data_9ESN
# 
_entry.id   9ESN 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ESN         pdb_00009esn 10.2210/pdb9esn/pdb 
WWPDB D_1292137173 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-09 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ESN 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 jane.endicott@newcastle.ac.uk Jane    Endicott A.   'principal investigator/group leader' 0000-0003-4868-0116 
4 martin.noble@newcastle.ac.uk  Martin  Noble    E.M. 'principal investigator/group leader' 0000-0002-3595-9807 
5 mike.waring@newcastle.ac.uk   Michael Waring   J.   'principal investigator/group leader' 0000-0002-9110-8783 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hope, I.'       1 0000-0002-8002-5026 
'Martin, M.P.'   2 0000-0003-4810-3351 
'Waring, M.J.'   3 0000-0002-9110-8783 
'Noble, M.E.M.'  4 0000-0002-3595-9807 
'Endicott, J.A.' 5 0000-0003-4868-0116 
'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hope, I.'       1 0000-0002-8002-5026 
primary 'Martin, M.P.'   2 0000-0003-4810-3351 
primary 'Waring, M.J.'   3 0000-0002-9110-8783 
primary 'Noble, M.E.M.'  4 0000-0002-3595-9807 
primary 'Endicott, J.A.' 5 0000-0003-4868-0116 
primary 'Tatum, N.J.'    6 0000-0003-3878-9265 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cyclin-dependent kinase 2'                   34354.770 2   2.7.11.22 ? ? ? 
2 polymer     man Cyclin-A2                                     30817.473 2   ?         ? ? ? 
3 non-polymer syn '4-bromo-1-(2-hydroxyethyl)pyridin-2(1H)-one' 218.048   5   ?         ? ? ? 
4 water       nat water                                         18.015    310 ?         ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cell division protein kinase 2,p33 protein kinase' 
2 Cyclin-A                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
;GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL
YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV
RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY
KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
A,C ? 
2 'polypeptide(L)' no no  
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
;GVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
GKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVE
SLAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIR
EKYKNSKYHGVSLLNPPETLNVHHHHHH
;
B,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 '4-bromo-1-(2-hydroxyethyl)pyridin-2(1H)-one' UUS 
4 water                                         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   SER n 
1 5   MET n 
1 6   GLU n 
1 7   ASN n 
1 8   PHE n 
1 9   GLN n 
1 10  LYS n 
1 11  VAL n 
1 12  GLU n 
1 13  LYS n 
1 14  ILE n 
1 15  GLY n 
1 16  GLU n 
1 17  GLY n 
1 18  THR n 
1 19  TYR n 
1 20  GLY n 
1 21  VAL n 
1 22  VAL n 
1 23  TYR n 
1 24  LYS n 
1 25  ALA n 
1 26  ARG n 
1 27  ASN n 
1 28  LYS n 
1 29  LEU n 
1 30  THR n 
1 31  GLY n 
1 32  GLU n 
1 33  VAL n 
1 34  VAL n 
1 35  ALA n 
1 36  LEU n 
1 37  LYS n 
1 38  LYS n 
1 39  ILE n 
1 40  ARG n 
1 41  LEU n 
1 42  ASP n 
1 43  THR n 
1 44  GLU n 
1 45  THR n 
1 46  GLU n 
1 47  GLY n 
1 48  VAL n 
1 49  PRO n 
1 50  SER n 
1 51  THR n 
1 52  ALA n 
1 53  ILE n 
1 54  ARG n 
1 55  GLU n 
1 56  ILE n 
1 57  SER n 
1 58  LEU n 
1 59  LEU n 
1 60  LYS n 
1 61  GLU n 
1 62  LEU n 
1 63  ASN n 
1 64  HIS n 
1 65  PRO n 
1 66  ASN n 
1 67  ILE n 
1 68  VAL n 
1 69  LYS n 
1 70  LEU n 
1 71  LEU n 
1 72  ASP n 
1 73  VAL n 
1 74  ILE n 
1 75  HIS n 
1 76  THR n 
1 77  GLU n 
1 78  ASN n 
1 79  LYS n 
1 80  LEU n 
1 81  TYR n 
1 82  LEU n 
1 83  VAL n 
1 84  PHE n 
1 85  GLU n 
1 86  PHE n 
1 87  LEU n 
1 88  HIS n 
1 89  GLN n 
1 90  ASP n 
1 91  LEU n 
1 92  LYS n 
1 93  LYS n 
1 94  PHE n 
1 95  MET n 
1 96  ASP n 
1 97  ALA n 
1 98  SER n 
1 99  ALA n 
1 100 LEU n 
1 101 THR n 
1 102 GLY n 
1 103 ILE n 
1 104 PRO n 
1 105 LEU n 
1 106 PRO n 
1 107 LEU n 
1 108 ILE n 
1 109 LYS n 
1 110 SER n 
1 111 TYR n 
1 112 LEU n 
1 113 PHE n 
1 114 GLN n 
1 115 LEU n 
1 116 LEU n 
1 117 GLN n 
1 118 GLY n 
1 119 LEU n 
1 120 ALA n 
1 121 PHE n 
1 122 CYS n 
1 123 HIS n 
1 124 SER n 
1 125 HIS n 
1 126 ARG n 
1 127 VAL n 
1 128 LEU n 
1 129 HIS n 
1 130 ARG n 
1 131 ASP n 
1 132 LEU n 
1 133 LYS n 
1 134 PRO n 
1 135 GLN n 
1 136 ASN n 
1 137 LEU n 
1 138 LEU n 
1 139 ILE n 
1 140 ASN n 
1 141 THR n 
1 142 GLU n 
1 143 GLY n 
1 144 ALA n 
1 145 ILE n 
1 146 LYS n 
1 147 LEU n 
1 148 ALA n 
1 149 ASP n 
1 150 PHE n 
1 151 GLY n 
1 152 LEU n 
1 153 ALA n 
1 154 ARG n 
1 155 ALA n 
1 156 PHE n 
1 157 GLY n 
1 158 VAL n 
1 159 PRO n 
1 160 VAL n 
1 161 ARG n 
1 162 THR n 
1 163 TYR n 
1 164 TPO n 
1 165 HIS n 
1 166 GLU n 
1 167 VAL n 
1 168 VAL n 
1 169 THR n 
1 170 LEU n 
1 171 TRP n 
1 172 TYR n 
1 173 ARG n 
1 174 ALA n 
1 175 PRO n 
1 176 GLU n 
1 177 ILE n 
1 178 LEU n 
1 179 LEU n 
1 180 GLY n 
1 181 CYS n 
1 182 LYS n 
1 183 TYR n 
1 184 TYR n 
1 185 SER n 
1 186 THR n 
1 187 ALA n 
1 188 VAL n 
1 189 ASP n 
1 190 ILE n 
1 191 TRP n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 CYS n 
1 196 ILE n 
1 197 PHE n 
1 198 ALA n 
1 199 GLU n 
1 200 MET n 
1 201 VAL n 
1 202 THR n 
1 203 ARG n 
1 204 ARG n 
1 205 ALA n 
1 206 LEU n 
1 207 PHE n 
1 208 PRO n 
1 209 GLY n 
1 210 ASP n 
1 211 SER n 
1 212 GLU n 
1 213 ILE n 
1 214 ASP n 
1 215 GLN n 
1 216 LEU n 
1 217 PHE n 
1 218 ARG n 
1 219 ILE n 
1 220 PHE n 
1 221 ARG n 
1 222 THR n 
1 223 LEU n 
1 224 GLY n 
1 225 THR n 
1 226 PRO n 
1 227 ASP n 
1 228 GLU n 
1 229 VAL n 
1 230 VAL n 
1 231 TRP n 
1 232 PRO n 
1 233 GLY n 
1 234 VAL n 
1 235 THR n 
1 236 SER n 
1 237 MET n 
1 238 PRO n 
1 239 ASP n 
1 240 TYR n 
1 241 LYS n 
1 242 PRO n 
1 243 SER n 
1 244 PHE n 
1 245 PRO n 
1 246 LYS n 
1 247 TRP n 
1 248 ALA n 
1 249 ARG n 
1 250 GLN n 
1 251 ASP n 
1 252 PHE n 
1 253 SER n 
1 254 LYS n 
1 255 VAL n 
1 256 VAL n 
1 257 PRO n 
1 258 PRO n 
1 259 LEU n 
1 260 ASP n 
1 261 GLU n 
1 262 ASP n 
1 263 GLY n 
1 264 ARG n 
1 265 SER n 
1 266 LEU n 
1 267 LEU n 
1 268 SER n 
1 269 GLN n 
1 270 MET n 
1 271 LEU n 
1 272 HIS n 
1 273 TYR n 
1 274 ASP n 
1 275 PRO n 
1 276 ASN n 
1 277 LYS n 
1 278 ARG n 
1 279 ILE n 
1 280 SER n 
1 281 ALA n 
1 282 LYS n 
1 283 ALA n 
1 284 ALA n 
1 285 LEU n 
1 286 ALA n 
1 287 HIS n 
1 288 PRO n 
1 289 PHE n 
1 290 PHE n 
1 291 GLN n 
1 292 ASP n 
1 293 VAL n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 VAL n 
1 298 PRO n 
1 299 HIS n 
1 300 LEU n 
1 301 ARG n 
1 302 LEU n 
2 1   GLY n 
2 2   VAL n 
2 3   ASN n 
2 4   GLU n 
2 5   VAL n 
2 6   PRO n 
2 7   ASP n 
2 8   TYR n 
2 9   HIS n 
2 10  GLU n 
2 11  ASP n 
2 12  ILE n 
2 13  HIS n 
2 14  THR n 
2 15  TYR n 
2 16  LEU n 
2 17  ARG n 
2 18  GLU n 
2 19  MET n 
2 20  GLU n 
2 21  VAL n 
2 22  LYS n 
2 23  CYS n 
2 24  LYS n 
2 25  PRO n 
2 26  LYS n 
2 27  VAL n 
2 28  GLY n 
2 29  TYR n 
2 30  MET n 
2 31  LYS n 
2 32  LYS n 
2 33  GLN n 
2 34  PRO n 
2 35  ASP n 
2 36  ILE n 
2 37  THR n 
2 38  ASN n 
2 39  SER n 
2 40  MET n 
2 41  ARG n 
2 42  ALA n 
2 43  ILE n 
2 44  LEU n 
2 45  VAL n 
2 46  ASP n 
2 47  TRP n 
2 48  LEU n 
2 49  VAL n 
2 50  GLU n 
2 51  VAL n 
2 52  GLY n 
2 53  GLU n 
2 54  GLU n 
2 55  TYR n 
2 56  LYS n 
2 57  LEU n 
2 58  GLN n 
2 59  ASN n 
2 60  GLU n 
2 61  THR n 
2 62  LEU n 
2 63  HIS n 
2 64  LEU n 
2 65  ALA n 
2 66  VAL n 
2 67  ASN n 
2 68  TYR n 
2 69  ILE n 
2 70  ASP n 
2 71  ARG n 
2 72  PHE n 
2 73  LEU n 
2 74  SER n 
2 75  SER n 
2 76  MET n 
2 77  SER n 
2 78  VAL n 
2 79  LEU n 
2 80  ARG n 
2 81  GLY n 
2 82  LYS n 
2 83  LEU n 
2 84  GLN n 
2 85  LEU n 
2 86  VAL n 
2 87  GLY n 
2 88  THR n 
2 89  ALA n 
2 90  ALA n 
2 91  MET n 
2 92  LEU n 
2 93  LEU n 
2 94  ALA n 
2 95  SER n 
2 96  LYS n 
2 97  PHE n 
2 98  GLU n 
2 99  GLU n 
2 100 ILE n 
2 101 TYR n 
2 102 PRO n 
2 103 PRO n 
2 104 GLU n 
2 105 VAL n 
2 106 ALA n 
2 107 GLU n 
2 108 PHE n 
2 109 VAL n 
2 110 TYR n 
2 111 ILE n 
2 112 THR n 
2 113 ASP n 
2 114 ASP n 
2 115 THR n 
2 116 TYR n 
2 117 THR n 
2 118 LYS n 
2 119 LYS n 
2 120 GLN n 
2 121 VAL n 
2 122 LEU n 
2 123 ARG n 
2 124 MET n 
2 125 GLU n 
2 126 HIS n 
2 127 LEU n 
2 128 VAL n 
2 129 LEU n 
2 130 LYS n 
2 131 VAL n 
2 132 LEU n 
2 133 ALA n 
2 134 PHE n 
2 135 ASP n 
2 136 LEU n 
2 137 ALA n 
2 138 ALA n 
2 139 PRO n 
2 140 THR n 
2 141 ILE n 
2 142 ASN n 
2 143 GLN n 
2 144 PHE n 
2 145 LEU n 
2 146 THR n 
2 147 GLN n 
2 148 TYR n 
2 149 PHE n 
2 150 LEU n 
2 151 HIS n 
2 152 GLN n 
2 153 GLN n 
2 154 PRO n 
2 155 ALA n 
2 156 ASN n 
2 157 CYS n 
2 158 LYS n 
2 159 VAL n 
2 160 GLU n 
2 161 SER n 
2 162 LEU n 
2 163 ALA n 
2 164 MET n 
2 165 PHE n 
2 166 LEU n 
2 167 GLY n 
2 168 GLU n 
2 169 LEU n 
2 170 SER n 
2 171 LEU n 
2 172 ILE n 
2 173 ASP n 
2 174 ALA n 
2 175 ASP n 
2 176 PRO n 
2 177 TYR n 
2 178 LEU n 
2 179 LYS n 
2 180 TYR n 
2 181 LEU n 
2 182 PRO n 
2 183 SER n 
2 184 VAL n 
2 185 ILE n 
2 186 ALA n 
2 187 ALA n 
2 188 ALA n 
2 189 ALA n 
2 190 PHE n 
2 191 HIS n 
2 192 LEU n 
2 193 ALA n 
2 194 LEU n 
2 195 TYR n 
2 196 THR n 
2 197 VAL n 
2 198 THR n 
2 199 GLY n 
2 200 GLN n 
2 201 SER n 
2 202 TRP n 
2 203 PRO n 
2 204 GLU n 
2 205 SER n 
2 206 LEU n 
2 207 VAL n 
2 208 GLN n 
2 209 LYS n 
2 210 THR n 
2 211 GLY n 
2 212 TYR n 
2 213 THR n 
2 214 LEU n 
2 215 GLU n 
2 216 THR n 
2 217 LEU n 
2 218 LYS n 
2 219 PRO n 
2 220 CYS n 
2 221 LEU n 
2 222 LEU n 
2 223 ASP n 
2 224 LEU n 
2 225 HIS n 
2 226 GLN n 
2 227 THR n 
2 228 TYR n 
2 229 LEU n 
2 230 ARG n 
2 231 ALA n 
2 232 PRO n 
2 233 GLN n 
2 234 HIS n 
2 235 ALA n 
2 236 GLN n 
2 237 GLN n 
2 238 SER n 
2 239 ILE n 
2 240 ARG n 
2 241 GLU n 
2 242 LYS n 
2 243 TYR n 
2 244 LYS n 
2 245 ASN n 
2 246 SER n 
2 247 LYS n 
2 248 TYR n 
2 249 HIS n 
2 250 GLY n 
2 251 VAL n 
2 252 SER n 
2 253 LEU n 
2 254 LEU n 
2 255 ASN n 
2 256 PRO n 
2 257 PRO n 
2 258 GLU n 
2 259 THR n 
2 260 LEU n 
2 261 ASN n 
2 262 VAL n 
2 263 HIS n 
2 264 HIS n 
2 265 HIS n 
2 266 HIS n 
2 267 HIS n 
2 268 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 302 human  ? 'CDK2, CDKN2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PGEX6P1 ? ? 
2 1 sample 'Biological sequence' 1 268 cattle ? CCNA2         ? ? ? ? ? ? 'Bos taurus'   9913 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? PET21d  ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                       ?                  'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                      ?                  'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                    ?                  'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                               ?                  'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                      ?                  'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                     ?                  'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                               ?                  'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                       ?                  'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                     ?                  'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                         ?                  'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                    ?                  'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                       ?                  'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                        ?                  'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                    ?                  'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                 ?                  'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                       ?                  'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                        ?                  'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                     ?                  'C4 H9 N O3'     119.119 
TPO 'L-peptide linking' n PHOSPHOTHREONINE                              PHOSPHONOTHREONINE 'C4 H10 N O6 P'  199.099 
TRP 'L-peptide linking' y TRYPTOPHAN                                    ?                  'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                      ?                  'C9 H11 N O3'    181.189 
UUS non-polymer         . '4-bromo-1-(2-hydroxyethyl)pyridin-2(1H)-one' ?                  'C7 H8 Br N O2'  218.048 
VAL 'L-peptide linking' y VALINE                                        ?                  'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -3  -3  GLY GLY A . n 
A 1 2   PRO 2   -2  -2  PRO PRO A . n 
A 1 3   GLY 3   -1  -1  GLY GLY A . n 
A 1 4   SER 4   0   0   SER SER A . n 
A 1 5   MET 5   1   1   MET MET A . n 
A 1 6   GLU 6   2   2   GLU GLU A . n 
A 1 7   ASN 7   3   3   ASN ASN A . n 
A 1 8   PHE 8   4   4   PHE PHE A . n 
A 1 9   GLN 9   5   5   GLN GLN A . n 
A 1 10  LYS 10  6   6   LYS LYS A . n 
A 1 11  VAL 11  7   7   VAL VAL A . n 
A 1 12  GLU 12  8   8   GLU GLU A . n 
A 1 13  LYS 13  9   9   LYS LYS A . n 
A 1 14  ILE 14  10  10  ILE ILE A . n 
A 1 15  GLY 15  11  11  GLY GLY A . n 
A 1 16  GLU 16  12  12  GLU GLU A . n 
A 1 17  GLY 17  13  13  GLY GLY A . n 
A 1 18  THR 18  14  14  THR THR A . n 
A 1 19  TYR 19  15  15  TYR TYR A . n 
A 1 20  GLY 20  16  16  GLY GLY A . n 
A 1 21  VAL 21  17  17  VAL VAL A . n 
A 1 22  VAL 22  18  18  VAL VAL A . n 
A 1 23  TYR 23  19  19  TYR TYR A . n 
A 1 24  LYS 24  20  20  LYS LYS A . n 
A 1 25  ALA 25  21  21  ALA ALA A . n 
A 1 26  ARG 26  22  22  ARG ARG A . n 
A 1 27  ASN 27  23  23  ASN ASN A . n 
A 1 28  LYS 28  24  24  LYS LYS A . n 
A 1 29  LEU 29  25  25  LEU LEU A . n 
A 1 30  THR 30  26  26  THR THR A . n 
A 1 31  GLY 31  27  27  GLY GLY A . n 
A 1 32  GLU 32  28  28  GLU GLU A . n 
A 1 33  VAL 33  29  29  VAL VAL A . n 
A 1 34  VAL 34  30  30  VAL VAL A . n 
A 1 35  ALA 35  31  31  ALA ALA A . n 
A 1 36  LEU 36  32  32  LEU LEU A . n 
A 1 37  LYS 37  33  33  LYS LYS A . n 
A 1 38  LYS 38  34  34  LYS LYS A . n 
A 1 39  ILE 39  35  35  ILE ILE A . n 
A 1 40  ARG 40  36  36  ARG ARG A . n 
A 1 41  LEU 41  37  37  LEU LEU A . n 
A 1 42  ASP 42  38  38  ASP ASP A . n 
A 1 43  THR 43  39  39  THR THR A . n 
A 1 44  GLU 44  40  40  GLU GLU A . n 
A 1 45  THR 45  41  41  THR THR A . n 
A 1 46  GLU 46  42  42  GLU GLU A . n 
A 1 47  GLY 47  43  43  GLY GLY A . n 
A 1 48  VAL 48  44  44  VAL VAL A . n 
A 1 49  PRO 49  45  45  PRO PRO A . n 
A 1 50  SER 50  46  46  SER SER A . n 
A 1 51  THR 51  47  47  THR THR A . n 
A 1 52  ALA 52  48  48  ALA ALA A . n 
A 1 53  ILE 53  49  49  ILE ILE A . n 
A 1 54  ARG 54  50  50  ARG ARG A . n 
A 1 55  GLU 55  51  51  GLU GLU A . n 
A 1 56  ILE 56  52  52  ILE ILE A . n 
A 1 57  SER 57  53  53  SER SER A . n 
A 1 58  LEU 58  54  54  LEU LEU A . n 
A 1 59  LEU 59  55  55  LEU LEU A . n 
A 1 60  LYS 60  56  56  LYS LYS A . n 
A 1 61  GLU 61  57  57  GLU GLU A . n 
A 1 62  LEU 62  58  58  LEU LEU A . n 
A 1 63  ASN 63  59  59  ASN ASN A . n 
A 1 64  HIS 64  60  60  HIS HIS A . n 
A 1 65  PRO 65  61  61  PRO PRO A . n 
A 1 66  ASN 66  62  62  ASN ASN A . n 
A 1 67  ILE 67  63  63  ILE ILE A . n 
A 1 68  VAL 68  64  64  VAL VAL A . n 
A 1 69  LYS 69  65  65  LYS LYS A . n 
A 1 70  LEU 70  66  66  LEU LEU A . n 
A 1 71  LEU 71  67  67  LEU LEU A . n 
A 1 72  ASP 72  68  68  ASP ASP A . n 
A 1 73  VAL 73  69  69  VAL VAL A . n 
A 1 74  ILE 74  70  70  ILE ILE A . n 
A 1 75  HIS 75  71  71  HIS HIS A . n 
A 1 76  THR 76  72  72  THR THR A . n 
A 1 77  GLU 77  73  73  GLU GLU A . n 
A 1 78  ASN 78  74  74  ASN ASN A . n 
A 1 79  LYS 79  75  75  LYS LYS A . n 
A 1 80  LEU 80  76  76  LEU LEU A . n 
A 1 81  TYR 81  77  77  TYR TYR A . n 
A 1 82  LEU 82  78  78  LEU LEU A . n 
A 1 83  VAL 83  79  79  VAL VAL A . n 
A 1 84  PHE 84  80  80  PHE PHE A . n 
A 1 85  GLU 85  81  81  GLU GLU A . n 
A 1 86  PHE 86  82  82  PHE PHE A . n 
A 1 87  LEU 87  83  83  LEU LEU A . n 
A 1 88  HIS 88  84  84  HIS HIS A . n 
A 1 89  GLN 89  85  85  GLN GLN A . n 
A 1 90  ASP 90  86  86  ASP ASP A . n 
A 1 91  LEU 91  87  87  LEU LEU A . n 
A 1 92  LYS 92  88  88  LYS LYS A . n 
A 1 93  LYS 93  89  89  LYS LYS A . n 
A 1 94  PHE 94  90  90  PHE PHE A . n 
A 1 95  MET 95  91  91  MET MET A . n 
A 1 96  ASP 96  92  92  ASP ASP A . n 
A 1 97  ALA 97  93  93  ALA ALA A . n 
A 1 98  SER 98  94  94  SER SER A . n 
A 1 99  ALA 99  95  95  ALA ALA A . n 
A 1 100 LEU 100 96  96  LEU LEU A . n 
A 1 101 THR 101 97  97  THR THR A . n 
A 1 102 GLY 102 98  98  GLY GLY A . n 
A 1 103 ILE 103 99  99  ILE ILE A . n 
A 1 104 PRO 104 100 100 PRO PRO A . n 
A 1 105 LEU 105 101 101 LEU LEU A . n 
A 1 106 PRO 106 102 102 PRO PRO A . n 
A 1 107 LEU 107 103 103 LEU LEU A . n 
A 1 108 ILE 108 104 104 ILE ILE A . n 
A 1 109 LYS 109 105 105 LYS LYS A . n 
A 1 110 SER 110 106 106 SER SER A . n 
A 1 111 TYR 111 107 107 TYR TYR A . n 
A 1 112 LEU 112 108 108 LEU LEU A . n 
A 1 113 PHE 113 109 109 PHE PHE A . n 
A 1 114 GLN 114 110 110 GLN GLN A . n 
A 1 115 LEU 115 111 111 LEU LEU A . n 
A 1 116 LEU 116 112 112 LEU LEU A . n 
A 1 117 GLN 117 113 113 GLN GLN A . n 
A 1 118 GLY 118 114 114 GLY GLY A . n 
A 1 119 LEU 119 115 115 LEU LEU A . n 
A 1 120 ALA 120 116 116 ALA ALA A . n 
A 1 121 PHE 121 117 117 PHE PHE A . n 
A 1 122 CYS 122 118 118 CYS CYS A . n 
A 1 123 HIS 123 119 119 HIS HIS A . n 
A 1 124 SER 124 120 120 SER SER A . n 
A 1 125 HIS 125 121 121 HIS HIS A . n 
A 1 126 ARG 126 122 122 ARG ARG A . n 
A 1 127 VAL 127 123 123 VAL VAL A . n 
A 1 128 LEU 128 124 124 LEU LEU A . n 
A 1 129 HIS 129 125 125 HIS HIS A . n 
A 1 130 ARG 130 126 126 ARG ARG A . n 
A 1 131 ASP 131 127 127 ASP ASP A . n 
A 1 132 LEU 132 128 128 LEU LEU A . n 
A 1 133 LYS 133 129 129 LYS LYS A . n 
A 1 134 PRO 134 130 130 PRO PRO A . n 
A 1 135 GLN 135 131 131 GLN GLN A . n 
A 1 136 ASN 136 132 132 ASN ASN A . n 
A 1 137 LEU 137 133 133 LEU LEU A . n 
A 1 138 LEU 138 134 134 LEU LEU A . n 
A 1 139 ILE 139 135 135 ILE ILE A . n 
A 1 140 ASN 140 136 136 ASN ASN A . n 
A 1 141 THR 141 137 137 THR THR A . n 
A 1 142 GLU 142 138 138 GLU GLU A . n 
A 1 143 GLY 143 139 139 GLY GLY A . n 
A 1 144 ALA 144 140 140 ALA ALA A . n 
A 1 145 ILE 145 141 141 ILE ILE A . n 
A 1 146 LYS 146 142 142 LYS LYS A . n 
A 1 147 LEU 147 143 143 LEU LEU A . n 
A 1 148 ALA 148 144 144 ALA ALA A . n 
A 1 149 ASP 149 145 145 ASP ASP A . n 
A 1 150 PHE 150 146 146 PHE PHE A . n 
A 1 151 GLY 151 147 147 GLY GLY A . n 
A 1 152 LEU 152 148 148 LEU LEU A . n 
A 1 153 ALA 153 149 149 ALA ALA A . n 
A 1 154 ARG 154 150 150 ARG ARG A . n 
A 1 155 ALA 155 151 151 ALA ALA A . n 
A 1 156 PHE 156 152 152 PHE PHE A . n 
A 1 157 GLY 157 153 153 GLY GLY A . n 
A 1 158 VAL 158 154 154 VAL VAL A . n 
A 1 159 PRO 159 155 155 PRO PRO A . n 
A 1 160 VAL 160 156 156 VAL VAL A . n 
A 1 161 ARG 161 157 157 ARG ARG A . n 
A 1 162 THR 162 158 158 THR THR A . n 
A 1 163 TYR 163 159 159 TYR TYR A . n 
A 1 164 TPO 164 160 160 TPO TPO A . n 
A 1 165 HIS 165 161 161 HIS HIS A . n 
A 1 166 GLU 166 162 162 GLU GLU A . n 
A 1 167 VAL 167 163 163 VAL VAL A . n 
A 1 168 VAL 168 164 164 VAL VAL A . n 
A 1 169 THR 169 165 165 THR THR A . n 
A 1 170 LEU 170 166 166 LEU LEU A . n 
A 1 171 TRP 171 167 167 TRP TRP A . n 
A 1 172 TYR 172 168 168 TYR TYR A . n 
A 1 173 ARG 173 169 169 ARG ARG A . n 
A 1 174 ALA 174 170 170 ALA ALA A . n 
A 1 175 PRO 175 171 171 PRO PRO A . n 
A 1 176 GLU 176 172 172 GLU GLU A . n 
A 1 177 ILE 177 173 173 ILE ILE A . n 
A 1 178 LEU 178 174 174 LEU LEU A . n 
A 1 179 LEU 179 175 175 LEU LEU A . n 
A 1 180 GLY 180 176 176 GLY GLY A . n 
A 1 181 CYS 181 177 177 CYS CYS A . n 
A 1 182 LYS 182 178 178 LYS LYS A . n 
A 1 183 TYR 183 179 179 TYR TYR A . n 
A 1 184 TYR 184 180 180 TYR TYR A . n 
A 1 185 SER 185 181 181 SER SER A . n 
A 1 186 THR 186 182 182 THR THR A . n 
A 1 187 ALA 187 183 183 ALA ALA A . n 
A 1 188 VAL 188 184 184 VAL VAL A . n 
A 1 189 ASP 189 185 185 ASP ASP A . n 
A 1 190 ILE 190 186 186 ILE ILE A . n 
A 1 191 TRP 191 187 187 TRP TRP A . n 
A 1 192 SER 192 188 188 SER SER A . n 
A 1 193 LEU 193 189 189 LEU LEU A . n 
A 1 194 GLY 194 190 190 GLY GLY A . n 
A 1 195 CYS 195 191 191 CYS CYS A . n 
A 1 196 ILE 196 192 192 ILE ILE A . n 
A 1 197 PHE 197 193 193 PHE PHE A . n 
A 1 198 ALA 198 194 194 ALA ALA A . n 
A 1 199 GLU 199 195 195 GLU GLU A . n 
A 1 200 MET 200 196 196 MET MET A . n 
A 1 201 VAL 201 197 197 VAL VAL A . n 
A 1 202 THR 202 198 198 THR THR A . n 
A 1 203 ARG 203 199 199 ARG ARG A . n 
A 1 204 ARG 204 200 200 ARG ARG A . n 
A 1 205 ALA 205 201 201 ALA ALA A . n 
A 1 206 LEU 206 202 202 LEU LEU A . n 
A 1 207 PHE 207 203 203 PHE PHE A . n 
A 1 208 PRO 208 204 204 PRO PRO A . n 
A 1 209 GLY 209 205 205 GLY GLY A . n 
A 1 210 ASP 210 206 206 ASP ASP A . n 
A 1 211 SER 211 207 207 SER SER A . n 
A 1 212 GLU 212 208 208 GLU GLU A . n 
A 1 213 ILE 213 209 209 ILE ILE A . n 
A 1 214 ASP 214 210 210 ASP ASP A . n 
A 1 215 GLN 215 211 211 GLN GLN A . n 
A 1 216 LEU 216 212 212 LEU LEU A . n 
A 1 217 PHE 217 213 213 PHE PHE A . n 
A 1 218 ARG 218 214 214 ARG ARG A . n 
A 1 219 ILE 219 215 215 ILE ILE A . n 
A 1 220 PHE 220 216 216 PHE PHE A . n 
A 1 221 ARG 221 217 217 ARG ARG A . n 
A 1 222 THR 222 218 218 THR THR A . n 
A 1 223 LEU 223 219 219 LEU LEU A . n 
A 1 224 GLY 224 220 220 GLY GLY A . n 
A 1 225 THR 225 221 221 THR THR A . n 
A 1 226 PRO 226 222 222 PRO PRO A . n 
A 1 227 ASP 227 223 223 ASP ASP A . n 
A 1 228 GLU 228 224 224 GLU GLU A . n 
A 1 229 VAL 229 225 225 VAL VAL A . n 
A 1 230 VAL 230 226 226 VAL VAL A . n 
A 1 231 TRP 231 227 227 TRP TRP A . n 
A 1 232 PRO 232 228 228 PRO PRO A . n 
A 1 233 GLY 233 229 229 GLY GLY A . n 
A 1 234 VAL 234 230 230 VAL VAL A . n 
A 1 235 THR 235 231 231 THR THR A . n 
A 1 236 SER 236 232 232 SER SER A . n 
A 1 237 MET 237 233 233 MET MET A . n 
A 1 238 PRO 238 234 234 PRO PRO A . n 
A 1 239 ASP 239 235 235 ASP ASP A . n 
A 1 240 TYR 240 236 236 TYR TYR A . n 
A 1 241 LYS 241 237 237 LYS LYS A . n 
A 1 242 PRO 242 238 238 PRO PRO A . n 
A 1 243 SER 243 239 239 SER SER A . n 
A 1 244 PHE 244 240 240 PHE PHE A . n 
A 1 245 PRO 245 241 241 PRO PRO A . n 
A 1 246 LYS 246 242 242 LYS LYS A . n 
A 1 247 TRP 247 243 243 TRP TRP A . n 
A 1 248 ALA 248 244 244 ALA ALA A . n 
A 1 249 ARG 249 245 245 ARG ARG A . n 
A 1 250 GLN 250 246 246 GLN GLN A . n 
A 1 251 ASP 251 247 247 ASP ASP A . n 
A 1 252 PHE 252 248 248 PHE PHE A . n 
A 1 253 SER 253 249 249 SER SER A . n 
A 1 254 LYS 254 250 250 LYS LYS A . n 
A 1 255 VAL 255 251 251 VAL VAL A . n 
A 1 256 VAL 256 252 252 VAL VAL A . n 
A 1 257 PRO 257 253 253 PRO PRO A . n 
A 1 258 PRO 258 254 254 PRO PRO A . n 
A 1 259 LEU 259 255 255 LEU LEU A . n 
A 1 260 ASP 260 256 256 ASP ASP A . n 
A 1 261 GLU 261 257 257 GLU GLU A . n 
A 1 262 ASP 262 258 258 ASP ASP A . n 
A 1 263 GLY 263 259 259 GLY GLY A . n 
A 1 264 ARG 264 260 260 ARG ARG A . n 
A 1 265 SER 265 261 261 SER SER A . n 
A 1 266 LEU 266 262 262 LEU LEU A . n 
A 1 267 LEU 267 263 263 LEU LEU A . n 
A 1 268 SER 268 264 264 SER SER A . n 
A 1 269 GLN 269 265 265 GLN GLN A . n 
A 1 270 MET 270 266 266 MET MET A . n 
A 1 271 LEU 271 267 267 LEU LEU A . n 
A 1 272 HIS 272 268 268 HIS HIS A . n 
A 1 273 TYR 273 269 269 TYR TYR A . n 
A 1 274 ASP 274 270 270 ASP ASP A . n 
A 1 275 PRO 275 271 271 PRO PRO A . n 
A 1 276 ASN 276 272 272 ASN ASN A . n 
A 1 277 LYS 277 273 273 LYS LYS A . n 
A 1 278 ARG 278 274 274 ARG ARG A . n 
A 1 279 ILE 279 275 275 ILE ILE A . n 
A 1 280 SER 280 276 276 SER SER A . n 
A 1 281 ALA 281 277 277 ALA ALA A . n 
A 1 282 LYS 282 278 278 LYS LYS A . n 
A 1 283 ALA 283 279 279 ALA ALA A . n 
A 1 284 ALA 284 280 280 ALA ALA A . n 
A 1 285 LEU 285 281 281 LEU LEU A . n 
A 1 286 ALA 286 282 282 ALA ALA A . n 
A 1 287 HIS 287 283 283 HIS HIS A . n 
A 1 288 PRO 288 284 284 PRO PRO A . n 
A 1 289 PHE 289 285 285 PHE PHE A . n 
A 1 290 PHE 290 286 286 PHE PHE A . n 
A 1 291 GLN 291 287 287 GLN GLN A . n 
A 1 292 ASP 292 288 288 ASP ASP A . n 
A 1 293 VAL 293 289 289 VAL VAL A . n 
A 1 294 THR 294 290 290 THR THR A . n 
A 1 295 LYS 295 291 291 LYS LYS A . n 
A 1 296 PRO 296 292 292 PRO PRO A . n 
A 1 297 VAL 297 293 293 VAL VAL A . n 
A 1 298 PRO 298 294 294 PRO PRO A . n 
A 1 299 HIS 299 295 ?   ?   ?   A . n 
A 1 300 LEU 300 296 ?   ?   ?   A . n 
A 1 301 ARG 301 297 ?   ?   ?   A . n 
A 1 302 LEU 302 298 ?   ?   ?   A . n 
B 2 1   GLY 1   171 171 GLY GLY B . n 
B 2 2   VAL 2   172 172 VAL VAL B . n 
B 2 3   ASN 3   173 173 ASN ASN B . n 
B 2 4   GLU 4   174 174 GLU GLU B . n 
B 2 5   VAL 5   175 175 VAL VAL B . n 
B 2 6   PRO 6   176 176 PRO PRO B . n 
B 2 7   ASP 7   177 177 ASP ASP B . n 
B 2 8   TYR 8   178 178 TYR TYR B . n 
B 2 9   HIS 9   179 179 HIS HIS B . n 
B 2 10  GLU 10  180 180 GLU GLU B . n 
B 2 11  ASP 11  181 181 ASP ASP B . n 
B 2 12  ILE 12  182 182 ILE ILE B . n 
B 2 13  HIS 13  183 183 HIS HIS B . n 
B 2 14  THR 14  184 184 THR THR B . n 
B 2 15  TYR 15  185 185 TYR TYR B . n 
B 2 16  LEU 16  186 186 LEU LEU B . n 
B 2 17  ARG 17  187 187 ARG ARG B . n 
B 2 18  GLU 18  188 188 GLU GLU B . n 
B 2 19  MET 19  189 189 MET MET B . n 
B 2 20  GLU 20  190 190 GLU GLU B . n 
B 2 21  VAL 21  191 191 VAL VAL B . n 
B 2 22  LYS 22  192 192 LYS LYS B . n 
B 2 23  CYS 23  193 193 CYS CYS B . n 
B 2 24  LYS 24  194 194 LYS LYS B . n 
B 2 25  PRO 25  195 195 PRO PRO B . n 
B 2 26  LYS 26  196 196 LYS LYS B . n 
B 2 27  VAL 27  197 197 VAL VAL B . n 
B 2 28  GLY 28  198 198 GLY GLY B . n 
B 2 29  TYR 29  199 199 TYR TYR B . n 
B 2 30  MET 30  200 200 MET MET B . n 
B 2 31  LYS 31  201 201 LYS LYS B . n 
B 2 32  LYS 32  202 202 LYS LYS B . n 
B 2 33  GLN 33  203 203 GLN GLN B . n 
B 2 34  PRO 34  204 204 PRO PRO B . n 
B 2 35  ASP 35  205 205 ASP ASP B . n 
B 2 36  ILE 36  206 206 ILE ILE B . n 
B 2 37  THR 37  207 207 THR THR B . n 
B 2 38  ASN 38  208 208 ASN ASN B . n 
B 2 39  SER 39  209 209 SER SER B . n 
B 2 40  MET 40  210 210 MET MET B . n 
B 2 41  ARG 41  211 211 ARG ARG B . n 
B 2 42  ALA 42  212 212 ALA ALA B . n 
B 2 43  ILE 43  213 213 ILE ILE B . n 
B 2 44  LEU 44  214 214 LEU LEU B . n 
B 2 45  VAL 45  215 215 VAL VAL B . n 
B 2 46  ASP 46  216 216 ASP ASP B . n 
B 2 47  TRP 47  217 217 TRP TRP B . n 
B 2 48  LEU 48  218 218 LEU LEU B . n 
B 2 49  VAL 49  219 219 VAL VAL B . n 
B 2 50  GLU 50  220 220 GLU GLU B . n 
B 2 51  VAL 51  221 221 VAL VAL B . n 
B 2 52  GLY 52  222 222 GLY GLY B . n 
B 2 53  GLU 53  223 223 GLU GLU B . n 
B 2 54  GLU 54  224 224 GLU GLU B . n 
B 2 55  TYR 55  225 225 TYR TYR B . n 
B 2 56  LYS 56  226 226 LYS LYS B . n 
B 2 57  LEU 57  227 227 LEU LEU B . n 
B 2 58  GLN 58  228 228 GLN GLN B . n 
B 2 59  ASN 59  229 229 ASN ASN B . n 
B 2 60  GLU 60  230 230 GLU GLU B . n 
B 2 61  THR 61  231 231 THR THR B . n 
B 2 62  LEU 62  232 232 LEU LEU B . n 
B 2 63  HIS 63  233 233 HIS HIS B . n 
B 2 64  LEU 64  234 234 LEU LEU B . n 
B 2 65  ALA 65  235 235 ALA ALA B . n 
B 2 66  VAL 66  236 236 VAL VAL B . n 
B 2 67  ASN 67  237 237 ASN ASN B . n 
B 2 68  TYR 68  238 238 TYR TYR B . n 
B 2 69  ILE 69  239 239 ILE ILE B . n 
B 2 70  ASP 70  240 240 ASP ASP B . n 
B 2 71  ARG 71  241 241 ARG ARG B . n 
B 2 72  PHE 72  242 242 PHE PHE B . n 
B 2 73  LEU 73  243 243 LEU LEU B . n 
B 2 74  SER 74  244 244 SER SER B . n 
B 2 75  SER 75  245 245 SER SER B . n 
B 2 76  MET 76  246 246 MET MET B . n 
B 2 77  SER 77  247 247 SER SER B . n 
B 2 78  VAL 78  248 248 VAL VAL B . n 
B 2 79  LEU 79  249 249 LEU LEU B . n 
B 2 80  ARG 80  250 250 ARG ARG B . n 
B 2 81  GLY 81  251 251 GLY GLY B . n 
B 2 82  LYS 82  252 252 LYS LYS B . n 
B 2 83  LEU 83  253 253 LEU LEU B . n 
B 2 84  GLN 84  254 254 GLN GLN B . n 
B 2 85  LEU 85  255 255 LEU LEU B . n 
B 2 86  VAL 86  256 256 VAL VAL B . n 
B 2 87  GLY 87  257 257 GLY GLY B . n 
B 2 88  THR 88  258 258 THR THR B . n 
B 2 89  ALA 89  259 259 ALA ALA B . n 
B 2 90  ALA 90  260 260 ALA ALA B . n 
B 2 91  MET 91  261 261 MET MET B . n 
B 2 92  LEU 92  262 262 LEU LEU B . n 
B 2 93  LEU 93  263 263 LEU LEU B . n 
B 2 94  ALA 94  264 264 ALA ALA B . n 
B 2 95  SER 95  265 265 SER SER B . n 
B 2 96  LYS 96  266 266 LYS LYS B . n 
B 2 97  PHE 97  267 267 PHE PHE B . n 
B 2 98  GLU 98  268 268 GLU GLU B . n 
B 2 99  GLU 99  269 269 GLU GLU B . n 
B 2 100 ILE 100 270 270 ILE ILE B . n 
B 2 101 TYR 101 271 271 TYR TYR B . n 
B 2 102 PRO 102 272 272 PRO PRO B . n 
B 2 103 PRO 103 273 273 PRO PRO B . n 
B 2 104 GLU 104 274 274 GLU GLU B . n 
B 2 105 VAL 105 275 275 VAL VAL B . n 
B 2 106 ALA 106 276 276 ALA ALA B . n 
B 2 107 GLU 107 277 277 GLU GLU B . n 
B 2 108 PHE 108 278 278 PHE PHE B . n 
B 2 109 VAL 109 279 279 VAL VAL B . n 
B 2 110 TYR 110 280 280 TYR TYR B . n 
B 2 111 ILE 111 281 281 ILE ILE B . n 
B 2 112 THR 112 282 282 THR THR B . n 
B 2 113 ASP 113 283 283 ASP ASP B . n 
B 2 114 ASP 114 284 284 ASP ASP B . n 
B 2 115 THR 115 285 285 THR THR B . n 
B 2 116 TYR 116 286 286 TYR TYR B . n 
B 2 117 THR 117 287 287 THR THR B . n 
B 2 118 LYS 118 288 288 LYS LYS B . n 
B 2 119 LYS 119 289 289 LYS LYS B . n 
B 2 120 GLN 120 290 290 GLN GLN B . n 
B 2 121 VAL 121 291 291 VAL VAL B . n 
B 2 122 LEU 122 292 292 LEU LEU B . n 
B 2 123 ARG 123 293 293 ARG ARG B . n 
B 2 124 MET 124 294 294 MET MET B . n 
B 2 125 GLU 125 295 295 GLU GLU B . n 
B 2 126 HIS 126 296 296 HIS HIS B . n 
B 2 127 LEU 127 297 297 LEU LEU B . n 
B 2 128 VAL 128 298 298 VAL VAL B . n 
B 2 129 LEU 129 299 299 LEU LEU B . n 
B 2 130 LYS 130 300 300 LYS LYS B . n 
B 2 131 VAL 131 301 301 VAL VAL B . n 
B 2 132 LEU 132 302 302 LEU LEU B . n 
B 2 133 ALA 133 303 303 ALA ALA B . n 
B 2 134 PHE 134 304 304 PHE PHE B . n 
B 2 135 ASP 135 305 305 ASP ASP B . n 
B 2 136 LEU 136 306 306 LEU LEU B . n 
B 2 137 ALA 137 307 307 ALA ALA B . n 
B 2 138 ALA 138 308 308 ALA ALA B . n 
B 2 139 PRO 139 309 309 PRO PRO B . n 
B 2 140 THR 140 310 310 THR THR B . n 
B 2 141 ILE 141 311 311 ILE ILE B . n 
B 2 142 ASN 142 312 312 ASN ASN B . n 
B 2 143 GLN 143 313 313 GLN GLN B . n 
B 2 144 PHE 144 314 314 PHE PHE B . n 
B 2 145 LEU 145 315 315 LEU LEU B . n 
B 2 146 THR 146 316 316 THR THR B . n 
B 2 147 GLN 147 317 317 GLN GLN B . n 
B 2 148 TYR 148 318 318 TYR TYR B . n 
B 2 149 PHE 149 319 319 PHE PHE B . n 
B 2 150 LEU 150 320 320 LEU LEU B . n 
B 2 151 HIS 151 321 321 HIS HIS B . n 
B 2 152 GLN 152 322 322 GLN GLN B . n 
B 2 153 GLN 153 323 323 GLN GLN B . n 
B 2 154 PRO 154 324 324 PRO PRO B . n 
B 2 155 ALA 155 325 325 ALA ALA B . n 
B 2 156 ASN 156 326 326 ASN ASN B . n 
B 2 157 CYS 157 327 327 CYS CYS B . n 
B 2 158 LYS 158 328 328 LYS LYS B . n 
B 2 159 VAL 159 329 329 VAL VAL B . n 
B 2 160 GLU 160 330 330 GLU GLU B . n 
B 2 161 SER 161 331 331 SER SER B . n 
B 2 162 LEU 162 332 332 LEU LEU B . n 
B 2 163 ALA 163 333 333 ALA ALA B . n 
B 2 164 MET 164 334 334 MET MET B . n 
B 2 165 PHE 165 335 335 PHE PHE B . n 
B 2 166 LEU 166 336 336 LEU LEU B . n 
B 2 167 GLY 167 337 337 GLY GLY B . n 
B 2 168 GLU 168 338 338 GLU GLU B . n 
B 2 169 LEU 169 339 339 LEU LEU B . n 
B 2 170 SER 170 340 340 SER SER B . n 
B 2 171 LEU 171 341 341 LEU LEU B . n 
B 2 172 ILE 172 342 342 ILE ILE B . n 
B 2 173 ASP 173 343 343 ASP ASP B . n 
B 2 174 ALA 174 344 344 ALA ALA B . n 
B 2 175 ASP 175 345 345 ASP ASP B . n 
B 2 176 PRO 176 346 346 PRO PRO B . n 
B 2 177 TYR 177 347 347 TYR TYR B . n 
B 2 178 LEU 178 348 348 LEU LEU B . n 
B 2 179 LYS 179 349 349 LYS LYS B . n 
B 2 180 TYR 180 350 350 TYR TYR B . n 
B 2 181 LEU 181 351 351 LEU LEU B . n 
B 2 182 PRO 182 352 352 PRO PRO B . n 
B 2 183 SER 183 353 353 SER SER B . n 
B 2 184 VAL 184 354 354 VAL VAL B . n 
B 2 185 ILE 185 355 355 ILE ILE B . n 
B 2 186 ALA 186 356 356 ALA ALA B . n 
B 2 187 ALA 187 357 357 ALA ALA B . n 
B 2 188 ALA 188 358 358 ALA ALA B . n 
B 2 189 ALA 189 359 359 ALA ALA B . n 
B 2 190 PHE 190 360 360 PHE PHE B . n 
B 2 191 HIS 191 361 361 HIS HIS B . n 
B 2 192 LEU 192 362 362 LEU LEU B . n 
B 2 193 ALA 193 363 363 ALA ALA B . n 
B 2 194 LEU 194 364 364 LEU LEU B . n 
B 2 195 TYR 195 365 365 TYR TYR B . n 
B 2 196 THR 196 366 366 THR THR B . n 
B 2 197 VAL 197 367 367 VAL VAL B . n 
B 2 198 THR 198 368 368 THR THR B . n 
B 2 199 GLY 199 369 369 GLY GLY B . n 
B 2 200 GLN 200 370 370 GLN GLN B . n 
B 2 201 SER 201 371 371 SER SER B . n 
B 2 202 TRP 202 372 372 TRP TRP B . n 
B 2 203 PRO 203 373 373 PRO PRO B . n 
B 2 204 GLU 204 374 374 GLU GLU B . n 
B 2 205 SER 205 375 375 SER SER B . n 
B 2 206 LEU 206 376 376 LEU LEU B . n 
B 2 207 VAL 207 377 377 VAL VAL B . n 
B 2 208 GLN 208 378 378 GLN GLN B . n 
B 2 209 LYS 209 379 379 LYS LYS B . n 
B 2 210 THR 210 380 380 THR THR B . n 
B 2 211 GLY 211 381 381 GLY GLY B . n 
B 2 212 TYR 212 382 382 TYR TYR B . n 
B 2 213 THR 213 383 383 THR THR B . n 
B 2 214 LEU 214 384 384 LEU LEU B . n 
B 2 215 GLU 215 385 385 GLU GLU B . n 
B 2 216 THR 216 386 386 THR THR B . n 
B 2 217 LEU 217 387 387 LEU LEU B . n 
B 2 218 LYS 218 388 388 LYS LYS B . n 
B 2 219 PRO 219 389 389 PRO PRO B . n 
B 2 220 CYS 220 390 390 CYS CYS B . n 
B 2 221 LEU 221 391 391 LEU LEU B . n 
B 2 222 LEU 222 392 392 LEU LEU B . n 
B 2 223 ASP 223 393 393 ASP ASP B . n 
B 2 224 LEU 224 394 394 LEU LEU B . n 
B 2 225 HIS 225 395 395 HIS HIS B . n 
B 2 226 GLN 226 396 396 GLN GLN B . n 
B 2 227 THR 227 397 397 THR THR B . n 
B 2 228 TYR 228 398 398 TYR TYR B . n 
B 2 229 LEU 229 399 399 LEU LEU B . n 
B 2 230 ARG 230 400 400 ARG ARG B . n 
B 2 231 ALA 231 401 401 ALA ALA B . n 
B 2 232 PRO 232 402 402 PRO PRO B . n 
B 2 233 GLN 233 403 403 GLN GLN B . n 
B 2 234 HIS 234 404 404 HIS HIS B . n 
B 2 235 ALA 235 405 405 ALA ALA B . n 
B 2 236 GLN 236 406 406 GLN GLN B . n 
B 2 237 GLN 237 407 407 GLN GLN B . n 
B 2 238 SER 238 408 408 SER SER B . n 
B 2 239 ILE 239 409 409 ILE ILE B . n 
B 2 240 ARG 240 410 410 ARG ARG B . n 
B 2 241 GLU 241 411 411 GLU GLU B . n 
B 2 242 LYS 242 412 412 LYS LYS B . n 
B 2 243 TYR 243 413 413 TYR TYR B . n 
B 2 244 LYS 244 414 414 LYS LYS B . n 
B 2 245 ASN 245 415 415 ASN ASN B . n 
B 2 246 SER 246 416 416 SER SER B . n 
B 2 247 LYS 247 417 417 LYS LYS B . n 
B 2 248 TYR 248 418 418 TYR TYR B . n 
B 2 249 HIS 249 419 419 HIS HIS B . n 
B 2 250 GLY 250 420 420 GLY GLY B . n 
B 2 251 VAL 251 421 421 VAL VAL B . n 
B 2 252 SER 252 422 422 SER SER B . n 
B 2 253 LEU 253 423 423 LEU LEU B . n 
B 2 254 LEU 254 424 424 LEU LEU B . n 
B 2 255 ASN 255 425 425 ASN ASN B . n 
B 2 256 PRO 256 426 426 PRO PRO B . n 
B 2 257 PRO 257 427 427 PRO PRO B . n 
B 2 258 GLU 258 428 428 GLU GLU B . n 
B 2 259 THR 259 429 429 THR THR B . n 
B 2 260 LEU 260 430 430 LEU LEU B . n 
B 2 261 ASN 261 431 431 ASN ASN B . n 
B 2 262 VAL 262 432 432 VAL VAL B . n 
B 2 263 HIS 263 433 ?   ?   ?   B . n 
B 2 264 HIS 264 434 ?   ?   ?   B . n 
B 2 265 HIS 265 435 ?   ?   ?   B . n 
B 2 266 HIS 266 436 ?   ?   ?   B . n 
B 2 267 HIS 267 437 ?   ?   ?   B . n 
B 2 268 HIS 268 438 ?   ?   ?   B . n 
C 1 1   GLY 1   -3  ?   ?   ?   C . n 
C 1 2   PRO 2   -2  ?   ?   ?   C . n 
C 1 3   GLY 3   -1  ?   ?   ?   C . n 
C 1 4   SER 4   0   0   SER SER C . n 
C 1 5   MET 5   1   1   MET MET C . n 
C 1 6   GLU 6   2   2   GLU GLU C . n 
C 1 7   ASN 7   3   3   ASN ASN C . n 
C 1 8   PHE 8   4   4   PHE PHE C . n 
C 1 9   GLN 9   5   5   GLN GLN C . n 
C 1 10  LYS 10  6   6   LYS LYS C . n 
C 1 11  VAL 11  7   7   VAL VAL C . n 
C 1 12  GLU 12  8   8   GLU GLU C . n 
C 1 13  LYS 13  9   9   LYS LYS C . n 
C 1 14  ILE 14  10  10  ILE ILE C . n 
C 1 15  GLY 15  11  11  GLY GLY C . n 
C 1 16  GLU 16  12  12  GLU GLU C . n 
C 1 17  GLY 17  13  13  GLY GLY C . n 
C 1 18  THR 18  14  14  THR THR C . n 
C 1 19  TYR 19  15  15  TYR TYR C . n 
C 1 20  GLY 20  16  16  GLY GLY C . n 
C 1 21  VAL 21  17  17  VAL VAL C . n 
C 1 22  VAL 22  18  18  VAL VAL C . n 
C 1 23  TYR 23  19  19  TYR TYR C . n 
C 1 24  LYS 24  20  20  LYS LYS C . n 
C 1 25  ALA 25  21  21  ALA ALA C . n 
C 1 26  ARG 26  22  22  ARG ARG C . n 
C 1 27  ASN 27  23  23  ASN ASN C . n 
C 1 28  LYS 28  24  24  LYS LYS C . n 
C 1 29  LEU 29  25  25  LEU LEU C . n 
C 1 30  THR 30  26  26  THR THR C . n 
C 1 31  GLY 31  27  27  GLY GLY C . n 
C 1 32  GLU 32  28  28  GLU GLU C . n 
C 1 33  VAL 33  29  29  VAL VAL C . n 
C 1 34  VAL 34  30  30  VAL VAL C . n 
C 1 35  ALA 35  31  31  ALA ALA C . n 
C 1 36  LEU 36  32  32  LEU LEU C . n 
C 1 37  LYS 37  33  33  LYS LYS C . n 
C 1 38  LYS 38  34  34  LYS LYS C . n 
C 1 39  ILE 39  35  35  ILE ILE C . n 
C 1 40  ARG 40  36  36  ARG ARG C . n 
C 1 41  LEU 41  37  37  LEU LEU C . n 
C 1 42  ASP 42  38  38  ASP ASP C . n 
C 1 43  THR 43  39  39  THR THR C . n 
C 1 44  GLU 44  40  40  GLU GLU C . n 
C 1 45  THR 45  41  41  THR THR C . n 
C 1 46  GLU 46  42  42  GLU GLU C . n 
C 1 47  GLY 47  43  43  GLY GLY C . n 
C 1 48  VAL 48  44  44  VAL VAL C . n 
C 1 49  PRO 49  45  45  PRO PRO C . n 
C 1 50  SER 50  46  46  SER SER C . n 
C 1 51  THR 51  47  47  THR THR C . n 
C 1 52  ALA 52  48  48  ALA ALA C . n 
C 1 53  ILE 53  49  49  ILE ILE C . n 
C 1 54  ARG 54  50  50  ARG ARG C . n 
C 1 55  GLU 55  51  51  GLU GLU C . n 
C 1 56  ILE 56  52  52  ILE ILE C . n 
C 1 57  SER 57  53  53  SER SER C . n 
C 1 58  LEU 58  54  54  LEU LEU C . n 
C 1 59  LEU 59  55  55  LEU LEU C . n 
C 1 60  LYS 60  56  56  LYS LYS C . n 
C 1 61  GLU 61  57  57  GLU GLU C . n 
C 1 62  LEU 62  58  58  LEU LEU C . n 
C 1 63  ASN 63  59  59  ASN ASN C . n 
C 1 64  HIS 64  60  60  HIS HIS C . n 
C 1 65  PRO 65  61  61  PRO PRO C . n 
C 1 66  ASN 66  62  62  ASN ASN C . n 
C 1 67  ILE 67  63  63  ILE ILE C . n 
C 1 68  VAL 68  64  64  VAL VAL C . n 
C 1 69  LYS 69  65  65  LYS LYS C . n 
C 1 70  LEU 70  66  66  LEU LEU C . n 
C 1 71  LEU 71  67  67  LEU LEU C . n 
C 1 72  ASP 72  68  68  ASP ASP C . n 
C 1 73  VAL 73  69  69  VAL VAL C . n 
C 1 74  ILE 74  70  70  ILE ILE C . n 
C 1 75  HIS 75  71  71  HIS HIS C . n 
C 1 76  THR 76  72  72  THR THR C . n 
C 1 77  GLU 77  73  73  GLU GLU C . n 
C 1 78  ASN 78  74  74  ASN ASN C . n 
C 1 79  LYS 79  75  75  LYS LYS C . n 
C 1 80  LEU 80  76  76  LEU LEU C . n 
C 1 81  TYR 81  77  77  TYR TYR C . n 
C 1 82  LEU 82  78  78  LEU LEU C . n 
C 1 83  VAL 83  79  79  VAL VAL C . n 
C 1 84  PHE 84  80  80  PHE PHE C . n 
C 1 85  GLU 85  81  81  GLU GLU C . n 
C 1 86  PHE 86  82  82  PHE PHE C . n 
C 1 87  LEU 87  83  83  LEU LEU C . n 
C 1 88  HIS 88  84  84  HIS HIS C . n 
C 1 89  GLN 89  85  85  GLN GLN C . n 
C 1 90  ASP 90  86  86  ASP ASP C . n 
C 1 91  LEU 91  87  87  LEU LEU C . n 
C 1 92  LYS 92  88  88  LYS LYS C . n 
C 1 93  LYS 93  89  89  LYS LYS C . n 
C 1 94  PHE 94  90  90  PHE PHE C . n 
C 1 95  MET 95  91  91  MET MET C . n 
C 1 96  ASP 96  92  92  ASP ASP C . n 
C 1 97  ALA 97  93  93  ALA ALA C . n 
C 1 98  SER 98  94  94  SER SER C . n 
C 1 99  ALA 99  95  95  ALA ALA C . n 
C 1 100 LEU 100 96  96  LEU LEU C . n 
C 1 101 THR 101 97  97  THR THR C . n 
C 1 102 GLY 102 98  98  GLY GLY C . n 
C 1 103 ILE 103 99  99  ILE ILE C . n 
C 1 104 PRO 104 100 100 PRO PRO C . n 
C 1 105 LEU 105 101 101 LEU LEU C . n 
C 1 106 PRO 106 102 102 PRO PRO C . n 
C 1 107 LEU 107 103 103 LEU LEU C . n 
C 1 108 ILE 108 104 104 ILE ILE C . n 
C 1 109 LYS 109 105 105 LYS LYS C . n 
C 1 110 SER 110 106 106 SER SER C . n 
C 1 111 TYR 111 107 107 TYR TYR C . n 
C 1 112 LEU 112 108 108 LEU LEU C . n 
C 1 113 PHE 113 109 109 PHE PHE C . n 
C 1 114 GLN 114 110 110 GLN GLN C . n 
C 1 115 LEU 115 111 111 LEU LEU C . n 
C 1 116 LEU 116 112 112 LEU LEU C . n 
C 1 117 GLN 117 113 113 GLN GLN C . n 
C 1 118 GLY 118 114 114 GLY GLY C . n 
C 1 119 LEU 119 115 115 LEU LEU C . n 
C 1 120 ALA 120 116 116 ALA ALA C . n 
C 1 121 PHE 121 117 117 PHE PHE C . n 
C 1 122 CYS 122 118 118 CYS CYS C . n 
C 1 123 HIS 123 119 119 HIS HIS C . n 
C 1 124 SER 124 120 120 SER SER C . n 
C 1 125 HIS 125 121 121 HIS HIS C . n 
C 1 126 ARG 126 122 122 ARG ARG C . n 
C 1 127 VAL 127 123 123 VAL VAL C . n 
C 1 128 LEU 128 124 124 LEU LEU C . n 
C 1 129 HIS 129 125 125 HIS HIS C . n 
C 1 130 ARG 130 126 126 ARG ARG C . n 
C 1 131 ASP 131 127 127 ASP ASP C . n 
C 1 132 LEU 132 128 128 LEU LEU C . n 
C 1 133 LYS 133 129 129 LYS LYS C . n 
C 1 134 PRO 134 130 130 PRO PRO C . n 
C 1 135 GLN 135 131 131 GLN GLN C . n 
C 1 136 ASN 136 132 132 ASN ASN C . n 
C 1 137 LEU 137 133 133 LEU LEU C . n 
C 1 138 LEU 138 134 134 LEU LEU C . n 
C 1 139 ILE 139 135 135 ILE ILE C . n 
C 1 140 ASN 140 136 136 ASN ASN C . n 
C 1 141 THR 141 137 137 THR THR C . n 
C 1 142 GLU 142 138 138 GLU GLU C . n 
C 1 143 GLY 143 139 139 GLY GLY C . n 
C 1 144 ALA 144 140 140 ALA ALA C . n 
C 1 145 ILE 145 141 141 ILE ILE C . n 
C 1 146 LYS 146 142 142 LYS LYS C . n 
C 1 147 LEU 147 143 143 LEU LEU C . n 
C 1 148 ALA 148 144 144 ALA ALA C . n 
C 1 149 ASP 149 145 145 ASP ASP C . n 
C 1 150 PHE 150 146 146 PHE PHE C . n 
C 1 151 GLY 151 147 147 GLY GLY C . n 
C 1 152 LEU 152 148 148 LEU LEU C . n 
C 1 153 ALA 153 149 149 ALA ALA C . n 
C 1 154 ARG 154 150 150 ARG ARG C . n 
C 1 155 ALA 155 151 151 ALA ALA C . n 
C 1 156 PHE 156 152 152 PHE PHE C . n 
C 1 157 GLY 157 153 153 GLY GLY C . n 
C 1 158 VAL 158 154 154 VAL VAL C . n 
C 1 159 PRO 159 155 155 PRO PRO C . n 
C 1 160 VAL 160 156 156 VAL VAL C . n 
C 1 161 ARG 161 157 157 ARG ARG C . n 
C 1 162 THR 162 158 158 THR THR C . n 
C 1 163 TYR 163 159 159 TYR TYR C . n 
C 1 164 TPO 164 160 160 TPO TPO C . n 
C 1 165 HIS 165 161 161 HIS HIS C . n 
C 1 166 GLU 166 162 162 GLU GLU C . n 
C 1 167 VAL 167 163 163 VAL VAL C . n 
C 1 168 VAL 168 164 164 VAL VAL C . n 
C 1 169 THR 169 165 165 THR THR C . n 
C 1 170 LEU 170 166 166 LEU LEU C . n 
C 1 171 TRP 171 167 167 TRP TRP C . n 
C 1 172 TYR 172 168 168 TYR TYR C . n 
C 1 173 ARG 173 169 169 ARG ARG C . n 
C 1 174 ALA 174 170 170 ALA ALA C . n 
C 1 175 PRO 175 171 171 PRO PRO C . n 
C 1 176 GLU 176 172 172 GLU GLU C . n 
C 1 177 ILE 177 173 173 ILE ILE C . n 
C 1 178 LEU 178 174 174 LEU LEU C . n 
C 1 179 LEU 179 175 175 LEU LEU C . n 
C 1 180 GLY 180 176 176 GLY GLY C . n 
C 1 181 CYS 181 177 177 CYS CYS C . n 
C 1 182 LYS 182 178 178 LYS LYS C . n 
C 1 183 TYR 183 179 179 TYR TYR C . n 
C 1 184 TYR 184 180 180 TYR TYR C . n 
C 1 185 SER 185 181 181 SER SER C . n 
C 1 186 THR 186 182 182 THR THR C . n 
C 1 187 ALA 187 183 183 ALA ALA C . n 
C 1 188 VAL 188 184 184 VAL VAL C . n 
C 1 189 ASP 189 185 185 ASP ASP C . n 
C 1 190 ILE 190 186 186 ILE ILE C . n 
C 1 191 TRP 191 187 187 TRP TRP C . n 
C 1 192 SER 192 188 188 SER SER C . n 
C 1 193 LEU 193 189 189 LEU LEU C . n 
C 1 194 GLY 194 190 190 GLY GLY C . n 
C 1 195 CYS 195 191 191 CYS CYS C . n 
C 1 196 ILE 196 192 192 ILE ILE C . n 
C 1 197 PHE 197 193 193 PHE PHE C . n 
C 1 198 ALA 198 194 194 ALA ALA C . n 
C 1 199 GLU 199 195 195 GLU GLU C . n 
C 1 200 MET 200 196 196 MET MET C . n 
C 1 201 VAL 201 197 197 VAL VAL C . n 
C 1 202 THR 202 198 198 THR THR C . n 
C 1 203 ARG 203 199 199 ARG ARG C . n 
C 1 204 ARG 204 200 200 ARG ARG C . n 
C 1 205 ALA 205 201 201 ALA ALA C . n 
C 1 206 LEU 206 202 202 LEU LEU C . n 
C 1 207 PHE 207 203 203 PHE PHE C . n 
C 1 208 PRO 208 204 204 PRO PRO C . n 
C 1 209 GLY 209 205 205 GLY GLY C . n 
C 1 210 ASP 210 206 206 ASP ASP C . n 
C 1 211 SER 211 207 207 SER SER C . n 
C 1 212 GLU 212 208 208 GLU GLU C . n 
C 1 213 ILE 213 209 209 ILE ILE C . n 
C 1 214 ASP 214 210 210 ASP ASP C . n 
C 1 215 GLN 215 211 211 GLN GLN C . n 
C 1 216 LEU 216 212 212 LEU LEU C . n 
C 1 217 PHE 217 213 213 PHE PHE C . n 
C 1 218 ARG 218 214 214 ARG ARG C . n 
C 1 219 ILE 219 215 215 ILE ILE C . n 
C 1 220 PHE 220 216 216 PHE PHE C . n 
C 1 221 ARG 221 217 217 ARG ARG C . n 
C 1 222 THR 222 218 218 THR THR C . n 
C 1 223 LEU 223 219 219 LEU LEU C . n 
C 1 224 GLY 224 220 220 GLY GLY C . n 
C 1 225 THR 225 221 221 THR THR C . n 
C 1 226 PRO 226 222 222 PRO PRO C . n 
C 1 227 ASP 227 223 223 ASP ASP C . n 
C 1 228 GLU 228 224 224 GLU GLU C . n 
C 1 229 VAL 229 225 225 VAL VAL C . n 
C 1 230 VAL 230 226 226 VAL VAL C . n 
C 1 231 TRP 231 227 227 TRP TRP C . n 
C 1 232 PRO 232 228 228 PRO PRO C . n 
C 1 233 GLY 233 229 229 GLY GLY C . n 
C 1 234 VAL 234 230 230 VAL VAL C . n 
C 1 235 THR 235 231 231 THR THR C . n 
C 1 236 SER 236 232 232 SER SER C . n 
C 1 237 MET 237 233 233 MET MET C . n 
C 1 238 PRO 238 234 234 PRO PRO C . n 
C 1 239 ASP 239 235 235 ASP ASP C . n 
C 1 240 TYR 240 236 236 TYR TYR C . n 
C 1 241 LYS 241 237 237 LYS LYS C . n 
C 1 242 PRO 242 238 238 PRO PRO C . n 
C 1 243 SER 243 239 239 SER SER C . n 
C 1 244 PHE 244 240 240 PHE PHE C . n 
C 1 245 PRO 245 241 241 PRO PRO C . n 
C 1 246 LYS 246 242 242 LYS LYS C . n 
C 1 247 TRP 247 243 243 TRP TRP C . n 
C 1 248 ALA 248 244 244 ALA ALA C . n 
C 1 249 ARG 249 245 245 ARG ARG C . n 
C 1 250 GLN 250 246 246 GLN GLN C . n 
C 1 251 ASP 251 247 247 ASP ASP C . n 
C 1 252 PHE 252 248 248 PHE PHE C . n 
C 1 253 SER 253 249 249 SER SER C . n 
C 1 254 LYS 254 250 250 LYS LYS C . n 
C 1 255 VAL 255 251 251 VAL VAL C . n 
C 1 256 VAL 256 252 252 VAL VAL C . n 
C 1 257 PRO 257 253 253 PRO PRO C . n 
C 1 258 PRO 258 254 254 PRO PRO C . n 
C 1 259 LEU 259 255 255 LEU LEU C . n 
C 1 260 ASP 260 256 256 ASP ASP C . n 
C 1 261 GLU 261 257 257 GLU GLU C . n 
C 1 262 ASP 262 258 258 ASP ASP C . n 
C 1 263 GLY 263 259 259 GLY GLY C . n 
C 1 264 ARG 264 260 260 ARG ARG C . n 
C 1 265 SER 265 261 261 SER SER C . n 
C 1 266 LEU 266 262 262 LEU LEU C . n 
C 1 267 LEU 267 263 263 LEU LEU C . n 
C 1 268 SER 268 264 264 SER SER C . n 
C 1 269 GLN 269 265 265 GLN GLN C . n 
C 1 270 MET 270 266 266 MET MET C . n 
C 1 271 LEU 271 267 267 LEU LEU C . n 
C 1 272 HIS 272 268 268 HIS HIS C . n 
C 1 273 TYR 273 269 269 TYR TYR C . n 
C 1 274 ASP 274 270 270 ASP ASP C . n 
C 1 275 PRO 275 271 271 PRO PRO C . n 
C 1 276 ASN 276 272 272 ASN ASN C . n 
C 1 277 LYS 277 273 273 LYS LYS C . n 
C 1 278 ARG 278 274 274 ARG ARG C . n 
C 1 279 ILE 279 275 275 ILE ILE C . n 
C 1 280 SER 280 276 276 SER SER C . n 
C 1 281 ALA 281 277 277 ALA ALA C . n 
C 1 282 LYS 282 278 278 LYS LYS C . n 
C 1 283 ALA 283 279 279 ALA ALA C . n 
C 1 284 ALA 284 280 280 ALA ALA C . n 
C 1 285 LEU 285 281 281 LEU LEU C . n 
C 1 286 ALA 286 282 282 ALA ALA C . n 
C 1 287 HIS 287 283 283 HIS HIS C . n 
C 1 288 PRO 288 284 284 PRO PRO C . n 
C 1 289 PHE 289 285 285 PHE PHE C . n 
C 1 290 PHE 290 286 286 PHE PHE C . n 
C 1 291 GLN 291 287 287 GLN GLN C . n 
C 1 292 ASP 292 288 288 ASP ASP C . n 
C 1 293 VAL 293 289 289 VAL VAL C . n 
C 1 294 THR 294 290 290 THR THR C . n 
C 1 295 LYS 295 291 291 LYS LYS C . n 
C 1 296 PRO 296 292 292 PRO PRO C . n 
C 1 297 VAL 297 293 293 VAL VAL C . n 
C 1 298 PRO 298 294 294 PRO PRO C . n 
C 1 299 HIS 299 295 295 HIS HIS C . n 
C 1 300 LEU 300 296 296 LEU LEU C . n 
C 1 301 ARG 301 297 ?   ?   ?   C . n 
C 1 302 LEU 302 298 ?   ?   ?   C . n 
D 2 1   GLY 1   171 171 GLY GLY D . n 
D 2 2   VAL 2   172 172 VAL VAL D . n 
D 2 3   ASN 3   173 173 ASN ASN D . n 
D 2 4   GLU 4   174 174 GLU GLU D . n 
D 2 5   VAL 5   175 175 VAL VAL D . n 
D 2 6   PRO 6   176 176 PRO PRO D . n 
D 2 7   ASP 7   177 177 ASP ASP D . n 
D 2 8   TYR 8   178 178 TYR TYR D . n 
D 2 9   HIS 9   179 179 HIS HIS D . n 
D 2 10  GLU 10  180 180 GLU GLU D . n 
D 2 11  ASP 11  181 181 ASP ASP D . n 
D 2 12  ILE 12  182 182 ILE ILE D . n 
D 2 13  HIS 13  183 183 HIS HIS D . n 
D 2 14  THR 14  184 184 THR THR D . n 
D 2 15  TYR 15  185 185 TYR TYR D . n 
D 2 16  LEU 16  186 186 LEU LEU D . n 
D 2 17  ARG 17  187 187 ARG ARG D . n 
D 2 18  GLU 18  188 188 GLU GLU D . n 
D 2 19  MET 19  189 189 MET MET D . n 
D 2 20  GLU 20  190 190 GLU GLU D . n 
D 2 21  VAL 21  191 191 VAL VAL D . n 
D 2 22  LYS 22  192 192 LYS LYS D . n 
D 2 23  CYS 23  193 193 CYS CYS D . n 
D 2 24  LYS 24  194 194 LYS LYS D . n 
D 2 25  PRO 25  195 195 PRO PRO D . n 
D 2 26  LYS 26  196 196 LYS LYS D . n 
D 2 27  VAL 27  197 197 VAL VAL D . n 
D 2 28  GLY 28  198 198 GLY GLY D . n 
D 2 29  TYR 29  199 199 TYR TYR D . n 
D 2 30  MET 30  200 200 MET MET D . n 
D 2 31  LYS 31  201 201 LYS LYS D . n 
D 2 32  LYS 32  202 202 LYS LYS D . n 
D 2 33  GLN 33  203 203 GLN GLN D . n 
D 2 34  PRO 34  204 204 PRO PRO D . n 
D 2 35  ASP 35  205 205 ASP ASP D . n 
D 2 36  ILE 36  206 206 ILE ILE D . n 
D 2 37  THR 37  207 207 THR THR D . n 
D 2 38  ASN 38  208 208 ASN ASN D . n 
D 2 39  SER 39  209 209 SER SER D . n 
D 2 40  MET 40  210 210 MET MET D . n 
D 2 41  ARG 41  211 211 ARG ARG D . n 
D 2 42  ALA 42  212 212 ALA ALA D . n 
D 2 43  ILE 43  213 213 ILE ILE D . n 
D 2 44  LEU 44  214 214 LEU LEU D . n 
D 2 45  VAL 45  215 215 VAL VAL D . n 
D 2 46  ASP 46  216 216 ASP ASP D . n 
D 2 47  TRP 47  217 217 TRP TRP D . n 
D 2 48  LEU 48  218 218 LEU LEU D . n 
D 2 49  VAL 49  219 219 VAL VAL D . n 
D 2 50  GLU 50  220 220 GLU GLU D . n 
D 2 51  VAL 51  221 221 VAL VAL D . n 
D 2 52  GLY 52  222 222 GLY GLY D . n 
D 2 53  GLU 53  223 223 GLU GLU D . n 
D 2 54  GLU 54  224 224 GLU GLU D . n 
D 2 55  TYR 55  225 225 TYR TYR D . n 
D 2 56  LYS 56  226 226 LYS LYS D . n 
D 2 57  LEU 57  227 227 LEU LEU D . n 
D 2 58  GLN 58  228 228 GLN GLN D . n 
D 2 59  ASN 59  229 229 ASN ASN D . n 
D 2 60  GLU 60  230 230 GLU GLU D . n 
D 2 61  THR 61  231 231 THR THR D . n 
D 2 62  LEU 62  232 232 LEU LEU D . n 
D 2 63  HIS 63  233 233 HIS HIS D . n 
D 2 64  LEU 64  234 234 LEU LEU D . n 
D 2 65  ALA 65  235 235 ALA ALA D . n 
D 2 66  VAL 66  236 236 VAL VAL D . n 
D 2 67  ASN 67  237 237 ASN ASN D . n 
D 2 68  TYR 68  238 238 TYR TYR D . n 
D 2 69  ILE 69  239 239 ILE ILE D . n 
D 2 70  ASP 70  240 240 ASP ASP D . n 
D 2 71  ARG 71  241 241 ARG ARG D . n 
D 2 72  PHE 72  242 242 PHE PHE D . n 
D 2 73  LEU 73  243 243 LEU LEU D . n 
D 2 74  SER 74  244 244 SER SER D . n 
D 2 75  SER 75  245 245 SER SER D . n 
D 2 76  MET 76  246 246 MET MET D . n 
D 2 77  SER 77  247 247 SER SER D . n 
D 2 78  VAL 78  248 248 VAL VAL D . n 
D 2 79  LEU 79  249 249 LEU LEU D . n 
D 2 80  ARG 80  250 250 ARG ARG D . n 
D 2 81  GLY 81  251 251 GLY GLY D . n 
D 2 82  LYS 82  252 252 LYS LYS D . n 
D 2 83  LEU 83  253 253 LEU LEU D . n 
D 2 84  GLN 84  254 254 GLN GLN D . n 
D 2 85  LEU 85  255 255 LEU LEU D . n 
D 2 86  VAL 86  256 256 VAL VAL D . n 
D 2 87  GLY 87  257 257 GLY GLY D . n 
D 2 88  THR 88  258 258 THR THR D . n 
D 2 89  ALA 89  259 259 ALA ALA D . n 
D 2 90  ALA 90  260 260 ALA ALA D . n 
D 2 91  MET 91  261 261 MET MET D . n 
D 2 92  LEU 92  262 262 LEU LEU D . n 
D 2 93  LEU 93  263 263 LEU LEU D . n 
D 2 94  ALA 94  264 264 ALA ALA D . n 
D 2 95  SER 95  265 265 SER SER D . n 
D 2 96  LYS 96  266 266 LYS LYS D . n 
D 2 97  PHE 97  267 267 PHE PHE D . n 
D 2 98  GLU 98  268 268 GLU GLU D . n 
D 2 99  GLU 99  269 269 GLU GLU D . n 
D 2 100 ILE 100 270 270 ILE ILE D . n 
D 2 101 TYR 101 271 271 TYR TYR D . n 
D 2 102 PRO 102 272 272 PRO PRO D . n 
D 2 103 PRO 103 273 273 PRO PRO D . n 
D 2 104 GLU 104 274 274 GLU GLU D . n 
D 2 105 VAL 105 275 275 VAL VAL D . n 
D 2 106 ALA 106 276 276 ALA ALA D . n 
D 2 107 GLU 107 277 277 GLU GLU D . n 
D 2 108 PHE 108 278 278 PHE PHE D . n 
D 2 109 VAL 109 279 279 VAL VAL D . n 
D 2 110 TYR 110 280 280 TYR TYR D . n 
D 2 111 ILE 111 281 281 ILE ILE D . n 
D 2 112 THR 112 282 282 THR THR D . n 
D 2 113 ASP 113 283 283 ASP ASP D . n 
D 2 114 ASP 114 284 284 ASP ASP D . n 
D 2 115 THR 115 285 285 THR THR D . n 
D 2 116 TYR 116 286 286 TYR TYR D . n 
D 2 117 THR 117 287 287 THR THR D . n 
D 2 118 LYS 118 288 288 LYS LYS D . n 
D 2 119 LYS 119 289 289 LYS LYS D . n 
D 2 120 GLN 120 290 290 GLN GLN D . n 
D 2 121 VAL 121 291 291 VAL VAL D . n 
D 2 122 LEU 122 292 292 LEU LEU D . n 
D 2 123 ARG 123 293 293 ARG ARG D . n 
D 2 124 MET 124 294 294 MET MET D . n 
D 2 125 GLU 125 295 295 GLU GLU D . n 
D 2 126 HIS 126 296 296 HIS HIS D . n 
D 2 127 LEU 127 297 297 LEU LEU D . n 
D 2 128 VAL 128 298 298 VAL VAL D . n 
D 2 129 LEU 129 299 299 LEU LEU D . n 
D 2 130 LYS 130 300 300 LYS LYS D . n 
D 2 131 VAL 131 301 301 VAL VAL D . n 
D 2 132 LEU 132 302 302 LEU LEU D . n 
D 2 133 ALA 133 303 303 ALA ALA D . n 
D 2 134 PHE 134 304 304 PHE PHE D . n 
D 2 135 ASP 135 305 305 ASP ASP D . n 
D 2 136 LEU 136 306 306 LEU LEU D . n 
D 2 137 ALA 137 307 307 ALA ALA D . n 
D 2 138 ALA 138 308 308 ALA ALA D . n 
D 2 139 PRO 139 309 309 PRO PRO D . n 
D 2 140 THR 140 310 310 THR THR D . n 
D 2 141 ILE 141 311 311 ILE ILE D . n 
D 2 142 ASN 142 312 312 ASN ASN D . n 
D 2 143 GLN 143 313 313 GLN GLN D . n 
D 2 144 PHE 144 314 314 PHE PHE D . n 
D 2 145 LEU 145 315 315 LEU LEU D . n 
D 2 146 THR 146 316 316 THR THR D . n 
D 2 147 GLN 147 317 317 GLN GLN D . n 
D 2 148 TYR 148 318 318 TYR TYR D . n 
D 2 149 PHE 149 319 319 PHE PHE D . n 
D 2 150 LEU 150 320 320 LEU LEU D . n 
D 2 151 HIS 151 321 321 HIS HIS D . n 
D 2 152 GLN 152 322 322 GLN GLN D . n 
D 2 153 GLN 153 323 323 GLN GLN D . n 
D 2 154 PRO 154 324 324 PRO PRO D . n 
D 2 155 ALA 155 325 325 ALA ALA D . n 
D 2 156 ASN 156 326 326 ASN ASN D . n 
D 2 157 CYS 157 327 327 CYS CYS D . n 
D 2 158 LYS 158 328 328 LYS LYS D . n 
D 2 159 VAL 159 329 329 VAL VAL D . n 
D 2 160 GLU 160 330 330 GLU GLU D . n 
D 2 161 SER 161 331 331 SER SER D . n 
D 2 162 LEU 162 332 332 LEU LEU D . n 
D 2 163 ALA 163 333 333 ALA ALA D . n 
D 2 164 MET 164 334 334 MET MET D . n 
D 2 165 PHE 165 335 335 PHE PHE D . n 
D 2 166 LEU 166 336 336 LEU LEU D . n 
D 2 167 GLY 167 337 337 GLY GLY D . n 
D 2 168 GLU 168 338 338 GLU GLU D . n 
D 2 169 LEU 169 339 339 LEU LEU D . n 
D 2 170 SER 170 340 340 SER SER D . n 
D 2 171 LEU 171 341 341 LEU LEU D . n 
D 2 172 ILE 172 342 342 ILE ILE D . n 
D 2 173 ASP 173 343 343 ASP ASP D . n 
D 2 174 ALA 174 344 344 ALA ALA D . n 
D 2 175 ASP 175 345 345 ASP ASP D . n 
D 2 176 PRO 176 346 346 PRO PRO D . n 
D 2 177 TYR 177 347 347 TYR TYR D . n 
D 2 178 LEU 178 348 348 LEU LEU D . n 
D 2 179 LYS 179 349 349 LYS LYS D . n 
D 2 180 TYR 180 350 350 TYR TYR D . n 
D 2 181 LEU 181 351 351 LEU LEU D . n 
D 2 182 PRO 182 352 352 PRO PRO D . n 
D 2 183 SER 183 353 353 SER SER D . n 
D 2 184 VAL 184 354 354 VAL VAL D . n 
D 2 185 ILE 185 355 355 ILE ILE D . n 
D 2 186 ALA 186 356 356 ALA ALA D . n 
D 2 187 ALA 187 357 357 ALA ALA D . n 
D 2 188 ALA 188 358 358 ALA ALA D . n 
D 2 189 ALA 189 359 359 ALA ALA D . n 
D 2 190 PHE 190 360 360 PHE PHE D . n 
D 2 191 HIS 191 361 361 HIS HIS D . n 
D 2 192 LEU 192 362 362 LEU LEU D . n 
D 2 193 ALA 193 363 363 ALA ALA D . n 
D 2 194 LEU 194 364 364 LEU LEU D . n 
D 2 195 TYR 195 365 365 TYR TYR D . n 
D 2 196 THR 196 366 366 THR THR D . n 
D 2 197 VAL 197 367 367 VAL VAL D . n 
D 2 198 THR 198 368 368 THR THR D . n 
D 2 199 GLY 199 369 369 GLY GLY D . n 
D 2 200 GLN 200 370 370 GLN GLN D . n 
D 2 201 SER 201 371 371 SER SER D . n 
D 2 202 TRP 202 372 372 TRP TRP D . n 
D 2 203 PRO 203 373 373 PRO PRO D . n 
D 2 204 GLU 204 374 374 GLU GLU D . n 
D 2 205 SER 205 375 375 SER SER D . n 
D 2 206 LEU 206 376 376 LEU LEU D . n 
D 2 207 VAL 207 377 377 VAL VAL D . n 
D 2 208 GLN 208 378 378 GLN GLN D . n 
D 2 209 LYS 209 379 379 LYS LYS D . n 
D 2 210 THR 210 380 380 THR THR D . n 
D 2 211 GLY 211 381 381 GLY GLY D . n 
D 2 212 TYR 212 382 382 TYR TYR D . n 
D 2 213 THR 213 383 383 THR THR D . n 
D 2 214 LEU 214 384 384 LEU LEU D . n 
D 2 215 GLU 215 385 385 GLU GLU D . n 
D 2 216 THR 216 386 386 THR THR D . n 
D 2 217 LEU 217 387 387 LEU LEU D . n 
D 2 218 LYS 218 388 388 LYS LYS D . n 
D 2 219 PRO 219 389 389 PRO PRO D . n 
D 2 220 CYS 220 390 390 CYS CYS D . n 
D 2 221 LEU 221 391 391 LEU LEU D . n 
D 2 222 LEU 222 392 392 LEU LEU D . n 
D 2 223 ASP 223 393 393 ASP ASP D . n 
D 2 224 LEU 224 394 394 LEU LEU D . n 
D 2 225 HIS 225 395 395 HIS HIS D . n 
D 2 226 GLN 226 396 396 GLN GLN D . n 
D 2 227 THR 227 397 397 THR THR D . n 
D 2 228 TYR 228 398 398 TYR TYR D . n 
D 2 229 LEU 229 399 399 LEU LEU D . n 
D 2 230 ARG 230 400 400 ARG ARG D . n 
D 2 231 ALA 231 401 401 ALA ALA D . n 
D 2 232 PRO 232 402 402 PRO PRO D . n 
D 2 233 GLN 233 403 403 GLN GLN D . n 
D 2 234 HIS 234 404 404 HIS HIS D . n 
D 2 235 ALA 235 405 405 ALA ALA D . n 
D 2 236 GLN 236 406 406 GLN GLN D . n 
D 2 237 GLN 237 407 407 GLN GLN D . n 
D 2 238 SER 238 408 408 SER SER D . n 
D 2 239 ILE 239 409 409 ILE ILE D . n 
D 2 240 ARG 240 410 410 ARG ARG D . n 
D 2 241 GLU 241 411 411 GLU GLU D . n 
D 2 242 LYS 242 412 412 LYS LYS D . n 
D 2 243 TYR 243 413 413 TYR TYR D . n 
D 2 244 LYS 244 414 414 LYS LYS D . n 
D 2 245 ASN 245 415 415 ASN ASN D . n 
D 2 246 SER 246 416 416 SER SER D . n 
D 2 247 LYS 247 417 417 LYS LYS D . n 
D 2 248 TYR 248 418 418 TYR TYR D . n 
D 2 249 HIS 249 419 419 HIS HIS D . n 
D 2 250 GLY 250 420 420 GLY GLY D . n 
D 2 251 VAL 251 421 421 VAL VAL D . n 
D 2 252 SER 252 422 422 SER SER D . n 
D 2 253 LEU 253 423 423 LEU LEU D . n 
D 2 254 LEU 254 424 424 LEU LEU D . n 
D 2 255 ASN 255 425 425 ASN ASN D . n 
D 2 256 PRO 256 426 426 PRO PRO D . n 
D 2 257 PRO 257 427 427 PRO PRO D . n 
D 2 258 GLU 258 428 428 GLU GLU D . n 
D 2 259 THR 259 429 429 THR THR D . n 
D 2 260 LEU 260 430 430 LEU LEU D . n 
D 2 261 ASN 261 431 431 ASN ASN D . n 
D 2 262 VAL 262 432 432 VAL VAL D . n 
D 2 263 HIS 263 433 ?   ?   ?   D . n 
D 2 264 HIS 264 434 ?   ?   ?   D . n 
D 2 265 HIS 265 435 ?   ?   ?   D . n 
D 2 266 HIS 266 436 ?   ?   ?   D . n 
D 2 267 HIS 267 437 ?   ?   ?   D . n 
D 2 268 HIS 268 438 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        UUS 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   UUS 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 UUS 1   301 703 UUS DRG A . 
F 3 UUS 1   701 701 UUS DRG B . 
G 3 UUS 1   501 501 UUS DRG C . 
H 3 UUS 1   502 702 UUS DRG C . 
I 3 UUS 1   701 701 UUS DRG D . 
J 4 HOH 1   401 566 HOH HOH A . 
J 4 HOH 2   402 408 HOH HOH A . 
J 4 HOH 3   403 401 HOH HOH A . 
J 4 HOH 4   404 440 HOH HOH A . 
J 4 HOH 5   405 474 HOH HOH A . 
J 4 HOH 6   406 479 HOH HOH A . 
J 4 HOH 7   407 467 HOH HOH A . 
J 4 HOH 8   408 421 HOH HOH A . 
J 4 HOH 9   409 428 HOH HOH A . 
J 4 HOH 10  410 451 HOH HOH A . 
J 4 HOH 11  411 475 HOH HOH A . 
J 4 HOH 12  412 436 HOH HOH A . 
J 4 HOH 13  413 465 HOH HOH A . 
J 4 HOH 14  414 432 HOH HOH A . 
J 4 HOH 15  415 480 HOH HOH A . 
J 4 HOH 16  416 515 HOH HOH A . 
J 4 HOH 17  417 452 HOH HOH A . 
J 4 HOH 18  418 425 HOH HOH A . 
J 4 HOH 19  419 497 HOH HOH A . 
J 4 HOH 20  420 486 HOH HOH A . 
J 4 HOH 21  421 444 HOH HOH A . 
J 4 HOH 22  422 430 HOH HOH A . 
J 4 HOH 23  423 506 HOH HOH A . 
J 4 HOH 24  424 580 HOH HOH A . 
J 4 HOH 25  425 456 HOH HOH A . 
J 4 HOH 26  426 520 HOH HOH A . 
J 4 HOH 27  427 448 HOH HOH A . 
J 4 HOH 28  428 402 HOH HOH A . 
J 4 HOH 29  429 470 HOH HOH A . 
J 4 HOH 30  430 522 HOH HOH A . 
J 4 HOH 31  431 461 HOH HOH A . 
J 4 HOH 32  432 525 HOH HOH A . 
J 4 HOH 33  433 427 HOH HOH A . 
J 4 HOH 34  434 504 HOH HOH A . 
J 4 HOH 35  435 483 HOH HOH A . 
J 4 HOH 36  436 457 HOH HOH A . 
J 4 HOH 37  437 477 HOH HOH A . 
J 4 HOH 38  438 464 HOH HOH A . 
J 4 HOH 39  439 438 HOH HOH A . 
J 4 HOH 40  440 462 HOH HOH A . 
J 4 HOH 41  441 517 HOH HOH A . 
J 4 HOH 42  442 545 HOH HOH A . 
J 4 HOH 43  443 510 HOH HOH A . 
J 4 HOH 44  444 491 HOH HOH A . 
J 4 HOH 45  445 423 HOH HOH A . 
J 4 HOH 46  446 511 HOH HOH A . 
J 4 HOH 47  447 494 HOH HOH A . 
J 4 HOH 48  448 493 HOH HOH A . 
J 4 HOH 49  449 420 HOH HOH A . 
J 4 HOH 50  450 554 HOH HOH A . 
J 4 HOH 51  451 503 HOH HOH A . 
J 4 HOH 52  452 484 HOH HOH A . 
J 4 HOH 53  453 509 HOH HOH A . 
J 4 HOH 54  454 482 HOH HOH A . 
J 4 HOH 55  455 478 HOH HOH A . 
J 4 HOH 56  456 523 HOH HOH A . 
J 4 HOH 57  457 410 HOH HOH A . 
J 4 HOH 58  458 485 HOH HOH A . 
J 4 HOH 59  459 544 HOH HOH A . 
J 4 HOH 60  460 490 HOH HOH A . 
J 4 HOH 61  461 468 HOH HOH A . 
J 4 HOH 62  462 429 HOH HOH A . 
J 4 HOH 63  463 500 HOH HOH A . 
J 4 HOH 64  464 512 HOH HOH A . 
J 4 HOH 65  465 502 HOH HOH A . 
J 4 HOH 66  466 556 HOH HOH A . 
J 4 HOH 67  467 455 HOH HOH A . 
J 4 HOH 68  468 487 HOH HOH A . 
J 4 HOH 69  469 524 HOH HOH A . 
J 4 HOH 70  470 526 HOH HOH A . 
J 4 HOH 71  471 435 HOH HOH A . 
J 4 HOH 72  472 532 HOH HOH A . 
J 4 HOH 73  473 447 HOH HOH A . 
J 4 HOH 74  474 533 HOH HOH A . 
J 4 HOH 75  475 419 HOH HOH A . 
J 4 HOH 76  476 564 HOH HOH A . 
J 4 HOH 77  477 466 HOH HOH A . 
J 4 HOH 78  478 527 HOH HOH A . 
J 4 HOH 79  479 558 HOH HOH A . 
J 4 HOH 80  480 550 HOH HOH A . 
J 4 HOH 81  481 573 HOH HOH A . 
J 4 HOH 82  482 529 HOH HOH A . 
J 4 HOH 83  483 549 HOH HOH A . 
J 4 HOH 84  484 552 HOH HOH A . 
J 4 HOH 85  485 570 HOH HOH A . 
J 4 HOH 86  486 535 HOH HOH A . 
J 4 HOH 87  487 551 HOH HOH A . 
J 4 HOH 88  488 443 HOH HOH A . 
J 4 HOH 89  489 559 HOH HOH A . 
J 4 HOH 90  490 488 HOH HOH A . 
J 4 HOH 91  491 571 HOH HOH A . 
J 4 HOH 92  492 542 HOH HOH A . 
J 4 HOH 93  493 585 HOH HOH A . 
J 4 HOH 94  494 534 HOH HOH A . 
J 4 HOH 95  495 569 HOH HOH A . 
J 4 HOH 96  496 514 HOH HOH A . 
J 4 HOH 97  497 508 HOH HOH A . 
J 4 HOH 98  498 546 HOH HOH A . 
J 4 HOH 99  499 574 HOH HOH A . 
J 4 HOH 100 500 653 HOH HOH A . 
J 4 HOH 101 501 582 HOH HOH A . 
J 4 HOH 102 502 577 HOH HOH A . 
J 4 HOH 103 503 586 HOH HOH A . 
J 4 HOH 104 504 8   HOH HOH A . 
J 4 HOH 105 505 647 HOH HOH A . 
J 4 HOH 106 506 597 HOH HOH A . 
K 4 HOH 1   801 502 HOH HOH B . 
K 4 HOH 2   802 551 HOH HOH B . 
K 4 HOH 3   803 507 HOH HOH B . 
K 4 HOH 4   804 34  HOH HOH B . 
K 4 HOH 5   805 537 HOH HOH B . 
K 4 HOH 6   806 613 HOH HOH B . 
K 4 HOH 7   807 506 HOH HOH B . 
K 4 HOH 8   808 523 HOH HOH B . 
K 4 HOH 9   809 563 HOH HOH B . 
K 4 HOH 10  810 548 HOH HOH B . 
K 4 HOH 11  811 521 HOH HOH B . 
K 4 HOH 12  812 508 HOH HOH B . 
K 4 HOH 13  813 568 HOH HOH B . 
K 4 HOH 14  814 532 HOH HOH B . 
K 4 HOH 15  815 459 HOH HOH B . 
K 4 HOH 16  816 556 HOH HOH B . 
K 4 HOH 17  817 570 HOH HOH B . 
K 4 HOH 18  818 574 HOH HOH B . 
K 4 HOH 19  819 583 HOH HOH B . 
K 4 HOH 20  820 562 HOH HOH B . 
K 4 HOH 21  821 571 HOH HOH B . 
K 4 HOH 22  822 543 HOH HOH B . 
K 4 HOH 23  823 572 HOH HOH B . 
K 4 HOH 24  824 584 HOH HOH B . 
K 4 HOH 25  825 524 HOH HOH B . 
K 4 HOH 26  826 588 HOH HOH B . 
K 4 HOH 27  827 575 HOH HOH B . 
K 4 HOH 28  828 510 HOH HOH B . 
K 4 HOH 29  829 522 HOH HOH B . 
K 4 HOH 30  830 545 HOH HOH B . 
K 4 HOH 31  831 644 HOH HOH B . 
K 4 HOH 32  832 659 HOH HOH B . 
K 4 HOH 33  833 531 HOH HOH B . 
K 4 HOH 34  834 564 HOH HOH B . 
K 4 HOH 35  835 538 HOH HOH B . 
K 4 HOH 36  836 555 HOH HOH B . 
K 4 HOH 37  837 566 HOH HOH B . 
K 4 HOH 38  838 594 HOH HOH B . 
K 4 HOH 39  839 560 HOH HOH B . 
K 4 HOH 40  840 607 HOH HOH B . 
K 4 HOH 41  841 622 HOH HOH B . 
K 4 HOH 42  842 617 HOH HOH B . 
K 4 HOH 43  843 585 HOH HOH B . 
K 4 HOH 44  844 558 HOH HOH B . 
K 4 HOH 45  845 604 HOH HOH B . 
K 4 HOH 46  846 557 HOH HOH B . 
K 4 HOH 47  847 529 HOH HOH B . 
K 4 HOH 48  848 550 HOH HOH B . 
K 4 HOH 49  849 525 HOH HOH B . 
K 4 HOH 50  850 535 HOH HOH B . 
K 4 HOH 51  851 511 HOH HOH B . 
K 4 HOH 52  852 593 HOH HOH B . 
K 4 HOH 53  853 520 HOH HOH B . 
K 4 HOH 54  854 546 HOH HOH B . 
K 4 HOH 55  855 615 HOH HOH B . 
K 4 HOH 56  856 624 HOH HOH B . 
K 4 HOH 57  857 609 HOH HOH B . 
K 4 HOH 58  858 595 HOH HOH B . 
K 4 HOH 59  859 614 HOH HOH B . 
K 4 HOH 60  860 581 HOH HOH B . 
K 4 HOH 61  861 526 HOH HOH B . 
K 4 HOH 62  862 582 HOH HOH B . 
K 4 HOH 63  863 637 HOH HOH B . 
K 4 HOH 64  864 612 HOH HOH B . 
K 4 HOH 65  865 544 HOH HOH B . 
K 4 HOH 66  866 589 HOH HOH B . 
K 4 HOH 67  867 528 HOH HOH B . 
K 4 HOH 68  868 596 HOH HOH B . 
K 4 HOH 69  869 639 HOH HOH B . 
K 4 HOH 70  870 577 HOH HOH B . 
K 4 HOH 71  871 561 HOH HOH B . 
K 4 HOH 72  872 592 HOH HOH B . 
K 4 HOH 73  873 638 HOH HOH B . 
K 4 HOH 74  874 598 HOH HOH B . 
K 4 HOH 75  875 630 HOH HOH B . 
K 4 HOH 76  876 633 HOH HOH B . 
K 4 HOH 77  877 619 HOH HOH B . 
K 4 HOH 78  878 559 HOH HOH B . 
K 4 HOH 79  879 554 HOH HOH B . 
K 4 HOH 80  880 643 HOH HOH B . 
K 4 HOH 81  881 605 HOH HOH B . 
K 4 HOH 82  882 628 HOH HOH B . 
K 4 HOH 83  883 641 HOH HOH B . 
K 4 HOH 84  884 587 HOH HOH B . 
K 4 HOH 85  885 629 HOH HOH B . 
K 4 HOH 86  886 621 HOH HOH B . 
K 4 HOH 87  887 586 HOH HOH B . 
K 4 HOH 88  888 650 HOH HOH B . 
K 4 HOH 89  889 620 HOH HOH B . 
K 4 HOH 90  890 666 HOH HOH B . 
K 4 HOH 91  891 625 HOH HOH B . 
K 4 HOH 92  892 640 HOH HOH B . 
K 4 HOH 93  893 590 HOH HOH B . 
K 4 HOH 94  894 665 HOH HOH B . 
K 4 HOH 95  895 631 HOH HOH B . 
K 4 HOH 96  896 618 HOH HOH B . 
K 4 HOH 97  897 636 HOH HOH B . 
K 4 HOH 98  898 657 HOH HOH B . 
K 4 HOH 99  899 669 HOH HOH B . 
K 4 HOH 100 900 648 HOH HOH B . 
K 4 HOH 101 901 663 HOH HOH B . 
K 4 HOH 102 902 651 HOH HOH B . 
K 4 HOH 103 903 661 HOH HOH B . 
K 4 HOH 104 904 674 HOH HOH B . 
K 4 HOH 105 905 635 HOH HOH B . 
K 4 HOH 106 906 675 HOH HOH B . 
K 4 HOH 107 907 672 HOH HOH B . 
K 4 HOH 108 908 676 HOH HOH B . 
K 4 HOH 109 909 9   HOH HOH B . 
K 4 HOH 110 910 680 HOH HOH B . 
K 4 HOH 111 911 679 HOH HOH B . 
K 4 HOH 112 912 681 HOH HOH B . 
K 4 HOH 113 913 684 HOH HOH B . 
L 4 HOH 1   601 417 HOH HOH C . 
L 4 HOH 2   602 432 HOH HOH C . 
L 4 HOH 3   603 404 HOH HOH C . 
L 4 HOH 4   604 419 HOH HOH C . 
L 4 HOH 5   605 407 HOH HOH C . 
L 4 HOH 6   606 437 HOH HOH C . 
L 4 HOH 7   607 425 HOH HOH C . 
L 4 HOH 8   608 406 HOH HOH C . 
L 4 HOH 9   609 410 HOH HOH C . 
L 4 HOH 10  610 438 HOH HOH C . 
L 4 HOH 11  611 422 HOH HOH C . 
L 4 HOH 12  612 439 HOH HOH C . 
L 4 HOH 13  613 412 HOH HOH C . 
L 4 HOH 14  614 616 HOH HOH C . 
L 4 HOH 15  615 430 HOH HOH C . 
L 4 HOH 16  616 424 HOH HOH C . 
L 4 HOH 17  617 433 HOH HOH C . 
L 4 HOH 18  618 465 HOH HOH C . 
L 4 HOH 19  619 434 HOH HOH C . 
L 4 HOH 20  620 22  HOH HOH C . 
L 4 HOH 21  621 415 HOH HOH C . 
L 4 HOH 22  622 448 HOH HOH C . 
L 4 HOH 23  623 526 HOH HOH C . 
L 4 HOH 24  624 452 HOH HOH C . 
L 4 HOH 25  625 403 HOH HOH C . 
L 4 HOH 26  626 445 HOH HOH C . 
L 4 HOH 27  627 428 HOH HOH C . 
L 4 HOH 28  628 426 HOH HOH C . 
L 4 HOH 29  629 427 HOH HOH C . 
L 4 HOH 30  630 453 HOH HOH C . 
L 4 HOH 31  631 471 HOH HOH C . 
L 4 HOH 32  632 401 HOH HOH C . 
L 4 HOH 33  633 23  HOH HOH C . 
L 4 HOH 34  634 468 HOH HOH C . 
L 4 HOH 35  635 451 HOH HOH C . 
L 4 HOH 36  636 429 HOH HOH C . 
L 4 HOH 37  637 7   HOH HOH C . 
L 4 HOH 38  638 454 HOH HOH C . 
L 4 HOH 39  639 456 HOH HOH C . 
L 4 HOH 40  640 38  HOH HOH C . 
L 4 HOH 41  641 455 HOH HOH C . 
L 4 HOH 42  642 447 HOH HOH C . 
L 4 HOH 43  643 459 HOH HOH C . 
L 4 HOH 44  644 442 HOH HOH C . 
L 4 HOH 45  645 37  HOH HOH C . 
L 4 HOH 46  646 36  HOH HOH C . 
L 4 HOH 47  647 26  HOH HOH C . 
L 4 HOH 48  648 469 HOH HOH C . 
L 4 HOH 49  649 473 HOH HOH C . 
L 4 HOH 50  650 475 HOH HOH C . 
L 4 HOH 51  651 477 HOH HOH C . 
M 4 HOH 1   801 519 HOH HOH D . 
M 4 HOH 2   802 505 HOH HOH D . 
M 4 HOH 3   803 501 HOH HOH D . 
M 4 HOH 4   804 532 HOH HOH D . 
M 4 HOH 5   805 555 HOH HOH D . 
M 4 HOH 6   806 522 HOH HOH D . 
M 4 HOH 7   807 435 HOH HOH D . 
M 4 HOH 8   808 506 HOH HOH D . 
M 4 HOH 9   809 512 HOH HOH D . 
M 4 HOH 10  810 509 HOH HOH D . 
M 4 HOH 11  811 547 HOH HOH D . 
M 4 HOH 12  812 533 HOH HOH D . 
M 4 HOH 13  813 504 HOH HOH D . 
M 4 HOH 14  814 554 HOH HOH D . 
M 4 HOH 15  815 524 HOH HOH D . 
M 4 HOH 16  816 521 HOH HOH D . 
M 4 HOH 17  817 511 HOH HOH D . 
M 4 HOH 18  818 543 HOH HOH D . 
M 4 HOH 19  819 537 HOH HOH D . 
M 4 HOH 20  820 507 HOH HOH D . 
M 4 HOH 21  821 523 HOH HOH D . 
M 4 HOH 22  822 520 HOH HOH D . 
M 4 HOH 23  823 515 HOH HOH D . 
M 4 HOH 24  824 529 HOH HOH D . 
M 4 HOH 25  825 538 HOH HOH D . 
M 4 HOH 26  826 536 HOH HOH D . 
M 4 HOH 27  827 540 HOH HOH D . 
M 4 HOH 28  828 566 HOH HOH D . 
M 4 HOH 29  829 563 HOH HOH D . 
M 4 HOH 30  830 552 HOH HOH D . 
M 4 HOH 31  831 562 HOH HOH D . 
M 4 HOH 32  832 541 HOH HOH D . 
M 4 HOH 33  833 558 HOH HOH D . 
M 4 HOH 34  834 561 HOH HOH D . 
M 4 HOH 35  835 568 HOH HOH D . 
M 4 HOH 36  836 542 HOH HOH D . 
M 4 HOH 37  837 564 HOH HOH D . 
M 4 HOH 38  838 572 HOH HOH D . 
M 4 HOH 39  839 551 HOH HOH D . 
M 4 HOH 40  840 579 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ESN 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.176 
_cell.length_a_esd                 ? 
_cell.length_b                     134.163 
_cell.length_b_esd                 ? 
_cell.length_c                     147.945 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ESN 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ESN 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.82 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.44 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'Protein at 10 mg/ml. 0.6 to 0.8 M KCl, 0.9 to 1.2 M (NH4)2SO4, and 100 mM HEPES pH 7.0' 
_exptl_crystal_grow.pdbx_pH_range   7-7.5 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.89842 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.89842 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9ESN 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.38 
_reflns.d_resolution_low                               147.95 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     56963 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           94.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.205 
_reflns.pdbx_Rpim_I_all                                0.076 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.19 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
10.1 147.95 ? 36.2 ? ? ? ? 915  ? ? ? ? ? ? ? ? ? ? ? 12.2 ? ? ? 0.044 0.016 ? 1 1 1     ? ? 99.9 ? 0.041 ? ? ? ? ? ? ? ? ? 
2.38 2.45   ? 0.9  ? ? ? ? 4829 ? ? ? ? ? ? ? ? ? ? ? 13.4 ? ? ? 2.914 1.105 ? 2 1 0.482 ? ? 100  ? 2.695 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -1.364 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            1.350 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            0.014 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               65.273 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.961 
_refine.correlation_coeff_Fo_to_Fc_free          0.950 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ESN 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.393 
_refine.ls_d_res_low                             99.582 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     55159 
_refine.ls_number_reflns_R_free                  2799 
_refine.ls_number_reflns_R_work                  52360 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    93.545 
_refine.ls_percent_reflns_R_free                 5.074 
_refine.ls_R_factor_all                          0.209 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2134 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2093 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.414 
_refine.pdbx_overall_ESU_R_Free                  0.225 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.393 
_refine_hist.d_res_low                        99.582 
_refine_hist.number_atoms_solvent             310 
_refine_hist.number_atoms_total               9358 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8993 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         55 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  9290  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.615  1.846  12624 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 5.804  5.000  1119  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 21.135 5.000  44    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.259 10.000 1615  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.796 10.000 401   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.100  0.200  1426  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  6963  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.217  0.200  4425  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.314  0.200  6341  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.144  0.200  408   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.313  0.200  64    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.157  0.200  12    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 4.158  6.334  4482  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.488  11.393 5599  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.688  6.679  4808  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 8.649  12.105 7025  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 11.728 71.672 14214 ? r_lrange_it                    ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.393  2.456  4236 . 153 3369 83.1445  . 1.226 . . 1.229 . . . . . 1.293 . 20 . 0.748 0.701 1.166 
'X-RAY DIFFRACTION' 2.456  2.523  4210 . 236 3974 100.0000 . 0.573 . . 0.573 . . . . . 0.576 . 20 . 0.835 0.847 0.571 
'X-RAY DIFFRACTION' 2.523  2.596  4096 . 221 3875 100.0000 . 0.338 . . 0.337 . . . . . 0.343 . 20 . 0.936 0.922 0.366 
'X-RAY DIFFRACTION' 2.596  2.676  3949 . 143 2740 73.0058  . 0.292 . . 0.293 . . . . . 0.297 . 20 . 0.946 0.949 0.271 
'X-RAY DIFFRACTION' 2.676  2.763  3855 . 167 3199 87.3152  . 0.268 . . 0.270 . . . . . 0.267 . 20 . 0.954 0.962 0.236 
'X-RAY DIFFRACTION' 2.763  2.860  3747 . 177 3570 100.0000 . 0.259 . . 0.259 . . . . . 0.254 . 20 . 0.957 0.962 0.253 
'X-RAY DIFFRACTION' 2.860  2.968  3587 . 202 3385 100.0000 . 0.250 . . 0.251 . . . . . 0.242 . 20 . 0.960 0.962 0.245 
'X-RAY DIFFRACTION' 2.968  3.089  3471 . 182 3289 100.0000 . 0.237 . . 0.238 . . . . . 0.229 . 20 . 0.967 0.972 0.224 
'X-RAY DIFFRACTION' 3.089  3.227  3356 . 166 3190 100.0000 . 0.227 . . 0.229 . . . . . 0.218 . 20 . 0.970 0.979 0.197 
'X-RAY DIFFRACTION' 3.227  3.384  3188 . 152 3036 100.0000 . 0.217 . . 0.216 . . . . . 0.206 . 20 . 0.974 0.967 0.241 
'X-RAY DIFFRACTION' 3.384  3.567  3033 . 131 2320 80.8111  . 0.192 . . 0.191 . . . . . 0.185 . 20 . 0.981 0.985 0.194 
'X-RAY DIFFRACTION' 3.567  3.783  2877 . 136 2295 84.4977  . 0.183 . . 0.184 . . . . . 0.178 . 20 . 0.981 0.984 0.174 
'X-RAY DIFFRACTION' 3.783  4.043  2715 . 90  2139 82.0994  . 0.166 . . 0.166 . . . . . 0.160 . 20 . 0.984 0.983 0.172 
'X-RAY DIFFRACTION' 4.043  4.367  2562 . 140 2422 100.0000 . 0.150 . . 0.149 . . . . . 0.144 . 20 . 0.988 0.989 0.153 
'X-RAY DIFFRACTION' 4.367  4.783  2344 . 123 2221 100.0000 . 0.151 . . 0.151 . . . . . 0.146 . 20 . 0.986 0.985 0.158 
'X-RAY DIFFRACTION' 4.783  5.346  2138 . 95  2043 100.0000 . 0.164 . . 0.163 . . . . . 0.159 . 20 . 0.985 0.981 0.176 
'X-RAY DIFFRACTION' 5.346  6.170  1903 . 100 1803 100.0000 . 0.194 . . 0.193 . . . . . 0.187 . 20 . 0.983 0.982 0.198 
'X-RAY DIFFRACTION' 6.170  7.549  1615 . 91  1524 100.0000 . 0.200 . . 0.198 . . . . . 0.194 . 20 . 0.982 0.970 0.228 
'X-RAY DIFFRACTION' 7.549  10.646 1294 . 57  1237 100.0000 . 0.139 . . 0.139 . . . . . 0.143 . 20 . 0.989 0.991 0.138 
'X-RAY DIFFRACTION' 10.646 99.582 767  . 37  729  99.8696  . 0.213 . . 0.209 . . . . . 0.244 . 20 . 0.970 0.909 0.313 
# 
_struct.entry_id                     9ESN 
_struct.title                        'CDK2-cyclin A in complex with FragLite 28' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ESN 
_struct_keywords.text            'cyclin-dependent kinase, FragLite, CDK2, cyclin A, Fragment, CELL CYCLE' 
_struct_keywords.pdbx_keywords   'CELL CYCLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CDK2_HUMAN  P24941 ? 1 
;MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF
EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT
HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
;
1   
2 UNP CCNA2_BOVIN P30274 ? 2 
;VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRG
KLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLAFDLAAPTINQFLTQYFLHQQPANCKVES
LAMFLGELSLIDADPYLKYLPSVIAAAAFHLALYTVTGQSWPESLVQKTGYTLETLKPCLLDLHQTYLRAPQHAQQSIRE
KYKNSKYHGVSLLNPPETLNV
;
170 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ESN A 5 ? 302 ? P24941 1   ? 298 ? 1   298 
2 2 9ESN B 2 ? 262 ? P30274 170 ? 430 ? 172 432 
3 1 9ESN C 5 ? 302 ? P24941 1   ? 298 ? 1   298 
4 2 9ESN D 2 ? 262 ? P30274 170 ? 430 ? 172 432 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9ESN GLY A 1   ? UNP P24941 ? ? 'expression tag' -3  1  
1 9ESN PRO A 2   ? UNP P24941 ? ? 'expression tag' -2  2  
1 9ESN GLY A 3   ? UNP P24941 ? ? 'expression tag' -1  3  
1 9ESN SER A 4   ? UNP P24941 ? ? 'expression tag' 0   4  
2 9ESN GLY B 1   ? UNP P30274 ? ? 'expression tag' 171 5  
2 9ESN HIS B 263 ? UNP P30274 ? ? 'expression tag' 433 6  
2 9ESN HIS B 264 ? UNP P30274 ? ? 'expression tag' 434 7  
2 9ESN HIS B 265 ? UNP P30274 ? ? 'expression tag' 435 8  
2 9ESN HIS B 266 ? UNP P30274 ? ? 'expression tag' 436 9  
2 9ESN HIS B 267 ? UNP P30274 ? ? 'expression tag' 437 10 
2 9ESN HIS B 268 ? UNP P30274 ? ? 'expression tag' 438 11 
3 9ESN GLY C 1   ? UNP P24941 ? ? 'expression tag' -3  12 
3 9ESN PRO C 2   ? UNP P24941 ? ? 'expression tag' -2  13 
3 9ESN GLY C 3   ? UNP P24941 ? ? 'expression tag' -1  14 
3 9ESN SER C 4   ? UNP P24941 ? ? 'expression tag' 0   15 
4 9ESN GLY D 1   ? UNP P30274 ? ? 'expression tag' 171 16 
4 9ESN HIS D 263 ? UNP P30274 ? ? 'expression tag' 433 17 
4 9ESN HIS D 264 ? UNP P30274 ? ? 'expression tag' 434 18 
4 9ESN HIS D 265 ? UNP P30274 ? ? 'expression tag' 435 19 
4 9ESN HIS D 266 ? UNP P30274 ? ? 'expression tag' 436 20 
4 9ESN HIS D 267 ? UNP P30274 ? ? 'expression tag' 437 21 
4 9ESN HIS D 268 ? UNP P30274 ? ? 'expression tag' 438 22 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3600  ? 
1 MORE         -14   ? 
1 'SSA (A^2)'  23170 ? 
2 'ABSA (A^2)' 3750  ? 
2 MORE         -15   ? 
2 'SSA (A^2)'  23110 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,J,K   
2 1 C,D,G,H,I,L,M 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 4   ? GLU A 6   ? SER A 0   GLU A 2   5 ? 3  
HELX_P HELX_P2  AA2 PRO A 49  ? LEU A 62  ? PRO A 45  LEU A 58  1 ? 14 
HELX_P HELX_P3  AA3 LEU A 91  ? SER A 98  ? LEU A 87  SER A 94  1 ? 8  
HELX_P HELX_P4  AA4 PRO A 104 ? HIS A 125 ? PRO A 100 HIS A 121 1 ? 22 
HELX_P HELX_P5  AA5 LYS A 133 ? GLN A 135 ? LYS A 129 GLN A 131 5 ? 3  
HELX_P HELX_P6  AA6 THR A 169 ? ARG A 173 ? THR A 165 ARG A 169 5 ? 5  
HELX_P HELX_P7  AA7 ALA A 174 ? LEU A 179 ? ALA A 170 LEU A 175 1 ? 6  
HELX_P HELX_P8  AA8 THR A 186 ? ARG A 203 ? THR A 182 ARG A 199 1 ? 18 
HELX_P HELX_P9  AA9 SER A 211 ? GLY A 224 ? SER A 207 GLY A 220 1 ? 14 
HELX_P HELX_P10 AB1 GLY A 233 ? MET A 237 ? GLY A 229 MET A 233 5 ? 5  
HELX_P HELX_P11 AB2 ASP A 260 ? LEU A 271 ? ASP A 256 LEU A 267 1 ? 12 
HELX_P HELX_P12 AB3 SER A 280 ? LEU A 285 ? SER A 276 LEU A 281 1 ? 6  
HELX_P HELX_P13 AB4 ALA A 286 ? GLN A 291 ? ALA A 282 GLN A 287 5 ? 6  
HELX_P HELX_P14 AB5 GLY B 1   ? VAL B 5   ? GLY B 171 VAL B 175 5 ? 5  
HELX_P HELX_P15 AB6 TYR B 8   ? CYS B 23  ? TYR B 178 CYS B 193 1 ? 16 
HELX_P HELX_P16 AB7 THR B 37  ? TYR B 55  ? THR B 207 TYR B 225 1 ? 19 
HELX_P HELX_P17 AB8 GLN B 58  ? MET B 76  ? GLN B 228 MET B 246 1 ? 19 
HELX_P HELX_P18 AB9 LEU B 79  ? GLY B 81  ? LEU B 249 GLY B 251 5 ? 3  
HELX_P HELX_P19 AC1 LYS B 82  ? GLU B 99  ? LYS B 252 GLU B 269 1 ? 18 
HELX_P HELX_P20 AC2 GLU B 104 ? THR B 112 ? GLU B 274 THR B 282 1 ? 9  
HELX_P HELX_P21 AC3 THR B 117 ? ALA B 133 ? THR B 287 ALA B 303 1 ? 17 
HELX_P HELX_P22 AC4 THR B 140 ? LEU B 150 ? THR B 310 LEU B 320 1 ? 11 
HELX_P HELX_P23 AC5 ASN B 156 ? ASP B 173 ? ASN B 326 ASP B 343 1 ? 18 
HELX_P HELX_P24 AC6 ASP B 173 ? LEU B 178 ? ASP B 343 LEU B 348 1 ? 6  
HELX_P HELX_P25 AC7 LEU B 181 ? GLY B 199 ? LEU B 351 GLY B 369 1 ? 19 
HELX_P HELX_P26 AC8 PRO B 203 ? GLY B 211 ? PRO B 373 GLY B 381 1 ? 9  
HELX_P HELX_P27 AC9 THR B 213 ? ARG B 230 ? THR B 383 ARG B 400 1 ? 18 
HELX_P HELX_P28 AD1 GLN B 237 ? TYR B 243 ? GLN B 407 TYR B 413 1 ? 7  
HELX_P HELX_P29 AD2 LYS B 244 ? HIS B 249 ? LYS B 414 HIS B 419 5 ? 6  
HELX_P HELX_P30 AD3 GLY B 250 ? LEU B 254 ? GLY B 420 LEU B 424 5 ? 5  
HELX_P HELX_P31 AD4 PRO C 49  ? LEU C 62  ? PRO C 45  LEU C 58  1 ? 14 
HELX_P HELX_P32 AD5 LEU C 91  ? SER C 98  ? LEU C 87  SER C 94  1 ? 8  
HELX_P HELX_P33 AD6 PRO C 104 ? HIS C 125 ? PRO C 100 HIS C 121 1 ? 22 
HELX_P HELX_P34 AD7 LYS C 133 ? GLN C 135 ? LYS C 129 GLN C 131 5 ? 3  
HELX_P HELX_P35 AD8 THR C 169 ? ARG C 173 ? THR C 165 ARG C 169 5 ? 5  
HELX_P HELX_P36 AD9 ALA C 174 ? LEU C 179 ? ALA C 170 LEU C 175 1 ? 6  
HELX_P HELX_P37 AE1 THR C 186 ? ARG C 203 ? THR C 182 ARG C 199 1 ? 18 
HELX_P HELX_P38 AE2 SER C 211 ? GLY C 224 ? SER C 207 GLY C 220 1 ? 14 
HELX_P HELX_P39 AE3 GLY C 233 ? MET C 237 ? GLY C 229 MET C 233 5 ? 5  
HELX_P HELX_P40 AE4 ASP C 251 ? VAL C 256 ? ASP C 247 VAL C 252 1 ? 6  
HELX_P HELX_P41 AE5 ASP C 260 ? LEU C 271 ? ASP C 256 LEU C 267 1 ? 12 
HELX_P HELX_P42 AE6 SER C 280 ? HIS C 287 ? SER C 276 HIS C 283 1 ? 8  
HELX_P HELX_P43 AE7 PRO C 288 ? GLN C 291 ? PRO C 284 GLN C 287 5 ? 4  
HELX_P HELX_P44 AE8 GLY D 1   ? VAL D 5   ? GLY D 171 VAL D 175 5 ? 5  
HELX_P HELX_P45 AE9 TYR D 8   ? CYS D 23  ? TYR D 178 CYS D 193 1 ? 16 
HELX_P HELX_P46 AF1 THR D 37  ? TYR D 55  ? THR D 207 TYR D 225 1 ? 19 
HELX_P HELX_P47 AF2 GLN D 58  ? SER D 74  ? GLN D 228 SER D 244 1 ? 17 
HELX_P HELX_P48 AF3 LEU D 79  ? GLY D 81  ? LEU D 249 GLY D 251 5 ? 3  
HELX_P HELX_P49 AF4 LYS D 82  ? GLU D 99  ? LYS D 252 GLU D 269 1 ? 18 
HELX_P HELX_P50 AF5 GLU D 104 ? ILE D 111 ? GLU D 274 ILE D 281 1 ? 8  
HELX_P HELX_P51 AF6 THR D 117 ? LEU D 132 ? THR D 287 LEU D 302 1 ? 16 
HELX_P HELX_P52 AF7 THR D 140 ? PHE D 149 ? THR D 310 PHE D 319 1 ? 10 
HELX_P HELX_P53 AF8 LEU D 150 ? GLN D 152 ? LEU D 320 GLN D 322 5 ? 3  
HELX_P HELX_P54 AF9 ASN D 156 ? LEU D 171 ? ASN D 326 LEU D 341 1 ? 16 
HELX_P HELX_P55 AG1 ASP D 173 ? LEU D 178 ? ASP D 343 LEU D 348 1 ? 6  
HELX_P HELX_P56 AG2 LEU D 181 ? GLY D 199 ? LEU D 351 GLY D 369 1 ? 19 
HELX_P HELX_P57 AG3 PRO D 203 ? GLY D 211 ? PRO D 373 GLY D 381 1 ? 9  
HELX_P HELX_P58 AG4 LEU D 217 ? ALA D 231 ? LEU D 387 ALA D 401 1 ? 15 
HELX_P HELX_P59 AG5 PRO D 232 ? HIS D 234 ? PRO D 402 HIS D 404 5 ? 3  
HELX_P HELX_P60 AG6 GLN D 237 ? TYR D 243 ? GLN D 407 TYR D 413 1 ? 7  
HELX_P HELX_P61 AG7 ASN D 245 ? HIS D 249 ? ASN D 415 HIS D 419 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A TYR 163 C ? ? ? 1_555 A TPO 164 N ? ? A TYR 159 A TPO 160 1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale2 covale both ? A TPO 164 C ? ? ? 1_555 A HIS 165 N ? ? A TPO 160 A HIS 161 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale3 covale both ? C TYR 163 C ? ? ? 1_555 C TPO 164 N ? ? C TYR 159 C TPO 160 1_555 ? ? ? ? ? ? ? 1.349 ? ? 
covale4 covale both ? C TPO 164 C ? ? ? 1_555 C HIS 165 N ? ? C TPO 160 C HIS 161 1_555 ? ? ? ? ? ? ? 1.341 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 TPO A 164 ? . . . . TPO A 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
2 TPO C 164 ? . . . . TPO C 160 ? 1_555 . . . . . . . THR 1 TPO Phosphorylation 'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 VAL 158 A . ? VAL 154 A PRO 159 A ? PRO 155 A 1 -8.45 
2 GLN 153 B . ? GLN 323 B PRO 154 B ? PRO 324 B 1 -6.32 
3 ASP 175 B . ? ASP 345 B PRO 176 B ? PRO 346 B 1 14.09 
4 VAL 158 C . ? VAL 154 C PRO 159 C ? PRO 155 C 1 -1.62 
5 GLN 153 D . ? GLN 323 D PRO 154 D ? PRO 324 D 1 15.18 
6 ASP 175 D . ? ASP 345 D PRO 176 D ? PRO 346 D 1 8.56  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 8   ? GLU A 16  ? PHE A 4   GLU A 12  
AA1 2 VAL A 21  ? ASN A 27  ? VAL A 17  ASN A 23  
AA1 3 VAL A 33  ? ARG A 40  ? VAL A 29  ARG A 36  
AA1 4 LYS A 79  ? GLU A 85  ? LYS A 75  GLU A 81  
AA1 5 LEU A 70  ? HIS A 75  ? LEU A 66  HIS A 71  
AA2 1 GLN A 89  ? ASP A 90  ? GLN A 85  ASP A 86  
AA2 2 LEU A 137 ? ILE A 139 ? LEU A 133 ILE A 135 
AA2 3 ILE A 145 ? LEU A 147 ? ILE A 141 LEU A 143 
AA3 1 VAL A 127 ? LEU A 128 ? VAL A 123 LEU A 124 
AA3 2 ARG A 154 ? ALA A 155 ? ARG A 150 ALA A 151 
AA4 1 PHE C 8   ? GLU C 16  ? PHE C 4   GLU C 12  
AA4 2 VAL C 21  ? ASN C 27  ? VAL C 17  ASN C 23  
AA4 3 VAL C 33  ? ARG C 40  ? VAL C 29  ARG C 36  
AA4 4 LYS C 79  ? GLU C 85  ? LYS C 75  GLU C 81  
AA4 5 LEU C 70  ? HIS C 75  ? LEU C 66  HIS C 71  
AA5 1 GLN C 89  ? ASP C 90  ? GLN C 85  ASP C 86  
AA5 2 LEU C 137 ? ILE C 139 ? LEU C 133 ILE C 135 
AA5 3 ILE C 145 ? LEU C 147 ? ILE C 141 LEU C 143 
AA6 1 VAL C 127 ? LEU C 128 ? VAL C 123 LEU C 124 
AA6 2 ARG C 154 ? ALA C 155 ? ARG C 150 ALA C 151 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 14  ? N ILE A 10  O VAL A 22  ? O VAL A 18  
AA1 2 3 N TYR A 23  ? N TYR A 19  O LEU A 36  ? O LEU A 32  
AA1 3 4 N ALA A 35  ? N ALA A 31  O PHE A 84  ? O PHE A 80  
AA1 4 5 O VAL A 83  ? O VAL A 79  N LEU A 71  ? N LEU A 67  
AA2 1 2 N GLN A 89  ? N GLN A 85  O ILE A 139 ? O ILE A 135 
AA2 2 3 N LEU A 138 ? N LEU A 134 O LYS A 146 ? O LYS A 142 
AA3 1 2 N LEU A 128 ? N LEU A 124 O ARG A 154 ? O ARG A 150 
AA4 1 2 N GLY C 15  ? N GLY C 11  O VAL C 22  ? O VAL C 18  
AA4 2 3 N ALA C 25  ? N ALA C 21  O VAL C 34  ? O VAL C 30  
AA4 3 4 N LYS C 37  ? N LYS C 33  O LEU C 82  ? O LEU C 78  
AA4 4 5 O VAL C 83  ? O VAL C 79  N LEU C 71  ? N LEU C 67  
AA5 1 2 N GLN C 89  ? N GLN C 85  O ILE C 139 ? O ILE C 135 
AA5 2 3 N LEU C 138 ? N LEU C 134 O LYS C 146 ? O LYS C 142 
AA6 1 2 N LEU C 128 ? N LEU C 124 O ARG C 154 ? O ARG C 150 
# 
_pdbx_entry_details.entry_id                   9ESN 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             N 
_pdbx_validate_rmsd_angle.auth_asym_id_1             B 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_2             B 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_3             B 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              346 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                90.54 
_pdbx_validate_rmsd_angle.angle_target_value         102.60 
_pdbx_validate_rmsd_angle.angle_deviation            -12.06 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL A 7   ? ? -122.21 -55.65  
2  1 GLU A 12  ? ? -163.47 116.62  
3  1 ASP A 127 ? ? -152.56 44.19   
4  1 ASP A 145 ? ? 66.46   85.30   
5  1 VAL A 164 ? ? 79.36   120.08  
6  1 SER A 181 ? ? -141.93 -157.48 
7  1 VAL B 175 ? ? 38.76   65.61   
8  1 TRP B 372 ? ? -32.30  112.17  
9  1 THR C 41  ? ? -127.02 -84.51  
10 1 ASP C 127 ? ? -151.47 44.29   
11 1 ASP C 145 ? ? 48.70   77.83   
12 1 VAL C 164 ? ? 76.71   123.38  
13 1 SER C 181 ? ? -145.93 -157.70 
14 1 TRP C 227 ? ? -150.36 88.38   
15 1 GLN C 287 ? ? -38.96  -35.86  
16 1 LYS C 291 ? ? -118.32 74.73   
17 1 GLN D 323 ? ? -174.50 77.55   
18 1 TRP D 372 ? ? -54.18  109.41  
19 1 ASN D 431 ? ? 55.30   -143.71 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 150 ? ? 0.219 'SIDE CHAIN' 
2 1 ARG B 400 ? ? 0.290 'SIDE CHAIN' 
3 1 ARG C 150 ? ? 0.159 'SIDE CHAIN' 
4 1 ARG C 217 ? ? 0.295 'SIDE CHAIN' 
5 1 ARG C 245 ? ? 0.114 'SIDE CHAIN' 
6 1 ARG C 260 ? ? 0.090 'SIDE CHAIN' 
7 1 ARG D 293 ? ? 0.111 'SIDE CHAIN' 
8 1 ARG D 410 ? ? 0.191 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1 A TPO 164 A TPO 160 ? THR 'modified residue' 
2 C TPO 164 C TPO 160 ? THR 'modified residue' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       913 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.59 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A HIS 295 ? A HIS 299 
2  1 Y 1 A LEU 296 ? A LEU 300 
3  1 Y 1 A ARG 297 ? A ARG 301 
4  1 Y 1 A LEU 298 ? A LEU 302 
5  1 Y 1 B HIS 433 ? B HIS 263 
6  1 Y 1 B HIS 434 ? B HIS 264 
7  1 Y 1 B HIS 435 ? B HIS 265 
8  1 Y 1 B HIS 436 ? B HIS 266 
9  1 Y 1 B HIS 437 ? B HIS 267 
10 1 Y 1 B HIS 438 ? B HIS 268 
11 1 Y 1 C GLY -3  ? C GLY 1   
12 1 Y 1 C PRO -2  ? C PRO 2   
13 1 Y 1 C GLY -1  ? C GLY 3   
14 1 Y 1 C ARG 297 ? C ARG 301 
15 1 Y 1 C LEU 298 ? C LEU 302 
16 1 Y 1 D HIS 433 ? D HIS 263 
17 1 Y 1 D HIS 434 ? D HIS 264 
18 1 Y 1 D HIS 435 ? D HIS 265 
19 1 Y 1 D HIS 436 ? D HIS 266 
20 1 Y 1 D HIS 437 ? D HIS 267 
21 1 Y 1 D HIS 438 ? D HIS 268 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
LEU N    N  N N 183 
LEU CA   C  N S 184 
LEU C    C  N N 185 
LEU O    O  N N 186 
LEU CB   C  N N 187 
LEU CG   C  N N 188 
LEU CD1  C  N N 189 
LEU CD2  C  N N 190 
LEU OXT  O  N N 191 
LEU H    H  N N 192 
LEU H2   H  N N 193 
LEU HA   H  N N 194 
LEU HB2  H  N N 195 
LEU HB3  H  N N 196 
LEU HG   H  N N 197 
LEU HD11 H  N N 198 
LEU HD12 H  N N 199 
LEU HD13 H  N N 200 
LEU HD21 H  N N 201 
LEU HD22 H  N N 202 
LEU HD23 H  N N 203 
LEU HXT  H  N N 204 
LYS N    N  N N 205 
LYS CA   C  N S 206 
LYS C    C  N N 207 
LYS O    O  N N 208 
LYS CB   C  N N 209 
LYS CG   C  N N 210 
LYS CD   C  N N 211 
LYS CE   C  N N 212 
LYS NZ   N  N N 213 
LYS OXT  O  N N 214 
LYS H    H  N N 215 
LYS H2   H  N N 216 
LYS HA   H  N N 217 
LYS HB2  H  N N 218 
LYS HB3  H  N N 219 
LYS HG2  H  N N 220 
LYS HG3  H  N N 221 
LYS HD2  H  N N 222 
LYS HD3  H  N N 223 
LYS HE2  H  N N 224 
LYS HE3  H  N N 225 
LYS HZ1  H  N N 226 
LYS HZ2  H  N N 227 
LYS HZ3  H  N N 228 
LYS HXT  H  N N 229 
MET N    N  N N 230 
MET CA   C  N S 231 
MET C    C  N N 232 
MET O    O  N N 233 
MET CB   C  N N 234 
MET CG   C  N N 235 
MET SD   S  N N 236 
MET CE   C  N N 237 
MET OXT  O  N N 238 
MET H    H  N N 239 
MET H2   H  N N 240 
MET HA   H  N N 241 
MET HB2  H  N N 242 
MET HB3  H  N N 243 
MET HG2  H  N N 244 
MET HG3  H  N N 245 
MET HE1  H  N N 246 
MET HE2  H  N N 247 
MET HE3  H  N N 248 
MET HXT  H  N N 249 
PHE N    N  N N 250 
PHE CA   C  N S 251 
PHE C    C  N N 252 
PHE O    O  N N 253 
PHE CB   C  N N 254 
PHE CG   C  Y N 255 
PHE CD1  C  Y N 256 
PHE CD2  C  Y N 257 
PHE CE1  C  Y N 258 
PHE CE2  C  Y N 259 
PHE CZ   C  Y N 260 
PHE OXT  O  N N 261 
PHE H    H  N N 262 
PHE H2   H  N N 263 
PHE HA   H  N N 264 
PHE HB2  H  N N 265 
PHE HB3  H  N N 266 
PHE HD1  H  N N 267 
PHE HD2  H  N N 268 
PHE HE1  H  N N 269 
PHE HE2  H  N N 270 
PHE HZ   H  N N 271 
PHE HXT  H  N N 272 
PRO N    N  N N 273 
PRO CA   C  N S 274 
PRO C    C  N N 275 
PRO O    O  N N 276 
PRO CB   C  N N 277 
PRO CG   C  N N 278 
PRO CD   C  N N 279 
PRO OXT  O  N N 280 
PRO H    H  N N 281 
PRO HA   H  N N 282 
PRO HB2  H  N N 283 
PRO HB3  H  N N 284 
PRO HG2  H  N N 285 
PRO HG3  H  N N 286 
PRO HD2  H  N N 287 
PRO HD3  H  N N 288 
PRO HXT  H  N N 289 
SER N    N  N N 290 
SER CA   C  N S 291 
SER C    C  N N 292 
SER O    O  N N 293 
SER CB   C  N N 294 
SER OG   O  N N 295 
SER OXT  O  N N 296 
SER H    H  N N 297 
SER H2   H  N N 298 
SER HA   H  N N 299 
SER HB2  H  N N 300 
SER HB3  H  N N 301 
SER HG   H  N N 302 
SER HXT  H  N N 303 
THR N    N  N N 304 
THR CA   C  N S 305 
THR C    C  N N 306 
THR O    O  N N 307 
THR CB   C  N R 308 
THR OG1  O  N N 309 
THR CG2  C  N N 310 
THR OXT  O  N N 311 
THR H    H  N N 312 
THR H2   H  N N 313 
THR HA   H  N N 314 
THR HB   H  N N 315 
THR HG1  H  N N 316 
THR HG21 H  N N 317 
THR HG22 H  N N 318 
THR HG23 H  N N 319 
THR HXT  H  N N 320 
TPO N    N  N N 321 
TPO CA   C  N S 322 
TPO CB   C  N R 323 
TPO CG2  C  N N 324 
TPO OG1  O  N N 325 
TPO P    P  N N 326 
TPO O1P  O  N N 327 
TPO O2P  O  N N 328 
TPO O3P  O  N N 329 
TPO C    C  N N 330 
TPO O    O  N N 331 
TPO OXT  O  N N 332 
TPO H    H  N N 333 
TPO H2   H  N N 334 
TPO HA   H  N N 335 
TPO HB   H  N N 336 
TPO HG21 H  N N 337 
TPO HG22 H  N N 338 
TPO HG23 H  N N 339 
TPO HOP2 H  N N 340 
TPO HOP3 H  N N 341 
TPO HXT  H  N N 342 
TRP N    N  N N 343 
TRP CA   C  N S 344 
TRP C    C  N N 345 
TRP O    O  N N 346 
TRP CB   C  N N 347 
TRP CG   C  Y N 348 
TRP CD1  C  Y N 349 
TRP CD2  C  Y N 350 
TRP NE1  N  Y N 351 
TRP CE2  C  Y N 352 
TRP CE3  C  Y N 353 
TRP CZ2  C  Y N 354 
TRP CZ3  C  Y N 355 
TRP CH2  C  Y N 356 
TRP OXT  O  N N 357 
TRP H    H  N N 358 
TRP H2   H  N N 359 
TRP HA   H  N N 360 
TRP HB2  H  N N 361 
TRP HB3  H  N N 362 
TRP HD1  H  N N 363 
TRP HE1  H  N N 364 
TRP HE3  H  N N 365 
TRP HZ2  H  N N 366 
TRP HZ3  H  N N 367 
TRP HH2  H  N N 368 
TRP HXT  H  N N 369 
TYR N    N  N N 370 
TYR CA   C  N S 371 
TYR C    C  N N 372 
TYR O    O  N N 373 
TYR CB   C  N N 374 
TYR CG   C  Y N 375 
TYR CD1  C  Y N 376 
TYR CD2  C  Y N 377 
TYR CE1  C  Y N 378 
TYR CE2  C  Y N 379 
TYR CZ   C  Y N 380 
TYR OH   O  N N 381 
TYR OXT  O  N N 382 
TYR H    H  N N 383 
TYR H2   H  N N 384 
TYR HA   H  N N 385 
TYR HB2  H  N N 386 
TYR HB3  H  N N 387 
TYR HD1  H  N N 388 
TYR HD2  H  N N 389 
TYR HE1  H  N N 390 
TYR HE2  H  N N 391 
TYR HH   H  N N 392 
TYR HXT  H  N N 393 
UUS C4   C  N N 394 
UUS C5   C  N N 395 
UUS C6   C  N N 396 
UUS N    N  N N 397 
UUS C    C  N N 398 
UUS O    O  N N 399 
UUS C1   C  N N 400 
UUS C2   C  N N 401 
UUS C3   C  N N 402 
UUS O1   O  N N 403 
UUS BR   BR N N 404 
UUS H1   H  N N 405 
UUS H2   H  N N 406 
UUS H3   H  N N 407 
UUS H4   H  N N 408 
UUS H5   H  N N 409 
UUS H6   H  N N 410 
UUS H7   H  N N 411 
UUS H8   H  N N 412 
VAL N    N  N N 413 
VAL CA   C  N S 414 
VAL C    C  N N 415 
VAL O    O  N N 416 
VAL CB   C  N N 417 
VAL CG1  C  N N 418 
VAL CG2  C  N N 419 
VAL OXT  O  N N 420 
VAL H    H  N N 421 
VAL H2   H  N N 422 
VAL HA   H  N N 423 
VAL HB   H  N N 424 
VAL HG11 H  N N 425 
VAL HG12 H  N N 426 
VAL HG13 H  N N 427 
VAL HG21 H  N N 428 
VAL HG22 H  N N 429 
VAL HG23 H  N N 430 
VAL HXT  H  N N 431 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TPO N   CA   sing N N 306 
TPO N   H    sing N N 307 
TPO N   H2   sing N N 308 
TPO CA  CB   sing N N 309 
TPO CA  C    sing N N 310 
TPO CA  HA   sing N N 311 
TPO CB  CG2  sing N N 312 
TPO CB  OG1  sing N N 313 
TPO CB  HB   sing N N 314 
TPO CG2 HG21 sing N N 315 
TPO CG2 HG22 sing N N 316 
TPO CG2 HG23 sing N N 317 
TPO OG1 P    sing N N 318 
TPO P   O1P  doub N N 319 
TPO P   O2P  sing N N 320 
TPO P   O3P  sing N N 321 
TPO O2P HOP2 sing N N 322 
TPO O3P HOP3 sing N N 323 
TPO C   O    doub N N 324 
TPO C   OXT  sing N N 325 
TPO OXT HXT  sing N N 326 
TRP N   CA   sing N N 327 
TRP N   H    sing N N 328 
TRP N   H2   sing N N 329 
TRP CA  C    sing N N 330 
TRP CA  CB   sing N N 331 
TRP CA  HA   sing N N 332 
TRP C   O    doub N N 333 
TRP C   OXT  sing N N 334 
TRP CB  CG   sing N N 335 
TRP CB  HB2  sing N N 336 
TRP CB  HB3  sing N N 337 
TRP CG  CD1  doub Y N 338 
TRP CG  CD2  sing Y N 339 
TRP CD1 NE1  sing Y N 340 
TRP CD1 HD1  sing N N 341 
TRP CD2 CE2  doub Y N 342 
TRP CD2 CE3  sing Y N 343 
TRP NE1 CE2  sing Y N 344 
TRP NE1 HE1  sing N N 345 
TRP CE2 CZ2  sing Y N 346 
TRP CE3 CZ3  doub Y N 347 
TRP CE3 HE3  sing N N 348 
TRP CZ2 CH2  doub Y N 349 
TRP CZ2 HZ2  sing N N 350 
TRP CZ3 CH2  sing Y N 351 
TRP CZ3 HZ3  sing N N 352 
TRP CH2 HH2  sing N N 353 
TRP OXT HXT  sing N N 354 
TYR N   CA   sing N N 355 
TYR N   H    sing N N 356 
TYR N   H2   sing N N 357 
TYR CA  C    sing N N 358 
TYR CA  CB   sing N N 359 
TYR CA  HA   sing N N 360 
TYR C   O    doub N N 361 
TYR C   OXT  sing N N 362 
TYR CB  CG   sing N N 363 
TYR CB  HB2  sing N N 364 
TYR CB  HB3  sing N N 365 
TYR CG  CD1  doub Y N 366 
TYR CG  CD2  sing Y N 367 
TYR CD1 CE1  sing Y N 368 
TYR CD1 HD1  sing N N 369 
TYR CD2 CE2  doub Y N 370 
TYR CD2 HD2  sing N N 371 
TYR CE1 CZ   doub Y N 372 
TYR CE1 HE1  sing N N 373 
TYR CE2 CZ   sing Y N 374 
TYR CE2 HE2  sing N N 375 
TYR CZ  OH   sing N N 376 
TYR OH  HH   sing N N 377 
TYR OXT HXT  sing N N 378 
UUS O   C    doub N N 379 
UUS C2  O1   sing N N 380 
UUS C2  C1   sing N N 381 
UUS C   C6   sing N N 382 
UUS C   N    sing N N 383 
UUS C6  C5   doub N N 384 
UUS C1  N    sing N N 385 
UUS N   C3   sing N N 386 
UUS C5  BR   sing N N 387 
UUS C5  C4   sing N N 388 
UUS C3  C4   doub N N 389 
UUS C4  H1   sing N N 390 
UUS C6  H2   sing N N 391 
UUS C1  H3   sing N N 392 
UUS C1  H4   sing N N 393 
UUS C2  H5   sing N N 394 
UUS C2  H6   sing N N 395 
UUS C3  H7   sing N N 396 
UUS O1  H8   sing N N 397 
VAL N   CA   sing N N 398 
VAL N   H    sing N N 399 
VAL N   H2   sing N N 400 
VAL CA  C    sing N N 401 
VAL CA  CB   sing N N 402 
VAL CA  HA   sing N N 403 
VAL C   O    doub N N 404 
VAL C   OXT  sing N N 405 
VAL CB  CG1  sing N N 406 
VAL CB  CG2  sing N N 407 
VAL CB  HB   sing N N 408 
VAL CG1 HG11 sing N N 409 
VAL CG1 HG12 sing N N 410 
VAL CG1 HG13 sing N N 411 
VAL CG2 HG21 sing N N 412 
VAL CG2 HG22 sing N N 413 
VAL CG2 HG23 sing N N 414 
VAL OXT HXT  sing N N 415 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/N009738/1 1 
'Medical Research Council (MRC, United Kingdom)' 'United Kingdom' MR/V029142/1 2 
'Cancer Research UK'                             'United Kingdom' C2115/A21421 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GUC 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9ESN 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013481 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007454 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006759 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
BR 35 35 17.1822 2.1723  5.2368 16.5796 5.6388 0.2609  3.9859 41.4328 -0.0527  
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P  15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2466   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0257   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . GLY A 1 1   ? -19.642 -5.719  25.627  1   109.96 ? -3  GLY A N   1 
ATOM   2    C  CA  . GLY A 1 1   ? -20.997 -6.244  25.367  1   109.97 ? -3  GLY A CA  1 
ATOM   3    C  C   . GLY A 1 1   ? -21.678 -6.614  26.663  1   116.78 ? -3  GLY A C   1 
ATOM   4    O  O   . GLY A 1 1   ? -21.683 -5.779  27.587  1   118.56 ? -3  GLY A O   1 
ATOM   5    N  N   . PRO A 1 2   ? -22.26  -7.822  26.794  1   127.87 ? -2  PRO A N   1 
ATOM   6    C  CA  . PRO A 1 2   ? -22.835 -8.239  28.064  1   125.37 ? -2  PRO A CA  1 
ATOM   7    C  C   . PRO A 1 2   ? -21.83  -8.758  29.077  1   115.66 ? -2  PRO A C   1 
ATOM   8    O  O   . PRO A 1 2   ? -22.022 -9.879  29.579  1   111.38 ? -2  PRO A O   1 
ATOM   9    C  CB  . PRO A 1 2   ? -23.754 -9.359  27.574  1   131.64 ? -2  PRO A CB  1 
ATOM   10   C  CG  . PRO A 1 2   ? -22.991 -9.987  26.436  1   127.66 ? -2  PRO A CG  1 
ATOM   11   C  CD  . PRO A 1 2   ? -22.422 -8.781  25.718  1   130.92 ? -2  PRO A CD  1 
ATOM   12   N  N   . GLY A 1 3   ? -20.787 -7.986  29.382  1   103.12 ? -1  GLY A N   1 
ATOM   13   C  CA  . GLY A 1 3   ? -19.754 -8.532  30.28   1   104.27 ? -1  GLY A CA  1 
ATOM   14   C  C   . GLY A 1 3   ? -18.67  -7.549  30.661  1   106.46 ? -1  GLY A C   1 
ATOM   15   O  O   . GLY A 1 3   ? -18.45  -6.592  29.897  1   101.4  ? -1  GLY A O   1 
ATOM   16   N  N   . SER A 1 4   ? -18.014 -7.79   31.799  1   117.66 ? 0   SER A N   1 
ATOM   17   C  CA  . SER A 1 4   ? -16.917 -6.916  32.292  1   118.66 ? 0   SER A CA  1 
ATOM   18   C  C   . SER A 1 4   ? -15.846 -7.796  32.945  1   106.37 ? 0   SER A C   1 
ATOM   19   O  O   . SER A 1 4   ? -16.19  -8.913  33.365  1   115.47 ? 0   SER A O   1 
ATOM   20   C  CB  . SER A 1 4   ? -17.439 -5.893  33.253  1   112.7  ? 0   SER A CB  1 
ATOM   21   O  OG  . SER A 1 4   ? -17.959 -6.519  34.418  1   122.68 ? 0   SER A OG  1 
ATOM   22   N  N   . MET A 1 5   ? -14.615 -7.302  33.069  1   93.16  ? 1   MET A N   1 
ATOM   23   C  CA  . MET A 1 5   ? -13.539 -8.141  33.579  1   84.96  ? 1   MET A CA  1 
ATOM   24   C  C   . MET A 1 5   ? -13.752 -8.526  35.042  1   81.61  ? 1   MET A C   1 
ATOM   25   O  O   . MET A 1 5   ? -13.398 -9.635  35.429  1   84.23  ? 1   MET A O   1 
ATOM   26   C  CB  . MET A 1 5   ? -12.16  -7.503  33.397  1   83.29  ? 1   MET A CB  1 
ATOM   27   C  CG  . MET A 1 5   ? -11.714 -7.443  31.957  1   80.82  ? 1   MET A CG  1 
ATOM   28   S  SD  . MET A 1 5   ? -12.356 -8.816  30.975  1   77.94  ? 1   MET A SD  1 
ATOM   29   C  CE  . MET A 1 5   ? -11.081 -10.062 31.188  1   77.29  ? 1   MET A CE  1 
ATOM   30   N  N   . GLU A 1 6   ? -14.345 -7.624  35.831  1   81.73  ? 2   GLU A N   1 
ATOM   31   C  CA  . GLU A 1 6   ? -14.713 -7.857  37.221  1   87.26  ? 2   GLU A CA  1 
ATOM   32   C  C   . GLU A 1 6   ? -15.304 -9.242  37.488  1   74.96  ? 2   GLU A C   1 
ATOM   33   O  O   . GLU A 1 6   ? -15.155 -9.744  38.588  1   77.64  ? 2   GLU A O   1 
ATOM   34   C  CB  . GLU A 1 6   ? -15.633 -6.749  37.749  1   108.17 ? 2   GLU A CB  1 
ATOM   35   C  CG  . GLU A 1 6   ? -14.895 -5.448  38.052  1   126.07 ? 2   GLU A CG  1 
ATOM   36   C  CD  . GLU A 1 6   ? -13.611 -5.69   38.829  1   136.95 ? 2   GLU A CD  1 
ATOM   37   O  OE1 . GLU A 1 6   ? -13.7   -6.306  39.917  1   137.07 ? 2   GLU A OE1 1 
ATOM   38   O  OE2 . GLU A 1 6   ? -12.527 -5.295  38.335  1   144.31 ? 2   GLU A OE2 1 
ATOM   39   N  N   . ASN A 1 7   ? -16.012 -9.836  36.519  1   73.4   ? 3   ASN A N   1 
ATOM   40   C  CA  . ASN A 1 7   ? -16.729 -11.088 36.741  1   71.56  ? 3   ASN A CA  1 
ATOM   41   C  C   . ASN A 1 7   ? -15.885 -12.318 36.414  1   66.86  ? 3   ASN A C   1 
ATOM   42   O  O   . ASN A 1 7   ? -16.371 -13.434 36.573  1   67.33  ? 3   ASN A O   1 
ATOM   43   C  CB  . ASN A 1 7   ? -18.014 -11.215 35.924  1   75.34  ? 3   ASN A CB  1 
ATOM   44   C  CG  . ASN A 1 7   ? -19.094 -10.244 36.347  1   87.65  ? 3   ASN A CG  1 
ATOM   45   O  OD1 . ASN A 1 7   ? -19.242 -9.944  37.542  1   86.02  ? 3   ASN A OD1 1 
ATOM   46   N  ND2 . ASN A 1 7   ? -19.843 -9.728  35.375  1   93.34  ? 3   ASN A ND2 1 
ATOM   47   N  N   . PHE A 1 8   ? -14.658 -12.127 35.911  1   61.83  ? 4   PHE A N   1 
ATOM   48   C  CA  . PHE A 1 8   ? -13.786 -13.252 35.629  1   60.29  ? 4   PHE A CA  1 
ATOM   49   C  C   . PHE A 1 8   ? -12.665 -13.356 36.661  1   65.75  ? 4   PHE A C   1 
ATOM   50   O  O   . PHE A 1 8   ? -12.155 -12.35  37.165  1   70.53  ? 4   PHE A O   1 
ATOM   51   C  CB  . PHE A 1 8   ? -13.269 -13.12  34.211  1   56.75  ? 4   PHE A CB  1 
ATOM   52   C  CG  . PHE A 1 8   ? -14.35  -13.185 33.149  1   58.95  ? 4   PHE A CG  1 
ATOM   53   C  CD1 . PHE A 1 8   ? -14.866 -14.413 32.739  1   58.27  ? 4   PHE A CD1 1 
ATOM   54   C  CD2 . PHE A 1 8   ? -14.821 -12.026 32.52   1   58.88  ? 4   PHE A CD2 1 
ATOM   55   C  CE1 . PHE A 1 8   ? -15.826 -14.481 31.715  1   55.65  ? 4   PHE A CE1 1 
ATOM   56   C  CE2 . PHE A 1 8   ? -15.803 -12.102 31.532  1   56.84  ? 4   PHE A CE2 1 
ATOM   57   C  CZ  . PHE A 1 8   ? -16.29  -13.331 31.106  1   51.64  ? 4   PHE A CZ  1 
ATOM   58   N  N   . GLN A 1 9   ? -12.36  -14.605 37.027  1   65.03  ? 5   GLN A N   1 
ATOM   59   C  CA  . GLN A 1 9   ? -11.205 -14.956 37.839  1   66.51  ? 5   GLN A CA  1 
ATOM   60   C  C   . GLN A 1 9   ? -10.236 -15.718 36.944  1   64.56  ? 5   GLN A C   1 
ATOM   61   O  O   . GLN A 1 9   ? -10.572 -16.804 36.498  1   62.92  ? 5   GLN A O   1 
ATOM   62   C  CB  . GLN A 1 9   ? -11.652 -15.849 39.004  1   71.51  ? 5   GLN A CB  1 
ATOM   63   C  CG  . GLN A 1 9   ? -10.557 -16.215 40.003  1   78.7   ? 5   GLN A CG  1 
ATOM   64   C  CD  . GLN A 1 9   ? -9.922  -15.008 40.669  1   86.63  ? 5   GLN A CD  1 
ATOM   65   O  OE1 . GLN A 1 9   ? -10.598 -14.055 41.086  1   90.98  ? 5   GLN A OE1 1 
ATOM   66   N  NE2 . GLN A 1 9   ? -8.602  -15.026 40.773  1   88.03  ? 5   GLN A NE2 1 
ATOM   67   N  N   . LYS A 1 10  ? -9.059  -15.144 36.663  1   64.65  ? 6   LYS A N   1 
ATOM   68   C  CA  . LYS A 1 10  ? -8.009  -15.833 35.923  1   64.98  ? 6   LYS A CA  1 
ATOM   69   C  C   . LYS A 1 10  ? -7.564  -17.071 36.694  1   62.98  ? 6   LYS A C   1 
ATOM   70   O  O   . LYS A 1 10  ? -7.658  -17.082 37.902  1   62.96  ? 6   LYS A O   1 
ATOM   71   C  CB  . LYS A 1 10  ? -6.849  -14.884 35.613  1   70.28  ? 6   LYS A CB  1 
ATOM   72   C  CG  . LYS A 1 10  ? -7.255  -13.85  34.56   1   80.59  ? 6   LYS A CG  1 
ATOM   73   C  CD  . LYS A 1 10  ? -6.099  -13.047 33.972  1   91.13  ? 6   LYS A CD  1 
ATOM   74   C  CE  . LYS A 1 10  ? -6.42   -12.523 32.599  1   84.48  ? 6   LYS A CE  1 
ATOM   75   N  NZ  . LYS A 1 10  ? -7.443  -11.486 32.718  1   85.71  ? 6   LYS A NZ  1 
ATOM   76   N  N   . VAL A 1 11  ? -7.147  -18.127 35.978  1   67.36  ? 7   VAL A N   1 
ATOM   77   C  CA  . VAL A 1 11  ? -6.859  -19.425 36.58   1   69.98  ? 7   VAL A CA  1 
ATOM   78   C  C   . VAL A 1 11  ? -5.416  -19.809 36.27   1   71.37  ? 7   VAL A C   1 
ATOM   79   O  O   . VAL A 1 11  ? -4.659  -20.064 37.195  1   82.41  ? 7   VAL A O   1 
ATOM   80   C  CB  . VAL A 1 11  ? -7.84   -20.546 36.17   1   66.72  ? 7   VAL A CB  1 
ATOM   81   C  CG1 . VAL A 1 11  ? -7.353  -21.932 36.57   1   67.29  ? 7   VAL A CG1 1 
ATOM   82   C  CG2 . VAL A 1 11  ? -9.227  -20.313 36.729  1   61.19  ? 7   VAL A CG2 1 
ATOM   83   N  N   . GLU A 1 12  ? -5.063  -19.834 34.975  1   70.7   ? 8   GLU A N   1 
ATOM   84   C  CA  . GLU A 1 12  ? -3.693  -19.991 34.51   1   75.24  ? 8   GLU A CA  1 
ATOM   85   C  C   . GLU A 1 12  ? -3.587  -19.484 33.074  1   75.47  ? 8   GLU A C   1 
ATOM   86   O  O   . GLU A 1 12  ? -4.603  -19.196 32.441  1   74.58  ? 8   GLU A O   1 
ATOM   87   C  CB  . GLU A 1 12  ? -3.225  -21.443 34.58   1   79.99  ? 8   GLU A CB  1 
ATOM   88   C  CG  . GLU A 1 12  ? -3.954  -22.346 33.594  1   79.88  ? 8   GLU A CG  1 
ATOM   89   C  CD  . GLU A 1 12  ? -3.904  -23.819 33.914  1   85.37  ? 8   GLU A CD  1 
ATOM   90   O  OE1 . GLU A 1 12  ? -4.192  -24.142 35.085  1   89.61  ? 8   GLU A OE1 1 
ATOM   91   O  OE2 . GLU A 1 12  ? -3.638  -24.617 32.987  1   88.19  ? 8   GLU A OE2 1 
ATOM   92   N  N   . LYS A 1 13  ? -2.342  -19.335 32.592  1   73.41  ? 9   LYS A N   1 
ATOM   93   C  CA  . LYS A 1 13  ? -2.079  -18.982 31.21   1   70.37  ? 9   LYS A CA  1 
ATOM   94   C  C   . LYS A 1 13  ? -2.103  -20.278 30.397  1   65.9   ? 9   LYS A C   1 
ATOM   95   O  O   . LYS A 1 13  ? -1.46   -21.245 30.794  1   69.69  ? 9   LYS A O   1 
ATOM   96   C  CB  . LYS A 1 13  ? -0.738  -18.241 31.146  1   72.67  ? 9   LYS A CB  1 
ATOM   97   C  CG  . LYS A 1 13  ? -0.459  -17.75  29.735  1   84.6   ? 9   LYS A CG  1 
ATOM   98   C  CD  . LYS A 1 13  ? 0.903   -18.065 29.135  1   89.04  ? 9   LYS A CD  1 
ATOM   99   C  CE  . LYS A 1 13  ? 1.8     -16.885 29.025  1   93.6   ? 9   LYS A CE  1 
ATOM   100  N  NZ  . LYS A 1 13  ? 2.804   -17.097 27.979  1   109.81 ? 9   LYS A NZ  1 
ATOM   101  N  N   . ILE A 1 14  ? -2.86   -20.317 29.294  1   57.44  ? 10  ILE A N   1 
ATOM   102  C  CA  . ILE A 1 14  ? -3.008  -21.557 28.548  1   58.49  ? 10  ILE A CA  1 
ATOM   103  C  C   . ILE A 1 14  ? -2.337  -21.465 27.187  1   62.79  ? 10  ILE A C   1 
ATOM   104  O  O   . ILE A 1 14  ? -2.23   -22.472 26.485  1   75.83  ? 10  ILE A O   1 
ATOM   105  C  CB  . ILE A 1 14  ? -4.469  -22.015 28.39   1   57.2   ? 10  ILE A CB  1 
ATOM   106  C  CG1 . ILE A 1 14  ? -5.368  -20.906 27.865  1   57.41  ? 10  ILE A CG1 1 
ATOM   107  C  CG2 . ILE A 1 14  ? -4.987  -22.627 29.693  1   61.28  ? 10  ILE A CG2 1 
ATOM   108  C  CD1 . ILE A 1 14  ? -6.773  -21.358 27.513  1   55.47  ? 10  ILE A CD1 1 
ATOM   109  N  N   . GLY A 1 15  ? -1.892  -20.267 26.81   1   68.67  ? 11  GLY A N   1 
ATOM   110  C  CA  . GLY A 1 15  ? -1.452  -20.059 25.438  1   71.45  ? 11  GLY A CA  1 
ATOM   111  C  C   . GLY A 1 15  ? -0.907  -18.653 25.209  1   77.6   ? 11  GLY A C   1 
ATOM   112  O  O   . GLY A 1 15  ? -0.978  -17.782 26.089  1   79.45  ? 11  GLY A O   1 
ATOM   113  N  N   . GLU A 1 16  ? -0.367  -18.449 24.006  1   87.91  ? 12  GLU A N   1 
ATOM   114  C  CA  . GLU A 1 16  ? 0.207   -17.166 23.65   1   99.69  ? 12  GLU A CA  1 
ATOM   115  C  C   . GLU A 1 16  ? 0.356   -17.11  22.134  1   113.17 ? 12  GLU A C   1 
ATOM   116  O  O   . GLU A 1 16  ? 1.052   -17.928 21.541  1   113    ? 12  GLU A O   1 
ATOM   117  C  CB  . GLU A 1 16  ? 1.531   -17.016 24.4    1   98.57  ? 12  GLU A CB  1 
ATOM   118  C  CG  . GLU A 1 16  ? 2.214   -15.671 24.174  1   116.4  ? 12  GLU A CG  1 
ATOM   119  C  CD  . GLU A 1 16  ? 3.506   -15.461 24.935  1   131.41 ? 12  GLU A CD  1 
ATOM   120  O  OE1 . GLU A 1 16  ? 3.912   -16.413 25.643  1   141.9  ? 12  GLU A OE1 1 
ATOM   121  O  OE2 . GLU A 1 16  ? 4.101   -14.365 24.801  1   131.87 ? 12  GLU A OE2 1 
ATOM   122  N  N   . GLY A 1 17  ? -0.362  -16.178 21.504  1   124.57 ? 13  GLY A N   1 
ATOM   123  C  CA  . GLY A 1 17  ? -0.162  -15.894 20.088  1   124.34 ? 13  GLY A CA  1 
ATOM   124  C  C   . GLY A 1 17  ? 0.751   -14.683 19.933  1   128.5  ? 13  GLY A C   1 
ATOM   125  O  O   . GLY A 1 17  ? 1.409   -14.29  20.9    1   122.84 ? 13  GLY A O   1 
ATOM   126  N  N   . THR A 1 18  ? 0.778   -14.099 18.726  1   119.6  ? 14  THR A N   1 
ATOM   127  C  CA  . THR A 1 18  ? 1.62    -12.942 18.461  1   116.34 ? 14  THR A CA  1 
ATOM   128  C  C   . THR A 1 18  ? 0.86    -11.668 18.834  1   113.55 ? 14  THR A C   1 
ATOM   129  O  O   . THR A 1 18  ? 1.42    -10.576 18.825  1   109.05 ? 14  THR A O   1 
ATOM   130  C  CB  . THR A 1 18  ? 2.123   -12.963 17.015  1   120.83 ? 14  THR A CB  1 
ATOM   131  O  OG1 . THR A 1 18  ? 0.976   -12.753 16.198  1   129.43 ? 14  THR A OG1 1 
ATOM   132  C  CG2 . THR A 1 18  ? 2.799   -14.273 16.635  1   106.41 ? 14  THR A CG2 1 
ATOM   133  N  N   . TYR A 1 19  ? -0.421  -11.838 19.196  1   119    ? 15  TYR A N   1 
ATOM   134  C  CA  . TYR A 1 19  ? -1.307  -10.779 19.666  1   117.36 ? 15  TYR A CA  1 
ATOM   135  C  C   . TYR A 1 19  ? -1.178  -10.586 21.176  1   119.01 ? 15  TYR A C   1 
ATOM   136  O  O   . TYR A 1 19  ? -1.462  -9.504  21.707  1   100.28 ? 15  TYR A O   1 
ATOM   137  C  CB  . TYR A 1 19  ? -2.74   -11.275 19.462  1   130.58 ? 15  TYR A CB  1 
ATOM   138  C  CG  . TYR A 1 19  ? -2.921  -12.756 19.777  1   149.38 ? 15  TYR A CG  1 
ATOM   139  C  CD1 . TYR A 1 19  ? -3.102  -13.217 21.088  1   164.77 ? 15  TYR A CD1 1 
ATOM   140  C  CD2 . TYR A 1 19  ? -2.9    -13.702 18.751  1   147.38 ? 15  TYR A CD2 1 
ATOM   141  C  CE1 . TYR A 1 19  ? -3.254  -14.573 21.358  1   181.36 ? 15  TYR A CE1 1 
ATOM   142  C  CE2 . TYR A 1 19  ? -3.06   -15.054 19.014  1   153.66 ? 15  TYR A CE2 1 
ATOM   143  C  CZ  . TYR A 1 19  ? -3.25   -15.494 20.318  1   175.57 ? 15  TYR A CZ  1 
ATOM   144  O  OH  . TYR A 1 19  ? -3.404  -16.836 20.579  1   171.78 ? 15  TYR A OH  1 
ATOM   145  N  N   . GLY A 1 20  ? -0.805  -11.674 21.865  1   115.81 ? 16  GLY A N   1 
ATOM   146  C  CA  . GLY A 1 20  ? -0.765  -11.66  23.315  1   96.62  ? 16  GLY A CA  1 
ATOM   147  C  C   . GLY A 1 20  ? -1.03   -13.033 23.923  1   85.06  ? 16  GLY A C   1 
ATOM   148  O  O   . GLY A 1 20  ? -0.794  -14.075 23.316  1   87.26  ? 16  GLY A O   1 
ATOM   149  N  N   . VAL A 1 21  ? -1.548  -13.01  25.144  1   81.11  ? 17  VAL A N   1 
ATOM   150  C  CA  . VAL A 1 21  ? -1.666  -14.211 25.952  1   85.08  ? 17  VAL A CA  1 
ATOM   151  C  C   . VAL A 1 21  ? -3.12   -14.69  25.979  1   76.97  ? 17  VAL A C   1 
ATOM   152  O  O   . VAL A 1 21  ? -4.042  -13.887 25.889  1   73.28  ? 17  VAL A O   1 
ATOM   153  C  CB  . VAL A 1 21  ? -1.133  -13.906 27.37   1   90.34  ? 17  VAL A CB  1 
ATOM   154  C  CG1 . VAL A 1 21  ? -1.571  -12.547 27.904  1   93.92  ? 17  VAL A CG1 1 
ATOM   155  C  CG2 . VAL A 1 21  ? -1.511  -14.971 28.388  1   98.63  ? 17  VAL A CG2 1 
ATOM   156  N  N   . VAL A 1 22  ? -3.31   -16.005 26.137  1   65.3   ? 18  VAL A N   1 
ATOM   157  C  CA  . VAL A 1 22  ? -4.618  -16.539 26.454  1   55.35  ? 18  VAL A CA  1 
ATOM   158  C  C   . VAL A 1 22  ? -4.603  -17.139 27.858  1   59.28  ? 18  VAL A C   1 
ATOM   159  O  O   . VAL A 1 22  ? -3.67   -17.842 28.241  1   67.27  ? 18  VAL A O   1 
ATOM   160  C  CB  . VAL A 1 22  ? -5.042  -17.553 25.387  1   51.79  ? 18  VAL A CB  1 
ATOM   161  C  CG1 . VAL A 1 22  ? -6.468  -18.028 25.637  1   54.37  ? 18  VAL A CG1 1 
ATOM   162  C  CG2 . VAL A 1 22  ? -4.905  -16.968 23.977  1   52.62  ? 18  VAL A CG2 1 
ATOM   163  N  N   . TYR A 1 23  ? -5.641  -16.834 28.642  1   58.77  ? 19  TYR A N   1 
ATOM   164  C  CA  . TYR A 1 23  ? -5.799  -17.409 29.965  1   61.66  ? 19  TYR A CA  1 
ATOM   165  C  C   . TYR A 1 23  ? -7.075  -18.241 30.036  1   59.93  ? 19  TYR A C   1 
ATOM   166  O  O   . TYR A 1 23  ? -8.096  -17.863 29.479  1   61.11  ? 19  TYR A O   1 
ATOM   167  C  CB  . TYR A 1 23  ? -5.961  -16.325 31.029  1   67.77  ? 19  TYR A CB  1 
ATOM   168  C  CG  . TYR A 1 23  ? -4.783  -15.381 31.221  1   81.86  ? 19  TYR A CG  1 
ATOM   169  C  CD1 . TYR A 1 23  ? -4.544  -14.354 30.309  1   90.21  ? 19  TYR A CD1 1 
ATOM   170  C  CD2 . TYR A 1 23  ? -3.949  -15.475 32.334  1   82.8   ? 19  TYR A CD2 1 
ATOM   171  C  CE1 . TYR A 1 23  ? -3.49   -13.471 30.483  1   96.37  ? 19  TYR A CE1 1 
ATOM   172  C  CE2 . TYR A 1 23  ? -2.891  -14.599 32.514  1   92.5   ? 19  TYR A CE2 1 
ATOM   173  C  CZ  . TYR A 1 23  ? -2.657  -13.6   31.582  1   103.92 ? 19  TYR A CZ  1 
ATOM   174  O  OH  . TYR A 1 23  ? -1.61   -12.736 31.755  1   117.98 ? 19  TYR A OH  1 
ATOM   175  N  N   . LYS A 1 24  ? -7.027  -19.347 30.786  1   58.63  ? 20  LYS A N   1 
ATOM   176  C  CA  . LYS A 1 24  ? -8.237  -20.006 31.249  1   56.98  ? 20  LYS A CA  1 
ATOM   177  C  C   . LYS A 1 24  ? -8.806  -19.168 32.392  1   58.48  ? 20  LYS A C   1 
ATOM   178  O  O   . LYS A 1 24  ? -8.07   -18.794 33.303  1   58.72  ? 20  LYS A O   1 
ATOM   179  C  CB  . LYS A 1 24  ? -7.953  -21.458 31.656  1   55.75  ? 20  LYS A CB  1 
ATOM   180  C  CG  . LYS A 1 24  ? -9.075  -22.181 32.371  1   54.43  ? 20  LYS A CG  1 
ATOM   181  C  CD  . LYS A 1 24  ? -8.574  -23.46  33.03   1   58.15  ? 20  LYS A CD  1 
ATOM   182  C  CE  . LYS A 1 24  ? -9.732  -24.249 33.577  1   61.12  ? 20  LYS A CE  1 
ATOM   183  N  NZ  . LYS A 1 24  ? -9.523  -25.691 33.708  1   59.74  ? 20  LYS A NZ  1 
ATOM   184  N  N   . ALA A 1 25  ? -10.105 -18.847 32.336  1   56.06  ? 21  ALA A N   1 
ATOM   185  C  CA  . ALA A 1 25  ? -10.702 -18.049 33.399  1   56.58  ? 21  ALA A CA  1 
ATOM   186  C  C   . ALA A 1 25  ? -12.056 -18.642 33.769  1   58.19  ? 21  ALA A C   1 
ATOM   187  O  O   . ALA A 1 25  ? -12.567 -19.523 33.075  1   62.29  ? 21  ALA A O   1 
ATOM   188  C  CB  . ALA A 1 25  ? -10.837 -16.609 32.965  1   50.93  ? 21  ALA A CB  1 
ATOM   189  N  N   . ARG A 1 26  ? -12.635 -18.127 34.847  1   57.13  ? 22  ARG A N   1 
ATOM   190  C  CA  . ARG A 1 26  ? -13.906 -18.629 35.326  1   59.94  ? 22  ARG A CA  1 
ATOM   191  C  C   . ARG A 1 26  ? -14.845 -17.443 35.539  1   60.43  ? 22  ARG A C   1 
ATOM   192  O  O   . ARG A 1 26  ? -14.437 -16.419 36.096  1   55.86  ? 22  ARG A O   1 
ATOM   193  C  CB  . ARG A 1 26  ? -13.618 -19.429 36.604  1   64.46  ? 22  ARG A CB  1 
ATOM   194  C  CG  . ARG A 1 26  ? -14.859 -19.929 37.326  1   77.24  ? 22  ARG A CG  1 
ATOM   195  C  CD  . ARG A 1 26  ? -14.448 -20.885 38.451  1   86.35  ? 22  ARG A CD  1 
ATOM   196  N  NE  . ARG A 1 26  ? -14.312 -20.062 39.661  1   108.86 ? 22  ARG A NE  1 
ATOM   197  C  CZ  . ARG A 1 26  ? -13.181 -19.625 40.225  1   108.09 ? 22  ARG A CZ  1 
ATOM   198  N  NH1 . ARG A 1 26  ? -12.016 -20.11  39.821  1   100.54 ? 22  ARG A NH1 1 
ATOM   199  N  NH2 . ARG A 1 26  ? -13.228 -18.703 41.18   1   98.63  ? 22  ARG A NH2 1 
ATOM   200  N  N   . ASN A 1 27  ? -16.094 -17.592 35.073  1   58.68  ? 23  ASN A N   1 
ATOM   201  C  CA  . ASN A 1 27  ? -17.139 -16.615 35.355  1   55.46  ? 23  ASN A CA  1 
ATOM   202  C  C   . ASN A 1 27  ? -17.566 -16.831 36.8    1   59.16  ? 23  ASN A C   1 
ATOM   203  O  O   . ASN A 1 27  ? -17.976 -17.927 37.167  1   65.48  ? 23  ASN A O   1 
ATOM   204  C  CB  . ASN A 1 27  ? -18.279 -16.726 34.347  1   47.92  ? 23  ASN A CB  1 
ATOM   205  C  CG  . ASN A 1 27  ? -19.338 -15.668 34.508  1   47.23  ? 23  ASN A CG  1 
ATOM   206  O  OD1 . ASN A 1 27  ? -19.726 -15.304 35.627  1   46.39  ? 23  ASN A OD1 1 
ATOM   207  N  ND2 . ASN A 1 27  ? -19.813 -15.172 33.381  1   44.67  ? 23  ASN A ND2 1 
ATOM   208  N  N   . LYS A 1 28  ? -17.424 -15.793 37.628  1   62.82  ? 24  LYS A N   1 
ATOM   209  C  CA  . LYS A 1 28  ? -17.67  -15.902 39.056  1   62.15  ? 24  LYS A CA  1 
ATOM   210  C  C   . LYS A 1 28  ? -19.168 -15.925 39.325  1   61.62  ? 24  LYS A C   1 
ATOM   211  O  O   . LYS A 1 28  ? -19.597 -16.315 40.399  1   62.63  ? 24  LYS A O   1 
ATOM   212  C  CB  . LYS A 1 28  ? -17.027 -14.715 39.771  1   68.17  ? 24  LYS A CB  1 
ATOM   213  C  CG  . LYS A 1 28  ? -15.508 -14.762 39.8    1   76.9   ? 24  LYS A CG  1 
ATOM   214  C  CD  . LYS A 1 28  ? -14.903 -13.605 40.603  1   85.3   ? 24  LYS A CD  1 
ATOM   215  C  CE  . LYS A 1 28  ? -14.466 -12.492 39.668  1   92.49  ? 24  LYS A CE  1 
ATOM   216  N  NZ  . LYS A 1 28  ? -13.95  -11.35  40.438  1   87.3   ? 24  LYS A NZ  1 
ATOM   217  N  N   . LEU A 1 29  ? -19.972 -15.523 38.337  1   62.01  ? 25  LEU A N   1 
ATOM   218  C  CA  . LEU A 1 29  ? -21.406 -15.432 38.564  1   61.03  ? 25  LEU A CA  1 
ATOM   219  C  C   . LEU A 1 29  ? -22.152 -16.665 38.043  1   60.08  ? 25  LEU A C   1 
ATOM   220  O  O   . LEU A 1 29  ? -23.104 -17.1   38.699  1   62.17  ? 25  LEU A O   1 
ATOM   221  C  CB  . LEU A 1 29  ? -21.903 -14.126 37.957  1   56.29  ? 25  LEU A CB  1 
ATOM   222  C  CG  . LEU A 1 29  ? -21.561 -12.875 38.771  1   56.14  ? 25  LEU A CG  1 
ATOM   223  C  CD1 . LEU A 1 29  ? -22.09  -11.658 38.068  1   56.36  ? 25  LEU A CD1 1 
ATOM   224  C  CD2 . LEU A 1 29  ? -22.122 -12.947 40.17   1   56.33  ? 25  LEU A CD2 1 
ATOM   225  N  N   . THR A 1 30  ? -21.704 -17.219 36.9    1   51.29  ? 26  THR A N   1 
ATOM   226  C  CA  . THR A 1 30  ? -22.393 -18.326 36.251  1   51.37  ? 26  THR A CA  1 
ATOM   227  C  C   . THR A 1 30  ? -21.673 -19.656 36.464  1   56.04  ? 26  THR A C   1 
ATOM   228  O  O   . THR A 1 30  ? -22.308 -20.711 36.396  1   58.61  ? 26  THR A O   1 
ATOM   229  C  CB  . THR A 1 30  ? -22.593 -18.075 34.76   1   46.16  ? 26  THR A CB  1 
ATOM   230  O  OG1 . THR A 1 30  ? -21.328 -17.97  34.119  1   46.9   ? 26  THR A OG1 1 
ATOM   231  C  CG2 . THR A 1 30  ? -23.377 -16.807 34.514  1   46.6   ? 26  THR A CG2 1 
ATOM   232  N  N   . GLY A 1 31  ? -20.348 -19.611 36.671  1   56.68  ? 27  GLY A N   1 
ATOM   233  C  CA  . GLY A 1 31  ? -19.547 -20.81  36.866  1   53.67  ? 27  GLY A CA  1 
ATOM   234  C  C   . GLY A 1 31  ? -18.747 -21.156 35.611  1   52.07  ? 27  GLY A C   1 
ATOM   235  O  O   . GLY A 1 31  ? -17.838 -21.987 35.657  1   54.07  ? 27  GLY A O   1 
ATOM   236  N  N   . GLU A 1 32  ? -19.091 -20.492 34.504  1   47.22  ? 28  GLU A N   1 
ATOM   237  C  CA  . GLU A 1 32  ? -18.603 -20.874 33.19   1   49.03  ? 28  GLU A CA  1 
ATOM   238  C  C   . GLU A 1 32  ? -17.082 -20.727 33.129  1   52.13  ? 28  GLU A C   1 
ATOM   239  O  O   . GLU A 1 32  ? -16.537 -19.685 33.504  1   55.58  ? 28  GLU A O   1 
ATOM   240  C  CB  . GLU A 1 32  ? -19.334 -20.08  32.102  1   45.91  ? 28  GLU A CB  1 
ATOM   241  C  CG  . GLU A 1 32  ? -18.98  -20.567 30.704  1   45.11  ? 28  GLU A CG  1 
ATOM   242  C  CD  . GLU A 1 32  ? -19.716 -19.882 29.567  1   51.61  ? 28  GLU A CD  1 
ATOM   243  O  OE1 . GLU A 1 32  ? -20.311 -18.777 29.76   1   49.3   ? 28  GLU A OE1 1 
ATOM   244  O  OE2 . GLU A 1 32  ? -19.693 -20.503 28.465  1   59.26  ? 28  GLU A OE2 1 
ATOM   245  N  N   . VAL A 1 33  ? -16.401 -21.798 32.698  1   51.27  ? 29  VAL A N   1 
ATOM   246  C  CA  . VAL A 1 33  ? -14.988 -21.719 32.365  1   49.23  ? 29  VAL A CA  1 
ATOM   247  C  C   . VAL A 1 33  ? -14.87  -21.2   30.939  1   48.94  ? 29  VAL A C   1 
ATOM   248  O  O   . VAL A 1 33  ? -15.553 -21.709 30.05   1   48.69  ? 29  VAL A O   1 
ATOM   249  C  CB  . VAL A 1 33  ? -14.301 -23.088 32.499  1   49.13  ? 29  VAL A CB  1 
ATOM   250  C  CG1 . VAL A 1 33  ? -12.823 -23.011 32.12   1   53.69  ? 29  VAL A CG1 1 
ATOM   251  C  CG2 . VAL A 1 33  ? -14.469 -23.651 33.898  1   48.47  ? 29  VAL A CG2 1 
ATOM   252  N  N   . VAL A 1 34  ? -13.99  -20.21  30.731  1   48.49  ? 30  VAL A N   1 
ATOM   253  C  CA  . VAL A 1 34  ? -13.792 -19.587 29.423  1   45.9   ? 30  VAL A CA  1 
ATOM   254  C  C   . VAL A 1 34  ? -12.292 -19.501 29.134  1   46.35  ? 30  VAL A C   1 
ATOM   255  O  O   . VAL A 1 34  ? -11.468 -19.757 30.014  1   51.85  ? 30  VAL A O   1 
ATOM   256  C  CB  . VAL A 1 34  ? -14.458 -18.189 29.365  1   45.9   ? 30  VAL A CB  1 
ATOM   257  C  CG1 . VAL A 1 34  ? -15.953 -18.265 29.651  1   44.6   ? 30  VAL A CG1 1 
ATOM   258  C  CG2 . VAL A 1 34  ? -13.819 -17.206 30.343  1   45.58  ? 30  VAL A CG2 1 
ATOM   259  N  N   . ALA A 1 35  ? -11.949 -19.178 27.892  1   45.91  ? 31  ALA A N   1 
ATOM   260  C  CA  . ALA A 1 35  ? -10.607 -18.766 27.525  1   47.75  ? 31  ALA A CA  1 
ATOM   261  C  C   . ALA A 1 35  ? -10.664 -17.273 27.216  1   49.24  ? 31  ALA A C   1 
ATOM   262  O  O   . ALA A 1 35  ? -11.48  -16.91  26.377  1   49.88  ? 31  ALA A O   1 
ATOM   263  C  CB  . ALA A 1 35  ? -10.172 -19.531 26.289  1   40.59  ? 31  ALA A CB  1 
ATOM   264  N  N   . LEU A 1 36  ? -9.838  -16.44  27.877  1   47.32  ? 32  LEU A N   1 
ATOM   265  C  CA  . LEU A 1 36  ? -9.714  -15.032 27.535  1   48.14  ? 32  LEU A CA  1 
ATOM   266  C  C   . LEU A 1 36  ? -8.499  -14.805 26.63   1   52.52  ? 32  LEU A C   1 
ATOM   267  O  O   . LEU A 1 36  ? -7.388  -15.029 27.068  1   60.4   ? 32  LEU A O   1 
ATOM   268  C  CB  . LEU A 1 36  ? -9.579  -14.239 28.824  1   50.83  ? 32  LEU A CB  1 
ATOM   269  C  CG  . LEU A 1 36  ? -10.723 -14.365 29.83   1   56.03  ? 32  LEU A CG  1 
ATOM   270  C  CD1 . LEU A 1 36  ? -10.315 -13.723 31.135  1   54.84  ? 32  LEU A CD1 1 
ATOM   271  C  CD2 . LEU A 1 36  ? -12.018 -13.728 29.374  1   57.85  ? 32  LEU A CD2 1 
ATOM   272  N  N   . LYS A 1 37  ? -8.705  -14.403 25.366  1   51.22  ? 33  LYS A N   1 
ATOM   273  C  CA  . LYS A 1 37  ? -7.64   -13.902 24.51   1   57.41  ? 33  LYS A CA  1 
ATOM   274  C  C   . LYS A 1 37  ? -7.569  -12.392 24.732  1   65.16  ? 33  LYS A C   1 
ATOM   275  O  O   . LYS A 1 37  ? -8.561  -11.697 24.543  1   73.7   ? 33  LYS A O   1 
ATOM   276  C  CB  . LYS A 1 37  ? -7.861  -14.258 23.027  1   59.31  ? 33  LYS A CB  1 
ATOM   277  C  CG  . LYS A 1 37  ? -6.713  -13.954 22.073  1   58.59  ? 33  LYS A CG  1 
ATOM   278  C  CD  . LYS A 1 37  ? -6.975  -14.202 20.59   1   69.8   ? 33  LYS A CD  1 
ATOM   279  C  CE  . LYS A 1 37  ? -7.2    -15.631 20.197  1   79.23  ? 33  LYS A CE  1 
ATOM   280  N  NZ  . LYS A 1 37  ? -7.057  -15.879 18.757  1   73.45  ? 33  LYS A NZ  1 
ATOM   281  N  N   . LYS A 1 38  ? -6.414  -11.907 25.204  1   70.42  ? 34  LYS A N   1 
ATOM   282  C  CA  . LYS A 1 38  ? -6.124  -10.489 25.313  1   71.31  ? 34  LYS A CA  1 
ATOM   283  C  C   . LYS A 1 38  ? -5.413  -10.034 24.041  1   80.71  ? 34  LYS A C   1 
ATOM   284  O  O   . LYS A 1 38  ? -4.451  -10.681 23.622  1   88.04  ? 34  LYS A O   1 
ATOM   285  C  CB  . LYS A 1 38  ? -5.212  -10.245 26.516  1   76.28  ? 34  LYS A CB  1 
ATOM   286  C  CG  . LYS A 1 38  ? -4.99   -8.766  26.837  1   87.87  ? 34  LYS A CG  1 
ATOM   287  C  CD  . LYS A 1 38  ? -4.251  -8.52   28.148  1   96.05  ? 34  LYS A CD  1 
ATOM   288  C  CE  . LYS A 1 38  ? -2.806  -8.912  28.106  1   105.3  ? 34  LYS A CE  1 
ATOM   289  N  NZ  . LYS A 1 38  ? -2.156  -8.806  29.415  1   111.08 ? 34  LYS A NZ  1 
ATOM   290  N  N   . ILE A 1 39  ? -5.937  -8.961  23.427  1   81.14  ? 35  ILE A N   1 
ATOM   291  C  CA  . ILE A 1 39  ? -5.331  -8.247  22.315  1   76.61  ? 35  ILE A CA  1 
ATOM   292  C  C   . ILE A 1 39  ? -5.042  -6.836  22.824  1   81.38  ? 35  ILE A C   1 
ATOM   293  O  O   . ILE A 1 39  ? -5.951  -6.148  23.281  1   91.18  ? 35  ILE A O   1 
ATOM   294  C  CB  . ILE A 1 39  ? -6.28   -8.298  21.095  1   75.44  ? 35  ILE A CB  1 
ATOM   295  C  CG1 . ILE A 1 39  ? -6.263  -9.708  20.448  1   71.69  ? 35  ILE A CG1 1 
ATOM   296  C  CG2 . ILE A 1 39  ? -5.964  -7.213  20.058  1   70.7   ? 35  ILE A CG2 1 
ATOM   297  C  CD1 . ILE A 1 39  ? -7.597  -10.16  19.88   1   63.71  ? 35  ILE A CD1 1 
ATOM   298  N  N   . ARG A 1 40  ? -3.768  -6.424  22.814  1   92.46  ? 36  ARG A N   1 
ATOM   299  C  CA  . ARG A 1 40  ? -3.399  -5.123  23.361  1   104.44 ? 36  ARG A CA  1 
ATOM   300  C  C   . ARG A 1 40  ? -3.356  -4.064  22.26   1   105.89 ? 36  ARG A C   1 
ATOM   301  O  O   . ARG A 1 40  ? -2.709  -4.279  21.232  1   103.04 ? 36  ARG A O   1 
ATOM   302  C  CB  . ARG A 1 40  ? -2.085  -5.167  24.15   1   113.8  ? 36  ARG A CB  1 
ATOM   303  C  CG  . ARG A 1 40  ? -2.221  -4.804  25.623  1   130.71 ? 36  ARG A CG  1 
ATOM   304  C  CD  . ARG A 1 40  ? -0.87   -4.647  26.306  1   140.12 ? 36  ARG A CD  1 
ATOM   305  N  NE  . ARG A 1 40  ? -0.293  -5.987  26.466  1   145.66 ? 36  ARG A NE  1 
ATOM   306  C  CZ  . ARG A 1 40  ? -0.298  -6.7    27.586  1   144.57 ? 36  ARG A CZ  1 
ATOM   307  N  NH1 . ARG A 1 40  ? 0.165   -7.94   27.568  1   137.56 ? 36  ARG A NH1 1 
ATOM   308  N  NH2 . ARG A 1 40  ? -0.789  -6.18   28.701  1   140.13 ? 36  ARG A NH2 1 
ATOM   309  N  N   . LEU A 1 41  ? -4.05   -2.936  22.492  1   103.08 ? 37  LEU A N   1 
ATOM   310  C  CA  . LEU A 1 41  ? -4.188  -1.869  21.511  1   102.47 ? 37  LEU A CA  1 
ATOM   311  C  C   . LEU A 1 41  ? -3.331  -0.676  21.92   1   128.74 ? 37  LEU A C   1 
ATOM   312  O  O   . LEU A 1 41  ? -2.783  0.003   21.056  1   133.55 ? 37  LEU A O   1 
ATOM   313  C  CB  . LEU A 1 41  ? -5.647  -1.435  21.395  1   85.3   ? 37  LEU A CB  1 
ATOM   314  C  CG  . LEU A 1 41  ? -6.681  -2.553  21.349  1   77.88  ? 37  LEU A CG  1 
ATOM   315  C  CD1 . LEU A 1 41  ? -8.023  -2.019  21.82   1   73.88  ? 37  LEU A CD1 1 
ATOM   316  C  CD2 . LEU A 1 41  ? -6.728  -3.084  19.939  1   75.79  ? 37  LEU A CD2 1 
ATOM   317  N  N   . ASP A 1 42  ? -3.282  -0.383  23.229  1   162.28 ? 38  ASP A N   1 
ATOM   318  C  CA  . ASP A 1 42  ? -2.443  0.669   23.801  1   168.65 ? 38  ASP A CA  1 
ATOM   319  C  C   . ASP A 1 42  ? -1.029  0.616   23.205  1   162.68 ? 38  ASP A C   1 
ATOM   320  O  O   . ASP A 1 42  ? -0.462  1.654   22.865  1   145.62 ? 38  ASP A O   1 
ATOM   321  C  CB  . ASP A 1 42  ? -2.448  0.581   25.322  1   176.42 ? 38  ASP A CB  1 
ATOM   322  C  CG  . ASP A 1 42  ? -2.131  -0.807  25.866  1   182.96 ? 38  ASP A CG  1 
ATOM   323  O  OD1 . ASP A 1 42  ? -2.03   -1.759  25.041  1   196    ? 38  ASP A OD1 1 
ATOM   324  O  OD2 . ASP A 1 42  ? -1.971  -0.934  27.099  1   170.36 ? 38  ASP A OD2 1 
ATOM   325  N  N   . THR A 1 43  ? -0.479  -0.604  23.084  1   162.39 ? 39  THR A N   1 
ATOM   326  C  CA  . THR A 1 43  ? 0.8     -0.886  22.435  1   158.4  ? 39  THR A CA  1 
ATOM   327  C  C   . THR A 1 43  ? 0.704   -0.732  20.916  1   171.73 ? 39  THR A C   1 
ATOM   328  O  O   . THR A 1 43  ? 1.736   -0.687  20.252  1   175.29 ? 39  THR A O   1 
ATOM   329  C  CB  . THR A 1 43  ? 1.291   -2.289  22.799  1   145.97 ? 39  THR A CB  1 
ATOM   330  O  OG1 . THR A 1 43  ? 0.328   -3.262  22.395  1   136.27 ? 39  THR A OG1 1 
ATOM   331  C  CG2 . THR A 1 43  ? 1.411   -2.484  24.294  1   137.13 ? 39  THR A CG2 1 
ATOM   332  N  N   . GLU A 1 44  ? -0.521  -0.709  20.371  1   174.95 ? 40  GLU A N   1 
ATOM   333  C  CA  . GLU A 1 44  ? -0.754  -0.643  18.931  1   158.93 ? 40  GLU A CA  1 
ATOM   334  C  C   . GLU A 1 44  ? -0.741  0.8     18.422  1   151    ? 40  GLU A C   1 
ATOM   335  O  O   . GLU A 1 44  ? -1.444  1.669   18.944  1   147.1  ? 40  GLU A O   1 
ATOM   336  C  CB  . GLU A 1 44  ? -2.062  -1.332  18.536  1   156.09 ? 40  GLU A CB  1 
ATOM   337  C  CG  . GLU A 1 44  ? -2.014  -2.851  18.658  1   159.84 ? 40  GLU A CG  1 
ATOM   338  C  CD  . GLU A 1 44  ? -0.654  -3.439  18.349  1   162.64 ? 40  GLU A CD  1 
ATOM   339  O  OE1 . GLU A 1 44  ? -0.278  -3.494  17.151  1   151.22 ? 40  GLU A OE1 1 
ATOM   340  O  OE2 . GLU A 1 44  ? 0.041   -3.786  19.339  1   171.25 ? 40  GLU A OE2 1 
ATOM   341  N  N   . THR A 1 45  ? 0.041   1.02    17.356  1   142.31 ? 41  THR A N   1 
ATOM   342  C  CA  . THR A 1 45  ? 0.142   2.296   16.662  1   134.62 ? 41  THR A CA  1 
ATOM   343  C  C   . THR A 1 45  ? -0.773  2.313   15.43   1   119.26 ? 41  THR A C   1 
ATOM   344  O  O   . THR A 1 45  ? -0.999  3.371   14.84   1   112.36 ? 41  THR A O   1 
ATOM   345  C  CB  . THR A 1 45  ? 1.608   2.581   16.315  1   140.75 ? 41  THR A CB  1 
ATOM   346  O  OG1 . THR A 1 45  ? 1.972   1.468   15.503  1   152.89 ? 41  THR A OG1 1 
ATOM   347  C  CG2 . THR A 1 45  ? 2.529   2.664   17.527  1   129.72 ? 41  THR A CG2 1 
ATOM   348  N  N   . GLU A 1 46  ? -1.272  1.133   15.031  1   93.98  ? 42  GLU A N   1 
ATOM   349  C  CA  . GLU A 1 46  ? -2.024  1.003   13.8    1   84.61  ? 42  GLU A CA  1 
ATOM   350  C  C   . GLU A 1 46  ? -3.478  0.702   14.147  1   74.73  ? 42  GLU A C   1 
ATOM   351  O  O   . GLU A 1 46  ? -4.243  0.239   13.297  1   71.98  ? 42  GLU A O   1 
ATOM   352  C  CB  . GLU A 1 46  ? -1.318  -0.007  12.897  1   94.3   ? 42  GLU A CB  1 
ATOM   353  C  CG  . GLU A 1 46  ? -0.076  0.561   12.206  1   101.8  ? 42  GLU A CG  1 
ATOM   354  C  CD  . GLU A 1 46  ? -0.318  1.593   11.107  1   104.23 ? 42  GLU A CD  1 
ATOM   355  O  OE1 . GLU A 1 46  ? -1.068  1.285   10.154  1   98.95  ? 42  GLU A OE1 1 
ATOM   356  O  OE2 . GLU A 1 46  ? 0.233   2.714   11.2    1   99.32  ? 42  GLU A OE2 1 
ATOM   357  N  N   . GLY A 1 47  ? -3.844  1.017   15.396  1   70.49  ? 43  GLY A N   1 
ATOM   358  C  CA  . GLY A 1 47  ? -5.186  0.82    15.921  1   64.1   ? 43  GLY A CA  1 
ATOM   359  C  C   . GLY A 1 47  ? -5.508  -0.661  16.117  1   57.49  ? 43  GLY A C   1 
ATOM   360  O  O   . GLY A 1 47  ? -4.645  -1.464  16.472  1   58.96  ? 43  GLY A O   1 
ATOM   361  N  N   . VAL A 1 48  ? -6.766  -1.024  15.889  1   51.48  ? 44  VAL A N   1 
ATOM   362  C  CA  . VAL A 1 48  ? -7.154  -2.406  16.079  1   49.38  ? 44  VAL A CA  1 
ATOM   363  C  C   . VAL A 1 48  ? -6.595  -3.237  14.924  1   52.21  ? 44  VAL A C   1 
ATOM   364  O  O   . VAL A 1 48  ? -6.801  -2.914  13.749  1   51.2   ? 44  VAL A O   1 
ATOM   365  C  CB  . VAL A 1 48  ? -8.679  -2.546  16.219  1   45.48  ? 44  VAL A CB  1 
ATOM   366  C  CG1 . VAL A 1 48  ? -9.101  -3.986  16.505  1   41.63  ? 44  VAL A CG1 1 
ATOM   367  C  CG2 . VAL A 1 48  ? -9.187  -1.614  17.297  1   46.22  ? 44  VAL A CG2 1 
ATOM   368  N  N   . PRO A 1 49  ? -5.859  -4.331  15.223  1   54.98  ? 45  PRO A N   1 
ATOM   369  C  CA  . PRO A 1 49  ? -5.234  -5.148  14.182  1   52.88  ? 45  PRO A CA  1 
ATOM   370  C  C   . PRO A 1 49  ? -6.307  -5.746  13.283  1   54.32  ? 45  PRO A C   1 
ATOM   371  O  O   . PRO A 1 49  ? -7.378  -6.097  13.766  1   55.15  ? 45  PRO A O   1 
ATOM   372  C  CB  . PRO A 1 49  ? -4.503  -6.258  14.976  1   49.41  ? 45  PRO A CB  1 
ATOM   373  C  CG  . PRO A 1 49  ? -4.38   -5.719  16.352  1   51.63  ? 45  PRO A CG  1 
ATOM   374  C  CD  . PRO A 1 49  ? -5.602  -4.84   16.58   1   54.49  ? 45  PRO A CD  1 
ATOM   375  N  N   . SER A 1 50  ? -5.976  -5.931  11.997  1   56.42  ? 46  SER A N   1 
ATOM   376  C  CA  . SER A 1 50  ? -6.87   -6.536  11.018  1   51.01  ? 46  SER A CA  1 
ATOM   377  C  C   . SER A 1 50  ? -7.153  -7.985  11.374  1   50.93  ? 46  SER A C   1 
ATOM   378  O  O   . SER A 1 50  ? -8.241  -8.508  11.123  1   54.88  ? 46  SER A O   1 
ATOM   379  C  CB  . SER A 1 50  ? -6.329  -6.432  9.623   1   48.84  ? 46  SER A CB  1 
ATOM   380  O  OG  . SER A 1 50  ? -5.009  -6.944  9.528   1   57.71  ? 46  SER A OG  1 
ATOM   381  N  N   . THR A 1 51  ? -6.148  -8.642  11.943  1   52.39  ? 47  THR A N   1 
ATOM   382  C  CA  . THR A 1 51  ? -6.291  -10.036 12.321  1   50.07  ? 47  THR A CA  1 
ATOM   383  C  C   . THR A 1 51  ? -7.461  -10.176 13.301  1   43.77  ? 47  THR A C   1 
ATOM   384  O  O   . THR A 1 51  ? -8.314  -11.034 13.127  1   45.29  ? 47  THR A O   1 
ATOM   385  C  CB  . THR A 1 51  ? -4.933  -10.528 12.816  1   51.28  ? 47  THR A CB  1 
ATOM   386  O  OG1 . THR A 1 51  ? -5.159  -11.897 13.11   1   61.81  ? 47  THR A OG1 1 
ATOM   387  C  CG2 . THR A 1 51  ? -4.479  -9.786  14.057  1   54.25  ? 47  THR A CG2 1 
ATOM   388  N  N   . ALA A 1 52  ? -7.56   -9.257  14.26   1   44.22  ? 48  ALA A N   1 
ATOM   389  C  CA  . ALA A 1 52  ? -8.597  -9.274  15.28   1   44.34  ? 48  ALA A CA  1 
ATOM   390  C  C   . ALA A 1 52  ? -9.952  -8.875  14.681  1   49.37  ? 48  ALA A C   1 
ATOM   391  O  O   . ALA A 1 52  ? -10.975 -9.462  15.053  1   49.97  ? 48  ALA A O   1 
ATOM   392  C  CB  . ALA A 1 52  ? -8.202  -8.386  16.471  1   39.01  ? 48  ALA A CB  1 
ATOM   393  N  N   . ILE A 1 53  ? -9.951  -7.873  13.776  1   46.71  ? 49  ILE A N   1 
ATOM   394  C  CA  . ILE A 1 53  ? -11.16  -7.398  13.119  1   45.47  ? 49  ILE A CA  1 
ATOM   395  C  C   . ILE A 1 53  ? -11.801 -8.545  12.342  1   44.15  ? 49  ILE A C   1 
ATOM   396  O  O   . ILE A 1 53  ? -13.015 -8.699  12.348  1   43.06  ? 49  ILE A O   1 
ATOM   397  C  CB  . ILE A 1 53  ? -10.856 -6.181  12.227  1   45.28  ? 49  ILE A CB  1 
ATOM   398  C  CG1 . ILE A 1 53  ? -10.786 -4.929  13.097  1   47.09  ? 49  ILE A CG1 1 
ATOM   399  C  CG2 . ILE A 1 53  ? -11.919 -6.038  11.141  1   41.01  ? 49  ILE A CG2 1 
ATOM   400  C  CD1 . ILE A 1 53  ? -10.257 -3.696  12.401  1   47.56  ? 49  ILE A CD1 1 
ATOM   401  N  N   . ARG A 1 54  ? -10.964 -9.345  11.686  1   44.77  ? 50  ARG A N   1 
ATOM   402  C  CA  . ARG A 1 54  ? -11.451 -10.485 10.931  1   46.4   ? 50  ARG A CA  1 
ATOM   403  C  C   . ARG A 1 54  ? -11.928 -11.576 11.886  1   45.49  ? 50  ARG A C   1 
ATOM   404  O  O   . ARG A 1 54  ? -12.998 -12.154 11.711  1   46.74  ? 50  ARG A O   1 
ATOM   405  C  CB  . ARG A 1 54  ? -10.354 -10.999 9.992   1   43.41  ? 50  ARG A CB  1 
ATOM   406  C  CG  . ARG A 1 54  ? -10.184 -10.111 8.768   1   44.45  ? 50  ARG A CG  1 
ATOM   407  C  CD  . ARG A 1 54  ? -9.152  -10.679 7.825   1   42.35  ? 50  ARG A CD  1 
ATOM   408  N  NE  . ARG A 1 54  ? -9.017  -9.883  6.606   1   43.05  ? 50  ARG A NE  1 
ATOM   409  C  CZ  . ARG A 1 54  ? -7.999  -10.029 5.766   1   44.32  ? 50  ARG A CZ  1 
ATOM   410  N  NH1 . ARG A 1 54  ? -7.081  -10.952 5.982   1   40.46  ? 50  ARG A NH1 1 
ATOM   411  N  NH2 . ARG A 1 54  ? -7.892  -9.235  4.721   1   41.1   ? 50  ARG A NH2 1 
ATOM   412  N  N   . GLU A 1 55  ? -11.125 -11.866 12.906  1   48.81  ? 51  GLU A N   1 
ATOM   413  C  CA  . GLU A 1 55  ? -11.481 -12.945 13.819  1   47.8   ? 51  GLU A CA  1 
ATOM   414  C  C   . GLU A 1 55  ? -12.838 -12.668 14.469  1   42.5   ? 51  GLU A C   1 
ATOM   415  O  O   . GLU A 1 55  ? -13.711 -13.521 14.442  1   39.84  ? 51  GLU A O   1 
ATOM   416  C  CB  . GLU A 1 55  ? -10.371 -13.197 14.835  1   47.61  ? 51  GLU A CB  1 
ATOM   417  C  CG  . GLU A 1 55  ? -10.806 -14.251 15.84   1   53.74  ? 51  GLU A CG  1 
ATOM   418  C  CD  . GLU A 1 55  ? -9.641  -14.83  16.603  1   61.38  ? 51  GLU A CD  1 
ATOM   419  O  OE1 . GLU A 1 55  ? -8.709  -14.059 16.904  1   57.44  ? 51  GLU A OE1 1 
ATOM   420  O  OE2 . GLU A 1 55  ? -9.695  -16.06  16.887  1   82.81  ? 51  GLU A OE2 1 
ATOM   421  N  N   . ILE A 1 56  ? -13.02  -11.455 15.006  1   42.96  ? 52  ILE A N   1 
ATOM   422  C  CA  . ILE A 1 56  ? -14.245 -11.119 15.705  1   43.36  ? 52  ILE A CA  1 
ATOM   423  C  C   . ILE A 1 56  ? -15.408 -11.105 14.719  1   46.66  ? 52  ILE A C   1 
ATOM   424  O  O   . ILE A 1 56  ? -16.383 -11.831 14.945  1   49.94  ? 52  ILE A O   1 
ATOM   425  C  CB  . ILE A 1 56  ? -14.149 -9.793  16.48   1   43.9   ? 52  ILE A CB  1 
ATOM   426  C  CG1 . ILE A 1 56  ? -13.067 -9.82   17.558  1   42.45  ? 52  ILE A CG1 1 
ATOM   427  C  CG2 . ILE A 1 56  ? -15.515 -9.422  17.058  1   40.98  ? 52  ILE A CG2 1 
ATOM   428  C  CD1 . ILE A 1 56  ? -12.629 -8.441  18.026  1   41.3   ? 52  ILE A CD1 1 
ATOM   429  N  N   . SER A 1 57  ? -15.314 -10.283 13.655  1   42.77  ? 53  SER A N   1 
ATOM   430  C  CA  . SER A 1 57  ? -16.441 -10.14  12.729  1   46.45  ? 53  SER A CA  1 
ATOM   431  C  C   . SER A 1 57  ? -16.873 -11.495 12.145  1   47.07  ? 53  SER A C   1 
ATOM   432  O  O   . SER A 1 57  ? -18.069 -11.782 12.046  1   51.2   ? 53  SER A O   1 
ATOM   433  C  CB  . SER A 1 57  ? -16.206 -9.109  11.639  1   43.14  ? 53  SER A CB  1 
ATOM   434  O  OG  . SER A 1 57  ? -15.107 -9.497  10.824  1   45.96  ? 53  SER A OG  1 
ATOM   435  N  N   . LEU A 1 58  ? -15.904 -12.355 11.821  1   43.11  ? 54  LEU A N   1 
ATOM   436  C  CA  . LEU A 1 58  ? -16.229 -13.613 11.184  1   40.63  ? 54  LEU A CA  1 
ATOM   437  C  C   . LEU A 1 58  ? -16.795 -14.601 12.188  1   45.14  ? 54  LEU A C   1 
ATOM   438  O  O   . LEU A 1 58  ? -17.735 -15.322 11.852  1   51.1   ? 54  LEU A O   1 
ATOM   439  C  CB  . LEU A 1 58  ? -15.054 -14.187 10.421  1   35.64  ? 54  LEU A CB  1 
ATOM   440  C  CG  . LEU A 1 58  ? -14.545 -13.277 9.302   1   41.11  ? 54  LEU A CG  1 
ATOM   441  C  CD1 . LEU A 1 58  ? -13.36  -13.899 8.59    1   38.94  ? 54  LEU A CD1 1 
ATOM   442  C  CD2 . LEU A 1 58  ? -15.66  -12.927 8.355   1   37.99  ? 54  LEU A CD2 1 
ATOM   443  N  N   . LEU A 1 59  ? -16.249 -14.614 13.409  1   48.45  ? 55  LEU A N   1 
ATOM   444  C  CA  . LEU A 1 59  ? -16.649 -15.594 14.414  1   47.96  ? 55  LEU A CA  1 
ATOM   445  C  C   . LEU A 1 59  ? -18.026 -15.275 14.994  1   52.95  ? 55  LEU A C   1 
ATOM   446  O  O   . LEU A 1 59  ? -18.724 -16.187 15.423  1   58.75  ? 55  LEU A O   1 
ATOM   447  C  CB  . LEU A 1 59  ? -15.614 -15.723 15.524  1   42.1   ? 55  LEU A CB  1 
ATOM   448  C  CG  . LEU A 1 59  ? -14.535 -16.777 15.31   1   42.96  ? 55  LEU A CG  1 
ATOM   449  C  CD1 . LEU A 1 59  ? -13.688 -16.85  16.568  1   41.82  ? 55  LEU A CD1 1 
ATOM   450  C  CD2 . LEU A 1 59  ? -15.166 -18.121 14.965  1   41.66  ? 55  LEU A CD2 1 
ATOM   451  N  N   . LYS A 1 60  ? -18.409 -13.988 14.998  1   61.89  ? 56  LYS A N   1 
ATOM   452  C  CA  . LYS A 1 60  ? -19.719 -13.538 15.45   1   64.66  ? 56  LYS A CA  1 
ATOM   453  C  C   . LYS A 1 60  ? -20.822 -14.258 14.677  1   62.56  ? 56  LYS A C   1 
ATOM   454  O  O   . LYS A 1 60  ? -21.874 -14.551 15.235  1   66.78  ? 56  LYS A O   1 
ATOM   455  C  CB  . LYS A 1 60  ? -19.893 -12.019 15.3    1   61.64  ? 56  LYS A CB  1 
ATOM   456  C  CG  . LYS A 1 60  ? -19.376 -11.2   16.466  1   63.55  ? 56  LYS A CG  1 
ATOM   457  C  CD  . LYS A 1 60  ? -20.037 -9.842  16.66   1   73.2   ? 56  LYS A CD  1 
ATOM   458  C  CE  . LYS A 1 60  ? -21.495 -9.935  17.016  1   80.06  ? 56  LYS A CE  1 
ATOM   459  N  NZ  . LYS A 1 60  ? -22.014 -8.664  17.535  1   77.33  ? 56  LYS A NZ  1 
ATOM   460  N  N   . GLU A 1 61  ? -20.554 -14.546 13.401  1   64.02  ? 57  GLU A N   1 
ATOM   461  C  CA  . GLU A 1 61  ? -21.541 -15.106 12.489  1   71.13  ? 57  GLU A CA  1 
ATOM   462  C  C   . GLU A 1 61  ? -21.531 -16.641 12.484  1   64.09  ? 57  GLU A C   1 
ATOM   463  O  O   . GLU A 1 61  ? -22.49  -17.273 12.04   1   67.62  ? 57  GLU A O   1 
ATOM   464  C  CB  . GLU A 1 61  ? -21.252 -14.556 11.092  1   84.55  ? 57  GLU A CB  1 
ATOM   465  C  CG  . GLU A 1 61  ? -21.418 -13.04  10.985  1   105.69 ? 57  GLU A CG  1 
ATOM   466  C  CD  . GLU A 1 61  ? -21.508 -12.451 9.576   1   108.7  ? 57  GLU A CD  1 
ATOM   467  O  OE1 . GLU A 1 61  ? -21.245 -13.201 8.608   1   87.53  ? 57  GLU A OE1 1 
ATOM   468  O  OE2 . GLU A 1 61  ? -21.872 -11.253 9.427   1   132.64 ? 57  GLU A OE2 1 
ATOM   469  N  N   . LEU A 1 62  ? -20.452 -17.253 12.974  1   53.4   ? 58  LEU A N   1 
ATOM   470  C  CA  . LEU A 1 62  ? -20.292 -18.687 12.829  1   50.2   ? 58  LEU A CA  1 
ATOM   471  C  C   . LEU A 1 62  ? -20.707 -19.42  14.103  1   47.94  ? 58  LEU A C   1 
ATOM   472  O  O   . LEU A 1 62  ? -19.842 -19.863 14.838  1   57.46  ? 58  LEU A O   1 
ATOM   473  C  CB  . LEU A 1 62  ? -18.832 -18.972 12.471  1   42.37  ? 58  LEU A CB  1 
ATOM   474  C  CG  . LEU A 1 62  ? -18.362 -18.425 11.12   1   44.69  ? 58  LEU A CG  1 
ATOM   475  C  CD1 . LEU A 1 62  ? -16.877 -18.618 10.945  1   39.48  ? 58  LEU A CD1 1 
ATOM   476  C  CD2 . LEU A 1 62  ? -19.116 -18.957 9.9     1   43.02  ? 58  LEU A CD2 1 
ATOM   477  N  N   . ASN A 1 63  ? -22.008 -19.608 14.344  1   48.39  ? 59  ASN A N   1 
ATOM   478  C  CA  . ASN A 1 63  ? -22.458 -20.462 15.44   1   51.85  ? 59  ASN A CA  1 
ATOM   479  C  C   . ASN A 1 63  ? -22.614 -21.891 14.923  1   49.76  ? 59  ASN A C   1 
ATOM   480  O  O   . ASN A 1 63  ? -23.491 -22.181 14.107  1   50.76  ? 59  ASN A O   1 
ATOM   481  C  CB  . ASN A 1 63  ? -23.716 -19.932 16.128  1   59.76  ? 59  ASN A CB  1 
ATOM   482  C  CG  . ASN A 1 63  ? -23.5   -18.504 16.573  1   88.51  ? 59  ASN A CG  1 
ATOM   483  O  OD1 . ASN A 1 63  ? -24.1   -17.576 16.017  1   96.92  ? 59  ASN A OD1 1 
ATOM   484  N  ND2 . ASN A 1 63  ? -22.611 -18.29  17.537  1   95.37  ? 59  ASN A ND2 1 
ATOM   485  N  N   . HIS A 1 64  ? -21.731 -22.777 15.382  1   41.79  ? 60  HIS A N   1 
ATOM   486  C  CA  . HIS A 1 64  ? -21.811 -24.165 14.987  1   40.66  ? 60  HIS A CA  1 
ATOM   487  C  C   . HIS A 1 64  ? -21.115 -25.004 16.053  1   41.37  ? 60  HIS A C   1 
ATOM   488  O  O   . HIS A 1 64  ? -20.104 -24.605 16.631  1   41.72  ? 60  HIS A O   1 
ATOM   489  C  CB  . HIS A 1 64  ? -21.188 -24.311 13.593  1   42.07  ? 60  HIS A CB  1 
ATOM   490  C  CG  . HIS A 1 64  ? -21.314 -25.68  13.057  1   45.02  ? 60  HIS A CG  1 
ATOM   491  N  ND1 . HIS A 1 64  ? -20.493 -26.711 13.471  1   45.03  ? 60  HIS A ND1 1 
ATOM   492  C  CD2 . HIS A 1 64  ? -22.181 -26.201 12.173  1   43.46  ? 60  HIS A CD2 1 
ATOM   493  C  CE1 . HIS A 1 64  ? -20.853 -27.818 12.837  1   48     ? 60  HIS A CE1 1 
ATOM   494  N  NE2 . HIS A 1 64  ? -21.873 -27.528 12.044  1   44.06  ? 60  HIS A NE2 1 
ATOM   495  N  N   . PRO A 1 65  ? -21.61  -26.219 16.346  1   44.65  ? 61  PRO A N   1 
ATOM   496  C  CA  . PRO A 1 65  ? -21.001 -27.014 17.418  1   42.27  ? 61  PRO A CA  1 
ATOM   497  C  C   . PRO A 1 65  ? -19.536 -27.398 17.191  1   41.88  ? 61  PRO A C   1 
ATOM   498  O  O   . PRO A 1 65  ? -18.844 -27.722 18.144  1   45.41  ? 61  PRO A O   1 
ATOM   499  C  CB  . PRO A 1 65  ? -21.943 -28.209 17.642  1   39.25  ? 61  PRO A CB  1 
ATOM   500  C  CG  . PRO A 1 65  ? -22.882 -28.201 16.446  1   43.28  ? 61  PRO A CG  1 
ATOM   501  C  CD  . PRO A 1 65  ? -22.78  -26.854 15.718  1   41.18  ? 61  PRO A CD  1 
ATOM   502  N  N   . ASN A 1 66  ? -19.043 -27.314 15.947  1   36.26  ? 62  ASN A N   1 
ATOM   503  C  CA  . ASN A 1 66  ? -17.661 -27.669 15.683  1   35.03  ? 62  ASN A CA  1 
ATOM   504  C  C   . ASN A 1 66  ? -16.841 -26.438 15.309  1   38.52  ? 62  ASN A C   1 
ATOM   505  O  O   . ASN A 1 66  ? -15.796 -26.548 14.673  1   42.92  ? 62  ASN A O   1 
ATOM   506  C  CB  . ASN A 1 66  ? -17.593 -28.755 14.616  1   36.22  ? 62  ASN A CB  1 
ATOM   507  C  CG  . ASN A 1 66  ? -18.344 -29.975 15.092  1   41.74  ? 62  ASN A CG  1 
ATOM   508  O  OD1 . ASN A 1 66  ? -19.408 -30.295 14.552  1   42.94  ? 62  ASN A OD1 1 
ATOM   509  N  ND2 . ASN A 1 66  ? -17.879 -30.606 16.163  1   39.42  ? 62  ASN A ND2 1 
ATOM   510  N  N   . ILE A 1 67  ? -17.31  -25.29  15.77   1   38.79  ? 63  ILE A N   1 
ATOM   511  C  CA  . ILE A 1 67  ? -16.519 -24.049 15.621  1   38.33  ? 63  ILE A CA  1 
ATOM   512  C  C   . ILE A 1 67  ? -16.494 -23.458 17.034  1   40.53  ? 63  ILE A C   1 
ATOM   513  O  O   . ILE A 1 67  ? -17.574 -23.316 17.615  1   49.64  ? 63  ILE A O   1 
ATOM   514  C  CB  . ILE A 1 67  ? -17.137 -23.098 14.583  1   40.89  ? 63  ILE A CB  1 
ATOM   515  C  CG1 . ILE A 1 67  ? -17.179 -23.723 13.193  1   40.31  ? 63  ILE A CG1 1 
ATOM   516  C  CG2 . ILE A 1 67  ? -16.408 -21.756 14.571  1   40.66  ? 63  ILE A CG2 1 
ATOM   517  C  CD1 . ILE A 1 67  ? -17.996 -22.933 12.189  1   39.55  ? 63  ILE A CD1 1 
ATOM   518  N  N   . VAL A 1 68  ? -15.312 -23.196 17.584  1   42.01  ? 64  VAL A N   1 
ATOM   519  C  CA  . VAL A 1 68  ? -15.193 -22.538 18.919  1   43.27  ? 64  VAL A CA  1 
ATOM   520  C  C   . VAL A 1 68  ? -16.103 -21.302 18.945  1   42.89  ? 64  VAL A C   1 
ATOM   521  O  O   . VAL A 1 68  ? -16.176 -20.582 17.936  1   41.39  ? 64  VAL A O   1 
ATOM   522  C  CB  . VAL A 1 68  ? -13.739 -22.184 19.298  1   46.26  ? 64  VAL A CB  1 
ATOM   523  C  CG1 . VAL A 1 68  ? -13.13  -21.139 18.37   1   46.21  ? 64  VAL A CG1 1 
ATOM   524  C  CG2 . VAL A 1 68  ? -13.596 -21.767 20.756  1   36.52  ? 64  VAL A CG2 1 
ATOM   525  N  N   . LYS A 1 69  ? -16.734 -21.052 20.088  1   44.49  ? 65  LYS A N   1 
ATOM   526  C  CA  . LYS A 1 69  ? -17.718 -19.951 20.165  1   45.01  ? 65  LYS A CA  1 
ATOM   527  C  C   . LYS A 1 69  ? -17.136 -18.665 20.741  1   45.55  ? 65  LYS A C   1 
ATOM   528  O  O   . LYS A 1 69  ? -16.535 -18.718 21.822  1   54.32  ? 65  LYS A O   1 
ATOM   529  C  CB  . LYS A 1 69  ? -18.898 -20.377 21.038  1   48.17  ? 65  LYS A CB  1 
ATOM   530  C  CG  . LYS A 1 69  ? -19.997 -19.336 21.118  1   61.78  ? 65  LYS A CG  1 
ATOM   531  C  CD  . LYS A 1 69  ? -20.74  -19.125 19.808  1   74.15  ? 65  LYS A CD  1 
ATOM   532  C  CE  . LYS A 1 69  ? -21.811 -18.096 19.927  1   81.82  ? 65  LYS A CE  1 
ATOM   533  N  NZ  . LYS A 1 69  ? -22.861 -18.541 20.845  1   92.36  ? 65  LYS A NZ  1 
ATOM   534  N  N   . LEU A 1 70  ? -17.301 -17.563 20.016  1   41.82  ? 66  LEU A N   1 
ATOM   535  C  CA  . LEU A 1 70  ? -16.933 -16.247 20.579  1   39.44  ? 66  LEU A CA  1 
ATOM   536  C  C   . LEU A 1 70  ? -18.126 -15.875 21.45   1   41.16  ? 66  LEU A C   1 
ATOM   537  O  O   . LEU A 1 70  ? -19.213 -15.661 20.901  1   43.61  ? 66  LEU A O   1 
ATOM   538  C  CB  . LEU A 1 70  ? -16.626 -15.178 19.535  1   39.89  ? 66  LEU A CB  1 
ATOM   539  C  CG  . LEU A 1 70  ? -15.978 -13.892 20.053  1   41.76  ? 66  LEU A CG  1 
ATOM   540  C  CD1 . LEU A 1 70  ? -14.745 -14.204 20.875  1   39.82  ? 66  LEU A CD1 1 
ATOM   541  C  CD2 . LEU A 1 70  ? -15.623 -13.015 18.87   1   40.44  ? 66  LEU A CD2 1 
ATOM   542  N  N   . LEU A 1 71  ? -17.923 -15.849 22.753  1   40.37  ? 67  LEU A N   1 
ATOM   543  C  CA  . LEU A 1 71  ? -18.971 -15.593 23.732  1   42.3   ? 67  LEU A CA  1 
ATOM   544  C  C   . LEU A 1 71  ? -19.19  -14.098 23.906  1   43.26  ? 67  LEU A C   1 
ATOM   545  O  O   . LEU A 1 71  ? -20.315 -13.683 24.171  1   42.9   ? 67  LEU A O   1 
ATOM   546  C  CB  . LEU A 1 71  ? -18.636 -16.237 25.079  1   44.25  ? 67  LEU A CB  1 
ATOM   547  C  CG  . LEU A 1 71  ? -18.431 -17.761 25.019  1   49.93  ? 67  LEU A CG  1 
ATOM   548  C  CD1 . LEU A 1 71  ? -18.042 -18.342 26.372  1   44.07  ? 67  LEU A CD1 1 
ATOM   549  C  CD2 . LEU A 1 71  ? -19.672 -18.482 24.442  1   43.6   ? 67  LEU A CD2 1 
ATOM   550  N  N   . ASP A 1 72  ? -18.107 -13.315 23.811  1   42.9   ? 68  ASP A N   1 
ATOM   551  C  CA  . ASP A 1 72  ? -18.174 -11.902 24.132  1   43.08  ? 68  ASP A CA  1 
ATOM   552  C  C   . ASP A 1 72  ? -16.899 -11.207 23.687  1   41.34  ? 68  ASP A C   1 
ATOM   553  O  O   . ASP A 1 72  ? -15.902 -11.879 23.419  1   43.03  ? 68  ASP A O   1 
ATOM   554  C  CB  . ASP A 1 72  ? -18.39  -11.681 25.623  1   45.5   ? 68  ASP A CB  1 
ATOM   555  C  CG  . ASP A 1 72  ? -19.117 -10.382 25.914  1   50.22  ? 68  ASP A CG  1 
ATOM   556  O  OD1 . ASP A 1 72  ? -19.42  -9.638  24.954  1   53.27  ? 68  ASP A OD1 1 
ATOM   557  O  OD2 . ASP A 1 72  ? -19.41  -10.142 27.077  1   58.69  ? 68  ASP A OD2 1 
ATOM   558  N  N   . VAL A 1 73  ? -16.963 -9.871  23.645  1   38.87  ? 69  VAL A N   1 
ATOM   559  C  CA  . VAL A 1 73  ? -15.829 -9.013  23.368  1   41.83  ? 69  VAL A CA  1 
ATOM   560  C  C   . VAL A 1 73  ? -15.89  -7.835  24.343  1   47.01  ? 69  VAL A C   1 
ATOM   561  O  O   . VAL A 1 73  ? -16.853 -7.069  24.323  1   48.37  ? 69  VAL A O   1 
ATOM   562  C  CB  . VAL A 1 73  ? -15.871 -8.514  21.906  1   42.96  ? 69  VAL A CB  1 
ATOM   563  C  CG1 . VAL A 1 73  ? -14.807 -7.443  21.612  1   41.65  ? 69  VAL A CG1 1 
ATOM   564  C  CG2 . VAL A 1 73  ? -15.824 -9.657  20.895  1   38.45  ? 69  VAL A CG2 1 
ATOM   565  N  N   . ILE A 1 74  ? -14.868 -7.712  25.207  1   49.93  ? 70  ILE A N   1 
ATOM   566  C  CA  . ILE A 1 74  ? -14.794 -6.629  26.176  1   56.26  ? 70  ILE A CA  1 
ATOM   567  C  C   . ILE A 1 74  ? -13.809 -5.572  25.675  1   61.31  ? 70  ILE A C   1 
ATOM   568  O  O   . ILE A 1 74  ? -12.631 -5.842  25.424  1   58.22  ? 70  ILE A O   1 
ATOM   569  C  CB  . ILE A 1 74  ? -14.494 -7.17   27.585  1   61.12  ? 70  ILE A CB  1 
ATOM   570  C  CG1 . ILE A 1 74  ? -15.628 -8.071  28.054  1   60.58  ? 70  ILE A CG1 1 
ATOM   571  C  CG2 . ILE A 1 74  ? -14.26  -6.035  28.584  1   57.86  ? 70  ILE A CG2 1 
ATOM   572  C  CD1 . ILE A 1 74  ? -15.136 -9.33   28.725  1   63.16  ? 70  ILE A CD1 1 
ATOM   573  N  N   . HIS A 1 75  ? -14.355 -4.368  25.464  1   75.39  ? 71  HIS A N   1 
ATOM   574  C  CA  . HIS A 1 75  ? -13.756 -3.376  24.578  1   91.79  ? 71  HIS A CA  1 
ATOM   575  C  C   . HIS A 1 75  ? -13.378 -2.134  25.381  1   94.03  ? 71  HIS A C   1 
ATOM   576  O  O   . HIS A 1 75  ? -14.146 -1.18   25.404  1   112.63 ? 71  HIS A O   1 
ATOM   577  C  CB  . HIS A 1 75  ? -14.697 -3.116  23.38   1   93.9   ? 71  HIS A CB  1 
ATOM   578  C  CG  . HIS A 1 75  ? -14.15  -2.307  22.252  1   116.75 ? 71  HIS A CG  1 
ATOM   579  N  ND1 . HIS A 1 75  ? -14.964 -1.603  21.387  1   131.67 ? 71  HIS A ND1 1 
ATOM   580  C  CD2 . HIS A 1 75  ? -12.897 -2.083  21.84   1   127.93 ? 71  HIS A CD2 1 
ATOM   581  C  CE1 . HIS A 1 75  ? -14.213 -0.963  20.504  1   132.4  ? 71  HIS A CE1 1 
ATOM   582  N  NE2 . HIS A 1 75  ? -12.955 -1.255  20.753  1   128.83 ? 71  HIS A NE2 1 
ATOM   583  N  N   . THR A 1 76  ? -12.199 -2.139  26.023  1   101.14 ? 72  THR A N   1 
ATOM   584  C  CA  . THR A 1 76  ? -11.717 -0.961  26.743  1   112.81 ? 72  THR A CA  1 
ATOM   585  C  C   . THR A 1 76  ? -10.973 -0.036  25.764  1   123.09 ? 72  THR A C   1 
ATOM   586  O  O   . THR A 1 76  ? -10.928 -0.301  24.552  1   99.61  ? 72  THR A O   1 
ATOM   587  C  CB  . THR A 1 76  ? -10.89  -1.375  27.97   1   106.91 ? 72  THR A CB  1 
ATOM   588  O  OG1 . THR A 1 76  ? -11.66  -2.139  28.898  1   114.1  ? 72  THR A OG1 1 
ATOM   589  C  CG2 . THR A 1 76  ? -10.254 -0.187  28.667  1   94.92  ? 72  THR A CG2 1 
ATOM   590  N  N   . GLU A 1 77  ? -10.414 1.075   26.278  1   130.69 ? 73  GLU A N   1 
ATOM   591  C  CA  . GLU A 1 77  ? -9.715  2.022   25.418  1   132.2  ? 73  GLU A CA  1 
ATOM   592  C  C   . GLU A 1 77  ? -8.288  1.545   25.156  1   125.05 ? 73  GLU A C   1 
ATOM   593  O  O   . GLU A 1 77  ? -7.737  1.804   24.088  1   118.15 ? 73  GLU A O   1 
ATOM   594  C  CB  . GLU A 1 77  ? -9.804  3.436   25.977  1   141.34 ? 73  GLU A CB  1 
ATOM   595  C  CG  . GLU A 1 77  ? -11.252 3.846   26.226  1   147.96 ? 73  GLU A CG  1 
ATOM   596  C  CD  . GLU A 1 77  ? -11.412 4.917   27.284  1   158.44 ? 73  GLU A CD  1 
ATOM   597  O  OE1 . GLU A 1 77  ? -10.424 5.62    27.598  1   157.44 ? 73  GLU A OE1 1 
ATOM   598  O  OE2 . GLU A 1 77  ? -12.541 5.063   27.811  1   156.17 ? 73  GLU A OE2 1 
ATOM   599  N  N   . ASN A 1 78  ? -7.735  0.804   26.127  1   124.91 ? 74  ASN A N   1 
ATOM   600  C  CA  . ASN A 1 78  ? -6.376  0.275   26.079  1   119.24 ? 74  ASN A CA  1 
ATOM   601  C  C   . ASN A 1 78  ? -6.326  -1.195  25.64   1   99.69  ? 74  ASN A C   1 
ATOM   602  O  O   . ASN A 1 78  ? -5.308  -1.633  25.099  1   100.19 ? 74  ASN A O   1 
ATOM   603  C  CB  . ASN A 1 78  ? -5.69   0.398   27.434  1   128.68 ? 74  ASN A CB  1 
ATOM   604  C  CG  . ASN A 1 78  ? -6.592  -0.117  28.533  1   135.37 ? 74  ASN A CG  1 
ATOM   605  O  OD1 . ASN A 1 78  ? -6.501  -1.287  28.931  1   142.73 ? 74  ASN A OD1 1 
ATOM   606  N  ND2 . ASN A 1 78  ? -7.503  0.726   28.998  1   126.19 ? 74  ASN A ND2 1 
ATOM   607  N  N   . LYS A 1 79  ? -7.384  -1.979  25.915  1   93.36  ? 75  LYS A N   1 
ATOM   608  C  CA  . LYS A 1 79  ? -7.323  -3.427  25.713  1   83.93  ? 75  LYS A CA  1 
ATOM   609  C  C   . LYS A 1 79  ? -8.595  -4.006  25.089  1   73     ? 75  LYS A C   1 
ATOM   610  O  O   . LYS A 1 79  ? -9.7    -3.475  25.257  1   70.41  ? 75  LYS A O   1 
ATOM   611  C  CB  . LYS A 1 79  ? -7.02   -4.151  27.031  1   86.01  ? 75  LYS A CB  1 
ATOM   612  C  CG  . LYS A 1 79  ? -5.618  -4.722  27.148  1   93.71  ? 75  LYS A CG  1 
ATOM   613  C  CD  . LYS A 1 79  ? -5.273  -5.105  28.583  1   102.64 ? 75  LYS A CD  1 
ATOM   614  C  CE  . LYS A 1 79  ? -4.534  -4.097  29.408  1   112.86 ? 75  LYS A CE  1 
ATOM   615  N  NZ  . LYS A 1 79  ? -3.116  -4.112  29.022  1   120.77 ? 75  LYS A NZ  1 
ATOM   616  N  N   . LEU A 1 80  ? -8.413  -5.132  24.397  1   62.36  ? 76  LEU A N   1 
ATOM   617  C  CA  . LEU A 1 80  ? -9.521  -5.865  23.823  1   59.95  ? 76  LEU A CA  1 
ATOM   618  C  C   . LEU A 1 80  ? -9.486  -7.295  24.357  1   58.63  ? 76  LEU A C   1 
ATOM   619  O  O   . LEU A 1 80  ? -8.457  -7.961  24.281  1   59.8   ? 76  LEU A O   1 
ATOM   620  C  CB  . LEU A 1 80  ? -9.363  -5.816  22.3    1   57.08  ? 76  LEU A CB  1 
ATOM   621  C  CG  . LEU A 1 80  ? -10.641 -6.004  21.476  1   51.68  ? 76  LEU A CG  1 
ATOM   622  C  CD1 . LEU A 1 80  ? -11.686 -4.987  21.966  1   53.74  ? 76  LEU A CD1 1 
ATOM   623  C  CD2 . LEU A 1 80  ? -10.309 -5.843  20.013  1   50.4   ? 76  LEU A CD2 1 
ATOM   624  N  N   . TYR A 1 81  ? -10.62  -7.769  24.882  1   58.22  ? 77  TYR A N   1 
ATOM   625  C  CA  . TYR A 1 81  ? -10.707 -9.118  25.441  1   54.84  ? 77  TYR A CA  1 
ATOM   626  C  C   . TYR A 1 81  ? -11.709 -9.945  24.646  1   51.16  ? 77  TYR A C   1 
ATOM   627  O  O   . TYR A 1 81  ? -12.897 -9.635  24.628  1   50.07  ? 77  TYR A O   1 
ATOM   628  C  CB  . TYR A 1 81  ? -11.131 -9.057  26.913  1   56.59  ? 77  TYR A CB  1 
ATOM   629  C  CG  . TYR A 1 81  ? -9.989  -8.699  27.855  1   62.75  ? 77  TYR A CG  1 
ATOM   630  C  CD1 . TYR A 1 81  ? -9.04   -9.648  28.214  1   65.12  ? 77  TYR A CD1 1 
ATOM   631  C  CD2 . TYR A 1 81  ? -9.846  -7.41   28.366  1   65.47  ? 77  TYR A CD2 1 
ATOM   632  C  CE1 . TYR A 1 81  ? -7.989  -9.333  29.063  1   67.47  ? 77  TYR A CE1 1 
ATOM   633  C  CE2 . TYR A 1 81  ? -8.801  -7.079  29.215  1   69.91  ? 77  TYR A CE2 1 
ATOM   634  C  CZ  . TYR A 1 81  ? -7.865  -8.044  29.558  1   72.16  ? 77  TYR A CZ  1 
ATOM   635  O  OH  . TYR A 1 81  ? -6.841  -7.717  30.408  1   82.06  ? 77  TYR A OH  1 
ATOM   636  N  N   . LEU A 1 82  ? -11.224 -10.986 23.968  1   48.6   ? 78  LEU A N   1 
ATOM   637  C  CA  . LEU A 1 82  ? -12.118 -11.956 23.354  1   48.32  ? 78  LEU A CA  1 
ATOM   638  C  C   . LEU A 1 82  ? -12.419 -13.073 24.357  1   52.69  ? 78  LEU A C   1 
ATOM   639  O  O   . LEU A 1 82  ? -11.49  -13.745 24.802  1   57.82  ? 78  LEU A O   1 
ATOM   640  C  CB  . LEU A 1 82  ? -11.499 -12.545 22.092  1   45.99  ? 78  LEU A CB  1 
ATOM   641  C  CG  . LEU A 1 82  ? -11.687 -11.757 20.796  1   47.91  ? 78  LEU A CG  1 
ATOM   642  C  CD1 . LEU A 1 82  ? -10.927 -10.442 20.935  1   44.41  ? 78  LEU A CD1 1 
ATOM   643  C  CD2 . LEU A 1 82  ? -11.339 -12.511 19.532  1   46.67  ? 78  LEU A CD2 1 
ATOM   644  N  N   . VAL A 1 83  ? -13.701 -13.261 24.721  1   49.34  ? 79  VAL A N   1 
ATOM   645  C  CA  . VAL A 1 83  ? -14.107 -14.364 25.585  1   46.08  ? 79  VAL A CA  1 
ATOM   646  C  C   . VAL A 1 83  ? -14.554 -15.541 24.727  1   46.12  ? 79  VAL A C   1 
ATOM   647  O  O   . VAL A 1 83  ? -15.517 -15.426 23.972  1   49.82  ? 79  VAL A O   1 
ATOM   648  C  CB  . VAL A 1 83  ? -15.254 -13.987 26.527  1   45.27  ? 79  VAL A CB  1 
ATOM   649  C  CG1 . VAL A 1 83  ? -15.502 -15.07  27.571  1   41.98  ? 79  VAL A CG1 1 
ATOM   650  C  CG2 . VAL A 1 83  ? -15.019 -12.632 27.168  1   46.73  ? 79  VAL A CG2 1 
ATOM   651  N  N   . PHE A 1 84  ? -13.869 -16.678 24.884  1   45.15  ? 80  PHE A N   1 
ATOM   652  C  CA  . PHE A 1 84  ? -14.161 -17.885 24.122  1   48.39  ? 80  PHE A CA  1 
ATOM   653  C  C   . PHE A 1 84  ? -14.619 -19.005 25.057  1   48.91  ? 80  PHE A C   1 
ATOM   654  O  O   . PHE A 1 84  ? -14.203 -19.09  26.198  1   53.38  ? 80  PHE A O   1 
ATOM   655  C  CB  . PHE A 1 84  ? -12.938 -18.427 23.379  1   42.39  ? 80  PHE A CB  1 
ATOM   656  C  CG  . PHE A 1 84  ? -12.405 -17.617 22.213  1   41.61  ? 80  PHE A CG  1 
ATOM   657  C  CD1 . PHE A 1 84  ? -11.45  -16.623 22.391  1   40.86  ? 80  PHE A CD1 1 
ATOM   658  C  CD2 . PHE A 1 84  ? -12.837 -17.899 20.922  1   40.16  ? 80  PHE A CD2 1 
ATOM   659  C  CE1 . PHE A 1 84  ? -10.961 -15.923 21.295  1   46.81  ? 80  PHE A CE1 1 
ATOM   660  C  CE2 . PHE A 1 84  ? -12.331 -17.202 19.839  1   41.26  ? 80  PHE A CE2 1 
ATOM   661  C  CZ  . PHE A 1 84  ? -11.4   -16.212 20.02   1   41.83  ? 80  PHE A CZ  1 
ATOM   662  N  N   . GLU A 1 85  ? -15.477 -19.876 24.542  1   47.49  ? 81  GLU A N   1 
ATOM   663  C  CA  . GLU A 1 85  ? -15.674 -21.2   25.095  1   45.47  ? 81  GLU A CA  1 
ATOM   664  C  C   . GLU A 1 85  ? -14.318 -21.849 25.363  1   47.32  ? 81  GLU A C   1 
ATOM   665  O  O   . GLU A 1 85  ? -13.412 -21.793 24.523  1   48.6   ? 81  GLU A O   1 
ATOM   666  C  CB  . GLU A 1 85  ? -16.35  -21.934 23.938  1   48.89  ? 81  GLU A CB  1 
ATOM   667  C  CG  . GLU A 1 85  ? -16.626 -23.407 24.193  1   56.5   ? 81  GLU A CG  1 
ATOM   668  C  CD  . GLU A 1 85  ? -17.139 -24.077 22.938  1   53     ? 81  GLU A CD  1 
ATOM   669  O  OE1 . GLU A 1 85  ? -17.677 -25.184 23.11   1   60.11  ? 81  GLU A OE1 1 
ATOM   670  O  OE2 . GLU A 1 85  ? -16.962 -23.545 21.825  1   50.46  ? 81  GLU A OE2 1 
ATOM   671  N  N   . PHE A 1 86  ? -14.196 -22.506 26.521  1   47.27  ? 82  PHE A N   1 
ATOM   672  C  CA  . PHE A 1 86  ? -12.959 -23.175 26.892  1   47.49  ? 82  PHE A CA  1 
ATOM   673  C  C   . PHE A 1 86  ? -13.031 -24.662 26.546  1   47.03  ? 82  PHE A C   1 
ATOM   674  O  O   . PHE A 1 86  ? -14.02  -25.314 26.869  1   48.26  ? 82  PHE A O   1 
ATOM   675  C  CB  . PHE A 1 86  ? -12.721 -23.065 28.399  1   52.18  ? 82  PHE A CB  1 
ATOM   676  C  CG  . PHE A 1 86  ? -11.529 -23.871 28.889  1   56.3   ? 82  PHE A CG  1 
ATOM   677  C  CD1 . PHE A 1 86  ? -10.226 -23.388 28.749  1   53.63  ? 82  PHE A CD1 1 
ATOM   678  C  CD2 . PHE A 1 86  ? -11.721 -25.142 29.443  1   53.62  ? 82  PHE A CD2 1 
ATOM   679  C  CE1 . PHE A 1 86  ? -9.153  -24.171 29.171  1   53.54  ? 82  PHE A CE1 1 
ATOM   680  C  CE2 . PHE A 1 86  ? -10.646 -25.908 29.87   1   50     ? 82  PHE A CE2 1 
ATOM   681  C  CZ  . PHE A 1 86  ? -9.366  -25.42  29.738  1   52     ? 82  PHE A CZ  1 
ATOM   682  N  N   . LEU A 1 87  ? -11.955 -25.183 25.935  1   45.47  ? 83  LEU A N   1 
ATOM   683  C  CA  . LEU A 1 87  ? -11.766 -26.602 25.667  1   49.99  ? 83  LEU A CA  1 
ATOM   684  C  C   . LEU A 1 87  ? -10.378 -26.994 26.166  1   54.2   ? 83  LEU A C   1 
ATOM   685  O  O   . LEU A 1 87  ? -9.426  -26.251 25.931  1   52.89  ? 83  LEU A O   1 
ATOM   686  C  CB  . LEU A 1 87  ? -11.879 -26.879 24.17   1   46.37  ? 83  LEU A CB  1 
ATOM   687  C  CG  . LEU A 1 87  ? -13.251 -26.695 23.516  1   49.37  ? 83  LEU A CG  1 
ATOM   688  C  CD1 . LEU A 1 87  ? -13.439 -25.283 22.959  1   45.68  ? 83  LEU A CD1 1 
ATOM   689  C  CD2 . LEU A 1 87  ? -13.41  -27.732 22.403  1   48.9   ? 83  LEU A CD2 1 
ATOM   690  N  N   . HIS A 1 88  ? -10.269 -28.162 26.822  1   56.29  ? 84  HIS A N   1 
ATOM   691  C  CA  . HIS A 1 88  ? -9.081  -28.517 27.587  1   57.48  ? 84  HIS A CA  1 
ATOM   692  C  C   . HIS A 1 88  ? -7.822  -28.733 26.726  1   59.15  ? 84  HIS A C   1 
ATOM   693  O  O   . HIS A 1 88  ? -6.709  -28.532 27.202  1   57.25  ? 84  HIS A O   1 
ATOM   694  C  CB  . HIS A 1 88  ? -9.399  -29.639 28.582  1   65.81  ? 84  HIS A CB  1 
ATOM   695  C  CG  . HIS A 1 88  ? -9.387  -31.021 28.005  1   86.29  ? 84  HIS A CG  1 
ATOM   696  N  ND1 . HIS A 1 88  ? -8.495  -32.01  28.373  1   97.11  ? 84  HIS A ND1 1 
ATOM   697  C  CD2 . HIS A 1 88  ? -10.202 -31.594 27.101  1   108.09 ? 84  HIS A CD2 1 
ATOM   698  C  CE1 . HIS A 1 88  ? -8.756  -33.133 27.705  1   104.27 ? 84  HIS A CE1 1 
ATOM   699  N  NE2 . HIS A 1 88  ? -9.8    -32.908 26.928  1   116.07 ? 84  HIS A NE2 1 
ATOM   700  N  N   . GLN A 1 89  ? -7.944  -29.129 25.455  1   57.32  ? 85  GLN A N   1 
ATOM   701  C  CA  . GLN A 1 89  ? -6.737  -29.561 24.757  1   56.84  ? 85  GLN A CA  1 
ATOM   702  C  C   . GLN A 1 89  ? -6.826  -29.222 23.27   1   51.01  ? 85  GLN A C   1 
ATOM   703  O  O   . GLN A 1 89  ? -7.911  -28.894 22.811  1   51.89  ? 85  GLN A O   1 
ATOM   704  C  CB  . GLN A 1 89  ? -6.59   -31.067 24.997  1   59.79  ? 85  GLN A CB  1 
ATOM   705  C  CG  . GLN A 1 89  ? -5.302  -31.635 24.426  1   62.44  ? 85  GLN A CG  1 
ATOM   706  C  CD  . GLN A 1 89  ? -4.822  -32.827 25.199  1   70.56  ? 85  GLN A CD  1 
ATOM   707  O  OE1 . GLN A 1 89  ? -4.008  -32.667 26.105  1   92.19  ? 85  GLN A OE1 1 
ATOM   708  N  NE2 . GLN A 1 89  ? -5.317  -34.012 24.873  1   74.43  ? 85  GLN A NE2 1 
ATOM   709  N  N   . ASP A 1 90  ? -5.698  -29.289 22.532  1   46.85  ? 86  ASP A N   1 
ATOM   710  C  CA  . ASP A 1 90  ? -5.697  -29.292 21.065  1   49.77  ? 86  ASP A CA  1 
ATOM   711  C  C   . ASP A 1 90  ? -5.309  -30.687 20.525  1   50.45  ? 86  ASP A C   1 
ATOM   712  O  O   . ASP A 1 90  ? -4.804  -31.531 21.264  1   51.35  ? 86  ASP A O   1 
ATOM   713  C  CB  . ASP A 1 90  ? -4.82   -28.179 20.507  1   49.55  ? 86  ASP A CB  1 
ATOM   714  C  CG  . ASP A 1 90  ? -3.35   -28.349 20.831  1   53.16  ? 86  ASP A CG  1 
ATOM   715  O  OD1 . ASP A 1 90  ? -2.796  -29.369 20.441  1   55.36  ? 86  ASP A OD1 1 
ATOM   716  O  OD2 . ASP A 1 90  ? -2.785  -27.481 21.497  1   70.61  ? 86  ASP A OD2 1 
ATOM   717  N  N   . LEU A 1 91  ? -5.508  -30.935 19.219  1   46.52  ? 87  LEU A N   1 
ATOM   718  C  CA  . LEU A 1 91  ? -5.318  -32.262 18.645  1   48.77  ? 87  LEU A CA  1 
ATOM   719  C  C   . LEU A 1 91  ? -3.841  -32.657 18.629  1   53.97  ? 87  LEU A C   1 
ATOM   720  O  O   . LEU A 1 91  ? -3.518  -33.856 18.674  1   53.6   ? 87  LEU A O   1 
ATOM   721  C  CB  . LEU A 1 91  ? -5.892  -32.282 17.233  1   45.96  ? 87  LEU A CB  1 
ATOM   722  C  CG  . LEU A 1 91  ? -5.668  -33.582 16.453  1   44.82  ? 87  LEU A CG  1 
ATOM   723  C  CD1 . LEU A 1 91  ? -6.467  -34.7   17.09   1   41.29  ? 87  LEU A CD1 1 
ATOM   724  C  CD2 . LEU A 1 91  ? -6.053  -33.422 14.987  1   40.71  ? 87  LEU A CD2 1 
ATOM   725  N  N   . LYS A 1 92  ? -2.97   -31.637 18.512  1   48.41  ? 88  LYS A N   1 
ATOM   726  C  CA  . LYS A 1 92  ? -1.527  -31.81  18.456  1   52.94  ? 88  LYS A CA  1 
ATOM   727  C  C   . LYS A 1 92  ? -1.011  -32.397 19.774  1   62.92  ? 88  LYS A C   1 
ATOM   728  O  O   . LYS A 1 92  ? -0.297  -33.409 19.769  1   61.42  ? 88  LYS A O   1 
ATOM   729  C  CB  . LYS A 1 92  ? -0.87   -30.486 18.062  1   54.28  ? 88  LYS A CB  1 
ATOM   730  C  CG  . LYS A 1 92  ? 0.601   -30.284 18.372  1   51.37  ? 88  LYS A CG  1 
ATOM   731  C  CD  . LYS A 1 92  ? 1.501   -31.48  18.151  1   62.59  ? 88  LYS A CD  1 
ATOM   732  C  CE  . LYS A 1 92  ? 1.475   -32.062 16.782  1   73.64  ? 88  LYS A CE  1 
ATOM   733  N  NZ  . LYS A 1 92  ? 2.693   -32.859 16.589  1   70.31  ? 88  LYS A NZ  1 
ATOM   734  N  N   . LYS A 1 93  ? -1.378  -31.758 20.899  1   59.62  ? 89  LYS A N   1 
ATOM   735  C  CA  . LYS A 1 93  ? -1.032  -32.233 22.232  1   58.49  ? 89  LYS A CA  1 
ATOM   736  C  C   . LYS A 1 93  ? -1.625  -33.624 22.449  1   56.29  ? 89  LYS A C   1 
ATOM   737  O  O   . LYS A 1 93  ? -0.961  -34.482 23.003  1   60.86  ? 89  LYS A O   1 
ATOM   738  C  CB  . LYS A 1 93  ? -1.402  -31.23  23.332  1   58     ? 89  LYS A CB  1 
ATOM   739  C  CG  . LYS A 1 93  ? -0.584  -29.96  23.219  1   76.27  ? 89  LYS A CG  1 
ATOM   740  C  CD  . LYS A 1 93  ? -0.827  -28.923 24.306  1   87.47  ? 89  LYS A CD  1 
ATOM   741  C  CE  . LYS A 1 93  ? -0.001  -27.698 24.071  1   87.87  ? 89  LYS A CE  1 
ATOM   742  N  NZ  . LYS A 1 93  ? -0.505  -26.603 24.9    1   98.47  ? 89  LYS A NZ  1 
ATOM   743  N  N   . PHE A 1 94  ? -2.853  -33.855 21.972  1   52.03  ? 90  PHE A N   1 
ATOM   744  C  CA  . PHE A 1 94  ? -3.502  -35.139 22.15   1   52.58  ? 90  PHE A CA  1 
ATOM   745  C  C   . PHE A 1 94  ? -2.707  -36.225 21.426  1   56.18  ? 90  PHE A C   1 
ATOM   746  O  O   . PHE A 1 94  ? -2.44   -37.275 21.998  1   55.36  ? 90  PHE A O   1 
ATOM   747  C  CB  . PHE A 1 94  ? -4.965  -35.063 21.708  1   52.63  ? 90  PHE A CB  1 
ATOM   748  C  CG  . PHE A 1 94  ? -5.683  -36.401 21.816  1   54.56  ? 90  PHE A CG  1 
ATOM   749  C  CD1 . PHE A 1 94  ? -5.893  -36.994 23.052  1   56.62  ? 90  PHE A CD1 1 
ATOM   750  C  CD2 . PHE A 1 94  ? -6.134  -37.07  20.68   1   54.51  ? 90  PHE A CD2 1 
ATOM   751  C  CE1 . PHE A 1 94  ? -6.52   -38.23  23.149  1   56.62  ? 90  PHE A CE1 1 
ATOM   752  C  CE2 . PHE A 1 94  ? -6.787  -38.288 20.786  1   56.5   ? 90  PHE A CE2 1 
ATOM   753  C  CZ  . PHE A 1 94  ? -6.968  -38.872 22.023  1   57.93  ? 90  PHE A CZ  1 
ATOM   754  N  N   . MET A 1 95  ? -2.305  -35.973 20.175  1   59.17  ? 91  MET A N   1 
ATOM   755  C  CA  . MET A 1 95  ? -1.559  -36.971 19.412  1   62.81  ? 91  MET A CA  1 
ATOM   756  C  C   . MET A 1 95  ? -0.178  -37.281 20      1   65.91  ? 91  MET A C   1 
ATOM   757  O  O   . MET A 1 95  ? 0.303   -38.403 19.834  1   69.41  ? 91  MET A O   1 
ATOM   758  C  CB  . MET A 1 95  ? -1.363  -36.537 17.961  1   56.8   ? 91  MET A CB  1 
ATOM   759  C  CG  . MET A 1 95  ? -2.536  -36.862 17.099  1   57.15  ? 91  MET A CG  1 
ATOM   760  S  SD  . MET A 1 95  ? -2.21   -36.163 15.475  1   68.36  ? 91  MET A SD  1 
ATOM   761  C  CE  . MET A 1 95  ? -1.94   -34.438 15.881  1   52.73  ? 91  MET A CE  1 
ATOM   762  N  N   . ASP A 1 96  ? 0.439   -36.287 20.66   1   64.99  ? 92  ASP A N   1 
ATOM   763  C  CA  . ASP A 1 96  ? 1.792   -36.385 21.183  1   66.88  ? 92  ASP A CA  1 
ATOM   764  C  C   . ASP A 1 96  ? 1.804   -37.111 22.518  1   71.89  ? 92  ASP A C   1 
ATOM   765  O  O   . ASP A 1 96  ? 2.75    -37.834 22.803  1   81.9   ? 92  ASP A O   1 
ATOM   766  C  CB  . ASP A 1 96  ? 2.436   -35.025 21.399  1   62.03  ? 92  ASP A CB  1 
ATOM   767  C  CG  . ASP A 1 96  ? 2.886   -34.337 20.125  1   69.5   ? 92  ASP A CG  1 
ATOM   768  O  OD1 . ASP A 1 96  ? 3.07    -35.063 19.105  1   68.92  ? 92  ASP A OD1 1 
ATOM   769  O  OD2 . ASP A 1 96  ? 3.005   -33.09  20.161  1   73.21  ? 92  ASP A OD2 1 
ATOM   770  N  N   . ALA A 1 97  ? 0.776   -36.879 23.334  1   77.73  ? 93  ALA A N   1 
ATOM   771  C  CA  . ALA A 1 97  ? 0.89    -37.197 24.746  1   89.36  ? 93  ALA A CA  1 
ATOM   772  C  C   . ALA A 1 97  ? 0.095   -38.452 25.108  1   90.71  ? 93  ALA A C   1 
ATOM   773  O  O   . ALA A 1 97  ? 0.478   -39.198 26.017  1   98.77  ? 93  ALA A O   1 
ATOM   774  C  CB  . ALA A 1 97  ? 0.518   -35.983 25.575  1   83.46  ? 93  ALA A CB  1 
ATOM   775  N  N   . SER A 1 98  ? -1.004  -38.688 24.394  1   87.65  ? 94  SER A N   1 
ATOM   776  C  CA  . SER A 1 98  ? -1.882  -39.779 24.778  1   104.4  ? 94  SER A CA  1 
ATOM   777  C  C   . SER A 1 98  ? -2.072  -40.737 23.61   1   97.49  ? 94  SER A C   1 
ATOM   778  O  O   . SER A 1 98  ? -2.571  -41.848 23.792  1   119.33 ? 94  SER A O   1 
ATOM   779  C  CB  . SER A 1 98  ? -3.2    -39.282 25.377  1   108.06 ? 94  SER A CB  1 
ATOM   780  O  OG  . SER A 1 98  ? -4.236  -40.253 25.294  1   101.29 ? 94  SER A OG  1 
ATOM   781  N  N   . ALA A 1 99  ? -1.659  -40.315 22.419  1   73.44  ? 95  ALA A N   1 
ATOM   782  C  CA  . ALA A 1 99  ? -1.899  -41.212 21.313  1   71.27  ? 95  ALA A CA  1 
ATOM   783  C  C   . ALA A 1 99  ? -0.606  -41.942 20.948  1   81.04  ? 95  ALA A C   1 
ATOM   784  O  O   . ALA A 1 99  ? -0.415  -42.321 19.805  1   80.22  ? 95  ALA A O   1 
ATOM   785  C  CB  . ALA A 1 99  ? -2.554  -40.466 20.192  1   64.99  ? 95  ALA A CB  1 
ATOM   786  N  N   . LEU A 1 100 ? 0.197   -42.27  21.969  1   100.39 ? 96  LEU A N   1 
ATOM   787  C  CA  . LEU A 1 100 ? 1.526   -42.862 21.868  1   104.42 ? 96  LEU A CA  1 
ATOM   788  C  C   . LEU A 1 100 ? 1.515   -44.171 21.083  1   108.33 ? 96  LEU A C   1 
ATOM   789  O  O   . LEU A 1 100 ? 2.481   -44.483 20.389  1   110.45 ? 96  LEU A O   1 
ATOM   790  C  CB  . LEU A 1 100 ? 2.049   -43.124 23.278  1   113.2  ? 96  LEU A CB  1 
ATOM   791  C  CG  . LEU A 1 100 ? 2.304   -41.901 24.163  1   112.12 ? 96  LEU A CG  1 
ATOM   792  C  CD1 . LEU A 1 100 ? 2.679   -42.321 25.58   1   122.06 ? 96  LEU A CD1 1 
ATOM   793  C  CD2 . LEU A 1 100 ? 3.363   -41.017 23.543  1   116.11 ? 96  LEU A CD2 1 
ATOM   794  N  N   . THR A 1 101 ? 0.465   -44.978 21.277  1   107.44 ? 97  THR A N   1 
ATOM   795  C  CA  . THR A 1 101 ? 0.301   -46.19  20.489  1   102.16 ? 97  THR A CA  1 
ATOM   796  C  C   . THR A 1 101 ? -0.871  -46.032 19.516  1   101.93 ? 97  THR A C   1 
ATOM   797  O  O   . THR A 1 101 ? -1.37   -47.019 18.974  1   107.41 ? 97  THR A O   1 
ATOM   798  C  CB  . THR A 1 101 ? 0.17    -47.428 21.381  1   106.28 ? 97  THR A CB  1 
ATOM   799  O  OG1 . THR A 1 101 ? -0.737  -47.077 22.422  1   125.27 ? 97  THR A OG1 1 
ATOM   800  C  CG2 . THR A 1 101 ? 1.499   -47.904 21.944  1   102.27 ? 97  THR A CG2 1 
ATOM   801  N  N   . GLY A 1 102 ? -1.358  -44.801 19.322  1   93.7   ? 98  GLY A N   1 
ATOM   802  C  CA  . GLY A 1 102 ? -2.307  -44.56  18.245  1   79.37  ? 98  GLY A CA  1 
ATOM   803  C  C   . GLY A 1 102 ? -3.607  -43.9   18.697  1   79.17  ? 98  GLY A C   1 
ATOM   804  O  O   . GLY A 1 102 ? -3.946  -43.93  19.879  1   82.89  ? 98  GLY A O   1 
ATOM   805  N  N   . ILE A 1 103 ? -4.308  -43.274 17.741  1   68.6   ? 99  ILE A N   1 
ATOM   806  C  CA  . ILE A 1 103 ? -5.69   -42.875 17.938  1   61.14  ? 99  ILE A CA  1 
ATOM   807  C  C   . ILE A 1 103 ? -6.546  -44.012 17.397  1   55.82  ? 99  ILE A C   1 
ATOM   808  O  O   . ILE A 1 103 ? -6.338  -44.429 16.274  1   60.46  ? 99  ILE A O   1 
ATOM   809  C  CB  . ILE A 1 103 ? -5.978  -41.554 17.203  1   63.16  ? 99  ILE A CB  1 
ATOM   810  C  CG1 . ILE A 1 103 ? -4.959  -40.472 17.539  1   63.44  ? 99  ILE A CG1 1 
ATOM   811  C  CG2 . ILE A 1 103 ? -7.404  -41.075 17.467  1   64.16  ? 99  ILE A CG2 1 
ATOM   812  C  CD1 . ILE A 1 103 ? -5.309  -39.104 16.973  1   64.04  ? 99  ILE A CD1 1 
ATOM   813  N  N   . PRO A 1 104 ? -7.495  -44.583 18.171  1   56.67  ? 100 PRO A N   1 
ATOM   814  C  CA  . PRO A 1 104 ? -8.354  -45.663 17.671  1   54.29  ? 100 PRO A CA  1 
ATOM   815  C  C   . PRO A 1 104 ? -9.17   -45.16  16.487  1   56.89  ? 100 PRO A C   1 
ATOM   816  O  O   . PRO A 1 104 ? -9.487  -43.971 16.39   1   55.72  ? 100 PRO A O   1 
ATOM   817  C  CB  . PRO A 1 104 ? -9.258  -46.074 18.835  1   58.86  ? 100 PRO A CB  1 
ATOM   818  C  CG  . PRO A 1 104 ? -8.904  -45.157 19.973  1   59.34  ? 100 PRO A CG  1 
ATOM   819  C  CD  . PRO A 1 104 ? -7.81   -44.186 19.549  1   55.63  ? 100 PRO A CD  1 
ATOM   820  N  N   . LEU A 1 105 ? -9.504  -46.083 15.585  1   60.9   ? 101 LEU A N   1 
ATOM   821  C  CA  . LEU A 1 105 ? -10.116 -45.737 14.308  1   58.06  ? 101 LEU A CA  1 
ATOM   822  C  C   . LEU A 1 105 ? -11.47  -45.054 14.525  1   57.97  ? 101 LEU A C   1 
ATOM   823  O  O   . LEU A 1 105 ? -11.737 -44.037 13.888  1   60.71  ? 101 LEU A O   1 
ATOM   824  C  CB  . LEU A 1 105 ? -10.196 -47.022 13.489  1   58.14  ? 101 LEU A CB  1 
ATOM   825  C  CG  . LEU A 1 105 ? -10.869 -46.954 12.116  1   59.15  ? 101 LEU A CG  1 
ATOM   826  C  CD1 . LEU A 1 105 ? -10.033 -46.02  11.285  1   66.74  ? 101 LEU A CD1 1 
ATOM   827  C  CD2 . LEU A 1 105 ? -11.038 -48.297 11.415  1   58.84  ? 101 LEU A CD2 1 
ATOM   828  N  N   . PRO A 1 106 ? -12.333 -45.525 15.466  1   57.05  ? 102 PRO A N   1 
ATOM   829  C  CA  . PRO A 1 106 ? -13.581 -44.836 15.789  1   52.73  ? 102 PRO A CA  1 
ATOM   830  C  C   . PRO A 1 106 ? -13.403 -43.362 16.121  1   53.13  ? 102 PRO A C   1 
ATOM   831  O  O   . PRO A 1 106 ? -14.264 -42.565 15.756  1   61.05  ? 102 PRO A O   1 
ATOM   832  C  CB  . PRO A 1 106 ? -14.16  -45.605 16.993  1   53.69  ? 102 PRO A CB  1 
ATOM   833  C  CG  . PRO A 1 106 ? -13.541 -46.988 16.875  1   51.5   ? 102 PRO A CG  1 
ATOM   834  C  CD  . PRO A 1 106 ? -12.167 -46.745 16.28   1   53.23  ? 102 PRO A CD  1 
ATOM   835  N  N   . LEU A 1 107 ? -12.31  -43.002 16.812  1   50.1   ? 103 LEU A N   1 
ATOM   836  C  CA  . LEU A 1 107 ? -12.104 -41.629 17.257  1   48.28  ? 103 LEU A CA  1 
ATOM   837  C  C   . LEU A 1 107 ? -11.573 -40.755 16.117  1   50.98  ? 103 LEU A C   1 
ATOM   838  O  O   . LEU A 1 107 ? -11.916 -39.562 16.015  1   48.68  ? 103 LEU A O   1 
ATOM   839  C  CB  . LEU A 1 107 ? -11.152 -41.641 18.449  1   51.97  ? 103 LEU A CB  1 
ATOM   840  C  CG  . LEU A 1 107 ? -11.068 -40.369 19.308  1   52.61  ? 103 LEU A CG  1 
ATOM   841  C  CD1 . LEU A 1 107 ? -12.448 -39.935 19.821  1   51.42  ? 103 LEU A CD1 1 
ATOM   842  C  CD2 . LEU A 1 107 ? -10.149 -40.692 20.497  1   53.08  ? 103 LEU A CD2 1 
ATOM   843  N  N   . ILE A 1 108 ? -10.75  -41.357 15.24   1   51.41  ? 104 ILE A N   1 
ATOM   844  C  CA  . ILE A 1 108 ? -10.244 -40.675 14.05   1   53.46  ? 104 ILE A CA  1 
ATOM   845  C  C   . ILE A 1 108 ? -11.419 -40.264 13.16   1   50.25  ? 104 ILE A C   1 
ATOM   846  O  O   . ILE A 1 108 ? -11.5   -39.15  12.621  1   45.63  ? 104 ILE A O   1 
ATOM   847  C  CB  . ILE A 1 108 ? -9.231  -41.565 13.297  1   53.95  ? 104 ILE A CB  1 
ATOM   848  C  CG1 . ILE A 1 108 ? -7.947  -41.746 14.097  1   51.3   ? 104 ILE A CG1 1 
ATOM   849  C  CG2 . ILE A 1 108 ? -8.912  -41.009 11.903  1   49.2   ? 104 ILE A CG2 1 
ATOM   850  C  CD1 . ILE A 1 108 ? -6.96   -42.688 13.429  1   51.89  ? 104 ILE A CD1 1 
ATOM   851  N  N   . LYS A 1 109 ? -12.334 -41.215 13.029  1   47.12  ? 105 LYS A N   1 
ATOM   852  C  CA  . LYS A 1 109 ? -13.471 -41.109 12.14   1   48.19  ? 105 LYS A CA  1 
ATOM   853  C  C   . LYS A 1 109 ? -14.432 -40.03  12.647  1   46.6   ? 105 LYS A C   1 
ATOM   854  O  O   . LYS A 1 109 ? -14.861 -39.164 11.883  1   47.46  ? 105 LYS A O   1 
ATOM   855  C  CB  . LYS A 1 109 ? -13.995 -42.55  12.114  1   48.3   ? 105 LYS A CB  1 
ATOM   856  C  CG  . LYS A 1 109 ? -14.941 -42.866 10.995  1   53.6   ? 105 LYS A CG  1 
ATOM   857  C  CD  . LYS A 1 109 ? -15.274 -44.354 10.964  1   53.04  ? 105 LYS A CD  1 
ATOM   858  C  CE  . LYS A 1 109 ? -14.169 -45.165 10.391  1   50.25  ? 105 LYS A CE  1 
ATOM   859  N  NZ  . LYS A 1 109 ? -14.652 -46.48  9.951   1   49.66  ? 105 LYS A NZ  1 
ATOM   860  N  N   . SER A 1 110 ? -14.766 -40.108 13.941  1   44.62  ? 106 SER A N   1 
ATOM   861  C  CA  . SER A 1 110 ? -15.522 -39.103 14.671  1   45.61  ? 106 SER A CA  1 
ATOM   862  C  C   . SER A 1 110 ? -14.897 -37.714 14.526  1   44.78  ? 106 SER A C   1 
ATOM   863  O  O   . SER A 1 110 ? -15.617 -36.76  14.259  1   45.9   ? 106 SER A O   1 
ATOM   864  C  CB  . SER A 1 110 ? -15.681 -39.486 16.127  1   46.37  ? 106 SER A CB  1 
ATOM   865  O  OG  . SER A 1 110 ? -16.103 -38.369 16.9    1   50.04  ? 106 SER A OG  1 
ATOM   866  N  N   . TYR A 1 111 ? -13.574 -37.597 14.714  1   45.37  ? 107 TYR A N   1 
ATOM   867  C  CA  . TYR A 1 111 ? -12.915 -36.298 14.656  1   47.41  ? 107 TYR A CA  1 
ATOM   868  C  C   . TYR A 1 111 ? -12.985 -35.719 13.239  1   49.84  ? 107 TYR A C   1 
ATOM   869  O  O   . TYR A 1 111 ? -13.374 -34.556 13.058  1   47.73  ? 107 TYR A O   1 
ATOM   870  C  CB  . TYR A 1 111 ? -11.481 -36.323 15.196  1   48.58  ? 107 TYR A CB  1 
ATOM   871  C  CG  . TYR A 1 111 ? -11.268 -36.351 16.71   1   55.13  ? 107 TYR A CG  1 
ATOM   872  C  CD1 . TYR A 1 111 ? -12.297 -36.064 17.614  1   56.24  ? 107 TYR A CD1 1 
ATOM   873  C  CD2 . TYR A 1 111 ? -10.027 -36.695 17.247  1   53.3   ? 107 TYR A CD2 1 
ATOM   874  C  CE1 . TYR A 1 111 ? -12.103 -36.114 18.989  1   54.28  ? 107 TYR A CE1 1 
ATOM   875  C  CE2 . TYR A 1 111 ? -9.818  -36.742 18.621  1   58.57  ? 107 TYR A CE2 1 
ATOM   876  C  CZ  . TYR A 1 111 ? -10.853 -36.44  19.492  1   57.28  ? 107 TYR A CZ  1 
ATOM   877  O  OH  . TYR A 1 111 ? -10.649 -36.468 20.84   1   66.83  ? 107 TYR A OH  1 
ATOM   878  N  N   . LEU A 1 112 ? -12.626 -36.539 12.236  1   43.15  ? 108 LEU A N   1 
ATOM   879  C  CA  . LEU A 1 112 ? -12.656 -36.066 10.856  1   46.22  ? 108 LEU A CA  1 
ATOM   880  C  C   . LEU A 1 112 ? -14.079 -35.645 10.444  1   54.77  ? 108 LEU A C   1 
ATOM   881  O  O   . LEU A 1 112 ? -14.265 -34.592 9.794   1   46.69  ? 108 LEU A O   1 
ATOM   882  C  CB  . LEU A 1 112 ? -12.061 -37.105 9.908   1   37.99  ? 108 LEU A CB  1 
ATOM   883  C  CG  . LEU A 1 112 ? -11.922 -36.662 8.451   1   36.89  ? 108 LEU A CG  1 
ATOM   884  C  CD1 . LEU A 1 112 ? -11.016 -35.406 8.3     1   35.24  ? 108 LEU A CD1 1 
ATOM   885  C  CD2 . LEU A 1 112 ? -11.468 -37.815 7.557   1   31.5   ? 108 LEU A CD2 1 
ATOM   886  N  N   . PHE A 1 113 ? -15.079 -36.457 10.863  1   45.97  ? 109 PHE A N   1 
ATOM   887  C  CA  . PHE A 1 113 ? -16.467 -36.165 10.554  1   42.01  ? 109 PHE A CA  1 
ATOM   888  C  C   . PHE A 1 113 ? -16.896 -34.813 11.137  1   43.54  ? 109 PHE A C   1 
ATOM   889  O  O   . PHE A 1 113 ? -17.56  -34.027 10.458  1   43.27  ? 109 PHE A O   1 
ATOM   890  C  CB  . PHE A 1 113 ? -17.357 -37.266 11.101  1   41.9   ? 109 PHE A CB  1 
ATOM   891  C  CG  . PHE A 1 113 ? -18.75  -37.292 10.492  1   41.33  ? 109 PHE A CG  1 
ATOM   892  C  CD1 . PHE A 1 113 ? -18.923 -37.423 9.12    1   37.34  ? 109 PHE A CD1 1 
ATOM   893  C  CD2 . PHE A 1 113 ? -19.875 -37.234 11.303  1   40.55  ? 109 PHE A CD2 1 
ATOM   894  C  CE1 . PHE A 1 113 ? -20.193 -37.503 8.581   1   40.75  ? 109 PHE A CE1 1 
ATOM   895  C  CE2 . PHE A 1 113 ? -21.147 -37.31  10.76   1   41.41  ? 109 PHE A CE2 1 
ATOM   896  C  CZ  . PHE A 1 113 ? -21.306 -37.459 9.408   1   41.23  ? 109 PHE A CZ  1 
ATOM   897  N  N   . GLN A 1 114 ? -16.495 -34.53  12.385  1   45.86  ? 110 GLN A N   1 
ATOM   898  C  CA  . GLN A 1 114 ? -16.81  -33.257 13.02   1   43.56  ? 110 GLN A CA  1 
ATOM   899  C  C   . GLN A 1 114 ? -16.08  -32.103 12.325  1   44.35  ? 110 GLN A C   1 
ATOM   900  O  O   . GLN A 1 114 ? -16.663 -31.038 12.126  1   44.05  ? 110 GLN A O   1 
ATOM   901  C  CB  . GLN A 1 114 ? -16.485 -33.294 14.502  1   39.37  ? 110 GLN A CB  1 
ATOM   902  C  CG  . GLN A 1 114 ? -17.316 -34.294 15.286  1   43.12  ? 110 GLN A CG  1 
ATOM   903  C  CD  . GLN A 1 114 ? -16.942 -34.247 16.746  1   48.36  ? 110 GLN A CD  1 
ATOM   904  O  OE1 . GLN A 1 114 ? -17.058 -33.186 17.375  1   49.86  ? 110 GLN A OE1 1 
ATOM   905  N  NE2 . GLN A 1 114 ? -16.479 -35.37  17.295  1   47.01  ? 110 GLN A NE2 1 
ATOM   906  N  N   . LEU A 1 115 ? -14.814 -32.313 11.939  1   40.06  ? 111 LEU A N   1 
ATOM   907  C  CA  . LEU A 1 115 ? -14.06  -31.244 11.31   1   39.79  ? 111 LEU A CA  1 
ATOM   908  C  C   . LEU A 1 115 ? -14.701 -30.849 9.975   1   42.28  ? 111 LEU A C   1 
ATOM   909  O  O   . LEU A 1 115 ? -14.794 -29.67  9.646   1   45.22  ? 111 LEU A O   1 
ATOM   910  C  CB  . LEU A 1 115 ? -12.618 -31.702 11.143  1   42.29  ? 111 LEU A CB  1 
ATOM   911  C  CG  . LEU A 1 115 ? -11.84  -31.848 12.451  1   43.15  ? 111 LEU A CG  1 
ATOM   912  C  CD1 . LEU A 1 115 ? -10.509 -32.54  12.237  1   42.92  ? 111 LEU A CD1 1 
ATOM   913  C  CD2 . LEU A 1 115 ? -11.636 -30.492 13.056  1   40.31  ? 111 LEU A CD2 1 
ATOM   914  N  N   . LEU A 1 116 ? -15.196 -31.833 9.226   1   41.76  ? 112 LEU A N   1 
ATOM   915  C  CA  . LEU A 1 116 ? -15.859 -31.597 7.948   1   40.92  ? 112 LEU A CA  1 
ATOM   916  C  C   . LEU A 1 116 ? -17.158 -30.815 8.121   1   39.42  ? 112 LEU A C   1 
ATOM   917  O  O   . LEU A 1 116 ? -17.475 -29.958 7.294   1   42.17  ? 112 LEU A O   1 
ATOM   918  C  CB  . LEU A 1 116 ? -16.056 -32.928 7.213   1   37.71  ? 112 LEU A CB  1 
ATOM   919  C  CG  . LEU A 1 116 ? -14.752 -33.514 6.668   1   38.74  ? 112 LEU A CG  1 
ATOM   920  C  CD1 . LEU A 1 116 ? -14.832 -35.005 6.46    1   36.72  ? 112 LEU A CD1 1 
ATOM   921  C  CD2 . LEU A 1 116 ? -14.369 -32.784 5.387   1   39.19  ? 112 LEU A CD2 1 
ATOM   922  N  N   . GLN A 1 117 ? -17.911 -31.138 9.176   1   39.12  ? 113 GLN A N   1 
ATOM   923  C  CA  . GLN A 1 117 ? -19.121 -30.404 9.5     1   40.47  ? 113 GLN A CA  1 
ATOM   924  C  C   . GLN A 1 117 ? -18.762 -28.939 9.734   1   40.61  ? 113 GLN A C   1 
ATOM   925  O  O   . GLN A 1 117 ? -19.352 -28.045 9.146   1   41.65  ? 113 GLN A O   1 
ATOM   926  C  CB  . GLN A 1 117 ? -19.803 -30.976 10.74   1   39.71  ? 113 GLN A CB  1 
ATOM   927  C  CG  . GLN A 1 117 ? -20.365 -32.38  10.536  1   40.76  ? 113 GLN A CG  1 
ATOM   928  C  CD  . GLN A 1 117 ? -21.212 -32.861 11.698  1   45.84  ? 113 GLN A CD  1 
ATOM   929  O  OE1 . GLN A 1 117 ? -22.171 -32.212 12.156  1   44.92  ? 113 GLN A OE1 1 
ATOM   930  N  NE2 . GLN A 1 117 ? -20.828 -34.017 12.207  1   46.66  ? 113 GLN A NE2 1 
ATOM   931  N  N   . GLY A 1 118 ? -17.747 -28.706 10.565  1   45.15  ? 114 GLY A N   1 
ATOM   932  C  CA  . GLY A 1 118 ? -17.31  -27.363 10.905  1   39.91  ? 114 GLY A CA  1 
ATOM   933  C  C   . GLY A 1 118 ? -16.878 -26.601 9.665   1   39.29  ? 114 GLY A C   1 
ATOM   934  O  O   . GLY A 1 118 ? -17.196 -25.419 9.509   1   40.16  ? 114 GLY A O   1 
ATOM   935  N  N   . LEU A 1 119 ? -16.149 -27.29  8.784   1   39.45  ? 115 LEU A N   1 
ATOM   936  C  CA  . LEU A 1 119 ? -15.562 -26.59  7.66    1   39.19  ? 115 LEU A CA  1 
ATOM   937  C  C   . LEU A 1 119 ? -16.644 -26.295 6.632   1   44.65  ? 115 LEU A C   1 
ATOM   938  O  O   . LEU A 1 119 ? -16.695 -25.174 6.088   1   44.55  ? 115 LEU A O   1 
ATOM   939  C  CB  . LEU A 1 119 ? -14.431 -27.431 7.092   1   37.38  ? 115 LEU A CB  1 
ATOM   940  C  CG  . LEU A 1 119 ? -13.721 -26.832 5.883   1   41.05  ? 115 LEU A CG  1 
ATOM   941  C  CD1 . LEU A 1 119 ? -13.115 -25.484 6.26    1   43.63  ? 115 LEU A CD1 1 
ATOM   942  C  CD2 . LEU A 1 119 ? -12.649 -27.823 5.455   1   40.45  ? 115 LEU A CD2 1 
ATOM   943  N  N   . ALA A 1 120 ? -17.511 -27.306 6.411   1   40.28  ? 116 ALA A N   1 
ATOM   944  C  CA  . ALA A 1 120 ? -18.673 -27.14  5.548   1   41.8   ? 116 ALA A CA  1 
ATOM   945  C  C   . ALA A 1 120 ? -19.461 -25.897 5.969   1   41.48  ? 116 ALA A C   1 
ATOM   946  O  O   . ALA A 1 120 ? -19.935 -25.149 5.121   1   48.23  ? 116 ALA A O   1 
ATOM   947  C  CB  . ALA A 1 120 ? -19.539 -28.386 5.559   1   38.53  ? 116 ALA A CB  1 
ATOM   948  N  N   . PHE A 1 121 ? -19.621 -25.689 7.28    1   36.52  ? 117 PHE A N   1 
ATOM   949  C  CA  . PHE A 1 121 ? -20.366 -24.553 7.795   1   38.36  ? 117 PHE A CA  1 
ATOM   950  C  C   . PHE A 1 121 ? -19.642 -23.254 7.437   1   41.37  ? 117 PHE A C   1 
ATOM   951  O  O   . PHE A 1 121 ? -20.287 -22.296 7.011   1   46.82  ? 117 PHE A O   1 
ATOM   952  C  CB  . PHE A 1 121 ? -20.639 -24.684 9.299   1   36.16  ? 117 PHE A CB  1 
ATOM   953  C  CG  . PHE A 1 121 ? -21.586 -23.623 9.836   1   41.32  ? 117 PHE A CG  1 
ATOM   954  C  CD1 . PHE A 1 121 ? -21.136 -22.34  10.169  1   45.2   ? 117 PHE A CD1 1 
ATOM   955  C  CD2 . PHE A 1 121 ? -22.948 -23.883 9.95    1   43.99  ? 117 PHE A CD2 1 
ATOM   956  C  CE1 . PHE A 1 121 ? -22.025 -21.361 10.609  1   45.15  ? 117 PHE A CE1 1 
ATOM   957  C  CE2 . PHE A 1 121 ? -23.833 -22.914 10.412  1   41.09  ? 117 PHE A CE2 1 
ATOM   958  C  CZ  . PHE A 1 121 ? -23.367 -21.661 10.766  1   41.24  ? 117 PHE A CZ  1 
ATOM   959  N  N   . CYS A 1 122 ? -18.307 -23.231 7.59    1   41.22  ? 118 CYS A N   1 
ATOM   960  C  CA  . CYS A 1 122 ? -17.508 -22.084 7.179   1   41.61  ? 118 CYS A CA  1 
ATOM   961  C  C   . CYS A 1 122 ? -17.724 -21.726 5.705   1   44.95  ? 118 CYS A C   1 
ATOM   962  O  O   . CYS A 1 122 ? -18.017 -20.572 5.382   1   41.91  ? 118 CYS A O   1 
ATOM   963  C  CB  . CYS A 1 122 ? -16.03  -22.332 7.437   1   41.84  ? 118 CYS A CB  1 
ATOM   964  S  SG  . CYS A 1 122 ? -15.659 -22.427 9.202   1   45.64  ? 118 CYS A SG  1 
ATOM   965  N  N   . HIS A 1 123 ? -17.597 -22.727 4.819   1   42     ? 119 HIS A N   1 
ATOM   966  C  CA  . HIS A 1 123 ? -17.662 -22.497 3.389   1   39.68  ? 119 HIS A CA  1 
ATOM   967  C  C   . HIS A 1 123 ? -19.054 -22.018 2.986   1   44.46  ? 119 HIS A C   1 
ATOM   968  O  O   . HIS A 1 123 ? -19.2   -21.157 2.106   1   44.62  ? 119 HIS A O   1 
ATOM   969  C  CB  . HIS A 1 123 ? -17.155 -23.733 2.648   1   38.69  ? 119 HIS A CB  1 
ATOM   970  C  CG  . HIS A 1 123 ? -15.708 -24.004 2.912   1   44.57  ? 119 HIS A CG  1 
ATOM   971  N  ND1 . HIS A 1 123 ? -15.087 -25.18  2.537   1   41.88  ? 119 HIS A ND1 1 
ATOM   972  C  CD2 . HIS A 1 123 ? -14.744 -23.225 3.505   1   43.27  ? 119 HIS A CD2 1 
ATOM   973  C  CE1 . HIS A 1 123 ? -13.805 -25.115 2.918   1   47.18  ? 119 HIS A CE1 1 
ATOM   974  N  NE2 . HIS A 1 123 ? -13.571 -23.929 3.499   1   44.45  ? 119 HIS A NE2 1 
ATOM   975  N  N   . SER A 1 124 ? -20.069 -22.58  3.645   1   39.82  ? 120 SER A N   1 
ATOM   976  C  CA  . SER A 1 124 ? -21.451 -22.188 3.421   1   44.62  ? 120 SER A CA  1 
ATOM   977  C  C   . SER A 1 124 ? -21.711 -20.753 3.864   1   44.18  ? 120 SER A C   1 
ATOM   978  O  O   . SER A 1 124 ? -22.71  -20.174 3.428   1   44.91  ? 120 SER A O   1 
ATOM   979  C  CB  . SER A 1 124 ? -22.401 -23.099 4.123   1   47.42  ? 120 SER A CB  1 
ATOM   980  O  OG  . SER A 1 124 ? -22.266 -24.419 3.632   1   56.55  ? 120 SER A OG  1 
ATOM   981  N  N   . HIS A 1 125 ? -20.84  -20.211 4.736   1   37.82  ? 121 HIS A N   1 
ATOM   982  C  CA  . HIS A 1 125 ? -20.954 -18.823 5.178   1   40.79  ? 121 HIS A CA  1 
ATOM   983  C  C   . HIS A 1 125 ? -19.842 -17.947 4.603   1   43.25  ? 121 HIS A C   1 
ATOM   984  O  O   . HIS A 1 125 ? -19.439 -16.984 5.233   1   44.42  ? 121 HIS A O   1 
ATOM   985  C  CB  . HIS A 1 125 ? -20.987 -18.779 6.701   1   39.38  ? 121 HIS A CB  1 
ATOM   986  C  CG  . HIS A 1 125 ? -22.246 -19.398 7.181   1   45.88  ? 121 HIS A CG  1 
ATOM   987  N  ND1 . HIS A 1 125 ? -22.484 -20.75  7.063   1   46.15  ? 121 HIS A ND1 1 
ATOM   988  C  CD2 . HIS A 1 125 ? -23.363 -18.858 7.685   1   48.08  ? 121 HIS A CD2 1 
ATOM   989  C  CE1 . HIS A 1 125 ? -23.705 -21.004 7.5     1   47.65  ? 121 HIS A CE1 1 
ATOM   990  N  NE2 . HIS A 1 125 ? -24.253 -19.872 7.884   1   47.18  ? 121 HIS A NE2 1 
ATOM   991  N  N   . ARG A 1 126 ? -19.349 -18.302 3.412   1   40.01  ? 122 ARG A N   1 
ATOM   992  C  CA  . ARG A 1 126 ? -18.326 -17.565 2.693   1   37.97  ? 122 ARG A CA  1 
ATOM   993  C  C   . ARG A 1 126 ? -17.102 -17.226 3.558   1   37.98  ? 122 ARG A C   1 
ATOM   994  O  O   . ARG A 1 126 ? -16.547 -16.147 3.392   1   40.96  ? 122 ARG A O   1 
ATOM   995  C  CB  . ARG A 1 126 ? -19.011 -16.378 1.997   1   41.04  ? 122 ARG A CB  1 
ATOM   996  C  CG  . ARG A 1 126 ? -19.688 -15.338 2.882   1   38.06  ? 122 ARG A CG  1 
ATOM   997  C  CD  . ARG A 1 126 ? -18.813 -14.158 3.215   1   40.76  ? 122 ARG A CD  1 
ATOM   998  N  NE  . ARG A 1 126 ? -19.565 -13.15  3.979   1   58.12  ? 122 ARG A NE  1 
ATOM   999  C  CZ  . ARG A 1 126 ? -20.059 -13.284 5.235   1   54.9   ? 122 ARG A CZ  1 
ATOM   1000 N  NH1 . ARG A 1 126 ? -19.874 -14.395 5.952   1   46.63  ? 122 ARG A NH1 1 
ATOM   1001 N  NH2 . ARG A 1 126 ? -20.732 -12.28  5.772   1   49.01  ? 122 ARG A NH2 1 
ATOM   1002 N  N   . VAL A 1 127 ? -16.625 -18.16  4.403   1   40.07  ? 123 VAL A N   1 
ATOM   1003 C  CA  . VAL A 1 127 ? -15.393 -18.013 5.185   1   40.67  ? 123 VAL A CA  1 
ATOM   1004 C  C   . VAL A 1 127 ? -14.376 -19.124 4.871   1   41.97  ? 123 VAL A C   1 
ATOM   1005 O  O   . VAL A 1 127 ? -14.679 -20.314 5.009   1   41.88  ? 123 VAL A O   1 
ATOM   1006 C  CB  . VAL A 1 127 ? -15.697 -17.939 6.701   1   41.48  ? 123 VAL A CB  1 
ATOM   1007 C  CG1 . VAL A 1 127 ? -14.433 -17.916 7.575   1   35.66  ? 123 VAL A CG1 1 
ATOM   1008 C  CG2 . VAL A 1 127 ? -16.597 -16.744 7.01    1   42.47  ? 123 VAL A CG2 1 
ATOM   1009 N  N   . LEU A 1 128 ? -13.153 -18.73  4.472   1   39.29  ? 124 LEU A N   1 
ATOM   1010 C  CA  . LEU A 1 128 ? -12.01  -19.628 4.354   1   36.18  ? 124 LEU A CA  1 
ATOM   1011 C  C   . LEU A 1 128 ? -11.24  -19.544 5.661   1   39.27  ? 124 LEU A C   1 
ATOM   1012 O  O   . LEU A 1 128 ? -11.014 -18.452 6.177   1   46.05  ? 124 LEU A O   1 
ATOM   1013 C  CB  . LEU A 1 128 ? -11.061 -19.199 3.236   1   38.01  ? 124 LEU A CB  1 
ATOM   1014 C  CG  . LEU A 1 128 ? -11.575 -19.224 1.8     1   38.25  ? 124 LEU A CG  1 
ATOM   1015 C  CD1 . LEU A 1 128 ? -10.466 -18.826 0.837   1   36.35  ? 124 LEU A CD1 1 
ATOM   1016 C  CD2 . LEU A 1 128 ? -12.073 -20.63  1.507   1   38.56  ? 124 LEU A CD2 1 
ATOM   1017 N  N   . HIS A 1 129 ? -10.793 -20.691 6.161   1   38.23  ? 125 HIS A N   1 
ATOM   1018 C  CA  . HIS A 1 129 ? -10.089 -20.709 7.424   1   41.49  ? 125 HIS A CA  1 
ATOM   1019 C  C   . HIS A 1 129 ? -8.626  -20.327 7.217   1   43.42  ? 125 HIS A C   1 
ATOM   1020 O  O   . HIS A 1 129 ? -8.114  -19.412 7.865   1   40.46  ? 125 HIS A O   1 
ATOM   1021 C  CB  . HIS A 1 129 ? -10.228 -22.067 8.101   1   38.78  ? 125 HIS A CB  1 
ATOM   1022 C  CG  . HIS A 1 129 ? -9.691  -22.034 9.481   1   43.45  ? 125 HIS A CG  1 
ATOM   1023 N  ND1 . HIS A 1 129 ? -8.331  -22.061 9.686   1   43.03  ? 125 HIS A ND1 1 
ATOM   1024 C  CD2 . HIS A 1 129 ? -10.257 -21.927 10.696  1   47.36  ? 125 HIS A CD2 1 
ATOM   1025 C  CE1 . HIS A 1 129 ? -8.084  -22.016 10.989  1   48.17  ? 125 HIS A CE1 1 
ATOM   1026 N  NE2 . HIS A 1 129 ? -9.235  -21.947 11.631  1   48.51  ? 125 HIS A NE2 1 
ATOM   1027 N  N   . ARG A 1 130 ? -7.953  -21.089 6.35    1   44.61  ? 126 ARG A N   1 
ATOM   1028 C  CA  . ARG A 1 130 ? -6.616  -20.755 5.869   1   48     ? 126 ARG A CA  1 
ATOM   1029 C  C   . ARG A 1 130 ? -5.508  -21.042 6.892   1   47.79  ? 126 ARG A C   1 
ATOM   1030 O  O   . ARG A 1 130 ? -4.379  -20.64  6.666   1   52.74  ? 126 ARG A O   1 
ATOM   1031 C  CB  . ARG A 1 130 ? -6.542  -19.321 5.335   1   41.35  ? 126 ARG A CB  1 
ATOM   1032 C  CG  . ARG A 1 130 ? -7.418  -19.095 4.108   1   43.55  ? 126 ARG A CG  1 
ATOM   1033 C  CD  . ARG A 1 130 ? -7.084  -17.802 3.388   1   42.71  ? 126 ARG A CD  1 
ATOM   1034 N  NE  . ARG A 1 130 ? -7.083  -16.692 4.346   1   43.8   ? 126 ARG A NE  1 
ATOM   1035 C  CZ  . ARG A 1 130 ? -6.704  -15.44  4.057   1   46.61  ? 126 ARG A CZ  1 
ATOM   1036 N  NH1 . ARG A 1 130 ? -6.36   -15.099 2.831   1   42.21  ? 126 ARG A NH1 1 
ATOM   1037 N  NH2 . ARG A 1 130 ? -6.666  -14.52  5.002   1   44.2   ? 126 ARG A NH2 1 
ATOM   1038 N  N   . ASP A 1 131 ? -5.789  -21.768 7.985   1   45.73  ? 127 ASP A N   1 
ATOM   1039 C  CA  . ASP A 1 131 ? -4.74   -22.236 8.88    1   46.29  ? 127 ASP A CA  1 
ATOM   1040 C  C   . ASP A 1 131 ? -5.182  -23.521 9.588   1   49.21  ? 127 ASP A C   1 
ATOM   1041 O  O   . ASP A 1 131 ? -4.951  -23.669 10.794  1   48.06  ? 127 ASP A O   1 
ATOM   1042 C  CB  . ASP A 1 131 ? -4.269  -21.179 9.879   1   40.87  ? 127 ASP A CB  1 
ATOM   1043 C  CG  . ASP A 1 131 ? -2.826  -21.336 10.354  1   45.45  ? 127 ASP A CG  1 
ATOM   1044 O  OD1 . ASP A 1 131 ? -2.052  -22.06  9.689   1   58     ? 127 ASP A OD1 1 
ATOM   1045 O  OD2 . ASP A 1 131 ? -2.463  -20.751 11.385  1   54.88  ? 127 ASP A OD2 1 
ATOM   1046 N  N   . LEU A 1 132 ? -5.783  -24.468 8.851   1   41.17  ? 128 LEU A N   1 
ATOM   1047 C  CA  . LEU A 1 132 ? -6.135  -25.715 9.512   1   42.8   ? 128 LEU A CA  1 
ATOM   1048 C  C   . LEU A 1 132 ? -4.878  -26.566 9.755   1   45.33  ? 128 LEU A C   1 
ATOM   1049 O  O   . LEU A 1 132 ? -4.095  -26.869 8.853   1   49.02  ? 128 LEU A O   1 
ATOM   1050 C  CB  . LEU A 1 132 ? -7.2    -26.398 8.672   1   45.54  ? 128 LEU A CB  1 
ATOM   1051 C  CG  . LEU A 1 132 ? -8.499  -25.608 8.521   1   47.6   ? 128 LEU A CG  1 
ATOM   1052 C  CD1 . LEU A 1 132 ? -9.379  -26.265 7.454   1   41.62  ? 128 LEU A CD1 1 
ATOM   1053 C  CD2 . LEU A 1 132 ? -9.207  -25.476 9.888   1   39.29  ? 128 LEU A CD2 1 
ATOM   1054 N  N   . LYS A 1 133 ? -4.643  -26.869 11.03   1   41.56  ? 129 LYS A N   1 
ATOM   1055 C  CA  . LYS A 1 133 ? -3.539  -27.688 11.494  1   40.41  ? 129 LYS A CA  1 
ATOM   1056 C  C   . LYS A 1 133 ? -3.896  -28.156 12.899  1   43.23  ? 129 LYS A C   1 
ATOM   1057 O  O   . LYS A 1 133 ? -4.747  -27.559 13.566  1   45.34  ? 129 LYS A O   1 
ATOM   1058 C  CB  . LYS A 1 133 ? -2.229  -26.889 11.518  1   39.82  ? 129 LYS A CB  1 
ATOM   1059 C  CG  . LYS A 1 133 ? -2.295  -25.62  12.366  1   39.04  ? 129 LYS A CG  1 
ATOM   1060 C  CD  . LYS A 1 133 ? -1.011  -24.813 12.342  1   41.78  ? 129 LYS A CD  1 
ATOM   1061 C  CE  . LYS A 1 133 ? -1.063  -23.609 13.23   1   47.74  ? 129 LYS A CE  1 
ATOM   1062 N  NZ  . LYS A 1 133 ? 0.176   -22.824 13.129  1   46.35  ? 129 LYS A NZ  1 
ATOM   1063 N  N   . PRO A 1 134 ? -3.257  -29.228 13.407  1   46.18  ? 130 PRO A N   1 
ATOM   1064 C  CA  . PRO A 1 134 ? -3.693  -29.855 14.662  1   46.69  ? 130 PRO A CA  1 
ATOM   1065 C  C   . PRO A 1 134 ? -3.727  -28.965 15.902  1   47.33  ? 130 PRO A C   1 
ATOM   1066 O  O   . PRO A 1 134 ? -4.551  -29.188 16.785  1   52.84  ? 130 PRO A O   1 
ATOM   1067 C  CB  . PRO A 1 134 ? -2.711  -31.015 14.819  1   43.27  ? 130 PRO A CB  1 
ATOM   1068 C  CG  . PRO A 1 134 ? -2.224  -31.28  13.427  1   42.08  ? 130 PRO A CG  1 
ATOM   1069 C  CD  . PRO A 1 134 ? -2.114  -29.909 12.783  1   42.5   ? 130 PRO A CD  1 
ATOM   1070 N  N   . GLN A 1 135 ? -2.816  -27.986 15.948  1   47.07  ? 131 GLN A N   1 
ATOM   1071 C  CA  . GLN A 1 135 ? -2.667  -26.975 16.986  1   48.1   ? 131 GLN A CA  1 
ATOM   1072 C  C   . GLN A 1 135 ? -3.922  -26.106 17.094  1   48.96  ? 131 GLN A C   1 
ATOM   1073 O  O   . GLN A 1 135 ? -4.202  -25.576 18.168  1   57.03  ? 131 GLN A O   1 
ATOM   1074 C  CB  . GLN A 1 135 ? -1.487  -26.055 16.646  1   54.18  ? 131 GLN A CB  1 
ATOM   1075 C  CG  . GLN A 1 135 ? -0.088  -26.674 16.771  1   63.24  ? 131 GLN A CG  1 
ATOM   1076 C  CD  . GLN A 1 135 ? 0.39    -27.535 15.605  1   76.31  ? 131 GLN A CD  1 
ATOM   1077 O  OE1 . GLN A 1 135 ? -0.296  -27.786 14.6    1   64.92  ? 131 GLN A OE1 1 
ATOM   1078 N  NE2 . GLN A 1 135 ? 1.611   -28.038 15.734  1   86.9   ? 131 GLN A NE2 1 
ATOM   1079 N  N   . ASN A 1 136 ? -4.652  -25.944 15.979  1   43.98  ? 132 ASN A N   1 
ATOM   1080 C  CA  . ASN A 1 136 ? -5.8    -25.054 15.849  1   40.15  ? 132 ASN A CA  1 
ATOM   1081 C  C   . ASN A 1 136 ? -7.109  -25.841 15.857  1   42.28  ? 132 ASN A C   1 
ATOM   1082 O  O   . ASN A 1 136 ? -8.158  -25.287 15.524  1   43.21  ? 132 ASN A O   1 
ATOM   1083 C  CB  . ASN A 1 136 ? -5.74   -24.259 14.546  1   38.9   ? 132 ASN A CB  1 
ATOM   1084 C  CG  . ASN A 1 136 ? -4.701  -23.17  14.614  1   45.07  ? 132 ASN A CG  1 
ATOM   1085 O  OD1 . ASN A 1 136 ? -4.31   -22.797 15.714  1   50.37  ? 132 ASN A OD1 1 
ATOM   1086 N  ND2 . ASN A 1 136 ? -4.239  -22.645 13.489  1   43.14  ? 132 ASN A ND2 1 
ATOM   1087 N  N   . LEU A 1 137 ? -7.048  -27.129 16.234  1   41.34  ? 133 LEU A N   1 
ATOM   1088 C  CA  . LEU A 1 137 ? -8.252  -27.907 16.47   1   40.14  ? 133 LEU A CA  1 
ATOM   1089 C  C   . LEU A 1 137 ? -8.351  -28.283 17.958  1   43.25  ? 133 LEU A C   1 
ATOM   1090 O  O   . LEU A 1 137 ? -7.512  -29.003 18.491  1   46.15  ? 133 LEU A O   1 
ATOM   1091 C  CB  . LEU A 1 137 ? -8.194  -29.124 15.551  1   41.19  ? 133 LEU A CB  1 
ATOM   1092 C  CG  . LEU A 1 137 ? -7.855  -28.86  14.079  1   41.19  ? 133 LEU A CG  1 
ATOM   1093 C  CD1 . LEU A 1 137 ? -7.951  -30.155 13.269  1   42.62  ? 133 LEU A CD1 1 
ATOM   1094 C  CD2 . LEU A 1 137 ? -8.796  -27.853 13.49   1   35.74  ? 133 LEU A CD2 1 
ATOM   1095 N  N   . LEU A 1 138 ? -9.416  -27.827 18.628  1   40.87  ? 134 LEU A N   1 
ATOM   1096 C  CA  . LEU A 1 138 ? -9.579  -27.998 20.062  1   43.65  ? 134 LEU A CA  1 
ATOM   1097 C  C   . LEU A 1 138 ? -10.545 -29.142 20.376  1   45.5   ? 134 LEU A C   1 
ATOM   1098 O  O   . LEU A 1 138 ? -11.584 -29.279 19.745  1   50.74  ? 134 LEU A O   1 
ATOM   1099 C  CB  . LEU A 1 138 ? -10.055 -26.652 20.616  1   42.08  ? 134 LEU A CB  1 
ATOM   1100 C  CG  . LEU A 1 138 ? -9.125  -25.462 20.338  1   46.31  ? 134 LEU A CG  1 
ATOM   1101 C  CD1 . LEU A 1 138 ? -9.648  -24.193 20.975  1   45.92  ? 134 LEU A CD1 1 
ATOM   1102 C  CD2 . LEU A 1 138 ? -7.688  -25.68  20.8    1   46.8   ? 134 LEU A CD2 1 
ATOM   1103 N  N   . ILE A 1 139 ? -10.188 -29.969 21.359  1   44.58  ? 135 ILE A N   1 
ATOM   1104 C  CA  . ILE A 1 139 ? -10.994 -31.099 21.79   1   44.62  ? 135 ILE A CA  1 
ATOM   1105 C  C   . ILE A 1 139 ? -11.45  -30.855 23.224  1   47.21  ? 135 ILE A C   1 
ATOM   1106 O  O   . ILE A 1 139 ? -10.757 -30.219 24.008  1   48.18  ? 135 ILE A O   1 
ATOM   1107 C  CB  . ILE A 1 139 ? -10.217 -32.427 21.645  1   45.92  ? 135 ILE A CB  1 
ATOM   1108 C  CG1 . ILE A 1 139 ? -8.985  -32.519 22.526  1   56.33  ? 135 ILE A CG1 1 
ATOM   1109 C  CG2 . ILE A 1 139 ? -9.826  -32.688 20.193  1   42.49  ? 135 ILE A CG2 1 
ATOM   1110 C  CD1 . ILE A 1 139 ? -8.185  -33.791 22.295  1   57.8   ? 135 ILE A CD1 1 
ATOM   1111 N  N   . ASN A 1 140 ? -12.648 -31.326 23.569  1   52.65  ? 136 ASN A N   1 
ATOM   1112 C  CA  . ASN A 1 140 ? -13.105 -31.221 24.95   1   51.76  ? 136 ASN A CA  1 
ATOM   1113 C  C   . ASN A 1 140 ? -13.148 -32.61  25.578  1   55.25  ? 136 ASN A C   1 
ATOM   1114 O  O   . ASN A 1 140 ? -12.669 -33.567 24.976  1   63.88  ? 136 ASN A O   1 
ATOM   1115 C  CB  . ASN A 1 140 ? -14.422 -30.461 25.069  1   48.7   ? 136 ASN A CB  1 
ATOM   1116 C  CG  . ASN A 1 140 ? -15.581 -31.169 24.414  1   49.2   ? 136 ASN A CG  1 
ATOM   1117 O  OD1 . ASN A 1 140 ? -15.537 -32.39  24.161  1   49.75  ? 136 ASN A OD1 1 
ATOM   1118 N  ND2 . ASN A 1 140 ? -16.637 -30.405 24.176  1   44.45  ? 136 ASN A ND2 1 
ATOM   1119 N  N   . THR A 1 141 ? -13.701 -32.697 26.79   1   56.94  ? 137 THR A N   1 
ATOM   1120 C  CA  . THR A 1 141 ? -13.77  -33.973 27.487  1   62.11  ? 137 THR A CA  1 
ATOM   1121 C  C   . THR A 1 141 ? -14.96  -34.786 26.967  1   65.81  ? 137 THR A C   1 
ATOM   1122 O  O   . THR A 1 141 ? -15.059 -35.955 27.29   1   76.48  ? 137 THR A O   1 
ATOM   1123 C  CB  . THR A 1 141 ? -13.796 -33.799 29.013  1   59.73  ? 137 THR A CB  1 
ATOM   1124 O  OG1 . THR A 1 141 ? -14.722 -32.759 29.311  1   55.97  ? 137 THR A OG1 1 
ATOM   1125 C  CG2 . THR A 1 141 ? -12.472 -33.357 29.608  1   56.52  ? 137 THR A CG2 1 
ATOM   1126 N  N   . GLU A 1 142 ? -15.834 -34.196 26.143  1   63.73  ? 138 GLU A N   1 
ATOM   1127 C  CA  . GLU A 1 142 ? -17.061 -34.861 25.739  1   65.77  ? 138 GLU A CA  1 
ATOM   1128 C  C   . GLU A 1 142 ? -16.884 -35.556 24.392  1   63.22  ? 138 GLU A C   1 
ATOM   1129 O  O   . GLU A 1 142 ? -17.8   -36.247 23.942  1   64.29  ? 138 GLU A O   1 
ATOM   1130 C  CB  . GLU A 1 142 ? -18.217 -33.854 25.71   1   70.68  ? 138 GLU A CB  1 
ATOM   1131 C  CG  . GLU A 1 142 ? -18.723 -33.468 27.095  1   72.67  ? 138 GLU A CG  1 
ATOM   1132 C  CD  . GLU A 1 142 ? -19.561 -34.597 27.674  1   81.87  ? 138 GLU A CD  1 
ATOM   1133 O  OE1 . GLU A 1 142 ? -20.634 -34.934 27.127  1   80.83  ? 138 GLU A OE1 1 
ATOM   1134 O  OE2 . GLU A 1 142 ? -19.129 -35.157 28.693  1   91.52  ? 138 GLU A OE2 1 
ATOM   1135 N  N   . GLY A 1 143 ? -15.724 -35.343 23.759  1   60.12  ? 139 GLY A N   1 
ATOM   1136 C  CA  . GLY A 1 143 ? -15.367 -35.989 22.504  1   54.89  ? 139 GLY A CA  1 
ATOM   1137 C  C   . GLY A 1 143 ? -15.615 -35.091 21.3    1   54.71  ? 139 GLY A C   1 
ATOM   1138 O  O   . GLY A 1 143 ? -15.537 -35.552 20.162  1   57.59  ? 139 GLY A O   1 
ATOM   1139 N  N   . ALA A 1 144 ? -15.918 -33.811 21.562  1   51.13  ? 140 ALA A N   1 
ATOM   1140 C  CA  . ALA A 1 144 ? -16.103 -32.829 20.499  1   45.9   ? 140 ALA A CA  1 
ATOM   1141 C  C   . ALA A 1 144 ? -14.74  -32.359 20.002  1   44.71  ? 140 ALA A C   1 
ATOM   1142 O  O   . ALA A 1 144 ? -13.78  -32.366 20.759  1   49.14  ? 140 ALA A O   1 
ATOM   1143 C  CB  . ALA A 1 144 ? -16.885 -31.654 21.059  1   46.42  ? 140 ALA A CB  1 
ATOM   1144 N  N   . ILE A 1 145 ? -14.668 -31.908 18.75   1   44.8   ? 141 ILE A N   1 
ATOM   1145 C  CA  . ILE A 1 145 ? -13.477 -31.255 18.22   1   45.94  ? 141 ILE A CA  1 
ATOM   1146 C  C   . ILE A 1 145 ? -13.949 -30.05  17.405  1   44.52  ? 141 ILE A C   1 
ATOM   1147 O  O   . ILE A 1 145 ? -14.989 -30.12  16.747  1   42.63  ? 141 ILE A O   1 
ATOM   1148 C  CB  . ILE A 1 145 ? -12.607 -32.234 17.403  1   47.01  ? 141 ILE A CB  1 
ATOM   1149 C  CG1 . ILE A 1 145 ? -11.25  -31.632 17.009  1   48.4   ? 141 ILE A CG1 1 
ATOM   1150 C  CG2 . ILE A 1 145 ? -13.368 -32.724 16.168  1   47.95  ? 141 ILE A CG2 1 
ATOM   1151 C  CD1 . ILE A 1 145 ? -10.273 -32.617 16.402  1   42.77  ? 141 ILE A CD1 1 
ATOM   1152 N  N   . LYS A 1 146 ? -13.195 -28.939 17.466  1   44.84  ? 142 LYS A N   1 
ATOM   1153 C  CA  . LYS A 1 146 ? -13.733 -27.67  16.998  1   41.89  ? 142 LYS A CA  1 
ATOM   1154 C  C   . LYS A 1 146 ? -12.642 -26.865 16.324  1   42.51  ? 142 LYS A C   1 
ATOM   1155 O  O   . LYS A 1 146 ? -11.558 -26.762 16.887  1   48.96  ? 142 LYS A O   1 
ATOM   1156 C  CB  . LYS A 1 146 ? -14.272 -26.873 18.191  1   41.13  ? 142 LYS A CB  1 
ATOM   1157 C  CG  . LYS A 1 146 ? -15.314 -27.644 19.005  1   45.2   ? 142 LYS A CG  1 
ATOM   1158 C  CD  . LYS A 1 146 ? -16.273 -26.778 19.818  1   46.93  ? 142 LYS A CD  1 
ATOM   1159 C  CE  . LYS A 1 146 ? -17.131 -27.648 20.695  1   44.4   ? 142 LYS A CE  1 
ATOM   1160 N  NZ  . LYS A 1 146 ? -18.295 -26.895 21.149  1   40.31  ? 142 LYS A NZ  1 
ATOM   1161 N  N   . LEU A 1 147 ? -12.953 -26.307 15.144  1   42.23  ? 143 LEU A N   1 
ATOM   1162 C  CA  . LEU A 1 147 ? -12.056 -25.394 14.451  1   41.28  ? 143 LEU A CA  1 
ATOM   1163 C  C   . LEU A 1 147 ? -11.871 -24.182 15.348  1   43.23  ? 143 LEU A C   1 
ATOM   1164 O  O   . LEU A 1 147 ? -12.842 -23.619 15.854  1   43.65  ? 143 LEU A O   1 
ATOM   1165 C  CB  . LEU A 1 147 ? -12.551 -24.925 13.081  1   42.91  ? 143 LEU A CB  1 
ATOM   1166 C  CG  . LEU A 1 147 ? -13.232 -25.958 12.178  1   43.74  ? 143 LEU A CG  1 
ATOM   1167 C  CD1 . LEU A 1 147 ? -13.204 -25.406 10.787  1   44.73  ? 143 LEU A CD1 1 
ATOM   1168 C  CD2 . LEU A 1 147 ? -12.64  -27.339 12.214  1   38.28  ? 143 LEU A CD2 1 
ATOM   1169 N  N   . ALA A 1 148 ? -10.609 -23.79  15.503  1   42.4   ? 144 ALA A N   1 
ATOM   1170 C  CA  . ALA A 1 148 ? -10.262 -22.623 16.296  1   43.42  ? 144 ALA A CA  1 
ATOM   1171 C  C   . ALA A 1 148 ? -9.243  -21.799 15.52   1   41.7   ? 144 ALA A C   1 
ATOM   1172 O  O   . ALA A 1 148 ? -8.735  -22.252 14.493  1   43.7   ? 144 ALA A O   1 
ATOM   1173 C  CB  . ALA A 1 148 ? -9.765  -23.033 17.676  1   37.85  ? 144 ALA A CB  1 
ATOM   1174 N  N   . ASP A 1 149 ? -9.031  -20.581 16.015  1   42.78  ? 145 ASP A N   1 
ATOM   1175 C  CA  . ASP A 1 149 ? -8.055  -19.605 15.56   1   50.61  ? 145 ASP A CA  1 
ATOM   1176 C  C   . ASP A 1 149 ? -8.38   -19.106 14.163  1   47.2   ? 145 ASP A C   1 
ATOM   1177 O  O   . ASP A 1 149 ? -7.766  -19.56  13.204  1   49.16  ? 145 ASP A O   1 
ATOM   1178 C  CB  . ASP A 1 149 ? -6.6    -20.032 15.697  1   50.44  ? 145 ASP A CB  1 
ATOM   1179 C  CG  . ASP A 1 149 ? -5.637  -18.851 15.585  1   69.55  ? 145 ASP A CG  1 
ATOM   1180 O  OD1 . ASP A 1 149 ? -6.098  -17.662 15.511  1   64.32  ? 145 ASP A OD1 1 
ATOM   1181 O  OD2 . ASP A 1 149 ? -4.423  -19.108 15.65   1   85.19  ? 145 ASP A OD2 1 
ATOM   1182 N  N   . PHE A 1 150 ? -9.246  -18.093 14.101  1   44.58  ? 146 PHE A N   1 
ATOM   1183 C  CA  . PHE A 1 150 ? -9.713  -17.534 12.838  1   49.32  ? 146 PHE A CA  1 
ATOM   1184 C  C   . PHE A 1 150 ? -9.004  -16.208 12.526  1   51.21  ? 146 PHE A C   1 
ATOM   1185 O  O   . PHE A 1 150 ? -9.585  -15.347 11.856  1   49.88  ? 146 PHE A O   1 
ATOM   1186 C  CB  . PHE A 1 150 ? -11.245 -17.418 12.889  1   46.27  ? 146 PHE A CB  1 
ATOM   1187 C  CG  . PHE A 1 150 ? -12.02  -18.719 12.733  1   42.67  ? 146 PHE A CG  1 
ATOM   1188 C  CD1 . PHE A 1 150 ? -11.994 -19.687 13.734  1   43.64  ? 146 PHE A CD1 1 
ATOM   1189 C  CD2 . PHE A 1 150 ? -12.784 -18.967 11.6    1   40.99  ? 146 PHE A CD2 1 
ATOM   1190 C  CE1 . PHE A 1 150 ? -12.684 -20.878 13.608  1   40.31  ? 146 PHE A CE1 1 
ATOM   1191 C  CE2 . PHE A 1 150 ? -13.483 -20.161 11.478  1   39.85  ? 146 PHE A CE2 1 
ATOM   1192 C  CZ  . PHE A 1 150 ? -13.449 -21.094 12.489  1   38.97  ? 146 PHE A CZ  1 
ATOM   1193 N  N   . GLY A 1 151 ? -7.742  -16.067 12.979  1   48.49  ? 147 GLY A N   1 
ATOM   1194 C  CA  . GLY A 1 151 ? -6.977  -14.834 12.803  1   54.15  ? 147 GLY A CA  1 
ATOM   1195 C  C   . GLY A 1 151 ? -6.427  -14.705 11.384  1   53.3   ? 147 GLY A C   1 
ATOM   1196 O  O   . GLY A 1 151 ? -6.098  -13.604 10.963  1   53.97  ? 147 GLY A O   1 
ATOM   1197 N  N   . LEU A 1 152 ? -6.363  -15.839 10.671  1   52.53  ? 148 LEU A N   1 
ATOM   1198 C  CA  . LEU A 1 152 ? -5.87   -15.92  9.307   1   55.08  ? 148 LEU A CA  1 
ATOM   1199 C  C   . LEU A 1 152 ? -7.009  -16.158 8.322   1   46.94  ? 148 LEU A C   1 
ATOM   1200 O  O   . LEU A 1 152 ? -6.76   -16.373 7.143   1   51.14  ? 148 LEU A O   1 
ATOM   1201 C  CB  . LEU A 1 152 ? -4.805  -17.01  9.235   1   58.16  ? 148 LEU A CB  1 
ATOM   1202 C  CG  . LEU A 1 152 ? -3.488  -16.612 9.905   1   75.01  ? 148 LEU A CG  1 
ATOM   1203 C  CD1 . LEU A 1 152 ? -2.539  -17.775 9.979   1   88.81  ? 148 LEU A CD1 1 
ATOM   1204 C  CD2 . LEU A 1 152 ? -2.844  -15.461 9.162   1   71.08  ? 148 LEU A CD2 1 
ATOM   1205 N  N   . ALA A 1 153 ? -8.246  -16.033 8.799   1   43.71  ? 149 ALA A N   1 
ATOM   1206 C  CA  . ALA A 1 153 ? -9.427  -16.369 8.015   1   43.55  ? 149 ALA A CA  1 
ATOM   1207 C  C   . ALA A 1 153 ? -9.869  -15.185 7.159   1   45.84  ? 149 ALA A C   1 
ATOM   1208 O  O   . ALA A 1 153 ? -9.38   -14.057 7.357   1   48.22  ? 149 ALA A O   1 
ATOM   1209 C  CB  . ALA A 1 153 ? -10.519 -16.809 8.95    1   41.69  ? 149 ALA A CB  1 
ATOM   1210 N  N   . ARG A 1 154 ? -10.799 -15.451 6.222   1   41.07  ? 150 ARG A N   1 
ATOM   1211 C  CA  . ARG A 1 154 ? -11.156 -14.439 5.229   1   48.65  ? 150 ARG A CA  1 
ATOM   1212 C  C   . ARG A 1 154 ? -12.566 -14.656 4.68    1   50.41  ? 150 ARG A C   1 
ATOM   1213 O  O   . ARG A 1 154 ? -12.923 -15.764 4.228   1   49.2   ? 150 ARG A O   1 
ATOM   1214 C  CB  . ARG A 1 154 ? -10.182 -14.426 4.039   1   46.4   ? 150 ARG A CB  1 
ATOM   1215 C  CG  . ARG A 1 154 ? -10.397 -13.389 2.942   1   49.47  ? 150 ARG A CG  1 
ATOM   1216 C  CD  . ARG A 1 154 ? -9.464  -12.26  3.227   1   55.37  ? 150 ARG A CD  1 
ATOM   1217 N  NE  . ARG A 1 154 ? -8.827  -11.773 2.003   1   54.85  ? 150 ARG A NE  1 
ATOM   1218 C  CZ  . ARG A 1 154 ? -8.999  -10.569 1.505   1   53.19  ? 150 ARG A CZ  1 
ATOM   1219 N  NH1 . ARG A 1 154 ? -7.941  -9.865  1.168   1   49.95  ? 150 ARG A NH1 1 
ATOM   1220 N  NH2 . ARG A 1 154 ? -10.188 -9.997  1.518   1   58.19  ? 150 ARG A NH2 1 
ATOM   1221 N  N   . ALA A 1 155 ? -13.325 -13.551 4.626   1   41.46  ? 151 ALA A N   1 
ATOM   1222 C  CA  . ALA A 1 155 ? -14.601 -13.619 3.931   1   41.45  ? 151 ALA A CA  1 
ATOM   1223 C  C   . ALA A 1 155 ? -14.391 -13.53  2.42    1   41.39  ? 151 ALA A C   1 
ATOM   1224 O  O   . ALA A 1 155 ? -13.784 -12.585 1.94    1   43.28  ? 151 ALA A O   1 
ATOM   1225 C  CB  . ALA A 1 155 ? -15.532 -12.562 4.443   1   37.73  ? 151 ALA A CB  1 
ATOM   1226 N  N   . PHE A 1 156 ? -14.899 -14.521 1.682   1   40.82  ? 152 PHE A N   1 
ATOM   1227 C  CA  . PHE A 1 156 ? -14.683 -14.566 0.244   1   44.02  ? 152 PHE A CA  1 
ATOM   1228 C  C   . PHE A 1 156 ? -15.939 -14.153 -0.522  1   45.98  ? 152 PHE A C   1 
ATOM   1229 O  O   . PHE A 1 156 ? -17.059 -14.212 0.005   1   50.25  ? 152 PHE A O   1 
ATOM   1230 C  CB  . PHE A 1 156 ? -14.121 -15.923 -0.202  1   47.23  ? 152 PHE A CB  1 
ATOM   1231 C  CG  . PHE A 1 156 ? -14.967 -17.183 -0.041  1   44.17  ? 152 PHE A CG  1 
ATOM   1232 C  CD1 . PHE A 1 156 ? -15.786 -17.624 -1.079  1   44.55  ? 152 PHE A CD1 1 
ATOM   1233 C  CD2 . PHE A 1 156 ? -14.898 -17.953 1.116   1   42.02  ? 152 PHE A CD2 1 
ATOM   1234 C  CE1 . PHE A 1 156 ? -16.516 -18.802 -0.966  1   44.01  ? 152 PHE A CE1 1 
ATOM   1235 C  CE2 . PHE A 1 156 ? -15.658 -19.114 1.245   1   41.81  ? 152 PHE A CE2 1 
ATOM   1236 C  CZ  . PHE A 1 156 ? -16.446 -19.552 0.199   1   42.87  ? 152 PHE A CZ  1 
ATOM   1237 N  N   . GLY A 1 157 ? -15.708 -13.697 -1.765  1   46.59  ? 153 GLY A N   1 
ATOM   1238 C  CA  . GLY A 1 157 ? -16.741 -13.443 -2.758  1   43.41  ? 153 GLY A CA  1 
ATOM   1239 C  C   . GLY A 1 157 ? -16.81  -14.591 -3.763  1   43.89  ? 153 GLY A C   1 
ATOM   1240 O  O   . GLY A 1 157 ? -15.876 -15.385 -3.852  1   42.99  ? 153 GLY A O   1 
ATOM   1241 N  N   . VAL A 1 158 ? -17.924 -14.669 -4.503  1   43.3   ? 154 VAL A N   1 
ATOM   1242 C  CA  . VAL A 1 158 ? -18.149 -15.734 -5.465  1   42.26  ? 154 VAL A CA  1 
ATOM   1243 C  C   . VAL A 1 158 ? -18.261 -15.09  -6.845  1   41.47  ? 154 VAL A C   1 
ATOM   1244 O  O   . VAL A 1 158 ? -19.111 -14.224 -7.013  1   38.82  ? 154 VAL A O   1 
ATOM   1245 C  CB  . VAL A 1 158 ? -19.423 -16.524 -5.099  1   44.66  ? 154 VAL A CB  1 
ATOM   1246 C  CG1 . VAL A 1 158 ? -19.71  -17.603 -6.132  1   47.78  ? 154 VAL A CG1 1 
ATOM   1247 C  CG2 . VAL A 1 158 ? -19.291 -17.179 -3.729  1   44.44  ? 154 VAL A CG2 1 
ATOM   1248 N  N   . PRO A 1 159 ? -17.355 -15.377 -7.827  1   40.88  ? 155 PRO A N   1 
ATOM   1249 C  CA  . PRO A 1 159 ? -16.135 -16.155 -7.6    1   40.72  ? 155 PRO A CA  1 
ATOM   1250 C  C   . PRO A 1 159 ? -15.115 -15.373 -6.771  1   48.55  ? 155 PRO A C   1 
ATOM   1251 O  O   . PRO A 1 159 ? -15.238 -14.144 -6.646  1   50.16  ? 155 PRO A O   1 
ATOM   1252 C  CB  . PRO A 1 159 ? -15.593 -16.432 -9.007  1   39.23  ? 155 PRO A CB  1 
ATOM   1253 C  CG  . PRO A 1 159 ? -16.129 -15.327 -9.868  1   38.93  ? 155 PRO A CG  1 
ATOM   1254 C  CD  . PRO A 1 159 ? -17.43  -14.869 -9.211  1   42.48  ? 155 PRO A CD  1 
ATOM   1255 N  N   . VAL A 1 160 ? -14.132 -16.11  -6.211  1   46.49  ? 156 VAL A N   1 
ATOM   1256 C  CA  . VAL A 1 160 ? -13.057 -15.559 -5.395  1   43.71  ? 156 VAL A CA  1 
ATOM   1257 C  C   . VAL A 1 160 ? -12.191 -14.617 -6.236  1   47.07  ? 156 VAL A C   1 
ATOM   1258 O  O   . VAL A 1 160 ? -12.071 -14.739 -7.456  1   44.17  ? 156 VAL A O   1 
ATOM   1259 C  CB  . VAL A 1 160 ? -12.179 -16.638 -4.735  1   41.73  ? 156 VAL A CB  1 
ATOM   1260 C  CG1 . VAL A 1 160 ? -12.958 -17.473 -3.73   1   43.35  ? 156 VAL A CG1 1 
ATOM   1261 C  CG2 . VAL A 1 160 ? -11.508 -17.532 -5.774  1   40.55  ? 156 VAL A CG2 1 
ATOM   1262 N  N   . ARG A 1 161 ? -11.592 -13.651 -5.375  1   49.14  ? 157 ARG A N   1 
ATOM   1263 C  CA  . ARG A 1 161 ? -10.633 -12.693 -5.963  1   53.97  ? 157 ARG A CA  1 
ATOM   1264 C  C   . ARG A 1 161 ? -9.24   -13.187 -5.557  1   53.59  ? 157 ARG A C   1 
ATOM   1265 O  O   . ARG A 1 161 ? -9.152  -14.268 -4.954  1   48.36  ? 157 ARG A O   1 
ATOM   1266 C  CB  . ARG A 1 161 ? -10.821 -11.291 -5.383  1   57.58  ? 157 ARG A CB  1 
ATOM   1267 C  CG  . ARG A 1 161 ? -11.832 -10.373 -6.048  1   69.44  ? 157 ARG A CG  1 
ATOM   1268 C  CD  . ARG A 1 161 ? -11.862 -9.045  -5.31   1   74.48  ? 157 ARG A CD  1 
ATOM   1269 N  NE  . ARG A 1 161 ? -10.751 -8.903  -4.363  1   84.66  ? 157 ARG A NE  1 
ATOM   1270 C  CZ  . ARG A 1 161 ? -10.889 -8.538  -3.095  1   82.69  ? 157 ARG A CZ  1 
ATOM   1271 N  NH1 . ARG A 1 161 ? -9.848  -8.555  -2.284  1   81.69  ? 157 ARG A NH1 1 
ATOM   1272 N  NH2 . ARG A 1 161 ? -12.07  -8.158  -2.646  1   67.62  ? 157 ARG A NH2 1 
ATOM   1273 N  N   . THR A 1 162 ? -8.178  -12.524 -5.996  1   53.38  ? 158 THR A N   1 
ATOM   1274 C  CA  . THR A 1 162 ? -6.844  -12.804 -5.468  1   57.72  ? 158 THR A CA  1 
ATOM   1275 C  C   . THR A 1 162 ? -6.779  -12.386 -3.996  1   52.54  ? 158 THR A C   1 
ATOM   1276 O  O   . THR A 1 162 ? -7.111  -11.253 -3.674  1   48.39  ? 158 THR A O   1 
ATOM   1277 C  CB  . THR A 1 162 ? -5.779  -12.063 -6.282  1   63.52  ? 158 THR A CB  1 
ATOM   1278 O  OG1 . THR A 1 162 ? -5.867  -12.488 -7.639  1   72.6   ? 158 THR A OG1 1 
ATOM   1279 C  CG2 . THR A 1 162 ? -4.37   -12.331 -5.778  1   57.24  ? 158 THR A CG2 1 
ATOM   1280 N  N   . TYR A 1 163 ? -6.351  -13.303 -3.115  1   48.36  ? 159 TYR A N   1 
ATOM   1281 C  CA  . TYR A 1 163 ? -6.145  -13.001 -1.702  1   48.23  ? 159 TYR A CA  1 
ATOM   1282 C  C   . TYR A 1 163 ? -4.66   -13.136 -1.332  1   47.11  ? 159 TYR A C   1 
ATOM   1283 O  O   . TYR A 1 163 ? -3.785  -13.27  -2.182  1   44.38  ? 159 TYR A O   1 
ATOM   1284 C  CB  . TYR A 1 163 ? -7.067  -13.827 -0.794  1   46.53  ? 159 TYR A CB  1 
ATOM   1285 C  CG  . TYR A 1 163 ? -8.551  -13.805 -1.151  1   48.83  ? 159 TYR A CG  1 
ATOM   1286 C  CD1 . TYR A 1 163 ? -9.252  -12.613 -1.338  1   45.51  ? 159 TYR A CD1 1 
ATOM   1287 C  CD2 . TYR A 1 163 ? -9.237  -14.997 -1.366  1   46.85  ? 159 TYR A CD2 1 
ATOM   1288 C  CE1 . TYR A 1 163 ? -10.587 -12.612 -1.69   1   44.69  ? 159 TYR A CE1 1 
ATOM   1289 C  CE2 . TYR A 1 163 ? -10.571 -15.012 -1.734  1   44.84  ? 159 TYR A CE2 1 
ATOM   1290 C  CZ  . TYR A 1 163 ? -11.242 -13.816 -1.903  1   49.8   ? 159 TYR A CZ  1 
ATOM   1291 O  OH  . TYR A 1 163 ? -12.559 -13.867 -2.269  1   54.71  ? 159 TYR A OH  1 
HETATM 1292 N  N   . TPO A 1 164 ? -4.391  -13.036 -0.035  1   48.45  ? 160 TPO A N   1 
HETATM 1293 C  CA  . TPO A 1 164 ? -2.997  -13.089 0.467   1   53.57  ? 160 TPO A CA  1 
HETATM 1294 C  CB  . TPO A 1 164 ? -2.972  -12.815 1.977   1   50.23  ? 160 TPO A CB  1 
HETATM 1295 C  CG2 . TPO A 1 164 ? -1.58   -12.58  2.512   1   42.69  ? 160 TPO A CG2 1 
HETATM 1296 O  OG1 . TPO A 1 164 ? -3.751  -11.598 2.212   1   51.67  ? 160 TPO A OG1 1 
HETATM 1297 P  P   . TPO A 1 164 ? -5.149  -11.636 2.997   1   50.47  ? 160 TPO A P   1 
HETATM 1298 O  O1P . TPO A 1 164 ? -6.074  -12.455 2.142   1   47.5   ? 160 TPO A O1P 1 
HETATM 1299 O  O2P . TPO A 1 164 ? -5.58   -10.204 3.125   1   44.27  ? 160 TPO A O2P 1 
HETATM 1300 O  O3P . TPO A 1 164 ? -4.862  -12.281 4.324   1   47.27  ? 160 TPO A O3P 1 
HETATM 1301 C  C   . TPO A 1 164 ? -2.352  -14.424 0.102   1   52.37  ? 160 TPO A C   1 
HETATM 1302 O  O   . TPO A 1 164 ? -3.019  -15.453 0.218   1   51.81  ? 160 TPO A O   1 
ATOM   1303 N  N   . HIS A 1 165 ? -1.084  -14.385 -0.293  1   54.82  ? 161 HIS A N   1 
ATOM   1304 C  CA  . HIS A 1 165 ? -0.357  -15.609 -0.7    1   56.52  ? 161 HIS A CA  1 
ATOM   1305 C  C   . HIS A 1 165 ? 0.416   -16.156 0.494   1   59.99  ? 161 HIS A C   1 
ATOM   1306 O  O   . HIS A 1 165 ? 0.493   -15.484 1.536   1   69.41  ? 161 HIS A O   1 
ATOM   1307 C  CB  . HIS A 1 165 ? 0.56    -15.271 -1.878  1   58.22  ? 161 HIS A CB  1 
ATOM   1308 C  CG  . HIS A 1 165 ? 1.567   -16.302 -2.252  1   85.27  ? 161 HIS A CG  1 
ATOM   1309 N  ND1 . HIS A 1 165 ? 1.246   -17.589 -2.623  1   81.56  ? 161 HIS A ND1 1 
ATOM   1310 C  CD2 . HIS A 1 165 ? 2.899   -16.226 -2.298  1   99.52  ? 161 HIS A CD2 1 
ATOM   1311 C  CE1 . HIS A 1 165 ? 2.359   -18.256 -2.878  1   80.43  ? 161 HIS A CE1 1 
ATOM   1312 N  NE2 . HIS A 1 165 ? 3.374   -17.447 -2.691  1   100.25 ? 161 HIS A NE2 1 
ATOM   1313 N  N   . GLU A 1 166 ? 0.954   -17.362 0.35    1   77.11  ? 162 GLU A N   1 
ATOM   1314 C  CA  . GLU A 1 166 ? 1.783   -17.976 1.419   1   106.91 ? 162 GLU A CA  1 
ATOM   1315 C  C   . GLU A 1 166 ? 0.925   -18.057 2.684   1   109.41 ? 162 GLU A C   1 
ATOM   1316 O  O   . GLU A 1 166 ? 1.48    -17.93  3.791   1   130.35 ? 162 GLU A O   1 
ATOM   1317 C  CB  . GLU A 1 166 ? 3.105   -17.229 1.609   1   112.07 ? 162 GLU A CB  1 
ATOM   1318 C  CG  . GLU A 1 166 ? 4.241   -17.792 0.762   1   116.75 ? 162 GLU A CG  1 
ATOM   1319 C  CD  . GLU A 1 166 ? 5.174   -16.722 0.229   1   117.34 ? 162 GLU A CD  1 
ATOM   1320 O  OE1 . GLU A 1 166 ? 5.793   -16.947 -0.829  1   133.02 ? 162 GLU A OE1 1 
ATOM   1321 O  OE2 . GLU A 1 166 ? 5.275   -15.658 0.872   1   107.18 ? 162 GLU A OE2 1 
ATOM   1322 N  N   . VAL A 1 167 ? -0.378  -18.255 2.51    1   81.37  ? 163 VAL A N   1 
ATOM   1323 C  CA  . VAL A 1 167 ? -1.264  -18.468 3.679   1   62.2   ? 163 VAL A CA  1 
ATOM   1324 C  C   . VAL A 1 167 ? -1.141  -19.951 4.031   1   53.87  ? 163 VAL A C   1 
ATOM   1325 O  O   . VAL A 1 167 ? -0.628  -20.693 3.179   1   54.33  ? 163 VAL A O   1 
ATOM   1326 C  CB  . VAL A 1 167 ? -2.704  -18.075 3.31    1   56.92  ? 163 VAL A CB  1 
ATOM   1327 C  CG1 . VAL A 1 167 ? -2.893  -16.566 3.324   1   54.23  ? 163 VAL A CG1 1 
ATOM   1328 C  CG2 . VAL A 1 167 ? -3.114  -18.65  1.962   1   49.55  ? 163 VAL A CG2 1 
ATOM   1329 N  N   . VAL A 1 168 ? -1.556  -20.343 5.231   1   43.22  ? 164 VAL A N   1 
ATOM   1330 C  CA  . VAL A 1 168 ? -1.535  -21.769 5.686   1   43.21  ? 164 VAL A CA  1 
ATOM   1331 C  C   . VAL A 1 168 ? -0.124  -22.18  6.128   1   48.05  ? 164 VAL A C   1 
ATOM   1332 O  O   . VAL A 1 168 ? 0.804   -22.084 5.315   1   51.97  ? 164 VAL A O   1 
ATOM   1333 C  CB  . VAL A 1 168 ? -2.128  -22.831 4.729   1   41.39  ? 164 VAL A CB  1 
ATOM   1334 C  CG1 . VAL A 1 168 ? -2.376  -24.145 5.453   1   40.81  ? 164 VAL A CG1 1 
ATOM   1335 C  CG2 . VAL A 1 168 ? -3.409  -22.361 4.051   1   39.51  ? 164 VAL A CG2 1 
ATOM   1336 N  N   . THR A 1 169 ? 0.022   -22.585 7.388   1   45.25  ? 165 THR A N   1 
ATOM   1337 C  CA  . THR A 1 169 ? 1.28    -23.163 7.852   1   46.2   ? 165 THR A CA  1 
ATOM   1338 C  C   . THR A 1 169 ? 1.793   -24.171 6.814   1   50.03  ? 165 THR A C   1 
ATOM   1339 O  O   . THR A 1 169 ? 1.05    -25.049 6.377   1   42.09  ? 165 THR A O   1 
ATOM   1340 C  CB  . THR A 1 169 ? 1.085   -23.856 9.203   1   46.01  ? 165 THR A CB  1 
ATOM   1341 O  OG1 . THR A 1 169 ? 0.676   -22.853 10.12   1   42.33  ? 165 THR A OG1 1 
ATOM   1342 C  CG2 . THR A 1 169 ? 2.351   -24.512 9.722   1   43.9   ? 165 THR A CG2 1 
ATOM   1343 N  N   . LEU A 1 170 ? 3.093   -24.081 6.495   1   48.42  ? 166 LEU A N   1 
ATOM   1344 C  CA  . LEU A 1 170 ? 3.697   -24.701 5.33    1   47     ? 166 LEU A CA  1 
ATOM   1345 C  C   . LEU A 1 170 ? 3.323   -26.173 5.186   1   48.99  ? 166 LEU A C   1 
ATOM   1346 O  O   . LEU A 1 170 ? 3.047   -26.612 4.08    1   48.49  ? 166 LEU A O   1 
ATOM   1347 C  CB  . LEU A 1 170 ? 5.211   -24.543 5.413   1   51.3   ? 166 LEU A CB  1 
ATOM   1348 C  CG  . LEU A 1 170 ? 5.989   -25.114 4.222   1   50.64  ? 166 LEU A CG  1 
ATOM   1349 C  CD1 . LEU A 1 170 ? 5.69    -24.283 2.969   1   51.35  ? 166 LEU A CD1 1 
ATOM   1350 C  CD2 . LEU A 1 170 ? 7.472   -25.151 4.538   1   43.94  ? 166 LEU A CD2 1 
ATOM   1351 N  N   . TRP A 1 171 ? 3.409   -26.959 6.27    1   48.34  ? 167 TRP A N   1 
ATOM   1352 C  CA  . TRP A 1 171 ? 3.205   -28.393 6.118   1   46.39  ? 167 TRP A CA  1 
ATOM   1353 C  C   . TRP A 1 171 ? 1.774   -28.705 5.654   1   46.23  ? 167 TRP A C   1 
ATOM   1354 O  O   . TRP A 1 171 ? 1.505   -29.831 5.237   1   46.23  ? 167 TRP A O   1 
ATOM   1355 C  CB  . TRP A 1 171 ? 3.477   -29.134 7.432   1   42.86  ? 167 TRP A CB  1 
ATOM   1356 C  CG  . TRP A 1 171 ? 4.883   -29.115 7.954   1   43.6   ? 167 TRP A CG  1 
ATOM   1357 C  CD1 . TRP A 1 171 ? 6.026   -28.667 7.35    1   44.47  ? 167 TRP A CD1 1 
ATOM   1358 C  CD2 . TRP A 1 171 ? 5.281   -29.636 9.241   1   42.76  ? 167 TRP A CD2 1 
ATOM   1359 N  NE1 . TRP A 1 171 ? 7.097   -28.825 8.196   1   44.24  ? 167 TRP A NE1 1 
ATOM   1360 C  CE2 . TRP A 1 171 ? 6.678   -29.428 9.354   1   43.67  ? 167 TRP A CE2 1 
ATOM   1361 C  CE3 . TRP A 1 171 ? 4.591   -30.236 10.305  1   43.46  ? 167 TRP A CE3 1 
ATOM   1362 C  CZ2 . TRP A 1 171 ? 7.398   -29.815 10.484  1   44.73  ? 167 TRP A CZ2 1 
ATOM   1363 C  CZ3 . TRP A 1 171 ? 5.304   -30.632 11.421  1   45.35  ? 167 TRP A CZ3 1 
ATOM   1364 C  CH2 . TRP A 1 171 ? 6.693   -30.426 11.504  1   44.61  ? 167 TRP A CH2 1 
ATOM   1365 N  N   . TYR A 1 172 ? 0.849   -27.734 5.777   1   39.18  ? 168 TYR A N   1 
ATOM   1366 C  CA  . TYR A 1 172 ? -0.575  -27.964 5.559   1   41.42  ? 168 TYR A CA  1 
ATOM   1367 C  C   . TYR A 1 172 ? -1.055  -27.238 4.295   1   44.48  ? 168 TYR A C   1 
ATOM   1368 O  O   . TYR A 1 172 ? -2.247  -27.249 3.978   1   44.66  ? 168 TYR A O   1 
ATOM   1369 C  CB  . TYR A 1 172 ? -1.372  -27.663 6.837   1   34.88  ? 168 TYR A CB  1 
ATOM   1370 C  CG  . TYR A 1 172 ? -0.888  -28.51  8.003   1   38.65  ? 168 TYR A CG  1 
ATOM   1371 C  CD1 . TYR A 1 172 ? -1.308  -29.828 8.171   1   40.91  ? 168 TYR A CD1 1 
ATOM   1372 C  CD2 . TYR A 1 172 ? 0.04    -28.015 8.912   1   39.91  ? 168 TYR A CD2 1 
ATOM   1373 C  CE1 . TYR A 1 172 ? -0.838  -30.619 9.218   1   38.96  ? 168 TYR A CE1 1 
ATOM   1374 C  CE2 . TYR A 1 172 ? 0.509   -28.793 9.96    1   41.7   ? 168 TYR A CE2 1 
ATOM   1375 C  CZ  . TYR A 1 172 ? 0.074   -30.099 10.122  1   40.34  ? 168 TYR A CZ  1 
ATOM   1376 O  OH  . TYR A 1 172 ? 0.571   -30.817 11.186  1   39.57  ? 168 TYR A OH  1 
ATOM   1377 N  N   . ARG A 1 173 ? -0.095  -26.653 3.56    1   42.32  ? 169 ARG A N   1 
ATOM   1378 C  CA  . ARG A 1 173 ? -0.375  -25.722 2.479   1   41.88  ? 169 ARG A CA  1 
ATOM   1379 C  C   . ARG A 1 173 ? -0.521  -26.49  1.168   1   42.58  ? 169 ARG A C   1 
ATOM   1380 O  O   . ARG A 1 173 ? 0.303   -27.35  0.838   1   41.86  ? 169 ARG A O   1 
ATOM   1381 C  CB  . ARG A 1 173 ? 0.731   -24.663 2.406   1   37.06  ? 169 ARG A CB  1 
ATOM   1382 C  CG  . ARG A 1 173 ? 0.493   -23.594 1.35    1   38.01  ? 169 ARG A CG  1 
ATOM   1383 C  CD  . ARG A 1 173 ? 1.658   -22.623 1.256   1   39.43  ? 169 ARG A CD  1 
ATOM   1384 N  NE  . ARG A 1 173 ? 1.965   -22.122 2.602   1   43.06  ? 169 ARG A NE  1 
ATOM   1385 C  CZ  . ARG A 1 173 ? 3.048   -21.444 2.956   1   45     ? 169 ARG A CZ  1 
ATOM   1386 N  NH1 . ARG A 1 173 ? 3.986   -21.143 2.08    1   44.6   ? 169 ARG A NH1 1 
ATOM   1387 N  NH2 . ARG A 1 173 ? 3.197   -21.092 4.212   1   47.09  ? 169 ARG A NH2 1 
ATOM   1388 N  N   . ALA A 1 174 ? -1.567  -26.115 0.422   1   39.23  ? 170 ALA A N   1 
ATOM   1389 C  CA  . ALA A 1 174 ? -1.983  -26.774 -0.804  1   38.06  ? 170 ALA A CA  1 
ATOM   1390 C  C   . ALA A 1 174 ? -1.028  -26.474 -1.957  1   40.03  ? 170 ALA A C   1 
ATOM   1391 O  O   . ALA A 1 174 ? -0.445  -25.396 -2.065  1   43.61  ? 170 ALA A O   1 
ATOM   1392 C  CB  . ALA A 1 174 ? -3.396  -26.331 -1.122  1   34.76  ? 170 ALA A CB  1 
ATOM   1393 N  N   . PRO A 1 175 ? -0.893  -27.395 -2.924  1   42.95  ? 171 PRO A N   1 
ATOM   1394 C  CA  . PRO A 1 175 ? 0       -27.155 -4.059  1   41.94  ? 171 PRO A CA  1 
ATOM   1395 C  C   . PRO A 1 175 ? -0.319  -25.847 -4.793  1   43.04  ? 171 PRO A C   1 
ATOM   1396 O  O   . PRO A 1 175 ? 0.599   -25.16  -5.256  1   43.72  ? 171 PRO A O   1 
ATOM   1397 C  CB  . PRO A 1 175 ? -0.148  -28.399 -4.944  1   37.25  ? 171 PRO A CB  1 
ATOM   1398 C  CG  . PRO A 1 175 ? -1.448  -29.001 -4.489  1   42.33  ? 171 PRO A CG  1 
ATOM   1399 C  CD  . PRO A 1 175 ? -1.614  -28.668 -2.997  1   38.68  ? 171 PRO A CD  1 
ATOM   1400 N  N   . GLU A 1 176 ? -1.613  -25.506 -4.891  1   40.85  ? 172 GLU A N   1 
ATOM   1401 C  CA  . GLU A 1 176 ? -2.022  -24.367 -5.696  1   42.91  ? 172 GLU A CA  1 
ATOM   1402 C  C   . GLU A 1 176 ? -1.496  -23.071 -5.076  1   44.83  ? 172 GLU A C   1 
ATOM   1403 O  O   . GLU A 1 176 ? -1.305  -22.091 -5.794  1   48.19  ? 172 GLU A O   1 
ATOM   1404 C  CB  . GLU A 1 176 ? -3.508  -24.342 -6.065  1   43.68  ? 172 GLU A CB  1 
ATOM   1405 C  CG  . GLU A 1 176 ? -4.516  -24.305 -4.921  1   42.8   ? 172 GLU A CG  1 
ATOM   1406 C  CD  . GLU A 1 176 ? -4.932  -25.664 -4.359  1   46.29  ? 172 GLU A CD  1 
ATOM   1407 O  OE1 . GLU A 1 176 ? -6.067  -25.786 -3.818  1   46.2   ? 172 GLU A OE1 1 
ATOM   1408 O  OE2 . GLU A 1 176 ? -4.112  -26.597 -4.456  1   40.44  ? 172 GLU A OE2 1 
ATOM   1409 N  N   . ILE A 1 177 ? -1.233  -23.078 -3.759  1   38.17  ? 173 ILE A N   1 
ATOM   1410 C  CA  . ILE A 1 177 ? -0.648  -21.909 -3.123  1   39.33  ? 173 ILE A CA  1 
ATOM   1411 C  C   . ILE A 1 177 ? 0.86    -21.92  -3.387  1   42.68  ? 173 ILE A C   1 
ATOM   1412 O  O   . ILE A 1 177 ? 1.449   -20.913 -3.766  1   44.91  ? 173 ILE A O   1 
ATOM   1413 C  CB  . ILE A 1 177 ? -1.034  -21.859 -1.629  1   41.2   ? 173 ILE A CB  1 
ATOM   1414 C  CG1 . ILE A 1 177 ? -2.552  -21.781 -1.454  1   41     ? 173 ILE A CG1 1 
ATOM   1415 C  CG2 . ILE A 1 177 ? -0.372  -20.692 -0.906  1   40.38  ? 173 ILE A CG2 1 
ATOM   1416 C  CD1 . ILE A 1 177 ? -3.036  -22.02  -0.037  1   38.99  ? 173 ILE A CD1 1 
ATOM   1417 N  N   . LEU A 1 178 ? 1.475   -23.087 -3.205  1   43.41  ? 174 LEU A N   1 
ATOM   1418 C  CA  . LEU A 1 178 ? 2.893   -23.292 -3.426  1   42.97  ? 174 LEU A CA  1 
ATOM   1419 C  C   . LEU A 1 178 ? 3.276   -22.96  -4.865  1   47.25  ? 174 LEU A C   1 
ATOM   1420 O  O   . LEU A 1 178 ? 4.404   -22.525 -5.101  1   52.91  ? 174 LEU A O   1 
ATOM   1421 C  CB  . LEU A 1 178 ? 3.279   -24.728 -3.073  1   44.02  ? 174 LEU A CB  1 
ATOM   1422 C  CG  . LEU A 1 178 ? 3.245   -25.075 -1.581  1   38.97  ? 174 LEU A CG  1 
ATOM   1423 C  CD1 . LEU A 1 178 ? 3.286   -26.587 -1.413  1   36.11  ? 174 LEU A CD1 1 
ATOM   1424 C  CD2 . LEU A 1 178 ? 4.452   -24.417 -0.948  1   37.3   ? 174 LEU A CD2 1 
ATOM   1425 N  N   . LEU A 1 179 ? 2.36    -23.151 -5.824  1   44.27  ? 175 LEU A N   1 
ATOM   1426 C  CA  . LEU A 1 179 ? 2.689   -22.829 -7.21   1   45.35  ? 175 LEU A CA  1 
ATOM   1427 C  C   . LEU A 1 179 ? 2.29    -21.395 -7.577  1   49.49  ? 175 LEU A C   1 
ATOM   1428 O  O   . LEU A 1 179 ? 2.328   -21.027 -8.748  1   49.43  ? 175 LEU A O   1 
ATOM   1429 C  CB  . LEU A 1 179 ? 2.068   -23.846 -8.157  1   41.12  ? 175 LEU A CB  1 
ATOM   1430 C  CG  . LEU A 1 179 ? 2.652   -25.255 -8.066  1   45.34  ? 175 LEU A CG  1 
ATOM   1431 C  CD1 . LEU A 1 179 ? 1.838   -26.238 -8.875  1   45.88  ? 175 LEU A CD1 1 
ATOM   1432 C  CD2 . LEU A 1 179 ? 4.119   -25.245 -8.501  1   42.55  ? 175 LEU A CD2 1 
ATOM   1433 N  N   . GLY A 1 180 ? 1.893   -20.579 -6.589  1   47.74  ? 176 GLY A N   1 
ATOM   1434 C  CA  . GLY A 1 180 ? 1.755   -19.149 -6.819  1   45.76  ? 176 GLY A CA  1 
ATOM   1435 C  C   . GLY A 1 180 ? 0.514   -18.781 -7.627  1   49.65  ? 176 GLY A C   1 
ATOM   1436 O  O   . GLY A 1 180 ? 0.496   -17.723 -8.251  1   53.08  ? 176 GLY A O   1 
ATOM   1437 N  N   . CYS A 1 181 ? -0.512  -19.646 -7.598  1   47.39  ? 177 CYS A N   1 
ATOM   1438 C  CA  . CYS A 1 181 ? -1.721  -19.472 -8.399  1   51.36  ? 177 CYS A CA  1 
ATOM   1439 C  C   . CYS A 1 181 ? -2.388  -18.138 -8.061  1   51.4   ? 177 CYS A C   1 
ATOM   1440 O  O   . CYS A 1 181 ? -2.331  -17.678 -6.916  1   50.17  ? 177 CYS A O   1 
ATOM   1441 C  CB  . CYS A 1 181 ? -2.642  -20.687 -8.282  1   55.98  ? 177 CYS A CB  1 
ATOM   1442 S  SG  . CYS A 1 181 ? -2.145  -22.085 -9.342  1   69.51  ? 177 CYS A SG  1 
ATOM   1443 N  N   . LYS A 1 182 ? -2.98   -17.502 -9.082  1   45.08  ? 178 LYS A N   1 
ATOM   1444 C  CA  . LYS A 1 182 ? -3.655  -16.229 -8.88   1   47.6   ? 178 LYS A CA  1 
ATOM   1445 C  C   . LYS A 1 182 ? -4.827  -16.388 -7.902  1   46.97  ? 178 LYS A C   1 
ATOM   1446 O  O   . LYS A 1 182 ? -5.081  -15.507 -7.079  1   46.42  ? 178 LYS A O   1 
ATOM   1447 C  CB  . LYS A 1 182 ? -4.077  -15.72  -10.261 1   54.28  ? 178 LYS A CB  1 
ATOM   1448 C  CG  . LYS A 1 182 ? -4.865  -14.423 -10.32  1   71.91  ? 178 LYS A CG  1 
ATOM   1449 C  CD  . LYS A 1 182 ? -5.2    -13.928 -11.733 1   79.05  ? 178 LYS A CD  1 
ATOM   1450 C  CE  . LYS A 1 182 ? -5.324  -12.411 -11.744 1   88.98  ? 178 LYS A CE  1 
ATOM   1451 N  NZ  . LYS A 1 182 ? -6.332  -11.863 -12.657 1   86.13  ? 178 LYS A NZ  1 
ATOM   1452 N  N   . TYR A 1 183 ? -5.552  -17.514 -8.01   1   44.57  ? 179 TYR A N   1 
ATOM   1453 C  CA  . TYR A 1 183 ? -6.775  -17.723 -7.252  1   45.63  ? 179 TYR A CA  1 
ATOM   1454 C  C   . TYR A 1 183 ? -6.687  -19.026 -6.482  1   44.96  ? 179 TYR A C   1 
ATOM   1455 O  O   . TYR A 1 183 ? -6.201  -20.032 -7.005  1   40.77  ? 179 TYR A O   1 
ATOM   1456 C  CB  . TYR A 1 183 ? -7.985  -17.926 -8.17   1   47.31  ? 179 TYR A CB  1 
ATOM   1457 C  CG  . TYR A 1 183 ? -8.285  -16.716 -9.037  1   48.15  ? 179 TYR A CG  1 
ATOM   1458 C  CD1 . TYR A 1 183 ? -8.484  -15.464 -8.461  1   47.34  ? 179 TYR A CD1 1 
ATOM   1459 C  CD2 . TYR A 1 183 ? -8.332  -16.825 -10.418 1   44.96  ? 179 TYR A CD2 1 
ATOM   1460 C  CE1 . TYR A 1 183 ? -8.756  -14.355 -9.248  1   51.95  ? 179 TYR A CE1 1 
ATOM   1461 C  CE2 . TYR A 1 183 ? -8.609  -15.728 -11.214 1   45.99  ? 179 TYR A CE2 1 
ATOM   1462 C  CZ  . TYR A 1 183 ? -8.808  -14.494 -10.624 1   52.61  ? 179 TYR A CZ  1 
ATOM   1463 O  OH  . TYR A 1 183 ? -9.071  -13.41  -11.392 1   59.03  ? 179 TYR A OH  1 
ATOM   1464 N  N   . TYR A 1 184 ? -7.178  -18.966 -5.241  1   43.5   ? 180 TYR A N   1 
ATOM   1465 C  CA  . TYR A 1 184 ? -7.41   -20.17  -4.473  1   44.22  ? 180 TYR A CA  1 
ATOM   1466 C  C   . TYR A 1 184 ? -8.766  -20.051 -3.773  1   46.06  ? 180 TYR A C   1 
ATOM   1467 O  O   . TYR A 1 184 ? -9.281  -18.946 -3.586  1   43.28  ? 180 TYR A O   1 
ATOM   1468 C  CB  . TYR A 1 184 ? -6.222  -20.489 -3.564  1   40.21  ? 180 TYR A CB  1 
ATOM   1469 C  CG  . TYR A 1 184 ? -6.051  -19.467 -2.451  1   41.92  ? 180 TYR A CG  1 
ATOM   1470 C  CD1 . TYR A 1 184 ? -6.851  -19.46  -1.303  1   37.8   ? 180 TYR A CD1 1 
ATOM   1471 C  CD2 . TYR A 1 184 ? -5.062  -18.508 -2.57   1   43.09  ? 180 TYR A CD2 1 
ATOM   1472 C  CE1 . TYR A 1 184 ? -6.644  -18.52  -0.309  1   41.49  ? 180 TYR A CE1 1 
ATOM   1473 C  CE2 . TYR A 1 184 ? -4.85   -17.564 -1.582  1   47.27  ? 180 TYR A CE2 1 
ATOM   1474 C  CZ  . TYR A 1 184 ? -5.642  -17.569 -0.453  1   46.19  ? 180 TYR A CZ  1 
ATOM   1475 O  OH  . TYR A 1 184 ? -5.388  -16.572 0.441   1   47.97  ? 180 TYR A OH  1 
ATOM   1476 N  N   . SER A 1 185 ? -9.309  -21.215 -3.381  1   41.05  ? 181 SER A N   1 
ATOM   1477 C  CA  . SER A 1 185 ? -10.686 -21.307 -2.948  1   44.94  ? 181 SER A CA  1 
ATOM   1478 C  C   . SER A 1 185 ? -10.789 -22.284 -1.785  1   44.24  ? 181 SER A C   1 
ATOM   1479 O  O   . SER A 1 185 ? -9.804  -22.571 -1.107  1   43.08  ? 181 SER A O   1 
ATOM   1480 C  CB  . SER A 1 185 ? -11.604 -21.728 -4.094  1   45.2   ? 181 SER A CB  1 
ATOM   1481 O  OG  . SER A 1 185 ? -12.967 -21.474 -3.771  1   44.85  ? 181 SER A OG  1 
ATOM   1482 N  N   . THR A 1 186 ? -12.005 -22.81  -1.608  1   42.4   ? 182 THR A N   1 
ATOM   1483 C  CA  . THR A 1 186 ? -12.365 -23.652 -0.485  1   42.79  ? 182 THR A CA  1 
ATOM   1484 C  C   . THR A 1 186 ? -11.488 -24.898 -0.433  1   40.18  ? 182 THR A C   1 
ATOM   1485 O  O   . THR A 1 186 ? -11.309 -25.451 0.634   1   40.5   ? 182 THR A O   1 
ATOM   1486 C  CB  . THR A 1 186 ? -13.853 -23.975 -0.596  1   44.36  ? 182 THR A CB  1 
ATOM   1487 O  OG1 . THR A 1 186 ? -14.07  -24.432 -1.932  1   43.17  ? 182 THR A OG1 1 
ATOM   1488 C  CG2 . THR A 1 186 ? -14.713 -22.76  -0.29   1   38.22  ? 182 THR A CG2 1 
ATOM   1489 N  N   . ALA A 1 187 ? -10.933 -25.313 -1.576  1   41.3   ? 183 ALA A N   1 
ATOM   1490 C  CA  . ALA A 1 187 ? -10.128 -26.518 -1.704  1   38.93  ? 183 ALA A CA  1 
ATOM   1491 C  C   . ALA A 1 187 ? -8.861  -26.456 -0.844  1   41.93  ? 183 ALA A C   1 
ATOM   1492 O  O   . ALA A 1 187 ? -8.347  -27.502 -0.454  1   42.19  ? 183 ALA A O   1 
ATOM   1493 C  CB  . ALA A 1 187 ? -9.804  -26.769 -3.158  1   35.8   ? 183 ALA A CB  1 
ATOM   1494 N  N   . VAL A 1 188 ? -8.348  -25.251 -0.552  1   40.25  ? 184 VAL A N   1 
ATOM   1495 C  CA  . VAL A 1 188 ? -7.144  -25.142 0.265   1   41.13  ? 184 VAL A CA  1 
ATOM   1496 C  C   . VAL A 1 188 ? -7.406  -25.664 1.69    1   42.69  ? 184 VAL A C   1 
ATOM   1497 O  O   . VAL A 1 188 ? -6.503  -26.242 2.31    1   45.55  ? 184 VAL A O   1 
ATOM   1498 C  CB  . VAL A 1 188 ? -6.492  -23.744 0.301   1   40.89  ? 184 VAL A CB  1 
ATOM   1499 C  CG1 . VAL A 1 188 ? -6.388  -23.097 -1.072  1   35.81  ? 184 VAL A CG1 1 
ATOM   1500 C  CG2 . VAL A 1 188 ? -7.174  -22.816 1.306   1   39.97  ? 184 VAL A CG2 1 
ATOM   1501 N  N   . ASP A 1 189 ? -8.631  -25.455 2.217   1   40.22  ? 185 ASP A N   1 
ATOM   1502 C  CA  . ASP A 1 189 ? -8.993  -25.953 3.535   1   38.55  ? 185 ASP A CA  1 
ATOM   1503 C  C   . ASP A 1 189 ? -9.125  -27.471 3.484   1   40.59  ? 185 ASP A C   1 
ATOM   1504 O  O   . ASP A 1 189 ? -8.755  -28.138 4.436   1   42.5   ? 185 ASP A O   1 
ATOM   1505 C  CB  . ASP A 1 189 ? -10.2   -25.26  4.147   1   39.75  ? 185 ASP A CB  1 
ATOM   1506 C  CG  . ASP A 1 189 ? -9.993  -23.811 4.57    1   44.07  ? 185 ASP A CG  1 
ATOM   1507 O  OD1 . ASP A 1 189 ? -8.821  -23.41  4.738   1   46.79  ? 185 ASP A OD1 1 
ATOM   1508 O  OD2 . ASP A 1 189 ? -11.005 -23.067 4.686   1   45.33  ? 185 ASP A OD2 1 
ATOM   1509 N  N   . ILE A 1 190 ? -9.611  -28.029 2.371   1   40.15  ? 186 ILE A N   1 
ATOM   1510 C  CA  . ILE A 1 190 ? -9.747  -29.479 2.309   1   43.94  ? 186 ILE A CA  1 
ATOM   1511 C  C   . ILE A 1 190 ? -8.37   -30.158 2.323   1   45.63  ? 186 ILE A C   1 
ATOM   1512 O  O   . ILE A 1 190 ? -8.165  -31.187 2.983   1   40.66  ? 186 ILE A O   1 
ATOM   1513 C  CB  . ILE A 1 190 ? -10.632 -29.916 1.128   1   42.3   ? 186 ILE A CB  1 
ATOM   1514 C  CG1 . ILE A 1 190 ? -12.102 -29.55  1.4     1   41.36  ? 186 ILE A CG1 1 
ATOM   1515 C  CG2 . ILE A 1 190 ? -10.47  -31.412 0.825   1   37.66  ? 186 ILE A CG2 1 
ATOM   1516 C  CD1 . ILE A 1 190 ? -12.762 -30.372 2.5     1   44.55  ? 186 ILE A CD1 1 
ATOM   1517 N  N   . TRP A 1 191 ? -7.423  -29.572 1.588   1   43.87  ? 187 TRP A N   1 
ATOM   1518 C  CA  . TRP A 1 191 ? -6.069  -30.092 1.563   1   45.95  ? 187 TRP A CA  1 
ATOM   1519 C  C   . TRP A 1 191 ? -5.548  -30.199 2.999   1   43.86  ? 187 TRP A C   1 
ATOM   1520 O  O   . TRP A 1 191 ? -5.098  -31.253 3.442   1   46.97  ? 187 TRP A O   1 
ATOM   1521 C  CB  . TRP A 1 191 ? -5.167  -29.222 0.672   1   43.23  ? 187 TRP A CB  1 
ATOM   1522 C  CG  . TRP A 1 191 ? -3.76   -29.741 0.573   1   43.87  ? 187 TRP A CG  1 
ATOM   1523 C  CD1 . TRP A 1 191 ? -2.744  -29.501 1.449   1   42.66  ? 187 TRP A CD1 1 
ATOM   1524 C  CD2 . TRP A 1 191 ? -3.217  -30.593 -0.459  1   43.42  ? 187 TRP A CD2 1 
ATOM   1525 N  NE1 . TRP A 1 191 ? -1.606  -30.141 1.033   1   46.92  ? 187 TRP A NE1 1 
ATOM   1526 C  CE2 . TRP A 1 191 ? -1.861  -30.809 -0.137  1   42.68  ? 187 TRP A CE2 1 
ATOM   1527 C  CE3 . TRP A 1 191 ? -3.734  -31.182 -1.619  1   43.71  ? 187 TRP A CE3 1 
ATOM   1528 C  CZ2 . TRP A 1 191 ? -1.025  -31.594 -0.927  1   41.42  ? 187 TRP A CZ2 1 
ATOM   1529 C  CZ3 . TRP A 1 191 ? -2.899  -31.954 -2.402  1   40.47  ? 187 TRP A CZ3 1 
ATOM   1530 C  CH2 . TRP A 1 191 ? -1.562  -32.154 -2.064  1   37.63  ? 187 TRP A CH2 1 
ATOM   1531 N  N   . SER A 1 192 ? -5.632  -29.1   3.741   1   39.1   ? 188 SER A N   1 
ATOM   1532 C  CA  . SER A 1 192 ? -5.203  -29.108 5.13    1   40.18  ? 188 SER A CA  1 
ATOM   1533 C  C   . SER A 1 192 ? -5.819  -30.275 5.922   1   40.38  ? 188 SER A C   1 
ATOM   1534 O  O   . SER A 1 192 ? -5.108  -31.023 6.587   1   41.87  ? 188 SER A O   1 
ATOM   1535 C  CB  . SER A 1 192 ? -5.475  -27.765 5.766   1   39.38  ? 188 SER A CB  1 
ATOM   1536 O  OG  . SER A 1 192 ? -4.731  -26.758 5.095   1   38.74  ? 188 SER A OG  1 
ATOM   1537 N  N   . LEU A 1 193 ? -7.146  -30.448 5.843   1   39.54  ? 189 LEU A N   1 
ATOM   1538 C  CA  . LEU A 1 193 ? -7.843  -31.55  6.485   1   38.38  ? 189 LEU A CA  1 
ATOM   1539 C  C   . LEU A 1 193 ? -7.357  -32.911 5.997   1   41.21  ? 189 LEU A C   1 
ATOM   1540 O  O   . LEU A 1 193 ? -7.382  -33.857 6.774   1   43.6   ? 189 LEU A O   1 
ATOM   1541 C  CB  . LEU A 1 193 ? -9.339  -31.435 6.233   1   40.77  ? 189 LEU A CB  1 
ATOM   1542 C  CG  . LEU A 1 193 ? -10.117 -30.501 7.146   1   46.54  ? 189 LEU A CG  1 
ATOM   1543 C  CD1 . LEU A 1 193 ? -11.584 -30.892 7.003   1   46.04  ? 189 LEU A CD1 1 
ATOM   1544 C  CD2 . LEU A 1 193 ? -9.615  -30.7   8.578   1   54.51  ? 189 LEU A CD2 1 
ATOM   1545 N  N   . GLY A 1 194 ? -7.04   -33.032 4.701   1   39.79  ? 190 GLY A N   1 
ATOM   1546 C  CA  . GLY A 1 194 ? -6.424  -34.246 4.197   1   40.52  ? 190 GLY A CA  1 
ATOM   1547 C  C   . GLY A 1 194 ? -5.108  -34.549 4.918   1   42.06  ? 190 GLY A C   1 
ATOM   1548 O  O   . GLY A 1 194 ? -4.917  -35.66  5.413   1   42.32  ? 190 GLY A O   1 
ATOM   1549 N  N   . CYS A 1 195 ? -4.223  -33.542 4.997   1   41     ? 191 CYS A N   1 
ATOM   1550 C  CA  . CYS A 1 195 ? -2.948  -33.686 5.677   1   38.29  ? 191 CYS A CA  1 
ATOM   1551 C  C   . CYS A 1 195 ? -3.192  -34.114 7.123   1   41.69  ? 191 CYS A C   1 
ATOM   1552 O  O   . CYS A 1 195 ? -2.505  -35.011 7.597   1   38.94  ? 191 CYS A O   1 
ATOM   1553 C  CB  . CYS A 1 195 ? -2.141  -32.4   5.577   1   36.94  ? 191 CYS A CB  1 
ATOM   1554 S  SG  . CYS A 1 195 ? -1.577  -32.01  3.899   1   40.81  ? 191 CYS A SG  1 
ATOM   1555 N  N   . ILE A 1 196 ? -4.193  -33.504 7.798   1   41.08  ? 192 ILE A N   1 
ATOM   1556 C  CA  . ILE A 1 196 ? -4.515  -33.765 9.194   1   38.86  ? 192 ILE A CA  1 
ATOM   1557 C  C   . ILE A 1 196 ? -5.045  -35.193 9.359   1   45.53  ? 192 ILE A C   1 
ATOM   1558 O  O   . ILE A 1 196 ? -4.682  -35.853 10.35   1   44.59  ? 192 ILE A O   1 
ATOM   1559 C  CB  . ILE A 1 196 ? -5.491  -32.705 9.744   1   39.5   ? 192 ILE A CB  1 
ATOM   1560 C  CG1 . ILE A 1 196 ? -4.802  -31.362 9.825   1   42.13  ? 192 ILE A CG1 1 
ATOM   1561 C  CG2 . ILE A 1 196 ? -6.109  -33.092 11.099  1   36     ? 192 ILE A CG2 1 
ATOM   1562 C  CD1 . ILE A 1 196 ? -5.749  -30.197 9.977   1   38.52  ? 192 ILE A CD1 1 
ATOM   1563 N  N   . PHE A 1 197 ? -5.915  -35.637 8.419   1   40.09  ? 193 PHE A N   1 
ATOM   1564 C  CA  . PHE A 1 197 ? -6.465  -36.99  8.407   1   40.78  ? 193 PHE A CA  1 
ATOM   1565 C  C   . PHE A 1 197 ? -5.321  -38.001 8.488   1   43.16  ? 193 PHE A C   1 
ATOM   1566 O  O   . PHE A 1 197 ? -5.271  -38.847 9.391   1   43.76  ? 193 PHE A O   1 
ATOM   1567 C  CB  . PHE A 1 197 ? -7.353  -37.221 7.18    1   39.81  ? 193 PHE A CB  1 
ATOM   1568 C  CG  . PHE A 1 197 ? -8      -38.595 7.014   1   40.84  ? 193 PHE A CG  1 
ATOM   1569 C  CD1 . PHE A 1 197 ? -7.999  -39.541 8.043   1   37.92  ? 193 PHE A CD1 1 
ATOM   1570 C  CD2 . PHE A 1 197 ? -8.617  -38.943 5.809   1   39.55  ? 193 PHE A CD2 1 
ATOM   1571 C  CE1 . PHE A 1 197 ? -8.594  -40.792 7.852   1   40.63  ? 193 PHE A CE1 1 
ATOM   1572 C  CE2 . PHE A 1 197 ? -9.217  -40.193 5.623   1   38.32  ? 193 PHE A CE2 1 
ATOM   1573 C  CZ  . PHE A 1 197 ? -9.219  -41.114 6.647   1   40.45  ? 193 PHE A CZ  1 
ATOM   1574 N  N   . ALA A 1 198 ? -4.397  -37.877 7.53    1   41.84  ? 194 ALA A N   1 
ATOM   1575 C  CA  . ALA A 1 198 ? -3.226  -38.737 7.459   1   44.53  ? 194 ALA A CA  1 
ATOM   1576 C  C   . ALA A 1 198 ? -2.48   -38.683 8.795   1   46.22  ? 194 ALA A C   1 
ATOM   1577 O  O   . ALA A 1 198 ? -2.114  -39.729 9.335   1   45.38  ? 194 ALA A O   1 
ATOM   1578 C  CB  . ALA A 1 198 ? -2.357  -38.328 6.278   1   36.87  ? 194 ALA A CB  1 
ATOM   1579 N  N   . GLU A 1 199 ? -2.329  -37.459 9.339   1   44.59  ? 195 GLU A N   1 
ATOM   1580 C  CA  . GLU A 1 199 ? -1.515  -37.195 10.514  1   45.09  ? 195 GLU A CA  1 
ATOM   1581 C  C   . GLU A 1 199 ? -2.124  -37.86  11.749  1   48.77  ? 195 GLU A C   1 
ATOM   1582 O  O   . GLU A 1 199 ? -1.39   -38.327 12.623  1   48.51  ? 195 GLU A O   1 
ATOM   1583 C  CB  . GLU A 1 199 ? -1.279  -35.698 10.717  1   43.4   ? 195 GLU A CB  1 
ATOM   1584 C  CG  . GLU A 1 199 ? -0.295  -35.389 11.848  1   41.99  ? 195 GLU A CG  1 
ATOM   1585 C  CD  . GLU A 1 199 ? 0.228   -33.967 11.903  1   42.64  ? 195 GLU A CD  1 
ATOM   1586 O  OE1 . GLU A 1 199 ? 0.063   -33.278 10.879  1   39.76  ? 195 GLU A OE1 1 
ATOM   1587 O  OE2 . GLU A 1 199 ? 0.743   -33.528 12.97   1   50.09  ? 195 GLU A OE2 1 
ATOM   1588 N  N   . MET A 1 200 ? -3.461  -37.936 11.795  1   48.9   ? 196 MET A N   1 
ATOM   1589 C  CA  . MET A 1 200 ? -4.161  -38.636 12.867  1   46.82  ? 196 MET A CA  1 
ATOM   1590 C  C   . MET A 1 200 ? -3.897  -40.14  12.827  1   44.41  ? 196 MET A C   1 
ATOM   1591 O  O   . MET A 1 200 ? -3.908  -40.765 13.878  1   44.17  ? 196 MET A O   1 
ATOM   1592 C  CB  . MET A 1 200 ? -5.674  -38.372 12.823  1   45.17  ? 196 MET A CB  1 
ATOM   1593 C  CG  . MET A 1 200 ? -6.052  -37.003 13.379  1   41.93  ? 196 MET A CG  1 
ATOM   1594 S  SD  . MET A 1 200 ? -7.826  -36.852 13.646  1   43.21  ? 196 MET A SD  1 
ATOM   1595 C  CE  . MET A 1 200 ? -8.451  -36.622 11.979  1   38.08  ? 196 MET A CE  1 
ATOM   1596 N  N   . VAL A 1 201 ? -3.649  -40.704 11.635  1   44.19  ? 197 VAL A N   1 
ATOM   1597 C  CA  . VAL A 1 201 ? -3.475  -42.14  11.476  1   46.49  ? 197 VAL A CA  1 
ATOM   1598 C  C   . VAL A 1 201 ? -2.064  -42.505 11.926  1   49.67  ? 197 VAL A C   1 
ATOM   1599 O  O   . VAL A 1 201 ? -1.876  -43.44  12.698  1   51.51  ? 197 VAL A O   1 
ATOM   1600 C  CB  . VAL A 1 201 ? -3.78   -42.64  10.043  1   46.02  ? 197 VAL A CB  1 
ATOM   1601 C  CG1 . VAL A 1 201 ? -3.411  -44.106 9.859   1   43.87  ? 197 VAL A CG1 1 
ATOM   1602 C  CG2 . VAL A 1 201 ? -5.239  -42.421 9.659   1   38.89  ? 197 VAL A CG2 1 
ATOM   1603 N  N   . THR A 1 202 ? -1.081  -41.724 11.464  1   52.59  ? 198 THR A N   1 
ATOM   1604 C  CA  . THR A 1 202 ? 0.333   -42.04  11.648  1   56.95  ? 198 THR A CA  1 
ATOM   1605 C  C   . THR A 1 202 ? 0.909   -41.327 12.877  1   56.97  ? 198 THR A C   1 
ATOM   1606 O  O   . THR A 1 202 ? 1.972   -41.7   13.356  1   54.26  ? 198 THR A O   1 
ATOM   1607 C  CB  . THR A 1 202 ? 1.123   -41.663 10.391  1   58.82  ? 198 THR A CB  1 
ATOM   1608 O  OG1 . THR A 1 202 ? 1.19    -40.239 10.407  1   64.22  ? 198 THR A OG1 1 
ATOM   1609 C  CG2 . THR A 1 202 ? 0.453   -42.107 9.099   1   57.7   ? 198 THR A CG2 1 
ATOM   1610 N  N   . ARG A 1 203 ? 0.29    -40.217 13.268  1   56.64  ? 199 ARG A N   1 
ATOM   1611 C  CA  . ARG A 1 203 ? 0.813   -39.376 14.382  1   61.03  ? 199 ARG A CA  1 
ATOM   1612 C  C   . ARG A 1 203 ? 2.07    -38.627 13.903  1   59.88  ? 199 ARG A C   1 
ATOM   1613 O  O   . ARG A 1 203 ? 2.829   -38.174 14.767  1   62.62  ? 199 ARG A O   1 
ATOM   1614 C  CB  . ARG A 1 203 ? 0.961   -40.142 15.703  1   69.49  ? 199 ARG A CB  1 
ATOM   1615 C  CG  . ARG A 1 203 ? -0.342  -40.264 16.477  1   68.88  ? 199 ARG A CG  1 
ATOM   1616 C  CD  . ARG A 1 203 ? -0.787  -41.71  16.523  1   71.46  ? 199 ARG A CD  1 
ATOM   1617 N  NE  . ARG A 1 203 ? 0.255   -42.55  17.122  1   76.41  ? 199 ARG A NE  1 
ATOM   1618 C  CZ  . ARG A 1 203 ? 0.657   -43.715 16.637  1   80.82  ? 199 ARG A CZ  1 
ATOM   1619 N  NH1 . ARG A 1 203 ? 0.067   -44.227 15.575  1   83.82  ? 199 ARG A NH1 1 
ATOM   1620 N  NH2 . ARG A 1 203 ? 1.642   -44.369 17.223  1   82.11  ? 199 ARG A NH2 1 
ATOM   1621 N  N   . ARG A 1 204 ? 2.277   -38.501 12.589  1   58.42  ? 200 ARG A N   1 
ATOM   1622 C  CA  . ARG A 1 204 ? 3.373   -37.67  12.086  1   58.82  ? 200 ARG A CA  1 
ATOM   1623 C  C   . ARG A 1 204 ? 2.933   -36.884 10.843  1   52.7   ? 200 ARG A C   1 
ATOM   1624 O  O   . ARG A 1 204 ? 2.153   -37.385 10.039  1   55.55  ? 200 ARG A O   1 
ATOM   1625 C  CB  . ARG A 1 204 ? 4.642   -38.497 11.842  1   64.37  ? 200 ARG A CB  1 
ATOM   1626 C  CG  . ARG A 1 204 ? 4.435   -39.473 10.697  1   75.85  ? 200 ARG A CG  1 
ATOM   1627 C  CD  . ARG A 1 204 ? 5.698   -40.114 10.125  1   86.25  ? 200 ARG A CD  1 
ATOM   1628 N  NE  . ARG A 1 204 ? 5.377   -40.646 8.791   1   84.27  ? 200 ARG A NE  1 
ATOM   1629 C  CZ  . ARG A 1 204 ? 6.174   -41.407 8.04    1   79.61  ? 200 ARG A CZ  1 
ATOM   1630 N  NH1 . ARG A 1 204 ? 7.366   -41.764 8.473   1   79.62  ? 200 ARG A NH1 1 
ATOM   1631 N  NH2 . ARG A 1 204 ? 5.785   -41.826 6.854   1   73.54  ? 200 ARG A NH2 1 
ATOM   1632 N  N   . ALA A 1 205 ? 3.45    -35.66  10.663  1   45.65  ? 201 ALA A N   1 
ATOM   1633 C  CA  . ALA A 1 205 ? 3.052   -34.837 9.524   1   44.13  ? 201 ALA A CA  1 
ATOM   1634 C  C   . ALA A 1 205 ? 3.287   -35.585 8.208   1   43.92  ? 201 ALA A C   1 
ATOM   1635 O  O   . ALA A 1 205 ? 4.265   -36.309 8.084   1   45.4   ? 201 ALA A O   1 
ATOM   1636 C  CB  . ALA A 1 205 ? 3.747   -33.503 9.545   1   38.94  ? 201 ALA A CB  1 
ATOM   1637 N  N   . LEU A 1 206 ? 2.356   -35.439 7.256   1   41.35  ? 202 LEU A N   1 
ATOM   1638 C  CA  . LEU A 1 206 ? 2.445   -36.092 5.957   1   44.92  ? 202 LEU A CA  1 
ATOM   1639 C  C   . LEU A 1 206 ? 3.501   -35.441 5.057   1   43.33  ? 202 LEU A C   1 
ATOM   1640 O  O   . LEU A 1 206 ? 4.232   -36.143 4.381   1   46.64  ? 202 LEU A O   1 
ATOM   1641 C  CB  . LEU A 1 206 ? 1.069   -36.084 5.29    1   41.72  ? 202 LEU A CB  1 
ATOM   1642 C  CG  . LEU A 1 206 ? 0.943   -36.857 3.974   1   44.33  ? 202 LEU A CG  1 
ATOM   1643 C  CD1 . LEU A 1 206 ? 1.125   -38.357 4.201   1   48.74  ? 202 LEU A CD1 1 
ATOM   1644 C  CD2 . LEU A 1 206 ? -0.406  -36.558 3.364   1   43.7   ? 202 LEU A CD2 1 
ATOM   1645 N  N   . PHE A 1 207 ? 3.584   -34.105 5.04    1   42.07  ? 203 PHE A N   1 
ATOM   1646 C  CA  . PHE A 1 207 ? 4.572   -33.425 4.21    1   40.3   ? 203 PHE A CA  1 
ATOM   1647 C  C   . PHE A 1 207 ? 5.328   -32.367 5.012   1   44.6   ? 203 PHE A C   1 
ATOM   1648 O  O   . PHE A 1 207 ? 5.014   -31.175 4.94    1   50.89  ? 203 PHE A O   1 
ATOM   1649 C  CB  . PHE A 1 207 ? 3.832   -32.745 3.063   1   40.25  ? 203 PHE A CB  1 
ATOM   1650 C  CG  . PHE A 1 207 ? 2.883   -33.639 2.281   1   41.75  ? 203 PHE A CG  1 
ATOM   1651 C  CD1 . PHE A 1 207 ? 3.365   -34.756 1.6     1   41.02  ? 203 PHE A CD1 1 
ATOM   1652 C  CD2 . PHE A 1 207 ? 1.531   -33.327 2.174   1   38.57  ? 203 PHE A CD2 1 
ATOM   1653 C  CE1 . PHE A 1 207 ? 2.516   -35.542 0.848   1   40.68  ? 203 PHE A CE1 1 
ATOM   1654 C  CE2 . PHE A 1 207 ? 0.68    -34.14  1.44    1   42.1   ? 203 PHE A CE2 1 
ATOM   1655 C  CZ  . PHE A 1 207 ? 1.175   -35.229 0.752   1   38.58  ? 203 PHE A CZ  1 
ATOM   1656 N  N   . PRO A 1 208 ? 6.322   -32.767 5.837   1   44.57  ? 204 PRO A N   1 
ATOM   1657 C  CA  . PRO A 1 208 ? 7.042   -31.816 6.69    1   41.38  ? 204 PRO A CA  1 
ATOM   1658 C  C   . PRO A 1 208 ? 8.233   -31.185 5.977   1   41.44  ? 204 PRO A C   1 
ATOM   1659 O  O   . PRO A 1 208 ? 9.39    -31.565 6.206   1   42.38  ? 204 PRO A O   1 
ATOM   1660 C  CB  . PRO A 1 208 ? 7.502   -32.759 7.823   1   40.18  ? 204 PRO A CB  1 
ATOM   1661 C  CG  . PRO A 1 208 ? 7.865   -34.06  7.101   1   38.35  ? 204 PRO A CG  1 
ATOM   1662 C  CD  . PRO A 1 208 ? 6.796   -34.161 6.009   1   42.24  ? 204 PRO A CD  1 
ATOM   1663 N  N   . GLY A 1 209 ? 7.947   -30.238 5.089   1   41.27  ? 205 GLY A N   1 
ATOM   1664 C  CA  . GLY A 1 209 ? 9.022   -29.64  4.304   1   45.83  ? 205 GLY A CA  1 
ATOM   1665 C  C   . GLY A 1 209 ? 9.678   -28.518 5.094   1   45.42  ? 205 GLY A C   1 
ATOM   1666 O  O   . GLY A 1 209 ? 9.051   -28.041 6.035   1   49.52  ? 205 GLY A O   1 
ATOM   1667 N  N   . ASP A 1 210 ? 10.875  -28.076 4.682   1   52.21  ? 206 ASP A N   1 
ATOM   1668 C  CA  . ASP A 1 210 ? 11.584  -26.998 5.371   1   62.31  ? 206 ASP A CA  1 
ATOM   1669 C  C   . ASP A 1 210 ? 11.703  -25.749 4.499   1   58.07  ? 206 ASP A C   1 
ATOM   1670 O  O   . ASP A 1 210 ? 12.31   -24.783 4.934   1   64.57  ? 206 ASP A O   1 
ATOM   1671 C  CB  . ASP A 1 210 ? 12.885  -27.481 5.992   1   67.03  ? 206 ASP A CB  1 
ATOM   1672 C  CG  . ASP A 1 210 ? 13.894  -27.931 4.951   1   82.52  ? 206 ASP A CG  1 
ATOM   1673 O  OD1 . ASP A 1 210 ? 13.63   -27.7   3.755   1   104.68 ? 206 ASP A OD1 1 
ATOM   1674 O  OD2 . ASP A 1 210 ? 14.894  -28.571 5.338   1   76.97  ? 206 ASP A OD2 1 
ATOM   1675 N  N   . SER A 1 211 ? 11.061  -25.748 3.319   1   53.38  ? 207 SER A N   1 
ATOM   1676 C  CA  . SER A 1 211 ? 10.938  -24.558 2.486   1   51.71  ? 207 SER A CA  1 
ATOM   1677 C  C   . SER A 1 211 ? 9.778   -24.72  1.508   1   49.39  ? 207 SER A C   1 
ATOM   1678 O  O   . SER A 1 211 ? 9.256   -25.811 1.377   1   49.42  ? 207 SER A O   1 
ATOM   1679 C  CB  . SER A 1 211 ? 12.221  -24.284 1.759   1   51.29  ? 207 SER A CB  1 
ATOM   1680 O  OG  . SER A 1 211 ? 12.666  -25.448 1.09    1   55.26  ? 207 SER A OG  1 
ATOM   1681 N  N   . GLU A 1 212 ? 9.399   -23.667 0.773   1   49.51  ? 208 GLU A N   1 
ATOM   1682 C  CA  . GLU A 1 212 ? 8.352   -23.847 -0.226  1   51.93  ? 208 GLU A CA  1 
ATOM   1683 C  C   . GLU A 1 212 ? 8.709   -24.968 -1.207  1   49.33  ? 208 GLU A C   1 
ATOM   1684 O  O   . GLU A 1 212 ? 7.896   -25.845 -1.453  1   44.56  ? 208 GLU A O   1 
ATOM   1685 C  CB  . GLU A 1 212 ? 8.041   -22.55  -0.967  1   52.75  ? 208 GLU A CB  1 
ATOM   1686 C  CG  . GLU A 1 212 ? 7.331   -21.525 -0.086  1   56.96  ? 208 GLU A CG  1 
ATOM   1687 C  CD  . GLU A 1 212 ? 7.083   -20.225 -0.822  1   62.39  ? 208 GLU A CD  1 
ATOM   1688 O  OE1 . GLU A 1 212 ? 6.013   -20.088 -1.442  1   64.73  ? 208 GLU A OE1 1 
ATOM   1689 O  OE2 . GLU A 1 212 ? 8.006   -19.389 -0.819  1   65.86  ? 208 GLU A OE2 1 
ATOM   1690 N  N   . ILE A 1 213 ? 9.934   -24.958 -1.746  1   49.03  ? 209 ILE A N   1 
ATOM   1691 C  CA  . ILE A 1 213 ? 10.313  -25.887 -2.804  1   49.95  ? 209 ILE A CA  1 
ATOM   1692 C  C   . ILE A 1 213 ? 10.443  -27.326 -2.275  1   53.36  ? 209 ILE A C   1 
ATOM   1693 O  O   . ILE A 1 213 ? 10.151  -28.283 -3.003  1   52.96  ? 209 ILE A O   1 
ATOM   1694 C  CB  . ILE A 1 213 ? 11.581  -25.393 -3.536  1   49.67  ? 209 ILE A CB  1 
ATOM   1695 C  CG1 . ILE A 1 213 ? 11.741  -26.045 -4.889  1   50.84  ? 209 ILE A CG1 1 
ATOM   1696 C  CG2 . ILE A 1 213 ? 12.821  -25.631 -2.691  1   51.08  ? 209 ILE A CG2 1 
ATOM   1697 C  CD1 . ILE A 1 213 ? 10.579  -25.801 -5.836  1   46.12  ? 209 ILE A CD1 1 
ATOM   1698 N  N   . ASP A 1 214 ? 10.889  -27.491 -1.017  1   50.79  ? 210 ASP A N   1 
ATOM   1699 C  CA  . ASP A 1 214 ? 10.947  -28.795 -0.379  1   47.39  ? 210 ASP A CA  1 
ATOM   1700 C  C   . ASP A 1 214 ? 9.553   -29.37  -0.096  1   51.15  ? 210 ASP A C   1 
ATOM   1701 O  O   . ASP A 1 214 ? 9.345   -30.587 -0.189  1   56.24  ? 210 ASP A O   1 
ATOM   1702 C  CB  . ASP A 1 214 ? 11.822  -28.755 0.855   1   49.58  ? 210 ASP A CB  1 
ATOM   1703 C  CG  . ASP A 1 214 ? 12.01   -30.109 1.527   1   57.52  ? 210 ASP A CG  1 
ATOM   1704 O  OD1 . ASP A 1 214 ? 12.449  -31.074 0.816   1   56.54  ? 210 ASP A OD1 1 
ATOM   1705 O  OD2 . ASP A 1 214 ? 11.702  -30.189 2.743   1   54.46  ? 210 ASP A OD2 1 
ATOM   1706 N  N   . GLN A 1 215 ? 8.6     -28.508 0.298   1   49.14  ? 211 GLN A N   1 
ATOM   1707 C  CA  . GLN A 1 215 ? 7.221   -28.917 0.511   1   48.18  ? 211 GLN A CA  1 
ATOM   1708 C  C   . GLN A 1 215 ? 6.66    -29.507 -0.789  1   44.83  ? 211 GLN A C   1 
ATOM   1709 O  O   . GLN A 1 215 ? 6.097   -30.59  -0.766  1   47.53  ? 211 GLN A O   1 
ATOM   1710 C  CB  . GLN A 1 215 ? 6.392   -27.744 1.04    1   44.49  ? 211 GLN A CB  1 
ATOM   1711 C  CG  . GLN A 1 215 ? 4.985   -28.133 1.472   1   44.35  ? 211 GLN A CG  1 
ATOM   1712 C  CD  . GLN A 1 215 ? 5.021   -28.871 2.785   1   48.15  ? 211 GLN A CD  1 
ATOM   1713 O  OE1 . GLN A 1 215 ? 5.918   -28.648 3.604   1   50.72  ? 211 GLN A OE1 1 
ATOM   1714 N  NE2 . GLN A 1 215 ? 4.028   -29.713 3.012   1   45.61  ? 211 GLN A NE2 1 
ATOM   1715 N  N   . LEU A 1 216 ? 6.856   -28.808 -1.914  1   43.03  ? 212 LEU A N   1 
ATOM   1716 C  CA  . LEU A 1 216 ? 6.373   -29.235 -3.217  1   45.77  ? 212 LEU A CA  1 
ATOM   1717 C  C   . LEU A 1 216 ? 6.966   -30.591 -3.582  1   47.06  ? 212 LEU A C   1 
ATOM   1718 O  O   . LEU A 1 216 ? 6.244   -31.452 -4.081  1   45.55  ? 212 LEU A O   1 
ATOM   1719 C  CB  . LEU A 1 216 ? 6.696   -28.232 -4.323  1   46.62  ? 212 LEU A CB  1 
ATOM   1720 C  CG  . LEU A 1 216 ? 5.63    -27.172 -4.587  1   58.14  ? 212 LEU A CG  1 
ATOM   1721 C  CD1 . LEU A 1 216 ? 6.193   -26.118 -5.552  1   60.31  ? 212 LEU A CD1 1 
ATOM   1722 C  CD2 . LEU A 1 216 ? 4.381   -27.821 -5.133  1   50.42  ? 212 LEU A CD2 1 
ATOM   1723 N  N   . PHE A 1 217 ? 8.286   -30.724 -3.385  1   42.76  ? 213 PHE A N   1 
ATOM   1724 C  CA  . PHE A 1 217 ? 9.022   -31.93  -3.717  1   41.63  ? 213 PHE A CA  1 
ATOM   1725 C  C   . PHE A 1 217 ? 8.527   -33.12  -2.895  1   44.07  ? 213 PHE A C   1 
ATOM   1726 O  O   . PHE A 1 217 ? 8.348   -34.196 -3.455  1   52.09  ? 213 PHE A O   1 
ATOM   1727 C  CB  . PHE A 1 217 ? 10.54   -31.712 -3.688  1   41.16  ? 213 PHE A CB  1 
ATOM   1728 C  CG  . PHE A 1 217 ? 11.082  -30.935 -4.872  1   41.4   ? 213 PHE A CG  1 
ATOM   1729 C  CD1 . PHE A 1 217 ? 10.218  -30.355 -5.809  1   38.66  ? 213 PHE A CD1 1 
ATOM   1730 C  CD2 . PHE A 1 217 ? 12.452  -30.738 -5.022  1   42.6   ? 213 PHE A CD2 1 
ATOM   1731 C  CE1 . PHE A 1 217 ? 10.727  -29.624 -6.877  1   40.34  ? 213 PHE A CE1 1 
ATOM   1732 C  CE2 . PHE A 1 217 ? 12.954  -29.99  -6.095  1   41.37  ? 213 PHE A CE2 1 
ATOM   1733 C  CZ  . PHE A 1 217 ? 12.094  -29.431 -7.019  1   38.97  ? 213 PHE A CZ  1 
ATOM   1734 N  N   . ARG A 1 218 ? 8.275   -32.937 -1.591  1   43.36  ? 214 ARG A N   1 
ATOM   1735 C  CA  . ARG A 1 218 ? 7.759   -34.016 -0.752  1   45.93  ? 214 ARG A CA  1 
ATOM   1736 C  C   . ARG A 1 218 ? 6.344   -34.434 -1.173  1   43.79  ? 214 ARG A C   1 
ATOM   1737 O  O   . ARG A 1 218 ? 6.015   -35.619 -1.113  1   50.64  ? 214 ARG A O   1 
ATOM   1738 C  CB  . ARG A 1 218 ? 7.8     -33.65  0.74    1   44.88  ? 214 ARG A CB  1 
ATOM   1739 C  CG  . ARG A 1 218 ? 9.197   -33.562 1.333   1   47.26  ? 214 ARG A CG  1 
ATOM   1740 C  CD  . ARG A 1 218 ? 9.103   -32.906 2.689   1   43.46  ? 214 ARG A CD  1 
ATOM   1741 N  NE  . ARG A 1 218 ? 10.446  -32.748 3.26    1   44.76  ? 214 ARG A NE  1 
ATOM   1742 C  CZ  . ARG A 1 218 ? 10.941  -33.56  4.194   1   46.12  ? 214 ARG A CZ  1 
ATOM   1743 N  NH1 . ARG A 1 218 ? 10.35   -34.725 4.454   1   44.28  ? 214 ARG A NH1 1 
ATOM   1744 N  NH2 . ARG A 1 218 ? 12.04   -33.203 4.839   1   40.8   ? 214 ARG A NH2 1 
ATOM   1745 N  N   . ILE A 1 219 ? 5.519   -33.466 -1.601  1   40.14  ? 215 ILE A N   1 
ATOM   1746 C  CA  . ILE A 1 219 ? 4.187   -33.754 -2.105  1   40.38  ? 215 ILE A CA  1 
ATOM   1747 C  C   . ILE A 1 219 ? 4.272   -34.555 -3.409  1   43.67  ? 215 ILE A C   1 
ATOM   1748 O  O   . ILE A 1 219 ? 3.603   -35.582 -3.522  1   45     ? 215 ILE A O   1 
ATOM   1749 C  CB  . ILE A 1 219 ? 3.363   -32.471 -2.257  1   36.06  ? 215 ILE A CB  1 
ATOM   1750 C  CG1 . ILE A 1 219 ? 3.072   -31.864 -0.887  1   38.38  ? 215 ILE A CG1 1 
ATOM   1751 C  CG2 . ILE A 1 219 ? 2.058   -32.755 -3.01   1   33.9   ? 215 ILE A CG2 1 
ATOM   1752 C  CD1 . ILE A 1 219 ? 2.616   -30.405 -0.965  1   36.83  ? 215 ILE A CD1 1 
ATOM   1753 N  N   . PHE A 1 220 ? 5.092   -34.075 -4.359  1   40.92  ? 216 PHE A N   1 
ATOM   1754 C  CA  . PHE A 1 220 ? 5.323   -34.687 -5.663  1   43.6   ? 216 PHE A CA  1 
ATOM   1755 C  C   . PHE A 1 220 ? 5.883   -36.107 -5.505  1   42.71  ? 216 PHE A C   1 
ATOM   1756 O  O   . PHE A 1 220 ? 5.548   -36.991 -6.295  1   43.35  ? 216 PHE A O   1 
ATOM   1757 C  CB  . PHE A 1 220 ? 6.289   -33.852 -6.524  1   39.36  ? 216 PHE A CB  1 
ATOM   1758 C  CG  . PHE A 1 220 ? 5.818   -32.498 -7.04   1   38.22  ? 216 PHE A CG  1 
ATOM   1759 C  CD1 . PHE A 1 220 ? 4.581   -31.974 -6.689  1   37.03  ? 216 PHE A CD1 1 
ATOM   1760 C  CD2 . PHE A 1 220 ? 6.648   -31.736 -7.86   1   40.37  ? 216 PHE A CD2 1 
ATOM   1761 C  CE1 . PHE A 1 220 ? 4.184   -30.727 -7.156  1   39.5   ? 216 PHE A CE1 1 
ATOM   1762 C  CE2 . PHE A 1 220 ? 6.243   -30.494 -8.334  1   40.84  ? 216 PHE A CE2 1 
ATOM   1763 C  CZ  . PHE A 1 220 ? 5.021   -29.979 -7.963  1   38.58  ? 216 PHE A CZ  1 
ATOM   1764 N  N   . ARG A 1 221 ? 6.735   -36.306 -4.508  1   39.53  ? 217 ARG A N   1 
ATOM   1765 C  CA  . ARG A 1 221 ? 7.36    -37.632 -4.299  1   39.57  ? 217 ARG A CA  1 
ATOM   1766 C  C   . ARG A 1 221 ? 6.317   -38.6   -3.736  1   41.13  ? 217 ARG A C   1 
ATOM   1767 O  O   . ARG A 1 221 ? 6.502   -39.814 -3.894  1   49.91  ? 217 ARG A O   1 
ATOM   1768 C  CB  . ARG A 1 221 ? 8.578   -37.494 -3.386  1   38.08  ? 217 ARG A CB  1 
ATOM   1769 C  CG  . ARG A 1 221 ? 9.833   -37.005 -4.088  1   38.79  ? 217 ARG A CG  1 
ATOM   1770 C  CD  . ARG A 1 221 ? 11.105  -37.303 -3.326  1   42.26  ? 217 ARG A CD  1 
ATOM   1771 N  NE  . ARG A 1 221 ? 11.225  -36.462 -2.132  1   49.83  ? 217 ARG A NE  1 
ATOM   1772 C  CZ  . ARG A 1 221 ? 11.765  -35.255 -2.102  1   51.03  ? 217 ARG A CZ  1 
ATOM   1773 N  NH1 . ARG A 1 221 ? 11.728  -34.552 -0.988  1   48.84  ? 217 ARG A NH1 1 
ATOM   1774 N  NH2 . ARG A 1 221 ? 12.341  -34.755 -3.177  1   45.32  ? 217 ARG A NH2 1 
ATOM   1775 N  N   . THR A 1 222 ? 5.257   -38.074 -3.128  1   43.65  ? 218 THR A N   1 
ATOM   1776 C  CA  . THR A 1 222 ? 4.229   -38.924 -2.554  1   44.2   ? 218 THR A CA  1 
ATOM   1777 C  C   . THR A 1 222 ? 3.084   -39.134 -3.547  1   46.92  ? 218 THR A C   1 
ATOM   1778 O  O   . THR A 1 222 ? 2.539   -40.219 -3.623  1   59.45  ? 218 THR A O   1 
ATOM   1779 C  CB  . THR A 1 222 ? 3.726   -38.325 -1.237  1   46.53  ? 218 THR A CB  1 
ATOM   1780 O  OG1 . THR A 1 222 ? 4.849   -38.249 -0.358  1   45.75  ? 218 THR A OG1 1 
ATOM   1781 C  CG2 . THR A 1 222 ? 2.582   -39.111 -0.62   1   43.52  ? 218 THR A CG2 1 
ATOM   1782 N  N   . LEU A 1 223 ? 2.676   -38.096 -4.269  1   41.8   ? 219 LEU A N   1 
ATOM   1783 C  CA  . LEU A 1 223 ? 1.471   -38.151 -5.069  1   45.57  ? 219 LEU A CA  1 
ATOM   1784 C  C   . LEU A 1 223 ? 1.806   -38.203 -6.56   1   47.32  ? 219 LEU A C   1 
ATOM   1785 O  O   . LEU A 1 223 ? 0.904   -38.284 -7.401  1   47.49  ? 219 LEU A O   1 
ATOM   1786 C  CB  . LEU A 1 223 ? 0.636   -36.917 -4.723  1   49.43  ? 219 LEU A CB  1 
ATOM   1787 C  CG  . LEU A 1 223 ? 0.175   -36.798 -3.262  1   51.2   ? 219 LEU A CG  1 
ATOM   1788 C  CD1 . LEU A 1 223 ? -0.704  -35.579 -3.076  1   45.27  ? 219 LEU A CD1 1 
ATOM   1789 C  CD2 . LEU A 1 223 ? -0.583  -38.041 -2.805  1   53.78  ? 219 LEU A CD2 1 
ATOM   1790 N  N   . GLY A 1 224 ? 3.107   -38.142 -6.86   1   43.25  ? 220 GLY A N   1 
ATOM   1791 C  CA  . GLY A 1 224 ? 3.614   -38.026 -8.217  1   41.66  ? 220 GLY A CA  1 
ATOM   1792 C  C   . GLY A 1 224 ? 3.683   -36.558 -8.629  1   42.28  ? 220 GLY A C   1 
ATOM   1793 O  O   . GLY A 1 224 ? 2.954   -35.73  -8.1    1   39.18  ? 220 GLY A O   1 
ATOM   1794 N  N   . THR A 1 225 ? 4.591   -36.244 -9.558  1   43.1   ? 221 THR A N   1 
ATOM   1795 C  CA  . THR A 1 225 ? 4.709   -34.884 -10.044 1   45.4   ? 221 THR A CA  1 
ATOM   1796 C  C   . THR A 1 225 ? 3.529   -34.65  -10.975 1   49.37  ? 221 THR A C   1 
ATOM   1797 O  O   . THR A 1 225 ? 3.344   -35.385 -11.925 1   56.17  ? 221 THR A O   1 
ATOM   1798 C  CB  . THR A 1 225 ? 6.028   -34.675 -10.783 1   50.23  ? 221 THR A CB  1 
ATOM   1799 O  OG1 . THR A 1 225 ? 7.122   -34.989 -9.923  1   53.71  ? 221 THR A OG1 1 
ATOM   1800 C  CG2 . THR A 1 225 ? 6.178   -33.261 -11.321 1   47.96  ? 221 THR A CG2 1 
ATOM   1801 N  N   . PRO A 1 226 ? 2.704   -33.612 -10.76  1   54.06  ? 222 PRO A N   1 
ATOM   1802 C  CA  . PRO A 1 226 ? 1.501   -33.431 -11.579 1   50.19  ? 222 PRO A CA  1 
ATOM   1803 C  C   . PRO A 1 226 ? 1.872   -32.954 -12.978 1   49.79  ? 222 PRO A C   1 
ATOM   1804 O  O   . PRO A 1 226 ? 2.881   -32.276 -13.153 1   50.39  ? 222 PRO A O   1 
ATOM   1805 C  CB  . PRO A 1 226 ? 0.743   -32.354 -10.782 1   50.96  ? 222 PRO A CB  1 
ATOM   1806 C  CG  . PRO A 1 226 ? 1.852   -31.545 -10.125 1   51.9   ? 222 PRO A CG  1 
ATOM   1807 C  CD  . PRO A 1 226 ? 2.915   -32.559 -9.752  1   50.47  ? 222 PRO A CD  1 
ATOM   1808 N  N   . ASP A 1 227 ? 1.071   -33.366 -13.966 1   52.66  ? 223 ASP A N   1 
ATOM   1809 C  CA  . ASP A 1 227 ? 1.156   -32.912 -15.349 1   55.14  ? 223 ASP A CA  1 
ATOM   1810 C  C   . ASP A 1 227 ? -0.228  -32.448 -15.823 1   53.95  ? 223 ASP A C   1 
ATOM   1811 O  O   . ASP A 1 227 ? -1.211  -32.462 -15.07  1   43.94  ? 223 ASP A O   1 
ATOM   1812 C  CB  . ASP A 1 227 ? 1.666   -34.045 -16.231 1   54.21  ? 223 ASP A CB  1 
ATOM   1813 C  CG  . ASP A 1 227 ? 0.769   -35.272 -16.207 1   65.25  ? 223 ASP A CG  1 
ATOM   1814 O  OD1 . ASP A 1 227 ? -0.442  -35.105 -15.936 1   66.81  ? 223 ASP A OD1 1 
ATOM   1815 O  OD2 . ASP A 1 227 ? 1.284   -36.387 -16.428 1   74.59  ? 223 ASP A OD2 1 
ATOM   1816 N  N   . GLU A 1 228 ? -0.319  -32.128 -17.122 1   56.83  ? 224 GLU A N   1 
ATOM   1817 C  CA  . GLU A 1 228 ? -1.522  -31.561 -17.721 1   54.78  ? 224 GLU A CA  1 
ATOM   1818 C  C   . GLU A 1 228 ? -2.699  -32.534 -17.637 1   55.21  ? 224 GLU A C   1 
ATOM   1819 O  O   . GLU A 1 228 ? -3.838  -32.108 -17.459 1   62.44  ? 224 GLU A O   1 
ATOM   1820 C  CB  . GLU A 1 228 ? -1.215  -31.042 -19.126 1   54.29  ? 224 GLU A CB  1 
ATOM   1821 C  CG  . GLU A 1 228 ? -0.339  -29.792 -19.145 1   52.87  ? 224 GLU A CG  1 
ATOM   1822 C  CD  . GLU A 1 228 ? -1.091  -28.554 -18.65  1   62.28  ? 224 GLU A CD  1 
ATOM   1823 O  OE1 . GLU A 1 228 ? -2.35   -28.589 -18.62  1   56.42  ? 224 GLU A OE1 1 
ATOM   1824 O  OE2 . GLU A 1 228 ? -0.438  -27.554 -18.262 1   60.31  ? 224 GLU A OE2 1 
ATOM   1825 N  N   . VAL A 1 229 ? -2.416  -33.838 -17.664 1   56.76  ? 225 VAL A N   1 
ATOM   1826 C  CA  . VAL A 1 229 ? -3.446  -34.87  -17.591 1   58.31  ? 225 VAL A CA  1 
ATOM   1827 C  C   . VAL A 1 229 ? -4.106  -34.874 -16.213 1   60.15  ? 225 VAL A C   1 
ATOM   1828 O  O   . VAL A 1 229 ? -5.324  -34.863 -16.129 1   65.7   ? 225 VAL A O   1 
ATOM   1829 C  CB  . VAL A 1 229 ? -2.919  -36.283 -17.902 1   57.73  ? 225 VAL A CB  1 
ATOM   1830 C  CG1 . VAL A 1 229 ? -4.038  -37.315 -17.81  1   54.47  ? 225 VAL A CG1 1 
ATOM   1831 C  CG2 . VAL A 1 229 ? -2.185  -36.338 -19.24  1   55.98  ? 225 VAL A CG2 1 
ATOM   1832 N  N   . VAL A 1 230 ? -3.314  -34.959 -15.136 1   56.31  ? 226 VAL A N   1 
ATOM   1833 C  CA  . VAL A 1 230 ? -3.905  -35.032 -13.815 1   54.05  ? 226 VAL A CA  1 
ATOM   1834 C  C   . VAL A 1 230 ? -4.424  -33.648 -13.4   1   54.36  ? 226 VAL A C   1 
ATOM   1835 O  O   . VAL A 1 230 ? -5.419  -33.529 -12.687 1   53.08  ? 226 VAL A O   1 
ATOM   1836 C  CB  . VAL A 1 230 ? -2.896  -35.625 -12.817 1   56.48  ? 226 VAL A CB  1 
ATOM   1837 C  CG1 . VAL A 1 230 ? -1.665  -34.75  -12.731 1   64.84  ? 226 VAL A CG1 1 
ATOM   1838 C  CG2 . VAL A 1 230 ? -3.493  -35.816 -11.424 1   62.41  ? 226 VAL A CG2 1 
ATOM   1839 N  N   . TRP A 1 231 ? -3.772  -32.583 -13.864 1   55.87  ? 227 TRP A N   1 
ATOM   1840 C  CA  . TRP A 1 231 ? -4.109  -31.249 -13.384 1   55.27  ? 227 TRP A CA  1 
ATOM   1841 C  C   . TRP A 1 231 ? -3.98   -30.261 -14.542 1   54.01  ? 227 TRP A C   1 
ATOM   1842 O  O   . TRP A 1 231 ? -2.922  -29.68  -14.765 1   56.21  ? 227 TRP A O   1 
ATOM   1843 C  CB  . TRP A 1 231 ? -3.203  -30.88  -12.195 1   53.18  ? 227 TRP A CB  1 
ATOM   1844 C  CG  . TRP A 1 231 ? -3.507  -29.566 -11.525 1   51.69  ? 227 TRP A CG  1 
ATOM   1845 C  CD1 . TRP A 1 231 ? -4.51   -28.701 -11.839 1   48.99  ? 227 TRP A CD1 1 
ATOM   1846 C  CD2 . TRP A 1 231 ? -2.792  -28.977 -10.417 1   50.01  ? 227 TRP A CD2 1 
ATOM   1847 N  NE1 . TRP A 1 231 ? -4.477  -27.621 -11.003 1   49.74  ? 227 TRP A NE1 1 
ATOM   1848 C  CE2 . TRP A 1 231 ? -3.434  -27.759 -10.124 1   47.77  ? 227 TRP A CE2 1 
ATOM   1849 C  CE3 . TRP A 1 231 ? -1.679  -29.356 -9.657  1   48.06  ? 227 TRP A CE3 1 
ATOM   1850 C  CZ2 . TRP A 1 231 ? -3.006  -26.923 -9.101  1   44.66  ? 227 TRP A CZ2 1 
ATOM   1851 C  CZ3 . TRP A 1 231 ? -1.245  -28.527 -8.655  1   47.4   ? 227 TRP A CZ3 1 
ATOM   1852 C  CH2 . TRP A 1 231 ? -1.914  -27.335 -8.375  1   52.21  ? 227 TRP A CH2 1 
ATOM   1853 N  N   . PRO A 1 232 ? -5.038  -30.067 -15.355 1   59.13  ? 228 PRO A N   1 
ATOM   1854 C  CA  . PRO A 1 232 ? -4.95   -29.135 -16.486 1   58.2   ? 228 PRO A CA  1 
ATOM   1855 C  C   . PRO A 1 232 ? -4.592  -27.743 -15.963 1   52.83  ? 228 PRO A C   1 
ATOM   1856 O  O   . PRO A 1 232 ? -5.177  -27.316 -14.973 1   49.49  ? 228 PRO A O   1 
ATOM   1857 C  CB  . PRO A 1 232 ? -6.349  -29.208 -17.133 1   53.83  ? 228 PRO A CB  1 
ATOM   1858 C  CG  . PRO A 1 232 ? -6.916  -30.526 -16.637 1   54.69  ? 228 PRO A CG  1 
ATOM   1859 C  CD  . PRO A 1 232 ? -6.335  -30.757 -15.249 1   56.98  ? 228 PRO A CD  1 
ATOM   1860 N  N   . GLY A 1 233 ? -3.597  -27.087 -16.597 1   56     ? 229 GLY A N   1 
ATOM   1861 C  CA  . GLY A 1 233 ? -3.138  -25.747 -16.238 1   56.46  ? 229 GLY A CA  1 
ATOM   1862 C  C   . GLY A 1 233 ? -1.861  -25.71  -15.39  1   57.54  ? 229 GLY A C   1 
ATOM   1863 O  O   . GLY A 1 233 ? -1.175  -24.695 -15.341 1   65.49  ? 229 GLY A O   1 
ATOM   1864 N  N   . VAL A 1 234 ? -1.511  -26.83  -14.754 1   57.24  ? 230 VAL A N   1 
ATOM   1865 C  CA  . VAL A 1 234 ? -0.445  -26.871 -13.772 1   50.53  ? 230 VAL A CA  1 
ATOM   1866 C  C   . VAL A 1 234 ? 0.821   -26.28  -14.396 1   59.88  ? 230 VAL A C   1 
ATOM   1867 O  O   . VAL A 1 234 ? 1.476   -25.431 -13.791 1   63.18  ? 230 VAL A O   1 
ATOM   1868 C  CB  . VAL A 1 234 ? -0.251  -28.279 -13.168 1   45.09  ? 230 VAL A CB  1 
ATOM   1869 C  CG1 . VAL A 1 234 ? 0.315   -29.295 -14.152 1   45.05  ? 230 VAL A CG1 1 
ATOM   1870 C  CG2 . VAL A 1 234 ? 0.641   -28.255 -11.943 1   45.73  ? 230 VAL A CG2 1 
ATOM   1871 N  N   . THR A 1 235 ? 1.155   -26.709 -15.62  1   59.91  ? 231 THR A N   1 
ATOM   1872 C  CA  . THR A 1 235 ? 2.441   -26.341 -16.208 1   60.03  ? 231 THR A CA  1 
ATOM   1873 C  C   . THR A 1 235 ? 2.464   -24.865 -16.61  1   62.58  ? 231 THR A C   1 
ATOM   1874 O  O   . THR A 1 235 ? 3.508   -24.404 -17.066 1   71.48  ? 231 THR A O   1 
ATOM   1875 C  CB  . THR A 1 235 ? 2.817   -27.191 -17.424 1   55.42  ? 231 THR A CB  1 
ATOM   1876 O  OG1 . THR A 1 235 ? 1.856   -26.809 -18.398 1   59.35  ? 231 THR A OG1 1 
ATOM   1877 C  CG2 . THR A 1 235 ? 2.795   -28.691 -17.195 1   50.3   ? 231 THR A CG2 1 
ATOM   1878 N  N   . SER A 1 236 ? 1.331   -24.153 -16.504 1   56.93  ? 232 SER A N   1 
ATOM   1879 C  CA  . SER A 1 236 ? 1.258   -22.733 -16.838 1   65.8   ? 232 SER A CA  1 
ATOM   1880 C  C   . SER A 1 236 ? 1.422   -21.877 -15.586 1   69.91  ? 232 SER A C   1 
ATOM   1881 O  O   . SER A 1 236 ? 1.707   -20.692 -15.681 1   80.92  ? 232 SER A O   1 
ATOM   1882 C  CB  . SER A 1 236 ? -0.053  -22.359 -17.515 1   72.2   ? 232 SER A CB  1 
ATOM   1883 O  OG  . SER A 1 236 ? -0.006  -22.636 -18.906 1   89.12  ? 232 SER A OG  1 
ATOM   1884 N  N   . MET A 1 237 ? 1.216   -22.483 -14.42  1   67.66  ? 233 MET A N   1 
ATOM   1885 C  CA  . MET A 1 237 ? 1.183   -21.781 -13.144 1   63.54  ? 233 MET A CA  1 
ATOM   1886 C  C   . MET A 1 237 ? 2.471   -20.995 -12.837 1   56.99  ? 233 MET A C   1 
ATOM   1887 O  O   . MET A 1 237 ? 3.587   -21.452 -13.104 1   53.62  ? 233 MET A O   1 
ATOM   1888 C  CB  . MET A 1 237 ? 0.785   -22.778 -12.054 1   58.84  ? 233 MET A CB  1 
ATOM   1889 C  CG  . MET A 1 237 ? -0.694  -22.986 -12.079 1   68.87  ? 233 MET A CG  1 
ATOM   1890 S  SD  . MET A 1 237 ? -1.421  -24.455 -11.349 1   71.49  ? 233 MET A SD  1 
ATOM   1891 C  CE  . MET A 1 237 ? -0.644  -24.457 -9.73   1   102.51 ? 233 MET A CE  1 
ATOM   1892 N  N   . PRO A 1 238 ? 2.343   -19.792 -12.227 1   52.18  ? 234 PRO A N   1 
ATOM   1893 C  CA  . PRO A 1 238 ? 3.456   -18.848 -12.118 1   51.26  ? 234 PRO A CA  1 
ATOM   1894 C  C   . PRO A 1 238 ? 4.78    -19.393 -11.598 1   52.22  ? 234 PRO A C   1 
ATOM   1895 O  O   . PRO A 1 238 ? 5.829   -18.952 -12.064 1   61.2   ? 234 PRO A O   1 
ATOM   1896 C  CB  . PRO A 1 238 ? 2.902   -17.75  -11.197 1   50.67  ? 234 PRO A CB  1 
ATOM   1897 C  CG  . PRO A 1 238 ? 1.402   -17.807 -11.401 1   50.69  ? 234 PRO A CG  1 
ATOM   1898 C  CD  . PRO A 1 238 ? 1.112   -19.283 -11.586 1   50.61  ? 234 PRO A CD  1 
ATOM   1899 N  N   . ASP A 1 239 ? 4.738   -20.326 -10.633 1   49.58  ? 235 ASP A N   1 
ATOM   1900 C  CA  . ASP A 1 239 ? 5.956   -20.852 -10.026 1   54.4   ? 235 ASP A CA  1 
ATOM   1901 C  C   . ASP A 1 239 ? 6.137   -22.326 -10.361 1   56.88  ? 235 ASP A C   1 
ATOM   1902 O  O   . ASP A 1 239 ? 6.909   -23.015 -9.689  1   62.35  ? 235 ASP A O   1 
ATOM   1903 C  CB  . ASP A 1 239 ? 6.017   -20.557 -8.534  1   55.99  ? 235 ASP A CB  1 
ATOM   1904 C  CG  . ASP A 1 239 ? 6       -19.071 -8.219  1   63.38  ? 235 ASP A CG  1 
ATOM   1905 O  OD1 . ASP A 1 239 ? 6.422   -18.278 -9.099  1   65.85  ? 235 ASP A OD1 1 
ATOM   1906 O  OD2 . ASP A 1 239 ? 5.484   -18.707 -7.154  1   69.9   ? 235 ASP A OD2 1 
ATOM   1907 N  N   . TYR A 1 240 ? 5.422   -22.793 -11.396 1   55.68  ? 236 TYR A N   1 
ATOM   1908 C  CA  . TYR A 1 240 ? 5.734   -24.068 -12.013 1   52.78  ? 236 TYR A CA  1 
ATOM   1909 C  C   . TYR A 1 240 ? 7.006   -23.861 -12.825 1   53.85  ? 236 TYR A C   1 
ATOM   1910 O  O   . TYR A 1 240 ? 7.123   -22.888 -13.562 1   57.89  ? 236 TYR A O   1 
ATOM   1911 C  CB  . TYR A 1 240 ? 4.613   -24.573 -12.933 1   58.96  ? 236 TYR A CB  1 
ATOM   1912 C  CG  . TYR A 1 240 ? 4.978   -25.911 -13.564 1   63.63  ? 236 TYR A CG  1 
ATOM   1913 C  CD1 . TYR A 1 240 ? 4.679   -27.105 -12.919 1   71.16  ? 236 TYR A CD1 1 
ATOM   1914 C  CD2 . TYR A 1 240 ? 5.649   -25.986 -14.776 1   65.97  ? 236 TYR A CD2 1 
ATOM   1915 C  CE1 . TYR A 1 240 ? 5.034   -28.332 -13.457 1   73.05  ? 236 TYR A CE1 1 
ATOM   1916 C  CE2 . TYR A 1 240 ? 6.019   -27.207 -15.323 1   72.7   ? 236 TYR A CE2 1 
ATOM   1917 C  CZ  . TYR A 1 240 ? 5.728   -28.384 -14.652 1   78.16  ? 236 TYR A CZ  1 
ATOM   1918 O  OH  . TYR A 1 240 ? 6.086   -29.604 -15.162 1   86.64  ? 236 TYR A OH  1 
ATOM   1919 N  N   . LYS A 1 241 ? 7.917   -24.822 -12.728 1   53.67  ? 237 LYS A N   1 
ATOM   1920 C  CA  . LYS A 1 241 ? 9.132   -24.824 -13.526 1   55.6   ? 237 LYS A CA  1 
ATOM   1921 C  C   . LYS A 1 241 ? 9.203   -26.157 -14.278 1   53.11  ? 237 LYS A C   1 
ATOM   1922 O  O   . LYS A 1 241 ? 8.957   -27.211 -13.69  1   50.56  ? 237 LYS A O   1 
ATOM   1923 C  CB  . LYS A 1 241 ? 10.347  -24.72  -12.592 1   59.15  ? 237 LYS A CB  1 
ATOM   1924 C  CG  . LYS A 1 241 ? 10.457  -23.48  -11.72  1   67.68  ? 237 LYS A CG  1 
ATOM   1925 C  CD  . LYS A 1 241 ? 10.624  -22.224 -12.574 1   78.21  ? 237 LYS A CD  1 
ATOM   1926 C  CE  . LYS A 1 241 ? 10.815  -20.929 -11.807 1   87.21  ? 237 LYS A CE  1 
ATOM   1927 N  NZ  . LYS A 1 241 ? 10.953  -19.711 -12.631 1   89.62  ? 237 LYS A NZ  1 
ATOM   1928 N  N   . PRO A 1 242 ? 9.491   -26.156 -15.604 1   54.63  ? 238 PRO A N   1 
ATOM   1929 C  CA  . PRO A 1 242 ? 9.661   -27.402 -16.363 1   55.8   ? 238 PRO A CA  1 
ATOM   1930 C  C   . PRO A 1 242 ? 10.753  -28.347 -15.854 1   54.31  ? 238 PRO A C   1 
ATOM   1931 O  O   . PRO A 1 242 ? 10.653  -29.553 -16.059 1   53.43  ? 238 PRO A O   1 
ATOM   1932 C  CB  . PRO A 1 242 ? 9.892   -26.984 -17.844 1   52.4   ? 238 PRO A CB  1 
ATOM   1933 C  CG  . PRO A 1 242 ? 10.063  -25.474 -17.816 1   51.44  ? 238 PRO A CG  1 
ATOM   1934 C  CD  . PRO A 1 242 ? 9.662   -24.958 -16.439 1   53.49  ? 238 PRO A CD  1 
ATOM   1935 N  N   . SER A 1 243 ? 11.781  -27.777 -15.202 1   56.36  ? 239 SER A N   1 
ATOM   1936 C  CA  . SER A 1 243 ? 12.909  -28.476 -14.591 1   54.78  ? 239 SER A CA  1 
ATOM   1937 C  C   . SER A 1 243 ? 12.502  -29.339 -13.38  1   50.42  ? 239 SER A C   1 
ATOM   1938 O  O   . SER A 1 243 ? 13.322  -30.13  -12.914 1   45.9   ? 239 SER A O   1 
ATOM   1939 C  CB  . SER A 1 243 ? 13.999  -27.488 -14.203 1   55.79  ? 239 SER A CB  1 
ATOM   1940 O  OG  . SER A 1 243 ? 13.539  -26.625 -13.169 1   56.48  ? 239 SER A OG  1 
ATOM   1941 N  N   . PHE A 1 244 ? 11.26   -29.188 -12.873 1   45.37  ? 240 PHE A N   1 
ATOM   1942 C  CA  . PHE A 1 244 ? 10.754  -30.005 -11.777 1   45.17  ? 240 PHE A CA  1 
ATOM   1943 C  C   . PHE A 1 244 ? 11.009  -31.485 -12.026 1   46.02  ? 240 PHE A C   1 
ATOM   1944 O  O   . PHE A 1 244 ? 10.701  -32.01  -13.093 1   51.51  ? 240 PHE A O   1 
ATOM   1945 C  CB  . PHE A 1 244 ? 9.252   -29.847 -11.576 1   43.04  ? 240 PHE A CB  1 
ATOM   1946 C  CG  . PHE A 1 244 ? 8.823   -28.609 -10.804 1   47.65  ? 240 PHE A CG  1 
ATOM   1947 C  CD1 . PHE A 1 244 ? 9.742   -27.86  -10.078 1   49.34  ? 240 PHE A CD1 1 
ATOM   1948 C  CD2 . PHE A 1 244 ? 7.481   -28.238 -10.761 1   47.02  ? 240 PHE A CD2 1 
ATOM   1949 C  CE1 . PHE A 1 244 ? 9.33    -26.734 -9.379  1   51.18  ? 240 PHE A CE1 1 
ATOM   1950 C  CE2 . PHE A 1 244 ? 7.073   -27.126 -10.044 1   46.41  ? 240 PHE A CE2 1 
ATOM   1951 C  CZ  . PHE A 1 244 ? 7.998   -26.38  -9.352  1   47.42  ? 240 PHE A CZ  1 
ATOM   1952 N  N   . PRO A 1 245 ? 11.602  -32.224 -11.073 1   46.21  ? 241 PRO A N   1 
ATOM   1953 C  CA  . PRO A 1 245 ? 11.773  -33.669 -11.253 1   47.34  ? 241 PRO A CA  1 
ATOM   1954 C  C   . PRO A 1 245 ? 10.411  -34.325 -11.425 1   45.22  ? 241 PRO A C   1 
ATOM   1955 O  O   . PRO A 1 245 ? 9.412   -33.865 -10.885 1   44.11  ? 241 PRO A O   1 
ATOM   1956 C  CB  . PRO A 1 245 ? 12.51   -34.11  -9.984  1   47.66  ? 241 PRO A CB  1 
ATOM   1957 C  CG  . PRO A 1 245 ? 13.226  -32.836 -9.558  1   50.74  ? 241 PRO A CG  1 
ATOM   1958 C  CD  . PRO A 1 245 ? 12.189  -31.729 -9.822  1   48.3   ? 241 PRO A CD  1 
ATOM   1959 N  N   . LYS A 1 246 ? 10.378  -35.379 -12.233 1   50.41  ? 242 LYS A N   1 
ATOM   1960 C  CA  . LYS A 1 246 ? 9.114   -36.032 -12.549 1   56.8   ? 242 LYS A CA  1 
ATOM   1961 C  C   . LYS A 1 246 ? 9.023   -37.353 -11.78  1   51.84  ? 242 LYS A C   1 
ATOM   1962 O  O   . LYS A 1 246 ? 9.445   -38.385 -12.273 1   59.63  ? 242 LYS A O   1 
ATOM   1963 C  CB  . LYS A 1 246 ? 8.894   -36.11  -14.072 1   56.45  ? 242 LYS A CB  1 
ATOM   1964 C  CG  . LYS A 1 246 ? 8.686   -34.764 -14.754 1   65.87  ? 242 LYS A CG  1 
ATOM   1965 C  CD  . LYS A 1 246 ? 8.488   -34.797 -16.269 1   84.78  ? 242 LYS A CD  1 
ATOM   1966 C  CE  . LYS A 1 246 ? 8.267   -33.445 -16.866 1   80.97  ? 242 LYS A CE  1 
ATOM   1967 N  NZ  . LYS A 1 246 ? 8.127   -33.689 -18.299 1   85.61  ? 242 LYS A NZ  1 
ATOM   1968 N  N   . TRP A 1 247 ? 8.486   -37.299 -10.56  1   43.15  ? 243 TRP A N   1 
ATOM   1969 C  CA  . TRP A 1 247 ? 8.391   -38.472 -9.713  1   43.92  ? 243 TRP A CA  1 
ATOM   1970 C  C   . TRP A 1 247 ? 7.12    -39.237 -10.05  1   43.93  ? 243 TRP A C   1 
ATOM   1971 O  O   . TRP A 1 247 ? 6.111   -38.608 -10.335 1   43.83  ? 243 TRP A O   1 
ATOM   1972 C  CB  . TRP A 1 247 ? 8.372   -38.053 -8.239  1   41.06  ? 243 TRP A CB  1 
ATOM   1973 C  CG  . TRP A 1 247 ? 9.724   -37.66  -7.72   1   43.28  ? 243 TRP A CG  1 
ATOM   1974 C  CD1 . TRP A 1 247 ? 10.767  -38.491 -7.434  1   45.82  ? 243 TRP A CD1 1 
ATOM   1975 C  CD2 . TRP A 1 247 ? 10.17   -36.327 -7.389  1   44.48  ? 243 TRP A CD2 1 
ATOM   1976 N  NE1 . TRP A 1 247 ? 11.837  -37.773 -6.96   1   46.11  ? 243 TRP A NE1 1 
ATOM   1977 C  CE2 . TRP A 1 247 ? 11.499  -36.445 -6.915  1   46.46  ? 243 TRP A CE2 1 
ATOM   1978 C  CE3 . TRP A 1 247 ? 9.588   -35.052 -7.461  1   41.89  ? 243 TRP A CE3 1 
ATOM   1979 C  CZ2 . TRP A 1 247 ? 12.236  -35.332 -6.505  1   46.53  ? 243 TRP A CZ2 1 
ATOM   1980 C  CZ3 . TRP A 1 247 ? 10.316  -33.955 -7.043  1   42.71  ? 243 TRP A CZ3 1 
ATOM   1981 C  CH2 . TRP A 1 247 ? 11.622  -34.096 -6.568  1   44.23  ? 243 TRP A CH2 1 
ATOM   1982 N  N   . ALA A 1 248 ? 7.169   -40.575 -9.96   1   46.28  ? 244 ALA A N   1 
ATOM   1983 C  CA  . ALA A 1 248 ? 5.99    -41.417 -10.162 1   47.21  ? 244 ALA A CA  1 
ATOM   1984 C  C   . ALA A 1 248 ? 5.064   -41.356 -8.952  1   47.22  ? 244 ALA A C   1 
ATOM   1985 O  O   . ALA A 1 248 ? 5.518   -41.213 -7.814  1   45.8   ? 244 ALA A O   1 
ATOM   1986 C  CB  . ALA A 1 248 ? 6.393   -42.843 -10.461 1   45.82  ? 244 ALA A CB  1 
ATOM   1987 N  N   . ARG A 1 249 ? 3.754   -41.422 -9.223  1   53.98  ? 245 ARG A N   1 
ATOM   1988 C  CA  . ARG A 1 249 ? 2.748   -41.44  -8.171  1   52.8   ? 245 ARG A CA  1 
ATOM   1989 C  C   . ARG A 1 249 ? 2.913   -42.762 -7.432  1   59.99  ? 245 ARG A C   1 
ATOM   1990 O  O   . ARG A 1 249 ? 3.017   -43.807 -8.062  1   59.13  ? 245 ARG A O   1 
ATOM   1991 C  CB  . ARG A 1 249 ? 1.354   -41.333 -8.79   1   50.71  ? 245 ARG A CB  1 
ATOM   1992 C  CG  . ARG A 1 249 ? 0.272   -41.487 -7.733  1   56.57  ? 245 ARG A CG  1 
ATOM   1993 C  CD  . ARG A 1 249 ? -1.117  -41.174 -8.252  1   57.46  ? 245 ARG A CD  1 
ATOM   1994 N  NE  . ARG A 1 249 ? -2.104  -41.211 -7.165  1   60.61  ? 245 ARG A NE  1 
ATOM   1995 C  CZ  . ARG A 1 249 ? -2.6    -40.156 -6.513  1   61.8   ? 245 ARG A CZ  1 
ATOM   1996 N  NH1 . ARG A 1 249 ? -2.043  -38.955 -6.63   1   55.67  ? 245 ARG A NH1 1 
ATOM   1997 N  NH2 . ARG A 1 249 ? -3.624  -40.325 -5.686  1   60.5   ? 245 ARG A NH2 1 
ATOM   1998 N  N   . GLN A 1 250 ? 3.055   -42.732 -6.109  1   70.66  ? 246 GLN A N   1 
ATOM   1999 C  CA  . GLN A 1 250 ? 3.199   -44.018 -5.444  1   72.01  ? 246 GLN A CA  1 
ATOM   2000 C  C   . GLN A 1 250 ? 1.778   -44.472 -5.117  1   74.01  ? 246 GLN A C   1 
ATOM   2001 O  O   . GLN A 1 250 ? 0.911   -43.616 -4.901  1   63.82  ? 246 GLN A O   1 
ATOM   2002 C  CB  . GLN A 1 250 ? 4.246   -44.013 -4.325  1   67.47  ? 246 GLN A CB  1 
ATOM   2003 C  CG  . GLN A 1 250 ? 3.736   -43.438 -3.011  1   68.63  ? 246 GLN A CG  1 
ATOM   2004 C  CD  . GLN A 1 250 ? 4.835   -43.366 -1.974  1   83.33  ? 246 GLN A CD  1 
ATOM   2005 O  OE1 . GLN A 1 250 ? 5.369   -42.284 -1.724  1   95.33  ? 246 GLN A OE1 1 
ATOM   2006 N  NE2 . GLN A 1 250 ? 5.23    -44.499 -1.397  1   87.59  ? 246 GLN A NE2 1 
ATOM   2007 N  N   . ASP A 1 251 ? 1.556   -45.799 -5.178  1   70.58  ? 247 ASP A N   1 
ATOM   2008 C  CA  . ASP A 1 251 ? 0.291   -46.417 -4.803  1   69.58  ? 247 ASP A CA  1 
ATOM   2009 C  C   . ASP A 1 251 ? -0.067  -45.939 -3.393  1   65.75  ? 247 ASP A C   1 
ATOM   2010 O  O   . ASP A 1 251 ? 0.788   -45.903 -2.513  1   74.33  ? 247 ASP A O   1 
ATOM   2011 C  CB  . ASP A 1 251 ? 0.315   -47.918 -5.097  1   81.17  ? 247 ASP A CB  1 
ATOM   2012 C  CG  . ASP A 1 251 ? -0.968  -48.711 -4.851  1   101.1  ? 247 ASP A CG  1 
ATOM   2013 O  OD1 . ASP A 1 251 ? -1.982  -48.095 -4.44   1   102.52 ? 247 ASP A OD1 1 
ATOM   2014 O  OD2 . ASP A 1 251 ? -0.959  -49.947 -5.095  1   118.92 ? 247 ASP A OD2 1 
ATOM   2015 N  N   . PHE A 1 252 ? -1.343  -45.607 -3.184  1   57.99  ? 248 PHE A N   1 
ATOM   2016 C  CA  . PHE A 1 252 ? -1.828  -44.875 -2.031  1   52.65  ? 248 PHE A CA  1 
ATOM   2017 C  C   . PHE A 1 252 ? -1.829  -45.711 -0.753  1   52.25  ? 248 PHE A C   1 
ATOM   2018 O  O   . PHE A 1 252 ? -1.986  -45.159 0.335   1   62.63  ? 248 PHE A O   1 
ATOM   2019 C  CB  . PHE A 1 252 ? -3.223  -44.349 -2.395  1   54.98  ? 248 PHE A CB  1 
ATOM   2020 C  CG  . PHE A 1 252 ? -3.403  -42.929 -1.878  1   53.04  ? 248 PHE A CG  1 
ATOM   2021 C  CD1 . PHE A 1 252 ? -2.975  -41.847 -2.638  1   55.01  ? 248 PHE A CD1 1 
ATOM   2022 C  CD2 . PHE A 1 252 ? -3.915  -42.676 -0.626  1   51.1   ? 248 PHE A CD2 1 
ATOM   2023 C  CE1 . PHE A 1 252 ? -3.088  -40.543 -2.194  1   44.66  ? 248 PHE A CE1 1 
ATOM   2024 C  CE2 . PHE A 1 252 ? -4.018  -41.364 -0.186  1   50.73  ? 248 PHE A CE2 1 
ATOM   2025 C  CZ  . PHE A 1 252 ? -3.603  -40.305 -0.97   1   43.71  ? 248 PHE A CZ  1 
ATOM   2026 N  N   . SER A 1 253 ? -1.751  -47.038 -0.891  1   50.01  ? 249 SER A N   1 
ATOM   2027 C  CA  . SER A 1 253 ? -1.726  -47.964 0.234   1   49.74  ? 249 SER A CA  1 
ATOM   2028 C  C   . SER A 1 253 ? -0.342  -47.974 0.896   1   52.35  ? 249 SER A C   1 
ATOM   2029 O  O   . SER A 1 253 ? -0.126  -48.609 1.939   1   52.46  ? 249 SER A O   1 
ATOM   2030 C  CB  . SER A 1 253 ? -2.1    -49.353 -0.224  1   48.8   ? 249 SER A CB  1 
ATOM   2031 O  OG  . SER A 1 253 ? -1.047  -49.906 -1.007  1   52.02  ? 249 SER A OG  1 
ATOM   2032 N  N   . LYS A 1 254 ? 0.605   -47.281 0.253   1   53.36  ? 250 LYS A N   1 
ATOM   2033 C  CA  . LYS A 1 254 ? 1.976   -47.189 0.728   1   55.49  ? 250 LYS A CA  1 
ATOM   2034 C  C   . LYS A 1 254 ? 2.16    -45.845 1.421   1   55.03  ? 250 LYS A C   1 
ATOM   2035 O  O   . LYS A 1 254 ? 3.07    -45.705 2.225   1   65.11  ? 250 LYS A O   1 
ATOM   2036 C  CB  . LYS A 1 254 ? 2.969   -47.408 -0.417  1   53.93  ? 250 LYS A CB  1 
ATOM   2037 C  CG  . LYS A 1 254 ? 2.903   -48.828 -0.974  1   55.42  ? 250 LYS A CG  1 
ATOM   2038 C  CD  . LYS A 1 254 ? 3.358   -49.964 -0.056  1   61.04  ? 250 LYS A CD  1 
ATOM   2039 C  CE  . LYS A 1 254 ? 3.284   -51.366 -0.65   1   64.61  ? 250 LYS A CE  1 
ATOM   2040 N  NZ  . LYS A 1 254 ? 1.947   -51.969 -0.535  1   64.93  ? 250 LYS A NZ  1 
ATOM   2041 N  N   . VAL A 1 255 ? 1.257   -44.896 1.145   1   48.64  ? 251 VAL A N   1 
ATOM   2042 C  CA  . VAL A 1 255 ? 1.309   -43.594 1.774   1   48.3   ? 251 VAL A CA  1 
ATOM   2043 C  C   . VAL A 1 255 ? 0.853   -43.693 3.229   1   53.74  ? 251 VAL A C   1 
ATOM   2044 O  O   . VAL A 1 255 ? 1.472   -43.08  4.096   1   59.21  ? 251 VAL A O   1 
ATOM   2045 C  CB  . VAL A 1 255 ? 0.462   -42.579 1.004   1   46.11  ? 251 VAL A CB  1 
ATOM   2046 C  CG1 . VAL A 1 255 ? 0.452   -41.232 1.713   1   48.31  ? 251 VAL A CG1 1 
ATOM   2047 C  CG2 . VAL A 1 255 ? 0.953   -42.462 -0.425  1   44.22  ? 251 VAL A CG2 1 
ATOM   2048 N  N   . VAL A 1 256 ? -0.234  -44.439 3.485   1   53.31  ? 252 VAL A N   1 
ATOM   2049 C  CA  . VAL A 1 256 ? -0.767  -44.595 4.827   1   47.14  ? 252 VAL A CA  1 
ATOM   2050 C  C   . VAL A 1 256 ? -1.163  -46.051 4.994   1   47.86  ? 252 VAL A C   1 
ATOM   2051 O  O   . VAL A 1 256 ? -2.341  -46.379 5.042   1   49.11  ? 252 VAL A O   1 
ATOM   2052 C  CB  . VAL A 1 256 ? -1.931  -43.641 5.147   1   46.25  ? 252 VAL A CB  1 
ATOM   2053 C  CG1 . VAL A 1 256 ? -2.338  -43.733 6.61    1   45.95  ? 252 VAL A CG1 1 
ATOM   2054 C  CG2 . VAL A 1 256 ? -1.564  -42.194 4.846   1   48.54  ? 252 VAL A CG2 1 
ATOM   2055 N  N   . PRO A 1 257 ? -0.173  -46.957 5.119   1   49.05  ? 253 PRO A N   1 
ATOM   2056 C  CA  . PRO A 1 257 ? -0.433  -48.401 5.159   1   49.54  ? 253 PRO A CA  1 
ATOM   2057 C  C   . PRO A 1 257 ? -1.574  -48.876 6.052   1   50.07  ? 253 PRO A C   1 
ATOM   2058 O  O   . PRO A 1 257 ? -2.331  -49.74  5.645   1   54.62  ? 253 PRO A O   1 
ATOM   2059 C  CB  . PRO A 1 257 ? 0.918   -49.01  5.583   1   48.71  ? 253 PRO A CB  1 
ATOM   2060 C  CG  . PRO A 1 257 ? 1.925   -47.992 5.095   1   49.15  ? 253 PRO A CG  1 
ATOM   2061 C  CD  . PRO A 1 257 ? 1.258   -46.625 5.236   1   45.69  ? 253 PRO A CD  1 
ATOM   2062 N  N   . PRO A 1 258 ? -1.737  -48.395 7.303   1   51.39  ? 254 PRO A N   1 
ATOM   2063 C  CA  . PRO A 1 258 ? -2.794  -48.919 8.165   1   54.64  ? 254 PRO A CA  1 
ATOM   2064 C  C   . PRO A 1 258 ? -4.209  -48.613 7.684   1   57.93  ? 254 PRO A C   1 
ATOM   2065 O  O   . PRO A 1 258 ? -5.155  -49.228 8.152   1   74.46  ? 254 PRO A O   1 
ATOM   2066 C  CB  . PRO A 1 258 ? -2.548  -48.307 9.541   1   52.89  ? 254 PRO A CB  1 
ATOM   2067 C  CG  . PRO A 1 258 ? -1.213  -47.612 9.426   1   52.95  ? 254 PRO A CG  1 
ATOM   2068 C  CD  . PRO A 1 258 ? -0.95   -47.345 7.96    1   50.19  ? 254 PRO A CD  1 
ATOM   2069 N  N   . LEU A 1 259 ? -4.353  -47.671 6.751   1   55.47  ? 255 LEU A N   1 
ATOM   2070 C  CA  . LEU A 1 259 ? -5.663  -47.206 6.31    1   50.34  ? 255 LEU A CA  1 
ATOM   2071 C  C   . LEU A 1 259 ? -6.31   -48.238 5.387   1   53     ? 255 LEU A C   1 
ATOM   2072 O  O   . LEU A 1 259 ? -5.63   -48.823 4.544   1   54.7   ? 255 LEU A O   1 
ATOM   2073 C  CB  . LEU A 1 259 ? -5.424  -45.891 5.579   1   46.71  ? 255 LEU A CB  1 
ATOM   2074 C  CG  . LEU A 1 259 ? -6.542  -44.862 5.671   1   45.7   ? 255 LEU A CG  1 
ATOM   2075 C  CD1 . LEU A 1 259 ? -7.069  -44.673 7.089   1   46.97  ? 255 LEU A CD1 1 
ATOM   2076 C  CD2 . LEU A 1 259 ? -6.025  -43.565 5.103   1   40.22  ? 255 LEU A CD2 1 
ATOM   2077 N  N   . ASP A 1 260 ? -7.618  -48.456 5.604   1   57.31  ? 256 ASP A N   1 
ATOM   2078 C  CA  . ASP A 1 260 ? -8.54   -49.326 4.867   1   58.93  ? 256 ASP A CA  1 
ATOM   2079 C  C   . ASP A 1 260 ? -8.901  -48.71  3.503   1   53.9   ? 256 ASP A C   1 
ATOM   2080 O  O   . ASP A 1 260 ? -8.616  -47.546 3.237   1   50.27  ? 256 ASP A O   1 
ATOM   2081 C  CB  . ASP A 1 260 ? -9.79   -49.557 5.717   1   67.52  ? 256 ASP A CB  1 
ATOM   2082 C  CG  . ASP A 1 260 ? -10.557 -48.292 6.145   1   84.41  ? 256 ASP A CG  1 
ATOM   2083 O  OD1 . ASP A 1 260 ? -11.38  -47.789 5.336   1   87.98  ? 256 ASP A OD1 1 
ATOM   2084 O  OD2 . ASP A 1 260 ? -10.316 -47.76  7.271   1   78.9   ? 256 ASP A OD2 1 
ATOM   2085 N  N   . GLU A 1 261 ? -9.627  -49.453 2.662   1   52.87  ? 257 GLU A N   1 
ATOM   2086 C  CA  . GLU A 1 261 ? -9.968  -48.981 1.325   1   54.55  ? 257 GLU A CA  1 
ATOM   2087 C  C   . GLU A 1 261 ? -10.793 -47.678 1.301   1   55.98  ? 257 GLU A C   1 
ATOM   2088 O  O   . GLU A 1 261 ? -10.563 -46.81  0.446   1   52.45  ? 257 GLU A O   1 
ATOM   2089 C  CB  . GLU A 1 261 ? -10.739 -50.121 0.679   1   59.82  ? 257 GLU A CB  1 
ATOM   2090 C  CG  . GLU A 1 261 ? -10.996 -49.944 -0.817  1   70.71  ? 257 GLU A CG  1 
ATOM   2091 C  CD  . GLU A 1 261 ? -11.9   -51.046 -1.367  1   83.74  ? 257 GLU A CD  1 
ATOM   2092 O  OE1 . GLU A 1 261 ? -11.491 -51.668 -2.383  1   97.49  ? 257 GLU A OE1 1 
ATOM   2093 O  OE2 . GLU A 1 261 ? -12.999 -51.285 -0.786  1   78.74  ? 257 GLU A OE2 1 
ATOM   2094 N  N   . ASP A 1 262 ? -11.782 -47.555 2.205   1   50.47  ? 258 ASP A N   1 
ATOM   2095 C  CA  . ASP A 1 262 ? -12.652 -46.397 2.295   1   48.77  ? 258 ASP A CA  1 
ATOM   2096 C  C   . ASP A 1 262 ? -11.824 -45.195 2.73    1   49.21  ? 258 ASP A C   1 
ATOM   2097 O  O   . ASP A 1 262 ? -11.857 -44.136 2.093   1   43.93  ? 258 ASP A O   1 
ATOM   2098 C  CB  . ASP A 1 262 ? -13.788 -46.636 3.278   1   53.91  ? 258 ASP A CB  1 
ATOM   2099 C  CG  . ASP A 1 262 ? -14.944 -47.506 2.792   1   59.38  ? 258 ASP A CG  1 
ATOM   2100 O  OD1 . ASP A 1 262 ? -15.095 -47.657 1.564   1   58.12  ? 258 ASP A OD1 1 
ATOM   2101 O  OD2 . ASP A 1 262 ? -15.675 -48.049 3.656   1   62.17  ? 258 ASP A OD2 1 
ATOM   2102 N  N   . GLY A 1 263 ? -11.082 -45.369 3.83    1   47.41  ? 259 GLY A N   1 
ATOM   2103 C  CA  . GLY A 1 263 ? -10.123 -44.361 4.243   1   46.32  ? 259 GLY A CA  1 
ATOM   2104 C  C   . GLY A 1 263 ? -9.292  -43.852 3.068   1   43.78  ? 259 GLY A C   1 
ATOM   2105 O  O   . GLY A 1 263 ? -9.27   -42.647 2.789   1   42.63  ? 259 GLY A O   1 
ATOM   2106 N  N   . ARG A 1 264 ? -8.645  -44.79  2.365   1   41.26  ? 260 ARG A N   1 
ATOM   2107 C  CA  . ARG A 1 264 ? -7.721  -44.429 1.294   1   45.19  ? 260 ARG A CA  1 
ATOM   2108 C  C   . ARG A 1 264 ? -8.442  -43.588 0.241   1   43.41  ? 260 ARG A C   1 
ATOM   2109 O  O   . ARG A 1 264 ? -7.916  -42.598 -0.24   1   43.45  ? 260 ARG A O   1 
ATOM   2110 C  CB  . ARG A 1 264 ? -7.036  -45.638 0.641   1   46.2   ? 260 ARG A CB  1 
ATOM   2111 C  CG  . ARG A 1 264 ? -6.048  -46.315 1.582   1   51.6   ? 260 ARG A CG  1 
ATOM   2112 C  CD  . ARG A 1 264 ? -5.058  -47.202 0.86    1   55.31  ? 260 ARG A CD  1 
ATOM   2113 N  NE  . ARG A 1 264 ? -5.73   -48.17  -0.01   1   56.04  ? 260 ARG A NE  1 
ATOM   2114 C  CZ  . ARG A 1 264 ? -6.189  -49.351 0.404   1   56.39  ? 260 ARG A CZ  1 
ATOM   2115 N  NH1 . ARG A 1 264 ? -5.94   -49.806 1.627   1   52.22  ? 260 ARG A NH1 1 
ATOM   2116 N  NH2 . ARG A 1 264 ? -6.908  -50.076 -0.43   1   55.05  ? 260 ARG A NH2 1 
ATOM   2117 N  N   . SER A 1 265 ? -9.643  -44.026 -0.13   1   43.08  ? 261 SER A N   1 
ATOM   2118 C  CA  . SER A 1 265 ? -10.474 -43.316 -1.076  1   42.46  ? 261 SER A CA  1 
ATOM   2119 C  C   . SER A 1 265 ? -10.688 -41.868 -0.611  1   43.36  ? 261 SER A C   1 
ATOM   2120 O  O   . SER A 1 265 ? -10.538 -40.929 -1.399  1   38.81  ? 261 SER A O   1 
ATOM   2121 C  CB  . SER A 1 265 ? -11.787 -44.077 -1.233  1   42.21  ? 261 SER A CB  1 
ATOM   2122 O  OG  . SER A 1 265 ? -12.684 -43.422 -2.122  1   50.06  ? 261 SER A OG  1 
ATOM   2123 N  N   . LEU A 1 266 ? -11.097 -41.702 0.658   1   38.59  ? 262 LEU A N   1 
ATOM   2124 C  CA  . LEU A 1 266 ? -11.484 -40.389 1.113   1   41     ? 262 LEU A CA  1 
ATOM   2125 C  C   . LEU A 1 266 ? -10.244 -39.5   1.048   1   45.86  ? 262 LEU A C   1 
ATOM   2126 O  O   . LEU A 1 266 ? -10.276 -38.405 0.462   1   44.47  ? 262 LEU A O   1 
ATOM   2127 C  CB  . LEU A 1 266 ? -12.131 -40.455 2.5     1   43.92  ? 262 LEU A CB  1 
ATOM   2128 C  CG  . LEU A 1 266 ? -12.353 -39.107 3.214   1   44.61  ? 262 LEU A CG  1 
ATOM   2129 C  CD1 . LEU A 1 266 ? -13.086 -38.101 2.326   1   37.56  ? 262 LEU A CD1 1 
ATOM   2130 C  CD2 . LEU A 1 266 ? -13.139 -39.328 4.509   1   44.15  ? 262 LEU A CD2 1 
ATOM   2131 N  N   . LEU A 1 267 ? -9.139  -40.034 1.591   1   45.21  ? 263 LEU A N   1 
ATOM   2132 C  CA  . LEU A 1 267 ? -7.862  -39.343 1.617   1   45.11  ? 263 LEU A CA  1 
ATOM   2133 C  C   . LEU A 1 267 ? -7.429  -38.909 0.216   1   46.12  ? 263 LEU A C   1 
ATOM   2134 O  O   . LEU A 1 267 ? -7.094  -37.736 0.034   1   51.4   ? 263 LEU A O   1 
ATOM   2135 C  CB  . LEU A 1 267 ? -6.794  -40.176 2.311   1   42.27  ? 263 LEU A CB  1 
ATOM   2136 C  CG  . LEU A 1 267 ? -5.465  -39.457 2.508   1   41.27  ? 263 LEU A CG  1 
ATOM   2137 C  CD1 . LEU A 1 267 ? -5.658  -38.225 3.381   1   41.2   ? 263 LEU A CD1 1 
ATOM   2138 C  CD2 . LEU A 1 267 ? -4.477  -40.421 3.087   1   43.24  ? 263 LEU A CD2 1 
ATOM   2139 N  N   . SER A 1 268 ? -7.45   -39.84  -0.75   1   39.21  ? 264 SER A N   1 
ATOM   2140 C  CA  . SER A 1 268 ? -7.098  -39.51  -2.128  1   44.27  ? 264 SER A CA  1 
ATOM   2141 C  C   . SER A 1 268 ? -7.935  -38.351 -2.678  1   42.01  ? 264 SER A C   1 
ATOM   2142 O  O   . SER A 1 268 ? -7.423  -37.528 -3.43   1   44.63  ? 264 SER A O   1 
ATOM   2143 C  CB  . SER A 1 268 ? -7.128  -40.701 -3.059  1   44.16  ? 264 SER A CB  1 
ATOM   2144 O  OG  . SER A 1 268 ? -8.455  -41.187 -3.192  1   51.94  ? 264 SER A OG  1 
ATOM   2145 N  N   . GLN A 1 269 ? -9.203  -38.268 -2.282  1   37.19  ? 265 GLN A N   1 
ATOM   2146 C  CA  . GLN A 1 269 ? -10.075 -37.26  -2.848  1   42.4   ? 265 GLN A CA  1 
ATOM   2147 C  C   . GLN A 1 269 ? -9.844  -35.912 -2.158  1   42.74  ? 265 GLN A C   1 
ATOM   2148 O  O   . GLN A 1 269 ? -10.151 -34.876 -2.736  1   39.86  ? 265 GLN A O   1 
ATOM   2149 C  CB  . GLN A 1 269 ? -11.524 -37.741 -2.808  1   41.37  ? 265 GLN A CB  1 
ATOM   2150 C  CG  . GLN A 1 269 ? -11.78  -38.967 -3.683  1   45.02  ? 265 GLN A CG  1 
ATOM   2151 C  CD  . GLN A 1 269 ? -13.169 -39.543 -3.477  1   50.84  ? 265 GLN A CD  1 
ATOM   2152 O  OE1 . GLN A 1 269 ? -13.359 -40.672 -3.003  1   54.49  ? 265 GLN A OE1 1 
ATOM   2153 N  NE2 . GLN A 1 269 ? -14.171 -38.721 -3.75   1   51.03  ? 265 GLN A NE2 1 
ATOM   2154 N  N   . MET A 1 270 ? -9.278  -35.93  -0.941  1   40.74  ? 266 MET A N   1 
ATOM   2155 C  CA  . MET A 1 270 ? -8.91   -34.703 -0.25   1   41.93  ? 266 MET A CA  1 
ATOM   2156 C  C   . MET A 1 270 ? -7.582  -34.149 -0.785  1   50.44  ? 266 MET A C   1 
ATOM   2157 O  O   . MET A 1 270 ? -7.386  -32.926 -0.791  1   50.98  ? 266 MET A O   1 
ATOM   2158 C  CB  . MET A 1 270 ? -8.878  -34.905 1.267   1   39.21  ? 266 MET A CB  1 
ATOM   2159 C  CG  . MET A 1 270 ? -10.232 -35.312 1.815   1   39.45  ? 266 MET A CG  1 
ATOM   2160 S  SD  . MET A 1 270 ? -10.327 -35.707 3.579   1   47.36  ? 266 MET A SD  1 
ATOM   2161 C  CE  . MET A 1 270 ? -10.444 -34.052 4.281   1   34.03  ? 266 MET A CE  1 
ATOM   2162 N  N   . LEU A 1 271 ? -6.703  -35.043 -1.281  1   46.23  ? 267 LEU A N   1 
ATOM   2163 C  CA  . LEU A 1 271 ? -5.365  -34.691 -1.743  1   46.17  ? 267 LEU A CA  1 
ATOM   2164 C  C   . LEU A 1 271 ? -5.253  -34.705 -3.272  1   46.02  ? 267 LEU A C   1 
ATOM   2165 O  O   . LEU A 1 271 ? -4.169  -34.83  -3.838  1   46.14  ? 267 LEU A O   1 
ATOM   2166 C  CB  . LEU A 1 271 ? -4.347  -35.628 -1.087  1   45.73  ? 267 LEU A CB  1 
ATOM   2167 C  CG  . LEU A 1 271 ? -4.337  -35.662 0.444   1   44.13  ? 267 LEU A CG  1 
ATOM   2168 C  CD1 . LEU A 1 271 ? -3.284  -36.635 0.93    1   44.66  ? 267 LEU A CD1 1 
ATOM   2169 C  CD2 . LEU A 1 271 ? -4.1    -34.275 1.03    1   38.79  ? 267 LEU A CD2 1 
ATOM   2170 N  N   . HIS A 1 272 ? -6.37   -34.507 -3.957  1   47.17  ? 268 HIS A N   1 
ATOM   2171 C  CA  . HIS A 1 272 ? -6.365  -34.41  -5.406  1   50     ? 268 HIS A CA  1 
ATOM   2172 C  C   . HIS A 1 272 ? -5.619  -33.136 -5.785  1   47.38  ? 268 HIS A C   1 
ATOM   2173 O  O   . HIS A 1 272 ? -5.814  -32.099 -5.147  1   42.89  ? 268 HIS A O   1 
ATOM   2174 C  CB  . HIS A 1 272 ? -7.809  -34.416 -5.923  1   54.31  ? 268 HIS A CB  1 
ATOM   2175 C  CG  . HIS A 1 272 ? -8.002  -34.965 -7.298  1   70.51  ? 268 HIS A CG  1 
ATOM   2176 N  ND1 . HIS A 1 272 ? -7.611  -34.277 -8.437  1   81.64  ? 268 HIS A ND1 1 
ATOM   2177 C  CD2 . HIS A 1 272 ? -8.544  -36.125 -7.709  1   67.53  ? 268 HIS A CD2 1 
ATOM   2178 C  CE1 . HIS A 1 272 ? -7.928  -34.987 -9.513  1   77.53  ? 268 HIS A CE1 1 
ATOM   2179 N  NE2 . HIS A 1 272 ? -8.506  -36.105 -9.092  1   82.62  ? 268 HIS A NE2 1 
ATOM   2180 N  N   . TYR A 1 273 ? -4.781  -33.227 -6.824  1   46.85  ? 269 TYR A N   1 
ATOM   2181 C  CA  . TYR A 1 273 ? -3.983  -32.091 -7.243  1   48.62  ? 269 TYR A CA  1 
ATOM   2182 C  C   . TYR A 1 273 ? -4.909  -30.967 -7.684  1   47.86  ? 269 TYR A C   1 
ATOM   2183 O  O   . TYR A 1 273 ? -4.759  -29.82  -7.252  1   54.21  ? 269 TYR A O   1 
ATOM   2184 C  CB  . TYR A 1 273 ? -2.951  -32.44  -8.318  1   43.93  ? 269 TYR A CB  1 
ATOM   2185 C  CG  . TYR A 1 273 ? -1.623  -32.93  -7.767  1   43.62  ? 269 TYR A CG  1 
ATOM   2186 C  CD1 . TYR A 1 273 ? -0.763  -32.056 -7.114  1   45.47  ? 269 TYR A CD1 1 
ATOM   2187 C  CD2 . TYR A 1 273 ? -1.231  -34.259 -7.891  1   43.63  ? 269 TYR A CD2 1 
ATOM   2188 C  CE1 . TYR A 1 273 ? 0.462   -32.482 -6.622  1   41.5   ? 269 TYR A CE1 1 
ATOM   2189 C  CE2 . TYR A 1 273 ? -0.015  -34.697 -7.391  1   42.03  ? 269 TYR A CE2 1 
ATOM   2190 C  CZ  . TYR A 1 273 ? 0.84    -33.803 -6.763  1   43.35  ? 269 TYR A CZ  1 
ATOM   2191 O  OH  . TYR A 1 273 ? 2.047   -34.214 -6.248  1   47.6   ? 269 TYR A OH  1 
ATOM   2192 N  N   . ASP A 1 274 ? -5.868  -31.339 -8.529  1   42.36  ? 270 ASP A N   1 
ATOM   2193 C  CA  . ASP A 1 274 ? -6.713  -30.382 -9.214  1   44.8   ? 270 ASP A CA  1 
ATOM   2194 C  C   . ASP A 1 274 ? -7.717  -29.843 -8.207  1   47.5   ? 270 ASP A C   1 
ATOM   2195 O  O   . ASP A 1 274 ? -8.566  -30.598 -7.74   1   55.14  ? 270 ASP A O   1 
ATOM   2196 C  CB  . ASP A 1 274 ? -7.386  -31.041 -10.414 1   43.8   ? 270 ASP A CB  1 
ATOM   2197 C  CG  . ASP A 1 274 ? -8.149  -30.079 -11.315 1   48.45  ? 270 ASP A CG  1 
ATOM   2198 O  OD1 . ASP A 1 274 ? -8.332  -28.901 -10.899 1   49.6   ? 270 ASP A OD1 1 
ATOM   2199 O  OD2 . ASP A 1 274 ? -8.546  -30.505 -12.429 1   52.89  ? 270 ASP A OD2 1 
ATOM   2200 N  N   . PRO A 1 275 ? -7.685  -28.55  -7.811  1   51.52  ? 271 PRO A N   1 
ATOM   2201 C  CA  . PRO A 1 275 ? -8.599  -28.066 -6.772  1   45.83  ? 271 PRO A CA  1 
ATOM   2202 C  C   . PRO A 1 275 ? -10.045 -28.262 -7.225  1   46.6   ? 271 PRO A C   1 
ATOM   2203 O  O   . PRO A 1 275 ? -10.922 -28.467 -6.386  1   46.86  ? 271 PRO A O   1 
ATOM   2204 C  CB  . PRO A 1 275 ? -8.229  -26.577 -6.557  1   43.13  ? 271 PRO A CB  1 
ATOM   2205 C  CG  . PRO A 1 275 ? -6.886  -26.422 -7.189  1   41.37  ? 271 PRO A CG  1 
ATOM   2206 C  CD  . PRO A 1 275 ? -6.802  -27.487 -8.307  1   49.87  ? 271 PRO A CD  1 
ATOM   2207 N  N   . ASN A 1 276 ? -10.273 -28.249 -8.55   1   46.51  ? 272 ASN A N   1 
ATOM   2208 C  CA  . ASN A 1 276 ? -11.61  -28.462 -9.1    1   48.72  ? 272 ASN A CA  1 
ATOM   2209 C  C   . ASN A 1 276 ? -12.129 -29.89  -8.863  1   46.86  ? 272 ASN A C   1 
ATOM   2210 O  O   . ASN A 1 276 ? -13.325 -30.062 -8.77   1   47.13  ? 272 ASN A O   1 
ATOM   2211 C  CB  . ASN A 1 276 ? -11.707 -28.13  -10.582 1   45.33  ? 272 ASN A CB  1 
ATOM   2212 C  CG  . ASN A 1 276 ? -11.467 -26.673 -10.88  1   49.54  ? 272 ASN A CG  1 
ATOM   2213 O  OD1 . ASN A 1 276 ? -11.879 -25.804 -10.116 1   57.65  ? 272 ASN A OD1 1 
ATOM   2214 N  ND2 . ASN A 1 276 ? -10.812 -26.375 -11.989 1   58.52  ? 272 ASN A ND2 1 
ATOM   2215 N  N   . LYS A 1 277 ? -11.266 -30.913 -8.773  1   46.94  ? 273 LYS A N   1 
ATOM   2216 C  CA  . LYS A 1 277 ? -11.711 -32.286 -8.553  1   49.57  ? 273 LYS A CA  1 
ATOM   2217 C  C   . LYS A 1 277 ? -11.646 -32.628 -7.068  1   46.32  ? 273 LYS A C   1 
ATOM   2218 O  O   . LYS A 1 277 ? -12.171 -33.643 -6.633  1   43.97  ? 273 LYS A O   1 
ATOM   2219 C  CB  . LYS A 1 277 ? -10.823 -33.308 -9.276  1   57.94  ? 273 LYS A CB  1 
ATOM   2220 C  CG  . LYS A 1 277 ? -10.65  -33.11  -10.784 1   71.5   ? 273 LYS A CG  1 
ATOM   2221 C  CD  . LYS A 1 277 ? -11.994 -32.902 -11.477 1   83.88  ? 273 LYS A CD  1 
ATOM   2222 C  CE  . LYS A 1 277 ? -11.932 -32.91  -12.981 1   96.19  ? 273 LYS A CE  1 
ATOM   2223 N  NZ  . LYS A 1 277 ? -13.104 -32.245 -13.564 1   98.59  ? 273 LYS A NZ  1 
ATOM   2224 N  N   . ARG A 1 278 ? -10.965 -31.791 -6.281  1   44.4   ? 274 ARG A N   1 
ATOM   2225 C  CA  . ARG A 1 278 ? -10.794 -32.122 -4.877  1   41.14  ? 274 ARG A CA  1 
ATOM   2226 C  C   . ARG A 1 278 ? -12.169 -32.129 -4.214  1   40.67  ? 274 ARG A C   1 
ATOM   2227 O  O   . ARG A 1 278 ? -13.013 -31.29  -4.527  1   42.27  ? 274 ARG A O   1 
ATOM   2228 C  CB  . ARG A 1 278 ? -9.799  -31.124 -4.295  1   38.46  ? 274 ARG A CB  1 
ATOM   2229 C  CG  . ARG A 1 278 ? -9.119  -31.604 -3.027  1   43.24  ? 274 ARG A CG  1 
ATOM   2230 C  CD  . ARG A 1 278 ? -8.162  -30.524 -2.533  1   45.36  ? 274 ARG A CD  1 
ATOM   2231 N  NE  . ARG A 1 278 ? -7.107  -30.211 -3.5    1   43.65  ? 274 ARG A NE  1 
ATOM   2232 C  CZ  . ARG A 1 278 ? -6.436  -29.055 -3.521  1   40.43  ? 274 ARG A CZ  1 
ATOM   2233 N  NH1 . ARG A 1 278 ? -6.679  -28.128 -2.611  1   33.91  ? 274 ARG A NH1 1 
ATOM   2234 N  NH2 . ARG A 1 278 ? -5.531  -28.846 -4.463  1   35.22  ? 274 ARG A NH2 1 
ATOM   2235 N  N   . ILE A 1 279 ? -12.399 -33.083 -3.307  1   37.06  ? 275 ILE A N   1 
ATOM   2236 C  CA  . ILE A 1 279 ? -13.728 -33.255 -2.735  1   37.25  ? 275 ILE A CA  1 
ATOM   2237 C  C   . ILE A 1 279 ? -14.074 -32.061 -1.844  1   36.86  ? 275 ILE A C   1 
ATOM   2238 O  O   . ILE A 1 279 ? -13.194 -31.523 -1.196  1   40.72  ? 275 ILE A O   1 
ATOM   2239 C  CB  . ILE A 1 279 ? -13.785 -34.589 -1.972  1   35.96  ? 275 ILE A CB  1 
ATOM   2240 C  CG1 . ILE A 1 279 ? -15.206 -34.956 -1.564  1   32.39  ? 275 ILE A CG1 1 
ATOM   2241 C  CG2 . ILE A 1 279 ? -12.849 -34.55  -0.767  1   36.93  ? 275 ILE A CG2 1 
ATOM   2242 C  CD1 . ILE A 1 279 ? -15.359 -36.396 -1.161  1   32.87  ? 275 ILE A CD1 1 
ATOM   2243 N  N   . SER A 1 280 ? -15.356 -31.684 -1.764  1   39.69  ? 276 SER A N   1 
ATOM   2244 C  CA  . SER A 1 280 ? -15.796 -30.633 -0.842  1   43.66  ? 276 SER A CA  1 
ATOM   2245 C  C   . SER A 1 280 ? -16.12  -31.208 0.538   1   46.54  ? 276 SER A C   1 
ATOM   2246 O  O   . SER A 1 280 ? -16.404 -32.402 0.651   1   41.19  ? 276 SER A O   1 
ATOM   2247 C  CB  . SER A 1 280 ? -17.009 -29.912 -1.373  1   40.59  ? 276 SER A CB  1 
ATOM   2248 O  OG  . SER A 1 280 ? -18.12  -30.793 -1.35   1   41.04  ? 276 SER A OG  1 
ATOM   2249 N  N   . ALA A 1 281 ? -16.144 -30.346 1.571   1   46.56  ? 277 ALA A N   1 
ATOM   2250 C  CA  . ALA A 1 281 ? -16.527 -30.799 2.902   1   45.54  ? 277 ALA A CA  1 
ATOM   2251 C  C   . ALA A 1 281 ? -17.932 -31.408 2.879   1   44.23  ? 277 ALA A C   1 
ATOM   2252 O  O   . ALA A 1 281 ? -18.197 -32.46  3.464   1   47.98  ? 277 ALA A O   1 
ATOM   2253 C  CB  . ALA A 1 281 ? -16.456 -29.65  3.872   1   46.09  ? 277 ALA A CB  1 
ATOM   2254 N  N   . LYS A 1 282 ? -18.841 -30.716 2.201   1   44.33  ? 278 LYS A N   1 
ATOM   2255 C  CA  . LYS A 1 282 ? -20.231 -31.126 2.087   1   45.31  ? 278 LYS A CA  1 
ATOM   2256 C  C   . LYS A 1 282 ? -20.341 -32.534 1.48    1   44.69  ? 278 LYS A C   1 
ATOM   2257 O  O   . LYS A 1 282 ? -20.901 -33.435 2.092   1   46.7   ? 278 LYS A O   1 
ATOM   2258 C  CB  . LYS A 1 282 ? -20.903 -29.957 1.362   1   44.51  ? 278 LYS A CB  1 
ATOM   2259 C  CG  . LYS A 1 282 ? -22.354 -30.086 1.034   1   46.53  ? 278 LYS A CG  1 
ATOM   2260 C  CD  . LYS A 1 282 ? -22.816 -28.826 0.311   1   54.86  ? 278 LYS A CD  1 
ATOM   2261 C  CE  . LYS A 1 282 ? -23.065 -27.661 1.226   1   57.23  ? 278 LYS A CE  1 
ATOM   2262 N  NZ  . LYS A 1 282 ? -23.985 -26.721 0.575   1   49.97  ? 278 LYS A NZ  1 
ATOM   2263 N  N   . ALA A 1 283 ? -19.726 -32.774 0.321   1   51.69  ? 279 ALA A N   1 
ATOM   2264 C  CA  . ALA A 1 283 ? -19.711 -34.109 -0.297  1   52     ? 279 ALA A CA  1 
ATOM   2265 C  C   . ALA A 1 283 ? -19.018 -35.184 0.557   1   46.84  ? 279 ALA A C   1 
ATOM   2266 O  O   . ALA A 1 283 ? -19.435 -36.349 0.542   1   51.81  ? 279 ALA A O   1 
ATOM   2267 C  CB  . ALA A 1 283 ? -19.129 -34.069 -1.701  1   38.18  ? 279 ALA A CB  1 
ATOM   2268 N  N   . ALA A 1 284 ? -17.955 -34.801 1.277   1   42.51  ? 280 ALA A N   1 
ATOM   2269 C  CA  . ALA A 1 284 ? -17.141 -35.754 2.011   1   39.43  ? 280 ALA A CA  1 
ATOM   2270 C  C   . ALA A 1 284 ? -17.935 -36.343 3.167   1   41.86  ? 280 ALA A C   1 
ATOM   2271 O  O   . ALA A 1 284 ? -17.703 -37.491 3.525   1   47.99  ? 280 ALA A O   1 
ATOM   2272 C  CB  . ALA A 1 284 ? -15.866 -35.118 2.477   1   36.11  ? 280 ALA A CB  1 
ATOM   2273 N  N   . LEU A 1 285 ? -18.881 -35.577 3.723   1   38.95  ? 281 LEU A N   1 
ATOM   2274 C  CA  . LEU A 1 285 ? -19.689 -36.069 4.831   1   40.71  ? 281 LEU A CA  1 
ATOM   2275 C  C   . LEU A 1 285 ? -20.449 -37.339 4.452   1   47.61  ? 281 LEU A C   1 
ATOM   2276 O  O   . LEU A 1 285 ? -20.869 -38.081 5.352   1   48.94  ? 281 LEU A O   1 
ATOM   2277 C  CB  . LEU A 1 285 ? -20.685 -35.003 5.287   1   44.7   ? 281 LEU A CB  1 
ATOM   2278 C  CG  . LEU A 1 285 ? -20.106 -33.813 6.06    1   42.87  ? 281 LEU A CG  1 
ATOM   2279 C  CD1 . LEU A 1 285 ? -21.191 -32.79  6.309   1   41.3   ? 281 LEU A CD1 1 
ATOM   2280 C  CD2 . LEU A 1 285 ? -19.53  -34.294 7.362   1   38.03  ? 281 LEU A CD2 1 
ATOM   2281 N  N   . ALA A 1 286 ? -20.673 -37.559 3.141   1   42.15  ? 282 ALA A N   1 
ATOM   2282 C  CA  . ALA A 1 286 ? -21.433 -38.724 2.696   1   43.31  ? 282 ALA A CA  1 
ATOM   2283 C  C   . ALA A 1 286 ? -20.542 -39.922 2.375   1   45.17  ? 282 ALA A C   1 
ATOM   2284 O  O   . ALA A 1 286 ? -21.06  -41     2.05    1   50.92  ? 282 ALA A O   1 
ATOM   2285 C  CB  . ALA A 1 286 ? -22.244 -38.394 1.478   1   43.79  ? 282 ALA A CB  1 
ATOM   2286 N  N   . HIS A 1 287 ? -19.216 -39.724 2.423   1   43.1   ? 283 HIS A N   1 
ATOM   2287 C  CA  . HIS A 1 287 ? -18.293 -40.769 2.012   1   40.63  ? 283 HIS A CA  1 
ATOM   2288 C  C   . HIS A 1 287 ? -18.51  -42.031 2.84    1   43.25  ? 283 HIS A C   1 
ATOM   2289 O  O   . HIS A 1 287 ? -18.757 -41.963 4.041   1   48.99  ? 283 HIS A O   1 
ATOM   2290 C  CB  . HIS A 1 287 ? -16.854 -40.28  2.099   1   37.97  ? 283 HIS A CB  1 
ATOM   2291 C  CG  . HIS A 1 287 ? -15.897 -41.201 1.418   1   46.4   ? 283 HIS A CG  1 
ATOM   2292 N  ND1 . HIS A 1 287 ? -15.539 -42.433 1.942   1   45.82  ? 283 HIS A ND1 1 
ATOM   2293 C  CD2 . HIS A 1 287 ? -15.222 -41.066 0.245   1   45.65  ? 283 HIS A CD2 1 
ATOM   2294 C  CE1 . HIS A 1 287 ? -14.683 -43.016 1.109   1   52.3   ? 283 HIS A CE1 1 
ATOM   2295 N  NE2 . HIS A 1 287 ? -14.481 -42.213 0.061   1   46.93  ? 283 HIS A NE2 1 
ATOM   2296 N  N   . PRO A 1 288 ? -18.461 -43.222 2.214   1   43.64  ? 284 PRO A N   1 
ATOM   2297 C  CA  . PRO A 1 288 ? -18.599 -44.49  2.946   1   45.93  ? 284 PRO A CA  1 
ATOM   2298 C  C   . PRO A 1 288 ? -17.7   -44.686 4.17    1   45.16  ? 284 PRO A C   1 
ATOM   2299 O  O   . PRO A 1 288 ? -18.033 -45.481 5.052   1   48.41  ? 284 PRO A O   1 
ATOM   2300 C  CB  . PRO A 1 288 ? -18.343 -45.6   1.91    1   42.59  ? 284 PRO A CB  1 
ATOM   2301 C  CG  . PRO A 1 288 ? -18.416 -44.9   0.564   1   43.11  ? 284 PRO A CG  1 
ATOM   2302 C  CD  . PRO A 1 288 ? -18.281 -43.399 0.766   1   40.31  ? 284 PRO A CD  1 
ATOM   2303 N  N   . PHE A 1 289 ? -16.567 -43.972 4.234   1   43.23  ? 285 PHE A N   1 
ATOM   2304 C  CA  . PHE A 1 289 ? -15.685 -44.08  5.384   1   41.81  ? 285 PHE A CA  1 
ATOM   2305 C  C   . PHE A 1 289 ? -16.451 -43.781 6.682   1   47.87  ? 285 PHE A C   1 
ATOM   2306 O  O   . PHE A 1 289 ? -16.159 -44.357 7.739   1   52.74  ? 285 PHE A O   1 
ATOM   2307 C  CB  . PHE A 1 289 ? -14.472 -43.182 5.15    1   42.65  ? 285 PHE A CB  1 
ATOM   2308 C  CG  . PHE A 1 289 ? -13.448 -43.159 6.275   1   46.54  ? 285 PHE A CG  1 
ATOM   2309 C  CD1 . PHE A 1 289 ? -12.603 -44.254 6.506   1   45.98  ? 285 PHE A CD1 1 
ATOM   2310 C  CD2 . PHE A 1 289 ? -13.346 -42.04  7.109   1   46.71  ? 285 PHE A CD2 1 
ATOM   2311 C  CE1 . PHE A 1 289 ? -11.672 -44.249 7.534   1   41.72  ? 285 PHE A CE1 1 
ATOM   2312 C  CE2 . PHE A 1 289 ? -12.417 -42.045 8.149   1   47.61  ? 285 PHE A CE2 1 
ATOM   2313 C  CZ  . PHE A 1 289 ? -11.589 -43.149 8.359   1   44.13  ? 285 PHE A CZ  1 
ATOM   2314 N  N   . PHE A 1 290 ? -17.479 -42.923 6.605   1   44.43  ? 286 PHE A N   1 
ATOM   2315 C  CA  . PHE A 1 290 ? -18.203 -42.517 7.797   1   45.5   ? 286 PHE A CA  1 
ATOM   2316 C  C   . PHE A 1 290 ? -19.402 -43.413 8.135   1   54.99  ? 286 PHE A C   1 
ATOM   2317 O  O   . PHE A 1 290 ? -20.115 -43.085 9.091   1   57.89  ? 286 PHE A O   1 
ATOM   2318 C  CB  . PHE A 1 290 ? -18.603 -41.041 7.689   1   41.45  ? 286 PHE A CB  1 
ATOM   2319 C  CG  . PHE A 1 290 ? -17.403 -40.121 7.566   1   40.1   ? 286 PHE A CG  1 
ATOM   2320 C  CD1 . PHE A 1 290 ? -16.471 -40.036 8.591   1   41.57  ? 286 PHE A CD1 1 
ATOM   2321 C  CD2 . PHE A 1 290 ? -17.197 -39.365 6.413   1   41.79  ? 286 PHE A CD2 1 
ATOM   2322 C  CE1 . PHE A 1 290 ? -15.371 -39.201 8.455   1   43.64  ? 286 PHE A CE1 1 
ATOM   2323 C  CE2 . PHE A 1 290 ? -16.103 -38.526 6.286   1   39.11  ? 286 PHE A CE2 1 
ATOM   2324 C  CZ  . PHE A 1 290 ? -15.189 -38.448 7.31    1   40.68  ? 286 PHE A CZ  1 
ATOM   2325 N  N   . GLN A 1 291 ? -19.606 -44.541 7.421   1   56.58  ? 287 GLN A N   1 
ATOM   2326 C  CA  . GLN A 1 291 ? -20.844 -45.313 7.489   1   66.86  ? 287 GLN A CA  1 
ATOM   2327 C  C   . GLN A 1 291 ? -21.228 -45.695 8.929   1   74.79  ? 287 GLN A C   1 
ATOM   2328 O  O   . GLN A 1 291 ? -22.415 -45.801 9.26    1   85.02  ? 287 GLN A O   1 
ATOM   2329 C  CB  . GLN A 1 291 ? -20.844 -46.512 6.536   1   73.55  ? 287 GLN A CB  1 
ATOM   2330 C  CG  . GLN A 1 291 ? -19.858 -47.628 6.872   1   92.31  ? 287 GLN A CG  1 
ATOM   2331 C  CD  . GLN A 1 291 ? -19.934 -48.809 5.916   1   112.64 ? 287 GLN A CD  1 
ATOM   2332 O  OE1 . GLN A 1 291 ? -20.891 -49.596 5.939   1   122.34 ? 287 GLN A OE1 1 
ATOM   2333 N  NE2 . GLN A 1 291 ? -18.934 -48.947 5.053   1   99.79  ? 287 GLN A NE2 1 
ATOM   2334 N  N   . ASP A 1 292 ? -20.234 -45.884 9.803   1   70.65  ? 288 ASP A N   1 
ATOM   2335 C  CA  . ASP A 1 292 ? -20.478 -46.377 11.156  1   74.53  ? 288 ASP A CA  1 
ATOM   2336 C  C   . ASP A 1 292 ? -20.034 -45.35  12.21   1   73.27  ? 288 ASP A C   1 
ATOM   2337 O  O   . ASP A 1 292 ? -19.774 -45.74  13.354  1   65.27  ? 288 ASP A O   1 
ATOM   2338 C  CB  . ASP A 1 292 ? -19.747 -47.699 11.345  1   80.95  ? 288 ASP A CB  1 
ATOM   2339 C  CG  . ASP A 1 292 ? -18.295 -47.639 10.871  1   87.6   ? 288 ASP A CG  1 
ATOM   2340 O  OD1 . ASP A 1 292 ? -17.919 -46.659 10.141  1   80.83  ? 288 ASP A OD1 1 
ATOM   2341 O  OD2 . ASP A 1 292 ? -17.535 -48.546 11.246  1   84.27  ? 288 ASP A OD2 1 
ATOM   2342 N  N   . VAL A 1 293 ? -19.983 -44.048 11.847  1   72.85  ? 289 VAL A N   1 
ATOM   2343 C  CA  . VAL A 1 293 ? -19.435 -42.986 12.688  1   68.6   ? 289 VAL A CA  1 
ATOM   2344 C  C   . VAL A 1 293 ? -20.275 -42.816 13.962  1   80.72  ? 289 VAL A C   1 
ATOM   2345 O  O   . VAL A 1 293 ? -21.505 -42.946 13.944  1   70.9   ? 289 VAL A O   1 
ATOM   2346 C  CB  . VAL A 1 293 ? -19.23  -41.654 11.937  1   65.05  ? 289 VAL A CB  1 
ATOM   2347 C  CG1 . VAL A 1 293 ? -20.548 -40.957 11.592  1   73.89  ? 289 VAL A CG1 1 
ATOM   2348 C  CG2 . VAL A 1 293 ? -18.336 -40.676 12.691  1   61.62  ? 289 VAL A CG2 1 
ATOM   2349 N  N   . THR A 1 294 ? -19.541 -42.595 15.058  1   91.06  ? 290 THR A N   1 
ATOM   2350 C  CA  . THR A 1 294 ? -20.147 -42.353 16.374  1   99.73  ? 290 THR A CA  1 
ATOM   2351 C  C   . THR A 1 294 ? -19.452 -41.134 16.928  1   101.75 ? 290 THR A C   1 
ATOM   2352 O  O   . THR A 1 294 ? -18.668 -40.531 16.181  1   112.09 ? 290 THR A O   1 
ATOM   2353 C  CB  . THR A 1 294 ? -19.905 -43.558 17.276  1   99.61  ? 290 THR A CB  1 
ATOM   2354 O  OG1 . THR A 1 294 ? -18.597 -44.025 16.961  1   90.3   ? 290 THR A OG1 1 
ATOM   2355 C  CG2 . THR A 1 294 ? -20.93  -44.656 17.058  1   99.42  ? 290 THR A CG2 1 
ATOM   2356 N  N   . LYS A 1 295 ? -19.708 -40.767 18.181  1   97.5   ? 291 LYS A N   1 
ATOM   2357 C  CA  . LYS A 1 295 ? -18.955 -39.645 18.795  1   101.92 ? 291 LYS A CA  1 
ATOM   2358 C  C   . LYS A 1 295 ? -18.321 -40.13  20.105  1   112.68 ? 291 LYS A C   1 
ATOM   2359 O  O   . LYS A 1 295 ? -18.83  -39.767 21.185  1   110.02 ? 291 LYS A O   1 
ATOM   2360 C  CB  . LYS A 1 295 ? -19.83  -38.421 19.077  1   101.48 ? 291 LYS A CB  1 
ATOM   2361 C  CG  . LYS A 1 295 ? -19.075 -37.141 19.407  1   99.25  ? 291 LYS A CG  1 
ATOM   2362 C  CD  . LYS A 1 295 ? -19.935 -36.177 20.213  1   114.74 ? 291 LYS A CD  1 
ATOM   2363 C  CE  . LYS A 1 295 ? -19.142 -35.101 20.876  1   135.18 ? 291 LYS A CE  1 
ATOM   2364 N  NZ  . LYS A 1 295 ? -19.708 -34.715 22.17   1   126.41 ? 291 LYS A NZ  1 
ATOM   2365 N  N   . PRO A 1 296 ? -17.243 -40.941 20.058  1   106.56 ? 292 PRO A N   1 
ATOM   2366 C  CA  . PRO A 1 296 ? -16.581 -41.37  21.275  1   97.73  ? 292 PRO A CA  1 
ATOM   2367 C  C   . PRO A 1 296 ? -15.778 -40.249 21.924  1   91.54  ? 292 PRO A C   1 
ATOM   2368 O  O   . PRO A 1 296 ? -15.281 -39.357 21.245  1   77.33  ? 292 PRO A O   1 
ATOM   2369 C  CB  . PRO A 1 296 ? -15.713 -42.519 20.756  1   93.95  ? 292 PRO A CB  1 
ATOM   2370 C  CG  . PRO A 1 296 ? -15.386 -42.141 19.338  1   92.05  ? 292 PRO A CG  1 
ATOM   2371 C  CD  . PRO A 1 296 ? -16.655 -41.488 18.849  1   103.67 ? 292 PRO A CD  1 
ATOM   2372 N  N   . VAL A 1 297 ? -15.645 -40.296 23.245  1   94.75  ? 293 VAL A N   1 
ATOM   2373 C  CA  . VAL A 1 297 ? -14.906 -39.235 23.985  1   95.59  ? 293 VAL A CA  1 
ATOM   2374 C  C   . VAL A 1 297 ? -13.421 -39.592 24.016  1   88.21  ? 293 VAL A C   1 
ATOM   2375 O  O   . VAL A 1 297 ? -13.102 -40.769 23.791  1   97.18  ? 293 VAL A O   1 
ATOM   2376 C  CB  . VAL A 1 297 ? -15.479 -39.142 25.412  1   93.62  ? 293 VAL A CB  1 
ATOM   2377 C  CG1 . VAL A 1 297 ? -17     -39.112 25.406  1   93.09  ? 293 VAL A CG1 1 
ATOM   2378 C  CG2 . VAL A 1 297 ? -14.987 -40.271 26.308  1   83.33  ? 293 VAL A CG2 1 
ATOM   2379 N  N   . PRO A 1 298 ? -12.489 -38.641 24.23   1   93.66  ? 294 PRO A N   1 
ATOM   2380 C  CA  . PRO A 1 298 ? -11.092 -39.003 24.419  1   94.51  ? 294 PRO A CA  1 
ATOM   2381 C  C   . PRO A 1 298 ? -11.086 -39.452 25.886  1   98.36  ? 294 PRO A C   1 
ATOM   2382 O  O   . PRO A 1 298 ? -11.963 -39.048 26.684  1   82.88  ? 294 PRO A O   1 
ATOM   2383 C  CB  . PRO A 1 298 ? -10.347 -37.674 24.146  1   83.73  ? 294 PRO A CB  1 
ATOM   2384 C  CG  . PRO A 1 298 ? -11.301 -36.629 24.676  1   87.14  ? 294 PRO A CG  1 
ATOM   2385 C  CD  . PRO A 1 298 ? -12.699 -37.191 24.374  1   92.36  ? 294 PRO A CD  1 
ATOM   2386 N  N   . GLY B 2 1   ? -15.499 -23.986 -11.908 1   47.05  ? 171 GLY B N   1 
ATOM   2387 C  CA  . GLY B 2 1   ? -14.753 -24.853 -10.977 1   50.69  ? 171 GLY B CA  1 
ATOM   2388 C  C   . GLY B 2 1   ? -14.854 -24.326 -9.537  1   59.23  ? 171 GLY B C   1 
ATOM   2389 O  O   . GLY B 2 1   ? -15.765 -23.552 -9.183  1   55.13  ? 171 GLY B O   1 
ATOM   2390 N  N   . VAL B 2 2   ? -13.861 -24.709 -8.718  1   52.55  ? 172 VAL B N   1 
ATOM   2391 C  CA  . VAL B 2 2   ? -13.904 -24.423 -7.3    1   50.87  ? 172 VAL B CA  1 
ATOM   2392 C  C   . VAL B 2 2   ? -13.857 -22.906 -7.032  1   50.67  ? 172 VAL B C   1 
ATOM   2393 O  O   . VAL B 2 2   ? -14.348 -22.455 -5.988  1   48.78  ? 172 VAL B O   1 
ATOM   2394 C  CB  . VAL B 2 2   ? -12.83  -25.263 -6.592  1   50.36  ? 172 VAL B CB  1 
ATOM   2395 C  CG1 . VAL B 2 2   ? -11.433 -24.687 -6.839  1   49.97  ? 172 VAL B CG1 1 
ATOM   2396 C  CG2 . VAL B 2 2   ? -13.174 -25.475 -5.11   1   45.94  ? 172 VAL B CG2 1 
ATOM   2397 N  N   . ASN B 2 3   ? -13.354 -22.112 -7.997  1   49.94  ? 173 ASN B N   1 
ATOM   2398 C  CA  . ASN B 2 3   ? -13.229 -20.658 -7.837  1   50.12  ? 173 ASN B CA  1 
ATOM   2399 C  C   . ASN B 2 3   ? -14.615 -20.014 -7.812  1   48.55  ? 173 ASN B C   1 
ATOM   2400 O  O   . ASN B 2 3   ? -14.791 -18.962 -7.2    1   44.6   ? 173 ASN B O   1 
ATOM   2401 C  CB  . ASN B 2 3   ? -12.231 -20.015 -8.807  1   49.23  ? 173 ASN B CB  1 
ATOM   2402 C  CG  . ASN B 2 3   ? -10.808 -20.523 -8.654  1   52.55  ? 173 ASN B CG  1 
ATOM   2403 O  OD1 . ASN B 2 3   ? -10.429 -21.052 -7.595  1   54.33  ? 173 ASN B OD1 1 
ATOM   2404 N  ND2 . ASN B 2 3   ? -9.998  -20.358 -9.692  1   49.93  ? 173 ASN B ND2 1 
ATOM   2405 N  N   . GLU B 2 4   ? -15.592 -20.691 -8.439  1   49.87  ? 174 GLU B N   1 
ATOM   2406 C  CA  . GLU B 2 4   ? -16.997 -20.316 -8.39   1   49.59  ? 174 GLU B CA  1 
ATOM   2407 C  C   . GLU B 2 4   ? -17.765 -21.139 -7.346  1   49.32  ? 174 GLU B C   1 
ATOM   2408 O  O   . GLU B 2 4   ? -18.982 -21.082 -7.317  1   48.95  ? 174 GLU B O   1 
ATOM   2409 C  CB  . GLU B 2 4   ? -17.671 -20.602 -9.731  1   53.31  ? 174 GLU B CB  1 
ATOM   2410 C  CG  . GLU B 2 4   ? -16.731 -20.502 -10.928 1   64.56  ? 174 GLU B CG  1 
ATOM   2411 C  CD  . GLU B 2 4   ? -17.375 -20.23  -12.278 1   69.63  ? 174 GLU B CD  1 
ATOM   2412 O  OE1 . GLU B 2 4   ? -18.298 -20.963 -12.713 1   68.4   ? 174 GLU B OE1 1 
ATOM   2413 O  OE2 . GLU B 2 4   ? -16.913 -19.248 -12.901 1   70.04  ? 174 GLU B OE2 1 
ATOM   2414 N  N   . VAL B 2 5   ? -17.066 -21.927 -6.514  1   46.72  ? 175 VAL B N   1 
ATOM   2415 C  CA  . VAL B 2 5   ? -17.603 -22.692 -5.393  1   45.71  ? 175 VAL B CA  1 
ATOM   2416 C  C   . VAL B 2 5   ? -18.958 -23.288 -5.747  1   47.36  ? 175 VAL B C   1 
ATOM   2417 O  O   . VAL B 2 5   ? -19.971 -22.931 -5.133  1   49.12  ? 175 VAL B O   1 
ATOM   2418 C  CB  . VAL B 2 5   ? -17.662 -21.967 -4.027  1   44.5   ? 175 VAL B CB  1 
ATOM   2419 C  CG1 . VAL B 2 5   ? -16.301 -21.932 -3.352  1   45.42  ? 175 VAL B CG1 1 
ATOM   2420 C  CG2 . VAL B 2 5   ? -18.261 -20.57  -4.124  1   39.91  ? 175 VAL B CG2 1 
ATOM   2421 N  N   . PRO B 2 6   ? -18.999 -24.227 -6.718  1   49.83  ? 176 PRO B N   1 
ATOM   2422 C  CA  . PRO B 2 6   ? -20.227 -24.938 -7.078  1   52.11  ? 176 PRO B CA  1 
ATOM   2423 C  C   . PRO B 2 6   ? -21.044 -25.474 -5.898  1   56.26  ? 176 PRO B C   1 
ATOM   2424 O  O   . PRO B 2 6   ? -22.271 -25.387 -5.936  1   61.67  ? 176 PRO B O   1 
ATOM   2425 C  CB  . PRO B 2 6   ? -19.75  -26.086 -8.014  1   48.97  ? 176 PRO B CB  1 
ATOM   2426 C  CG  . PRO B 2 6   ? -18.236 -26.075 -7.934  1   46.36  ? 176 PRO B CG  1 
ATOM   2427 C  CD  . PRO B 2 6   ? -17.847 -24.668 -7.52   1   48.34  ? 176 PRO B CD  1 
ATOM   2428 N  N   . ASP B 2 7   ? -20.364 -26.022 -4.869  1   50.24  ? 177 ASP B N   1 
ATOM   2429 C  CA  . ASP B 2 7   ? -21.026 -26.723 -3.786  1   47.81  ? 177 ASP B CA  1 
ATOM   2430 C  C   . ASP B 2 7   ? -21.572 -25.787 -2.701  1   49.03  ? 177 ASP B C   1 
ATOM   2431 O  O   . ASP B 2 7   ? -22.263 -26.289 -1.805  1   51.11  ? 177 ASP B O   1 
ATOM   2432 C  CB  . ASP B 2 7   ? -20.164 -27.829 -3.199  1   49.36  ? 177 ASP B CB  1 
ATOM   2433 C  CG  . ASP B 2 7   ? -20.174 -29.15  -3.95   1   51.19  ? 177 ASP B CG  1 
ATOM   2434 O  OD1 . ASP B 2 7   ? -20.677 -29.165 -5.091  1   55.43  ? 177 ASP B OD1 1 
ATOM   2435 O  OD2 . ASP B 2 7   ? -19.701 -30.159 -3.381  1   50.27  ? 177 ASP B OD2 1 
ATOM   2436 N  N   . TYR B 2 8   ? -21.312 -24.462 -2.802  1   43.01  ? 178 TYR B N   1 
ATOM   2437 C  CA  . TYR B 2 8   ? -21.643 -23.512 -1.737  1   43.5   ? 178 TYR B CA  1 
ATOM   2438 C  C   . TYR B 2 8   ? -22.274 -22.213 -2.253  1   44.09  ? 178 TYR B C   1 
ATOM   2439 O  O   . TYR B 2 8   ? -22.732 -21.415 -1.429  1   41.83  ? 178 TYR B O   1 
ATOM   2440 C  CB  . TYR B 2 8   ? -20.449 -23.153 -0.825  1   41.91  ? 178 TYR B CB  1 
ATOM   2441 C  CG  . TYR B 2 8   ? -19.787 -24.354 -0.167  1   41.28  ? 178 TYR B CG  1 
ATOM   2442 C  CD1 . TYR B 2 8   ? -20.355 -24.944 0.96    1   43.9   ? 178 TYR B CD1 1 
ATOM   2443 C  CD2 . TYR B 2 8   ? -18.663 -24.957 -0.711  1   37.61  ? 178 TYR B CD2 1 
ATOM   2444 C  CE1 . TYR B 2 8   ? -19.815 -26.076 1.552   1   40.78  ? 178 TYR B CE1 1 
ATOM   2445 C  CE2 . TYR B 2 8   ? -18.127 -26.108 -0.139  1   40.21  ? 178 TYR B CE2 1 
ATOM   2446 C  CZ  . TYR B 2 8   ? -18.681 -26.657 1.011   1   40.76  ? 178 TYR B CZ  1 
ATOM   2447 O  OH  . TYR B 2 8   ? -18.15  -27.779 1.602   1   40.87  ? 178 TYR B OH  1 
ATOM   2448 N  N   . HIS B 2 9   ? -22.326 -21.995 -3.585  1   44.39  ? 179 HIS B N   1 
ATOM   2449 C  CA  . HIS B 2 9   ? -22.799 -20.7   -4.083  1   52.21  ? 179 HIS B CA  1 
ATOM   2450 C  C   . HIS B 2 9   ? -24.237 -20.384 -3.642  1   49.99  ? 179 HIS B C   1 
ATOM   2451 O  O   . HIS B 2 9   ? -24.563 -19.221 -3.424  1   52.21  ? 179 HIS B O   1 
ATOM   2452 C  CB  . HIS B 2 9   ? -22.503 -20.462 -5.581  1   58.49  ? 179 HIS B CB  1 
ATOM   2453 C  CG  . HIS B 2 9   ? -23.437 -21.123 -6.545  1   69.06  ? 179 HIS B CG  1 
ATOM   2454 N  ND1 . HIS B 2 9   ? -23.328 -22.447 -6.945  1   76.67  ? 179 HIS B ND1 1 
ATOM   2455 C  CD2 . HIS B 2 9   ? -24.528 -20.645 -7.147  1   64.6   ? 179 HIS B CD2 1 
ATOM   2456 C  CE1 . HIS B 2 9   ? -24.32  -22.757 -7.771  1   71.72  ? 179 HIS B CE1 1 
ATOM   2457 N  NE2 . HIS B 2 9   ? -25.068 -21.68  -7.894  1   75.05  ? 179 HIS B NE2 1 
ATOM   2458 N  N   . GLU B 2 10  ? -25.108 -21.406 -3.56   1   47.59  ? 180 GLU B N   1 
ATOM   2459 C  CA  . GLU B 2 10  ? -26.504 -21.216 -3.199  1   47.65  ? 180 GLU B CA  1 
ATOM   2460 C  C   . GLU B 2 10  ? -26.638 -20.891 -1.711  1   47.4   ? 180 GLU B C   1 
ATOM   2461 O  O   . GLU B 2 10  ? -27.331 -19.939 -1.348  1   51.61  ? 180 GLU B O   1 
ATOM   2462 C  CB  . GLU B 2 10  ? -27.329 -22.475 -3.411  1   50.31  ? 180 GLU B CB  1 
ATOM   2463 C  CG  . GLU B 2 10  ? -27.86  -22.718 -4.818  1   67.54  ? 180 GLU B CG  1 
ATOM   2464 C  CD  . GLU B 2 10  ? -28.808 -23.918 -4.737  1   85.66  ? 180 GLU B CD  1 
ATOM   2465 O  OE1 . GLU B 2 10  ? -29.705 -23.938 -3.842  1   74.63  ? 180 GLU B OE1 1 
ATOM   2466 O  OE2 . GLU B 2 10  ? -28.639 -24.856 -5.563  1   96.15  ? 180 GLU B OE2 1 
ATOM   2467 N  N   . ASP B 2 11  ? -26.01  -21.722 -0.866  1   42.16  ? 181 ASP B N   1 
ATOM   2468 C  CA  . ASP B 2 11  ? -25.919 -21.476 0.561   1   42.03  ? 181 ASP B CA  1 
ATOM   2469 C  C   . ASP B 2 11  ? -25.429 -20.054 0.79    1   41.73  ? 181 ASP B C   1 
ATOM   2470 O  O   . ASP B 2 11  ? -25.988 -19.341 1.617   1   44.85  ? 181 ASP B O   1 
ATOM   2471 C  CB  . ASP B 2 11  ? -25.021 -22.479 1.269   1   47.09  ? 181 ASP B CB  1 
ATOM   2472 C  CG  . ASP B 2 11  ? -25.541 -23.904 1.458   1   56.2   ? 181 ASP B CG  1 
ATOM   2473 O  OD1 . ASP B 2 11  ? -26.771 -24.133 1.288   1   57.41  ? 181 ASP B OD1 1 
ATOM   2474 O  OD2 . ASP B 2 11  ? -24.708 -24.793 1.79    1   56.6   ? 181 ASP B OD2 1 
ATOM   2475 N  N   . ILE B 2 12  ? -24.393 -19.644 0.054   1   40.97  ? 182 ILE B N   1 
ATOM   2476 C  CA  . ILE B 2 12  ? -23.811 -18.331 0.26    1   41.34  ? 182 ILE B CA  1 
ATOM   2477 C  C   . ILE B 2 12  ? -24.814 -17.258 -0.163  1   43.3   ? 182 ILE B C   1 
ATOM   2478 O  O   . ILE B 2 12  ? -25.045 -16.311 0.576   1   43.03  ? 182 ILE B O   1 
ATOM   2479 C  CB  . ILE B 2 12  ? -22.461 -18.217 -0.468  1   41.53  ? 182 ILE B CB  1 
ATOM   2480 C  CG1 . ILE B 2 12  ? -21.406 -19.092 0.209   1   45.64  ? 182 ILE B CG1 1 
ATOM   2481 C  CG2 . ILE B 2 12  ? -21.99  -16.771 -0.585  1   36.88  ? 182 ILE B CG2 1 
ATOM   2482 C  CD1 . ILE B 2 12  ? -20.151 -19.345 -0.625  1   42.4   ? 182 ILE B CD1 1 
ATOM   2483 N  N   . HIS B 2 13  ? -25.424 -17.406 -1.347  1   46.93  ? 183 HIS B N   1 
ATOM   2484 C  CA  . HIS B 2 13  ? -26.402 -16.429 -1.812  1   44.39  ? 183 HIS B CA  1 
ATOM   2485 C  C   . HIS B 2 13  ? -27.53  -16.266 -0.785  1   46.76  ? 183 HIS B C   1 
ATOM   2486 O  O   . HIS B 2 13  ? -27.868 -15.145 -0.405  1   46.06  ? 183 HIS B O   1 
ATOM   2487 C  CB  . HIS B 2 13  ? -26.966 -16.835 -3.175  1   43.06  ? 183 HIS B CB  1 
ATOM   2488 C  CG  . HIS B 2 13  ? -28.03  -15.913 -3.657  1   45.59  ? 183 HIS B CG  1 
ATOM   2489 N  ND1 . HIS B 2 13  ? -27.738 -14.65  -4.13   1   46.35  ? 183 HIS B ND1 1 
ATOM   2490 C  CD2 . HIS B 2 13  ? -29.356 -16.028 -3.703  1   42.14  ? 183 HIS B CD2 1 
ATOM   2491 C  CE1 . HIS B 2 13  ? -28.852 -14.024 -4.455  1   43.05  ? 183 HIS B CE1 1 
ATOM   2492 N  NE2 . HIS B 2 13  ? -29.839 -14.845 -4.213  1   48.05  ? 183 HIS B NE2 1 
ATOM   2493 N  N   . THR B 2 14  ? -28.102 -17.394 -0.334  1   43.23  ? 184 THR B N   1 
ATOM   2494 C  CA  . THR B 2 14  ? -29.148 -17.403 0.679   1   45.98  ? 184 THR B CA  1 
ATOM   2495 C  C   . THR B 2 14  ? -28.693 -16.665 1.938   1   45.81  ? 184 THR B C   1 
ATOM   2496 O  O   . THR B 2 14  ? -29.399 -15.783 2.417   1   52.14  ? 184 THR B O   1 
ATOM   2497 C  CB  . THR B 2 14  ? -29.57  -18.828 1.028   1   48.13  ? 184 THR B CB  1 
ATOM   2498 O  OG1 . THR B 2 14  ? -30.185 -19.398 -0.127  1   48.42  ? 184 THR B OG1 1 
ATOM   2499 C  CG2 . THR B 2 14  ? -30.466 -18.853 2.26    1   43.88  ? 184 THR B CG2 1 
ATOM   2500 N  N   . TYR B 2 15  ? -27.516 -17.018 2.466   1   45.1   ? 185 TYR B N   1 
ATOM   2501 C  CA  . TYR B 2 15  ? -26.951 -16.344 3.623   1   41.3   ? 185 TYR B CA  1 
ATOM   2502 C  C   . TYR B 2 15  ? -26.797 -14.841 3.373   1   41.16  ? 185 TYR B C   1 
ATOM   2503 O  O   . TYR B 2 15  ? -27.208 -14.045 4.218   1   42.2   ? 185 TYR B O   1 
ATOM   2504 C  CB  . TYR B 2 15  ? -25.665 -17.04  4.047   1   41.45  ? 185 TYR B CB  1 
ATOM   2505 C  CG  . TYR B 2 15  ? -25.026 -16.381 5.258   1   46.15  ? 185 TYR B CG  1 
ATOM   2506 C  CD1 . TYR B 2 15  ? -25.637 -16.434 6.508   1   51.95  ? 185 TYR B CD1 1 
ATOM   2507 C  CD2 . TYR B 2 15  ? -23.817 -15.705 5.146   1   45.25  ? 185 TYR B CD2 1 
ATOM   2508 C  CE1 . TYR B 2 15  ? -25.053 -15.844 7.617   1   52.81  ? 185 TYR B CE1 1 
ATOM   2509 C  CE2 . TYR B 2 15  ? -23.232 -15.09  6.237   1   52     ? 185 TYR B CE2 1 
ATOM   2510 C  CZ  . TYR B 2 15  ? -23.847 -15.175 7.476   1   56.56  ? 185 TYR B CZ  1 
ATOM   2511 O  OH  . TYR B 2 15  ? -23.254 -14.589 8.547   1   53.66  ? 185 TYR B OH  1 
ATOM   2512 N  N   . LEU B 2 16  ? -26.265 -14.426 2.211   1   40.26  ? 186 LEU B N   1 
ATOM   2513 C  CA  . LEU B 2 16  ? -26.083 -13.002 1.96    1   39.43  ? 186 LEU B CA  1 
ATOM   2514 C  C   . LEU B 2 16  ? -27.431 -12.27  1.966   1   45.35  ? 186 LEU B C   1 
ATOM   2515 O  O   . LEU B 2 16  ? -27.52  -11.117 2.429   1   46.79  ? 186 LEU B O   1 
ATOM   2516 C  CB  . LEU B 2 16  ? -25.311 -12.768 0.668   1   36.65  ? 186 LEU B CB  1 
ATOM   2517 C  CG  . LEU B 2 16  ? -23.868 -13.266 0.61    1   37.66  ? 186 LEU B CG  1 
ATOM   2518 C  CD1 . LEU B 2 16  ? -23.297 -13.122 -0.792  1   38.33  ? 186 LEU B CD1 1 
ATOM   2519 C  CD2 . LEU B 2 16  ? -23.008 -12.51  1.575   1   36.64  ? 186 LEU B CD2 1 
ATOM   2520 N  N   . ARG B 2 17  ? -28.476 -12.948 1.456   1   41.71  ? 187 ARG B N   1 
ATOM   2521 C  CA  . ARG B 2 17  ? -29.825 -12.393 1.433   1   47.68  ? 187 ARG B CA  1 
ATOM   2522 C  C   . ARG B 2 17  ? -30.357 -12.117 2.845   1   48.82  ? 187 ARG B C   1 
ATOM   2523 O  O   . ARG B 2 17  ? -30.99  -11.094 3.116   1   51.27  ? 187 ARG B O   1 
ATOM   2524 C  CB  . ARG B 2 17  ? -30.772 -13.3   0.643   1   41.17  ? 187 ARG B CB  1 
ATOM   2525 C  CG  . ARG B 2 17  ? -30.523 -13.189 -0.857  1   41.64  ? 187 ARG B CG  1 
ATOM   2526 C  CD  . ARG B 2 17  ? -31.04  -11.923 -1.534  1   38.66  ? 187 ARG B CD  1 
ATOM   2527 N  NE  . ARG B 2 17  ? -32.487 -11.814 -1.337  1   41.45  ? 187 ARG B NE  1 
ATOM   2528 C  CZ  . ARG B 2 17  ? -33.391 -12.262 -2.195  1   44.67  ? 187 ARG B CZ  1 
ATOM   2529 N  NH1 . ARG B 2 17  ? -33.025 -12.762 -3.37   1   45.04  ? 187 ARG B NH1 1 
ATOM   2530 N  NH2 . ARG B 2 17  ? -34.669 -12.199 -1.872  1   42.04  ? 187 ARG B NH2 1 
ATOM   2531 N  N   . GLU B 2 18  ? -30.07  -13.024 3.767   1   46.12  ? 188 GLU B N   1 
ATOM   2532 C  CA  . GLU B 2 18  ? -30.514 -12.827 5.165   1   50.43  ? 188 GLU B CA  1 
ATOM   2533 C  C   . GLU B 2 18  ? -29.66  -11.728 5.812   1   48.54  ? 188 GLU B C   1 
ATOM   2534 O  O   . GLU B 2 18  ? -30.212 -10.926 6.58    1   48.19  ? 188 GLU B O   1 
ATOM   2535 C  CB  . GLU B 2 18  ? -30.46  -14.18  5.873   1   48.17  ? 188 GLU B CB  1 
ATOM   2536 C  CG  . GLU B 2 18  ? -29.874 -14.128 7.279   1   63.96  ? 188 GLU B CG  1 
ATOM   2537 C  CD  . GLU B 2 18  ? -30     -15.463 7.983   1   83.94  ? 188 GLU B CD  1 
ATOM   2538 O  OE1 . GLU B 2 18  ? -29.88  -16.496 7.293   1   82.51  ? 188 GLU B OE1 1 
ATOM   2539 O  OE2 . GLU B 2 18  ? -30.228 -15.471 9.209   1   79.52  ? 188 GLU B OE2 1 
ATOM   2540 N  N   . MET B 2 19  ? -28.372 -11.683 5.487   1   46.88  ? 189 MET B N   1 
ATOM   2541 C  CA  . MET B 2 19  ? -27.496 -10.713 6.125   1   47.85  ? 189 MET B CA  1 
ATOM   2542 C  C   . MET B 2 19  ? -27.739 -9.293  5.616   1   47.07  ? 189 MET B C   1 
ATOM   2543 O  O   . MET B 2 19  ? -27.583 -8.37   6.396   1   48.33  ? 189 MET B O   1 
ATOM   2544 C  CB  . MET B 2 19  ? -26.019 -11.1   5.977   1   43.65  ? 189 MET B CB  1 
ATOM   2545 C  CG  . MET B 2 19  ? -25.607 -12.282 6.848   1   53.3   ? 189 MET B CG  1 
ATOM   2546 S  SD  . MET B 2 19  ? -26.208 -12.296 8.556   1   60.85  ? 189 MET B SD  1 
ATOM   2547 C  CE  . MET B 2 19  ? -25.049 -11.125 9.279   1   69.04  ? 189 MET B CE  1 
ATOM   2548 N  N   . GLU B 2 20  ? -28.074 -9.109  4.328   1   46.55  ? 190 GLU B N   1 
ATOM   2549 C  CA  . GLU B 2 20  ? -28.239 -7.762  3.795   1   46.38  ? 190 GLU B CA  1 
ATOM   2550 C  C   . GLU B 2 20  ? -29.383 -7.062  4.533   1   48.44  ? 190 GLU B C   1 
ATOM   2551 O  O   . GLU B 2 20  ? -29.327 -5.857  4.777   1   46.57  ? 190 GLU B O   1 
ATOM   2552 C  CB  . GLU B 2 20  ? -28.394 -7.692  2.272   1   43.17  ? 190 GLU B CB  1 
ATOM   2553 C  CG  . GLU B 2 20  ? -29.71  -8.224  1.706   1   46.02  ? 190 GLU B CG  1 
ATOM   2554 C  CD  . GLU B 2 20  ? -29.817 -8.046  0.196   1   47.67  ? 190 GLU B CD  1 
ATOM   2555 O  OE1 . GLU B 2 20  ? -28.992 -7.308  -0.404  1   43.34  ? 190 GLU B OE1 1 
ATOM   2556 O  OE2 . GLU B 2 20  ? -30.718 -8.674  -0.384  1   43.31  ? 190 GLU B OE2 1 
ATOM   2557 N  N   . VAL B 2 21  ? -30.41  -7.843  4.894   1   48.02  ? 191 VAL B N   1 
ATOM   2558 C  CA  . VAL B 2 21  ? -31.508 -7.372  5.721   1   49.49  ? 191 VAL B CA  1 
ATOM   2559 C  C   . VAL B 2 21  ? -31.011 -6.937  7.109   1   51.2   ? 191 VAL B C   1 
ATOM   2560 O  O   . VAL B 2 21  ? -31.442 -5.912  7.604   1   54.43  ? 191 VAL B O   1 
ATOM   2561 C  CB  . VAL B 2 21  ? -32.65  -8.407  5.818   1   46.87  ? 191 VAL B CB  1 
ATOM   2562 C  CG1 . VAL B 2 21  ? -33.748 -7.928  6.754   1   39.16  ? 191 VAL B CG1 1 
ATOM   2563 C  CG2 . VAL B 2 21  ? -33.262 -8.758  4.462   1   41.41  ? 191 VAL B CG2 1 
ATOM   2564 N  N   . LYS B 2 22  ? -30.116 -7.693  7.754   1   59.18  ? 192 LYS B N   1 
ATOM   2565 C  CA  . LYS B 2 22  ? -29.628 -7.335  9.083   1   63.01  ? 192 LYS B CA  1 
ATOM   2566 C  C   . LYS B 2 22  ? -28.739 -6.088  9.027   1   62.84  ? 192 LYS B C   1 
ATOM   2567 O  O   . LYS B 2 22  ? -28.705 -5.317  9.977   1   66.62  ? 192 LYS B O   1 
ATOM   2568 C  CB  . LYS B 2 22  ? -28.834 -8.453  9.771   1   66.38  ? 192 LYS B CB  1 
ATOM   2569 C  CG  . LYS B 2 22  ? -29.605 -9.726  10.09   1   87.86  ? 192 LYS B CG  1 
ATOM   2570 C  CD  . LYS B 2 22  ? -28.961 -10.61  11.16   1   100.22 ? 192 LYS B CD  1 
ATOM   2571 C  CE  . LYS B 2 22  ? -29.057 -12.085 10.845  1   103.08 ? 192 LYS B CE  1 
ATOM   2572 N  NZ  . LYS B 2 22  ? -30.422 -12.611 10.764  1   88.38  ? 192 LYS B NZ  1 
ATOM   2573 N  N   . CYS B 2 23  ? -28.003 -5.905  7.922   1   57.64  ? 193 CYS B N   1 
ATOM   2574 C  CA  . CYS B 2 23  ? -26.976 -4.881  7.788   1   55.75  ? 193 CYS B CA  1 
ATOM   2575 C  C   . CYS B 2 23  ? -27.556 -3.64   7.116   1   57.16  ? 193 CYS B C   1 
ATOM   2576 O  O   . CYS B 2 23  ? -26.81  -2.748  6.694   1   55.58  ? 193 CYS B O   1 
ATOM   2577 C  CB  . CYS B 2 23  ? -25.785 -5.398  6.975   1   54.94  ? 193 CYS B CB  1 
ATOM   2578 S  SG  . CYS B 2 23  ? -24.807 -6.657  7.856   1   72.5   ? 193 CYS B SG  1 
ATOM   2579 N  N   . LYS B 2 24  ? -28.889 -3.6    6.995   1   51.6   ? 194 LYS B N   1 
ATOM   2580 C  CA  . LYS B 2 24  ? -29.535 -2.531  6.253   1   52.75  ? 194 LYS B CA  1 
ATOM   2581 C  C   . LYS B 2 24  ? -29.523 -1.251  7.092   1   54.01  ? 194 LYS B C   1 
ATOM   2582 O  O   . LYS B 2 24  ? -29.86  -1.273  8.272   1   54.82  ? 194 LYS B O   1 
ATOM   2583 C  CB  . LYS B 2 24  ? -30.985 -2.877  5.911   1   52.52  ? 194 LYS B CB  1 
ATOM   2584 C  CG  . LYS B 2 24  ? -31.466 -2.167  4.671   1   54.96  ? 194 LYS B CG  1 
ATOM   2585 C  CD  . LYS B 2 24  ? -32.968 -1.996  4.46    1   57.85  ? 194 LYS B CD  1 
ATOM   2586 C  CE  . LYS B 2 24  ? -33.193 -1.121  3.229   1   60.81  ? 194 LYS B CE  1 
ATOM   2587 N  NZ  . LYS B 2 24  ? -34.547 -1.205  2.673   1   66.56  ? 194 LYS B NZ  1 
ATOM   2588 N  N   . PRO B 2 25  ? -29.132 -0.091  6.519   1   53.75  ? 195 PRO B N   1 
ATOM   2589 C  CA  . PRO B 2 25  ? -29.241 1.18    7.229   1   53.16  ? 195 PRO B CA  1 
ATOM   2590 C  C   . PRO B 2 25  ? -30.711 1.541   7.356   1   51.68  ? 195 PRO B C   1 
ATOM   2591 O  O   . PRO B 2 25  ? -31.556 0.929   6.724   1   58.72  ? 195 PRO B O   1 
ATOM   2592 C  CB  . PRO B 2 25  ? -28.492 2.197   6.337   1   58.39  ? 195 PRO B CB  1 
ATOM   2593 C  CG  . PRO B 2 25  ? -27.723 1.348   5.326   1   52.71  ? 195 PRO B CG  1 
ATOM   2594 C  CD  . PRO B 2 25  ? -28.513 0.057   5.189   1   54.73  ? 195 PRO B CD  1 
ATOM   2595 N  N   . LYS B 2 26  ? -30.994 2.539   8.189   1   52.71  ? 196 LYS B N   1 
ATOM   2596 C  CA  . LYS B 2 26  ? -32.318 3.113   8.324   1   54.35  ? 196 LYS B CA  1 
ATOM   2597 C  C   . LYS B 2 26  ? -32.569 3.959   7.089   1   55.93  ? 196 LYS B C   1 
ATOM   2598 O  O   . LYS B 2 26  ? -31.777 4.837   6.784   1   61.86  ? 196 LYS B O   1 
ATOM   2599 C  CB  . LYS B 2 26  ? -32.432 3.978   9.584   1   58.44  ? 196 LYS B CB  1 
ATOM   2600 C  CG  . LYS B 2 26  ? -33.047 3.328   10.824  1   78.56  ? 196 LYS B CG  1 
ATOM   2601 C  CD  . LYS B 2 26  ? -32.891 4.02    12.185  1   90.38  ? 196 LYS B CD  1 
ATOM   2602 C  CE  . LYS B 2 26  ? -32.608 5.521   12.263  1   97.75  ? 196 LYS B CE  1 
ATOM   2603 N  NZ  . LYS B 2 26  ? -33.614 6.492   11.812  1   92.44  ? 196 LYS B NZ  1 
ATOM   2604 N  N   . VAL B 2 27  ? -33.68  3.697   6.4     1   57.17  ? 197 VAL B N   1 
ATOM   2605 C  CA  . VAL B 2 27  ? -34.033 4.428   5.197   1   56     ? 197 VAL B CA  1 
ATOM   2606 C  C   . VAL B 2 27  ? -34.196 5.914   5.507   1   59.95  ? 197 VAL B C   1 
ATOM   2607 O  O   . VAL B 2 27  ? -33.839 6.766   4.703   1   70.67  ? 197 VAL B O   1 
ATOM   2608 C  CB  . VAL B 2 27  ? -35.29  3.877   4.5     1   56.5   ? 197 VAL B CB  1 
ATOM   2609 C  CG1 . VAL B 2 27  ? -35.556 4.601   3.178   1   52.24  ? 197 VAL B CG1 1 
ATOM   2610 C  CG2 . VAL B 2 27  ? -35.168 2.38    4.245   1   61.54  ? 197 VAL B CG2 1 
ATOM   2611 N  N   . GLY B 2 28  ? -34.762 6.26    6.653   1   61.87  ? 198 GLY B N   1 
ATOM   2612 C  CA  . GLY B 2 28  ? -35.072 7.675   6.801   1   80.67  ? 198 GLY B CA  1 
ATOM   2613 C  C   . GLY B 2 28  ? -34.061 8.454   7.644   1   84.94  ? 198 GLY B C   1 
ATOM   2614 O  O   . GLY B 2 28  ? -34.464 9.419   8.303   1   90.66  ? 198 GLY B O   1 
ATOM   2615 N  N   . TYR B 2 29  ? -32.887 8.083   7.859   1   69.36  ? 199 TYR B N   1 
ATOM   2616 C  CA  . TYR B 2 29  ? -31.99  8.687   8.89    1   60.25  ? 199 TYR B CA  1 
ATOM   2617 C  C   . TYR B 2 29  ? -31.496 10.067  8.587   1   59.27  ? 199 TYR B C   1 
ATOM   2618 O  O   . TYR B 2 29  ? -31.079 10.749  9.532   1   58.54  ? 199 TYR B O   1 
ATOM   2619 C  CB  . TYR B 2 29  ? -30.786 7.752   9.082   1   52.99  ? 199 TYR B CB  1 
ATOM   2620 C  CG  . TYR B 2 29  ? -29.581 7.843   8.152   1   47.42  ? 199 TYR B CG  1 
ATOM   2621 C  CD1 . TYR B 2 29  ? -28.695 8.911   8.205   1   49.63  ? 199 TYR B CD1 1 
ATOM   2622 C  CD2 . TYR B 2 29  ? -29.293 6.82    7.261   1   46.78  ? 199 TYR B CD2 1 
ATOM   2623 C  CE1 . TYR B 2 29  ? -27.602 8.991   7.363   1   50.43  ? 199 TYR B CE1 1 
ATOM   2624 C  CE2 . TYR B 2 29  ? -28.193 6.877   6.424   1   52.8   ? 199 TYR B CE2 1 
ATOM   2625 C  CZ  . TYR B 2 29  ? -27.343 7.965   6.476   1   52.75  ? 199 TYR B CZ  1 
ATOM   2626 O  OH  . TYR B 2 29  ? -26.258 8.034   5.656   1   54.4   ? 199 TYR B OH  1 
ATOM   2627 N  N   . MET B 2 30  ? -31.484 10.431  7.248   1   56.04  ? 200 MET B N   1 
ATOM   2628 C  CA  . MET B 2 30  ? -30.913 11.738  6.966   1   60.11  ? 200 MET B CA  1 
ATOM   2629 C  C   . MET B 2 30  ? -31.804 12.877  7.477   1   64.74  ? 200 MET B C   1 
ATOM   2630 O  O   . MET B 2 30  ? -31.3   13.908  7.913   1   63.22  ? 200 MET B O   1 
ATOM   2631 C  CB  . MET B 2 30  ? -30.568 11.88   5.487   1   57.88  ? 200 MET B CB  1 
ATOM   2632 C  CG  . MET B 2 30  ? -29.603 13.016  5.217   1   64.73  ? 200 MET B CG  1 
ATOM   2633 S  SD  . MET B 2 30  ? -28.015 12.93   6.068   1   67.32  ? 200 MET B SD  1 
ATOM   2634 C  CE  . MET B 2 30  ? -27.064 11.778  5.077   1   66.48  ? 200 MET B CE  1 
ATOM   2635 N  N   . LYS B 2 31  ? -33.125 12.677  7.458   1   69.28  ? 201 LYS B N   1 
ATOM   2636 C  CA  . LYS B 2 31  ? -34.073 13.634  8.013   1   71.86  ? 201 LYS B CA  1 
ATOM   2637 C  C   . LYS B 2 31  ? -33.865 13.788  9.517   1   68.96  ? 201 LYS B C   1 
ATOM   2638 O  O   . LYS B 2 31  ? -34.095 14.858  10.073  1   74.53  ? 201 LYS B O   1 
ATOM   2639 C  CB  . LYS B 2 31  ? -35.526 13.202  7.796   1   77.05  ? 201 LYS B CB  1 
ATOM   2640 C  CG  . LYS B 2 31  ? -35.995 13.195  6.351   1   95.42  ? 201 LYS B CG  1 
ATOM   2641 C  CD  . LYS B 2 31  ? -37.441 12.737  6.16    1   111.03 ? 201 LYS B CD  1 
ATOM   2642 C  CE  . LYS B 2 31  ? -37.892 12.761  4.721   1   113.84 ? 201 LYS B CE  1 
ATOM   2643 N  NZ  . LYS B 2 31  ? -39.279 12.292  4.575   1   106.65 ? 201 LYS B NZ  1 
ATOM   2644 N  N   . LYS B 2 32  ? -33.429 12.71   10.177  1   73.36  ? 202 LYS B N   1 
ATOM   2645 C  CA  . LYS B 2 32  ? -33.176 12.704  11.613  1   72.7   ? 202 LYS B CA  1 
ATOM   2646 C  C   . LYS B 2 32  ? -31.767 13.23   11.92   1   69.12  ? 202 LYS B C   1 
ATOM   2647 O  O   . LYS B 2 32  ? -31.392 13.3    13.084  1   66.29  ? 202 LYS B O   1 
ATOM   2648 C  CB  . LYS B 2 32  ? -33.395 11.317  12.237  1   80.63  ? 202 LYS B CB  1 
ATOM   2649 C  CG  . LYS B 2 32  ? -34.848 10.805  12.239  1   93.13  ? 202 LYS B CG  1 
ATOM   2650 C  CD  . LYS B 2 32  ? -35.161 9.426   12.818  1   94.81  ? 202 LYS B CD  1 
ATOM   2651 C  CE  . LYS B 2 32  ? -36.645 9.159   12.731  1   112.35 ? 202 LYS B CE  1 
ATOM   2652 N  NZ  . LYS B 2 32  ? -37.164 7.87    13.216  1   104.51 ? 202 LYS B NZ  1 
ATOM   2653 N  N   . GLN B 2 33  ? -30.958 13.569  10.9    1   62.99  ? 203 GLN B N   1 
ATOM   2654 C  CA  . GLN B 2 33  ? -29.644 14.163  11.152  1   57.28  ? 203 GLN B CA  1 
ATOM   2655 C  C   . GLN B 2 33  ? -29.765 15.688  11.123  1   58.06  ? 203 GLN B C   1 
ATOM   2656 O  O   . GLN B 2 33  ? -30.091 16.268  10.097  1   57.72  ? 203 GLN B O   1 
ATOM   2657 C  CB  . GLN B 2 33  ? -28.605 13.672  10.145  1   52.92  ? 203 GLN B CB  1 
ATOM   2658 C  CG  . GLN B 2 33  ? -28.204 12.215  10.337  1   50.98  ? 203 GLN B CG  1 
ATOM   2659 C  CD  . GLN B 2 33  ? -27.078 11.997  11.323  1   52.98  ? 203 GLN B CD  1 
ATOM   2660 O  OE1 . GLN B 2 33  ? -26.428 12.943  11.771  1   50.09  ? 203 GLN B OE1 1 
ATOM   2661 N  NE2 . GLN B 2 33  ? -26.826 10.736  11.663  1   54     ? 203 GLN B NE2 1 
ATOM   2662 N  N   . PRO B 2 34  ? -29.563 16.393  12.253  1   61.21  ? 204 PRO B N   1 
ATOM   2663 C  CA  . PRO B 2 34  ? -29.764 17.84   12.305  1   60.59  ? 204 PRO B CA  1 
ATOM   2664 C  C   . PRO B 2 34  ? -28.844 18.649  11.407  1   57.32  ? 204 PRO B C   1 
ATOM   2665 O  O   . PRO B 2 34  ? -29.281 19.673  10.917  1   61.38  ? 204 PRO B O   1 
ATOM   2666 C  CB  . PRO B 2 34  ? -29.542 18.197  13.782  1   62.23  ? 204 PRO B CB  1 
ATOM   2667 C  CG  . PRO B 2 34  ? -28.674 17.07   14.311  1   61.96  ? 204 PRO B CG  1 
ATOM   2668 C  CD  . PRO B 2 34  ? -29.169 15.839  13.556  1   62.61  ? 204 PRO B CD  1 
ATOM   2669 N  N   . ASP B 2 35  ? -27.596 18.188  11.197  1   59.12  ? 205 ASP B N   1 
ATOM   2670 C  CA  . ASP B 2 35  ? -26.551 19.057  10.674  1   57.26  ? 205 ASP B CA  1 
ATOM   2671 C  C   . ASP B 2 35  ? -25.949 18.606  9.352   1   58.65  ? 205 ASP B C   1 
ATOM   2672 O  O   . ASP B 2 35  ? -25.106 19.321  8.811   1   65.26  ? 205 ASP B O   1 
ATOM   2673 C  CB  . ASP B 2 35  ? -25.362 19.215  11.599  1   58.22  ? 205 ASP B CB  1 
ATOM   2674 C  CG  . ASP B 2 35  ? -24.689 20.558  11.377  1   65.51  ? 205 ASP B CG  1 
ATOM   2675 O  OD1 . ASP B 2 35  ? -25.44  21.556  11.291  1   64.42  ? 205 ASP B OD1 1 
ATOM   2676 O  OD2 . ASP B 2 35  ? -23.445 20.594  11.272  1   63.09  ? 205 ASP B OD2 1 
ATOM   2677 N  N   . ILE B 2 36  ? -26.358 17.437  8.858   1   61.01  ? 206 ILE B N   1 
ATOM   2678 C  CA  . ILE B 2 36  ? -25.863 16.89   7.602   1   59.2   ? 206 ILE B CA  1 
ATOM   2679 C  C   . ILE B 2 36  ? -27.039 16.507  6.692   1   61.1   ? 206 ILE B C   1 
ATOM   2680 O  O   . ILE B 2 36  ? -28.178 16.391  7.157   1   53.83  ? 206 ILE B O   1 
ATOM   2681 C  CB  . ILE B 2 36  ? -24.849 15.752  7.838   1   57.93  ? 206 ILE B CB  1 
ATOM   2682 C  CG1 . ILE B 2 36  ? -25.473 14.544  8.51    1   54.75  ? 206 ILE B CG1 1 
ATOM   2683 C  CG2 . ILE B 2 36  ? -23.632 16.264  8.616   1   57.33  ? 206 ILE B CG2 1 
ATOM   2684 C  CD1 . ILE B 2 36  ? -24.49  13.41   8.721   1   59.25  ? 206 ILE B CD1 1 
ATOM   2685 N  N   . THR B 2 37  ? -26.736 16.354  5.383   1   60.68  ? 207 THR B N   1 
ATOM   2686 C  CA  . THR B 2 37  ? -27.706 16.24   4.295   1   57.05  ? 207 THR B CA  1 
ATOM   2687 C  C   . THR B 2 37  ? -27.189 15.216  3.289   1   59.62  ? 207 THR B C   1 
ATOM   2688 O  O   . THR B 2 37  ? -25.981 14.966  3.229   1   62.24  ? 207 THR B O   1 
ATOM   2689 C  CB  . THR B 2 37  ? -27.9   17.579  3.563   1   54.95  ? 207 THR B CB  1 
ATOM   2690 O  OG1 . THR B 2 37  ? -26.678 17.837  2.867   1   49.84  ? 207 THR B OG1 1 
ATOM   2691 C  CG2 . THR B 2 37  ? -28.305 18.751  4.448   1   49.77  ? 207 THR B CG2 1 
ATOM   2692 N  N   . ASN B 2 38  ? -28.111 14.682  2.471   1   56.52  ? 208 ASN B N   1 
ATOM   2693 C  CA  . ASN B 2 38  ? -27.79  13.784  1.374   1   57.1   ? 208 ASN B CA  1 
ATOM   2694 C  C   . ASN B 2 38  ? -26.643 14.345  0.531   1   56.18  ? 208 ASN B C   1 
ATOM   2695 O  O   . ASN B 2 38  ? -25.739 13.604  0.104   1   49.19  ? 208 ASN B O   1 
ATOM   2696 C  CB  . ASN B 2 38  ? -29.016 13.5    0.515   1   59.99  ? 208 ASN B CB  1 
ATOM   2697 C  CG  . ASN B 2 38  ? -30.056 12.73   1.288   1   62.12  ? 208 ASN B CG  1 
ATOM   2698 O  OD1 . ASN B 2 38  ? -29.694 11.859  2.091   1   65.6   ? 208 ASN B OD1 1 
ATOM   2699 N  ND2 . ASN B 2 38  ? -31.327 13.03   1.06    1   55.75  ? 208 ASN B ND2 1 
ATOM   2700 N  N   . SER B 2 39  ? -26.671 15.672  0.369   1   52.52  ? 209 SER B N   1 
ATOM   2701 C  CA  . SER B 2 39  ? -25.699 16.366  -0.454  1   58.43  ? 209 SER B CA  1 
ATOM   2702 C  C   . SER B 2 39  ? -24.292 16.234  0.129   1   57.64  ? 209 SER B C   1 
ATOM   2703 O  O   . SER B 2 39  ? -23.338 15.971  -0.604  1   57.68  ? 209 SER B O   1 
ATOM   2704 C  CB  . SER B 2 39  ? -26.124 17.793  -0.647  1   61.22  ? 209 SER B CB  1 
ATOM   2705 O  OG  . SER B 2 39  ? -25.014 18.588  -1.028  1   66.67  ? 209 SER B OG  1 
ATOM   2706 N  N   . MET B 2 40  ? -24.178 16.398  1.454   1   59.02  ? 210 MET B N   1 
ATOM   2707 C  CA  . MET B 2 40  ? -22.898 16.282  2.138   1   57.88  ? 210 MET B CA  1 
ATOM   2708 C  C   . MET B 2 40  ? -22.42  14.835  2.102   1   54.97  ? 210 MET B C   1 
ATOM   2709 O  O   . MET B 2 40  ? -21.221 14.578  1.995   1   56.59  ? 210 MET B O   1 
ATOM   2710 C  CB  . MET B 2 40  ? -22.977 16.758  3.592   1   57.61  ? 210 MET B CB  1 
ATOM   2711 C  CG  . MET B 2 40  ? -23.415 18.2    3.711   1   60.59  ? 210 MET B CG  1 
ATOM   2712 S  SD  . MET B 2 40  ? -23.458 18.704  5.437   1   61.83  ? 210 MET B SD  1 
ATOM   2713 C  CE  . MET B 2 40  ? -24.273 20.307  5.304   1   58.21  ? 210 MET B CE  1 
ATOM   2714 N  N   . ARG B 2 41  ? -23.367 13.898  2.187   1   52.56  ? 211 ARG B N   1 
ATOM   2715 C  CA  . ARG B 2 41  ? -23.039 12.481  2.139   1   51.48  ? 211 ARG B CA  1 
ATOM   2716 C  C   . ARG B 2 41  ? -22.481 12.139  0.756   1   53.6   ? 211 ARG B C   1 
ATOM   2717 O  O   . ARG B 2 41  ? -21.596 11.291  0.642   1   55.43  ? 211 ARG B O   1 
ATOM   2718 C  CB  . ARG B 2 41  ? -24.278 11.644  2.483   1   47.53  ? 211 ARG B CB  1 
ATOM   2719 C  CG  . ARG B 2 41  ? -24.048 10.145  2.47    1   47.66  ? 211 ARG B CG  1 
ATOM   2720 C  CD  . ARG B 2 41  ? -25.359 9.375   2.474   1   51.26  ? 211 ARG B CD  1 
ATOM   2721 N  NE  . ARG B 2 41  ? -25.17  7.949   2.175   1   49.97  ? 211 ARG B NE  1 
ATOM   2722 C  CZ  . ARG B 2 41  ? -24.849 7.46    0.982   1   50.73  ? 211 ARG B CZ  1 
ATOM   2723 N  NH1 . ARG B 2 41  ? -24.807 8.271   -0.064  1   51.36  ? 211 ARG B NH1 1 
ATOM   2724 N  NH2 . ARG B 2 41  ? -24.55  6.17    0.844   1   47.8   ? 211 ARG B NH2 1 
ATOM   2725 N  N   . ALA B 2 42  ? -23.045 12.761  -0.293  1   53.14  ? 212 ALA B N   1 
ATOM   2726 C  CA  . ALA B 2 42  ? -22.646 12.477  -1.662  1   48.48  ? 212 ALA B CA  1 
ATOM   2727 C  C   . ALA B 2 42  ? -21.209 12.959  -1.848  1   54.01  ? 212 ALA B C   1 
ATOM   2728 O  O   . ALA B 2 42  ? -20.4   12.26   -2.461  1   52.63  ? 212 ALA B O   1 
ATOM   2729 C  CB  . ALA B 2 42  ? -23.585 13.163  -2.626  1   48.9   ? 212 ALA B CB  1 
ATOM   2730 N  N   . ILE B 2 43  ? -20.904 14.142  -1.282  1   49.55  ? 213 ILE B N   1 
ATOM   2731 C  CA  . ILE B 2 43  ? -19.561 14.694  -1.315  1   50.1   ? 213 ILE B CA  1 
ATOM   2732 C  C   . ILE B 2 43  ? -18.571 13.726  -0.656  1   49.71  ? 213 ILE B C   1 
ATOM   2733 O  O   . ILE B 2 43  ? -17.455 13.544  -1.145  1   50.38  ? 213 ILE B O   1 
ATOM   2734 C  CB  . ILE B 2 43  ? -19.548 16.091  -0.67   1   51.81  ? 213 ILE B CB  1 
ATOM   2735 C  CG1 . ILE B 2 43  ? -20.333 17.114  -1.511  1   50.38  ? 213 ILE B CG1 1 
ATOM   2736 C  CG2 . ILE B 2 43  ? -18.116 16.561  -0.39   1   51.41  ? 213 ILE B CG2 1 
ATOM   2737 C  CD1 . ILE B 2 43  ? -20.49  18.477  -0.851  1   46.1   ? 213 ILE B CD1 1 
ATOM   2738 N  N   . LEU B 2 44  ? -18.972 13.127  0.467   1   46.18  ? 214 LEU B N   1 
ATOM   2739 C  CA  . LEU B 2 44  ? -18.11  12.224  1.215   1   48.46  ? 214 LEU B CA  1 
ATOM   2740 C  C   . LEU B 2 44  ? -17.835 10.972  0.383   1   49.15  ? 214 LEU B C   1 
ATOM   2741 O  O   . LEU B 2 44  ? -16.678 10.559  0.216   1   47.08  ? 214 LEU B O   1 
ATOM   2742 C  CB  . LEU B 2 44  ? -18.716 11.888  2.579   1   46.66  ? 214 LEU B CB  1 
ATOM   2743 C  CG  . LEU B 2 44  ? -17.992 10.826  3.407   1   47.71  ? 214 LEU B CG  1 
ATOM   2744 C  CD1 . LEU B 2 44  ? -16.693 11.384  3.928   1   52.27  ? 214 LEU B CD1 1 
ATOM   2745 C  CD2 . LEU B 2 44  ? -18.846 10.36   4.577   1   46.58  ? 214 LEU B CD2 1 
ATOM   2746 N  N   . VAL B 2 45  ? -18.902 10.399  -0.175  1   45.41  ? 215 VAL B N   1 
ATOM   2747 C  CA  . VAL B 2 45  ? -18.753 9.146   -0.889  1   48.14  ? 215 VAL B CA  1 
ATOM   2748 C  C   . VAL B 2 45  ? -17.891 9.362   -2.133  1   51.24  ? 215 VAL B C   1 
ATOM   2749 O  O   . VAL B 2 45  ? -17.011 8.554   -2.418  1   56.37  ? 215 VAL B O   1 
ATOM   2750 C  CB  . VAL B 2 45  ? -20.105 8.489   -1.211  1   50.45  ? 215 VAL B CB  1 
ATOM   2751 C  CG1 . VAL B 2 45  ? -19.903 7.219   -2.021  1   45.01  ? 215 VAL B CG1 1 
ATOM   2752 C  CG2 . VAL B 2 45  ? -20.932 8.235   0.057   1   45.69  ? 215 VAL B CG2 1 
ATOM   2753 N  N   . ASP B 2 46  ? -18.124 10.469  -2.852  1   50.93  ? 216 ASP B N   1 
ATOM   2754 C  CA  . ASP B 2 46  ? -17.349 10.826  -4.031  1   47.63  ? 216 ASP B CA  1 
ATOM   2755 C  C   . ASP B 2 46  ? -15.87  10.934  -3.662  1   50.97  ? 216 ASP B C   1 
ATOM   2756 O  O   . ASP B 2 46  ? -15.001 10.533  -4.443  1   55.21  ? 216 ASP B O   1 
ATOM   2757 C  CB  . ASP B 2 46  ? -17.831 12.141  -4.614  1   49.97  ? 216 ASP B CB  1 
ATOM   2758 C  CG  . ASP B 2 46  ? -17.199 12.548  -5.933  1   50.08  ? 216 ASP B CG  1 
ATOM   2759 O  OD1 . ASP B 2 46  ? -17.632 12.03   -6.977  1   53.99  ? 216 ASP B OD1 1 
ATOM   2760 O  OD2 . ASP B 2 46  ? -16.249 13.338  -5.899  1   48.25  ? 216 ASP B OD2 1 
ATOM   2761 N  N   . TRP B 2 47  ? -15.593 11.5    -2.479  1   49.55  ? 217 TRP B N   1 
ATOM   2762 C  CA  . TRP B 2 47  ? -14.228 11.615  -1.989  1   50.39  ? 217 TRP B CA  1 
ATOM   2763 C  C   . TRP B 2 47  ? -13.631 10.227  -1.724  1   54.6   ? 217 TRP B C   1 
ATOM   2764 O  O   . TRP B 2 47  ? -12.495 9.936   -2.111  1   57.42  ? 217 TRP B O   1 
ATOM   2765 C  CB  . TRP B 2 47  ? -14.191 12.528  -0.76   1   45.4   ? 217 TRP B CB  1 
ATOM   2766 C  CG  . TRP B 2 47  ? -12.853 12.6    -0.094  1   44.45  ? 217 TRP B CG  1 
ATOM   2767 C  CD1 . TRP B 2 47  ? -11.731 13.218  -0.566  1   46.2   ? 217 TRP B CD1 1 
ATOM   2768 C  CD2 . TRP B 2 47  ? -12.492 12.018  1.172   1   41.42  ? 217 TRP B CD2 1 
ATOM   2769 N  NE1 . TRP B 2 47  ? -10.698 13.077  0.327   1   45.33  ? 217 TRP B NE1 1 
ATOM   2770 C  CE2 . TRP B 2 47  ? -11.137 12.341  1.399   1   44.67  ? 217 TRP B CE2 1 
ATOM   2771 C  CE3 . TRP B 2 47  ? -13.18  11.278  2.125   1   42.73  ? 217 TRP B CE3 1 
ATOM   2772 C  CZ2 . TRP B 2 47  ? -10.45  11.927  2.534   1   45.86  ? 217 TRP B CZ2 1 
ATOM   2773 C  CZ3 . TRP B 2 47  ? -12.498 10.857  3.245   1   48.92  ? 217 TRP B CZ3 1 
ATOM   2774 C  CH2 . TRP B 2 47  ? -11.154 11.177  3.445   1   48.85  ? 217 TRP B CH2 1 
ATOM   2775 N  N   . LEU B 2 48  ? -14.408 9.348   -1.085  1   54.41  ? 218 LEU B N   1 
ATOM   2776 C  CA  . LEU B 2 48  ? -13.928 8.002   -0.801  1   51.89  ? 218 LEU B CA  1 
ATOM   2777 C  C   . LEU B 2 48  ? -13.665 7.249   -2.104  1   52.7   ? 218 LEU B C   1 
ATOM   2778 O  O   . LEU B 2 48  ? -12.827 6.36    -2.12   1   53.51  ? 218 LEU B O   1 
ATOM   2779 C  CB  . LEU B 2 48  ? -14.941 7.271   0.07    1   46.56  ? 218 LEU B CB  1 
ATOM   2780 C  CG  . LEU B 2 48  ? -15.072 7.796   1.497   1   48.25  ? 218 LEU B CG  1 
ATOM   2781 C  CD1 . LEU B 2 48  ? -16.189 7.08    2.217   1   45.71  ? 218 LEU B CD1 1 
ATOM   2782 C  CD2 . LEU B 2 48  ? -13.744 7.657   2.231   1   45.41  ? 218 LEU B CD2 1 
ATOM   2783 N  N   . VAL B 2 49  ? -14.369 7.605   -3.189  1   49.14  ? 219 VAL B N   1 
ATOM   2784 C  CA  . VAL B 2 49  ? -14.102 7.01    -4.487  1   47.71  ? 219 VAL B CA  1 
ATOM   2785 C  C   . VAL B 2 49  ? -12.709 7.45    -4.938  1   53.46  ? 219 VAL B C   1 
ATOM   2786 O  O   . VAL B 2 49  ? -11.928 6.634   -5.397  1   56.06  ? 219 VAL B O   1 
ATOM   2787 C  CB  . VAL B 2 49  ? -15.178 7.403   -5.511  1   45.76  ? 219 VAL B CB  1 
ATOM   2788 C  CG1 . VAL B 2 49  ? -14.864 6.89    -6.904  1   45.28  ? 219 VAL B CG1 1 
ATOM   2789 C  CG2 . VAL B 2 49  ? -16.561 6.944   -5.082  1   44.86  ? 219 VAL B CG2 1 
ATOM   2790 N  N   . GLU B 2 50  ? -12.386 8.738   -4.781  1   57.02  ? 220 GLU B N   1 
ATOM   2791 C  CA  . GLU B 2 50  ? -11.067 9.241   -5.124  1   55.44  ? 220 GLU B CA  1 
ATOM   2792 C  C   . GLU B 2 50  ? -10     8.604   -4.24   1   55.79  ? 220 GLU B C   1 
ATOM   2793 O  O   . GLU B 2 50  ? -8.91   8.343   -4.716  1   60.4   ? 220 GLU B O   1 
ATOM   2794 C  CB  . GLU B 2 50  ? -10.961 10.748  -4.899  1   57.15  ? 220 GLU B CB  1 
ATOM   2795 C  CG  . GLU B 2 50  ? -11.592 11.571  -6.009  1   66.88  ? 220 GLU B CG  1 
ATOM   2796 C  CD  . GLU B 2 50  ? -11.229 13.034  -5.927  1   73.83  ? 220 GLU B CD  1 
ATOM   2797 O  OE1 . GLU B 2 50  ? -11.215 13.681  -7.002  1   84.3   ? 220 GLU B OE1 1 
ATOM   2798 O  OE2 . GLU B 2 50  ? -11.007 13.515  -4.79   1   72.93  ? 220 GLU B OE2 1 
ATOM   2799 N  N   . VAL B 2 51  ? -10.267 8.446   -2.94   1   50.29  ? 221 VAL B N   1 
ATOM   2800 C  CA  . VAL B 2 51  ? -9.295  7.831   -2.047  1   48.92  ? 221 VAL B CA  1 
ATOM   2801 C  C   . VAL B 2 51  ? -9.008  6.395   -2.501  1   53.05  ? 221 VAL B C   1 
ATOM   2802 O  O   . VAL B 2 51  ? -7.844  5.998   -2.583  1   55.77  ? 221 VAL B O   1 
ATOM   2803 C  CB  . VAL B 2 51  ? -9.793  7.892   -0.594  1   45.69  ? 221 VAL B CB  1 
ATOM   2804 C  CG1 . VAL B 2 51  ? -8.963  7.01    0.332   1   42.51  ? 221 VAL B CG1 1 
ATOM   2805 C  CG2 . VAL B 2 51  ? -9.893  9.333   -0.098  1   44.06  ? 221 VAL B CG2 1 
ATOM   2806 N  N   . GLY B 2 52  ? -10.056 5.669   -2.875  1   47.48  ? 222 GLY B N   1 
ATOM   2807 C  CA  . GLY B 2 52  ? -9.896  4.278   -3.32   1   46.83  ? 222 GLY B CA  1 
ATOM   2808 C  C   . GLY B 2 52  ? -9.021  4.16    -4.543  1   56.07  ? 222 GLY B C   1 
ATOM   2809 O  O   . GLY B 2 52  ? -8.284  3.171   -4.638  1   62.84  ? 222 GLY B O   1 
ATOM   2810 N  N   . GLU B 2 53  ? -9.095  5.128   -5.449  1   57.29  ? 223 GLU B N   1 
ATOM   2811 C  CA  . GLU B 2 53  ? -8.327  5.03    -6.716  1   66.92  ? 223 GLU B CA  1 
ATOM   2812 C  C   . GLU B 2 53  ? -6.889  5.517   -6.491  1   62.15  ? 223 GLU B C   1 
ATOM   2813 O  O   . GLU B 2 53  ? -5.981  4.999   -7.156  1   70     ? 223 GLU B O   1 
ATOM   2814 C  CB  . GLU B 2 53  ? -9.046  5.788   -7.829  1   68.61  ? 223 GLU B CB  1 
ATOM   2815 C  CG  . GLU B 2 53  ? -10.065 4.936   -8.579  1   76.48  ? 223 GLU B CG  1 
ATOM   2816 C  CD  . GLU B 2 53  ? -9.861  3.43    -8.593  1   98.1   ? 223 GLU B CD  1 
ATOM   2817 O  OE1 . GLU B 2 53  ? -9.236  2.93    -9.547  1   115.5  ? 223 GLU B OE1 1 
ATOM   2818 O  OE2 . GLU B 2 53  ? -10.347 2.747   -7.668  1   87.8   ? 223 GLU B OE2 1 
ATOM   2819 N  N   . GLU B 2 54  ? -6.701  6.454   -5.57   1   64.7   ? 224 GLU B N   1 
ATOM   2820 C  CA  . GLU B 2 54  ? -5.341  6.954   -5.261  1   63.18  ? 224 GLU B CA  1 
ATOM   2821 C  C   . GLU B 2 54  ? -4.545  5.834   -4.584  1   58.18  ? 224 GLU B C   1 
ATOM   2822 O  O   . GLU B 2 54  ? -3.325  5.763   -4.8    1   64.66  ? 224 GLU B O   1 
ATOM   2823 C  CB  . GLU B 2 54  ? -5.458  8.213   -4.405  1   59.97  ? 224 GLU B CB  1 
ATOM   2824 C  CG  . GLU B 2 54  ? -4.175  8.592   -3.673  1   72.66  ? 224 GLU B CG  1 
ATOM   2825 C  CD  . GLU B 2 54  ? -3.192  9.378   -4.517  1   87.15  ? 224 GLU B CD  1 
ATOM   2826 O  OE1 . GLU B 2 54  ? -3.64   10.074  -5.449  1   92.73  ? 224 GLU B OE1 1 
ATOM   2827 O  OE2 . GLU B 2 54  ? -1.979  9.294   -4.243  1   96.29  ? 224 GLU B OE2 1 
ATOM   2828 N  N   . TYR B 2 55  ? -5.215  4.978   -3.822  1   54.11  ? 225 TYR B N   1 
ATOM   2829 C  CA  . TYR B 2 55  ? -4.493  3.946   -3.091  1   57.96  ? 225 TYR B CA  1 
ATOM   2830 C  C   . TYR B 2 55  ? -4.713  2.602   -3.769  1   57.67  ? 225 TYR B C   1 
ATOM   2831 O  O   . TYR B 2 55  ? -4.2    1.582   -3.318  1   55.97  ? 225 TYR B O   1 
ATOM   2832 C  CB  . TYR B 2 55  ? -4.83   3.947   -1.596  1   57.37  ? 225 TYR B CB  1 
ATOM   2833 C  CG  . TYR B 2 55  ? -4.204  5.119   -0.854  1   68.75  ? 225 TYR B CG  1 
ATOM   2834 C  CD1 . TYR B 2 55  ? -4.858  6.346   -0.781  1   71.5   ? 225 TYR B CD1 1 
ATOM   2835 C  CD2 . TYR B 2 55  ? -2.941  5.013   -0.274  1   68.62  ? 225 TYR B CD2 1 
ATOM   2836 C  CE1 . TYR B 2 55  ? -4.275  7.426   -0.139  1   69.99  ? 225 TYR B CE1 1 
ATOM   2837 C  CE2 . TYR B 2 55  ? -2.356  6.091   0.372   1   69.22  ? 225 TYR B CE2 1 
ATOM   2838 C  CZ  . TYR B 2 55  ? -3.029  7.299   0.445   1   67.65  ? 225 TYR B CZ  1 
ATOM   2839 O  OH  . TYR B 2 55  ? -2.477  8.368   1.096   1   74.68  ? 225 TYR B OH  1 
ATOM   2840 N  N   . LYS B 2 56  ? -5.45   2.635   -4.883  1   59.54  ? 226 LYS B N   1 
ATOM   2841 C  CA  . LYS B 2 56  ? -5.662  1.449   -5.698  1   60.53  ? 226 LYS B CA  1 
ATOM   2842 C  C   . LYS B 2 56  ? -6.275  0.359   -4.819  1   59.58  ? 226 LYS B C   1 
ATOM   2843 O  O   . LYS B 2 56  ? -5.785  -0.768  -4.755  1   59.27  ? 226 LYS B O   1 
ATOM   2844 C  CB  . LYS B 2 56  ? -4.428  1.063   -6.529  1   68.75  ? 226 LYS B CB  1 
ATOM   2845 C  CG  . LYS B 2 56  ? -3.863  2.15    -7.453  1   79.31  ? 226 LYS B CG  1 
ATOM   2846 C  CD  . LYS B 2 56  ? -3.513  1.813   -8.904  1   99.62  ? 226 LYS B CD  1 
ATOM   2847 C  CE  . LYS B 2 56  ? -2.371  0.881   -9.189  1   104.58 ? 226 LYS B CE  1 
ATOM   2848 N  NZ  . LYS B 2 56  ? -1.078  1.491   -8.873  1   108.03 ? 226 LYS B NZ  1 
ATOM   2849 N  N   . LEU B 2 57  ? -7.362  0.734   -4.13   1   56.35  ? 227 LEU B N   1 
ATOM   2850 C  CA  . LEU B 2 57  ? -8.101  -0.146  -3.245  1   48.84  ? 227 LEU B CA  1 
ATOM   2851 C  C   . LEU B 2 57  ? -9.092  -0.911  -4.104  1   52.32  ? 227 LEU B C   1 
ATOM   2852 O  O   . LEU B 2 57  ? -9.47   -0.438  -5.171  1   63.29  ? 227 LEU B O   1 
ATOM   2853 C  CB  . LEU B 2 57  ? -8.843  0.696   -2.208  1   48.31  ? 227 LEU B CB  1 
ATOM   2854 C  CG  . LEU B 2 57  ? -7.972  1.55    -1.281  1   48.28  ? 227 LEU B CG  1 
ATOM   2855 C  CD1 . LEU B 2 57  ? -8.828  2.288   -0.269  1   44.1   ? 227 LEU B CD1 1 
ATOM   2856 C  CD2 . LEU B 2 57  ? -6.951  0.674   -0.563  1   47.27  ? 227 LEU B CD2 1 
ATOM   2857 N  N   . GLN B 2 58  ? -9.523  -2.067  -3.6    1   48.81  ? 228 GLN B N   1 
ATOM   2858 C  CA  . GLN B 2 58  ? -10.585 -2.858  -4.188  1   43.16  ? 228 GLN B CA  1 
ATOM   2859 C  C   . GLN B 2 58  ? -11.86  -2.035  -4.148  1   44.81  ? 228 GLN B C   1 
ATOM   2860 O  O   . GLN B 2 58  ? -12.069 -1.279  -3.191  1   49.95  ? 228 GLN B O   1 
ATOM   2861 C  CB  . GLN B 2 58  ? -10.777 -4.117  -3.336  1   42.68  ? 228 GLN B CB  1 
ATOM   2862 C  CG  . GLN B 2 58  ? -9.614  -5.097  -3.403  1   46.44  ? 228 GLN B CG  1 
ATOM   2863 C  CD  . GLN B 2 58  ? -9.403  -5.543  -4.83   1   48.51  ? 228 GLN B CD  1 
ATOM   2864 O  OE1 . GLN B 2 58  ? -10.317 -6.062  -5.475  1   55.93  ? 228 GLN B OE1 1 
ATOM   2865 N  NE2 . GLN B 2 58  ? -8.228  -5.254  -5.357  1   46.54  ? 228 GLN B NE2 1 
ATOM   2866 N  N   . ASN B 2 59  ? -12.717 -2.242  -5.156  1   43.19  ? 229 ASN B N   1 
ATOM   2867 C  CA  . ASN B 2 59  ? -14.073 -1.714  -5.15   1   44.79  ? 229 ASN B CA  1 
ATOM   2868 C  C   . ASN B 2 59  ? -14.875 -2.238  -3.947  1   49.78  ? 229 ASN B C   1 
ATOM   2869 O  O   . ASN B 2 59  ? -15.679 -1.484  -3.368  1   51.56  ? 229 ASN B O   1 
ATOM   2870 C  CB  . ASN B 2 59  ? -14.789 -1.964  -6.47   1   43.4   ? 229 ASN B CB  1 
ATOM   2871 C  CG  . ASN B 2 59  ? -14.244 -1.181  -7.644  1   49.27  ? 229 ASN B CG  1 
ATOM   2872 O  OD1 . ASN B 2 59  ? -13.404 -0.28   -7.509  1   50.2   ? 229 ASN B OD1 1 
ATOM   2873 N  ND2 . ASN B 2 59  ? -14.721 -1.527  -8.83   1   57.38  ? 229 ASN B ND2 1 
ATOM   2874 N  N   . GLU B 2 60  ? -14.659 -3.513  -3.558  1   40.74  ? 230 GLU B N   1 
ATOM   2875 C  CA  . GLU B 2 60  ? -15.375 -4.08   -2.418  1   40.06  ? 230 GLU B CA  1 
ATOM   2876 C  C   . GLU B 2 60  ? -15.176 -3.195  -1.175  1   45.48  ? 230 GLU B C   1 
ATOM   2877 O  O   . GLU B 2 60  ? -16.117 -2.96   -0.393  1   42.66  ? 230 GLU B O   1 
ATOM   2878 C  CB  . GLU B 2 60  ? -14.886 -5.505  -2.158  1   41.85  ? 230 GLU B CB  1 
ATOM   2879 C  CG  . GLU B 2 60  ? -15.521 -6.218  -0.967  1   37.5   ? 230 GLU B CG  1 
ATOM   2880 C  CD  . GLU B 2 60  ? -17.002 -6.474  -1.142  1   40.83  ? 230 GLU B CD  1 
ATOM   2881 O  OE1 . GLU B 2 60  ? -17.547 -6.285  -2.245  1   46.05  ? 230 GLU B OE1 1 
ATOM   2882 O  OE2 . GLU B 2 60  ? -17.627 -6.848  -0.141  1   41.46  ? 230 GLU B OE2 1 
ATOM   2883 N  N   . THR B 2 61  ? -13.936 -2.709  -0.999  1   39.96  ? 231 THR B N   1 
ATOM   2884 C  CA  . THR B 2 61  ? -13.579 -1.89   0.148   1   47.94  ? 231 THR B CA  1 
ATOM   2885 C  C   . THR B 2 61  ? -14.428 -0.618  0.177   1   49.32  ? 231 THR B C   1 
ATOM   2886 O  O   . THR B 2 61  ? -14.896 -0.204  1.243   1   44.09  ? 231 THR B O   1 
ATOM   2887 C  CB  . THR B 2 61  ? -12.087 -1.58   0.109   1   47.61  ? 231 THR B CB  1 
ATOM   2888 O  OG1 . THR B 2 61  ? -11.431 -2.837  0.035   1   42.43  ? 231 THR B OG1 1 
ATOM   2889 C  CG2 . THR B 2 61  ? -11.626 -0.865  1.363   1   51.14  ? 231 THR B CG2 1 
ATOM   2890 N  N   . LEU B 2 62  ? -14.611 -0.023  -1.011  1   46.72  ? 232 LEU B N   1 
ATOM   2891 C  CA  . LEU B 2 62  ? -15.39  1.189   -1.157  1   45.02  ? 232 LEU B CA  1 
ATOM   2892 C  C   . LEU B 2 62  ? -16.808 0.904   -0.696  1   43     ? 232 LEU B C   1 
ATOM   2893 O  O   . LEU B 2 62  ? -17.339 1.69    0.079   1   41.34  ? 232 LEU B O   1 
ATOM   2894 C  CB  . LEU B 2 62  ? -15.367 1.775   -2.572  1   48.21  ? 232 LEU B CB  1 
ATOM   2895 C  CG  . LEU B 2 62  ? -16.399 2.878   -2.86   1   47.21  ? 232 LEU B CG  1 
ATOM   2896 C  CD1 . LEU B 2 62  ? -16.164 4.155   -2.035  1   40.16  ? 232 LEU B CD1 1 
ATOM   2897 C  CD2 . LEU B 2 62  ? -16.464 3.194   -4.358  1   44.05  ? 232 LEU B CD2 1 
ATOM   2898 N  N   . HIS B 2 63  ? -17.391 -0.209  -1.178  1   41.06  ? 233 HIS B N   1 
ATOM   2899 C  CA  . HIS B 2 63  ? -18.768 -0.569  -0.859  1   38.87  ? 233 HIS B CA  1 
ATOM   2900 C  C   . HIS B 2 63  ? -18.958 -0.838  0.637   1   44.28  ? 233 HIS B C   1 
ATOM   2901 O  O   . HIS B 2 63  ? -20     -0.465  1.192   1   46.78  ? 233 HIS B O   1 
ATOM   2902 C  CB  . HIS B 2 63  ? -19.265 -1.75   -1.697  1   38.8   ? 233 HIS B CB  1 
ATOM   2903 C  CG  . HIS B 2 63  ? -19.715 -1.427  -3.098  1   47.24  ? 233 HIS B CG  1 
ATOM   2904 N  ND1 . HIS B 2 63  ? -18.836 -1.265  -4.165  1   48.21  ? 233 HIS B ND1 1 
ATOM   2905 C  CD2 . HIS B 2 63  ? -20.953 -1.253  -3.61   1   39.01  ? 233 HIS B CD2 1 
ATOM   2906 C  CE1 . HIS B 2 63  ? -19.528 -1.005  -5.276  1   40.98  ? 233 HIS B CE1 1 
ATOM   2907 N  NE2 . HIS B 2 63  ? -20.809 -0.993  -4.958  1   40.82  ? 233 HIS B NE2 1 
ATOM   2908 N  N   . LEU B 2 64  ? -17.972 -1.506  1.269   1   43.55  ? 234 LEU B N   1 
ATOM   2909 C  CA  . LEU B 2 64  ? -18.046 -1.851  2.682   1   40.77  ? 234 LEU B CA  1 
ATOM   2910 C  C   . LEU B 2 64  ? -18.076 -0.554  3.492   1   47.69  ? 234 LEU B C   1 
ATOM   2911 O  O   . LEU B 2 64  ? -18.845 -0.403  4.453   1   46.31  ? 234 LEU B O   1 
ATOM   2912 C  CB  . LEU B 2 64  ? -16.881 -2.753  3.09    1   37.43  ? 234 LEU B CB  1 
ATOM   2913 C  CG  . LEU B 2 64  ? -16.941 -4.213  2.615   1   40.19  ? 234 LEU B CG  1 
ATOM   2914 C  CD1 . LEU B 2 64  ? -15.641 -4.933  2.902   1   37.61  ? 234 LEU B CD1 1 
ATOM   2915 C  CD2 . LEU B 2 64  ? -18.086 -5.006  3.233   1   34.62  ? 234 LEU B CD2 1 
ATOM   2916 N  N   . ALA B 2 65  ? -17.244 0.402   3.066   1   42.8   ? 235 ALA B N   1 
ATOM   2917 C  CA  . ALA B 2 65  ? -17.073 1.629   3.823   1   44.28  ? 235 ALA B CA  1 
ATOM   2918 C  C   . ALA B 2 65  ? -18.383 2.426   3.875   1   47.04  ? 235 ALA B C   1 
ATOM   2919 O  O   . ALA B 2 65  ? -18.756 3.005   4.905   1   48.28  ? 235 ALA B O   1 
ATOM   2920 C  CB  . ALA B 2 65  ? -15.939 2.412   3.196   1   42.25  ? 235 ALA B CB  1 
ATOM   2921 N  N   . VAL B 2 66  ? -19.057 2.478   2.722   1   43.64  ? 236 VAL B N   1 
ATOM   2922 C  CA  . VAL B 2 66  ? -20.31  3.181   2.586   1   43.97  ? 236 VAL B CA  1 
ATOM   2923 C  C   . VAL B 2 66  ? -21.342 2.49    3.491   1   52.21  ? 236 VAL B C   1 
ATOM   2924 O  O   . VAL B 2 66  ? -22.135 3.161   4.156   1   55.91  ? 236 VAL B O   1 
ATOM   2925 C  CB  . VAL B 2 66  ? -20.711 3.24    1.096   1   44.46  ? 236 VAL B CB  1 
ATOM   2926 C  CG1 . VAL B 2 66  ? -22.08  3.876   0.896   1   44.77  ? 236 VAL B CG1 1 
ATOM   2927 C  CG2 . VAL B 2 66  ? -19.681 3.995   0.264   1   40.19  ? 236 VAL B CG2 1 
ATOM   2928 N  N   . ASN B 2 67  ? -21.31  1.148   3.546   1   49.7   ? 237 ASN B N   1 
ATOM   2929 C  CA  . ASN B 2 67  ? -22.217 0.385   4.398   1   45.23  ? 237 ASN B CA  1 
ATOM   2930 C  C   . ASN B 2 67  ? -21.987 0.786   5.85    1   44.78  ? 237 ASN B C   1 
ATOM   2931 O  O   . ASN B 2 67  ? -22.955 0.982   6.59    1   46.33  ? 237 ASN B O   1 
ATOM   2932 C  CB  . ASN B 2 67  ? -22.134 -1.127  4.153   1   38.84  ? 237 ASN B CB  1 
ATOM   2933 C  CG  . ASN B 2 67  ? -22.956 -1.904  5.147   1   39.22  ? 237 ASN B CG  1 
ATOM   2934 O  OD1 . ASN B 2 67  ? -22.492 -2.206  6.242   1   46.7   ? 237 ASN B OD1 1 
ATOM   2935 N  ND2 . ASN B 2 67  ? -24.195 -2.224  4.832   1   49.91  ? 237 ASN B ND2 1 
ATOM   2936 N  N   . TYR B 2 68  ? -20.704 0.846   6.252   1   42.79  ? 238 TYR B N   1 
ATOM   2937 C  CA  . TYR B 2 68  ? -20.333 1.167   7.626   1   40.39  ? 238 TYR B CA  1 
ATOM   2938 C  C   . TYR B 2 68  ? -20.834 2.566   7.972   1   45.41  ? 238 TYR B C   1 
ATOM   2939 O  O   . TYR B 2 68  ? -21.396 2.77    9.054   1   43.61  ? 238 TYR B O   1 
ATOM   2940 C  CB  . TYR B 2 68  ? -18.827 1.078   7.876   1   38.76  ? 238 TYR B CB  1 
ATOM   2941 C  CG  . TYR B 2 68  ? -18.216 -0.294  7.611   1   41.73  ? 238 TYR B CG  1 
ATOM   2942 C  CD1 . TYR B 2 68  ? -19.005 -1.424  7.393   1   38.26  ? 238 TYR B CD1 1 
ATOM   2943 C  CD2 . TYR B 2 68  ? -16.84  -0.445  7.567   1   37.84  ? 238 TYR B CD2 1 
ATOM   2944 C  CE1 . TYR B 2 68  ? -18.44  -2.669  7.149   1   40.66  ? 238 TYR B CE1 1 
ATOM   2945 C  CE2 . TYR B 2 68  ? -16.269 -1.674  7.304   1   41.26  ? 238 TYR B CE2 1 
ATOM   2946 C  CZ  . TYR B 2 68  ? -17.064 -2.79   7.109   1   40.78  ? 238 TYR B CZ  1 
ATOM   2947 O  OH  . TYR B 2 68  ? -16.467 -3.984  6.833   1   42.07  ? 238 TYR B OH  1 
ATOM   2948 N  N   . ILE B 2 69  ? -20.643 3.505   7.022   1   42.92  ? 239 ILE B N   1 
ATOM   2949 C  CA  . ILE B 2 69  ? -20.957 4.905   7.243   1   41.8   ? 239 ILE B CA  1 
ATOM   2950 C  C   . ILE B 2 69  ? -22.456 5.068   7.476   1   45.35  ? 239 ILE B C   1 
ATOM   2951 O  O   . ILE B 2 69  ? -22.849 5.743   8.431   1   45.57  ? 239 ILE B O   1 
ATOM   2952 C  CB  . ILE B 2 69  ? -20.474 5.803   6.093   1   41.16  ? 239 ILE B CB  1 
ATOM   2953 C  CG1 . ILE B 2 69  ? -18.974 5.814   5.986   1   39.84  ? 239 ILE B CG1 1 
ATOM   2954 C  CG2 . ILE B 2 69  ? -21.02  7.226   6.241   1   39.55  ? 239 ILE B CG2 1 
ATOM   2955 C  CD1 . ILE B 2 69  ? -18.491 6.469   4.711   1   36.28  ? 239 ILE B CD1 1 
ATOM   2956 N  N   . ASP B 2 70  ? -23.257 4.453   6.592   1   42.87  ? 240 ASP B N   1 
ATOM   2957 C  CA  . ASP B 2 70  ? -24.703 4.604   6.591   1   43.25  ? 240 ASP B CA  1 
ATOM   2958 C  C   . ASP B 2 70  ? -25.3   3.967   7.842   1   47.47  ? 240 ASP B C   1 
ATOM   2959 O  O   . ASP B 2 70  ? -26.193 4.56    8.441   1   52.72  ? 240 ASP B O   1 
ATOM   2960 C  CB  . ASP B 2 70  ? -25.338 4.025   5.341   1   44.99  ? 240 ASP B CB  1 
ATOM   2961 C  CG  . ASP B 2 70  ? -25.178 4.832   4.062   1   47.51  ? 240 ASP B CG  1 
ATOM   2962 O  OD1 . ASP B 2 70  ? -25.067 6.057   4.173   1   46.17  ? 240 ASP B OD1 1 
ATOM   2963 O  OD2 . ASP B 2 70  ? -25.152 4.219   2.963   1   48.36  ? 240 ASP B OD2 1 
ATOM   2964 N  N   . ARG B 2 71  ? -24.806 2.78    8.232   1   43.51  ? 241 ARG B N   1 
ATOM   2965 C  CA  . ARG B 2 71  ? -25.21  2.16    9.487   1   42.36  ? 241 ARG B CA  1 
ATOM   2966 C  C   . ARG B 2 71  ? -24.848 3.056   10.678  1   45.5   ? 241 ARG B C   1 
ATOM   2967 O  O   . ARG B 2 71  ? -25.662 3.215   11.58   1   44.94  ? 241 ARG B O   1 
ATOM   2968 C  CB  . ARG B 2 71  ? -24.622 0.758   9.653   1   42.1   ? 241 ARG B CB  1 
ATOM   2969 C  CG  . ARG B 2 71  ? -25.386 -0.354  8.942   1   43.34  ? 241 ARG B CG  1 
ATOM   2970 C  CD  . ARG B 2 71  ? -24.48  -1.531  8.57    1   40.59  ? 241 ARG B CD  1 
ATOM   2971 N  NE  . ARG B 2 71  ? -24.207 -2.377  9.73    1   41.35  ? 241 ARG B NE  1 
ATOM   2972 C  CZ  . ARG B 2 71  ? -23.197 -3.224  9.852   1   43.48  ? 241 ARG B CZ  1 
ATOM   2973 N  NH1 . ARG B 2 71  ? -22.297 -3.381  8.89    1   35.78  ? 241 ARG B NH1 1 
ATOM   2974 N  NH2 . ARG B 2 71  ? -23.078 -3.907  10.975  1   48.97  ? 241 ARG B NH2 1 
ATOM   2975 N  N   . PHE B 2 72  ? -23.639 3.647   10.682  1   44.15  ? 242 PHE B N   1 
ATOM   2976 C  CA  . PHE B 2 72  ? -23.211 4.515   11.772  1   45.3   ? 242 PHE B CA  1 
ATOM   2977 C  C   . PHE B 2 72  ? -24.141 5.733   11.891  1   52.47  ? 242 PHE B C   1 
ATOM   2978 O  O   . PHE B 2 72  ? -24.597 6.087   12.985  1   53.43  ? 242 PHE B O   1 
ATOM   2979 C  CB  . PHE B 2 72  ? -21.761 4.951   11.556  1   41.82  ? 242 PHE B CB  1 
ATOM   2980 C  CG  . PHE B 2 72  ? -21.15  5.706   12.729  1   44.7   ? 242 PHE B CG  1 
ATOM   2981 C  CD1 . PHE B 2 72  ? -20.536 5.019   13.765  1   44.66  ? 242 PHE B CD1 1 
ATOM   2982 C  CD2 . PHE B 2 72  ? -21.159 7.103   12.782  1   46.34  ? 242 PHE B CD2 1 
ATOM   2983 C  CE1 . PHE B 2 72  ? -19.972 5.711   14.833  1   48.78  ? 242 PHE B CE1 1 
ATOM   2984 C  CE2 . PHE B 2 72  ? -20.593 7.796   13.846  1   44     ? 242 PHE B CE2 1 
ATOM   2985 C  CZ  . PHE B 2 72  ? -19.99  7.101   14.87   1   47.11  ? 242 PHE B CZ  1 
ATOM   2986 N  N   . LEU B 2 73  ? -24.444 6.368   10.755  1   49.94  ? 243 LEU B N   1 
ATOM   2987 C  CA  . LEU B 2 73  ? -25.23  7.59    10.739  1   54.19  ? 243 LEU B CA  1 
ATOM   2988 C  C   . LEU B 2 73  ? -26.701 7.292   11.005  1   57.7   ? 243 LEU B C   1 
ATOM   2989 O  O   . LEU B 2 73  ? -27.459 8.235   11.227  1   57.31  ? 243 LEU B O   1 
ATOM   2990 C  CB  . LEU B 2 73  ? -25.057 8.303   9.4     1   52.52  ? 243 LEU B CB  1 
ATOM   2991 C  CG  . LEU B 2 73  ? -23.656 8.85    9.126   1   51.69  ? 243 LEU B CG  1 
ATOM   2992 C  CD1 . LEU B 2 73  ? -23.604 9.492   7.761   1   45.27  ? 243 LEU B CD1 1 
ATOM   2993 C  CD2 . LEU B 2 73  ? -23.164 9.769   10.252  1   46.69  ? 243 LEU B CD2 1 
ATOM   2994 N  N   . SER B 2 74  ? -27.076 6       10.973  1   52.36  ? 244 SER B N   1 
ATOM   2995 C  CA  . SER B 2 74  ? -28.402 5.522   11.346  1   52.97  ? 244 SER B CA  1 
ATOM   2996 C  C   . SER B 2 74  ? -28.646 5.605   12.862  1   55.11  ? 244 SER B C   1 
ATOM   2997 O  O   . SER B 2 74  ? -29.79  5.782   13.285  1   57.94  ? 244 SER B O   1 
ATOM   2998 C  CB  . SER B 2 74  ? -28.643 4.125   10.828  1   52.65  ? 244 SER B CB  1 
ATOM   2999 O  OG  . SER B 2 74  ? -28.837 4.105   9.42    1   54.97  ? 244 SER B OG  1 
ATOM   3000 N  N   . SER B 2 75  ? -27.594 5.514   13.705  1   47.76  ? 245 SER B N   1 
ATOM   3001 C  CA  . SER B 2 75  ? -27.844 5.661   15.14   1   52.45  ? 245 SER B CA  1 
ATOM   3002 C  C   . SER B 2 75  ? -27.075 6.806   15.815  1   54.56  ? 245 SER B C   1 
ATOM   3003 O  O   . SER B 2 75  ? -27.363 7.117   16.973  1   57.1   ? 245 SER B O   1 
ATOM   3004 C  CB  . SER B 2 75  ? -27.684 4.377   15.894  1   46.88  ? 245 SER B CB  1 
ATOM   3005 O  OG  . SER B 2 75  ? -26.313 4.038   15.955  1   49.13  ? 245 SER B OG  1 
ATOM   3006 N  N   . MET B 2 76  ? -26.111 7.412   15.101  1   49.35  ? 246 MET B N   1 
ATOM   3007 C  CA  . MET B 2 76  ? -25.229 8.42    15.671  1   49.7   ? 246 MET B CA  1 
ATOM   3008 C  C   . MET B 2 76  ? -25.323 9.71    14.871  1   53.05  ? 246 MET B C   1 
ATOM   3009 O  O   . MET B 2 76  ? -25.16  9.766   13.648  1   57.36  ? 246 MET B O   1 
ATOM   3010 C  CB  . MET B 2 76  ? -23.757 8.007   15.672  1   46.11  ? 246 MET B CB  1 
ATOM   3011 C  CG  . MET B 2 76  ? -23.487 6.696   16.346  1   45.59  ? 246 MET B CG  1 
ATOM   3012 S  SD  . MET B 2 76  ? -23.674 6.827   18.124  1   51.69  ? 246 MET B SD  1 
ATOM   3013 C  CE  . MET B 2 76  ? -22.133 7.553   18.696  1   45.1   ? 246 MET B CE  1 
ATOM   3014 N  N   . SER B 2 77  ? -25.614 10.752  15.622  1   51.48  ? 247 SER B N   1 
ATOM   3015 C  CA  . SER B 2 77  ? -25.842 12.068  15.083  1   51     ? 247 SER B CA  1 
ATOM   3016 C  C   . SER B 2 77  ? -24.46  12.729  14.958  1   52.53  ? 247 SER B C   1 
ATOM   3017 O  O   . SER B 2 77  ? -23.645 12.598  15.868  1   55.34  ? 247 SER B O   1 
ATOM   3018 C  CB  . SER B 2 77  ? -26.815 12.706  16.049  1   45.32  ? 247 SER B CB  1 
ATOM   3019 O  OG  . SER B 2 77  ? -27.09  14.028  15.676  1   55.76  ? 247 SER B OG  1 
ATOM   3020 N  N   . VAL B 2 78  ? -24.131 13.325  13.796  1   52.35  ? 248 VAL B N   1 
ATOM   3021 C  CA  . VAL B 2 78  ? -22.777 13.818  13.518  1   50.51  ? 248 VAL B CA  1 
ATOM   3022 C  C   . VAL B 2 78  ? -22.804 15.246  12.962  1   54.92  ? 248 VAL B C   1 
ATOM   3023 O  O   . VAL B 2 78  ? -23.506 15.5    11.99   1   64.72  ? 248 VAL B O   1 
ATOM   3024 C  CB  . VAL B 2 78  ? -22.056 12.881  12.535  1   48.44  ? 248 VAL B CB  1 
ATOM   3025 C  CG1 . VAL B 2 78  ? -20.655 13.368  12.226  1   48.21  ? 248 VAL B CG1 1 
ATOM   3026 C  CG2 . VAL B 2 78  ? -21.958 11.453  13.07   1   53.5   ? 248 VAL B CG2 1 
ATOM   3027 N  N   . LEU B 2 79  ? -22.016 16.165  13.546  1   53.72  ? 249 LEU B N   1 
ATOM   3028 C  CA  . LEU B 2 79  ? -21.81  17.505  13.001  1   56.52  ? 249 LEU B CA  1 
ATOM   3029 C  C   . LEU B 2 79  ? -21.018 17.463  11.686  1   60.56  ? 249 LEU B C   1 
ATOM   3030 O  O   . LEU B 2 79  ? -20.11  16.639  11.508  1   58.99  ? 249 LEU B O   1 
ATOM   3031 C  CB  . LEU B 2 79  ? -21.112 18.409  14.02   1   56.32  ? 249 LEU B CB  1 
ATOM   3032 C  CG  . LEU B 2 79  ? -21.851 18.684  15.338  1   59.53  ? 249 LEU B CG  1 
ATOM   3033 C  CD1 . LEU B 2 79  ? -21.037 19.632  16.192  1   54.95  ? 249 LEU B CD1 1 
ATOM   3034 C  CD2 . LEU B 2 79  ? -23.267 19.219  15.107  1   60.33  ? 249 LEU B CD2 1 
ATOM   3035 N  N   . ARG B 2 80  ? -21.324 18.407  10.781  1   59.09  ? 250 ARG B N   1 
ATOM   3036 C  CA  . ARG B 2 80  ? -20.766 18.39   9.432   1   57.02  ? 250 ARG B CA  1 
ATOM   3037 C  C   . ARG B 2 80  ? -19.237 18.374  9.482   1   58.59  ? 250 ARG B C   1 
ATOM   3038 O  O   . ARG B 2 80  ? -18.61  17.768  8.612   1   54.88  ? 250 ARG B O   1 
ATOM   3039 C  CB  . ARG B 2 80  ? -21.251 19.581  8.596   1   59.83  ? 250 ARG B CB  1 
ATOM   3040 C  CG  . ARG B 2 80  ? -20.644 20.903  9.049   1   60.24  ? 250 ARG B CG  1 
ATOM   3041 C  CD  . ARG B 2 80  ? -21.317 22.034  8.33    1   64.37  ? 250 ARG B CD  1 
ATOM   3042 N  NE  . ARG B 2 80  ? -22.757 21.983  8.61    1   71.26  ? 250 ARG B NE  1 
ATOM   3043 C  CZ  . ARG B 2 80  ? -23.664 22.816  8.081   1   73.48  ? 250 ARG B CZ  1 
ATOM   3044 N  NH1 . ARG B 2 80  ? -23.321 23.748  7.213   1   67.28  ? 250 ARG B NH1 1 
ATOM   3045 N  NH2 . ARG B 2 80  ? -24.935 22.694  8.409   1   74.78  ? 250 ARG B NH2 1 
ATOM   3046 N  N   . GLY B 2 81  ? -18.647 19.03   10.502  1   55.09  ? 251 GLY B N   1 
ATOM   3047 C  CA  . GLY B 2 81  ? -17.2   19.076  10.673  1   54.21  ? 251 GLY B CA  1 
ATOM   3048 C  C   . GLY B 2 81  ? -16.565 17.717  10.974  1   54.1   ? 251 GLY B C   1 
ATOM   3049 O  O   . GLY B 2 81  ? -15.344 17.577  10.894  1   51.68  ? 251 GLY B O   1 
ATOM   3050 N  N   . LYS B 2 82  ? -17.394 16.723  11.329  1   51.16  ? 252 LYS B N   1 
ATOM   3051 C  CA  . LYS B 2 82  ? -16.888 15.435  11.754  1   47.4   ? 252 LYS B CA  1 
ATOM   3052 C  C   . LYS B 2 82  ? -17.278 14.342  10.77   1   48.44  ? 252 LYS B C   1 
ATOM   3053 O  O   . LYS B 2 82  ? -16.861 13.198  10.943  1   51.75  ? 252 LYS B O   1 
ATOM   3054 C  CB  . LYS B 2 82  ? -17.401 15.1    13.156  1   46.38  ? 252 LYS B CB  1 
ATOM   3055 C  CG  . LYS B 2 82  ? -16.811 15.92   14.307  1   50.69  ? 252 LYS B CG  1 
ATOM   3056 C  CD  . LYS B 2 82  ? -15.286 15.848  14.348  1   54.63  ? 252 LYS B CD  1 
ATOM   3057 C  CE  . LYS B 2 82  ? -14.675 16.142  15.67   1   55.68  ? 252 LYS B CE  1 
ATOM   3058 N  NZ  . LYS B 2 82  ? -14.657 17.594  15.817  1   60.11  ? 252 LYS B NZ  1 
ATOM   3059 N  N   . LEU B 2 83  ? -18.062 14.683  9.741   1   46.42  ? 253 LEU B N   1 
ATOM   3060 C  CA  . LEU B 2 83  ? -18.528 13.674  8.8     1   50.1   ? 253 LEU B CA  1 
ATOM   3061 C  C   . LEU B 2 83  ? -17.352 12.947  8.144   1   52.57  ? 253 LEU B C   1 
ATOM   3062 O  O   . LEU B 2 83  ? -17.368 11.715  8.017   1   55.29  ? 253 LEU B O   1 
ATOM   3063 C  CB  . LEU B 2 83  ? -19.42  14.327  7.746   1   48.37  ? 253 LEU B CB  1 
ATOM   3064 C  CG  . LEU B 2 83  ? -20.064 13.39   6.723   1   46.84  ? 253 LEU B CG  1 
ATOM   3065 C  CD1 . LEU B 2 83  ? -20.797 12.185  7.365   1   41.17  ? 253 LEU B CD1 1 
ATOM   3066 C  CD2 . LEU B 2 83  ? -21.025 14.234  5.92    1   47.22  ? 253 LEU B CD2 1 
ATOM   3067 N  N   . GLN B 2 84  ? -16.338 13.723  7.729   1   52.44  ? 254 GLN B N   1 
ATOM   3068 C  CA  . GLN B 2 84  ? -15.138 13.18   7.101   1   56.64  ? 254 GLN B CA  1 
ATOM   3069 C  C   . GLN B 2 84  ? -14.369 12.226  8.035   1   55.25  ? 254 GLN B C   1 
ATOM   3070 O  O   . GLN B 2 84  ? -13.765 11.248  7.578   1   49.17  ? 254 GLN B O   1 
ATOM   3071 C  CB  . GLN B 2 84  ? -14.242 14.296  6.557   1   55.57  ? 254 GLN B CB  1 
ATOM   3072 C  CG  . GLN B 2 84  ? -13.214 13.788  5.552   1   51.5   ? 254 GLN B CG  1 
ATOM   3073 C  CD  . GLN B 2 84  ? -12.256 14.824  5.001   1   53.99  ? 254 GLN B CD  1 
ATOM   3074 O  OE1 . GLN B 2 84  ? -11.496 14.534  4.074   1   55.58  ? 254 GLN B OE1 1 
ATOM   3075 N  NE2 . GLN B 2 84  ? -12.249 16.027  5.554   1   55.62  ? 254 GLN B NE2 1 
ATOM   3076 N  N   . LEU B 2 85  ? -14.373 12.518  9.344   1   51.79  ? 255 LEU B N   1 
ATOM   3077 C  CA  . LEU B 2 85  ? -13.688 11.675  10.311  1   48.21  ? 255 LEU B CA  1 
ATOM   3078 C  C   . LEU B 2 85  ? -14.334 10.29   10.36   1   48.35  ? 255 LEU B C   1 
ATOM   3079 O  O   . LEU B 2 85  ? -13.616 9.297   10.423  1   48.02  ? 255 LEU B O   1 
ATOM   3080 C  CB  . LEU B 2 85  ? -13.652 12.343  11.683  1   45.32  ? 255 LEU B CB  1 
ATOM   3081 C  CG  . LEU B 2 85  ? -12.96  11.545  12.788  1   47.35  ? 255 LEU B CG  1 
ATOM   3082 C  CD1 . LEU B 2 85  ? -11.561 11.11   12.386  1   47.19  ? 255 LEU B CD1 1 
ATOM   3083 C  CD2 . LEU B 2 85  ? -12.915 12.395  14.044  1   48.12  ? 255 LEU B CD2 1 
ATOM   3084 N  N   . VAL B 2 86  ? -15.676 10.239  10.319  1   45.03  ? 256 VAL B N   1 
ATOM   3085 C  CA  . VAL B 2 86  ? -16.41  8.983   10.289  1   45.18  ? 256 VAL B CA  1 
ATOM   3086 C  C   . VAL B 2 86  ? -16.03  8.204   9.032   1   44.7   ? 256 VAL B C   1 
ATOM   3087 O  O   . VAL B 2 86  ? -15.609 7.049   9.108   1   42.18  ? 256 VAL B O   1 
ATOM   3088 C  CB  . VAL B 2 86  ? -17.932 9.201   10.335  1   47.11  ? 256 VAL B CB  1 
ATOM   3089 C  CG1 . VAL B 2 86  ? -18.67  7.878   10.234  1   41.4   ? 256 VAL B CG1 1 
ATOM   3090 C  CG2 . VAL B 2 86  ? -18.349 9.992   11.566  1   42.79  ? 256 VAL B CG2 1 
ATOM   3091 N  N   . GLY B 2 87  ? -16.174 8.862   7.877   1   43.37  ? 257 GLY B N   1 
ATOM   3092 C  CA  . GLY B 2 87  ? -15.812 8.296   6.589   1   43.25  ? 257 GLY B CA  1 
ATOM   3093 C  C   . GLY B 2 87  ? -14.386 7.742   6.55    1   45.83  ? 257 GLY B C   1 
ATOM   3094 O  O   . GLY B 2 87  ? -14.168 6.662   6.016   1   47.19  ? 257 GLY B O   1 
ATOM   3095 N  N   . THR B 2 88  ? -13.415 8.476   7.108   1   46.02  ? 258 THR B N   1 
ATOM   3096 C  CA  . THR B 2 88  ? -12.019 8.058   7.121   1   43.7   ? 258 THR B CA  1 
ATOM   3097 C  C   . THR B 2 88  ? -11.887 6.772   7.926   1   44.96  ? 258 THR B C   1 
ATOM   3098 O  O   . THR B 2 88  ? -11.206 5.851   7.5     1   45.3   ? 258 THR B O   1 
ATOM   3099 C  CB  . THR B 2 88  ? -11.12  9.154   7.694   1   46.88  ? 258 THR B CB  1 
ATOM   3100 O  OG1 . THR B 2 88  ? -11.368 10.32   6.907   1   55.62  ? 258 THR B OG1 1 
ATOM   3101 C  CG2 . THR B 2 88  ? -9.645  8.789   7.649   1   46.96  ? 258 THR B CG2 1 
ATOM   3102 N  N   . ALA B 2 89  ? -12.517 6.718   9.104   1   46.22  ? 259 ALA B N   1 
ATOM   3103 C  CA  . ALA B 2 89  ? -12.383 5.54    9.955   1   47     ? 259 ALA B CA  1 
ATOM   3104 C  C   . ALA B 2 89  ? -13.1   4.356   9.313   1   43.34  ? 259 ALA B C   1 
ATOM   3105 O  O   . ALA B 2 89  ? -12.636 3.221   9.413   1   41.14  ? 259 ALA B O   1 
ATOM   3106 C  CB  . ALA B 2 89  ? -12.849 5.801   11.372  1   40.74  ? 259 ALA B CB  1 
ATOM   3107 N  N   . ALA B 2 90  ? -14.198 4.656   8.61    1   40.91  ? 260 ALA B N   1 
ATOM   3108 C  CA  . ALA B 2 90  ? -14.923 3.627   7.898   1   43.27  ? 260 ALA B CA  1 
ATOM   3109 C  C   . ALA B 2 90  ? -13.986 2.984   6.877   1   47.67  ? 260 ALA B C   1 
ATOM   3110 O  O   . ALA B 2 90  ? -13.879 1.757   6.821   1   44.98  ? 260 ALA B O   1 
ATOM   3111 C  CB  . ALA B 2 90  ? -16.154 4.216   7.248   1   41.05  ? 260 ALA B CB  1 
ATOM   3112 N  N   . MET B 2 91  ? -13.278 3.826   6.104   1   46.79  ? 261 MET B N   1 
ATOM   3113 C  CA  . MET B 2 91  ? -12.433 3.37    5.007   1   47.59  ? 261 MET B CA  1 
ATOM   3114 C  C   . MET B 2 91  ? -11.255 2.549   5.549   1   48.32  ? 261 MET B C   1 
ATOM   3115 O  O   . MET B 2 91  ? -10.837 1.56    4.932   1   48.91  ? 261 MET B O   1 
ATOM   3116 C  CB  . MET B 2 91  ? -11.94  4.557   4.162   1   46.01  ? 261 MET B CB  1 
ATOM   3117 C  CG  . MET B 2 91  ? -11.404 4.197   2.78    1   52.01  ? 261 MET B CG  1 
ATOM   3118 S  SD  . MET B 2 91  ? -12.675 3.473   1.718   1   58.52  ? 261 MET B SD  1 
ATOM   3119 C  CE  . MET B 2 91  ? -12.088 3.8     0.056   1   57.38  ? 261 MET B CE  1 
ATOM   3120 N  N   . LEU B 2 92  ? -10.733 2.98    6.708   1   42.41  ? 262 LEU B N   1 
ATOM   3121 C  CA  . LEU B 2 92  ? -9.646  2.291   7.371   1   42.38  ? 262 LEU B CA  1 
ATOM   3122 C  C   . LEU B 2 92  ? -10.109 0.886   7.772   1   46.3   ? 262 LEU B C   1 
ATOM   3123 O  O   . LEU B 2 92  ? -9.426  -0.102  7.477   1   51.15  ? 262 LEU B O   1 
ATOM   3124 C  CB  . LEU B 2 92  ? -9.191  3.133   8.565   1   43.93  ? 262 LEU B CB  1 
ATOM   3125 C  CG  . LEU B 2 92  ? -8.17   2.499   9.528   1   44.71  ? 262 LEU B CG  1 
ATOM   3126 C  CD1 . LEU B 2 92  ? -6.863  2.185   8.833   1   45.28  ? 262 LEU B CD1 1 
ATOM   3127 C  CD2 . LEU B 2 92  ? -7.888  3.379   10.721  1   44.25  ? 262 LEU B CD2 1 
ATOM   3128 N  N   . LEU B 2 93  ? -11.277 0.805   8.422   1   40.62  ? 263 LEU B N   1 
ATOM   3129 C  CA  . LEU B 2 93  ? -11.809 -0.471  8.874   1   43.37  ? 263 LEU B CA  1 
ATOM   3130 C  C   . LEU B 2 93  ? -12.046 -1.391  7.676   1   42.02  ? 263 LEU B C   1 
ATOM   3131 O  O   . LEU B 2 93  ? -11.7   -2.57   7.707   1   47.33  ? 263 LEU B O   1 
ATOM   3132 C  CB  . LEU B 2 93  ? -13.087 -0.263  9.692   1   44.86  ? 263 LEU B CB  1 
ATOM   3133 C  CG  . LEU B 2 93  ? -12.937 0.212   11.145  1   44.74  ? 263 LEU B CG  1 
ATOM   3134 C  CD1 . LEU B 2 93  ? -14.325 0.501   11.714  1   42.72  ? 263 LEU B CD1 1 
ATOM   3135 C  CD2 . LEU B 2 93  ? -12.257 -0.849  12.022  1   46.52  ? 263 LEU B CD2 1 
ATOM   3136 N  N   . ALA B 2 94  ? -12.644 -0.851  6.613   1   42.79  ? 264 ALA B N   1 
ATOM   3137 C  CA  . ALA B 2 94  ? -12.959 -1.631  5.417   1   39.72  ? 264 ALA B CA  1 
ATOM   3138 C  C   . ALA B 2 94  ? -11.678 -2.126  4.755   1   42.16  ? 264 ALA B C   1 
ATOM   3139 O  O   . ALA B 2 94  ? -11.625 -3.276  4.326   1   45.17  ? 264 ALA B O   1 
ATOM   3140 C  CB  . ALA B 2 94  ? -13.761 -0.813  4.445   1   37.08  ? 264 ALA B CB  1 
ATOM   3141 N  N   . SER B 2 95  ? -10.656 -1.258  4.692   1   41.23  ? 265 SER B N   1 
ATOM   3142 C  CA  . SER B 2 95  ? -9.332  -1.629  4.211   1   41.1   ? 265 SER B CA  1 
ATOM   3143 C  C   . SER B 2 95  ? -8.735  -2.787  5.027   1   44.29  ? 265 SER B C   1 
ATOM   3144 O  O   . SER B 2 95  ? -8.269  -3.764  4.444   1   45.56  ? 265 SER B O   1 
ATOM   3145 C  CB  . SER B 2 95  ? -8.42   -0.435  4.192   1   41.3   ? 265 SER B CB  1 
ATOM   3146 O  OG  . SER B 2 95  ? -8.962  0.577   3.361   1   45.51  ? 265 SER B OG  1 
ATOM   3147 N  N   . LYS B 2 96  ? -8.726  -2.69   6.368   1   40.01  ? 266 LYS B N   1 
ATOM   3148 C  CA  . LYS B 2 96  ? -8.192  -3.771  7.194   1   41.69  ? 266 LYS B CA  1 
ATOM   3149 C  C   . LYS B 2 96  ? -8.998  -5.061  6.987   1   44.22  ? 266 LYS B C   1 
ATOM   3150 O  O   . LYS B 2 96  ? -8.452  -6.158  7.057   1   45.61  ? 266 LYS B O   1 
ATOM   3151 C  CB  . LYS B 2 96  ? -8.187  -3.399  8.678   1   37.82  ? 266 LYS B CB  1 
ATOM   3152 C  CG  . LYS B 2 96  ? -7.153  -2.369  9.095   1   40.6   ? 266 LYS B CG  1 
ATOM   3153 C  CD  . LYS B 2 96  ? -7.42   -1.834  10.487  1   36.87  ? 266 LYS B CD  1 
ATOM   3154 C  CE  . LYS B 2 96  ? -6.371  -0.948  11.045  1   42.13  ? 266 LYS B CE  1 
ATOM   3155 N  NZ  . LYS B 2 96  ? -6.64   -0.651  12.464  1   41.89  ? 266 LYS B NZ  1 
ATOM   3156 N  N   . PHE B 2 97  ? -10.292 -4.949  6.688   1   39.78  ? 267 PHE B N   1 
ATOM   3157 C  CA  . PHE B 2 97  ? -11.081 -6.15   6.497   1   41.42  ? 267 PHE B CA  1 
ATOM   3158 C  C   . PHE B 2 97  ? -10.749 -6.818  5.174   1   41.45  ? 267 PHE B C   1 
ATOM   3159 O  O   . PHE B 2 97  ? -10.528 -8.035  5.124   1   42.31  ? 267 PHE B O   1 
ATOM   3160 C  CB  . PHE B 2 97  ? -12.57  -5.81   6.448   1   42.01  ? 267 PHE B CB  1 
ATOM   3161 C  CG  . PHE B 2 97  ? -13.475 -7.036  6.44    1   42.01  ? 267 PHE B CG  1 
ATOM   3162 C  CD1 . PHE B 2 97  ? -13.763 -7.717  7.618   1   40.48  ? 267 PHE B CD1 1 
ATOM   3163 C  CD2 . PHE B 2 97  ? -14.074 -7.476  5.261   1   40.88  ? 267 PHE B CD2 1 
ATOM   3164 C  CE1 . PHE B 2 97  ? -14.6   -8.822  7.597   1   43.38  ? 267 PHE B CE1 1 
ATOM   3165 C  CE2 . PHE B 2 97  ? -14.919 -8.58   5.247   1   39.68  ? 267 PHE B CE2 1 
ATOM   3166 C  CZ  . PHE B 2 97  ? -15.173 -9.255  6.415   1   42.9   ? 267 PHE B CZ  1 
ATOM   3167 N  N   . GLU B 2 98  ? -10.827 -6.052  4.084   1   40.31  ? 268 GLU B N   1 
ATOM   3168 C  CA  . GLU B 2 98  ? -10.773 -6.648  2.724   1   43.01  ? 268 GLU B CA  1 
ATOM   3169 C  C   . GLU B 2 98  ? -9.422  -6.586  2.003   1   45.87  ? 268 GLU B C   1 
ATOM   3170 O  O   . GLU B 2 98  ? -9.218  -7.409  1.103   1   49.28  ? 268 GLU B O   1 
ATOM   3171 C  CB  . GLU B 2 98  ? -11.815 -5.853  1.938   1   38.47  ? 268 GLU B CB  1 
ATOM   3172 C  CG  . GLU B 2 98  ? -12.241 -6.494  0.624   1   44.85  ? 268 GLU B CG  1 
ATOM   3173 C  CD  . GLU B 2 98  ? -12.867 -7.857  0.819   1   48.48  ? 268 GLU B CD  1 
ATOM   3174 O  OE1 . GLU B 2 98  ? -13.638 -8.024  1.78    1   49.23  ? 268 GLU B OE1 1 
ATOM   3175 O  OE2 . GLU B 2 98  ? -12.578 -8.751  0.008   1   46.93  ? 268 GLU B OE2 1 
ATOM   3176 N  N   . GLU B 2 99  ? -8.547  -5.658  2.355   1   43.7   ? 269 GLU B N   1 
ATOM   3177 C  CA  . GLU B 2 99  ? -7.301  -5.525  1.611   1   46.23  ? 269 GLU B CA  1 
ATOM   3178 C  C   . GLU B 2 99  ? -6.202  -6.475  2.095   1   51.35  ? 269 GLU B C   1 
ATOM   3179 O  O   . GLU B 2 99  ? -5.999  -6.658  3.298   1   48.62  ? 269 GLU B O   1 
ATOM   3180 C  CB  . GLU B 2 99  ? -6.81   -4.083  1.673   1   42.88  ? 269 GLU B CB  1 
ATOM   3181 C  CG  . GLU B 2 99  ? -7.815  -3.124  1.036   1   47.65  ? 269 GLU B CG  1 
ATOM   3182 C  CD  . GLU B 2 99  ? -7.857  -3.111  -0.486  1   49.6   ? 269 GLU B CD  1 
ATOM   3183 O  OE1 . GLU B 2 99  ? -6.798  -3.44   -1.109  1   49.37  ? 269 GLU B OE1 1 
ATOM   3184 O  OE2 . GLU B 2 99  ? -8.951  -2.805  -1.04   1   46.81  ? 269 GLU B OE2 1 
ATOM   3185 N  N   . ILE B 2 100 ? -5.454  -7.019  1.121   1   46.2   ? 270 ILE B N   1 
ATOM   3186 C  CA  . ILE B 2 100 ? -4.205  -7.713  1.373   1   46.21  ? 270 ILE B CA  1 
ATOM   3187 C  C   . ILE B 2 100 ? -3.234  -6.734  2.039   1   50.41  ? 270 ILE B C   1 
ATOM   3188 O  O   . ILE B 2 100 ? -2.612  -7.077  3.038   1   54.17  ? 270 ILE B O   1 
ATOM   3189 C  CB  . ILE B 2 100 ? -3.63   -8.299  0.058   1   46.95  ? 270 ILE B CB  1 
ATOM   3190 C  CG1 . ILE B 2 100 ? -4.555  -9.32   -0.62   1   45.15  ? 270 ILE B CG1 1 
ATOM   3191 C  CG2 . ILE B 2 100 ? -2.249  -8.909  0.26    1   40.09  ? 270 ILE B CG2 1 
ATOM   3192 C  CD1 . ILE B 2 100 ? -4.169  -9.65   -2.054  1   40.91  ? 270 ILE B CD1 1 
ATOM   3193 N  N   . TYR B 2 101 ? -3.085  -5.535  1.451   1   50.71  ? 271 TYR B N   1 
ATOM   3194 C  CA  . TYR B 2 101 ? -2.15   -4.513  1.908   1   56.58  ? 271 TYR B CA  1 
ATOM   3195 C  C   . TYR B 2 101 ? -2.883  -3.194  2.189   1   56.22  ? 271 TYR B C   1 
ATOM   3196 O  O   . TYR B 2 101 ? -2.905  -2.281  1.366   1   56.84  ? 271 TYR B O   1 
ATOM   3197 C  CB  . TYR B 2 101 ? -0.984  -4.296  0.926   1   58.05  ? 271 TYR B CB  1 
ATOM   3198 C  CG  . TYR B 2 101 ? -0.129  -5.52   0.619   1   60.52  ? 271 TYR B CG  1 
ATOM   3199 C  CD1 . TYR B 2 101 ? 0.716   -6.079  1.585   1   62.33  ? 271 TYR B CD1 1 
ATOM   3200 C  CD2 . TYR B 2 101 ? -0.171  -6.119  -0.641  1   61.49  ? 271 TYR B CD2 1 
ATOM   3201 C  CE1 . TYR B 2 101 ? 1.487   -7.205  1.311   1   62.91  ? 271 TYR B CE1 1 
ATOM   3202 C  CE2 . TYR B 2 101 ? 0.592   -7.24   -0.927  1   64.08  ? 271 TYR B CE2 1 
ATOM   3203 C  CZ  . TYR B 2 101 ? 1.415   -7.784  0.049   1   65.91  ? 271 TYR B CZ  1 
ATOM   3204 O  OH  . TYR B 2 101 ? 2.126   -8.892  -0.301  1   74.1   ? 271 TYR B OH  1 
ATOM   3205 N  N   . PRO B 2 102 ? -3.52   -3.03   3.367   1   54.43  ? 272 PRO B N   1 
ATOM   3206 C  CA  . PRO B 2 102 ? -4.237  -1.792  3.666   1   50.39  ? 272 PRO B CA  1 
ATOM   3207 C  C   . PRO B 2 102 ? -3.256  -0.636  3.786   1   50.07  ? 272 PRO B C   1 
ATOM   3208 O  O   . PRO B 2 102 ? -2.109  -0.823  4.178   1   52.91  ? 272 PRO B O   1 
ATOM   3209 C  CB  . PRO B 2 102 ? -4.974  -2.057  4.983   1   47.86  ? 272 PRO B CB  1 
ATOM   3210 C  CG  . PRO B 2 102 ? -4.288  -3.271  5.564   1   48.66  ? 272 PRO B CG  1 
ATOM   3211 C  CD  . PRO B 2 102 ? -3.587  -4.023  4.45    1   49.41  ? 272 PRO B CD  1 
ATOM   3212 N  N   . PRO B 2 103 ? -3.673  0.595   3.435   1   51.05  ? 273 PRO B N   1 
ATOM   3213 C  CA  . PRO B 2 103 ? -2.856  1.777   3.718   1   53.1   ? 273 PRO B CA  1 
ATOM   3214 C  C   . PRO B 2 103 ? -2.704  1.89    5.231   1   55.89  ? 273 PRO B C   1 
ATOM   3215 O  O   . PRO B 2 103 ? -3.558  1.46    6.005   1   55.38  ? 273 PRO B O   1 
ATOM   3216 C  CB  . PRO B 2 103 ? -3.666  2.935   3.12    1   53.96  ? 273 PRO B CB  1 
ATOM   3217 C  CG  . PRO B 2 103 ? -4.655  2.277   2.157   1   50.15  ? 273 PRO B CG  1 
ATOM   3218 C  CD  . PRO B 2 103 ? -4.927  0.904   2.731   1   47.43  ? 273 PRO B CD  1 
ATOM   3219 N  N   . GLU B 2 104 ? -1.579  2.453   5.659   1   63.31  ? 274 GLU B N   1 
ATOM   3220 C  CA  . GLU B 2 104 ? -1.327  2.643   7.077   1   62.27  ? 274 GLU B CA  1 
ATOM   3221 C  C   . GLU B 2 104 ? -2.18   3.798   7.591   1   64.33  ? 274 GLU B C   1 
ATOM   3222 O  O   . GLU B 2 104 ? -2.642  4.644   6.825   1   64.72  ? 274 GLU B O   1 
ATOM   3223 C  CB  . GLU B 2 104 ? 0.146   2.97    7.277   1   67.21  ? 274 GLU B CB  1 
ATOM   3224 C  CG  . GLU B 2 104 ? 1.057   1.868   6.753   1   79.31  ? 274 GLU B CG  1 
ATOM   3225 C  CD  . GLU B 2 104 ? 2.532   2.164   6.924   1   99.19  ? 274 GLU B CD  1 
ATOM   3226 O  OE1 . GLU B 2 104 ? 3.189   1.349   7.609   1   108.15 ? 274 GLU B OE1 1 
ATOM   3227 O  OE2 . GLU B 2 104 ? 3.013   3.192   6.385   1   108.45 ? 274 GLU B OE2 1 
ATOM   3228 N  N   . VAL B 2 105 ? -2.388  3.82    8.907   1   60.14  ? 275 VAL B N   1 
ATOM   3229 C  CA  . VAL B 2 105 ? -3.208  4.85    9.521   1   61.09  ? 275 VAL B CA  1 
ATOM   3230 C  C   . VAL B 2 105 ? -2.726  6.231   9.066   1   60.58  ? 275 VAL B C   1 
ATOM   3231 O  O   . VAL B 2 105 ? -3.536  7.054   8.66    1   61.07  ? 275 VAL B O   1 
ATOM   3232 C  CB  . VAL B 2 105 ? -3.196  4.663   11.05   1   63.64  ? 275 VAL B CB  1 
ATOM   3233 C  CG1 . VAL B 2 105 ? -3.793  5.835   11.816  1   61.81  ? 275 VAL B CG1 1 
ATOM   3234 C  CG2 . VAL B 2 105 ? -3.906  3.374   11.424  1   62.67  ? 275 VAL B CG2 1 
ATOM   3235 N  N   . ALA B 2 106 ? -1.407  6.449   9.068   1   56.98  ? 276 ALA B N   1 
ATOM   3236 C  CA  . ALA B 2 106 ? -0.848  7.752   8.765   1   57.9   ? 276 ALA B CA  1 
ATOM   3237 C  C   . ALA B 2 106 ? -1.29   8.22    7.379   1   59.33  ? 276 ALA B C   1 
ATOM   3238 O  O   . ALA B 2 106 ? -1.549  9.4     7.199   1   65.1   ? 276 ALA B O   1 
ATOM   3239 C  CB  . ALA B 2 106 ? 0.646   7.714   8.908   1   55.58  ? 276 ALA B CB  1 
ATOM   3240 N  N   . GLU B 2 107 ? -1.423  7.294   6.419   1   57.25  ? 277 GLU B N   1 
ATOM   3241 C  CA  . GLU B 2 107 ? -1.875  7.665   5.091   1   59.08  ? 277 GLU B CA  1 
ATOM   3242 C  C   . GLU B 2 107 ? -3.319  8.159   5.151   1   57.36  ? 277 GLU B C   1 
ATOM   3243 O  O   . GLU B 2 107 ? -3.682  9.102   4.458   1   59.79  ? 277 GLU B O   1 
ATOM   3244 C  CB  . GLU B 2 107 ? -1.668  6.524   4.1     1   63.11  ? 277 GLU B CB  1 
ATOM   3245 C  CG  . GLU B 2 107 ? -0.202  6.317   3.739   1   77.29  ? 277 GLU B CG  1 
ATOM   3246 C  CD  . GLU B 2 107 ? 0.076   5.049   2.945   1   100.45 ? 277 GLU B CD  1 
ATOM   3247 O  OE1 . GLU B 2 107 ? 0.525   5.227   1.786   1   111.35 ? 277 GLU B OE1 1 
ATOM   3248 O  OE2 . GLU B 2 107 ? -0.141  3.909   3.458   1   96.39  ? 277 GLU B OE2 1 
ATOM   3249 N  N   . PHE B 2 108 ? -4.143  7.522   5.985   1   54.95  ? 278 PHE B N   1 
ATOM   3250 C  CA  . PHE B 2 108 ? -5.512  7.975   6.178   1   53.28  ? 278 PHE B CA  1 
ATOM   3251 C  C   . PHE B 2 108 ? -5.544  9.385   6.779   1   57.17  ? 278 PHE B C   1 
ATOM   3252 O  O   . PHE B 2 108 ? -6.393  10.179  6.388   1   62.7   ? 278 PHE B O   1 
ATOM   3253 C  CB  . PHE B 2 108 ? -6.322  6.924   6.941   1   48.67  ? 278 PHE B CB  1 
ATOM   3254 C  CG  . PHE B 2 108 ? -6.73   5.762   6.055   1   49.3   ? 278 PHE B CG  1 
ATOM   3255 C  CD1 . PHE B 2 108 ? -7.781  5.894   5.156   1   49.71  ? 278 PHE B CD1 1 
ATOM   3256 C  CD2 . PHE B 2 108 ? -6.042  4.553   6.092   1   52.95  ? 278 PHE B CD2 1 
ATOM   3257 C  CE1 . PHE B 2 108 ? -8.13   4.836   4.33    1   50.03  ? 278 PHE B CE1 1 
ATOM   3258 C  CE2 . PHE B 2 108 ? -6.403  3.497   5.26    1   50.14  ? 278 PHE B CE2 1 
ATOM   3259 C  CZ  . PHE B 2 108 ? -7.454  3.634   4.392   1   48.08  ? 278 PHE B CZ  1 
ATOM   3260 N  N   . VAL B 2 109 ? -4.619  9.705   7.703   1   54.04  ? 279 VAL B N   1 
ATOM   3261 C  CA  . VAL B 2 109 ? -4.52   11.043  8.263   1   55.95  ? 279 VAL B CA  1 
ATOM   3262 C  C   . VAL B 2 109 ? -4.136  12.014  7.153   1   61.35  ? 279 VAL B C   1 
ATOM   3263 O  O   . VAL B 2 109 ? -4.69   13.107  7.084   1   64.7   ? 279 VAL B O   1 
ATOM   3264 C  CB  . VAL B 2 109 ? -3.516  11.139  9.433   1   59.53  ? 279 VAL B CB  1 
ATOM   3265 C  CG1 . VAL B 2 109 ? -3.204  12.581  9.822   1   56.96  ? 279 VAL B CG1 1 
ATOM   3266 C  CG2 . VAL B 2 109 ? -3.963  10.352  10.659  1   56.4   ? 279 VAL B CG2 1 
ATOM   3267 N  N   . TYR B 2 110 ? -3.184  11.596  6.308   1   65.24  ? 280 TYR B N   1 
ATOM   3268 C  CA  . TYR B 2 110 ? -2.617  12.415  5.247   1   73.79  ? 280 TYR B CA  1 
ATOM   3269 C  C   . TYR B 2 110 ? -3.689  12.877  4.253   1   72.58  ? 280 TYR B C   1 
ATOM   3270 O  O   . TYR B 2 110 ? -3.689  14.042  3.854   1   83.33  ? 280 TYR B O   1 
ATOM   3271 C  CB  . TYR B 2 110 ? -1.415  11.728  4.586   1   79.74  ? 280 TYR B CB  1 
ATOM   3272 C  CG  . TYR B 2 110 ? -0.827  12.515  3.421   1   93.11  ? 280 TYR B CG  1 
ATOM   3273 C  CD1 . TYR B 2 110 ? -0.119  13.695  3.651   1   104.56 ? 280 TYR B CD1 1 
ATOM   3274 C  CD2 . TYR B 2 110 ? -0.989  12.098  2.097   1   94     ? 280 TYR B CD2 1 
ATOM   3275 C  CE1 . TYR B 2 110 ? 0.405   14.438  2.604   1   103.83 ? 280 TYR B CE1 1 
ATOM   3276 C  CE2 . TYR B 2 110 ? -0.462  12.83   1.041   1   95.72  ? 280 TYR B CE2 1 
ATOM   3277 C  CZ  . TYR B 2 110 ? 0.241   14      1.298   1   101.34 ? 280 TYR B CZ  1 
ATOM   3278 O  OH  . TYR B 2 110 ? 0.768   14.752  0.286   1   97.84  ? 280 TYR B OH  1 
ATOM   3279 N  N   . ILE B 2 111 ? -4.607  11.986  3.861   1   65.98  ? 281 ILE B N   1 
ATOM   3280 C  CA  . ILE B 2 111 ? -5.594  12.302  2.835   1   65.38  ? 281 ILE B CA  1 
ATOM   3281 C  C   . ILE B 2 111 ? -6.673  13.259  3.34    1   64.92  ? 281 ILE B C   1 
ATOM   3282 O  O   . ILE B 2 111 ? -7.419  13.81   2.529   1   67.02  ? 281 ILE B O   1 
ATOM   3283 C  CB  . ILE B 2 111 ? -6.236  11.039  2.246   1   66.94  ? 281 ILE B CB  1 
ATOM   3284 C  CG1 . ILE B 2 111 ? -6.796  10.155  3.353   1   66.63  ? 281 ILE B CG1 1 
ATOM   3285 C  CG2 . ILE B 2 111 ? -5.246  10.303  1.348   1   68.09  ? 281 ILE B CG2 1 
ATOM   3286 C  CD1 . ILE B 2 111 ? -7.994  9.313   2.941   1   69.37  ? 281 ILE B CD1 1 
ATOM   3287 N  N   . THR B 2 112 ? -6.768  13.424  4.666   1   66.12  ? 282 THR B N   1 
ATOM   3288 C  CA  . THR B 2 112 ? -7.709  14.354  5.281   1   66.11  ? 282 THR B CA  1 
ATOM   3289 C  C   . THR B 2 112 ? -7.148  15.773  5.367   1   74.8   ? 282 THR B C   1 
ATOM   3290 O  O   . THR B 2 112 ? -7.827  16.618  5.941   1   72.84  ? 282 THR B O   1 
ATOM   3291 C  CB  . THR B 2 112 ? -8.155  13.878  6.662   1   63     ? 282 THR B CB  1 
ATOM   3292 O  OG1 . THR B 2 112 ? -7.016  13.952  7.511   1   71.09  ? 282 THR B OG1 1 
ATOM   3293 C  CG2 . THR B 2 112 ? -8.769  12.49   6.639   1   53.02  ? 282 THR B CG2 1 
ATOM   3294 N  N   . ASP B 2 113 ? -5.939  16.016  4.81    1   94.28  ? 283 ASP B N   1 
ATOM   3295 C  CA  . ASP B 2 113 ? -5.233  17.298  4.759   1   100.75 ? 283 ASP B CA  1 
ATOM   3296 C  C   . ASP B 2 113 ? -5.03   17.855  6.161   1   105.27 ? 283 ASP B C   1 
ATOM   3297 O  O   . ASP B 2 113 ? -5.21   19.048  6.397   1   101.07 ? 283 ASP B O   1 
ATOM   3298 C  CB  . ASP B 2 113 ? -5.913  18.298  3.837   1   107.61 ? 283 ASP B CB  1 
ATOM   3299 C  CG  . ASP B 2 113 ? -6.111  17.794  2.419   1   114.36 ? 283 ASP B CG  1 
ATOM   3300 O  OD1 . ASP B 2 113 ? -5.691  16.645  2.142   1   114.57 ? 283 ASP B OD1 1 
ATOM   3301 O  OD2 . ASP B 2 113 ? -6.67   18.559  1.614   1   120.55 ? 283 ASP B OD2 1 
ATOM   3302 N  N   . ASP B 2 114 ? -4.677  16.955  7.083   1   116.37 ? 284 ASP B N   1 
ATOM   3303 C  CA  . ASP B 2 114 ? -4.404  17.291  8.471   1   117.5  ? 284 ASP B CA  1 
ATOM   3304 C  C   . ASP B 2 114 ? -5.592  18.023  9.107   1   99.64  ? 284 ASP B C   1 
ATOM   3305 O  O   . ASP B 2 114 ? -5.411  18.84   10.011  1   83.77  ? 284 ASP B O   1 
ATOM   3306 C  CB  . ASP B 2 114 ? -3.027  17.924  8.6     1   138.88 ? 284 ASP B CB  1 
ATOM   3307 C  CG  . ASP B 2 114 ? -1.858  17.108  8.056   1   140.7  ? 284 ASP B CG  1 
ATOM   3308 O  OD1 . ASP B 2 114 ? -1.99   15.872  7.924   1   134.45 ? 284 ASP B OD1 1 
ATOM   3309 O  OD2 . ASP B 2 114 ? -0.824  17.723  7.732   1   149.49 ? 284 ASP B OD2 1 
ATOM   3310 N  N   . THR B 2 115 ? -6.815  17.676  8.668   1   94.52  ? 285 THR B N   1 
ATOM   3311 C  CA  . THR B 2 115 ? -8.054  18.114  9.309   1   89.06  ? 285 THR B CA  1 
ATOM   3312 C  C   . THR B 2 115 ? -8.2    17.424  10.671  1   81.04  ? 285 THR B C   1 
ATOM   3313 O  O   . THR B 2 115 ? -8.839  17.932  11.59   1   81.42  ? 285 THR B O   1 
ATOM   3314 C  CB  . THR B 2 115 ? -9.256  17.81   8.408   1   78.14  ? 285 THR B CB  1 
ATOM   3315 O  OG1 . THR B 2 115 ? -9.083  18.529  7.2     1   85.77  ? 285 THR B OG1 1 
ATOM   3316 C  CG2 . THR B 2 115 ? -10.57  18.316  8.976   1   77.41  ? 285 THR B CG2 1 
ATOM   3317 N  N   . TYR B 2 116 ? -7.612  16.235  10.778  1   73.28  ? 286 TYR B N   1 
ATOM   3318 C  CA  . TYR B 2 116 ? -7.777  15.396  11.947  1   67.32  ? 286 TYR B CA  1 
ATOM   3319 C  C   . TYR B 2 116 ? -6.415  14.823  12.303  1   65.02  ? 286 TYR B C   1 
ATOM   3320 O  O   . TYR B 2 116 ? -5.505  14.82   11.483  1   74.24  ? 286 TYR B O   1 
ATOM   3321 C  CB  . TYR B 2 116 ? -8.751  14.256  11.641  1   59.71  ? 286 TYR B CB  1 
ATOM   3322 C  CG  . TYR B 2 116 ? -10.119 14.671  11.121  1   60.88  ? 286 TYR B CG  1 
ATOM   3323 C  CD1 . TYR B 2 116 ? -11.022 15.373  11.928  1   58.57  ? 286 TYR B CD1 1 
ATOM   3324 C  CD2 . TYR B 2 116 ? -10.536 14.302  9.842   1   62.38  ? 286 TYR B CD2 1 
ATOM   3325 C  CE1 . TYR B 2 116 ? -12.279 15.74   11.47   1   52.57  ? 286 TYR B CE1 1 
ATOM   3326 C  CE2 . TYR B 2 116 ? -11.796 14.66   9.375   1   61.48  ? 286 TYR B CE2 1 
ATOM   3327 C  CZ  . TYR B 2 116 ? -12.666 15.375  10.194  1   55.85  ? 286 TYR B CZ  1 
ATOM   3328 O  OH  . TYR B 2 116 ? -13.921 15.683  9.772   1   58.88  ? 286 TYR B OH  1 
ATOM   3329 N  N   . THR B 2 117 ? -6.286  14.374  13.549  1   64.39  ? 287 THR B N   1 
ATOM   3330 C  CA  . THR B 2 117 ? -5.054  13.794  14.056  1   65.32  ? 287 THR B CA  1 
ATOM   3331 C  C   . THR B 2 117 ? -5.153  12.276  13.981  1   62.82  ? 287 THR B C   1 
ATOM   3332 O  O   . THR B 2 117 ? -6.248  11.726  13.874  1   58.67  ? 287 THR B O   1 
ATOM   3333 C  CB  . THR B 2 117 ? -4.816  14.231  15.5    1   63.61  ? 287 THR B CB  1 
ATOM   3334 O  OG1 . THR B 2 117 ? -5.926  13.784  16.28   1   62.61  ? 287 THR B OG1 1 
ATOM   3335 C  CG2 . THR B 2 117 ? -4.612  15.73   15.586  1   58.52  ? 287 THR B CG2 1 
ATOM   3336 N  N   . LYS B 2 118 ? -4.002  11.606  14.086  1   60.71  ? 288 LYS B N   1 
ATOM   3337 C  CA  . LYS B 2 118 ? -4.006  10.155  14.105  1   62.33  ? 288 LYS B CA  1 
ATOM   3338 C  C   . LYS B 2 118 ? -4.806  9.631   15.298  1   57.07  ? 288 LYS B C   1 
ATOM   3339 O  O   . LYS B 2 118 ? -5.444  8.585   15.198  1   58.18  ? 288 LYS B O   1 
ATOM   3340 C  CB  . LYS B 2 118 ? -2.566  9.651   13.957  1   66.63  ? 288 LYS B CB  1 
ATOM   3341 C  CG  . LYS B 2 118 ? -2.262  8.241   14.381  1   68.05  ? 288 LYS B CG  1 
ATOM   3342 C  CD  . LYS B 2 118 ? -0.821  7.874   14.009  1   74.55  ? 288 LYS B CD  1 
ATOM   3343 C  CE  . LYS B 2 118 ? -0.506  6.395   14.018  1   85.85  ? 288 LYS B CE  1 
ATOM   3344 N  NZ  . LYS B 2 118 ? 0.004   5.774   15.257  1   92.1   ? 288 LYS B NZ  1 
ATOM   3345 N  N   . LYS B 2 119 ? -4.771  10.358  16.419  1   58.43  ? 289 LYS B N   1 
ATOM   3346 C  CA  . LYS B 2 119 ? -5.486  9.963   17.63   1   63.69  ? 289 LYS B CA  1 
ATOM   3347 C  C   . LYS B 2 119 ? -6.994  9.988   17.397  1   60.97  ? 289 LYS B C   1 
ATOM   3348 O  O   . LYS B 2 119 ? -7.682  9.055   17.815  1   58.27  ? 289 LYS B O   1 
ATOM   3349 C  CB  . LYS B 2 119 ? -5.096  10.863  18.805  1   73.55  ? 289 LYS B CB  1 
ATOM   3350 C  CG  . LYS B 2 119 ? -5.662  10.544  20.169  1   87.06  ? 289 LYS B CG  1 
ATOM   3351 C  CD  . LYS B 2 119 ? -4.891  11.288  21.253  1   102.26 ? 289 LYS B CD  1 
ATOM   3352 C  CE  . LYS B 2 119 ? -5.779  12.019  22.221  1   107.64 ? 289 LYS B CE  1 
ATOM   3353 N  NZ  . LYS B 2 119 ? -6.738  11.145  22.904  1   106.27 ? 289 LYS B NZ  1 
ATOM   3354 N  N   . GLN B 2 120 ? -7.477  11.058  16.734  1   58.2   ? 290 GLN B N   1 
ATOM   3355 C  CA  . GLN B 2 120 ? -8.881  11.201  16.364  1   57.44  ? 290 GLN B CA  1 
ATOM   3356 C  C   . GLN B 2 120 ? -9.321  10.086  15.402  1   58.02  ? 290 GLN B C   1 
ATOM   3357 O  O   . GLN B 2 120 ? -10.458 9.611   15.486  1   59.33  ? 290 GLN B O   1 
ATOM   3358 C  CB  . GLN B 2 120 ? -9.187  12.54   15.692  1   53.92  ? 290 GLN B CB  1 
ATOM   3359 C  CG  . GLN B 2 120 ? -9.238  13.747  16.614  1   58.38  ? 290 GLN B CG  1 
ATOM   3360 C  CD  . GLN B 2 120 ? -9.474  15.034  15.843  1   66.21  ? 290 GLN B CD  1 
ATOM   3361 O  OE1 . GLN B 2 120 ? -8.685  15.428  14.972  1   63.53  ? 290 GLN B OE1 1 
ATOM   3362 N  NE2 . GLN B 2 120 ? -10.582 15.699  16.148  1   59.81  ? 290 GLN B NE2 1 
ATOM   3363 N  N   . VAL B 2 121 ? -8.456  9.71    14.444  1   52.99  ? 291 VAL B N   1 
ATOM   3364 C  CA  . VAL B 2 121 ? -8.822  8.65    13.518  1   53.99  ? 291 VAL B CA  1 
ATOM   3365 C  C   . VAL B 2 121 ? -8.924  7.315   14.264  1   54.05  ? 291 VAL B C   1 
ATOM   3366 O  O   . VAL B 2 121 ? -9.834  6.529   14.016  1   50.69  ? 291 VAL B O   1 
ATOM   3367 C  CB  . VAL B 2 121 ? -7.812  8.56    12.365  1   54.84  ? 291 VAL B CB  1 
ATOM   3368 C  CG1 . VAL B 2 121 ? -8.051  7.325   11.492  1   51.64  ? 291 VAL B CG1 1 
ATOM   3369 C  CG2 . VAL B 2 121 ? -7.81   9.841   11.552  1   54.99  ? 291 VAL B CG2 1 
ATOM   3370 N  N   . LEU B 2 122 ? -7.993  7.07    15.192  1   54.51  ? 292 LEU B N   1 
ATOM   3371 C  CA  . LEU B 2 122 ? -7.972  5.799   15.896  1   58.69  ? 292 LEU B CA  1 
ATOM   3372 C  C   . LEU B 2 122 ? -9.144  5.703   16.869  1   59.2   ? 292 LEU B C   1 
ATOM   3373 O  O   . LEU B 2 122 ? -9.744  4.635   16.998  1   55.99  ? 292 LEU B O   1 
ATOM   3374 C  CB  . LEU B 2 122 ? -6.633  5.604   16.609  1   59.39  ? 292 LEU B CB  1 
ATOM   3375 C  CG  . LEU B 2 122 ? -5.432  5.296   15.709  1   56.95  ? 292 LEU B CG  1 
ATOM   3376 C  CD1 . LEU B 2 122 ? -4.27   4.851   16.58   1   55.25  ? 292 LEU B CD1 1 
ATOM   3377 C  CD2 . LEU B 2 122 ? -5.777  4.271   14.621  1   54.48  ? 292 LEU B CD2 1 
ATOM   3378 N  N   . ARG B 2 123 ? -9.478  6.818   17.509  1   60.03  ? 293 ARG B N   1 
ATOM   3379 C  CA  . ARG B 2 123 ? -10.585 6.826   18.495  1   59.61  ? 293 ARG B CA  1 
ATOM   3380 C  C   . ARG B 2 123 ? -11.913 6.649   17.754  1   55.43  ? 293 ARG B C   1 
ATOM   3381 O  O   . ARG B 2 123 ? -12.812 5.999   18.302  1   55.84  ? 293 ARG B O   1 
ATOM   3382 C  CB  . ARG B 2 123 ? -10.518 8.123   19.308  1   58.57  ? 293 ARG B CB  1 
ATOM   3383 C  CG  . ARG B 2 123 ? -9.514  8.087   20.451  1   67.52  ? 293 ARG B CG  1 
ATOM   3384 C  CD  . ARG B 2 123 ? -9.984  8.85    21.679  1   84.2   ? 293 ARG B CD  1 
ATOM   3385 N  NE  . ARG B 2 123 ? -11.169 8.248   22.298  1   97.06  ? 293 ARG B NE  1 
ATOM   3386 C  CZ  . ARG B 2 123 ? -11.183 7.623   23.468  1   105.39 ? 293 ARG B CZ  1 
ATOM   3387 N  NH1 . ARG B 2 123 ? -10.062 7.454   24.144  1   102.81 ? 293 ARG B NH1 1 
ATOM   3388 N  NH2 . ARG B 2 123 ? -12.319 7.165   23.957  1   102.93 ? 293 ARG B NH2 1 
ATOM   3389 N  N   . MET B 2 124 ? -12.018 7.212   16.555  1   49.94  ? 294 MET B N   1 
ATOM   3390 C  CA  . MET B 2 124 ? -13.23  7.058   15.763  1   48.86  ? 294 MET B CA  1 
ATOM   3391 C  C   . MET B 2 124 ? -13.36  5.614   15.276  1   48.25  ? 294 MET B C   1 
ATOM   3392 O  O   . MET B 2 124 ? -14.486 5.108   15.179  1   47.65  ? 294 MET B O   1 
ATOM   3393 C  CB  . MET B 2 124 ? -13.231 7.97    14.536  1   46.58  ? 294 MET B CB  1 
ATOM   3394 C  CG  . MET B 2 124 ? -14.465 7.815   13.652  1   45.84  ? 294 MET B CG  1 
ATOM   3395 S  SD  . MET B 2 124 ? -15.993 8.319   14.471  1   53.05  ? 294 MET B SD  1 
ATOM   3396 C  CE  . MET B 2 124 ? -15.843 10.092  14.751  1   43.05  ? 294 MET B CE  1 
ATOM   3397 N  N   . GLU B 2 125 ? -12.21  5.005   14.926  1   44.62  ? 295 GLU B N   1 
ATOM   3398 C  CA  . GLU B 2 125 ? -12.112 3.603   14.553  1   47.82  ? 295 GLU B CA  1 
ATOM   3399 C  C   . GLU B 2 125 ? -12.81  2.731   15.604  1   50.52  ? 295 GLU B C   1 
ATOM   3400 O  O   . GLU B 2 125 ? -13.694 1.934   15.256  1   51.57  ? 295 GLU B O   1 
ATOM   3401 C  CB  . GLU B 2 125 ? -10.661 3.163   14.351  1   46.98  ? 295 GLU B CB  1 
ATOM   3402 C  CG  . GLU B 2 125 ? -10.579 1.664   14.069  1   46.71  ? 295 GLU B CG  1 
ATOM   3403 C  CD  . GLU B 2 125 ? -9.218  1.067   13.775  1   51.48  ? 295 GLU B CD  1 
ATOM   3404 O  OE1 . GLU B 2 125 ? -8.452  0.802   14.732  1   54.11  ? 295 GLU B OE1 1 
ATOM   3405 O  OE2 . GLU B 2 125 ? -8.933  0.875   12.566  1   52.17  ? 295 GLU B OE2 1 
ATOM   3406 N  N   . HIS B 2 126 ? -12.425 2.94    16.878  1   50.07  ? 296 HIS B N   1 
ATOM   3407 C  CA  . HIS B 2 126 ? -13.001 2.288   18.045  1   57.07  ? 296 HIS B CA  1 
ATOM   3408 C  C   . HIS B 2 126 ? -14.496 2.568   18.194  1   56     ? 296 HIS B C   1 
ATOM   3409 O  O   . HIS B 2 126 ? -15.251 1.65    18.518  1   56.19  ? 296 HIS B O   1 
ATOM   3410 C  CB  . HIS B 2 126 ? -12.335 2.753   19.341  1   66.26  ? 296 HIS B CB  1 
ATOM   3411 C  CG  . HIS B 2 126 ? -11.229 1.919   19.864  1   92.13  ? 296 HIS B CG  1 
ATOM   3412 N  ND1 . HIS B 2 126 ? -11.496 0.69    20.421  1   94.98  ? 296 HIS B ND1 1 
ATOM   3413 C  CD2 . HIS B 2 126 ? -9.912  2.152   20.059  1   115.63 ? 296 HIS B CD2 1 
ATOM   3414 C  CE1 . HIS B 2 126 ? -10.356 0.163   20.849  1   116.61 ? 296 HIS B CE1 1 
ATOM   3415 N  NE2 . HIS B 2 126 ? -9.379  1.029   20.625  1   123.67 ? 296 HIS B NE2 1 
ATOM   3416 N  N   . LEU B 2 127 ? -14.907 3.826   17.965  1   52.31  ? 297 LEU B N   1 
ATOM   3417 C  CA  . LEU B 2 127 ? -16.307 4.188   18.086  1   49.74  ? 297 LEU B CA  1 
ATOM   3418 C  C   . LEU B 2 127 ? -17.14  3.425   17.057  1   49.77  ? 297 LEU B C   1 
ATOM   3419 O  O   . LEU B 2 127 ? -18.204 2.9     17.384  1   48.41  ? 297 LEU B O   1 
ATOM   3420 C  CB  . LEU B 2 127 ? -16.53  5.695   17.996  1   47.22  ? 297 LEU B CB  1 
ATOM   3421 C  CG  . LEU B 2 127 ? -17.948 6.162   18.371  1   44.33  ? 297 LEU B CG  1 
ATOM   3422 C  CD1 . LEU B 2 127 ? -18.4   5.595   19.745  1   36.34  ? 297 LEU B CD1 1 
ATOM   3423 C  CD2 . LEU B 2 127 ? -18.083 7.709   18.347  1   44.13  ? 297 LEU B CD2 1 
ATOM   3424 N  N   . VAL B 2 128 ? -16.661 3.382   15.813  1   49.17  ? 298 VAL B N   1 
ATOM   3425 C  CA  . VAL B 2 128 ? -17.404 2.714   14.757  1   48.24  ? 298 VAL B CA  1 
ATOM   3426 C  C   . VAL B 2 128 ? -17.521 1.23    15.09   1   49.32  ? 298 VAL B C   1 
ATOM   3427 O  O   . VAL B 2 128 ? -18.606 0.645   15.005  1   58.41  ? 298 VAL B O   1 
ATOM   3428 C  CB  . VAL B 2 128 ? -16.817 2.993   13.362  1   44.27  ? 298 VAL B CB  1 
ATOM   3429 C  CG1 . VAL B 2 128 ? -17.489 2.166   12.294  1   41.56  ? 298 VAL B CG1 1 
ATOM   3430 C  CG2 . VAL B 2 128 ? -16.942 4.466   12.999  1   44.71  ? 298 VAL B CG2 1 
ATOM   3431 N  N   . LEU B 2 129 ? -16.413 0.639   15.536  1   48.64  ? 299 LEU B N   1 
ATOM   3432 C  CA  . LEU B 2 129 ? -16.43  -0.764  15.922  1   45.34  ? 299 LEU B CA  1 
ATOM   3433 C  C   . LEU B 2 129 ? -17.491 -1.02   16.992  1   46.03  ? 299 LEU B C   1 
ATOM   3434 O  O   . LEU B 2 129 ? -18.241 -1.991  16.868  1   49.63  ? 299 LEU B O   1 
ATOM   3435 C  CB  . LEU B 2 129 ? -15.039 -1.24   16.324  1   46.03  ? 299 LEU B CB  1 
ATOM   3436 C  CG  . LEU B 2 129 ? -14.012 -1.375  15.194  1   47.76  ? 299 LEU B CG  1 
ATOM   3437 C  CD1 . LEU B 2 129 ? -12.636 -1.633  15.786  1   43.68  ? 299 LEU B CD1 1 
ATOM   3438 C  CD2 . LEU B 2 129 ? -14.426 -2.506  14.268  1   45.55  ? 299 LEU B CD2 1 
ATOM   3439 N  N   . LYS B 2 130 ? -17.576 -0.129  17.996  1   47.19  ? 300 LYS B N   1 
ATOM   3440 C  CA  . LYS B 2 130 ? -18.563 -0.223  19.074  1   50.86  ? 300 LYS B CA  1 
ATOM   3441 C  C   . LYS B 2 130 ? -19.978 -0.136  18.485  1   53.4   ? 300 LYS B C   1 
ATOM   3442 O  O   . LYS B 2 130 ? -20.803 -1.028  18.694  1   55.58  ? 300 LYS B O   1 
ATOM   3443 C  CB  . LYS B 2 130 ? -18.305 0.754   20.237  1   52.77  ? 300 LYS B CB  1 
ATOM   3444 C  CG  . LYS B 2 130 ? -19.463 0.957   21.255  1   68.05  ? 300 LYS B CG  1 
ATOM   3445 C  CD  . LYS B 2 130 ? -19.338 2.041   22.339  1   71.86  ? 300 LYS B CD  1 
ATOM   3446 C  CE  . LYS B 2 130 ? -20.62  2.641   22.867  1   66.75  ? 300 LYS B CE  1 
ATOM   3447 N  NZ  . LYS B 2 130 ? -20.486 3.496   24.057  1   66.56  ? 300 LYS B NZ  1 
ATOM   3448 N  N   . VAL B 2 131 ? -20.233 0.903   17.678  1   48.48  ? 301 VAL B N   1 
ATOM   3449 C  CA  . VAL B 2 131 ? -21.568 1.165   17.166  1   47.2   ? 301 VAL B CA  1 
ATOM   3450 C  C   . VAL B 2 131 ? -22.024 -0.006  16.285  1   47.19  ? 301 VAL B C   1 
ATOM   3451 O  O   . VAL B 2 131 ? -23.18  -0.395  16.35   1   50.16  ? 301 VAL B O   1 
ATOM   3452 C  CB  . VAL B 2 131 ? -21.593 2.539   16.451  1   46.97  ? 301 VAL B CB  1 
ATOM   3453 C  CG1 . VAL B 2 131 ? -22.85  2.754   15.607  1   41.2   ? 301 VAL B CG1 1 
ATOM   3454 C  CG2 . VAL B 2 131 ? -21.382 3.691   17.44   1   42.39  ? 301 VAL B CG2 1 
ATOM   3455 N  N   . LEU B 2 132 ? -21.118 -0.602  15.496  1   45.61  ? 302 LEU B N   1 
ATOM   3456 C  CA  . LEU B 2 132 ? -21.482 -1.687  14.596  1   44.51  ? 302 LEU B CA  1 
ATOM   3457 C  C   . LEU B 2 132 ? -21.385 -3.045  15.302  1   47.85  ? 302 LEU B C   1 
ATOM   3458 O  O   . LEU B 2 132 ? -21.709 -4.089  14.717  1   48.76  ? 302 LEU B O   1 
ATOM   3459 C  CB  . LEU B 2 132 ? -20.563 -1.633  13.373  1   40.69  ? 302 LEU B CB  1 
ATOM   3460 C  CG  . LEU B 2 132 ? -20.56  -0.348  12.539  1   43.05  ? 302 LEU B CG  1 
ATOM   3461 C  CD1 . LEU B 2 132 ? -19.74  -0.519  11.256  1   40.74  ? 302 LEU B CD1 1 
ATOM   3462 C  CD2 . LEU B 2 132 ? -21.933 0.227   12.189  1   39.61  ? 302 LEU B CD2 1 
ATOM   3463 N  N   . ALA B 2 133 ? -20.858 -3.04   16.536  1   45.69  ? 303 ALA B N   1 
ATOM   3464 C  CA  . ALA B 2 133 ? -20.654 -4.257  17.317  1   47.08  ? 303 ALA B CA  1 
ATOM   3465 C  C   . ALA B 2 133 ? -19.834 -5.295  16.534  1   48.02  ? 303 ALA B C   1 
ATOM   3466 O  O   . ALA B 2 133 ? -20.119 -6.505  16.581  1   42.86  ? 303 ALA B O   1 
ATOM   3467 C  CB  . ALA B 2 133 ? -21.983 -4.804  17.822  1   39.18  ? 303 ALA B CB  1 
ATOM   3468 N  N   . PHE B 2 134 ? -18.781 -4.788  15.863  1   46.05  ? 304 PHE B N   1 
ATOM   3469 C  CA  . PHE B 2 134 ? -17.857 -5.564  15.038  1   50.03  ? 304 PHE B CA  1 
ATOM   3470 C  C   . PHE B 2 134 ? -18.528 -6.274  13.855  1   48.87  ? 304 PHE B C   1 
ATOM   3471 O  O   . PHE B 2 134 ? -17.908 -7.1    13.189  1   51.47  ? 304 PHE B O   1 
ATOM   3472 C  CB  . PHE B 2 134 ? -16.986 -6.57   15.798  1   47.45  ? 304 PHE B CB  1 
ATOM   3473 C  CG  . PHE B 2 134 ? -15.863 -5.944  16.604  1   51.64  ? 304 PHE B CG  1 
ATOM   3474 C  CD1 . PHE B 2 134 ? -16.124 -5.305  17.822  1   56.15  ? 304 PHE B CD1 1 
ATOM   3475 C  CD2 . PHE B 2 134 ? -14.55  -5.99   16.143  1   50.05  ? 304 PHE B CD2 1 
ATOM   3476 C  CE1 . PHE B 2 134 ? -15.094 -4.745  18.577  1   53.08  ? 304 PHE B CE1 1 
ATOM   3477 C  CE2 . PHE B 2 134 ? -13.531 -5.411  16.889  1   52.02  ? 304 PHE B CE2 1 
ATOM   3478 C  CZ  . PHE B 2 134 ? -13.797 -4.81   18.108  1   52.81  ? 304 PHE B CZ  1 
ATOM   3479 N  N   A ASP B 2 135 ? -19.777 -5.915  13.555  0.5 49.47  ? 305 ASP B N   1 
ATOM   3480 N  N   B ASP B 2 135 ? -19.76  -5.898  13.54   0.5 47.39  ? 305 ASP B N   1 
ATOM   3481 C  CA  A ASP B 2 135 ? -20.505 -6.643  12.529  0.5 52.12  ? 305 ASP B CA  1 
ATOM   3482 C  CA  B ASP B 2 135 ? -20.467 -6.637  12.513  0.5 48.03  ? 305 ASP B CA  1 
ATOM   3483 C  C   A ASP B 2 135 ? -20.126 -6.125  11.136  0.5 48.04  ? 305 ASP B C   1 
ATOM   3484 C  C   B ASP B 2 135 ? -20.094 -6.105  11.134  0.5 45.81  ? 305 ASP B C   1 
ATOM   3485 O  O   A ASP B 2 135 ? -20.893 -5.365  10.549  0.5 51.49  ? 305 ASP B O   1 
ATOM   3486 O  O   B ASP B 2 135 ? -20.831 -5.328  10.549  0.5 49.21  ? 305 ASP B O   1 
ATOM   3487 C  CB  A ASP B 2 135 ? -21.986 -6.694  12.868  0.5 56.45  ? 305 ASP B CB  1 
ATOM   3488 C  CB  B ASP B 2 135 ? -21.935 -6.709  12.871  0.5 47.52  ? 305 ASP B CB  1 
ATOM   3489 C  CG  A ASP B 2 135 ? -22.747 -7.803  12.165  0.5 64.97  ? 305 ASP B CG  1 
ATOM   3490 C  CG  B ASP B 2 135 ? -22.169 -7.604  14.072  0.5 50.64  ? 305 ASP B CG  1 
ATOM   3491 O  OD1 A ASP B 2 135 ? -22.215 -8.932  12.08   0.5 71.04  ? 305 ASP B OD1 1 
ATOM   3492 O  OD1 B ASP B 2 135 ? -21.249 -8.382  14.406  0.5 58.84  ? 305 ASP B OD1 1 
ATOM   3493 O  OD2 A ASP B 2 135 ? -23.87  -7.536  11.725  0.5 76.73  ? 305 ASP B OD2 1 
ATOM   3494 O  OD2 B ASP B 2 135 ? -23.266 -7.543  14.634  0.5 51.86  ? 305 ASP B OD2 1 
ATOM   3495 N  N   . LEU B 2 136 ? -18.952 -6.549  10.618  1   42.68  ? 306 LEU B N   1 
ATOM   3496 C  CA  . LEU B 2 136 ? -18.3   -5.91   9.474   1   42.9   ? 306 LEU B CA  1 
ATOM   3497 C  C   . LEU B 2 136 ? -18.373 -6.701  8.164   1   43.94  ? 306 LEU B C   1 
ATOM   3498 O  O   . LEU B 2 136 ? -18.049 -6.148  7.112   1   41.44  ? 306 LEU B O   1 
ATOM   3499 C  CB  . LEU B 2 136 ? -16.839 -5.647  9.843   1   48.05  ? 306 LEU B CB  1 
ATOM   3500 C  CG  . LEU B 2 136 ? -16.552 -4.697  11.017  1   51.06  ? 306 LEU B CG  1 
ATOM   3501 C  CD1 . LEU B 2 136 ? -15.145 -4.168  10.871  1   50.83  ? 306 LEU B CD1 1 
ATOM   3502 C  CD2 . LEU B 2 136 ? -17.501 -3.516  11.066  1   47.48  ? 306 LEU B CD2 1 
ATOM   3503 N  N   . ALA B 2 137 ? -18.757 -7.993  8.224   1   45.23  ? 307 ALA B N   1 
ATOM   3504 C  CA  . ALA B 2 137 ? -18.866 -8.846  7.042   1   42.79  ? 307 ALA B CA  1 
ATOM   3505 C  C   . ALA B 2 137 ? -20.209 -8.624  6.349   1   42.03  ? 307 ALA B C   1 
ATOM   3506 O  O   . ALA B 2 137 ? -21.032 -9.533  6.258   1   48.29  ? 307 ALA B O   1 
ATOM   3507 C  CB  . ALA B 2 137 ? -18.665 -10.302 7.391   1   39.42  ? 307 ALA B CB  1 
ATOM   3508 N  N   . ALA B 2 138 ? -20.409 -7.394  5.87    1   41.89  ? 308 ALA B N   1 
ATOM   3509 C  CA  . ALA B 2 138 ? -21.664 -6.935  5.302   1   44.03  ? 308 ALA B CA  1 
ATOM   3510 C  C   . ALA B 2 138 ? -21.753 -7.311  3.823   1   44.07  ? 308 ALA B C   1 
ATOM   3511 O  O   . ALA B 2 138 ? -20.796 -7.129  3.092   1   41.4   ? 308 ALA B O   1 
ATOM   3512 C  CB  . ALA B 2 138 ? -21.741 -5.429  5.44    1   38.71  ? 308 ALA B CB  1 
ATOM   3513 N  N   . PRO B 2 139 ? -22.917 -7.804  3.338   1   44.19  ? 309 PRO B N   1 
ATOM   3514 C  CA  . PRO B 2 139 ? -23.134 -8.011  1.907   1   40.69  ? 309 PRO B CA  1 
ATOM   3515 C  C   . PRO B 2 139 ? -23.14  -6.675  1.192   1   44.72  ? 309 PRO B C   1 
ATOM   3516 O  O   . PRO B 2 139 ? -23.751 -5.722  1.689   1   50.79  ? 309 PRO B O   1 
ATOM   3517 C  CB  . PRO B 2 139 ? -24.515 -8.666  1.825   1   42.03  ? 309 PRO B CB  1 
ATOM   3518 C  CG  . PRO B 2 139 ? -24.753 -9.203  3.228   1   50.26  ? 309 PRO B CG  1 
ATOM   3519 C  CD  . PRO B 2 139 ? -24.079 -8.196  4.159   1   43.24  ? 309 PRO B CD  1 
ATOM   3520 N  N   . THR B 2 140 ? -22.438 -6.636  0.049   1   47.39  ? 310 THR B N   1 
ATOM   3521 C  CA  . THR B 2 140 ? -22.351 -5.469  -0.82   1   46.95  ? 310 THR B CA  1 
ATOM   3522 C  C   . THR B 2 140 ? -23.044 -5.738  -2.158  1   47.92  ? 310 THR B C   1 
ATOM   3523 O  O   . THR B 2 140 ? -23.365 -6.874  -2.495  1   51.05  ? 310 THR B O   1 
ATOM   3524 C  CB  . THR B 2 140 ? -20.891 -5.064  -1.041  1   42.83  ? 310 THR B CB  1 
ATOM   3525 O  OG1 . THR B 2 140 ? -20.197 -6.09   -1.758  1   47.57  ? 310 THR B OG1 1 
ATOM   3526 C  CG2 . THR B 2 140 ? -20.172 -4.754  0.258   1   34.78  ? 310 THR B CG2 1 
ATOM   3527 N  N   . ILE B 2 141 ? -23.236 -4.663  -2.93   1   42.53  ? 311 ILE B N   1 
ATOM   3528 C  CA  . ILE B 2 141 ? -23.719 -4.749  -4.294  1   41.35  ? 311 ILE B CA  1 
ATOM   3529 C  C   . ILE B 2 141 ? -22.782 -5.667  -5.064  1   44.88  ? 311 ILE B C   1 
ATOM   3530 O  O   . ILE B 2 141 ? -23.244 -6.461  -5.877  1   52.64  ? 311 ILE B O   1 
ATOM   3531 C  CB  . ILE B 2 141 ? -23.799 -3.345  -4.926  1   41.96  ? 311 ILE B CB  1 
ATOM   3532 C  CG1 . ILE B 2 141 ? -24.961 -2.541  -4.341  1   40.52  ? 311 ILE B CG1 1 
ATOM   3533 C  CG2 . ILE B 2 141 ? -23.863 -3.397  -6.45   1   39.7   ? 311 ILE B CG2 1 
ATOM   3534 C  CD1 . ILE B 2 141 ? -24.945 -1.068  -4.698  1   36.74  ? 311 ILE B CD1 1 
ATOM   3535 N  N   . ASN B 2 142 ? -21.479 -5.556  -4.786  1   42.52  ? 312 ASN B N   1 
ATOM   3536 C  CA  . ASN B 2 142 ? -20.479 -6.237  -5.594  1   48.93  ? 312 ASN B CA  1 
ATOM   3537 C  C   . ASN B 2 142 ? -20.592 -7.745  -5.414  1   50.94  ? 312 ASN B C   1 
ATOM   3538 O  O   . ASN B 2 142 ? -20.393 -8.491  -6.374  1   49.9   ? 312 ASN B O   1 
ATOM   3539 C  CB  . ASN B 2 142 ? -19.059 -5.706  -5.41   1   47.9   ? 312 ASN B CB  1 
ATOM   3540 C  CG  . ASN B 2 142 ? -18.855 -4.453  -6.233  1   55.06  ? 312 ASN B CG  1 
ATOM   3541 O  OD1 . ASN B 2 142 ? -19.797 -3.693  -6.493  1   62.23  ? 312 ASN B OD1 1 
ATOM   3542 N  ND2 . ASN B 2 142 ? -17.636 -4.209  -6.669  1   58.97  ? 312 ASN B ND2 1 
ATOM   3543 N  N   . GLN B 2 143 ? -20.927 -8.165  -4.187  1   48.81  ? 313 GLN B N   1 
ATOM   3544 C  CA  . GLN B 2 143 ? -20.944 -9.578  -3.843  1   48.83  ? 313 GLN B CA  1 
ATOM   3545 C  C   . GLN B 2 143 ? -22.061 -10.296 -4.595  1   46.69  ? 313 GLN B C   1 
ATOM   3546 O  O   . GLN B 2 143 ? -21.933 -11.478 -4.923  1   47.56  ? 313 GLN B O   1 
ATOM   3547 C  CB  . GLN B 2 143 ? -21.046 -9.743  -2.326  1   48.44  ? 313 GLN B CB  1 
ATOM   3548 C  CG  . GLN B 2 143 ? -19.712 -9.616  -1.595  1   43.6   ? 313 GLN B CG  1 
ATOM   3549 C  CD  . GLN B 2 143 ? -19.932 -9.656  -0.103  1   43.21  ? 313 GLN B CD  1 
ATOM   3550 O  OE1 . GLN B 2 143 ? -20.459 -10.63  0.439   1   42.9   ? 313 GLN B OE1 1 
ATOM   3551 N  NE2 . GLN B 2 143 ? -19.61  -8.558  0.561   1   41     ? 313 GLN B NE2 1 
ATOM   3552 N  N   . PHE B 2 144 ? -23.152 -9.563  -4.859  1   43.03  ? 314 PHE B N   1 
ATOM   3553 C  CA  . PHE B 2 144 ? -24.269 -10.082 -5.625  1   42.3   ? 314 PHE B CA  1 
ATOM   3554 C  C   . PHE B 2 144 ? -23.934 -10.033 -7.109  1   42.63  ? 314 PHE B C   1 
ATOM   3555 O  O   . PHE B 2 144 ? -24.075 -11.062 -7.768  1   49.27  ? 314 PHE B O   1 
ATOM   3556 C  CB  . PHE B 2 144 ? -25.553 -9.332  -5.303  1   40.29  ? 314 PHE B CB  1 
ATOM   3557 C  CG  . PHE B 2 144 ? -26.116 -9.717  -3.955  1   38.73  ? 314 PHE B CG  1 
ATOM   3558 C  CD1 . PHE B 2 144 ? -26.74  -10.959 -3.788  1   44.9   ? 314 PHE B CD1 1 
ATOM   3559 C  CD2 . PHE B 2 144 ? -26.003 -8.857  -2.865  1   35.85  ? 314 PHE B CD2 1 
ATOM   3560 C  CE1 . PHE B 2 144 ? -27.247 -11.354 -2.547  1   41.99  ? 314 PHE B CE1 1 
ATOM   3561 C  CE2 . PHE B 2 144 ? -26.523 -9.244  -1.623  1   42.05  ? 314 PHE B CE2 1 
ATOM   3562 C  CZ  . PHE B 2 144 ? -27.156 -10.485 -1.469  1   42.19  ? 314 PHE B CZ  1 
ATOM   3563 N  N   . LEU B 2 145 ? -23.466 -8.869  -7.595  1   38.84  ? 315 LEU B N   1 
ATOM   3564 C  CA  . LEU B 2 145 ? -23.051 -8.662  -8.983  1   41.06  ? 315 LEU B CA  1 
ATOM   3565 C  C   . LEU B 2 145 ? -22.175 -9.799  -9.507  1   43.11  ? 315 LEU B C   1 
ATOM   3566 O  O   . LEU B 2 145 ? -22.442 -10.335 -10.582 1   43.96  ? 315 LEU B O   1 
ATOM   3567 C  CB  . LEU B 2 145 ? -22.342 -7.335  -9.208  1   38.08  ? 315 LEU B CB  1 
ATOM   3568 C  CG  . LEU B 2 145 ? -23.24  -6.112  -9.4    1   41.62  ? 315 LEU B CG  1 
ATOM   3569 C  CD1 . LEU B 2 145 ? -22.372 -4.877  -9.587  1   44.44  ? 315 LEU B CD1 1 
ATOM   3570 C  CD2 . LEU B 2 145 ? -24.163 -6.25   -10.577 1   40.25  ? 315 LEU B CD2 1 
ATOM   3571 N  N   . THR B 2 146 ? -21.122 -10.146 -8.757  1   43.78  ? 316 THR B N   1 
ATOM   3572 C  CA  . THR B 2 146 ? -20.157 -11.138 -9.219  1   44.4   ? 316 THR B CA  1 
ATOM   3573 C  C   . THR B 2 146 ? -20.856 -12.484 -9.412  1   45.64  ? 316 THR B C   1 
ATOM   3574 O  O   . THR B 2 146 ? -20.511 -13.22  -10.336 1   47.59  ? 316 THR B O   1 
ATOM   3575 C  CB  . THR B 2 146 ? -18.938 -11.224 -8.298  1   42.26  ? 316 THR B CB  1 
ATOM   3576 O  OG1 . THR B 2 146 ? -19.371 -11.502 -6.968  1   43.9   ? 316 THR B OG1 1 
ATOM   3577 C  CG2 . THR B 2 146 ? -18.166 -9.919  -8.271  1   39.48  ? 316 THR B CG2 1 
ATOM   3578 N  N   . GLN B 2 147 ? -21.846 -12.795 -8.555  1   42.71  ? 317 GLN B N   1 
ATOM   3579 C  CA  . GLN B 2 147 ? -22.634 -14.016 -8.722  1   43.31  ? 317 GLN B CA  1 
ATOM   3580 C  C   . GLN B 2 147 ? -23.546 -13.931 -9.945  1   46.79  ? 317 GLN B C   1 
ATOM   3581 O  O   . GLN B 2 147 ? -23.656 -14.887 -10.712 1   47.18  ? 317 GLN B O   1 
ATOM   3582 C  CB  . GLN B 2 147 ? -23.469 -14.272 -7.476  1   40.28  ? 317 GLN B CB  1 
ATOM   3583 C  CG  . GLN B 2 147 ? -22.578 -14.674 -6.317  1   42.89  ? 317 GLN B CG  1 
ATOM   3584 C  CD  . GLN B 2 147 ? -23.329 -15.131 -5.101  1   42.45  ? 317 GLN B CD  1 
ATOM   3585 O  OE1 . GLN B 2 147 ? -22.959 -14.755 -3.993  1   52.93  ? 317 GLN B OE1 1 
ATOM   3586 N  NE2 . GLN B 2 147 ? -24.319 -15.99  -5.274  1   43.46  ? 317 GLN B NE2 1 
ATOM   3587 N  N   . TYR B 2 148 ? -24.224 -12.788 -10.103 1   46.11  ? 318 TYR B N   1 
ATOM   3588 C  CA  . TYR B 2 148 ? -25.112 -12.613 -11.241 1   46.96  ? 318 TYR B CA  1 
ATOM   3589 C  C   . TYR B 2 148 ? -24.318 -12.763 -12.54  1   45.54  ? 318 TYR B C   1 
ATOM   3590 O  O   . TYR B 2 148 ? -24.829 -13.268 -13.536 1   47.84  ? 318 TYR B O   1 
ATOM   3591 C  CB  . TYR B 2 148 ? -25.815 -11.252 -11.166 1   45.15  ? 318 TYR B CB  1 
ATOM   3592 C  CG  . TYR B 2 148 ? -26.716 -10.99  -9.968  1   44.31  ? 318 TYR B CG  1 
ATOM   3593 C  CD1 . TYR B 2 148 ? -27.065 -11.994 -9.059  1   43.43  ? 318 TYR B CD1 1 
ATOM   3594 C  CD2 . TYR B 2 148 ? -27.244 -9.717  -9.756  1   44.04  ? 318 TYR B CD2 1 
ATOM   3595 C  CE1 . TYR B 2 148 ? -27.914 -11.74  -7.985  1   40.24  ? 318 TYR B CE1 1 
ATOM   3596 C  CE2 . TYR B 2 148 ? -28.083 -9.45   -8.68   1   41.46  ? 318 TYR B CE2 1 
ATOM   3597 C  CZ  . TYR B 2 148 ? -28.429 -10.465 -7.798  1   41.06  ? 318 TYR B CZ  1 
ATOM   3598 O  OH  . TYR B 2 148 ? -29.238 -10.189 -6.735  1   39.24  ? 318 TYR B OH  1 
ATOM   3599 N  N   . PHE B 2 149 ? -23.062 -12.311 -12.532 1   47.76  ? 319 PHE B N   1 
ATOM   3600 C  CA  . PHE B 2 149 ? -22.223 -12.315 -13.72  1   45.83  ? 319 PHE B CA  1 
ATOM   3601 C  C   . PHE B 2 149 ? -22.043 -13.744 -14.243 1   47.82  ? 319 PHE B C   1 
ATOM   3602 O  O   . PHE B 2 149 ? -21.908 -13.936 -15.444 1   52.07  ? 319 PHE B O   1 
ATOM   3603 C  CB  . PHE B 2 149 ? -20.852 -11.706 -13.418 1   44.08  ? 319 PHE B CB  1 
ATOM   3604 C  CG  . PHE B 2 149 ? -20.786 -10.2   -13.223 1   43.69  ? 319 PHE B CG  1 
ATOM   3605 C  CD1 . PHE B 2 149 ? -21.853 -9.386  -13.576 1   46.02  ? 319 PHE B CD1 1 
ATOM   3606 C  CD2 . PHE B 2 149 ? -19.635 -9.607  -12.708 1   42.32  ? 319 PHE B CD2 1 
ATOM   3607 C  CE1 . PHE B 2 149 ? -21.781 -8.016  -13.392 1   47.23  ? 319 PHE B CE1 1 
ATOM   3608 C  CE2 . PHE B 2 149 ? -19.549 -8.232  -12.552 1   43.68  ? 319 PHE B CE2 1 
ATOM   3609 C  CZ  . PHE B 2 149 ? -20.629 -7.44   -12.89  1   51.82  ? 319 PHE B CZ  1 
ATOM   3610 N  N   . LEU B 2 150 ? -22.034 -14.744 -13.355 1   43.51  ? 320 LEU B N   1 
ATOM   3611 C  CA  . LEU B 2 150 ? -21.874 -16.137 -13.749 1   47.56  ? 320 LEU B CA  1 
ATOM   3612 C  C   . LEU B 2 150 ? -23.017 -16.634 -14.647 1   54.33  ? 320 LEU B C   1 
ATOM   3613 O  O   . LEU B 2 150 ? -22.987 -17.796 -15.085 1   57.25  ? 320 LEU B O   1 
ATOM   3614 C  CB  . LEU B 2 150 ? -21.762 -17.013 -12.499 1   43.63  ? 320 LEU B CB  1 
ATOM   3615 C  CG  . LEU B 2 150 ? -20.538 -16.759 -11.619 1   51.81  ? 320 LEU B CG  1 
ATOM   3616 C  CD1 . LEU B 2 150 ? -20.541 -17.636 -10.392 1   50.46  ? 320 LEU B CD1 1 
ATOM   3617 C  CD2 . LEU B 2 150 ? -19.246 -16.922 -12.417 1   48.34  ? 320 LEU B CD2 1 
ATOM   3618 N  N   . HIS B 2 151 ? -24.027 -15.782 -14.894 1   51.45  ? 321 HIS B N   1 
ATOM   3619 C  CA  . HIS B 2 151 ? -25.208 -16.181 -15.647 1   55.06  ? 321 HIS B CA  1 
ATOM   3620 C  C   . HIS B 2 151 ? -25.212 -15.581 -17.055 1   64.02  ? 321 HIS B C   1 
ATOM   3621 O  O   . HIS B 2 151 ? -26.159 -15.796 -17.82  1   68.83  ? 321 HIS B O   1 
ATOM   3622 C  CB  . HIS B 2 151 ? -26.486 -15.804 -14.894 1   53.49  ? 321 HIS B CB  1 
ATOM   3623 C  CG  . HIS B 2 151 ? -26.749 -16.667 -13.714 1   53.39  ? 321 HIS B CG  1 
ATOM   3624 N  ND1 . HIS B 2 151 ? -27.765 -17.597 -13.709 1   54.07  ? 321 HIS B ND1 1 
ATOM   3625 C  CD2 . HIS B 2 151 ? -26.124 -16.76  -12.521 1   48.5   ? 321 HIS B CD2 1 
ATOM   3626 C  CE1 . HIS B 2 151 ? -27.753 -18.221 -12.537 1   53.1   ? 321 HIS B CE1 1 
ATOM   3627 N  NE2 . HIS B 2 151 ? -26.762 -17.728 -11.809 1   49.85  ? 321 HIS B NE2 1 
ATOM   3628 N  N   . GLN B 2 152 ? -24.17  -14.8   -17.381 1   65.24  ? 322 GLN B N   1 
ATOM   3629 C  CA  . GLN B 2 152 ? -24.012 -14.288 -18.728 1   65.9   ? 322 GLN B CA  1 
ATOM   3630 C  C   . GLN B 2 152 ? -23.592 -15.453 -19.624 1   81.33  ? 322 GLN B C   1 
ATOM   3631 O  O   . GLN B 2 152 ? -22.771 -16.275 -19.214 1   78.39  ? 322 GLN B O   1 
ATOM   3632 C  CB  . GLN B 2 152 ? -22.859 -13.302 -18.811 1   60.65  ? 322 GLN B CB  1 
ATOM   3633 C  CG  . GLN B 2 152 ? -22.882 -12.129 -17.848 1   70.8   ? 322 GLN B CG  1 
ATOM   3634 C  CD  . GLN B 2 152 ? -21.568 -11.374 -17.917 1   78.47  ? 322 GLN B CD  1 
ATOM   3635 O  OE1 . GLN B 2 152 ? -21.404 -10.459 -18.742 1   70.59  ? 322 GLN B OE1 1 
ATOM   3636 N  NE2 . GLN B 2 152 ? -20.591 -11.817 -17.129 1   64.62  ? 322 GLN B NE2 1 
ATOM   3637 N  N   . GLN B 2 153 ? -24.152 -15.509 -20.847 1   92.46  ? 323 GLN B N   1 
ATOM   3638 C  CA  . GLN B 2 153 ? -23.788 -16.488 -21.866 1   104.22 ? 323 GLN B CA  1 
ATOM   3639 C  C   . GLN B 2 153 ? -23.544 -15.771 -23.197 1   105.29 ? 323 GLN B C   1 
ATOM   3640 O  O   . GLN B 2 153 ? -24.508 -15.407 -23.885 1   91.95  ? 323 GLN B O   1 
ATOM   3641 C  CB  . GLN B 2 153 ? -24.868 -17.558 -22.037 1   108.75 ? 323 GLN B CB  1 
ATOM   3642 C  CG  . GLN B 2 153 ? -24.808 -18.666 -20.996 1   120.36 ? 323 GLN B CG  1 
ATOM   3643 C  CD  . GLN B 2 153 ? -26.11  -19.426 -20.862 1   128.99 ? 323 GLN B CD  1 
ATOM   3644 O  OE1 . GLN B 2 153 ? -27.027 -19.29  -21.679 1   134.84 ? 323 GLN B OE1 1 
ATOM   3645 N  NE2 . GLN B 2 153 ? -26.204 -20.229 -19.812 1   123.52 ? 323 GLN B NE2 1 
ATOM   3646 N  N   . PRO B 2 154 ? -22.265 -15.483 -23.583 1   95.59  ? 324 PRO B N   1 
ATOM   3647 C  CA  . PRO B 2 154 ? -21.075 -15.7   -22.731 1   81.2   ? 324 PRO B CA  1 
ATOM   3648 C  C   . PRO B 2 154 ? -20.692 -14.483 -21.874 1   74.25  ? 324 PRO B C   1 
ATOM   3649 O  O   . PRO B 2 154 ? -21.347 -13.44  -21.958 1   70.29  ? 324 PRO B O   1 
ATOM   3650 C  CB  . PRO B 2 154 ? -20.009 -15.939 -23.815 1   77.75  ? 324 PRO B CB  1 
ATOM   3651 C  CG  . PRO B 2 154 ? -20.385 -14.946 -24.894 1   78.71  ? 324 PRO B CG  1 
ATOM   3652 C  CD  . PRO B 2 154 ? -21.911 -14.907 -24.896 1   84.08  ? 324 PRO B CD  1 
ATOM   3653 N  N   . ALA B 2 155 ? -19.617 -14.596 -21.074 1   66.4   ? 325 ALA B N   1 
ATOM   3654 C  CA  . ALA B 2 155 ? -19.136 -13.457 -20.299 1   61.52  ? 325 ALA B CA  1 
ATOM   3655 C  C   . ALA B 2 155 ? -18.797 -12.296 -21.228 1   62.74  ? 325 ALA B C   1 
ATOM   3656 O  O   . ALA B 2 155 ? -18.22  -12.495 -22.297 1   70.54  ? 325 ALA B O   1 
ATOM   3657 C  CB  . ALA B 2 155 ? -17.93  -13.839 -19.5   1   55.09  ? 325 ALA B CB  1 
ATOM   3658 N  N   . ASN B 2 156 ? -19.18  -11.086 -20.813 1   57.37  ? 326 ASN B N   1 
ATOM   3659 C  CA  . ASN B 2 156 ? -18.901 -9.882  -21.572 1   55.07  ? 326 ASN B CA  1 
ATOM   3660 C  C   . ASN B 2 156 ? -18.4   -8.85   -20.577 1   55.5   ? 326 ASN B C   1 
ATOM   3661 O  O   . ASN B 2 156 ? -19.151 -8.415  -19.702 1   64.65  ? 326 ASN B O   1 
ATOM   3662 C  CB  . ASN B 2 156 ? -20.111 -9.407  -22.381 1   54.34  ? 326 ASN B CB  1 
ATOM   3663 C  CG  . ASN B 2 156 ? -19.849 -8.143  -23.179 1   59.9   ? 326 ASN B CG  1 
ATOM   3664 O  OD1 . ASN B 2 156 ? -19.229 -7.193  -22.676 1   58.95  ? 326 ASN B OD1 1 
ATOM   3665 N  ND2 . ASN B 2 156 ? -20.319 -8.087  -24.423 1   63.46  ? 326 ASN B ND2 1 
ATOM   3666 N  N   . CYS B 2 157 ? -17.129 -8.475  -20.73  1   56.55  ? 327 CYS B N   1 
ATOM   3667 C  CA  . CYS B 2 157 ? -16.431 -7.596  -19.795 1   59.88  ? 327 CYS B CA  1 
ATOM   3668 C  C   . CYS B 2 157 ? -17.002 -6.17   -19.808 1   52.52  ? 327 CYS B C   1 
ATOM   3669 O  O   . CYS B 2 157 ? -16.875 -5.459  -18.821 1   51.07  ? 327 CYS B O   1 
ATOM   3670 C  CB  . CYS B 2 157 ? -14.914 -7.626  -20.011 1   65.13  ? 327 CYS B CB  1 
ATOM   3671 S  SG  . CYS B 2 157 ? -14.418 -6.878  -21.586 1   92.36  ? 327 CYS B SG  1 
ATOM   3672 N  N   . LYS B 2 158 ? -17.584 -5.723  -20.927 1   53.73  ? 328 LYS B N   1 
ATOM   3673 C  CA  . LYS B 2 158 ? -18.245 -4.422  -20.959 1   53.88  ? 328 LYS B CA  1 
ATOM   3674 C  C   . LYS B 2 158 ? -19.487 -4.441  -20.062 1   52.85  ? 328 LYS B C   1 
ATOM   3675 O  O   . LYS B 2 158 ? -19.745 -3.49   -19.335 1   50.78  ? 328 LYS B O   1 
ATOM   3676 C  CB  . LYS B 2 158 ? -18.561 -3.997  -22.397 1   58.48  ? 328 LYS B CB  1 
ATOM   3677 C  CG  . LYS B 2 158 ? -17.443 -3.236  -23.085 1   65.38  ? 328 LYS B CG  1 
ATOM   3678 C  CD  . LYS B 2 158 ? -17.321 -3.545  -24.568 1   78.81  ? 328 LYS B CD  1 
ATOM   3679 C  CE  . LYS B 2 158 ? -18.553 -3.422  -25.411 1   87.97  ? 328 LYS B CE  1 
ATOM   3680 N  NZ  . LYS B 2 158 ? -19.012 -2.042  -25.593 1   93.25  ? 328 LYS B NZ  1 
ATOM   3681 N  N   . VAL B 2 159 ? -20.249 -5.542  -20.119 1   53.91  ? 329 VAL B N   1 
ATOM   3682 C  CA  . VAL B 2 159 ? -21.401 -5.756  -19.262 1   50.7   ? 329 VAL B CA  1 
ATOM   3683 C  C   . VAL B 2 159 ? -20.956 -5.673  -17.803 1   49.04  ? 329 VAL B C   1 
ATOM   3684 O  O   . VAL B 2 159 ? -21.475 -4.854  -17.046 1   50.93  ? 329 VAL B O   1 
ATOM   3685 C  CB  . VAL B 2 159 ? -22.12  -7.079  -19.591 1   50     ? 329 VAL B CB  1 
ATOM   3686 C  CG1 . VAL B 2 159 ? -23.162 -7.475  -18.542 1   49.19  ? 329 VAL B CG1 1 
ATOM   3687 C  CG2 . VAL B 2 159 ? -22.764 -7.019  -20.968 1   50.78  ? 329 VAL B CG2 1 
ATOM   3688 N  N   . GLU B 2 160 ? -19.974 -6.504  -17.435 1   49.91  ? 330 GLU B N   1 
ATOM   3689 C  CA  . GLU B 2 160 ? -19.492 -6.58   -16.063 1   51.11  ? 330 GLU B CA  1 
ATOM   3690 C  C   . GLU B 2 160 ? -19.098 -5.197  -15.555 1   54.43  ? 330 GLU B C   1 
ATOM   3691 O  O   . GLU B 2 160 ? -19.602 -4.79   -14.513 1   61.23  ? 330 GLU B O   1 
ATOM   3692 C  CB  . GLU B 2 160 ? -18.37  -7.599  -15.942 1   51.87  ? 330 GLU B CB  1 
ATOM   3693 C  CG  . GLU B 2 160 ? -18.841 -8.996  -16.332 1   55.83  ? 330 GLU B CG  1 
ATOM   3694 C  CD  . GLU B 2 160 ? -17.82  -10.085 -16.088 1   59.55  ? 330 GLU B CD  1 
ATOM   3695 O  OE1 . GLU B 2 160 ? -16.82  -9.768  -15.426 1   62.94  ? 330 GLU B OE1 1 
ATOM   3696 O  OE2 . GLU B 2 160 ? -18.02  -11.235 -16.537 1   68.61  ? 330 GLU B OE2 1 
ATOM   3697 N  N   . SER B 2 161 ? -18.264 -4.466  -16.316 1   53.26  ? 331 SER B N   1 
ATOM   3698 C  CA  . SER B 2 161 ? -17.761 -3.161  -15.894 1   50.87  ? 331 SER B CA  1 
ATOM   3699 C  C   . SER B 2 161 ? -18.888 -2.133  -15.794 1   51.74  ? 331 SER B C   1 
ATOM   3700 O  O   . SER B 2 161 ? -18.901 -1.321  -14.862 1   49.7   ? 331 SER B O   1 
ATOM   3701 C  CB  . SER B 2 161 ? -16.618 -2.655  -16.753 1   48.19  ? 331 SER B CB  1 
ATOM   3702 O  OG  . SER B 2 161 ? -15.451 -3.436  -16.561 1   52.33  ? 331 SER B OG  1 
ATOM   3703 N  N   . LEU B 2 162 ? -19.817 -2.163  -16.763 1   52.08  ? 332 LEU B N   1 
ATOM   3704 C  CA  . LEU B 2 162 ? -20.912 -1.206  -16.764 1   50.63  ? 332 LEU B CA  1 
ATOM   3705 C  C   . LEU B 2 162 ? -21.791 -1.44   -15.532 1   52.5   ? 332 LEU B C   1 
ATOM   3706 O  O   . LEU B 2 162 ? -22.24  -0.478  -14.91  1   54     ? 332 LEU B O   1 
ATOM   3707 C  CB  . LEU B 2 162 ? -21.728 -1.272  -18.056 1   46.12  ? 332 LEU B CB  1 
ATOM   3708 C  CG  . LEU B 2 162 ? -22.788 -0.178  -18.221 1   47.25  ? 332 LEU B CG  1 
ATOM   3709 C  CD1 . LEU B 2 162 ? -22.193 1.226   -18.04  1   45.63  ? 332 LEU B CD1 1 
ATOM   3710 C  CD2 . LEU B 2 162 ? -23.477 -0.27   -19.562 1   47.39  ? 332 LEU B CD2 1 
ATOM   3711 N  N   . ALA B 2 163 ? -22.051 -2.714  -15.192 1   50.63  ? 333 ALA B N   1 
ATOM   3712 C  CA  . ALA B 2 163 ? -22.838 -3.051  -14.009 1   45.86  ? 333 ALA B CA  1 
ATOM   3713 C  C   . ALA B 2 163 ? -22.172 -2.525  -12.734 1   44.06  ? 333 ALA B C   1 
ATOM   3714 O  O   . ALA B 2 163 ? -22.858 -2.014  -11.864 1   45.31  ? 333 ALA B O   1 
ATOM   3715 C  CB  . ALA B 2 163 ? -23.051 -4.545  -13.928 1   43.2   ? 333 ALA B CB  1 
ATOM   3716 N  N   . MET B 2 164 ? -20.85  -2.694  -12.611 1   42.4   ? 334 MET B N   1 
ATOM   3717 C  CA  . MET B 2 164 ? -20.073 -2.196  -11.477 1   47.75  ? 334 MET B CA  1 
ATOM   3718 C  C   . MET B 2 164 ? -20.216 -0.672  -11.372 1   52.2   ? 334 MET B C   1 
ATOM   3719 O  O   . MET B 2 164 ? -20.355 -0.117  -10.282 1   50.61  ? 334 MET B O   1 
ATOM   3720 C  CB  . MET B 2 164 ? -18.575 -2.516  -11.615 1   47.69  ? 334 MET B CB  1 
ATOM   3721 C  CG  . MET B 2 164 ? -18.147 -3.96   -11.361 1   52.09  ? 334 MET B CG  1 
ATOM   3722 S  SD  . MET B 2 164 ? -18.45  -4.408  -9.639  1   73.14  ? 334 MET B SD  1 
ATOM   3723 C  CE  . MET B 2 164 ? -18.031 -6.158  -9.687  1   79.59  ? 334 MET B CE  1 
ATOM   3724 N  N   . PHE B 2 165 ? -20.18  0.001   -12.529 1   49.45  ? 335 PHE B N   1 
ATOM   3725 C  CA  . PHE B 2 165 ? -20.209 1.448   -12.597 1   47.76  ? 335 PHE B CA  1 
ATOM   3726 C  C   . PHE B 2 165 ? -21.534 1.963   -12.051 1   48.35  ? 335 PHE B C   1 
ATOM   3727 O  O   . PHE B 2 165 ? -21.561 2.84    -11.192 1   51.69  ? 335 PHE B O   1 
ATOM   3728 C  CB  . PHE B 2 165 ? -19.959 1.843   -14.051 1   47.76  ? 335 PHE B CB  1 
ATOM   3729 C  CG  . PHE B 2 165 ? -20.285 3.281   -14.392 1   48.46  ? 335 PHE B CG  1 
ATOM   3730 C  CD1 . PHE B 2 165 ? -19.52  4.323   -13.885 1   49.34  ? 335 PHE B CD1 1 
ATOM   3731 C  CD2 . PHE B 2 165 ? -21.33  3.581   -15.259 1   54.48  ? 335 PHE B CD2 1 
ATOM   3732 C  CE1 . PHE B 2 165 ? -19.81  5.641   -14.224 1   52.77  ? 335 PHE B CE1 1 
ATOM   3733 C  CE2 . PHE B 2 165 ? -21.619 4.902   -15.597 1   54.21  ? 335 PHE B CE2 1 
ATOM   3734 C  CZ  . PHE B 2 165 ? -20.867 5.933   -15.07  1   52.99  ? 335 PHE B CZ  1 
ATOM   3735 N  N   . LEU B 2 166 ? -22.627 1.368   -12.53  1   52.29  ? 336 LEU B N   1 
ATOM   3736 C  CA  . LEU B 2 166 ? -23.986 1.764   -12.19  1   49.49  ? 336 LEU B CA  1 
ATOM   3737 C  C   . LEU B 2 166 ? -24.227 1.549   -10.702 1   50.11  ? 336 LEU B C   1 
ATOM   3738 O  O   . LEU B 2 166 ? -24.749 2.429   -10.025 1   51.71  ? 336 LEU B O   1 
ATOM   3739 C  CB  . LEU B 2 166 ? -24.945 0.935   -13.041 1   47.72  ? 336 LEU B CB  1 
ATOM   3740 C  CG  . LEU B 2 166 ? -24.923 1.239   -14.546 1   42.7   ? 336 LEU B CG  1 
ATOM   3741 C  CD1 . LEU B 2 166 ? -25.825 0.312   -15.331 1   43.47  ? 336 LEU B CD1 1 
ATOM   3742 C  CD2 . LEU B 2 166 ? -25.268 2.68    -14.849 1   38.42  ? 336 LEU B CD2 1 
ATOM   3743 N  N   . GLY B 2 167 ? -23.828 0.373   -10.209 1   47.4   ? 337 GLY B N   1 
ATOM   3744 C  CA  . GLY B 2 167 ? -23.829 0.061   -8.79   1   44.55  ? 337 GLY B CA  1 
ATOM   3745 C  C   . GLY B 2 167 ? -23.067 1.087   -7.955  1   46.7   ? 337 GLY B C   1 
ATOM   3746 O  O   . GLY B 2 167 ? -23.513 1.439   -6.867  1   54.9   ? 337 GLY B O   1 
ATOM   3747 N  N   . GLU B 2 168 ? -21.92  1.561   -8.452  1   45.38  ? 338 GLU B N   1 
ATOM   3748 C  CA  . GLU B 2 168 ? -21.144 2.534   -7.697  1   47.08  ? 338 GLU B CA  1 
ATOM   3749 C  C   . GLU B 2 168 ? -21.849 3.885   -7.671  1   50.82  ? 338 GLU B C   1 
ATOM   3750 O  O   . GLU B 2 168 ? -21.787 4.586   -6.66   1   53.84  ? 338 GLU B O   1 
ATOM   3751 C  CB  . GLU B 2 168 ? -19.743 2.765   -8.247  1   46.42  ? 338 GLU B CB  1 
ATOM   3752 C  CG  . GLU B 2 168 ? -18.718 1.889   -7.556  1   43     ? 338 GLU B CG  1 
ATOM   3753 C  CD  . GLU B 2 168 ? -17.288 2.153   -7.931  1   47.72  ? 338 GLU B CD  1 
ATOM   3754 O  OE1 . GLU B 2 168 ? -16.809 3.303   -7.866  1   50     ? 338 GLU B OE1 1 
ATOM   3755 O  OE2 . GLU B 2 168 ? -16.643 1.148   -8.245  1   49.01  ? 338 GLU B OE2 1 
ATOM   3756 N  N   . LEU B 2 169 ? -22.477 4.254   -8.798  1   47.66  ? 339 LEU B N   1 
ATOM   3757 C  CA  . LEU B 2 169 ? -23.207 5.506   -8.875  1   48.02  ? 339 LEU B CA  1 
ATOM   3758 C  C   . LEU B 2 169 ? -24.274 5.563   -7.776  1   47.07  ? 339 LEU B C   1 
ATOM   3759 O  O   . LEU B 2 169 ? -24.548 6.64    -7.251  1   50.5   ? 339 LEU B O   1 
ATOM   3760 C  CB  . LEU B 2 169 ? -23.803 5.666   -10.272 1   44.45  ? 339 LEU B CB  1 
ATOM   3761 C  CG  . LEU B 2 169 ? -22.856 6.116   -11.385 1   48.44  ? 339 LEU B CG  1 
ATOM   3762 C  CD1 . LEU B 2 169 ? -23.646 6.272   -12.683 1   47.69  ? 339 LEU B CD1 1 
ATOM   3763 C  CD2 . LEU B 2 169 ? -22.14  7.416   -11.056 1   46.9   ? 339 LEU B CD2 1 
ATOM   3764 N  N   . SER B 2 170 ? -24.879 4.411   -7.453  1   42.35  ? 340 SER B N   1 
ATOM   3765 C  CA  . SER B 2 170 ? -25.966 4.303   -6.482  1   47.69  ? 340 SER B CA  1 
ATOM   3766 C  C   . SER B 2 170 ? -25.476 4.617   -5.056  1   48.43  ? 340 SER B C   1 
ATOM   3767 O  O   . SER B 2 170 ? -26.256 5.11    -4.253  1   50.64  ? 340 SER B O   1 
ATOM   3768 C  CB  . SER B 2 170 ? -26.645 2.927   -6.544  1   46.19  ? 340 SER B CB  1 
ATOM   3769 O  OG  . SER B 2 170 ? -25.911 1.964   -5.781  1   42.1   ? 340 SER B OG  1 
ATOM   3770 N  N   . LEU B 2 171 ? -24.197 4.343   -4.742  1   44.06  ? 341 LEU B N   1 
ATOM   3771 C  CA  . LEU B 2 171 ? -23.625 4.695   -3.452  1   45.51  ? 341 LEU B CA  1 
ATOM   3772 C  C   . LEU B 2 171 ? -23.71  6.203   -3.176  1   51.35  ? 341 LEU B C   1 
ATOM   3773 O  O   . LEU B 2 171 ? -23.74  6.615   -2.017  1   50.25  ? 341 LEU B O   1 
ATOM   3774 C  CB  . LEU B 2 171 ? -22.166 4.247   -3.397  1   45.18  ? 341 LEU B CB  1 
ATOM   3775 C  CG  . LEU B 2 171 ? -21.881 2.764   -3.639  1   47.15  ? 341 LEU B CG  1 
ATOM   3776 C  CD1 . LEU B 2 171 ? -20.369 2.571   -3.606  1   44.34  ? 341 LEU B CD1 1 
ATOM   3777 C  CD2 . LEU B 2 171 ? -22.539 1.879   -2.596  1   44.15  ? 341 LEU B CD2 1 
ATOM   3778 N  N   . ILE B 2 172 ? -23.714 7.038   -4.229  1   48.37  ? 342 ILE B N   1 
ATOM   3779 C  CA  . ILE B 2 172 ? -23.579 8.48    -4.053  1   47.71  ? 342 ILE B CA  1 
ATOM   3780 C  C   . ILE B 2 172 ? -24.851 9.083   -3.45   1   54.28  ? 342 ILE B C   1 
ATOM   3781 O  O   . ILE B 2 172 ? -24.774 10.048  -2.687  1   60.33  ? 342 ILE B O   1 
ATOM   3782 C  CB  . ILE B 2 172 ? -23.212 9.183   -5.375  1   47.63  ? 342 ILE B CB  1 
ATOM   3783 C  CG1 . ILE B 2 172 ? -21.887 8.688   -5.973  1   48.36  ? 342 ILE B CG1 1 
ATOM   3784 C  CG2 . ILE B 2 172 ? -23.194 10.697  -5.189  1   47.84  ? 342 ILE B CG2 1 
ATOM   3785 C  CD1 . ILE B 2 172 ? -20.651 9.142   -5.221  1   49.49  ? 342 ILE B CD1 1 
ATOM   3786 N  N   . ASP B 2 173 ? -26.015 8.53    -3.826  1   53.69  ? 343 ASP B N   1 
ATOM   3787 C  CA  . ASP B 2 173 ? -27.314 9.171   -3.67   1   49.78  ? 343 ASP B CA  1 
ATOM   3788 C  C   . ASP B 2 173 ? -28.182 8.379   -2.69   1   53.15  ? 343 ASP B C   1 
ATOM   3789 O  O   . ASP B 2 173 ? -28.917 7.466   -3.079  1   57.54  ? 343 ASP B O   1 
ATOM   3790 C  CB  . ASP B 2 173 ? -27.975 9.374   -5.029  1   48.86  ? 343 ASP B CB  1 
ATOM   3791 C  CG  . ASP B 2 173 ? -27.167 10.24   -5.989  1   55.89  ? 343 ASP B CG  1 
ATOM   3792 O  OD1 . ASP B 2 173 ? -26.692 11.298  -5.542  1   52.94  ? 343 ASP B OD1 1 
ATOM   3793 O  OD2 . ASP B 2 173 ? -26.959 9.833   -7.161  1   57.35  ? 343 ASP B OD2 1 
ATOM   3794 N  N   . ALA B 2 174 ? -28.147 8.76    -1.416  1   53.37  ? 344 ALA B N   1 
ATOM   3795 C  CA  . ALA B 2 174 ? -28.991 8.093   -0.398  1   55.2   ? 344 ALA B CA  1 
ATOM   3796 C  C   . ALA B 2 174 ? -30.438 8.104   -0.866  1   53.26  ? 344 ALA B C   1 
ATOM   3797 O  O   . ALA B 2 174 ? -31.134 7.103   -0.664  1   58.74  ? 344 ALA B O   1 
ATOM   3798 C  CB  . ALA B 2 174 ? -28.842 8.794   0.913   1   57.72  ? 344 ALA B CB  1 
ATOM   3799 N  N   . ASP B 2 175 ? -30.886 9.219   -1.43   1   51.22  ? 345 ASP B N   1 
ATOM   3800 C  CA  . ASP B 2 175 ? -32.235 9.248   -2.045  1   55.14  ? 345 ASP B CA  1 
ATOM   3801 C  C   . ASP B 2 175 ? -32.019 9.112   -3.547  1   58.08  ? 345 ASP B C   1 
ATOM   3802 O  O   . ASP B 2 175 ? -31.465 10.045  -4.142  1   66.61  ? 345 ASP B O   1 
ATOM   3803 C  CB  . ASP B 2 175 ? -33     10.511  -1.693  1   55.19  ? 345 ASP B CB  1 
ATOM   3804 C  CG  . ASP B 2 175 ? -34.409 10.63   -2.251  1   60.17  ? 345 ASP B CG  1 
ATOM   3805 O  OD1 . ASP B 2 175 ? -35.027 9.586   -2.525  1   62.19  ? 345 ASP B OD1 1 
ATOM   3806 O  OD2 . ASP B 2 175 ? -34.881 11.774  -2.393  1   65.88  ? 345 ASP B OD2 1 
ATOM   3807 N  N   . PRO B 2 176 ? -32.404 7.987   -4.174  1   59.36  ? 346 PRO B N   1 
ATOM   3808 C  CA  . PRO B 2 176 ? -33.285 7.031   -3.525  1   53.81  ? 346 PRO B CA  1 
ATOM   3809 C  C   . PRO B 2 176 ? -32.77  5.656   -3.182  1   53.39  ? 346 PRO B C   1 
ATOM   3810 O  O   . PRO B 2 176 ? -33.594 4.809   -2.837  1   59.05  ? 346 PRO B O   1 
ATOM   3811 C  CB  . PRO B 2 176 ? -34.141 6.951   -4.773  1   53.05  ? 346 PRO B CB  1 
ATOM   3812 C  CG  . PRO B 2 176 ? -33.155 6.675   -5.873  1   50.7   ? 346 PRO B CG  1 
ATOM   3813 C  CD  . PRO B 2 176 ? -32.061 7.658   -5.54   1   55.2   ? 346 PRO B CD  1 
ATOM   3814 N  N   . TYR B 2 177 ? -31.46  5.444   -3.186  1   49.07  ? 347 TYR B N   1 
ATOM   3815 C  CA  . TYR B 2 177 ? -30.931 4.059   -3.065  1   51.56  ? 347 TYR B CA  1 
ATOM   3816 C  C   . TYR B 2 177 ? -30.908 3.526   -1.642  1   52.4   ? 347 TYR B C   1 
ATOM   3817 O  O   . TYR B 2 177 ? -30.777 2.305   -1.505  1   56.05  ? 347 TYR B O   1 
ATOM   3818 C  CB  . TYR B 2 177 ? -29.6   4.087   -3.821  1   47.71  ? 347 TYR B CB  1 
ATOM   3819 C  CG  . TYR B 2 177 ? -29.822 4.417   -5.287  1   47.54  ? 347 TYR B CG  1 
ATOM   3820 C  CD1 . TYR B 2 177 ? -30.624 3.609   -6.08   1   45.2   ? 347 TYR B CD1 1 
ATOM   3821 C  CD2 . TYR B 2 177 ? -29.269 5.552   -5.86   1   48.79  ? 347 TYR B CD2 1 
ATOM   3822 C  CE1 . TYR B 2 177 ? -30.852 3.907   -7.411  1   48.21  ? 347 TYR B CE1 1 
ATOM   3823 C  CE2 . TYR B 2 177 ? -29.486 5.86    -7.19   1   50.44  ? 347 TYR B CE2 1 
ATOM   3824 C  CZ  . TYR B 2 177 ? -30.28  5.036   -7.963  1   50.48  ? 347 TYR B CZ  1 
ATOM   3825 O  OH  . TYR B 2 177 ? -30.494 5.343   -9.268  1   52.83  ? 347 TYR B OH  1 
ATOM   3826 N  N   . LEU B 2 178 ? -31.041 4.369   -0.624  1   50.5   ? 348 LEU B N   1 
ATOM   3827 C  CA  . LEU B 2 178 ? -31.072 3.77    0.702   1   51.47  ? 348 LEU B CA  1 
ATOM   3828 C  C   . LEU B 2 178 ? -32.241 2.794   0.855   1   54.16  ? 348 LEU B C   1 
ATOM   3829 O  O   . LEU B 2 178 ? -32.241 1.992   1.791   1   60.1   ? 348 LEU B O   1 
ATOM   3830 C  CB  . LEU B 2 178 ? -31.145 4.823   1.799   1   55.89  ? 348 LEU B CB  1 
ATOM   3831 C  CG  . LEU B 2 178 ? -29.824 5.415   2.289   1   58.23  ? 348 LEU B CG  1 
ATOM   3832 C  CD1 . LEU B 2 178 ? -30.115 6.188   3.578   1   53.96  ? 348 LEU B CD1 1 
ATOM   3833 C  CD2 . LEU B 2 178 ? -28.755 4.354   2.494   1   51.82  ? 348 LEU B CD2 1 
ATOM   3834 N  N   . LYS B 2 179 ? -33.249 2.876   -0.025  1   53.87  ? 349 LYS B N   1 
ATOM   3835 C  CA  . LYS B 2 179 ? -34.482 2.135   0.209   1   61.53  ? 349 LYS B CA  1 
ATOM   3836 C  C   . LYS B 2 179 ? -34.447 0.775   -0.488  1   58.5   ? 349 LYS B C   1 
ATOM   3837 O  O   . LYS B 2 179 ? -35.377 -0.015  -0.35   1   64.11  ? 349 LYS B O   1 
ATOM   3838 C  CB  . LYS B 2 179 ? -35.694 2.978   -0.198  1   70.86  ? 349 LYS B CB  1 
ATOM   3839 C  CG  . LYS B 2 179 ? -35.932 3.075   -1.689  1   78.79  ? 349 LYS B CG  1 
ATOM   3840 C  CD  . LYS B 2 179 ? -37.178 3.88    -2.061  1   80.03  ? 349 LYS B CD  1 
ATOM   3841 C  CE  . LYS B 2 179 ? -37.014 5.358   -1.923  1   82.57  ? 349 LYS B CE  1 
ATOM   3842 N  NZ  . LYS B 2 179 ? -37.854 6.027   -2.927  1   88.73  ? 349 LYS B NZ  1 
ATOM   3843 N  N   . TYR B 2 180 ? -33.367 0.512   -1.226  1   51.91  ? 350 TYR B N   1 
ATOM   3844 C  CA  . TYR B 2 180 ? -33.178 -0.738  -1.934  1   49.22  ? 350 TYR B CA  1 
ATOM   3845 C  C   . TYR B 2 180 ? -32.003 -1.494  -1.317  1   50.7   ? 350 TYR B C   1 
ATOM   3846 O  O   . TYR B 2 180 ? -30.967 -0.898  -0.993  1   49.94  ? 350 TYR B O   1 
ATOM   3847 C  CB  . TYR B 2 180 ? -32.919 -0.485  -3.421  1   47.96  ? 350 TYR B CB  1 
ATOM   3848 C  CG  . TYR B 2 180 ? -33.972 0.326   -4.163  1   51.11  ? 350 TYR B CG  1 
ATOM   3849 C  CD1 . TYR B 2 180 ? -35.255 -0.171  -4.36   1   47.54  ? 350 TYR B CD1 1 
ATOM   3850 C  CD2 . TYR B 2 180 ? -33.659 1.579   -4.698  1   49.16  ? 350 TYR B CD2 1 
ATOM   3851 C  CE1 . TYR B 2 180 ? -36.191 0.557   -5.077  1   51.18  ? 350 TYR B CE1 1 
ATOM   3852 C  CE2 . TYR B 2 180 ? -34.6   2.33    -5.386  1   49.63  ? 350 TYR B CE2 1 
ATOM   3853 C  CZ  . TYR B 2 180 ? -35.873 1.816   -5.574  1   52.54  ? 350 TYR B CZ  1 
ATOM   3854 O  OH  . TYR B 2 180 ? -36.807 2.526   -6.28   1   55.69  ? 350 TYR B OH  1 
ATOM   3855 N  N   . LEU B 2 181 ? -32.202 -2.816  -1.181  1   52.04  ? 351 LEU B N   1 
ATOM   3856 C  CA  . LEU B 2 181 ? -31.187 -3.771  -0.753  1   50.08  ? 351 LEU B CA  1 
ATOM   3857 C  C   . LEU B 2 181 ? -30.097 -3.884  -1.814  1   47.45  ? 351 LEU B C   1 
ATOM   3858 O  O   . LEU B 2 181 ? -30.319 -3.722  -3.016  1   46.21  ? 351 LEU B O   1 
ATOM   3859 C  CB  . LEU B 2 181 ? -31.815 -5.143  -0.474  1   48.79  ? 351 LEU B CB  1 
ATOM   3860 C  CG  . LEU B 2 181 ? -32.805 -5.214  0.7     1   48.06  ? 351 LEU B CG  1 
ATOM   3861 C  CD1 . LEU B 2 181 ? -33.519 -6.544  0.798   1   49.44  ? 351 LEU B CD1 1 
ATOM   3862 C  CD2 . LEU B 2 181 ? -32.148 -4.944  2.047   1   44.93  ? 351 LEU B CD2 1 
ATOM   3863 N  N   . PRO B 2 182 ? -28.864 -4.19   -1.39   1   46.45  ? 352 PRO B N   1 
ATOM   3864 C  CA  . PRO B 2 182 ? -27.771 -4.434  -2.331  1   41.6   ? 352 PRO B CA  1 
ATOM   3865 C  C   . PRO B 2 182 ? -28.123 -5.443  -3.413  1   42.33  ? 352 PRO B C   1 
ATOM   3866 O  O   . PRO B 2 182 ? -27.759 -5.23   -4.557  1   48.5   ? 352 PRO B O   1 
ATOM   3867 C  CB  . PRO B 2 182 ? -26.697 -4.963  -1.415  1   41.47  ? 352 PRO B CB  1 
ATOM   3868 C  CG  . PRO B 2 182 ? -26.954 -4.226  -0.139  1   45.51  ? 352 PRO B CG  1 
ATOM   3869 C  CD  . PRO B 2 182 ? -28.46  -4.255  0.019   1   45.39  ? 352 PRO B CD  1 
ATOM   3870 N  N   . SER B 2 183 ? -28.86  -6.504  -3.066  1   40.86  ? 353 SER B N   1 
ATOM   3871 C  CA  . SER B 2 183 ? -29.175 -7.558  -4.023  1   45.51  ? 353 SER B CA  1 
ATOM   3872 C  C   . SER B 2 183 ? -30.031 -7.017  -5.175  1   50.31  ? 353 SER B C   1 
ATOM   3873 O  O   . SER B 2 183 ? -29.904 -7.501  -6.302  1   50.63  ? 353 SER B O   1 
ATOM   3874 C  CB  . SER B 2 183 ? -29.838 -8.763  -3.344  1   47.1   ? 353 SER B CB  1 
ATOM   3875 O  OG  . SER B 2 183 ? -31.149 -8.469  -2.883  1   47.29  ? 353 SER B OG  1 
ATOM   3876 N  N   . VAL B 2 184 ? -30.894 -6.022  -4.869  1   47.08  ? 354 VAL B N   1 
ATOM   3877 C  CA  . VAL B 2 184 ? -31.865 -5.474  -5.803  1   45.02  ? 354 VAL B CA  1 
ATOM   3878 C  C   . VAL B 2 184 ? -31.223 -4.41   -6.698  1   47.05  ? 354 VAL B C   1 
ATOM   3879 O  O   . VAL B 2 184 ? -31.417 -4.421  -7.917  1   48.17  ? 354 VAL B O   1 
ATOM   3880 C  CB  . VAL B 2 184 ? -33.096 -4.944  -5.043  1   48.1   ? 354 VAL B CB  1 
ATOM   3881 C  CG1 . VAL B 2 184 ? -33.962 -4.006  -5.876  1   41.19  ? 354 VAL B CG1 1 
ATOM   3882 C  CG2 . VAL B 2 184 ? -33.934 -6.079  -4.442  1   42.85  ? 354 VAL B CG2 1 
ATOM   3883 N  N   . ILE B 2 185 ? -30.429 -3.504  -6.114  1   42.98  ? 355 ILE B N   1 
ATOM   3884 C  CA  . ILE B 2 185 ? -29.658 -2.575  -6.927  1   46.95  ? 355 ILE B CA  1 
ATOM   3885 C  C   . ILE B 2 185 ? -28.705 -3.314  -7.876  1   47.98  ? 355 ILE B C   1 
ATOM   3886 O  O   . ILE B 2 185 ? -28.491 -2.878  -9.014  1   45.32  ? 355 ILE B O   1 
ATOM   3887 C  CB  . ILE B 2 185 ? -28.867 -1.599  -6.055  1   46.06  ? 355 ILE B CB  1 
ATOM   3888 C  CG1 . ILE B 2 185 ? -29.779 -0.71   -5.254  1   45.5   ? 355 ILE B CG1 1 
ATOM   3889 C  CG2 . ILE B 2 185 ? -27.919 -0.779  -6.928  1   45.42  ? 355 ILE B CG2 1 
ATOM   3890 C  CD1 . ILE B 2 185 ? -29.046 -0.033  -4.111  1   41.72  ? 355 ILE B CD1 1 
ATOM   3891 N  N   . ALA B 2 186 ? -28.093 -4.393  -7.375  1   44.29  ? 356 ALA B N   1 
ATOM   3892 C  CA  . ALA B 2 186 ? -27.212 -5.222  -8.189  1   44.76  ? 356 ALA B CA  1 
ATOM   3893 C  C   . ALA B 2 186 ? -27.987 -5.809  -9.37   1   43.5   ? 356 ALA B C   1 
ATOM   3894 O  O   . ALA B 2 186 ? -27.482 -5.814  -10.479 1   50.6   ? 356 ALA B O   1 
ATOM   3895 C  CB  . ALA B 2 186 ? -26.526 -6.294  -7.353  1   36.33  ? 356 ALA B CB  1 
ATOM   3896 N  N   . ALA B 2 187 ? -29.22  -6.261  -9.136  1   42.2   ? 357 ALA B N   1 
ATOM   3897 C  CA  . ALA B 2 187 ? -30.036 -6.853  -10.173 1   42.57  ? 357 ALA B CA  1 
ATOM   3898 C  C   . ALA B 2 187 ? -30.373 -5.787  -11.198 1   46     ? 357 ALA B C   1 
ATOM   3899 O  O   . ALA B 2 187 ? -30.175 -6.002  -12.397 1   49.78  ? 357 ALA B O   1 
ATOM   3900 C  CB  . ALA B 2 187 ? -31.295 -7.451  -9.582  1   43.66  ? 357 ALA B CB  1 
ATOM   3901 N  N   . ALA B 2 188 ? -30.858 -4.637  -10.712 1   48.97  ? 358 ALA B N   1 
ATOM   3902 C  CA  . ALA B 2 188 ? -31.204 -3.536  -11.608 1   51.46  ? 358 ALA B CA  1 
ATOM   3903 C  C   . ALA B 2 188 ? -30     -3.152  -12.477 1   49.81  ? 358 ALA B C   1 
ATOM   3904 O  O   . ALA B 2 188 ? -30.111 -3.06   -13.708 1   49.41  ? 358 ALA B O   1 
ATOM   3905 C  CB  . ALA B 2 188 ? -31.742 -2.37   -10.825 1   48.65  ? 358 ALA B CB  1 
ATOM   3906 N  N   . ALA B 2 189 ? -28.834 -3.012  -11.828 1   47.15  ? 359 ALA B N   1 
ATOM   3907 C  CA  . ALA B 2 189 ? -27.597 -2.633  -12.496 1   47.16  ? 359 ALA B CA  1 
ATOM   3908 C  C   . ALA B 2 189 ? -27.175 -3.68   -13.528 1   47.83  ? 359 ALA B C   1 
ATOM   3909 O  O   . ALA B 2 189 ? -26.683 -3.329  -14.596 1   52.75  ? 359 ALA B O   1 
ATOM   3910 C  CB  . ALA B 2 189 ? -26.514 -2.378  -11.474 1   43.63  ? 359 ALA B CB  1 
ATOM   3911 N  N   . PHE B 2 190 ? -27.353 -4.965  -13.214 1   46.07  ? 360 PHE B N   1 
ATOM   3912 C  CA  . PHE B 2 190 ? -26.953 -6.02   -14.134 1   46.52  ? 360 PHE B CA  1 
ATOM   3913 C  C   . PHE B 2 190 ? -27.828 -5.985  -15.385 1   49.01  ? 360 PHE B C   1 
ATOM   3914 O  O   . PHE B 2 190 ? -27.315 -6.077  -16.492 1   58.53  ? 360 PHE B O   1 
ATOM   3915 C  CB  . PHE B 2 190 ? -26.963 -7.399  -13.474 1   44.28  ? 360 PHE B CB  1 
ATOM   3916 C  CG  . PHE B 2 190 ? -26.56  -8.523  -14.414 1   47.37  ? 360 PHE B CG  1 
ATOM   3917 C  CD1 . PHE B 2 190 ? -25.265 -8.604  -14.889 1   46.54  ? 360 PHE B CD1 1 
ATOM   3918 C  CD2 . PHE B 2 190 ? -27.452 -9.518  -14.788 1   52.45  ? 360 PHE B CD2 1 
ATOM   3919 C  CE1 . PHE B 2 190 ? -24.868 -9.639  -15.725 1   49.09  ? 360 PHE B CE1 1 
ATOM   3920 C  CE2 . PHE B 2 190 ? -27.056 -10.545 -15.642 1   57.07  ? 360 PHE B CE2 1 
ATOM   3921 C  CZ  . PHE B 2 190 ? -25.765 -10.604 -16.114 1   50.02  ? 360 PHE B CZ  1 
ATOM   3922 N  N   . HIS B 2 191 ? -29.145 -5.844  -15.213 1   47.86  ? 361 HIS B N   1 
ATOM   3923 C  CA  . HIS B 2 191 ? -30.067 -5.797  -16.337 1   46.16  ? 361 HIS B CA  1 
ATOM   3924 C  C   . HIS B 2 191 ? -29.811 -4.563  -17.197 1   47.38  ? 361 HIS B C   1 
ATOM   3925 O  O   . HIS B 2 191 ? -29.789 -4.634  -18.424 1   48.62  ? 361 HIS B O   1 
ATOM   3926 C  CB  . HIS B 2 191 ? -31.519 -5.788  -15.862 1   44.66  ? 361 HIS B CB  1 
ATOM   3927 C  CG  . HIS B 2 191 ? -32.445 -5.433  -16.967 1   46.04  ? 361 HIS B CG  1 
ATOM   3928 N  ND1 . HIS B 2 191 ? -32.824 -6.369  -17.909 1   49.5   ? 361 HIS B ND1 1 
ATOM   3929 C  CD2 . HIS B 2 191 ? -33.032 -4.269  -17.31  1   46.01  ? 361 HIS B CD2 1 
ATOM   3930 C  CE1 . HIS B 2 191 ? -33.646 -5.799  -18.782 1   52.29  ? 361 HIS B CE1 1 
ATOM   3931 N  NE2 . HIS B 2 191 ? -33.78  -4.522  -18.445 1   53.42  ? 361 HIS B NE2 1 
ATOM   3932 N  N   . LEU B 2 192 ? -29.592 -3.419  -16.553 1   46.22  ? 362 LEU B N   1 
ATOM   3933 C  CA  . LEU B 2 192 ? -29.39  -2.208  -17.323 1   47.77  ? 362 LEU B CA  1 
ATOM   3934 C  C   . LEU B 2 192 ? -28.114 -2.371  -18.147 1   50.88  ? 362 LEU B C   1 
ATOM   3935 O  O   . LEU B 2 192 ? -28.13  -2.162  -19.35  1   49.91  ? 362 LEU B O   1 
ATOM   3936 C  CB  . LEU B 2 192 ? -29.321 -1.065  -16.324 1   48.96  ? 362 LEU B CB  1 
ATOM   3937 C  CG  . LEU B 2 192 ? -29.365 0.343   -16.901 1   53.04  ? 362 LEU B CG  1 
ATOM   3938 C  CD1 . LEU B 2 192 ? -30.448 0.419   -17.948 1   51.84  ? 362 LEU B CD1 1 
ATOM   3939 C  CD2 . LEU B 2 192 ? -29.584 1.327   -15.739 1   52.45  ? 362 LEU B CD2 1 
ATOM   3940 N  N   . ALA B 2 193 ? -27.032 -2.841  -17.513 1   50.64  ? 363 ALA B N   1 
ATOM   3941 C  CA  . ALA B 2 193 ? -25.765 -3.058  -18.189 1   49.95  ? 363 ALA B CA  1 
ATOM   3942 C  C   . ALA B 2 193 ? -25.923 -3.979  -19.395 1   54.96  ? 363 ALA B C   1 
ATOM   3943 O  O   . ALA B 2 193 ? -25.413 -3.678  -20.486 1   60.13  ? 363 ALA B O   1 
ATOM   3944 C  CB  . ALA B 2 193 ? -24.769 -3.618  -17.223 1   45.93  ? 363 ALA B CB  1 
ATOM   3945 N  N   . LEU B 2 194 ? -26.609 -5.104  -19.163 1   50.38  ? 364 LEU B N   1 
ATOM   3946 C  CA  . LEU B 2 194 ? -26.838 -6.144  -20.15  1   52.94  ? 364 LEU B CA  1 
ATOM   3947 C  C   . LEU B 2 194 ? -27.657 -5.592  -21.317 1   58.52  ? 364 LEU B C   1 
ATOM   3948 O  O   . LEU B 2 194 ? -27.325 -5.817  -22.491 1   66.08  ? 364 LEU B O   1 
ATOM   3949 C  CB  . LEU B 2 194 ? -27.582 -7.253  -19.403 1   58.4   ? 364 LEU B CB  1 
ATOM   3950 C  CG  . LEU B 2 194 ? -27.753 -8.594  -20.118 1   64.4   ? 364 LEU B CG  1 
ATOM   3951 C  CD1 . LEU B 2 194 ? -26.404 -9.18   -20.543 1   63.32  ? 364 LEU B CD1 1 
ATOM   3952 C  CD2 . LEU B 2 194 ? -28.451 -9.537  -19.152 1   64.39  ? 364 LEU B CD2 1 
ATOM   3953 N  N   . TYR B 2 195 ? -28.728 -4.861  -20.98  1   53.26  ? 365 TYR B N   1 
ATOM   3954 C  CA  . TYR B 2 195 ? -29.593 -4.252  -21.972 1   52.87  ? 365 TYR B CA  1 
ATOM   3955 C  C   . TYR B 2 195 ? -28.817 -3.215  -22.783 1   53.43  ? 365 TYR B C   1 
ATOM   3956 O  O   . TYR B 2 195 ? -28.857 -3.259  -24.002 1   56.77  ? 365 TYR B O   1 
ATOM   3957 C  CB  . TYR B 2 195 ? -30.858 -3.74   -21.284 1   50.06  ? 365 TYR B CB  1 
ATOM   3958 C  CG  . TYR B 2 195 ? -31.876 -3.167  -22.248 1   54.66  ? 365 TYR B CG  1 
ATOM   3959 C  CD1 . TYR B 2 195 ? -32.569 -3.994  -23.133 1   59.65  ? 365 TYR B CD1 1 
ATOM   3960 C  CD2 . TYR B 2 195 ? -32.126 -1.802  -22.301 1   56.91  ? 365 TYR B CD2 1 
ATOM   3961 C  CE1 . TYR B 2 195 ? -33.483 -3.484  -24.044 1   58.89  ? 365 TYR B CE1 1 
ATOM   3962 C  CE2 . TYR B 2 195 ? -33.048 -1.282  -23.194 1   59.36  ? 365 TYR B CE2 1 
ATOM   3963 C  CZ  . TYR B 2 195 ? -33.732 -2.123  -24.058 1   63.23  ? 365 TYR B CZ  1 
ATOM   3964 O  OH  . TYR B 2 195 ? -34.635 -1.595  -24.939 1   73.86  ? 365 TYR B OH  1 
ATOM   3965 N  N   . THR B 2 196 ? -28.09  -2.318  -22.107 1   51.16  ? 366 THR B N   1 
ATOM   3966 C  CA  . THR B 2 196 ? -27.305 -1.262  -22.746 1   55.04  ? 366 THR B CA  1 
ATOM   3967 C  C   . THR B 2 196 ? -26.302 -1.834  -23.753 1   55.52  ? 366 THR B C   1 
ATOM   3968 O  O   . THR B 2 196 ? -26.22  -1.354  -24.869 1   58.25  ? 366 THR B O   1 
ATOM   3969 C  CB  . THR B 2 196 ? -26.591 -0.388  -21.711 1   54.06  ? 366 THR B CB  1 
ATOM   3970 O  OG1 . THR B 2 196 ? -27.551 0.159   -20.811 1   51.83  ? 366 THR B OG1 1 
ATOM   3971 C  CG2 . THR B 2 196 ? -25.805 0.741   -22.355 1   49.15  ? 366 THR B CG2 1 
ATOM   3972 N  N   . VAL B 2 197 ? -25.561 -2.877  -23.372 1   61.04  ? 367 VAL B N   1 
ATOM   3973 C  CA  . VAL B 2 197 ? -24.42  -3.365  -24.139 1   58.02  ? 367 VAL B CA  1 
ATOM   3974 C  C   . VAL B 2 197 ? -24.882 -4.348  -25.214 1   56.58  ? 367 VAL B C   1 
ATOM   3975 O  O   . VAL B 2 197 ? -24.437 -4.23   -26.357 1   62.32  ? 367 VAL B O   1 
ATOM   3976 C  CB  . VAL B 2 197 ? -23.332 -3.984  -23.234 1   59.62  ? 367 VAL B CB  1 
ATOM   3977 C  CG1 . VAL B 2 197 ? -22.315 -4.808  -24.018 1   58.59  ? 367 VAL B CG1 1 
ATOM   3978 C  CG2 . VAL B 2 197 ? -22.625 -2.941  -22.371 1   53.66  ? 367 VAL B CG2 1 
ATOM   3979 N  N   . THR B 2 198 ? -25.795 -5.279  -24.869 1   55.41  ? 368 THR B N   1 
ATOM   3980 C  CA  . THR B 2 198 ? -26.183 -6.373  -25.773 1   55.06  ? 368 THR B CA  1 
ATOM   3981 C  C   . THR B 2 198 ? -27.672 -6.39   -26.126 1   57.3   ? 368 THR B C   1 
ATOM   3982 O  O   . THR B 2 198 ? -28.104 -7.28   -26.852 1   59.6   ? 368 THR B O   1 
ATOM   3983 C  CB  . THR B 2 198 ? -25.888 -7.751  -25.186 1   51.88  ? 368 THR B CB  1 
ATOM   3984 O  OG1 . THR B 2 198 ? -26.884 -7.98   -24.189 1   52.82  ? 368 THR B OG1 1 
ATOM   3985 C  CG2 . THR B 2 198 ? -24.498 -7.866  -24.592 1   51.63  ? 368 THR B CG2 1 
ATOM   3986 N  N   . GLY B 2 199 ? -28.483 -5.514  -25.533 1   57.09  ? 369 GLY B N   1 
ATOM   3987 C  CA  . GLY B 2 199 ? -29.909 -5.552  -25.806 1   60.13  ? 369 GLY B CA  1 
ATOM   3988 C  C   . GLY B 2 199 ? -30.648 -6.66   -25.055 1   67.13  ? 369 GLY B C   1 
ATOM   3989 O  O   . GLY B 2 199 ? -31.874 -6.74   -25.132 1   74.37  ? 369 GLY B O   1 
ATOM   3990 N  N   . GLN B 2 200 ? -29.927 -7.512  -24.32  1   64.99  ? 370 GLN B N   1 
ATOM   3991 C  CA  . GLN B 2 200 ? -30.589 -8.637  -23.682 1   66.26  ? 370 GLN B CA  1 
ATOM   3992 C  C   . GLN B 2 200 ? -31.184 -8.199  -22.348 1   65.47  ? 370 GLN B C   1 
ATOM   3993 O  O   . GLN B 2 200 ? -30.967 -7.077  -21.905 1   66.86  ? 370 GLN B O   1 
ATOM   3994 C  CB  . GLN B 2 200 ? -29.601 -9.777  -23.495 1   72.02  ? 370 GLN B CB  1 
ATOM   3995 C  CG  . GLN B 2 200 ? -29.127 -10.383 -24.803 1   81.99  ? 370 GLN B CG  1 
ATOM   3996 C  CD  . GLN B 2 200 ? -28.15  -11.494 -24.513 1   89.74  ? 370 GLN B CD  1 
ATOM   3997 O  OE1 . GLN B 2 200 ? -28.506 -12.669 -24.589 1   100.52 ? 370 GLN B OE1 1 
ATOM   3998 N  NE2 . GLN B 2 200 ? -26.949 -11.134 -24.075 1   92.01  ? 370 GLN B NE2 1 
ATOM   3999 N  N   . SER B 2 201 ? -31.935 -9.105  -21.719 1   62.97  ? 371 SER B N   1 
ATOM   4000 C  CA  . SER B 2 201 ? -32.67  -8.783  -20.509 1   61.68  ? 371 SER B CA  1 
ATOM   4001 C  C   . SER B 2 201 ? -32.324 -9.771  -19.402 1   57.41  ? 371 SER B C   1 
ATOM   4002 O  O   . SER B 2 201 ? -31.832 -10.858 -19.68  1   56.08  ? 371 SER B O   1 
ATOM   4003 C  CB  . SER B 2 201 ? -34.152 -8.739  -20.767 1   61.58  ? 371 SER B CB  1 
ATOM   4004 O  OG  . SER B 2 201 ? -34.522 -7.472  -21.291 1   67.71  ? 371 SER B OG  1 
ATOM   4005 N  N   . TRP B 2 202 ? -32.538 -9.335  -18.157 1   58.83  ? 372 TRP B N   1 
ATOM   4006 C  CA  . TRP B 2 202 ? -32.44  -10.134 -16.944 1   58.23  ? 372 TRP B CA  1 
ATOM   4007 C  C   . TRP B 2 202 ? -32.847 -11.577 -17.233 1   57.37  ? 372 TRP B C   1 
ATOM   4008 O  O   . TRP B 2 202 ? -34.006 -11.875 -17.504 1   57.97  ? 372 TRP B O   1 
ATOM   4009 C  CB  . TRP B 2 202 ? -33.326 -9.491  -15.863 1   53.65  ? 372 TRP B CB  1 
ATOM   4010 C  CG  . TRP B 2 202 ? -33.381 -10.172 -14.522 1   54.66  ? 372 TRP B CG  1 
ATOM   4011 C  CD1 . TRP B 2 202 ? -34.451 -10.859 -14.037 1   54.57  ? 372 TRP B CD1 1 
ATOM   4012 C  CD2 . TRP B 2 202 ? -32.378 -10.209 -13.481 1   53.88  ? 372 TRP B CD2 1 
ATOM   4013 N  NE1 . TRP B 2 202 ? -34.192 -11.34  -12.784 1   54.98  ? 372 TRP B NE1 1 
ATOM   4014 C  CE2 . TRP B 2 202 ? -32.934 -10.952 -12.41  1   53.99  ? 372 TRP B CE2 1 
ATOM   4015 C  CE3 . TRP B 2 202 ? -31.076 -9.709  -13.343 1   50.76  ? 372 TRP B CE3 1 
ATOM   4016 C  CZ2 . TRP B 2 202 ? -32.239 -11.194 -11.226 1   48.43  ? 372 TRP B CZ2 1 
ATOM   4017 C  CZ3 . TRP B 2 202 ? -30.388 -9.944  -12.17  1   49.3   ? 372 TRP B CZ3 1 
ATOM   4018 C  CH2 . TRP B 2 202 ? -30.958 -10.686 -11.135 1   49.94  ? 372 TRP B CH2 1 
ATOM   4019 N  N   . PRO B 2 203 ? -31.892 -12.52  -17.168 1   57.06  ? 373 PRO B N   1 
ATOM   4020 C  CA  . PRO B 2 203 ? -32.15  -13.908 -17.565 1   54.9   ? 373 PRO B CA  1 
ATOM   4021 C  C   . PRO B 2 203 ? -33.04  -14.681 -16.592 1   56.58  ? 373 PRO B C   1 
ATOM   4022 O  O   . PRO B 2 203 ? -33.06  -14.417 -15.374 1   52.98  ? 373 PRO B O   1 
ATOM   4023 C  CB  . PRO B 2 203 ? -30.722 -14.485 -17.604 1   56.72  ? 373 PRO B CB  1 
ATOM   4024 C  CG  . PRO B 2 203 ? -29.957 -13.682 -16.567 1   62.57  ? 373 PRO B CG  1 
ATOM   4025 C  CD  . PRO B 2 203 ? -30.509 -12.26  -16.724 1   61.18  ? 373 PRO B CD  1 
ATOM   4026 N  N   . GLU B 2 204 ? -33.739 -15.671 -17.15  1   55.23  ? 374 GLU B N   1 
ATOM   4027 C  CA  . GLU B 2 204 ? -34.615 -16.546 -16.384 1   63.57  ? 374 GLU B CA  1 
ATOM   4028 C  C   . GLU B 2 204 ? -33.854 -17.268 -15.268 1   59.74  ? 374 GLU B C   1 
ATOM   4029 O  O   . GLU B 2 204 ? -34.443 -17.559 -14.222 1   60.22  ? 374 GLU B O   1 
ATOM   4030 C  CB  . GLU B 2 204 ? -35.351 -17.445 -17.38  1   68.94  ? 374 GLU B CB  1 
ATOM   4031 C  CG  . GLU B 2 204 ? -36.374 -18.385 -16.748 1   82.3   ? 374 GLU B CG  1 
ATOM   4032 C  CD  . GLU B 2 204 ? -35.792 -19.636 -16.123 1   87.3   ? 374 GLU B CD  1 
ATOM   4033 O  OE1 . GLU B 2 204 ? -34.69  -20.08  -16.529 1   88.51  ? 374 GLU B OE1 1 
ATOM   4034 O  OE2 . GLU B 2 204 ? -36.455 -20.13  -15.192 1   95.22  ? 374 GLU B OE2 1 
ATOM   4035 N  N   . SER B 2 205 ? -32.584 -17.619 -15.523 1   54.16  ? 375 SER B N   1 
ATOM   4036 C  CA  . SER B 2 205 ? -31.772 -18.346 -14.558 1   56.3   ? 375 SER B CA  1 
ATOM   4037 C  C   . SER B 2 205 ? -31.582 -17.512 -13.282 1   54.78  ? 375 SER B C   1 
ATOM   4038 O  O   . SER B 2 205 ? -31.495 -18.068 -12.185 1   56.6   ? 375 SER B O   1 
ATOM   4039 C  CB  . SER B 2 205 ? -30.463 -18.757 -15.183 1   56.23  ? 375 SER B CB  1 
ATOM   4040 O  OG  . SER B 2 205 ? -29.76  -17.599 -15.617 1   66.77  ? 375 SER B OG  1 
ATOM   4041 N  N   . LEU B 2 206 ? -31.513 -16.178 -13.43  1   53.79  ? 376 LEU B N   1 
ATOM   4042 C  CA  . LEU B 2 206 ? -31.38  -15.268 -12.293 1   50.75  ? 376 LEU B CA  1 
ATOM   4043 C  C   . LEU B 2 206 ? -32.735 -15.064 -11.608 1   47.89  ? 376 LEU B C   1 
ATOM   4044 O  O   . LEU B 2 206 ? -32.772 -14.823 -10.409 1   48.36  ? 376 LEU B O   1 
ATOM   4045 C  CB  . LEU B 2 206 ? -30.706 -13.955 -12.705 1   42.91  ? 376 LEU B CB  1 
ATOM   4046 C  CG  . LEU B 2 206 ? -29.187 -14.056 -12.86  1   45.62  ? 376 LEU B CG  1 
ATOM   4047 C  CD1 . LEU B 2 206 ? -28.591 -12.778 -13.437 1   46.62  ? 376 LEU B CD1 1 
ATOM   4048 C  CD2 . LEU B 2 206 ? -28.542 -14.394 -11.5   1   43.99  ? 376 LEU B CD2 1 
ATOM   4049 N  N   . VAL B 2 207 ? -33.83  -15.188 -12.375 1   46.98  ? 377 VAL B N   1 
ATOM   4050 C  CA  . VAL B 2 207 ? -35.17  -15.221 -11.808 1   54.27  ? 377 VAL B CA  1 
ATOM   4051 C  C   . VAL B 2 207 ? -35.298 -16.429 -10.863 1   53.8   ? 377 VAL B C   1 
ATOM   4052 O  O   . VAL B 2 207 ? -35.853 -16.311 -9.78   1   57.4   ? 377 VAL B O   1 
ATOM   4053 C  CB  . VAL B 2 207 ? -36.251 -15.217 -12.917 1   53.73  ? 377 VAL B CB  1 
ATOM   4054 C  CG1 . VAL B 2 207 ? -37.667 -15.417 -12.375 1   49.56  ? 377 VAL B CG1 1 
ATOM   4055 C  CG2 . VAL B 2 207 ? -36.179 -13.951 -13.759 1   54.24  ? 377 VAL B CG2 1 
ATOM   4056 N  N   . GLN B 2 208 ? -34.8   -17.59  -11.3   1   53.09  ? 378 GLN B N   1 
ATOM   4057 C  CA  . GLN B 2 208 ? -34.731 -18.82  -10.528 1   52.81  ? 378 GLN B CA  1 
ATOM   4058 C  C   . GLN B 2 208 ? -33.873 -18.655 -9.272  1   51.75  ? 378 GLN B C   1 
ATOM   4059 O  O   . GLN B 2 208 ? -34.286 -19.069 -8.19   1   50.63  ? 378 GLN B O   1 
ATOM   4060 C  CB  . GLN B 2 208 ? -34.172 -19.954 -11.393 1   51.95  ? 378 GLN B CB  1 
ATOM   4061 C  CG  . GLN B 2 208 ? -35.083 -20.368 -12.544 1   59.97  ? 378 GLN B CG  1 
ATOM   4062 C  CD  . GLN B 2 208 ? -36.229 -21.251 -12.09  1   63.95  ? 378 GLN B CD  1 
ATOM   4063 O  OE1 . GLN B 2 208 ? -37.319 -21.265 -12.678 1   65.79  ? 378 GLN B OE1 1 
ATOM   4064 N  NE2 . GLN B 2 208 ? -36.01  -21.951 -10.986 1   66.12  ? 378 GLN B NE2 1 
ATOM   4065 N  N   . LYS B 2 209 ? -32.671 -18.081 -9.434  1   50.16  ? 379 LYS B N   1 
ATOM   4066 C  CA  . LYS B 2 209 ? -31.746 -17.896 -8.331  1   50.37  ? 379 LYS B CA  1 
ATOM   4067 C  C   . LYS B 2 209 ? -32.332 -16.952 -7.277  1   50.98  ? 379 LYS B C   1 
ATOM   4068 O  O   . LYS B 2 209 ? -32.345 -17.271 -6.088  1   54.85  ? 379 LYS B O   1 
ATOM   4069 C  CB  . LYS B 2 209 ? -30.428 -17.321 -8.855  1   55.87  ? 379 LYS B CB  1 
ATOM   4070 C  CG  . LYS B 2 209 ? -29.302 -17.261 -7.809  1   57.48  ? 379 LYS B CG  1 
ATOM   4071 C  CD  . LYS B 2 209 ? -28.116 -16.424 -8.28   1   58.39  ? 379 LYS B CD  1 
ATOM   4072 C  CE  . LYS B 2 209 ? -27.004 -16.325 -7.269  1   60.84  ? 379 LYS B CE  1 
ATOM   4073 N  NZ  . LYS B 2 209 ? -26.31  -17.6   -7.058  1   58.19  ? 379 LYS B NZ  1 
ATOM   4074 N  N   . THR B 2 210 ? -32.84  -15.801 -7.727  1   46.56  ? 380 THR B N   1 
ATOM   4075 C  CA  . THR B 2 210 ? -33.084 -14.669 -6.852  1   48.89  ? 380 THR B CA  1 
ATOM   4076 C  C   . THR B 2 210 ? -34.56  -14.553 -6.479  1   50.95  ? 380 THR B C   1 
ATOM   4077 O  O   . THR B 2 210 ? -34.877 -13.889 -5.491  1   58.23  ? 380 THR B O   1 
ATOM   4078 C  CB  . THR B 2 210 ? -32.615 -13.36  -7.499  1   49.81  ? 380 THR B CB  1 
ATOM   4079 O  OG1 . THR B 2 210 ? -33.41  -13.115 -8.656  1   49.09  ? 380 THR B OG1 1 
ATOM   4080 C  CG2 . THR B 2 210 ? -31.145 -13.378 -7.871  1   46.2   ? 380 THR B CG2 1 
ATOM   4081 N  N   . GLY B 2 211 ? -35.45  -15.144 -7.281  1   48.01  ? 381 GLY B N   1 
ATOM   4082 C  CA  . GLY B 2 211 ? -36.876 -14.865 -7.176  1   49.92  ? 381 GLY B CA  1 
ATOM   4083 C  C   . GLY B 2 211 ? -37.265 -13.468 -7.691  1   50.14  ? 381 GLY B C   1 
ATOM   4084 O  O   . GLY B 2 211 ? -38.414 -13.072 -7.559  1   51.74  ? 381 GLY B O   1 
ATOM   4085 N  N   . TYR B 2 212 ? -36.324 -12.705 -8.266  1   47.23  ? 382 TYR B N   1 
ATOM   4086 C  CA  . TYR B 2 212 ? -36.641 -11.364 -8.734  1   49.9   ? 382 TYR B CA  1 
ATOM   4087 C  C   . TYR B 2 212 ? -37.028 -11.418 -10.211 1   53.34  ? 382 TYR B C   1 
ATOM   4088 O  O   . TYR B 2 212 ? -36.468 -12.204 -10.974 1   55.96  ? 382 TYR B O   1 
ATOM   4089 C  CB  . TYR B 2 212 ? -35.453 -10.408 -8.577  1   52.71  ? 382 TYR B CB  1 
ATOM   4090 C  CG  . TYR B 2 212 ? -34.917 -10.127 -7.18   1   50.55  ? 382 TYR B CG  1 
ATOM   4091 C  CD1 . TYR B 2 212 ? -35.721 -10.259 -6.044  1   46.46  ? 382 TYR B CD1 1 
ATOM   4092 C  CD2 . TYR B 2 212 ? -33.598 -9.699  -7.011  1   47.46  ? 382 TYR B CD2 1 
ATOM   4093 C  CE1 . TYR B 2 212 ? -35.211 -9.983  -4.783  1   43.74  ? 382 TYR B CE1 1 
ATOM   4094 C  CE2 . TYR B 2 212 ? -33.081 -9.396  -5.756  1   45.31  ? 382 TYR B CE2 1 
ATOM   4095 C  CZ  . TYR B 2 212 ? -33.89  -9.559  -4.64   1   46.03  ? 382 TYR B CZ  1 
ATOM   4096 O  OH  . TYR B 2 212 ? -33.364 -9.295  -3.408  1   46.42  ? 382 TYR B OH  1 
ATOM   4097 N  N   . THR B 2 213 ? -38.013 -10.598 -10.603 1   59.18  ? 383 THR B N   1 
ATOM   4098 C  CA  . THR B 2 213 ? -38.398 -10.424 -12.003 1   61.88  ? 383 THR B CA  1 
ATOM   4099 C  C   . THR B 2 213 ? -38.248 -8.948  -12.362 1   64.95  ? 383 THR B C   1 
ATOM   4100 O  O   . THR B 2 213 ? -38.042 -8.109  -11.479 1   59.62  ? 383 THR B O   1 
ATOM   4101 C  CB  . THR B 2 213 ? -39.835 -10.878 -12.265 1   57.58  ? 383 THR B CB  1 
ATOM   4102 O  OG1 . THR B 2 213 ? -40.669 -9.934  -11.597 1   59.36  ? 383 THR B OG1 1 
ATOM   4103 C  CG2 . THR B 2 213 ? -40.116 -12.288 -11.779 1   53.47  ? 383 THR B CG2 1 
ATOM   4104 N  N   . LEU B 2 214 ? -38.387 -8.643  -13.658 1   66.22  ? 384 LEU B N   1 
ATOM   4105 C  CA  . LEU B 2 214 ? -38.342 -7.262  -14.103 1   66.54  ? 384 LEU B CA  1 
ATOM   4106 C  C   . LEU B 2 214 ? -39.467 -6.481  -13.444 1   67.04  ? 384 LEU B C   1 
ATOM   4107 O  O   . LEU B 2 214 ? -39.316 -5.286  -13.23  1   72.15  ? 384 LEU B O   1 
ATOM   4108 C  CB  . LEU B 2 214 ? -38.415 -7.169  -15.621 1   69.11  ? 384 LEU B CB  1 
ATOM   4109 C  CG  . LEU B 2 214 ? -37.131 -7.539  -16.362 1   67.18  ? 384 LEU B CG  1 
ATOM   4110 C  CD1 . LEU B 2 214 ? -37.332 -7.461  -17.863 1   68.02  ? 384 LEU B CD1 1 
ATOM   4111 C  CD2 . LEU B 2 214 ? -36.029 -6.611  -15.901 1   66.74  ? 384 LEU B CD2 1 
ATOM   4112 N  N   . GLU B 2 215 ? -40.575 -7.176  -13.142 1   71.02  ? 385 GLU B N   1 
ATOM   4113 C  CA  . GLU B 2 215 ? -41.678 -6.655  -12.345 1   70.61  ? 385 GLU B CA  1 
ATOM   4114 C  C   . GLU B 2 215 ? -41.143 -6.122  -11.015 1   65.74  ? 385 GLU B C   1 
ATOM   4115 O  O   . GLU B 2 215 ? -41.289 -4.942  -10.736 1   65.96  ? 385 GLU B O   1 
ATOM   4116 C  CB  . GLU B 2 215 ? -42.71  -7.759  -12.12  1   79.98  ? 385 GLU B CB  1 
ATOM   4117 C  CG  . GLU B 2 215 ? -43.968 -7.339  -11.364 1   99.08  ? 385 GLU B CG  1 
ATOM   4118 C  CD  . GLU B 2 215 ? -45.089 -6.871  -12.27  1   124.3  ? 385 GLU B CD  1 
ATOM   4119 O  OE1 . GLU B 2 215 ? -44.826 -6.074  -13.199 1   135.57 ? 385 GLU B OE1 1 
ATOM   4120 O  OE2 . GLU B 2 215 ? -46.235 -7.305  -12.034 1   134.04 ? 385 GLU B OE2 1 
ATOM   4121 N  N   . THR B 2 216 ? -40.485 -6.98   -10.225 1   63.22  ? 386 THR B N   1 
ATOM   4122 C  CA  . THR B 2 216 ? -40.043 -6.657  -8.872  1   64.37  ? 386 THR B CA  1 
ATOM   4123 C  C   . THR B 2 216 ? -38.873 -5.66   -8.877  1   62.92  ? 386 THR B C   1 
ATOM   4124 O  O   . THR B 2 216 ? -38.762 -4.865  -7.951  1   59.93  ? 386 THR B O   1 
ATOM   4125 C  CB  . THR B 2 216 ? -39.761 -7.934  -8.064  1   62.53  ? 386 THR B CB  1 
ATOM   4126 O  OG1 . THR B 2 216 ? -38.665 -8.652  -8.621  1   60.23  ? 386 THR B OG1 1 
ATOM   4127 C  CG2 . THR B 2 216 ? -40.945 -8.884  -8.007  1   61.6   ? 386 THR B CG2 1 
ATOM   4128 N  N   . LEU B 2 217 ? -38.031 -5.677  -9.93   1   60.92  ? 387 LEU B N   1 
ATOM   4129 C  CA  . LEU B 2 217 ? -36.905 -4.764  -10.098 1   54.77  ? 387 LEU B CA  1 
ATOM   4130 C  C   . LEU B 2 217 ? -37.304 -3.384  -10.636 1   58.57  ? 387 LEU B C   1 
ATOM   4131 O  O   . LEU B 2 217 ? -36.506 -2.46   -10.545 1   56.26  ? 387 LEU B O   1 
ATOM   4132 C  CB  . LEU B 2 217 ? -35.933 -5.429  -11.068 1   53.84  ? 387 LEU B CB  1 
ATOM   4133 C  CG  . LEU B 2 217 ? -35.29  -6.735  -10.596 1   53.1   ? 387 LEU B CG  1 
ATOM   4134 C  CD1 . LEU B 2 217 ? -34.422 -7.325  -11.687 1   53.63  ? 387 LEU B CD1 1 
ATOM   4135 C  CD2 . LEU B 2 217 ? -34.496 -6.537  -9.314  1   47.09  ? 387 LEU B CD2 1 
ATOM   4136 N  N   . LYS B 2 218 ? -38.513 -3.24   -11.2   1   59.91  ? 388 LYS B N   1 
ATOM   4137 C  CA  . LYS B 2 218 ? -38.932 -2.073  -11.972 1   63.3   ? 388 LYS B CA  1 
ATOM   4138 C  C   . LYS B 2 218 ? -38.697 -0.744  -11.244 1   65.61  ? 388 LYS B C   1 
ATOM   4139 O  O   . LYS B 2 218 ? -38.078 0.166   -11.805 1   70.07  ? 388 LYS B O   1 
ATOM   4140 C  CB  . LYS B 2 218 ? -40.383 -2.199  -12.46  1   65.87  ? 388 LYS B CB  1 
ATOM   4141 C  CG  . LYS B 2 218 ? -40.9   -1.003  -13.268 1   69.99  ? 388 LYS B CG  1 
ATOM   4142 C  CD  . LYS B 2 218 ? -42.292 -1.13   -13.878 1   70.96  ? 388 LYS B CD  1 
ATOM   4143 C  CE  . LYS B 2 218 ? -42.556 -0.008  -14.848 1   80.46  ? 388 LYS B CE  1 
ATOM   4144 N  NZ  . LYS B 2 218 ? -43.647 -0.187  -15.816 1   84.89  ? 388 LYS B NZ  1 
ATOM   4145 N  N   . PRO B 2 219 ? -39.198 -0.537  -10.002 1   63.59  ? 389 PRO B N   1 
ATOM   4146 C  CA  . PRO B 2 219 ? -38.941 0.724   -9.294  1   62.39  ? 389 PRO B CA  1 
ATOM   4147 C  C   . PRO B 2 219 ? -37.466 1.156   -9.308  1   59.74  ? 389 PRO B C   1 
ATOM   4148 O  O   . PRO B 2 219 ? -37.112 2.197   -9.854  1   59.62  ? 389 PRO B O   1 
ATOM   4149 C  CB  . PRO B 2 219 ? -39.485 0.44    -7.888  1   57.98  ? 389 PRO B CB  1 
ATOM   4150 C  CG  . PRO B 2 219 ? -40.557 -0.592  -8.136  1   56.44  ? 389 PRO B CG  1 
ATOM   4151 C  CD  . PRO B 2 219 ? -39.979 -1.491  -9.205  1   59.27  ? 389 PRO B CD  1 
ATOM   4152 N  N   . CYS B 2 220 ? -36.59  0.306   -8.777  1   56.45  ? 390 CYS B N   1 
ATOM   4153 C  CA  . CYS B 2 220 ? -35.151 0.536   -8.721  1   52.71  ? 390 CYS B CA  1 
ATOM   4154 C  C   . CYS B 2 220 ? -34.544 0.847   -10.1   1   52.71  ? 390 CYS B C   1 
ATOM   4155 O  O   . CYS B 2 220 ? -33.773 1.79    -10.257 1   52.17  ? 390 CYS B O   1 
ATOM   4156 C  CB  . CYS B 2 220 ? -34.519 -0.684  -8.065  1   48.2   ? 390 CYS B CB  1 
ATOM   4157 S  SG  . CYS B 2 220 ? -32.754 -0.491  -7.765  1   53.1   ? 390 CYS B SG  1 
ATOM   4158 N  N   . LEU B 2 221 ? -34.885 0.018   -11.091 1   52.32  ? 391 LEU B N   1 
ATOM   4159 C  CA  . LEU B 2 221 ? -34.509 0.154   -12.485 1   55.83  ? 391 LEU B CA  1 
ATOM   4160 C  C   . LEU B 2 221 ? -34.856 1.538   -13.03  1   56.33  ? 391 LEU B C   1 
ATOM   4161 O  O   . LEU B 2 221 ? -34.061 2.144   -13.748 1   60.32  ? 391 LEU B O   1 
ATOM   4162 C  CB  . LEU B 2 221 ? -35.296 -0.957  -13.18  1   64.08  ? 391 LEU B CB  1 
ATOM   4163 C  CG  . LEU B 2 221 ? -34.736 -1.538  -14.479 1   67.53  ? 391 LEU B CG  1 
ATOM   4164 C  CD1 . LEU B 2 221 ? -33.232 -1.386  -14.602 1   62.96  ? 391 LEU B CD1 1 
ATOM   4165 C  CD2 . LEU B 2 221 ? -35.119 -3.015  -14.459 1   70.77  ? 391 LEU B CD2 1 
ATOM   4166 N  N   . LEU B 2 222 ? -36.04  2.053   -12.691 1   56.7   ? 392 LEU B N   1 
ATOM   4167 C  CA  . LEU B 2 222 ? -36.428 3.366   -13.187 1   57.93  ? 392 LEU B CA  1 
ATOM   4168 C  C   . LEU B 2 222 ? -35.534 4.451   -12.591 1   56.72  ? 392 LEU B C   1 
ATOM   4169 O  O   . LEU B 2 222 ? -35.127 5.368   -13.294 1   57.57  ? 392 LEU B O   1 
ATOM   4170 C  CB  . LEU B 2 222 ? -37.903 3.59    -12.894 1   59.59  ? 392 LEU B CB  1 
ATOM   4171 C  CG  . LEU B 2 222 ? -38.839 2.744   -13.758 1   65.02  ? 392 LEU B CG  1 
ATOM   4172 C  CD1 . LEU B 2 222 ? -40.285 3.032   -13.407 1   64.43  ? 392 LEU B CD1 1 
ATOM   4173 C  CD2 . LEU B 2 222 ? -38.579 3.027   -15.231 1   64.84  ? 392 LEU B CD2 1 
ATOM   4174 N  N   . ASP B 2 223 ? -35.197 4.305   -11.304 1   53.88  ? 393 ASP B N   1 
ATOM   4175 C  CA  . ASP B 2 223 ? -34.319 5.241   -10.625 1   53.62  ? 393 ASP B CA  1 
ATOM   4176 C  C   . ASP B 2 223 ? -32.908 5.131   -11.202 1   53.82  ? 393 ASP B C   1 
ATOM   4177 O  O   . ASP B 2 223 ? -32.242 6.141   -11.418 1   55.25  ? 393 ASP B O   1 
ATOM   4178 C  CB  . ASP B 2 223 ? -34.301 5.009   -9.119  1   57.85  ? 393 ASP B CB  1 
ATOM   4179 C  CG  . ASP B 2 223 ? -35.522 5.426   -8.307  1   58.82  ? 393 ASP B CG  1 
ATOM   4180 O  OD1 . ASP B 2 223 ? -36.294 6.291   -8.792  1   60.89  ? 393 ASP B OD1 1 
ATOM   4181 O  OD2 . ASP B 2 223 ? -35.698 4.85    -7.202  1   57.83  ? 393 ASP B OD2 1 
ATOM   4182 N  N   . LEU B 2 224 ? -32.439 3.896   -11.421 1   52.55  ? 394 LEU B N   1 
ATOM   4183 C  CA  . LEU B 2 224 ? -31.073 3.66    -11.872 1   52.15  ? 394 LEU B CA  1 
ATOM   4184 C  C   . LEU B 2 224 ? -30.894 4.207   -13.287 1   53.16  ? 394 LEU B C   1 
ATOM   4185 O  O   . LEU B 2 224 ? -29.865 4.789   -13.609 1   53.16  ? 394 LEU B O   1 
ATOM   4186 C  CB  . LEU B 2 224 ? -30.736 2.169   -11.796 1   52.15  ? 394 LEU B CB  1 
ATOM   4187 C  CG  . LEU B 2 224 ? -29.246 1.836   -11.69  1   50.2   ? 394 LEU B CG  1 
ATOM   4188 C  CD1 . LEU B 2 224 ? -28.638 2.587   -10.519 1   47.13  ? 394 LEU B CD1 1 
ATOM   4189 C  CD2 . LEU B 2 224 ? -29.022 0.354   -11.553 1   44.77  ? 394 LEU B CD2 1 
ATOM   4190 N  N   . HIS B 2 225 ? -31.932 4.035   -14.105 1   53.3   ? 395 HIS B N   1 
ATOM   4191 C  CA  . HIS B 2 225 ? -31.955 4.518   -15.469 1   57.48  ? 395 HIS B CA  1 
ATOM   4192 C  C   . HIS B 2 225 ? -31.87  6.055   -15.495 1   60.77  ? 395 HIS B C   1 
ATOM   4193 O  O   . HIS B 2 225 ? -31.183 6.606   -16.354 1   61.98  ? 395 HIS B O   1 
ATOM   4194 C  CB  . HIS B 2 225 ? -33.173 3.903   -16.169 1   54.85  ? 395 HIS B CB  1 
ATOM   4195 C  CG  . HIS B 2 225 ? -33.348 4.342   -17.578 1   56.25  ? 395 HIS B CG  1 
ATOM   4196 N  ND1 . HIS B 2 225 ? -32.273 4.372   -18.435 1   60.39  ? 395 HIS B ND1 1 
ATOM   4197 C  CD2 . HIS B 2 225 ? -34.408 4.745   -18.288 1   57.97  ? 395 HIS B CD2 1 
ATOM   4198 C  CE1 . HIS B 2 225 ? -32.68  4.781   -19.626 1   61.02  ? 395 HIS B CE1 1 
ATOM   4199 N  NE2 . HIS B 2 225 ? -33.973 5.009   -19.557 1   60.25  ? 395 HIS B NE2 1 
ATOM   4200 N  N   . GLN B 2 226 ? -32.573 6.746   -14.582 1   57.47  ? 396 GLN B N   1 
ATOM   4201 C  CA  . GLN B 2 226 ? -32.474 8.192   -14.452 1   63.85  ? 396 GLN B CA  1 
ATOM   4202 C  C   . GLN B 2 226 ? -31.067 8.592   -13.998 1   63.01  ? 396 GLN B C   1 
ATOM   4203 O  O   . GLN B 2 226 ? -30.476 9.547   -14.532 1   63.8   ? 396 GLN B O   1 
ATOM   4204 C  CB  . GLN B 2 226 ? -33.52  8.79    -13.505 1   75.79  ? 396 GLN B CB  1 
ATOM   4205 C  CG  . GLN B 2 226 ? -34.963 8.678   -13.985 1   89.32  ? 396 GLN B CG  1 
ATOM   4206 C  CD  . GLN B 2 226 ? -35.285 9.625   -15.123 1   105.39 ? 396 GLN B CD  1 
ATOM   4207 O  OE1 . GLN B 2 226 ? -35.464 9.209   -16.277 1   104.13 ? 396 GLN B OE1 1 
ATOM   4208 N  NE2 . GLN B 2 226 ? -35.348 10.914  -14.809 1   104.12 ? 396 GLN B NE2 1 
ATOM   4209 N  N   . THR B 2 227 ? -30.539 7.866   -13.002 1   53.25  ? 397 THR B N   1 
ATOM   4210 C  CA  . THR B 2 227 ? -29.235 8.215   -12.466 1   54.55  ? 397 THR B CA  1 
ATOM   4211 C  C   . THR B 2 227 ? -28.203 8.137   -13.592 1   54.55  ? 397 THR B C   1 
ATOM   4212 O  O   . THR B 2 227 ? -27.348 9.004   -13.719 1   57.8   ? 397 THR B O   1 
ATOM   4213 C  CB  . THR B 2 227 ? -28.895 7.362   -11.24  1   52.42  ? 397 THR B CB  1 
ATOM   4214 O  OG1 . THR B 2 227 ? -29.742 7.802   -10.178 1   51.62  ? 397 THR B OG1 1 
ATOM   4215 C  CG2 . THR B 2 227 ? -27.438 7.464   -10.815 1   47.27  ? 397 THR B CG2 1 
ATOM   4216 N  N   . TYR B 2 228 ? -28.32  7.106   -14.429 1   55.06  ? 398 TYR B N   1 
ATOM   4217 C  CA  . TYR B 2 228 ? -27.426 6.889   -15.556 1   55.09  ? 398 TYR B CA  1 
ATOM   4218 C  C   . TYR B 2 228 ? -27.559 8.008   -16.59  1   60.06  ? 398 TYR B C   1 
ATOM   4219 O  O   . TYR B 2 228 ? -26.548 8.467   -17.102 1   64.24  ? 398 TYR B O   1 
ATOM   4220 C  CB  . TYR B 2 228 ? -27.758 5.513   -16.128 1   50.26  ? 398 TYR B CB  1 
ATOM   4221 C  CG  . TYR B 2 228 ? -26.817 4.956   -17.173 1   51.09  ? 398 TYR B CG  1 
ATOM   4222 C  CD1 . TYR B 2 228 ? -25.555 5.503   -17.401 1   56.13  ? 398 TYR B CD1 1 
ATOM   4223 C  CD2 . TYR B 2 228 ? -27.19  3.833   -17.903 1   52.35  ? 398 TYR B CD2 1 
ATOM   4224 C  CE1 . TYR B 2 228 ? -24.695 4.951   -18.343 1   57.35  ? 398 TYR B CE1 1 
ATOM   4225 C  CE2 . TYR B 2 228 ? -26.347 3.293   -18.861 1   51.82  ? 398 TYR B CE2 1 
ATOM   4226 C  CZ  . TYR B 2 228 ? -25.09  3.838   -19.07  1   54.69  ? 398 TYR B CZ  1 
ATOM   4227 O  OH  . TYR B 2 228 ? -24.287 3.281   -20.026 1   56.99  ? 398 TYR B OH  1 
ATOM   4228 N  N   . LEU B 2 229 ? -28.787 8.45    -16.9   1   60.98  ? 399 LEU B N   1 
ATOM   4229 C  CA  . LEU B 2 229 ? -29.006 9.504   -17.883 1   59.68  ? 399 LEU B CA  1 
ATOM   4230 C  C   . LEU B 2 229 ? -28.395 10.811  -17.397 1   63.46  ? 399 LEU B C   1 
ATOM   4231 O  O   . LEU B 2 229 ? -27.788 11.522  -18.196 1   64.95  ? 399 LEU B O   1 
ATOM   4232 C  CB  . LEU B 2 229 ? -30.476 9.71    -18.243 1   56.74  ? 399 LEU B CB  1 
ATOM   4233 C  CG  . LEU B 2 229 ? -31.111 8.672   -19.18  1   57.85  ? 399 LEU B CG  1 
ATOM   4234 C  CD1 . LEU B 2 229 ? -32.617 8.788   -19.167 1   57.14  ? 399 LEU B CD1 1 
ATOM   4235 C  CD2 . LEU B 2 229 ? -30.641 8.765   -20.618 1   59.79  ? 399 LEU B CD2 1 
ATOM   4236 N  N   . ARG B 2 230 ? -28.579 11.139  -16.122 1   63.36  ? 400 ARG B N   1 
ATOM   4237 C  CA  . ARG B 2 230 ? -28.145 12.467  -15.622 1   68.66  ? 400 ARG B CA  1 
ATOM   4238 C  C   . ARG B 2 230 ? -26.743 12.431  -15.02  1   68.05  ? 400 ARG B C   1 
ATOM   4239 O  O   . ARG B 2 230 ? -26.348 13.432  -14.403 1   68.28  ? 400 ARG B O   1 
ATOM   4240 C  CB  . ARG B 2 230 ? -29.132 12.884  -14.534 1   75.9   ? 400 ARG B CB  1 
ATOM   4241 C  CG  . ARG B 2 230 ? -30.59  12.82   -14.964 1   85.11  ? 400 ARG B CG  1 
ATOM   4242 C  CD  . ARG B 2 230 ? -31.497 13.357  -13.875 1   98.01  ? 400 ARG B CD  1 
ATOM   4243 N  NE  . ARG B 2 230 ? -32.79  12.667  -13.841 1   121.47 ? 400 ARG B NE  1 
ATOM   4244 C  CZ  . ARG B 2 230 ? -33.842 13.088  -13.152 1   120.16 ? 400 ARG B CZ  1 
ATOM   4245 N  NH1 . ARG B 2 230 ? -34.136 12.533  -11.99  1   120.21 ? 400 ARG B NH1 1 
ATOM   4246 N  NH2 . ARG B 2 230 ? -34.6   14.057  -13.632 1   97.39  ? 400 ARG B NH2 1 
ATOM   4247 N  N   . ALA B 2 231 ? -26.015 11.339  -15.211 1   61.28  ? 401 ALA B N   1 
ATOM   4248 C  CA  . ALA B 2 231 ? -24.715 11.217  -14.559 1   61.18  ? 401 ALA B CA  1 
ATOM   4249 C  C   . ALA B 2 231 ? -23.72  12.291  -15.043 1   62.67  ? 401 ALA B C   1 
ATOM   4250 O  O   . ALA B 2 231 ? -22.908 12.802  -14.263 1   61.83  ? 401 ALA B O   1 
ATOM   4251 C  CB  . ALA B 2 231 ? -24.187 9.804   -14.709 1   52.14  ? 401 ALA B CB  1 
ATOM   4252 N  N   . PRO B 2 232 ? -23.686 12.642  -16.35  1   59.33  ? 402 PRO B N   1 
ATOM   4253 C  CA  . PRO B 2 232 ? -22.805 13.719  -16.811 1   60.5   ? 402 PRO B CA  1 
ATOM   4254 C  C   . PRO B 2 232 ? -23.088 15.076  -16.165 1   63.96  ? 402 PRO B C   1 
ATOM   4255 O  O   . PRO B 2 232 ? -22.215 15.928  -16.183 1   68.01  ? 402 PRO B O   1 
ATOM   4256 C  CB  . PRO B 2 232 ? -23.054 13.758  -18.326 1   55.7   ? 402 PRO B CB  1 
ATOM   4257 C  CG  . PRO B 2 232 ? -23.569 12.374  -18.641 1   55.18  ? 402 PRO B CG  1 
ATOM   4258 C  CD  . PRO B 2 232 ? -24.408 11.977  -17.447 1   54.83  ? 402 PRO B CD  1 
ATOM   4259 N  N   . GLN B 2 233 ? -24.286 15.258  -15.585 1   65.13  ? 403 GLN B N   1 
ATOM   4260 C  CA  . GLN B 2 233 ? -24.689 16.502  -14.942 1   65.76  ? 403 GLN B CA  1 
ATOM   4261 C  C   . GLN B 2 233 ? -24.52  16.463  -13.425 1   63.11  ? 403 GLN B C   1 
ATOM   4262 O  O   . GLN B 2 233 ? -24.452 17.53   -12.821 1   62.72  ? 403 GLN B O   1 
ATOM   4263 C  CB  . GLN B 2 233 ? -26.146 16.883  -15.197 1   69.99  ? 403 GLN B CB  1 
ATOM   4264 C  CG  . GLN B 2 233 ? -26.357 17.638  -16.5   1   85.39  ? 403 GLN B CG  1 
ATOM   4265 C  CD  . GLN B 2 233 ? -25.964 16.826  -17.711 1   95.53  ? 403 GLN B CD  1 
ATOM   4266 O  OE1 . GLN B 2 233 ? -25.007 17.151  -18.426 1   100.87 ? 403 GLN B OE1 1 
ATOM   4267 N  NE2 . GLN B 2 233 ? -26.694 15.741  -17.935 1   98.94  ? 403 GLN B NE2 1 
ATOM   4268 N  N   . HIS B 2 234 ? -24.497 15.265  -12.814 1   60.17  ? 404 HIS B N   1 
ATOM   4269 C  CA  . HIS B 2 234 ? -24.366 15.162  -11.361 1   59.74  ? 404 HIS B CA  1 
ATOM   4270 C  C   . HIS B 2 234 ? -23.202 16.04   -10.888 1   59.9   ? 404 HIS B C   1 
ATOM   4271 O  O   . HIS B 2 234 ? -22.195 16.18   -11.582 1   58.74  ? 404 HIS B O   1 
ATOM   4272 C  CB  . HIS B 2 234 ? -24.151 13.708  -10.939 1   57.01  ? 404 HIS B CB  1 
ATOM   4273 C  CG  . HIS B 2 234 ? -24.545 13.391  -9.527  1   59.49  ? 404 HIS B CG  1 
ATOM   4274 N  ND1 . HIS B 2 234 ? -23.801 13.786  -8.435  1   56.54  ? 404 HIS B ND1 1 
ATOM   4275 C  CD2 . HIS B 2 234 ? -25.593 12.678  -9.033  1   53.61  ? 404 HIS B CD2 1 
ATOM   4276 C  CE1 . HIS B 2 234 ? -24.399 13.35   -7.327  1   55.27  ? 404 HIS B CE1 1 
ATOM   4277 N  NE2 . HIS B 2 234 ? -25.489 12.684  -7.667  1   51.93  ? 404 HIS B NE2 1 
ATOM   4278 N  N   . ALA B 2 235 ? -23.358 16.662  -9.718  1   58.18  ? 405 ALA B N   1 
ATOM   4279 C  CA  . ALA B 2 235 ? -22.299 17.461  -9.113  1   58.04  ? 405 ALA B CA  1 
ATOM   4280 C  C   . ALA B 2 235 ? -21.055 16.612  -8.824  1   57.82  ? 405 ALA B C   1 
ATOM   4281 O  O   . ALA B 2 235 ? -19.937 17.126  -8.848  1   55.89  ? 405 ALA B O   1 
ATOM   4282 C  CB  . ALA B 2 235 ? -22.827 18.086  -7.841  1   54.7   ? 405 ALA B CB  1 
ATOM   4283 N  N   . GLN B 2 236 ? -21.272 15.321  -8.507  1   53.23  ? 406 GLN B N   1 
ATOM   4284 C  CA  . GLN B 2 236 ? -20.202 14.397  -8.176  1   52.13  ? 406 GLN B CA  1 
ATOM   4285 C  C   . GLN B 2 236 ? -19.816 13.605  -9.42   1   51.24  ? 406 GLN B C   1 
ATOM   4286 O  O   . GLN B 2 236 ? -20.677 13      -10.032 1   56.97  ? 406 GLN B O   1 
ATOM   4287 C  CB  . GLN B 2 236 ? -20.678 13.451  -7.073  1   52.89  ? 406 GLN B CB  1 
ATOM   4288 C  CG  . GLN B 2 236 ? -20.499 13.967  -5.647  1   54.12  ? 406 GLN B CG  1 
ATOM   4289 C  CD  . GLN B 2 236 ? -21.279 15.228  -5.368  1   62.03  ? 406 GLN B CD  1 
ATOM   4290 O  OE1 . GLN B 2 236 ? -22.478 15.312  -5.652  1   72.25  ? 406 GLN B OE1 1 
ATOM   4291 N  NE2 . GLN B 2 236 ? -20.6   16.23   -4.829  1   64.66  ? 406 GLN B NE2 1 
ATOM   4292 N  N   . GLN B 2 237 ? -18.521 13.567  -9.761  1   51.39  ? 407 GLN B N   1 
ATOM   4293 C  CA  . GLN B 2 237 ? -18.063 13.097  -11.065 1   51.21  ? 407 GLN B CA  1 
ATOM   4294 C  C   . GLN B 2 237 ? -16.946 12.056  -10.966 1   52.47  ? 407 GLN B C   1 
ATOM   4295 O  O   . GLN B 2 237 ? -16.529 11.501  -11.989 1   56.76  ? 407 GLN B O   1 
ATOM   4296 C  CB  . GLN B 2 237 ? -17.592 14.284  -11.912 1   49.85  ? 407 GLN B CB  1 
ATOM   4297 C  CG  . GLN B 2 237 ? -18.734 15.097  -12.512 1   51.73  ? 407 GLN B CG  1 
ATOM   4298 C  CD  . GLN B 2 237 ? -19.548 14.301  -13.508 1   54.49  ? 407 GLN B CD  1 
ATOM   4299 O  OE1 . GLN B 2 237 ? -18.982 13.507  -14.254 1   59.99  ? 407 GLN B OE1 1 
ATOM   4300 N  NE2 . GLN B 2 237 ? -20.866 14.449  -13.516 1   55.08  ? 407 GLN B NE2 1 
ATOM   4301 N  N   . SER B 2 238 ? -16.504 11.748  -9.746  1   48.55  ? 408 SER B N   1 
ATOM   4302 C  CA  . SER B 2 238 ? -15.316 10.935  -9.57   1   51.14  ? 408 SER B CA  1 
ATOM   4303 C  C   . SER B 2 238 ? -15.526 9.508   -10.082 1   52.59  ? 408 SER B C   1 
ATOM   4304 O  O   . SER B 2 238 ? -14.572 8.875   -10.519 1   49.57  ? 408 SER B O   1 
ATOM   4305 C  CB  . SER B 2 238 ? -14.893 10.933  -8.123  1   49.47  ? 408 SER B CB  1 
ATOM   4306 O  OG  . SER B 2 238 ? -14.517 12.243  -7.737  1   50.4   ? 408 SER B OG  1 
ATOM   4307 N  N   . ILE B 2 239 ? -16.753 8.985   -10.011 1   48.26  ? 409 ILE B N   1 
ATOM   4308 C  CA  . ILE B 2 239 ? -16.97  7.624   -10.487 1   49.99  ? 409 ILE B CA  1 
ATOM   4309 C  C   . ILE B 2 239 ? -16.873 7.595   -12.021 1   56.27  ? 409 ILE B C   1 
ATOM   4310 O  O   . ILE B 2 239 ? -16.255 6.702   -12.596 1   57.03  ? 409 ILE B O   1 
ATOM   4311 C  CB  . ILE B 2 239 ? -18.297 7.042   -9.944  1   45.94  ? 409 ILE B CB  1 
ATOM   4312 C  CG1 . ILE B 2 239 ? -18.26  6.783   -8.463  1   41.67  ? 409 ILE B CG1 1 
ATOM   4313 C  CG2 . ILE B 2 239 ? -18.704 5.77    -10.672 1   44.81  ? 409 ILE B CG2 1 
ATOM   4314 C  CD1 . ILE B 2 239 ? -19.633 6.633   -7.848  1   41.61  ? 409 ILE B CD1 1 
ATOM   4315 N  N   . ARG B 2 240 ? -17.47  8.587   -12.693 1   54.15  ? 410 ARG B N   1 
ATOM   4316 C  CA  . ARG B 2 240 ? -17.388 8.675   -14.136 1   55.37  ? 410 ARG B CA  1 
ATOM   4317 C  C   . ARG B 2 240 ? -15.935 8.763   -14.604 1   59.1   ? 410 ARG B C   1 
ATOM   4318 O  O   . ARG B 2 240 ? -15.599 8.14    -15.615 1   59.13  ? 410 ARG B O   1 
ATOM   4319 C  CB  . ARG B 2 240 ? -18.2   9.869   -14.645 1   58.71  ? 410 ARG B CB  1 
ATOM   4320 C  CG  . ARG B 2 240 ? -19.685 9.586   -14.806 1   58.21  ? 410 ARG B CG  1 
ATOM   4321 C  CD  . ARG B 2 240 ? -20.424 10.766  -15.399 1   57.5   ? 410 ARG B CD  1 
ATOM   4322 N  NE  . ARG B 2 240 ? -20.243 10.745  -16.851 1   59.33  ? 410 ARG B NE  1 
ATOM   4323 C  CZ  . ARG B 2 240 ? -19.768 11.709  -17.613 1   55.58  ? 410 ARG B CZ  1 
ATOM   4324 N  NH1 . ARG B 2 240 ? -19.753 11.539  -18.909 1   50.5   ? 410 ARG B NH1 1 
ATOM   4325 N  NH2 . ARG B 2 240 ? -19.336 12.827  -17.084 1   55.38  ? 410 ARG B NH2 1 
ATOM   4326 N  N   . GLU B 2 241 ? -15.098 9.538   -13.895 1   58.91  ? 411 GLU B N   1 
ATOM   4327 C  CA  . GLU B 2 241 ? -13.684 9.681   -14.226 1   61.14  ? 411 GLU B CA  1 
ATOM   4328 C  C   . GLU B 2 241 ? -12.96  8.334   -14.12  1   59.42  ? 411 GLU B C   1 
ATOM   4329 O  O   . GLU B 2 241 ? -12.123 8.024   -14.96  1   62.21  ? 411 GLU B O   1 
ATOM   4330 C  CB  . GLU B 2 241 ? -12.999 10.684  -13.295 1   64.58  ? 411 GLU B CB  1 
ATOM   4331 C  CG  . GLU B 2 241 ? -13.714 12.029  -13.185 1   74.84  ? 411 GLU B CG  1 
ATOM   4332 C  CD  . GLU B 2 241 ? -13.677 12.898  -14.431 1   79.74  ? 411 GLU B CD  1 
ATOM   4333 O  OE1 . GLU B 2 241 ? -12.815 12.673  -15.31  1   82.46  ? 411 GLU B OE1 1 
ATOM   4334 O  OE2 . GLU B 2 241 ? -14.519 13.818  -14.526 1   83.31  ? 411 GLU B OE2 1 
ATOM   4335 N  N   . LYS B 2 242 ? -13.262 7.558   -13.072 1   54.23  ? 412 LYS B N   1 
ATOM   4336 C  CA  . LYS B 2 242 ? -12.62  6.289   -12.775 1   53.99  ? 412 LYS B CA  1 
ATOM   4337 C  C   . LYS B 2 242 ? -12.999 5.259   -13.831 1   54.1   ? 412 LYS B C   1 
ATOM   4338 O  O   . LYS B 2 242 ? -12.149 4.468   -14.222 1   60.71  ? 412 LYS B O   1 
ATOM   4339 C  CB  . LYS B 2 242 ? -13.024 5.851   -11.359 1   49.84  ? 412 LYS B CB  1 
ATOM   4340 C  CG  . LYS B 2 242 ? -12.959 4.375   -11.028 1   49.3   ? 412 LYS B CG  1 
ATOM   4341 C  CD  . LYS B 2 242 ? -13.344 4.129   -9.571  1   47.25  ? 412 LYS B CD  1 
ATOM   4342 C  CE  . LYS B 2 242 ? -13.345 2.681   -9.162  1   43.98  ? 412 LYS B CE  1 
ATOM   4343 N  NZ  . LYS B 2 242 ? -13.959 2.533   -7.836  1   41.29  ? 412 LYS B NZ  1 
ATOM   4344 N  N   . TYR B 2 243 ? -14.251 5.303   -14.302 1   50.73  ? 413 TYR B N   1 
ATOM   4345 C  CA  . TYR B 2 243 ? -14.723 4.334   -15.279 1   52.97  ? 413 TYR B CA  1 
ATOM   4346 C  C   . TYR B 2 243 ? -14.382 4.734   -16.729 1   53.8   ? 413 TYR B C   1 
ATOM   4347 O  O   . TYR B 2 243 ? -14.688 3.959   -17.641 1   57.69  ? 413 TYR B O   1 
ATOM   4348 C  CB  . TYR B 2 243 ? -16.18  3.999   -14.943 1   48.35  ? 413 TYR B CB  1 
ATOM   4349 C  CG  . TYR B 2 243 ? -16.282 2.966   -13.835 1   48.39  ? 413 TYR B CG  1 
ATOM   4350 C  CD1 . TYR B 2 243 ? -16.2   3.364   -12.505 1   48.01  ? 413 TYR B CD1 1 
ATOM   4351 C  CD2 . TYR B 2 243 ? -16.45  1.611   -14.117 1   43.74  ? 413 TYR B CD2 1 
ATOM   4352 C  CE1 . TYR B 2 243 ? -16.29  2.442   -11.475 1   44.59  ? 413 TYR B CE1 1 
ATOM   4353 C  CE2 . TYR B 2 243 ? -16.524 0.676   -13.099 1   45.7   ? 413 TYR B CE2 1 
ATOM   4354 C  CZ  . TYR B 2 243 ? -16.44  1.096   -11.776 1   49.22  ? 413 TYR B CZ  1 
ATOM   4355 O  OH  . TYR B 2 243 ? -16.511 0.197   -10.747 1   45.55  ? 413 TYR B OH  1 
ATOM   4356 N  N   . LYS B 2 244 ? -13.742 5.9     -16.949 1   51.08  ? 414 LYS B N   1 
ATOM   4357 C  CA  . LYS B 2 244 ? -13.165 6.249   -18.245 1   56.84  ? 414 LYS B CA  1 
ATOM   4358 C  C   . LYS B 2 244 ? -11.893 5.428   -18.455 1   61.01  ? 414 LYS B C   1 
ATOM   4359 O  O   . LYS B 2 244 ? -11.473 5.197   -19.593 1   65.78  ? 414 LYS B O   1 
ATOM   4360 C  CB  . LYS B 2 244 ? -12.81  7.736   -18.416 1   56.42  ? 414 LYS B CB  1 
ATOM   4361 C  CG  . LYS B 2 244 ? -13.932 8.746   -18.504 1   59.17  ? 414 LYS B CG  1 
ATOM   4362 C  CD  . LYS B 2 244 ? -13.44  10.183  -18.529 1   60.17  ? 414 LYS B CD  1 
ATOM   4363 C  CE  . LYS B 2 244 ? -14.283 11.101  -17.641 1   70.02  ? 414 LYS B CE  1 
ATOM   4364 N  NZ  . LYS B 2 244 ? -15.743 11.217  -17.852 1   74.52  ? 414 LYS B NZ  1 
ATOM   4365 N  N   . ASN B 2 245 ? -11.305 4.968   -17.338 1   59.42  ? 415 ASN B N   1 
ATOM   4366 C  CA  . ASN B 2 245 ? -10.071 4.196   -17.346 1   62.96  ? 415 ASN B CA  1 
ATOM   4367 C  C   . ASN B 2 245 ? -10.279 2.85    -18.037 1   61.15  ? 415 ASN B C   1 
ATOM   4368 O  O   . ASN B 2 245 ? -11.379 2.291   -17.998 1   57.73  ? 415 ASN B O   1 
ATOM   4369 C  CB  . ASN B 2 245 ? -9.509  4.039   -15.935 1   68.49  ? 415 ASN B CB  1 
ATOM   4370 C  CG  . ASN B 2 245 ? -8.075  3.557   -15.908 1   80.08  ? 415 ASN B CG  1 
ATOM   4371 O  OD1 . ASN B 2 245 ? -7.815  2.363   -16.114 1   80.71  ? 415 ASN B OD1 1 
ATOM   4372 N  ND2 . ASN B 2 245 ? -7.139  4.468   -15.661 1   85.29  ? 415 ASN B ND2 1 
ATOM   4373 N  N   . SER B 2 246 ? -9.18   2.314   -18.595 1   61.21  ? 416 SER B N   1 
ATOM   4374 C  CA  . SER B 2 246 ? -9.182  1.088   -19.379 1   63.18  ? 416 SER B CA  1 
ATOM   4375 C  C   . SER B 2 246 ? -9.374  -0.154  -18.504 1   62.66  ? 416 SER B C   1 
ATOM   4376 O  O   . SER B 2 246 ? -9.946  -1.144  -18.964 1   65.91  ? 416 SER B O   1 
ATOM   4377 C  CB  . SER B 2 246 ? -7.959  0.992   -20.23  1   64.67  ? 416 SER B CB  1 
ATOM   4378 O  OG  . SER B 2 246 ? -6.821  1.288   -19.436 1   85.81  ? 416 SER B OG  1 
ATOM   4379 N  N   . LYS B 2 247 ? -8.926  -0.086  -17.245 1   60.6   ? 417 LYS B N   1 
ATOM   4380 C  CA  . LYS B 2 247 ? -9.158  -1.125  -16.256 1   60.87  ? 417 LYS B CA  1 
ATOM   4381 C  C   . LYS B 2 247 ? -10.629 -1.52   -16.295 1   60.75  ? 417 LYS B C   1 
ATOM   4382 O  O   . LYS B 2 247 ? -10.923 -2.706  -16.196 1   63.67  ? 417 LYS B O   1 
ATOM   4383 C  CB  . LYS B 2 247 ? -8.677  -0.618  -14.892 1   60.72  ? 417 LYS B CB  1 
ATOM   4384 C  CG  . LYS B 2 247 ? -8.903  -1.51   -13.69  1   68.07  ? 417 LYS B CG  1 
ATOM   4385 C  CD  . LYS B 2 247 ? -8.386  -0.863  -12.402 1   74.11  ? 417 LYS B CD  1 
ATOM   4386 C  CE  . LYS B 2 247 ? -8.152  -1.77   -11.228 1   79.82  ? 417 LYS B CE  1 
ATOM   4387 N  NZ  . LYS B 2 247 ? -9.04   -2.937  -11.23  1   92.56  ? 417 LYS B NZ  1 
ATOM   4388 N  N   . TYR B 2 248 ? -11.517 -0.532  -16.517 1   59.39  ? 418 TYR B N   1 
ATOM   4389 C  CA  . TYR B 2 248 ? -12.962 -0.715  -16.485 1   56.63  ? 418 TYR B CA  1 
ATOM   4390 C  C   . TYR B 2 248 ? -13.573 -0.576  -17.878 1   56.35  ? 418 TYR B C   1 
ATOM   4391 O  O   . TYR B 2 248 ? -14.763 -0.267  -17.988 1   59.99  ? 418 TYR B O   1 
ATOM   4392 C  CB  . TYR B 2 248 ? -13.571 0.315   -15.527 1   58.66  ? 418 TYR B CB  1 
ATOM   4393 C  CG  . TYR B 2 248 ? -12.938 0.318   -14.143 1   58.72  ? 418 TYR B CG  1 
ATOM   4394 C  CD1 . TYR B 2 248 ? -13.08  -0.778  -13.289 1   56.01  ? 418 TYR B CD1 1 
ATOM   4395 C  CD2 . TYR B 2 248 ? -12.212 1.42    -13.699 1   54.04  ? 418 TYR B CD2 1 
ATOM   4396 C  CE1 . TYR B 2 248 ? -12.487 -0.794  -12.033 1   57.24  ? 418 TYR B CE1 1 
ATOM   4397 C  CE2 . TYR B 2 248 ? -11.627 1.418   -12.445 1   62.2   ? 418 TYR B CE2 1 
ATOM   4398 C  CZ  . TYR B 2 248 ? -11.757 0.31    -11.61  1   66.4   ? 418 TYR B CZ  1 
ATOM   4399 O  OH  . TYR B 2 248 ? -11.167 0.336   -10.37  1   71.25  ? 418 TYR B OH  1 
ATOM   4400 N  N   . HIS B 2 249 ? -12.76  -0.796  -18.918 1   51.64  ? 419 HIS B N   1 
ATOM   4401 C  CA  . HIS B 2 249 ? -13.214 -0.859  -20.306 1   55.68  ? 419 HIS B CA  1 
ATOM   4402 C  C   . HIS B 2 249 ? -13.852 0.461   -20.756 1   57.8   ? 419 HIS B C   1 
ATOM   4403 O  O   . HIS B 2 249 ? -14.609 0.465   -21.726 1   54.93  ? 419 HIS B O   1 
ATOM   4404 C  CB  . HIS B 2 249 ? -14.032 -2.135  -20.57  1   57.32  ? 419 HIS B CB  1 
ATOM   4405 C  CG  . HIS B 2 249 ? -13.307 -3.385  -20.159 1   63.74  ? 419 HIS B CG  1 
ATOM   4406 N  ND1 . HIS B 2 249 ? -13.451 -3.96   -18.904 1   65.9   ? 419 HIS B ND1 1 
ATOM   4407 C  CD2 . HIS B 2 249 ? -12.389 -4.128  -20.808 1   60.03  ? 419 HIS B CD2 1 
ATOM   4408 C  CE1 . HIS B 2 249 ? -12.657 -5.024  -18.807 1   66.63  ? 419 HIS B CE1 1 
ATOM   4409 N  NE2 . HIS B 2 249 ? -12.006 -5.142  -19.951 1   63.79  ? 419 HIS B NE2 1 
ATOM   4410 N  N   . GLY B 2 250 ? -13.508 1.573   -20.07  1   58.62  ? 420 GLY B N   1 
ATOM   4411 C  CA  . GLY B 2 250 ? -13.986 2.906   -20.4   1   58.79  ? 420 GLY B CA  1 
ATOM   4412 C  C   . GLY B 2 250 ? -15.509 2.963   -20.513 1   58.52  ? 420 GLY B C   1 
ATOM   4413 O  O   . GLY B 2 250 ? -16.028 3.758   -21.302 1   58.76  ? 420 GLY B O   1 
ATOM   4414 N  N   . VAL B 2 251 ? -16.205 2.184   -19.667 1   49.89  ? 421 VAL B N   1 
ATOM   4415 C  CA  . VAL B 2 251 ? -17.642 1.999   -19.806 1   50.63  ? 421 VAL B CA  1 
ATOM   4416 C  C   . VAL B 2 251 ? -18.426 3.29    -19.523 1   55.08  ? 421 VAL B C   1 
ATOM   4417 O  O   . VAL B 2 251 ? -19.594 3.378   -19.908 1   60.44  ? 421 VAL B O   1 
ATOM   4418 C  CB  . VAL B 2 251 ? -18.132 0.814   -18.96  1   46.03  ? 421 VAL B CB  1 
ATOM   4419 C  CG1 . VAL B 2 251 ? -17.527 -0.498  -19.454 1   43.06  ? 421 VAL B CG1 1 
ATOM   4420 C  CG2 . VAL B 2 251 ? -17.92  1.046   -17.471 1   44.86  ? 421 VAL B CG2 1 
ATOM   4421 N  N   . SER B 2 252 ? -17.803 4.279   -18.861 1   52.02  ? 422 SER B N   1 
ATOM   4422 C  CA  . SER B 2 252 ? -18.466 5.546   -18.57  1   52.26  ? 422 SER B CA  1 
ATOM   4423 C  C   . SER B 2 252 ? -18.672 6.361   -19.845 1   57.39  ? 422 SER B C   1 
ATOM   4424 O  O   . SER B 2 252 ? -19.442 7.313   -19.837 1   63.88  ? 422 SER B O   1 
ATOM   4425 C  CB  . SER B 2 252 ? -17.757 6.339   -17.482 1   48.96  ? 422 SER B CB  1 
ATOM   4426 O  OG  . SER B 2 252 ? -16.473 6.782   -17.874 1   61.53  ? 422 SER B OG  1 
ATOM   4427 N  N   . LEU B 2 253 ? -17.972 6.003   -20.93  1   60.62  ? 423 LEU B N   1 
ATOM   4428 C  CA  . LEU B 2 253 ? -18.103 6.684   -22.215 1   62.21  ? 423 LEU B CA  1 
ATOM   4429 C  C   . LEU B 2 253 ? -19.236 6.074   -23.044 1   64.62  ? 423 LEU B C   1 
ATOM   4430 O  O   . LEU B 2 253 ? -19.721 6.715   -23.981 1   63.68  ? 423 LEU B O   1 
ATOM   4431 C  CB  . LEU B 2 253 ? -16.765 6.641   -22.952 1   63.13  ? 423 LEU B CB  1 
ATOM   4432 C  CG  . LEU B 2 253 ? -15.562 7.172   -22.156 1   64.14  ? 423 LEU B CG  1 
ATOM   4433 C  CD1 . LEU B 2 253 ? -14.305 6.834   -22.938 1   65.78  ? 423 LEU B CD1 1 
ATOM   4434 C  CD2 . LEU B 2 253 ? -15.62  8.681   -21.852 1   61.21  ? 423 LEU B CD2 1 
ATOM   4435 N  N   . LEU B 2 254 ? -19.672 4.849   -22.682 1   61.26  ? 424 LEU B N   1 
ATOM   4436 C  CA  . LEU B 2 254 ? -20.811 4.221   -23.346 1   59.1   ? 424 LEU B CA  1 
ATOM   4437 C  C   . LEU B 2 254 ? -22.007 5.15    -23.191 1   66.39  ? 424 LEU B C   1 
ATOM   4438 O  O   . LEU B 2 254 ? -22.045 5.951   -22.252 1   72.2   ? 424 LEU B O   1 
ATOM   4439 C  CB  . LEU B 2 254 ? -21.131 2.836   -22.787 1   51.13  ? 424 LEU B CB  1 
ATOM   4440 C  CG  . LEU B 2 254 ? -20.115 1.735   -23.098 1   49.02  ? 424 LEU B CG  1 
ATOM   4441 C  CD1 . LEU B 2 254 ? -20.441 0.469   -22.343 1   42.86  ? 424 LEU B CD1 1 
ATOM   4442 C  CD2 . LEU B 2 254 ? -20.053 1.488   -24.62  1   47.73  ? 424 LEU B CD2 1 
ATOM   4443 N  N   . ASN B 2 255 ? -22.958 5.067   -24.131 1   70.33  ? 425 ASN B N   1 
ATOM   4444 C  CA  . ASN B 2 255 ? -24.125 5.939   -24.084 1   67.87  ? 425 ASN B CA  1 
ATOM   4445 C  C   . ASN B 2 255 ? -25.297 5.218   -23.429 1   64.56  ? 425 ASN B C   1 
ATOM   4446 O  O   . ASN B 2 255 ? -25.612 4.1     -23.814 1   64.63  ? 425 ASN B O   1 
ATOM   4447 C  CB  . ASN B 2 255 ? -24.567 6.402   -25.46  1   68.88  ? 425 ASN B CB  1 
ATOM   4448 C  CG  . ASN B 2 255 ? -23.69  7.483   -26.037 1   74.71  ? 425 ASN B CG  1 
ATOM   4449 O  OD1 . ASN B 2 255 ? -23.513 7.504   -27.259 1   81.1   ? 425 ASN B OD1 1 
ATOM   4450 N  ND2 . ASN B 2 255 ? -23.201 8.412   -25.22  1   71.97  ? 425 ASN B ND2 1 
ATOM   4451 N  N   . PRO B 2 256 ? -25.967 5.839   -22.433 1   62.66  ? 426 PRO B N   1 
ATOM   4452 C  CA  . PRO B 2 256 ? -27.181 5.26    -21.847 1   62.62  ? 426 PRO B CA  1 
ATOM   4453 C  C   . PRO B 2 256 ? -28.292 5.042   -22.884 1   66.52  ? 426 PRO B C   1 
ATOM   4454 O  O   . PRO B 2 256 ? -28.419 5.817   -23.837 1   62.12  ? 426 PRO B O   1 
ATOM   4455 C  CB  . PRO B 2 256 ? -27.583 6.281   -20.779 1   58.38  ? 426 PRO B CB  1 
ATOM   4456 C  CG  . PRO B 2 256 ? -26.889 7.557   -21.195 1   61.78  ? 426 PRO B CG  1 
ATOM   4457 C  CD  . PRO B 2 256 ? -25.586 7.135   -21.844 1   63.08  ? 426 PRO B CD  1 
ATOM   4458 N  N   . PRO B 2 257 ? -29.132 3.986   -22.734 1   64.14  ? 427 PRO B N   1 
ATOM   4459 C  CA  . PRO B 2 257 ? -30.305 3.802   -23.603 1   60.85  ? 427 PRO B CA  1 
ATOM   4460 C  C   . PRO B 2 257 ? -31.306 4.899   -23.248 1   64.37  ? 427 PRO B C   1 
ATOM   4461 O  O   . PRO B 2 257 ? -31.401 5.28    -22.082 1   62.15  ? 427 PRO B O   1 
ATOM   4462 C  CB  . PRO B 2 257 ? -30.816 2.412   -23.182 1   61.89  ? 427 PRO B CB  1 
ATOM   4463 C  CG  . PRO B 2 257 ? -30.355 2.27    -21.739 1   55.19  ? 427 PRO B CG  1 
ATOM   4464 C  CD  . PRO B 2 257 ? -28.991 2.94    -21.705 1   56.81  ? 427 PRO B CD  1 
ATOM   4465 N  N   . GLU B 2 258 ? -32.019 5.419   -24.252 1   69.74  ? 428 GLU B N   1 
ATOM   4466 C  CA  . GLU B 2 258 ? -32.978 6.489   -24.047 1   76.1   ? 428 GLU B CA  1 
ATOM   4467 C  C   . GLU B 2 258 ? -34.268 5.953   -23.411 1   77.22  ? 428 GLU B C   1 
ATOM   4468 O  O   . GLU B 2 258 ? -34.945 6.718   -22.719 1   71.59  ? 428 GLU B O   1 
ATOM   4469 C  CB  . GLU B 2 258 ? -33.247 7.191   -25.375 1   87.73  ? 428 GLU B CB  1 
ATOM   4470 C  CG  . GLU B 2 258 ? -32.145 8.135   -25.847 1   107.18 ? 428 GLU B CG  1 
ATOM   4471 C  CD  . GLU B 2 258 ? -32.419 8.657   -27.261 1   134.85 ? 428 GLU B CD  1 
ATOM   4472 O  OE1 . GLU B 2 258 ? -33.469 8.272   -27.833 1   137.83 ? 428 GLU B OE1 1 
ATOM   4473 O  OE2 . GLU B 2 258 ? -31.607 9.441   -27.817 1   149.99 ? 428 GLU B OE2 1 
ATOM   4474 N  N   . THR B 2 259 ? -34.598 4.656   -23.644 1   73.79  ? 429 THR B N   1 
ATOM   4475 C  CA  . THR B 2 259 ? -35.767 3.971   -23.084 1   74.35  ? 429 THR B CA  1 
ATOM   4476 C  C   . THR B 2 259 ? -35.446 2.509   -22.746 1   76.41  ? 429 THR B C   1 
ATOM   4477 O  O   . THR B 2 259 ? -34.54  1.914   -23.327 1   79.89  ? 429 THR B O   1 
ATOM   4478 C  CB  . THR B 2 259 ? -36.986 4.015   -24.015 1   75.1   ? 429 THR B CB  1 
ATOM   4479 O  OG1 . THR B 2 259 ? -36.728 3.058   -25.039 1   75.09  ? 429 THR B OG1 1 
ATOM   4480 C  CG2 . THR B 2 259 ? -37.322 5.387   -24.583 1   75.11  ? 429 THR B CG2 1 
ATOM   4481 N  N   . LEU B 2 260 ? -36.259 1.909   -21.858 1   76.33  ? 430 LEU B N   1 
ATOM   4482 C  CA  . LEU B 2 260 ? -36.068 0.547   -21.383 1   78.91  ? 430 LEU B CA  1 
ATOM   4483 C  C   . LEU B 2 260 ? -37.071 -0.434  -21.999 1   89.98  ? 430 LEU B C   1 
ATOM   4484 O  O   . LEU B 2 260 ? -36.809 -1.642  -22.015 1   92.64  ? 430 LEU B O   1 
ATOM   4485 C  CB  . LEU B 2 260 ? -36.194 0.523   -19.86  1   74.76  ? 430 LEU B CB  1 
ATOM   4486 C  CG  . LEU B 2 260 ? -35.151 1.294   -19.049 1   77.13  ? 430 LEU B CG  1 
ATOM   4487 C  CD1 . LEU B 2 260 ? -35.285 0.946   -17.58  1   75.8   ? 430 LEU B CD1 1 
ATOM   4488 C  CD2 . LEU B 2 260 ? -33.745 1.021   -19.512 1   76.31  ? 430 LEU B CD2 1 
ATOM   4489 N  N   . ASN B 2 261 ? -38.179 0.09    -22.51  1   97.15  ? 431 ASN B N   1 
ATOM   4490 C  CA  . ASN B 2 261 ? -39.239 -0.811  -23.033 1   104.96 ? 431 ASN B CA  1 
ATOM   4491 C  C   . ASN B 2 261 ? -39.591 -1.778  -21.902 1   104.21 ? 431 ASN B C   1 
ATOM   4492 O  O   . ASN B 2 261 ? -39.312 -2.988  -22.061 1   97.17  ? 431 ASN B O   1 
ATOM   4493 C  CB  . ASN B 2 261 ? -38.822 -1.467  -24.345 1   113.2  ? 431 ASN B CB  1 
ATOM   4494 C  CG  . ASN B 2 261 ? -38.198 -0.48   -25.302 1   116.63 ? 431 ASN B CG  1 
ATOM   4495 O  OD1 . ASN B 2 261 ? -37.097 -0.719  -25.808 1   117.28 ? 431 ASN B OD1 1 
ATOM   4496 N  ND2 . ASN B 2 261 ? -38.877 0.627   -25.563 1   110.46 ? 431 ASN B ND2 1 
ATOM   4497 N  N   . VAL B 2 262 ? -40.144 -1.245  -20.808 1   99.23  ? 432 VAL B N   1 
ATOM   4498 C  CA  . VAL B 2 262 ? -40.529 -2.071  -19.624 1   100.99 ? 432 VAL B CA  1 
ATOM   4499 C  C   . VAL B 2 262 ? -39.255 -2.496  -18.874 1   116.77 ? 432 VAL B C   1 
ATOM   4500 O  O   . VAL B 2 262 ? -39.021 -1.927  -17.786 1   125.84 ? 432 VAL B O   1 
ATOM   4501 C  CB  . VAL B 2 262 ? -41.409 -3.282  -19.999 1   92.23  ? 432 VAL B CB  1 
ATOM   4502 C  CG1 . VAL B 2 262 ? -41.691 -4.18   -18.8   1   81.25  ? 432 VAL B CG1 1 
ATOM   4503 C  CG2 . VAL B 2 262 ? -42.706 -2.852  -20.674 1   94.4   ? 432 VAL B CG2 1 
ATOM   4504 N  N   . SER C 1 4   ? -14.76  4.652   28.834  1   81.88  ? 0   SER C N   1 
ATOM   4505 C  CA  . SER C 1 4   ? -16.233 4.487   28.763  1   83.06  ? 0   SER C CA  1 
ATOM   4506 C  C   . SER C 1 4   ? -16.866 5.833   28.402  1   79.27  ? 0   SER C C   1 
ATOM   4507 O  O   . SER C 1 4   ? -17.63  5.896   27.421  1   71.19  ? 0   SER C O   1 
ATOM   4508 C  CB  . SER C 1 4   ? -16.766 3.962   30.066  1   76.77  ? 0   SER C CB  1 
ATOM   4509 O  OG  . SER C 1 4   ? -16.24  2.675   30.355  1   80.74  ? 0   SER C OG  1 
ATOM   4510 N  N   . MET C 1 5   ? -16.521 6.868   29.16   1   73.81  ? 1   MET C N   1 
ATOM   4511 C  CA  . MET C 1 5   ? -17.084 8.214   28.922  1   68.44  ? 1   MET C CA  1 
ATOM   4512 C  C   . MET C 1 5   ? -15.972 9.128   28.403  1   64.19  ? 1   MET C C   1 
ATOM   4513 O  O   . MET C 1 5   ? -16.19  10.34   28.349  1   65.54  ? 1   MET C O   1 
ATOM   4514 C  CB  . MET C 1 5   ? -17.652 8.757   30.235  1   70.33  ? 1   MET C CB  1 
ATOM   4515 C  CG  . MET C 1 5   ? -18.506 7.768   30.985  1   62.34  ? 1   MET C CG  1 
ATOM   4516 S  SD  . MET C 1 5   ? -20.111 7.71    30.173  1   68.7   ? 1   MET C SD  1 
ATOM   4517 C  CE  . MET C 1 5   ? -20.493 9.463   30.235  1   67.97  ? 1   MET C CE  1 
ATOM   4518 N  N   . GLU C 1 6   ? -14.847 8.551   27.991  1   67.65  ? 2   GLU C N   1 
ATOM   4519 C  CA  . GLU C 1 6   ? -13.684 9.353   27.533  1   72.7   ? 2   GLU C CA  1 
ATOM   4520 C  C   . GLU C 1 6   ? -14.041 10.178  26.295  1   68.57  ? 2   GLU C C   1 
ATOM   4521 O  O   . GLU C 1 6   ? -13.331 11.155  26.027  1   73.35  ? 2   GLU C O   1 
ATOM   4522 C  CB  . GLU C 1 6   ? -12.507 8.443   27.197  1   80.65  ? 2   GLU C CB  1 
ATOM   4523 C  CG  . GLU C 1 6   ? -11.156 9.021   27.606  1   103.63 ? 2   GLU C CG  1 
ATOM   4524 C  CD  . GLU C 1 6   ? -11.121 9.625   28.999  1   126.54 ? 2   GLU C CD  1 
ATOM   4525 O  OE1 . GLU C 1 6   ? -11.331 8.875   29.976  1   125.89 ? 2   GLU C OE1 1 
ATOM   4526 O  OE2 . GLU C 1 6   ? -10.876 10.845  29.108  1   132.76 ? 2   GLU C OE2 1 
ATOM   4527 N  N   . ASN C 1 7   ? -15.087 9.788   25.574  1   64.41  ? 3   ASN C N   1 
ATOM   4528 C  CA  . ASN C 1 7   ? -15.51  10.529  24.36   1   65.44  ? 3   ASN C CA  1 
ATOM   4529 C  C   . ASN C 1 7   ? -16.48  11.632  24.772  1   66.06  ? 3   ASN C C   1 
ATOM   4530 O  O   . ASN C 1 7   ? -16.981 12.34   23.889  1   71.98  ? 3   ASN C O   1 
ATOM   4531 C  CB  . ASN C 1 7   ? -16.128 9.598   23.328  1   64.3   ? 3   ASN C CB  1 
ATOM   4532 C  CG  . ASN C 1 7   ? -15.096 8.712   22.685  1   67.34  ? 3   ASN C CG  1 
ATOM   4533 O  OD1 . ASN C 1 7   ? -13.972 9.158   22.441  1   62.99  ? 3   ASN C OD1 1 
ATOM   4534 N  ND2 . ASN C 1 7   ? -15.455 7.468   22.411  1   63.25  ? 3   ASN C ND2 1 
ATOM   4535 N  N   . PHE C 1 8   ? -16.708 11.777  26.072  1   60.28  ? 4   PHE C N   1 
ATOM   4536 C  CA  . PHE C 1 8   ? -17.701 12.773  26.538  1   60.03  ? 4   PHE C CA  1 
ATOM   4537 C  C   . PHE C 1 8   ? -17.04  13.864  27.366  1   65.15  ? 4   PHE C C   1 
ATOM   4538 O  O   . PHE C 1 8   ? -16.447 13.553  28.398  1   72.5   ? 4   PHE C O   1 
ATOM   4539 C  CB  . PHE C 1 8   ? -18.814 12.027  27.275  1   55.08  ? 4   PHE C CB  1 
ATOM   4540 C  CG  . PHE C 1 8   ? -19.823 11.334  26.375  1   53.41  ? 4   PHE C CG  1 
ATOM   4541 C  CD1 . PHE C 1 8   ? -20.603 12.063  25.49   1   52.84  ? 4   PHE C CD1 1 
ATOM   4542 C  CD2 . PHE C 1 8   ? -19.985 9.956   26.419  1   55.49  ? 4   PHE C CD2 1 
ATOM   4543 C  CE1 . PHE C 1 8   ? -21.52  11.428  24.672  1   53.26  ? 4   PHE C CE1 1 
ATOM   4544 C  CE2 . PHE C 1 8   ? -20.904 9.328   25.599  1   57.29  ? 4   PHE C CE2 1 
ATOM   4545 C  CZ  . PHE C 1 8   ? -21.669 10.065  24.728  1   55.23  ? 4   PHE C CZ  1 
ATOM   4546 N  N   . GLN C 1 9   ? -17.077 15.103  26.888  1   65.12  ? 5   GLN C N   1 
ATOM   4547 C  CA  . GLN C 1 9   ? -16.616 16.277  27.612  1   65.56  ? 5   GLN C CA  1 
ATOM   4548 C  C   . GLN C 1 9   ? -17.815 16.967  28.26   1   61.4   ? 5   GLN C C   1 
ATOM   4549 O  O   . GLN C 1 9   ? -18.774 17.324  27.583  1   57.93  ? 5   GLN C O   1 
ATOM   4550 C  CB  . GLN C 1 9   ? -15.956 17.273  26.659  1   71.09  ? 5   GLN C CB  1 
ATOM   4551 C  CG  . GLN C 1 9   ? -15.329 18.482  27.346  1   85.72  ? 5   GLN C CG  1 
ATOM   4552 C  CD  . GLN C 1 9   ? -14.238 18.079  28.316  1   95.63  ? 5   GLN C CD  1 
ATOM   4553 O  OE1 . GLN C 1 9   ? -13.208 17.522  27.915  1   98.38  ? 5   GLN C OE1 1 
ATOM   4554 N  NE2 . GLN C 1 9   ? -14.466 18.316  29.604  1   93.88  ? 5   GLN C NE2 1 
ATOM   4555 N  N   . LYS C 1 10  ? -17.762 17.166  29.577  1   62.04  ? 6   LYS C N   1 
ATOM   4556 C  CA  . LYS C 1 10  ? -18.826 17.901  30.246  1   65.2   ? 6   LYS C CA  1 
ATOM   4557 C  C   . LYS C 1 10  ? -18.76  19.379  29.87   1   63.19  ? 6   LYS C C   1 
ATOM   4558 O  O   . LYS C 1 10  ? -17.675 19.925  29.713  1   62.71  ? 6   LYS C O   1 
ATOM   4559 C  CB  . LYS C 1 10  ? -18.635 17.784  31.756  1   74.76  ? 6   LYS C CB  1 
ATOM   4560 C  CG  . LYS C 1 10  ? -19.094 16.454  32.354  1   89.47  ? 6   LYS C CG  1 
ATOM   4561 C  CD  . LYS C 1 10  ? -18.851 16.304  33.857  1   99.68  ? 6   LYS C CD  1 
ATOM   4562 C  CE  . LYS C 1 10  ? -18.353 17.556  34.565  1   95.35  ? 6   LYS C CE  1 
ATOM   4563 N  NZ  . LYS C 1 10  ? -18.436 17.437  36.023  1   92.96  ? 6   LYS C NZ  1 
ATOM   4564 N  N   . VAL C 1 11  ? -19.929 20.009  29.736  1   61.56  ? 7   VAL C N   1 
ATOM   4565 C  CA  . VAL C 1 11  ? -20.029 21.439  29.504  1   66.11  ? 7   VAL C CA  1 
ATOM   4566 C  C   . VAL C 1 11  ? -20.53  22.108  30.793  1   67.4   ? 7   VAL C C   1 
ATOM   4567 O  O   . VAL C 1 11  ? -19.873 22.988  31.32   1   73.88  ? 7   VAL C O   1 
ATOM   4568 C  CB  . VAL C 1 11  ? -20.944 21.716  28.296  1   68.45  ? 7   VAL C CB  1 
ATOM   4569 C  CG1 . VAL C 1 11  ? -20.862 23.151  27.808  1   69.97  ? 7   VAL C CG1 1 
ATOM   4570 C  CG2 . VAL C 1 11  ? -20.659 20.756  27.148  1   68.6   ? 7   VAL C CG2 1 
ATOM   4571 N  N   . GLU C 1 12  ? -21.706 21.685  31.253  1   67.61  ? 8   GLU C N   1 
ATOM   4572 C  CA  . GLU C 1 12  ? -22.31  22.305  32.453  1   71.3   ? 8   GLU C CA  1 
ATOM   4573 C  C   . GLU C 1 12  ? -23.305 21.355  33.118  1   71.46  ? 8   GLU C C   1 
ATOM   4574 O  O   . GLU C 1 12  ? -23.683 20.354  32.493  1   67.12  ? 8   GLU C O   1 
ATOM   4575 C  CB  . GLU C 1 12  ? -23.095 23.554  32.07   1   72.99  ? 8   GLU C CB  1 
ATOM   4576 C  CG  . GLU C 1 12  ? -24.148 23.31   30.997  1   78.52  ? 8   GLU C CG  1 
ATOM   4577 C  CD  . GLU C 1 12  ? -24.676 24.62   30.453  1   86.74  ? 8   GLU C CD  1 
ATOM   4578 O  OE1 . GLU C 1 12  ? -23.923 25.293  29.721  1   82.15  ? 8   GLU C OE1 1 
ATOM   4579 O  OE2 . GLU C 1 12  ? -25.83  24.97   30.77   1   95.65  ? 8   GLU C OE2 1 
ATOM   4580 N  N   . LYS C 1 13  ? -23.705 21.674  34.348  1   75.44  ? 9   LYS C N   1 
ATOM   4581 C  CA  . LYS C 1 13  ? -24.743 20.875  35.04   1   82.94  ? 9   LYS C CA  1 
ATOM   4582 C  C   . LYS C 1 13  ? -26.103 21.452  34.643  1   80.27  ? 9   LYS C C   1 
ATOM   4583 O  O   . LYS C 1 13  ? -26.186 22.677  34.446  1   88.47  ? 9   LYS C O   1 
ATOM   4584 C  CB  . LYS C 1 13  ? -24.521 20.932  36.551  1   93.69  ? 9   LYS C CB  1 
ATOM   4585 C  CG  . LYS C 1 13  ? -25.462 20.104  37.411  1   113.19 ? 9   LYS C CG  1 
ATOM   4586 C  CD  . LYS C 1 13  ? -25.133 20.186  38.895  1   118.33 ? 9   LYS C CD  1 
ATOM   4587 C  CE  . LYS C 1 13  ? -26.063 19.396  39.755  1   118.45 ? 9   LYS C CE  1 
ATOM   4588 N  NZ  . LYS C 1 13  ? -25.707 19.507  41.172  1   118.26 ? 9   LYS C NZ  1 
ATOM   4589 N  N   . ILE C 1 14  ? -27.109 20.6    34.478  1   72.31  ? 10  ILE C N   1 
ATOM   4590 C  CA  . ILE C 1 14  ? -28.42  21.118  34.002  1   76.89  ? 10  ILE C CA  1 
ATOM   4591 C  C   . ILE C 1 14  ? -29.506 20.719  35.01   1   85.77  ? 10  ILE C C   1 
ATOM   4592 O  O   . ILE C 1 14  ? -30.667 21.118  34.809  1   98.23  ? 10  ILE C O   1 
ATOM   4593 C  CB  . ILE C 1 14  ? -28.72  20.62   32.576  1   76     ? 10  ILE C CB  1 
ATOM   4594 C  CG1 . ILE C 1 14  ? -28.728 19.105  32.477  1   74.69  ? 10  ILE C CG1 1 
ATOM   4595 C  CG2 . ILE C 1 14  ? -27.75  21.236  31.568  1   84.28  ? 10  ILE C CG2 1 
ATOM   4596 C  CD1 . ILE C 1 14  ? -28.694 18.595  31.05   1   68.3   ? 10  ILE C CD1 1 
ATOM   4597 N  N   . GLY C 1 15  ? -29.123 20.004  36.06   1   92.09  ? 11  GLY C N   1 
ATOM   4598 C  CA  . GLY C 1 15  ? -30.117 19.64   37.073  1   95.99  ? 11  GLY C CA  1 
ATOM   4599 C  C   . GLY C 1 15  ? -29.672 18.473  37.91   1   99.52  ? 11  GLY C C   1 
ATOM   4600 O  O   . GLY C 1 15  ? -28.624 17.888  37.602  1   100.16 ? 11  GLY C O   1 
ATOM   4601 N  N   . GLU C 1 16  ? -30.436 18.171  38.955  1   108.02 ? 12  GLU C N   1 
ATOM   4602 C  CA  . GLU C 1 16  ? -30.121 17.021  39.831  1   116.32 ? 12  GLU C CA  1 
ATOM   4603 C  C   . GLU C 1 16  ? -31.454 16.341  40.141  1   125.84 ? 12  GLU C C   1 
ATOM   4604 O  O   . GLU C 1 16  ? -32.178 16.832  41.024  1   135.26 ? 12  GLU C O   1 
ATOM   4605 C  CB  . GLU C 1 16  ? -29.397 17.471  41.098  1   111.51 ? 12  GLU C CB  1 
ATOM   4606 C  CG  . GLU C 1 16  ? -28.912 16.313  41.962  1   112.39 ? 12  GLU C CG  1 
ATOM   4607 C  CD  . GLU C 1 16  ? -27.539 16.556  42.556  1   123.53 ? 12  GLU C CD  1 
ATOM   4608 O  OE1 . GLU C 1 16  ? -27.213 17.734  42.811  1   125.02 ? 12  GLU C OE1 1 
ATOM   4609 O  OE2 . GLU C 1 16  ? -26.798 15.573  42.764  1   117.61 ? 12  GLU C OE2 1 
ATOM   4610 N  N   . GLY C 1 17  ? -31.771 15.273  39.415  1   126.64 ? 13  GLY C N   1 
ATOM   4611 C  CA  . GLY C 1 17  ? -33.07  14.604  39.601  1   136.1  ? 13  GLY C CA  1 
ATOM   4612 C  C   . GLY C 1 17  ? -33.01  13.553  40.684  1   146.16 ? 13  GLY C C   1 
ATOM   4613 O  O   . GLY C 1 17  ? -32.135 13.657  41.571  1   145.35 ? 13  GLY C O   1 
ATOM   4614 N  N   . THR C 1 18  ? -33.901 12.566  40.612  1   137.37 ? 14  THR C N   1 
ATOM   4615 C  CA  . THR C 1 18  ? -33.968 11.535  41.662  1   142    ? 14  THR C CA  1 
ATOM   4616 C  C   . THR C 1 18  ? -32.656 10.799  41.716  1   153.12 ? 14  THR C C   1 
ATOM   4617 O  O   . THR C 1 18  ? -32.149 10.583  42.838  1   156.68 ? 14  THR C O   1 
ATOM   4618 C  CB  . THR C 1 18  ? -35.122 10.592  41.33   1   129.92 ? 14  THR C CB  1 
ATOM   4619 O  OG1 . THR C 1 18  ? -34.64  9.726   40.309  1   133.23 ? 14  THR C OG1 1 
ATOM   4620 C  CG2 . THR C 1 18  ? -36.347 11.333  40.826  1   122.12 ? 14  THR C CG2 1 
ATOM   4621 N  N   . TYR C 1 19  ? -32.1   10.458  40.556  1   141.4  ? 15  TYR C N   1 
ATOM   4622 C  CA  . TYR C 1 19  ? -30.879 9.62    40.514  1   128.17 ? 15  TYR C CA  1 
ATOM   4623 C  C   . TYR C 1 19  ? -29.679 10.391  40.959  1   131.9  ? 15  TYR C C   1 
ATOM   4624 O  O   . TYR C 1 19  ? -28.809 9.841   41.667  1   125.74 ? 15  TYR C O   1 
ATOM   4625 C  CB  . TYR C 1 19  ? -30.739 9.29    39.036  1   118.33 ? 15  TYR C CB  1 
ATOM   4626 C  CG  . TYR C 1 19  ? -31.996 8.691   38.425  1   120.47 ? 15  TYR C CG  1 
ATOM   4627 C  CD1 . TYR C 1 19  ? -32.388 7.395   38.726  1   111.88 ? 15  TYR C CD1 1 
ATOM   4628 C  CD2 . TYR C 1 19  ? -32.787 9.424   37.553  1   124.03 ? 15  TYR C CD2 1 
ATOM   4629 C  CE1 . TYR C 1 19  ? -33.522 6.839   38.162  1   102.78 ? 15  TYR C CE1 1 
ATOM   4630 C  CE2 . TYR C 1 19  ? -33.93  8.884   36.994  1   111.01 ? 15  TYR C CE2 1 
ATOM   4631 C  CZ  . TYR C 1 19  ? -34.296 7.586   37.297  1   97.39  ? 15  TYR C CZ  1 
ATOM   4632 O  OH  . TYR C 1 19  ? -35.416 7.046   36.744  1   89.68  ? 15  TYR C OH  1 
ATOM   4633 N  N   . GLY C 1 20  ? -29.602 11.643  40.528  1   126.67 ? 16  GLY C N   1 
ATOM   4634 C  CA  . GLY C 1 20  ? -28.415 12.444  40.841  1   107.52 ? 16  GLY C CA  1 
ATOM   4635 C  C   . GLY C 1 20  ? -28.301 13.578  39.859  1   107.4  ? 16  GLY C C   1 
ATOM   4636 O  O   . GLY C 1 20  ? -29.348 14.007  39.347  1   116.84 ? 16  GLY C O   1 
ATOM   4637 N  N   . VAL C 1 21  ? -27.079 13.973  39.524  1   99.2   ? 17  VAL C N   1 
ATOM   4638 C  CA  . VAL C 1 21  ? -26.888 15.173  38.667  1   91.12  ? 17  VAL C CA  1 
ATOM   4639 C  C   . VAL C 1 21  ? -27.093 14.853  37.181  1   89.83  ? 17  VAL C C   1 
ATOM   4640 O  O   . VAL C 1 21  ? -26.721 13.742  36.756  1   76.41  ? 17  VAL C O   1 
ATOM   4641 C  CB  . VAL C 1 21  ? -25.474 15.709  38.941  1   90.28  ? 17  VAL C CB  1 
ATOM   4642 C  CG1 . VAL C 1 21  ? -24.4   14.705  38.545  1   90.61  ? 17  VAL C CG1 1 
ATOM   4643 C  CG2 . VAL C 1 21  ? -25.237 17.048  38.264  1   100.63 ? 17  VAL C CG2 1 
ATOM   4644 N  N   . VAL C 1 22  ? -27.704 15.782  36.444  1   78.4   ? 18  VAL C N   1 
ATOM   4645 C  CA  . VAL C 1 22  ? -27.832 15.634  34.968  1   65.23  ? 18  VAL C CA  1 
ATOM   4646 C  C   . VAL C 1 22  ? -26.886 16.686  34.379  1   65.21  ? 18  VAL C C   1 
ATOM   4647 O  O   . VAL C 1 22  ? -26.937 17.84   34.837  1   63.42  ? 18  VAL C O   1 
ATOM   4648 C  CB  . VAL C 1 22  ? -29.27  15.812  34.454  1   59.37  ? 18  VAL C CB  1 
ATOM   4649 C  CG1 . VAL C 1 22  ? -29.419 15.346  33.012  1   60.39  ? 18  VAL C CG1 1 
ATOM   4650 C  CG2 . VAL C 1 22  ? -30.278 15.108  35.352  1   62.43  ? 18  VAL C CG2 1 
ATOM   4651 N  N   . TYR C 1 23  ? -26.032 16.288  33.441  1   63.06  ? 19  TYR C N   1 
ATOM   4652 C  CA  . TYR C 1 23  ? -25.028 17.226  32.892  1   63.12  ? 19  TYR C CA  1 
ATOM   4653 C  C   . TYR C 1 23  ? -25.194 17.396  31.409  1   58.02  ? 19  TYR C C   1 
ATOM   4654 O  O   . TYR C 1 23  ? -25.605 16.443  30.739  1   53.59  ? 19  TYR C O   1 
ATOM   4655 C  CB  . TYR C 1 23  ? -23.625 16.638  32.997  1   66.68  ? 19  TYR C CB  1 
ATOM   4656 C  CG  . TYR C 1 23  ? -22.997 16.483  34.373  1   87.84  ? 19  TYR C CG  1 
ATOM   4657 C  CD1 . TYR C 1 23  ? -22.849 15.229  34.949  1   103.62 ? 19  TYR C CD1 1 
ATOM   4658 C  CD2 . TYR C 1 23  ? -22.506 17.581  35.065  1   90.68  ? 19  TYR C CD2 1 
ATOM   4659 C  CE1 . TYR C 1 23  ? -22.253 15.072  36.188  1   109.7  ? 19  TYR C CE1 1 
ATOM   4660 C  CE2 . TYR C 1 23  ? -21.911 17.437  36.307  1   92.7   ? 19  TYR C CE2 1 
ATOM   4661 C  CZ  . TYR C 1 23  ? -21.783 16.18   36.868  1   104.59 ? 19  TYR C CZ  1 
ATOM   4662 O  OH  . TYR C 1 23  ? -21.204 16.031  38.093  1   122.31 ? 19  TYR C OH  1 
ATOM   4663 N  N   . LYS C 1 24  ? -24.892 18.59   30.905  1   56.16  ? 20  LYS C N   1 
ATOM   4664 C  CA  . LYS C 1 24  ? -24.871 18.804  29.441  1   53.83  ? 20  LYS C CA  1 
ATOM   4665 C  C   . LYS C 1 24  ? -23.476 18.376  29.012  1   55.84  ? 20  LYS C C   1 
ATOM   4666 O  O   . LYS C 1 24  ? -22.514 18.706  29.725  1   58.01  ? 20  LYS C O   1 
ATOM   4667 C  CB  . LYS C 1 24  ? -25.127 20.252  29.027  1   55.72  ? 20  LYS C CB  1 
ATOM   4668 C  CG  . LYS C 1 24  ? -24.863 20.598  27.576  1   55.89  ? 20  LYS C CG  1 
ATOM   4669 C  CD  . LYS C 1 24  ? -24.923 22.103  27.359  1   54.97  ? 20  LYS C CD  1 
ATOM   4670 C  CE  . LYS C 1 24  ? -25.064 22.474  25.925  1   56.6   ? 20  LYS C CE  1 
ATOM   4671 N  NZ  . LYS C 1 24  ? -25.296 23.911  25.774  1   61.82  ? 20  LYS C NZ  1 
ATOM   4672 N  N   . ALA C 1 25  ? -23.377 17.664  27.902  1   55.2   ? 21  ALA C N   1 
ATOM   4673 C  CA  . ALA C 1 25  ? -22.097 17.097  27.511  1   55.44  ? 21  ALA C CA  1 
ATOM   4674 C  C   . ALA C 1 25  ? -22.018 17.064  25.988  1   54.55  ? 21  ALA C C   1 
ATOM   4675 O  O   . ALA C 1 25  ? -23.037 17.212  25.298  1   51.74  ? 21  ALA C O   1 
ATOM   4676 C  CB  . ALA C 1 25  ? -21.934 15.716  28.122  1   52.35  ? 21  ALA C CB  1 
ATOM   4677 N  N   . ARG C 1 26  ? -20.793 16.877  25.493  1   53.16  ? 22  ARG C N   1 
ATOM   4678 C  CA  . ARG C 1 26  ? -20.516 16.916  24.075  1   54.47  ? 22  ARG C CA  1 
ATOM   4679 C  C   . ARG C 1 26  ? -19.675 15.697  23.729  1   56.23  ? 22  ARG C C   1 
ATOM   4680 O  O   . ARG C 1 26  ? -18.639 15.458  24.355  1   54.42  ? 22  ARG C O   1 
ATOM   4681 C  CB  . ARG C 1 26  ? -19.721 18.187  23.78   1   63.27  ? 22  ARG C CB  1 
ATOM   4682 C  CG  . ARG C 1 26  ? -19.694 18.649  22.331  1   74.7   ? 22  ARG C CG  1 
ATOM   4683 C  CD  . ARG C 1 26  ? -18.918 19.974  22.188  1   81.19  ? 22  ARG C CD  1 
ATOM   4684 N  NE  . ARG C 1 26  ? -17.572 19.597  21.727  1   97.21  ? 22  ARG C NE  1 
ATOM   4685 C  CZ  . ARG C 1 26  ? -16.452 19.489  22.453  1   97.46  ? 22  ARG C CZ  1 
ATOM   4686 N  NH1 . ARG C 1 26  ? -16.455 19.837  23.727  1   94.74  ? 22  ARG C NH1 1 
ATOM   4687 N  NH2 . ARG C 1 26  ? -15.349 19.006  21.907  1   95.57  ? 22  ARG C NH2 1 
ATOM   4688 N  N   . ASN C 1 27  ? -20.143 14.941  22.721  1   54.6   ? 23  ASN C N   1 
ATOM   4689 C  CA  . ASN C 1 27  ? -19.38  13.846  22.137  1   53.71  ? 23  ASN C CA  1 
ATOM   4690 C  C   . ASN C 1 27  ? -18.191 14.398  21.349  1   55.2   ? 23  ASN C C   1 
ATOM   4691 O  O   . ASN C 1 27  ? -18.371 15.071  20.336  1   57.37  ? 23  ASN C O   1 
ATOM   4692 C  CB  . ASN C 1 27  ? -20.274 12.99   21.248  1   53     ? 23  ASN C CB  1 
ATOM   4693 C  CG  . ASN C 1 27  ? -19.614 11.693  20.817  1   53.83  ? 23  ASN C CG  1 
ATOM   4694 O  OD1 . ASN C 1 27  ? -18.482 11.704  20.299  1   50.19  ? 23  ASN C OD1 1 
ATOM   4695 N  ND2 . ASN C 1 27  ? -20.308 10.575  21.032  1   49.2   ? 23  ASN C ND2 1 
ATOM   4696 N  N   . LYS C 1 28  ? -16.971 14.098  21.796  1   56.48  ? 24  LYS C N   1 
ATOM   4697 C  CA  . LYS C 1 28  ? -15.778 14.735  21.249  1   63.04  ? 24  LYS C CA  1 
ATOM   4698 C  C   . LYS C 1 28  ? -15.467 14.246  19.829  1   64.52  ? 24  LYS C C   1 
ATOM   4699 O  O   . LYS C 1 28  ? -14.686 14.871  19.098  1   67.81  ? 24  LYS C O   1 
ATOM   4700 C  CB  . LYS C 1 28  ? -14.542 14.434  22.105  1   66.72  ? 24  LYS C CB  1 
ATOM   4701 C  CG  . LYS C 1 28  ? -14.51  14.927  23.537  1   68.86  ? 24  LYS C CG  1 
ATOM   4702 C  CD  . LYS C 1 28  ? -13.205 14.543  24.23   1   75.61  ? 24  LYS C CD  1 
ATOM   4703 C  CE  . LYS C 1 28  ? -13.409 14.261  25.69   1   79.03  ? 24  LYS C CE  1 
ATOM   4704 N  NZ  . LYS C 1 28  ? -12.189 13.912  26.423  1   79.2   ? 24  LYS C NZ  1 
ATOM   4705 N  N   . LEU C 1 29  ? -16.043 13.098  19.451  1   61.46  ? 25  LEU C N   1 
ATOM   4706 C  CA  . LEU C 1 29  ? -15.747 12.498  18.164  1   58.08  ? 25  LEU C CA  1 
ATOM   4707 C  C   . LEU C 1 29  ? -16.805 12.881  17.121  1   58.51  ? 25  LEU C C   1 
ATOM   4708 O  O   . LEU C 1 29  ? -16.443 13.119  15.972  1   62.04  ? 25  LEU C O   1 
ATOM   4709 C  CB  . LEU C 1 29  ? -15.583 10.996  18.363  1   53.29  ? 25  LEU C CB  1 
ATOM   4710 C  CG  . LEU C 1 29  ? -14.216 10.545  18.891  1   51.24  ? 25  LEU C CG  1 
ATOM   4711 C  CD1 . LEU C 1 29  ? -14.237 9.032   19.113  1   48.69  ? 25  LEU C CD1 1 
ATOM   4712 C  CD2 . LEU C 1 29  ? -13.096 10.965  17.964  1   51.1   ? 25  LEU C CD2 1 
ATOM   4713 N  N   . THR C 1 30  ? -18.081 12.989  17.525  1   53.54  ? 26  THR C N   1 
ATOM   4714 C  CA  . THR C 1 30  ? -19.165 13.284  16.603  1   53.88  ? 26  THR C CA  1 
ATOM   4715 C  C   . THR C 1 30  ? -19.635 14.739  16.68   1   56.41  ? 26  THR C C   1 
ATOM   4716 O  O   . THR C 1 30  ? -20.276 15.218  15.746  1   57.1   ? 26  THR C O   1 
ATOM   4717 C  CB  . THR C 1 30  ? -20.338 12.332  16.823  1   54.41  ? 26  THR C CB  1 
ATOM   4718 O  OG1 . THR C 1 30  ? -20.955 12.716  18.048  1   51.33  ? 26  THR C OG1 1 
ATOM   4719 C  CG2 . THR C 1 30  ? -19.932 10.864  16.837  1   53.55  ? 26  THR C CG2 1 
ATOM   4720 N  N   . GLY C 1 31  ? -19.353 15.454  17.781  1   58.02  ? 27  GLY C N   1 
ATOM   4721 C  CA  . GLY C 1 31  ? -19.89  16.801  17.971  1   56.85  ? 27  GLY C CA  1 
ATOM   4722 C  C   . GLY C 1 31  ? -21.299 16.819  18.587  1   57.97  ? 27  GLY C C   1 
ATOM   4723 O  O   . GLY C 1 31  ? -21.774 17.866  19.034  1   62.64  ? 27  GLY C O   1 
ATOM   4724 N  N   . GLU C 1 32  ? -21.984 15.666  18.618  1   54.83  ? 28  GLU C N   1 
ATOM   4725 C  CA  . GLU C 1 32  ? -23.295 15.57   19.247  1   55.34  ? 28  GLU C CA  1 
ATOM   4726 C  C   . GLU C 1 32  ? -23.23  16.089  20.686  1   57.86  ? 28  GLU C C   1 
ATOM   4727 O  O   . GLU C 1 32  ? -22.305 15.747  21.424  1   61.5   ? 28  GLU C O   1 
ATOM   4728 C  CB  . GLU C 1 32  ? -23.753 14.114  19.261  1   52.31  ? 28  GLU C CB  1 
ATOM   4729 C  CG  . GLU C 1 32  ? -25.19  13.903  19.729  1   49.47  ? 28  GLU C CG  1 
ATOM   4730 C  CD  . GLU C 1 32  ? -25.598 12.424  19.711  1   55.99  ? 28  GLU C CD  1 
ATOM   4731 O  OE1 . GLU C 1 32  ? -24.766 11.511  19.989  1   49.84  ? 28  GLU C OE1 1 
ATOM   4732 O  OE2 . GLU C 1 32  ? -26.806 12.174  19.461  1   59.62  ? 28  GLU C OE2 1 
ATOM   4733 N  N   . VAL C 1 33  ? -24.196 16.956  21.043  1   53.63  ? 29  VAL C N   1 
ATOM   4734 C  CA  . VAL C 1 33  ? -24.424 17.47   22.388  1   49.51  ? 29  VAL C CA  1 
ATOM   4735 C  C   . VAL C 1 33  ? -25.486 16.583  23.042  1   47.68  ? 29  VAL C C   1 
ATOM   4736 O  O   . VAL C 1 33  ? -26.507 16.308  22.431  1   49.59  ? 29  VAL C O   1 
ATOM   4737 C  CB  . VAL C 1 33  ? -24.893 18.943  22.333  1   48.99  ? 29  VAL C CB  1 
ATOM   4738 C  CG1 . VAL C 1 33  ? -25.177 19.491  23.725  1   47.58  ? 29  VAL C CG1 1 
ATOM   4739 C  CG2 . VAL C 1 33  ? -23.939 19.87   21.56   1   47.16  ? 29  VAL C CG2 1 
ATOM   4740 N  N   . VAL C 1 34  ? -25.255 16.128  24.279  1   44.31  ? 30  VAL C N   1 
ATOM   4741 C  CA  . VAL C 1 34  ? -26.167 15.201  24.934  1   43.72  ? 30  VAL C CA  1 
ATOM   4742 C  C   . VAL C 1 34  ? -26.427 15.679  26.368  1   45.97  ? 30  VAL C C   1 
ATOM   4743 O  O   . VAL C 1 34  ? -25.69  16.501  26.903  1   52.02  ? 30  VAL C O   1 
ATOM   4744 C  CB  . VAL C 1 34  ? -25.581 13.773  24.916  1   41.58  ? 30  VAL C CB  1 
ATOM   4745 C  CG1 . VAL C 1 34  ? -25.264 13.298  23.509  1   38.82  ? 30  VAL C CG1 1 
ATOM   4746 C  CG2 . VAL C 1 34  ? -24.313 13.647  25.75   1   42.65  ? 30  VAL C CG2 1 
ATOM   4747 N  N   . ALA C 1 35  ? -27.49  15.179  26.994  1   45.93  ? 31  ALA C N   1 
ATOM   4748 C  CA  . ALA C 1 35  ? -27.61  15.234  28.447  1   46.37  ? 31  ALA C CA  1 
ATOM   4749 C  C   . ALA C 1 35  ? -27.191 13.872  28.99   1   48.64  ? 31  ALA C C   1 
ATOM   4750 O  O   . ALA C 1 35  ? -27.59  12.864  28.426  1   52.97  ? 31  ALA C O   1 
ATOM   4751 C  CB  . ALA C 1 35  ? -29.039 15.559  28.856  1   39.11  ? 31  ALA C CB  1 
ATOM   4752 N  N   . LEU C 1 36  ? -26.378 13.844  30.052  1   51.11  ? 32  LEU C N   1 
ATOM   4753 C  CA  . LEU C 1 36  ? -25.946 12.625  30.719  1   49.87  ? 32  LEU C CA  1 
ATOM   4754 C  C   . LEU C 1 36  ? -26.619 12.533  32.087  1   53.69  ? 32  LEU C C   1 
ATOM   4755 O  O   . LEU C 1 36  ? -26.406 13.399  32.93   1   60.03  ? 32  LEU C O   1 
ATOM   4756 C  CB  . LEU C 1 36  ? -24.429 12.692  30.895  1   46.86  ? 32  LEU C CB  1 
ATOM   4757 C  CG  . LEU C 1 36  ? -23.6   12.705  29.61   1   49.9   ? 32  LEU C CG  1 
ATOM   4758 C  CD1 . LEU C 1 36  ? -22.123 12.575  29.941  1   50.02  ? 32  LEU C CD1 1 
ATOM   4759 C  CD2 . LEU C 1 36  ? -24.011 11.589  28.676  1   50.52  ? 32  LEU C CD2 1 
ATOM   4760 N  N   . LYS C 1 37  ? -27.414 11.485  32.32   1   55.75  ? 33  LYS C N   1 
ATOM   4761 C  CA  . LYS C 1 37  ? -27.977 11.238  33.639  1   50.52  ? 33  LYS C CA  1 
ATOM   4762 C  C   . LYS C 1 37  ? -27.057 10.227  34.315  1   52.33  ? 33  LYS C C   1 
ATOM   4763 O  O   . LYS C 1 37  ? -26.86  9.142   33.793  1   55.82  ? 33  LYS C O   1 
ATOM   4764 C  CB  . LYS C 1 37  ? -29.415 10.731  33.482  1   50.59  ? 33  LYS C CB  1 
ATOM   4765 C  CG  . LYS C 1 37  ? -30.37  11.001  34.631  1   53.79  ? 33  LYS C CG  1 
ATOM   4766 C  CD  . LYS C 1 37  ? -31.815 10.511  34.483  1   54.45  ? 33  LYS C CD  1 
ATOM   4767 C  CE  . LYS C 1 37  ? -32.746 11.441  33.76   1   58.91  ? 33  LYS C CE  1 
ATOM   4768 N  NZ  . LYS C 1 37  ? -34.17  11.085  33.844  1   62.7   ? 33  LYS C NZ  1 
ATOM   4769 N  N   . LYS C 1 38  ? -26.457 10.616  35.442  1   55.46  ? 34  LYS C N   1 
ATOM   4770 C  CA  . LYS C 1 38  ? -25.576 9.756   36.21   1   58.59  ? 34  LYS C CA  1 
ATOM   4771 C  C   . LYS C 1 38  ? -26.368 9.162   37.374  1   65     ? 34  LYS C C   1 
ATOM   4772 O  O   . LYS C 1 38  ? -26.981 9.9     38.154  1   75.56  ? 34  LYS C O   1 
ATOM   4773 C  CB  . LYS C 1 38  ? -24.36  10.545  36.696  1   59.05  ? 34  LYS C CB  1 
ATOM   4774 C  CG  . LYS C 1 38  ? -23.413 9.743   37.572  1   68.06  ? 34  LYS C CG  1 
ATOM   4775 C  CD  . LYS C 1 38  ? -22.036 10.363  37.773  1   72.45  ? 34  LYS C CD  1 
ATOM   4776 C  CE  . LYS C 1 38  ? -21.788 10.833  39.164  1   83.67  ? 34  LYS C CE  1 
ATOM   4777 N  NZ  . LYS C 1 38  ? -20.409 11.335  39.254  1   95.37  ? 34  LYS C NZ  1 
ATOM   4778 N  N   . ILE C 1 39  ? -26.376 7.82    37.448  1   63.23  ? 35  ILE C N   1 
ATOM   4779 C  CA  . ILE C 1 39  ? -27.14  7.079   38.445  1   59.73  ? 35  ILE C CA  1 
ATOM   4780 C  C   . ILE C 1 39  ? -26.165 6.252   39.275  1   65.16  ? 35  ILE C C   1 
ATOM   4781 O  O   . ILE C 1 39  ? -25.557 5.324   38.749  1   66.92  ? 35  ILE C O   1 
ATOM   4782 C  CB  . ILE C 1 39  ? -28.219 6.206   37.778  1   55.53  ? 35  ILE C CB  1 
ATOM   4783 C  CG1 . ILE C 1 39  ? -29.268 7.071   37.118  1   53.8   ? 35  ILE C CG1 1 
ATOM   4784 C  CG2 . ILE C 1 39  ? -28.854 5.24    38.776  1   53.43  ? 35  ILE C CG2 1 
ATOM   4785 C  CD1 . ILE C 1 39  ? -30.252 6.334   36.238  1   55.14  ? 35  ILE C CD1 1 
ATOM   4786 N  N   . ARG C 1 40  ? -26.076 6.584   40.561  1   72.43  ? 36  ARG C N   1 
ATOM   4787 C  CA  . ARG C 1 40  ? -25.181 5.836   41.471  1   81.85  ? 36  ARG C CA  1 
ATOM   4788 C  C   . ARG C 1 40  ? -25.776 4.463   41.771  1   81.52  ? 36  ARG C C   1 
ATOM   4789 O  O   . ARG C 1 40  ? -26.967 4.387   42.123  1   80.67  ? 36  ARG C O   1 
ATOM   4790 C  CB  . ARG C 1 40  ? -24.961 6.574   42.792  1   99.18  ? 36  ARG C CB  1 
ATOM   4791 C  CG  . ARG C 1 40  ? -23.863 7.625   42.734  1   120.88 ? 36  ARG C CG  1 
ATOM   4792 C  CD  . ARG C 1 40  ? -22.526 7.056   42.292  1   138.01 ? 36  ARG C CD  1 
ATOM   4793 N  NE  . ARG C 1 40  ? -21.625 8.122   41.841  1   150.85 ? 36  ARG C NE  1 
ATOM   4794 C  CZ  . ARG C 1 40  ? -20.379 8.291   42.263  1   146.44 ? 36  ARG C CZ  1 
ATOM   4795 N  NH1 . ARG C 1 40  ? -19.866 7.465   43.156  1   131.5  ? 36  ARG C NH1 1 
ATOM   4796 N  NH2 . ARG C 1 40  ? -19.648 9.282   41.786  1   146.75 ? 36  ARG C NH2 1 
ATOM   4797 N  N   . LEU C 1 41  ? -24.966 3.428   41.621  1   71.74  ? 37  LEU C N   1 
ATOM   4798 C  CA  . LEU C 1 41  ? -25.368 2.062   41.932  1   68.22  ? 37  LEU C CA  1 
ATOM   4799 C  C   . LEU C 1 41  ? -25.001 1.729   43.385  1   74.77  ? 37  LEU C C   1 
ATOM   4800 O  O   . LEU C 1 41  ? -23.84  1.823   43.806  1   73.89  ? 37  LEU C O   1 
ATOM   4801 C  CB  . LEU C 1 41  ? -24.704 1.09    40.96   1   62.06  ? 37  LEU C CB  1 
ATOM   4802 C  CG  . LEU C 1 41  ? -25.139 1.172   39.497  1   57.11  ? 37  LEU C CG  1 
ATOM   4803 C  CD1 . LEU C 1 41  ? -24.68  -0.034  38.696  1   52.85  ? 37  LEU C CD1 1 
ATOM   4804 C  CD2 . LEU C 1 41  ? -26.631 1.326   39.407  1   55.82  ? 37  LEU C CD2 1 
ATOM   4805 N  N   . ASP C 1 42  ? -26.015 1.319   44.154  1   73.99  ? 38  ASP C N   1 
ATOM   4806 C  CA  . ASP C 1 42  ? -25.844 0.887   45.538  1   79.84  ? 38  ASP C CA  1 
ATOM   4807 C  C   . ASP C 1 42  ? -25.286 -0.544  45.57   1   69.15  ? 38  ASP C C   1 
ATOM   4808 O  O   . ASP C 1 42  ? -26.042 -1.492  45.796  1   71.82  ? 38  ASP C O   1 
ATOM   4809 C  CB  . ASP C 1 42  ? -27.173 1.023   46.284  1   88.61  ? 38  ASP C CB  1 
ATOM   4810 C  CG  . ASP C 1 42  ? -27.773 2.424   46.337  1   89.51  ? 38  ASP C CG  1 
ATOM   4811 O  OD1 . ASP C 1 42  ? -26.969 3.372   46.276  1   96.56  ? 38  ASP C OD1 1 
ATOM   4812 O  OD2 . ASP C 1 42  ? -29.032 2.556   46.4    1   85.61  ? 38  ASP C OD2 1 
ATOM   4813 N  N   . THR C 1 43  ? -23.968 -0.708  45.371  1   60.11  ? 39  THR C N   1 
ATOM   4814 C  CA  . THR C 1 43  ? -23.384 -2.013  45.041  1   59.52  ? 39  THR C CA  1 
ATOM   4815 C  C   . THR C 1 43  ? -23.248 -2.983  46.228  1   62.23  ? 39  THR C C   1 
ATOM   4816 O  O   . THR C 1 43  ? -22.949 -4.166  46.041  1   62.86  ? 39  THR C O   1 
ATOM   4817 C  CB  . THR C 1 43  ? -22.048 -1.852  44.313  1   59.18  ? 39  THR C CB  1 
ATOM   4818 O  OG1 . THR C 1 43  ? -21.152 -1.061  45.078  1   64     ? 39  THR C OG1 1 
ATOM   4819 C  CG2 . THR C 1 43  ? -22.182 -1.142  42.978  1   55.68  ? 39  THR C CG2 1 
ATOM   4820 N  N   . GLU C 1 44  ? -23.429 -2.493  47.461  1   64.28  ? 40  GLU C N   1 
ATOM   4821 C  CA  . GLU C 1 44  ? -23.333 -3.348  48.628  1   66.83  ? 40  GLU C CA  1 
ATOM   4822 C  C   . GLU C 1 44  ? -24.639 -3.355  49.418  1   67.7   ? 40  GLU C C   1 
ATOM   4823 O  O   . GLU C 1 44  ? -24.694 -4      50.461  1   75.43  ? 40  GLU C O   1 
ATOM   4824 C  CB  . GLU C 1 44  ? -22.211 -2.898  49.559  1   71.61  ? 40  GLU C CB  1 
ATOM   4825 C  CG  . GLU C 1 44  ? -20.804 -3.082  48.997  1   75.81  ? 40  GLU C CG  1 
ATOM   4826 C  CD  . GLU C 1 44  ? -20.409 -2.035  47.963  1   75.26  ? 40  GLU C CD  1 
ATOM   4827 O  OE1 . GLU C 1 44  ? -19.817 -2.443  46.936  1   81.65  ? 40  GLU C OE1 1 
ATOM   4828 O  OE2 . GLU C 1 44  ? -20.683 -0.828  48.151  1   70.77  ? 40  GLU C OE2 1 
ATOM   4829 N  N   . THR C 1 45  ? -25.661 -2.638  48.938  1   63.24  ? 41  THR C N   1 
ATOM   4830 C  CA  . THR C 1 45  ? -26.93  -2.51   49.638  1   64.05  ? 41  THR C CA  1 
ATOM   4831 C  C   . THR C 1 45  ? -28.068 -2.892  48.697  1   61.38  ? 41  THR C C   1 
ATOM   4832 O  O   . THR C 1 45  ? -28.434 -4.06   48.697  1   66.82  ? 41  THR C O   1 
ATOM   4833 C  CB  . THR C 1 45  ? -27.108 -1.137  50.302  1   65.1   ? 41  THR C CB  1 
ATOM   4834 O  OG1 . THR C 1 45  ? -26.736 -0.09   49.403  1   66.05  ? 41  THR C OG1 1 
ATOM   4835 C  CG2 . THR C 1 45  ? -26.283 -1.011  51.569  1   68.32  ? 41  THR C CG2 1 
ATOM   4836 N  N   . GLU C 1 46  ? -28.543 -1.945  47.872  1   56.29  ? 42  GLU C N   1 
ATOM   4837 C  CA  . GLU C 1 46  ? -29.847 -2.011  47.219  1   56.49  ? 42  GLU C CA  1 
ATOM   4838 C  C   . GLU C 1 46  ? -29.776 -2.236  45.702  1   52.99  ? 42  GLU C C   1 
ATOM   4839 O  O   . GLU C 1 46  ? -30.799 -2.52   45.098  1   52.79  ? 42  GLU C O   1 
ATOM   4840 C  CB  . GLU C 1 46  ? -30.739 -0.826  47.611  1   56.68  ? 42  GLU C CB  1 
ATOM   4841 C  CG  . GLU C 1 46  ? -31.286 -0.951  49.037  1   64.29  ? 42  GLU C CG  1 
ATOM   4842 C  CD  . GLU C 1 46  ? -31.689 -2.34   49.584  1   76.5   ? 42  GLU C CD  1 
ATOM   4843 O  OE1 . GLU C 1 46  ? -32.562 -3.045  49.007  1   75.57  ? 42  GLU C OE1 1 
ATOM   4844 O  OE2 . GLU C 1 46  ? -31.163 -2.739  50.656  1   86.5   ? 42  GLU C OE2 1 
ATOM   4845 N  N   . GLY C 1 47  ? -28.6   -2.1    45.074  1   52.02  ? 43  GLY C N   1 
ATOM   4846 C  CA  . GLY C 1 47  ? -28.422 -2.431  43.665  1   48.74  ? 43  GLY C CA  1 
ATOM   4847 C  C   . GLY C 1 47  ? -28.907 -1.313  42.749  1   48.99  ? 43  GLY C C   1 
ATOM   4848 O  O   . GLY C 1 47  ? -28.73  -0.141  43.056  1   59     ? 43  GLY C O   1 
ATOM   4849 N  N   . VAL C 1 48  ? -29.52  -1.672  41.62   1   45.67  ? 44  VAL C N   1 
ATOM   4850 C  CA  . VAL C 1 48  ? -29.936 -0.687  40.64   1   43.78  ? 44  VAL C CA  1 
ATOM   4851 C  C   . VAL C 1 48  ? -31.328 -0.208  41.027  1   48.93  ? 44  VAL C C   1 
ATOM   4852 O  O   . VAL C 1 48  ? -32.237 -1.024  41.186  1   49.55  ? 44  VAL C O   1 
ATOM   4853 C  CB  . VAL C 1 48  ? -29.986 -1.309  39.229  1   41.13  ? 44  VAL C CB  1 
ATOM   4854 C  CG1 . VAL C 1 48  ? -30.366 -0.299  38.143  1   35.47  ? 44  VAL C CG1 1 
ATOM   4855 C  CG2 . VAL C 1 48  ? -28.694 -2.044  38.887  1   39.72  ? 44  VAL C CG2 1 
ATOM   4856 N  N   . PRO C 1 49  ? -31.548 1.124   41.15   1   50.34  ? 45  PRO C N   1 
ATOM   4857 C  CA  . PRO C 1 49  ? -32.838 1.666   41.595  1   46.92  ? 45  PRO C CA  1 
ATOM   4858 C  C   . PRO C 1 49  ? -33.971 1.223   40.674  1   49.13  ? 45  PRO C C   1 
ATOM   4859 O  O   . PRO C 1 49  ? -33.827 1.234   39.448  1   48.98  ? 45  PRO C O   1 
ATOM   4860 C  CB  . PRO C 1 49  ? -32.648 3.19    41.494  1   45.37  ? 45  PRO C CB  1 
ATOM   4861 C  CG  . PRO C 1 49  ? -31.153 3.378   41.525  1   46.75  ? 45  PRO C CG  1 
ATOM   4862 C  CD  . PRO C 1 49  ? -30.569 2.172   40.819  1   48.4   ? 45  PRO C CD  1 
ATOM   4863 N  N   . SER C 1 50  ? -35.121 0.901   41.272  1   48.1   ? 46  SER C N   1 
ATOM   4864 C  CA  . SER C 1 50  ? -36.286 0.539   40.486  1   48.38  ? 46  SER C CA  1 
ATOM   4865 C  C   . SER C 1 50  ? -36.695 1.674   39.542  1   47.97  ? 46  SER C C   1 
ATOM   4866 O  O   . SER C 1 50  ? -37.166 1.388   38.439  1   49.99  ? 46  SER C O   1 
ATOM   4867 C  CB  . SER C 1 50  ? -37.398 0.043   41.357  1   49.18  ? 46  SER C CB  1 
ATOM   4868 O  OG  . SER C 1 50  ? -37.722 1.043   42.308  1   58.41  ? 46  SER C OG  1 
ATOM   4869 N  N   . THR C 1 51  ? -36.486 2.953   39.921  1   47.88  ? 47  THR C N   1 
ATOM   4870 C  CA  . THR C 1 51  ? -36.834 4.066   39.02   1   48.8   ? 47  THR C CA  1 
ATOM   4871 C  C   . THR C 1 51  ? -36.008 3.999   37.744  1   45.46  ? 47  THR C C   1 
ATOM   4872 O  O   . THR C 1 51  ? -36.506 4.344   36.691  1   51.78  ? 47  THR C O   1 
ATOM   4873 C  CB  . THR C 1 51  ? -36.725 5.474   39.605  1   52.28  ? 47  THR C CB  1 
ATOM   4874 O  OG1 . THR C 1 51  ? -35.447 5.521   40.215  1   63.04  ? 47  THR C OG1 1 
ATOM   4875 C  CG2 . THR C 1 51  ? -37.71  5.756   40.721  1   63.85  ? 47  THR C CG2 1 
ATOM   4876 N  N   . ALA C 1 52  ? -34.748 3.558   37.833  1   44.27  ? 48  ALA C N   1 
ATOM   4877 C  CA  . ALA C 1 52  ? -33.893 3.491   36.664  1   41.5   ? 48  ALA C CA  1 
ATOM   4878 C  C   . ALA C 1 52  ? -34.298 2.303   35.786  1   47.77  ? 48  ALA C C   1 
ATOM   4879 O  O   . ALA C 1 52  ? -34.336 2.432   34.559  1   52.79  ? 48  ALA C O   1 
ATOM   4880 C  CB  . ALA C 1 52  ? -32.449 3.417   37.083  1   38.96  ? 48  ALA C CB  1 
ATOM   4881 N  N   . ILE C 1 53  ? -34.623 1.163   36.417  1   46.12  ? 49  ILE C N   1 
ATOM   4882 C  CA  . ILE C 1 53  ? -35.06  -0.02   35.694  1   46.05  ? 49  ILE C CA  1 
ATOM   4883 C  C   . ILE C 1 53  ? -36.304 0.276   34.852  1   45.81  ? 49  ILE C C   1 
ATOM   4884 O  O   . ILE C 1 53  ? -36.355 -0.085  33.677  1   47.22  ? 49  ILE C O   1 
ATOM   4885 C  CB  . ILE C 1 53  ? -35.25  -1.191  36.662  1   43.79  ? 49  ILE C CB  1 
ATOM   4886 C  CG1 . ILE C 1 53  ? -33.911 -1.673  37.15   1   41.06  ? 49  ILE C CG1 1 
ATOM   4887 C  CG2 . ILE C 1 53  ? -36.037 -2.324  35.996  1   44.74  ? 49  ILE C CG2 1 
ATOM   4888 C  CD1 . ILE C 1 53  ? -34.02  -2.474  38.424  1   44.51  ? 49  ILE C CD1 1 
ATOM   4889 N  N   . ARG C 1 54  ? -37.281 0.964   35.445  1   45.8   ? 50  ARG C N   1 
ATOM   4890 C  CA  . ARG C 1 54  ? -38.462 1.381   34.704  1   47.51  ? 50  ARG C CA  1 
ATOM   4891 C  C   . ARG C 1 54  ? -38.122 2.441   33.657  1   47.43  ? 50  ARG C C   1 
ATOM   4892 O  O   . ARG C 1 54  ? -38.587 2.342   32.531  1   48.1   ? 50  ARG C O   1 
ATOM   4893 C  CB  . ARG C 1 54  ? -39.536 1.91    35.661  1   48.92  ? 50  ARG C CB  1 
ATOM   4894 C  CG  . ARG C 1 54  ? -40.192 0.806   36.482  1   47.92  ? 50  ARG C CG  1 
ATOM   4895 C  CD  . ARG C 1 54  ? -41.207 1.413   37.42   1   46.7   ? 50  ARG C CD  1 
ATOM   4896 N  NE  . ARG C 1 54  ? -41.86  0.359   38.186  1   47.6   ? 50  ARG C NE  1 
ATOM   4897 C  CZ  . ARG C 1 54  ? -42.682 0.602   39.191  1   53.41  ? 50  ARG C CZ  1 
ATOM   4898 N  NH1 . ARG C 1 54  ? -42.972 1.85    39.537  1   51.14  ? 50  ARG C NH1 1 
ATOM   4899 N  NH2 . ARG C 1 54  ? -43.238 -0.418  39.825  1   52.86  ? 50  ARG C NH2 1 
ATOM   4900 N  N   . GLU C 1 55  ? -37.356 3.477   34.034  1   46.99  ? 51  GLU C N   1 
ATOM   4901 C  CA  . GLU C 1 55  ? -37.041 4.541   33.091  1   47.11  ? 51  GLU C CA  1 
ATOM   4902 C  C   . GLU C 1 55  ? -36.349 3.993   31.839  1   49.63  ? 51  GLU C C   1 
ATOM   4903 O  O   . GLU C 1 55  ? -36.764 4.29    30.718  1   50.56  ? 51  GLU C O   1 
ATOM   4904 C  CB  . GLU C 1 55  ? -36.215 5.686   33.67   1   48.41  ? 51  GLU C CB  1 
ATOM   4905 C  CG  . GLU C 1 55  ? -35.881 6.731   32.605  1   51.9   ? 51  GLU C CG  1 
ATOM   4906 C  CD  . GLU C 1 55  ? -35.42  8.091   33.096  1   57.87  ? 51  GLU C CD  1 
ATOM   4907 O  OE1 . GLU C 1 55  ? -34.941 8.136   34.244  1   55.32  ? 51  GLU C OE1 1 
ATOM   4908 O  OE2 . GLU C 1 55  ? -35.601 9.106   32.359  1   62.23  ? 51  GLU C OE2 1 
ATOM   4909 N  N   . ILE C 1 56  ? -35.275 3.222   32.029  1   48.28  ? 52  ILE C N   1 
ATOM   4910 C  CA  . ILE C 1 56  ? -34.516 2.681   30.915  1   46.23  ? 52  ILE C CA  1 
ATOM   4911 C  C   . ILE C 1 56  ? -35.391 1.718   30.109  1   50.68  ? 52  ILE C C   1 
ATOM   4912 O  O   . ILE C 1 56  ? -35.512 1.886   28.898  1   54.01  ? 52  ILE C O   1 
ATOM   4913 C  CB  . ILE C 1 56  ? -33.209 2.016   31.398  1   46.28  ? 52  ILE C CB  1 
ATOM   4914 C  CG1 . ILE C 1 56  ? -32.286 3.024   32.112  1   48.92  ? 52  ILE C CG1 1 
ATOM   4915 C  CG2 . ILE C 1 56  ? -32.485 1.307   30.247  1   44.05  ? 52  ILE C CG2 1 
ATOM   4916 C  CD1 . ILE C 1 56  ? -31.285 2.416   33.092  1   43.26  ? 52  ILE C CD1 1 
ATOM   4917 N  N   . SER C 1 57  ? -35.985 0.707   30.762  1   52.4   ? 53  SER C N   1 
ATOM   4918 C  CA  . SER C 1 57  ? -36.708 -0.345  30.049  1   58.8   ? 53  SER C CA  1 
ATOM   4919 C  C   . SER C 1 57  ? -37.857 0.219   29.205  1   60.33  ? 53  SER C C   1 
ATOM   4920 O  O   . SER C 1 57  ? -38.026 -0.179  28.059  1   63.24  ? 53  SER C O   1 
ATOM   4921 C  CB  . SER C 1 57  ? -37.177 -1.463  30.971  1   58.66  ? 53  SER C CB  1 
ATOM   4922 O  OG  . SER C 1 57  ? -38.051 -0.99   31.989  1   60.98  ? 53  SER C OG  1 
ATOM   4923 N  N   . LEU C 1 58  ? -38.604 1.181   29.756  1   55.35  ? 54  LEU C N   1 
ATOM   4924 C  CA  . LEU C 1 58  ? -39.774 1.747   29.097  1   57.11  ? 54  LEU C CA  1 
ATOM   4925 C  C   . LEU C 1 58  ? -39.39  2.663   27.933  1   55.34  ? 54  LEU C C   1 
ATOM   4926 O  O   . LEU C 1 58  ? -40.111 2.679   26.942  1   62.73  ? 54  LEU C O   1 
ATOM   4927 C  CB  . LEU C 1 58  ? -40.762 2.414   30.065  1   54.01  ? 54  LEU C CB  1 
ATOM   4928 C  CG  . LEU C 1 58  ? -41.289 1.506   31.19   1   56.1   ? 54  LEU C CG  1 
ATOM   4929 C  CD1 . LEU C 1 58  ? -42.174 2.2     32.204  1   50.46  ? 54  LEU C CD1 1 
ATOM   4930 C  CD2 . LEU C 1 58  ? -42.002 0.29    30.639  1   56.4   ? 54  LEU C CD2 1 
ATOM   4931 N  N   . LEU C 1 59  ? -38.29  3.428   28.057  1   50.69  ? 55  LEU C N   1 
ATOM   4932 C  CA  . LEU C 1 59  ? -37.798 4.314   27      1   50.15  ? 55  LEU C CA  1 
ATOM   4933 C  C   . LEU C 1 59  ? -37.165 3.531   25.846  1   54.03  ? 55  LEU C C   1 
ATOM   4934 O  O   . LEU C 1 59  ? -37.154 3.998   24.705  1   59.33  ? 55  LEU C O   1 
ATOM   4935 C  CB  . LEU C 1 59  ? -36.778 5.317   27.542  1   47.21  ? 55  LEU C CB  1 
ATOM   4936 C  CG  . LEU C 1 59  ? -37.32  6.53    28.299  1   47.77  ? 55  LEU C CG  1 
ATOM   4937 C  CD1 . LEU C 1 59  ? -36.156 7.359   28.75   1   49.01  ? 55  LEU C CD1 1 
ATOM   4938 C  CD2 . LEU C 1 59  ? -38.24  7.381   27.445  1   48.66  ? 55  LEU C CD2 1 
ATOM   4939 N  N   . LYS C 1 60  ? -36.556 2.381   26.155  1   58.57  ? 56  LYS C N   1 
ATOM   4940 C  CA  . LYS C 1 60  ? -36.002 1.535   25.114  1   66.2   ? 56  LYS C CA  1 
ATOM   4941 C  C   . LYS C 1 60  ? -37.097 1.193   24.099  1   69.78  ? 56  LYS C C   1 
ATOM   4942 O  O   . LYS C 1 60  ? -36.812 1.061   22.916  1   73.23  ? 56  LYS C O   1 
ATOM   4943 C  CB  . LYS C 1 60  ? -35.23  0.349   25.708  1   68.21  ? 56  LYS C CB  1 
ATOM   4944 C  CG  . LYS C 1 60  ? -33.815 0.745   26.131  1   70.46  ? 56  LYS C CG  1 
ATOM   4945 C  CD  . LYS C 1 60  ? -32.746 -0.324  26.359  1   70.1   ? 56  LYS C CD  1 
ATOM   4946 C  CE  . LYS C 1 60  ? -32.392 -1.174  25.168  1   72.17  ? 56  LYS C CE  1 
ATOM   4947 N  NZ  . LYS C 1 60  ? -32.981 -2.521  25.188  1   74.65  ? 56  LYS C NZ  1 
ATOM   4948 N  N   . GLU C 1 61  ? -38.349 1.085   24.56   1   65.81  ? 57  GLU C N   1 
ATOM   4949 C  CA  . GLU C 1 61  ? -39.465 0.698   23.716  1   62.09  ? 57  GLU C CA  1 
ATOM   4950 C  C   . GLU C 1 61  ? -40.189 1.898   23.104  1   66.13  ? 57  GLU C C   1 
ATOM   4951 O  O   . GLU C 1 61  ? -40.876 1.733   22.101  1   79.37  ? 57  GLU C O   1 
ATOM   4952 C  CB  . GLU C 1 61  ? -40.467 -0.07   24.571  1   71.35  ? 57  GLU C CB  1 
ATOM   4953 C  CG  . GLU C 1 61  ? -40.057 -1.521  24.79   1   76.27  ? 57  GLU C CG  1 
ATOM   4954 C  CD  . GLU C 1 61  ? -41.139 -2.337  25.466  1   79.97  ? 57  GLU C CD  1 
ATOM   4955 O  OE1 . GLU C 1 61  ? -40.86  -3.508  25.848  1   98.62  ? 57  GLU C OE1 1 
ATOM   4956 O  OE2 . GLU C 1 61  ? -42.27  -1.798  25.569  1   71     ? 57  GLU C OE2 1 
ATOM   4957 N  N   . LEU C 1 62  ? -40.066 3.092   23.697  1   60.75  ? 58  LEU C N   1 
ATOM   4958 C  CA  . LEU C 1 62  ? -40.852 4.235   23.258  1   57.17  ? 58  LEU C CA  1 
ATOM   4959 C  C   . LEU C 1 62  ? -40.043 5.133   22.322  1   55.87  ? 58  LEU C C   1 
ATOM   4960 O  O   . LEU C 1 62  ? -39.486 6.123   22.78   1   63.24  ? 58  LEU C O   1 
ATOM   4961 C  CB  . LEU C 1 62  ? -41.332 5.034   24.472  1   56.62  ? 58  LEU C CB  1 
ATOM   4962 C  CG  . LEU C 1 62  ? -42.27  4.326   25.45   1   60.09  ? 58  LEU C CG  1 
ATOM   4963 C  CD1 . LEU C 1 62  ? -42.436 5.158   26.698  1   60.14  ? 58  LEU C CD1 1 
ATOM   4964 C  CD2 . LEU C 1 62  ? -43.62  4.075   24.844  1   60.38  ? 58  LEU C CD2 1 
ATOM   4965 N  N   . ASN C 1 63  ? -40.037 4.832   21.013  1   60.38  ? 59  ASN C N   1 
ATOM   4966 C  CA  . ASN C 1 63  ? -39.387 5.656   20.001  1   61.04  ? 59  ASN C CA  1 
ATOM   4967 C  C   . ASN C 1 63  ? -40.433 6.462   19.238  1   59.48  ? 59  ASN C C   1 
ATOM   4968 O  O   . ASN C 1 63  ? -41.182 5.911   18.436  1   64.62  ? 59  ASN C O   1 
ATOM   4969 C  CB  . ASN C 1 63  ? -38.413 4.854   19.139  1   72.92  ? 59  ASN C CB  1 
ATOM   4970 C  CG  . ASN C 1 63  ? -37.196 4.416   19.937  1   98.7   ? 59  ASN C CG  1 
ATOM   4971 O  OD1 . ASN C 1 63  ? -37.006 3.228   20.233  1   110.78 ? 59  ASN C OD1 1 
ATOM   4972 N  ND2 . ASN C 1 63  ? -36.358 5.359   20.34   1   100.53 ? 59  ASN C ND2 1 
ATOM   4973 N  N   . HIS C 1 64  ? -40.482 7.77    19.524  1   55.63  ? 60  HIS C N   1 
ATOM   4974 C  CA  . HIS C 1 64  ? -41.453 8.698   18.955  1   54.91  ? 60  HIS C CA  1 
ATOM   4975 C  C   . HIS C 1 64  ? -40.857 10.105  18.901  1   55.29  ? 60  HIS C C   1 
ATOM   4976 O  O   . HIS C 1 64  ? -40.015 10.474  19.719  1   59.63  ? 60  HIS C O   1 
ATOM   4977 C  CB  . HIS C 1 64  ? -42.743 8.705   19.774  1   54.64  ? 60  HIS C CB  1 
ATOM   4978 C  CG  . HIS C 1 64  ? -43.82  9.509   19.138  1   61.21  ? 60  HIS C CG  1 
ATOM   4979 N  ND1 . HIS C 1 64  ? -43.939 10.877  19.314  1   61.44  ? 60  HIS C ND1 1 
ATOM   4980 C  CD2 . HIS C 1 64  ? -44.819 9.142   18.325  1   58.09  ? 60  HIS C CD2 1 
ATOM   4981 C  CE1 . HIS C 1 64  ? -44.973 11.318  18.606  1   60.86  ? 60  HIS C CE1 1 
ATOM   4982 N  NE2 . HIS C 1 64  ? -45.534 10.285  18.015  1   60.55  ? 60  HIS C NE2 1 
ATOM   4983 N  N   . PRO C 1 65  ? -41.218 10.934  17.903  1   56.43  ? 61  PRO C N   1 
ATOM   4984 C  CA  . PRO C 1 65  ? -40.646 12.277  17.805  1   57.35  ? 61  PRO C CA  1 
ATOM   4985 C  C   . PRO C 1 65  ? -40.947 13.201  18.98   1   57.62  ? 61  PRO C C   1 
ATOM   4986 O  O   . PRO C 1 65  ? -40.204 14.163  19.155  1   62.7   ? 61  PRO C O   1 
ATOM   4987 C  CB  . PRO C 1 65  ? -41.088 12.868  16.465  1   53.94  ? 61  PRO C CB  1 
ATOM   4988 C  CG  . PRO C 1 65  ? -42.187 11.935  16.009  1   57.72  ? 61  PRO C CG  1 
ATOM   4989 C  CD  . PRO C 1 65  ? -42.102 10.61   16.779  1   54.96  ? 61  PRO C CD  1 
ATOM   4990 N  N   . ASN C 1 66  ? -41.983 12.877  19.784  1   53.65  ? 62  ASN C N   1 
ATOM   4991 C  CA  . ASN C 1 66  ? -42.426 13.712  20.904  1   53.08  ? 62  ASN C CA  1 
ATOM   4992 C  C   . ASN C 1 66  ? -42.153 13.049  22.262  1   56.77  ? 62  ASN C C   1 
ATOM   4993 O  O   . ASN C 1 66  ? -42.787 13.39   23.27   1   56.06  ? 62  ASN C O   1 
ATOM   4994 C  CB  . ASN C 1 66  ? -43.896 14.098  20.768  1   47.71  ? 62  ASN C CB  1 
ATOM   4995 C  CG  . ASN C 1 66  ? -44.145 14.894  19.51   1   53.55  ? 62  ASN C CG  1 
ATOM   4996 O  OD1 . ASN C 1 66  ? -44.858 14.432  18.617  1   65.92  ? 62  ASN C OD1 1 
ATOM   4997 N  ND2 . ASN C 1 66  ? -43.577 16.087  19.405  1   49.57  ? 62  ASN C ND2 1 
ATOM   4998 N  N   . ILE C 1 67  ? -41.212 12.092  22.279  1   52.94  ? 63  ILE C N   1 
ATOM   4999 C  CA  . ILE C 1 67  ? -40.72  11.48   23.503  1   50.12  ? 63  ILE C CA  1 
ATOM   5000 C  C   . ILE C 1 67  ? -39.196 11.558  23.457  1   50.2   ? 63  ILE C C   1 
ATOM   5001 O  O   . ILE C 1 67  ? -38.597 11.159  22.454  1   48.17  ? 63  ILE C O   1 
ATOM   5002 C  CB  . ILE C 1 67  ? -41.213 10.022  23.633  1   44.87  ? 63  ILE C CB  1 
ATOM   5003 C  CG1 . ILE C 1 67  ? -42.736 9.913   23.621  1   43.59  ? 63  ILE C CG1 1 
ATOM   5004 C  CG2 . ILE C 1 67  ? -40.622 9.366   24.875  1   41.63  ? 63  ILE C CG2 1 
ATOM   5005 C  CD1 . ILE C 1 67  ? -43.231 8.475   23.66   1   43.24  ? 63  ILE C CD1 1 
ATOM   5006 N  N   . VAL C 1 68  ? -38.585 12.051  24.546  1   47.15  ? 64  VAL C N   1 
ATOM   5007 C  CA  . VAL C 1 68  ? -37.145 12.255  24.604  1   45.25  ? 64  VAL C CA  1 
ATOM   5008 C  C   . VAL C 1 68  ? -36.453 10.929  24.265  1   48.57  ? 64  VAL C C   1 
ATOM   5009 O  O   . VAL C 1 68  ? -36.883 9.848   24.682  1   43.88  ? 64  VAL C O   1 
ATOM   5010 C  CB  . VAL C 1 68  ? -36.698 12.793  25.979  1   42.97  ? 64  VAL C CB  1 
ATOM   5011 C  CG1 . VAL C 1 68  ? -36.912 11.764  27.097  1   38.59  ? 64  VAL C CG1 1 
ATOM   5012 C  CG2 . VAL C 1 68  ? -35.243 13.253  25.972  1   42.12  ? 64  VAL C CG2 1 
ATOM   5013 N  N   . LYS C 1 69  ? -35.349 11.039  23.522  1   47.63  ? 65  LYS C N   1 
ATOM   5014 C  CA  . LYS C 1 69  ? -34.644 9.88    23.027  1   49.6   ? 65  LYS C CA  1 
ATOM   5015 C  C   . LYS C 1 69  ? -33.539 9.484   24.007  1   48.81  ? 65  LYS C C   1 
ATOM   5016 O  O   . LYS C 1 69  ? -32.615 10.257  24.283  1   49.77  ? 65  LYS C O   1 
ATOM   5017 C  CB  . LYS C 1 69  ? -34.229 10.142  21.573  1   50.73  ? 65  LYS C CB  1 
ATOM   5018 C  CG  . LYS C 1 69  ? -33.3   9.111   20.98   1   66.63  ? 65  LYS C CG  1 
ATOM   5019 C  CD  . LYS C 1 69  ? -33.932 7.754   20.691  1   83.89  ? 65  LYS C CD  1 
ATOM   5020 C  CE  . LYS C 1 69  ? -32.958 6.824   20.012  1   85.19  ? 65  LYS C CE  1 
ATOM   5021 N  NZ  . LYS C 1 69  ? -33.618 5.883   19.111  1   86.57  ? 65  LYS C NZ  1 
ATOM   5022 N  N   . LEU C 1 70  ? -33.639 8.248   24.507  1   48.05  ? 66  LEU C N   1 
ATOM   5023 C  CA  . LEU C 1 70  ? -32.526 7.603   25.187  1   48.57  ? 66  LEU C CA  1 
ATOM   5024 C  C   . LEU C 1 70  ? -31.607 7.04    24.11   1   51.83  ? 66  LEU C C   1 
ATOM   5025 O  O   . LEU C 1 70  ? -32.042 6.218   23.319  1   57.06  ? 66  LEU C O   1 
ATOM   5026 C  CB  . LEU C 1 70  ? -33.057 6.5     26.095  1   44.7   ? 66  LEU C CB  1 
ATOM   5027 C  CG  . LEU C 1 70  ? -32.036 5.821   27.007  1   46.05  ? 66  LEU C CG  1 
ATOM   5028 C  CD1 . LEU C 1 70  ? -31.334 6.805   27.93   1   43.55  ? 66  LEU C CD1 1 
ATOM   5029 C  CD2 . LEU C 1 70  ? -32.709 4.735   27.832  1   46.06  ? 66  LEU C CD2 1 
ATOM   5030 N  N   . LEU C 1 71  ? -30.365 7.532   24.056  1   51.71  ? 67  LEU C N   1 
ATOM   5031 C  CA  . LEU C 1 71  ? -29.414 7.196   22.999  1   49.67  ? 67  LEU C CA  1 
ATOM   5032 C  C   . LEU C 1 71  ? -28.567 5.982   23.377  1   48.61  ? 67  LEU C C   1 
ATOM   5033 O  O   . LEU C 1 71  ? -28.194 5.198   22.509  1   50.58  ? 67  LEU C O   1 
ATOM   5034 C  CB  . LEU C 1 71  ? -28.523 8.402   22.699  1   46.32  ? 67  LEU C CB  1 
ATOM   5035 C  CG  . LEU C 1 71  ? -29.261 9.679   22.29   1   45.14  ? 67  LEU C CG  1 
ATOM   5036 C  CD1 . LEU C 1 71  ? -28.328 10.881  22.366  1   44.22  ? 67  LEU C CD1 1 
ATOM   5037 C  CD2 . LEU C 1 71  ? -29.787 9.517   20.893  1   43.4   ? 67  LEU C CD2 1 
ATOM   5038 N  N   . ASP C 1 72  ? -28.222 5.87    24.667  1   46.56  ? 68  ASP C N   1 
ATOM   5039 C  CA  . ASP C 1 72  ? -27.282 4.868   25.126  1   45.99  ? 68  ASP C CA  1 
ATOM   5040 C  C   . ASP C 1 72  ? -27.358 4.741   26.647  1   49.8   ? 68  ASP C C   1 
ATOM   5041 O  O   . ASP C 1 72  ? -27.849 5.639   27.345  1   46.23  ? 68  ASP C O   1 
ATOM   5042 C  CB  . ASP C 1 72  ? -25.872 5.176   24.646  1   48.65  ? 68  ASP C CB  1 
ATOM   5043 C  CG  . ASP C 1 72  ? -24.923 3.985   24.554  1   53.21  ? 68  ASP C CG  1 
ATOM   5044 O  OD1 . ASP C 1 72  ? -25.307 2.864   24.949  1   57.32  ? 68  ASP C OD1 1 
ATOM   5045 O  OD2 . ASP C 1 72  ? -23.793 4.175   24.073  1   61.6   ? 68  ASP C OD2 1 
ATOM   5046 N  N   . VAL C 1 73  ? -26.884 3.579   27.12   1   49.37  ? 69  VAL C N   1 
ATOM   5047 C  CA  . VAL C 1 73  ? -26.707 3.257   28.521  1   51.35  ? 69  VAL C CA  1 
ATOM   5048 C  C   . VAL C 1 73  ? -25.299 2.704   28.673  1   54.85  ? 69  VAL C C   1 
ATOM   5049 O  O   . VAL C 1 73  ? -24.996 1.634   28.138  1   56.78  ? 69  VAL C O   1 
ATOM   5050 C  CB  . VAL C 1 73  ? -27.739 2.256   29.062  1   48.87  ? 69  VAL C CB  1 
ATOM   5051 C  CG1 . VAL C 1 73  ? -27.616 2.142   30.577  1   51.35  ? 69  VAL C CG1 1 
ATOM   5052 C  CG2 . VAL C 1 73  ? -29.15  2.664   28.669  1   49.2   ? 69  VAL C CG2 1 
ATOM   5053 N  N   . ILE C 1 74  ? -24.449 3.492   29.346  1   55.49  ? 70  ILE C N   1 
ATOM   5054 C  CA  . ILE C 1 74  ? -23.068 3.111   29.592  1   59.67  ? 70  ILE C CA  1 
ATOM   5055 C  C   . ILE C 1 74  ? -22.95  2.64    31.036  1   58.34  ? 70  ILE C C   1 
ATOM   5056 O  O   . ILE C 1 74  ? -23.155 3.424   31.944  1   55.59  ? 70  ILE C O   1 
ATOM   5057 C  CB  . ILE C 1 74  ? -22.105 4.264   29.251  1   59.21  ? 70  ILE C CB  1 
ATOM   5058 C  CG1 . ILE C 1 74  ? -22.12  4.519   27.759  1   61.82  ? 70  ILE C CG1 1 
ATOM   5059 C  CG2 . ILE C 1 74  ? -20.692 3.955   29.735  1   55.92  ? 70  ILE C CG2 1 
ATOM   5060 C  CD1 . ILE C 1 74  ? -21.787 5.935   27.361  1   67.07  ? 70  ILE C CD1 1 
ATOM   5061 N  N   . HIS C 1 75  ? -22.611 1.356   31.201  1   62.92  ? 71  HIS C N   1 
ATOM   5062 C  CA  . HIS C 1 75  ? -22.489 0.672   32.484  1   67.06  ? 71  HIS C CA  1 
ATOM   5063 C  C   . HIS C 1 75  ? -21.043 0.71    32.976  1   67.06  ? 71  HIS C C   1 
ATOM   5064 O  O   . HIS C 1 75  ? -20.109 0.705   32.192  1   67.08  ? 71  HIS C O   1 
ATOM   5065 C  CB  . HIS C 1 75  ? -22.839 -0.826  32.382  1   69.37  ? 71  HIS C CB  1 
ATOM   5066 C  CG  . HIS C 1 75  ? -24.151 -1.171  31.75   1   67.13  ? 71  HIS C CG  1 
ATOM   5067 N  ND1 . HIS C 1 75  ? -25.079 -1.941  32.414  1   64.01  ? 71  HIS C ND1 1 
ATOM   5068 C  CD2 . HIS C 1 75  ? -24.707 -0.849  30.549  1   68.25  ? 71  HIS C CD2 1 
ATOM   5069 C  CE1 . HIS C 1 75  ? -26.151 -2.076  31.635  1   74.75  ? 71  HIS C CE1 1 
ATOM   5070 N  NE2 . HIS C 1 75  ? -25.953 -1.425  30.488  1   68.91  ? 71  HIS C NE2 1 
ATOM   5071 N  N   . THR C 1 76  ? -20.87  0.772   34.298  1   70.68  ? 72  THR C N   1 
ATOM   5072 C  CA  . THR C 1 76  ? -19.612 0.509   34.989  1   69.64  ? 72  THR C CA  1 
ATOM   5073 C  C   . THR C 1 76  ? -20.027 -0.377  36.144  1   68.22  ? 72  THR C C   1 
ATOM   5074 O  O   . THR C 1 76  ? -21.216 -0.675  36.248  1   65.71  ? 72  THR C O   1 
ATOM   5075 C  CB  . THR C 1 76  ? -18.875 1.765   35.487  1   70.44  ? 72  THR C CB  1 
ATOM   5076 O  OG1 . THR C 1 76  ? -19.533 2.342   36.612  1   78.91  ? 72  THR C OG1 1 
ATOM   5077 C  CG2 . THR C 1 76  ? -18.71  2.856   34.442  1   66.42  ? 72  THR C CG2 1 
ATOM   5078 N  N   . GLU C 1 77  ? -19.077 -0.726  37.016  1   76.16  ? 73  GLU C N   1 
ATOM   5079 C  CA  . GLU C 1 77  ? -19.422 -1.558  38.153  1   79.06  ? 73  GLU C CA  1 
ATOM   5080 C  C   . GLU C 1 77  ? -20.098 -0.672  39.198  1   76.06  ? 73  GLU C C   1 
ATOM   5081 O  O   . GLU C 1 77  ? -20.912 -1.147  39.982  1   79.57  ? 73  GLU C O   1 
ATOM   5082 C  CB  . GLU C 1 77  ? -18.215 -2.412  38.563  1   88.22  ? 73  GLU C CB  1 
ATOM   5083 C  CG  . GLU C 1 77  ? -18.474 -3.39   39.712  1   111.29 ? 73  GLU C CG  1 
ATOM   5084 C  CD  . GLU C 1 77  ? -17.343 -4.318  40.16   1   131.89 ? 73  GLU C CD  1 
ATOM   5085 O  OE1 . GLU C 1 77  ? -16.263 -4.167  39.56   1   137.57 ? 73  GLU C OE1 1 
ATOM   5086 O  OE2 . GLU C 1 77  ? -17.49  -5.17   41.077  1   142.4  ? 73  GLU C OE2 1 
ATOM   5087 N  N   . ASN C 1 78  ? -19.775 0.628   39.165  1   77.47  ? 74  ASN C N   1 
ATOM   5088 C  CA  . ASN C 1 78  ? -20.13  1.561   40.22   1   71.9   ? 74  ASN C CA  1 
ATOM   5089 C  C   . ASN C 1 78  ? -21.202 2.54    39.77   1   69.91  ? 74  ASN C C   1 
ATOM   5090 O  O   . ASN C 1 78  ? -22.013 2.982   40.578  1   67.31  ? 74  ASN C O   1 
ATOM   5091 C  CB  . ASN C 1 78  ? -18.883 2.145   40.864  1   73.93  ? 74  ASN C CB  1 
ATOM   5092 C  CG  . ASN C 1 78  ? -18.255 1.125   41.795  1   84.85  ? 74  ASN C CG  1 
ATOM   5093 O  OD1 . ASN C 1 78  ? -17.236 0.514   41.45   1   84.83  ? 74  ASN C OD1 1 
ATOM   5094 N  ND2 . ASN C 1 78  ? -18.867 0.872   42.949  1   82.72  ? 74  ASN C ND2 1 
ATOM   5095 N  N   . LYS C 1 79  ? -21.211 2.873   38.476  1   72.96  ? 75  LYS C N   1 
ATOM   5096 C  CA  . LYS C 1 79  ? -22.133 3.897   38.007  1   69.72  ? 75  LYS C CA  1 
ATOM   5097 C  C   . LYS C 1 79  ? -22.86  3.458   36.749  1   65.02  ? 75  LYS C C   1 
ATOM   5098 O  O   . LYS C 1 79  ? -22.36  2.647   35.978  1   74.13  ? 75  LYS C O   1 
ATOM   5099 C  CB  . LYS C 1 79  ? -21.388 5.2     37.72   1   75.31  ? 75  LYS C CB  1 
ATOM   5100 C  CG  . LYS C 1 79  ? -21.463 6.231   38.833  1   87.52  ? 75  LYS C CG  1 
ATOM   5101 C  CD  . LYS C 1 79  ? -20.289 7.206   38.816  1   101.22 ? 75  LYS C CD  1 
ATOM   5102 C  CE  . LYS C 1 79  ? -18.985 6.548   39.2    1   105.46 ? 75  LYS C CE  1 
ATOM   5103 N  NZ  . LYS C 1 79  ? -17.813 7.185   38.586  1   98.1   ? 75  LYS C NZ  1 
ATOM   5104 N  N   . LEU C 1 80  ? -24.033 4.05    36.549  1   60.47  ? 76  LEU C N   1 
ATOM   5105 C  CA  . LEU C 1 80  ? -24.809 3.906   35.327  1   56.06  ? 76  LEU C CA  1 
ATOM   5106 C  C   . LEU C 1 80  ? -24.976 5.293   34.703  1   55.58  ? 76  LEU C C   1 
ATOM   5107 O  O   . LEU C 1 80  ? -25.444 6.214   35.38   1   53.98  ? 76  LEU C O   1 
ATOM   5108 C  CB  . LEU C 1 80  ? -26.149 3.333   35.787  1   55.2   ? 76  LEU C CB  1 
ATOM   5109 C  CG  . LEU C 1 80  ? -26.914 2.436   34.814  1   53.85  ? 76  LEU C CG  1 
ATOM   5110 C  CD1 . LEU C 1 80  ? -26.006 1.308   34.351  1   60.54  ? 76  LEU C CD1 1 
ATOM   5111 C  CD2 . LEU C 1 80  ? -28.097 1.824   35.537  1   51.35  ? 76  LEU C CD2 1 
ATOM   5112 N  N   . TYR C 1 81  ? -24.553 5.468   33.441  1   51.01  ? 77  TYR C N   1 
ATOM   5113 C  CA  . TYR C 1 81  ? -24.729 6.742   32.75   1   53.68  ? 77  TYR C CA  1 
ATOM   5114 C  C   . TYR C 1 81  ? -25.769 6.606   31.639  1   53.82  ? 77  TYR C C   1 
ATOM   5115 O  O   . TYR C 1 81  ? -25.56  5.836   30.711  1   57.8   ? 77  TYR C O   1 
ATOM   5116 C  CB  . TYR C 1 81  ? -23.422 7.215   32.115  1   55.55  ? 77  TYR C CB  1 
ATOM   5117 C  CG  . TYR C 1 81  ? -22.332 7.677   33.069  1   60.33  ? 77  TYR C CG  1 
ATOM   5118 C  CD1 . TYR C 1 81  ? -22.276 8.996   33.494  1   63.02  ? 77  TYR C CD1 1 
ATOM   5119 C  CD2 . TYR C 1 81  ? -21.334 6.815   33.511  1   62.25  ? 77  TYR C CD2 1 
ATOM   5120 C  CE1 . TYR C 1 81  ? -21.276 9.436   34.346  1   68.26  ? 77  TYR C CE1 1 
ATOM   5121 C  CE2 . TYR C 1 81  ? -20.321 7.244   34.356  1   70.68  ? 77  TYR C CE2 1 
ATOM   5122 C  CZ  . TYR C 1 81  ? -20.291 8.561   34.793  1   76.19  ? 77  TYR C CZ  1 
ATOM   5123 O  OH  . TYR C 1 81  ? -19.261 8.971   35.62   1   80.46  ? 77  TYR C OH  1 
ATOM   5124 N  N   . LEU C 1 82  ? -26.888 7.339   31.736  1   51.79  ? 78  LEU C N   1 
ATOM   5125 C  CA  . LEU C 1 82  ? -27.865 7.374   30.66   1   50.75  ? 78  LEU C CA  1 
ATOM   5126 C  C   . LEU C 1 82  ? -27.503 8.53    29.724  1   51.27  ? 78  LEU C C   1 
ATOM   5127 O  O   . LEU C 1 82  ? -27.294 9.652   30.179  1   47.04  ? 78  LEU C O   1 
ATOM   5128 C  CB  . LEU C 1 82  ? -29.313 7.519   31.143  1   53.72  ? 78  LEU C CB  1 
ATOM   5129 C  CG  . LEU C 1 82  ? -29.795 6.741   32.373  1   54.68  ? 78  LEU C CG  1 
ATOM   5130 C  CD1 . LEU C 1 82  ? -31.278 6.492   32.263  1   49.44  ? 78  LEU C CD1 1 
ATOM   5131 C  CD2 . LEU C 1 82  ? -29.064 5.458   32.614  1   60     ? 78  LEU C CD2 1 
ATOM   5132 N  N   . VAL C 1 83  ? -27.426 8.236   28.42   1   49.62  ? 79  VAL C N   1 
ATOM   5133 C  CA  . VAL C 1 83  ? -27.093 9.233   27.422  1   46.57  ? 79  VAL C CA  1 
ATOM   5134 C  C   . VAL C 1 83  ? -28.371 9.609   26.692  1   47.19  ? 79  VAL C C   1 
ATOM   5135 O  O   . VAL C 1 83  ? -28.917 8.802   25.942  1   49.11  ? 79  VAL C O   1 
ATOM   5136 C  CB  . VAL C 1 83  ? -26.052 8.737   26.404  1   47.16  ? 79  VAL C CB  1 
ATOM   5137 C  CG1 . VAL C 1 83  ? -25.631 9.864   25.47   1   46.72  ? 79  VAL C CG1 1 
ATOM   5138 C  CG2 . VAL C 1 83  ? -24.828 8.138   27.078  1   49.8   ? 79  VAL C CG2 1 
ATOM   5139 N  N   . PHE C 1 84  ? -28.832 10.843  26.926  1   44.84  ? 80  PHE C N   1 
ATOM   5140 C  CA  . PHE C 1 84  ? -30.053 11.359  26.328  1   44.17  ? 80  PHE C CA  1 
ATOM   5141 C  C   . PHE C 1 84  ? -29.719 12.399  25.273  1   43.15  ? 80  PHE C C   1 
ATOM   5142 O  O   . PHE C 1 84  ? -28.67  13.033  25.338  1   46.7   ? 80  PHE C O   1 
ATOM   5143 C  CB  . PHE C 1 84  ? -30.89  12.079  27.389  1   41.22  ? 80  PHE C CB  1 
ATOM   5144 C  CG  . PHE C 1 84  ? -31.631 11.163  28.349  1   44.34  ? 80  PHE C CG  1 
ATOM   5145 C  CD1 . PHE C 1 84  ? -32.896 10.684  28.013  1   46.38  ? 80  PHE C CD1 1 
ATOM   5146 C  CD2 . PHE C 1 84  ? -31.08  10.814  29.583  1   42.96  ? 80  PHE C CD2 1 
ATOM   5147 C  CE1 . PHE C 1 84  ? -33.603 9.875   28.876  1   46.2   ? 80  PHE C CE1 1 
ATOM   5148 C  CE2 . PHE C 1 84  ? -31.802 10.014  30.453  1   44.71  ? 80  PHE C CE2 1 
ATOM   5149 C  CZ  . PHE C 1 84  ? -33.052 9.544   30.094  1   46.91  ? 80  PHE C CZ  1 
ATOM   5150 N  N   . GLU C 1 85  ? -30.645 12.588  24.332  1   43.25  ? 81  GLU C N   1 
ATOM   5151 C  CA  . GLU C 1 85  ? -30.581 13.722  23.425  1   46.42  ? 81  GLU C CA  1 
ATOM   5152 C  C   . GLU C 1 85  ? -30.732 15.015  24.248  1   49.86  ? 81  GLU C C   1 
ATOM   5153 O  O   . GLU C 1 85  ? -31.451 15.048  25.248  1   50.15  ? 81  GLU C O   1 
ATOM   5154 C  CB  . GLU C 1 85  ? -31.644 13.549  22.34   1   42.96  ? 81  GLU C CB  1 
ATOM   5155 C  CG  . GLU C 1 85  ? -32.93  14.267  22.694  1   47.55  ? 81  GLU C CG  1 
ATOM   5156 C  CD  . GLU C 1 85  ? -34.1   14.13   21.748  1   52.73  ? 81  GLU C CD  1 
ATOM   5157 O  OE1 . GLU C 1 85  ? -34.127 14.856  20.734  1   55.59  ? 81  GLU C OE1 1 
ATOM   5158 O  OE2 . GLU C 1 85  ? -34.984 13.295  22.044  1   51.13  ? 81  GLU C OE2 1 
ATOM   5159 N  N   . PHE C 1 86  ? -30.021 16.076  23.845  1   48.67  ? 82  PHE C N   1 
ATOM   5160 C  CA  . PHE C 1 86  ? -30.05  17.351  24.547  1   51.48  ? 82  PHE C CA  1 
ATOM   5161 C  C   . PHE C 1 86  ? -31.085 18.254  23.888  1   53.75  ? 82  PHE C C   1 
ATOM   5162 O  O   . PHE C 1 86  ? -31.057 18.423  22.676  1   57.2   ? 82  PHE C O   1 
ATOM   5163 C  CB  . PHE C 1 86  ? -28.702 18.067  24.451  1   52.57  ? 82  PHE C CB  1 
ATOM   5164 C  CG  . PHE C 1 86  ? -28.726 19.469  25.032  1   54.1   ? 82  PHE C CG  1 
ATOM   5165 C  CD1 . PHE C 1 86  ? -28.527 19.681  26.402  1   55.04  ? 82  PHE C CD1 1 
ATOM   5166 C  CD2 . PHE C 1 86  ? -28.954 20.575  24.211  1   57.12  ? 82  PHE C CD2 1 
ATOM   5167 C  CE1 . PHE C 1 86  ? -28.55  20.966  26.941  1   55.4   ? 82  PHE C CE1 1 
ATOM   5168 C  CE2 . PHE C 1 86  ? -28.98  21.868  24.743  1   58.31  ? 82  PHE C CE2 1 
ATOM   5169 C  CZ  . PHE C 1 86  ? -28.771 22.06   26.106  1   60.26  ? 82  PHE C CZ  1 
ATOM   5170 N  N   . LEU C 1 87  ? -32.005 18.806  24.682  1   54.59  ? 83  LEU C N   1 
ATOM   5171 C  CA  . LEU C 1 87  ? -32.91  19.834  24.194  1   57.19  ? 83  LEU C CA  1 
ATOM   5172 C  C   . LEU C 1 87  ? -32.668 21.136  24.961  1   60.38  ? 83  LEU C C   1 
ATOM   5173 O  O   . LEU C 1 87  ? -32.178 21.136  26.088  1   58.67  ? 83  LEU C O   1 
ATOM   5174 C  CB  . LEU C 1 87  ? -34.353 19.35   24.28   1   56.67  ? 83  LEU C CB  1 
ATOM   5175 C  CG  . LEU C 1 87  ? -34.767 18.336  23.207  1   60.08  ? 83  LEU C CG  1 
ATOM   5176 C  CD1 . LEU C 1 87  ? -34.705 16.935  23.751  1   60.04  ? 83  LEU C CD1 1 
ATOM   5177 C  CD2 . LEU C 1 87  ? -36.147 18.628  22.647  1   60.85  ? 83  LEU C CD2 1 
ATOM   5178 N  N   . HIS C 1 88  ? -32.995 22.25   24.312  1   67.77  ? 84  HIS C N   1 
ATOM   5179 C  CA  . HIS C 1 88  ? -32.575 23.578  24.73   1   73.94  ? 84  HIS C CA  1 
ATOM   5180 C  C   . HIS C 1 88  ? -32.995 23.925  26.163  1   69.78  ? 84  HIS C C   1 
ATOM   5181 O  O   . HIS C 1 88  ? -32.165 24.448  26.911  1   68.34  ? 84  HIS C O   1 
ATOM   5182 C  CB  . HIS C 1 88  ? -33.074 24.6    23.711  1   81.69  ? 84  HIS C CB  1 
ATOM   5183 C  CG  . HIS C 1 88  ? -32.716 25.985  24.082  1   96.65  ? 84  HIS C CG  1 
ATOM   5184 N  ND1 . HIS C 1 88  ? -33.62  26.894  24.593  1   104.53 ? 84  HIS C ND1 1 
ATOM   5185 C  CD2 . HIS C 1 88  ? -31.534 26.601  24.008  1   102.58 ? 84  HIS C CD2 1 
ATOM   5186 C  CE1 . HIS C 1 88  ? -32.987 28.036  24.812  1   120.78 ? 84  HIS C CE1 1 
ATOM   5187 N  NE2 . HIS C 1 88  ? -31.719 27.879  24.461  1   117.17 ? 84  HIS C NE2 1 
ATOM   5188 N  N   . GLN C 1 89  ? -34.28  23.699  26.515  1   64     ? 85  GLN C N   1 
ATOM   5189 C  CA  . GLN C 1 89  ? -34.802 23.91   27.864  1   60.35  ? 85  GLN C CA  1 
ATOM   5190 C  C   . GLN C 1 89  ? -36.157 23.222  28.038  1   57.83  ? 85  GLN C C   1 
ATOM   5191 O  O   . GLN C 1 89  ? -36.647 22.569  27.123  1   59.52  ? 85  GLN C O   1 
ATOM   5192 C  CB  . GLN C 1 89  ? -34.909 25.378  28.269  1   61.01  ? 85  GLN C CB  1 
ATOM   5193 C  CG  . GLN C 1 89  ? -35.826 26.194  27.367  1   65.58  ? 85  GLN C CG  1 
ATOM   5194 C  CD  . GLN C 1 89  ? -35.859 27.637  27.807  1   70.83  ? 85  GLN C CD  1 
ATOM   5195 O  OE1 . GLN C 1 89  ? -35.107 28.046  28.698  1   70.65  ? 85  GLN C OE1 1 
ATOM   5196 N  NE2 . GLN C 1 89  ? -36.74  28.415  27.198  1   74.65  ? 85  GLN C NE2 1 
ATOM   5197 N  N   . ASP C 1 90  ? -36.741 23.368  29.237  1   56.43  ? 86  ASP C N   1 
ATOM   5198 C  CA  . ASP C 1 90  ? -38.011 22.768  29.626  1   56.06  ? 86  ASP C CA  1 
ATOM   5199 C  C   . ASP C 1 90  ? -39.12  23.832  29.6    1   56.58  ? 86  ASP C C   1 
ATOM   5200 O  O   . ASP C 1 90  ? -38.846 25.023  29.695  1   57.22  ? 86  ASP C O   1 
ATOM   5201 C  CB  . ASP C 1 90  ? -37.894 22.165  31.018  1   54.22  ? 86  ASP C CB  1 
ATOM   5202 C  CG  . ASP C 1 90  ? -37.672 23.191  32.114  1   56.8   ? 86  ASP C CG  1 
ATOM   5203 O  OD1 . ASP C 1 90  ? -38.632 23.927  32.436  1   59.29  ? 86  ASP C OD1 1 
ATOM   5204 O  OD2 . ASP C 1 90  ? -36.528 23.278  32.594  1   64.54  ? 86  ASP C OD2 1 
ATOM   5205 N  N   . LEU C 1 91  ? -40.383 23.396  29.548  1   51.56  ? 87  LEU C N   1 
ATOM   5206 C  CA  . LEU C 1 91  ? -41.511 24.277  29.296  1   51.65  ? 87  LEU C CA  1 
ATOM   5207 C  C   . LEU C 1 91  ? -41.668 25.272  30.446  1   54.6   ? 87  LEU C C   1 
ATOM   5208 O  O   . LEU C 1 91  ? -42.084 26.409  30.241  1   58.4   ? 87  LEU C O   1 
ATOM   5209 C  CB  . LEU C 1 91  ? -42.737 23.381  29.109  1   48.31  ? 87  LEU C CB  1 
ATOM   5210 C  CG  . LEU C 1 91  ? -44.032 24.073  28.663  1   46.57  ? 87  LEU C CG  1 
ATOM   5211 C  CD1 . LEU C 1 91  ? -43.895 24.695  27.279  1   46.97  ? 87  LEU C CD1 1 
ATOM   5212 C  CD2 . LEU C 1 91  ? -45.202 23.089  28.694  1   43.16  ? 87  LEU C CD2 1 
ATOM   5213 N  N   . LYS C 1 92  ? -41.32  24.849  31.662  1   54.1   ? 88  LYS C N   1 
ATOM   5214 C  CA  . LYS C 1 92  ? -41.376 25.724  32.825  1   57.77  ? 88  LYS C CA  1 
ATOM   5215 C  C   . LYS C 1 92  ? -40.452 26.926  32.629  1   59.39  ? 88  LYS C C   1 
ATOM   5216 O  O   . LYS C 1 92  ? -40.833 28.059  32.919  1   63.13  ? 88  LYS C O   1 
ATOM   5217 C  CB  . LYS C 1 92  ? -41.096 24.933  34.108  1   53.26  ? 88  LYS C CB  1 
ATOM   5218 C  CG  . LYS C 1 92  ? -40.951 25.732  35.386  1   63.21  ? 88  LYS C CG  1 
ATOM   5219 C  CD  . LYS C 1 92  ? -42.002 26.792  35.704  1   73.93  ? 88  LYS C CD  1 
ATOM   5220 C  CE  . LYS C 1 92  ? -43.417 26.288  35.714  1   85.88  ? 88  LYS C CE  1 
ATOM   5221 N  NZ  . LYS C 1 92  ? -44.384 27.361  35.978  1   89.79  ? 88  LYS C NZ  1 
ATOM   5222 N  N   . LYS C 1 93  ? -39.23  26.678  32.147  1   58.12  ? 89  LYS C N   1 
ATOM   5223 C  CA  . LYS C 1 93  ? -38.286 27.762  31.931  1   57.88  ? 89  LYS C CA  1 
ATOM   5224 C  C   . LYS C 1 93  ? -38.823 28.68   30.842  1   54.7   ? 89  LYS C C   1 
ATOM   5225 O  O   . LYS C 1 93  ? -38.718 29.899  30.964  1   51.56  ? 89  LYS C O   1 
ATOM   5226 C  CB  . LYS C 1 93  ? -36.88  27.243  31.614  1   61.6   ? 89  LYS C CB  1 
ATOM   5227 C  CG  . LYS C 1 93  ? -36.063 26.881  32.854  1   68.91  ? 89  LYS C CG  1 
ATOM   5228 C  CD  . LYS C 1 93  ? -34.623 26.546  32.485  1   81.77  ? 89  LYS C CD  1 
ATOM   5229 C  CE  . LYS C 1 93  ? -33.775 26.206  33.665  1   86.04  ? 89  LYS C CE  1 
ATOM   5230 N  NZ  . LYS C 1 93  ? -32.383 26.553  33.362  1   91.89  ? 89  LYS C NZ  1 
ATOM   5231 N  N   . PHE C 1 94  ? -39.398 28.064  29.796  1   52.57  ? 90  PHE C N   1 
ATOM   5232 C  CA  . PHE C 1 94  ? -40.001 28.792  28.69   1   56.45  ? 90  PHE C CA  1 
ATOM   5233 C  C   . PHE C 1 94  ? -41.121 29.711  29.2    1   61.7   ? 90  PHE C C   1 
ATOM   5234 O  O   . PHE C 1 94  ? -41.029 30.948  29.072  1   60.72  ? 90  PHE C O   1 
ATOM   5235 C  CB  . PHE C 1 94  ? -40.434 27.818  27.594  1   53.02  ? 90  PHE C CB  1 
ATOM   5236 C  CG  . PHE C 1 94  ? -40.974 28.526  26.364  1   55.29  ? 90  PHE C CG  1 
ATOM   5237 C  CD1 . PHE C 1 94  ? -40.204 29.487  25.7    1   57.38  ? 90  PHE C CD1 1 
ATOM   5238 C  CD2 . PHE C 1 94  ? -42.277 28.28   25.922  1   54.49  ? 90  PHE C CD2 1 
ATOM   5239 C  CE1 . PHE C 1 94  ? -40.722 30.157  24.594  1   56.41  ? 90  PHE C CE1 1 
ATOM   5240 C  CE2 . PHE C 1 94  ? -42.782 28.938  24.805  1   55.21  ? 90  PHE C CE2 1 
ATOM   5241 C  CZ  . PHE C 1 94  ? -41.998 29.871  24.143  1   56.07  ? 90  PHE C CZ  1 
ATOM   5242 N  N   . MET C 1 95  ? -42.161 29.092  29.796  1   58.53  ? 91  MET C N   1 
ATOM   5243 C  CA  . MET C 1 95  ? -43.285 29.818  30.384  1   60.36  ? 91  MET C CA  1 
ATOM   5244 C  C   . MET C 1 95  ? -42.801 31.056  31.146  1   58.48  ? 91  MET C C   1 
ATOM   5245 O  O   . MET C 1 95  ? -43.241 32.162  30.861  1   60.02  ? 91  MET C O   1 
ATOM   5246 C  CB  . MET C 1 95  ? -44.187 28.914  31.237  1   58.28  ? 91  MET C CB  1 
ATOM   5247 C  CG  . MET C 1 95  ? -45.096 28.012  30.407  1   60.41  ? 91  MET C CG  1 
ATOM   5248 S  SD  . MET C 1 95  ? -46.139 26.781  31.233  1   68.38  ? 91  MET C SD  1 
ATOM   5249 C  CE  . MET C 1 95  ? -45.06  26.028  32.449  1   58.09  ? 91  MET C CE  1 
ATOM   5250 N  N   . ASP C 1 96  ? -41.846 30.872  32.06   1   55.39  ? 92  ASP C N   1 
ATOM   5251 C  CA  . ASP C 1 96  ? -41.308 31.941  32.883  1   58.15  ? 92  ASP C CA  1 
ATOM   5252 C  C   . ASP C 1 96  ? -40.701 33.054  32.025  1   61.2   ? 92  ASP C C   1 
ATOM   5253 O  O   . ASP C 1 96  ? -40.948 34.234  32.277  1   61.37  ? 92  ASP C O   1 
ATOM   5254 C  CB  . ASP C 1 96  ? -40.346 31.395  33.919  1   57.96  ? 92  ASP C CB  1 
ATOM   5255 C  CG  . ASP C 1 96  ? -41.025 30.594  35.014  1   64.11  ? 92  ASP C CG  1 
ATOM   5256 O  OD1 . ASP C 1 96  ? -42.274 30.596  35.042  1   66.85  ? 92  ASP C OD1 1 
ATOM   5257 O  OD2 . ASP C 1 96  ? -40.305 29.952  35.808  1   73.8   ? 92  ASP C OD2 1 
ATOM   5258 N  N   . ALA C 1 97  ? -39.894 32.691  31.02   1   59.81  ? 93  ALA C N   1 
ATOM   5259 C  CA  . ALA C 1 97  ? -39.265 33.695  30.172  1   58.27  ? 93  ALA C CA  1 
ATOM   5260 C  C   . ALA C 1 97  ? -40.346 34.48   29.441  1   60.53  ? 93  ALA C C   1 
ATOM   5261 O  O   . ALA C 1 97  ? -40.106 35.616  29.047  1   65.46  ? 93  ALA C O   1 
ATOM   5262 C  CB  . ALA C 1 97  ? -38.337 33.049  29.177  1   54.75  ? 93  ALA C CB  1 
ATOM   5263 N  N   . SER C 1 98  ? -41.517 33.851  29.258  1   62.72  ? 94  SER C N   1 
ATOM   5264 C  CA  . SER C 1 98  ? -42.636 34.386  28.492  1   66.57  ? 94  SER C CA  1 
ATOM   5265 C  C   . SER C 1 98  ? -43.74  34.911  29.417  1   72.29  ? 94  SER C C   1 
ATOM   5266 O  O   . SER C 1 98  ? -44.855 35.167  28.956  1   75     ? 94  SER C O   1 
ATOM   5267 C  CB  . SER C 1 98  ? -43.201 33.334  27.547  1   60.8   ? 94  SER C CB  1 
ATOM   5268 O  OG  . SER C 1 98  ? -42.196 32.757  26.726  1   64.22  ? 94  SER C OG  1 
ATOM   5269 N  N   . ALA C 1 99  ? -43.433 35.092  30.711  1   72.32  ? 95  ALA C N   1 
ATOM   5270 C  CA  . ALA C 1 99  ? -44.447 35.493  31.678  1   71.89  ? 95  ALA C CA  1 
ATOM   5271 C  C   . ALA C 1 99  ? -45.052 36.864  31.349  1   73.06  ? 95  ALA C C   1 
ATOM   5272 O  O   . ALA C 1 99  ? -46.269 37.019  31.473  1   73.91  ? 95  ALA C O   1 
ATOM   5273 C  CB  . ALA C 1 99  ? -43.896 35.432  33.081  1   75.84  ? 95  ALA C CB  1 
ATOM   5274 N  N   . LEU C 1 100 ? -44.227 37.808  30.865  1   67.58  ? 96  LEU C N   1 
ATOM   5275 C  CA  . LEU C 1 100 ? -44.686 39.131  30.46   1   71.76  ? 96  LEU C CA  1 
ATOM   5276 C  C   . LEU C 1 100 ? -45.219 39.172  29.021  1   75.66  ? 96  LEU C C   1 
ATOM   5277 O  O   . LEU C 1 100 ? -46.296 39.735  28.819  1   81.01  ? 96  LEU C O   1 
ATOM   5278 C  CB  . LEU C 1 100 ? -43.599 40.18   30.679  1   70.41  ? 96  LEU C CB  1 
ATOM   5279 C  CG  . LEU C 1 100 ? -42.906 40.125  32.039  1   68.56  ? 96  LEU C CG  1 
ATOM   5280 C  CD1 . LEU C 1 100 ? -41.973 41.279  32.269  1   66.85  ? 96  LEU C CD1 1 
ATOM   5281 C  CD2 . LEU C 1 100 ? -43.962 40.105  33.117  1   70.95  ? 96  LEU C CD2 1 
ATOM   5282 N  N   . THR C 1 101 ? -44.463 38.645  28.031  1   73.24  ? 97  THR C N   1 
ATOM   5283 C  CA  . THR C 1 101 ? -44.817 38.71   26.606  1   76.46  ? 97  THR C CA  1 
ATOM   5284 C  C   . THR C 1 101 ? -45.99  37.79   26.261  1   76.25  ? 97  THR C C   1 
ATOM   5285 O  O   . THR C 1 101 ? -46.773 38.079  25.362  1   80.22  ? 97  THR C O   1 
ATOM   5286 C  CB  . THR C 1 101 ? -43.666 38.379  25.646  1   77.52  ? 97  THR C CB  1 
ATOM   5287 O  OG1 . THR C 1 101 ? -43.396 36.971  25.667  1   78.44  ? 97  THR C OG1 1 
ATOM   5288 C  CG2 . THR C 1 101 ? -42.434 39.223  25.906  1   75.31  ? 97  THR C CG2 1 
ATOM   5289 N  N   . GLY C 1 102 ? -46.068 36.639  26.924  1   74.65  ? 98  GLY C N   1 
ATOM   5290 C  CA  . GLY C 1 102 ? -47.041 35.628  26.555  1   72.6   ? 98  GLY C CA  1 
ATOM   5291 C  C   . GLY C 1 102 ? -46.476 34.728  25.465  1   72.36  ? 98  GLY C C   1 
ATOM   5292 O  O   . GLY C 1 102 ? -45.472 35.065  24.829  1   72.95  ? 98  GLY C O   1 
ATOM   5293 N  N   . ILE C 1 103 ? -47.15  33.585  25.286  1   69.18  ? 99  ILE C N   1 
ATOM   5294 C  CA  . ILE C 1 103 ? -46.85  32.602  24.261  1   68.75  ? 99  ILE C CA  1 
ATOM   5295 C  C   . ILE C 1 103 ? -47.898 32.713  23.149  1   69.96  ? 99  ILE C C   1 
ATOM   5296 O  O   . ILE C 1 103 ? -49.084 32.531  23.401  1   71.59  ? 99  ILE C O   1 
ATOM   5297 C  CB  . ILE C 1 103 ? -46.879 31.197  24.893  1   65.65  ? 99  ILE C CB  1 
ATOM   5298 C  CG1 . ILE C 1 103 ? -45.943 31.091  26.092  1   65.4   ? 99  ILE C CG1 1 
ATOM   5299 C  CG2 . ILE C 1 103 ? -46.603 30.102  23.859  1   64.03  ? 99  ILE C CG2 1 
ATOM   5300 C  CD1 . ILE C 1 103 ? -45.964 29.728  26.774  1   57.25  ? 99  ILE C CD1 1 
ATOM   5301 N  N   . PRO C 1 104 ? -47.514 32.959  21.875  1   71.28  ? 100 PRO C N   1 
ATOM   5302 C  CA  . PRO C 1 104 ? -48.497 33.012  20.793  1   69.34  ? 100 PRO C CA  1 
ATOM   5303 C  C   . PRO C 1 104 ? -49.381 31.763  20.782  1   68.65  ? 100 PRO C C   1 
ATOM   5304 O  O   . PRO C 1 104 ? -48.9   30.637  20.954  1   64.09  ? 100 PRO C O   1 
ATOM   5305 C  CB  . PRO C 1 104 ? -47.591 33.121  19.543  1   71.1   ? 100 PRO C CB  1 
ATOM   5306 C  CG  . PRO C 1 104 ? -46.336 33.795  20.032  1   67.5   ? 100 PRO C CG  1 
ATOM   5307 C  CD  . PRO C 1 104 ? -46.131 33.182  21.409  1   72.32  ? 100 PRO C CD  1 
ATOM   5308 N  N   . LEU C 1 105 ? -50.679 31.986  20.549  1   71.64  ? 101 LEU C N   1 
ATOM   5309 C  CA  . LEU C 1 105 ? -51.689 30.935  20.473  1   81.57  ? 101 LEU C CA  1 
ATOM   5310 C  C   . LEU C 1 105 ? -51.274 29.783  19.54   1   77.98  ? 101 LEU C C   1 
ATOM   5311 O  O   . LEU C 1 105 ? -51.49  28.614  19.868  1   77.22  ? 101 LEU C O   1 
ATOM   5312 C  CB  . LEU C 1 105 ? -53.033 31.575  20.104  1   89.26  ? 101 LEU C CB  1 
ATOM   5313 C  CG  . LEU C 1 105 ? -54.316 30.786  20.413  1   94.14  ? 101 LEU C CG  1 
ATOM   5314 C  CD1 . LEU C 1 105 ? -54.67  29.71   19.381  1   94.46  ? 101 LEU C CD1 1 
ATOM   5315 C  CD2 . LEU C 1 105 ? -54.245 30.181  21.8    1   97.52  ? 101 LEU C CD2 1 
ATOM   5316 N  N   . PRO C 1 106 ? -50.692 30.035  18.344  1   76.78  ? 102 PRO C N   1 
ATOM   5317 C  CA  . PRO C 1 106 ? -50.276 28.937  17.468  1   74.37  ? 102 PRO C CA  1 
ATOM   5318 C  C   . PRO C 1 106 ? -49.198 28.035  18.058  1   72.06  ? 102 PRO C C   1 
ATOM   5319 O  O   . PRO C 1 106 ? -49.24  26.833  17.817  1   73.42  ? 102 PRO C O   1 
ATOM   5320 C  CB  . PRO C 1 106 ? -49.852 29.572  16.119  1   75.48  ? 102 PRO C CB  1 
ATOM   5321 C  CG  . PRO C 1 106 ? -50.35  31.012  16.221  1   77.45  ? 102 PRO C CG  1 
ATOM   5322 C  CD  . PRO C 1 106 ? -50.47  31.351  17.717  1   78     ? 102 PRO C CD  1 
ATOM   5323 N  N   . LEU C 1 107 ? -48.262 28.61   18.833  1   68.46  ? 103 LEU C N   1 
ATOM   5324 C  CA  . LEU C 1 107 ? -47.204 27.837  19.469  1   65.32  ? 103 LEU C CA  1 
ATOM   5325 C  C   . LEU C 1 107 ? -47.829 26.918  20.525  1   63.16  ? 103 LEU C C   1 
ATOM   5326 O  O   . LEU C 1 107 ? -47.607 25.701  20.515  1   60.88  ? 103 LEU C O   1 
ATOM   5327 C  CB  . LEU C 1 107 ? -46.1   28.734  20.039  1   63.82  ? 103 LEU C CB  1 
ATOM   5328 C  CG  . LEU C 1 107 ? -44.829 28.015  20.519  1   65.68  ? 103 LEU C CG  1 
ATOM   5329 C  CD1 . LEU C 1 107 ? -44.209 27.17   19.409  1   63.52  ? 103 LEU C CD1 1 
ATOM   5330 C  CD2 . LEU C 1 107 ? -43.781 28.985  21.07   1   63.32  ? 103 LEU C CD2 1 
ATOM   5331 N  N   . ILE C 1 108 ? -48.643 27.525  21.402  1   60.02  ? 104 ILE C N   1 
ATOM   5332 C  CA  . ILE C 1 108 ? -49.437 26.81   22.389  1   61.46  ? 104 ILE C CA  1 
ATOM   5333 C  C   . ILE C 1 108 ? -50.086 25.59   21.734  1   63.03  ? 104 ILE C C   1 
ATOM   5334 O  O   . ILE C 1 108 ? -49.841 24.455  22.146  1   66.11  ? 104 ILE C O   1 
ATOM   5335 C  CB  . ILE C 1 108 ? -50.476 27.73   23.069  1   58.78  ? 104 ILE C CB  1 
ATOM   5336 C  CG1 . ILE C 1 108 ? -49.807 28.905  23.794  1   56.02  ? 104 ILE C CG1 1 
ATOM   5337 C  CG2 . ILE C 1 108 ? -51.384 26.917  24.004  1   52.51  ? 104 ILE C CG2 1 
ATOM   5338 C  CD1 . ILE C 1 108 ? -50.761 29.879  24.476  1   54.97  ? 104 ILE C CD1 1 
ATOM   5339 N  N   . LYS C 1 109 ? -50.886 25.833  20.691  1   64.46  ? 105 LYS C N   1 
ATOM   5340 C  CA  . LYS C 1 109 ? -51.643 24.785  20.015  1   65.25  ? 105 LYS C CA  1 
ATOM   5341 C  C   . LYS C 1 109 ? -50.724 23.697  19.448  1   61.9   ? 105 LYS C C   1 
ATOM   5342 O  O   . LYS C 1 109 ? -51.071 22.514  19.475  1   60.87  ? 105 LYS C O   1 
ATOM   5343 C  CB  . LYS C 1 109 ? -52.477 25.428  18.901  1   67.9   ? 105 LYS C CB  1 
ATOM   5344 C  CG  . LYS C 1 109 ? -53.394 24.497  18.118  1   67.75  ? 105 LYS C CG  1 
ATOM   5345 C  CD  . LYS C 1 109 ? -54.105 25.268  17.014  1   72.94  ? 105 LYS C CD  1 
ATOM   5346 C  CE  . LYS C 1 109 ? -54.9   26.478  17.467  1   71.03  ? 105 LYS C CE  1 
ATOM   5347 N  NZ  . LYS C 1 109 ? -55.716 26.946  16.344  1   67.82  ? 105 LYS C NZ  1 
ATOM   5348 N  N   . SER C 1 110 ? -49.574 24.11   18.893  1   60.53  ? 106 SER C N   1 
ATOM   5349 C  CA  . SER C 1 110 ? -48.608 23.18   18.333  1   60.93  ? 106 SER C CA  1 
ATOM   5350 C  C   . SER C 1 110 ? -48.07  22.291  19.45   1   60.47  ? 106 SER C C   1 
ATOM   5351 O  O   . SER C 1 110 ? -47.975 21.069  19.289  1   59.81  ? 106 SER C O   1 
ATOM   5352 C  CB  . SER C 1 110 ? -47.488 23.905  17.622  1   63.63  ? 106 SER C CB  1 
ATOM   5353 O  OG  . SER C 1 110 ? -46.462 23.013  17.193  1   66.12  ? 106 SER C OG  1 
ATOM   5354 N  N   . TYR C 1 111 ? -47.747 22.925  20.585  1   54.45  ? 107 TYR C N   1 
ATOM   5355 C  CA  . TYR C 1 111 ? -47.14  22.223  21.704  1   57.61  ? 107 TYR C CA  1 
ATOM   5356 C  C   . TYR C 1 111 ? -48.114 21.192  22.272  1   59.51  ? 107 TYR C C   1 
ATOM   5357 O  O   . TYR C 1 111 ? -47.739 20.037  22.5    1   63.57  ? 107 TYR C O   1 
ATOM   5358 C  CB  . TYR C 1 111 ? -46.646 23.191  22.781  1   55.49  ? 107 TYR C CB  1 
ATOM   5359 C  CG  . TYR C 1 111 ? -45.293 23.846  22.548  1   55.17  ? 107 TYR C CG  1 
ATOM   5360 C  CD1 . TYR C 1 111 ? -44.401 23.398  21.561  1   54.56  ? 107 TYR C CD1 1 
ATOM   5361 C  CD2 . TYR C 1 111 ? -44.906 24.917  23.347  1   51.37  ? 107 TYR C CD2 1 
ATOM   5362 C  CE1 . TYR C 1 111 ? -43.164 24.009  21.371  1   56.2   ? 107 TYR C CE1 1 
ATOM   5363 C  CE2 . TYR C 1 111 ? -43.673 25.521  23.17   1   55.27  ? 107 TYR C CE2 1 
ATOM   5364 C  CZ  . TYR C 1 111 ? -42.802 25.077  22.185  1   58.17  ? 107 TYR C CZ  1 
ATOM   5365 O  OH  . TYR C 1 111 ? -41.594 25.714  22.077  1   59.02  ? 107 TYR C OH  1 
ATOM   5366 N  N   . LEU C 1 112 ? -49.364 21.617  22.486  1   58.82  ? 108 LEU C N   1 
ATOM   5367 C  CA  . LEU C 1 112 ? -50.379 20.735  23.034  1   57.39  ? 108 LEU C CA  1 
ATOM   5368 C  C   . LEU C 1 112 ? -50.58  19.551  22.088  1   57.16  ? 108 LEU C C   1 
ATOM   5369 O  O   . LEU C 1 112 ? -50.734 18.427  22.552  1   55.84  ? 108 LEU C O   1 
ATOM   5370 C  CB  . LEU C 1 112 ? -51.686 21.486  23.292  1   57.67  ? 108 LEU C CB  1 
ATOM   5371 C  CG  . LEU C 1 112 ? -52.813 20.661  23.928  1   58.07  ? 108 LEU C CG  1 
ATOM   5372 C  CD1 . LEU C 1 112 ? -52.415 20.145  25.285  1   57.83  ? 108 LEU C CD1 1 
ATOM   5373 C  CD2 . LEU C 1 112 ? -54.077 21.466  24.079  1   61.15  ? 108 LEU C CD2 1 
ATOM   5374 N  N   . PHE C 1 113 ? -50.556 19.813  20.77   1   56.22  ? 109 PHE C N   1 
ATOM   5375 C  CA  . PHE C 1 113 ? -50.771 18.783  19.764  1   61.51  ? 109 PHE C CA  1 
ATOM   5376 C  C   . PHE C 1 113 ? -49.678 17.718  19.877  1   65.26  ? 109 PHE C C   1 
ATOM   5377 O  O   . PHE C 1 113 ? -49.956 16.517  19.98   1   65.57  ? 109 PHE C O   1 
ATOM   5378 C  CB  . PHE C 1 113 ? -50.839 19.446  18.385  1   64.13  ? 109 PHE C CB  1 
ATOM   5379 C  CG  . PHE C 1 113 ? -51.342 18.58   17.238  1   66     ? 109 PHE C CG  1 
ATOM   5380 C  CD1 . PHE C 1 113 ? -52.631 18.038  17.263  1   67.01  ? 109 PHE C CD1 1 
ATOM   5381 C  CD2 . PHE C 1 113 ? -50.543 18.353  16.112  1   65.66  ? 109 PHE C CD2 1 
ATOM   5382 C  CE1 . PHE C 1 113 ? -53.091 17.253  16.21   1   67.88  ? 109 PHE C CE1 1 
ATOM   5383 C  CE2 . PHE C 1 113 ? -51.003 17.553  15.065  1   64.02  ? 109 PHE C CE2 1 
ATOM   5384 C  CZ  . PHE C 1 113 ? -52.266 16.993  15.124  1   64.73  ? 109 PHE C CZ  1 
ATOM   5385 N  N   . GLN C 1 114 ? -48.426 18.189  19.905  1   66.42  ? 110 GLN C N   1 
ATOM   5386 C  CA  . GLN C 1 114 ? -47.254 17.334  20.043  1   64.81  ? 110 GLN C CA  1 
ATOM   5387 C  C   . GLN C 1 114 ? -47.291 16.547  21.356  1   58.88  ? 110 GLN C C   1 
ATOM   5388 O  O   . GLN C 1 114 ? -46.894 15.383  21.387  1   57.09  ? 110 GLN C O   1 
ATOM   5389 C  CB  . GLN C 1 114 ? -45.988 18.182  19.93   1   60.64  ? 110 GLN C CB  1 
ATOM   5390 C  CG  . GLN C 1 114 ? -45.741 18.78   18.551  1   55.98  ? 110 GLN C CG  1 
ATOM   5391 C  CD  . GLN C 1 114 ? -44.436 19.543  18.52   1   60.97  ? 110 GLN C CD  1 
ATOM   5392 O  OE1 . GLN C 1 114 ? -43.356 18.937  18.573  1   62.52  ? 110 GLN C OE1 1 
ATOM   5393 N  NE2 . GLN C 1 114 ? -44.525 20.871  18.483  1   53.96  ? 110 GLN C NE2 1 
ATOM   5394 N  N   . LEU C 1 115 ? -47.75  17.194  22.436  1   56.28  ? 111 LEU C N   1 
ATOM   5395 C  CA  . LEU C 1 115 ? -47.787 16.584  23.756  1   52.26  ? 111 LEU C CA  1 
ATOM   5396 C  C   . LEU C 1 115 ? -48.795 15.44   23.758  1   53.2   ? 111 LEU C C   1 
ATOM   5397 O  O   . LEU C 1 115 ? -48.598 14.445  24.439  1   53.14  ? 111 LEU C O   1 
ATOM   5398 C  CB  . LEU C 1 115 ? -48.155 17.621  24.814  1   49     ? 111 LEU C CB  1 
ATOM   5399 C  CG  . LEU C 1 115 ? -47.06  18.612  25.21   1   46.94  ? 111 LEU C CG  1 
ATOM   5400 C  CD1 . LEU C 1 115 ? -47.561 19.599  26.237  1   43.09  ? 111 LEU C CD1 1 
ATOM   5401 C  CD2 . LEU C 1 115 ? -45.875 17.858  25.774  1   48.25  ? 111 LEU C CD2 1 
ATOM   5402 N  N   . LEU C 1 116 ? -49.891 15.606  23.008  1   53.89  ? 112 LEU C N   1 
ATOM   5403 C  CA  . LEU C 1 116 ? -50.96  14.629  22.982  1   55.23  ? 112 LEU C CA  1 
ATOM   5404 C  C   . LEU C 1 116 ? -50.557 13.435  22.119  1   62.32  ? 112 LEU C C   1 
ATOM   5405 O  O   . LEU C 1 116 ? -51.021 12.313  22.36   1   60.56  ? 112 LEU C O   1 
ATOM   5406 C  CB  . LEU C 1 116 ? -52.18  15.339  22.413  1   54.55  ? 112 LEU C CB  1 
ATOM   5407 C  CG  . LEU C 1 116 ? -52.947 16.203  23.409  1   57.14  ? 112 LEU C CG  1 
ATOM   5408 C  CD1 . LEU C 1 116 ? -53.826 17.179  22.668  1   61.12  ? 112 LEU C CD1 1 
ATOM   5409 C  CD2 . LEU C 1 116 ? -53.78  15.337  24.33   1   59.56  ? 112 LEU C CD2 1 
ATOM   5410 N  N   . GLN C 1 117 ? -49.736 13.712  21.089  1   62.47  ? 113 GLN C N   1 
ATOM   5411 C  CA  . GLN C 1 117 ? -49.217 12.699  20.183  1   63.54  ? 113 GLN C CA  1 
ATOM   5412 C  C   . GLN C 1 117 ? -48.244 11.809  20.95   1   61.72  ? 113 GLN C C   1 
ATOM   5413 O  O   . GLN C 1 117 ? -48.353 10.586  20.908  1   63.56  ? 113 GLN C O   1 
ATOM   5414 C  CB  . GLN C 1 117 ? -48.517 13.34   18.985  1   62.34  ? 113 GLN C CB  1 
ATOM   5415 C  CG  . GLN C 1 117 ? -49.487 13.933  17.979  1   64.96  ? 113 GLN C CG  1 
ATOM   5416 C  CD  . GLN C 1 117 ? -48.847 14.209  16.641  1   73.65  ? 113 GLN C CD  1 
ATOM   5417 O  OE1 . GLN C 1 117 ? -49.149 13.518  15.67   1   83.07  ? 113 GLN C OE1 1 
ATOM   5418 N  NE2 . GLN C 1 117 ? -47.954 15.19   16.557  1   76.55  ? 113 GLN C NE2 1 
ATOM   5419 N  N   . GLY C 1 118 ? -47.293 12.457  21.632  1   58.3   ? 114 GLY C N   1 
ATOM   5420 C  CA  . GLY C 1 118 ? -46.412 11.807  22.581  1   52.04  ? 114 GLY C CA  1 
ATOM   5421 C  C   . GLY C 1 118 ? -47.193 10.911  23.534  1   53.11  ? 114 GLY C C   1 
ATOM   5422 O  O   . GLY C 1 118 ? -46.886 9.727   23.669  1   53.94  ? 114 GLY C O   1 
ATOM   5423 N  N   . LEU C 1 119 ? -48.226 11.478  24.166  1   53.32  ? 115 LEU C N   1 
ATOM   5424 C  CA  . LEU C 1 119 ? -48.936 10.77   25.222  1   52.87  ? 115 LEU C CA  1 
ATOM   5425 C  C   . LEU C 1 119 ? -49.759 9.603   24.661  1   50.34  ? 115 LEU C C   1 
ATOM   5426 O  O   . LEU C 1 119 ? -49.815 8.539   25.279  1   49.72  ? 115 LEU C O   1 
ATOM   5427 C  CB  . LEU C 1 119 ? -49.761 11.741  26.065  1   47.81  ? 115 LEU C CB  1 
ATOM   5428 C  CG  . LEU C 1 119 ? -50.484 11.115  27.257  1   48.99  ? 115 LEU C CG  1 
ATOM   5429 C  CD1 . LEU C 1 119 ? -49.477 10.569  28.246  1   47.19  ? 115 LEU C CD1 1 
ATOM   5430 C  CD2 . LEU C 1 119 ? -51.409 12.12   27.93   1   52.37  ? 115 LEU C CD2 1 
ATOM   5431 N  N   . ALA C 1 120 ? -50.414 9.829   23.514  1   49     ? 116 ALA C N   1 
ATOM   5432 C  CA  . ALA C 1 120 ? -51.159 8.818   22.773  1   54.92  ? 116 ALA C CA  1 
ATOM   5433 C  C   . ALA C 1 120 ? -50.29  7.575   22.53   1   59.84  ? 116 ALA C C   1 
ATOM   5434 O  O   . ALA C 1 120 ? -50.735 6.446   22.75   1   58.47  ? 116 ALA C O   1 
ATOM   5435 C  CB  . ALA C 1 120 ? -51.666 9.407   21.472  1   48.7   ? 116 ALA C CB  1 
ATOM   5436 N  N   . PHE C 1 121 ? -49.032 7.808   22.115  1   57.67  ? 117 PHE C N   1 
ATOM   5437 C  CA  . PHE C 1 121 ? -48.03  6.779   21.893  1   58.63  ? 117 PHE C CA  1 
ATOM   5438 C  C   . PHE C 1 121 ? -47.731 6.01    23.182  1   58.17  ? 117 PHE C C   1 
ATOM   5439 O  O   . PHE C 1 121 ? -47.715 4.783   23.166  1   66.65  ? 117 PHE C O   1 
ATOM   5440 C  CB  . PHE C 1 121 ? -46.785 7.413   21.266  1   60.42  ? 117 PHE C CB  1 
ATOM   5441 C  CG  . PHE C 1 121 ? -45.853 6.394   20.625  1   64.68  ? 117 PHE C CG  1 
ATOM   5442 C  CD1 . PHE C 1 121 ? -44.942 5.668   21.399  1   59.48  ? 117 PHE C CD1 1 
ATOM   5443 C  CD2 . PHE C 1 121 ? -45.914 6.132   19.256  1   61.67  ? 117 PHE C CD2 1 
ATOM   5444 C  CE1 . PHE C 1 121 ? -44.099 4.735   20.811  1   53.68  ? 117 PHE C CE1 1 
ATOM   5445 C  CE2 . PHE C 1 121 ? -45.064 5.196   18.679  1   58.62  ? 117 PHE C CE2 1 
ATOM   5446 C  CZ  . PHE C 1 121 ? -44.163 4.499   19.455  1   54.1   ? 117 PHE C CZ  1 
ATOM   5447 N  N   . CYS C 1 122 ? -47.499 6.719   24.296  1   52.34  ? 118 CYS C N   1 
ATOM   5448 C  CA  . CYS C 1 122 ? -47.329 6.062   25.584  1   51.04  ? 118 CYS C CA  1 
ATOM   5449 C  C   . CYS C 1 122 ? -48.49  5.133   25.916  1   51.74  ? 118 CYS C C   1 
ATOM   5450 O  O   . CYS C 1 122 ? -48.268 3.987   26.283  1   52.34  ? 118 CYS C O   1 
ATOM   5451 C  CB  . CYS C 1 122 ? -47.214 7.058   26.72   1   48.41  ? 118 CYS C CB  1 
ATOM   5452 S  SG  . CYS C 1 122 ? -45.634 7.919   26.608  1   53.73  ? 118 CYS C SG  1 
ATOM   5453 N  N   . HIS C 1 123 ? -49.717 5.651   25.804  1   53.65  ? 119 HIS C N   1 
ATOM   5454 C  CA  . HIS C 1 123 ? -50.917 4.921   26.179  1   53.35  ? 119 HIS C CA  1 
ATOM   5455 C  C   . HIS C 1 123 ? -51.129 3.722   25.254  1   54.28  ? 119 HIS C C   1 
ATOM   5456 O  O   . HIS C 1 123 ? -51.445 2.631   25.729  1   56.48  ? 119 HIS C O   1 
ATOM   5457 C  CB  . HIS C 1 123 ? -52.103 5.883   26.333  1   55.78  ? 119 HIS C CB  1 
ATOM   5458 C  CG  . HIS C 1 123 ? -51.944 6.885   27.437  1   60.21  ? 119 HIS C CG  1 
ATOM   5459 N  ND1 . HIS C 1 123 ? -52.763 7.986   27.573  1   61.58  ? 119 HIS C ND1 1 
ATOM   5460 C  CD2 . HIS C 1 123 ? -51.071 6.958   28.46   1   61.1   ? 119 HIS C CD2 1 
ATOM   5461 C  CE1 . HIS C 1 123 ? -52.384 8.689   28.632  1   62     ? 119 HIS C CE1 1 
ATOM   5462 N  NE2 . HIS C 1 123 ? -51.356 8.084   29.185  1   62.87  ? 119 HIS C NE2 1 
ATOM   5463 N  N   . SER C 1 124 ? -50.973 3.954   23.94   1   56.45  ? 120 SER C N   1 
ATOM   5464 C  CA  . SER C 1 124 ? -50.972 2.936   22.897  1   57.11  ? 120 SER C CA  1 
ATOM   5465 C  C   . SER C 1 124 ? -50.004 1.806   23.225  1   58.45  ? 120 SER C C   1 
ATOM   5466 O  O   . SER C 1 124 ? -50.176 0.701   22.732  1   58.45  ? 120 SER C O   1 
ATOM   5467 C  CB  . SER C 1 124 ? -50.591 3.53    21.569  1   56.8   ? 120 SER C CB  1 
ATOM   5468 O  OG  . SER C 1 124 ? -51.697 4.191   20.977  1   65.48  ? 120 SER C OG  1 
ATOM   5469 N  N   . HIS C 1 125 ? -48.961 2.111   24.013  1   59.69  ? 121 HIS C N   1 
ATOM   5470 C  CA  . HIS C 1 125 ? -47.903 1.164   24.325  1   57.03  ? 121 HIS C CA  1 
ATOM   5471 C  C   . HIS C 1 125 ? -47.884 0.838   25.814  1   50.8   ? 121 HIS C C   1 
ATOM   5472 O  O   . HIS C 1 125 ? -46.822 0.556   26.336  1   47.49  ? 121 HIS C O   1 
ATOM   5473 C  CB  . HIS C 1 125 ? -46.553 1.69    23.82   1   57.4   ? 121 HIS C CB  1 
ATOM   5474 C  CG  . HIS C 1 125 ? -46.468 1.741   22.331  1   64.48  ? 121 HIS C CG  1 
ATOM   5475 N  ND1 . HIS C 1 125 ? -47.17  2.651   21.565  1   70.86  ? 121 HIS C ND1 1 
ATOM   5476 C  CD2 . HIS C 1 125 ? -45.791 0.98    21.473  1   66.38  ? 121 HIS C CD2 1 
ATOM   5477 C  CE1 . HIS C 1 125 ? -46.896 2.451   20.287  1   72.25  ? 121 HIS C CE1 1 
ATOM   5478 N  NE2 . HIS C 1 125 ? -46.063 1.438   20.212  1   76.9   ? 121 HIS C NE2 1 
ATOM   5479 N  N   . ARG C 1 126 ? -49.051 0.895   26.467  1   52.73  ? 122 ARG C N   1 
ATOM   5480 C  CA  . ARG C 1 126 ? -49.326 0.413   27.819  1   53.91  ? 122 ARG C CA  1 
ATOM   5481 C  C   . ARG C 1 126 ? -48.406 1.029   28.884  1   56.9   ? 122 ARG C C   1 
ATOM   5482 O  O   . ARG C 1 126 ? -48.128 0.392   29.899  1   60.33  ? 122 ARG C O   1 
ATOM   5483 C  CB  . ARG C 1 126 ? -49.432 -1.114  27.846  1   50.86  ? 122 ARG C CB  1 
ATOM   5484 C  CG  . ARG C 1 126 ? -48.186 -1.895  27.44   1   54.07  ? 122 ARG C CG  1 
ATOM   5485 C  CD  . ARG C 1 126 ? -47.218 -2.371  28.545  1   55.32  ? 122 ARG C CD  1 
ATOM   5486 N  NE  . ARG C 1 126 ? -46.097 -3.198  28.066  1   61.75  ? 122 ARG C NE  1 
ATOM   5487 C  CZ  . ARG C 1 126 ? -45.09  -2.794  27.257  1   61.45  ? 122 ARG C CZ  1 
ATOM   5488 N  NH1 . ARG C 1 126 ? -44.978 -1.542  26.842  1   56.12  ? 122 ARG C NH1 1 
ATOM   5489 N  NH2 . ARG C 1 126 ? -44.169 -3.65   26.863  1   62.33  ? 122 ARG C NH2 1 
ATOM   5490 N  N   . VAL C 1 127 ? -48.041 2.311   28.719  1   54.51  ? 123 VAL C N   1 
ATOM   5491 C  CA  . VAL C 1 127 ? -47.194 3.05    29.653  1   52.95  ? 123 VAL C CA  1 
ATOM   5492 C  C   . VAL C 1 127 ? -47.94  4.299   30.129  1   52.4   ? 123 VAL C C   1 
ATOM   5493 O  O   . VAL C 1 127 ? -48.306 5.151   29.326  1   52.54  ? 123 VAL C O   1 
ATOM   5494 C  CB  . VAL C 1 127 ? -45.835 3.431   29      1   50.79  ? 123 VAL C CB  1 
ATOM   5495 C  CG1 . VAL C 1 127 ? -45.086 4.567   29.714  1   42.03  ? 123 VAL C CG1 1 
ATOM   5496 C  CG2 . VAL C 1 127 ? -44.92  2.223   28.8    1   47.65  ? 123 VAL C CG2 1 
ATOM   5497 N  N   . LEU C 1 128 ? -48.147 4.395   31.446  1   52.94  ? 124 LEU C N   1 
ATOM   5498 C  CA  . LEU C 1 128 ? -48.524 5.631   32.126  1   52.14  ? 124 LEU C CA  1 
ATOM   5499 C  C   . LEU C 1 128 ? -47.26  6.431   32.417  1   49.64  ? 124 LEU C C   1 
ATOM   5500 O  O   . LEU C 1 128 ? -46.242 5.842   32.781  1   53.06  ? 124 LEU C O   1 
ATOM   5501 C  CB  . LEU C 1 128 ? -49.247 5.323   33.442  1   49.36  ? 124 LEU C CB  1 
ATOM   5502 C  CG  . LEU C 1 128 ? -50.529 4.487   33.363  1   48.92  ? 124 LEU C CG  1 
ATOM   5503 C  CD1 . LEU C 1 128 ? -51.089 4.317   34.776  1   48.99  ? 124 LEU C CD1 1 
ATOM   5504 C  CD2 . LEU C 1 128 ? -51.54  5.106   32.397  1   46.11  ? 124 LEU C CD2 1 
ATOM   5505 N  N   . HIS C 1 129 ? -47.346 7.764   32.286  1   48.13  ? 125 HIS C N   1 
ATOM   5506 C  CA  . HIS C 1 129 ? -46.231 8.639   32.616  1   45.79  ? 125 HIS C CA  1 
ATOM   5507 C  C   . HIS C 1 129 ? -46.251 8.991   34.106  1   50.07  ? 125 HIS C C   1 
ATOM   5508 O  O   . HIS C 1 129 ? -45.26  8.799   34.814  1   50.56  ? 125 HIS C O   1 
ATOM   5509 C  CB  . HIS C 1 129 ? -46.263 9.908   31.772  1   44.71  ? 125 HIS C CB  1 
ATOM   5510 C  CG  . HIS C 1 129 ? -45.04  10.751  31.911  1   52.36  ? 125 HIS C CG  1 
ATOM   5511 N  ND1 . HIS C 1 129 ? -44.843 11.628  32.967  1   49.86  ? 125 HIS C ND1 1 
ATOM   5512 C  CD2 . HIS C 1 129 ? -43.952 10.855  31.118  1   51.69  ? 125 HIS C CD2 1 
ATOM   5513 C  CE1 . HIS C 1 129 ? -43.68  12.246  32.806  1   51.15  ? 125 HIS C CE1 1 
ATOM   5514 N  NE2 . HIS C 1 129 ? -43.118 11.795  31.693  1   56.51  ? 125 HIS C NE2 1 
ATOM   5515 N  N   . ARG C 1 130 ? -47.375 9.56    34.562  1   48.76  ? 126 ARG C N   1 
ATOM   5516 C  CA  . ARG C 1 130 ? -47.633 9.788   35.973  1   49.85  ? 126 ARG C CA  1 
ATOM   5517 C  C   . ARG C 1 130 ? -46.783 10.922  36.561  1   51.35  ? 126 ARG C C   1 
ATOM   5518 O  O   . ARG C 1 130 ? -46.75  11.092  37.772  1   48.38  ? 126 ARG C O   1 
ATOM   5519 C  CB  . ARG C 1 130 ? -47.408 8.499   36.771  1   46.45  ? 126 ARG C CB  1 
ATOM   5520 C  CG  . ARG C 1 130 ? -48.329 7.366   36.355  1   47.12  ? 126 ARG C CG  1 
ATOM   5521 C  CD  . ARG C 1 130 ? -48.281 6.236   37.375  1   48.5   ? 126 ARG C CD  1 
ATOM   5522 N  NE  . ARG C 1 130 ? -46.941 5.697   37.654  1   48.78  ? 126 ARG C NE  1 
ATOM   5523 C  CZ  . ARG C 1 130 ? -46.714 4.735   38.545  1   52.52  ? 126 ARG C CZ  1 
ATOM   5524 N  NH1 . ARG C 1 130 ? -47.735 4.156   39.169  1   51.29  ? 126 ARG C NH1 1 
ATOM   5525 N  NH2 . ARG C 1 130 ? -45.47  4.337   38.787  1   49.77  ? 126 ARG C NH2 1 
ATOM   5526 N  N   . ASP C 1 131 ? -46.12  11.73   35.729  1   50.92  ? 127 ASP C N   1 
ATOM   5527 C  CA  . ASP C 1 131 ? -45.439 12.897  36.262  1   51.36  ? 127 ASP C CA  1 
ATOM   5528 C  C   . ASP C 1 131 ? -45.375 13.997  35.204  1   50.06  ? 127 ASP C C   1 
ATOM   5529 O  O   . ASP C 1 131 ? -44.34  14.631  35.004  1   50.24  ? 127 ASP C O   1 
ATOM   5530 C  CB  . ASP C 1 131 ? -44.063 12.57   36.818  1   51.21  ? 127 ASP C CB  1 
ATOM   5531 C  CG  . ASP C 1 131 ? -43.522 13.612  37.798  1   57.95  ? 127 ASP C CG  1 
ATOM   5532 O  OD1 . ASP C 1 131 ? -44.323 14.451  38.295  1   57.26  ? 127 ASP C OD1 1 
ATOM   5533 O  OD2 . ASP C 1 131 ? -42.3   13.605  38.034  1   60.52  ? 127 ASP C OD2 1 
ATOM   5534 N  N   . LEU C 1 132 ? -46.496 14.211  34.52   1   44.8   ? 128 LEU C N   1 
ATOM   5535 C  CA  . LEU C 1 132 ? -46.506 15.248  33.51   1   47.97  ? 128 LEU C CA  1 
ATOM   5536 C  C   . LEU C 1 132 ? -46.656 16.58   34.226  1   48.95  ? 128 LEU C C   1 
ATOM   5537 O  O   . LEU C 1 132 ? -47.609 16.787  34.953  1   56.45  ? 128 LEU C O   1 
ATOM   5538 C  CB  . LEU C 1 132 ? -47.604 14.971  32.482  1   49.28  ? 128 LEU C CB  1 
ATOM   5539 C  CG  . LEU C 1 132 ? -47.377 13.725  31.611  1   47.52  ? 128 LEU C CG  1 
ATOM   5540 C  CD1 . LEU C 1 132 ? -48.678 13.215  31.049  1   44.84  ? 128 LEU C CD1 1 
ATOM   5541 C  CD2 . LEU C 1 132 ? -46.396 13.998  30.491  1   46.6   ? 128 LEU C CD2 1 
ATOM   5542 N  N   . LYS C 1 133 ? -45.635 17.415  34.094  1   46.87  ? 129 LYS C N   1 
ATOM   5543 C  CA  . LYS C 1 133 ? -45.625 18.785  34.561  1   47.27  ? 129 LYS C CA  1 
ATOM   5544 C  C   . LYS C 1 133 ? -44.663 19.576  33.671  1   49.86  ? 129 LYS C C   1 
ATOM   5545 O  O   . LYS C 1 133 ? -43.836 18.999  32.966  1   46.52  ? 129 LYS C O   1 
ATOM   5546 C  CB  . LYS C 1 133 ? -45.195 18.76   36.028  1   48.01  ? 129 LYS C CB  1 
ATOM   5547 C  CG  . LYS C 1 133 ? -43.881 18.041  36.308  1   51.74  ? 129 LYS C CG  1 
ATOM   5548 C  CD  . LYS C 1 133 ? -43.402 18.246  37.743  1   51.95  ? 129 LYS C CD  1 
ATOM   5549 C  CE  . LYS C 1 133 ? -42.218 17.383  37.989  1   58.32  ? 129 LYS C CE  1 
ATOM   5550 N  NZ  . LYS C 1 133 ? -41.377 17.856  39.086  1   69.4   ? 129 LYS C NZ  1 
ATOM   5551 N  N   . PRO C 1 134 ? -44.715 20.927  33.655  1   53.95  ? 130 PRO C N   1 
ATOM   5552 C  CA  . PRO C 1 134 ? -43.916 21.701  32.698  1   53.62  ? 130 PRO C CA  1 
ATOM   5553 C  C   . PRO C 1 134 ? -42.413 21.416  32.709  1   52.66  ? 130 PRO C C   1 
ATOM   5554 O  O   . PRO C 1 134 ? -41.76  21.509  31.67   1   49.73  ? 130 PRO C O   1 
ATOM   5555 C  CB  . PRO C 1 134 ? -44.211 23.149  33.097  1   55.13  ? 130 PRO C CB  1 
ATOM   5556 C  CG  . PRO C 1 134 ? -45.543 23.089  33.802  1   53.48  ? 130 PRO C CG  1 
ATOM   5557 C  CD  . PRO C 1 134 ? -45.55  21.766  34.532  1   52.79  ? 130 PRO C CD  1 
ATOM   5558 N  N   . GLN C 1 135 ? -41.881 21.091  33.901  1   55.57  ? 131 GLN C N   1 
ATOM   5559 C  CA  . GLN C 1 135 ? -40.458 20.875  34.142  1   52.49  ? 131 GLN C CA  1 
ATOM   5560 C  C   . GLN C 1 135 ? -39.975 19.588  33.479  1   51.38  ? 131 GLN C C   1 
ATOM   5561 O  O   . GLN C 1 135 ? -38.77  19.433  33.343  1   53.85  ? 131 GLN C O   1 
ATOM   5562 C  CB  . GLN C 1 135 ? -40.166 20.676  35.626  1   50.97  ? 131 GLN C CB  1 
ATOM   5563 C  CG  . GLN C 1 135 ? -40.41  21.899  36.505  1   61.7   ? 131 GLN C CG  1 
ATOM   5564 C  CD  . GLN C 1 135 ? -41.84  22.144  36.968  1   66.5   ? 131 GLN C CD  1 
ATOM   5565 O  OE1 . GLN C 1 135 ? -42.817 21.489  36.579  1   62.54  ? 131 GLN C OE1 1 
ATOM   5566 N  NE2 . GLN C 1 135 ? -41.978 23.17   37.794  1   67.11  ? 131 GLN C NE2 1 
ATOM   5567 N  N   . ASN C 1 136 ? -40.91  18.681  33.116  1   47.55  ? 132 ASN C N   1 
ATOM   5568 C  CA  . ASN C 1 136 ? -40.65  17.368  32.543  1   44.87  ? 132 ASN C CA  1 
ATOM   5569 C  C   . ASN C 1 136 ? -40.987 17.343  31.049  1   47.78  ? 132 ASN C C   1 
ATOM   5570 O  O   . ASN C 1 136 ? -40.994 16.268  30.428  1   51.35  ? 132 ASN C O   1 
ATOM   5571 C  CB  . ASN C 1 136 ? -41.393 16.255  33.279  1   44.83  ? 132 ASN C CB  1 
ATOM   5572 C  CG  . ASN C 1 136 ? -40.888 15.999  34.688  1   50.68  ? 132 ASN C CG  1 
ATOM   5573 O  OD1 . ASN C 1 136 ? -39.797 16.469  35.061  1   47.97  ? 132 ASN C OD1 1 
ATOM   5574 N  ND2 . ASN C 1 136 ? -41.663 15.259  35.486  1   44.67  ? 132 ASN C ND2 1 
ATOM   5575 N  N   . LEU C 1 137 ? -41.254 18.523  30.47   1   43.03  ? 133 LEU C N   1 
ATOM   5576 C  CA  . LEU C 1 137 ? -41.471 18.665  29.035  1   44.65  ? 133 LEU C CA  1 
ATOM   5577 C  C   . LEU C 1 137 ? -40.344 19.52   28.453  1   48.45  ? 133 LEU C C   1 
ATOM   5578 O  O   . LEU C 1 137 ? -40.055 20.604  28.975  1   45.44  ? 133 LEU C O   1 
ATOM   5579 C  CB  . LEU C 1 137 ? -42.844 19.279  28.781  1   43.61  ? 133 LEU C CB  1 
ATOM   5580 C  CG  . LEU C 1 137 ? -44.026 18.606  29.489  1   46.12  ? 133 LEU C CG  1 
ATOM   5581 C  CD1 . LEU C 1 137 ? -45.311 19.38   29.259  1   48.82  ? 133 LEU C CD1 1 
ATOM   5582 C  CD2 . LEU C 1 137 ? -44.214 17.162  29.053  1   42.81  ? 133 LEU C CD2 1 
ATOM   5583 N  N   . LEU C 1 138 ? -39.704 19.01   27.383  1   50.15  ? 134 LEU C N   1 
ATOM   5584 C  CA  . LEU C 1 138 ? -38.518 19.614  26.781  1   52.14  ? 134 LEU C CA  1 
ATOM   5585 C  C   . LEU C 1 138 ? -38.854 20.185  25.4    1   53.33  ? 134 LEU C C   1 
ATOM   5586 O  O   . LEU C 1 138 ? -39.476 19.515  24.577  1   57.92  ? 134 LEU C O   1 
ATOM   5587 C  CB  . LEU C 1 138 ? -37.42  18.553  26.683  1   52.46  ? 134 LEU C CB  1 
ATOM   5588 C  CG  . LEU C 1 138 ? -37.09  17.8    27.983  1   56.27  ? 134 LEU C CG  1 
ATOM   5589 C  CD1 . LEU C 1 138 ? -35.961 16.794  27.738  1   54.93  ? 134 LEU C CD1 1 
ATOM   5590 C  CD2 . LEU C 1 138 ? -36.755 18.699  29.185  1   47.74  ? 134 LEU C CD2 1 
ATOM   5591 N  N   . ILE C 1 139 ? -38.44  21.432  25.157  1   48.49  ? 135 ILE C N   1 
ATOM   5592 C  CA  . ILE C 1 139 ? -38.606 22.07   23.861  1   52.14  ? 135 ILE C CA  1 
ATOM   5593 C  C   . ILE C 1 139 ? -37.222 22.271  23.24   1   55.01  ? 135 ILE C C   1 
ATOM   5594 O  O   . ILE C 1 139 ? -36.27  22.489  23.982  1   56.07  ? 135 ILE C O   1 
ATOM   5595 C  CB  . ILE C 1 139 ? -39.333 23.416  24.052  1   50.89  ? 135 ILE C CB  1 
ATOM   5596 C  CG1 . ILE C 1 139 ? -38.529 24.392  24.928  1   51.27  ? 135 ILE C CG1 1 
ATOM   5597 C  CG2 . ILE C 1 139 ? -40.739 23.186  24.596  1   49.62  ? 135 ILE C CG2 1 
ATOM   5598 C  CD1 . ILE C 1 139 ? -38.986 25.836  24.841  1   56.97  ? 135 ILE C CD1 1 
ATOM   5599 N  N   . ASN C 1 140 ? -37.115 22.203  21.899  1   56.84  ? 136 ASN C N   1 
ATOM   5600 C  CA  . ASN C 1 140 ? -35.948 22.713  21.175  1   63.03  ? 136 ASN C CA  1 
ATOM   5601 C  C   . ASN C 1 140 ? -36.286 24.03   20.457  1   67.22  ? 136 ASN C C   1 
ATOM   5602 O  O   . ASN C 1 140 ? -37.388 24.579  20.629  1   75.66  ? 136 ASN C O   1 
ATOM   5603 C  CB  . ASN C 1 140 ? -35.32  21.686  20.233  1   62.46  ? 136 ASN C CB  1 
ATOM   5604 C  CG  . ASN C 1 140 ? -36.262 21.191  19.15   1   63.24  ? 136 ASN C CG  1 
ATOM   5605 O  OD1 . ASN C 1 140 ? -37.173 21.904  18.715  1   56.67  ? 136 ASN C OD1 1 
ATOM   5606 N  ND2 . ASN C 1 140 ? -36.104 19.942  18.742  1   65.39  ? 136 ASN C ND2 1 
ATOM   5607 N  N   . THR C 1 141 ? -35.323 24.522  19.656  1   66.36  ? 137 THR C N   1 
ATOM   5608 C  CA  . THR C 1 141 ? -35.39  25.828  19.002  1   73.49  ? 137 THR C CA  1 
ATOM   5609 C  C   . THR C 1 141 ? -36.189 25.785  17.697  1   73.39  ? 137 THR C C   1 
ATOM   5610 O  O   . THR C 1 141 ? -36.448 26.831  17.108  1   82.82  ? 137 THR C O   1 
ATOM   5611 C  CB  . THR C 1 141 ? -33.996 26.408  18.731  1   71.34  ? 137 THR C CB  1 
ATOM   5612 O  OG1 . THR C 1 141 ? -33.391 25.647  17.695  1   75.41  ? 137 THR C OG1 1 
ATOM   5613 C  CG2 . THR C 1 141 ? -33.068 26.382  19.927  1   69.99  ? 137 THR C CG2 1 
ATOM   5614 N  N   . GLU C 1 142 ? -36.552 24.583  17.236  1   72.54  ? 138 GLU C N   1 
ATOM   5615 C  CA  . GLU C 1 142 ? -37.25  24.399  15.971  1   76.36  ? 138 GLU C CA  1 
ATOM   5616 C  C   . GLU C 1 142 ? -38.722 24.034  16.179  1   77.05  ? 138 GLU C C   1 
ATOM   5617 O  O   . GLU C 1 142 ? -39.359 23.534  15.249  1   82.63  ? 138 GLU C O   1 
ATOM   5618 C  CB  . GLU C 1 142 ? -36.554 23.306  15.157  1   80.78  ? 138 GLU C CB  1 
ATOM   5619 C  CG  . GLU C 1 142 ? -35.055 23.545  14.998  1   92.06  ? 138 GLU C CG  1 
ATOM   5620 C  CD  . GLU C 1 142 ? -34.534 23.341  13.586  1   111.75 ? 138 GLU C CD  1 
ATOM   5621 O  OE1 . GLU C 1 142 ? -34.591 22.179  13.108  1   121.49 ? 138 GLU C OE1 1 
ATOM   5622 O  OE2 . GLU C 1 142 ? -34.087 24.346  12.965  1   109.11 ? 138 GLU C OE2 1 
ATOM   5623 N  N   . GLY C 1 143 ? -39.234 24.235  17.403  1   70.72  ? 139 GLY C N   1 
ATOM   5624 C  CA  . GLY C 1 143 ? -40.658 24.179  17.699  1   66.14  ? 139 GLY C CA  1 
ATOM   5625 C  C   . GLY C 1 143 ? -41.171 22.783  18.044  1   66.95  ? 139 GLY C C   1 
ATOM   5626 O  O   . GLY C 1 143 ? -42.389 22.572  18.043  1   65.38  ? 139 GLY C O   1 
ATOM   5627 N  N   . ALA C 1 144 ? -40.25  21.863  18.387  1   64.69  ? 140 ALA C N   1 
ATOM   5628 C  CA  . ALA C 1 144 ? -40.62  20.563  18.937  1   64.08  ? 140 ALA C CA  1 
ATOM   5629 C  C   . ALA C 1 144 ? -40.768 20.648  20.461  1   63.27  ? 140 ALA C C   1 
ATOM   5630 O  O   . ALA C 1 144 ? -40.072 21.442  21.102  1   62.03  ? 140 ALA C O   1 
ATOM   5631 C  CB  . ALA C 1 144 ? -39.583 19.53   18.554  1   61.69  ? 140 ALA C CB  1 
ATOM   5632 N  N   . ILE C 1 145 ? -41.693 19.836  21.013  1   58.65  ? 141 ILE C N   1 
ATOM   5633 C  CA  . ILE C 1 145 ? -41.773 19.534  22.445  1   61.31  ? 141 ILE C CA  1 
ATOM   5634 C  C   . ILE C 1 145 ? -41.814 18.015  22.661  1   58.28  ? 141 ILE C C   1 
ATOM   5635 O  O   . ILE C 1 145 ? -42.389 17.296  21.854  1   57.81  ? 141 ILE C O   1 
ATOM   5636 C  CB  . ILE C 1 145 ? -42.967 20.244  23.123  1   60.03  ? 141 ILE C CB  1 
ATOM   5637 C  CG1 . ILE C 1 145 ? -42.902 20.165  24.644  1   54.75  ? 141 ILE C CG1 1 
ATOM   5638 C  CG2 . ILE C 1 145 ? -44.315 19.736  22.603  1   58.86  ? 141 ILE C CG2 1 
ATOM   5639 C  CD1 . ILE C 1 145 ? -43.839 21.125  25.363  1   52.79  ? 141 ILE C CD1 1 
ATOM   5640 N  N   . LYS C 1 146 ? -41.226 17.532  23.764  1   58.62  ? 142 LYS C N   1 
ATOM   5641 C  CA  . LYS C 1 146 ? -41.126 16.102  24.043  1   57.43  ? 142 LYS C CA  1 
ATOM   5642 C  C   . LYS C 1 146 ? -41.338 15.824  25.53   1   51.88  ? 142 LYS C C   1 
ATOM   5643 O  O   . LYS C 1 146 ? -40.883 16.6    26.374  1   50.69  ? 142 LYS C O   1 
ATOM   5644 C  CB  . LYS C 1 146 ? -39.761 15.535  23.641  1   53.75  ? 142 LYS C CB  1 
ATOM   5645 C  CG  . LYS C 1 146 ? -39.411 15.766  22.204  1   54.03  ? 142 LYS C CG  1 
ATOM   5646 C  CD  . LYS C 1 146 ? -38.144 15.09   21.718  1   56.33  ? 142 LYS C CD  1 
ATOM   5647 C  CE  . LYS C 1 146 ? -37.691 15.656  20.378  1   58.04  ? 142 LYS C CE  1 
ATOM   5648 N  NZ  . LYS C 1 146 ? -36.691 14.798  19.725  1   53.67  ? 142 LYS C NZ  1 
ATOM   5649 N  N   . LEU C 1 147 ? -42.043 14.718  25.813  1   46.56  ? 143 LEU C N   1 
ATOM   5650 C  CA  . LEU C 1 147 ? -42.224 14.193  27.156  1   47.4   ? 143 LEU C CA  1 
ATOM   5651 C  C   . LEU C 1 147 ? -40.864 13.663  27.614  1   50.2   ? 143 LEU C C   1 
ATOM   5652 O  O   . LEU C 1 147 ? -40.191 12.96   26.871  1   56.39  ? 143 LEU C O   1 
ATOM   5653 C  CB  . LEU C 1 147 ? -43.254 13.061  27.21   1   45.83  ? 143 LEU C CB  1 
ATOM   5654 C  CG  . LEU C 1 147 ? -44.545 13.19   26.399  1   51.95  ? 143 LEU C CG  1 
ATOM   5655 C  CD1 . LEU C 1 147 ? -45.472 12.023  26.692  1   52.39  ? 143 LEU C CD1 1 
ATOM   5656 C  CD2 . LEU C 1 147 ? -45.279 14.475  26.687  1   54.28  ? 143 LEU C CD2 1 
ATOM   5657 N  N   . ALA C 1 148 ? -40.451 14.013  28.826  1   47.28  ? 144 ALA C N   1 
ATOM   5658 C  CA  . ALA C 1 148 ? -39.203 13.517  29.386  1   51.07  ? 144 ALA C CA  1 
ATOM   5659 C  C   . ALA C 1 148 ? -39.434 13.06   30.837  1   51.28  ? 144 ALA C C   1 
ATOM   5660 O  O   . ALA C 1 148 ? -40.578 13.012  31.275  1   51.54  ? 144 ALA C O   1 
ATOM   5661 C  CB  . ALA C 1 148 ? -38.176 14.618  29.267  1   47     ? 144 ALA C CB  1 
ATOM   5662 N  N   . ASP C 1 149 ? -38.366 12.697  31.563  1   49.17  ? 145 ASP C N   1 
ATOM   5663 C  CA  . ASP C 1 149 ? -38.402 12.16   32.923  1   56.35  ? 145 ASP C CA  1 
ATOM   5664 C  C   . ASP C 1 149 ? -39.413 11.017  33.109  1   54.38  ? 145 ASP C C   1 
ATOM   5665 O  O   . ASP C 1 149 ? -40.478 11.21   33.698  1   54.4   ? 145 ASP C O   1 
ATOM   5666 C  CB  . ASP C 1 149 ? -38.485 13.256  33.978  1   59.56  ? 145 ASP C CB  1 
ATOM   5667 C  CG  . ASP C 1 149 ? -37.908 12.849  35.33   1   76.21  ? 145 ASP C CG  1 
ATOM   5668 O  OD1 . ASP C 1 149 ? -37.729 11.617  35.554  1   68.83  ? 145 ASP C OD1 1 
ATOM   5669 O  OD2 . ASP C 1 149 ? -37.594 13.766  36.127  1   82.11  ? 145 ASP C OD2 1 
ATOM   5670 N  N   . PHE C 1 150 ? -39.054 9.809   32.656  1   48.77  ? 146 PHE C N   1 
ATOM   5671 C  CA  . PHE C 1 150 ? -39.915 8.638   32.772  1   48.88  ? 146 PHE C CA  1 
ATOM   5672 C  C   . PHE C 1 150 ? -39.582 7.802   34.017  1   53.62  ? 146 PHE C C   1 
ATOM   5673 O  O   . PHE C 1 150 ? -39.888 6.609   34.061  1   58.43  ? 146 PHE C O   1 
ATOM   5674 C  CB  . PHE C 1 150 ? -39.825 7.794   31.493  1   47.7   ? 146 PHE C CB  1 
ATOM   5675 C  CG  . PHE C 1 150 ? -40.657 8.32    30.335  1   45.62  ? 146 PHE C CG  1 
ATOM   5676 C  CD1 . PHE C 1 150 ? -40.286 9.485   29.655  1   43.21  ? 146 PHE C CD1 1 
ATOM   5677 C  CD2 . PHE C 1 150 ? -41.832 7.665   29.974  1   43.1   ? 146 PHE C CD2 1 
ATOM   5678 C  CE1 . PHE C 1 150 ? -41.07  9.98    28.623  1   43.76  ? 146 PHE C CE1 1 
ATOM   5679 C  CE2 . PHE C 1 150 ? -42.612 8.154   28.938  1   44.42  ? 146 PHE C CE2 1 
ATOM   5680 C  CZ  . PHE C 1 150 ? -42.22  9.302   28.254  1   45.14  ? 146 PHE C CZ  1 
ATOM   5681 N  N   . GLY C 1 151 ? -38.974 8.429   35.037  1   55.33  ? 147 GLY C N   1 
ATOM   5682 C  CA  . GLY C 1 151 ? -38.587 7.746   36.263  1   59.87  ? 147 GLY C CA  1 
ATOM   5683 C  C   . GLY C 1 151 ? -39.771 7.347   37.143  1   61.22  ? 147 GLY C C   1 
ATOM   5684 O  O   . GLY C 1 151 ? -39.602 6.501   38.012  1   71.32  ? 147 GLY C O   1 
ATOM   5685 N  N   . LEU C 1 152 ? -40.948 7.959   36.931  1   62.19  ? 148 LEU C N   1 
ATOM   5686 C  CA  . LEU C 1 152 ? -42.148 7.584   37.662  1   59.84  ? 148 LEU C CA  1 
ATOM   5687 C  C   . LEU C 1 152 ? -43.129 6.79    36.813  1   57.93  ? 148 LEU C C   1 
ATOM   5688 O  O   . LEU C 1 152 ? -44.208 6.455   37.307  1   66.96  ? 148 LEU C O   1 
ATOM   5689 C  CB  . LEU C 1 152 ? -42.793 8.846   38.206  1   61.16  ? 148 LEU C CB  1 
ATOM   5690 C  CG  . LEU C 1 152 ? -41.915 9.542   39.241  1   70.54  ? 148 LEU C CG  1 
ATOM   5691 C  CD1 . LEU C 1 152 ? -42.63  10.822  39.548  1   85.59  ? 148 LEU C CD1 1 
ATOM   5692 C  CD2 . LEU C 1 152 ? -41.755 8.639   40.434  1   72.71  ? 148 LEU C CD2 1 
ATOM   5693 N  N   . ALA C 1 153 ? -42.753 6.525   35.552  1   53.14  ? 149 ALA C N   1 
ATOM   5694 C  CA  . ALA C 1 153 ? -43.596 5.857   34.568  1   50.81  ? 149 ALA C CA  1 
ATOM   5695 C  C   . ALA C 1 153 ? -43.852 4.409   34.989  1   52.66  ? 149 ALA C C   1 
ATOM   5696 O  O   . ALA C 1 153 ? -43.116 3.854   35.796  1   50.69  ? 149 ALA C O   1 
ATOM   5697 C  CB  . ALA C 1 153 ? -42.941 5.92    33.2    1   48.05  ? 149 ALA C CB  1 
ATOM   5698 N  N   . ARG C 1 154 ? -44.935 3.832   34.465  1   52.05  ? 150 ARG C N   1 
ATOM   5699 C  CA  . ARG C 1 154 ? -45.288 2.432   34.798  1   55.32  ? 150 ARG C CA  1 
ATOM   5700 C  C   . ARG C 1 154 ? -45.959 1.728   33.617  1   55.13  ? 150 ARG C C   1 
ATOM   5701 O  O   . ARG C 1 154 ? -46.825 2.34    32.978  1   59.57  ? 150 ARG C O   1 
ATOM   5702 C  CB  . ARG C 1 154 ? -46.273 2.344   35.959  1   54.7   ? 150 ARG C CB  1 
ATOM   5703 C  CG  . ARG C 1 154 ? -45.844 1.319   36.993  1   60.77  ? 150 ARG C CG  1 
ATOM   5704 C  CD  . ARG C 1 154 ? -47.069 0.903   37.761  1   65.02  ? 150 ARG C CD  1 
ATOM   5705 N  NE  . ARG C 1 154 ? -47.205 -0.553  37.761  1   62.13  ? 150 ARG C NE  1 
ATOM   5706 C  CZ  . ARG C 1 154 ? -46.599 -1.351  38.615  1   59.39  ? 150 ARG C CZ  1 
ATOM   5707 N  NH1 . ARG C 1 154 ? -46.384 -0.961  39.857  1   58.53  ? 150 ARG C NH1 1 
ATOM   5708 N  NH2 . ARG C 1 154 ? -46.218 -2.544  38.216  1   54.7   ? 150 ARG C NH2 1 
ATOM   5709 N  N   . ALA C 1 155 ? -45.568 0.484   33.354  1   52.7   ? 151 ALA C N   1 
ATOM   5710 C  CA  . ALA C 1 155 ? -46.199 -0.304  32.316  1   51.06  ? 151 ALA C CA  1 
ATOM   5711 C  C   . ALA C 1 155 ? -47.43  -0.965  32.927  1   56.33  ? 151 ALA C C   1 
ATOM   5712 O  O   . ALA C 1 155 ? -47.322 -1.635  33.951  1   62.96  ? 151 ALA C O   1 
ATOM   5713 C  CB  . ALA C 1 155 ? -45.208 -1.317  31.786  1   45.46  ? 151 ALA C CB  1 
ATOM   5714 N  N   . PHE C 1 156 ? -48.6   -0.762  32.308  1   54.49  ? 152 PHE C N   1 
ATOM   5715 C  CA  . PHE C 1 156 ? -49.852 -1.214  32.904  1   56.1   ? 152 PHE C CA  1 
ATOM   5716 C  C   . PHE C 1 156 ? -50.408 -2.448  32.191  1   62.83  ? 152 PHE C C   1 
ATOM   5717 O  O   . PHE C 1 156 ? -50.102 -2.699  31.025  1   65.05  ? 152 PHE C O   1 
ATOM   5718 C  CB  . PHE C 1 156 ? -50.876 -0.08   33.022  1   51.23  ? 152 PHE C CB  1 
ATOM   5719 C  CG  . PHE C 1 156 ? -51.352 0.563   31.736  1   50.75  ? 152 PHE C CG  1 
ATOM   5720 C  CD1 . PHE C 1 156 ? -52.502 0.105   31.098  1   50.05  ? 152 PHE C CD1 1 
ATOM   5721 C  CD2 . PHE C 1 156 ? -50.692 1.676   31.216  1   50.74  ? 152 PHE C CD2 1 
ATOM   5722 C  CE1 . PHE C 1 156 ? -52.956 0.715   29.932  1   51.4   ? 152 PHE C CE1 1 
ATOM   5723 C  CE2 . PHE C 1 156 ? -51.165 2.291   30.059  1   53.51  ? 152 PHE C CE2 1 
ATOM   5724 C  CZ  . PHE C 1 156 ? -52.298 1.814   29.413  1   50.03  ? 152 PHE C CZ  1 
ATOM   5725 N  N   . GLY C 1 157 ? -51.224 -3.218  32.926  1   64.9   ? 153 GLY C N   1 
ATOM   5726 C  CA  . GLY C 1 157 ? -52.05  -4.271  32.353  1   67.17  ? 153 GLY C CA  1 
ATOM   5727 C  C   . GLY C 1 157 ? -53.441 -3.742  31.994  1   68.77  ? 153 GLY C C   1 
ATOM   5728 O  O   . GLY C 1 157 ? -53.794 -2.628  32.391  1   71.02  ? 153 GLY C O   1 
ATOM   5729 N  N   . VAL C 1 158 ? -54.207 -4.539  31.232  1   65.56  ? 154 VAL C N   1 
ATOM   5730 C  CA  . VAL C 1 158 ? -55.577 -4.221  30.855  1   68.9   ? 154 VAL C CA  1 
ATOM   5731 C  C   . VAL C 1 158 ? -56.498 -5.337  31.365  1   73.22  ? 154 VAL C C   1 
ATOM   5732 O  O   . VAL C 1 158 ? -56.352 -6.484  30.937  1   75.25  ? 154 VAL C O   1 
ATOM   5733 C  CB  . VAL C 1 158 ? -55.7   -4.054  29.324  1   68.58  ? 154 VAL C CB  1 
ATOM   5734 C  CG1 . VAL C 1 158 ? -57.121 -3.698  28.903  1   72.66  ? 154 VAL C CG1 1 
ATOM   5735 C  CG2 . VAL C 1 158 ? -54.697 -3.058  28.749  1   63.49  ? 154 VAL C CG2 1 
ATOM   5736 N  N   . PRO C 1 159 ? -57.449 -5.093  32.311  1   75.69  ? 155 PRO C N   1 
ATOM   5737 C  CA  . PRO C 1 159 ? -57.658 -3.781  32.945  1   73.25  ? 155 PRO C CA  1 
ATOM   5738 C  C   . PRO C 1 159 ? -56.557 -3.43   33.937  1   73.13  ? 155 PRO C C   1 
ATOM   5739 O  O   . PRO C 1 159 ? -55.842 -4.32   34.413  1   73.01  ? 155 PRO C O   1 
ATOM   5740 C  CB  . PRO C 1 159 ? -58.984 -3.973  33.709  1   73.92  ? 155 PRO C CB  1 
ATOM   5741 C  CG  . PRO C 1 159 ? -58.994 -5.455  34.066  1   74.52  ? 155 PRO C CG  1 
ATOM   5742 C  CD  . PRO C 1 159 ? -58.345 -6.131  32.867  1   72.24  ? 155 PRO C CD  1 
ATOM   5743 N  N   . VAL C 1 160 ? -56.468 -2.135  34.274  1   70.89  ? 156 VAL C N   1 
ATOM   5744 C  CA  . VAL C 1 160 ? -55.465 -1.672  35.217  1   65.69  ? 156 VAL C CA  1 
ATOM   5745 C  C   . VAL C 1 160 ? -55.741 -2.343  36.55   1   66.9   ? 156 VAL C C   1 
ATOM   5746 O  O   . VAL C 1 160 ? -56.882 -2.705  36.828  1   73.06  ? 156 VAL C O   1 
ATOM   5747 C  CB  . VAL C 1 160 ? -55.44  -0.146  35.39   1   62.72  ? 156 VAL C CB  1 
ATOM   5748 C  CG1 . VAL C 1 160 ? -55.296 0.578   34.055  1   64.43  ? 156 VAL C CG1 1 
ATOM   5749 C  CG2 . VAL C 1 160 ? -56.662 0.337   36.142  1   63.1   ? 156 VAL C CG2 1 
ATOM   5750 N  N   . ARG C 1 161 ? -54.677 -2.492  37.34   1   66.13  ? 157 ARG C N   1 
ATOM   5751 C  CA  . ARG C 1 161 ? -54.764 -2.917  38.727  1   71.08  ? 157 ARG C CA  1 
ATOM   5752 C  C   . ARG C 1 161 ? -54.316 -1.75   39.625  1   67.73  ? 157 ARG C C   1 
ATOM   5753 O  O   . ARG C 1 161 ? -53.92  -0.703  39.109  1   65.12  ? 157 ARG C O   1 
ATOM   5754 C  CB  . ARG C 1 161 ? -53.926 -4.195  38.867  1   72.16  ? 157 ARG C CB  1 
ATOM   5755 C  CG  . ARG C 1 161 ? -52.46  -3.9    39.144  1   79.96  ? 157 ARG C CG  1 
ATOM   5756 C  CD  . ARG C 1 161 ? -51.843 -5.087  39.868  1   89.81  ? 157 ARG C CD  1 
ATOM   5757 N  NE  . ARG C 1 161 ? -50.521 -4.699  40.375  1   97.42  ? 157 ARG C NE  1 
ATOM   5758 C  CZ  . ARG C 1 161 ? -49.378 -5.071  39.834  1   92.01  ? 157 ARG C CZ  1 
ATOM   5759 N  NH1 . ARG C 1 161 ? -49.377 -5.983  38.872  1   88.23  ? 157 ARG C NH1 1 
ATOM   5760 N  NH2 . ARG C 1 161 ? -48.257 -4.531  40.278  1   83.45  ? 157 ARG C NH2 1 
ATOM   5761 N  N   . THR C 1 162 ? -54.367 -1.927  40.959  1   63.53  ? 158 THR C N   1 
ATOM   5762 C  CA  . THR C 1 162 ? -53.864 -0.93   41.9    1   62.84  ? 158 THR C CA  1 
ATOM   5763 C  C   . THR C 1 162 ? -52.354 -0.748  41.714  1   60.52  ? 158 THR C C   1 
ATOM   5764 O  O   . THR C 1 162 ? -51.608 -1.731  41.844  1   59.25  ? 158 THR C O   1 
ATOM   5765 C  CB  . THR C 1 162 ? -54.216 -1.34   43.334  1   64.7   ? 158 THR C CB  1 
ATOM   5766 O  OG1 . THR C 1 162 ? -55.623 -1.167  43.411  1   69.15  ? 158 THR C OG1 1 
ATOM   5767 C  CG2 . THR C 1 162 ? -53.593 -0.467  44.413  1   60.06  ? 158 THR C CG2 1 
ATOM   5768 N  N   . TYR C 1 163 ? -51.95  0.515   41.439  1   53.41  ? 159 TYR C N   1 
ATOM   5769 C  CA  . TYR C 1 163 ? -50.568 0.964   41.347  1   51.78  ? 159 TYR C CA  1 
ATOM   5770 C  C   . TYR C 1 163 ? -50.271 1.915   42.502  1   53.8   ? 159 TYR C C   1 
ATOM   5771 O  O   . TYR C 1 163 ? -51.144 2.12    43.341  1   58.61  ? 159 TYR C O   1 
ATOM   5772 C  CB  . TYR C 1 163 ? -50.295 1.618   39.988  1   54.78  ? 159 TYR C CB  1 
ATOM   5773 C  CG  . TYR C 1 163 ? -50.645 0.726   38.808  1   57.35  ? 159 TYR C CG  1 
ATOM   5774 C  CD1 . TYR C 1 163 ? -50.261 -0.613  38.794  1   59.71  ? 159 TYR C CD1 1 
ATOM   5775 C  CD2 . TYR C 1 163 ? -51.4   1.206   37.744  1   55.24  ? 159 TYR C CD2 1 
ATOM   5776 C  CE1 . TYR C 1 163 ? -50.61  -1.45   37.75   1   61.59  ? 159 TYR C CE1 1 
ATOM   5777 C  CE2 . TYR C 1 163 ? -51.758 0.377   36.696  1   56.04  ? 159 TYR C CE2 1 
ATOM   5778 C  CZ  . TYR C 1 163 ? -51.355 -0.949  36.697  1   59.13  ? 159 TYR C CZ  1 
ATOM   5779 O  OH  . TYR C 1 163 ? -51.683 -1.796  35.679  1   62.86  ? 159 TYR C OH  1 
HETATM 5780 N  N   . TPO C 1 164 ? -49.053 2.494   42.528  1   56.5   ? 160 TPO C N   1 
HETATM 5781 C  CA  . TPO C 1 164 ? -48.576 3.382   43.589  1   59.43  ? 160 TPO C CA  1 
HETATM 5782 C  CB  . TPO C 1 164 ? -47.118 3.791   43.339  1   56.13  ? 160 TPO C CB  1 
HETATM 5783 C  CG2 . TPO C 1 164 ? -46.499 4.54    44.498  1   51.81  ? 160 TPO C CG2 1 
HETATM 5784 O  OG1 . TPO C 1 164 ? -46.34  2.556   43.132  1   58.63  ? 160 TPO C OG1 1 
HETATM 5785 P  P   . TPO C 1 164 ? -45.68  2.181   41.698  1   54.31  ? 160 TPO C P   1 
HETATM 5786 O  O1P . TPO C 1 164 ? -46.817 1.805   40.777  1   54.63  ? 160 TPO C O1P 1 
HETATM 5787 O  O2P . TPO C 1 164 ? -44.732 1.044   42.004  1   53.57  ? 160 TPO C O2P 1 
HETATM 5788 O  O3P . TPO C 1 164 ? -44.994 3.399   41.209  1   48.21  ? 160 TPO C O3P 1 
HETATM 5789 C  C   . TPO C 1 164 ? -49.441 4.644   43.669  1   64.32  ? 160 TPO C C   1 
HETATM 5790 O  O   . TPO C 1 164 ? -49.765 5.228   42.641  1   61.69  ? 160 TPO C O   1 
ATOM   5791 N  N   . HIS C 1 165 ? -49.822 5.051   44.889  1   67.9   ? 161 HIS C N   1 
ATOM   5792 C  CA  . HIS C 1 165 ? -50.7   6.193   45.094  1   75.19  ? 161 HIS C CA  1 
ATOM   5793 C  C   . HIS C 1 165 ? -49.939 7.519   45.031  1   76.64  ? 161 HIS C C   1 
ATOM   5794 O  O   . HIS C 1 165 ? -50.469 8.526   44.552  1   74.1   ? 161 HIS C O   1 
ATOM   5795 C  CB  . HIS C 1 165 ? -51.427 6.088   46.438  1   84.27  ? 161 HIS C CB  1 
ATOM   5796 C  CG  . HIS C 1 165 ? -52.265 7.296   46.732  1   102.71 ? 161 HIS C CG  1 
ATOM   5797 N  ND1 . HIS C 1 165 ? -51.88  8.321   47.581  1   98.84  ? 161 HIS C ND1 1 
ATOM   5798 C  CD2 . HIS C 1 165 ? -53.47  7.647   46.254  1   108.41 ? 161 HIS C CD2 1 
ATOM   5799 C  CE1 . HIS C 1 165 ? -52.826 9.248   47.618  1   102.62 ? 161 HIS C CE1 1 
ATOM   5800 N  NE2 . HIS C 1 165 ? -53.804 8.857   46.825  1   109.1  ? 161 HIS C NE2 1 
ATOM   5801 N  N   . GLU C 1 166 ? -48.698 7.523   45.524  1   83.16  ? 162 GLU C N   1 
ATOM   5802 C  CA  . GLU C 1 166 ? -47.92  8.75    45.632  1   86.26  ? 162 GLU C CA  1 
ATOM   5803 C  C   . GLU C 1 166 ? -47.325 9.05    44.254  1   83.48  ? 162 GLU C C   1 
ATOM   5804 O  O   . GLU C 1 166 ? -46.146 8.789   43.997  1   81.79  ? 162 GLU C O   1 
ATOM   5805 C  CB  . GLU C 1 166 ? -46.958 8.752   46.83   1   89.22  ? 162 GLU C CB  1 
ATOM   5806 C  CG  . GLU C 1 166 ? -46.728 7.377   47.465  1   105.51 ? 162 GLU C CG  1 
ATOM   5807 C  CD  . GLU C 1 166 ? -47.859 6.879   48.362  1   111.14 ? 162 GLU C CD  1 
ATOM   5808 O  OE1 . GLU C 1 166 ? -48.238 7.63    49.28   1   116.84 ? 162 GLU C OE1 1 
ATOM   5809 O  OE2 . GLU C 1 166 ? -48.377 5.761   48.17   1   108.29 ? 162 GLU C OE2 1 
ATOM   5810 N  N   . VAL C 1 167 ? -48.172 9.576   43.357  1   72.49  ? 163 VAL C N   1 
ATOM   5811 C  CA  . VAL C 1 167 ? -47.776 9.814   41.976  1   68.93  ? 163 VAL C CA  1 
ATOM   5812 C  C   . VAL C 1 167 ? -48.361 11.149  41.517  1   63.05  ? 163 VAL C C   1 
ATOM   5813 O  O   . VAL C 1 167 ? -49.464 11.514  41.931  1   62.62  ? 163 VAL C O   1 
ATOM   5814 C  CB  . VAL C 1 167 ? -48.15  8.683   40.991  1   64.18  ? 163 VAL C CB  1 
ATOM   5815 C  CG1 . VAL C 1 167 ? -47.49  7.376   41.364  1   55.15  ? 163 VAL C CG1 1 
ATOM   5816 C  CG2 . VAL C 1 167 ? -49.66  8.505   40.88   1   62.71  ? 163 VAL C CG2 1 
ATOM   5817 N  N   . VAL C 1 168 ? -47.601 11.833  40.645  1   57.31  ? 164 VAL C N   1 
ATOM   5818 C  CA  . VAL C 1 168 ? -47.948 13.124  40.061  1   60.31  ? 164 VAL C CA  1 
ATOM   5819 C  C   . VAL C 1 168 ? -47.707 14.207  41.119  1   59.93  ? 164 VAL C C   1 
ATOM   5820 O  O   . VAL C 1 168 ? -48.244 14.146  42.231  1   57.2   ? 164 VAL C O   1 
ATOM   5821 C  CB  . VAL C 1 168 ? -49.351 13.236  39.405  1   59.02  ? 164 VAL C CB  1 
ATOM   5822 C  CG1 . VAL C 1 168 ? -49.441 14.458  38.515  1   57.84  ? 164 VAL C CG1 1 
ATOM   5823 C  CG2 . VAL C 1 168 ? -49.744 12.011  38.573  1   59.17  ? 164 VAL C CG2 1 
ATOM   5824 N  N   . THR C 1 169 ? -46.871 15.196  40.779  1   62.25  ? 165 THR C N   1 
ATOM   5825 C  CA  . THR C 1 169 ? -46.734 16.399  41.593  1   65.94  ? 165 THR C CA  1 
ATOM   5826 C  C   . THR C 1 169 ? -48.136 16.946  41.902  1   62.27  ? 165 THR C C   1 
ATOM   5827 O  O   . THR C 1 169 ? -49     16.939  41.03   1   66.67  ? 165 THR C O   1 
ATOM   5828 C  CB  . THR C 1 169 ? -45.894 17.402  40.794  1   68.13  ? 165 THR C CB  1 
ATOM   5829 O  OG1 . THR C 1 169 ? -44.741 16.701  40.325  1   66.53  ? 165 THR C OG1 1 
ATOM   5830 C  CG2 . THR C 1 169 ? -45.576 18.656  41.597  1   65.42  ? 165 THR C CG2 1 
ATOM   5831 N  N   . LEU C 1 170 ? -48.349 17.465  43.116  1   57.44  ? 166 LEU C N   1 
ATOM   5832 C  CA  . LEU C 1 170 ? -49.657 17.864  43.621  1   56.11  ? 166 LEU C CA  1 
ATOM   5833 C  C   . LEU C 1 170 ? -50.495 18.681  42.63   1   57.31  ? 166 LEU C C   1 
ATOM   5834 O  O   . LEU C 1 170 ? -51.661 18.363  42.393  1   61.51  ? 166 LEU C O   1 
ATOM   5835 C  CB  . LEU C 1 170 ? -49.462 18.624  44.935  1   51.46  ? 166 LEU C CB  1 
ATOM   5836 C  CG  . LEU C 1 170 ? -50.756 18.996  45.67   1   50.17  ? 166 LEU C CG  1 
ATOM   5837 C  CD1 . LEU C 1 170 ? -51.608 17.778  45.992  1   46.55  ? 166 LEU C CD1 1 
ATOM   5838 C  CD2 . LEU C 1 170 ? -50.463 19.784  46.931  1   47.71  ? 166 LEU C CD2 1 
ATOM   5839 N  N   . TRP C 1 171 ? -49.941 19.796  42.136  1   57.97  ? 167 TRP C N   1 
ATOM   5840 C  CA  . TRP C 1 171 ? -50.675 20.724  41.285  1   56.18  ? 167 TRP C CA  1 
ATOM   5841 C  C   . TRP C 1 171 ? -51.314 20.043  40.065  1   57.08  ? 167 TRP C C   1 
ATOM   5842 O  O   . TRP C 1 171 ? -52.312 20.534  39.558  1   58.88  ? 167 TRP C O   1 
ATOM   5843 C  CB  . TRP C 1 171 ? -49.746 21.854  40.833  1   51.35  ? 167 TRP C CB  1 
ATOM   5844 C  CG  . TRP C 1 171 ? -49.236 22.721  41.943  1   56.24  ? 167 TRP C CG  1 
ATOM   5845 C  CD1 . TRP C 1 171 ? -49.538 22.66   43.275  1   58.92  ? 167 TRP C CD1 1 
ATOM   5846 C  CD2 . TRP C 1 171 ? -48.367 23.857  41.778  1   58.68  ? 167 TRP C CD2 1 
ATOM   5847 N  NE1 . TRP C 1 171 ? -48.903 23.662  43.953  1   54.71  ? 167 TRP C NE1 1 
ATOM   5848 C  CE2 . TRP C 1 171 ? -48.187 24.42   43.061  1   61.23  ? 167 TRP C CE2 1 
ATOM   5849 C  CE3 . TRP C 1 171 ? -47.735 24.449  40.678  1   60.82  ? 167 TRP C CE3 1 
ATOM   5850 C  CZ2 . TRP C 1 171 ? -47.392 25.551  43.262  1   63.75  ? 167 TRP C CZ2 1 
ATOM   5851 C  CZ3 . TRP C 1 171 ? -46.969 25.578  40.876  1   62.86  ? 167 TRP C CZ3 1 
ATOM   5852 C  CH2 . TRP C 1 171 ? -46.793 26.111  42.153  1   63.9   ? 167 TRP C CH2 1 
ATOM   5853 N  N   . TYR C 1 172 ? -50.735 18.927  39.594  1   54     ? 168 TYR C N   1 
ATOM   5854 C  CA  . TYR C 1 172 ? -51.093 18.294  38.33   1   50.96  ? 168 TYR C CA  1 
ATOM   5855 C  C   . TYR C 1 172 ? -51.773 16.962  38.613  1   51.39  ? 168 TYR C C   1 
ATOM   5856 O  O   . TYR C 1 172 ? -52.002 16.182  37.689  1   52.8   ? 168 TYR C O   1 
ATOM   5857 C  CB  . TYR C 1 172 ? -49.845 18.099  37.45   1   45.81  ? 168 TYR C CB  1 
ATOM   5858 C  CG  . TYR C 1 172 ? -49.151 19.426  37.189  1   46.06  ? 168 TYR C CG  1 
ATOM   5859 C  CD1 . TYR C 1 172 ? -49.583 20.261  36.17   1   43.98  ? 168 TYR C CD1 1 
ATOM   5860 C  CD2 . TYR C 1 172 ? -48.149 19.893  38.036  1   46.94  ? 168 TYR C CD2 1 
ATOM   5861 C  CE1 . TYR C 1 172 ? -49.011 21.502  35.971  1   46.5   ? 168 TYR C CE1 1 
ATOM   5862 C  CE2 . TYR C 1 172 ? -47.561 21.131  37.836  1   46.91  ? 168 TYR C CE2 1 
ATOM   5863 C  CZ  . TYR C 1 172 ? -47.998 21.943  36.802  1   49.95  ? 168 TYR C CZ  1 
ATOM   5864 O  OH  . TYR C 1 172 ? -47.449 23.184  36.597  1   57.12  ? 168 TYR C OH  1 
ATOM   5865 N  N   . ARG C 1 173 ? -52.127 16.734  39.884  1   50.25  ? 169 ARG C N   1 
ATOM   5866 C  CA  . ARG C 1 173 ? -52.712 15.467  40.304  1   50.11  ? 169 ARG C CA  1 
ATOM   5867 C  C   . ARG C 1 173 ? -54.221 15.45   40.069  1   53.07  ? 169 ARG C C   1 
ATOM   5868 O  O   . ARG C 1 173 ? -54.948 16.365  40.478  1   56.33  ? 169 ARG C O   1 
ATOM   5869 C  CB  . ARG C 1 173 ? -52.388 15.2    41.776  1   49.13  ? 169 ARG C CB  1 
ATOM   5870 C  CG  . ARG C 1 173 ? -52.704 13.775  42.2    1   50.45  ? 169 ARG C CG  1 
ATOM   5871 C  CD  . ARG C 1 173 ? -52.221 13.467  43.605  1   52.52  ? 169 ARG C CD  1 
ATOM   5872 N  NE  . ARG C 1 173 ? -50.789 13.689  43.83   1   52.86  ? 169 ARG C NE  1 
ATOM   5873 C  CZ  . ARG C 1 173 ? -50.262 14.115  44.983  1   55.91  ? 169 ARG C CZ  1 
ATOM   5874 N  NH1 . ARG C 1 173 ? -51.007 14.303  46.069  1   55.56  ? 169 ARG C NH1 1 
ATOM   5875 N  NH2 . ARG C 1 173 ? -48.965 14.312  45.068  1   54.9   ? 169 ARG C NH2 1 
ATOM   5876 N  N   . ALA C 1 174 ? -54.688 14.369  39.439  1   54.16  ? 170 ALA C N   1 
ATOM   5877 C  CA  . ALA C 1 174 ? -56.099 14.203  39.095  1   54.7   ? 170 ALA C CA  1 
ATOM   5878 C  C   . ALA C 1 174 ? -56.961 13.978  40.343  1   56.03  ? 170 ALA C C   1 
ATOM   5879 O  O   . ALA C 1 174 ? -56.527 13.416  41.349  1   59.06  ? 170 ALA C O   1 
ATOM   5880 C  CB  . ALA C 1 174 ? -56.24  13.078  38.092  1   49.55  ? 170 ALA C CB  1 
ATOM   5881 N  N   . PRO C 1 175 ? -58.236 14.4    40.333  1   55.36  ? 171 PRO C N   1 
ATOM   5882 C  CA  . PRO C 1 175 ? -59.096 14.208  41.498  1   57.9   ? 171 PRO C CA  1 
ATOM   5883 C  C   . PRO C 1 175 ? -59.323 12.764  41.95   1   62.47  ? 171 PRO C C   1 
ATOM   5884 O  O   . PRO C 1 175 ? -59.564 12.519  43.124  1   65.76  ? 171 PRO C O   1 
ATOM   5885 C  CB  . PRO C 1 175 ? -60.387 14.935  41.103  1   59.14  ? 171 PRO C CB  1 
ATOM   5886 C  CG  . PRO C 1 175 ? -60.349 14.932  39.594  1   57.75  ? 171 PRO C CG  1 
ATOM   5887 C  CD  . PRO C 1 175 ? -58.895 15.098  39.225  1   55.75  ? 171 PRO C CD  1 
ATOM   5888 N  N   . GLU C 1 176 ? -59.219 11.791  41.039  1   64.72  ? 172 GLU C N   1 
ATOM   5889 C  CA  . GLU C 1 176 ? -59.378 10.395  41.432  1   62.18  ? 172 GLU C CA  1 
ATOM   5890 C  C   . GLU C 1 176 ? -58.217 9.947   42.318  1   65.67  ? 172 GLU C C   1 
ATOM   5891 O  O   . GLU C 1 176 ? -58.4   9.102   43.194  1   69.93  ? 172 GLU C O   1 
ATOM   5892 C  CB  . GLU C 1 176 ? -59.551 9.445   40.25   1   62.14  ? 172 GLU C CB  1 
ATOM   5893 C  CG  . GLU C 1 176 ? -58.448 9.565   39.201  1   63.34  ? 172 GLU C CG  1 
ATOM   5894 C  CD  . GLU C 1 176 ? -58.73  10.466  38.013  1   66.15  ? 172 GLU C CD  1 
ATOM   5895 O  OE1 . GLU C 1 176 ? -58.272 10.097  36.904  1   64.55  ? 172 GLU C OE1 1 
ATOM   5896 O  OE2 . GLU C 1 176 ? -59.419 11.516  38.174  1   69.87  ? 172 GLU C OE2 1 
ATOM   5897 N  N   . ILE C 1 177 ? -57.014 10.494  42.088  1   65.46  ? 173 ILE C N   1 
ATOM   5898 C  CA  . ILE C 1 177 ? -55.891 10.144  42.949  1   64.39  ? 173 ILE C CA  1 
ATOM   5899 C  C   . ILE C 1 177 ? -56.022 10.868  44.291  1   69.68  ? 173 ILE C C   1 
ATOM   5900 O  O   . ILE C 1 177 ? -55.755 10.289  45.338  1   73.83  ? 173 ILE C O   1 
ATOM   5901 C  CB  . ILE C 1 177 ? -54.529 10.39   42.278  1   59.09  ? 173 ILE C CB  1 
ATOM   5902 C  CG1 . ILE C 1 177 ? -54.421 9.712   40.931  1   56.3   ? 173 ILE C CG1 1 
ATOM   5903 C  CG2 . ILE C 1 177 ? -53.389 9.952   43.196  1   61.36  ? 173 ILE C CG2 1 
ATOM   5904 C  CD1 . ILE C 1 177 ? -53.136 10.017  40.181  1   55.71  ? 173 ILE C CD1 1 
ATOM   5905 N  N   . LEU C 1 178 ? -56.465 12.127  44.258  1   70.39  ? 174 LEU C N   1 
ATOM   5906 C  CA  . LEU C 1 178 ? -56.651 12.909  45.471  1   67     ? 174 LEU C CA  1 
ATOM   5907 C  C   . LEU C 1 178 ? -57.656 12.256  46.42   1   68.56  ? 174 LEU C C   1 
ATOM   5908 O  O   . LEU C 1 178 ? -57.403 12.209  47.619  1   76.31  ? 174 LEU C O   1 
ATOM   5909 C  CB  . LEU C 1 178 ? -57.041 14.34   45.109  1   67.03  ? 174 LEU C CB  1 
ATOM   5910 C  CG  . LEU C 1 178 ? -55.908 15.24   44.602  1   66     ? 174 LEU C CG  1 
ATOM   5911 C  CD1 . LEU C 1 178 ? -56.518 16.47   43.952  1   67.94  ? 174 LEU C CD1 1 
ATOM   5912 C  CD2 . LEU C 1 178 ? -54.909 15.618  45.707  1   63.67  ? 174 LEU C CD2 1 
ATOM   5913 N  N   . LEU C 1 179 ? -58.771 11.74   45.891  1   70.35  ? 175 LEU C N   1 
ATOM   5914 C  CA  . LEU C 1 179 ? -59.793 11.054  46.678  1   73.42  ? 175 LEU C CA  1 
ATOM   5915 C  C   . LEU C 1 179 ? -59.494 9.555   46.861  1   77.8   ? 175 LEU C C   1 
ATOM   5916 O  O   . LEU C 1 179 ? -60.425 8.785   47.12   1   77.65  ? 175 LEU C O   1 
ATOM   5917 C  CB  . LEU C 1 179 ? -61.134 11.269  45.98   1   69.32  ? 175 LEU C CB  1 
ATOM   5918 C  CG  . LEU C 1 179 ? -61.56  12.728  45.828  1   71.59  ? 175 LEU C CG  1 
ATOM   5919 C  CD1 . LEU C 1 179 ? -62.838 12.918  45.046  1   69.63  ? 175 LEU C CD1 1 
ATOM   5920 C  CD2 . LEU C 1 179 ? -61.713 13.353  47.208  1   82.56  ? 175 LEU C CD2 1 
ATOM   5921 N  N   . GLY C 1 180 ? -58.215 9.154   46.709  1   71.88  ? 176 GLY C N   1 
ATOM   5922 C  CA  . GLY C 1 180 ? -57.703 7.81    46.953  1   70.79  ? 176 GLY C CA  1 
ATOM   5923 C  C   . GLY C 1 180 ? -58.552 6.7     46.336  1   69.92  ? 176 GLY C C   1 
ATOM   5924 O  O   . GLY C 1 180 ? -58.85  5.719   47.008  1   68.78  ? 176 GLY C O   1 
ATOM   5925 N  N   . CYS C 1 181 ? -58.955 6.882   45.072  1   70.59  ? 177 CYS C N   1 
ATOM   5926 C  CA  . CYS C 1 181 ? -59.622 5.822   44.331  1   74.18  ? 177 CYS C CA  1 
ATOM   5927 C  C   . CYS C 1 181 ? -58.697 4.62    44.256  1   70.42  ? 177 CYS C C   1 
ATOM   5928 O  O   . CYS C 1 181 ? -57.488 4.791   44.308  1   65.06  ? 177 CYS C O   1 
ATOM   5929 C  CB  . CYS C 1 181 ? -59.986 6.24    42.913  1   82.68  ? 177 CYS C CB  1 
ATOM   5930 S  SG  . CYS C 1 181 ? -61.437 7.329   42.852  1   102.75 ? 177 CYS C SG  1 
ATOM   5931 N  N   . LYS C 1 182 ? -59.285 3.42    44.19   1   77.07  ? 178 LYS C N   1 
ATOM   5932 C  CA  . LYS C 1 182 ? -58.529 2.177   44.162  1   80.41  ? 178 LYS C CA  1 
ATOM   5933 C  C   . LYS C 1 182 ? -57.745 2.068   42.855  1   77.26  ? 178 LYS C C   1 
ATOM   5934 O  O   . LYS C 1 182 ? -56.606 1.601   42.852  1   77.79  ? 178 LYS C O   1 
ATOM   5935 C  CB  . LYS C 1 182 ? -59.449 0.955   44.275  1   84.55  ? 178 LYS C CB  1 
ATOM   5936 C  CG  . LYS C 1 182 ? -58.773 -0.363  44.67   1   84.73  ? 178 LYS C CG  1 
ATOM   5937 C  CD  . LYS C 1 182 ? -59.773 -1.509  44.759  1   84.91  ? 178 LYS C CD  1 
ATOM   5938 C  CE  . LYS C 1 182 ? -59.24  -2.864  45.093  1   87.02  ? 178 LYS C CE  1 
ATOM   5939 N  NZ  . LYS C 1 182 ? -60.241 -3.897  44.775  1   84.52  ? 178 LYS C NZ  1 
ATOM   5940 N  N   . TYR C 1 183 ? -58.384 2.476   41.753  1   72     ? 179 TYR C N   1 
ATOM   5941 C  CA  . TYR C 1 183 ? -57.828 2.333   40.421  1   66.87  ? 179 TYR C CA  1 
ATOM   5942 C  C   . TYR C 1 183 ? -57.73  3.696   39.741  1   66.01  ? 179 TYR C C   1 
ATOM   5943 O  O   . TYR C 1 183 ? -58.614 4.543   39.887  1   73.2   ? 179 TYR C O   1 
ATOM   5944 C  CB  . TYR C 1 183 ? -58.714 1.437   39.553  1   69.79  ? 179 TYR C CB  1 
ATOM   5945 C  CG  . TYR C 1 183 ? -58.976 0.037   40.08   1   74.91  ? 179 TYR C CG  1 
ATOM   5946 C  CD1 . TYR C 1 183 ? -57.934 -0.859  40.284  1   78.68  ? 179 TYR C CD1 1 
ATOM   5947 C  CD2 . TYR C 1 183 ? -60.266 -0.413  40.305  1   79.12  ? 179 TYR C CD2 1 
ATOM   5948 C  CE1 . TYR C 1 183 ? -58.153 -2.143  40.758  1   80.13  ? 179 TYR C CE1 1 
ATOM   5949 C  CE2 . TYR C 1 183 ? -60.502 -1.696  40.771  1   85.88  ? 179 TYR C CE2 1 
ATOM   5950 C  CZ  . TYR C 1 183 ? -59.447 -2.563  41      1   87.22  ? 179 TYR C CZ  1 
ATOM   5951 O  OH  . TYR C 1 183 ? -59.691 -3.826  41.462  1   101.96 ? 179 TYR C OH  1 
ATOM   5952 N  N   . TYR C 1 184 ? -56.63  3.89    39.006  1   61.82  ? 180 TYR C N   1 
ATOM   5953 C  CA  . TYR C 1 184 ? -56.474 5.002   38.079  1   63.69  ? 180 TYR C CA  1 
ATOM   5954 C  C   . TYR C 1 184 ? -55.825 4.492   36.79   1   64.45  ? 180 TYR C C   1 
ATOM   5955 O  O   . TYR C 1 184 ? -55.201 3.432   36.764  1   65.49  ? 180 TYR C O   1 
ATOM   5956 C  CB  . TYR C 1 184 ? -55.709 6.184   38.685  1   63.01  ? 180 TYR C CB  1 
ATOM   5957 C  CG  . TYR C 1 184 ? -54.266 5.862   39.032  1   60.61  ? 180 TYR C CG  1 
ATOM   5958 C  CD1 . TYR C 1 184 ? -53.278 5.858   38.051  1   56.5   ? 180 TYR C CD1 1 
ATOM   5959 C  CD2 . TYR C 1 184 ? -53.902 5.533   40.338  1   60.29  ? 180 TYR C CD2 1 
ATOM   5960 C  CE1 . TYR C 1 184 ? -51.969 5.533   38.37   1   60.55  ? 180 TYR C CE1 1 
ATOM   5961 C  CE2 . TYR C 1 184 ? -52.59  5.213   40.665  1   58.03  ? 180 TYR C CE2 1 
ATOM   5962 C  CZ  . TYR C 1 184 ? -51.617 5.205   39.675  1   59.22  ? 180 TYR C CZ  1 
ATOM   5963 O  OH  . TYR C 1 184 ? -50.307 4.893   39.956  1   57.86  ? 180 TYR C OH  1 
ATOM   5964 N  N   . SER C 1 185 ? -55.972 5.286   35.726  1   66.87  ? 181 SER C N   1 
ATOM   5965 C  CA  . SER C 1 185 ? -55.62  4.868   34.38   1   65.53  ? 181 SER C CA  1 
ATOM   5966 C  C   . SER C 1 185 ? -55.089 6.06    33.587  1   59.22  ? 181 SER C C   1 
ATOM   5967 O  O   . SER C 1 185 ? -54.632 7.045   34.177  1   60.39  ? 181 SER C O   1 
ATOM   5968 C  CB  . SER C 1 185 ? -56.81  4.207   33.706  1   67.75  ? 181 SER C CB  1 
ATOM   5969 O  OG  . SER C 1 185 ? -56.537 3.818   32.363  1   67.56  ? 181 SER C OG  1 
ATOM   5970 N  N   . THR C 1 186 ? -55.168 5.945   32.253  1   57.56  ? 182 THR C N   1 
ATOM   5971 C  CA  . THR C 1 186 ? -54.593 6.888   31.307  1   60.64  ? 182 THR C CA  1 
ATOM   5972 C  C   . THR C 1 186 ? -55.192 8.277   31.518  1   62.75  ? 182 THR C C   1 
ATOM   5973 O  O   . THR C 1 186 ? -54.612 9.275   31.099  1   64.96  ? 182 THR C O   1 
ATOM   5974 C  CB  . THR C 1 186 ? -54.81  6.407   29.871  1   62.08  ? 182 THR C CB  1 
ATOM   5975 O  OG1 . THR C 1 186 ? -56.214 6.349   29.652  1   68.44  ? 182 THR C OG1 1 
ATOM   5976 C  CG2 . THR C 1 186 ? -54.188 5.051   29.596  1   55.99  ? 182 THR C CG2 1 
ATOM   5977 N  N   . ALA C 1 187 ? -56.352 8.334   32.179  1   64.29  ? 183 ALA C N   1 
ATOM   5978 C  CA  . ALA C 1 187 ? -57.022 9.602   32.433  1   64.86  ? 183 ALA C CA  1 
ATOM   5979 C  C   . ALA C 1 187 ? -56.145 10.559  33.255  1   61.02  ? 183 ALA C C   1 
ATOM   5980 O  O   . ALA C 1 187 ? -56.123 11.757  32.981  1   62.25  ? 183 ALA C O   1 
ATOM   5981 C  CB  . ALA C 1 187 ? -58.387 9.36    33.043  1   61.1   ? 183 ALA C CB  1 
ATOM   5982 N  N   . VAL C 1 188 ? -55.386 10.035  34.224  1   57     ? 184 VAL C N   1 
ATOM   5983 C  CA  . VAL C 1 188 ? -54.598 10.886  35.098  1   55.87  ? 184 VAL C CA  1 
ATOM   5984 C  C   . VAL C 1 188 ? -53.601 11.697  34.265  1   55.72  ? 184 VAL C C   1 
ATOM   5985 O  O   . VAL C 1 188 ? -53.33  12.855  34.57   1   61.54  ? 184 VAL C O   1 
ATOM   5986 C  CB  . VAL C 1 188 ? -53.914 10.148  36.268  1   53.93  ? 184 VAL C CB  1 
ATOM   5987 C  CG1 . VAL C 1 188 ? -54.863 9.178   36.956  1   53.88  ? 184 VAL C CG1 1 
ATOM   5988 C  CG2 . VAL C 1 188 ? -52.638 9.433   35.846  1   51.62  ? 184 VAL C CG2 1 
ATOM   5989 N  N   . ASP C 1 189 ? -53.086 11.105  33.187  1   53.56  ? 185 ASP C N   1 
ATOM   5990 C  CA  . ASP C 1 189 ? -52.114 11.783  32.347  1   54.9   ? 185 ASP C CA  1 
ATOM   5991 C  C   . ASP C 1 189 ? -52.784 12.885  31.536  1   54.43  ? 185 ASP C C   1 
ATOM   5992 O  O   . ASP C 1 189 ? -52.133 13.865  31.181  1   59.46  ? 185 ASP C O   1 
ATOM   5993 C  CB  . ASP C 1 189 ? -51.369 10.798  31.458  1   56.12  ? 185 ASP C CB  1 
ATOM   5994 C  CG  . ASP C 1 189 ? -50.251 10.027  32.152  1   59.9   ? 185 ASP C CG  1 
ATOM   5995 O  OD1 . ASP C 1 189 ? -49.771 10.492  33.22   1   54.68  ? 185 ASP C OD1 1 
ATOM   5996 O  OD2 . ASP C 1 189 ? -49.874 8.951   31.628  1   61.46  ? 185 ASP C OD2 1 
ATOM   5997 N  N   . ILE C 1 190 ? -54.068 12.705  31.206  1   55.4   ? 186 ILE C N   1 
ATOM   5998 C  CA  . ILE C 1 190 ? -54.802 13.714  30.451  1   56.54  ? 186 ILE C CA  1 
ATOM   5999 C  C   . ILE C 1 190 ? -55.085 14.91   31.354  1   56.26  ? 186 ILE C C   1 
ATOM   6000 O  O   . ILE C 1 190 ? -54.999 16.05   30.905  1   57.37  ? 186 ILE C O   1 
ATOM   6001 C  CB  . ILE C 1 190 ? -56.089 13.159  29.8    1   62.7   ? 186 ILE C CB  1 
ATOM   6002 C  CG1 . ILE C 1 190 ? -55.786 12.277  28.558  1   61.72  ? 186 ILE C CG1 1 
ATOM   6003 C  CG2 . ILE C 1 190 ? -57.092 14.275  29.463  1   58.26  ? 186 ILE C CG2 1 
ATOM   6004 C  CD1 . ILE C 1 190 ? -55.263 13.036  27.342  1   58.12  ? 186 ILE C CD1 1 
ATOM   6005 N  N   . TRP C 1 191 ? -55.428 14.636  32.619  1   53.25  ? 187 TRP C N   1 
ATOM   6006 C  CA  . TRP C 1 191 ? -55.717 15.693  33.568  1   53.76  ? 187 TRP C CA  1 
ATOM   6007 C  C   . TRP C 1 191 ? -54.52  16.64   33.643  1   54.52  ? 187 TRP C C   1 
ATOM   6008 O  O   . TRP C 1 191 ? -54.625 17.844  33.438  1   52.92  ? 187 TRP C O   1 
ATOM   6009 C  CB  . TRP C 1 191 ? -56.038 15.07   34.93   1   56.08  ? 187 TRP C CB  1 
ATOM   6010 C  CG  . TRP C 1 191 ? -56.299 16.114  35.981  1   58.76  ? 187 TRP C CG  1 
ATOM   6011 C  CD1 . TRP C 1 191 ? -55.364 16.722  36.765  1   56.59  ? 187 TRP C CD1 1 
ATOM   6012 C  CD2 . TRP C 1 191 ? -57.572 16.709  36.321  1   59.39  ? 187 TRP C CD2 1 
ATOM   6013 N  NE1 . TRP C 1 191 ? -55.97  17.626  37.594  1   57.96  ? 187 TRP C NE1 1 
ATOM   6014 C  CE2 . TRP C 1 191 ? -57.32  17.659  37.335  1   59.45  ? 187 TRP C CE2 1 
ATOM   6015 C  CE3 . TRP C 1 191 ? -58.891 16.522  35.883  1   60.9   ? 187 TRP C CE3 1 
ATOM   6016 C  CZ2 . TRP C 1 191 ? -58.34  18.422  37.916  1   58.78  ? 187 TRP C CZ2 1 
ATOM   6017 C  CZ3 . TRP C 1 191 ? -59.894 17.275  36.455  1   61.01  ? 187 TRP C CZ3 1 
ATOM   6018 C  CH2 . TRP C 1 191 ? -59.62  18.219  37.452  1   62.75  ? 187 TRP C CH2 1 
ATOM   6019 N  N   . SER C 1 192 ? -53.348 16.059  33.877  1   56.24  ? 188 SER C N   1 
ATOM   6020 C  CA  . SER C 1 192 ? -52.093 16.793  33.895  1   54.45  ? 188 SER C CA  1 
ATOM   6021 C  C   . SER C 1 192 ? -51.936 17.68   32.656  1   52.24  ? 188 SER C C   1 
ATOM   6022 O  O   . SER C 1 192 ? -51.596 18.857  32.775  1   51.19  ? 188 SER C O   1 
ATOM   6023 C  CB  . SER C 1 192 ? -50.912 15.845  34.08   1   54.94  ? 188 SER C CB  1 
ATOM   6024 O  OG  . SER C 1 192 ? -51.096 15.007  35.215  1   50.4   ? 188 SER C OG  1 
ATOM   6025 N  N   . LEU C 1 193 ? -52.152 17.108  31.468  1   49.64  ? 189 LEU C N   1 
ATOM   6026 C  CA  . LEU C 1 193 ? -51.978 17.871  30.246  1   50.89  ? 189 LEU C CA  1 
ATOM   6027 C  C   . LEU C 1 193 ? -52.984 19.011  30.218  1   53.91  ? 189 LEU C C   1 
ATOM   6028 O  O   . LEU C 1 193 ? -52.685 20.102  29.729  1   58.07  ? 189 LEU C O   1 
ATOM   6029 C  CB  . LEU C 1 193 ? -52.157 16.969  29.029  1   54.22  ? 189 LEU C CB  1 
ATOM   6030 C  CG  . LEU C 1 193 ? -50.943 16.144  28.599  1   55.06  ? 189 LEU C CG  1 
ATOM   6031 C  CD1 . LEU C 1 193 ? -51.134 15.677  27.174  1   52.3   ? 189 LEU C CD1 1 
ATOM   6032 C  CD2 . LEU C 1 193 ? -49.666 16.946  28.699  1   56.07  ? 189 LEU C CD2 1 
ATOM   6033 N  N   . GLY C 1 194 ? -54.183 18.736  30.742  1   53.23  ? 190 GLY C N   1 
ATOM   6034 C  CA  . GLY C 1 194 ? -55.219 19.745  30.842  1   53.82  ? 190 GLY C CA  1 
ATOM   6035 C  C   . GLY C 1 194 ? -54.739 20.935  31.663  1   55.56  ? 190 GLY C C   1 
ATOM   6036 O  O   . GLY C 1 194 ? -54.857 22.079  31.219  1   57.87  ? 190 GLY C O   1 
ATOM   6037 N  N   . CYS C 1 195 ? -54.164 20.624  32.834  1   53.9   ? 191 CYS C N   1 
ATOM   6038 C  CA  . CYS C 1 195 ? -53.548 21.603  33.717  1   56.56  ? 191 CYS C CA  1 
ATOM   6039 C  C   . CYS C 1 195 ? -52.407 22.343  33.014  1   55.17  ? 191 CYS C C   1 
ATOM   6040 O  O   . CYS C 1 195 ? -52.194 23.538  33.254  1   53.59  ? 191 CYS C O   1 
ATOM   6041 C  CB  . CYS C 1 195 ? -53.052 20.953  35.004  1   55.93  ? 191 CYS C CB  1 
ATOM   6042 S  SG  . CYS C 1 195 ? -54.366 20.168  35.969  1   58.31  ? 191 CYS C SG  1 
ATOM   6043 N  N   . ILE C 1 196 ? -51.682 21.636  32.143  1   50.55  ? 192 ILE C N   1 
ATOM   6044 C  CA  . ILE C 1 196 ? -50.573 22.257  31.436  1   55.03  ? 192 ILE C CA  1 
ATOM   6045 C  C   . ILE C 1 196 ? -51.085 23.16   30.314  1   59.08  ? 192 ILE C C   1 
ATOM   6046 O  O   . ILE C 1 196 ? -50.514 24.239  30.102  1   64.25  ? 192 ILE C O   1 
ATOM   6047 C  CB  . ILE C 1 196 ? -49.554 21.195  30.977  1   56.37  ? 192 ILE C CB  1 
ATOM   6048 C  CG1 . ILE C 1 196 ? -48.763 20.666  32.176  1   51.47  ? 192 ILE C CG1 1 
ATOM   6049 C  CG2 . ILE C 1 196 ? -48.62  21.727  29.884  1   52.85  ? 192 ILE C CG2 1 
ATOM   6050 C  CD1 . ILE C 1 196 ? -48.373 19.205  32.072  1   55.25  ? 192 ILE C CD1 1 
ATOM   6051 N  N   . PHE C 1 197 ? -52.15  22.725  29.606  1   58.5   ? 193 PHE C N   1 
ATOM   6052 C  CA  . PHE C 1 197 ? -52.787 23.563  28.596  1   54.03  ? 193 PHE C CA  1 
ATOM   6053 C  C   . PHE C 1 197 ? -53.139 24.918  29.215  1   53.52  ? 193 PHE C C   1 
ATOM   6054 O  O   . PHE C 1 197 ? -52.731 25.95   28.698  1   53.88  ? 193 PHE C O   1 
ATOM   6055 C  CB  . PHE C 1 197 ? -53.96  22.827  27.95   1   54.47  ? 193 PHE C CB  1 
ATOM   6056 C  CG  . PHE C 1 197 ? -54.7   23.546  26.832  1   54.87  ? 193 PHE C CG  1 
ATOM   6057 C  CD1 . PHE C 1 197 ? -54.115 24.603  26.137  1   57.6   ? 193 PHE C CD1 1 
ATOM   6058 C  CD2 . PHE C 1 197 ? -55.976 23.134  26.449  1   55.38  ? 193 PHE C CD2 1 
ATOM   6059 C  CE1 . PHE C 1 197 ? -54.806 25.252  25.113  1   62.64  ? 193 PHE C CE1 1 
ATOM   6060 C  CE2 . PHE C 1 197 ? -56.663 23.783  25.418  1   59.52  ? 193 PHE C CE2 1 
ATOM   6061 C  CZ  . PHE C 1 197 ? -56.076 24.836  24.74   1   60.16  ? 193 PHE C CZ  1 
ATOM   6062 N  N   . ALA C 1 198 ? -53.834 24.908  30.36   1   50.02  ? 194 ALA C N   1 
ATOM   6063 C  CA  . ALA C 1 198 ? -54.233 26.134  31.035  1   51.99  ? 194 ALA C CA  1 
ATOM   6064 C  C   . ALA C 1 198 ? -53.04  27.039  31.318  1   55.7   ? 194 ALA C C   1 
ATOM   6065 O  O   . ALA C 1 198 ? -53.125 28.268  31.15   1   58.97  ? 194 ALA C O   1 
ATOM   6066 C  CB  . ALA C 1 198 ? -54.928 25.797  32.322  1   51.64  ? 194 ALA C CB  1 
ATOM   6067 N  N   . GLU C 1 199 ? -51.966 26.408  31.813  1   52.7   ? 195 GLU C N   1 
ATOM   6068 C  CA  . GLU C 1 199 ? -50.784 27.095  32.309  1   56.3   ? 195 GLU C CA  1 
ATOM   6069 C  C   . GLU C 1 199 ? -50.041 27.783  31.154  1   60.34  ? 195 GLU C C   1 
ATOM   6070 O  O   . GLU C 1 199 ? -49.485 28.876  31.333  1   58.69  ? 195 GLU C O   1 
ATOM   6071 C  CB  . GLU C 1 199 ? -49.959 26.103  33.133  1   55.73  ? 195 GLU C CB  1 
ATOM   6072 C  CG  . GLU C 1 199 ? -48.822 26.706  33.96   1   57.58  ? 195 GLU C CG  1 
ATOM   6073 C  CD  . GLU C 1 199 ? -48.136 25.738  34.924  1   60.64  ? 195 GLU C CD  1 
ATOM   6074 O  OE1 . GLU C 1 199 ? -48.735 24.682  35.24   1   58.72  ? 195 GLU C OE1 1 
ATOM   6075 O  OE2 . GLU C 1 199 ? -46.984 26.015  35.344  1   63.42  ? 195 GLU C OE2 1 
ATOM   6076 N  N   . MET C 1 200 ? -50.044 27.154  29.964  1   59.43  ? 196 MET C N   1 
ATOM   6077 C  CA  . MET C 1 200 ? -49.399 27.752  28.797  1   59.61  ? 196 MET C CA  1 
ATOM   6078 C  C   . MET C 1 200 ? -50.097 29.062  28.406  1   62.6   ? 196 MET C C   1 
ATOM   6079 O  O   . MET C 1 200 ? -49.45  30.092  28.189  1   66.02  ? 196 MET C O   1 
ATOM   6080 C  CB  . MET C 1 200 ? -49.348 26.769  27.628  1   52.6   ? 196 MET C CB  1 
ATOM   6081 C  CG  . MET C 1 200 ? -48.21  25.787  27.712  1   53.66  ? 196 MET C CG  1 
ATOM   6082 S  SD  . MET C 1 200 ? -47.943 24.859  26.18   1   59.33  ? 196 MET C SD  1 
ATOM   6083 C  CE  . MET C 1 200 ? -49.277 23.661  26.075  1   46.91  ? 196 MET C CE  1 
ATOM   6084 N  N   . VAL C 1 201 ? -51.433 29.022  28.385  1   61.73  ? 197 VAL C N   1 
ATOM   6085 C  CA  . VAL C 1 201 ? -52.268 30.171  28.079  1   64.15  ? 197 VAL C CA  1 
ATOM   6086 C  C   . VAL C 1 201 ? -52.067 31.313  29.084  1   68.43  ? 197 VAL C C   1 
ATOM   6087 O  O   . VAL C 1 201 ? -51.965 32.457  28.645  1   73.86  ? 197 VAL C O   1 
ATOM   6088 C  CB  . VAL C 1 201 ? -53.748 29.749  28.036  1   62.52  ? 197 VAL C CB  1 
ATOM   6089 C  CG1 . VAL C 1 201 ? -54.684 30.959  28.027  1   60.01  ? 197 VAL C CG1 1 
ATOM   6090 C  CG2 . VAL C 1 201 ? -54.029 28.759  26.907  1   58.67  ? 197 VAL C CG2 1 
ATOM   6091 N  N   . THR C 1 202 ? -52.049 31.011  30.406  1   67.61  ? 198 THR C N   1 
ATOM   6092 C  CA  . THR C 1 202 ? -52.085 32.014  31.483  1   68.08  ? 198 THR C CA  1 
ATOM   6093 C  C   . THR C 1 202 ? -50.701 32.268  32.086  1   64.16  ? 198 THR C C   1 
ATOM   6094 O  O   . THR C 1 202 ? -50.55  33.215  32.874  1   60.87  ? 198 THR C O   1 
ATOM   6095 C  CB  . THR C 1 202 ? -53.009 31.642  32.649  1   66.86  ? 198 THR C CB  1 
ATOM   6096 O  OG1 . THR C 1 202 ? -52.419 30.501  33.277  1   76.28  ? 198 THR C OG1 1 
ATOM   6097 C  CG2 . THR C 1 202 ? -54.445 31.365  32.253  1   64.04  ? 198 THR C CG2 1 
ATOM   6098 N  N   . ARG C 1 203 ? -49.753 31.361  31.854  1   64.9   ? 199 ARG C N   1 
ATOM   6099 C  CA  . ARG C 1 203 ? -48.375 31.451  32.426  1   70.11  ? 199 ARG C CA  1 
ATOM   6100 C  C   . ARG C 1 203 ? -48.398 31.256  33.955  1   67.6   ? 199 ARG C C   1 
ATOM   6101 O  O   . ARG C 1 203 ? -47.334 31.43   34.568  1   65.88  ? 199 ARG C O   1 
ATOM   6102 C  CB  . ARG C 1 203 ? -47.615 32.688  31.935  1   72.9   ? 199 ARG C CB  1 
ATOM   6103 C  CG  . ARG C 1 203 ? -46.814 32.383  30.679  1   69.79  ? 199 ARG C CG  1 
ATOM   6104 C  CD  . ARG C 1 203 ? -47.476 33.006  29.469  1   83.44  ? 199 ARG C CD  1 
ATOM   6105 N  NE  . ARG C 1 203 ? -47.541 34.461  29.635  1   86.8   ? 199 ARG C NE  1 
ATOM   6106 C  CZ  . ARG C 1 203 ? -48.659 35.167  29.694  1   81.58  ? 199 ARG C CZ  1 
ATOM   6107 N  NH1 . ARG C 1 203 ? -48.61  36.442  30.029  1   77.55  ? 199 ARG C NH1 1 
ATOM   6108 N  NH2 . ARG C 1 203 ? -49.817 34.597  29.419  1   78.52  ? 199 ARG C NH2 1 
ATOM   6109 N  N   . ARG C 1 204 ? -49.542 30.904  34.541  1   70.8   ? 200 ARG C N   1 
ATOM   6110 C  CA  . ARG C 1 204 ? -49.619 30.574  35.957  1   67.59  ? 200 ARG C CA  1 
ATOM   6111 C  C   . ARG C 1 204 ? -50.277 29.204  36.075  1   66.58  ? 200 ARG C C   1 
ATOM   6112 O  O   . ARG C 1 204 ? -51.182 28.892  35.299  1   69.01  ? 200 ARG C O   1 
ATOM   6113 C  CB  . ARG C 1 204 ? -50.528 31.543  36.716  1   66     ? 200 ARG C CB  1 
ATOM   6114 C  CG  . ARG C 1 204 ? -50.241 33.001  36.416  1   77.91  ? 200 ARG C CG  1 
ATOM   6115 C  CD  . ARG C 1 204 ? -51.534 33.778  36.576  1   82.56  ? 200 ARG C CD  1 
ATOM   6116 N  NE  . ARG C 1 204 ? -51.321 35.221  36.429  1   99.37  ? 200 ARG C NE  1 
ATOM   6117 C  CZ  . ARG C 1 204 ? -52.072 36.101  35.751  1   111.14 ? 200 ARG C CZ  1 
ATOM   6118 N  NH1 . ARG C 1 204 ? -51.771 37.39   35.788  1   107.28 ? 200 ARG C NH1 1 
ATOM   6119 N  NH2 . ARG C 1 204 ? -53.13  35.702  35.059  1   121.2  ? 200 ARG C NH2 1 
ATOM   6120 N  N   . ALA C 1 205 ? -49.819 28.415  37.054  1   63.92  ? 201 ALA C N   1 
ATOM   6121 C  CA  . ALA C 1 205 ? -50.405 27.119  37.369  1   61.43  ? 201 ALA C CA  1 
ATOM   6122 C  C   . ALA C 1 205 ? -51.899 27.284  37.631  1   60.14  ? 201 ALA C C   1 
ATOM   6123 O  O   . ALA C 1 205 ? -52.292 28.269  38.261  1   63.59  ? 201 ALA C O   1 
ATOM   6124 C  CB  . ALA C 1 205 ? -49.697 26.546  38.577  1   63.41  ? 201 ALA C CB  1 
ATOM   6125 N  N   . LEU C 1 206 ? -52.704 26.313  37.16   1   54.09  ? 202 LEU C N   1 
ATOM   6126 C  CA  . LEU C 1 206 ? -54.161 26.358  37.247  1   54.83  ? 202 LEU C CA  1 
ATOM   6127 C  C   . LEU C 1 206 ? -54.66  26.036  38.655  1   56.7   ? 202 LEU C C   1 
ATOM   6128 O  O   . LEU C 1 206 ? -55.616 26.651  39.097  1   58.85  ? 202 LEU C O   1 
ATOM   6129 C  CB  . LEU C 1 206 ? -54.79  25.417  36.22   1   54.54  ? 202 LEU C CB  1 
ATOM   6130 C  CG  . LEU C 1 206 ? -56.31  25.23   36.283  1   54.28  ? 202 LEU C CG  1 
ATOM   6131 C  CD1 . LEU C 1 206 ? -57.031 26.537  35.893  1   52.54  ? 202 LEU C CD1 1 
ATOM   6132 C  CD2 . LEU C 1 206 ? -56.753 24.065  35.393  1   49.87  ? 202 LEU C CD2 1 
ATOM   6133 N  N   . PHE C 1 207 ? -54.052 25.05   39.333  1   56.64  ? 203 PHE C N   1 
ATOM   6134 C  CA  . PHE C 1 207 ? -54.456 24.657  40.677  1   57.72  ? 203 PHE C CA  1 
ATOM   6135 C  C   . PHE C 1 207 ? -53.241 24.57   41.608  1   58.94  ? 203 PHE C C   1 
ATOM   6136 O  O   . PHE C 1 207 ? -52.761 23.479  41.924  1   58.32  ? 203 PHE C O   1 
ATOM   6137 C  CB  . PHE C 1 207 ? -55.137 23.287  40.604  1   60.11  ? 203 PHE C CB  1 
ATOM   6138 C  CG  . PHE C 1 207 ? -56.361 23.201  39.704  1   60.67  ? 203 PHE C CG  1 
ATOM   6139 C  CD1 . PHE C 1 207 ? -57.396 24.114  39.822  1   61.49  ? 203 PHE C CD1 1 
ATOM   6140 C  CD2 . PHE C 1 207 ? -56.462 22.216  38.725  1   60.27  ? 203 PHE C CD2 1 
ATOM   6141 C  CE1 . PHE C 1 207 ? -58.494 24.039  38.98   1   63.36  ? 203 PHE C CE1 1 
ATOM   6142 C  CE2 . PHE C 1 207 ? -57.57  22.136  37.897  1   60.57  ? 203 PHE C CE2 1 
ATOM   6143 C  CZ  . PHE C 1 207 ? -58.593 23.043  38.033  1   62.7   ? 203 PHE C CZ  1 
ATOM   6144 N  N   . PRO C 1 208 ? -52.694 25.709  42.095  1   57.66  ? 204 PRO C N   1 
ATOM   6145 C  CA  . PRO C 1 208 ? -51.518 25.67   42.966  1   57.11  ? 204 PRO C CA  1 
ATOM   6146 C  C   . PRO C 1 208 ? -51.861 25.475  44.446  1   60.06  ? 204 PRO C C   1 
ATOM   6147 O  O   . PRO C 1 208 ? -51.785 26.409  45.248  1   73.99  ? 204 PRO C O   1 
ATOM   6148 C  CB  . PRO C 1 208 ? -50.922 27.054  42.64   1   56.13  ? 204 PRO C CB  1 
ATOM   6149 C  CG  . PRO C 1 208 ? -52.126 27.967  42.473  1   55.3   ? 204 PRO C CG  1 
ATOM   6150 C  CD  . PRO C 1 208 ? -53.2   27.073  41.875  1   55.94  ? 204 PRO C CD  1 
ATOM   6151 N  N   . GLY C 1 209 ? -52.245 24.245  44.8    1   58.46  ? 205 GLY C N   1 
ATOM   6152 C  CA  . GLY C 1 209 ? -52.631 23.915  46.163  1   58.53  ? 205 GLY C CA  1 
ATOM   6153 C  C   . GLY C 1 209 ? -51.416 23.674  47.052  1   58.3   ? 205 GLY C C   1 
ATOM   6154 O  O   . GLY C 1 209 ? -50.413 23.128  46.597  1   64.75  ? 205 GLY C O   1 
ATOM   6155 N  N   . ASP C 1 210 ? -51.532 24.075  48.319  1   63.82  ? 206 ASP C N   1 
ATOM   6156 C  CA  . ASP C 1 210 ? -50.459 23.977  49.298  1   68.74  ? 206 ASP C CA  1 
ATOM   6157 C  C   . ASP C 1 210 ? -50.695 22.794  50.229  1   67.25  ? 206 ASP C C   1 
ATOM   6158 O  O   . ASP C 1 210 ? -49.955 22.614  51.183  1   74.21  ? 206 ASP C O   1 
ATOM   6159 C  CB  . ASP C 1 210 ? -50.165 25.303  49.988  1   73.81  ? 206 ASP C CB  1 
ATOM   6160 C  CG  . ASP C 1 210 ? -51.307 25.92   50.786  1   85.07  ? 206 ASP C CG  1 
ATOM   6161 O  OD1 . ASP C 1 210 ? -52.431 25.364  50.777  1   88.51  ? 206 ASP C OD1 1 
ATOM   6162 O  OD2 . ASP C 1 210 ? -51.068 26.968  51.411  1   91.88  ? 206 ASP C OD2 1 
ATOM   6163 N  N   . SER C 1 211 ? -51.725 21.995  49.938  1   64.05  ? 207 SER C N   1 
ATOM   6164 C  CA  . SER C 1 211 ? -51.978 20.72   50.596  1   63.24  ? 207 SER C CA  1 
ATOM   6165 C  C   . SER C 1 211 ? -52.974 19.918  49.759  1   63.88  ? 207 SER C C   1 
ATOM   6166 O  O   . SER C 1 211 ? -53.473 20.429  48.761  1   67.45  ? 207 SER C O   1 
ATOM   6167 C  CB  . SER C 1 211 ? -52.477 20.923  52.012  1   63.4   ? 207 SER C CB  1 
ATOM   6168 O  OG  . SER C 1 211 ? -53.848 21.296  52.064  1   62.09  ? 207 SER C OG  1 
ATOM   6169 N  N   . GLU C 1 212 ? -53.286 18.682  50.178  1   65.38  ? 208 GLU C N   1 
ATOM   6170 C  CA  . GLU C 1 212 ? -54.202 17.824  49.435  1   67.5   ? 208 GLU C CA  1 
ATOM   6171 C  C   . GLU C 1 212 ? -55.654 18.277  49.552  1   69.02  ? 208 GLU C C   1 
ATOM   6172 O  O   . GLU C 1 212 ? -56.43  18.16   48.605  1   70.24  ? 208 GLU C O   1 
ATOM   6173 C  CB  . GLU C 1 212 ? -54.119 16.396  49.952  1   71.56  ? 208 GLU C CB  1 
ATOM   6174 C  CG  . GLU C 1 212 ? -52.985 15.652  49.264  1   81.84  ? 208 GLU C CG  1 
ATOM   6175 C  CD  . GLU C 1 212 ? -52.751 14.238  49.744  1   86.09  ? 208 GLU C CD  1 
ATOM   6176 O  OE1 . GLU C 1 212 ? -53.716 13.456  49.87   1   90.17  ? 208 GLU C OE1 1 
ATOM   6177 O  OE2 . GLU C 1 212 ? -51.566 13.929  49.966  1   84.71  ? 208 GLU C OE2 1 
ATOM   6178 N  N   . ILE C 1 213 ? -56.028 18.747  50.74   1   71.62  ? 209 ILE C N   1 
ATOM   6179 C  CA  . ILE C 1 213 ? -57.359 19.296  50.915  1   74.19  ? 209 ILE C CA  1 
ATOM   6180 C  C   . ILE C 1 213 ? -57.481 20.608  50.12   1   72.48  ? 209 ILE C C   1 
ATOM   6181 O  O   . ILE C 1 213 ? -58.494 20.85   49.469  1   74.34  ? 209 ILE C O   1 
ATOM   6182 C  CB  . ILE C 1 213 ? -57.695 19.422  52.415  1   76.66  ? 209 ILE C CB  1 
ATOM   6183 C  CG1 . ILE C 1 213 ? -59.169 19.746  52.647  1   84.12  ? 209 ILE C CG1 1 
ATOM   6184 C  CG2 . ILE C 1 213 ? -56.783 20.431  53.12   1   82.87  ? 209 ILE C CG2 1 
ATOM   6185 C  CD1 . ILE C 1 213 ? -60.125 18.638  52.242  1   87.77  ? 209 ILE C CD1 1 
ATOM   6186 N  N   . ASP C 1 214 ? -56.434 21.442  50.147  1   66.96  ? 210 ASP C N   1 
ATOM   6187 C  CA  . ASP C 1 214 ? -56.416 22.704  49.44   1   66.61  ? 210 ASP C CA  1 
ATOM   6188 C  C   . ASP C 1 214 ? -56.585 22.466  47.945  1   67.1   ? 210 ASP C C   1 
ATOM   6189 O  O   . ASP C 1 214 ? -57.359 23.174  47.294  1   67.63  ? 210 ASP C O   1 
ATOM   6190 C  CB  . ASP C 1 214 ? -55.147 23.489  49.715  1   67.69  ? 210 ASP C CB  1 
ATOM   6191 C  CG  . ASP C 1 214 ? -55.19  24.885  49.12   1   72.04  ? 210 ASP C CG  1 
ATOM   6192 O  OD1 . ASP C 1 214 ? -56.213 25.595  49.366  1   71.31  ? 210 ASP C OD1 1 
ATOM   6193 O  OD2 . ASP C 1 214 ? -54.219 25.239  48.408  1   69.19  ? 210 ASP C OD2 1 
ATOM   6194 N  N   . GLN C 1 215 ? -55.892 21.432  47.435  1   65.85  ? 211 GLN C N   1 
ATOM   6195 C  CA  . GLN C 1 215 ? -55.872 21.077  46.021  1   62.16  ? 211 GLN C CA  1 
ATOM   6196 C  C   . GLN C 1 215 ? -57.288 20.745  45.55   1   62     ? 211 GLN C C   1 
ATOM   6197 O  O   . GLN C 1 215 ? -57.722 21.244  44.525  1   64.65  ? 211 GLN C O   1 
ATOM   6198 C  CB  . GLN C 1 215 ? -54.893 19.924  45.82   1   62.83  ? 211 GLN C CB  1 
ATOM   6199 C  CG  . GLN C 1 215 ? -54.593 19.57   44.369  1   62.83  ? 211 GLN C CG  1 
ATOM   6200 C  CD  . GLN C 1 215 ? -53.843 20.644  43.613  1   62.2   ? 211 GLN C CD  1 
ATOM   6201 O  OE1 . GLN C 1 215 ? -53.016 21.384  44.167  1   59.8   ? 211 GLN C OE1 1 
ATOM   6202 N  NE2 . GLN C 1 215 ? -54.152 20.739  42.328  1   58.06  ? 211 GLN C NE2 1 
ATOM   6203 N  N   . LEU C 1 216 ? -58.033 19.974  46.352  1   62.25  ? 212 LEU C N   1 
ATOM   6204 C  CA  . LEU C 1 216 ? -59.408 19.613  46.058  1   60.23  ? 212 LEU C CA  1 
ATOM   6205 C  C   . LEU C 1 216 ? -60.326 20.83   45.991  1   62.76  ? 212 LEU C C   1 
ATOM   6206 O  O   . LEU C 1 216 ? -61.15  20.938  45.075  1   63.57  ? 212 LEU C O   1 
ATOM   6207 C  CB  . LEU C 1 216 ? -59.848 18.647  47.147  1   61.92  ? 212 LEU C CB  1 
ATOM   6208 C  CG  . LEU C 1 216 ? -59.53  17.18   46.866  1   64.94  ? 212 LEU C CG  1 
ATOM   6209 C  CD1 . LEU C 1 216 ? -59.696 16.34   48.119  1   66.33  ? 212 LEU C CD1 1 
ATOM   6210 C  CD2 . LEU C 1 216 ? -60.431 16.678  45.74   1   63.5   ? 212 LEU C CD2 1 
ATOM   6211 N  N   . PHE C 1 217 ? -60.203 21.727  46.975  1   63.12  ? 213 PHE C N   1 
ATOM   6212 C  CA  . PHE C 1 217 ? -61.049 22.912  47.026  1   66.93  ? 213 PHE C CA  1 
ATOM   6213 C  C   . PHE C 1 217 ? -60.808 23.793  45.798  1   68.88  ? 213 PHE C C   1 
ATOM   6214 O  O   . PHE C 1 217 ? -61.774 24.226  45.172  1   73.12  ? 213 PHE C O   1 
ATOM   6215 C  CB  . PHE C 1 217 ? -60.968 23.664  48.36   1   68.79  ? 213 PHE C CB  1 
ATOM   6216 C  CG  . PHE C 1 217 ? -61.442 22.902  49.6    1   69.49  ? 213 PHE C CG  1 
ATOM   6217 C  CD1 . PHE C 1 217 ? -62.104 21.68   49.497  1   69.53  ? 213 PHE C CD1 1 
ATOM   6218 C  CD2 . PHE C 1 217 ? -61.157 23.372  50.877  1   65.62  ? 213 PHE C CD2 1 
ATOM   6219 C  CE1 . PHE C 1 217 ? -62.516 21.004  50.634  1   71.41  ? 213 PHE C CE1 1 
ATOM   6220 C  CE2 . PHE C 1 217 ? -61.569 22.691  52.01   1   66.76  ? 213 PHE C CE2 1 
ATOM   6221 C  CZ  . PHE C 1 217 ? -62.258 21.516  51.892  1   69.95  ? 213 PHE C CZ  1 
ATOM   6222 N  N   . ARG C 1 218 ? -59.527 23.974  45.423  1   66.09  ? 214 ARG C N   1 
ATOM   6223 C  CA  . ARG C 1 218 ? -59.125 24.81   44.299  1   62.97  ? 214 ARG C CA  1 
ATOM   6224 C  C   . ARG C 1 218 ? -59.754 24.338  42.985  1   63.48  ? 214 ARG C C   1 
ATOM   6225 O  O   . ARG C 1 218 ? -60.112 25.166  42.144  1   64.55  ? 214 ARG C O   1 
ATOM   6226 C  CB  . ARG C 1 218 ? -57.601 24.889  44.202  1   60.47  ? 214 ARG C CB  1 
ATOM   6227 C  CG  . ARG C 1 218 ? -56.962 25.731  45.298  1   62.9   ? 214 ARG C CG  1 
ATOM   6228 C  CD  . ARG C 1 218 ? -55.49  25.893  45.014  1   61.45  ? 214 ARG C CD  1 
ATOM   6229 N  NE  . ARG C 1 218 ? -54.862 26.658  46.088  1   67.59  ? 214 ARG C NE  1 
ATOM   6230 C  CZ  . ARG C 1 218 ? -54.656 27.958  46.031  1   72.13  ? 214 ARG C CZ  1 
ATOM   6231 N  NH1 . ARG C 1 218 ? -54.917 28.611  44.91   1   76.57  ? 214 ARG C NH1 1 
ATOM   6232 N  NH2 . ARG C 1 218 ? -54.196 28.584  47.098  1   73.5   ? 214 ARG C NH2 1 
ATOM   6233 N  N   . ILE C 1 219 ? -59.916 23.015  42.835  1   61.58  ? 215 ILE C N   1 
ATOM   6234 C  CA  . ILE C 1 219 ? -60.521 22.417  41.652  1   63.67  ? 215 ILE C CA  1 
ATOM   6235 C  C   . ILE C 1 219 ? -62.046 22.624  41.655  1   69.37  ? 215 ILE C C   1 
ATOM   6236 O  O   . ILE C 1 219 ? -62.617 23.085  40.657  1   70.43  ? 215 ILE C O   1 
ATOM   6237 C  CB  . ILE C 1 219 ? -60.094 20.939  41.54   1   57.17  ? 215 ILE C CB  1 
ATOM   6238 C  CG1 . ILE C 1 219 ? -58.606 20.833  41.179  1   53.28  ? 215 ILE C CG1 1 
ATOM   6239 C  CG2 . ILE C 1 219 ? -60.968 20.158  40.559  1   57.62  ? 215 ILE C CG2 1 
ATOM   6240 C  CD1 . ILE C 1 219 ? -57.966 19.538  41.678  1   49.99  ? 215 ILE C CD1 1 
ATOM   6241 N  N   . PHE C 1 220 ? -62.668 22.275  42.78   1   72     ? 216 PHE C N   1 
ATOM   6242 C  CA  . PHE C 1 220 ? -64.137 22.395  42.92   1   72.47  ? 216 PHE C CA  1 
ATOM   6243 C  C   . PHE C 1 220 ? -64.535 23.837  42.761  1   77.43  ? 216 PHE C C   1 
ATOM   6244 O  O   . PHE C 1 220 ? -65.597 24.127  42.205  1   82.01  ? 216 PHE C O   1 
ATOM   6245 C  CB  . PHE C 1 220 ? -64.471 21.919  44.332  1   70.67  ? 216 PHE C CB  1 
ATOM   6246 C  CG  . PHE C 1 220 ? -64.213 20.462  44.684  1   72.47  ? 216 PHE C CG  1 
ATOM   6247 C  CD1 . PHE C 1 220 ? -63.714 19.565  43.749  1   71.75  ? 216 PHE C CD1 1 
ATOM   6248 C  CD2 . PHE C 1 220 ? -64.47  19.998  45.966  1   77.23  ? 216 PHE C CD2 1 
ATOM   6249 C  CE1 . PHE C 1 220 ? -63.481 18.246  44.091  1   76.74  ? 216 PHE C CE1 1 
ATOM   6250 C  CE2 . PHE C 1 220 ? -64.236 18.677  46.301  1   79.02  ? 216 PHE C CE2 1 
ATOM   6251 C  CZ  . PHE C 1 220 ? -63.748 17.804  45.362  1   75.39  ? 216 PHE C CZ  1 
ATOM   6252 N  N   . ARG C 1 221 ? -63.689 24.746  43.231  1   80.61  ? 217 ARG C N   1 
ATOM   6253 C  CA  . ARG C 1 221 ? -64.061 26.181  43.199  1   85.66  ? 217 ARG C CA  1 
ATOM   6254 C  C   . ARG C 1 221 ? -64.011 26.703  41.759  1   86.44  ? 217 ARG C C   1 
ATOM   6255 O  O   . ARG C 1 221 ? -64.647 27.736  41.492  1   97.42  ? 217 ARG C O   1 
ATOM   6256 C  CB  . ARG C 1 221 ? -63.153 26.974  44.143  1   89.51  ? 217 ARG C CB  1 
ATOM   6257 C  CG  . ARG C 1 221 ? -61.902 27.59   43.543  1   105.64 ? 217 ARG C CG  1 
ATOM   6258 C  CD  . ARG C 1 221 ? -61.271 28.519  44.558  1   117.56 ? 217 ARG C CD  1 
ATOM   6259 N  NE  . ARG C 1 221 ? -60.148 29.244  43.96   1   139.56 ? 217 ARG C NE  1 
ATOM   6260 C  CZ  . ARG C 1 221 ? -58.914 28.773  43.901  1   154.05 ? 217 ARG C CZ  1 
ATOM   6261 N  NH1 . ARG C 1 221 ? -58.114 28.912  44.941  1   162.46 ? 217 ARG C NH1 1 
ATOM   6262 N  NH2 . ARG C 1 221 ? -58.485 28.169  42.807  1   162.59 ? 217 ARG C NH2 1 
ATOM   6263 N  N   . THR C 1 222 ? -63.319 26.001  40.868  1   86.29  ? 218 THR C N   1 
ATOM   6264 C  CA  . THR C 1 222 ? -63.154 26.502  39.493  1   89.32  ? 218 THR C CA  1 
ATOM   6265 C  C   . THR C 1 222 ? -63.981 25.661  38.555  1   88.43  ? 218 THR C C   1 
ATOM   6266 O  O   . THR C 1 222 ? -64.512 26.215  37.576  1   94     ? 218 THR C O   1 
ATOM   6267 C  CB  . THR C 1 222 ? -61.665 26.478  39.151  1   87.62  ? 218 THR C CB  1 
ATOM   6268 O  OG1 . THR C 1 222 ? -61.107 27.597  39.832  1   85.05  ? 218 THR C OG1 1 
ATOM   6269 C  CG2 . THR C 1 222 ? -61.389 26.596  37.664  1   87.72  ? 218 THR C CG2 1 
ATOM   6270 N  N   . LEU C 1 223 ? -64.148 24.381  38.866  1   84.92  ? 219 LEU C N   1 
ATOM   6271 C  CA  . LEU C 1 223 ? -64.841 23.496  37.939  1   89.58  ? 219 LEU C CA  1 
ATOM   6272 C  C   . LEU C 1 223 ? -66.231 23.124  38.445  1   92.76  ? 219 LEU C C   1 
ATOM   6273 O  O   . LEU C 1 223 ? -67.023 22.557  37.689  1   93.92  ? 219 LEU C O   1 
ATOM   6274 C  CB  . LEU C 1 223 ? -64.014 22.238  37.69   1   86.02  ? 219 LEU C CB  1 
ATOM   6275 C  CG  . LEU C 1 223 ? -62.61  22.429  37.115  1   77.53  ? 219 LEU C CG  1 
ATOM   6276 C  CD1 . LEU C 1 223 ? -61.878 21.108  37.107  1   72.21  ? 219 LEU C CD1 1 
ATOM   6277 C  CD2 . LEU C 1 223 ? -62.689 23.019  35.725  1   75.15  ? 219 LEU C CD2 1 
ATOM   6278 N  N   . GLY C 1 224 ? -66.501 23.428  39.72   1   91.22  ? 220 GLY C N   1 
ATOM   6279 C  CA  . GLY C 1 224 ? -67.777 23.09   40.326  1   93.97  ? 220 GLY C CA  1 
ATOM   6280 C  C   . GLY C 1 224 ? -67.609 21.906  41.266  1   94.12  ? 220 GLY C C   1 
ATOM   6281 O  O   . GLY C 1 224 ? -66.855 20.98   40.977  1   96.96  ? 220 GLY C O   1 
ATOM   6282 N  N   . THR C 1 225 ? -68.272 21.969  42.419  1   94.62  ? 221 THR C N   1 
ATOM   6283 C  CA  . THR C 1 225 ? -68.187 20.83   43.311  1   98.06  ? 221 THR C CA  1 
ATOM   6284 C  C   . THR C 1 225 ? -68.886 19.682  42.591  1   99.2   ? 221 THR C C   1 
ATOM   6285 O  O   . THR C 1 225 ? -70.056 19.788  42.231  1   98.72  ? 221 THR C O   1 
ATOM   6286 C  CB  . THR C 1 225 ? -68.735 21.123  44.71   1   99.07  ? 221 THR C CB  1 
ATOM   6287 O  OG1 . THR C 1 225 ? -68.038 22.27   45.201  1   94.04  ? 221 THR C OG1 1 
ATOM   6288 C  CG2 . THR C 1 225 ? -68.5   19.956  45.656  1   97.72  ? 221 THR C CG2 1 
ATOM   6289 N  N   . PRO C 1 226 ? -68.154 18.592  42.285  1   104.8  ? 222 PRO C N   1 
ATOM   6290 C  CA  . PRO C 1 226 ? -68.732 17.471  41.535  1   111.21 ? 222 PRO C CA  1 
ATOM   6291 C  C   . PRO C 1 226 ? -69.84  16.784  42.343  1   116.09 ? 222 PRO C C   1 
ATOM   6292 O  O   . PRO C 1 226 ? -69.685 16.589  43.547  1   109.85 ? 222 PRO C O   1 
ATOM   6293 C  CB  . PRO C 1 226 ? -67.486 16.577  41.286  1   105.02 ? 222 PRO C CB  1 
ATOM   6294 C  CG  . PRO C 1 226 ? -66.563 16.897  42.454  1   101.32 ? 222 PRO C CG  1 
ATOM   6295 C  CD  . PRO C 1 226 ? -66.746 18.392  42.676  1   100.82 ? 222 PRO C CD  1 
ATOM   6296 N  N   . ASP C 1 227 ? -70.962 16.445  41.68   1   121.27 ? 223 ASP C N   1 
ATOM   6297 C  CA  . ASP C 1 227 ? -72.083 15.715  42.272  1   117.22 ? 223 ASP C CA  1 
ATOM   6298 C  C   . ASP C 1 227 ? -72.218 14.366  41.563  1   109.91 ? 223 ASP C C   1 
ATOM   6299 O  O   . ASP C 1 227 ? -71.415 14.065  40.688  1   106.21 ? 223 ASP C O   1 
ATOM   6300 C  CB  . ASP C 1 227 ? -73.378 16.515  42.205  1   123.88 ? 223 ASP C CB  1 
ATOM   6301 C  CG  . ASP C 1 227 ? -73.785 16.991  40.814  1   134.02 ? 223 ASP C CG  1 
ATOM   6302 O  OD1 . ASP C 1 227 ? -72.886 17.077  39.937  1   141.26 ? 223 ASP C OD1 1 
ATOM   6303 O  OD2 . ASP C 1 227 ? -74.999 17.245  40.61   1   134.29 ? 223 ASP C OD2 1 
ATOM   6304 N  N   . GLU C 1 228 ? -73.249 13.581  41.912  1   112.85 ? 224 GLU C N   1 
ATOM   6305 C  CA  . GLU C 1 228 ? -73.44  12.239  41.377  1   109.65 ? 224 GLU C CA  1 
ATOM   6306 C  C   . GLU C 1 228 ? -73.889 12.277  39.914  1   111.69 ? 224 GLU C C   1 
ATOM   6307 O  O   . GLU C 1 228 ? -73.804 11.264  39.22   1   116.04 ? 224 GLU C O   1 
ATOM   6308 C  CB  . GLU C 1 228 ? -74.414 11.451  42.259  1   107.74 ? 224 GLU C CB  1 
ATOM   6309 C  CG  . GLU C 1 228 ? -73.763 10.824  43.489  1   110.4  ? 224 GLU C CG  1 
ATOM   6310 C  CD  . GLU C 1 228 ? -72.699 9.758   43.242  1   115.37 ? 224 GLU C CD  1 
ATOM   6311 O  OE1 . GLU C 1 228 ? -73.061 8.715   42.645  1   116.73 ? 224 GLU C OE1 1 
ATOM   6312 O  OE2 . GLU C 1 228 ? -71.526 9.959   43.648  1   117.13 ? 224 GLU C OE2 1 
ATOM   6313 N  N   . VAL C 1 229 ? -74.359 13.441  39.45   1   112.16 ? 225 VAL C N   1 
ATOM   6314 C  CA  . VAL C 1 229 ? -74.881 13.58   38.097  1   112.68 ? 225 VAL C CA  1 
ATOM   6315 C  C   . VAL C 1 229 ? -73.782 14.093  37.163  1   107.29 ? 225 VAL C C   1 
ATOM   6316 O  O   . VAL C 1 229 ? -73.916 13.968  35.951  1   110.43 ? 225 VAL C O   1 
ATOM   6317 C  CB  . VAL C 1 229 ? -76.19  14.392  37.963  1   112.29 ? 225 VAL C CB  1 
ATOM   6318 C  CG1 . VAL C 1 229 ? -77.074 14.249  39.197  1   108.98 ? 225 VAL C CG1 1 
ATOM   6319 C  CG2 . VAL C 1 229 ? -75.942 15.871  37.671  1   111.51 ? 225 VAL C CG2 1 
ATOM   6320 N  N   . VAL C 1 230 ? -72.711 14.67   37.727  1   106.28 ? 226 VAL C N   1 
ATOM   6321 C  CA  . VAL C 1 230 ? -71.525 15.059  36.971  1   104.92 ? 226 VAL C CA  1 
ATOM   6322 C  C   . VAL C 1 230 ? -70.533 13.891  36.957  1   105.52 ? 226 VAL C C   1 
ATOM   6323 O  O   . VAL C 1 230 ? -69.809 13.663  35.985  1   103.04 ? 226 VAL C O   1 
ATOM   6324 C  CB  . VAL C 1 230 ? -70.884 16.348  37.53   1   101.77 ? 226 VAL C CB  1 
ATOM   6325 C  CG1 . VAL C 1 230 ? -69.371 16.371  37.343  1   95.52  ? 226 VAL C CG1 1 
ATOM   6326 C  CG2 . VAL C 1 230 ? -71.526 17.617  36.969  1   100.91 ? 226 VAL C CG2 1 
ATOM   6327 N  N   . TRP C 1 231 ? -70.501 13.158  38.07   1   108.02 ? 227 TRP C N   1 
ATOM   6328 C  CA  . TRP C 1 231 ? -69.515 12.12   38.292  1   104.66 ? 227 TRP C CA  1 
ATOM   6329 C  C   . TRP C 1 231 ? -70.155 11.067  39.184  1   106.91 ? 227 TRP C C   1 
ATOM   6330 O  O   . TRP C 1 231 ? -70.092 11.155  40.408  1   108.23 ? 227 TRP C O   1 
ATOM   6331 C  CB  . TRP C 1 231 ? -68.251 12.737  38.91   1   106    ? 227 TRP C CB  1 
ATOM   6332 C  CG  . TRP C 1 231 ? -67.062 11.822  39.063  1   104.73 ? 227 TRP C CG  1 
ATOM   6333 C  CD1 . TRP C 1 231 ? -66.924 10.529  38.646  1   107.2  ? 227 TRP C CD1 1 
ATOM   6334 C  CD2 . TRP C 1 231 ? -65.812 12.176  39.692  1   101.59 ? 227 TRP C CD2 1 
ATOM   6335 N  NE1 . TRP C 1 231 ? -65.687 10.05   38.981  1   109.06 ? 227 TRP C NE1 1 
ATOM   6336 C  CE2 . TRP C 1 231 ? -64.98  11.037  39.617  1   103.91 ? 227 TRP C CE2 1 
ATOM   6337 C  CE3 . TRP C 1 231 ? -65.322 13.336  40.308  1   97.09  ? 227 TRP C CE3 1 
ATOM   6338 C  CZ2 . TRP C 1 231 ? -63.686 11.032  40.138  1   97.25  ? 227 TRP C CZ2 1 
ATOM   6339 C  CZ3 . TRP C 1 231 ? -64.042 13.334  40.819  1   95.87  ? 227 TRP C CZ3 1 
ATOM   6340 C  CH2 . TRP C 1 231 ? -63.237 12.194  40.73   1   99.83  ? 227 TRP C CH2 1 
ATOM   6341 N  N   . PRO C 1 232 ? -70.84  10.072  38.577  1   113.37 ? 228 PRO C N   1 
ATOM   6342 C  CA  . PRO C 1 232 ? -71.436 8.97    39.336  1   116.37 ? 228 PRO C CA  1 
ATOM   6343 C  C   . PRO C 1 232 ? -70.324 8.298   40.135  1   112.85 ? 228 PRO C C   1 
ATOM   6344 O  O   . PRO C 1 232 ? -69.224 8.114   39.62   1   106.34 ? 228 PRO C O   1 
ATOM   6345 C  CB  . PRO C 1 232 ? -72.008 8.038   38.244  1   114.53 ? 228 PRO C CB  1 
ATOM   6346 C  CG  . PRO C 1 232 ? -72.162 8.921   37.022  1   108.19 ? 228 PRO C CG  1 
ATOM   6347 C  CD  . PRO C 1 232 ? -71.055 9.956   37.125  1   109.52 ? 228 PRO C CD  1 
ATOM   6348 N  N   . GLY C 1 233 ? -70.61  7.964   41.397  1   118.51 ? 229 GLY C N   1 
ATOM   6349 C  CA  . GLY C 1 233 ? -69.62  7.333   42.254  1   122.98 ? 229 GLY C CA  1 
ATOM   6350 C  C   . GLY C 1 233 ? -68.794 8.313   43.094  1   122.3  ? 229 GLY C C   1 
ATOM   6351 O  O   . GLY C 1 233 ? -68.163 7.879   44.06   1   129.32 ? 229 GLY C O   1 
ATOM   6352 N  N   . VAL C 1 234 ? -68.815 9.598   42.731  1   110.05 ? 230 VAL C N   1 
ATOM   6353 C  CA  . VAL C 1 234 ? -67.962 10.604  43.432  1   103.59 ? 230 VAL C CA  1 
ATOM   6354 C  C   . VAL C 1 234 ? -68.233 10.567  44.942  1   110.27 ? 230 VAL C C   1 
ATOM   6355 O  O   . VAL C 1 234 ? -67.258 10.581  45.705  1   111.72 ? 230 VAL C O   1 
ATOM   6356 C  CB  . VAL C 1 234 ? -68.134 12.028  42.862  1   98.31  ? 230 VAL C CB  1 
ATOM   6357 C  CG1 . VAL C 1 234 ? -69.503 12.629  43.145  1   101.14 ? 230 VAL C CG1 1 
ATOM   6358 C  CG2 . VAL C 1 234 ? -67.037 12.965  43.349  1   93.36  ? 230 VAL C CG2 1 
ATOM   6359 N  N   . THR C 1 235 ? -69.495 10.485  45.359  1   114.18 ? 231 THR C N   1 
ATOM   6360 C  CA  . THR C 1 235 ? -69.819 10.565  46.799  1   117.25 ? 231 THR C CA  1 
ATOM   6361 C  C   . THR C 1 235 ? -69.404 9.292   47.489  1   117.5  ? 231 THR C C   1 
ATOM   6362 O  O   . THR C 1 235 ? -69.261 9.312   48.724  1   120.6  ? 231 THR C O   1 
ATOM   6363 C  CB  . THR C 1 235 ? -71.311 10.837  46.955  1   118.87 ? 231 THR C CB  1 
ATOM   6364 O  OG1 . THR C 1 235 ? -71.937 9.719   46.337  1   128.07 ? 231 THR C OG1 1 
ATOM   6365 C  CG2 . THR C 1 235 ? -71.735 12.129  46.281  1   113.3  ? 231 THR C CG2 1 
ATOM   6366 N  N   . SER C 1 236 ? -69.217 8.22    46.724  1   116.85 ? 232 SER C N   1 
ATOM   6367 C  CA  . SER C 1 236 ? -68.832 6.914   47.308  1   117.48 ? 232 SER C CA  1 
ATOM   6368 C  C   . SER C 1 236 ? -67.307 6.844   47.411  1   114.67 ? 232 SER C C   1 
ATOM   6369 O  O   . SER C 1 236 ? -66.793 5.84    47.942  1   112.88 ? 232 SER C O   1 
ATOM   6370 C  CB  . SER C 1 236 ? -69.361 5.795   46.475  1   113.91 ? 232 SER C CB  1 
ATOM   6371 O  OG  . SER C 1 236 ? -68.529 5.589   45.342  1   120.43 ? 232 SER C OG  1 
ATOM   6372 N  N   . MET C 1 237 ? -66.621 7.876   46.926  1   113.99 ? 233 MET C N   1 
ATOM   6373 C  CA  . MET C 1 237 ? -65.139 7.843   46.909  1   113.37 ? 233 MET C CA  1 
ATOM   6374 C  C   . MET C 1 237 ? -64.594 7.891   48.342  1   108.93 ? 233 MET C C   1 
ATOM   6375 O  O   . MET C 1 237 ? -65.1   8.686   49.155  1   109.7  ? 233 MET C O   1 
ATOM   6376 C  CB  . MET C 1 237 ? -64.585 9.007   46.086  1   119.91 ? 233 MET C CB  1 
ATOM   6377 C  CG  . MET C 1 237 ? -64.982 8.953   44.633  1   123.44 ? 233 MET C CG  1 
ATOM   6378 S  SD  . MET C 1 237 ? -64.315 7.518   43.77   1   132.83 ? 233 MET C SD  1 
ATOM   6379 C  CE  . MET C 1 237 ? -64.975 7.783   42.119  1   137.65 ? 233 MET C CE  1 
ATOM   6380 N  N   . PRO C 1 238 ? -63.572 7.077   48.666  1   104.21 ? 234 PRO C N   1 
ATOM   6381 C  CA  . PRO C 1 238 ? -63.029 7.035   50.016  1   107.32 ? 234 PRO C CA  1 
ATOM   6382 C  C   . PRO C 1 238 ? -62.811 8.361   50.742  1   106.04 ? 234 PRO C C   1 
ATOM   6383 O  O   . PRO C 1 238 ? -63.272 8.492   51.888  1   103.05 ? 234 PRO C O   1 
ATOM   6384 C  CB  . PRO C 1 238 ? -61.692 6.344   49.708  1   108.43 ? 234 PRO C CB  1 
ATOM   6385 C  CG  . PRO C 1 238 ? -62.035 5.35    48.635  1   104.24 ? 234 PRO C CG  1 
ATOM   6386 C  CD  . PRO C 1 238 ? -62.926 6.17    47.733  1   100.57 ? 234 PRO C CD  1 
ATOM   6387 N  N   . ASP C 1 239 ? -62.114 9.309   50.116  1   104.51 ? 235 ASP C N   1 
ATOM   6388 C  CA  . ASP C 1 239 ? -61.758 10.585  50.796  1   105.57 ? 235 ASP C CA  1 
ATOM   6389 C  C   . ASP C 1 239 ? -62.805 11.664  50.512  1   112.07 ? 235 ASP C C   1 
ATOM   6390 O  O   . ASP C 1 239 ? -62.634 12.784  51.021  1   120.83 ? 235 ASP C O   1 
ATOM   6391 C  CB  . ASP C 1 239 ? -60.345 11.01   50.436  1   103.26 ? 235 ASP C CB  1 
ATOM   6392 C  CG  . ASP C 1 239 ? -59.271 9.964   50.683  1   104.99 ? 235 ASP C CG  1 
ATOM   6393 O  OD1 . ASP C 1 239 ? -59.465 9.133   51.592  1   106.88 ? 235 ASP C OD1 1 
ATOM   6394 O  OD2 . ASP C 1 239 ? -58.251 9.99    49.966  1   105.78 ? 235 ASP C OD2 1 
ATOM   6395 N  N   . TYR C 1 240 ? -63.827 11.363  49.713  1   112.25 ? 236 TYR C N   1 
ATOM   6396 C  CA  . TYR C 1 240 ? -64.919 12.308  49.505  1   111.6  ? 236 TYR C CA  1 
ATOM   6397 C  C   . TYR C 1 240 ? -65.588 12.594  50.853  1   117.25 ? 236 TYR C C   1 
ATOM   6398 O  O   . TYR C 1 240 ? -65.633 11.717  51.707  1   122.33 ? 236 TYR C O   1 
ATOM   6399 C  CB  . TYR C 1 240 ? -65.93  11.737  48.503  1   112.22 ? 236 TYR C CB  1 
ATOM   6400 C  CG  . TYR C 1 240 ? -67.069 12.694  48.175  1   120.29 ? 236 TYR C CG  1 
ATOM   6401 C  CD1 . TYR C 1 240 ? -68.212 12.759  48.972  1   121.87 ? 236 TYR C CD1 1 
ATOM   6402 C  CD2 . TYR C 1 240 ? -66.986 13.557  47.087  1   119.45 ? 236 TYR C CD2 1 
ATOM   6403 C  CE1 . TYR C 1 240 ? -69.245 13.638  48.685  1   123.13 ? 236 TYR C CE1 1 
ATOM   6404 C  CE2 . TYR C 1 240 ? -68.013 14.442  46.792  1   121.39 ? 236 TYR C CE2 1 
ATOM   6405 C  CZ  . TYR C 1 240 ? -69.144 14.489  47.595  1   125.95 ? 236 TYR C CZ  1 
ATOM   6406 O  OH  . TYR C 1 240 ? -70.162 15.365  47.316  1   129.16 ? 236 TYR C OH  1 
ATOM   6407 N  N   . LYS C 1 241 ? -66.117 13.814  51.045  1   119.02 ? 237 LYS C N   1 
ATOM   6408 C  CA  . LYS C 1 241 ? -66.734 14.189  52.313  1   117.93 ? 237 LYS C CA  1 
ATOM   6409 C  C   . LYS C 1 241 ? -68.01  14.988  52.048  1   121.05 ? 237 LYS C C   1 
ATOM   6410 O  O   . LYS C 1 241 ? -67.974 15.991  51.329  1   110.24 ? 237 LYS C O   1 
ATOM   6411 C  CB  . LYS C 1 241 ? -65.813 15.067  53.175  1   118.97 ? 237 LYS C CB  1 
ATOM   6412 C  CG  . LYS C 1 241 ? -64.54  14.46   53.742  1   122.3  ? 237 LYS C CG  1 
ATOM   6413 C  CD  . LYS C 1 241 ? -63.668 15.412  54.57   1   121.86 ? 237 LYS C CD  1 
ATOM   6414 C  CE  . LYS C 1 241 ? -62.406 14.855  55.175  1   117.43 ? 237 LYS C CE  1 
ATOM   6415 N  NZ  . LYS C 1 241 ? -61.569 15.785  55.947  1   104.07 ? 237 LYS C NZ  1 
ATOM   6416 N  N   . PRO C 1 242 ? -69.164 14.557  52.623  1   130.25 ? 238 PRO C N   1 
ATOM   6417 C  CA  . PRO C 1 242 ? -70.46  15.204  52.377  1   132.68 ? 238 PRO C CA  1 
ATOM   6418 C  C   . PRO C 1 242 ? -70.6   16.695  52.701  1   133.58 ? 238 PRO C C   1 
ATOM   6419 O  O   . PRO C 1 242 ? -71.533 17.342  52.219  1   130.29 ? 238 PRO C O   1 
ATOM   6420 C  CB  . PRO C 1 242 ? -71.448 14.332  53.186  1   128.46 ? 238 PRO C CB  1 
ATOM   6421 C  CG  . PRO C 1 242 ? -70.588 13.656  54.226  1   123.55 ? 238 PRO C CG  1 
ATOM   6422 C  CD  . PRO C 1 242 ? -69.265 13.403  53.537  1   121.92 ? 238 PRO C CD  1 
ATOM   6423 N  N   . SER C 1 243 ? -69.672 17.219  53.52   1   136.9  ? 239 SER C N   1 
ATOM   6424 C  CA  . SER C 1 243 ? -69.68  18.6    53.993  1   132.88 ? 239 SER C CA  1 
ATOM   6425 C  C   . SER C 1 243 ? -69.044 19.567  52.988  1   130.89 ? 239 SER C C   1 
ATOM   6426 O  O   . SER C 1 243 ? -69.139 20.778  53.176  1   144.43 ? 239 SER C O   1 
ATOM   6427 C  CB  . SER C 1 243 ? -69.021 18.712  55.345  1   121.26 ? 239 SER C CB  1 
ATOM   6428 O  OG  . SER C 1 243 ? -67.727 18.132  55.27   1   120.08 ? 239 SER C OG  1 
ATOM   6429 N  N   . PHE C 1 244 ? -68.415 19.055  51.918  1   116.27 ? 240 PHE C N   1 
ATOM   6430 C  CA  . PHE C 1 244 ? -67.771 19.923  50.938  1   111.71 ? 240 PHE C CA  1 
ATOM   6431 C  C   . PHE C 1 244 ? -68.668 21.123  50.618  1   115.91 ? 240 PHE C C   1 
ATOM   6432 O  O   . PHE C 1 244 ? -69.882 20.954  50.459  1   126.53 ? 240 PHE C O   1 
ATOM   6433 C  CB  . PHE C 1 244 ? -67.418 19.197  49.639  1   110.02 ? 240 PHE C CB  1 
ATOM   6434 C  CG  . PHE C 1 244 ? -66.199 18.281  49.685  1   116.34 ? 240 PHE C CG  1 
ATOM   6435 C  CD1 . PHE C 1 244 ? -65.051 18.611  50.408  1   122.03 ? 240 PHE C CD1 1 
ATOM   6436 C  CD2 . PHE C 1 244 ? -66.187 17.088  48.965  1   116.36 ? 240 PHE C CD2 1 
ATOM   6437 C  CE1 . PHE C 1 244 ? -63.949 17.756  50.418  1   124.01 ? 240 PHE C CE1 1 
ATOM   6438 C  CE2 . PHE C 1 244 ? -65.083 16.236  48.979  1   110.07 ? 240 PHE C CE2 1 
ATOM   6439 C  CZ  . PHE C 1 244 ? -63.958 16.578  49.691  1   110.44 ? 240 PHE C CZ  1 
ATOM   6440 N  N   . PRO C 1 245 ? -68.128 22.372  50.529  1   106.51 ? 241 PRO C N   1 
ATOM   6441 C  CA  . PRO C 1 245 ? -68.925 23.516  50.081  1   103.54 ? 241 PRO C CA  1 
ATOM   6442 C  C   . PRO C 1 245 ? -69.408 23.157  48.67   1   112.04 ? 241 PRO C C   1 
ATOM   6443 O  O   . PRO C 1 245 ? -68.757 22.375  47.98   1   113.34 ? 241 PRO C O   1 
ATOM   6444 C  CB  . PRO C 1 245 ? -67.948 24.715  50.131  1   89.98  ? 241 PRO C CB  1 
ATOM   6445 C  CG  . PRO C 1 245 ? -66.856 24.259  51.047  1   88.9   ? 241 PRO C CG  1 
ATOM   6446 C  CD  . PRO C 1 245 ? -66.735 22.76   50.807  1   93.81  ? 241 PRO C CD  1 
ATOM   6447 N  N   . LYS C 1 246 ? -70.584 23.658  48.275  1   121.59 ? 242 LYS C N   1 
ATOM   6448 C  CA  . LYS C 1 246 ? -71.14  23.428  46.947  1   119.1  ? 242 LYS C CA  1 
ATOM   6449 C  C   . LYS C 1 246 ? -70.92  24.675  46.085  1   113.67 ? 242 LYS C C   1 
ATOM   6450 O  O   . LYS C 1 246 ? -71.772 25.564  46.078  1   113.04 ? 242 LYS C O   1 
ATOM   6451 C  CB  . LYS C 1 246 ? -72.629 23.067  47.077  1   119.13 ? 242 LYS C CB  1 
ATOM   6452 C  CG  . LYS C 1 246 ? -72.971 21.74   47.746  1   122.55 ? 242 LYS C CG  1 
ATOM   6453 C  CD  . LYS C 1 246 ? -74.48  21.512  47.835  1   127.47 ? 242 LYS C CD  1 
ATOM   6454 C  CE  . LYS C 1 246 ? -74.798 20.198  48.47   1   127.96 ? 242 LYS C CE  1 
ATOM   6455 N  NZ  . LYS C 1 246 ? -76.259 20.059  48.544  1   138.8  ? 242 LYS C NZ  1 
ATOM   6456 N  N   . TRP C 1 247 ? -69.786 24.727  45.362  1   113.01 ? 243 TRP C N   1 
ATOM   6457 C  CA  . TRP C 1 247 ? -69.425 25.853  44.498  1   109.56 ? 243 TRP C CA  1 
ATOM   6458 C  C   . TRP C 1 247 ? -70.065 25.707  43.122  1   114.02 ? 243 TRP C C   1 
ATOM   6459 O  O   . TRP C 1 247 ? -70.346 24.591  42.693  1   124.23 ? 243 TRP C O   1 
ATOM   6460 C  CB  . TRP C 1 247 ? -67.901 26.002  44.338  1   93.92  ? 243 TRP C CB  1 
ATOM   6461 C  CG  . TRP C 1 247 ? -67.212 26.55   45.557  1   88.18  ? 243 TRP C CG  1 
ATOM   6462 C  CD1 . TRP C 1 247 ? -67.243 27.834  46.013  1   80.08  ? 243 TRP C CD1 1 
ATOM   6463 C  CD2 . TRP C 1 247 ? -66.387 25.798  46.478  1   83.58  ? 243 TRP C CD2 1 
ATOM   6464 N  NE1 . TRP C 1 247 ? -66.508 27.92   47.161  1   80.67  ? 243 TRP C NE1 1 
ATOM   6465 C  CE2 . TRP C 1 247 ? -65.967 26.695  47.475  1   83     ? 243 TRP C CE2 1 
ATOM   6466 C  CE3 . TRP C 1 247 ? -65.963 24.467  46.564  1   77.93  ? 243 TRP C CE3 1 
ATOM   6467 C  CZ2 . TRP C 1 247 ? -65.154 26.287  48.545  1   80.16  ? 243 TRP C CZ2 1 
ATOM   6468 C  CZ3 . TRP C 1 247 ? -65.16  24.082  47.62   1   78.39  ? 243 TRP C CZ3 1 
ATOM   6469 C  CH2 . TRP C 1 247 ? -64.744 24.974  48.607  1   74.14  ? 243 TRP C CH2 1 
ATOM   6470 N  N   . ALA C 1 248 ? -70.255 26.839  42.433  1   117.61 ? 244 ALA C N   1 
ATOM   6471 C  CA  . ALA C 1 248 ? -70.652 26.825  41.034  1   122.34 ? 244 ALA C CA  1 
ATOM   6472 C  C   . ALA C 1 248 ? -69.402 26.981  40.164  1   125.09 ? 244 ALA C C   1 
ATOM   6473 O  O   . ALA C 1 248 ? -68.407 27.548  40.621  1   127.39 ? 244 ALA C O   1 
ATOM   6474 C  CB  . ALA C 1 248 ? -71.688 27.896  40.781  1   115.77 ? 244 ALA C CB  1 
ATOM   6475 N  N   . ARG C 1 249 ? -69.455 26.436  38.935  1   118.75 ? 245 ARG C N   1 
ATOM   6476 C  CA  . ARG C 1 249 ? -68.332 26.436  38.008  1   110.95 ? 245 ARG C CA  1 
ATOM   6477 C  C   . ARG C 1 249 ? -68.12  27.858  37.5    1   116.9  ? 245 ARG C C   1 
ATOM   6478 O  O   . ARG C 1 249 ? -69.087 28.53   37.145  1   117.42 ? 245 ARG C O   1 
ATOM   6479 C  CB  . ARG C 1 249 ? -68.607 25.477  36.843  1   102.38 ? 245 ARG C CB  1 
ATOM   6480 C  CG  . ARG C 1 249 ? -67.588 25.532  35.716  1   105.92 ? 245 ARG C CG  1 
ATOM   6481 C  CD  . ARG C 1 249 ? -68.197 24.934  34.458  1   105.67 ? 245 ARG C CD  1 
ATOM   6482 N  NE  . ARG C 1 249 ? -67.23  24.458  33.461  1   105.29 ? 245 ARG C NE  1 
ATOM   6483 C  CZ  . ARG C 1 249 ? -66.795 23.197  33.41   1   98.83  ? 245 ARG C CZ  1 
ATOM   6484 N  NH1 . ARG C 1 249 ? -66.8   22.423  34.486  1   93.83  ? 245 ARG C NH1 1 
ATOM   6485 N  NH2 . ARG C 1 249 ? -66.306 22.727  32.284  1   94.86  ? 245 ARG C NH2 1 
ATOM   6486 N  N   . GLN C 1 250 ? -66.86  28.316  37.48   1   122.72 ? 246 GLN C N   1 
ATOM   6487 C  CA  . GLN C 1 250 ? -66.564 29.626  36.918  1   124.24 ? 246 GLN C CA  1 
ATOM   6488 C  C   . GLN C 1 250 ? -66.648 29.516  35.393  1   124.51 ? 246 GLN C C   1 
ATOM   6489 O  O   . GLN C 1 250 ? -66.505 28.426  34.832  1   115.28 ? 246 GLN C O   1 
ATOM   6490 C  CB  . GLN C 1 250 ? -65.204 30.167  37.361  1   119.88 ? 246 GLN C CB  1 
ATOM   6491 C  CG  . GLN C 1 250 ? -65.115 30.497  38.843  1   128.9  ? 246 GLN C CG  1 
ATOM   6492 C  CD  . GLN C 1 250 ? -63.738 30.959  39.254  1   134.55 ? 246 GLN C CD  1 
ATOM   6493 O  OE1 . GLN C 1 250 ? -62.74  30.627  38.611  1   146.05 ? 246 GLN C OE1 1 
ATOM   6494 N  NE2 . GLN C 1 250 ? -63.665 31.733  40.327  1   129.11 ? 246 GLN C NE2 1 
ATOM   6495 N  N   . ASP C 1 251 ? -66.909 30.65   34.73   1   128.38 ? 247 ASP C N   1 
ATOM   6496 C  CA  . ASP C 1 251 ? -66.96  30.682  33.279  1   126.32 ? 247 ASP C CA  1 
ATOM   6497 C  C   . ASP C 1 251 ? -65.537 30.534  32.747  1   114.81 ? 247 ASP C C   1 
ATOM   6498 O  O   . ASP C 1 251 ? -64.631 31.236  33.179  1   112.73 ? 247 ASP C O   1 
ATOM   6499 C  CB  . ASP C 1 251 ? -67.618 31.955  32.777  1   136.39 ? 247 ASP C CB  1 
ATOM   6500 C  CG  . ASP C 1 251 ? -68.483 31.803  31.544  1   139.64 ? 247 ASP C CG  1 
ATOM   6501 O  OD1 . ASP C 1 251 ? -67.99  31.216  30.555  1   141.35 ? 247 ASP C OD1 1 
ATOM   6502 O  OD2 . ASP C 1 251 ? -69.628 32.292  31.598  1   136.12 ? 247 ASP C OD2 1 
ATOM   6503 N  N   . PHE C 1 252 ? -65.353 29.621  31.79   1   110.68 ? 248 PHE C N   1 
ATOM   6504 C  CA  . PHE C 1 252 ? -64.029 29.368  31.244  1   112.32 ? 248 PHE C CA  1 
ATOM   6505 C  C   . PHE C 1 252 ? -63.459 30.635  30.605  1   113.15 ? 248 PHE C C   1 
ATOM   6506 O  O   . PHE C 1 252 ? -62.261 30.73   30.334  1   119.03 ? 248 PHE C O   1 
ATOM   6507 C  CB  . PHE C 1 252 ? -64.141 28.178  30.288  1   119.25 ? 248 PHE C CB  1 
ATOM   6508 C  CG  . PHE C 1 252 ? -63.829 26.834  30.937  1   127.85 ? 248 PHE C CG  1 
ATOM   6509 C  CD1 . PHE C 1 252 ? -64.285 26.52   32.216  1   124.05 ? 248 PHE C CD1 1 
ATOM   6510 C  CD2 . PHE C 1 252 ? -63.053 25.892  30.262  1   120.02 ? 248 PHE C CD2 1 
ATOM   6511 C  CE1 . PHE C 1 252 ? -63.981 25.291  32.789  1   121.88 ? 248 PHE C CE1 1 
ATOM   6512 C  CE2 . PHE C 1 252 ? -62.749 24.665  30.833  1   109.46 ? 248 PHE C CE2 1 
ATOM   6513 C  CZ  . PHE C 1 252 ? -63.212 24.366  32.096  1   111.32 ? 248 PHE C CZ  1 
ATOM   6514 N  N   . SER C 1 253 ? -64.342 31.607  30.364  1   117.08 ? 249 SER C N   1 
ATOM   6515 C  CA  . SER C 1 253 ? -63.979 32.89   29.78   1   118.15 ? 249 SER C CA  1 
ATOM   6516 C  C   . SER C 1 253 ? -63.309 33.759  30.846  1   118.54 ? 249 SER C C   1 
ATOM   6517 O  O   . SER C 1 253 ? -62.66  34.756  30.542  1   115.86 ? 249 SER C O   1 
ATOM   6518 C  CB  . SER C 1 253 ? -65.198 33.56   29.201  1   112.26 ? 249 SER C CB  1 
ATOM   6519 O  OG  . SER C 1 253 ? -65.672 32.771  28.12   1   105.29 ? 249 SER C OG  1 
ATOM   6520 N  N   . LYS C 1 254 ? -63.479 33.36   32.108  1   112.86 ? 250 LYS C N   1 
ATOM   6521 C  CA  . LYS C 1 254 ? -62.788 34.011  33.203  1   110.43 ? 250 LYS C CA  1 
ATOM   6522 C  C   . LYS C 1 254 ? -61.567 33.166  33.522  1   102.3  ? 250 LYS C C   1 
ATOM   6523 O  O   . LYS C 1 254 ? -60.496 33.727  33.739  1   98.78  ? 250 LYS C O   1 
ATOM   6524 C  CB  . LYS C 1 254 ? -63.663 34.113  34.456  1   119.2  ? 250 LYS C CB  1 
ATOM   6525 C  CG  . LYS C 1 254 ? -65.147 34.273  34.159  1   138.07 ? 250 LYS C CG  1 
ATOM   6526 C  CD  . LYS C 1 254 ? -66.027 34.754  35.314  1   139.56 ? 250 LYS C CD  1 
ATOM   6527 C  CE  . LYS C 1 254 ? -66.91  33.657  35.844  1   134.32 ? 250 LYS C CE  1 
ATOM   6528 N  NZ  . LYS C 1 254 ? -67.864 34.098  36.865  1   123.98 ? 250 LYS C NZ  1 
ATOM   6529 N  N   . VAL C 1 255 ? -61.762 31.834  33.515  1   100.32 ? 251 VAL C N   1 
ATOM   6530 C  CA  . VAL C 1 255 ? -60.755 30.854  33.906  1   93.97  ? 251 VAL C CA  1 
ATOM   6531 C  C   . VAL C 1 255 ? -59.552 30.952  32.975  1   91.64  ? 251 VAL C C   1 
ATOM   6532 O  O   . VAL C 1 255 ? -58.421 31.072  33.435  1   90.4   ? 251 VAL C O   1 
ATOM   6533 C  CB  . VAL C 1 255 ? -61.317 29.421  33.928  1   95.64  ? 251 VAL C CB  1 
ATOM   6534 C  CG1 . VAL C 1 255 ? -60.24  28.402  34.3    1   96.65  ? 251 VAL C CG1 1 
ATOM   6535 C  CG2 . VAL C 1 255 ? -62.534 29.315  34.846  1   92.87  ? 251 VAL C CG2 1 
ATOM   6536 N  N   . VAL C 1 256 ? -59.823 30.913  31.667  1   94.71  ? 252 VAL C N   1 
ATOM   6537 C  CA  . VAL C 1 256 ? -58.803 31.069  30.645  1   92.35  ? 252 VAL C CA  1 
ATOM   6538 C  C   . VAL C 1 256 ? -59.283 32.136  29.657  1   99.55  ? 252 VAL C C   1 
ATOM   6539 O  O   . VAL C 1 256 ? -59.727 31.84   28.548  1   98.71  ? 252 VAL C O   1 
ATOM   6540 C  CB  . VAL C 1 256 ? -58.49  29.702  30.009  1   86.17  ? 252 VAL C CB  1 
ATOM   6541 C  CG1 . VAL C 1 256 ? -57.571 29.827  28.807  1   93.94  ? 252 VAL C CG1 1 
ATOM   6542 C  CG2 . VAL C 1 256 ? -57.822 28.792  31.021  1   83.34  ? 252 VAL C CG2 1 
ATOM   6543 N  N   . PRO C 1 257 ? -59.248 33.431  30.057  1   107.15 ? 253 PRO C N   1 
ATOM   6544 C  CA  . PRO C 1 257 ? -59.747 34.517  29.209  1   101.53 ? 253 PRO C CA  1 
ATOM   6545 C  C   . PRO C 1 257 ? -59.302 34.489  27.748  1   99.96  ? 253 PRO C C   1 
ATOM   6546 O  O   . PRO C 1 257 ? -60.114 34.726  26.867  1   103.61 ? 253 PRO C O   1 
ATOM   6547 C  CB  . PRO C 1 257 ? -59.225 35.767  29.926  1   101.33 ? 253 PRO C CB  1 
ATOM   6548 C  CG  . PRO C 1 257 ? -59.178 35.367  31.378  1   102.95 ? 253 PRO C CG  1 
ATOM   6549 C  CD  . PRO C 1 257 ? -58.715 33.919  31.344  1   108.11 ? 253 PRO C CD  1 
ATOM   6550 N  N   . PRO C 1 258 ? -58.007 34.245  27.433  1   100.24 ? 254 PRO C N   1 
ATOM   6551 C  CA  . PRO C 1 258 ? -57.527 34.283  26.048  1   93.06  ? 254 PRO C CA  1 
ATOM   6552 C  C   . PRO C 1 258 ? -58.016 33.189  25.104  1   92.14  ? 254 PRO C C   1 
ATOM   6553 O  O   . PRO C 1 258 ? -57.861 33.321  23.893  1   91.98  ? 254 PRO C O   1 
ATOM   6554 C  CB  . PRO C 1 258 ? -55.997 34.202  26.215  1   87.53  ? 254 PRO C CB  1 
ATOM   6555 C  CG  . PRO C 1 258 ? -55.755 34.624  27.645  1   87.92  ? 254 PRO C CG  1 
ATOM   6556 C  CD  . PRO C 1 258 ? -56.915 33.999  28.39   1   92.94  ? 254 PRO C CD  1 
ATOM   6557 N  N   . LEU C 1 259 ? -58.565 32.097  25.65   1   95.01  ? 255 LEU C N   1 
ATOM   6558 C  CA  . LEU C 1 259 ? -58.893 30.929  24.837  1   95.36  ? 255 LEU C CA  1 
ATOM   6559 C  C   . LEU C 1 259 ? -60.209 31.164  24.109  1   99.25  ? 255 LEU C C   1 
ATOM   6560 O  O   . LEU C 1 259 ? -61.04  31.939  24.58   1   104.28 ? 255 LEU C O   1 
ATOM   6561 C  CB  . LEU C 1 259 ? -58.96  29.661  25.692  1   92.54  ? 255 LEU C CB  1 
ATOM   6562 C  CG  . LEU C 1 259 ? -58.375 28.409  25.038  1   92.54  ? 255 LEU C CG  1 
ATOM   6563 C  CD1 . LEU C 1 259 ? -57.043 28.71   24.349  1   96.88  ? 255 LEU C CD1 1 
ATOM   6564 C  CD2 . LEU C 1 259 ? -58.179 27.311  26.07   1   89.42  ? 255 LEU C CD2 1 
ATOM   6565 N  N   . ASP C 1 260 ? -60.388 30.458  22.986  1   100.47 ? 256 ASP C N   1 
ATOM   6566 C  CA  . ASP C 1 260 ? -61.577 30.556  22.153  1   104.81 ? 256 ASP C CA  1 
ATOM   6567 C  C   . ASP C 1 260 ? -62.547 29.44   22.53   1   101.46 ? 256 ASP C C   1 
ATOM   6568 O  O   . ASP C 1 260 ? -62.345 28.712  23.5    1   99.17  ? 256 ASP C O   1 
ATOM   6569 C  CB  . ASP C 1 260 ? -61.208 30.369  20.69   1   109.5  ? 256 ASP C CB  1 
ATOM   6570 C  CG  . ASP C 1 260 ? -60.262 29.199  20.456  1   113.71 ? 256 ASP C CG  1 
ATOM   6571 O  OD1 . ASP C 1 260 ? -59.151 29.219  21.039  1   109.35 ? 256 ASP C OD1 1 
ATOM   6572 O  OD2 . ASP C 1 260 ? -60.652 28.257  19.737  1   113.19 ? 256 ASP C OD2 1 
ATOM   6573 N  N   . GLU C 1 261 ? -63.553 29.251  21.677  1   97.29  ? 257 GLU C N   1 
ATOM   6574 C  CA  . GLU C 1 261 ? -64.602 28.29   21.953  1   98.85  ? 257 GLU C CA  1 
ATOM   6575 C  C   . GLU C 1 261 ? -64.093 26.854  21.783  1   99.73  ? 257 GLU C C   1 
ATOM   6576 O  O   . GLU C 1 261 ? -64.582 25.937  22.447  1   100.74 ? 257 GLU C O   1 
ATOM   6577 C  CB  . GLU C 1 261 ? -65.704 28.691  20.982  1   98.63  ? 257 GLU C CB  1 
ATOM   6578 C  CG  . GLU C 1 261 ? -67.088 28.17   21.34   1   108.06 ? 257 GLU C CG  1 
ATOM   6579 C  CD  . GLU C 1 261 ? -68.006 28.514  20.171  1   123.68 ? 257 GLU C CD  1 
ATOM   6580 O  OE1 . GLU C 1 261 ? -69.241 28.377  20.325  1   134.31 ? 257 GLU C OE1 1 
ATOM   6581 O  OE2 . GLU C 1 261 ? -67.493 28.915  19.093  1   124.16 ? 257 GLU C OE2 1 
ATOM   6582 N  N   . ASP C 1 262 ? -63.115 26.668  20.885  1   94.91  ? 258 ASP C N   1 
ATOM   6583 C  CA  . ASP C 1 262 ? -62.556 25.35   20.618  1   92.92  ? 258 ASP C CA  1 
ATOM   6584 C  C   . ASP C 1 262 ? -61.629 24.954  21.769  1   86.17  ? 258 ASP C C   1 
ATOM   6585 O  O   . ASP C 1 262 ? -61.735 23.858  22.327  1   83.17  ? 258 ASP C O   1 
ATOM   6586 C  CB  . ASP C 1 262 ? -61.859 25.298  19.26   1   94.86  ? 258 ASP C CB  1 
ATOM   6587 C  CG  . ASP C 1 262 ? -62.747 25.23   18.023  1   96.7   ? 258 ASP C CG  1 
ATOM   6588 O  OD1 . ASP C 1 262 ? -63.906 24.79   18.136  1   96.8   ? 258 ASP C OD1 1 
ATOM   6589 O  OD2 . ASP C 1 262 ? -62.273 25.641  16.949  1   96.49  ? 258 ASP C OD2 1 
ATOM   6590 N  N   . GLY C 1 263 ? -60.708 25.863  22.11   1   78.09  ? 259 GLY C N   1 
ATOM   6591 C  CA  . GLY C 1 263 ? -59.766 25.61   23.176  1   76.14  ? 259 GLY C CA  1 
ATOM   6592 C  C   . GLY C 1 263 ? -60.507 25.323  24.477  1   76.87  ? 259 GLY C C   1 
ATOM   6593 O  O   . GLY C 1 263 ? -60.121 24.438  25.246  1   81.17  ? 259 GLY C O   1 
ATOM   6594 N  N   . ARG C 1 264 ? -61.575 26.089  24.698  1   78.54  ? 260 ARG C N   1 
ATOM   6595 C  CA  . ARG C 1 264 ? -62.333 26.018  25.934  1   79.05  ? 260 ARG C CA  1 
ATOM   6596 C  C   . ARG C 1 264 ? -63.067 24.68   26.022  1   76.19  ? 260 ARG C C   1 
ATOM   6597 O  O   . ARG C 1 264 ? -63.187 24.134  27.118  1   82.29  ? 260 ARG C O   1 
ATOM   6598 C  CB  . ARG C 1 264 ? -63.202 27.272  26.09   1   86.76  ? 260 ARG C CB  1 
ATOM   6599 C  CG  . ARG C 1 264 ? -62.445 28.438  26.724  1   96.48  ? 260 ARG C CG  1 
ATOM   6600 C  CD  . ARG C 1 264 ? -62.964 29.868  26.505  1   92.45  ? 260 ARG C CD  1 
ATOM   6601 N  NE  . ARG C 1 264 ? -64.369 29.863  26.084  1   101.81 ? 260 ARG C NE  1 
ATOM   6602 C  CZ  . ARG C 1 264 ? -64.834 30.535  25.03   1   112.07 ? 260 ARG C CZ  1 
ATOM   6603 N  NH1 . ARG C 1 264 ? -64.132 31.538  24.528  1   120.48 ? 260 ARG C NH1 1 
ATOM   6604 N  NH2 . ARG C 1 264 ? -66.006 30.234  24.492  1   108.93 ? 260 ARG C NH2 1 
ATOM   6605 N  N   . SER C 1 265 ? -63.534 24.173  24.87   1   72.5   ? 261 SER C N   1 
ATOM   6606 C  CA  . SER C 1 265 ? -64.198 22.883  24.765  1   70.35  ? 261 SER C CA  1 
ATOM   6607 C  C   . SER C 1 265 ? -63.225 21.745  25.092  1   70.77  ? 261 SER C C   1 
ATOM   6608 O  O   . SER C 1 265 ? -63.536 20.827  25.862  1   67.52  ? 261 SER C O   1 
ATOM   6609 C  CB  . SER C 1 265 ? -64.791 22.717  23.39   1   69.94  ? 261 SER C CB  1 
ATOM   6610 O  OG  . SER C 1 265 ? -65.702 21.631  23.354  1   72.19  ? 261 SER C OG  1 
ATOM   6611 N  N   . LEU C 1 266 ? -62.036 21.809  24.484  1   70.19  ? 262 LEU C N   1 
ATOM   6612 C  CA  . LEU C 1 266 ? -61.014 20.804  24.712  1   72.3   ? 262 LEU C CA  1 
ATOM   6613 C  C   . LEU C 1 266 ? -60.551 20.827  26.178  1   71.61  ? 262 LEU C C   1 
ATOM   6614 O  O   . LEU C 1 266 ? -60.45  19.776  26.828  1   71.76  ? 262 LEU C O   1 
ATOM   6615 C  CB  . LEU C 1 266 ? -59.89  21.044  23.702  1   69.31  ? 262 LEU C CB  1 
ATOM   6616 C  CG  . LEU C 1 266 ? -58.683 20.108  23.819  1   64.94  ? 262 LEU C CG  1 
ATOM   6617 C  CD1 . LEU C 1 266 ? -59.103 18.655  23.653  1   60.49  ? 262 LEU C CD1 1 
ATOM   6618 C  CD2 . LEU C 1 266 ? -57.621 20.512  22.791  1   64.65  ? 262 LEU C CD2 1 
ATOM   6619 N  N   . LEU C 1 267 ? -60.313 22.036  26.706  1   69.94  ? 263 LEU C N   1 
ATOM   6620 C  CA  . LEU C 1 267 ? -59.916 22.204  28.097  1   67.26  ? 263 LEU C CA  1 
ATOM   6621 C  C   . LEU C 1 267 ? -60.887 21.499  29.05   1   64.32  ? 263 LEU C C   1 
ATOM   6622 O  O   . LEU C 1 267 ? -60.446 20.775  29.941  1   70.62  ? 263 LEU C O   1 
ATOM   6623 C  CB  . LEU C 1 267 ? -59.695 23.669  28.47   1   63.04  ? 263 LEU C CB  1 
ATOM   6624 C  CG  . LEU C 1 267 ? -59.101 23.889  29.868  1   61.05  ? 263 LEU C CG  1 
ATOM   6625 C  CD1 . LEU C 1 267 ? -57.819 23.076  30.097  1   60.42  ? 263 LEU C CD1 1 
ATOM   6626 C  CD2 . LEU C 1 267 ? -58.813 25.354  30.104  1   58     ? 263 LEU C CD2 1 
ATOM   6627 N  N   . SER C 1 268 ? -62.196 21.71   28.857  1   65.33  ? 264 SER C N   1 
ATOM   6628 C  CA  . SER C 1 268 ? -63.233 21.072  29.671  1   68.51  ? 264 SER C CA  1 
ATOM   6629 C  C   . SER C 1 268 ? -63.181 19.538  29.593  1   72.36  ? 264 SER C C   1 
ATOM   6630 O  O   . SER C 1 268 ? -63.218 18.874  30.624  1   75.23  ? 264 SER C O   1 
ATOM   6631 C  CB  . SER C 1 268 ? -64.593 21.603  29.332  1   65.66  ? 264 SER C CB  1 
ATOM   6632 O  OG  . SER C 1 268 ? -64.911 21.269  27.992  1   74.78  ? 264 SER C OG  1 
ATOM   6633 N  N   . GLN C 1 269 ? -63.1   18.986  28.37   1   71.32  ? 265 GLN C N   1 
ATOM   6634 C  CA  . GLN C 1 269 ? -63.081 17.554  28.126  1   70.72  ? 265 GLN C CA  1 
ATOM   6635 C  C   . GLN C 1 269 ? -61.797 16.93   28.67   1   72.76  ? 265 GLN C C   1 
ATOM   6636 O  O   . GLN C 1 269 ? -61.771 15.74   28.999  1   71.26  ? 265 GLN C O   1 
ATOM   6637 C  CB  . GLN C 1 269 ? -63.202 17.289  26.628  1   73.13  ? 265 GLN C CB  1 
ATOM   6638 C  CG  . GLN C 1 269 ? -64.595 17.565  26.07   1   77.32  ? 265 GLN C CG  1 
ATOM   6639 C  CD  . GLN C 1 269 ? -64.629 17.567  24.555  1   82.89  ? 265 GLN C CD  1 
ATOM   6640 O  OE1 . GLN C 1 269 ? -64.841 18.598  23.898  1   80.5   ? 265 GLN C OE1 1 
ATOM   6641 N  NE2 . GLN C 1 269 ? -64.374 16.399  23.98   1   89.19  ? 265 GLN C NE2 1 
ATOM   6642 N  N   . MET C 1 270 ? -60.739 17.747  28.79   1   70.45  ? 266 MET C N   1 
ATOM   6643 C  CA  . MET C 1 270 ? -59.51  17.281  29.424  1   65.93  ? 266 MET C CA  1 
ATOM   6644 C  C   . MET C 1 270 ? -59.629 17.304  30.947  1   63.03  ? 266 MET C C   1 
ATOM   6645 O  O   . MET C 1 270 ? -59.035 16.481  31.638  1   59.78  ? 266 MET C O   1 
ATOM   6646 C  CB  . MET C 1 270 ? -58.313 18.112  28.957  1   59.33  ? 266 MET C CB  1 
ATOM   6647 C  CG  . MET C 1 270 ? -58.005 17.83   27.52   1   57.95  ? 266 MET C CG  1 
ATOM   6648 S  SD  . MET C 1 270 ? -56.545 18.684  26.915  1   65.51  ? 266 MET C SD  1 
ATOM   6649 C  CE  . MET C 1 270 ? -55.206 17.701  27.609  1   58     ? 266 MET C CE  1 
ATOM   6650 N  N   . LEU C 1 271 ? -60.396 18.267  31.465  1   66.54  ? 267 LEU C N   1 
ATOM   6651 C  CA  . LEU C 1 271 ? -60.529 18.43   32.906  1   71.58  ? 267 LEU C CA  1 
ATOM   6652 C  C   . LEU C 1 271 ? -61.876 17.906  33.409  1   74.43  ? 267 LEU C C   1 
ATOM   6653 O  O   . LEU C 1 271 ? -62.369 18.369  34.437  1   72.46  ? 267 LEU C O   1 
ATOM   6654 C  CB  . LEU C 1 271 ? -60.345 19.901  33.283  1   73.43  ? 267 LEU C CB  1 
ATOM   6655 C  CG  . LEU C 1 271 ? -58.941 20.495  33.139  1   71.09  ? 267 LEU C CG  1 
ATOM   6656 C  CD1 . LEU C 1 271 ? -58.996 21.959  33.582  1   68.93  ? 267 LEU C CD1 1 
ATOM   6657 C  CD2 . LEU C 1 271 ? -57.858 19.705  33.89   1   64.62  ? 267 LEU C CD2 1 
ATOM   6658 N  N   . HIS C 1 272 ? -62.46  16.931  32.699  1   76.39  ? 268 HIS C N   1 
ATOM   6659 C  CA  . HIS C 1 272 ? -63.704 16.33   33.15   1   77.26  ? 268 HIS C CA  1 
ATOM   6660 C  C   . HIS C 1 272 ? -63.438 15.602  34.467  1   74.11  ? 268 HIS C C   1 
ATOM   6661 O  O   . HIS C 1 272 ? -62.369 15.027  34.661  1   67.78  ? 268 HIS C O   1 
ATOM   6662 C  CB  . HIS C 1 272 ? -64.321 15.461  32.049  1   83.95  ? 268 HIS C CB  1 
ATOM   6663 C  CG  . HIS C 1 272 ? -65.784 15.182  32.232  1   94.94  ? 268 HIS C CG  1 
ATOM   6664 N  ND1 . HIS C 1 272 ? -66.336 14.581  33.349  1   97.41  ? 268 HIS C ND1 1 
ATOM   6665 C  CD2 . HIS C 1 272 ? -66.809 15.417  31.393  1   92.66  ? 268 HIS C CD2 1 
ATOM   6666 C  CE1 . HIS C 1 272 ? -67.649 14.477  33.191  1   95.43  ? 268 HIS C CE1 1 
ATOM   6667 N  NE2 . HIS C 1 272 ? -67.96  14.978  32.011  1   98.83  ? 268 HIS C NE2 1 
ATOM   6668 N  N   . TYR C 1 273 ? -64.406 15.674  35.387  1   76.65  ? 269 TYR C N   1 
ATOM   6669 C  CA  . TYR C 1 273 ? -64.258 15.057  36.691  1   74.64  ? 269 TYR C CA  1 
ATOM   6670 C  C   . TYR C 1 273 ? -64.185 13.545  36.551  1   70.95  ? 269 TYR C C   1 
ATOM   6671 O  O   . TYR C 1 273 ? -63.291 12.922  37.096  1   67.82  ? 269 TYR C O   1 
ATOM   6672 C  CB  . TYR C 1 273 ? -65.447 15.453  37.563  1   80.66  ? 269 TYR C CB  1 
ATOM   6673 C  CG  . TYR C 1 273 ? -65.141 16.684  38.393  1   83.28  ? 269 TYR C CG  1 
ATOM   6674 C  CD1 . TYR C 1 273 ? -64.279 16.597  39.475  1   81.66  ? 269 TYR C CD1 1 
ATOM   6675 C  CD2 . TYR C 1 273 ? -65.703 17.918  38.095  1   85.96  ? 269 TYR C CD2 1 
ATOM   6676 C  CE1 . TYR C 1 273 ? -63.987 17.705  40.251  1   81.46  ? 269 TYR C CE1 1 
ATOM   6677 C  CE2 . TYR C 1 273 ? -65.426 19.032  38.874  1   84.33  ? 269 TYR C CE2 1 
ATOM   6678 C  CZ  . TYR C 1 273 ? -64.558 18.93   39.948  1   84.97  ? 269 TYR C CZ  1 
ATOM   6679 O  OH  . TYR C 1 273 ? -64.269 20.029  40.708  1   88.23  ? 269 TYR C OH  1 
ATOM   6680 N  N   . ASP C 1 274 ? -65.156 12.972  35.839  1   74.5   ? 270 ASP C N   1 
ATOM   6681 C  CA  . ASP C 1 274 ? -65.275 11.536  35.67   1   74.68  ? 270 ASP C CA  1 
ATOM   6682 C  C   . ASP C 1 274 ? -64.11  11.048  34.804  1   72.5   ? 270 ASP C C   1 
ATOM   6683 O  O   . ASP C 1 274 ? -63.998 11.433  33.642  1   72.95  ? 270 ASP C O   1 
ATOM   6684 C  CB  . ASP C 1 274 ? -66.657 11.209  35.117  1   76.11  ? 270 ASP C CB  1 
ATOM   6685 C  CG  . ASP C 1 274 ? -67.006 9.734   35.002  1   79.1   ? 270 ASP C CG  1 
ATOM   6686 O  OD1 . ASP C 1 274 ? -66.097 8.887   35.193  1   83.58  ? 270 ASP C OD1 1 
ATOM   6687 O  OD2 . ASP C 1 274 ? -68.194 9.444   34.749  1   81.6   ? 270 ASP C OD2 1 
ATOM   6688 N  N   . PRO C 1 275 ? -63.198 10.193  35.328  1   71.14  ? 271 PRO C N   1 
ATOM   6689 C  CA  . PRO C 1 275 ? -62.17  9.564   34.494  1   68.89  ? 271 PRO C CA  1 
ATOM   6690 C  C   . PRO C 1 275 ? -62.714 8.927   33.213  1   75.09  ? 271 PRO C C   1 
ATOM   6691 O  O   . PRO C 1 275 ? -62.087 9.031   32.154  1   78.69  ? 271 PRO C O   1 
ATOM   6692 C  CB  . PRO C 1 275 ? -61.561 8.522   35.435  1   66.43  ? 271 PRO C CB  1 
ATOM   6693 C  CG  . PRO C 1 275 ? -61.734 9.124   36.799  1   67.54  ? 271 PRO C CG  1 
ATOM   6694 C  CD  . PRO C 1 275 ? -63.1   9.804   36.744  1   70.15  ? 271 PRO C CD  1 
ATOM   6695 N  N   . ASN C 1 276 ? -63.899 8.303   33.311  1   74.37  ? 272 ASN C N   1 
ATOM   6696 C  CA  . ASN C 1 276 ? -64.49  7.577   32.197  1   71.46  ? 272 ASN C CA  1 
ATOM   6697 C  C   . ASN C 1 276 ? -64.981 8.52    31.104  1   70.99  ? 272 ASN C C   1 
ATOM   6698 O  O   . ASN C 1 276 ? -65.143 8.099   29.967  1   68.9   ? 272 ASN C O   1 
ATOM   6699 C  CB  . ASN C 1 276 ? -65.672 6.727   32.639  1   78.38  ? 272 ASN C CB  1 
ATOM   6700 C  CG  . ASN C 1 276 ? -65.305 5.738   33.716  1   80.99  ? 272 ASN C CG  1 
ATOM   6701 O  OD1 . ASN C 1 276 ? -64.345 4.972   33.568  1   78.27  ? 272 ASN C OD1 1 
ATOM   6702 N  ND2 . ASN C 1 276 ? -66.077 5.738   34.791  1   84.89  ? 272 ASN C ND2 1 
ATOM   6703 N  N   . LYS C 1 277 ? -65.209 9.787   31.454  1   73.48  ? 273 LYS C N   1 
ATOM   6704 C  CA  . LYS C 1 277 ? -65.797 10.735  30.523  1   74.51  ? 273 LYS C CA  1 
ATOM   6705 C  C   . LYS C 1 277 ? -64.725 11.672  29.981  1   72.21  ? 273 LYS C C   1 
ATOM   6706 O  O   . LYS C 1 277 ? -64.967 12.357  28.984  1   72.96  ? 273 LYS C O   1 
ATOM   6707 C  CB  . LYS C 1 277 ? -66.941 11.496  31.195  1   81.19  ? 273 LYS C CB  1 
ATOM   6708 C  CG  . LYS C 1 277 ? -68.192 10.683  31.487  1   97.95  ? 273 LYS C CG  1 
ATOM   6709 C  CD  . LYS C 1 277 ? -68.62  9.823   30.3    1   109.71 ? 273 LYS C CD  1 
ATOM   6710 C  CE  . LYS C 1 277 ? -68.988 8.417   30.695  1   113.24 ? 273 LYS C CE  1 
ATOM   6711 N  NZ  . LYS C 1 277 ? -68.553 7.43    29.702  1   107.5  ? 273 LYS C NZ  1 
ATOM   6712 N  N   . ARG C 1 278 ? -63.559 11.694  30.653  1   66.42  ? 274 ARG C N   1 
ATOM   6713 C  CA  . ARG C 1 278 ? -62.439 12.536  30.258  1   60.62  ? 274 ARG C CA  1 
ATOM   6714 C  C   . ARG C 1 278 ? -61.971 12.072  28.884  1   60.83  ? 274 ARG C C   1 
ATOM   6715 O  O   . ARG C 1 278 ? -61.989 10.886  28.598  1   64.92  ? 274 ARG C O   1 
ATOM   6716 C  CB  . ARG C 1 278 ? -61.321 12.484  31.307  1   56.59  ? 274 ARG C CB  1 
ATOM   6717 C  CG  . ARG C 1 278 ? -60.381 13.679  31.308  1   55.78  ? 274 ARG C CG  1 
ATOM   6718 C  CD  . ARG C 1 278 ? -59.413 13.616  32.491  1   55.38  ? 274 ARG C CD  1 
ATOM   6719 N  NE  . ARG C 1 278 ? -60.123 13.636  33.77   1   54.57  ? 274 ARG C NE  1 
ATOM   6720 C  CZ  . ARG C 1 278 ? -59.81  12.907  34.838  1   54.42  ? 274 ARG C CZ  1 
ATOM   6721 N  NH1 . ARG C 1 278 ? -58.652 12.271  34.898  1   50.59  ? 274 ARG C NH1 1 
ATOM   6722 N  NH2 . ARG C 1 278 ? -60.642 12.862  35.87   1   52.15  ? 274 ARG C NH2 1 
ATOM   6723 N  N   . ILE C 1 279 ? -61.604 13.022  28.031  1   60.72  ? 275 ILE C N   1 
ATOM   6724 C  CA  . ILE C 1 279 ? -61.204 12.729  26.672  1   62.59  ? 275 ILE C CA  1 
ATOM   6725 C  C   . ILE C 1 279 ? -59.888 11.949  26.715  1   68.6   ? 275 ILE C C   1 
ATOM   6726 O  O   . ILE C 1 279 ? -59.079 12.135  27.627  1   75.39  ? 275 ILE C O   1 
ATOM   6727 C  CB  . ILE C 1 279 ? -61.1   14.044  25.872  1   61.33  ? 275 ILE C CB  1 
ATOM   6728 C  CG1 . ILE C 1 279 ? -61.122 13.802  24.363  1   62.83  ? 275 ILE C CG1 1 
ATOM   6729 C  CG2 . ILE C 1 279 ? -59.887 14.873  26.305  1   59.5   ? 275 ILE C CG2 1 
ATOM   6730 C  CD1 . ILE C 1 279 ? -61.252 15.073  23.539  1   63     ? 275 ILE C CD1 1 
ATOM   6731 N  N   . SER C 1 280 ? -59.695 11.053  25.737  1   68.59  ? 276 SER C N   1 
ATOM   6732 C  CA  . SER C 1 280 ? -58.426 10.37   25.535  1   66.32  ? 276 SER C CA  1 
ATOM   6733 C  C   . SER C 1 280 ? -57.51  11.271  24.707  1   66.29  ? 276 SER C C   1 
ATOM   6734 O  O   . SER C 1 280 ? -57.995 12.189  24.045  1   63.61  ? 276 SER C O   1 
ATOM   6735 C  CB  . SER C 1 280 ? -58.634 9.05    24.85   1   69.76  ? 276 SER C CB  1 
ATOM   6736 O  OG  . SER C 1 280 ? -58.961 9.236   23.476  1   72.38  ? 276 SER C OG  1 
ATOM   6737 N  N   . ALA C 1 281 ? -56.195 10.997  24.748  1   65.31  ? 277 ALA C N   1 
ATOM   6738 C  CA  . ALA C 1 281 ? -55.226 11.712  23.929  1   61.16  ? 277 ALA C CA  1 
ATOM   6739 C  C   . ALA C 1 281 ? -55.563 11.52   22.452  1   66.03  ? 277 ALA C C   1 
ATOM   6740 O  O   . ALA C 1 281 ? -55.467 12.472  21.674  1   69.3   ? 277 ALA C O   1 
ATOM   6741 C  CB  . ALA C 1 281 ? -53.831 11.234  24.215  1   53.05  ? 277 ALA C CB  1 
ATOM   6742 N  N   . LYS C 1 282 ? -55.964 10.288  22.094  1   60.57  ? 278 LYS C N   1 
ATOM   6743 C  CA  . LYS C 1 282 ? -56.298 9.9     20.73   1   64.69  ? 278 LYS C CA  1 
ATOM   6744 C  C   . LYS C 1 282 ? -57.495 10.709  20.206  1   68.74  ? 278 LYS C C   1 
ATOM   6745 O  O   . LYS C 1 282 ? -57.402 11.356  19.162  1   72.61  ? 278 LYS C O   1 
ATOM   6746 C  CB  . LYS C 1 282 ? -56.521 8.385   20.709  1   63.78  ? 278 LYS C CB  1 
ATOM   6747 C  CG  . LYS C 1 282 ? -56.412 7.756   19.342  1   68.55  ? 278 LYS C CG  1 
ATOM   6748 C  CD  . LYS C 1 282 ? -56.812 6.286   19.255  1   72.5   ? 278 LYS C CD  1 
ATOM   6749 C  CE  . LYS C 1 282 ? -55.711 5.378   19.698  1   73.56  ? 278 LYS C CE  1 
ATOM   6750 N  NZ  . LYS C 1 282 ? -55.954 3.985   19.303  1   77.99  ? 278 LYS C NZ  1 
ATOM   6751 N  N   . ALA C 1 283 ? -58.619 10.677  20.937  1   68.69  ? 279 ALA C N   1 
ATOM   6752 C  CA  . ALA C 1 283 ? -59.781 11.513  20.657  1   71.2   ? 279 ALA C CA  1 
ATOM   6753 C  C   . ALA C 1 283 ? -59.393 12.988  20.549  1   74.94  ? 279 ALA C C   1 
ATOM   6754 O  O   . ALA C 1 283 ? -59.731 13.647  19.561  1   80.92  ? 279 ALA C O   1 
ATOM   6755 C  CB  . ALA C 1 283 ? -60.83  11.314  21.73   1   71.52  ? 279 ALA C CB  1 
ATOM   6756 N  N   . ALA C 1 284 ? -58.677 13.488  21.569  1   66.27  ? 280 ALA C N   1 
ATOM   6757 C  CA  . ALA C 1 284 ? -58.314 14.891  21.661  1   67.98  ? 280 ALA C CA  1 
ATOM   6758 C  C   . ALA C 1 284 ? -57.528 15.374  20.443  1   71.05  ? 280 ALA C C   1 
ATOM   6759 O  O   . ALA C 1 284 ? -57.5   16.572  20.185  1   79.52  ? 280 ALA C O   1 
ATOM   6760 C  CB  . ALA C 1 284 ? -57.555 15.153  22.942  1   66.83  ? 280 ALA C CB  1 
ATOM   6761 N  N   . LEU C 1 285 ? -56.87  14.464  19.714  1   72.84  ? 281 LEU C N   1 
ATOM   6762 C  CA  . LEU C 1 285 ? -56.092 14.813  18.527  1   73.39  ? 281 LEU C CA  1 
ATOM   6763 C  C   . LEU C 1 285 ? -57.019 15.178  17.367  1   79.9   ? 281 LEU C C   1 
ATOM   6764 O  O   . LEU C 1 285 ? -56.647 15.968  16.498  1   81.22  ? 281 LEU C O   1 
ATOM   6765 C  CB  . LEU C 1 285 ? -55.149 13.67   18.143  1   72.94  ? 281 LEU C CB  1 
ATOM   6766 C  CG  . LEU C 1 285 ? -53.903 13.482  19.021  1   69.82  ? 281 LEU C CG  1 
ATOM   6767 C  CD1 . LEU C 1 285 ? -53.283 12.106  18.825  1   64.59  ? 281 LEU C CD1 1 
ATOM   6768 C  CD2 . LEU C 1 285 ? -52.86  14.579  18.802  1   65.62  ? 281 LEU C CD2 1 
ATOM   6769 N  N   . ALA C 1 286 ? -58.219 14.581  17.361  1   80.57  ? 282 ALA C N   1 
ATOM   6770 C  CA  . ALA C 1 286 ? -59.26  14.909  16.4    1   80.31  ? 282 ALA C CA  1 
ATOM   6771 C  C   . ALA C 1 286 ? -59.929 16.255  16.71   1   82.28  ? 282 ALA C C   1 
ATOM   6772 O  O   . ALA C 1 286 ? -60.427 16.897  15.794  1   81.05  ? 282 ALA C O   1 
ATOM   6773 C  CB  . ALA C 1 286 ? -60.27  13.781  16.317  1   78.42  ? 282 ALA C CB  1 
ATOM   6774 N  N   . HIS C 1 287 ? -59.915 16.714  17.976  1   83.22  ? 283 HIS C N   1 
ATOM   6775 C  CA  . HIS C 1 287 ? -60.683 17.887  18.391  1   77.48  ? 283 HIS C CA  1 
ATOM   6776 C  C   . HIS C 1 287 ? -60.532 19.071  17.431  1   75.83  ? 283 HIS C C   1 
ATOM   6777 O  O   . HIS C 1 287 ? -59.427 19.394  17.014  1   74.95  ? 283 HIS C O   1 
ATOM   6778 C  CB  . HIS C 1 287 ? -60.357 18.307  19.827  1   69.76  ? 283 HIS C CB  1 
ATOM   6779 C  CG  . HIS C 1 287 ? -61.376 19.239  20.375  1   72.83  ? 283 HIS C CG  1 
ATOM   6780 N  ND1 . HIS C 1 287 ? -61.377 20.584  20.063  1   76.98  ? 283 HIS C ND1 1 
ATOM   6781 C  CD2 . HIS C 1 287 ? -62.44  19.042  21.166  1   74.22  ? 283 HIS C CD2 1 
ATOM   6782 C  CE1 . HIS C 1 287 ? -62.406 21.18   20.656  1   77.58  ? 283 HIS C CE1 1 
ATOM   6783 N  NE2 . HIS C 1 287 ? -63.057 20.263  21.339  1   78.87  ? 283 HIS C NE2 1 
ATOM   6784 N  N   . PRO C 1 288 ? -61.645 19.768  17.079  1   77.77  ? 284 PRO C N   1 
ATOM   6785 C  CA  . PRO C 1 288 ? -61.615 20.923  16.173  1   78.69  ? 284 PRO C CA  1 
ATOM   6786 C  C   . PRO C 1 288 ? -60.538 21.977  16.413  1   77.01  ? 284 PRO C C   1 
ATOM   6787 O  O   . PRO C 1 288 ? -60.192 22.71   15.488  1   80.73  ? 284 PRO C O   1 
ATOM   6788 C  CB  . PRO C 1 288 ? -63.022 21.538  16.367  1   78.01  ? 284 PRO C CB  1 
ATOM   6789 C  CG  . PRO C 1 288 ? -63.897 20.339  16.619  1   78.47  ? 284 PRO C CG  1 
ATOM   6790 C  CD  . PRO C 1 288 ? -63.024 19.44   17.488  1   78.08  ? 284 PRO C CD  1 
ATOM   6791 N  N   . PHE C 1 289 ? -60.051 22.084  17.655  1   71.42  ? 285 PHE C N   1 
ATOM   6792 C  CA  . PHE C 1 289 ? -59.069 23.099  18.002  1   72.39  ? 285 PHE C CA  1 
ATOM   6793 C  C   . PHE C 1 289 ? -57.804 22.96   17.144  1   75.58  ? 285 PHE C C   1 
ATOM   6794 O  O   . PHE C 1 289 ? -57.117 23.953  16.901  1   76.34  ? 285 PHE C O   1 
ATOM   6795 C  CB  . PHE C 1 289 ? -58.845 23.023  19.515  1   68.53  ? 285 PHE C CB  1 
ATOM   6796 C  CG  . PHE C 1 289 ? -57.74  23.891  20.094  1   66.91  ? 285 PHE C CG  1 
ATOM   6797 C  CD1 . PHE C 1 289 ? -57.86  25.273  20.081  1   68.26  ? 285 PHE C CD1 1 
ATOM   6798 C  CD2 . PHE C 1 289 ? -56.603 23.314  20.663  1   63.56  ? 285 PHE C CD2 1 
ATOM   6799 C  CE1 . PHE C 1 289 ? -56.87  26.066  20.631  1   67.36  ? 285 PHE C CE1 1 
ATOM   6800 C  CE2 . PHE C 1 289 ? -55.606 24.108  21.197  1   63.82  ? 285 PHE C CE2 1 
ATOM   6801 C  CZ  . PHE C 1 289 ? -55.746 25.482  21.177  1   69.29  ? 285 PHE C CZ  1 
ATOM   6802 N  N   . PHE C 1 290 ? -57.519 21.743  16.66   1   75.02  ? 286 PHE C N   1 
ATOM   6803 C  CA  . PHE C 1 290 ? -56.248 21.455  15.998  1   80.14  ? 286 PHE C CA  1 
ATOM   6804 C  C   . PHE C 1 290 ? -56.323 21.49   14.462  1   84.49  ? 286 PHE C C   1 
ATOM   6805 O  O   . PHE C 1 290 ? -55.278 21.425  13.806  1   80.7   ? 286 PHE C O   1 
ATOM   6806 C  CB  . PHE C 1 290 ? -55.646 20.136  16.491  1   70.68  ? 286 PHE C CB  1 
ATOM   6807 C  CG  . PHE C 1 290 ? -55.306 20.091  17.969  1   66.96  ? 286 PHE C CG  1 
ATOM   6808 C  CD1 . PHE C 1 290 ? -54.328 20.936  18.504  1   64.47  ? 286 PHE C CD1 1 
ATOM   6809 C  CD2 . PHE C 1 290 ? -55.928 19.16   18.802  1   64.87  ? 286 PHE C CD2 1 
ATOM   6810 C  CE1 . PHE C 1 290 ? -54.007 20.857  19.856  1   66     ? 286 PHE C CE1 1 
ATOM   6811 C  CE2 . PHE C 1 290 ? -55.597 19.083  20.154  1   64.27  ? 286 PHE C CE2 1 
ATOM   6812 C  CZ  . PHE C 1 290 ? -54.64  19.932  20.681  1   63.09  ? 286 PHE C CZ  1 
ATOM   6813 N  N   . GLN C 1 291 ? -57.531 21.594  13.89   1   88.73  ? 287 GLN C N   1 
ATOM   6814 C  CA  . GLN C 1 291 ? -57.749 21.691  12.446  1   99.4   ? 287 GLN C CA  1 
ATOM   6815 C  C   . GLN C 1 291 ? -56.716 22.557  11.713  1   91.87  ? 287 GLN C C   1 
ATOM   6816 O  O   . GLN C 1 291 ? -56.367 22.274  10.568  1   98.05  ? 287 GLN C O   1 
ATOM   6817 C  CB  . GLN C 1 291 ? -59.168 22.139  12.073  1   110.04 ? 287 GLN C CB  1 
ATOM   6818 C  CG  . GLN C 1 291 ? -60.271 21.143  12.441  1   119.41 ? 287 GLN C CG  1 
ATOM   6819 C  CD  . GLN C 1 291 ? -60.136 19.783  11.787  1   125.06 ? 287 GLN C CD  1 
ATOM   6820 O  OE1 . GLN C 1 291 ? -59.774 19.695  10.609  1   134.2  ? 287 GLN C OE1 1 
ATOM   6821 N  NE2 . GLN C 1 291 ? -60.424 18.713  12.52   1   115.89 ? 287 GLN C NE2 1 
ATOM   6822 N  N   . ASP C 1 292 ? -56.26  23.633  12.354  1   86.33  ? 288 ASP C N   1 
ATOM   6823 C  CA  . ASP C 1 292 ? -55.36  24.594  11.736  1   88.9   ? 288 ASP C CA  1 
ATOM   6824 C  C   . ASP C 1 292 ? -53.997 24.588  12.435  1   88.7   ? 288 ASP C C   1 
ATOM   6825 O  O   . ASP C 1 292 ? -53.338 25.629  12.492  1   92.38  ? 288 ASP C O   1 
ATOM   6826 C  CB  . ASP C 1 292 ? -55.957 25.994  11.798  1   92.19  ? 288 ASP C CB  1 
ATOM   6827 C  CG  . ASP C 1 292 ? -56.472 26.415  13.169  1   99.3   ? 288 ASP C CG  1 
ATOM   6828 O  OD1 . ASP C 1 292 ? -56.75  25.535  14.033  1   101.49 ? 288 ASP C OD1 1 
ATOM   6829 O  OD2 . ASP C 1 292 ? -56.574 27.625  13.383  1   104.49 ? 288 ASP C OD2 1 
ATOM   6830 N  N   . VAL C 1 293 ? -53.563 23.427  12.957  1   80.81  ? 289 VAL C N   1 
ATOM   6831 C  CA  . VAL C 1 293 ? -52.322 23.374  13.721  1   74.67  ? 289 VAL C CA  1 
ATOM   6832 C  C   . VAL C 1 293 ? -51.137 23.595  12.778  1   79.89  ? 289 VAL C C   1 
ATOM   6833 O  O   . VAL C 1 293 ? -51.062 22.977  11.714  1   83.83  ? 289 VAL C O   1 
ATOM   6834 C  CB  . VAL C 1 293 ? -52.161 22.096  14.574  1   67.54  ? 289 VAL C CB  1 
ATOM   6835 C  CG1 . VAL C 1 293 ? -52.169 20.828  13.726  1   68.31  ? 289 VAL C CG1 1 
ATOM   6836 C  CG2 . VAL C 1 293 ? -50.939 22.132  15.49   1   55.46  ? 289 VAL C CG2 1 
ATOM   6837 N  N   . THR C 1 294 ? -50.232 24.506  13.167  1   80.54  ? 290 THR C N   1 
ATOM   6838 C  CA  . THR C 1 294 ? -48.96  24.696  12.477  1   77.98  ? 290 THR C CA  1 
ATOM   6839 C  C   . THR C 1 294 ? -47.835 24.266  13.417  1   74.45  ? 290 THR C C   1 
ATOM   6840 O  O   . THR C 1 294 ? -48.117 23.819  14.517  1   77.58  ? 290 THR C O   1 
ATOM   6841 C  CB  . THR C 1 294 ? -48.808 26.128  11.946  1   75.59  ? 290 THR C CB  1 
ATOM   6842 O  OG1 . THR C 1 294 ? -48.739 27.049  13.033  1   75.1   ? 290 THR C OG1 1 
ATOM   6843 C  CG2 . THR C 1 294 ? -49.945 26.522  11.017  1   75.92  ? 290 THR C CG2 1 
ATOM   6844 N  N   . LYS C 1 295 ? -46.577 24.373  12.976  1   73.82  ? 291 LYS C N   1 
ATOM   6845 C  CA  . LYS C 1 295 ? -45.431 24.125  13.832  1   71.96  ? 291 LYS C CA  1 
ATOM   6846 C  C   . LYS C 1 295 ? -44.62  25.412  13.926  1   71.61  ? 291 LYS C C   1 
ATOM   6847 O  O   . LYS C 1 295 ? -43.569 25.515  13.303  1   76.48  ? 291 LYS C O   1 
ATOM   6848 C  CB  . LYS C 1 295 ? -44.526 23.015  13.279  1   73.21  ? 291 LYS C CB  1 
ATOM   6849 C  CG  . LYS C 1 295 ? -43.877 22.121  14.344  1   73.93  ? 291 LYS C CG  1 
ATOM   6850 C  CD  . LYS C 1 295 ? -42.37  21.953  14.176  1   72.12  ? 291 LYS C CD  1 
ATOM   6851 C  CE  . LYS C 1 295 ? -41.811 20.794  14.961  1   73.57  ? 291 LYS C CE  1 
ATOM   6852 N  NZ  . LYS C 1 295 ? -40.398 20.523  14.667  1   70.8   ? 291 LYS C NZ  1 
ATOM   6853 N  N   . PRO C 1 296 ? -45.077 26.432  14.686  1   71.84  ? 292 PRO C N   1 
ATOM   6854 C  CA  . PRO C 1 296 ? -44.28  27.654  14.885  1   71.26  ? 292 PRO C CA  1 
ATOM   6855 C  C   . PRO C 1 296 ? -42.932 27.411  15.581  1   74.4   ? 292 PRO C C   1 
ATOM   6856 O  O   . PRO C 1 296 ? -42.761 26.424  16.289  1   74.69  ? 292 PRO C O   1 
ATOM   6857 C  CB  . PRO C 1 296 ? -45.207 28.561  15.723  1   67.48  ? 292 PRO C CB  1 
ATOM   6858 C  CG  . PRO C 1 296 ? -46.595 27.936  15.602  1   71.7   ? 292 PRO C CG  1 
ATOM   6859 C  CD  . PRO C 1 296 ? -46.351 26.438  15.428  1   70.71  ? 292 PRO C CD  1 
ATOM   6860 N  N   . VAL C 1 297 ? -41.973 28.317  15.38   1   80.97  ? 293 VAL C N   1 
ATOM   6861 C  CA  . VAL C 1 297 ? -40.671 28.285  16.042  1   83.25  ? 293 VAL C CA  1 
ATOM   6862 C  C   . VAL C 1 297 ? -40.755 29.063  17.361  1   82.38  ? 293 VAL C C   1 
ATOM   6863 O  O   . VAL C 1 297 ? -41.266 30.174  17.387  1   83.67  ? 293 VAL C O   1 
ATOM   6864 C  CB  . VAL C 1 297 ? -39.547 28.829  15.13   1   76.08  ? 293 VAL C CB  1 
ATOM   6865 C  CG1 . VAL C 1 297 ? -38.201 28.921  15.834  1   71.41  ? 293 VAL C CG1 1 
ATOM   6866 C  CG2 . VAL C 1 297 ? -39.417 28.031  13.838  1   86.28  ? 293 VAL C CG2 1 
ATOM   6867 N  N   . PRO C 1 298 ? -40.252 28.535  18.502  1   83.71  ? 294 PRO C N   1 
ATOM   6868 C  CA  . PRO C 1 298 ? -40.285 29.271  19.773  1   83.93  ? 294 PRO C CA  1 
ATOM   6869 C  C   . PRO C 1 298 ? -39.585 30.629  19.664  1   86.92  ? 294 PRO C C   1 
ATOM   6870 O  O   . PRO C 1 298 ? -38.584 30.774  18.977  1   85.88  ? 294 PRO C O   1 
ATOM   6871 C  CB  . PRO C 1 298 ? -39.542 28.31   20.725  1   79.68  ? 294 PRO C CB  1 
ATOM   6872 C  CG  . PRO C 1 298 ? -38.656 27.477  19.799  1   83.96  ? 294 PRO C CG  1 
ATOM   6873 C  CD  . PRO C 1 298 ? -39.562 27.24   18.612  1   85.96  ? 294 PRO C CD  1 
ATOM   6874 N  N   . HIS C 1 299 ? -40.094 31.628  20.367  1   101    ? 295 HIS C N   1 
ATOM   6875 C  CA  . HIS C 1 299 ? -39.469 32.944  20.399  1   116.25 ? 295 HIS C CA  1 
ATOM   6876 C  C   . HIS C 1 299 ? -38.378 32.979  21.481  1   117.59 ? 295 HIS C C   1 
ATOM   6877 O  O   . HIS C 1 299 ? -38.601 33.52   22.566  1   130.88 ? 295 HIS C O   1 
ATOM   6878 C  CB  . HIS C 1 299 ? -40.574 33.992  20.594  1   136.42 ? 295 HIS C CB  1 
ATOM   6879 C  CG  . HIS C 1 299 ? -41.482 33.718  21.773  1   164.34 ? 295 HIS C CG  1 
ATOM   6880 N  ND1 . HIS C 1 299 ? -42.476 32.752  21.775  1   170.26 ? 295 HIS C ND1 1 
ATOM   6881 C  CD2 . HIS C 1 299 ? -41.52  34.277  23.011  1   164.77 ? 295 HIS C CD2 1 
ATOM   6882 C  CE1 . HIS C 1 299 ? -43.091 32.757  22.956  1   174.13 ? 295 HIS C CE1 1 
ATOM   6883 N  NE2 . HIS C 1 299 ? -42.528 33.67   23.725  1   163.75 ? 295 HIS C NE2 1 
ATOM   6884 N  N   . LEU C 1 300 ? -37.188 32.423  21.188  1   110.07 ? 296 LEU C N   1 
ATOM   6885 C  CA  . LEU C 1 300 ? -36.133 32.238  22.181  1   102.68 ? 296 LEU C CA  1 
ATOM   6886 C  C   . LEU C 1 300 ? -35.023 33.284  21.978  1   102.28 ? 296 LEU C C   1 
ATOM   6887 O  O   . LEU C 1 300 ? -33.961 33.089  22.612  1   98.45  ? 296 LEU C O   1 
ATOM   6888 C  CB  . LEU C 1 300 ? -35.558 30.817  22.144  1   98.64  ? 296 LEU C CB  1 
ATOM   6889 C  CG  . LEU C 1 300 ? -36.193 29.765  23.06   1   95.28  ? 296 LEU C CG  1 
ATOM   6890 C  CD1 . LEU C 1 300 ? -37.698 29.91   23.177  1   104.13 ? 296 LEU C CD1 1 
ATOM   6891 C  CD2 . LEU C 1 300 ? -35.85  28.353  22.595  1   88.35  ? 296 LEU C CD2 1 
ATOM   6892 N  N   . GLY D 2 1   ? -64.968 0.93    31.583  1   94.33  ? 171 GLY D N   1 
ATOM   6893 C  CA  . GLY D 2 1   ? -64.591 2.348   31.39   1   92.54  ? 171 GLY D CA  1 
ATOM   6894 C  C   . GLY D 2 1   ? -63.078 2.503   31.238  1   88.45  ? 171 GLY D C   1 
ATOM   6895 O  O   . GLY D 2 1   ? -62.409 1.589   30.753  1   87.4   ? 171 GLY D O   1 
ATOM   6896 N  N   . VAL D 2 2   ? -62.563 3.655   31.693  1   85.43  ? 172 VAL D N   1 
ATOM   6897 C  CA  . VAL D 2 2   ? -61.198 4.085   31.427  1   77.87  ? 172 VAL D CA  1 
ATOM   6898 C  C   . VAL D 2 2   ? -60.199 3.04    31.939  1   77.23  ? 172 VAL D C   1 
ATOM   6899 O  O   . VAL D 2 2   ? -59.112 2.877   31.375  1   74.31  ? 172 VAL D O   1 
ATOM   6900 C  CB  . VAL D 2 2   ? -60.946 5.5     31.98   1   74.78  ? 172 VAL D CB  1 
ATOM   6901 C  CG1 . VAL D 2 2   ? -60.78  5.52    33.5    1   75.18  ? 172 VAL D CG1 1 
ATOM   6902 C  CG2 . VAL D 2 2   ? -59.78  6.171   31.269  1   70.07  ? 172 VAL D CG2 1 
ATOM   6903 N  N   . ASN D 2 3   ? -60.611 2.296   32.978  1   77.2   ? 173 ASN D N   1 
ATOM   6904 C  CA  . ASN D 2 3   ? -59.847 1.198   33.562  1   76.02  ? 173 ASN D CA  1 
ATOM   6905 C  C   . ASN D 2 3   ? -59.613 0.064   32.556  1   73.68  ? 173 ASN D C   1 
ATOM   6906 O  O   . ASN D 2 3   ? -58.716 -0.754  32.75   1   72.34  ? 173 ASN D O   1 
ATOM   6907 C  CB  . ASN D 2 3   ? -60.496 0.718   34.859  1   79.64  ? 173 ASN D CB  1 
ATOM   6908 C  CG  . ASN D 2 3   ? -60.465 1.786   35.921  1   81.97  ? 173 ASN D CG  1 
ATOM   6909 O  OD1 . ASN D 2 3   ? -59.706 2.755   35.796  1   82.41  ? 173 ASN D OD1 1 
ATOM   6910 N  ND2 . ASN D 2 3   ? -61.265 1.618   36.963  1   86.82  ? 173 ASN D ND2 1 
ATOM   6911 N  N   . GLU D 2 4   ? -60.441 -0.006  31.505  1   79.94  ? 174 GLU D N   1 
ATOM   6912 C  CA  . GLU D 2 4   ? -60.288 -1.004  30.458  1   83.69  ? 174 GLU D CA  1 
ATOM   6913 C  C   . GLU D 2 4   ? -59.749 -0.338  29.195  1   83.06  ? 174 GLU D C   1 
ATOM   6914 O  O   . GLU D 2 4   ? -59.663 -0.979  28.151  1   80.74  ? 174 GLU D O   1 
ATOM   6915 C  CB  . GLU D 2 4   ? -61.627 -1.697  30.223  1   87.11  ? 174 GLU D CB  1 
ATOM   6916 C  CG  . GLU D 2 4   ? -62.151 -2.393  31.474  1   93.48  ? 174 GLU D CG  1 
ATOM   6917 C  CD  . GLU D 2 4   ? -63.577 -2.869  31.34   1   98.4   ? 174 GLU D CD  1 
ATOM   6918 O  OE1 . GLU D 2 4   ? -64.275 -2.43   30.394  1   98.64  ? 174 GLU D OE1 1 
ATOM   6919 O  OE2 . GLU D 2 4   ? -63.944 -3.72   32.18   1   103.99 ? 174 GLU D OE2 1 
ATOM   6920 N  N   . VAL D 2 5   ? -59.394 0.951   29.317  1   84.58  ? 175 VAL D N   1 
ATOM   6921 C  CA  . VAL D 2 5   ? -58.711 1.736   28.288  1   79.35  ? 175 VAL D CA  1 
ATOM   6922 C  C   . VAL D 2 5   ? -59.323 1.444   26.909  1   77.57  ? 175 VAL D C   1 
ATOM   6923 O  O   . VAL D 2 5   ? -58.663 0.945   25.993  1   73.22  ? 175 VAL D O   1 
ATOM   6924 C  CB  . VAL D 2 5   ? -57.169 1.577   28.346  1   71.2   ? 175 VAL D CB  1 
ATOM   6925 C  CG1 . VAL D 2 5   ? -56.567 2.286   29.549  1   62.73  ? 175 VAL D CG1 1 
ATOM   6926 C  CG2 . VAL D 2 5   ? -56.713 0.116   28.335  1   65.86  ? 175 VAL D CG2 1 
ATOM   6927 N  N   . PRO D 2 6   ? -60.64  1.708   26.741  1   81.94  ? 176 PRO D N   1 
ATOM   6928 C  CA  . PRO D 2 6   ? -61.329 1.513   25.466  1   79.5   ? 176 PRO D CA  1 
ATOM   6929 C  C   . PRO D 2 6   ? -60.631 2.04    24.217  1   80.65  ? 176 PRO D C   1 
ATOM   6930 O  O   . PRO D 2 6   ? -60.629 1.37    23.193  1   87.17  ? 176 PRO D O   1 
ATOM   6931 C  CB  . PRO D 2 6   ? -62.687 2.203   25.669  1   78.72  ? 176 PRO D CB  1 
ATOM   6932 C  CG  . PRO D 2 6   ? -62.594 2.923   26.993  1   78.57  ? 176 PRO D CG  1 
ATOM   6933 C  CD  . PRO D 2 6   ? -61.561 2.174   27.793  1   83.67  ? 176 PRO D CD  1 
ATOM   6934 N  N   . ASP D 2 7   ? -60.054 3.242   24.292  1   80.82  ? 177 ASP D N   1 
ATOM   6935 C  CA  . ASP D 2 7   ? -59.482 3.857   23.104  1   80.52  ? 177 ASP D CA  1 
ATOM   6936 C  C   . ASP D 2 7   ? -58.102 3.3     22.749  1   75.89  ? 177 ASP D C   1 
ATOM   6937 O  O   . ASP D 2 7   ? -57.525 3.796   21.783  1   75.46  ? 177 ASP D O   1 
ATOM   6938 C  CB  . ASP D 2 7   ? -59.438 5.375   23.203  1   85.9   ? 177 ASP D CB  1 
ATOM   6939 C  CG  . ASP D 2 7   ? -60.779 6.048   23.436  1   91.94  ? 177 ASP D CG  1 
ATOM   6940 O  OD1 . ASP D 2 7   ? -61.733 5.321   23.775  1   101.02 ? 177 ASP D OD1 1 
ATOM   6941 O  OD2 . ASP D 2 7   ? -60.861 7.279   23.259  1   89.35  ? 177 ASP D OD2 1 
ATOM   6942 N  N   . TYR D 2 8   ? -57.588 2.297   23.507  1   72.21  ? 178 TYR D N   1 
ATOM   6943 C  CA  . TYR D 2 8   ? -56.219 1.789   23.403  1   65.73  ? 178 TYR D CA  1 
ATOM   6944 C  C   . TYR D 2 8   ? -56.106 0.262   23.399  1   67.56  ? 178 TYR D C   1 
ATOM   6945 O  O   . TYR D 2 8   ? -55.139 -0.248  22.844  1   69.33  ? 178 TYR D O   1 
ATOM   6946 C  CB  . TYR D 2 8   ? -55.286 2.347   24.484  1   61.11  ? 178 TYR D CB  1 
ATOM   6947 C  CG  . TYR D 2 8   ? -55.164 3.853   24.372  1   61.01  ? 178 TYR D CG  1 
ATOM   6948 C  CD1 . TYR D 2 8   ? -54.443 4.445   23.344  1   60.49  ? 178 TYR D CD1 1 
ATOM   6949 C  CD2 . TYR D 2 8   ? -55.842 4.678   25.256  1   64.55  ? 178 TYR D CD2 1 
ATOM   6950 C  CE1 . TYR D 2 8   ? -54.361 5.823   23.228  1   64.07  ? 178 TYR D CE1 1 
ATOM   6951 C  CE2 . TYR D 2 8   ? -55.785 6.054   25.138  1   66.74  ? 178 TYR D CE2 1 
ATOM   6952 C  CZ  . TYR D 2 8   ? -55.046 6.634   24.123  1   67.56  ? 178 TYR D CZ  1 
ATOM   6953 O  OH  . TYR D 2 8   ? -55.021 8.007   24.077  1   70     ? 178 TYR D OH  1 
ATOM   6954 N  N   . HIS D 2 9   ? -57.039 -0.465  24.036  1   76.16  ? 179 HIS D N   1 
ATOM   6955 C  CA  . HIS D 2 9   ? -56.977 -1.924  24.208  1   80.95  ? 179 HIS D CA  1 
ATOM   6956 C  C   . HIS D 2 9   ? -56.489 -2.66   22.949  1   82.7   ? 179 HIS D C   1 
ATOM   6957 O  O   . HIS D 2 9   ? -55.695 -3.596  23.046  1   80.6   ? 179 HIS D O   1 
ATOM   6958 C  CB  . HIS D 2 9   ? -58.274 -2.519  24.791  1   80.02  ? 179 HIS D CB  1 
ATOM   6959 C  CG  . HIS D 2 9   ? -59.376 -2.777  23.804  1   94.71  ? 179 HIS D CG  1 
ATOM   6960 N  ND1 . HIS D 2 9   ? -60.51  -1.991  23.712  1   102.27 ? 179 HIS D ND1 1 
ATOM   6961 C  CD2 . HIS D 2 9   ? -59.526 -3.743  22.869  1   101.88 ? 179 HIS D CD2 1 
ATOM   6962 C  CE1 . HIS D 2 9   ? -61.299 -2.457  22.744  1   105.02 ? 179 HIS D CE1 1 
ATOM   6963 N  NE2 . HIS D 2 9   ? -60.717 -3.519  22.212  1   105.06 ? 179 HIS D NE2 1 
ATOM   6964 N  N   . GLU D 2 10  ? -56.963 -2.24   21.768  1   82.83  ? 180 GLU D N   1 
ATOM   6965 C  CA  . GLU D 2 10  ? -56.595 -2.899  20.526  1   83.21  ? 180 GLU D CA  1 
ATOM   6966 C  C   . GLU D 2 10  ? -55.125 -2.645  20.209  1   78.64  ? 180 GLU D C   1 
ATOM   6967 O  O   . GLU D 2 10  ? -54.364 -3.599  20.07   1   80.77  ? 180 GLU D O   1 
ATOM   6968 C  CB  . GLU D 2 10  ? -57.452 -2.467  19.341  1   91.64  ? 180 GLU D CB  1 
ATOM   6969 C  CG  . GLU D 2 10  ? -58.745 -3.263  19.202  1   108.75 ? 180 GLU D CG  1 
ATOM   6970 C  CD  . GLU D 2 10  ? -59.244 -3.177  17.765  1   119.95 ? 180 GLU D CD  1 
ATOM   6971 O  OE1 . GLU D 2 10  ? -58.721 -2.364  16.962  1   114.7  ? 180 GLU D OE1 1 
ATOM   6972 O  OE2 . GLU D 2 10  ? -60.161 -3.959  17.435  1   138.26 ? 180 GLU D OE2 1 
ATOM   6973 N  N   . ASP D 2 11  ? -54.742 -1.367  20.097  1   72     ? 181 ASP D N   1 
ATOM   6974 C  CA  . ASP D 2 11  ? -53.36  -0.982  19.857  1   69.55  ? 181 ASP D CA  1 
ATOM   6975 C  C   . ASP D 2 11  ? -52.414 -1.707  20.816  1   66.53  ? 181 ASP D C   1 
ATOM   6976 O  O   . ASP D 2 11  ? -51.323 -2.09   20.393  1   68.18  ? 181 ASP D O   1 
ATOM   6977 C  CB  . ASP D 2 11  ? -53.148 0.522   19.955  1   70.43  ? 181 ASP D CB  1 
ATOM   6978 C  CG  . ASP D 2 11  ? -53.69  1.355   18.801  1   77.63  ? 181 ASP D CG  1 
ATOM   6979 O  OD1 . ASP D 2 11  ? -54.269 0.745   17.866  1   76.93  ? 181 ASP D OD1 1 
ATOM   6980 O  OD2 . ASP D 2 11  ? -53.53  2.608   18.844  1   76.69  ? 181 ASP D OD2 1 
ATOM   6981 N  N   . ILE D 2 12  ? -52.843 -1.885  22.081  1   60.56  ? 182 ILE D N   1 
ATOM   6982 C  CA  . ILE D 2 12  ? -52.022 -2.438  23.152  1   62.84  ? 182 ILE D CA  1 
ATOM   6983 C  C   . ILE D 2 12  ? -51.8   -3.928  22.911  1   65.74  ? 182 ILE D C   1 
ATOM   6984 O  O   . ILE D 2 12  ? -50.668 -4.398  23.018  1   68.25  ? 182 ILE D O   1 
ATOM   6985 C  CB  . ILE D 2 12  ? -52.637 -2.185  24.545  1   61.62  ? 182 ILE D CB  1 
ATOM   6986 C  CG1 . ILE D 2 12  ? -52.424 -0.746  25.043  1   64.07  ? 182 ILE D CG1 1 
ATOM   6987 C  CG2 . ILE D 2 12  ? -52.108 -3.197  25.559  1   55.46  ? 182 ILE D CG2 1 
ATOM   6988 C  CD1 . ILE D 2 12  ? -53.24  -0.384  26.285  1   64.36  ? 182 ILE D CD1 1 
ATOM   6989 N  N   . HIS D 2 13  ? -52.896 -4.651  22.613  1   69.03  ? 183 HIS D N   1 
ATOM   6990 C  CA  . HIS D 2 13  ? -52.898 -6.066  22.244  1   65.75  ? 183 HIS D CA  1 
ATOM   6991 C  C   . HIS D 2 13  ? -51.972 -6.334  21.057  1   62.83  ? 183 HIS D C   1 
ATOM   6992 O  O   . HIS D 2 13  ? -51.083 -7.184  21.122  1   60.24  ? 183 HIS D O   1 
ATOM   6993 C  CB  . HIS D 2 13  ? -54.317 -6.557  21.938  1   62.93  ? 183 HIS D CB  1 
ATOM   6994 C  CG  . HIS D 2 13  ? -54.358 -7.973  21.478  1   67.13  ? 183 HIS D CG  1 
ATOM   6995 N  ND1 . HIS D 2 13  ? -54.338 -9.032  22.361  1   69.36  ? 183 HIS D ND1 1 
ATOM   6996 C  CD2 . HIS D 2 13  ? -54.41  -8.516  20.257  1   66.76  ? 183 HIS D CD2 1 
ATOM   6997 C  CE1 . HIS D 2 13  ? -54.367 -10.173 21.691  1   66.33  ? 183 HIS D CE1 1 
ATOM   6998 N  NE2 . HIS D 2 13  ? -54.403 -9.879  20.415  1   66.69  ? 183 HIS D NE2 1 
ATOM   6999 N  N   . THR D 2 14  ? -52.191 -5.593  19.967  1   62.32  ? 184 THR D N   1 
ATOM   7000 C  CA  . THR D 2 14  ? -51.369 -5.69   18.768  1   66.24  ? 184 THR D CA  1 
ATOM   7001 C  C   . THR D 2 14  ? -49.894 -5.573  19.142  1   70.15  ? 184 THR D C   1 
ATOM   7002 O  O   . THR D 2 14  ? -49.063 -6.332  18.645  1   75.28  ? 184 THR D O   1 
ATOM   7003 C  CB  . THR D 2 14  ? -51.74  -4.597  17.765  1   67     ? 184 THR D CB  1 
ATOM   7004 O  OG1 . THR D 2 14  ? -53.123 -4.679  17.421  1   72.55  ? 184 THR D OG1 1 
ATOM   7005 C  CG2 . THR D 2 14  ? -50.854 -4.65   16.535  1   63.4   ? 184 THR D CG2 1 
ATOM   7006 N  N   . TYR D 2 15  ? -49.586 -4.574  19.981  1   69.38  ? 185 TYR D N   1 
ATOM   7007 C  CA  . TYR D 2 15  ? -48.234 -4.28   20.419  1   61.3   ? 185 TYR D CA  1 
ATOM   7008 C  C   . TYR D 2 15  ? -47.699 -5.415  21.287  1   58.21  ? 185 TYR D C   1 
ATOM   7009 O  O   . TYR D 2 15  ? -46.541 -5.773  21.134  1   61.43  ? 185 TYR D O   1 
ATOM   7010 C  CB  . TYR D 2 15  ? -48.197 -2.946  21.171  1   61.83  ? 185 TYR D CB  1 
ATOM   7011 C  CG  . TYR D 2 15  ? -46.807 -2.622  21.696  1   64.05  ? 185 TYR D CG  1 
ATOM   7012 C  CD1 . TYR D 2 15  ? -45.775 -2.322  20.813  1   66.75  ? 185 TYR D CD1 1 
ATOM   7013 C  CD2 . TYR D 2 15  ? -46.522 -2.652  23.058  1   58.47  ? 185 TYR D CD2 1 
ATOM   7014 C  CE1 . TYR D 2 15  ? -44.498 -2.045  21.271  1   67.03  ? 185 TYR D CE1 1 
ATOM   7015 C  CE2 . TYR D 2 15  ? -45.246 -2.387  23.525  1   63.79  ? 185 TYR D CE2 1 
ATOM   7016 C  CZ  . TYR D 2 15  ? -44.233 -2.082  22.629  1   67.2   ? 185 TYR D CZ  1 
ATOM   7017 O  OH  . TYR D 2 15  ? -42.965 -1.816  23.06   1   66.72  ? 185 TYR D OH  1 
ATOM   7018 N  N   . LEU D 2 16  ? -48.515 -5.953  22.207  1   54.94  ? 186 LEU D N   1 
ATOM   7019 C  CA  . LEU D 2 16  ? -48.077 -7.044  23.069  1   54.54  ? 186 LEU D CA  1 
ATOM   7020 C  C   . LEU D 2 16  ? -47.751 -8.276  22.23   1   56.42  ? 186 LEU D C   1 
ATOM   7021 O  O   . LEU D 2 16  ? -46.79  -8.992  22.499  1   53.8   ? 186 LEU D O   1 
ATOM   7022 C  CB  . LEU D 2 16  ? -49.125 -7.367  24.127  1   52.13  ? 186 LEU D CB  1 
ATOM   7023 C  CG  . LEU D 2 16  ? -49.313 -6.291  25.198  1   58.56  ? 186 LEU D CG  1 
ATOM   7024 C  CD1 . LEU D 2 16  ? -50.434 -6.672  26.152  1   63.37  ? 186 LEU D CD1 1 
ATOM   7025 C  CD2 . LEU D 2 16  ? -48.017 -6.03   25.944  1   52.03  ? 186 LEU D CD2 1 
ATOM   7026 N  N   . ARG D 2 17  ? -48.561 -8.5    21.196  1   60.35  ? 187 ARG D N   1 
ATOM   7027 C  CA  . ARG D 2 17  ? -48.339 -9.614  20.293  1   64.72  ? 187 ARG D CA  1 
ATOM   7028 C  C   . ARG D 2 17  ? -46.943 -9.508  19.677  1   63.02  ? 187 ARG D C   1 
ATOM   7029 O  O   . ARG D 2 17  ? -46.22  -10.496 19.581  1   67.53  ? 187 ARG D O   1 
ATOM   7030 C  CB  . ARG D 2 17  ? -49.477 -9.693  19.267  1   62.78  ? 187 ARG D CB  1 
ATOM   7031 C  CG  . ARG D 2 17  ? -50.752 -10.257 19.875  1   62.15  ? 187 ARG D CG  1 
ATOM   7032 C  CD  . ARG D 2 17  ? -50.624 -11.75  20.145  1   60.21  ? 187 ARG D CD  1 
ATOM   7033 N  NE  . ARG D 2 17  ? -50.51  -12.432 18.858  1   61.11  ? 187 ARG D NE  1 
ATOM   7034 C  CZ  . ARG D 2 17  ? -51.56  -12.891 18.178  1   62.61  ? 187 ARG D CZ  1 
ATOM   7035 N  NH1 . ARG D 2 17  ? -52.781 -12.861 18.702  1   62.81  ? 187 ARG D NH1 1 
ATOM   7036 N  NH2 . ARG D 2 17  ? -51.373 -13.387 16.974  1   59.66  ? 187 ARG D NH2 1 
ATOM   7037 N  N   . GLU D 2 18  ? -46.585 -8.292  19.267  1   60.29  ? 188 GLU D N   1 
ATOM   7038 C  CA  . GLU D 2 18  ? -45.318 -8.005  18.624  1   62.22  ? 188 GLU D CA  1 
ATOM   7039 C  C   . GLU D 2 18  ? -44.192 -8.297  19.609  1   63.44  ? 188 GLU D C   1 
ATOM   7040 O  O   . GLU D 2 18  ? -43.24  -9.003  19.272  1   67.46  ? 188 GLU D O   1 
ATOM   7041 C  CB  . GLU D 2 18  ? -45.427 -6.53   18.256  1   69.82  ? 188 GLU D CB  1 
ATOM   7042 C  CG  . GLU D 2 18  ? -44.515 -6.048  17.134  1   79.82  ? 188 GLU D CG  1 
ATOM   7043 C  CD  . GLU D 2 18  ? -44.993 -4.665  16.709  1   88.6   ? 188 GLU D CD  1 
ATOM   7044 O  OE1 . GLU D 2 18  ? -46.151 -4.537  16.208  1   80.62  ? 188 GLU D OE1 1 
ATOM   7045 O  OE2 . GLU D 2 18  ? -44.202 -3.712  16.922  1   88.43  ? 188 GLU D OE2 1 
ATOM   7046 N  N   . MET D 2 19  ? -44.343 -7.786  20.836  1   59.13  ? 189 MET D N   1 
ATOM   7047 C  CA  . MET D 2 19  ? -43.278 -7.816  21.82   1   65.28  ? 189 MET D CA  1 
ATOM   7048 C  C   . MET D 2 19  ? -43.039 -9.229  22.361  1   66.9   ? 189 MET D C   1 
ATOM   7049 O  O   . MET D 2 19  ? -41.907 -9.554  22.711  1   68.62  ? 189 MET D O   1 
ATOM   7050 C  CB  . MET D 2 19  ? -43.593 -6.858  22.973  1   65.93  ? 189 MET D CB  1 
ATOM   7051 C  CG  . MET D 2 19  ? -43.604 -5.408  22.568  1   66.35  ? 189 MET D CG  1 
ATOM   7052 S  SD  . MET D 2 19  ? -41.994 -4.976  21.888  1   70.27  ? 189 MET D SD  1 
ATOM   7053 C  CE  . MET D 2 19  ? -40.928 -5.354  23.298  1   71.03  ? 189 MET D CE  1 
ATOM   7054 N  N   . GLU D 2 20  ? -44.093 -10.06  22.446  1   64.33  ? 190 GLU D N   1 
ATOM   7055 C  CA  . GLU D 2 20  ? -43.958 -11.406 22.991  1   61.51  ? 190 GLU D CA  1 
ATOM   7056 C  C   . GLU D 2 20  ? -43.086 -12.258 22.07   1   60.42  ? 190 GLU D C   1 
ATOM   7057 O  O   . GLU D 2 20  ? -42.401 -13.166 22.533  1   60.56  ? 190 GLU D O   1 
ATOM   7058 C  CB  . GLU D 2 20  ? -45.295 -12.099 23.251  1   59.93  ? 190 GLU D CB  1 
ATOM   7059 C  CG  . GLU D 2 20  ? -46.068 -12.403 21.975  1   58.84  ? 190 GLU D CG  1 
ATOM   7060 C  CD  . GLU D 2 20  ? -47.281 -13.293 22.184  1   62.39  ? 190 GLU D CD  1 
ATOM   7061 O  OE1 . GLU D 2 20  ? -47.476 -13.8   23.333  1   55.03  ? 190 GLU D OE1 1 
ATOM   7062 O  OE2 . GLU D 2 20  ? -48.028 -13.466 21.164  1   62.39  ? 190 GLU D OE2 1 
ATOM   7063 N  N   . VAL D 2 21  ? -43.107 -11.946 20.771  1   59.18  ? 191 VAL D N   1 
ATOM   7064 C  CA  . VAL D 2 21  ? -42.222 -12.575 19.802  1   59.8   ? 191 VAL D CA  1 
ATOM   7065 C  C   . VAL D 2 21  ? -40.784 -12.166 20.112  1   60.87  ? 191 VAL D C   1 
ATOM   7066 O  O   . VAL D 2 21  ? -39.924 -13.026 20.236  1   63.86  ? 191 VAL D O   1 
ATOM   7067 C  CB  . VAL D 2 21  ? -42.595 -12.273 18.334  1   59.47  ? 191 VAL D CB  1 
ATOM   7068 C  CG1 . VAL D 2 21  ? -41.516 -12.716 17.351  1   58.7   ? 191 VAL D CG1 1 
ATOM   7069 C  CG2 . VAL D 2 21  ? -43.943 -12.875 17.952  1   57.29  ? 191 VAL D CG2 1 
ATOM   7070 N  N   . LYS D 2 22  ? -40.546 -10.864 20.291  1   62.83  ? 192 LYS D N   1 
ATOM   7071 C  CA  . LYS D 2 22  ? -39.217 -10.327 20.543  1   67.08  ? 192 LYS D CA  1 
ATOM   7072 C  C   . LYS D 2 22  ? -38.639 -10.773 21.883  1   62.97  ? 192 LYS D C   1 
ATOM   7073 O  O   . LYS D 2 22  ? -37.432 -10.957 21.985  1   70.37  ? 192 LYS D O   1 
ATOM   7074 C  CB  . LYS D 2 22  ? -39.179 -8.813  20.316  1   80.62  ? 192 LYS D CB  1 
ATOM   7075 C  CG  . LYS D 2 22  ? -39.202 -8.523  18.784  1   96.86  ? 192 LYS D CG  1 
ATOM   7076 C  CD  . LYS D 2 22  ? -38.051 -7.623  18.321  1   106.54 ? 192 LYS D CD  1 
ATOM   7077 C  CE  . LYS D 2 22  ? -37.181 -8.057  17.154  1   108.76 ? 192 LYS D CE  1 
ATOM   7078 N  NZ  . LYS D 2 22  ? -37.763 -7.909  15.815  1   117.39 ? 192 LYS D NZ  1 
ATOM   7079 N  N   . CYS D 2 23  ? -39.496 -10.979 22.885  1   61.24  ? 193 CYS D N   1 
ATOM   7080 C  CA  . CYS D 2 23  ? -39.049 -11.402 24.207  1   60.63  ? 193 CYS D CA  1 
ATOM   7081 C  C   . CYS D 2 23  ? -39.056 -12.921 24.391  1   62.45  ? 193 CYS D C   1 
ATOM   7082 O  O   . CYS D 2 23  ? -38.922 -13.386 25.521  1   61.17  ? 193 CYS D O   1 
ATOM   7083 C  CB  . CYS D 2 23  ? -39.95  -10.876 25.319  1   61.97  ? 193 CYS D CB  1 
ATOM   7084 S  SG  . CYS D 2 23  ? -39.788 -9.094  25.594  1   63.05  ? 193 CYS D SG  1 
ATOM   7085 N  N   . LYS D 2 24  ? -39.207 -13.688 23.303  1   62.11  ? 194 LYS D N   1 
ATOM   7086 C  CA  . LYS D 2 24  ? -39.39  -15.124 23.425  1   63.54  ? 194 LYS D CA  1 
ATOM   7087 C  C   . LYS D 2 24  ? -38.035 -15.786 23.666  1   62.18  ? 194 LYS D C   1 
ATOM   7088 O  O   . LYS D 2 24  ? -37.066 -15.471 22.981  1   62.74  ? 194 LYS D O   1 
ATOM   7089 C  CB  . LYS D 2 24  ? -40.057 -15.7   22.17   1   68.07  ? 194 LYS D CB  1 
ATOM   7090 C  CG  . LYS D 2 24  ? -40.595 -17.117 22.332  1   68.51  ? 194 LYS D CG  1 
ATOM   7091 C  CD  . LYS D 2 24  ? -40.858 -17.816 21.011  1   77.78  ? 194 LYS D CD  1 
ATOM   7092 C  CE  . LYS D 2 24  ? -41.277 -19.242 21.23   1   84.83  ? 194 LYS D CE  1 
ATOM   7093 N  NZ  . LYS D 2 24  ? -42.014 -19.733 20.064  1   80.42  ? 194 LYS D NZ  1 
ATOM   7094 N  N   . PRO D 2 25  ? -37.929 -16.727 24.641  1   63.36  ? 195 PRO D N   1 
ATOM   7095 C  CA  . PRO D 2 25  ? -36.727 -17.557 24.817  1   57.4   ? 195 PRO D CA  1 
ATOM   7096 C  C   . PRO D 2 25  ? -36.442 -18.477 23.647  1   56.85  ? 195 PRO D C   1 
ATOM   7097 O  O   . PRO D 2 25  ? -37.347 -18.803 22.893  1   65.07  ? 195 PRO D O   1 
ATOM   7098 C  CB  . PRO D 2 25  ? -37.026 -18.425 26.025  1   56.18  ? 195 PRO D CB  1 
ATOM   7099 C  CG  . PRO D 2 25  ? -38.15  -17.711 26.719  1   59.71  ? 195 PRO D CG  1 
ATOM   7100 C  CD  . PRO D 2 25  ? -38.964 -17.02  25.647  1   60.32  ? 195 PRO D CD  1 
ATOM   7101 N  N   . LYS D 2 26  ? -35.196 -18.944 23.572  1   57.52  ? 196 LYS D N   1 
ATOM   7102 C  CA  . LYS D 2 26  ? -34.818 -19.99  22.64   1   63.93  ? 196 LYS D CA  1 
ATOM   7103 C  C   . LYS D 2 26  ? -35.485 -21.286 23.085  1   66.93  ? 196 LYS D C   1 
ATOM   7104 O  O   . LYS D 2 26  ? -35.236 -21.738 24.2    1   68.94  ? 196 LYS D O   1 
ATOM   7105 C  CB  . LYS D 2 26  ? -33.294 -20.143 22.546  1   68.01  ? 196 LYS D CB  1 
ATOM   7106 C  CG  . LYS D 2 26  ? -32.62  -19.121 21.631  1   77.55  ? 196 LYS D CG  1 
ATOM   7107 C  CD  . LYS D 2 26  ? -31.163 -18.779 21.948  1   91.55  ? 196 LYS D CD  1 
ATOM   7108 C  CE  . LYS D 2 26  ? -30.097 -19.521 21.163  1   97.84  ? 196 LYS D CE  1 
ATOM   7109 N  NZ  . LYS D 2 26  ? -29.661 -20.793 21.749  1   111.81 ? 196 LYS D NZ  1 
ATOM   7110 N  N   . VAL D 2 27  ? -36.307 -21.858 22.188  1   67.65  ? 197 VAL D N   1 
ATOM   7111 C  CA  . VAL D 2 27  ? -37.111 -23.059 22.4    1   71.85  ? 197 VAL D CA  1 
ATOM   7112 C  C   . VAL D 2 27  ? -36.271 -24.249 22.877  1   65.73  ? 197 VAL D C   1 
ATOM   7113 O  O   . VAL D 2 27  ? -36.74  -25.062 23.683  1   69.84  ? 197 VAL D O   1 
ATOM   7114 C  CB  . VAL D 2 27  ? -37.935 -23.439 21.15   1   73.78  ? 197 VAL D CB  1 
ATOM   7115 C  CG1 . VAL D 2 27  ? -38.685 -24.76  21.333  1   72.84  ? 197 VAL D CG1 1 
ATOM   7116 C  CG2 . VAL D 2 27  ? -38.879 -22.312 20.737  1   71.24  ? 197 VAL D CG2 1 
ATOM   7117 N  N   . GLY D 2 28  ? -35.051 -24.38  22.369  1   56.83  ? 198 GLY D N   1 
ATOM   7118 C  CA  . GLY D 2 28  ? -34.294 -25.562 22.737  1   68.03  ? 198 GLY D CA  1 
ATOM   7119 C  C   . GLY D 2 28  ? -33.008 -25.252 23.494  1   71.54  ? 198 GLY D C   1 
ATOM   7120 O  O   . GLY D 2 28  ? -32.009 -25.947 23.299  1   76.03  ? 198 GLY D O   1 
ATOM   7121 N  N   . TYR D 2 29  ? -33.039 -24.26  24.38   1   66.86  ? 199 TYR D N   1 
ATOM   7122 C  CA  . TYR D 2 29  ? -31.795 -23.835 25.077  1   58.77  ? 199 TYR D CA  1 
ATOM   7123 C  C   . TYR D 2 29  ? -31.34  -24.888 26.067  1   60.61  ? 199 TYR D C   1 
ATOM   7124 O  O   . TYR D 2 29  ? -30.132 -24.962 26.32   1   64.28  ? 199 TYR D O   1 
ATOM   7125 C  CB  . TYR D 2 29  ? -32.007 -22.467 25.739  1   55.76  ? 199 TYR D CB  1 
ATOM   7126 C  CG  . TYR D 2 29  ? -32.738 -22.397 27.074  1   53.61  ? 199 TYR D CG  1 
ATOM   7127 C  CD1 . TYR D 2 29  ? -32.147 -22.844 28.249  1   54.16  ? 199 TYR D CD1 1 
ATOM   7128 C  CD2 . TYR D 2 29  ? -34.004 -21.836 27.166  1   50.6   ? 199 TYR D CD2 1 
ATOM   7129 C  CE1 . TYR D 2 29  ? -32.809 -22.784 29.46   1   53.68  ? 199 TYR D CE1 1 
ATOM   7130 C  CE2 . TYR D 2 29  ? -34.672 -21.755 28.374  1   51.56  ? 199 TYR D CE2 1 
ATOM   7131 C  CZ  . TYR D 2 29  ? -34.072 -22.228 29.525  1   55.09  ? 199 TYR D CZ  1 
ATOM   7132 O  OH  . TYR D 2 29  ? -34.714 -22.155 30.723  1   56.3   ? 199 TYR D OH  1 
ATOM   7133 N  N   . MET D 2 30  ? -32.257 -25.681 26.616  1   58.68  ? 200 MET D N   1 
ATOM   7134 C  CA  . MET D 2 30  ? -31.837 -26.592 27.673  1   58.11  ? 200 MET D CA  1 
ATOM   7135 C  C   . MET D 2 30  ? -30.858 -27.671 27.17   1   63.94  ? 200 MET D C   1 
ATOM   7136 O  O   . MET D 2 30  ? -29.948 -28.085 27.897  1   62.22  ? 200 MET D O   1 
ATOM   7137 C  CB  . MET D 2 30  ? -33.062 -27.156 28.397  1   59.61  ? 200 MET D CB  1 
ATOM   7138 C  CG  . MET D 2 30  ? -32.729 -27.791 29.738  1   64.35  ? 200 MET D CG  1 
ATOM   7139 S  SD  . MET D 2 30  ? -32.238 -26.46  30.849  1   66.85  ? 200 MET D SD  1 
ATOM   7140 C  CE  . MET D 2 30  ? -33.899 -25.887 31.246  1   69.82  ? 200 MET D CE  1 
ATOM   7141 N  N   . LYS D 2 31  ? -31.006 -28.1   25.909  1   67.37  ? 201 LYS D N   1 
ATOM   7142 C  CA  . LYS D 2 31  ? -30.08  -29.075 25.35   1   71.88  ? 201 LYS D CA  1 
ATOM   7143 C  C   . LYS D 2 31  ? -28.682 -28.471 25.191  1   69.27  ? 201 LYS D C   1 
ATOM   7144 O  O   . LYS D 2 31  ? -27.684 -29.177 25.349  1   68.64  ? 201 LYS D O   1 
ATOM   7145 C  CB  . LYS D 2 31  ? -30.574 -29.625 24.009  1   79.49  ? 201 LYS D CB  1 
ATOM   7146 C  CG  . LYS D 2 31  ? -32.075 -29.748 23.806  1   87.61  ? 201 LYS D CG  1 
ATOM   7147 C  CD  . LYS D 2 31  ? -32.274 -29.595 22.297  1   94.75  ? 201 LYS D CD  1 
ATOM   7148 C  CE  . LYS D 2 31  ? -33.441 -30.305 21.687  1   101.68 ? 201 LYS D CE  1 
ATOM   7149 N  NZ  . LYS D 2 31  ? -34.718 -29.657 22.003  1   101.23 ? 201 LYS D NZ  1 
ATOM   7150 N  N   . LYS D 2 32  ? -28.616 -27.161 24.911  1   65.04  ? 202 LYS D N   1 
ATOM   7151 C  CA  . LYS D 2 32  ? -27.35  -26.461 24.764  1   65.38  ? 202 LYS D CA  1 
ATOM   7152 C  C   . LYS D 2 32  ? -26.782 -26.033 26.128  1   61.5   ? 202 LYS D C   1 
ATOM   7153 O  O   . LYS D 2 32  ? -25.682 -25.485 26.181  1   58     ? 202 LYS D O   1 
ATOM   7154 C  CB  . LYS D 2 32  ? -27.56  -25.294 23.794  1   74.05  ? 202 LYS D CB  1 
ATOM   7155 C  CG  . LYS D 2 32  ? -28.49  -25.559 22.608  1   82.84  ? 202 LYS D CG  1 
ATOM   7156 C  CD  . LYS D 2 32  ? -28.482 -24.472 21.528  1   90.34  ? 202 LYS D CD  1 
ATOM   7157 C  CE  . LYS D 2 32  ? -29.678 -24.474 20.597  1   99.25  ? 202 LYS D CE  1 
ATOM   7158 N  NZ  . LYS D 2 32  ? -30.794 -23.608 21.018  1   95.07  ? 202 LYS D NZ  1 
ATOM   7159 N  N   . GLN D 2 33  ? -27.51  -26.282 27.235  1   61.05  ? 203 GLN D N   1 
ATOM   7160 C  CA  . GLN D 2 33  ? -27.035 -26.022 28.597  1   59.22  ? 203 GLN D CA  1 
ATOM   7161 C  C   . GLN D 2 33  ? -26.408 -27.302 29.15   1   63.11  ? 203 GLN D C   1 
ATOM   7162 O  O   . GLN D 2 33  ? -27.125 -28.228 29.528  1   67.75  ? 203 GLN D O   1 
ATOM   7163 C  CB  . GLN D 2 33  ? -28.151 -25.541 29.53   1   52.25  ? 203 GLN D CB  1 
ATOM   7164 C  CG  . GLN D 2 33  ? -28.621 -24.116 29.279  1   53.5   ? 203 GLN D CG  1 
ATOM   7165 C  CD  . GLN D 2 33  ? -27.705 -23.069 29.869  1   53.93  ? 203 GLN D CD  1 
ATOM   7166 O  OE1 . GLN D 2 33  ? -26.709 -23.384 30.528  1   52.63  ? 203 GLN D OE1 1 
ATOM   7167 N  NE2 . GLN D 2 33  ? -28.038 -21.806 29.636  1   50.01  ? 203 GLN D NE2 1 
ATOM   7168 N  N   . PRO D 2 34  ? -25.057 -27.404 29.204  1   61.44  ? 204 PRO D N   1 
ATOM   7169 C  CA  . PRO D 2 34  ? -24.417 -28.679 29.522  1   62.79  ? 204 PRO D CA  1 
ATOM   7170 C  C   . PRO D 2 34  ? -24.676 -29.193 30.945  1   62.4   ? 204 PRO D C   1 
ATOM   7171 O  O   . PRO D 2 34  ? -24.768 -30.395 31.168  1   65.33  ? 204 PRO D O   1 
ATOM   7172 C  CB  . PRO D 2 34  ? -22.936 -28.385 29.187  1   60.42  ? 204 PRO D CB  1 
ATOM   7173 C  CG  . PRO D 2 34  ? -22.793 -26.886 29.448  1   63.02  ? 204 PRO D CG  1 
ATOM   7174 C  CD  . PRO D 2 34  ? -24.099 -26.312 28.95   1   59.51  ? 204 PRO D CD  1 
ATOM   7175 N  N   . ASP D 2 35  ? -24.875 -28.281 31.898  1   61.58  ? 205 ASP D N   1 
ATOM   7176 C  CA  . ASP D 2 35  ? -24.899 -28.653 33.3    1   64.62  ? 205 ASP D CA  1 
ATOM   7177 C  C   . ASP D 2 35  ? -26.294 -28.523 33.927  1   63.74  ? 205 ASP D C   1 
ATOM   7178 O  O   . ASP D 2 35  ? -26.454 -28.874 35.093  1   67.31  ? 205 ASP D O   1 
ATOM   7179 C  CB  . ASP D 2 35  ? -23.822 -27.922 34.088  1   65.92  ? 205 ASP D CB  1 
ATOM   7180 C  CG  . ASP D 2 35  ? -23.56  -28.48  35.477  1   77.64  ? 205 ASP D CG  1 
ATOM   7181 O  OD1 . ASP D 2 35  ? -23.902 -29.671 35.693  1   84.34  ? 205 ASP D OD1 1 
ATOM   7182 O  OD2 . ASP D 2 35  ? -23.051 -27.709 36.335  1   81.08  ? 205 ASP D OD2 1 
ATOM   7183 N  N   . ILE D 2 36  ? -27.303 -28.022 33.2    1   59.46  ? 206 ILE D N   1 
ATOM   7184 C  CA  . ILE D 2 36  ? -28.634 -27.877 33.789  1   58.5   ? 206 ILE D CA  1 
ATOM   7185 C  C   . ILE D 2 36  ? -29.709 -28.466 32.869  1   60.59  ? 206 ILE D C   1 
ATOM   7186 O  O   . ILE D 2 36  ? -29.507 -28.553 31.652  1   65.63  ? 206 ILE D O   1 
ATOM   7187 C  CB  . ILE D 2 36  ? -28.944 -26.425 34.224  1   60.91  ? 206 ILE D CB  1 
ATOM   7188 C  CG1 . ILE D 2 36  ? -28.985 -25.47  33.084  1   59.66  ? 206 ILE D CG1 1 
ATOM   7189 C  CG2 . ILE D 2 36  ? -27.99  -25.918 35.308  1   62.04  ? 206 ILE D CG2 1 
ATOM   7190 C  CD1 . ILE D 2 36  ? -29.406 -24.085 33.519  1   67.73  ? 206 ILE D CD1 1 
ATOM   7191 N  N   . THR D 2 37  ? -30.861 -28.844 33.469  1   56.38  ? 207 THR D N   1 
ATOM   7192 C  CA  . THR D 2 37  ? -31.914 -29.645 32.842  1   58.48  ? 207 THR D CA  1 
ATOM   7193 C  C   . THR D 2 37  ? -33.296 -29.034 33.072  1   60.44  ? 207 THR D C   1 
ATOM   7194 O  O   . THR D 2 37  ? -33.458 -28.196 33.942  1   57.92  ? 207 THR D O   1 
ATOM   7195 C  CB  . THR D 2 37  ? -31.902 -31.077 33.391  1   59.13  ? 207 THR D CB  1 
ATOM   7196 O  OG1 . THR D 2 37  ? -32.3   -30.995 34.762  1   61.45  ? 207 THR D OG1 1 
ATOM   7197 C  CG2 . THR D 2 37  ? -30.569 -31.78  33.18   1   54.03  ? 207 THR D CG2 1 
ATOM   7198 N  N   . ASN D 2 38  ? -34.307 -29.532 32.342  1   70.56  ? 208 ASN D N   1 
ATOM   7199 C  CA  . ASN D 2 38  ? -35.687 -29.074 32.45   1   70.64  ? 208 ASN D CA  1 
ATOM   7200 C  C   . ASN D 2 38  ? -36.197 -29.271 33.883  1   71.52  ? 208 ASN D C   1 
ATOM   7201 O  O   . ASN D 2 38  ? -37.01  -28.474 34.352  1   67.09  ? 208 ASN D O   1 
ATOM   7202 C  CB  . ASN D 2 38  ? -36.592 -29.775 31.431  1   72.79  ? 208 ASN D CB  1 
ATOM   7203 C  CG  . ASN D 2 38  ? -36.498 -29.285 29.999  1   70.04  ? 208 ASN D CG  1 
ATOM   7204 O  OD1 . ASN D 2 38  ? -36.097 -28.145 29.717  1   63.87  ? 208 ASN D OD1 1 
ATOM   7205 N  ND2 . ASN D 2 38  ? -36.954 -30.123 29.08   1   69.26  ? 208 ASN D ND2 1 
ATOM   7206 N  N   . SER D 2 39  ? -35.729 -30.349 34.549  1   72.87  ? 209 SER D N   1 
ATOM   7207 C  CA  . SER D 2 39  ? -36.13  -30.77  35.889  1   68.32  ? 209 SER D CA  1 
ATOM   7208 C  C   . SER D 2 39  ? -35.605 -29.803 36.942  1   67.33  ? 209 SER D C   1 
ATOM   7209 O  O   . SER D 2 39  ? -36.309 -29.47  37.897  1   65.42  ? 209 SER D O   1 
ATOM   7210 C  CB  . SER D 2 39  ? -35.62  -32.155 36.187  1   68.79  ? 209 SER D CB  1 
ATOM   7211 O  OG  . SER D 2 39  ? -35.746 -32.457 37.571  1   69.26  ? 209 SER D OG  1 
ATOM   7212 N  N   . MET D 2 40  ? -34.338 -29.412 36.78   1   67.25  ? 210 MET D N   1 
ATOM   7213 C  CA  . MET D 2 40  ? -33.709 -28.422 37.643  1   65.53  ? 210 MET D CA  1 
ATOM   7214 C  C   . MET D 2 40  ? -34.46  -27.101 37.549  1   61.12  ? 210 MET D C   1 
ATOM   7215 O  O   . MET D 2 40  ? -34.647 -26.439 38.562  1   60.82  ? 210 MET D O   1 
ATOM   7216 C  CB  . MET D 2 40  ? -32.251 -28.174 37.253  1   56.94  ? 210 MET D CB  1 
ATOM   7217 C  CG  . MET D 2 40  ? -31.368 -29.301 37.653  1   55.97  ? 210 MET D CG  1 
ATOM   7218 S  SD  . MET D 2 40  ? -29.736 -28.959 36.985  1   56.5   ? 210 MET D SD  1 
ATOM   7219 C  CE  . MET D 2 40  ? -29     -30.604 37.096  1   52.45  ? 210 MET D CE  1 
ATOM   7220 N  N   . ARG D 2 41  ? -34.871 -26.743 36.328  1   54.67  ? 211 ARG D N   1 
ATOM   7221 C  CA  . ARG D 2 41  ? -35.561 -25.494 36.068  1   54.13  ? 211 ARG D CA  1 
ATOM   7222 C  C   . ARG D 2 41  ? -36.922 -25.531 36.759  1   55.42  ? 211 ARG D C   1 
ATOM   7223 O  O   . ARG D 2 41  ? -37.34  -24.505 37.302  1   52.36  ? 211 ARG D O   1 
ATOM   7224 C  CB  . ARG D 2 41  ? -35.665 -25.246 34.556  1   52.53  ? 211 ARG D CB  1 
ATOM   7225 C  CG  . ARG D 2 41  ? -36.492 -24.034 34.151  1   50.1   ? 211 ARG D CG  1 
ATOM   7226 C  CD  . ARG D 2 41  ? -36.739 -23.98  32.658  1   52.78  ? 211 ARG D CD  1 
ATOM   7227 N  NE  . ARG D 2 41  ? -37.668 -22.912 32.273  1   55.64  ? 211 ARG D NE  1 
ATOM   7228 C  CZ  . ARG D 2 41  ? -38.953 -22.855 32.623  1   53.94  ? 211 ARG D CZ  1 
ATOM   7229 N  NH1 . ARG D 2 41  ? -39.495 -23.841 33.317  1   48.24  ? 211 ARG D NH1 1 
ATOM   7230 N  NH2 . ARG D 2 41  ? -39.683 -21.804 32.287  1   49.15  ? 211 ARG D NH2 1 
ATOM   7231 N  N   . ALA D 2 42  ? -37.592 -26.7   36.689  1   53.56  ? 212 ALA D N   1 
ATOM   7232 C  CA  . ALA D 2 42  ? -38.876 -26.94  37.331  1   56.37  ? 212 ALA D CA  1 
ATOM   7233 C  C   . ALA D 2 42  ? -38.775 -26.727 38.842  1   59.62  ? 212 ALA D C   1 
ATOM   7234 O  O   . ALA D 2 42  ? -39.68  -26.138 39.449  1   67.36  ? 212 ALA D O   1 
ATOM   7235 C  CB  . ALA D 2 42  ? -39.401 -28.32  37.006  1   54.57  ? 212 ALA D CB  1 
ATOM   7236 N  N   . ILE D 2 43  ? -37.69  -27.217 39.451  1   55.42  ? 213 ILE D N   1 
ATOM   7237 C  CA  . ILE D 2 43  ? -37.455 -26.963 40.867  1   55.38  ? 213 ILE D CA  1 
ATOM   7238 C  C   . ILE D 2 43  ? -37.339 -25.451 41.134  1   54.33  ? 213 ILE D C   1 
ATOM   7239 O  O   . ILE D 2 43  ? -37.937 -24.931 42.079  1   54.61  ? 213 ILE D O   1 
ATOM   7240 C  CB  . ILE D 2 43  ? -36.209 -27.732 41.33   1   52.61  ? 213 ILE D CB  1 
ATOM   7241 C  CG1 . ILE D 2 43  ? -36.472 -29.209 41.427  1   52.25  ? 213 ILE D CG1 1 
ATOM   7242 C  CG2 . ILE D 2 43  ? -35.65  -27.152 42.63   1   54.99  ? 213 ILE D CG2 1 
ATOM   7243 C  CD1 . ILE D 2 43  ? -35.213 -29.995 41.703  1   51.82  ? 213 ILE D CD1 1 
ATOM   7244 N  N   . LEU D 2 44  ? -36.576 -24.755 40.284  1   50.29  ? 214 LEU D N   1 
ATOM   7245 C  CA  . LEU D 2 44  ? -36.334 -23.333 40.411  1   50.7   ? 214 LEU D CA  1 
ATOM   7246 C  C   . LEU D 2 44  ? -37.659 -22.581 40.356  1   54.19  ? 214 LEU D C   1 
ATOM   7247 O  O   . LEU D 2 44  ? -37.954 -21.784 41.248  1   57.24  ? 214 LEU D O   1 
ATOM   7248 C  CB  . LEU D 2 44  ? -35.374 -22.842 39.335  1   48.38  ? 214 LEU D CB  1 
ATOM   7249 C  CG  . LEU D 2 44  ? -35.162 -21.323 39.314  1   50.07  ? 214 LEU D CG  1 
ATOM   7250 C  CD1 . LEU D 2 44  ? -34.559 -20.86  40.631  1   48.58  ? 214 LEU D CD1 1 
ATOM   7251 C  CD2 . LEU D 2 44  ? -34.275 -20.939 38.146  1   48.43  ? 214 LEU D CD2 1 
ATOM   7252 N  N   . VAL D 2 45  ? -38.451 -22.839 39.308  1   54.36  ? 215 VAL D N   1 
ATOM   7253 C  CA  . VAL D 2 45  ? -39.719 -22.139 39.148  1   55.04  ? 215 VAL D CA  1 
ATOM   7254 C  C   . VAL D 2 45  ? -40.657 -22.45  40.319  1   56.87  ? 215 VAL D C   1 
ATOM   7255 O  O   . VAL D 2 45  ? -41.378 -21.571 40.778  1   57.08  ? 215 VAL D O   1 
ATOM   7256 C  CB  . VAL D 2 45  ? -40.385 -22.41  37.787  1   50.86  ? 215 VAL D CB  1 
ATOM   7257 C  CG1 . VAL D 2 45  ? -41.712 -21.662 37.629  1   47.48  ? 215 VAL D CG1 1 
ATOM   7258 C  CG2 . VAL D 2 45  ? -39.439 -22.058 36.652  1   48.83  ? 215 VAL D CG2 1 
ATOM   7259 N  N   . ASP D 2 46  ? -40.664 -23.703 40.788  1   58.04  ? 216 ASP D N   1 
ATOM   7260 C  CA  . ASP D 2 46  ? -41.564 -24.11  41.857  1   57.53  ? 216 ASP D CA  1 
ATOM   7261 C  C   . ASP D 2 46  ? -41.21  -23.355 43.131  1   57.67  ? 216 ASP D C   1 
ATOM   7262 O  O   . ASP D 2 46  ? -42.096 -22.975 43.886  1   59.17  ? 216 ASP D O   1 
ATOM   7263 C  CB  . ASP D 2 46  ? -41.438 -25.585 42.172  1   55.55  ? 216 ASP D CB  1 
ATOM   7264 C  CG  . ASP D 2 46  ? -42.501 -26.09  43.128  1   60.68  ? 216 ASP D CG  1 
ATOM   7265 O  OD1 . ASP D 2 46  ? -43.632 -26.34  42.654  1   61.18  ? 216 ASP D OD1 1 
ATOM   7266 O  OD2 . ASP D 2 46  ? -42.195 -26.204 44.339  1   62.06  ? 216 ASP D OD2 1 
ATOM   7267 N  N   . TRP D 2 47  ? -39.902 -23.19  43.368  1   59.01  ? 217 TRP D N   1 
ATOM   7268 C  CA  . TRP D 2 47  ? -39.375 -22.412 44.475  1   60.02  ? 217 TRP D CA  1 
ATOM   7269 C  C   . TRP D 2 47  ? -39.794 -20.94  44.363  1   62.91  ? 217 TRP D C   1 
ATOM   7270 O  O   . TRP D 2 47  ? -40.18  -20.338 45.359  1   62.21  ? 217 TRP D O   1 
ATOM   7271 C  CB  . TRP D 2 47  ? -37.85  -22.564 44.549  1   54.45  ? 217 TRP D CB  1 
ATOM   7272 C  CG  . TRP D 2 47  ? -37.204 -21.687 45.596  1   59.19  ? 217 TRP D CG  1 
ATOM   7273 C  CD1 . TRP D 2 47  ? -37.285 -21.855 46.947  1   58.47  ? 217 TRP D CD1 1 
ATOM   7274 C  CD2 . TRP D 2 47  ? -36.346 -20.536 45.39   1   55.28  ? 217 TRP D CD2 1 
ATOM   7275 N  NE1 . TRP D 2 47  ? -36.555 -20.892 47.59   1   59.6   ? 217 TRP D NE1 1 
ATOM   7276 C  CE2 . TRP D 2 47  ? -35.959 -20.076 46.666  1   57.68  ? 217 TRP D CE2 1 
ATOM   7277 C  CE3 . TRP D 2 47  ? -35.854 -19.869 44.267  1   53.5   ? 217 TRP D CE3 1 
ATOM   7278 C  CZ2 . TRP D 2 47  ? -35.122 -18.979 46.849  1   57.18  ? 217 TRP D CZ2 1 
ATOM   7279 C  CZ3 . TRP D 2 47  ? -35.036 -18.777 44.449  1   59.8   ? 217 TRP D CZ3 1 
ATOM   7280 C  CH2 . TRP D 2 47  ? -34.667 -18.342 45.723  1   57.56  ? 217 TRP D CH2 1 
ATOM   7281 N  N   . LEU D 2 48  ? -39.727 -20.36  43.154  1   56.92  ? 218 LEU D N   1 
ATOM   7282 C  CA  . LEU D 2 48  ? -40.127 -18.981 42.945  1   52.34  ? 218 LEU D CA  1 
ATOM   7283 C  C   . LEU D 2 48  ? -41.618 -18.796 43.249  1   58.02  ? 218 LEU D C   1 
ATOM   7284 O  O   . LEU D 2 48  ? -42.038 -17.727 43.676  1   53.68  ? 218 LEU D O   1 
ATOM   7285 C  CB  . LEU D 2 48  ? -39.753 -18.558 41.53   1   49.73  ? 218 LEU D CB  1 
ATOM   7286 C  CG  . LEU D 2 48  ? -38.271 -18.222 41.327  1   52.18  ? 218 LEU D CG  1 
ATOM   7287 C  CD1 . LEU D 2 48  ? -37.995 -17.696 39.926  1   49.31  ? 218 LEU D CD1 1 
ATOM   7288 C  CD2 . LEU D 2 48  ? -37.788 -17.212 42.365  1   49.99  ? 218 LEU D CD2 1 
ATOM   7289 N  N   . VAL D 2 49  ? -42.421 -19.846 43.052  1   59.81  ? 219 VAL D N   1 
ATOM   7290 C  CA  . VAL D 2 49  ? -43.839 -19.803 43.361  1   59.06  ? 219 VAL D CA  1 
ATOM   7291 C  C   . VAL D 2 49  ? -44.008 -19.655 44.87   1   59.69  ? 219 VAL D C   1 
ATOM   7292 O  O   . VAL D 2 49  ? -44.737 -18.773 45.312  1   61.24  ? 219 VAL D O   1 
ATOM   7293 C  CB  . VAL D 2 49  ? -44.586 -21.031 42.791  1   61.79  ? 219 VAL D CB  1 
ATOM   7294 C  CG1 . VAL D 2 49  ? -46.018 -21.181 43.328  1   58.78  ? 219 VAL D CG1 1 
ATOM   7295 C  CG2 . VAL D 2 49  ? -44.578 -20.994 41.271  1   57.01  ? 219 VAL D CG2 1 
ATOM   7296 N  N   . GLU D 2 50  ? -43.31  -20.5   45.64   1   59.48  ? 220 GLU D N   1 
ATOM   7297 C  CA  . GLU D 2 50  ? -43.304 -20.425 47.094  1   64.98  ? 220 GLU D CA  1 
ATOM   7298 C  C   . GLU D 2 50  ? -42.906 -19.023 47.536  1   60.68  ? 220 GLU D C   1 
ATOM   7299 O  O   . GLU D 2 50  ? -43.65  -18.388 48.26   1   58.2   ? 220 GLU D O   1 
ATOM   7300 C  CB  . GLU D 2 50  ? -42.352 -21.435 47.735  1   71.9   ? 220 GLU D CB  1 
ATOM   7301 C  CG  . GLU D 2 50  ? -42.842 -22.878 47.67   1   83.29  ? 220 GLU D CG  1 
ATOM   7302 C  CD  . GLU D 2 50  ? -42.042 -23.796 48.576  1   95.86  ? 220 GLU D CD  1 
ATOM   7303 O  OE1 . GLU D 2 50  ? -42.618 -24.78  49.106  1   102.04 ? 220 GLU D OE1 1 
ATOM   7304 O  OE2 . GLU D 2 50  ? -40.843 -23.492 48.782  1   93.79  ? 220 GLU D OE2 1 
ATOM   7305 N  N   . VAL D 2 51  ? -41.741 -18.552 47.071  1   59.55  ? 221 VAL D N   1 
ATOM   7306 C  CA  . VAL D 2 51  ? -41.239 -17.213 47.35   1   57.68  ? 221 VAL D CA  1 
ATOM   7307 C  C   . VAL D 2 51  ? -42.322 -16.162 47.1    1   59.66  ? 221 VAL D C   1 
ATOM   7308 O  O   . VAL D 2 51  ? -42.528 -15.294 47.941  1   60.72  ? 221 VAL D O   1 
ATOM   7309 C  CB  . VAL D 2 51  ? -39.918 -16.932 46.606  1   50     ? 221 VAL D CB  1 
ATOM   7310 C  CG1 . VAL D 2 51  ? -39.513 -15.466 46.639  1   44.3   ? 221 VAL D CG1 1 
ATOM   7311 C  CG2 . VAL D 2 51  ? -38.803 -17.781 47.192  1   48.69  ? 221 VAL D CG2 1 
ATOM   7312 N  N   . GLY D 2 52  ? -43.044 -16.278 45.977  1   57.03  ? 222 GLY D N   1 
ATOM   7313 C  CA  . GLY D 2 52  ? -44.11  -15.349 45.636  1   58.23  ? 222 GLY D CA  1 
ATOM   7314 C  C   . GLY D 2 52  ? -45.241 -15.325 46.671  1   66.55  ? 222 GLY D C   1 
ATOM   7315 O  O   . GLY D 2 52  ? -45.885 -14.282 46.813  1   64.58  ? 222 GLY D O   1 
ATOM   7316 N  N   . GLU D 2 53  ? -45.484 -16.465 47.356  1   68.51  ? 223 GLU D N   1 
ATOM   7317 C  CA  . GLU D 2 53  ? -46.561 -16.64  48.326  1   69.56  ? 223 GLU D CA  1 
ATOM   7318 C  C   . GLU D 2 53  ? -46.112 -16.098 49.678  1   65.21  ? 223 GLU D C   1 
ATOM   7319 O  O   . GLU D 2 53  ? -46.875 -15.398 50.327  1   68.98  ? 223 GLU D O   1 
ATOM   7320 C  CB  . GLU D 2 53  ? -47.053 -18.092 48.416  1   72.05  ? 223 GLU D CB  1 
ATOM   7321 C  CG  . GLU D 2 53  ? -47.713 -18.603 47.133  1   82.47  ? 223 GLU D CG  1 
ATOM   7322 C  CD  . GLU D 2 53  ? -48.915 -17.777 46.677  1   90.41  ? 223 GLU D CD  1 
ATOM   7323 O  OE1 . GLU D 2 53  ? -49.712 -17.355 47.568  1   81.22  ? 223 GLU D OE1 1 
ATOM   7324 O  OE2 . GLU D 2 53  ? -49.085 -17.589 45.429  1   95.58  ? 223 GLU D OE2 1 
ATOM   7325 N  N   . GLU D 2 54  ? -44.87  -16.402 50.07   1   62.45  ? 224 GLU D N   1 
ATOM   7326 C  CA  . GLU D 2 54  ? -44.279 -15.958 51.326  1   63.06  ? 224 GLU D CA  1 
ATOM   7327 C  C   . GLU D 2 54  ? -44.15  -14.43  51.373  1   61.86  ? 224 GLU D C   1 
ATOM   7328 O  O   . GLU D 2 54  ? -44.128 -13.86  52.455  1   66.16  ? 224 GLU D O   1 
ATOM   7329 C  CB  . GLU D 2 54  ? -42.927 -16.671 51.433  1   67.32  ? 224 GLU D CB  1 
ATOM   7330 C  CG  . GLU D 2 54  ? -41.961 -16.169 52.502  1   70.46  ? 224 GLU D CG  1 
ATOM   7331 C  CD  . GLU D 2 54  ? -42.254 -16.689 53.888  1   85.17  ? 224 GLU D CD  1 
ATOM   7332 O  OE1 . GLU D 2 54  ? -43.231 -17.455 54.033  1   94.1   ? 224 GLU D OE1 1 
ATOM   7333 O  OE2 . GLU D 2 54  ? -41.497 -16.346 54.821  1   92.47  ? 224 GLU D OE2 1 
ATOM   7334 N  N   . TYR D 2 55  ? -44.034 -13.762 50.22   1   57.99  ? 225 TYR D N   1 
ATOM   7335 C  CA  . TYR D 2 55  ? -43.797 -12.324 50.184  1   59.83  ? 225 TYR D CA  1 
ATOM   7336 C  C   . TYR D 2 55  ? -45.036 -11.604 49.654  1   63.61  ? 225 TYR D C   1 
ATOM   7337 O  O   . TYR D 2 55  ? -45.058 -10.379 49.558  1   64.74  ? 225 TYR D O   1 
ATOM   7338 C  CB  . TYR D 2 55  ? -42.468 -12.033 49.472  1   57.37  ? 225 TYR D CB  1 
ATOM   7339 C  CG  . TYR D 2 55  ? -41.25  -12.312 50.34   1   58.71  ? 225 TYR D CG  1 
ATOM   7340 C  CD1 . TYR D 2 55  ? -40.799 -11.37  51.258  1   60.53  ? 225 TYR D CD1 1 
ATOM   7341 C  CD2 . TYR D 2 55  ? -40.609 -13.545 50.304  1   59.9   ? 225 TYR D CD2 1 
ATOM   7342 C  CE1 . TYR D 2 55  ? -39.73  -11.639 52.105  1   64.42  ? 225 TYR D CE1 1 
ATOM   7343 C  CE2 . TYR D 2 55  ? -39.526 -13.815 51.127  1   63.3   ? 225 TYR D CE2 1 
ATOM   7344 C  CZ  . TYR D 2 55  ? -39.086 -12.863 52.037  1   63.32  ? 225 TYR D CZ  1 
ATOM   7345 O  OH  . TYR D 2 55  ? -38.001 -13.093 52.837  1   59.41  ? 225 TYR D OH  1 
ATOM   7346 N  N   . LYS D 2 56  ? -46.078 -12.394 49.358  1   66.99  ? 226 LYS D N   1 
ATOM   7347 C  CA  . LYS D 2 56  ? -47.372 -11.938 48.856  1   69.8   ? 226 LYS D CA  1 
ATOM   7348 C  C   . LYS D 2 56  ? -47.151 -11.056 47.625  1   61.77  ? 226 LYS D C   1 
ATOM   7349 O  O   . LYS D 2 56  ? -47.721 -9.974  47.531  1   63.66  ? 226 LYS D O   1 
ATOM   7350 C  CB  . LYS D 2 56  ? -48.254 -11.294 49.945  1   75.47  ? 226 LYS D CB  1 
ATOM   7351 C  CG  . LYS D 2 56  ? -48.76  -12.212 51.05   1   81.23  ? 226 LYS D CG  1 
ATOM   7352 C  CD  . LYS D 2 56  ? -49.61  -11.526 52.119  1   92.25  ? 226 LYS D CD  1 
ATOM   7353 C  CE  . LYS D 2 56  ? -50.141 -12.402 53.203  1   101.41 ? 226 LYS D CE  1 
ATOM   7354 N  NZ  . LYS D 2 56  ? -50.887 -11.514 54.096  1   102.13 ? 226 LYS D NZ  1 
ATOM   7355 N  N   . LEU D 2 57  ? -46.325 -11.54  46.69   1   57.52  ? 227 LEU D N   1 
ATOM   7356 C  CA  . LEU D 2 57  ? -46.013 -10.835 45.456  1   57.67  ? 227 LEU D CA  1 
ATOM   7357 C  C   . LEU D 2 57  ? -47.137 -11.054 44.454  1   59.22  ? 227 LEU D C   1 
ATOM   7358 O  O   . LEU D 2 57  ? -47.868 -12.035 44.581  1   66.37  ? 227 LEU D O   1 
ATOM   7359 C  CB  . LEU D 2 57  ? -44.7   -11.363 44.881  1   52.07  ? 227 LEU D CB  1 
ATOM   7360 C  CG  . LEU D 2 57  ? -43.511 -11.367 45.845  1   53.79  ? 227 LEU D CG  1 
ATOM   7361 C  CD1 . LEU D 2 57  ? -42.287 -11.953 45.15   1   42.61  ? 227 LEU D CD1 1 
ATOM   7362 C  CD2 . LEU D 2 57  ? -43.225 -9.972  46.412  1   49.95  ? 227 LEU D CD2 1 
ATOM   7363 N  N   . GLN D 2 58  ? -47.242 -10.155 43.455  1   61.26  ? 228 GLN D N   1 
ATOM   7364 C  CA  . GLN D 2 58  ? -48.195 -10.302 42.357  1   61.74  ? 228 GLN D CA  1 
ATOM   7365 C  C   . GLN D 2 58  ? -47.849 -11.555 41.556  1   65.28  ? 228 GLN D C   1 
ATOM   7366 O  O   . GLN D 2 58  ? -46.676 -11.923 41.469  1   59.24  ? 228 GLN D O   1 
ATOM   7367 C  CB  . GLN D 2 58  ? -48.107 -9.123  41.393  1   56.44  ? 228 GLN D CB  1 
ATOM   7368 C  CG  . GLN D 2 58  ? -48.463 -7.79   42.033  1   57.19  ? 228 GLN D CG  1 
ATOM   7369 C  CD  . GLN D 2 58  ? -49.912 -7.758  42.446  1   58.42  ? 228 GLN D CD  1 
ATOM   7370 O  OE1 . GLN D 2 58  ? -50.823 -7.616  41.624  1   64.61  ? 228 GLN D OE1 1 
ATOM   7371 N  NE2 . GLN D 2 58  ? -50.13  -7.917  43.737  1   54.33  ? 228 GLN D NE2 1 
ATOM   7372 N  N   . ASN D 2 59  ? -48.872 -12.19  40.967  1   66.71  ? 229 ASN D N   1 
ATOM   7373 C  CA  . ASN D 2 59  ? -48.648 -13.284 40.038  1   64.57  ? 229 ASN D CA  1 
ATOM   7374 C  C   . ASN D 2 59  ? -47.856 -12.811 38.822  1   60.11  ? 229 ASN D C   1 
ATOM   7375 O  O   . ASN D 2 59  ? -46.993 -13.549 38.343  1   58.32  ? 229 ASN D O   1 
ATOM   7376 C  CB  . ASN D 2 59  ? -49.942 -13.997 39.677  1   66.98  ? 229 ASN D CB  1 
ATOM   7377 C  CG  . ASN D 2 59  ? -50.483 -14.773 40.852  1   67.98  ? 229 ASN D CG  1 
ATOM   7378 O  OD1 . ASN D 2 59  ? -49.729 -15.212 41.727  1   64.67  ? 229 ASN D OD1 1 
ATOM   7379 N  ND2 . ASN D 2 59  ? -51.794 -14.909 40.915  1   66.95  ? 229 ASN D ND2 1 
ATOM   7380 N  N   . GLU D 2 60  ? -48.151 -11.584 38.352  1   58.15  ? 230 GLU D N   1 
ATOM   7381 C  CA  . GLU D 2 60  ? -47.437 -10.95  37.249  1   57.41  ? 230 GLU D CA  1 
ATOM   7382 C  C   . GLU D 2 60  ? -45.919 -10.949 37.473  1   57.63  ? 230 GLU D C   1 
ATOM   7383 O  O   . GLU D 2 60  ? -45.15  -11.126 36.529  1   59.88  ? 230 GLU D O   1 
ATOM   7384 C  CB  . GLU D 2 60  ? -47.955 -9.537  36.992  1   53.82  ? 230 GLU D CB  1 
ATOM   7385 C  CG  . GLU D 2 60  ? -47.131 -8.798  35.94   1   53.43  ? 230 GLU D CG  1 
ATOM   7386 C  CD  . GLU D 2 60  ? -47.287 -9.302  34.517  1   51.37  ? 230 GLU D CD  1 
ATOM   7387 O  OE1 . GLU D 2 60  ? -48.049 -10.263 34.311  1   53.88  ? 230 GLU D OE1 1 
ATOM   7388 O  OE2 . GLU D 2 60  ? -46.694 -8.699  33.607  1   47.95  ? 230 GLU D OE2 1 
ATOM   7389 N  N   . THR D 2 61  ? -45.495 -10.776 38.734  1   57.38  ? 231 THR D N   1 
ATOM   7390 C  CA  . THR D 2 61  ? -44.086 -10.711 39.108  1   56.02  ? 231 THR D CA  1 
ATOM   7391 C  C   . THR D 2 61  ? -43.428 -12.065 38.848  1   54.36  ? 231 THR D C   1 
ATOM   7392 O  O   . THR D 2 61  ? -42.354 -12.107 38.258  1   57.65  ? 231 THR D O   1 
ATOM   7393 C  CB  . THR D 2 61  ? -43.904 -10.253 40.56   1   52.4   ? 231 THR D CB  1 
ATOM   7394 O  OG1 . THR D 2 61  ? -44.433 -8.934  40.648  1   55.17  ? 231 THR D OG1 1 
ATOM   7395 C  CG2 . THR D 2 61  ? -42.449 -10.193 40.985  1   48.26  ? 231 THR D CG2 1 
ATOM   7396 N  N   . LEU D 2 62  ? -44.083 -13.143 39.301  1   51.47  ? 232 LEU D N   1 
ATOM   7397 C  CA  . LEU D 2 62  ? -43.67  -14.514 39.047  1   49.88  ? 232 LEU D CA  1 
ATOM   7398 C  C   . LEU D 2 62  ? -43.518 -14.78  37.547  1   47.52  ? 232 LEU D C   1 
ATOM   7399 O  O   . LEU D 2 62  ? -42.506 -15.33  37.117  1   51.46  ? 232 LEU D O   1 
ATOM   7400 C  CB  . LEU D 2 62  ? -44.662 -15.472 39.704  1   49.97  ? 232 LEU D CB  1 
ATOM   7401 C  CG  . LEU D 2 62  ? -44.503 -16.948 39.323  1   52.32  ? 232 LEU D CG  1 
ATOM   7402 C  CD1 . LEU D 2 62  ? -43.2   -17.578 39.805  1   52.63  ? 232 LEU D CD1 1 
ATOM   7403 C  CD2 . LEU D 2 62  ? -45.688 -17.74  39.835  1   54.39  ? 232 LEU D CD2 1 
ATOM   7404 N  N   . HIS D 2 63  ? -44.522 -14.398 36.748  1   50.8   ? 233 HIS D N   1 
ATOM   7405 C  CA  . HIS D 2 63  ? -44.463 -14.595 35.298  1   56.35  ? 233 HIS D CA  1 
ATOM   7406 C  C   . HIS D 2 63  ? -43.246 -13.891 34.696  1   55.51  ? 233 HIS D C   1 
ATOM   7407 O  O   . HIS D 2 63  ? -42.501 -14.5   33.928  1   59.76  ? 233 HIS D O   1 
ATOM   7408 C  CB  . HIS D 2 63  ? -45.767 -14.205 34.58   1   52.94  ? 233 HIS D CB  1 
ATOM   7409 C  CG  . HIS D 2 63  ? -46.851 -15.229 34.639  1   56.95  ? 233 HIS D CG  1 
ATOM   7410 N  ND1 . HIS D 2 63  ? -47.577 -15.46  35.793  1   57.76  ? 233 HIS D ND1 1 
ATOM   7411 C  CD2 . HIS D 2 63  ? -47.317 -16.086 33.724  1   54.66  ? 233 HIS D CD2 1 
ATOM   7412 C  CE1 . HIS D 2 63  ? -48.469 -16.411 35.567  1   62.2   ? 233 HIS D CE1 1 
ATOM   7413 N  NE2 . HIS D 2 63  ? -48.329 -16.809 34.321  1   62.48  ? 233 HIS D NE2 1 
ATOM   7414 N  N   . LEU D 2 64  ? -43.046 -12.618 35.075  1   51.88  ? 234 LEU D N   1 
ATOM   7415 C  CA  . LEU D 2 64  ? -41.936 -11.825 34.567  1   49.72  ? 234 LEU D CA  1 
ATOM   7416 C  C   . LEU D 2 64  ? -40.594 -12.484 34.883  1   48.95  ? 234 LEU D C   1 
ATOM   7417 O  O   . LEU D 2 64  ? -39.715 -12.536 34.015  1   52.24  ? 234 LEU D O   1 
ATOM   7418 C  CB  . LEU D 2 64  ? -41.98  -10.43  35.176  1   45.12  ? 234 LEU D CB  1 
ATOM   7419 C  CG  . LEU D 2 64  ? -43.049 -9.496  34.624  1   47     ? 234 LEU D CG  1 
ATOM   7420 C  CD1 . LEU D 2 64  ? -43.084 -8.241  35.511  1   49.95  ? 234 LEU D CD1 1 
ATOM   7421 C  CD2 . LEU D 2 64  ? -42.716 -9.15   33.178  1   42.07  ? 234 LEU D CD2 1 
ATOM   7422 N  N   . ALA D 2 65  ? -40.416 -12.912 36.144  1   41.82  ? 235 ALA D N   1 
ATOM   7423 C  CA  . ALA D 2 65  ? -39.149 -13.491 36.565  1   44.48  ? 235 ALA D CA  1 
ATOM   7424 C  C   . ALA D 2 65  ? -38.79  -14.706 35.699  1   47.04  ? 235 ALA D C   1 
ATOM   7425 O  O   . ALA D 2 65  ? -37.625 -14.884 35.329  1   48.5   ? 235 ALA D O   1 
ATOM   7426 C  CB  . ALA D 2 65  ? -39.203 -13.844 38.037  1   46.39  ? 235 ALA D CB  1 
ATOM   7427 N  N   . VAL D 2 66  ? -39.802 -15.526 35.367  1   44.02  ? 236 VAL D N   1 
ATOM   7428 C  CA  . VAL D 2 66  ? -39.558 -16.736 34.609  1   43.12  ? 236 VAL D CA  1 
ATOM   7429 C  C   . VAL D 2 66  ? -39.147 -16.355 33.185  1   45.44  ? 236 VAL D C   1 
ATOM   7430 O  O   . VAL D 2 66  ? -38.213 -16.945 32.625  1   50.84  ? 236 VAL D O   1 
ATOM   7431 C  CB  . VAL D 2 66  ? -40.767 -17.682 34.696  1   48.26  ? 236 VAL D CB  1 
ATOM   7432 C  CG1 . VAL D 2 66  ? -40.624 -18.842 33.737  1   45.11  ? 236 VAL D CG1 1 
ATOM   7433 C  CG2 . VAL D 2 66  ? -41.012 -18.199 36.124  1   47.9   ? 236 VAL D CG2 1 
ATOM   7434 N  N   . ASN D 2 67  ? -39.785 -15.316 32.624  1   43.37  ? 237 ASN D N   1 
ATOM   7435 C  CA  . ASN D 2 67  ? -39.376 -14.787 31.334  1   44.11  ? 237 ASN D CA  1 
ATOM   7436 C  C   . ASN D 2 67  ? -37.879 -14.429 31.357  1   51.21  ? 237 ASN D C   1 
ATOM   7437 O  O   . ASN D 2 67  ? -37.137 -14.763 30.408  1   49.37  ? 237 ASN D O   1 
ATOM   7438 C  CB  . ASN D 2 67  ? -40.251 -13.616 30.9    1   43.33  ? 237 ASN D CB  1 
ATOM   7439 C  CG  . ASN D 2 67  ? -39.788 -13.017 29.586  1   46.05  ? 237 ASN D CG  1 
ATOM   7440 O  OD1 . ASN D 2 67  ? -38.981 -12.08  29.568  1   49.04  ? 237 ASN D OD1 1 
ATOM   7441 N  ND2 . ASN D 2 67  ? -40.206 -13.593 28.47   1   45.3   ? 237 ASN D ND2 1 
ATOM   7442 N  N   . TYR D 2 68  ? -37.442 -13.762 32.45   1   48.52  ? 238 TYR D N   1 
ATOM   7443 C  CA  . TYR D 2 68  ? -36.086 -13.221 32.55   1   48.38  ? 238 TYR D CA  1 
ATOM   7444 C  C   . TYR D 2 68  ? -35.044 -14.336 32.617  1   49.23  ? 238 TYR D C   1 
ATOM   7445 O  O   . TYR D 2 68  ? -33.958 -14.216 32.041  1   50.86  ? 238 TYR D O   1 
ATOM   7446 C  CB  . TYR D 2 68  ? -35.896 -12.288 33.743  1   44.04  ? 238 TYR D CB  1 
ATOM   7447 C  CG  . TYR D 2 68  ? -36.802 -11.069 33.777  1   43.52  ? 238 TYR D CG  1 
ATOM   7448 C  CD1 . TYR D 2 68  ? -37.531 -10.674 32.658  1   44.84  ? 238 TYR D CD1 1 
ATOM   7449 C  CD2 . TYR D 2 68  ? -36.929 -10.325 34.942  1   45.08  ? 238 TYR D CD2 1 
ATOM   7450 C  CE1 . TYR D 2 68  ? -38.361 -9.565  32.69   1   45.26  ? 238 TYR D CE1 1 
ATOM   7451 C  CE2 . TYR D 2 68  ? -37.762 -9.222  34.99   1   45.3   ? 238 TYR D CE2 1 
ATOM   7452 C  CZ  . TYR D 2 68  ? -38.478 -8.852  33.867  1   45     ? 238 TYR D CZ  1 
ATOM   7453 O  OH  . TYR D 2 68  ? -39.277 -7.765  33.903  1   46.46  ? 238 TYR D OH  1 
ATOM   7454 N  N   . ILE D 2 69  ? -35.402 -15.422 33.309  1   52.13  ? 239 ILE D N   1 
ATOM   7455 C  CA  . ILE D 2 69  ? -34.549 -16.594 33.491  1   51.95  ? 239 ILE D CA  1 
ATOM   7456 C  C   . ILE D 2 69  ? -34.352 -17.322 32.16   1   51.71  ? 239 ILE D C   1 
ATOM   7457 O  O   . ILE D 2 69  ? -33.233 -17.691 31.798  1   48.44  ? 239 ILE D O   1 
ATOM   7458 C  CB  . ILE D 2 69  ? -35.144 -17.521 34.562  1   47.7   ? 239 ILE D CB  1 
ATOM   7459 C  CG1 . ILE D 2 69  ? -35.115 -16.835 35.941  1   43.31  ? 239 ILE D CG1 1 
ATOM   7460 C  CG2 . ILE D 2 69  ? -34.429 -18.87  34.547  1   44.32  ? 239 ILE D CG2 1 
ATOM   7461 C  CD1 . ILE D 2 69  ? -36.104 -17.411 36.935  1   41.83  ? 239 ILE D CD1 1 
ATOM   7462 N  N   . ASP D 2 70  ? -35.455 -17.521 31.441  1   51.64  ? 240 ASP D N   1 
ATOM   7463 C  CA  . ASP D 2 70  ? -35.411 -18.26  30.195  1   52.83  ? 240 ASP D CA  1 
ATOM   7464 C  C   . ASP D 2 70  ? -34.553 -17.496 29.201  1   50.23  ? 240 ASP D C   1 
ATOM   7465 O  O   . ASP D 2 70  ? -33.712 -18.109 28.547  1   49.5   ? 240 ASP D O   1 
ATOM   7466 C  CB  . ASP D 2 70  ? -36.802 -18.657 29.722  1   54.34  ? 240 ASP D CB  1 
ATOM   7467 C  CG  . ASP D 2 70  ? -37.469 -19.699 30.605  1   58.19  ? 240 ASP D CG  1 
ATOM   7468 O  OD1 . ASP D 2 70  ? -36.724 -20.566 31.125  1   55.63  ? 240 ASP D OD1 1 
ATOM   7469 O  OD2 . ASP D 2 70  ? -38.716 -19.644 30.761  1   58.5   ? 240 ASP D OD2 1 
ATOM   7470 N  N   . ARG D 2 71  ? -34.738 -16.167 29.123  1   49.45  ? 241 ARG D N   1 
ATOM   7471 C  CA  . ARG D 2 71  ? -33.981 -15.373 28.158  1   49.65  ? 241 ARG D CA  1 
ATOM   7472 C  C   . ARG D 2 71  ? -32.495 -15.387 28.531  1   52     ? 241 ARG D C   1 
ATOM   7473 O  O   . ARG D 2 71  ? -31.629 -15.421 27.655  1   55.48  ? 241 ARG D O   1 
ATOM   7474 C  CB  . ARG D 2 71  ? -34.51  -13.943 28.026  1   48.2   ? 241 ARG D CB  1 
ATOM   7475 C  CG  . ARG D 2 71  ? -35.756 -13.833 27.163  1   53.4   ? 241 ARG D CG  1 
ATOM   7476 C  CD  . ARG D 2 71  ? -36.667 -12.688 27.566  1   52.19  ? 241 ARG D CD  1 
ATOM   7477 N  NE  . ARG D 2 71  ? -36.052 -11.448 27.102  1   57.29  ? 241 ARG D NE  1 
ATOM   7478 C  CZ  . ARG D 2 71  ? -36.282 -10.267 27.657  1   56.03  ? 241 ARG D CZ  1 
ATOM   7479 N  NH1 . ARG D 2 71  ? -37.183 -10.134 28.622  1   54.05  ? 241 ARG D NH1 1 
ATOM   7480 N  NH2 . ARG D 2 71  ? -35.569 -9.235  27.252  1   48.2   ? 241 ARG D NH2 1 
ATOM   7481 N  N   . PHE D 2 72  ? -32.211 -15.381 29.842  1   46.5   ? 242 PHE D N   1 
ATOM   7482 C  CA  . PHE D 2 72  ? -30.838 -15.363 30.316  1   46.71  ? 242 PHE D CA  1 
ATOM   7483 C  C   . PHE D 2 72  ? -30.167 -16.701 29.996  1   53.1   ? 242 PHE D C   1 
ATOM   7484 O  O   . PHE D 2 72  ? -29.045 -16.729 29.491  1   57.72  ? 242 PHE D O   1 
ATOM   7485 C  CB  . PHE D 2 72  ? -30.808 -15.057 31.819  1   44.69  ? 242 PHE D CB  1 
ATOM   7486 C  CG  . PHE D 2 72  ? -29.407 -14.914 32.388  1   43.44  ? 242 PHE D CG  1 
ATOM   7487 C  CD1 . PHE D 2 72  ? -28.729 -16.025 32.89   1   46.88  ? 242 PHE D CD1 1 
ATOM   7488 C  CD2 . PHE D 2 72  ? -28.775 -13.678 32.409  1   42.57  ? 242 PHE D CD2 1 
ATOM   7489 C  CE1 . PHE D 2 72  ? -27.458 -15.9   33.419  1   43.05  ? 242 PHE D CE1 1 
ATOM   7490 C  CE2 . PHE D 2 72  ? -27.504 -13.561 32.945  1   46.1   ? 242 PHE D CE2 1 
ATOM   7491 C  CZ  . PHE D 2 72  ? -26.853 -14.668 33.445  1   44.21  ? 242 PHE D CZ  1 
ATOM   7492 N  N   . LEU D 2 73  ? -30.849 -17.811 30.31   1   51.18  ? 243 LEU D N   1 
ATOM   7493 C  CA  . LEU D 2 73  ? -30.351 -19.141 29.991  1   51.33  ? 243 LEU D CA  1 
ATOM   7494 C  C   . LEU D 2 73  ? -30.358 -19.413 28.478  1   48.21  ? 243 LEU D C   1 
ATOM   7495 O  O   . LEU D 2 73  ? -29.675 -20.322 28.015  1   53.06  ? 243 LEU D O   1 
ATOM   7496 C  CB  . LEU D 2 73  ? -31.17  -20.162 30.781  1   48.09  ? 243 LEU D CB  1 
ATOM   7497 C  CG  . LEU D 2 73  ? -31.063 -20.077 32.309  1   47.54  ? 243 LEU D CG  1 
ATOM   7498 C  CD1 . LEU D 2 73  ? -31.939 -21.12  32.953  1   47.19  ? 243 LEU D CD1 1 
ATOM   7499 C  CD2 . LEU D 2 73  ? -29.647 -20.26  32.81   1   48.24  ? 243 LEU D CD2 1 
ATOM   7500 N  N   . SER D 2 74  ? -31.113 -18.629 27.702  1   47.3   ? 244 SER D N   1 
ATOM   7501 C  CA  . SER D 2 74  ? -31.049 -18.666 26.241  1   52.29  ? 244 SER D CA  1 
ATOM   7502 C  C   . SER D 2 74  ? -29.729 -18.109 25.696  1   50.75  ? 244 SER D C   1 
ATOM   7503 O  O   . SER D 2 74  ? -29.383 -18.335 24.54   1   50.01  ? 244 SER D O   1 
ATOM   7504 C  CB  . SER D 2 74  ? -32.211 -17.926 25.618  1   50.04  ? 244 SER D CB  1 
ATOM   7505 O  OG  . SER D 2 74  ? -33.449 -18.56  25.929  1   58.95  ? 244 SER D OG  1 
ATOM   7506 N  N   . SER D 2 75  ? -28.98  -17.376 26.531  1   50.92  ? 245 SER D N   1 
ATOM   7507 C  CA  . SER D 2 75  ? -27.748 -16.753 26.066  1   53.62  ? 245 SER D CA  1 
ATOM   7508 C  C   . SER D 2 75  ? -26.546 -16.989 26.985  1   52.17  ? 245 SER D C   1 
ATOM   7509 O  O   . SER D 2 75  ? -25.433 -16.634 26.622  1   57.61  ? 245 SER D O   1 
ATOM   7510 C  CB  . SER D 2 75  ? -27.948 -15.278 25.748  1   62.34  ? 245 SER D CB  1 
ATOM   7511 O  OG  . SER D 2 75  ? -28.294 -14.531 26.912  1   65.95  ? 245 SER D OG  1 
ATOM   7512 N  N   . MET D 2 76  ? -26.743 -17.576 28.173  1   52.13  ? 246 MET D N   1 
ATOM   7513 C  CA  . MET D 2 76  ? -25.635 -17.737 29.11   1   51.51  ? 246 MET D CA  1 
ATOM   7514 C  C   . MET D 2 76  ? -25.62  -19.162 29.652  1   53.91  ? 246 MET D C   1 
ATOM   7515 O  O   . MET D 2 76  ? -26.585 -19.691 30.201  1   56.2   ? 246 MET D O   1 
ATOM   7516 C  CB  . MET D 2 76  ? -25.697 -16.775 30.303  1   49.51  ? 246 MET D CB  1 
ATOM   7517 C  CG  . MET D 2 76  ? -25.798 -15.301 29.936  1   49.37  ? 246 MET D CG  1 
ATOM   7518 S  SD  . MET D 2 76  ? -24.259 -14.589 29.331  1   54.05  ? 246 MET D SD  1 
ATOM   7519 C  CE  . MET D 2 76  ? -23.345 -14.457 30.875  1   43.5   ? 246 MET D CE  1 
ATOM   7520 N  N   . SER D 2 77  ? -24.481 -19.79  29.459  1   51.79  ? 247 SER D N   1 
ATOM   7521 C  CA  . SER D 2 77  ? -24.244 -21.093 30.02   1   50.68  ? 247 SER D CA  1 
ATOM   7522 C  C   . SER D 2 77  ? -24.061 -20.878 31.529  1   50.7   ? 247 SER D C   1 
ATOM   7523 O  O   . SER D 2 77  ? -23.359 -19.956 31.927  1   53.21  ? 247 SER D O   1 
ATOM   7524 C  CB  . SER D 2 77  ? -23.027 -21.587 29.269  1   52.61  ? 247 SER D CB  1 
ATOM   7525 O  OG  . SER D 2 77  ? -22.65  -22.87  29.69   1   73.29  ? 247 SER D OG  1 
ATOM   7526 N  N   . VAL D 2 78  ? -24.768 -21.644 32.376  1   51.74  ? 248 VAL D N   1 
ATOM   7527 C  CA  . VAL D 2 78  ? -24.748 -21.491 33.831  1   48.74  ? 248 VAL D CA  1 
ATOM   7528 C  C   . VAL D 2 78  ? -24.582 -22.861 34.495  1   53.17  ? 248 VAL D C   1 
ATOM   7529 O  O   . VAL D 2 78  ? -25.287 -23.803 34.128  1   56.96  ? 248 VAL D O   1 
ATOM   7530 C  CB  . VAL D 2 78  ? -26.055 -20.84  34.324  1   46.73  ? 248 VAL D CB  1 
ATOM   7531 C  CG1 . VAL D 2 78  ? -26.198 -20.912 35.84   1   44.95  ? 248 VAL D CG1 1 
ATOM   7532 C  CG2 . VAL D 2 78  ? -26.209 -19.408 33.84   1   42.27  ? 248 VAL D CG2 1 
ATOM   7533 N  N   . LEU D 2 79  ? -23.682 -22.961 35.491  1   50.84  ? 249 LEU D N   1 
ATOM   7534 C  CA  . LEU D 2 79  ? -23.526 -24.187 36.265  1   54.25  ? 249 LEU D CA  1 
ATOM   7535 C  C   . LEU D 2 79  ? -24.683 -24.34  37.252  1   59.92  ? 249 LEU D C   1 
ATOM   7536 O  O   . LEU D 2 79  ? -25.274 -23.353 37.696  1   62.52  ? 249 LEU D O   1 
ATOM   7537 C  CB  . LEU D 2 79  ? -22.182 -24.276 36.989  1   52.17  ? 249 LEU D CB  1 
ATOM   7538 C  CG  . LEU D 2 79  ? -20.942 -24.234 36.094  1   57.02  ? 249 LEU D CG  1 
ATOM   7539 C  CD1 . LEU D 2 79  ? -19.728 -24.678 36.87   1   57.49  ? 249 LEU D CD1 1 
ATOM   7540 C  CD2 . LEU D 2 79  ? -21.126 -25.045 34.808  1   56.37  ? 249 LEU D CD2 1 
ATOM   7541 N  N   . ARG D 2 80  ? -24.946 -25.592 37.643  1   64.56  ? 250 ARG D N   1 
ATOM   7542 C  CA  . ARG D 2 80  ? -26.073 -25.955 38.492  1   63.46  ? 250 ARG D CA  1 
ATOM   7543 C  C   . ARG D 2 80  ? -26.065 -25.186 39.813  1   62.02  ? 250 ARG D C   1 
ATOM   7544 O  O   . ARG D 2 80  ? -27.112 -24.73  40.265  1   61.49  ? 250 ARG D O   1 
ATOM   7545 C  CB  . ARG D 2 80  ? -25.963 -27.45  38.781  1   63.55  ? 250 ARG D CB  1 
ATOM   7546 C  CG  . ARG D 2 80  ? -27.184 -27.997 39.497  1   71.12  ? 250 ARG D CG  1 
ATOM   7547 C  CD  . ARG D 2 80  ? -26.947 -29.476 39.688  1   82.67  ? 250 ARG D CD  1 
ATOM   7548 N  NE  . ARG D 2 80  ? -25.672 -29.819 40.332  1   76.19  ? 250 ARG D NE  1 
ATOM   7549 C  CZ  . ARG D 2 80  ? -25.217 -31.066 40.386  1   83.39  ? 250 ARG D CZ  1 
ATOM   7550 N  NH1 . ARG D 2 80  ? -25.894 -32.064 39.813  1   79.68  ? 250 ARG D NH1 1 
ATOM   7551 N  NH2 . ARG D 2 80  ? -24.066 -31.298 40.995  1   84.28  ? 250 ARG D NH2 1 
ATOM   7552 N  N   . GLY D 2 81  ? -24.883 -25.057 40.431  1   59.03  ? 251 GLY D N   1 
ATOM   7553 C  CA  . GLY D 2 81  ? -24.75  -24.404 41.721  1   56.41  ? 251 GLY D CA  1 
ATOM   7554 C  C   . GLY D 2 81  ? -25.02  -22.901 41.667  1   58.68  ? 251 GLY D C   1 
ATOM   7555 O  O   . GLY D 2 81  ? -24.989 -22.242 42.705  1   64.32  ? 251 GLY D O   1 
ATOM   7556 N  N   . LYS D 2 82  ? -25.294 -22.37  40.467  1   55.87  ? 252 LYS D N   1 
ATOM   7557 C  CA  . LYS D 2 82  ? -25.513 -20.943 40.286  1   53.48  ? 252 LYS D CA  1 
ATOM   7558 C  C   . LYS D 2 82  ? -26.893 -20.678 39.702  1   51.4   ? 252 LYS D C   1 
ATOM   7559 O  O   . LYS D 2 82  ? -27.271 -19.521 39.547  1   51.54  ? 252 LYS D O   1 
ATOM   7560 C  CB  . LYS D 2 82  ? -24.504 -20.306 39.322  1   50.41  ? 252 LYS D CB  1 
ATOM   7561 C  CG  . LYS D 2 82  ? -23.094 -20.177 39.869  1   46.72  ? 252 LYS D CG  1 
ATOM   7562 C  CD  . LYS D 2 82  ? -23.163 -19.399 41.168  1   45.8   ? 252 LYS D CD  1 
ATOM   7563 C  CE  . LYS D 2 82  ? -21.827 -18.89  41.583  1   46.48  ? 252 LYS D CE  1 
ATOM   7564 N  NZ  . LYS D 2 82  ? -21.071 -20.088 41.946  1   52.69  ? 252 LYS D NZ  1 
ATOM   7565 N  N   . LEU D 2 83  ? -27.635 -21.743 39.377  1   52.02  ? 253 LEU D N   1 
ATOM   7566 C  CA  . LEU D 2 83  ? -28.97  -21.586 38.809  1   49.59  ? 253 LEU D CA  1 
ATOM   7567 C  C   . LEU D 2 83  ? -29.859 -20.791 39.769  1   50.32  ? 253 LEU D C   1 
ATOM   7568 O  O   . LEU D 2 83  ? -30.589 -19.924 39.323  1   49.45  ? 253 LEU D O   1 
ATOM   7569 C  CB  . LEU D 2 83  ? -29.541 -22.966 38.504  1   48.23  ? 253 LEU D CB  1 
ATOM   7570 C  CG  . LEU D 2 83  ? -30.975 -23.021 37.981  1   49.9   ? 253 LEU D CG  1 
ATOM   7571 C  CD1 . LEU D 2 83  ? -31.073 -22.243 36.671  1   49.34  ? 253 LEU D CD1 1 
ATOM   7572 C  CD2 . LEU D 2 83  ? -31.373 -24.496 37.786  1   52.57  ? 253 LEU D CD2 1 
ATOM   7573 N  N   . GLN D 2 84  ? -29.78  -21.056 41.08   1   47.96  ? 254 GLN D N   1 
ATOM   7574 C  CA  . GLN D 2 84  ? -30.587 -20.306 42.032  1   48.79  ? 254 GLN D CA  1 
ATOM   7575 C  C   . GLN D 2 84  ? -30.183 -18.833 42.047  1   48.31  ? 254 GLN D C   1 
ATOM   7576 O  O   . GLN D 2 84  ? -31.04  -17.958 42.197  1   46.69  ? 254 GLN D O   1 
ATOM   7577 C  CB  . GLN D 2 84  ? -30.479 -20.862 43.45   1   46.31  ? 254 GLN D CB  1 
ATOM   7578 C  CG  . GLN D 2 84  ? -31.53  -20.297 44.392  1   46.08  ? 254 GLN D CG  1 
ATOM   7579 C  CD  . GLN D 2 84  ? -31.516 -20.941 45.763  1   54.51  ? 254 GLN D CD  1 
ATOM   7580 O  OE1 . GLN D 2 84  ? -32.515 -20.879 46.492  1   57.45  ? 254 GLN D OE1 1 
ATOM   7581 N  NE2 . GLN D 2 84  ? -30.405 -21.575 46.123  1   51.11  ? 254 GLN D NE2 1 
ATOM   7582 N  N   . LEU D 2 85  ? -28.877 -18.579 41.888  1   45.07  ? 255 LEU D N   1 
ATOM   7583 C  CA  . LEU D 2 85  ? -28.399 -17.217 41.91   1   44.83  ? 255 LEU D CA  1 
ATOM   7584 C  C   . LEU D 2 85  ? -29.082 -16.438 40.793  1   44.65  ? 255 LEU D C   1 
ATOM   7585 O  O   . LEU D 2 85  ? -29.531 -15.327 41.021  1   43.94  ? 255 LEU D O   1 
ATOM   7586 C  CB  . LEU D 2 85  ? -26.88  -17.134 41.843  1   47.98  ? 255 LEU D CB  1 
ATOM   7587 C  CG  . LEU D 2 85  ? -26.325 -15.709 41.926  1   47.89  ? 255 LEU D CG  1 
ATOM   7588 C  CD1 . LEU D 2 85  ? -26.866 -14.971 43.141  1   46.38  ? 255 LEU D CD1 1 
ATOM   7589 C  CD2 . LEU D 2 85  ? -24.826 -15.719 41.969  1   47.45  ? 255 LEU D CD2 1 
ATOM   7590 N  N   . VAL D 2 86  ? -29.217 -17.056 39.612  1   46.6   ? 256 VAL D N   1 
ATOM   7591 C  CA  . VAL D 2 86  ? -29.901 -16.429 38.488  1   44.06  ? 256 VAL D CA  1 
ATOM   7592 C  C   . VAL D 2 86  ? -31.368 -16.138 38.836  1   46.37  ? 256 VAL D C   1 
ATOM   7593 O  O   . VAL D 2 86  ? -31.863 -15.028 38.624  1   43.25  ? 256 VAL D O   1 
ATOM   7594 C  CB  . VAL D 2 86  ? -29.761 -17.285 37.215  1   40.81  ? 256 VAL D CB  1 
ATOM   7595 C  CG1 . VAL D 2 86  ? -30.601 -16.722 36.074  1   37.33  ? 256 VAL D CG1 1 
ATOM   7596 C  CG2 . VAL D 2 86  ? -28.298 -17.442 36.799  1   41     ? 256 VAL D CG2 1 
ATOM   7597 N  N   . GLY D 2 87  ? -32.063 -17.144 39.382  1   44.96  ? 257 GLY D N   1 
ATOM   7598 C  CA  . GLY D 2 87  ? -33.472 -17.033 39.718  1   44.19  ? 257 GLY D CA  1 
ATOM   7599 C  C   . GLY D 2 87  ? -33.729 -15.946 40.767  1   46.96  ? 257 GLY D C   1 
ATOM   7600 O  O   . GLY D 2 87  ? -34.693 -15.203 40.626  1   46.56  ? 257 GLY D O   1 
ATOM   7601 N  N   . THR D 2 88  ? -32.895 -15.877 41.82   1   43.06  ? 258 THR D N   1 
ATOM   7602 C  CA  . THR D 2 88  ? -33.039 -14.894 42.891  1   45.51  ? 258 THR D CA  1 
ATOM   7603 C  C   . THR D 2 88  ? -32.88  -13.486 42.304  1   45.15  ? 258 THR D C   1 
ATOM   7604 O  O   . THR D 2 88  ? -33.656 -12.59  42.603  1   43.28  ? 258 THR D O   1 
ATOM   7605 C  CB  . THR D 2 88  ? -32.005 -15.148 43.989  1   46.36  ? 258 THR D CB  1 
ATOM   7606 O  OG1 . THR D 2 88  ? -32.205 -16.487 44.426  1   59.94  ? 258 THR D OG1 1 
ATOM   7607 C  CG2 . THR D 2 88  ? -32.182 -14.254 45.195  1   47.75  ? 258 THR D CG2 1 
ATOM   7608 N  N   . ALA D 2 89  ? -31.887 -13.308 41.431  1   45.07  ? 259 ALA D N   1 
ATOM   7609 C  CA  . ALA D 2 89  ? -31.658 -12.033 40.78   1   45.92  ? 259 ALA D CA  1 
ATOM   7610 C  C   . ALA D 2 89  ? -32.875 -11.69  39.933  1   49.58  ? 259 ALA D C   1 
ATOM   7611 O  O   . ALA D 2 89  ? -33.381 -10.573 40.015  1   57.2   ? 259 ALA D O   1 
ATOM   7612 C  CB  . ALA D 2 89  ? -30.403 -12.096 39.959  1   44.06  ? 259 ALA D CB  1 
ATOM   7613 N  N   . ALA D 2 90  ? -33.382 -12.672 39.179  1   48.71  ? 260 ALA D N   1 
ATOM   7614 C  CA  . ALA D 2 90  ? -34.487 -12.427 38.261  1   44.81  ? 260 ALA D CA  1 
ATOM   7615 C  C   . ALA D 2 90  ? -35.728 -11.975 39.032  1   46.39  ? 260 ALA D C   1 
ATOM   7616 O  O   . ALA D 2 90  ? -36.408 -11.027 38.629  1   52.45  ? 260 ALA D O   1 
ATOM   7617 C  CB  . ALA D 2 90  ? -34.744 -13.661 37.446  1   44.85  ? 260 ALA D CB  1 
ATOM   7618 N  N   . MET D 2 91  ? -35.998 -12.643 40.159  1   42.33  ? 261 MET D N   1 
ATOM   7619 C  CA  . MET D 2 91  ? -37.151 -12.341 40.988  1   44.66  ? 261 MET D CA  1 
ATOM   7620 C  C   . MET D 2 91  ? -36.984 -10.931 41.554  1   47.98  ? 261 MET D C   1 
ATOM   7621 O  O   . MET D 2 91  ? -37.929 -10.146 41.529  1   50.29  ? 261 MET D O   1 
ATOM   7622 C  CB  . MET D 2 91  ? -37.285 -13.379 42.111  1   45.73  ? 261 MET D CB  1 
ATOM   7623 C  CG  . MET D 2 91  ? -38.637 -13.448 42.794  1   50.57  ? 261 MET D CG  1 
ATOM   7624 S  SD  . MET D 2 91  ? -39.935 -13.757 41.584  1   57.95  ? 261 MET D SD  1 
ATOM   7625 C  CE  . MET D 2 91  ? -41.129 -14.734 42.497  1   53.93  ? 261 MET D CE  1 
ATOM   7626 N  N   . LEU D 2 92  ? -35.77  -10.619 42.029  1   44.09  ? 262 LEU D N   1 
ATOM   7627 C  CA  . LEU D 2 92  ? -35.451 -9.292  42.516  1   45.17  ? 262 LEU D CA  1 
ATOM   7628 C  C   . LEU D 2 92  ? -35.817 -8.253  41.453  1   46.63  ? 262 LEU D C   1 
ATOM   7629 O  O   . LEU D 2 92  ? -36.489 -7.259  41.729  1   47.29  ? 262 LEU D O   1 
ATOM   7630 C  CB  . LEU D 2 92  ? -33.972 -9.217  42.891  1   41.47  ? 262 LEU D CB  1 
ATOM   7631 C  CG  . LEU D 2 92  ? -33.464 -7.808  43.236  1   42.17  ? 262 LEU D CG  1 
ATOM   7632 C  CD1 . LEU D 2 92  ? -34.267 -7.171  44.366  1   39.85  ? 262 LEU D CD1 1 
ATOM   7633 C  CD2 . LEU D 2 92  ? -31.998 -7.832  43.605  1   39.3   ? 262 LEU D CD2 1 
ATOM   7634 N  N   . LEU D 2 93  ? -35.363 -8.494  40.223  1   44.94  ? 263 LEU D N   1 
ATOM   7635 C  CA  . LEU D 2 93  ? -35.543 -7.541  39.15   1   42.2   ? 263 LEU D CA  1 
ATOM   7636 C  C   . LEU D 2 93  ? -37.019 -7.398  38.813  1   45.02  ? 263 LEU D C   1 
ATOM   7637 O  O   . LEU D 2 93  ? -37.454 -6.274  38.559  1   47.51  ? 263 LEU D O   1 
ATOM   7638 C  CB  . LEU D 2 93  ? -34.72  -8.013  37.959  1   43.2   ? 263 LEU D CB  1 
ATOM   7639 C  CG  . LEU D 2 93  ? -33.255 -7.574  37.932  1   45.42  ? 263 LEU D CG  1 
ATOM   7640 C  CD1 . LEU D 2 93  ? -32.577 -8.196  36.703  1   44.62  ? 263 LEU D CD1 1 
ATOM   7641 C  CD2 . LEU D 2 93  ? -33.157 -6.041  37.865  1   45.38  ? 263 LEU D CD2 1 
ATOM   7642 N  N   . ALA D 2 94  ? -37.763 -8.526  38.782  1   43.62  ? 264 ALA D N   1 
ATOM   7643 C  CA  . ALA D 2 94  ? -39.194 -8.497  38.477  1   42.53  ? 264 ALA D CA  1 
ATOM   7644 C  C   . ALA D 2 94  ? -39.968 -7.722  39.541  1   45.25  ? 264 ALA D C   1 
ATOM   7645 O  O   . ALA D 2 94  ? -40.817 -6.901  39.208  1   51.14  ? 264 ALA D O   1 
ATOM   7646 C  CB  . ALA D 2 94  ? -39.748 -9.876  38.351  1   42.01  ? 264 ALA D CB  1 
ATOM   7647 N  N   . SER D 2 95  ? -39.616 -7.945  40.814  1   44.21  ? 265 SER D N   1 
ATOM   7648 C  CA  . SER D 2 95  ? -40.175 -7.222  41.943  1   46.91  ? 265 SER D CA  1 
ATOM   7649 C  C   . SER D 2 95  ? -40.001 -5.713  41.786  1   47.92  ? 265 SER D C   1 
ATOM   7650 O  O   . SER D 2 95  ? -40.973 -4.965  41.892  1   48.47  ? 265 SER D O   1 
ATOM   7651 C  CB  . SER D 2 95  ? -39.57  -7.71   43.221  1   47.44  ? 265 SER D CB  1 
ATOM   7652 O  OG  . SER D 2 95  ? -39.962 -9.053  43.438  1   51.43  ? 265 SER D OG  1 
ATOM   7653 N  N   . LYS D 2 96  ? -38.763 -5.283  41.504  1   45.63  ? 266 LYS D N   1 
ATOM   7654 C  CA  . LYS D 2 96  ? -38.471 -3.879  41.286  1   44.2   ? 266 LYS D CA  1 
ATOM   7655 C  C   . LYS D 2 96  ? -39.276 -3.331  40.112  1   45.61  ? 266 LYS D C   1 
ATOM   7656 O  O   . LYS D 2 96  ? -39.653 -2.16   40.13   1   47.62  ? 266 LYS D O   1 
ATOM   7657 C  CB  . LYS D 2 96  ? -36.973 -3.688  41.049  1   45.1   ? 266 LYS D CB  1 
ATOM   7658 C  CG  . LYS D 2 96  ? -36.139 -3.764  42.316  1   41.62  ? 266 LYS D CG  1 
ATOM   7659 C  CD  . LYS D 2 96  ? -34.674 -3.535  41.987  1   40.08  ? 266 LYS D CD  1 
ATOM   7660 C  CE  . LYS D 2 96  ? -33.783 -3.489  43.19   1   40.77  ? 266 LYS D CE  1 
ATOM   7661 N  NZ  . LYS D 2 96  ? -32.409 -3.196  42.76   1   41.12  ? 266 LYS D NZ  1 
ATOM   7662 N  N   . PHE D 2 97  ? -39.527 -4.161  39.092  1   42.05  ? 267 PHE D N   1 
ATOM   7663 C  CA  . PHE D 2 97  ? -40.208 -3.668  37.909  1   41.76  ? 267 PHE D CA  1 
ATOM   7664 C  C   . PHE D 2 97  ? -41.677 -3.436  38.237  1   43.62  ? 267 PHE D C   1 
ATOM   7665 O  O   . PHE D 2 97  ? -42.215 -2.367  37.955  1   44.24  ? 267 PHE D O   1 
ATOM   7666 C  CB  . PHE D 2 97  ? -40     -4.557  36.679  1   40.93  ? 267 PHE D CB  1 
ATOM   7667 C  CG  . PHE D 2 97  ? -40.692 -4.047  35.421  1   44.58  ? 267 PHE D CG  1 
ATOM   7668 C  CD1 . PHE D 2 97  ? -40.084 -3.097  34.603  1   48.77  ? 267 PHE D CD1 1 
ATOM   7669 C  CD2 . PHE D 2 97  ? -41.959 -4.508  35.059  1   46.16  ? 267 PHE D CD2 1 
ATOM   7670 C  CE1 . PHE D 2 97  ? -40.73  -2.638  33.453  1   51.76  ? 267 PHE D CE1 1 
ATOM   7671 C  CE2 . PHE D 2 97  ? -42.604 -4.052  33.915  1   47.06  ? 267 PHE D CE2 1 
ATOM   7672 C  CZ  . PHE D 2 97  ? -41.984 -3.122  33.104  1   51.06  ? 267 PHE D CZ  1 
ATOM   7673 N  N   . GLU D 2 98  ? -42.274 -4.428  38.913  1   47.39  ? 268 GLU D N   1 
ATOM   7674 C  CA  . GLU D 2 98  ? -43.717 -4.622  38.967  1   46.87  ? 268 GLU D CA  1 
ATOM   7675 C  C   . GLU D 2 98  ? -44.324 -4.207  40.313  1   47.44  ? 268 GLU D C   1 
ATOM   7676 O  O   . GLU D 2 98  ? -45.466 -3.762  40.335  1   52.16  ? 268 GLU D O   1 
ATOM   7677 C  CB  . GLU D 2 98  ? -44.001 -6.097  38.668  1   43.42  ? 268 GLU D CB  1 
ATOM   7678 C  CG  . GLU D 2 98  ? -45.465 -6.38   38.346  1   48.62  ? 268 GLU D CG  1 
ATOM   7679 C  CD  . GLU D 2 98  ? -45.99  -5.604  37.15   1   52.68  ? 268 GLU D CD  1 
ATOM   7680 O  OE1 . GLU D 2 98  ? -45.19  -5.217  36.261  1   49.32  ? 268 GLU D OE1 1 
ATOM   7681 O  OE2 . GLU D 2 98  ? -47.217 -5.349  37.146  1   57.7   ? 268 GLU D OE2 1 
ATOM   7682 N  N   . GLU D 2 99  ? -43.606 -4.391  41.434  1   45.45  ? 269 GLU D N   1 
ATOM   7683 C  CA  . GLU D 2 99  ? -44.232 -4.309  42.748  1   45.52  ? 269 GLU D CA  1 
ATOM   7684 C  C   . GLU D 2 99  ? -44.238 -2.856  43.193  1   50.69  ? 269 GLU D C   1 
ATOM   7685 O  O   . GLU D 2 99  ? -43.273 -2.131  42.984  1   55.57  ? 269 GLU D O   1 
ATOM   7686 C  CB  . GLU D 2 99  ? -43.47  -5.128  43.792  1   45.71  ? 269 GLU D CB  1 
ATOM   7687 C  CG  . GLU D 2 99  ? -43.569 -6.644  43.619  1   49.26  ? 269 GLU D CG  1 
ATOM   7688 C  CD  . GLU D 2 99  ? -44.952 -7.272  43.8    1   55     ? 269 GLU D CD  1 
ATOM   7689 O  OE1 . GLU D 2 99  ? -45.665 -6.913  44.758  1   59.07  ? 269 GLU D OE1 1 
ATOM   7690 O  OE2 . GLU D 2 99  ? -45.34  -8.133  42.989  1   53.42  ? 269 GLU D OE2 1 
ATOM   7691 N  N   . ILE D 2 100 ? -45.325 -2.452  43.844  1   55.7   ? 270 ILE D N   1 
ATOM   7692 C  CA  . ILE D 2 100 ? -45.389 -1.19   44.566  1   54.58  ? 270 ILE D CA  1 
ATOM   7693 C  C   . ILE D 2 100 ? -44.331 -1.146  45.68   1   58.39  ? 270 ILE D C   1 
ATOM   7694 O  O   . ILE D 2 100 ? -43.628 -0.145  45.835  1   64.16  ? 270 ILE D O   1 
ATOM   7695 C  CB  . ILE D 2 100 ? -46.815 -1.005  45.111  1   53.62  ? 270 ILE D CB  1 
ATOM   7696 C  CG1 . ILE D 2 100 ? -47.854 -1.005  43.994  1   51.06  ? 270 ILE D CG1 1 
ATOM   7697 C  CG2 . ILE D 2 100 ? -46.922 0.26    45.964  1   55.62  ? 270 ILE D CG2 1 
ATOM   7698 C  CD1 . ILE D 2 100 ? -49.292 -0.962  44.499  1   47.56  ? 270 ILE D CD1 1 
ATOM   7699 N  N   . TYR D 2 101 ? -44.258 -2.223  46.478  1   57.83  ? 271 TYR D N   1 
ATOM   7700 C  CA  . TYR D 2 101 ? -43.37  -2.336  47.625  1   55.53  ? 271 TYR D CA  1 
ATOM   7701 C  C   . TYR D 2 101 ? -42.537 -3.612  47.475  1   59.33  ? 271 TYR D C   1 
ATOM   7702 O  O   . TYR D 2 101 ? -42.84  -4.644  48.087  1   59.88  ? 271 TYR D O   1 
ATOM   7703 C  CB  . TYR D 2 101 ? -44.173 -2.472  48.922  1   51.71  ? 271 TYR D CB  1 
ATOM   7704 C  CG  . TYR D 2 101 ? -45.148 -1.349  49.215  1   54.36  ? 271 TYR D CG  1 
ATOM   7705 C  CD1 . TYR D 2 101 ? -44.693 -0.105  49.635  1   54.73  ? 271 TYR D CD1 1 
ATOM   7706 C  CD2 . TYR D 2 101 ? -46.526 -1.548  49.095  1   59.93  ? 271 TYR D CD2 1 
ATOM   7707 C  CE1 . TYR D 2 101 ? -45.587 0.917   49.911  1   61.71  ? 271 TYR D CE1 1 
ATOM   7708 C  CE2 . TYR D 2 101 ? -47.429 -0.531  49.361  1   63.15  ? 271 TYR D CE2 1 
ATOM   7709 C  CZ  . TYR D 2 101 ? -46.954 0.701   49.783  1   65.9   ? 271 TYR D CZ  1 
ATOM   7710 O  OH  . TYR D 2 101 ? -47.855 1.697   50.042  1   78.48  ? 271 TYR D OH  1 
ATOM   7711 N  N   . PRO D 2 102 ? -41.463 -3.611  46.648  1   54.08  ? 272 PRO D N   1 
ATOM   7712 C  CA  . PRO D 2 102 ? -40.665 -4.826  46.468  1   49.72  ? 272 PRO D CA  1 
ATOM   7713 C  C   . PRO D 2 102 ? -40.027 -5.198  47.801  1   53.28  ? 272 PRO D C   1 
ATOM   7714 O  O   . PRO D 2 102 ? -39.778 -4.336  48.654  1   54.8   ? 272 PRO D O   1 
ATOM   7715 C  CB  . PRO D 2 102 ? -39.626 -4.454  45.422  1   45.88  ? 272 PRO D CB  1 
ATOM   7716 C  CG  . PRO D 2 102 ? -39.587 -2.938  45.492  1   48.57  ? 272 PRO D CG  1 
ATOM   7717 C  CD  . PRO D 2 102 ? -40.98  -2.47   45.857  1   48.32  ? 272 PRO D CD  1 
ATOM   7718 N  N   . PRO D 2 103 ? -39.768 -6.5    48.048  1   51.7   ? 273 PRO D N   1 
ATOM   7719 C  CA  . PRO D 2 103 ? -38.944 -6.869  49.19   1   51.75  ? 273 PRO D CA  1 
ATOM   7720 C  C   . PRO D 2 103 ? -37.569 -6.232  48.978  1   52.83  ? 273 PRO D C   1 
ATOM   7721 O  O   . PRO D 2 103 ? -37.169 -5.957  47.847  1   50.84  ? 273 PRO D O   1 
ATOM   7722 C  CB  . PRO D 2 103 ? -38.919 -8.403  49.115  1   47.9   ? 273 PRO D CB  1 
ATOM   7723 C  CG  . PRO D 2 103 ? -40.115 -8.772  48.293  1   49.67  ? 273 PRO D CG  1 
ATOM   7724 C  CD  . PRO D 2 103 ? -40.271 -7.658  47.287  1   50.21  ? 273 PRO D CD  1 
ATOM   7725 N  N   . GLU D 2 104 ? -36.851 -6.013  50.082  1   53.04  ? 274 GLU D N   1 
ATOM   7726 C  CA  . GLU D 2 104 ? -35.481 -5.541  50.027  1   55.98  ? 274 GLU D CA  1 
ATOM   7727 C  C   . GLU D 2 104 ? -34.529 -6.671  49.649  1   55.25  ? 274 GLU D C   1 
ATOM   7728 O  O   . GLU D 2 104 ? -34.834 -7.861  49.816  1   56.59  ? 274 GLU D O   1 
ATOM   7729 C  CB  . GLU D 2 104 ? -35.129 -5.002  51.412  1   63.21  ? 274 GLU D CB  1 
ATOM   7730 C  CG  . GLU D 2 104 ? -35.781 -3.66   51.715  1   70.96  ? 274 GLU D CG  1 
ATOM   7731 C  CD  . GLU D 2 104 ? -35.624 -3.344  53.183  1   86.57  ? 274 GLU D CD  1 
ATOM   7732 O  OE1 . GLU D 2 104 ? -35.962 -2.208  53.556  1   102.42 ? 274 GLU D OE1 1 
ATOM   7733 O  OE2 . GLU D 2 104 ? -35.167 -4.225  53.947  1   91.52  ? 274 GLU D OE2 1 
ATOM   7734 N  N   . VAL D 2 105 ? -33.351 -6.268  49.171  1   49.01  ? 275 VAL D N   1 
ATOM   7735 C  CA  . VAL D 2 105 ? -32.361 -7.223  48.704  1   49.12  ? 275 VAL D CA  1 
ATOM   7736 C  C   . VAL D 2 105 ? -32.067 -8.256  49.797  1   49.96  ? 275 VAL D C   1 
ATOM   7737 O  O   . VAL D 2 105 ? -31.948 -9.448  49.512  1   48.61  ? 275 VAL D O   1 
ATOM   7738 C  CB  . VAL D 2 105 ? -31.098 -6.513  48.168  1   47.21  ? 275 VAL D CB  1 
ATOM   7739 C  CG1 . VAL D 2 105 ? -29.998 -7.49   47.795  1   45.95  ? 275 VAL D CG1 1 
ATOM   7740 C  CG2 . VAL D 2 105 ? -31.404 -5.612  46.971  1   45.42  ? 275 VAL D CG2 1 
ATOM   7741 N  N   . ALA D 2 106 ? -31.974 -7.809  51.058  1   52.71  ? 276 ALA D N   1 
ATOM   7742 C  CA  . ALA D 2 106 ? -31.616 -8.718  52.142  1   55.69  ? 276 ALA D CA  1 
ATOM   7743 C  C   . ALA D 2 106 ? -32.6   -9.89   52.228  1   56.81  ? 276 ALA D C   1 
ATOM   7744 O  O   . ALA D 2 106 ? -32.227 -10.983 52.654  1   59.68  ? 276 ALA D O   1 
ATOM   7745 C  CB  . ALA D 2 106 ? -31.493 -7.99   53.475  1   48.86  ? 276 ALA D CB  1 
ATOM   7746 N  N   . GLU D 2 107 ? -33.867 -9.637  51.878  1   55.56  ? 277 GLU D N   1 
ATOM   7747 C  CA  . GLU D 2 107 ? -34.89  -10.667 51.905  1   60.49  ? 277 GLU D CA  1 
ATOM   7748 C  C   . GLU D 2 107 ? -34.602 -11.705 50.821  1   61.24  ? 277 GLU D C   1 
ATOM   7749 O  O   . GLU D 2 107 ? -34.791 -12.902 51.027  1   65.38  ? 277 GLU D O   1 
ATOM   7750 C  CB  . GLU D 2 107 ? -36.267 -10.007 51.885  1   62.78  ? 277 GLU D CB  1 
ATOM   7751 C  CG  . GLU D 2 107 ? -36.659 -9.498  53.27   1   78.62  ? 277 GLU D CG  1 
ATOM   7752 C  CD  . GLU D 2 107 ? -37.882 -8.595  53.307  1   103.54 ? 277 GLU D CD  1 
ATOM   7753 O  OE1 . GLU D 2 107 ? -38.859 -8.989  53.979  1   124.91 ? 277 GLU D OE1 1 
ATOM   7754 O  OE2 . GLU D 2 107 ? -37.871 -7.502  52.695  1   105.19 ? 277 GLU D OE2 1 
ATOM   7755 N  N   . PHE D 2 108 ? -34.043 -11.248 49.696  1   57.18  ? 278 PHE D N   1 
ATOM   7756 C  CA  . PHE D 2 108 ? -33.719 -12.138 48.6    1   50.78  ? 278 PHE D CA  1 
ATOM   7757 C  C   . PHE D 2 108 ? -32.524 -13.011 48.977  1   56.99  ? 278 PHE D C   1 
ATOM   7758 O  O   . PHE D 2 108 ? -32.393 -14.144 48.494  1   60.75  ? 278 PHE D O   1 
ATOM   7759 C  CB  . PHE D 2 108 ? -33.522 -11.335 47.314  1   46.9   ? 278 PHE D CB  1 
ATOM   7760 C  CG  . PHE D 2 108 ? -34.854 -10.952 46.697  1   52.37  ? 278 PHE D CG  1 
ATOM   7761 C  CD1 . PHE D 2 108 ? -35.566 -11.876 45.91   1   51.52  ? 278 PHE D CD1 1 
ATOM   7762 C  CD2 . PHE D 2 108 ? -35.411 -9.691  46.926  1   49.59  ? 278 PHE D CD2 1 
ATOM   7763 C  CE1 . PHE D 2 108 ? -36.79  -11.534 45.336  1   49.22  ? 278 PHE D CE1 1 
ATOM   7764 C  CE2 . PHE D 2 108 ? -36.651 -9.367  46.374  1   52.78  ? 278 PHE D CE2 1 
ATOM   7765 C  CZ  . PHE D 2 108 ? -37.329 -10.275 45.563  1   51.74  ? 278 PHE D CZ  1 
ATOM   7766 N  N   . VAL D 2 109 ? -31.628 -12.47  49.806  1   52.35  ? 279 VAL D N   1 
ATOM   7767 C  CA  . VAL D 2 109 ? -30.482 -13.246 50.248  1   57.12  ? 279 VAL D CA  1 
ATOM   7768 C  C   . VAL D 2 109 ? -30.953 -14.294 51.252  1   60.44  ? 279 VAL D C   1 
ATOM   7769 O  O   . VAL D 2 109 ? -30.48  -15.433 51.252  1   66.11  ? 279 VAL D O   1 
ATOM   7770 C  CB  . VAL D 2 109 ? -29.373 -12.375 50.866  1   54.93  ? 279 VAL D CB  1 
ATOM   7771 C  CG1 . VAL D 2 109 ? -28.26  -13.231 51.454  1   52.42  ? 279 VAL D CG1 1 
ATOM   7772 C  CG2 . VAL D 2 109 ? -28.8   -11.391 49.857  1   51.63  ? 279 VAL D CG2 1 
ATOM   7773 N  N   . TYR D 2 110 ? -31.852 -13.866 52.136  1   58.37  ? 280 TYR D N   1 
ATOM   7774 C  CA  . TYR D 2 110 ? -32.318 -14.712 53.213  1   59.96  ? 280 TYR D CA  1 
ATOM   7775 C  C   . TYR D 2 110 ? -32.963 -15.975 52.632  1   61.79  ? 280 TYR D C   1 
ATOM   7776 O  O   . TYR D 2 110 ? -32.605 -17.063 53.054  1   61.97  ? 280 TYR D O   1 
ATOM   7777 C  CB  . TYR D 2 110 ? -33.159 -13.859 54.162  1   62.87  ? 280 TYR D CB  1 
ATOM   7778 C  CG  . TYR D 2 110 ? -33.841 -14.673 55.256  1   76.83  ? 280 TYR D CG  1 
ATOM   7779 C  CD1 . TYR D 2 110 ? -33.177 -15.01  56.437  1   78.21  ? 280 TYR D CD1 1 
ATOM   7780 C  CD2 . TYR D 2 110 ? -35.16  -15.101 55.102  1   80.76  ? 280 TYR D CD2 1 
ATOM   7781 C  CE1 . TYR D 2 110 ? -33.813 -15.735 57.43   1   80.99  ? 280 TYR D CE1 1 
ATOM   7782 C  CE2 . TYR D 2 110 ? -35.796 -15.846 56.077  1   80.12  ? 280 TYR D CE2 1 
ATOM   7783 C  CZ  . TYR D 2 110 ? -35.125 -16.149 57.245  1   84.42  ? 280 TYR D CZ  1 
ATOM   7784 O  OH  . TYR D 2 110 ? -35.832 -16.868 58.165  1   97.49  ? 280 TYR D OH  1 
ATOM   7785 N  N   . ILE D 2 111 ? -33.829 -15.842 51.612  1   58.77  ? 281 ILE D N   1 
ATOM   7786 C  CA  . ILE D 2 111 ? -34.577 -16.966 51.048  1   65.05  ? 281 ILE D CA  1 
ATOM   7787 C  C   . ILE D 2 111 ? -33.693 -18.052 50.398  1   65.96  ? 281 ILE D C   1 
ATOM   7788 O  O   . ILE D 2 111 ? -34.194 -19.136 50.094  1   65.07  ? 281 ILE D O   1 
ATOM   7789 C  CB  . ILE D 2 111 ? -35.661 -16.467 50.072  1   64.15  ? 281 ILE D CB  1 
ATOM   7790 C  CG1 . ILE D 2 111 ? -35.081 -15.507 49.053  1   63.41  ? 281 ILE D CG1 1 
ATOM   7791 C  CG2 . ILE D 2 111 ? -36.827 -15.829 50.821  1   66.23  ? 281 ILE D CG2 1 
ATOM   7792 C  CD1 . ILE D 2 111 ? -35.86  -15.422 47.753  1   61.33  ? 281 ILE D CD1 1 
ATOM   7793 N  N   . THR D 2 112 ? -32.399 -17.77  50.165  1   63.77  ? 282 THR D N   1 
ATOM   7794 C  CA  . THR D 2 112 ? -31.463 -18.704 49.55   1   63.39  ? 282 THR D CA  1 
ATOM   7795 C  C   . THR D 2 112 ? -30.689 -19.467 50.62   1   68.92  ? 282 THR D C   1 
ATOM   7796 O  O   . THR D 2 112 ? -29.735 -20.167 50.265  1   71.25  ? 282 THR D O   1 
ATOM   7797 C  CB  . THR D 2 112 ? -30.476 -18.009 48.605  1   60.52  ? 282 THR D CB  1 
ATOM   7798 O  OG1 . THR D 2 112 ? -29.68  -17.123 49.384  1   59.94  ? 282 THR D OG1 1 
ATOM   7799 C  CG2 . THR D 2 112 ? -31.151 -17.233 47.494  1   57.45  ? 282 THR D CG2 1 
ATOM   7800 N  N   . ASP D 2 113 ? -31.094 -19.308 51.897  1   72.2   ? 283 ASP D N   1 
ATOM   7801 C  CA  . ASP D 2 113 ? -30.482 -19.953 53.056  1   82.07  ? 283 ASP D CA  1 
ATOM   7802 C  C   . ASP D 2 113 ? -28.989 -19.638 53.127  1   80.42  ? 283 ASP D C   1 
ATOM   7803 O  O   . ASP D 2 113 ? -28.181 -20.512 53.462  1   77.13  ? 283 ASP D O   1 
ATOM   7804 C  CB  . ASP D 2 113 ? -30.73  -21.454 53.089  1   101.6  ? 283 ASP D CB  1 
ATOM   7805 C  CG  . ASP D 2 113 ? -32.173 -21.869 53.314  1   114.18 ? 283 ASP D CG  1 
ATOM   7806 O  OD1 . ASP D 2 113 ? -33.03  -21.571 52.444  1   118.28 ? 283 ASP D OD1 1 
ATOM   7807 O  OD2 . ASP D 2 113 ? -32.419 -22.47  54.372  1   120.06 ? 283 ASP D OD2 1 
ATOM   7808 N  N   . ASP D 2 114 ? -28.647 -18.379 52.812  1   82.27  ? 284 ASP D N   1 
ATOM   7809 C  CA  . ASP D 2 114 ? -27.273 -17.9   52.773  1   90.17  ? 284 ASP D CA  1 
ATOM   7810 C  C   . ASP D 2 114 ? -26.397 -18.79  51.875  1   88.09  ? 284 ASP D C   1 
ATOM   7811 O  O   . ASP D 2 114 ? -25.191 -18.905 52.102  1   86.78  ? 284 ASP D O   1 
ATOM   7812 C  CB  . ASP D 2 114 ? -26.75  -17.658 54.185  1   103.6  ? 284 ASP D CB  1 
ATOM   7813 C  CG  . ASP D 2 114 ? -27.711 -16.936 55.122  1   101.92 ? 284 ASP D CG  1 
ATOM   7814 O  OD1 . ASP D 2 114 ? -28.262 -15.888 54.698  1   96.47  ? 284 ASP D OD1 1 
ATOM   7815 O  OD2 . ASP D 2 114 ? -27.899 -17.428 56.264  1   98.45  ? 284 ASP D OD2 1 
ATOM   7816 N  N   . THR D 2 115 ? -26.995 -19.41  50.84   1   77.6   ? 285 THR D N   1 
ATOM   7817 C  CA  . THR D 2 115 ? -26.216 -20.091 49.816  1   73.44  ? 285 THR D CA  1 
ATOM   7818 C  C   . THR D 2 115 ? -25.365 -19.043 49.09   1   72.39  ? 285 THR D C   1 
ATOM   7819 O  O   . THR D 2 115 ? -24.264 -19.33  48.625  1   69.85  ? 285 THR D O   1 
ATOM   7820 C  CB  . THR D 2 115 ? -27.116 -20.841 48.828  1   74.03  ? 285 THR D CB  1 
ATOM   7821 O  OG1 . THR D 2 115 ? -27.963 -21.774 49.492  1   77.54  ? 285 THR D OG1 1 
ATOM   7822 C  CG2 . THR D 2 115 ? -26.319 -21.589 47.773  1   65.25  ? 285 THR D CG2 1 
ATOM   7823 N  N   . TYR D 2 116 ? -25.906 -17.825 48.965  1   61.53  ? 286 TYR D N   1 
ATOM   7824 C  CA  . TYR D 2 116 ? -25.218 -16.766 48.248  1   62.19  ? 286 TYR D CA  1 
ATOM   7825 C  C   . TYR D 2 116 ? -25.04  -15.564 49.174  1   63.63  ? 286 TYR D C   1 
ATOM   7826 O  O   . TYR D 2 116 ? -25.782 -15.415 50.142  1   67.39  ? 286 TYR D O   1 
ATOM   7827 C  CB  . TYR D 2 116 ? -25.951 -16.409 46.948  1   55.18  ? 286 TYR D CB  1 
ATOM   7828 C  CG  . TYR D 2 116 ? -26.27  -17.59  46.041  1   55.72  ? 286 TYR D CG  1 
ATOM   7829 C  CD1 . TYR D 2 116 ? -25.255 -18.265 45.361  1   58.53  ? 286 TYR D CD1 1 
ATOM   7830 C  CD2 . TYR D 2 116 ? -27.584 -18.009 45.823  1   53.34  ? 286 TYR D CD2 1 
ATOM   7831 C  CE1 . TYR D 2 116 ? -25.526 -19.345 44.529  1   55.41  ? 286 TYR D CE1 1 
ATOM   7832 C  CE2 . TYR D 2 116 ? -27.869 -19.09  44.994  1   55.99  ? 286 TYR D CE2 1 
ATOM   7833 C  CZ  . TYR D 2 116 ? -26.839 -19.75  44.335  1   54.76  ? 286 TYR D CZ  1 
ATOM   7834 O  OH  . TYR D 2 116 ? -27.117 -20.787 43.49   1   56.1   ? 286 TYR D OH  1 
ATOM   7835 N  N   . THR D 2 117 ? -24.044 -14.72  48.869  1   62.44  ? 287 THR D N   1 
ATOM   7836 C  CA  . THR D 2 117 ? -23.812 -13.451 49.558  1   62.61  ? 287 THR D CA  1 
ATOM   7837 C  C   . THR D 2 117 ? -24.712 -12.374 48.956  1   59.88  ? 287 THR D C   1 
ATOM   7838 O  O   . THR D 2 117 ? -25.254 -12.571 47.87   1   60.64  ? 287 THR D O   1 
ATOM   7839 C  CB  . THR D 2 117 ? -22.341 -13.034 49.461  1   63.24  ? 287 THR D CB  1 
ATOM   7840 O  OG1 . THR D 2 117 ? -22.065 -12.629 48.12   1   69.04  ? 287 THR D OG1 1 
ATOM   7841 C  CG2 . THR D 2 117 ? -21.392 -14.146 49.861  1   58.72  ? 287 THR D CG2 1 
ATOM   7842 N  N   . LYS D 2 118 ? -24.835 -11.223 49.641  1   60.32  ? 288 LYS D N   1 
ATOM   7843 C  CA  . LYS D 2 118 ? -25.583 -10.099 49.093  1   57.54  ? 288 LYS D CA  1 
ATOM   7844 C  C   . LYS D 2 118 ? -24.919 -9.565  47.813  1   61.66  ? 288 LYS D C   1 
ATOM   7845 O  O   . LYS D 2 118 ? -25.623 -9.155  46.861  1   61.73  ? 288 LYS D O   1 
ATOM   7846 C  CB  . LYS D 2 118 ? -25.856 -9.027  50.153  1   55.01  ? 288 LYS D CB  1 
ATOM   7847 C  CG  . LYS D 2 118 ? -26.656 -7.843  49.615  1   54.94  ? 288 LYS D CG  1 
ATOM   7848 C  CD  . LYS D 2 118 ? -27.462 -7.088  50.667  1   62.54  ? 288 LYS D CD  1 
ATOM   7849 C  CE  . LYS D 2 118 ? -26.661 -6.247  51.613  1   65.01  ? 288 LYS D CE  1 
ATOM   7850 N  NZ  . LYS D 2 118 ? -27.424 -5.184  52.269  1   67.02  ? 288 LYS D NZ  1 
ATOM   7851 N  N   . LYS D 2 119 ? -23.567 -9.528  47.826  1   54.83  ? 289 LYS D N   1 
ATOM   7852 C  CA  . LYS D 2 119 ? -22.785 -9.027  46.711  1   54.29  ? 289 LYS D CA  1 
ATOM   7853 C  C   . LYS D 2 119 ? -22.988 -9.9    45.47   1   55.64  ? 289 LYS D C   1 
ATOM   7854 O  O   . LYS D 2 119 ? -23.031 -9.374  44.344  1   57.75  ? 289 LYS D O   1 
ATOM   7855 C  CB  . LYS D 2 119 ? -21.301 -8.894  47.078  1   61.58  ? 289 LYS D CB  1 
ATOM   7856 C  CG  . LYS D 2 119 ? -20.446 -8.203  46.009  1   68.22  ? 289 LYS D CG  1 
ATOM   7857 C  CD  . LYS D 2 119 ? -19.823 -6.833  46.321  1   78.49  ? 289 LYS D CD  1 
ATOM   7858 C  CE  . LYS D 2 119 ? -18.65  -6.915  47.259  1   85.22  ? 289 LYS D CE  1 
ATOM   7859 N  NZ  . LYS D 2 119 ? -17.552 -7.744  46.74   1   73.84  ? 289 LYS D NZ  1 
ATOM   7860 N  N   . GLN D 2 120 ? -23.069 -11.23  45.671  1   52.25  ? 290 GLN D N   1 
ATOM   7861 C  CA  . GLN D 2 120 ? -23.35  -12.143 44.569  1   49.89  ? 290 GLN D CA  1 
ATOM   7862 C  C   . GLN D 2 120 ? -24.716 -11.854 43.952  1   47.8   ? 290 GLN D C   1 
ATOM   7863 O  O   . GLN D 2 120 ? -24.855 -11.759 42.729  1   47.36  ? 290 GLN D O   1 
ATOM   7864 C  CB  . GLN D 2 120 ? -23.266 -13.591 45.018  1   51.41  ? 290 GLN D CB  1 
ATOM   7865 C  CG  . GLN D 2 120 ? -21.836 -14.08  45.165  1   54.04  ? 290 GLN D CG  1 
ATOM   7866 C  CD  . GLN D 2 120 ? -21.833 -15.473 45.734  1   56.63  ? 290 GLN D CD  1 
ATOM   7867 O  OE1 . GLN D 2 120 ? -22.338 -15.7   46.84   1   63.03  ? 290 GLN D OE1 1 
ATOM   7868 N  NE2 . GLN D 2 120 ? -21.348 -16.413 44.937  1   49.71  ? 290 GLN D NE2 1 
ATOM   7869 N  N   . VAL D 2 121 ? -25.71  -11.661 44.82   1   42.72  ? 291 VAL D N   1 
ATOM   7870 C  CA  . VAL D 2 121 ? -27.036 -11.298 44.363  1   43.55  ? 291 VAL D CA  1 
ATOM   7871 C  C   . VAL D 2 121 ? -27.021 -9.961  43.607  1   44.37  ? 291 VAL D C   1 
ATOM   7872 O  O   . VAL D 2 121 ? -27.629 -9.85   42.536  1   46.88  ? 291 VAL D O   1 
ATOM   7873 C  CB  . VAL D 2 121 ? -28.048 -11.344 45.528  1   45.49  ? 291 VAL D CB  1 
ATOM   7874 C  CG1 . VAL D 2 121 ? -29.404 -10.761 45.125  1   43.27  ? 291 VAL D CG1 1 
ATOM   7875 C  CG2 . VAL D 2 121 ? -28.226 -12.776 46.028  1   39.62  ? 291 VAL D CG2 1 
ATOM   7876 N  N   . LEU D 2 122 ? -26.335 -8.94   44.143  1   46.12  ? 292 LEU D N   1 
ATOM   7877 C  CA  . LEU D 2 122 ? -26.341 -7.626  43.496  1   48.38  ? 292 LEU D CA  1 
ATOM   7878 C  C   . LEU D 2 122 ? -25.586 -7.646  42.169  1   48.29  ? 292 LEU D C   1 
ATOM   7879 O  O   . LEU D 2 122 ? -26.014 -6.982  41.223  1   48.37  ? 292 LEU D O   1 
ATOM   7880 C  CB  . LEU D 2 122 ? -25.783 -6.564  44.439  1   45.08  ? 292 LEU D CB  1 
ATOM   7881 C  CG  . LEU D 2 122 ? -26.66  -6.279  45.656  1   48.27  ? 292 LEU D CG  1 
ATOM   7882 C  CD1 . LEU D 2 122 ? -25.918 -5.41   46.625  1   50.79  ? 292 LEU D CD1 1 
ATOM   7883 C  CD2 . LEU D 2 122 ? -27.998 -5.667  45.256  1   49.75  ? 292 LEU D CD2 1 
ATOM   7884 N  N   . ARG D 2 123 ? -24.465 -8.394  42.128  1   45.33  ? 293 ARG D N   1 
ATOM   7885 C  CA  . ARG D 2 123 ? -23.667 -8.537  40.923  1   45.95  ? 293 ARG D CA  1 
ATOM   7886 C  C   . ARG D 2 123 ? -24.423 -9.316  39.844  1   44.81  ? 293 ARG D C   1 
ATOM   7887 O  O   . ARG D 2 123 ? -24.325 -8.957  38.665  1   45.42  ? 293 ARG D O   1 
ATOM   7888 C  CB  . ARG D 2 123 ? -22.287 -9.109  41.239  1   50.06  ? 293 ARG D CB  1 
ATOM   7889 C  CG  . ARG D 2 123 ? -21.328 -8.018  41.681  1   55.77  ? 293 ARG D CG  1 
ATOM   7890 C  CD  . ARG D 2 123 ? -20.072 -8.634  42.264  1   77.48  ? 293 ARG D CD  1 
ATOM   7891 N  NE  . ARG D 2 123 ? -19.034 -7.595  42.307  1   103.02 ? 293 ARG D NE  1 
ATOM   7892 C  CZ  . ARG D 2 123 ? -17.935 -7.657  43.066  1   118.87 ? 293 ARG D CZ  1 
ATOM   7893 N  NH1 . ARG D 2 123 ? -17.442 -8.82   43.473  1   117.51 ? 293 ARG D NH1 1 
ATOM   7894 N  NH2 . ARG D 2 123 ? -17.304 -6.541  43.38   1   119.34 ? 293 ARG D NH2 1 
ATOM   7895 N  N   . MET D 2 124 ? -25.181 -10.352 40.252  1   42.77  ? 294 MET D N   1 
ATOM   7896 C  CA  . MET D 2 124 ? -25.966 -11.123 39.299  1   40.92  ? 294 MET D CA  1 
ATOM   7897 C  C   . MET D 2 124 ? -27.095 -10.249 38.775  1   42.96  ? 294 MET D C   1 
ATOM   7898 O  O   . MET D 2 124 ? -27.424 -10.329 37.598  1   45.42  ? 294 MET D O   1 
ATOM   7899 C  CB  . MET D 2 124 ? -26.589 -12.372 39.918  1   40.4   ? 294 MET D CB  1 
ATOM   7900 C  CG  . MET D 2 124 ? -27.418 -13.18  38.932  1   41.67  ? 294 MET D CG  1 
ATOM   7901 S  SD  . MET D 2 124 ? -26.465 -13.903 37.574  1   46.78  ? 294 MET D SD  1 
ATOM   7902 C  CE  . MET D 2 124 ? -25.649 -15.237 38.467  1   44.15  ? 294 MET D CE  1 
ATOM   7903 N  N   . GLU D 2 125 ? -27.682 -9.431  39.658  1   43.41  ? 295 GLU D N   1 
ATOM   7904 C  CA  . GLU D 2 125 ? -28.638 -8.421  39.231  1   45.23  ? 295 GLU D CA  1 
ATOM   7905 C  C   . GLU D 2 125 ? -28.094 -7.634  38.035  1   44.92  ? 295 GLU D C   1 
ATOM   7906 O  O   . GLU D 2 125 ? -28.768 -7.494  37.014  1   45.47  ? 295 GLU D O   1 
ATOM   7907 C  CB  . GLU D 2 125 ? -29.054 -7.468  40.356  1   44.41  ? 295 GLU D CB  1 
ATOM   7908 C  CG  . GLU D 2 125 ? -30.122 -6.46   39.924  1   40.92  ? 295 GLU D CG  1 
ATOM   7909 C  CD  . GLU D 2 125 ? -30.576 -5.421  40.94   1   47.97  ? 295 GLU D CD  1 
ATOM   7910 O  OE1 . GLU D 2 125 ? -29.744 -4.549  41.337  1   48.79  ? 295 GLU D OE1 1 
ATOM   7911 O  OE2 . GLU D 2 125 ? -31.776 -5.48   41.332  1   46.34  ? 295 GLU D OE2 1 
ATOM   7912 N  N   . HIS D 2 126 ? -26.872 -7.113  38.149  1   48.18  ? 296 HIS D N   1 
ATOM   7913 C  CA  . HIS D 2 126 ? -26.337 -6.256  37.089  1   52.07  ? 296 HIS D CA  1 
ATOM   7914 C  C   . HIS D 2 126 ? -26.09  -7.073  35.816  1   48.29  ? 296 HIS D C   1 
ATOM   7915 O  O   . HIS D 2 126 ? -26.384 -6.608  34.712  1   48.7   ? 296 HIS D O   1 
ATOM   7916 C  CB  . HIS D 2 126 ? -25.083 -5.485  37.535  1   51.08  ? 296 HIS D CB  1 
ATOM   7917 C  CG  . HIS D 2 126 ? -24.745 -4.283  36.699  1   56.86  ? 296 HIS D CG  1 
ATOM   7918 N  ND1 . HIS D 2 126 ? -23.682 -3.449  36.992  1   61.14  ? 296 HIS D ND1 1 
ATOM   7919 C  CD2 . HIS D 2 126 ? -25.312 -3.78   35.578  1   52.47  ? 296 HIS D CD2 1 
ATOM   7920 C  CE1 . HIS D 2 126 ? -23.635 -2.472  36.091  1   57.24  ? 296 HIS D CE1 1 
ATOM   7921 N  NE2 . HIS D 2 126 ? -24.62  -2.65   35.228  1   55.23  ? 296 HIS D NE2 1 
ATOM   7922 N  N   . LEU D 2 127 ? -25.562 -8.291  35.983  1   45.77  ? 297 LEU D N   1 
ATOM   7923 C  CA  . LEU D 2 127 ? -25.266 -9.164  34.857  1   47.93  ? 297 LEU D CA  1 
ATOM   7924 C  C   . LEU D 2 127 ? -26.549 -9.458  34.078  1   49.78  ? 297 LEU D C   1 
ATOM   7925 O  O   . LEU D 2 127 ? -26.548 -9.387  32.853  1   52.44  ? 297 LEU D O   1 
ATOM   7926 C  CB  . LEU D 2 127 ? -24.548 -10.451 35.271  1   42.72  ? 297 LEU D CB  1 
ATOM   7927 C  CG  . LEU D 2 127 ? -24.216 -11.396 34.107  1   42.12  ? 297 LEU D CG  1 
ATOM   7928 C  CD1 . LEU D 2 127 ? -23.184 -10.771 33.173  1   40.17  ? 297 LEU D CD1 1 
ATOM   7929 C  CD2 . LEU D 2 127 ? -23.696 -12.719 34.589  1   42.12  ? 297 LEU D CD2 1 
ATOM   7930 N  N   . VAL D 2 128 ? -27.642 -9.74   34.8    1   47.3   ? 298 VAL D N   1 
ATOM   7931 C  CA  . VAL D 2 128 ? -28.906 -10.052 34.16   1   46.56  ? 298 VAL D CA  1 
ATOM   7932 C  C   . VAL D 2 128 ? -29.427 -8.851  33.374  1   48.81  ? 298 VAL D C   1 
ATOM   7933 O  O   . VAL D 2 128 ? -29.975 -9.035  32.29   1   51.85  ? 298 VAL D O   1 
ATOM   7934 C  CB  . VAL D 2 128 ? -29.945 -10.57  35.161  1   46.07  ? 298 VAL D CB  1 
ATOM   7935 C  CG1 . VAL D 2 128 ? -31.337 -10.649 34.533  1   39.95  ? 298 VAL D CG1 1 
ATOM   7936 C  CG2 . VAL D 2 128 ? -29.507 -11.926 35.717  1   41.66  ? 298 VAL D CG2 1 
ATOM   7937 N  N   . LEU D 2 129 ? -29.265 -7.642  33.916  1   45.09  ? 299 LEU D N   1 
ATOM   7938 C  CA  . LEU D 2 129 ? -29.726 -6.443  33.238  1   45.75  ? 299 LEU D CA  1 
ATOM   7939 C  C   . LEU D 2 129 ? -28.99  -6.25   31.909  1   51.05  ? 299 LEU D C   1 
ATOM   7940 O  O   . LEU D 2 129 ? -29.616 -5.848  30.92   1   48.51  ? 299 LEU D O   1 
ATOM   7941 C  CB  . LEU D 2 129 ? -29.624 -5.208  34.134  1   51.14  ? 299 LEU D CB  1 
ATOM   7942 C  CG  . LEU D 2 129 ? -30.772 -4.993  35.125  1   54.21  ? 299 LEU D CG  1 
ATOM   7943 C  CD1 . LEU D 2 129 ? -30.411 -3.892  36.089  1   51.97  ? 299 LEU D CD1 1 
ATOM   7944 C  CD2 . LEU D 2 129 ? -32.082 -4.678  34.408  1   48.78  ? 299 LEU D CD2 1 
ATOM   7945 N  N   . LYS D 2 130 ? -27.685 -6.561  31.881  1   47.81  ? 300 LYS D N   1 
ATOM   7946 C  CA  . LYS D 2 130 ? -26.873 -6.326  30.695  1   49.14  ? 300 LYS D CA  1 
ATOM   7947 C  C   . LYS D 2 130 ? -27.226 -7.363  29.63   1   51.16  ? 300 LYS D C   1 
ATOM   7948 O  O   . LYS D 2 130 ? -27.309 -7.002  28.463  1   49.45  ? 300 LYS D O   1 
ATOM   7949 C  CB  . LYS D 2 130 ? -25.359 -6.352  30.965  1   55.91  ? 300 LYS D CB  1 
ATOM   7950 C  CG  . LYS D 2 130 ? -24.863 -5.567  32.166  1   65.02  ? 300 LYS D CG  1 
ATOM   7951 C  CD  . LYS D 2 130 ? -23.377 -5.215  32.141  1   74.73  ? 300 LYS D CD  1 
ATOM   7952 C  CE  . LYS D 2 130 ? -22.759 -5.305  33.517  1   94.51  ? 300 LYS D CE  1 
ATOM   7953 N  NZ  . LYS D 2 130 ? -21.634 -4.391  33.738  1   95.01  ? 300 LYS D NZ  1 
ATOM   7954 N  N   . VAL D 2 131 ? -27.439 -8.63   30.05   1   47.94  ? 301 VAL D N   1 
ATOM   7955 C  CA  . VAL D 2 131 ? -27.753 -9.741  29.167  1   45.74  ? 301 VAL D CA  1 
ATOM   7956 C  C   . VAL D 2 131 ? -29.111 -9.524  28.511  1   48.69  ? 301 VAL D C   1 
ATOM   7957 O  O   . VAL D 2 131 ? -29.276 -9.895  27.358  1   50.94  ? 301 VAL D O   1 
ATOM   7958 C  CB  . VAL D 2 131 ? -27.64  -11.121 29.843  1   46.34  ? 301 VAL D CB  1 
ATOM   7959 C  CG1 . VAL D 2 131 ? -28.376 -12.239 29.097  1   39.69  ? 301 VAL D CG1 1 
ATOM   7960 C  CG2 . VAL D 2 131 ? -26.181 -11.492 30.099  1   44.68  ? 301 VAL D CG2 1 
ATOM   7961 N  N   . LEU D 2 132 ? -30.065 -8.932  29.239  1   50.44  ? 302 LEU D N   1 
ATOM   7962 C  CA  . LEU D 2 132 ? -31.4   -8.665  28.713  1   48.8   ? 302 LEU D CA  1 
ATOM   7963 C  C   . LEU D 2 132 ? -31.478 -7.268  28.097  1   50.34  ? 302 LEU D C   1 
ATOM   7964 O  O   . LEU D 2 132 ? -32.522 -6.899  27.566  1   52.9   ? 302 LEU D O   1 
ATOM   7965 C  CB  . LEU D 2 132 ? -32.416 -8.812  29.843  1   46.38  ? 302 LEU D CB  1 
ATOM   7966 C  CG  . LEU D 2 132 ? -32.431 -10.182 30.526  1   52.51  ? 302 LEU D CG  1 
ATOM   7967 C  CD1 . LEU D 2 132 ? -33.559 -10.285 31.541  1   49.56  ? 302 LEU D CD1 1 
ATOM   7968 C  CD2 . LEU D 2 132 ? -32.519 -11.314 29.497  1   56.23  ? 302 LEU D CD2 1 
ATOM   7969 N  N   . ALA D 2 133 ? -30.396 -6.488  28.228  1   51.4   ? 303 ALA D N   1 
ATOM   7970 C  CA  . ALA D 2 133 ? -30.277 -5.111  27.754  1   54.8   ? 303 ALA D CA  1 
ATOM   7971 C  C   . ALA D 2 133 ? -31.424 -4.241  28.265  1   54.09  ? 303 ALA D C   1 
ATOM   7972 O  O   . ALA D 2 133 ? -31.915 -3.407  27.514  1   53.91  ? 303 ALA D O   1 
ATOM   7973 C  CB  . ALA D 2 133 ? -30.117 -5.057  26.241  1   45.88  ? 303 ALA D CB  1 
ATOM   7974 N  N   . PHE D 2 134 ? -31.802 -4.421  29.546  1   50.11  ? 304 PHE D N   1 
ATOM   7975 C  CA  . PHE D 2 134 ? -32.851 -3.654  30.209  1   53.86  ? 304 PHE D CA  1 
ATOM   7976 C  C   . PHE D 2 134 ? -34.216 -3.867  29.557  1   52.2   ? 304 PHE D C   1 
ATOM   7977 O  O   . PHE D 2 134 ? -35.137 -3.1    29.812  1   53.45  ? 304 PHE D O   1 
ATOM   7978 C  CB  . PHE D 2 134 ? -32.503 -2.158  30.295  1   52.95  ? 304 PHE D CB  1 
ATOM   7979 C  CG  . PHE D 2 134 ? -31.608 -1.757  31.456  1   59.07  ? 304 PHE D CG  1 
ATOM   7980 C  CD1 . PHE D 2 134 ? -32.17  -1.39   32.678  1   55.12  ? 304 PHE D CD1 1 
ATOM   7981 C  CD2 . PHE D 2 134 ? -30.217 -1.742  31.321  1   58.04  ? 304 PHE D CD2 1 
ATOM   7982 C  CE1 . PHE D 2 134 ? -31.349 -1.01   33.732  1   55.64  ? 304 PHE D CE1 1 
ATOM   7983 C  CE2 . PHE D 2 134 ? -29.403 -1.397  32.394  1   54.81  ? 304 PHE D CE2 1 
ATOM   7984 C  CZ  . PHE D 2 134 ? -29.972 -1.022  33.592  1   54.83  ? 304 PHE D CZ  1 
ATOM   7985 N  N   A ASP D 2 135 ? -34.332 -4.873  28.68   0.5 56.73  ? 305 ASP D N   1 
ATOM   7986 N  N   B ASP D 2 135 ? -34.324 -4.851  28.657  0.5 59.79  ? 305 ASP D N   1 
ATOM   7987 C  CA  A ASP D 2 135 ? -35.605 -5.174  28.038  0.5 55.55  ? 305 ASP D CA  1 
ATOM   7988 C  CA  B ASP D 2 135 ? -35.602 -5.127  28.018  0.5 61.11  ? 305 ASP D CA  1 
ATOM   7989 C  C   A ASP D 2 135 ? -36.434 -6.018  28.992  0.5 54.9   ? 305 ASP D C   1 
ATOM   7990 C  C   B ASP D 2 135 ? -36.403 -5.99   28.987  0.5 58.07  ? 305 ASP D C   1 
ATOM   7991 O  O   A ASP D 2 135 ? -36.453 -7.241  28.878  0.5 55.65  ? 305 ASP D O   1 
ATOM   7992 O  O   B ASP D 2 135 ? -36.333 -7.212  28.91   0.5 58.7   ? 305 ASP D O   1 
ATOM   7993 C  CB  A ASP D 2 135 ? -35.438 -5.756  26.643  0.5 52.65  ? 305 ASP D CB  1 
ATOM   7994 C  CB  B ASP D 2 135 ? -35.435 -5.714  26.623  0.5 63.3   ? 305 ASP D CB  1 
ATOM   7995 C  CG  A ASP D 2 135 ? -35.095 -4.699  25.606  0.5 54.63  ? 305 ASP D CG  1 
ATOM   7996 C  CG  B ASP D 2 135 ? -36.612 -5.469  25.692  0.5 72.15  ? 305 ASP D CG  1 
ATOM   7997 O  OD1 A ASP D 2 135 ? -35.713 -3.608  25.685  0.5 62.97  ? 305 ASP D OD1 1 
ATOM   7998 O  OD1 B ASP D 2 135 ? -36.875 -4.288  25.38   0.5 85.07  ? 305 ASP D OD1 1 
ATOM   7999 O  OD2 A ASP D 2 135 ? -34.202 -4.952  24.769  0.5 51.25  ? 305 ASP D OD2 1 
ATOM   8000 O  OD2 B ASP D 2 135 ? -37.275 -6.441  25.299  0.5 68.76  ? 305 ASP D OD2 1 
ATOM   8001 N  N   . LEU D 2 136 ? -37.075 -5.337  29.949  1   53.48  ? 306 LEU D N   1 
ATOM   8002 C  CA  . LEU D 2 136 ? -37.768 -6.027  31.025  1   51.29  ? 306 LEU D CA  1 
ATOM   8003 C  C   . LEU D 2 136 ? -39.288 -6.024  30.863  1   49.87  ? 306 LEU D C   1 
ATOM   8004 O  O   . LEU D 2 136 ? -39.939 -6.838  31.506  1   52.62  ? 306 LEU D O   1 
ATOM   8005 C  CB  . LEU D 2 136 ? -37.388 -5.464  32.39   1   56.03  ? 306 LEU D CB  1 
ATOM   8006 C  CG  . LEU D 2 136 ? -35.919 -5.534  32.821  1   61.14  ? 306 LEU D CG  1 
ATOM   8007 C  CD1 . LEU D 2 136 ? -35.856 -5.401  34.336  1   70.44  ? 306 LEU D CD1 1 
ATOM   8008 C  CD2 . LEU D 2 136 ? -35.202 -6.794  32.416  1   56.07  ? 306 LEU D CD2 1 
ATOM   8009 N  N   . ALA D 2 137 ? -39.861 -5.1    30.08   1   47.48  ? 307 ALA D N   1 
ATOM   8010 C  CA  . ALA D 2 137 ? -41.315 -5.015  30.01   1   49.05  ? 307 ALA D CA  1 
ATOM   8011 C  C   . ALA D 2 137 ? -41.887 -6.1    29.084  1   49.17  ? 307 ALA D C   1 
ATOM   8012 O  O   . ALA D 2 137 ? -42.485 -5.795  28.058  1   49.2   ? 307 ALA D O   1 
ATOM   8013 C  CB  . ALA D 2 137 ? -41.748 -3.618  29.62   1   44.53  ? 307 ALA D CB  1 
ATOM   8014 N  N   . ALA D 2 138 ? -41.767 -7.368  29.499  1   48.69  ? 308 ALA D N   1 
ATOM   8015 C  CA  . ALA D 2 138 ? -42.134 -8.534  28.701  1   49.4   ? 308 ALA D CA  1 
ATOM   8016 C  C   . ALA D 2 138 ? -43.613 -8.825  28.862  1   53.35  ? 308 ALA D C   1 
ATOM   8017 O  O   . ALA D 2 138 ? -44.116 -8.865  29.976  1   60.62  ? 308 ALA D O   1 
ATOM   8018 C  CB  . ALA D 2 138 ? -41.334 -9.771  29.091  1   44.1   ? 308 ALA D CB  1 
ATOM   8019 N  N   . PRO D 2 139 ? -44.348 -9.091  27.763  1   53.46  ? 309 PRO D N   1 
ATOM   8020 C  CA  . PRO D 2 139 ? -45.735 -9.53   27.886  1   54.85  ? 309 PRO D CA  1 
ATOM   8021 C  C   . PRO D 2 139 ? -45.726 -10.93  28.493  1   57.42  ? 309 PRO D C   1 
ATOM   8022 O  O   . PRO D 2 139 ? -44.884 -11.765 28.129  1   56.46  ? 309 PRO D O   1 
ATOM   8023 C  CB  . PRO D 2 139 ? -46.288 -9.491  26.443  1   53.62  ? 309 PRO D CB  1 
ATOM   8024 C  CG  . PRO D 2 139 ? -45.221 -8.761  25.624  1   52.92  ? 309 PRO D CG  1 
ATOM   8025 C  CD  . PRO D 2 139 ? -43.901 -8.978  26.364  1   51.84  ? 309 PRO D CD  1 
ATOM   8026 N  N   . THR D 2 140 ? -46.677 -11.148 29.421  1   56.84  ? 310 THR D N   1 
ATOM   8027 C  CA  . THR D 2 140 ? -46.834 -12.409 30.136  1   53.94  ? 310 THR D CA  1 
ATOM   8028 C  C   . THR D 2 140 ? -48.141 -13.09  29.734  1   56.25  ? 310 THR D C   1 
ATOM   8029 O  O   . THR D 2 140 ? -49.004 -12.49  29.081  1   58.66  ? 310 THR D O   1 
ATOM   8030 C  CB  . THR D 2 140 ? -46.812 -12.148 31.643  1   52.29  ? 310 THR D CB  1 
ATOM   8031 O  OG1 . THR D 2 140 ? -47.959 -11.362 31.97   1   51.86  ? 310 THR D OG1 1 
ATOM   8032 C  CG2 . THR D 2 140 ? -45.55  -11.435 32.091  1   48.94  ? 310 THR D CG2 1 
ATOM   8033 N  N   . ILE D 2 141 ? -48.281 -14.349 30.158  1   53.8   ? 311 ILE D N   1 
ATOM   8034 C  CA  . ILE D 2 141 ? -49.56  -15.039 30.097  1   56.04  ? 311 ILE D CA  1 
ATOM   8035 C  C   . ILE D 2 141 ? -50.644 -14.186 30.755  1   59.2   ? 311 ILE D C   1 
ATOM   8036 O  O   . ILE D 2 141 ? -51.719 -14.019 30.178  1   63.13  ? 311 ILE D O   1 
ATOM   8037 C  CB  . ILE D 2 141 ? -49.446 -16.446 30.707  1   54.88  ? 311 ILE D CB  1 
ATOM   8038 C  CG1 . ILE D 2 141 ? -48.654 -17.368 29.786  1   54.88  ? 311 ILE D CG1 1 
ATOM   8039 C  CG2 . ILE D 2 141 ? -50.819 -17.026 31.056  1   52.16  ? 311 ILE D CG2 1 
ATOM   8040 C  CD1 . ILE D 2 141 ? -48.071 -18.563 30.512  1   56.68  ? 311 ILE D CD1 1 
ATOM   8041 N  N   . ASN D 2 142 ? -50.35  -13.629 31.941  1   58.52  ? 312 ASN D N   1 
ATOM   8042 C  CA  . ASN D 2 142 ? -51.358 -12.921 32.719  1   60.56  ? 312 ASN D CA  1 
ATOM   8043 C  C   . ASN D 2 142 ? -51.837 -11.672 31.988  1   59.91  ? 312 ASN D C   1 
ATOM   8044 O  O   . ASN D 2 142 ? -53.001 -11.31  32.15   1   63.32  ? 312 ASN D O   1 
ATOM   8045 C  CB  . ASN D 2 142 ? -50.973 -12.668 34.178  1   60.68  ? 312 ASN D CB  1 
ATOM   8046 C  CG  . ASN D 2 142 ? -50.907 -13.945 34.988  1   71.47  ? 312 ASN D CG  1 
ATOM   8047 O  OD1 . ASN D 2 142 ? -50.67  -15.034 34.444  1   87.94  ? 312 ASN D OD1 1 
ATOM   8048 N  ND2 . ASN D 2 142 ? -51.061 -13.837 36.296  1   68.72  ? 312 ASN D ND2 1 
ATOM   8049 N  N   . GLN D 2 143 ? -50.965 -11.028 31.192  1   58.18  ? 313 GLN D N   1 
ATOM   8050 C  CA  . GLN D 2 143 ? -51.319 -9.785  30.504  1   58.09  ? 313 GLN D CA  1 
ATOM   8051 C  C   . GLN D 2 143 ? -52.321 -10.05  29.382  1   62.88  ? 313 GLN D C   1 
ATOM   8052 O  O   . GLN D 2 143 ? -53.049 -9.133  28.989  1   67.77  ? 313 GLN D O   1 
ATOM   8053 C  CB  . GLN D 2 143 ? -50.128 -9.042  29.905  1   54.2   ? 313 GLN D CB  1 
ATOM   8054 C  CG  . GLN D 2 143 ? -49.347 -8.203  30.908  1   53.85  ? 313 GLN D CG  1 
ATOM   8055 C  CD  . GLN D 2 143 ? -48.075 -7.641  30.318  1   57.15  ? 313 GLN D CD  1 
ATOM   8056 O  OE1 . GLN D 2 143 ? -48.094 -6.781  29.421  1   58.88  ? 313 GLN D OE1 1 
ATOM   8057 N  NE2 . GLN D 2 143 ? -46.953 -8.154  30.805  1   55.28  ? 313 GLN D NE2 1 
ATOM   8058 N  N   . PHE D 2 144 ? -52.322 -11.291 28.857  1   60.47  ? 314 PHE D N   1 
ATOM   8059 C  CA  . PHE D 2 144 ? -53.301 -11.714 27.866  1   63.51  ? 314 PHE D CA  1 
ATOM   8060 C  C   . PHE D 2 144 ? -54.574 -12.231 28.544  1   66.21  ? 314 PHE D C   1 
ATOM   8061 O  O   . PHE D 2 144 ? -55.68  -11.856 28.14   1   66.01  ? 314 PHE D O   1 
ATOM   8062 C  CB  . PHE D 2 144 ? -52.735 -12.698 26.847  1   61.19  ? 314 PHE D CB  1 
ATOM   8063 C  CG  . PHE D 2 144 ? -51.728 -12.096 25.888  1   57.78  ? 314 PHE D CG  1 
ATOM   8064 C  CD1 . PHE D 2 144 ? -52.158 -11.329 24.811  1   59.43  ? 314 PHE D CD1 1 
ATOM   8065 C  CD2 . PHE D 2 144 ? -50.365 -12.33  26.047  1   53.44  ? 314 PHE D CD2 1 
ATOM   8066 C  CE1 . PHE D 2 144 ? -51.234 -10.79  23.922  1   59.54  ? 314 PHE D CE1 1 
ATOM   8067 C  CE2 . PHE D 2 144 ? -49.45  -11.808 25.141  1   53.81  ? 314 PHE D CE2 1 
ATOM   8068 C  CZ  . PHE D 2 144 ? -49.879 -11.029 24.088  1   54.85  ? 314 PHE D CZ  1 
ATOM   8069 N  N   . LEU D 2 145 ? -54.415 -13.061 29.585  1   63.59  ? 315 LEU D N   1 
ATOM   8070 C  CA  . LEU D 2 145 ? -55.547 -13.547 30.368  1   68.59  ? 315 LEU D CA  1 
ATOM   8071 C  C   . LEU D 2 145 ? -56.466 -12.401 30.802  1   71.78  ? 315 LEU D C   1 
ATOM   8072 O  O   . LEU D 2 145 ? -57.671 -12.463 30.544  1   76.66  ? 315 LEU D O   1 
ATOM   8073 C  CB  . LEU D 2 145 ? -55.091 -14.354 31.584  1   69.08  ? 315 LEU D CB  1 
ATOM   8074 C  CG  . LEU D 2 145 ? -54.644 -15.796 31.342  1   65.85  ? 315 LEU D CG  1 
ATOM   8075 C  CD1 . LEU D 2 145 ? -54.326 -16.431 32.685  1   67.19  ? 315 LEU D CD1 1 
ATOM   8076 C  CD2 . LEU D 2 145 ? -55.707 -16.565 30.613  1   65.66  ? 315 LEU D CD2 1 
ATOM   8077 N  N   . THR D 2 146 ? -55.91  -11.368 31.469  1   66.25  ? 316 THR D N   1 
ATOM   8078 C  CA  . THR D 2 146 ? -56.753 -10.349 32.084  1   66.16  ? 316 THR D CA  1 
ATOM   8079 C  C   . THR D 2 146 ? -57.576 -9.658  31.004  1   70.81  ? 316 THR D C   1 
ATOM   8080 O  O   . THR D 2 146 ? -58.703 -9.229  31.287  1   75.42  ? 316 THR D O   1 
ATOM   8081 C  CB  . THR D 2 146 ? -55.99  -9.34   32.945  1   63.84  ? 316 THR D CB  1 
ATOM   8082 O  OG1 . THR D 2 146 ? -55.168 -8.544  32.097  1   65.63  ? 316 THR D OG1 1 
ATOM   8083 C  CG2 . THR D 2 146 ? -55.156 -9.983  34.04   1   60.25  ? 316 THR D CG2 1 
ATOM   8084 N  N   . GLN D 2 147 ? -56.996 -9.558  29.793  1   70.03  ? 317 GLN D N   1 
ATOM   8085 C  CA  . GLN D 2 147 ? -57.654 -8.938  28.648  1   72.85  ? 317 GLN D CA  1 
ATOM   8086 C  C   . GLN D 2 147 ? -58.716 -9.861  28.047  1   76.41  ? 317 GLN D C   1 
ATOM   8087 O  O   . GLN D 2 147 ? -59.667 -9.371  27.428  1   78.54  ? 317 GLN D O   1 
ATOM   8088 C  CB  . GLN D 2 147 ? -56.665 -8.625  27.53   1   70.98  ? 317 GLN D CB  1 
ATOM   8089 C  CG  . GLN D 2 147 ? -55.927 -7.303  27.673  1   73.84  ? 317 GLN D CG  1 
ATOM   8090 C  CD  . GLN D 2 147 ? -55.087 -7.014  26.454  1   74.16  ? 317 GLN D CD  1 
ATOM   8091 O  OE1 . GLN D 2 147 ? -54.276 -6.086  26.409  1   83.27  ? 317 GLN D OE1 1 
ATOM   8092 N  NE2 . GLN D 2 147 ? -55.285 -7.819  25.432  1   75.75  ? 317 GLN D NE2 1 
ATOM   8093 N  N   . TYR D 2 148 ? -58.502 -11.183 28.181  1   78.47  ? 318 TYR D N   1 
ATOM   8094 C  CA  . TYR D 2 148 ? -59.396 -12.21  27.663  1   77.16  ? 318 TYR D CA  1 
ATOM   8095 C  C   . TYR D 2 148 ? -60.576 -12.344 28.623  1   79.48  ? 318 TYR D C   1 
ATOM   8096 O  O   . TYR D 2 148 ? -61.69  -12.652 28.194  1   78.21  ? 318 TYR D O   1 
ATOM   8097 C  CB  . TYR D 2 148 ? -58.71  -13.572 27.537  1   71.81  ? 318 TYR D CB  1 
ATOM   8098 C  CG  . TYR D 2 148 ? -57.621 -13.737 26.49   1   70.82  ? 318 TYR D CG  1 
ATOM   8099 C  CD1 . TYR D 2 148 ? -57.449 -12.822 25.454  1   69.72  ? 318 TYR D CD1 1 
ATOM   8100 C  CD2 . TYR D 2 148 ? -56.772 -14.847 26.534  1   70.52  ? 318 TYR D CD2 1 
ATOM   8101 C  CE1 . TYR D 2 148 ? -56.461 -13.021 24.495  1   70.89  ? 318 TYR D CE1 1 
ATOM   8102 C  CE2 . TYR D 2 148 ? -55.778 -15.049 25.588  1   65.92  ? 318 TYR D CE2 1 
ATOM   8103 C  CZ  . TYR D 2 148 ? -55.625 -14.13  24.569  1   68.85  ? 318 TYR D CZ  1 
ATOM   8104 O  OH  . TYR D 2 148 ? -54.627 -14.334 23.667  1   76.21  ? 318 TYR D OH  1 
ATOM   8105 N  N   . PHE D 2 149 ? -60.318 -12.062 29.907  1   76.88  ? 319 PHE D N   1 
ATOM   8106 C  CA  . PHE D 2 149 ? -61.342 -12.111 30.933  1   83.12  ? 319 PHE D CA  1 
ATOM   8107 C  C   . PHE D 2 149 ? -62.408 -11.037 30.7    1   91.2   ? 319 PHE D C   1 
ATOM   8108 O  O   . PHE D 2 149 ? -63.474 -11.097 31.309  1   100.55 ? 319 PHE D O   1 
ATOM   8109 C  CB  . PHE D 2 149 ? -60.755 -11.977 32.341  1   84.02  ? 319 PHE D CB  1 
ATOM   8110 C  CG  . PHE D 2 149 ? -59.854 -13.1   32.825  1   86.48  ? 319 PHE D CG  1 
ATOM   8111 C  CD1 . PHE D 2 149 ? -59.81  -14.323 32.151  1   90.94  ? 319 PHE D CD1 1 
ATOM   8112 C  CD2 . PHE D 2 149 ? -59.083 -12.934 33.974  1   81.44  ? 319 PHE D CD2 1 
ATOM   8113 C  CE1 . PHE D 2 149 ? -58.995 -15.351 32.609  1   94.54  ? 319 PHE D CE1 1 
ATOM   8114 C  CE2 . PHE D 2 149 ? -58.267 -13.963 34.43   1   87.65  ? 319 PHE D CE2 1 
ATOM   8115 C  CZ  . PHE D 2 149 ? -58.218 -15.167 33.744  1   93.36  ? 319 PHE D CZ  1 
ATOM   8116 N  N   . LEU D 2 150 ? -62.147 -10.077 29.802  1   90.2   ? 320 LEU D N   1 
ATOM   8117 C  CA  . LEU D 2 150 ? -63.09  -8.995  29.535  1   90.72  ? 320 LEU D CA  1 
ATOM   8118 C  C   . LEU D 2 150 ? -64.184 -9.402  28.536  1   91.71  ? 320 LEU D C   1 
ATOM   8119 O  O   . LEU D 2 150 ? -65.189 -8.706  28.408  1   95.1   ? 320 LEU D O   1 
ATOM   8120 C  CB  . LEU D 2 150 ? -62.345 -7.739  29.068  1   86.97  ? 320 LEU D CB  1 
ATOM   8121 C  CG  . LEU D 2 150 ? -61.418 -7.037  30.072  1   83.41  ? 320 LEU D CG  1 
ATOM   8122 C  CD1 . LEU D 2 150 ? -60.933 -5.755  29.42   1   75.85  ? 320 LEU D CD1 1 
ATOM   8123 C  CD2 . LEU D 2 150 ? -62.064 -6.727  31.419  1   86.42  ? 320 LEU D CD2 1 
ATOM   8124 N  N   . HIS D 2 151 ? -63.981 -10.499 27.795  1   90.85  ? 321 HIS D N   1 
ATOM   8125 C  CA  . HIS D 2 151 ? -64.957 -10.976 26.827  1   90.32  ? 321 HIS D CA  1 
ATOM   8126 C  C   . HIS D 2 151 ? -65.999 -11.891 27.481  1   90.01  ? 321 HIS D C   1 
ATOM   8127 O  O   . HIS D 2 151 ? -66.993 -12.225 26.844  1   90.63  ? 321 HIS D O   1 
ATOM   8128 C  CB  . HIS D 2 151 ? -64.251 -11.563 25.598  1   93.6   ? 321 HIS D CB  1 
ATOM   8129 C  CG  . HIS D 2 151 ? -63.582 -10.534 24.745  1   96.61  ? 321 HIS D CG  1 
ATOM   8130 N  ND1 . HIS D 2 151 ? -63.702 -10.524 23.366  1   99.53  ? 321 HIS D ND1 1 
ATOM   8131 C  CD2 . HIS D 2 151 ? -62.809 -9.48   25.067  1   92.2   ? 321 HIS D CD2 1 
ATOM   8132 C  CE1 . HIS D 2 151 ? -63.017 -9.495  22.881  1   99.4   ? 321 HIS D CE1 1 
ATOM   8133 N  NE2 . HIS D 2 151 ? -62.468 -8.846  23.9    1   93.5   ? 321 HIS D NE2 1 
ATOM   8134 N  N   . GLN D 2 152 ? -65.796 -12.273 28.754  1   90.39  ? 322 GLN D N   1 
ATOM   8135 C  CA  . GLN D 2 152 ? -66.791 -13.032 29.504  1   96.29  ? 322 GLN D CA  1 
ATOM   8136 C  C   . GLN D 2 152 ? -68.105 -12.257 29.55   1   106.03 ? 322 GLN D C   1 
ATOM   8137 O  O   . GLN D 2 152 ? -68.13  -11.055 29.31   1   108.82 ? 322 GLN D O   1 
ATOM   8138 C  CB  . GLN D 2 152 ? -66.358 -13.235 30.95   1   97.3   ? 322 GLN D CB  1 
ATOM   8139 C  CG  . GLN D 2 152 ? -65.508 -14.473 31.197  1   99.76  ? 322 GLN D CG  1 
ATOM   8140 C  CD  . GLN D 2 152 ? -64.875 -14.42  32.568  1   103.38 ? 322 GLN D CD  1 
ATOM   8141 O  OE1 . GLN D 2 152 ? -65.043 -15.322 33.391  1   108.06 ? 322 GLN D OE1 1 
ATOM   8142 N  NE2 . GLN D 2 152 ? -64.165 -13.333 32.839  1   97.65  ? 322 GLN D NE2 1 
ATOM   8143 N  N   . GLN D 2 153 ? -69.196 -12.959 29.882  1   118.92 ? 323 GLN D N   1 
ATOM   8144 C  CA  . GLN D 2 153 ? -70.538 -12.392 29.905  1   121.4  ? 323 GLN D CA  1 
ATOM   8145 C  C   . GLN D 2 153 ? -71.488 -13.451 30.46   1   121.12 ? 323 GLN D C   1 
ATOM   8146 O  O   . GLN D 2 153 ? -72.189 -14.105 29.696  1   126.1  ? 323 GLN D O   1 
ATOM   8147 C  CB  . GLN D 2 153 ? -70.921 -12.054 28.467  1   127.98 ? 323 GLN D CB  1 
ATOM   8148 C  CG  . GLN D 2 153 ? -71.557 -10.683 28.316  1   138.67 ? 323 GLN D CG  1 
ATOM   8149 C  CD  . GLN D 2 153 ? -71.823 -10.328 26.872  1   147.87 ? 323 GLN D CD  1 
ATOM   8150 O  OE1 . GLN D 2 153 ? -71.903 -11.187 25.985  1   149.54 ? 323 GLN D OE1 1 
ATOM   8151 N  NE2 . GLN D 2 153 ? -71.963 -9.038  26.626  1   150.8  ? 323 GLN D NE2 1 
ATOM   8152 N  N   . PRO D 2 154 ? -71.533 -13.691 31.793  1   119.27 ? 324 PRO D N   1 
ATOM   8153 C  CA  . PRO D 2 154 ? -70.966 -12.795 32.811  1   116.02 ? 324 PRO D CA  1 
ATOM   8154 C  C   . PRO D 2 154 ? -69.543 -13.208 33.19   1   119.32 ? 324 PRO D C   1 
ATOM   8155 O  O   . PRO D 2 154 ? -68.977 -14.086 32.539  1   125.93 ? 324 PRO D O   1 
ATOM   8156 C  CB  . PRO D 2 154 ? -71.944 -13.085 33.948  1   114.8  ? 324 PRO D CB  1 
ATOM   8157 C  CG  . PRO D 2 154 ? -72.171 -14.585 33.859  1   117.36 ? 324 PRO D CG  1 
ATOM   8158 C  CD  . PRO D 2 154 ? -72.096 -14.918 32.383  1   119.49 ? 324 PRO D CD  1 
ATOM   8159 N  N   . ALA D 2 155 ? -68.975 -12.595 34.244  1   112.42 ? 325 ALA D N   1 
ATOM   8160 C  CA  . ALA D 2 155 ? -67.616 -12.884 34.676  1   102    ? 325 ALA D CA  1 
ATOM   8161 C  C   . ALA D 2 155 ? -67.639 -13.894 35.829  1   105.29 ? 325 ALA D C   1 
ATOM   8162 O  O   . ALA D 2 155 ? -68.267 -13.638 36.853  1   110.16 ? 325 ALA D O   1 
ATOM   8163 C  CB  . ALA D 2 155 ? -66.948 -11.583 35.059  1   89.02  ? 325 ALA D CB  1 
ATOM   8164 N  N   . ASN D 2 156 ? -66.993 -15.059 35.646  1   103.39 ? 326 ASN D N   1 
ATOM   8165 C  CA  . ASN D 2 156 ? -66.938 -16.083 36.681  1   105.13 ? 326 ASN D CA  1 
ATOM   8166 C  C   . ASN D 2 156 ? -65.592 -15.982 37.389  1   103.6  ? 326 ASN D C   1 
ATOM   8167 O  O   . ASN D 2 156 ? -64.549 -15.986 36.737  1   95.67  ? 326 ASN D O   1 
ATOM   8168 C  CB  . ASN D 2 156 ? -67.135 -17.497 36.132  1   106.93 ? 326 ASN D CB  1 
ATOM   8169 C  CG  . ASN D 2 156 ? -67.528 -18.506 37.183  1   109.63 ? 326 ASN D CG  1 
ATOM   8170 O  OD1 . ASN D 2 156 ? -66.937 -18.546 38.266  1   109.4  ? 326 ASN D OD1 1 
ATOM   8171 N  ND2 . ASN D 2 156 ? -68.551 -19.299 36.896  1   115.6  ? 326 ASN D ND2 1 
ATOM   8172 N  N   . CYS D 2 157 ? -65.65  -15.904 38.725  1   107.11 ? 327 CYS D N   1 
ATOM   8173 C  CA  . CYS D 2 157 ? -64.496 -15.888 39.608  1   104.13 ? 327 CYS D CA  1 
ATOM   8174 C  C   . CYS D 2 157 ? -63.727 -17.197 39.477  1   103.52 ? 327 CYS D C   1 
ATOM   8175 O  O   . CYS D 2 157 ? -62.548 -17.252 39.829  1   100.48 ? 327 CYS D O   1 
ATOM   8176 C  CB  . CYS D 2 157 ? -64.946 -15.825 41.061  1   111.71 ? 327 CYS D CB  1 
ATOM   8177 S  SG  . CYS D 2 157 ? -65.818 -14.298 41.492  1   137.79 ? 327 CYS D SG  1 
ATOM   8178 N  N   . LYS D 2 158 ? -64.395 -18.26  39.046  1   104.72 ? 328 LYS D N   1 
ATOM   8179 C  CA  . LYS D 2 158 ? -63.694 -19.569 39.028  1   103.19 ? 328 LYS D CA  1 
ATOM   8180 C  C   . LYS D 2 158 ? -63.046 -19.748 37.655  1   101.42 ? 328 LYS D C   1 
ATOM   8181 O  O   . LYS D 2 158 ? -61.887 -20.187 37.604  1   100.32 ? 328 LYS D O   1 
ATOM   8182 C  CB  . LYS D 2 158 ? -64.661 -20.696 39.394  1   111.4  ? 328 LYS D CB  1 
ATOM   8183 C  CG  . LYS D 2 158 ? -65.191 -20.622 40.814  1   110.84 ? 328 LYS D CG  1 
ATOM   8184 C  CD  . LYS D 2 158 ? -66.147 -21.762 41.132  1   106.16 ? 328 LYS D CD  1 
ATOM   8185 C  CE  . LYS D 2 158 ? -66.701 -21.656 42.515  1   109    ? 328 LYS D CE  1 
ATOM   8186 N  NZ  . LYS D 2 158 ? -65.65  -21.76  43.531  1   110.72 ? 328 LYS D NZ  1 
ATOM   8187 N  N   . VAL D 2 159 ? -63.76  -19.391 36.594  1   97.28  ? 329 VAL D N   1 
ATOM   8188 C  CA  . VAL D 2 159 ? -63.138 -19.445 35.246  1   94.25  ? 329 VAL D CA  1 
ATOM   8189 C  C   . VAL D 2 159 ? -61.814 -18.677 35.33   1   95.61  ? 329 VAL D C   1 
ATOM   8190 O  O   . VAL D 2 159 ? -60.792 -19.209 34.865  1   99.27  ? 329 VAL D O   1 
ATOM   8191 C  CB  . VAL D 2 159 ? -64.074 -18.838 34.188  1   88.82  ? 329 VAL D CB  1 
ATOM   8192 C  CG1 . VAL D 2 159 ? -63.323 -18.402 32.937  1   84.22  ? 329 VAL D CG1 1 
ATOM   8193 C  CG2 . VAL D 2 159 ? -65.206 -19.79  33.834  1   96.71  ? 329 VAL D CG2 1 
ATOM   8194 N  N   . GLU D 2 160 ? -61.832 -17.492 35.939  1   93.52  ? 330 GLU D N   1 
ATOM   8195 C  CA  . GLU D 2 160 ? -60.614 -16.646 35.987  1   88.25  ? 330 GLU D CA  1 
ATOM   8196 C  C   . GLU D 2 160 ? -59.552 -17.319 36.861  1   84.39  ? 330 GLU D C   1 
ATOM   8197 O  O   . GLU D 2 160 ? -58.408 -17.445 36.397  1   85.01  ? 330 GLU D O   1 
ATOM   8198 C  CB  . GLU D 2 160 ? -61.012 -15.259 36.482  1   86.65  ? 330 GLU D CB  1 
ATOM   8199 C  CG  . GLU D 2 160 ? -61.931 -14.53  35.508  1   92.02  ? 330 GLU D CG  1 
ATOM   8200 C  CD  . GLU D 2 160 ? -62.321 -13.14  35.966  1   96.86  ? 330 GLU D CD  1 
ATOM   8201 O  OE1 . GLU D 2 160 ? -62.199 -12.87  37.177  1   99.67  ? 330 GLU D OE1 1 
ATOM   8202 O  OE2 . GLU D 2 160 ? -62.745 -12.332 35.117  1   100.28 ? 330 GLU D OE2 1 
ATOM   8203 N  N   . SER D 2 161 ? -59.923 -17.738 38.066  1   81.43  ? 331 SER D N   1 
ATOM   8204 C  CA  . SER D 2 161 ? -58.926 -18.327 38.993  1   83.08  ? 331 SER D CA  1 
ATOM   8205 C  C   . SER D 2 161 ? -58.361 -19.623 38.408  1   83.14  ? 331 SER D C   1 
ATOM   8206 O  O   . SER D 2 161 ? -57.179 -19.904 38.646  1   85.35  ? 331 SER D O   1 
ATOM   8207 C  CB  . SER D 2 161 ? -59.529 -18.567 40.337  1   88.68  ? 331 SER D CB  1 
ATOM   8208 O  OG  . SER D 2 161 ? -58.592 -19.173 41.215  1   94.84  ? 331 SER D OG  1 
ATOM   8209 N  N   . LEU D 2 162 ? -59.177 -20.38  37.679  1   81.99  ? 332 LEU D N   1 
ATOM   8210 C  CA  . LEU D 2 162 ? -58.725 -21.66  37.161  1   79.52  ? 332 LEU D CA  1 
ATOM   8211 C  C   . LEU D 2 162 ? -57.775 -21.44  35.982  1   76.5   ? 332 LEU D C   1 
ATOM   8212 O  O   . LEU D 2 162 ? -56.791 -22.162 35.822  1   74.7   ? 332 LEU D O   1 
ATOM   8213 C  CB  . LEU D 2 162 ? -59.918 -22.55  36.806  1   83     ? 332 LEU D CB  1 
ATOM   8214 C  CG  . LEU D 2 162 ? -59.587 -23.942 36.246  1   84.62  ? 332 LEU D CG  1 
ATOM   8215 C  CD1 . LEU D 2 162 ? -58.754 -24.747 37.239  1   88.94  ? 332 LEU D CD1 1 
ATOM   8216 C  CD2 . LEU D 2 162 ? -60.801 -24.762 35.828  1   87.42  ? 332 LEU D CD2 1 
ATOM   8217 N  N   . ALA D 2 163 ? -58.082 -20.436 35.157  1   74.91  ? 333 ALA D N   1 
ATOM   8218 C  CA  . ALA D 2 163 ? -57.222 -20.044 34.053  1   77.24  ? 333 ALA D CA  1 
ATOM   8219 C  C   . ALA D 2 163 ? -55.845 -19.573 34.548  1   78     ? 333 ALA D C   1 
ATOM   8220 O  O   . ALA D 2 163 ? -54.815 -19.931 33.96   1   82.8   ? 333 ALA D O   1 
ATOM   8221 C  CB  . ALA D 2 163 ? -57.933 -19.01  33.199  1   81.54  ? 333 ALA D CB  1 
ATOM   8222 N  N   . MET D 2 164 ? -55.814 -18.778 35.63   1   75.06  ? 334 MET D N   1 
ATOM   8223 C  CA  . MET D 2 164 ? -54.556 -18.297 36.192  1   75.94  ? 334 MET D CA  1 
ATOM   8224 C  C   . MET D 2 164 ? -53.703 -19.489 36.632  1   77.13  ? 334 MET D C   1 
ATOM   8225 O  O   . MET D 2 164 ? -52.479 -19.488 36.425  1   80.39  ? 334 MET D O   1 
ATOM   8226 C  CB  . MET D 2 164 ? -54.778 -17.386 37.409  1   75.99  ? 334 MET D CB  1 
ATOM   8227 C  CG  . MET D 2 164 ? -55.264 -15.982 37.102  1   81.56  ? 334 MET D CG  1 
ATOM   8228 S  SD  . MET D 2 164 ? -54.015 -14.926 36.34   1   92.87  ? 334 MET D SD  1 
ATOM   8229 C  CE  . MET D 2 164 ? -54.923 -13.374 36.296  1   97.8   ? 334 MET D CE  1 
ATOM   8230 N  N   . PHE D 2 165 ? -54.381 -20.475 37.253  1   75.29  ? 335 PHE D N   1 
ATOM   8231 C  CA  . PHE D 2 165 ? -53.791 -21.692 37.795  1   74.89  ? 335 PHE D CA  1 
ATOM   8232 C  C   . PHE D 2 165 ? -53.131 -22.524 36.699  1   73.59  ? 335 PHE D C   1 
ATOM   8233 O  O   . PHE D 2 165 ? -52.013 -23.01  36.879  1   70.8   ? 335 PHE D O   1 
ATOM   8234 C  CB  . PHE D 2 165 ? -54.862 -22.54  38.486  1   74.16  ? 335 PHE D CB  1 
ATOM   8235 C  CG  . PHE D 2 165 ? -54.46  -23.978 38.765  1   74.99  ? 335 PHE D CG  1 
ATOM   8236 C  CD1 . PHE D 2 165 ? -53.53  -24.279 39.755  1   75.45  ? 335 PHE D CD1 1 
ATOM   8237 C  CD2 . PHE D 2 165 ? -55.035 -25.025 38.044  1   78.08  ? 335 PHE D CD2 1 
ATOM   8238 C  CE1 . PHE D 2 165 ? -53.179 -25.599 40.01   1   81.61  ? 335 PHE D CE1 1 
ATOM   8239 C  CE2 . PHE D 2 165 ? -54.699 -26.348 38.313  1   78.58  ? 335 PHE D CE2 1 
ATOM   8240 C  CZ  . PHE D 2 165 ? -53.765 -26.636 39.286  1   81.98  ? 335 PHE D CZ  1 
ATOM   8241 N  N   . LEU D 2 166 ? -53.863 -22.712 35.592  1   75.2   ? 336 LEU D N   1 
ATOM   8242 C  CA  . LEU D 2 166 ? -53.381 -23.49  34.464  1   72.09  ? 336 LEU D CA  1 
ATOM   8243 C  C   . LEU D 2 166 ? -52.193 -22.755 33.858  1   70.43  ? 336 LEU D C   1 
ATOM   8244 O  O   . LEU D 2 166 ? -51.175 -23.376 33.548  1   73.94  ? 336 LEU D O   1 
ATOM   8245 C  CB  . LEU D 2 166 ? -54.497 -23.701 33.443  1   68.97  ? 336 LEU D CB  1 
ATOM   8246 C  CG  . LEU D 2 166 ? -55.679 -24.563 33.895  1   71.64  ? 336 LEU D CG  1 
ATOM   8247 C  CD1 . LEU D 2 166 ? -56.762 -24.547 32.835  1   75.4   ? 336 LEU D CD1 1 
ATOM   8248 C  CD2 . LEU D 2 166 ? -55.268 -25.991 34.19   1   70.09  ? 336 LEU D CD2 1 
ATOM   8249 N  N   . GLY D 2 167 ? -52.352 -21.429 33.702  1   66.46  ? 337 GLY D N   1 
ATOM   8250 C  CA  . GLY D 2 167 ? -51.305 -20.554 33.198  1   60.66  ? 337 GLY D CA  1 
ATOM   8251 C  C   . GLY D 2 167 ? -49.994 -20.734 33.961  1   61.23  ? 337 GLY D C   1 
ATOM   8252 O  O   . GLY D 2 167 ? -48.925 -20.843 33.363  1   59.79  ? 337 GLY D O   1 
ATOM   8253 N  N   . GLU D 2 168 ? -50.093 -20.783 35.292  1   63.72  ? 338 GLU D N   1 
ATOM   8254 C  CA  . GLU D 2 168 ? -48.936 -20.955 36.155  1   58.9   ? 338 GLU D CA  1 
ATOM   8255 C  C   . GLU D 2 168 ? -48.329 -22.355 36.061  1   63.48  ? 338 GLU D C   1 
ATOM   8256 O  O   . GLU D 2 168 ? -47.127 -22.478 36.29   1   65.97  ? 338 GLU D O   1 
ATOM   8257 C  CB  . GLU D 2 168 ? -49.301 -20.682 37.608  1   55.45  ? 338 GLU D CB  1 
ATOM   8258 C  CG  . GLU D 2 168 ? -48.892 -19.293 38.058  1   56.45  ? 338 GLU D CG  1 
ATOM   8259 C  CD  . GLU D 2 168 ? -49.281 -18.941 39.477  1   61.69  ? 338 GLU D CD  1 
ATOM   8260 O  OE1 . GLU D 2 168 ? -48.782 -19.589 40.435  1   64.04  ? 338 GLU D OE1 1 
ATOM   8261 O  OE2 . GLU D 2 168 ? -50.075 -17.984 39.598  1   63.28  ? 338 GLU D OE2 1 
ATOM   8262 N  N   . LEU D 2 169 ? -49.131 -23.4   35.784  1   61.97  ? 339 LEU D N   1 
ATOM   8263 C  CA  . LEU D 2 169 ? -48.596 -24.752 35.694  1   61.17  ? 339 LEU D CA  1 
ATOM   8264 C  C   . LEU D 2 169 ? -47.631 -24.848 34.519  1   60.68  ? 339 LEU D C   1 
ATOM   8265 O  O   . LEU D 2 169 ? -46.606 -25.503 34.642  1   65.4   ? 339 LEU D O   1 
ATOM   8266 C  CB  . LEU D 2 169 ? -49.681 -25.821 35.602  1   67.21  ? 339 LEU D CB  1 
ATOM   8267 C  CG  . LEU D 2 169 ? -50.483 -26.126 36.876  1   67.92  ? 339 LEU D CG  1 
ATOM   8268 C  CD1 . LEU D 2 169 ? -51.525 -27.19  36.572  1   73.1   ? 339 LEU D CD1 1 
ATOM   8269 C  CD2 . LEU D 2 169 ? -49.595 -26.598 38.014  1   64.56  ? 339 LEU D CD2 1 
ATOM   8270 N  N   . SER D 2 170 ? -47.942 -24.154 33.415  1   60.01  ? 340 SER D N   1 
ATOM   8271 C  CA  . SER D 2 170 ? -47.108 -24.11  32.215  1   62.56  ? 340 SER D CA  1 
ATOM   8272 C  C   . SER D 2 170 ? -45.702 -23.568 32.511  1   69.95  ? 340 SER D C   1 
ATOM   8273 O  O   . SER D 2 170 ? -44.737 -23.977 31.863  1   76.9   ? 340 SER D O   1 
ATOM   8274 C  CB  . SER D 2 170 ? -47.787 -23.336 31.08   1   63.61  ? 340 SER D CB  1 
ATOM   8275 O  OG  . SER D 2 170 ? -47.635 -21.925 31.198  1   71.17  ? 340 SER D OG  1 
ATOM   8276 N  N   . LEU D 2 171 ? -45.577 -22.645 33.487  1   71.8   ? 341 LEU D N   1 
ATOM   8277 C  CA  . LEU D 2 171 ? -44.304 -22.035 33.865  1   62.96  ? 341 LEU D CA  1 
ATOM   8278 C  C   . LEU D 2 171 ? -43.263 -23.092 34.235  1   59.82  ? 341 LEU D C   1 
ATOM   8279 O  O   . LEU D 2 171 ? -42.081 -22.892 33.994  1   60.66  ? 341 LEU D O   1 
ATOM   8280 C  CB  . LEU D 2 171 ? -44.5   -21.047 35.02   1   59.89  ? 341 LEU D CB  1 
ATOM   8281 C  CG  . LEU D 2 171 ? -45.358 -19.807 34.731  1   54.59  ? 341 LEU D CG  1 
ATOM   8282 C  CD1 . LEU D 2 171 ? -45.407 -18.896 35.93   1   50.88  ? 341 LEU D CD1 1 
ATOM   8283 C  CD2 . LEU D 2 171 ? -44.854 -19.014 33.529  1   55.75  ? 341 LEU D CD2 1 
ATOM   8284 N  N   . ILE D 2 172 ? -43.713 -24.214 34.81   1   62.71  ? 342 ILE D N   1 
ATOM   8285 C  CA  . ILE D 2 172 ? -42.854 -25.189 35.465  1   60.59  ? 342 ILE D CA  1 
ATOM   8286 C  C   . ILE D 2 172 ? -42.069 -26.041 34.455  1   61.9   ? 342 ILE D C   1 
ATOM   8287 O  O   . ILE D 2 172 ? -40.904 -26.392 34.701  1   57.64  ? 342 ILE D O   1 
ATOM   8288 C  CB  . ILE D 2 172 ? -43.708 -26.061 36.397  1   59.34  ? 342 ILE D CB  1 
ATOM   8289 C  CG1 . ILE D 2 172 ? -44.372 -25.229 37.516  1   56     ? 342 ILE D CG1 1 
ATOM   8290 C  CG2 . ILE D 2 172 ? -42.897 -27.257 36.914  1   60.56  ? 342 ILE D CG2 1 
ATOM   8291 C  CD1 . ILE D 2 172 ? -43.491 -24.934 38.717  1   55.65  ? 342 ILE D CD1 1 
ATOM   8292 N  N   . ASP D 2 173 ? -42.713 -26.368 33.323  1   60.29  ? 343 ASP D N   1 
ATOM   8293 C  CA  . ASP D 2 173 ? -42.243 -27.403 32.416  1   60.95  ? 343 ASP D CA  1 
ATOM   8294 C  C   . ASP D 2 173 ? -41.844 -26.789 31.078  1   63.08  ? 343 ASP D C   1 
ATOM   8295 O  O   . ASP D 2 173 ? -42.714 -26.534 30.246  1   69.25  ? 343 ASP D O   1 
ATOM   8296 C  CB  . ASP D 2 173 ? -43.341 -28.427 32.186  1   63.61  ? 343 ASP D CB  1 
ATOM   8297 C  CG  . ASP D 2 173 ? -43.84  -29.112 33.444  1   67.34  ? 343 ASP D CG  1 
ATOM   8298 O  OD1 . ASP D 2 173 ? -42.983 -29.624 34.194  1   68.34  ? 343 ASP D OD1 1 
ATOM   8299 O  OD2 . ASP D 2 173 ? -45.07  -29.121 33.658  1   68.74  ? 343 ASP D OD2 1 
ATOM   8300 N  N   . ALA D 2 174 ? -40.534 -26.572 30.88   1   63.96  ? 344 ALA D N   1 
ATOM   8301 C  CA  . ALA D 2 174 ? -39.981 -25.928 29.688  1   69.89  ? 344 ALA D CA  1 
ATOM   8302 C  C   . ALA D 2 174 ? -40.348 -26.713 28.424  1   73.91  ? 344 ALA D C   1 
ATOM   8303 O  O   . ALA D 2 174 ? -40.641 -26.127 27.373  1   71.78  ? 344 ALA D O   1 
ATOM   8304 C  CB  . ALA D 2 174 ? -38.476 -25.818 29.818  1   69.01  ? 344 ALA D CB  1 
ATOM   8305 N  N   . ASP D 2 175 ? -40.264 -28.045 28.551  1   68.03  ? 345 ASP D N   1 
ATOM   8306 C  CA  . ASP D 2 175 ? -40.83  -28.979 27.602  1   68.97  ? 345 ASP D CA  1 
ATOM   8307 C  C   . ASP D 2 175 ? -42.181 -29.402 28.162  1   69.35  ? 345 ASP D C   1 
ATOM   8308 O  O   . ASP D 2 175 ? -42.224 -30.093 29.176  1   67.67  ? 345 ASP D O   1 
ATOM   8309 C  CB  . ASP D 2 175 ? -39.931 -30.189 27.392  1   71.92  ? 345 ASP D CB  1 
ATOM   8310 C  CG  . ASP D 2 175 ? -40.55  -31.277 26.532  1   78.09  ? 345 ASP D CG  1 
ATOM   8311 O  OD1 . ASP D 2 175 ? -41.517 -30.976 25.807  1   82.99  ? 345 ASP D OD1 1 
ATOM   8312 O  OD2 . ASP D 2 175 ? -40.09  -32.42  26.624  1   79.01  ? 345 ASP D OD2 1 
ATOM   8313 N  N   . PRO D 2 176 ? -43.321 -29.067 27.505  1   70.19  ? 346 PRO D N   1 
ATOM   8314 C  CA  . PRO D 2 176 ? -43.334 -28.461 26.164  1   70.37  ? 346 PRO D CA  1 
ATOM   8315 C  C   . PRO D 2 176 ? -43.471 -26.949 25.962  1   70.31  ? 346 PRO D C   1 
ATOM   8316 O  O   . PRO D 2 176 ? -43.411 -26.494 24.824  1   80.57  ? 346 PRO D O   1 
ATOM   8317 C  CB  . PRO D 2 176 ? -44.566 -29.185 25.594  1   65.25  ? 346 PRO D CB  1 
ATOM   8318 C  CG  . PRO D 2 176 ? -45.523 -29.204 26.756  1   65.57  ? 346 PRO D CG  1 
ATOM   8319 C  CD  . PRO D 2 176 ? -44.672 -29.37  27.999  1   64.76  ? 346 PRO D CD  1 
ATOM   8320 N  N   . TYR D 2 177 ? -43.639 -26.178 27.041  1   64.38  ? 347 TYR D N   1 
ATOM   8321 C  CA  . TYR D 2 177 ? -44.301 -24.881 26.966  1   63.34  ? 347 TYR D CA  1 
ATOM   8322 C  C   . TYR D 2 177 ? -43.444 -23.762 26.362  1   64.1   ? 347 TYR D C   1 
ATOM   8323 O  O   . TYR D 2 177 ? -43.988 -22.725 25.982  1   68.02  ? 347 TYR D O   1 
ATOM   8324 C  CB  . TYR D 2 177 ? -44.972 -24.548 28.303  1   59.28  ? 347 TYR D CB  1 
ATOM   8325 C  CG  . TYR D 2 177 ? -46.131 -25.491 28.584  1   63.94  ? 347 TYR D CG  1 
ATOM   8326 C  CD1 . TYR D 2 177 ? -47.304 -25.427 27.838  1   66.46  ? 347 TYR D CD1 1 
ATOM   8327 C  CD2 . TYR D 2 177 ? -46.036 -26.477 29.558  1   67.56  ? 347 TYR D CD2 1 
ATOM   8328 C  CE1 . TYR D 2 177 ? -48.349 -26.307 28.069  1   70.07  ? 347 TYR D CE1 1 
ATOM   8329 C  CE2 . TYR D 2 177 ? -47.079 -27.36  29.802  1   70.16  ? 347 TYR D CE2 1 
ATOM   8330 C  CZ  . TYR D 2 177 ? -48.237 -27.282 29.048  1   71.05  ? 347 TYR D CZ  1 
ATOM   8331 O  OH  . TYR D 2 177 ? -49.265 -28.145 29.303  1   70.24  ? 347 TYR D OH  1 
ATOM   8332 N  N   . LEU D 2 178 ? -42.127 -23.953 26.235  1   62.01  ? 348 LEU D N   1 
ATOM   8333 C  CA  . LEU D 2 178 ? -41.294 -22.954 25.574  1   61.34  ? 348 LEU D CA  1 
ATOM   8334 C  C   . LEU D 2 178 ? -41.61  -22.842 24.073  1   66.5   ? 348 LEU D C   1 
ATOM   8335 O  O   . LEU D 2 178 ? -41.163 -21.896 23.425  1   62.82  ? 348 LEU D O   1 
ATOM   8336 C  CB  . LEU D 2 178 ? -39.816 -23.259 25.807  1   61.62  ? 348 LEU D CB  1 
ATOM   8337 C  CG  . LEU D 2 178 ? -39.253 -22.927 27.19   1   61.47  ? 348 LEU D CG  1 
ATOM   8338 C  CD1 . LEU D 2 178 ? -37.809 -23.373 27.252  1   61.76  ? 348 LEU D CD1 1 
ATOM   8339 C  CD2 . LEU D 2 178 ? -39.349 -21.45  27.493  1   57.51  ? 348 LEU D CD2 1 
ATOM   8340 N  N   . LYS D 2 179 ? -42.38  -23.788 23.514  1   70.64  ? 349 LYS D N   1 
ATOM   8341 C  CA  . LYS D 2 179 ? -42.783 -23.729 22.115  1   72.37  ? 349 LYS D CA  1 
ATOM   8342 C  C   . LYS D 2 179 ? -43.95  -22.761 21.914  1   76.06  ? 349 LYS D C   1 
ATOM   8343 O  O   . LYS D 2 179 ? -44.148 -22.273 20.804  1   86.52  ? 349 LYS D O   1 
ATOM   8344 C  CB  . LYS D 2 179 ? -43.294 -25.066 21.573  1   71.77  ? 349 LYS D CB  1 
ATOM   8345 C  CG  . LYS D 2 179 ? -42.357 -26.235 21.781  1   83.94  ? 349 LYS D CG  1 
ATOM   8346 C  CD  . LYS D 2 179 ? -43.081 -27.578 21.695  1   86.79  ? 349 LYS D CD  1 
ATOM   8347 C  CE  . LYS D 2 179 ? -42.163 -28.728 21.963  1   88.62  ? 349 LYS D CE  1 
ATOM   8348 N  NZ  . LYS D 2 179 ? -42.939 -29.969 22.004  1   89.48  ? 349 LYS D NZ  1 
ATOM   8349 N  N   . TYR D 2 180 ? -44.737 -22.509 22.968  1   68.54  ? 350 TYR D N   1 
ATOM   8350 C  CA  . TYR D 2 180 ? -45.912 -21.674 22.814  1   68.98  ? 350 TYR D CA  1 
ATOM   8351 C  C   . TYR D 2 180 ? -45.608 -20.244 23.256  1   68.7   ? 350 TYR D C   1 
ATOM   8352 O  O   . TYR D 2 180 ? -44.877 -20.026 24.218  1   71.95  ? 350 TYR D O   1 
ATOM   8353 C  CB  . TYR D 2 180 ? -47.065 -22.336 23.565  1   69.76  ? 350 TYR D CB  1 
ATOM   8354 C  CG  . TYR D 2 180 ? -47.308 -23.773 23.125  1   73.98  ? 350 TYR D CG  1 
ATOM   8355 C  CD1 . TYR D 2 180 ? -47.713 -24.067 21.828  1   72.14  ? 350 TYR D CD1 1 
ATOM   8356 C  CD2 . TYR D 2 180 ? -47.133 -24.827 24.013  1   73.73  ? 350 TYR D CD2 1 
ATOM   8357 C  CE1 . TYR D 2 180 ? -47.94  -25.373 21.435  1   75.51  ? 350 TYR D CE1 1 
ATOM   8358 C  CE2 . TYR D 2 180 ? -47.368 -26.135 23.63   1   71.95  ? 350 TYR D CE2 1 
ATOM   8359 C  CZ  . TYR D 2 180 ? -47.76  -26.406 22.338  1   75.43  ? 350 TYR D CZ  1 
ATOM   8360 O  OH  . TYR D 2 180 ? -47.967 -27.701 21.974  1   83.77  ? 350 TYR D OH  1 
ATOM   8361 N  N   . LEU D 2 181 ? -46.176 -19.278 22.527  1   67.57  ? 351 LEU D N   1 
ATOM   8362 C  CA  . LEU D 2 181 ? -46.136 -17.867 22.883  1   65.05  ? 351 LEU D CA  1 
ATOM   8363 C  C   . LEU D 2 181 ? -47.126 -17.629 24.02   1   64.18  ? 351 LEU D C   1 
ATOM   8364 O  O   . LEU D 2 181 ? -48.14  -18.306 24.109  1   67.6   ? 351 LEU D O   1 
ATOM   8365 C  CB  . LEU D 2 181 ? -46.486 -17.02  21.66   1   62.56  ? 351 LEU D CB  1 
ATOM   8366 C  CG  . LEU D 2 181 ? -45.358 -16.759 20.66   1   59.71  ? 351 LEU D CG  1 
ATOM   8367 C  CD1 . LEU D 2 181 ? -45.883 -16.055 19.415  1   57.94  ? 351 LEU D CD1 1 
ATOM   8368 C  CD2 . LEU D 2 181 ? -44.271 -15.924 21.33   1   60.85  ? 351 LEU D CD2 1 
ATOM   8369 N  N   . PRO D 2 182 ? -46.859 -16.677 24.934  1   61.24  ? 352 PRO D N   1 
ATOM   8370 C  CA  . PRO D 2 182 ? -47.769 -16.391 26.046  1   62.5   ? 352 PRO D CA  1 
ATOM   8371 C  C   . PRO D 2 182 ? -49.24  -16.245 25.679  1   66.1   ? 352 PRO D C   1 
ATOM   8372 O  O   . PRO D 2 182 ? -50.094 -16.801 26.363  1   70.85  ? 352 PRO D O   1 
ATOM   8373 C  CB  . PRO D 2 182 ? -47.201 -15.093 26.619  1   64.71  ? 352 PRO D CB  1 
ATOM   8374 C  CG  . PRO D 2 182 ? -45.716 -15.197 26.332  1   64.22  ? 352 PRO D CG  1 
ATOM   8375 C  CD  . PRO D 2 182 ? -45.648 -15.847 24.955  1   62.72  ? 352 PRO D CD  1 
ATOM   8376 N  N   . SER D 2 183 ? -49.52  -15.504 24.599  1   61.31  ? 353 SER D N   1 
ATOM   8377 C  CA  . SER D 2 183 ? -50.881 -15.312 24.126  1   57.79  ? 353 SER D CA  1 
ATOM   8378 C  C   . SER D 2 183 ? -51.569 -16.657 23.893  1   62.09  ? 353 SER D C   1 
ATOM   8379 O  O   . SER D 2 183 ? -52.759 -16.801 24.176  1   65.78  ? 353 SER D O   1 
ATOM   8380 C  CB  . SER D 2 183 ? -50.897 -14.489 22.881  1   58.49  ? 353 SER D CB  1 
ATOM   8381 O  OG  . SER D 2 183 ? -50.188 -15.189 21.878  1   68.47  ? 353 SER D OG  1 
ATOM   8382 N  N   . VAL D 2 184 ? -50.827 -17.632 23.349  1   62.86  ? 354 VAL D N   1 
ATOM   8383 C  CA  . VAL D 2 184 ? -51.362 -18.962 23.07   1   63.61  ? 354 VAL D CA  1 
ATOM   8384 C  C   . VAL D 2 184 ? -51.656 -19.719 24.371  1   61.16  ? 354 VAL D C   1 
ATOM   8385 O  O   . VAL D 2 184 ? -52.804 -20.088 24.621  1   59.03  ? 354 VAL D O   1 
ATOM   8386 C  CB  . VAL D 2 184 ? -50.457 -19.761 22.11   1   64.32  ? 354 VAL D CB  1 
ATOM   8387 C  CG1 . VAL D 2 184 ? -50.906 -21.203 21.939  1   61.28  ? 354 VAL D CG1 1 
ATOM   8388 C  CG2 . VAL D 2 184 ? -50.329 -19.077 20.753  1   64.82  ? 354 VAL D CG2 1 
ATOM   8389 N  N   . ILE D 2 185 ? -50.634 -19.929 25.214  1   57.34  ? 355 ILE D N   1 
ATOM   8390 C  CA  . ILE D 2 185 ? -50.861 -20.587 26.49   1   59.91  ? 355 ILE D CA  1 
ATOM   8391 C  C   . ILE D 2 185 ? -52.023 -19.922 27.223  1   66.81  ? 355 ILE D C   1 
ATOM   8392 O  O   . ILE D 2 185 ? -52.837 -20.623 27.822  1   71.22  ? 355 ILE D O   1 
ATOM   8393 C  CB  . ILE D 2 185 ? -49.608 -20.602 27.374  1   57     ? 355 ILE D CB  1 
ATOM   8394 C  CG1 . ILE D 2 185 ? -48.463 -21.332 26.692  1   57.26  ? 355 ILE D CG1 1 
ATOM   8395 C  CG2 . ILE D 2 185 ? -49.943 -21.205 28.741  1   56.88  ? 355 ILE D CG2 1 
ATOM   8396 C  CD1 . ILE D 2 185 ? -47.164 -21.316 27.48   1   54.14  ? 355 ILE D CD1 1 
ATOM   8397 N  N   . ALA D 2 186 ? -52.093 -18.58  27.173  1   64.87  ? 356 ALA D N   1 
ATOM   8398 C  CA  . ALA D 2 186 ? -53.177 -17.833 27.798  1   66.06  ? 356 ALA D CA  1 
ATOM   8399 C  C   . ALA D 2 186 ? -54.54  -18.207 27.214  1   71.12  ? 356 ALA D C   1 
ATOM   8400 O  O   . ALA D 2 186 ? -55.499 -18.345 27.968  1   69.41  ? 356 ALA D O   1 
ATOM   8401 C  CB  . ALA D 2 186 ? -52.936 -16.353 27.68   1   68.9   ? 356 ALA D CB  1 
ATOM   8402 N  N   . ALA D 2 187 ? -54.615 -18.35  25.877  1   71.91  ? 357 ALA D N   1 
ATOM   8403 C  CA  . ALA D 2 187 ? -55.834 -18.74  25.177  1   70.9   ? 357 ALA D CA  1 
ATOM   8404 C  C   . ALA D 2 187 ? -56.26  -20.149 25.58   1   71.19  ? 357 ALA D C   1 
ATOM   8405 O  O   . ALA D 2 187 ? -57.418 -20.338 25.919  1   72.18  ? 357 ALA D O   1 
ATOM   8406 C  CB  . ALA D 2 187 ? -55.678 -18.612 23.679  1   68.86  ? 357 ALA D CB  1 
ATOM   8407 N  N   . ALA D 2 188 ? -55.327 -21.113 25.554  1   72.99  ? 358 ALA D N   1 
ATOM   8408 C  CA  . ALA D 2 188 ? -55.593 -22.497 25.929  1   77.62  ? 358 ALA D CA  1 
ATOM   8409 C  C   . ALA D 2 188 ? -56.046 -22.579 27.382  1   76.61  ? 358 ALA D C   1 
ATOM   8410 O  O   . ALA D 2 188 ? -57.027 -23.241 27.698  1   79.92  ? 358 ALA D O   1 
ATOM   8411 C  CB  . ALA D 2 188 ? -54.367 -23.348 25.697  1   75.86  ? 358 ALA D CB  1 
ATOM   8412 N  N   . ALA D 2 189 ? -55.342 -21.867 28.258  1   77.37  ? 359 ALA D N   1 
ATOM   8413 C  CA  . ALA D 2 189 ? -55.673 -21.851 29.673  1   81.19  ? 359 ALA D CA  1 
ATOM   8414 C  C   . ALA D 2 189 ? -57.09  -21.323 29.909  1   85.03  ? 359 ALA D C   1 
ATOM   8415 O  O   . ALA D 2 189 ? -57.794 -21.827 30.782  1   89.88  ? 359 ALA D O   1 
ATOM   8416 C  CB  . ALA D 2 189 ? -54.644 -21.038 30.421  1   76.47  ? 359 ALA D CB  1 
ATOM   8417 N  N   . PHE D 2 190 ? -57.495 -20.306 29.134  1   82.86  ? 360 PHE D N   1 
ATOM   8418 C  CA  . PHE D 2 190 ? -58.792 -19.658 29.272  1   80.54  ? 360 PHE D CA  1 
ATOM   8419 C  C   . PHE D 2 190 ? -59.898 -20.602 28.796  1   86.62  ? 360 PHE D C   1 
ATOM   8420 O  O   . PHE D 2 190 ? -60.857 -20.859 29.526  1   90.86  ? 360 PHE D O   1 
ATOM   8421 C  CB  . PHE D 2 190 ? -58.836 -18.34  28.491  1   75.06  ? 360 PHE D CB  1 
ATOM   8422 C  CG  . PHE D 2 190 ? -60.151 -17.588 28.602  1   75.03  ? 360 PHE D CG  1 
ATOM   8423 C  CD1 . PHE D 2 190 ? -60.71  -17.331 29.852  1   77.14  ? 360 PHE D CD1 1 
ATOM   8424 C  CD2 . PHE D 2 190 ? -60.842 -17.183 27.46   1   78.11  ? 360 PHE D CD2 1 
ATOM   8425 C  CE1 . PHE D 2 190 ? -61.92  -16.661 29.953  1   82.21  ? 360 PHE D CE1 1 
ATOM   8426 C  CE2 . PHE D 2 190 ? -62.063 -16.532 27.563  1   79.57  ? 360 PHE D CE2 1 
ATOM   8427 C  CZ  . PHE D 2 190 ? -62.597 -16.266 28.809  1   83.11  ? 360 PHE D CZ  1 
ATOM   8428 N  N   . HIS D 2 191 ? -59.773 -21.098 27.561  1   84.97  ? 361 HIS D N   1 
ATOM   8429 C  CA  . HIS D 2 191 ? -60.701 -22.084 27.03   1   91.95  ? 361 HIS D CA  1 
ATOM   8430 C  C   . HIS D 2 191 ? -60.876 -23.256 28.002  1   93.44  ? 361 HIS D C   1 
ATOM   8431 O  O   . HIS D 2 191 ? -62.001 -23.61  28.345  1   97.24  ? 361 HIS D O   1 
ATOM   8432 C  CB  . HIS D 2 191 ? -60.254 -22.626 25.666  1   90.46  ? 361 HIS D CB  1 
ATOM   8433 C  CG  . HIS D 2 191 ? -61.124 -23.776 25.295  1   96.2   ? 361 HIS D CG  1 
ATOM   8434 N  ND1 . HIS D 2 191 ? -62.267 -23.659 24.535  1   97.97  ? 361 HIS D ND1 1 
ATOM   8435 C  CD2 . HIS D 2 191 ? -61.067 -25.054 25.692  1   96.61  ? 361 HIS D CD2 1 
ATOM   8436 C  CE1 . HIS D 2 191 ? -62.844 -24.844 24.432  1   102.11 ? 361 HIS D CE1 1 
ATOM   8437 N  NE2 . HIS D 2 191 ? -62.13  -25.704 25.128  1   101.38 ? 361 HIS D NE2 1 
ATOM   8438 N  N   . LEU D 2 192 ? -59.757 -23.873 28.406  1   86.26  ? 362 LEU D N   1 
ATOM   8439 C  CA  . LEU D 2 192 ? -59.746 -25.057 29.245  1   84.64  ? 362 LEU D CA  1 
ATOM   8440 C  C   . LEU D 2 192 ? -60.453 -24.817 30.579  1   84.86  ? 362 LEU D C   1 
ATOM   8441 O  O   . LEU D 2 192 ? -61.11  -25.717 31.098  1   86.78  ? 362 LEU D O   1 
ATOM   8442 C  CB  . LEU D 2 192 ? -58.289 -25.47  29.436  1   83.18  ? 362 LEU D CB  1 
ATOM   8443 C  CG  . LEU D 2 192 ? -58.058 -26.788 30.18   1   89.35  ? 362 LEU D CG  1 
ATOM   8444 C  CD1 . LEU D 2 192 ? -58.989 -27.875 29.64   1   91.59  ? 362 LEU D CD1 1 
ATOM   8445 C  CD2 . LEU D 2 192 ? -56.602 -27.243 30.119  1   88.07  ? 362 LEU D CD2 1 
ATOM   8446 N  N   . ALA D 2 193 ? -60.302 -23.611 31.136  1   84.28  ? 363 ALA D N   1 
ATOM   8447 C  CA  . ALA D 2 193 ? -60.852 -23.26  32.438  1   88.09  ? 363 ALA D CA  1 
ATOM   8448 C  C   . ALA D 2 193 ? -62.345 -22.951 32.32   1   95.46  ? 363 ALA D C   1 
ATOM   8449 O  O   . ALA D 2 193 ? -63.143 -23.326 33.185  1   99.44  ? 363 ALA D O   1 
ATOM   8450 C  CB  . ALA D 2 193 ? -60.091 -22.083 33.027  1   80.03  ? 363 ALA D CB  1 
ATOM   8451 N  N   . LEU D 2 194 ? -62.695 -22.235 31.244  1   96.79  ? 364 LEU D N   1 
ATOM   8452 C  CA  . LEU D 2 194 ? -64.052 -21.825 30.917  1   98.9   ? 364 LEU D CA  1 
ATOM   8453 C  C   . LEU D 2 194 ? -64.919 -23.063 30.667  1   103.62 ? 364 LEU D C   1 
ATOM   8454 O  O   . LEU D 2 194 ? -66.057 -23.132 31.136  1   108.29 ? 364 LEU D O   1 
ATOM   8455 C  CB  . LEU D 2 194 ? -63.914 -20.912 29.694  1   95.81  ? 364 LEU D CB  1 
ATOM   8456 C  CG  . LEU D 2 194 ? -65.153 -20.163 29.192  1   99.73  ? 364 LEU D CG  1 
ATOM   8457 C  CD1 . LEU D 2 194 ? -65.63  -19.081 30.149  1   101.62 ? 364 LEU D CD1 1 
ATOM   8458 C  CD2 . LEU D 2 194 ? -64.877 -19.576 27.816  1   97.14  ? 364 LEU D CD2 1 
ATOM   8459 N  N   . TYR D 2 195 ? -64.354 -24.054 29.957  1   102.23 ? 365 TYR D N   1 
ATOM   8460 C  CA  . TYR D 2 195 ? -65.003 -25.322 29.642  1   103.99 ? 365 TYR D CA  1 
ATOM   8461 C  C   . TYR D 2 195 ? -65.251 -26.137 30.911  1   104.29 ? 365 TYR D C   1 
ATOM   8462 O  O   . TYR D 2 195 ? -66.367 -26.588 31.146  1   109.11 ? 365 TYR D O   1 
ATOM   8463 C  CB  . TYR D 2 195 ? -64.142 -26.084 28.63   1   103.8  ? 365 TYR D CB  1 
ATOM   8464 C  CG  . TYR D 2 195 ? -64.752 -27.341 28.026  1   109.1  ? 365 TYR D CG  1 
ATOM   8465 C  CD1 . TYR D 2 195 ? -65.613 -27.268 26.932  1   111.21 ? 365 TYR D CD1 1 
ATOM   8466 C  CD2 . TYR D 2 195 ? -64.442 -28.599 28.53   1   110.71 ? 365 TYR D CD2 1 
ATOM   8467 C  CE1 . TYR D 2 195 ? -66.16  -28.407 26.358  1   115.45 ? 365 TYR D CE1 1 
ATOM   8468 C  CE2 . TYR D 2 195 ? -64.993 -29.742 27.973  1   113.75 ? 365 TYR D CE2 1 
ATOM   8469 C  CZ  . TYR D 2 195 ? -65.855 -29.647 26.892  1   116.69 ? 365 TYR D CZ  1 
ATOM   8470 O  OH  . TYR D 2 195 ? -66.39  -30.776 26.341  1   121.15 ? 365 TYR D OH  1 
ATOM   8471 N  N   . THR D 2 196 ? -64.206 -26.31  31.73   1   100.59 ? 366 THR D N   1 
ATOM   8472 C  CA  . THR D 2 196 ? -64.257 -27.088 32.964  1   101.09 ? 366 THR D CA  1 
ATOM   8473 C  C   . THR D 2 196 ? -65.36  -26.586 33.906  1   103.59 ? 366 THR D C   1 
ATOM   8474 O  O   . THR D 2 196 ? -66.097 -27.387 34.48   1   107.51 ? 366 THR D O   1 
ATOM   8475 C  CB  . THR D 2 196 ? -62.876 -27.115 33.625  1   98.41  ? 366 THR D CB  1 
ATOM   8476 O  OG1 . THR D 2 196 ? -61.978 -27.7   32.682  1   100.11 ? 366 THR D OG1 1 
ATOM   8477 C  CG2 . THR D 2 196 ? -62.842 -27.887 34.936  1   95.4   ? 366 THR D CG2 1 
ATOM   8478 N  N   . VAL D 2 197 ? -65.495 -25.26  34.046  1   102.02 ? 367 VAL D N   1 
ATOM   8479 C  CA  . VAL D 2 197 ? -66.381 -24.666 35.04   1   102.43 ? 367 VAL D CA  1 
ATOM   8480 C  C   . VAL D 2 197 ? -67.813 -24.569 34.514  1   103.55 ? 367 VAL D C   1 
ATOM   8481 O  O   . VAL D 2 197 ? -68.741 -24.941 35.223  1   104.42 ? 367 VAL D O   1 
ATOM   8482 C  CB  . VAL D 2 197 ? -65.855 -23.307 35.546  1   98.82  ? 367 VAL D CB  1 
ATOM   8483 C  CG1 . VAL D 2 197 ? -66.869 -22.571 36.417  1   99.33  ? 367 VAL D CG1 1 
ATOM   8484 C  CG2 . VAL D 2 197 ? -64.543 -23.466 36.301  1   97.51  ? 367 VAL D CG2 1 
ATOM   8485 N  N   . THR D 2 198 ? -67.979 -24.049 33.288  1   104.88 ? 368 THR D N   1 
ATOM   8486 C  CA  . THR D 2 198 ? -69.278 -23.664 32.746  1   111.92 ? 368 THR D CA  1 
ATOM   8487 C  C   . THR D 2 198 ? -69.758 -24.628 31.661  1   117.63 ? 368 THR D C   1 
ATOM   8488 O  O   . THR D 2 198 ? -70.962 -24.771 31.469  1   125.4  ? 368 THR D O   1 
ATOM   8489 C  CB  . THR D 2 198 ? -69.267 -22.228 32.205  1   112.45 ? 368 THR D CB  1 
ATOM   8490 O  OG1 . THR D 2 198 ? -68.529 -22.157 30.987  1   112.1  ? 368 THR D OG1 1 
ATOM   8491 C  CG2 . THR D 2 198 ? -68.722 -21.214 33.191  1   107.11 ? 368 THR D CG2 1 
ATOM   8492 N  N   . GLY D 2 199 ? -68.825 -25.237 30.914  1   119.33 ? 369 GLY D N   1 
ATOM   8493 C  CA  . GLY D 2 199 ? -69.161 -26.065 29.76   1   120.91 ? 369 GLY D CA  1 
ATOM   8494 C  C   . GLY D 2 199 ? -68.961 -25.342 28.421  1   119.97 ? 369 GLY D C   1 
ATOM   8495 O  O   . GLY D 2 199 ? -69.016 -25.968 27.365  1   115.92 ? 369 GLY D O   1 
ATOM   8496 N  N   . GLN D 2 200 ? -68.708 -24.027 28.462  1   121.49 ? 370 GLN D N   1 
ATOM   8497 C  CA  . GLN D 2 200 ? -68.646 -23.201 27.26   1   122.23 ? 370 GLN D CA  1 
ATOM   8498 C  C   . GLN D 2 200 ? -67.247 -23.216 26.64   1   113.63 ? 370 GLN D C   1 
ATOM   8499 O  O   . GLN D 2 200 ? -66.306 -23.77  27.203  1   105.47 ? 370 GLN D O   1 
ATOM   8500 C  CB  . GLN D 2 200 ? -68.94  -21.75  27.626  1   129.41 ? 370 GLN D CB  1 
ATOM   8501 C  CG  . GLN D 2 200 ? -70.286 -21.548 28.304  1   137.86 ? 370 GLN D CG  1 
ATOM   8502 C  CD  . GLN D 2 200 ? -70.308 -20.284 29.127  1   141.18 ? 370 GLN D CD  1 
ATOM   8503 O  OE1 . GLN D 2 200 ? -69.77  -19.247 28.732  1   139.8  ? 370 GLN D OE1 1 
ATOM   8504 N  NE2 . GLN D 2 200 ? -70.895 -20.372 30.309  1   147.63 ? 370 GLN D NE2 1 
ATOM   8505 N  N   . SER D 2 201 ? -67.119 -22.546 25.485  1   110.93 ? 371 SER D N   1 
ATOM   8506 C  CA  . SER D 2 201 ? -65.916 -22.591 24.67   1   108.9  ? 371 SER D CA  1 
ATOM   8507 C  C   . SER D 2 201 ? -65.277 -21.209 24.514  1   107.84 ? 371 SER D C   1 
ATOM   8508 O  O   . SER D 2 201 ? -65.769 -20.207 25.021  1   111.51 ? 371 SER D O   1 
ATOM   8509 C  CB  . SER D 2 201 ? -66.208 -23.207 23.327  1   111.21 ? 371 SER D CB  1 
ATOM   8510 O  OG  . SER D 2 201 ? -66.337 -24.615 23.439  1   114.75 ? 371 SER D OG  1 
ATOM   8511 N  N   . TRP D 2 202 ? -64.132 -21.203 23.832  1   106.9  ? 372 TRP D N   1 
ATOM   8512 C  CA  . TRP D 2 202 ? -63.428 -20.023 23.365  1   106.12 ? 372 TRP D CA  1 
ATOM   8513 C  C   . TRP D 2 202 ? -64.381 -19.162 22.534  1   106.15 ? 372 TRP D C   1 
ATOM   8514 O  O   . TRP D 2 202 ? -64.765 -19.541 21.427  1   113.14 ? 372 TRP D O   1 
ATOM   8515 C  CB  . TRP D 2 202 ? -62.212 -20.523 22.565  1   105.96 ? 372 TRP D CB  1 
ATOM   8516 C  CG  . TRP D 2 202 ? -61.318 -19.494 21.929  1   102.47 ? 372 TRP D CG  1 
ATOM   8517 C  CD1 . TRP D 2 202 ? -61.194 -19.244 20.593  1   101.29 ? 372 TRP D CD1 1 
ATOM   8518 C  CD2 . TRP D 2 202 ? -60.391 -18.61  22.6    1   99.5   ? 372 TRP D CD2 1 
ATOM   8519 N  NE1 . TRP D 2 202 ? -60.265 -18.259 20.381  1   103.87 ? 372 TRP D NE1 1 
ATOM   8520 C  CE2 . TRP D 2 202 ? -59.756 -17.85  21.588  1   98.36  ? 372 TRP D CE2 1 
ATOM   8521 C  CE3 . TRP D 2 202 ? -60.05  -18.381 23.941  1   93.47  ? 372 TRP D CE3 1 
ATOM   8522 C  CZ2 . TRP D 2 202 ? -58.8   -16.883 21.882  1   87.39  ? 372 TRP D CZ2 1 
ATOM   8523 C  CZ3 . TRP D 2 202 ? -59.107 -17.423 24.232  1   85.55  ? 372 TRP D CZ3 1 
ATOM   8524 C  CH2 . TRP D 2 202 ? -58.502 -16.69  23.212  1   86.35  ? 372 TRP D CH2 1 
ATOM   8525 N  N   . PRO D 2 203 ? -64.809 -17.981 23.044  1   102.48 ? 373 PRO D N   1 
ATOM   8526 C  CA  . PRO D 2 203 ? -65.859 -17.197 22.39   1   102.58 ? 373 PRO D CA  1 
ATOM   8527 C  C   . PRO D 2 203 ? -65.466 -16.586 21.049  1   97.28  ? 373 PRO D C   1 
ATOM   8528 O  O   . PRO D 2 203 ? -64.295 -16.379 20.766  1   90.51  ? 373 PRO D O   1 
ATOM   8529 C  CB  . PRO D 2 203 ? -66.207 -16.129 23.439  1   104.09 ? 373 PRO D CB  1 
ATOM   8530 C  CG  . PRO D 2 203 ? -64.935 -15.972 24.245  1   100.61 ? 373 PRO D CG  1 
ATOM   8531 C  CD  . PRO D 2 203 ? -64.309 -17.35  24.278  1   99.67  ? 373 PRO D CD  1 
ATOM   8532 N  N   . GLU D 2 204 ? -66.48  -16.268 20.244  1   104.43 ? 374 GLU D N   1 
ATOM   8533 C  CA  . GLU D 2 204 ? -66.28  -15.776 18.89   1   107.9  ? 374 GLU D CA  1 
ATOM   8534 C  C   . GLU D 2 204 ? -65.552 -14.429 18.905  1   101.93 ? 374 GLU D C   1 
ATOM   8535 O  O   . GLU D 2 204 ? -64.742 -14.147 18.023  1   98.16  ? 374 GLU D O   1 
ATOM   8536 C  CB  . GLU D 2 204 ? -67.638 -15.755 18.18   1   108.96 ? 374 GLU D CB  1 
ATOM   8537 C  CG  . GLU D 2 204 ? -67.617 -15.115 16.793  1   112.3  ? 374 GLU D CG  1 
ATOM   8538 C  CD  . GLU D 2 204 ? -66.685 -15.71  15.747  1   111.5  ? 374 GLU D CD  1 
ATOM   8539 O  OE1 . GLU D 2 204 ? -66.288 -16.891 15.841  1   106.86 ? 374 GLU D OE1 1 
ATOM   8540 O  OE2 . GLU D 2 204 ? -66.33  -14.954 14.825  1   113.34 ? 374 GLU D OE2 1 
ATOM   8541 N  N   . SER D 2 205 ? -65.877 -13.601 19.909  1   99.08  ? 375 SER D N   1 
ATOM   8542 C  CA  . SER D 2 205 ? -65.336 -12.262 20.09   1   94.63  ? 375 SER D CA  1 
ATOM   8543 C  C   . SER D 2 205 ? -63.811 -12.29  20.212  1   90.27  ? 375 SER D C   1 
ATOM   8544 O  O   . SER D 2 205 ? -63.127 -11.464 19.612  1   87.77  ? 375 SER D O   1 
ATOM   8545 C  CB  . SER D 2 205 ? -65.971 -11.591 21.279  1   94.2   ? 375 SER D CB  1 
ATOM   8546 O  OG  . SER D 2 205 ? -65.963 -12.463 22.402  1   94.06  ? 375 SER D OG  1 
ATOM   8547 N  N   . LEU D 2 206 ? -63.295 -13.262 20.973  1   86.4   ? 376 LEU D N   1 
ATOM   8548 C  CA  . LEU D 2 206 ? -61.864 -13.455 21.14   1   84.13  ? 376 LEU D CA  1 
ATOM   8549 C  C   . LEU D 2 206 ? -61.229 -14.03  19.87   1   87.87  ? 376 LEU D C   1 
ATOM   8550 O  O   . LEU D 2 206 ? -60.104 -13.653 19.554  1   90.75  ? 376 LEU D O   1 
ATOM   8551 C  CB  . LEU D 2 206 ? -61.56  -14.308 22.37   1   80.41  ? 376 LEU D CB  1 
ATOM   8552 C  CG  . LEU D 2 206 ? -61.745 -13.608 23.723  1   76.73  ? 376 LEU D CG  1 
ATOM   8553 C  CD1 . LEU D 2 206 ? -61.526 -14.57  24.877  1   73.63  ? 376 LEU D CD1 1 
ATOM   8554 C  CD2 . LEU D 2 206 ? -60.863 -12.377 23.861  1   72.95  ? 376 LEU D CD2 1 
ATOM   8555 N  N   . VAL D 2 207 ? -61.938 -14.916 19.147  1   83.61  ? 377 VAL D N   1 
ATOM   8556 C  CA  . VAL D 2 207 ? -61.473 -15.381 17.849  1   83.55  ? 377 VAL D CA  1 
ATOM   8557 C  C   . VAL D 2 207 ? -61.195 -14.155 16.978  1   86.49  ? 377 VAL D C   1 
ATOM   8558 O  O   . VAL D 2 207 ? -60.159 -14.071 16.325  1   87.95  ? 377 VAL D O   1 
ATOM   8559 C  CB  . VAL D 2 207 ? -62.435 -16.377 17.152  1   88.53  ? 377 VAL D CB  1 
ATOM   8560 C  CG1 . VAL D 2 207 ? -61.989 -16.754 15.742  1   83.46  ? 377 VAL D CG1 1 
ATOM   8561 C  CG2 . VAL D 2 207 ? -62.657 -17.649 17.965  1   88.15  ? 377 VAL D CG2 1 
ATOM   8562 N  N   . GLN D 2 208 ? -62.126 -13.195 16.983  1   91.09  ? 378 GLN D N   1 
ATOM   8563 C  CA  . GLN D 2 208 ? -61.988 -11.971 16.208  1   95.48  ? 378 GLN D CA  1 
ATOM   8564 C  C   . GLN D 2 208 ? -60.784 -11.153 16.687  1   93.92  ? 378 GLN D C   1 
ATOM   8565 O  O   . GLN D 2 208 ? -59.999 -10.675 15.874  1   94.26  ? 378 GLN D O   1 
ATOM   8566 C  CB  . GLN D 2 208 ? -63.304 -11.193 16.234  1   102.72 ? 378 GLN D CB  1 
ATOM   8567 C  CG  . GLN D 2 208 ? -64.306 -11.666 15.186  1   108.56 ? 378 GLN D CG  1 
ATOM   8568 C  CD  . GLN D 2 208 ? -63.675 -11.672 13.813  1   114.25 ? 378 GLN D CD  1 
ATOM   8569 O  OE1 . GLN D 2 208 ? -63.59  -12.71  13.151  1   111.18 ? 378 GLN D OE1 1 
ATOM   8570 N  NE2 . GLN D 2 208 ? -63.162 -10.519 13.4    1   117.56 ? 378 GLN D NE2 1 
ATOM   8571 N  N   . LYS D 2 209 ? -60.634 -11     18.01   1   88.7   ? 379 LYS D N   1 
ATOM   8572 C  CA  . LYS D 2 209 ? -59.574 -10.203 18.609  1   87.4   ? 379 LYS D CA  1 
ATOM   8573 C  C   . LYS D 2 209 ? -58.188 -10.781 18.316  1   86.55  ? 379 LYS D C   1 
ATOM   8574 O  O   . LYS D 2 209 ? -57.329 -10.049 17.83   1   82.41  ? 379 LYS D O   1 
ATOM   8575 C  CB  . LYS D 2 209 ? -59.763 -10.128 20.128  1   90.77  ? 379 LYS D CB  1 
ATOM   8576 C  CG  . LYS D 2 209 ? -58.814 -9.163  20.851  1   87.91  ? 379 LYS D CG  1 
ATOM   8577 C  CD  . LYS D 2 209 ? -58.913 -9.212  22.375  1   88.82  ? 379 LYS D CD  1 
ATOM   8578 C  CE  . LYS D 2 209 ? -57.967 -8.293  23.072  1   83.06  ? 379 LYS D CE  1 
ATOM   8579 N  NZ  . LYS D 2 209 ? -58.272 -6.885  22.818  1   84.47  ? 379 LYS D NZ  1 
ATOM   8580 N  N   . THR D 2 210 ? -57.984 -12.078 18.63   1   85.93  ? 380 THR D N   1 
ATOM   8581 C  CA  . THR D 2 210 ? -56.687 -12.762 18.663  1   84.49  ? 380 THR D CA  1 
ATOM   8582 C  C   . THR D 2 210 ? -56.286 -13.38  17.32   1   84.22  ? 380 THR D C   1 
ATOM   8583 O  O   . THR D 2 210 ? -55.096 -13.552 17.048  1   80.1   ? 380 THR D O   1 
ATOM   8584 C  CB  . THR D 2 210 ? -56.683 -13.876 19.713  1   89.05  ? 380 THR D CB  1 
ATOM   8585 O  OG1 . THR D 2 210 ? -57.546 -14.932 19.283  1   91.32  ? 380 THR D OG1 1 
ATOM   8586 C  CG2 . THR D 2 210 ? -57.054 -13.38  21.1    1   89.02  ? 380 THR D CG2 1 
ATOM   8587 N  N   . GLY D 2 211 ? -57.28  -13.799 16.527  1   86.95  ? 381 GLY D N   1 
ATOM   8588 C  CA  . GLY D 2 211 ? -57.026 -14.542 15.306  1   81.63  ? 381 GLY D CA  1 
ATOM   8589 C  C   . GLY D 2 211 ? -56.767 -16.02  15.589  1   83.33  ? 381 GLY D C   1 
ATOM   8590 O  O   . GLY D 2 211 ? -56.348 -16.718 14.684  1   85.96  ? 381 GLY D O   1 
ATOM   8591 N  N   . TYR D 2 212 ? -57.04  -16.492 16.82   1   86.2   ? 382 TYR D N   1 
ATOM   8592 C  CA  . TYR D 2 212 ? -56.833 -17.881 17.217  1   88.46  ? 382 TYR D CA  1 
ATOM   8593 C  C   . TYR D 2 212 ? -58.172 -18.62  17.268  1   91.67  ? 382 TYR D C   1 
ATOM   8594 O  O   . TYR D 2 212 ? -59.093 -18.19  17.971  1   93.87  ? 382 TYR D O   1 
ATOM   8595 C  CB  . TYR D 2 212 ? -56.171 -18.042 18.592  1   82.25  ? 382 TYR D CB  1 
ATOM   8596 C  CG  . TYR D 2 212 ? -54.814 -17.385 18.779  1   79.44  ? 382 TYR D CG  1 
ATOM   8597 C  CD1 . TYR D 2 212 ? -53.909 -17.27  17.728  1   79.87  ? 382 TYR D CD1 1 
ATOM   8598 C  CD2 . TYR D 2 212 ? -54.442 -16.881 20.022  1   76.97  ? 382 TYR D CD2 1 
ATOM   8599 C  CE1 . TYR D 2 212 ? -52.678 -16.655 17.913  1   76.97  ? 382 TYR D CE1 1 
ATOM   8600 C  CE2 . TYR D 2 212 ? -53.217 -16.262 20.222  1   74.34  ? 382 TYR D CE2 1 
ATOM   8601 C  CZ  . TYR D 2 212 ? -52.337 -16.148 19.157  1   75.2   ? 382 TYR D CZ  1 
ATOM   8602 O  OH  . TYR D 2 212 ? -51.143 -15.534 19.364  1   70.21  ? 382 TYR D OH  1 
ATOM   8603 N  N   . THR D 2 213 ? -58.172 -19.797 16.637  1   88.46  ? 383 THR D N   1 
ATOM   8604 C  CA  . THR D 2 213 ? -59.344 -20.677 16.671  1   93.57  ? 383 THR D CA  1 
ATOM   8605 C  C   . THR D 2 213 ? -58.967 -21.848 17.531  1   96.55  ? 383 THR D C   1 
ATOM   8606 O  O   . THR D 2 213 ? -57.764 -22.127 17.646  1   96.58  ? 383 THR D O   1 
ATOM   8607 C  CB  . THR D 2 213 ? -59.637 -21.139 15.251  1   94.7   ? 383 THR D CB  1 
ATOM   8608 O  OG1 . THR D 2 213 ? -58.745 -22.228 15.046  1   94.17  ? 383 THR D OG1 1 
ATOM   8609 C  CG2 . THR D 2 213 ? -59.374 -20.059 14.219  1   92.94  ? 383 THR D CG2 1 
ATOM   8610 N  N   . LEU D 2 214 ? -59.954 -22.55  18.076  1   101.49 ? 384 LEU D N   1 
ATOM   8611 C  CA  . LEU D 2 214 ? -59.685 -23.73  18.933  1   101.61 ? 384 LEU D CA  1 
ATOM   8612 C  C   . LEU D 2 214 ? -58.852 -24.752 18.15   1   100.35 ? 384 LEU D C   1 
ATOM   8613 O  O   . LEU D 2 214 ? -58.217 -25.607 18.787  1   98.45  ? 384 LEU D O   1 
ATOM   8614 C  CB  . LEU D 2 214 ? -61.029 -24.288 19.382  1   99.26  ? 384 LEU D CB  1 
ATOM   8615 C  CG  . LEU D 2 214 ? -61.644 -23.586 20.593  1   97.02  ? 384 LEU D CG  1 
ATOM   8616 C  CD1 . LEU D 2 214 ? -62.907 -24.294 21.04   1   98.32  ? 384 LEU D CD1 1 
ATOM   8617 C  CD2 . LEU D 2 214 ? -60.599 -23.59  21.688  1   101.13 ? 384 LEU D CD2 1 
ATOM   8618 N  N   . GLU D 2 215 ? -58.862 -24.665 16.823  1   100.08 ? 385 GLU D N   1 
ATOM   8619 C  CA  . GLU D 2 215 ? -58.018 -25.558 15.999  1   101.52 ? 385 GLU D CA  1 
ATOM   8620 C  C   . GLU D 2 215 ? -56.562 -25.133 16.174  1   96.68  ? 385 GLU D C   1 
ATOM   8621 O  O   . GLU D 2 215 ? -55.73  -25.992 16.506  1   97.32  ? 385 GLU D O   1 
ATOM   8622 C  CB  . GLU D 2 215 ? -58.421 -25.432 14.533  1   103.64 ? 385 GLU D CB  1 
ATOM   8623 C  CG  . GLU D 2 215 ? -58.182 -26.702 13.725  1   110.09 ? 385 GLU D CG  1 
ATOM   8624 C  CD  . GLU D 2 215 ? -57.853 -26.415 12.272  1   121.71 ? 385 GLU D CD  1 
ATOM   8625 O  OE1 . GLU D 2 215 ? -57.884 -27.361 11.459  1   131.15 ? 385 GLU D OE1 1 
ATOM   8626 O  OE2 . GLU D 2 215 ? -57.567 -25.242 11.954  1   123.89 ? 385 GLU D OE2 1 
ATOM   8627 N  N   . THR D 2 216 ? -56.281 -23.848 15.966  1   96     ? 386 THR D N   1 
ATOM   8628 C  CA  . THR D 2 216 ? -54.906 -23.335 16.117  1   98.93  ? 386 THR D CA  1 
ATOM   8629 C  C   . THR D 2 216 ? -54.454 -23.535 17.544  1   92.76  ? 386 THR D C   1 
ATOM   8630 O  O   . THR D 2 216 ? -53.24  -23.675 17.76   1   87.58  ? 386 THR D O   1 
ATOM   8631 C  CB  . THR D 2 216 ? -54.892 -21.862 15.722  1   102.78 ? 386 THR D CB  1 
ATOM   8632 O  OG1 . THR D 2 216 ? -55.637 -21.195 16.735  1   108.78 ? 386 THR D OG1 1 
ATOM   8633 C  CG2 . THR D 2 216 ? -55.54  -21.621 14.372  1   100.42 ? 386 THR D CG2 1 
ATOM   8634 N  N   . LEU D 2 217 ? -55.392 -23.56  18.486  1   88.65  ? 387 LEU D N   1 
ATOM   8635 C  CA  . LEU D 2 217 ? -55.041 -23.671 19.919  1   81.78  ? 387 LEU D CA  1 
ATOM   8636 C  C   . LEU D 2 217 ? -55.075 -25.132 20.36   1   83.53  ? 387 LEU D C   1 
ATOM   8637 O  O   . LEU D 2 217 ? -54.856 -25.389 21.554  1   83.26  ? 387 LEU D O   1 
ATOM   8638 C  CB  . LEU D 2 217 ? -56.072 -22.847 20.68   1   80.06  ? 387 LEU D CB  1 
ATOM   8639 C  CG  . LEU D 2 217 ? -56.112 -21.353 20.356  1   79.35  ? 387 LEU D CG  1 
ATOM   8640 C  CD1 . LEU D 2 217 ? -57.278 -20.709 21.081  1   79.08  ? 387 LEU D CD1 1 
ATOM   8641 C  CD2 . LEU D 2 217 ? -54.796 -20.715 20.756  1   76.75  ? 387 LEU D CD2 1 
ATOM   8642 N  N   . LYS D 2 218 ? -55.344 -26.048 19.437  1   86.51  ? 388 LYS D N   1 
ATOM   8643 C  CA  . LYS D 2 218 ? -55.493 -27.474 19.829  1   94.61  ? 388 LYS D CA  1 
ATOM   8644 C  C   . LYS D 2 218 ? -54.162 -28.033 20.349  1   95.81  ? 388 LYS D C   1 
ATOM   8645 O  O   . LYS D 2 218 ? -54.176 -28.593 21.459  1   101.6  ? 388 LYS D O   1 
ATOM   8646 C  CB  . LYS D 2 218 ? -56.042 -28.333 18.684  1   103.23 ? 388 LYS D CB  1 
ATOM   8647 C  CG  . LYS D 2 218 ? -56.462 -29.737 19.083  1   110.16 ? 388 LYS D CG  1 
ATOM   8648 C  CD  . LYS D 2 218 ? -56.451 -30.71  17.913  1   118.69 ? 388 LYS D CD  1 
ATOM   8649 C  CE  . LYS D 2 218 ? -56.904 -32.077 18.315  1   123.9  ? 388 LYS D CE  1 
ATOM   8650 N  NZ  . LYS D 2 218 ? -58.125 -32.477 17.612  1   128.09 ? 388 LYS D NZ  1 
ATOM   8651 N  N   . PRO D 2 219 ? -53.026 -27.945 19.624  1   91.76  ? 389 PRO D N   1 
ATOM   8652 C  CA  . PRO D 2 219 ? -51.797 -28.525 20.134  1   87.74  ? 389 PRO D CA  1 
ATOM   8653 C  C   . PRO D 2 219 ? -51.572 -28.117 21.578  1   86.89  ? 389 PRO D C   1 
ATOM   8654 O  O   . PRO D 2 219 ? -51.413 -28.996 22.442  1   87.96  ? 389 PRO D O   1 
ATOM   8655 C  CB  . PRO D 2 219 ? -50.768 -27.928 19.192  1   84.4   ? 389 PRO D CB  1 
ATOM   8656 C  CG  . PRO D 2 219 ? -51.5   -27.81  17.884  1   83.31  ? 389 PRO D CG  1 
ATOM   8657 C  CD  . PRO D 2 219 ? -52.863 -27.322 18.316  1   86.36  ? 389 PRO D CD  1 
ATOM   8658 N  N   . CYS D 2 220 ? -51.556 -26.809 21.84   1   81.6   ? 390 CYS D N   1 
ATOM   8659 C  CA  . CYS D 2 220 ? -51.305 -26.306 23.215  1   82.94  ? 390 CYS D CA  1 
ATOM   8660 C  C   . CYS D 2 220 ? -52.332 -26.916 24.177  1   83.15  ? 390 CYS D C   1 
ATOM   8661 O  O   . CYS D 2 220 ? -51.923 -27.448 25.221  1   80.95  ? 390 CYS D O   1 
ATOM   8662 C  CB  . CYS D 2 220 ? -51.356 -24.783 23.261  1   80.7   ? 390 CYS D CB  1 
ATOM   8663 S  SG  . CYS D 2 220 ? -50.788 -24.073 24.826  1   74.71  ? 390 CYS D SG  1 
ATOM   8664 N  N   . LEU D 2 221 ? -53.611 -26.84  23.822  1   85.14  ? 391 LEU D N   1 
ATOM   8665 C  CA  . LEU D 2 221 ? -54.67  -27.404 24.692  1   87.06  ? 391 LEU D CA  1 
ATOM   8666 C  C   . LEU D 2 221 ? -54.365 -28.888 24.959  1   86.29  ? 391 LEU D C   1 
ATOM   8667 O  O   . LEU D 2 221 ? -54.571 -29.321 26.1    1   88.38  ? 391 LEU D O   1 
ATOM   8668 C  CB  . LEU D 2 221 ? -56.046 -27.201 24.064  1   93.49  ? 391 LEU D CB  1 
ATOM   8669 C  CG  . LEU D 2 221 ? -56.814 -25.962 24.529  1   98.42  ? 391 LEU D CG  1 
ATOM   8670 C  CD1 . LEU D 2 221 ? -57.749 -25.464 23.445  1   99.09  ? 391 LEU D CD1 1 
ATOM   8671 C  CD2 . LEU D 2 221 ? -57.576 -26.26  25.804  1   103.1  ? 391 LEU D CD2 1 
ATOM   8672 N  N   . LEU D 2 222 ? -53.88  -29.626 23.961  1   81.64  ? 392 LEU D N   1 
ATOM   8673 C  CA  . LEU D 2 222 ? -53.589 -31.031 24.229  1   88.53  ? 392 LEU D CA  1 
ATOM   8674 C  C   . LEU D 2 222 ? -52.556 -31.166 25.345  1   88.65  ? 392 LEU D C   1 
ATOM   8675 O  O   . LEU D 2 222 ? -52.789 -31.851 26.337  1   91.8   ? 392 LEU D O   1 
ATOM   8676 C  CB  . LEU D 2 222 ? -53.157 -31.782 22.967  1   85.63  ? 392 LEU D CB  1 
ATOM   8677 C  CG  . LEU D 2 222 ? -54.271 -32.067 21.953  1   86.08  ? 392 LEU D CG  1 
ATOM   8678 C  CD1 . LEU D 2 222 ? -53.707 -32.783 20.737  1   85.76  ? 392 LEU D CD1 1 
ATOM   8679 C  CD2 . LEU D 2 222 ? -55.478 -32.8   22.557  1   84.34  ? 392 LEU D CD2 1 
ATOM   8680 N  N   . ASP D 2 223 ? -51.411 -30.505 25.166  1   89.68  ? 393 ASP D N   1 
ATOM   8681 C  CA  . ASP D 2 223 ? -50.359 -30.449 26.167  1   87.52  ? 393 ASP D CA  1 
ATOM   8682 C  C   . ASP D 2 223 ? -50.906 -29.98  27.514  1   85.9   ? 393 ASP D C   1 
ATOM   8683 O  O   . ASP D 2 223 ? -50.54  -30.556 28.538  1   92.76  ? 393 ASP D O   1 
ATOM   8684 C  CB  . ASP D 2 223 ? -49.218 -29.543 25.737  1   87.67  ? 393 ASP D CB  1 
ATOM   8685 C  CG  . ASP D 2 223 ? -48.252 -30.142 24.727  1   88.98  ? 393 ASP D CG  1 
ATOM   8686 O  OD1 . ASP D 2 223 ? -47.913 -31.339 24.889  1   93.94  ? 393 ASP D OD1 1 
ATOM   8687 O  OD2 . ASP D 2 223 ? -47.823 -29.396 23.814  1   84.29  ? 393 ASP D OD2 1 
ATOM   8688 N  N   . LEU D 2 224 ? -51.755 -28.94  27.509  1   74.68  ? 394 LEU D N   1 
ATOM   8689 C  CA  . LEU D 2 224 ? -52.199 -28.299 28.735  1   72.02  ? 394 LEU D CA  1 
ATOM   8690 C  C   . LEU D 2 224 ? -53.202 -29.19  29.46   1   76.16  ? 394 LEU D C   1 
ATOM   8691 O  O   . LEU D 2 224 ? -53.124 -29.371 30.673  1   76.49  ? 394 LEU D O   1 
ATOM   8692 C  CB  . LEU D 2 224 ? -52.775 -26.921 28.42   1   72.54  ? 394 LEU D CB  1 
ATOM   8693 C  CG  . LEU D 2 224 ? -52.912 -25.942 29.596  1   71.32  ? 394 LEU D CG  1 
ATOM   8694 C  CD1 . LEU D 2 224 ? -51.576 -25.673 30.292  1   67.47  ? 394 LEU D CD1 1 
ATOM   8695 C  CD2 . LEU D 2 224 ? -53.554 -24.624 29.147  1   68.22  ? 394 LEU D CD2 1 
ATOM   8696 N  N   . HIS D 2 225 ? -54.133 -29.769 28.697  1   80.57  ? 395 HIS D N   1 
ATOM   8697 C  CA  . HIS D 2 225 ? -55.042 -30.782 29.205  1   83.22  ? 395 HIS D CA  1 
ATOM   8698 C  C   . HIS D 2 225 ? -54.264 -31.895 29.905  1   81.78  ? 395 HIS D C   1 
ATOM   8699 O  O   . HIS D 2 225 ? -54.626 -32.296 31.011  1   86.25  ? 395 HIS D O   1 
ATOM   8700 C  CB  . HIS D 2 225 ? -55.86  -31.388 28.06   1   90.67  ? 395 HIS D CB  1 
ATOM   8701 C  CG  . HIS D 2 225 ? -57.032 -32.23  28.47   1   92.06  ? 395 HIS D CG  1 
ATOM   8702 N  ND1 . HIS D 2 225 ? -57.778 -31.997 29.607  1   89.84  ? 395 HIS D ND1 1 
ATOM   8703 C  CD2 . HIS D 2 225 ? -57.595 -33.272 27.855  1   91.5   ? 395 HIS D CD2 1 
ATOM   8704 C  CE1 . HIS D 2 225 ? -58.766 -32.871 29.67   1   92.75  ? 395 HIS D CE1 1 
ATOM   8705 N  NE2 . HIS D 2 225 ? -58.679 -33.652 28.61   1   96.3   ? 395 HIS D NE2 1 
ATOM   8706 N  N   . GLN D 2 226 ? -53.214 -32.397 29.24   1   78.25  ? 396 GLN D N   1 
ATOM   8707 C  CA  . GLN D 2 226 ? -52.408 -33.499 29.747  1   85.49  ? 396 GLN D CA  1 
ATOM   8708 C  C   . GLN D 2 226 ? -51.738 -33.067 31.054  1   85.25  ? 396 GLN D C   1 
ATOM   8709 O  O   . GLN D 2 226 ? -51.745 -33.81  32.03   1   86.08  ? 396 GLN D O   1 
ATOM   8710 C  CB  . GLN D 2 226 ? -51.455 -34.022 28.664  1   87.26  ? 396 GLN D CB  1 
ATOM   8711 C  CG  . GLN D 2 226 ? -51.086 -35.495 28.785  1   95.76  ? 396 GLN D CG  1 
ATOM   8712 C  CD  . GLN D 2 226 ? -52.29  -36.421 28.918  1   117.8  ? 396 GLN D CD  1 
ATOM   8713 O  OE1 . GLN D 2 226 ? -53.27  -36.341 28.163  1   116.25 ? 396 GLN D OE1 1 
ATOM   8714 N  NE2 . GLN D 2 226 ? -52.245 -37.33  29.886  1   122.29 ? 396 GLN D NE2 1 
ATOM   8715 N  N   . THR D 2 227 ? -51.199 -31.838 31.074  1   82.84  ? 397 THR D N   1 
ATOM   8716 C  CA  . THR D 2 227 ? -50.564 -31.265 32.256  1   83.09  ? 397 THR D CA  1 
ATOM   8717 C  C   . THR D 2 227 ? -51.567 -31.217 33.413  1   85.19  ? 397 THR D C   1 
ATOM   8718 O  O   . THR D 2 227 ? -51.225 -31.569 34.542  1   85.11  ? 397 THR D O   1 
ATOM   8719 C  CB  . THR D 2 227 ? -49.967 -29.886 31.955  1   79.24  ? 397 THR D CB  1 
ATOM   8720 O  OG1 . THR D 2 227 ? -49     -30.035 30.922  1   76.8   ? 397 THR D OG1 1 
ATOM   8721 C  CG2 . THR D 2 227 ? -49.3   -29.24  33.16   1   75.34  ? 397 THR D CG2 1 
ATOM   8722 N  N   . TYR D 2 228 ? -52.805 -30.785 33.119  1   83.64  ? 398 TYR D N   1 
ATOM   8723 C  CA  . TYR D 2 228 ? -53.845 -30.609 34.123  1   82.69  ? 398 TYR D CA  1 
ATOM   8724 C  C   . TYR D 2 228 ? -54.149 -31.959 34.769  1   89.29  ? 398 TYR D C   1 
ATOM   8725 O  O   . TYR D 2 228 ? -54.309 -32.033 35.988  1   91.11  ? 398 TYR D O   1 
ATOM   8726 C  CB  . TYR D 2 228 ? -55.062 -29.935 33.476  1   81.54  ? 398 TYR D CB  1 
ATOM   8727 C  CG  . TYR D 2 228 ? -56.18  -29.483 34.409  1   85.56  ? 398 TYR D CG  1 
ATOM   8728 C  CD1 . TYR D 2 228 ? -56.074 -29.601 35.795  1   88.28  ? 398 TYR D CD1 1 
ATOM   8729 C  CD2 . TYR D 2 228 ? -57.341 -28.9   33.902  1   86.94  ? 398 TYR D CD2 1 
ATOM   8730 C  CE1 . TYR D 2 228 ? -57.1   -29.197 36.639  1   89.87  ? 398 TYR D CE1 1 
ATOM   8731 C  CE2 . TYR D 2 228 ? -58.37  -28.481 34.743  1   89.75  ? 398 TYR D CE2 1 
ATOM   8732 C  CZ  . TYR D 2 228 ? -58.249 -28.62  36.119  1   88.83  ? 398 TYR D CZ  1 
ATOM   8733 O  OH  . TYR D 2 228 ? -59.238 -28.2   36.972  1   86.31  ? 398 TYR D OH  1 
ATOM   8734 N  N   . LEU D 2 229 ? -54.205 -33.01  33.932  1   91.39  ? 399 LEU D N   1 
ATOM   8735 C  CA  . LEU D 2 229 ? -54.578 -34.364 34.312  1   90.86  ? 399 LEU D CA  1 
ATOM   8736 C  C   . LEU D 2 229 ? -53.495 -35.013 35.175  1   92.05  ? 399 LEU D C   1 
ATOM   8737 O  O   . LEU D 2 229 ? -53.814 -35.763 36.092  1   90.46  ? 399 LEU D O   1 
ATOM   8738 C  CB  . LEU D 2 229 ? -54.844 -35.183 33.048  1   90.7   ? 399 LEU D CB  1 
ATOM   8739 C  CG  . LEU D 2 229 ? -56.143 -34.91  32.274  1   88.04  ? 399 LEU D CG  1 
ATOM   8740 C  CD1 . LEU D 2 229 ? -56.087 -35.591 30.917  1   86.9   ? 399 LEU D CD1 1 
ATOM   8741 C  CD2 . LEU D 2 229 ? -57.373 -35.383 33.01   1   86.94  ? 399 LEU D CD2 1 
ATOM   8742 N  N   . ARG D 2 230 ? -52.219 -34.718 34.89   1   96.24  ? 400 ARG D N   1 
ATOM   8743 C  CA  . ARG D 2 230 ? -51.089 -35.346 35.566  1   97.6   ? 400 ARG D CA  1 
ATOM   8744 C  C   . ARG D 2 230 ? -50.677 -34.531 36.795  1   91.12  ? 400 ARG D C   1 
ATOM   8745 O  O   . ARG D 2 230 ? -49.845 -34.989 37.582  1   92.09  ? 400 ARG D O   1 
ATOM   8746 C  CB  . ARG D 2 230 ? -49.977 -35.601 34.535  1   100.01 ? 400 ARG D CB  1 
ATOM   8747 C  CG  . ARG D 2 230 ? -50.368 -36.671 33.52   1   110.83 ? 400 ARG D CG  1 
ATOM   8748 C  CD  . ARG D 2 230 ? -49.789 -36.559 32.106  1   118.13 ? 400 ARG D CD  1 
ATOM   8749 N  NE  . ARG D 2 230 ? -49.75  -37.894 31.488  1   130.95 ? 400 ARG D NE  1 
ATOM   8750 C  CZ  . ARG D 2 230 ? -49.157 -38.29  30.352  1   128.43 ? 400 ARG D CZ  1 
ATOM   8751 N  NH1 . ARG D 2 230 ? -48.48  -37.431 29.597  1   121.15 ? 400 ARG D NH1 1 
ATOM   8752 N  NH2 . ARG D 2 230 ? -49.252 -39.561 29.978  1   122.25 ? 400 ARG D NH2 1 
ATOM   8753 N  N   . ALA D 2 231 ? -51.313 -33.361 36.975  1   85.75  ? 401 ALA D N   1 
ATOM   8754 C  CA  . ALA D 2 231 ? -50.888 -32.341 37.928  1   84.41  ? 401 ALA D CA  1 
ATOM   8755 C  C   . ALA D 2 231 ? -50.719 -32.889 39.345  1   86.15  ? 401 ALA D C   1 
ATOM   8756 O  O   . ALA D 2 231 ? -49.713 -32.585 39.986  1   89.03  ? 401 ALA D O   1 
ATOM   8757 C  CB  . ALA D 2 231 ? -51.805 -31.133 37.9    1   82.15  ? 401 ALA D CB  1 
ATOM   8758 N  N   . PRO D 2 232 ? -51.681 -33.671 39.899  1   89.2   ? 402 PRO D N   1 
ATOM   8759 C  CA  . PRO D 2 232 ? -51.507 -34.271 41.227  1   89.1   ? 402 PRO D CA  1 
ATOM   8760 C  C   . PRO D 2 232 ? -50.281 -35.168 41.412  1   89.58  ? 402 PRO D C   1 
ATOM   8761 O  O   . PRO D 2 232 ? -49.892 -35.434 42.546  1   88.93  ? 402 PRO D O   1 
ATOM   8762 C  CB  . PRO D 2 232 ? -52.819 -35.046 41.459  1   87.79  ? 402 PRO D CB  1 
ATOM   8763 C  CG  . PRO D 2 232 ? -53.81  -34.365 40.555  1   87.54  ? 402 PRO D CG  1 
ATOM   8764 C  CD  . PRO D 2 232 ? -53.011 -33.955 39.33   1   86.89  ? 402 PRO D CD  1 
ATOM   8765 N  N   . GLN D 2 233 ? -49.688 -35.641 40.302  1   90.51  ? 403 GLN D N   1 
ATOM   8766 C  CA  . GLN D 2 233 ? -48.533 -36.534 40.339  1   91.13  ? 403 GLN D CA  1 
ATOM   8767 C  C   . GLN D 2 233 ? -47.244 -35.834 39.906  1   85.19  ? 403 GLN D C   1 
ATOM   8768 O  O   . GLN D 2 233 ? -46.189 -36.469 39.899  1   83.98  ? 403 GLN D O   1 
ATOM   8769 C  CB  . GLN D 2 233 ? -48.676 -37.776 39.452  1   96.4   ? 403 GLN D CB  1 
ATOM   8770 C  CG  . GLN D 2 233 ? -49.411 -38.955 40.08   1   99     ? 403 GLN D CG  1 
ATOM   8771 C  CD  . GLN D 2 233 ? -50.91  -38.778 40.045  1   104.96 ? 403 GLN D CD  1 
ATOM   8772 O  OE1 . GLN D 2 233 ? -51.588 -38.935 41.061  1   115.29 ? 403 GLN D OE1 1 
ATOM   8773 N  NE2 . GLN D 2 233 ? -51.45  -38.456 38.877  1   102.91 ? 403 GLN D NE2 1 
ATOM   8774 N  N   . HIS D 2 234 ? -47.325 -34.541 39.556  1   81.21  ? 404 HIS D N   1 
ATOM   8775 C  CA  . HIS D 2 234 ? -46.154 -33.751 39.206  1   74.46  ? 404 HIS D CA  1 
ATOM   8776 C  C   . HIS D 2 234 ? -45.223 -33.697 40.423  1   72.45  ? 404 HIS D C   1 
ATOM   8777 O  O   . HIS D 2 234 ? -45.693 -33.581 41.554  1   74.27  ? 404 HIS D O   1 
ATOM   8778 C  CB  . HIS D 2 234 ? -46.584 -32.355 38.73   1   75.51  ? 404 HIS D CB  1 
ATOM   8779 C  CG  . HIS D 2 234 ? -45.53  -31.677 37.908  1   78.36  ? 404 HIS D CG  1 
ATOM   8780 N  ND1 . HIS D 2 234 ? -44.273 -31.357 38.392  1   76.21  ? 404 HIS D ND1 1 
ATOM   8781 C  CD2 . HIS D 2 234 ? -45.528 -31.317 36.622  1   76.93  ? 404 HIS D CD2 1 
ATOM   8782 C  CE1 . HIS D 2 234 ? -43.543 -30.821 37.427  1   74.61  ? 404 HIS D CE1 1 
ATOM   8783 N  NE2 . HIS D 2 234 ? -44.287 -30.788 36.34   1   78.52  ? 404 HIS D NE2 1 
ATOM   8784 N  N   . ALA D 2 235 ? -43.903 -33.764 40.201  1   67.05  ? 405 ALA D N   1 
ATOM   8785 C  CA  . ALA D 2 235 ? -42.945 -33.667 41.29   1   66.49  ? 405 ALA D CA  1 
ATOM   8786 C  C   . ALA D 2 235 ? -43.028 -32.296 41.971  1   68.37  ? 405 ALA D C   1 
ATOM   8787 O  O   . ALA D 2 235 ? -42.559 -32.146 43.096  1   71.07  ? 405 ALA D O   1 
ATOM   8788 C  CB  . ALA D 2 235 ? -41.544 -33.956 40.787  1   62.42  ? 405 ALA D CB  1 
ATOM   8789 N  N   . GLN D 2 236 ? -43.61  -31.302 41.281  1   68.27  ? 406 GLN D N   1 
ATOM   8790 C  CA  . GLN D 2 236 ? -43.764 -29.933 41.767  1   72.36  ? 406 GLN D CA  1 
ATOM   8791 C  C   . GLN D 2 236 ? -45.245 -29.62  42.014  1   75.48  ? 406 GLN D C   1 
ATOM   8792 O  O   . GLN D 2 236 ? -46.082 -29.689 41.1    1   79.76  ? 406 GLN D O   1 
ATOM   8793 C  CB  . GLN D 2 236 ? -43.114 -28.935 40.803  1   68.19  ? 406 GLN D CB  1 
ATOM   8794 C  CG  . GLN D 2 236 ? -41.609 -28.763 40.987  1   69.54  ? 406 GLN D CG  1 
ATOM   8795 C  CD  . GLN D 2 236 ? -40.774 -29.939 40.534  1   78.93  ? 406 GLN D CD  1 
ATOM   8796 O  OE1 . GLN D 2 236 ? -41.032 -30.542 39.482  1   93     ? 406 GLN D OE1 1 
ATOM   8797 N  NE2 . GLN D 2 236 ? -39.742 -30.245 41.312  1   75.22  ? 406 GLN D NE2 1 
ATOM   8798 N  N   . GLN D 2 237 ? -45.53  -29.241 43.271  1   73.33  ? 407 GLN D N   1 
ATOM   8799 C  CA  . GLN D 2 237 ? -46.865 -29.176 43.841  1   76.74  ? 407 GLN D CA  1 
ATOM   8800 C  C   . GLN D 2 237 ? -47.249 -27.772 44.316  1   78.96  ? 407 GLN D C   1 
ATOM   8801 O  O   . GLN D 2 237 ? -48.438 -27.526 44.52   1   84.31  ? 407 GLN D O   1 
ATOM   8802 C  CB  . GLN D 2 237 ? -46.941 -30.132 45.034  1   78.08  ? 407 GLN D CB  1 
ATOM   8803 C  CG  . GLN D 2 237 ? -47.04  -31.601 44.642  1   77.16  ? 407 GLN D CG  1 
ATOM   8804 C  CD  . GLN D 2 237 ? -48.104 -31.826 43.594  1   78.47  ? 407 GLN D CD  1 
ATOM   8805 O  OE1 . GLN D 2 237 ? -49.259 -31.396 43.737  1   79.58  ? 407 GLN D OE1 1 
ATOM   8806 N  NE2 . GLN D 2 237 ? -47.703 -32.463 42.503  1   80.4   ? 407 GLN D NE2 1 
ATOM   8807 N  N   . SER D 2 238 ? -46.265 -26.865 44.466  1   75.29  ? 408 SER D N   1 
ATOM   8808 C  CA  . SER D 2 238 ? -46.469 -25.545 45.06   1   75.82  ? 408 SER D CA  1 
ATOM   8809 C  C   . SER D 2 238 ? -47.65  -24.787 44.443  1   74.09  ? 408 SER D C   1 
ATOM   8810 O  O   . SER D 2 238 ? -48.348 -24.057 45.144  1   73.76  ? 408 SER D O   1 
ATOM   8811 C  CB  . SER D 2 238 ? -45.217 -24.692 45.032  1   72.62  ? 408 SER D CB  1 
ATOM   8812 O  OG  . SER D 2 238 ? -44.122 -25.322 45.673  1   76.2   ? 408 SER D OG  1 
ATOM   8813 N  N   . ILE D 2 239 ? -47.86  -24.926 43.128  1   71.11  ? 409 ILE D N   1 
ATOM   8814 C  CA  . ILE D 2 239 ? -48.936 -24.191 42.484  1   70.61  ? 409 ILE D CA  1 
ATOM   8815 C  C   . ILE D 2 239 ? -50.286 -24.805 42.854  1   77.74  ? 409 ILE D C   1 
ATOM   8816 O  O   . ILE D 2 239 ? -51.25  -24.068 43.083  1   80.67  ? 409 ILE D O   1 
ATOM   8817 C  CB  . ILE D 2 239 ? -48.722 -24.059 40.967  1   69.74  ? 409 ILE D CB  1 
ATOM   8818 C  CG1 . ILE D 2 239 ? -47.403 -23.383 40.618  1   64.64  ? 409 ILE D CG1 1 
ATOM   8819 C  CG2 . ILE D 2 239 ? -49.883 -23.318 40.32   1   68.13  ? 409 ILE D CG2 1 
ATOM   8820 C  CD1 . ILE D 2 239 ? -46.995 -23.533 39.163  1   61.93  ? 409 ILE D CD1 1 
ATOM   8821 N  N   . ARG D 2 240 ? -50.331 -26.137 42.988  1   79.95  ? 410 ARG D N   1 
ATOM   8822 C  CA  . ARG D 2 240 ? -51.548 -26.817 43.418  1   85.83  ? 410 ARG D CA  1 
ATOM   8823 C  C   . ARG D 2 240 ? -51.94  -26.398 44.836  1   89.85  ? 410 ARG D C   1 
ATOM   8824 O  O   . ARG D 2 240 ? -53.122 -26.171 45.101  1   94.17  ? 410 ARG D O   1 
ATOM   8825 C  CB  . ARG D 2 240 ? -51.446 -28.339 43.272  1   87.21  ? 410 ARG D CB  1 
ATOM   8826 C  CG  . ARG D 2 240 ? -51.916 -28.852 41.918  1   88.92  ? 410 ARG D CG  1 
ATOM   8827 C  CD  . ARG D 2 240 ? -51.649 -30.341 41.691  1   99.06  ? 410 ARG D CD  1 
ATOM   8828 N  NE  . ARG D 2 240 ? -52.815 -31.182 41.994  1   102.42 ? 410 ARG D NE  1 
ATOM   8829 C  CZ  . ARG D 2 240 ? -53.166 -31.611 43.203  1   101.99 ? 410 ARG D CZ  1 
ATOM   8830 N  NH1 . ARG D 2 240 ? -54.436 -31.564 43.529  1   102.44 ? 410 ARG D NH1 1 
ATOM   8831 N  NH2 . ARG D 2 240 ? -52.278 -31.917 44.131  1   100.99 ? 410 ARG D NH2 1 
ATOM   8832 N  N   . GLU D 2 241 ? -50.95  -26.278 45.729  1   88.91  ? 411 GLU D N   1 
ATOM   8833 C  CA  . GLU D 2 241 ? -51.165 -25.845 47.103  1   91.85  ? 411 GLU D CA  1 
ATOM   8834 C  C   . GLU D 2 241 ? -51.686 -24.413 47.163  1   92.3   ? 411 GLU D C   1 
ATOM   8835 O  O   . GLU D 2 241 ? -52.408 -24.07  48.094  1   99.93  ? 411 GLU D O   1 
ATOM   8836 C  CB  . GLU D 2 241 ? -49.848 -25.81  47.869  1   89.02  ? 411 GLU D CB  1 
ATOM   8837 C  CG  . GLU D 2 241 ? -49.018 -27.069 47.64   1   103.46 ? 411 GLU D CG  1 
ATOM   8838 C  CD  . GLU D 2 241 ? -49.235 -28.087 48.756  1   111.82 ? 411 GLU D CD  1 
ATOM   8839 O  OE1 . GLU D 2 241 ? -50.381 -28.318 49.237  1   108.57 ? 411 GLU D OE1 1 
ATOM   8840 O  OE2 . GLU D 2 241 ? -48.198 -28.685 49.135  1   116.85 ? 411 GLU D OE2 1 
ATOM   8841 N  N   . LYS D 2 242 ? -51.31  -23.586 46.181  1   83.05  ? 412 LYS D N   1 
ATOM   8842 C  CA  . LYS D 2 242 ? -51.615 -22.166 46.246  1   78.67  ? 412 LYS D CA  1 
ATOM   8843 C  C   . LYS D 2 242 ? -53.057 -21.921 45.807  1   81.9   ? 412 LYS D C   1 
ATOM   8844 O  O   . LYS D 2 242 ? -53.742 -21.101 46.407  1   84.25  ? 412 LYS D O   1 
ATOM   8845 C  CB  . LYS D 2 242 ? -50.549 -21.406 45.45   1   71.01  ? 412 LYS D CB  1 
ATOM   8846 C  CG  . LYS D 2 242 ? -51.008 -20.166 44.708  1   64.01  ? 412 LYS D CG  1 
ATOM   8847 C  CD  . LYS D 2 242 ? -49.824 -19.442 44.093  1   58.07  ? 412 LYS D CD  1 
ATOM   8848 C  CE  . LYS D 2 242 ? -50.147 -18.155 43.38   1   56.92  ? 412 LYS D CE  1 
ATOM   8849 N  NZ  . LYS D 2 242 ? -49.044 -17.782 42.488  1   49.02  ? 412 LYS D NZ  1 
ATOM   8850 N  N   . TYR D 2 243 ? -53.505 -22.664 44.785  1   84.77  ? 413 TYR D N   1 
ATOM   8851 C  CA  . TYR D 2 243 ? -54.815 -22.479 44.174  1   82.32  ? 413 TYR D CA  1 
ATOM   8852 C  C   . TYR D 2 243 ? -55.888 -23.324 44.873  1   83.41  ? 413 TYR D C   1 
ATOM   8853 O  O   . TYR D 2 243 ? -57.025 -23.376 44.395  1   84.56  ? 413 TYR D O   1 
ATOM   8854 C  CB  . TYR D 2 243 ? -54.7   -22.654 42.653  1   76.35  ? 413 TYR D CB  1 
ATOM   8855 C  CG  . TYR D 2 243 ? -54.144 -21.437 41.936  1   75.46  ? 413 TYR D CG  1 
ATOM   8856 C  CD1 . TYR D 2 243 ? -52.774 -21.183 41.901  1   76.71  ? 413 TYR D CD1 1 
ATOM   8857 C  CD2 . TYR D 2 243 ? -54.993 -20.526 41.31   1   78.75  ? 413 TYR D CD2 1 
ATOM   8858 C  CE1 . TYR D 2 243 ? -52.263 -20.068 41.25   1   69.09  ? 413 TYR D CE1 1 
ATOM   8859 C  CE2 . TYR D 2 243 ? -54.496 -19.403 40.666  1   73.65  ? 413 TYR D CE2 1 
ATOM   8860 C  CZ  . TYR D 2 243 ? -53.131 -19.184 40.639  1   70.68  ? 413 TYR D CZ  1 
ATOM   8861 O  OH  . TYR D 2 243 ? -52.634 -18.099 40      1   77.21  ? 413 TYR D OH  1 
ATOM   8862 N  N   . LYS D 2 244 ? -55.533 -23.954 46.004  1   84.18  ? 414 LYS D N   1 
ATOM   8863 C  CA  . LYS D 2 244 ? -56.505 -24.585 46.893  1   91.9   ? 414 LYS D CA  1 
ATOM   8864 C  C   . LYS D 2 244 ? -57.165 -23.537 47.78   1   93.92  ? 414 LYS D C   1 
ATOM   8865 O  O   . LYS D 2 244 ? -58.323 -23.71  48.154  1   98.22  ? 414 LYS D O   1 
ATOM   8866 C  CB  . LYS D 2 244 ? -55.874 -25.598 47.853  1   94.44  ? 414 LYS D CB  1 
ATOM   8867 C  CG  . LYS D 2 244 ? -55.674 -27.015 47.332  1   105.32 ? 414 LYS D CG  1 
ATOM   8868 C  CD  . LYS D 2 244 ? -54.404 -27.659 47.878  1   108.73 ? 414 LYS D CD  1 
ATOM   8869 C  CE  . LYS D 2 244 ? -54.213 -29.069 47.387  1   111.3  ? 414 LYS D CE  1 
ATOM   8870 N  NZ  . LYS D 2 244 ? -53.659 -29.969 48.397  1   108.58 ? 414 LYS D NZ  1 
ATOM   8871 N  N   . ASN D 2 245 ? -56.409 -22.48  48.121  1   93.07  ? 415 ASN D N   1 
ATOM   8872 C  CA  . ASN D 2 245 ? -56.833 -21.438 49.049  1   103.23 ? 415 ASN D CA  1 
ATOM   8873 C  C   . ASN D 2 245 ? -58.07  -20.713 48.502  1   109.84 ? 415 ASN D C   1 
ATOM   8874 O  O   . ASN D 2 245 ? -58.269 -20.63  47.285  1   111.16 ? 415 ASN D O   1 
ATOM   8875 C  CB  . ASN D 2 245 ? -55.661 -20.516 49.385  1   110.76 ? 415 ASN D CB  1 
ATOM   8876 C  CG  . ASN D 2 245 ? -55.984 -19.376 50.331  1   129.8  ? 415 ASN D CG  1 
ATOM   8877 O  OD1 . ASN D 2 245 ? -56.964 -18.646 50.148  1   135.9  ? 415 ASN D OD1 1 
ATOM   8878 N  ND2 . ASN D 2 245 ? -55.15  -19.177 51.341  1   136.43 ? 415 ASN D ND2 1 
ATOM   8879 N  N   . SER D 2 246 ? -58.888 -20.174 49.423  1   107.26 ? 416 SER D N   1 
ATOM   8880 C  CA  . SER D 2 246 ? -60.096 -19.435 49.085  1   103.51 ? 416 SER D CA  1 
ATOM   8881 C  C   . SER D 2 246 ? -59.772 -18.173 48.29   1   99.89  ? 416 SER D C   1 
ATOM   8882 O  O   . SER D 2 246 ? -60.639 -17.649 47.592  1   104.97 ? 416 SER D O   1 
ATOM   8883 C  CB  . SER D 2 246 ? -60.893 -19.114 50.32   1   100.09 ? 416 SER D CB  1 
ATOM   8884 O  OG  . SER D 2 246 ? -60.153 -18.248 51.168  1   101.59 ? 416 SER D OG  1 
ATOM   8885 N  N   . LYS D 2 247 ? -58.531 -17.684 48.425  1   94.51  ? 417 LYS D N   1 
ATOM   8886 C  CA  . LYS D 2 247 ? -58.083 -16.54  47.653  1   92.11  ? 417 LYS D CA  1 
ATOM   8887 C  C   . LYS D 2 247 ? -58.282 -16.865 46.177  1   93.07  ? 417 LYS D C   1 
ATOM   8888 O  O   . LYS D 2 247 ? -58.692 -15.991 45.425  1   91.45  ? 417 LYS D O   1 
ATOM   8889 C  CB  . LYS D 2 247 ? -56.644 -16.173 48.037  1   91.46  ? 417 LYS D CB  1 
ATOM   8890 C  CG  . LYS D 2 247 ? -55.794 -15.505 46.967  1   88.38  ? 417 LYS D CG  1 
ATOM   8891 C  CD  . LYS D 2 247 ? -54.338 -15.47  47.42   1   96.22  ? 417 LYS D CD  1 
ATOM   8892 C  CE  . LYS D 2 247 ? -53.997 -14.655 48.63   1   97.3   ? 417 LYS D CE  1 
ATOM   8893 N  NZ  . LYS D 2 247 ? -53.569 -13.323 48.196  1   95.94  ? 417 LYS D NZ  1 
ATOM   8894 N  N   . TYR D 2 248 ? -58.054 -18.139 45.808  1   93.96  ? 418 TYR D N   1 
ATOM   8895 C  CA  . TYR D 2 248 ? -58.175 -18.601 44.43   1   92.84  ? 418 TYR D CA  1 
ATOM   8896 C  C   . TYR D 2 248 ? -59.413 -19.487 44.237  1   98.75  ? 418 TYR D C   1 
ATOM   8897 O  O   . TYR D 2 248 ? -59.556 -20.089 43.174  1   101.87 ? 418 TYR D O   1 
ATOM   8898 C  CB  . TYR D 2 248 ? -56.872 -19.248 43.937  1   84.08  ? 418 TYR D CB  1 
ATOM   8899 C  CG  . TYR D 2 248 ? -55.653 -18.344 44.051  1   78.9   ? 418 TYR D CG  1 
ATOM   8900 C  CD1 . TYR D 2 248 ? -55.569 -17.173 43.302  1   76.67  ? 418 TYR D CD1 1 
ATOM   8901 C  CD2 . TYR D 2 248 ? -54.595 -18.656 44.908  1   76.6   ? 418 TYR D CD2 1 
ATOM   8902 C  CE1 . TYR D 2 248 ? -54.475 -16.326 43.417  1   72.5   ? 418 TYR D CE1 1 
ATOM   8903 C  CE2 . TYR D 2 248 ? -53.496 -17.818 45.021  1   76.26  ? 418 TYR D CE2 1 
ATOM   8904 C  CZ  . TYR D 2 248 ? -53.438 -16.643 44.283  1   74.94  ? 418 TYR D CZ  1 
ATOM   8905 O  OH  . TYR D 2 248 ? -52.35  -15.813 44.408  1   78.83  ? 418 TYR D OH  1 
ATOM   8906 N  N   . HIS D 2 249 ? -60.288 -19.582 45.255  1   98.79  ? 419 HIS D N   1 
ATOM   8907 C  CA  . HIS D 2 249 ? -61.575 -20.275 45.167  1   102.83 ? 419 HIS D CA  1 
ATOM   8908 C  C   . HIS D 2 249 ? -61.403 -21.786 45.006  1   98.78  ? 419 HIS D C   1 
ATOM   8909 O  O   . HIS D 2 249 ? -62.219 -22.415 44.329  1   99.32  ? 419 HIS D O   1 
ATOM   8910 C  CB  . HIS D 2 249 ? -62.456 -19.682 44.055  1   110.91 ? 419 HIS D CB  1 
ATOM   8911 C  CG  . HIS D 2 249 ? -62.519 -18.188 44.072  1   119.77 ? 419 HIS D CG  1 
ATOM   8912 N  ND1 . HIS D 2 249 ? -62.545 -17.397 42.941  1   121.87 ? 419 HIS D ND1 1 
ATOM   8913 C  CD2 . HIS D 2 249 ? -62.543 -17.343 45.112  1   122.78 ? 419 HIS D CD2 1 
ATOM   8914 C  CE1 . HIS D 2 249 ? -62.587 -16.12  43.304  1   117.23 ? 419 HIS D CE1 1 
ATOM   8915 N  NE2 . HIS D 2 249 ? -62.598 -16.065 44.617  1   118.08 ? 419 HIS D NE2 1 
ATOM   8916 N  N   . GLY D 2 250 ? -60.353 -22.342 45.636  1   97.39  ? 420 GLY D N   1 
ATOM   8917 C  CA  . GLY D 2 250 ? -60.054 -23.768 45.669  1   97.24  ? 420 GLY D CA  1 
ATOM   8918 C  C   . GLY D 2 250 ? -60.062 -24.461 44.305  1   96.67  ? 420 GLY D C   1 
ATOM   8919 O  O   . GLY D 2 250 ? -60.325 -25.662 44.242  1   101.52 ? 420 GLY D O   1 
ATOM   8920 N  N   . VAL D 2 251 ? -59.722 -23.734 43.233  1   90.43  ? 421 VAL D N   1 
ATOM   8921 C  CA  . VAL D 2 251 ? -59.896 -24.238 41.875  1   90.54  ? 421 VAL D CA  1 
ATOM   8922 C  C   . VAL D 2 251 ? -58.979 -25.43  41.571  1   93     ? 421 VAL D C   1 
ATOM   8923 O  O   . VAL D 2 251 ? -59.22  -26.128 40.581  1   99.8   ? 421 VAL D O   1 
ATOM   8924 C  CB  . VAL D 2 251 ? -59.746 -23.14  40.802  1   86.49  ? 421 VAL D CB  1 
ATOM   8925 C  CG1 . VAL D 2 251 ? -60.9   -22.143 40.86   1   86.52  ? 421 VAL D CG1 1 
ATOM   8926 C  CG2 . VAL D 2 251 ? -58.393 -22.434 40.885  1   81.83  ? 421 VAL D CG2 1 
ATOM   8927 N  N   . SER D 2 252 ? -57.918 -25.639 42.378  1   89.34  ? 422 SER D N   1 
ATOM   8928 C  CA  . SER D 2 252 ? -56.978 -26.739 42.174  1   84.77  ? 422 SER D CA  1 
ATOM   8929 C  C   . SER D 2 252 ? -57.597 -28.069 42.611  1   87.19  ? 422 SER D C   1 
ATOM   8930 O  O   . SER D 2 252 ? -57.161 -29.122 42.171  1   87.2   ? 422 SER D O   1 
ATOM   8931 C  CB  . SER D 2 252 ? -55.638 -26.496 42.851  1   79.72  ? 422 SER D CB  1 
ATOM   8932 O  OG  . SER D 2 252 ? -55.736 -26.595 44.263  1   88.08  ? 422 SER D OG  1 
ATOM   8933 N  N   . LEU D 2 253 ? -58.59  -28.008 43.502  1   90.55  ? 423 LEU D N   1 
ATOM   8934 C  CA  . LEU D 2 253 ? -59.291 -29.186 43.979  1   95.32  ? 423 LEU D CA  1 
ATOM   8935 C  C   . LEU D 2 253 ? -60.293 -29.677 42.942  1   100.05 ? 423 LEU D C   1 
ATOM   8936 O  O   . LEU D 2 253 ? -60.526 -30.869 42.881  1   105.71 ? 423 LEU D O   1 
ATOM   8937 C  CB  . LEU D 2 253 ? -59.942 -28.921 45.332  1   94.17  ? 423 LEU D CB  1 
ATOM   8938 C  CG  . LEU D 2 253 ? -58.971 -28.564 46.464  1   91.42  ? 423 LEU D CG  1 
ATOM   8939 C  CD1 . LEU D 2 253 ? -59.721 -27.98  47.65   1   91.18  ? 423 LEU D CD1 1 
ATOM   8940 C  CD2 . LEU D 2 253 ? -58.141 -29.766 46.891  1   89.97  ? 423 LEU D CD2 1 
ATOM   8941 N  N   . LEU D 2 254 ? -60.779 -28.764 42.102  1   101.75 ? 424 LEU D N   1 
ATOM   8942 C  CA  . LEU D 2 254 ? -61.747 -29.129 41.04   1   104.87 ? 424 LEU D CA  1 
ATOM   8943 C  C   . LEU D 2 254 ? -61.16  -30.251 40.183  1   109.78 ? 424 LEU D C   1 
ATOM   8944 O  O   . LEU D 2 254 ? -59.966 -30.177 39.841  1   114.56 ? 424 LEU D O   1 
ATOM   8945 C  CB  . LEU D 2 254 ? -62.098 -27.917 40.184  1   102.97 ? 424 LEU D CB  1 
ATOM   8946 C  CG  . LEU D 2 254 ? -62.601 -26.686 40.941  1   108.81 ? 424 LEU D CG  1 
ATOM   8947 C  CD1 . LEU D 2 254 ? -63.13  -25.646 39.972  1   103.24 ? 424 LEU D CD1 1 
ATOM   8948 C  CD2 . LEU D 2 254 ? -63.661 -27.059 41.961  1   107.85 ? 424 LEU D CD2 1 
ATOM   8949 N  N   . ASN D 2 255 ? -61.988 -31.23  39.83   1   115.12 ? 425 ASN D N   1 
ATOM   8950 C  CA  . ASN D 2 255 ? -61.517 -32.389 39.031  1   114.17 ? 425 ASN D CA  1 
ATOM   8951 C  C   . ASN D 2 255 ? -61.534 -32.011 37.549  1   113.26 ? 425 ASN D C   1 
ATOM   8952 O  O   . ASN D 2 255 ? -62.552 -31.469 37.079  1   114.93 ? 425 ASN D O   1 
ATOM   8953 C  CB  . ASN D 2 255 ? -62.347 -33.625 39.351  1   116.55 ? 425 ASN D CB  1 
ATOM   8954 C  CG  . ASN D 2 255 ? -62.681 -33.711 40.819  1   121.19 ? 425 ASN D CG  1 
ATOM   8955 O  OD1 . ASN D 2 255 ? -63.848 -33.573 41.2    1   123.43 ? 425 ASN D OD1 1 
ATOM   8956 N  ND2 . ASN D 2 255 ? -61.677 -33.933 41.655  1   123.3  ? 425 ASN D ND2 1 
ATOM   8957 N  N   . PRO D 2 256 ? -60.443 -32.273 36.802  1   107.95 ? 426 PRO D N   1 
ATOM   8958 C  CA  . PRO D 2 256 ? -60.38  -31.894 35.4    1   103.69 ? 426 PRO D CA  1 
ATOM   8959 C  C   . PRO D 2 256 ? -61.296 -32.705 34.514  1   107.49 ? 426 PRO D C   1 
ATOM   8960 O  O   . PRO D 2 256 ? -61.629 -33.854 34.846  1   112.18 ? 426 PRO D O   1 
ATOM   8961 C  CB  . PRO D 2 256 ? -58.907 -32.147 35.067  1   101.38 ? 426 PRO D CB  1 
ATOM   8962 C  CG  . PRO D 2 256 ? -58.481 -33.227 36.028  1   104.13 ? 426 PRO D CG  1 
ATOM   8963 C  CD  . PRO D 2 256 ? -59.24  -32.913 37.298  1   105.02 ? 426 PRO D CD  1 
ATOM   8964 N  N   . PRO D 2 257 ? -61.721 -32.188 33.333  1   104.56 ? 427 PRO D N   1 
ATOM   8965 C  CA  . PRO D 2 257 ? -62.494 -32.998 32.414  1   107.82 ? 427 PRO D CA  1 
ATOM   8966 C  C   . PRO D 2 257 ? -61.59  -34.089 31.889  1   114.12 ? 427 PRO D C   1 
ATOM   8967 O  O   . PRO D 2 257 ? -60.362 -34.04  32.095  1   113.85 ? 427 PRO D O   1 
ATOM   8968 C  CB  . PRO D 2 257 ? -62.878 -32.008 31.326  1   104.84 ? 427 PRO D CB  1 
ATOM   8969 C  CG  . PRO D 2 257 ? -61.737 -31.035 31.304  1   102.58 ? 427 PRO D CG  1 
ATOM   8970 C  CD  . PRO D 2 257 ? -61.51  -30.834 32.784  1   101.96 ? 427 PRO D CD  1 
ATOM   8971 N  N   . GLU D 2 258 ? -62.172 -35.071 31.202  1   120.06 ? 428 GLU D N   1 
ATOM   8972 C  CA  . GLU D 2 258 ? -61.325 -36.122 30.587  1   119.44 ? 428 GLU D CA  1 
ATOM   8973 C  C   . GLU D 2 258 ? -61.427 -35.996 29.063  1   118.34 ? 428 GLU D C   1 
ATOM   8974 O  O   . GLU D 2 258 ? -60.668 -36.687 28.36   1   115.75 ? 428 GLU D O   1 
ATOM   8975 C  CB  . GLU D 2 258 ? -61.746 -37.49  31.116  1   123.6  ? 428 GLU D CB  1 
ATOM   8976 C  CG  . GLU D 2 258 ? -61.683 -37.587 32.636  1   127.09 ? 428 GLU D CG  1 
ATOM   8977 C  CD  . GLU D 2 258 ? -62.857 -38.329 33.245  1   138.16 ? 428 GLU D CD  1 
ATOM   8978 O  OE1 . GLU D 2 258 ? -63.09  -39.488 32.844  1   138.16 ? 428 GLU D OE1 1 
ATOM   8979 O  OE2 . GLU D 2 258 ? -63.537 -37.75  34.117  1   142.32 ? 428 GLU D OE2 1 
ATOM   8980 N  N   . THR D 2 259 ? -62.315 -35.127 28.588  1   118.05 ? 429 THR D N   1 
ATOM   8981 C  CA  . THR D 2 259 ? -62.497 -34.961 27.137  1   121.53 ? 429 THR D CA  1 
ATOM   8982 C  C   . THR D 2 259 ? -62.658 -33.497 26.821  1   124.64 ? 429 THR D C   1 
ATOM   8983 O  O   . THR D 2 259 ? -63.237 -32.777 27.654  1   129.48 ? 429 THR D O   1 
ATOM   8984 C  CB  . THR D 2 259 ? -63.711 -35.766 26.683  1   124.45 ? 429 THR D CB  1 
ATOM   8985 O  OG1 . THR D 2 259 ? -64.797 -35.236 27.437  1   124.58 ? 429 THR D OG1 1 
ATOM   8986 C  CG2 . THR D 2 259 ? -63.557 -37.252 26.952  1   123.64 ? 429 THR D CG2 1 
ATOM   8987 N  N   . LEU D 2 260 ? -62.182 -33.074 25.651  1   128.8  ? 430 LEU D N   1 
ATOM   8988 C  CA  . LEU D 2 260 ? -62.22  -31.64  25.282  1   134.62 ? 430 LEU D CA  1 
ATOM   8989 C  C   . LEU D 2 260 ? -62.816 -31.492 23.879  1   147    ? 430 LEU D C   1 
ATOM   8990 O  O   . LEU D 2 260 ? -62.398 -30.556 23.169  1   156.99 ? 430 LEU D O   1 
ATOM   8991 C  CB  . LEU D 2 260 ? -60.799 -31.084 25.31   1   123.78 ? 430 LEU D CB  1 
ATOM   8992 C  CG  . LEU D 2 260 ? -60.197 -30.8   26.688  1   123.08 ? 430 LEU D CG  1 
ATOM   8993 C  CD1 . LEU D 2 260 ? -58.958 -29.948 26.5    1   115.89 ? 430 LEU D CD1 1 
ATOM   8994 C  CD2 . LEU D 2 260 ? -61.2   -30.087 27.569  1   129.84 ? 430 LEU D CD2 1 
ATOM   8995 N  N   . ASN D 2 261 ? -63.724 -32.388 23.491  1   146.53 ? 431 ASN D N   1 
ATOM   8996 C  CA  . ASN D 2 261 ? -64.303 -32.35  22.122  1   147.05 ? 431 ASN D CA  1 
ATOM   8997 C  C   . ASN D 2 261 ? -63.16  -32.392 21.105  1   148.84 ? 431 ASN D C   1 
ATOM   8998 O  O   . ASN D 2 261 ? -62.168 -33.104 21.358  1   153.69 ? 431 ASN D O   1 
ATOM   8999 C  CB  . ASN D 2 261 ? -65.215 -31.147 21.922  1   145.83 ? 431 ASN D CB  1 
ATOM   9000 C  CG  . ASN D 2 261 ? -66.207 -31.002 23.05   1   151.41 ? 431 ASN D CG  1 
ATOM   9001 O  OD1 . ASN D 2 261 ? -66.321 -31.896 23.896  1   155.23 ? 431 ASN D OD1 1 
ATOM   9002 N  ND2 . ASN D 2 261 ? -66.927 -29.89  23.084  1   150.47 ? 431 ASN D ND2 1 
ATOM   9003 N  N   . VAL D 2 262 ? -63.297 -31.677 19.989  1   149.26 ? 432 VAL D N   1 
ATOM   9004 C  CA  . VAL D 2 262 ? -62.257 -31.761 18.923  1   143.65 ? 432 VAL D CA  1 
ATOM   9005 C  C   . VAL D 2 262 ? -61.205 -30.674 19.181  1   136.68 ? 432 VAL D C   1 
ATOM   9006 O  O   . VAL D 2 262 ? -60.246 -30.978 19.921  1   133.88 ? 432 VAL D O   1 
ATOM   9007 C  CB  . VAL D 2 262 ? -62.871 -31.628 17.519  1   147.89 ? 432 VAL D CB  1 
ATOM   9008 C  CG1 . VAL D 2 262 ? -63.871 -32.741 17.233  1   144.74 ? 432 VAL D CG1 1 
ATOM   9009 C  CG2 . VAL D 2 262 ? -63.512 -30.261 17.314  1   150.65 ? 432 VAL D CG2 1 
HETATM 9010 C  C4  . UUS E 3 .   ? -10.189 -21.154 22.99   1   85.79  ? 301 UUS A C4  1 
HETATM 9011 C  C5  . UUS E 3 .   ? -9.061  -21.674 23.617  1   100.81 ? 301 UUS A C5  1 
HETATM 9012 C  C6  . UUS E 3 .   ? -7.8    -21.197 23.342  1   91.3   ? 301 UUS A C6  1 
HETATM 9013 N  N   . UUS E 3 .   ? -8.8    -19.643 21.785  1   78.84  ? 301 UUS A N   1 
HETATM 9014 C  C   . UUS E 3 .   ? -7.621  -20.146 22.395  1   86.9   ? 301 UUS A C   1 
HETATM 9015 O  O   . UUS E 3 .   ? -6.534  -19.659 22.087  1   92.96  ? 301 UUS A O   1 
HETATM 9016 C  C1  . UUS E 3 .   ? -8.631  -18.57  20.789  1   79.3   ? 301 UUS A C1  1 
HETATM 9017 C  C2  . UUS E 3 .   ? -8.481  -19.14  19.405  1   67.19  ? 301 UUS A C2  1 
HETATM 9018 C  C3  . UUS E 3 .   ? -10.035 -20.154 22.074  1   75.96  ? 301 UUS A C3  1 
HETATM 9019 O  O1  . UUS E 3 .   ? -9.671  -19.83  19.089  1   75.05  ? 301 UUS A O1  1 
HETATM 9020 BR BR  . UUS E 3 .   ? -9.209  -23.078 24.888  1   108.85 ? 301 UUS A BR  1 
HETATM 9021 C  C4  . UUS F 3 .   ? -17.647 15.577  3.167   1   82.79  ? 701 UUS B C4  1 
HETATM 9022 C  C5  . UUS F 3 .   ? -16.314 15.952  3.26    1   99.21  ? 701 UUS B C5  1 
HETATM 9023 C  C6  . UUS F 3 .   ? -15.957 17.095  3.957   1   107.62 ? 701 UUS B C6  1 
HETATM 9024 N  N   . UUS F 3 .   ? -18.308 17.494  4.414   1   90.33  ? 701 UUS B N   1 
HETATM 9025 C  C   . UUS F 3 .   ? -16.96  17.93   4.564   1   98.17  ? 701 UUS B C   1 
HETATM 9026 O  O   . UUS F 3 .   ? -16.732 18.976  5.204   1   85.88  ? 701 UUS B O   1 
HETATM 9027 C  C1  . UUS F 3 .   ? -19.37  18.316  5.038   1   82.24  ? 701 UUS B C1  1 
HETATM 9028 C  C2  . UUS F 3 .   ? -19.503 19.7    4.455   1   73.75  ? 701 UUS B C2  1 
HETATM 9029 C  C3  . UUS F 3 .   ? -18.613 16.356  3.72    1   81.6   ? 701 UUS B C3  1 
HETATM 9030 O  O1  . UUS F 3 .   ? -19.531 19.626  3.056   1   68.43  ? 701 UUS B O1  1 
HETATM 9031 BR BR  . UUS F 3 .   ? -14.953 14.927  2.393   1   82.07  ? 701 UUS B BR  1 
HETATM 9032 C  C4  . UUS G 3 .   ? -33.034 16.744  30.973  1   89.64  ? 501 UUS C C4  1 
HETATM 9033 C  C5  . UUS G 3 .   ? -32.712 15.866  29.943  1   96.85  ? 501 UUS C C5  1 
HETATM 9034 C  C6  . UUS G 3 .   ? -32.458 16.31   28.66   1   71.99  ? 501 UUS C C6  1 
HETATM 9035 N  N   . UUS G 3 .   ? -32.827 18.567  29.474  1   87.07  ? 501 UUS C N   1 
HETATM 9036 C  C   . UUS G 3 .   ? -32.494 17.709  28.389  1   74.68  ? 501 UUS C C   1 
HETATM 9037 O  O   . UUS G 3 .   ? -32.259 18.221  27.292  1   68.18  ? 501 UUS C O   1 
HETATM 9038 C  C1  . UUS G 3 .   ? -32.929 20.008  29.164  1   87.51  ? 501 UUS C C1  1 
HETATM 9039 C  C2  . UUS G 3 .   ? -32.111 20.934  30.016  1   99.42  ? 501 UUS C C2  1 
HETATM 9040 C  C3  . UUS G 3 .   ? -33.095 18.082  30.726  1   87.54  ? 501 UUS C C3  1 
HETATM 9041 O  O1  . UUS G 3 .   ? -31.518 21.919  29.215  1   107.98 ? 501 UUS C O1  1 
HETATM 9042 BR BR  . UUS G 3 .   ? -32.661 13.996  30.277  1   103.17 ? 501 UUS C BR  1 
HETATM 9043 C  C4  . UUS H 3 .   ? -18.459 13.06   31.469  1   119.13 ? 502 UUS C C4  1 
HETATM 9044 C  C5  . UUS H 3 .   ? -18.897 12.743  32.743  1   136.63 ? 502 UUS C C5  1 
HETATM 9045 C  C6  . UUS H 3 .   ? -18.197 11.864  33.548  1   134.56 ? 502 UUS C C6  1 
HETATM 9046 N  N   . UUS H 3 .   ? -16.568 11.661  31.774  1   131.85 ? 502 UUS C N   1 
HETATM 9047 C  C   . UUS H 3 .   ? -16.971 11.292  33.079  1   133.32 ? 502 UUS C C   1 
HETATM 9048 O  O   . UUS H 3 .   ? -16.251 10.516  33.716  1   125.87 ? 502 UUS C O   1 
HETATM 9049 C  C1  . UUS H 3 .   ? -15.305 11.08   31.279  1   126.51 ? 502 UUS C C1  1 
HETATM 9050 C  C2  . UUS H 3 .   ? -14.512 12.083  30.49   1   126.27 ? 502 UUS C C2  1 
HETATM 9051 C  C3  . UUS H 3 .   ? -17.309 12.511  31.003  1   123.13 ? 502 UUS C C3  1 
HETATM 9052 O  O1  . UUS H 3 .   ? -13.15  12.001  30.804  1   143.32 ? 502 UUS C O1  1 
HETATM 9053 BR BR  . UUS H 3 .   ? -20.539 13.454  33.373  1   178.41 ? 502 UUS C BR  1 
HETATM 9054 C  C4  . UUS I 3 .   ? -34.064 -23.671 46.524  1   83.72  ? 701 UUS D C4  1 
HETATM 9055 C  C5  . UUS I 3 .   ? -33.243 -23.807 45.419  1   86.05  ? 701 UUS D C5  1 
HETATM 9056 C  C6  . UUS I 3 .   ? -31.913 -24.167 45.539  1   87.23  ? 701 UUS D C6  1 
HETATM 9057 N  N   . UUS I 3 .   ? -32.245 -24.256 47.935  1   106.1  ? 701 UUS D N   1 
HETATM 9058 C  C   . UUS I 3 .   ? -31.347 -24.416 46.832  1   94.96  ? 701 UUS D C   1 
HETATM 9059 O  O   . UUS I 3 .   ? -30.165 -24.756 47.047  1   88.68  ? 701 UUS D O   1 
HETATM 9060 C  C1  . UUS I 3 .   ? -31.712 -24.437 49.304  1   105.6  ? 701 UUS D C1  1 
HETATM 9061 C  C2  . UUS I 3 .   ? -31.353 -23.1   49.921  1   92.56  ? 701 UUS D C2  1 
HETATM 9062 C  C3  . UUS I 3 .   ? -33.556 -23.896 47.758  1   97.49  ? 701 UUS D C3  1 
HETATM 9063 O  O1  . UUS I 3 .   ? -32.361 -22.107 49.686  1   76.56  ? 701 UUS D O1  1 
HETATM 9064 BR BR  . UUS I 3 .   ? -33.943 -23.449 43.692  1   85.8   ? 701 UUS D BR  1 
HETATM 9065 O  O   . HOH J 4 .   ? -19.579 -10.279 33.075  1   68.8   ? 401 HOH A O   1 
HETATM 9066 O  O   . HOH J 4 .   ? 4.469   -19.857 -5.33   1   58.92  ? 402 HOH A O   1 
HETATM 9067 O  O   . HOH J 4 .   ? -2.831  -21.08  16.49   1   70.85  ? 403 HOH A O   1 
HETATM 9068 O  O   . HOH J 4 .   ? -21.911 -17.802 31.673  1   45.34  ? 404 HOH A O   1 
HETATM 9069 O  O   . HOH J 4 .   ? -8.053  -16.75  -4.067  1   41.63  ? 405 HOH A O   1 
HETATM 9070 O  O   . HOH J 4 .   ? -15.085 -12.03  -5.182  1   47.5   ? 406 HOH A O   1 
HETATM 9071 O  O   . HOH J 4 .   ? -0.96   -25.032 -18.903 1   60.78  ? 407 HOH A O   1 
HETATM 9072 O  O   . HOH J 4 .   ? -13.184 -28.661 -5.152  1   37.82  ? 408 HOH A O   1 
HETATM 9073 O  O   . HOH J 4 .   ? -21.949 -18.798 27.735  1   57.67  ? 409 HOH A O   1 
HETATM 9074 O  O   . HOH J 4 .   ? 0.051   -33.531 8.284   1   43.18  ? 410 HOH A O   1 
HETATM 9075 O  O   . HOH J 4 .   ? 3.643   -21.021 -0.878  1   47.11  ? 411 HOH A O   1 
HETATM 9076 O  O   . HOH J 4 .   ? -21.845 -35.528 14.078  1   48.55  ? 412 HOH A O   1 
HETATM 9077 O  O   . HOH J 4 .   ? -12.352 -12.752 -9.13   1   47.32  ? 413 HOH A O   1 
HETATM 9078 O  O   . HOH J 4 .   ? -7.129  -13.054 8.232   1   42.68  ? 414 HOH A O   1 
HETATM 9079 O  O   . HOH J 4 .   ? -9.712  -47.03  -2.021  1   61     ? 415 HOH A O   1 
HETATM 9080 O  O   . HOH J 4 .   ? -22.751 -15.663 17.748  1   61.37  ? 416 HOH A O   1 
HETATM 9081 O  O   . HOH J 4 .   ? -2.9    -20.008 -5.455  1   38.82  ? 417 HOH A O   1 
HETATM 9082 O  O   . HOH J 4 .   ? -3.132  -13.064 6.17    1   52.46  ? 418 HOH A O   1 
HETATM 9083 O  O   . HOH J 4 .   ? 2.089   -15.615 -8.478  1   57.8   ? 419 HOH A O   1 
HETATM 9084 O  O   . HOH J 4 .   ? -9.745  -52.019 3.346   1   63.88  ? 420 HOH A O   1 
HETATM 9085 O  O   . HOH J 4 .   ? -5.035  -38.11  -4.449  1   55.03  ? 421 HOH A O   1 
HETATM 9086 O  O   . HOH J 4 .   ? 2.181   -29.72  13.021  1   59.95  ? 422 HOH A O   1 
HETATM 9087 O  O   . HOH J 4 .   ? -23.615 -42.696 15.596  1   57.08  ? 423 HOH A O   1 
HETATM 9088 O  O   . HOH J 4 .   ? -1.306  -17.931 -3.433  1   43.57  ? 424 HOH A O   1 
HETATM 9089 O  O   . HOH J 4 .   ? 1.266   -54.545 -0.998  1   53.94  ? 425 HOH A O   1 
HETATM 9090 O  O   . HOH J 4 .   ? -11.572 -16.865 -9.076  1   62.64  ? 426 HOH A O   1 
HETATM 9091 O  O   . HOH J 4 .   ? -7.608  -18.637 10.643  1   34.06  ? 427 HOH A O   1 
HETATM 9092 O  O   . HOH J 4 .   ? -16.37  -25.198 28.254  1   64.61  ? 428 HOH A O   1 
HETATM 9093 O  O   . HOH J 4 .   ? -3.85   -25.58  2.342   1   37.1   ? 429 HOH A O   1 
HETATM 9094 O  O   . HOH J 4 .   ? 1.048   -29.525 2.323   1   38.87  ? 430 HOH A O   1 
HETATM 9095 O  O   . HOH J 4 .   ? 1.632   -32.596 6.226   1   37.04  ? 431 HOH A O   1 
HETATM 9096 O  O   . HOH J 4 .   ? -19.68  -15.184 42.899  1   50.83  ? 432 HOH A O   1 
HETATM 9097 O  O   . HOH J 4 .   ? 1.034   -38.779 7.949   1   56.71  ? 433 HOH A O   1 
HETATM 9098 O  O   . HOH J 4 .   ? -19.171 -24.595 19.499  1   41.71  ? 434 HOH A O   1 
HETATM 9099 O  O   . HOH J 4 .   ? -23.04  -26.754 4.932   1   50.28  ? 435 HOH A O   1 
HETATM 9100 O  O   . HOH J 4 .   ? -8.508  -33.206 -13.215 1   50.54  ? 436 HOH A O   1 
HETATM 9101 O  O   . HOH J 4 .   ? -14.384 -27.181 -1.41   1   38.4   ? 437 HOH A O   1 
HETATM 9102 O  O   . HOH J 4 .   ? -19.623 -21.408 17.286  1   52.47  ? 438 HOH A O   1 
HETATM 9103 O  O   . HOH J 4 .   ? -4.628  -8.75   5.346   1   56.83  ? 439 HOH A O   1 
HETATM 9104 O  O   . HOH J 4 .   ? -5.38   -15.939 -4.307  1   52.51  ? 440 HOH A O   1 
HETATM 9105 O  O   . HOH J 4 .   ? -12.516 -10.963 5.411   1   42.8   ? 441 HOH A O   1 
HETATM 9106 O  O   . HOH J 4 .   ? -19.238 -31.323 23.471  1   53.56  ? 442 HOH A O   1 
HETATM 9107 O  O   . HOH J 4 .   ? -3.233  -5.746  7.646   1   59.51  ? 443 HOH A O   1 
HETATM 9108 O  O   . HOH J 4 .   ? -6.12   -24.414 6.017   1   50.56  ? 444 HOH A O   1 
HETATM 9109 O  O   . HOH J 4 .   ? -13.74  -36.197 -5.029  1   67.42  ? 445 HOH A O   1 
HETATM 9110 O  O   . HOH J 4 .   ? -12.667 -28.969 -2.376  1   49.8   ? 446 HOH A O   1 
HETATM 9111 O  O   . HOH J 4 .   ? -20.012 -28.881 22.292  1   53.7   ? 447 HOH A O   1 
HETATM 9112 O  O   . HOH J 4 .   ? -8.32   -10.518 -8.054  1   47.31  ? 448 HOH A O   1 
HETATM 9113 O  O   . HOH J 4 .   ? 5.092   -42.205 1.147   1   57.43  ? 449 HOH A O   1 
HETATM 9114 O  O   . HOH J 4 .   ? 10.038  -36.986 0.45    1   59.75  ? 450 HOH A O   1 
HETATM 9115 O  O   . HOH J 4 .   ? -12.9   -49.964 4.186   1   57.55  ? 451 HOH A O   1 
HETATM 9116 O  O   . HOH J 4 .   ? 10.807  -21.222 1.417   1   55.82  ? 452 HOH A O   1 
HETATM 9117 O  O   . HOH J 4 .   ? -2.774  -15.61  -3.582  1   42.33  ? 453 HOH A O   1 
HETATM 9118 O  O   . HOH J 4 .   ? 4.528   -21.889 7.769   1   54.01  ? 454 HOH A O   1 
HETATM 9119 O  O   . HOH J 4 .   ? -8.153  -23.753 -4.249  1   36.57  ? 455 HOH A O   1 
HETATM 9120 O  O   . HOH J 4 .   ? -3.602  -4.534  10.984  1   55.86  ? 456 HOH A O   1 
HETATM 9121 O  O   . HOH J 4 .   ? -17.303 -22.552 27.848  1   62.92  ? 457 HOH A O   1 
HETATM 9122 O  O   . HOH J 4 .   ? -10.58  -11.209 -10.159 1   44.76  ? 458 HOH A O   1 
HETATM 9123 O  O   . HOH J 4 .   ? -4.794  -19.465 -10.382 1   49.15  ? 459 HOH A O   1 
HETATM 9124 O  O   . HOH J 4 .   ? -22.108 -28.663 8.189   1   51.38  ? 460 HOH A O   1 
HETATM 9125 O  O   . HOH J 4 .   ? 13.337  -32.168 -2.074  1   55.91  ? 461 HOH A O   1 
HETATM 9126 O  O   . HOH J 4 .   ? 9.515   -22.268 -8.437  1   59.92  ? 462 HOH A O   1 
HETATM 9127 O  O   . HOH J 4 .   ? -23.516 -29.567 10.607  1   41.72  ? 463 HOH A O   1 
HETATM 9128 O  O   . HOH J 4 .   ? -18.632 -38.629 -1.242  1   48.61  ? 464 HOH A O   1 
HETATM 9129 O  O   . HOH J 4 .   ? -17.108 -32.946 -3.9    1   49     ? 465 HOH A O   1 
HETATM 9130 O  O   . HOH J 4 .   ? -16.178 -41.81  -2.989  1   50.56  ? 466 HOH A O   1 
HETATM 9131 O  O   . HOH J 4 .   ? -5.371  -42.794 -6.062  1   71.57  ? 467 HOH A O   1 
HETATM 9132 O  O   . HOH J 4 .   ? -18.714 -16.288 30.764  1   56.23  ? 468 HOH A O   1 
HETATM 9133 O  O   . HOH J 4 .   ? 3.952   -41.376 3.552   1   53.87  ? 469 HOH A O   1 
HETATM 9134 O  O   . HOH J 4 .   ? -18.102 -24.201 31.862  1   52.32  ? 470 HOH A O   1 
HETATM 9135 O  O   . HOH J 4 .   ? -15.808 -23.534 37.405  1   55.83  ? 471 HOH A O   1 
HETATM 9136 O  O   . HOH J 4 .   ? -6.504  -25.274 -11.232 1   48.73  ? 472 HOH A O   1 
HETATM 9137 O  O   . HOH J 4 .   ? 0.279   -37.532 -10.365 1   41.69  ? 473 HOH A O   1 
HETATM 9138 O  O   . HOH J 4 .   ? 13.554  -27.472 -10.155 1   60.23  ? 474 HOH A O   1 
HETATM 9139 O  O   . HOH J 4 .   ? -19.946 -32.82  18.584  1   63.5   ? 475 HOH A O   1 
HETATM 9140 O  O   . HOH J 4 .   ? -23.827 -43.289 7.936   1   72.5   ? 476 HOH A O   1 
HETATM 9141 O  O   . HOH J 4 .   ? 6.612   -19.658 3.061   1   56.58  ? 477 HOH A O   1 
HETATM 9142 O  O   . HOH J 4 .   ? 11.936  -22.499 -1.426  1   48.36  ? 478 HOH A O   1 
HETATM 9143 O  O   . HOH J 4 .   ? -22.796 -41.201 17.497  1   64.97  ? 479 HOH A O   1 
HETATM 9144 O  O   . HOH J 4 .   ? -3.096  -7.488  12.193  1   61.81  ? 480 HOH A O   1 
HETATM 9145 O  O   . HOH J 4 .   ? -15.961 -44.155 -2.15   1   62.91  ? 481 HOH A O   1 
HETATM 9146 O  O   . HOH J 4 .   ? -0.029  -11.437 -1.319  1   47.84  ? 482 HOH A O   1 
HETATM 9147 O  O   . HOH J 4 .   ? -22.818 -41.269 8.514   1   48.95  ? 483 HOH A O   1 
HETATM 9148 O  O   . HOH J 4 .   ? -2.718  -19.23  -11.897 1   50.16  ? 484 HOH A O   1 
HETATM 9149 O  O   . HOH J 4 .   ? -24.701 -27.383 10.274  1   54.91  ? 485 HOH A O   1 
HETATM 9150 O  O   . HOH J 4 .   ? -4.578  -36.212 -8.328  1   44.56  ? 486 HOH A O   1 
HETATM 9151 O  O   . HOH J 4 .   ? 5.031   -26.227 9.151   1   54.91  ? 487 HOH A O   1 
HETATM 9152 O  O   . HOH J 4 .   ? 12.501  -32.894 -15.823 1   55.88  ? 488 HOH A O   1 
HETATM 9153 O  O   . HOH J 4 .   ? -7.332  -51.714 6.565   1   64.33  ? 489 HOH A O   1 
HETATM 9154 O  O   . HOH J 4 .   ? -4.175  -26.541 24.473  1   66.77  ? 490 HOH A O   1 
HETATM 9155 O  O   . HOH J 4 .   ? 2.692   -24.984 13.981  1   55.87  ? 491 HOH A O   1 
HETATM 9156 O  O   . HOH J 4 .   ? 10.445  -41.609 -9.815  1   60.52  ? 492 HOH A O   1 
HETATM 9157 O  O   . HOH J 4 .   ? -19.921 -24.484 25.645  1   60.33  ? 493 HOH A O   1 
HETATM 9158 O  O   . HOH J 4 .   ? 15.842  -30.002 2.333   1   61.42  ? 494 HOH A O   1 
HETATM 9159 O  O   . HOH J 4 .   ? -2.316  -8.936  8.404   1   62.87  ? 495 HOH A O   1 
HETATM 9160 O  O   . HOH J 4 .   ? -20.158 -30.602 19.739  1   65.22  ? 496 HOH A O   1 
HETATM 9161 O  O   . HOH J 4 .   ? 13.299  -31.14  -18.102 1   64.91  ? 497 HOH A O   1 
HETATM 9162 O  O   . HOH J 4 .   ? 12.903  -35.491 7.622   1   59.22  ? 498 HOH A O   1 
HETATM 9163 O  O   . HOH J 4 .   ? -22.886 -38.791 18.187  1   58.31  ? 499 HOH A O   1 
HETATM 9164 O  O   . HOH J 4 .   ? -16.424 -10.436 -0.061  1   50.61  ? 500 HOH A O   1 
HETATM 9165 O  O   . HOH J 4 .   ? 3.378   -27.208 12.505  1   49.35  ? 501 HOH A O   1 
HETATM 9166 O  O   . HOH J 4 .   ? -24.321 -19.861 24.134  1   53.32  ? 502 HOH A O   1 
HETATM 9167 O  O   . HOH J 4 .   ? 11.47   -33.871 9.014   1   61.76  ? 503 HOH A O   1 
HETATM 9168 O  O   . HOH J 4 .   ? -24.272 -22.124 22.497  1   52.71  ? 504 HOH A O   1 
HETATM 9169 O  O   . HOH J 4 .   ? -1.061  -51.252 17.759  1   64.4   ? 505 HOH A O   1 
HETATM 9170 O  O   . HOH J 4 .   ? 13.727  -33.241 10.255  1   67.76  ? 506 HOH A O   1 
HETATM 9171 O  O   . HOH K 4 .   ? -30.465 16.438  7.621   1   58.12  ? 801 HOH B O   1 
HETATM 9172 O  O   . HOH K 4 .   ? -21.765 22.109  12.258  1   56.8   ? 802 HOH B O   1 
HETATM 9173 O  O   . HOH K 4 .   ? -29.166 9.601   -8.321  1   54.45  ? 803 HOH B O   1 
HETATM 9174 O  O   . HOH K 4 .   ? -17.252 19.95   2.049   1   67.46  ? 804 HOH B O   1 
HETATM 9175 O  O   . HOH K 4 .   ? -13.78  -10.956 -0.275  1   40.66  ? 805 HOH B O   1 
HETATM 9176 O  O   . HOH K 4 .   ? -24.182 -4.652  14.468  1   57.1   ? 806 HOH B O   1 
HETATM 9177 O  O   . HOH K 4 .   ? -8.752  2.019   16.954  1   50.76  ? 807 HOH B O   1 
HETATM 9178 O  O   . HOH K 4 .   ? -18.106 -0.896  -7.785  1   52.96  ? 808 HOH B O   1 
HETATM 9179 O  O   . HOH K 4 .   ? -17.048 -8.06   -4.017  1   50.85  ? 809 HOH B O   1 
HETATM 9180 O  O   . HOH K 4 .   ? -12.177 9.555   -9.858  1   52.68  ? 810 HOH B O   1 
HETATM 9181 O  O   . HOH K 4 .   ? -25.261 -5.026  3.674   1   61.21  ? 811 HOH B O   1 
HETATM 9182 O  O   . HOH K 4 .   ? -32.437 -10.13  0.943   1   48.36  ? 812 HOH B O   1 
HETATM 9183 O  O   . HOH K 4 .   ? -27     10.986  -12.03  1   56.4   ? 813 HOH B O   1 
HETATM 9184 O  O   . HOH K 4 .   ? -16.363 -8.351  1.609   1   28.62  ? 814 HOH B O   1 
HETATM 9185 O  O   . HOH K 4 .   ? -12.844 -10.287 2.87    1   46.35  ? 815 HOH B O   1 
HETATM 9186 O  O   . HOH K 4 .   ? -16.65  14.701  -8.293  1   46.37  ? 816 HOH B O   1 
HETATM 9187 O  O   . HOH K 4 .   ? -4.43   -4.564  -0.788  1   54.68  ? 817 HOH B O   1 
HETATM 9188 O  O   . HOH K 4 .   ? -23.718 20.135  0.682   1   65.3   ? 818 HOH B O   1 
HETATM 9189 O  O   . HOH K 4 .   ? -32.726 8.403   -10.107 1   58.97  ? 819 HOH B O   1 
HETATM 9190 O  O   . HOH K 4 .   ? -30.744 -18.314 -2.494  1   57.21  ? 820 HOH B O   1 
HETATM 9191 O  O   . HOH K 4 .   ? -21.062 8.394   -17.82  1   48.14  ? 821 HOH B O   1 
HETATM 9192 O  O   . HOH K 4 .   ? -17.617 -10.822 -5.047  1   50.44  ? 822 HOH B O   1 
HETATM 9193 O  O   . HOH K 4 .   ? -12.461 4.038   -5.87   1   52.82  ? 823 HOH B O   1 
HETATM 9194 O  O   . HOH K 4 .   ? -20.362 -13.205 -3.573  1   48.7   ? 824 HOH B O   1 
HETATM 9195 O  O   . HOH K 4 .   ? -5.783  -6.507  5.988   1   52.49  ? 825 HOH B O   1 
HETATM 9196 O  O   . HOH K 4 .   ? -32.761 -11.428 -22.831 1   68.36  ? 826 HOH B O   1 
HETATM 9197 O  O   . HOH K 4 .   ? -21.063 -1.729  -7.856  1   54.03  ? 827 HOH B O   1 
HETATM 9198 O  O   . HOH K 4 .   ? -27.42  12.716  -3.348  1   51.95  ? 828 HOH B O   1 
HETATM 9199 O  O   . HOH K 4 .   ? -36.97  -13.144 -3.932  1   57.35  ? 829 HOH B O   1 
HETATM 9200 O  O   . HOH K 4 .   ? -15.483 -27.531 1.093   1   35.67  ? 830 HOH B O   1 
HETATM 9201 O  O   . HOH K 4 .   ? -34.986 1.462   7.26    1   74.29  ? 831 HOH B O   1 
HETATM 9202 O  O   . HOH K 4 .   ? 3.92    -8.744  -2.362  1   65.5   ? 832 HOH B O   1 
HETATM 9203 O  O   . HOH K 4 .   ? -26.407 15.675  12.006  1   60.38  ? 833 HOH B O   1 
HETATM 9204 O  O   . HOH K 4 .   ? -16.222 16.57   7.942   1   53.7   ? 834 HOH B O   1 
HETATM 9205 O  O   . HOH K 4 .   ? -25.744 3.987   18.654  1   65.51  ? 835 HOH B O   1 
HETATM 9206 O  O   . HOH K 4 .   ? -26.261 10.956  -0.498  1   54.18  ? 836 HOH B O   1 
HETATM 9207 O  O   . HOH K 4 .   ? -24.661 9.49    -8.661  1   54.87  ? 837 HOH B O   1 
HETATM 9208 O  O   . HOH K 4 .   ? -30.021 11.735  -2.482  1   50.97  ? 838 HOH B O   1 
HETATM 9209 O  O   . HOH K 4 .   ? -19.337 21.008  12.337  1   55.6   ? 839 HOH B O   1 
HETATM 9210 O  O   . HOH K 4 .   ? -30.542 -11.864 -4.931  1   53.63  ? 840 HOH B O   1 
HETATM 9211 O  O   . HOH K 4 .   ? -19.772 -13.079 -0.729  1   43.3   ? 841 HOH B O   1 
HETATM 9212 O  O   . HOH K 4 .   ? -22.285 3.585   -26.422 1   75.8   ? 842 HOH B O   1 
HETATM 9213 O  O   . HOH K 4 .   ? -29.605 11.292  13.967  1   59.19  ? 843 HOH B O   1 
HETATM 9214 O  O   . HOH K 4 .   ? -6.287  -3.429  -3.928  1   43.92  ? 844 HOH B O   1 
HETATM 9215 O  O   . HOH K 4 .   ? -9.112  16.094  2.634   1   61.86  ? 845 HOH B O   1 
HETATM 9216 O  O   . HOH K 4 .   ? -15.266 -16.937 -13.121 1   54.01  ? 846 HOH B O   1 
HETATM 9217 O  O   . HOH K 4 .   ? -19.837 -9.452  10.592  1   48.28  ? 847 HOH B O   1 
HETATM 9218 O  O   . HOH K 4 .   ? -13.863 17.708  7.205   1   54.62  ? 848 HOH B O   1 
HETATM 9219 O  O   . HOH K 4 .   ? -26.224 20.541  2.041   1   59.19  ? 849 HOH B O   1 
HETATM 9220 O  O   . HOH K 4 .   ? -25.49  1.613   1.82    1   74.65  ? 850 HOH B O   1 
HETATM 9221 O  O   . HOH K 4 .   ? -28.794 -23.435 -0.623  1   67.91  ? 851 HOH B O   1 
HETATM 9222 O  O   . HOH K 4 .   ? -18.196 -13.214 -12.054 1   53.63  ? 852 HOH B O   1 
HETATM 9223 O  O   . HOH K 4 .   ? -19.261 10.186  -8.482  1   47.37  ? 853 HOH B O   1 
HETATM 9224 O  O   . HOH K 4 .   ? -18.521 -8.847  3.565   1   43.97  ? 854 HOH B O   1 
HETATM 9225 O  O   . HOH K 4 .   ? -24.403 -24.423 -4.225  1   50.47  ? 855 HOH B O   1 
HETATM 9226 O  O   . HOH K 4 .   ? -22.985 -2.065  -1.666  1   42.43  ? 856 HOH B O   1 
HETATM 9227 O  O   . HOH K 4 .   ? -25.028 -24.398 -1.443  1   52.94  ? 857 HOH B O   1 
HETATM 9228 O  O   . HOH K 4 .   ? -27.908 -3.813  3.271   1   66.36  ? 858 HOH B O   1 
HETATM 9229 O  O   . HOH K 4 .   ? -37.651 -7.139  -6.352  1   53.44  ? 859 HOH B O   1 
HETATM 9230 O  O   . HOH K 4 .   ? -29.189 17.138  0.619   1   61.39  ? 860 HOH B O   1 
HETATM 9231 O  O   . HOH K 4 .   ? -31.049 -19.7   -5.09   1   71.86  ? 861 HOH B O   1 
HETATM 9232 O  O   . HOH K 4 .   ? -35.467 -8.546  -1.509  1   39.93  ? 862 HOH B O   1 
HETATM 9233 O  O   . HOH K 4 .   ? -22.016 10.823  -8.592  1   46.47  ? 863 HOH B O   1 
HETATM 9234 O  O   . HOH K 4 .   ? -12.682 -22.488 -10.829 1   60.57  ? 864 HOH B O   1 
HETATM 9235 O  O   . HOH K 4 .   ? -17.802 -13.758 -15.052 1   57.27  ? 865 HOH B O   1 
HETATM 9236 O  O   . HOH K 4 .   ? -21.977 11.174  -11.978 1   54.33  ? 866 HOH B O   1 
HETATM 9237 O  O   . HOH K 4 .   ? -25.98  -26.288 4.015   1   50.31  ? 867 HOH B O   1 
HETATM 9238 O  O   . HOH K 4 .   ? -33.071 -16.578 -3.292  1   37.22  ? 868 HOH B O   1 
HETATM 9239 O  O   . HOH K 4 .   ? -32.596 17.134  8.752   1   68.56  ? 869 HOH B O   1 
HETATM 9240 O  O   . HOH K 4 .   ? -20.443 -2.669  21.152  1   53.74  ? 870 HOH B O   1 
HETATM 9241 O  O   . HOH K 4 .   ? -7.76   18.247  14.557  1   60.52  ? 871 HOH B O   1 
HETATM 9242 O  O   . HOH K 4 .   ? -23.791 8.664   -18.267 1   60.55  ? 872 HOH B O   1 
HETATM 9243 O  O   . HOH K 4 .   ? -29.853 9.079   12.835  1   52.87  ? 873 HOH B O   1 
HETATM 9244 O  O   . HOH K 4 .   ? -31.727 -17.83  -18.402 1   58.1   ? 874 HOH B O   1 
HETATM 9245 O  O   . HOH K 4 .   ? -13.282 -5.257  -5.603  1   45.38  ? 875 HOH B O   1 
HETATM 9246 O  O   . HOH K 4 .   ? -38.216 -10.997 -15.544 1   52.74  ? 876 HOH B O   1 
HETATM 9247 O  O   . HOH K 4 .   ? -29.74  -12.69  -20.872 1   60.91  ? 877 HOH B O   1 
HETATM 9248 O  O   . HOH K 4 .   ? -28.722 15.634  17.657  1   60.59  ? 878 HOH B O   1 
HETATM 9249 O  O   . HOH K 4 .   ? 0.368   11.555  8.147   1   53.09  ? 879 HOH B O   1 
HETATM 9250 O  O   . HOH K 4 .   ? -33.178 7.786   1.477   1   60.76  ? 880 HOH B O   1 
HETATM 9251 O  O   . HOH K 4 .   ? -37.134 -2.418  -7.143  1   50.29  ? 881 HOH B O   1 
HETATM 9252 O  O   . HOH K 4 .   ? -30.896 15.927  2.648   1   55.8   ? 882 HOH B O   1 
HETATM 9253 O  O   . HOH K 4 .   ? -11.34  18.255  14.594  1   48.2   ? 883 HOH B O   1 
HETATM 9254 O  O   . HOH K 4 .   ? -21.823 -1.292  -26.659 1   68.11  ? 884 HOH B O   1 
HETATM 9255 O  O   . HOH K 4 .   ? -35.222 -3.608  -1.793  1   56.75  ? 885 HOH B O   1 
HETATM 9256 O  O   . HOH K 4 .   ? -30.487 -1.492  -26.117 1   66.03  ? 886 HOH B O   1 
HETATM 9257 O  O   . HOH K 4 .   ? -23.158 -0.714  0.721   1   64.09  ? 887 HOH B O   1 
HETATM 9258 O  O   . HOH K 4 .   ? -13.338 19.066  13.268  1   46.3   ? 888 HOH B O   1 
HETATM 9259 O  O   . HOH K 4 .   ? -26.232 16.391  -8.266  1   53.61  ? 889 HOH B O   1 
HETATM 9260 O  O   . HOH K 4 .   ? -9.831  -7.307  -8.429  1   72.65  ? 890 HOH B O   1 
HETATM 9261 O  O   . HOH K 4 .   ? -40.693 -15.046 -8.762  1   68.08  ? 891 HOH B O   1 
HETATM 9262 O  O   . HOH K 4 .   ? -6.234  -6.471  -2.139  1   46.43  ? 892 HOH B O   1 
HETATM 9263 O  O   . HOH K 4 .   ? -26.618 -1.676  11.83   1   59.93  ? 893 HOH B O   1 
HETATM 9264 O  O   . HOH K 4 .   ? -24.518 -20.41  -13.825 1   71.87  ? 894 HOH B O   1 
HETATM 9265 O  O   . HOH K 4 .   ? -30.22  -21.101 -12.082 1   49.6   ? 895 HOH B O   1 
HETATM 9266 O  O   . HOH K 4 .   ? -31.825 3.455   -26.914 1   71.56  ? 896 HOH B O   1 
HETATM 9267 O  O   . HOH K 4 .   ? -23.097 -28.496 -7.254  1   54.55  ? 897 HOH B O   1 
HETATM 9268 O  O   . HOH K 4 .   ? -19.713 -5.712  -26.695 1   59.2   ? 898 HOH B O   1 
HETATM 9269 O  O   . HOH K 4 .   ? -27.582 -13.194 -19.414 1   49.46  ? 899 HOH B O   1 
HETATM 9270 O  O   . HOH K 4 .   ? -27.488 2.265   -0.762  1   63.66  ? 900 HOH B O   1 
HETATM 9271 O  O   . HOH K 4 .   ? -33.93  -12.751 2.935   1   50.61  ? 901 HOH B O   1 
HETATM 9272 O  O   . HOH K 4 .   ? -31.292 16.265  5.405   1   68.91  ? 902 HOH B O   1 
HETATM 9273 O  O   . HOH K 4 .   ? -18.877 -7.4    19.692  1   50.49  ? 903 HOH B O   1 
HETATM 9274 O  O   . HOH K 4 .   ? -28.996 11.47   -10.483 1   49.81  ? 904 HOH B O   1 
HETATM 9275 O  O   . HOH K 4 .   ? -18.774 -15.791 -16.393 1   52.41  ? 905 HOH B O   1 
HETATM 9276 O  O   . HOH K 4 .   ? -35.23  -9.706  1.103   1   49.49  ? 906 HOH B O   1 
HETATM 9277 O  O   . HOH K 4 .   ? -37.907 -9.862  -2.161  1   55.63  ? 907 HOH B O   1 
HETATM 9278 O  O   . HOH K 4 .   ? -24.358 10.011  -11.236 1   48.09  ? 908 HOH B O   1 
HETATM 9279 O  O   . HOH K 4 .   ? -14.73  18.291  1.59    1   64.17  ? 909 HOH B O   1 
HETATM 9280 O  O   . HOH K 4 .   ? -16.231 -11.615 -10.633 1   45.97  ? 910 HOH B O   1 
HETATM 9281 O  O   . HOH K 4 .   ? -36.722 -5.986  -1.723  1   50.78  ? 911 HOH B O   1 
HETATM 9282 O  O   . HOH K 4 .   ? -25.339 -0.167  -1.051  1   55.81  ? 912 HOH B O   1 
HETATM 9283 O  O   . HOH K 4 .   ? -36.66  -7.76   2.782   1   59.09  ? 913 HOH B O   1 
HETATM 9284 O  O   . HOH L 4 .   ? -28.744 13.727  19.39   1   67.45  ? 601 HOH C O   1 
HETATM 9285 O  O   . HOH L 4 .   ? -23.037 10.662  21.657  1   51.73  ? 602 HOH C O   1 
HETATM 9286 O  O   . HOH L 4 .   ? -59     10.297  29.438  1   65.27  ? 603 HOH C O   1 
HETATM 9287 O  O   . HOH L 4 .   ? -54.548 19.25   39.707  1   57.54  ? 604 HOH C O   1 
HETATM 9288 O  O   . HOH L 4 .   ? -28.633 15.702  21.08   1   57.41  ? 605 HOH C O   1 
HETATM 9289 O  O   . HOH L 4 .   ? -41.822 37.563  29.217  1   63.16  ? 606 HOH C O   1 
HETATM 9290 O  O   . HOH L 4 .   ? -45.434 -2.442  35.559  1   54.03  ? 607 HOH C O   1 
HETATM 9291 O  O   . HOH L 4 .   ? -27.583 10.162  17.976  1   44.08  ? 608 HOH C O   1 
HETATM 9292 O  O   . HOH L 4 .   ? -23.055 10.867  18.104  1   54.31  ? 609 HOH C O   1 
HETATM 9293 O  O   . HOH L 4 .   ? -24.274 0.076   48.494  1   54.68  ? 610 HOH C O   1 
HETATM 9294 O  O   . HOH L 4 .   ? -43.982 7.288   43.905  1   60.63  ? 611 HOH C O   1 
HETATM 9295 O  O   . HOH L 4 .   ? -51.245 24.073  35.785  1   53.45  ? 612 HOH C O   1 
HETATM 9296 O  O   . HOH L 4 .   ? -57.51  7.897   27.939  1   62.04  ? 613 HOH C O   1 
HETATM 9297 O  O   . HOH L 4 .   ? -13.911 5.746   21.076  1   57.79  ? 614 HOH C O   1 
HETATM 9298 O  O   . HOH L 4 .   ? -54.254 2.05    38.85   1   54.53  ? 615 HOH C O   1 
HETATM 9299 O  O   . HOH L 4 .   ? -42.222 1.244   42.927  1   57.07  ? 616 HOH C O   1 
HETATM 9300 O  O   . HOH L 4 .   ? -57.912 7.565   36.034  1   58.57  ? 617 HOH C O   1 
HETATM 9301 O  O   . HOH L 4 .   ? -54.384 23.514  53.514  1   63.35  ? 618 HOH C O   1 
HETATM 9302 O  O   . HOH L 4 .   ? -55.172 9.249   26.566  1   53.58  ? 619 HOH C O   1 
HETATM 9303 O  O   . HOH L 4 .   ? -37.085 16.724  34.87   1   59.56  ? 620 HOH C O   1 
HETATM 9304 O  O   . HOH L 4 .   ? -35.73  12.372  30.731  1   61.56  ? 621 HOH C O   1 
HETATM 9305 O  O   . HOH L 4 .   ? -38.283 8.529   21.598  1   55.49  ? 622 HOH C O   1 
HETATM 9306 O  O   . HOH L 4 .   ? -40.853 34.863  34.994  1   62.86  ? 623 HOH C O   1 
HETATM 9307 O  O   . HOH L 4 .   ? -35.228 0.504   44.036  1   49.43  ? 624 HOH C O   1 
HETATM 9308 O  O   . HOH L 4 .   ? -27.542 1.237   24.42   1   77.13  ? 625 HOH C O   1 
HETATM 9309 O  O   . HOH L 4 .   ? -49.14  13.029  34.728  1   61.54  ? 626 HOH C O   1 
HETATM 9310 O  O   . HOH L 4 .   ? -37.5   12.086  19.863  1   58.61  ? 627 HOH C O   1 
HETATM 9311 O  O   . HOH L 4 .   ? -52.229 23.268  38.081  1   50.96  ? 628 HOH C O   1 
HETATM 9312 O  O   . HOH L 4 .   ? -42.468 9.393   34.876  1   49.58  ? 629 HOH C O   1 
HETATM 9313 O  O   . HOH L 4 .   ? -43.601 -0.764  35.047  1   47.84  ? 630 HOH C O   1 
HETATM 9314 O  O   . HOH L 4 .   ? -23.377 3.982   21.229  1   55.19  ? 631 HOH C O   1 
HETATM 9315 O  O   . HOH L 4 .   ? -29.633 17.808  20.233  1   62.78  ? 632 HOH C O   1 
HETATM 9316 O  O   . HOH L 4 .   ? -19.395 12.107  36.623  1   69.64  ? 633 HOH C O   1 
HETATM 9317 O  O   . HOH L 4 .   ? -39.149 9.213   16.728  1   61.87  ? 634 HOH C O   1 
HETATM 9318 O  O   . HOH L 4 .   ? -21.525 0.043   28.799  1   57.95  ? 635 HOH C O   1 
HETATM 9319 O  O   . HOH L 4 .   ? -15.194 15.664  30.719  1   63.57  ? 636 HOH C O   1 
HETATM 9320 O  O   . HOH L 4 .   ? -62.589 -4.297  41.936  1   54.89  ? 637 HOH C O   1 
HETATM 9321 O  O   . HOH L 4 .   ? -26.161 2.524   22.102  1   77.49  ? 638 HOH C O   1 
HETATM 9322 O  O   . HOH L 4 .   ? -43.111 33.423  35.78   1   65.85  ? 639 HOH C O   1 
HETATM 9323 O  O   . HOH L 4 .   ? -34.779 14.119  33.5    1   76.53  ? 640 HOH C O   1 
HETATM 9324 O  O   . HOH L 4 .   ? -22.782 1.031   25.519  1   73.24  ? 641 HOH C O   1 
HETATM 9325 O  O   . HOH L 4 .   ? -32.462 22.681  21.208  1   70.63  ? 642 HOH C O   1 
HETATM 9326 O  O   . HOH L 4 .   ? -26.021 17.546  18.476  1   69.74  ? 643 HOH C O   1 
HETATM 9327 O  O   . HOH L 4 .   ? -25.913 8.501   19.579  1   53.65  ? 644 HOH C O   1 
HETATM 9328 O  O   . HOH L 4 .   ? -33.901 21.291  32.05   1   71.08  ? 645 HOH C O   1 
HETATM 9329 O  O   . HOH L 4 .   ? -40.918 4.895   40.702  1   52.04  ? 646 HOH C O   1 
HETATM 9330 O  O   . HOH L 4 .   ? -16.321 7.136   34.196  1   65.3   ? 647 HOH C O   1 
HETATM 9331 O  O   . HOH L 4 .   ? -34.394 -1.037  21.565  1   71.33  ? 648 HOH C O   1 
HETATM 9332 O  O   . HOH L 4 .   ? -24.364 8.595   22.079  1   64.58  ? 649 HOH C O   1 
HETATM 9333 O  O   . HOH L 4 .   ? -23.043 1.596   21.447  1   58.17  ? 650 HOH C O   1 
HETATM 9334 O  O   . HOH L 4 .   ? -31.591 12.701  18.842  1   54.48  ? 651 HOH C O   1 
HETATM 9335 O  O   . HOH M 4 .   ? -19.66  -12.276 48.037  1   66     ? 801 HOH D O   1 
HETATM 9336 O  O   . HOH M 4 .   ? -49.446 -16.124 17.724  1   52.31  ? 802 HOH D O   1 
HETATM 9337 O  O   . HOH M 4 .   ? -28.927 -29.886 29.596  1   53.21  ? 803 HOH D O   1 
HETATM 9338 O  O   . HOH M 4 .   ? -38.553 -26.859 33.197  1   54.06  ? 804 HOH D O   1 
HETATM 9339 O  O   . HOH M 4 .   ? -36.059 -4.179  46.367  1   54.16  ? 805 HOH D O   1 
HETATM 9340 O  O   . HOH M 4 .   ? -45.722 -6.295  33.532  1   44.61  ? 806 HOH D O   1 
HETATM 9341 O  O   . HOH M 4 .   ? -31.826 -5.29   51.759  1   70.95  ? 807 HOH D O   1 
HETATM 9342 O  O   . HOH M 4 .   ? -27.082 -4.606  40.917  1   55.42  ? 808 HOH D O   1 
HETATM 9343 O  O   . HOH M 4 .   ? -47.959 -7.913  45.902  1   45.72  ? 809 HOH D O   1 
HETATM 9344 O  O   . HOH M 4 .   ? -60.021 5.183   36.802  1   70.01  ? 810 HOH D O   1 
HETATM 9345 O  O   . HOH M 4 .   ? -50.242 -5.2    29.359  1   58.48  ? 811 HOH D O   1 
HETATM 9346 O  O   . HOH M 4 .   ? -22.256 -7.682  37.538  1   58.39  ? 812 HOH D O   1 
HETATM 9347 O  O   . HOH M 4 .   ? -38.766 -3.59   28.13   1   47.8   ? 813 HOH D O   1 
HETATM 9348 O  O   . HOH M 4 .   ? -56.127 0.964   20.203  1   67.78  ? 814 HOH D O   1 
HETATM 9349 O  O   . HOH M 4 .   ? -46.447 -17.353 43.725  1   56.6   ? 815 HOH D O   1 
HETATM 9350 O  O   . HOH M 4 .   ? -25.178 -25.282 31.774  1   50.18  ? 816 HOH D O   1 
HETATM 9351 O  O   . HOH M 4 .   ? -40.7   -1.247  42.548  1   49.02  ? 817 HOH D O   1 
HETATM 9352 O  O   . HOH M 4 .   ? -53.478 -12.956 21.561  1   63.87  ? 818 HOH D O   1 
HETATM 9353 O  O   . HOH M 4 .   ? -46.109 -15.662 31.312  1   58.26  ? 819 HOH D O   1 
HETATM 9354 O  O   . HOH M 4 .   ? -28.655 -23.407 44.908  1   49.45  ? 820 HOH D O   1 
HETATM 9355 O  O   . HOH M 4 .   ? -51.263 -11.923 42.447  1   62.27  ? 821 HOH D O   1 
HETATM 9356 O  O   . HOH M 4 .   ? -46.202 -4.537  46.192  1   66.01  ? 822 HOH D O   1 
HETATM 9357 O  O   . HOH M 4 .   ? -38.225 -26.478 44.43   1   56.24  ? 823 HOH D O   1 
HETATM 9358 O  O   . HOH M 4 .   ? -28.658 -23.349 42.34   1   41.17  ? 824 HOH D O   1 
HETATM 9359 O  O   . HOH M 4 .   ? -44.267 -6.182  31.105  1   49.25  ? 825 HOH D O   1 
HETATM 9360 O  O   . HOH M 4 .   ? -20.521 -23.723 27.825  1   55.91  ? 826 HOH D O   1 
HETATM 9361 O  O   . HOH M 4 .   ? -43.146 -34.156 37.346  1   67.96  ? 827 HOH D O   1 
HETATM 9362 O  O   . HOH M 4 .   ? -33.384 -11.054 25.743  1   55     ? 828 HOH D O   1 
HETATM 9363 O  O   . HOH M 4 .   ? -33.339 -31.318 30.095  1   77.03  ? 829 HOH D O   1 
HETATM 9364 O  O   . HOH M 4 .   ? -42.392 -22.602 30.404  1   73.53  ? 830 HOH D O   1 
HETATM 9365 O  O   . HOH M 4 .   ? -35.023 -33.01  32.976  1   61.63  ? 831 HOH D O   1 
HETATM 9366 O  O   . HOH M 4 .   ? -38.896 -27.24  24.536  1   75.9   ? 832 HOH D O   1 
HETATM 9367 O  O   . HOH M 4 .   ? -47.942 -4.248  43.591  1   46.6   ? 833 HOH D O   1 
HETATM 9368 O  O   . HOH M 4 .   ? -50.77  -9.909  39.277  1   53.87  ? 834 HOH D O   1 
HETATM 9369 O  O   . HOH M 4 .   ? -30.99  -30.952 29.02   1   72.28  ? 835 HOH D O   1 
HETATM 9370 O  O   . HOH M 4 .   ? -27.473 -21.615 25.997  1   60.13  ? 836 HOH D O   1 
HETATM 9371 O  O   . HOH M 4 .   ? -25.171 -13.261 26.012  1   66.18  ? 837 HOH D O   1 
HETATM 9372 O  O   . HOH M 4 .   ? -58.926 5.371   27.172  1   60.48  ? 838 HOH D O   1 
HETATM 9373 O  O   . HOH M 4 .   ? -39.257 -32.237 35.826  1   55.56  ? 839 HOH D O   1 
HETATM 9374 O  O   . HOH M 4 .   ? -44.696 -18.163 29.629  1   52.83  ? 840 HOH D O   1 
# 
