -8.15   1   27.5   ? 390 CYS B CB  1 
ATOM   4194 S SG  . CYS B 2 220 ? -32.46  -0.437  -7.723  1   32.99  ? 390 CYS B SG  1 
ATOM   4195 N N   . LEU B 2 221 ? -34.612 0.029   -11.087 1   26.23  ? 391 LEU B N   1 
ATOM   4196 C CA  . LEU B 2 221 ? -34.144 0.189   -12.448 1   26.83  ? 391 LEU B CA  1 
ATOM   4197 C C   . LEU B 2 221 ? -34.479 1.572   -13.011 1   27.25  ? 391 LEU B C   1 
ATOM   4198 O O   . LEU B 2 221 ? -33.655 2.18    -13.685 1   27.63  ? 391 LEU B O   1 
ATOM   4199 C CB  . LEU B 2 221 ? -34.85  -0.932  -13.2   1   31.56  ? 391 LEU B CB  1 
ATOM   4200 C CG  . LEU B 2 221 ? -34.246 -1.406  -14.521 1   37.79  ? 391 LEU B CG  1 
ATOM   4201 C CD1 . LEU B 2 221 ? -32.723 -1.421  -14.492 1   36.98  ? 391 LEU B CD1 1 
ATOM   4202 C CD2 . LEU B 2 221 ? -34.779 -2.834  -14.731 1   37.95  ? 391 LEU B CD2 1 
ATOM   4203 N N   . LEU B 2 222 ? -35.665 2.109   -12.715 1   27.25  ? 392 LEU B N   1 
ATOM   4204 C CA  . LEU B 2 222 ? -36.02  3.446   -13.182 1   26.91  ? 392 LEU B CA  1 
ATOM   4205 C C   . LEU B 2 222 ? -35.12  4.524   -12.565 1   28.71  ? 392 LEU B C   1 
ATOM   4206 O O   . LEU B 2 222 ? -34.739 5.476   -13.246 1   31.53  ? 392 LEU B O   1 
ATOM   4207 C CB  . LEU B 2 222 ? -37.492 3.723   -12.898 1   25.73  ? 392 LEU B CB  1 
ATOM   4208 C CG  . LEU B 2 222 ? -38.49  2.924   -13.741 1   28.46  ? 392 LEU B CG  1 
ATOM   4209 C CD1 . LEU B 2 222 ? -39.925 3.409   -13.5   1   27.04  ? 392 LEU B CD1 1 
ATOM   4210 C CD2 . LEU B 2 222 ? -38.157 3.019   -15.216 1   27.21  ? 392 LEU B CD2 1 
ATOM   4211 N N   . ASP B 2 223 ? -34.814 4.396   -11.266 1   26.22  ? 393 ASP B N   1 
ATOM   4212 C CA  . ASP B 2 223 ? -33.91  5.31    -10.59  1   27.24  ? 393 ASP B CA  1 
ATOM   4213 C C   . ASP B 2 223 ? -32.504 5.206   -11.188 1   28.45  ? 393 ASP B C   1 
ATOM   4214 O O   . ASP B 2 223 ? -31.881 6.214   -11.522 1   28.59  ? 393 ASP B O   1 
ATOM   4215 C CB  . ASP B 2 223 ? -33.905 5.1     -9.079  1   30.29  ? 393 ASP B CB  1 
ATOM   4216 C CG  . ASP B 2 223 ? -35.147 5.573   -8.318  1   31.76  ? 393 ASP B CG  1 
ATOM   4217 O OD1 . ASP B 2 223 ? -35.718 6.623   -8.705  1   28.95  ? 393 ASP B OD1 1 
ATOM   4218 O OD2 . ASP B 2 223 ? -35.523 4.898   -7.319  1   31.19  ? 393 ASP B OD2 1 
ATOM   4219 N N   . LEU B 2 224 ? -32.002 3.978   -11.335 1   27.36  ? 394 LEU B N   1 
ATOM   4220 C CA  . LEU B 2 224 ? -30.649 3.756   -11.819 1   28.04  ? 394 LEU B CA  1 
ATOM   4221 C C   . LEU B 2 224 ? -30.515 4.271   -13.254 1   31.3   ? 394 LEU B C   1 
ATOM   4222 O O   . LEU B 2 224 ? -29.497 4.846   -13.623 1   32.88  ? 394 LEU B O   1 
ATOM   4223 C CB  . LEU B 2 224 ? -30.331 2.268   -11.707 1   27.32  ? 394 LEU B CB  1 
ATOM   4224 C CG  . LEU B 2 224 ? -28.842 1.922   -11.608 1   28.34  ? 394 LEU B CG  1 
ATOM   4225 C CD1 . LEU B 2 224 ? -28.181 2.595   -10.416 1   26.84  ? 394 LEU B CD1 1 
ATOM   4226 C CD2 . LEU B 2 224 ? -28.618 0.426   -11.564 1   25.11  ? 394 LEU B CD2 1 
ATOM   4227 N N   . HIS B 2 225 ? -31.581 4.114   -14.047 1   29.36  ? 395 HIS B N   1 
ATOM   4228 C CA  . HIS B 2 225 ? -31.609 4.619   -15.401 1   27.68  ? 395 HIS B CA  1 
ATOM   4229 C C   . HIS B 2 225 ? -31.566 6.152   -15.405 1   29.53  ? 395 HIS B C   1 
ATOM   4230 O O   . HIS B 2 225 ? -30.942 6.718   -16.292 1   30.57  ? 395 HIS B O   1 
ATOM   4231 C CB  . HIS B 2 225 ? -32.792 3.996   -16.139 1   26.31  ? 395 HIS B CB  1 
ATOM   4232 C CG  . HIS B 2 225 ? -32.951 4.465   -17.537 1   29.18  ? 395 HIS B CG  1 
ATOM   4233 N ND1 . HIS B 2 225 ? -31.909 4.373   -18.429 1   31.53  ? 395 HIS B ND1 1 
ATOM   4234 C CD2 . HIS B 2 225 ? -33.999 4.974   -18.227 1   30.75  ? 395 HIS B CD2 1 
ATOM   4235 C CE1 . HIS B 2 225 ? -32.311 4.828   -19.614 1   32.26  ? 395 HIS B CE1 1 
ATOM   4236 N NE2 . HIS B 2 225 ? -33.578 5.191   -19.518 1   31.5   ? 395 HIS B NE2 1 
ATOM   4237 N N   . GLN B 2 226 ? -32.214 6.835   -14.444 1   29.09  ? 396 GLN B N   1 
ATOM   4238 C CA  . GLN B 2 226 ? -32.11  8.288   -14.35  1   31.61  ? 396 GLN B CA  1 
ATOM   4239 C C   . GLN B 2 226 ? -30.683 8.685   -13.957 1   33.15  ? 396 GLN B C   1 
ATOM   4240 O O   . GLN B 2 226 ? -30.077 9.58    -14.554 1   34.94  ? 396 GLN B O   1 
ATOM   4241 C CB  . GLN B 2 226 ? -33.086 8.96    -13.374 1   35.2   ? 396 GLN B CB  1 
ATOM   4242 C CG  . GLN B 2 226 ? -34.474 9.331   -13.908 1   42.89  ? 396 GLN B CG  1 
ATOM   4243 C CD  . GLN B 2 226 ? -34.554 9.732   -15.376 1   53.21  ? 396 GLN B CD  1 
ATOM   4244 O OE1 . GLN B 2 226 ? -34.955 8.937   -16.24  1   45.97  ? 396 GLN B OE1 1 
ATOM   4245 N NE2 . GLN B 2 226 ? -34.181 10.968  -15.694 1   54.67  ? 396 GLN B NE2 1 
ATOM   4246 N N   . THR B 2 227 ? -30.157 8.009   -12.927 1   30.44  ? 397 THR B N   1 
ATOM   4247 C CA  . THR B 2 227 ? -28.851 8.319   -12.378 1   29.17  ? 397 THR B CA  1 
ATOM   4248 C C   . THR B 2 227 ? -27.822 8.224   -13.502 1   29.31  ? 397 THR B C   1 
ATOM   4249 O O   . THR B 2 227 ? -26.968 9.088   -13.624 1   33.55  ? 397 THR B O   1 
ATOM   4250 C CB  . THR B 2 227 ? -28.56  7.396   -11.19  1   28.68  ? 397 THR B CB  1 
ATOM   4251 O OG1 . THR B 2 227 ? -29.436 7.787   -10.133 1   27.64  ? 397 THR B OG1 1 
ATOM   4252 C CG2 . THR B 2 227 ? -27.118 7.466   -10.717 1   26.38  ? 397 THR B CG2 1 
ATOM   4253 N N   . TYR B 2 228 ? -27.952 7.194   -14.342 1   28.74  ? 398 TYR B N   1 
ATOM   4254 C CA  . TYR B 2 228 ? -27.08  6.958   -15.481 1   29.12  ? 398 TYR B CA  1 
ATOM   4255 C C   . TYR B 2 228 ? -27.212 8.092   -16.501 1   31.76  ? 398 TYR B C   1 
ATOM   4256 O O   . TYR B 2 228 ? -26.202 8.626   -16.949 1   36.51  ? 398 TYR B O   1 
ATOM   4257 C CB  . TYR B 2 228 ? -27.387 5.576   -16.061 1   27.25  ? 398 TYR B CB  1 
ATOM   4258 C CG  . TYR B 2 228 ? -26.387 5.056   -17.08  1   29.54  ? 398 TYR B CG  1 
ATOM   4259 C CD1 . TYR B 2 228 ? -25.14  5.655   -17.289 1   31.26  ? 398 TYR B CD1 1 
ATOM   4260 C CD2 . TYR B 2 228 ? -26.686 3.927   -17.826 1   29.8   ? 398 TYR B CD2 1 
ATOM   4261 C CE1 . TYR B 2 228 ? -24.23  5.143   -18.208 1   29.96  ? 398 TYR B CE1 1 
ATOM   4262 C CE2 . TYR B 2 228 ? -25.786 3.413   -18.744 1   30.06  ? 398 TYR B CE2 1 
ATOM   4263 C CZ  . TYR B 2 228 ? -24.555 4.015   -18.945 1   31.71  ? 398 TYR B CZ  1 
ATOM   4264 O OH  . TYR B 2 228 ? -23.722 3.45    -19.884 1   34.48  ? 398 TYR B OH  1 
ATOM   4265 N N   . LEU B 2 229 ? -28.445 8.488   -16.847 1   28.84  ? 399 LEU B N   1 
ATOM   4266 C CA  . LEU B 2 229 ? -28.662 9.529   -17.839 1   27.17  ? 399 LEU B CA  1 
ATOM   4267 C C   . LEU B 2 229 ? -28.092 10.866  -17.369 1   27.11  ? 399 LEU B C   1 
ATOM   4268 O O   . LEU B 2 229 ? -27.544 11.605  -18.179 1   25.31  ? 399 LEU B O   1 
ATOM   4269 C CB  . LEU B 2 229 ? -30.145 9.639   -18.181 1   27.32  ? 399 LEU B CB  1 
ATOM   4270 C CG  . LEU B 2 229 ? -30.681 8.61    -19.182 1   27.74  ? 399 LEU B CG  1 
ATOM   4271 C CD1 . LEU B 2 229 ? -32.191 8.66    -19.186 1   27.17  ? 399 LEU B CD1 1 
ATOM   4272 C CD2 . LEU B 2 229 ? -30.17  8.878   -20.59  1   29.81  ? 399 LEU B CD2 1 
ATOM   4273 N N   . ARG B 2 230 ? -28.207 11.161  -16.064 1   28.71  ? 400 ARG B N   1 
ATOM   4274 C CA  . ARG B 2 230 ? -27.789 12.445  -15.512 1   32.06  ? 400 ARG B CA  1 
ATOM   4275 C C   . ARG B 2 230 ? -26.319 12.416  -15.09  1   29.72  ? 400 ARG B C   1 
ATOM   4276 O O   . ARG B 2 230 ? -25.808 13.404  -14.572 1   28.59  ? 400 ARG B O   1 
ATOM   4277 C CB  . ARG B 2 230 ? -28.622 12.845  -14.281 1   35.64  ? 400 ARG B CB  1 
ATOM   4278 C CG  . ARG B 2 230 ? -29.998 13.415  -14.599 1   47.86  ? 400 ARG B CG  1 
ATOM   4279 C CD  . ARG B 2 230 ? -31.01  13.285  -13.476 1   59.03  ? 400 ARG B CD  1 
ATOM   4280 N NE  . ARG B 2 230 ? -32.406 13.403  -13.924 1   67.97  ? 400 ARG B NE  1 
ATOM   4281 C CZ  . ARG B 2 230 ? -33.519 13.095  -13.236 1   74.11  ? 400 ARG B CZ  1 
ATOM   4282 N NH1 . ARG B 2 230 ? -33.475 12.464  -12.065 1   66.92  ? 400 ARG B NH1 1 
ATOM   4283 N NH2 . ARG B 2 230 ? -34.697 13.393  -13.759 1   65.53  ? 400 ARG B NH2 1 
ATOM   4284 N N   . ALA B 2 231 ? -25.635 11.284  -15.261 1   26.24  ? 401 ALA B N   1 
ATOM   4285 C CA  . ALA B 2 231 ? -24.361 11.143  -14.568 1   29.27  ? 401 ALA B CA  1 
ATOM   4286 C C   . ALA B 2 231 ? -23.363 12.246  -14.977 1   28.86  ? 401 ALA B C   1 
ATOM   4287 O O   . ALA B 2 231 ? -22.619 12.761  -14.146 1   29.29  ? 401 ALA B O   1 
ATOM   4288 C CB  . ALA B 2 231 ? -23.839 9.725   -14.725 1   27.64  ? 401 ALA B CB  1 
ATOM   4289 N N   . PRO B 2 232 ? -23.292 12.666  -16.26  1   27.67  ? 402 PRO B N   1 
ATOM   4290 C CA  . PRO B 2 232 ? -22.397 13.761  -16.639 1   28.74  ? 402 PRO B CA  1 
ATOM   4291 C C   . PRO B 2 232 ? -22.68  15.105  -15.976 1   30.57  ? 402 PRO B C   1 
ATOM   4292 O O   . PRO B 2 232 ? -21.817 15.969  -15.976 1   32.47  ? 402 PRO B O   1 
ATOM   4293 C CB  . PRO B 2 232 ? -22.567 13.852  -18.162 1   25.54  ? 402 PRO B CB  1 
ATOM   4294 C CG  . PRO B 2 232 ? -23.099 12.493  -18.565 1   25.42  ? 402 PRO B CG  1 
ATOM   4295 C CD  . PRO B 2 232 ? -23.97  12.05   -17.417 1   26.5   ? 402 PRO B CD  1 
ATOM   4296 N N   . GLN B 2 233 ? -23.889 15.282  -15.437 1   32.21  ? 403 GLN B N   1 
ATOM   4297 C CA  . GLN B 2 233 ? -24.315 16.549  -14.858 1   32.54  ? 403 GLN B CA  1 
ATOM   4298 C C   . GLN B 2 233 ? -24.245 16.524  -13.33  1   31.43  ? 403 GLN B C   1 
ATOM   4299 O O   . GLN B 2 233 ? -24.452 17.557  -12.707 1   32.36  ? 403 GLN B O   1 
ATOM   4300 C CB  . GLN B 2 233 ? -25.764 16.873  -15.23  1   34.74  ? 403 GLN B CB  1 
ATOM   4301 C CG  . GLN B 2 233 ? -25.965 17.399  -16.646 1   47.6   ? 403 GLN B CG  1 
ATOM   4302 C CD  . GLN B 2 233 ? -25.991 16.322  -17.709 1   55.25  ? 403 GLN B CD  1 
ATOM   4303 O OE1 . GLN B 2 233 ? -25.222 16.377  -18.682 1   53.63  ? 403 GLN B OE1 1 
ATOM   4304 N NE2 . GLN B 2 233 ? -26.88  15.343  -17.537 1   56.66  ? 403 GLN B NE2 1 
ATOM   4305 N N   . HIS B 2 234 ? -24.005 15.354  -12.721 1   31.99  ? 404 HIS B N   1 
ATOM   4306 C CA  . HIS B 2 234 ? -23.995 15.254  -11.264 1   32.57  ? 404 HIS B CA  1 
ATOM   4307 C C   . HIS B 2 234 ? -22.853 16.119  -10.743 1   29.91  ? 404 HIS B C   1 
ATOM   4308 O O   . HIS B 2 234 ? -21.836 16.273  -11.411 1   30.18  ? 404 HIS B O   1 
ATOM   4309 C CB  . HIS B 2 234 ? -23.834 13.798  -10.806 1   31.43  ? 404 HIS B CB  1 
ATOM   4310 C CG  . HIS B 2 234 ? -24.245 13.493  -9.398  1   33.34  ? 404 HIS B CG  1 
ATOM   4311 N ND1 . HIS B 2 234 ? -23.488 13.819  -8.29   1   32.91  ? 404 HIS B ND1 1 
ATOM   4312 C CD2 . HIS B 2 234 ? -25.321 12.829  -8.919  1   33.15  ? 404 HIS B CD2 1 
ATOM   4313 C CE1 . HIS B 2 234 ? -24.093 13.386  -7.185  1   30.65  ? 404 HIS B CE1 1 
ATOM   4314 N NE2 . HIS B 2 234 ? -25.197 12.773  -7.545  1   33.14  ? 404 HIS B NE2 1 
ATOM   4315 N N   . ALA B 2 235 ? -23.048 16.713  -9.567  1   28.4   ? 405 ALA B N   1 
ATOM   4316 C CA  . ALA B 2 235 ? -22.02  17.528  -8.943  1   27.78  ? 405 ALA B CA  1 
ATOM   4317 C C   . ALA B 2 235 ? -20.741 16.711  -8.706  1   27.75  ? 405 ALA B C   1 
ATOM   4318 O O   . ALA B 2 235 ? -19.645 17.261  -8.708  1   27.56  ? 405 ALA B O   1 
ATOM   4319 C CB  . ALA B 2 235 ? -22.586 18.09   -7.658  1   24.05  ? 405 ALA B CB  1 
ATOM   4320 N N   . GLN B 2 236 ? -20.89  15.399  -8.484  1   26.94  ? 406 GLN B N   1 
ATOM   4321 C CA  . GLN B 2 236 ? -19.801 14.503  -8.138  1   29.66  ? 406 GLN B CA  1 
ATOM   4322 C C   . GLN B 2 236 ? -19.427 13.659  -9.348  1   30.38  ? 406 GLN B C   1 
ATOM   4323 O O   . GLN B 2 236 ? -20.288 13.015  -9.947  1   31.93  ? 406 GLN B O   1 
ATOM   4324 C CB  . GLN B 2 236 ? -20.222 13.575  -6.997  1   31.05  ? 406 GLN B CB  1 
ATOM   4325 C CG  . GLN B 2 236 ? -19.996 14.168  -5.613  1   32.63  ? 406 GLN B CG  1 
ATOM   4326 C CD  . GLN B 2 236 ? -20.885 15.358  -5.32   1   35.72  ? 406 GLN B CD  1 
ATOM   4327 O OE1 . GLN B 2 236 ? -22.11  15.293  -5.467  1   41.37  ? 406 GLN B OE1 1 
ATOM   4328 N NE2 . GLN B 2 236 ? -20.282 16.462  -4.903  1   31.89  ? 406 GLN B NE2 1 
ATOM   4329 N N   . GLN B 2 237 ? -18.126 13.637  -9.665  1   28.52  ? 407 GLN B N   1 
ATOM   4330 C CA  . GLN B 2 237 ? -17.644 13.157  -10.955 1   26.13  ? 407 GLN B CA  1 
ATOM   4331 C C   . GLN B 2 237 ? -16.54  12.105  -10.812 1   26.64  ? 407 GLN B C   1 
ATOM   4332 O O   . GLN B 2 237 ? -16.103 11.541  -11.81  1   28.53  ? 407 GLN B O   1 
ATOM   4333 C CB  . GLN B 2 237 ? -17.195 14.328  -11.83  1   22.45  ? 407 GLN B CB  1 
ATOM   4334 C CG  . GLN B 2 237 ? -18.331 15.194  -12.374 1   21.8   ? 407 GLN B CG  1 
ATOM   4335 C CD  . GLN B 2 237 ? -19.249 14.442  -13.314 1   23.39  ? 407 GLN B CD  1 
ATOM   4336 O OE1 . GLN B 2 237 ? -18.789 13.599  -14.082 1   26.93  ? 407 GLN B OE1 1 
ATOM   4337 N NE2 . GLN B 2 237 ? -20.55  14.695  -13.257 1   22.66  ? 407 GLN B NE2 1 
ATOM   4338 N N   . SER B 2 238 ? -16.145 11.772  -9.584  1   26.68  ? 408 SER B N   1 
ATOM   4339 C CA  . SER B 2 238 ? -14.952 10.962  -9.4    1   30.65  ? 408 SER B CA  1 
ATOM   4340 C C   . SER B 2 238 ? -15.151 9.535   -9.926  1   31.86  ? 408 SER B C   1 
ATOM   4341 O O   . SER B 2 238 ? -14.183 8.902   -10.356 1   29.77  ? 408 SER B O   1 
ATOM   4342 C CB  . SER B 2 238 ? -14.483 10.985  -7.953  1   28.73  ? 408 SER B CB  1 
ATOM   4343 O OG  . SER B 2 238 ? -14.099 12.301  -7.582  1   27.28  ? 408 SER B OG  1 
ATOM   4344 N N   . ILE B 2 239 ? -16.394 9.035   -9.893  1   26.68  ? 409 ILE B N   1 
ATOM   4345 C CA  . ILE B 2 239 ? -16.667 7.699   -10.4   1   27.27  ? 409 ILE B CA  1 
ATOM   4346 C C   . ILE B 2 239 ? -16.59  7.687   -11.932 1   27.19  ? 409 ILE B C   1 
ATOM   4347 O O   . ILE B 2 239 ? -15.997 6.789   -12.535 1   27.34  ? 409 ILE B O   1 
ATOM   4348 C CB  . ILE B 2 239 ? -18.013 7.169   -9.873  1   27.14  ? 409 ILE B CB  1 
ATOM   4349 C CG1 . ILE B 2 239 ? -17.952 6.922   -8.394  1   25.82  ? 409 ILE B CG1 1 
ATOM   4350 C CG2 . ILE B 2 239 ? -18.439 5.908   -10.623 1   28.5   ? 409 ILE B CG2 1 
ATOM   4351 C CD1 . ILE B 2 239 ? -19.304 6.709   -7.765  1   25.12  ? 409 ILE B CD1 1 
ATOM   4352 N N   . ARG B 2 240 ? -17.163 8.709   -12.564 1   25.62  ? 410 ARG B N   1 
ATOM   4353 C CA  . ARG B 2 240 ? -17.057 8.84    -14.005 1   26.85  ? 410 ARG B CA  1 
ATOM   4354 C C   . ARG B 2 240 ? -15.592 8.877   -14.444 1   26.14  ? 410 ARG B C   1 
ATOM   4355 O O   . ARG B 2 240 ? -15.24  8.164   -15.382 1   24.65  ? 410 ARG B O   1 
ATOM   4356 C CB  . ARG B 2 240 ? -17.85  10.047  -14.507 1   27.46  ? 410 ARG B CB  1 
ATOM   4357 C CG  . ARG B 2 240 ? -19.351 9.797   -14.52  1   32.62  ? 410 ARG B CG  1 
ATOM   4358 C CD  . ARG B 2 240 ? -20.182 10.877  -15.226 1   32.69  ? 410 ARG B CD  1 
ATOM   4359 N NE  . ARG B 2 240 ? -20.005 10.794  -16.677 1   28.09  ? 410 ARG B NE  1 
ATOM   4360 C CZ  . ARG B 2 240 ? -19.425 11.689  -17.446 1   26.86  ? 410 ARG B CZ  1 
ATOM   4361 N NH1 . ARG B 2 240 ? -19.303 11.421  -18.723 1   23.85  ? 410 ARG B NH1 1 
ATOM   4362 N NH2 . ARG B 2 240 ? -18.95  12.815  -16.944 1   27.35  ? 410 ARG B NH2 1 
ATOM   4363 N N   . GLU B 2 241 ? -14.773 9.733   -13.801 1   27.61  ? 411 GLU B N   1 
ATOM   4364 C CA  . GLU B 2 241 ? -13.35  9.858   -14.11  1   30.53  ? 411 GLU B CA  1 
ATOM   4365 C C   . GLU B 2 241 ? -12.676 8.497   -13.943 1   30.96  ? 411 GLU B C   1 
ATOM   4366 O O   . GLU B 2 241 ? -11.935 8.051   -14.807 1   32.46  ? 411 GLU B O   1 
ATOM   4367 C CB  . GLU B 2 241 ? -12.558 10.806  -13.204 1   34.33  ? 411 GLU B CB  1 
ATOM   4368 C CG  . GLU B 2 241 ? -13.099 12.232  -13.087 1   38.3   ? 411 GLU B CG  1 
ATOM   4369 C CD  . GLU B 2 241 ? -13.106 13.076  -14.351 1   44.96  ? 411 GLU B CD  1 
ATOM   4370 O OE1 . GLU B 2 241 ? -12.338 12.799  -15.313 1   40.39  ? 411 GLU B OE1 1 
ATOM   4371 O OE2 . GLU B 2 241 ? -13.926 14.027  -14.355 1   49.01  ? 411 GLU B OE2 1 
ATOM   4372 N N   . LYS B 2 242 ? -12.93  7.847   -12.81  1   32.76  ? 412 LYS B N   1 
ATOM   4373 C CA  . LYS B 2 242 ? -12.351 6.546   -12.534 1   31.67  ? 412 LYS B CA  1 
ATOM   4374 C C   . LYS B 2 242 ? -12.713 5.572   -13.66  1   31.65  ? 412 LYS B C   1 
ATOM   4375 O O   . LYS B 2 242 ? -11.833 4.875   -14.15  1   32.61  ? 412 LYS B O   1 
ATOM   4376 C CB  . LYS B 2 242 ? -12.738 6.095   -11.116 1   25.91  ? 412 LYS B CB  1 
ATOM   4377 C CG  . LYS B 2 242 ? -12.608 4.614   -10.8   1   24.32  ? 412 LYS B CG  1 
ATOM   4378 C CD  . LYS B 2 242 ? -13.084 4.313   -9.379  1   25.97  ? 412 LYS B CD  1 
ATOM   4379 C CE  . LYS B 2 242 ? -13.176 2.852   -9.024  1   24.92  ? 412 LYS B CE  1 
ATOM   4380 N NZ  . LYS B 2 242 ? -13.725 2.594   -7.694  1   25.1   ? 412 LYS B NZ  1 
ATOM   4381 N N   . TYR B 2 243 ? -13.989 5.521   -14.066 1   26.53  ? 413 TYR B N   1 
ATOM   4382 C CA  . TYR B 2 243 ? -14.403 4.507   -15.022 1   25.75  ? 413 TYR B CA  1 
ATOM   4383 C C   . TYR B 2 243 ? -14.102 4.926   -16.468 1   26.24  ? 413 TYR B C   1 
ATOM   4384 O O   . TYR B 2 243 ? -14.521 4.218   -17.38  1   28.75  ? 413 TYR B O   1 
ATOM   4385 C CB  . TYR B 2 243 ? -15.839 4.028   -14.763 1   23.75  ? 413 TYR B CB  1 
ATOM   4386 C CG  . TYR B 2 243 ? -15.947 3.018   -13.634 1   24.04  ? 413 TYR B CG  1 
ATOM   4387 C CD1 . TYR B 2 243 ? -15.951 3.452   -12.313 1   26.11  ? 413 TYR B CD1 1 
ATOM   4388 C CD2 . TYR B 2 243 ? -16.032 1.65    -13.875 1   23.85  ? 413 TYR B CD2 1 
ATOM   4389 C CE1 . TYR B 2 243 ? -16.051 2.575   -11.25  1   25.13  ? 413 TYR B CE1 1 
ATOM   4390 C CE2 . TYR B 2 243 ? -16.123 0.759   -12.816 1   28.09  ? 413 TYR B CE2 1 
ATOM   4391 C CZ  . TYR B 2 243 ? -16.119 1.222   -11.505 1   27.32  ? 413 TYR B CZ  1 
ATOM   4392 O OH  . TYR B 2 243 ? -16.155 0.403   -10.417 1   26.38  ? 413 TYR B OH  1 
ATOM   4393 N N   . LYS B 2 244 ? -13.368 6.034   -16.689 1   25.6   ? 414 LYS B N   1 
ATOM   4394 C CA  . LYS B 2 244 ? -12.742 6.334   -17.981 1   28.83  ? 414 LYS B CA  1 
ATOM   4395 C C   . LYS B 2 244 ? -11.487 5.476   -18.216 1   29.3   ? 414 LYS B C   1 
ATOM   4396 O O   . LYS B 2 244 ? -11.071 5.243   -19.357 1   30.12  ? 414 LYS B O   1 
ATOM   4397 C CB  . LYS B 2 244 ? -12.307 7.799   -18.11  1   29.89  ? 414 LYS B CB  1 
ATOM   4398 C CG  . LYS B 2 244 ? -13.41  8.833   -18.21  1   30.3   ? 414 LYS B CG  1 
ATOM   4399 C CD  . LYS B 2 244 ? -12.914 10.276  -18.151 1   33.55  ? 414 LYS B CD  1 
ATOM   4400 C CE  . LYS B 2 244 ? -14.099 11.21   -18.228 1   40.59  ? 414 LYS B CE  1 
ATOM   4401 N NZ  . LYS B 2 244 ? -13.723 12.624  -18.158 1   41.91  ? 414 LYS B NZ  1 
ATOM   4402 N N   . ASN B 2 245 ? -10.876 5.02    -17.119 1   28.38  ? 415 ASN B N   1 
ATOM   4403 C CA  . ASN B 2 245 ? -9.63   4.278   -17.135 1   30.65  ? 415 ASN B CA  1 
ATOM   4404 C C   . ASN B 2 245 ? -9.834  2.915   -17.794 1   30.2   ? 415 ASN B C   1 
ATOM   4405 O O   . ASN B 2 245 ? -10.902 2.318   -17.685 1   30.86  ? 415 ASN B O   1 
ATOM   4406 C CB  . ASN B 2 245 ? -9.063  4.229   -15.723 1   37.82  ? 415 ASN B CB  1 
ATOM   4407 C CG  . ASN B 2 245 ? -7.668  3.657   -15.627 1   47.84  ? 415 ASN B CG  1 
ATOM   4408 O OD1 . ASN B 2 245 ? -7.494  2.436   -15.71  1   52.4   ? 415 ASN B OD1 1 
ATOM   4409 N ND2 . ASN B 2 245 ? -6.678  4.514   -15.402 1   46.56  ? 415 ASN B ND2 1 
ATOM   4410 N N   . SER B 2 246 ? -8.784  2.428   -18.466 1   29.04  ? 416 SER B N   1 
ATOM   4411 C CA  . SER B 2 246 ? -8.87   1.229   -19.283 1   29.89  ? 416 SER B CA  1 
ATOM   4412 C C   . SER B 2 246 ? -8.936  -0.041  -18.429 1   30.37  ? 416 SER B C   1 
ATOM   4413 O O   . SER B 2 246 ? -9.397  -1.08   -18.887 1   31.83  ? 416 SER B O   1 
ATOM   4414 C CB  . SER B 2 246 ? -7.766  1.178   -20.29  1   28.26  ? 416 SER B CB  1 
ATOM   4415 O OG  . SER B 2 246 ? -6.562  0.906   -19.599 1   34.01  ? 416 SER B OG  1 
ATOM   4416 N N   . LYS B 2 247 ? -8.49   0.054   -17.177 1   32.57  ? 417 LYS B N   1 
ATOM   4417 C CA  . LYS B 2 247 ? -8.679  -0.992  -16.185 1   36.36  ? 417 LYS B CA  1 
ATOM   4418 C C   . LYS B 2 247 ? -10.153 -1.391  -16.093 1   38.24  ? 417 LYS B C   1 
ATOM   4419 O O   . LYS B 2 247 ? -10.466 -2.55   -15.837 1   39.91  ? 417 LYS B O   1 
ATOM   4420 C CB  . LYS B 2 247 ? -8.259  -0.38   -14.848 1   37.22  ? 417 LYS B CB  1 
ATOM   4421 C CG  . LYS B 2 247 ? -8.363  -1.199  -13.581 1   39.72  ? 417 LYS B CG  1 
ATOM   4422 C CD  . LYS B 2 247 ? -7.968  -0.27   -12.425 1   49.62  ? 417 LYS B CD  1 
ATOM   4423 C CE  . LYS B 2 247 ? -7.316  -0.883  -11.211 1   51.13  ? 417 LYS B CE  1 
ATOM   4424 N NZ  . LYS B 2 247 ? -8.012  -2.118  -10.858 1   43.88  ? 417 LYS B NZ  1 
ATOM   4425 N N   . TYR B 2 248 ? -11.054 -0.422  -16.301 1   36.65  ? 418 TYR B N   1 
ATOM   4426 C CA  . TYR B 2 248 ? -12.487 -0.67   -16.242 1   35.17  ? 418 TYR B CA  1 
ATOM   4427 C C   . TYR B 2 248 ? -13.097 -0.563  -17.637 1   33.28  ? 418 TYR B C   1 
ATOM   4428 O O   . TYR B 2 248 ? -14.311 -0.414  -17.777 1   34.08  ? 418 TYR B O   1 
ATOM   4429 C CB  . TYR B 2 248 ? -13.154 0.304   -15.263 1   38.18  ? 418 TYR B CB  1 
ATOM   4430 C CG  . TYR B 2 248 ? -12.502 0.364   -13.89  1   36.76  ? 418 TYR B CG  1 
ATOM   4431 C CD1 . TYR B 2 248 ? -12.62  -0.687  -12.988 1   38.92  ? 418 TYR B CD1 1 
ATOM   4432 C CD2 . TYR B 2 248 ? -11.769 1.474   -13.506 1   35.32  ? 418 TYR B CD2 1 
ATOM   4433 C CE1 . TYR B 2 248 ? -12.021 -0.637  -11.738 1   39.59  ? 418 TYR B CE1 1 
ATOM   4434 C CE2 . TYR B 2 248 ? -11.156 1.53    -12.267 1   38.85  ? 418 TYR B CE2 1 
ATOM   4435 C CZ  . TYR B 2 248 ? -11.277 0.475   -11.372 1   41.54  ? 418 TYR B CZ  1 
ATOM   4436 O OH  . TYR B 2 248 ? -10.656 0.569   -10.141 1   46.12  ? 418 TYR B OH  1 
ATOM   4437 N N   . HIS B 2 249 ? -12.226 -0.609  -18.652 1   29.39  ? 419 HIS B N   1 
ATOM   4438 C CA  . HIS B 2 249 ? -12.613 -0.718  -20.047 1   28.16  ? 419 HIS B CA  1 
ATOM   4439 C C   . HIS B 2 249 ? -13.303 0.56    -20.521 1   28.05  ? 419 HIS B C   1 
ATOM   4440 O O   . HIS B 2 249 ? -14.075 0.522   -21.475 1   26.77  ? 419 HIS B O   1 
ATOM   4441 C CB  . HIS B 2 249 ? -13.47  -1.97   -20.271 1   31.38  ? 419 HIS B CB  1 
ATOM   4442 C CG  . HIS B 2 249 ? -12.851 -3.267  -19.833 1   37.09  ? 419 HIS B CG  1 
ATOM   4443 N ND1 . HIS B 2 249 ? -13.073 -3.742  -18.552 1   39.9   ? 419 HIS B ND1 1 
ATOM   4444 C CD2 . HIS B 2 249 ? -12.08  -4.198  -20.456 1   34.06  ? 419 HIS B CD2 1 
ATOM   4445 C CE1 . HIS B 2 249 ? -12.437 -4.911  -18.404 1   41.27  ? 419 HIS B CE1 1 
ATOM   4446 N NE2 . HIS B 2 249 ? -11.826 -5.2    -19.546 1   36.76  ? 419 HIS B NE2 1 
ATOM   4447 N N   . GLY B 2 250 ? -13.022 1.693   -19.859 1   28.12  ? 420 GLY B N   1 
ATOM   4448 C CA  . GLY B 2 250 ? -13.509 2.99    -20.319 1   27.44  ? 420 GLY B CA  1 
ATOM   4449 C C   . GLY B 2 250 ? -15.037 3.068   -20.357 1   29.97  ? 420 GLY B C   1 
ATOM   4450 O O   . GLY B 2 250 ? -15.588 3.895   -21.1   1   31.04  ? 420 GLY B O   1 
ATOM   4451 N N   . VAL B 2 251 ? -15.703 2.242   -19.524 1   24.48  ? 421 VAL B N   1 
ATOM   4452 C CA  . VAL B 2 251 ? -17.143 2.057   -19.619 1   23.87  ? 421 VAL B CA  1 
ATOM   4453 C C   . VAL B 2 251 ? -17.903 3.355   -19.349 1   25.87  ? 421 VAL B C   1 
ATOM   4454 O O   . VAL B 2 251 ? -18.994 3.526   -19.881 1   30.14  ? 421 VAL B O   1 
ATOM   4455 C CB  . VAL B 2 251 ? -17.706 0.915   -18.77  1   22.03  ? 421 VAL B CB  1 
ATOM   4456 C CG1 . VAL B 2 251 ? -17.251 -0.432  -19.316 1   22.1   ? 421 VAL B CG1 1 
ATOM   4457 C CG2 . VAL B 2 251 ? -17.343 1.08    -17.297 1   24.64  ? 421 VAL B CG2 1 
ATOM   4458 N N   . SER B 2 252 ? -17.332 4.288   -18.578 1   24.17  ? 422 SER B N   1 
ATOM   4459 C CA  . SER B 2 252 ? -18.044 5.525   -18.291 1   23.67  ? 422 SER B CA  1 
ATOM   4460 C C   . SER B 2 252 ? -18.229 6.364   -19.547 1   24.81  ? 422 SER B C   1 
ATOM   4461 O O   . SER B 2 252 ? -18.983 7.326   -19.514 1   26.11  ? 422 SER B O   1 
ATOM   4462 C CB  . SER B 2 252 ? -17.461 6.329   -17.146 1   22.27  ? 422 SER B CB  1 
ATOM   4463 O OG  . SER B 2 252 ? -16.251 6.956   -17.491 1   22.58  ? 422 SER B OG  1 
ATOM   4464 N N   . LEU B 2 253 ? -17.581 5.972   -20.651 1   27.15  ? 423 LEU B N   1 
ATOM   4465 C CA  . LEU B 2 253 ? -17.686 6.692   -21.914 1   25.31  ? 423 LEU B CA  1 
ATOM   4466 C C   . LEU B 2 253 ? -18.772 6.092   -22.812 1   25.57  ? 423 LEU B C   1 
ATOM   4467 O O   . LEU B 2 253 ? -19.166 6.717   -23.792 1   23.69  ? 423 LEU B O   1 
ATOM   4468 C CB  . LEU B 2 253 ? -16.323 6.73    -22.607 1   26.17  ? 423 LEU B CB  1 
ATOM   4469 C CG  . LEU B 2 253 ? -15.204 7.535   -21.925 1   26.49  ? 423 LEU B CG  1 
ATOM   4470 C CD1 . LEU B 2 253 ? -13.902 7.115   -22.593 1   26     ? 423 LEU B CD1 1 
ATOM   4471 C CD2 . LEU B 2 253 ? -15.351 9.069   -22.012 1   26.09  ? 423 LEU B CD2 1 
ATOM   4472 N N   . LEU B 2 254 ? -19.285 4.899   -22.474 1   28     ? 424 LEU B N   1 
ATOM   4473 C CA  . LEU B 2 254 ? -20.449 4.337   -23.163 1   29.76  ? 424 LEU B CA  1 
ATOM   4474 C C   . LEU B 2 254 ? -21.645 5.296   -23.087 1   32.1   ? 424 LEU B C   1 
ATOM   4475 O O   . LEU B 2 254 ? -21.735 6.136   -22.186 1   34.34  ? 424 LEU B O   1 
ATOM   4476 C CB  . LEU B 2 254 ? -20.799 2.959   -22.6   1   24.37  ? 424 LEU B CB  1 
ATOM   4477 C CG  . LEU B 2 254 ? -19.767 1.862   -22.883 1   23.75  ? 424 LEU B CG  1 
ATOM   4478 C CD1 . LEU B 2 254 ? -20.105 0.567   -22.169 1   21.32  ? 424 LEU B CD1 1 
ATOM   4479 C CD2 . LEU B 2 254 ? -19.622 1.638   -24.395 1   22.82  ? 424 LEU B CD2 1 
ATOM   4480 N N   . ASN B 2 255 ? -22.559 5.169   -24.059 1   30.35  ? 425 ASN B N   1 
ATOM   4481 C CA  . ASN B 2 255 ? -23.775 5.965   -24.091 1   29.55  ? 425 ASN B CA  1 
ATOM   4482 C C   . ASN B 2 255 ? -24.901 5.234   -23.356 1   29.37  ? 425 ASN B C   1 
ATOM   4483 O O   . ASN B 2 255 ? -25.231 4.107   -23.713 1   31.88  ? 425 ASN B O   1 
ATOM   4484 C CB  . ASN B 2 255 ? -24.146 6.3     -25.529 1   28.23  ? 425 ASN B CB  1 
ATOM   4485 C CG  . ASN B 2 255 ? -23.376 7.49    -26.04  1   29.1   ? 425 ASN B CG  1 
ATOM   4486 O OD1 . ASN B 2 255 ? -23.347 7.731   -27.254 1   31.7   ? 425 ASN B OD1 1 
ATOM   4487 N ND2 . ASN B 2 255 ? -22.776 8.261   -25.141 1   28.62  ? 425 ASN B ND2 1 
ATOM   4488 N N   . PRO B 2 256 ? -25.538 5.845   -22.328 1   27.96  ? 426 PRO B N   1 
ATOM   4489 C CA  . PRO B 2 256 ? -26.723 5.232   -21.712 1   27.12  ? 426 PRO B CA  1 
ATOM   4490 C C   . PRO B 2 256 ? -27.846 5.123   -22.748 1   27.96  ? 426 PRO B C   1 
ATOM   4491 O O   . PRO B 2 256 ? -27.974 6.005   -23.601 1   25.23  ? 426 PRO B O   1 
ATOM   4492 C CB  . PRO B 2 256 ? -27.084 6.241   -20.609 1   25.67  ? 426 PRO B CB  1 
ATOM   4493 C CG  . PRO B 2 256 ? -26.525 7.567   -21.102 1   25.07  ? 426 PRO B CG  1 
ATOM   4494 C CD  . PRO B 2 256 ? -25.221 7.183   -21.792 1   25.66  ? 426 PRO B CD  1 
ATOM   4495 N N   . PRO B 2 257 ? -28.717 4.081   -22.695 1   30.61  ? 427 PRO B N   1 
ATOM   4496 C CA  . PRO B 2 257 ? -29.861 3.972   -23.624 1   28.08  ? 427 PRO B CA  1 
ATOM   4497 C C   . PRO B 2 257 ? -30.918 5.001   -23.257 1   28.46  ? 427 PRO B C   1 
ATOM   4498 O O   . PRO B 2 257 ? -31.118 5.238   -22.08  1   29.91  ? 427 PRO B O   1 
ATOM   4499 C CB  . PRO B 2 257 ? -30.403 2.566   -23.313 1   28.76  ? 427 PRO B CB  1 
ATOM   4500 C CG  . PRO B 2 257 ? -30.019 2.302   -21.856 1   28.25  ? 427 PRO B CG  1 
ATOM   4501 C CD  . PRO B 2 257 ? -28.693 3.01    -21.677 1   27.84  ? 427 PRO B CD  1 
ATOM   4502 N N   . GLU B 2 258 ? -31.646 5.549   -24.231 1   36.83  ? 428 GLU B N   1 
ATOM   4503 C CA  . GLU B 2 258 ? -32.64  6.565   -23.918 1   37.92  ? 428 GLU B CA  1 
ATOM   4504 C C   . GLU B 2 258 ? -33.907 5.954   -23.315 1   35.31  ? 428 GLU B C   1 
ATOM   4505 O O   . GLU B 2 258 ? -34.677 6.679   -22.696 1   36.95  ? 428 GLU B O   1 
ATOM   4506 C CB  . GLU B 2 258 ? -33.022 7.348   -25.166 1   43.04  ? 428 GLU B CB  1 
ATOM   4507 C CG  . GLU B 2 258 ? -31.909 8.22    -25.737 1   54.64  ? 428 GLU B CG  1 
ATOM   4508 C CD  . GLU B 2 258 ? -32.128 8.5     -27.228 1   68.72  ? 428 GLU B CD  1 
ATOM   4509 O OE1 . GLU B 2 258 ? -33.094 7.942   -27.803 1   72.03  ? 428 GLU B OE1 1 
ATOM   4510 O OE2 . GLU B 2 258 ? -31.344 9.261   -27.844 1   73.08  ? 428 GLU B OE2 1 
ATOM   4511 N N   . THR B 2 259 ? -34.129 4.643   -23.502 1   32.44  ? 429 THR B N   1 
ATOM   4512 C CA  . THR B 2 259 ? -35.307 3.945   -22.981 1   32.89  ? 429 THR B CA  1 
ATOM   4513 C C   . THR B 2 259 ? -34.975 2.497   -22.61  1   32.97  ? 429 THR B C   1 
ATOM   4514 O O   . THR B 2 259 ? -34.109 1.873   -23.222 1   33.2   ? 429 THR B O   1 
ATOM   4515 C CB  . THR B 2 259 ? -36.486 3.948   -23.967 1   32.01  ? 429 THR B CB  1 
ATOM   4516 O OG1 . THR B 2 259 ? -36.125 3.23    -25.147 1   28.35  ? 429 THR B OG1 1 
ATOM   4517 C CG2 . THR B 2 259 ? -36.987 5.339   -24.308 1   31.41  ? 429 THR B CG2 1 
ATOM   4518 N N   . LEU B 2 260 ? -35.751 1.932   -21.677 1   33.72  ? 430 LEU B N   1 
ATOM   4519 C CA  . LEU B 2 260 ? -35.565 0.553   -21.264 1   36.83  ? 430 LEU B CA  1 
ATOM   4520 C C   . LEU B 2 260 ? -36.551 -0.376  -21.968 1   43.56  ? 430 LEU B C   1 
ATOM   4521 O O   . LEU B 2 260 ? -36.356 -1.597  -21.958 1   39.72  ? 430 LEU B O   1 
ATOM   4522 C CB  . LEU B 2 260 ? -35.748 0.524   -19.752 1   34.47  ? 430 LEU B CB  1 
ATOM   4523 C CG  . LEU B 2 260 ? -34.818 1.456   -18.976 1   33.88  ? 430 LEU B CG  1 
ATOM   4524 C CD1 . LEU B 2 260 ? -34.964 1.28    -17.474 1   36.19  ? 430 LEU B CD1 1 
ATOM   4525 C CD2 . LEU B 2 260 ? -33.391 1.212   -19.387 1   30.64  ? 430 LEU B CD2 1 
ATOM   4526 N N   . ASN B 2 261 ? -37.614 0.219   -22.543 1   55.29  ? 431 ASN B N   1 
ATOM   4527 C CA  . ASN B 2 261 ? -38.668 -0.513  -23.242 1   70.05  ? 431 ASN B CA  1 
ATOM   4528 C C   . ASN B 2 261 ? -39.147 -1.702  -22.403 1   73.77  ? 431 ASN B C   1 
ATOM   4529 O O   . ASN B 2 261 ? -39.184 -2.839  -22.896 1   71.68  ? 431 ASN B O   1 
ATOM   4530 C CB  . ASN B 2 261 ? -38.227 -0.988  -24.628 1   74.17  ? 431 ASN B CB  1 
ATOM   4531 C CG  . ASN B 2 261 ? -37.452 0.062   -25.389 1   81.01  ? 431 ASN B CG  1 
ATOM   4532 O OD1 . ASN B 2 261 ? -36.243 0.225   -25.178 1   93.13  ? 431 ASN B OD1 1 
ATOM   4533 N ND2 . ASN B 2 261 ? -38.121 0.768   -26.288 1   74.44  ? 431 ASN B ND2 1 
ATOM   4534 N N   . VAL B 2 262 ? -39.478 -1.424  -21.129 1   68.38  ? 432 VAL B N   1 
ATOM   4535 C CA  . VAL B 2 262 ? -40.01  -2.422  -20.211 1   71.42  ? 432 VAL B CA  1 
ATOM   4536 C C   . VAL B 2 262 ? -39.911 -1.906  -18.755 1   64.81  ? 432 VAL B C   1 
ATOM   4537 O O   . VAL B 2 262 ? -38.828 -2.045  -18.113 1   54.57  ? 432 VAL B O   1 
ATOM   4538 C CB  . VAL B 2 262 ? -39.385 -3.822  -20.43  1   81.57  ? 432 VAL B CB  1 
ATOM   4539 C CG1 . VAL B 2 262 ? -37.848 -3.807  -20.39  1   81.13  ? 432 VAL B CG1 1 
ATOM   4540 C CG2 . VAL B 2 262 ? -40.02  -4.905  -19.546 1   79.17  ? 432 VAL B CG2 1 
ATOM   4541 N N   . SER C 1 4   ? -14.928 4.724   28.932  1   35.53  ? 0   SER C N   1 
ATOM   4542 C CA  . SER C 1 4   ? -16.401 4.62    28.774  1   38.75  ? 0   SER C CA  1 
ATOM   4543 C C   . SER C 1 4   ? -16.969 5.995   28.417  1   33.82  ? 0   SER C C   1 
ATOM   4544 O O   . SER C 1 4   ? -17.605 6.127   27.36   1   32.89  ? 0   SER C O   1 
ATOM   4545 C CB  . SER C 1 4   ? -17.019 4.088   30.03   1   40.8   ? 0   SER C CB  1 
ATOM   4546 O OG  . SER C 1 4   ? -16.832 4.978   31.121  1   41.68  ? 0   SER C OG  1 
ATOM   4547 N N   . MET C 1 5   ? -16.712 6.977   29.27   1   32.89  ? 1   MET C N   1 
ATOM   4548 C CA  . MET C 1 5   ? -17.188 8.357   29.032  1   33.93  ? 1   MET C CA  1 
ATOM   4549 C C   . MET C 1 5   ? -16.011 9.187   28.527  1   30.27  ? 1   MET C C   1 
ATOM   4550 O O   . MET C 1 5   ? -16.097 10.419  28.567  1   29.67  ? 1   MET C O   1 
ATOM   4551 C CB  . MET C 1 5   ? -17.699 8.954   30.345  1   35.05  ? 1   MET C CB  1 
ATOM   4552 C CG  . MET C 1 5   ? -18.623 8.04    31.109  1   32.91  ? 1   MET C CG  1 
ATOM   4553 S SD  . MET C 1 5   ? -20.079 7.721   30.101  1   38.03  ? 1   MET C SD  1 
ATOM   4554 C CE  . MET C 1 5   ? -20.769 9.377   30.037  1   37.6   ? 1   MET C CE  1 
ATOM   4555 N N   . GLU C 1 6   ? -14.948 8.516   28.098  1   27.63  ? 2   GLU C N   1 
ATOM   4556 C CA  . GLU C 1 6   ? -13.748 9.233   27.614  1   31.6   ? 2   GLU C CA  1 
ATOM   4557 C C   . GLU C 1 6   ? -14.145 10.108  26.428  1   28.65  ? 2   GLU C C   1 
ATOM   4558 O O   . GLU C 1 6   ? -13.533 11.164  26.239  1   28.62  ? 2   GLU C O   1 
ATOM   4559 C CB  . GLU C 1 6   ? -12.643 8.269   27.193  1   40.68  ? 2   GLU C CB  1 
ATOM   4560 C CG  . GLU C 1 6   ? -11.367 8.984   26.759  1   54.63  ? 2   GLU C CG  1 
ATOM   4561 C CD  . GLU C 1 6   ? -10.666 9.763   27.857  1   64.79  ? 2   GLU C CD  1 
ATOM   4562 O OE1 . GLU C 1 6   ? -11.021 9.565   29.039  1   69.41  ? 2   GLU C OE1 1 
ATOM   4563 O OE2 . GLU C 1 6   ? -9.767  10.568  27.535  1   60.84  ? 2   GLU C OE2 1 
ATOM   4564 N N   . ASN C 1 7   ? -15.14  9.664   25.67   1   27.26  ? 3   ASN C N   1 
ATOM   4565 C CA  . ASN C 1 7   ? -15.544 10.444  24.51   1   28.23  ? 3   ASN C CA  1 
ATOM   4566 C C   . ASN C 1 7   ? -16.479 11.588  24.878  1   25.79  ? 3   ASN C C   1 
ATOM   4567 O O   . ASN C 1 7   ? -16.777 12.412  24.02   1   25.84  ? 3   ASN C O   1 
ATOM   4568 C CB  . ASN C 1 7   ? -16.181 9.591   23.422  1   29.8   ? 3   ASN C CB  1 
ATOM   4569 C CG  . ASN C 1 7   ? -15.149 8.689   22.803  1   30.74  ? 3   ASN C CG  1 
ATOM   4570 O OD1 . ASN C 1 7   ? -13.98  9.096   22.657  1   32.17  ? 3   ASN C OD1 1 
ATOM   4571 N ND2 . ASN C 1 7   ? -15.548 7.458   22.514  1   26.99  ? 3   ASN C ND2 1 
ATOM   4572 N N   . PHE C 1 8   ? -16.897 11.661  26.147  1   22.8   ? 4   PHE C N   1 
ATOM   4573 C CA  . PHE C 1 8   ? -17.73  12.763  26.59   1   21.92  ? 4   PHE C CA  1 
ATOM   4574 C C   . PHE C 1 8   ? -16.923 13.808  27.362  1   23.57  ? 4   PHE C C   1 
ATOM   4575 O O   . PHE C 1 8   ? -16.223 13.47   28.313  1   25.48  ? 4   PHE C O   1 
ATOM   4576 C CB  . PHE C 1 8   ? -18.892 12.185  27.389  1   20     ? 4   PHE C CB  1 
ATOM   4577 C CG  . PHE C 1 8   ? -19.856 11.412  26.508  1   19.38  ? 4   PHE C CG  1 
ATOM   4578 C CD1 . PHE C 1 8   ? -20.694 12.077  25.626  1   18.54  ? 4   PHE C CD1 1 
ATOM   4579 C CD2 . PHE C 1 8   ? -19.898 10.022  26.552  1   20     ? 4   PHE C CD2 1 
ATOM   4580 C CE1 . PHE C 1 8   ? -21.554 11.367  24.809  1   19.34  ? 4   PHE C CE1 1 
ATOM   4581 C CE2 . PHE C 1 8   ? -20.776 9.315   25.752  1   19.25  ? 4   PHE C CE2 1 
ATOM   4582 C CZ  . PHE C 1 8   ? -21.603 9.99    24.881  1   20.13  ? 4   PHE C CZ  1 
ATOM   4583 N N   . GLN C 1 9   ? -17.055 15.072  26.927  1   24.21  ? 5   GLN C N   1 
ATOM   4584 C CA  . GLN C 1 9   ? -16.617 16.274  27.623  1   26.11  ? 5   GLN C CA  1 
ATOM   4585 C C   . GLN C 1 9   ? -17.819 16.938  28.302  1   27.97  ? 5   GLN C C   1 
ATOM   4586 O O   . GLN C 1 9   ? -18.745 17.428  27.636  1   25.58  ? 5   GLN C O   1 
ATOM   4587 C CB  . GLN C 1 9   ? -15.977 17.254  26.635  1   26.37  ? 5   GLN C CB  1 
ATOM   4588 C CG  . GLN C 1 9   ? -15.466 18.539  27.269  1   31.36  ? 5   GLN C CG  1 
ATOM   4589 C CD  . GLN C 1 9   ? -14.375 18.264  28.285  1   38.16  ? 5   GLN C CD  1 
ATOM   4590 O OE1 . GLN C 1 9   ? -13.268 17.829  27.936  1   39.06  ? 5   GLN C OE1 1 
ATOM   4591 N NE2 . GLN C 1 9   ? -14.697 18.468  29.558  1   35.79  ? 5   GLN C NE2 1 
ATOM   4592 N N   . LYS C 1 10  ? -17.783 16.965  29.646  1   30.25  ? 6   LYS C N   1 
ATOM   4593 C CA  . LYS C 1 10  ? -18.778 17.674  30.444  1   30.52  ? 6   LYS C CA  1 
ATOM   4594 C C   . LYS C 1 10  ? -18.687 19.17   30.141  1   26.94  ? 6   LYS C C   1 
ATOM   4595 O O   . LYS C 1 10  ? -17.596 19.7    29.919  1   24.64  ? 6   LYS C O   1 
ATOM   4596 C CB  . LYS C 1 10  ? -18.682 17.262  31.92   1   35.98  ? 6   LYS C CB  1 
ATOM   4597 C CG  . LYS C 1 10  ? -19.275 15.871  32.166  1   44.94  ? 6   LYS C CG  1 
ATOM   4598 C CD  . LYS C 1 10  ? -19.289 15.314  33.586  1   50.72  ? 6   LYS C CD  1 
ATOM   4599 C CE  . LYS C 1 10  ? -20.063 14.02   33.653  1   51.54  ? 6   LYS C CE  1 
ATOM   4600 N NZ  . LYS C 1 10  ? -19.249 12.952  33.058  1   51.64  ? 6   LYS C NZ  1 
ATOM   4601 N N   . VAL C 1 11  ? -19.852 19.821  30.061  1   23.67  ? 7   VAL C N   1 
ATOM   4602 C CA  . VAL C 1 11  ? -19.922 21.219  29.678  1   24.3   ? 7   VAL C CA  1 
ATOM   4603 C C   . VAL C 1 11  ? -20.493 22.028  30.843  1   25.82  ? 7   VAL C C   1 
ATOM   4604 O O   . VAL C 1 11  ? -19.913 23.025  31.243  1   27.67  ? 7   VAL C O   1 
ATOM   4605 C CB  . VAL C 1 11  ? -20.706 21.414  28.368  1   24.33  ? 7   VAL C CB  1 
ATOM   4606 C CG1 . VAL C 1 11  ? -20.949 22.879  28.034  1   23.79  ? 7   VAL C CG1 1 
ATOM   4607 C CG2 . VAL C 1 11  ? -20.015 20.713  27.204  1   25.28  ? 7   VAL C CG2 1 
ATOM   4608 N N   . GLU C 1 12  ? -21.61  21.58   31.414  1   27.85  ? 8   GLU C N   1 
ATOM   4609 C CA  . GLU C 1 12  ? -22.192 22.246  32.565  1   31.87  ? 8   GLU C CA  1 
ATOM   4610 C C   . GLU C 1 12  ? -23.213 21.327  33.235  1   35.23  ? 8   GLU C C   1 
ATOM   4611 O O   . GLU C 1 12  ? -23.736 20.4    32.613  1   35.81  ? 8   GLU C O   1 
ATOM   4612 C CB  . GLU C 1 12  ? -22.79  23.594  32.153  1   34.74  ? 8   GLU C CB  1 
ATOM   4613 C CG  . GLU C 1 12  ? -24.062 23.478  31.315  1   43.24  ? 8   GLU C CG  1 
ATOM   4614 C CD  . GLU C 1 12  ? -24.475 24.761  30.613  1   46.96  ? 8   GLU C CD  1 
ATOM   4615 O OE1 . GLU C 1 12  ? -23.635 25.237  29.806  1   43.01  ? 8   GLU C OE1 1 
ATOM   4616 O OE2 . GLU C 1 12  ? -25.608 25.265  30.853  1   44.41  ? 8   GLU C OE2 1 
ATOM   4617 N N   . LYS C 1 13  ? -23.495 21.611  34.513  1   42.56  ? 9   LYS C N   1 
ATOM   4618 C CA  . LYS C 1 13  ? -24.606 20.994  35.217  1   49.76  ? 9   LYS C CA  1 
ATOM   4619 C C   . LYS C 1 13  ? -25.882 21.666  34.711  1   50.19  ? 9   LYS C C   1 
ATOM   4620 O O   . LYS C 1 13  ? -25.881 22.876  34.504  1   54.58  ? 9   LYS C O   1 
ATOM   4621 C CB  . LYS C 1 13  ? -24.351 21.127  36.725  1   52.7   ? 9   LYS C CB  1 
ATOM   4622 C CG  . LYS C 1 13  ? -25.414 20.452  37.603  1   60.43  ? 9   LYS C CG  1 
ATOM   4623 C CD  . LYS C 1 13  ? -25.196 20.506  39.117  1   70.99  ? 9   LYS C CD  1 
ATOM   4624 C CE  . LYS C 1 13  ? -26.28  19.849  39.933  1   76.23  ? 9   LYS C CE  1 
ATOM   4625 N NZ  . LYS C 1 13  ? -26.03  19.925  41.373  1   67.73  ? 9   LYS C NZ  1 
ATOM   4626 N N   . ILE C 1 14  ? -26.938 20.881  34.456  1   43.67  ? 10  ILE C N   1 
ATOM   4627 C CA  . ILE C 1 14  ? -28.17  21.432  33.906  1   45.87  ? 10  ILE C CA  1 
ATOM   4628 C C   . ILE C 1 14  ? -29.358 21.086  34.803  1   52.84  ? 10  ILE C C   1 
ATOM   4629 O O   . ILE C 1 14  ? -30.461 21.589  34.593  1   59.97  ? 10  ILE C O   1 
ATOM   4630 C CB  . ILE C 1 14  ? -28.422 21.013  32.444  1   40.44  ? 10  ILE C CB  1 
ATOM   4631 C CG1 . ILE C 1 14  ? -28.551 19.493  32.271  1   40.3   ? 10  ILE C CG1 1 
ATOM   4632 C CG2 . ILE C 1 14  ? -27.348 21.595  31.532  1   43.11  ? 10  ILE C CG2 1 
ATOM   4633 C CD1 . ILE C 1 14  ? -28.649 19.041  30.823  1   38.36  ? 10  ILE C CD1 1 
ATOM   4634 N N   . GLY C 1 15  ? -29.136 20.234  35.805  1   51.24  ? 11  GLY C N   1 
ATOM   4635 C CA  . GLY C 1 15  ? -30.256 19.77   36.603  1   56.28  ? 11  GLY C CA  1 
ATOM   4636 C C   . GLY C 1 15  ? -29.835 18.659  37.553  1   66.21  ? 11  GLY C C   1 
ATOM   4637 O O   . GLY C 1 15  ? -28.667 18.249  37.562  1   66.5   ? 11  GLY C O   1 
ATOM   4638 N N   . GLU C 1 16  ? -30.788 18.207  38.363  1   74.58  ? 12  GLU C N   1 
ATOM   4639 C CA  . GLU C 1 16  ? -30.455 17.185  39.379  1   83.3   ? 12  GLU C CA  1 
ATOM   4640 C C   . GLU C 1 16  ? -31.727 16.45   39.797  1   82.72  ? 12  GLU C C   1 
ATOM   4641 O O   . GLU C 1 16  ? -32.793 16.745  39.228  1   77.39  ? 12  GLU C O   1 
ATOM   4642 C CB  . GLU C 1 16  ? -29.824 17.857  40.597  1   79.83  ? 12  GLU C CB  1 
ATOM   4643 C CG  . GLU C 1 16  ? -29.382 16.867  41.666  1   87.21  ? 12  GLU C CG  1 
ATOM   4644 C CD  . GLU C 1 16  ? -28.709 17.501  42.864  1   86.26  ? 12  GLU C CD  1 
ATOM   4645 O OE1 . GLU C 1 16  ? -28.607 18.744  42.902  1   87.22  ? 12  GLU C OE1 1 
ATOM   4646 O OE2 . GLU C 1 16  ? -28.289 16.742  43.759  1   85.8   ? 12  GLU C OE2 1 
ATOM   4647 N N   . GLY C 1 17  ? -31.603 15.538  40.76   1   95.11  ? 13  GLY C N   1 
ATOM   4648 C CA  . GLY C 1 17  ? -32.767 14.788  41.26   1   101.81 ? 13  GLY C CA  1 
ATOM   4649 C C   . GLY C 1 17  ? -32.33  13.687  42.198  1   108.05 ? 13  GLY C C   1 
ATOM   4650 O O   . GLY C 1 17  ? -31.111 13.522  42.385  1   109.1  ? 13  GLY C O   1 
ATOM   4651 N N   . THR C 1 18  ? -33.284 12.998  42.822  1   113.81 ? 14  THR C N   1 
ATOM   4652 C CA  . THR C 1 18  ? -32.931 11.845  43.666  1   111.54 ? 14  THR C CA  1 
ATOM   4653 C C   . THR C 1 18  ? -32.084 10.952  42.809  1   123.16 ? 14  THR C C   1 
ATOM   4654 O O   . THR C 1 18  ? -31.159 10.318  43.352  1   124.41 ? 14  THR C O   1 
ATOM   4655 C CB  . THR C 1 18  ? -34.209 11.148  44.116  1   100.88 ? 14  THR C CB  1 
ATOM   4656 O OG1 . THR C 1 18  ? -34.953 10.941  42.921  1   89.58  ? 14  THR C OG1 1 
ATOM   4657 C CG2 . THR C 1 18  ? -35.015 11.991  45.087  1   90.61  ? 14  THR C CG2 1 
ATOM   4658 N N   . TYR C 1 19  ? -32.38  10.918  41.506  1   121.32 ? 15  TYR C N   1 
ATOM   4659 C CA  . TYR C 1 19  ? -31.575 10.121  40.549  1   103.73 ? 15  TYR C CA  1 
ATOM   4660 C C   . TYR C 1 19  ? -30.119 10.471  40.713  1   101.37 ? 15  TYR C C   1 
ATOM   4661 O O   . TYR C 1 19  ? -29.286 9.575   40.974  1   88.13  ? 15  TYR C O   1 
ATOM   4662 C CB  . TYR C 1 19  ? -32.02  10.554  39.158  1   86.43  ? 15  TYR C CB  1 
ATOM   4663 C CG  . TYR C 1 19  ? -32.844 9.532   38.393  1   87.33  ? 15  TYR C CG  1 
ATOM   4664 C CD1 . TYR C 1 19  ? -32.608 8.17    38.526  1   73.1   ? 15  TYR C CD1 1 
ATOM   4665 C CD2 . TYR C 1 19  ? -33.858 9.936   37.536  1   87.49  ? 15  TYR C CD2 1 
ATOM   4666 C CE1 . TYR C 1 19  ? -33.354 7.241   37.823  1   66.5   ? 15  TYR C CE1 1 
ATOM   4667 C CE2 . TYR C 1 19  ? -34.615 9.016   36.835  1   71.01  ? 15  TYR C CE2 1 
ATOM   4668 C CZ  . TYR C 1 19  ? -34.359 7.666   36.977  1   60.93  ? 15  TYR C CZ  1 
ATOM   4669 O OH  . TYR C 1 19  ? -35.107 6.773   36.277  1   57.81  ? 15  TYR C OH  1 
ATOM   4670 N N   . GLY C 1 20  ? -29.809 11.756  40.555  1   92.85  ? 16  GLY C N   1 
ATOM   4671 C CA  . GLY C 1 20  ? -28.42  12.221  40.679  1   81     ? 16  GLY C CA  1 
ATOM   4672 C C   . GLY C 1 20  ? -28.292 13.567  40.011  1   72.63  ? 16  GLY C C   1 
ATOM   4673 O O   . GLY C 1 20  ? -29.217 14.375  40.157  1   66.66  ? 16  GLY C O   1 
ATOM   4674 N N   . VAL C 1 21  ? -27.212 13.772  39.261  1   66.87  ? 17  VAL C N   1 
ATOM   4675 C CA  . VAL C 1 21  ? -26.986 15.069  38.563  1   56.18  ? 17  VAL C CA  1 
ATOM   4676 C C   . VAL C 1 21  ? -27.121 14.879  37.048  1   50.5   ? 17  VAL C C   1 
ATOM   4677 O O   . VAL C 1 21  ? -26.745 13.801  36.553  1   46.18  ? 17  VAL C O   1 
ATOM   4678 C CB  . VAL C 1 21  ? -25.612 15.647  38.945  1   54.84  ? 17  VAL C CB  1 
ATOM   4679 C CG1 . VAL C 1 21  ? -24.537 14.571  39.019  1   54.3   ? 17  VAL C CG1 1 
ATOM   4680 C CG2 . VAL C 1 21  ? -25.192 16.8    38.047  1   57.94  ? 17  VAL C CG2 1 
ATOM   4681 N N   . VAL C 1 22  ? -27.696 15.862  36.365  1   41.98  ? 18  VAL C N   1 
ATOM   4682 C CA  . VAL C 1 22  ? -27.816 15.854  34.914  1   36.54  ? 18  VAL C CA  1 
ATOM   4683 C C   . VAL C 1 22  ? -26.849 16.892  34.345  1   33.7   ? 18  VAL C C   1 
ATOM   4684 O O   . VAL C 1 22  ? -26.784 18.024  34.826  1   31.64  ? 18  VAL C O   1 
ATOM   4685 C CB  . VAL C 1 22  ? -29.267 16.077  34.444  1   35.36  ? 18  VAL C CB  1 
ATOM   4686 C CG1 . VAL C 1 22  ? -29.413 16.053  32.93   1   32.97  ? 18  VAL C CG1 1 
ATOM   4687 C CG2 . VAL C 1 22  ? -30.195 15.021  35.024  1   36.98  ? 18  VAL C CG2 1 
ATOM   4688 N N   . TYR C 1 23  ? -26.083 16.482  33.326  1   31.3   ? 19  TYR C N   1 
ATOM   4689 C CA  . TYR C 1 23  ? -25.09  17.352  32.721  1   30.86  ? 19  TYR C CA  1 
ATOM   4690 C C   . TYR C 1 23  ? -25.354 17.48   31.232  1   26.78  ? 19  TYR C C   1 
ATOM   4691 O O   . TYR C 1 23  ? -25.82  16.545  30.601  1   24.01  ? 19  TYR C O   1 
ATOM   4692 C CB  . TYR C 1 23  ? -23.676 16.79   32.809  1   36.55  ? 19  TYR C CB  1 
ATOM   4693 C CG  . TYR C 1 23  ? -23.127 16.621  34.212  1   47.76  ? 19  TYR C CG  1 
ATOM   4694 C CD1 . TYR C 1 23  ? -22.504 17.688  34.861  1   55.25  ? 19  TYR C CD1 1 
ATOM   4695 C CD2 . TYR C 1 23  ? -23.201 15.392  34.869  1   54.17  ? 19  TYR C CD2 1 
ATOM   4696 C CE1 . TYR C 1 23  ? -21.966 17.53   36.131  1   60.79  ? 19  TYR C CE1 1 
ATOM   4697 C CE2 . TYR C 1 23  ? -22.669 15.225  36.139  1   60.62  ? 19  TYR C CE2 1 
ATOM   4698 C CZ  . TYR C 1 23  ? -22.05  16.299  36.766  1   59.81  ? 19  TYR C CZ  1 
ATOM   4699 O OH  . TYR C 1 23  ? -21.531 16.171  38.018  1   64.77  ? 19  TYR C OH  1 
ATOM   4700 N N   . LYS C 1 24  ? -25.083 18.669  30.697  1   25.27  ? 20  LYS C N   1 
ATOM   4701 C CA  . LYS C 1 24  ? -24.936 18.828  29.266  1   22.98  ? 20  LYS C CA  1 
ATOM   4702 C C   . LYS C 1 24  ? -23.518 18.373  28.965  1   23.45  ? 20  LYS C C   1 
ATOM   4703 O O   . LYS C 1 24  ? -22.593 18.718  29.7    1   22.66  ? 20  LYS C O   1 
ATOM   4704 C CB  . LYS C 1 24  ? -25.184 20.284  28.863  1   22.48  ? 20  LYS C CB  1 
ATOM   4705 C CG  . LYS C 1 24  ? -24.861 20.626  27.416  1   23.57  ? 20  LYS C CG  1 
ATOM   4706 C CD  . LYS C 1 24  ? -25.255 22.067  27.104  1   24.77  ? 20  LYS C CD  1 
ATOM   4707 C CE  . LYS C 1 24  ? -24.618 22.614  25.867  1   26.13  ? 20  LYS C CE  1 
ATOM   4708 N NZ  . LYS C 1 24  ? -25.079 23.988  25.671  1   26.16  ? 20  LYS C NZ  1 
ATOM   4709 N N   . ALA C 1 25  ? -23.37  17.548  27.933  1   21.63  ? 21  ALA C N   1 
ATOM   4710 C CA  . ALA C 1 25  ? -22.045 17.099  27.532  1   22.63  ? 21  ALA C CA  1 
ATOM   4711 C C   . ALA C 1 25  ? -21.917 17.12   26.007  1   22.03  ? 21  ALA C C   1 
ATOM   4712 O O   . ALA C 1 25  ? -22.908 17.31   25.292  1   21.17  ? 21  ALA C O   1 
ATOM   4713 C CB  . ALA C 1 25  ? -21.803 15.71   28.093  1   21.93  ? 21  ALA C CB  1 
ATOM   4714 N N   A ARG C 1 26  ? -20.69  16.911  25.523  0.5 20.84  ? 22  ARG C N   1 
ATOM   4715 N N   B ARG C 1 26  ? -20.687 16.927  25.521  0.5 21.35  ? 22  ARG C N   1 
ATOM   4716 C CA  A ARG C 1 26  ? -20.428 16.903  24.095  0.5 22.57  ? 22  ARG C CA  1 
ATOM   4717 C CA  B ARG C 1 26  ? -20.433 16.908  24.09   0.5 23.57  ? 22  ARG C CA  1 
ATOM   4718 C C   A ARG C 1 26  ? -19.69  15.62   23.734  0.5 23.98  ? 22  ARG C C   1 
ATOM   4719 C C   B ARG C 1 26  ? -19.692 15.622  23.733  0.5 24.59  ? 22  ARG C C   1 
ATOM   4720 O O   A ARG C 1 26  ? -18.852 15.158  24.502  0.5 26.67  ? 22  ARG C O   1 
ATOM   4721 O O   B ARG C 1 26  ? -18.858 15.159  24.506  0.5 27.32  ? 22  ARG C O   1 
ATOM   4722 C CB  A ARG C 1 26  ? -19.555 18.104  23.722  0.5 23.22  ? 22  ARG C CB  1 
ATOM   4723 C CB  B ARG C 1 26  ? -19.603 18.131  23.682  0.5 25.37  ? 22  ARG C CB  1 
ATOM   4724 C CG  A ARG C 1 26  ? -19.438 18.422  22.236  0.5 24.2   ? 22  ARG C CG  1 
ATOM   4725 C CG  B ARG C 1 26  ? -19.663 18.528  22.212  0.5 27.7   ? 22  ARG C CG  1 
ATOM   4726 C CD  A ARG C 1 26  ? -18.251 19.379  21.979  0.5 23.1   ? 22  ARG C CD  1 
ATOM   4727 C CD  B ARG C 1 26  ? -18.676 19.688  21.914  0.5 28.09  ? 22  ARG C CD  1 
ATOM   4728 N NE  A ARG C 1 26  ? -16.946 18.712  21.875  0.5 22.11  ? 22  ARG C NE  1 
ATOM   4729 N NE  B ARG C 1 26  ? -18.816 20.828  22.83   0.5 28.12  ? 22  ARG C NE  1 
ATOM   4730 C CZ  A ARG C 1 26  ? -15.85  19.043  22.562  0.5 21.1   ? 22  ARG C CZ  1 
ATOM   4731 C CZ  B ARG C 1 26  ? -19.875 21.646  22.905  0.5 28.46  ? 22  ARG C CZ  1 
ATOM   4732 N NH1 A ARG C 1 26  ? -15.893 19.92   23.546  0.5 20.3   ? 22  ARG C NH1 1 
ATOM   4733 N NH1 B ARG C 1 26  ? -20.014 22.441  23.952  0.5 27.87  ? 22  ARG C NH1 1 
ATOM   4734 N NH2 A ARG C 1 26  ? -14.702 18.462  22.28   0.5 21.32  ? 22  ARG C NH2 1 
ATOM   4735 N NH2 B ARG C 1 26  ? -20.828 21.623  21.984  0.5 26.33  ? 22  ARG C NH2 1 
ATOM   4736 N N   . ASN C 1 27  ? -20.037 15.026  22.584  1   23.34  ? 23  ASN C N   1 
ATOM   4737 C CA  . ASN C 1 27  ? -19.286 13.9    22.052  1   19.56  ? 23  ASN C CA  1 
ATOM   4738 C C   . ASN C 1 27  ? -18.074 14.499  21.354  1   18.76  ? 23  ASN C C   1 
ATOM   4739 O O   . ASN C 1 27  ? -18.234 15.292  20.431  1   18.57  ? 23  ASN C O   1 
ATOM   4740 C CB  . ASN C 1 27  ? -20.144 13.047  21.121  1   18.43  ? 23  ASN C CB  1 
ATOM   4741 C CG  . ASN C 1 27  ? -19.505 11.727  20.745  1   18.5   ? 23  ASN C CG  1 
ATOM   4742 O OD1 . ASN C 1 27  ? -18.347 11.675  20.299  1   17.37  ? 23  ASN C OD1 1 
ATOM   4743 N ND2 . ASN C 1 27  ? -20.231 10.642  20.967  1   17.54  ? 23  ASN C ND2 1 
ATOM   4744 N N   . LYS C 1 28  ? -16.882 14.167  21.849  1   20.15  ? 24  LYS C N   1 
ATOM   4745 C CA  . LYS C 1 28  ? -15.653 14.792  21.385  1   24.11  ? 24  LYS C CA  1 
ATOM   4746 C C   . LYS C 1 28  ? -15.32  14.308  19.976  1   24.34  ? 24  LYS C C   1 
ATOM   4747 O O   . LYS C 1 28  ? -14.576 14.983  19.265  1   28.84  ? 24  LYS C O   1 
ATOM   4748 C CB  . LYS C 1 28  ? -14.467 14.466  22.303  1   27.58  ? 24  LYS C CB  1 
ATOM   4749 C CG  . LYS C 1 28  ? -14.58  14.957  23.744  1   32.54  ? 24  LYS C CG  1 
ATOM   4750 C CD  . LYS C 1 28  ? -13.932 13.975  24.716  1   35.63  ? 24  LYS C CD  1 
ATOM   4751 C CE  . LYS C 1 28  ? -13.373 14.713  25.905  1   37.67  ? 24  LYS C CE  1 
ATOM   4752 N NZ  . LYS C 1 28  ? -12.182 14.057  26.456  1   32.7   ? 24  LYS C NZ  1 
ATOM   4753 N N   . LEU C 1 29  ? -15.865 13.147  19.588  1   21.64  ? 25  LEU C N   1 
ATOM   4754 C CA  . LEU C 1 29  ? -15.602 12.559  18.284  1   18.9   ? 25  LEU C CA  1 
ATOM   4755 C C   . LEU C 1 29  ? -16.628 12.996  17.238  1   20.26  ? 25  LEU C C   1 
ATOM   4756 O O   . LEU C 1 29  ? -16.262 13.134  16.075  1   22.77  ? 25  LEU C O   1 
ATOM   4757 C CB  . LEU C 1 29  ? -15.548 11.046  18.435  1   15.3   ? 25  LEU C CB  1 
ATOM   4758 C CG  . LEU C 1 29  ? -14.234 10.507  18.998  1   13.08  ? 25  LEU C CG  1 
ATOM   4759 C CD1 . LEU C 1 29  ? -14.346 9.019   19.243  1   11.91  ? 25  LEU C CD1 1 
ATOM   4760 C CD2 . LEU C 1 29  ? -13.135 10.828  18.018  1   12.22  ? 25  LEU C CD2 1 
ATOM   4761 N N   . THR C 1 30  ? -17.898 13.198  17.629  1   19.78  ? 26  THR C N   1 
ATOM   4762 C CA  . THR C 1 30  ? -18.985 13.405  16.668  1   18.99  ? 26  THR C CA  1 
ATOM   4763 C C   . THR C 1 30  ? -19.533 14.83   16.715  1   20.64  ? 26  THR C C   1 
ATOM   4764 O O   . THR C 1 30  ? -20.2   15.252  15.762  1   19.57  ? 26  THR C O   1 
ATOM   4765 C CB  . THR C 1 30  ? -20.124 12.414  16.858  1   17.53  ? 26  THR C CB  1 
ATOM   4766 O OG1 . THR C 1 30  ? -20.823 12.873  18.008  1   20.75  ? 26  THR C OG1 1 
ATOM   4767 C CG2 . THR C 1 30  ? -19.649 10.992  17.049  1   16.34  ? 26  THR C CG2 1 
ATOM   4768 N N   . GLY C 1 31  ? -19.241 15.556  17.814  1   22.16  ? 27  GLY C N   1 
ATOM   4769 C CA  . GLY C 1 31  ? -19.717 16.919  18.03   1   22.34  ? 27  GLY C CA  1 
ATOM   4770 C C   . GLY C 1 31  ? -21.084 16.949  18.735  1   25.24  ? 27  GLY C C   1 
ATOM   4771 O O   . GLY C 1 31  ? -21.549 18.021  19.143  1   26.36  ? 27  GLY C O   1 
ATOM   4772 N N   . GLU C 1 32  ? -21.731 15.776  18.877  1   21.93  ? 28  GLU C N   1 
ATOM   4773 C CA  . GLU C 1 32  ? -23.082 15.709  19.416  1   21.57  ? 28  GLU C CA  1 
ATOM   4774 C C   . GLU C 1 32  ? -23.128 16.261  20.847  1   23.14  ? 28  GLU C C   1 
ATOM   4775 O O   . GLU C 1 32  ? -22.297 15.926  21.696  1   24.81  ? 28  GLU C O   1 
ATOM   4776 C CB  . GLU C 1 32  ? -23.597 14.28   19.313  1   20.4   ? 28  GLU C CB  1 
ATOM   4777 C CG  . GLU C 1 32  ? -25.039 14.126  19.799  1   22.41  ? 28  GLU C CG  1 
ATOM   4778 C CD  . GLU C 1 32  ? -25.547 12.697  19.654  1   25.28  ? 28  GLU C CD  1 
ATOM   4779 O OE1 . GLU C 1 32  ? -24.752 11.711  19.811  1   25.85  ? 28  GLU C OE1 1 
ATOM   4780 O OE2 . GLU C 1 32  ? -26.768 12.571  19.393  1   27.47  ? 28  GLU C OE2 1 
ATOM   4781 N N   . VAL C 1 33  ? -24.099 17.146  21.103  1   21.6   ? 29  VAL C N   1 
ATOM   4782 C CA  . VAL C 1 33  ? -24.365 17.666  22.434  1   19.52  ? 29  VAL C CA  1 
ATOM   4783 C C   . VAL C 1 33  ? -25.438 16.774  23.044  1   19.83  ? 29  VAL C C   1 
ATOM   4784 O O   . VAL C 1 33  ? -26.458 16.515  22.41   1   22.18  ? 29  VAL C O   1 
ATOM   4785 C CB  . VAL C 1 33  ? -24.833 19.134  22.36   1   18.85  ? 29  VAL C CB  1 
ATOM   4786 C CG1 . VAL C 1 33  ? -25.146 19.696  23.742  1   18.32  ? 29  VAL C CG1 1 
ATOM   4787 C CG2 . VAL C 1 33  ? -23.837 20.022  21.61   1   17.3   ? 29  VAL C CG2 1 
ATOM   4788 N N   . VAL C 1 34  ? -25.195 16.276  24.26   1   18.22  ? 30  VAL C N   1 
ATOM   4789 C CA  . VAL C 1 34  ? -26.103 15.332  24.898  1   16.54  ? 30  VAL C CA  1 
ATOM   4790 C C   . VAL C 1 34  ? -26.382 15.791  26.327  1   17.26  ? 30  VAL C C   1 
ATOM   4791 O O   . VAL C 1 34  ? -25.664 16.619  26.884  1   17.5   ? 30  VAL C O   1 
ATOM   4792 C CB  . VAL C 1 34  ? -25.541 13.891  24.904  1   15.38  ? 30  VAL C CB  1 
ATOM   4793 C CG1 . VAL C 1 34  ? -25.206 13.395  23.504  1   14.36  ? 30  VAL C CG1 1 
ATOM   4794 C CG2 . VAL C 1 34  ? -24.326 13.724  25.821  1   14.64  ? 30  VAL C CG2 1 
ATOM   4795 N N   . ALA C 1 35  ? -27.419 15.206  26.934  1   17.57  ? 31  ALA C N   1 
ATOM   4796 C CA  . ALA C 1 35  ? -27.62  15.26   28.371  1   17.64  ? 31  ALA C CA  1 
ATOM   4797 C C   . ALA C 1 35  ? -27.217 13.906  28.928  1   19.53  ? 31  ALA C C   1 
ATOM   4798 O O   . ALA C 1 35  ? -27.68  12.888  28.417  1   21.31  ? 31  ALA C O   1 
ATOM   4799 C CB  . ALA C 1 35  ? -29.082 15.569  28.697  1   15.89  ? 31  ALA C CB  1 
ATOM   4800 N N   . LEU C 1 36  ? -26.357 13.916  29.955  1   22.6   ? 32  LEU C N   1 
ATOM   4801 C CA  . LEU C 1 36  ? -25.91  12.73   30.684  1   24.85  ? 32  LEU C CA  1 
ATOM   4802 C C   . LEU C 1 36  ? -26.59  12.667  32.046  1   25.73  ? 32  LEU C C   1 
ATOM   4803 O O   . LEU C 1 36  ? -26.377 13.551  32.881  1   28.29  ? 32  LEU C O   1 
ATOM   4804 C CB  . LEU C 1 36  ? -24.4   12.807  30.902  1   23.3   ? 32  LEU C CB  1 
ATOM   4805 C CG  . LEU C 1 36  ? -23.533 12.762  29.644  1   23.85  ? 32  LEU C CG  1 
ATOM   4806 C CD1 . LEU C 1 36  ? -22.059 12.747  30.044  1   23.93  ? 32  LEU C CD1 1 
ATOM   4807 C CD2 . LEU C 1 36  ? -23.887 11.548  28.799  1   26.04  ? 32  LEU C CD2 1 
ATOM   4808 N N   . LYS C 1 37  ? -27.398 11.628  32.254  1   26.26  ? 33  LYS C N   1 
ATOM   4809 C CA  . LYS C 1 37  ? -27.973 11.348  33.562  1   28.39  ? 33  LYS C CA  1 
ATOM   4810 C C   . LYS C 1 37  ? -27.091 10.287  34.217  1   28.67  ? 33  LYS C C   1 
ATOM   4811 O O   . LYS C 1 37  ? -26.946 9.196   33.681  1   33.88  ? 33  LYS C O   1 
ATOM   4812 C CB  . LYS C 1 37  ? -29.442 10.948  33.378  1   29.95  ? 33  LYS C CB  1 
ATOM   4813 C CG  . LYS C 1 37  ? -30.355 11.09   34.574  1   34.59  ? 33  LYS C CG  1 
ATOM   4814 C CD  . LYS C 1 37  ? -31.777 10.528  34.445  1   40.72  ? 33  LYS C CD  1 
ATOM   4815 C CE  . LYS C 1 37  ? -32.811 11.494  33.926  1   47.8   ? 33  LYS C CE  1 
ATOM   4816 N NZ  . LYS C 1 37  ? -34.197 11.003  34.02   1   50.02  ? 33  LYS C NZ  1 
ATOM   4817 N N   . LYS C 1 38  ? -26.464 10.637  35.344  1   28.62  ? 34  LYS C N   1 
ATOM   4818 C CA  . LYS C 1 38  ? -25.577 9.749   36.078  1   32.02  ? 34  LYS C CA  1 
ATOM   4819 C C   . LYS C 1 38  ? -26.319 9.179   37.287  1   32.79  ? 34  LYS C C   1 
ATOM   4820 O O   . LYS C 1 38  ? -26.724 9.934   38.171  1   36.49  ? 34  LYS C O   1 
ATOM   4821 C CB  . LYS C 1 38  ? -24.341 10.52   36.554  1   30.75  ? 34  LYS C CB  1 
ATOM   4822 C CG  . LYS C 1 38  ? -23.332 9.706   37.368  1   34.23  ? 34  LYS C CG  1 
ATOM   4823 C CD  . LYS C 1 38  ? -22.181 10.522  37.972  1   36.09  ? 34  LYS C CD  1 
ATOM   4824 C CE  . LYS C 1 38  ? -22.529 11.114  39.299  1   39.92  ? 34  LYS C CE  1 
ATOM   4825 N NZ  . LYS C 1 38  ? -21.343 11.493  40.076  1   43.2   ? 34  LYS C NZ  1 
ATOM   4826 N N   . ILE C 1 39  ? -26.467 7.843   37.324  1   31.18  ? 35  ILE C N   1 
ATOM   4827 C CA  . ILE C 1 39  ? -27.192 7.15    38.385  1   31.69  ? 35  ILE C CA  1 
ATOM   4828 C C   . ILE C 1 39  ? -26.213 6.306   39.197  1   32.47  ? 35  ILE C C   1 
ATOM   4829 O O   . ILE C 1 39  ? -25.537 5.452   38.623  1   35.21  ? 35  ILE C O   1 
ATOM   4830 C CB  . ILE C 1 39  ? -28.343 6.302   37.808  1   29.16  ? 35  ILE C CB  1 
ATOM   4831 C CG1 . ILE C 1 39  ? -29.449 7.187   37.249  1   30.72  ? 35  ILE C CG1 1 
ATOM   4832 C CG2 . ILE C 1 39  ? -28.896 5.371   38.877  1   29.21  ? 35  ILE C CG2 1 
ATOM   4833 C CD1 . ILE C 1 39  ? -30.286 6.541   36.168  1   26.22  ? 35  ILE C CD1 1 
ATOM   4834 N N   . ARG C 1 40  ? -26.147 6.587   40.496  1   35.05  ? 36  ARG C N   1 
ATOM   4835 C CA  . ARG C 1 40  ? -25.244 5.83    41.39   1   42.98  ? 36  ARG C CA  1 
ATOM   4836 C C   . ARG C 1 40  ? -25.862 4.462   41.666  1   43.31  ? 36  ARG C C   1 
ATOM   4837 O O   . ARG C 1 40  ? -27.08  4.388   41.915  1   42.56  ? 36  ARG C O   1 
ATOM   4838 C CB  . ARG C 1 40  ? -25.01  6.596   42.692  1   54.74  ? 36  ARG C CB  1 
ATOM   4839 C CG  . ARG C 1 40  ? -24.074 5.92    43.682  1   79.88  ? 36  ARG C CG  1 
ATOM   4840 C CD  . ARG C 1 40  ? -23.852 6.794   44.906  1   98.61  ? 36  ARG C CD  1 
ATOM   4841 N NE  . ARG C 1 40  ? -22.935 6.194   45.881  1   109.53 ? 36  ARG C NE  1 
ATOM   4842 C CZ  . ARG C 1 40  ? -22.438 6.837   46.93   1   105.92 ? 36  ARG C CZ  1 
ATOM   4843 N NH1 . ARG C 1 40  ? -22.111 6.171   48.022  1   107.39 ? 36  ARG C NH1 1 
ATOM   4844 N NH2 . ARG C 1 40  ? -22.273 8.147   46.884  1   89.85  ? 36  ARG C NH2 1 
ATOM   4845 N N   . LEU C 1 41  ? -25.043 3.425   41.601  1   36.22  ? 37  LEU C N   1 
ATOM   4846 C CA  . LEU C 1 41  ? -25.504 2.08    41.868  1   34.08  ? 37  LEU C CA  1 
ATOM   4847 C C   . LEU C 1 41  ? -25.099 1.706   43.294  1   41.68  ? 37  LEU C C   1 
ATOM   4848 O O   . LEU C 1 41  ? -23.912 1.696   43.654  1   46.27  ? 37  LEU C O   1 
ATOM   4849 C CB  . LEU C 1 41  ? -24.907 1.126   40.839  1   31.31  ? 37  LEU C CB  1 
ATOM   4850 C CG  . LEU C 1 41  ? -25.363 1.266   39.386  1   29.89  ? 37  LEU C CG  1 
ATOM   4851 C CD1 . LEU C 1 41  ? -24.94  0.026   38.624  1   25.76  ? 37  LEU C CD1 1 
ATOM   4852 C CD2 . LEU C 1 41  ? -26.854 1.481   39.299  1   32.36  ? 37  LEU C CD2 1 
ATOM   4853 N N   . ASP C 1 42  ? -26.111 1.369   44.094  1   41.65  ? 38  ASP C N   1 
ATOM   4854 C CA  . ASP C 1 42  ? -25.919 0.915   45.463  1   41.99  ? 38  ASP C CA  1 
ATOM   4855 C C   . ASP C 1 42  ? -25.43  -0.533  45.451  1   34.56  ? 38  ASP C C   1 
ATOM   4856 O O   . ASP C 1 42  ? -26.218 -1.449  45.716  1   32.71  ? 38  ASP C O   1 
ATOM   4857 C CB  . ASP C 1 42  ? -27.221 1.05    46.243  1   46.7   ? 38  ASP C CB  1 
ATOM   4858 C CG  . ASP C 1 42  ? -27.771 2.464   46.337  1   50.56  ? 38  ASP C CG  1 
ATOM   4859 O OD1 . ASP C 1 42  ? -26.925 3.376   46.478  1   51.62  ? 38  ASP C OD1 1 
ATOM   4860 O OD2 . ASP C 1 42  ? -29.028 2.633   46.295  1   52.51  ? 38  ASP C OD2 1 
ATOM   4861 N N   . THR C 1 43  ? -24.131 -0.718  45.173  1   27.71  ? 39  THR C N   1 
ATOM   4862 C CA  . THR C 1 43  ? -23.599 -2.026  44.813  1   26.19  ? 39  THR C CA  1 
ATOM   4863 C C   . THR C 1 43  ? -23.515 -2.959  46.028  1   24.56  ? 39  THR C C   1 
ATOM   4864 O O   . THR C 1 43  ? -23.322 -4.164  45.873  1   26.36  ? 39  THR C O   1 
ATOM   4865 C CB  . THR C 1 43  ? -22.27  -1.863  44.063  1   27.38  ? 39  THR C CB  1 
ATOM   4866 O OG1 . THR C 1 43  ? -21.303 -1.249  44.919  1   27.91  ? 39  THR C OG1 1 
ATOM   4867 C CG2 . THR C 1 43  ? -22.397 -1.013  42.806  1   26.31  ? 39  THR C CG2 1 
ATOM   4868 N N   . GLU C 1 44  ? -23.663 -2.412  47.242  1   21.89  ? 40  GLU C N   1 
ATOM   4869 C CA  . GLU C 1 44  ? -23.663 -3.246  48.431  1   21.28  ? 40  GLU C CA  1 
ATOM   4870 C C   . GLU C 1 44  ? -25.054 -3.357  49.059  1   21.49  ? 40  GLU C C   1 
ATOM   4871 O O   . GLU C 1 44  ? -25.246 -4.19   49.934  1   24.23  ? 40  GLU C O   1 
ATOM   4872 C CB  . GLU C 1 44  ? -22.675 -2.746  49.479  1   21.36  ? 40  GLU C CB  1 
ATOM   4873 C CG  . GLU C 1 44  ? -21.216 -2.899  49.06   1   23.05  ? 40  GLU C CG  1 
ATOM   4874 C CD  . GLU C 1 44  ? -20.772 -1.913  47.993  1   23.2   ? 40  GLU C CD  1 
ATOM   4875 O OE1 . GLU C 1 44  ? -20.272 -2.362  46.942  1   23.92  ? 40  GLU C OE1 1 
ATOM   4876 O OE2 . GLU C 1 44  ? -20.941 -0.698  48.203  1   24.49  ? 40  GLU C OE2 1 
ATOM   4877 N N   . THR C 1 45  ? -26.023 -2.542  48.633  1   20.02  ? 41  THR C N   1 
ATOM   4878 C CA  . THR C 1 45  ? -27.273 -2.429  49.374  1   20.79  ? 41  THR C CA  1 
ATOM   4879 C C   . THR C 1 45  ? -28.48  -2.746  48.494  1   20.71  ? 41  THR C C   1 
ATOM   4880 O O   . THR C 1 45  ? -28.981 -3.857  48.573  1   21.04  ? 41  THR C O   1 
ATOM   4881 C CB  . THR C 1 45  ? -27.383 -1.104  50.136  1   21.92  ? 41  THR C CB  1 
ATOM   4882 O OG1 . THR C 1 45  ? -27.188 0.023   49.278  1   23.48  ? 41  THR C OG1 1 
ATOM   4883 C CG2 . THR C 1 45  ? -26.358 -1.017  51.252  1   21.2   ? 41  THR C CG2 1 
ATOM   4884 N N   . GLU C 1 46  ? -28.937 -1.792  47.673  1   20.69  ? 42  GLU C N   1 
ATOM   4885 C CA  . GLU C 1 46  ? -30.223 -1.926  47.006  1   22.22  ? 42  GLU C CA  1 
ATOM   4886 C C   . GLU C 1 46  ? -30.086 -2.138  45.502  1   20.38  ? 42  GLU C C   1 
ATOM   4887 O O   . GLU C 1 46  ? -31.088 -2.429  44.873  1   19.64  ? 42  GLU C O   1 
ATOM   4888 C CB  . GLU C 1 46  ? -31.208 -0.791  47.296  1   26.48  ? 42  GLU C CB  1 
ATOM   4889 C CG  . GLU C 1 46  ? -31.718 -0.768  48.741  1   36.19  ? 42  GLU C CG  1 
ATOM   4890 C CD  . GLU C 1 46  ? -31.96  -2.1    49.464  1   42.31  ? 42  GLU C CD  1 
ATOM   4891 O OE1 . GLU C 1 46  ? -32.887 -2.883  49.109  1   39.62  ? 42  GLU C OE1 1 
ATOM   4892 O OE2 . GLU C 1 46  ? -31.184 -2.36   50.424  1   52.06  ? 42  GLU C OE2 1 
ATOM   4893 N N   . GLY C 1 47  ? -28.881 -1.987  44.924  1   19.21  ? 43  GLY C N   1 
ATOM   4894 C CA  . GLY C 1 47  ? -28.655 -2.303  43.517  1   16.72  ? 43  GLY C CA  1 
ATOM   4895 C C   . GLY C 1 47  ? -29.161 -1.196  42.6    1   18.12  ? 43  GLY C C   1 
ATOM   4896 O O   . GLY C 1 47  ? -29.082 -0.021  42.93   1   21.54  ? 43  GLY C O   1 
ATOM   4897 N N   . VAL C 1 48  ? -29.672 -1.566  41.427  1   17.29  ? 44  VAL C N   1 
ATOM   4898 C CA  . VAL C 1 48  ? -30.054 -0.578  40.435  1   16.72  ? 44  VAL C CA  1 
ATOM   4899 C C   . VAL C 1 48  ? -31.453 -0.119  40.811  1   17.67  ? 44  VAL C C   1 
ATOM   4900 O O   . VAL C 1 48  ? -32.332 -0.951  40.967  1   18.3   ? 44  VAL C O   1 
ATOM   4901 C CB  . VAL C 1 48  ? -30.069 -1.202  39.023  1   15.6   ? 44  VAL C CB  1 
ATOM   4902 C CG1 . VAL C 1 48  ? -30.618 -0.259  37.965  1   14.07  ? 44  VAL C CG1 1 
ATOM   4903 C CG2 . VAL C 1 48  ? -28.704 -1.722  38.61   1   14.44  ? 44  VAL C CG2 1 
ATOM   4904 N N   . PRO C 1 49  ? -31.719 1.198   40.948  1   18.78  ? 45  PRO C N   1 
ATOM   4905 C CA  . PRO C 1 49  ? -33.01  1.663   41.46   1   18.38  ? 45  PRO C CA  1 
ATOM   4906 C C   . PRO C 1 49  ? -34.114 1.339   40.467  1   21.37  ? 45  PRO C C   1 
ATOM   4907 O O   . PRO C 1 49  ? -33.9   1.36    39.251  1   24.62  ? 45  PRO C O   1 
ATOM   4908 C CB  . PRO C 1 49  ? -32.847 3.167   41.688  1   16.57  ? 45  PRO C CB  1 
ATOM   4909 C CG  . PRO C 1 49  ? -31.639 3.558   40.888  1   16.94  ? 45  PRO C CG  1 
ATOM   4910 C CD  . PRO C 1 49  ? -30.801 2.305   40.625  1   18.07  ? 45  PRO C CD  1 
ATOM   4911 N N   . SER C 1 50  ? -35.298 1.045   41.009  1   21.11  ? 46  SER C N   1 
ATOM   4912 C CA  . SER C 1 50  ? -36.421 0.637   40.19   1   21.87  ? 46  SER C CA  1 
ATOM   4913 C C   . SER C 1 50  ? -36.859 1.754   39.252  1   21.97  ? 46  SER C C   1 
ATOM   4914 O O   . SER C 1 50  ? -37.356 1.48    38.155  1   23.48  ? 46  SER C O   1 
ATOM   4915 C CB  . SER C 1 50  ? -37.543 0.149   41.048  1   23.23  ? 46  SER C CB  1 
ATOM   4916 O OG  . SER C 1 50  ? -37.784 1.064   42.103  1   25.03  ? 46  SER C OG  1 
ATOM   4917 N N   . THR C 1 51  ? -36.683 3.006   39.691  1   24     ? 47  THR C N   1 
ATOM   4918 C CA  . THR C 1 51  ? -37.019 4.168   38.873  1   24.08  ? 47  THR C CA  1 
ATOM   4919 C C   . THR C 1 51  ? -36.15  4.157   37.613  1   22.5   ? 47  THR C C   1 
ATOM   4920 O O   . THR C 1 51  ? -36.656 4.487   36.539  1   24.79  ? 47  THR C O   1 
ATOM   4921 C CB  . THR C 1 51  ? -36.94  5.471   39.672  1   24.97  ? 47  THR C CB  1 
ATOM   4922 O OG1 . THR C 1 51  ? -37.248 6.506   38.751  1   28.92  ? 47  THR C OG1 1 
ATOM   4923 C CG2 . THR C 1 51  ? -35.539 5.813   40.115  1   26.24  ? 47  THR C CG2 1 
ATOM   4924 N N   . ALA C 1 52  ? -34.894 3.686   37.732  1   18.3   ? 48  ALA C N   1 
ATOM   4925 C CA  . ALA C 1 52  ? -33.998 3.643   36.584  1   17.48  ? 48  ALA C CA  1 
ATOM   4926 C C   . ALA C 1 52  ? -34.396 2.497   35.654  1   18.53  ? 48  ALA C C   1 
ATOM   4927 O O   . ALA C 1 52  ? -34.399 2.665   34.443  1   21.67  ? 48  ALA C O   1 
ATOM   4928 C CB  . ALA C 1 52  ? -32.542 3.519   37.007  1   15.02  ? 48  ALA C CB  1 
ATOM   4929 N N   . ILE C 1 53  ? -34.711 1.328   36.224  1   17.61  ? 49  ILE C N   1 
ATOM   4930 C CA  . ILE C 1 53  ? -35.105 0.161   35.457  1   18.85  ? 49  ILE C CA  1 
ATOM   4931 C C   . ILE C 1 53  ? -36.358 0.454   34.619  1   21.14  ? 49  ILE C C   1 
ATOM   4932 O O   . ILE C 1 53  ? -36.431 0.056   33.456  1   20.02  ? 49  ILE C O   1 
ATOM   4933 C CB  . ILE C 1 53  ? -35.314 -1.021  36.413  1   18.24  ? 49  ILE C CB  1 
ATOM   4934 C CG1 . ILE C 1 53  ? -33.992 -1.469  36.985  1   18.04  ? 49  ILE C CG1 1 
ATOM   4935 C CG2 . ILE C 1 53  ? -36.031 -2.172  35.7    1   17.88  ? 49  ILE C CG2 1 
ATOM   4936 C CD1 . ILE C 1 53  ? -34.14  -2.271  38.26   1   21.16  ? 49  ILE C CD1 1 
ATOM   4937 N N   . ARG C 1 54  ? -37.333 1.143   35.233  1   21.15  ? 50  ARG C N   1 
ATOM   4938 C CA  . ARG C 1 54  ? -38.535 1.562   34.54   1   23.32  ? 50  ARG C CA  1 
ATOM   4939 C C   . ARG C 1 54  ? -38.222 2.597   33.457  1   24.81  ? 50  ARG C C   1 
ATOM   4940 O O   . ARG C 1 54  ? -38.7   2.457   32.338  1   24.21  ? 50  ARG C O   1 
ATOM   4941 C CB  . ARG C 1 54  ? -39.565 2.096   35.54   1   22.81  ? 50  ARG C CB  1 
ATOM   4942 C CG  . ARG C 1 54  ? -40.338 0.983   36.228  1   22.77  ? 50  ARG C CG  1 
ATOM   4943 C CD  . ARG C 1 54  ? -41.364 1.561   37.172  1   22.98  ? 50  ARG C CD  1 
ATOM   4944 N NE  . ARG C 1 54  ? -42.054 0.511   37.923  1   23.97  ? 50  ARG C NE  1 
ATOM   4945 C CZ  . ARG C 1 54  ? -42.905 0.763   38.905  1   25.62  ? 50  ARG C CZ  1 
ATOM   4946 N NH1 . ARG C 1 54  ? -43.137 2.004   39.3    1   23.18  ? 50  ARG C NH1 1 
ATOM   4947 N NH2 . ARG C 1 54  ? -43.529 -0.236  39.494  1   27.18  ? 50  ARG C NH2 1 
ATOM   4948 N N   . GLU C 1 55  ? -37.444 3.636   33.786  1   24.59  ? 51  GLU C N   1 
ATOM   4949 C CA  . GLU C 1 55  ? -37.174 4.679   32.818  1   25.93  ? 51  GLU C CA  1 
ATOM   4950 C C   . GLU C 1 55  ? -36.513 4.091   31.569  1   26.87  ? 51  GLU C C   1 
ATOM   4951 O O   . GLU C 1 55  ? -36.957 4.341   30.453  1   27.84  ? 51  GLU C O   1 
ATOM   4952 C CB  . GLU C 1 55  ? -36.334 5.816   33.403  1   29.16  ? 51  GLU C CB  1 
ATOM   4953 C CG  . GLU C 1 55  ? -36.244 6.996   32.436  1   33.85  ? 51  GLU C CG  1 
ATOM   4954 C CD  . GLU C 1 55  ? -35.578 8.27    32.903  1   35.08  ? 51  GLU C CD  1 
ATOM   4955 O OE1 . GLU C 1 55  ? -34.878 8.212   33.898  1   29.44  ? 51  GLU C OE1 1 
ATOM   4956 O OE2 . GLU C 1 55  ? -35.857 9.338   32.308  1   49.45  ? 51  GLU C OE2 1 
ATOM   4957 N N   . ILE C 1 56  ? -35.439 3.323   31.763  1   25.55  ? 52  ILE C N   1 
ATOM   4958 C CA  . ILE C 1 56  ? -34.612 2.813   30.685  1   22.51  ? 52  ILE C CA  1 
ATOM   4959 C C   . ILE C 1 56  ? -35.437 1.864   29.824  1   23.6   ? 52  ILE C C   1 
ATOM   4960 O O   . ILE C 1 56  ? -35.487 2.008   28.604  1   27.05  ? 52  ILE C O   1 
ATOM   4961 C CB  . ILE C 1 56  ? -33.344 2.127   31.239  1   21.36  ? 52  ILE C CB  1 
ATOM   4962 C CG1 . ILE C 1 56  ? -32.437 3.111   32.011  1   20.83  ? 52  ILE C CG1 1 
ATOM   4963 C CG2 . ILE C 1 56  ? -32.575 1.46    30.1    1   21.75  ? 52  ILE C CG2 1 
ATOM   4964 C CD1 . ILE C 1 56  ? -31.486 2.499   33.033  1   21.4   ? 52  ILE C CD1 1 
ATOM   4965 N N   . SER C 1 57  ? -36.069 0.881   30.468  1   25.13  ? 53  SER C N   1 
ATOM   4966 C CA  . SER C 1 57  ? -36.804 -0.168  29.778  1   27.38  ? 53  SER C CA  1 
ATOM   4967 C C   . SER C 1 57  ? -37.958 0.422   28.958  1   30.33  ? 53  SER C C   1 
ATOM   4968 O O   . SER C 1 57  ? -38.156 0.036   27.814  1   29.73  ? 53  SER C O   1 
ATOM   4969 C CB  . SER C 1 57  ? -37.282 -1.233  30.74   1   25.84  ? 53  SER C CB  1 
ATOM   4970 O OG  . SER C 1 57  ? -38.102 -0.652  31.746  1   29.69  ? 53  SER C OG  1 
ATOM   4971 N N   . LEU C 1 58  ? -38.679 1.402   29.52   1   29.03  ? 54  LEU C N   1 
ATOM   4972 C CA  . LEU C 1 58  ? -39.845 1.96    28.855  1   28.79  ? 54  LEU C CA  1 
ATOM   4973 C C   . LEU C 1 58  ? -39.426 2.869   27.705  1   30.53  ? 54  LEU C C   1 
ATOM   4974 O O   . LEU C 1 58  ? -40.077 2.861   26.646  1   34.84  ? 54  LEU C O   1 
ATOM   4975 C CB  . LEU C 1 58  ? -40.75  2.662   29.864  1   26.45  ? 54  LEU C CB  1 
ATOM   4976 C CG  . LEU C 1 58  ? -41.291 1.735   30.961  1   29.2   ? 54  LEU C CG  1 
ATOM   4977 C CD1 . LEU C 1 58  ? -42.15  2.455   31.983  1   27.87  ? 54  LEU C CD1 1 
ATOM   4978 C CD2 . LEU C 1 58  ? -42.015 0.529   30.377  1   27.28  ? 54  LEU C CD2 1 
ATOM   4979 N N   . LEU C 1 59  ? -38.356 3.644   27.927  1   25.97  ? 55  LEU C N   1 
ATOM   4980 C CA  . LEU C 1 59  ? -37.83  4.541   26.911  1   28.57  ? 55  LEU C CA  1 
ATOM   4981 C C   . LEU C 1 59  ? -37.195 3.739   25.771  1   32.07  ? 55  LEU C C   1 
ATOM   4982 O O   . LEU C 1 59  ? -37.086 4.232   24.656  1   36.37  ? 55  LEU C O   1 
ATOM   4983 C CB  . LEU C 1 59  ? -36.795 5.494   27.509  1   26.94  ? 55  LEU C CB  1 
ATOM   4984 C CG  . LEU C 1 59  ? -37.296 6.762   28.202  1   27.74  ? 55  LEU C CG  1 
ATOM   4985 C CD1 . LEU C 1 59  ? -36.096 7.531   28.716  1   29.2   ? 55  LEU C CD1 1 
ATOM   4986 C CD2 . LEU C 1 59  ? -38.131 7.641   27.305  1   25.51  ? 55  LEU C CD2 1 
ATOM   4987 N N   . LYS C 1 60  ? -36.681 2.542   26.052  1   34.18  ? 56  LYS C N   1 
ATOM   4988 C CA  . LYS C 1 60  ? -36.062 1.776   24.987  1   39.72  ? 56  LYS C CA  1 
ATOM   4989 C C   . LYS C 1 60  ? -37.103 1.401   23.928  1   43.37  ? 56  LYS C C   1 
ATOM   4990 O O   . LYS C 1 60  ? -36.76  1.274   22.755  1   42.84  ? 56  LYS C O   1 
ATOM   4991 C CB  . LYS C 1 60  ? -35.291 0.569   25.524  1   43.32  ? 56  LYS C CB  1 
ATOM   4992 C CG  . LYS C 1 60  ? -33.935 0.936   26.075  1   46.87  ? 56  LYS C CG  1 
ATOM   4993 C CD  . LYS C 1 60  ? -33.026 -0.28   26.169  1   54.76  ? 56  LYS C CD  1 
ATOM   4994 C CE  . LYS C 1 60  ? -32.401 -0.607  24.847  1   55.15  ? 56  LYS C CE  1 
ATOM   4995 N NZ  . LYS C 1 60  ? -32.231 -2.059  24.737  1   52.26  ? 56  LYS C NZ  1 
ATOM   4996 N N   . GLU C 1 61  ? -38.371 1.26    24.333  1   41.63  ? 57  GLU C N   1 
ATOM   4997 C CA  . GLU C 1 61  ? -39.392 0.872   23.379  1   43.49  ? 57  GLU C CA  1 
ATOM   4998 C C   . GLU C 1 61  ? -40.353 2.026   23.06   1   41.93  ? 57  GLU C C   1 
ATOM   4999 O O   . GLU C 1 61  ? -41.44  1.805   22.549  1   48.02  ? 57  GLU C O   1 
ATOM   5000 C CB  . GLU C 1 61  ? -40.018 -0.442  23.856  1   50.31  ? 57  GLU C CB  1 
ATOM   5001 C CG  . GLU C 1 61  ? -40.951 -0.31   25.059  1   49.41  ? 57  GLU C CG  1 
ATOM   5002 C CD  . GLU C 1 61  ? -41.764 -1.581  25.276  1   48.68  ? 57  GLU C CD  1 
ATOM   5003 O OE1 . GLU C 1 61  ? -41.187 -2.675  25.45   1   45.71  ? 57  GLU C OE1 1 
ATOM   5004 O OE2 . GLU C 1 61  ? -43.005 -1.481  25.218  1   57.38  ? 57  GLU C OE2 1 
ATOM   5005 N N   . LEU C 1 62  ? -39.956 3.266   23.332  1   37.4   ? 58  LEU C N   1 
ATOM   5006 C CA  . LEU C 1 62  ? -40.73  4.422   22.913  1   34.1   ? 58  LEU C CA  1 
ATOM   5007 C C   . LEU C 1 62  ? -39.902 5.269   21.95   1   35.93  ? 58  LEU C C   1 
ATOM   5008 O O   . LEU C 1 62  ? -39.201 6.187   22.378  1   40.19  ? 58  LEU C O   1 
ATOM   5009 C CB  . LEU C 1 62  ? -41.194 5.238   24.123  1   33.28  ? 58  LEU C CB  1 
ATOM   5010 C CG  . LEU C 1 62  ? -42.223 4.569   25.041  1   35.23  ? 58  LEU C CG  1 
ATOM   5011 C CD1 . LEU C 1 62  ? -42.456 5.347   26.316  1   33.06  ? 58  LEU C CD1 1 
ATOM   5012 C CD2 . LEU C 1 62  ? -43.532 4.311   24.33   1   32.31  ? 58  LEU C CD2 1 
ATOM   5013 N N   . ASN C 1 63  ? -40.006 4.965   20.648  1   35.2   ? 59  ASN C N   1 
ATOM   5014 C CA  . ASN C 1 63  ? -39.36  5.773   19.629  1   39.33  ? 59  ASN C CA  1 
ATOM   5015 C C   . ASN C 1 63  ? -40.389 6.647   18.919  1   34.47  ? 59  ASN C C   1 
ATOM   5016 O O   . ASN C 1 63  ? -41.179 6.167   18.117  1   36.43  ? 59  ASN C O   1 
ATOM   5017 C CB  . ASN C 1 63  ? -38.387 4.952   18.784  1   55.43  ? 59  ASN C CB  1 
ATOM   5018 C CG  . ASN C 1 63  ? -37.209 4.449   19.603  1   72.6   ? 59  ASN C CG  1 
ATOM   5019 O OD1 . ASN C 1 63  ? -37.182 3.282   20.028  1   74.08  ? 59  ASN C OD1 1 
ATOM   5020 N ND2 . ASN C 1 63  ? -36.244 5.32    19.88   1   77.85  ? 59  ASN C ND2 1 
ATOM   5021 N N   . HIS C 1 64  ? -40.394 7.938   19.263  1   33.32  ? 60  HIS C N   1 
ATOM   5022 C CA  . HIS C 1 64  ? -41.348 8.904   18.735  1   32.44  ? 60  HIS C CA  1 
ATOM   5023 C C   . HIS C 1 64  ? -40.713 10.3    18.673  1   33.05  ? 60  HIS C C   1 
ATOM   5024 O O   . HIS C 1 64  ? -39.875 10.675  19.497  1   34.76  ? 60  HIS C O   1 
ATOM   5025 C CB  . HIS C 1 64  ? -42.639 8.883   19.561  1   29.3   ? 60  HIS C CB  1 
ATOM   5026 C CG  . HIS C 1 64  ? -43.725 9.659   18.904  1   29.57  ? 60  HIS C CG  1 
ATOM   5027 N ND1 . HIS C 1 64  ? -43.827 11.016  19.115  1   30.47  ? 60  HIS C ND1 1 
ATOM   5028 C CD2 . HIS C 1 64  ? -44.72  9.337   18.054  1   26.93  ? 60  HIS C CD2 1 
ATOM   5029 C CE1 . HIS C 1 64  ? -44.852 11.494  18.411  1   28.6   ? 60  HIS C CE1 1 
ATOM   5030 N NE2 . HIS C 1 64  ? -45.416 10.494  17.774  1   26.58  ? 60  HIS C NE2 1 
ATOM   5031 N N   . PRO C 1 65  ? -41.049 11.129  17.669  1   31.97  ? 61  PRO C N   1 
ATOM   5032 C CA  . PRO C 1 65  ? -40.486 12.478  17.605  1   30.84  ? 61  PRO C CA  1 
ATOM   5033 C C   . PRO C 1 65  ? -40.8   13.343  18.818  1   31.73  ? 61  PRO C C   1 
ATOM   5034 O O   . PRO C 1 65  ? -40.057 14.292  19.042  1   32.3   ? 61  PRO C O   1 
ATOM   5035 C CB  . PRO C 1 65  ? -41.056 13.098  16.324  1   30.51  ? 61  PRO C CB  1 
ATOM   5036 C CG  . PRO C 1 65  ? -41.558 11.91   15.537  1   30.57  ? 61  PRO C CG  1 
ATOM   5037 C CD  . PRO C 1 65  ? -41.922 10.805  16.53   1   30.49  ? 61  PRO C CD  1 
ATOM   5038 N N   . ASN C 1 66  ? -41.889 13.034  19.563  1   27.79  ? 62  ASN C N   1 
ATOM   5039 C CA  . ASN C 1 66  ? -42.314 13.867  20.682  1   26.28  ? 62  ASN C CA  1 
ATOM   5040 C C   . ASN C 1 66  ? -42.036 13.207  22.041  1   28.9   ? 62  ASN C C   1 
ATOM   5041 O O   . ASN C 1 66  ? -42.626 13.604  23.05   1   30.95  ? 62  ASN C O   1 
ATOM   5042 C CB  . ASN C 1 66  ? -43.76  14.309  20.526  1   22.76  ? 62  ASN C CB  1 
ATOM   5043 C CG  . ASN C 1 66  ? -43.962 15.135  19.283  1   22.98  ? 62  ASN C CG  1 
ATOM   5044 O OD1 . ASN C 1 66  ? -44.6   14.67   18.34   1   26.95  ? 62  ASN C OD1 1 
ATOM   5045 N ND2 . ASN C 1 66  ? -43.445 16.35   19.242  1   20.61  ? 62  ASN C ND2 1 
ATOM   5046 N N   . ILE C 1 67  ? -41.14  12.208  22.067  1   25.81  ? 63  ILE C N   1 
ATOM   5047 C CA  . ILE C 1 67  ? -40.659 11.581  23.29   1   24.17  ? 63  ILE C CA  1 
ATOM   5048 C C   . ILE C 1 67  ? -39.136 11.642  23.245  1   25.98  ? 63  ILE C C   1 
ATOM   5049 O O   . ILE C 1 67  ? -38.536 11.289  22.223  1   26.91  ? 63  ILE C O   1 
ATOM   5050 C CB  . ILE C 1 67  ? -41.149 10.127  23.43   1   22.54  ? 63  ILE C CB  1 
ATOM   5051 C CG1 . ILE C 1 67  ? -42.674 10.021  23.378  1   23.47  ? 63  ILE C CG1 1 
ATOM   5052 C CG2 . ILE C 1 67  ? -40.612 9.485   24.709  1   20.87  ? 63  ILE C CG2 1 
ATOM   5053 C CD1 . ILE C 1 67  ? -43.159 8.581   23.364  1   23.88  ? 63  ILE C CD1 1 
ATOM   5054 N N   . VAL C 1 68  ? -38.536 12.094  24.358  1   24.49  ? 64  VAL C N   1 
ATOM   5055 C CA  . VAL C 1 68  ? -37.109 12.355  24.418  1   23.15  ? 64  VAL C CA  1 
ATOM   5056 C C   . VAL C 1 68  ? -36.375 11.048  24.115  1   23.15  ? 64  VAL C C   1 
ATOM   5057 O O   . VAL C 1 68  ? -36.74  9.984   24.601  1   20.59  ? 64  VAL C O   1 
ATOM   5058 C CB  . VAL C 1 68  ? -36.696 12.966  25.772  1   21.09  ? 64  VAL C CB  1 
ATOM   5059 C CG1 . VAL C 1 68  ? -36.896 11.995  26.927  1   18.62  ? 64  VAL C CG1 1 
ATOM   5060 C CG2 . VAL C 1 68  ? -35.27  13.496  25.752  1   21.41  ? 64  VAL C CG2 1 
ATOM   5061 N N   . LYS C 1 69  ? -35.349 11.135  23.274  1   23.72  ? 65  LYS C N   1 
ATOM   5062 C CA  . LYS C 1 69  ? -34.667 9.931   22.837  1   27.91  ? 65  LYS C CA  1 
ATOM   5063 C C   . LYS C 1 69  ? -33.544 9.599   23.817  1   25.52  ? 65  LYS C C   1 
ATOM   5064 O O   . LYS C 1 69  ? -32.652 10.412  24.052  1   24.75  ? 65  LYS C O   1 
ATOM   5065 C CB  . LYS C 1 69  ? -34.186 10.147  21.399  1   32.8   ? 65  LYS C CB  1 
ATOM   5066 C CG  . LYS C 1 69  ? -33.849 8.9     20.588  1   49.15  ? 65  LYS C CG  1 
ATOM   5067 C CD  . LYS C 1 69  ? -34.211 9.122   19.115  1   68.6   ? 65  LYS C CD  1 
ATOM   5068 C CE  . LYS C 1 69  ? -33.941 10.504  18.536  1   66.37  ? 65  LYS C CE  1 
ATOM   5069 N NZ  . LYS C 1 69  ? -34.909 10.902  17.506  1   61.77  ? 65  LYS C NZ  1 
ATOM   5070 N N   . LEU C 1 70  ? -33.631 8.409   24.414  1   23.17  ? 66  LEU C N   1 
ATOM   5071 C CA  . LEU C 1 70  ? -32.496 7.823   25.112  1   23.74  ? 66  LEU C CA  1 
ATOM   5072 C C   . LEU C 1 70  ? -31.557 7.25    24.048  1   25.34  ? 66  LEU C C   1 
ATOM   5073 O O   . LEU C 1 70  ? -31.962 6.38    23.287  1   26.89  ? 66  LEU C O   1 
ATOM   5074 C CB  . LEU C 1 70  ? -33.004 6.723   26.047  1   21.41  ? 66  LEU C CB  1 
ATOM   5075 C CG  . LEU C 1 70  ? -31.95  5.932   26.822  1   20.32  ? 66  LEU C CG  1 
ATOM   5076 C CD1 . LEU C 1 70  ? -31.175 6.829   27.766  1   18.12  ? 66  LEU C CD1 1 
ATOM   5077 C CD2 . LEU C 1 70  ? -32.597 4.775   27.567  1   18.57  ? 66  LEU C CD2 1 
ATOM   5078 N N   . LEU C 1 71  ? -30.325 7.765   23.974  1   22.99  ? 67  LEU C N   1 
ATOM   5079 C CA  . LEU C 1 71  ? -29.381 7.414   22.922  1   21.98  ? 67  LEU C CA  1 
ATOM   5080 C C   . LEU C 1 71  ? -28.593 6.16    23.293  1   22.43  ? 67  LEU C C   1 
ATOM   5081 O O   . LEU C 1 71  ? -28.299 5.347   22.418  1   24.75  ? 67  LEU C O   1 
ATOM   5082 C CB  . LEU C 1 71  ? -28.42  8.579   22.671  1   19.94  ? 67  LEU C CB  1 
ATOM   5083 C CG  . LEU C 1 71  ? -29.067 9.894   22.235  1   19.61  ? 67  LEU C CG  1 
ATOM   5084 C CD1 . LEU C 1 71  ? -28.029 11.005  22.15   1   18.71  ? 67  LEU C CD1 1 
ATOM   5085 C CD2 . LEU C 1 71  ? -29.78  9.745   20.901  1   18.64  ? 67  LEU C CD2 1 
ATOM   5086 N N   . ASP C 1 72  ? -28.205 6.039   24.573  1   21.77  ? 68  ASP C N   1 
ATOM   5087 C CA  . ASP C 1 72  ? -27.299 4.992   25.022  1   19.87  ? 68  ASP C CA  1 
ATOM   5088 C C   . ASP C 1 72  ? -27.421 4.82    26.531  1   19.73  ? 68  ASP C C   1 
ATOM   5089 O O   . ASP C 1 72  ? -27.881 5.73    27.237  1   19.3   ? 68  ASP C O   1 
ATOM   5090 C CB  . ASP C 1 72  ? -25.854 5.341   24.7    1   19.01  ? 68  ASP C CB  1 
ATOM   5091 C CG  . ASP C 1 72  ? -24.916 4.159   24.518  1   21.07  ? 68  ASP C CG  1 
ATOM   5092 O OD1 . ASP C 1 72  ? -25.342 3.009   24.772  1   22.57  ? 68  ASP C OD1 1 
ATOM   5093 O OD2 . ASP C 1 72  ? -23.764 4.395   24.091  1   23     ? 68  ASP C OD2 1 
ATOM   5094 N N   . VAL C 1 73  ? -26.947 3.66    27      1   19.05  ? 69  VAL C N   1 
ATOM   5095 C CA  . VAL C 1 73  ? -26.805 3.393   28.419  1   21.34  ? 69  VAL C CA  1 
ATOM   5096 C C   . VAL C 1 73  ? -25.407 2.846   28.704  1   23.4   ? 69  VAL C C   1 
ATOM   5097 O O   . VAL C 1 73  ? -25.122 1.689   28.404  1   24.28  ? 69  VAL C O   1 
ATOM   5098 C CB  . VAL C 1 73  ? -27.891 2.435   28.943  1   18.71  ? 69  VAL C CB  1 
ATOM   5099 C CG1 . VAL C 1 73  ? -27.638 2.084   30.407  1   17.9   ? 69  VAL C CG1 1 
ATOM   5100 C CG2 . VAL C 1 73  ? -29.283 3.025   28.741  1   18.15  ? 69  VAL C CG2 1 
ATOM   5101 N N   . ILE C 1 74  ? -24.554 3.672   29.321  1   25.4   ? 70  ILE C N   1 
ATOM   5102 C CA  . ILE C 1 74  ? -23.178 3.285   29.562  1   27.88  ? 70  ILE C CA  1 
ATOM   5103 C C   . ILE C 1 74  ? -23.037 2.759   30.981  1   29.37  ? 70  ILE C C   1 
ATOM   5104 O O   . ILE C 1 74  ? -23.273 3.494   31.93   1   31.07  ? 70  ILE C O   1 
ATOM   5105 C CB  . ILE C 1 74  ? -22.224 4.455   29.281  1   29.82  ? 70  ILE C CB  1 
ATOM   5106 C CG1 . ILE C 1 74  ? -22.066 4.633   27.785  1   28.66  ? 70  ILE C CG1 1 
ATOM   5107 C CG2 . ILE C 1 74  ? -20.864 4.21    29.939  1   28.22  ? 70  ILE C CG2 1 
ATOM   5108 C CD1 . ILE C 1 74  ? -21.984 6.081   27.366  1   31.8   ? 70  ILE C CD1 1 
ATOM   5109 N N   . HIS C 1 75  ? -22.606 1.497   31.083  1   34.21  ? 71  HIS C N   1 
ATOM   5110 C CA  . HIS C 1 75  ? -22.478 0.79    32.353  1   35.33  ? 71  HIS C CA  1 
ATOM   5111 C C   . HIS C 1 75  ? -21.043 0.83    32.871  1   33.16  ? 71  HIS C C   1 
ATOM   5112 O O   . HIS C 1 75  ? -20.077 0.78    32.122  1   30.21  ? 71  HIS C O   1 
ATOM   5113 C CB  . HIS C 1 75  ? -22.842 -0.697  32.251  1   34.61  ? 71  HIS C CB  1 
ATOM   5114 C CG  . HIS C 1 75  ? -24.197 -1.027  31.734  1   37.45  ? 71  HIS C CG  1 
ATOM   5115 N ND1 . HIS C 1 75  ? -25.068 -1.808  32.46   1   39.34  ? 71  HIS C ND1 1 
ATOM   5116 C CD2 . HIS C 1 75  ? -24.836 -0.707  30.593  1   40.38  ? 71  HIS C CD2 1 
ATOM   5117 C CE1 . HIS C 1 75  ? -26.191 -1.973  31.767  1   40.4   ? 71  HIS C CE1 1 
ATOM   5118 N NE2 . HIS C 1 75  ? -26.074 -1.314  30.633  1   41.71  ? 71  HIS C NE2 1 
ATOM   5119 N N   . THR C 1 76  ? -20.924 0.917   34.191  1   35.72  ? 72  THR C N   1 
ATOM   5120 C CA  . THR C 1 76  ? -19.68  0.607   34.881  1   34.53  ? 72  THR C CA  1 
ATOM   5121 C C   . THR C 1 76  ? -20.06  -0.375  35.985  1   33.6   ? 72  THR C C   1 
ATOM   5122 O O   . THR C 1 76  ? -21.216 -0.815  36.064  1   30.25  ? 72  THR C O   1 
ATOM   5123 C CB  . THR C 1 76  ? -19.011 1.88    35.413  1   31.99  ? 72  THR C CB  1 
ATOM   5124 O OG1 . THR C 1 76  ? -19.617 2.267   36.643  1   35.55  ? 72  THR C OG1 1 
ATOM   5125 C CG2 . THR C 1 76  ? -19.144 3.062   34.473  1   32.42  ? 72  THR C CG2 1 
ATOM   5126 N N   . GLU C 1 77  ? -19.092 -0.684  36.848  1   36.78  ? 73  GLU C N   1 
ATOM   5127 C CA  . GLU C 1 77  ? -19.37  -1.51   38.01   1   37.73  ? 73  GLU C CA  1 
ATOM   5128 C C   . GLU C 1 77  ? -20.127 -0.688  39.066  1   35.27  ? 73  GLU C C   1 
ATOM   5129 O O   . GLU C 1 77  ? -20.823 -1.255  39.903  1   39.68  ? 73  GLU C O   1 
ATOM   5130 C CB  . GLU C 1 77  ? -18.071 -2.166  38.492  1   41.17  ? 73  GLU C CB  1 
ATOM   5131 C CG  . GLU C 1 77  ? -18.315 -3.262  39.528  1   55.42  ? 73  GLU C CG  1 
ATOM   5132 C CD  . GLU C 1 77  ? -17.48  -3.215  40.812  1   65.92  ? 73  GLU C CD  1 
ATOM   5133 O OE1 . GLU C 1 77  ? -18.043 -2.902  41.9    1   69.35  ? 73  GLU C OE1 1 
ATOM   5134 O OE2 . GLU C 1 77  ? -16.26  -3.514  40.736  1   58.09  ? 73  GLU C OE2 1 
ATOM   5135 N N   . ASN C 1 78  ? -20.015 0.651   39.022  1   30.31  ? 74  ASN C N   1 
ATOM   5136 C CA  . ASN C 1 78  ? -20.447 1.504   40.119  1   29.28  ? 74  ASN C CA  1 
ATOM   5137 C C   . ASN C 1 78  ? -21.442 2.576   39.678  1   29.2   ? 74  ASN C C   1 
ATOM   5138 O O   . ASN C 1 78  ? -22.073 3.211   40.517  1   26.27  ? 74  ASN C O   1 
ATOM   5139 C CB  . ASN C 1 78  ? -19.245 2.103   40.833  1   30.61  ? 74  ASN C CB  1 
ATOM   5140 C CG  . ASN C 1 78  ? -18.35  1.018   41.388  1   38.52  ? 74  ASN C CG  1 
ATOM   5141 O OD1 . ASN C 1 78  ? -18.757 0.218   42.247  1   39.02  ? 74  ASN C OD1 1 
ATOM   5142 N ND2 . ASN C 1 78  ? -17.125 0.956   40.884  1   42.95  ? 74  ASN C ND2 1 
ATOM   5143 N N   . LYS C 1 79  ? -21.581 2.795   38.365  1   32.96  ? 75  LYS C N   1 
ATOM   5144 C CA  . LYS C 1 79  ? -22.393 3.904   37.887  1   32.29  ? 75  LYS C CA  1 
ATOM   5145 C C   . LYS C 1 79  ? -23.138 3.496   36.631  1   28.5   ? 75  LYS C C   1 
ATOM   5146 O O   . LYS C 1 79  ? -22.647 2.691   35.842  1   30.09  ? 75  LYS C O   1 
ATOM   5147 C CB  . LYS C 1 79  ? -21.519 5.095   37.487  1   38.24  ? 75  LYS C CB  1 
ATOM   5148 C CG  . LYS C 1 79  ? -20.745 5.814   38.581  1   55.26  ? 75  LYS C CG  1 
ATOM   5149 C CD  . LYS C 1 79  ? -21.601 6.738   39.442  1   70.12  ? 75  LYS C CD  1 
ATOM   5150 C CE  . LYS C 1 79  ? -20.819 7.857   40.084  1   73.05  ? 75  LYS C CE  1 
ATOM   5151 N NZ  . LYS C 1 79  ? -21.387 8.246   41.383  1   75.71  ? 75  LYS C NZ  1 
ATOM   5152 N N   . LEU C 1 80  ? -24.296 4.123   36.44   1   27.61  ? 76  LEU C N   1 
ATOM   5153 C CA  . LEU C 1 80  ? -24.984 4.07    35.164  1   27.45  ? 76  LEU C CA  1 
ATOM   5154 C C   . LEU C 1 80  ? -25.052 5.479   34.581  1   27.19  ? 76  LEU C C   1 
ATOM   5155 O O   . LEU C 1 80  ? -25.432 6.419   35.287  1   26.96  ? 76  LEU C O   1 
ATOM   5156 C CB  . LEU C 1 80  ? -26.378 3.515   35.433  1   27.21  ? 76  LEU C CB  1 
ATOM   5157 C CG  . LEU C 1 80  ? -26.849 2.385   34.519  1   31.11  ? 76  LEU C CG  1 
ATOM   5158 C CD1 . LEU C 1 80  ? -25.758 1.296   34.34   1   33.72  ? 76  LEU C CD1 1 
ATOM   5159 C CD2 . LEU C 1 80  ? -28.105 1.808   35.177  1   30.28  ? 76  LEU C CD2 1 
ATOM   5160 N N   . TYR C 1 81  ? -24.627 5.615   33.318  1   23.96  ? 77  TYR C N   1 
ATOM   5161 C CA  . TYR C 1 81  ? -24.796 6.866   32.6    1   25.86  ? 77  TYR C CA  1 
ATOM   5162 C C   . TYR C 1 81  ? -25.872 6.671   31.538  1   27.16  ? 77  TYR C C   1 
ATOM   5163 O O   . TYR C 1 81  ? -25.748 5.781   30.694  1   28.04  ? 77  TYR C O   1 
ATOM   5164 C CB  . TYR C 1 81  ? -23.489 7.319   31.949  1   27.03  ? 77  TYR C CB  1 
ATOM   5165 C CG  . TYR C 1 81  ? -22.42  7.75    32.93   1   26.76  ? 77  TYR C CG  1 
ATOM   5166 C CD1 . TYR C 1 81  ? -22.393 9.039   33.436  1   30.41  ? 77  TYR C CD1 1 
ATOM   5167 C CD2 . TYR C 1 81  ? -21.463 6.851   33.358  1   27.69  ? 77  TYR C CD2 1 
ATOM   5168 C CE1 . TYR C 1 81  ? -21.404 9.437   34.32   1   35.17  ? 77  TYR C CE1 1 
ATOM   5169 C CE2 . TYR C 1 81  ? -20.469 7.234   34.239  1   33.9   ? 77  TYR C CE2 1 
ATOM   5170 C CZ  . TYR C 1 81  ? -20.441 8.526   34.733  1   37.25  ? 77  TYR C CZ  1 
ATOM   5171 O OH  . TYR C 1 81  ? -19.436 8.849   35.615  1   42.2   ? 77  TYR C OH  1 
ATOM   5172 N N   . LEU C 1 82  ? -26.945 7.466   31.634  1   25.89  ? 78  LEU C N   1 
ATOM   5173 C CA  . LEU C 1 82  ? -27.951 7.54    30.583  1   25.05  ? 78  LEU C CA  1 
ATOM   5174 C C   . LEU C 1 82  ? -27.596 8.707   29.659  1   22.72  ? 78  LEU C C   1 
ATOM   5175 O O   . LEU C 1 82  ? -27.391 9.831   30.121  1   23.01  ? 78  LEU C O   1 
ATOM   5176 C CB  . LEU C 1 82  ? -29.383 7.675   31.124  1   28.05  ? 78  LEU C CB  1 
ATOM   5177 C CG  . LEU C 1 82  ? -29.842 6.823   32.321  1   27.37  ? 78  LEU C CG  1 
ATOM   5178 C CD1 . LEU C 1 82  ? -31.316 6.489   32.208  1   24.4   ? 78  LEU C CD1 1 
ATOM   5179 C CD2 . LEU C 1 82  ? -29.026 5.587   32.62   1   31.22  ? 78  LEU C CD2 1 
ATOM   5180 N N   . VAL C 1 83  ? -27.492 8.421   28.354  1   19.63  ? 79  VAL C N   1 
ATOM   5181 C CA  . VAL C 1 83  ? -27.167 9.436   27.365  1   17.89  ? 79  VAL C CA  1 
ATOM   5182 C C   . VAL C 1 83  ? -28.443 9.775   26.604  1   18.17  ? 79  VAL C C   1 
ATOM   5183 O O   . VAL C 1 83  ? -29.033 8.909   25.959  1   17.54  ? 79  VAL C O   1 
ATOM   5184 C CB  . VAL C 1 83  ? -26.086 8.914   26.409  1   16.79  ? 79  VAL C CB  1 
ATOM   5185 C CG1 . VAL C 1 83  ? -25.609 10.006  25.467  1   16.11  ? 79  VAL C CG1 1 
ATOM   5186 C CG2 . VAL C 1 83  ? -24.92  8.327   27.189  1   17.02  ? 79  VAL C CG2 1 
ATOM   5187 N N   . PHE C 1 84  ? -28.894 11.024  26.751  1   18.33  ? 80  PHE C N   1 
ATOM   5188 C CA  . PHE C 1 84  ? -30.136 11.495  26.153  1   18.37  ? 80  PHE C CA  1 
ATOM   5189 C C   . PHE C 1 84  ? -29.795 12.557  25.124  1   18.97  ? 80  PHE C C   1 
ATOM   5190 O O   . PHE C 1 84  ? -28.744 13.18   25.223  1   21.66  ? 80  PHE C O   1 
ATOM   5191 C CB  . PHE C 1 84  ? -30.987 12.235  27.189  1   16.71  ? 80  PHE C CB  1 
ATOM   5192 C CG  . PHE C 1 84  ? -31.682 11.341  28.188  1   18.07  ? 80  PHE C CG  1 
ATOM   5193 C CD1 . PHE C 1 84  ? -32.942 10.816  27.91   1   19.49  ? 80  PHE C CD1 1 
ATOM   5194 C CD2 . PHE C 1 84  ? -31.071 11.034  29.396  1   18.47  ? 80  PHE C CD2 1 
ATOM   5195 C CE1 . PHE C 1 84  ? -33.594 10.025  28.842  1   18.78  ? 80  PHE C CE1 1 
ATOM   5196 C CE2 . PHE C 1 84  ? -31.717 10.229  30.307  1   18.39  ? 80  PHE C CE2 1 
ATOM   5197 C CZ  . PHE C 1 84  ? -32.975 9.73    30.031  1   18.51  ? 80  PHE C CZ  1 
ATOM   5198 N N   . GLU C 1 85  ? -30.702 12.786  24.18   1   19.22  ? 81  GLU C N   1 
ATOM   5199 C CA  . GLU C 1 85  ? -30.579 13.928  23.295  1   21.12  ? 81  GLU C CA  1 
ATOM   5200 C C   . GLU C 1 85  ? -30.624 15.185  24.165  1   23.22  ? 81  GLU C C   1 
ATOM   5201 O O   . GLU C 1 85  ? -31.359 15.242  25.147  1   26.26  ? 81  GLU C O   1 
ATOM   5202 C CB  . GLU C 1 85  ? -31.642 13.871  22.189  1   21.2   ? 81  GLU C CB  1 
ATOM   5203 C CG  . GLU C 1 85  ? -33.071 13.915  22.714  1   24.07  ? 81  GLU C CG  1 
ATOM   5204 C CD  . GLU C 1 85  ? -34.152 14.082  21.664  1   25.83  ? 81  GLU C CD  1 
ATOM   5205 O OE1 . GLU C 1 85  ? -34.073 14.984  20.819  1   27.04  ? 81  GLU C OE1 1 
ATOM   5206 O OE2 . GLU C 1 85  ? -35.125 13.322  21.725  1   28.99  ? 81  GLU C OE2 1 
ATOM   5207 N N   . PHE C 1 86  ? -29.827 16.192  23.81   1   23.73  ? 82  PHE C N   1 
ATOM   5208 C CA  . PHE C 1 86  ? -29.88  17.472  24.491  1   25.21  ? 82  PHE C CA  1 
ATOM   5209 C C   . PHE C 1 86  ? -30.954 18.336  23.852  1   26.93  ? 82  PHE C C   1 
ATOM   5210 O O   . PHE C 1 86  ? -30.951 18.561  22.648  1   26.83  ? 82  PHE C O   1 
ATOM   5211 C CB  . PHE C 1 86  ? -28.579 18.258  24.356  1   25.09  ? 82  PHE C CB  1 
ATOM   5212 C CG  . PHE C 1 86  ? -28.644 19.635  24.991  1   28.09  ? 82  PHE C CG  1 
ATOM   5213 C CD1 . PHE C 1 86  ? -28.525 19.772  26.379  1   28.8   ? 82  PHE C CD1 1 
ATOM   5214 C CD2 . PHE C 1 86  ? -28.793 20.784  24.206  1   27.6   ? 82  PHE C CD2 1 
ATOM   5215 C CE1 . PHE C 1 86  ? -28.58  21.027  26.98   1   28.45  ? 82  PHE C CE1 1 
ATOM   5216 C CE2 . PHE C 1 86  ? -28.832 22.044  24.803  1   27.05  ? 82  PHE C CE2 1 
ATOM   5217 C CZ  . PHE C 1 86  ? -28.734 22.162  26.188  1   29.16  ? 82  PHE C CZ  1 
ATOM   5218 N N   . LEU C 1 87  ? -31.818 18.88   24.701  1   30.67  ? 83  LEU C N   1 
ATOM   5219 C CA  . LEU C 1 87  ? -32.832 19.844  24.225  1   33.09  ? 83  LEU C CA  1 
ATOM   5220 C C   . LEU C 1 87  ? -32.602 21.146  25.01   1   34.73  ? 83  LEU C C   1 
ATOM   5221 O O   . LEU C 1 87  ? -32.386 21.048  26.22   1   32.44  ? 83  LEU C O   1 
ATOM   5222 C CB  . LEU C 1 87  ? -34.223 19.246  24.398  1   31.07  ? 83  LEU C CB  1 
ATOM   5223 C CG  . LEU C 1 87  ? -34.522 18.008  23.548  1   30.73  ? 83  LEU C CG  1 
ATOM   5224 C CD1 . LEU C 1 87  ? -35.868 17.421  23.911  1   32.46  ? 83  LEU C CD1 1 
ATOM   5225 C CD2 . LEU C 1 87  ? -34.461 18.323  22.068  1   28.93  ? 83  LEU C CD2 1 
ATOM   5226 N N   . HIS C 1 88  ? -32.645 22.303  24.351  1   37.39  ? 84  HIS C N   1 
ATOM   5227 C CA  . HIS C 1 88  ? -32.32  23.629  24.961  1   42.15  ? 84  HIS C CA  1 
ATOM   5228 C C   . HIS C 1 88  ? -32.948 23.923  26.332  1   38.58  ? 84  HIS C C   1 
ATOM   5229 O O   . HIS C 1 88  ? -32.199 24.405  27.197  1   37.14  ? 84  HIS C O   1 
ATOM   5230 C CB  . HIS C 1 88  ? -32.657 24.711  23.928  1   52.32  ? 84  HIS C CB  1 
ATOM   5231 C CG  . HIS C 1 88  ? -33.194 25.998  24.444  1   71.48  ? 84  HIS C CG  1 
ATOM   5232 N ND1 . HIS C 1 88  ? -32.429 26.926  25.114  1   87     ? 84  HIS C ND1 1 
ATOM   5233 C CD2 . HIS C 1 88  ? -34.418 26.524  24.35   1   87.16  ? 84  HIS C CD2 1 
ATOM   5234 C CE1 . HIS C 1 88  ? -33.185 27.967  25.429  1   95.21  ? 84  HIS C CE1 1 
ATOM   5235 N NE2 . HIS C 1 88  ? -34.396 27.744  24.971  1   99.62  ? 84  HIS C NE2 1 
ATOM   5236 N N   . GLN C 1 89  ? -34.24  23.676  26.541  1   34.18  ? 85  GLN C N   1 
ATOM   5237 C CA  . GLN C 1 89  ? -34.867 24.102  27.812  1   30.06  ? 85  GLN C CA  1 
ATOM   5238 C C   . GLN C 1 89  ? -36.154 23.349  28.129  1   26.76  ? 85  GLN C C   1 
ATOM   5239 O O   . GLN C 1 89  ? -36.672 22.679  27.234  1   26.01  ? 85  GLN C O   1 
ATOM   5240 C CB  . GLN C 1 89  ? -35.306 25.534  27.54   1   33.41  ? 85  GLN C CB  1 
ATOM   5241 C CG  . GLN C 1 89  ? -34.196 26.553  27.331  1   35.52  ? 85  GLN C CG  1 
ATOM   5242 C CD  . GLN C 1 89  ? -34.744 27.923  26.997  1   39.28  ? 85  GLN C CD  1 
ATOM   5243 O OE1 . GLN C 1 89  ? -35.854 28.069  26.477  1   45.72  ? 85  GLN C OE1 1 
ATOM   5244 N NE2 . GLN C 1 89  ? -33.965 28.949  27.301  1   38.47  ? 85  GLN C NE2 1 
ATOM   5245 N N   . ASP C 1 90  ? -36.645 23.464  29.366  1   25.1   ? 86  ASP C N   1 
ATOM   5246 C CA  . ASP C 1 90  ? -37.951 22.898  29.667  1   25.29  ? 86  ASP C CA  1 
ATOM   5247 C C   . ASP C 1 90  ? -39.06  23.942  29.47   1   25.15  ? 86  ASP C C   1 
ATOM   5248 O O   . ASP C 1 90  ? -38.775 25.121  29.323  1   23.64  ? 86  ASP C O   1 
ATOM   5249 C CB  . ASP C 1 90  ? -37.961 22.305  31.06   1   25.41  ? 86  ASP C CB  1 
ATOM   5250 C CG  . ASP C 1 90  ? -37.762 23.31   32.174  1   25.56  ? 86  ASP C CG  1 
ATOM   5251 O OD1 . ASP C 1 90  ? -38.701 24.038  32.495  1   26.26  ? 86  ASP C OD1 1 
ATOM   5252 O OD2 . ASP C 1 90  ? -36.652 23.349  32.689  1   32.85  ? 86  ASP C OD2 1 
ATOM   5253 N N   . LEU C 1 91  ? -40.328 23.504  29.471  1   24.48  ? 87  LEU C N   1 
ATOM   5254 C CA  . LEU C 1 91  ? -41.456 24.387  29.203  1   24.08  ? 87  LEU C CA  1 
ATOM   5255 C C   . LEU C 1 91  ? -41.625 25.382  30.35   1   24.84  ? 87  LEU C C   1 
ATOM   5256 O O   . LEU C 1 91  ? -42.008 26.53   30.135  1   27.03  ? 87  LEU C O   1 
ATOM   5257 C CB  . LEU C 1 91  ? -42.726 23.565  28.982  1   21.65  ? 87  LEU C CB  1 
ATOM   5258 C CG  . LEU C 1 91  ? -43.933 24.336  28.431  1   22.75  ? 87  LEU C CG  1 
ATOM   5259 C CD1 . LEU C 1 91  ? -43.618 24.81   27.015  1   22.16  ? 87  LEU C CD1 1 
ATOM   5260 C CD2 . LEU C 1 91  ? -45.214 23.479  28.434  1   19.65  ? 87  LEU C CD2 1 
ATOM   5261 N N   . LYS C 1 92  ? -41.345 24.931  31.573  1   24.31  ? 88  LYS C N   1 
ATOM   5262 C CA  . LYS C 1 92  ? -41.407 25.79   32.747  1   25.22  ? 88  LYS C CA  1 
ATOM   5263 C C   . LYS C 1 92  ? -40.444 26.966  32.577  1   24.3   ? 88  LYS C C   1 
ATOM   5264 O O   . LYS C 1 92  ? -40.805 28.118  32.803  1   24.32  ? 88  LYS C O   1 
ATOM   5265 C CB  . LYS C 1 92  ? -41.172 24.933  33.992  1   25.96  ? 88  LYS C CB  1 
ATOM   5266 C CG  . LYS C 1 92  ? -40.868 25.647  35.282  1   32.57  ? 88  LYS C CG  1 
ATOM   5267 C CD  . LYS C 1 92  ? -41.865 26.728  35.686  1   42.06  ? 88  LYS C CD  1 
ATOM   5268 C CE  . LYS C 1 92  ? -43.317 26.362  35.566  1   49.5   ? 88  LYS C CE  1 
ATOM   5269 N NZ  . LYS C 1 92  ? -44.154 27.422  36.143  1   53.69  ? 88  LYS C NZ  1 
ATOM   5270 N N   . LYS C 1 93  ? -39.229 26.683  32.112  1   23.98  ? 89  LYS C N   1 
ATOM   5271 C CA  . LYS C 1 93  ? -38.245 27.732  31.919  1   24.93  ? 89  LYS C CA  1 
ATOM   5272 C C   . LYS C 1 93  ? -38.718 28.699  30.834  1   22.08  ? 89  LYS C C   1 
ATOM   5273 O O   . LYS C 1 93  ? -38.613 29.916  31.01   1   20.23  ? 89  LYS C O   1 
ATOM   5274 C CB  . LYS C 1 93  ? -36.873 27.129  31.587  1   28.76  ? 89  LYS C CB  1 
ATOM   5275 C CG  . LYS C 1 93  ? -36.208 26.203  32.62   1   36.71  ? 89  LYS C CG  1 
ATOM   5276 C CD  . LYS C 1 93  ? -35.871 26.936  33.926  1   47.91  ? 89  LYS C CD  1 
ATOM   5277 C CE  . LYS C 1 93  ? -35.139 26.171  35.037  1   50.49  ? 89  LYS C CE  1 
ATOM   5278 N NZ  . LYS C 1 93  ? -34.829 26.848  36.298  1   47.62  ? 89  LYS C NZ  1 
ATOM   5279 N N   . PHE C 1 94  ? -39.21  28.139  29.715  1   20.7   ? 90  PHE C N   1 
ATOM   5280 C CA  . PHE C 1 94  ? -39.72  28.897  28.578  1   22.1   ? 90  PHE C CA  1 
ATOM   5281 C C   . PHE C 1 94  ? -40.87  29.839  28.982  1   24.71  ? 90  PHE C C   1 
ATOM   5282 O O   . PHE C 1 94  ? -40.785 31.059  28.754  1   23.97  ? 90  PHE C O   1 
ATOM   5283 C CB  . PHE C 1 94  ? -40.113 27.956  27.438  1   21.93  ? 90  PHE C CB  1 
ATOM   5284 C CG  . PHE C 1 94  ? -40.653 28.68   26.218  1   21.4   ? 90  PHE C CG  1 
ATOM   5285 C CD1 . PHE C 1 94  ? -39.847 29.572  25.516  1   21.39  ? 90  PHE C CD1 1 
ATOM   5286 C CD2 . PHE C 1 94  ? -41.969 28.488  25.795  1   20.66  ? 90  PHE C CD2 1 
ATOM   5287 C CE1 . PHE C 1 94  ? -40.347 30.241  24.404  1   21.24  ? 90  PHE C CE1 1 
ATOM   5288 C CE2 . PHE C 1 94  ? -42.465 29.159  24.687  1   19.85  ? 90  PHE C CE2 1 
ATOM   5289 C CZ  . PHE C 1 94  ? -41.649 30.031  23.994  1   21.03  ? 90  PHE C CZ  1 
ATOM   5290 N N   . MET C 1 95  ? -41.929 29.286  29.612  1   24.37  ? 91  MET C N   1 
ATOM   5291 C CA  . MET C 1 95  ? -43.035 30.095  30.138  1   24.78  ? 91  MET C CA  1 
ATOM   5292 C C   . MET C 1 95  ? -42.55  31.26   31.01   1   22.52  ? 91  MET C C   1 
ATOM   5293 O O   . MET C 1 95  ? -42.972 32.408  30.817  1   21.99  ? 91  MET C O   1 
ATOM   5294 C CB  . MET C 1 95  ? -44.018 29.24   30.935  1   24.21  ? 91  MET C CB  1 
ATOM   5295 C CG  . MET C 1 95  ? -44.765 28.284  30.056  1   29.07  ? 91  MET C CG  1 
ATOM   5296 S SD  . MET C 1 95  ? -46.105 27.38   30.859  1   41.24  ? 91  MET C SD  1 
ATOM   5297 C CE  . MET C 1 95  ? -45.266 26.17   31.897  1   32.66  ? 91  MET C CE  1 
ATOM   5298 N N   . ASP C 1 96  ? -41.674 30.942  31.973  1   21.55  ? 92  ASP C N   1 
ATOM   5299 C CA  . ASP C 1 96  ? -41.089 31.902  32.9    1   23.14  ? 92  ASP C CA  1 
ATOM   5300 C C   . ASP C 1 96  ? -40.39  33.031  32.144  1   23.7   ? 92  ASP C C   1 
ATOM   5301 O O   . ASP C 1 96  ? -40.552 34.207  32.496  1   22.1   ? 92  ASP C O   1 
ATOM   5302 C CB  . ASP C 1 96  ? -40.163 31.233  33.908  1   25.98  ? 92  ASP C CB  1 
ATOM   5303 C CG  . ASP C 1 96  ? -40.846 30.448  35.023  1   31.06  ? 92  ASP C CG  1 
ATOM   5304 O OD1 . ASP C 1 96  ? -42.099 30.476  35.085  1   31.71  ? 92  ASP C OD1 1 
ATOM   5305 O OD2 . ASP C 1 96  ? -40.126 29.794  35.819  1   34.7   ? 92  ASP C OD2 1 
ATOM   5306 N N   . ALA C 1 97  ? -39.619 32.664  31.103  1   24.22  ? 93  ALA C N   1 
ATOM   5307 C CA  . ALA C 1 97  ? -38.87  33.633  30.31   1   25.86  ? 93  ALA C CA  1 
ATOM   5308 C C   . ALA C 1 97  ? -39.814 34.458  29.44   1   25.59  ? 93  ALA C C   1 
ATOM   5309 O O   . ALA C 1 97  ? -39.485 35.58   29.059  1   24.5   ? 93  ALA C O   1 
ATOM   5310 C CB  . ALA C 1 97  ? -37.829 32.935  29.465  1   27.33  ? 93  ALA C CB  1 
ATOM   5311 N N   . SER C 1 98  ? -40.97  33.863  29.123  1   28.2   ? 94  SER C N   1 
ATOM   5312 C CA  . SER C 1 98  ? -42.018 34.475  28.324  1   33.02  ? 94  SER C CA  1 
ATOM   5313 C C   . SER C 1 98  ? -43.025 35.214  29.201  1   40.47  ? 94  SER C C   1 
ATOM   5314 O O   . SER C 1 98  ? -44.123 35.495  28.736  1   42.03  ? 94  SER C O   1 
ATOM   5315 C CB  . SER C 1 98  ? -42.725 33.43   27.499  1   30.08  ? 94  SER C CB  1 
ATOM   5316 O OG  . SER C 1 98  ? -41.888 32.926  26.467  1   29.9   ? 94  SER C OG  1 
ATOM   5317 N N   . ALA C 1 99  ? -42.651 35.512  30.456  1   47.62  ? 95  ALA C N   1 
ATOM   5318 C CA  . ALA C 1 99  ? -43.548 36.059  31.467  1   50.11  ? 95  ALA C CA  1 
ATOM   5319 C C   . ALA C 1 99  ? -44.189 37.365  30.999  1   50     ? 95  ALA C C   1 
ATOM   5320 O O   . ALA C 1 99  ? -45.395 37.548  31.134  1   52.84  ? 95  ALA C O   1 
ATOM   5321 C CB  . ALA C 1 99  ? -42.779 36.306  32.743  1   52.36  ? 95  ALA C CB  1 
ATOM   5322 N N   . LEU C 1 100 ? -43.371 38.26   30.45   1   44.11  ? 96  LEU C N   1 
ATOM   5323 C CA  . LEU C 1 100 ? -43.827 39.557  29.985  1   49.11  ? 96  LEU C CA  1 
ATOM   5324 C C   . LEU C 1 100 ? -44.382 39.479  28.558  1   55.58  ? 96  LEU C C   1 
ATOM   5325 O O   . LEU C 1 100 ? -45.536 39.855  28.346  1   61.5   ? 96  LEU C O   1 
ATOM   5326 C CB  . LEU C 1 100 ? -42.654 40.533  30.056  1   51.99  ? 96  LEU C CB  1 
ATOM   5327 C CG  . LEU C 1 100 ? -41.918 40.633  31.395  1   51.88  ? 96  LEU C CG  1 
ATOM   5328 C CD1 . LEU C 1 100 ? -40.889 41.774  31.345  1   48.48  ? 96  LEU C CD1 1 
ATOM   5329 C CD2 . LEU C 1 100 ? -42.89  40.778  32.556  1   49.55  ? 96  LEU C CD2 1 
ATOM   5330 N N   . THR C 1 101 ? -43.551 39.025  27.591  1   47.92  ? 97  THR C N   1 
ATOM   5331 C CA  . THR C 1 101 ? -43.883 38.963  26.167  1   41.95  ? 97  THR C CA  1 
ATOM   5332 C C   . THR C 1 101 ? -45.11  38.09   25.895  1   39.04  ? 97  THR C C   1 
ATOM   5333 O O   . THR C 1 101 ? -45.843 38.311  24.941  1   41.99  ? 97  THR C O   1 
ATOM   5334 C CB  . THR C 1 101 ? -42.713 38.499  25.29   1   41.92  ? 97  THR C CB  1 
ATOM   5335 O OG1 . THR C 1 101 ? -42.393 37.128  25.545  1   38.93  ? 97  THR C OG1 1 
ATOM   5336 C CG2 . THR C 1 101 ? -41.503 39.408  25.41   1   42.31  ? 97  THR C CG2 1 
ATOM   5337 N N   . GLY C 1 102 ? -45.324 37.058  26.697  1   38.04  ? 98  GLY C N   1 
ATOM   5338 C CA  . GLY C 1 102 ? -46.36  36.099  26.351  1   37.67  ? 98  GLY C CA  1 
ATOM   5339 C C   . GLY C 1 102 ? -45.895 35.115  25.277  1   34.71  ? 98  GLY C C   1 
ATOM   5340 O O   . GLY C 1 102 ? -44.843 35.303  24.669  1   33.12  ? 98  GLY C O   1 
ATOM   5341 N N   . ILE C 1 103 ? -46.705 34.067  25.074  1   31.2   ? 99  ILE C N   1 
ATOM   5342 C CA  . ILE C 1 103 ? -46.455 33.013  24.114  1   29.76  ? 99  ILE C CA  1 
ATOM   5343 C C   . ILE C 1 103 ? -47.504 33.091  23.007  1   30.47  ? 99  ILE C C   1 
ATOM   5344 O O   . ILE C 1 103 ? -48.704 33.031  23.262  1   33.39  ? 99  ILE C O   1 
ATOM   5345 C CB  . ILE C 1 103 ? -46.555 31.659  24.826  1   30.84  ? 99  ILE C CB  1 
ATOM   5346 C CG1 . ILE C 1 103 ? -45.714 31.599  26.095  1   33.12  ? 99  ILE C CG1 1 
ATOM   5347 C CG2 . ILE C 1 103 ? -46.247 30.508  23.866  1   29.19  ? 99  ILE C CG2 1 
ATOM   5348 C CD1 . ILE C 1 103 ? -45.85  30.269  26.83   1   32.63  ? 99  ILE C CD1 1 
ATOM   5349 N N   . PRO C 1 104 ? -47.111 33.208  21.724  1   29.68  ? 100 PRO C N   1 
ATOM   5350 C CA  . PRO C 1 104 ? -48.094 33.193  20.645  1   29.38  ? 100 PRO C CA  1 
ATOM   5351 C C   . PRO C 1 104 ? -49.012 31.972  20.667  1   28.93  ? 100 PRO C C   1 
ATOM   5352 O O   . PRO C 1 104 ? -48.593 30.854  20.949  1   27.36  ? 100 PRO C O   1 
ATOM   5353 C CB  . PRO C 1 104 ? -47.202 33.282  19.384  1   28.77  ? 100 PRO C CB  1 
ATOM   5354 C CG  . PRO C 1 104 ? -45.982 34.036  19.862  1   27.86  ? 100 PRO C CG  1 
ATOM   5355 C CD  . PRO C 1 104 ? -45.738 33.434  21.244  1   29.61  ? 100 PRO C CD  1 
ATOM   5356 N N   . LEU C 1 105 ? -50.276 32.212  20.315  1   33.47  ? 101 LEU C N   1 
ATOM   5357 C CA  . LEU C 1 105 ? -51.314 31.193  20.211  1   36.48  ? 101 LEU C CA  1 
ATOM   5358 C C   . LEU C 1 105 ? -50.906 30.029  19.297  1   31.61  ? 101 LEU C C   1 
ATOM   5359 O O   . LEU C 1 105 ? -51.096 28.868  19.665  1   34.57  ? 101 LEU C O   1 
ATOM   5360 C CB  . LEU C 1 105 ? -52.64  31.83   19.787  1   39.8   ? 101 LEU C CB  1 
ATOM   5361 C CG  . LEU C 1 105 ? -53.919 31.09   20.208  1   46.51  ? 101 LEU C CG  1 
ATOM   5362 C CD1 . LEU C 1 105 ? -54.124 29.783  19.439  1   47.03  ? 101 LEU C CD1 1 
ATOM   5363 C CD2 . LEU C 1 105 ? -53.974 30.849  21.723  1   44.66  ? 101 LEU C CD2 1 
ATOM   5364 N N   . PRO C 1 106 ? -50.359 30.258  18.08   1   27.72  ? 102 PRO C N   1 
ATOM   5365 C CA  . PRO C 1 106 ? -49.979 29.146  17.209  1   26.46  ? 102 PRO C CA  1 
ATOM   5366 C C   . PRO C 1 106 ? -48.939 28.213  17.838  1   24.24  ? 102 PRO C C   1 
ATOM   5367 O O   . PRO C 1 106 ? -48.997 27.003  17.624  1   22.63  ? 102 PRO C O   1 
ATOM   5368 C CB  . PRO C 1 106 ? -49.497 29.781  15.873  1   24.6   ? 102 PRO C CB  1 
ATOM   5369 C CG  . PRO C 1 106 ? -49.789 31.259  15.997  1   22.79  ? 102 PRO C CG  1 
ATOM   5370 C CD  . PRO C 1 106 ? -50.069 31.567  17.465  1   26.41  ? 102 PRO C CD  1 
ATOM   5371 N N   . LEU C 1 107 ? -47.997 28.786  18.604  1   23.26  ? 103 LEU C N   1 
ATOM   5372 C CA  . LEU C 1 107 ? -46.973 28.015  19.292  1   23.33  ? 103 LEU C CA  1 
ATOM   5373 C C   . LEU C 1 107 ? -47.588 27.151  20.401  1   23.62  ? 103 LEU C C   1 
ATOM   5374 O O   . LEU C 1 107 ? -47.267 25.964  20.507  1   23.06  ? 103 LEU C O   1 
ATOM   5375 C CB  . LEU C 1 107 ? -45.829 28.887  19.812  1   22.33  ? 103 LEU C CB  1 
ATOM   5376 C CG  . LEU C 1 107 ? -44.581 28.106  20.244  1   21.14  ? 103 LEU C CG  1 
ATOM   5377 C CD1 . LEU C 1 107 ? -43.846 27.521  19.04   1   20.37  ? 103 LEU C CD1 1 
ATOM   5378 C CD2 . LEU C 1 107 ? -43.652 28.961  21.095  1   20.84  ? 103 LEU C CD2 1 
ATOM   5379 N N   . ILE C 1 108 ? -48.498 27.745  21.197  1   24.61  ? 104 ILE C N   1 
ATOM   5380 C CA  . ILE C 1 108 ? -49.264 26.994  22.188  1   24.28  ? 104 ILE C CA  1 
ATOM   5381 C C   . ILE C 1 108 ? -49.936 25.791  21.52   1   26.91  ? 104 ILE C C   1 
ATOM   5382 O O   . ILE C 1 108 ? -49.778 24.633  21.947  1   28.7   ? 104 ILE C O   1 
ATOM   5383 C CB  . ILE C 1 108 ? -50.296 27.873  22.916  1   21.9   ? 104 ILE C CB  1 
ATOM   5384 C CG1 . ILE C 1 108 ? -49.646 29.021  23.675  1   21.81  ? 104 ILE C CG1 1 
ATOM   5385 C CG2 . ILE C 1 108 ? -51.16  27.016  23.846  1   20.23  ? 104 ILE C CG2 1 
ATOM   5386 C CD1 . ILE C 1 108 ? -50.623 29.889  24.452  1   20.95  ? 104 ILE C CD1 1 
ATOM   5387 N N   . LYS C 1 109 ? -50.689 26.077  20.453  1   25.9   ? 105 LYS C N   1 
ATOM   5388 C CA  . LYS C 1 109 ? -51.481 25.04   19.81   1   25.98  ? 105 LYS C CA  1 
ATOM   5389 C C   . LYS C 1 109 ? -50.568 23.956  19.235  1   23.86  ? 105 LYS C C   1 
ATOM   5390 O O   . LYS C 1 109 ? -50.94  22.781  19.22   1   21.15  ? 105 LYS C O   1 
ATOM   5391 C CB  . LYS C 1 109 ? -52.351 25.688  18.726  1   27.66  ? 105 LYS C CB  1 
ATOM   5392 C CG  . LYS C 1 109 ? -53.236 24.754  17.917  1   27.31  ? 105 LYS C CG  1 
ATOM   5393 C CD  . LYS C 1 109 ? -53.859 25.509  16.756  1   28.88  ? 105 LYS C CD  1 
ATOM   5394 C CE  . LYS C 1 109 ? -54.664 26.704  17.186  1   27.6   ? 105 LYS C CE  1 
ATOM   5395 N NZ  . LYS C 1 109 ? -55.896 26.804  16.41   1   25.54  ? 105 LYS C NZ  1 
ATOM   5396 N N   . SER C 1 110 ? -49.398 24.37   18.715  1   23.17  ? 106 SER C N   1 
ATOM   5397 C CA  . SER C 1 110 ? -48.439 23.427  18.173  1   24.41  ? 106 SER C CA  1 
ATOM   5398 C C   . SER C 1 110 ? -47.942 22.522  19.302  1   25.52  ? 106 SER C C   1 
ATOM   5399 O O   . SER C 1 110 ? -47.931 21.294  19.16   1   24.79  ? 106 SER C O   1 
ATOM   5400 C CB  . SER C 1 110 ? -47.305 24.143  17.485  1   25.67  ? 106 SER C CB  1 
ATOM   5401 O OG  . SER C 1 110 ? -46.235 23.25   17.182  1   29.78  ? 106 SER C OG  1 
ATOM   5402 N N   . TYR C 1 111 ? -47.551 23.155  20.424  1   23.6   ? 107 TYR C N   1 
ATOM   5403 C CA  . TYR C 1 111 ? -46.957 22.451  21.544  1   24.68  ? 107 TYR C CA  1 
ATOM   5404 C C   . TYR C 1 111 ? -47.942 21.42   22.098  1   26.85  ? 107 TYR C C   1 
ATOM   5405 O O   . TYR C 1 111 ? -47.565 20.269  22.341  1   30.79  ? 107 TYR C O   1 
ATOM   5406 C CB  . TYR C 1 111 ? -46.477 23.444  22.6    1   23.08  ? 107 TYR C CB  1 
ATOM   5407 C CG  . TYR C 1 111 ? -45.112 24.07   22.369  1   23.29  ? 107 TYR C CG  1 
ATOM   5408 C CD1 . TYR C 1 111 ? -44.267 23.655  21.337  1   22.04  ? 107 TYR C CD1 1 
ATOM   5409 C CD2 . TYR C 1 111 ? -44.653 25.065  23.233  1   22.79  ? 107 TYR C CD2 1 
ATOM   5410 C CE1 . TYR C 1 111 ? -43.006 24.215  21.189  1   23.41  ? 107 TYR C CE1 1 
ATOM   5411 C CE2 . TYR C 1 111 ? -43.406 25.645  23.073  1   23.57  ? 107 TYR C CE2 1 
ATOM   5412 C CZ  . TYR C 1 111 ? -42.572 25.208  22.061  1   25.45  ? 107 TYR C CZ  1 
ATOM   5413 O OH  . TYR C 1 111 ? -41.344 25.801  21.958  1   28.03  ? 107 TYR C OH  1 
ATOM   5414 N N   . LEU C 1 112 ? -49.201 21.829  22.299  1   25.49  ? 108 LEU C N   1 
ATOM   5415 C CA  . LEU C 1 112 ? -50.228 20.913  22.78   1   25.08  ? 108 LEU C CA  1 
ATOM   5416 C C   . LEU C 1 112 ? -50.384 19.745  21.808  1   23.5   ? 108 LEU C C   1 
ATOM   5417 O O   . LEU C 1 112 ? -50.485 18.593  22.215  1   22.28  ? 108 LEU C O   1 
ATOM   5418 C CB  . LEU C 1 112 ? -51.556 21.649  22.948  1   24.02  ? 108 LEU C CB  1 
ATOM   5419 C CG  . LEU C 1 112 ? -52.666 20.833  23.609  1   24.73  ? 108 LEU C CG  1 
ATOM   5420 C CD1 . LEU C 1 112 ? -52.237 20.468  25.031  1   24.59  ? 108 LEU C CD1 1 
ATOM   5421 C CD2 . LEU C 1 112 ? -53.981 21.602  23.626  1   24.6   ? 108 LEU C CD2 1 
ATOM   5422 N N   . PHE C 1 113 ? -50.427 20.059  20.513  1   25.63  ? 109 PHE C N   1 
ATOM   5423 C CA  . PHE C 1 113 ? -50.648 19.042  19.5    1   29.18  ? 109 PHE C CA  1 
ATOM   5424 C C   . PHE C 1 113 ? -49.534 17.995  19.565  1   30.23  ? 109 PHE C C   1 
ATOM   5425 O O   . PHE C 1 113 ? -49.79  16.781  19.488  1   29.11  ? 109 PHE C O   1 
ATOM   5426 C CB  . PHE C 1 113 ? -50.738 19.731  18.14   1   28.14  ? 109 PHE C CB  1 
ATOM   5427 C CG  . PHE C 1 113 ? -51.086 18.82   16.978  1   29.5   ? 109 PHE C CG  1 
ATOM   5428 C CD1 . PHE C 1 113 ? -52.333 18.205  16.913  1   30.27  ? 109 PHE C CD1 1 
ATOM   5429 C CD2 . PHE C 1 113 ? -50.185 18.627  15.926  1   32.34  ? 109 PHE C CD2 1 
ATOM   5430 C CE1 . PHE C 1 113 ? -52.677 17.407  15.828  1   31.01  ? 109 PHE C CE1 1 
ATOM   5431 C CE2 . PHE C 1 113 ? -50.524 17.816  14.846  1   33.19  ? 109 PHE C CE2 1 
ATOM   5432 C CZ  . PHE C 1 113 ? -51.768 17.206  14.799  1   32.86  ? 109 PHE C CZ  1 
ATOM   5433 N N   . GLN C 1 114 ? -48.295 18.474  19.712  1   28.64  ? 110 GLN C N   1 
ATOM   5434 C CA  . GLN C 1 114 ? -47.144 17.582  19.77   1   29.34  ? 110 GLN C CA  1 
ATOM   5435 C C   . GLN C 1 114 ? -47.184 16.763  21.06   1   27.17  ? 110 GLN C C   1 
ATOM   5436 O O   . GLN C 1 114 ? -46.916 15.569  21.033  1   25.93  ? 110 GLN C O   1 
ATOM   5437 C CB  . GLN C 1 114 ? -45.84  18.367  19.651  1   28.86  ? 110 GLN C CB  1 
ATOM   5438 C CG  . GLN C 1 114 ? -45.569 18.959  18.275  1   22.45  ? 110 GLN C CG  1 
ATOM   5439 C CD  . GLN C 1 114 ? -44.261 19.7    18.299  1   23.75  ? 110 GLN C CD  1 
ATOM   5440 O OE1 . GLN C 1 114 ? -43.189 19.114  18.473  1   26.56  ? 110 GLN C OE1 1 
ATOM   5441 N NE2 . GLN C 1 114 ? -44.348 21.016  18.223  1   24.78  ? 110 GLN C NE2 1 
ATOM   5442 N N   . LEU C 1 115 ? -47.542 17.406  22.18   1   26.69  ? 111 LEU C N   1 
ATOM   5443 C CA  . LEU C 1 115 ? -47.636 16.718  23.459  1   26.71  ? 111 LEU C CA  1 
ATOM   5444 C C   . LEU C 1 115 ? -48.673 15.597  23.389  1   29.12  ? 111 LEU C C   1 
ATOM   5445 O O   . LEU C 1 115 ? -48.49  14.535  23.986  1   27.63  ? 111 LEU C O   1 
ATOM   5446 C CB  . LEU C 1 115 ? -48.009 17.725  24.537  1   24.9   ? 111 LEU C CB  1 
ATOM   5447 C CG  . LEU C 1 115 ? -46.934 18.744  24.884  1   24.18  ? 111 LEU C CG  1 
ATOM   5448 C CD1 . LEU C 1 115 ? -47.455 19.679  25.951  1   22.61  ? 111 LEU C CD1 1 
ATOM   5449 C CD2 . LEU C 1 115 ? -45.713 18.01   25.368  1   23.75  ? 111 LEU C CD2 1 
ATOM   5450 N N   . LEU C 1 116 ? -49.777 15.841  22.672  1   27.2   ? 112 LEU C N   1 
ATOM   5451 C CA  . LEU C 1 116 ? -50.832 14.849  22.598  1   26.7   ? 112 LEU C CA  1 
ATOM   5452 C C   . LEU C 1 116 ? -50.389 13.704  21.701  1   29.36  ? 112 LEU C C   1 
ATOM   5453 O O   . LEU C 1 116 ? -50.786 12.557  21.915  1   30.54  ? 112 LEU C O   1 
ATOM   5454 C CB  . LEU C 1 116 ? -52.103 15.513  22.094  1   25.72  ? 112 LEU C CB  1 
ATOM   5455 C CG  . LEU C 1 116 ? -52.835 16.354  23.133  1   25.6   ? 112 LEU C CG  1 
ATOM   5456 C CD1 . LEU C 1 116 ? -53.709 17.355  22.413  1   26.51  ? 112 LEU C CD1 1 
ATOM   5457 C CD2 . LEU C 1 116 ? -53.648 15.472  24.08   1   24.41  ? 112 LEU C CD2 1 
ATOM   5458 N N   . GLN C 1 117 ? -49.553 14.018  20.704  1   31.24  ? 113 GLN C N   1 
ATOM   5459 C CA  . GLN C 1 117 ? -49.008 12.987  19.829  1   29.18  ? 113 GLN C CA  1 
ATOM   5460 C C   . GLN C 1 117 ? -48.069 12.071  20.602  1   28.09  ? 113 GLN C C   1 
ATOM   5461 O O   . GLN C 1 117 ? -48.178 10.849  20.512  1   29.63  ? 113 GLN C O   1 
ATOM   5462 C CB  . GLN C 1 117 ? -48.282 13.598  18.646  1   28     ? 113 GLN C CB  1 
ATOM   5463 C CG  . GLN C 1 117 ? -49.24  14.087  17.58   1   33.29  ? 113 GLN C CG  1 
ATOM   5464 C CD  . GLN C 1 117 ? -48.472 14.393  16.323  1   43.97  ? 113 GLN C CD  1 
ATOM   5465 O OE1 . GLN C 1 117 ? -48.265 13.511  15.485  1   53.54  ? 113 GLN C OE1 1 
ATOM   5466 N NE2 . GLN C 1 117 ? -47.947 15.606  16.233  1   50.48  ? 113 GLN C NE2 1 
ATOM   5467 N N   . GLY C 1 118 ? -47.16  12.672  21.372  1   26.09  ? 114 GLY C N   1 
ATOM   5468 C CA  . GLY C 1 118 ? -46.25  11.892  22.183  1   22.07  ? 114 GLY C CA  1 
ATOM   5469 C C   . GLY C 1 118 ? -47.029 11      23.137  1   22.19  ? 114 GLY C C   1 
ATOM   5470 O O   . GLY C 1 118 ? -46.682 9.828   23.329  1   23.76  ? 114 GLY C O   1 
ATOM   5471 N N   . LEU C 1 119 ? -48.067 11.583  23.742  1   22.05  ? 115 LEU C N   1 
ATOM   5472 C CA  . LEU C 1 119 ? -48.811 10.931  24.809  1   23.01  ? 115 LEU C CA  1 
ATOM   5473 C C   . LEU C 1 119 ? -49.681 9.793   24.267  1   24.11  ? 115 LEU C C   1 
ATOM   5474 O O   . LEU C 1 119 ? -49.715 8.72    24.875  1   26.94  ? 115 LEU C O   1 
ATOM   5475 C CB  . LEU C 1 119 ? -49.624 11.935  25.626  1   22.48  ? 115 LEU C CB  1 
ATOM   5476 C CG  . LEU C 1 119 ? -50.328 11.347  26.85   1   22.79  ? 115 LEU C CG  1 
ATOM   5477 C CD1 . LEU C 1 119 ? -49.317 10.897  27.883  1   23.93  ? 115 LEU C CD1 1 
ATOM   5478 C CD2 . LEU C 1 119 ? -51.295 12.318  27.465  1   23.4   ? 115 LEU C CD2 1 
ATOM   5479 N N   . ALA C 1 120 ? -50.379 10.031  23.144  1   22.43  ? 116 ALA C N   1 
ATOM   5480 C CA  . ALA C 1 120 ? -51.112 8.986   22.45   1   22.43  ? 116 ALA C CA  1 
ATOM   5481 C C   . ALA C 1 120 ? -50.2   7.796   22.163  1   24.43  ? 116 ALA C C   1 
ATOM   5482 O O   . ALA C 1 120 ? -50.577 6.645   22.395  1   26.45  ? 116 ALA C O   1 
ATOM   5483 C CB  . ALA C 1 120 ? -51.708 9.53    21.18   1   22.41  ? 116 ALA C CB  1 
ATOM   5484 N N   . PHE C 1 121 ? -48.988 8.076   21.665  1   25.35  ? 117 PHE C N   1 
ATOM   5485 C CA  . PHE C 1 121 ? -47.977 7.048   21.47   1   25.8   ? 117 PHE C CA  1 
ATOM   5486 C C   . PHE C 1 121 ? -47.701 6.276   22.767  1   27.7   ? 117 PHE C C   1 
ATOM   5487 O O   . PHE C 1 121 ? -47.642 5.051   22.738  1   34.12  ? 117 PHE C O   1 
ATOM   5488 C CB  . PHE C 1 121 ? -46.689 7.659   20.914  1   26.69  ? 117 PHE C CB  1 
ATOM   5489 C CG  . PHE C 1 121 ? -45.786 6.63    20.263  1   24.95  ? 117 PHE C CG  1 
ATOM   5490 C CD1 . PHE C 1 121 ? -44.873 5.907   21.03   1   27.36  ? 117 PHE C CD1 1 
ATOM   5491 C CD2 . PHE C 1 121 ? -45.882 6.359   18.9    1   24.11  ? 117 PHE C CD2 1 
ATOM   5492 C CE1 . PHE C 1 121 ? -44.06  4.94    20.435  1   26.5   ? 117 PHE C CE1 1 
ATOM   5493 C CE2 . PHE C 1 121 ? -45.079 5.385   18.311  1   24.16  ? 117 PHE C CE2 1 
ATOM   5494 C CZ  . PHE C 1 121 ? -44.167 4.68    19.075  1   24.61  ? 117 PHE C CZ  1 
ATOM   5495 N N   . CYS C 1 122 ? -47.53  6.963   23.907  1   26.06  ? 118 CYS C N   1 
ATOM   5496 C CA  . CYS C 1 122 ? -47.335 6.263   25.176  1   25.31  ? 118 CYS C CA  1 
ATOM   5497 C C   . CYS C 1 122 ? -48.496 5.341   25.495  1   24.73  ? 118 CYS C C   1 
ATOM   5498 O O   . CYS C 1 122 ? -48.269 4.188   25.836  1   26.31  ? 118 CYS C O   1 
ATOM   5499 C CB  . CYS C 1 122 ? -47.198 7.189   26.372  1   23.84  ? 118 CYS C CB  1 
ATOM   5500 S SG  . CYS C 1 122 ? -45.642 8.097   26.316  1   27.24  ? 118 CYS C SG  1 
ATOM   5501 N N   . HIS C 1 123 ? -49.717 5.874   25.403  1   26.6   ? 119 HIS C N   1 
ATOM   5502 C CA  . HIS C 1 123 ? -50.925 5.13    25.739  1   26.96  ? 119 HIS C CA  1 
ATOM   5503 C C   . HIS C 1 123 ? -51.085 3.921   24.819  1   25.76  ? 119 HIS C C   1 
ATOM   5504 O O   . HIS C 1 123 ? -51.426 2.85    25.307  1   24.68  ? 119 HIS C O   1 
ATOM   5505 C CB  . HIS C 1 123 ? -52.13  6.079   25.853  1   25.65  ? 119 HIS C CB  1 
ATOM   5506 C CG  . HIS C 1 123 ? -51.992 7.056   26.986  1   27.63  ? 119 HIS C CG  1 
ATOM   5507 N ND1 . HIS C 1 123 ? -52.727 8.222   27.078  1   25.79  ? 119 HIS C ND1 1 
ATOM   5508 C CD2 . HIS C 1 123 ? -51.205 7.023   28.088  1   27.47  ? 119 HIS C CD2 1 
ATOM   5509 C CE1 . HIS C 1 123 ? -52.396 8.856   28.193  1   26.63  ? 119 HIS C CE1 1 
ATOM   5510 N NE2 . HIS C 1 123 ? -51.47  8.155   28.816  1   28.37  ? 119 HIS C NE2 1 
ATOM   5511 N N   . SER C 1 124 ? -50.852 4.124   23.503  1   27.53  ? 120 SER C N   1 
ATOM   5512 C CA  . SER C 1 124 ? -50.889 3.103   22.459  1   26.64  ? 120 SER C CA  1 
ATOM   5513 C C   . SER C 1 124 ? -49.871 2       22.726  1   27.44  ? 120 SER C C   1 
ATOM   5514 O O   . SER C 1 124 ? -49.945 0.952   22.092  1   25.11  ? 120 SER C O   1 
ATOM   5515 C CB  . SER C 1 124 ? -50.616 3.703   21.111  1   27.66  ? 120 SER C CB  1 
ATOM   5516 O OG  . SER C 1 124 ? -51.688 4.543   20.711  1   36.19  ? 120 SER C OG  1 
ATOM   5517 N N   . HIS C 1 125 ? -48.904 2.258   23.625  1   28.85  ? 121 HIS C N   1 
ATOM   5518 C CA  . HIS C 1 125 ? -47.826 1.324   23.934  1   29.34  ? 121 HIS C CA  1 
ATOM   5519 C C   . HIS C 1 125 ? -47.825 0.991   25.422  1   27.17  ? 121 HIS C C   1 
ATOM   5520 O O   . HIS C 1 125 ? -46.784 0.635   25.959  1   26.85  ? 121 HIS C O   1 
ATOM   5521 C CB  . HIS C 1 125 ? -46.475 1.865   23.449  1   29.61  ? 121 HIS C CB  1 
ATOM   5522 C CG  . HIS C 1 125 ? -46.357 1.984   21.969  1   31.96  ? 121 HIS C CG  1 
ATOM   5523 N ND1 . HIS C 1 125 ? -47.102 2.867   21.225  1   34.74  ? 121 HIS C ND1 1 
ATOM   5524 C CD2 . HIS C 1 125 ? -45.603 1.318   21.076  1   35.92  ? 121 HIS C CD2 1 
ATOM   5525 C CE1 . HIS C 1 125 ? -46.787 2.746   19.933  1   34.04  ? 121 HIS C CE1 1 
ATOM   5526 N NE2 . HIS C 1 125 ? -45.872 1.817   19.819  1   33.19  ? 121 HIS C NE2 1 
ATOM   5527 N N   . ARG C 1 126 ? -48.952 0.931   26.061  1   28.18  ? 122 ARG C N   1 
ATOM   5528 C CA  . ARG C 1 126 ? -49.163 0.491   27.48   1   28.43  ? 122 ARG C CA  1 
ATOM   5529 C C   . ARG C 1 126 ? -48.257 1.188   28.511  1   29.55  ? 122 ARG C C   1 
ATOM   5530 O O   . ARG C 1 126 ? -47.934 0.551   29.511  1   30.47  ? 122 ARG C O   1 
ATOM   5531 C CB  . ARG C 1 126 ? -49.216 -1.041  27.598  1   27.18  ? 122 ARG C CB  1 
ATOM   5532 C CG  . ARG C 1 126 ? -48.12  -1.94   27.053  1   27.32  ? 122 ARG C CG  1 
ATOM   5533 C CD  . ARG C 1 126 ? -47.198 -2.332  28.182  1   26.89  ? 122 ARG C CD  1 
ATOM   5534 N NE  . ARG C 1 126 ? -46.078 -3.132  27.683  1   31.4   ? 122 ARG C NE  1 
ATOM   5535 C CZ  . ARG C 1 126 ? -45.064 -2.66   26.982  1   29.28  ? 122 ARG C CZ  1 
ATOM   5536 N NH1 . ARG C 1 126 ? -44.913 -1.359  26.83   1   26.91  ? 122 ARG C NH1 1 
ATOM   5537 N NH2 . ARG C 1 126 ? -44.202 -3.494  26.435  1   24.86  ? 122 ARG C NH2 1 
ATOM   5538 N N   . VAL C 1 127 ? -47.985 2.522   28.291  1   29.02  ? 123 VAL C N   1 
ATOM   5539 C CA  . VAL C 1 127 ? -47.172 3.273   29.245  1   26.38  ? 123 VAL C CA  1 
ATOM   5540 C C   . VAL C 1 127 ? -47.967 4.488   29.72   1   25.39  ? 123 VAL C C   1 
ATOM   5541 O O   . VAL C 1 127 ? -48.367 5.326   28.901  1   23.75  ? 123 VAL C O   1 
ATOM   5542 C CB  . VAL C 1 127 ? -45.82  3.744   28.655  1   26.59  ? 123 VAL C CB  1 
ATOM   5543 C CG1 . VAL C 1 127 ? -45.15  4.819   29.513  1   21.39  ? 123 VAL C CG1 1 
ATOM   5544 C CG2 . VAL C 1 127 ? -44.868 2.586   28.359  1   26.33  ? 123 VAL C CG2 1 
ATOM   5545 N N   . LEU C 1 128 ? -48.195 4.545   31.043  1   25.82  ? 124 LEU C N   1 
ATOM   5546 C CA  . LEU C 1 128 ? -48.606 5.757   31.745  1   25.18  ? 124 LEU C CA  1 
ATOM   5547 C C   . LEU C 1 128 ? -47.348 6.554   32.098  1   24.82  ? 124 LEU C C   1 
ATOM   5548 O O   . LEU C 1 128 ? -46.364 5.971   32.578  1   23.16  ? 124 LEU C O   1 
ATOM   5549 C CB  . LEU C 1 128 ? -49.382 5.418   33.017  1   24.88  ? 124 LEU C CB  1 
ATOM   5550 C CG  . LEU C 1 128 ? -50.738 4.717   32.885  1   27.73  ? 124 LEU C CG  1 
ATOM   5551 C CD1 . LEU C 1 128 ? -51.298 4.461   34.291  1   26.44  ? 124 LEU C CD1 1 
ATOM   5552 C CD2 . LEU C 1 128 ? -51.715 5.531   32.063  1   26.33  ? 124 LEU C CD2 1 
ATOM   5553 N N   . HIS C 1 129 ? -47.41  7.886   31.911  1   23.33  ? 125 HIS C N   1 
ATOM   5554 C CA  . HIS C 1 129 ? -46.289 8.763   32.225  1   24.38  ? 125 HIS C CA  1 
ATOM   5555 C C   . HIS C 1 129 ? -46.303 9.118   33.716  1   25.95  ? 125 HIS C C   1 
ATOM   5556 O O   . HIS C 1 129 ? -45.317 8.914   34.425  1   24.87  ? 125 HIS C O   1 
ATOM   5557 C CB  . HIS C 1 129 ? -46.323 10.031  31.365  1   23.2   ? 125 HIS C CB  1 
ATOM   5558 C CG  . HIS C 1 129 ? -45.093 10.875  31.502  1   24.86  ? 125 HIS C CG  1 
ATOM   5559 N ND1 . HIS C 1 129 ? -44.869 11.747  32.551  1   22.48  ? 125 HIS C ND1 1 
ATOM   5560 C CD2 . HIS C 1 129 ? -43.99  10.946  30.707  1   23.89  ? 125 HIS C CD2 1 
ATOM   5561 C CE1 . HIS C 1 129 ? -43.696 12.345  32.375  1   22.57  ? 125 HIS C CE1 1 
ATOM   5562 N NE2 . HIS C 1 129 ? -43.148 11.879  31.262  1   23.17  ? 125 HIS C NE2 1 
ATOM   5563 N N   . ARG C 1 130 ? -47.42  9.713   34.16   1   24.67  ? 126 ARG C N   1 
ATOM   5564 C CA  . ARG C 1 130 ? -47.719 9.931   35.567  1   23.87  ? 126 ARG C CA  1 
ATOM   5565 C C   . ARG C 1 130 ? -46.93  11.092  36.175  1   26.31  ? 126 ARG C C   1 
ATOM   5566 O O   . ARG C 1 130 ? -47.022 11.299  37.386  1   26.76  ? 126 ARG C O   1 
ATOM   5567 C CB  . ARG C 1 130 ? -47.496 8.65    36.375  1   21.64  ? 126 ARG C CB  1 
ATOM   5568 C CG  . ARG C 1 130 ? -48.393 7.5     35.933  1   19.04  ? 126 ARG C CG  1 
ATOM   5569 C CD  . ARG C 1 130 ? -48.465 6.44    37.001  1   18.67  ? 126 ARG C CD  1 
ATOM   5570 N NE  . ARG C 1 130 ? -47.145 5.883   37.298  1   18.99  ? 126 ARG C NE  1 
ATOM   5571 C CZ  . ARG C 1 130 ? -46.923 4.931   38.199  1   22.05  ? 126 ARG C CZ  1 
ATOM   5572 N NH1 . ARG C 1 130 ? -47.923 4.428   38.925  1   21.23  ? 126 ARG C NH1 1 
ATOM   5573 N NH2 . ARG C 1 130 ? -45.685 4.478   38.369  1   22.47  ? 126 ARG C NH2 1 
ATOM   5574 N N   . ASP C 1 131 ? -46.19  11.868  35.363  1   25.6   ? 127 ASP C N   1 
ATOM   5575 C CA  . ASP C 1 131 ? -45.48  13.017  35.909  1   26.74  ? 127 ASP C CA  1 
ATOM   5576 C C   . ASP C 1 131 ? -45.442 14.132  34.864  1   26.05  ? 127 ASP C C   1 
ATOM   5577 O O   . ASP C 1 131 ? -44.441 14.822  34.697  1   25.9   ? 127 ASP C O   1 
ATOM   5578 C CB  . ASP C 1 131 ? -44.125 12.634  36.501  1   27.51  ? 127 ASP C CB  1 
ATOM   5579 C CG  . ASP C 1 131 ? -43.554 13.584  37.55   1   28.39  ? 127 ASP C CG  1 
ATOM   5580 O OD1 . ASP C 1 131 ? -44.351 14.295  38.214  1   25.32  ? 127 ASP C OD1 1 
ATOM   5581 O OD2 . ASP C 1 131 ? -42.305 13.653  37.653  1   33.78  ? 127 ASP C OD2 1 
ATOM   5582 N N   . LEU C 1 132 ? -46.565 14.33   34.176  1   25.24  ? 128 LEU C N   1 
ATOM   5583 C CA  . LEU C 1 132 ? -46.587 15.345  33.144  1   24     ? 128 LEU C CA  1 
ATOM   5584 C C   . LEU C 1 132 ? -46.704 16.679  33.849  1   25.18  ? 128 LEU C C   1 
ATOM   5585 O O   . LEU C 1 132 ? -47.667 16.895  34.565  1   30.41  ? 128 LEU C O   1 
ATOM   5586 C CB  . LEU C 1 132 ? -47.713 15.12   32.134  1   22.12  ? 128 LEU C CB  1 
ATOM   5587 C CG  . LEU C 1 132 ? -47.615 13.834  31.3    1   22.91  ? 128 LEU C CG  1 
ATOM   5588 C CD1 . LEU C 1 132 ? -48.938 13.634  30.593  1   20.85  ? 128 LEU C CD1 1 
ATOM   5589 C CD2 . LEU C 1 132 ? -46.441 13.864  30.299  1   21.29  ? 128 LEU C CD2 1 
ATOM   5590 N N   . LYS C 1 133 ? -45.688 17.528  33.677  1   24.74  ? 129 LYS C N   1 
ATOM   5591 C CA  . LYS C 1 133 ? -45.696 18.893  34.172  1   25.12  ? 129 LYS C CA  1 
ATOM   5592 C C   . LYS C 1 133 ? -44.681 19.703  33.371  1   25.48  ? 129 LYS C C   1 
ATOM   5593 O O   . LYS C 1 133 ? -43.789 19.121  32.762  1   25.65  ? 129 LYS C O   1 
ATOM   5594 C CB  . LYS C 1 133 ? -45.347 18.912  35.662  1   25.08  ? 129 LYS C CB  1 
ATOM   5595 C CG  . LYS C 1 133 ? -44.104 18.11   36.007  1   26.23  ? 129 LYS C CG  1 
ATOM   5596 C CD  . LYS C 1 133 ? -43.866 18.127  37.512  1   28.16  ? 129 LYS C CD  1 
ATOM   5597 C CE  . LYS C 1 133 ? -42.551 17.495  37.804  1   26.6   ? 129 LYS C CE  1 
ATOM   5598 N NZ  . LYS C 1 133 ? -41.885 18.191  38.894  1   28.75  ? 129 LYS C NZ  1 
ATOM   5599 N N   . PRO C 1 134 ? -44.759 21.054  33.369  1   25.78  ? 130 PRO C N   1 
ATOM   5600 C CA  . PRO C 1 134 ? -43.92  21.872  32.492  1   24.9   ? 130 PRO C CA  1 
ATOM   5601 C C   . PRO C 1 134 ? -42.438 21.509  32.531  1   24.59  ? 130 PRO C C   1 
ATOM   5602 O O   . PRO C 1 134 ? -41.762 21.573  31.509  1   23.15  ? 130 PRO C O   1 
ATOM   5603 C CB  . PRO C 1 134 ? -44.164 23.304  32.984  1   26.73  ? 130 PRO C CB  1 
ATOM   5604 C CG  . PRO C 1 134 ? -45.529 23.265  33.622  1   28.32  ? 130 PRO C CG  1 
ATOM   5605 C CD  . PRO C 1 134 ? -45.656 21.862  34.216  1   27.59  ? 130 PRO C CD  1 
ATOM   5606 N N   . GLN C 1 135 ? -41.95  21.128  33.719  1   27.26  ? 131 GLN C N   1 
ATOM   5607 C CA  . GLN C 1 135 ? -40.529 20.886  33.967  1   28.47  ? 131 GLN C CA  1 
ATOM   5608 C C   . GLN C 1 135 ? -40.044 19.613  33.276  1   26.8   ? 131 GLN C C   1 
ATOM   5609 O O   . GLN C 1 135 ? -38.845 19.429  33.133  1   27.42  ? 131 GLN C O   1 
ATOM   5610 C CB  . GLN C 1 135 ? -40.206 20.674  35.445  1   28.53  ? 131 GLN C CB  1 
ATOM   5611 C CG  . GLN C 1 135 ? -40.362 21.904  36.334  1   32.65  ? 131 GLN C CG  1 
ATOM   5612 C CD  . GLN C 1 135 ? -41.773 22.208  36.812  1   36.63  ? 131 GLN C CD  1 
ATOM   5613 O OE1 . GLN C 1 135 ? -42.782 21.674  36.334  1   32.47  ? 131 GLN C OE1 1 
ATOM   5614 N NE2 . GLN C 1 135 ? -41.854 23.136  37.755  1   38.12  ? 131 GLN C NE2 1 
ATOM   5615 N N   . ASN C 1 136 ? -40.978 18.733  32.886  1   27.28  ? 132 ASN C N   1 
ATOM   5616 C CA  . ASN C 1 136 ? -40.693 17.428  32.299  1   23.67  ? 132 ASN C CA  1 
ATOM   5617 C C   . ASN C 1 136 ? -40.956 17.443  30.795  1   22.03  ? 132 ASN C C   1 
ATOM   5618 O O   . ASN C 1 136 ? -40.935 16.401  30.157  1   25.03  ? 132 ASN C O   1 
ATOM   5619 C CB  . ASN C 1 136 ? -41.457 16.31   33.018  1   21.8   ? 132 ASN C CB  1 
ATOM   5620 C CG  . ASN C 1 136 ? -40.963 16.065  34.432  1   22.24  ? 132 ASN C CG  1 
ATOM   5621 O OD1 . ASN C 1 136 ? -39.934 16.611  34.856  1   21.68  ? 132 ASN C OD1 1 
ATOM   5622 N ND2 . ASN C 1 136 ? -41.692 15.273  35.207  1   22.62  ? 132 ASN C ND2 1 
ATOM   5623 N N   . LEU C 1 137 ? -41.229 18.615  30.219  1   21.5   ? 133 LEU C N   1 
ATOM   5624 C CA  . LEU C 1 137 ? -41.438 18.734  28.788  1   20.32  ? 133 LEU C CA  1 
ATOM   5625 C C   . LEU C 1 137 ? -40.318 19.604  28.236  1   21.98  ? 133 LEU C C   1 
ATOM   5626 O O   . LEU C 1 137 ? -40.093 20.724  28.72   1   20.68  ? 133 LEU C O   1 
ATOM   5627 C CB  . LEU C 1 137 ? -42.802 19.351  28.513  1   20.46  ? 133 LEU C CB  1 
ATOM   5628 C CG  . LEU C 1 137 ? -43.962 18.741  29.304  1   21.82  ? 133 LEU C CG  1 
ATOM   5629 C CD1 . LEU C 1 137 ? -45.211 19.598  29.173  1   22.02  ? 133 LEU C CD1 1 
ATOM   5630 C CD2 . LEU C 1 137 ? -44.233 17.343  28.804  1   20.65  ? 133 LEU C CD2 1 
ATOM   5631 N N   . LEU C 1 138 ? -39.629 19.073  27.211  1   21.97  ? 134 LEU C N   1 
ATOM   5632 C CA  . LEU C 1 138 ? -38.464 19.756  26.672  1   22.81  ? 134 LEU C CA  1 
ATOM   5633 C C   . LEU C 1 138 ? -38.757 20.27   25.262  1   24.12  ? 134 LEU C C   1 
ATOM   5634 O O   . LEU C 1 138 ? -39.353 19.572  24.434  1   25.7   ? 134 LEU C O   1 
ATOM   5635 C CB  . LEU C 1 138 ? -37.287 18.786  26.676  1   23.17  ? 134 LEU C CB  1 
ATOM   5636 C CG  . LEU C 1 138 ? -37.071 17.987  27.966  1   24.79  ? 134 LEU C CG  1 
ATOM   5637 C CD1 . LEU C 1 138 ? -35.937 17.003  27.744  1   26.82  ? 134 LEU C CD1 1 
ATOM   5638 C CD2 . LEU C 1 138 ? -36.773 18.906  29.12   1   20.82  ? 134 LEU C CD2 1 
ATOM   5639 N N   . ILE C 1 139 ? -38.314 21.506  25.012  1   21.7   ? 135 ILE C N   1 
ATOM   5640 C CA  . ILE C 1 139 ? -38.42  22.158  23.728  1   20.99  ? 135 ILE C CA  1 
ATOM   5641 C C   . ILE C 1 139 ? -37.01  22.334  23.157  1   23.61  ? 135 ILE C C   1 
ATOM   5642 O O   . ILE C 1 139 ? -36.053 22.499  23.916  1   20.98  ? 135 ILE C O   1 
ATOM   5643 C CB  . ILE C 1 139 ? -39.087 23.528  23.942  1   20.88  ? 135 ILE C CB  1 
ATOM   5644 C CG1 . ILE C 1 139 ? -38.268 24.411  24.853  1   18.71  ? 135 ILE C CG1 1 
ATOM   5645 C CG2 . ILE C 1 139 ? -40.527 23.394  24.447  1   20.65  ? 135 ILE C CG2 1 
ATOM   5646 C CD1 . ILE C 1 139 ? -38.532 25.881  24.622  1   18.61  ? 135 ILE C CD1 1 
ATOM   5647 N N   . ASN C 1 140 ? -36.897 22.359  21.816  1   27.5   ? 136 ASN C N   1 
ATOM   5648 C CA  . ASN C 1 140 ? -35.682 22.812  21.133  1   30.95  ? 136 ASN C CA  1 
ATOM   5649 C C   . ASN C 1 140 ? -35.929 24.148  20.433  1   31.08  ? 136 ASN C C   1 
ATOM   5650 O O   . ASN C 1 140 ? -37.003 24.741  20.577  1   30.34  ? 136 ASN C O   1 
ATOM   5651 C CB  . ASN C 1 140 ? -35.098 21.784  20.163  1   30.89  ? 136 ASN C CB  1 
ATOM   5652 C CG  . ASN C 1 140 ? -36.026 21.372  19.03   1   32.47  ? 136 ASN C CG  1 
ATOM   5653 O OD1 . ASN C 1 140 ? -37.035 22.023  18.716  1   28.28  ? 136 ASN C OD1 1 
ATOM   5654 N ND2 . ASN C 1 140 ? -35.691 20.268  18.386  1   33.01  ? 136 ASN C ND2 1 
ATOM   5655 N N   . THR C 1 141 ? -34.923 24.588  19.66   1   31.03  ? 137 THR C N   1 
ATOM   5656 C CA  . THR C 1 141 ? -34.942 25.894  19.007  1   36.08  ? 137 THR C CA  1 
ATOM   5657 C C   . THR C 1 141 ? -35.837 25.898  17.767  1   36.14  ? 137 THR C C   1 
ATOM   5658 O O   . THR C 1 141 ? -36.112 26.958  17.213  1   38.78  ? 137 THR C O   1 
ATOM   5659 C CB  . THR C 1 141 ? -33.534 26.379  18.636  1   37.3   ? 137 THR C CB  1 
ATOM   5660 O OG1 . THR C 1 141 ? -33.026 25.49   17.648  1   39.55  ? 137 THR C OG1 1 
ATOM   5661 C CG2 . THR C 1 141 ? -32.574 26.462  19.812  1   37.52  ? 137 THR C CG2 1 
ATOM   5662 N N   . GLU C 1 142 ? -36.266 24.718  17.311  1   38.4   ? 138 GLU C N   1 
ATOM   5663 C CA  . GLU C 1 142 ? -36.958 24.602  16.032  1   40.16  ? 138 GLU C CA  1 
ATOM   5664 C C   . GLU C 1 142 ? -38.461 24.367  16.206  1   37.89  ? 138 GLU C C   1 
ATOM   5665 O O   . GLU C 1 142 ? -39.138 24.072  15.232  1   38.2   ? 138 GLU C O   1 
ATOM   5666 C CB  . GLU C 1 142 ? -36.312 23.486  15.212  1   42.32  ? 138 GLU C CB  1 
ATOM   5667 C CG  . GLU C 1 142 ? -34.79  23.595  15.197  1   52.69  ? 138 GLU C CG  1 
ATOM   5668 C CD  . GLU C 1 142 ? -34.157 23.425  13.829  1   64.49  ? 138 GLU C CD  1 
ATOM   5669 O OE1 . GLU C 1 142 ? -34.38  22.343  13.236  1   69.29  ? 138 GLU C OE1 1 
ATOM   5670 O OE2 . GLU C 1 142 ? -33.453 24.364  13.362  1   61.38  ? 138 GLU C OE2 1 
ATOM   5671 N N   . GLY C 1 143 ? -38.968 24.445  17.445  1   34.03  ? 139 GLY C N   1 
ATOM   5672 C CA  . GLY C 1 143 ? -40.398 24.449  17.711  1   30.31  ? 139 GLY C CA  1 
ATOM   5673 C C   . GLY C 1 143 ? -40.951 23.054  17.986  1   28.68  ? 139 GLY C C   1 
ATOM   5674 O O   . GLY C 1 143 ? -42.162 22.843  17.913  1   27.21  ? 139 GLY C O   1 
ATOM   5675 N N   . ALA C 1 144 ? -40.053 22.105  18.267  1   27.38  ? 140 ALA C N   1 
ATOM   5676 C CA  . ALA C 1 144 ? -40.445 20.79   18.754  1   26.38  ? 140 ALA C CA  1 
ATOM   5677 C C   . ALA C 1 144 ? -40.612 20.835  20.279  1   26.44  ? 140 ALA C C   1 
ATOM   5678 O O   . ALA C 1 144 ? -39.938 21.621  20.962  1   24.18  ? 140 ALA C O   1 
ATOM   5679 C CB  . ALA C 1 144 ? -39.41  19.763  18.326  1   21.71  ? 140 ALA C CB  1 
ATOM   5680 N N   . ILE C 1 145 ? -41.534 19.997  20.79   1   26.45  ? 141 ILE C N   1 
ATOM   5681 C CA  . ILE C 1 145 ? -41.641 19.699  22.216  1   26.92  ? 141 ILE C CA  1 
ATOM   5682 C C   . ILE C 1 145 ? -41.693 18.182  22.411  1   24.67  ? 141 ILE C C   1 
ATOM   5683 O O   . ILE C 1 145 ? -42.226 17.474  21.561  1   24.56  ? 141 ILE C O   1 
ATOM   5684 C CB  . ILE C 1 145 ? -42.866 20.396  22.841  1   26.49  ? 141 ILE C CB  1 
ATOM   5685 C CG1 . ILE C 1 145 ? -42.856 20.292  24.369  1   26.39  ? 141 ILE C CG1 1 
ATOM   5686 C CG2 . ILE C 1 145 ? -44.168 19.852  22.25   1   24.41  ? 141 ILE C CG2 1 
ATOM   5687 C CD1 . ILE C 1 145 ? -43.823 21.236  25.069  1   26.74  ? 141 ILE C CD1 1 
ATOM   5688 N N   . LYS C 1 146 ? -41.179 17.699  23.55   1   23.43  ? 142 LYS C N   1 
ATOM   5689 C CA  . LYS C 1 146 ? -41.042 16.265  23.807  1   22.04  ? 142 LYS C CA  1 
ATOM   5690 C C   . LYS C 1 146 ? -41.308 15.96   25.282  1   21.61  ? 142 LYS C C   1 
ATOM   5691 O O   . LYS C 1 146 ? -40.875 16.716  26.156  1   22.08  ? 142 LYS C O   1 
ATOM   5692 C CB  . LYS C 1 146 ? -39.638 15.764  23.451  1   20.72  ? 142 LYS C CB  1 
ATOM   5693 C CG  . LYS C 1 146 ? -39.246 16.064  22.014  1   21.29  ? 142 LYS C CG  1 
ATOM   5694 C CD  . LYS C 1 146 ? -38.017 15.315  21.536  1   20.49  ? 142 LYS C CD  1 
ATOM   5695 C CE  . LYS C 1 146 ? -37.508 15.768  20.198  1   20.9   ? 142 LYS C CE  1 
ATOM   5696 N NZ  . LYS C 1 146 ? -36.738 14.643  19.628  1   20.92  ? 142 LYS C NZ  1 
ATOM   5697 N N   . LEU C 1 147 ? -42.071 14.885  25.529  1   21.38  ? 143 LEU C N   1 
ATOM   5698 C CA  . LEU C 1 147 ? -42.233 14.313  26.852  1   22.45  ? 143 LEU C CA  1 
ATOM   5699 C C   . LEU C 1 147 ? -40.848 13.885  27.302  1   25.32  ? 143 LEU C C   1 
ATOM   5700 O O   . LEU C 1 147 ? -40.164 13.207  26.537  1   28.04  ? 143 LEU C O   1 
ATOM   5701 C CB  . LEU C 1 147 ? -43.098 13.054  26.823  1   21.77  ? 143 LEU C CB  1 
ATOM   5702 C CG  . LEU C 1 147 ? -44.474 13.134  26.155  1   25.19  ? 143 LEU C CG  1 
ATOM   5703 C CD1 . LEU C 1 147 ? -45.367 12.068  26.742  1   22.88  ? 143 LEU C CD1 1 
ATOM   5704 C CD2 . LEU C 1 147 ? -45.136 14.481  26.294  1   26.38  ? 143 LEU C CD2 1 
ATOM   5705 N N   . ALA C 1 148 ? -40.486 14.195  28.549  1   23.33  ? 144 ALA C N   1 
ATOM   5706 C CA  . ALA C 1 148 ? -39.258 13.664  29.126  1   25.74  ? 144 ALA C CA  1 
ATOM   5707 C C   . ALA C 1 148 ? -39.517 13.172  30.554  1   26.1   ? 144 ALA C C   1 
ATOM   5708 O O   . ALA C 1 148 ? -40.657 13.231  31.011  1   22.94  ? 144 ALA C O   1 
ATOM   5709 C CB  . ALA C 1 148 ? -38.188 14.731  29.075  1   25.24  ? 144 ALA C CB  1 
ATOM   5710 N N   . ASP C 1 149 ? -38.445 12.705  31.226  1   26.77  ? 145 ASP C N   1 
ATOM   5711 C CA  . ASP C 1 149 ? -38.416 12.168  32.583  1   26.82  ? 145 ASP C CA  1 
ATOM   5712 C C   . ASP C 1 149 ? -39.466 11.084  32.789  1   27.62  ? 145 ASP C C   1 
ATOM   5713 O O   . ASP C 1 149 ? -40.526 11.325  33.362  1   28.02  ? 145 ASP C O   1 
ATOM   5714 C CB  . ASP C 1 149 ? -38.514 13.223  33.672  1   31.08  ? 145 ASP C CB  1 
ATOM   5715 C CG  . ASP C 1 149 ? -38.013 12.78   35.043  1   39.56  ? 145 ASP C CG  1 
ATOM   5716 O OD1 . ASP C 1 149 ? -37.932 11.539  35.314  1   40.21  ? 145 ASP C OD1 1 
ATOM   5717 O OD2 . ASP C 1 149 ? -37.66  13.69   35.828  1   47.3   ? 145 ASP C OD2 1 
ATOM   5718 N N   . PHE C 1 150 ? -39.101 9.872   32.382  1   28.37  ? 146 PHE C N   1 
ATOM   5719 C CA  . PHE C 1 150 ? -39.98  8.724   32.428  1   24.66  ? 146 PHE C CA  1 
ATOM   5720 C C   . PHE C 1 150 ? -39.74  7.958   33.718  1   26.75  ? 146 PHE C C   1 
ATOM   5721 O O   . PHE C 1 150 ? -40.166 6.815   33.819  1   27.74  ? 146 PHE C O   1 
ATOM   5722 C CB  . PHE C 1 150 ? -39.767 7.893   31.162  1   24.94  ? 146 PHE C CB  1 
ATOM   5723 C CG  . PHE C 1 150 ? -40.639 8.381   30.021  1   24.25  ? 146 PHE C CG  1 
ATOM   5724 C CD1 . PHE C 1 150 ? -40.31  9.533   29.312  1   22.81  ? 146 PHE C CD1 1 
ATOM   5725 C CD2 . PHE C 1 150 ? -41.819 7.717   29.706  1   24.02  ? 146 PHE C CD2 1 
ATOM   5726 C CE1 . PHE C 1 150 ? -41.125 10.009  28.3    1   21.75  ? 146 PHE C CE1 1 
ATOM   5727 C CE2 . PHE C 1 150 ? -42.631 8.182   28.68   1   24.04  ? 146 PHE C CE2 1 
ATOM   5728 C CZ  . PHE C 1 150 ? -42.282 9.327   27.98   1   23.74  ? 146 PHE C CZ  1 
ATOM   5729 N N   . GLY C 1 151 ? -39.141 8.63    34.719  1   30.66  ? 147 GLY C N   1 
ATOM   5730 C CA  . GLY C 1 151 ? -38.766 8.044   36.007  1   32.41  ? 147 GLY C CA  1 
ATOM   5731 C C   . GLY C 1 151 ? -39.95  7.464   36.784  1   33.7   ? 147 GLY C C   1 
ATOM   5732 O O   . GLY C 1 151 ? -39.781 6.453   37.463  1   35.5   ? 147 GLY C O   1 
ATOM   5733 N N   . LEU C 1 152 ? -41.14  8.076   36.63   1   32.88  ? 148 LEU C N   1 
ATOM   5734 C CA  . LEU C 1 152 ? -42.346 7.652   37.322  1   32.56  ? 148 LEU C CA  1 
ATOM   5735 C C   . LEU C 1 152 ? -43.323 6.983   36.364  1   33.16  ? 148 LEU C C   1 
ATOM   5736 O O   . LEU C 1 152 ? -44.51  6.871   36.677  1   39.22  ? 148 LEU C O   1 
ATOM   5737 C CB  . LEU C 1 152 ? -43.021 8.871   37.941  1   36.66  ? 148 LEU C CB  1 
ATOM   5738 C CG  . LEU C 1 152 ? -42.278 9.612   39.049  1   42.24  ? 148 LEU C CG  1 
ATOM   5739 C CD1 . LEU C 1 152 ? -43.036 10.878  39.437  1   47.17  ? 148 LEU C CD1 1 
ATOM   5740 C CD2 . LEU C 1 152 ? -42.258 8.607   40.194  1   49.42  ? 148 LEU C CD2 1 
ATOM   5741 N N   . ALA C 1 153 ? -42.844 6.592   35.183  1   30.58  ? 149 ALA C N   1 
ATOM   5742 C CA  . ALA C 1 153 ? -43.689 5.903   34.219  1   26.84  ? 149 ALA C CA  1 
ATOM   5743 C C   . ALA C 1 153 ? -43.923 4.467   34.676  1   26.43  ? 149 ALA C C   1 
ATOM   5744 O O   . ALA C 1 153 ? -43.307 3.983   35.619  1   24.83  ? 149 ALA C O   1 
ATOM   5745 C CB  . ALA C 1 153 ? -43.068 5.952   32.841  1   24.47  ? 149 ALA C CB  1 
ATOM   5746 N N   . ARG C 1 154 ? -44.831 3.79    33.983  1   28.09  ? 150 ARG C N   1 
ATOM   5747 C CA  . ARG C 1 154 ? -45.296 2.485   34.415  1   29.54  ? 150 ARG C CA  1 
ATOM   5748 C C   . ARG C 1 154 ? -45.933 1.784   33.212  1   27.88  ? 150 ARG C C   1 
ATOM   5749 O O   . ARG C 1 154 ? -46.759 2.367   32.497  1   28.53  ? 150 ARG C O   1 
ATOM   5750 C CB  . ARG C 1 154 ? -46.17  2.713   35.662  1   29.45  ? 150 ARG C CB  1 
ATOM   5751 C CG  . ARG C 1 154 ? -47.272 1.684   35.86   1   32.12  ? 150 ARG C CG  1 
ATOM   5752 C CD  . ARG C 1 154 ? -46.823 0.375   36.46   1   34.2   ? 150 ARG C CD  1 
ATOM   5753 N NE  . ARG C 1 154 ? -46.689 0.382   37.924  1   30.18  ? 150 ARG C NE  1 
ATOM   5754 C CZ  . ARG C 1 154 ? -46.663 -0.742  38.629  1   27.79  ? 150 ARG C CZ  1 
ATOM   5755 N NH1 . ARG C 1 154 ? -46.576 -0.692  39.94   1   26.38  ? 150 ARG C NH1 1 
ATOM   5756 N NH2 . ARG C 1 154 ? -46.747 -1.917  38.022  1   26.39  ? 150 ARG C NH2 1 
ATOM   5757 N N   . ALA C 1 155 ? -45.493 0.551   32.951  1   25.32  ? 151 ALA C N   1 
ATOM   5758 C CA  . ALA C 1 155 ? -46.141 -0.219  31.906  1   25.35  ? 151 ALA C CA  1 
ATOM   5759 C C   . ALA C 1 155 ? -47.426 -0.784  32.508  1   27.41  ? 151 ALA C C   1 
ATOM   5760 O O   . ALA C 1 155 ? -47.374 -1.445  33.551  1   27.81  ? 151 ALA C O   1 
ATOM   5761 C CB  . ALA C 1 155 ? -45.195 -1.29   31.388  1   21.72  ? 151 ALA C CB  1 
ATOM   5762 N N   . PHE C 1 156 ? -48.579 -0.466  31.903  1   27.54  ? 152 PHE C N   1 
ATOM   5763 C CA  . PHE C 1 156 ? -49.847 -0.96   32.431  1   27.12  ? 152 PHE C CA  1 
ATOM   5764 C C   . PHE C 1 156 ? -50.369 -2.128  31.597  1   28.46  ? 152 PHE C C   1 
ATOM   5765 O O   . PHE C 1 156 ? -49.965 -2.326  30.448  1   31.68  ? 152 PHE C O   1 
ATOM   5766 C CB  . PHE C 1 156 ? -50.885 0.159   32.554  1   25.59  ? 152 PHE C CB  1 
ATOM   5767 C CG  . PHE C 1 156 ? -51.367 0.791   31.257  1   25.97  ? 152 PHE C CG  1 
ATOM   5768 C CD1 . PHE C 1 156 ? -52.479 0.289   30.57   1   27.21  ? 152 PHE C CD1 1 
ATOM   5769 C CD2 . PHE C 1 156 ? -50.735 1.921   30.749  1   26.56  ? 152 PHE C CD2 1 
ATOM   5770 C CE1 . PHE C 1 156 ? -52.945 0.901   29.408  1   26.33  ? 152 PHE C CE1 1 
ATOM   5771 C CE2 . PHE C 1 156 ? -51.196 2.529   29.584  1   26.77  ? 152 PHE C CE2 1 
ATOM   5772 C CZ  . PHE C 1 156 ? -52.304 2.022   28.919  1   25.63  ? 152 PHE C CZ  1 
ATOM   5773 N N   . GLY C 1 157 ? -51.283 -2.899  32.201  1   26.41  ? 153 GLY C N   1 
ATOM   5774 C CA  . GLY C 1 157 ? -52     -3.957  31.508  1   25.82  ? 153 GLY C CA  1 
ATOM   5775 C C   . GLY C 1 157 ? -53.472 -3.574  31.335  1   27.59  ? 153 GLY C C   1 
ATOM   5776 O O   . GLY C 1 157 ? -53.91  -2.576  31.913  1   29.33  ? 153 GLY C O   1 
ATOM   5777 N N   . VAL C 1 158 ? -54.214 -4.366  30.542  1   25.18  ? 154 VAL C N   1 
ATOM   5778 C CA  . VAL C 1 158 ? -55.573 -4.03   30.142  1   25.08  ? 154 VAL C CA  1 
ATOM   5779 C C   . VAL C 1 158 ? -56.488 -5.139  30.663  1   28.36  ? 154 VAL C C   1 
ATOM   5780 O O   . VAL C 1 158 ? -56.324 -6.294  30.257  1   32.13  ? 154 VAL C O   1 
ATOM   5781 C CB  . VAL C 1 158 ? -55.653 -3.903  28.605  1   23.59  ? 154 VAL C CB  1 
ATOM   5782 C CG1 . VAL C 1 158 ? -57.063 -3.578  28.114  1   21.71  ? 154 VAL C CG1 1 
ATOM   5783 C CG2 . VAL C 1 158 ? -54.615 -2.938  28.032  1   20.5   ? 154 VAL C CG2 1 
ATOM   5784 N N   . PRO C 1 159 ? -57.426 -4.877  31.617  1   27.4   ? 155 PRO C N   1 
ATOM   5785 C CA  . PRO C 1 159 ? -57.65  -3.547  32.2    1   26.34  ? 155 PRO C CA  1 
ATOM   5786 C C   . PRO C 1 159 ? -56.608 -3.206  33.263  1   27.64  ? 155 PRO C C   1 
ATOM   5787 O O   . PRO C 1 159 ? -55.871 -4.089  33.724  1   28.82  ? 155 PRO C O   1 
ATOM   5788 C CB  . PRO C 1 159 ? -59.026 -3.748  32.867  1   26.39  ? 155 PRO C CB  1 
ATOM   5789 C CG  . PRO C 1 159 ? -59.008 -5.178  33.373  1   25.4   ? 155 PRO C CG  1 
ATOM   5790 C CD  . PRO C 1 159 ? -58.271 -5.912  32.25   1   25.98  ? 155 PRO C CD  1 
ATOM   5791 N N   . VAL C 1 160 ? -56.577 -1.935  33.68   1   25.99  ? 156 VAL C N   1 
ATOM   5792 C CA  . VAL C 1 160 ? -55.567 -1.495  34.634  1   24.83  ? 156 VAL C CA  1 
ATOM   5793 C C   . VAL C 1 160 ? -55.819 -2.198  35.956  1   24.66  ? 156 VAL C C   1 
ATOM   5794 O O   . VAL C 1 160 ? -56.945 -2.622  36.217  1   25.87  ? 156 VAL C O   1 
ATOM   5795 C CB  . VAL C 1 160 ? -55.515 0.027   34.833  1   22.72  ? 156 VAL C CB  1 
ATOM   5796 C CG1 . VAL C 1 160 ? -55.144 0.745   33.54   1   23.53  ? 156 VAL C CG1 1 
ATOM   5797 C CG2 . VAL C 1 160 ? -56.812 0.566   35.408  1   20.94  ? 156 VAL C CG2 1 
ATOM   5798 N N   . ARG C 1 161 ? -54.757 -2.321  36.754  1   24.74  ? 157 ARG C N   1 
ATOM   5799 C CA  . ARG C 1 161 ? -54.88  -2.717  38.148  1   28.47  ? 157 ARG C CA  1 
ATOM   5800 C C   . ARG C 1 161 ? -54.396 -1.568  39.041  1   29.38  ? 157 ARG C C   1 
ATOM   5801 O O   . ARG C 1 161 ? -54.044 -0.494  38.544  1   28.84  ? 157 ARG C O   1 
ATOM   5802 C CB  . ARG C 1 161 ? -54.221 -4.081  38.4    1   29.61  ? 157 ARG C CB  1 
ATOM   5803 C CG  . ARG C 1 161 ? -52.702 -4.074  38.462  1   36.92  ? 157 ARG C CG  1 
ATOM   5804 C CD  . ARG C 1 161 ? -52.171 -5.309  39.175  1   43.64  ? 157 ARG C CD  1 
ATOM   5805 N NE  . ARG C 1 161 ? -50.967 -4.913  39.919  1   55.55  ? 157 ARG C NE  1 
ATOM   5806 C CZ  . ARG C 1 161 ? -49.74  -4.829  39.421  1   54.08  ? 157 ARG C CZ  1 
ATOM   5807 N NH1 . ARG C 1 161 ? -49.521 -5.255  38.189  1   49.87  ? 157 ARG C NH1 1 
ATOM   5808 N NH2 . ARG C 1 161 ? -48.758 -4.341  40.17   1   50.49  ? 157 ARG C NH2 1 
ATOM   5809 N N   . THR C 1 162 ? -54.385 -1.803  40.364  1   27.82  ? 158 THR C N   1 
ATOM   5810 C CA  . THR C 1 162 ? -53.948 -0.813  41.347  1   28.85  ? 158 THR C CA  1 
ATOM   5811 C C   . THR C 1 162 ? -52.441 -0.579  41.2    1   27.29  ? 158 THR C C   1 
ATOM   5812 O O   . THR C 1 162 ? -51.665 -1.539  41.289  1   26.91  ? 158 THR C O   1 
ATOM   5813 C CB  . THR C 1 162 ? -54.324 -1.296  42.752  1   30.18  ? 158 THR C CB  1 
ATOM   5814 O OG1 . THR C 1 162 ? -55.734 -1.493  42.693  1   38.3   ? 158 THR C OG1 1 
ATOM   5815 C CG2 . THR C 1 162 ? -53.977 -0.318  43.861  1   25.57  ? 158 THR C CG2 1 
ATOM   5816 N N   . TYR C 1 163 ? -52.055 0.697   40.99   1   25.61  ? 159 TYR C N   1 
ATOM   5817 C CA  . TYR C 1 163 ? -50.667 1.126   40.916  1   26.13  ? 159 TYR C CA  1 
ATOM   5818 C C   . TYR C 1 163 ? -50.361 2.044   42.099  1   30.89  ? 159 TYR C C   1 
ATOM   5819 O O   . TYR C 1 163 ? -51.21  2.195   42.976  1   35     ? 159 TYR C O   1 
ATOM   5820 C CB  . TYR C 1 163 ? -50.423 1.763   39.547  1   26.53  ? 159 TYR C CB  1 
ATOM   5821 C CG  . TYR C 1 163 ? -50.782 0.844   38.388  1   26.88  ? 159 TYR C CG  1 
ATOM   5822 C CD1 . TYR C 1 163 ? -50.384 -0.489  38.39   1   28.87  ? 159 TYR C CD1 1 
ATOM   5823 C CD2 . TYR C 1 163 ? -51.53  1.299   37.314  1   23.66  ? 159 TYR C CD2 1 
ATOM   5824 C CE1 . TYR C 1 163 ? -50.691 -1.336  37.338  1   30.33  ? 159 TYR C CE1 1 
ATOM   5825 C CE2 . TYR C 1 163 ? -51.855 0.461   36.267  1   27.28  ? 159 TYR C CE2 1 
ATOM   5826 C CZ  . TYR C 1 163 ? -51.437 -0.866  36.269  1   32.01  ? 159 TYR C CZ  1 
ATOM   5827 O OH  . TYR C 1 163 ? -51.774 -1.756  35.261  1   34     ? 159 TYR C OH  1 
HETATM 5828 N N   . TPO C 1 164 ? -49.143 2.628   42.138  1   28.98  ? 160 TPO C N   1 
HETATM 5829 C CA  . TPO C 1 164 ? -48.726 3.53    43.205  1   27.93  ? 160 TPO C CA  1 
HETATM 5830 C CB  . TPO C 1 164 ? -47.271 3.966   42.976  1   28     ? 160 TPO C CB  1 
HETATM 5831 C CG2 . TPO C 1 164 ? -46.705 4.776   44.121  1   28.71  ? 160 TPO C CG2 1 
HETATM 5832 O OG1 . TPO C 1 164 ? -46.451 2.759   42.836  1   25.61  ? 160 TPO C OG1 1 
HETATM 5833 P P   . TPO C 1 164 ? -45.814 2.367   41.399  1   24.4   ? 160 TPO C P   1 
HETATM 5834 O O1P . TPO C 1 164 ? -46.955 2.122   40.458  1   25.73  ? 160 TPO C O1P 1 
HETATM 5835 O O2P . TPO C 1 164 ? -44.974 1.141   41.66   1   23.68  ? 160 TPO C O2P 1 
HETATM 5836 O O3P . TPO C 1 164 ? -45.012 3.545   40.929  1   23.85  ? 160 TPO C O3P 1 
HETATM 5837 C C   . TPO C 1 164 ? -49.651 4.754   43.263  1   29.71  ? 160 TPO C C   1 
HETATM 5838 O O   . TPO C 1 164 ? -50.004 5.318   42.223  1   28.24  ? 160 TPO C O   1 
ATOM   5839 N N   . HIS C 1 165 ? -50.007 5.19    44.481  1   33.72  ? 161 HIS C N   1 
ATOM   5840 C CA  . HIS C 1 165 ? -50.909 6.325   44.652  1   40.35  ? 161 HIS C CA  1 
ATOM   5841 C C   . HIS C 1 165 ? -50.152 7.66    44.671  1   44.19  ? 161 HIS C C   1 
ATOM   5842 O O   . HIS C 1 165 ? -50.667 8.701   44.245  1   41.21  ? 161 HIS C O   1 
ATOM   5843 C CB  . HIS C 1 165 ? -51.809 6.1     45.87   1   45.61  ? 161 HIS C CB  1 
ATOM   5844 C CG  . HIS C 1 165 ? -52.486 7.342   46.337  1   65.26  ? 161 HIS C CG  1 
ATOM   5845 N ND1 . HIS C 1 165 ? -51.83  8.293   47.098  1   71.56  ? 161 HIS C ND1 1 
ATOM   5846 C CD2 . HIS C 1 165 ? -53.735 7.805   46.148  1   70.95  ? 161 HIS C CD2 1 
ATOM   5847 C CE1 . HIS C 1 165 ? -52.669 9.284   47.374  1   76.34  ? 161 HIS C CE1 1 
ATOM   5848 N NE2 . HIS C 1 165 ? -53.834 9.002   46.819  1   77.22  ? 161 HIS C NE2 1 
ATOM   5849 N N   . GLU C 1 166 ? -48.917 7.635   45.192  1   51.88  ? 162 GLU C N   1 
ATOM   5850 C CA  . GLU C 1 166 ? -48.097 8.84    45.274  1   54.57  ? 162 GLU C CA  1 
ATOM   5851 C C   . GLU C 1 166 ? -47.586 9.156   43.866  1   53.06  ? 162 GLU C C   1 
ATOM   5852 O O   . GLU C 1 166 ? -46.401 8.984   43.565  1   58.6   ? 162 GLU C O   1 
ATOM   5853 C CB  . GLU C 1 166 ? -46.918 8.755   46.256  1   56.79  ? 162 GLU C CB  1 
ATOM   5854 C CG  . GLU C 1 166 ? -47.232 8.323   47.691  1   59.7   ? 162 GLU C CG  1 
ATOM   5855 C CD  . GLU C 1 166 ? -48.05  7.048   47.915  1   67.29  ? 162 GLU C CD  1 
ATOM   5856 O OE1 . GLU C 1 166 ? -47.861 6.009   47.22   1   64.27  ? 162 GLU C OE1 1 
ATOM   5857 O OE2 . GLU C 1 166 ? -48.91  7.102   48.828  1   67.19  ? 162 GLU C OE2 1 
ATOM   5858 N N   . VAL C 1 167 ? -48.489 9.602   42.988  1   42.83  ? 163 VAL C N   1 
ATOM   5859 C CA  . VAL C 1 167 ? -48.108 9.824   41.599  1   44.28  ? 163 VAL C CA  1 
ATOM   5860 C C   . VAL C 1 167 ? -48.585 11.218  41.194  1   37.93  ? 163 VAL C C   1 
ATOM   5861 O O   . VAL C 1 167 ? -49.622 11.674  41.69   1   32.65  ? 163 VAL C O   1 
ATOM   5862 C CB  . VAL C 1 167 ? -48.633 8.742   40.625  1   43.64  ? 163 VAL C CB  1 
ATOM   5863 C CG1 . VAL C 1 167 ? -47.862 7.429   40.735  1   37.02  ? 163 VAL C CG1 1 
ATOM   5864 C CG2 . VAL C 1 167 ? -50.127 8.507   40.809  1   44.42  ? 163 VAL C CG2 1 
ATOM   5865 N N   . VAL C 1 168 ? -47.815 11.865  40.302  1   31.38  ? 164 VAL C N   1 
ATOM   5866 C CA  . VAL C 1 168 ? -48.183 13.159  39.738  1   31.08  ? 164 VAL C CA  1 
ATOM   5867 C C   . VAL C 1 168 ? -47.908 14.254  40.783  1   30.65  ? 164 VAL C C   1 
ATOM   5868 O O   . VAL C 1 168 ? -48.401 14.21   41.906  1   31.12  ? 164 VAL C O   1 
ATOM   5869 C CB  . VAL C 1 168 ? -49.616 13.275  39.141  1   27.94  ? 164 VAL C CB  1 
ATOM   5870 C CG1 . VAL C 1 168 ? -49.753 14.507  38.266  1   24.66  ? 164 VAL C CG1 1 
ATOM   5871 C CG2 . VAL C 1 168 ? -50.103 12.045  38.359  1   25.05  ? 164 VAL C CG2 1 
ATOM   5872 N N   . THR C 1 169 ? -47.118 15.264  40.411  1   32.75  ? 165 THR C N   1 
ATOM   5873 C CA  . THR C 1 169 ? -46.97  16.461  41.234  1   33.41  ? 165 THR C CA  1 
ATOM   5874 C C   . THR C 1 169 ? -48.36  17.037  41.521  1   30.34  ? 165 THR C C   1 
ATOM   5875 O O   . THR C 1 169 ? -49.196 17.117  40.616  1   33.59  ? 165 THR C O   1 
ATOM   5876 C CB  . THR C 1 169 ? -46.101 17.478  40.483  1   36.26  ? 165 THR C CB  1 
ATOM   5877 O OG1 . THR C 1 169 ? -44.944 16.763  40.064  1   42.27  ? 165 THR C OG1 1 
ATOM   5878 C CG2 . THR C 1 169 ? -45.742 18.687  41.329  1   35.26  ? 165 THR C CG2 1 
ATOM   5879 N N   . LEU C 1 170 ? -48.567 17.494  42.76   1   26.78  ? 166 LEU C N   1 
ATOM   5880 C CA  . LEU C 1 170 ? -49.873 17.898  43.263  1   25.96  ? 166 LEU C CA  1 
ATOM   5881 C C   . LEU C 1 170 ? -50.676 18.719  42.239  1   27.6   ? 166 LEU C C   1 
ATOM   5882 O O   . LEU C 1 170 ? -51.829 18.402  41.936  1   29.51  ? 166 LEU C O   1 
ATOM   5883 C CB  . LEU C 1 170 ? -49.673 18.655  44.578  1   23     ? 166 LEU C CB  1 
ATOM   5884 C CG  . LEU C 1 170 ? -50.953 19.045  45.324  1   23.91  ? 166 LEU C CG  1 
ATOM   5885 C CD1 . LEU C 1 170 ? -51.888 17.862  45.556  1   21.38  ? 166 LEU C CD1 1 
ATOM   5886 C CD2 . LEU C 1 170 ? -50.609 19.709  46.64   1   21.28  ? 166 LEU C CD2 1 
ATOM   5887 N N   . TRP C 1 171 ? -50.067 19.783  41.706  1   25.45  ? 167 TRP C N   1 
ATOM   5888 C CA  . TRP C 1 171 ? -50.784 20.74   40.879  1   24.06  ? 167 TRP C CA  1 
ATOM   5889 C C   . TRP C 1 171 ? -51.401 20.096  39.635  1   23.16  ? 167 TRP C C   1 
ATOM   5890 O O   . TRP C 1 171 ? -52.316 20.681  39.069  1   23.5   ? 167 TRP C O   1 
ATOM   5891 C CB  . TRP C 1 171 ? -49.871 21.896  40.459  1   22.3   ? 167 TRP C CB  1 
ATOM   5892 C CG  . TRP C 1 171 ? -49.412 22.793  41.571  1   25.19  ? 167 TRP C CG  1 
ATOM   5893 C CD1 . TRP C 1 171 ? -49.778 22.758  42.887  1   27.17  ? 167 TRP C CD1 1 
ATOM   5894 C CD2 . TRP C 1 171 ? -48.535 23.929  41.429  1   24.95  ? 167 TRP C CD2 1 
ATOM   5895 N NE1 . TRP C 1 171 ? -49.171 23.772  43.574  1   23.96  ? 167 TRP C NE1 1 
ATOM   5896 C CE2 . TRP C 1 171 ? -48.411 24.512  42.709  1   25.14  ? 167 TRP C CE2 1 
ATOM   5897 C CE3 . TRP C 1 171 ? -47.853 24.503  40.351  1   25.14  ? 167 TRP C CE3 1 
ATOM   5898 C CZ2 . TRP C 1 171 ? -47.632 25.648  42.937  1   27.46  ? 167 TRP C CZ2 1 
ATOM   5899 C CZ3 . TRP C 1 171 ? -47.091 25.628  40.576  1   27.82  ? 167 TRP C CZ3 1 
ATOM   5900 C CH2 . TRP C 1 171 ? -46.983 26.192  41.851  1   28.65  ? 167 TRP C CH2 1 
ATOM   5901 N N   . TYR C 1 172 ? -50.884 18.932  39.206  1   22.77  ? 168 TYR C N   1 
ATOM   5902 C CA  . TYR C 1 172 ? -51.213 18.312  37.922  1   20.71  ? 168 TYR C CA  1 
ATOM   5903 C C   . TYR C 1 172 ? -51.957 17.004  38.173  1   21.77  ? 168 TYR C C   1 
ATOM   5904 O O   . TYR C 1 172 ? -52.229 16.234  37.247  1   24.29  ? 168 TYR C O   1 
ATOM   5905 C CB  . TYR C 1 172 ? -49.958 18.115  37.046  1   17.75  ? 168 TYR C CB  1 
ATOM   5906 C CG  . TYR C 1 172 ? -49.227 19.436  36.873  1   17.01  ? 168 TYR C CG  1 
ATOM   5907 C CD1 . TYR C 1 172 ? -49.602 20.334  35.887  1   16.56  ? 168 TYR C CD1 1 
ATOM   5908 C CD2 . TYR C 1 172 ? -48.277 19.856  37.797  1   16.83  ? 168 TYR C CD2 1 
ATOM   5909 C CE1 . TYR C 1 172 ? -49.042 21.597  35.802  1   17.48  ? 168 TYR C CE1 1 
ATOM   5910 C CE2 . TYR C 1 172 ? -47.672 21.097  37.699  1   16.94  ? 168 TYR C CE2 1 
ATOM   5911 C CZ  . TYR C 1 172 ? -48.051 21.974  36.696  1   19.34  ? 168 TYR C CZ  1 
ATOM   5912 O OH  . TYR C 1 172 ? -47.462 23.217  36.608  1   22.75  ? 168 TYR C OH  1 
ATOM   5913 N N   . ARG C 1 173 ? -52.272 16.757  39.443  1   22.4   ? 169 ARG C N   1 
ATOM   5914 C CA  . ARG C 1 173 ? -52.87  15.499  39.861  1   24.16  ? 169 ARG C CA  1 
ATOM   5915 C C   . ARG C 1 173 ? -54.38  15.529  39.614  1   24.24  ? 169 ARG C C   1 
ATOM   5916 O O   . ARG C 1 173 ? -55.065 16.479  40.008  1   23.27  ? 169 ARG C O   1 
ATOM   5917 C CB  . ARG C 1 173 ? -52.561 15.234  41.343  1   24.27  ? 169 ARG C CB  1 
ATOM   5918 C CG  . ARG C 1 173 ? -53.015 13.856  41.808  1   24.37  ? 169 ARG C CG  1 
ATOM   5919 C CD  . ARG C 1 173 ? -52.563 13.61   43.226  1   24.77  ? 169 ARG C CD  1 
ATOM   5920 N NE  . ARG C 1 173 ? -51.123 13.83   43.373  1   24     ? 169 ARG C NE  1 
ATOM   5921 C CZ  . ARG C 1 173 ? -50.494 14.12   44.515  1   23.66  ? 169 ARG C CZ  1 
ATOM   5922 N NH1 . ARG C 1 173 ? -51.149 14.273  45.657  1   20.1   ? 169 ARG C NH1 1 
ATOM   5923 N NH2 . ARG C 1 173 ? -49.183 14.269  44.495  1   22.53  ? 169 ARG C NH2 1 
ATOM   5924 N N   . ALA C 1 174 ? -54.877 14.448  38.99   1   24.24  ? 170 ALA C N   1 
ATOM   5925 C CA  . ALA C 1 174 ? -56.27  14.296  38.585  1   23.39  ? 170 ALA C CA  1 
ATOM   5926 C C   . ALA C 1 174 ? -57.147 14.099  39.815  1   24.41  ? 170 ALA C C   1 
ATOM   5927 O O   . ALA C 1 174 ? -56.71  13.526  40.812  1   26.39  ? 170 ALA C O   1 
ATOM   5928 C CB  . ALA C 1 174 ? -56.377 13.106  37.673  1   20.56  ? 170 ALA C CB  1 
ATOM   5929 N N   . PRO C 1 175 ? -58.419 14.524  39.791  1   24.06  ? 171 PRO C N   1 
ATOM   5930 C CA  . PRO C 1 175 ? -59.297 14.341  40.946  1   28.45  ? 171 PRO C CA  1 
ATOM   5931 C C   . PRO C 1 175 ? -59.463 12.889  41.398  1   29     ? 171 PRO C C   1 
ATOM   5932 O O   . PRO C 1 175 ? -59.566 12.636  42.598  1   28.71  ? 171 PRO C O   1 
ATOM   5933 C CB  . PRO C 1 175 ? -60.631 14.989  40.513  1   28.99  ? 171 PRO C CB  1 
ATOM   5934 C CG  . PRO C 1 175 ? -60.563 14.966  39.009  1   26.66  ? 171 PRO C CG  1 
ATOM   5935 C CD  . PRO C 1 175 ? -59.09  15.18   38.671  1   25.41  ? 171 PRO C CD  1 
ATOM   5936 N N   . GLU C 1 176 ? -59.438 11.94   40.45   1   27.85  ? 172 GLU C N   1 
ATOM   5937 C CA  . GLU C 1 176 ? -59.635 10.548  40.82   1   26.84  ? 172 GLU C CA  1 
ATOM   5938 C C   . GLU C 1 176 ? -58.502 10.08   41.728  1   26.96  ? 172 GLU C C   1 
ATOM   5939 O O   . GLU C 1 176 ? -58.743 9.269   42.608  1   28.63  ? 172 GLU C O   1 
ATOM   5940 C CB  . GLU C 1 176 ? -59.927 9.591   39.662  1   27.63  ? 172 GLU C CB  1 
ATOM   5941 C CG  . GLU C 1 176 ? -58.815 9.456   38.624  1   26     ? 172 GLU C CG  1 
ATOM   5942 C CD  . GLU C 1 176 ? -58.841 10.468  37.483  1   26.01  ? 172 GLU C CD  1 
ATOM   5943 O OE1 . GLU C 1 176 ? -58.262 10.15   36.411  1   23.12  ? 172 GLU C OE1 1 
ATOM   5944 O OE2 . GLU C 1 176 ? -59.422 11.574  37.672  1   25.08  ? 172 GLU C OE2 1 
ATOM   5945 N N   . ILE C 1 177 ? -57.284 10.613  41.554  1   26.43  ? 173 ILE C N   1 
ATOM   5946 C CA  . ILE C 1 177 ? -56.209 10.206  42.45   1   27.11  ? 173 ILE C CA  1 
ATOM   5947 C C   . ILE C 1 177 ? -56.403 10.855  43.819  1   28.24  ? 173 ILE C C   1 
ATOM   5948 O O   . ILE C 1 177 ? -56.203 10.216  44.847  1   30.21  ? 173 ILE C O   1 
ATOM   5949 C CB  . ILE C 1 177 ? -54.81  10.476  41.864  1   28.42  ? 173 ILE C CB  1 
ATOM   5950 C CG1 . ILE C 1 177 ? -54.594 9.773   40.539  1   29.47  ? 173 ILE C CG1 1 
ATOM   5951 C CG2 . ILE C 1 177 ? -53.71  10.053  42.832  1   27.57  ? 173 ILE C CG2 1 
ATOM   5952 C CD1 . ILE C 1 177 ? -53.416 10.345  39.764  1   34.15  ? 173 ILE C CD1 1 
ATOM   5953 N N   . LEU C 1 178 ? -56.809 12.127  43.821  1   31.03  ? 174 LEU C N   1 
ATOM   5954 C CA  . LEU C 1 178 ? -56.969 12.919  45.033  1   31.23  ? 174 LEU C CA  1 
ATOM   5955 C C   . LEU C 1 178 ? -58.033 12.305  45.944  1   33.84  ? 174 LEU C C   1 
ATOM   5956 O O   . LEU C 1 178 ? -57.829 12.247  47.148  1   37.54  ? 174 LEU C O   1 
ATOM   5957 C CB  . LEU C 1 178 ? -57.307 14.361  44.652  1   30.42  ? 174 LEU C CB  1 
ATOM   5958 C CG  . LEU C 1 178 ? -56.194 15.181  43.987  1   30.06  ? 174 LEU C CG  1 
ATOM   5959 C CD1 . LEU C 1 178 ? -56.775 16.414  43.289  1   28.88  ? 174 LEU C CD1 1 
ATOM   5960 C CD2 . LEU C 1 178 ? -55.139 15.586  45.018  1   30.67  ? 174 LEU C CD2 1 
ATOM   5961 N N   . LEU C 1 179 ? -59.14  11.831  45.355  1   33.11  ? 175 LEU C N   1 
ATOM   5962 C CA  . LEU C 1 179 ? -60.25  11.217  46.062  1   34.56  ? 175 LEU C CA  1 
ATOM   5963 C C   . LEU C 1 179 ? -59.987 9.728   46.322  1   39.35  ? 175 LEU C C   1 
ATOM   5964 O O   . LEU C 1 179 ? -60.918 8.976   46.634  1   38.85  ? 175 LEU C O   1 
ATOM   5965 C CB  . LEU C 1 179 ? -61.505 11.422  45.213  1   35.72  ? 175 LEU C CB  1 
ATOM   5966 C CG  . LEU C 1 179 ? -61.933 12.872  44.957  1   35.74  ? 175 LEU C CG  1 
ATOM   5967 C CD1 . LEU C 1 179 ? -63.13  12.988  44.045  1   35.29  ? 175 LEU C CD1 1 
ATOM   5968 C CD2 . LEU C 1 179 ? -62.255 13.582  46.248  1   38.35  ? 175 LEU C CD2 1 
ATOM   5969 N N   . GLY C 1 180 ? -58.717 9.308   46.183  1   39.58  ? 176 GLY C N   1 
ATOM   5970 C CA  . GLY C 1 180 ? -58.221 8.001   46.599  1   38.43  ? 176 GLY C CA  1 
ATOM   5971 C C   . GLY C 1 180 ? -58.946 6.836   45.925  1   39.31  ? 176 GLY C C   1 
ATOM   5972 O O   . GLY C 1 180 ? -59.295 5.866   46.594  1   42.36  ? 176 GLY C O   1 
ATOM   5973 N N   . CYS C 1 181 ? -59.184 6.952   44.609  1   36.68  ? 177 CYS C N   1 
ATOM   5974 C CA  . CYS C 1 181 ? -59.848 5.913   43.838  1   35.59  ? 177 CYS C CA  1 
ATOM   5975 C C   . CYS C 1 181 ? -58.902 4.736   43.707  1   34.83  ? 177 CYS C C   1 
ATOM   5976 O O   . CYS C 1 181 ? -57.695 4.921   43.796  1   36.34  ? 177 CYS C O   1 
ATOM   5977 C CB  . CYS C 1 181 ? -60.214 6.374   42.435  1   42.06  ? 177 CYS C CB  1 
ATOM   5978 S SG  . CYS C 1 181 ? -61.629 7.511   42.371  1   60.15  ? 177 CYS C SG  1 
ATOM   5979 N N   . LYS C 1 182 ? -59.465 3.546   43.501  1   34.71  ? 178 LYS C N   1 
ATOM   5980 C CA  . LYS C 1 182 ? -58.703 2.309   43.538  1   37.2   ? 178 LYS C CA  1 
ATOM   5981 C C   . LYS C 1 182 ? -57.888 2.15    42.254  1   34.28  ? 178 LYS C C   1 
ATOM   5982 O O   . LYS C 1 182 ? -56.756 1.672   42.29   1   34.61  ? 178 LYS C O   1 
ATOM   5983 C CB  . LYS C 1 182 ? -59.646 1.112   43.73   1   41.16  ? 178 LYS C CB  1 
ATOM   5984 C CG  . LYS C 1 182 ? -58.953 -0.219  44.038  1   48.7   ? 178 LYS C CG  1 
ATOM   5985 C CD  . LYS C 1 182 ? -59.861 -1.441  43.957  1   54.45  ? 178 LYS C CD  1 
ATOM   5986 C CE  . LYS C 1 182 ? -59.292 -2.731  44.487  1   52.04  ? 178 LYS C CE  1 
ATOM   5987 N NZ  . LYS C 1 182 ? -60.195 -3.855  44.194  1   44.23  ? 178 LYS C NZ  1 
ATOM   5988 N N   . TYR C 1 183 ? -58.502 2.519   41.125  1   32.29  ? 179 TYR C N   1 
ATOM   5989 C CA  . TYR C 1 183 ? -57.899 2.407   39.809  1   31.74  ? 179 TYR C CA  1 
ATOM   5990 C C   . TYR C 1 183 ? -57.852 3.774   39.135  1   31.19  ? 179 TYR C C   1 
ATOM   5991 O O   . TYR C 1 183 ? -58.771 4.589   39.283  1   29.56  ? 179 TYR C O   1 
ATOM   5992 C CB  . TYR C 1 183 ? -58.728 1.509   38.887  1   32.61  ? 179 TYR C CB  1 
ATOM   5993 C CG  . TYR C 1 183 ? -58.97  0.095   39.394  1   34.27  ? 179 TYR C CG  1 
ATOM   5994 C CD1 . TYR C 1 183 ? -57.92  -0.694  39.857  1   35.84  ? 179 TYR C CD1 1 
ATOM   5995 C CD2 . TYR C 1 183 ? -60.254 -0.436  39.423  1   32.71  ? 179 TYR C CD2 1 
ATOM   5996 C CE1 . TYR C 1 183 ? -58.132 -1.982  40.325  1   37.09  ? 179 TYR C CE1 1 
ATOM   5997 C CE2 . TYR C 1 183 ? -60.475 -1.718  39.883  1   33.79  ? 179 TYR C CE2 1 
ATOM   5998 C CZ  . TYR C 1 183 ? -59.42  -2.49   40.34   1   38.38  ? 179 TYR C CZ  1 
ATOM   5999 O OH  . TYR C 1 183 ? -59.672 -3.756  40.801  1   45.93  ? 179 TYR C OH  1 
ATOM   6000 N N   . TYR C 1 184 ? -56.758 3.999   38.392  1   28.66  ? 180 TYR C N   1 
ATOM   6001 C CA  . TYR C 1 184 ? -56.644 5.119   37.472  1   25.97  ? 180 TYR C CA  1 
ATOM   6002 C C   . TYR C 1 184 ? -55.972 4.638   36.19   1   25.91  ? 180 TYR C C   1 
ATOM   6003 O O   . TYR C 1 184 ? -55.282 3.618   36.162  1   26.17  ? 180 TYR C O   1 
ATOM   6004 C CB  . TYR C 1 184 ? -55.882 6.283   38.104  1   26.18  ? 180 TYR C CB  1 
ATOM   6005 C CG  . TYR C 1 184 ? -54.443 5.949   38.472  1   27.39  ? 180 TYR C CG  1 
ATOM   6006 C CD1 . TYR C 1 184 ? -53.426 5.972   37.52   1   25.39  ? 180 TYR C CD1 1 
ATOM   6007 C CD2 . TYR C 1 184 ? -54.101 5.621   39.789  1   28.86  ? 180 TYR C CD2 1 
ATOM   6008 C CE1 . TYR C 1 184 ? -52.124 5.656   37.873  1   26.85  ? 180 TYR C CE1 1 
ATOM   6009 C CE2 . TYR C 1 184 ? -52.792 5.329   40.156  1   25.7   ? 180 TYR C CE2 1 
ATOM   6010 C CZ  . TYR C 1 184 ? -51.804 5.331   39.189  1   28.11  ? 180 TYR C CZ  1 
ATOM   6011 O OH  . TYR C 1 184 ? -50.518 5.009   39.546  1   32.27  ? 180 TYR C OH  1 
ATOM   6012 N N   . SER C 1 185 ? -56.152 5.419   35.13   1   26.58  ? 181 SER C N   1 
ATOM   6013 C CA  . SER C 1 185 ? -55.812 4.982   33.785  1   28.01  ? 181 SER C CA  1 
ATOM   6014 C C   . SER C 1 185 ? -55.223 6.153   33.003  1   25.49  ? 181 SER C C   1 
ATOM   6015 O O   . SER C 1 185 ? -54.831 7.156   33.604  1   24.9   ? 181 SER C O   1 
ATOM   6016 C CB  . SER C 1 185 ? -57.041 4.406   33.087  1   28.56  ? 181 SER C CB  1 
ATOM   6017 O OG  . SER C 1 185 ? -56.678 3.676   31.92   1   30.61  ? 181 SER C OG  1 
ATOM   6018 N N   . THR C 1 186 ? -55.215 6.01    31.669  1   25.38  ? 182 THR C N   1 
ATOM   6019 C CA  . THR C 1 186 ? -54.659 6.972   30.726  1   26.98  ? 182 THR C CA  1 
ATOM   6020 C C   . THR C 1 186 ? -55.221 8.364   30.974  1   26.95  ? 182 THR C C   1 
ATOM   6021 O O   . THR C 1 186 ? -54.589 9.349   30.602  1   32.1   ? 182 THR C O   1 
ATOM   6022 C CB  . THR C 1 186 ? -54.883 6.545   29.275  1   25.54  ? 182 THR C CB  1 
ATOM   6023 O OG1 . THR C 1 186 ? -56.298 6.421   29.179  1   26.96  ? 182 THR C OG1 1 
ATOM   6024 C CG2 . THR C 1 186 ? -54.16  5.258   28.925  1   21.97  ? 182 THR C CG2 1 
ATOM   6025 N N   . ALA C 1 187 ? -56.378 8.443   31.634  1   25.96  ? 183 ALA C N   1 
ATOM   6026 C CA  . ALA C 1 187 ? -57.032 9.726   31.86   1   25.43  ? 183 ALA C CA  1 
ATOM   6027 C C   . ALA C 1 187 ? -56.206 10.644  32.769  1   24.16  ? 183 ALA C C   1 
ATOM   6028 O O   . ALA C 1 187 ? -56.317 11.859  32.651  1   25.53  ? 183 ALA C O   1 
ATOM   6029 C CB  . ALA C 1 187 ? -58.456 9.522   32.353  1   23.49  ? 183 ALA C CB  1 
ATOM   6030 N N   . VAL C 1 188 ? -55.364 10.087  33.652  1   23.4   ? 184 VAL C N   1 
ATOM   6031 C CA  . VAL C 1 188 ? -54.641 10.926  34.596  1   24.55  ? 184 VAL C CA  1 
ATOM   6032 C C   . VAL C 1 188 ? -53.655 11.79   33.815  1   26.28  ? 184 VAL C C   1 
ATOM   6033 O O   . VAL C 1 188 ? -53.411 12.931  34.193  1   30.85  ? 184 VAL C O   1 
ATOM   6034 C CB  . VAL C 1 188 ? -53.943 10.204  35.765  1   25.9   ? 184 VAL C CB  1 
ATOM   6035 C CG1 . VAL C 1 188 ? -54.873 9.196   36.428  1   25.48  ? 184 VAL C CG1 1 
ATOM   6036 C CG2 . VAL C 1 188 ? -52.613 9.57    35.358  1   23.57  ? 184 VAL C CG2 1 
ATOM   6037 N N   . ASP C 1 189 ? -53.137 11.252  32.706  1   22.72  ? 185 ASP C N   1 
ATOM   6038 C CA  . ASP C 1 189 ? -52.178 11.973  31.892  1   24.03  ? 185 ASP C CA  1 
ATOM   6039 C C   . ASP C 1 189 ? -52.866 13.071  31.09   1   25.34  ? 185 ASP C C   1 
ATOM   6040 O O   . ASP C 1 189 ? -52.237 14.097  30.83   1   29.22  ? 185 ASP C O   1 
ATOM   6041 C CB  . ASP C 1 189 ? -51.377 11.03   31.007  1   25.93  ? 185 ASP C CB  1 
ATOM   6042 C CG  . ASP C 1 189 ? -50.293 10.242  31.73   1   27.21  ? 185 ASP C CG  1 
ATOM   6043 O OD1 . ASP C 1 189 ? -49.841 10.686  32.813  1   27.72  ? 185 ASP C OD1 1 
ATOM   6044 O OD2 . ASP C 1 189 ? -49.939 9.172   31.223  1   28.63  ? 185 ASP C OD2 1 
ATOM   6045 N N   . ILE C 1 190 ? -54.134 12.854  30.688  1   21.8   ? 186 ILE C N   1 
ATOM   6046 C CA  . ILE C 1 190 ? -54.87  13.885  29.972  1   21.31  ? 186 ILE C CA  1 
ATOM   6047 C C   . ILE C 1 190 ? -55.106 15.069  30.913  1   20.68  ? 186 ILE C C   1 
ATOM   6048 O O   . ILE C 1 190 ? -54.953 16.231  30.503  1   21.78  ? 186 ILE C O   1 
ATOM   6049 C CB  . ILE C 1 190 ? -56.181 13.39   29.29   1   21.46  ? 186 ILE C CB  1 
ATOM   6050 C CG1 . ILE C 1 190 ? -55.911 12.515  28.047  1   19.95  ? 186 ILE C CG1 1 
ATOM   6051 C CG2 . ILE C 1 190 ? -57.064 14.575  28.879  1   17.98  ? 186 ILE C CG2 1 
ATOM   6052 C CD1 . ILE C 1 190 ? -55.309 13.3    26.894  1   19.37  ? 186 ILE C CD1 1 
ATOM   6053 N N   . TRP C 1 191 ? -55.49  14.766  32.16   1   18.54  ? 187 TRP C N   1 
ATOM   6054 C CA  . TRP C 1 191 ? -55.774 15.813  33.125  1   18.56  ? 187 TRP C CA  1 
ATOM   6055 C C   . TRP C 1 191 ? -54.565 16.742  33.234  1   19.3   ? 187 TRP C C   1 
ATOM   6056 O O   . TRP C 1 191 ? -54.676 17.96   33.098  1   20.88  ? 187 TRP C O   1 
ATOM   6057 C CB  . TRP C 1 191 ? -56.158 15.202  34.48   1   18.29  ? 187 TRP C CB  1 
ATOM   6058 C CG  . TRP C 1 191 ? -56.455 16.243  35.525  1   19.55  ? 187 TRP C CG  1 
ATOM   6059 C CD1 . TRP C 1 191 ? -55.544 16.885  36.317  1   19.28  ? 187 TRP C CD1 1 
ATOM   6060 C CD2 . TRP C 1 191 ? -57.751 16.802  35.849  1   19.79  ? 187 TRP C CD2 1 
ATOM   6061 N NE1 . TRP C 1 191 ? -56.19  17.783  37.121  1   20.47  ? 187 TRP C NE1 1 
ATOM   6062 C CE2 . TRP C 1 191 ? -57.536 17.759  36.86   1   18.93  ? 187 TRP C CE2 1 
ATOM   6063 C CE3 . TRP C 1 191 ? -59.058 16.579  35.392  1   20.41  ? 187 TRP C CE3 1 
ATOM   6064 C CZ2 . TRP C 1 191 ? -58.579 18.486  37.422  1   19.35  ? 187 TRP C CZ2 1 
ATOM   6065 C CZ3 . TRP C 1 191 ? -60.092 17.292  35.951  1   20.25  ? 187 TRP C CZ3 1 
ATOM   6066 C CH2 . TRP C 1 191 ? -59.846 18.245  36.943  1   21.01  ? 187 TRP C CH2 1 
ATOM   6067 N N   . SER C 1 192 ? -53.397 16.147  33.449  1   19.67  ? 188 SER C N   1 
ATOM   6068 C CA  . SER C 1 192 ? -52.167 16.903  33.569  1   20.6   ? 188 SER C CA  1 
ATOM   6069 C C   . SER C 1 192 ? -52.003 17.842  32.376  1   20.53  ? 188 SER C C   1 
ATOM   6070 O O   . SER C 1 192 ? -51.757 19.031  32.551  1   21.45  ? 188 SER C O   1 
ATOM   6071 C CB  . SER C 1 192 ? -50.973 15.968  33.735  1   23.15  ? 188 SER C CB  1 
ATOM   6072 O OG  . SER C 1 192 ? -51.109 15.064  34.833  1   22.89  ? 188 SER C OG  1 
ATOM   6073 N N   . LEU C 1 193 ? -52.155 17.308  31.161  1   20.99  ? 189 LEU C N   1 
ATOM   6074 C CA  . LEU C 1 193 ? -52.009 18.091  29.942  1   20.44  ? 189 LEU C CA  1 
ATOM   6075 C C   . LEU C 1 193 ? -53.068 19.183  29.865  1   21.62  ? 189 LEU C C   1 
ATOM   6076 O O   . LEU C 1 193 ? -52.814 20.249  29.313  1   22.32  ? 189 LEU C O   1 
ATOM   6077 C CB  . LEU C 1 193 ? -52.111 17.214  28.701  1   19.78  ? 189 LEU C CB  1 
ATOM   6078 C CG  . LEU C 1 193 ? -50.857 16.445  28.285  1   20.81  ? 189 LEU C CG  1 
ATOM   6079 C CD1 . LEU C 1 193 ? -51.032 15.911  26.893  1   19.53  ? 189 LEU C CD1 1 
ATOM   6080 C CD2 . LEU C 1 193 ? -49.632 17.321  28.34   1   20.34  ? 189 LEU C CD2 1 
ATOM   6081 N N   . GLY C 1 194 ? -54.272 18.903  30.37   1   20.91  ? 190 GLY C N   1 
ATOM   6082 C CA  . GLY C 1 194 ? -55.272 19.951  30.467  1   20.46  ? 190 GLY C CA  1 
ATOM   6083 C C   . GLY C 1 194 ? -54.739 21.14   31.26   1   21.41  ? 190 GLY C C   1 
ATOM   6084 O O   . GLY C 1 194 ? -54.769 22.276  30.779  1   22.44  ? 190 GLY C O   1 
ATOM   6085 N N   . CYS C 1 195 ? -54.232 20.839  32.46   1   20.67  ? 191 CYS C N   1 
ATOM   6086 C CA  . CYS C 1 195 ? -53.585 21.807  33.33   1   23.86  ? 191 CYS C CA  1 
ATOM   6087 C C   . CYS C 1 195 ? -52.46  22.552  32.592  1   25.58  ? 191 CYS C C   1 
ATOM   6088 O O   . CYS C 1 195 ? -52.303 23.762  32.732  1   26.1   ? 191 CYS C O   1 
ATOM   6089 C CB  . CYS C 1 195 ? -53.1   21.116  34.604  1   24.01  ? 191 CYS C CB  1 
ATOM   6090 S SG  . CYS C 1 195 ? -54.432 20.366  35.587  1   25.7   ? 191 CYS C SG  1 
ATOM   6091 N N   . ILE C 1 196 ? -51.674 21.833  31.79   1   27.04  ? 192 ILE C N   1 
ATOM   6092 C CA  . ILE C 1 196 ? -50.553 22.426  31.078  1   28.49  ? 192 ILE C CA  1 
ATOM   6093 C C   . ILE C 1 196 ? -51.073 23.331  29.951  1   29.2   ? 192 ILE C C   1 
ATOM   6094 O O   . ILE C 1 196 ? -50.603 24.468  29.812  1   28.12  ? 192 ILE C O   1 
ATOM   6095 C CB  . ILE C 1 196 ? -49.582 21.314  30.621  1   30.1   ? 192 ILE C CB  1 
ATOM   6096 C CG1 . ILE C 1 196 ? -48.798 20.78   31.83   1   30.11  ? 192 ILE C CG1 1 
ATOM   6097 C CG2 . ILE C 1 196 ? -48.636 21.782  29.51   1   26.23  ? 192 ILE C CG2 1 
ATOM   6098 C CD1 . ILE C 1 196 ? -48.542 19.289  31.778  1   30.93  ? 192 ILE C CD1 1 
ATOM   6099 N N   . PHE C 1 197 ? -52.059 22.842  29.169  1   25.02  ? 193 PHE C N   1 
ATOM   6100 C CA  . PHE C 1 197 ? -52.736 23.672  28.187  1   22.35  ? 193 PHE C CA  1 
ATOM   6101 C C   . PHE C 1 197 ? -53.076 25.019  28.822  1   22.39  ? 193 PHE C C   1 
ATOM   6102 O O   . PHE C 1 197 ? -52.639 26.044  28.331  1   25.14  ? 193 PHE C O   1 
ATOM   6103 C CB  . PHE C 1 197 ? -53.965 22.94   27.649  1   21.68  ? 193 PHE C CB  1 
ATOM   6104 C CG  . PHE C 1 197 ? -54.715 23.609  26.51   1   21.05  ? 193 PHE C CG  1 
ATOM   6105 C CD1 . PHE C 1 197 ? -54.161 24.658  25.789  1   21.25  ? 193 PHE C CD1 1 
ATOM   6106 C CD2 . PHE C 1 197 ? -55.977 23.167  26.142  1   23.03  ? 193 PHE C CD2 1 
ATOM   6107 C CE1 . PHE C 1 197 ? -54.858 25.247  24.742  1   21.81  ? 193 PHE C CE1 1 
ATOM   6108 C CE2 . PHE C 1 197 ? -56.668 23.754  25.081  1   22.09  ? 193 PHE C CE2 1 
ATOM   6109 C CZ  . PHE C 1 197 ? -56.109 24.793  24.383  1   21.78  ? 193 PHE C CZ  1 
ATOM   6110 N N   . ALA C 1 198 ? -53.811 25.018  29.94   1   21.42  ? 194 ALA C N   1 
ATOM   6111 C CA  . ALA C 1 198 ? -54.281 26.254  30.554  1   22.98  ? 194 ALA C CA  1 
ATOM   6112 C C   . ALA C 1 198 ? -53.108 27.111  31.005  1   24.92  ? 194 ALA C C   1 
ATOM   6113 O O   . ALA C 1 198 ? -53.207 28.34   30.988  1   26.37  ? 194 ALA C O   1 
ATOM   6114 C CB  . ALA C 1 198 ? -55.215 25.996  31.728  1   21.04  ? 194 ALA C CB  1 
ATOM   6115 N N   . GLU C 1 199 ? -52.045 26.445  31.473  1   23.7   ? 195 GLU C N   1 
ATOM   6116 C CA  . GLU C 1 199 ? -50.873 27.118  32.011  1   25.53  ? 195 GLU C CA  1 
ATOM   6117 C C   . GLU C 1 199 ? -50.083 27.758  30.861  1   26.58  ? 195 GLU C C   1 
ATOM   6118 O O   . GLU C 1 199 ? -49.508 28.833  31.031  1   26.02  ? 195 GLU C O   1 
ATOM   6119 C CB  . GLU C 1 199 ? -50.089 26.156  32.914  1   26.34  ? 195 GLU C CB  1 
ATOM   6120 C CG  . GLU C 1 199 ? -48.888 26.775  33.626  1   27.27  ? 195 GLU C CG  1 
ATOM   6121 C CD  . GLU C 1 199 ? -48.159 25.876  34.611  1   28.76  ? 195 GLU C CD  1 
ATOM   6122 O OE1 . GLU C 1 199 ? -48.698 24.79   34.94   1   26.61  ? 195 GLU C OE1 1 
ATOM   6123 O OE2 . GLU C 1 199 ? -47.039 26.264  35.05   1   31.67  ? 195 GLU C OE2 1 
ATOM   6124 N N   . MET C 1 200 ? -50.066 27.128  29.678  1   25.25  ? 196 MET C N   1 
ATOM   6125 C CA  . MET C 1 200 ? -49.402 27.745  28.539  1   23.96  ? 196 MET C CA  1 
ATOM   6126 C C   . MET C 1 200 ? -50.077 29.063  28.147  1   27.29  ? 196 MET C C   1 
ATOM   6127 O O   . MET C 1 200 ? -49.394 30.011  27.748  1   28.19  ? 196 MET C O   1 
ATOM   6128 C CB  . MET C 1 200 ? -49.345 26.792  27.346  1   23.17  ? 196 MET C CB  1 
ATOM   6129 C CG  . MET C 1 200 ? -48.178 25.843  27.429  1   24.09  ? 196 MET C CG  1 
ATOM   6130 S SD  . MET C 1 200 ? -48.004 24.919  25.898  1   27.82  ? 196 MET C SD  1 
ATOM   6131 C CE  . MET C 1 200 ? -49.387 23.774  25.956  1   24.89  ? 196 MET C CE  1 
ATOM   6132 N N   . VAL C 1 201 ? -51.412 29.13   28.309  1   27.43  ? 197 VAL C N   1 
ATOM   6133 C CA  . VAL C 1 201 ? -52.218 30.27   27.909  1   26.46  ? 197 VAL C CA  1 
ATOM   6134 C C   . VAL C 1 201 ? -52.118 31.418  28.919  1   31.66  ? 197 VAL C C   1 
ATOM   6135 O O   . VAL C 1 201 ? -51.975 32.573  28.503  1   38.69  ? 197 VAL C O   1 
ATOM   6136 C CB  . VAL C 1 201 ? -53.684 29.867  27.711  1   24.99  ? 197 VAL C CB  1 
ATOM   6137 C CG1 . VAL C 1 201 ? -54.572 31.105  27.695  1   23.02  ? 197 VAL C CG1 1 
ATOM   6138 C CG2 . VAL C 1 201 ? -53.888 28.974  26.487  1   20.78  ? 197 VAL C CG2 1 
ATOM   6139 N N   . THR C 1 202 ? -52.22  31.123  30.232  1   30.7   ? 198 THR C N   1 
ATOM   6140 C CA  . THR C 1 202 ? -52.134 32.158  31.262  1   28.58  ? 198 THR C CA  1 
ATOM   6141 C C   . THR C 1 202 ? -50.706 32.324  31.781  1   27.46  ? 198 THR C C   1 
ATOM   6142 O O   . THR C 1 202 ? -50.421 33.286  32.476  1   25.43  ? 198 THR C O   1 
ATOM   6143 C CB  . THR C 1 202 ? -53.087 31.923  32.436  1   28.5   ? 198 THR C CB  1 
ATOM   6144 O OG1 . THR C 1 202 ? -52.657 30.719  33.051  1   34.18  ? 198 THR C OG1 1 
ATOM   6145 C CG2 . THR C 1 202 ? -54.549 31.793  32.06   1   25.01  ? 198 THR C CG2 1 
ATOM   6146 N N   . ARG C 1 203 ? -49.82  31.359  31.501  1   31.97  ? 199 ARG C N   1 
ATOM   6147 C CA  . ARG C 1 203 ? -48.478 31.327  32.085  1   35.84  ? 199 ARG C CA  1 
ATOM   6148 C C   . ARG C 1 203 ? -48.502 31.236  33.617  1   35.86  ? 199 ARG C C   1 
ATOM   6149 O O   . ARG C 1 203 ? -47.472 31.41   34.257  1   35.99  ? 199 ARG C O   1 
ATOM   6150 C CB  . ARG C 1 203 ? -47.606 32.484  31.583  1   37.63  ? 199 ARG C CB  1 
ATOM   6151 C CG  . ARG C 1 203 ? -46.738 32.207  30.362  1   35.61  ? 199 ARG C CG  1 
ATOM   6152 C CD  . ARG C 1 203 ? -46.345 33.516  29.713  1   43.02  ? 199 ARG C CD  1 
ATOM   6153 N NE  . ARG C 1 203 ? -47.566 34.082  29.128  1   50.86  ? 199 ARG C NE  1 
ATOM   6154 C CZ  . ARG C 1 203 ? -48.073 35.294  29.319  1   48.31  ? 199 ARG C CZ  1 
ATOM   6155 N NH1 . ARG C 1 203 ? -47.379 36.223  29.956  1   43.45  ? 199 ARG C NH1 1 
ATOM   6156 N NH2 . ARG C 1 203 ? -49.286 35.542  28.854  1   52.39  ? 199 ARG C NH2 1 
ATOM   6157 N N   . ARG C 1 204 ? -49.675 30.913  34.15   1   35.59  ? 200 ARG C N   1 
ATOM   6158 C CA  . ARG C 1 204 ? -49.821 30.695  35.603  1   30.34  ? 200 ARG C CA  1 
ATOM   6159 C C   . ARG C 1 204 ? -50.449 29.311  35.772  1   29.84  ? 200 ARG C C   1 
ATOM   6160 O O   . ARG C 1 204 ? -51.295 28.955  34.935  1   30.13  ? 200 ARG C O   1 
ATOM   6161 C CB  . ARG C 1 204 ? -50.712 31.774  36.219  1   29.84  ? 200 ARG C CB  1 
ATOM   6162 C CG  . ARG C 1 204 ? -50.257 33.208  36.008  1   32.1   ? 200 ARG C CG  1 
ATOM   6163 C CD  . ARG C 1 204 ? -51.341 34.168  36.45   1   34.92  ? 200 ARG C CD  1 
ATOM   6164 N NE  . ARG C 1 204 ? -51.819 34.992  35.337  1   37.01  ? 200 ARG C NE  1 
ATOM   6165 C CZ  . ARG C 1 204 ? -51.599 36.293  35.234  1   38.63  ? 200 ARG C CZ  1 
ATOM   6166 N NH1 . ARG C 1 204 ? -51.41  37.016  36.321  1   39.65  ? 200 ARG C NH1 1 
ATOM   6167 N NH2 . ARG C 1 204 ? -51.565 36.865  34.046  1   36.48  ? 200 ARG C NH2 1 
ATOM   6168 N N   . ALA C 1 205 ? -50.038 28.563  36.794  1   27.03  ? 201 ALA C N   1 
ATOM   6169 C CA  . ALA C 1 205 ? -50.606 27.25   37.08   1   22.32  ? 201 ALA C CA  1 
ATOM   6170 C C   . ALA C 1 205 ? -52.107 27.402  37.28   1   21.09  ? 201 ALA C C   1 
ATOM   6171 O O   . ALA C 1 205 ? -52.558 28.411  37.795  1   21.99  ? 201 ALA C O   1 
ATOM   6172 C CB  . ALA C 1 205 ? -49.978 26.67   38.317  1   21.38  ? 201 ALA C CB  1 
ATOM   6173 N N   . LEU C 1 206 ? -52.869 26.39   36.881  1   21.76  ? 202 LEU C N   1 
ATOM   6174 C CA  . LEU C 1 206 ? -54.314 26.501  36.86   1   21.5   ? 202 LEU C CA  1 
ATOM   6175 C C   . LEU C 1 206 ? -54.853 26.189  38.247  1   22.65  ? 202 LEU C C   1 
ATOM   6176 O O   . LEU C 1 206 ? -55.799 26.819  38.676  1   26.56  ? 202 LEU C O   1 
ATOM   6177 C CB  . LEU C 1 206 ? -54.872 25.557  35.795  1   21.76  ? 202 LEU C CB  1 
ATOM   6178 C CG  . LEU C 1 206 ? -56.396 25.379  35.753  1   22.34  ? 202 LEU C CG  1 
ATOM   6179 C CD1 . LEU C 1 206 ? -57.141 26.659  35.326  1   20.84  ? 202 LEU C CD1 1 
ATOM   6180 C CD2 . LEU C 1 206 ? -56.783 24.166  34.894  1   18.98  ? 202 LEU C CD2 1 
ATOM   6181 N N   . PHE C 1 207 ? -54.253 25.218  38.937  1   24.08  ? 203 PHE C N   1 
ATOM   6182 C CA  . PHE C 1 207 ? -54.707 24.825  40.26   1   24.4   ? 203 PHE C CA  1 
ATOM   6183 C C   . PHE C 1 207 ? -53.505 24.674  41.196  1   27.16  ? 203 PHE C C   1 
ATOM   6184 O O   . PHE C 1 207 ? -53.071 23.553  41.463  1   30.54  ? 203 PHE C O   1 
ATOM   6185 C CB  . PHE C 1 207 ? -55.379 23.45   40.145  1   23.49  ? 203 PHE C CB  1 
ATOM   6186 C CG  . PHE C 1 207 ? -56.583 23.337  39.226  1   21.89  ? 203 PHE C CG  1 
ATOM   6187 C CD1 . PHE C 1 207 ? -57.66  24.207  39.335  1   20.89  ? 203 PHE C CD1 1 
ATOM   6188 C CD2 . PHE C 1 207 ? -56.645 22.324  38.285  1   21.77  ? 203 PHE C CD2 1 
ATOM   6189 C CE1 . PHE C 1 207 ? -58.738 24.109  38.478  1   21.5   ? 203 PHE C CE1 1 
ATOM   6190 C CE2 . PHE C 1 207 ? -57.743 22.206  37.444  1   22.67  ? 203 PHE C CE2 1 
ATOM   6191 C CZ  . PHE C 1 207 ? -58.79  23.099  37.544  1   22.81  ? 203 PHE C CZ  1 
ATOM   6192 N N   . PRO C 1 208 ? -52.949 25.782  41.754  1   28.65  ? 204 PRO C N   1 
ATOM   6193 C CA  . PRO C 1 208 ? -51.769 25.7    42.599  1   26.49  ? 204 PRO C CA  1 
ATOM   6194 C C   . PRO C 1 208 ? -52.102 25.452  44.055  1   26.78  ? 204 PRO C C   1 
ATOM   6195 O O   . PRO C 1 208 ? -52.102 26.396  44.853  1   31.19  ? 204 PRO C O   1 
ATOM   6196 C CB  . PRO C 1 208 ? -51.137 27.07   42.373  1   25.81  ? 204 PRO C CB  1 
ATOM   6197 C CG  . PRO C 1 208 ? -52.291 28.02   42.21   1   24.9   ? 204 PRO C CG  1 
ATOM   6198 C CD  . PRO C 1 208 ? -53.413 27.184  41.653  1   26.36  ? 204 PRO C CD  1 
ATOM   6199 N N   . GLY C 1 209 ? -52.328 24.197  44.417  1   24.09  ? 205 GLY C N   1 
ATOM   6200 C CA  . GLY C 1 209 ? -52.754 23.879  45.786  1   24.42  ? 205 GLY C CA  1 
ATOM   6201 C C   . GLY C 1 209 ? -51.612 23.725  46.76   1   25.8   ? 205 GLY C C   1 
ATOM   6202 O O   . GLY C 1 209 ? -50.529 23.289  46.346  1   23.43  ? 205 GLY C O   1 
ATOM   6203 N N   . ASP C 1 210 ? -51.864 24.057  48.024  1   30.32  ? 206 ASP C N   1 
ATOM   6204 C CA  . ASP C 1 210 ? -50.831 23.931  49.083  1   32.7   ? 206 ASP C CA  1 
ATOM   6205 C C   . ASP C 1 210 ? -51.06  22.611  49.82   1   34.52  ? 206 ASP C C   1 
ATOM   6206 O O   . ASP C 1 210 ? -50.21  22.244  50.642  1   40.63  ? 206 ASP C O   1 
ATOM   6207 C CB  . ASP C 1 210 ? -50.832 25.153  49.986  1   33.01  ? 206 ASP C CB  1 
ATOM   6208 C CG  . ASP C 1 210 ? -50.305 26.452  49.392  1   38.49  ? 206 ASP C CG  1 
ATOM   6209 O OD1 . ASP C 1 210 ? -49.651 26.393  48.332  1   38.76  ? 206 ASP C OD1 1 
ATOM   6210 O OD2 . ASP C 1 210 ? -50.528 27.51   50.012  1   38.77  ? 206 ASP C OD2 1 
ATOM   6211 N N   . SER C 1 211 ? -52.158 21.927  49.51   1   32.9   ? 207 SER C N   1 
ATOM   6212 C CA  . SER C 1 211 ? -52.488 20.629  50.143  1   33     ? 207 SER C CA  1 
ATOM   6213 C C   . SER C 1 211 ? -53.407 19.84   49.208  1   36.39  ? 207 SER C C   1 
ATOM   6214 O O   . SER C 1 211 ? -53.768 20.376  48.15   1   39.49  ? 207 SER C O   1 
ATOM   6215 C CB  . SER C 1 211 ? -53.146 20.839  51.46   1   33.56  ? 207 SER C CB  1 
ATOM   6216 O OG  . SER C 1 211 ? -54.553 20.928  51.308  1   33.54  ? 207 SER C OG  1 
ATOM   6217 N N   . GLU C 1 212 ? -53.773 18.623  49.597  1   34.33  ? 208 GLU C N   1 
ATOM   6218 C CA  . GLU C 1 212 ? -54.694 17.795  48.785  1   33.59  ? 208 GLU C CA  1 
ATOM   6219 C C   . GLU C 1 212 ? -56.118 18.334  48.934  1   32.24  ? 208 GLU C C   1 
ATOM   6220 O O   . GLU C 1 212 ? -56.839 18.387  47.929  1   30.37  ? 208 GLU C O   1 
ATOM   6221 C CB  . GLU C 1 212 ? -54.597 16.357  49.277  1   37.03  ? 208 GLU C CB  1 
ATOM   6222 C CG  . GLU C 1 212 ? -53.464 15.565  48.637  1   43.12  ? 208 GLU C CG  1 
ATOM   6223 C CD  . GLU C 1 212 ? -53.31  14.205  49.287  1   47.24  ? 208 GLU C CD  1 
ATOM   6224 O OE1 . GLU C 1 212 ? -54.141 13.32   49.007  1   49.35  ? 208 GLU C OE1 1 
ATOM   6225 O OE2 . GLU C 1 212 ? -52.363 14.035  50.078  1   46.13  ? 208 GLU C OE2 1 
ATOM   6226 N N   . ILE C 1 213 ? -56.5   18.707  50.153  1   32.9   ? 209 ILE C N   1 
ATOM   6227 C CA  . ILE C 1 213 ? -57.842 19.318  50.379  1   31.17  ? 209 ILE C CA  1 
ATOM   6228 C C   . ILE C 1 213 ? -57.852 20.682  49.679  1   29.4   ? 209 ILE C C   1 
ATOM   6229 O O   . ILE C 1 213 ? -58.884 21.024  49.101  1   28.14  ? 209 ILE C O   1 
ATOM   6230 C CB  . ILE C 1 213 ? -58.181 19.396  51.882  1   31.28  ? 209 ILE C CB  1 
ATOM   6231 C CG1 . ILE C 1 213 ? -59.69  19.395  52.112  1   36.51  ? 209 ILE C CG1 1 
ATOM   6232 C CG2 . ILE C 1 213 ? -57.514 20.584  52.573  1   31.07  ? 209 ILE C CG2 1 
ATOM   6233 C CD1 . ILE C 1 213 ? -60.437 18.341  51.319  1   35.89  ? 209 ILE C CD1 1 
ATOM   6234 N N   . ASP C 1 214 ? -56.719 21.382  49.683  1   27.85  ? 210 ASP C N   1 
ATOM   6235 C CA  . ASP C 1 214 ? -56.636 22.669  48.949  1   28.4   ? 210 ASP C CA  1 
ATOM   6236 C C   . ASP C 1 214 ? -56.735 22.369  47.453  1   27.68  ? 210 ASP C C   1 
ATOM   6237 O O   . ASP C 1 214 ? -57.423 23.119  46.75   1   26.78  ? 210 ASP C O   1 
ATOM   6238 C CB  . ASP C 1 214 ? -55.399 23.465  49.329  1   29.03  ? 210 ASP C CB  1 
ATOM   6239 C CG  . ASP C 1 214 ? -55.389 24.91   48.861  1   31.54  ? 210 ASP C CG  1 
ATOM   6240 O OD1 . ASP C 1 214 ? -56.25  25.679  49.326  1   30.74  ? 210 ASP C OD1 1 
ATOM   6241 O OD2 . ASP C 1 214 ? -54.523 25.247  48.035  1   34.01  ? 210 ASP C OD2 1 
ATOM   6242 N N   . GLN C 1 215 ? -56.08  21.3    47.001  1   26.12  ? 211 GLN C N   1 
ATOM   6243 C CA  . GLN C 1 215 ? -56.112 21.024  45.573  1   26.2   ? 211 GLN C CA  1 
ATOM   6244 C C   . GLN C 1 215 ? -57.547 20.794  45.094  1   25.81  ? 211 GLN C C   1 
ATOM   6245 O O   . GLN C 1 215 ? -57.961 21.34   44.074  1   24.44  ? 211 GLN C O   1 
ATOM   6246 C CB  . GLN C 1 215 ? -55.241 19.81   45.261  1   27.35  ? 211 GLN C CB  1 
ATOM   6247 C CG  . GLN C 1 215 ? -54.923 19.628  43.78   1   31.04  ? 211 GLN C CG  1 
ATOM   6248 C CD  . GLN C 1 215 ? -54.025 20.704  43.206  1   34.88  ? 211 GLN C CD  1 
ATOM   6249 O OE1 . GLN C 1 215 ? -53.25  21.351  43.926  1   35.72  ? 211 GLN C OE1 1 
ATOM   6250 N NE2 . GLN C 1 215 ? -54.112 20.885  41.895  1   31.54  ? 211 GLN C NE2 1 
ATOM   6251 N N   . LEU C 1 216 ? -58.307 19.974  45.83   1   27.13  ? 212 LEU C N   1 
ATOM   6252 C CA  . LEU C 1 216 ? -59.697 19.685  45.486  1   26.79  ? 212 LEU C CA  1 
ATOM   6253 C C   . LEU C 1 216 ? -60.546 20.959  45.474  1   25.67  ? 212 LEU C C   1 
ATOM   6254 O O   . LEU C 1 216 ? -61.326 21.21   44.547  1   23.88  ? 212 LEU C O   1 
ATOM   6255 C CB  . LEU C 1 216 ? -60.241 18.668  46.485  1   26.65  ? 212 LEU C CB  1 
ATOM   6256 C CG  . LEU C 1 216 ? -59.911 17.214  46.144  1   28.39  ? 212 LEU C CG  1 
ATOM   6257 C CD1 . LEU C 1 216 ? -60.374 16.264  47.234  1   29.38  ? 212 LEU C CD1 1 
ATOM   6258 C CD2 . LEU C 1 216 ? -60.513 16.839  44.789  1   26.31  ? 212 LEU C CD2 1 
ATOM   6259 N N   . PHE C 1 217 ? -60.379 21.76   46.528  1   23.64  ? 213 PHE C N   1 
ATOM   6260 C CA  . PHE C 1 217 ? -61.099 23.007  46.656  1   23.72  ? 213 PHE C CA  1 
ATOM   6261 C C   . PHE C 1 217 ? -60.794 23.919  45.465  1   24.72  ? 213 PHE C C   1 
ATOM   6262 O O   . PHE C 1 217 ? -61.677 24.649  45.006  1   25.52  ? 213 PHE C O   1 
ATOM   6263 C CB  . PHE C 1 217 ? -60.813 23.667  48.011  1   23.81  ? 213 PHE C CB  1 
ATOM   6264 C CG  . PHE C 1 217 ? -61.36  22.986  49.258  1   23.6   ? 213 PHE C CG  1 
ATOM   6265 C CD1 . PHE C 1 217 ? -62.149 21.841  49.18   1   24.08  ? 213 PHE C CD1 1 
ATOM   6266 C CD2 . PHE C 1 217 ? -61.052 23.488  50.516  1   23.03  ? 213 PHE C CD2 1 
ATOM   6267 C CE1 . PHE C 1 217 ? -62.619 21.229  50.33   1   24.45  ? 213 PHE C CE1 1 
ATOM   6268 C CE2 . PHE C 1 217 ? -61.528 22.873  51.658  1   24.26  ? 213 PHE C CE2 1 
ATOM   6269 C CZ  . PHE C 1 217 ? -62.327 21.76   51.565  1   24.52  ? 213 PHE C CZ  1 
ATOM   6270 N N   . ARG C 1 218 ? -59.546 23.907  44.969  1   24.15  ? 214 ARG C N   1 
ATOM   6271 C CA  . ARG C 1 218 ? -59.19  24.779  43.857  1   23.58  ? 214 ARG C CA  1 
ATOM   6272 C C   . ARG C 1 218 ? -59.849 24.293  42.568  1   22.41  ? 214 ARG C C   1 
ATOM   6273 O O   . ARG C 1 218 ? -60.326 25.075  41.751  1   23.14  ? 214 ARG C O   1 
ATOM   6274 C CB  . ARG C 1 218 ? -57.672 24.896  43.712  1   24.44  ? 214 ARG C CB  1 
ATOM   6275 C CG  . ARG C 1 218 ? -57.106 25.889  44.714  1   24.72  ? 214 ARG C CG  1 
ATOM   6276 C CD  . ARG C 1 218 ? -55.592 25.908  44.611  1   25.51  ? 214 ARG C CD  1 
ATOM   6277 N NE  . ARG C 1 218 ? -55.086 26.642  45.774  1   27.44  ? 214 ARG C NE  1 
ATOM   6278 C CZ  . ARG C 1 218 ? -54.777 27.927  45.74   1   27.94  ? 214 ARG C CZ  1 
ATOM   6279 N NH1 . ARG C 1 218 ? -55.006 28.636  44.639  1   26.54  ? 214 ARG C NH1 1 
ATOM   6280 N NH2 . ARG C 1 218 ? -54.248 28.479  46.817  1   27.67  ? 214 ARG C NH2 1 
ATOM   6281 N N   . ILE C 1 219 ? -59.86  22.979  42.39   1   21.42  ? 215 ILE C N   1 
ATOM   6282 C CA  . ILE C 1 219 ? -60.511 22.393  41.24   1   23.09  ? 215 ILE C CA  1 
ATOM   6283 C C   . ILE C 1 219 ? -62.015 22.703  41.284  1   25.54  ? 215 ILE C C   1 
ATOM   6284 O O   . ILE C 1 219 ? -62.567 23.235  40.321  1   28.5   ? 215 ILE C O   1 
ATOM   6285 C CB  . ILE C 1 219 ? -60.158 20.894  41.186  1   20.22  ? 215 ILE C CB  1 
ATOM   6286 C CG1 . ILE C 1 219 ? -58.632 20.726  41.015  1   17.57  ? 215 ILE C CG1 1 
ATOM   6287 C CG2 . ILE C 1 219 ? -60.951 20.211  40.069  1   18.72  ? 215 ILE C CG2 1 
ATOM   6288 C CD1 . ILE C 1 219 ? -58.112 19.323  41.276  1   17.76  ? 215 ILE C CD1 1 
ATOM   6289 N N   . PHE C 1 220 ? -62.66  22.394  42.419  1   26.3   ? 216 PHE C N   1 
ATOM   6290 C CA  . PHE C 1 220 ? -64.103 22.499  42.605  1   27.57  ? 216 PHE C CA  1 
ATOM   6291 C C   . PHE C 1 220 ? -64.605 23.913  42.319  1   29.29  ? 216 PHE C C   1 
ATOM   6292 O O   . PHE C 1 220 ? -65.591 24.069  41.604  1   29.54  ? 216 PHE C O   1 
ATOM   6293 C CB  . PHE C 1 220 ? -64.429 22.05   44.03   1   26.51  ? 216 PHE C CB  1 
ATOM   6294 C CG  . PHE C 1 220 ? -64.294 20.548  44.239  1   28.54  ? 216 PHE C CG  1 
ATOM   6295 C CD1 . PHE C 1 220 ? -63.863 19.7    43.216  1   26.59  ? 216 PHE C CD1 1 
ATOM   6296 C CD2 . PHE C 1 220 ? -64.632 19.983  45.464  1   29.32  ? 216 PHE C CD2 1 
ATOM   6297 C CE1 . PHE C 1 220 ? -63.779 18.334  43.419  1   26.23  ? 216 PHE C CE1 1 
ATOM   6298 C CE2 . PHE C 1 220 ? -64.537 18.617  45.657  1   29.15  ? 216 PHE C CE2 1 
ATOM   6299 C CZ  . PHE C 1 220 ? -64.102 17.796  44.641  1   28.06  ? 216 PHE C CZ  1 
ATOM   6300 N N   . ARG C 1 221 ? -63.92  24.912  42.879  1   30.3   ? 217 ARG C N   1 
ATOM   6301 C CA  . ARG C 1 221 ? -64.324 26.325  42.674  1   30.09  ? 217 ARG C CA  1 
ATOM   6302 C C   . ARG C 1 221 ? -64.321 26.658  41.18   1   31.41  ? 217 ARG C C   1 
ATOM   6303 O O   . ARG C 1 221 ? -65.242 27.376  40.736  1   30.44  ? 217 ARG C O   1 
ATOM   6304 C CB  . ARG C 1 221 ? -63.335 27.268  43.363  1   29.1   ? 217 ARG C CB  1 
ATOM   6305 C CG  . ARG C 1 221 ? -63.529 27.424  44.863  1   33.82  ? 217 ARG C CG  1 
ATOM   6306 C CD  . ARG C 1 221 ? -62.232 27.803  45.556  1   34.49  ? 217 ARG C CD  1 
ATOM   6307 N NE  . ARG C 1 221 ? -61.996 26.993  46.756  1   32.4   ? 217 ARG C NE  1 
ATOM   6308 C CZ  . ARG C 1 221 ? -62.147 27.444  47.994  1   32.52  ? 217 ARG C CZ  1 
ATOM   6309 N NH1 . ARG C 1 221 ? -61.742 26.718  49.02   1   31.03  ? 217 ARG C NH1 1 
ATOM   6310 N NH2 . ARG C 1 221 ? -62.71  28.621  48.203  1   32.58  ? 217 ARG C NH2 1 
ATOM   6311 N N   . THR C 1 222 ? -63.335 26.153  40.434  1   30.19  ? 218 THR C N   1 
ATOM   6312 C CA  . THR C 1 222 ? -63.221 26.537  39.033  1   29.18  ? 218 THR C CA  1 
ATOM   6313 C C   . THR C 1 222 ? -64.174 25.736  38.145  1   28.7   ? 218 THR C C   1 
ATOM   6314 O O   . THR C 1 222 ? -64.715 26.287  37.188  1   30.91  ? 218 THR C O   1 
ATOM   6315 C CB  . THR C 1 222 ? -61.769 26.375  38.589  1   30.86  ? 218 THR C CB  1 
ATOM   6316 O OG1 . THR C 1 222 ? -61.069 27.44   39.219  1   29.28  ? 218 THR C OG1 1 
ATOM   6317 C CG2 . THR C 1 222 ? -61.59  26.494  37.085  1   31.38  ? 218 THR C CG2 1 
ATOM   6318 N N   . LEU C 1 223 ? -64.355 24.441  38.433  1   27.58  ? 219 LEU C N   1 
ATOM   6319 C CA  . LEU C 1 223 ? -65.142 23.584  37.55   1   28.98  ? 219 LEU C CA  1 
ATOM   6320 C C   . LEU C 1 223 ? -66.502 23.217  38.146  1   32.41  ? 219 LEU C C   1 
ATOM   6321 O O   . LEU C 1 223 ? -67.262 22.498  37.497  1   31.92  ? 219 LEU C O   1 
ATOM   6322 C CB  . LEU C 1 223 ? -64.374 22.31   37.212  1   26.49  ? 219 LEU C CB  1 
ATOM   6323 C CG  . LEU C 1 223 ? -62.962 22.488  36.633  1   25.77  ? 219 LEU C CG  1 
ATOM   6324 C CD1 . LEU C 1 223 ? -62.197 21.181  36.716  1   21.82  ? 219 LEU C CD1 1 
ATOM   6325 C CD2 . LEU C 1 223 ? -62.962 23.004  35.203  1   22.3   ? 219 LEU C CD2 1 
ATOM   6326 N N   . GLY C 1 224 ? -66.779 23.679  39.376  1   35.65  ? 220 GLY C N   1 
ATOM   6327 C CA  . GLY C 1 224 ? -68.001 23.37   40.108  1   34.87  ? 220 GLY C CA  1 
ATOM   6328 C C   . GLY C 1 224 ? -67.84  22.029  40.81   1   35.52  ? 220 GLY C C   1 
ATOM   6329 O O   . GLY C 1 224 ? -67.154 21.151  40.291  1   34.96  ? 220 GLY C O   1 
ATOM   6330 N N   . THR C 1 225 ? -68.446 21.898  41.995  1   35.36  ? 221 THR C N   1 
ATOM   6331 C CA  . THR C 1 225 ? -68.293 20.679  42.778  1   38.3   ? 221 THR C CA  1 
ATOM   6332 C C   . THR C 1 225 ? -69.02  19.558  42.048  1   39.14  ? 221 THR C C   1 
ATOM   6333 O O   . THR C 1 225 ? -70.213 19.685  41.785  1   36.95  ? 221 THR C O   1 
ATOM   6334 C CB  . THR C 1 225 ? -68.839 20.844  44.199  1   35.48  ? 221 THR C CB  1 
ATOM   6335 O OG1 . THR C 1 225 ? -68.421 22.136  44.636  1   31.74  ? 221 THR C OG1 1 
ATOM   6336 C CG2 . THR C 1 225 ? -68.368 19.745  45.137  1   33.19  ? 221 THR C CG2 1 
ATOM   6337 N N   . PRO C 1 226 ? -68.333 18.438  41.722  1   43.66  ? 222 PRO C N   1 
ATOM   6338 C CA  . PRO C 1 226 ? -68.96  17.358  40.953  1   47.18  ? 222 PRO C CA  1 
ATOM   6339 C C   . PRO C 1 226 ? -70.09  16.704  41.756  1   49.15  ? 222 PRO C C   1 
ATOM   6340 O O   . PRO C 1 226 ? -70.05  16.716  42.989  1   44.47  ? 222 PRO C O   1 
ATOM   6341 C CB  . PRO C 1 226 ? -67.771 16.406  40.656  1   48.05  ? 222 PRO C CB  1 
ATOM   6342 C CG  . PRO C 1 226 ? -66.799 16.652  41.805  1   47.06  ? 222 PRO C CG  1 
ATOM   6343 C CD  . PRO C 1 226 ? -66.936 18.146  42.107  1   44.67  ? 222 PRO C CD  1 
ATOM   6344 N N   . ASP C 1 227 ? -71.106 16.188  41.043  1   49.51  ? 223 ASP C N   1 
ATOM   6345 C CA  . ASP C 1 227 ? -72.181 15.405  41.635  1   45.09  ? 223 ASP C CA  1 
ATOM   6346 C C   . ASP C 1 227 ? -72.349 14.109  40.838  1   44.91  ? 223 ASP C C   1 
ATOM   6347 O O   . ASP C 1 227 ? -71.682 13.899  39.819  1   42.58  ? 223 ASP C O   1 
ATOM   6348 C CB  . ASP C 1 227 ? -73.466 16.217  41.69   1   44.66  ? 223 ASP C CB  1 
ATOM   6349 C CG  . ASP C 1 227 ? -73.951 16.78   40.357  1   50.67  ? 223 ASP C CG  1 
ATOM   6350 O OD1 . ASP C 1 227 ? -73.452 16.348  39.273  1   55.33  ? 223 ASP C OD1 1 
ATOM   6351 O OD2 . ASP C 1 227 ? -74.808 17.673  40.413  1   51.68  ? 223 ASP C OD2 1 
ATOM   6352 N N   . GLU C 1 228 ? -73.302 13.271  41.276  1   44.75  ? 224 GLU C N   1 
ATOM   6353 C CA  . GLU C 1 228 ? -73.575 11.982  40.662  1   43.97  ? 224 GLU C CA  1 
ATOM   6354 C C   . GLU C 1 228 ? -74.189 12.133  39.267  1   48.83  ? 224 GLU C C   1 
ATOM   6355 O O   . GLU C 1 228 ? -74.357 11.135  38.571  1   55.16  ? 224 GLU C O   1 
ATOM   6356 C CB  . GLU C 1 228 ? -74.497 11.188  41.588  1   41.66  ? 224 GLU C CB  1 
ATOM   6357 C CG  . GLU C 1 228 ? -73.816 10.71   42.865  1   41.58  ? 224 GLU C CG  1 
ATOM   6358 C CD  . GLU C 1 228 ? -72.774 9.627   42.658  1   42.38  ? 224 GLU C CD  1 
ATOM   6359 O OE1 . GLU C 1 228 ? -73.131 8.667   41.938  1   41.12  ? 224 GLU C OE1 1 
ATOM   6360 O OE2 . GLU C 1 228 ? -71.65  9.72    43.217  1   45.33  ? 224 GLU C OE2 1 
ATOM   6361 N N   . VAL C 1 229 ? -74.519 13.364  38.853  1   50.73  ? 225 VAL C N   1 
ATOM   6362 C CA  . VAL C 1 229 ? -75.049 13.604  37.515  1   50.66  ? 225 VAL C CA  1 
ATOM   6363 C C   . VAL C 1 229 ? -73.885 13.971  36.586  1   46.84  ? 225 VAL C C   1 
ATOM   6364 O O   . VAL C 1 229 ? -73.898 13.637  35.405  1   44.49  ? 225 VAL C O   1 
ATOM   6365 C CB  . VAL C 1 229 ? -76.207 14.63   37.452  1   49.45  ? 225 VAL C CB  1 
ATOM   6366 C CG1 . VAL C 1 229 ? -76.784 14.91   38.836  1   51.3   ? 225 VAL C CG1 1 
ATOM   6367 C CG2 . VAL C 1 229 ? -75.805 15.953  36.807  1   45.22  ? 225 VAL C CG2 1 
ATOM   6368 N N   . VAL C 1 230 ? -72.881 14.67   37.127  1   43.52  ? 226 VAL C N   1 
ATOM   6369 C CA  . VAL C 1 230 ? -71.688 15.008  36.37   1   48.03  ? 226 VAL C CA  1 
ATOM   6370 C C   . VAL C 1 230 ? -70.721 13.817  36.38   1   48.07  ? 226 VAL C C   1 
ATOM   6371 O O   . VAL C 1 230 ? -70.16  13.436  35.346  1   46.22  ? 226 VAL C O   1 
ATOM   6372 C CB  . VAL C 1 230 ? -71.032 16.292  36.925  1   50.38  ? 226 VAL C CB  1 
ATOM   6373 C CG1 . VAL C 1 230 ? -69.587 16.426  36.466  1   45.75  ? 226 VAL C CG1 1 
ATOM   6374 C CG2 . VAL C 1 230 ? -71.835 17.55   36.581  1   48.28  ? 226 VAL C CG2 1 
ATOM   6375 N N   . TRP C 1 231 ? -70.53  13.245  37.573  1   45.99  ? 227 TRP C N   1 
ATOM   6376 C CA  . TRP C 1 231 ? -69.546 12.205  37.811  1   42.09  ? 227 TRP C CA  1 
ATOM   6377 C C   . TRP C 1 231 ? -70.175 11.124  38.684  1   45.27  ? 227 TRP C C   1 
ATOM   6378 O O   . TRP C 1 231 ? -70.016 11.115  39.904  1   48.13  ? 227 TRP C O   1 
ATOM   6379 C CB  . TRP C 1 231 ? -68.296 12.818  38.46   1   37.79  ? 227 TRP C CB  1 
ATOM   6380 C CG  . TRP C 1 231 ? -67.126 11.881  38.59   1   37.86  ? 227 TRP C CG  1 
ATOM   6381 C CD1 . TRP C 1 231 ? -67.048 10.6    38.132  1   37.46  ? 227 TRP C CD1 1 
ATOM   6382 C CD2 . TRP C 1 231 ? -65.845 12.173  39.195  1   39.81  ? 227 TRP C CD2 1 
ATOM   6383 N NE1 . TRP C 1 231 ? -65.819 10.073  38.418  1   38.69  ? 227 TRP C NE1 1 
ATOM   6384 C CE2 . TRP C 1 231 ? -65.06  11.006  39.072  1   39.2   ? 227 TRP C CE2 1 
ATOM   6385 C CE3 . TRP C 1 231 ? -65.289 13.294  39.83   1   42.86  ? 227 TRP C CE3 1 
ATOM   6386 C CZ2 . TRP C 1 231 ? -63.755 10.925  39.561  1   41.26  ? 227 TRP C CZ2 1 
ATOM   6387 C CZ3 . TRP C 1 231 ? -63.996 13.216  40.308  1   43.53  ? 227 TRP C CZ3 1 
ATOM   6388 C CH2 . TRP C 1 231 ? -63.241 12.045  40.178  1   44.24  ? 227 TRP C CH2 1 
ATOM   6389 N N   . PRO C 1 232 ? -70.941 10.186  38.087  1   47.46  ? 228 PRO C N   1 
ATOM   6390 C CA  . PRO C 1 232 ? -71.506 9.06    38.839  1   46.99  ? 228 PRO C CA  1 
ATOM   6391 C C   . PRO C 1 232 ? -70.419 8.353   39.643  1   45.87  ? 228 PRO C C   1 
ATOM   6392 O O   . PRO C 1 232 ? -69.346 8.08    39.102  1   47     ? 228 PRO C O   1 
ATOM   6393 C CB  . PRO C 1 232 ? -72.048 8.134   37.733  1   45.55  ? 228 PRO C CB  1 
ATOM   6394 C CG  . PRO C 1 232 ? -72.314 9.052   36.558  1   45.07  ? 228 PRO C CG  1 
ATOM   6395 C CD  . PRO C 1 232 ? -71.269 10.147  36.654  1   47.94  ? 228 PRO C CD  1 
ATOM   6396 N N   . GLY C 1 233 ? -70.71  8.057   40.917  1   42.54  ? 229 GLY C N   1 
ATOM   6397 C CA  . GLY C 1 233 ? -69.772 7.363   41.788  1   48.59  ? 229 GLY C CA  1 
ATOM   6398 C C   . GLY C 1 233 ? -68.892 8.291   42.633  1   50.21  ? 229 GLY C C   1 
ATOM   6399 O O   . GLY C 1 233 ? -68.323 7.841   43.63   1   55.11  ? 229 GLY C O   1 
ATOM   6400 N N   . VAL C 1 234 ? -68.785 9.571   42.239  1   45.49  ? 230 VAL C N   1 
ATOM   6401 C CA  . VAL C 1 234 ? -67.974 10.55   42.948  1   43.19  ? 230 VAL C CA  1 
ATOM   6402 C C   . VAL C 1 234 ? -68.29  10.52   44.447  1   46.53  ? 230 VAL C C   1 
ATOM   6403 O O   . VAL C 1 234 ? -67.382 10.394  45.271  1   50.67  ? 230 VAL C O   1 
ATOM   6404 C CB  . VAL C 1 234 ? -68.07  11.979  42.373  1   39.87  ? 230 VAL C CB  1 
ATOM   6405 C CG1 . VAL C 1 234 ? -69.471 12.554  42.479  1   38.94  ? 230 VAL C CG1 1 
ATOM   6406 C CG2 . VAL C 1 234 ? -67.07  12.938  43.01   1   37.91  ? 230 VAL C CG2 1 
ATOM   6407 N N   . THR C 1 235 ? -69.582 10.602  44.795  1   43.92  ? 231 THR C N   1 
ATOM   6408 C CA  . THR C 1 235 ? -70.011 10.73   46.182  1   47.66  ? 231 THR C CA  1 
ATOM   6409 C C   . THR C 1 235 ? -69.695 9.448   46.966  1   48.53  ? 231 THR C C   1 
ATOM   6410 O O   . THR C 1 235 ? -69.787 9.432   48.198  1   43.34  ? 231 THR C O   1 
ATOM   6411 C CB  . THR C 1 235 ? -71.497 11.103  46.262  1   46.36  ? 231 THR C CB  1 
ATOM   6412 O OG1 . THR C 1 235 ? -72.262 9.969   45.853  1   45.13  ? 231 THR C OG1 1 
ATOM   6413 C CG2 . THR C 1 235 ? -71.837 12.337  45.445  1   43.52  ? 231 THR C CG2 1 
ATOM   6414 N N   . SER C 1 236 ? -69.339 8.373   46.244  1   49.37  ? 232 SER C N   1 
ATOM   6415 C CA  . SER C 1 236 ? -69.005 7.091   46.856  1   52.72  ? 232 SER C CA  1 
ATOM   6416 C C   . SER C 1 236 ? -67.491 6.867   46.836  1   51.88  ? 232 SER C C   1 
ATOM   6417 O O   . SER C 1 236 ? -67.007 5.754   47.037  1   50.47  ? 232 SER C O   1 
ATOM   6418 C CB  . SER C 1 236 ? -69.742 5.944   46.188  1   52.73  ? 232 SER C CB  1 
ATOM   6419 O OG  . SER C 1 236 ? -69.147 5.63    44.935  1   60.9   ? 232 SER C OG  1 
ATOM   6420 N N   . MET C 1 237 ? -66.754 7.949   46.589  1   51.69  ? 233 MET C N   1 
ATOM   6421 C CA  . MET C 1 237 ? -65.277 7.846   46.557  1   52.93  ? 233 MET C CA  1 
ATOM   6422 C C   . MET C 1 237 ? -64.739 7.773   47.987  1   50.25  ? 233 MET C C   1 
ATOM   6423 O O   . MET C 1 237 ? -65.274 8.468   48.866  1   47.96  ? 233 MET C O   1 
ATOM   6424 C CB  . MET C 1 237 ? -64.615 9.071   45.918  1   58.34  ? 233 MET C CB  1 
ATOM   6425 C CG  . MET C 1 237 ? -64.731 9.22    44.416  1   61.88  ? 233 MET C CG  1 
ATOM   6426 S SD  . MET C 1 237 ? -64.731 7.706   43.444  1   67.31  ? 233 MET C SD  1 
ATOM   6427 C CE  . MET C 1 237 ? -65.279 8.377   41.869  1   65.92  ? 233 MET C CE  1 
ATOM   6428 N N   . PRO C 1 238 ? -63.699 6.963   48.246  1   46.23  ? 234 PRO C N   1 
ATOM   6429 C CA  . PRO C 1 238 ? -63.045 6.917   49.557  1   43.45  ? 234 PRO C CA  1 
ATOM   6430 C C   . PRO C 1 238 ? -62.881 8.259   50.278  1   39.99  ? 234 PRO C C   1 
ATOM   6431 O O   . PRO C 1 238 ? -63.27  8.395   51.434  1   38.71  ? 234 PRO C O   1 
ATOM   6432 C CB  . PRO C 1 238 ? -61.67  6.289   49.197  1   47.94  ? 234 PRO C CB  1 
ATOM   6433 C CG  . PRO C 1 238 ? -61.953 5.374   48.027  1   46.43  ? 234 PRO C CG  1 
ATOM   6434 C CD  . PRO C 1 238 ? -63.061 6.066   47.26   1   46.79  ? 234 PRO C CD  1 
ATOM   6435 N N   . ASP C 1 239 ? -62.301 9.247   49.587  1   40     ? 235 ASP C N   1 
ATOM   6436 C CA  . ASP C 1 239 ? -61.94  10.515  50.202  1   44.95  ? 235 ASP C CA  1 
ATOM   6437 C C   . ASP C 1 239 ? -62.936 11.615  49.855  1   49.93  ? 235 ASP C C   1 
ATOM   6438 O O   . ASP C 1 239 ? -62.692 12.782  50.175  1   51.95  ? 235 ASP C O   1 
ATOM   6439 C CB  . ASP C 1 239 ? -60.511 10.92   49.879  1   46.1   ? 235 ASP C CB  1 
ATOM   6440 C CG  . ASP C 1 239 ? -59.457 10.061  50.555  1   47.27  ? 235 ASP C CG  1 
ATOM   6441 O OD1 . ASP C 1 239 ? -59.581 9.879   51.784  1   49.97  ? 235 ASP C OD1 1 
ATOM   6442 O OD2 . ASP C 1 239 ? -58.547 9.571   49.847  1   53.08  ? 235 ASP C OD2 1 
ATOM   6443 N N   . TYR C 1 240 ? -64.054 11.242  49.214  1   50.61  ? 236 TYR C N   1 
ATOM   6444 C CA  . TYR C 1 240 ? -65.142 12.183  48.984  1   47.46  ? 236 TYR C CA  1 
ATOM   6445 C C   . TYR C 1 240 ? -65.757 12.569  50.335  1   46.43  ? 236 TYR C C   1 
ATOM   6446 O O   . TYR C 1 240 ? -65.971 11.71   51.187  1   44.56  ? 236 TYR C O   1 
ATOM   6447 C CB  . TYR C 1 240 ? -66.186 11.585  48.029  1   46.41  ? 236 TYR C CB  1 
ATOM   6448 C CG  . TYR C 1 240 ? -67.321 12.558  47.744  1   44.38  ? 236 TYR C CG  1 
ATOM   6449 C CD1 . TYR C 1 240 ? -68.422 12.642  48.595  1   44.75  ? 236 TYR C CD1 1 
ATOM   6450 C CD2 . TYR C 1 240 ? -67.254 13.44   46.669  1   43.78  ? 236 TYR C CD2 1 
ATOM   6451 C CE1 . TYR C 1 240 ? -69.448 13.547  48.362  1   46.12  ? 236 TYR C CE1 1 
ATOM   6452 C CE2 . TYR C 1 240 ? -68.268 14.354  46.429  1   44.2   ? 236 TYR C CE2 1 
ATOM   6453 C CZ  . TYR C 1 240 ? -69.367 14.409  47.275  1   48.82  ? 236 TYR C CZ  1 
ATOM   6454 O OH  . TYR C 1 240 ? -70.357 15.33   47.048  1   50.65  ? 236 TYR C OH  1 
ATOM   6455 N N   . LYS C 1 241 ? -66.078 13.857  50.514  1   45.29  ? 237 LYS C N   1 
ATOM   6456 C CA  . LYS C 1 241 ? -66.664 14.334  51.761  1   46.63  ? 237 LYS C CA  1 
ATOM   6457 C C   . LYS C 1 241 ? -67.989 15.038  51.461  1   45.69  ? 237 LYS C C   1 
ATOM   6458 O O   . LYS C 1 241 ? -67.995 16.059  50.76   1   41.2   ? 237 LYS C O   1 
ATOM   6459 C CB  . LYS C 1 241 ? -65.696 15.27   52.5    1   49.7   ? 237 LYS C CB  1 
ATOM   6460 C CG  . LYS C 1 241 ? -64.339 14.673  52.851  1   53.96  ? 237 LYS C CG  1 
ATOM   6461 C CD  . LYS C 1 241 ? -63.207 15.696  52.807  1   58.84  ? 237 LYS C CD  1 
ATOM   6462 C CE  . LYS C 1 241 ? -63.462 17.07   53.377  1   58.3   ? 237 LYS C CE  1 
ATOM   6463 N NZ  . LYS C 1 241 ? -63.117 17.179  54.799  1   49.51  ? 237 LYS C NZ  1 
ATOM   6464 N N   . PRO C 1 242 ? -69.128 14.522  52.002  1   47.86  ? 238 PRO C N   1 
ATOM   6465 C CA  . PRO C 1 242 ? -70.444 15.145  51.818  1   48.35  ? 238 PRO C CA  1 
ATOM   6466 C C   . PRO C 1 242 ? -70.514 16.655  52.075  1   48.25  ? 238 PRO C C   1 
ATOM   6467 O O   . PRO C 1 242 ? -71.384 17.337  51.53   1   47.3   ? 238 PRO C O   1 
ATOM   6468 C CB  . PRO C 1 242 ? -71.418 14.359  52.737  1   42.71  ? 238 PRO C CB  1 
ATOM   6469 C CG  . PRO C 1 242 ? -70.666 13.127  53.212  1   40.55  ? 238 PRO C CG  1 
ATOM   6470 C CD  . PRO C 1 242 ? -69.204 13.308  52.837  1   45.73  ? 238 PRO C CD  1 
ATOM   6471 N N   . SER C 1 243 ? -69.588 17.17   52.896  1   46.99  ? 239 SER C N   1 
ATOM   6472 C CA  . SER C 1 243 ? -69.594 18.56   53.334  1   44.97  ? 239 SER C CA  1 
ATOM   6473 C C   . SER C 1 243 ? -68.926 19.508  52.326  1   46.68  ? 239 SER C C   1 
ATOM   6474 O O   . SER C 1 243 ? -68.965 20.725  52.511  1   52.55  ? 239 SER C O   1 
ATOM   6475 C CB  . SER C 1 243 ? -69.006 18.677  54.72   1   41.24  ? 239 SER C CB  1 
ATOM   6476 O OG  . SER C 1 243 ? -67.855 17.848  54.839  1   42.92  ? 239 SER C OG  1 
ATOM   6477 N N   . PHE C 1 244 ? -68.338 18.98   51.244  1   44.22  ? 240 PHE C N   1 
ATOM   6478 C CA  . PHE C 1 244 ? -67.767 19.837  50.21   1   45.15  ? 240 PHE C CA  1 
ATOM   6479 C C   . PHE C 1 244 ? -68.731 20.984  49.866  1   44.69  ? 240 PHE C C   1 
ATOM   6480 O O   . PHE C 1 244 ? -69.868 20.729  49.44   1   43.76  ? 240 PHE C O   1 
ATOM   6481 C CB  . PHE C 1 244 ? -67.439 19.048  48.938  1   45.35  ? 240 PHE C CB  1 
ATOM   6482 C CG  . PHE C 1 244 ? -66.258 18.094  49.008  1   49.06  ? 240 PHE C CG  1 
ATOM   6483 C CD1 . PHE C 1 244 ? -65.131 18.394  49.768  1   49.94  ? 240 PHE C CD1 1 
ATOM   6484 C CD2 . PHE C 1 244 ? -66.274 16.898  48.289  1   51.75  ? 240 PHE C CD2 1 
ATOM   6485 C CE1 . PHE C 1 244 ? -64.05  17.52   49.809  1   53.36  ? 240 PHE C CE1 1 
ATOM   6486 C CE2 . PHE C 1 244 ? -65.194 16.018  48.338  1   53.05  ? 240 PHE C CE2 1 
ATOM   6487 C CZ  . PHE C 1 244 ? -64.076 16.337  49.093  1   51.64  ? 240 PHE C CZ  1 
ATOM   6488 N N   . PRO C 1 245 ? -68.309 22.279  49.992  1   41.64  ? 241 PRO C N   1 
ATOM   6489 C CA  . PRO C 1 245 ? -69.121 23.412  49.532  1   39.6   ? 241 PRO C CA  1 
ATOM   6490 C C   . PRO C 1 245 ? -69.534 23.127  48.084  1   42.78  ? 241 PRO C C   1 
ATOM   6491 O O   . PRO C 1 245 ? -68.8   22.457  47.357  1   41.67  ? 241 PRO C O   1 
ATOM   6492 C CB  . PRO C 1 245 ? -68.179 24.635  49.634  1   31.94  ? 241 PRO C CB  1 
ATOM   6493 C CG  . PRO C 1 245 ? -67.187 24.227  50.666  1   32.03  ? 241 PRO C CG  1 
ATOM   6494 C CD  . PRO C 1 245 ? -66.995 22.728  50.482  1   34.99  ? 241 PRO C CD  1 
ATOM   6495 N N   . LYS C 1 246 ? -70.716 23.617  47.676  1   43.65  ? 242 LYS C N   1 
ATOM   6496 C CA  . LYS C 1 246 ? -71.223 23.446  46.318  1   41.59  ? 242 LYS C CA  1 
ATOM   6497 C C   . LYS C 1 246 ? -70.987 24.719  45.497  1   36.41  ? 242 LYS C C   1 
ATOM   6498 O O   . LYS C 1 246 ? -71.83  25.612  45.5    1   33.83  ? 242 LYS C O   1 
ATOM   6499 C CB  . LYS C 1 246 ? -72.697 23.01   46.384  1   45.28  ? 242 LYS C CB  1 
ATOM   6500 C CG  . LYS C 1 246 ? -72.978 21.729  47.18   1   51.29  ? 242 LYS C CG  1 
ATOM   6501 C CD  . LYS C 1 246 ? -72.148 20.527  46.714  1   66.99  ? 242 LYS C CD  1 
ATOM   6502 C CE  . LYS C 1 246 ? -72.254 19.27   47.535  1   68.49  ? 242 LYS C CE  1 
ATOM   6503 N NZ  . LYS C 1 246 ? -72.317 19.549  48.971  1   73.61  ? 242 LYS C NZ  1 
ATOM   6504 N N   . TRP C 1 247 ? -69.838 24.795  44.8    1   37.45  ? 243 TRP C N   1 
ATOM   6505 C CA  . TRP C 1 247 ? -69.464 25.947  43.988  1   34.76  ? 243 TRP C CA  1 
ATOM   6506 C C   . TRP C 1 247 ? -70.054 25.806  42.59   1   37.19  ? 243 TRP C C   1 
ATOM   6507 O O   . TRP C 1 247 ? -70.34  24.698  42.144  1   41.05  ? 243 TRP C O   1 
ATOM   6508 C CB  . TRP C 1 247 ? -67.94  26.129  43.906  1   31.27  ? 243 TRP C CB  1 
ATOM   6509 C CG  . TRP C 1 247 ? -67.265 26.592  45.175  1   30     ? 243 TRP C CG  1 
ATOM   6510 C CD1 . TRP C 1 247 ? -67.247 27.856  45.69   1   26.8   ? 243 TRP C CD1 1 
ATOM   6511 C CD2 . TRP C 1 247 ? -66.475 25.782  46.079  1   26.25  ? 243 TRP C CD2 1 
ATOM   6512 N NE1 . TRP C 1 247 ? -66.513 27.88   46.847  1   25.11  ? 243 TRP C NE1 1 
ATOM   6513 C CE2 . TRP C 1 247 ? -66.03  26.628  47.117  1   25.55  ? 243 TRP C CE2 1 
ATOM   6514 C CE3 . TRP C 1 247 ? -66.112 24.433  46.115  1   24.16  ? 243 TRP C CE3 1 
ATOM   6515 C CZ2 . TRP C 1 247 ? -65.248 26.164  48.178  1   25.76  ? 243 TRP C CZ2 1 
ATOM   6516 C CZ3 . TRP C 1 247 ? -65.342 23.978  47.163  1   26.03  ? 243 TRP C CZ3 1 
ATOM   6517 C CH2 . TRP C 1 247 ? -64.916 24.827  48.191  1   25.69  ? 243 TRP C CH2 1 
ATOM   6518 N N   . ALA C 1 248 ? -70.229 26.948  41.914  1   38.2   ? 244 ALA C N   1 
ATOM   6519 C CA  . ALA C 1 248 ? -70.693 26.977  40.538  1   37.81  ? 244 ALA C CA  1 
ATOM   6520 C C   . ALA C 1 248 ? -69.494 27.024  39.575  1   38.29  ? 244 ALA C C   1 
ATOM   6521 O O   . ALA C 1 248 ? -68.463 27.636  39.883  1   37     ? 244 ALA C O   1 
ATOM   6522 C CB  . ALA C 1 248 ? -71.643 28.145  40.378  1   33.67  ? 244 ALA C CB  1 
ATOM   6523 N N   . ARG C 1 249 ? -69.583 26.341  38.478  1   38.82  ? 245 ARG C N   1 
ATOM   6524 C CA  . ARG C 1 249 ? -68.482 26.311  37.491  1   43.96  ? 245 ARG C CA  1 
ATOM   6525 C C   . ARG C 1 249 ? -68.328 27.705  36.905  1   48.76  ? 245 ARG C C   1 
ATOM   6526 O O   . ARG C 1 249 ? -69.34  28.293  36.485  1   54.07  ? 245 ARG C O   1 
ATOM   6527 C CB  . ARG C 1 249 ? -68.791 25.371  36.326  1   43.04  ? 245 ARG C CB  1 
ATOM   6528 C CG  . ARG C 1 249 ? -67.715 25.361  35.25   1   45.23  ? 245 ARG C CG  1 
ATOM   6529 C CD  . ARG C 1 249 ? -67.927 24.27   34.219  1   45.42  ? 245 ARG C CD  1 
ATOM   6530 N NE  . ARG C 1 249 ? -66.916 23.213  34.333  1   46.89  ? 245 ARG C NE  1 
ATOM   6531 C CZ  . ARG C 1 249 ? -66.451 22.517  33.309  1   40.61  ? 245 ARG C CZ  1 
ATOM   6532 N NH1 . ARG C 1 249 ? -65.694 21.457  33.521  1   36.83  ? 245 ARG C NH1 1 
ATOM   6533 N NH2 . ARG C 1 249 ? -66.745 22.881  32.075  1   36.64  ? 245 ARG C NH2 1 
ATOM   6534 N N   . GLN C 1 250 ? -67.152 28.196  36.846  1   48.39  ? 246 GLN C N   1 
ATOM   6535 C CA  . GLN C 1 250 ? -66.882 29.498  36.259  1   50.47  ? 246 GLN C CA  1 
ATOM   6536 C C   . GLN C 1 250 ? -66.929 29.34   34.737  1   50.61  ? 246 GLN C C   1 
ATOM   6537 O O   . GLN C 1 250 ? -66.589 28.275  34.222  1   48.85  ? 246 GLN C O   1 
ATOM   6538 C CB  . GLN C 1 250 ? -65.524 30.008  36.751  1   53.59  ? 246 GLN C CB  1 
ATOM   6539 C CG  . GLN C 1 250 ? -65.192 29.676  38.204  1   58.24  ? 246 GLN C CG  1 
ATOM   6540 C CD  . GLN C 1 250 ? -63.901 30.318  38.665  1   64.05  ? 246 GLN C CD  1 
ATOM   6541 O OE1 . GLN C 1 250 ? -63.286 31.115  37.946  1   64.57  ? 246 GLN C OE1 1 
ATOM   6542 N NE2 . GLN C 1 250 ? -63.487 30.002  39.884  1   63.25  ? 246 GLN C NE2 1 
ATOM   6543 N N   . ASP C 1 251 ? -67.384 30.379  34.014  1   55.93  ? 247 ASP C N   1 
ATOM   6544 C CA  . ASP C 1 251 ? -67.238 30.399  32.561  1   57.88  ? 247 ASP C CA  1 
ATOM   6545 C C   . ASP C 1 251 ? -65.759 30.267  32.205  1   54.89  ? 247 ASP C C   1 
ATOM   6546 O O   . ASP C 1 251 ? -64.894 30.917  32.796  1   51.22  ? 247 ASP C O   1 
ATOM   6547 C CB  . ASP C 1 251 ? -67.697 31.702  31.927  1   63.92  ? 247 ASP C CB  1 
ATOM   6548 C CG  . ASP C 1 251 ? -69.194 31.948  31.873  1   69.24  ? 247 ASP C CG  1 
ATOM   6549 O OD1 . ASP C 1 251 ? -69.857 31.337  31.016  1   73.71  ? 247 ASP C OD1 1 
ATOM   6550 O OD2 . ASP C 1 251 ? -69.673 32.755  32.688  1   74.09  ? 247 ASP C OD2 1 
ATOM   6551 N N   . PHE C 1 252 ? -65.47  29.417  31.222  1   55.83  ? 248 PHE C N   1 
ATOM   6552 C CA  . PHE C 1 252 ? -64.092 29.256  30.791  1   61.41  ? 248 PHE C CA  1 
ATOM   6553 C C   . PHE C 1 252 ? -63.582 30.561  30.185  1   62.27  ? 248 PHE C C   1 
ATOM   6554 O O   . PHE C 1 252 ? -62.372 30.758  30.072  1   62.57  ? 248 PHE C O   1 
ATOM   6555 C CB  . PHE C 1 252 ? -63.97  28.07   29.832  1   59.99  ? 248 PHE C CB  1 
ATOM   6556 C CG  . PHE C 1 252 ? -63.751 26.729  30.518  1   60.63  ? 248 PHE C CG  1 
ATOM   6557 C CD1 . PHE C 1 252 ? -64.538 26.323  31.596  1   55.91  ? 248 PHE C CD1 1 
ATOM   6558 C CD2 . PHE C 1 252 ? -62.736 25.884  30.081  1   57.79  ? 248 PHE C CD2 1 
ATOM   6559 C CE1 . PHE C 1 252 ? -64.304 25.107  32.212  1   57.25  ? 248 PHE C CE1 1 
ATOM   6560 C CE2 . PHE C 1 252 ? -62.51  24.663  30.693  1   56     ? 248 PHE C CE2 1 
ATOM   6561 C CZ  . PHE C 1 252 ? -63.298 24.278  31.755  1   55.46  ? 248 PHE C CZ  1 
ATOM   6562 N N   . SER C 1 253 ? -64.525 31.428  29.789  1   58.57  ? 249 SER C N   1 
ATOM   6563 C CA  . SER C 1 253 ? -64.259 32.761  29.263  1   55.11  ? 249 SER C CA  1 
ATOM   6564 C C   . SER C 1 253 ? -63.535 33.615  30.305  1   55.97  ? 249 SER C C   1 
ATOM   6565 O O   . SER C 1 253 ? -62.837 34.57   29.961  1   55.95  ? 249 SER C O   1 
ATOM   6566 C CB  . SER C 1 253 ? -65.534 33.408  28.795  1   50.01  ? 249 SER C CB  1 
ATOM   6567 O OG  . SER C 1 253 ? -66.173 32.544  27.864  1   51.79  ? 249 SER C OG  1 
ATOM   6568 N N   . LYS C 1 254 ? -63.654 33.223  31.575  1   54.59  ? 250 LYS C N   1 
ATOM   6569 C CA  . LYS C 1 254 ? -62.993 33.954  32.639  1   55.22  ? 250 LYS C CA  1 
ATOM   6570 C C   . LYS C 1 254 ? -61.752 33.165  33.03   1   47.31  ? 250 LYS C C   1 
ATOM   6571 O O   . LYS C 1 254 ? -60.696 33.747  33.246  1   44.89  ? 250 LYS C O   1 
ATOM   6572 C CB  . LYS C 1 254 ? -63.944 34.166  33.824  1   61.91  ? 250 LYS C CB  1 
ATOM   6573 C CG  . LYS C 1 254 ? -65.109 35.091  33.512  1   73.44  ? 250 LYS C CG  1 
ATOM   6574 C CD  . LYS C 1 254 ? -66.087 35.299  34.675  1   75.79  ? 250 LYS C CD  1 
ATOM   6575 C CE  . LYS C 1 254 ? -67.29  36.208  34.541  1   68.21  ? 250 LYS C CE  1 
ATOM   6576 N NZ  . LYS C 1 254 ? -68.132 36.276  35.738  1   65.05  ? 250 LYS C NZ  1 
ATOM   6577 N N   . VAL C 1 255 ? -61.905 31.837  33.079  1   44.88  ? 251 VAL C N   1 
ATOM   6578 C CA  . VAL C 1 255 ? -60.85  30.93   33.499  1   44.51  ? 251 VAL C CA  1 
ATOM   6579 C C   . VAL C 1 255 ? -59.649 31.047  32.566  1   41.9   ? 251 VAL C C   1 
ATOM   6580 O O   . VAL C 1 255 ? -58.514 31.044  33.021  1   41.74  ? 251 VAL C O   1 
ATOM   6581 C CB  . VAL C 1 255 ? -61.363 29.483  33.538  1   49.91  ? 251 VAL C CB  1 
ATOM   6582 C CG1 . VAL C 1 255 ? -60.228 28.48   33.76   1   52.02  ? 251 VAL C CG1 1 
ATOM   6583 C CG2 . VAL C 1 255 ? -62.479 29.336  34.565  1   48     ? 251 VAL C CG2 1 
ATOM   6584 N N   . VAL C 1 256 ? -59.912 31.117  31.263  1   40.27  ? 252 VAL C N   1 
ATOM   6585 C CA  . VAL C 1 256 ? -58.863 31.288  30.275  1   43.88  ? 252 VAL C CA  1 
ATOM   6586 C C   . VAL C 1 256 ? -59.354 32.283  29.222  1   47.92  ? 252 VAL C C   1 
ATOM   6587 O O   . VAL C 1 256 ? -59.829 31.901  28.149  1   48.57  ? 252 VAL C O   1 
ATOM   6588 C CB  . VAL C 1 256 ? -58.407 29.942  29.678  1   44.69  ? 252 VAL C CB  1 
ATOM   6589 C CG1 . VAL C 1 256 ? -57.166 30.119  28.829  1   46.22  ? 252 VAL C CG1 1 
ATOM   6590 C CG2 . VAL C 1 256 ? -58.044 28.944  30.763  1   46.04  ? 252 VAL C CG2 1 
ATOM   6591 N N   . PRO C 1 257 ? -59.288 33.604  29.52   1   50.14  ? 253 PRO C N   1 
ATOM   6592 C CA  . PRO C 1 257 ? -59.773 34.642  28.605  1   47.03  ? 253 PRO C CA  1 
ATOM   6593 C C   . PRO C 1 257 ? -59.173 34.634  27.197  1   49.42  ? 253 PRO C C   1 
ATOM   6594 O O   . PRO C 1 257 ? -59.918 34.794  26.23   1   53.61  ? 253 PRO C O   1 
ATOM   6595 C CB  . PRO C 1 257 ? -59.458 35.952  29.346  1   46.02  ? 253 PRO C CB  1 
ATOM   6596 C CG  . PRO C 1 257 ? -59.376 35.541  30.799  1   47.46  ? 253 PRO C CG  1 
ATOM   6597 C CD  . PRO C 1 257 ? -58.738 34.164  30.767  1   48.95  ? 253 PRO C CD  1 
ATOM   6598 N N   . PRO C 1 258 ? -57.834 34.471  27.009  1   48.49  ? 254 PRO C N   1 
ATOM   6599 C CA  . PRO C 1 258 ? -57.247 34.551  25.668  1   42.54  ? 254 PRO C CA  1 
ATOM   6600 C C   . PRO C 1 258 ? -57.735 33.467  24.714  1   39.46  ? 254 PRO C C   1 
ATOM   6601 O O   . PRO C 1 258 ? -57.535 33.573  23.507  1   41.45  ? 254 PRO C O   1 
ATOM   6602 C CB  . PRO C 1 258 ? -55.717 34.481  25.874  1   41.72  ? 254 PRO C CB  1 
ATOM   6603 C CG  . PRO C 1 258 ? -55.507 34.606  27.373  1   43.98  ? 254 PRO C CG  1 
ATOM   6604 C CD  . PRO C 1 258 ? -56.813 34.22   28.047  1   46.8   ? 254 PRO C CD  1 
ATOM   6605 N N   . LEU C 1 259 ? -58.37  32.428  25.264  1   37.34  ? 255 LEU C N   1 
ATOM   6606 C CA  . LEU C 1 259 ? -58.66  31.231  24.491  1   40.29  ? 255 LEU C CA  1 
ATOM   6607 C C   . LEU C 1 259 ? -59.949 31.412  23.691  1   46.1   ? 255 LEU C C   1 
ATOM   6608 O O   . LEU C 1 259 ? -60.87  32.077  24.161  1   49.27  ? 255 LEU C O   1 
ATOM   6609 C CB  . LEU C 1 259 ? -58.737 30.06   25.464  1   38.21  ? 255 LEU C CB  1 
ATOM   6610 C CG  . LEU C 1 259 ? -58.207 28.727  24.927  1   38.75  ? 255 LEU C CG  1 
ATOM   6611 C CD1 . LEU C 1 259 ? -56.891 28.865  24.169  1   35.46  ? 255 LEU C CD1 1 
ATOM   6612 C CD2 . LEU C 1 259 ? -58.061 27.733  26.06   1   37.39  ? 255 LEU C CD2 1 
ATOM   6613 N N   . ASP C 1 260 ? -59.98  30.843  22.473  1   47.91  ? 256 ASP C N   1 
ATOM   6614 C CA  . ASP C 1 260 ? -61.132 30.903  21.574  1   49.68  ? 256 ASP C CA  1 
ATOM   6615 C C   . ASP C 1 260 ? -62.151 29.842  21.992  1   46.72  ? 256 ASP C C   1 
ATOM   6616 O O   . ASP C 1 260 ? -61.938 29.117  22.961  1   47.14  ? 256 ASP C O   1 
ATOM   6617 C CB  . ASP C 1 260 ? -60.724 30.74   20.111  1   52.49  ? 256 ASP C CB  1 
ATOM   6618 C CG  . ASP C 1 260 ? -59.799 29.556  19.818  1   58.73  ? 256 ASP C CG  1 
ATOM   6619 O OD1 . ASP C 1 260 ? -58.647 29.57   20.312  1   58.78  ? 256 ASP C OD1 1 
ATOM   6620 O OD2 . ASP C 1 260 ? -60.227 28.61   19.115  1   55.37  ? 256 ASP C OD2 1 
ATOM   6621 N N   . GLU C 1 261 ? -63.239 29.721  21.229  1   43.99  ? 257 GLU C N   1 
ATOM   6622 C CA  . GLU C 1 261 ? -64.315 28.787  21.541  1   45.63  ? 257 GLU C CA  1 
ATOM   6623 C C   . GLU C 1 261 ? -63.879 27.316  21.436  1   42.51  ? 257 GLU C C   1 
ATOM   6624 O O   . GLU C 1 261 ? -64.318 26.481  22.228  1   40.72  ? 257 GLU C O   1 
ATOM   6625 C CB  . GLU C 1 261 ? -65.486 29.145  20.625  1   46.39  ? 257 GLU C CB  1 
ATOM   6626 C CG  . GLU C 1 261 ? -66.597 28.103  20.609  1   51.96  ? 257 GLU C CG  1 
ATOM   6627 C CD  . GLU C 1 261 ? -67.627 28.371  19.524  1   65.15  ? 257 GLU C CD  1 
ATOM   6628 O OE1 . GLU C 1 261 ? -67.716 27.584  18.554  1   65.53  ? 257 GLU C OE1 1 
ATOM   6629 O OE2 . GLU C 1 261 ? -68.355 29.379  19.655  1   75.66  ? 257 GLU C OE2 1 
ATOM   6630 N N   . ASP C 1 262 ? -63.077 26.985  20.413  1   42.24  ? 258 ASP C N   1 
ATOM   6631 C CA  . ASP C 1 262 ? -62.539 25.647  20.205  1   40.76  ? 258 ASP C CA  1 
ATOM   6632 C C   . ASP C 1 262 ? -61.584 25.248  21.34   1   39.95  ? 258 ASP C C   1 
ATOM   6633 O O   . ASP C 1 262 ? -61.699 24.172  21.93   1   40.81  ? 258 ASP C O   1 
ATOM   6634 C CB  . ASP C 1 262 ? -61.832 25.579  18.862  1   41.64  ? 258 ASP C CB  1 
ATOM   6635 C CG  . ASP C 1 262 ? -62.713 25.439  17.629  1   43.09  ? 258 ASP C CG  1 
ATOM   6636 O OD1 . ASP C 1 262 ? -63.832 24.912  17.75   1   43.04  ? 258 ASP C OD1 1 
ATOM   6637 O OD2 . ASP C 1 262 ? -62.259 25.854  16.553  1   42.55  ? 258 ASP C OD2 1 
ATOM   6638 N N   . GLY C 1 263 ? -60.618 26.123  21.636  1   36.45  ? 259 GLY C N   1 
ATOM   6639 C CA  . GLY C 1 263 ? -59.689 25.899  22.722  1   31.72  ? 259 GLY C CA  1 
ATOM   6640 C C   . GLY C 1 263 ? -60.42  25.661  24.04   1   34.15  ? 259 GLY C C   1 
ATOM   6641 O O   . GLY C 1 263 ? -60.04  24.773  24.796  1   35.47  ? 259 GLY C O   1 
ATOM   6642 N N   . ARG C 1 264 ? -61.451 26.46   24.328  1   34.66  ? 260 ARG C N   1 
ATOM   6643 C CA  . ARG C 1 264 ? -62.217 26.311  25.562  1   35.99  ? 260 ARG C CA  1 
ATOM   6644 C C   . ARG C 1 264 ? -62.902 24.938  25.595  1   33.87  ? 260 ARG C C   1 
ATOM   6645 O O   . ARG C 1 264 ? -62.961 24.291  26.638  1   35.29  ? 260 ARG C O   1 
ATOM   6646 C CB  . ARG C 1 264 ? -63.186 27.49   25.761  1   37.6   ? 260 ARG C CB  1 
ATOM   6647 C CG  . ARG C 1 264 ? -62.499 28.805  26.119  1   41.56  ? 260 ARG C CG  1 
ATOM   6648 C CD  . ARG C 1 264 ? -63.393 29.952  26.582  1   43.01  ? 260 ARG C CD  1 
ATOM   6649 N NE  . ARG C 1 264 ? -64.668 29.884  25.858  1   47.49  ? 260 ARG C NE  1 
ATOM   6650 C CZ  . ARG C 1 264 ? -64.984 30.536  24.746  1   50.45  ? 260 ARG C CZ  1 
ATOM   6651 N NH1 . ARG C 1 264 ? -64.154 31.432  24.226  1   52.32  ? 260 ARG C NH1 1 
ATOM   6652 N NH2 . ARG C 1 264 ? -66.127 30.263  24.143  1   47.79  ? 260 ARG C NH2 1 
ATOM   6653 N N   . SER C 1 265 ? -63.401 24.492  24.437  1   31.82  ? 261 SER C N   1 
ATOM   6654 C CA  . SER C 1 265 ? -64.096 23.221  24.302  1   30.47  ? 261 SER C CA  1 
ATOM   6655 C C   . SER C 1 265 ? -63.143 22.054  24.565  1   29.55  ? 261 SER C C   1 
ATOM   6656 O O   . SER C 1 265 ? -63.442 21.142  25.335  1   28.84  ? 261 SER C O   1 
ATOM   6657 C CB  . SER C 1 265 ? -64.706 23.106  22.938  1   31.48  ? 261 SER C CB  1 
ATOM   6658 O OG  . SER C 1 265 ? -65.222 21.799  22.743  1   32.4   ? 261 SER C OG  1 
ATOM   6659 N N   . LEU C 1 266 ? -61.989 22.078  23.899  1   26.2   ? 262 LEU C N   1 
ATOM   6660 C CA  . LEU C 1 266 ? -61.008 21.039  24.127  1   27.6   ? 262 LEU C CA  1 
ATOM   6661 C C   . LEU C 1 266 ? -60.526 21.065  25.588  1   29.51  ? 262 LEU C C   1 
ATOM   6662 O O   . LEU C 1 266 ? -60.417 20.024  26.247  1   27.18  ? 262 LEU C O   1 
ATOM   6663 C CB  . LEU C 1 266 ? -59.879 21.194  23.108  1   25.18  ? 262 LEU C CB  1 
ATOM   6664 C CG  . LEU C 1 266 ? -58.66  20.302  23.365  1   25.91  ? 262 LEU C CG  1 
ATOM   6665 C CD1 . LEU C 1 266 ? -59.024 18.817  23.268  1   23.59  ? 262 LEU C CD1 1 
ATOM   6666 C CD2 . LEU C 1 266 ? -57.501 20.667  22.453  1   24.41  ? 262 LEU C CD2 1 
ATOM   6667 N N   . LEU C 1 267 ? -60.236 22.262  26.108  1   30.02  ? 263 LEU C N   1 
ATOM   6668 C CA  . LEU C 1 267 ? -59.78  22.384  27.482  1   28.42  ? 263 LEU C CA  1 
ATOM   6669 C C   . LEU C 1 267 ? -60.775 21.7    28.425  1   30.76  ? 263 LEU C C   1 
ATOM   6670 O O   . LEU C 1 267 ? -60.381 20.877  29.25   1   33.64  ? 263 LEU C O   1 
ATOM   6671 C CB  . LEU C 1 267 ? -59.536 23.843  27.862  1   26.1   ? 263 LEU C CB  1 
ATOM   6672 C CG  . LEU C 1 267 ? -59.114 24.083  29.318  1   25.06  ? 263 LEU C CG  1 
ATOM   6673 C CD1 . LEU C 1 267 ? -57.903 23.229  29.732  1   24.37  ? 263 LEU C CD1 1 
ATOM   6674 C CD2 . LEU C 1 267 ? -58.827 25.549  29.553  1   21.68  ? 263 LEU C CD2 1 
ATOM   6675 N N   . SER C 1 268 ? -62.068 21.995  28.266  1   27.04  ? 264 SER C N   1 
ATOM   6676 C CA  . SER C 1 268 ? -63.048 21.44   29.184  1   26.7   ? 264 SER C CA  1 
ATOM   6677 C C   . SER C 1 268 ? -63.142 19.916  29.058  1   27.42  ? 264 SER C C   1 
ATOM   6678 O O   . SER C 1 268 ? -63.384 19.232  30.041  1   27.27  ? 264 SER C O   1 
ATOM   6679 C CB  . SER C 1 268 ? -64.383 22.099  29.019  1   25.17  ? 264 SER C CB  1 
ATOM   6680 O OG  . SER C 1 268 ? -64.995 21.661  27.825  1   26.71  ? 264 SER C OG  1 
ATOM   6681 N N   . GLN C 1 269 ? -62.947 19.373  27.851  1   27.42  ? 265 GLN C N   1 
ATOM   6682 C CA  . GLN C 1 269 ? -63.036 17.935  27.647  1   26.46  ? 265 GLN C CA  1 
ATOM   6683 C C   . GLN C 1 269 ? -61.831 17.222  28.251  1   27.89  ? 265 GLN C C   1 
ATOM   6684 O O   . GLN C 1 269 ? -61.925 16.055  28.635  1   30     ? 265 GLN C O   1 
ATOM   6685 C CB  . GLN C 1 269 ? -63.129 17.606  26.16   1   25.63  ? 265 GLN C CB  1 
ATOM   6686 C CG  . GLN C 1 269 ? -64.533 17.747  25.593  1   23.41  ? 265 GLN C CG  1 
ATOM   6687 C CD  . GLN C 1 269 ? -64.502 17.611  24.092  1   25.4   ? 265 GLN C CD  1 
ATOM   6688 O OE1 . GLN C 1 269 ? -64.678 18.59   23.369  1   26.78  ? 265 GLN C OE1 1 
ATOM   6689 N NE2 . GLN C 1 269 ? -64.22  16.413  23.599  1   25.59  ? 265 GLN C NE2 1 
ATOM   6690 N N   . MET C 1 270 ? -60.699 17.929  28.299  1   26.19  ? 266 MET C N   1 
ATOM   6691 C CA  . MET C 1 270 ? -59.501 17.422  28.944  1   27.88  ? 266 MET C CA  1 
ATOM   6692 C C   . MET C 1 270 ? -59.673 17.422  30.462  1   27.82  ? 266 MET C C   1 
ATOM   6693 O O   . MET C 1 270 ? -59.042 16.621  31.151  1   28.53  ? 266 MET C O   1 
ATOM   6694 C CB  . MET C 1 270 ? -58.271 18.243  28.533  1   25.92  ? 266 MET C CB  1 
ATOM   6695 C CG  . MET C 1 270 ? -57.855 17.972  27.095  1   26.49  ? 266 MET C CG  1 
ATOM   6696 S SD  . MET C 1 270 ? -56.472 18.961  26.503  1   29.41  ? 266 MET C SD  1 
ATOM   6697 C CE  . MET C 1 270 ? -55.074 18.003  27.108  1   26.16  ? 266 MET C CE  1 
ATOM   6698 N N   . LEU C 1 271 ? -60.516 18.338  30.962  1   28.26  ? 267 LEU C N   1 
ATOM   6699 C CA  . LEU C 1 271 ? -60.684 18.567  32.39   1   29.18  ? 267 LEU C CA  1 
ATOM   6700 C C   . LEU C 1 271 ? -62.017 18.021  32.906  1   30.34  ? 267 LEU C C   1 
ATOM   6701 O O   . LEU C 1 271 ? -62.506 18.452  33.94   1   30.94  ? 267 LEU C O   1 
ATOM   6702 C CB  . LEU C 1 271 ? -60.508 20.055  32.698  1   28     ? 267 LEU C CB  1 
ATOM   6703 C CG  . LEU C 1 271 ? -59.091 20.629  32.529  1   28.48  ? 267 LEU C CG  1 
ATOM   6704 C CD1 . LEU C 1 271 ? -59.054 22.081  32.994  1   28.83  ? 267 LEU C CD1 1 
ATOM   6705 C CD2 . LEU C 1 271 ? -58     19.808  33.228  1   25.58  ? 267 LEU C CD2 1 
ATOM   6706 N N   . HIS C 1 272 ? -62.588 17.027  32.223  1   34.28  ? 268 HIS C N   1 
ATOM   6707 C CA  . HIS C 1 272 ? -63.821 16.415  32.692  1   36.34  ? 268 HIS C CA  1 
ATOM   6708 C C   . HIS C 1 272 ? -63.544 15.688  34.01   1   35.88  ? 268 HIS C C   1 
ATOM   6709 O O   . HIS C 1 272 ? -62.482 15.089  34.176  1   36.39  ? 268 HIS C O   1 
ATOM   6710 C CB  . HIS C 1 272 ? -64.407 15.521  31.594  1   43.83  ? 268 HIS C CB  1 
ATOM   6711 C CG  . HIS C 1 272 ? -65.886 15.312  31.689  1   55.6   ? 268 HIS C CG  1 
ATOM   6712 N ND1 . HIS C 1 272 ? -66.524 14.764  32.79   1   57.29  ? 268 HIS C ND1 1 
ATOM   6713 C CD2 . HIS C 1 272 ? -66.845 15.565  30.783  1   52.81  ? 268 HIS C CD2 1 
ATOM   6714 C CE1 . HIS C 1 272 ? -67.826 14.708  32.558  1   54.73  ? 268 HIS C CE1 1 
ATOM   6715 N NE2 . HIS C 1 272 ? -68.045 15.191  31.348  1   58.26  ? 268 HIS C NE2 1 
ATOM   6716 N N   . TYR C 1 273 ? -64.493 15.779  34.951  1   32.21  ? 269 TYR C N   1 
ATOM   6717 C CA  . TYR C 1 273 ? -64.382 15.134  36.249  1   30.21  ? 269 TYR C CA  1 
ATOM   6718 C C   . TYR C 1 273 ? -64.325 13.619  36.083  1   29.78  ? 269 TYR C C   1 
ATOM   6719 O O   . TYR C 1 273 ? -63.454 12.958  36.653  1   31.13  ? 269 TYR C O   1 
ATOM   6720 C CB  . TYR C 1 273 ? -65.53  15.552  37.175  1   32.36  ? 269 TYR C CB  1 
ATOM   6721 C CG  . TYR C 1 273 ? -65.293 16.859  37.92   1   33.65  ? 269 TYR C CG  1 
ATOM   6722 C CD1 . TYR C 1 273 ? -64.349 16.947  38.938  1   31.33  ? 269 TYR C CD1 1 
ATOM   6723 C CD2 . TYR C 1 273 ? -66.03  17.997  37.623  1   32.98  ? 269 TYR C CD2 1 
ATOM   6724 C CE1 . TYR C 1 273 ? -64.14  18.134  39.625  1   32.55  ? 269 TYR C CE1 1 
ATOM   6725 C CE2 . TYR C 1 273 ? -65.811 19.191  38.3    1   34.43  ? 269 TYR C CE2 1 
ATOM   6726 C CZ  . TYR C 1 273 ? -64.864 19.273  39.308  1   32.33  ? 269 TYR C CZ  1 
ATOM   6727 O OH  . TYR C 1 273 ? -64.653 20.465  39.978  1   34.12  ? 269 TYR C OH  1 
ATOM   6728 N N   . ASP C 1 274 ? -65.262 13.081  35.295  1   28.83  ? 270 ASP C N   1 
ATOM   6729 C CA  . ASP C 1 274 ? -65.404 11.643  35.139  1   28.75  ? 270 ASP C CA  1 
ATOM   6730 C C   . ASP C 1 274 ? -64.26  11.144  34.262  1   29.81  ? 270 ASP C C   1 
ATOM   6731 O O   . ASP C 1 274 ? -64.125 11.587  33.116  1   29.51  ? 270 ASP C O   1 
ATOM   6732 C CB  . ASP C 1 274 ? -66.766 11.269  34.566  1   28.12  ? 270 ASP C CB  1 
ATOM   6733 C CG  . ASP C 1 274 ? -67.075 9.781   34.449  1   29.34  ? 270 ASP C CG  1 
ATOM   6734 O OD1 . ASP C 1 274 ? -66.13  8.944   34.459  1   27.04  ? 270 ASP C OD1 1 
ATOM   6735 O OD2 . ASP C 1 274 ? -68.281 9.465   34.367  1   34.37  ? 270 ASP C OD2 1 
ATOM   6736 N N   . PRO C 1 275 ? -63.4   10.229  34.778  1   29.66  ? 271 PRO C N   1 
ATOM   6737 C CA  . PRO C 1 275 ? -62.292 9.691   33.989  1   28.37  ? 271 PRO C CA  1 
ATOM   6738 C C   . PRO C 1 275 ? -62.78  9.063   32.684  1   30.13  ? 271 PRO C C   1 
ATOM   6739 O O   . PRO C 1 275 ? -62.104 9.154   31.662  1   29.13  ? 271 PRO C O   1 
ATOM   6740 C CB  . PRO C 1 275 ? -61.659 8.669   34.954  1   27.58  ? 271 PRO C CB  1 
ATOM   6741 C CG  . PRO C 1 275 ? -62.023 9.157   36.324  1   27.53  ? 271 PRO C CG  1 
ATOM   6742 C CD  . PRO C 1 275 ? -63.425 9.706   36.157  1   28.73  ? 271 PRO C CD  1 
ATOM   6743 N N   . ASN C 1 276 ? -63.988 8.478   32.716  1   30.11  ? 272 ASN C N   1 
ATOM   6744 C CA  . ASN C 1 276 ? -64.518 7.734   31.588  1   29.09  ? 272 ASN C CA  1 
ATOM   6745 C C   . ASN C 1 276 ? -64.937 8.657   30.447  1   29.42  ? 272 ASN C C   1 
ATOM   6746 O O   . ASN C 1 276 ? -64.981 8.213   29.299  1   27.65  ? 272 ASN C O   1 
ATOM   6747 C CB  . ASN C 1 276 ? -65.692 6.846   31.98   1   32.58  ? 272 ASN C CB  1 
ATOM   6748 C CG  . ASN C 1 276 ? -65.333 5.784   32.997  1   36.73  ? 272 ASN C CG  1 
ATOM   6749 O OD1 . ASN C 1 276 ? -64.429 4.961   32.775  1   33.59  ? 272 ASN C OD1 1 
ATOM   6750 N ND2 . ASN C 1 276 ? -66.052 5.784   34.114  1   39.59  ? 272 ASN C ND2 1 
ATOM   6751 N N   . LYS C 1 277 ? -65.253 9.923   30.76   1   30.83  ? 273 LYS C N   1 
ATOM   6752 C CA  . LYS C 1 277 ? -65.739 10.879  29.77   1   31.7   ? 273 LYS C CA  1 
ATOM   6753 C C   . LYS C 1 277 ? -64.601 11.762  29.26   1   28.14  ? 273 LYS C C   1 
ATOM   6754 O O   . LYS C 1 277 ? -64.729 12.368  28.198  1   28.26  ? 273 LYS C O   1 
ATOM   6755 C CB  . LYS C 1 277 ? -66.763 11.857  30.357  1   36.77  ? 273 LYS C CB  1 
ATOM   6756 C CG  . LYS C 1 277 ? -67.819 11.281  31.29   1   47.12  ? 273 LYS C CG  1 
ATOM   6757 C CD  . LYS C 1 277 ? -69.236 11.148  30.747  1   55.09  ? 273 LYS C CD  1 
ATOM   6758 C CE  . LYS C 1 277 ? -70.213 11.35   31.879  1   58.66  ? 273 LYS C CE  1 
ATOM   6759 N NZ  . LYS C 1 277 ? -71.55  10.87   31.537  1   67.83  ? 273 LYS C NZ  1 
ATOM   6760 N N   . ARG C 1 278 ? -63.525 11.892  30.05   1   25.29  ? 274 ARG C N   1 
ATOM   6761 C CA  . ARG C 1 278 ? -62.36  12.686  29.683  1   22.92  ? 274 ARG C CA  1 
ATOM   6762 C C   . ARG C 1 278 ? -61.879 12.249  28.293  1   22.25  ? 274 ARG C C   1 
ATOM   6763 O O   . ARG C 1 278 ? -61.798 11.058  28.009  1   21.57  ? 274 ARG C O   1 
ATOM   6764 C CB  . ARG C 1 278 ? -61.288 12.491  30.762  1   21.72  ? 274 ARG C CB  1 
ATOM   6765 C CG  . ARG C 1 278 ? -60.278 13.617  30.863  1   22.54  ? 274 ARG C CG  1 
ATOM   6766 C CD  . ARG C 1 278 ? -59.419 13.462  32.1    1   24.27  ? 274 ARG C CD  1 
ATOM   6767 N NE  . ARG C 1 278 ? -60.233 13.452  33.317  1   25.36  ? 274 ARG C NE  1 
ATOM   6768 C CZ  . ARG C 1 278 ? -59.89  12.85   34.46   1   24.7   ? 274 ARG C CZ  1 
ATOM   6769 N NH1 . ARG C 1 278 ? -58.733 12.223  34.562  1   20.69  ? 274 ARG C NH1 1 
ATOM   6770 N NH2 . ARG C 1 278 ? -60.721 12.877  35.493  1   24.68  ? 274 ARG C NH2 1 
ATOM   6771 N N   . ILE C 1 279 ? -61.564 13.213  27.423  1   20.83  ? 275 ILE C N   1 
ATOM   6772 C CA  . ILE C 1 279 ? -61.158 12.908  26.063  1   21.7   ? 275 ILE C CA  1 
ATOM   6773 C C   . ILE C 1 279 ? -59.844 12.127  26.101  1   23.72  ? 275 ILE C C   1 
ATOM   6774 O O   . ILE C 1 279 ? -59.04  12.286  27.015  1   26.16  ? 275 ILE C O   1 
ATOM   6775 C CB  . ILE C 1 279 ? -61.017 14.204  25.243  1   23.35  ? 275 ILE C CB  1 
ATOM   6776 C CG1 . ILE C 1 279 ? -60.988 13.91   23.743  1   23.93  ? 275 ILE C CG1 1 
ATOM   6777 C CG2 . ILE C 1 279 ? -59.797 15.026  25.701  1   25.17  ? 275 ILE C CG2 1 
ATOM   6778 C CD1 . ILE C 1 279 ? -60.981 15.148  22.861  1   24.01  ? 275 ILE C CD1 1 
ATOM   6779 N N   . SER C 1 280 ? -59.63  11.269  25.105  1   23.7   ? 276 SER C N   1 
ATOM   6780 C CA  . SER C 1 280 ? -58.362 10.577  24.953  1   24.82  ? 276 SER C CA  1 
ATOM   6781 C C   . SER C 1 280 ? -57.397 11.487  24.197  1   25.68  ? 276 SER C C   1 
ATOM   6782 O O   . SER C 1 280 ? -57.854 12.417  23.53   1   24.75  ? 276 SER C O   1 
ATOM   6783 C CB  . SER C 1 280 ? -58.559 9.302   24.198  1   24.72  ? 276 SER C CB  1 
ATOM   6784 O OG  . SER C 1 280 ? -58.964 9.599   22.868  1   25.07  ? 276 SER C OG  1 
ATOM   6785 N N   . ALA C 1 281 ? -56.085 11.191  24.286  1   25.35  ? 277 ALA C N   1 
ATOM   6786 C CA  . ALA C 1 281 ? -55.085 11.911  23.515  1   25.52  ? 277 ALA C CA  1 
ATOM   6787 C C   . ALA C 1 281 ? -55.375 11.723  22.026  1   27.86  ? 277 ALA C C   1 
ATOM   6788 O O   . ALA C 1 281 ? -55.26  12.66   21.233  1   29.15  ? 277 ALA C O   1 
ATOM   6789 C CB  . ALA C 1 281 ? -53.7   11.457  23.878  1   21.15  ? 277 ALA C CB  1 
ATOM   6790 N N   . LYS C 1 282 ? -55.807 10.507  21.674  1   27.76  ? 278 LYS C N   1 
ATOM   6791 C CA  . LYS C 1 282 ? -56.138 10.125  20.311  1   28.26  ? 278 LYS C CA  1 
ATOM   6792 C C   . LYS C 1 282 ? -57.303 10.968  19.779  1   30.18  ? 278 LYS C C   1 
ATOM   6793 O O   . LYS C 1 282 ? -57.195 11.573  18.713  1   34.64  ? 278 LYS C O   1 
ATOM   6794 C CB  . LYS C 1 282 ? -56.368 8.613   20.374  1   26.96  ? 278 LYS C CB  1 
ATOM   6795 C CG  . LYS C 1 282 ? -56.66  7.909   19.074  1   29.1   ? 278 LYS C CG  1 
ATOM   6796 C CD  . LYS C 1 282 ? -56.669 6.392   19.209  1   30.13  ? 278 LYS C CD  1 
ATOM   6797 C CE  . LYS C 1 282 ? -55.318 5.775   19.059  1   30.33  ? 278 LYS C CE  1 
ATOM   6798 N NZ  . LYS C 1 282 ? -55.417 4.325   18.836  1   29.95  ? 278 LYS C NZ  1 
ATOM   6799 N N   . ALA C 1 283 ? -58.409 11.051  20.528  1   29.85  ? 279 ALA C N   1 
ATOM   6800 C CA  . ALA C 1 283 ? -59.548 11.861  20.107  1   31.78  ? 279 ALA C CA  1 
ATOM   6801 C C   . ALA C 1 283 ? -59.191 13.345  20.034  1   32.77  ? 279 ALA C C   1 
ATOM   6802 O O   . ALA C 1 283 ? -59.652 14.041  19.133  1   34.32  ? 279 ALA C O   1 
ATOM   6803 C CB  . ALA C 1 283 ? -60.751 11.633  21.002  1   29.7   ? 279 ALA C CB  1 
ATOM   6804 N N   . ALA C 1 284 ? -58.394 13.831  20.997  1   31.42  ? 280 ALA C N   1 
ATOM   6805 C CA  . ALA C 1 284 ? -58.05  15.244  21.069  1   31.68  ? 280 ALA C CA  1 
ATOM   6806 C C   . ALA C 1 284 ? -57.251 15.708  19.848  1   35.06  ? 280 ALA C C   1 
ATOM   6807 O O   . ALA C 1 284 ? -57.309 16.882  19.494  1   41.28  ? 280 ALA C O   1 
ATOM   6808 C CB  . ALA C 1 284 ? -57.338 15.539  22.359  1   29.33  ? 280 ALA C CB  1 
ATOM   6809 N N   . LEU C 1 285 ? -56.502 14.794  19.211  1   36.29  ? 281 LEU C N   1 
ATOM   6810 C CA  . LEU C 1 285 ? -55.742 15.088  17.999  1   36.34  ? 281 LEU C CA  1 
ATOM   6811 C C   . LEU C 1 285 ? -56.667 15.46   16.833  1   38.69  ? 281 LEU C C   1 
ATOM   6812 O O   . LEU C 1 285 ? -56.261 16.153  15.895  1   39.63  ? 281 LEU C O   1 
ATOM   6813 C CB  . LEU C 1 285 ? -54.892 13.864  17.652  1   33.51  ? 281 LEU C CB  1 
ATOM   6814 C CG  . LEU C 1 285 ? -53.647 13.608  18.511  1   31.97  ? 281 LEU C CG  1 
ATOM   6815 C CD1 . LEU C 1 285 ? -52.937 12.357  18.018  1   29.07  ? 281 LEU C CD1 1 
ATOM   6816 C CD2 . LEU C 1 285 ? -52.692 14.803  18.509  1   28.85  ? 281 LEU C CD2 1 
ATOM   6817 N N   . ALA C 1 286 ? -57.91  14.965  16.892  1   37.61  ? 282 ALA C N   1 
ATOM   6818 C CA  . ALA C 1 286 ? -58.918 15.234  15.878  1   35.79  ? 282 ALA C CA  1 
ATOM   6819 C C   . ALA C 1 286 ? -59.734 16.493  16.194  1   39.59  ? 282 ALA C C   1 
ATOM   6820 O O   . ALA C 1 286 ? -60.534 16.91   15.361  1   40.91  ? 282 ALA C O   1 
ATOM   6821 C CB  . ALA C 1 286 ? -59.82  14.032  15.743  1   31.5   ? 282 ALA C CB  1 
ATOM   6822 N N   . HIS C 1 287 ? -59.551 17.096  17.382  1   38.08  ? 283 HIS C N   1 
ATOM   6823 C CA  . HIS C 1 287 ? -60.388 18.213  17.808  1   32.37  ? 283 HIS C CA  1 
ATOM   6824 C C   . HIS C 1 287 ? -60.267 19.384  16.829  1   32.22  ? 283 HIS C C   1 
ATOM   6825 O O   . HIS C 1 287 ? -59.195 19.621  16.274  1   33.72  ? 283 HIS C O   1 
ATOM   6826 C CB  . HIS C 1 287 ? -60.09  18.581  19.267  1   28.71  ? 283 HIS C CB  1 
ATOM   6827 C CG  . HIS C 1 287 ? -61.131 19.452  19.887  1   29.38  ? 283 HIS C CG  1 
ATOM   6828 N ND1 . HIS C 1 287 ? -61.215 20.806  19.632  1   28.18  ? 283 HIS C ND1 1 
ATOM   6829 C CD2 . HIS C 1 287 ? -62.15  19.168  20.728  1   27.42  ? 283 HIS C CD2 1 
ATOM   6830 C CE1 . HIS C 1 287 ? -62.243 21.316  20.31   1   28.21  ? 283 HIS C CE1 1 
ATOM   6831 N NE2 . HIS C 1 287 ? -62.821 20.344  20.975  1   26.63  ? 283 HIS C NE2 1 
ATOM   6832 N N   . PRO C 1 288 ? -61.365 20.133  16.545  1   32.22  ? 284 PRO C N   1 
ATOM   6833 C CA  . PRO C 1 288 ? -61.324 21.27   15.615  1   31.94  ? 284 PRO C CA  1 
ATOM   6834 C C   . PRO C 1 288 ? -60.281 22.341  15.925  1   30.76  ? 284 PRO C C   1 
ATOM   6835 O O   . PRO C 1 288 ? -59.889 23.118  15.054  1   32.29  ? 284 PRO C O   1 
ATOM   6836 C CB  . PRO C 1 288 ? -62.75  21.859  15.672  1   29.33  ? 284 PRO C CB  1 
ATOM   6837 C CG  . PRO C 1 288 ? -63.597 20.69   16.102  1   30.71  ? 284 PRO C CG  1 
ATOM   6838 C CD  . PRO C 1 288 ? -62.727 19.877  17.041  1   31.61  ? 284 PRO C CD  1 
ATOM   6839 N N   . PHE C 1 289 ? -59.876 22.413  17.193  1   27.4   ? 285 PHE C N   1 
ATOM   6840 C CA  . PHE C 1 289 ? -58.897 23.403  17.601  1   27.91  ? 285 PHE C CA  1 
ATOM   6841 C C   . PHE C 1 289 ? -57.597 23.286  16.796  1   28.85  ? 285 PHE C C   1 
ATOM   6842 O O   . PHE C 1 289 ? -56.842 24.259  16.725  1   26.82  ? 285 PHE C O   1 
ATOM   6843 C CB  . PHE C 1 289 ? -58.648 23.209  19.096  1   26.12  ? 285 PHE C CB  1 
ATOM   6844 C CG  . PHE C 1 289 ? -57.57  24.081  19.715  1   23.86  ? 285 PHE C CG  1 
ATOM   6845 C CD1 . PHE C 1 289 ? -57.755 25.456  19.814  1   23.22  ? 285 PHE C CD1 1 
ATOM   6846 C CD2 . PHE C 1 289 ? -56.407 23.512  20.234  1   23.47  ? 285 PHE C CD2 1 
ATOM   6847 C CE1 . PHE C 1 289 ? -56.798 26.247  20.424  1   23.23  ? 285 PHE C CE1 1 
ATOM   6848 C CE2 . PHE C 1 289 ? -55.445 24.302  20.837  1   22.94  ? 285 PHE C CE2 1 
ATOM   6849 C CZ  . PHE C 1 289 ? -55.651 25.662  20.94   1   24.38  ? 285 PHE C CZ  1 
ATOM   6850 N N   . PHE C 1 290 ? -57.352 22.105  16.202  1   30     ? 286 PHE C N   1 
ATOM   6851 C CA  . PHE C 1 290 ? -56.071 21.759  15.596  1   33.83  ? 286 PHE C CA  1 
ATOM   6852 C C   . PHE C 1 290 ? -56.093 21.851  14.063  1   37.09  ? 286 PHE C C   1 
ATOM   6853 O O   . PHE C 1 290 ? -55.032 21.834  13.435  1   38.35  ? 286 PHE C O   1 
ATOM   6854 C CB  . PHE C 1 290 ? -55.646 20.361  16.056  1   31.85  ? 286 PHE C CB  1 
ATOM   6855 C CG  . PHE C 1 290 ? -55.228 20.279  17.513  1   33.27  ? 286 PHE C CG  1 
ATOM   6856 C CD1 . PHE C 1 290 ? -54.186 21.066  18.009  1   32.93  ? 286 PHE C CD1 1 
ATOM   6857 C CD2 . PHE C 1 290 ? -55.895 19.427  18.387  1   32.75  ? 286 PHE C CD2 1 
ATOM   6858 C CE1 . PHE C 1 290 ? -53.807 20.982  19.342  1   31.63  ? 286 PHE C CE1 1 
ATOM   6859 C CE2 . PHE C 1 290 ? -55.505 19.355  19.721  1   33.66  ? 286 PHE C CE2 1 
ATOM   6860 C CZ  . PHE C 1 290 ? -54.47  20.135  20.197  1   30.02  ? 286 PHE C CZ  1 
ATOM   6861 N N   . GLN C 1 291 ? -57.285 21.955  13.463  1   38.35  ? 287 GLN C N   1 
ATOM   6862 C CA  . GLN C 1 291 ? -57.466 21.992  12.017  1   43.77  ? 287 GLN C CA  1 
ATOM   6863 C C   . GLN C 1 291 ? -56.427 22.873  11.319  1   43.61  ? 287 GLN C C   1 
ATOM   6864 O O   . GLN C 1 291 ? -56.027 22.578  10.19   1   47.21  ? 287 GLN C O   1 
ATOM   6865 C CB  . GLN C 1 291 ? -58.871 22.471  11.652  1   49.11  ? 287 GLN C CB  1 
ATOM   6866 C CG  . GLN C 1 291 ? -59.983 21.517  12.078  1   57.42  ? 287 GLN C CG  1 
ATOM   6867 C CD  . GLN C 1 291 ? -61.354 22.166  12.078  1   65.41  ? 287 GLN C CD  1 
ATOM   6868 O OE1 . GLN C 1 291 ? -61.495 23.392  12.205  1   65.92  ? 287 GLN C OE1 1 
ATOM   6869 N NE2 . GLN C 1 291 ? -62.385 21.341  11.946  1   61.99  ? 287 GLN C NE2 1 
ATOM   6870 N N   . ASP C 1 292 ? -55.998 23.952  11.982  1   40.91  ? 288 ASP C N   1 
ATOM   6871 C CA  . ASP C 1 292 ? -55.082 24.911  11.38   1   41.4   ? 288 ASP C CA  1 
ATOM   6872 C C   . ASP C 1 292 ? -53.727 24.92   12.093  1   40.64  ? 288 ASP C C   1 
ATOM   6873 O O   . ASP C 1 292 ? -53.047 25.945  12.089  1   39.66  ? 288 ASP C O   1 
ATOM   6874 C CB  . ASP C 1 292 ? -55.668 26.313  11.422  1   43.49  ? 288 ASP C CB  1 
ATOM   6875 C CG  . ASP C 1 292 ? -56.05  26.804  12.813  1   44.55  ? 288 ASP C CG  1 
ATOM   6876 O OD1 . ASP C 1 292 ? -56.092 25.969  13.739  1   43.21  ? 288 ASP C OD1 1 
ATOM   6877 O OD2 . ASP C 1 292 ? -56.298 28.019  12.962  1   42.18  ? 288 ASP C OD2 1 
ATOM   6878 N N   . VAL C 1 293 ? -53.336 23.787  12.694  1   36.18  ? 289 VAL C N   1 
ATOM   6879 C CA  . VAL C 1 293 ? -52.123 23.744  13.49   1   34.14  ? 289 VAL C CA  1 
ATOM   6880 C C   . VAL C 1 293 ? -50.943 23.902  12.534  1   34.43  ? 289 VAL C C   1 
ATOM   6881 O O   . VAL C 1 293 ? -50.973 23.362  11.433  1   37.62  ? 289 VAL C O   1 
ATOM   6882 C CB  . VAL C 1 293 ? -52.025 22.47   14.363  1   32.36  ? 289 VAL C CB  1 
ATOM   6883 C CG1 . VAL C 1 293 ? -52.039 21.191  13.531  1   32.48  ? 289 VAL C CG1 1 
ATOM   6884 C CG2 . VAL C 1 293 ? -50.838 22.485  15.323  1   27.75  ? 289 VAL C CG2 1 
ATOM   6885 N N   . THR C 1 294 ? -49.945 24.69   12.952  1   32.86  ? 290 THR C N   1 
ATOM   6886 C CA  . THR C 1 294 ? -48.668 24.79   12.262  1   34.32  ? 290 THR C CA  1 
ATOM   6887 C C   . THR C 1 294 ? -47.56  24.455  13.26   1   32.75  ? 290 THR C C   1 
ATOM   6888 O O   . THR C 1 294 ? -47.85  23.988  14.357  1   32.71  ? 290 THR C O   1 
ATOM   6889 C CB  . THR C 1 294 ? -48.494 26.159  11.592  1   36.54  ? 290 THR C CB  1 
ATOM   6890 O OG1 . THR C 1 294 ? -48.658 27.188  12.566  1   36.42  ? 290 THR C OG1 1 
ATOM   6891 C CG2 . THR C 1 294 ? -49.488 26.391  10.468  1   36.82  ? 290 THR C CG2 1 
ATOM   6892 N N   . LYS C 1 295 ? -46.303 24.648  12.854  1   30.69  ? 291 LYS C N   1 
ATOM   6893 C CA  . LYS C 1 295 ? -45.153 24.433  13.716  1   32.39  ? 291 LYS C CA  1 
ATOM   6894 C C   . LYS C 1 295 ? -44.264 25.675  13.699  1   31.91  ? 291 LYS C C   1 
ATOM   6895 O O   . LYS C 1 295 ? -43.231 25.688  13.027  1   33.88  ? 291 LYS C O   1 
ATOM   6896 C CB  . LYS C 1 295 ? -44.35  23.215  13.237  1   36.13  ? 291 LYS C CB  1 
ATOM   6897 C CG  . LYS C 1 295 ? -43.285 22.731  14.225  1   37.08  ? 291 LYS C CG  1 
ATOM   6898 C CD  . LYS C 1 295 ? -42.396 21.604  13.723  1   40.06  ? 291 LYS C CD  1 
ATOM   6899 C CE  . LYS C 1 295 ? -41.534 21.066  14.829  1   46.99  ? 291 LYS C CE  1 
ATOM   6900 N NZ  . LYS C 1 295 ? -40.297 20.44   14.344  1   45.75  ? 291 LYS C NZ  1 
ATOM   6901 N N   . PRO C 1 296 ? -44.617 26.759  14.428  1   31.71  ? 292 PRO C N   1 
ATOM   6902 C CA  . PRO C 1 296 ? -43.737 27.926  14.527  1   33.02  ? 292 PRO C CA  1 
ATOM   6903 C C   . PRO C 1 296 ? -42.464 27.568  15.294  1   34.88  ? 292 PRO C C   1 
ATOM   6904 O O   . PRO C 1 296 ? -42.398 26.529  15.949  1   35.99  ? 292 PRO C O   1 
ATOM   6905 C CB  . PRO C 1 296 ? -44.567 29      15.266  1   31.57  ? 292 PRO C CB  1 
ATOM   6906 C CG  . PRO C 1 296 ? -45.957 28.415  15.418  1   30.86  ? 292 PRO C CG  1 
ATOM   6907 C CD  . PRO C 1 296 ? -45.862 26.917  15.195  1   30.8   ? 292 PRO C CD  1 
ATOM   6908 N N   . VAL C 1 297 ? -41.461 28.446  15.208  1   37.22  ? 293 VAL C N   1 
ATOM   6909 C CA  . VAL C 1 297 ? -40.265 28.291  16.019  1   39.49  ? 293 VAL C CA  1 
ATOM   6910 C C   . VAL C 1 297 ? -40.477 29.115  17.289  1   38.77  ? 293 VAL C C   1 
ATOM   6911 O O   . VAL C 1 297 ? -41.148 30.142  17.252  1   37.35  ? 293 VAL C O   1 
ATOM   6912 C CB  . VAL C 1 297 ? -38.937 28.631  15.294  1   36.33  ? 293 VAL C CB  1 
ATOM   6913 C CG1 . VAL C 1 297 ? -38.915 28.133  13.856  1   29.66  ? 293 VAL C CG1 1 
ATOM   6914 C CG2 . VAL C 1 297 ? -38.585 30.114  15.34   1   36.34  ? 293 VAL C CG2 1 
ATOM   6915 N N   . PRO C 1 298 ? -39.921 28.705  18.452  1   40.23  ? 294 PRO C N   1 
ATOM   6916 C CA  . PRO C 1 298 ? -39.988 29.543  19.654  1   42.5   ? 294 PRO C CA  1 
ATOM   6917 C C   . PRO C 1 298 ? -39.128 30.801  19.486  1   46.24  ? 294 PRO C C   1 
ATOM   6918 O O   . PRO C 1 298 ? -38.106 30.778  18.811  1   48.01  ? 294 PRO C O   1 
ATOM   6919 C CB  . PRO C 1 298 ? -39.426 28.581  20.72   1   40.01  ? 294 PRO C CB  1 
ATOM   6920 C CG  . PRO C 1 298 ? -38.446 27.692  19.957  1   37.7   ? 294 PRO C CG  1 
ATOM   6921 C CD  . PRO C 1 298 ? -39.147 27.462  18.641  1   37.88  ? 294 PRO C CD  1 
ATOM   6922 N N   . HIS C 1 299 ? -39.537 31.899  20.119  1   56.59  ? 295 HIS C N   1 
ATOM   6923 C CA  . HIS C 1 299 ? -38.747 33.123  20.209  1   69.12  ? 295 HIS C CA  1 
ATOM   6924 C C   . HIS C 1 299 ? -37.759 32.996  21.377  1   69.5   ? 295 HIS C C   1 
ATOM   6925 O O   . HIS C 1 299 ? -38.084 33.347  22.513  1   69.93  ? 295 HIS C O   1 
ATOM   6926 C CB  . HIS C 1 299 ? -39.697 34.321  20.375  1   80.71  ? 295 HIS C CB  1 
ATOM   6927 C CG  . HIS C 1 299 ? -40.751 34.034  21.414  1   104.25 ? 295 HIS C CG  1 
ATOM   6928 N ND1 . HIS C 1 299 ? -40.704 34.456  22.73   1   111.41 ? 295 HIS C ND1 1 
ATOM   6929 C CD2 . HIS C 1 299 ? -41.875 33.296  21.313  1   104.64 ? 295 HIS C CD2 1 
ATOM   6930 C CE1 . HIS C 1 299 ? -41.766 33.994  23.388  1   103.43 ? 295 HIS C CE1 1 
ATOM   6931 N NE2 . HIS C 1 299 ? -42.488 33.285  22.545  1   104.96 ? 295 HIS C NE2 1 
ATOM   6932 N N   . LEU C 1 300 ? -36.554 32.481  21.102  1   65.56  ? 296 LEU C N   1 
ATOM   6933 C CA  . LEU C 1 300 ? -35.559 32.261  22.143  1   65.24  ? 296 LEU C CA  1 
ATOM   6934 C C   . LEU C 1 300 ? -34.387 33.241  21.948  1   65.45  ? 296 LEU C C   1 
ATOM   6935 O O   . LEU C 1 300 ? -33.421 33.136  22.739  1   65.98  ? 296 LEU C O   1 
ATOM   6936 C CB  . LEU C 1 300 ? -35.09  30.804  22.167  1   64.59  ? 296 LEU C CB  1 
ATOM   6937 C CG  . LEU C 1 300 ? -36.192 29.743  22.053  1   66.18  ? 296 LEU C CG  1 
ATOM   6938 C CD1 . LEU C 1 300 ? -35.634 28.376  21.674  1   60.86  ? 296 LEU C CD1 1 
ATOM   6939 C CD2 . LEU C 1 300 ? -36.987 29.644  23.344  1   65.12  ? 296 LEU C CD2 1 
ATOM   6940 N N   . GLY D 2 1   ? -65.367 2.514   29.991  1   33.06  ? 171 GLY D N   1 
ATOM   6941 C CA  . GLY D 2 1   ? -64.404 2.128   31.033  1   33.83  ? 171 GLY D CA  1 
ATOM   6942 C C   . GLY D 2 1   ? -63     2.505   30.598  1   34.1   ? 171 GLY D C   1 
ATOM   6943 O O   . GLY D 2 1   ? -62.347 1.713   29.914  1   36.01  ? 171 GLY D O   1 
ATOM   6944 N N   . VAL D 2 2   ? -62.576 3.715   31.006  1   34.97  ? 172 VAL D N   1 
ATOM   6945 C CA  . VAL D 2 2   ? -61.226 4.196   30.764  1   32.51  ? 172 VAL D CA  1 
ATOM   6946 C C   . VAL D 2 2   ? -60.238 3.175   31.326  1   33.75  ? 172 VAL D C   1 
ATOM   6947 O O   . VAL D 2 2   ? -59.166 2.982   30.755  1   31.89  ? 172 VAL D O   1 
ATOM   6948 C CB  . VAL D 2 2   ? -60.93  5.61    31.285  1   30.6   ? 172 VAL D CB  1 
ATOM   6949 C CG1 . VAL D 2 2   ? -60.866 5.665   32.811  1   29.31  ? 172 VAL D CG1 1 
ATOM   6950 C CG2 . VAL D 2 2   ? -59.658 6.164   30.651  1   27.71  ? 172 VAL D CG2 1 
ATOM   6951 N N   . ASN D 2 3   ? -60.657 2.491   32.403  1   33.9   ? 173 ASN D N   1 
ATOM   6952 C CA  . ASN D 2 3   ? -59.914 1.392   33.006  1   34.56  ? 173 ASN D CA  1 
ATOM   6953 C C   . ASN D 2 3   ? -59.625 0.28    31.993  1   32.23  ? 173 ASN D C   1 
ATOM   6954 O O   . ASN D 2 3   ? -58.649 -0.453  32.139  1   31.4   ? 173 ASN D O   1 
ATOM   6955 C CB  . ASN D 2 3   ? -60.605 0.916   34.278  1   35.87  ? 173 ASN D CB  1 
ATOM   6956 C CG  . ASN D 2 3   ? -60.554 1.971   35.358  1   37.65  ? 173 ASN D CG  1 
ATOM   6957 O OD1 . ASN D 2 3   ? -59.805 2.95    35.24   1   39.68  ? 173 ASN D OD1 1 
ATOM   6958 N ND2 . ASN D 2 3   ? -61.335 1.801   36.414  1   37.39  ? 173 ASN D ND2 1 
ATOM   6959 N N   . GLU D 2 4   ? -60.465 0.177   30.957  1   32.88  ? 174 GLU D N   1 
ATOM   6960 C CA  . GLU D 2 4   ? -60.307 -0.819  29.904  1   33.92  ? 174 GLU D CA  1 
ATOM   6961 C C   . GLU D 2 4   ? -59.802 -0.167  28.619  1   31.46  ? 174 GLU D C   1 
ATOM   6962 O O   . GLU D 2 4   ? -59.779 -0.812  27.577  1   29.62  ? 174 GLU D O   1 
ATOM   6963 C CB  . GLU D 2 4   ? -61.634 -1.53   29.639  1   36.11  ? 174 GLU D CB  1 
ATOM   6964 C CG  . GLU D 2 4   ? -62.249 -2.122  30.902  1   39.33  ? 174 GLU D CG  1 
ATOM   6965 C CD  . GLU D 2 4   ? -63.51  -2.931  30.658  1   45.46  ? 174 GLU D CD  1 
ATOM   6966 O OE1 . GLU D 2 4   ? -64.123 -2.762  29.57   1   44.35  ? 174 GLU D OE1 1 
ATOM   6967 O OE2 . GLU D 2 4   ? -63.858 -3.753  31.546  1   47.04  ? 174 GLU D OE2 1 
ATOM   6968 N N   . VAL D 2 5   ? -59.4   1.112   28.715  1   31.1   ? 175 VAL D N   1 
ATOM   6969 C CA  . VAL D 2 5   ? -58.665 1.858   27.696  1   29.07  ? 175 VAL D CA  1 
ATOM   6970 C C   . VAL D 2 5   ? -59.277 1.604   26.318  1   29.23  ? 175 VAL D C   1 
ATOM   6971 O O   . VAL D 2 5   ? -58.604 1.09    25.429  1   29.24  ? 175 VAL D O   1 
ATOM   6972 C CB  . VAL D 2 5   ? -57.123 1.689   27.713  1   28.16  ? 175 VAL D CB  1 
ATOM   6973 C CG1 . VAL D 2 5   ? -56.486 2.247   28.984  1   26.31  ? 175 VAL D CG1 1 
ATOM   6974 C CG2 . VAL D 2 5   ? -56.663 0.253   27.469  1   26.41  ? 175 VAL D CG2 1 
ATOM   6975 N N   . PRO D 2 6   ? -60.579 1.93    26.117  1   31.17  ? 176 PRO D N   1 
ATOM   6976 C CA  . PRO D 2 6   ? -61.253 1.739   24.833  1   30.47  ? 176 PRO D CA  1 
ATOM   6977 C C   . PRO D 2 6   ? -60.503 2.227   23.598  1   32.03  ? 176 PRO D C   1 
ATOM   6978 O O   . PRO D 2 6   ? -60.512 1.574   22.561  1   37.26  ? 176 PRO D O   1 
ATOM   6979 C CB  . PRO D 2 6   ? -62.596 2.485   24.964  1   30.02  ? 176 PRO D CB  1 
ATOM   6980 C CG  . PRO D 2 6   ? -62.636 3.046   26.368  1   29.58  ? 176 PRO D CG  1 
ATOM   6981 C CD  . PRO D 2 6   ? -61.496 2.446   27.146  1   31.65  ? 176 PRO D CD  1 
ATOM   6982 N N   . ASP D 2 7   ? -59.906 3.412   23.686  1   30.04  ? 177 ASP D N   1 
ATOM   6983 C CA  . ASP D 2 7   ? -59.305 4.005   22.511  1   27.52  ? 177 ASP D CA  1 
ATOM   6984 C C   . ASP D 2 7   ? -57.935 3.405   22.233  1   26.79  ? 177 ASP D C   1 
ATOM   6985 O O   . ASP D 2 7   ? -57.301 3.861   21.285  1   27.82  ? 177 ASP D O   1 
ATOM   6986 C CB  . ASP D 2 7   ? -59.184 5.512   22.65   1   29.46  ? 177 ASP D CB  1 
ATOM   6987 C CG  . ASP D 2 7   ? -60.488 6.278   22.514  1   32.69  ? 177 ASP D CG  1 
ATOM   6988 O OD1 . ASP D 2 7   ? -61.241 5.954   21.569  1   35.69  ? 177 ASP D OD1 1 
ATOM   6989 O OD2 . ASP D 2 7   ? -60.733 7.191   23.341  1   32.52  ? 177 ASP D OD2 1 
ATOM   6990 N N   . TYR D 2 8   ? -57.498 2.409   23.036  1   24.62  ? 178 TYR D N   1 
ATOM   6991 C CA  . TYR D 2 8   ? -56.131 1.895   22.991  1   25.06  ? 178 TYR D CA  1 
ATOM   6992 C C   . TYR D 2 8   ? -56.036 0.364   22.955  1   28.65  ? 178 TYR D C   1 
ATOM   6993 O O   . TYR D 2 8   ? -55.026 -0.162  22.488  1   30.39  ? 178 TYR D O   1 
ATOM   6994 C CB  . TYR D 2 8   ? -55.255 2.495   24.101  1   22.69  ? 178 TYR D CB  1 
ATOM   6995 C CG  . TYR D 2 8   ? -55.091 3.997   23.946  1   20.89  ? 178 TYR D CG  1 
ATOM   6996 C CD1 . TYR D 2 8   ? -54.332 4.528   22.912  1   19.59  ? 178 TYR D CD1 1 
ATOM   6997 C CD2 . TYR D 2 8   ? -55.748 4.881   24.8    1   21.45  ? 178 TYR D CD2 1 
ATOM   6998 C CE1 . TYR D 2 8   ? -54.195 5.901   22.762  1   20.86  ? 178 TYR D CE1 1 
ATOM   6999 C CE2 . TYR D 2 8   ? -55.64  6.253   24.641  1   20.49  ? 178 TYR D CE2 1 
ATOM   7000 C CZ  . TYR D 2 8   ? -54.866 6.77    23.615  1   22.04  ? 178 TYR D CZ  1 
ATOM   7001 O OH  . TYR D 2 8   ? -54.775 8.14    23.466  1   23.93  ? 178 TYR D OH  1 
ATOM   7002 N N   . HIS D 2 9   ? -57.056 -0.365  23.437  1   33.95  ? 179 HIS D N   1 
ATOM   7003 C CA  . HIS D 2 9   ? -56.964 -1.82   23.591  1   38.64  ? 179 HIS D CA  1 
ATOM   7004 C C   . HIS D 2 9   ? -56.427 -2.489  22.32   1   37.79  ? 179 HIS D C   1 
ATOM   7005 O O   . HIS D 2 9   ? -55.641 -3.428  22.409  1   34.99  ? 179 HIS D O   1 
ATOM   7006 C CB  . HIS D 2 9   ? -58.235 -2.464  24.179  1   40.89  ? 179 HIS D CB  1 
ATOM   7007 C CG  . HIS D 2 9   ? -59.35  -2.683  23.199  1   50.35  ? 179 HIS D CG  1 
ATOM   7008 N ND1 . HIS D 2 9   ? -60.474 -1.883  23.16   1   57.8   ? 179 HIS D ND1 1 
ATOM   7009 C CD2 . HIS D 2 9   ? -59.53  -3.608  22.232  1   52.37  ? 179 HIS D CD2 1 
ATOM   7010 C CE1 . HIS D 2 9   ? -61.291 -2.306  22.195  1   56.59  ? 179 HIS D CE1 1 
ATOM   7011 N NE2 . HIS D 2 9   ? -60.73  -3.346  21.612  1   53.05  ? 179 HIS D NE2 1 
ATOM   7012 N N   . GLU D 2 10  ? -56.831 -1.991  21.142  1   40.19  ? 180 GLU D N   1 
ATOM   7013 C CA  . GLU D 2 10  ? -56.444 -2.616  19.888  1   41.69  ? 180 GLU D CA  1 
ATOM   7014 C C   . GLU D 2 10  ? -54.958 -2.373  19.62   1   39.07  ? 180 GLU D C   1 
ATOM   7015 O O   . GLU D 2 10  ? -54.204 -3.326  19.392  1   39.05  ? 180 GLU D O   1 
ATOM   7016 C CB  . GLU D 2 10  ? -57.367 -2.208  18.737  1   52.22  ? 180 GLU D CB  1 
ATOM   7017 C CG  . GLU D 2 10  ? -58.772 -2.812  18.807  1   70.04  ? 180 GLU D CG  1 
ATOM   7018 C CD  . GLU D 2 10  ? -58.933 -4.328  18.65   1   80.02  ? 180 GLU D CD  1 
ATOM   7019 O OE1 . GLU D 2 10  ? -57.92  -5.068  18.57   1   87.83  ? 180 GLU D OE1 1 
ATOM   7020 O OE2 . GLU D 2 10  ? -60.096 -4.791  18.603  1   69.82  ? 180 GLU D OE2 1 
ATOM   7021 N N   . ASP D 2 11  ? -54.554 -1.094  19.652  1   34.29  ? 181 ASP D N   1 
ATOM   7022 C CA  . ASP D 2 11  ? -53.167 -0.724  19.436  1   33.06  ? 181 ASP D CA  1 
ATOM   7023 C C   . ASP D 2 11  ? -52.282 -1.448  20.449  1   34.51  ? 181 ASP D C   1 
ATOM   7024 O O   . ASP D 2 11  ? -51.206 -1.898  20.073  1   41.11  ? 181 ASP D O   1 
ATOM   7025 C CB  . ASP D 2 11  ? -52.947 0.781   19.47   1   34.91  ? 181 ASP D CB  1 
ATOM   7026 C CG  . ASP D 2 11  ? -53.505 1.594   18.307  1   35.34  ? 181 ASP D CG  1 
ATOM   7027 O OD1 . ASP D 2 11  ? -53.989 0.971   17.335  1   35.26  ? 181 ASP D OD1 1 
ATOM   7028 O OD2 . ASP D 2 11  ? -53.461 2.85    18.389  1   32.79  ? 181 ASP D OD2 1 
ATOM   7029 N N   . ILE D 2 12  ? -52.734 -1.573  21.712  1   30.1   ? 182 ILE D N   1 
ATOM   7030 C CA  . ILE D 2 12  ? -51.95  -2.222  22.759  1   31.02  ? 182 ILE D CA  1 
ATOM   7031 C C   . ILE D 2 12  ? -51.782 -3.702  22.44   1   31.23  ? 182 ILE D C   1 
ATOM   7032 O O   . ILE D 2 12  ? -50.661 -4.199  22.481  1   33.78  ? 182 ILE D O   1 
ATOM   7033 C CB  . ILE D 2 12  ? -52.525 -2.011  24.176  1   31.08  ? 182 ILE D CB  1 
ATOM   7034 C CG1 . ILE D 2 12  ? -52.307 -0.572  24.669  1   29.57  ? 182 ILE D CG1 1 
ATOM   7035 C CG2 . ILE D 2 12  ? -51.906 -3.014  25.152  1   28.92  ? 182 ILE D CG2 1 
ATOM   7036 C CD1 . ILE D 2 12  ? -53.261 -0.13   25.767  1   29.3   ? 182 ILE D CD1 1 
ATOM   7037 N N   . HIS D 2 13  ? -52.895 -4.382  22.109  1   30.61  ? 183 HIS D N   1 
ATOM   7038 C CA  . HIS D 2 13  ? -52.903 -5.803  21.771  1   27.68  ? 183 HIS D CA  1 
ATOM   7039 C C   . HIS D 2 13  ? -51.957 -6.076  20.599  1   27.93  ? 183 HIS D C   1 
ATOM   7040 O O   . HIS D 2 13  ? -51.078 -6.946  20.688  1   30.12  ? 183 HIS D O   1 
ATOM   7041 C CB  . HIS D 2 13  ? -54.325 -6.306  21.484  1   27.99  ? 183 HIS D CB  1 
ATOM   7042 C CG  . HIS D 2 13  ? -54.331 -7.725  21.026  1   30.35  ? 183 HIS D CG  1 
ATOM   7043 N ND1 . HIS D 2 13  ? -54.283 -8.769  21.925  1   35.1   ? 183 HIS D ND1 1 
ATOM   7044 C CD2 . HIS D 2 13  ? -54.322 -8.283  19.809  1   29.15  ? 183 HIS D CD2 1 
ATOM   7045 C CE1 . HIS D 2 13  ? -54.234 -9.919  21.267  1   32.46  ? 183 HIS D CE1 1 
ATOM   7046 N NE2 . HIS D 2 13  ? -54.254 -9.638  19.984  1   31.35  ? 183 HIS D NE2 1 
ATOM   7047 N N   . THR D 2 14  ? -52.139 -5.308  19.512  1   23.63  ? 184 THR D N   1 
ATOM   7048 C CA  . THR D 2 14  ? -51.301 -5.418  18.332  1   24.74  ? 184 THR D CA  1 
ATOM   7049 C C   . THR D 2 14  ? -49.82  -5.306  18.719  1   29.49  ? 184 THR D C   1 
ATOM   7050 O O   . THR D 2 14  ? -49.006 -6.094  18.263  1   30.63  ? 184 THR D O   1 
ATOM   7051 C CB  . THR D 2 14  ? -51.727 -4.379  17.295  1   23.54  ? 184 THR D CB  1 
ATOM   7052 O OG1 . THR D 2 14  ? -53.031 -4.738  16.825  1   25.17  ? 184 THR D OG1 1 
ATOM   7053 C CG2 . THR D 2 14  ? -50.773 -4.337  16.115  1   19.94  ? 184 THR D CG2 1 
ATOM   7054 N N   . TYR D 2 15  ? -49.481 -4.323  19.566  1   31.09  ? 185 TYR D N   1 
ATOM   7055 C CA  . TYR D 2 15  ? -48.12  -4.077  20.017  1   30.73  ? 185 TYR D CA  1 
ATOM   7056 C C   . TYR D 2 15  ? -47.617 -5.238  20.873  1   28.94  ? 185 TYR D C   1 
ATOM   7057 O O   . TYR D 2 15  ? -46.479 -5.653  20.714  1   28.36  ? 185 TYR D O   1 
ATOM   7058 C CB  . TYR D 2 15  ? -48.02  -2.757  20.788  1   30.35  ? 185 TYR D CB  1 
ATOM   7059 C CG  . TYR D 2 15  ? -46.624 -2.443  21.291  1   30.98  ? 185 TYR D CG  1 
ATOM   7060 C CD1 . TYR D 2 15  ? -45.608 -2.145  20.385  1   32.26  ? 185 TYR D CD1 1 
ATOM   7061 C CD2 . TYR D 2 15  ? -46.325 -2.427  22.652  1   30.34  ? 185 TYR D CD2 1 
ATOM   7062 C CE1 . TYR D 2 15  ? -44.326 -1.844  20.808  1   33.65  ? 185 TYR D CE1 1 
ATOM   7063 C CE2 . TYR D 2 15  ? -45.043 -2.128  23.093  1   30.96  ? 185 TYR D CE2 1 
ATOM   7064 C CZ  . TYR D 2 15  ? -44.045 -1.843  22.165  1   36.32  ? 185 TYR D CZ  1 
ATOM   7065 O OH  . TYR D 2 15  ? -42.751 -1.558  22.499  1   37.92  ? 185 TYR D OH  1 
ATOM   7066 N N   . LEU D 2 16  ? -48.457 -5.743  21.786  1   28.49  ? 186 LEU D N   1 
ATOM   7067 C CA  . LEU D 2 16  ? -48.045 -6.827  22.671  1   26.05  ? 186 LEU D CA  1 
ATOM   7068 C C   . LEU D 2 16  ? -47.696 -8.054  21.829  1   26.34  ? 186 LEU D C   1 
ATOM   7069 O O   . LEU D 2 16  ? -46.788 -8.789  22.163  1   24.26  ? 186 LEU D O   1 
ATOM   7070 C CB  . LEU D 2 16  ? -49.126 -7.153  23.707  1   24.2   ? 186 LEU D CB  1 
ATOM   7071 C CG  . LEU D 2 16  ? -49.372 -6.125  24.813  1   24.09  ? 186 LEU D CG  1 
ATOM   7072 C CD1 . LEU D 2 16  ? -50.583 -6.49   25.642  1   22.31  ? 186 LEU D CD1 1 
ATOM   7073 C CD2 . LEU D 2 16  ? -48.127 -5.977  25.687  1   23.9   ? 186 LEU D CD2 1 
ATOM   7074 N N   . ARG D 2 17  ? -48.442 -8.291  20.74   1   29.92  ? 187 ARG D N   1 
ATOM   7075 C CA  . ARG D 2 17  ? -48.212 -9.446  19.883  1   30.63  ? 187 ARG D CA  1 
ATOM   7076 C C   . ARG D 2 17  ? -46.83  -9.34   19.242  1   31.8   ? 187 ARG D C   1 
ATOM   7077 O O   . ARG D 2 17  ? -46.097 -10.323 19.132  1   32.61  ? 187 ARG D O   1 
ATOM   7078 C CB  . ARG D 2 17  ? -49.291 -9.571  18.797  1   26.98  ? 187 ARG D CB  1 
ATOM   7079 C CG  . ARG D 2 17  ? -50.641 -10.061 19.302  1   26     ? 187 ARG D CG  1 
ATOM   7080 C CD  . ARG D 2 17  ? -50.556 -11.531 19.681  1   24.9   ? 187 ARG D CD  1 
ATOM   7081 N NE  . ARG D 2 17  ? -50.448 -12.342 18.469  1   24.79  ? 187 ARG D NE  1 
ATOM   7082 C CZ  . ARG D 2 17  ? -51.497 -12.763 17.757  1   23.82  ? 187 ARG D CZ  1 
ATOM   7083 N NH1 . ARG D 2 17  ? -52.735 -12.624 18.24   1   24.65  ? 187 ARG D NH1 1 
ATOM   7084 N NH2 . ARG D 2 17  ? -51.283 -13.388 16.613  1   20.11  ? 187 ARG D NH2 1 
ATOM   7085 N N   . GLU D 2 18  ? -46.504 -8.125  18.804  1   30.9   ? 188 GLU D N   1 
ATOM   7086 C CA  . GLU D 2 18  ? -45.214 -7.833  18.208  1   34.55  ? 188 GLU D CA  1 
ATOM   7087 C C   . GLU D 2 18  ? -44.095 -8.075  19.226  1   32.8   ? 188 GLU D C   1 
ATOM   7088 O O   . GLU D 2 18  ? -43.086 -8.686  18.885  1   32.16  ? 188 GLU D O   1 
ATOM   7089 C CB  . GLU D 2 18  ? -45.327 -6.37   17.806  1   37.7   ? 188 GLU D CB  1 
ATOM   7090 C CG  . GLU D 2 18  ? -44.588 -5.98   16.535  1   43.34  ? 188 GLU D CG  1 
ATOM   7091 C CD  . GLU D 2 18  ? -44.71  -4.467  16.419  1   45.11  ? 188 GLU D CD  1 
ATOM   7092 O OE1 . GLU D 2 18  ? -45.851 -4.013  16.124  1   39.52  ? 188 GLU D OE1 1 
ATOM   7093 O OE2 . GLU D 2 18  ? -43.681 -3.771  16.672  1   38.56  ? 188 GLU D OE2 1 
ATOM   7094 N N   . MET D 2 19  ? -44.3   -7.641  20.475  1   28.9   ? 189 MET D N   1 
ATOM   7095 C CA  . MET D 2 19  ? -43.253 -7.623  21.476  1   30.37  ? 189 MET D CA  1 
ATOM   7096 C C   . MET D 2 19  ? -42.976 -9.023  22.017  1   32.61  ? 189 MET D C   1 
ATOM   7097 O O   . MET D 2 19  ? -41.838 -9.339  22.381  1   34.36  ? 189 MET D O   1 
ATOM   7098 C CB  . MET D 2 19  ? -43.627 -6.698  22.637  1   32.52  ? 189 MET D CB  1 
ATOM   7099 C CG  . MET D 2 19  ? -43.505 -5.229  22.307  1   37.03  ? 189 MET D CG  1 
ATOM   7100 S SD  . MET D 2 19  ? -41.902 -4.747  21.623  1   41.67  ? 189 MET D SD  1 
ATOM   7101 C CE  . MET D 2 19  ? -40.812 -5.174  22.999  1   51.12  ? 189 MET D CE  1 
ATOM   7102 N N   . GLU D 2 20  ? -44.018 -9.854  22.104  1   31.25  ? 190 GLU D N   1 
ATOM   7103 C CA  . GLU D 2 20  ? -43.856 -11.204 22.622  1   32.26  ? 190 GLU D CA  1 
ATOM   7104 C C   . GLU D 2 20  ? -42.984 -12.054 21.685  1   33.24  ? 190 GLU D C   1 
ATOM   7105 O O   . GLU D 2 20  ? -42.382 -13.037 22.098  1   39.16  ? 190 GLU D O   1 
ATOM   7106 C CB  . GLU D 2 20  ? -45.219 -11.857 22.834  1   30.33  ? 190 GLU D CB  1 
ATOM   7107 C CG  . GLU D 2 20  ? -45.835 -12.324 21.523  1   28.97  ? 190 GLU D CG  1 
ATOM   7108 C CD  . GLU D 2 20  ? -47.165 -13.025 21.685  1   31.31  ? 190 GLU D CD  1 
ATOM   7109 O OE1 . GLU D 2 20  ? -47.464 -13.479 22.817  1   28.13  ? 190 GLU D OE1 1 
ATOM   7110 O OE2 . GLU D 2 20  ? -47.883 -13.125 20.649  1   32.11  ? 190 GLU D OE2 1 
ATOM   7111 N N   . VAL D 2 21  ? -42.938 -11.7   20.405  1   32.05  ? 191 VAL D N   1 
ATOM   7112 C CA  . VAL D 2 21  ? -42.076 -12.367 19.447  1   31.7   ? 191 VAL D CA  1 
ATOM   7113 C C   . VAL D 2 21  ? -40.648 -11.956 19.763  1   35.93  ? 191 VAL D C   1 
ATOM   7114 O O   . VAL D 2 21  ? -39.771 -12.81  19.798  1   40.06  ? 191 VAL D O   1 
ATOM   7115 C CB  . VAL D 2 21  ? -42.435 -12.024 17.983  1   30.06  ? 191 VAL D CB  1 
ATOM   7116 C CG1 . VAL D 2 21  ? -41.384 -12.489 16.97   1   26.28  ? 191 VAL D CG1 1 
ATOM   7117 C CG2 . VAL D 2 21  ? -43.82  -12.531 17.611  1   27.11  ? 191 VAL D CG2 1 
ATOM   7118 N N   . LYS D 2 22  ? -40.442 -10.653 19.99   1   37.7   ? 192 LYS D N   1 
ATOM   7119 C CA  . LYS D 2 22  ? -39.118 -10.123 20.26   1   43.84  ? 192 LYS D CA  1 
ATOM   7120 C C   . LYS D 2 22  ? -38.577 -10.622 21.598  1   37.86  ? 192 LYS D C   1 
ATOM   7121 O O   . LYS D 2 22  ? -37.372 -10.805 21.74   1   39.96  ? 192 LYS D O   1 
ATOM   7122 C CB  . LYS D 2 22  ? -39.072 -8.599  20.097  1   61.41  ? 192 LYS D CB  1 
ATOM   7123 C CG  . LYS D 2 22  ? -38.557 -8.111  18.727  1   78.88  ? 192 LYS D CG  1 
ATOM   7124 C CD  . LYS D 2 22  ? -37.746 -6.814  18.837  1   91.7   ? 192 LYS D CD  1 
ATOM   7125 C CE  . LYS D 2 22  ? -36.418 -6.762  18.108  1   89.98  ? 192 LYS D CE  1 
ATOM   7126 N NZ  . LYS D 2 22  ? -36.539 -6.791  16.649  1   88.25  ? 192 LYS D NZ  1 
ATOM   7127 N N   . CYS D 2 23  ? -39.461 -10.847 22.569  1   37.08  ? 193 CYS D N   1 
ATOM   7128 C CA  . CYS D 2 23  ? -39.024 -11.247 23.902  1   40.54  ? 193 CYS D CA  1 
ATOM   7129 C C   . CYS D 2 23  ? -38.992 -12.761 24.059  1   39.1   ? 193 CYS D C   1 
ATOM   7130 O O   . CYS D 2 23  ? -38.696 -13.244 25.147  1   41.16  ? 193 CYS D O   1 
ATOM   7131 C CB  . CYS D 2 23  ? -39.966 -10.77  25.004  1   39.89  ? 193 CYS D CB  1 
ATOM   7132 S SG  . CYS D 2 23  ? -39.827 -8.997  25.335  1   42.43  ? 193 CYS D SG  1 
ATOM   7133 N N   . LYS D 2 24  ? -39.32  -13.494 22.991  1   40.59  ? 194 LYS D N   1 
ATOM   7134 C CA  . LYS D 2 24  ? -39.434 -14.938 23.087  1   42.8   ? 194 LYS D CA  1 
ATOM   7135 C C   . LYS D 2 24  ? -38.058 -15.54  23.373  1   39.95  ? 194 LYS D C   1 
ATOM   7136 O O   . LYS D 2 24  ? -37.083 -15.151 22.742  1   37.94  ? 194 LYS D O   1 
ATOM   7137 C CB  . LYS D 2 24  ? -40.01  -15.531 21.797  1   42.68  ? 194 LYS D CB  1 
ATOM   7138 C CG  . LYS D 2 24  ? -40.466 -16.981 21.938  1   41.25  ? 194 LYS D CG  1 
ATOM   7139 C CD  . LYS D 2 24  ? -40.875 -17.563 20.593  1   44.9   ? 194 LYS D CD  1 
ATOM   7140 C CE  . LYS D 2 24  ? -41.38  -18.979 20.656  1   50.41  ? 194 LYS D CE  1 
ATOM   7141 N NZ  . LYS D 2 24  ? -42.007 -19.327 19.373  1   50.63  ? 194 LYS D NZ  1 
ATOM   7142 N N   . PRO D 2 25  ? -37.951 -16.489 24.336  1   38.77  ? 195 PRO D N   1 
ATOM   7143 C CA  . PRO D 2 25  ? -36.723 -17.263 24.544  1   37.49  ? 195 PRO D CA  1 
ATOM   7144 C C   . PRO D 2 25  ? -36.432 -18.199 23.38   1   37.79  ? 195 PRO D C   1 
ATOM   7145 O O   . PRO D 2 25  ? -37.312 -18.446 22.57   1   43.1   ? 195 PRO D O   1 
ATOM   7146 C CB  . PRO D 2 25  ? -36.998 -18.088 25.807  1   38.69  ? 195 PRO D CB  1 
ATOM   7147 C CG  . PRO D 2 25  ? -38.238 -17.464 26.423  1   39.85  ? 195 PRO D CG  1 
ATOM   7148 C CD  . PRO D 2 25  ? -39.022 -16.851 25.286  1   38.76  ? 195 PRO D CD  1 
ATOM   7149 N N   . LYS D 2 26  ? -35.217 -18.756 23.348  1   38.31  ? 196 LYS D N   1 
ATOM   7150 C CA  . LYS D 2 26  ? -34.852 -19.777 22.383  1   38.08  ? 196 LYS D CA  1 
ATOM   7151 C C   . LYS D 2 26  ? -35.531 -21.098 22.741  1   39.46  ? 196 LYS D C   1 
ATOM   7152 O O   . LYS D 2 26  ? -35.286 -21.646 23.815  1   38.72  ? 196 LYS D O   1 
ATOM   7153 C CB  . LYS D 2 26  ? -33.333 -19.976 22.327  1   42.86  ? 196 LYS D CB  1 
ATOM   7154 C CG  . LYS D 2 26  ? -32.562 -19.258 21.227  1   54.22  ? 196 LYS D CG  1 
ATOM   7155 C CD  . LYS D 2 26  ? -32.404 -17.748 21.378  1   70.95  ? 196 LYS D CD  1 
ATOM   7156 C CE  . LYS D 2 26  ? -31.24  -17.254 20.579  1   78.32  ? 196 LYS D CE  1 
ATOM   7157 N NZ  . LYS D 2 26  ? -30.004 -17.858 21.087  1   79.75  ? 196 LYS D NZ  1 
ATOM   7158 N N   . VAL D 2 27  ? -36.308 -21.639 21.788  1   42.25  ? 197 VAL D N   1 
ATOM   7159 C CA  . VAL D 2 27  ? -37.147 -22.813 21.972  1   40.87  ? 197 VAL D CA  1 
ATOM   7160 C C   . VAL D 2 27  ? -36.345 -24.022 22.457  1   39.77  ? 197 VAL D C   1 
ATOM   7161 O O   . VAL D 2 27  ? -36.856 -24.791 23.268  1   45.91  ? 197 VAL D O   1 
ATOM   7162 C CB  . VAL D 2 27  ? -38.003 -23.148 20.735  1   43.4   ? 197 VAL D CB  1 
ATOM   7163 C CG1 . VAL D 2 27  ? -38.703 -24.498 20.86   1   43.76  ? 197 VAL D CG1 1 
ATOM   7164 C CG2 . VAL D 2 27  ? -39.035 -22.057 20.464  1   46.19  ? 197 VAL D CG2 1 
ATOM   7165 N N   . GLY D 2 28  ? -35.116 -24.22  21.966  1   34.31  ? 198 GLY D N   1 
ATOM   7166 C CA  . GLY D 2 28  ? -34.409 -25.423 22.378  1   35.02  ? 198 GLY D CA  1 
ATOM   7167 C C   . GLY D 2 28  ? -33.152 -25.152 23.203  1   40.27  ? 198 GLY D C   1 
ATOM   7168 O O   . GLY D 2 28  ? -32.156 -25.862 23.024  1   43.44  ? 198 GLY D O   1 
ATOM   7169 N N   . TYR D 2 29  ? -33.218 -24.153 24.105  1   36.23  ? 199 TYR D N   1 
ATOM   7170 C CA  . TYR D 2 29  ? -32.024 -23.645 24.776  1   34.13  ? 199 TYR D CA  1 
ATOM   7171 C C   . TYR D 2 29  ? -31.494 -24.692 25.756  1   32.41  ? 199 TYR D C   1 
ATOM   7172 O O   . TYR D 2 29  ? -30.297 -24.768 25.984  1   30.61  ? 199 TYR D O   1 
ATOM   7173 C CB  . TYR D 2 29  ? -32.181 -22.258 25.428  1   30.73  ? 199 TYR D CB  1 
ATOM   7174 C CG  . TYR D 2 29  ? -32.898 -22.208 26.775  1   27.48  ? 199 TYR D CG  1 
ATOM   7175 C CD1 . TYR D 2 29  ? -32.281 -22.677 27.93   1   27.17  ? 199 TYR D CD1 1 
ATOM   7176 C CD2 . TYR D 2 29  ? -34.186 -21.69  26.903  1   26.98  ? 199 TYR D CD2 1 
ATOM   7177 C CE1 . TYR D 2 29  ? -32.914 -22.629 29.168  1   27.79  ? 199 TYR D CE1 1 
ATOM   7178 C CE2 . TYR D 2 29  ? -34.836 -21.655 28.131  1   27.21  ? 199 TYR D CE2 1 
ATOM   7179 C CZ  . TYR D 2 29  ? -34.192 -22.105 29.274  1   26.98  ? 199 TYR D CZ  1 
ATOM   7180 O OH  . TYR D 2 29  ? -34.804 -22.074 30.493  1   26.56  ? 199 TYR D OH  1 
ATOM   7181 N N   . MET D 2 30  ? -32.388 -25.497 26.335  1   34.31  ? 200 MET D N   1 
ATOM   7182 C CA  . MET D 2 30  ? -32.009 -26.364 27.44   1   35.89  ? 200 MET D CA  1 
ATOM   7183 C C   . MET D 2 30  ? -31.002 -27.419 26.968  1   37.29  ? 200 MET D C   1 
ATOM   7184 O O   . MET D 2 30  ? -30.064 -27.767 27.684  1   35.07  ? 200 MET D O   1 
ATOM   7185 C CB  . MET D 2 30  ? -33.253 -26.951 28.125  1   34.79  ? 200 MET D CB  1 
ATOM   7186 C CG  . MET D 2 30  ? -32.978 -27.476 29.511  1   35.43  ? 200 MET D CG  1 
ATOM   7187 S SD  . MET D 2 30  ? -32.223 -26.196 30.528  1   43.43  ? 200 MET D SD  1 
ATOM   7188 C CE  . MET D 2 30  ? -33.715 -25.494 31.24   1   44.36  ? 200 MET D CE  1 
ATOM   7189 N N   . LYS D 2 31  ? -31.178 -27.911 25.737  1   39.23  ? 201 LYS D N   1 
ATOM   7190 C CA  . LYS D 2 31  ? -30.276 -28.914 25.19   1   40.43  ? 201 LYS D CA  1 
ATOM   7191 C C   . LYS D 2 31  ? -28.881 -28.311 25.015  1   37.24  ? 201 LYS D C   1 
ATOM   7192 O O   . LYS D 2 31  ? -27.895 -29.039 25.042  1   38.8   ? 201 LYS D O   1 
ATOM   7193 C CB  . LYS D 2 31  ? -30.722 -29.464 23.826  1   44.42  ? 201 LYS D CB  1 
ATOM   7194 C CG  . LYS D 2 31  ? -31.982 -30.314 23.785  1   51.43  ? 201 LYS D CG  1 
ATOM   7195 C CD  . LYS D 2 31  ? -32.229 -30.804 22.357  1   54.03  ? 201 LYS D CD  1 
ATOM   7196 C CE  . LYS D 2 31  ? -32.606 -29.768 21.327  1   53.69  ? 201 LYS D CE  1 
ATOM   7197 N NZ  . LYS D 2 31  ? -33.875 -29.07  21.575  1   50.62  ? 201 LYS D NZ  1 
ATOM   7198 N N   . LYS D 2 32  ? -28.795 -26.987 24.839  1   36.21  ? 202 LYS D N   1 
ATOM   7199 C CA  . LYS D 2 32  ? -27.52  -26.307 24.654  1   39.08  ? 202 LYS D CA  1 
ATOM   7200 C C   . LYS D 2 32  ? -26.915 -25.908 26.001  1   35.87  ? 202 LYS D C   1 
ATOM   7201 O O   . LYS D 2 32  ? -25.775 -25.451 26.025  1   36.34  ? 202 LYS D O   1 
ATOM   7202 C CB  . LYS D 2 32  ? -27.658 -25.038 23.805  1   46.93  ? 202 LYS D CB  1 
ATOM   7203 C CG  . LYS D 2 32  ? -28.036 -25.255 22.339  1   57.67  ? 202 LYS D CG  1 
ATOM   7204 C CD  . LYS D 2 32  ? -28.208 -24.022 21.462  1   66.33  ? 202 LYS D CD  1 
ATOM   7205 C CE  . LYS D 2 32  ? -28.554 -24.387 20.045  1   68.92  ? 202 LYS D CE  1 
ATOM   7206 N NZ  . LYS D 2 32  ? -28.754 -23.234 19.16   1   62.56  ? 202 LYS D NZ  1 
ATOM   7207 N N   . GLN D 2 33  ? -27.686 -26.04  27.097  1   32.38  ? 203 GLN D N   1 
ATOM   7208 C CA  . GLN D 2 33  ? -27.179 -25.872 28.458  1   29.11  ? 203 GLN D CA  1 
ATOM   7209 C C   . GLN D 2 33  ? -26.507 -27.169 28.918  1   32.01  ? 203 GLN D C   1 
ATOM   7210 O O   . GLN D 2 33  ? -27.174 -28.16  29.234  1   30.19  ? 203 GLN D O   1 
ATOM   7211 C CB  . GLN D 2 33  ? -28.272 -25.468 29.446  1   25.24  ? 203 GLN D CB  1 
ATOM   7212 C CG  . GLN D 2 33  ? -28.757 -24.036 29.29   1   24.96  ? 203 GLN D CG  1 
ATOM   7213 C CD  . GLN D 2 33  ? -27.766 -23.014 29.807  1   25.53  ? 203 GLN D CD  1 
ATOM   7214 O OE1 . GLN D 2 33  ? -26.771 -23.333 30.468  1   24.13  ? 203 GLN D OE1 1 
ATOM   7215 N NE2 . GLN D 2 33  ? -28.04  -21.755 29.509  1   25.48  ? 203 GLN D NE2 1 
ATOM   7216 N N   . PRO D 2 34  ? -25.153 -27.215 28.983  1   32.89  ? 204 PRO D N   1 
ATOM   7217 C CA  . PRO D 2 34  ? -24.462 -28.453 29.34   1   31.09  ? 204 PRO D CA  1 
ATOM   7218 C C   . PRO D 2 34  ? -24.776 -29.01  30.726  1   29.99  ? 204 PRO D C   1 
ATOM   7219 O O   . PRO D 2 34  ? -24.659 -30.205 30.952  1   33.06  ? 204 PRO D O   1 
ATOM   7220 C CB  . PRO D 2 34  ? -22.977 -28.094 29.163  1   31.8   ? 204 PRO D CB  1 
ATOM   7221 C CG  . PRO D 2 34  ? -22.927 -26.586 29.344  1   35.16  ? 204 PRO D CG  1 
ATOM   7222 C CD  . PRO D 2 34  ? -24.226 -26.094 28.743  1   33.2   ? 204 PRO D CD  1 
ATOM   7223 N N   . ASP D 2 35  ? -25.213 -28.158 31.651  1   32.81  ? 205 ASP D N   1 
ATOM   7224 C CA  . ASP D 2 35  ? -25.239 -28.576 33.04   1   35.28  ? 205 ASP D CA  1 
ATOM   7225 C C   . ASP D 2 35  ? -26.6   -28.346 33.699  1   35.94  ? 205 ASP D C   1 
ATOM   7226 O O   . ASP D 2 35  ? -26.742 -28.591 34.899  1   40.75  ? 205 ASP D O   1 
ATOM   7227 C CB  . ASP D 2 35  ? -24.079 -27.981 33.82   1   37.77  ? 205 ASP D CB  1 
ATOM   7228 C CG  . ASP D 2 35  ? -23.927 -28.534 35.229  1   42.47  ? 205 ASP D CG  1 
ATOM   7229 O OD1 . ASP D 2 35  ? -23.862 -29.776 35.359  1   48.32  ? 205 ASP D OD1 1 
ATOM   7230 O OD2 . ASP D 2 35  ? -23.899 -27.724 36.188  1   42.7   ? 205 ASP D OD2 1 
ATOM   7231 N N   . ILE D 2 36  ? -27.605 -27.893 32.941  1   31.59  ? 206 ILE D N   1 
ATOM   7232 C CA  . ILE D 2 36  ? -28.915 -27.691 33.547  1   32.08  ? 206 ILE D CA  1 
ATOM   7233 C C   . ILE D 2 36  ? -30.004 -28.267 32.635  1   31.37  ? 206 ILE D C   1 
ATOM   7234 O O   . ILE D 2 36  ? -29.81  -28.407 31.434  1   28.85  ? 206 ILE D O   1 
ATOM   7235 C CB  . ILE D 2 36  ? -29.143 -26.225 33.996  1   37.06  ? 206 ILE D CB  1 
ATOM   7236 C CG1 . ILE D 2 36  ? -29.017 -25.227 32.864  1   37.44  ? 206 ILE D CG1 1 
ATOM   7237 C CG2 . ILE D 2 36  ? -28.235 -25.811 35.167  1   35.16  ? 206 ILE D CG2 1 
ATOM   7238 C CD1 . ILE D 2 36  ? -29.176 -23.798 33.337  1   39.43  ? 206 ILE D CD1 1 
ATOM   7239 N N   . THR D 2 37  ? -31.147 -28.641 33.229  1   34.14  ? 207 THR D N   1 
ATOM   7240 C CA  . THR D 2 37  ? -32.146 -29.496 32.597  1   34.37  ? 207 THR D CA  1 
ATOM   7241 C C   . THR D 2 37  ? -33.535 -28.896 32.77   1   33.53  ? 207 THR D C   1 
ATOM   7242 O O   . THR D 2 37  ? -33.73  -28     33.578  1   33.77  ? 207 THR D O   1 
ATOM   7243 C CB  . THR D 2 37  ? -32.138 -30.902 33.202  1   35.82  ? 207 THR D CB  1 
ATOM   7244 O OG1 . THR D 2 37  ? -32.483 -30.781 34.581  1   41.9   ? 207 THR D OG1 1 
ATOM   7245 C CG2 . THR D 2 37  ? -30.839 -31.656 32.982  1   32.44  ? 207 THR D CG2 1 
ATOM   7246 N N   . ASN D 2 38  ? -34.508 -29.444 32.039  1   34.21  ? 208 ASN D N   1 
ATOM   7247 C CA  . ASN D 2 38  ? -35.88  -28.985 32.144  1   36.07  ? 208 ASN D CA  1 
ATOM   7248 C C   . ASN D 2 38  ? -36.378 -29.165 33.578  1   37.99  ? 208 ASN D C   1 
ATOM   7249 O O   . ASN D 2 38  ? -37.127 -28.326 34.08   1   36.64  ? 208 ASN D O   1 
ATOM   7250 C CB  . ASN D 2 38  ? -36.774 -29.688 31.129  1   39.81  ? 208 ASN D CB  1 
ATOM   7251 C CG  . ASN D 2 38  ? -36.54  -29.212 29.715  1   40.66  ? 208 ASN D CG  1 
ATOM   7252 O OD1 . ASN D 2 38  ? -36.259 -28.031 29.482  1   42.48  ? 208 ASN D OD1 1 
ATOM   7253 N ND2 . ASN D 2 38  ? -36.664 -30.116 28.757  1   37.29  ? 208 ASN D ND2 1 
ATOM   7254 N N   . SER D 2 39  ? -35.92  -30.254 34.22   1   41.32  ? 209 SER D N   1 
ATOM   7255 C CA  . SER D 2 39  ? -36.275 -30.667 35.576  1   38.85  ? 209 SER D CA  1 
ATOM   7256 C C   . SER D 2 39  ? -35.796 -29.653 36.617  1   35.76  ? 209 SER D C   1 
ATOM   7257 O O   . SER D 2 39  ? -36.534 -29.313 37.541  1   37.78  ? 209 SER D O   1 
ATOM   7258 C CB  . SER D 2 39  ? -35.717 -32.039 35.89   1   39.99  ? 209 SER D CB  1 
ATOM   7259 O OG  . SER D 2 39  ? -35.722 -32.29  37.289  1   41.9   ? 209 SER D OG  1 
ATOM   7260 N N   . MET D 2 40  ? -34.539 -29.223 36.486  1   29.54  ? 210 MET D N   1 
ATOM   7261 C CA  . MET D 2 40  ? -33.964 -28.23  37.379  1   28.43  ? 210 MET D CA  1 
ATOM   7262 C C   . MET D 2 40  ? -34.733 -26.921 37.267  1   28.01  ? 210 MET D C   1 
ATOM   7263 O O   . MET D 2 40  ? -34.979 -26.266 38.275  1   29.39  ? 210 MET D O   1 
ATOM   7264 C CB  . MET D 2 40  ? -32.504 -27.943 37.025  1   25.91  ? 210 MET D CB  1 
ATOM   7265 C CG  . MET D 2 40  ? -31.612 -29.066 37.416  1   26.05  ? 210 MET D CG  1 
ATOM   7266 S SD  . MET D 2 40  ? -29.942 -28.695 36.878  1   24.84  ? 210 MET D SD  1 
ATOM   7267 C CE  . MET D 2 40  ? -29.316 -30.376 36.768  1   20.74  ? 210 MET D CE  1 
ATOM   7268 N N   . ARG D 2 41  ? -35.093 -26.57  36.029  1   26.17  ? 211 ARG D N   1 
ATOM   7269 C CA  . ARG D 2 41  ? -35.78  -25.331 35.734  1   28     ? 211 ARG D CA  1 
ATOM   7270 C C   . ARG D 2 41  ? -37.148 -25.35  36.408  1   28.56  ? 211 ARG D C   1 
ATOM   7271 O O   . ARG D 2 41  ? -37.547 -24.336 37.001  1   29.17  ? 211 ARG D O   1 
ATOM   7272 C CB  . ARG D 2 41  ? -35.901 -25.137 34.218  1   28.72  ? 211 ARG D CB  1 
ATOM   7273 C CG  . ARG D 2 41  ? -36.553 -23.823 33.812  1   27.95  ? 211 ARG D CG  1 
ATOM   7274 C CD  . ARG D 2 41  ? -36.888 -23.823 32.344  1   30.88  ? 211 ARG D CD  1 
ATOM   7275 N NE  . ARG D 2 41  ? -37.783 -22.728 31.965  1   31.61  ? 211 ARG D NE  1 
ATOM   7276 C CZ  . ARG D 2 41  ? -39.07  -22.676 32.28   1   29.43  ? 211 ARG D CZ  1 
ATOM   7277 N NH1 . ARG D 2 41  ? -39.614 -23.644 32.992  1   26.65  ? 211 ARG D NH1 1 
ATOM   7278 N NH2 . ARG D 2 41  ? -39.798 -21.641 31.892  1   26.9   ? 211 ARG D NH2 1 
ATOM   7279 N N   . ALA D 2 42  ? -37.845 -26.495 36.264  1   28.61  ? 212 ALA D N   1 
ATOM   7280 C CA  . ALA D 2 42  ? -39.124 -26.756 36.911  1   28.97  ? 212 ALA D CA  1 
ATOM   7281 C C   . ALA D 2 42  ? -38.994 -26.53  38.42   1   29.39  ? 212 ALA D C   1 
ATOM   7282 O O   . ALA D 2 42  ? -39.849 -25.887 39.035  1   31.03  ? 212 ALA D O   1 
ATOM   7283 C CB  . ALA D 2 42  ? -39.623 -28.145 36.575  1   24.3   ? 212 ALA D CB  1 
ATOM   7284 N N   . ILE D 2 43  ? -37.9   -27.025 39.011  1   27.92  ? 213 ILE D N   1 
ATOM   7285 C CA  . ILE D 2 43  ? -37.7   -26.881 40.44   1   27.69  ? 213 ILE D CA  1 
ATOM   7286 C C   . ILE D 2 43  ? -37.568 -25.397 40.786  1   29.34  ? 213 ILE D C   1 
ATOM   7287 O O   . ILE D 2 43  ? -38.156 -24.928 41.767  1   30.19  ? 213 ILE D O   1 
ATOM   7288 C CB  . ILE D 2 43  ? -36.497 -27.722 40.879  1   28.85  ? 213 ILE D CB  1 
ATOM   7289 C CG1 . ILE D 2 43  ? -36.829 -29.219 40.824  1   25.62  ? 213 ILE D CG1 1 
ATOM   7290 C CG2 . ILE D 2 43  ? -36.004 -27.29  42.263  1   28.33  ? 213 ILE D CG2 1 
ATOM   7291 C CD1 . ILE D 2 43  ? -35.606 -30.112 40.946  1   26.12  ? 213 ILE D CD1 1 
ATOM   7292 N N   . LEU D 2 44  ? -36.836 -24.675 39.931  1   27.17  ? 214 LEU D N   1 
ATOM   7293 C CA  . LEU D 2 44  ? -36.61  -23.252 40.085  1   26.45  ? 214 LEU D CA  1 
ATOM   7294 C C   . LEU D 2 44  ? -37.936 -22.498 40.03   1   26.54  ? 214 LEU D C   1 
ATOM   7295 O O   . LEU D 2 44  ? -38.27  -21.788 40.978  1   28.02  ? 214 LEU D O   1 
ATOM   7296 C CB  . LEU D 2 44  ? -35.635 -22.749 39.026  1   25.16  ? 214 LEU D CB  1 
ATOM   7297 C CG  . LEU D 2 44  ? -35.259 -21.269 39.141  1   25.11  ? 214 LEU D CG  1 
ATOM   7298 C CD1 . LEU D 2 44  ? -34.603 -20.995 40.462  1   22.8   ? 214 LEU D CD1 1 
ATOM   7299 C CD2 . LEU D 2 44  ? -34.365 -20.832 37.985  1   26.02  ? 214 LEU D CD2 1 
ATOM   7300 N N   . VAL D 2 45  ? -38.67  -22.644 38.918  1   25.56  ? 215 VAL D N   1 
ATOM   7301 C CA  . VAL D 2 45  ? -39.915 -21.912 38.726  1   26.04  ? 215 VAL D CA  1 
ATOM   7302 C C   . VAL D 2 45  ? -40.859 -22.241 39.892  1   28.64  ? 215 VAL D C   1 
ATOM   7303 O O   . VAL D 2 45  ? -41.56  -21.35  40.389  1   26.88  ? 215 VAL D O   1 
ATOM   7304 C CB  . VAL D 2 45  ? -40.588 -22.147 37.355  1   23.78  ? 215 VAL D CB  1 
ATOM   7305 C CG1 . VAL D 2 45  ? -41.967 -21.497 37.251  1   23.24  ? 215 VAL D CG1 1 
ATOM   7306 C CG2 . VAL D 2 45  ? -39.725 -21.658 36.21   1   22.69  ? 215 VAL D CG2 1 
ATOM   7307 N N   . ASP D 2 46  ? -40.847 -23.512 40.336  1   26.01  ? 216 ASP D N   1 
ATOM   7308 C CA  . ASP D 2 46  ? -41.774 -23.935 41.367  1   27.62  ? 216 ASP D CA  1 
ATOM   7309 C C   . ASP D 2 46  ? -41.475 -23.197 42.666  1   28.65  ? 216 ASP D C   1 
ATOM   7310 O O   . ASP D 2 46  ? -42.398 -22.783 43.368  1   31.7   ? 216 ASP D O   1 
ATOM   7311 C CB  . ASP D 2 46  ? -41.702 -25.42  41.652  1   28.2   ? 216 ASP D CB  1 
ATOM   7312 C CG  . ASP D 2 46  ? -42.791 -25.884 42.606  1   28.7   ? 216 ASP D CG  1 
ATOM   7313 O OD1 . ASP D 2 46  ? -43.945 -26.018 42.152  1   28.2   ? 216 ASP D OD1 1 
ATOM   7314 O OD2 . ASP D 2 46  ? -42.492 -26.026 43.804  1   28.64  ? 216 ASP D OD2 1 
ATOM   7315 N N   . TRP D 2 47  ? -40.178 -23.066 42.965  1   26.41  ? 217 TRP D N   1 
ATOM   7316 C CA  . TRP D 2 47  ? -39.679 -22.296 44.091  1   28.14  ? 217 TRP D CA  1 
ATOM   7317 C C   . TRP D 2 47  ? -40.118 -20.823 44.014  1   28.71  ? 217 TRP D C   1 
ATOM   7318 O O   . TRP D 2 47  ? -40.601 -20.287 45.012  1   29.4   ? 217 TRP D O   1 
ATOM   7319 C CB  . TRP D 2 47  ? -38.154 -22.472 44.215  1   25.97  ? 217 TRP D CB  1 
ATOM   7320 C CG  . TRP D 2 47  ? -37.522 -21.583 45.252  1   27.36  ? 217 TRP D CG  1 
ATOM   7321 C CD1 . TRP D 2 47  ? -37.637 -21.689 46.606  1   27.67  ? 217 TRP D CD1 1 
ATOM   7322 C CD2 . TRP D 2 47  ? -36.674 -20.434 45.012  1   27.83  ? 217 TRP D CD2 1 
ATOM   7323 N NE1 . TRP D 2 47  ? -36.915 -20.698 47.226  1   28.19  ? 217 TRP D NE1 1 
ATOM   7324 C CE2 . TRP D 2 47  ? -36.31  -19.917 46.279  1   28.08  ? 217 TRP D CE2 1 
ATOM   7325 C CE3 . TRP D 2 47  ? -36.182 -19.811 43.863  1   25.04  ? 217 TRP D CE3 1 
ATOM   7326 C CZ2 . TRP D 2 47  ? -35.495 -18.8   46.431  1   26.63  ? 217 TRP D CZ2 1 
ATOM   7327 C CZ3 . TRP D 2 47  ? -35.392 -18.696 44.017  1   27.67  ? 217 TRP D CZ3 1 
ATOM   7328 C CH2 . TRP D 2 47  ? -35.046 -18.202 45.279  1   26.94  ? 217 TRP D CH2 1 
ATOM   7329 N N   . LEU D 2 48  ? -39.948 -20.184 42.842  1   26.94  ? 218 LEU D N   1 
ATOM   7330 C CA  . LEU D 2 48  ? -40.376 -18.813 42.598  1   27.92  ? 218 LEU D CA  1 
ATOM   7331 C C   . LEU D 2 48  ? -41.865 -18.618 42.905  1   30.07  ? 218 LEU D C   1 
ATOM   7332 O O   . LEU D 2 48  ? -42.249 -17.587 43.454  1   30.32  ? 218 LEU D O   1 
ATOM   7333 C CB  . LEU D 2 48  ? -40.01  -18.366 41.182  1   25.57  ? 218 LEU D CB  1 
ATOM   7334 C CG  . LEU D 2 48  ? -38.507 -18.183 40.929  1   28.69  ? 218 LEU D CG  1 
ATOM   7335 C CD1 . LEU D 2 48  ? -38.214 -17.687 39.526  1   25.99  ? 218 LEU D CD1 1 
ATOM   7336 C CD2 . LEU D 2 48  ? -37.838 -17.265 41.949  1   26.16  ? 218 LEU D CD2 1 
ATOM   7337 N N   . VAL D 2 49  ? -42.702 -19.606 42.558  1   31.5   ? 219 VAL D N   1 
ATOM   7338 C CA  . VAL D 2 49  ? -44.121 -19.579 42.894  1   33.45  ? 219 VAL D CA  1 
ATOM   7339 C C   . VAL D 2 49  ? -44.317 -19.446 44.412  1   33.26  ? 219 VAL D C   1 
ATOM   7340 O O   . VAL D 2 49  ? -45.101 -18.608 44.84   1   34.08  ? 219 VAL D O   1 
ATOM   7341 C CB  . VAL D 2 49  ? -44.874 -20.802 42.33   1   33.74  ? 219 VAL D CB  1 
ATOM   7342 C CG1 . VAL D 2 49  ? -46.263 -20.974 42.957  1   30.34  ? 219 VAL D CG1 1 
ATOM   7343 C CG2 . VAL D 2 49  ? -44.942 -20.769 40.805  1   31.34  ? 219 VAL D CG2 1 
ATOM   7344 N N   . GLU D 2 50  ? -43.624 -20.272 45.217  1   30.11  ? 220 GLU D N   1 
ATOM   7345 C CA  . GLU D 2 50  ? -43.664 -20.157 46.67   1   32.2   ? 220 GLU D CA  1 
ATOM   7346 C C   . GLU D 2 50  ? -43.236 -18.764 47.134  1   32.7   ? 220 GLU D C   1 
ATOM   7347 O O   . GLU D 2 50  ? -43.92  -18.143 47.943  1   30.33  ? 220 GLU D O   1 
ATOM   7348 C CB  . GLU D 2 50  ? -42.669 -21.077 47.372  1   38.22  ? 220 GLU D CB  1 
ATOM   7349 C CG  . GLU D 2 50  ? -43.124 -22.524 47.554  1   44.22  ? 220 GLU D CG  1 
ATOM   7350 C CD  . GLU D 2 50  ? -42.043 -23.41  48.162  1   50.61  ? 220 GLU D CD  1 
ATOM   7351 O OE1 . GLU D 2 50  ? -42.395 -24.523 48.626  1   59.71  ? 220 GLU D OE1 1 
ATOM   7352 O OE2 . GLU D 2 50  ? -40.85  -23.012 48.144  1   54.33  ? 220 GLU D OE2 1 
ATOM   7353 N N   . VAL D 2 51  ? -42.079 -18.298 46.643  1   31.37  ? 221 VAL D N   1 
ATOM   7354 C CA  . VAL D 2 51  ? -41.57  -16.984 47      1   30.34  ? 221 VAL D CA  1 
ATOM   7355 C C   . VAL D 2 51  ? -42.626 -15.927 46.694  1   29.74  ? 221 VAL D C   1 
ATOM   7356 O O   . VAL D 2 51  ? -42.851 -15.024 47.51   1   28.12  ? 221 VAL D O   1 
ATOM   7357 C CB  . VAL D 2 51  ? -40.238 -16.671 46.297  1   28.51  ? 221 VAL D CB  1 
ATOM   7358 C CG1 . VAL D 2 51  ? -39.84  -15.2   46.451  1   22.31  ? 221 VAL D CG1 1 
ATOM   7359 C CG2 . VAL D 2 51  ? -39.15  -17.623 46.783  1   27.8   ? 221 VAL D CG2 1 
ATOM   7360 N N   . GLY D 2 52  ? -43.274 -16.084 45.527  1   27.33  ? 222 GLY D N   1 
ATOM   7361 C CA  . GLY D 2 52  ? -44.389 -15.238 45.13   1   28.48  ? 222 GLY D CA  1 
ATOM   7362 C C   . GLY D 2 52  ? -45.499 -15.212 46.187  1   31.4   ? 222 GLY D C   1 
ATOM   7363 O O   . GLY D 2 52  ? -46.051 -14.147 46.478  1   32.24  ? 222 GLY D O   1 
ATOM   7364 N N   . GLU D 2 53  ? -45.8   -16.388 46.755  1   33.04  ? 223 GLU D N   1 
ATOM   7365 C CA  . GLU D 2 53  ? -46.827 -16.585 47.775  1   34.05  ? 223 GLU D CA  1 
ATOM   7366 C C   . GLU D 2 53  ? -46.377 -15.978 49.102  1   30.91  ? 223 GLU D C   1 
ATOM   7367 O O   . GLU D 2 53  ? -47.073 -15.141 49.656  1   30.36  ? 223 GLU D O   1 
ATOM   7368 C CB  . GLU D 2 53  ? -47.128 -18.083 47.902  1   35.33  ? 223 GLU D CB  1 
ATOM   7369 C CG  . GLU D 2 53  ? -47.749 -18.707 46.656  1   41.7   ? 223 GLU D CG  1 
ATOM   7370 C CD  . GLU D 2 53  ? -49.053 -18.05  46.229  1   49.6   ? 223 GLU D CD  1 
ATOM   7371 O OE1 . GLU D 2 53  ? -49.886 -17.7   47.111  1   48.26  ? 223 GLU D OE1 1 
ATOM   7372 O OE2 . GLU D 2 53  ? -49.232 -17.896 44.995  1   54.13  ? 223 GLU D OE2 1 
ATOM   7373 N N   . GLU D 2 54  ? -45.19  -16.38  49.572  1   32.47  ? 224 GLU D N   1 
ATOM   7374 C CA  . GLU D 2 54  ? -44.57  -15.911 50.803  1   32.93  ? 224 GLU D CA  1 
ATOM   7375 C C   . GLU D 2 54  ? -44.51  -14.38  50.914  1   31.7   ? 224 GLU D C   1 
ATOM   7376 O O   . GLU D 2 54  ? -44.612 -13.842 52.006  1   34.8   ? 224 GLU D O   1 
ATOM   7377 C CB  . GLU D 2 54  ? -43.171 -16.521 50.847  1   38.24  ? 224 GLU D CB  1 
ATOM   7378 C CG  . GLU D 2 54  ? -42.247 -15.897 51.889  1   44.17  ? 224 GLU D CG  1 
ATOM   7379 C CD  . GLU D 2 54  ? -42.38  -16.447 53.291  1   56.47  ? 224 GLU D CD  1 
ATOM   7380 O OE1 . GLU D 2 54  ? -43.52  -16.577 53.804  1   61.36  ? 224 GLU D OE1 1 
ATOM   7381 O OE2 . GLU D 2 54  ? -41.312 -16.729 53.873  1   65.85  ? 224 GLU D OE2 1 
ATOM   7382 N N   . TYR D 2 55  ? -44.316 -13.667 49.804  1   31.1   ? 225 TYR D N   1 
ATOM   7383 C CA  . TYR D 2 55  ? -44.114 -12.226 49.834  1   32.27  ? 225 TYR D CA  1 
ATOM   7384 C C   . TYR D 2 55  ? -45.296 -11.489 49.204  1   33.22  ? 225 TYR D C   1 
ATOM   7385 O O   . TYR D 2 55  ? -45.241 -10.274 49.034  1   35.09  ? 225 TYR D O   1 
ATOM   7386 C CB  . TYR D 2 55  ? -42.782 -11.871 49.162  1   33.41  ? 225 TYR D CB  1 
ATOM   7387 C CG  . TYR D 2 55  ? -41.579 -12.214 50.031  1   35.59  ? 225 TYR D CG  1 
ATOM   7388 C CD1 . TYR D 2 55  ? -41.153 -11.344 51.031  1   32.41  ? 225 TYR D CD1 1 
ATOM   7389 C CD2 . TYR D 2 55  ? -40.892 -13.416 49.885  1   35.92  ? 225 TYR D CD2 1 
ATOM   7390 C CE1 . TYR D 2 55  ? -40.079 -11.652 51.851  1   31.4   ? 225 TYR D CE1 1 
ATOM   7391 C CE2 . TYR D 2 55  ? -39.812 -13.731 50.701  1   34.56  ? 225 TYR D CE2 1 
ATOM   7392 C CZ  . TYR D 2 55  ? -39.411 -12.851 51.693  1   32.25  ? 225 TYR D CZ  1 
ATOM   7393 O OH  . TYR D 2 55  ? -38.337 -13.093 52.499  1   32.69  ? 225 TYR D OH  1 
ATOM   7394 N N   . LYS D 2 56  ? -46.355 -12.243 48.875  1   36.86  ? 226 LYS D N   1 
ATOM   7395 C CA  . LYS D 2 56  ? -47.62  -11.748 48.341  1   35.36  ? 226 LYS D CA  1 
ATOM   7396 C C   . LYS D 2 56  ? -47.364 -10.899 47.097  1   31.84  ? 226 LYS D C   1 
ATOM   7397 O O   . LYS D 2 56  ? -47.923 -9.813  46.941  1   30.99  ? 226 LYS D O   1 
ATOM   7398 C CB  . LYS D 2 56  ? -48.381 -10.959 49.41   1   38     ? 226 LYS D CB  1 
ATOM   7399 C CG  . LYS D 2 56  ? -48.39  -11.517 50.827  1   39.77  ? 226 LYS D CG  1 
ATOM   7400 C CD  . LYS D 2 56  ? -49.548 -12.462 51.13   1   44.39  ? 226 LYS D CD  1 
ATOM   7401 C CE  . LYS D 2 56  ? -49.974 -12.326 52.572  1   38.86  ? 226 LYS D CE  1 
ATOM   7402 N NZ  . LYS D 2 56  ? -51.32  -12.861 52.765  1   38.05  ? 226 LYS D NZ  1 
ATOM   7403 N N   . LEU D 2 57  ? -46.512 -11.421 46.211  1   28.89  ? 227 LEU D N   1 
ATOM   7404 C CA  . LEU D 2 57  ? -46.174 -10.733 44.978  1   30.1   ? 227 LEU D CA  1 
ATOM   7405 C C   . LEU D 2 57  ? -47.317 -10.923 43.987  1   31.17  ? 227 LEU D C   1 
ATOM   7406 O O   . LEU D 2 57  ? -48.052 -11.898 44.1    1   32.06  ? 227 LEU D O   1 
ATOM   7407 C CB  . LEU D 2 57  ? -44.879 -11.317 44.411  1   28.11  ? 227 LEU D CB  1 
ATOM   7408 C CG  . LEU D 2 57  ? -43.659 -11.258 45.333  1   25.64  ? 227 LEU D CG  1 
ATOM   7409 C CD1 . LEU D 2 57  ? -42.44  -11.823 44.603  1   23.45  ? 227 LEU D CD1 1 
ATOM   7410 C CD2 . LEU D 2 57  ? -43.437 -9.843  45.863  1   22.1   ? 227 LEU D CD2 1 
ATOM   7411 N N   . GLN D 2 58  ? -47.409 -10.027 42.988  1   31.7   ? 228 GLN D N   1 
ATOM   7412 C CA  . GLN D 2 58  ? -48.359 -10.159 41.893  1   31.77  ? 228 GLN D CA  1 
ATOM   7413 C C   . GLN D 2 58  ? -47.97  -11.364 41.032  1   33.86  ? 228 GLN D C   1 
ATOM   7414 O O   . GLN D 2 58  ? -46.787 -11.651 40.846  1   35.34  ? 228 GLN D O   1 
ATOM   7415 C CB  . GLN D 2 58  ? -48.351 -8.894  41.036  1   29.85  ? 228 GLN D CB  1 
ATOM   7416 C CG  . GLN D 2 58  ? -48.772 -7.648  41.799  1   30.32  ? 228 GLN D CG  1 
ATOM   7417 C CD  . GLN D 2 58  ? -50.237 -7.73   42.168  1   31.99  ? 228 GLN D CD  1 
ATOM   7418 O OE1 . GLN D 2 58  ? -51.111 -7.687  41.3    1   33.59  ? 228 GLN D OE1 1 
ATOM   7419 N NE2 . GLN D 2 58  ? -50.518 -7.908  43.448  1   27.71  ? 228 GLN D NE2 1 
ATOM   7420 N N   . ASN D 2 59  ? -48.978 -12.058 40.5    1   30.42  ? 229 ASN D N   1 
ATOM   7421 C CA  . ASN D 2 59  ? -48.751 -13.143 39.565  1   28.51  ? 229 ASN D CA  1 
ATOM   7422 C C   . ASN D 2 59  ? -47.953 -12.661 38.352  1   27.39  ? 229 ASN D C   1 
ATOM   7423 O O   . ASN D 2 59  ? -47.171 -13.442 37.804  1   26.74  ? 229 ASN D O   1 
ATOM   7424 C CB  . ASN D 2 59  ? -50.067 -13.782 39.143  1   26.74  ? 229 ASN D CB  1 
ATOM   7425 C CG  . ASN D 2 59  ? -50.744 -14.488 40.291  1   28.26  ? 229 ASN D CG  1 
ATOM   7426 O OD1 . ASN D 2 59  ? -50.085 -14.926 41.245  1   28.42  ? 229 ASN D OD1 1 
ATOM   7427 N ND2 . ASN D 2 59  ? -52.054 -14.639 40.193  1   25.18  ? 229 ASN D ND2 1 
ATOM   7428 N N   . GLU D 2 60  ? -48.186 -11.401 37.934  1   25.55  ? 230 GLU D N   1 
ATOM   7429 C CA  . GLU D 2 60  ? -47.476 -10.768 36.833  1   26.5   ? 230 GLU D CA  1 
ATOM   7430 C C   . GLU D 2 60  ? -45.968 -10.737 37.098  1   29.76  ? 230 GLU D C   1 
ATOM   7431 O O   . GLU D 2 60  ? -45.166 -10.841 36.159  1   31.11  ? 230 GLU D O   1 
ATOM   7432 C CB  . GLU D 2 60  ? -48.017 -9.351  36.63   1   26.53  ? 230 GLU D CB  1 
ATOM   7433 C CG  . GLU D 2 60  ? -47.331 -8.561  35.515  1   26.89  ? 230 GLU D CG  1 
ATOM   7434 C CD  . GLU D 2 60  ? -47.453 -9.099  34.104  1   27.5   ? 230 GLU D CD  1 
ATOM   7435 O OE1 . GLU D 2 60  ? -48.153 -10.104 33.933  1   30.31  ? 230 GLU D OE1 1 
ATOM   7436 O OE2 . GLU D 2 60  ? -46.869 -8.51   33.176  1   28.34  ? 230 GLU D OE2 1 
ATOM   7437 N N   . THR D 2 61  ? -45.585 -10.601 38.38   1   27.65  ? 231 THR D N   1 
ATOM   7438 C CA  . THR D 2 61  ? -44.176 -10.534 38.731  1   29.49  ? 231 THR D CA  1 
ATOM   7439 C C   . THR D 2 61  ? -43.513 -11.882 38.45   1   30.38  ? 231 THR D C   1 
ATOM   7440 O O   . THR D 2 61  ? -42.436 -11.927 37.855  1   32.44  ? 231 THR D O   1 
ATOM   7441 C CB  . THR D 2 61  ? -43.96  -10.037 40.163  1   31.35  ? 231 THR D CB  1 
ATOM   7442 O OG1 . THR D 2 61  ? -44.69  -8.814  40.291  1   30.24  ? 231 THR D OG1 1 
ATOM   7443 C CG2 . THR D 2 61  ? -42.492 -9.764  40.465  1   25.96  ? 231 THR D CG2 1 
ATOM   7444 N N   . LEU D 2 62  ? -44.189 -12.963 38.847  1   29.24  ? 232 LEU D N   1 
ATOM   7445 C CA  . LEU D 2 62  ? -43.745 -14.325 38.606  1   28.01  ? 232 LEU D CA  1 
ATOM   7446 C C   . LEU D 2 62  ? -43.577 -14.577 37.112  1   29.71  ? 232 LEU D C   1 
ATOM   7447 O O   . LEU D 2 62  ? -42.553 -15.107 36.696  1   34.28  ? 232 LEU D O   1 
ATOM   7448 C CB  . LEU D 2 62  ? -44.753 -15.281 39.238  1   26.38  ? 232 LEU D CB  1 
ATOM   7449 C CG  . LEU D 2 62  ? -44.553 -16.764 38.919  1   25.94  ? 232 LEU D CG  1 
ATOM   7450 C CD1 . LEU D 2 62  ? -43.271 -17.269 39.519  1   25.51  ? 232 LEU D CD1 1 
ATOM   7451 C CD2 . LEU D 2 62  ? -45.721 -17.582 39.422  1   26.65  ? 232 LEU D CD2 1 
ATOM   7452 N N   . HIS D 2 63  ? -44.566 -14.183 36.3    1   31.09  ? 233 HIS D N   1 
ATOM   7453 C CA  . HIS D 2 63  ? -44.495 -14.371 34.851  1   31.23  ? 233 HIS D CA  1 
ATOM   7454 C C   . HIS D 2 63  ? -43.285 -13.646 34.249  1   30.78  ? 233 HIS D C   1 
ATOM   7455 O O   . HIS D 2 63  ? -42.562 -14.214 33.434  1   36.03  ? 233 HIS D O   1 
ATOM   7456 C CB  . HIS D 2 63  ? -45.816 -13.977 34.164  1   30.64  ? 233 HIS D CB  1 
ATOM   7457 C CG  . HIS D 2 63  ? -46.887 -15.002 34.178  1   28.23  ? 233 HIS D CG  1 
ATOM   7458 N ND1 . HIS D 2 63  ? -47.706 -15.183 35.279  1   28.86  ? 233 HIS D ND1 1 
ATOM   7459 C CD2 . HIS D 2 63  ? -47.266 -15.894 33.264  1   25.92  ? 233 HIS D CD2 1 
ATOM   7460 C CE1 . HIS D 2 63  ? -48.559 -16.165 35.034  1   26.58  ? 233 HIS D CE1 1 
ATOM   7461 N NE2 . HIS D 2 63  ? -48.306 -16.612 33.824  1   27.73  ? 233 HIS D NE2 1 
ATOM   7462 N N   . LEU D 2 64  ? -43.089 -12.375 34.629  1   30.38  ? 234 LEU D N   1 
ATOM   7463 C CA  . LEU D 2 64  ? -41.944 -11.592 34.194  1   28.61  ? 234 LEU D CA  1 
ATOM   7464 C C   . LEU D 2 64  ? -40.636 -12.276 34.602  1   32.16  ? 234 LEU D C   1 
ATOM   7465 O O   . LEU D 2 64  ? -39.699 -12.376 33.788  1   35.86  ? 234 LEU D O   1 
ATOM   7466 C CB  . LEU D 2 64  ? -42.026 -10.196 34.791  1   25.73  ? 234 LEU D CB  1 
ATOM   7467 C CG  . LEU D 2 64  ? -43.088 -9.268  34.2    1   29.6   ? 234 LEU D CG  1 
ATOM   7468 C CD1 . LEU D 2 64  ? -43.291 -8.061  35.12   1   31.74  ? 234 LEU D CD1 1 
ATOM   7469 C CD2 . LEU D 2 64  ? -42.729 -8.788  32.805  1   25.81  ? 234 LEU D CD2 1 
ATOM   7470 N N   . ALA D 2 65  ? -40.558 -12.734 35.863  1   29.24  ? 235 ALA D N   1 
ATOM   7471 C CA  . ALA D 2 65  ? -39.321 -13.344 36.345  1   30.93  ? 235 ALA D CA  1 
ATOM   7472 C C   . ALA D 2 65  ? -38.958 -14.558 35.487  1   30.39  ? 235 ALA D C   1 
ATOM   7473 O O   . ALA D 2 65  ? -37.795 -14.724 35.124  1   29.4   ? 235 ALA D O   1 
ATOM   7474 C CB  . ALA D 2 65  ? -39.406 -13.686 37.82   1   29.61  ? 235 ALA D CB  1 
ATOM   7475 N N   . VAL D 2 66  ? -39.967 -15.367 35.136  1   27.7   ? 236 VAL D N   1 
ATOM   7476 C CA  . VAL D 2 66  ? -39.733 -16.546 34.327  1   28.9   ? 236 VAL D CA  1 
ATOM   7477 C C   . VAL D 2 66  ? -39.237 -16.125 32.936  1   31.96  ? 236 VAL D C   1 
ATOM   7478 O O   . VAL D 2 66  ? -38.281 -16.697 32.399  1   32.2   ? 236 VAL D O   1 
ATOM   7479 C CB  . VAL D 2 66  ? -40.971 -17.463 34.269  1   30.01  ? 236 VAL D CB  1 
ATOM   7480 C CG1 . VAL D 2 66  ? -40.752 -18.597 33.273  1   28.59  ? 236 VAL D CG1 1 
ATOM   7481 C CG2 . VAL D 2 66  ? -41.378 -18.012 35.645  1   27.05  ? 236 VAL D CG2 1 
ATOM   7482 N N   . ASN D 2 67  ? -39.867 -15.098 32.353  1   29.11  ? 237 ASN D N   1 
ATOM   7483 C CA  . ASN D 2 67  ? -39.434 -14.59  31.062  1   26.87  ? 237 ASN D CA  1 
ATOM   7484 C C   . ASN D 2 67  ? -37.939 -14.227 31.101  1   30.38  ? 237 ASN D C   1 
ATOM   7485 O O   . ASN D 2 67  ? -37.166 -14.606 30.218  1   28.01  ? 237 ASN D O   1 
ATOM   7486 C CB  . ASN D 2 67  ? -40.262 -13.371 30.694  1   28.1   ? 237 ASN D CB  1 
ATOM   7487 C CG  . ASN D 2 67  ? -39.936 -12.886 29.3    1   31.17  ? 237 ASN D CG  1 
ATOM   7488 O OD1 . ASN D 2 67  ? -39.206 -11.896 29.129  1   31.35  ? 237 ASN D OD1 1 
ATOM   7489 N ND2 . ASN D 2 67  ? -40.43  -13.598 28.296  1   27.99  ? 237 ASN D ND2 1 
ATOM   7490 N N   . TYR D 2 68  ? -37.534 -13.487 32.149  1   31.24  ? 238 TYR D N   1 
ATOM   7491 C CA  . TYR D 2 68  ? -36.183 -12.968 32.3    1   29.54  ? 238 TYR D CA  1 
ATOM   7492 C C   . TYR D 2 68  ? -35.182 -14.119 32.366  1   30.88  ? 238 TYR D C   1 
ATOM   7493 O O   . TYR D 2 68  ? -34.116 -14.057 31.735  1   32.47  ? 238 TYR D O   1 
ATOM   7494 C CB  . TYR D 2 68  ? -36.012 -12.067 33.528  1   27.79  ? 238 TYR D CB  1 
ATOM   7495 C CG  . TYR D 2 68  ? -36.897 -10.827 33.566  1   26.73  ? 238 TYR D CG  1 
ATOM   7496 C CD1 . TYR D 2 68  ? -37.558 -10.374 32.431  1   25.56  ? 238 TYR D CD1 1 
ATOM   7497 C CD2 . TYR D 2 68  ? -37.093 -10.131 34.756  1   27.09  ? 238 TYR D CD2 1 
ATOM   7498 C CE1 . TYR D 2 68  ? -38.396 -9.27   32.471  1   27.01  ? 238 TYR D CE1 1 
ATOM   7499 C CE2 . TYR D 2 68  ? -37.925 -9.026  34.812  1   28.82  ? 238 TYR D CE2 1 
ATOM   7500 C CZ  . TYR D 2 68  ? -38.59  -8.608  33.668  1   28.71  ? 238 TYR D CZ  1 
ATOM   7501 O OH  . TYR D 2 68  ? -39.409 -7.518  33.687  1   30.39  ? 238 TYR D OH  1 
ATOM   7502 N N   . ILE D 2 69  ? -35.549 -15.167 33.115  1   29.41  ? 239 ILE D N   1 
ATOM   7503 C CA  . ILE D 2 69  ? -34.727 -16.359 33.273  1   28.49  ? 239 ILE D CA  1 
ATOM   7504 C C   . ILE D 2 69  ? -34.522 -17.059 31.937  1   28.84  ? 239 ILE D C   1 
ATOM   7505 O O   . ILE D 2 69  ? -33.387 -17.364 31.579  1   29.09  ? 239 ILE D O   1 
ATOM   7506 C CB  . ILE D 2 69  ? -35.332 -17.326 34.293  1   27.65  ? 239 ILE D CB  1 
ATOM   7507 C CG1 . ILE D 2 69  ? -35.298 -16.7   35.698  1   28.18  ? 239 ILE D CG1 1 
ATOM   7508 C CG2 . ILE D 2 69  ? -34.607 -18.675 34.224  1   27.69  ? 239 ILE D CG2 1 
ATOM   7509 C CD1 . ILE D 2 69  ? -36.247 -17.354 36.69   1   25.72  ? 239 ILE D CD1 1 
ATOM   7510 N N   . ASP D 2 70  ? -35.623 -17.321 31.226  1   29.25  ? 240 ASP D N   1 
ATOM   7511 C CA  . ASP D 2 70  ? -35.568 -18.074 29.98   1   29.21  ? 240 ASP D CA  1 
ATOM   7512 C C   . ASP D 2 70  ? -34.737 -17.334 28.937  1   27.11  ? 240 ASP D C   1 
ATOM   7513 O O   . ASP D 2 70  ? -33.994 -17.97  28.187  1   25.74  ? 240 ASP D O   1 
ATOM   7514 C CB  . ASP D 2 70  ? -36.953 -18.476 29.5    1   31.2   ? 240 ASP D CB  1 
ATOM   7515 C CG  . ASP D 2 70  ? -37.639 -19.548 30.34   1   31.63  ? 240 ASP D CG  1 
ATOM   7516 O OD1 . ASP D 2 70  ? -36.925 -20.474 30.822  1   29.15  ? 240 ASP D OD1 1 
ATOM   7517 O OD2 . ASP D 2 70  ? -38.88  -19.482 30.463  1   30.29  ? 240 ASP D OD2 1 
ATOM   7518 N N   . ARG D 2 71  ? -34.827 -15.993 28.925  1   25.39  ? 241 ARG D N   1 
ATOM   7519 C CA  . ARG D 2 71  ? -34.059 -15.224 27.952  1   26.78  ? 241 ARG D CA  1 
ATOM   7520 C C   . ARG D 2 71  ? -32.588 -15.22  28.357  1   29.01  ? 241 ARG D C   1 
ATOM   7521 O O   . ARG D 2 71  ? -31.704 -15.307 27.498  1   31.97  ? 241 ARG D O   1 
ATOM   7522 C CB  . ARG D 2 71  ? -34.58  -13.797 27.768  1   25.79  ? 241 ARG D CB  1 
ATOM   7523 C CG  . ARG D 2 71  ? -35.866 -13.737 26.959  1   28.77  ? 241 ARG D CG  1 
ATOM   7524 C CD  . ARG D 2 71  ? -36.762 -12.583 27.389  1   32     ? 241 ARG D CD  1 
ATOM   7525 N NE  . ARG D 2 71  ? -36.141 -11.359 26.889  1   31.59  ? 241 ARG D NE  1 
ATOM   7526 C CZ  . ARG D 2 71  ? -36.348 -10.15  27.379  1   30.27  ? 241 ARG D CZ  1 
ATOM   7527 N NH1 . ARG D 2 71  ? -37.291 -9.919  28.275  1   29.26  ? 241 ARG D NH1 1 
ATOM   7528 N NH2 . ARG D 2 71  ? -35.586 -9.176  26.947  1   28.09  ? 241 ARG D NH2 1 
ATOM   7529 N N   . PHE D 2 72  ? -32.346 -15.15  29.672  1   27.98  ? 242 PHE D N   1 
ATOM   7530 C CA  . PHE D 2 72  ? -30.986 -15.11  30.182  1   28.1   ? 242 PHE D CA  1 
ATOM   7531 C C   . PHE D 2 72  ? -30.281 -16.406 29.805  1   27.81  ? 242 PHE D C   1 
ATOM   7532 O O   . PHE D 2 72  ? -29.14  -16.377 29.341  1   28.61  ? 242 PHE D O   1 
ATOM   7533 C CB  . PHE D 2 72  ? -30.951 -14.837 31.691  1   25.26  ? 242 PHE D CB  1 
ATOM   7534 C CG  . PHE D 2 72  ? -29.538 -14.689 32.229  1   24.61  ? 242 PHE D CG  1 
ATOM   7535 C CD1 . PHE D 2 72  ? -28.826 -15.808 32.659  1   25.55  ? 242 PHE D CD1 1 
ATOM   7536 C CD2 . PHE D 2 72  ? -28.904 -13.45  32.262  1   24.21  ? 242 PHE D CD2 1 
ATOM   7537 C CE1 . PHE D 2 72  ? -27.527 -15.697 33.151  1   23.37  ? 242 PHE D CE1 1 
ATOM   7538 C CE2 . PHE D 2 72  ? -27.617 -13.341 32.785  1   26.21  ? 242 PHE D CE2 1 
ATOM   7539 C CZ  . PHE D 2 72  ? -26.928 -14.459 33.23   1   23.77  ? 242 PHE D CZ  1 
ATOM   7540 N N   . LEU D 2 73  ? -30.97  -17.533 30.03   1   28.27  ? 243 LEU D N   1 
ATOM   7541 C CA  . LEU D 2 73  ? -30.427 -18.859 29.772  1   27.87  ? 243 LEU D CA  1 
ATOM   7542 C C   . LEU D 2 73  ? -30.438 -19.176 28.276  1   26.08  ? 243 LEU D C   1 
ATOM   7543 O O   . LEU D 2 73  ? -29.866 -20.178 27.87   1   25.14  ? 243 LEU D O   1 
ATOM   7544 C CB  . LEU D 2 73  ? -31.256 -19.878 30.552  1   28.1   ? 243 LEU D CB  1 
ATOM   7545 C CG  . LEU D 2 73  ? -31.193 -19.792 32.077  1   27.79  ? 243 LEU D CG  1 
ATOM   7546 C CD1 . LEU D 2 73  ? -32.19  -20.759 32.691  1   26.54  ? 243 LEU D CD1 1 
ATOM   7547 C CD2 . LEU D 2 73  ? -29.779 -20.089 32.566  1   29.48  ? 243 LEU D CD2 1 
ATOM   7548 N N   . SER D 2 74  ? -31.098 -18.34  27.464  1   27.86  ? 244 SER D N   1 
ATOM   7549 C CA  . SER D 2 74  ? -30.995 -18.441 26.011  1   28.86  ? 244 SER D CA  1 
ATOM   7550 C C   . SER D 2 74  ? -29.637 -17.936 25.536  1   27.79  ? 244 SER D C   1 
ATOM   7551 O O   . SER D 2 74  ? -29.262 -18.189 24.396  1   27.74  ? 244 SER D O   1 
ATOM   7552 C CB  . SER D 2 74  ? -32.116 -17.702 25.308  1   30.14  ? 244 SER D CB  1 
ATOM   7553 O OG  . SER D 2 74  ? -33.389 -18.273 25.595  1   32.79  ? 244 SER D OG  1 
ATOM   7554 N N   . SER D 2 75  ? -28.895 -17.248 26.418  1   29.72  ? 245 SER D N   1 
ATOM   7555 C CA  . SER D 2 75  ? -27.713 -16.489 26.017  1   33.58  ? 245 SER D CA  1 
ATOM   7556 C C   . SER D 2 75  ? -26.493 -16.821 26.878  1   30.82  ? 245 SER D C   1 
ATOM   7557 O O   . SER D 2 75  ? -25.384 -16.551 26.457  1   31.08  ? 245 SER D O   1 
ATOM   7558 C CB  . SER D 2 75  ? -27.969 -14.986 26.027  1   38.79  ? 245 SER D CB  1 
ATOM   7559 O OG  . SER D 2 75  ? -29.356 -14.651 25.937  1   43.75  ? 245 SER D OG  1 
ATOM   7560 N N   . MET D 2 76  ? -26.675 -17.402 28.071  1   30.54  ? 246 MET D N   1 
ATOM   7561 C CA  . MET D 2 76  ? -25.568 -17.557 29.012  1   29.11  ? 246 MET D CA  1 
ATOM   7562 C C   . MET D 2 76  ? -25.524 -18.991 29.559  1   30.95  ? 246 MET D C   1 
ATOM   7563 O O   . MET D 2 76  ? -26.508 -19.508 30.091  1   35.34  ? 246 MET D O   1 
ATOM   7564 C CB  . MET D 2 76  ? -25.74  -16.582 30.184  1   27.56  ? 246 MET D CB  1 
ATOM   7565 C CG  . MET D 2 76  ? -25.793 -15.116 29.787  1   28.92  ? 246 MET D CG  1 
ATOM   7566 S SD  . MET D 2 76  ? -24.22  -14.449 29.204  1   32.42  ? 246 MET D SD  1 
ATOM   7567 C CE  . MET D 2 76  ? -23.249 -14.357 30.716  1   27.21  ? 246 MET D CE  1 
ATOM   7568 N N   . SER D 2 77  ? -24.381 -19.659 29.422  1   28.37  ? 247 SER D N   1 
ATOM   7569 C CA  . SER D 2 77  ? -24.252 -20.978 30.024  1   27.35  ? 247 SER D CA  1 
ATOM   7570 C C   . SER D 2 77  ? -24.182 -20.821 31.544  1   27.95  ? 247 SER D C   1 
ATOM   7571 O O   . SER D 2 77  ? -23.4   -20.015 32.044  1   30.42  ? 247 SER D O   1 
ATOM   7572 C CB  . SER D 2 77  ? -23.017 -21.676 29.507  1   22.74  ? 247 SER D CB  1 
ATOM   7573 O OG  . SER D 2 77  ? -23.229 -22.134 28.182  1   24.22  ? 247 SER D OG  1 
ATOM   7574 N N   . VAL D 2 78  ? -24.996 -21.589 32.269  1   26.43  ? 248 VAL D N   1 
ATOM   7575 C CA  . VAL D 2 78  ? -25.072 -21.473 33.718  1   26.66  ? 248 VAL D CA  1 
ATOM   7576 C C   . VAL D 2 78  ? -24.908 -22.851 34.362  1   28.05  ? 248 VAL D C   1 
ATOM   7577 O O   . VAL D 2 78  ? -25.584 -23.813 33.986  1   28.04  ? 248 VAL D O   1 
ATOM   7578 C CB  . VAL D 2 78  ? -26.372 -20.775 34.168  1   25.73  ? 248 VAL D CB  1 
ATOM   7579 C CG1 . VAL D 2 78  ? -26.491 -20.732 35.681  1   22.46  ? 248 VAL D CG1 1 
ATOM   7580 C CG2 . VAL D 2 78  ? -26.476 -19.365 33.592  1   25.08  ? 248 VAL D CG2 1 
ATOM   7581 N N   . LEU D 2 79  ? -24.001 -22.923 35.349  1   30.44  ? 249 LEU D N   1 
ATOM   7582 C CA  . LEU D 2 79  ? -23.822 -24.1   36.186  1   28.16  ? 249 LEU D CA  1 
ATOM   7583 C C   . LEU D 2 79  ? -25.006 -24.268 37.135  1   30.41  ? 249 LEU D C   1 
ATOM   7584 O O   . LEU D 2 79  ? -25.699 -23.298 37.475  1   29.73  ? 249 LEU D O   1 
ATOM   7585 C CB  . LEU D 2 79  ? -22.506 -24.011 36.943  1   23.62  ? 249 LEU D CB  1 
ATOM   7586 C CG  . LEU D 2 79  ? -21.275 -24.125 36.049  1   24.57  ? 249 LEU D CG  1 
ATOM   7587 C CD1 . LEU D 2 79  ? -20.077 -24.585 36.87   1   21.98  ? 249 LEU D CD1 1 
ATOM   7588 C CD2 . LEU D 2 79  ? -21.51  -25.007 34.806  1   21.09  ? 249 LEU D CD2 1 
ATOM   7589 N N   . ARG D 2 80  ? -25.25  -25.509 37.55   1   30.35  ? 250 ARG D N   1 
ATOM   7590 C CA  . ARG D 2 80  ? -26.425 -25.815 38.405  1   30.48  ? 250 ARG D CA  1 
ATOM   7591 C C   . ARG D 2 80  ? -26.347 -25.033 39.711  1   30.33  ? 250 ARG D C   1 
ATOM   7592 O O   . ARG D 2 80  ? -27.396 -24.594 40.199  1   32.62  ? 250 ARG D O   1 
ATOM   7593 C CB  . ARG D 2 80  ? -26.454 -27.318 38.693  1   29.78  ? 250 ARG D CB  1 
ATOM   7594 C CG  . ARG D 2 80  ? -27.625 -27.802 39.533  1   31.66  ? 250 ARG D CG  1 
ATOM   7595 C CD  . ARG D 2 80  ? -27.304 -29.138 40.167  1   36.64  ? 250 ARG D CD  1 
ATOM   7596 N NE  . ARG D 2 80  ? -25.855 -29.357 40.211  1   41.05  ? 250 ARG D NE  1 
ATOM   7597 C CZ  . ARG D 2 80  ? -25.275 -30.509 40.507  1   38.37  ? 250 ARG D CZ  1 
ATOM   7598 N NH1 . ARG D 2 80  ? -25.646 -31.612 39.887  1   36.48  ? 250 ARG D NH1 1 
ATOM   7599 N NH2 . ARG D 2 80  ? -24.326 -30.553 41.421  1   39.41  ? 250 ARG D NH2 1 
ATOM   7600 N N   . GLY D 2 81  ? -25.143 -24.87  40.241  1   28.75  ? 251 GLY D N   1 
ATOM   7601 C CA  . GLY D 2 81  ? -24.995 -24.207 41.523  1   26.66  ? 251 GLY D CA  1 
ATOM   7602 C C   . GLY D 2 81  ? -25.357 -22.73  41.448  1   25.28  ? 251 GLY D C   1 
ATOM   7603 O O   . GLY D 2 81  ? -25.491 -22.068 42.474  1   27.15  ? 251 GLY D O   1 
ATOM   7604 N N   . LYS D 2 82  ? -25.523 -22.227 40.226  1   24.93  ? 252 LYS D N   1 
ATOM   7605 C CA  . LYS D 2 82  ? -25.735 -20.808 40.021  1   23.86  ? 252 LYS D CA  1 
ATOM   7606 C C   . LYS D 2 82  ? -27.111 -20.552 39.428  1   24.89  ? 252 LYS D C   1 
ATOM   7607 O O   . LYS D 2 82  ? -27.479 -19.392 39.253  1   28.57  ? 252 LYS D O   1 
ATOM   7608 C CB  . LYS D 2 82  ? -24.65  -20.224 39.115  1   22.03  ? 252 LYS D CB  1 
ATOM   7609 C CG  . LYS D 2 82  ? -23.286 -20.176 39.795  1   22.64  ? 252 LYS D CG  1 
ATOM   7610 C CD  . LYS D 2 82  ? -23.372 -19.143 40.911  1   24.32  ? 252 LYS D CD  1 
ATOM   7611 C CE  . LYS D 2 82  ? -22.037 -18.697 41.408  1   23.11  ? 252 LYS D CE  1 
ATOM   7612 N NZ  . LYS D 2 82  ? -21.376 -19.947 41.751  1   24.67  ? 252 LYS D NZ  1 
ATOM   7613 N N   . LEU D 2 83  ? -27.85  -21.62  39.107  1   24.6   ? 253 LEU D N   1 
ATOM   7614 C CA  . LEU D 2 83  ? -29.19  -21.489 38.552  1   23.69  ? 253 LEU D CA  1 
ATOM   7615 C C   . LEU D 2 83  ? -30.076 -20.717 39.531  1   24.23  ? 253 LEU D C   1 
ATOM   7616 O O   . LEU D 2 83  ? -30.784 -19.802 39.143  1   26.24  ? 253 LEU D O   1 
ATOM   7617 C CB  . LEU D 2 83  ? -29.771 -22.862 38.215  1   24.75  ? 253 LEU D CB  1 
ATOM   7618 C CG  . LEU D 2 83  ? -31.162 -22.852 37.571  1   27.49  ? 253 LEU D CG  1 
ATOM   7619 C CD1 . LEU D 2 83  ? -31.186 -22.045 36.264  1   23.81  ? 253 LEU D CD1 1 
ATOM   7620 C CD2 . LEU D 2 83  ? -31.69  -24.27  37.341  1   26.27  ? 253 LEU D CD2 1 
ATOM   7621 N N   . GLN D 2 84  ? -29.972 -21.007 40.825  1   25.56  ? 254 GLN D N   1 
ATOM   7622 C CA  . GLN D 2 84  ? -30.794 -20.27  41.77   1   28.53  ? 254 GLN D CA  1 
ATOM   7623 C C   . GLN D 2 84  ? -30.398 -18.794 41.828  1   28.56  ? 254 GLN D C   1 
ATOM   7624 O O   . GLN D 2 84  ? -31.248 -17.927 42.075  1   29.85  ? 254 GLN D O   1 
ATOM   7625 C CB  . GLN D 2 84  ? -30.779 -20.855 43.177  1   27.94  ? 254 GLN D CB  1 
ATOM   7626 C CG  . GLN D 2 84  ? -31.89  -20.284 44.042  1   27.68  ? 254 GLN D CG  1 
ATOM   7627 C CD  . GLN D 2 84  ? -32.046 -21.016 45.35   1   29.04  ? 254 GLN D CD  1 
ATOM   7628 O OE1 . GLN D 2 84  ? -33.044 -20.824 46.048  1   31.94  ? 254 GLN D OE1 1 
ATOM   7629 N NE2 . GLN D 2 84  ? -31.09  -21.879 45.676  1   28.15  ? 254 GLN D NE2 1 
ATOM   7630 N N   . LEU D 2 85  ? -29.11  -18.513 41.609  1   24.51  ? 255 LEU D N   1 
ATOM   7631 C CA  . LEU D 2 85  ? -28.665 -17.134 41.651  1   23.17  ? 255 LEU D CA  1 
ATOM   7632 C C   . LEU D 2 85  ? -29.374 -16.334 40.562  1   25.59  ? 255 LEU D C   1 
ATOM   7633 O O   . LEU D 2 85  ? -29.852 -15.228 40.816  1   26.19  ? 255 LEU D O   1 
ATOM   7634 C CB  . LEU D 2 85  ? -27.149 -17.031 41.552  1   22.02  ? 255 LEU D CB  1 
ATOM   7635 C CG  . LEU D 2 85  ? -26.591 -15.613 41.678  1   22.09  ? 255 LEU D CG  1 
ATOM   7636 C CD1 . LEU D 2 85  ? -27.203 -14.882 42.879  1   19.76  ? 255 LEU D CD1 1 
ATOM   7637 C CD2 . LEU D 2 85  ? -25.072 -15.629 41.772  1   21.13  ? 255 LEU D CD2 1 
ATOM   7638 N N   . VAL D 2 86  ? -29.455 -16.91  39.353  1   25.87  ? 256 VAL D N   1 
ATOM   7639 C CA  . VAL D 2 86  ? -30.092 -16.256 38.225  1   23.3   ? 256 VAL D CA  1 
ATOM   7640 C C   . VAL D 2 86  ? -31.559 -15.994 38.57   1   24.38  ? 256 VAL D C   1 
ATOM   7641 O O   . VAL D 2 86  ? -32.055 -14.889 38.406  1   24.1   ? 256 VAL D O   1 
ATOM   7642 C CB  . VAL D 2 86  ? -29.944 -17.101 36.95   1   22.3   ? 256 VAL D CB  1 
ATOM   7643 C CG1 . VAL D 2 86  ? -30.755 -16.502 35.808  1   21.59  ? 256 VAL D CG1 1 
ATOM   7644 C CG2 . VAL D 2 86  ? -28.482 -17.242 36.556  1   20.89  ? 256 VAL D CG2 1 
ATOM   7645 N N   . GLY D 2 87  ? -32.242 -17.02  39.075  1   23.94  ? 257 GLY D N   1 
ATOM   7646 C CA  . GLY D 2 87  ? -33.639 -16.914 39.465  1   25.19  ? 257 GLY D CA  1 
ATOM   7647 C C   . GLY D 2 87  ? -33.911 -15.806 40.489  1   25.23  ? 257 GLY D C   1 
ATOM   7648 O O   . GLY D 2 87  ? -34.897 -15.083 40.365  1   22.04  ? 257 GLY D O   1 
ATOM   7649 N N   . THR D 2 88  ? -33.048 -15.676 41.509  1   25.73  ? 258 THR D N   1 
ATOM   7650 C CA  . THR D 2 88  ? -33.281 -14.698 42.571  1   25.13  ? 258 THR D CA  1 
ATOM   7651 C C   . THR D 2 88  ? -33.181 -13.295 41.975  1   26.55  ? 258 THR D C   1 
ATOM   7652 O O   . THR D 2 88  ? -34.052 -12.455 42.202  1   27.99  ? 258 THR D O   1 
ATOM   7653 C CB  . THR D 2 88  ? -32.28  -14.887 43.705  1   23.97  ? 258 THR D CB  1 
ATOM   7654 O OG1 . THR D 2 88  ? -32.309 -16.266 44.046  1   26.07  ? 258 THR D OG1 1 
ATOM   7655 C CG2 . THR D 2 88  ? -32.7   -14.11  44.93   1   27.44  ? 258 THR D CG2 1 
ATOM   7656 N N   . ALA D 2 89  ? -32.121 -13.079 41.177  1   26.18  ? 259 ALA D N   1 
ATOM   7657 C CA  . ALA D 2 89  ? -31.864 -11.82  40.504  1   25.6   ? 259 ALA D CA  1 
ATOM   7658 C C   . ALA D 2 89  ? -33.032 -11.483 39.587  1   27.63  ? 259 ALA D C   1 
ATOM   7659 O O   . ALA D 2 89  ? -33.452 -10.325 39.558  1   30.11  ? 259 ALA D O   1 
ATOM   7660 C CB  . ALA D 2 89  ? -30.565 -11.865 39.75   1   22.52  ? 259 ALA D CB  1 
ATOM   7661 N N   . ALA D 2 90  ? -33.564 -12.495 38.877  1   25.81  ? 260 ALA D N   1 
ATOM   7662 C CA  . ALA D 2 90  ? -34.692 -12.29  37.977  1   25.84  ? 260 ALA D CA  1 
ATOM   7663 C C   . ALA D 2 90  ? -35.947 -11.898 38.758  1   29.32  ? 260 ALA D C   1 
ATOM   7664 O O   . ALA D 2 90  ? -36.67  -10.99  38.343  1   32.58  ? 260 ALA D O   1 
ATOM   7665 C CB  . ALA D 2 90  ? -34.918 -13.498 37.106  1   23.08  ? 260 ALA D CB  1 
ATOM   7666 N N   . MET D 2 91  ? -36.188 -12.566 39.894  1   27.58  ? 261 MET D N   1 
ATOM   7667 C CA  . MET D 2 91  ? -37.34  -12.257 40.723  1   26.87  ? 261 MET D CA  1 
ATOM   7668 C C   . MET D 2 91  ? -37.178 -10.841 41.27   1   29.82  ? 261 MET D C   1 
ATOM   7669 O O   . MET D 2 91  ? -38.164 -10.11  41.383  1   32.49  ? 261 MET D O   1 
ATOM   7670 C CB  . MET D 2 91  ? -37.485 -13.263 41.87   1   26.61  ? 261 MET D CB  1 
ATOM   7671 C CG  . MET D 2 91  ? -38.863 -13.343 42.517  1   29.33  ? 261 MET D CG  1 
ATOM   7672 S SD  . MET D 2 91  ? -40.162 -13.648 41.308  1   34.16  ? 261 MET D SD  1 
ATOM   7673 C CE  . MET D 2 91  ? -41.46  -14.497 42.211  1   31.4   ? 261 MET D CE  1 
ATOM   7674 N N   . LEU D 2 92  ? -35.935 -10.453 41.593  1   26.01  ? 262 LEU D N   1 
ATOM   7675 C CA  . LEU D 2 92  ? -35.693 -9.133  42.15   1   26.07  ? 262 LEU D CA  1 
ATOM   7676 C C   . LEU D 2 92  ? -36.049 -8.055  41.125  1   25.47  ? 262 LEU D C   1 
ATOM   7677 O O   . LEU D 2 92  ? -36.71  -7.063  41.453  1   26.24  ? 262 LEU D O   1 
ATOM   7678 C CB  . LEU D 2 92  ? -34.23  -9.016  42.576  1   23.69  ? 262 LEU D CB  1 
ATOM   7679 C CG  . LEU D 2 92  ? -33.779 -7.637  43.051  1   21.55  ? 262 LEU D CG  1 
ATOM   7680 C CD1 . LEU D 2 92  ? -34.648 -7.142  44.205  1   20.49  ? 262 LEU D CD1 1 
ATOM   7681 C CD2 . LEU D 2 92  ? -32.32  -7.703  43.5    1   21.99  ? 262 LEU D CD2 1 
ATOM   7682 N N   . LEU D 2 93  ? -35.566 -8.252  39.896  1   24.3   ? 263 LEU D N   1 
ATOM   7683 C CA  . LEU D 2 93  ? -35.759 -7.3    38.822  1   25.15  ? 263 LEU D CA  1 
ATOM   7684 C C   . LEU D 2 93  ? -37.25  -7.204  38.503  1   26.42  ? 263 LEU D C   1 
ATOM   7685 O O   . LEU D 2 93  ? -37.761 -6.097  38.314  1   25.93  ? 263 LEU D O   1 
ATOM   7686 C CB  . LEU D 2 93  ? -34.952 -7.759  37.612  1   26.31  ? 263 LEU D CB  1 
ATOM   7687 C CG  . LEU D 2 93  ? -33.47  -7.389  37.626  1   31.83  ? 263 LEU D CG  1 
ATOM   7688 C CD1 . LEU D 2 93  ? -32.727 -8.094  36.493  1   32.57  ? 263 LEU D CD1 1 
ATOM   7689 C CD2 . LEU D 2 93  ? -33.31  -5.877  37.512  1   32.12  ? 263 LEU D CD2 1 
ATOM   7690 N N   . ALA D 2 94  ? -37.939 -8.36   38.502  1   24.11  ? 264 ALA D N   1 
ATOM   7691 C CA  . ALA D 2 94  ? -39.354 -8.386  38.176  1   24.89  ? 264 ALA D CA  1 
ATOM   7692 C C   . ALA D 2 94  ? -40.141 -7.637  39.24   1   26.86  ? 264 ALA D C   1 
ATOM   7693 O O   . ALA D 2 94  ? -41.099 -6.948  38.911  1   31.15  ? 264 ALA D O   1 
ATOM   7694 C CB  . ALA D 2 94  ? -39.851 -9.801  38.032  1   23.63  ? 264 ALA D CB  1 
ATOM   7695 N N   . SER D 2 95  ? -39.734 -7.793  40.508  1   26.14  ? 265 SER D N   1 
ATOM   7696 C CA  . SER D 2 95  ? -40.381 -7.12   41.622  1   25.41  ? 265 SER D CA  1 
ATOM   7697 C C   . SER D 2 95  ? -40.231 -5.608  41.483  1   26.58  ? 265 SER D C   1 
ATOM   7698 O O   . SER D 2 95  ? -41.183 -4.85   41.668  1   28.11  ? 265 SER D O   1 
ATOM   7699 C CB  . SER D 2 95  ? -39.833 -7.607  42.94   1   23.99  ? 265 SER D CB  1 
ATOM   7700 O OG  . SER D 2 95  ? -40.128 -8.984  43.138  1   25.25  ? 265 SER D OG  1 
ATOM   7701 N N   . LYS D 2 96  ? -39.006 -5.174  41.173  1   27.34  ? 266 LYS D N   1 
ATOM   7702 C CA  . LYS D 2 96  ? -38.726 -3.755  41.064  1   25.23  ? 266 LYS D CA  1 
ATOM   7703 C C   . LYS D 2 96  ? -39.476 -3.149  39.876  1   25.17  ? 266 LYS D C   1 
ATOM   7704 O O   . LYS D 2 96  ? -39.873 -1.982  39.947  1   27.34  ? 266 LYS D O   1 
ATOM   7705 C CB  . LYS D 2 96  ? -37.222 -3.497  40.945  1   23.49  ? 266 LYS D CB  1 
ATOM   7706 C CG  . LYS D 2 96  ? -36.379 -3.677  42.206  1   20.41  ? 266 LYS D CG  1 
ATOM   7707 C CD  . LYS D 2 96  ? -34.926 -3.316  41.896  1   20.31  ? 266 LYS D CD  1 
ATOM   7708 C CE  . LYS D 2 96  ? -33.963 -3.443  43.032  1   19.21  ? 266 LYS D CE  1 
ATOM   7709 N NZ  . LYS D 2 96  ? -32.594 -3.226  42.584  1   17.55  ? 266 LYS D NZ  1 
ATOM   7710 N N   . PHE D 2 97  ? -39.656 -3.927  38.795  1   23     ? 267 PHE D N   1 
ATOM   7711 C CA  . PHE D 2 97  ? -40.375 -3.457  37.615  1   23.78  ? 267 PHE D CA  1 
ATOM   7712 C C   . PHE D 2 97  ? -41.859 -3.315  37.932  1   22.05  ? 267 PHE D C   1 
ATOM   7713 O O   . PHE D 2 97  ? -42.437 -2.263  37.703  1   21.62  ? 267 PHE D O   1 
ATOM   7714 C CB  . PHE D 2 97  ? -40.158 -4.359  36.395  1   23.41  ? 267 PHE D CB  1 
ATOM   7715 C CG  . PHE D 2 97  ? -40.845 -3.894  35.118  1   26.31  ? 267 PHE D CG  1 
ATOM   7716 C CD1 . PHE D 2 97  ? -40.245 -2.972  34.265  1   27.88  ? 267 PHE D CD1 1 
ATOM   7717 C CD2 . PHE D 2 97  ? -42.104 -4.378  34.772  1   27.26  ? 267 PHE D CD2 1 
ATOM   7718 C CE1 . PHE D 2 97  ? -40.876 -2.564  33.081  1   31.57  ? 267 PHE D CE1 1 
ATOM   7719 C CE2 . PHE D 2 97  ? -42.733 -3.983  33.593  1   28.75  ? 267 PHE D CE2 1 
ATOM   7720 C CZ  . PHE D 2 97  ? -42.123 -3.072  32.742  1   30.99  ? 267 PHE D CZ  1 
ATOM   7721 N N   . GLU D 2 98  ? -42.429 -4.348  38.553  1   23.46  ? 268 GLU D N   1 
ATOM   7722 C CA  . GLU D 2 98  ? -43.872 -4.543  38.573  1   26.72  ? 268 GLU D CA  1 
ATOM   7723 C C   . GLU D 2 98  ? -44.539 -4.138  39.898  1   28.93  ? 268 GLU D C   1 
ATOM   7724 O O   . GLU D 2 98  ? -45.712 -3.749  39.9    1   29.19  ? 268 GLU D O   1 
ATOM   7725 C CB  . GLU D 2 98  ? -44.158 -6.013  38.278  1   25.24  ? 268 GLU D CB  1 
ATOM   7726 C CG  . GLU D 2 98  ? -45.606 -6.267  37.885  1   28.97  ? 268 GLU D CG  1 
ATOM   7727 C CD  . GLU D 2 98  ? -46.126 -5.392  36.755  1   33.8   ? 268 GLU D CD  1 
ATOM   7728 O OE1 . GLU D 2 98  ? -45.349 -5.127  35.802  1   33.48  ? 268 GLU D OE1 1 
ATOM   7729 O OE2 . GLU D 2 98  ? -47.325 -5.017  36.8    1   30.79  ? 268 GLU D OE2 1 
ATOM   7730 N N   . GLU D 2 99  ? -43.815 -4.244  41.028  1   27.93  ? 269 GLU D N   1 
ATOM   7731 C CA  . GLU D 2 99  ? -44.44  -4.154  42.338  1   24.92  ? 269 GLU D CA  1 
ATOM   7732 C C   . GLU D 2 99  ? -44.485 -2.706  42.805  1   27.22  ? 269 GLU D C   1 
ATOM   7733 O O   . GLU D 2 99  ? -43.544 -1.941  42.6    1   32.16  ? 269 GLU D O   1 
ATOM   7734 C CB  . GLU D 2 99  ? -43.699 -4.994  43.374  1   22.67  ? 269 GLU D CB  1 
ATOM   7735 C CG  . GLU D 2 99  ? -43.831 -6.505  43.182  1   23.85  ? 269 GLU D CG  1 
ATOM   7736 C CD  . GLU D 2 99  ? -45.202 -7.15   43.376  1   26.18  ? 269 GLU D CD  1 
ATOM   7737 O OE1 . GLU D 2 99  ? -45.98  -6.681  44.244  1   29.02  ? 269 GLU D OE1 1 
ATOM   7738 O OE2 . GLU D 2 99  ? -45.48  -8.159  42.695  1   23.32  ? 269 GLU D OE2 1 
ATOM   7739 N N   . ILE D 2 100 ? -45.576 -2.344  43.483  1   26.84  ? 270 ILE D N   1 
ATOM   7740 C CA  . ILE D 2 100 ? -45.634 -1.075  44.183  1   25.55  ? 270 ILE D CA  1 
ATOM   7741 C C   . ILE D 2 100 ? -44.619 -1.048  45.331  1   28.4   ? 270 ILE D C   1 
ATOM   7742 O O   . ILE D 2 100 ? -43.97  -0.023  45.546  1   29.36  ? 270 ILE D O   1 
ATOM   7743 C CB  . ILE D 2 100 ? -47.045 -0.811  44.71   1   25.3   ? 270 ILE D CB  1 
ATOM   7744 C CG1 . ILE D 2 100 ? -48.114 -0.788  43.611  1   24.93  ? 270 ILE D CG1 1 
ATOM   7745 C CG2 . ILE D 2 100 ? -47.061 0.48    45.53   1   25.1   ? 270 ILE D CG2 1 
ATOM   7746 C CD1 . ILE D 2 100 ? -49.539 -0.733  44.175  1   21.24  ? 270 ILE D CD1 1 
ATOM   7747 N N   . TYR D 2 101 ? -44.531 -2.163  46.083  1   30.1   ? 271 TYR D N   1 
ATOM   7748 C CA  . TYR D 2 101 ? -43.684 -2.319  47.261  1   28.95  ? 271 TYR D CA  1 
ATOM   7749 C C   . TYR D 2 101 ? -42.855 -3.592  47.104  1   30.11  ? 271 TYR D C   1 
ATOM   7750 O O   . TYR D 2 101 ? -43.173 -4.61   47.73   1   28.44  ? 271 TYR D O   1 
ATOM   7751 C CB  . TYR D 2 101 ? -44.468 -2.424  48.58   1   27.31  ? 271 TYR D CB  1 
ATOM   7752 C CG  . TYR D 2 101 ? -45.406 -1.256  48.845  1   29.14  ? 271 TYR D CG  1 
ATOM   7753 C CD1 . TYR D 2 101 ? -44.911 -0.036  49.298  1   27.87  ? 271 TYR D CD1 1 
ATOM   7754 C CD2 . TYR D 2 101 ? -46.782 -1.361  48.595  1   31.39  ? 271 TYR D CD2 1 
ATOM   7755 C CE1 . TYR D 2 101 ? -45.758 1.045   49.504  1   29.83  ? 271 TYR D CE1 1 
ATOM   7756 C CE2 . TYR D 2 101 ? -47.641 -0.295  48.828  1   30.68  ? 271 TYR D CE2 1 
ATOM   7757 C CZ  . TYR D 2 101 ? -47.121 0.911   49.274  1   32.32  ? 271 TYR D CZ  1 
ATOM   7758 O OH  . TYR D 2 101 ? -47.957 1.966   49.487  1   37.62  ? 271 TYR D OH  1 
ATOM   7759 N N   . PRO D 2 102 ? -41.78  -3.582  46.269  1   28.83  ? 272 PRO D N   1 
ATOM   7760 C CA  . PRO D 2 102 ? -40.925 -4.762  46.122  1   25.8   ? 272 PRO D CA  1 
ATOM   7761 C C   . PRO D 2 102 ? -40.326 -5.135  47.482  1   27.13  ? 272 PRO D C   1 
ATOM   7762 O O   . PRO D 2 102 ? -40.078 -4.28   48.347  1   23.61  ? 272 PRO D O   1 
ATOM   7763 C CB  . PRO D 2 102 ? -39.831 -4.294  45.16   1   25.57  ? 272 PRO D CB  1 
ATOM   7764 C CG  . PRO D 2 102 ? -39.856 -2.793  45.258  1   26.21  ? 272 PRO D CG  1 
ATOM   7765 C CD  . PRO D 2 102 ? -41.315 -2.433  45.471  1   26     ? 272 PRO D CD  1 
ATOM   7766 N N   . PRO D 2 103 ? -40.067 -6.436  47.725  1   25.33  ? 273 PRO D N   1 
ATOM   7767 C CA  . PRO D 2 103 ? -39.258 -6.804  48.876  1   24.42  ? 273 PRO D CA  1 
ATOM   7768 C C   . PRO D 2 103 ? -37.872 -6.184  48.661  1   29.29  ? 273 PRO D C   1 
ATOM   7769 O O   . PRO D 2 103 ? -37.434 -5.94   47.524  1   27.73  ? 273 PRO D O   1 
ATOM   7770 C CB  . PRO D 2 103 ? -39.244 -8.335  48.809  1   23.34  ? 273 PRO D CB  1 
ATOM   7771 C CG  . PRO D 2 103 ? -40.378 -8.729  47.885  1   24.34  ? 273 PRO D CG  1 
ATOM   7772 C CD  . PRO D 2 103 ? -40.536 -7.58   46.919  1   24.44  ? 273 PRO D CD  1 
ATOM   7773 N N   . GLU D 2 104 ? -37.172 -5.949  49.78   1   29.71  ? 274 GLU D N   1 
ATOM   7774 C CA  . GLU D 2 104 ? -35.822 -5.43   49.768  1   28.9   ? 274 GLU D CA  1 
ATOM   7775 C C   . GLU D 2 104 ? -34.867 -6.526  49.319  1   27.77  ? 274 GLU D C   1 
ATOM   7776 O O   . GLU D 2 104 ? -35.198 -7.712  49.369  1   25.36  ? 274 GLU D O   1 
ATOM   7777 C CB  . GLU D 2 104 ? -35.473 -4.984  51.185  1   34.15  ? 274 GLU D CB  1 
ATOM   7778 C CG  . GLU D 2 104 ? -36.063 -3.632  51.569  1   43.3   ? 274 GLU D CG  1 
ATOM   7779 C CD  . GLU D 2 104 ? -35.717 -3.244  52.999  1   60.19  ? 274 GLU D CD  1 
ATOM   7780 O OE1 . GLU D 2 104 ? -36.274 -2.229  53.473  1   69.29  ? 274 GLU D OE1 1 
ATOM   7781 O OE2 . GLU D 2 104 ? -34.897 -3.938  53.649  1   62.94  ? 274 GLU D OE2 1 
ATOM   7782 N N   . VAL D 2 105 ? -33.661 -6.118  48.901  1   27.14  ? 275 VAL D N   1 
ATOM   7783 C CA  . VAL D 2 105 ? -32.678 -7.095  48.459  1   29.62  ? 275 VAL D CA  1 
ATOM   7784 C C   . VAL D 2 105 ? -32.377 -8.12   49.566  1   29.54  ? 275 VAL D C   1 
ATOM   7785 O O   . VAL D 2 105 ? -32.181 -9.304  49.287  1   27.85  ? 275 VAL D O   1 
ATOM   7786 C CB  . VAL D 2 105 ? -31.403 -6.421  47.91   1   29.51  ? 275 VAL D CB  1 
ATOM   7787 C CG1 . VAL D 2 105 ? -30.42  -7.454  47.379  1   25.11  ? 275 VAL D CG1 1 
ATOM   7788 C CG2 . VAL D 2 105 ? -31.742 -5.403  46.825  1   31.03  ? 275 VAL D CG2 1 
ATOM   7789 N N   . ALA D 2 106 ? -32.34  -7.67   50.828  1   28.12  ? 276 ALA D N   1 
ATOM   7790 C CA  . ALA D 2 106 ? -32.007 -8.569  51.924  1   31.45  ? 276 ALA D CA  1 
ATOM   7791 C C   . ALA D 2 106 ? -33.002 -9.73   52.008  1   33.86  ? 276 ALA D C   1 
ATOM   7792 O O   . ALA D 2 106 ? -32.645 -10.817 52.457  1   35.08  ? 276 ALA D O   1 
ATOM   7793 C CB  . ALA D 2 106 ? -31.97  -7.812  53.229  1   28.23  ? 276 ALA D CB  1 
ATOM   7794 N N   . GLU D 2 107 ? -34.263 -9.478  51.633  1   32.93  ? 277 GLU D N   1 
ATOM   7795 C CA  . GLU D 2 107 ? -35.3   -10.496 51.695  1   34.44  ? 277 GLU D CA  1 
ATOM   7796 C C   . GLU D 2 107 ? -35     -11.545 50.626  1   33.38  ? 277 GLU D C   1 
ATOM   7797 O O   . GLU D 2 107 ? -35.279 -12.729 50.814  1   35.99  ? 277 GLU D O   1 
ATOM   7798 C CB  . GLU D 2 107 ? -36.704 -9.885  51.599  1   38.36  ? 277 GLU D CB  1 
ATOM   7799 C CG  . GLU D 2 107 ? -37.167 -9.158  52.866  1   49.1   ? 277 GLU D CG  1 
ATOM   7800 C CD  . GLU D 2 107 ? -38.294 -8.127  52.711  1   63.89  ? 277 GLU D CD  1 
ATOM   7801 O OE1 . GLU D 2 107 ? -39.494 -8.438  52.923  1   62.02  ? 277 GLU D OE1 1 
ATOM   7802 O OE2 . GLU D 2 107 ? -37.98  -6.965  52.365  1   71.72  ? 277 GLU D OE2 1 
ATOM   7803 N N   . PHE D 2 108 ? -34.397 -11.11  49.509  1   31     ? 278 PHE D N   1 
ATOM   7804 C CA  . PHE D 2 108 ? -34.101 -12.01  48.404  1   27.41  ? 278 PHE D CA  1 
ATOM   7805 C C   . PHE D 2 108 ? -32.922 -12.922 48.743  1   29.45  ? 278 PHE D C   1 
ATOM   7806 O O   . PHE D 2 108 ? -32.82  -14.035 48.199  1   30.37  ? 278 PHE D O   1 
ATOM   7807 C CB  . PHE D 2 108 ? -33.877 -11.201 47.125  1   23.74  ? 278 PHE D CB  1 
ATOM   7808 C CG  . PHE D 2 108 ? -35.174 -10.817 46.449  1   23.63  ? 278 PHE D CG  1 
ATOM   7809 C CD1 . PHE D 2 108 ? -35.848 -11.735 45.644  1   24.21  ? 278 PHE D CD1 1 
ATOM   7810 C CD2 . PHE D 2 108 ? -35.745 -9.567  46.66   1   23.37  ? 278 PHE D CD2 1 
ATOM   7811 C CE1 . PHE D 2 108 ? -37.048 -11.39  45.024  1   24.45  ? 278 PHE D CE1 1 
ATOM   7812 C CE2 . PHE D 2 108 ? -36.951 -9.233  46.052  1   24.86  ? 278 PHE D CE2 1 
ATOM   7813 C CZ  . PHE D 2 108 ? -37.597 -10.131 45.216  1   23.97  ? 278 PHE D CZ  1 
ATOM   7814 N N   . VAL D 2 109 ? -32.019 -12.432 49.61   1   30.75  ? 279 VAL D N   1 
ATOM   7815 C CA  . VAL D 2 109 ? -30.847 -13.195 50.023  1   31.82  ? 279 VAL D CA  1 
ATOM   7816 C C   . VAL D 2 109 ? -31.258 -14.253 51.048  1   34.1   ? 279 VAL D C   1 
ATOM   7817 O O   . VAL D 2 109 ? -30.68  -15.335 51.103  1   37.43  ? 279 VAL D O   1 
ATOM   7818 C CB  . VAL D 2 109 ? -29.717 -12.29  50.551  1   31.91  ? 279 VAL D CB  1 
ATOM   7819 C CG1 . VAL D 2 109 ? -28.516 -13.096 51.05   1   29.03  ? 279 VAL D CG1 1 
ATOM   7820 C CG2 . VAL D 2 109 ? -29.292 -11.28  49.488  1   30.44  ? 279 VAL D CG2 1 
ATOM   7821 N N   . TYR D 2 110 ? -32.278 -13.926 51.848  1   33.02  ? 280 TYR D N   1 
ATOM   7822 C CA  . TYR D 2 110 ? -32.755 -14.792 52.904  1   31.42  ? 280 TYR D CA  1 
ATOM   7823 C C   . TYR D 2 110 ? -33.49  -15.993 52.312  1   31.51  ? 280 TYR D C   1 
ATOM   7824 O O   . TYR D 2 110 ? -33.314 -17.103 52.798  1   35.32  ? 280 TYR D O   1 
ATOM   7825 C CB  . TYR D 2 110 ? -33.632 -13.94  53.821  1   37.07  ? 280 TYR D CB  1 
ATOM   7826 C CG  . TYR D 2 110 ? -34.345 -14.739 54.903  1   49.84  ? 280 TYR D CG  1 
ATOM   7827 C CD1 . TYR D 2 110 ? -33.729 -14.981 56.124  1   53.56  ? 280 TYR D CD1 1 
ATOM   7828 C CD2 . TYR D 2 110 ? -35.625 -15.257 54.702  1   52.2   ? 280 TYR D CD2 1 
ATOM   7829 C CE1 . TYR D 2 110 ? -34.376 -15.684 57.127  1   55.69  ? 280 TYR D CE1 1 
ATOM   7830 C CE2 . TYR D 2 110 ? -36.269 -15.989 55.685  1   51.06  ? 280 TYR D CE2 1 
ATOM   7831 C CZ  . TYR D 2 110 ? -35.642 -16.199 56.899  1   55.12  ? 280 TYR D CZ  1 
ATOM   7832 O OH  . TYR D 2 110 ? -36.287 -16.914 57.863  1   58.51  ? 280 TYR D OH  1 
ATOM   7833 N N   . ILE D 2 111 ? -34.282 -15.794 51.249  1   33.31  ? 281 ILE D N   1 
ATOM   7834 C CA  . ILE D 2 111 ? -35.067 -16.89  50.68   1   38.66  ? 281 ILE D CA  1 
ATOM   7835 C C   . ILE D 2 111 ? -34.19  -17.97  50.034  1   40.17  ? 281 ILE D C   1 
ATOM   7836 O O   . ILE D 2 111 ? -34.7   -19.054 49.756  1   40.95  ? 281 ILE D O   1 
ATOM   7837 C CB  . ILE D 2 111 ? -36.089 -16.389 49.652  1   38.22  ? 281 ILE D CB  1 
ATOM   7838 C CG1 . ILE D 2 111 ? -35.364 -15.692 48.504  1   40.16  ? 281 ILE D CG1 1 
ATOM   7839 C CG2 . ILE D 2 111 ? -37.126 -15.496 50.315  1   38.49  ? 281 ILE D CG2 1 
ATOM   7840 C CD1 . ILE D 2 111 ? -36.231 -15.303 47.321  1   41.98  ? 281 ILE D CD1 1 
ATOM   7841 N N   . THR D 2 112 ? -32.909 -17.664 49.76   1   40.47  ? 282 THR D N   1 
ATOM   7842 C CA  . THR D 2 112 ? -31.975 -18.635 49.198  1   39.94  ? 282 THR D CA  1 
ATOM   7843 C C   . THR D 2 112 ? -31.293 -19.411 50.314  1   44.44  ? 282 THR D C   1 
ATOM   7844 O O   . THR D 2 112 ? -30.323 -20.112 50.029  1   50.11  ? 282 THR D O   1 
ATOM   7845 C CB  . THR D 2 112 ? -30.901 -18.019 48.292  1   35.73  ? 282 THR D CB  1 
ATOM   7846 O OG1 . THR D 2 112 ? -29.96  -17.319 49.106  1   32.62  ? 282 THR D OG1 1 
ATOM   7847 C CG2 . THR D 2 112 ? -31.466 -17.15  47.185  1   28.51  ? 282 THR D CG2 1 
ATOM   7848 N N   . ASP D 2 113 ? -31.781 -19.254 51.559  1   53.01  ? 283 ASP D N   1 
ATOM   7849 C CA  . ASP D 2 113 ? -31.146 -19.791 52.764  1   56.25  ? 283 ASP D CA  1 
ATOM   7850 C C   . ASP D 2 113 ? -29.664 -19.446 52.766  1   52.66  ? 283 ASP D C   1 
ATOM   7851 O O   . ASP D 2 113 ? -28.821 -20.324 52.948  1   51.48  ? 283 ASP D O   1 
ATOM   7852 C CB  . ASP D 2 113 ? -31.343 -21.293 52.915  1   64.68  ? 283 ASP D CB  1 
ATOM   7853 C CG  . ASP D 2 113 ? -32.767 -21.715 53.226  1   75.36  ? 283 ASP D CG  1 
ATOM   7854 O OD1 . ASP D 2 113 ? -33.7   -21.097 52.645  1   84.29  ? 283 ASP D OD1 1 
ATOM   7855 O OD2 . ASP D 2 113 ? -32.921 -22.65  54.038  1   77.3   ? 283 ASP D OD2 1 
ATOM   7856 N N   . ASP D 2 114 ? -29.371 -18.164 52.52   1   54.34  ? 284 ASP D N   1 
ATOM   7857 C CA  . ASP D 2 114 ? -27.999 -17.677 52.433  1   62.36  ? 284 ASP D CA  1 
ATOM   7858 C C   . ASP D 2 114 ? -27.112 -18.638 51.625  1   55.68  ? 284 ASP D C   1 
ATOM   7859 O O   . ASP D 2 114 ? -25.976 -18.928 52.002  1   48.86  ? 284 ASP D O   1 
ATOM   7860 C CB  . ASP D 2 114 ? -27.445 -17.373 53.819  1   71.85  ? 284 ASP D CB  1 
ATOM   7861 C CG  . ASP D 2 114 ? -28.383 -16.62  54.751  1   74.08  ? 284 ASP D CG  1 
ATOM   7862 O OD1 . ASP D 2 114 ? -29.386 -16.044 54.252  1   80.03  ? 284 ASP D OD1 1 
ATOM   7863 O OD2 . ASP D 2 114 ? -28.12  -16.657 55.967  1   73.36  ? 284 ASP D OD2 1 
ATOM   7864 N N   . THR D 2 115 ? -27.63  -19.141 50.498  1   50.23  ? 285 THR D N   1 
ATOM   7865 C CA  . THR D 2 115 ? -26.802 -19.906 49.58   1   47.57  ? 285 THR D CA  1 
ATOM   7866 C C   . THR D 2 115 ? -25.797 -18.946 48.918  1   42.61  ? 285 THR D C   1 
ATOM   7867 O O   . THR D 2 115 ? -24.728 -19.354 48.454  1   39.58  ? 285 THR D O   1 
ATOM   7868 C CB  . THR D 2 115 ? -27.7   -20.659 48.583  1   51.95  ? 285 THR D CB  1 
ATOM   7869 O OG1 . THR D 2 115 ? -28.49  -21.64  49.255  1   48.14  ? 285 THR D OG1 1 
ATOM   7870 C CG2 . THR D 2 115 ? -26.924 -21.385 47.494  1   47.22  ? 285 THR D CG2 1 
ATOM   7871 N N   . TYR D 2 116 ? -26.167 -17.659 48.867  1   36.42  ? 286 TYR D N   1 
ATOM   7872 C CA  . TYR D 2 116 ? -25.409 -16.627 48.183  1   34.03  ? 286 TYR D CA  1 
ATOM   7873 C C   . TYR D 2 116 ? -25.3   -15.377 49.054  1   32.67  ? 286 TYR D C   1 
ATOM   7874 O O   . TYR D 2 116 ? -26.178 -15.098 49.862  1   33.27  ? 286 TYR D O   1 
ATOM   7875 C CB  . TYR D 2 116 ? -26.091 -16.245 46.865  1   28.82  ? 286 TYR D CB  1 
ATOM   7876 C CG  . TYR D 2 116 ? -26.444 -17.403 45.95   1   30.61  ? 286 TYR D CG  1 
ATOM   7877 C CD1 . TYR D 2 116 ? -25.46  -18.157 45.306  1   31.88  ? 286 TYR D CD1 1 
ATOM   7878 C CD2 . TYR D 2 116 ? -27.77  -17.714 45.692  1   28.61  ? 286 TYR D CD2 1 
ATOM   7879 C CE1 . TYR D 2 116 ? -25.785 -19.215 44.464  1   29.88  ? 286 TYR D CE1 1 
ATOM   7880 C CE2 . TYR D 2 116 ? -28.104 -18.763 44.853  1   28.22  ? 286 TYR D CE2 1 
ATOM   7881 C CZ  . TYR D 2 116 ? -27.117 -19.515 44.235  1   29.8   ? 286 TYR D CZ  1 
ATOM   7882 O OH  . TYR D 2 116 ? -27.457 -20.547 43.403  1   33.54  ? 286 TYR D OH  1 
ATOM   7883 N N   . THR D 2 117 ? -24.234 -14.597 48.836  1   31.28  ? 287 THR D N   1 
ATOM   7884 C CA  . THR D 2 117 ? -24.088 -13.29  49.462  1   32.8   ? 287 THR D CA  1 
ATOM   7885 C C   . THR D 2 117 ? -24.997 -12.282 48.758  1   30.77  ? 287 THR D C   1 
ATOM   7886 O O   . THR D 2 117 ? -25.377 -12.483 47.609  1   29.45  ? 287 THR D O   1 
ATOM   7887 C CB  . THR D 2 117 ? -22.625 -12.839 49.445  1   34.46  ? 287 THR D CB  1 
ATOM   7888 O OG1 . THR D 2 117 ? -22.301 -12.481 48.106  1   35.07  ? 287 THR D OG1 1 
ATOM   7889 C CG2 . THR D 2 117 ? -21.672 -13.93  49.897  1   33.57  ? 287 THR D CG2 1 
ATOM   7890 N N   . LYS D 2 118 ? -25.328 -11.19  49.457  1   30.87  ? 288 LYS D N   1 
ATOM   7891 C CA  . LYS D 2 118 ? -26.028 -10.067 48.847  1   31.07  ? 288 LYS D CA  1 
ATOM   7892 C C   . LYS D 2 118 ? -25.259 -9.546  47.628  1   30.98  ? 288 LYS D C   1 
ATOM   7893 O O   . LYS D 2 118 ? -25.872 -9.161  46.629  1   30.38  ? 288 LYS D O   1 
ATOM   7894 C CB  . LYS D 2 118 ? -26.207 -8.952  49.881  1   29.7   ? 288 LYS D CB  1 
ATOM   7895 C CG  . LYS D 2 118 ? -27.224 -7.854  49.605  1   30.32  ? 288 LYS D CG  1 
ATOM   7896 C CD  . LYS D 2 118 ? -27.111 -6.916  50.807  1   32.49  ? 288 LYS D CD  1 
ATOM   7897 C CE  . LYS D 2 118 ? -28.149 -5.911  51.169  1   31.92  ? 288 LYS D CE  1 
ATOM   7898 N NZ  . LYS D 2 118 ? -27.689 -5.285  52.417  1   31.69  ? 288 LYS D NZ  1 
ATOM   7899 N N   . LYS D 2 119 ? -23.92  -9.523  47.722  1   30.67  ? 289 LYS D N   1 
ATOM   7900 C CA  . LYS D 2 119 ? -23.08  -8.981  46.667  1   32.01  ? 289 LYS D CA  1 
ATOM   7901 C C   . LYS D 2 119 ? -23.287 -9.78   45.379  1   29.56  ? 289 LYS D C   1 
ATOM   7902 O O   . LYS D 2 119 ? -23.52  -9.207  44.317  1   27.92  ? 289 LYS D O   1 
ATOM   7903 C CB  . LYS D 2 119 ? -21.621 -8.951  47.122  1   38.93  ? 289 LYS D CB  1 
ATOM   7904 C CG  . LYS D 2 119 ? -20.648 -8.334  46.124  1   47.28  ? 289 LYS D CG  1 
ATOM   7905 C CD  . LYS D 2 119 ? -19.19  -8.245  46.567  1   53.27  ? 289 LYS D CD  1 
ATOM   7906 C CE  . LYS D 2 119 ? -18.329 -7.643  45.489  1   53.15  ? 289 LYS D CE  1 
ATOM   7907 N NZ  . LYS D 2 119 ? -16.913 -7.537  45.871  1   49.21  ? 289 LYS D NZ  1 
ATOM   7908 N N   . GLN D 2 120 ? -23.257 -11.112 45.494  1   27.49  ? 290 GLN D N   1 
ATOM   7909 C CA  . GLN D 2 120 ? -23.589 -11.975 44.372  1   28.46  ? 290 GLN D CA  1 
ATOM   7910 C C   . GLN D 2 120 ? -24.949 -11.611 43.773  1   27.29  ? 290 GLN D C   1 
ATOM   7911 O O   . GLN D 2 120 ? -25.077 -11.456 42.559  1   28.84  ? 290 GLN D O   1 
ATOM   7912 C CB  . GLN D 2 120 ? -23.558 -13.428 44.814  1   30.13  ? 290 GLN D CB  1 
ATOM   7913 C CG  . GLN D 2 120 ? -22.155 -13.94  45.099  1   32.92  ? 290 GLN D CG  1 
ATOM   7914 C CD  . GLN D 2 120 ? -22.176 -15.371 45.576  1   36.26  ? 290 GLN D CD  1 
ATOM   7915 O OE1 . GLN D 2 120 ? -22.74  -15.685 46.632  1   39.72  ? 290 GLN D OE1 1 
ATOM   7916 N NE2 . GLN D 2 120 ? -21.625 -16.257 44.759  1   35.79  ? 290 GLN D NE2 1 
ATOM   7917 N N   . VAL D 2 121 ? -25.964 -11.471 44.617  1   23.77  ? 291 VAL D N   1 
ATOM   7918 C CA  . VAL D 2 121 ? -27.289 -11.156 44.112  1   26.28  ? 291 VAL D CA  1 
ATOM   7919 C C   . VAL D 2 121 ? -27.266 -9.84   43.325  1   26.21  ? 291 VAL D C   1 
ATOM   7920 O O   . VAL D 2 121 ? -27.844 -9.759  42.247  1   27.48  ? 291 VAL D O   1 
ATOM   7921 C CB  . VAL D 2 121 ? -28.348 -11.164 45.236  1   25.17  ? 291 VAL D CB  1 
ATOM   7922 C CG1 . VAL D 2 121 ? -29.68  -10.639 44.751  1   23.95  ? 291 VAL D CG1 1 
ATOM   7923 C CG2 . VAL D 2 121 ? -28.52  -12.548 45.845  1   21.14  ? 291 VAL D CG2 1 
ATOM   7924 N N   . LEU D 2 122 ? -26.576 -8.808  43.835  1   28.02  ? 292 LEU D N   1 
ATOM   7925 C CA  . LEU D 2 122 ? -26.589 -7.5    43.182  1   29.18  ? 292 LEU D CA  1 
ATOM   7926 C C   . LEU D 2 122 ? -25.782 -7.516  41.882  1   28.9   ? 292 LEU D C   1 
ATOM   7927 O O   . LEU D 2 122 ? -26.151 -6.881  40.885  1   29.02  ? 292 LEU D O   1 
ATOM   7928 C CB  . LEU D 2 122 ? -26.075 -6.456  44.163  1   28.68  ? 292 LEU D CB  1 
ATOM   7929 C CG  . LEU D 2 122 ? -26.995 -6.205  45.364  1   35.26  ? 292 LEU D CG  1 
ATOM   7930 C CD1 . LEU D 2 122 ? -26.314 -5.316  46.39   1   38.54  ? 292 LEU D CD1 1 
ATOM   7931 C CD2 . LEU D 2 122 ? -28.33  -5.603  44.951  1   35.94  ? 292 LEU D CD2 1 
ATOM   7932 N N   . ARG D 2 123 ? -24.685 -8.274  41.899  1   26.12  ? 293 ARG D N   1 
ATOM   7933 C CA  . ARG D 2 123 ? -23.863 -8.408  40.718  1   26.97  ? 293 ARG D CA  1 
ATOM   7934 C C   . ARG D 2 123 ? -24.647 -9.175  39.658  1   25.7   ? 293 ARG D C   1 
ATOM   7935 O O   . ARG D 2 123 ? -24.609 -8.794  38.507  1   25.98  ? 293 ARG D O   1 
ATOM   7936 C CB  . ARG D 2 123 ? -22.459 -8.905  41.074  1   29.15  ? 293 ARG D CB  1 
ATOM   7937 C CG  . ARG D 2 123 ? -21.566 -7.855  41.727  1   31.82  ? 293 ARG D CG  1 
ATOM   7938 C CD  . ARG D 2 123 ? -20.19  -8.33   42.186  1   46.01  ? 293 ARG D CD  1 
ATOM   7939 N NE  . ARG D 2 123 ? -19.406 -9.001  41.14   1   70.07  ? 293 ARG D NE  1 
ATOM   7940 C CZ  . ARG D 2 123 ? -19.113 -10.314 41.012  1   80.06  ? 293 ARG D CZ  1 
ATOM   7941 N NH1 . ARG D 2 123 ? -19.46  -11.219 41.935  1   71.93  ? 293 ARG D NH1 1 
ATOM   7942 N NH2 . ARG D 2 123 ? -18.475 -10.712 39.918  1   75.93  ? 293 ARG D NH2 1 
ATOM   7943 N N   . MET D 2 124 ? -25.405 -10.209 40.054  1   26.62  ? 294 MET D N   1 
ATOM   7944 C CA  . MET D 2 124 ? -26.19  -10.988 39.111  1   25.19  ? 294 MET D CA  1 
ATOM   7945 C C   . MET D 2 124 ? -27.295 -10.117 38.538  1   23.91  ? 294 MET D C   1 
ATOM   7946 O O   . MET D 2 124 ? -27.596 -10.207 37.351  1   28     ? 294 MET D O   1 
ATOM   7947 C CB  . MET D 2 124 ? -26.841 -12.225 39.732  1   26     ? 294 MET D CB  1 
ATOM   7948 C CG  . MET D 2 124 ? -27.587 -13.11  38.717  1   25.38  ? 294 MET D CG  1 
ATOM   7949 S SD  . MET D 2 124 ? -26.629 -13.816 37.349  1   30.21  ? 294 MET D SD  1 
ATOM   7950 C CE  . MET D 2 124 ? -25.822 -15.187 38.187  1   29.03  ? 294 MET D CE  1 
ATOM   7951 N N   . GLU D 2 125 ? -27.854 -9.255  39.373  1   21.97  ? 295 GLU D N   1 
ATOM   7952 C CA  . GLU D 2 125 ? -28.839 -8.293  38.906  1   24.25  ? 295 GLU D CA  1 
ATOM   7953 C C   . GLU D 2 125 ? -28.275 -7.458  37.748  1   26.3   ? 295 GLU D C   1 
ATOM   7954 O O   . GLU D 2 125 ? -28.924 -7.29   36.721  1   27.32  ? 295 GLU D O   1 
ATOM   7955 C CB  . GLU D 2 125 ? -29.328 -7.42   40.064  1   23.89  ? 295 GLU D CB  1 
ATOM   7956 C CG  . GLU D 2 125 ? -30.351 -6.377  39.628  1   23.97  ? 295 GLU D CG  1 
ATOM   7957 C CD  . GLU D 2 125 ? -30.748 -5.336  40.653  1   29.51  ? 295 GLU D CD  1 
ATOM   7958 O OE1 . GLU D 2 125 ? -29.88  -4.5    41.038  1   31.15  ? 295 GLU D OE1 1 
ATOM   7959 O OE2 . GLU D 2 125 ? -31.947 -5.331  41.04   1   30.27  ? 295 GLU D OE2 1 
ATOM   7960 N N   . HIS D 2 126 ? -27.052 -6.945  37.896  1   29.15  ? 296 HIS D N   1 
ATOM   7961 C CA  . HIS D 2 126 ? -26.459 -6.108  36.863  1   30.49  ? 296 HIS D CA  1 
ATOM   7962 C C   . HIS D 2 126 ? -26.245 -6.923  35.584  1   30.72  ? 296 HIS D C   1 
ATOM   7963 O O   . HIS D 2 126 ? -26.6   -6.477  34.49   1   31.5   ? 296 HIS D O   1 
ATOM   7964 C CB  . HIS D 2 126 ? -25.193 -5.381  37.355  1   29.59  ? 296 HIS D CB  1 
ATOM   7965 C CG  . HIS D 2 126 ? -24.932 -4.137  36.568  1   34.93  ? 296 HIS D CG  1 
ATOM   7966 N ND1 . HIS D 2 126 ? -23.869 -3.302  36.81   1   38.4   ? 296 HIS D ND1 1 
ATOM   7967 C CD2 . HIS D 2 126 ? -25.573 -3.604  35.495  1   38     ? 296 HIS D CD2 1 
ATOM   7968 C CE1 . HIS D 2 126 ? -23.896 -2.295  35.944  1   40.11  ? 296 HIS D CE1 1 
ATOM   7969 N NE2 . HIS D 2 126 ? -24.924 -2.457  35.138  1   39.35  ? 296 HIS D NE2 1 
ATOM   7970 N N   . LEU D 2 127 ? -25.712 -8.139  35.745  1   28.5   ? 297 LEU D N   1 
ATOM   7971 C CA  . LEU D 2 127 ? -25.398 -8.975  34.601  1   29.09  ? 297 LEU D CA  1 
ATOM   7972 C C   . LEU D 2 127 ? -26.674 -9.283  33.817  1   29.04  ? 297 LEU D C   1 
ATOM   7973 O O   . LEU D 2 127 ? -26.662 -9.212  32.59   1   31.98  ? 297 LEU D O   1 
ATOM   7974 C CB  . LEU D 2 127 ? -24.696 -10.267 35.024  1   24.95  ? 297 LEU D CB  1 
ATOM   7975 C CG  . LEU D 2 127 ? -24.347 -11.231 33.88   1   21.86  ? 297 LEU D CG  1 
ATOM   7976 C CD1 . LEU D 2 127 ? -23.353 -10.582 32.919  1   19.99  ? 297 LEU D CD1 1 
ATOM   7977 C CD2 . LEU D 2 127 ? -23.781 -12.536 34.409  1   21.12  ? 297 LEU D CD2 1 
ATOM   7978 N N   . VAL D 2 128 ? -27.755 -9.614  34.532  1   26.97  ? 298 VAL D N   1 
ATOM   7979 C CA  . VAL D 2 128 ? -29.021 -9.918  33.877  1   27.76  ? 298 VAL D CA  1 
ATOM   7980 C C   . VAL D 2 128 ? -29.531 -8.709  33.097  1   29.19  ? 298 VAL D C   1 
ATOM   7981 O O   . VAL D 2 128 ? -30.049 -8.869  31.986  1   36.2   ? 298 VAL D O   1 
ATOM   7982 C CB  . VAL D 2 128 ? -30.093 -10.441 34.844  1   25.7   ? 298 VAL D CB  1 
ATOM   7983 C CG1 . VAL D 2 128 ? -31.458 -10.56  34.159  1   24.05  ? 298 VAL D CG1 1 
ATOM   7984 C CG2 . VAL D 2 128 ? -29.677 -11.79  35.417  1   23.47  ? 298 VAL D CG2 1 
ATOM   7985 N N   . LEU D 2 129 ? -29.367 -7.516  33.682  1   28.14  ? 299 LEU D N   1 
ATOM   7986 C CA  . LEU D 2 129 ? -29.81  -6.29   33.036  1   29.17  ? 299 LEU D CA  1 
ATOM   7987 C C   . LEU D 2 129 ? -29.044 -6.078  31.732  1   30.94  ? 299 LEU D C   1 
ATOM   7988 O O   . LEU D 2 129 ? -29.644 -5.661  30.729  1   30.31  ? 299 LEU D O   1 
ATOM   7989 C CB  . LEU D 2 129 ? -29.734 -5.076  33.962  1   29.39  ? 299 LEU D CB  1 
ATOM   7990 C CG  . LEU D 2 129 ? -30.936 -4.866  34.892  1   31.81  ? 299 LEU D CG  1 
ATOM   7991 C CD1 . LEU D 2 129 ? -30.671 -3.791  35.948  1   26.62  ? 299 LEU D CD1 1 
ATOM   7992 C CD2 . LEU D 2 129 ? -32.199 -4.561  34.074  1   31.01  ? 299 LEU D CD2 1 
ATOM   7993 N N   . LYS D 2 130 ? -27.734 -6.394  31.762  1   27.39  ? 300 LYS D N   1 
ATOM   7994 C CA  . LYS D 2 130 ? -26.895 -6.205  30.594  1   28.48  ? 300 LYS D CA  1 
ATOM   7995 C C   . LYS D 2 130 ? -27.279 -7.231  29.531  1   28.36  ? 300 LYS D C   1 
ATOM   7996 O O   . LYS D 2 130 ? -27.35  -6.904  28.351  1   27.18  ? 300 LYS D O   1 
ATOM   7997 C CB  . LYS D 2 130 ? -25.381 -6.267  30.859  1   30.71  ? 300 LYS D CB  1 
ATOM   7998 C CG  . LYS D 2 130 ? -24.926 -5.673  32.169  1   35.69  ? 300 LYS D CG  1 
ATOM   7999 C CD  . LYS D 2 130 ? -23.462 -5.249  32.29   1   41.39  ? 300 LYS D CD  1 
ATOM   8000 C CE  . LYS D 2 130 ? -23.001 -5.277  33.748  1   52     ? 300 LYS D CE  1 
ATOM   8001 N NZ  . LYS D 2 130 ? -21.772 -4.507  33.997  1   52.95  ? 300 LYS D NZ  1 
ATOM   8002 N N   . VAL D 2 131 ? -27.504 -8.478  29.957  1   26.99  ? 301 VAL D N   1 
ATOM   8003 C CA  . VAL D 2 131 ? -27.74  -9.56   29.019  1   28.69  ? 301 VAL D CA  1 
ATOM   8004 C C   . VAL D 2 131 ? -29.072 -9.337  28.309  1   33.09  ? 301 VAL D C   1 
ATOM   8005 O O   . VAL D 2 131 ? -29.162 -9.608  27.117  1   33.26  ? 301 VAL D O   1 
ATOM   8006 C CB  . VAL D 2 131 ? -27.655 -10.948 29.673  1   28.15  ? 301 VAL D CB  1 
ATOM   8007 C CG1 . VAL D 2 131 ? -28.308 -12.029 28.815  1   23.34  ? 301 VAL D CG1 1 
ATOM   8008 C CG2 . VAL D 2 131 ? -26.215 -11.313 30.04   1   23.83  ? 301 VAL D CG2 1 
ATOM   8009 N N   . LEU D 2 132 ? -30.076 -8.816  29.035  1   34.79  ? 302 LEU D N   1 
ATOM   8010 C CA  . LEU D 2 132 ? -31.388 -8.535  28.463  1   33.48  ? 302 LEU D CA  1 
ATOM   8011 C C   . LEU D 2 132 ? -31.416 -7.138  27.836  1   33.05  ? 302 LEU D C   1 
ATOM   8012 O O   . LEU D 2 132 ? -32.458 -6.675  27.381  1   31.54  ? 302 LEU D O   1 
ATOM   8013 C CB  . LEU D 2 132 ? -32.454 -8.643  29.549  1   32.74  ? 302 LEU D CB  1 
ATOM   8014 C CG  . LEU D 2 132 ? -32.634 -10.015 30.197  1   37.07  ? 302 LEU D CG  1 
ATOM   8015 C CD1 . LEU D 2 132 ? -33.814 -9.99   31.168  1   37.8   ? 302 LEU D CD1 1 
ATOM   8016 C CD2 . LEU D 2 132 ? -32.848 -11.055 29.12   1   39.51  ? 302 LEU D CD2 1 
ATOM   8017 N N   . ALA D 2 133 ? -30.29  -6.426  27.898  1   30.24  ? 303 ALA D N   1 
ATOM   8018 C CA  . ALA D 2 133 ? -30.217 -5.024  27.504  1   31.42  ? 303 ALA D CA  1 
ATOM   8019 C C   . ALA D 2 133 ? -31.391 -4.178  28.037  1   30.27  ? 303 ALA D C   1 
ATOM   8020 O O   . ALA D 2 133 ? -31.895 -3.297  27.34   1   31.02  ? 303 ALA D O   1 
ATOM   8021 C CB  . ALA D 2 133 ? -30.009 -4.919  26.005  1   28.03  ? 303 ALA D CB  1 
ATOM   8022 N N   . PHE D 2 134 ? -31.782 -4.396  29.302  1   29.57  ? 304 PHE D N   1 
ATOM   8023 C CA  . PHE D 2 134 ? -32.83  -3.633  29.969  1   31.9   ? 304 PHE D CA  1 
ATOM   8024 C C   . PHE D 2 134 ? -34.198 -3.795  29.311  1   29.61  ? 304 PHE D C   1 
ATOM   8025 O O   . PHE D 2 134 ? -35.074 -2.977  29.557  1   29.76  ? 304 PHE D O   1 
ATOM   8026 C CB  . PHE D 2 134 ? -32.529 -2.13   30.015  1   33.46  ? 304 PHE D CB  1 
ATOM   8027 C CG  . PHE D 2 134 ? -31.726 -1.686  31.228  1   38.86  ? 304 PHE D CG  1 
ATOM   8028 C CD1 . PHE D 2 134 ? -30.334 -1.675  31.193  1   33.98  ? 304 PHE D CD1 1 
ATOM   8029 C CD2 . PHE D 2 134 ? -32.375 -1.324  32.414  1   36.99  ? 304 PHE D CD2 1 
ATOM   8030 C CE1 . PHE D 2 134 ? -29.615 -1.275  32.315  1   35.4   ? 304 PHE D CE1 1 
ATOM   8031 C CE2 . PHE D 2 134 ? -31.645 -0.911  33.521  1   35.05  ? 304 PHE D CE2 1 
ATOM   8032 C CZ  . PHE D 2 134 ? -30.267 -0.891  33.474  1   32.88  ? 304 PHE D CZ  1 
ATOM   8033 N N   . ASP D 2 135 ? -34.369 -4.797  28.44   1   34.03  ? 305 ASP D N   1 
ATOM   8034 C CA  . ASP D 2 135 ? -35.654 -5.028  27.788  1   34.65  ? 305 ASP D CA  1 
ATOM   8035 C C   . ASP D 2 135 ? -36.53  -5.833  28.723  1   30     ? 305 ASP D C   1 
ATOM   8036 O O   . ASP D 2 135 ? -36.545 -7.061  28.63   1   32.49  ? 305 ASP D O   1 
ATOM   8037 C CB  . ASP D 2 135 ? -35.506 -5.785  26.483  1   41.03  ? 305 ASP D CB  1 
ATOM   8038 C CG  . ASP D 2 135 ? -34.875 -4.951  25.39   1   55.31  ? 305 ASP D CG  1 
ATOM   8039 O OD1 . ASP D 2 135 ? -34.837 -3.722  25.599  1   67.87  ? 305 ASP D OD1 1 
ATOM   8040 O OD2 . ASP D 2 135 ? -34.363 -5.548  24.407  1   53.47  ? 305 ASP D OD2 1 
ATOM   8041 N N   . LEU D 2 136 ? -37.216 -5.134  29.637  1   26.23  ? 306 LEU D N   1 
ATOM   8042 C CA  . LEU D 2 136 ? -37.866 -5.808  30.747  1   26.17  ? 306 LEU D CA  1 
ATOM   8043 C C   . LEU D 2 136 ? -39.388 -5.832  30.606  1   26.37  ? 306 LEU D C   1 
ATOM   8044 O O   . LEU D 2 136 ? -40.023 -6.643  31.267  1   26.41  ? 306 LEU D O   1 
ATOM   8045 C CB  . LEU D 2 136 ? -37.445 -5.211  32.085  1   28.67  ? 306 LEU D CB  1 
ATOM   8046 C CG  . LEU D 2 136 ? -35.97  -5.356  32.476  1   33.85  ? 306 LEU D CG  1 
ATOM   8047 C CD1 . LEU D 2 136 ? -35.919 -5.274  33.988  1   43.39  ? 306 LEU D CD1 1 
ATOM   8048 C CD2 . LEU D 2 136 ? -35.292 -6.621  31.989  1   27.67  ? 306 LEU D CD2 1 
ATOM   8049 N N   . ALA D 2 137 ? -39.971 -4.956  29.776  1   25.27  ? 307 ALA D N   1 
ATOM   8050 C CA  . ALA D 2 137 ? -41.423 -4.857  29.695  1   28.07  ? 307 ALA D CA  1 
ATOM   8051 C C   . ALA D 2 137 ? -41.957 -5.941  28.755  1   27.07  ? 307 ALA D C   1 
ATOM   8052 O O   . ALA D 2 137 ? -42.437 -5.647  27.658  1   27.38  ? 307 ALA D O   1 
ATOM   8053 C CB  . ALA D 2 137 ? -41.822 -3.451  29.264  1   26.84  ? 307 ALA D CB  1 
ATOM   8054 N N   . ALA D 2 138 ? -41.839 -7.203  29.184  1   24.91  ? 308 ALA D N   1 
ATOM   8055 C CA  . ALA D 2 138 ? -42.164 -8.359  28.361  1   24.03  ? 308 ALA D CA  1 
ATOM   8056 C C   . ALA D 2 138 ? -43.654 -8.613  28.443  1   27.61  ? 308 ALA D C   1 
ATOM   8057 O O   . ALA D 2 138 ? -44.236 -8.51   29.518  1   33.36  ? 308 ALA D O   1 
ATOM   8058 C CB  . ALA D 2 138 ? -41.414 -9.593  28.816  1   21.33  ? 308 ALA D CB  1 
ATOM   8059 N N   . PRO D 2 139 ? -44.32  -8.942  27.317  1   28.41  ? 309 PRO D N   1 
ATOM   8060 C CA  . PRO D 2 139 ? -45.722 -9.345  27.385  1   29.6   ? 309 PRO D CA  1 
ATOM   8061 C C   . PRO D 2 139 ? -45.741 -10.728 28.027  1   29.77  ? 309 PRO D C   1 
ATOM   8062 O O   . PRO D 2 139 ? -44.894 -11.566 27.711  1   31.43  ? 309 PRO D O   1 
ATOM   8063 C CB  . PRO D 2 139 ? -46.225 -9.305  25.924  1   28.1   ? 309 PRO D CB  1 
ATOM   8064 C CG  . PRO D 2 139 ? -45.117 -8.57   25.17   1   29.21  ? 309 PRO D CG  1 
ATOM   8065 C CD  . PRO D 2 139 ? -43.813 -8.857  25.936  1   28.9   ? 309 PRO D CD  1 
ATOM   8066 N N   . THR D 2 140 ? -46.676 -10.915 28.971  1   28.2   ? 310 THR D N   1 
ATOM   8067 C CA  . THR D 2 140 ? -46.859 -12.156 29.711  1   27.99  ? 310 THR D CA  1 
ATOM   8068 C C   . THR D 2 140 ? -48.142 -12.847 29.253  1   31.41  ? 310 THR D C   1 
ATOM   8069 O O   . THR D 2 140 ? -49.024 -12.226 28.655  1   31.01  ? 310 THR D O   1 
ATOM   8070 C CB  . THR D 2 140 ? -46.906 -11.874 31.217  1   25.28  ? 310 THR D CB  1 
ATOM   8071 O OG1 . THR D 2 140 ? -47.981 -10.97  31.472  1   24.51  ? 310 THR D OG1 1 
ATOM   8072 C CG2 . THR D 2 140 ? -45.615 -11.262 31.741  1   25.46  ? 310 THR D CG2 1 
ATOM   8073 N N   . ILE D 2 141 ? -48.268 -14.127 29.617  1   32     ? 311 ILE D N   1 
ATOM   8074 C CA  . ILE D 2 141 ? -49.535 -14.829 29.527  1   31.12  ? 311 ILE D CA  1 
ATOM   8075 C C   . ILE D 2 141 ? -50.626 -13.987 30.186  1   35.69  ? 311 ILE D C   1 
ATOM   8076 O O   . ILE D 2 141 ? -51.698 -13.813 29.611  1   38.58  ? 311 ILE D O   1 
ATOM   8077 C CB  . ILE D 2 141 ? -49.428 -16.217 30.178  1   27.38  ? 311 ILE D CB  1 
ATOM   8078 C CG1 . ILE D 2 141 ? -48.522 -17.133 29.375  1   24.27  ? 311 ILE D CG1 1 
ATOM   8079 C CG2 . ILE D 2 141 ? -50.813 -16.827 30.401  1   25.04  ? 311 ILE D CG2 1 
ATOM   8080 C CD1 . ILE D 2 141 ? -48.154 -18.404 30.119  1   22.79  ? 311 ILE D CD1 1 
ATOM   8081 N N   . ASN D 2 142 ? -50.344 -13.456 31.384  1   36.06  ? 312 ASN D N   1 
ATOM   8082 C CA  . ASN D 2 142 ? -51.354 -12.733 32.147  1   36.47  ? 312 ASN D CA  1 
ATOM   8083 C C   . ASN D 2 142 ? -51.815 -11.474 31.427  1   35.41  ? 312 ASN D C   1 
ATOM   8084 O O   . ASN D 2 142 ? -52.984 -11.125 31.509  1   37.96  ? 312 ASN D O   1 
ATOM   8085 C CB  . ASN D 2 142 ? -50.962 -12.423 33.586  1   37.85  ? 312 ASN D CB  1 
ATOM   8086 C CG  . ASN D 2 142 ? -51.064 -13.667 34.429  1   40.42  ? 312 ASN D CG  1 
ATOM   8087 O OD1 . ASN D 2 142 ? -50.912 -14.778 33.906  1   42.71  ? 312 ASN D OD1 1 
ATOM   8088 N ND2 . ASN D 2 142 ? -51.287 -13.507 35.722  1   42.91  ? 312 ASN D ND2 1 
ATOM   8089 N N   . GLN D 2 143 ? -50.9   -10.787 30.746  1   35.51  ? 313 GLN D N   1 
ATOM   8090 C CA  . GLN D 2 143 ? -51.28  -9.546  30.088  1   34.24  ? 313 GLN D CA  1 
ATOM   8091 C C   . GLN D 2 143 ? -52.339 -9.818  29.024  1   32.28  ? 313 GLN D C   1 
ATOM   8092 O O   . GLN D 2 143 ? -53.154 -8.944  28.749  1   36.97  ? 313 GLN D O   1 
ATOM   8093 C CB  . GLN D 2 143 ? -50.077 -8.839  29.476  1   31.56  ? 313 GLN D CB  1 
ATOM   8094 C CG  . GLN D 2 143 ? -49.352 -7.951  30.469  1   32.25  ? 313 GLN D CG  1 
ATOM   8095 C CD  . GLN D 2 143 ? -48.081 -7.361  29.899  1   31.89  ? 313 GLN D CD  1 
ATOM   8096 O OE1 . GLN D 2 143 ? -48.119 -6.531  28.982  1   30.01  ? 313 GLN D OE1 1 
ATOM   8097 N NE2 . GLN D 2 143 ? -46.947 -7.765  30.463  1   28.96  ? 313 GLN D NE2 1 
ATOM   8098 N N   . PHE D 2 144 ? -52.3   -11.021 28.445  1   28.07  ? 314 PHE D N   1 
ATOM   8099 C CA  . PHE D 2 144 ? -53.224 -11.421 27.402  1   30.69  ? 314 PHE D CA  1 
ATOM   8100 C C   . PHE D 2 144 ? -54.53  -11.936 28.008  1   30.93  ? 314 PHE D C   1 
ATOM   8101 O O   . PHE D 2 144 ? -55.598 -11.619 27.481  1   27.91  ? 314 PHE D O   1 
ATOM   8102 C CB  . PHE D 2 144 ? -52.61  -12.435 26.434  1   28.07  ? 314 PHE D CB  1 
ATOM   8103 C CG  . PHE D 2 144 ? -51.609 -11.831 25.471  1   27.53  ? 314 PHE D CG  1 
ATOM   8104 C CD1 . PHE D 2 144 ? -52.035 -11.048 24.4    1   28.32  ? 314 PHE D CD1 1 
ATOM   8105 C CD2 . PHE D 2 144 ? -50.248 -12.078 25.628  1   25.87  ? 314 PHE D CD2 1 
ATOM   8106 C CE1 . PHE D 2 144 ? -51.101 -10.515 23.52   1   31.18  ? 314 PHE D CE1 1 
ATOM   8107 C CE2 . PHE D 2 144 ? -49.319 -11.536 24.76   1   24.64  ? 314 PHE D CE2 1 
ATOM   8108 C CZ  . PHE D 2 144 ? -49.744 -10.761 23.707  1   29.56  ? 314 PHE D CZ  1 
ATOM   8109 N N   . LEU D 2 145 ? -54.433 -12.722 29.097  1   31.87  ? 315 LEU D N   1 
ATOM   8110 C CA  . LEU D 2 145 ? -55.586 -13.299 29.78   1   31.9   ? 315 LEU D CA  1 
ATOM   8111 C C   . LEU D 2 145 ? -56.573 -12.214 30.195  1   33.23  ? 315 LEU D C   1 
ATOM   8112 O O   . LEU D 2 145 ? -57.748 -12.28  29.809  1   34.77  ? 315 LEU D O   1 
ATOM   8113 C CB  . LEU D 2 145 ? -55.17  -14.125 30.992  1   32.49  ? 315 LEU D CB  1 
ATOM   8114 C CG  . LEU D 2 145 ? -54.601 -15.518 30.718  1   29.57  ? 315 LEU D CG  1 
ATOM   8115 C CD1 . LEU D 2 145 ? -54.4   -16.215 32.064  1   25.24  ? 315 LEU D CD1 1 
ATOM   8116 C CD2 . LEU D 2 145 ? -55.506 -16.312 29.794  1   30.05  ? 315 LEU D CD2 1 
ATOM   8117 N N   . THR D 2 146 ? -56.076 -11.212 30.942  1   31.02  ? 316 THR D N   1 
ATOM   8118 C CA  . THR D 2 146 ? -56.92  -10.142 31.46   1   33.44  ? 316 THR D CA  1 
ATOM   8119 C C   . THR D 2 146 ? -57.693 -9.481  30.312  1   37.88  ? 316 THR D C   1 
ATOM   8120 O O   . THR D 2 146 ? -58.822 -9.021  30.511  1   48.72  ? 316 THR D O   1 
ATOM   8121 C CB  . THR D 2 146 ? -56.123 -9.126  32.287  1   34.06  ? 316 THR D CB  1 
ATOM   8122 O OG1 . THR D 2 146 ? -55.292 -8.39   31.388  1   34.03  ? 316 THR D OG1 1 
ATOM   8123 C CG2 . THR D 2 146 ? -55.305 -9.752  33.411  1   28.72  ? 316 THR D CG2 1 
ATOM   8124 N N   . GLN D 2 147 ? -57.083 -9.437  29.115  1   34.85  ? 317 GLN D N   1 
ATOM   8125 C CA  . GLN D 2 147 ? -57.67  -8.821  27.933  1   33.62  ? 317 GLN D CA  1 
ATOM   8126 C C   . GLN D 2 147 ? -58.742 -9.718  27.318  1   35.41  ? 317 GLN D C   1 
ATOM   8127 O O   . GLN D 2 147 ? -59.734 -9.205  26.79   1   39.22  ? 317 GLN D O   1 
ATOM   8128 C CB  . GLN D 2 147 ? -56.631 -8.565  26.838  1   34.46  ? 317 GLN D CB  1 
ATOM   8129 C CG  . GLN D 2 147 ? -55.833 -7.278  27.017  1   33.63  ? 317 GLN D CG  1 
ATOM   8130 C CD  . GLN D 2 147 ? -55.089 -6.817  25.782  1   36.03  ? 317 GLN D CD  1 
ATOM   8131 O OE1 . GLN D 2 147 ? -53.986 -6.279  25.898  1   40.04  ? 317 GLN D OE1 1 
ATOM   8132 N NE2 . GLN D 2 147 ? -55.699 -6.934  24.603  1   39.03  ? 317 GLN D NE2 1 
ATOM   8133 N N   . TYR D 2 148 ? -58.494 -11.04  27.33   1   34.48  ? 318 TYR D N   1 
ATOM   8134 C CA  . TYR D 2 148 ? -59.423 -12.041 26.823  1   31.61  ? 318 TYR D CA  1 
ATOM   8135 C C   . TYR D 2 148 ? -60.627 -12.165 27.765  1   31.96  ? 318 TYR D C   1 
ATOM   8136 O O   . TYR D 2 148 ? -61.736 -12.49  27.32   1   29.15  ? 318 TYR D O   1 
ATOM   8137 C CB  . TYR D 2 148 ? -58.751 -13.411 26.689  1   30.46  ? 318 TYR D CB  1 
ATOM   8138 C CG  . TYR D 2 148 ? -57.587 -13.544 25.719  1   27.84  ? 318 TYR D CG  1 
ATOM   8139 C CD1 . TYR D 2 148 ? -57.34  -12.616 24.711  1   25.98  ? 318 TYR D CD1 1 
ATOM   8140 C CD2 . TYR D 2 148 ? -56.728 -14.628 25.825  1   26.75  ? 318 TYR D CD2 1 
ATOM   8141 C CE1 . TYR D 2 148 ? -56.263 -12.774 23.848  1   26.69  ? 318 TYR D CE1 1 
ATOM   8142 C CE2 . TYR D 2 148 ? -55.654 -14.798 24.966  1   26.26  ? 318 TYR D CE2 1 
ATOM   8143 C CZ  . TYR D 2 148 ? -55.424 -13.874 23.965  1   27.58  ? 318 TYR D CZ  1 
ATOM   8144 O OH  . TYR D 2 148 ? -54.367 -14.079 23.105  1   32.77  ? 318 TYR D OH  1 
ATOM   8145 N N   . PHE D 2 149 ? -60.392 -11.902 29.062  1   32.58  ? 319 PHE D N   1 
ATOM   8146 C CA  . PHE D 2 149 ? -61.438 -11.933 30.071  1   33.21  ? 319 PHE D CA  1 
ATOM   8147 C C   . PHE D 2 149 ? -62.572 -10.972 29.712  1   36.55  ? 319 PHE D C   1 
ATOM   8148 O O   . PHE D 2 149 ? -63.731 -11.213 30.061  1   40.27  ? 319 PHE D O   1 
ATOM   8149 C CB  . PHE D 2 149 ? -60.862 -11.65  31.458  1   30.18  ? 319 PHE D CB  1 
ATOM   8150 C CG  . PHE D 2 149 ? -59.997 -12.766 32.023  1   33.11  ? 319 PHE D CG  1 
ATOM   8151 C CD1 . PHE D 2 149 ? -59.938 -14.017 31.4    1   34     ? 319 PHE D CD1 1 
ATOM   8152 C CD2 . PHE D 2 149 ? -59.257 -12.569 33.192  1   33.82  ? 319 PHE D CD2 1 
ATOM   8153 C CE1 . PHE D 2 149 ? -59.159 -15.039 31.932  1   35.46  ? 319 PHE D CE1 1 
ATOM   8154 C CE2 . PHE D 2 149 ? -58.459 -13.582 33.719  1   36.28  ? 319 PHE D CE2 1 
ATOM   8155 C CZ  . PHE D 2 149 ? -58.404 -14.814 33.082  1   39.43  ? 319 PHE D CZ  1 
ATOM   8156 N N   . LEU D 2 150 ? -62.233 -9.881  29.02   1   35.46  ? 320 LEU D N   1 
ATOM   8157 C CA  . LEU D 2 150 ? -63.198 -8.831  28.73   1   35.24  ? 320 LEU D CA  1 
ATOM   8158 C C   . LEU D 2 150 ? -64.229 -9.259  27.671  1   33.78  ? 320 LEU D C   1 
ATOM   8159 O O   . LEU D 2 150 ? -65.237 -8.581  27.489  1   34.2   ? 320 LEU D O   1 
ATOM   8160 C CB  . LEU D 2 150 ? -62.419 -7.567  28.344  1   34.99  ? 320 LEU D CB  1 
ATOM   8161 C CG  . LEU D 2 150 ? -61.48  -6.974  29.404  1   33.69  ? 320 LEU D CG  1 
ATOM   8162 C CD1 . LEU D 2 150 ? -60.488 -6.013  28.753  1   31.59  ? 320 LEU D CD1 1 
ATOM   8163 C CD2 . LEU D 2 150 ? -62.209 -6.285  30.553  1   30.52  ? 320 LEU D CD2 1 
ATOM   8164 N N   . HIS D 2 151 ? -63.999 -10.384 26.983  1   32.51  ? 321 HIS D N   1 
ATOM   8165 C CA  . HIS D 2 151 ? -64.946 -10.871 25.996  1   32.34  ? 321 HIS D CA  1 
ATOM   8166 C C   . HIS D 2 151 ? -66.044 -11.708 26.663  1   37.44  ? 321 HIS D C   1 
ATOM   8167 O O   . HIS D 2 151 ? -67.068 -12.034 26.024  1   37.78  ? 321 HIS D O   1 
ATOM   8168 C CB  . HIS D 2 151 ? -64.221 -11.474 24.788  1   34.46  ? 321 HIS D CB  1 
ATOM   8169 C CG  . HIS D 2 151 ? -63.454 -10.464 23.998  1   39.85  ? 321 HIS D CG  1 
ATOM   8170 N ND1 . HIS D 2 151 ? -63.423 -10.454 22.615  1   40.71  ? 321 HIS D ND1 1 
ATOM   8171 C CD2 . HIS D 2 151 ? -62.666 -9.447  24.405  1   39.31  ? 321 HIS D CD2 1 
ATOM   8172 C CE1 . HIS D 2 151 ? -62.657 -9.447  22.206  1   39.8   ? 321 HIS D CE1 1 
ATOM   8173 N NE2 . HIS D 2 151 ? -62.187 -8.829  23.277  1   41.75  ? 321 HIS D NE2 1 
ATOM   8174 N N   . GLN D 2 152 ? -65.857 -11.981 27.97   1   37.64  ? 322 GLN D N   1 
ATOM   8175 C CA  . GLN D 2 152 ? -66.84  -12.715 28.754  1   40.49  ? 322 GLN D CA  1 
ATOM   8176 C C   . GLN D 2 152 ? -68.069 -11.84  28.973  1   44.58  ? 322 GLN D C   1 
ATOM   8177 O O   . GLN D 2 152 ? -67.948 -10.628 29.119  1   51.42  ? 322 GLN D O   1 
ATOM   8178 C CB  . GLN D 2 152 ? -66.344 -13.058 30.15   1   40.74  ? 322 GLN D CB  1 
ATOM   8179 C CG  . GLN D 2 152 ? -65.348 -14.205 30.232  1   41.94  ? 322 GLN D CG  1 
ATOM   8180 C CD  . GLN D 2 152 ? -64.817 -14.301 31.643  1   48.39  ? 322 GLN D CD  1 
ATOM   8181 O OE1 . GLN D 2 152 ? -65.166 -15.217 32.394  1   53.73  ? 322 GLN D OE1 1 
ATOM   8182 N NE2 . GLN D 2 152 ? -64.016 -13.317 32.038  1   43.67  ? 322 GLN D NE2 1 
ATOM   8183 N N   . GLN D 2 153 ? -69.238 -12.481 28.997  1   48.86  ? 323 GLN D N   1 
ATOM   8184 C CA  . GLN D 2 153 ? -70.53  -11.829 29.16   1   49.46  ? 323 GLN D CA  1 
ATOM   8185 C C   . GLN D 2 153 ? -71.467 -12.889 29.734  1   41.97  ? 323 GLN D C   1 
ATOM   8186 O O   . GLN D 2 153 ? -71.983 -13.717 28.984  1   37.6   ? 323 GLN D O   1 
ATOM   8187 C CB  . GLN D 2 153 ? -71.037 -11.099 27.907  1   55.05  ? 323 GLN D CB  1 
ATOM   8188 C CG  . GLN D 2 153 ? -71.322 -11.997 26.707  1   55.46  ? 323 GLN D CG  1 
ATOM   8189 C CD  . GLN D 2 153 ? -71.818 -11.209 25.508  1   58.68  ? 323 GLN D CD  1 
ATOM   8190 O OE1 . GLN D 2 153 ? -71.621 -9.993  25.41   1   58.45  ? 323 GLN D OE1 1 
ATOM   8191 N NE2 . GLN D 2 153 ? -72.46  -11.894 24.568  1   57.88  ? 323 GLN D NE2 1 
ATOM   8192 N N   . PRO D 2 154 ? -71.585 -12.963 31.085  1   37.42  ? 324 PRO D N   1 
ATOM   8193 C CA  . PRO D 2 154 ? -70.914 -12.006 31.968  1   35.85  ? 324 PRO D CA  1 
ATOM   8194 C C   . PRO D 2 154 ? -69.52  -12.524 32.329  1   41.09  ? 324 PRO D C   1 
ATOM   8195 O O   . PRO D 2 154 ? -69.043 -13.514 31.76   1   38.36  ? 324 PRO D O   1 
ATOM   8196 C CB  . PRO D 2 154 ? -71.874 -12.052 33.153  1   32.36  ? 324 PRO D CB  1 
ATOM   8197 C CG  . PRO D 2 154 ? -72.205 -13.526 33.279  1   30.79  ? 324 PRO D CG  1 
ATOM   8198 C CD  . PRO D 2 154 ? -72.289 -14.018 31.84   1   34.42  ? 324 PRO D CD  1 
ATOM   8199 N N   . ALA D 2 155 ? -68.883 -11.847 33.298  1   42.67  ? 325 ALA D N   1 
ATOM   8200 C CA  . ALA D 2 155 ? -67.6   -12.269 33.836  1   38.92  ? 325 ALA D CA  1 
ATOM   8201 C C   . ALA D 2 155 ? -67.835 -13.342 34.899  1   40.65  ? 325 ALA D C   1 
ATOM   8202 O O   . ALA D 2 155 ? -68.673 -13.166 35.787  1   41.94  ? 325 ALA D O   1 
ATOM   8203 C CB  . ALA D 2 155 ? -66.843 -11.083 34.38   1   32.74  ? 325 ALA D CB  1 
ATOM   8204 N N   . ASN D 2 156 ? -67.116 -14.47  34.751  1   38.65  ? 326 ASN D N   1 
ATOM   8205 C CA  . ASN D 2 156 ? -67.127 -15.579 35.694  1   34.65  ? 326 ASN D CA  1 
ATOM   8206 C C   . ASN D 2 156 ? -65.752 -15.608 36.345  1   36.66  ? 326 ASN D C   1 
ATOM   8207 O O   . ASN D 2 156 ? -64.732 -15.595 35.65   1   35.76  ? 326 ASN D O   1 
ATOM   8208 C CB  . ASN D 2 156 ? -67.372 -16.911 34.989  1   33.27  ? 326 ASN D CB  1 
ATOM   8209 C CG  . ASN D 2 156 ? -67.742 -18.044 35.92   1   32.81  ? 326 ASN D CG  1 
ATOM   8210 O OD1 . ASN D 2 156 ? -66.93  -18.49  36.74   1   34.26  ? 326 ASN D OD1 1 
ATOM   8211 N ND2 . ASN D 2 156 ? -68.939 -18.581 35.75   1   28.7   ? 326 ASN D ND2 1 
ATOM   8212 N N   . CYS D 2 157 ? -65.744 -15.667 37.68   1   38.41  ? 327 CYS D N   1 
ATOM   8213 C CA  . CYS D 2 157 ? -64.519 -15.616 38.469  1   36.36  ? 327 CYS D CA  1 
ATOM   8214 C C   . CYS D 2 157 ? -63.862 -16.995 38.559  1   36.58  ? 327 CYS D C   1 
ATOM   8215 O O   . CYS D 2 157 ? -62.67  -17.081 38.842  1   39     ? 327 CYS D O   1 
ATOM   8216 C CB  . CYS D 2 157 ? -64.776 -15.079 39.873  1   36.19  ? 327 CYS D CB  1 
ATOM   8217 S SG  . CYS D 2 157 ? -65.966 -16.099 40.78   1   51.03  ? 327 CYS D SG  1 
ATOM   8218 N N   . LYS D 2 158 ? -64.632 -18.074 38.356  1   36.21  ? 328 LYS D N   1 
ATOM   8219 C CA  . LYS D 2 158 ? -64.032 -19.4   38.304  1   37.21  ? 328 LYS D CA  1 
ATOM   8220 C C   . LYS D 2 158 ? -63.306 -19.612 36.973  1   39.26  ? 328 LYS D C   1 
ATOM   8221 O O   . LYS D 2 158 ? -62.27  -20.27  36.941  1   43.76  ? 328 LYS D O   1 
ATOM   8222 C CB  . LYS D 2 158 ? -65.033 -20.49  38.682  1   39.55  ? 328 LYS D CB  1 
ATOM   8223 C CG  . LYS D 2 158 ? -64.931 -20.93  40.138  1   44.27  ? 328 LYS D CG  1 
ATOM   8224 C CD  . LYS D 2 158 ? -66.286 -21.315 40.722  1   44.75  ? 328 LYS D CD  1 
ATOM   8225 C CE  . LYS D 2 158 ? -66.204 -21.567 42.203  1   51.99  ? 328 LYS D CE  1 
ATOM   8226 N NZ  . LYS D 2 158 ? -66.365 -22.994 42.507  1   51.79  ? 328 LYS D NZ  1 
ATOM   8227 N N   . VAL D 2 159 ? -63.829 -19.039 35.882  1   36.84  ? 329 VAL D N   1 
ATOM   8228 C CA  . VAL D 2 159 ? -63.141 -19.089 34.601  1   33.79  ? 329 VAL D CA  1 
ATOM   8229 C C   . VAL D 2 159 ? -61.833 -18.294 34.711  1   34.82  ? 329 VAL D C   1 
ATOM   8230 O O   . VAL D 2 159 ? -60.781 -18.752 34.268  1   35.16  ? 329 VAL D O   1 
ATOM   8231 C CB  . VAL D 2 159 ? -64.033 -18.636 33.425  1   29.54  ? 329 VAL D CB  1 
ATOM   8232 C CG1 . VAL D 2 159 ? -63.27  -18.516 32.117  1   27.28  ? 329 VAL D CG1 1 
ATOM   8233 C CG2 . VAL D 2 159 ? -65.21  -19.574 33.217  1   30.8   ? 329 VAL D CG2 1 
ATOM   8234 N N   . GLU D 2 160 ? -61.891 -17.113 35.335  1   36.97  ? 330 GLU D N   1 
ATOM   8235 C CA  . GLU D 2 160 ? -60.715 -16.252 35.438  1   37.79  ? 330 GLU D CA  1 
ATOM   8236 C C   . GLU D 2 160 ? -59.606 -16.97  36.2    1   34.6   ? 330 GLU D C   1 
ATOM   8237 O O   . GLU D 2 160 ? -58.5   -17.107 35.678  1   34.84  ? 330 GLU D O   1 
ATOM   8238 C CB  . GLU D 2 160 ? -61.049 -14.885 36.03   1   36.93  ? 330 GLU D CB  1 
ATOM   8239 C CG  . GLU D 2 160 ? -61.939 -14.07  35.097  1   39.04  ? 330 GLU D CG  1 
ATOM   8240 C CD  . GLU D 2 160 ? -62.103 -12.602 35.416  1   42.12  ? 330 GLU D CD  1 
ATOM   8241 O OE1 . GLU D 2 160 ? -61.263 -12.037 36.145  1   48.37  ? 330 GLU D OE1 1 
ATOM   8242 O OE2 . GLU D 2 160 ? -63.076 -12.027 34.907  1   43.22  ? 330 GLU D OE2 1 
ATOM   8243 N N   . SER D 2 161 ? -59.95  -17.486 37.388  1   32.22  ? 331 SER D N   1 
ATOM   8244 C CA  . SER D 2 161 ? -59.016 -18.211 38.239  1   31.85  ? 331 SER D CA  1 
ATOM   8245 C C   . SER D 2 161 ? -58.432 -19.443 37.553  1   31.31  ? 331 SER D C   1 
ATOM   8246 O O   . SER D 2 161 ? -57.231 -19.689 37.666  1   33.59  ? 331 SER D O   1 
ATOM   8247 C CB  . SER D 2 161 ? -59.639 -18.587 39.543  1   33.19  ? 331 SER D CB  1 
ATOM   8248 O OG  . SER D 2 161 ? -59.574 -17.507 40.462  1   36.5   ? 331 SER D OG  1 
ATOM   8249 N N   . LEU D 2 162 ? -59.284 -20.225 36.875  1   29.52  ? 332 LEU D N   1 
ATOM   8250 C CA  . LEU D 2 162 ? -58.858 -21.464 36.242  1   29.38  ? 332 LEU D CA  1 
ATOM   8251 C C   . LEU D 2 162 ? -57.906 -21.168 35.083  1   29.36  ? 332 LEU D C   1 
ATOM   8252 O O   . LEU D 2 162 ? -56.938 -21.903 34.869  1   31.3   ? 332 LEU D O   1 
ATOM   8253 C CB  . LEU D 2 162 ? -60.063 -22.289 35.796  1   27.55  ? 332 LEU D CB  1 
ATOM   8254 C CG  . LEU D 2 162 ? -59.766 -23.693 35.248  1   30.22  ? 332 LEU D CG  1 
ATOM   8255 C CD1 . LEU D 2 162 ? -58.97  -24.534 36.227  1   30.77  ? 332 LEU D CD1 1 
ATOM   8256 C CD2 . LEU D 2 162 ? -61.013 -24.471 34.825  1   31.82  ? 332 LEU D CD2 1 
ATOM   8257 N N   . ALA D 2 163 ? -58.195 -20.091 34.343  1   28.12  ? 333 ALA D N   1 
ATOM   8258 C CA  . ALA D 2 163 ? -57.324 -19.655 33.264  1   30.79  ? 333 ALA D CA  1 
ATOM   8259 C C   . ALA D 2 163 ? -55.954 -19.199 33.801  1   30.79  ? 333 ALA D C   1 
ATOM   8260 O O   . ALA D 2 163 ? -54.928 -19.513 33.212  1   29.26  ? 333 ALA D O   1 
ATOM   8261 C CB  . ALA D 2 163 ? -58.031 -18.61  32.42   1   29.9   ? 333 ALA D CB  1 
ATOM   8262 N N   . MET D 2 164 ? -55.936 -18.496 34.946  1   33.96  ? 334 MET D N   1 
ATOM   8263 C CA  . MET D 2 164 ? -54.7   -18.066 35.596  1   33.72  ? 334 MET D CA  1 
ATOM   8264 C C   . MET D 2 164 ? -53.888 -19.291 36.026  1   35.92  ? 334 MET D C   1 
ATOM   8265 O O   . MET D 2 164 ? -52.66  -19.308 35.872  1   35.42  ? 334 MET D O   1 
ATOM   8266 C CB  . MET D 2 164 ? -54.956 -17.149 36.806  1   32.2   ? 334 MET D CB  1 
ATOM   8267 C CG  . MET D 2 164 ? -55.365 -15.707 36.476  1   36.3   ? 334 MET D CG  1 
ATOM   8268 S SD  . MET D 2 164 ? -54.224 -14.737 35.449  1   41.31  ? 334 MET D SD  1 
ATOM   8269 C CE  . MET D 2 164 ? -54.844 -13.076 35.755  1   51.48  ? 334 MET D CE  1 
ATOM   8270 N N   . PHE D 2 165 ? -54.591 -20.325 36.526  1   32.48  ? 335 PHE D N   1 
ATOM   8271 C CA  . PHE D 2 165 ? -53.963 -21.518 37.079  1   32.17  ? 335 PHE D CA  1 
ATOM   8272 C C   . PHE D 2 165 ? -53.308 -22.353 35.981  1   34.69  ? 335 PHE D C   1 
ATOM   8273 O O   . PHE D 2 165 ? -52.145 -22.739 36.102  1   34.24  ? 335 PHE D O   1 
ATOM   8274 C CB  . PHE D 2 165 ? -55.02  -22.342 37.814  1   31.01  ? 335 PHE D CB  1 
ATOM   8275 C CG  . PHE D 2 165 ? -54.628 -23.776 38.123  1   30.69  ? 335 PHE D CG  1 
ATOM   8276 C CD1 . PHE D 2 165 ? -53.631 -24.071 39.042  1   31.54  ? 335 PHE D CD1 1 
ATOM   8277 C CD2 . PHE D 2 165 ? -55.306 -24.836 37.533  1   34.11  ? 335 PHE D CD2 1 
ATOM   8278 C CE1 . PHE D 2 165 ? -53.311 -25.389 39.348  1   32.73  ? 335 PHE D CE1 1 
ATOM   8279 C CE2 . PHE D 2 165 ? -54.992 -26.155 37.856  1   32.81  ? 335 PHE D CE2 1 
ATOM   8280 C CZ  . PHE D 2 165 ? -53.988 -26.433 38.752  1   30.85  ? 335 PHE D CZ  1 
ATOM   8281 N N   . LEU D 2 166 ? -54.081 -22.657 34.928  1   35.69  ? 336 LEU D N   1 
ATOM   8282 C CA  . LEU D 2 166 ? -53.562 -23.395 33.784  1   32.76  ? 336 LEU D CA  1 
ATOM   8283 C C   . LEU D 2 166 ? -52.367 -22.629 33.223  1   34.24  ? 336 LEU D C   1 
ATOM   8284 O O   . LEU D 2 166 ? -51.369 -23.236 32.83   1   36.61  ? 336 LEU D O   1 
ATOM   8285 C CB  . LEU D 2 166 ? -54.629 -23.622 32.711  1   28.5   ? 336 LEU D CB  1 
ATOM   8286 C CG  . LEU D 2 166 ? -55.842 -24.457 33.129  1   29.79  ? 336 LEU D CG  1 
ATOM   8287 C CD1 . LEU D 2 166 ? -56.895 -24.495 32.029  1   31.93  ? 336 LEU D CD1 1 
ATOM   8288 C CD2 . LEU D 2 166 ? -55.476 -25.868 33.56   1   27.97  ? 336 LEU D CD2 1 
ATOM   8289 N N   . GLY D 2 167 ? -52.493 -21.294 33.177  1   31.29  ? 337 GLY D N   1 
ATOM   8290 C CA  . GLY D 2 167 ? -51.427 -20.432 32.687  1   33.84  ? 337 GLY D CA  1 
ATOM   8291 C C   . GLY D 2 167 ? -50.119 -20.583 33.468  1   31.96  ? 337 GLY D C   1 
ATOM   8292 O O   . GLY D 2 167 ? -49.053 -20.703 32.871  1   33.14  ? 337 GLY D O   1 
ATOM   8293 N N   . GLU D 2 168 ? -50.215 -20.573 34.802  1   31.77  ? 338 GLU D N   1 
ATOM   8294 C CA  . GLU D 2 168 ? -49.06  -20.714 35.677  1   30.35  ? 338 GLU D CA  1 
ATOM   8295 C C   . GLU D 2 168 ? -48.426 -22.1   35.552  1   31.73  ? 338 GLU D C   1 
ATOM   8296 O O   . GLU D 2 168 ? -47.197 -22.202 35.58   1   33.15  ? 338 GLU D O   1 
ATOM   8297 C CB  . GLU D 2 168 ? -49.414 -20.436 37.136  1   29.21  ? 338 GLU D CB  1 
ATOM   8298 C CG  . GLU D 2 168 ? -49.472 -18.955 37.484  1   31.04  ? 338 GLU D CG  1 
ATOM   8299 C CD  . GLU D 2 168 ? -49.517 -18.734 38.983  1   35.31  ? 338 GLU D CD  1 
ATOM   8300 O OE1 . GLU D 2 168 ? -48.84  -19.5   39.728  1   34.56  ? 338 GLU D OE1 1 
ATOM   8301 O OE2 . GLU D 2 168 ? -50.193 -17.759 39.39   1   36.87  ? 338 GLU D OE2 1 
ATOM   8302 N N   . LEU D 2 169 ? -49.246 -23.156 35.409  1   30.67  ? 339 LEU D N   1 
ATOM   8303 C CA  . LEU D 2 169 ? -48.741 -24.519 35.273  1   30.25  ? 339 LEU D CA  1 
ATOM   8304 C C   . LEU D 2 169 ? -47.745 -24.633 34.122  1   31.31  ? 339 LEU D C   1 
ATOM   8305 O O   . LEU D 2 169 ? -46.75  -25.338 34.261  1   37.91  ? 339 LEU D O   1 
ATOM   8306 C CB  . LEU D 2 169 ? -49.863 -25.536 35.083  1   30.77  ? 339 LEU D CB  1 
ATOM   8307 C CG  . LEU D 2 169 ? -50.696 -25.902 36.317  1   29.37  ? 339 LEU D CG  1 
ATOM   8308 C CD1 . LEU D 2 169 ? -51.779 -26.875 35.899  1   29.98  ? 339 LEU D CD1 1 
ATOM   8309 C CD2 . LEU D 2 169 ? -49.86  -26.506 37.426  1   27.16  ? 339 LEU D CD2 1 
ATOM   8310 N N   . SER D 2 170 ? -48.031 -23.947 33.005  1   29.87  ? 340 SER D N   1 
ATOM   8311 C CA  . SER D 2 170 ? -47.205 -23.934 31.807  1   29.89  ? 340 SER D CA  1 
ATOM   8312 C C   . SER D 2 170 ? -45.818 -23.338 32.064  1   32.91  ? 340 SER D C   1 
ATOM   8313 O O   . SER D 2 170 ? -44.871 -23.67  31.355  1   36.54  ? 340 SER D O   1 
ATOM   8314 C CB  . SER D 2 170 ? -47.897 -23.223 30.664  1   29.6   ? 340 SER D CB  1 
ATOM   8315 O OG  . SER D 2 170 ? -47.755 -21.81  30.753  1   29.51  ? 340 SER D OG  1 
ATOM   8316 N N   . LEU D 2 171 ? -45.701 -22.43  33.045  1   33.5   ? 341 LEU D N   1 
ATOM   8317 C CA  . LEU D 2 171 ? -44.434 -21.811 33.422  1   28.95  ? 341 LEU D CA  1 
ATOM   8318 C C   . LEU D 2 171 ? -43.399 -22.879 33.781  1   29.35  ? 341 LEU D C   1 
ATOM   8319 O O   . LEU D 2 171 ? -42.215 -22.692 33.518  1   28.97  ? 341 LEU D O   1 
ATOM   8320 C CB  . LEU D 2 171 ? -44.649 -20.863 34.606  1   25.64  ? 341 LEU D CB  1 
ATOM   8321 C CG  . LEU D 2 171 ? -45.443 -19.582 34.333  1   21.52  ? 341 LEU D CG  1 
ATOM   8322 C CD1 . LEU D 2 171 ? -45.405 -18.659 35.514  1   19.91  ? 341 LEU D CD1 1 
ATOM   8323 C CD2 . LEU D 2 171 ? -44.922 -18.831 33.101  1   23.56  ? 341 LEU D CD2 1 
ATOM   8324 N N   . ILE D 2 172 ? -43.869 -24.001 34.349  1   26.84  ? 342 ILE D N   1 
ATOM   8325 C CA  . ILE D 2 172 ? -43.044 -24.974 35.047  1   27.14  ? 342 ILE D CA  1 
ATOM   8326 C C   . ILE D 2 172 ? -42.25  -25.826 34.054  1   30.57  ? 342 ILE D C   1 
ATOM   8327 O O   . ILE D 2 172 ? -41.102 -26.202 34.345  1   30.51  ? 342 ILE D O   1 
ATOM   8328 C CB  . ILE D 2 172 ? -43.943 -25.834 35.961  1   25.85  ? 342 ILE D CB  1 
ATOM   8329 C CG1 . ILE D 2 172 ? -44.58  -25.015 37.076  1   23.73  ? 342 ILE D CG1 1 
ATOM   8330 C CG2 . ILE D 2 172 ? -43.203 -27.052 36.513  1   26.76  ? 342 ILE D CG2 1 
ATOM   8331 C CD1 . ILE D 2 172 ? -43.607 -24.577 38.158  1   23.14  ? 342 ILE D CD1 1 
ATOM   8332 N N   . ASP D 2 173 ? -42.886 -26.137 32.907  1   29.21  ? 343 ASP D N   1 
ATOM   8333 C CA  . ASP D 2 173 ? -42.427 -27.144 31.961  1   30.07  ? 343 ASP D CA  1 
ATOM   8334 C C   . ASP D 2 173 ? -41.979 -26.499 30.653  1   31.1   ? 343 ASP D C   1 
ATOM   8335 O O   . ASP D 2 173 ? -42.799 -26.231 29.783  1   34.68  ? 343 ASP D O   1 
ATOM   8336 C CB  . ASP D 2 173 ? -43.52  -28.171 31.717  1   31.65  ? 343 ASP D CB  1 
ATOM   8337 C CG  . ASP D 2 173 ? -43.941 -28.882 32.986  1   34.27  ? 343 ASP D CG  1 
ATOM   8338 O OD1 . ASP D 2 173 ? -43.029 -29.384 33.688  1   35.64  ? 343 ASP D OD1 1 
ATOM   8339 O OD2 . ASP D 2 173 ? -45.154 -28.872 33.277  1   37.24  ? 343 ASP D OD2 1 
ATOM   8340 N N   . ALA D 2 174 ? -40.668 -26.318 30.494  1   29.39  ? 344 ALA D N   1 
ATOM   8341 C CA  . ALA D 2 174 ? -40.095 -25.708 29.302  1   30.94  ? 344 ALA D CA  1 
ATOM   8342 C C   . ALA D 2 174 ? -40.467 -26.532 28.07   1   32.57  ? 344 ALA D C   1 
ATOM   8343 O O   . ALA D 2 174 ? -40.678 -25.999 26.981  1   28.95  ? 344 ALA D O   1 
ATOM   8344 C CB  . ALA D 2 174 ? -38.588 -25.635 29.444  1   30.45  ? 344 ALA D CB  1 
ATOM   8345 N N   . ASP D 2 175 ? -40.484 -27.854 28.261  1   33.04  ? 345 ASP D N   1 
ATOM   8346 C CA  . ASP D 2 175 ? -40.988 -28.773 27.266  1   33.96  ? 345 ASP D CA  1 
ATOM   8347 C C   . ASP D 2 175 ? -42.362 -29.222 27.748  1   31.38  ? 345 ASP D C   1 
ATOM   8348 O O   . ASP D 2 175 ? -42.438 -29.922 28.747  1   29.02  ? 345 ASP D O   1 
ATOM   8349 C CB  . ASP D 2 175 ? -40.029 -29.939 27.061  1   38.5   ? 345 ASP D CB  1 
ATOM   8350 C CG  . ASP D 2 175 ? -40.504 -31.002 26.078  1   42.84  ? 345 ASP D CG  1 
ATOM   8351 O OD1 . ASP D 2 175 ? -41.385 -30.691 25.244  1   47.54  ? 345 ASP D OD1 1 
ATOM   8352 O OD2 . ASP D 2 175 ? -40.013 -32.143 26.172  1   40.62  ? 345 ASP D OD2 1 
ATOM   8353 N N   . PRO D 2 176 ? -43.478 -28.889 27.052  1   32.11  ? 346 PRO D N   1 
ATOM   8354 C CA  . PRO D 2 176 ? -43.435 -28.228 25.74   1   31.31  ? 346 PRO D CA  1 
ATOM   8355 C C   . PRO D 2 176 ? -43.497 -26.702 25.594  1   31.44  ? 346 PRO D C   1 
ATOM   8356 O O   . PRO D 2 176 ? -43.265 -26.192 24.494  1   34.76  ? 346 PRO D O   1 
ATOM   8357 C CB  . PRO D 2 176 ? -44.672 -28.881 25.089  1   30.95  ? 346 PRO D CB  1 
ATOM   8358 C CG  . PRO D 2 176 ? -45.676 -28.983 26.22   1   30.97  ? 346 PRO D CG  1 
ATOM   8359 C CD  . PRO D 2 176 ? -44.847 -29.236 27.468  1   28.94  ? 346 PRO D CD  1 
ATOM   8360 N N   . TYR D 2 177 ? -43.785 -25.973 26.681  1   27.14  ? 347 TYR D N   1 
ATOM   8361 C CA  . TYR D 2 177 ? -44.364 -24.638 26.581  1   26.45  ? 347 TYR D CA  1 
ATOM   8362 C C   . TYR D 2 177 ? -43.443 -23.554 26.003  1   30.25  ? 347 TYR D C   1 
ATOM   8363 O O   . TYR D 2 177 ? -43.932 -22.548 25.484  1   30.76  ? 347 TYR D O   1 
ATOM   8364 C CB  . TYR D 2 177 ? -45.069 -24.266 27.884  1   26.29  ? 347 TYR D CB  1 
ATOM   8365 C CG  . TYR D 2 177 ? -46.194 -25.246 28.164  1   29.03  ? 347 TYR D CG  1 
ATOM   8366 C CD1 . TYR D 2 177 ? -47.353 -25.25  27.385  1   29.24  ? 347 TYR D CD1 1 
ATOM   8367 C CD2 . TYR D 2 177 ? -46.079 -26.2   29.168  1   29.79  ? 347 TYR D CD2 1 
ATOM   8368 C CE1 . TYR D 2 177 ? -48.366 -26.172 27.602  1   28.92  ? 347 TYR D CE1 1 
ATOM   8369 C CE2 . TYR D 2 177 ? -47.092 -27.119 29.397  1   30.44  ? 347 TYR D CE2 1 
ATOM   8370 C CZ  . TYR D 2 177 ? -48.237 -27.11  28.613  1   28.29  ? 347 TYR D CZ  1 
ATOM   8371 O OH  . TYR D 2 177 ? -49.233 -28.013 28.845  1   26.22  ? 347 TYR D OH  1 
ATOM   8372 N N   . LEU D 2 178 ? -42.121 -23.726 26.062  1   31.72  ? 348 LEU D N   1 
ATOM   8373 C CA  . LEU D 2 178 ? -41.242 -22.789 25.367  1   35.1   ? 348 LEU D CA  1 
ATOM   8374 C C   . LEU D 2 178 ? -41.58  -22.683 23.872  1   33.76  ? 348 LEU D C   1 
ATOM   8375 O O   . LEU D 2 178 ? -41.252 -21.68  23.241  1   32.84  ? 348 LEU D O   1 
ATOM   8376 C CB  . LEU D 2 178 ? -39.76  -23.114 25.547  1   34.46  ? 348 LEU D CB  1 
ATOM   8377 C CG  . LEU D 2 178 ? -39.117 -22.771 26.891  1   36.35  ? 348 LEU D CG  1 
ATOM   8378 C CD1 . LEU D 2 178 ? -37.664 -23.207 26.815  1   39.38  ? 348 LEU D CD1 1 
ATOM   8379 C CD2 . LEU D 2 178 ? -39.173 -21.287 27.151  1   37     ? 348 LEU D CD2 1 
ATOM   8380 N N   . LYS D 2 179 ? -42.229 -23.692 23.282  1   32.71  ? 349 LYS D N   1 
ATOM   8381 C CA  . LYS D 2 179 ? -42.548 -23.564 21.866  1   34.43  ? 349 LYS D CA  1 
ATOM   8382 C C   . LYS D 2 179 ? -43.776 -22.683 21.605  1   34.88  ? 349 LYS D C   1 
ATOM   8383 O O   . LYS D 2 179 ? -43.998 -22.291 20.469  1   40     ? 349 LYS D O   1 
ATOM   8384 C CB  . LYS D 2 179 ? -42.541 -24.873 21.082  1   30.37  ? 349 LYS D CB  1 
ATOM   8385 C CG  . LYS D 2 179 ? -43.658 -25.831 21.39   1   34.78  ? 349 LYS D CG  1 
ATOM   8386 C CD  . LYS D 2 179 ? -43.426 -27.235 20.811  1   36.03  ? 349 LYS D CD  1 
ATOM   8387 C CE  . LYS D 2 179 ? -44.147 -28.312 21.569  1   35.31  ? 349 LYS D CE  1 
ATOM   8388 N NZ  . LYS D 2 179 ? -44.224 -29.582 20.838  1   37.62  ? 349 LYS D NZ  1 
ATOM   8389 N N   . TYR D 2 180 ? -44.557 -22.331 22.632  1   33.86  ? 350 TYR D N   1 
ATOM   8390 C CA  . TYR D 2 180 ? -45.745 -21.511 22.414  1   32.85  ? 350 TYR D CA  1 
ATOM   8391 C C   . TYR D 2 180 ? -45.53  -20.082 22.911  1   31.87  ? 350 TYR D C   1 
ATOM   8392 O O   . TYR D 2 180 ? -44.873 -19.86  23.923  1   33.42  ? 350 TYR D O   1 
ATOM   8393 C CB  . TYR D 2 180 ? -46.991 -22.137 23.045  1   31.58  ? 350 TYR D CB  1 
ATOM   8394 C CG  . TYR D 2 180 ? -47.232 -23.583 22.643  1   30.23  ? 350 TYR D CG  1 
ATOM   8395 C CD1 . TYR D 2 180 ? -47.576 -23.891 21.33   1   31.01  ? 350 TYR D CD1 1 
ATOM   8396 C CD2 . TYR D 2 180 ? -47.119 -24.621 23.569  1   26.46  ? 350 TYR D CD2 1 
ATOM   8397 C CE1 . TYR D 2 180 ? -47.811 -25.2   20.947  1   32.23  ? 350 TYR D CE1 1 
ATOM   8398 C CE2 . TYR D 2 180 ? -47.357 -25.93  23.197  1   27.49  ? 350 TYR D CE2 1 
ATOM   8399 C CZ  . TYR D 2 180 ? -47.695 -26.212 21.886  1   30.93  ? 350 TYR D CZ  1 
ATOM   8400 O OH  . TYR D 2 180 ? -47.909 -27.495 21.506  1   36.06  ? 350 TYR D OH  1 
ATOM   8401 N N   . LEU D 2 181 ? -46.081 -19.123 22.163  1   29.5   ? 351 LEU D N   1 
ATOM   8402 C CA  . LEU D 2 181 ? -46.039 -17.712 22.512  1   30.73  ? 351 LEU D CA  1 
ATOM   8403 C C   . LEU D 2 181 ? -47.023 -17.455 23.646  1   32.43  ? 351 LEU D C   1 
ATOM   8404 O O   . LEU D 2 181 ? -48.003 -18.173 23.788  1   34.56  ? 351 LEU D O   1 
ATOM   8405 C CB  . LEU D 2 181 ? -46.364 -16.826 21.31   1   29.54  ? 351 LEU D CB  1 
ATOM   8406 C CG  . LEU D 2 181 ? -45.296 -16.715 20.22   1   29.3   ? 351 LEU D CG  1 
ATOM   8407 C CD1 . LEU D 2 181 ? -45.77  -15.807 19.102  1   27.3   ? 351 LEU D CD1 1 
ATOM   8408 C CD2 . LEU D 2 181 ? -44.033 -16.159 20.844  1   30.14  ? 351 LEU D CD2 1 
ATOM   8409 N N   . PRO D 2 182 ? -46.774 -16.45  24.511  1   32.87  ? 352 PRO D N   1 
ATOM   8410 C CA  . PRO D 2 182 ? -47.664 -16.18  25.642  1   31.88  ? 352 PRO D CA  1 
ATOM   8411 C C   . PRO D 2 182 ? -49.127 -16.042 25.23   1   35.81  ? 352 PRO D C   1 
ATOM   8412 O O   . PRO D 2 182 ? -50.006 -16.588 25.896  1   38.49  ? 352 PRO D O   1 
ATOM   8413 C CB  . PRO D 2 182 ? -47.106 -14.877 26.23   1   32.19  ? 352 PRO D CB  1 
ATOM   8414 C CG  . PRO D 2 182 ? -45.635 -14.911 25.853  1   33.64  ? 352 PRO D CG  1 
ATOM   8415 C CD  . PRO D 2 182 ? -45.577 -15.593 24.487  1   32.53  ? 352 PRO D CD  1 
ATOM   8416 N N   . SER D 2 183 ? -49.378 -15.306 24.138  1   31.12  ? 353 SER D N   1 
ATOM   8417 C CA  . SER D 2 183 ? -50.733 -15.075 23.664  1   28.71  ? 353 SER D CA  1 
ATOM   8418 C C   . SER D 2 183 ? -51.441 -16.382 23.313  1   29.33  ? 353 SER D C   1 
ATOM   8419 O O   . SER D 2 183 ? -52.667 -16.453 23.42   1   29.1   ? 353 SER D O   1 
ATOM   8420 C CB  . SER D 2 183 ? -50.739 -14.161 22.491  1   29.25  ? 353 SER D CB  1 
ATOM   8421 O OG  . SER D 2 183 ? -50.052 -14.804 21.439  1   33.66  ? 353 SER D OG  1 
ATOM   8422 N N   . VAL D 2 184 ? -50.668 -17.383 22.858  1   27.46  ? 354 VAL D N   1 
ATOM   8423 C CA  . VAL D 2 184 ? -51.192 -18.685 22.455  1   25.6   ? 354 VAL D CA  1 
ATOM   8424 C C   . VAL D 2 184 ? -51.519 -19.516 23.695  1   24.58  ? 354 VAL D C   1 
ATOM   8425 O O   . VAL D 2 184 ? -52.629 -20.033 23.814  1   25.64  ? 354 VAL D O   1 
ATOM   8426 C CB  . VAL D 2 184 ? -50.275 -19.456 21.481  1   25.66  ? 354 VAL D CB  1 
ATOM   8427 C CG1 . VAL D 2 184 ? -50.729 -20.887 21.256  1   24.34  ? 354 VAL D CG1 1 
ATOM   8428 C CG2 . VAL D 2 184 ? -50.132 -18.756 20.14   1   26.82  ? 354 VAL D CG2 1 
ATOM   8429 N N   . ILE D 2 185 ? -50.559 -19.636 24.619  1   24.31  ? 355 ILE D N   1 
ATOM   8430 C CA  . ILE D 2 185 ? -50.826 -20.323 25.872  1   24.57  ? 355 ILE D CA  1 
ATOM   8431 C C   . ILE D 2 185 ? -52.027 -19.688 26.557  1   24.84  ? 355 ILE D C   1 
ATOM   8432 O O   . ILE D 2 185 ? -52.886 -20.412 27.031  1   27.49  ? 355 ILE D O   1 
ATOM   8433 C CB  . ILE D 2 185 ? -49.598 -20.354 26.792  1   22.69  ? 355 ILE D CB  1 
ATOM   8434 C CG1 . ILE D 2 185 ? -48.525 -21.255 26.205  1   23.23  ? 355 ILE D CG1 1 
ATOM   8435 C CG2 . ILE D 2 185 ? -49.992 -20.798 28.199  1   21.31  ? 355 ILE D CG2 1 
ATOM   8436 C CD1 . ILE D 2 185 ? -47.151 -20.994 26.788  1   23.89  ? 355 ILE D CD1 1 
ATOM   8437 N N   . ALA D 2 186 ? -52.085 -18.347 26.579  1   25.96  ? 356 ALA D N   1 
ATOM   8438 C CA  . ALA D 2 186 ? -53.176 -17.625 27.219  1   25.72  ? 356 ALA D CA  1 
ATOM   8439 C C   . ALA D 2 186 ? -54.526 -18.03  26.622  1   29.38  ? 356 ALA D C   1 
ATOM   8440 O O   . ALA D 2 186 ? -55.458 -18.358 27.366  1   28.97  ? 356 ALA D O   1 
ATOM   8441 C CB  . ALA D 2 186 ? -52.97  -16.153 27.077  1   22.8   ? 356 ALA D CB  1 
ATOM   8442 N N   . ALA D 2 187 ? -54.607 -18.018 25.279  1   29.03  ? 357 ALA D N   1 
ATOM   8443 C CA  . ALA D 2 187 ? -55.807 -18.423 24.557  1   30.37  ? 357 ALA D CA  1 
ATOM   8444 C C   . ALA D 2 187 ? -56.192 -19.857 24.926  1   31.2   ? 357 ALA D C   1 
ATOM   8445 O O   . ALA D 2 187 ? -57.345 -20.109 25.234  1   32.93  ? 357 ALA D O   1 
ATOM   8446 C CB  . ALA D 2 187 ? -55.602 -18.261 23.062  1   29.88  ? 357 ALA D CB  1 
ATOM   8447 N N   . ALA D 2 188 ? -55.226 -20.789 24.903  1   32.81  ? 358 ALA D N   1 
ATOM   8448 C CA  . ALA D 2 188 ? -55.471 -22.178 25.256  1   34.19  ? 358 ALA D CA  1 
ATOM   8449 C C   . ALA D 2 188 ? -56.057 -22.269 26.662  1   35.4   ? 358 ALA D C   1 
ATOM   8450 O O   . ALA D 2 188 ? -57.129 -22.843 26.851  1   40.79  ? 358 ALA D O   1 
ATOM   8451 C CB  . ALA D 2 188 ? -54.198 -22.979 25.135  1   33.3   ? 358 ALA D CB  1 
ATOM   8452 N N   . ALA D 2 189 ? -55.363 -21.661 27.626  1   31.86  ? 359 ALA D N   1 
ATOM   8453 C CA  . ALA D 2 189 ? -55.739 -21.684 29.029  1   32.59  ? 359 ALA D CA  1 
ATOM   8454 C C   . ALA D 2 189 ? -57.148 -21.124 29.238  1   35     ? 359 ALA D C   1 
ATOM   8455 O O   . ALA D 2 189 ? -57.875 -21.584 30.121  1   33.43  ? 359 ALA D O   1 
ATOM   8456 C CB  . ALA D 2 189 ? -54.713 -20.9   29.828  1   31.24  ? 359 ALA D CB  1 
ATOM   8457 N N   . PHE D 2 190 ? -57.508 -20.1   28.451  1   33.7   ? 360 PHE D N   1 
ATOM   8458 C CA  . PHE D 2 190 ? -58.798 -19.443 28.573  1   31.97  ? 360 PHE D CA  1 
ATOM   8459 C C   . PHE D 2 190 ? -59.909 -20.32  27.995  1   32.83  ? 360 PHE D C   1 
ATOM   8460 O O   . PHE D 2 190 ? -60.964 -20.464 28.607  1   31.68  ? 360 PHE D O   1 
ATOM   8461 C CB  . PHE D 2 190 ? -58.782 -18.072 27.898  1   30.86  ? 360 PHE D CB  1 
ATOM   8462 C CG  . PHE D 2 190 ? -60.13  -17.372 27.912  1   31.92  ? 360 PHE D CG  1 
ATOM   8463 C CD1 . PHE D 2 190 ? -60.716 -16.995 29.113  1   32.4   ? 360 PHE D CD1 1 
ATOM   8464 C CD2 . PHE D 2 190 ? -60.798 -17.077 26.73   1   34.23  ? 360 PHE D CD2 1 
ATOM   8465 C CE1 . PHE D 2 190 ? -61.942 -16.354 29.138  1   31.98  ? 360 PHE D CE1 1 
ATOM   8466 C CE2 . PHE D 2 190 ? -62.02  -16.423 26.764  1   34.68  ? 360 PHE D CE2 1 
ATOM   8467 C CZ  . PHE D 2 190 ? -62.591 -16.066 27.965  1   34.04  ? 360 PHE D CZ  1 
ATOM   8468 N N   . HIS D 2 191 ? -59.672 -20.89  26.806  1   34.86  ? 361 HIS D N   1 
ATOM   8469 C CA  . HIS D 2 191 ? -60.625 -21.82  26.225  1   36.59  ? 361 HIS D CA  1 
ATOM   8470 C C   . HIS D 2 191 ? -60.848 -22.963 27.208  1   36.51  ? 361 HIS D C   1 
ATOM   8471 O O   . HIS D 2 191 ? -61.987 -23.252 27.576  1   38.75  ? 361 HIS D O   1 
ATOM   8472 C CB  . HIS D 2 191 ? -60.166 -22.38  24.872  1   37.13  ? 361 HIS D CB  1 
ATOM   8473 C CG  . HIS D 2 191 ? -61.028 -23.534 24.456  1   39.64  ? 361 HIS D CG  1 
ATOM   8474 N ND1 . HIS D 2 191 ? -62.053 -23.434 23.54   1   40.41  ? 361 HIS D ND1 1 
ATOM   8475 C CD2 . HIS D 2 191 ? -61.05  -24.805 24.881  1   38.69  ? 361 HIS D CD2 1 
ATOM   8476 C CE1 . HIS D 2 191 ? -62.643 -24.609 23.4    1   37.78  ? 361 HIS D CE1 1 
ATOM   8477 N NE2 . HIS D 2 191 ? -62.05  -25.451 24.205  1   37.71  ? 361 HIS D NE2 1 
ATOM   8478 N N   . LEU D 2 192 ? -59.741 -23.598 27.614  1   33.85  ? 362 LEU D N   1 
ATOM   8479 C CA  . LEU D 2 192 ? -59.789 -24.796 28.428  1   31.38  ? 362 LEU D CA  1 
ATOM   8480 C C   . LEU D 2 192 ? -60.511 -24.539 29.751  1   31.35  ? 362 LEU D C   1 
ATOM   8481 O O   . LEU D 2 192 ? -61.213 -25.431 30.244  1   29.44  ? 362 LEU D O   1 
ATOM   8482 C CB  . LEU D 2 192 ? -58.356 -25.273 28.62   1   31.13  ? 362 LEU D CB  1 
ATOM   8483 C CG  . LEU D 2 192 ? -58.173 -26.584 29.388  1   33.33  ? 362 LEU D CG  1 
ATOM   8484 C CD1 . LEU D 2 192 ? -59.11  -27.706 28.915  1   30.59  ? 362 LEU D CD1 1 
ATOM   8485 C CD2 . LEU D 2 192 ? -56.706 -27.008 29.322  1   32.88  ? 362 LEU D CD2 1 
ATOM   8486 N N   . ALA D 2 193 ? -60.383 -23.309 30.276  1   29.47  ? 363 ALA D N   1 
ATOM   8487 C CA  . ALA D 2 193 ? -61.006 -22.903 31.53   1   32.05  ? 363 ALA D CA  1 
ATOM   8488 C C   . ALA D 2 193 ? -62.489 -22.566 31.357  1   35.46  ? 363 ALA D C   1 
ATOM   8489 O O   . ALA D 2 193 ? -63.304 -22.849 32.238  1   34.21  ? 363 ALA D O   1 
ATOM   8490 C CB  . ALA D 2 193 ? -60.28  -21.718 32.11   1   29.98  ? 363 ALA D CB  1 
ATOM   8491 N N   . LEU D 2 194 ? -62.813 -21.904 30.238  1   37.24  ? 364 LEU D N   1 
ATOM   8492 C CA  . LEU D 2 194 ? -64.174 -21.529 29.896  1   38.01  ? 364 LEU D CA  1 
ATOM   8493 C C   . LEU D 2 194 ? -65.001 -22.789 29.604  1   42.89  ? 364 LEU D C   1 
ATOM   8494 O O   . LEU D 2 194 ? -66.203 -22.833 29.892  1   45.06  ? 364 LEU D O   1 
ATOM   8495 C CB  . LEU D 2 194 ? -64.073 -20.583 28.698  1   38.13  ? 364 LEU D CB  1 
ATOM   8496 C CG  . LEU D 2 194 ? -65.351 -19.869 28.235  1   44.98  ? 364 LEU D CG  1 
ATOM   8497 C CD1 . LEU D 2 194 ? -65.773 -18.717 29.146  1   42.1   ? 364 LEU D CD1 1 
ATOM   8498 C CD2 . LEU D 2 194 ? -65.189 -19.391 26.788  1   48.68  ? 364 LEU D CD2 1 
ATOM   8499 N N   . TYR D 2 195 ? -64.345 -23.822 29.046  1   39.21  ? 365 TYR D N   1 
ATOM   8500 C CA  . TYR D 2 195 ? -64.995 -25.054 28.635  1   37.34  ? 365 TYR D CA  1 
ATOM   8501 C C   . TYR D 2 195 ? -65.294 -25.925 29.849  1   36.39  ? 365 TYR D C   1 
ATOM   8502 O O   . TYR D 2 195 ? -66.263 -26.676 29.843  1   40.76  ? 365 TYR D O   1 
ATOM   8503 C CB  . TYR D 2 195 ? -64.109 -25.798 27.631  1   40.91  ? 365 TYR D CB  1 
ATOM   8504 C CG  . TYR D 2 195 ? -64.693 -27.074 27.026  1   46.18  ? 365 TYR D CG  1 
ATOM   8505 C CD1 . TYR D 2 195 ? -65.639 -27.033 25.999  1   47.32  ? 365 TYR D CD1 1 
ATOM   8506 C CD2 . TYR D 2 195 ? -64.27  -28.331 27.456  1   46.8   ? 365 TYR D CD2 1 
ATOM   8507 C CE1 . TYR D 2 195 ? -66.156 -28.199 25.443  1   49.3   ? 365 TYR D CE1 1 
ATOM   8508 C CE2 . TYR D 2 195 ? -64.764 -29.501 26.889  1   49.82  ? 365 TYR D CE2 1 
ATOM   8509 C CZ  . TYR D 2 195 ? -65.722 -29.442 25.885  1   50.04  ? 365 TYR D CZ  1 
ATOM   8510 O OH  . TYR D 2 195 ? -66.245 -30.588 25.332  1   48.64  ? 365 TYR D OH  1 
ATOM   8511 N N   . THR D 2 196 ? -64.447 -25.819 30.875  1   34.71  ? 366 THR D N   1 
ATOM   8512 C CA  . THR D 2 196 ? -64.478 -26.685 32.045  1   34.71  ? 366 THR D CA  1 
ATOM   8513 C C   . THR D 2 196 ? -65.59  -26.249 32.999  1   35.77  ? 366 THR D C   1 
ATOM   8514 O O   . THR D 2 196 ? -66.179 -27.078 33.7    1   33.2   ? 366 THR D O   1 
ATOM   8515 C CB  . THR D 2 196 ? -63.112 -26.668 32.738  1   35.73  ? 366 THR D CB  1 
ATOM   8516 O OG1 . THR D 2 196 ? -62.122 -27.177 31.842  1   34.47  ? 366 THR D OG1 1 
ATOM   8517 C CG2 . THR D 2 196 ? -63.103 -27.429 34.058  1   33.05  ? 366 THR D CG2 1 
ATOM   8518 N N   . VAL D 2 197 ? -65.86  -24.939 33.028  1   35.18  ? 367 VAL D N   1 
ATOM   8519 C CA  . VAL D 2 197 ? -66.777 -24.382 34.006  1   36.73  ? 367 VAL D CA  1 
ATOM   8520 C C   . VAL D 2 197 ? -68.159 -24.178 33.388  1   39.71  ? 367 VAL D C   1 
ATOM   8521 O O   . VAL D 2 197 ? -69.162 -24.382 34.071  1   40.14  ? 367 VAL D O   1 
ATOM   8522 C CB  . VAL D 2 197 ? -66.184 -23.087 34.583  1   36.69  ? 367 VAL D CB  1 
ATOM   8523 C CG1 . VAL D 2 197 ? -67.113 -22.411 35.585  1   36.87  ? 367 VAL D CG1 1 
ATOM   8524 C CG2 . VAL D 2 197 ? -64.839 -23.371 35.229  1   38.37  ? 367 VAL D CG2 1 
ATOM   8525 N N   . THR D 2 198 ? -68.206 -23.825 32.091  1   40.68  ? 368 THR D N   1 
ATOM   8526 C CA  . THR D 2 198 ? -69.441 -23.377 31.45   1   40.72  ? 368 THR D CA  1 
ATOM   8527 C C   . THR D 2 198 ? -69.861 -24.275 30.283  1   40.34  ? 368 THR D C   1 
ATOM   8528 O O   . THR D 2 198 ? -71.034 -24.27  29.922  1   40.6   ? 368 THR D O   1 
ATOM   8529 C CB  . THR D 2 198 ? -69.337 -21.911 31.018  1   41.23  ? 368 THR D CB  1 
ATOM   8530 O OG1 . THR D 2 198 ? -68.627 -21.785 29.782  1   41.35  ? 368 THR D OG1 1 
ATOM   8531 C CG2 . THR D 2 198 ? -68.731 -21.05  32.112  1   38.21  ? 368 THR D CG2 1 
ATOM   8532 N N   . GLY D 2 199 ? -68.913 -25.018 29.685  1   39.76  ? 369 GLY D N   1 
ATOM   8533 C CA  . GLY D 2 199 ? -69.178 -25.847 28.518  1   35.78  ? 369 GLY D CA  1 
ATOM   8534 C C   . GLY D 2 199 ? -68.912 -25.106 27.206  1   36.7   ? 369 GLY D C   1 
ATOM   8535 O O   . GLY D 2 199 ? -68.879 -25.716 26.141  1   37.66  ? 369 GLY D O   1 
ATOM   8536 N N   . GLN D 2 200 ? -68.698 -23.791 27.282  1   37.51  ? 370 GLN D N   1 
ATOM   8537 C CA  . GLN D 2 200 ? -68.6   -22.979 26.083  1   39.87  ? 370 GLN D CA  1 
ATOM   8538 C C   . GLN D 2 200 ? -67.169 -22.974 25.563  1   38.39  ? 370 GLN D C   1 
ATOM   8539 O O   . GLN D 2 200 ? -66.251 -23.413 26.249  1   38.19  ? 370 GLN D O   1 
ATOM   8540 C CB  . GLN D 2 200 ? -68.985 -21.545 26.413  1   46.89  ? 370 GLN D CB  1 
ATOM   8541 C CG  . GLN D 2 200 ? -70.403 -21.409 26.943  1   56.54  ? 370 GLN D CG  1 
ATOM   8542 C CD  . GLN D 2 200 ? -70.595 -20.039 27.541  1   65.76  ? 370 GLN D CD  1 
ATOM   8543 O OE1 . GLN D 2 200 ? -70.306 -19.022 26.901  1   64.4   ? 370 GLN D OE1 1 
ATOM   8544 N NE2 . GLN D 2 200 ? -71.022 -20.004 28.795  1   74.13  ? 370 GLN D NE2 1 
ATOM   8545 N N   . SER D 2 201 ? -67.005 -22.442 24.348  1   36.63  ? 371 SER D N   1 
ATOM   8546 C CA  . SER D 2 201 ? -65.731 -22.465 23.653  1   38.62  ? 371 SER D CA  1 
ATOM   8547 C C   . SER D 2 201 ? -65.174 -21.052 23.469  1   38.9   ? 371 SER D C   1 
ATOM   8548 O O   . SER D 2 201 ? -65.856 -20.056 23.701  1   42.1   ? 371 SER D O   1 
ATOM   8549 C CB  . SER D 2 201 ? -65.853 -23.185 22.332  1   38.38  ? 371 SER D CB  1 
ATOM   8550 O OG  . SER D 2 201 ? -65.999 -24.586 22.523  1   38.19  ? 371 SER D OG  1 
ATOM   8551 N N   . TRP D 2 202 ? -63.906 -21.009 23.062  1   35.84  ? 372 TRP D N   1 
ATOM   8552 C CA  . TRP D 2 202 ? -63.227 -19.838 22.537  1   37.6   ? 372 TRP D CA  1 
ATOM   8553 C C   . TRP D 2 202 ? -64.23  -19.021 21.719  1   38.94  ? 372 TRP D C   1 
ATOM   8554 O O   . TRP D 2 202 ? -64.725 -19.483 20.682  1   38.08  ? 372 TRP D O   1 
ATOM   8555 C CB  . TRP D 2 202 ? -62.008 -20.339 21.734  1   35.84  ? 372 TRP D CB  1 
ATOM   8556 C CG  . TRP D 2 202 ? -61.071 -19.324 21.133  1   34.17  ? 372 TRP D CG  1 
ATOM   8557 C CD1 . TRP D 2 202 ? -60.828 -19.15  19.801  1   34.2   ? 372 TRP D CD1 1 
ATOM   8558 C CD2 . TRP D 2 202 ? -60.211 -18.383 21.823  1   36.41  ? 372 TRP D CD2 1 
ATOM   8559 N NE1 . TRP D 2 202 ? -59.891 -18.167 19.606  1   35.92  ? 372 TRP D NE1 1 
ATOM   8560 C CE2 . TRP D 2 202 ? -59.494 -17.673 20.825  1   35.32  ? 372 TRP D CE2 1 
ATOM   8561 C CE3 . TRP D 2 202 ? -59.982 -18.061 23.172  1   37.06  ? 372 TRP D CE3 1 
ATOM   8562 C CZ2 . TRP D 2 202 ? -58.576 -16.671 21.137  1   30.28  ? 372 TRP D CZ2 1 
ATOM   8563 C CZ3 . TRP D 2 202 ? -59.08  -17.064 23.481  1   34.28  ? 372 TRP D CZ3 1 
ATOM   8564 C CH2 . TRP D 2 202 ? -58.394 -16.381 22.471  1   33.01  ? 372 TRP D CH2 1 
ATOM   8565 N N   . PRO D 2 203 ? -64.629 -17.818 22.206  1   39.35  ? 373 PRO D N   1 
ATOM   8566 C CA  . PRO D 2 203 ? -65.655 -17.022 21.526  1   37.83  ? 373 PRO D CA  1 
ATOM   8567 C C   . PRO D 2 203 ? -65.175 -16.414 20.211  1   37.98  ? 373 PRO D C   1 
ATOM   8568 O O   . PRO D 2 203 ? -63.977 -16.195 20.015  1   38.11  ? 373 PRO D O   1 
ATOM   8569 C CB  . PRO D 2 203 ? -66.051 -15.957 22.56   1   36.91  ? 373 PRO D CB  1 
ATOM   8570 C CG  . PRO D 2 203 ? -64.823 -15.828 23.438  1   36.47  ? 373 PRO D CG  1 
ATOM   8571 C CD  . PRO D 2 203 ? -64.144 -17.189 23.448  1   36.86  ? 373 PRO D CD  1 
ATOM   8572 N N   . GLU D 2 204 ? -66.143 -16.127 19.332  1   37.3   ? 374 GLU D N   1 
ATOM   8573 C CA  . GLU D 2 204 ? -65.918 -15.588 17.999  1   37.49  ? 374 GLU D CA  1 
ATOM   8574 C C   . GLU D 2 204 ? -65.255 -14.207 18.057  1   37.38  ? 374 GLU D C   1 
ATOM   8575 O O   . GLU D 2 204 ? -64.513 -13.831 17.143  1   37.92  ? 374 GLU D O   1 
ATOM   8576 C CB  . GLU D 2 204 ? -67.258 -15.586 17.257  1   38.73  ? 374 GLU D CB  1 
ATOM   8577 C CG  . GLU D 2 204 ? -67.233 -14.887 15.9    1   39.8   ? 374 GLU D CG  1 
ATOM   8578 C CD  . GLU D 2 204 ? -66.343 -15.535 14.855  1   44.42  ? 374 GLU D CD  1 
ATOM   8579 O OE1 . GLU D 2 204 ? -65.996 -16.73  15      1   44.23  ? 374 GLU D OE1 1 
ATOM   8580 O OE2 . GLU D 2 204 ? -65.975 -14.826 13.897  1   47.75  ? 374 GLU D OE2 1 
ATOM   8581 N N   . SER D 2 205 ? -65.556 -13.441 19.116  1   34.76  ? 375 SER D N   1 
ATOM   8582 C CA  . SER D 2 205 ? -65.029 -12.097 19.288  1   31.84  ? 375 SER D CA  1 
ATOM   8583 C C   . SER D 2 205 ? -63.513 -12.141 19.497  1   30.24  ? 375 SER D C   1 
ATOM   8584 O O   . SER D 2 205 ? -62.772 -11.299 18.981  1   26.88  ? 375 SER D O   1 
ATOM   8585 C CB  . SER D 2 205 ? -65.754 -11.362 20.403  1   30.33  ? 375 SER D CB  1 
ATOM   8586 O OG  . SER D 2 205 ? -65.714 -12.085 21.625  1   28.18  ? 375 SER D OG  1 
ATOM   8587 N N   . LEU D 2 206 ? -63.067 -13.151 20.246  1   29.61  ? 376 LEU D N   1 
ATOM   8588 C CA  . LEU D 2 206 ? -61.651 -13.349 20.492  1   31.56  ? 376 LEU D CA  1 
ATOM   8589 C C   . LEU D 2 206 ? -60.974 -13.93  19.248  1   33.31  ? 376 LEU D C   1 
ATOM   8590 O O   . LEU D 2 206 ? -59.795 -13.659 19.009  1   32.51  ? 376 LEU D O   1 
ATOM   8591 C CB  . LEU D 2 206 ? -61.43  -14.214 21.729  1   28.55  ? 376 LEU D CB  1 
ATOM   8592 C CG  . LEU D 2 206 ? -61.532 -13.48  23.067  1   28.23  ? 376 LEU D CG  1 
ATOM   8593 C CD1 . LEU D 2 206 ? -61.308 -14.428 24.237  1   27.18  ? 376 LEU D CD1 1 
ATOM   8594 C CD2 . LEU D 2 206 ? -60.533 -12.334 23.128  1   28.92  ? 376 LEU D CD2 1 
ATOM   8595 N N   . VAL D 2 207 ? -61.726 -14.707 18.456  1   29.13  ? 377 VAL D N   1 
ATOM   8596 C CA  . VAL D 2 207 ? -61.24  -15.141 17.156  1   30.45  ? 377 VAL D CA  1 
ATOM   8597 C C   . VAL D 2 207 ? -60.947 -13.908 16.301  1   33.23  ? 377 VAL D C   1 
ATOM   8598 O O   . VAL D 2 207 ? -59.886 -13.824 15.684  1   36.87  ? 377 VAL D O   1 
ATOM   8599 C CB  . VAL D 2 207 ? -62.2   -16.104 16.428  1   30.88  ? 377 VAL D CB  1 
ATOM   8600 C CG1 . VAL D 2 207 ? -61.712 -16.464 15.029  1   27.95  ? 377 VAL D CG1 1 
ATOM   8601 C CG2 . VAL D 2 207 ? -62.47  -17.366 17.234  1   29.89  ? 377 VAL D CG2 1 
ATOM   8602 N N   . GLN D 2 208 ? -61.89  -12.956 16.264  1   34.2   ? 378 GLN D N   1 
ATOM   8603 C CA  . GLN D 2 208 ? -61.669 -11.714 15.54   1   37.36  ? 378 GLN D CA  1 
ATOM   8604 C C   . GLN D 2 208 ? -60.464 -10.959 16.115  1   37.5   ? 378 GLN D C   1 
ATOM   8605 O O   . GLN D 2 208 ? -59.619 -10.473 15.364  1   38.52  ? 378 GLN D O   1 
ATOM   8606 C CB  . GLN D 2 208 ? -62.922 -10.836 15.517  1   42.83  ? 378 GLN D CB  1 
ATOM   8607 C CG  . GLN D 2 208 ? -63.998 -11.287 14.535  1   51.84  ? 378 GLN D CG  1 
ATOM   8608 C CD  . GLN D 2 208 ? -63.494 -11.402 13.11   1   58.84  ? 378 GLN D CD  1 
ATOM   8609 O OE1 . GLN D 2 208 ? -63.322 -12.508 12.583  1   53.6   ? 378 GLN D OE1 1 
ATOM   8610 N NE2 . GLN D 2 208 ? -63.218 -10.264 12.483  1   60.51  ? 378 GLN D NE2 1 
ATOM   8611 N N   . LYS D 2 209 ? -60.372 -10.865 17.448  1   32.88  ? 379 LYS D N   1 
ATOM   8612 C CA  . LYS D 2 209 ? -59.355 -10.042 18.075  1   31.66  ? 379 LYS D CA  1 
ATOM   8613 C C   . LYS D 2 209 ? -57.953 -10.575 17.771  1   32.93  ? 379 LYS D C   1 
ATOM   8614 O O   . LYS D 2 209 ? -57.066 -9.771  17.48   1   31.34  ? 379 LYS D O   1 
ATOM   8615 C CB  . LYS D 2 209 ? -59.578 -9.924  19.588  1   33.98  ? 379 LYS D CB  1 
ATOM   8616 C CG  . LYS D 2 209 ? -58.671 -8.914  20.295  1   35.61  ? 379 LYS D CG  1 
ATOM   8617 C CD  . LYS D 2 209 ? -58.671 -9.04   21.813  1   35.87  ? 379 LYS D CD  1 
ATOM   8618 C CE  . LYS D 2 209 ? -57.777 -8.073  22.518  1   30.64  ? 379 LYS D CE  1 
ATOM   8619 N NZ  . LYS D 2 209 ? -58.187 -6.713  22.173  1   32.62  ? 379 LYS D NZ  1 
ATOM   8620 N N   . THR D 2 210 ? -57.775 -11.914 17.842  1   34.55  ? 380 THR D N   1 
ATOM   8621 C CA  . THR D 2 210 ? -56.474 -12.594 17.903  1   32.92  ? 380 THR D CA  1 
ATOM   8622 C C   . THR D 2 210 ? -56.081 -13.232 16.568  1   34.52  ? 380 THR D C   1 
ATOM   8623 O O   . THR D 2 210 ? -54.896 -13.519 16.325  1   32.4   ? 380 THR D O   1 
ATOM   8624 C CB  . THR D 2 210 ? -56.485 -13.679 18.98   1   32.38  ? 380 THR D CB  1 
ATOM   8625 O OG1 . THR D 2 210 ? -57.42  -14.689 18.586  1   32.72  ? 380 THR D OG1 1 
ATOM   8626 C CG2 . THR D 2 210 ? -56.805 -13.106 20.348  1   30.59  ? 380 THR D CG2 1 
ATOM   8627 N N   . GLY D 2 211 ? -57.092 -13.512 15.733  1   31.4   ? 381 GLY D N   1 
ATOM   8628 C CA  . GLY D 2 211 ? -56.859 -14.278 14.524  1   29.08  ? 381 GLY D CA  1 
ATOM   8629 C C   . GLY D 2 211 ? -56.566 -15.748 14.819  1   29.23  ? 381 GLY D C   1 
ATOM   8630 O O   . GLY D 2 211 ? -56.191 -16.477 13.911  1   32.35  ? 381 GLY D O   1 
ATOM   8631 N N   . TYR D 2 212 ? -56.735 -16.18  16.073  1   29.24  ? 382 TYR D N   1 
ATOM   8632 C CA  . TYR D 2 212 ? -56.534 -17.569 16.46   1   30.12  ? 382 TYR D CA  1 
ATOM   8633 C C   . TYR D 2 212 ? -57.877 -18.296 16.412  1   31.83  ? 382 TYR D C   1 
ATOM   8634 O O   . TYR D 2 212 ? -58.889 -17.721 16.807  1   33.28  ? 382 TYR D O   1 
ATOM   8635 C CB  . TYR D 2 212 ? -55.981 -17.697 17.885  1   28.56  ? 382 TYR D CB  1 
ATOM   8636 C CG  . TYR D 2 212 ? -54.627 -17.061 18.165  1   28.79  ? 382 TYR D CG  1 
ATOM   8637 C CD1 . TYR D 2 212 ? -53.679 -16.868 17.156  1   27.84  ? 382 TYR D CD1 1 
ATOM   8638 C CD2 . TYR D 2 212 ? -54.303 -16.644 19.452  1   27.1   ? 382 TYR D CD2 1 
ATOM   8639 C CE1 . TYR D 2 212 ? -52.459 -16.263 17.429  1   26.75  ? 382 TYR D CE1 1 
ATOM   8640 C CE2 . TYR D 2 212 ? -53.085 -16.048 19.74   1   26.33  ? 382 TYR D CE2 1 
ATOM   8641 C CZ  . TYR D 2 212 ? -52.163 -15.859 18.725  1   26.53  ? 382 TYR D CZ  1 
ATOM   8642 O OH  . TYR D 2 212 ? -50.971 -15.289 19.04   1   23.61  ? 382 TYR D OH  1 
ATOM   8643 N N   . THR D 2 213 ? -57.867 -19.555 15.942  1   31.06  ? 383 THR D N   1 
ATOM   8644 C CA  . THR D 2 213 ? -59.033 -20.43  15.954  1   33.37  ? 383 THR D CA  1 
ATOM   8645 C C   . THR D 2 213 ? -58.682 -21.694 16.725  1   34.27  ? 383 THR D C   1 
ATOM   8646 O O   . THR D 2 213 ? -57.507 -22.018 16.859  1   36.13  ? 383 THR D O   1 
ATOM   8647 C CB  . THR D 2 213 ? -59.488 -20.767 14.534  1   32.91  ? 383 THR D CB  1 
ATOM   8648 O OG1 . THR D 2 213 ? -58.35  -21.256 13.83   1   37.29  ? 383 THR D OG1 1 
ATOM   8649 C CG2 . THR D 2 213 ? -60.023 -19.561 13.787  1   30.72  ? 383 THR D CG2 1 
ATOM   8650 N N   . LEU D 2 214 ? -59.705 -22.418 17.191  1   35.61  ? 384 LEU D N   1 
ATOM   8651 C CA  . LEU D 2 214 ? -59.496 -23.683 17.883  1   36.98  ? 384 LEU D CA  1 
ATOM   8652 C C   . LEU D 2 214 ? -58.593 -24.611 17.068  1   37.28  ? 384 LEU D C   1 
ATOM   8653 O O   . LEU D 2 214 ? -57.913 -25.467 17.628  1   35.29  ? 384 LEU D O   1 
ATOM   8654 C CB  . LEU D 2 214 ? -60.836 -24.349 18.195  1   35.97  ? 384 LEU D CB  1 
ATOM   8655 C CG  . LEU D 2 214 ? -61.706 -23.671 19.256  1   33.31  ? 384 LEU D CG  1 
ATOM   8656 C CD1 . LEU D 2 214 ? -63.017 -24.388 19.41   1   33.75  ? 384 LEU D CD1 1 
ATOM   8657 C CD2 . LEU D 2 214 ? -60.999 -23.674 20.574  1   34.52  ? 384 LEU D CD2 1 
ATOM   8658 N N   . GLU D 2 215 ? -58.594 -24.437 15.742  1   40.42  ? 385 GLU D N   1 
ATOM   8659 C CA  . GLU D 2 215 ? -57.718 -25.2   14.871  1   44.47  ? 385 GLU D CA  1 
ATOM   8660 C C   . GLU D 2 215 ? -56.265 -24.84  15.197  1   45.96  ? 385 GLU D C   1 
ATOM   8661 O O   . GLU D 2 215 ? -55.468 -25.701 15.562  1   45.7   ? 385 GLU D O   1 
ATOM   8662 C CB  . GLU D 2 215 ? -58.142 -24.977 13.417  1   49.2   ? 385 GLU D CB  1 
ATOM   8663 C CG  . GLU D 2 215 ? -57.768 -26.126 12.484  1   61.97  ? 385 GLU D CG  1 
ATOM   8664 C CD  . GLU D 2 215 ? -57.989 -25.886 10.997  1   74.62  ? 385 GLU D CD  1 
ATOM   8665 O OE1 . GLU D 2 215 ? -59.155 -25.893 10.547  1   78.89  ? 385 GLU D OE1 1 
ATOM   8666 O OE2 . GLU D 2 215 ? -56.988 -25.685 10.276  1   79.2   ? 385 GLU D OE2 1 
ATOM   8667 N N   . THR D 2 216 ? -55.928 -23.548 15.102  1   43.45  ? 386 THR D N   1 
ATOM   8668 C CA  . THR D 2 216 ? -54.569 -23.086 15.335  1   45.5   ? 386 THR D CA  1 
ATOM   8669 C C   . THR D 2 216 ? -54.159 -23.273 16.805  1   44.59  ? 386 THR D C   1 
ATOM   8670 O O   . THR D 2 216 ? -52.975 -23.42  17.101  1   44.66  ? 386 THR D O   1 
ATOM   8671 C CB  . THR D 2 216 ? -54.416 -21.643 14.844  1   48.07  ? 386 THR D CB  1 
ATOM   8672 O OG1 . THR D 2 216 ? -55.296 -20.853 15.64   1   48.13  ? 386 THR D OG1 1 
ATOM   8673 C CG2 . THR D 2 216 ? -54.686 -21.484 13.352  1   41.19  ? 386 THR D CG2 1 
ATOM   8674 N N   . LEU D 2 217 ? -55.135 -23.291 17.728  1   39.84  ? 387 LEU D N   1 
ATOM   8675 C CA  . LEU D 2 217 ? -54.874 -23.443 19.156  1   31.51  ? 387 LEU D CA  1 
ATOM   8676 C C   . LEU D 2 217 ? -54.754 -24.91  19.559  1   30.92  ? 387 LEU D C   1 
ATOM   8677 O O   . LEU D 2 217 ? -54.432 -25.184 20.703  1   32.28  ? 387 LEU D O   1 
ATOM   8678 C CB  . LEU D 2 217 ? -55.98  -22.795 19.984  1   27.82  ? 387 LEU D CB  1 
ATOM   8679 C CG  . LEU D 2 217 ? -56.068 -21.272 19.939  1   26.97  ? 387 LEU D CG  1 
ATOM   8680 C CD1 . LEU D 2 217 ? -57.273 -20.79  20.743  1   26.17  ? 387 LEU D CD1 1 
ATOM   8681 C CD2 . LEU D 2 217 ? -54.784 -20.645 20.439  1   26.13  ? 387 LEU D CD2 1 
ATOM   8682 N N   . LYS D 2 218 ? -55.078 -25.838 18.655  1   30.93  ? 388 LYS D N   1 
ATOM   8683 C CA  . LYS D 2 218 ? -55.171 -27.255 18.986  1   34.31  ? 388 LYS D CA  1 
ATOM   8684 C C   . LYS D 2 218 ? -53.883 -27.769 19.633  1   34.68  ? 388 LYS D C   1 
ATOM   8685 O O   . LYS D 2 218 ? -53.92  -28.242 20.768  1   35.9   ? 388 LYS D O   1 
ATOM   8686 C CB  . LYS D 2 218 ? -55.513 -28.111 17.756  1   38.18  ? 388 LYS D CB  1 
ATOM   8687 C CG  . LYS D 2 218 ? -55.3   -29.61  17.939  1   40.75  ? 388 LYS D CG  1 
ATOM   8688 C CD  . LYS D 2 218 ? -56.513 -30.375 18.455  1   42.01  ? 388 LYS D CD  1 
ATOM   8689 C CE  . LYS D 2 218 ? -57.416 -30.746 17.334  1   41.76  ? 388 LYS D CE  1 
ATOM   8690 N NZ  . LYS D 2 218 ? -56.635 -31.461 16.328  1   42.46  ? 388 LYS D NZ  1 
ATOM   8691 N N   . PRO D 2 219 ? -52.718 -27.734 18.935  1   35.04  ? 389 PRO D N   1 
ATOM   8692 C CA  . PRO D 2 219 ? -51.47  -28.263 19.497  1   36.12  ? 389 PRO D CA  1 
ATOM   8693 C C   . PRO D 2 219 ? -51.323 -27.866 20.963  1   35.11  ? 389 PRO D C   1 
ATOM   8694 O O   . PRO D 2 219 ? -51.28  -28.725 21.843  1   34.97  ? 389 PRO D O   1 
ATOM   8695 C CB  . PRO D 2 219 ? -50.383 -27.64  18.605  1   34.5   ? 389 PRO D CB  1 
ATOM   8696 C CG  . PRO D 2 219 ? -51.075 -27.537 17.264  1   33.48  ? 389 PRO D CG  1 
ATOM   8697 C CD  . PRO D 2 219 ? -52.522 -27.153 17.594  1   33.31  ? 389 PRO D CD  1 
ATOM   8698 N N   . CYS D 2 220 ? -51.34  -26.55  21.21   1   35.73  ? 390 CYS D N   1 
ATOM   8699 C CA  . CYS D 2 220 ? -51.203 -25.998 22.552  1   35.99  ? 390 CYS D CA  1 
ATOM   8700 C C   . CYS D 2 220 ? -52.266 -26.586 23.484  1   34.29  ? 390 CYS D C   1 
ATOM   8701 O O   . CYS D 2 220 ? -51.968 -26.955 24.617  1   34.03  ? 390 CYS D O   1 
ATOM   8702 C CB  . CYS D 2 220 ? -51.27  -24.475 22.517  1   35.29  ? 390 CYS D CB  1 
ATOM   8703 S SG  . CYS D 2 220 ? -50.78  -23.686 24.072  1   36.76  ? 390 CYS D SG  1 
ATOM   8704 N N   . LEU D 2 221 ? -53.501 -26.694 22.988  1   34.73  ? 391 LEU D N   1 
ATOM   8705 C CA  . LEU D 2 221 ? -54.627 -27.161 23.782  1   37.13  ? 391 LEU D CA  1 
ATOM   8706 C C   . LEU D 2 221 ? -54.416 -28.626 24.189  1   35.43  ? 391 LEU D C   1 
ATOM   8707 O O   . LEU D 2 221 ? -54.782 -29.037 25.291  1   30.38  ? 391 LEU D O   1 
ATOM   8708 C CB  . LEU D 2 221 ? -55.912 -26.965 22.975  1   42.04  ? 391 LEU D CB  1 
ATOM   8709 C CG  . LEU D 2 221 ? -56.575 -25.581 23.05   1   46.01  ? 391 LEU D CG  1 
ATOM   8710 C CD1 . LEU D 2 221 ? -55.755 -24.459 22.433  1   47.8   ? 391 LEU D CD1 1 
ATOM   8711 C CD2 . LEU D 2 221 ? -57.977 -25.585 22.466  1   46.97  ? 391 LEU D CD2 1 
ATOM   8712 N N   . LEU D 2 222 ? -53.774 -29.406 23.31   1   38.13  ? 392 LEU D N   1 
ATOM   8713 C CA  . LEU D 2 222 ? -53.545 -30.823 23.558  1   37.6   ? 392 LEU D CA  1 
ATOM   8714 C C   . LEU D 2 222 ? -52.521 -31.002 24.676  1   38.89  ? 392 LEU D C   1 
ATOM   8715 O O   . LEU D 2 222 ? -52.686 -31.874 25.522  1   43.8   ? 392 LEU D O   1 
ATOM   8716 C CB  . LEU D 2 222 ? -53.167 -31.575 22.28   1   33.73  ? 392 LEU D CB  1 
ATOM   8717 C CG  . LEU D 2 222 ? -54.287 -31.756 21.242  1   30.28  ? 392 LEU D CG  1 
ATOM   8718 C CD1 . LEU D 2 222 ? -53.776 -32.453 19.986  1   27.25  ? 392 LEU D CD1 1 
ATOM   8719 C CD2 . LEU D 2 222 ? -55.505 -32.481 21.831  1   27.53  ? 392 LEU D CD2 1 
ATOM   8720 N N   . ASP D 2 223 ? -51.479 -30.162 24.681  1   39.8   ? 393 ASP D N   1 
ATOM   8721 C CA  . ASP D 2 223 ? -50.437 -30.246 25.692  1   36.42  ? 393 ASP D CA  1 
ATOM   8722 C C   . ASP D 2 223 ? -50.992 -29.804 27.038  1   34.19  ? 393 ASP D C   1 
ATOM   8723 O O   . ASP D 2 223 ? -50.747 -30.466 28.04   1   41.83  ? 393 ASP D O   1 
ATOM   8724 C CB  . ASP D 2 223 ? -49.197 -29.44  25.333  1   36.54  ? 393 ASP D CB  1 
ATOM   8725 C CG  . ASP D 2 223 ? -48.294 -30.04  24.264  1   36.41  ? 393 ASP D CG  1 
ATOM   8726 O OD1 . ASP D 2 223 ? -48.035 -31.261 24.332  1   39.55  ? 393 ASP D OD1 1 
ATOM   8727 O OD2 . ASP D 2 223 ? -47.832 -29.28  23.395  1   32.22  ? 393 ASP D OD2 1 
ATOM   8728 N N   . LEU D 2 224 ? -51.697 -28.667 27.047  1   28.37  ? 394 LEU D N   1 
ATOM   8729 C CA  . LEU D 2 224 ? -52.21  -28.05  28.259  1   28.39  ? 394 LEU D CA  1 
ATOM   8730 C C   . LEU D 2 224 ? -53.292 -28.918 28.898  1   28.43  ? 394 LEU D C   1 
ATOM   8731 O O   . LEU D 2 224 ? -53.392 -29.008 30.119  1   28.12  ? 394 LEU D O   1 
ATOM   8732 C CB  . LEU D 2 224 ? -52.739 -26.663 27.904  1   27.82  ? 394 LEU D CB  1 
ATOM   8733 C CG  . LEU D 2 224 ? -52.916 -25.694 29.077  1   26     ? 394 LEU D CG  1 
ATOM   8734 C CD1 . LEU D 2 224 ? -51.588 -25.422 29.765  1   24.13  ? 394 LEU D CD1 1 
ATOM   8735 C CD2 . LEU D 2 224 ? -53.571 -24.39  28.653  1   23.99  ? 394 LEU D CD2 1 
ATOM   8736 N N   . HIS D 2 225 ? -54.102 -29.56  28.06   1   31.86  ? 395 HIS D N   1 
ATOM   8737 C CA  . HIS D 2 225 ? -55.06  -30.542 28.54   1   30.81  ? 395 HIS D CA  1 
ATOM   8738 C C   . HIS D 2 225 ? -54.333 -31.671 29.279  1   32.1   ? 395 HIS D C   1 
ATOM   8739 O O   . HIS D 2 225 ? -54.715 -32.025 30.4    1   32.21  ? 395 HIS D O   1 
ATOM   8740 C CB  . HIS D 2 225 ? -55.913 -31.035 27.369  1   30.44  ? 395 HIS D CB  1 
ATOM   8741 C CG  . HIS D 2 225 ? -57.053 -31.924 27.761  1   30.18  ? 395 HIS D CG  1 
ATOM   8742 N ND1 . HIS D 2 225 ? -57.809 -31.726 28.9    1   27.17  ? 395 HIS D ND1 1 
ATOM   8743 C CD2 . HIS D 2 225 ? -57.553 -33.006 27.155  1   27.71  ? 395 HIS D CD2 1 
ATOM   8744 C CE1 . HIS D 2 225 ? -58.741 -32.648 28.963  1   26.6   ? 395 HIS D CE1 1 
ATOM   8745 N NE2 . HIS D 2 225 ? -58.598 -33.434 27.918  1   27.96  ? 395 HIS D NE2 1 
ATOM   8746 N N   . GLN D 2 226 ? -53.282 -32.22  28.647  1   32.43  ? 396 GLN D N   1 
ATOM   8747 C CA  . GLN D 2 226 ? -52.475 -33.278 29.237  1   35.74  ? 396 GLN D CA  1 
ATOM   8748 C C   . GLN D 2 226 ? -51.883 -32.787 30.557  1   33.41  ? 396 GLN D C   1 
ATOM   8749 O O   . GLN D 2 226 ? -51.929 -33.485 31.564  1   32.15  ? 396 GLN D O   1 
ATOM   8750 C CB  . GLN D 2 226 ? -51.371 -33.759 28.291  1   40.07  ? 396 GLN D CB  1 
ATOM   8751 C CG  . GLN D 2 226 ? -50.946 -35.211 28.51   1   49.78  ? 396 GLN D CG  1 
ATOM   8752 C CD  . GLN D 2 226 ? -52.043 -36.225 28.211  1   62.6   ? 396 GLN D CD  1 
ATOM   8753 O OE1 . GLN D 2 226 ? -52.808 -36.095 27.246  1   62.05  ? 396 GLN D OE1 1 
ATOM   8754 N NE2 . GLN D 2 226 ? -52.162 -37.246 29.053  1   64.03  ? 396 GLN D NE2 1 
ATOM   8755 N N   . THR D 2 227 ? -51.352 -31.565 30.539  1   31.86  ? 397 THR D N   1 
ATOM   8756 C CA  . THR D 2 227 ? -50.736 -31.001 31.726  1   33.19  ? 397 THR D CA  1 
ATOM   8757 C C   . THR D 2 227 ? -51.788 -30.916 32.84   1   37.03  ? 397 THR D C   1 
ATOM   8758 O O   . THR D 2 227 ? -51.497 -31.26  33.986  1   39.62  ? 397 THR D O   1 
ATOM   8759 C CB  . THR D 2 227 ? -50.064 -29.663 31.403  1   29.36  ? 397 THR D CB  1 
ATOM   8760 O OG1 . THR D 2 227 ? -49.016 -29.931 30.478  1   30.67  ? 397 THR D OG1 1 
ATOM   8761 C CG2 . THR D 2 227 ? -49.457 -28.99  32.616  1   26.33  ? 397 THR D CG2 1 
ATOM   8762 N N   . TYR D 2 228 ? -53.016 -30.497 32.492  1   35.03  ? 398 TYR D N   1 
ATOM   8763 C CA  . TYR D 2 228 ? -54.074 -30.284 33.473  1   34     ? 398 TYR D CA  1 
ATOM   8764 C C   . TYR D 2 228 ? -54.413 -31.62  34.131  1   35.1   ? 398 TYR D C   1 
ATOM   8765 O O   . TYR D 2 228 ? -54.628 -31.679 35.34   1   35.04  ? 398 TYR D O   1 
ATOM   8766 C CB  . TYR D 2 228 ? -55.256 -29.551 32.82   1   32.13  ? 398 TYR D CB  1 
ATOM   8767 C CG  . TYR D 2 228 ? -56.407 -29.131 33.726  1   31.23  ? 398 TYR D CG  1 
ATOM   8768 C CD1 . TYR D 2 228 ? -56.288 -29.128 35.113  1   30.94  ? 398 TYR D CD1 1 
ATOM   8769 C CD2 . TYR D 2 228 ? -57.622 -28.719 33.183  1   32.77  ? 398 TYR D CD2 1 
ATOM   8770 C CE1 . TYR D 2 228 ? -57.35  -28.757 35.925  1   32.32  ? 398 TYR D CE1 1 
ATOM   8771 C CE2 . TYR D 2 228 ? -58.695 -28.352 33.987  1   34.24  ? 398 TYR D CE2 1 
ATOM   8772 C CZ  . TYR D 2 228 ? -58.555 -28.358 35.368  1   34.06  ? 398 TYR D CZ  1 
ATOM   8773 O OH  . TYR D 2 228 ? -59.58  -27.983 36.198  1   31.09  ? 398 TYR D OH  1 
ATOM   8774 N N   . LEU D 2 229 ? -54.408 -32.687 33.318  1   36.77  ? 399 LEU D N   1 
ATOM   8775 C CA  . LEU D 2 229 ? -54.789 -34.033 33.729  1   37.92  ? 399 LEU D CA  1 
ATOM   8776 C C   . LEU D 2 229 ? -53.745 -34.665 34.647  1   38.99  ? 399 LEU D C   1 
ATOM   8777 O O   . LEU D 2 229 ? -54.105 -35.277 35.644  1   41.01  ? 399 LEU D O   1 
ATOM   8778 C CB  . LEU D 2 229 ? -55.042 -34.903 32.501  1   34.93  ? 399 LEU D CB  1 
ATOM   8779 C CG  . LEU D 2 229 ? -56.336 -34.617 31.736  1   31.24  ? 399 LEU D CG  1 
ATOM   8780 C CD1 . LEU D 2 229 ? -56.249 -35.198 30.335  1   28.8   ? 399 LEU D CD1 1 
ATOM   8781 C CD2 . LEU D 2 229 ? -57.533 -35.165 32.487  1   26.93  ? 399 LEU D CD2 1 
ATOM   8782 N N   . ARG D 2 230 ? -52.462 -34.531 34.299  1   42.12  ? 400 ARG D N   1 
ATOM   8783 C CA  . ARG D 2 230 ? -51.373 -35.118 35.066  1   42.46  ? 400 ARG D CA  1 
ATOM   8784 C C   . ARG D 2 230 ? -51.046 -34.259 36.29   1   39.07  ? 400 ARG D C   1 
ATOM   8785 O O   . ARG D 2 230 ? -50.209 -34.652 37.1    1   37.4   ? 400 ARG D O   1 
ATOM   8786 C CB  . ARG D 2 230 ? -50.155 -35.322 34.152  1   44.45  ? 400 ARG D CB  1 
ATOM   8787 C CG  . ARG D 2 230 ? -50.371 -36.451 33.154  1   49.23  ? 400 ARG D CG  1 
ATOM   8788 C CD  . ARG D 2 230 ? -49.67  -36.327 31.804  1   54.67  ? 400 ARG D CD  1 
ATOM   8789 N NE  . ARG D 2 230 ? -49.909 -37.605 31.117  1   66.6   ? 400 ARG D NE  1 
ATOM   8790 C CZ  . ARG D 2 230 ? -49.379 -38.078 29.985  1   65.56  ? 400 ARG D CZ  1 
ATOM   8791 N NH1 . ARG D 2 230 ? -48.6   -37.323 29.223  1   66.21  ? 400 ARG D NH1 1 
ATOM   8792 N NH2 . ARG D 2 230 ? -49.646 -39.322 29.622  1   56.78  ? 400 ARG D NH2 1 
ATOM   8793 N N   . ALA D 2 231 ? -51.726 -33.112 36.435  1   35.91  ? 401 ALA D N   1 
ATOM   8794 C CA  . ALA D 2 231 ? -51.28  -32.061 37.345  1   36.48  ? 401 ALA D CA  1 
ATOM   8795 C C   . ALA D 2 231 ? -51.12  -32.55  38.789  1   35.46  ? 401 ALA D C   1 
ATOM   8796 O O   . ALA D 2 231 ? -50.145 -32.187 39.442  1   32.76  ? 401 ALA D O   1 
ATOM   8797 C CB  . ALA D 2 231 ? -52.156 -30.831 37.242  1   34.41  ? 401 ALA D CB  1 
ATOM   8798 N N   . PRO D 2 232 ? -52.051 -33.369 39.342  1   36.08  ? 402 PRO D N   1 
ATOM   8799 C CA  . PRO D 2 232 ? -51.88  -33.942 40.683  1   35.18  ? 402 PRO D CA  1 
ATOM   8800 C C   . PRO D 2 232 ? -50.672 -34.858 40.856  1   34.14  ? 402 PRO D C   1 
ATOM   8801 O O   . PRO D 2 232 ? -50.266 -35.113 41.985  1   33.22  ? 402 PRO D O   1 
ATOM   8802 C CB  . PRO D 2 232 ? -53.181 -34.712 40.938  1   32.79  ? 402 PRO D CB  1 
ATOM   8803 C CG  . PRO D 2 232 ? -54.161 -34.125 39.955  1   33.74  ? 402 PRO D CG  1 
ATOM   8804 C CD  . PRO D 2 232 ? -53.333 -33.759 38.735  1   34.87  ? 402 PRO D CD  1 
ATOM   8805 N N   . GLN D 2 233 ? -50.126 -35.35  39.735  1   34.74  ? 403 GLN D N   1 
ATOM   8806 C CA  . GLN D 2 233 ? -48.992 -36.27  39.711  1   38.07  ? 403 GLN D CA  1 
ATOM   8807 C C   . GLN D 2 233 ? -47.665 -35.547 39.452  1   35.09  ? 403 GLN D C   1 
ATOM   8808 O O   . GLN D 2 233 ? -46.603 -36.132 39.653  1   33.55  ? 403 GLN D O   1 
ATOM   8809 C CB  . GLN D 2 233 ? -49.159 -37.364 38.65   1   39.93  ? 403 GLN D CB  1 
ATOM   8810 C CG  . GLN D 2 233 ? -49.486 -38.753 39.187  1   39.52  ? 403 GLN D CG  1 
ATOM   8811 C CD  . GLN D 2 233 ? -50.797 -38.813 39.932  1   40.79  ? 403 GLN D CD  1 
ATOM   8812 O OE1 . GLN D 2 233 ? -50.84  -39.234 41.093  1   43.33  ? 403 GLN D OE1 1 
ATOM   8813 N NE2 . GLN D 2 233 ? -51.876 -38.408 39.271  1   38.09  ? 403 GLN D NE2 1 
ATOM   8814 N N   . HIS D 2 234 ? -47.717 -34.293 38.986  1   31.54  ? 404 HIS D N   1 
ATOM   8815 C CA  . HIS D 2 234 ? -46.503 -33.561 38.674  1   29.6   ? 404 HIS D CA  1 
ATOM   8816 C C   . HIS D 2 234 ? -45.581 -33.551 39.896  1   28.49  ? 404 HIS D C   1 
ATOM   8817 O O   . HIS D 2 234 ? -46.048 -33.508 41.028  1   28.3   ? 404 HIS D O   1 
ATOM   8818 C CB  . HIS D 2 234 ? -46.85  -32.148 38.202  1   32.83  ? 404 HIS D CB  1 
ATOM   8819 C CG  . HIS D 2 234 ? -45.777 -31.533 37.357  1   38.49  ? 404 HIS D CG  1 
ATOM   8820 N ND1 . HIS D 2 234 ? -44.535 -31.154 37.837  1   38.54  ? 404 HIS D ND1 1 
ATOM   8821 C CD2 . HIS D 2 234 ? -45.768 -31.267 36.047  1   36.78  ? 404 HIS D CD2 1 
ATOM   8822 C CE1 . HIS D 2 234 ? -43.806 -30.673 36.847  1   39.25  ? 404 HIS D CE1 1 
ATOM   8823 N NE2 . HIS D 2 234 ? -44.541 -30.73  35.752  1   42.11  ? 404 HIS D NE2 1 
ATOM   8824 N N   . ALA D 2 235 ? -44.263 -33.591 39.669  1   28.76  ? 405 ALA D N   1 
ATOM   8825 C CA  . ALA D 2 235 ? -43.299 -33.529 40.759  1   27.97  ? 405 ALA D CA  1 
ATOM   8826 C C   . ALA D 2 235 ? -43.435 -32.206 41.512  1   28.67  ? 405 ALA D C   1 
ATOM   8827 O O   . ALA D 2 235 ? -43.16  -32.159 42.7    1   31.57  ? 405 ALA D O   1 
ATOM   8828 C CB  . ALA D 2 235 ? -41.883 -33.733 40.244  1   25.41  ? 405 ALA D CB  1 
ATOM   8829 N N   . GLN D 2 236 ? -43.871 -31.147 40.818  1   28.87  ? 406 GLN D N   1 
ATOM   8830 C CA  . GLN D 2 236 ? -44     -29.796 41.357  1   31     ? 406 GLN D CA  1 
ATOM   8831 C C   . GLN D 2 236 ? -45.477 -29.423 41.541  1   32.43  ? 406 GLN D C   1 
ATOM   8832 O O   . GLN D 2 236 ? -46.274 -29.5   40.596  1   32.35  ? 406 GLN D O   1 
ATOM   8833 C CB  . GLN D 2 236 ? -43.257 -28.795 40.466  1   29.99  ? 406 GLN D CB  1 
ATOM   8834 C CG  . GLN D 2 236 ? -41.763 -28.67  40.738  1   30.86  ? 406 GLN D CG  1 
ATOM   8835 C CD  . GLN D 2 236 ? -40.932 -29.849 40.28   1   34.97  ? 406 GLN D CD  1 
ATOM   8836 O OE1 . GLN D 2 236 ? -41.161 -30.411 39.203  1   40.81  ? 406 GLN D OE1 1 
ATOM   8837 N NE2 . GLN D 2 236 ? -39.946 -30.224 41.087  1   34.67  ? 406 GLN D NE2 1 
ATOM   8838 N N   . GLN D 2 237 ? -45.8   -28.974 42.767  1   31.5   ? 407 GLN D N   1 
ATOM   8839 C CA  . GLN D 2 237 ? -47.15  -28.957 43.312  1   32.95  ? 407 GLN D CA  1 
ATOM   8840 C C   . GLN D 2 237 ? -47.537 -27.573 43.832  1   33.49  ? 407 GLN D C   1 
ATOM   8841 O O   . GLN D 2 237 ? -48.709 -27.354 44.152  1   37.86  ? 407 GLN D O   1 
ATOM   8842 C CB  . GLN D 2 237 ? -47.282 -29.969 44.456  1   29.68  ? 407 GLN D CB  1 
ATOM   8843 C CG  . GLN D 2 237 ? -47.335 -31.416 43.984  1   28.76  ? 407 GLN D CG  1 
ATOM   8844 C CD  . GLN D 2 237 ? -48.505 -31.674 43.058  1   33.12  ? 407 GLN D CD  1 
ATOM   8845 O OE1 . GLN D 2 237 ? -49.638 -31.243 43.305  1   34.33  ? 407 GLN D OE1 1 
ATOM   8846 N NE2 . GLN D 2 237 ? -48.251 -32.383 41.969  1   36.27  ? 407 GLN D NE2 1 
ATOM   8847 N N   . SER D 2 238 ? -46.568 -26.651 43.909  1   29.45  ? 408 SER D N   1 
ATOM   8848 C CA  . SER D 2 238 ? -46.794 -25.363 44.546  1   30.03  ? 408 SER D CA  1 
ATOM   8849 C C   . SER D 2 238 ? -47.983 -24.615 43.926  1   29.72  ? 408 SER D C   1 
ATOM   8850 O O   . SER D 2 238 ? -48.733 -23.943 44.63   1   29.99  ? 408 SER D O   1 
ATOM   8851 C CB  . SER D 2 238 ? -45.531 -24.526 44.543  1   29.48  ? 408 SER D CB  1 
ATOM   8852 O OG  . SER D 2 238 ? -44.483 -25.139 45.28   1   26.26  ? 408 SER D OG  1 
ATOM   8853 N N   . ILE D 2 239 ? -48.163 -24.734 42.606  1   30.84  ? 409 ILE D N   1 
ATOM   8854 C CA  . ILE D 2 239 ? -49.203 -23.996 41.904  1   30.2   ? 409 ILE D CA  1 
ATOM   8855 C C   . ILE D 2 239 ? -50.572 -24.599 42.236  1   33.89  ? 409 ILE D C   1 
ATOM   8856 O O   . ILE D 2 239 ? -51.537 -23.858 42.379  1   33.61  ? 409 ILE D O   1 
ATOM   8857 C CB  . ILE D 2 239 ? -48.912 -23.9   40.394  1   27.74  ? 409 ILE D CB  1 
ATOM   8858 C CG1 . ILE D 2 239 ? -47.577 -23.198 40.104  1   27.16  ? 409 ILE D CG1 1 
ATOM   8859 C CG2 . ILE D 2 239 ? -50.047 -23.203 39.659  1   26.85  ? 409 ILE D CG2 1 
ATOM   8860 C CD1 . ILE D 2 239 ? -47.135 -23.265 38.655  1   26.43  ? 409 ILE D CD1 1 
ATOM   8861 N N   . ARG D 2 240 ? -50.643 -25.924 42.433  1   34.86  ? 410 ARG D N   1 
ATOM   8862 C CA  . ARG D 2 240 ? -51.878 -26.601 42.831  1   35.27  ? 410 ARG D CA  1 
ATOM   8863 C C   . ARG D 2 240 ? -52.306 -26.19  44.245  1   34.99  ? 410 ARG D C   1 
ATOM   8864 O O   . ARG D 2 240 ? -53.493 -25.977 44.478  1   32.17  ? 410 ARG D O   1 
ATOM   8865 C CB  . ARG D 2 240 ? -51.777 -28.13  42.716  1   31.47  ? 410 ARG D CB  1 
ATOM   8866 C CG  . ARG D 2 240 ? -51.956 -28.679 41.308  1   30.73  ? 410 ARG D CG  1 
ATOM   8867 C CD  . ARG D 2 240 ? -52.159 -30.201 41.193  1   33.54  ? 410 ARG D CD  1 
ATOM   8868 N NE  . ARG D 2 240 ? -53.451 -30.737 41.648  1   32.46  ? 410 ARG D NE  1 
ATOM   8869 C CZ  . ARG D 2 240 ? -53.63  -31.425 42.778  1   32.84  ? 410 ARG D CZ  1 
ATOM   8870 N NH1 . ARG D 2 240 ? -54.836 -31.824 43.118  1   30.73  ? 410 ARG D NH1 1 
ATOM   8871 N NH2 . ARG D 2 240 ? -52.62  -31.702 43.587  1   33.08  ? 410 ARG D NH2 1 
ATOM   8872 N N   . GLU D 2 241 ? -51.34  -26.079 45.172  1   35.85  ? 411 GLU D N   1 
ATOM   8873 C CA  . GLU D 2 241 ? -51.594 -25.643 46.54   1   37.59  ? 411 GLU D CA  1 
ATOM   8874 C C   . GLU D 2 241 ? -52.088 -24.201 46.547  1   39.54  ? 411 GLU D C   1 
ATOM   8875 O O   . GLU D 2 241 ? -53.051 -23.879 47.244  1   43.34  ? 411 GLU D O   1 
ATOM   8876 C CB  . GLU D 2 241 ? -50.344 -25.662 47.422  1   37.27  ? 411 GLU D CB  1 
ATOM   8877 C CG  . GLU D 2 241 ? -49.749 -27.054 47.597  1   44.11  ? 411 GLU D CG  1 
ATOM   8878 C CD  . GLU D 2 241 ? -50.724 -28.088 48.147  1   52.86  ? 411 GLU D CD  1 
ATOM   8879 O OE1 . GLU D 2 241 ? -51.815 -27.743 48.661  1   52.08  ? 411 GLU D OE1 1 
ATOM   8880 O OE2 . GLU D 2 241 ? -50.375 -29.282 48.044  1   59.06  ? 411 GLU D OE2 1 
ATOM   8881 N N   . LYS D 2 242 ? -51.396 -23.344 45.788  1   35.65  ? 412 LYS D N   1 
ATOM   8882 C CA  . LYS D 2 242 ? -51.748 -21.939 45.674  1   34.71  ? 412 LYS D CA  1 
ATOM   8883 C C   . LYS D 2 242 ? -53.228 -21.805 45.297  1   34.84  ? 412 LYS D C   1 
ATOM   8884 O O   . LYS D 2 242 ? -53.971 -21.075 45.952  1   40.43  ? 412 LYS D O   1 
ATOM   8885 C CB  . LYS D 2 242 ? -50.78  -21.301 44.669  1   31.96  ? 412 LYS D CB  1 
ATOM   8886 C CG  . LYS D 2 242 ? -51.02  -19.849 44.288  1   30.63  ? 412 LYS D CG  1 
ATOM   8887 C CD  . LYS D 2 242 ? -50.103 -19.38  43.167  1   32.02  ? 412 LYS D CD  1 
ATOM   8888 C CE  . LYS D 2 242 ? -50.261 -17.939 42.767  1   29.76  ? 412 LYS D CE  1 
ATOM   8889 N NZ  . LYS D 2 242 ? -49.124 -17.488 41.962  1   27.24  ? 412 LYS D NZ  1 
ATOM   8890 N N   . TYR D 2 243 ? -53.654 -22.542 44.26   1   31.23  ? 413 TYR D N   1 
ATOM   8891 C CA  . TYR D 2 243 ? -54.968 -22.373 43.649  1   33.26  ? 413 TYR D CA  1 
ATOM   8892 C C   . TYR D 2 243 ? -56.026 -23.261 44.327  1   33.27  ? 413 TYR D C   1 
ATOM   8893 O O   . TYR D 2 243 ? -57.085 -23.498 43.748  1   30.23  ? 413 TYR D O   1 
ATOM   8894 C CB  . TYR D 2 243 ? -54.86  -22.567 42.128  1   30.69  ? 413 TYR D CB  1 
ATOM   8895 C CG  . TYR D 2 243 ? -54.276 -21.378 41.375  1   30.76  ? 413 TYR D CG  1 
ATOM   8896 C CD1 . TYR D 2 243 ? -52.9   -21.205 41.245  1   30.29  ? 413 TYR D CD1 1 
ATOM   8897 C CD2 . TYR D 2 243 ? -55.103 -20.417 40.803  1   31.27  ? 413 TYR D CD2 1 
ATOM   8898 C CE1 . TYR D 2 243 ? -52.359 -20.127 40.562  1   28.61  ? 413 TYR D CE1 1 
ATOM   8899 C CE2 . TYR D 2 243 ? -54.575 -19.329 40.126  1   29.96  ? 413 TYR D CE2 1 
ATOM   8900 C CZ  . TYR D 2 243 ? -53.203 -19.188 40.005  1   29.81  ? 413 TYR D CZ  1 
ATOM   8901 O OH  . TYR D 2 243 ? -52.701 -18.103 39.354  1   33.33  ? 413 TYR D OH  1 
ATOM   8902 N N   . LYS D 2 244 ? -55.736 -23.739 45.548  1   33.06  ? 414 LYS D N   1 
ATOM   8903 C CA  . LYS D 2 244 ? -56.721 -24.375 46.41   1   36.4   ? 414 LYS D CA  1 
ATOM   8904 C C   . LYS D 2 244 ? -57.39  -23.335 47.297  1   37.57  ? 414 LYS D C   1 
ATOM   8905 O O   . LYS D 2 244 ? -58.582 -23.443 47.58   1   34.11  ? 414 LYS D O   1 
ATOM   8906 C CB  . LYS D 2 244 ? -56.088 -25.394 47.36   1   36.09  ? 414 LYS D CB  1 
ATOM   8907 C CG  . LYS D 2 244 ? -55.827 -26.758 46.741  1   36.66  ? 414 LYS D CG  1 
ATOM   8908 C CD  . LYS D 2 244 ? -55.011 -27.677 47.644  1   37.19  ? 414 LYS D CD  1 
ATOM   8909 C CE  . LYS D 2 244 ? -54.669 -28.967 46.954  1   37.54  ? 414 LYS D CE  1 
ATOM   8910 N NZ  . LYS D 2 244 ? -53.824 -29.849 47.759  1   36.82  ? 414 LYS D NZ  1 
ATOM   8911 N N   . ASN D 2 245 ? -56.592 -22.357 47.743  1   41.66  ? 415 ASN D N   1 
ATOM   8912 C CA  . ASN D 2 245 ? -57.07  -21.258 48.565  1   48.55  ? 415 ASN D CA  1 
ATOM   8913 C C   . ASN D 2 245 ? -58.309 -20.643 47.902  1   49.1   ? 415 ASN D C   1 
ATOM   8914 O O   . ASN D 2 245 ? -58.444 -20.644 46.67   1   48.9   ? 415 ASN D O   1 
ATOM   8915 C CB  . ASN D 2 245 ? -55.923 -20.312 48.919  1   53.6   ? 415 ASN D CB  1 
ATOM   8916 C CG  . ASN D 2 245 ? -56.278 -19.302 49.992  1   64.73  ? 415 ASN D CG  1 
ATOM   8917 O OD1 . ASN D 2 245 ? -57.076 -18.382 49.768  1   67.97  ? 415 ASN D OD1 1 
ATOM   8918 N ND2 . ASN D 2 245 ? -55.677 -19.437 51.166  1   70.23  ? 415 ASN D ND2 1 
ATOM   8919 N N   . SER D 2 246 ? -59.211 -20.126 48.75   1   42.52  ? 416 SER D N   1 
ATOM   8920 C CA  . SER D 2 246 ? -60.433 -19.482 48.301  1   40.12  ? 416 SER D CA  1 
ATOM   8921 C C   . SER D 2 246 ? -60.126 -18.209 47.516  1   38.59  ? 416 SER D C   1 
ATOM   8922 O O   . SER D 2 246 ? -60.932 -17.788 46.697  1   40.24  ? 416 SER D O   1 
ATOM   8923 C CB  . SER D 2 246 ? -61.378 -19.21  49.454  1   37.36  ? 416 SER D CB  1 
ATOM   8924 O OG  . SER D 2 246 ? -60.909 -18.128 50.241  1   32.76  ? 416 SER D OG  1 
ATOM   8925 N N   . LYS D 2 247 ? -58.967 -17.599 47.778  1   40.44  ? 417 LYS D N   1 
ATOM   8926 C CA  . LYS D 2 247 ? -58.496 -16.452 47.014  1   42.35  ? 417 LYS D CA  1 
ATOM   8927 C C   . LYS D 2 247 ? -58.641 -16.719 45.511  1   42.05  ? 417 LYS D C   1 
ATOM   8928 O O   . LYS D 2 247 ? -58.99  -15.804 44.768  1   39.97  ? 417 LYS D O   1 
ATOM   8929 C CB  . LYS D 2 247 ? -57.071 -16.074 47.447  1   41.45  ? 417 LYS D CB  1 
ATOM   8930 C CG  . LYS D 2 247 ? -56.405 -15.034 46.56   1   42.22  ? 417 LYS D CG  1 
ATOM   8931 C CD  . LYS D 2 247 ? -54.889 -15.076 46.643  1   49.96  ? 417 LYS D CD  1 
ATOM   8932 C CE  . LYS D 2 247 ? -54.303 -14.048 47.565  1   58.64  ? 417 LYS D CE  1 
ATOM   8933 N NZ  . LYS D 2 247 ? -54.089 -12.764 46.881  1   54.28  ? 417 LYS D NZ  1 
ATOM   8934 N N   . TYR D 2 248 ? -58.393 -17.973 45.083  1   40.98  ? 418 TYR D N   1 
ATOM   8935 C CA  . TYR D 2 248 ? -58.487 -18.384 43.685  1   38.67  ? 418 TYR D CA  1 
ATOM   8936 C C   . TYR D 2 248 ? -59.69  -19.305 43.448  1   35.49  ? 418 TYR D C   1 
ATOM   8937 O O   . TYR D 2 248 ? -59.769 -19.97  42.415  1   34     ? 418 TYR D O   1 
ATOM   8938 C CB  . TYR D 2 248 ? -57.175 -19.003 43.185  1   37.67  ? 418 TYR D CB  1 
ATOM   8939 C CG  . TYR D 2 248 ? -55.982 -18.063 43.273  1   38.68  ? 418 TYR D CG  1 
ATOM   8940 C CD1 . TYR D 2 248 ? -55.833 -17.007 42.375  1   37.37  ? 418 TYR D CD1 1 
ATOM   8941 C CD2 . TYR D 2 248 ? -55.011 -18.236 44.264  1   39.12  ? 418 TYR D CD2 1 
ATOM   8942 C CE1 . TYR D 2 248 ? -54.746 -16.147 42.47   1   40.19  ? 418 TYR D CE1 1 
ATOM   8943 C CE2 . TYR D 2 248 ? -53.928 -17.378 44.369  1   39.21  ? 418 TYR D CE2 1 
ATOM   8944 C CZ  . TYR D 2 248 ? -53.797 -16.326 43.473  1   41.63  ? 418 TYR D CZ  1 
ATOM   8945 O OH  . TYR D 2 248 ? -52.729 -15.476 43.599  1   41.09  ? 418 TYR D OH  1 
ATOM   8946 N N   . HIS D 2 249 ? -60.626 -19.335 44.401  1   34.99  ? 419 HIS D N   1 
ATOM   8947 C CA  . HIS D 2 249 ? -61.935 -19.96  44.234  1   35.59  ? 419 HIS D CA  1 
ATOM   8948 C C   . HIS D 2 249 ? -61.819 -21.484 44.26   1   33.61  ? 419 HIS D C   1 
ATOM   8949 O O   . HIS D 2 249 ? -62.72  -22.163 43.776  1   34.86  ? 419 HIS D O   1 
ATOM   8950 C CB  . HIS D 2 249 ? -62.706 -19.393 43.025  1   37.58  ? 419 HIS D CB  1 
ATOM   8951 C CG  . HIS D 2 249 ? -62.995 -17.916 43.101  1   43.92  ? 419 HIS D CG  1 
ATOM   8952 N ND1 . HIS D 2 249 ? -62.157 -16.958 42.563  1   48.81  ? 419 HIS D ND1 1 
ATOM   8953 C CD2 . HIS D 2 249 ? -64.009 -17.226 43.656  1   44.58  ? 419 HIS D CD2 1 
ATOM   8954 C CE1 . HIS D 2 249 ? -62.651 -15.741 42.784  1   47.03  ? 419 HIS D CE1 1 
ATOM   8955 N NE2 . HIS D 2 249 ? -63.773 -15.88  43.454  1   45.26  ? 419 HIS D NE2 1 
ATOM   8956 N N   . GLY D 2 250 ? -60.711 -21.995 44.828  1   32.26  ? 420 GLY D N   1 
ATOM   8957 C CA  . GLY D 2 250 ? -60.354 -23.407 44.867  1   30.25  ? 420 GLY D CA  1 
ATOM   8958 C C   . GLY D 2 250 ? -60.389 -24.121 43.51   1   30.3   ? 420 GLY D C   1 
ATOM   8959 O O   . GLY D 2 250 ? -60.7   -25.307 43.457  1   34.77  ? 420 GLY D O   1 
ATOM   8960 N N   . VAL D 2 251 ? -60.024 -23.434 42.424  1   27.52  ? 421 VAL D N   1 
ATOM   8961 C CA  . VAL D 2 251 ? -60.148 -23.967 41.071  1   27.72  ? 421 VAL D CA  1 
ATOM   8962 C C   . VAL D 2 251 ? -59.243 -25.185 40.832  1   30.83  ? 421 VAL D C   1 
ATOM   8963 O O   . VAL D 2 251 ? -59.504 -25.979 39.922  1   33.3   ? 421 VAL D O   1 
ATOM   8964 C CB  . VAL D 2 251 ? -59.935 -22.92  39.954  1   27.04  ? 421 VAL D CB  1 
ATOM   8965 C CG1 . VAL D 2 251 ? -61.106 -21.935 39.842  1   25     ? 421 VAL D CG1 1 
ATOM   8966 C CG2 . VAL D 2 251 ? -58.571 -22.222 40.052  1   24.77  ? 421 VAL D CG2 1 
ATOM   8967 N N   . SER D 2 252 ? -58.159 -25.333 41.606  1   32.1   ? 422 SER D N   1 
ATOM   8968 C CA  . SER D 2 252 ? -57.254 -26.455 41.392  1   32.77  ? 422 SER D CA  1 
ATOM   8969 C C   . SER D 2 252 ? -57.862 -27.75  41.923  1   32.65  ? 422 SER D C   1 
ATOM   8970 O O   . SER D 2 252 ? -57.334 -28.815 41.639  1   35.79  ? 422 SER D O   1 
ATOM   8971 C CB  . SER D 2 252 ? -55.865 -26.227 41.963  1   34.58  ? 422 SER D CB  1 
ATOM   8972 O OG  . SER D 2 252 ? -55.837 -26.366 43.379  1   36.44  ? 422 SER D OG  1 
ATOM   8973 N N   . LEU D 2 253 ? -58.95  -27.649 42.7    1   30.52  ? 423 LEU D N   1 
ATOM   8974 C CA  . LEU D 2 253 ? -59.674 -28.806 43.207  1   30.57  ? 423 LEU D CA  1 
ATOM   8975 C C   . LEU D 2 253 ? -60.732 -29.281 42.21   1   30.84  ? 423 LEU D C   1 
ATOM   8976 O O   . LEU D 2 253 ? -61.231 -30.391 42.351  1   32.34  ? 423 LEU D O   1 
ATOM   8977 C CB  . LEU D 2 253 ? -60.297 -28.501 44.572  1   28.91  ? 423 LEU D CB  1 
ATOM   8978 C CG  . LEU D 2 253 ? -59.329 -28.315 45.75   1   28.51  ? 423 LEU D CG  1 
ATOM   8979 C CD1 . LEU D 2 253 ? -60.066 -27.718 46.94   1   26.25  ? 423 LEU D CD1 1 
ATOM   8980 C CD2 . LEU D 2 253 ? -58.609 -29.598 46.146  1   26.99  ? 423 LEU D CD2 1 
ATOM   8981 N N   . LEU D 2 254 ? -61.073 -28.446 41.218  1   32.71  ? 424 LEU D N   1 
ATOM   8982 C CA  . LEU D 2 254 ? -61.979 -28.82  40.139  1   33.95  ? 424 LEU D CA  1 
ATOM   8983 C C   . LEU D 2 254 ? -61.378 -29.966 39.334  1   37.11  ? 424 LEU D C   1 
ATOM   8984 O O   . LEU D 2 254 ? -60.193 -29.953 38.998  1   43.81  ? 424 LEU D O   1 
ATOM   8985 C CB  . LEU D 2 254 ? -62.307 -27.648 39.213  1   31.84  ? 424 LEU D CB  1 
ATOM   8986 C CG  . LEU D 2 254 ? -63.177 -26.518 39.778  1   31.62  ? 424 LEU D CG  1 
ATOM   8987 C CD1 . LEU D 2 254 ? -63.503 -25.496 38.696  1   30.32  ? 424 LEU D CD1 1 
ATOM   8988 C CD2 . LEU D 2 254 ? -64.457 -27.035 40.428  1   28.99  ? 424 LEU D CD2 1 
ATOM   8989 N N   . ASN D 2 255 ? -62.226 -30.946 39.01   1   39.22  ? 425 ASN D N   1 
ATOM   8990 C CA  . ASN D 2 255 ? -61.841 -32.079 38.189  1   41.4   ? 425 ASN D CA  1 
ATOM   8991 C C   . ASN D 2 255 ? -61.82  -31.639 36.731  1   41.57  ? 425 ASN D C   1 
ATOM   8992 O O   . ASN D 2 255 ? -62.805 -31.085 36.235  1   41.18  ? 425 ASN D O   1 
ATOM   8993 C CB  . ASN D 2 255 ? -62.744 -33.29  38.406  1   40.31  ? 425 ASN D CB  1 
ATOM   8994 C CG  . ASN D 2 255 ? -62.643 -33.8   39.822  1   44.32  ? 425 ASN D CG  1 
ATOM   8995 O OD1 . ASN D 2 255 ? -63.67  -33.986 40.484  1   46.27  ? 425 ASN D OD1 1 
ATOM   8996 N ND2 . ASN D 2 255 ? -61.421 -34     40.304  1   44.57  ? 425 ASN D ND2 1 
ATOM   8997 N N   . PRO D 2 256 ? -60.694 -31.899 36.023  1   35.24  ? 426 PRO D N   1 
ATOM   8998 C CA  . PRO D 2 256 ? -60.59  -31.596 34.593  1   33.35  ? 426 PRO D CA  1 
ATOM   8999 C C   . PRO D 2 256 ? -61.549 -32.391 33.705  1   33.24  ? 426 PRO D C   1 
ATOM   9000 O O   . PRO D 2 256 ? -61.811 -33.564 33.971  1   30.57  ? 426 PRO D O   1 
ATOM   9001 C CB  . PRO D 2 256 ? -59.135 -31.941 34.268  1   34.82  ? 426 PRO D CB  1 
ATOM   9002 C CG  . PRO D 2 256 ? -58.697 -32.904 35.36   1   35.12  ? 426 PRO D CG  1 
ATOM   9003 C CD  . PRO D 2 256 ? -59.479 -32.508 36.589  1   33.03  ? 426 PRO D CD  1 
ATOM   9004 N N   . PRO D 2 257 ? -62.048 -31.803 32.588  1   34.62  ? 427 PRO D N   1 
ATOM   9005 C CA  . PRO D 2 257 ? -62.812 -32.549 31.583  1   35.82  ? 427 PRO D CA  1 
ATOM   9006 C C   . PRO D 2 257 ? -61.921 -33.643 31.007  1   38.55  ? 427 PRO D C   1 
ATOM   9007 O O   . PRO D 2 257 ? -60.703 -33.476 30.925  1   42.51  ? 427 PRO D O   1 
ATOM   9008 C CB  . PRO D 2 257 ? -63.134 -31.479 30.517  1   35.83  ? 427 PRO D CB  1 
ATOM   9009 C CG  . PRO D 2 257 ? -62.023 -30.461 30.689  1   35.21  ? 427 PRO D CG  1 
ATOM   9010 C CD  . PRO D 2 257 ? -61.838 -30.4   32.198  1   34.77  ? 427 PRO D CD  1 
ATOM   9011 N N   . GLU D 2 258 ? -62.538 -34.754 30.603  1   40.19  ? 428 GLU D N   1 
ATOM   9012 C CA  . GLU D 2 258 ? -61.782 -35.9   30.128  1   41.64  ? 428 GLU D CA  1 
ATOM   9013 C C   . GLU D 2 258 ? -61.508 -35.798 28.624  1   41.75  ? 428 GLU D C   1 
ATOM   9014 O O   . GLU D 2 258 ? -60.551 -36.397 28.137  1   42.06  ? 428 GLU D O   1 
ATOM   9015 C CB  . GLU D 2 258 ? -62.42  -37.205 30.604  1   42.29  ? 428 GLU D CB  1 
ATOM   9016 C CG  . GLU D 2 258 ? -61.815 -37.731 31.906  1   43.07  ? 428 GLU D CG  1 
ATOM   9017 C CD  . GLU D 2 258 ? -62.501 -38.972 32.463  1   48.41  ? 428 GLU D CD  1 
ATOM   9018 O OE1 . GLU D 2 258 ? -62.705 -39.955 31.714  1   48.72  ? 428 GLU D OE1 1 
ATOM   9019 O OE2 . GLU D 2 258 ? -62.832 -38.967 33.668  1   48.72  ? 428 GLU D OE2 1 
ATOM   9020 N N   . THR D 2 259 ? -62.356 -35.062 27.887  1   39.41  ? 429 THR D N   1 
ATOM   9021 C CA  . THR D 2 259 ? -62.131 -34.78  26.47   1   39.26  ? 429 THR D CA  1 
ATOM   9022 C C   . THR D 2 259 ? -62.616 -33.375 26.131  1   41.9   ? 429 THR D C   1 
ATOM   9023 O O   . THR D 2 259 ? -63.441 -32.814 26.853  1   42.44  ? 429 THR D O   1 
ATOM   9024 C CB  . THR D 2 259 ? -62.796 -35.78  25.522  1   39.64  ? 429 THR D CB  1 
ATOM   9025 O OG1 . THR D 2 259 ? -64.214 -35.674 25.664  1   39.08  ? 429 THR D OG1 1 
ATOM   9026 C CG2 . THR D 2 259 ? -62.253 -37.193 25.65   1   38.23  ? 429 THR D CG2 1 
ATOM   9027 N N   . LEU D 2 260 ? -62.143 -32.857 24.986  1   44.75  ? 430 LEU D N   1 
ATOM   9028 C CA  . LEU D 2 260 ? -62.414 -31.486 24.576  1   48.48  ? 430 LEU D CA  1 
ATOM   9029 C C   . LEU D 2 260 ? -63.36  -31.407 23.373  1   51.05  ? 430 LEU D C   1 
ATOM   9030 O O   . LEU D 2 260 ? -63.798 -30.311 23.025  1   52.94  ? 430 LEU D O   1 
ATOM   9031 C CB  . LEU D 2 260 ? -61.083 -30.8   24.281  1   41.5   ? 430 LEU D CB  1 
ATOM   9032 C CG  . LEU D 2 260 ? -60.01  -31     25.352  1   44.97  ? 430 LEU D CG  1 
ATOM   9033 C CD1 . LEU D 2 260 ? -58.659 -30.518 24.864  1   45.59  ? 430 LEU D CD1 1 
ATOM   9034 C CD2 . LEU D 2 260 ? -60.392 -30.332 26.666  1   43.83  ? 430 LEU D CD2 1 
ATOM   9035 N N   . ASN D 2 261 ? -63.666 -32.545 22.733  1   51.81  ? 431 ASN D N   1 
ATOM   9036 C CA  . ASN D 2 261 ? -64.554 -32.569 21.574  1   58.84  ? 431 ASN D CA  1 
ATOM   9037 C C   . ASN D 2 261 ? -64.04  -31.624 20.482  1   61.81  ? 431 ASN D C   1 
ATOM   9038 O O   . ASN D 2 261 ? -64.762 -30.715 20.064  1   62.47  ? 431 ASN D O   1 
ATOM   9039 C CB  . ASN D 2 261 ? -65.986 -32.157 21.929  1   61.38  ? 431 ASN D CB  1 
ATOM   9040 C CG  . ASN D 2 261 ? -66.582 -32.927 23.085  1   63.91  ? 431 ASN D CG  1 
ATOM   9041 O OD1 . ASN D 2 261 ? -66.015 -32.943 24.187  1   75.33  ? 431 ASN D OD1 1 
ATOM   9042 N ND2 . ASN D 2 261 ? -67.724 -33.556 22.852  1   54.51  ? 431 ASN D ND2 1 
ATOM   9043 N N   . VAL D 2 262 ? -62.801 -31.848 20.017  1   64.39  ? 432 VAL D N   1 
ATOM   9044 C CA  . VAL D 2 262 ? -62.168 -30.961 19.046  1   65.14  ? 432 VAL D CA  1 
ATOM   9045 C C   . VAL D 2 262 ? -61.875 -31.708 17.733  1   66.95  ? 432 VAL D C   1 
ATOM   9046 O O   . VAL D 2 262 ? -62.432 -32.809 17.564  1   71.78  ? 432 VAL D O   1 
ATOM   9047 C CB  . VAL D 2 262 ? -60.873 -30.355 19.611  1   65.93  ? 432 VAL D CB  1 
ATOM   9048 C CG1 . VAL D 2 262 ? -61.157 -29.342 20.718  1   59.73  ? 432 VAL D CG1 1 
ATOM   9049 C CG2 . VAL D 2 262 ? -59.912 -31.453 20.062  1   68.81  ? 432 VAL D CG2 1 
HETATM 9050 C C4  . IJL E 3 .   ? 13.44   -23.679 -7.562  0.8 65.85  ? 301 IJL A C4  1 
HETATM 9051 C C5  . IJL E 3 .   ? 14.135  -24.884 -7.664  0.8 72.28  ? 301 IJL A C5  1 
HETATM 9052 C C6  . IJL E 3 .   ? 14.972  -25.295 -6.614  0.8 66.94  ? 301 IJL A C6  1 
HETATM 9053 C C7  . IJL E 3 .   ? 15.117  -24.492 -5.484  0.8 60.84  ? 301 IJL A C7  1 
HETATM 9054 N N1  . IJL E 3 .   ? 13.503  -21.484 -4.089  0.8 63.57  ? 301 IJL A N1  1 
HETATM 9055 C C3  . IJL E 3 .   ? 13.576  -22.901 -6.418  0.8 63.5   ? 301 IJL A C3  1 
HETATM 9056 C C1  . IJL E 3 .   ? 14.464  -22.389 -4.19   0.8 57.3   ? 301 IJL A C1  1 
HETATM 9057 O O1  . IJL E 3 .   ? 15.363  -22.486 -3.347  0.8 49.13  ? 301 IJL A O1  1 
HETATM 9058 C C2  . IJL E 3 .   ? 14.423  -23.289 -5.382  0.8 64.35  ? 301 IJL A C2  1 
HETATM 9059 I I1  . IJL E 3 .   ? 13.925  -26.067 -9.422  0.8 83.47  ? 301 IJL A I1  1 
HETATM 9060 C C4  A IJL F 3 .   ? -6.706  -20.894 22.733  0.5 43.52  ? 302 IJL A C4  1 
HETATM 9061 C C4  B IJL F 3 .   ? -7.48   -20.997 23.114  0.5 125.4  ? 302 IJL A C4  1 
HETATM 9062 C C5  A IJL F 3 .   ? -5.701  -21.567 23.404  0.5 54.3   ? 302 IJL A C5  1 
HETATM 9063 C C5  B IJL F 3 .   ? -7.7    -19.997 22.189  0.5 113.1  ? 302 IJL A C5  1 
HETATM 9064 C C6  A IJL F 3 .   ? -6.019  -22.499 24.396  0.5 43.42  ? 302 IJL A C6  1 
HETATM 9065 C C6  B IJL F 3 .   ? -6.657  -19.33  21.594  0.5 113.08 ? 302 IJL A C6  1 
HETATM 9066 C C7  A IJL F 3 .   ? -7.352  -22.744 24.7    0.5 34.07  ? 302 IJL A C7  1 
HETATM 9067 C C7  B IJL F 3 .   ? -5.367  -19.673 21.927  0.5 133.61 ? 302 IJL A C7  1 
HETATM 9068 N N1  A IJL F 3 .   ? -10.746 -21.821 23.554  0.5 22.38  ? 302 IJL A N1  1 
HETATM 9069 N N1  B IJL F 3 .   ? -2.787  -20.143 22.816  0.5 168.9  ? 302 IJL A N1  1 
HETATM 9070 C C3  A IJL F 3 .   ? -8.025  -21.147 23.056  0.5 37.9   ? 302 IJL A C3  1 
HETATM 9071 C C3  B IJL F 3 .   ? -6.187  -21.356 23.424  0.5 141.71 ? 302 IJL A C3  1 
HETATM 9072 C C1  A IJL F 3 .   ? -9.807  -22.337 24.34   0.5 25.97  ? 302 IJL A C1  1 
HETATM 9073 C C1  B IJL F 3 .   ? -3.715  -21.019 23.174  0.5 166.39 ? 302 IJL A C1  1 
HETATM 9074 O O1  A IJL F 3 .   ? -10.092 -23.054 25.301  0.5 25.74  ? 302 IJL A O1  1 
HETATM 9075 O O1  B IJL F 3 .   ? -3.449  -22.102 23.719  0.5 175.72 ? 302 IJL A O1  1 
HETATM 9076 C C2  A IJL F 3 .   ? -8.367  -22.059 24.046  0.5 31.06  ? 302 IJL A C2  1 
HETATM 9077 C C2  B IJL F 3 .   ? -5.125  -20.675 22.852  0.5 151.61 ? 302 IJL A C2  1 
HETATM 9078 I I1  A IJL F 3 .   ? -3.686  -21.177 22.88   0.5 92.22  ? 302 IJL A I1  1 
HETATM 9079 I I1  B IJL F 3 .   ? -9.659  -19.492 21.667  0.5 101.5  ? 302 IJL A I1  1 
HETATM 9080 C C4  . IJL G 3 .   ? -32.527 16.743  28.447  1   60.33  ? 301 IJL C C4  1 
HETATM 9081 C C5  . IJL G 3 .   ? -32.669 16.233  29.757  1   82.63  ? 301 IJL C C5  1 
HETATM 9082 C C6  . IJL G 3 .   ? -32.703 17.097  30.862  1   65.75  ? 301 IJL C C6  1 
HETATM 9083 C C7  . IJL G 3 .   ? -32.559 18.456  30.652  1   63.99  ? 301 IJL C C7  1 
HETATM 9084 N N1  . IJL G 3 .   ? -31.358 20.918  28.426  1   100.06 ? 301 IJL C N1  1 
HETATM 9085 C C3  . IJL G 3 .   ? -32.374 18.109  28.266  1   53.72  ? 301 IJL C C3  1 
HETATM 9086 C C1  . IJL G 3 .   ? -32.262 20.452  29.276  1   84.69  ? 301 IJL C C1  1 
HETATM 9087 O O1  . IJL G 3 .   ? -33.028 21.214  29.888  1   79.7   ? 301 IJL C O1  1 
HETATM 9088 C C2  . IJL G 3 .   ? -32.451 18.971  29.363  1   70.92  ? 301 IJL C C2  1 
HETATM 9089 I I1  . IJL G 3 .   ? -32.941 14.153  30.084  1   121.72 ? 301 IJL C I1  1 
HETATM 9090 O O   . HOH H 4 .   ? 4.934   -19.551 -4.848  1   28.73  ? 401 HOH A O   1 
HETATM 9091 O O   . HOH H 4 .   ? -13.846 -36.18  -4.838  1   59.68  ? 402 HOH A O   1 
HETATM 9092 O O   . HOH H 4 .   ? -14.853 -11.943 -5.155  1   17.07  ? 403 HOH A O   1 
HETATM 9093 O O   . HOH H 4 .   ? -2.853  -12.951 6.223   1   33.65  ? 404 HOH A O   1 
HETATM 9094 O O   . HOH H 4 .   ? 3.832   -20.613 -0.86   1   31.48  ? 405 HOH A O   1 
HETATM 9095 O O   . HOH H 4 .   ? -0.866  -24.988 -18.61  1   36.87  ? 406 HOH A O   1 
HETATM 9096 O O   . HOH H 4 .   ? -17.082 -22.343 27.975  1   23.81  ? 407 HOH A O   1 
HETATM 9097 O O   . HOH H 4 .   ? 1.095   5.011   10.566  1   25.78  ? 408 HOH A O   1 
HETATM 9098 O O   . HOH H 4 .   ? -13.334 -11.569 -3.038  1   27.03  ? 409 HOH A O   1 
HETATM 9099 O O   . HOH H 4 .   ? 2.104   -32.369 6.195   1   21.13  ? 410 HOH A O   1 
HETATM 9100 O O   . HOH H 4 .   ? -12.113 -12.744 -9.195  1   22.69  ? 411 HOH A O   1 
HETATM 9101 O O   . HOH H 4 .   ? 5.4     -20.569 -15.068 1   28.5   ? 412 HOH A O   1 
HETATM 9102 O O   . HOH H 4 .   ? -7.625  -16.6   -3.882  1   19.87  ? 413 HOH A O   1 
HETATM 9103 O O   . HOH H 4 .   ? 2.265   -29.552 13.206  1   38.27  ? 414 HOH A O   1 
HETATM 9104 O O   . HOH H 4 .   ? 15.454  -31.147 -14.219 1   16.16  ? 415 HOH A O   1 
HETATM 9105 O O   . HOH H 4 .   ? -22.191 -18.674 27.844  1   24.66  ? 416 HOH A O   1 
HETATM 9106 O O   . HOH H 4 .   ? -22.034 -17.68  31.477  1   10.01  ? 417 HOH A O   1 
HETATM 9107 O O   . HOH H 4 .   ? -19.964 -14.878 42.65   1   31.9   ? 418 HOH A O   1 
HETATM 9108 O O   . HOH H 4 .   ? 1.197   -29.532 2.266   1   18.36  ? 419 HOH A O   1 
HETATM 9109 O O   . HOH H 4 .   ? 1.997   -18.466 6.381   1   35.87  ? 420 HOH A O   1 
HETATM 9110 O O   . HOH H 4 .   ? -19.279 -21.402 17.271  1   30.63  ? 421 HOH A O   1 
HETATM 9111 O O   . HOH H 4 .   ? 5.518   -41.795 1.088   1   27.55  ? 422 HOH A O   1 
HETATM 9112 O O   . HOH H 4 .   ? -14.119 -27.08  -1.396  1   24.32  ? 423 HOH A O   1 
HETATM 9113 O O   . HOH H 4 .   ? -15.257 -38.163 19.705  1   35.9   ? 424 HOH A O   1 
HETATM 9114 O O   . HOH H 4 .   ? -6.896  -12.869 8.451   1   24.32  ? 425 HOH A O   1 
HETATM 9115 O O   . HOH H 4 .   ? 0.261   -33.588 8.312   1   19.47  ? 426 HOH A O   1 
HETATM 9116 O O   . HOH H 4 .   ? -22.868 -26.796 4.726   1   43.28  ? 427 HOH A O   1 
HETATM 9117 O O   . HOH H 4 .   ? -23.078 -34.574 2.303   1   31.63  ? 428 HOH A O   1 
HETATM 9118 O O   . HOH H 4 .   ? 1.248   -38.435 8.071   1   29.05  ? 429 HOH A O   1 
HETATM 9119 O O   . HOH H 4 .   ? -3.608  -25.59  2.429   1   25.86  ? 430 HOH A O   1 
HETATM 9120 O O   . HOH H 4 .   ? -1.801  -43.814 -6.931  1   56.64  ? 431 HOH A O   1 
HETATM 9121 O O   . HOH H 4 .   ? -4.568  -9.19   8.183   1   29.09  ? 432 HOH A O   1 
HETATM 9122 O O   . HOH H 4 .   ? 5.376   -32.011 -14.672 1   33.7   ? 433 HOH A O   1 
HETATM 9123 O O   . HOH H 4 .   ? -14.051 -46.299 -0.618  1   34.97  ? 434 HOH A O   1 
HETATM 9124 O O   . HOH H 4 .   ? -19.13  -24.535 19.56   1   21.57  ? 435 HOH A O   1 
HETATM 9125 O O   . HOH H 4 .   ? -4.361  -8.436  5.431   1   34.26  ? 436 HOH A O   1 
HETATM 9126 O O   . HOH H 4 .   ? -3.201  -4.691  11.338  1   25.31  ? 437 HOH A O   1 
HETATM 9127 O O   . HOH H 4 .   ? -4.424  -19.377 -10.242 1   19.54  ? 438 HOH A O   1 
HETATM 9128 O O   . HOH H 4 .   ? -16.496 -43.725 14.958  1   31.2   ? 439 HOH A O   1 
HETATM 9129 O O   . HOH H 4 .   ? -18.254 -18.256 17.126  1   33.52  ? 440 HOH A O   1 
HETATM 9130 O O   . HOH H 4 .   ? 4.349   -17.085 4.507   1   53.78  ? 441 HOH A O   1 
HETATM 9131 O O   . HOH H 4 .   ? -9.157  -46.832 -1.961  1   38.32  ? 442 HOH A O   1 
HETATM 9132 O O   . HOH H 4 .   ? -7.408  -18.441 10.597  1   19.8   ? 443 HOH A O   1 
HETATM 9133 O O   . HOH H 4 .   ? -7.853  -23.65  -4.187  1   30.1   ? 444 HOH A O   1 
HETATM 9134 O O   . HOH H 4 .   ? -3.056  -5.792  7.586   1   40.72  ? 445 HOH A O   1 
HETATM 9135 O O   . HOH H 4 .   ? -3.978  -51.484 5.658   1   39.31  ? 446 HOH A O   1 
HETATM 9136 O O   . HOH H 4 .   ? -16.154 -23.18  37.348  1   24.83  ? 447 HOH A O   1 
HETATM 9137 O O   . HOH H 4 .   ? -16.713 -32.614 -3.84   1   28.15  ? 448 HOH A O   1 
HETATM 9138 O O   . HOH H 4 .   ? -26.94  -20.079 8.294   1   33.62  ? 449 HOH A O   1 
HETATM 9139 O O   . HOH H 4 .   ? 2.313   -54.076 -1.46   1   30.9   ? 450 HOH A O   1 
HETATM 9140 O O   . HOH H 4 .   ? 0.385   -37.022 -9.89   1   25.67  ? 451 HOH A O   1 
HETATM 9141 O O   . HOH H 4 .   ? -26.733 -27.050 0.522   1   39.38  ? 452 HOH A O   1 
HETATM 9142 O O   . HOH H 4 .   ? -8.856  -12.359 37.957  1   17.89  ? 453 HOH A O   1 
HETATM 9143 O O   . HOH H 4 .   ? 9.482   -22.299 -7.906  1   32.4   ? 454 HOH A O   1 
HETATM 9144 O O   . HOH H 4 .   ? 10.471  -37.123 0.645   1   38.08  ? 455 HOH A O   1 
HETATM 9145 O O   . HOH H 4 .   ? -2.59   -7.572  12.071  1   29.63  ? 456 HOH A O   1 
HETATM 9146 O O   . HOH H 4 .   ? -15.851 -41.54  -2.801  1   24.99  ? 457 HOH A O   1 
HETATM 9147 O O   . HOH H 4 .   ? -21.986 -28.298 8.204   1   36.57  ? 458 HOH A O   1 
HETATM 9148 O O   . HOH H 4 .   ? -16.544 -26.383 25.723  1   41.57  ? 459 HOH A O   1 
HETATM 9149 O O   . HOH H 4 .   ? 1.718   -50.832 2.31    1   31.31  ? 460 HOH A O   1 
HETATM 9150 O O   . HOH H 4 .   ? -10.204 -10.922 -9.593  1   23.27  ? 461 HOH A O   1 
HETATM 9151 O O   . HOH H 4 .   ? 4.737   -21.887 8.21    1   25.58  ? 462 HOH A O   1 
HETATM 9152 O O   . HOH H 4 .   ? 3.186   -40.311 7.251   1   40.29  ? 463 HOH A O   1 
HETATM 9153 O O   . HOH H 4 .   ? -2.453  -18.907 -11.714 1   31.02  ? 464 HOH A O   1 
HETATM 9154 O O   . HOH H 4 .   ? -23.418 -29.478 10.423  1   21.02  ? 465 HOH A O   1 
HETATM 9155 O O   . HOH H 4 .   ? -8.585  -48.897 16.119  1   29.89  ? 466 HOH A O   1 
HETATM 9156 O O   . HOH H 4 .   ? 4.248   -40.99  3.285   1   23.59  ? 467 HOH A O   1 
HETATM 9157 O O   . HOH H 4 .   ? 11.829  -22.081 -1.362  1   44.62  ? 468 HOH A O   1 
HETATM 9158 O O   . HOH H 4 .   ? -17.462 -4.212  26.264  1   64.38  ? 469 HOH A O   1 
HETATM 9159 O O   . HOH H 4 .   ? -12.813 -50.016 4.371   1   17.36  ? 470 HOH A O   1 
HETATM 9160 O O   . HOH H 4 .   ? 13.419  -34.86  7.41    1   30.61  ? 471 HOH A O   1 
HETATM 9161 O O   . HOH H 4 .   ? -4.266  -35.931 -8.184  1   26.36  ? 472 HOH A O   1 
HETATM 9162 O O   . HOH H 4 .   ? 2.75    -24.922 13.993  1   33.17  ? 473 HOH A O   1 
HETATM 9163 O O   . HOH H 4 .   ? -3.636  -51.921 8.745   1   34.59  ? 474 HOH A O   1 
HETATM 9164 O O   . HOH H 4 .   ? -2.188  -8.814  8.747   1   27.26  ? 475 HOH A O   1 
HETATM 9165 O O   . HOH H 4 .   ? -15.842 -43.93  -1.926  1   29.44  ? 476 HOH A O   1 
HETATM 9166 O O   . HOH H 4 .   ? -24.441 -27.306 10.236  1   22.51  ? 477 HOH A O   1 
HETATM 9167 O O   . HOH H 4 .   ? -4.149  -11.921 8.803   1   23.96  ? 478 HOH A O   1 
HETATM 9168 O O   . HOH H 4 .   ? 10.609  -41.493 -9.962  1   38.7   ? 479 HOH A O   1 
HETATM 9169 O O   . HOH H 4 .   ? -7.909  -51.449 6.501   1   34.28  ? 480 HOH A O   1 
HETATM 9170 O O   . HOH H 4 .   ? 5.753   -44.467 9.477   1   36.89  ? 481 HOH A O   1 
HETATM 9171 O O   . HOH H 4 .   ? -6.177  -52.125 4.277   1   31.44  ? 482 HOH A O   1 
HETATM 9172 O O   . HOH H 4 .   ? 5.493   -25.888 9.384   1   34.31  ? 483 HOH A O   1 
HETATM 9173 O O   . HOH H 4 .   ? 8.231   -25.219 8.921   1   39.23  ? 484 HOH A O   1 
HETATM 9174 O O   . HOH H 4 .   ? 12.901  -36.301 2.442   1   36.3   ? 485 HOH A O   1 
HETATM 9175 O O   . HOH H 4 .   ? -0.268  -54.001 -0.713  1   30.04  ? 486 HOH A O   1 
HETATM 9176 O O   . HOH H 4 .   ? -3.304  -21.768 -17.787 1   40.92  ? 487 HOH A O   1 
HETATM 9177 O O   . HOH H 4 .   ? -8.338  -23.689 -9.648  1   46.34  ? 488 HOH A O   1 
HETATM 9178 O O   . HOH H 4 .   ? -24.723 -24.288 6.616   1   43.51  ? 489 HOH A O   1 
HETATM 9179 O O   . HOH H 4 .   ? -13.304 -26.707 32.911  1   49.21  ? 490 HOH A O   1 
HETATM 9180 O O   . HOH H 4 .   ? -0.055  -13.936 5.991   1   41.31  ? 491 HOH A O   1 
HETATM 9181 O O   . HOH H 4 .   ? -27.327 -21.845 10.912  1   28.69  ? 492 HOH A O   1 
HETATM 9182 O O   . HOH I 4 .   ? -13.493 -10.835 -0.322  1   24.22  ? 501 HOH B O   1 
HETATM 9183 O O   . HOH I 4 .   ? -28.854 9.662   -8.373  1   25.48  ? 502 HOH B O   1 
HETATM 9184 O O   . HOH I 4 .   ? -17.642 -0.919  -7.703  1   26.54  ? 503 HOH B O   1 
HETATM 9185 O O   . HOH I 4 .   ? -22.853 11.179  17.903  1   13.06  ? 504 HOH B O   1 
HETATM 9186 O O   . HOH I 4 .   ? -24.144 -4.496  14.387  1   32.98  ? 505 HOH B O   1 
HETATM 9187 O O   . HOH I 4 .   ? -30.057 -21.789 -0.201  1   26.55  ? 506 HOH B O   1 
HETATM 9188 O O   . HOH I 4 .   ? -32.362 -10.157 0.772   1   18.77  ? 507 HOH B O   1 
HETATM 9189 O O   . HOH I 4 .   ? -27.086 12.646  -3.399  1   30.22  ? 508 HOH B O   1 
HETATM 9190 O O   . HOH I 4 .   ? -8.517  2.225   17.199  1   32.44  ? 509 HOH B O   1 
HETATM 9191 O O   . HOH I 4 .   ? -25.915 4.005   18.516  1   32.74  ? 510 HOH B O   1 
HETATM 9192 O O   . HOH I 4 .   ? -25.851 11.039  -0.553  1   25.78  ? 511 HOH B O   1 
HETATM 9193 O O   . HOH I 4 .   ? -16.894 -8.019  -3.852  1   36.73  ? 512 HOH B O   1 
HETATM 9194 O O   . HOH I 4 .   ? -21.257 4.863   -19.644 1   32.13  ? 513 HOH B O   1 
HETATM 9195 O O   . HOH I 4 .   ? -16.006 -8.09   1.772   1   27.88  ? 514 HOH B O   1 
HETATM 9196 O O   . HOH I 4 .   ? -16.329 14.945  -8.236  1   26.21  ? 515 HOH B O   1 
HETATM 9197 O O   . HOH I 4 .   ? -19.472 -13.042 -0.513  1   25.49  ? 516 HOH B O   1 
HETATM 9198 O O   . HOH I 4 .   ? -33.137 16.838  11.832  1   60.72  ? 517 HOH B O   1 
HETATM 9199 O O   . HOH I 4 .   ? -12.137 4.107   -5.696  1   33.6   ? 518 HOH B O   1 
HETATM 9200 O O   . HOH I 4 .   ? -5.683  -6.104  6.061   1   15.11  ? 519 HOH B O   1 
HETATM 9201 O O   . HOH I 4 .   ? -34.477 -2.882  -20.554 1   39.05  ? 520 HOH B O   1 
HETATM 9202 O O   . HOH I 4 .   ? -20.031 9.404   -20.834 1   32.25  ? 521 HOH B O   1 
HETATM 9203 O O   . HOH I 4 .   ? -20.862 8.457   -17.659 1   16.91  ? 522 HOH B O   1 
HETATM 9204 O O   . HOH I 4 .   ? -15.107 -27.411 1.292   1   13.62  ? 523 HOH B O   1 
HETATM 9205 O O   . HOH I 4 .   ? -4.2    -4.581  -0.709  1   35.57  ? 524 HOH B O   1 
HETATM 9206 O O   . HOH I 4 .   ? -6.066  -3.407  -3.754  1   23.79  ? 525 HOH B O   1 
HETATM 9207 O O   . HOH I 4 .   ? -12.435 -10.166 3.147   1   29.74  ? 526 HOH B O   1 
HETATM 9208 O O   . HOH I 4 .   ? -19.062 10.021  -11.163 1   18.35  ? 527 HOH B O   1 
HETATM 9209 O O   . HOH I 4 .   ? -33.772 1.309   -25.848 1   26.98  ? 528 HOH B O   1 
HETATM 9210 O O   . HOH I 4 .   ? -26.114 15.763  11.891  1   32.01  ? 529 HOH B O   1 
HETATM 9211 O O   . HOH I 4 .   ? -15.523 14.663  -3.003  1   36.96  ? 530 HOH B O   1 
HETATM 9212 O O   . HOH I 4 .   ? -24.114 -17.395 -9.23   1   39.17  ? 531 HOH B O   1 
HETATM 9213 O O   . HOH I 4 .   ? -27.125 6.305   19.518  1   29.74  ? 532 HOH B O   1 
HETATM 9214 O O   . HOH I 4 .   ? -38.478 4.241   -9.431  1   24.07  ? 533 HOH B O   1 
HETATM 9215 O O   . HOH I 4 .   ? -23.381 20.371  0.658   1   26.13  ? 534 HOH B O   1 
HETATM 9216 O O   . HOH I 4 .   ? -18.718 10.262  -8.364  1   21.19  ? 535 HOH B O   1 
HETATM 9217 O O   . HOH I 4 .   ? -29.144 11.735  14.009  1   26.99  ? 536 HOH B O   1 
HETATM 9218 O O   . HOH I 4 .   ? -17.745 -12.92  -11.736 1   25.76  ? 537 HOH B O   1 
HETATM 9219 O O   . HOH I 4 .   ? -21.516 11.349  -11.8   1   23     ? 538 HOH B O   1 
HETATM 9220 O O   . HOH I 4 .   ? -27.575 -3.894  3.165   1   34.39  ? 539 HOH B O   1 
HETATM 9221 O O   . HOH I 4 .   ? -32.399 17.065  8.935   1   30.49  ? 540 HOH B O   1 
HETATM 9222 O O   . HOH I 4 .   ? 0.471   11.526  8.279   1   24.93  ? 541 HOH B O   1 
HETATM 9223 O O   . HOH I 4 .   ? -30.177 -11.778 -4.913  1   30.49  ? 542 HOH B O   1 
HETATM 9224 O O   . HOH I 4 .   ? -24.325 9.336   -8.504  1   19.95  ? 543 HOH B O   1 
HETATM 9225 O O   . HOH I 4 .   ? -11.567 9.454   -9.471  1   24.76  ? 544 HOH B O   1 
HETATM 9226 O O   . HOH I 4 .   ? -24.833 -24.268 -1.64   1   24.59  ? 545 HOH B O   1 
HETATM 9227 O O   . HOH I 4 .   ? -15.82  16.612  7.817   1   24.36  ? 546 HOH B O   1 
HETATM 9228 O O   . HOH I 4 .   ? -25.723 20.609  2.247   1   23.11  ? 547 HOH B O   1 
HETATM 9229 O O   . HOH I 4 .   ? -32.466 8.578   -10.078 1   28.62  ? 548 HOH B O   1 
HETATM 9230 O O   . HOH I 4 .   ? -28.579 -23.659 -0.671  1   36.85  ? 549 HOH B O   1 
HETATM 9231 O O   . HOH I 4 .   ? -36.558 -13.048 -3.796  1   30.09  ? 550 HOH B O   1 
HETATM 9232 O O   . HOH I 4 .   ? -20.441 -22.221 -9.189  1   39.02  ? 551 HOH B O   1 
HETATM 9233 O O   . HOH I 4 .   ? -12.575 -22.179 -10.764 1   39.51  ? 552 HOH B O   1 
HETATM 9234 O O   . HOH I 4 .   ? -32.766 -16.459 -3.414  1   29.76  ? 553 HOH B O   1 
HETATM 9235 O O   . HOH I 4 .   ? -24.013 -24.179 -4.151  1   32.4   ? 554 HOH B O   1 
HETATM 9236 O O   . HOH I 4 .   ? -37.866 -10.723 -15.569 1   15.02  ? 555 HOH B O   1 
HETATM 9237 O O   . HOH I 4 .   ? -23.61  -25.156 -8.298  1   24.18  ? 556 HOH B O   1 
HETATM 9238 O O   . HOH I 4 .   ? -11.477 -3.736  -7.173  1   39.42  ? 557 HOH B O   1 
HETATM 9239 O O   . HOH I 4 .   ? -32.42  -11.419 -23.059 1   36.01  ? 558 HOH B O   1 
HETATM 9240 O O   . HOH I 4 .   ? -19.662 -9.212  10.462  1   34.9   ? 559 HOH B O   1 
HETATM 9241 O O   . HOH I 4 .   ? -13.401 19.059  13.471  1   21.34  ? 560 HOH B O   1 
HETATM 9242 O O   . HOH I 4 .   ? -27.467 2.239   -0.788  1   29.51  ? 561 HOH B O   1 
HETATM 9243 O O   . HOH I 4 .   ? -13.062 -5.26   -5.351  1   23.47  ? 562 HOH B O   1 
HETATM 9244 O O   . HOH I 4 .   ? -8.028  -22.67  -6.92   1   55.72  ? 563 HOH B O   1 
HETATM 9245 O O   . HOH I 4 .   ? -29.728 -12.862 -20.848 1   33.87  ? 564 HOH B O   1 
HETATM 9246 O O   . HOH I 4 .   ? -36.934 -2.242  -7.309  1   31.41  ? 565 HOH B O   1 
HETATM 9247 O O   . HOH I 4 .   ? -23.141 -10.786 -20.502 1   38.32  ? 566 HOH B O   1 
HETATM 9248 O O   . HOH I 4 .   ? -29.564 9.15    12.899  1   37.36  ? 567 HOH B O   1 
HETATM 9249 O O   . HOH I 4 .   ? -19.233 15.799  -17.476 1   56.57  ? 568 HOH B O   1 
HETATM 9250 O O   . HOH I 4 .   ? -31.132 -17.841 -18.473 1   17.18  ? 569 HOH B O   1 
HETATM 9251 O O   . HOH I 4 .   ? -6.835  -20.721 -10.144 1   16.54  ? 570 HOH B O   1 
HETATM 9252 O O   . HOH I 4 .   ? -21.645 10.749  -8.484  1   23.69  ? 571 HOH B O   1 
HETATM 9253 O O   . HOH I 4 .   ? -25.777 -26.062 4.092   1   28.59  ? 572 HOH B O   1 
HETATM 9254 O O   . HOH I 4 .   ? -23.443 8.842   -18.238 1   26.05  ? 573 HOH B O   1 
HETATM 9255 O O   . HOH I 4 .   ? -29.851 -20.811 -11.643 1   35.55  ? 574 HOH B O   1 
HETATM 9256 O O   . HOH I 4 .   ? -35.238 -8.56   -1.35   1   22.34  ? 575 HOH B O   1 
HETATM 9257 O O   . HOH I 4 .   ? -9.307  16.293  2.658   1   40.85  ? 576 HOH B O   1 
HETATM 9258 O O   . HOH I 4 .   ? -35.136 1.584   7.564   1   43.09  ? 577 HOH B O   1 
HETATM 9259 O O   . HOH I 4 .   ? -34.805 -3.542  -1.762  1   35.6   ? 578 HOH B O   1 
HETATM 9260 O O   . HOH I 4 .   ? -21.379 3.862   -26.718 1   27.91  ? 579 HOH B O   1 
HETATM 9261 O O   . HOH I 4 .   ? -2.227  12.268  17.527  1   33.3   ? 580 HOH B O   1 
HETATM 9262 O O   . HOH I 4 .   ? -11.538 18.213  14.619  1   18.82  ? 581 HOH B O   1 
HETATM 9263 O O   . HOH I 4 .   ? -22.734 -28.112 -7.186  1   31.3   ? 582 HOH B O   1 
HETATM 9264 O O   . HOH I 4 .   ? -23.346 -19.419 -18.357 1   42     ? 583 HOH B O   1 
HETATM 9265 O O   . HOH I 4 .   ? -26.55  25.667  7.935   1   26.08  ? 584 HOH B O   1 
HETATM 9266 O O   . HOH I 4 .   ? -28.016 22.487  12.737  1   61.25  ? 585 HOH B O   1 
HETATM 9267 O O   . HOH I 4 .   ? -6.228  -6.684  -1.848  1   23.73  ? 586 HOH B O   1 
HETATM 9268 O O   . HOH I 4 .   ? -25.972 8.402   19.86   1   18.49  ? 587 HOH B O   1 
HETATM 9269 O O   . HOH I 4 .   ? -27.564 21.066  7.475   1   29.11  ? 588 HOH B O   1 
HETATM 9270 O O   . HOH I 4 .   ? -23.773 -20.223 -13.13  1   37.73  ? 589 HOH B O   1 
HETATM 9271 O O   . HOH I 4 .   ? -42.711 -3.341  -8.117  1   52.46  ? 590 HOH B O   1 
HETATM 9272 O O   . HOH I 4 .   ? -22.056 -0.158  -26.064 1   25.54  ? 591 HOH B O   1 
HETATM 9273 O O   . HOH I 4 .   ? -28.052 -19.228 5.828   1   36.63  ? 592 HOH B O   1 
HETATM 9274 O O   . HOH I 4 .   ? -28.794 11.466  -10.369 1   23.58  ? 593 HOH B O   1 
HETATM 9275 O O   . HOH I 4 .   ? -38.979 -10.702 -4.658  1   35.48  ? 594 HOH B O   1 
HETATM 9276 O O   . HOH I 4 .   ? -24.135 10.036  -11.201 1   34.84  ? 595 HOH B O   1 
HETATM 9277 O O   . HOH I 4 .   ? -39.974 -18.214 -12.694 1   29.73  ? 596 HOH B O   1 
HETATM 9278 O O   . HOH I 4 .   ? -34.949 -9.745  1.277   1   24.19  ? 597 HOH B O   1 
HETATM 9279 O O   . HOH I 4 .   ? -37.643 -9.719  -1.865  1   29.59  ? 598 HOH B O   1 
HETATM 9280 O O   . HOH I 4 .   ? -36.247 -6.069  -1.793  1   29.35  ? 599 HOH B O   1 
HETATM 9281 O O   . HOH I 4 .   ? -15.629 -11.472 -10.655 1   31.78  ? 600 HOH B O   1 
HETATM 9282 O O   . HOH I 4 .   ? -27.957 -22.266 -13.645 1   40.07  ? 601 HOH B O   1 
HETATM 9283 O O   . HOH I 4 .   ? -36.228 -7.192  2.68    1   29.58  ? 602 HOH B O   1 
HETATM 9284 O O   . HOH J 4 .   ? -37.327 12.303  19.761  1   32.5   ? 401 HOH C O   1 
HETATM 9285 O O   . HOH J 4 .   ? -45.752 -5.371  28.59   1   44.72  ? 402 HOH C O   1 
HETATM 9286 O O   . HOH J 4 .   ? -28.468 15.933  21.109  1   38.41  ? 403 HOH C O   1 
HETATM 9287 O O   . HOH J 4 .   ? -20.341 1.444   43.767  1   39.77  ? 404 HOH C O   1 
HETATM 9288 O O   . HOH J 4 .   ? -38.415 34.338  24.83   1   66.04  ? 405 HOH C O   1 
HETATM 9289 O O   . HOH J 4 .   ? -45.712 -2.39   35.303  1   14.05  ? 406 HOH C O   1 
HETATM 9290 O O   . HOH J 4 .   ? -43.958 24.609  16.827  1   19     ? 407 HOH C O   1 
HETATM 9291 O O   . HOH J 4 .   ? -58.031 7.702   35.488  1   20.31  ? 408 HOH C O   1 
HETATM 9292 O O   . HOH J 4 .   ? -54.442 2.115   38.516  1   24.24  ? 409 HOH C O   1 
HETATM 9293 O O   . HOH J 4 .   ? -43.886 -0.62   34.691  1   23.28  ? 410 HOH C O   1 
HETATM 9294 O O   . HOH J 4 .   ? -39.246 0.347   44.196  1   30.25  ? 411 HOH C O   1 
HETATM 9295 O O   . HOH J 4 .   ? -57.79  7.005   41.604  1   52.7   ? 412 HOH C O   1 
HETATM 9296 O O   . HOH J 4 .   ? -55.072 9.112   26.171  1   30.29  ? 413 HOH C O   1 
HETATM 9297 O O   . HOH J 4 .   ? -22.971 10.9    21.624  1   24.52  ? 414 HOH C O   1 
HETATM 9298 O O   . HOH J 4 .   ? -42.512 1.456   42.667  1   28     ? 415 HOH C O   1 
HETATM 9299 O O   . HOH J 4 .   ? -52.862 13.659  36.778  1   21.48  ? 416 HOH C O   1 
HETATM 9300 O O   . HOH J 4 .   ? -44.19  7.399   43.803  1   38.82  ? 417 HOH C O   1 
HETATM 9301 O O   . HOH J 4 .   ? -27.251 10.199  18.042  1   27.33  ? 418 HOH C O   1 
HETATM 9302 O O   . HOH J 4 .   ? -51.395 24.209  35.511  1   29.05  ? 419 HOH C O   1 
HETATM 9303 O O   . HOH J 4 .   ? -50.382 6.449   19.095  1   34.67  ? 420 HOH C O   1 
HETATM 9304 O O   . HOH J 4 .   ? -54.785 19.308  39.305  1   20.46  ? 421 HOH C O   1 
HETATM 9305 O O   . HOH J 4 .   ? -24.348 0.124   48.316  1   13.69  ? 422 HOH C O   1 
HETATM 9306 O O   . HOH J 4 .   ? -42.505 9.596   34.633  1   21.99  ? 423 HOH C O   1 
HETATM 9307 O O   . HOH J 4 .   ? -48.96  -3.488  34.812  1   54.15  ? 424 HOH C O   1 
HETATM 9308 O O   . HOH J 4 .   ? -35.144 13.52   32.968  1   51.99  ? 425 HOH C O   1 
HETATM 9309 O O   . HOH J 4 .   ? -35.328 0.531   43.879  1   23.4   ? 426 HOH C O   1 
HETATM 9310 O O   . HOH J 4 .   ? -40.561 38.303  28.677  1   25.26  ? 427 HOH C O   1 
HETATM 9311 O O   . HOH J 4 .   ? -48.984 9.218   18.17   1   56.53  ? 428 HOH C O   1 
HETATM 9312 O O   . HOH J 4 .   ? -22.129 -0.2    28.684  1   53.38  ? 429 HOH C O   1 
HETATM 9313 O O   . HOH J 4 .   ? -35.547 12.542  30.457  1   39.59  ? 430 HOH C O   1 
HETATM 9314 O O   . HOH J 4 .   ? -36.625 7.15    23.586  1   31.15  ? 431 HOH C O   1 
HETATM 9315 O O   . HOH J 4 .   ? -27.747 1.256   24.162  1   31.82  ? 432 HOH C O   1 
HETATM 9316 O O   . HOH J 4 .   ? -35.065 5.583   22.701  1   47.76  ? 433 HOH C O   1 
HETATM 9317 O O   . HOH J 4 .   ? -38.477 9.985   16.382  1   32.57  ? 434 HOH C O   1 
HETATM 9318 O O   . HOH J 4 .   ? -62.67  -4.453  41.161  1   55.15  ? 435 HOH C O   1 
HETATM 9319 O O   . HOH J 4 .   ? -54.24  23.429  53.164  1   31.48  ? 436 HOH C O   1 
HETATM 9320 O O   . HOH J 4 .   ? -52.286 16.61   51.88   1   55.15  ? 437 HOH C O   1 
HETATM 9321 O O   . HOH J 4 .   ? -36.822 16.619  34.385  1   50.31  ? 438 HOH C O   1 
HETATM 9322 O O   . HOH J 4 .   ? -55.309 -4.51   41.678  1   36.24  ? 439 HOH C O   1 
HETATM 9323 O O   . HOH J 4 .   ? -35.858 31.386  26.586  1   30.45  ? 440 HOH C O   1 
HETATM 9324 O O   . HOH J 4 .   ? -40.338 3.426   44.076  1   31.1   ? 441 HOH C O   1 
HETATM 9325 O O   . HOH J 4 .   ? -31.431 12.701  18.62   1   36.92  ? 442 HOH C O   1 
HETATM 9326 O O   . HOH J 4 .   ? -33.016 17.77   34.208  1   44.25  ? 443 HOH C O   1 
HETATM 9327 O O   . HOH K 4 .   ? -29.371 -29.57  29.371  1   36.53  ? 501 HOH D O   1 
HETATM 9328 O O   . HOH K 4 .   ? -27.416 -4.408  40.779  1   43.27  ? 502 HOH D O   1 
HETATM 9329 O O   . HOH K 4 .   ? -45.997 -6.173  33.266  1   25.08  ? 503 HOH D O   1 
HETATM 9330 O O   . HOH K 4 .   ? -38.809 -3.262  28.253  1   37.44  ? 504 HOH D O   1 
HETATM 9331 O O   . HOH K 4 .   ? -53.053 -7.421  32.189  1   41.91  ? 505 HOH D O   1 
HETATM 9332 O O   . HOH K 4 .   ? -22.664 -25.624 40.211  1   25.84  ? 506 HOH D O   1 
HETATM 9333 O O   . HOH K 4 .   ? -46.796 -17.212 43.456  1   20.89  ? 507 HOH D O   1 
HETATM 9334 O O   . HOH K 4 .   ? -50.203 -4.96   28.904  1   30.92  ? 508 HOH D O   1 
HETATM 9335 O O   . HOH K 4 .   ? -49.233 -15.937 17.189  1   28.16  ? 509 HOH D O   1 
HETATM 9336 O O   . HOH K 4 .   ? -25.237 -25.11  31.711  1   25.65  ? 510 HOH D O   1 
HETATM 9337 O O   . HOH K 4 .   ? -48.285 -7.516  45.237  1   17.7   ? 511 HOH D O   1 
HETATM 9338 O O   . HOH K 4 .   ? -38.967 -26.644 32.83   1   25.7   ? 512 HOH D O   1 
HETATM 9339 O O   . HOH K 4 .   ? -28.815 -23.127 41.931  1   22.05  ? 513 HOH D O   1 
HETATM 9340 O O   . HOH K 4 .   ? -37.433 -11.429 54.366  1   51.6   ? 514 HOH D O   1 
HETATM 9341 O O   . HOH K 4 .   ? -36.394 -4.016  46.009  1   33.97  ? 515 HOH D O   1 
HETATM 9342 O O   . HOH K 4 .   ? -29.017 -23.21  44.665  1   30.21  ? 516 HOH D O   1 
HETATM 9343 O O   . HOH K 4 .   ? -46.501 -30.456 31.183  1   29.62  ? 517 HOH D O   1 
HETATM 9344 O O   . HOH K 4 .   ? -22.732 -16.361 26.134  1   38.19  ? 518 HOH D O   1 
HETATM 9345 O O   . HOH K 4 .   ? -46.202 -4.553  45.88   1   34.21  ? 519 HOH D O   1 
HETATM 9346 O O   . HOH K 4 .   ? -43.551 -28.368 44.646  1   31.49  ? 520 HOH D O   1 
HETATM 9347 O O   . HOH K 4 .   ? -42.654 -14.121 24.566  1   39.94  ? 521 HOH D O   1 
HETATM 9348 O O   . HOH K 4 .   ? -42.185 -27.223 48.503  1   56.96  ? 522 HOH D O   1 
HETATM 9349 O O   . HOH K 4 .   ? -26.287 -31.211 37.281  1   32.84  ? 523 HOH D O   1 
HETATM 9350 O O   . HOH K 4 .   ? -59.789 -8.678  33.036  1   55.78  ? 524 HOH D O   1 
HETATM 9351 O O   . HOH K 4 .   ? -48.912 -31.78  34.778  1   29.44  ? 525 HOH D O   1 
HETATM 9352 O O   . HOH K 4 .   ? -40.953 -0.963  42.283  1   30.76  ? 526 HOH D O   1 
HETATM 9353 O O   . HOH K 4 .   ? -46.21  -15.538 30.846  1   27.52  ? 527 HOH D O   1 
HETATM 9354 O O   . HOH K 4 .   ? -56.199 1.238   19.901  1   33.76  ? 528 HOH D O   1 
HETATM 9355 O O   . HOH K 4 .   ? -51.085 -24.268 19.175  1   57.04  ? 529 HOH D O   1 
HETATM 9356 O O   . HOH K 4 .   ? -46.316 -26.062 40.428  1   36.89  ? 530 HOH D O   1 
HETATM 9357 O O   . HOH K 4 .   ? -27.52  -30.962 30.132  1   56.39  ? 531 HOH D O   1 
HETATM 9358 O O   . HOH K 4 .   ? -53.98  -32.587 46.631  1   21.64  ? 532 HOH D O   1 
HETATM 9359 O O   . HOH K 4 .   ? -65.157 -34.831 29.079  1   70.6   ? 533 HOH D O   1 
HETATM 9360 O O   . HOH K 4 .   ? -43.217 -33.97  36.839  1   31.04  ? 534 HOH D O   1 
HETATM 9361 O O   . HOH K 4 .   ? -45.177 -20.434 29.885  1   29.22  ? 535 HOH D O   1 
HETATM 9362 O O   . HOH K 4 .   ? -48.702 -27.642 40.661  1   31.72  ? 536 HOH D O   1 
HETATM 9363 O O   . HOH K 4 .   ? -46.2   -28.091 37.876  1   26.43  ? 537 HOH D O   1 
HETATM 9364 O O   . HOH K 4 .   ? -38.548 -31.981 38.749  1   39.52  ? 538 HOH D O   1 
HETATM 9365 O O   . HOH K 4 .   ? -44.424 -5.836  31.081  1   35.26  ? 539 HOH D O   1 
HETATM 9366 O O   . HOH K 4 .   ? -49.129 -30.776 20.935  1   17.66  ? 540 HOH D O   1 
HETATM 9367 O O   . HOH K 4 .   ? -35.012 -32.835 32.681  1   21.57  ? 541 HOH D O   1 
HETATM 9368 O O   . HOH K 4 .   ? -48.203 -4.06   43.346  1   26.77  ? 542 HOH D O   1 
HETATM 9369 O O   . HOH K 4 .   ? -46.929 -19.758 19.115  1   19.86  ? 543 HOH D O   1 
HETATM 9370 O O   . HOH K 4 .   ? -72.192 -24.276 35.299  1   56.06  ? 544 HOH D O   1 
HETATM 9371 O O   . HOH K 4 .   ? -38.229 -32.691 30.765  1   31.03  ? 545 HOH D O   1 
HETATM 9372 O O   . HOH K 4 .   ? -39.301 -32.073 35.119  1   30.72  ? 546 HOH D O   1 
HETATM 9373 O O   . HOH K 4 .   ? -44.726 -17.785 29.251  1   23.17  ? 547 HOH D O   1 
# 
