data_9EQ2
# 
_entry.id   9EQ2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EQ2         pdb_00009eq2 10.2210/pdb9eq2/pdb 
WWPDB D_1292137221 ?            ?                   
EMDB  EMD-19894    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-01-29 ? 
2  'EM metadata'     1 0 2025-01-29 ? 
3  'Additional map'  1 0 2025-01-29 1 
4  'Additional map'  1 0 2025-01-29 2 
5  'Additional map'  1 0 2025-01-29 3 
6  FSC               1 0 2025-01-29 ? 
7  'Half map'        1 0 2025-01-29 1 
8  'Half map'        1 0 2025-01-29 2 
9  Image             1 0 2025-01-29 ? 
10 'Primary map'     1 0 2025-01-29 ? 
11 'Structure model' 1 1 2025-03-12 ? 
12 'EM metadata'     1 1 2025-03-12 ? 
13 'Structure model' 1 2 2025-04-16 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  'Additional map'  repository 'Initial release' ? ? 
4  4  'Additional map'  repository 'Initial release' ? ? 
5  5  'Additional map'  repository 'Initial release' ? ? 
6  6  FSC               repository 'Initial release' ? ? 
7  7  'Half map'        repository 'Initial release' ? ? 
8  8  'Half map'        repository 'Initial release' ? ? 
9  9  Image             repository 'Initial release' ? ? 
10 10 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 11 'Structure model' 'Data collection'      
2 11 'Structure model' 'Database references'  
3 12 'EM metadata'     'Database references'  
4 12 'EM metadata'     'Experimental summary' 
5 13 'Structure model' 'Data collection'      
6 13 'Structure model' 'Database references'  
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 11 'Structure model' citation        
2 11 'Structure model' citation_author 
3 11 'Structure model' em_admin        
4 12 'EM metadata'     citation        
5 12 'EM metadata'     citation_author 
6 12 'EM metadata'     em_admin        
7 13 'Structure model' citation        
8 13 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  11 'Structure model' '_citation.country'                 
2  11 'Structure model' '_citation.journal_abbrev'          
3  11 'Structure model' '_citation.journal_id_ASTM'         
4  11 'Structure model' '_citation.journal_id_CSD'          
5  11 'Structure model' '_citation.journal_id_ISSN'         
6  11 'Structure model' '_citation.pdbx_database_id_DOI'    
7  11 'Structure model' '_citation.pdbx_database_id_PubMed' 
8  11 'Structure model' '_citation.title'                   
9  11 'Structure model' '_citation.year'                    
10 11 'Structure model' '_citation_author.identifier_ORCID' 
11 11 'Structure model' '_citation_author.name'             
12 11 'Structure model' '_em_admin.last_update'             
13 12 'EM metadata'     '_citation.country'                 
14 12 'EM metadata'     '_citation.journal_abbrev'          
15 12 'EM metadata'     '_citation.journal_id_ASTM'         
16 12 'EM metadata'     '_citation.journal_id_CSD'          
17 12 'EM metadata'     '_citation.journal_id_ISSN'         
18 12 'EM metadata'     '_citation.pdbx_database_id_DOI'    
19 12 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
20 12 'EM metadata'     '_citation.title'                   
21 12 'EM metadata'     '_citation.year'                    
22 12 'EM metadata'     '_citation_author.identifier_ORCID' 
23 12 'EM metadata'     '_citation_author.name'             
24 12 'EM metadata'     '_em_admin.last_update'             
25 13 'Structure model' '_citation.journal_volume'          
26 13 'Structure model' '_citation.page_first'              
27 13 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EQ2 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Arabidopsis thaliana R2T complex' 
_pdbx_database_related.db_id          EMD-19894 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ollorca@cnio.es 
_pdbx_contact_author.name_first         Oscar 
_pdbx_contact_author.name_last          Llorca 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7872-3442 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lopez-Perrote, A.' 1 0000-0001-7872-3442 
'Llorca, O.'        2 0000-0001-5705-0699 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Structure 
_citation.journal_id_ASTM           STRUE6 
_citation.journal_id_CSD            2005 
_citation.journal_id_ISSN           0969-2126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            33 
_citation.language                  ? 
_citation.page_first                740 
_citation.page_last                 ? 
_citation.title                     
'The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.str.2025.01.023 
_citation.pdbx_database_id_PubMed   40015274 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Palacios-Abella, A.' 1 ? 
primary 'Lopez-Perrote, A.'   2 ? 
primary 'Boskovic, J.'        3 ? 
primary 'Fonseca, S.'         4 ? 
primary 'Urbez, C.'           5 ? 
primary 'Rubio, V.'           6 ? 
primary 'Llorca, O.'          7 ? 
primary 'Alabadi, D.'         8 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'RuvB-like protein 1'      53750.754 3 3.6.4.12 ? ? 
;Protein sequence contains a N-terminal 10xHistidine tag and TEV protease cleavage site that do not affect protein activity nor structure
;
2 polymer     man 'RuvB-like helicase'       54007.848 3 3.6.4.12 ? ? 
;Protein sequence contains a stretch of 18 residues extra at the N-terminus due to cloning design that does not affect protein activity nor structure
;
3 polymer     man At1g56440                  59144.980 1 ?        ? ? 
;Protein sequence contains a N-terminal His-tag followed by an IF2D1 tag and a TEV protease site, and C-terminal Strep-II tag with HRV 3C protease site that do not affect protein activity nor structure
;
4 non-polymer syn "ADENOSINE-5'-DIPHOSPHATE" 427.201   3 ?        ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 '49 kDa TATA box-binding protein-interacting protein homolog,AtTIP49a,Ruv DNA-helicase-like protein' 
3 'Tetratricopeptide repeat (TPR)-like superfamily protein'                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGSSHHHHHHHHSSGENLYFQGSHMLEDPMEKVKIEEIQSTAKKQRIATHTHIKGLGLEPTGIPIKLAAGFVGQLEAREA
AGLVVDMIKQKKMAGKALLLAGPPGTGKTALALGISQELGSKVPFCPMVGSEVYSSEVKKTEVLMENFRRAIGLRIKETK
EVYEGEVTELSPEETESLTGGYGKSISHVVITLKTVKGTKHLKLDPTIYDALIKEKVAVGDVIYIEANSGAVKRVGRSDA
FATEFDLEAEEYVPLPKGEVHKKKEIVQDVTLQDLDAANARPQGGQDILSLMGQMMKPRKTEITDKLRQEINKVVNRYID
EGVAELVPGVLFIDEVHMLDMECFSYLNRALESSLSPIVIFATNRGVCNVRGTDMPSPHGVPIDLLDRLVIIRTQIYDPS
EMIQIIAIRAQVEELTVDEECLVLLGEIGQRTSLRHAVQLLSPASIVAKMNGRDNICKADIEEVTSLYLDAKSSAKLLHE
QQEKYIS
;
;MGSSHHHHHHHHSSGENLYFQGSHMLEDPMEKVKIEEIQSTAKKQRIATHTHIKGLGLEPTGIPIKLAAGFVGQLEAREA
AGLVVDMIKQKKMAGKALLLAGPPGTGKTALALGISQELGSKVPFCPMVGSEVYSSEVKKTEVLMENFRRAIGLRIKETK
EVYEGEVTELSPEETESLTGGYGKSISHVVITLKTVKGTKHLKLDPTIYDALIKEKVAVGDVIYIEANSGAVKRVGRSDA
FATEFDLEAEEYVPLPKGEVHKKKEIVQDVTLQDLDAANARPQGGQDILSLMGQMMKPRKTEITDKLRQEINKVVNRYID
EGVAELVPGVLFIDEVHMLDMECFSYLNRALESSLSPIVIFATNRGVCNVRGTDMPSPHGVPIDLLDRLVIIRTQIYDPS
EMIQIIAIRAQVEELTVDEECLVLLGEIGQRTSLRHAVQLLSPASIVAKMNGRDNICKADIEEVTSLYLDAKSSAKLLHE
QQEKYIS
;
A,C,B ? 
2 'polypeptide(L)' no no 
;MADLNWISAGHAIADVGTMAELKLSESRDLTRVERIGAHSHIRGLGLDSALEPRAVSEGMVGQVKARKAAGVILQMIREG
KIAGRAILIAGQPGTGKTAIAMGMAKSLGLETPFAMIAGSEIFSLEMSKTEALTQSFRKAIGVRIKEETEVIEGEVVEVQ
IDRPASSGVASKSGKMTMKTTDMETVYDMGAKMIEALNKEKVQSGDVIAIDKATGKITKLGRSFSRSRDYDAMGAQTKFV
QCPEGELQKRKEVVHCVTLHEIDVINSRTQGFLALFTGDTGEIRSEVREQIDTKVAEWREEGKAEIVPGVLFIDEVHMLD
IECFSFLNRALENEMSPILVVATNRGVTTIRGTNQKSPHGIPIDLLDRLLIITTQPYTDDDIRKILEIRCQEEDVEMNEE
AKQLLTLIGRDTSLRYAIHLITAAALSCQKRKGKVVEVEDIQRVYRLFLDVRRSMQYLVEYQSQYMFSEPIKNDEAAAED
EQDAMQI
;
;MADLNWISAGHAIADVGTMAELKLSESRDLTRVERIGAHSHIRGLGLDSALEPRAVSEGMVGQVKARKAAGVILQMIREG
KIAGRAILIAGQPGTGKTAIAMGMAKSLGLETPFAMIAGSEIFSLEMSKTEALTQSFRKAIGVRIKEETEVIEGEVVEVQ
IDRPASSGVASKSGKMTMKTTDMETVYDMGAKMIEALNKEKVQSGDVIAIDKATGKITKLGRSFSRSRDYDAMGAQTKFV
QCPEGELQKRKEVVHCVTLHEIDVINSRTQGFLALFTGDTGEIRSEVREQIDTKVAEWREEGKAEIVPGVLFIDEVHMLD
IECFSFLNRALENEMSPILVVATNRGVTTIRGTNQKSPHGIPIDLLDRLLIITTQPYTDDDIRKILEIRCQEEDVEMNEE
AKQLLTLIGRDTSLRYAIHLITAAALSCQKRKGKVVEVEDIQRVYRLFLDVRRSMQYLVEYQSQYMFSEPIKNDEAAAED
EQDAMQI
;
D,F,E ? 
3 'polypeptide(L)' no no 
;MGSSHHHHHHHHHHMTDVTIKGGENLYFQGMARSPSKHGRDQTQDFQGFFNDLQDWELSLKDKDKKIKQQPANSSNPSSE
TFRPSGSGKYDFAKKYRSIRDLSSSLIGESLLDSSSEKEQGNEFFKQKKFNEAIDCYSRSIALSPNAVTYANRAMAYLKI
KRYREAEVDCTEALNLDDRYIKAYSRRATARKELGMIKEAKEDAEFALRLEPESQELKKQYADIKSLLEKEIIEKATGAM
QSTAQELLKTSGLDKKIQKPKTEMTSKPVTLVAKTNRDIVQPVLGSNESSGKKLIENIQPEEKSKEGSMKIPAITEILDS
KKVTPGSQSYEKEAKPSDRNGTQPSGPENQVSKQLELKPSVQELAAHAASLAMTEASKNIKTPKSAYEFENSWRSFSGDS
ALRSQLLKVTTPSSLPQIFKNALTSPVLVDIIKCVASFFTEDMDLAVKYIENLTKVPRFNMLVMCLTSTEKNELLKIWED
VFCNKATPMEYAEVLDKLRSRYCLKQLEVLFQGPWSHPQFEK
;
;MGSSHHHHHHHHHHMTDVTIKGGENLYFQGMARSPSKHGRDQTQDFQGFFNDLQDWELSLKDKDKKIKQQPANSSNPSSE
TFRPSGSGKYDFAKKYRSIRDLSSSLIGESLLDSSSEKEQGNEFFKQKKFNEAIDCYSRSIALSPNAVTYANRAMAYLKI
KRYREAEVDCTEALNLDDRYIKAYSRRATARKELGMIKEAKEDAEFALRLEPESQELKKQYADIKSLLEKEIIEKATGAM
QSTAQELLKTSGLDKKIQKPKTEMTSKPVTLVAKTNRDIVQPVLGSNESSGKKLIENIQPEEKSKEGSMKIPAITEILDS
KKVTPGSQSYEKEAKPSDRNGTQPSGPENQVSKQLELKPSVQELAAHAASLAMTEASKNIKTPKSAYEFENSWRSFSGDS
ALRSQLLKVTTPSSLPQIFKNALTSPVLVDIIKCVASFFTEDMDLAVKYIENLTKVPRFNMLVMCLTSTEKNELLKIWED
VFCNKATPMEYAEVLDKLRSRYCLKQLEVLFQGPWSHPQFEK
;
G     ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        "ADENOSINE-5'-DIPHOSPHATE" 
_pdbx_entity_nonpoly.comp_id     ADP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  HIS n 
1 12  HIS n 
1 13  SER n 
1 14  SER n 
1 15  GLY n 
1 16  GLU n 
1 17  ASN n 
1 18  LEU n 
1 19  TYR n 
1 20  PHE n 
1 21  GLN n 
1 22  GLY n 
1 23  SER n 
1 24  HIS n 
1 25  MET n 
1 26  LEU n 
1 27  GLU n 
1 28  ASP n 
1 29  PRO n 
1 30  MET n 
1 31  GLU n 
1 32  LYS n 
1 33  VAL n 
1 34  LYS n 
1 35  ILE n 
1 36  GLU n 
1 37  GLU n 
1 38  ILE n 
1 39  GLN n 
1 40  SER n 
1 41  THR n 
1 42  ALA n 
1 43  LYS n 
1 44  LYS n 
1 45  GLN n 
1 46  ARG n 
1 47  ILE n 
1 48  ALA n 
1 49  THR n 
1 50  HIS n 
1 51  THR n 
1 52  HIS n 
1 53  ILE n 
1 54  LYS n 
1 55  GLY n 
1 56  LEU n 
1 57  GLY n 
1 58  LEU n 
1 59  GLU n 
1 60  PRO n 
1 61  THR n 
1 62  GLY n 
1 63  ILE n 
1 64  PRO n 
1 65  ILE n 
1 66  LYS n 
1 67  LEU n 
1 68  ALA n 
1 69  ALA n 
1 70  GLY n 
1 71  PHE n 
1 72  VAL n 
1 73  GLY n 
1 74  GLN n 
1 75  LEU n 
1 76  GLU n 
1 77  ALA n 
1 78  ARG n 
1 79  GLU n 
1 80  ALA n 
1 81  ALA n 
1 82  GLY n 
1 83  LEU n 
1 84  VAL n 
1 85  VAL n 
1 86  ASP n 
1 87  MET n 
1 88  ILE n 
1 89  LYS n 
1 90  GLN n 
1 91  LYS n 
1 92  LYS n 
1 93  MET n 
1 94  ALA n 
1 95  GLY n 
1 96  LYS n 
1 97  ALA n 
1 98  LEU n 
1 99  LEU n 
1 100 LEU n 
1 101 ALA n 
1 102 GLY n 
1 103 PRO n 
1 104 PRO n 
1 105 GLY n 
1 106 THR n 
1 107 GLY n 
1 108 LYS n 
1 109 THR n 
1 110 ALA n 
1 111 LEU n 
1 112 ALA n 
1 113 LEU n 
1 114 GLY n 
1 115 ILE n 
1 116 SER n 
1 117 GLN n 
1 118 GLU n 
1 119 LEU n 
1 120 GLY n 
1 121 SER n 
1 122 LYS n 
1 123 VAL n 
1 124 PRO n 
1 125 PHE n 
1 126 CYS n 
1 127 PRO n 
1 128 MET n 
1 129 VAL n 
1 130 GLY n 
1 131 SER n 
1 132 GLU n 
1 133 VAL n 
1 134 TYR n 
1 135 SER n 
1 136 SER n 
1 137 GLU n 
1 138 VAL n 
1 139 LYS n 
1 140 LYS n 
1 141 THR n 
1 142 GLU n 
1 143 VAL n 
1 144 LEU n 
1 145 MET n 
1 146 GLU n 
1 147 ASN n 
1 148 PHE n 
1 149 ARG n 
1 150 ARG n 
1 151 ALA n 
1 152 ILE n 
1 153 GLY n 
1 154 LEU n 
1 155 ARG n 
1 156 ILE n 
1 157 LYS n 
1 158 GLU n 
1 159 THR n 
1 160 LYS n 
1 161 GLU n 
1 162 VAL n 
1 163 TYR n 
1 164 GLU n 
1 165 GLY n 
1 166 GLU n 
1 167 VAL n 
1 168 THR n 
1 169 GLU n 
1 170 LEU n 
1 171 SER n 
1 172 PRO n 
1 173 GLU n 
1 174 GLU n 
1 175 THR n 
1 176 GLU n 
1 177 SER n 
1 178 LEU n 
1 179 THR n 
1 180 GLY n 
1 181 GLY n 
1 182 TYR n 
1 183 GLY n 
1 184 LYS n 
1 185 SER n 
1 186 ILE n 
1 187 SER n 
1 188 HIS n 
1 189 VAL n 
1 190 VAL n 
1 191 ILE n 
1 192 THR n 
1 193 LEU n 
1 194 LYS n 
1 195 THR n 
1 196 VAL n 
1 197 LYS n 
1 198 GLY n 
1 199 THR n 
1 200 LYS n 
1 201 HIS n 
1 202 LEU n 
1 203 LYS n 
1 204 LEU n 
1 205 ASP n 
1 206 PRO n 
1 207 THR n 
1 208 ILE n 
1 209 TYR n 
1 210 ASP n 
1 211 ALA n 
1 212 LEU n 
1 213 ILE n 
1 214 LYS n 
1 215 GLU n 
1 216 LYS n 
1 217 VAL n 
1 218 ALA n 
1 219 VAL n 
1 220 GLY n 
1 221 ASP n 
1 222 VAL n 
1 223 ILE n 
1 224 TYR n 
1 225 ILE n 
1 226 GLU n 
1 227 ALA n 
1 228 ASN n 
1 229 SER n 
1 230 GLY n 
1 231 ALA n 
1 232 VAL n 
1 233 LYS n 
1 234 ARG n 
1 235 VAL n 
1 236 GLY n 
1 237 ARG n 
1 238 SER n 
1 239 ASP n 
1 240 ALA n 
1 241 PHE n 
1 242 ALA n 
1 243 THR n 
1 244 GLU n 
1 245 PHE n 
1 246 ASP n 
1 247 LEU n 
1 248 GLU n 
1 249 ALA n 
1 250 GLU n 
1 251 GLU n 
1 252 TYR n 
1 253 VAL n 
1 254 PRO n 
1 255 LEU n 
1 256 PRO n 
1 257 LYS n 
1 258 GLY n 
1 259 GLU n 
1 260 VAL n 
1 261 HIS n 
1 262 LYS n 
1 263 LYS n 
1 264 LYS n 
1 265 GLU n 
1 266 ILE n 
1 267 VAL n 
1 268 GLN n 
1 269 ASP n 
1 270 VAL n 
1 271 THR n 
1 272 LEU n 
1 273 GLN n 
1 274 ASP n 
1 275 LEU n 
1 276 ASP n 
1 277 ALA n 
1 278 ALA n 
1 279 ASN n 
1 280 ALA n 
1 281 ARG n 
1 282 PRO n 
1 283 GLN n 
1 284 GLY n 
1 285 GLY n 
1 286 GLN n 
1 287 ASP n 
1 288 ILE n 
1 289 LEU n 
1 290 SER n 
1 291 LEU n 
1 292 MET n 
1 293 GLY n 
1 294 GLN n 
1 295 MET n 
1 296 MET n 
1 297 LYS n 
1 298 PRO n 
1 299 ARG n 
1 300 LYS n 
1 301 THR n 
1 302 GLU n 
1 303 ILE n 
1 304 THR n 
1 305 ASP n 
1 306 LYS n 
1 307 LEU n 
1 308 ARG n 
1 309 GLN n 
1 310 GLU n 
1 311 ILE n 
1 312 ASN n 
1 313 LYS n 
1 314 VAL n 
1 315 VAL n 
1 316 ASN n 
1 317 ARG n 
1 318 TYR n 
1 319 ILE n 
1 320 ASP n 
1 321 GLU n 
1 322 GLY n 
1 323 VAL n 
1 324 ALA n 
1 325 GLU n 
1 326 LEU n 
1 327 VAL n 
1 328 PRO n 
1 329 GLY n 
1 330 VAL n 
1 331 LEU n 
1 332 PHE n 
1 333 ILE n 
1 334 ASP n 
1 335 GLU n 
1 336 VAL n 
1 337 HIS n 
1 338 MET n 
1 339 LEU n 
1 340 ASP n 
1 341 MET n 
1 342 GLU n 
1 343 CYS n 
1 344 PHE n 
1 345 SER n 
1 346 TYR n 
1 347 LEU n 
1 348 ASN n 
1 349 ARG n 
1 350 ALA n 
1 351 LEU n 
1 352 GLU n 
1 353 SER n 
1 354 SER n 
1 355 LEU n 
1 356 SER n 
1 357 PRO n 
1 358 ILE n 
1 359 VAL n 
1 360 ILE n 
1 361 PHE n 
1 362 ALA n 
1 363 THR n 
1 364 ASN n 
1 365 ARG n 
1 366 GLY n 
1 367 VAL n 
1 368 CYS n 
1 369 ASN n 
1 370 VAL n 
1 371 ARG n 
1 372 GLY n 
1 373 THR n 
1 374 ASP n 
1 375 MET n 
1 376 PRO n 
1 377 SER n 
1 378 PRO n 
1 379 HIS n 
1 380 GLY n 
1 381 VAL n 
1 382 PRO n 
1 383 ILE n 
1 384 ASP n 
1 385 LEU n 
1 386 LEU n 
1 387 ASP n 
1 388 ARG n 
1 389 LEU n 
1 390 VAL n 
1 391 ILE n 
1 392 ILE n 
1 393 ARG n 
1 394 THR n 
1 395 GLN n 
1 396 ILE n 
1 397 TYR n 
1 398 ASP n 
1 399 PRO n 
1 400 SER n 
1 401 GLU n 
1 402 MET n 
1 403 ILE n 
1 404 GLN n 
1 405 ILE n 
1 406 ILE n 
1 407 ALA n 
1 408 ILE n 
1 409 ARG n 
1 410 ALA n 
1 411 GLN n 
1 412 VAL n 
1 413 GLU n 
1 414 GLU n 
1 415 LEU n 
1 416 THR n 
1 417 VAL n 
1 418 ASP n 
1 419 GLU n 
1 420 GLU n 
1 421 CYS n 
1 422 LEU n 
1 423 VAL n 
1 424 LEU n 
1 425 LEU n 
1 426 GLY n 
1 427 GLU n 
1 428 ILE n 
1 429 GLY n 
1 430 GLN n 
1 431 ARG n 
1 432 THR n 
1 433 SER n 
1 434 LEU n 
1 435 ARG n 
1 436 HIS n 
1 437 ALA n 
1 438 VAL n 
1 439 GLN n 
1 440 LEU n 
1 441 LEU n 
1 442 SER n 
1 443 PRO n 
1 444 ALA n 
1 445 SER n 
1 446 ILE n 
1 447 VAL n 
1 448 ALA n 
1 449 LYS n 
1 450 MET n 
1 451 ASN n 
1 452 GLY n 
1 453 ARG n 
1 454 ASP n 
1 455 ASN n 
1 456 ILE n 
1 457 CYS n 
1 458 LYS n 
1 459 ALA n 
1 460 ASP n 
1 461 ILE n 
1 462 GLU n 
1 463 GLU n 
1 464 VAL n 
1 465 THR n 
1 466 SER n 
1 467 LEU n 
1 468 TYR n 
1 469 LEU n 
1 470 ASP n 
1 471 ALA n 
1 472 LYS n 
1 473 SER n 
1 474 SER n 
1 475 ALA n 
1 476 LYS n 
1 477 LEU n 
1 478 LEU n 
1 479 HIS n 
1 480 GLU n 
1 481 GLN n 
1 482 GLN n 
1 483 GLU n 
1 484 LYS n 
1 485 TYR n 
1 486 ILE n 
1 487 SER n 
2 1   MET n 
2 2   ALA n 
2 3   ASP n 
2 4   LEU n 
2 5   ASN n 
2 6   TRP n 
2 7   ILE n 
2 8   SER n 
2 9   ALA n 
2 10  GLY n 
2 11  HIS n 
2 12  ALA n 
2 13  ILE n 
2 14  ALA n 
2 15  ASP n 
2 16  VAL n 
2 17  GLY n 
2 18  THR n 
2 19  MET n 
2 20  ALA n 
2 21  GLU n 
2 22  LEU n 
2 23  LYS n 
2 24  LEU n 
2 25  SER n 
2 26  GLU n 
2 27  SER n 
2 28  ARG n 
2 29  ASP n 
2 30  LEU n 
2 31  THR n 
2 32  ARG n 
2 33  VAL n 
2 34  GLU n 
2 35  ARG n 
2 36  ILE n 
2 37  GLY n 
2 38  ALA n 
2 39  HIS n 
2 40  SER n 
2 41  HIS n 
2 42  ILE n 
2 43  ARG n 
2 44  GLY n 
2 45  LEU n 
2 46  GLY n 
2 47  LEU n 
2 48  ASP n 
2 49  SER n 
2 50  ALA n 
2 51  LEU n 
2 52  GLU n 
2 53  PRO n 
2 54  ARG n 
2 55  ALA n 
2 56  VAL n 
2 57  SER n 
2 58  GLU n 
2 59  GLY n 
2 60  MET n 
2 61  VAL n 
2 62  GLY n 
2 63  GLN n 
2 64  VAL n 
2 65  LYS n 
2 66  ALA n 
2 67  ARG n 
2 68  LYS n 
2 69  ALA n 
2 70  ALA n 
2 71  GLY n 
2 72  VAL n 
2 73  ILE n 
2 74  LEU n 
2 75  GLN n 
2 76  MET n 
2 77  ILE n 
2 78  ARG n 
2 79  GLU n 
2 80  GLY n 
2 81  LYS n 
2 82  ILE n 
2 83  ALA n 
2 84  GLY n 
2 85  ARG n 
2 86  ALA n 
2 87  ILE n 
2 88  LEU n 
2 89  ILE n 
2 90  ALA n 
2 91  GLY n 
2 92  GLN n 
2 93  PRO n 
2 94  GLY n 
2 95  THR n 
2 96  GLY n 
2 97  LYS n 
2 98  THR n 
2 99  ALA n 
2 100 ILE n 
2 101 ALA n 
2 102 MET n 
2 103 GLY n 
2 104 MET n 
2 105 ALA n 
2 106 LYS n 
2 107 SER n 
2 108 LEU n 
2 109 GLY n 
2 110 LEU n 
2 111 GLU n 
2 112 THR n 
2 113 PRO n 
2 114 PHE n 
2 115 ALA n 
2 116 MET n 
2 117 ILE n 
2 118 ALA n 
2 119 GLY n 
2 120 SER n 
2 121 GLU n 
2 122 ILE n 
2 123 PHE n 
2 124 SER n 
2 125 LEU n 
2 126 GLU n 
2 127 MET n 
2 128 SER n 
2 129 LYS n 
2 130 THR n 
2 131 GLU n 
2 132 ALA n 
2 133 LEU n 
2 134 THR n 
2 135 GLN n 
2 136 SER n 
2 137 PHE n 
2 138 ARG n 
2 139 LYS n 
2 140 ALA n 
2 141 ILE n 
2 142 GLY n 
2 143 VAL n 
2 144 ARG n 
2 145 ILE n 
2 146 LYS n 
2 147 GLU n 
2 148 GLU n 
2 149 THR n 
2 150 GLU n 
2 151 VAL n 
2 152 ILE n 
2 153 GLU n 
2 154 GLY n 
2 155 GLU n 
2 156 VAL n 
2 157 VAL n 
2 158 GLU n 
2 159 VAL n 
2 160 GLN n 
2 161 ILE n 
2 162 ASP n 
2 163 ARG n 
2 164 PRO n 
2 165 ALA n 
2 166 SER n 
2 167 SER n 
2 168 GLY n 
2 169 VAL n 
2 170 ALA n 
2 171 SER n 
2 172 LYS n 
2 173 SER n 
2 174 GLY n 
2 175 LYS n 
2 176 MET n 
2 177 THR n 
2 178 MET n 
2 179 LYS n 
2 180 THR n 
2 181 THR n 
2 182 ASP n 
2 183 MET n 
2 184 GLU n 
2 185 THR n 
2 186 VAL n 
2 187 TYR n 
2 188 ASP n 
2 189 MET n 
2 190 GLY n 
2 191 ALA n 
2 192 LYS n 
2 193 MET n 
2 194 ILE n 
2 195 GLU n 
2 196 ALA n 
2 197 LEU n 
2 198 ASN n 
2 199 LYS n 
2 200 GLU n 
2 201 LYS n 
2 202 VAL n 
2 203 GLN n 
2 204 SER n 
2 205 GLY n 
2 206 ASP n 
2 207 VAL n 
2 208 ILE n 
2 209 ALA n 
2 210 ILE n 
2 211 ASP n 
2 212 LYS n 
2 213 ALA n 
2 214 THR n 
2 215 GLY n 
2 216 LYS n 
2 217 ILE n 
2 218 THR n 
2 219 LYS n 
2 220 LEU n 
2 221 GLY n 
2 222 ARG n 
2 223 SER n 
2 224 PHE n 
2 225 SER n 
2 226 ARG n 
2 227 SER n 
2 228 ARG n 
2 229 ASP n 
2 230 TYR n 
2 231 ASP n 
2 232 ALA n 
2 233 MET n 
2 234 GLY n 
2 235 ALA n 
2 236 GLN n 
2 237 THR n 
2 238 LYS n 
2 239 PHE n 
2 240 VAL n 
2 241 GLN n 
2 242 CYS n 
2 243 PRO n 
2 244 GLU n 
2 245 GLY n 
2 246 GLU n 
2 247 LEU n 
2 248 GLN n 
2 249 LYS n 
2 250 ARG n 
2 251 LYS n 
2 252 GLU n 
2 253 VAL n 
2 254 VAL n 
2 255 HIS n 
2 256 CYS n 
2 257 VAL n 
2 258 THR n 
2 259 LEU n 
2 260 HIS n 
2 261 GLU n 
2 262 ILE n 
2 263 ASP n 
2 264 VAL n 
2 265 ILE n 
2 266 ASN n 
2 267 SER n 
2 268 ARG n 
2 269 THR n 
2 270 GLN n 
2 271 GLY n 
2 272 PHE n 
2 273 LEU n 
2 274 ALA n 
2 275 LEU n 
2 276 PHE n 
2 277 THR n 
2 278 GLY n 
2 279 ASP n 
2 280 THR n 
2 281 GLY n 
2 282 GLU n 
2 283 ILE n 
2 284 ARG n 
2 285 SER n 
2 286 GLU n 
2 287 VAL n 
2 288 ARG n 
2 289 GLU n 
2 290 GLN n 
2 291 ILE n 
2 292 ASP n 
2 293 THR n 
2 294 LYS n 
2 295 VAL n 
2 296 ALA n 
2 297 GLU n 
2 298 TRP n 
2 299 ARG n 
2 300 GLU n 
2 301 GLU n 
2 302 GLY n 
2 303 LYS n 
2 304 ALA n 
2 305 GLU n 
2 306 ILE n 
2 307 VAL n 
2 308 PRO n 
2 309 GLY n 
2 310 VAL n 
2 311 LEU n 
2 312 PHE n 
2 313 ILE n 
2 314 ASP n 
2 315 GLU n 
2 316 VAL n 
2 317 HIS n 
2 318 MET n 
2 319 LEU n 
2 320 ASP n 
2 321 ILE n 
2 322 GLU n 
2 323 CYS n 
2 324 PHE n 
2 325 SER n 
2 326 PHE n 
2 327 LEU n 
2 328 ASN n 
2 329 ARG n 
2 330 ALA n 
2 331 LEU n 
2 332 GLU n 
2 333 ASN n 
2 334 GLU n 
2 335 MET n 
2 336 SER n 
2 337 PRO n 
2 338 ILE n 
2 339 LEU n 
2 340 VAL n 
2 341 VAL n 
2 342 ALA n 
2 343 THR n 
2 344 ASN n 
2 345 ARG n 
2 346 GLY n 
2 347 VAL n 
2 348 THR n 
2 349 THR n 
2 350 ILE n 
2 351 ARG n 
2 352 GLY n 
2 353 THR n 
2 354 ASN n 
2 355 GLN n 
2 356 LYS n 
2 357 SER n 
2 358 PRO n 
2 359 HIS n 
2 360 GLY n 
2 361 ILE n 
2 362 PRO n 
2 363 ILE n 
2 364 ASP n 
2 365 LEU n 
2 366 LEU n 
2 367 ASP n 
2 368 ARG n 
2 369 LEU n 
2 370 LEU n 
2 371 ILE n 
2 372 ILE n 
2 373 THR n 
2 374 THR n 
2 375 GLN n 
2 376 PRO n 
2 377 TYR n 
2 378 THR n 
2 379 ASP n 
2 380 ASP n 
2 381 ASP n 
2 382 ILE n 
2 383 ARG n 
2 384 LYS n 
2 385 ILE n 
2 386 LEU n 
2 387 GLU n 
2 388 ILE n 
2 389 ARG n 
2 390 CYS n 
2 391 GLN n 
2 392 GLU n 
2 393 GLU n 
2 394 ASP n 
2 395 VAL n 
2 396 GLU n 
2 397 MET n 
2 398 ASN n 
2 399 GLU n 
2 400 GLU n 
2 401 ALA n 
2 402 LYS n 
2 403 GLN n 
2 404 LEU n 
2 405 LEU n 
2 406 THR n 
2 407 LEU n 
2 408 ILE n 
2 409 GLY n 
2 410 ARG n 
2 411 ASP n 
2 412 THR n 
2 413 SER n 
2 414 LEU n 
2 415 ARG n 
2 416 TYR n 
2 417 ALA n 
2 418 ILE n 
2 419 HIS n 
2 420 LEU n 
2 421 ILE n 
2 422 THR n 
2 423 ALA n 
2 424 ALA n 
2 425 ALA n 
2 426 LEU n 
2 427 SER n 
2 428 CYS n 
2 429 GLN n 
2 430 LYS n 
2 431 ARG n 
2 432 LYS n 
2 433 GLY n 
2 434 LYS n 
2 435 VAL n 
2 436 VAL n 
2 437 GLU n 
2 438 VAL n 
2 439 GLU n 
2 440 ASP n 
2 441 ILE n 
2 442 GLN n 
2 443 ARG n 
2 444 VAL n 
2 445 TYR n 
2 446 ARG n 
2 447 LEU n 
2 448 PHE n 
2 449 LEU n 
2 450 ASP n 
2 451 VAL n 
2 452 ARG n 
2 453 ARG n 
2 454 SER n 
2 455 MET n 
2 456 GLN n 
2 457 TYR n 
2 458 LEU n 
2 459 VAL n 
2 460 GLU n 
2 461 TYR n 
2 462 GLN n 
2 463 SER n 
2 464 GLN n 
2 465 TYR n 
2 466 MET n 
2 467 PHE n 
2 468 SER n 
2 469 GLU n 
2 470 PRO n 
2 471 ILE n 
2 472 LYS n 
2 473 ASN n 
2 474 ASP n 
2 475 GLU n 
2 476 ALA n 
2 477 ALA n 
2 478 ALA n 
2 479 GLU n 
2 480 ASP n 
2 481 GLU n 
2 482 GLN n 
2 483 ASP n 
2 484 ALA n 
2 485 MET n 
2 486 GLN n 
2 487 ILE n 
3 1   MET n 
3 2   GLY n 
3 3   SER n 
3 4   SER n 
3 5   HIS n 
3 6   HIS n 
3 7   HIS n 
3 8   HIS n 
3 9   HIS n 
3 10  HIS n 
3 11  HIS n 
3 12  HIS n 
3 13  HIS n 
3 14  HIS n 
3 15  MET n 
3 16  THR n 
3 17  ASP n 
3 18  VAL n 
3 19  THR n 
3 20  ILE n 
3 21  LYS n 
3 22  GLY n 
3 23  GLY n 
3 24  GLU n 
3 25  ASN n 
3 26  LEU n 
3 27  TYR n 
3 28  PHE n 
3 29  GLN n 
3 30  GLY n 
3 31  MET n 
3 32  ALA n 
3 33  ARG n 
3 34  SER n 
3 35  PRO n 
3 36  SER n 
3 37  LYS n 
3 38  HIS n 
3 39  GLY n 
3 40  ARG n 
3 41  ASP n 
3 42  GLN n 
3 43  THR n 
3 44  GLN n 
3 45  ASP n 
3 46  PHE n 
3 47  GLN n 
3 48  GLY n 
3 49  PHE n 
3 50  PHE n 
3 51  ASN n 
3 52  ASP n 
3 53  LEU n 
3 54  GLN n 
3 55  ASP n 
3 56  TRP n 
3 57  GLU n 
3 58  LEU n 
3 59  SER n 
3 60  LEU n 
3 61  LYS n 
3 62  ASP n 
3 63  LYS n 
3 64  ASP n 
3 65  LYS n 
3 66  LYS n 
3 67  ILE n 
3 68  LYS n 
3 69  GLN n 
3 70  GLN n 
3 71  PRO n 
3 72  ALA n 
3 73  ASN n 
3 74  SER n 
3 75  SER n 
3 76  ASN n 
3 77  PRO n 
3 78  SER n 
3 79  SER n 
3 80  GLU n 
3 81  THR n 
3 82  PHE n 
3 83  ARG n 
3 84  PRO n 
3 85  SER n 
3 86  GLY n 
3 87  SER n 
3 88  GLY n 
3 89  LYS n 
3 90  TYR n 
3 91  ASP n 
3 92  PHE n 
3 93  ALA n 
3 94  LYS n 
3 95  LYS n 
3 96  TYR n 
3 97  ARG n 
3 98  SER n 
3 99  ILE n 
3 100 ARG n 
3 101 ASP n 
3 102 LEU n 
3 103 SER n 
3 104 SER n 
3 105 SER n 
3 106 LEU n 
3 107 ILE n 
3 108 GLY n 
3 109 GLU n 
3 110 SER n 
3 111 LEU n 
3 112 LEU n 
3 113 ASP n 
3 114 SER n 
3 115 SER n 
3 116 SER n 
3 117 GLU n 
3 118 LYS n 
3 119 GLU n 
3 120 GLN n 
3 121 GLY n 
3 122 ASN n 
3 123 GLU n 
3 124 PHE n 
3 125 PHE n 
3 126 LYS n 
3 127 GLN n 
3 128 LYS n 
3 129 LYS n 
3 130 PHE n 
3 131 ASN n 
3 132 GLU n 
3 133 ALA n 
3 134 ILE n 
3 135 ASP n 
3 136 CYS n 
3 137 TYR n 
3 138 SER n 
3 139 ARG n 
3 140 SER n 
3 141 ILE n 
3 142 ALA n 
3 143 LEU n 
3 144 SER n 
3 145 PRO n 
3 146 ASN n 
3 147 ALA n 
3 148 VAL n 
3 149 THR n 
3 150 TYR n 
3 151 ALA n 
3 152 ASN n 
3 153 ARG n 
3 154 ALA n 
3 155 MET n 
3 156 ALA n 
3 157 TYR n 
3 158 LEU n 
3 159 LYS n 
3 160 ILE n 
3 161 LYS n 
3 162 ARG n 
3 163 TYR n 
3 164 ARG n 
3 165 GLU n 
3 166 ALA n 
3 167 GLU n 
3 168 VAL n 
3 169 ASP n 
3 170 CYS n 
3 171 THR n 
3 172 GLU n 
3 173 ALA n 
3 174 LEU n 
3 175 ASN n 
3 176 LEU n 
3 177 ASP n 
3 178 ASP n 
3 179 ARG n 
3 180 TYR n 
3 181 ILE n 
3 182 LYS n 
3 183 ALA n 
3 184 TYR n 
3 185 SER n 
3 186 ARG n 
3 187 ARG n 
3 188 ALA n 
3 189 THR n 
3 190 ALA n 
3 191 ARG n 
3 192 LYS n 
3 193 GLU n 
3 194 LEU n 
3 195 GLY n 
3 196 MET n 
3 197 ILE n 
3 198 LYS n 
3 199 GLU n 
3 200 ALA n 
3 201 LYS n 
3 202 GLU n 
3 203 ASP n 
3 204 ALA n 
3 205 GLU n 
3 206 PHE n 
3 207 ALA n 
3 208 LEU n 
3 209 ARG n 
3 210 LEU n 
3 211 GLU n 
3 212 PRO n 
3 213 GLU n 
3 214 SER n 
3 215 GLN n 
3 216 GLU n 
3 217 LEU n 
3 218 LYS n 
3 219 LYS n 
3 220 GLN n 
3 221 TYR n 
3 222 ALA n 
3 223 ASP n 
3 224 ILE n 
3 225 LYS n 
3 226 SER n 
3 227 LEU n 
3 228 LEU n 
3 229 GLU n 
3 230 LYS n 
3 231 GLU n 
3 232 ILE n 
3 233 ILE n 
3 234 GLU n 
3 235 LYS n 
3 236 ALA n 
3 237 THR n 
3 238 GLY n 
3 239 ALA n 
3 240 MET n 
3 241 GLN n 
3 242 SER n 
3 243 THR n 
3 244 ALA n 
3 245 GLN n 
3 246 GLU n 
3 247 LEU n 
3 248 LEU n 
3 249 LYS n 
3 250 THR n 
3 251 SER n 
3 252 GLY n 
3 253 LEU n 
3 254 ASP n 
3 255 LYS n 
3 256 LYS n 
3 257 ILE n 
3 258 GLN n 
3 259 LYS n 
3 260 PRO n 
3 261 LYS n 
3 262 THR n 
3 263 GLU n 
3 264 MET n 
3 265 THR n 
3 266 SER n 
3 267 LYS n 
3 268 PRO n 
3 269 VAL n 
3 270 THR n 
3 271 LEU n 
3 272 VAL n 
3 273 ALA n 
3 274 LYS n 
3 275 THR n 
3 276 ASN n 
3 277 ARG n 
3 278 ASP n 
3 279 ILE n 
3 280 VAL n 
3 281 GLN n 
3 282 PRO n 
3 283 VAL n 
3 284 LEU n 
3 285 GLY n 
3 286 SER n 
3 287 ASN n 
3 288 GLU n 
3 289 SER n 
3 290 SER n 
3 291 GLY n 
3 292 LYS n 
3 293 LYS n 
3 294 LEU n 
3 295 ILE n 
3 296 GLU n 
3 297 ASN n 
3 298 ILE n 
3 299 GLN n 
3 300 PRO n 
3 301 GLU n 
3 302 GLU n 
3 303 LYS n 
3 304 SER n 
3 305 LYS n 
3 306 GLU n 
3 307 GLY n 
3 308 SER n 
3 309 MET n 
3 310 LYS n 
3 311 ILE n 
3 312 PRO n 
3 313 ALA n 
3 314 ILE n 
3 315 THR n 
3 316 GLU n 
3 317 ILE n 
3 318 LEU n 
3 319 ASP n 
3 320 SER n 
3 321 LYS n 
3 322 LYS n 
3 323 VAL n 
3 324 THR n 
3 325 PRO n 
3 326 GLY n 
3 327 SER n 
3 328 GLN n 
3 329 SER n 
3 330 TYR n 
3 331 GLU n 
3 332 LYS n 
3 333 GLU n 
3 334 ALA n 
3 335 LYS n 
3 336 PRO n 
3 337 SER n 
3 338 ASP n 
3 339 ARG n 
3 340 ASN n 
3 341 GLY n 
3 342 THR n 
3 343 GLN n 
3 344 PRO n 
3 345 SER n 
3 346 GLY n 
3 347 PRO n 
3 348 GLU n 
3 349 ASN n 
3 350 GLN n 
3 351 VAL n 
3 352 SER n 
3 353 LYS n 
3 354 GLN n 
3 355 LEU n 
3 356 GLU n 
3 357 LEU n 
3 358 LYS n 
3 359 PRO n 
3 360 SER n 
3 361 VAL n 
3 362 GLN n 
3 363 GLU n 
3 364 LEU n 
3 365 ALA n 
3 366 ALA n 
3 367 HIS n 
3 368 ALA n 
3 369 ALA n 
3 370 SER n 
3 371 LEU n 
3 372 ALA n 
3 373 MET n 
3 374 THR n 
3 375 GLU n 
3 376 ALA n 
3 377 SER n 
3 378 LYS n 
3 379 ASN n 
3 380 ILE n 
3 381 LYS n 
3 382 THR n 
3 383 PRO n 
3 384 LYS n 
3 385 SER n 
3 386 ALA n 
3 387 TYR n 
3 388 GLU n 
3 389 PHE n 
3 390 GLU n 
3 391 ASN n 
3 392 SER n 
3 393 TRP n 
3 394 ARG n 
3 395 SER n 
3 396 PHE n 
3 397 SER n 
3 398 GLY n 
3 399 ASP n 
3 400 SER n 
3 401 ALA n 
3 402 LEU n 
3 403 ARG n 
3 404 SER n 
3 405 GLN n 
3 406 LEU n 
3 407 LEU n 
3 408 LYS n 
3 409 VAL n 
3 410 THR n 
3 411 THR n 
3 412 PRO n 
3 413 SER n 
3 414 SER n 
3 415 LEU n 
3 416 PRO n 
3 417 GLN n 
3 418 ILE n 
3 419 PHE n 
3 420 LYS n 
3 421 ASN n 
3 422 ALA n 
3 423 LEU n 
3 424 THR n 
3 425 SER n 
3 426 PRO n 
3 427 VAL n 
3 428 LEU n 
3 429 VAL n 
3 430 ASP n 
3 431 ILE n 
3 432 ILE n 
3 433 LYS n 
3 434 CYS n 
3 435 VAL n 
3 436 ALA n 
3 437 SER n 
3 438 PHE n 
3 439 PHE n 
3 440 THR n 
3 441 GLU n 
3 442 ASP n 
3 443 MET n 
3 444 ASP n 
3 445 LEU n 
3 446 ALA n 
3 447 VAL n 
3 448 LYS n 
3 449 TYR n 
3 450 ILE n 
3 451 GLU n 
3 452 ASN n 
3 453 LEU n 
3 454 THR n 
3 455 LYS n 
3 456 VAL n 
3 457 PRO n 
3 458 ARG n 
3 459 PHE n 
3 460 ASN n 
3 461 MET n 
3 462 LEU n 
3 463 VAL n 
3 464 MET n 
3 465 CYS n 
3 466 LEU n 
3 467 THR n 
3 468 SER n 
3 469 THR n 
3 470 GLU n 
3 471 LYS n 
3 472 ASN n 
3 473 GLU n 
3 474 LEU n 
3 475 LEU n 
3 476 LYS n 
3 477 ILE n 
3 478 TRP n 
3 479 GLU n 
3 480 ASP n 
3 481 VAL n 
3 482 PHE n 
3 483 CYS n 
3 484 ASN n 
3 485 LYS n 
3 486 ALA n 
3 487 THR n 
3 488 PRO n 
3 489 MET n 
3 490 GLU n 
3 491 TYR n 
3 492 ALA n 
3 493 GLU n 
3 494 VAL n 
3 495 LEU n 
3 496 ASP n 
3 497 LYS n 
3 498 LEU n 
3 499 ARG n 
3 500 SER n 
3 501 ARG n 
3 502 TYR n 
3 503 CYS n 
3 504 LEU n 
3 505 LYS n 
3 506 GLN n 
3 507 LEU n 
3 508 GLU n 
3 509 VAL n 
3 510 LEU n 
3 511 PHE n 
3 512 GLN n 
3 513 GLY n 
3 514 PRO n 
3 515 TRP n 
3 516 SER n 
3 517 HIS n 
3 518 PRO n 
3 519 GLN n 
3 520 PHE n 
3 521 GLU n 
3 522 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 487 'thale cress' ? 'RIN1, RVB1, TIP49a, At5g22330'                                 ? ? ? ? ? ? 
'Arabidopsis thaliana' 3702 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 487 'thale cress' ? 'ISE4, At5g67630, K9I9.20, K9I9_20'                             ? ? ? ? ? ? 
'Arabidopsis thaliana' 3702 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 522 'thale cress' ? 'TPR5, tetratricopeptide repeat 5, At1g56440, F13N6.2, F13N6_2' ? ? ? ? ? ? 
'Arabidopsis thaliana' 3702 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ADP non-polymer         n "ADENOSINE-5'-DIPHOSPHATE" ? 'C10 H15 N5 O10 P2' 427.201 
ALA 'L-peptide linking' y ALANINE                    ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                   ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                 ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'            ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                   ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                  ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'            ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                    ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                  ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                 ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                    ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                     ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                 ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE              ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                    ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                     ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                  ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                 ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                   ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                     ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -28 ?   ?   ?   A . n 
A 1 2   GLY 2   -27 ?   ?   ?   A . n 
A 1 3   SER 3   -26 ?   ?   ?   A . n 
A 1 4   SER 4   -25 ?   ?   ?   A . n 
A 1 5   HIS 5   -24 ?   ?   ?   A . n 
A 1 6   HIS 6   -23 ?   ?   ?   A . n 
A 1 7   HIS 7   -22 ?   ?   ?   A . n 
A 1 8   HIS 8   -21 ?   ?   ?   A . n 
A 1 9   HIS 9   -20 ?   ?   ?   A . n 
A 1 10  HIS 10  -19 ?   ?   ?   A . n 
A 1 11  HIS 11  -18 ?   ?   ?   A . n 
A 1 12  HIS 12  -17 ?   ?   ?   A . n 
A 1 13  SER 13  -16 ?   ?   ?   A . n 
A 1 14  SER 14  -15 ?   ?   ?   A . n 
A 1 15  GLY 15  -14 ?   ?   ?   A . n 
A 1 16  GLU 16  -13 ?   ?   ?   A . n 
A 1 17  ASN 17  -12 ?   ?   ?   A . n 
A 1 18  LEU 18  -11 ?   ?   ?   A . n 
A 1 19  TYR 19  -10 ?   ?   ?   A . n 
A 1 20  PHE 20  -9  ?   ?   ?   A . n 
A 1 21  GLN 21  -8  ?   ?   ?   A . n 
A 1 22  GLY 22  -7  ?   ?   ?   A . n 
A 1 23  SER 23  -6  ?   ?   ?   A . n 
A 1 24  HIS 24  -5  ?   ?   ?   A . n 
A 1 25  MET 25  -4  ?   ?   ?   A . n 
A 1 26  LEU 26  -3  ?   ?   ?   A . n 
A 1 27  GLU 27  -2  ?   ?   ?   A . n 
A 1 28  ASP 28  -1  ?   ?   ?   A . n 
A 1 29  PRO 29  0   ?   ?   ?   A . n 
A 1 30  MET 30  1   ?   ?   ?   A . n 
A 1 31  GLU 31  2   ?   ?   ?   A . n 
A 1 32  LYS 32  3   ?   ?   ?   A . n 
A 1 33  VAL 33  4   ?   ?   ?   A . n 
A 1 34  LYS 34  5   ?   ?   ?   A . n 
A 1 35  ILE 35  6   ?   ?   ?   A . n 
A 1 36  GLU 36  7   ?   ?   ?   A . n 
A 1 37  GLU 37  8   ?   ?   ?   A . n 
A 1 38  ILE 38  9   ?   ?   ?   A . n 
A 1 39  GLN 39  10  ?   ?   ?   A . n 
A 1 40  SER 40  11  ?   ?   ?   A . n 
A 1 41  THR 41  12  ?   ?   ?   A . n 
A 1 42  ALA 42  13  ?   ?   ?   A . n 
A 1 43  LYS 43  14  ?   ?   ?   A . n 
A 1 44  LYS 44  15  ?   ?   ?   A . n 
A 1 45  GLN 45  16  ?   ?   ?   A . n 
A 1 46  ARG 46  17  ?   ?   ?   A . n 
A 1 47  ILE 47  18  18  ILE ILE A . n 
A 1 48  ALA 48  19  19  ALA ALA A . n 
A 1 49  THR 49  20  20  THR THR A . n 
A 1 50  HIS 50  21  21  HIS HIS A . n 
A 1 51  THR 51  22  22  THR THR A . n 
A 1 52  HIS 52  23  23  HIS HIS A . n 
A 1 53  ILE 53  24  24  ILE ILE A . n 
A 1 54  LYS 54  25  25  LYS LYS A . n 
A 1 55  GLY 55  26  26  GLY GLY A . n 
A 1 56  LEU 56  27  27  LEU LEU A . n 
A 1 57  GLY 57  28  28  GLY GLY A . n 
A 1 58  LEU 58  29  29  LEU LEU A . n 
A 1 59  GLU 59  30  30  GLU GLU A . n 
A 1 60  PRO 60  31  31  PRO PRO A . n 
A 1 61  THR 61  32  32  THR THR A . n 
A 1 62  GLY 62  33  33  GLY GLY A . n 
A 1 63  ILE 63  34  34  ILE ILE A . n 
A 1 64  PRO 64  35  35  PRO PRO A . n 
A 1 65  ILE 65  36  36  ILE ILE A . n 
A 1 66  LYS 66  37  37  LYS LYS A . n 
A 1 67  LEU 67  38  38  LEU LEU A . n 
A 1 68  ALA 68  39  39  ALA ALA A . n 
A 1 69  ALA 69  40  40  ALA ALA A . n 
A 1 70  GLY 70  41  41  GLY GLY A . n 
A 1 71  PHE 71  42  42  PHE PHE A . n 
A 1 72  VAL 72  43  43  VAL VAL A . n 
A 1 73  GLY 73  44  44  GLY GLY A . n 
A 1 74  GLN 74  45  45  GLN GLN A . n 
A 1 75  LEU 75  46  46  LEU LEU A . n 
A 1 76  GLU 76  47  47  GLU GLU A . n 
A 1 77  ALA 77  48  48  ALA ALA A . n 
A 1 78  ARG 78  49  49  ARG ARG A . n 
A 1 79  GLU 79  50  50  GLU GLU A . n 
A 1 80  ALA 80  51  51  ALA ALA A . n 
A 1 81  ALA 81  52  52  ALA ALA A . n 
A 1 82  GLY 82  53  53  GLY GLY A . n 
A 1 83  LEU 83  54  54  LEU LEU A . n 
A 1 84  VAL 84  55  55  VAL VAL A . n 
A 1 85  VAL 85  56  56  VAL VAL A . n 
A 1 86  ASP 86  57  57  ASP ASP A . n 
A 1 87  MET 87  58  58  MET MET A . n 
A 1 88  ILE 88  59  59  ILE ILE A . n 
A 1 89  LYS 89  60  60  LYS LYS A . n 
A 1 90  GLN 90  61  61  GLN GLN A . n 
A 1 91  LYS 91  62  62  LYS LYS A . n 
A 1 92  LYS 92  63  63  LYS LYS A . n 
A 1 93  MET 93  64  64  MET MET A . n 
A 1 94  ALA 94  65  65  ALA ALA A . n 
A 1 95  GLY 95  66  66  GLY GLY A . n 
A 1 96  LYS 96  67  67  LYS LYS A . n 
A 1 97  ALA 97  68  68  ALA ALA A . n 
A 1 98  LEU 98  69  69  LEU LEU A . n 
A 1 99  LEU 99  70  70  LEU LEU A . n 
A 1 100 LEU 100 71  71  LEU LEU A . n 
A 1 101 ALA 101 72  72  ALA ALA A . n 
A 1 102 GLY 102 73  73  GLY GLY A . n 
A 1 103 PRO 103 74  74  PRO PRO A . n 
A 1 104 PRO 104 75  75  PRO PRO A . n 
A 1 105 GLY 105 76  76  GLY GLY A . n 
A 1 106 THR 106 77  77  THR THR A . n 
A 1 107 GLY 107 78  78  GLY GLY A . n 
A 1 108 LYS 108 79  79  LYS LYS A . n 
A 1 109 THR 109 80  80  THR THR A . n 
A 1 110 ALA 110 81  81  ALA ALA A . n 
A 1 111 LEU 111 82  82  LEU LEU A . n 
A 1 112 ALA 112 83  83  ALA ALA A . n 
A 1 113 LEU 113 84  84  LEU LEU A . n 
A 1 114 GLY 114 85  85  GLY GLY A . n 
A 1 115 ILE 115 86  86  ILE ILE A . n 
A 1 116 SER 116 87  87  SER SER A . n 
A 1 117 GLN 117 88  88  GLN GLN A . n 
A 1 118 GLU 118 89  89  GLU GLU A . n 
A 1 119 LEU 119 90  90  LEU LEU A . n 
A 1 120 GLY 120 91  91  GLY GLY A . n 
A 1 121 SER 121 92  92  SER SER A . n 
A 1 122 LYS 122 93  93  LYS LYS A . n 
A 1 123 VAL 123 94  94  VAL VAL A . n 
A 1 124 PRO 124 95  95  PRO PRO A . n 
A 1 125 PHE 125 96  96  PHE PHE A . n 
A 1 126 CYS 126 97  97  CYS CYS A . n 
A 1 127 PRO 127 98  98  PRO PRO A . n 
A 1 128 MET 128 99  99  MET MET A . n 
A 1 129 VAL 129 100 100 VAL VAL A . n 
A 1 130 GLY 130 101 101 GLY GLY A . n 
A 1 131 SER 131 102 102 SER SER A . n 
A 1 132 GLU 132 103 103 GLU GLU A . n 
A 1 133 VAL 133 104 104 VAL VAL A . n 
A 1 134 TYR 134 105 105 TYR TYR A . n 
A 1 135 SER 135 106 106 SER SER A . n 
A 1 136 SER 136 107 107 SER SER A . n 
A 1 137 GLU 137 108 108 GLU GLU A . n 
A 1 138 VAL 138 109 109 VAL VAL A . n 
A 1 139 LYS 139 110 110 LYS LYS A . n 
A 1 140 LYS 140 111 111 LYS LYS A . n 
A 1 141 THR 141 112 112 THR THR A . n 
A 1 142 GLU 142 113 113 GLU GLU A . n 
A 1 143 VAL 143 114 114 VAL VAL A . n 
A 1 144 LEU 144 115 115 LEU LEU A . n 
A 1 145 MET 145 116 116 MET MET A . n 
A 1 146 GLU 146 117 117 GLU GLU A . n 
A 1 147 ASN 147 118 118 ASN ASN A . n 
A 1 148 PHE 148 119 119 PHE PHE A . n 
A 1 149 ARG 149 120 120 ARG ARG A . n 
A 1 150 ARG 150 121 121 ARG ARG A . n 
A 1 151 ALA 151 122 122 ALA ALA A . n 
A 1 152 ILE 152 123 123 ILE ILE A . n 
A 1 153 GLY 153 124 124 GLY GLY A . n 
A 1 154 LEU 154 125 125 LEU LEU A . n 
A 1 155 ARG 155 126 126 ARG ARG A . n 
A 1 156 ILE 156 127 127 ILE ILE A . n 
A 1 157 LYS 157 128 128 LYS LYS A . n 
A 1 158 GLU 158 129 ?   ?   ?   A . n 
A 1 159 THR 159 130 ?   ?   ?   A . n 
A 1 160 LYS 160 131 ?   ?   ?   A . n 
A 1 161 GLU 161 132 ?   ?   ?   A . n 
A 1 162 VAL 162 133 ?   ?   ?   A . n 
A 1 163 TYR 163 134 ?   ?   ?   A . n 
A 1 164 GLU 164 135 ?   ?   ?   A . n 
A 1 165 GLY 165 136 ?   ?   ?   A . n 
A 1 166 GLU 166 137 ?   ?   ?   A . n 
A 1 167 VAL 167 138 ?   ?   ?   A . n 
A 1 168 THR 168 139 ?   ?   ?   A . n 
A 1 169 GLU 169 140 ?   ?   ?   A . n 
A 1 170 LEU 170 141 ?   ?   ?   A . n 
A 1 171 SER 171 142 ?   ?   ?   A . n 
A 1 172 PRO 172 143 ?   ?   ?   A . n 
A 1 173 GLU 173 144 ?   ?   ?   A . n 
A 1 174 GLU 174 145 ?   ?   ?   A . n 
A 1 175 THR 175 146 ?   ?   ?   A . n 
A 1 176 GLU 176 147 ?   ?   ?   A . n 
A 1 177 SER 177 148 ?   ?   ?   A . n 
A 1 178 LEU 178 149 ?   ?   ?   A . n 
A 1 179 THR 179 150 ?   ?   ?   A . n 
A 1 180 GLY 180 151 ?   ?   ?   A . n 
A 1 181 GLY 181 152 ?   ?   ?   A . n 
A 1 182 TYR 182 153 ?   ?   ?   A . n 
A 1 183 GLY 183 154 ?   ?   ?   A . n 
A 1 184 LYS 184 155 ?   ?   ?   A . n 
A 1 185 SER 185 156 ?   ?   ?   A . n 
A 1 186 ILE 186 157 ?   ?   ?   A . n 
A 1 187 SER 187 158 ?   ?   ?   A . n 
A 1 188 HIS 188 159 ?   ?   ?   A . n 
A 1 189 VAL 189 160 ?   ?   ?   A . n 
A 1 190 VAL 190 161 ?   ?   ?   A . n 
A 1 191 ILE 191 162 ?   ?   ?   A . n 
A 1 192 THR 192 163 ?   ?   ?   A . n 
A 1 193 LEU 193 164 ?   ?   ?   A . n 
A 1 194 LYS 194 165 ?   ?   ?   A . n 
A 1 195 THR 195 166 ?   ?   ?   A . n 
A 1 196 VAL 196 167 ?   ?   ?   A . n 
A 1 197 LYS 197 168 ?   ?   ?   A . n 
A 1 198 GLY 198 169 ?   ?   ?   A . n 
A 1 199 THR 199 170 ?   ?   ?   A . n 
A 1 200 LYS 200 171 ?   ?   ?   A . n 
A 1 201 HIS 201 172 ?   ?   ?   A . n 
A 1 202 LEU 202 173 ?   ?   ?   A . n 
A 1 203 LYS 203 174 ?   ?   ?   A . n 
A 1 204 LEU 204 175 ?   ?   ?   A . n 
A 1 205 ASP 205 176 ?   ?   ?   A . n 
A 1 206 PRO 206 177 ?   ?   ?   A . n 
A 1 207 THR 207 178 ?   ?   ?   A . n 
A 1 208 ILE 208 179 ?   ?   ?   A . n 
A 1 209 TYR 209 180 ?   ?   ?   A . n 
A 1 210 ASP 210 181 ?   ?   ?   A . n 
A 1 211 ALA 211 182 ?   ?   ?   A . n 
A 1 212 LEU 212 183 ?   ?   ?   A . n 
A 1 213 ILE 213 184 ?   ?   ?   A . n 
A 1 214 LYS 214 185 ?   ?   ?   A . n 
A 1 215 GLU 215 186 ?   ?   ?   A . n 
A 1 216 LYS 216 187 ?   ?   ?   A . n 
A 1 217 VAL 217 188 ?   ?   ?   A . n 
A 1 218 ALA 218 189 ?   ?   ?   A . n 
A 1 219 VAL 219 190 ?   ?   ?   A . n 
A 1 220 GLY 220 191 ?   ?   ?   A . n 
A 1 221 ASP 221 192 ?   ?   ?   A . n 
A 1 222 VAL 222 193 ?   ?   ?   A . n 
A 1 223 ILE 223 194 ?   ?   ?   A . n 
A 1 224 TYR 224 195 ?   ?   ?   A . n 
A 1 225 ILE 225 196 ?   ?   ?   A . n 
A 1 226 GLU 226 197 ?   ?   ?   A . n 
A 1 227 ALA 227 198 ?   ?   ?   A . n 
A 1 228 ASN 228 199 ?   ?   ?   A . n 
A 1 229 SER 229 200 ?   ?   ?   A . n 
A 1 230 GLY 230 201 ?   ?   ?   A . n 
A 1 231 ALA 231 202 ?   ?   ?   A . n 
A 1 232 VAL 232 203 ?   ?   ?   A . n 
A 1 233 LYS 233 204 ?   ?   ?   A . n 
A 1 234 ARG 234 205 ?   ?   ?   A . n 
A 1 235 VAL 235 206 ?   ?   ?   A . n 
A 1 236 GLY 236 207 ?   ?   ?   A . n 
A 1 237 ARG 237 208 ?   ?   ?   A . n 
A 1 238 SER 238 209 ?   ?   ?   A . n 
A 1 239 ASP 239 210 ?   ?   ?   A . n 
A 1 240 ALA 240 211 ?   ?   ?   A . n 
A 1 241 PHE 241 212 ?   ?   ?   A . n 
A 1 242 ALA 242 213 ?   ?   ?   A . n 
A 1 243 THR 243 214 ?   ?   ?   A . n 
A 1 244 GLU 244 215 ?   ?   ?   A . n 
A 1 245 PHE 245 216 ?   ?   ?   A . n 
A 1 246 ASP 246 217 ?   ?   ?   A . n 
A 1 247 LEU 247 218 ?   ?   ?   A . n 
A 1 248 GLU 248 219 ?   ?   ?   A . n 
A 1 249 ALA 249 220 ?   ?   ?   A . n 
A 1 250 GLU 250 221 ?   ?   ?   A . n 
A 1 251 GLU 251 222 ?   ?   ?   A . n 
A 1 252 TYR 252 223 ?   ?   ?   A . n 
A 1 253 VAL 253 224 ?   ?   ?   A . n 
A 1 254 PRO 254 225 ?   ?   ?   A . n 
A 1 255 LEU 255 226 ?   ?   ?   A . n 
A 1 256 PRO 256 227 ?   ?   ?   A . n 
A 1 257 LYS 257 228 ?   ?   ?   A . n 
A 1 258 GLY 258 229 ?   ?   ?   A . n 
A 1 259 GLU 259 230 ?   ?   ?   A . n 
A 1 260 VAL 260 231 ?   ?   ?   A . n 
A 1 261 HIS 261 232 ?   ?   ?   A . n 
A 1 262 LYS 262 233 ?   ?   ?   A . n 
A 1 263 LYS 263 234 ?   ?   ?   A . n 
A 1 264 LYS 264 235 ?   ?   ?   A . n 
A 1 265 GLU 265 236 ?   ?   ?   A . n 
A 1 266 ILE 266 237 ?   ?   ?   A . n 
A 1 267 VAL 267 238 238 VAL VAL A . n 
A 1 268 GLN 268 239 239 GLN GLN A . n 
A 1 269 ASP 269 240 240 ASP ASP A . n 
A 1 270 VAL 270 241 241 VAL VAL A . n 
A 1 271 THR 271 242 242 THR THR A . n 
A 1 272 LEU 272 243 243 LEU LEU A . n 
A 1 273 GLN 273 244 244 GLN GLN A . n 
A 1 274 ASP 274 245 245 ASP ASP A . n 
A 1 275 LEU 275 246 246 LEU LEU A . n 
A 1 276 ASP 276 247 247 ASP ASP A . n 
A 1 277 ALA 277 248 248 ALA ALA A . n 
A 1 278 ALA 278 249 249 ALA ALA A . n 
A 1 279 ASN 279 250 250 ASN ASN A . n 
A 1 280 ALA 280 251 251 ALA ALA A . n 
A 1 281 ARG 281 252 ?   ?   ?   A . n 
A 1 282 PRO 282 253 ?   ?   ?   A . n 
A 1 283 GLN 283 254 ?   ?   ?   A . n 
A 1 284 GLY 284 255 ?   ?   ?   A . n 
A 1 285 GLY 285 256 ?   ?   ?   A . n 
A 1 286 GLN 286 257 ?   ?   ?   A . n 
A 1 287 ASP 287 258 ?   ?   ?   A . n 
A 1 288 ILE 288 259 ?   ?   ?   A . n 
A 1 289 LEU 289 260 ?   ?   ?   A . n 
A 1 290 SER 290 261 ?   ?   ?   A . n 
A 1 291 LEU 291 262 ?   ?   ?   A . n 
A 1 292 MET 292 263 ?   ?   ?   A . n 
A 1 293 GLY 293 264 ?   ?   ?   A . n 
A 1 294 GLN 294 265 ?   ?   ?   A . n 
A 1 295 MET 295 266 ?   ?   ?   A . n 
A 1 296 MET 296 267 ?   ?   ?   A . n 
A 1 297 LYS 297 268 ?   ?   ?   A . n 
A 1 298 PRO 298 269 ?   ?   ?   A . n 
A 1 299 ARG 299 270 ?   ?   ?   A . n 
A 1 300 LYS 300 271 ?   ?   ?   A . n 
A 1 301 THR 301 272 ?   ?   ?   A . n 
A 1 302 GLU 302 273 ?   ?   ?   A . n 
A 1 303 ILE 303 274 ?   ?   ?   A . n 
A 1 304 THR 304 275 ?   ?   ?   A . n 
A 1 305 ASP 305 276 ?   ?   ?   A . n 
A 1 306 LYS 306 277 277 LYS LYS A . n 
A 1 307 LEU 307 278 278 LEU LEU A . n 
A 1 308 ARG 308 279 279 ARG ARG A . n 
A 1 309 GLN 309 280 280 GLN GLN A . n 
A 1 310 GLU 310 281 281 GLU GLU A . n 
A 1 311 ILE 311 282 282 ILE ILE A . n 
A 1 312 ASN 312 283 283 ASN ASN A . n 
A 1 313 LYS 313 284 284 LYS LYS A . n 
A 1 314 VAL 314 285 285 VAL VAL A . n 
A 1 315 VAL 315 286 286 VAL VAL A . n 
A 1 316 ASN 316 287 287 ASN ASN A . n 
A 1 317 ARG 317 288 288 ARG ARG A . n 
A 1 318 TYR 318 289 289 TYR TYR A . n 
A 1 319 ILE 319 290 290 ILE ILE A . n 
A 1 320 ASP 320 291 291 ASP ASP A . n 
A 1 321 GLU 321 292 292 GLU GLU A . n 
A 1 322 GLY 322 293 293 GLY GLY A . n 
A 1 323 VAL 323 294 294 VAL VAL A . n 
A 1 324 ALA 324 295 295 ALA ALA A . n 
A 1 325 GLU 325 296 296 GLU GLU A . n 
A 1 326 LEU 326 297 297 LEU LEU A . n 
A 1 327 VAL 327 298 298 VAL VAL A . n 
A 1 328 PRO 328 299 299 PRO PRO A . n 
A 1 329 GLY 329 300 300 GLY GLY A . n 
A 1 330 VAL 330 301 301 VAL VAL A . n 
A 1 331 LEU 331 302 302 LEU LEU A . n 
A 1 332 PHE 332 303 303 PHE PHE A . n 
A 1 333 ILE 333 304 304 ILE ILE A . n 
A 1 334 ASP 334 305 305 ASP ASP A . n 
A 1 335 GLU 335 306 306 GLU GLU A . n 
A 1 336 VAL 336 307 307 VAL VAL A . n 
A 1 337 HIS 337 308 308 HIS HIS A . n 
A 1 338 MET 338 309 309 MET MET A . n 
A 1 339 LEU 339 310 310 LEU LEU A . n 
A 1 340 ASP 340 311 311 ASP ASP A . n 
A 1 341 MET 341 312 312 MET MET A . n 
A 1 342 GLU 342 313 313 GLU GLU A . n 
A 1 343 CYS 343 314 314 CYS CYS A . n 
A 1 344 PHE 344 315 315 PHE PHE A . n 
A 1 345 SER 345 316 316 SER SER A . n 
A 1 346 TYR 346 317 317 TYR TYR A . n 
A 1 347 LEU 347 318 318 LEU LEU A . n 
A 1 348 ASN 348 319 319 ASN ASN A . n 
A 1 349 ARG 349 320 320 ARG ARG A . n 
A 1 350 ALA 350 321 321 ALA ALA A . n 
A 1 351 LEU 351 322 322 LEU LEU A . n 
A 1 352 GLU 352 323 323 GLU GLU A . n 
A 1 353 SER 353 324 324 SER SER A . n 
A 1 354 SER 354 325 325 SER SER A . n 
A 1 355 LEU 355 326 326 LEU LEU A . n 
A 1 356 SER 356 327 327 SER SER A . n 
A 1 357 PRO 357 328 328 PRO PRO A . n 
A 1 358 ILE 358 329 329 ILE ILE A . n 
A 1 359 VAL 359 330 330 VAL VAL A . n 
A 1 360 ILE 360 331 331 ILE ILE A . n 
A 1 361 PHE 361 332 332 PHE PHE A . n 
A 1 362 ALA 362 333 333 ALA ALA A . n 
A 1 363 THR 363 334 334 THR THR A . n 
A 1 364 ASN 364 335 335 ASN ASN A . n 
A 1 365 ARG 365 336 336 ARG ARG A . n 
A 1 366 GLY 366 337 337 GLY GLY A . n 
A 1 367 VAL 367 338 338 VAL VAL A . n 
A 1 368 CYS 368 339 339 CYS CYS A . n 
A 1 369 ASN 369 340 340 ASN ASN A . n 
A 1 370 VAL 370 341 341 VAL VAL A . n 
A 1 371 ARG 371 342 342 ARG ARG A . n 
A 1 372 GLY 372 343 343 GLY GLY A . n 
A 1 373 THR 373 344 344 THR THR A . n 
A 1 374 ASP 374 345 345 ASP ASP A . n 
A 1 375 MET 375 346 346 MET MET A . n 
A 1 376 PRO 376 347 347 PRO PRO A . n 
A 1 377 SER 377 348 348 SER SER A . n 
A 1 378 PRO 378 349 349 PRO PRO A . n 
A 1 379 HIS 379 350 350 HIS HIS A . n 
A 1 380 GLY 380 351 351 GLY GLY A . n 
A 1 381 VAL 381 352 352 VAL VAL A . n 
A 1 382 PRO 382 353 353 PRO PRO A . n 
A 1 383 ILE 383 354 354 ILE ILE A . n 
A 1 384 ASP 384 355 355 ASP ASP A . n 
A 1 385 LEU 385 356 356 LEU LEU A . n 
A 1 386 LEU 386 357 357 LEU LEU A . n 
A 1 387 ASP 387 358 358 ASP ASP A . n 
A 1 388 ARG 388 359 359 ARG ARG A . n 
A 1 389 LEU 389 360 360 LEU LEU A . n 
A 1 390 VAL 390 361 361 VAL VAL A . n 
A 1 391 ILE 391 362 362 ILE ILE A . n 
A 1 392 ILE 392 363 363 ILE ILE A . n 
A 1 393 ARG 393 364 364 ARG ARG A . n 
A 1 394 THR 394 365 365 THR THR A . n 
A 1 395 GLN 395 366 366 GLN GLN A . n 
A 1 396 ILE 396 367 367 ILE ILE A . n 
A 1 397 TYR 397 368 368 TYR TYR A . n 
A 1 398 ASP 398 369 369 ASP ASP A . n 
A 1 399 PRO 399 370 370 PRO PRO A . n 
A 1 400 SER 400 371 371 SER SER A . n 
A 1 401 GLU 401 372 372 GLU GLU A . n 
A 1 402 MET 402 373 373 MET MET A . n 
A 1 403 ILE 403 374 374 ILE ILE A . n 
A 1 404 GLN 404 375 375 GLN GLN A . n 
A 1 405 ILE 405 376 376 ILE ILE A . n 
A 1 406 ILE 406 377 377 ILE ILE A . n 
A 1 407 ALA 407 378 378 ALA ALA A . n 
A 1 408 ILE 408 379 379 ILE ILE A . n 
A 1 409 ARG 409 380 380 ARG ARG A . n 
A 1 410 ALA 410 381 381 ALA ALA A . n 
A 1 411 GLN 411 382 382 GLN GLN A . n 
A 1 412 VAL 412 383 383 VAL VAL A . n 
A 1 413 GLU 413 384 384 GLU GLU A . n 
A 1 414 GLU 414 385 385 GLU GLU A . n 
A 1 415 LEU 415 386 386 LEU LEU A . n 
A 1 416 THR 416 387 387 THR THR A . n 
A 1 417 VAL 417 388 388 VAL VAL A . n 
A 1 418 ASP 418 389 389 ASP ASP A . n 
A 1 419 GLU 419 390 390 GLU GLU A . n 
A 1 420 GLU 420 391 391 GLU GLU A . n 
A 1 421 CYS 421 392 392 CYS CYS A . n 
A 1 422 LEU 422 393 393 LEU LEU A . n 
A 1 423 VAL 423 394 394 VAL VAL A . n 
A 1 424 LEU 424 395 395 LEU LEU A . n 
A 1 425 LEU 425 396 396 LEU LEU A . n 
A 1 426 GLY 426 397 397 GLY GLY A . n 
A 1 427 GLU 427 398 398 GLU GLU A . n 
A 1 428 ILE 428 399 399 ILE ILE A . n 
A 1 429 GLY 429 400 400 GLY GLY A . n 
A 1 430 GLN 430 401 401 GLN GLN A . n 
A 1 431 ARG 431 402 402 ARG ARG A . n 
A 1 432 THR 432 403 403 THR THR A . n 
A 1 433 SER 433 404 404 SER SER A . n 
A 1 434 LEU 434 405 405 LEU LEU A . n 
A 1 435 ARG 435 406 406 ARG ARG A . n 
A 1 436 HIS 436 407 407 HIS HIS A . n 
A 1 437 ALA 437 408 408 ALA ALA A . n 
A 1 438 VAL 438 409 409 VAL VAL A . n 
A 1 439 GLN 439 410 410 GLN GLN A . n 
A 1 440 LEU 440 411 411 LEU LEU A . n 
A 1 441 LEU 441 412 412 LEU LEU A . n 
A 1 442 SER 442 413 413 SER SER A . n 
A 1 443 PRO 443 414 414 PRO PRO A . n 
A 1 444 ALA 444 415 415 ALA ALA A . n 
A 1 445 SER 445 416 416 SER SER A . n 
A 1 446 ILE 446 417 417 ILE ILE A . n 
A 1 447 VAL 447 418 418 VAL VAL A . n 
A 1 448 ALA 448 419 419 ALA ALA A . n 
A 1 449 LYS 449 420 420 LYS LYS A . n 
A 1 450 MET 450 421 421 MET MET A . n 
A 1 451 ASN 451 422 422 ASN ASN A . n 
A 1 452 GLY 452 423 423 GLY GLY A . n 
A 1 453 ARG 453 424 424 ARG ARG A . n 
A 1 454 ASP 454 425 425 ASP ASP A . n 
A 1 455 ASN 455 426 426 ASN ASN A . n 
A 1 456 ILE 456 427 427 ILE ILE A . n 
A 1 457 CYS 457 428 428 CYS CYS A . n 
A 1 458 LYS 458 429 429 LYS LYS A . n 
A 1 459 ALA 459 430 430 ALA ALA A . n 
A 1 460 ASP 460 431 431 ASP ASP A . n 
A 1 461 ILE 461 432 432 ILE ILE A . n 
A 1 462 GLU 462 433 433 GLU GLU A . n 
A 1 463 GLU 463 434 434 GLU GLU A . n 
A 1 464 VAL 464 435 435 VAL VAL A . n 
A 1 465 THR 465 436 436 THR THR A . n 
A 1 466 SER 466 437 437 SER SER A . n 
A 1 467 LEU 467 438 438 LEU LEU A . n 
A 1 468 TYR 468 439 439 TYR TYR A . n 
A 1 469 LEU 469 440 440 LEU LEU A . n 
A 1 470 ASP 470 441 441 ASP ASP A . n 
A 1 471 ALA 471 442 442 ALA ALA A . n 
A 1 472 LYS 472 443 443 LYS LYS A . n 
A 1 473 SER 473 444 444 SER SER A . n 
A 1 474 SER 474 445 445 SER SER A . n 
A 1 475 ALA 475 446 446 ALA ALA A . n 
A 1 476 LYS 476 447 447 LYS LYS A . n 
A 1 477 LEU 477 448 448 LEU LEU A . n 
A 1 478 LEU 478 449 449 LEU LEU A . n 
A 1 479 HIS 479 450 450 HIS HIS A . n 
A 1 480 GLU 480 451 451 GLU GLU A . n 
A 1 481 GLN 481 452 452 GLN GLN A . n 
A 1 482 GLN 482 453 ?   ?   ?   A . n 
A 1 483 GLU 483 454 ?   ?   ?   A . n 
A 1 484 LYS 484 455 ?   ?   ?   A . n 
A 1 485 TYR 485 456 ?   ?   ?   A . n 
A 1 486 ILE 486 457 ?   ?   ?   A . n 
A 1 487 SER 487 458 ?   ?   ?   A . n 
B 2 1   MET 1   -17 ?   ?   ?   D . n 
B 2 2   ALA 2   -16 ?   ?   ?   D . n 
B 2 3   ASP 3   -15 ?   ?   ?   D . n 
B 2 4   LEU 4   -14 ?   ?   ?   D . n 
B 2 5   ASN 5   -13 ?   ?   ?   D . n 
B 2 6   TRP 6   -12 ?   ?   ?   D . n 
B 2 7   ILE 7   -11 ?   ?   ?   D . n 
B 2 8   SER 8   -10 ?   ?   ?   D . n 
B 2 9   ALA 9   -9  ?   ?   ?   D . n 
B 2 10  GLY 10  -8  ?   ?   ?   D . n 
B 2 11  HIS 11  -7  ?   ?   ?   D . n 
B 2 12  ALA 12  -6  ?   ?   ?   D . n 
B 2 13  ILE 13  -5  ?   ?   ?   D . n 
B 2 14  ALA 14  -4  ?   ?   ?   D . n 
B 2 15  ASP 15  -3  ?   ?   ?   D . n 
B 2 16  VAL 16  -2  ?   ?   ?   D . n 
B 2 17  GLY 17  -1  ?   ?   ?   D . n 
B 2 18  THR 18  0   ?   ?   ?   D . n 
B 2 19  MET 19  1   ?   ?   ?   D . n 
B 2 20  ALA 20  2   ?   ?   ?   D . n 
B 2 21  GLU 21  3   ?   ?   ?   D . n 
B 2 22  LEU 22  4   ?   ?   ?   D . n 
B 2 23  LYS 23  5   ?   ?   ?   D . n 
B 2 24  LEU 24  6   ?   ?   ?   D . n 
B 2 25  SER 25  7   ?   ?   ?   D . n 
B 2 26  GLU 26  8   ?   ?   ?   D . n 
B 2 27  SER 27  9   ?   ?   ?   D . n 
B 2 28  ARG 28  10  ?   ?   ?   D . n 
B 2 29  ASP 29  11  ?   ?   ?   D . n 
B 2 30  LEU 30  12  ?   ?   ?   D . n 
B 2 31  THR 31  13  ?   ?   ?   D . n 
B 2 32  ARG 32  14  ?   ?   ?   D . n 
B 2 33  VAL 33  15  ?   ?   ?   D . n 
B 2 34  GLU 34  16  ?   ?   ?   D . n 
B 2 35  ARG 35  17  ?   ?   ?   D . n 
B 2 36  ILE 36  18  ?   ?   ?   D . n 
B 2 37  GLY 37  19  ?   ?   ?   D . n 
B 2 38  ALA 38  20  ?   ?   ?   D . n 
B 2 39  HIS 39  21  ?   ?   ?   D . n 
B 2 40  SER 40  22  ?   ?   ?   D . n 
B 2 41  HIS 41  23  ?   ?   ?   D . n 
B 2 42  ILE 42  24  ?   ?   ?   D . n 
B 2 43  ARG 43  25  ?   ?   ?   D . n 
B 2 44  GLY 44  26  ?   ?   ?   D . n 
B 2 45  LEU 45  27  ?   ?   ?   D . n 
B 2 46  GLY 46  28  ?   ?   ?   D . n 
B 2 47  LEU 47  29  ?   ?   ?   D . n 
B 2 48  ASP 48  30  ?   ?   ?   D . n 
B 2 49  SER 49  31  ?   ?   ?   D . n 
B 2 50  ALA 50  32  ?   ?   ?   D . n 
B 2 51  LEU 51  33  ?   ?   ?   D . n 
B 2 52  GLU 52  34  ?   ?   ?   D . n 
B 2 53  PRO 53  35  ?   ?   ?   D . n 
B 2 54  ARG 54  36  ?   ?   ?   D . n 
B 2 55  ALA 55  37  ?   ?   ?   D . n 
B 2 56  VAL 56  38  ?   ?   ?   D . n 
B 2 57  SER 57  39  ?   ?   ?   D . n 
B 2 58  GLU 58  40  ?   ?   ?   D . n 
B 2 59  GLY 59  41  ?   ?   ?   D . n 
B 2 60  MET 60  42  ?   ?   ?   D . n 
B 2 61  VAL 61  43  ?   ?   ?   D . n 
B 2 62  GLY 62  44  ?   ?   ?   D . n 
B 2 63  GLN 63  45  45  GLN GLN D . n 
B 2 64  VAL 64  46  46  VAL VAL D . n 
B 2 65  LYS 65  47  47  LYS LYS D . n 
B 2 66  ALA 66  48  48  ALA ALA D . n 
B 2 67  ARG 67  49  49  ARG ARG D . n 
B 2 68  LYS 68  50  50  LYS LYS D . n 
B 2 69  ALA 69  51  51  ALA ALA D . n 
B 2 70  ALA 70  52  52  ALA ALA D . n 
B 2 71  GLY 71  53  53  GLY GLY D . n 
B 2 72  VAL 72  54  54  VAL VAL D . n 
B 2 73  ILE 73  55  55  ILE ILE D . n 
B 2 74  LEU 74  56  56  LEU LEU D . n 
B 2 75  GLN 75  57  57  GLN GLN D . n 
B 2 76  MET 76  58  58  MET MET D . n 
B 2 77  ILE 77  59  59  ILE ILE D . n 
B 2 78  ARG 78  60  60  ARG ARG D . n 
B 2 79  GLU 79  61  61  GLU GLU D . n 
B 2 80  GLY 80  62  62  GLY GLY D . n 
B 2 81  LYS 81  63  63  LYS LYS D . n 
B 2 82  ILE 82  64  64  ILE ILE D . n 
B 2 83  ALA 83  65  65  ALA ALA D . n 
B 2 84  GLY 84  66  66  GLY GLY D . n 
B 2 85  ARG 85  67  67  ARG ARG D . n 
B 2 86  ALA 86  68  68  ALA ALA D . n 
B 2 87  ILE 87  69  69  ILE ILE D . n 
B 2 88  LEU 88  70  70  LEU LEU D . n 
B 2 89  ILE 89  71  71  ILE ILE D . n 
B 2 90  ALA 90  72  72  ALA ALA D . n 
B 2 91  GLY 91  73  73  GLY GLY D . n 
B 2 92  GLN 92  74  74  GLN GLN D . n 
B 2 93  PRO 93  75  75  PRO PRO D . n 
B 2 94  GLY 94  76  76  GLY GLY D . n 
B 2 95  THR 95  77  77  THR THR D . n 
B 2 96  GLY 96  78  78  GLY GLY D . n 
B 2 97  LYS 97  79  79  LYS LYS D . n 
B 2 98  THR 98  80  80  THR THR D . n 
B 2 99  ALA 99  81  81  ALA ALA D . n 
B 2 100 ILE 100 82  82  ILE ILE D . n 
B 2 101 ALA 101 83  83  ALA ALA D . n 
B 2 102 MET 102 84  84  MET MET D . n 
B 2 103 GLY 103 85  85  GLY GLY D . n 
B 2 104 MET 104 86  86  MET MET D . n 
B 2 105 ALA 105 87  87  ALA ALA D . n 
B 2 106 LYS 106 88  88  LYS LYS D . n 
B 2 107 SER 107 89  89  SER SER D . n 
B 2 108 LEU 108 90  90  LEU LEU D . n 
B 2 109 GLY 109 91  91  GLY GLY D . n 
B 2 110 LEU 110 92  92  LEU LEU D . n 
B 2 111 GLU 111 93  93  GLU GLU D . n 
B 2 112 THR 112 94  94  THR THR D . n 
B 2 113 PRO 113 95  95  PRO PRO D . n 
B 2 114 PHE 114 96  96  PHE PHE D . n 
B 2 115 ALA 115 97  97  ALA ALA D . n 
B 2 116 MET 116 98  98  MET MET D . n 
B 2 117 ILE 117 99  99  ILE ILE D . n 
B 2 118 ALA 118 100 100 ALA ALA D . n 
B 2 119 GLY 119 101 101 GLY GLY D . n 
B 2 120 SER 120 102 102 SER SER D . n 
B 2 121 GLU 121 103 103 GLU GLU D . n 
B 2 122 ILE 122 104 104 ILE ILE D . n 
B 2 123 PHE 123 105 105 PHE PHE D . n 
B 2 124 SER 124 106 106 SER SER D . n 
B 2 125 LEU 125 107 107 LEU LEU D . n 
B 2 126 GLU 126 108 108 GLU GLU D . n 
B 2 127 MET 127 109 109 MET MET D . n 
B 2 128 SER 128 110 110 SER SER D . n 
B 2 129 LYS 129 111 111 LYS LYS D . n 
B 2 130 THR 130 112 112 THR THR D . n 
B 2 131 GLU 131 113 113 GLU GLU D . n 
B 2 132 ALA 132 114 114 ALA ALA D . n 
B 2 133 LEU 133 115 115 LEU LEU D . n 
B 2 134 THR 134 116 116 THR THR D . n 
B 2 135 GLN 135 117 117 GLN GLN D . n 
B 2 136 SER 136 118 118 SER SER D . n 
B 2 137 PHE 137 119 119 PHE PHE D . n 
B 2 138 ARG 138 120 120 ARG ARG D . n 
B 2 139 LYS 139 121 121 LYS LYS D . n 
B 2 140 ALA 140 122 122 ALA ALA D . n 
B 2 141 ILE 141 123 123 ILE ILE D . n 
B 2 142 GLY 142 124 124 GLY GLY D . n 
B 2 143 VAL 143 125 125 VAL VAL D . n 
B 2 144 ARG 144 126 126 ARG ARG D . n 
B 2 145 ILE 145 127 ?   ?   ?   D . n 
B 2 146 LYS 146 128 ?   ?   ?   D . n 
B 2 147 GLU 147 129 ?   ?   ?   D . n 
B 2 148 GLU 148 130 ?   ?   ?   D . n 
B 2 149 THR 149 131 ?   ?   ?   D . n 
B 2 150 GLU 150 132 ?   ?   ?   D . n 
B 2 151 VAL 151 133 ?   ?   ?   D . n 
B 2 152 ILE 152 134 ?   ?   ?   D . n 
B 2 153 GLU 153 135 ?   ?   ?   D . n 
B 2 154 GLY 154 136 ?   ?   ?   D . n 
B 2 155 GLU 155 137 ?   ?   ?   D . n 
B 2 156 VAL 156 138 ?   ?   ?   D . n 
B 2 157 VAL 157 139 ?   ?   ?   D . n 
B 2 158 GLU 158 140 ?   ?   ?   D . n 
B 2 159 VAL 159 141 ?   ?   ?   D . n 
B 2 160 GLN 160 142 ?   ?   ?   D . n 
B 2 161 ILE 161 143 ?   ?   ?   D . n 
B 2 162 ASP 162 144 ?   ?   ?   D . n 
B 2 163 ARG 163 145 ?   ?   ?   D . n 
B 2 164 PRO 164 146 ?   ?   ?   D . n 
B 2 165 ALA 165 147 ?   ?   ?   D . n 
B 2 166 SER 166 148 ?   ?   ?   D . n 
B 2 167 SER 167 149 ?   ?   ?   D . n 
B 2 168 GLY 168 150 ?   ?   ?   D . n 
B 2 169 VAL 169 151 ?   ?   ?   D . n 
B 2 170 ALA 170 152 ?   ?   ?   D . n 
B 2 171 SER 171 153 ?   ?   ?   D . n 
B 2 172 LYS 172 154 ?   ?   ?   D . n 
B 2 173 SER 173 155 ?   ?   ?   D . n 
B 2 174 GLY 174 156 ?   ?   ?   D . n 
B 2 175 LYS 175 157 ?   ?   ?   D . n 
B 2 176 MET 176 158 ?   ?   ?   D . n 
B 2 177 THR 177 159 ?   ?   ?   D . n 
B 2 178 MET 178 160 ?   ?   ?   D . n 
B 2 179 LYS 179 161 ?   ?   ?   D . n 
B 2 180 THR 180 162 ?   ?   ?   D . n 
B 2 181 THR 181 163 ?   ?   ?   D . n 
B 2 182 ASP 182 164 ?   ?   ?   D . n 
B 2 183 MET 183 165 ?   ?   ?   D . n 
B 2 184 GLU 184 166 ?   ?   ?   D . n 
B 2 185 THR 185 167 ?   ?   ?   D . n 
B 2 186 VAL 186 168 ?   ?   ?   D . n 
B 2 187 TYR 187 169 ?   ?   ?   D . n 
B 2 188 ASP 188 170 ?   ?   ?   D . n 
B 2 189 MET 189 171 ?   ?   ?   D . n 
B 2 190 GLY 190 172 ?   ?   ?   D . n 
B 2 191 ALA 191 173 ?   ?   ?   D . n 
B 2 192 LYS 192 174 ?   ?   ?   D . n 
B 2 193 MET 193 175 ?   ?   ?   D . n 
B 2 194 ILE 194 176 ?   ?   ?   D . n 
B 2 195 GLU 195 177 ?   ?   ?   D . n 
B 2 196 ALA 196 178 ?   ?   ?   D . n 
B 2 197 LEU 197 179 ?   ?   ?   D . n 
B 2 198 ASN 198 180 ?   ?   ?   D . n 
B 2 199 LYS 199 181 ?   ?   ?   D . n 
B 2 200 GLU 200 182 ?   ?   ?   D . n 
B 2 201 LYS 201 183 ?   ?   ?   D . n 
B 2 202 VAL 202 184 ?   ?   ?   D . n 
B 2 203 GLN 203 185 ?   ?   ?   D . n 
B 2 204 SER 204 186 ?   ?   ?   D . n 
B 2 205 GLY 205 187 ?   ?   ?   D . n 
B 2 206 ASP 206 188 ?   ?   ?   D . n 
B 2 207 VAL 207 189 ?   ?   ?   D . n 
B 2 208 ILE 208 190 ?   ?   ?   D . n 
B 2 209 ALA 209 191 ?   ?   ?   D . n 
B 2 210 ILE 210 192 ?   ?   ?   D . n 
B 2 211 ASP 211 193 ?   ?   ?   D . n 
B 2 212 LYS 212 194 ?   ?   ?   D . n 
B 2 213 ALA 213 195 ?   ?   ?   D . n 
B 2 214 THR 214 196 ?   ?   ?   D . n 
B 2 215 GLY 215 197 ?   ?   ?   D . n 
B 2 216 LYS 216 198 ?   ?   ?   D . n 
B 2 217 ILE 217 199 ?   ?   ?   D . n 
B 2 218 THR 218 200 ?   ?   ?   D . n 
B 2 219 LYS 219 201 ?   ?   ?   D . n 
B 2 220 LEU 220 202 ?   ?   ?   D . n 
B 2 221 GLY 221 203 ?   ?   ?   D . n 
B 2 222 ARG 222 204 ?   ?   ?   D . n 
B 2 223 SER 223 205 ?   ?   ?   D . n 
B 2 224 PHE 224 206 ?   ?   ?   D . n 
B 2 225 SER 225 207 ?   ?   ?   D . n 
B 2 226 ARG 226 208 ?   ?   ?   D . n 
B 2 227 SER 227 209 ?   ?   ?   D . n 
B 2 228 ARG 228 210 ?   ?   ?   D . n 
B 2 229 ASP 229 211 ?   ?   ?   D . n 
B 2 230 TYR 230 212 ?   ?   ?   D . n 
B 2 231 ASP 231 213 ?   ?   ?   D . n 
B 2 232 ALA 232 214 ?   ?   ?   D . n 
B 2 233 MET 233 215 ?   ?   ?   D . n 
B 2 234 GLY 234 216 ?   ?   ?   D . n 
B 2 235 ALA 235 217 ?   ?   ?   D . n 
B 2 236 GLN 236 218 ?   ?   ?   D . n 
B 2 237 THR 237 219 ?   ?   ?   D . n 
B 2 238 LYS 238 220 ?   ?   ?   D . n 
B 2 239 PHE 239 221 ?   ?   ?   D . n 
B 2 240 VAL 240 222 ?   ?   ?   D . n 
B 2 241 GLN 241 223 ?   ?   ?   D . n 
B 2 242 CYS 242 224 ?   ?   ?   D . n 
B 2 243 PRO 243 225 ?   ?   ?   D . n 
B 2 244 GLU 244 226 ?   ?   ?   D . n 
B 2 245 GLY 245 227 ?   ?   ?   D . n 
B 2 246 GLU 246 228 ?   ?   ?   D . n 
B 2 247 LEU 247 229 ?   ?   ?   D . n 
B 2 248 GLN 248 230 ?   ?   ?   D . n 
B 2 249 LYS 249 231 ?   ?   ?   D . n 
B 2 250 ARG 250 232 ?   ?   ?   D . n 
B 2 251 LYS 251 233 ?   ?   ?   D . n 
B 2 252 GLU 252 234 ?   ?   ?   D . n 
B 2 253 VAL 253 235 ?   ?   ?   D . n 
B 2 254 VAL 254 236 ?   ?   ?   D . n 
B 2 255 HIS 255 237 ?   ?   ?   D . n 
B 2 256 CYS 256 238 238 CYS CYS D . n 
B 2 257 VAL 257 239 239 VAL VAL D . n 
B 2 258 THR 258 240 240 THR THR D . n 
B 2 259 LEU 259 241 241 LEU LEU D . n 
B 2 260 HIS 260 242 242 HIS HIS D . n 
B 2 261 GLU 261 243 243 GLU GLU D . n 
B 2 262 ILE 262 244 244 ILE ILE D . n 
B 2 263 ASP 263 245 245 ASP ASP D . n 
B 2 264 VAL 264 246 246 VAL VAL D . n 
B 2 265 ILE 265 247 247 ILE ILE D . n 
B 2 266 ASN 266 248 248 ASN ASN D . n 
B 2 267 SER 267 249 249 SER SER D . n 
B 2 268 ARG 268 250 ?   ?   ?   D . n 
B 2 269 THR 269 251 ?   ?   ?   D . n 
B 2 270 GLN 270 252 ?   ?   ?   D . n 
B 2 271 GLY 271 253 ?   ?   ?   D . n 
B 2 272 PHE 272 254 ?   ?   ?   D . n 
B 2 273 LEU 273 255 ?   ?   ?   D . n 
B 2 274 ALA 274 256 ?   ?   ?   D . n 
B 2 275 LEU 275 257 ?   ?   ?   D . n 
B 2 276 PHE 276 258 ?   ?   ?   D . n 
B 2 277 THR 277 259 ?   ?   ?   D . n 
B 2 278 GLY 278 260 ?   ?   ?   D . n 
B 2 279 ASP 279 261 ?   ?   ?   D . n 
B 2 280 THR 280 262 262 THR THR D . n 
B 2 281 GLY 281 263 263 GLY GLY D . n 
B 2 282 GLU 282 264 264 GLU GLU D . n 
B 2 283 ILE 283 265 265 ILE ILE D . n 
B 2 284 ARG 284 266 266 ARG ARG D . n 
B 2 285 SER 285 267 267 SER SER D . n 
B 2 286 GLU 286 268 268 GLU GLU D . n 
B 2 287 VAL 287 269 269 VAL VAL D . n 
B 2 288 ARG 288 270 270 ARG ARG D . n 
B 2 289 GLU 289 271 271 GLU GLU D . n 
B 2 290 GLN 290 272 272 GLN GLN D . n 
B 2 291 ILE 291 273 273 ILE ILE D . n 
B 2 292 ASP 292 274 274 ASP ASP D . n 
B 2 293 THR 293 275 275 THR THR D . n 
B 2 294 LYS 294 276 276 LYS LYS D . n 
B 2 295 VAL 295 277 277 VAL VAL D . n 
B 2 296 ALA 296 278 278 ALA ALA D . n 
B 2 297 GLU 297 279 279 GLU GLU D . n 
B 2 298 TRP 298 280 280 TRP TRP D . n 
B 2 299 ARG 299 281 281 ARG ARG D . n 
B 2 300 GLU 300 282 282 GLU GLU D . n 
B 2 301 GLU 301 283 283 GLU GLU D . n 
B 2 302 GLY 302 284 284 GLY GLY D . n 
B 2 303 LYS 303 285 285 LYS LYS D . n 
B 2 304 ALA 304 286 286 ALA ALA D . n 
B 2 305 GLU 305 287 287 GLU GLU D . n 
B 2 306 ILE 306 288 288 ILE ILE D . n 
B 2 307 VAL 307 289 289 VAL VAL D . n 
B 2 308 PRO 308 290 290 PRO PRO D . n 
B 2 309 GLY 309 291 291 GLY GLY D . n 
B 2 310 VAL 310 292 292 VAL VAL D . n 
B 2 311 LEU 311 293 293 LEU LEU D . n 
B 2 312 PHE 312 294 294 PHE PHE D . n 
B 2 313 ILE 313 295 295 ILE ILE D . n 
B 2 314 ASP 314 296 296 ASP ASP D . n 
B 2 315 GLU 315 297 297 GLU GLU D . n 
B 2 316 VAL 316 298 298 VAL VAL D . n 
B 2 317 HIS 317 299 299 HIS HIS D . n 
B 2 318 MET 318 300 300 MET MET D . n 
B 2 319 LEU 319 301 301 LEU LEU D . n 
B 2 320 ASP 320 302 302 ASP ASP D . n 
B 2 321 ILE 321 303 303 ILE ILE D . n 
B 2 322 GLU 322 304 304 GLU GLU D . n 
B 2 323 CYS 323 305 305 CYS CYS D . n 
B 2 324 PHE 324 306 306 PHE PHE D . n 
B 2 325 SER 325 307 307 SER SER D . n 
B 2 326 PHE 326 308 308 PHE PHE D . n 
B 2 327 LEU 327 309 309 LEU LEU D . n 
B 2 328 ASN 328 310 310 ASN ASN D . n 
B 2 329 ARG 329 311 311 ARG ARG D . n 
B 2 330 ALA 330 312 312 ALA ALA D . n 
B 2 331 LEU 331 313 313 LEU LEU D . n 
B 2 332 GLU 332 314 314 GLU GLU D . n 
B 2 333 ASN 333 315 315 ASN ASN D . n 
B 2 334 GLU 334 316 316 GLU GLU D . n 
B 2 335 MET 335 317 317 MET MET D . n 
B 2 336 SER 336 318 318 SER SER D . n 
B 2 337 PRO 337 319 319 PRO PRO D . n 
B 2 338 ILE 338 320 320 ILE ILE D . n 
B 2 339 LEU 339 321 321 LEU LEU D . n 
B 2 340 VAL 340 322 322 VAL VAL D . n 
B 2 341 VAL 341 323 323 VAL VAL D . n 
B 2 342 ALA 342 324 324 ALA ALA D . n 
B 2 343 THR 343 325 325 THR THR D . n 
B 2 344 ASN 344 326 326 ASN ASN D . n 
B 2 345 ARG 345 327 327 ARG ARG D . n 
B 2 346 GLY 346 328 328 GLY GLY D . n 
B 2 347 VAL 347 329 329 VAL VAL D . n 
B 2 348 THR 348 330 330 THR THR D . n 
B 2 349 THR 349 331 331 THR THR D . n 
B 2 350 ILE 350 332 332 ILE ILE D . n 
B 2 351 ARG 351 333 333 ARG ARG D . n 
B 2 352 GLY 352 334 334 GLY GLY D . n 
B 2 353 THR 353 335 335 THR THR D . n 
B 2 354 ASN 354 336 336 ASN ASN D . n 
B 2 355 GLN 355 337 337 GLN GLN D . n 
B 2 356 LYS 356 338 338 LYS LYS D . n 
B 2 357 SER 357 339 339 SER SER D . n 
B 2 358 PRO 358 340 340 PRO PRO D . n 
B 2 359 HIS 359 341 341 HIS HIS D . n 
B 2 360 GLY 360 342 342 GLY GLY D . n 
B 2 361 ILE 361 343 343 ILE ILE D . n 
B 2 362 PRO 362 344 344 PRO PRO D . n 
B 2 363 ILE 363 345 345 ILE ILE D . n 
B 2 364 ASP 364 346 346 ASP ASP D . n 
B 2 365 LEU 365 347 347 LEU LEU D . n 
B 2 366 LEU 366 348 348 LEU LEU D . n 
B 2 367 ASP 367 349 349 ASP ASP D . n 
B 2 368 ARG 368 350 350 ARG ARG D . n 
B 2 369 LEU 369 351 351 LEU LEU D . n 
B 2 370 LEU 370 352 352 LEU LEU D . n 
B 2 371 ILE 371 353 353 ILE ILE D . n 
B 2 372 ILE 372 354 354 ILE ILE D . n 
B 2 373 THR 373 355 355 THR THR D . n 
B 2 374 THR 374 356 356 THR THR D . n 
B 2 375 GLN 375 357 357 GLN GLN D . n 
B 2 376 PRO 376 358 358 PRO PRO D . n 
B 2 377 TYR 377 359 359 TYR TYR D . n 
B 2 378 THR 378 360 360 THR THR D . n 
B 2 379 ASP 379 361 361 ASP ASP D . n 
B 2 380 ASP 380 362 362 ASP ASP D . n 
B 2 381 ASP 381 363 363 ASP ASP D . n 
B 2 382 ILE 382 364 364 ILE ILE D . n 
B 2 383 ARG 383 365 365 ARG ARG D . n 
B 2 384 LYS 384 366 366 LYS LYS D . n 
B 2 385 ILE 385 367 367 ILE ILE D . n 
B 2 386 LEU 386 368 368 LEU LEU D . n 
B 2 387 GLU 387 369 369 GLU GLU D . n 
B 2 388 ILE 388 370 370 ILE ILE D . n 
B 2 389 ARG 389 371 371 ARG ARG D . n 
B 2 390 CYS 390 372 372 CYS CYS D . n 
B 2 391 GLN 391 373 373 GLN GLN D . n 
B 2 392 GLU 392 374 374 GLU GLU D . n 
B 2 393 GLU 393 375 375 GLU GLU D . n 
B 2 394 ASP 394 376 376 ASP ASP D . n 
B 2 395 VAL 395 377 377 VAL VAL D . n 
B 2 396 GLU 396 378 378 GLU GLU D . n 
B 2 397 MET 397 379 379 MET MET D . n 
B 2 398 ASN 398 380 380 ASN ASN D . n 
B 2 399 GLU 399 381 381 GLU GLU D . n 
B 2 400 GLU 400 382 382 GLU GLU D . n 
B 2 401 ALA 401 383 383 ALA ALA D . n 
B 2 402 LYS 402 384 384 LYS LYS D . n 
B 2 403 GLN 403 385 385 GLN GLN D . n 
B 2 404 LEU 404 386 386 LEU LEU D . n 
B 2 405 LEU 405 387 387 LEU LEU D . n 
B 2 406 THR 406 388 388 THR THR D . n 
B 2 407 LEU 407 389 389 LEU LEU D . n 
B 2 408 ILE 408 390 390 ILE ILE D . n 
B 2 409 GLY 409 391 391 GLY GLY D . n 
B 2 410 ARG 410 392 392 ARG ARG D . n 
B 2 411 ASP 411 393 393 ASP ASP D . n 
B 2 412 THR 412 394 394 THR THR D . n 
B 2 413 SER 413 395 395 SER SER D . n 
B 2 414 LEU 414 396 396 LEU LEU D . n 
B 2 415 ARG 415 397 397 ARG ARG D . n 
B 2 416 TYR 416 398 398 TYR TYR D . n 
B 2 417 ALA 417 399 399 ALA ALA D . n 
B 2 418 ILE 418 400 400 ILE ILE D . n 
B 2 419 HIS 419 401 401 HIS HIS D . n 
B 2 420 LEU 420 402 402 LEU LEU D . n 
B 2 421 ILE 421 403 403 ILE ILE D . n 
B 2 422 THR 422 404 404 THR THR D . n 
B 2 423 ALA 423 405 405 ALA ALA D . n 
B 2 424 ALA 424 406 406 ALA ALA D . n 
B 2 425 ALA 425 407 407 ALA ALA D . n 
B 2 426 LEU 426 408 408 LEU LEU D . n 
B 2 427 SER 427 409 409 SER SER D . n 
B 2 428 CYS 428 410 410 CYS CYS D . n 
B 2 429 GLN 429 411 411 GLN GLN D . n 
B 2 430 LYS 430 412 412 LYS LYS D . n 
B 2 431 ARG 431 413 413 ARG ARG D . n 
B 2 432 LYS 432 414 414 LYS LYS D . n 
B 2 433 GLY 433 415 415 GLY GLY D . n 
B 2 434 LYS 434 416 416 LYS LYS D . n 
B 2 435 VAL 435 417 417 VAL VAL D . n 
B 2 436 VAL 436 418 418 VAL VAL D . n 
B 2 437 GLU 437 419 419 GLU GLU D . n 
B 2 438 VAL 438 420 420 VAL VAL D . n 
B 2 439 GLU 439 421 421 GLU GLU D . n 
B 2 440 ASP 440 422 422 ASP ASP D . n 
B 2 441 ILE 441 423 423 ILE ILE D . n 
B 2 442 GLN 442 424 424 GLN GLN D . n 
B 2 443 ARG 443 425 425 ARG ARG D . n 
B 2 444 VAL 444 426 426 VAL VAL D . n 
B 2 445 TYR 445 427 427 TYR TYR D . n 
B 2 446 ARG 446 428 428 ARG ARG D . n 
B 2 447 LEU 447 429 429 LEU LEU D . n 
B 2 448 PHE 448 430 430 PHE PHE D . n 
B 2 449 LEU 449 431 431 LEU LEU D . n 
B 2 450 ASP 450 432 432 ASP ASP D . n 
B 2 451 VAL 451 433 433 VAL VAL D . n 
B 2 452 ARG 452 434 434 ARG ARG D . n 
B 2 453 ARG 453 435 435 ARG ARG D . n 
B 2 454 SER 454 436 436 SER SER D . n 
B 2 455 MET 455 437 437 MET MET D . n 
B 2 456 GLN 456 438 438 GLN GLN D . n 
B 2 457 TYR 457 439 439 TYR TYR D . n 
B 2 458 LEU 458 440 440 LEU LEU D . n 
B 2 459 VAL 459 441 441 VAL VAL D . n 
B 2 460 GLU 460 442 442 GLU GLU D . n 
B 2 461 TYR 461 443 443 TYR TYR D . n 
B 2 462 GLN 462 444 444 GLN GLN D . n 
B 2 463 SER 463 445 445 SER SER D . n 
B 2 464 GLN 464 446 446 GLN GLN D . n 
B 2 465 TYR 465 447 447 TYR TYR D . n 
B 2 466 MET 466 448 448 MET MET D . n 
B 2 467 PHE 467 449 ?   ?   ?   D . n 
B 2 468 SER 468 450 ?   ?   ?   D . n 
B 2 469 GLU 469 451 ?   ?   ?   D . n 
B 2 470 PRO 470 452 ?   ?   ?   D . n 
B 2 471 ILE 471 453 ?   ?   ?   D . n 
B 2 472 LYS 472 454 ?   ?   ?   D . n 
B 2 473 ASN 473 455 ?   ?   ?   D . n 
B 2 474 ASP 474 456 ?   ?   ?   D . n 
B 2 475 GLU 475 457 ?   ?   ?   D . n 
B 2 476 ALA 476 458 ?   ?   ?   D . n 
B 2 477 ALA 477 459 ?   ?   ?   D . n 
B 2 478 ALA 478 460 ?   ?   ?   D . n 
B 2 479 GLU 479 461 ?   ?   ?   D . n 
B 2 480 ASP 480 462 ?   ?   ?   D . n 
B 2 481 GLU 481 463 ?   ?   ?   D . n 
B 2 482 GLN 482 464 ?   ?   ?   D . n 
B 2 483 ASP 483 465 ?   ?   ?   D . n 
B 2 484 ALA 484 466 ?   ?   ?   D . n 
B 2 485 MET 485 467 ?   ?   ?   D . n 
B 2 486 GLN 486 468 ?   ?   ?   D . n 
B 2 487 ILE 487 469 ?   ?   ?   D . n 
C 1 1   MET 1   -28 ?   ?   ?   C . n 
C 1 2   GLY 2   -27 ?   ?   ?   C . n 
C 1 3   SER 3   -26 ?   ?   ?   C . n 
C 1 4   SER 4   -25 ?   ?   ?   C . n 
C 1 5   HIS 5   -24 ?   ?   ?   C . n 
C 1 6   HIS 6   -23 ?   ?   ?   C . n 
C 1 7   HIS 7   -22 ?   ?   ?   C . n 
C 1 8   HIS 8   -21 ?   ?   ?   C . n 
C 1 9   HIS 9   -20 ?   ?   ?   C . n 
C 1 10  HIS 10  -19 ?   ?   ?   C . n 
C 1 11  HIS 11  -18 ?   ?   ?   C . n 
C 1 12  HIS 12  -17 ?   ?   ?   C . n 
C 1 13  SER 13  -16 ?   ?   ?   C . n 
C 1 14  SER 14  -15 ?   ?   ?   C . n 
C 1 15  GLY 15  -14 ?   ?   ?   C . n 
C 1 16  GLU 16  -13 ?   ?   ?   C . n 
C 1 17  ASN 17  -12 ?   ?   ?   C . n 
C 1 18  LEU 18  -11 ?   ?   ?   C . n 
C 1 19  TYR 19  -10 ?   ?   ?   C . n 
C 1 20  PHE 20  -9  ?   ?   ?   C . n 
C 1 21  GLN 21  -8  ?   ?   ?   C . n 
C 1 22  GLY 22  -7  ?   ?   ?   C . n 
C 1 23  SER 23  -6  ?   ?   ?   C . n 
C 1 24  HIS 24  -5  ?   ?   ?   C . n 
C 1 25  MET 25  -4  ?   ?   ?   C . n 
C 1 26  LEU 26  -3  ?   ?   ?   C . n 
C 1 27  GLU 27  -2  ?   ?   ?   C . n 
C 1 28  ASP 28  -1  ?   ?   ?   C . n 
C 1 29  PRO 29  0   ?   ?   ?   C . n 
C 1 30  MET 30  1   ?   ?   ?   C . n 
C 1 31  GLU 31  2   ?   ?   ?   C . n 
C 1 32  LYS 32  3   ?   ?   ?   C . n 
C 1 33  VAL 33  4   ?   ?   ?   C . n 
C 1 34  LYS 34  5   ?   ?   ?   C . n 
C 1 35  ILE 35  6   ?   ?   ?   C . n 
C 1 36  GLU 36  7   ?   ?   ?   C . n 
C 1 37  GLU 37  8   ?   ?   ?   C . n 
C 1 38  ILE 38  9   ?   ?   ?   C . n 
C 1 39  GLN 39  10  ?   ?   ?   C . n 
C 1 40  SER 40  11  ?   ?   ?   C . n 
C 1 41  THR 41  12  ?   ?   ?   C . n 
C 1 42  ALA 42  13  ?   ?   ?   C . n 
C 1 43  LYS 43  14  ?   ?   ?   C . n 
C 1 44  LYS 44  15  ?   ?   ?   C . n 
C 1 45  GLN 45  16  ?   ?   ?   C . n 
C 1 46  ARG 46  17  ?   ?   ?   C . n 
C 1 47  ILE 47  18  18  ILE ILE C . n 
C 1 48  ALA 48  19  19  ALA ALA C . n 
C 1 49  THR 49  20  20  THR THR C . n 
C 1 50  HIS 50  21  21  HIS HIS C . n 
C 1 51  THR 51  22  22  THR THR C . n 
C 1 52  HIS 52  23  23  HIS HIS C . n 
C 1 53  ILE 53  24  24  ILE ILE C . n 
C 1 54  LYS 54  25  25  LYS LYS C . n 
C 1 55  GLY 55  26  26  GLY GLY C . n 
C 1 56  LEU 56  27  27  LEU LEU C . n 
C 1 57  GLY 57  28  28  GLY GLY C . n 
C 1 58  LEU 58  29  29  LEU LEU C . n 
C 1 59  GLU 59  30  30  GLU GLU C . n 
C 1 60  PRO 60  31  31  PRO PRO C . n 
C 1 61  THR 61  32  32  THR THR C . n 
C 1 62  GLY 62  33  33  GLY GLY C . n 
C 1 63  ILE 63  34  34  ILE ILE C . n 
C 1 64  PRO 64  35  35  PRO PRO C . n 
C 1 65  ILE 65  36  36  ILE ILE C . n 
C 1 66  LYS 66  37  37  LYS LYS C . n 
C 1 67  LEU 67  38  38  LEU LEU C . n 
C 1 68  ALA 68  39  39  ALA ALA C . n 
C 1 69  ALA 69  40  40  ALA ALA C . n 
C 1 70  GLY 70  41  41  GLY GLY C . n 
C 1 71  PHE 71  42  42  PHE PHE C . n 
C 1 72  VAL 72  43  43  VAL VAL C . n 
C 1 73  GLY 73  44  44  GLY GLY C . n 
C 1 74  GLN 74  45  45  GLN GLN C . n 
C 1 75  LEU 75  46  46  LEU LEU C . n 
C 1 76  GLU 76  47  47  GLU GLU C . n 
C 1 77  ALA 77  48  48  ALA ALA C . n 
C 1 78  ARG 78  49  49  ARG ARG C . n 
C 1 79  GLU 79  50  50  GLU GLU C . n 
C 1 80  ALA 80  51  51  ALA ALA C . n 
C 1 81  ALA 81  52  52  ALA ALA C . n 
C 1 82  GLY 82  53  53  GLY GLY C . n 
C 1 83  LEU 83  54  54  LEU LEU C . n 
C 1 84  VAL 84  55  55  VAL VAL C . n 
C 1 85  VAL 85  56  56  VAL VAL C . n 
C 1 86  ASP 86  57  57  ASP ASP C . n 
C 1 87  MET 87  58  58  MET MET C . n 
C 1 88  ILE 88  59  59  ILE ILE C . n 
C 1 89  LYS 89  60  60  LYS LYS C . n 
C 1 90  GLN 90  61  61  GLN GLN C . n 
C 1 91  LYS 91  62  62  LYS LYS C . n 
C 1 92  LYS 92  63  63  LYS LYS C . n 
C 1 93  MET 93  64  64  MET MET C . n 
C 1 94  ALA 94  65  65  ALA ALA C . n 
C 1 95  GLY 95  66  66  GLY GLY C . n 
C 1 96  LYS 96  67  67  LYS LYS C . n 
C 1 97  ALA 97  68  68  ALA ALA C . n 
C 1 98  LEU 98  69  69  LEU LEU C . n 
C 1 99  LEU 99  70  70  LEU LEU C . n 
C 1 100 LEU 100 71  71  LEU LEU C . n 
C 1 101 ALA 101 72  72  ALA ALA C . n 
C 1 102 GLY 102 73  73  GLY GLY C . n 
C 1 103 PRO 103 74  74  PRO PRO C . n 
C 1 104 PRO 104 75  75  PRO PRO C . n 
C 1 105 GLY 105 76  76  GLY GLY C . n 
C 1 106 THR 106 77  77  THR THR C . n 
C 1 107 GLY 107 78  78  GLY GLY C . n 
C 1 108 LYS 108 79  79  LYS LYS C . n 
C 1 109 THR 109 80  80  THR THR C . n 
C 1 110 ALA 110 81  81  ALA ALA C . n 
C 1 111 LEU 111 82  82  LEU LEU C . n 
C 1 112 ALA 112 83  83  ALA ALA C . n 
C 1 113 LEU 113 84  84  LEU LEU C . n 
C 1 114 GLY 114 85  85  GLY GLY C . n 
C 1 115 ILE 115 86  86  ILE ILE C . n 
C 1 116 SER 116 87  87  SER SER C . n 
C 1 117 GLN 117 88  88  GLN GLN C . n 
C 1 118 GLU 118 89  89  GLU GLU C . n 
C 1 119 LEU 119 90  90  LEU LEU C . n 
C 1 120 GLY 120 91  91  GLY GLY C . n 
C 1 121 SER 121 92  92  SER SER C . n 
C 1 122 LYS 122 93  93  LYS LYS C . n 
C 1 123 VAL 123 94  94  VAL VAL C . n 
C 1 124 PRO 124 95  95  PRO PRO C . n 
C 1 125 PHE 125 96  96  PHE PHE C . n 
C 1 126 CYS 126 97  97  CYS CYS C . n 
C 1 127 PRO 127 98  98  PRO PRO C . n 
C 1 128 MET 128 99  99  MET MET C . n 
C 1 129 VAL 129 100 100 VAL VAL C . n 
C 1 130 GLY 130 101 101 GLY GLY C . n 
C 1 131 SER 131 102 102 SER SER C . n 
C 1 132 GLU 132 103 103 GLU GLU C . n 
C 1 133 VAL 133 104 104 VAL VAL C . n 
C 1 134 TYR 134 105 105 TYR TYR C . n 
C 1 135 SER 135 106 106 SER SER C . n 
C 1 136 SER 136 107 107 SER SER C . n 
C 1 137 GLU 137 108 108 GLU GLU C . n 
C 1 138 VAL 138 109 109 VAL VAL C . n 
C 1 139 LYS 139 110 110 LYS LYS C . n 
C 1 140 LYS 140 111 111 LYS LYS C . n 
C 1 141 THR 141 112 112 THR THR C . n 
C 1 142 GLU 142 113 113 GLU GLU C . n 
C 1 143 VAL 143 114 114 VAL VAL C . n 
C 1 144 LEU 144 115 115 LEU LEU C . n 
C 1 145 MET 145 116 116 MET MET C . n 
C 1 146 GLU 146 117 117 GLU GLU C . n 
C 1 147 ASN 147 118 118 ASN ASN C . n 
C 1 148 PHE 148 119 119 PHE PHE C . n 
C 1 149 ARG 149 120 120 ARG ARG C . n 
C 1 150 ARG 150 121 121 ARG ARG C . n 
C 1 151 ALA 151 122 122 ALA ALA C . n 
C 1 152 ILE 152 123 123 ILE ILE C . n 
C 1 153 GLY 153 124 124 GLY GLY C . n 
C 1 154 LEU 154 125 125 LEU LEU C . n 
C 1 155 ARG 155 126 126 ARG ARG C . n 
C 1 156 ILE 156 127 127 ILE ILE C . n 
C 1 157 LYS 157 128 128 LYS LYS C . n 
C 1 158 GLU 158 129 ?   ?   ?   C . n 
C 1 159 THR 159 130 ?   ?   ?   C . n 
C 1 160 LYS 160 131 ?   ?   ?   C . n 
C 1 161 GLU 161 132 ?   ?   ?   C . n 
C 1 162 VAL 162 133 ?   ?   ?   C . n 
C 1 163 TYR 163 134 ?   ?   ?   C . n 
C 1 164 GLU 164 135 ?   ?   ?   C . n 
C 1 165 GLY 165 136 ?   ?   ?   C . n 
C 1 166 GLU 166 137 ?   ?   ?   C . n 
C 1 167 VAL 167 138 ?   ?   ?   C . n 
C 1 168 THR 168 139 ?   ?   ?   C . n 
C 1 169 GLU 169 140 ?   ?   ?   C . n 
C 1 170 LEU 170 141 ?   ?   ?   C . n 
C 1 171 SER 171 142 ?   ?   ?   C . n 
C 1 172 PRO 172 143 ?   ?   ?   C . n 
C 1 173 GLU 173 144 ?   ?   ?   C . n 
C 1 174 GLU 174 145 ?   ?   ?   C . n 
C 1 175 THR 175 146 ?   ?   ?   C . n 
C 1 176 GLU 176 147 ?   ?   ?   C . n 
C 1 177 SER 177 148 ?   ?   ?   C . n 
C 1 178 LEU 178 149 ?   ?   ?   C . n 
C 1 179 THR 179 150 ?   ?   ?   C . n 
C 1 180 GLY 180 151 ?   ?   ?   C . n 
C 1 181 GLY 181 152 ?   ?   ?   C . n 
C 1 182 TYR 182 153 ?   ?   ?   C . n 
C 1 183 GLY 183 154 ?   ?   ?   C . n 
C 1 184 LYS 184 155 ?   ?   ?   C . n 
C 1 185 SER 185 156 ?   ?   ?   C . n 
C 1 186 ILE 186 157 ?   ?   ?   C . n 
C 1 187 SER 187 158 ?   ?   ?   C . n 
C 1 188 HIS 188 159 ?   ?   ?   C . n 
C 1 189 VAL 189 160 ?   ?   ?   C . n 
C 1 190 VAL 190 161 ?   ?   ?   C . n 
C 1 191 ILE 191 162 ?   ?   ?   C . n 
C 1 192 THR 192 163 ?   ?   ?   C . n 
C 1 193 LEU 193 164 ?   ?   ?   C . n 
C 1 194 LYS 194 165 ?   ?   ?   C . n 
C 1 195 THR 195 166 ?   ?   ?   C . n 
C 1 196 VAL 196 167 ?   ?   ?   C . n 
C 1 197 LYS 197 168 ?   ?   ?   C . n 
C 1 198 GLY 198 169 ?   ?   ?   C . n 
C 1 199 THR 199 170 ?   ?   ?   C . n 
C 1 200 LYS 200 171 ?   ?   ?   C . n 
C 1 201 HIS 201 172 ?   ?   ?   C . n 
C 1 202 LEU 202 173 ?   ?   ?   C . n 
C 1 203 LYS 203 174 ?   ?   ?   C . n 
C 1 204 LEU 204 175 ?   ?   ?   C . n 
C 1 205 ASP 205 176 ?   ?   ?   C . n 
C 1 206 PRO 206 177 ?   ?   ?   C . n 
C 1 207 THR 207 178 ?   ?   ?   C . n 
C 1 208 ILE 208 179 ?   ?   ?   C . n 
C 1 209 TYR 209 180 ?   ?   ?   C . n 
C 1 210 ASP 210 181 ?   ?   ?   C . n 
C 1 211 ALA 211 182 ?   ?   ?   C . n 
C 1 212 LEU 212 183 ?   ?   ?   C . n 
C 1 213 ILE 213 184 ?   ?   ?   C . n 
C 1 214 LYS 214 185 ?   ?   ?   C . n 
C 1 215 GLU 215 186 ?   ?   ?   C . n 
C 1 216 LYS 216 187 ?   ?   ?   C . n 
C 1 217 VAL 217 188 ?   ?   ?   C . n 
C 1 218 ALA 218 189 ?   ?   ?   C . n 
C 1 219 VAL 219 190 ?   ?   ?   C . n 
C 1 220 GLY 220 191 ?   ?   ?   C . n 
C 1 221 ASP 221 192 ?   ?   ?   C . n 
C 1 222 VAL 222 193 ?   ?   ?   C . n 
C 1 223 ILE 223 194 ?   ?   ?   C . n 
C 1 224 TYR 224 195 ?   ?   ?   C . n 
C 1 225 ILE 225 196 ?   ?   ?   C . n 
C 1 226 GLU 226 197 ?   ?   ?   C . n 
C 1 227 ALA 227 198 ?   ?   ?   C . n 
C 1 228 ASN 228 199 ?   ?   ?   C . n 
C 1 229 SER 229 200 ?   ?   ?   C . n 
C 1 230 GLY 230 201 ?   ?   ?   C . n 
C 1 231 ALA 231 202 ?   ?   ?   C . n 
C 1 232 VAL 232 203 ?   ?   ?   C . n 
C 1 233 LYS 233 204 ?   ?   ?   C . n 
C 1 234 ARG 234 205 ?   ?   ?   C . n 
C 1 235 VAL 235 206 ?   ?   ?   C . n 
C 1 236 GLY 236 207 ?   ?   ?   C . n 
C 1 237 ARG 237 208 ?   ?   ?   C . n 
C 1 238 SER 238 209 ?   ?   ?   C . n 
C 1 239 ASP 239 210 ?   ?   ?   C . n 
C 1 240 ALA 240 211 ?   ?   ?   C . n 
C 1 241 PHE 241 212 ?   ?   ?   C . n 
C 1 242 ALA 242 213 ?   ?   ?   C . n 
C 1 243 THR 243 214 ?   ?   ?   C . n 
C 1 244 GLU 244 215 ?   ?   ?   C . n 
C 1 245 PHE 245 216 ?   ?   ?   C . n 
C 1 246 ASP 246 217 ?   ?   ?   C . n 
C 1 247 LEU 247 218 ?   ?   ?   C . n 
C 1 248 GLU 248 219 ?   ?   ?   C . n 
C 1 249 ALA 249 220 ?   ?   ?   C . n 
C 1 250 GLU 250 221 ?   ?   ?   C . n 
C 1 251 GLU 251 222 ?   ?   ?   C . n 
C 1 252 TYR 252 223 ?   ?   ?   C . n 
C 1 253 VAL 253 224 ?   ?   ?   C . n 
C 1 254 PRO 254 225 ?   ?   ?   C . n 
C 1 255 LEU 255 226 ?   ?   ?   C . n 
C 1 256 PRO 256 227 ?   ?   ?   C . n 
C 1 257 LYS 257 228 ?   ?   ?   C . n 
C 1 258 GLY 258 229 ?   ?   ?   C . n 
C 1 259 GLU 259 230 ?   ?   ?   C . n 
C 1 260 VAL 260 231 ?   ?   ?   C . n 
C 1 261 HIS 261 232 ?   ?   ?   C . n 
C 1 262 LYS 262 233 ?   ?   ?   C . n 
C 1 263 LYS 263 234 ?   ?   ?   C . n 
C 1 264 LYS 264 235 ?   ?   ?   C . n 
C 1 265 GLU 265 236 ?   ?   ?   C . n 
C 1 266 ILE 266 237 ?   ?   ?   C . n 
C 1 267 VAL 267 238 238 VAL VAL C . n 
C 1 268 GLN 268 239 239 GLN GLN C . n 
C 1 269 ASP 269 240 240 ASP ASP C . n 
C 1 270 VAL 270 241 241 VAL VAL C . n 
C 1 271 THR 271 242 242 THR THR C . n 
C 1 272 LEU 272 243 243 LEU LEU C . n 
C 1 273 GLN 273 244 244 GLN GLN C . n 
C 1 274 ASP 274 245 245 ASP ASP C . n 
C 1 275 LEU 275 246 246 LEU LEU C . n 
C 1 276 ASP 276 247 247 ASP ASP C . n 
C 1 277 ALA 277 248 248 ALA ALA C . n 
C 1 278 ALA 278 249 249 ALA ALA C . n 
C 1 279 ASN 279 250 250 ASN ASN C . n 
C 1 280 ALA 280 251 251 ALA ALA C . n 
C 1 281 ARG 281 252 ?   ?   ?   C . n 
C 1 282 PRO 282 253 ?   ?   ?   C . n 
C 1 283 GLN 283 254 ?   ?   ?   C . n 
C 1 284 GLY 284 255 ?   ?   ?   C . n 
C 1 285 GLY 285 256 ?   ?   ?   C . n 
C 1 286 GLN 286 257 ?   ?   ?   C . n 
C 1 287 ASP 287 258 ?   ?   ?   C . n 
C 1 288 ILE 288 259 ?   ?   ?   C . n 
C 1 289 LEU 289 260 ?   ?   ?   C . n 
C 1 290 SER 290 261 ?   ?   ?   C . n 
C 1 291 LEU 291 262 ?   ?   ?   C . n 
C 1 292 MET 292 263 ?   ?   ?   C . n 
C 1 293 GLY 293 264 ?   ?   ?   C . n 
C 1 294 GLN 294 265 ?   ?   ?   C . n 
C 1 295 MET 295 266 ?   ?   ?   C . n 
C 1 296 MET 296 267 ?   ?   ?   C . n 
C 1 297 LYS 297 268 ?   ?   ?   C . n 
C 1 298 PRO 298 269 ?   ?   ?   C . n 
C 1 299 ARG 299 270 ?   ?   ?   C . n 
C 1 300 LYS 300 271 ?   ?   ?   C . n 
C 1 301 THR 301 272 ?   ?   ?   C . n 
C 1 302 GLU 302 273 ?   ?   ?   C . n 
C 1 303 ILE 303 274 ?   ?   ?   C . n 
C 1 304 THR 304 275 ?   ?   ?   C . n 
C 1 305 ASP 305 276 ?   ?   ?   C . n 
C 1 306 LYS 306 277 277 LYS LYS C . n 
C 1 307 LEU 307 278 278 LEU LEU C . n 
C 1 308 ARG 308 279 279 ARG ARG C . n 
C 1 309 GLN 309 280 280 GLN GLN C . n 
C 1 310 GLU 310 281 281 GLU GLU C . n 
C 1 311 ILE 311 282 282 ILE ILE C . n 
C 1 312 ASN 312 283 283 ASN ASN C . n 
C 1 313 LYS 313 284 284 LYS LYS C . n 
C 1 314 VAL 314 285 285 VAL VAL C . n 
C 1 315 VAL 315 286 286 VAL VAL C . n 
C 1 316 ASN 316 287 287 ASN ASN C . n 
C 1 317 ARG 317 288 288 ARG ARG C . n 
C 1 318 TYR 318 289 289 TYR TYR C . n 
C 1 319 ILE 319 290 290 ILE ILE C . n 
C 1 320 ASP 320 291 291 ASP ASP C . n 
C 1 321 GLU 321 292 292 GLU GLU C . n 
C 1 322 GLY 322 293 293 GLY GLY C . n 
C 1 323 VAL 323 294 294 VAL VAL C . n 
C 1 324 ALA 324 295 295 ALA ALA C . n 
C 1 325 GLU 325 296 296 GLU GLU C . n 
C 1 326 LEU 326 297 297 LEU LEU C . n 
C 1 327 VAL 327 298 298 VAL VAL C . n 
C 1 328 PRO 328 299 299 PRO PRO C . n 
C 1 329 GLY 329 300 300 GLY GLY C . n 
C 1 330 VAL 330 301 301 VAL VAL C . n 
C 1 331 LEU 331 302 302 LEU LEU C . n 
C 1 332 PHE 332 303 303 PHE PHE C . n 
C 1 333 ILE 333 304 304 ILE ILE C . n 
C 1 334 ASP 334 305 305 ASP ASP C . n 
C 1 335 GLU 335 306 306 GLU GLU C . n 
C 1 336 VAL 336 307 307 VAL VAL C . n 
C 1 337 HIS 337 308 308 HIS HIS C . n 
C 1 338 MET 338 309 309 MET MET C . n 
C 1 339 LEU 339 310 310 LEU LEU C . n 
C 1 340 ASP 340 311 311 ASP ASP C . n 
C 1 341 MET 341 312 312 MET MET C . n 
C 1 342 GLU 342 313 313 GLU GLU C . n 
C 1 343 CYS 343 314 314 CYS CYS C . n 
C 1 344 PHE 344 315 315 PHE PHE C . n 
C 1 345 SER 345 316 316 SER SER C . n 
C 1 346 TYR 346 317 317 TYR TYR C . n 
C 1 347 LEU 347 318 318 LEU LEU C . n 
C 1 348 ASN 348 319 319 ASN ASN C . n 
C 1 349 ARG 349 320 320 ARG ARG C . n 
C 1 350 ALA 350 321 321 ALA ALA C . n 
C 1 351 LEU 351 322 322 LEU LEU C . n 
C 1 352 GLU 352 323 323 GLU GLU C . n 
C 1 353 SER 353 324 324 SER SER C . n 
C 1 354 SER 354 325 325 SER SER C . n 
C 1 355 LEU 355 326 326 LEU LEU C . n 
C 1 356 SER 356 327 327 SER SER C . n 
C 1 357 PRO 357 328 328 PRO PRO C . n 
C 1 358 ILE 358 329 329 ILE ILE C . n 
C 1 359 VAL 359 330 330 VAL VAL C . n 
C 1 360 ILE 360 331 331 ILE ILE C . n 
C 1 361 PHE 361 332 332 PHE PHE C . n 
C 1 362 ALA 362 333 333 ALA ALA C . n 
C 1 363 THR 363 334 334 THR THR C . n 
C 1 364 ASN 364 335 335 ASN ASN C . n 
C 1 365 ARG 365 336 336 ARG ARG C . n 
C 1 366 GLY 366 337 337 GLY GLY C . n 
C 1 367 VAL 367 338 338 VAL VAL C . n 
C 1 368 CYS 368 339 339 CYS CYS C . n 
C 1 369 ASN 369 340 340 ASN ASN C . n 
C 1 370 VAL 370 341 341 VAL VAL C . n 
C 1 371 ARG 371 342 342 ARG ARG C . n 
C 1 372 GLY 372 343 343 GLY GLY C . n 
C 1 373 THR 373 344 344 THR THR C . n 
C 1 374 ASP 374 345 345 ASP ASP C . n 
C 1 375 MET 375 346 346 MET MET C . n 
C 1 376 PRO 376 347 347 PRO PRO C . n 
C 1 377 SER 377 348 348 SER SER C . n 
C 1 378 PRO 378 349 349 PRO PRO C . n 
C 1 379 HIS 379 350 350 HIS HIS C . n 
C 1 380 GLY 380 351 351 GLY GLY C . n 
C 1 381 VAL 381 352 352 VAL VAL C . n 
C 1 382 PRO 382 353 353 PRO PRO C . n 
C 1 383 ILE 383 354 354 ILE ILE C . n 
C 1 384 ASP 384 355 355 ASP ASP C . n 
C 1 385 LEU 385 356 356 LEU LEU C . n 
C 1 386 LEU 386 357 357 LEU LEU C . n 
C 1 387 ASP 387 358 358 ASP ASP C . n 
C 1 388 ARG 388 359 359 ARG ARG C . n 
C 1 389 LEU 389 360 360 LEU LEU C . n 
C 1 390 VAL 390 361 361 VAL VAL C . n 
C 1 391 ILE 391 362 362 ILE ILE C . n 
C 1 392 ILE 392 363 363 ILE ILE C . n 
C 1 393 ARG 393 364 364 ARG ARG C . n 
C 1 394 THR 394 365 365 THR THR C . n 
C 1 395 GLN 395 366 366 GLN GLN C . n 
C 1 396 ILE 396 367 367 ILE ILE C . n 
C 1 397 TYR 397 368 368 TYR TYR C . n 
C 1 398 ASP 398 369 369 ASP ASP C . n 
C 1 399 PRO 399 370 370 PRO PRO C . n 
C 1 400 SER 400 371 371 SER SER C . n 
C 1 401 GLU 401 372 372 GLU GLU C . n 
C 1 402 MET 402 373 373 MET MET C . n 
C 1 403 ILE 403 374 374 ILE ILE C . n 
C 1 404 GLN 404 375 375 GLN GLN C . n 
C 1 405 ILE 405 376 376 ILE ILE C . n 
C 1 406 ILE 406 377 377 ILE ILE C . n 
C 1 407 ALA 407 378 378 ALA ALA C . n 
C 1 408 ILE 408 379 379 ILE ILE C . n 
C 1 409 ARG 409 380 380 ARG ARG C . n 
C 1 410 ALA 410 381 381 ALA ALA C . n 
C 1 411 GLN 411 382 382 GLN GLN C . n 
C 1 412 VAL 412 383 383 VAL VAL C . n 
C 1 413 GLU 413 384 384 GLU GLU C . n 
C 1 414 GLU 414 385 385 GLU GLU C . n 
C 1 415 LEU 415 386 386 LEU LEU C . n 
C 1 416 THR 416 387 387 THR THR C . n 
C 1 417 VAL 417 388 388 VAL VAL C . n 
C 1 418 ASP 418 389 389 ASP ASP C . n 
C 1 419 GLU 419 390 390 GLU GLU C . n 
C 1 420 GLU 420 391 391 GLU GLU C . n 
C 1 421 CYS 421 392 392 CYS CYS C . n 
C 1 422 LEU 422 393 393 LEU LEU C . n 
C 1 423 VAL 423 394 394 VAL VAL C . n 
C 1 424 LEU 424 395 395 LEU LEU C . n 
C 1 425 LEU 425 396 396 LEU LEU C . n 
C 1 426 GLY 426 397 397 GLY GLY C . n 
C 1 427 GLU 427 398 398 GLU GLU C . n 
C 1 428 ILE 428 399 399 ILE ILE C . n 
C 1 429 GLY 429 400 400 GLY GLY C . n 
C 1 430 GLN 430 401 401 GLN GLN C . n 
C 1 431 ARG 431 402 402 ARG ARG C . n 
C 1 432 THR 432 403 403 THR THR C . n 
C 1 433 SER 433 404 404 SER SER C . n 
C 1 434 LEU 434 405 405 LEU LEU C . n 
C 1 435 ARG 435 406 406 ARG ARG C . n 
C 1 436 HIS 436 407 407 HIS HIS C . n 
C 1 437 ALA 437 408 408 ALA ALA C . n 
C 1 438 VAL 438 409 409 VAL VAL C . n 
C 1 439 GLN 439 410 410 GLN GLN C . n 
C 1 440 LEU 440 411 411 LEU LEU C . n 
C 1 441 LEU 441 412 412 LEU LEU C . n 
C 1 442 SER 442 413 413 SER SER C . n 
C 1 443 PRO 443 414 414 PRO PRO C . n 
C 1 444 ALA 444 415 415 ALA ALA C . n 
C 1 445 SER 445 416 416 SER SER C . n 
C 1 446 ILE 446 417 417 ILE ILE C . n 
C 1 447 VAL 447 418 418 VAL VAL C . n 
C 1 448 ALA 448 419 419 ALA ALA C . n 
C 1 449 LYS 449 420 420 LYS LYS C . n 
C 1 450 MET 450 421 421 MET MET C . n 
C 1 451 ASN 451 422 422 ASN ASN C . n 
C 1 452 GLY 452 423 423 GLY GLY C . n 
C 1 453 ARG 453 424 424 ARG ARG C . n 
C 1 454 ASP 454 425 425 ASP ASP C . n 
C 1 455 ASN 455 426 426 ASN ASN C . n 
C 1 456 ILE 456 427 427 ILE ILE C . n 
C 1 457 CYS 457 428 428 CYS CYS C . n 
C 1 458 LYS 458 429 429 LYS LYS C . n 
C 1 459 ALA 459 430 430 ALA ALA C . n 
C 1 460 ASP 460 431 431 ASP ASP C . n 
C 1 461 ILE 461 432 432 ILE ILE C . n 
C 1 462 GLU 462 433 433 GLU GLU C . n 
C 1 463 GLU 463 434 434 GLU GLU C . n 
C 1 464 VAL 464 435 435 VAL VAL C . n 
C 1 465 THR 465 436 436 THR THR C . n 
C 1 466 SER 466 437 437 SER SER C . n 
C 1 467 LEU 467 438 438 LEU LEU C . n 
C 1 468 TYR 468 439 439 TYR TYR C . n 
C 1 469 LEU 469 440 440 LEU LEU C . n 
C 1 470 ASP 470 441 441 ASP ASP C . n 
C 1 471 ALA 471 442 442 ALA ALA C . n 
C 1 472 LYS 472 443 443 LYS LYS C . n 
C 1 473 SER 473 444 444 SER SER C . n 
C 1 474 SER 474 445 445 SER SER C . n 
C 1 475 ALA 475 446 446 ALA ALA C . n 
C 1 476 LYS 476 447 447 LYS LYS C . n 
C 1 477 LEU 477 448 448 LEU LEU C . n 
C 1 478 LEU 478 449 449 LEU LEU C . n 
C 1 479 HIS 479 450 450 HIS HIS C . n 
C 1 480 GLU 480 451 451 GLU GLU C . n 
C 1 481 GLN 481 452 452 GLN GLN C . n 
C 1 482 GLN 482 453 ?   ?   ?   C . n 
C 1 483 GLU 483 454 ?   ?   ?   C . n 
C 1 484 LYS 484 455 ?   ?   ?   C . n 
C 1 485 TYR 485 456 ?   ?   ?   C . n 
C 1 486 ILE 486 457 ?   ?   ?   C . n 
C 1 487 SER 487 458 ?   ?   ?   C . n 
D 1 1   MET 1   -28 ?   ?   ?   B . n 
D 1 2   GLY 2   -27 ?   ?   ?   B . n 
D 1 3   SER 3   -26 ?   ?   ?   B . n 
D 1 4   SER 4   -25 ?   ?   ?   B . n 
D 1 5   HIS 5   -24 ?   ?   ?   B . n 
D 1 6   HIS 6   -23 ?   ?   ?   B . n 
D 1 7   HIS 7   -22 ?   ?   ?   B . n 
D 1 8   HIS 8   -21 ?   ?   ?   B . n 
D 1 9   HIS 9   -20 ?   ?   ?   B . n 
D 1 10  HIS 10  -19 ?   ?   ?   B . n 
D 1 11  HIS 11  -18 ?   ?   ?   B . n 
D 1 12  HIS 12  -17 ?   ?   ?   B . n 
D 1 13  SER 13  -16 ?   ?   ?   B . n 
D 1 14  SER 14  -15 ?   ?   ?   B . n 
D 1 15  GLY 15  -14 ?   ?   ?   B . n 
D 1 16  GLU 16  -13 ?   ?   ?   B . n 
D 1 17  ASN 17  -12 ?   ?   ?   B . n 
D 1 18  LEU 18  -11 ?   ?   ?   B . n 
D 1 19  TYR 19  -10 ?   ?   ?   B . n 
D 1 20  PHE 20  -9  ?   ?   ?   B . n 
D 1 21  GLN 21  -8  ?   ?   ?   B . n 
D 1 22  GLY 22  -7  ?   ?   ?   B . n 
D 1 23  SER 23  -6  ?   ?   ?   B . n 
D 1 24  HIS 24  -5  ?   ?   ?   B . n 
D 1 25  MET 25  -4  ?   ?   ?   B . n 
D 1 26  LEU 26  -3  ?   ?   ?   B . n 
D 1 27  GLU 27  -2  ?   ?   ?   B . n 
D 1 28  ASP 28  -1  ?   ?   ?   B . n 
D 1 29  PRO 29  0   ?   ?   ?   B . n 
D 1 30  MET 30  1   ?   ?   ?   B . n 
D 1 31  GLU 31  2   ?   ?   ?   B . n 
D 1 32  LYS 32  3   ?   ?   ?   B . n 
D 1 33  VAL 33  4   ?   ?   ?   B . n 
D 1 34  LYS 34  5   ?   ?   ?   B . n 
D 1 35  ILE 35  6   ?   ?   ?   B . n 
D 1 36  GLU 36  7   ?   ?   ?   B . n 
D 1 37  GLU 37  8   ?   ?   ?   B . n 
D 1 38  ILE 38  9   ?   ?   ?   B . n 
D 1 39  GLN 39  10  ?   ?   ?   B . n 
D 1 40  SER 40  11  ?   ?   ?   B . n 
D 1 41  THR 41  12  ?   ?   ?   B . n 
D 1 42  ALA 42  13  ?   ?   ?   B . n 
D 1 43  LYS 43  14  ?   ?   ?   B . n 
D 1 44  LYS 44  15  ?   ?   ?   B . n 
D 1 45  GLN 45  16  ?   ?   ?   B . n 
D 1 46  ARG 46  17  ?   ?   ?   B . n 
D 1 47  ILE 47  18  18  ILE ILE B . n 
D 1 48  ALA 48  19  19  ALA ALA B . n 
D 1 49  THR 49  20  20  THR THR B . n 
D 1 50  HIS 50  21  21  HIS HIS B . n 
D 1 51  THR 51  22  22  THR THR B . n 
D 1 52  HIS 52  23  23  HIS HIS B . n 
D 1 53  ILE 53  24  24  ILE ILE B . n 
D 1 54  LYS 54  25  25  LYS LYS B . n 
D 1 55  GLY 55  26  26  GLY GLY B . n 
D 1 56  LEU 56  27  27  LEU LEU B . n 
D 1 57  GLY 57  28  28  GLY GLY B . n 
D 1 58  LEU 58  29  29  LEU LEU B . n 
D 1 59  GLU 59  30  30  GLU GLU B . n 
D 1 60  PRO 60  31  31  PRO PRO B . n 
D 1 61  THR 61  32  32  THR THR B . n 
D 1 62  GLY 62  33  33  GLY GLY B . n 
D 1 63  ILE 63  34  34  ILE ILE B . n 
D 1 64  PRO 64  35  35  PRO PRO B . n 
D 1 65  ILE 65  36  36  ILE ILE B . n 
D 1 66  LYS 66  37  37  LYS LYS B . n 
D 1 67  LEU 67  38  38  LEU LEU B . n 
D 1 68  ALA 68  39  39  ALA ALA B . n 
D 1 69  ALA 69  40  40  ALA ALA B . n 
D 1 70  GLY 70  41  41  GLY GLY B . n 
D 1 71  PHE 71  42  42  PHE PHE B . n 
D 1 72  VAL 72  43  43  VAL VAL B . n 
D 1 73  GLY 73  44  44  GLY GLY B . n 
D 1 74  GLN 74  45  45  GLN GLN B . n 
D 1 75  LEU 75  46  46  LEU LEU B . n 
D 1 76  GLU 76  47  47  GLU GLU B . n 
D 1 77  ALA 77  48  48  ALA ALA B . n 
D 1 78  ARG 78  49  49  ARG ARG B . n 
D 1 79  GLU 79  50  50  GLU GLU B . n 
D 1 80  ALA 80  51  51  ALA ALA B . n 
D 1 81  ALA 81  52  52  ALA ALA B . n 
D 1 82  GLY 82  53  53  GLY GLY B . n 
D 1 83  LEU 83  54  54  LEU LEU B . n 
D 1 84  VAL 84  55  55  VAL VAL B . n 
D 1 85  VAL 85  56  56  VAL VAL B . n 
D 1 86  ASP 86  57  57  ASP ASP B . n 
D 1 87  MET 87  58  58  MET MET B . n 
D 1 88  ILE 88  59  59  ILE ILE B . n 
D 1 89  LYS 89  60  60  LYS LYS B . n 
D 1 90  GLN 90  61  61  GLN GLN B . n 
D 1 91  LYS 91  62  62  LYS LYS B . n 
D 1 92  LYS 92  63  63  LYS LYS B . n 
D 1 93  MET 93  64  64  MET MET B . n 
D 1 94  ALA 94  65  65  ALA ALA B . n 
D 1 95  GLY 95  66  66  GLY GLY B . n 
D 1 96  LYS 96  67  67  LYS LYS B . n 
D 1 97  ALA 97  68  68  ALA ALA B . n 
D 1 98  LEU 98  69  69  LEU LEU B . n 
D 1 99  LEU 99  70  70  LEU LEU B . n 
D 1 100 LEU 100 71  71  LEU LEU B . n 
D 1 101 ALA 101 72  72  ALA ALA B . n 
D 1 102 GLY 102 73  73  GLY GLY B . n 
D 1 103 PRO 103 74  74  PRO PRO B . n 
D 1 104 PRO 104 75  75  PRO PRO B . n 
D 1 105 GLY 105 76  76  GLY GLY B . n 
D 1 106 THR 106 77  77  THR THR B . n 
D 1 107 GLY 107 78  78  GLY GLY B . n 
D 1 108 LYS 108 79  79  LYS LYS B . n 
D 1 109 THR 109 80  80  THR THR B . n 
D 1 110 ALA 110 81  81  ALA ALA B . n 
D 1 111 LEU 111 82  82  LEU LEU B . n 
D 1 112 ALA 112 83  83  ALA ALA B . n 
D 1 113 LEU 113 84  84  LEU LEU B . n 
D 1 114 GLY 114 85  85  GLY GLY B . n 
D 1 115 ILE 115 86  86  ILE ILE B . n 
D 1 116 SER 116 87  87  SER SER B . n 
D 1 117 GLN 117 88  88  GLN GLN B . n 
D 1 118 GLU 118 89  89  GLU GLU B . n 
D 1 119 LEU 119 90  90  LEU LEU B . n 
D 1 120 GLY 120 91  91  GLY GLY B . n 
D 1 121 SER 121 92  92  SER SER B . n 
D 1 122 LYS 122 93  93  LYS LYS B . n 
D 1 123 VAL 123 94  94  VAL VAL B . n 
D 1 124 PRO 124 95  95  PRO PRO B . n 
D 1 125 PHE 125 96  96  PHE PHE B . n 
D 1 126 CYS 126 97  97  CYS CYS B . n 
D 1 127 PRO 127 98  98  PRO PRO B . n 
D 1 128 MET 128 99  99  MET MET B . n 
D 1 129 VAL 129 100 100 VAL VAL B . n 
D 1 130 GLY 130 101 101 GLY GLY B . n 
D 1 131 SER 131 102 102 SER SER B . n 
D 1 132 GLU 132 103 103 GLU GLU B . n 
D 1 133 VAL 133 104 104 VAL VAL B . n 
D 1 134 TYR 134 105 105 TYR TYR B . n 
D 1 135 SER 135 106 106 SER SER B . n 
D 1 136 SER 136 107 107 SER SER B . n 
D 1 137 GLU 137 108 108 GLU GLU B . n 
D 1 138 VAL 138 109 109 VAL VAL B . n 
D 1 139 LYS 139 110 110 LYS LYS B . n 
D 1 140 LYS 140 111 111 LYS LYS B . n 
D 1 141 THR 141 112 112 THR THR B . n 
D 1 142 GLU 142 113 113 GLU GLU B . n 
D 1 143 VAL 143 114 114 VAL VAL B . n 
D 1 144 LEU 144 115 115 LEU LEU B . n 
D 1 145 MET 145 116 116 MET MET B . n 
D 1 146 GLU 146 117 117 GLU GLU B . n 
D 1 147 ASN 147 118 118 ASN ASN B . n 
D 1 148 PHE 148 119 119 PHE PHE B . n 
D 1 149 ARG 149 120 120 ARG ARG B . n 
D 1 150 ARG 150 121 121 ARG ARG B . n 
D 1 151 ALA 151 122 122 ALA ALA B . n 
D 1 152 ILE 152 123 123 ILE ILE B . n 
D 1 153 GLY 153 124 124 GLY GLY B . n 
D 1 154 LEU 154 125 125 LEU LEU B . n 
D 1 155 ARG 155 126 126 ARG ARG B . n 
D 1 156 ILE 156 127 127 ILE ILE B . n 
D 1 157 LYS 157 128 128 LYS LYS B . n 
D 1 158 GLU 158 129 ?   ?   ?   B . n 
D 1 159 THR 159 130 ?   ?   ?   B . n 
D 1 160 LYS 160 131 ?   ?   ?   B . n 
D 1 161 GLU 161 132 ?   ?   ?   B . n 
D 1 162 VAL 162 133 ?   ?   ?   B . n 
D 1 163 TYR 163 134 ?   ?   ?   B . n 
D 1 164 GLU 164 135 ?   ?   ?   B . n 
D 1 165 GLY 165 136 ?   ?   ?   B . n 
D 1 166 GLU 166 137 ?   ?   ?   B . n 
D 1 167 VAL 167 138 ?   ?   ?   B . n 
D 1 168 THR 168 139 ?   ?   ?   B . n 
D 1 169 GLU 169 140 ?   ?   ?   B . n 
D 1 170 LEU 170 141 ?   ?   ?   B . n 
D 1 171 SER 171 142 ?   ?   ?   B . n 
D 1 172 PRO 172 143 ?   ?   ?   B . n 
D 1 173 GLU 173 144 ?   ?   ?   B . n 
D 1 174 GLU 174 145 ?   ?   ?   B . n 
D 1 175 THR 175 146 ?   ?   ?   B . n 
D 1 176 GLU 176 147 ?   ?   ?   B . n 
D 1 177 SER 177 148 ?   ?   ?   B . n 
D 1 178 LEU 178 149 ?   ?   ?   B . n 
D 1 179 THR 179 150 ?   ?   ?   B . n 
D 1 180 GLY 180 151 ?   ?   ?   B . n 
D 1 181 GLY 181 152 ?   ?   ?   B . n 
D 1 182 TYR 182 153 ?   ?   ?   B . n 
D 1 183 GLY 183 154 ?   ?   ?   B . n 
D 1 184 LYS 184 155 ?   ?   ?   B . n 
D 1 185 SER 185 156 ?   ?   ?   B . n 
D 1 186 ILE 186 157 ?   ?   ?   B . n 
D 1 187 SER 187 158 ?   ?   ?   B . n 
D 1 188 HIS 188 159 ?   ?   ?   B . n 
D 1 189 VAL 189 160 ?   ?   ?   B . n 
D 1 190 VAL 190 161 ?   ?   ?   B . n 
D 1 191 ILE 191 162 ?   ?   ?   B . n 
D 1 192 THR 192 163 ?   ?   ?   B . n 
D 1 193 LEU 193 164 ?   ?   ?   B . n 
D 1 194 LYS 194 165 ?   ?   ?   B . n 
D 1 195 THR 195 166 ?   ?   ?   B . n 
D 1 196 VAL 196 167 ?   ?   ?   B . n 
D 1 197 LYS 197 168 ?   ?   ?   B . n 
D 1 198 GLY 198 169 ?   ?   ?   B . n 
D 1 199 THR 199 170 ?   ?   ?   B . n 
D 1 200 LYS 200 171 ?   ?   ?   B . n 
D 1 201 HIS 201 172 ?   ?   ?   B . n 
D 1 202 LEU 202 173 ?   ?   ?   B . n 
D 1 203 LYS 203 174 ?   ?   ?   B . n 
D 1 204 LEU 204 175 ?   ?   ?   B . n 
D 1 205 ASP 205 176 ?   ?   ?   B . n 
D 1 206 PRO 206 177 ?   ?   ?   B . n 
D 1 207 THR 207 178 ?   ?   ?   B . n 
D 1 208 ILE 208 179 ?   ?   ?   B . n 
D 1 209 TYR 209 180 ?   ?   ?   B . n 
D 1 210 ASP 210 181 ?   ?   ?   B . n 
D 1 211 ALA 211 182 ?   ?   ?   B . n 
D 1 212 LEU 212 183 ?   ?   ?   B . n 
D 1 213 ILE 213 184 ?   ?   ?   B . n 
D 1 214 LYS 214 185 ?   ?   ?   B . n 
D 1 215 GLU 215 186 ?   ?   ?   B . n 
D 1 216 LYS 216 187 ?   ?   ?   B . n 
D 1 217 VAL 217 188 ?   ?   ?   B . n 
D 1 218 ALA 218 189 ?   ?   ?   B . n 
D 1 219 VAL 219 190 ?   ?   ?   B . n 
D 1 220 GLY 220 191 ?   ?   ?   B . n 
D 1 221 ASP 221 192 ?   ?   ?   B . n 
D 1 222 VAL 222 193 ?   ?   ?   B . n 
D 1 223 ILE 223 194 ?   ?   ?   B . n 
D 1 224 TYR 224 195 ?   ?   ?   B . n 
D 1 225 ILE 225 196 ?   ?   ?   B . n 
D 1 226 GLU 226 197 ?   ?   ?   B . n 
D 1 227 ALA 227 198 ?   ?   ?   B . n 
D 1 228 ASN 228 199 ?   ?   ?   B . n 
D 1 229 SER 229 200 ?   ?   ?   B . n 
D 1 230 GLY 230 201 ?   ?   ?   B . n 
D 1 231 ALA 231 202 ?   ?   ?   B . n 
D 1 232 VAL 232 203 ?   ?   ?   B . n 
D 1 233 LYS 233 204 ?   ?   ?   B . n 
D 1 234 ARG 234 205 ?   ?   ?   B . n 
D 1 235 VAL 235 206 ?   ?   ?   B . n 
D 1 236 GLY 236 207 ?   ?   ?   B . n 
D 1 237 ARG 237 208 ?   ?   ?   B . n 
D 1 238 SER 238 209 ?   ?   ?   B . n 
D 1 239 ASP 239 210 ?   ?   ?   B . n 
D 1 240 ALA 240 211 ?   ?   ?   B . n 
D 1 241 PHE 241 212 ?   ?   ?   B . n 
D 1 242 ALA 242 213 ?   ?   ?   B . n 
D 1 243 THR 243 214 ?   ?   ?   B . n 
D 1 244 GLU 244 215 ?   ?   ?   B . n 
D 1 245 PHE 245 216 ?   ?   ?   B . n 
D 1 246 ASP 246 217 ?   ?   ?   B . n 
D 1 247 LEU 247 218 ?   ?   ?   B . n 
D 1 248 GLU 248 219 ?   ?   ?   B . n 
D 1 249 ALA 249 220 ?   ?   ?   B . n 
D 1 250 GLU 250 221 ?   ?   ?   B . n 
D 1 251 GLU 251 222 ?   ?   ?   B . n 
D 1 252 TYR 252 223 ?   ?   ?   B . n 
D 1 253 VAL 253 224 ?   ?   ?   B . n 
D 1 254 PRO 254 225 ?   ?   ?   B . n 
D 1 255 LEU 255 226 ?   ?   ?   B . n 
D 1 256 PRO 256 227 ?   ?   ?   B . n 
D 1 257 LYS 257 228 ?   ?   ?   B . n 
D 1 258 GLY 258 229 ?   ?   ?   B . n 
D 1 259 GLU 259 230 ?   ?   ?   B . n 
D 1 260 VAL 260 231 ?   ?   ?   B . n 
D 1 261 HIS 261 232 ?   ?   ?   B . n 
D 1 262 LYS 262 233 ?   ?   ?   B . n 
D 1 263 LYS 263 234 ?   ?   ?   B . n 
D 1 264 LYS 264 235 ?   ?   ?   B . n 
D 1 265 GLU 265 236 ?   ?   ?   B . n 
D 1 266 ILE 266 237 ?   ?   ?   B . n 
D 1 267 VAL 267 238 238 VAL VAL B . n 
D 1 268 GLN 268 239 239 GLN GLN B . n 
D 1 269 ASP 269 240 240 ASP ASP B . n 
D 1 270 VAL 270 241 241 VAL VAL B . n 
D 1 271 THR 271 242 242 THR THR B . n 
D 1 272 LEU 272 243 243 LEU LEU B . n 
D 1 273 GLN 273 244 244 GLN GLN B . n 
D 1 274 ASP 274 245 245 ASP ASP B . n 
D 1 275 LEU 275 246 246 LEU LEU B . n 
D 1 276 ASP 276 247 247 ASP ASP B . n 
D 1 277 ALA 277 248 248 ALA ALA B . n 
D 1 278 ALA 278 249 249 ALA ALA B . n 
D 1 279 ASN 279 250 250 ASN ASN B . n 
D 1 280 ALA 280 251 251 ALA ALA B . n 
D 1 281 ARG 281 252 ?   ?   ?   B . n 
D 1 282 PRO 282 253 ?   ?   ?   B . n 
D 1 283 GLN 283 254 ?   ?   ?   B . n 
D 1 284 GLY 284 255 ?   ?   ?   B . n 
D 1 285 GLY 285 256 ?   ?   ?   B . n 
D 1 286 GLN 286 257 ?   ?   ?   B . n 
D 1 287 ASP 287 258 ?   ?   ?   B . n 
D 1 288 ILE 288 259 ?   ?   ?   B . n 
D 1 289 LEU 289 260 ?   ?   ?   B . n 
D 1 290 SER 290 261 ?   ?   ?   B . n 
D 1 291 LEU 291 262 ?   ?   ?   B . n 
D 1 292 MET 292 263 ?   ?   ?   B . n 
D 1 293 GLY 293 264 ?   ?   ?   B . n 
D 1 294 GLN 294 265 ?   ?   ?   B . n 
D 1 295 MET 295 266 ?   ?   ?   B . n 
D 1 296 MET 296 267 ?   ?   ?   B . n 
D 1 297 LYS 297 268 ?   ?   ?   B . n 
D 1 298 PRO 298 269 ?   ?   ?   B . n 
D 1 299 ARG 299 270 ?   ?   ?   B . n 
D 1 300 LYS 300 271 ?   ?   ?   B . n 
D 1 301 THR 301 272 ?   ?   ?   B . n 
D 1 302 GLU 302 273 ?   ?   ?   B . n 
D 1 303 ILE 303 274 ?   ?   ?   B . n 
D 1 304 THR 304 275 ?   ?   ?   B . n 
D 1 305 ASP 305 276 ?   ?   ?   B . n 
D 1 306 LYS 306 277 277 LYS LYS B . n 
D 1 307 LEU 307 278 278 LEU LEU B . n 
D 1 308 ARG 308 279 279 ARG ARG B . n 
D 1 309 GLN 309 280 280 GLN GLN B . n 
D 1 310 GLU 310 281 281 GLU GLU B . n 
D 1 311 ILE 311 282 282 ILE ILE B . n 
D 1 312 ASN 312 283 283 ASN ASN B . n 
D 1 313 LYS 313 284 284 LYS LYS B . n 
D 1 314 VAL 314 285 285 VAL VAL B . n 
D 1 315 VAL 315 286 286 VAL VAL B . n 
D 1 316 ASN 316 287 287 ASN ASN B . n 
D 1 317 ARG 317 288 288 ARG ARG B . n 
D 1 318 TYR 318 289 289 TYR TYR B . n 
D 1 319 ILE 319 290 290 ILE ILE B . n 
D 1 320 ASP 320 291 291 ASP ASP B . n 
D 1 321 GLU 321 292 292 GLU GLU B . n 
D 1 322 GLY 322 293 293 GLY GLY B . n 
D 1 323 VAL 323 294 294 VAL VAL B . n 
D 1 324 ALA 324 295 295 ALA ALA B . n 
D 1 325 GLU 325 296 296 GLU GLU B . n 
D 1 326 LEU 326 297 297 LEU LEU B . n 
D 1 327 VAL 327 298 298 VAL VAL B . n 
D 1 328 PRO 328 299 299 PRO PRO B . n 
D 1 329 GLY 329 300 300 GLY GLY B . n 
D 1 330 VAL 330 301 301 VAL VAL B . n 
D 1 331 LEU 331 302 302 LEU LEU B . n 
D 1 332 PHE 332 303 303 PHE PHE B . n 
D 1 333 ILE 333 304 304 ILE ILE B . n 
D 1 334 ASP 334 305 305 ASP ASP B . n 
D 1 335 GLU 335 306 306 GLU GLU B . n 
D 1 336 VAL 336 307 307 VAL VAL B . n 
D 1 337 HIS 337 308 308 HIS HIS B . n 
D 1 338 MET 338 309 309 MET MET B . n 
D 1 339 LEU 339 310 310 LEU LEU B . n 
D 1 340 ASP 340 311 311 ASP ASP B . n 
D 1 341 MET 341 312 312 MET MET B . n 
D 1 342 GLU 342 313 313 GLU GLU B . n 
D 1 343 CYS 343 314 314 CYS CYS B . n 
D 1 344 PHE 344 315 315 PHE PHE B . n 
D 1 345 SER 345 316 316 SER SER B . n 
D 1 346 TYR 346 317 317 TYR TYR B . n 
D 1 347 LEU 347 318 318 LEU LEU B . n 
D 1 348 ASN 348 319 319 ASN ASN B . n 
D 1 349 ARG 349 320 320 ARG ARG B . n 
D 1 350 ALA 350 321 321 ALA ALA B . n 
D 1 351 LEU 351 322 322 LEU LEU B . n 
D 1 352 GLU 352 323 323 GLU GLU B . n 
D 1 353 SER 353 324 324 SER SER B . n 
D 1 354 SER 354 325 325 SER SER B . n 
D 1 355 LEU 355 326 326 LEU LEU B . n 
D 1 356 SER 356 327 327 SER SER B . n 
D 1 357 PRO 357 328 328 PRO PRO B . n 
D 1 358 ILE 358 329 329 ILE ILE B . n 
D 1 359 VAL 359 330 330 VAL VAL B . n 
D 1 360 ILE 360 331 331 ILE ILE B . n 
D 1 361 PHE 361 332 332 PHE PHE B . n 
D 1 362 ALA 362 333 333 ALA ALA B . n 
D 1 363 THR 363 334 334 THR THR B . n 
D 1 364 ASN 364 335 335 ASN ASN B . n 
D 1 365 ARG 365 336 336 ARG ARG B . n 
D 1 366 GLY 366 337 337 GLY GLY B . n 
D 1 367 VAL 367 338 338 VAL VAL B . n 
D 1 368 CYS 368 339 339 CYS CYS B . n 
D 1 369 ASN 369 340 340 ASN ASN B . n 
D 1 370 VAL 370 341 341 VAL VAL B . n 
D 1 371 ARG 371 342 342 ARG ARG B . n 
D 1 372 GLY 372 343 343 GLY GLY B . n 
D 1 373 THR 373 344 344 THR THR B . n 
D 1 374 ASP 374 345 345 ASP ASP B . n 
D 1 375 MET 375 346 346 MET MET B . n 
D 1 376 PRO 376 347 347 PRO PRO B . n 
D 1 377 SER 377 348 348 SER SER B . n 
D 1 378 PRO 378 349 349 PRO PRO B . n 
D 1 379 HIS 379 350 350 HIS HIS B . n 
D 1 380 GLY 380 351 351 GLY GLY B . n 
D 1 381 VAL 381 352 352 VAL VAL B . n 
D 1 382 PRO 382 353 353 PRO PRO B . n 
D 1 383 ILE 383 354 354 ILE ILE B . n 
D 1 384 ASP 384 355 355 ASP ASP B . n 
D 1 385 LEU 385 356 356 LEU LEU B . n 
D 1 386 LEU 386 357 357 LEU LEU B . n 
D 1 387 ASP 387 358 358 ASP ASP B . n 
D 1 388 ARG 388 359 359 ARG ARG B . n 
D 1 389 LEU 389 360 360 LEU LEU B . n 
D 1 390 VAL 390 361 361 VAL VAL B . n 
D 1 391 ILE 391 362 362 ILE ILE B . n 
D 1 392 ILE 392 363 363 ILE ILE B . n 
D 1 393 ARG 393 364 364 ARG ARG B . n 
D 1 394 THR 394 365 365 THR THR B . n 
D 1 395 GLN 395 366 366 GLN GLN B . n 
D 1 396 ILE 396 367 367 ILE ILE B . n 
D 1 397 TYR 397 368 368 TYR TYR B . n 
D 1 398 ASP 398 369 369 ASP ASP B . n 
D 1 399 PRO 399 370 370 PRO PRO B . n 
D 1 400 SER 400 371 371 SER SER B . n 
D 1 401 GLU 401 372 372 GLU GLU B . n 
D 1 402 MET 402 373 373 MET MET B . n 
D 1 403 ILE 403 374 374 ILE ILE B . n 
D 1 404 GLN 404 375 375 GLN GLN B . n 
D 1 405 ILE 405 376 376 ILE ILE B . n 
D 1 406 ILE 406 377 377 ILE ILE B . n 
D 1 407 ALA 407 378 378 ALA ALA B . n 
D 1 408 ILE 408 379 379 ILE ILE B . n 
D 1 409 ARG 409 380 380 ARG ARG B . n 
D 1 410 ALA 410 381 381 ALA ALA B . n 
D 1 411 GLN 411 382 382 GLN GLN B . n 
D 1 412 VAL 412 383 383 VAL VAL B . n 
D 1 413 GLU 413 384 384 GLU GLU B . n 
D 1 414 GLU 414 385 385 GLU GLU B . n 
D 1 415 LEU 415 386 386 LEU LEU B . n 
D 1 416 THR 416 387 387 THR THR B . n 
D 1 417 VAL 417 388 388 VAL VAL B . n 
D 1 418 ASP 418 389 389 ASP ASP B . n 
D 1 419 GLU 419 390 390 GLU GLU B . n 
D 1 420 GLU 420 391 391 GLU GLU B . n 
D 1 421 CYS 421 392 392 CYS CYS B . n 
D 1 422 LEU 422 393 393 LEU LEU B . n 
D 1 423 VAL 423 394 394 VAL VAL B . n 
D 1 424 LEU 424 395 395 LEU LEU B . n 
D 1 425 LEU 425 396 396 LEU LEU B . n 
D 1 426 GLY 426 397 397 GLY GLY B . n 
D 1 427 GLU 427 398 398 GLU GLU B . n 
D 1 428 ILE 428 399 399 ILE ILE B . n 
D 1 429 GLY 429 400 400 GLY GLY B . n 
D 1 430 GLN 430 401 401 GLN GLN B . n 
D 1 431 ARG 431 402 402 ARG ARG B . n 
D 1 432 THR 432 403 403 THR THR B . n 
D 1 433 SER 433 404 404 SER SER B . n 
D 1 434 LEU 434 405 405 LEU LEU B . n 
D 1 435 ARG 435 406 406 ARG ARG B . n 
D 1 436 HIS 436 407 407 HIS HIS B . n 
D 1 437 ALA 437 408 408 ALA ALA B . n 
D 1 438 VAL 438 409 409 VAL VAL B . n 
D 1 439 GLN 439 410 410 GLN GLN B . n 
D 1 440 LEU 440 411 411 LEU LEU B . n 
D 1 441 LEU 441 412 412 LEU LEU B . n 
D 1 442 SER 442 413 413 SER SER B . n 
D 1 443 PRO 443 414 414 PRO PRO B . n 
D 1 444 ALA 444 415 415 ALA ALA B . n 
D 1 445 SER 445 416 416 SER SER B . n 
D 1 446 ILE 446 417 417 ILE ILE B . n 
D 1 447 VAL 447 418 418 VAL VAL B . n 
D 1 448 ALA 448 419 419 ALA ALA B . n 
D 1 449 LYS 449 420 420 LYS LYS B . n 
D 1 450 MET 450 421 421 MET MET B . n 
D 1 451 ASN 451 422 422 ASN ASN B . n 
D 1 452 GLY 452 423 423 GLY GLY B . n 
D 1 453 ARG 453 424 424 ARG ARG B . n 
D 1 454 ASP 454 425 425 ASP ASP B . n 
D 1 455 ASN 455 426 426 ASN ASN B . n 
D 1 456 ILE 456 427 427 ILE ILE B . n 
D 1 457 CYS 457 428 428 CYS CYS B . n 
D 1 458 LYS 458 429 429 LYS LYS B . n 
D 1 459 ALA 459 430 430 ALA ALA B . n 
D 1 460 ASP 460 431 431 ASP ASP B . n 
D 1 461 ILE 461 432 432 ILE ILE B . n 
D 1 462 GLU 462 433 433 GLU GLU B . n 
D 1 463 GLU 463 434 434 GLU GLU B . n 
D 1 464 VAL 464 435 435 VAL VAL B . n 
D 1 465 THR 465 436 436 THR THR B . n 
D 1 466 SER 466 437 437 SER SER B . n 
D 1 467 LEU 467 438 438 LEU LEU B . n 
D 1 468 TYR 468 439 439 TYR TYR B . n 
D 1 469 LEU 469 440 440 LEU LEU B . n 
D 1 470 ASP 470 441 441 ASP ASP B . n 
D 1 471 ALA 471 442 442 ALA ALA B . n 
D 1 472 LYS 472 443 443 LYS LYS B . n 
D 1 473 SER 473 444 444 SER SER B . n 
D 1 474 SER 474 445 445 SER SER B . n 
D 1 475 ALA 475 446 446 ALA ALA B . n 
D 1 476 LYS 476 447 447 LYS LYS B . n 
D 1 477 LEU 477 448 448 LEU LEU B . n 
D 1 478 LEU 478 449 449 LEU LEU B . n 
D 1 479 HIS 479 450 450 HIS HIS B . n 
D 1 480 GLU 480 451 451 GLU GLU B . n 
D 1 481 GLN 481 452 452 GLN GLN B . n 
D 1 482 GLN 482 453 ?   ?   ?   B . n 
D 1 483 GLU 483 454 ?   ?   ?   B . n 
D 1 484 LYS 484 455 ?   ?   ?   B . n 
D 1 485 TYR 485 456 ?   ?   ?   B . n 
D 1 486 ILE 486 457 ?   ?   ?   B . n 
D 1 487 SER 487 458 ?   ?   ?   B . n 
E 2 1   MET 1   -17 ?   ?   ?   F . n 
E 2 2   ALA 2   -16 ?   ?   ?   F . n 
E 2 3   ASP 3   -15 ?   ?   ?   F . n 
E 2 4   LEU 4   -14 ?   ?   ?   F . n 
E 2 5   ASN 5   -13 ?   ?   ?   F . n 
E 2 6   TRP 6   -12 ?   ?   ?   F . n 
E 2 7   ILE 7   -11 ?   ?   ?   F . n 
E 2 8   SER 8   -10 ?   ?   ?   F . n 
E 2 9   ALA 9   -9  ?   ?   ?   F . n 
E 2 10  GLY 10  -8  ?   ?   ?   F . n 
E 2 11  HIS 11  -7  ?   ?   ?   F . n 
E 2 12  ALA 12  -6  ?   ?   ?   F . n 
E 2 13  ILE 13  -5  ?   ?   ?   F . n 
E 2 14  ALA 14  -4  ?   ?   ?   F . n 
E 2 15  ASP 15  -3  ?   ?   ?   F . n 
E 2 16  VAL 16  -2  ?   ?   ?   F . n 
E 2 17  GLY 17  -1  ?   ?   ?   F . n 
E 2 18  THR 18  0   ?   ?   ?   F . n 
E 2 19  MET 19  1   ?   ?   ?   F . n 
E 2 20  ALA 20  2   ?   ?   ?   F . n 
E 2 21  GLU 21  3   ?   ?   ?   F . n 
E 2 22  LEU 22  4   ?   ?   ?   F . n 
E 2 23  LYS 23  5   ?   ?   ?   F . n 
E 2 24  LEU 24  6   ?   ?   ?   F . n 
E 2 25  SER 25  7   ?   ?   ?   F . n 
E 2 26  GLU 26  8   ?   ?   ?   F . n 
E 2 27  SER 27  9   ?   ?   ?   F . n 
E 2 28  ARG 28  10  ?   ?   ?   F . n 
E 2 29  ASP 29  11  ?   ?   ?   F . n 
E 2 30  LEU 30  12  ?   ?   ?   F . n 
E 2 31  THR 31  13  ?   ?   ?   F . n 
E 2 32  ARG 32  14  ?   ?   ?   F . n 
E 2 33  VAL 33  15  ?   ?   ?   F . n 
E 2 34  GLU 34  16  ?   ?   ?   F . n 
E 2 35  ARG 35  17  ?   ?   ?   F . n 
E 2 36  ILE 36  18  ?   ?   ?   F . n 
E 2 37  GLY 37  19  ?   ?   ?   F . n 
E 2 38  ALA 38  20  ?   ?   ?   F . n 
E 2 39  HIS 39  21  ?   ?   ?   F . n 
E 2 40  SER 40  22  ?   ?   ?   F . n 
E 2 41  HIS 41  23  ?   ?   ?   F . n 
E 2 42  ILE 42  24  ?   ?   ?   F . n 
E 2 43  ARG 43  25  ?   ?   ?   F . n 
E 2 44  GLY 44  26  ?   ?   ?   F . n 
E 2 45  LEU 45  27  ?   ?   ?   F . n 
E 2 46  GLY 46  28  ?   ?   ?   F . n 
E 2 47  LEU 47  29  ?   ?   ?   F . n 
E 2 48  ASP 48  30  ?   ?   ?   F . n 
E 2 49  SER 49  31  ?   ?   ?   F . n 
E 2 50  ALA 50  32  ?   ?   ?   F . n 
E 2 51  LEU 51  33  ?   ?   ?   F . n 
E 2 52  GLU 52  34  ?   ?   ?   F . n 
E 2 53  PRO 53  35  ?   ?   ?   F . n 
E 2 54  ARG 54  36  ?   ?   ?   F . n 
E 2 55  ALA 55  37  ?   ?   ?   F . n 
E 2 56  VAL 56  38  ?   ?   ?   F . n 
E 2 57  SER 57  39  ?   ?   ?   F . n 
E 2 58  GLU 58  40  ?   ?   ?   F . n 
E 2 59  GLY 59  41  ?   ?   ?   F . n 
E 2 60  MET 60  42  ?   ?   ?   F . n 
E 2 61  VAL 61  43  ?   ?   ?   F . n 
E 2 62  GLY 62  44  ?   ?   ?   F . n 
E 2 63  GLN 63  45  45  GLN GLN F . n 
E 2 64  VAL 64  46  46  VAL VAL F . n 
E 2 65  LYS 65  47  47  LYS LYS F . n 
E 2 66  ALA 66  48  48  ALA ALA F . n 
E 2 67  ARG 67  49  49  ARG ARG F . n 
E 2 68  LYS 68  50  50  LYS LYS F . n 
E 2 69  ALA 69  51  51  ALA ALA F . n 
E 2 70  ALA 70  52  52  ALA ALA F . n 
E 2 71  GLY 71  53  53  GLY GLY F . n 
E 2 72  VAL 72  54  54  VAL VAL F . n 
E 2 73  ILE 73  55  55  ILE ILE F . n 
E 2 74  LEU 74  56  56  LEU LEU F . n 
E 2 75  GLN 75  57  57  GLN GLN F . n 
E 2 76  MET 76  58  58  MET MET F . n 
E 2 77  ILE 77  59  59  ILE ILE F . n 
E 2 78  ARG 78  60  60  ARG ARG F . n 
E 2 79  GLU 79  61  61  GLU GLU F . n 
E 2 80  GLY 80  62  62  GLY GLY F . n 
E 2 81  LYS 81  63  63  LYS LYS F . n 
E 2 82  ILE 82  64  64  ILE ILE F . n 
E 2 83  ALA 83  65  65  ALA ALA F . n 
E 2 84  GLY 84  66  66  GLY GLY F . n 
E 2 85  ARG 85  67  67  ARG ARG F . n 
E 2 86  ALA 86  68  68  ALA ALA F . n 
E 2 87  ILE 87  69  69  ILE ILE F . n 
E 2 88  LEU 88  70  70  LEU LEU F . n 
E 2 89  ILE 89  71  71  ILE ILE F . n 
E 2 90  ALA 90  72  72  ALA ALA F . n 
E 2 91  GLY 91  73  73  GLY GLY F . n 
E 2 92  GLN 92  74  74  GLN GLN F . n 
E 2 93  PRO 93  75  75  PRO PRO F . n 
E 2 94  GLY 94  76  76  GLY GLY F . n 
E 2 95  THR 95  77  77  THR THR F . n 
E 2 96  GLY 96  78  78  GLY GLY F . n 
E 2 97  LYS 97  79  79  LYS LYS F . n 
E 2 98  THR 98  80  80  THR THR F . n 
E 2 99  ALA 99  81  81  ALA ALA F . n 
E 2 100 ILE 100 82  82  ILE ILE F . n 
E 2 101 ALA 101 83  83  ALA ALA F . n 
E 2 102 MET 102 84  84  MET MET F . n 
E 2 103 GLY 103 85  85  GLY GLY F . n 
E 2 104 MET 104 86  86  MET MET F . n 
E 2 105 ALA 105 87  87  ALA ALA F . n 
E 2 106 LYS 106 88  88  LYS LYS F . n 
E 2 107 SER 107 89  89  SER SER F . n 
E 2 108 LEU 108 90  90  LEU LEU F . n 
E 2 109 GLY 109 91  91  GLY GLY F . n 
E 2 110 LEU 110 92  92  LEU LEU F . n 
E 2 111 GLU 111 93  93  GLU GLU F . n 
E 2 112 THR 112 94  94  THR THR F . n 
E 2 113 PRO 113 95  95  PRO PRO F . n 
E 2 114 PHE 114 96  96  PHE PHE F . n 
E 2 115 ALA 115 97  97  ALA ALA F . n 
E 2 116 MET 116 98  98  MET MET F . n 
E 2 117 ILE 117 99  99  ILE ILE F . n 
E 2 118 ALA 118 100 100 ALA ALA F . n 
E 2 119 GLY 119 101 101 GLY GLY F . n 
E 2 120 SER 120 102 102 SER SER F . n 
E 2 121 GLU 121 103 103 GLU GLU F . n 
E 2 122 ILE 122 104 104 ILE ILE F . n 
E 2 123 PHE 123 105 105 PHE PHE F . n 
E 2 124 SER 124 106 106 SER SER F . n 
E 2 125 LEU 125 107 107 LEU LEU F . n 
E 2 126 GLU 126 108 108 GLU GLU F . n 
E 2 127 MET 127 109 109 MET MET F . n 
E 2 128 SER 128 110 110 SER SER F . n 
E 2 129 LYS 129 111 111 LYS LYS F . n 
E 2 130 THR 130 112 112 THR THR F . n 
E 2 131 GLU 131 113 113 GLU GLU F . n 
E 2 132 ALA 132 114 114 ALA ALA F . n 
E 2 133 LEU 133 115 115 LEU LEU F . n 
E 2 134 THR 134 116 116 THR THR F . n 
E 2 135 GLN 135 117 117 GLN GLN F . n 
E 2 136 SER 136 118 118 SER SER F . n 
E 2 137 PHE 137 119 119 PHE PHE F . n 
E 2 138 ARG 138 120 120 ARG ARG F . n 
E 2 139 LYS 139 121 121 LYS LYS F . n 
E 2 140 ALA 140 122 122 ALA ALA F . n 
E 2 141 ILE 141 123 123 ILE ILE F . n 
E 2 142 GLY 142 124 124 GLY GLY F . n 
E 2 143 VAL 143 125 125 VAL VAL F . n 
E 2 144 ARG 144 126 126 ARG ARG F . n 
E 2 145 ILE 145 127 ?   ?   ?   F . n 
E 2 146 LYS 146 128 ?   ?   ?   F . n 
E 2 147 GLU 147 129 ?   ?   ?   F . n 
E 2 148 GLU 148 130 ?   ?   ?   F . n 
E 2 149 THR 149 131 ?   ?   ?   F . n 
E 2 150 GLU 150 132 ?   ?   ?   F . n 
E 2 151 VAL 151 133 ?   ?   ?   F . n 
E 2 152 ILE 152 134 ?   ?   ?   F . n 
E 2 153 GLU 153 135 ?   ?   ?   F . n 
E 2 154 GLY 154 136 ?   ?   ?   F . n 
E 2 155 GLU 155 137 ?   ?   ?   F . n 
E 2 156 VAL 156 138 ?   ?   ?   F . n 
E 2 157 VAL 157 139 ?   ?   ?   F . n 
E 2 158 GLU 158 140 ?   ?   ?   F . n 
E 2 159 VAL 159 141 ?   ?   ?   F . n 
E 2 160 GLN 160 142 ?   ?   ?   F . n 
E 2 161 ILE 161 143 ?   ?   ?   F . n 
E 2 162 ASP 162 144 ?   ?   ?   F . n 
E 2 163 ARG 163 145 ?   ?   ?   F . n 
E 2 164 PRO 164 146 ?   ?   ?   F . n 
E 2 165 ALA 165 147 ?   ?   ?   F . n 
E 2 166 SER 166 148 ?   ?   ?   F . n 
E 2 167 SER 167 149 ?   ?   ?   F . n 
E 2 168 GLY 168 150 ?   ?   ?   F . n 
E 2 169 VAL 169 151 ?   ?   ?   F . n 
E 2 170 ALA 170 152 ?   ?   ?   F . n 
E 2 171 SER 171 153 ?   ?   ?   F . n 
E 2 172 LYS 172 154 ?   ?   ?   F . n 
E 2 173 SER 173 155 ?   ?   ?   F . n 
E 2 174 GLY 174 156 ?   ?   ?   F . n 
E 2 175 LYS 175 157 ?   ?   ?   F . n 
E 2 176 MET 176 158 ?   ?   ?   F . n 
E 2 177 THR 177 159 ?   ?   ?   F . n 
E 2 178 MET 178 160 ?   ?   ?   F . n 
E 2 179 LYS 179 161 ?   ?   ?   F . n 
E 2 180 THR 180 162 ?   ?   ?   F . n 
E 2 181 THR 181 163 ?   ?   ?   F . n 
E 2 182 ASP 182 164 ?   ?   ?   F . n 
E 2 183 MET 183 165 ?   ?   ?   F . n 
E 2 184 GLU 184 166 ?   ?   ?   F . n 
E 2 185 THR 185 167 ?   ?   ?   F . n 
E 2 186 VAL 186 168 ?   ?   ?   F . n 
E 2 187 TYR 187 169 ?   ?   ?   F . n 
E 2 188 ASP 188 170 ?   ?   ?   F . n 
E 2 189 MET 189 171 ?   ?   ?   F . n 
E 2 190 GLY 190 172 ?   ?   ?   F . n 
E 2 191 ALA 191 173 ?   ?   ?   F . n 
E 2 192 LYS 192 174 ?   ?   ?   F . n 
E 2 193 MET 193 175 ?   ?   ?   F . n 
E 2 194 ILE 194 176 ?   ?   ?   F . n 
E 2 195 GLU 195 177 ?   ?   ?   F . n 
E 2 196 ALA 196 178 ?   ?   ?   F . n 
E 2 197 LEU 197 179 ?   ?   ?   F . n 
E 2 198 ASN 198 180 ?   ?   ?   F . n 
E 2 199 LYS 199 181 ?   ?   ?   F . n 
E 2 200 GLU 200 182 ?   ?   ?   F . n 
E 2 201 LYS 201 183 ?   ?   ?   F . n 
E 2 202 VAL 202 184 ?   ?   ?   F . n 
E 2 203 GLN 203 185 ?   ?   ?   F . n 
E 2 204 SER 204 186 ?   ?   ?   F . n 
E 2 205 GLY 205 187 ?   ?   ?   F . n 
E 2 206 ASP 206 188 ?   ?   ?   F . n 
E 2 207 VAL 207 189 ?   ?   ?   F . n 
E 2 208 ILE 208 190 ?   ?   ?   F . n 
E 2 209 ALA 209 191 ?   ?   ?   F . n 
E 2 210 ILE 210 192 ?   ?   ?   F . n 
E 2 211 ASP 211 193 ?   ?   ?   F . n 
E 2 212 LYS 212 194 ?   ?   ?   F . n 
E 2 213 ALA 213 195 ?   ?   ?   F . n 
E 2 214 THR 214 196 ?   ?   ?   F . n 
E 2 215 GLY 215 197 ?   ?   ?   F . n 
E 2 216 LYS 216 198 ?   ?   ?   F . n 
E 2 217 ILE 217 199 ?   ?   ?   F . n 
E 2 218 THR 218 200 ?   ?   ?   F . n 
E 2 219 LYS 219 201 ?   ?   ?   F . n 
E 2 220 LEU 220 202 ?   ?   ?   F . n 
E 2 221 GLY 221 203 ?   ?   ?   F . n 
E 2 222 ARG 222 204 ?   ?   ?   F . n 
E 2 223 SER 223 205 ?   ?   ?   F . n 
E 2 224 PHE 224 206 ?   ?   ?   F . n 
E 2 225 SER 225 207 ?   ?   ?   F . n 
E 2 226 ARG 226 208 ?   ?   ?   F . n 
E 2 227 SER 227 209 ?   ?   ?   F . n 
E 2 228 ARG 228 210 ?   ?   ?   F . n 
E 2 229 ASP 229 211 ?   ?   ?   F . n 
E 2 230 TYR 230 212 ?   ?   ?   F . n 
E 2 231 ASP 231 213 ?   ?   ?   F . n 
E 2 232 ALA 232 214 ?   ?   ?   F . n 
E 2 233 MET 233 215 ?   ?   ?   F . n 
E 2 234 GLY 234 216 ?   ?   ?   F . n 
E 2 235 ALA 235 217 ?   ?   ?   F . n 
E 2 236 GLN 236 218 ?   ?   ?   F . n 
E 2 237 THR 237 219 ?   ?   ?   F . n 
E 2 238 LYS 238 220 ?   ?   ?   F . n 
E 2 239 PHE 239 221 ?   ?   ?   F . n 
E 2 240 VAL 240 222 ?   ?   ?   F . n 
E 2 241 GLN 241 223 ?   ?   ?   F . n 
E 2 242 CYS 242 224 ?   ?   ?   F . n 
E 2 243 PRO 243 225 ?   ?   ?   F . n 
E 2 244 GLU 244 226 ?   ?   ?   F . n 
E 2 245 GLY 245 227 ?   ?   ?   F . n 
E 2 246 GLU 246 228 ?   ?   ?   F . n 
E 2 247 LEU 247 229 ?   ?   ?   F . n 
E 2 248 GLN 248 230 ?   ?   ?   F . n 
E 2 249 LYS 249 231 ?   ?   ?   F . n 
E 2 250 ARG 250 232 ?   ?   ?   F . n 
E 2 251 LYS 251 233 ?   ?   ?   F . n 
E 2 252 GLU 252 234 ?   ?   ?   F . n 
E 2 253 VAL 253 235 ?   ?   ?   F . n 
E 2 254 VAL 254 236 ?   ?   ?   F . n 
E 2 255 HIS 255 237 ?   ?   ?   F . n 
E 2 256 CYS 256 238 238 CYS CYS F . n 
E 2 257 VAL 257 239 239 VAL VAL F . n 
E 2 258 THR 258 240 240 THR THR F . n 
E 2 259 LEU 259 241 241 LEU LEU F . n 
E 2 260 HIS 260 242 242 HIS HIS F . n 
E 2 261 GLU 261 243 243 GLU GLU F . n 
E 2 262 ILE 262 244 244 ILE ILE F . n 
E 2 263 ASP 263 245 245 ASP ASP F . n 
E 2 264 VAL 264 246 246 VAL VAL F . n 
E 2 265 ILE 265 247 247 ILE ILE F . n 
E 2 266 ASN 266 248 248 ASN ASN F . n 
E 2 267 SER 267 249 249 SER SER F . n 
E 2 268 ARG 268 250 ?   ?   ?   F . n 
E 2 269 THR 269 251 ?   ?   ?   F . n 
E 2 270 GLN 270 252 ?   ?   ?   F . n 
E 2 271 GLY 271 253 ?   ?   ?   F . n 
E 2 272 PHE 272 254 ?   ?   ?   F . n 
E 2 273 LEU 273 255 ?   ?   ?   F . n 
E 2 274 ALA 274 256 ?   ?   ?   F . n 
E 2 275 LEU 275 257 ?   ?   ?   F . n 
E 2 276 PHE 276 258 ?   ?   ?   F . n 
E 2 277 THR 277 259 ?   ?   ?   F . n 
E 2 278 GLY 278 260 ?   ?   ?   F . n 
E 2 279 ASP 279 261 ?   ?   ?   F . n 
E 2 280 THR 280 262 262 THR THR F . n 
E 2 281 GLY 281 263 263 GLY GLY F . n 
E 2 282 GLU 282 264 264 GLU GLU F . n 
E 2 283 ILE 283 265 265 ILE ILE F . n 
E 2 284 ARG 284 266 266 ARG ARG F . n 
E 2 285 SER 285 267 267 SER SER F . n 
E 2 286 GLU 286 268 268 GLU GLU F . n 
E 2 287 VAL 287 269 269 VAL VAL F . n 
E 2 288 ARG 288 270 270 ARG ARG F . n 
E 2 289 GLU 289 271 271 GLU GLU F . n 
E 2 290 GLN 290 272 272 GLN GLN F . n 
E 2 291 ILE 291 273 273 ILE ILE F . n 
E 2 292 ASP 292 274 274 ASP ASP F . n 
E 2 293 THR 293 275 275 THR THR F . n 
E 2 294 LYS 294 276 276 LYS LYS F . n 
E 2 295 VAL 295 277 277 VAL VAL F . n 
E 2 296 ALA 296 278 278 ALA ALA F . n 
E 2 297 GLU 297 279 279 GLU GLU F . n 
E 2 298 TRP 298 280 280 TRP TRP F . n 
E 2 299 ARG 299 281 281 ARG ARG F . n 
E 2 300 GLU 300 282 282 GLU GLU F . n 
E 2 301 GLU 301 283 283 GLU GLU F . n 
E 2 302 GLY 302 284 284 GLY GLY F . n 
E 2 303 LYS 303 285 285 LYS LYS F . n 
E 2 304 ALA 304 286 286 ALA ALA F . n 
E 2 305 GLU 305 287 287 GLU GLU F . n 
E 2 306 ILE 306 288 288 ILE ILE F . n 
E 2 307 VAL 307 289 289 VAL VAL F . n 
E 2 308 PRO 308 290 290 PRO PRO F . n 
E 2 309 GLY 309 291 291 GLY GLY F . n 
E 2 310 VAL 310 292 292 VAL VAL F . n 
E 2 311 LEU 311 293 293 LEU LEU F . n 
E 2 312 PHE 312 294 294 PHE PHE F . n 
E 2 313 ILE 313 295 295 ILE ILE F . n 
E 2 314 ASP 314 296 296 ASP ASP F . n 
E 2 315 GLU 315 297 297 GLU GLU F . n 
E 2 316 VAL 316 298 298 VAL VAL F . n 
E 2 317 HIS 317 299 299 HIS HIS F . n 
E 2 318 MET 318 300 300 MET MET F . n 
E 2 319 LEU 319 301 301 LEU LEU F . n 
E 2 320 ASP 320 302 302 ASP ASP F . n 
E 2 321 ILE 321 303 303 ILE ILE F . n 
E 2 322 GLU 322 304 304 GLU GLU F . n 
E 2 323 CYS 323 305 305 CYS CYS F . n 
E 2 324 PHE 324 306 306 PHE PHE F . n 
E 2 325 SER 325 307 307 SER SER F . n 
E 2 326 PHE 326 308 308 PHE PHE F . n 
E 2 327 LEU 327 309 309 LEU LEU F . n 
E 2 328 ASN 328 310 310 ASN ASN F . n 
E 2 329 ARG 329 311 311 ARG ARG F . n 
E 2 330 ALA 330 312 312 ALA ALA F . n 
E 2 331 LEU 331 313 313 LEU LEU F . n 
E 2 332 GLU 332 314 314 GLU GLU F . n 
E 2 333 ASN 333 315 315 ASN ASN F . n 
E 2 334 GLU 334 316 316 GLU GLU F . n 
E 2 335 MET 335 317 317 MET MET F . n 
E 2 336 SER 336 318 318 SER SER F . n 
E 2 337 PRO 337 319 319 PRO PRO F . n 
E 2 338 ILE 338 320 320 ILE ILE F . n 
E 2 339 LEU 339 321 321 LEU LEU F . n 
E 2 340 VAL 340 322 322 VAL VAL F . n 
E 2 341 VAL 341 323 323 VAL VAL F . n 
E 2 342 ALA 342 324 324 ALA ALA F . n 
E 2 343 THR 343 325 325 THR THR F . n 
E 2 344 ASN 344 326 326 ASN ASN F . n 
E 2 345 ARG 345 327 327 ARG ARG F . n 
E 2 346 GLY 346 328 328 GLY GLY F . n 
E 2 347 VAL 347 329 329 VAL VAL F . n 
E 2 348 THR 348 330 330 THR THR F . n 
E 2 349 THR 349 331 331 THR THR F . n 
E 2 350 ILE 350 332 332 ILE ILE F . n 
E 2 351 ARG 351 333 333 ARG ARG F . n 
E 2 352 GLY 352 334 334 GLY GLY F . n 
E 2 353 THR 353 335 335 THR THR F . n 
E 2 354 ASN 354 336 336 ASN ASN F . n 
E 2 355 GLN 355 337 337 GLN GLN F . n 
E 2 356 LYS 356 338 338 LYS LYS F . n 
E 2 357 SER 357 339 339 SER SER F . n 
E 2 358 PRO 358 340 340 PRO PRO F . n 
E 2 359 HIS 359 341 341 HIS HIS F . n 
E 2 360 GLY 360 342 342 GLY GLY F . n 
E 2 361 ILE 361 343 343 ILE ILE F . n 
E 2 362 PRO 362 344 344 PRO PRO F . n 
E 2 363 ILE 363 345 345 ILE ILE F . n 
E 2 364 ASP 364 346 346 ASP ASP F . n 
E 2 365 LEU 365 347 347 LEU LEU F . n 
E 2 366 LEU 366 348 348 LEU LEU F . n 
E 2 367 ASP 367 349 349 ASP ASP F . n 
E 2 368 ARG 368 350 350 ARG ARG F . n 
E 2 369 LEU 369 351 351 LEU LEU F . n 
E 2 370 LEU 370 352 352 LEU LEU F . n 
E 2 371 ILE 371 353 353 ILE ILE F . n 
E 2 372 ILE 372 354 354 ILE ILE F . n 
E 2 373 THR 373 355 355 THR THR F . n 
E 2 374 THR 374 356 356 THR THR F . n 
E 2 375 GLN 375 357 357 GLN GLN F . n 
E 2 376 PRO 376 358 358 PRO PRO F . n 
E 2 377 TYR 377 359 359 TYR TYR F . n 
E 2 378 THR 378 360 360 THR THR F . n 
E 2 379 ASP 379 361 361 ASP ASP F . n 
E 2 380 ASP 380 362 362 ASP ASP F . n 
E 2 381 ASP 381 363 363 ASP ASP F . n 
E 2 382 ILE 382 364 364 ILE ILE F . n 
E 2 383 ARG 383 365 365 ARG ARG F . n 
E 2 384 LYS 384 366 366 LYS LYS F . n 
E 2 385 ILE 385 367 367 ILE ILE F . n 
E 2 386 LEU 386 368 368 LEU LEU F . n 
E 2 387 GLU 387 369 369 GLU GLU F . n 
E 2 388 ILE 388 370 370 ILE ILE F . n 
E 2 389 ARG 389 371 371 ARG ARG F . n 
E 2 390 CYS 390 372 372 CYS CYS F . n 
E 2 391 GLN 391 373 373 GLN GLN F . n 
E 2 392 GLU 392 374 374 GLU GLU F . n 
E 2 393 GLU 393 375 375 GLU GLU F . n 
E 2 394 ASP 394 376 376 ASP ASP F . n 
E 2 395 VAL 395 377 377 VAL VAL F . n 
E 2 396 GLU 396 378 378 GLU GLU F . n 
E 2 397 MET 397 379 379 MET MET F . n 
E 2 398 ASN 398 380 380 ASN ASN F . n 
E 2 399 GLU 399 381 381 GLU GLU F . n 
E 2 400 GLU 400 382 382 GLU GLU F . n 
E 2 401 ALA 401 383 383 ALA ALA F . n 
E 2 402 LYS 402 384 384 LYS LYS F . n 
E 2 403 GLN 403 385 385 GLN GLN F . n 
E 2 404 LEU 404 386 386 LEU LEU F . n 
E 2 405 LEU 405 387 387 LEU LEU F . n 
E 2 406 THR 406 388 388 THR THR F . n 
E 2 407 LEU 407 389 389 LEU LEU F . n 
E 2 408 ILE 408 390 390 ILE ILE F . n 
E 2 409 GLY 409 391 391 GLY GLY F . n 
E 2 410 ARG 410 392 392 ARG ARG F . n 
E 2 411 ASP 411 393 393 ASP ASP F . n 
E 2 412 THR 412 394 394 THR THR F . n 
E 2 413 SER 413 395 395 SER SER F . n 
E 2 414 LEU 414 396 396 LEU LEU F . n 
E 2 415 ARG 415 397 397 ARG ARG F . n 
E 2 416 TYR 416 398 398 TYR TYR F . n 
E 2 417 ALA 417 399 399 ALA ALA F . n 
E 2 418 ILE 418 400 400 ILE ILE F . n 
E 2 419 HIS 419 401 401 HIS HIS F . n 
E 2 420 LEU 420 402 402 LEU LEU F . n 
E 2 421 ILE 421 403 403 ILE ILE F . n 
E 2 422 THR 422 404 404 THR THR F . n 
E 2 423 ALA 423 405 405 ALA ALA F . n 
E 2 424 ALA 424 406 406 ALA ALA F . n 
E 2 425 ALA 425 407 407 ALA ALA F . n 
E 2 426 LEU 426 408 408 LEU LEU F . n 
E 2 427 SER 427 409 409 SER SER F . n 
E 2 428 CYS 428 410 410 CYS CYS F . n 
E 2 429 GLN 429 411 411 GLN GLN F . n 
E 2 430 LYS 430 412 412 LYS LYS F . n 
E 2 431 ARG 431 413 413 ARG ARG F . n 
E 2 432 LYS 432 414 414 LYS LYS F . n 
E 2 433 GLY 433 415 415 GLY GLY F . n 
E 2 434 LYS 434 416 416 LYS LYS F . n 
E 2 435 VAL 435 417 417 VAL VAL F . n 
E 2 436 VAL 436 418 418 VAL VAL F . n 
E 2 437 GLU 437 419 419 GLU GLU F . n 
E 2 438 VAL 438 420 420 VAL VAL F . n 
E 2 439 GLU 439 421 421 GLU GLU F . n 
E 2 440 ASP 440 422 422 ASP ASP F . n 
E 2 441 ILE 441 423 423 ILE ILE F . n 
E 2 442 GLN 442 424 424 GLN GLN F . n 
E 2 443 ARG 443 425 425 ARG ARG F . n 
E 2 444 VAL 444 426 426 VAL VAL F . n 
E 2 445 TYR 445 427 427 TYR TYR F . n 
E 2 446 ARG 446 428 428 ARG ARG F . n 
E 2 447 LEU 447 429 429 LEU LEU F . n 
E 2 448 PHE 448 430 430 PHE PHE F . n 
E 2 449 LEU 449 431 431 LEU LEU F . n 
E 2 450 ASP 450 432 432 ASP ASP F . n 
E 2 451 VAL 451 433 433 VAL VAL F . n 
E 2 452 ARG 452 434 434 ARG ARG F . n 
E 2 453 ARG 453 435 435 ARG ARG F . n 
E 2 454 SER 454 436 436 SER SER F . n 
E 2 455 MET 455 437 437 MET MET F . n 
E 2 456 GLN 456 438 438 GLN GLN F . n 
E 2 457 TYR 457 439 439 TYR TYR F . n 
E 2 458 LEU 458 440 440 LEU LEU F . n 
E 2 459 VAL 459 441 441 VAL VAL F . n 
E 2 460 GLU 460 442 442 GLU GLU F . n 
E 2 461 TYR 461 443 443 TYR TYR F . n 
E 2 462 GLN 462 444 444 GLN GLN F . n 
E 2 463 SER 463 445 445 SER SER F . n 
E 2 464 GLN 464 446 446 GLN GLN F . n 
E 2 465 TYR 465 447 447 TYR TYR F . n 
E 2 466 MET 466 448 448 MET MET F . n 
E 2 467 PHE 467 449 ?   ?   ?   F . n 
E 2 468 SER 468 450 ?   ?   ?   F . n 
E 2 469 GLU 469 451 ?   ?   ?   F . n 
E 2 470 PRO 470 452 ?   ?   ?   F . n 
E 2 471 ILE 471 453 ?   ?   ?   F . n 
E 2 472 LYS 472 454 ?   ?   ?   F . n 
E 2 473 ASN 473 455 ?   ?   ?   F . n 
E 2 474 ASP 474 456 ?   ?   ?   F . n 
E 2 475 GLU 475 457 ?   ?   ?   F . n 
E 2 476 ALA 476 458 ?   ?   ?   F . n 
E 2 477 ALA 477 459 ?   ?   ?   F . n 
E 2 478 ALA 478 460 ?   ?   ?   F . n 
E 2 479 GLU 479 461 ?   ?   ?   F . n 
E 2 480 ASP 480 462 ?   ?   ?   F . n 
E 2 481 GLU 481 463 ?   ?   ?   F . n 
E 2 482 GLN 482 464 ?   ?   ?   F . n 
E 2 483 ASP 483 465 ?   ?   ?   F . n 
E 2 484 ALA 484 466 ?   ?   ?   F . n 
E 2 485 MET 485 467 ?   ?   ?   F . n 
E 2 486 GLN 486 468 ?   ?   ?   F . n 
E 2 487 ILE 487 469 ?   ?   ?   F . n 
F 2 1   MET 1   -17 ?   ?   ?   E . n 
F 2 2   ALA 2   -16 ?   ?   ?   E . n 
F 2 3   ASP 3   -15 ?   ?   ?   E . n 
F 2 4   LEU 4   -14 ?   ?   ?   E . n 
F 2 5   ASN 5   -13 ?   ?   ?   E . n 
F 2 6   TRP 6   -12 ?   ?   ?   E . n 
F 2 7   ILE 7   -11 ?   ?   ?   E . n 
F 2 8   SER 8   -10 ?   ?   ?   E . n 
F 2 9   ALA 9   -9  ?   ?   ?   E . n 
F 2 10  GLY 10  -8  ?   ?   ?   E . n 
F 2 11  HIS 11  -7  ?   ?   ?   E . n 
F 2 12  ALA 12  -6  ?   ?   ?   E . n 
F 2 13  ILE 13  -5  ?   ?   ?   E . n 
F 2 14  ALA 14  -4  ?   ?   ?   E . n 
F 2 15  ASP 15  -3  ?   ?   ?   E . n 
F 2 16  VAL 16  -2  ?   ?   ?   E . n 
F 2 17  GLY 17  -1  ?   ?   ?   E . n 
F 2 18  THR 18  0   ?   ?   ?   E . n 
F 2 19  MET 19  1   ?   ?   ?   E . n 
F 2 20  ALA 20  2   ?   ?   ?   E . n 
F 2 21  GLU 21  3   ?   ?   ?   E . n 
F 2 22  LEU 22  4   ?   ?   ?   E . n 
F 2 23  LYS 23  5   ?   ?   ?   E . n 
F 2 24  LEU 24  6   ?   ?   ?   E . n 
F 2 25  SER 25  7   ?   ?   ?   E . n 
F 2 26  GLU 26  8   ?   ?   ?   E . n 
F 2 27  SER 27  9   ?   ?   ?   E . n 
F 2 28  ARG 28  10  ?   ?   ?   E . n 
F 2 29  ASP 29  11  ?   ?   ?   E . n 
F 2 30  LEU 30  12  ?   ?   ?   E . n 
F 2 31  THR 31  13  ?   ?   ?   E . n 
F 2 32  ARG 32  14  ?   ?   ?   E . n 
F 2 33  VAL 33  15  ?   ?   ?   E . n 
F 2 34  GLU 34  16  ?   ?   ?   E . n 
F 2 35  ARG 35  17  ?   ?   ?   E . n 
F 2 36  ILE 36  18  ?   ?   ?   E . n 
F 2 37  GLY 37  19  ?   ?   ?   E . n 
F 2 38  ALA 38  20  ?   ?   ?   E . n 
F 2 39  HIS 39  21  ?   ?   ?   E . n 
F 2 40  SER 40  22  ?   ?   ?   E . n 
F 2 41  HIS 41  23  ?   ?   ?   E . n 
F 2 42  ILE 42  24  ?   ?   ?   E . n 
F 2 43  ARG 43  25  ?   ?   ?   E . n 
F 2 44  GLY 44  26  ?   ?   ?   E . n 
F 2 45  LEU 45  27  ?   ?   ?   E . n 
F 2 46  GLY 46  28  ?   ?   ?   E . n 
F 2 47  LEU 47  29  ?   ?   ?   E . n 
F 2 48  ASP 48  30  ?   ?   ?   E . n 
F 2 49  SER 49  31  ?   ?   ?   E . n 
F 2 50  ALA 50  32  ?   ?   ?   E . n 
F 2 51  LEU 51  33  ?   ?   ?   E . n 
F 2 52  GLU 52  34  ?   ?   ?   E . n 
F 2 53  PRO 53  35  ?   ?   ?   E . n 
F 2 54  ARG 54  36  ?   ?   ?   E . n 
F 2 55  ALA 55  37  ?   ?   ?   E . n 
F 2 56  VAL 56  38  ?   ?   ?   E . n 
F 2 57  SER 57  39  ?   ?   ?   E . n 
F 2 58  GLU 58  40  ?   ?   ?   E . n 
F 2 59  GLY 59  41  ?   ?   ?   E . n 
F 2 60  MET 60  42  ?   ?   ?   E . n 
F 2 61  VAL 61  43  ?   ?   ?   E . n 
F 2 62  GLY 62  44  ?   ?   ?   E . n 
F 2 63  GLN 63  45  45  GLN GLN E . n 
F 2 64  VAL 64  46  46  VAL VAL E . n 
F 2 65  LYS 65  47  47  LYS LYS E . n 
F 2 66  ALA 66  48  48  ALA ALA E . n 
F 2 67  ARG 67  49  49  ARG ARG E . n 
F 2 68  LYS 68  50  50  LYS LYS E . n 
F 2 69  ALA 69  51  51  ALA ALA E . n 
F 2 70  ALA 70  52  52  ALA ALA E . n 
F 2 71  GLY 71  53  53  GLY GLY E . n 
F 2 72  VAL 72  54  54  VAL VAL E . n 
F 2 73  ILE 73  55  55  ILE ILE E . n 
F 2 74  LEU 74  56  56  LEU LEU E . n 
F 2 75  GLN 75  57  57  GLN GLN E . n 
F 2 76  MET 76  58  58  MET MET E . n 
F 2 77  ILE 77  59  59  ILE ILE E . n 
F 2 78  ARG 78  60  60  ARG ARG E . n 
F 2 79  GLU 79  61  61  GLU GLU E . n 
F 2 80  GLY 80  62  62  GLY GLY E . n 
F 2 81  LYS 81  63  63  LYS LYS E . n 
F 2 82  ILE 82  64  64  ILE ILE E . n 
F 2 83  ALA 83  65  65  ALA ALA E . n 
F 2 84  GLY 84  66  66  GLY GLY E . n 
F 2 85  ARG 85  67  67  ARG ARG E . n 
F 2 86  ALA 86  68  68  ALA ALA E . n 
F 2 87  ILE 87  69  69  ILE ILE E . n 
F 2 88  LEU 88  70  70  LEU LEU E . n 
F 2 89  ILE 89  71  71  ILE ILE E . n 
F 2 90  ALA 90  72  72  ALA ALA E . n 
F 2 91  GLY 91  73  73  GLY GLY E . n 
F 2 92  GLN 92  74  74  GLN GLN E . n 
F 2 93  PRO 93  75  75  PRO PRO E . n 
F 2 94  GLY 94  76  76  GLY GLY E . n 
F 2 95  THR 95  77  77  THR THR E . n 
F 2 96  GLY 96  78  78  GLY GLY E . n 
F 2 97  LYS 97  79  79  LYS LYS E . n 
F 2 98  THR 98  80  80  THR THR E . n 
F 2 99  ALA 99  81  81  ALA ALA E . n 
F 2 100 ILE 100 82  82  ILE ILE E . n 
F 2 101 ALA 101 83  83  ALA ALA E . n 
F 2 102 MET 102 84  84  MET MET E . n 
F 2 103 GLY 103 85  85  GLY GLY E . n 
F 2 104 MET 104 86  86  MET MET E . n 
F 2 105 ALA 105 87  87  ALA ALA E . n 
F 2 106 LYS 106 88  88  LYS LYS E . n 
F 2 107 SER 107 89  89  SER SER E . n 
F 2 108 LEU 108 90  90  LEU LEU E . n 
F 2 109 GLY 109 91  91  GLY GLY E . n 
F 2 110 LEU 110 92  92  LEU LEU E . n 
F 2 111 GLU 111 93  93  GLU GLU E . n 
F 2 112 THR 112 94  94  THR THR E . n 
F 2 113 PRO 113 95  95  PRO PRO E . n 
F 2 114 PHE 114 96  96  PHE PHE E . n 
F 2 115 ALA 115 97  97  ALA ALA E . n 
F 2 116 MET 116 98  98  MET MET E . n 
F 2 117 ILE 117 99  99  ILE ILE E . n 
F 2 118 ALA 118 100 100 ALA ALA E . n 
F 2 119 GLY 119 101 101 GLY GLY E . n 
F 2 120 SER 120 102 102 SER SER E . n 
F 2 121 GLU 121 103 103 GLU GLU E . n 
F 2 122 ILE 122 104 104 ILE ILE E . n 
F 2 123 PHE 123 105 105 PHE PHE E . n 
F 2 124 SER 124 106 106 SER SER E . n 
F 2 125 LEU 125 107 107 LEU LEU E . n 
F 2 126 GLU 126 108 108 GLU GLU E . n 
F 2 127 MET 127 109 109 MET MET E . n 
F 2 128 SER 128 110 110 SER SER E . n 
F 2 129 LYS 129 111 111 LYS LYS E . n 
F 2 130 THR 130 112 112 THR THR E . n 
F 2 131 GLU 131 113 113 GLU GLU E . n 
F 2 132 ALA 132 114 114 ALA ALA E . n 
F 2 133 LEU 133 115 115 LEU LEU E . n 
F 2 134 THR 134 116 116 THR THR E . n 
F 2 135 GLN 135 117 117 GLN GLN E . n 
F 2 136 SER 136 118 118 SER SER E . n 
F 2 137 PHE 137 119 119 PHE PHE E . n 
F 2 138 ARG 138 120 120 ARG ARG E . n 
F 2 139 LYS 139 121 121 LYS LYS E . n 
F 2 140 ALA 140 122 122 ALA ALA E . n 
F 2 141 ILE 141 123 123 ILE ILE E . n 
F 2 142 GLY 142 124 124 GLY GLY E . n 
F 2 143 VAL 143 125 125 VAL VAL E . n 
F 2 144 ARG 144 126 126 ARG ARG E . n 
F 2 145 ILE 145 127 ?   ?   ?   E . n 
F 2 146 LYS 146 128 ?   ?   ?   E . n 
F 2 147 GLU 147 129 ?   ?   ?   E . n 
F 2 148 GLU 148 130 ?   ?   ?   E . n 
F 2 149 THR 149 131 ?   ?   ?   E . n 
F 2 150 GLU 150 132 ?   ?   ?   E . n 
F 2 151 VAL 151 133 ?   ?   ?   E . n 
F 2 152 ILE 152 134 ?   ?   ?   E . n 
F 2 153 GLU 153 135 ?   ?   ?   E . n 
F 2 154 GLY 154 136 ?   ?   ?   E . n 
F 2 155 GLU 155 137 ?   ?   ?   E . n 
F 2 156 VAL 156 138 ?   ?   ?   E . n 
F 2 157 VAL 157 139 ?   ?   ?   E . n 
F 2 158 GLU 158 140 ?   ?   ?   E . n 
F 2 159 VAL 159 141 ?   ?   ?   E . n 
F 2 160 GLN 160 142 ?   ?   ?   E . n 
F 2 161 ILE 161 143 ?   ?   ?   E . n 
F 2 162 ASP 162 144 ?   ?   ?   E . n 
F 2 163 ARG 163 145 ?   ?   ?   E . n 
F 2 164 PRO 164 146 ?   ?   ?   E . n 
F 2 165 ALA 165 147 ?   ?   ?   E . n 
F 2 166 SER 166 148 ?   ?   ?   E . n 
F 2 167 SER 167 149 ?   ?   ?   E . n 
F 2 168 GLY 168 150 ?   ?   ?   E . n 
F 2 169 VAL 169 151 ?   ?   ?   E . n 
F 2 170 ALA 170 152 ?   ?   ?   E . n 
F 2 171 SER 171 153 ?   ?   ?   E . n 
F 2 172 LYS 172 154 ?   ?   ?   E . n 
F 2 173 SER 173 155 ?   ?   ?   E . n 
F 2 174 GLY 174 156 ?   ?   ?   E . n 
F 2 175 LYS 175 157 ?   ?   ?   E . n 
F 2 176 MET 176 158 ?   ?   ?   E . n 
F 2 177 THR 177 159 ?   ?   ?   E . n 
F 2 178 MET 178 160 ?   ?   ?   E . n 
F 2 179 LYS 179 161 ?   ?   ?   E . n 
F 2 180 THR 180 162 ?   ?   ?   E . n 
F 2 181 THR 181 163 ?   ?   ?   E . n 
F 2 182 ASP 182 164 ?   ?   ?   E . n 
F 2 183 MET 183 165 ?   ?   ?   E . n 
F 2 184 GLU 184 166 ?   ?   ?   E . n 
F 2 185 THR 185 167 ?   ?   ?   E . n 
F 2 186 VAL 186 168 ?   ?   ?   E . n 
F 2 187 TYR 187 169 ?   ?   ?   E . n 
F 2 188 ASP 188 170 ?   ?   ?   E . n 
F 2 189 MET 189 171 ?   ?   ?   E . n 
F 2 190 GLY 190 172 ?   ?   ?   E . n 
F 2 191 ALA 191 173 ?   ?   ?   E . n 
F 2 192 LYS 192 174 ?   ?   ?   E . n 
F 2 193 MET 193 175 ?   ?   ?   E . n 
F 2 194 ILE 194 176 ?   ?   ?   E . n 
F 2 195 GLU 195 177 ?   ?   ?   E . n 
F 2 196 ALA 196 178 ?   ?   ?   E . n 
F 2 197 LEU 197 179 ?   ?   ?   E . n 
F 2 198 ASN 198 180 ?   ?   ?   E . n 
F 2 199 LYS 199 181 ?   ?   ?   E . n 
F 2 200 GLU 200 182 ?   ?   ?   E . n 
F 2 201 LYS 201 183 ?   ?   ?   E . n 
F 2 202 VAL 202 184 ?   ?   ?   E . n 
F 2 203 GLN 203 185 ?   ?   ?   E . n 
F 2 204 SER 204 186 ?   ?   ?   E . n 
F 2 205 GLY 205 187 ?   ?   ?   E . n 
F 2 206 ASP 206 188 ?   ?   ?   E . n 
F 2 207 VAL 207 189 ?   ?   ?   E . n 
F 2 208 ILE 208 190 ?   ?   ?   E . n 
F 2 209 ALA 209 191 ?   ?   ?   E . n 
F 2 210 ILE 210 192 ?   ?   ?   E . n 
F 2 211 ASP 211 193 ?   ?   ?   E . n 
F 2 212 LYS 212 194 ?   ?   ?   E . n 
F 2 213 ALA 213 195 ?   ?   ?   E . n 
F 2 214 THR 214 196 ?   ?   ?   E . n 
F 2 215 GLY 215 197 ?   ?   ?   E . n 
F 2 216 LYS 216 198 ?   ?   ?   E . n 
F 2 217 ILE 217 199 ?   ?   ?   E . n 
F 2 218 THR 218 200 ?   ?   ?   E . n 
F 2 219 LYS 219 201 ?   ?   ?   E . n 
F 2 220 LEU 220 202 ?   ?   ?   E . n 
F 2 221 GLY 221 203 ?   ?   ?   E . n 
F 2 222 ARG 222 204 ?   ?   ?   E . n 
F 2 223 SER 223 205 ?   ?   ?   E . n 
F 2 224 PHE 224 206 ?   ?   ?   E . n 
F 2 225 SER 225 207 ?   ?   ?   E . n 
F 2 226 ARG 226 208 ?   ?   ?   E . n 
F 2 227 SER 227 209 ?   ?   ?   E . n 
F 2 228 ARG 228 210 ?   ?   ?   E . n 
F 2 229 ASP 229 211 ?   ?   ?   E . n 
F 2 230 TYR 230 212 ?   ?   ?   E . n 
F 2 231 ASP 231 213 ?   ?   ?   E . n 
F 2 232 ALA 232 214 ?   ?   ?   E . n 
F 2 233 MET 233 215 ?   ?   ?   E . n 
F 2 234 GLY 234 216 ?   ?   ?   E . n 
F 2 235 ALA 235 217 ?   ?   ?   E . n 
F 2 236 GLN 236 218 ?   ?   ?   E . n 
F 2 237 THR 237 219 ?   ?   ?   E . n 
F 2 238 LYS 238 220 ?   ?   ?   E . n 
F 2 239 PHE 239 221 ?   ?   ?   E . n 
F 2 240 VAL 240 222 ?   ?   ?   E . n 
F 2 241 GLN 241 223 ?   ?   ?   E . n 
F 2 242 CYS 242 224 ?   ?   ?   E . n 
F 2 243 PRO 243 225 ?   ?   ?   E . n 
F 2 244 GLU 244 226 ?   ?   ?   E . n 
F 2 245 GLY 245 227 ?   ?   ?   E . n 
F 2 246 GLU 246 228 ?   ?   ?   E . n 
F 2 247 LEU 247 229 ?   ?   ?   E . n 
F 2 248 GLN 248 230 ?   ?   ?   E . n 
F 2 249 LYS 249 231 ?   ?   ?   E . n 
F 2 250 ARG 250 232 ?   ?   ?   E . n 
F 2 251 LYS 251 233 ?   ?   ?   E . n 
F 2 252 GLU 252 234 ?   ?   ?   E . n 
F 2 253 VAL 253 235 ?   ?   ?   E . n 
F 2 254 VAL 254 236 ?   ?   ?   E . n 
F 2 255 HIS 255 237 ?   ?   ?   E . n 
F 2 256 CYS 256 238 238 CYS CYS E . n 
F 2 257 VAL 257 239 239 VAL VAL E . n 
F 2 258 THR 258 240 240 THR THR E . n 
F 2 259 LEU 259 241 241 LEU LEU E . n 
F 2 260 HIS 260 242 242 HIS HIS E . n 
F 2 261 GLU 261 243 243 GLU GLU E . n 
F 2 262 ILE 262 244 244 ILE ILE E . n 
F 2 263 ASP 263 245 245 ASP ASP E . n 
F 2 264 VAL 264 246 246 VAL VAL E . n 
F 2 265 ILE 265 247 247 ILE ILE E . n 
F 2 266 ASN 266 248 248 ASN ASN E . n 
F 2 267 SER 267 249 249 SER SER E . n 
F 2 268 ARG 268 250 ?   ?   ?   E . n 
F 2 269 THR 269 251 ?   ?   ?   E . n 
F 2 270 GLN 270 252 ?   ?   ?   E . n 
F 2 271 GLY 271 253 ?   ?   ?   E . n 
F 2 272 PHE 272 254 ?   ?   ?   E . n 
F 2 273 LEU 273 255 ?   ?   ?   E . n 
F 2 274 ALA 274 256 ?   ?   ?   E . n 
F 2 275 LEU 275 257 ?   ?   ?   E . n 
F 2 276 PHE 276 258 ?   ?   ?   E . n 
F 2 277 THR 277 259 ?   ?   ?   E . n 
F 2 278 GLY 278 260 ?   ?   ?   E . n 
F 2 279 ASP 279 261 ?   ?   ?   E . n 
F 2 280 THR 280 262 262 THR THR E . n 
F 2 281 GLY 281 263 263 GLY GLY E . n 
F 2 282 GLU 282 264 264 GLU GLU E . n 
F 2 283 ILE 283 265 265 ILE ILE E . n 
F 2 284 ARG 284 266 266 ARG ARG E . n 
F 2 285 SER 285 267 267 SER SER E . n 
F 2 286 GLU 286 268 268 GLU GLU E . n 
F 2 287 VAL 287 269 269 VAL VAL E . n 
F 2 288 ARG 288 270 270 ARG ARG E . n 
F 2 289 GLU 289 271 271 GLU GLU E . n 
F 2 290 GLN 290 272 272 GLN GLN E . n 
F 2 291 ILE 291 273 273 ILE ILE E . n 
F 2 292 ASP 292 274 274 ASP ASP E . n 
F 2 293 THR 293 275 275 THR THR E . n 
F 2 294 LYS 294 276 276 LYS LYS E . n 
F 2 295 VAL 295 277 277 VAL VAL E . n 
F 2 296 ALA 296 278 278 ALA ALA E . n 
F 2 297 GLU 297 279 279 GLU GLU E . n 
F 2 298 TRP 298 280 280 TRP TRP E . n 
F 2 299 ARG 299 281 281 ARG ARG E . n 
F 2 300 GLU 300 282 282 GLU GLU E . n 
F 2 301 GLU 301 283 283 GLU GLU E . n 
F 2 302 GLY 302 284 284 GLY GLY E . n 
F 2 303 LYS 303 285 285 LYS LYS E . n 
F 2 304 ALA 304 286 286 ALA ALA E . n 
F 2 305 GLU 305 287 287 GLU GLU E . n 
F 2 306 ILE 306 288 288 ILE ILE E . n 
F 2 307 VAL 307 289 289 VAL VAL E . n 
F 2 308 PRO 308 290 290 PRO PRO E . n 
F 2 309 GLY 309 291 291 GLY GLY E . n 
F 2 310 VAL 310 292 292 VAL VAL E . n 
F 2 311 LEU 311 293 293 LEU LEU E . n 
F 2 312 PHE 312 294 294 PHE PHE E . n 
F 2 313 ILE 313 295 295 ILE ILE E . n 
F 2 314 ASP 314 296 296 ASP ASP E . n 
F 2 315 GLU 315 297 297 GLU GLU E . n 
F 2 316 VAL 316 298 298 VAL VAL E . n 
F 2 317 HIS 317 299 299 HIS HIS E . n 
F 2 318 MET 318 300 300 MET MET E . n 
F 2 319 LEU 319 301 301 LEU LEU E . n 
F 2 320 ASP 320 302 302 ASP ASP E . n 
F 2 321 ILE 321 303 303 ILE ILE E . n 
F 2 322 GLU 322 304 304 GLU GLU E . n 
F 2 323 CYS 323 305 305 CYS CYS E . n 
F 2 324 PHE 324 306 306 PHE PHE E . n 
F 2 325 SER 325 307 307 SER SER E . n 
F 2 326 PHE 326 308 308 PHE PHE E . n 
F 2 327 LEU 327 309 309 LEU LEU E . n 
F 2 328 ASN 328 310 310 ASN ASN E . n 
F 2 329 ARG 329 311 311 ARG ARG E . n 
F 2 330 ALA 330 312 312 ALA ALA E . n 
F 2 331 LEU 331 313 313 LEU LEU E . n 
F 2 332 GLU 332 314 314 GLU GLU E . n 
F 2 333 ASN 333 315 315 ASN ASN E . n 
F 2 334 GLU 334 316 316 GLU GLU E . n 
F 2 335 MET 335 317 317 MET MET E . n 
F 2 336 SER 336 318 318 SER SER E . n 
F 2 337 PRO 337 319 319 PRO PRO E . n 
F 2 338 ILE 338 320 320 ILE ILE E . n 
F 2 339 LEU 339 321 321 LEU LEU E . n 
F 2 340 VAL 340 322 322 VAL VAL E . n 
F 2 341 VAL 341 323 323 VAL VAL E . n 
F 2 342 ALA 342 324 324 ALA ALA E . n 
F 2 343 THR 343 325 325 THR THR E . n 
F 2 344 ASN 344 326 326 ASN ASN E . n 
F 2 345 ARG 345 327 327 ARG ARG E . n 
F 2 346 GLY 346 328 328 GLY GLY E . n 
F 2 347 VAL 347 329 329 VAL VAL E . n 
F 2 348 THR 348 330 330 THR THR E . n 
F 2 349 THR 349 331 331 THR THR E . n 
F 2 350 ILE 350 332 332 ILE ILE E . n 
F 2 351 ARG 351 333 333 ARG ARG E . n 
F 2 352 GLY 352 334 334 GLY GLY E . n 
F 2 353 THR 353 335 335 THR THR E . n 
F 2 354 ASN 354 336 336 ASN ASN E . n 
F 2 355 GLN 355 337 337 GLN GLN E . n 
F 2 356 LYS 356 338 338 LYS LYS E . n 
F 2 357 SER 357 339 339 SER SER E . n 
F 2 358 PRO 358 340 340 PRO PRO E . n 
F 2 359 HIS 359 341 341 HIS HIS E . n 
F 2 360 GLY 360 342 342 GLY GLY E . n 
F 2 361 ILE 361 343 343 ILE ILE E . n 
F 2 362 PRO 362 344 344 PRO PRO E . n 
F 2 363 ILE 363 345 345 ILE ILE E . n 
F 2 364 ASP 364 346 346 ASP ASP E . n 
F 2 365 LEU 365 347 347 LEU LEU E . n 
F 2 366 LEU 366 348 348 LEU LEU E . n 
F 2 367 ASP 367 349 349 ASP ASP E . n 
F 2 368 ARG 368 350 350 ARG ARG E . n 
F 2 369 LEU 369 351 351 LEU LEU E . n 
F 2 370 LEU 370 352 352 LEU LEU E . n 
F 2 371 ILE 371 353 353 ILE ILE E . n 
F 2 372 ILE 372 354 354 ILE ILE E . n 
F 2 373 THR 373 355 355 THR THR E . n 
F 2 374 THR 374 356 356 THR THR E . n 
F 2 375 GLN 375 357 357 GLN GLN E . n 
F 2 376 PRO 376 358 358 PRO PRO E . n 
F 2 377 TYR 377 359 359 TYR TYR E . n 
F 2 378 THR 378 360 360 THR THR E . n 
F 2 379 ASP 379 361 361 ASP ASP E . n 
F 2 380 ASP 380 362 362 ASP ASP E . n 
F 2 381 ASP 381 363 363 ASP ASP E . n 
F 2 382 ILE 382 364 364 ILE ILE E . n 
F 2 383 ARG 383 365 365 ARG ARG E . n 
F 2 384 LYS 384 366 366 LYS LYS E . n 
F 2 385 ILE 385 367 367 ILE ILE E . n 
F 2 386 LEU 386 368 368 LEU LEU E . n 
F 2 387 GLU 387 369 369 GLU GLU E . n 
F 2 388 ILE 388 370 370 ILE ILE E . n 
F 2 389 ARG 389 371 371 ARG ARG E . n 
F 2 390 CYS 390 372 372 CYS CYS E . n 
F 2 391 GLN 391 373 373 GLN GLN E . n 
F 2 392 GLU 392 374 374 GLU GLU E . n 
F 2 393 GLU 393 375 375 GLU GLU E . n 
F 2 394 ASP 394 376 376 ASP ASP E . n 
F 2 395 VAL 395 377 377 VAL VAL E . n 
F 2 396 GLU 396 378 378 GLU GLU E . n 
F 2 397 MET 397 379 379 MET MET E . n 
F 2 398 ASN 398 380 380 ASN ASN E . n 
F 2 399 GLU 399 381 381 GLU GLU E . n 
F 2 400 GLU 400 382 382 GLU GLU E . n 
F 2 401 ALA 401 383 383 ALA ALA E . n 
F 2 402 LYS 402 384 384 LYS LYS E . n 
F 2 403 GLN 403 385 385 GLN GLN E . n 
F 2 404 LEU 404 386 386 LEU LEU E . n 
F 2 405 LEU 405 387 387 LEU LEU E . n 
F 2 406 THR 406 388 388 THR THR E . n 
F 2 407 LEU 407 389 389 LEU LEU E . n 
F 2 408 ILE 408 390 390 ILE ILE E . n 
F 2 409 GLY 409 391 391 GLY GLY E . n 
F 2 410 ARG 410 392 392 ARG ARG E . n 
F 2 411 ASP 411 393 393 ASP ASP E . n 
F 2 412 THR 412 394 394 THR THR E . n 
F 2 413 SER 413 395 395 SER SER E . n 
F 2 414 LEU 414 396 396 LEU LEU E . n 
F 2 415 ARG 415 397 397 ARG ARG E . n 
F 2 416 TYR 416 398 398 TYR TYR E . n 
F 2 417 ALA 417 399 399 ALA ALA E . n 
F 2 418 ILE 418 400 400 ILE ILE E . n 
F 2 419 HIS 419 401 401 HIS HIS E . n 
F 2 420 LEU 420 402 402 LEU LEU E . n 
F 2 421 ILE 421 403 403 ILE ILE E . n 
F 2 422 THR 422 404 404 THR THR E . n 
F 2 423 ALA 423 405 405 ALA ALA E . n 
F 2 424 ALA 424 406 406 ALA ALA E . n 
F 2 425 ALA 425 407 407 ALA ALA E . n 
F 2 426 LEU 426 408 408 LEU LEU E . n 
F 2 427 SER 427 409 409 SER SER E . n 
F 2 428 CYS 428 410 410 CYS CYS E . n 
F 2 429 GLN 429 411 411 GLN GLN E . n 
F 2 430 LYS 430 412 412 LYS LYS E . n 
F 2 431 ARG 431 413 413 ARG ARG E . n 
F 2 432 LYS 432 414 414 LYS LYS E . n 
F 2 433 GLY 433 415 415 GLY GLY E . n 
F 2 434 LYS 434 416 416 LYS LYS E . n 
F 2 435 VAL 435 417 417 VAL VAL E . n 
F 2 436 VAL 436 418 418 VAL VAL E . n 
F 2 437 GLU 437 419 419 GLU GLU E . n 
F 2 438 VAL 438 420 420 VAL VAL E . n 
F 2 439 GLU 439 421 421 GLU GLU E . n 
F 2 440 ASP 440 422 422 ASP ASP E . n 
F 2 441 ILE 441 423 423 ILE ILE E . n 
F 2 442 GLN 442 424 424 GLN GLN E . n 
F 2 443 ARG 443 425 425 ARG ARG E . n 
F 2 444 VAL 444 426 426 VAL VAL E . n 
F 2 445 TYR 445 427 427 TYR TYR E . n 
F 2 446 ARG 446 428 428 ARG ARG E . n 
F 2 447 LEU 447 429 429 LEU LEU E . n 
F 2 448 PHE 448 430 430 PHE PHE E . n 
F 2 449 LEU 449 431 431 LEU LEU E . n 
F 2 450 ASP 450 432 432 ASP ASP E . n 
F 2 451 VAL 451 433 433 VAL VAL E . n 
F 2 452 ARG 452 434 434 ARG ARG E . n 
F 2 453 ARG 453 435 435 ARG ARG E . n 
F 2 454 SER 454 436 436 SER SER E . n 
F 2 455 MET 455 437 437 MET MET E . n 
F 2 456 GLN 456 438 438 GLN GLN E . n 
F 2 457 TYR 457 439 439 TYR TYR E . n 
F 2 458 LEU 458 440 440 LEU LEU E . n 
F 2 459 VAL 459 441 441 VAL VAL E . n 
F 2 460 GLU 460 442 442 GLU GLU E . n 
F 2 461 TYR 461 443 443 TYR TYR E . n 
F 2 462 GLN 462 444 444 GLN GLN E . n 
F 2 463 SER 463 445 445 SER SER E . n 
F 2 464 GLN 464 446 446 GLN GLN E . n 
F 2 465 TYR 465 447 447 TYR TYR E . n 
F 2 466 MET 466 448 448 MET MET E . n 
F 2 467 PHE 467 449 ?   ?   ?   E . n 
F 2 468 SER 468 450 ?   ?   ?   E . n 
F 2 469 GLU 469 451 ?   ?   ?   E . n 
F 2 470 PRO 470 452 ?   ?   ?   E . n 
F 2 471 ILE 471 453 ?   ?   ?   E . n 
F 2 472 LYS 472 454 ?   ?   ?   E . n 
F 2 473 ASN 473 455 ?   ?   ?   E . n 
F 2 474 ASP 474 456 ?   ?   ?   E . n 
F 2 475 GLU 475 457 ?   ?   ?   E . n 
F 2 476 ALA 476 458 ?   ?   ?   E . n 
F 2 477 ALA 477 459 ?   ?   ?   E . n 
F 2 478 ALA 478 460 ?   ?   ?   E . n 
F 2 479 GLU 479 461 ?   ?   ?   E . n 
F 2 480 ASP 480 462 ?   ?   ?   E . n 
F 2 481 GLU 481 463 ?   ?   ?   E . n 
F 2 482 GLN 482 464 ?   ?   ?   E . n 
F 2 483 ASP 483 465 ?   ?   ?   E . n 
F 2 484 ALA 484 466 ?   ?   ?   E . n 
F 2 485 MET 485 467 ?   ?   ?   E . n 
F 2 486 GLN 486 468 ?   ?   ?   E . n 
F 2 487 ILE 487 469 ?   ?   ?   E . n 
G 3 1   MET 1   -29 ?   ?   ?   G . n 
G 3 2   GLY 2   -28 ?   ?   ?   G . n 
G 3 3   SER 3   -27 ?   ?   ?   G . n 
G 3 4   SER 4   -26 ?   ?   ?   G . n 
G 3 5   HIS 5   -25 ?   ?   ?   G . n 
G 3 6   HIS 6   -24 ?   ?   ?   G . n 
G 3 7   HIS 7   -23 ?   ?   ?   G . n 
G 3 8   HIS 8   -22 ?   ?   ?   G . n 
G 3 9   HIS 9   -21 ?   ?   ?   G . n 
G 3 10  HIS 10  -20 ?   ?   ?   G . n 
G 3 11  HIS 11  -19 ?   ?   ?   G . n 
G 3 12  HIS 12  -18 ?   ?   ?   G . n 
G 3 13  HIS 13  -17 ?   ?   ?   G . n 
G 3 14  HIS 14  -16 ?   ?   ?   G . n 
G 3 15  MET 15  -15 ?   ?   ?   G . n 
G 3 16  THR 16  -14 ?   ?   ?   G . n 
G 3 17  ASP 17  -13 ?   ?   ?   G . n 
G 3 18  VAL 18  -12 ?   ?   ?   G . n 
G 3 19  THR 19  -11 ?   ?   ?   G . n 
G 3 20  ILE 20  -10 ?   ?   ?   G . n 
G 3 21  LYS 21  -9  ?   ?   ?   G . n 
G 3 22  GLY 22  -8  ?   ?   ?   G . n 
G 3 23  GLY 23  -7  ?   ?   ?   G . n 
G 3 24  GLU 24  -6  ?   ?   ?   G . n 
G 3 25  ASN 25  -5  ?   ?   ?   G . n 
G 3 26  LEU 26  -4  ?   ?   ?   G . n 
G 3 27  TYR 27  -3  ?   ?   ?   G . n 
G 3 28  PHE 28  -2  ?   ?   ?   G . n 
G 3 29  GLN 29  -1  ?   ?   ?   G . n 
G 3 30  GLY 30  0   ?   ?   ?   G . n 
G 3 31  MET 31  1   ?   ?   ?   G . n 
G 3 32  ALA 32  2   ?   ?   ?   G . n 
G 3 33  ARG 33  3   ?   ?   ?   G . n 
G 3 34  SER 34  4   ?   ?   ?   G . n 
G 3 35  PRO 35  5   ?   ?   ?   G . n 
G 3 36  SER 36  6   ?   ?   ?   G . n 
G 3 37  LYS 37  7   ?   ?   ?   G . n 
G 3 38  HIS 38  8   ?   ?   ?   G . n 
G 3 39  GLY 39  9   ?   ?   ?   G . n 
G 3 40  ARG 40  10  ?   ?   ?   G . n 
G 3 41  ASP 41  11  ?   ?   ?   G . n 
G 3 42  GLN 42  12  ?   ?   ?   G . n 
G 3 43  THR 43  13  ?   ?   ?   G . n 
G 3 44  GLN 44  14  ?   ?   ?   G . n 
G 3 45  ASP 45  15  ?   ?   ?   G . n 
G 3 46  PHE 46  16  ?   ?   ?   G . n 
G 3 47  GLN 47  17  ?   ?   ?   G . n 
G 3 48  GLY 48  18  ?   ?   ?   G . n 
G 3 49  PHE 49  19  ?   ?   ?   G . n 
G 3 50  PHE 50  20  ?   ?   ?   G . n 
G 3 51  ASN 51  21  ?   ?   ?   G . n 
G 3 52  ASP 52  22  ?   ?   ?   G . n 
G 3 53  LEU 53  23  ?   ?   ?   G . n 
G 3 54  GLN 54  24  ?   ?   ?   G . n 
G 3 55  ASP 55  25  ?   ?   ?   G . n 
G 3 56  TRP 56  26  ?   ?   ?   G . n 
G 3 57  GLU 57  27  ?   ?   ?   G . n 
G 3 58  LEU 58  28  ?   ?   ?   G . n 
G 3 59  SER 59  29  ?   ?   ?   G . n 
G 3 60  LEU 60  30  ?   ?   ?   G . n 
G 3 61  LYS 61  31  ?   ?   ?   G . n 
G 3 62  ASP 62  32  ?   ?   ?   G . n 
G 3 63  LYS 63  33  ?   ?   ?   G . n 
G 3 64  ASP 64  34  ?   ?   ?   G . n 
G 3 65  LYS 65  35  ?   ?   ?   G . n 
G 3 66  LYS 66  36  ?   ?   ?   G . n 
G 3 67  ILE 67  37  ?   ?   ?   G . n 
G 3 68  LYS 68  38  ?   ?   ?   G . n 
G 3 69  GLN 69  39  ?   ?   ?   G . n 
G 3 70  GLN 70  40  ?   ?   ?   G . n 
G 3 71  PRO 71  41  ?   ?   ?   G . n 
G 3 72  ALA 72  42  ?   ?   ?   G . n 
G 3 73  ASN 73  43  ?   ?   ?   G . n 
G 3 74  SER 74  44  ?   ?   ?   G . n 
G 3 75  SER 75  45  ?   ?   ?   G . n 
G 3 76  ASN 76  46  ?   ?   ?   G . n 
G 3 77  PRO 77  47  ?   ?   ?   G . n 
G 3 78  SER 78  48  ?   ?   ?   G . n 
G 3 79  SER 79  49  ?   ?   ?   G . n 
G 3 80  GLU 80  50  ?   ?   ?   G . n 
G 3 81  THR 81  51  ?   ?   ?   G . n 
G 3 82  PHE 82  52  ?   ?   ?   G . n 
G 3 83  ARG 83  53  ?   ?   ?   G . n 
G 3 84  PRO 84  54  ?   ?   ?   G . n 
G 3 85  SER 85  55  ?   ?   ?   G . n 
G 3 86  GLY 86  56  ?   ?   ?   G . n 
G 3 87  SER 87  57  ?   ?   ?   G . n 
G 3 88  GLY 88  58  ?   ?   ?   G . n 
G 3 89  LYS 89  59  ?   ?   ?   G . n 
G 3 90  TYR 90  60  ?   ?   ?   G . n 
G 3 91  ASP 91  61  ?   ?   ?   G . n 
G 3 92  PHE 92  62  ?   ?   ?   G . n 
G 3 93  ALA 93  63  ?   ?   ?   G . n 
G 3 94  LYS 94  64  ?   ?   ?   G . n 
G 3 95  LYS 95  65  ?   ?   ?   G . n 
G 3 96  TYR 96  66  ?   ?   ?   G . n 
G 3 97  ARG 97  67  ?   ?   ?   G . n 
G 3 98  SER 98  68  ?   ?   ?   G . n 
G 3 99  ILE 99  69  ?   ?   ?   G . n 
G 3 100 ARG 100 70  ?   ?   ?   G . n 
G 3 101 ASP 101 71  ?   ?   ?   G . n 
G 3 102 LEU 102 72  ?   ?   ?   G . n 
G 3 103 SER 103 73  ?   ?   ?   G . n 
G 3 104 SER 104 74  ?   ?   ?   G . n 
G 3 105 SER 105 75  ?   ?   ?   G . n 
G 3 106 LEU 106 76  ?   ?   ?   G . n 
G 3 107 ILE 107 77  ?   ?   ?   G . n 
G 3 108 GLY 108 78  ?   ?   ?   G . n 
G 3 109 GLU 109 79  ?   ?   ?   G . n 
G 3 110 SER 110 80  ?   ?   ?   G . n 
G 3 111 LEU 111 81  ?   ?   ?   G . n 
G 3 112 LEU 112 82  ?   ?   ?   G . n 
G 3 113 ASP 113 83  ?   ?   ?   G . n 
G 3 114 SER 114 84  ?   ?   ?   G . n 
G 3 115 SER 115 85  ?   ?   ?   G . n 
G 3 116 SER 116 86  ?   ?   ?   G . n 
G 3 117 GLU 117 87  ?   ?   ?   G . n 
G 3 118 LYS 118 88  ?   ?   ?   G . n 
G 3 119 GLU 119 89  ?   ?   ?   G . n 
G 3 120 GLN 120 90  ?   ?   ?   G . n 
G 3 121 GLY 121 91  ?   ?   ?   G . n 
G 3 122 ASN 122 92  ?   ?   ?   G . n 
G 3 123 GLU 123 93  ?   ?   ?   G . n 
G 3 124 PHE 124 94  ?   ?   ?   G . n 
G 3 125 PHE 125 95  ?   ?   ?   G . n 
G 3 126 LYS 126 96  ?   ?   ?   G . n 
G 3 127 GLN 127 97  ?   ?   ?   G . n 
G 3 128 LYS 128 98  ?   ?   ?   G . n 
G 3 129 LYS 129 99  ?   ?   ?   G . n 
G 3 130 PHE 130 100 ?   ?   ?   G . n 
G 3 131 ASN 131 101 ?   ?   ?   G . n 
G 3 132 GLU 132 102 ?   ?   ?   G . n 
G 3 133 ALA 133 103 ?   ?   ?   G . n 
G 3 134 ILE 134 104 ?   ?   ?   G . n 
G 3 135 ASP 135 105 ?   ?   ?   G . n 
G 3 136 CYS 136 106 ?   ?   ?   G . n 
G 3 137 TYR 137 107 ?   ?   ?   G . n 
G 3 138 SER 138 108 ?   ?   ?   G . n 
G 3 139 ARG 139 109 ?   ?   ?   G . n 
G 3 140 SER 140 110 ?   ?   ?   G . n 
G 3 141 ILE 141 111 ?   ?   ?   G . n 
G 3 142 ALA 142 112 ?   ?   ?   G . n 
G 3 143 LEU 143 113 ?   ?   ?   G . n 
G 3 144 SER 144 114 ?   ?   ?   G . n 
G 3 145 PRO 145 115 ?   ?   ?   G . n 
G 3 146 ASN 146 116 ?   ?   ?   G . n 
G 3 147 ALA 147 117 ?   ?   ?   G . n 
G 3 148 VAL 148 118 ?   ?   ?   G . n 
G 3 149 THR 149 119 ?   ?   ?   G . n 
G 3 150 TYR 150 120 ?   ?   ?   G . n 
G 3 151 ALA 151 121 ?   ?   ?   G . n 
G 3 152 ASN 152 122 ?   ?   ?   G . n 
G 3 153 ARG 153 123 ?   ?   ?   G . n 
G 3 154 ALA 154 124 ?   ?   ?   G . n 
G 3 155 MET 155 125 ?   ?   ?   G . n 
G 3 156 ALA 156 126 ?   ?   ?   G . n 
G 3 157 TYR 157 127 ?   ?   ?   G . n 
G 3 158 LEU 158 128 ?   ?   ?   G . n 
G 3 159 LYS 159 129 ?   ?   ?   G . n 
G 3 160 ILE 160 130 ?   ?   ?   G . n 
G 3 161 LYS 161 131 ?   ?   ?   G . n 
G 3 162 ARG 162 132 ?   ?   ?   G . n 
G 3 163 TYR 163 133 ?   ?   ?   G . n 
G 3 164 ARG 164 134 ?   ?   ?   G . n 
G 3 165 GLU 165 135 ?   ?   ?   G . n 
G 3 166 ALA 166 136 ?   ?   ?   G . n 
G 3 167 GLU 167 137 ?   ?   ?   G . n 
G 3 168 VAL 168 138 ?   ?   ?   G . n 
G 3 169 ASP 169 139 ?   ?   ?   G . n 
G 3 170 CYS 170 140 ?   ?   ?   G . n 
G 3 171 THR 171 141 ?   ?   ?   G . n 
G 3 172 GLU 172 142 ?   ?   ?   G . n 
G 3 173 ALA 173 143 ?   ?   ?   G . n 
G 3 174 LEU 174 144 ?   ?   ?   G . n 
G 3 175 ASN 175 145 ?   ?   ?   G . n 
G 3 176 LEU 176 146 ?   ?   ?   G . n 
G 3 177 ASP 177 147 ?   ?   ?   G . n 
G 3 178 ASP 178 148 ?   ?   ?   G . n 
G 3 179 ARG 179 149 ?   ?   ?   G . n 
G 3 180 TYR 180 150 ?   ?   ?   G . n 
G 3 181 ILE 181 151 ?   ?   ?   G . n 
G 3 182 LYS 182 152 ?   ?   ?   G . n 
G 3 183 ALA 183 153 ?   ?   ?   G . n 
G 3 184 TYR 184 154 ?   ?   ?   G . n 
G 3 185 SER 185 155 ?   ?   ?   G . n 
G 3 186 ARG 186 156 ?   ?   ?   G . n 
G 3 187 ARG 187 157 ?   ?   ?   G . n 
G 3 188 ALA 188 158 ?   ?   ?   G . n 
G 3 189 THR 189 159 ?   ?   ?   G . n 
G 3 190 ALA 190 160 ?   ?   ?   G . n 
G 3 191 ARG 191 161 ?   ?   ?   G . n 
G 3 192 LYS 192 162 ?   ?   ?   G . n 
G 3 193 GLU 193 163 ?   ?   ?   G . n 
G 3 194 LEU 194 164 ?   ?   ?   G . n 
G 3 195 GLY 195 165 ?   ?   ?   G . n 
G 3 196 MET 196 166 ?   ?   ?   G . n 
G 3 197 ILE 197 167 ?   ?   ?   G . n 
G 3 198 LYS 198 168 ?   ?   ?   G . n 
G 3 199 GLU 199 169 ?   ?   ?   G . n 
G 3 200 ALA 200 170 ?   ?   ?   G . n 
G 3 201 LYS 201 171 ?   ?   ?   G . n 
G 3 202 GLU 202 172 ?   ?   ?   G . n 
G 3 203 ASP 203 173 ?   ?   ?   G . n 
G 3 204 ALA 204 174 ?   ?   ?   G . n 
G 3 205 GLU 205 175 ?   ?   ?   G . n 
G 3 206 PHE 206 176 ?   ?   ?   G . n 
G 3 207 ALA 207 177 ?   ?   ?   G . n 
G 3 208 LEU 208 178 ?   ?   ?   G . n 
G 3 209 ARG 209 179 ?   ?   ?   G . n 
G 3 210 LEU 210 180 ?   ?   ?   G . n 
G 3 211 GLU 211 181 ?   ?   ?   G . n 
G 3 212 PRO 212 182 ?   ?   ?   G . n 
G 3 213 GLU 213 183 ?   ?   ?   G . n 
G 3 214 SER 214 184 ?   ?   ?   G . n 
G 3 215 GLN 215 185 ?   ?   ?   G . n 
G 3 216 GLU 216 186 ?   ?   ?   G . n 
G 3 217 LEU 217 187 ?   ?   ?   G . n 
G 3 218 LYS 218 188 ?   ?   ?   G . n 
G 3 219 LYS 219 189 ?   ?   ?   G . n 
G 3 220 GLN 220 190 ?   ?   ?   G . n 
G 3 221 TYR 221 191 ?   ?   ?   G . n 
G 3 222 ALA 222 192 ?   ?   ?   G . n 
G 3 223 ASP 223 193 ?   ?   ?   G . n 
G 3 224 ILE 224 194 ?   ?   ?   G . n 
G 3 225 LYS 225 195 ?   ?   ?   G . n 
G 3 226 SER 226 196 ?   ?   ?   G . n 
G 3 227 LEU 227 197 ?   ?   ?   G . n 
G 3 228 LEU 228 198 ?   ?   ?   G . n 
G 3 229 GLU 229 199 ?   ?   ?   G . n 
G 3 230 LYS 230 200 ?   ?   ?   G . n 
G 3 231 GLU 231 201 ?   ?   ?   G . n 
G 3 232 ILE 232 202 ?   ?   ?   G . n 
G 3 233 ILE 233 203 ?   ?   ?   G . n 
G 3 234 GLU 234 204 ?   ?   ?   G . n 
G 3 235 LYS 235 205 ?   ?   ?   G . n 
G 3 236 ALA 236 206 ?   ?   ?   G . n 
G 3 237 THR 237 207 ?   ?   ?   G . n 
G 3 238 GLY 238 208 ?   ?   ?   G . n 
G 3 239 ALA 239 209 ?   ?   ?   G . n 
G 3 240 MET 240 210 ?   ?   ?   G . n 
G 3 241 GLN 241 211 ?   ?   ?   G . n 
G 3 242 SER 242 212 ?   ?   ?   G . n 
G 3 243 THR 243 213 ?   ?   ?   G . n 
G 3 244 ALA 244 214 ?   ?   ?   G . n 
G 3 245 GLN 245 215 ?   ?   ?   G . n 
G 3 246 GLU 246 216 ?   ?   ?   G . n 
G 3 247 LEU 247 217 ?   ?   ?   G . n 
G 3 248 LEU 248 218 ?   ?   ?   G . n 
G 3 249 LYS 249 219 ?   ?   ?   G . n 
G 3 250 THR 250 220 ?   ?   ?   G . n 
G 3 251 SER 251 221 ?   ?   ?   G . n 
G 3 252 GLY 252 222 ?   ?   ?   G . n 
G 3 253 LEU 253 223 ?   ?   ?   G . n 
G 3 254 ASP 254 224 ?   ?   ?   G . n 
G 3 255 LYS 255 225 ?   ?   ?   G . n 
G 3 256 LYS 256 226 ?   ?   ?   G . n 
G 3 257 ILE 257 227 ?   ?   ?   G . n 
G 3 258 GLN 258 228 ?   ?   ?   G . n 
G 3 259 LYS 259 229 ?   ?   ?   G . n 
G 3 260 PRO 260 230 ?   ?   ?   G . n 
G 3 261 LYS 261 231 ?   ?   ?   G . n 
G 3 262 THR 262 232 ?   ?   ?   G . n 
G 3 263 GLU 263 233 ?   ?   ?   G . n 
G 3 264 MET 264 234 ?   ?   ?   G . n 
G 3 265 THR 265 235 ?   ?   ?   G . n 
G 3 266 SER 266 236 ?   ?   ?   G . n 
G 3 267 LYS 267 237 ?   ?   ?   G . n 
G 3 268 PRO 268 238 ?   ?   ?   G . n 
G 3 269 VAL 269 239 ?   ?   ?   G . n 
G 3 270 THR 270 240 ?   ?   ?   G . n 
G 3 271 LEU 271 241 ?   ?   ?   G . n 
G 3 272 VAL 272 242 ?   ?   ?   G . n 
G 3 273 ALA 273 243 ?   ?   ?   G . n 
G 3 274 LYS 274 244 ?   ?   ?   G . n 
G 3 275 THR 275 245 ?   ?   ?   G . n 
G 3 276 ASN 276 246 ?   ?   ?   G . n 
G 3 277 ARG 277 247 ?   ?   ?   G . n 
G 3 278 ASP 278 248 ?   ?   ?   G . n 
G 3 279 ILE 279 249 ?   ?   ?   G . n 
G 3 280 VAL 280 250 ?   ?   ?   G . n 
G 3 281 GLN 281 251 ?   ?   ?   G . n 
G 3 282 PRO 282 252 ?   ?   ?   G . n 
G 3 283 VAL 283 253 ?   ?   ?   G . n 
G 3 284 LEU 284 254 ?   ?   ?   G . n 
G 3 285 GLY 285 255 ?   ?   ?   G . n 
G 3 286 SER 286 256 ?   ?   ?   G . n 
G 3 287 ASN 287 257 ?   ?   ?   G . n 
G 3 288 GLU 288 258 ?   ?   ?   G . n 
G 3 289 SER 289 259 ?   ?   ?   G . n 
G 3 290 SER 290 260 ?   ?   ?   G . n 
G 3 291 GLY 291 261 ?   ?   ?   G . n 
G 3 292 LYS 292 262 ?   ?   ?   G . n 
G 3 293 LYS 293 263 ?   ?   ?   G . n 
G 3 294 LEU 294 264 ?   ?   ?   G . n 
G 3 295 ILE 295 265 ?   ?   ?   G . n 
G 3 296 GLU 296 266 ?   ?   ?   G . n 
G 3 297 ASN 297 267 ?   ?   ?   G . n 
G 3 298 ILE 298 268 ?   ?   ?   G . n 
G 3 299 GLN 299 269 ?   ?   ?   G . n 
G 3 300 PRO 300 270 ?   ?   ?   G . n 
G 3 301 GLU 301 271 ?   ?   ?   G . n 
G 3 302 GLU 302 272 ?   ?   ?   G . n 
G 3 303 LYS 303 273 ?   ?   ?   G . n 
G 3 304 SER 304 274 ?   ?   ?   G . n 
G 3 305 LYS 305 275 ?   ?   ?   G . n 
G 3 306 GLU 306 276 ?   ?   ?   G . n 
G 3 307 GLY 307 277 ?   ?   ?   G . n 
G 3 308 SER 308 278 ?   ?   ?   G . n 
G 3 309 MET 309 279 ?   ?   ?   G . n 
G 3 310 LYS 310 280 ?   ?   ?   G . n 
G 3 311 ILE 311 281 ?   ?   ?   G . n 
G 3 312 PRO 312 282 ?   ?   ?   G . n 
G 3 313 ALA 313 283 ?   ?   ?   G . n 
G 3 314 ILE 314 284 ?   ?   ?   G . n 
G 3 315 THR 315 285 ?   ?   ?   G . n 
G 3 316 GLU 316 286 ?   ?   ?   G . n 
G 3 317 ILE 317 287 ?   ?   ?   G . n 
G 3 318 LEU 318 288 ?   ?   ?   G . n 
G 3 319 ASP 319 289 ?   ?   ?   G . n 
G 3 320 SER 320 290 ?   ?   ?   G . n 
G 3 321 LYS 321 291 ?   ?   ?   G . n 
G 3 322 LYS 322 292 ?   ?   ?   G . n 
G 3 323 VAL 323 293 ?   ?   ?   G . n 
G 3 324 THR 324 294 ?   ?   ?   G . n 
G 3 325 PRO 325 295 ?   ?   ?   G . n 
G 3 326 GLY 326 296 ?   ?   ?   G . n 
G 3 327 SER 327 297 ?   ?   ?   G . n 
G 3 328 GLN 328 298 ?   ?   ?   G . n 
G 3 329 SER 329 299 ?   ?   ?   G . n 
G 3 330 TYR 330 300 ?   ?   ?   G . n 
G 3 331 GLU 331 301 ?   ?   ?   G . n 
G 3 332 LYS 332 302 ?   ?   ?   G . n 
G 3 333 GLU 333 303 ?   ?   ?   G . n 
G 3 334 ALA 334 304 ?   ?   ?   G . n 
G 3 335 LYS 335 305 ?   ?   ?   G . n 
G 3 336 PRO 336 306 ?   ?   ?   G . n 
G 3 337 SER 337 307 ?   ?   ?   G . n 
G 3 338 ASP 338 308 ?   ?   ?   G . n 
G 3 339 ARG 339 309 ?   ?   ?   G . n 
G 3 340 ASN 340 310 ?   ?   ?   G . n 
G 3 341 GLY 341 311 ?   ?   ?   G . n 
G 3 342 THR 342 312 ?   ?   ?   G . n 
G 3 343 GLN 343 313 ?   ?   ?   G . n 
G 3 344 PRO 344 314 ?   ?   ?   G . n 
G 3 345 SER 345 315 ?   ?   ?   G . n 
G 3 346 GLY 346 316 ?   ?   ?   G . n 
G 3 347 PRO 347 317 ?   ?   ?   G . n 
G 3 348 GLU 348 318 ?   ?   ?   G . n 
G 3 349 ASN 349 319 ?   ?   ?   G . n 
G 3 350 GLN 350 320 ?   ?   ?   G . n 
G 3 351 VAL 351 321 ?   ?   ?   G . n 
G 3 352 SER 352 322 ?   ?   ?   G . n 
G 3 353 LYS 353 323 ?   ?   ?   G . n 
G 3 354 GLN 354 324 ?   ?   ?   G . n 
G 3 355 LEU 355 325 ?   ?   ?   G . n 
G 3 356 GLU 356 326 ?   ?   ?   G . n 
G 3 357 LEU 357 327 ?   ?   ?   G . n 
G 3 358 LYS 358 328 ?   ?   ?   G . n 
G 3 359 PRO 359 329 ?   ?   ?   G . n 
G 3 360 SER 360 330 ?   ?   ?   G . n 
G 3 361 VAL 361 331 ?   ?   ?   G . n 
G 3 362 GLN 362 332 ?   ?   ?   G . n 
G 3 363 GLU 363 333 ?   ?   ?   G . n 
G 3 364 LEU 364 334 ?   ?   ?   G . n 
G 3 365 ALA 365 335 ?   ?   ?   G . n 
G 3 366 ALA 366 336 ?   ?   ?   G . n 
G 3 367 HIS 367 337 ?   ?   ?   G . n 
G 3 368 ALA 368 338 ?   ?   ?   G . n 
G 3 369 ALA 369 339 ?   ?   ?   G . n 
G 3 370 SER 370 340 ?   ?   ?   G . n 
G 3 371 LEU 371 341 ?   ?   ?   G . n 
G 3 372 ALA 372 342 ?   ?   ?   G . n 
G 3 373 MET 373 343 ?   ?   ?   G . n 
G 3 374 THR 374 344 ?   ?   ?   G . n 
G 3 375 GLU 375 345 ?   ?   ?   G . n 
G 3 376 ALA 376 346 ?   ?   ?   G . n 
G 3 377 SER 377 347 347 SER SER G . n 
G 3 378 LYS 378 348 348 LYS LYS G . n 
G 3 379 ASN 379 349 349 ASN ASN G . n 
G 3 380 ILE 380 350 350 ILE ILE G . n 
G 3 381 LYS 381 351 351 LYS LYS G . n 
G 3 382 THR 382 352 352 THR THR G . n 
G 3 383 PRO 383 353 353 PRO PRO G . n 
G 3 384 LYS 384 354 354 LYS LYS G . n 
G 3 385 SER 385 355 355 SER SER G . n 
G 3 386 ALA 386 356 356 ALA ALA G . n 
G 3 387 TYR 387 357 357 TYR TYR G . n 
G 3 388 GLU 388 358 358 GLU GLU G . n 
G 3 389 PHE 389 359 359 PHE PHE G . n 
G 3 390 GLU 390 360 360 GLU GLU G . n 
G 3 391 ASN 391 361 361 ASN ASN G . n 
G 3 392 SER 392 362 362 SER SER G . n 
G 3 393 TRP 393 363 363 TRP TRP G . n 
G 3 394 ARG 394 364 364 ARG ARG G . n 
G 3 395 SER 395 365 365 SER SER G . n 
G 3 396 PHE 396 366 366 PHE PHE G . n 
G 3 397 SER 397 367 367 SER SER G . n 
G 3 398 GLY 398 368 368 GLY GLY G . n 
G 3 399 ASP 399 369 369 ASP ASP G . n 
G 3 400 SER 400 370 370 SER SER G . n 
G 3 401 ALA 401 371 371 ALA ALA G . n 
G 3 402 LEU 402 372 372 LEU LEU G . n 
G 3 403 ARG 403 373 373 ARG ARG G . n 
G 3 404 SER 404 374 374 SER SER G . n 
G 3 405 GLN 405 375 375 GLN GLN G . n 
G 3 406 LEU 406 376 376 LEU LEU G . n 
G 3 407 LEU 407 377 377 LEU LEU G . n 
G 3 408 LYS 408 378 378 LYS LYS G . n 
G 3 409 VAL 409 379 379 VAL VAL G . n 
G 3 410 THR 410 380 380 THR THR G . n 
G 3 411 THR 411 381 381 THR THR G . n 
G 3 412 PRO 412 382 382 PRO PRO G . n 
G 3 413 SER 413 383 383 SER SER G . n 
G 3 414 SER 414 384 384 SER SER G . n 
G 3 415 LEU 415 385 385 LEU LEU G . n 
G 3 416 PRO 416 386 386 PRO PRO G . n 
G 3 417 GLN 417 387 387 GLN GLN G . n 
G 3 418 ILE 418 388 388 ILE ILE G . n 
G 3 419 PHE 419 389 389 PHE PHE G . n 
G 3 420 LYS 420 390 390 LYS LYS G . n 
G 3 421 ASN 421 391 391 ASN ASN G . n 
G 3 422 ALA 422 392 392 ALA ALA G . n 
G 3 423 LEU 423 393 393 LEU LEU G . n 
G 3 424 THR 424 394 394 THR THR G . n 
G 3 425 SER 425 395 395 SER SER G . n 
G 3 426 PRO 426 396 396 PRO PRO G . n 
G 3 427 VAL 427 397 397 VAL VAL G . n 
G 3 428 LEU 428 398 398 LEU LEU G . n 
G 3 429 VAL 429 399 399 VAL VAL G . n 
G 3 430 ASP 430 400 400 ASP ASP G . n 
G 3 431 ILE 431 401 401 ILE ILE G . n 
G 3 432 ILE 432 402 402 ILE ILE G . n 
G 3 433 LYS 433 403 403 LYS LYS G . n 
G 3 434 CYS 434 404 404 CYS CYS G . n 
G 3 435 VAL 435 405 405 VAL VAL G . n 
G 3 436 ALA 436 406 406 ALA ALA G . n 
G 3 437 SER 437 407 407 SER SER G . n 
G 3 438 PHE 438 408 408 PHE PHE G . n 
G 3 439 PHE 439 409 409 PHE PHE G . n 
G 3 440 THR 440 410 410 THR THR G . n 
G 3 441 GLU 441 411 411 GLU GLU G . n 
G 3 442 ASP 442 412 412 ASP ASP G . n 
G 3 443 MET 443 413 413 MET MET G . n 
G 3 444 ASP 444 414 414 ASP ASP G . n 
G 3 445 LEU 445 415 415 LEU LEU G . n 
G 3 446 ALA 446 416 416 ALA ALA G . n 
G 3 447 VAL 447 417 417 VAL VAL G . n 
G 3 448 LYS 448 418 418 LYS LYS G . n 
G 3 449 TYR 449 419 419 TYR TYR G . n 
G 3 450 ILE 450 420 420 ILE ILE G . n 
G 3 451 GLU 451 421 421 GLU GLU G . n 
G 3 452 ASN 452 422 422 ASN ASN G . n 
G 3 453 LEU 453 423 423 LEU LEU G . n 
G 3 454 THR 454 424 424 THR THR G . n 
G 3 455 LYS 455 425 425 LYS LYS G . n 
G 3 456 VAL 456 426 426 VAL VAL G . n 
G 3 457 PRO 457 427 427 PRO PRO G . n 
G 3 458 ARG 458 428 428 ARG ARG G . n 
G 3 459 PHE 459 429 429 PHE PHE G . n 
G 3 460 ASN 460 430 430 ASN ASN G . n 
G 3 461 MET 461 431 431 MET MET G . n 
G 3 462 LEU 462 432 432 LEU LEU G . n 
G 3 463 VAL 463 433 433 VAL VAL G . n 
G 3 464 MET 464 434 434 MET MET G . n 
G 3 465 CYS 465 435 435 CYS CYS G . n 
G 3 466 LEU 466 436 436 LEU LEU G . n 
G 3 467 THR 467 437 437 THR THR G . n 
G 3 468 SER 468 438 438 SER SER G . n 
G 3 469 THR 469 439 439 THR THR G . n 
G 3 470 GLU 470 440 440 GLU GLU G . n 
G 3 471 LYS 471 441 441 LYS LYS G . n 
G 3 472 ASN 472 442 442 ASN ASN G . n 
G 3 473 GLU 473 443 443 GLU GLU G . n 
G 3 474 LEU 474 444 444 LEU LEU G . n 
G 3 475 LEU 475 445 445 LEU LEU G . n 
G 3 476 LYS 476 446 446 LYS LYS G . n 
G 3 477 ILE 477 447 447 ILE ILE G . n 
G 3 478 TRP 478 448 448 TRP TRP G . n 
G 3 479 GLU 479 449 449 GLU GLU G . n 
G 3 480 ASP 480 450 450 ASP ASP G . n 
G 3 481 VAL 481 451 451 VAL VAL G . n 
G 3 482 PHE 482 452 452 PHE PHE G . n 
G 3 483 CYS 483 453 453 CYS CYS G . n 
G 3 484 ASN 484 454 454 ASN ASN G . n 
G 3 485 LYS 485 455 455 LYS LYS G . n 
G 3 486 ALA 486 456 456 ALA ALA G . n 
G 3 487 THR 487 457 457 THR THR G . n 
G 3 488 PRO 488 458 458 PRO PRO G . n 
G 3 489 MET 489 459 459 MET MET G . n 
G 3 490 GLU 490 460 460 GLU GLU G . n 
G 3 491 TYR 491 461 461 TYR TYR G . n 
G 3 492 ALA 492 462 462 ALA ALA G . n 
G 3 493 GLU 493 463 463 GLU GLU G . n 
G 3 494 VAL 494 464 464 VAL VAL G . n 
G 3 495 LEU 495 465 465 LEU LEU G . n 
G 3 496 ASP 496 466 466 ASP ASP G . n 
G 3 497 LYS 497 467 467 LYS LYS G . n 
G 3 498 LEU 498 468 468 LEU LEU G . n 
G 3 499 ARG 499 469 469 ARG ARG G . n 
G 3 500 SER 500 470 470 SER SER G . n 
G 3 501 ARG 501 471 471 ARG ARG G . n 
G 3 502 TYR 502 472 472 TYR TYR G . n 
G 3 503 CYS 503 473 473 CYS CYS G . n 
G 3 504 LEU 504 474 474 LEU LEU G . n 
G 3 505 LYS 505 475 475 LYS LYS G . n 
G 3 506 GLN 506 476 476 GLN GLN G . n 
G 3 507 LEU 507 477 ?   ?   ?   G . n 
G 3 508 GLU 508 478 ?   ?   ?   G . n 
G 3 509 VAL 509 479 ?   ?   ?   G . n 
G 3 510 LEU 510 480 ?   ?   ?   G . n 
G 3 511 PHE 511 481 ?   ?   ?   G . n 
G 3 512 GLN 512 482 ?   ?   ?   G . n 
G 3 513 GLY 513 483 ?   ?   ?   G . n 
G 3 514 PRO 514 484 ?   ?   ?   G . n 
G 3 515 TRP 515 485 ?   ?   ?   G . n 
G 3 516 SER 516 486 ?   ?   ?   G . n 
G 3 517 HIS 517 487 ?   ?   ?   G . n 
G 3 518 PRO 518 488 ?   ?   ?   G . n 
G 3 519 GLN 519 489 ?   ?   ?   G . n 
G 3 520 PHE 520 490 ?   ?   ?   G . n 
G 3 521 GLU 521 491 ?   ?   ?   G . n 
G 3 522 LYS 522 492 ?   ?   ?   G . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ADP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ADP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
H 4 ADP 1 501 501 ADP ADP A . 
I 4 ADP 1 501 501 ADP ADP C . 
J 4 ADP 1 501 501 ADP ADP B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 C ARG 406 ? CG  ? C ARG 435 CG  
2 1 Y 1 C ARG 406 ? CD  ? C ARG 435 CD  
3 1 Y 1 C ARG 406 ? NE  ? C ARG 435 NE  
4 1 Y 1 C ARG 406 ? CZ  ? C ARG 435 CZ  
5 1 Y 1 C ARG 406 ? NH1 ? C ARG 435 NH1 
6 1 Y 1 C ARG 406 ? NH2 ? C ARG 435 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EQ2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EQ2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EQ2 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9EQ2 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 14810 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.977 ? 19997 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 7.734 ? 2053  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.050 ? 2388  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.007 ? 2549  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9EQ2 
_struct.title                        'Arabidopsis thaliana R2T complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EQ2 
_struct_keywords.text            'RUVBL1, RUVBL2, R2TP, HSP90, Chaperone' 
_struct_keywords.pdbx_keywords   CHAPERONE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP RIN1_ARATH   Q9FMR9 ? 1 
;MEKVKIEEIQSTAKKQRIATHTHIKGLGLEPTGIPIKLAAGFVGQLEAREAAGLVVDMIKQKKMAGKALLLAGPPGTGKT
ALALGISQELGSKVPFCPMVGSEVYSSEVKKTEVLMENFRRAIGLRIKETKEVYEGEVTELSPEETESLTGGYGKSISHV
VITLKTVKGTKHLKLDPTIYDALIKEKVAVGDVIYIEANSGAVKRVGRSDAFATEFDLEAEEYVPLPKGEVHKKKEIVQD
VTLQDLDAANARPQGGQDILSLMGQMMKPRKTEITDKLRQEINKVVNRYIDEGVAELVPGVLFIDEVHMLDMECFSYLNR
ALESSLSPIVIFATNRGVCNVRGTDMPSPHGVPIDLLDRLVIIRTQIYDPSEMIQIIAIRAQVEELTVDEECLVLLGEIG
QRTSLRHAVQLLSPASIVAKMNGRDNICKADIEEVTSLYLDAKSSAKLLHEQQEKYIS
;
1 
2 UNP Q9FJW0_ARATH Q9FJW0 ? 2 
;MAELKLSESRDLTRVERIGAHSHIRGLGLDSALEPRAVSEGMVGQVKARKAAGVILQMIREGKIAGRAILIAGQPGTGKT
AIAMGMAKSLGLETPFAMIAGSEIFSLEMSKTEALTQSFRKAIGVRIKEETEVIEGEVVEVQIDRPASSGVASKSGKMTM
KTTDMETVYDMGAKMIEALNKEKVQSGDVIAIDKATGKITKLGRSFSRSRDYDAMGAQTKFVQCPEGELQKRKEVVHCVT
LHEIDVINSRTQGFLALFTGDTGEIRSEVREQIDTKVAEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALENEMSPI
LVVATNRGVTTIRGTNQKSPHGIPIDLLDRLLIITTQPYTDDDIRKILEIRCQEEDVEMNEEAKQLLTLIGRDTSLRYAI
HLITAAALSCQKRKGKVVEVEDIQRVYRLFLDVRRSMQYLVEYQSQYMFSEPIKNDEAAAEDEQDAMQI
;
1 
3 UNP Q5XF05_ARATH Q5XF05 ? 3 
;MARSPSKHGRDQTQDFQGFFNDLQDWELSLKDKDKKIKQQPANSSNPSSETFRPSGSGKYDFAKKYRSIRDLSSSLIGES
LLDSSSEKEQGNEFFKQKKFNEAIDCYSRSIALSPNAVTYANRAMAYLKIKRYREAEVDCTEALNLDDRYIKAYSRRATA
RKELGMIKEAKEDAEFALRLEPESQELKKQYADIKSLLEKEIIEKATGAMQSTAQELLKTSGLDKKIQKPKTEMTSKPVT
LVAKTNRDIVQPVLGSNESSGKKLIENIQPEEKSKEGSMKIPAITEILDSKKVTPGSQSYEKEAKPSDRNGTQPSGPENQ
VSKQLELKPSVQELAAHAASLAMTEASKNIKTPKSAYEFENSWRSFSGDSALRSQLLKVTTPSSLPQIFKNALTSPVLVD
IIKCVASFFTEDMDLAVKYIENLTKVPRFNMLVMCLTSTEKNELLKIWEDVFCNKATPMEYAEVLDKLRSRYCLKQ
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9EQ2 A 30 ? 487 ? Q9FMR9 1 ? 458 ? 1 458 
2 2 9EQ2 D 19 ? 487 ? Q9FJW0 1 ? 469 ? 1 469 
3 1 9EQ2 C 30 ? 487 ? Q9FMR9 1 ? 458 ? 1 458 
4 1 9EQ2 B 30 ? 487 ? Q9FMR9 1 ? 458 ? 1 458 
5 2 9EQ2 F 19 ? 487 ? Q9FJW0 1 ? 469 ? 1 469 
6 2 9EQ2 E 19 ? 487 ? Q9FJW0 1 ? 469 ? 1 469 
7 3 9EQ2 G 31 ? 506 ? Q5XF05 1 ? 476 ? 1 476 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9EQ2 MET A 1   ? UNP Q9FMR9 ? ? 'initiating methionine' -28 1   
1 9EQ2 GLY A 2   ? UNP Q9FMR9 ? ? 'expression tag'        -27 2   
1 9EQ2 SER A 3   ? UNP Q9FMR9 ? ? 'expression tag'        -26 3   
1 9EQ2 SER A 4   ? UNP Q9FMR9 ? ? 'expression tag'        -25 4   
1 9EQ2 HIS A 5   ? UNP Q9FMR9 ? ? 'expression tag'        -24 5   
1 9EQ2 HIS A 6   ? UNP Q9FMR9 ? ? 'expression tag'        -23 6   
1 9EQ2 HIS A 7   ? UNP Q9FMR9 ? ? 'expression tag'        -22 7   
1 9EQ2 HIS A 8   ? UNP Q9FMR9 ? ? 'expression tag'        -21 8   
1 9EQ2 HIS A 9   ? UNP Q9FMR9 ? ? 'expression tag'        -20 9   
1 9EQ2 HIS A 10  ? UNP Q9FMR9 ? ? 'expression tag'        -19 10  
1 9EQ2 HIS A 11  ? UNP Q9FMR9 ? ? 'expression tag'        -18 11  
1 9EQ2 HIS A 12  ? UNP Q9FMR9 ? ? 'expression tag'        -17 12  
1 9EQ2 SER A 13  ? UNP Q9FMR9 ? ? 'expression tag'        -16 13  
1 9EQ2 SER A 14  ? UNP Q9FMR9 ? ? 'expression tag'        -15 14  
1 9EQ2 GLY A 15  ? UNP Q9FMR9 ? ? 'expression tag'        -14 15  
1 9EQ2 GLU A 16  ? UNP Q9FMR9 ? ? 'expression tag'        -13 16  
1 9EQ2 ASN A 17  ? UNP Q9FMR9 ? ? 'expression tag'        -12 17  
1 9EQ2 LEU A 18  ? UNP Q9FMR9 ? ? 'expression tag'        -11 18  
1 9EQ2 TYR A 19  ? UNP Q9FMR9 ? ? 'expression tag'        -10 19  
1 9EQ2 PHE A 20  ? UNP Q9FMR9 ? ? 'expression tag'        -9  20  
1 9EQ2 GLN A 21  ? UNP Q9FMR9 ? ? 'expression tag'        -8  21  
1 9EQ2 GLY A 22  ? UNP Q9FMR9 ? ? 'expression tag'        -7  22  
1 9EQ2 SER A 23  ? UNP Q9FMR9 ? ? 'expression tag'        -6  23  
1 9EQ2 HIS A 24  ? UNP Q9FMR9 ? ? 'expression tag'        -5  24  
1 9EQ2 MET A 25  ? UNP Q9FMR9 ? ? 'expression tag'        -4  25  
1 9EQ2 LEU A 26  ? UNP Q9FMR9 ? ? 'expression tag'        -3  26  
1 9EQ2 GLU A 27  ? UNP Q9FMR9 ? ? 'expression tag'        -2  27  
1 9EQ2 ASP A 28  ? UNP Q9FMR9 ? ? 'expression tag'        -1  28  
1 9EQ2 PRO A 29  ? UNP Q9FMR9 ? ? 'expression tag'        0   29  
2 9EQ2 MET D 1   ? UNP Q9FJW0 ? ? 'initiating methionine' -17 30  
2 9EQ2 ALA D 2   ? UNP Q9FJW0 ? ? 'expression tag'        -16 31  
2 9EQ2 ASP D 3   ? UNP Q9FJW0 ? ? 'expression tag'        -15 32  
2 9EQ2 LEU D 4   ? UNP Q9FJW0 ? ? 'expression tag'        -14 33  
2 9EQ2 ASN D 5   ? UNP Q9FJW0 ? ? 'expression tag'        -13 34  
2 9EQ2 TRP D 6   ? UNP Q9FJW0 ? ? 'expression tag'        -12 35  
2 9EQ2 ILE D 7   ? UNP Q9FJW0 ? ? 'expression tag'        -11 36  
2 9EQ2 SER D 8   ? UNP Q9FJW0 ? ? 'expression tag'        -10 37  
2 9EQ2 ALA D 9   ? UNP Q9FJW0 ? ? 'expression tag'        -9  38  
2 9EQ2 GLY D 10  ? UNP Q9FJW0 ? ? 'expression tag'        -8  39  
2 9EQ2 HIS D 11  ? UNP Q9FJW0 ? ? 'expression tag'        -7  40  
2 9EQ2 ALA D 12  ? UNP Q9FJW0 ? ? 'expression tag'        -6  41  
2 9EQ2 ILE D 13  ? UNP Q9FJW0 ? ? 'expression tag'        -5  42  
2 9EQ2 ALA D 14  ? UNP Q9FJW0 ? ? 'expression tag'        -4  43  
2 9EQ2 ASP D 15  ? UNP Q9FJW0 ? ? 'expression tag'        -3  44  
2 9EQ2 VAL D 16  ? UNP Q9FJW0 ? ? 'expression tag'        -2  45  
2 9EQ2 GLY D 17  ? UNP Q9FJW0 ? ? 'expression tag'        -1  46  
2 9EQ2 THR D 18  ? UNP Q9FJW0 ? ? 'expression tag'        0   47  
3 9EQ2 MET C 1   ? UNP Q9FMR9 ? ? 'initiating methionine' -28 48  
3 9EQ2 GLY C 2   ? UNP Q9FMR9 ? ? 'expression tag'        -27 49  
3 9EQ2 SER C 3   ? UNP Q9FMR9 ? ? 'expression tag'        -26 50  
3 9EQ2 SER C 4   ? UNP Q9FMR9 ? ? 'expression tag'        -25 51  
3 9EQ2 HIS C 5   ? UNP Q9FMR9 ? ? 'expression tag'        -24 52  
3 9EQ2 HIS C 6   ? UNP Q9FMR9 ? ? 'expression tag'        -23 53  
3 9EQ2 HIS C 7   ? UNP Q9FMR9 ? ? 'expression tag'        -22 54  
3 9EQ2 HIS C 8   ? UNP Q9FMR9 ? ? 'expression tag'        -21 55  
3 9EQ2 HIS C 9   ? UNP Q9FMR9 ? ? 'expression tag'        -20 56  
3 9EQ2 HIS C 10  ? UNP Q9FMR9 ? ? 'expression tag'        -19 57  
3 9EQ2 HIS C 11  ? UNP Q9FMR9 ? ? 'expression tag'        -18 58  
3 9EQ2 HIS C 12  ? UNP Q9FMR9 ? ? 'expression tag'        -17 59  
3 9EQ2 SER C 13  ? UNP Q9FMR9 ? ? 'expression tag'        -16 60  
3 9EQ2 SER C 14  ? UNP Q9FMR9 ? ? 'expression tag'        -15 61  
3 9EQ2 GLY C 15  ? UNP Q9FMR9 ? ? 'expression tag'        -14 62  
3 9EQ2 GLU C 16  ? UNP Q9FMR9 ? ? 'expression tag'        -13 63  
3 9EQ2 ASN C 17  ? UNP Q9FMR9 ? ? 'expression tag'        -12 64  
3 9EQ2 LEU C 18  ? UNP Q9FMR9 ? ? 'expression tag'        -11 65  
3 9EQ2 TYR C 19  ? UNP Q9FMR9 ? ? 'expression tag'        -10 66  
3 9EQ2 PHE C 20  ? UNP Q9FMR9 ? ? 'expression tag'        -9  67  
3 9EQ2 GLN C 21  ? UNP Q9FMR9 ? ? 'expression tag'        -8  68  
3 9EQ2 GLY C 22  ? UNP Q9FMR9 ? ? 'expression tag'        -7  69  
3 9EQ2 SER C 23  ? UNP Q9FMR9 ? ? 'expression tag'        -6  70  
3 9EQ2 HIS C 24  ? UNP Q9FMR9 ? ? 'expression tag'        -5  71  
3 9EQ2 MET C 25  ? UNP Q9FMR9 ? ? 'expression tag'        -4  72  
3 9EQ2 LEU C 26  ? UNP Q9FMR9 ? ? 'expression tag'        -3  73  
3 9EQ2 GLU C 27  ? UNP Q9FMR9 ? ? 'expression tag'        -2  74  
3 9EQ2 ASP C 28  ? UNP Q9FMR9 ? ? 'expression tag'        -1  75  
3 9EQ2 PRO C 29  ? UNP Q9FMR9 ? ? 'expression tag'        0   76  
4 9EQ2 MET B 1   ? UNP Q9FMR9 ? ? 'initiating methionine' -28 77  
4 9EQ2 GLY B 2   ? UNP Q9FMR9 ? ? 'expression tag'        -27 78  
4 9EQ2 SER B 3   ? UNP Q9FMR9 ? ? 'expression tag'        -26 79  
4 9EQ2 SER B 4   ? UNP Q9FMR9 ? ? 'expression tag'        -25 80  
4 9EQ2 HIS B 5   ? UNP Q9FMR9 ? ? 'expression tag'        -24 81  
4 9EQ2 HIS B 6   ? UNP Q9FMR9 ? ? 'expression tag'        -23 82  
4 9EQ2 HIS B 7   ? UNP Q9FMR9 ? ? 'expression tag'        -22 83  
4 9EQ2 HIS B 8   ? UNP Q9FMR9 ? ? 'expression tag'        -21 84  
4 9EQ2 HIS B 9   ? UNP Q9FMR9 ? ? 'expression tag'        -20 85  
4 9EQ2 HIS B 10  ? UNP Q9FMR9 ? ? 'expression tag'        -19 86  
4 9EQ2 HIS B 11  ? UNP Q9FMR9 ? ? 'expression tag'        -18 87  
4 9EQ2 HIS B 12  ? UNP Q9FMR9 ? ? 'expression tag'        -17 88  
4 9EQ2 SER B 13  ? UNP Q9FMR9 ? ? 'expression tag'        -16 89  
4 9EQ2 SER B 14  ? UNP Q9FMR9 ? ? 'expression tag'        -15 90  
4 9EQ2 GLY B 15  ? UNP Q9FMR9 ? ? 'expression tag'        -14 91  
4 9EQ2 GLU B 16  ? UNP Q9FMR9 ? ? 'expression tag'        -13 92  
4 9EQ2 ASN B 17  ? UNP Q9FMR9 ? ? 'expression tag'        -12 93  
4 9EQ2 LEU B 18  ? UNP Q9FMR9 ? ? 'expression tag'        -11 94  
4 9EQ2 TYR B 19  ? UNP Q9FMR9 ? ? 'expression tag'        -10 95  
4 9EQ2 PHE B 20  ? UNP Q9FMR9 ? ? 'expression tag'        -9  96  
4 9EQ2 GLN B 21  ? UNP Q9FMR9 ? ? 'expression tag'        -8  97  
4 9EQ2 GLY B 22  ? UNP Q9FMR9 ? ? 'expression tag'        -7  98  
4 9EQ2 SER B 23  ? UNP Q9FMR9 ? ? 'expression tag'        -6  99  
4 9EQ2 HIS B 24  ? UNP Q9FMR9 ? ? 'expression tag'        -5  100 
4 9EQ2 MET B 25  ? UNP Q9FMR9 ? ? 'expression tag'        -4  101 
4 9EQ2 LEU B 26  ? UNP Q9FMR9 ? ? 'expression tag'        -3  102 
4 9EQ2 GLU B 27  ? UNP Q9FMR9 ? ? 'expression tag'        -2  103 
4 9EQ2 ASP B 28  ? UNP Q9FMR9 ? ? 'expression tag'        -1  104 
4 9EQ2 PRO B 29  ? UNP Q9FMR9 ? ? 'expression tag'        0   105 
5 9EQ2 MET F 1   ? UNP Q9FJW0 ? ? 'initiating methionine' -17 106 
5 9EQ2 ALA F 2   ? UNP Q9FJW0 ? ? 'expression tag'        -16 107 
5 9EQ2 ASP F 3   ? UNP Q9FJW0 ? ? 'expression tag'        -15 108 
5 9EQ2 LEU F 4   ? UNP Q9FJW0 ? ? 'expression tag'        -14 109 
5 9EQ2 ASN F 5   ? UNP Q9FJW0 ? ? 'expression tag'        -13 110 
5 9EQ2 TRP F 6   ? UNP Q9FJW0 ? ? 'expression tag'        -12 111 
5 9EQ2 ILE F 7   ? UNP Q9FJW0 ? ? 'expression tag'        -11 112 
5 9EQ2 SER F 8   ? UNP Q9FJW0 ? ? 'expression tag'        -10 113 
5 9EQ2 ALA F 9   ? UNP Q9FJW0 ? ? 'expression tag'        -9  114 
5 9EQ2 GLY F 10  ? UNP Q9FJW0 ? ? 'expression tag'        -8  115 
5 9EQ2 HIS F 11  ? UNP Q9FJW0 ? ? 'expression tag'        -7  116 
5 9EQ2 ALA F 12  ? UNP Q9FJW0 ? ? 'expression tag'        -6  117 
5 9EQ2 ILE F 13  ? UNP Q9FJW0 ? ? 'expression tag'        -5  118 
5 9EQ2 ALA F 14  ? UNP Q9FJW0 ? ? 'expression tag'        -4  119 
5 9EQ2 ASP F 15  ? UNP Q9FJW0 ? ? 'expression tag'        -3  120 
5 9EQ2 VAL F 16  ? UNP Q9FJW0 ? ? 'expression tag'        -2  121 
5 9EQ2 GLY F 17  ? UNP Q9FJW0 ? ? 'expression tag'        -1  122 
5 9EQ2 THR F 18  ? UNP Q9FJW0 ? ? 'expression tag'        0   123 
6 9EQ2 MET E 1   ? UNP Q9FJW0 ? ? 'initiating methionine' -17 124 
6 9EQ2 ALA E 2   ? UNP Q9FJW0 ? ? 'expression tag'        -16 125 
6 9EQ2 ASP E 3   ? UNP Q9FJW0 ? ? 'expression tag'        -15 126 
6 9EQ2 LEU E 4   ? UNP Q9FJW0 ? ? 'expression tag'        -14 127 
6 9EQ2 ASN E 5   ? UNP Q9FJW0 ? ? 'expression tag'        -13 128 
6 9EQ2 TRP E 6   ? UNP Q9FJW0 ? ? 'expression tag'        -12 129 
6 9EQ2 ILE E 7   ? UNP Q9FJW0 ? ? 'expression tag'        -11 130 
6 9EQ2 SER E 8   ? UNP Q9FJW0 ? ? 'expression tag'        -10 131 
6 9EQ2 ALA E 9   ? UNP Q9FJW0 ? ? 'expression tag'        -9  132 
6 9EQ2 GLY E 10  ? UNP Q9FJW0 ? ? 'expression tag'        -8  133 
6 9EQ2 HIS E 11  ? UNP Q9FJW0 ? ? 'expression tag'        -7  134 
6 9EQ2 ALA E 12  ? UNP Q9FJW0 ? ? 'expression tag'        -6  135 
6 9EQ2 ILE E 13  ? UNP Q9FJW0 ? ? 'expression tag'        -5  136 
6 9EQ2 ALA E 14  ? UNP Q9FJW0 ? ? 'expression tag'        -4  137 
6 9EQ2 ASP E 15  ? UNP Q9FJW0 ? ? 'expression tag'        -3  138 
6 9EQ2 VAL E 16  ? UNP Q9FJW0 ? ? 'expression tag'        -2  139 
6 9EQ2 GLY E 17  ? UNP Q9FJW0 ? ? 'expression tag'        -1  140 
6 9EQ2 THR E 18  ? UNP Q9FJW0 ? ? 'expression tag'        0   141 
7 9EQ2 MET G 1   ? UNP Q5XF05 ? ? 'initiating methionine' -29 142 
7 9EQ2 GLY G 2   ? UNP Q5XF05 ? ? 'expression tag'        -28 143 
7 9EQ2 SER G 3   ? UNP Q5XF05 ? ? 'expression tag'        -27 144 
7 9EQ2 SER G 4   ? UNP Q5XF05 ? ? 'expression tag'        -26 145 
7 9EQ2 HIS G 5   ? UNP Q5XF05 ? ? 'expression tag'        -25 146 
7 9EQ2 HIS G 6   ? UNP Q5XF05 ? ? 'expression tag'        -24 147 
7 9EQ2 HIS G 7   ? UNP Q5XF05 ? ? 'expression tag'        -23 148 
7 9EQ2 HIS G 8   ? UNP Q5XF05 ? ? 'expression tag'        -22 149 
7 9EQ2 HIS G 9   ? UNP Q5XF05 ? ? 'expression tag'        -21 150 
7 9EQ2 HIS G 10  ? UNP Q5XF05 ? ? 'expression tag'        -20 151 
7 9EQ2 HIS G 11  ? UNP Q5XF05 ? ? 'expression tag'        -19 152 
7 9EQ2 HIS G 12  ? UNP Q5XF05 ? ? 'expression tag'        -18 153 
7 9EQ2 HIS G 13  ? UNP Q5XF05 ? ? 'expression tag'        -17 154 
7 9EQ2 HIS G 14  ? UNP Q5XF05 ? ? 'expression tag'        -16 155 
7 9EQ2 MET G 15  ? UNP Q5XF05 ? ? 'expression tag'        -15 156 
7 9EQ2 THR G 16  ? UNP Q5XF05 ? ? 'expression tag'        -14 157 
7 9EQ2 ASP G 17  ? UNP Q5XF05 ? ? 'expression tag'        -13 158 
7 9EQ2 VAL G 18  ? UNP Q5XF05 ? ? 'expression tag'        -12 159 
7 9EQ2 THR G 19  ? UNP Q5XF05 ? ? 'expression tag'        -11 160 
7 9EQ2 ILE G 20  ? UNP Q5XF05 ? ? 'expression tag'        -10 161 
7 9EQ2 LYS G 21  ? UNP Q5XF05 ? ? 'expression tag'        -9  162 
7 9EQ2 GLY G 22  ? UNP Q5XF05 ? ? 'expression tag'        -8  163 
7 9EQ2 GLY G 23  ? UNP Q5XF05 ? ? 'expression tag'        -7  164 
7 9EQ2 GLU G 24  ? UNP Q5XF05 ? ? 'expression tag'        -6  165 
7 9EQ2 ASN G 25  ? UNP Q5XF05 ? ? 'expression tag'        -5  166 
7 9EQ2 LEU G 26  ? UNP Q5XF05 ? ? 'expression tag'        -4  167 
7 9EQ2 TYR G 27  ? UNP Q5XF05 ? ? 'expression tag'        -3  168 
7 9EQ2 PHE G 28  ? UNP Q5XF05 ? ? 'expression tag'        -2  169 
7 9EQ2 GLN G 29  ? UNP Q5XF05 ? ? 'expression tag'        -1  170 
7 9EQ2 GLY G 30  ? UNP Q5XF05 ? ? 'expression tag'        0   171 
7 9EQ2 LEU G 507 ? UNP Q5XF05 ? ? 'expression tag'        477 172 
7 9EQ2 GLU G 508 ? UNP Q5XF05 ? ? 'expression tag'        478 173 
7 9EQ2 VAL G 509 ? UNP Q5XF05 ? ? 'expression tag'        479 174 
7 9EQ2 LEU G 510 ? UNP Q5XF05 ? ? 'expression tag'        480 175 
7 9EQ2 PHE G 511 ? UNP Q5XF05 ? ? 'expression tag'        481 176 
7 9EQ2 GLN G 512 ? UNP Q5XF05 ? ? 'expression tag'        482 177 
7 9EQ2 GLY G 513 ? UNP Q5XF05 ? ? 'expression tag'        483 178 
7 9EQ2 PRO G 514 ? UNP Q5XF05 ? ? 'expression tag'        484 179 
7 9EQ2 TRP G 515 ? UNP Q5XF05 ? ? 'expression tag'        485 180 
7 9EQ2 SER G 516 ? UNP Q5XF05 ? ? 'expression tag'        486 181 
7 9EQ2 HIS G 517 ? UNP Q5XF05 ? ? 'expression tag'        487 182 
7 9EQ2 PRO G 518 ? UNP Q5XF05 ? ? 'expression tag'        488 183 
7 9EQ2 GLN G 519 ? UNP Q5XF05 ? ? 'expression tag'        489 184 
7 9EQ2 PHE G 520 ? UNP Q5XF05 ? ? 'expression tag'        490 185 
7 9EQ2 GLU G 521 ? UNP Q5XF05 ? ? 'expression tag'        491 186 
7 9EQ2 LYS G 522 ? UNP Q5XF05 ? ? 'expression tag'        492 187 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   heptameric 
_pdbx_struct_assembly.oligomeric_count     7 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN A 74  ? GLN A 90  ? GLN A 45  GLN A 61  1 ? 17 
HELX_P HELX_P2  AA2 GLY A 107 ? GLY A 120 ? GLY A 78  GLY A 91  1 ? 14 
HELX_P HELX_P3  AA3 SER A 131 ? SER A 135 ? SER A 102 SER A 106 5 ? 5  
HELX_P HELX_P4  AA4 LYS A 139 ? ALA A 151 ? LYS A 110 ALA A 122 1 ? 13 
HELX_P HELX_P5  AA5 LEU A 272 ? ASN A 279 ? LEU A 243 ASN A 250 1 ? 8  
HELX_P HELX_P6  AA6 LEU A 307 ? GLY A 322 ? LEU A 278 GLY A 293 1 ? 16 
HELX_P HELX_P7  AA7 VAL A 336 ? LEU A 339 ? VAL A 307 LEU A 310 5 ? 4  
HELX_P HELX_P8  AA8 ASP A 340 ? LEU A 351 ? ASP A 311 LEU A 322 1 ? 12 
HELX_P HELX_P9  AA9 PRO A 382 ? ASP A 387 ? PRO A 353 ASP A 358 1 ? 6  
HELX_P HELX_P10 AB1 ASP A 398 ? GLU A 413 ? ASP A 369 GLU A 384 1 ? 16 
HELX_P HELX_P11 AB2 ASP A 418 ? THR A 432 ? ASP A 389 THR A 403 1 ? 15 
HELX_P HELX_P12 AB3 SER A 433 ? LEU A 440 ? SER A 404 LEU A 411 1 ? 8  
HELX_P HELX_P13 AB4 LEU A 440 ? ASN A 451 ? LEU A 411 ASN A 422 1 ? 12 
HELX_P HELX_P14 AB5 CYS A 457 ? TYR A 468 ? CYS A 428 TYR A 439 1 ? 12 
HELX_P HELX_P15 AB6 ASP A 470 ? GLU A 480 ? ASP A 441 GLU A 451 1 ? 11 
HELX_P HELX_P16 AB7 VAL B 64  ? GLU B 79  ? VAL D 46  GLU D 61  1 ? 16 
HELX_P HELX_P17 AB8 GLY B 96  ? GLY B 109 ? GLY D 78  GLY D 91  1 ? 14 
HELX_P HELX_P18 AB9 SER B 120 ? LEU B 125 ? SER D 102 LEU D 107 5 ? 6  
HELX_P HELX_P19 AC1 SER B 128 ? ALA B 140 ? SER D 110 ALA D 122 1 ? 13 
HELX_P HELX_P20 AC2 LEU B 259 ? ASN B 266 ? LEU D 241 ASN D 248 1 ? 8  
HELX_P HELX_P21 AC3 SER B 285 ? GLU B 301 ? SER D 267 GLU D 283 1 ? 17 
HELX_P HELX_P22 AC4 GLU B 315 ? LEU B 319 ? GLU D 297 LEU D 301 5 ? 5  
HELX_P HELX_P23 AC5 ASP B 320 ? ASN B 333 ? ASP D 302 ASN D 315 1 ? 14 
HELX_P HELX_P24 AC6 PRO B 358 ? ILE B 361 ? PRO D 340 ILE D 343 5 ? 4  
HELX_P HELX_P25 AC7 PRO B 362 ? ASP B 367 ? PRO D 344 ASP D 349 1 ? 6  
HELX_P HELX_P26 AC8 THR B 378 ? GLU B 393 ? THR D 360 GLU D 375 1 ? 16 
HELX_P HELX_P27 AC9 ASN B 398 ? THR B 412 ? ASN D 380 THR D 394 1 ? 15 
HELX_P HELX_P28 AD1 SER B 413 ? ARG B 431 ? SER D 395 ARG D 413 1 ? 19 
HELX_P HELX_P29 AD2 GLU B 437 ? LEU B 447 ? GLU D 419 LEU D 429 1 ? 11 
HELX_P HELX_P30 AD3 ASP B 450 ? MET B 466 ? ASP D 432 MET D 448 1 ? 17 
HELX_P HELX_P31 AD4 GLN C 74  ? GLN C 90  ? GLN C 45  GLN C 61  1 ? 17 
HELX_P HELX_P32 AD5 GLY C 107 ? GLY C 120 ? GLY C 78  GLY C 91  1 ? 14 
HELX_P HELX_P33 AD6 GLY C 130 ? TYR C 134 ? GLY C 101 TYR C 105 1 ? 5  
HELX_P HELX_P34 AD7 LYS C 139 ? ALA C 151 ? LYS C 110 ALA C 122 1 ? 13 
HELX_P HELX_P35 AD8 LEU C 272 ? ALA C 280 ? LEU C 243 ALA C 251 1 ? 9  
HELX_P HELX_P36 AD9 LEU C 307 ? GLU C 321 ? LEU C 278 GLU C 292 1 ? 15 
HELX_P HELX_P37 AE1 GLU C 335 ? LEU C 339 ? GLU C 306 LEU C 310 5 ? 5  
HELX_P HELX_P38 AE2 ASP C 340 ? LEU C 351 ? ASP C 311 LEU C 322 1 ? 12 
HELX_P HELX_P39 AE3 PRO C 382 ? ASP C 387 ? PRO C 353 ASP C 358 1 ? 6  
HELX_P HELX_P40 AE4 ASP C 398 ? GLU C 413 ? ASP C 369 GLU C 384 1 ? 16 
HELX_P HELX_P41 AE5 ASP C 418 ? THR C 432 ? ASP C 389 THR C 403 1 ? 15 
HELX_P HELX_P42 AE6 LEU C 440 ? ASN C 451 ? LEU C 411 ASN C 422 1 ? 12 
HELX_P HELX_P43 AE7 CYS C 457 ? TYR C 468 ? CYS C 428 TYR C 439 1 ? 12 
HELX_P HELX_P44 AE8 ASP C 470 ? GLN C 481 ? ASP C 441 GLN C 452 1 ? 12 
HELX_P HELX_P45 AE9 ILE D 47  ? THR D 51  ? ILE B 18  THR B 22  5 ? 5  
HELX_P HELX_P46 AF1 GLN D 74  ? GLN D 90  ? GLN B 45  GLN B 61  1 ? 17 
HELX_P HELX_P47 AF2 LYS D 91  ? ALA D 94  ? LYS B 62  ALA B 65  5 ? 4  
HELX_P HELX_P48 AF3 GLY D 107 ? GLY D 120 ? GLY B 78  GLY B 91  1 ? 14 
HELX_P HELX_P49 AF4 SER D 131 ? VAL D 133 ? SER B 102 VAL B 104 5 ? 3  
HELX_P HELX_P50 AF5 LYS D 139 ? ALA D 151 ? LYS B 110 ALA B 122 1 ? 13 
HELX_P HELX_P51 AF6 LEU D 272 ? ASN D 279 ? LEU B 243 ASN B 250 1 ? 8  
HELX_P HELX_P52 AF7 LEU D 307 ? GLU D 321 ? LEU B 278 GLU B 292 1 ? 15 
HELX_P HELX_P53 AF8 GLU D 335 ? LEU D 339 ? GLU B 306 LEU B 310 5 ? 5  
HELX_P HELX_P54 AF9 ASP D 340 ? LEU D 351 ? ASP B 311 LEU B 322 1 ? 12 
HELX_P HELX_P55 AG1 PRO D 382 ? ASP D 387 ? PRO B 353 ASP B 358 1 ? 6  
HELX_P HELX_P56 AG2 ASP D 398 ? GLU D 413 ? ASP B 369 GLU B 384 1 ? 16 
HELX_P HELX_P57 AG3 ASP D 418 ? THR D 432 ? ASP B 389 THR B 403 1 ? 15 
HELX_P HELX_P58 AG4 SER D 433 ? LEU D 440 ? SER B 404 LEU B 411 1 ? 8  
HELX_P HELX_P59 AG5 LEU D 440 ? MET D 450 ? LEU B 411 MET B 421 1 ? 11 
HELX_P HELX_P60 AG6 CYS D 457 ? LEU D 467 ? CYS B 428 LEU B 438 1 ? 11 
HELX_P HELX_P61 AG7 ASP D 470 ? GLN D 481 ? ASP B 441 GLN B 452 1 ? 12 
HELX_P HELX_P62 AG8 VAL E 64  ? GLU E 79  ? VAL F 46  GLU F 61  1 ? 16 
HELX_P HELX_P63 AG9 GLY E 96  ? GLY E 109 ? GLY F 78  GLY F 91  1 ? 14 
HELX_P HELX_P64 AH1 SER E 128 ? ALA E 140 ? SER F 110 ALA F 122 1 ? 13 
HELX_P HELX_P65 AH2 LEU E 259 ? SER E 267 ? LEU F 241 SER F 249 1 ? 9  
HELX_P HELX_P66 AH3 SER E 285 ? TRP E 298 ? SER F 267 TRP F 280 1 ? 14 
HELX_P HELX_P67 AH4 GLU E 315 ? LEU E 319 ? GLU F 297 LEU F 301 5 ? 5  
HELX_P HELX_P68 AH5 ASP E 320 ? GLU E 332 ? ASP F 302 GLU F 314 1 ? 13 
HELX_P HELX_P69 AH6 PRO E 362 ? ASP E 367 ? PRO F 344 ASP F 349 1 ? 6  
HELX_P HELX_P70 AH7 THR E 378 ? GLU E 393 ? THR F 360 GLU F 375 1 ? 16 
HELX_P HELX_P71 AH8 ASN E 398 ? THR E 412 ? ASN F 380 THR F 394 1 ? 15 
HELX_P HELX_P72 AH9 SER E 413 ? ARG E 431 ? SER F 395 ARG F 413 1 ? 19 
HELX_P HELX_P73 AI1 GLU E 437 ? PHE E 448 ? GLU F 419 PHE F 430 1 ? 12 
HELX_P HELX_P74 AI2 ASP E 450 ? MET E 466 ? ASP F 432 MET F 448 1 ? 17 
HELX_P HELX_P75 AI3 VAL F 64  ? GLU F 79  ? VAL E 46  GLU E 61  1 ? 16 
HELX_P HELX_P76 AI4 GLY F 96  ? GLY F 109 ? GLY E 78  GLY E 91  1 ? 14 
HELX_P HELX_P77 AI5 SER F 128 ? ALA F 140 ? SER E 110 ALA E 122 1 ? 13 
HELX_P HELX_P78 AI6 LEU F 259 ? SER F 267 ? LEU E 241 SER E 249 1 ? 9  
HELX_P HELX_P79 AI7 SER F 285 ? GLY F 302 ? SER E 267 GLY E 284 1 ? 18 
HELX_P HELX_P80 AI8 GLU F 315 ? LEU F 319 ? GLU E 297 LEU E 301 5 ? 5  
HELX_P HELX_P81 AI9 ASP F 320 ? GLU F 332 ? ASP E 302 GLU E 314 1 ? 13 
HELX_P HELX_P82 AJ1 PRO F 362 ? ASP F 367 ? PRO E 344 ASP E 349 1 ? 6  
HELX_P HELX_P83 AJ2 THR F 378 ? ASP F 394 ? THR E 360 ASP E 376 1 ? 17 
HELX_P HELX_P84 AJ3 ASN F 398 ? THR F 412 ? ASN E 380 THR E 394 1 ? 15 
HELX_P HELX_P85 AJ4 SER F 413 ? ARG F 431 ? SER E 395 ARG E 413 1 ? 19 
HELX_P HELX_P86 AJ5 GLU F 437 ? LEU F 447 ? GLU E 419 LEU E 429 1 ? 11 
HELX_P HELX_P87 AJ6 ASP F 450 ? TYR F 465 ? ASP E 432 TYR E 447 1 ? 16 
HELX_P HELX_P88 AJ7 SER G 385 ? PHE G 396 ? SER G 355 PHE G 366 1 ? 12 
HELX_P HELX_P89 AJ8 SER G 400 ? GLN G 405 ? SER G 370 GLN G 375 1 ? 6  
HELX_P HELX_P90 AJ9 LEU G 406 ? THR G 410 ? LEU G 376 THR G 380 5 ? 5  
HELX_P HELX_P91 AK1 THR G 411 ? SER G 413 ? THR G 381 SER G 383 5 ? 3  
HELX_P HELX_P92 AK2 SER G 414 ? PHE G 419 ? SER G 384 PHE G 389 1 ? 6  
HELX_P HELX_P93 AK3 THR G 424 ? PHE G 438 ? THR G 394 PHE G 408 1 ? 15 
HELX_P HELX_P94 AK4 ASP G 442 ? LYS G 455 ? ASP G 412 LYS G 425 1 ? 14 
HELX_P HELX_P95 AK5 ARG G 458 ? CYS G 465 ? ARG G 428 CYS G 435 1 ? 8  
HELX_P HELX_P96 AK6 THR G 467 ? VAL G 481 ? THR G 437 VAL G 451 1 ? 15 
HELX_P HELX_P97 AK7 PRO G 488 ? LEU G 504 ? PRO G 458 LEU G 474 1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 6 ? 
AA6 ? 3 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 5 ? 
AB1 ? 3 ? 
AB2 ? 2 ? 
AB3 ? 2 ? 
AB4 ? 6 ? 
AB5 ? 3 ? 
AB6 ? 2 ? 
AB7 ? 5 ? 
AB8 ? 3 ? 
AB9 ? 2 ? 
AC1 ? 5 ? 
AC2 ? 3 ? 
AC3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? parallel      
AA5 3 4 ? parallel      
AA5 4 5 ? parallel      
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? parallel      
AA9 3 4 ? parallel      
AA9 4 5 ? parallel      
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? parallel      
AB4 3 4 ? parallel      
AB4 4 5 ? parallel      
AB4 5 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? parallel      
AB7 3 4 ? parallel      
AB7 4 5 ? parallel      
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AC1 1 2 ? parallel      
AC1 2 3 ? parallel      
AC1 3 4 ? parallel      
AC1 4 5 ? parallel      
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 67  ? ALA A 68  ? LEU A 38  ALA A 39  
AA1 2 PHE A 71  ? VAL A 72  ? PHE A 42  VAL A 43  
AA2 1 PHE A 125 ? VAL A 129 ? PHE A 96  VAL A 100 
AA2 2 VAL A 330 ? ASP A 334 ? VAL A 301 ASP A 305 
AA2 3 ILE A 358 ? THR A 363 ? ILE A 329 THR A 334 
AA2 4 ALA A 97  ? ALA A 101 ? ALA A 68  ALA A 72  
AA2 5 LEU A 389 ? ARG A 393 ? LEU A 360 ARG A 364 
AA2 6 PHE B 448 ? LEU B 449 ? PHE D 430 LEU D 431 
AA3 1 GLN A 268 ? THR A 271 ? GLN A 239 THR A 242 
AA3 2 ILE A 152 ? ILE A 156 ? ILE A 123 ILE A 127 
AA3 3 ALA A 324 ? PRO A 328 ? ALA A 295 PRO A 299 
AA4 1 VAL A 367 ? ASN A 369 ? VAL A 338 ASN A 340 
AA4 2 PRO A 376 ? PRO A 378 ? PRO A 347 PRO A 349 
AA5 1 PHE B 114 ? ALA B 118 ? PHE D 96  ALA D 100 
AA5 2 VAL B 310 ? ASP B 314 ? VAL D 292 ASP D 296 
AA5 3 ILE B 338 ? THR B 343 ? ILE D 320 THR D 325 
AA5 4 ALA B 86  ? GLY B 91  ? ALA D 68  GLY D 73  
AA5 5 LEU B 369 ? THR B 374 ? LEU D 351 THR D 356 
AA5 6 TYR D 468 ? LEU D 469 ? TYR B 439 LEU B 440 
AA6 1 VAL B 257 ? THR B 258 ? VAL D 239 THR D 240 
AA6 2 ILE B 141 ? ARG B 144 ? ILE D 123 ARG D 126 
AA6 3 GLU B 305 ? PRO B 308 ? GLU D 287 PRO D 290 
AA7 1 THR B 348 ? THR B 349 ? THR D 330 THR D 331 
AA7 2 LYS B 356 ? SER B 357 ? LYS D 338 SER D 339 
AA8 1 LEU C 67  ? ALA C 68  ? LEU C 38  ALA C 39  
AA8 2 PHE C 71  ? VAL C 72  ? PHE C 42  VAL C 43  
AA9 1 PHE C 125 ? VAL C 129 ? PHE C 96  VAL C 100 
AA9 2 VAL C 330 ? ASP C 334 ? VAL C 301 ASP C 305 
AA9 3 ILE C 358 ? THR C 363 ? ILE C 329 THR C 334 
AA9 4 ALA C 97  ? ALA C 101 ? ALA C 68  ALA C 72  
AA9 5 LEU C 389 ? ARG C 393 ? LEU C 360 ARG C 364 
AB1 1 GLN C 268 ? THR C 271 ? GLN C 239 THR C 242 
AB1 2 ILE C 152 ? ILE C 156 ? ILE C 123 ILE C 127 
AB1 3 ALA C 324 ? PRO C 328 ? ALA C 295 PRO C 299 
AB2 1 VAL C 367 ? ASN C 369 ? VAL C 338 ASN C 340 
AB2 2 PRO C 376 ? PRO C 378 ? PRO C 347 PRO C 349 
AB3 1 LEU D 67  ? ALA D 68  ? LEU B 38  ALA B 39  
AB3 2 PHE D 71  ? VAL D 72  ? PHE B 42  VAL B 43  
AB4 1 MET D 128 ? VAL D 129 ? MET B 99  VAL B 100 
AB4 2 VAL D 330 ? ASP D 334 ? VAL B 301 ASP B 305 
AB4 3 ILE D 358 ? THR D 363 ? ILE B 329 THR B 334 
AB4 4 ALA D 97  ? ALA D 101 ? ALA B 68  ALA B 72  
AB4 5 LEU D 389 ? ARG D 393 ? LEU B 360 ARG B 364 
AB4 6 PHE F 448 ? LEU F 449 ? PHE E 430 LEU E 431 
AB5 1 GLN D 268 ? THR D 271 ? GLN B 239 THR B 242 
AB5 2 ILE D 152 ? ILE D 156 ? ILE B 123 ILE B 127 
AB5 3 ALA D 324 ? PRO D 328 ? ALA B 295 PRO B 299 
AB6 1 VAL D 367 ? ASN D 369 ? VAL B 338 ASN B 340 
AB6 2 PRO D 376 ? PRO D 378 ? PRO B 347 PRO B 349 
AB7 1 PHE E 114 ? MET E 116 ? PHE F 96  MET F 98  
AB7 2 VAL E 310 ? ILE E 313 ? VAL F 292 ILE F 295 
AB7 3 VAL E 340 ? ALA E 342 ? VAL F 322 ALA F 324 
AB7 4 ALA E 86  ? ALA E 90  ? ALA F 68  ALA F 72  
AB7 5 LEU E 369 ? THR E 373 ? LEU F 351 THR F 355 
AB8 1 VAL E 257 ? THR E 258 ? VAL F 239 THR F 240 
AB8 2 ILE E 141 ? ARG E 144 ? ILE F 123 ARG F 126 
AB8 3 GLU E 305 ? PRO E 308 ? GLU F 287 PRO F 290 
AB9 1 VAL E 347 ? THR E 349 ? VAL F 329 THR F 331 
AB9 2 LYS E 356 ? PRO E 358 ? LYS F 338 PRO F 340 
AC1 1 PHE F 114 ? ILE F 117 ? PHE E 96  ILE E 99  
AC1 2 VAL F 310 ? ILE F 313 ? VAL E 292 ILE E 295 
AC1 3 ILE F 338 ? ALA F 342 ? ILE E 320 ALA E 324 
AC1 4 ALA F 86  ? ILE F 89  ? ALA E 68  ILE E 71  
AC1 5 LEU F 369 ? ILE F 372 ? LEU E 351 ILE E 354 
AC2 1 VAL F 257 ? THR F 258 ? VAL E 239 THR E 240 
AC2 2 ILE F 141 ? ARG F 144 ? ILE E 123 ARG E 126 
AC2 3 GLU F 305 ? PRO F 308 ? GLU E 287 PRO E 290 
AC3 1 VAL F 347 ? THR F 349 ? VAL E 329 THR E 331 
AC3 2 LYS F 356 ? PRO F 358 ? LYS E 338 PRO E 340 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ALA A 68  ? N ALA A 39  O PHE A 71  ? O PHE A 42  
AA2 1 2 N MET A 128 ? N MET A 99  O ASP A 334 ? O ASP A 305 
AA2 2 3 N ILE A 333 ? N ILE A 304 O ILE A 360 ? O ILE A 331 
AA2 3 4 O PHE A 361 ? O PHE A 332 N LEU A 98  ? N LEU A 69  
AA2 4 5 N LEU A 99  ? N LEU A 70  O VAL A 390 ? O VAL A 361 
AA2 5 6 N ILE A 391 ? N ILE A 362 O LEU B 449 ? O LEU D 431 
AA3 1 2 O GLN A 268 ? O GLN A 239 N ILE A 156 ? N ILE A 127 
AA3 2 3 N ARG A 155 ? N ARG A 126 O GLU A 325 ? O GLU A 296 
AA4 1 2 N CYS A 368 ? N CYS A 339 O SER A 377 ? O SER A 348 
AA5 1 2 N ALA B 115 ? N ALA D 97  O PHE B 312 ? O PHE D 294 
AA5 2 3 N LEU B 311 ? N LEU D 293 O ILE B 338 ? O ILE D 320 
AA5 3 4 O THR B 343 ? O THR D 325 N ILE B 89  ? N ILE D 71  
AA5 4 5 N LEU B 88  ? N LEU D 70  O ILE B 372 ? O ILE D 354 
AA5 5 6 N ILE B 371 ? N ILE D 353 O LEU D 469 ? O LEU B 440 
AA6 1 2 O VAL B 257 ? O VAL D 239 N VAL B 143 ? N VAL D 125 
AA6 2 3 N GLY B 142 ? N GLY D 124 O VAL B 307 ? O VAL D 289 
AA7 1 2 N THR B 348 ? N THR D 330 O SER B 357 ? O SER D 339 
AA8 1 2 N ALA C 68  ? N ALA C 39  O PHE C 71  ? O PHE C 42  
AA9 1 2 N MET C 128 ? N MET C 99  O ASP C 334 ? O ASP C 305 
AA9 2 3 N ILE C 333 ? N ILE C 304 O ILE C 360 ? O ILE C 331 
AA9 3 4 O PHE C 361 ? O PHE C 332 N LEU C 98  ? N LEU C 69  
AA9 4 5 N ALA C 97  ? N ALA C 68  O VAL C 390 ? O VAL C 361 
AB1 1 2 O GLN C 268 ? O GLN C 239 N ILE C 156 ? N ILE C 127 
AB1 2 3 N GLY C 153 ? N GLY C 124 O VAL C 327 ? O VAL C 298 
AB2 1 2 N CYS C 368 ? N CYS C 339 O SER C 377 ? O SER C 348 
AB3 1 2 N ALA D 68  ? N ALA B 39  O PHE D 71  ? O PHE B 42  
AB4 1 2 N MET D 128 ? N MET B 99  O ASP D 334 ? O ASP B 305 
AB4 2 3 N LEU D 331 ? N LEU B 302 O ILE D 360 ? O ILE B 331 
AB4 3 4 O PHE D 361 ? O PHE B 332 N LEU D 100 ? N LEU B 71  
AB4 4 5 N ALA D 97  ? N ALA B 68  O VAL D 390 ? O VAL B 361 
AB4 5 6 N ILE D 391 ? N ILE B 362 O LEU F 449 ? O LEU E 431 
AB5 1 2 O GLN D 268 ? O GLN B 239 N ILE D 156 ? N ILE B 127 
AB5 2 3 N ARG D 155 ? N ARG B 126 O GLU D 325 ? O GLU B 296 
AB6 1 2 N CYS D 368 ? N CYS B 339 O SER D 377 ? O SER B 348 
AB7 1 2 N ALA E 115 ? N ALA F 97  O PHE E 312 ? O PHE F 294 
AB7 2 3 N ILE E 313 ? N ILE F 295 O VAL E 340 ? O VAL F 322 
AB7 3 4 O VAL E 341 ? O VAL F 323 N ILE E 87  ? N ILE F 69  
AB7 4 5 N LEU E 88  ? N LEU F 70  O ILE E 372 ? O ILE F 354 
AB8 1 2 O VAL E 257 ? O VAL F 239 N VAL E 143 ? N VAL F 125 
AB8 2 3 N GLY E 142 ? N GLY F 124 O VAL E 307 ? O VAL F 289 
AB9 1 2 N THR E 348 ? N THR F 330 O SER E 357 ? O SER F 339 
AC1 1 2 N ALA F 115 ? N ALA E 97  O VAL F 310 ? O VAL E 292 
AC1 2 3 N LEU F 311 ? N LEU E 293 O VAL F 340 ? O VAL E 322 
AC1 3 4 O VAL F 341 ? O VAL E 323 N ILE F 87  ? N ILE E 69  
AC1 4 5 N LEU F 88  ? N LEU E 70  O ILE F 372 ? O ILE E 354 
AC2 1 2 O VAL F 257 ? O VAL E 239 N VAL F 143 ? N VAL E 125 
AC2 2 3 N GLY F 142 ? N GLY E 124 O VAL F 307 ? O VAL E 289 
AC3 1 2 N THR F 348 ? N THR E 330 O SER F 357 ? O SER E 339 
# 
_pdbx_entry_details.entry_id                   9EQ2 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 359 ? ? -142.64 20.51   
2  1 ALA D 65  ? ? 59.98   -130.15 
3  1 LEU D 107 ? ? 76.24   -2.65   
4  1 SER D 395 ? ? 65.52   160.55  
5  1 THR C 403 ? ? -119.11 -79.87  
6  1 THR F 77  ? ? -93.45  48.42   
7  1 ALA F 122 ? ? -99.13  36.51   
8  1 GLU F 279 ? ? -92.23  -62.71  
9  1 THR F 394 ? ? -99.43  -65.29  
10 1 VAL E 46  ? ? -127.00 -58.46  
11 1 GLU E 264 ? ? -90.00  50.67   
12 1 ARG E 266 ? ? -162.28 105.79  
13 1 ASN G 391 ? ? 81.08   -1.78   
14 1 VAL G 451 ? ? -97.64  -60.77  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9EQ2 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'BACKBONE TRACE' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   AlphaFold 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    9EQ2 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               185042 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'AtR2T complex' 
_em_entity_assembly.details              'AtRuvBL1-AtRuvBL2a in complex with AtRPAP3' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        9EQ2 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R0.6/1' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9EQ2 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              90 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9EQ2 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9EQ2 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 A MET -28 ? A MET 1   
2    1 Y 1 A GLY -27 ? A GLY 2   
3    1 Y 1 A SER -26 ? A SER 3   
4    1 Y 1 A SER -25 ? A SER 4   
5    1 Y 1 A HIS -24 ? A HIS 5   
6    1 Y 1 A HIS -23 ? A HIS 6   
7    1 Y 1 A HIS -22 ? A HIS 7   
8    1 Y 1 A HIS -21 ? A HIS 8   
9    1 Y 1 A HIS -20 ? A HIS 9   
10   1 Y 1 A HIS -19 ? A HIS 10  
11   1 Y 1 A HIS -18 ? A HIS 11  
12   1 Y 1 A HIS -17 ? A HIS 12  
13   1 Y 1 A SER -16 ? A SER 13  
14   1 Y 1 A SER -15 ? A SER 14  
15   1 Y 1 A GLY -14 ? A GLY 15  
16   1 Y 1 A GLU -13 ? A GLU 16  
17   1 Y 1 A ASN -12 ? A ASN 17  
18   1 Y 1 A LEU -11 ? A LEU 18  
19   1 Y 1 A TYR -10 ? A TYR 19  
20   1 Y 1 A PHE -9  ? A PHE 20  
21   1 Y 1 A GLN -8  ? A GLN 21  
22   1 Y 1 A GLY -7  ? A GLY 22  
23   1 Y 1 A SER -6  ? A SER 23  
24   1 Y 1 A HIS -5  ? A HIS 24  
25   1 Y 1 A MET -4  ? A MET 25  
26   1 Y 1 A LEU -3  ? A LEU 26  
27   1 Y 1 A GLU -2  ? A GLU 27  
28   1 Y 1 A ASP -1  ? A ASP 28  
29   1 Y 1 A PRO 0   ? A PRO 29  
30   1 Y 1 A MET 1   ? A MET 30  
31   1 Y 1 A GLU 2   ? A GLU 31  
32   1 Y 1 A LYS 3   ? A LYS 32  
33   1 Y 1 A VAL 4   ? A VAL 33  
34   1 Y 1 A LYS 5   ? A LYS 34  
35   1 Y 1 A ILE 6   ? A ILE 35  
36   1 Y 1 A GLU 7   ? A GLU 36  
37   1 Y 1 A GLU 8   ? A GLU 37  
38   1 Y 1 A ILE 9   ? A ILE 38  
39   1 Y 1 A GLN 10  ? A GLN 39  
40   1 Y 1 A SER 11  ? A SER 40  
41   1 Y 1 A THR 12  ? A THR 41  
42   1 Y 1 A ALA 13  ? A ALA 42  
43   1 Y 1 A LYS 14  ? A LYS 43  
44   1 Y 1 A LYS 15  ? A LYS 44  
45   1 Y 1 A GLN 16  ? A GLN 45  
46   1 Y 1 A ARG 17  ? A ARG 46  
47   1 Y 1 A GLU 129 ? A GLU 158 
48   1 Y 1 A THR 130 ? A THR 159 
49   1 Y 1 A LYS 131 ? A LYS 160 
50   1 Y 1 A GLU 132 ? A GLU 161 
51   1 Y 1 A VAL 133 ? A VAL 162 
52   1 Y 1 A TYR 134 ? A TYR 163 
53   1 Y 1 A GLU 135 ? A GLU 164 
54   1 Y 1 A GLY 136 ? A GLY 165 
55   1 Y 1 A GLU 137 ? A GLU 166 
56   1 Y 1 A VAL 138 ? A VAL 167 
57   1 Y 1 A THR 139 ? A THR 168 
58   1 Y 1 A GLU 140 ? A GLU 169 
59   1 Y 1 A LEU 141 ? A LEU 170 
60   1 Y 1 A SER 142 ? A SER 171 
61   1 Y 1 A PRO 143 ? A PRO 172 
62   1 Y 1 A GLU 144 ? A GLU 173 
63   1 Y 1 A GLU 145 ? A GLU 174 
64   1 Y 1 A THR 146 ? A THR 175 
65   1 Y 1 A GLU 147 ? A GLU 176 
66   1 Y 1 A SER 148 ? A SER 177 
67   1 Y 1 A LEU 149 ? A LEU 178 
68   1 Y 1 A THR 150 ? A THR 179 
69   1 Y 1 A GLY 151 ? A GLY 180 
70   1 Y 1 A GLY 152 ? A GLY 181 
71   1 Y 1 A TYR 153 ? A TYR 182 
72   1 Y 1 A GLY 154 ? A GLY 183 
73   1 Y 1 A LYS 155 ? A LYS 184 
74   1 Y 1 A SER 156 ? A SER 185 
75   1 Y 1 A ILE 157 ? A ILE 186 
76   1 Y 1 A SER 158 ? A SER 187 
77   1 Y 1 A HIS 159 ? A HIS 188 
78   1 Y 1 A VAL 160 ? A VAL 189 
79   1 Y 1 A VAL 161 ? A VAL 190 
80   1 Y 1 A ILE 162 ? A ILE 191 
81   1 Y 1 A THR 163 ? A THR 192 
82   1 Y 1 A LEU 164 ? A LEU 193 
83   1 Y 1 A LYS 165 ? A LYS 194 
84   1 Y 1 A THR 166 ? A THR 195 
85   1 Y 1 A VAL 167 ? A VAL 196 
86   1 Y 1 A LYS 168 ? A LYS 197 
87   1 Y 1 A GLY 169 ? A GLY 198 
88   1 Y 1 A THR 170 ? A THR 199 
89   1 Y 1 A LYS 171 ? A LYS 200 
90   1 Y 1 A HIS 172 ? A HIS 201 
91   1 Y 1 A LEU 173 ? A LEU 202 
92   1 Y 1 A LYS 174 ? A LYS 203 
93   1 Y 1 A LEU 175 ? A LEU 204 
94   1 Y 1 A ASP 176 ? A ASP 205 
95   1 Y 1 A PRO 177 ? A PRO 206 
96   1 Y 1 A THR 178 ? A THR 207 
97   1 Y 1 A ILE 179 ? A ILE 208 
98   1 Y 1 A TYR 180 ? A TYR 209 
99   1 Y 1 A ASP 181 ? A ASP 210 
100  1 Y 1 A ALA 182 ? A ALA 211 
101  1 Y 1 A LEU 183 ? A LEU 212 
102  1 Y 1 A ILE 184 ? A ILE 213 
103  1 Y 1 A LYS 185 ? A LYS 214 
104  1 Y 1 A GLU 186 ? A GLU 215 
105  1 Y 1 A LYS 187 ? A LYS 216 
106  1 Y 1 A VAL 188 ? A VAL 217 
107  1 Y 1 A ALA 189 ? A ALA 218 
108  1 Y 1 A VAL 190 ? A VAL 219 
109  1 Y 1 A GLY 191 ? A GLY 220 
110  1 Y 1 A ASP 192 ? A ASP 221 
111  1 Y 1 A VAL 193 ? A VAL 222 
112  1 Y 1 A ILE 194 ? A ILE 223 
113  1 Y 1 A TYR 195 ? A TYR 224 
114  1 Y 1 A ILE 196 ? A ILE 225 
115  1 Y 1 A GLU 197 ? A GLU 226 
116  1 Y 1 A ALA 198 ? A ALA 227 
117  1 Y 1 A ASN 199 ? A ASN 228 
118  1 Y 1 A SER 200 ? A SER 229 
119  1 Y 1 A GLY 201 ? A GLY 230 
120  1 Y 1 A ALA 202 ? A ALA 231 
121  1 Y 1 A VAL 203 ? A VAL 232 
122  1 Y 1 A LYS 204 ? A LYS 233 
123  1 Y 1 A ARG 205 ? A ARG 234 
124  1 Y 1 A VAL 206 ? A VAL 235 
125  1 Y 1 A GLY 207 ? A GLY 236 
126  1 Y 1 A ARG 208 ? A ARG 237 
127  1 Y 1 A SER 209 ? A SER 238 
128  1 Y 1 A ASP 210 ? A ASP 239 
129  1 Y 1 A ALA 211 ? A ALA 240 
130  1 Y 1 A PHE 212 ? A PHE 241 
131  1 Y 1 A ALA 213 ? A ALA 242 
132  1 Y 1 A THR 214 ? A THR 243 
133  1 Y 1 A GLU 215 ? A GLU 244 
134  1 Y 1 A PHE 216 ? A PHE 245 
135  1 Y 1 A ASP 217 ? A ASP 246 
136  1 Y 1 A LEU 218 ? A LEU 247 
137  1 Y 1 A GLU 219 ? A GLU 248 
138  1 Y 1 A ALA 220 ? A ALA 249 
139  1 Y 1 A GLU 221 ? A GLU 250 
140  1 Y 1 A GLU 222 ? A GLU 251 
141  1 Y 1 A TYR 223 ? A TYR 252 
142  1 Y 1 A VAL 224 ? A VAL 253 
143  1 Y 1 A PRO 225 ? A PRO 254 
144  1 Y 1 A LEU 226 ? A LEU 255 
145  1 Y 1 A PRO 227 ? A PRO 256 
146  1 Y 1 A LYS 228 ? A LYS 257 
147  1 Y 1 A GLY 229 ? A GLY 258 
148  1 Y 1 A GLU 230 ? A GLU 259 
149  1 Y 1 A VAL 231 ? A VAL 260 
150  1 Y 1 A HIS 232 ? A HIS 261 
151  1 Y 1 A LYS 233 ? A LYS 262 
152  1 Y 1 A LYS 234 ? A LYS 263 
153  1 Y 1 A LYS 235 ? A LYS 264 
154  1 Y 1 A GLU 236 ? A GLU 265 
155  1 Y 1 A ILE 237 ? A ILE 266 
156  1 Y 1 A ARG 252 ? A ARG 281 
157  1 Y 1 A PRO 253 ? A PRO 282 
158  1 Y 1 A GLN 254 ? A GLN 283 
159  1 Y 1 A GLY 255 ? A GLY 284 
160  1 Y 1 A GLY 256 ? A GLY 285 
161  1 Y 1 A GLN 257 ? A GLN 286 
162  1 Y 1 A ASP 258 ? A ASP 287 
163  1 Y 1 A ILE 259 ? A ILE 288 
164  1 Y 1 A LEU 260 ? A LEU 289 
165  1 Y 1 A SER 261 ? A SER 290 
166  1 Y 1 A LEU 262 ? A LEU 291 
167  1 Y 1 A MET 263 ? A MET 292 
168  1 Y 1 A GLY 264 ? A GLY 293 
169  1 Y 1 A GLN 265 ? A GLN 294 
170  1 Y 1 A MET 266 ? A MET 295 
171  1 Y 1 A MET 267 ? A MET 296 
172  1 Y 1 A LYS 268 ? A LYS 297 
173  1 Y 1 A PRO 269 ? A PRO 298 
174  1 Y 1 A ARG 270 ? A ARG 299 
175  1 Y 1 A LYS 271 ? A LYS 300 
176  1 Y 1 A THR 272 ? A THR 301 
177  1 Y 1 A GLU 273 ? A GLU 302 
178  1 Y 1 A ILE 274 ? A ILE 303 
179  1 Y 1 A THR 275 ? A THR 304 
180  1 Y 1 A ASP 276 ? A ASP 305 
181  1 Y 1 A GLN 453 ? A GLN 482 
182  1 Y 1 A GLU 454 ? A GLU 483 
183  1 Y 1 A LYS 455 ? A LYS 484 
184  1 Y 1 A TYR 456 ? A TYR 485 
185  1 Y 1 A ILE 457 ? A ILE 486 
186  1 Y 1 A SER 458 ? A SER 487 
187  1 Y 1 D MET -17 ? B MET 1   
188  1 Y 1 D ALA -16 ? B ALA 2   
189  1 Y 1 D ASP -15 ? B ASP 3   
190  1 Y 1 D LEU -14 ? B LEU 4   
191  1 Y 1 D ASN -13 ? B ASN 5   
192  1 Y 1 D TRP -12 ? B TRP 6   
193  1 Y 1 D ILE -11 ? B ILE 7   
194  1 Y 1 D SER -10 ? B SER 8   
195  1 Y 1 D ALA -9  ? B ALA 9   
196  1 Y 1 D GLY -8  ? B GLY 10  
197  1 Y 1 D HIS -7  ? B HIS 11  
198  1 Y 1 D ALA -6  ? B ALA 12  
199  1 Y 1 D ILE -5  ? B ILE 13  
200  1 Y 1 D ALA -4  ? B ALA 14  
201  1 Y 1 D ASP -3  ? B ASP 15  
202  1 Y 1 D VAL -2  ? B VAL 16  
203  1 Y 1 D GLY -1  ? B GLY 17  
204  1 Y 1 D THR 0   ? B THR 18  
205  1 Y 1 D MET 1   ? B MET 19  
206  1 Y 1 D ALA 2   ? B ALA 20  
207  1 Y 1 D GLU 3   ? B GLU 21  
208  1 Y 1 D LEU 4   ? B LEU 22  
209  1 Y 1 D LYS 5   ? B LYS 23  
210  1 Y 1 D LEU 6   ? B LEU 24  
211  1 Y 1 D SER 7   ? B SER 25  
212  1 Y 1 D GLU 8   ? B GLU 26  
213  1 Y 1 D SER 9   ? B SER 27  
214  1 Y 1 D ARG 10  ? B ARG 28  
215  1 Y 1 D ASP 11  ? B ASP 29  
216  1 Y 1 D LEU 12  ? B LEU 30  
217  1 Y 1 D THR 13  ? B THR 31  
218  1 Y 1 D ARG 14  ? B ARG 32  
219  1 Y 1 D VAL 15  ? B VAL 33  
220  1 Y 1 D GLU 16  ? B GLU 34  
221  1 Y 1 D ARG 17  ? B ARG 35  
222  1 Y 1 D ILE 18  ? B ILE 36  
223  1 Y 1 D GLY 19  ? B GLY 37  
224  1 Y 1 D ALA 20  ? B ALA 38  
225  1 Y 1 D HIS 21  ? B HIS 39  
226  1 Y 1 D SER 22  ? B SER 40  
227  1 Y 1 D HIS 23  ? B HIS 41  
228  1 Y 1 D ILE 24  ? B ILE 42  
229  1 Y 1 D ARG 25  ? B ARG 43  
230  1 Y 1 D GLY 26  ? B GLY 44  
231  1 Y 1 D LEU 27  ? B LEU 45  
232  1 Y 1 D GLY 28  ? B GLY 46  
233  1 Y 1 D LEU 29  ? B LEU 47  
234  1 Y 1 D ASP 30  ? B ASP 48  
235  1 Y 1 D SER 31  ? B SER 49  
236  1 Y 1 D ALA 32  ? B ALA 50  
237  1 Y 1 D LEU 33  ? B LEU 51  
238  1 Y 1 D GLU 34  ? B GLU 52  
239  1 Y 1 D PRO 35  ? B PRO 53  
240  1 Y 1 D ARG 36  ? B ARG 54  
241  1 Y 1 D ALA 37  ? B ALA 55  
242  1 Y 1 D VAL 38  ? B VAL 56  
243  1 Y 1 D SER 39  ? B SER 57  
244  1 Y 1 D GLU 40  ? B GLU 58  
245  1 Y 1 D GLY 41  ? B GLY 59  
246  1 Y 1 D MET 42  ? B MET 60  
247  1 Y 1 D VAL 43  ? B VAL 61  
248  1 Y 1 D GLY 44  ? B GLY 62  
249  1 Y 1 D ILE 127 ? B ILE 145 
250  1 Y 1 D LYS 128 ? B LYS 146 
251  1 Y 1 D GLU 129 ? B GLU 147 
252  1 Y 1 D GLU 130 ? B GLU 148 
253  1 Y 1 D THR 131 ? B THR 149 
254  1 Y 1 D GLU 132 ? B GLU 150 
255  1 Y 1 D VAL 133 ? B VAL 151 
256  1 Y 1 D ILE 134 ? B ILE 152 
257  1 Y 1 D GLU 135 ? B GLU 153 
258  1 Y 1 D GLY 136 ? B GLY 154 
259  1 Y 1 D GLU 137 ? B GLU 155 
260  1 Y 1 D VAL 138 ? B VAL 156 
261  1 Y 1 D VAL 139 ? B VAL 157 
262  1 Y 1 D GLU 140 ? B GLU 158 
263  1 Y 1 D VAL 141 ? B VAL 159 
264  1 Y 1 D GLN 142 ? B GLN 160 
265  1 Y 1 D ILE 143 ? B ILE 161 
266  1 Y 1 D ASP 144 ? B ASP 162 
267  1 Y 1 D ARG 145 ? B ARG 163 
268  1 Y 1 D PRO 146 ? B PRO 164 
269  1 Y 1 D ALA 147 ? B ALA 165 
270  1 Y 1 D SER 148 ? B SER 166 
271  1 Y 1 D SER 149 ? B SER 167 
272  1 Y 1 D GLY 150 ? B GLY 168 
273  1 Y 1 D VAL 151 ? B VAL 169 
274  1 Y 1 D ALA 152 ? B ALA 170 
275  1 Y 1 D SER 153 ? B SER 171 
276  1 Y 1 D LYS 154 ? B LYS 172 
277  1 Y 1 D SER 155 ? B SER 173 
278  1 Y 1 D GLY 156 ? B GLY 174 
279  1 Y 1 D LYS 157 ? B LYS 175 
280  1 Y 1 D MET 158 ? B MET 176 
281  1 Y 1 D THR 159 ? B THR 177 
282  1 Y 1 D MET 160 ? B MET 178 
283  1 Y 1 D LYS 161 ? B LYS 179 
284  1 Y 1 D THR 162 ? B THR 180 
285  1 Y 1 D THR 163 ? B THR 181 
286  1 Y 1 D ASP 164 ? B ASP 182 
287  1 Y 1 D MET 165 ? B MET 183 
288  1 Y 1 D GLU 166 ? B GLU 184 
289  1 Y 1 D THR 167 ? B THR 185 
290  1 Y 1 D VAL 168 ? B VAL 186 
291  1 Y 1 D TYR 169 ? B TYR 187 
292  1 Y 1 D ASP 170 ? B ASP 188 
293  1 Y 1 D MET 171 ? B MET 189 
294  1 Y 1 D GLY 172 ? B GLY 190 
295  1 Y 1 D ALA 173 ? B ALA 191 
296  1 Y 1 D LYS 174 ? B LYS 192 
297  1 Y 1 D MET 175 ? B MET 193 
298  1 Y 1 D ILE 176 ? B ILE 194 
299  1 Y 1 D GLU 177 ? B GLU 195 
300  1 Y 1 D ALA 178 ? B ALA 196 
301  1 Y 1 D LEU 179 ? B LEU 197 
302  1 Y 1 D ASN 180 ? B ASN 198 
303  1 Y 1 D LYS 181 ? B LYS 199 
304  1 Y 1 D GLU 182 ? B GLU 200 
305  1 Y 1 D LYS 183 ? B LYS 201 
306  1 Y 1 D VAL 184 ? B VAL 202 
307  1 Y 1 D GLN 185 ? B GLN 203 
308  1 Y 1 D SER 186 ? B SER 204 
309  1 Y 1 D GLY 187 ? B GLY 205 
310  1 Y 1 D ASP 188 ? B ASP 206 
311  1 Y 1 D VAL 189 ? B VAL 207 
312  1 Y 1 D ILE 190 ? B ILE 208 
313  1 Y 1 D ALA 191 ? B ALA 209 
314  1 Y 1 D ILE 192 ? B ILE 210 
315  1 Y 1 D ASP 193 ? B ASP 211 
316  1 Y 1 D LYS 194 ? B LYS 212 
317  1 Y 1 D ALA 195 ? B ALA 213 
318  1 Y 1 D THR 196 ? B THR 214 
319  1 Y 1 D GLY 197 ? B GLY 215 
320  1 Y 1 D LYS 198 ? B LYS 216 
321  1 Y 1 D ILE 199 ? B ILE 217 
322  1 Y 1 D THR 200 ? B THR 218 
323  1 Y 1 D LYS 201 ? B LYS 219 
324  1 Y 1 D LEU 202 ? B LEU 220 
325  1 Y 1 D GLY 203 ? B GLY 221 
326  1 Y 1 D ARG 204 ? B ARG 222 
327  1 Y 1 D SER 205 ? B SER 223 
328  1 Y 1 D PHE 206 ? B PHE 224 
329  1 Y 1 D SER 207 ? B SER 225 
330  1 Y 1 D ARG 208 ? B ARG 226 
331  1 Y 1 D SER 209 ? B SER 227 
332  1 Y 1 D ARG 210 ? B ARG 228 
333  1 Y 1 D ASP 211 ? B ASP 229 
334  1 Y 1 D TYR 212 ? B TYR 230 
335  1 Y 1 D ASP 213 ? B ASP 231 
336  1 Y 1 D ALA 214 ? B ALA 232 
337  1 Y 1 D MET 215 ? B MET 233 
338  1 Y 1 D GLY 216 ? B GLY 234 
339  1 Y 1 D ALA 217 ? B ALA 235 
340  1 Y 1 D GLN 218 ? B GLN 236 
341  1 Y 1 D THR 219 ? B THR 237 
342  1 Y 1 D LYS 220 ? B LYS 238 
343  1 Y 1 D PHE 221 ? B PHE 239 
344  1 Y 1 D VAL 222 ? B VAL 240 
345  1 Y 1 D GLN 223 ? B GLN 241 
346  1 Y 1 D CYS 224 ? B CYS 242 
347  1 Y 1 D PRO 225 ? B PRO 243 
348  1 Y 1 D GLU 226 ? B GLU 244 
349  1 Y 1 D GLY 227 ? B GLY 245 
350  1 Y 1 D GLU 228 ? B GLU 246 
351  1 Y 1 D LEU 229 ? B LEU 247 
352  1 Y 1 D GLN 230 ? B GLN 248 
353  1 Y 1 D LYS 231 ? B LYS 249 
354  1 Y 1 D ARG 232 ? B ARG 250 
355  1 Y 1 D LYS 233 ? B LYS 251 
356  1 Y 1 D GLU 234 ? B GLU 252 
357  1 Y 1 D VAL 235 ? B VAL 253 
358  1 Y 1 D VAL 236 ? B VAL 254 
359  1 Y 1 D HIS 237 ? B HIS 255 
360  1 Y 1 D ARG 250 ? B ARG 268 
361  1 Y 1 D THR 251 ? B THR 269 
362  1 Y 1 D GLN 252 ? B GLN 270 
363  1 Y 1 D GLY 253 ? B GLY 271 
364  1 Y 1 D PHE 254 ? B PHE 272 
365  1 Y 1 D LEU 255 ? B LEU 273 
366  1 Y 1 D ALA 256 ? B ALA 274 
367  1 Y 1 D LEU 257 ? B LEU 275 
368  1 Y 1 D PHE 258 ? B PHE 276 
369  1 Y 1 D THR 259 ? B THR 277 
370  1 Y 1 D GLY 260 ? B GLY 278 
371  1 Y 1 D ASP 261 ? B ASP 279 
372  1 Y 1 D PHE 449 ? B PHE 467 
373  1 Y 1 D SER 450 ? B SER 468 
374  1 Y 1 D GLU 451 ? B GLU 469 
375  1 Y 1 D PRO 452 ? B PRO 470 
376  1 Y 1 D ILE 453 ? B ILE 471 
377  1 Y 1 D LYS 454 ? B LYS 472 
378  1 Y 1 D ASN 455 ? B ASN 473 
379  1 Y 1 D ASP 456 ? B ASP 474 
380  1 Y 1 D GLU 457 ? B GLU 475 
381  1 Y 1 D ALA 458 ? B ALA 476 
382  1 Y 1 D ALA 459 ? B ALA 477 
383  1 Y 1 D ALA 460 ? B ALA 478 
384  1 Y 1 D GLU 461 ? B GLU 479 
385  1 Y 1 D ASP 462 ? B ASP 480 
386  1 Y 1 D GLU 463 ? B GLU 481 
387  1 Y 1 D GLN 464 ? B GLN 482 
388  1 Y 1 D ASP 465 ? B ASP 483 
389  1 Y 1 D ALA 466 ? B ALA 484 
390  1 Y 1 D MET 467 ? B MET 485 
391  1 Y 1 D GLN 468 ? B GLN 486 
392  1 Y 1 D ILE 469 ? B ILE 487 
393  1 Y 1 C MET -28 ? C MET 1   
394  1 Y 1 C GLY -27 ? C GLY 2   
395  1 Y 1 C SER -26 ? C SER 3   
396  1 Y 1 C SER -25 ? C SER 4   
397  1 Y 1 C HIS -24 ? C HIS 5   
398  1 Y 1 C HIS -23 ? C HIS 6   
399  1 Y 1 C HIS -22 ? C HIS 7   
400  1 Y 1 C HIS -21 ? C HIS 8   
401  1 Y 1 C HIS -20 ? C HIS 9   
402  1 Y 1 C HIS -19 ? C HIS 10  
403  1 Y 1 C HIS -18 ? C HIS 11  
404  1 Y 1 C HIS -17 ? C HIS 12  
405  1 Y 1 C SER -16 ? C SER 13  
406  1 Y 1 C SER -15 ? C SER 14  
407  1 Y 1 C GLY -14 ? C GLY 15  
408  1 Y 1 C GLU -13 ? C GLU 16  
409  1 Y 1 C ASN -12 ? C ASN 17  
410  1 Y 1 C LEU -11 ? C LEU 18  
411  1 Y 1 C TYR -10 ? C TYR 19  
412  1 Y 1 C PHE -9  ? C PHE 20  
413  1 Y 1 C GLN -8  ? C GLN 21  
414  1 Y 1 C GLY -7  ? C GLY 22  
415  1 Y 1 C SER -6  ? C SER 23  
416  1 Y 1 C HIS -5  ? C HIS 24  
417  1 Y 1 C MET -4  ? C MET 25  
418  1 Y 1 C LEU -3  ? C LEU 26  
419  1 Y 1 C GLU -2  ? C GLU 27  
420  1 Y 1 C ASP -1  ? C ASP 28  
421  1 Y 1 C PRO 0   ? C PRO 29  
422  1 Y 1 C MET 1   ? C MET 30  
423  1 Y 1 C GLU 2   ? C GLU 31  
424  1 Y 1 C LYS 3   ? C LYS 32  
425  1 Y 1 C VAL 4   ? C VAL 33  
426  1 Y 1 C LYS 5   ? C LYS 34  
427  1 Y 1 C ILE 6   ? C ILE 35  
428  1 Y 1 C GLU 7   ? C GLU 36  
429  1 Y 1 C GLU 8   ? C GLU 37  
430  1 Y 1 C ILE 9   ? C ILE 38  
431  1 Y 1 C GLN 10  ? C GLN 39  
432  1 Y 1 C SER 11  ? C SER 40  
433  1 Y 1 C THR 12  ? C THR 41  
434  1 Y 1 C ALA 13  ? C ALA 42  
435  1 Y 1 C LYS 14  ? C LYS 43  
436  1 Y 1 C LYS 15  ? C LYS 44  
437  1 Y 1 C GLN 16  ? C GLN 45  
438  1 Y 1 C ARG 17  ? C ARG 46  
439  1 Y 1 C GLU 129 ? C GLU 158 
440  1 Y 1 C THR 130 ? C THR 159 
441  1 Y 1 C LYS 131 ? C LYS 160 
442  1 Y 1 C GLU 132 ? C GLU 161 
443  1 Y 1 C VAL 133 ? C VAL 162 
444  1 Y 1 C TYR 134 ? C TYR 163 
445  1 Y 1 C GLU 135 ? C GLU 164 
446  1 Y 1 C GLY 136 ? C GLY 165 
447  1 Y 1 C GLU 137 ? C GLU 166 
448  1 Y 1 C VAL 138 ? C VAL 167 
449  1 Y 1 C THR 139 ? C THR 168 
450  1 Y 1 C GLU 140 ? C GLU 169 
451  1 Y 1 C LEU 141 ? C LEU 170 
452  1 Y 1 C SER 142 ? C SER 171 
453  1 Y 1 C PRO 143 ? C PRO 172 
454  1 Y 1 C GLU 144 ? C GLU 173 
455  1 Y 1 C GLU 145 ? C GLU 174 
456  1 Y 1 C THR 146 ? C THR 175 
457  1 Y 1 C GLU 147 ? C GLU 176 
458  1 Y 1 C SER 148 ? C SER 177 
459  1 Y 1 C LEU 149 ? C LEU 178 
460  1 Y 1 C THR 150 ? C THR 179 
461  1 Y 1 C GLY 151 ? C GLY 180 
462  1 Y 1 C GLY 152 ? C GLY 181 
463  1 Y 1 C TYR 153 ? C TYR 182 
464  1 Y 1 C GLY 154 ? C GLY 183 
465  1 Y 1 C LYS 155 ? C LYS 184 
466  1 Y 1 C SER 156 ? C SER 185 
467  1 Y 1 C ILE 157 ? C ILE 186 
468  1 Y 1 C SER 158 ? C SER 187 
469  1 Y 1 C HIS 159 ? C HIS 188 
470  1 Y 1 C VAL 160 ? C VAL 189 
471  1 Y 1 C VAL 161 ? C VAL 190 
472  1 Y 1 C ILE 162 ? C ILE 191 
473  1 Y 1 C THR 163 ? C THR 192 
474  1 Y 1 C LEU 164 ? C LEU 193 
475  1 Y 1 C LYS 165 ? C LYS 194 
476  1 Y 1 C THR 166 ? C THR 195 
477  1 Y 1 C VAL 167 ? C VAL 196 
478  1 Y 1 C LYS 168 ? C LYS 197 
479  1 Y 1 C GLY 169 ? C GLY 198 
480  1 Y 1 C THR 170 ? C THR 199 
481  1 Y 1 C LYS 171 ? C LYS 200 
482  1 Y 1 C HIS 172 ? C HIS 201 
483  1 Y 1 C LEU 173 ? C LEU 202 
484  1 Y 1 C LYS 174 ? C LYS 203 
485  1 Y 1 C LEU 175 ? C LEU 204 
486  1 Y 1 C ASP 176 ? C ASP 205 
487  1 Y 1 C PRO 177 ? C PRO 206 
488  1 Y 1 C THR 178 ? C THR 207 
489  1 Y 1 C ILE 179 ? C ILE 208 
490  1 Y 1 C TYR 180 ? C TYR 209 
491  1 Y 1 C ASP 181 ? C ASP 210 
492  1 Y 1 C ALA 182 ? C ALA 211 
493  1 Y 1 C LEU 183 ? C LEU 212 
494  1 Y 1 C ILE 184 ? C ILE 213 
495  1 Y 1 C LYS 185 ? C LYS 214 
496  1 Y 1 C GLU 186 ? C GLU 215 
497  1 Y 1 C LYS 187 ? C LYS 216 
498  1 Y 1 C VAL 188 ? C VAL 217 
499  1 Y 1 C ALA 189 ? C ALA 218 
500  1 Y 1 C VAL 190 ? C VAL 219 
501  1 Y 1 C GLY 191 ? C GLY 220 
502  1 Y 1 C ASP 192 ? C ASP 221 
503  1 Y 1 C VAL 193 ? C VAL 222 
504  1 Y 1 C ILE 194 ? C ILE 223 
505  1 Y 1 C TYR 195 ? C TYR 224 
506  1 Y 1 C ILE 196 ? C ILE 225 
507  1 Y 1 C GLU 197 ? C GLU 226 
508  1 Y 1 C ALA 198 ? C ALA 227 
509  1 Y 1 C ASN 199 ? C ASN 228 
510  1 Y 1 C SER 200 ? C SER 229 
511  1 Y 1 C GLY 201 ? C GLY 230 
512  1 Y 1 C ALA 202 ? C ALA 231 
513  1 Y 1 C VAL 203 ? C VAL 232 
514  1 Y 1 C LYS 204 ? C LYS 233 
515  1 Y 1 C ARG 205 ? C ARG 234 
516  1 Y 1 C VAL 206 ? C VAL 235 
517  1 Y 1 C GLY 207 ? C GLY 236 
518  1 Y 1 C ARG 208 ? C ARG 237 
519  1 Y 1 C SER 209 ? C SER 238 
520  1 Y 1 C ASP 210 ? C ASP 239 
521  1 Y 1 C ALA 211 ? C ALA 240 
522  1 Y 1 C PHE 212 ? C PHE 241 
523  1 Y 1 C ALA 213 ? C ALA 242 
524  1 Y 1 C THR 214 ? C THR 243 
525  1 Y 1 C GLU 215 ? C GLU 244 
526  1 Y 1 C PHE 216 ? C PHE 245 
527  1 Y 1 C ASP 217 ? C ASP 246 
528  1 Y 1 C LEU 218 ? C LEU 247 
529  1 Y 1 C GLU 219 ? C GLU 248 
530  1 Y 1 C ALA 220 ? C ALA 249 
531  1 Y 1 C GLU 221 ? C GLU 250 
532  1 Y 1 C GLU 222 ? C GLU 251 
533  1 Y 1 C TYR 223 ? C TYR 252 
534  1 Y 1 C VAL 224 ? C VAL 253 
535  1 Y 1 C PRO 225 ? C PRO 254 
536  1 Y 1 C LEU 226 ? C LEU 255 
537  1 Y 1 C PRO 227 ? C PRO 256 
538  1 Y 1 C LYS 228 ? C LYS 257 
539  1 Y 1 C GLY 229 ? C GLY 258 
540  1 Y 1 C GLU 230 ? C GLU 259 
541  1 Y 1 C VAL 231 ? C VAL 260 
542  1 Y 1 C HIS 232 ? C HIS 261 
543  1 Y 1 C LYS 233 ? C LYS 262 
544  1 Y 1 C LYS 234 ? C LYS 263 
545  1 Y 1 C LYS 235 ? C LYS 264 
546  1 Y 1 C GLU 236 ? C GLU 265 
547  1 Y 1 C ILE 237 ? C ILE 266 
548  1 Y 1 C ARG 252 ? C ARG 281 
549  1 Y 1 C PRO 253 ? C PRO 282 
550  1 Y 1 C GLN 254 ? C GLN 283 
551  1 Y 1 C GLY 255 ? C GLY 284 
552  1 Y 1 C GLY 256 ? C GLY 285 
553  1 Y 1 C GLN 257 ? C GLN 286 
554  1 Y 1 C ASP 258 ? C ASP 287 
555  1 Y 1 C ILE 259 ? C ILE 288 
556  1 Y 1 C LEU 260 ? C LEU 289 
557  1 Y 1 C SER 261 ? C SER 290 
558  1 Y 1 C LEU 262 ? C LEU 291 
559  1 Y 1 C MET 263 ? C MET 292 
560  1 Y 1 C GLY 264 ? C GLY 293 
561  1 Y 1 C GLN 265 ? C GLN 294 
562  1 Y 1 C MET 266 ? C MET 295 
563  1 Y 1 C MET 267 ? C MET 296 
564  1 Y 1 C LYS 268 ? C LYS 297 
565  1 Y 1 C PRO 269 ? C PRO 298 
566  1 Y 1 C ARG 270 ? C ARG 299 
567  1 Y 1 C LYS 271 ? C LYS 300 
568  1 Y 1 C THR 272 ? C THR 301 
569  1 Y 1 C GLU 273 ? C GLU 302 
570  1 Y 1 C ILE 274 ? C ILE 303 
571  1 Y 1 C THR 275 ? C THR 304 
572  1 Y 1 C ASP 276 ? C ASP 305 
573  1 Y 1 C GLN 453 ? C GLN 482 
574  1 Y 1 C GLU 454 ? C GLU 483 
575  1 Y 1 C LYS 455 ? C LYS 484 
576  1 Y 1 C TYR 456 ? C TYR 485 
577  1 Y 1 C ILE 457 ? C ILE 486 
578  1 Y 1 C SER 458 ? C SER 487 
579  1 Y 1 B MET -28 ? D MET 1   
580  1 Y 1 B GLY -27 ? D GLY 2   
581  1 Y 1 B SER -26 ? D SER 3   
582  1 Y 1 B SER -25 ? D SER 4   
583  1 Y 1 B HIS -24 ? D HIS 5   
584  1 Y 1 B HIS -23 ? D HIS 6   
585  1 Y 1 B HIS -22 ? D HIS 7   
586  1 Y 1 B HIS -21 ? D HIS 8   
587  1 Y 1 B HIS -20 ? D HIS 9   
588  1 Y 1 B HIS -19 ? D HIS 10  
589  1 Y 1 B HIS -18 ? D HIS 11  
590  1 Y 1 B HIS -17 ? D HIS 12  
591  1 Y 1 B SER -16 ? D SER 13  
592  1 Y 1 B SER -15 ? D SER 14  
593  1 Y 1 B GLY -14 ? D GLY 15  
594  1 Y 1 B GLU -13 ? D GLU 16  
595  1 Y 1 B ASN -12 ? D ASN 17  
596  1 Y 1 B LEU -11 ? D LEU 18  
597  1 Y 1 B TYR -10 ? D TYR 19  
598  1 Y 1 B PHE -9  ? D PHE 20  
599  1 Y 1 B GLN -8  ? D GLN 21  
600  1 Y 1 B GLY -7  ? D GLY 22  
601  1 Y 1 B SER -6  ? D SER 23  
602  1 Y 1 B HIS -5  ? D HIS 24  
603  1 Y 1 B MET -4  ? D MET 25  
604  1 Y 1 B LEU -3  ? D LEU 26  
605  1 Y 1 B GLU -2  ? D GLU 27  
606  1 Y 1 B ASP -1  ? D ASP 28  
607  1 Y 1 B PRO 0   ? D PRO 29  
608  1 Y 1 B MET 1   ? D MET 30  
609  1 Y 1 B GLU 2   ? D GLU 31  
610  1 Y 1 B LYS 3   ? D LYS 32  
611  1 Y 1 B VAL 4   ? D VAL 33  
612  1 Y 1 B LYS 5   ? D LYS 34  
613  1 Y 1 B ILE 6   ? D ILE 35  
614  1 Y 1 B GLU 7   ? D GLU 36  
615  1 Y 1 B GLU 8   ? D GLU 37  
616  1 Y 1 B ILE 9   ? D ILE 38  
617  1 Y 1 B GLN 10  ? D GLN 39  
618  1 Y 1 B SER 11  ? D SER 40  
619  1 Y 1 B THR 12  ? D THR 41  
620  1 Y 1 B ALA 13  ? D ALA 42  
621  1 Y 1 B LYS 14  ? D LYS 43  
622  1 Y 1 B LYS 15  ? D LYS 44  
623  1 Y 1 B GLN 16  ? D GLN 45  
624  1 Y 1 B ARG 17  ? D ARG 46  
625  1 Y 1 B GLU 129 ? D GLU 158 
626  1 Y 1 B THR 130 ? D THR 159 
627  1 Y 1 B LYS 131 ? D LYS 160 
628  1 Y 1 B GLU 132 ? D GLU 161 
629  1 Y 1 B VAL 133 ? D VAL 162 
630  1 Y 1 B TYR 134 ? D TYR 163 
631  1 Y 1 B GLU 135 ? D GLU 164 
632  1 Y 1 B GLY 136 ? D GLY 165 
633  1 Y 1 B GLU 137 ? D GLU 166 
634  1 Y 1 B VAL 138 ? D VAL 167 
635  1 Y 1 B THR 139 ? D THR 168 
636  1 Y 1 B GLU 140 ? D GLU 169 
637  1 Y 1 B LEU 141 ? D LEU 170 
638  1 Y 1 B SER 142 ? D SER 171 
639  1 Y 1 B PRO 143 ? D PRO 172 
640  1 Y 1 B GLU 144 ? D GLU 173 
641  1 Y 1 B GLU 145 ? D GLU 174 
642  1 Y 1 B THR 146 ? D THR 175 
643  1 Y 1 B GLU 147 ? D GLU 176 
644  1 Y 1 B SER 148 ? D SER 177 
645  1 Y 1 B LEU 149 ? D LEU 178 
646  1 Y 1 B THR 150 ? D THR 179 
647  1 Y 1 B GLY 151 ? D GLY 180 
648  1 Y 1 B GLY 152 ? D GLY 181 
649  1 Y 1 B TYR 153 ? D TYR 182 
650  1 Y 1 B GLY 154 ? D GLY 183 
651  1 Y 1 B LYS 155 ? D LYS 184 
652  1 Y 1 B SER 156 ? D SER 185 
653  1 Y 1 B ILE 157 ? D ILE 186 
654  1 Y 1 B SER 158 ? D SER 187 
655  1 Y 1 B HIS 159 ? D HIS 188 
656  1 Y 1 B VAL 160 ? D VAL 189 
657  1 Y 1 B VAL 161 ? D VAL 190 
658  1 Y 1 B ILE 162 ? D ILE 191 
659  1 Y 1 B THR 163 ? D THR 192 
660  1 Y 1 B LEU 164 ? D LEU 193 
661  1 Y 1 B LYS 165 ? D LYS 194 
662  1 Y 1 B THR 166 ? D THR 195 
663  1 Y 1 B VAL 167 ? D VAL 196 
664  1 Y 1 B LYS 168 ? D LYS 197 
665  1 Y 1 B GLY 169 ? D GLY 198 
666  1 Y 1 B THR 170 ? D THR 199 
667  1 Y 1 B LYS 171 ? D LYS 200 
668  1 Y 1 B HIS 172 ? D HIS 201 
669  1 Y 1 B LEU 173 ? D LEU 202 
670  1 Y 1 B LYS 174 ? D LYS 203 
671  1 Y 1 B LEU 175 ? D LEU 204 
672  1 Y 1 B ASP 176 ? D ASP 205 
673  1 Y 1 B PRO 177 ? D PRO 206 
674  1 Y 1 B THR 178 ? D THR 207 
675  1 Y 1 B ILE 179 ? D ILE 208 
676  1 Y 1 B TYR 180 ? D TYR 209 
677  1 Y 1 B ASP 181 ? D ASP 210 
678  1 Y 1 B ALA 182 ? D ALA 211 
679  1 Y 1 B LEU 183 ? D LEU 212 
680  1 Y 1 B ILE 184 ? D ILE 213 
681  1 Y 1 B LYS 185 ? D LYS 214 
682  1 Y 1 B GLU 186 ? D GLU 215 
683  1 Y 1 B LYS 187 ? D LYS 216 
684  1 Y 1 B VAL 188 ? D VAL 217 
685  1 Y 1 B ALA 189 ? D ALA 218 
686  1 Y 1 B VAL 190 ? D VAL 219 
687  1 Y 1 B GLY 191 ? D GLY 220 
688  1 Y 1 B ASP 192 ? D ASP 221 
689  1 Y 1 B VAL 193 ? D VAL 222 
690  1 Y 1 B ILE 194 ? D ILE 223 
691  1 Y 1 B TYR 195 ? D TYR 224 
692  1 Y 1 B ILE 196 ? D ILE 225 
693  1 Y 1 B GLU 197 ? D GLU 226 
694  1 Y 1 B ALA 198 ? D ALA 227 
695  1 Y 1 B ASN 199 ? D ASN 228 
696  1 Y 1 B SER 200 ? D SER 229 
697  1 Y 1 B GLY 201 ? D GLY 230 
698  1 Y 1 B ALA 202 ? D ALA 231 
699  1 Y 1 B VAL 203 ? D VAL 232 
700  1 Y 1 B LYS 204 ? D LYS 233 
701  1 Y 1 B ARG 205 ? D ARG 234 
702  1 Y 1 B VAL 206 ? D VAL 235 
703  1 Y 1 B GLY 207 ? D GLY 236 
704  1 Y 1 B ARG 208 ? D ARG 237 
705  1 Y 1 B SER 209 ? D SER 238 
706  1 Y 1 B ASP 210 ? D ASP 239 
707  1 Y 1 B ALA 211 ? D ALA 240 
708  1 Y 1 B PHE 212 ? D PHE 241 
709  1 Y 1 B ALA 213 ? D ALA 242 
710  1 Y 1 B THR 214 ? D THR 243 
711  1 Y 1 B GLU 215 ? D GLU 244 
712  1 Y 1 B PHE 216 ? D PHE 245 
713  1 Y 1 B ASP 217 ? D ASP 246 
714  1 Y 1 B LEU 218 ? D LEU 247 
715  1 Y 1 B GLU 219 ? D GLU 248 
716  1 Y 1 B ALA 220 ? D ALA 249 
717  1 Y 1 B GLU 221 ? D GLU 250 
718  1 Y 1 B GLU 222 ? D GLU 251 
719  1 Y 1 B TYR 223 ? D TYR 252 
720  1 Y 1 B VAL 224 ? D VAL 253 
721  1 Y 1 B PRO 225 ? D PRO 254 
722  1 Y 1 B LEU 226 ? D LEU 255 
723  1 Y 1 B PRO 227 ? D PRO 256 
724  1 Y 1 B LYS 228 ? D LYS 257 
725  1 Y 1 B GLY 229 ? D GLY 258 
726  1 Y 1 B GLU 230 ? D GLU 259 
727  1 Y 1 B VAL 231 ? D VAL 260 
728  1 Y 1 B HIS 232 ? D HIS 261 
729  1 Y 1 B LYS 233 ? D LYS 262 
730  1 Y 1 B LYS 234 ? D LYS 263 
731  1 Y 1 B LYS 235 ? D LYS 264 
732  1 Y 1 B GLU 236 ? D GLU 265 
733  1 Y 1 B ILE 237 ? D ILE 266 
734  1 Y 1 B ARG 252 ? D ARG 281 
735  1 Y 1 B PRO 253 ? D PRO 282 
736  1 Y 1 B GLN 254 ? D GLN 283 
737  1 Y 1 B GLY 255 ? D GLY 284 
738  1 Y 1 B GLY 256 ? D GLY 285 
739  1 Y 1 B GLN 257 ? D GLN 286 
740  1 Y 1 B ASP 258 ? D ASP 287 
741  1 Y 1 B ILE 259 ? D ILE 288 
742  1 Y 1 B LEU 260 ? D LEU 289 
743  1 Y 1 B SER 261 ? D SER 290 
744  1 Y 1 B LEU 262 ? D LEU 291 
745  1 Y 1 B MET 263 ? D MET 292 
746  1 Y 1 B GLY 264 ? D GLY 293 
747  1 Y 1 B GLN 265 ? D GLN 294 
748  1 Y 1 B MET 266 ? D MET 295 
749  1 Y 1 B MET 267 ? D MET 296 
750  1 Y 1 B LYS 268 ? D LYS 297 
751  1 Y 1 B PRO 269 ? D PRO 298 
752  1 Y 1 B ARG 270 ? D ARG 299 
753  1 Y 1 B LYS 271 ? D LYS 300 
754  1 Y 1 B THR 272 ? D THR 301 
755  1 Y 1 B GLU 273 ? D GLU 302 
756  1 Y 1 B ILE 274 ? D ILE 303 
757  1 Y 1 B THR 275 ? D THR 304 
758  1 Y 1 B ASP 276 ? D ASP 305 
759  1 Y 1 B GLN 453 ? D GLN 482 
760  1 Y 1 B GLU 454 ? D GLU 483 
761  1 Y 1 B LYS 455 ? D LYS 484 
762  1 Y 1 B TYR 456 ? D TYR 485 
763  1 Y 1 B ILE 457 ? D ILE 486 
764  1 Y 1 B SER 458 ? D SER 487 
765  1 Y 1 F MET -17 ? E MET 1   
766  1 Y 1 F ALA -16 ? E ALA 2   
767  1 Y 1 F ASP -15 ? E ASP 3   
768  1 Y 1 F LEU -14 ? E LEU 4   
769  1 Y 1 F ASN -13 ? E ASN 5   
770  1 Y 1 F TRP -12 ? E TRP 6   
771  1 Y 1 F ILE -11 ? E ILE 7   
772  1 Y 1 F SER -10 ? E SER 8   
773  1 Y 1 F ALA -9  ? E ALA 9   
774  1 Y 1 F GLY -8  ? E GLY 10  
775  1 Y 1 F HIS -7  ? E HIS 11  
776  1 Y 1 F ALA -6  ? E ALA 12  
777  1 Y 1 F ILE -5  ? E ILE 13  
778  1 Y 1 F ALA -4  ? E ALA 14  
779  1 Y 1 F ASP -3  ? E ASP 15  
780  1 Y 1 F VAL -2  ? E VAL 16  
781  1 Y 1 F GLY -1  ? E GLY 17  
782  1 Y 1 F THR 0   ? E THR 18  
783  1 Y 1 F MET 1   ? E MET 19  
784  1 Y 1 F ALA 2   ? E ALA 20  
785  1 Y 1 F GLU 3   ? E GLU 21  
786  1 Y 1 F LEU 4   ? E LEU 22  
787  1 Y 1 F LYS 5   ? E LYS 23  
788  1 Y 1 F LEU 6   ? E LEU 24  
789  1 Y 1 F SER 7   ? E SER 25  
790  1 Y 1 F GLU 8   ? E GLU 26  
791  1 Y 1 F SER 9   ? E SER 27  
792  1 Y 1 F ARG 10  ? E ARG 28  
793  1 Y 1 F ASP 11  ? E ASP 29  
794  1 Y 1 F LEU 12  ? E LEU 30  
795  1 Y 1 F THR 13  ? E THR 31  
796  1 Y 1 F ARG 14  ? E ARG 32  
797  1 Y 1 F VAL 15  ? E VAL 33  
798  1 Y 1 F GLU 16  ? E GLU 34  
799  1 Y 1 F ARG 17  ? E ARG 35  
800  1 Y 1 F ILE 18  ? E ILE 36  
801  1 Y 1 F GLY 19  ? E GLY 37  
802  1 Y 1 F ALA 20  ? E ALA 38  
803  1 Y 1 F HIS 21  ? E HIS 39  
804  1 Y 1 F SER 22  ? E SER 40  
805  1 Y 1 F HIS 23  ? E HIS 41  
806  1 Y 1 F ILE 24  ? E ILE 42  
807  1 Y 1 F ARG 25  ? E ARG 43  
808  1 Y 1 F GLY 26  ? E GLY 44  
809  1 Y 1 F LEU 27  ? E LEU 45  
810  1 Y 1 F GLY 28  ? E GLY 46  
811  1 Y 1 F LEU 29  ? E LEU 47  
812  1 Y 1 F ASP 30  ? E ASP 48  
813  1 Y 1 F SER 31  ? E SER 49  
814  1 Y 1 F ALA 32  ? E ALA 50  
815  1 Y 1 F LEU 33  ? E LEU 51  
816  1 Y 1 F GLU 34  ? E GLU 52  
817  1 Y 1 F PRO 35  ? E PRO 53  
818  1 Y 1 F ARG 36  ? E ARG 54  
819  1 Y 1 F ALA 37  ? E ALA 55  
820  1 Y 1 F VAL 38  ? E VAL 56  
821  1 Y 1 F SER 39  ? E SER 57  
822  1 Y 1 F GLU 40  ? E GLU 58  
823  1 Y 1 F GLY 41  ? E GLY 59  
824  1 Y 1 F MET 42  ? E MET 60  
825  1 Y 1 F VAL 43  ? E VAL 61  
826  1 Y 1 F GLY 44  ? E GLY 62  
827  1 Y 1 F ILE 127 ? E ILE 145 
828  1 Y 1 F LYS 128 ? E LYS 146 
829  1 Y 1 F GLU 129 ? E GLU 147 
830  1 Y 1 F GLU 130 ? E GLU 148 
831  1 Y 1 F THR 131 ? E THR 149 
832  1 Y 1 F GLU 132 ? E GLU 150 
833  1 Y 1 F VAL 133 ? E VAL 151 
834  1 Y 1 F ILE 134 ? E ILE 152 
835  1 Y 1 F GLU 135 ? E GLU 153 
836  1 Y 1 F GLY 136 ? E GLY 154 
837  1 Y 1 F GLU 137 ? E GLU 155 
838  1 Y 1 F VAL 138 ? E VAL 156 
839  1 Y 1 F VAL 139 ? E VAL 157 
840  1 Y 1 F GLU 140 ? E GLU 158 
841  1 Y 1 F VAL 141 ? E VAL 159 
842  1 Y 1 F GLN 142 ? E GLN 160 
843  1 Y 1 F ILE 143 ? E ILE 161 
844  1 Y 1 F ASP 144 ? E ASP 162 
845  1 Y 1 F ARG 145 ? E ARG 163 
846  1 Y 1 F PRO 146 ? E PRO 164 
847  1 Y 1 F ALA 147 ? E ALA 165 
848  1 Y 1 F SER 148 ? E SER 166 
849  1 Y 1 F SER 149 ? E SER 167 
850  1 Y 1 F GLY 150 ? E GLY 168 
851  1 Y 1 F VAL 151 ? E VAL 169 
852  1 Y 1 F ALA 152 ? E ALA 170 
853  1 Y 1 F SER 153 ? E SER 171 
854  1 Y 1 F LYS 154 ? E LYS 172 
855  1 Y 1 F SER 155 ? E SER 173 
856  1 Y 1 F GLY 156 ? E GLY 174 
857  1 Y 1 F LYS 157 ? E LYS 175 
858  1 Y 1 F MET 158 ? E MET 176 
859  1 Y 1 F THR 159 ? E THR 177 
860  1 Y 1 F MET 160 ? E MET 178 
861  1 Y 1 F LYS 161 ? E LYS 179 
862  1 Y 1 F THR 162 ? E THR 180 
863  1 Y 1 F THR 163 ? E THR 181 
864  1 Y 1 F ASP 164 ? E ASP 182 
865  1 Y 1 F MET 165 ? E MET 183 
866  1 Y 1 F GLU 166 ? E GLU 184 
867  1 Y 1 F THR 167 ? E THR 185 
868  1 Y 1 F VAL 168 ? E VAL 186 
869  1 Y 1 F TYR 169 ? E TYR 187 
870  1 Y 1 F ASP 170 ? E ASP 188 
871  1 Y 1 F MET 171 ? E MET 189 
872  1 Y 1 F GLY 172 ? E GLY 190 
873  1 Y 1 F ALA 173 ? E ALA 191 
874  1 Y 1 F LYS 174 ? E LYS 192 
875  1 Y 1 F MET 175 ? E MET 193 
876  1 Y 1 F ILE 176 ? E ILE 194 
877  1 Y 1 F GLU 177 ? E GLU 195 
878  1 Y 1 F ALA 178 ? E ALA 196 
879  1 Y 1 F LEU 179 ? E LEU 197 
880  1 Y 1 F ASN 180 ? E ASN 198 
881  1 Y 1 F LYS 181 ? E LYS 199 
882  1 Y 1 F GLU 182 ? E GLU 200 
883  1 Y 1 F LYS 183 ? E LYS 201 
884  1 Y 1 F VAL 184 ? E VAL 202 
885  1 Y 1 F GLN 185 ? E GLN 203 
886  1 Y 1 F SER 186 ? E SER 204 
887  1 Y 1 F GLY 187 ? E GLY 205 
888  1 Y 1 F ASP 188 ? E ASP 206 
889  1 Y 1 F VAL 189 ? E VAL 207 
890  1 Y 1 F ILE 190 ? E ILE 208 
891  1 Y 1 F ALA 191 ? E ALA 209 
892  1 Y 1 F ILE 192 ? E ILE 210 
893  1 Y 1 F ASP 193 ? E ASP 211 
894  1 Y 1 F LYS 194 ? E LYS 212 
895  1 Y 1 F ALA 195 ? E ALA 213 
896  1 Y 1 F THR 196 ? E THR 214 
897  1 Y 1 F GLY 197 ? E GLY 215 
898  1 Y 1 F LYS 198 ? E LYS 216 
899  1 Y 1 F ILE 199 ? E ILE 217 
900  1 Y 1 F THR 200 ? E THR 218 
901  1 Y 1 F LYS 201 ? E LYS 219 
902  1 Y 1 F LEU 202 ? E LEU 220 
903  1 Y 1 F GLY 203 ? E GLY 221 
904  1 Y 1 F ARG 204 ? E ARG 222 
905  1 Y 1 F SER 205 ? E SER 223 
906  1 Y 1 F PHE 206 ? E PHE 224 
907  1 Y 1 F SER 207 ? E SER 225 
908  1 Y 1 F ARG 208 ? E ARG 226 
909  1 Y 1 F SER 209 ? E SER 227 
910  1 Y 1 F ARG 210 ? E ARG 228 
911  1 Y 1 F ASP 211 ? E ASP 229 
912  1 Y 1 F TYR 212 ? E TYR 230 
913  1 Y 1 F ASP 213 ? E ASP 231 
914  1 Y 1 F ALA 214 ? E ALA 232 
915  1 Y 1 F MET 215 ? E MET 233 
916  1 Y 1 F GLY 216 ? E GLY 234 
917  1 Y 1 F ALA 217 ? E ALA 235 
918  1 Y 1 F GLN 218 ? E GLN 236 
919  1 Y 1 F THR 219 ? E THR 237 
920  1 Y 1 F LYS 220 ? E LYS 238 
921  1 Y 1 F PHE 221 ? E PHE 239 
922  1 Y 1 F VAL 222 ? E VAL 240 
923  1 Y 1 F GLN 223 ? E GLN 241 
924  1 Y 1 F CYS 224 ? E CYS 242 
925  1 Y 1 F PRO 225 ? E PRO 243 
926  1 Y 1 F GLU 226 ? E GLU 244 
927  1 Y 1 F GLY 227 ? E GLY 245 
928  1 Y 1 F GLU 228 ? E GLU 246 
929  1 Y 1 F LEU 229 ? E LEU 247 
930  1 Y 1 F GLN 230 ? E GLN 248 
931  1 Y 1 F LYS 231 ? E LYS 249 
932  1 Y 1 F ARG 232 ? E ARG 250 
933  1 Y 1 F LYS 233 ? E LYS 251 
934  1 Y 1 F GLU 234 ? E GLU 252 
935  1 Y 1 F VAL 235 ? E VAL 253 
936  1 Y 1 F VAL 236 ? E VAL 254 
937  1 Y 1 F HIS 237 ? E HIS 255 
938  1 Y 1 F ARG 250 ? E ARG 268 
939  1 Y 1 F THR 251 ? E THR 269 
940  1 Y 1 F GLN 252 ? E GLN 270 
941  1 Y 1 F GLY 253 ? E GLY 271 
942  1 Y 1 F PHE 254 ? E PHE 272 
943  1 Y 1 F LEU 255 ? E LEU 273 
944  1 Y 1 F ALA 256 ? E ALA 274 
945  1 Y 1 F LEU 257 ? E LEU 275 
946  1 Y 1 F PHE 258 ? E PHE 276 
947  1 Y 1 F THR 259 ? E THR 277 
948  1 Y 1 F GLY 260 ? E GLY 278 
949  1 Y 1 F ASP 261 ? E ASP 279 
950  1 Y 1 F PHE 449 ? E PHE 467 
951  1 Y 1 F SER 450 ? E SER 468 
952  1 Y 1 F GLU 451 ? E GLU 469 
953  1 Y 1 F PRO 452 ? E PRO 470 
954  1 Y 1 F ILE 453 ? E ILE 471 
955  1 Y 1 F LYS 454 ? E LYS 472 
956  1 Y 1 F ASN 455 ? E ASN 473 
957  1 Y 1 F ASP 456 ? E ASP 474 
958  1 Y 1 F GLU 457 ? E GLU 475 
959  1 Y 1 F ALA 458 ? E ALA 476 
960  1 Y 1 F ALA 459 ? E ALA 477 
961  1 Y 1 F ALA 460 ? E ALA 478 
962  1 Y 1 F GLU 461 ? E GLU 479 
963  1 Y 1 F ASP 462 ? E ASP 480 
964  1 Y 1 F GLU 463 ? E GLU 481 
965  1 Y 1 F GLN 464 ? E GLN 482 
966  1 Y 1 F ASP 465 ? E ASP 483 
967  1 Y 1 F ALA 466 ? E ALA 484 
968  1 Y 1 F MET 467 ? E MET 485 
969  1 Y 1 F GLN 468 ? E GLN 486 
970  1 Y 1 F ILE 469 ? E ILE 487 
971  1 Y 1 E MET -17 ? F MET 1   
972  1 Y 1 E ALA -16 ? F ALA 2   
973  1 Y 1 E ASP -15 ? F ASP 3   
974  1 Y 1 E LEU -14 ? F LEU 4   
975  1 Y 1 E ASN -13 ? F ASN 5   
976  1 Y 1 E TRP -12 ? F TRP 6   
977  1 Y 1 E ILE -11 ? F ILE 7   
978  1 Y 1 E SER -10 ? F SER 8   
979  1 Y 1 E ALA -9  ? F ALA 9   
980  1 Y 1 E GLY -8  ? F GLY 10  
981  1 Y 1 E HIS -7  ? F HIS 11  
982  1 Y 1 E ALA -6  ? F ALA 12  
983  1 Y 1 E ILE -5  ? F ILE 13  
984  1 Y 1 E ALA -4  ? F ALA 14  
985  1 Y 1 E ASP -3  ? F ASP 15  
986  1 Y 1 E VAL -2  ? F VAL 16  
987  1 Y 1 E GLY -1  ? F GLY 17  
988  1 Y 1 E THR 0   ? F THR 18  
989  1 Y 1 E MET 1   ? F MET 19  
990  1 Y 1 E ALA 2   ? F ALA 20  
991  1 Y 1 E GLU 3   ? F GLU 21  
992  1 Y 1 E LEU 4   ? F LEU 22  
993  1 Y 1 E LYS 5   ? F LYS 23  
994  1 Y 1 E LEU 6   ? F LEU 24  
995  1 Y 1 E SER 7   ? F SER 25  
996  1 Y 1 E GLU 8   ? F GLU 26  
997  1 Y 1 E SER 9   ? F SER 27  
998  1 Y 1 E ARG 10  ? F ARG 28  
999  1 Y 1 E ASP 11  ? F ASP 29  
1000 1 Y 1 E LEU 12  ? F LEU 30  
1001 1 Y 1 E THR 13  ? F THR 31  
1002 1 Y 1 E ARG 14  ? F ARG 32  
1003 1 Y 1 E VAL 15  ? F VAL 33  
1004 1 Y 1 E GLU 16  ? F GLU 34  
1005 1 Y 1 E ARG 17  ? F ARG 35  
1006 1 Y 1 E ILE 18  ? F ILE 36  
1007 1 Y 1 E GLY 19  ? F GLY 37  
1008 1 Y 1 E ALA 20  ? F ALA 38  
1009 1 Y 1 E HIS 21  ? F HIS 39  
1010 1 Y 1 E SER 22  ? F SER 40  
1011 1 Y 1 E HIS 23  ? F HIS 41  
1012 1 Y 1 E ILE 24  ? F ILE 42  
1013 1 Y 1 E ARG 25  ? F ARG 43  
1014 1 Y 1 E GLY 26  ? F GLY 44  
1015 1 Y 1 E LEU 27  ? F LEU 45  
1016 1 Y 1 E GLY 28  ? F GLY 46  
1017 1 Y 1 E LEU 29  ? F LEU 47  
1018 1 Y 1 E ASP 30  ? F ASP 48  
1019 1 Y 1 E SER 31  ? F SER 49  
1020 1 Y 1 E ALA 32  ? F ALA 50  
1021 1 Y 1 E LEU 33  ? F LEU 51  
1022 1 Y 1 E GLU 34  ? F GLU 52  
1023 1 Y 1 E PRO 35  ? F PRO 53  
1024 1 Y 1 E ARG 36  ? F ARG 54  
1025 1 Y 1 E ALA 37  ? F ALA 55  
1026 1 Y 1 E VAL 38  ? F VAL 56  
1027 1 Y 1 E SER 39  ? F SER 57  
1028 1 Y 1 E GLU 40  ? F GLU 58  
1029 1 Y 1 E GLY 41  ? F GLY 59  
1030 1 Y 1 E MET 42  ? F MET 60  
1031 1 Y 1 E VAL 43  ? F VAL 61  
1032 1 Y 1 E GLY 44  ? F GLY 62  
1033 1 Y 1 E ILE 127 ? F ILE 145 
1034 1 Y 1 E LYS 128 ? F LYS 146 
1035 1 Y 1 E GLU 129 ? F GLU 147 
1036 1 Y 1 E GLU 130 ? F GLU 148 
1037 1 Y 1 E THR 131 ? F THR 149 
1038 1 Y 1 E GLU 132 ? F GLU 150 
1039 1 Y 1 E VAL 133 ? F VAL 151 
1040 1 Y 1 E ILE 134 ? F ILE 152 
1041 1 Y 1 E GLU 135 ? F GLU 153 
1042 1 Y 1 E GLY 136 ? F GLY 154 
1043 1 Y 1 E GLU 137 ? F GLU 155 
1044 1 Y 1 E VAL 138 ? F VAL 156 
1045 1 Y 1 E VAL 139 ? F VAL 157 
1046 1 Y 1 E GLU 140 ? F GLU 158 
1047 1 Y 1 E VAL 141 ? F VAL 159 
1048 1 Y 1 E GLN 142 ? F GLN 160 
1049 1 Y 1 E ILE 143 ? F ILE 161 
1050 1 Y 1 E ASP 144 ? F ASP 162 
1051 1 Y 1 E ARG 145 ? F ARG 163 
1052 1 Y 1 E PRO 146 ? F PRO 164 
1053 1 Y 1 E ALA 147 ? F ALA 165 
1054 1 Y 1 E SER 148 ? F SER 166 
1055 1 Y 1 E SER 149 ? F SER 167 
1056 1 Y 1 E GLY 150 ? F GLY 168 
1057 1 Y 1 E VAL 151 ? F VAL 169 
1058 1 Y 1 E ALA 152 ? F ALA 170 
1059 1 Y 1 E SER 153 ? F SER 171 
1060 1 Y 1 E LYS 154 ? F LYS 172 
1061 1 Y 1 E SER 155 ? F SER 173 
1062 1 Y 1 E GLY 156 ? F GLY 174 
1063 1 Y 1 E LYS 157 ? F LYS 175 
1064 1 Y 1 E MET 158 ? F MET 176 
1065 1 Y 1 E THR 159 ? F THR 177 
1066 1 Y 1 E MET 160 ? F MET 178 
1067 1 Y 1 E LYS 161 ? F LYS 179 
1068 1 Y 1 E THR 162 ? F THR 180 
1069 1 Y 1 E THR 163 ? F THR 181 
1070 1 Y 1 E ASP 164 ? F ASP 182 
1071 1 Y 1 E MET 165 ? F MET 183 
1072 1 Y 1 E GLU 166 ? F GLU 184 
1073 1 Y 1 E THR 167 ? F THR 185 
1074 1 Y 1 E VAL 168 ? F VAL 186 
1075 1 Y 1 E TYR 169 ? F TYR 187 
1076 1 Y 1 E ASP 170 ? F ASP 188 
1077 1 Y 1 E MET 171 ? F MET 189 
1078 1 Y 1 E GLY 172 ? F GLY 190 
1079 1 Y 1 E ALA 173 ? F ALA 191 
1080 1 Y 1 E LYS 174 ? F LYS 192 
1081 1 Y 1 E MET 175 ? F MET 193 
1082 1 Y 1 E ILE 176 ? F ILE 194 
1083 1 Y 1 E GLU 177 ? F GLU 195 
1084 1 Y 1 E ALA 178 ? F ALA 196 
1085 1 Y 1 E LEU 179 ? F LEU 197 
1086 1 Y 1 E ASN 180 ? F ASN 198 
1087 1 Y 1 E LYS 181 ? F LYS 199 
1088 1 Y 1 E GLU 182 ? F GLU 200 
1089 1 Y 1 E LYS 183 ? F LYS 201 
1090 1 Y 1 E VAL 184 ? F VAL 202 
1091 1 Y 1 E GLN 185 ? F GLN 203 
1092 1 Y 1 E SER 186 ? F SER 204 
1093 1 Y 1 E GLY 187 ? F GLY 205 
1094 1 Y 1 E ASP 188 ? F ASP 206 
1095 1 Y 1 E VAL 189 ? F VAL 207 
1096 1 Y 1 E ILE 190 ? F ILE 208 
1097 1 Y 1 E ALA 191 ? F ALA 209 
1098 1 Y 1 E ILE 192 ? F ILE 210 
1099 1 Y 1 E ASP 193 ? F ASP 211 
1100 1 Y 1 E LYS 194 ? F LYS 212 
1101 1 Y 1 E ALA 195 ? F ALA 213 
1102 1 Y 1 E THR 196 ? F THR 214 
1103 1 Y 1 E GLY 197 ? F GLY 215 
1104 1 Y 1 E LYS 198 ? F LYS 216 
1105 1 Y 1 E ILE 199 ? F ILE 217 
1106 1 Y 1 E THR 200 ? F THR 218 
1107 1 Y 1 E LYS 201 ? F LYS 219 
1108 1 Y 1 E LEU 202 ? F LEU 220 
1109 1 Y 1 E GLY 203 ? F GLY 221 
1110 1 Y 1 E ARG 204 ? F ARG 222 
1111 1 Y 1 E SER 205 ? F SER 223 
1112 1 Y 1 E PHE 206 ? F PHE 224 
1113 1 Y 1 E SER 207 ? F SER 225 
1114 1 Y 1 E ARG 208 ? F ARG 226 
1115 1 Y 1 E SER 209 ? F SER 227 
1116 1 Y 1 E ARG 210 ? F ARG 228 
1117 1 Y 1 E ASP 211 ? F ASP 229 
1118 1 Y 1 E TYR 212 ? F TYR 230 
1119 1 Y 1 E ASP 213 ? F ASP 231 
1120 1 Y 1 E ALA 214 ? F ALA 232 
1121 1 Y 1 E MET 215 ? F MET 233 
1122 1 Y 1 E GLY 216 ? F GLY 234 
1123 1 Y 1 E ALA 217 ? F ALA 235 
1124 1 Y 1 E GLN 218 ? F GLN 236 
1125 1 Y 1 E THR 219 ? F THR 237 
1126 1 Y 1 E LYS 220 ? F LYS 238 
1127 1 Y 1 E PHE 221 ? F PHE 239 
1128 1 Y 1 E VAL 222 ? F VAL 240 
1129 1 Y 1 E GLN 223 ? F GLN 241 
1130 1 Y 1 E CYS 224 ? F CYS 242 
1131 1 Y 1 E PRO 225 ? F PRO 243 
1132 1 Y 1 E GLU 226 ? F GLU 244 
1133 1 Y 1 E GLY 227 ? F GLY 245 
1134 1 Y 1 E GLU 228 ? F GLU 246 
1135 1 Y 1 E LEU 229 ? F LEU 247 
1136 1 Y 1 E GLN 230 ? F GLN 248 
1137 1 Y 1 E LYS 231 ? F LYS 249 
1138 1 Y 1 E ARG 232 ? F ARG 250 
1139 1 Y 1 E LYS 233 ? F LYS 251 
1140 1 Y 1 E GLU 234 ? F GLU 252 
1141 1 Y 1 E VAL 235 ? F VAL 253 
1142 1 Y 1 E VAL 236 ? F VAL 254 
1143 1 Y 1 E HIS 237 ? F HIS 255 
1144 1 Y 1 E ARG 250 ? F ARG 268 
1145 1 Y 1 E THR 251 ? F THR 269 
1146 1 Y 1 E GLN 252 ? F GLN 270 
1147 1 Y 1 E GLY 253 ? F GLY 271 
1148 1 Y 1 E PHE 254 ? F PHE 272 
1149 1 Y 1 E LEU 255 ? F LEU 273 
1150 1 Y 1 E ALA 256 ? F ALA 274 
1151 1 Y 1 E LEU 257 ? F LEU 275 
1152 1 Y 1 E PHE 258 ? F PHE 276 
1153 1 Y 1 E THR 259 ? F THR 277 
1154 1 Y 1 E GLY 260 ? F GLY 278 
1155 1 Y 1 E ASP 261 ? F ASP 279 
1156 1 Y 1 E PHE 449 ? F PHE 467 
1157 1 Y 1 E SER 450 ? F SER 468 
1158 1 Y 1 E GLU 451 ? F GLU 469 
1159 1 Y 1 E PRO 452 ? F PRO 470 
1160 1 Y 1 E ILE 453 ? F ILE 471 
1161 1 Y 1 E LYS 454 ? F LYS 472 
1162 1 Y 1 E ASN 455 ? F ASN 473 
1163 1 Y 1 E ASP 456 ? F ASP 474 
1164 1 Y 1 E GLU 457 ? F GLU 475 
1165 1 Y 1 E ALA 458 ? F ALA 476 
1166 1 Y 1 E ALA 459 ? F ALA 477 
1167 1 Y 1 E ALA 460 ? F ALA 478 
1168 1 Y 1 E GLU 461 ? F GLU 479 
1169 1 Y 1 E ASP 462 ? F ASP 480 
1170 1 Y 1 E GLU 463 ? F GLU 481 
1171 1 Y 1 E GLN 464 ? F GLN 482 
1172 1 Y 1 E ASP 465 ? F ASP 483 
1173 1 Y 1 E ALA 466 ? F ALA 484 
1174 1 Y 1 E MET 467 ? F MET 485 
1175 1 Y 1 E GLN 468 ? F GLN 486 
1176 1 Y 1 E ILE 469 ? F ILE 487 
1177 1 Y 1 G MET -29 ? G MET 1   
1178 1 Y 1 G GLY -28 ? G GLY 2   
1179 1 Y 1 G SER -27 ? G SER 3   
1180 1 Y 1 G SER -26 ? G SER 4   
1181 1 Y 1 G HIS -25 ? G HIS 5   
1182 1 Y 1 G HIS -24 ? G HIS 6   
1183 1 Y 1 G HIS -23 ? G HIS 7   
1184 1 Y 1 G HIS -22 ? G HIS 8   
1185 1 Y 1 G HIS -21 ? G HIS 9   
1186 1 Y 1 G HIS -20 ? G HIS 10  
1187 1 Y 1 G HIS -19 ? G HIS 11  
1188 1 Y 1 G HIS -18 ? G HIS 12  
1189 1 Y 1 G HIS -17 ? G HIS 13  
1190 1 Y 1 G HIS -16 ? G HIS 14  
1191 1 Y 1 G MET -15 ? G MET 15  
1192 1 Y 1 G THR -14 ? G THR 16  
1193 1 Y 1 G ASP -13 ? G ASP 17  
1194 1 Y 1 G VAL -12 ? G VAL 18  
1195 1 Y 1 G THR -11 ? G THR 19  
1196 1 Y 1 G ILE -10 ? G ILE 20  
1197 1 Y 1 G LYS -9  ? G LYS 21  
1198 1 Y 1 G GLY -8  ? G GLY 22  
1199 1 Y 1 G GLY -7  ? G GLY 23  
1200 1 Y 1 G GLU -6  ? G GLU 24  
1201 1 Y 1 G ASN -5  ? G ASN 25  
1202 1 Y 1 G LEU -4  ? G LEU 26  
1203 1 Y 1 G TYR -3  ? G TYR 27  
1204 1 Y 1 G PHE -2  ? G PHE 28  
1205 1 Y 1 G GLN -1  ? G GLN 29  
1206 1 Y 1 G GLY 0   ? G GLY 30  
1207 1 Y 1 G MET 1   ? G MET 31  
1208 1 Y 1 G ALA 2   ? G ALA 32  
1209 1 Y 1 G ARG 3   ? G ARG 33  
1210 1 Y 1 G SER 4   ? G SER 34  
1211 1 Y 1 G PRO 5   ? G PRO 35  
1212 1 Y 1 G SER 6   ? G SER 36  
1213 1 Y 1 G LYS 7   ? G LYS 37  
1214 1 Y 1 G HIS 8   ? G HIS 38  
1215 1 Y 1 G GLY 9   ? G GLY 39  
1216 1 Y 1 G ARG 10  ? G ARG 40  
1217 1 Y 1 G ASP 11  ? G ASP 41  
1218 1 Y 1 G GLN 12  ? G GLN 42  
1219 1 Y 1 G THR 13  ? G THR 43  
1220 1 Y 1 G GLN 14  ? G GLN 44  
1221 1 Y 1 G ASP 15  ? G ASP 45  
1222 1 Y 1 G PHE 16  ? G PHE 46  
1223 1 Y 1 G GLN 17  ? G GLN 47  
1224 1 Y 1 G GLY 18  ? G GLY 48  
1225 1 Y 1 G PHE 19  ? G PHE 49  
1226 1 Y 1 G PHE 20  ? G PHE 50  
1227 1 Y 1 G ASN 21  ? G ASN 51  
1228 1 Y 1 G ASP 22  ? G ASP 52  
1229 1 Y 1 G LEU 23  ? G LEU 53  
1230 1 Y 1 G GLN 24  ? G GLN 54  
1231 1 Y 1 G ASP 25  ? G ASP 55  
1232 1 Y 1 G TRP 26  ? G TRP 56  
1233 1 Y 1 G GLU 27  ? G GLU 57  
1234 1 Y 1 G LEU 28  ? G LEU 58  
1235 1 Y 1 G SER 29  ? G SER 59  
1236 1 Y 1 G LEU 30  ? G LEU 60  
1237 1 Y 1 G LYS 31  ? G LYS 61  
1238 1 Y 1 G ASP 32  ? G ASP 62  
1239 1 Y 1 G LYS 33  ? G LYS 63  
1240 1 Y 1 G ASP 34  ? G ASP 64  
1241 1 Y 1 G LYS 35  ? G LYS 65  
1242 1 Y 1 G LYS 36  ? G LYS 66  
1243 1 Y 1 G ILE 37  ? G ILE 67  
1244 1 Y 1 G LYS 38  ? G LYS 68  
1245 1 Y 1 G GLN 39  ? G GLN 69  
1246 1 Y 1 G GLN 40  ? G GLN 70  
1247 1 Y 1 G PRO 41  ? G PRO 71  
1248 1 Y 1 G ALA 42  ? G ALA 72  
1249 1 Y 1 G ASN 43  ? G ASN 73  
1250 1 Y 1 G SER 44  ? G SER 74  
1251 1 Y 1 G SER 45  ? G SER 75  
1252 1 Y 1 G ASN 46  ? G ASN 76  
1253 1 Y 1 G PRO 47  ? G PRO 77  
1254 1 Y 1 G SER 48  ? G SER 78  
1255 1 Y 1 G SER 49  ? G SER 79  
1256 1 Y 1 G GLU 50  ? G GLU 80  
1257 1 Y 1 G THR 51  ? G THR 81  
1258 1 Y 1 G PHE 52  ? G PHE 82  
1259 1 Y 1 G ARG 53  ? G ARG 83  
1260 1 Y 1 G PRO 54  ? G PRO 84  
1261 1 Y 1 G SER 55  ? G SER 85  
1262 1 Y 1 G GLY 56  ? G GLY 86  
1263 1 Y 1 G SER 57  ? G SER 87  
1264 1 Y 1 G GLY 58  ? G GLY 88  
1265 1 Y 1 G LYS 59  ? G LYS 89  
1266 1 Y 1 G TYR 60  ? G TYR 90  
1267 1 Y 1 G ASP 61  ? G ASP 91  
1268 1 Y 1 G PHE 62  ? G PHE 92  
1269 1 Y 1 G ALA 63  ? G ALA 93  
1270 1 Y 1 G LYS 64  ? G LYS 94  
1271 1 Y 1 G LYS 65  ? G LYS 95  
1272 1 Y 1 G TYR 66  ? G TYR 96  
1273 1 Y 1 G ARG 67  ? G ARG 97  
1274 1 Y 1 G SER 68  ? G SER 98  
1275 1 Y 1 G ILE 69  ? G ILE 99  
1276 1 Y 1 G ARG 70  ? G ARG 100 
1277 1 Y 1 G ASP 71  ? G ASP 101 
1278 1 Y 1 G LEU 72  ? G LEU 102 
1279 1 Y 1 G SER 73  ? G SER 103 
1280 1 Y 1 G SER 74  ? G SER 104 
1281 1 Y 1 G SER 75  ? G SER 105 
1282 1 Y 1 G LEU 76  ? G LEU 106 
1283 1 Y 1 G ILE 77  ? G ILE 107 
1284 1 Y 1 G GLY 78  ? G GLY 108 
1285 1 Y 1 G GLU 79  ? G GLU 109 
1286 1 Y 1 G SER 80  ? G SER 110 
1287 1 Y 1 G LEU 81  ? G LEU 111 
1288 1 Y 1 G LEU 82  ? G LEU 112 
1289 1 Y 1 G ASP 83  ? G ASP 113 
1290 1 Y 1 G SER 84  ? G SER 114 
1291 1 Y 1 G SER 85  ? G SER 115 
1292 1 Y 1 G SER 86  ? G SER 116 
1293 1 Y 1 G GLU 87  ? G GLU 117 
1294 1 Y 1 G LYS 88  ? G LYS 118 
1295 1 Y 1 G GLU 89  ? G GLU 119 
1296 1 Y 1 G GLN 90  ? G GLN 120 
1297 1 Y 1 G GLY 91  ? G GLY 121 
1298 1 Y 1 G ASN 92  ? G ASN 122 
1299 1 Y 1 G GLU 93  ? G GLU 123 
1300 1 Y 1 G PHE 94  ? G PHE 124 
1301 1 Y 1 G PHE 95  ? G PHE 125 
1302 1 Y 1 G LYS 96  ? G LYS 126 
1303 1 Y 1 G GLN 97  ? G GLN 127 
1304 1 Y 1 G LYS 98  ? G LYS 128 
1305 1 Y 1 G LYS 99  ? G LYS 129 
1306 1 Y 1 G PHE 100 ? G PHE 130 
1307 1 Y 1 G ASN 101 ? G ASN 131 
1308 1 Y 1 G GLU 102 ? G GLU 132 
1309 1 Y 1 G ALA 103 ? G ALA 133 
1310 1 Y 1 G ILE 104 ? G ILE 134 
1311 1 Y 1 G ASP 105 ? G ASP 135 
1312 1 Y 1 G CYS 106 ? G CYS 136 
1313 1 Y 1 G TYR 107 ? G TYR 137 
1314 1 Y 1 G SER 108 ? G SER 138 
1315 1 Y 1 G ARG 109 ? G ARG 139 
1316 1 Y 1 G SER 110 ? G SER 140 
1317 1 Y 1 G ILE 111 ? G ILE 141 
1318 1 Y 1 G ALA 112 ? G ALA 142 
1319 1 Y 1 G LEU 113 ? G LEU 143 
1320 1 Y 1 G SER 114 ? G SER 144 
1321 1 Y 1 G PRO 115 ? G PRO 145 
1322 1 Y 1 G ASN 116 ? G ASN 146 
1323 1 Y 1 G ALA 117 ? G ALA 147 
1324 1 Y 1 G VAL 118 ? G VAL 148 
1325 1 Y 1 G THR 119 ? G THR 149 
1326 1 Y 1 G TYR 120 ? G TYR 150 
1327 1 Y 1 G ALA 121 ? G ALA 151 
1328 1 Y 1 G ASN 122 ? G ASN 152 
1329 1 Y 1 G ARG 123 ? G ARG 153 
1330 1 Y 1 G ALA 124 ? G ALA 154 
1331 1 Y 1 G MET 125 ? G MET 155 
1332 1 Y 1 G ALA 126 ? G ALA 156 
1333 1 Y 1 G TYR 127 ? G TYR 157 
1334 1 Y 1 G LEU 128 ? G LEU 158 
1335 1 Y 1 G LYS 129 ? G LYS 159 
1336 1 Y 1 G ILE 130 ? G ILE 160 
1337 1 Y 1 G LYS 131 ? G LYS 161 
1338 1 Y 1 G ARG 132 ? G ARG 162 
1339 1 Y 1 G TYR 133 ? G TYR 163 
1340 1 Y 1 G ARG 134 ? G ARG 164 
1341 1 Y 1 G GLU 135 ? G GLU 165 
1342 1 Y 1 G ALA 136 ? G ALA 166 
1343 1 Y 1 G GLU 137 ? G GLU 167 
1344 1 Y 1 G VAL 138 ? G VAL 168 
1345 1 Y 1 G ASP 139 ? G ASP 169 
1346 1 Y 1 G CYS 140 ? G CYS 170 
1347 1 Y 1 G THR 141 ? G THR 171 
1348 1 Y 1 G GLU 142 ? G GLU 172 
1349 1 Y 1 G ALA 143 ? G ALA 173 
1350 1 Y 1 G LEU 144 ? G LEU 174 
1351 1 Y 1 G ASN 145 ? G ASN 175 
1352 1 Y 1 G LEU 146 ? G LEU 176 
1353 1 Y 1 G ASP 147 ? G ASP 177 
1354 1 Y 1 G ASP 148 ? G ASP 178 
1355 1 Y 1 G ARG 149 ? G ARG 179 
1356 1 Y 1 G TYR 150 ? G TYR 180 
1357 1 Y 1 G ILE 151 ? G ILE 181 
1358 1 Y 1 G LYS 152 ? G LYS 182 
1359 1 Y 1 G ALA 153 ? G ALA 183 
1360 1 Y 1 G TYR 154 ? G TYR 184 
1361 1 Y 1 G SER 155 ? G SER 185 
1362 1 Y 1 G ARG 156 ? G ARG 186 
1363 1 Y 1 G ARG 157 ? G ARG 187 
1364 1 Y 1 G ALA 158 ? G ALA 188 
1365 1 Y 1 G THR 159 ? G THR 189 
1366 1 Y 1 G ALA 160 ? G ALA 190 
1367 1 Y 1 G ARG 161 ? G ARG 191 
1368 1 Y 1 G LYS 162 ? G LYS 192 
1369 1 Y 1 G GLU 163 ? G GLU 193 
1370 1 Y 1 G LEU 164 ? G LEU 194 
1371 1 Y 1 G GLY 165 ? G GLY 195 
1372 1 Y 1 G MET 166 ? G MET 196 
1373 1 Y 1 G ILE 167 ? G ILE 197 
1374 1 Y 1 G LYS 168 ? G LYS 198 
1375 1 Y 1 G GLU 169 ? G GLU 199 
1376 1 Y 1 G ALA 170 ? G ALA 200 
1377 1 Y 1 G LYS 171 ? G LYS 201 
1378 1 Y 1 G GLU 172 ? G GLU 202 
1379 1 Y 1 G ASP 173 ? G ASP 203 
1380 1 Y 1 G ALA 174 ? G ALA 204 
1381 1 Y 1 G GLU 175 ? G GLU 205 
1382 1 Y 1 G PHE 176 ? G PHE 206 
1383 1 Y 1 G ALA 177 ? G ALA 207 
1384 1 Y 1 G LEU 178 ? G LEU 208 
1385 1 Y 1 G ARG 179 ? G ARG 209 
1386 1 Y 1 G LEU 180 ? G LEU 210 
1387 1 Y 1 G GLU 181 ? G GLU 211 
1388 1 Y 1 G PRO 182 ? G PRO 212 
1389 1 Y 1 G GLU 183 ? G GLU 213 
1390 1 Y 1 G SER 184 ? G SER 214 
1391 1 Y 1 G GLN 185 ? G GLN 215 
1392 1 Y 1 G GLU 186 ? G GLU 216 
1393 1 Y 1 G LEU 187 ? G LEU 217 
1394 1 Y 1 G LYS 188 ? G LYS 218 
1395 1 Y 1 G LYS 189 ? G LYS 219 
1396 1 Y 1 G GLN 190 ? G GLN 220 
1397 1 Y 1 G TYR 191 ? G TYR 221 
1398 1 Y 1 G ALA 192 ? G ALA 222 
1399 1 Y 1 G ASP 193 ? G ASP 223 
1400 1 Y 1 G ILE 194 ? G ILE 224 
1401 1 Y 1 G LYS 195 ? G LYS 225 
1402 1 Y 1 G SER 196 ? G SER 226 
1403 1 Y 1 G LEU 197 ? G LEU 227 
1404 1 Y 1 G LEU 198 ? G LEU 228 
1405 1 Y 1 G GLU 199 ? G GLU 229 
1406 1 Y 1 G LYS 200 ? G LYS 230 
1407 1 Y 1 G GLU 201 ? G GLU 231 
1408 1 Y 1 G ILE 202 ? G ILE 232 
1409 1 Y 1 G ILE 203 ? G ILE 233 
1410 1 Y 1 G GLU 204 ? G GLU 234 
1411 1 Y 1 G LYS 205 ? G LYS 235 
1412 1 Y 1 G ALA 206 ? G ALA 236 
1413 1 Y 1 G THR 207 ? G THR 237 
1414 1 Y 1 G GLY 208 ? G GLY 238 
1415 1 Y 1 G ALA 209 ? G ALA 239 
1416 1 Y 1 G MET 210 ? G MET 240 
1417 1 Y 1 G GLN 211 ? G GLN 241 
1418 1 Y 1 G SER 212 ? G SER 242 
1419 1 Y 1 G THR 213 ? G THR 243 
1420 1 Y 1 G ALA 214 ? G ALA 244 
1421 1 Y 1 G GLN 215 ? G GLN 245 
1422 1 Y 1 G GLU 216 ? G GLU 246 
1423 1 Y 1 G LEU 217 ? G LEU 247 
1424 1 Y 1 G LEU 218 ? G LEU 248 
1425 1 Y 1 G LYS 219 ? G LYS 249 
1426 1 Y 1 G THR 220 ? G THR 250 
1427 1 Y 1 G SER 221 ? G SER 251 
1428 1 Y 1 G GLY 222 ? G GLY 252 
1429 1 Y 1 G LEU 223 ? G LEU 253 
1430 1 Y 1 G ASP 224 ? G ASP 254 
1431 1 Y 1 G LYS 225 ? G LYS 255 
1432 1 Y 1 G LYS 226 ? G LYS 256 
1433 1 Y 1 G ILE 227 ? G ILE 257 
1434 1 Y 1 G GLN 228 ? G GLN 258 
1435 1 Y 1 G LYS 229 ? G LYS 259 
1436 1 Y 1 G PRO 230 ? G PRO 260 
1437 1 Y 1 G LYS 231 ? G LYS 261 
1438 1 Y 1 G THR 232 ? G THR 262 
1439 1 Y 1 G GLU 233 ? G GLU 263 
1440 1 Y 1 G MET 234 ? G MET 264 
1441 1 Y 1 G THR 235 ? G THR 265 
1442 1 Y 1 G SER 236 ? G SER 266 
1443 1 Y 1 G LYS 237 ? G LYS 267 
1444 1 Y 1 G PRO 238 ? G PRO 268 
1445 1 Y 1 G VAL 239 ? G VAL 269 
1446 1 Y 1 G THR 240 ? G THR 270 
1447 1 Y 1 G LEU 241 ? G LEU 271 
1448 1 Y 1 G VAL 242 ? G VAL 272 
1449 1 Y 1 G ALA 243 ? G ALA 273 
1450 1 Y 1 G LYS 244 ? G LYS 274 
1451 1 Y 1 G THR 245 ? G THR 275 
1452 1 Y 1 G ASN 246 ? G ASN 276 
1453 1 Y 1 G ARG 247 ? G ARG 277 
1454 1 Y 1 G ASP 248 ? G ASP 278 
1455 1 Y 1 G ILE 249 ? G ILE 279 
1456 1 Y 1 G VAL 250 ? G VAL 280 
1457 1 Y 1 G GLN 251 ? G GLN 281 
1458 1 Y 1 G PRO 252 ? G PRO 282 
1459 1 Y 1 G VAL 253 ? G VAL 283 
1460 1 Y 1 G LEU 254 ? G LEU 284 
1461 1 Y 1 G GLY 255 ? G GLY 285 
1462 1 Y 1 G SER 256 ? G SER 286 
1463 1 Y 1 G ASN 257 ? G ASN 287 
1464 1 Y 1 G GLU 258 ? G GLU 288 
1465 1 Y 1 G SER 259 ? G SER 289 
1466 1 Y 1 G SER 260 ? G SER 290 
1467 1 Y 1 G GLY 261 ? G GLY 291 
1468 1 Y 1 G LYS 262 ? G LYS 292 
1469 1 Y 1 G LYS 263 ? G LYS 293 
1470 1 Y 1 G LEU 264 ? G LEU 294 
1471 1 Y 1 G ILE 265 ? G ILE 295 
1472 1 Y 1 G GLU 266 ? G GLU 296 
1473 1 Y 1 G ASN 267 ? G ASN 297 
1474 1 Y 1 G ILE 268 ? G ILE 298 
1475 1 Y 1 G GLN 269 ? G GLN 299 
1476 1 Y 1 G PRO 270 ? G PRO 300 
1477 1 Y 1 G GLU 271 ? G GLU 301 
1478 1 Y 1 G GLU 272 ? G GLU 302 
1479 1 Y 1 G LYS 273 ? G LYS 303 
1480 1 Y 1 G SER 274 ? G SER 304 
1481 1 Y 1 G LYS 275 ? G LYS 305 
1482 1 Y 1 G GLU 276 ? G GLU 306 
1483 1 Y 1 G GLY 277 ? G GLY 307 
1484 1 Y 1 G SER 278 ? G SER 308 
1485 1 Y 1 G MET 279 ? G MET 309 
1486 1 Y 1 G LYS 280 ? G LYS 310 
1487 1 Y 1 G ILE 281 ? G ILE 311 
1488 1 Y 1 G PRO 282 ? G PRO 312 
1489 1 Y 1 G ALA 283 ? G ALA 313 
1490 1 Y 1 G ILE 284 ? G ILE 314 
1491 1 Y 1 G THR 285 ? G THR 315 
1492 1 Y 1 G GLU 286 ? G GLU 316 
1493 1 Y 1 G ILE 287 ? G ILE 317 
1494 1 Y 1 G LEU 288 ? G LEU 318 
1495 1 Y 1 G ASP 289 ? G ASP 319 
1496 1 Y 1 G SER 290 ? G SER 320 
1497 1 Y 1 G LYS 291 ? G LYS 321 
1498 1 Y 1 G LYS 292 ? G LYS 322 
1499 1 Y 1 G VAL 293 ? G VAL 323 
1500 1 Y 1 G THR 294 ? G THR 324 
1501 1 Y 1 G PRO 295 ? G PRO 325 
1502 1 Y 1 G GLY 296 ? G GLY 326 
1503 1 Y 1 G SER 297 ? G SER 327 
1504 1 Y 1 G GLN 298 ? G GLN 328 
1505 1 Y 1 G SER 299 ? G SER 329 
1506 1 Y 1 G TYR 300 ? G TYR 330 
1507 1 Y 1 G GLU 301 ? G GLU 331 
1508 1 Y 1 G LYS 302 ? G LYS 332 
1509 1 Y 1 G GLU 303 ? G GLU 333 
1510 1 Y 1 G ALA 304 ? G ALA 334 
1511 1 Y 1 G LYS 305 ? G LYS 335 
1512 1 Y 1 G PRO 306 ? G PRO 336 
1513 1 Y 1 G SER 307 ? G SER 337 
1514 1 Y 1 G ASP 308 ? G ASP 338 
1515 1 Y 1 G ARG 309 ? G ARG 339 
1516 1 Y 1 G ASN 310 ? G ASN 340 
1517 1 Y 1 G GLY 311 ? G GLY 341 
1518 1 Y 1 G THR 312 ? G THR 342 
1519 1 Y 1 G GLN 313 ? G GLN 343 
1520 1 Y 1 G PRO 314 ? G PRO 344 
1521 1 Y 1 G SER 315 ? G SER 345 
1522 1 Y 1 G GLY 316 ? G GLY 346 
1523 1 Y 1 G PRO 317 ? G PRO 347 
1524 1 Y 1 G GLU 318 ? G GLU 348 
1525 1 Y 1 G ASN 319 ? G ASN 349 
1526 1 Y 1 G GLN 320 ? G GLN 350 
1527 1 Y 1 G VAL 321 ? G VAL 351 
1528 1 Y 1 G SER 322 ? G SER 352 
1529 1 Y 1 G LYS 323 ? G LYS 353 
1530 1 Y 1 G GLN 324 ? G GLN 354 
1531 1 Y 1 G LEU 325 ? G LEU 355 
1532 1 Y 1 G GLU 326 ? G GLU 356 
1533 1 Y 1 G LEU 327 ? G LEU 357 
1534 1 Y 1 G LYS 328 ? G LYS 358 
1535 1 Y 1 G PRO 329 ? G PRO 359 
1536 1 Y 1 G SER 330 ? G SER 360 
1537 1 Y 1 G VAL 331 ? G VAL 361 
1538 1 Y 1 G GLN 332 ? G GLN 362 
1539 1 Y 1 G GLU 333 ? G GLU 363 
1540 1 Y 1 G LEU 334 ? G LEU 364 
1541 1 Y 1 G ALA 335 ? G ALA 365 
1542 1 Y 1 G ALA 336 ? G ALA 366 
1543 1 Y 1 G HIS 337 ? G HIS 367 
1544 1 Y 1 G ALA 338 ? G ALA 368 
1545 1 Y 1 G ALA 339 ? G ALA 369 
1546 1 Y 1 G SER 340 ? G SER 370 
1547 1 Y 1 G LEU 341 ? G LEU 371 
1548 1 Y 1 G ALA 342 ? G ALA 372 
1549 1 Y 1 G MET 343 ? G MET 373 
1550 1 Y 1 G THR 344 ? G THR 374 
1551 1 Y 1 G GLU 345 ? G GLU 375 
1552 1 Y 1 G ALA 346 ? G ALA 376 
1553 1 Y 1 G LEU 477 ? G LEU 507 
1554 1 Y 1 G GLU 478 ? G GLU 508 
1555 1 Y 1 G VAL 479 ? G VAL 509 
1556 1 Y 1 G LEU 480 ? G LEU 510 
1557 1 Y 1 G PHE 481 ? G PHE 511 
1558 1 Y 1 G GLN 482 ? G GLN 512 
1559 1 Y 1 G GLY 483 ? G GLY 513 
1560 1 Y 1 G PRO 484 ? G PRO 514 
1561 1 Y 1 G TRP 485 ? G TRP 515 
1562 1 Y 1 G SER 486 ? G SER 516 
1563 1 Y 1 G HIS 487 ? G HIS 517 
1564 1 Y 1 G PRO 488 ? G PRO 518 
1565 1 Y 1 G GLN 489 ? G GLN 519 
1566 1 Y 1 G PHE 490 ? G PHE 520 
1567 1 Y 1 G GLU 491 ? G GLU 521 
1568 1 Y 1 G LYS 492 ? G LYS 522 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ADP PB     P N N 1   
ADP O1B    O N N 2   
ADP O2B    O N N 3   
ADP O3B    O N N 4   
ADP PA     P N S 5   
ADP O1A    O N N 6   
ADP O2A    O N N 7   
ADP O3A    O N N 8   
ADP "O5'"  O N N 9   
ADP "C5'"  C N N 10  
ADP "C4'"  C N R 11  
ADP "O4'"  O N N 12  
ADP "C3'"  C N S 13  
ADP "O3'"  O N N 14  
ADP "C2'"  C N R 15  
ADP "O2'"  O N N 16  
ADP "C1'"  C N R 17  
ADP N9     N Y N 18  
ADP C8     C Y N 19  
ADP N7     N Y N 20  
ADP C5     C Y N 21  
ADP C6     C Y N 22  
ADP N6     N N N 23  
ADP N1     N Y N 24  
ADP C2     C Y N 25  
ADP N3     N Y N 26  
ADP C4     C Y N 27  
ADP HOB2   H N N 28  
ADP HOB3   H N N 29  
ADP HOA2   H N N 30  
ADP "H5'1" H N N 31  
ADP "H5'2" H N N 32  
ADP "H4'"  H N N 33  
ADP "H3'"  H N N 34  
ADP "HO3'" H N N 35  
ADP "H2'"  H N N 36  
ADP "HO2'" H N N 37  
ADP "H1'"  H N N 38  
ADP H8     H N N 39  
ADP HN61   H N N 40  
ADP HN62   H N N 41  
ADP H2     H N N 42  
ALA N      N N N 43  
ALA CA     C N S 44  
ALA C      C N N 45  
ALA O      O N N 46  
ALA CB     C N N 47  
ALA OXT    O N N 48  
ALA H      H N N 49  
ALA H2     H N N 50  
ALA HA     H N N 51  
ALA HB1    H N N 52  
ALA HB2    H N N 53  
ALA HB3    H N N 54  
ALA HXT    H N N 55  
ARG N      N N N 56  
ARG CA     C N S 57  
ARG C      C N N 58  
ARG O      O N N 59  
ARG CB     C N N 60  
ARG CG     C N N 61  
ARG CD     C N N 62  
ARG NE     N N N 63  
ARG CZ     C N N 64  
ARG NH1    N N N 65  
ARG NH2    N N N 66  
ARG OXT    O N N 67  
ARG H      H N N 68  
ARG H2     H N N 69  
ARG HA     H N N 70  
ARG HB2    H N N 71  
ARG HB3    H N N 72  
ARG HG2    H N N 73  
ARG HG3    H N N 74  
ARG HD2    H N N 75  
ARG HD3    H N N 76  
ARG HE     H N N 77  
ARG HH11   H N N 78  
ARG HH12   H N N 79  
ARG HH21   H N N 80  
ARG HH22   H N N 81  
ARG HXT    H N N 82  
ASN N      N N N 83  
ASN CA     C N S 84  
ASN C      C N N 85  
ASN O      O N N 86  
ASN CB     C N N 87  
ASN CG     C N N 88  
ASN OD1    O N N 89  
ASN ND2    N N N 90  
ASN OXT    O N N 91  
ASN H      H N N 92  
ASN H2     H N N 93  
ASN HA     H N N 94  
ASN HB2    H N N 95  
ASN HB3    H N N 96  
ASN HD21   H N N 97  
ASN HD22   H N N 98  
ASN HXT    H N N 99  
ASP N      N N N 100 
ASP CA     C N S 101 
ASP C      C N N 102 
ASP O      O N N 103 
ASP CB     C N N 104 
ASP CG     C N N 105 
ASP OD1    O N N 106 
ASP OD2    O N N 107 
ASP OXT    O N N 108 
ASP H      H N N 109 
ASP H2     H N N 110 
ASP HA     H N N 111 
ASP HB2    H N N 112 
ASP HB3    H N N 113 
ASP HD2    H N N 114 
ASP HXT    H N N 115 
CYS N      N N N 116 
CYS CA     C N R 117 
CYS C      C N N 118 
CYS O      O N N 119 
CYS CB     C N N 120 
CYS SG     S N N 121 
CYS OXT    O N N 122 
CYS H      H N N 123 
CYS H2     H N N 124 
CYS HA     H N N 125 
CYS HB2    H N N 126 
CYS HB3    H N N 127 
CYS HG     H N N 128 
CYS HXT    H N N 129 
GLN N      N N N 130 
GLN CA     C N S 131 
GLN C      C N N 132 
GLN O      O N N 133 
GLN CB     C N N 134 
GLN CG     C N N 135 
GLN CD     C N N 136 
GLN OE1    O N N 137 
GLN NE2    N N N 138 
GLN OXT    O N N 139 
GLN H      H N N 140 
GLN H2     H N N 141 
GLN HA     H N N 142 
GLN HB2    H N N 143 
GLN HB3    H N N 144 
GLN HG2    H N N 145 
GLN HG3    H N N 146 
GLN HE21   H N N 147 
GLN HE22   H N N 148 
GLN HXT    H N N 149 
GLU N      N N N 150 
GLU CA     C N S 151 
GLU C      C N N 152 
GLU O      O N N 153 
GLU CB     C N N 154 
GLU CG     C N N 155 
GLU CD     C N N 156 
GLU OE1    O N N 157 
GLU OE2    O N N 158 
GLU OXT    O N N 159 
GLU H      H N N 160 
GLU H2     H N N 161 
GLU HA     H N N 162 
GLU HB2    H N N 163 
GLU HB3    H N N 164 
GLU HG2    H N N 165 
GLU HG3    H N N 166 
GLU HE2    H N N 167 
GLU HXT    H N N 168 
GLY N      N N N 169 
GLY CA     C N N 170 
GLY C      C N N 171 
GLY O      O N N 172 
GLY OXT    O N N 173 
GLY H      H N N 174 
GLY H2     H N N 175 
GLY HA2    H N N 176 
GLY HA3    H N N 177 
GLY HXT    H N N 178 
HIS N      N N N 179 
HIS CA     C N S 180 
HIS C      C N N 181 
HIS O      O N N 182 
HIS CB     C N N 183 
HIS CG     C Y N 184 
HIS ND1    N Y N 185 
HIS CD2    C Y N 186 
HIS CE1    C Y N 187 
HIS NE2    N Y N 188 
HIS OXT    O N N 189 
HIS H      H N N 190 
HIS H2     H N N 191 
HIS HA     H N N 192 
HIS HB2    H N N 193 
HIS HB3    H N N 194 
HIS HD1    H N N 195 
HIS HD2    H N N 196 
HIS HE1    H N N 197 
HIS HE2    H N N 198 
HIS HXT    H N N 199 
ILE N      N N N 200 
ILE CA     C N S 201 
ILE C      C N N 202 
ILE O      O N N 203 
ILE CB     C N S 204 
ILE CG1    C N N 205 
ILE CG2    C N N 206 
ILE CD1    C N N 207 
ILE OXT    O N N 208 
ILE H      H N N 209 
ILE H2     H N N 210 
ILE HA     H N N 211 
ILE HB     H N N 212 
ILE HG12   H N N 213 
ILE HG13   H N N 214 
ILE HG21   H N N 215 
ILE HG22   H N N 216 
ILE HG23   H N N 217 
ILE HD11   H N N 218 
ILE HD12   H N N 219 
ILE HD13   H N N 220 
ILE HXT    H N N 221 
LEU N      N N N 222 
LEU CA     C N S 223 
LEU C      C N N 224 
LEU O      O N N 225 
LEU CB     C N N 226 
LEU CG     C N N 227 
LEU CD1    C N N 228 
LEU CD2    C N N 229 
LEU OXT    O N N 230 
LEU H      H N N 231 
LEU H2     H N N 232 
LEU HA     H N N 233 
LEU HB2    H N N 234 
LEU HB3    H N N 235 
LEU HG     H N N 236 
LEU HD11   H N N 237 
LEU HD12   H N N 238 
LEU HD13   H N N 239 
LEU HD21   H N N 240 
LEU HD22   H N N 241 
LEU HD23   H N N 242 
LEU HXT    H N N 243 
LYS N      N N N 244 
LYS CA     C N S 245 
LYS C      C N N 246 
LYS O      O N N 247 
LYS CB     C N N 248 
LYS CG     C N N 249 
LYS CD     C N N 250 
LYS CE     C N N 251 
LYS NZ     N N N 252 
LYS OXT    O N N 253 
LYS H      H N N 254 
LYS H2     H N N 255 
LYS HA     H N N 256 
LYS HB2    H N N 257 
LYS HB3    H N N 258 
LYS HG2    H N N 259 
LYS HG3    H N N 260 
LYS HD2    H N N 261 
LYS HD3    H N N 262 
LYS HE2    H N N 263 
LYS HE3    H N N 264 
LYS HZ1    H N N 265 
LYS HZ2    H N N 266 
LYS HZ3    H N N 267 
LYS HXT    H N N 268 
MET N      N N N 269 
MET CA     C N S 270 
MET C      C N N 271 
MET O      O N N 272 
MET CB     C N N 273 
MET CG     C N N 274 
MET SD     S N N 275 
MET CE     C N N 276 
MET OXT    O N N 277 
MET H      H N N 278 
MET H2     H N N 279 
MET HA     H N N 280 
MET HB2    H N N 281 
MET HB3    H N N 282 
MET HG2    H N N 283 
MET HG3    H N N 284 
MET HE1    H N N 285 
MET HE2    H N N 286 
MET HE3    H N N 287 
MET HXT    H N N 288 
PHE N      N N N 289 
PHE CA     C N S 290 
PHE C      C N N 291 
PHE O      O N N 292 
PHE CB     C N N 293 
PHE CG     C Y N 294 
PHE CD1    C Y N 295 
PHE CD2    C Y N 296 
PHE CE1    C Y N 297 
PHE CE2    C Y N 298 
PHE CZ     C Y N 299 
PHE OXT    O N N 300 
PHE H      H N N 301 
PHE H2     H N N 302 
PHE HA     H N N 303 
PHE HB2    H N N 304 
PHE HB3    H N N 305 
PHE HD1    H N N 306 
PHE HD2    H N N 307 
PHE HE1    H N N 308 
PHE HE2    H N N 309 
PHE HZ     H N N 310 
PHE HXT    H N N 311 
PRO N      N N N 312 
PRO CA     C N S 313 
PRO C      C N N 314 
PRO O      O N N 315 
PRO CB     C N N 316 
PRO CG     C N N 317 
PRO CD     C N N 318 
PRO OXT    O N N 319 
PRO H      H N N 320 
PRO HA     H N N 321 
PRO HB2    H N N 322 
PRO HB3    H N N 323 
PRO HG2    H N N 324 
PRO HG3    H N N 325 
PRO HD2    H N N 326 
PRO HD3    H N N 327 
PRO HXT    H N N 328 
SER N      N N N 329 
SER CA     C N S 330 
SER C      C N N 331 
SER O      O N N 332 
SER CB     C N N 333 
SER OG     O N N 334 
SER OXT    O N N 335 
SER H      H N N 336 
SER H2     H N N 337 
SER HA     H N N 338 
SER HB2    H N N 339 
SER HB3    H N N 340 
SER HG     H N N 341 
SER HXT    H N N 342 
THR N      N N N 343 
THR CA     C N S 344 
THR C      C N N 345 
THR O      O N N 346 
THR CB     C N R 347 
THR OG1    O N N 348 
THR CG2    C N N 349 
THR OXT    O N N 350 
THR H      H N N 351 
THR H2     H N N 352 
THR HA     H N N 353 
THR HB     H N N 354 
THR HG1    H N N 355 
THR HG21   H N N 356 
THR HG22   H N N 357 
THR HG23   H N N 358 
THR HXT    H N N 359 
TRP N      N N N 360 
TRP CA     C N S 361 
TRP C      C N N 362 
TRP O      O N N 363 
TRP CB     C N N 364 
TRP CG     C Y N 365 
TRP CD1    C Y N 366 
TRP CD2    C Y N 367 
TRP NE1    N Y N 368 
TRP CE2    C Y N 369 
TRP CE3    C Y N 370 
TRP CZ2    C Y N 371 
TRP CZ3    C Y N 372 
TRP CH2    C Y N 373 
TRP OXT    O N N 374 
TRP H      H N N 375 
TRP H2     H N N 376 
TRP HA     H N N 377 
TRP HB2    H N N 378 
TRP HB3    H N N 379 
TRP HD1    H N N 380 
TRP HE1    H N N 381 
TRP HE3    H N N 382 
TRP HZ2    H N N 383 
TRP HZ3    H N N 384 
TRP HH2    H N N 385 
TRP HXT    H N N 386 
TYR N      N N N 387 
TYR CA     C N S 388 
TYR C      C N N 389 
TYR O      O N N 390 
TYR CB     C N N 391 
TYR CG     C Y N 392 
TYR CD1    C Y N 393 
TYR CD2    C Y N 394 
TYR CE1    C Y N 395 
TYR CE2    C Y N 396 
TYR CZ     C Y N 397 
TYR OH     O N N 398 
TYR OXT    O N N 399 
TYR H      H N N 400 
TYR H2     H N N 401 
TYR HA     H N N 402 
TYR HB2    H N N 403 
TYR HB3    H N N 404 
TYR HD1    H N N 405 
TYR HD2    H N N 406 
TYR HE1    H N N 407 
TYR HE2    H N N 408 
TYR HH     H N N 409 
TYR HXT    H N N 410 
VAL N      N N N 411 
VAL CA     C N S 412 
VAL C      C N N 413 
VAL O      O N N 414 
VAL CB     C N N 415 
VAL CG1    C N N 416 
VAL CG2    C N N 417 
VAL OXT    O N N 418 
VAL H      H N N 419 
VAL H2     H N N 420 
VAL HA     H N N 421 
VAL HB     H N N 422 
VAL HG11   H N N 423 
VAL HG12   H N N 424 
VAL HG13   H N N 425 
VAL HG21   H N N 426 
VAL HG22   H N N 427 
VAL HG23   H N N 428 
VAL HXT    H N N 429 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ADP PB    O1B    doub N N 1   
ADP PB    O2B    sing N N 2   
ADP PB    O3B    sing N N 3   
ADP PB    O3A    sing N N 4   
ADP O2B   HOB2   sing N N 5   
ADP O3B   HOB3   sing N N 6   
ADP PA    O1A    doub N N 7   
ADP PA    O2A    sing N N 8   
ADP PA    O3A    sing N N 9   
ADP PA    "O5'"  sing N N 10  
ADP O2A   HOA2   sing N N 11  
ADP "O5'" "C5'"  sing N N 12  
ADP "C5'" "C4'"  sing N N 13  
ADP "C5'" "H5'1" sing N N 14  
ADP "C5'" "H5'2" sing N N 15  
ADP "C4'" "O4'"  sing N N 16  
ADP "C4'" "C3'"  sing N N 17  
ADP "C4'" "H4'"  sing N N 18  
ADP "O4'" "C1'"  sing N N 19  
ADP "C3'" "O3'"  sing N N 20  
ADP "C3'" "C2'"  sing N N 21  
ADP "C3'" "H3'"  sing N N 22  
ADP "O3'" "HO3'" sing N N 23  
ADP "C2'" "O2'"  sing N N 24  
ADP "C2'" "C1'"  sing N N 25  
ADP "C2'" "H2'"  sing N N 26  
ADP "O2'" "HO2'" sing N N 27  
ADP "C1'" N9     sing N N 28  
ADP "C1'" "H1'"  sing N N 29  
ADP N9    C8     sing Y N 30  
ADP N9    C4     sing Y N 31  
ADP C8    N7     doub Y N 32  
ADP C8    H8     sing N N 33  
ADP N7    C5     sing Y N 34  
ADP C5    C6     sing Y N 35  
ADP C5    C4     doub Y N 36  
ADP C6    N6     sing N N 37  
ADP C6    N1     doub Y N 38  
ADP N6    HN61   sing N N 39  
ADP N6    HN62   sing N N 40  
ADP N1    C2     sing Y N 41  
ADP C2    N3     doub Y N 42  
ADP C2    H2     sing N N 43  
ADP N3    C4     sing Y N 44  
ALA N     CA     sing N N 45  
ALA N     H      sing N N 46  
ALA N     H2     sing N N 47  
ALA CA    C      sing N N 48  
ALA CA    CB     sing N N 49  
ALA CA    HA     sing N N 50  
ALA C     O      doub N N 51  
ALA C     OXT    sing N N 52  
ALA CB    HB1    sing N N 53  
ALA CB    HB2    sing N N 54  
ALA CB    HB3    sing N N 55  
ALA OXT   HXT    sing N N 56  
ARG N     CA     sing N N 57  
ARG N     H      sing N N 58  
ARG N     H2     sing N N 59  
ARG CA    C      sing N N 60  
ARG CA    CB     sing N N 61  
ARG CA    HA     sing N N 62  
ARG C     O      doub N N 63  
ARG C     OXT    sing N N 64  
ARG CB    CG     sing N N 65  
ARG CB    HB2    sing N N 66  
ARG CB    HB3    sing N N 67  
ARG CG    CD     sing N N 68  
ARG CG    HG2    sing N N 69  
ARG CG    HG3    sing N N 70  
ARG CD    NE     sing N N 71  
ARG CD    HD2    sing N N 72  
ARG CD    HD3    sing N N 73  
ARG NE    CZ     sing N N 74  
ARG NE    HE     sing N N 75  
ARG CZ    NH1    sing N N 76  
ARG CZ    NH2    doub N N 77  
ARG NH1   HH11   sing N N 78  
ARG NH1   HH12   sing N N 79  
ARG NH2   HH21   sing N N 80  
ARG NH2   HH22   sing N N 81  
ARG OXT   HXT    sing N N 82  
ASN N     CA     sing N N 83  
ASN N     H      sing N N 84  
ASN N     H2     sing N N 85  
ASN CA    C      sing N N 86  
ASN CA    CB     sing N N 87  
ASN CA    HA     sing N N 88  
ASN C     O      doub N N 89  
ASN C     OXT    sing N N 90  
ASN CB    CG     sing N N 91  
ASN CB    HB2    sing N N 92  
ASN CB    HB3    sing N N 93  
ASN CG    OD1    doub N N 94  
ASN CG    ND2    sing N N 95  
ASN ND2   HD21   sing N N 96  
ASN ND2   HD22   sing N N 97  
ASN OXT   HXT    sing N N 98  
ASP N     CA     sing N N 99  
ASP N     H      sing N N 100 
ASP N     H2     sing N N 101 
ASP CA    C      sing N N 102 
ASP CA    CB     sing N N 103 
ASP CA    HA     sing N N 104 
ASP C     O      doub N N 105 
ASP C     OXT    sing N N 106 
ASP CB    CG     sing N N 107 
ASP CB    HB2    sing N N 108 
ASP CB    HB3    sing N N 109 
ASP CG    OD1    doub N N 110 
ASP CG    OD2    sing N N 111 
ASP OD2   HD2    sing N N 112 
ASP OXT   HXT    sing N N 113 
CYS N     CA     sing N N 114 
CYS N     H      sing N N 115 
CYS N     H2     sing N N 116 
CYS CA    C      sing N N 117 
CYS CA    CB     sing N N 118 
CYS CA    HA     sing N N 119 
CYS C     O      doub N N 120 
CYS C     OXT    sing N N 121 
CYS CB    SG     sing N N 122 
CYS CB    HB2    sing N N 123 
CYS CB    HB3    sing N N 124 
CYS SG    HG     sing N N 125 
CYS OXT   HXT    sing N N 126 
GLN N     CA     sing N N 127 
GLN N     H      sing N N 128 
GLN N     H2     sing N N 129 
GLN CA    C      sing N N 130 
GLN CA    CB     sing N N 131 
GLN CA    HA     sing N N 132 
GLN C     O      doub N N 133 
GLN C     OXT    sing N N 134 
GLN CB    CG     sing N N 135 
GLN CB    HB2    sing N N 136 
GLN CB    HB3    sing N N 137 
GLN CG    CD     sing N N 138 
GLN CG    HG2    sing N N 139 
GLN CG    HG3    sing N N 140 
GLN CD    OE1    doub N N 141 
GLN CD    NE2    sing N N 142 
GLN NE2   HE21   sing N N 143 
GLN NE2   HE22   sing N N 144 
GLN OXT   HXT    sing N N 145 
GLU N     CA     sing N N 146 
GLU N     H      sing N N 147 
GLU N     H2     sing N N 148 
GLU CA    C      sing N N 149 
GLU CA    CB     sing N N 150 
GLU CA    HA     sing N N 151 
GLU C     O      doub N N 152 
GLU C     OXT    sing N N 153 
GLU CB    CG     sing N N 154 
GLU CB    HB2    sing N N 155 
GLU CB    HB3    sing N N 156 
GLU CG    CD     sing N N 157 
GLU CG    HG2    sing N N 158 
GLU CG    HG3    sing N N 159 
GLU CD    OE1    doub N N 160 
GLU CD    OE2    sing N N 161 
GLU OE2   HE2    sing N N 162 
GLU OXT   HXT    sing N N 163 
GLY N     CA     sing N N 164 
GLY N     H      sing N N 165 
GLY N     H2     sing N N 166 
GLY CA    C      sing N N 167 
GLY CA    HA2    sing N N 168 
GLY CA    HA3    sing N N 169 
GLY C     O      doub N N 170 
GLY C     OXT    sing N N 171 
GLY OXT   HXT    sing N N 172 
HIS N     CA     sing N N 173 
HIS N     H      sing N N 174 
HIS N     H2     sing N N 175 
HIS CA    C      sing N N 176 
HIS CA    CB     sing N N 177 
HIS CA    HA     sing N N 178 
HIS C     O      doub N N 179 
HIS C     OXT    sing N N 180 
HIS CB    CG     sing N N 181 
HIS CB    HB2    sing N N 182 
HIS CB    HB3    sing N N 183 
HIS CG    ND1    sing Y N 184 
HIS CG    CD2    doub Y N 185 
HIS ND1   CE1    doub Y N 186 
HIS ND1   HD1    sing N N 187 
HIS CD2   NE2    sing Y N 188 
HIS CD2   HD2    sing N N 189 
HIS CE1   NE2    sing Y N 190 
HIS CE1   HE1    sing N N 191 
HIS NE2   HE2    sing N N 192 
HIS OXT   HXT    sing N N 193 
ILE N     CA     sing N N 194 
ILE N     H      sing N N 195 
ILE N     H2     sing N N 196 
ILE CA    C      sing N N 197 
ILE CA    CB     sing N N 198 
ILE CA    HA     sing N N 199 
ILE C     O      doub N N 200 
ILE C     OXT    sing N N 201 
ILE CB    CG1    sing N N 202 
ILE CB    CG2    sing N N 203 
ILE CB    HB     sing N N 204 
ILE CG1   CD1    sing N N 205 
ILE CG1   HG12   sing N N 206 
ILE CG1   HG13   sing N N 207 
ILE CG2   HG21   sing N N 208 
ILE CG2   HG22   sing N N 209 
ILE CG2   HG23   sing N N 210 
ILE CD1   HD11   sing N N 211 
ILE CD1   HD12   sing N N 212 
ILE CD1   HD13   sing N N 213 
ILE OXT   HXT    sing N N 214 
LEU N     CA     sing N N 215 
LEU N     H      sing N N 216 
LEU N     H2     sing N N 217 
LEU CA    C      sing N N 218 
LEU CA    CB     sing N N 219 
LEU CA    HA     sing N N 220 
LEU C     O      doub N N 221 
LEU C     OXT    sing N N 222 
LEU CB    CG     sing N N 223 
LEU CB    HB2    sing N N 224 
LEU CB    HB3    sing N N 225 
LEU CG    CD1    sing N N 226 
LEU CG    CD2    sing N N 227 
LEU CG    HG     sing N N 228 
LEU CD1   HD11   sing N N 229 
LEU CD1   HD12   sing N N 230 
LEU CD1   HD13   sing N N 231 
LEU CD2   HD21   sing N N 232 
LEU CD2   HD22   sing N N 233 
LEU CD2   HD23   sing N N 234 
LEU OXT   HXT    sing N N 235 
LYS N     CA     sing N N 236 
LYS N     H      sing N N 237 
LYS N     H2     sing N N 238 
LYS CA    C      sing N N 239 
LYS CA    CB     sing N N 240 
LYS CA    HA     sing N N 241 
LYS C     O      doub N N 242 
LYS C     OXT    sing N N 243 
LYS CB    CG     sing N N 244 
LYS CB    HB2    sing N N 245 
LYS CB    HB3    sing N N 246 
LYS CG    CD     sing N N 247 
LYS CG    HG2    sing N N 248 
LYS CG    HG3    sing N N 249 
LYS CD    CE     sing N N 250 
LYS CD    HD2    sing N N 251 
LYS CD    HD3    sing N N 252 
LYS CE    NZ     sing N N 253 
LYS CE    HE2    sing N N 254 
LYS CE    HE3    sing N N 255 
LYS NZ    HZ1    sing N N 256 
LYS NZ    HZ2    sing N N 257 
LYS NZ    HZ3    sing N N 258 
LYS OXT   HXT    sing N N 259 
MET N     CA     sing N N 260 
MET N     H      sing N N 261 
MET N     H2     sing N N 262 
MET CA    C      sing N N 263 
MET CA    CB     sing N N 264 
MET CA    HA     sing N N 265 
MET C     O      doub N N 266 
MET C     OXT    sing N N 267 
MET CB    CG     sing N N 268 
MET CB    HB2    sing N N 269 
MET CB    HB3    sing N N 270 
MET CG    SD     sing N N 271 
MET CG    HG2    sing N N 272 
MET CG    HG3    sing N N 273 
MET SD    CE     sing N N 274 
MET CE    HE1    sing N N 275 
MET CE    HE2    sing N N 276 
MET CE    HE3    sing N N 277 
MET OXT   HXT    sing N N 278 
PHE N     CA     sing N N 279 
PHE N     H      sing N N 280 
PHE N     H2     sing N N 281 
PHE CA    C      sing N N 282 
PHE CA    CB     sing N N 283 
PHE CA    HA     sing N N 284 
PHE C     O      doub N N 285 
PHE C     OXT    sing N N 286 
PHE CB    CG     sing N N 287 
PHE CB    HB2    sing N N 288 
PHE CB    HB3    sing N N 289 
PHE CG    CD1    doub Y N 290 
PHE CG    CD2    sing Y N 291 
PHE CD1   CE1    sing Y N 292 
PHE CD1   HD1    sing N N 293 
PHE CD2   CE2    doub Y N 294 
PHE CD2   HD2    sing N N 295 
PHE CE1   CZ     doub Y N 296 
PHE CE1   HE1    sing N N 297 
PHE CE2   CZ     sing Y N 298 
PHE CE2   HE2    sing N N 299 
PHE CZ    HZ     sing N N 300 
PHE OXT   HXT    sing N N 301 
PRO N     CA     sing N N 302 
PRO N     CD     sing N N 303 
PRO N     H      sing N N 304 
PRO CA    C      sing N N 305 
PRO CA    CB     sing N N 306 
PRO CA    HA     sing N N 307 
PRO C     O      doub N N 308 
PRO C     OXT    sing N N 309 
PRO CB    CG     sing N N 310 
PRO CB    HB2    sing N N 311 
PRO CB    HB3    sing N N 312 
PRO CG    CD     sing N N 313 
PRO CG    HG2    sing N N 314 
PRO CG    HG3    sing N N 315 
PRO CD    HD2    sing N N 316 
PRO CD    HD3    sing N N 317 
PRO OXT   HXT    sing N N 318 
SER N     CA     sing N N 319 
SER N     H      sing N N 320 
SER N     H2     sing N N 321 
SER CA    C      sing N N 322 
SER CA    CB     sing N N 323 
SER CA    HA     sing N N 324 
SER C     O      doub N N 325 
SER C     OXT    sing N N 326 
SER CB    OG     sing N N 327 
SER CB    HB2    sing N N 328 
SER CB    HB3    sing N N 329 
SER OG    HG     sing N N 330 
SER OXT   HXT    sing N N 331 
THR N     CA     sing N N 332 
THR N     H      sing N N 333 
THR N     H2     sing N N 334 
THR CA    C      sing N N 335 
THR CA    CB     sing N N 336 
THR CA    HA     sing N N 337 
THR C     O      doub N N 338 
THR C     OXT    sing N N 339 
THR CB    OG1    sing N N 340 
THR CB    CG2    sing N N 341 
THR CB    HB     sing N N 342 
THR OG1   HG1    sing N N 343 
THR CG2   HG21   sing N N 344 
THR CG2   HG22   sing N N 345 
THR CG2   HG23   sing N N 346 
THR OXT   HXT    sing N N 347 
TRP N     CA     sing N N 348 
TRP N     H      sing N N 349 
TRP N     H2     sing N N 350 
TRP CA    C      sing N N 351 
TRP CA    CB     sing N N 352 
TRP CA    HA     sing N N 353 
TRP C     O      doub N N 354 
TRP C     OXT    sing N N 355 
TRP CB    CG     sing N N 356 
TRP CB    HB2    sing N N 357 
TRP CB    HB3    sing N N 358 
TRP CG    CD1    doub Y N 359 
TRP CG    CD2    sing Y N 360 
TRP CD1   NE1    sing Y N 361 
TRP CD1   HD1    sing N N 362 
TRP CD2   CE2    doub Y N 363 
TRP CD2   CE3    sing Y N 364 
TRP NE1   CE2    sing Y N 365 
TRP NE1   HE1    sing N N 366 
TRP CE2   CZ2    sing Y N 367 
TRP CE3   CZ3    doub Y N 368 
TRP CE3   HE3    sing N N 369 
TRP CZ2   CH2    doub Y N 370 
TRP CZ2   HZ2    sing N N 371 
TRP CZ3   CH2    sing Y N 372 
TRP CZ3   HZ3    sing N N 373 
TRP CH2   HH2    sing N N 374 
TRP OXT   HXT    sing N N 375 
TYR N     CA     sing N N 376 
TYR N     H      sing N N 377 
TYR N     H2     sing N N 378 
TYR CA    C      sing N N 379 
TYR CA    CB     sing N N 380 
TYR CA    HA     sing N N 381 
TYR C     O      doub N N 382 
TYR C     OXT    sing N N 383 
TYR CB    CG     sing N N 384 
TYR CB    HB2    sing N N 385 
TYR CB    HB3    sing N N 386 
TYR CG    CD1    doub Y N 387 
TYR CG    CD2    sing Y N 388 
TYR CD1   CE1    sing Y N 389 
TYR CD1   HD1    sing N N 390 
TYR CD2   CE2    doub Y N 391 
TYR CD2   HD2    sing N N 392 
TYR CE1   CZ     doub Y N 393 
TYR CE1   HE1    sing N N 394 
TYR CE2   CZ     sing Y N 395 
TYR CE2   HE2    sing N N 396 
TYR CZ    OH     sing N N 397 
TYR OH    HH     sing N N 398 
TYR OXT   HXT    sing N N 399 
VAL N     CA     sing N N 400 
VAL N     H      sing N N 401 
VAL N     H2     sing N N 402 
VAL CA    C      sing N N 403 
VAL CA    CB     sing N N 404 
VAL CA    HA     sing N N 405 
VAL C     O      doub N N 406 
VAL C     OXT    sing N N 407 
VAL CB    CG1    sing N N 408 
VAL CB    CG2    sing N N 409 
VAL CB    HB     sing N N 410 
VAL CG1   HG11   sing N N 411 
VAL CG1   HG12   sing N N 412 
VAL CG1   HG13   sing N N 413 
VAL CG2   HG21   sing N N 414 
VAL CG2   HG22   sing N N 415 
VAL CG2   HG23   sing N N 416 
VAL OXT   HXT    sing N N 417 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-20 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9EQ2 
_em_admin.last_update        2025-04-16 
_em_admin.map_release_date   2025-01-29 
_em_admin.title              'Arabidopsis thaliana R2T complex' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 25  mM HEPES 1 'N-(2-Hydroxyethyl)piperazine-N-(2-ethanesulfonic acid)' 
1 300 mM NaCl  2 'Sodium chloride'                                        
1 1   mM DTT   3 1,4-Dithiothreitol                                       
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.7 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          3702 
_em_entity_assembly_naturalsource.organism             'Arabidopsis thaliana' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.12 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   2334954 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? RELION          4.0         
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?               ?           
MASKING                         ? 3  ? ? ? ?               ?           
'CTF CORRECTION'                ? 4  1 ? ? CTFFIND         4.1         
'LAYERLINE INDEXING'            ? 5  ? ? ? ?               ?           
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?               ?           
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF ChimeraX' ?           
OTHER                           ? 8  ? ? ? ?               ?           
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? cryoSPARC       v4.3.1      
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? RELION          4.0         
CLASSIFICATION                  ? 11 1 ? ? RELION          4.0         
RECONSTRUCTION                  ? 12 1 ? ? RELION          4.0         
'MODEL REFINEMENT'              ? 13 ? 1 ? ISOLDE          1.7         
'MODEL REFINEMENT'              ? 14 ? 1 ? PHENIX          1.20.1-4487 
'MODEL REFINEMENT'              ? 15 ? 1 ? Coot            0.9.8.5     
'VOLUME SELECTION'              ? 16 1 1 1 ?               ?           
'SERIES ALIGNMENT'              ? 17 1 1 1 ?               ?           
'MOLECULAR REPLACEMENT'         ? 18 1 1 1 ?               ?           
'LATTICE DISTORTION CORRECTION' ? 19 1 1 1 ?               ?           
'SYMMETRY DETERMINATION'        ? 20 1 1 1 ?               ?           
'CRYSTALLOGRAPHY MERGING'       ? 21 1 1 1 ?               ?           
# 
_em_specimen.concentration           0.8 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Agencia Estatal de Investigacion (AEI)' 
_pdbx_audit_support.country                Spain 
_pdbx_audit_support.grant_number           PID2020-114429RB-I00 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9EQ2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N     . ILE A 1 47  ? 122.818 177.417 187.966 1.00 33.33  ? 18  ILE A N     1 
ATOM   2     C CA    . ILE A 1 47  ? 122.107 177.873 189.192 1.00 33.33  ? 18  ILE A CA    1 
ATOM   3     C C     . ILE A 1 47  ? 122.345 179.366 189.410 1.00 33.33  ? 18  ILE A C     1 
ATOM   4     O O     . ILE A 1 47  ? 123.014 179.766 190.363 1.00 33.33  ? 18  ILE A O     1 
ATOM   5     C CB    . ILE A 1 47  ? 122.542 177.049 190.426 1.00 33.33  ? 18  ILE A CB    1 
ATOM   6     C CG1   . ILE A 1 47  ? 124.064 176.871 190.452 1.00 33.33  ? 18  ILE A CG1   1 
ATOM   7     C CG2   . ILE A 1 47  ? 121.855 175.693 190.420 1.00 33.33  ? 18  ILE A CG2   1 
ATOM   8     C CD1   . ILE A 1 47  ? 124.618 176.515 191.814 1.00 33.33  ? 18  ILE A CD1   1 
ATOM   9     N N     . ALA A 1 48  ? 121.810 180.187 188.502 1.00 32.39  ? 19  ALA A N     1 
ATOM   10    C CA    . ALA A 1 48  ? 121.846 181.632 188.704 1.00 32.39  ? 19  ALA A CA    1 
ATOM   11    C C     . ALA A 1 48  ? 121.057 182.015 189.946 1.00 32.39  ? 19  ALA A C     1 
ATOM   12    O O     . ALA A 1 48  ? 121.473 182.889 190.715 1.00 32.39  ? 19  ALA A O     1 
ATOM   13    C CB    . ALA A 1 48  ? 121.296 182.351 187.474 1.00 32.39  ? 19  ALA A CB    1 
ATOM   14    N N     . THR A 1 49  ? 119.916 181.365 190.154 1.00 33.12  ? 20  THR A N     1 
ATOM   15    C CA    . THR A 1 49  ? 119.199 181.439 191.414 1.00 33.12  ? 20  THR A CA    1 
ATOM   16    C C     . THR A 1 49  ? 119.971 180.641 192.471 1.00 33.12  ? 20  THR A C     1 
ATOM   17    O O     . THR A 1 49  ? 121.013 180.039 192.198 1.00 33.12  ? 20  THR A O     1 
ATOM   18    C CB    . THR A 1 49  ? 117.773 180.911 191.217 1.00 33.12  ? 20  THR A CB    1 
ATOM   19    O OG1   . THR A 1 49  ? 117.317 181.257 189.905 1.00 33.12  ? 20  THR A OG1   1 
ATOM   20    C CG2   . THR A 1 49  ? 116.775 181.491 192.224 1.00 33.12  ? 20  THR A CG2   1 
ATOM   21    N N     . HIS A 1 50  ? 119.438 180.577 193.696 1.00 32.52  ? 21  HIS A N     1 
ATOM   22    C CA    . HIS A 1 50  ? 120.035 179.772 194.799 1.00 32.52  ? 21  HIS A CA    1 
ATOM   23    C C     . HIS A 1 50  ? 121.419 180.298 195.188 1.00 32.52  ? 21  HIS A C     1 
ATOM   24    O O     . HIS A 1 50  ? 122.175 179.514 195.781 1.00 32.52  ? 21  HIS A O     1 
ATOM   25    C CB    . HIS A 1 50  ? 120.115 178.288 194.433 1.00 32.52  ? 21  HIS A CB    1 
ATOM   26    C CG    . HIS A 1 50  ? 119.006 177.796 193.577 1.00 32.52  ? 21  HIS A CG    1 
ATOM   27    N ND1   . HIS A 1 50  ? 117.793 177.383 194.077 1.00 32.52  ? 21  HIS A ND1   1 
ATOM   28    C CD2   . HIS A 1 50  ? 118.933 177.650 192.253 1.00 32.52  ? 21  HIS A CD2   1 
ATOM   29    C CE1   . HIS A 1 50  ? 117.022 177.003 193.071 1.00 32.52  ? 21  HIS A CE1   1 
ATOM   30    N NE2   . HIS A 1 50  ? 117.693 177.156 191.956 1.00 32.52  ? 21  HIS A NE2   1 
ATOM   31    N N     . THR A 1 51  ? 121.741 181.560 194.905 1.00 32.68  ? 22  THR A N     1 
ATOM   32    C CA    . THR A 1 51  ? 123.033 182.176 195.283 1.00 32.68  ? 22  THR A CA    1 
ATOM   33    C C     . THR A 1 51  ? 122.966 182.540 196.749 1.00 32.68  ? 22  THR A C     1 
ATOM   34    O O     . THR A 1 51  ? 123.989 182.356 197.444 1.00 32.68  ? 22  THR A O     1 
ATOM   35    C CB    . THR A 1 51  ? 123.306 183.389 194.398 1.00 32.68  ? 22  THR A CB    1 
ATOM   36    O OG1   . THR A 1 51  ? 122.105 184.155 194.410 1.00 32.68  ? 22  THR A OG1   1 
ATOM   37    C CG2   . THR A 1 51  ? 123.654 182.989 192.976 1.00 32.68  ? 22  THR A CG2   1 
ATOM   38    N N     . HIS A 1 52  ? 121.814 183.025 197.221 1.00 32.36  ? 23  HIS A N     1 
ATOM   39    C CA    . HIS A 1 52  ? 121.618 183.379 198.625 1.00 32.36  ? 23  HIS A CA    1 
ATOM   40    C C     . HIS A 1 52  ? 121.819 182.195 199.566 1.00 32.36  ? 23  HIS A C     1 
ATOM   41    O O     . HIS A 1 52  ? 122.190 182.393 200.728 1.00 32.36  ? 23  HIS A O     1 
ATOM   42    C CB    . HIS A 1 52  ? 120.220 183.968 198.821 1.00 32.36  ? 23  HIS A CB    1 
ATOM   43    C CG    . HIS A 1 52  ? 119.105 183.032 198.469 1.00 32.36  ? 23  HIS A CG    1 
ATOM   44    N ND1   . HIS A 1 52  ? 118.701 182.013 199.304 1.00 32.36  ? 23  HIS A ND1   1 
ATOM   45    C CD2   . HIS A 1 52  ? 118.319 182.951 197.371 1.00 32.36  ? 23  HIS A CD2   1 
ATOM   46    C CE1   . HIS A 1 52  ? 117.708 181.352 198.742 1.00 32.36  ? 23  HIS A CE1   1 
ATOM   47    N NE2   . HIS A 1 52  ? 117.456 181.900 197.569 1.00 32.36  ? 23  HIS A NE2   1 
ATOM   48    N N     . ILE A 1 53  ? 121.577 180.973 199.103 1.00 31.32  ? 24  ILE A N     1 
ATOM   49    C CA    . ILE A 1 53  ? 121.730 179.793 199.949 1.00 31.32  ? 24  ILE A CA    1 
ATOM   50    C C     . ILE A 1 53  ? 123.218 179.518 200.120 1.00 31.32  ? 24  ILE A C     1 
ATOM   51    O O     . ILE A 1 53  ? 123.945 179.366 199.134 1.00 31.32  ? 24  ILE A O     1 
ATOM   52    C CB    . ILE A 1 53  ? 120.998 178.584 199.345 1.00 31.32  ? 24  ILE A CB    1 
ATOM   53    C CG1   . ILE A 1 53  ? 119.489 178.753 199.520 1.00 31.32  ? 24  ILE A CG1   1 
ATOM   54    C CG2   . ILE A 1 53  ? 121.448 177.257 199.981 1.00 31.32  ? 24  ILE A CG2   1 
ATOM   55    C CD1   . ILE A 1 53  ? 118.702 178.286 198.337 1.00 31.32  ? 24  ILE A CD1   1 
ATOM   56    N N     . LYS A 1 54  ? 123.665 179.442 201.374 1.00 33.99  ? 25  LYS A N     1 
ATOM   57    C CA    . LYS A 1 54  ? 125.057 179.199 201.750 1.00 33.99  ? 25  LYS A CA    1 
ATOM   58    C C     . LYS A 1 54  ? 125.124 178.121 202.823 1.00 33.99  ? 25  LYS A C     1 
ATOM   59    O O     . LYS A 1 54  ? 125.793 178.268 203.848 1.00 33.99  ? 25  LYS A O     1 
ATOM   60    C CB    . LYS A 1 54  ? 125.744 180.475 202.247 1.00 33.99  ? 25  LYS A CB    1 
ATOM   61    C CG    . LYS A 1 54  ? 125.581 181.728 201.374 1.00 33.99  ? 25  LYS A CG    1 
ATOM   62    C CD    . LYS A 1 54  ? 126.243 181.597 199.994 1.00 33.99  ? 25  LYS A CD    1 
ATOM   63    C CE    . LYS A 1 54  ? 127.765 181.697 200.042 1.00 33.99  ? 25  LYS A CE    1 
ATOM   64    N NZ    . LYS A 1 54  ? 128.305 182.303 198.793 1.00 33.99  ? 25  LYS A NZ    1 
ATOM   65    N N     . GLY A 1 55  ? 124.413 177.021 202.590 1.00 32.01  ? 26  GLY A N     1 
ATOM   66    C CA    . GLY A 1 55  ? 124.339 175.900 203.505 1.00 32.01  ? 26  GLY A CA    1 
ATOM   67    C C     . GLY A 1 55  ? 123.019 175.860 204.255 1.00 32.01  ? 26  GLY A C     1 
ATOM   68    O O     . GLY A 1 55  ? 122.174 176.752 204.157 1.00 32.01  ? 26  GLY A O     1 
ATOM   69    N N     . LEU A 1 56  ? 122.850 174.782 205.023 1.00 31.03  ? 27  LEU A N     1 
ATOM   70    C CA    . LEU A 1 56  ? 121.599 174.578 205.745 1.00 31.03  ? 27  LEU A CA    1 
ATOM   71    C C     . LEU A 1 56  ? 121.415 175.594 206.864 1.00 31.03  ? 27  LEU A C     1 
ATOM   72    O O     . LEU A 1 56  ? 120.278 175.951 207.190 1.00 31.03  ? 27  LEU A O     1 
ATOM   73    C CB    . LEU A 1 56  ? 121.549 173.159 206.311 1.00 31.03  ? 27  LEU A CB    1 
ATOM   74    C CG    . LEU A 1 56  ? 121.585 171.990 205.321 1.00 31.03  ? 27  LEU A CG    1 
ATOM   75    C CD1   . LEU A 1 56  ? 121.590 170.677 206.080 1.00 31.03  ? 27  LEU A CD1   1 
ATOM   76    C CD2   . LEU A 1 56  ? 120.419 172.026 204.344 1.00 31.03  ? 27  LEU A CD2   1 
ATOM   77    N N     . GLY A 1 57  ? 122.503 176.065 207.466 1.00 33.02  ? 28  GLY A N     1 
ATOM   78    C CA    . GLY A 1 57  ? 122.397 177.031 208.541 1.00 33.02  ? 28  GLY A CA    1 
ATOM   79    C C     . GLY A 1 57  ? 121.809 176.428 209.798 1.00 33.02  ? 28  GLY A C     1 
ATOM   80    O O     . GLY A 1 57  ? 120.695 176.779 210.197 1.00 33.02  ? 28  GLY A O     1 
ATOM   81    N N     . LEU A 1 58  ? 122.559 175.524 210.424 1.00 35.89  ? 29  LEU A N     1 
ATOM   82    C CA    . LEU A 1 58  ? 122.130 174.756 211.582 1.00 35.89  ? 29  LEU A CA    1 
ATOM   83    C C     . LEU A 1 58  ? 122.965 175.120 212.802 1.00 35.89  ? 29  LEU A C     1 
ATOM   84    O O     . LEU A 1 58  ? 124.094 175.604 212.692 1.00 35.89  ? 29  LEU A O     1 
ATOM   85    C CB    . LEU A 1 58  ? 122.253 173.251 211.318 1.00 35.89  ? 29  LEU A CB    1 
ATOM   86    C CG    . LEU A 1 58  ? 121.672 172.706 210.012 1.00 35.89  ? 29  LEU A CG    1 
ATOM   87    C CD1   . LEU A 1 58  ? 122.026 171.246 209.849 1.00 35.89  ? 29  LEU A CD1   1 
ATOM   88    C CD2   . LEU A 1 58  ? 120.170 172.897 209.971 1.00 35.89  ? 29  LEU A CD2   1 
ATOM   89    N N     . GLU A 1 59  ? 122.387 174.877 213.975 1.00 41.46  ? 30  GLU A N     1 
ATOM   90    C CA    . GLU A 1 59  ? 123.110 175.011 215.224 1.00 41.46  ? 30  GLU A CA    1 
ATOM   91    C C     . GLU A 1 59  ? 124.060 173.825 215.374 1.00 41.46  ? 30  GLU A C     1 
ATOM   92    O O     . GLU A 1 59  ? 123.959 172.848 214.629 1.00 41.46  ? 30  GLU A O     1 
ATOM   93    C CB    . GLU A 1 59  ? 122.132 175.085 216.396 1.00 41.46  ? 30  GLU A CB    1 
ATOM   94    C CG    . GLU A 1 59  ? 121.475 176.444 216.567 1.00 41.46  ? 30  GLU A CG    1 
ATOM   95    C CD    . GLU A 1 59  ? 120.060 176.344 217.102 1.00 41.46  ? 30  GLU A CD    1 
ATOM   96    O OE1   . GLU A 1 59  ? 119.813 175.484 217.973 1.00 41.46  ? 30  GLU A OE1   1 
ATOM   97    O OE2   . GLU A 1 59  ? 119.195 177.124 216.653 1.00 41.46  ? 30  GLU A OE2   1 
ATOM   98    N N     . PRO A 1 60  ? 125.023 173.889 216.306 1.00 44.72  ? 31  PRO A N     1 
ATOM   99    C CA    . PRO A 1 60  ? 125.859 172.700 216.556 1.00 44.72  ? 31  PRO A CA    1 
ATOM   100   C C     . PRO A 1 60  ? 125.068 171.494 217.032 1.00 44.72  ? 31  PRO A C     1 
ATOM   101   O O     . PRO A 1 60  ? 125.451 170.355 216.737 1.00 44.72  ? 31  PRO A O     1 
ATOM   102   C CB    . PRO A 1 60  ? 126.850 173.180 217.627 1.00 44.72  ? 31  PRO A CB    1 
ATOM   103   C CG    . PRO A 1 60  ? 126.828 174.658 217.548 1.00 44.72  ? 31  PRO A CG    1 
ATOM   104   C CD    . PRO A 1 60  ? 125.442 175.027 217.145 1.00 44.72  ? 31  PRO A CD    1 
ATOM   105   N N     . THR A 1 61  ? 123.971 171.711 217.761 1.00 44.45  ? 32  THR A N     1 
ATOM   106   C CA    . THR A 1 61  ? 123.104 170.603 218.158 1.00 44.45  ? 32  THR A CA    1 
ATOM   107   C C     . THR A 1 61  ? 122.389 169.955 216.973 1.00 44.45  ? 32  THR A C     1 
ATOM   108   O O     . THR A 1 61  ? 121.913 168.822 217.109 1.00 44.45  ? 32  THR A O     1 
ATOM   109   C CB    . THR A 1 61  ? 122.066 171.058 219.200 1.00 44.45  ? 32  THR A CB    1 
ATOM   110   O OG1   . THR A 1 61  ? 121.196 169.963 219.512 1.00 44.45  ? 32  THR A OG1   1 
ATOM   111   C CG2   . THR A 1 61  ? 121.211 172.258 218.727 1.00 44.45  ? 32  THR A CG2   1 
ATOM   112   N N     . GLY A 1 62  ? 122.289 170.646 215.831 1.00 44.51  ? 33  GLY A N     1 
ATOM   113   C CA    . GLY A 1 62  ? 121.723 170.107 214.613 1.00 44.51  ? 33  GLY A CA    1 
ATOM   114   C C     . GLY A 1 62  ? 120.320 170.583 214.295 1.00 44.51  ? 33  GLY A C     1 
ATOM   115   O O     . GLY A 1 62  ? 119.891 170.453 213.143 1.00 44.51  ? 33  GLY A O     1 
ATOM   116   N N     . ILE A 1 63  ? 119.602 171.131 215.265 1.00 40.62  ? 34  ILE A N     1 
ATOM   117   C CA    . ILE A 1 63  ? 118.263 171.660 214.984 1.00 40.62  ? 34  ILE A CA    1 
ATOM   118   C C     . ILE A 1 63  ? 118.413 172.932 214.149 1.00 40.62  ? 34  ILE A C     1 
ATOM   119   O O     . ILE A 1 63  ? 119.266 173.772 214.482 1.00 40.62  ? 34  ILE A O     1 
ATOM   120   C CB    . ILE A 1 63  ? 117.509 171.934 216.299 1.00 40.62  ? 34  ILE A CB    1 
ATOM   121   C CG1   . ILE A 1 63  ? 117.279 170.616 217.085 1.00 40.62  ? 34  ILE A CG1   1 
ATOM   122   C CG2   . ILE A 1 63  ? 116.180 172.699 216.031 1.00 40.62  ? 34  ILE A CG2   1 
ATOM   123   C CD1   . ILE A 1 63  ? 118.362 170.268 218.102 1.00 40.62  ? 34  ILE A CD1   1 
ATOM   124   N N     . PRO A 1 64  ? 117.650 173.139 213.067 1.00 36.44  ? 35  PRO A N     1 
ATOM   125   C CA    . PRO A 1 64  ? 117.899 174.328 212.244 1.00 36.44  ? 35  PRO A CA    1 
ATOM   126   C C     . PRO A 1 64  ? 117.462 175.611 212.927 1.00 36.44  ? 35  PRO A C     1 
ATOM   127   O O     . PRO A 1 64  ? 116.554 175.626 213.760 1.00 36.44  ? 35  PRO A O     1 
ATOM   128   C CB    . PRO A 1 64  ? 117.066 174.079 210.979 1.00 36.44  ? 35  PRO A CB    1 
ATOM   129   C CG    . PRO A 1 64  ? 116.607 172.690 211.062 1.00 36.44  ? 35  PRO A CG    1 
ATOM   130   C CD    . PRO A 1 64  ? 116.514 172.384 212.507 1.00 36.44  ? 35  PRO A CD    1 
ATOM   131   N N     . ILE A 1 65  ? 118.127 176.697 212.551 1.00 35.87  ? 36  ILE A N     1 
ATOM   132   C CA    . ILE A 1 65  ? 117.715 178.039 212.946 1.00 35.87  ? 36  ILE A CA    1 
ATOM   133   C C     . ILE A 1 65  ? 116.582 178.453 212.017 1.00 35.87  ? 36  ILE A C     1 
ATOM   134   O O     . ILE A 1 65  ? 116.568 178.091 210.834 1.00 35.87  ? 36  ILE A O     1 
ATOM   135   C CB    . ILE A 1 65  ? 118.902 179.033 212.892 1.00 35.87  ? 36  ILE A CB    1 
ATOM   136   C CG1   . ILE A 1 65  ? 120.149 178.500 213.644 1.00 35.87  ? 36  ILE A CG1   1 
ATOM   137   C CG2   . ILE A 1 65  ? 118.508 180.406 213.511 1.00 35.87  ? 36  ILE A CG2   1 
ATOM   138   C CD1   . ILE A 1 65  ? 121.404 179.347 213.488 1.00 35.87  ? 36  ILE A CD1   1 
ATOM   139   N N     . LYS A 1 66  ? 115.614 179.200 212.553 1.00 36.07  ? 37  LYS A N     1 
ATOM   140   C CA    . LYS A 1 66  ? 114.452 179.597 211.762 1.00 36.07  ? 37  LYS A CA    1 
ATOM   141   C C     . LYS A 1 66  ? 114.811 180.518 210.602 1.00 36.07  ? 37  LYS A C     1 
ATOM   142   O O     . LYS A 1 66  ? 114.050 180.587 209.631 1.00 36.07  ? 37  LYS A O     1 
ATOM   143   C CB    . LYS A 1 66  ? 113.422 180.283 212.659 1.00 36.07  ? 37  LYS A CB    1 
ATOM   144   C CG    . LYS A 1 66  ? 112.065 180.496 212.004 1.00 36.07  ? 37  LYS A CG    1 
ATOM   145   C CD    . LYS A 1 66  ? 111.025 180.946 213.017 1.00 36.07  ? 37  LYS A CD    1 
ATOM   146   C CE    . LYS A 1 66  ? 109.646 181.043 212.392 1.00 36.07  ? 37  LYS A CE    1 
ATOM   147   N NZ    . LYS A 1 66  ? 108.598 181.339 213.406 1.00 36.07  ? 37  LYS A NZ    1 
ATOM   148   N N     . LEU A 1 67  ? 115.936 181.233 210.678 1.00 33.73  ? 38  LEU A N     1 
ATOM   149   C CA    . LEU A 1 67  ? 116.356 182.133 209.604 1.00 33.73  ? 38  LEU A CA    1 
ATOM   150   C C     . LEU A 1 67  ? 117.881 182.209 209.654 1.00 33.73  ? 38  LEU A C     1 
ATOM   151   O O     . LEU A 1 67  ? 118.444 182.908 210.501 1.00 33.73  ? 38  LEU A O     1 
ATOM   152   C CB    . LEU A 1 67  ? 115.703 183.502 209.759 1.00 33.73  ? 38  LEU A CB    1 
ATOM   153   C CG    . LEU A 1 67  ? 115.554 184.361 208.500 1.00 33.73  ? 38  LEU A CG    1 
ATOM   154   C CD1   . LEU A 1 67  ? 114.462 185.404 208.699 1.00 33.73  ? 38  LEU A CD1   1 
ATOM   155   C CD2   . LEU A 1 67  ? 116.868 185.024 208.097 1.00 33.73  ? 38  LEU A CD2   1 
ATOM   156   N N     . ALA A 1 68  ? 118.539 181.476 208.760 1.00 30.90  ? 39  ALA A N     1 
ATOM   157   C CA    . ALA A 1 68  ? 119.995 181.438 208.738 1.00 30.90  ? 39  ALA A CA    1 
ATOM   158   C C     . ALA A 1 68  ? 120.463 180.790 207.445 1.00 30.90  ? 39  ALA A C     1 
ATOM   159   O O     . ALA A 1 68  ? 119.823 179.867 206.935 1.00 30.90  ? 39  ALA A O     1 
ATOM   160   C CB    . ALA A 1 68  ? 120.555 180.669 209.941 1.00 30.90  ? 39  ALA A CB    1 
ATOM   161   N N     . ALA A 1 69  ? 121.590 181.285 206.930 1.00 31.43  ? 40  ALA A N     1 
ATOM   162   C CA    . ALA A 1 69  ? 122.238 180.737 205.737 1.00 31.43  ? 40  ALA A CA    1 
ATOM   163   C C     . ALA A 1 69  ? 121.337 180.802 204.508 1.00 31.43  ? 40  ALA A C     1 
ATOM   164   O O     . ALA A 1 69  ? 121.421 179.949 203.623 1.00 31.43  ? 40  ALA A O     1 
ATOM   165   C CB    . ALA A 1 69  ? 122.701 179.297 205.973 1.00 31.43  ? 40  ALA A CB    1 
ATOM   166   N N     . GLY A 1 70  ? 120.466 181.809 204.442 1.00 30.56  ? 41  GLY A N     1 
ATOM   167   C CA    . GLY A 1 70  ? 119.551 181.977 203.337 1.00 30.56  ? 41  GLY A CA    1 
ATOM   168   C C     . GLY A 1 70  ? 118.255 181.202 203.452 1.00 30.56  ? 41  GLY A C     1 
ATOM   169   O O     . GLY A 1 70  ? 117.297 181.525 202.743 1.00 30.56  ? 41  GLY A O     1 
ATOM   170   N N     . PHE A 1 71  ? 118.182 180.204 204.323 1.00 30.69  ? 42  PHE A N     1 
ATOM   171   C CA    . PHE A 1 71  ? 116.976 179.339 204.384 1.00 30.69  ? 42  PHE A CA    1 
ATOM   172   C C     . PHE A 1 71  ? 115.915 179.981 205.254 1.00 30.69  ? 42  PHE A C     1 
ATOM   173   O O     . PHE A 1 71  ? 116.271 180.439 206.352 1.00 30.69  ? 42  PHE A O     1 
ATOM   174   C CB    . PHE A 1 71  ? 117.359 177.967 204.936 1.00 30.69  ? 42  PHE A CB    1 
ATOM   175   C CG    . PHE A 1 71  ? 117.700 176.913 203.897 1.00 30.69  ? 42  PHE A CG    1 
ATOM   176   C CD1   . PHE A 1 71  ? 118.993 176.784 203.412 1.00 30.69  ? 42  PHE A CD1   1 
ATOM   177   C CD2   . PHE A 1 71  ? 116.731 176.033 203.438 1.00 30.69  ? 42  PHE A CD2   1 
ATOM   178   C CE1   . PHE A 1 71  ? 119.299 175.812 202.477 1.00 30.69  ? 42  PHE A CE1   1 
ATOM   179   C CE2   . PHE A 1 71  ? 117.044 175.064 202.503 1.00 30.69  ? 42  PHE A CE2   1 
ATOM   180   C CZ    . PHE A 1 71  ? 118.325 174.956 202.027 1.00 30.69  ? 42  PHE A CZ    1 
ATOM   181   N N     . VAL A 1 72  ? 114.665 180.036 204.795 1.00 33.90  ? 43  VAL A N     1 
ATOM   182   C CA    . VAL A 1 72  ? 113.531 180.535 205.625 1.00 33.90  ? 43  VAL A CA    1 
ATOM   183   C C     . VAL A 1 72  ? 112.622 179.331 205.896 1.00 33.90  ? 43  VAL A C     1 
ATOM   184   O O     . VAL A 1 72  ? 112.309 178.606 204.944 1.00 33.90  ? 43  VAL A O     1 
ATOM   185   C CB    . VAL A 1 72  ? 112.759 181.702 204.983 1.00 33.90  ? 43  VAL A CB    1 
ATOM   186   C CG1   . VAL A 1 72  ? 113.655 182.547 204.092 1.00 33.90  ? 43  VAL A CG1   1 
ATOM   187   C CG2   . VAL A 1 72  ? 111.524 181.264 204.207 1.00 33.90  ? 43  VAL A CG2   1 
ATOM   188   N N     . GLY A 1 73  ? 112.273 179.087 207.153 1.00 31.93  ? 44  GLY A N     1 
ATOM   189   C CA    . GLY A 1 73  ? 111.358 177.993 207.518 1.00 31.93  ? 44  GLY A CA    1 
ATOM   190   C C     . GLY A 1 73  ? 111.859 176.667 207.006 1.00 31.93  ? 44  GLY A C     1 
ATOM   191   O O     . GLY A 1 73  ? 113.079 176.547 206.825 1.00 31.93  ? 44  GLY A O     1 
ATOM   192   N N     . GLN A 1 74  ? 110.965 175.700 206.787 1.00 31.83  ? 45  GLN A N     1 
ATOM   193   C CA    . GLN A 1 74  ? 111.356 174.397 206.254 1.00 31.83  ? 45  GLN A CA    1 
ATOM   194   C C     . GLN A 1 74  ? 112.197 173.624 207.271 1.00 31.83  ? 45  GLN A C     1 
ATOM   195   O O     . GLN A 1 74  ? 113.252 173.074 206.955 1.00 31.83  ? 45  GLN A O     1 
ATOM   196   C CB    . GLN A 1 74  ? 112.104 174.569 204.929 1.00 31.83  ? 45  GLN A CB    1 
ATOM   197   C CG    . GLN A 1 74  ? 112.128 173.345 204.039 1.00 31.83  ? 45  GLN A CG    1 
ATOM   198   C CD    . GLN A 1 74  ? 110.779 173.023 203.436 1.00 31.83  ? 45  GLN A CD    1 
ATOM   199   O OE1   . GLN A 1 74  ? 110.072 172.134 203.906 1.00 31.83  ? 45  GLN A OE1   1 
ATOM   200   N NE2   . GLN A 1 74  ? 110.417 173.744 202.385 1.00 31.83  ? 45  GLN A NE2   1 
ATOM   201   N N     . LEU A 1 75  ? 111.714 173.589 208.513 1.00 30.80  ? 46  LEU A N     1 
ATOM   202   C CA    . LEU A 1 75  ? 112.551 173.125 209.614 1.00 30.80  ? 46  LEU A CA    1 
ATOM   203   C C     . LEU A 1 75  ? 112.727 171.611 209.594 1.00 30.80  ? 46  LEU A C     1 
ATOM   204   O O     . LEU A 1 75  ? 113.822 171.110 209.871 1.00 30.80  ? 46  LEU A O     1 
ATOM   205   C CB    . LEU A 1 75  ? 111.956 173.577 210.947 1.00 30.80  ? 46  LEU A CB    1 
ATOM   206   C CG    . LEU A 1 75  ? 111.645 175.069 211.100 1.00 30.80  ? 46  LEU A CG    1 
ATOM   207   C CD1   . LEU A 1 75  ? 110.980 175.331 212.440 1.00 30.80  ? 46  LEU A CD1   1 
ATOM   208   C CD2   . LEU A 1 75  ? 112.899 175.911 210.951 1.00 30.80  ? 46  LEU A CD2   1 
ATOM   209   N N     . GLU A 1 76  ? 111.666 170.865 209.279 1.00 34.98  ? 47  GLU A N     1 
ATOM   210   C CA    . GLU A 1 76  ? 111.761 169.408 209.296 1.00 34.98  ? 47  GLU A CA    1 
ATOM   211   C C     . GLU A 1 76  ? 112.690 168.903 208.199 1.00 34.98  ? 47  GLU A C     1 
ATOM   212   O O     . GLU A 1 76  ? 113.571 168.070 208.449 1.00 34.98  ? 47  GLU A O     1 
ATOM   213   C CB    . GLU A 1 76  ? 110.372 168.789 209.147 1.00 34.98  ? 47  GLU A CB    1 
ATOM   214   C CG    . GLU A 1 76  ? 109.467 168.996 210.349 1.00 34.98  ? 47  GLU A CG    1 
ATOM   215   C CD    . GLU A 1 76  ? 108.287 168.044 210.360 1.00 34.98  ? 47  GLU A CD    1 
ATOM   216   O OE1   . GLU A 1 76  ? 107.774 167.718 209.269 1.00 34.98  ? 47  GLU A OE1   1 
ATOM   217   O OE2   . GLU A 1 76  ? 107.870 167.625 211.460 1.00 34.98  ? 47  GLU A OE2   1 
ATOM   218   N N     . ALA A 1 77  ? 112.520 169.413 206.978 1.00 29.83  ? 48  ALA A N     1 
ATOM   219   C CA    . ALA A 1 77  ? 113.372 168.972 205.881 1.00 29.83  ? 48  ALA A CA    1 
ATOM   220   C C     . ALA A 1 77  ? 114.808 169.438 206.077 1.00 29.83  ? 48  ALA A C     1 
ATOM   221   O O     . ALA A 1 77  ? 115.745 168.723 205.719 1.00 29.83  ? 48  ALA A O     1 
ATOM   222   C CB    . ALA A 1 77  ? 112.824 169.475 204.550 1.00 29.83  ? 48  ALA A CB    1 
ATOM   223   N N     . ARG A 1 78  ? 115.004 170.629 206.648 1.00 30.71  ? 49  ARG A N     1 
ATOM   224   C CA    . ARG A 1 78  ? 116.360 171.101 206.914 1.00 30.71  ? 49  ARG A CA    1 
ATOM   225   C C     . ARG A 1 78  ? 117.045 170.256 207.980 1.00 30.71  ? 49  ARG A C     1 
ATOM   226   O O     . ARG A 1 78  ? 118.237 169.948 207.862 1.00 30.71  ? 49  ARG A O     1 
ATOM   227   C CB    . ARG A 1 78  ? 116.335 172.566 207.336 1.00 30.71  ? 49  ARG A CB    1 
ATOM   228   C CG    . ARG A 1 78  ? 116.168 173.527 206.178 1.00 30.71  ? 49  ARG A CG    1 
ATOM   229   C CD    . ARG A 1 78  ? 115.878 174.936 206.655 1.00 30.71  ? 49  ARG A CD    1 
ATOM   230   N NE    . ARG A 1 78  ? 117.040 175.529 207.309 1.00 30.71  ? 49  ARG A NE    1 
ATOM   231   C CZ    . ARG A 1 78  ? 117.021 176.560 208.146 1.00 30.71  ? 49  ARG A CZ    1 
ATOM   232   N NH1   . ARG A 1 78  ? 115.898 177.186 208.469 1.00 30.71  ? 49  ARG A NH1   1 
ATOM   233   N NH2   . ARG A 1 78  ? 118.165 176.983 208.673 1.00 30.71  ? 49  ARG A NH2   1 
ATOM   234   N N     . GLU A 1 79  ? 116.313 169.878 209.032 1.00 35.40  ? 50  GLU A N     1 
ATOM   235   C CA    . GLU A 1 79  ? 116.880 169.002 210.053 1.00 35.40  ? 50  GLU A CA    1 
ATOM   236   C C     . GLU A 1 79  ? 117.236 167.642 209.470 1.00 35.40  ? 50  GLU A C     1 
ATOM   237   O O     . GLU A 1 79  ? 118.301 167.085 209.769 1.00 35.40  ? 50  GLU A O     1 
ATOM   238   C CB    . GLU A 1 79  ? 115.893 168.842 211.206 1.00 35.40  ? 50  GLU A CB    1 
ATOM   239   C CG    . GLU A 1 79  ? 116.501 168.249 212.465 1.00 35.40  ? 50  GLU A CG    1 
ATOM   240   C CD    . GLU A 1 79  ? 115.505 168.142 213.603 1.00 35.40  ? 50  GLU A CD    1 
ATOM   241   O OE1   . GLU A 1 79  ? 114.415 168.744 213.505 1.00 35.40  ? 50  GLU A OE1   1 
ATOM   242   O OE2   . GLU A 1 79  ? 115.812 167.450 214.596 1.00 35.40  ? 50  GLU A OE2   1 
ATOM   243   N N     . ALA A 1 80  ? 116.358 167.096 208.628 1.00 33.54  ? 51  ALA A N     1 
ATOM   244   C CA    . ALA A 1 80  ? 116.652 165.818 207.990 1.00 33.54  ? 51  ALA A CA    1 
ATOM   245   C C     . ALA A 1 80  ? 117.842 165.933 207.044 1.00 33.54  ? 51  ALA A C     1 
ATOM   246   O O     . ALA A 1 80  ? 118.654 165.008 206.948 1.00 33.54  ? 51  ALA A O     1 
ATOM   247   C CB    . ALA A 1 80  ? 115.420 165.313 207.249 1.00 33.54  ? 51  ALA A CB    1 
ATOM   248   N N     . ALA A 1 81  ? 117.964 167.058 206.339 1.00 30.10  ? 52  ALA A N     1 
ATOM   249   C CA    . ALA A 1 81  ? 119.107 167.268 205.458 1.00 30.10  ? 52  ALA A CA    1 
ATOM   250   C C     . ALA A 1 81  ? 120.403 167.357 206.250 1.00 30.10  ? 52  ALA A C     1 
ATOM   251   O O     . ALA A 1 81  ? 121.434 166.831 205.820 1.00 30.10  ? 52  ALA A O     1 
ATOM   252   C CB    . ALA A 1 81  ? 118.901 168.532 204.628 1.00 30.10  ? 52  ALA A CB    1 
ATOM   253   N N     . GLY A 1 82  ? 120.373 168.022 207.405 1.00 30.41  ? 53  GLY A N     1 
ATOM   254   C CA    . GLY A 1 82  ? 121.548 168.046 208.261 1.00 30.41  ? 53  GLY A CA    1 
ATOM   255   C C     . GLY A 1 82  ? 121.917 166.668 208.774 1.00 30.41  ? 53  GLY A C     1 
ATOM   256   O O     . GLY A 1 82  ? 123.099 166.314 208.853 1.00 30.41  ? 53  GLY A O     1 
ATOM   257   N N     . LEU A 1 83  ? 120.909 165.869 209.124 1.00 37.01  ? 54  LEU A N     1 
ATOM   258   C CA    . LEU A 1 83  ? 121.175 164.507 209.573 1.00 37.01  ? 54  LEU A CA    1 
ATOM   259   C C     . LEU A 1 83  ? 121.762 163.663 208.446 1.00 37.01  ? 54  LEU A C     1 
ATOM   260   O O     . LEU A 1 83  ? 122.655 162.841 208.678 1.00 37.01  ? 54  LEU A O     1 
ATOM   261   C CB    . LEU A 1 83  ? 119.888 163.881 210.117 1.00 37.01  ? 54  LEU A CB    1 
ATOM   262   C CG    . LEU A 1 83  ? 119.945 162.718 211.116 1.00 37.01  ? 54  LEU A CG    1 
ATOM   263   C CD1   . LEU A 1 83  ? 120.766 163.040 212.357 1.00 37.01  ? 54  LEU A CD1   1 
ATOM   264   C CD2   . LEU A 1 83  ? 118.537 162.324 211.534 1.00 37.01  ? 54  LEU A CD2   1 
ATOM   265   N N     . VAL A 1 84  ? 121.289 163.865 207.214 1.00 34.36  ? 55  VAL A N     1 
ATOM   266   C CA    . VAL A 1 84  ? 121.864 163.148 206.079 1.00 34.36  ? 55  VAL A CA    1 
ATOM   267   C C     . VAL A 1 84  ? 123.285 163.625 205.809 1.00 34.36  ? 55  VAL A C     1 
ATOM   268   O O     . VAL A 1 84  ? 124.132 162.838 205.379 1.00 34.36  ? 55  VAL A O     1 
ATOM   269   C CB    . VAL A 1 84  ? 120.969 163.289 204.832 1.00 34.36  ? 55  VAL A CB    1 
ATOM   270   C CG1   . VAL A 1 84  ? 121.693 162.815 203.559 1.00 34.36  ? 55  VAL A CG1   1 
ATOM   271   C CG2   . VAL A 1 84  ? 119.696 162.494 205.027 1.00 34.36  ? 55  VAL A CG2   1 
ATOM   272   N N     . VAL A 1 85  ? 123.566 164.912 206.025 1.00 33.38  ? 56  VAL A N     1 
ATOM   273   C CA    . VAL A 1 85  ? 124.930 165.414 205.871 1.00 33.38  ? 56  VAL A CA    1 
ATOM   274   C C     . VAL A 1 85  ? 125.850 164.733 206.874 1.00 33.38  ? 56  VAL A C     1 
ATOM   275   O O     . VAL A 1 85  ? 126.967 164.317 206.538 1.00 33.38  ? 56  VAL A O     1 
ATOM   276   C CB    . VAL A 1 85  ? 124.950 166.950 206.022 1.00 33.38  ? 56  VAL A CB    1 
ATOM   277   C CG1   . VAL A 1 85  ? 126.369 167.489 206.261 1.00 33.38  ? 56  VAL A CG1   1 
ATOM   278   C CG2   . VAL A 1 85  ? 124.339 167.617 204.793 1.00 33.38  ? 56  VAL A CG2   1 
ATOM   279   N N     . ASP A 1 86  ? 125.387 164.594 208.117 1.00 37.80  ? 57  ASP A N     1 
ATOM   280   C CA    . ASP A 1 86  ? 126.184 163.890 209.120 1.00 37.80  ? 57  ASP A CA    1 
ATOM   281   C C     . ASP A 1 86  ? 126.337 162.413 208.773 1.00 37.80  ? 57  ASP A C     1 
ATOM   282   O O     . ASP A 1 86  ? 127.378 161.816 209.066 1.00 37.80  ? 57  ASP A O     1 
ATOM   283   C CB    . ASP A 1 86  ? 125.554 164.030 210.517 1.00 37.80  ? 57  ASP A CB    1 
ATOM   284   C CG    . ASP A 1 86  ? 126.361 164.917 211.481 1.00 37.80  ? 57  ASP A CG    1 
ATOM   285   O OD1   . ASP A 1 86  ? 127.312 165.632 211.092 1.00 37.80  ? 57  ASP A OD1   1 
ATOM   286   O OD2   . ASP A 1 86  ? 126.023 164.890 212.680 1.00 37.80  ? 57  ASP A OD2   1 
ATOM   287   N N     . MET A 1 87  ? 125.318 161.808 208.159 1.00 39.43  ? 58  MET A N     1 
ATOM   288   C CA    . MET A 1 87  ? 125.446 160.431 207.684 1.00 39.43  ? 58  MET A CA    1 
ATOM   289   C C     . MET A 1 87  ? 126.491 160.329 206.577 1.00 39.43  ? 58  MET A C     1 
ATOM   290   O O     . MET A 1 87  ? 127.237 159.346 206.507 1.00 39.43  ? 58  MET A O     1 
ATOM   291   C CB    . MET A 1 87  ? 124.089 159.919 207.188 1.00 39.43  ? 58  MET A CB    1 
ATOM   292   C CG    . MET A 1 87  ? 123.199 159.332 208.289 1.00 39.43  ? 58  MET A CG    1 
ATOM   293   S SD    . MET A 1 87  ? 121.685 158.421 207.861 1.00 39.43  ? 58  MET A SD    1 
ATOM   294   C CE    . MET A 1 87  ? 121.600 158.452 206.074 1.00 39.43  ? 58  MET A CE    1 
ATOM   295   N N     . ILE A 1 88  ? 126.548 161.331 205.699 1.00 36.99  ? 59  ILE A N     1 
ATOM   296   C CA    . ILE A 1 88  ? 127.515 161.325 204.603 1.00 36.99  ? 59  ILE A CA    1 
ATOM   297   C C     . ILE A 1 88  ? 128.928 161.493 205.140 1.00 36.99  ? 59  ILE A C     1 
ATOM   298   O O     . ILE A 1 88  ? 129.882 160.929 204.591 1.00 36.99  ? 59  ILE A O     1 
ATOM   299   C CB    . ILE A 1 88  ? 127.177 162.424 203.574 1.00 36.99  ? 59  ILE A CB    1 
ATOM   300   C CG1   . ILE A 1 88  ? 125.884 162.094 202.825 1.00 36.99  ? 59  ILE A CG1   1 
ATOM   301   C CG2   . ILE A 1 88  ? 128.322 162.596 202.556 1.00 36.99  ? 59  ILE A CG2   1 
ATOM   302   C CD1   . ILE A 1 88  ? 125.198 163.296 202.188 1.00 36.99  ? 59  ILE A CD1   1 
ATOM   303   N N     . LYS A 1 89  ? 129.092 162.309 206.187 1.00 37.40  ? 60  LYS A N     1 
ATOM   304   C CA    . LYS A 1 89  ? 130.424 162.586 206.720 1.00 37.40  ? 60  LYS A CA    1 
ATOM   305   C C     . LYS A 1 89  ? 131.082 161.324 207.267 1.00 37.40  ? 60  LYS A C     1 
ATOM   306   O O     . LYS A 1 89  ? 132.295 161.137 207.117 1.00 37.40  ? 60  LYS A O     1 
ATOM   307   C CB    . LYS A 1 89  ? 130.335 163.655 207.807 1.00 37.40  ? 60  LYS A CB    1 
ATOM   308   C CG    . LYS A 1 89  ? 130.040 165.055 207.279 1.00 37.40  ? 60  LYS A CG    1 
ATOM   309   C CD    . LYS A 1 89  ? 131.283 165.759 206.752 1.00 37.40  ? 60  LYS A CD    1 
ATOM   310   C CE    . LYS A 1 89  ? 131.029 167.244 206.560 1.00 37.40  ? 60  LYS A CE    1 
ATOM   311   N NZ    . LYS A 1 89  ? 131.027 167.983 207.851 1.00 37.40  ? 60  LYS A NZ    1 
ATOM   312   N N     . GLN A 1 90  ? 130.297 160.442 207.889 1.00 42.26  ? 61  GLN A N     1 
ATOM   313   C CA    . GLN A 1 90  ? 130.786 159.190 208.451 1.00 42.26  ? 61  GLN A CA    1 
ATOM   314   C C     . GLN A 1 90  ? 130.670 158.011 207.476 1.00 42.26  ? 61  GLN A C     1 
ATOM   315   O O     . GLN A 1 90  ? 130.691 156.854 207.912 1.00 42.26  ? 61  GLN A O     1 
ATOM   316   C CB    . GLN A 1 90  ? 130.044 158.890 209.758 1.00 42.26  ? 61  GLN A CB    1 
ATOM   317   C CG    . GLN A 1 90  ? 130.321 159.915 210.862 1.00 42.26  ? 61  GLN A CG    1 
ATOM   318   C CD    . GLN A 1 90  ? 129.461 159.733 212.102 1.00 42.26  ? 61  GLN A CD    1 
ATOM   319   O OE1   . GLN A 1 90  ? 128.953 160.709 212.653 1.00 42.26  ? 61  GLN A OE1   1 
ATOM   320   N NE2   . GLN A 1 90  ? 129.312 158.492 212.563 1.00 42.26  ? 61  GLN A NE2   1 
ATOM   321   N N     . LYS A 1 91  ? 130.569 158.274 206.167 1.00 43.09  ? 62  LYS A N     1 
ATOM   322   C CA    . LYS A 1 91  ? 130.562 157.257 205.106 1.00 43.09  ? 62  LYS A CA    1 
ATOM   323   C C     . LYS A 1 91  ? 129.408 156.248 205.254 1.00 43.09  ? 62  LYS A C     1 
ATOM   324   O O     . LYS A 1 91  ? 129.457 155.145 204.698 1.00 43.09  ? 62  LYS A O     1 
ATOM   325   C CB    . LYS A 1 91  ? 131.932 156.542 205.019 1.00 43.09  ? 62  LYS A CB    1 
ATOM   326   C CG    . LYS A 1 91  ? 132.956 157.259 204.141 1.00 43.09  ? 62  LYS A CG    1 
ATOM   327   C CD    . LYS A 1 91  ? 133.403 158.587 204.728 1.00 43.09  ? 62  LYS A CD    1 
ATOM   328   C CE    . LYS A 1 91  ? 134.503 159.215 203.889 1.00 43.09  ? 62  LYS A CE    1 
ATOM   329   N NZ    . LYS A 1 91  ? 134.928 160.537 204.423 1.00 43.09  ? 62  LYS A NZ    1 
ATOM   330   N N     . LYS A 1 92  ? 128.326 156.621 205.944 1.00 43.80  ? 63  LYS A N     1 
ATOM   331   C CA    . LYS A 1 92  ? 127.210 155.708 206.163 1.00 43.80  ? 63  LYS A CA    1 
ATOM   332   C C     . LYS A 1 92  ? 126.230 155.645 204.994 1.00 43.80  ? 63  LYS A C     1 
ATOM   333   O O     . LYS A 1 92  ? 125.422 154.711 204.944 1.00 43.80  ? 63  LYS A O     1 
ATOM   334   C CB    . LYS A 1 92  ? 126.448 156.109 207.428 1.00 43.80  ? 63  LYS A CB    1 
ATOM   335   C CG    . LYS A 1 92  ? 127.296 156.236 208.703 1.00 43.80  ? 63  LYS A CG    1 
ATOM   336   C CD    . LYS A 1 92  ? 128.088 154.978 209.082 1.00 43.80  ? 63  LYS A CD    1 
ATOM   337   C CE    . LYS A 1 92  ? 127.189 153.789 209.396 1.00 43.80  ? 63  LYS A CE    1 
ATOM   338   N NZ    . LYS A 1 92  ? 127.975 152.607 209.845 1.00 43.80  ? 63  LYS A NZ    1 
ATOM   339   N N     . MET A 1 93  ? 126.282 156.592 204.055 1.00 41.28  ? 64  MET A N     1 
ATOM   340   C CA    . MET A 1 93  ? 125.337 156.645 202.943 1.00 41.28  ? 64  MET A CA    1 
ATOM   341   C C     . MET A 1 93  ? 125.780 155.832 201.727 1.00 41.28  ? 64  MET A C     1 
ATOM   342   O O     . MET A 1 93  ? 125.086 155.859 200.704 1.00 41.28  ? 64  MET A O     1 
ATOM   343   C CB    . MET A 1 93  ? 125.089 158.107 202.534 1.00 41.28  ? 64  MET A CB    1 
ATOM   344   C CG    . MET A 1 93  ? 123.953 158.746 203.304 1.00 41.28  ? 64  MET A CG    1 
ATOM   345   S SD    . MET A 1 93  ? 122.323 158.417 202.608 1.00 41.28  ? 64  MET A SD    1 
ATOM   346   C CE    . MET A 1 93  ? 122.355 159.440 201.139 1.00 41.28  ? 64  MET A CE    1 
ATOM   347   N N     . ALA A 1 94  ? 126.899 155.109 201.806 1.00 43.83  ? 65  ALA A N     1 
ATOM   348   C CA    . ALA A 1 94  ? 127.317 154.257 200.701 1.00 43.83  ? 65  ALA A CA    1 
ATOM   349   C C     . ALA A 1 94  ? 126.289 153.159 200.460 1.00 43.83  ? 65  ALA A C     1 
ATOM   350   O O     . ALA A 1 94  ? 125.813 152.518 201.401 1.00 43.83  ? 65  ALA A O     1 
ATOM   351   C CB    . ALA A 1 94  ? 128.686 153.646 200.995 1.00 43.83  ? 65  ALA A CB    1 
ATOM   352   N N     . GLY A 1 95  ? 125.942 152.953 199.193 1.00 42.81  ? 66  GLY A N     1 
ATOM   353   C CA    . GLY A 1 95  ? 124.875 152.037 198.851 1.00 42.81  ? 66  GLY A CA    1 
ATOM   354   C C     . GLY A 1 95  ? 123.480 152.566 199.091 1.00 42.81  ? 66  GLY A C     1 
ATOM   355   O O     . GLY A 1 95  ? 122.542 151.767 199.176 1.00 42.81  ? 66  GLY A O     1 
ATOM   356   N N     . LYS A 1 96  ? 123.313 153.885 199.213 1.00 42.55  ? 67  LYS A N     1 
ATOM   357   C CA    . LYS A 1 96  ? 122.011 154.514 199.388 1.00 42.55  ? 67  LYS A CA    1 
ATOM   358   C C     . LYS A 1 96  ? 121.950 155.783 198.552 1.00 42.55  ? 67  LYS A C     1 
ATOM   359   O O     . LYS A 1 96  ? 122.968 156.298 198.086 1.00 42.55  ? 67  LYS A O     1 
ATOM   360   C CB    . LYS A 1 96  ? 121.722 154.863 200.855 1.00 42.55  ? 67  LYS A CB    1 
ATOM   361   C CG    . LYS A 1 96  ? 121.693 153.685 201.804 1.00 42.55  ? 67  LYS A CG    1 
ATOM   362   C CD    . LYS A 1 96  ? 121.321 154.143 203.207 1.00 42.55  ? 67  LYS A CD    1 
ATOM   363   C CE    . LYS A 1 96  ? 121.560 153.059 204.243 1.00 42.55  ? 67  LYS A CE    1 
ATOM   364   N NZ    . LYS A 1 96  ? 123.009 152.846 204.509 1.00 42.55  ? 67  LYS A NZ    1 
ATOM   365   N N     . ALA A 1 97  ? 120.726 156.270 198.366 1.00 39.62  ? 68  ALA A N     1 
ATOM   366   C CA    . ALA A 1 97  ? 120.452 157.536 197.708 1.00 39.62  ? 68  ALA A CA    1 
ATOM   367   C C     . ALA A 1 97  ? 119.402 158.270 198.523 1.00 39.62  ? 68  ALA A C     1 
ATOM   368   O O     . ALA A 1 97  ? 118.749 157.683 199.388 1.00 39.62  ? 68  ALA A O     1 
ATOM   369   C CB    . ALA A 1 97  ? 119.973 157.332 196.266 1.00 39.62  ? 68  ALA A CB    1 
ATOM   370   N N     . LEU A 1 98  ? 119.259 159.565 198.249 1.00 33.13  ? 69  LEU A N     1 
ATOM   371   C CA    . LEU A 1 98  ? 118.304 160.435 198.919 1.00 33.13  ? 69  LEU A CA    1 
ATOM   372   C C     . LEU A 1 98  ? 117.192 160.803 197.948 1.00 33.13  ? 69  LEU A C     1 
ATOM   373   O O     . LEU A 1 98  ? 117.422 160.902 196.742 1.00 33.13  ? 69  LEU A O     1 
ATOM   374   C CB    . LEU A 1 98  ? 118.999 161.698 199.439 1.00 33.13  ? 69  LEU A CB    1 
ATOM   375   C CG    . LEU A 1 98  ? 118.199 162.713 200.259 1.00 33.13  ? 69  LEU A CG    1 
ATOM   376   C CD1   . LEU A 1 98  ? 117.636 162.100 201.522 1.00 33.13  ? 69  LEU A CD1   1 
ATOM   377   C CD2   . LEU A 1 98  ? 119.067 163.910 200.610 1.00 33.13  ? 69  LEU A CD2   1 
ATOM   378   N N     . LEU A 1 99  ? 115.980 160.970 198.480 1.00 33.40  ? 70  LEU A N     1 
ATOM   379   C CA    . LEU A 1 99  ? 114.815 161.399 197.712 1.00 33.40  ? 70  LEU A CA    1 
ATOM   380   C C     . LEU A 1 99  ? 114.164 162.564 198.436 1.00 33.40  ? 70  LEU A C     1 
ATOM   381   O O     . LEU A 1 99  ? 113.864 162.463 199.629 1.00 33.40  ? 70  LEU A O     1 
ATOM   382   C CB    . LEU A 1 99  ? 113.805 160.256 197.525 1.00 33.40  ? 70  LEU A CB    1 
ATOM   383   C CG    . LEU A 1 99  ? 112.518 160.527 196.725 1.00 33.40  ? 70  LEU A CG    1 
ATOM   384   C CD1   . LEU A 1 99  ? 112.827 160.751 195.256 1.00 33.40  ? 70  LEU A CD1   1 
ATOM   385   C CD2   . LEU A 1 99  ? 111.535 159.383 196.890 1.00 33.40  ? 70  LEU A CD2   1 
ATOM   386   N N     . LEU A 1 100 ? 113.947 163.661 197.711 1.00 29.42  ? 71  LEU A N     1 
ATOM   387   C CA    . LEU A 1 100 ? 113.218 164.830 198.199 1.00 29.42  ? 71  LEU A CA    1 
ATOM   388   C C     . LEU A 1 100 ? 111.855 164.828 197.516 1.00 29.42  ? 71  LEU A C     1 
ATOM   389   O O     . LEU A 1 100 ? 111.730 165.207 196.347 1.00 29.42  ? 71  LEU A O     1 
ATOM   390   C CB    . LEU A 1 100 ? 113.992 166.114 197.921 1.00 29.42  ? 71  LEU A CB    1 
ATOM   391   C CG    . LEU A 1 100 ? 115.423 166.184 198.460 1.00 29.42  ? 71  LEU A CG    1 
ATOM   392   C CD1   . LEU A 1 100 ? 116.074 167.483 198.037 1.00 29.42  ? 71  LEU A CD1   1 
ATOM   393   C CD2   . LEU A 1 100 ? 115.455 166.051 199.971 1.00 29.42  ? 71  LEU A CD2   1 
ATOM   394   N N     . ALA A 1 101 ? 110.840 164.390 198.254 1.00 32.55  ? 72  ALA A N     1 
ATOM   395   C CA    . ALA A 1 101 ? 109.468 164.312 197.773 1.00 32.55  ? 72  ALA A CA    1 
ATOM   396   C C     . ALA A 1 101 ? 108.711 165.536 198.262 1.00 32.55  ? 72  ALA A C     1 
ATOM   397   O O     . ALA A 1 101 ? 108.606 165.757 199.472 1.00 32.55  ? 72  ALA A O     1 
ATOM   398   C CB    . ALA A 1 101 ? 108.798 163.034 198.272 1.00 32.55  ? 72  ALA A CB    1 
ATOM   399   N N     . GLY A 1 102 ? 108.189 166.333 197.332 1.00 34.22  ? 73  GLY A N     1 
ATOM   400   C CA    . GLY A 1 102 ? 107.389 167.468 197.723 1.00 34.22  ? 73  GLY A CA    1 
ATOM   401   C C     . GLY A 1 102 ? 106.840 168.285 196.571 1.00 34.22  ? 73  GLY A C     1 
ATOM   402   O O     . GLY A 1 102 ? 107.137 168.015 195.405 1.00 34.22  ? 73  GLY A O     1 
ATOM   403   N N     . PRO A 1 103 ? 106.027 169.301 196.868 1.00 36.57  ? 74  PRO A N     1 
ATOM   404   C CA    . PRO A 1 103 ? 105.474 170.143 195.799 1.00 36.57  ? 74  PRO A CA    1 
ATOM   405   C C     . PRO A 1 103 ? 106.560 170.951 195.111 1.00 36.57  ? 74  PRO A C     1 
ATOM   406   O O     . PRO A 1 103 ? 107.667 171.087 195.652 1.00 36.57  ? 74  PRO A O     1 
ATOM   407   C CB    . PRO A 1 103 ? 104.499 171.066 196.543 1.00 36.57  ? 74  PRO A CB    1 
ATOM   408   C CG    . PRO A 1 103 ? 104.199 170.385 197.797 1.00 36.57  ? 74  PRO A CG    1 
ATOM   409   C CD    . PRO A 1 103 ? 105.435 169.652 198.174 1.00 36.57  ? 74  PRO A CD    1 
ATOM   410   N N     . PRO A 1 104 ? 106.335 171.479 193.889 1.00 33.36  ? 75  PRO A N     1 
ATOM   411   C CA    . PRO A 1 104 ? 107.315 172.358 193.268 1.00 33.36  ? 75  PRO A CA    1 
ATOM   412   C C     . PRO A 1 104 ? 107.447 173.623 194.101 1.00 33.36  ? 75  PRO A C     1 
ATOM   413   O O     . PRO A 1 104 ? 106.453 174.028 194.738 1.00 33.36  ? 75  PRO A O     1 
ATOM   414   C CB    . PRO A 1 104 ? 106.745 172.625 191.871 1.00 33.36  ? 75  PRO A CB    1 
ATOM   415   C CG    . PRO A 1 104 ? 105.765 171.495 191.652 1.00 33.36  ? 75  PRO A CG    1 
ATOM   416   C CD    . PRO A 1 104 ? 105.198 171.219 193.029 1.00 33.36  ? 75  PRO A CD    1 
ATOM   417   N N     . GLY A 1 105 ? 108.629 174.242 194.099 1.00 30.20  ? 76  GLY A N     1 
ATOM   418   C CA    . GLY A 1 105 ? 108.882 175.475 194.869 1.00 30.20  ? 76  GLY A CA    1 
ATOM   419   C C     . GLY A 1 105 ? 108.690 175.260 196.355 1.00 30.20  ? 76  GLY A C     1 
ATOM   420   O O     . GLY A 1 105 ? 107.964 176.076 196.960 1.00 30.20  ? 76  GLY A O     1 
ATOM   421   N N     . THR A 1 106 ? 109.299 174.217 196.932 1.00 30.48  ? 77  THR A N     1 
ATOM   422   C CA    . THR A 1 106 ? 109.223 173.921 198.383 1.00 30.48  ? 77  THR A CA    1 
ATOM   423   C C     . THR A 1 106 ? 110.603 173.606 198.912 1.00 30.48  ? 77  THR A C     1 
ATOM   424   O O     . THR A 1 106 ? 110.685 172.786 199.835 1.00 30.48  ? 77  THR A O     1 
ATOM   425   C CB    . THR A 1 106 ? 108.249 172.774 198.638 1.00 30.48  ? 77  THR A CB    1 
ATOM   426   O OG1   . THR A 1 106 ? 108.820 171.739 197.850 1.00 30.48  ? 77  THR A OG1   1 
ATOM   427   C CG2   . THR A 1 106 ? 106.826 173.110 198.235 1.00 30.48  ? 77  THR A CG2   1 
ATOM   428   N N     . GLY A 1 107 ? 111.681 174.142 198.333 1.00 29.22  ? 78  GLY A N     1 
ATOM   429   C CA    . GLY A 1 107 ? 113.002 174.011 198.909 1.00 29.22  ? 78  GLY A CA    1 
ATOM   430   C C     . GLY A 1 107 ? 113.864 172.913 198.326 1.00 29.22  ? 78  GLY A C     1 
ATOM   431   O O     . GLY A 1 107 ? 115.089 172.982 198.466 1.00 29.22  ? 78  GLY A O     1 
ATOM   432   N N     . LYS A 1 108 ? 113.258 171.849 197.766 1.00 30.03  ? 79  LYS A N     1 
ATOM   433   C CA    . LYS A 1 108 ? 114.009 170.624 197.343 1.00 30.03  ? 79  LYS A CA    1 
ATOM   434   C C     . LYS A 1 108 ? 115.365 170.939 196.677 1.00 30.03  ? 79  LYS A C     1 
ATOM   435   O O     . LYS A 1 108 ? 116.360 170.455 197.229 1.00 30.03  ? 79  LYS A O     1 
ATOM   436   C CB    . LYS A 1 108 ? 113.262 169.614 196.453 1.00 30.03  ? 79  LYS A CB    1 
ATOM   437   C CG    . LYS A 1 108 ? 112.073 170.045 195.620 1.00 30.03  ? 79  LYS A CG    1 
ATOM   438   C CD    . LYS A 1 108 ? 111.231 168.836 195.225 1.00 30.03  ? 79  LYS A CD    1 
ATOM   439   C CE    . LYS A 1 108 ? 110.146 169.121 194.238 1.00 30.03  ? 79  LYS A CE    1 
ATOM   440   N NZ    . LYS A 1 108 ? 110.682 169.390 192.902 1.00 30.03  ? 79  LYS A NZ    1 
ATOM   441   N N     . THR A 1 109 ? 115.434 171.614 195.524 1.00 31.07  ? 80  THR A N     1 
ATOM   442   C CA    . THR A 1 109 ? 116.731 171.834 194.834 1.00 31.07  ? 80  THR A CA    1 
ATOM   443   C C     . THR A 1 109 ? 117.602 172.656 195.751 1.00 31.07  ? 80  THR A C     1 
ATOM   444   O O     . THR A 1 109 ? 118.833 172.483 195.685 1.00 31.07  ? 80  THR A O     1 
ATOM   445   C CB    . THR A 1 109 ? 116.613 172.543 193.486 1.00 31.07  ? 80  THR A CB    1 
ATOM   446   O OG1   . THR A 1 109 ? 116.127 173.828 193.854 1.00 31.07  ? 80  THR A OG1   1 
ATOM   447   C CG2   . THR A 1 109 ? 115.721 171.825 192.490 1.00 31.07  ? 80  THR A CG2   1 
ATOM   448   N N     . ALA A 1 110 ? 117.004 173.549 196.546 1.00 29.10  ? 81  ALA A N     1 
ATOM   449   C CA    . ALA A 1 110 ? 117.746 174.413 197.493 1.00 29.10  ? 81  ALA A CA    1 
ATOM   450   C C     . ALA A 1 110 ? 118.257 173.573 198.665 1.00 29.10  ? 81  ALA A C     1 
ATOM   451   O O     . ALA A 1 110 ? 119.300 173.970 199.197 1.00 29.10  ? 81  ALA A O     1 
ATOM   452   C CB    . ALA A 1 110 ? 116.867 175.553 197.961 1.00 29.10  ? 81  ALA A CB    1 
ATOM   453   N N     . LEU A 1 111 ? 117.554 172.502 199.064 1.00 28.93  ? 82  LEU A N     1 
ATOM   454   C CA    . LEU A 1 111 ? 117.979 171.610 200.135 1.00 28.93  ? 82  LEU A CA    1 
ATOM   455   C C     . LEU A 1 111 ? 119.185 170.792 199.698 1.00 28.93  ? 82  LEU A C     1 
ATOM   456   O O     . LEU A 1 111 ? 120.117 170.571 200.480 1.00 28.93  ? 82  LEU A O     1 
ATOM   457   C CB    . LEU A 1 111 ? 116.826 170.695 200.540 1.00 28.93  ? 82  LEU A CB    1 
ATOM   458   C CG    . LEU A 1 111 ? 116.828 170.210 201.984 1.00 28.93  ? 82  LEU A CG    1 
ATOM   459   C CD1   . LEU A 1 111 ? 116.201 171.256 202.883 1.00 28.93  ? 82  LEU A CD1   1 
ATOM   460   C CD2   . LEU A 1 111 ? 116.088 168.893 202.093 1.00 28.93  ? 82  LEU A CD2   1 
ATOM   461   N N     . ALA A 1 112 ? 119.183 170.333 198.444 1.00 29.85  ? 83  ALA A N     1 
ATOM   462   C CA    . ALA A 1 112 ? 120.338 169.622 197.907 1.00 29.85  ? 83  ALA A CA    1 
ATOM   463   C C     . ALA A 1 112 ? 121.558 170.528 197.836 1.00 29.85  ? 83  ALA A C     1 
ATOM   464   O O     . ALA A 1 112 ? 122.680 170.096 198.126 1.00 29.85  ? 83  ALA A O     1 
ATOM   465   C CB    . ALA A 1 112 ? 120.010 169.070 196.524 1.00 29.85  ? 83  ALA A CB    1 
ATOM   466   N N     . LEU A 1 113 ? 121.363 171.785 197.435 1.00 29.98  ? 84  LEU A N     1 
ATOM   467   C CA    . LEU A 1 113 ? 122.476 172.726 197.403 1.00 29.98  ? 84  LEU A CA    1 
ATOM   468   C C     . LEU A 1 113 ? 122.996 172.997 198.807 1.00 29.98  ? 84  LEU A C     1 
ATOM   469   O O     . LEU A 1 113 ? 124.203 173.155 199.005 1.00 29.98  ? 84  LEU A O     1 
ATOM   470   C CB    . LEU A 1 113 ? 122.045 174.026 196.722 1.00 29.98  ? 84  LEU A CB    1 
ATOM   471   C CG    . LEU A 1 113 ? 123.103 175.111 196.500 1.00 29.98  ? 84  LEU A CG    1 
ATOM   472   C CD1   . LEU A 1 113 ? 124.214 174.636 195.581 1.00 29.98  ? 84  LEU A CD1   1 
ATOM   473   C CD2   . LEU A 1 113 ? 122.447 176.348 195.933 1.00 29.98  ? 84  LEU A CD2   1 
ATOM   474   N N     . GLY A 1 114 ? 122.102 173.046 199.795 1.00 29.27  ? 85  GLY A N     1 
ATOM   475   C CA    . GLY A 1 114 ? 122.548 173.185 201.171 1.00 29.27  ? 85  GLY A CA    1 
ATOM   476   C C     . GLY A 1 114 ? 123.343 171.984 201.645 1.00 29.27  ? 85  GLY A C     1 
ATOM   477   O O     . GLY A 1 114 ? 124.333 172.130 202.368 1.00 29.27  ? 85  GLY A O     1 
ATOM   478   N N     . ILE A 1 115 ? 122.919 170.782 201.245 1.00 30.36  ? 86  ILE A N     1 
ATOM   479   C CA    . ILE A 1 115 ? 123.656 169.570 201.595 1.00 30.36  ? 86  ILE A CA    1 
ATOM   480   C C     . ILE A 1 115 ? 125.042 169.598 200.963 1.00 30.36  ? 86  ILE A C     1 
ATOM   481   O O     . ILE A 1 115 ? 126.038 169.243 201.602 1.00 30.36  ? 86  ILE A O     1 
ATOM   482   C CB    . ILE A 1 115 ? 122.858 168.318 201.173 1.00 30.36  ? 86  ILE A CB    1 
ATOM   483   C CG1   . ILE A 1 115 ? 121.640 168.124 202.081 1.00 30.36  ? 86  ILE A CG1   1 
ATOM   484   C CG2   . ILE A 1 115 ? 123.728 167.051 201.220 1.00 30.36  ? 86  ILE A CG2   1 
ATOM   485   C CD1   . ILE A 1 115 ? 120.518 167.311 201.460 1.00 30.36  ? 86  ILE A CD1   1 
ATOM   486   N N     . SER A 1 116 ? 125.125 170.014 199.698 1.00 32.38  ? 87  SER A N     1 
ATOM   487   C CA    . SER A 1 116 ? 126.419 170.077 199.025 1.00 32.38  ? 87  SER A CA    1 
ATOM   488   C C     . SER A 1 116 ? 127.319 171.137 199.649 1.00 32.38  ? 87  SER A C     1 
ATOM   489   O O     . SER A 1 116 ? 128.528 170.926 199.792 1.00 32.38  ? 87  SER A O     1 
ATOM   490   C CB    . SER A 1 116 ? 126.225 170.355 197.536 1.00 32.38  ? 87  SER A CB    1 
ATOM   491   O OG    . SER A 1 116 ? 126.171 171.747 197.285 1.00 32.38  ? 87  SER A OG    1 
ATOM   492   N N     . GLN A 1 117 ? 126.749 172.285 200.022 1.00 31.03  ? 88  GLN A N     1 
ATOM   493   C CA    . GLN A 1 117 ? 127.539 173.345 200.639 1.00 31.03  ? 88  GLN A CA    1 
ATOM   494   C C     . GLN A 1 117 ? 128.052 172.928 202.011 1.00 31.03  ? 88  GLN A C     1 
ATOM   495   O O     . GLN A 1 117 ? 129.191 173.243 202.373 1.00 31.03  ? 88  GLN A O     1 
ATOM   496   C CB    . GLN A 1 117 ? 126.704 174.621 200.754 1.00 31.03  ? 88  GLN A CB    1 
ATOM   497   C CG    . GLN A 1 117 ? 126.354 175.280 199.420 1.00 31.03  ? 88  GLN A CG    1 
ATOM   498   C CD    . GLN A 1 117 ? 127.360 176.330 198.978 1.00 31.03  ? 88  GLN A CD    1 
ATOM   499   O OE1   . GLN A 1 117 ? 128.484 176.389 199.477 1.00 31.03  ? 88  GLN A OE1   1 
ATOM   500   N NE2   . GLN A 1 117 ? 126.954 177.168 198.032 1.00 31.03  ? 88  GLN A NE2   1 
ATOM   501   N N     . GLU A 1 118 ? 127.227 172.224 202.790 1.00 34.35  ? 89  GLU A N     1 
ATOM   502   C CA    . GLU A 1 118 ? 127.630 171.858 204.145 1.00 34.35  ? 89  GLU A CA    1 
ATOM   503   C C     . GLU A 1 118 ? 128.765 170.840 204.152 1.00 34.35  ? 89  GLU A C     1 
ATOM   504   O O     . GLU A 1 118 ? 129.537 170.787 205.116 1.00 34.35  ? 89  GLU A O     1 
ATOM   505   C CB    . GLU A 1 118 ? 126.433 171.313 204.922 1.00 34.35  ? 89  GLU A CB    1 
ATOM   506   C CG    . GLU A 1 118 ? 125.549 172.391 205.528 1.00 34.35  ? 89  GLU A CG    1 
ATOM   507   C CD    . GLU A 1 118 ? 126.139 173.006 206.784 1.00 34.35  ? 89  GLU A CD    1 
ATOM   508   O OE1   . GLU A 1 118 ? 126.573 172.249 207.678 1.00 34.35  ? 89  GLU A OE1   1 
ATOM   509   O OE2   . GLU A 1 118 ? 126.170 174.250 206.879 1.00 34.35  ? 89  GLU A OE2   1 
ATOM   510   N N     . LEU A 1 119 ? 128.884 170.022 203.104 1.00 35.51  ? 90  LEU A N     1 
ATOM   511   C CA    . LEU A 1 119 ? 129.977 169.057 203.052 1.00 35.51  ? 90  LEU A CA    1 
ATOM   512   C C     . LEU A 1 119 ? 131.332 169.738 202.888 1.00 35.51  ? 90  LEU A C     1 
ATOM   513   O O     . LEU A 1 119 ? 132.351 169.188 203.322 1.00 35.51  ? 90  LEU A O     1 
ATOM   514   C CB    . LEU A 1 119 ? 129.743 168.064 201.914 1.00 35.51  ? 90  LEU A CB    1 
ATOM   515   C CG    . LEU A 1 119 ? 128.577 167.086 202.088 1.00 35.51  ? 90  LEU A CG    1 
ATOM   516   C CD1   . LEU A 1 119 ? 128.244 166.415 200.765 1.00 35.51  ? 90  LEU A CD1   1 
ATOM   517   C CD2   . LEU A 1 119 ? 128.878 166.038 203.146 1.00 35.51  ? 90  LEU A CD2   1 
ATOM   518   N N     . GLY A 1 120 ? 131.371 170.909 202.278 1.00 42.62  ? 91  GLY A N     1 
ATOM   519   C CA    . GLY A 1 120 ? 132.598 171.664 202.100 1.00 42.62  ? 91  GLY A CA    1 
ATOM   520   C C     . GLY A 1 120 ? 132.462 172.630 200.938 1.00 42.62  ? 91  GLY A C     1 
ATOM   521   O O     . GLY A 1 120 ? 131.659 172.451 200.028 1.00 42.62  ? 91  GLY A O     1 
ATOM   522   N N     . SER A 1 121 ? 133.271 173.692 200.979 1.00 48.90  ? 92  SER A N     1 
ATOM   523   C CA    . SER A 1 121 ? 133.223 174.705 199.927 1.00 48.90  ? 92  SER A CA    1 
ATOM   524   C C     . SER A 1 121 ? 133.676 174.138 198.587 1.00 48.90  ? 92  SER A C     1 
ATOM   525   O O     . SER A 1 121 ? 133.097 174.460 197.543 1.00 48.90  ? 92  SER A O     1 
ATOM   526   C CB    . SER A 1 121 ? 134.087 175.904 200.316 1.00 48.90  ? 92  SER A CB    1 
ATOM   527   O OG    . SER A 1 121 ? 135.463 175.567 200.295 1.00 48.90  ? 92  SER A OG    1 
ATOM   528   N N     . LYS A 1 122 ? 134.706 173.292 198.596 1.00 53.24  ? 93  LYS A N     1 
ATOM   529   C CA    . LYS A 1 122 ? 135.190 172.676 197.367 1.00 53.24  ? 93  LYS A CA    1 
ATOM   530   C C     . LYS A 1 122 ? 134.239 171.624 196.803 1.00 53.24  ? 93  LYS A C     1 
ATOM   531   O O     . LYS A 1 122 ? 134.407 171.232 195.644 1.00 53.24  ? 93  LYS A O     1 
ATOM   532   C CB    . LYS A 1 122 ? 136.557 172.032 197.612 1.00 53.24  ? 93  LYS A CB    1 
ATOM   533   C CG    . LYS A 1 122 ? 137.645 173.009 198.044 1.00 53.24  ? 93  LYS A CG    1 
ATOM   534   C CD    . LYS A 1 122 ? 139.003 172.326 198.232 1.00 53.24  ? 93  LYS A CD    1 
ATOM   535   C CE    . LYS A 1 122 ? 139.093 171.511 199.524 1.00 53.24  ? 93  LYS A CE    1 
ATOM   536   N NZ    . LYS A 1 122 ? 139.035 172.357 200.749 1.00 53.24  ? 93  LYS A NZ    1 
ATOM   537   N N     . VAL A 1 123 ? 133.262 171.162 197.575 1.00 42.99  ? 94  VAL A N     1 
ATOM   538   C CA    . VAL A 1 123 ? 132.450 170.014 197.156 1.00 42.99  ? 94  VAL A CA    1 
ATOM   539   C C     . VAL A 1 123 ? 131.516 170.454 196.026 1.00 42.99  ? 94  VAL A C     1 
ATOM   540   O O     . VAL A 1 123 ? 130.787 171.447 196.198 1.00 42.99  ? 94  VAL A O     1 
ATOM   541   C CB    . VAL A 1 123 ? 131.658 169.458 198.350 1.00 42.99  ? 94  VAL A CB    1 
ATOM   542   C CG1   . VAL A 1 123 ? 130.817 168.251 197.935 1.00 42.99  ? 94  VAL A CG1   1 
ATOM   543   C CG2   . VAL A 1 123 ? 132.601 169.076 199.508 1.00 42.99  ? 94  VAL A CG2   1 
ATOM   544   N N     . PRO A 1 124 ? 131.475 169.777 194.872 1.00 43.60  ? 95  PRO A N     1 
ATOM   545   C CA    . PRO A 1 124 ? 130.666 170.280 193.760 1.00 43.60  ? 95  PRO A CA    1 
ATOM   546   C C     . PRO A 1 124 ? 129.207 169.856 193.880 1.00 43.60  ? 95  PRO A C     1 
ATOM   547   O O     . PRO A 1 124 ? 128.838 169.007 194.691 1.00 43.60  ? 95  PRO A O     1 
ATOM   548   C CB    . PRO A 1 124 ? 131.326 169.635 192.544 1.00 43.60  ? 95  PRO A CB    1 
ATOM   549   C CG    . PRO A 1 124 ? 131.696 168.309 193.039 1.00 43.60  ? 95  PRO A CG    1 
ATOM   550   C CD    . PRO A 1 124 ? 132.089 168.487 194.492 1.00 43.60  ? 95  PRO A CD    1 
ATOM   551   N N     . PHE A 1 125 ? 128.382 170.471 193.032 1.00 34.73  ? 96  PHE A N     1 
ATOM   552   C CA    . PHE A 1 125 ? 126.941 170.230 192.984 1.00 34.73  ? 96  PHE A CA    1 
ATOM   553   C C     . PHE A 1 125 ? 126.532 170.178 191.520 1.00 34.73  ? 96  PHE A C     1 
ATOM   554   O O     . PHE A 1 125 ? 126.610 171.195 190.824 1.00 34.73  ? 96  PHE A O     1 
ATOM   555   C CB    . PHE A 1 125 ? 126.182 171.328 193.731 1.00 34.73  ? 96  PHE A CB    1 
ATOM   556   C CG    . PHE A 1 125 ? 124.689 171.233 193.609 1.00 34.73  ? 96  PHE A CG    1 
ATOM   557   C CD1   . PHE A 1 125 ? 123.984 170.256 194.287 1.00 34.73  ? 96  PHE A CD1   1 
ATOM   558   C CD2   . PHE A 1 125 ? 123.989 172.132 192.826 1.00 34.73  ? 96  PHE A CD2   1 
ATOM   559   C CE1   . PHE A 1 125 ? 122.611 170.172 194.179 1.00 34.73  ? 96  PHE A CE1   1 
ATOM   560   C CE2   . PHE A 1 125 ? 122.617 172.052 192.714 1.00 34.73  ? 96  PHE A CE2   1 
ATOM   561   C CZ    . PHE A 1 125 ? 121.928 171.072 193.392 1.00 34.73  ? 96  PHE A CZ    1 
ATOM   562   N N     . CYS A 1 126 ? 126.088 169.004 191.059 1.00 39.37  ? 97  CYS A N     1 
ATOM   563   C CA    . CYS A 1 126 ? 125.740 168.770 189.659 1.00 39.37  ? 97  CYS A CA    1 
ATOM   564   C C     . CYS A 1 126 ? 124.229 168.593 189.534 1.00 39.37  ? 97  CYS A C     1 
ATOM   565   O O     . CYS A 1 126 ? 123.719 167.491 189.795 1.00 39.37  ? 97  CYS A O     1 
ATOM   566   C CB    . CYS A 1 126 ? 126.465 167.530 189.133 1.00 39.37  ? 97  CYS A CB    1 
ATOM   567   S SG    . CYS A 1 126 ? 128.236 167.776 188.908 1.00 39.37  ? 97  CYS A SG    1 
ATOM   568   N N     . PRO A 1 127 ? 123.466 169.630 189.173 1.00 35.71  ? 98  PRO A N     1 
ATOM   569   C CA    . PRO A 1 127 ? 122.032 169.438 188.932 1.00 35.71  ? 98  PRO A CA    1 
ATOM   570   C C     . PRO A 1 127 ? 121.741 168.961 187.521 1.00 35.71  ? 98  PRO A C     1 
ATOM   571   O O     . PRO A 1 127 ? 122.458 169.267 186.567 1.00 35.71  ? 98  PRO A O     1 
ATOM   572   C CB    . PRO A 1 127 ? 121.446 170.834 189.168 1.00 35.71  ? 98  PRO A CB    1 
ATOM   573   C CG    . PRO A 1 127 ? 122.527 171.750 188.813 1.00 35.71  ? 98  PRO A CG    1 
ATOM   574   C CD    . PRO A 1 127 ? 123.813 171.065 189.168 1.00 35.71  ? 98  PRO A CD    1 
ATOM   575   N N     . MET A 1 128 ? 120.664 168.193 187.407 1.00 41.03  ? 99  MET A N     1 
ATOM   576   C CA    . MET A 1 128 ? 120.165 167.747 186.114 1.00 41.03  ? 99  MET A CA    1 
ATOM   577   C C     . MET A 1 128 ? 118.687 167.424 186.277 1.00 41.03  ? 99  MET A C     1 
ATOM   578   O O     . MET A 1 128 ? 118.170 167.345 187.395 1.00 41.03  ? 99  MET A O     1 
ATOM   579   C CB    . MET A 1 128 ? 120.993 166.560 185.577 1.00 41.03  ? 99  MET A CB    1 
ATOM   580   C CG    . MET A 1 128 ? 120.625 165.133 186.040 1.00 41.03  ? 99  MET A CG    1 
ATOM   581   S SD    . MET A 1 128 ? 121.575 163.899 185.140 1.00 41.03  ? 99  MET A SD    1 
ATOM   582   C CE    . MET A 1 128 ? 120.269 163.082 184.229 1.00 41.03  ? 99  MET A CE    1 
ATOM   583   N N     . VAL A 1 129 ? 118.019 167.235 185.138 1.00 45.83  ? 100 VAL A N     1 
ATOM   584   C CA    . VAL A 1 129 ? 116.611 166.867 185.072 1.00 45.83  ? 100 VAL A CA    1 
ATOM   585   C C     . VAL A 1 129 ? 116.494 165.564 184.293 1.00 45.83  ? 100 VAL A C     1 
ATOM   586   O O     . VAL A 1 129 ? 117.411 165.152 183.579 1.00 45.83  ? 100 VAL A O     1 
ATOM   587   C CB    . VAL A 1 129 ? 115.737 167.974 184.438 1.00 45.83  ? 100 VAL A CB    1 
ATOM   588   C CG1   . VAL A 1 129 ? 115.872 169.263 185.228 1.00 45.83  ? 100 VAL A CG1   1 
ATOM   589   C CG2   . VAL A 1 129 ? 116.086 168.207 182.967 1.00 45.83  ? 100 VAL A CG2   1 
ATOM   590   N N     . GLY A 1 130 ? 115.346 164.902 184.457 1.00 48.11  ? 101 GLY A N     1 
ATOM   591   C CA    . GLY A 1 130 ? 115.127 163.631 183.785 1.00 48.11  ? 101 GLY A CA    1 
ATOM   592   C C     . GLY A 1 130 ? 115.112 163.746 182.275 1.00 48.11  ? 101 GLY A C     1 
ATOM   593   O O     . GLY A 1 130 ? 115.503 162.811 181.573 1.00 48.11  ? 101 GLY A O     1 
ATOM   594   N N     . SER A 1 131 ? 114.655 164.886 181.753 1.00 53.06  ? 102 SER A N     1 
ATOM   595   C CA    . SER A 1 131 ? 114.662 165.101 180.310 1.00 53.06  ? 102 SER A CA    1 
ATOM   596   C C     . SER A 1 131 ? 116.080 165.157 179.754 1.00 53.06  ? 102 SER A C     1 
ATOM   597   O O     . SER A 1 131 ? 116.317 164.727 178.617 1.00 53.06  ? 102 SER A O     1 
ATOM   598   C CB    . SER A 1 131 ? 113.917 166.393 179.977 1.00 53.06  ? 102 SER A CB    1 
ATOM   599   O OG    . SER A 1 131 ? 114.212 166.827 178.662 1.00 53.06  ? 102 SER A OG    1 
ATOM   600   N N     . GLU A 1 132 ? 117.034 165.663 180.546 1.00 50.99  ? 103 GLU A N     1 
ATOM   601   C CA    . GLU A 1 132 ? 118.405 165.876 180.087 1.00 50.99  ? 103 GLU A CA    1 
ATOM   602   C C     . GLU A 1 132 ? 119.095 164.592 179.646 1.00 50.99  ? 103 GLU A C     1 
ATOM   603   O O     . GLU A 1 132 ? 120.022 164.652 178.832 1.00 50.99  ? 103 GLU A O     1 
ATOM   604   C CB    . GLU A 1 132 ? 119.217 166.535 181.204 1.00 50.99  ? 103 GLU A CB    1 
ATOM   605   C CG    . GLU A 1 132 ? 120.650 166.883 180.832 1.00 50.99  ? 103 GLU A CG    1 
ATOM   606   C CD    . GLU A 1 132 ? 121.270 167.888 181.785 1.00 50.99  ? 103 GLU A CD    1 
ATOM   607   O OE1   . GLU A 1 132 ? 120.671 168.965 181.994 1.00 50.99  ? 103 GLU A OE1   1 
ATOM   608   O OE2   . GLU A 1 132 ? 122.357 167.601 182.328 1.00 50.99  ? 103 GLU A OE2   1 
ATOM   609   N N     . VAL A 1 133 ? 118.670 163.435 180.158 1.00 55.20  ? 104 VAL A N     1 
ATOM   610   C CA    . VAL A 1 133 ? 119.274 162.180 179.738 1.00 55.20  ? 104 VAL A CA    1 
ATOM   611   C C     . VAL A 1 133 ? 118.933 161.823 178.294 1.00 55.20  ? 104 VAL A C     1 
ATOM   612   O O     . VAL A 1 133 ? 119.672 161.054 177.668 1.00 55.20  ? 104 VAL A O     1 
ATOM   613   C CB    . VAL A 1 133 ? 118.862 161.054 180.707 1.00 55.20  ? 104 VAL A CB    1 
ATOM   614   C CG1   . VAL A 1 133 ? 117.473 160.483 180.377 1.00 55.20  ? 104 VAL A CG1   1 
ATOM   615   C CG2   . VAL A 1 133 ? 119.916 159.973 180.711 1.00 55.20  ? 104 VAL A CG2   1 
ATOM   616   N N     . TYR A 1 134 ? 117.848 162.371 177.733 1.00 56.62  ? 105 TYR A N     1 
ATOM   617   C CA    . TYR A 1 134 ? 117.366 161.973 176.414 1.00 56.62  ? 105 TYR A CA    1 
ATOM   618   C C     . TYR A 1 134 ? 118.003 162.777 175.280 1.00 56.62  ? 105 TYR A C     1 
ATOM   619   O O     . TYR A 1 134 ? 117.373 162.971 174.237 1.00 56.62  ? 105 TYR A O     1 
ATOM   620   C CB    . TYR A 1 134 ? 115.837 162.083 176.362 1.00 56.62  ? 105 TYR A CB    1 
ATOM   621   C CG    . TYR A 1 134 ? 115.098 161.128 177.275 1.00 56.62  ? 105 TYR A CG    1 
ATOM   622   C CD1   . TYR A 1 134 ? 115.178 159.753 177.089 1.00 56.62  ? 105 TYR A CD1   1 
ATOM   623   C CD2   . TYR A 1 134 ? 114.300 161.601 178.307 1.00 56.62  ? 105 TYR A CD2   1 
ATOM   624   C CE1   . TYR A 1 134 ? 114.501 158.880 177.911 1.00 56.62  ? 105 TYR A CE1   1 
ATOM   625   C CE2   . TYR A 1 134 ? 113.617 160.732 179.134 1.00 56.62  ? 105 TYR A CE2   1 
ATOM   626   C CZ    . TYR A 1 134 ? 113.721 159.374 178.930 1.00 56.62  ? 105 TYR A CZ    1 
ATOM   627   O OH    . TYR A 1 134 ? 113.043 158.505 179.751 1.00 56.62  ? 105 TYR A OH    1 
ATOM   628   N N     . SER A 1 135 ? 119.231 163.260 175.446 1.00 64.79  ? 106 SER A N     1 
ATOM   629   C CA    . SER A 1 135 ? 119.934 163.872 174.326 1.00 64.79  ? 106 SER A CA    1 
ATOM   630   C C     . SER A 1 135 ? 120.219 162.814 173.265 1.00 64.79  ? 106 SER A C     1 
ATOM   631   O O     . SER A 1 135 ? 120.687 161.718 173.580 1.00 64.79  ? 106 SER A O     1 
ATOM   632   C CB    . SER A 1 135 ? 121.234 164.520 174.799 1.00 64.79  ? 106 SER A CB    1 
ATOM   633   O OG    . SER A 1 135 ? 122.272 163.563 174.915 1.00 64.79  ? 106 SER A OG    1 
ATOM   634   N N     . SER A 1 136 ? 119.918 163.137 172.006 1.00 69.03  ? 107 SER A N     1 
ATOM   635   C CA    . SER A 1 136 ? 120.012 162.138 170.944 1.00 69.03  ? 107 SER A CA    1 
ATOM   636   C C     . SER A 1 136 ? 121.461 161.828 170.584 1.00 69.03  ? 107 SER A C     1 
ATOM   637   O O     . SER A 1 136 ? 121.805 160.669 170.324 1.00 69.03  ? 107 SER A O     1 
ATOM   638   C CB    . SER A 1 136 ? 119.253 162.619 169.707 1.00 69.03  ? 107 SER A CB    1 
ATOM   639   O OG    . SER A 1 136 ? 119.810 163.819 169.198 1.00 69.03  ? 107 SER A OG    1 
ATOM   640   N N     . GLU A 1 137 ? 122.316 162.854 170.541 1.00 69.76  ? 108 GLU A N     1 
ATOM   641   C CA    . GLU A 1 137 ? 123.683 162.687 170.048 1.00 69.76  ? 108 GLU A CA    1 
ATOM   642   C C     . GLU A 1 137 ? 124.531 161.750 170.909 1.00 69.76  ? 108 GLU A C     1 
ATOM   643   O O     . GLU A 1 137 ? 125.515 161.200 170.401 1.00 69.76  ? 108 GLU A O     1 
ATOM   644   C CB    . GLU A 1 137 ? 124.418 164.040 169.921 1.00 69.76  ? 108 GLU A CB    1 
ATOM   645   C CG    . GLU A 1 137 ? 124.729 164.877 171.201 1.00 69.76  ? 108 GLU A CG    1 
ATOM   646   C CD    . GLU A 1 137 ? 123.523 165.438 171.928 1.00 69.76  ? 108 GLU A CD    1 
ATOM   647   O OE1   . GLU A 1 137 ? 122.407 165.367 171.372 1.00 69.76  ? 108 GLU A OE1   1 
ATOM   648   O OE2   . GLU A 1 137 ? 123.693 165.952 173.054 1.00 69.76  ? 108 GLU A OE2   1 
ATOM   649   N N     . VAL A 1 138 ? 124.185 161.560 172.186 1.00 67.72  ? 109 VAL A N     1 
ATOM   650   C CA    . VAL A 1 138 ? 124.956 160.749 173.125 1.00 67.72  ? 109 VAL A CA    1 
ATOM   651   C C     . VAL A 1 138 ? 123.987 159.819 173.846 1.00 67.72  ? 109 VAL A C     1 
ATOM   652   O O     . VAL A 1 138 ? 122.850 160.202 174.136 1.00 67.72  ? 109 VAL A O     1 
ATOM   653   C CB    . VAL A 1 138 ? 125.744 161.642 174.116 1.00 67.72  ? 109 VAL A CB    1 
ATOM   654   C CG1   . VAL A 1 138 ? 126.235 160.869 175.335 1.00 67.72  ? 109 VAL A CG1   1 
ATOM   655   C CG2   . VAL A 1 138 ? 126.937 162.281 173.422 1.00 67.72  ? 109 VAL A CG2   1 
ATOM   656   N N     . LYS A 1 139 ? 124.436 158.592 174.118 1.00 67.13  ? 110 LYS A N     1 
ATOM   657   C CA    . LYS A 1 139 ? 123.584 157.583 174.741 1.00 67.13  ? 110 LYS A CA    1 
ATOM   658   C C     . LYS A 1 139 ? 123.149 158.017 176.137 1.00 67.13  ? 110 LYS A C     1 
ATOM   659   O O     . LYS A 1 139 ? 123.878 158.709 176.852 1.00 67.13  ? 110 LYS A O     1 
ATOM   660   C CB    . LYS A 1 139 ? 124.316 156.239 174.828 1.00 67.13  ? 110 LYS A CB    1 
ATOM   661   C CG    . LYS A 1 139 ? 124.129 155.318 173.624 1.00 67.13  ? 110 LYS A CG    1 
ATOM   662   C CD    . LYS A 1 139 ? 122.740 154.690 173.576 1.00 67.13  ? 110 LYS A CD    1 
ATOM   663   C CE    . LYS A 1 139 ? 122.645 153.646 172.473 1.00 67.13  ? 110 LYS A CE    1 
ATOM   664   N NZ    . LYS A 1 139 ? 121.303 153.006 172.415 1.00 67.13  ? 110 LYS A NZ    1 
ATOM   665   N N     . LYS A 1 140 ? 121.935 157.599 176.513 1.00 61.03  ? 111 LYS A N     1 
ATOM   666   C CA    . LYS A 1 140 ? 121.334 158.025 177.778 1.00 61.03  ? 111 LYS A CA    1 
ATOM   667   C C     . LYS A 1 140 ? 122.157 157.567 178.979 1.00 61.03  ? 111 LYS A C     1 
ATOM   668   O O     . LYS A 1 140 ? 122.383 158.342 179.921 1.00 61.03  ? 111 LYS A O     1 
ATOM   669   C CB    . LYS A 1 140 ? 119.894 157.501 177.878 1.00 61.03  ? 111 LYS A CB    1 
ATOM   670   C CG    . LYS A 1 140 ? 119.707 155.977 177.765 1.00 61.03  ? 111 LYS A CG    1 
ATOM   671   C CD    . LYS A 1 140 ? 118.224 155.590 177.647 1.00 61.03  ? 111 LYS A CD    1 
ATOM   672   C CE    . LYS A 1 140 ? 118.013 154.273 176.908 1.00 61.03  ? 111 LYS A CE    1 
ATOM   673   N NZ    . LYS A 1 140 ? 116.581 154.071 176.561 1.00 61.03  ? 111 LYS A NZ    1 
ATOM   674   N N     . THR A 1 141 ? 122.629 156.318 178.953 1.00 59.83  ? 112 THR A N     1 
ATOM   675   C CA    . THR A 1 141 ? 123.501 155.828 180.015 1.00 59.83  ? 112 THR A CA    1 
ATOM   676   C C     . THR A 1 141 ? 124.804 156.613 180.064 1.00 59.83  ? 112 THR A C     1 
ATOM   677   O O     . THR A 1 141 ? 125.354 156.837 181.149 1.00 59.83  ? 112 THR A O     1 
ATOM   678   C CB    . THR A 1 141 ? 123.783 154.339 179.807 1.00 59.83  ? 112 THR A CB    1 
ATOM   679   O OG1   . THR A 1 141 ? 122.561 153.599 179.918 1.00 59.83  ? 112 THR A OG1   1 
ATOM   680   C CG2   . THR A 1 141 ? 124.778 153.820 180.836 1.00 59.83  ? 112 THR A CG2   1 
ATOM   681   N N     . GLU A 1 142 ? 125.302 157.052 178.907 1.00 63.41  ? 113 GLU A N     1 
ATOM   682   C CA    . GLU A 1 142 ? 126.519 157.852 178.890 1.00 63.41  ? 113 GLU A CA    1 
ATOM   683   C C     . GLU A 1 142 ? 126.297 159.218 179.529 1.00 63.41  ? 113 GLU A C     1 
ATOM   684   O O     . GLU A 1 142 ? 127.163 159.700 180.261 1.00 63.41  ? 113 GLU A O     1 
ATOM   685   C CB    . GLU A 1 142 ? 127.029 157.998 177.451 1.00 63.41  ? 113 GLU A CB    1 
ATOM   686   C CG    . GLU A 1 142 ? 128.435 158.616 177.253 1.00 63.41  ? 113 GLU A CG    1 
ATOM   687   C CD    . GLU A 1 142 ? 129.528 158.035 178.141 1.00 63.41  ? 113 GLU A CD    1 
ATOM   688   O OE1   . GLU A 1 142 ? 129.445 156.840 178.495 1.00 63.41  ? 113 GLU A OE1   1 
ATOM   689   O OE2   . GLU A 1 142 ? 130.471 158.778 178.484 1.00 63.41  ? 113 GLU A OE2   1 
ATOM   690   N N     . VAL A 1 143 ? 125.144 159.853 179.278 1.00 60.17  ? 114 VAL A N     1 
ATOM   691   C CA    . VAL A 1 143 ? 124.846 161.134 179.926 1.00 60.17  ? 114 VAL A CA    1 
ATOM   692   C C     . VAL A 1 143 ? 124.721 160.951 181.433 1.00 60.17  ? 114 VAL A C     1 
ATOM   693   O O     . VAL A 1 143 ? 125.214 161.782 182.218 1.00 60.17  ? 114 VAL A O     1 
ATOM   694   C CB    . VAL A 1 143 ? 123.571 161.769 179.332 1.00 60.17  ? 114 VAL A CB    1 
ATOM   695   C CG1   . VAL A 1 143 ? 123.233 163.087 180.065 1.00 60.17  ? 114 VAL A CG1   1 
ATOM   696   C CG2   . VAL A 1 143 ? 123.738 161.999 177.832 1.00 60.17  ? 114 VAL A CG2   1 
ATOM   697   N N     . LEU A 1 144 ? 124.042 159.875 181.857 1.00 55.22  ? 115 LEU A N     1 
ATOM   698   C CA    . LEU A 1 144 ? 123.921 159.574 183.283 1.00 55.22  ? 115 LEU A CA    1 
ATOM   699   C C     . LEU A 1 144 ? 125.285 159.414 183.936 1.00 55.22  ? 115 LEU A C     1 
ATOM   700   O O     . LEU A 1 144 ? 125.574 160.054 184.952 1.00 55.22  ? 115 LEU A O     1 
ATOM   701   C CB    . LEU A 1 144 ? 123.097 158.305 183.506 1.00 55.22  ? 115 LEU A CB    1 
ATOM   702   C CG    . LEU A 1 144 ? 121.587 158.415 183.707 1.00 55.22  ? 115 LEU A CG    1 
ATOM   703   C CD1   . LEU A 1 144 ? 120.977 157.035 183.594 1.00 55.22  ? 115 LEU A CD1   1 
ATOM   704   C CD2   . LEU A 1 144 ? 121.250 159.046 185.055 1.00 55.22  ? 115 LEU A CD2   1 
ATOM   705   N N     . MET A 1 145 ? 126.154 158.595 183.343 1.00 60.95  ? 116 MET A N     1 
ATOM   706   C CA    . MET A 1 145 ? 127.442 158.330 183.967 1.00 60.95  ? 116 MET A CA    1 
ATOM   707   C C     . MET A 1 145 ? 128.361 159.544 183.862 1.00 60.95  ? 116 MET A C     1 
ATOM   708   O O     . MET A 1 145 ? 129.230 159.733 184.717 1.00 60.95  ? 116 MET A O     1 
ATOM   709   C CB    . MET A 1 145 ? 128.094 157.112 183.311 1.00 60.95  ? 116 MET A CB    1 
ATOM   710   C CG    . MET A 1 145 ? 129.319 156.507 184.025 1.00 60.95  ? 116 MET A CG    1 
ATOM   711   S SD    . MET A 1 145 ? 129.024 156.015 185.752 1.00 60.95  ? 116 MET A SD    1 
ATOM   712   C CE    . MET A 1 145 ? 130.539 156.443 186.597 1.00 60.95  ? 116 MET A CE    1 
ATOM   713   N N     . GLU A 1 146 ? 128.182 160.381 182.831 1.00 61.91  ? 117 GLU A N     1 
ATOM   714   C CA    . GLU A 1 146 ? 128.935 161.627 182.737 1.00 61.91  ? 117 GLU A CA    1 
ATOM   715   C C     . GLU A 1 146 ? 128.593 162.558 183.890 1.00 61.91  ? 117 GLU A C     1 
ATOM   716   O O     . GLU A 1 146 ? 129.486 163.132 184.517 1.00 61.91  ? 117 GLU A O     1 
ATOM   717   C CB    . GLU A 1 146 ? 128.656 162.313 181.397 1.00 61.91  ? 117 GLU A CB    1 
ATOM   718   C CG    . GLU A 1 146 ? 129.646 163.407 181.014 1.00 61.91  ? 117 GLU A CG    1 
ATOM   719   C CD    . GLU A 1 146 ? 129.012 164.478 180.152 1.00 61.91  ? 117 GLU A CD    1 
ATOM   720   O OE1   . GLU A 1 146 ? 128.544 164.147 179.043 1.00 61.91  ? 117 GLU A OE1   1 
ATOM   721   O OE2   . GLU A 1 146 ? 128.985 165.651 180.581 1.00 61.91  ? 117 GLU A OE2   1 
ATOM   722   N N     . ASN A 1 147 ? 127.301 162.723 184.185 1.00 54.87  ? 118 ASN A N     1 
ATOM   723   C CA    . ASN A 1 147 ? 126.930 163.536 185.344 1.00 54.87  ? 118 ASN A CA    1 
ATOM   724   C C     . ASN A 1 147 ? 127.373 162.872 186.645 1.00 54.87  ? 118 ASN A C     1 
ATOM   725   O O     . ASN A 1 147 ? 127.781 163.555 187.597 1.00 54.87  ? 118 ASN A O     1 
ATOM   726   C CB    . ASN A 1 147 ? 125.425 163.787 185.347 1.00 54.87  ? 118 ASN A CB    1 
ATOM   727   C CG    . ASN A 1 147 ? 124.991 164.709 184.230 1.00 54.87  ? 118 ASN A CG    1 
ATOM   728   O OD1   . ASN A 1 147 ? 125.088 165.930 184.347 1.00 54.87  ? 118 ASN A OD1   1 
ATOM   729   N ND2   . ASN A 1 147 ? 124.508 164.131 183.138 1.00 54.87  ? 118 ASN A ND2   1 
ATOM   730   N N     . PHE A 1 148 ? 127.318 161.537 186.681 1.00 53.18  ? 119 PHE A N     1 
ATOM   731   C CA    . PHE A 1 148 ? 127.748 160.759 187.838 1.00 53.18  ? 119 PHE A CA    1 
ATOM   732   C C     . PHE A 1 148 ? 129.214 161.020 188.159 1.00 53.18  ? 119 PHE A C     1 
ATOM   733   O O     . PHE A 1 148 ? 129.582 161.197 189.325 1.00 53.18  ? 119 PHE A O     1 
ATOM   734   C CB    . PHE A 1 148 ? 127.512 159.279 187.532 1.00 53.18  ? 119 PHE A CB    1 
ATOM   735   C CG    . PHE A 1 148 ? 127.420 158.387 188.730 1.00 53.18  ? 119 PHE A CG    1 
ATOM   736   C CD1   . PHE A 1 148 ? 128.555 157.863 189.321 1.00 53.18  ? 119 PHE A CD1   1 
ATOM   737   C CD2   . PHE A 1 148 ? 126.182 158.008 189.216 1.00 53.18  ? 119 PHE A CD2   1 
ATOM   738   C CE1   . PHE A 1 148 ? 128.454 157.011 190.404 1.00 53.18  ? 119 PHE A CE1   1 
ATOM   739   C CE2   . PHE A 1 148 ? 126.075 157.159 190.296 1.00 53.18  ? 119 PHE A CE2   1 
ATOM   740   C CZ    . PHE A 1 148 ? 127.211 156.655 190.886 1.00 53.18  ? 119 PHE A CZ    1 
ATOM   741   N N     . ARG A 1 149 ? 130.061 161.064 187.128 1.00 61.67  ? 120 ARG A N     1 
ATOM   742   C CA    . ARG A 1 149 ? 131.481 161.332 187.310 1.00 61.67  ? 120 ARG A CA    1 
ATOM   743   C C     . ARG A 1 149 ? 131.778 162.818 187.455 1.00 61.67  ? 120 ARG A C     1 
ATOM   744   O O     . ARG A 1 149 ? 132.794 163.175 188.061 1.00 61.67  ? 120 ARG A O     1 
ATOM   745   C CB    . ARG A 1 149 ? 132.278 160.753 186.136 1.00 61.67  ? 120 ARG A CB    1 
ATOM   746   C CG    . ARG A 1 149 ? 132.332 159.239 186.157 1.00 61.67  ? 120 ARG A CG    1 
ATOM   747   C CD    . ARG A 1 149 ? 133.406 158.631 185.273 1.00 61.67  ? 120 ARG A CD    1 
ATOM   748   N NE    . ARG A 1 149 ? 133.011 158.612 183.869 1.00 61.67  ? 120 ARG A NE    1 
ATOM   749   C CZ    . ARG A 1 149 ? 133.793 158.259 182.856 1.00 61.67  ? 120 ARG A CZ    1 
ATOM   750   N NH1   . ARG A 1 149 ? 135.037 157.836 183.041 1.00 61.67  ? 120 ARG A NH1   1 
ATOM   751   N NH2   . ARG A 1 149 ? 133.309 158.312 181.619 1.00 61.67  ? 120 ARG A NH2   1 
ATOM   752   N N     . ARG A 1 150 ? 130.923 163.690 186.915 1.00 54.60  ? 121 ARG A N     1 
ATOM   753   C CA    . ARG A 1 150 ? 131.078 165.121 187.144 1.00 54.60  ? 121 ARG A CA    1 
ATOM   754   C C     . ARG A 1 150 ? 130.871 165.452 188.614 1.00 54.60  ? 121 ARG A C     1 
ATOM   755   O O     . ARG A 1 150 ? 131.551 166.327 189.162 1.00 54.60  ? 121 ARG A O     1 
ATOM   756   C CB    . ARG A 1 150 ? 130.094 165.898 186.264 1.00 54.60  ? 121 ARG A CB    1 
ATOM   757   C CG    . ARG A 1 150 ? 130.304 167.426 186.202 1.00 54.60  ? 121 ARG A CG    1 
ATOM   758   C CD    . ARG A 1 150 ? 131.227 167.852 185.067 1.00 54.60  ? 121 ARG A CD    1 
ATOM   759   N NE    . ARG A 1 150 ? 130.637 167.619 183.752 1.00 54.60  ? 121 ARG A NE    1 
ATOM   760   C CZ    . ARG A 1 150 ? 129.637 168.311 183.218 1.00 54.60  ? 121 ARG A CZ    1 
ATOM   761   N NH1   . ARG A 1 150 ? 129.083 169.343 183.842 1.00 54.60  ? 121 ARG A NH1   1 
ATOM   762   N NH2   . ARG A 1 150 ? 129.179 167.963 182.020 1.00 54.60  ? 121 ARG A NH2   1 
ATOM   763   N N     . ALA A 1 151 ? 129.934 164.762 189.267 1.00 47.78  ? 122 ALA A N     1 
ATOM   764   C CA    . ALA A 1 151 ? 129.699 165.006 190.686 1.00 47.78  ? 122 ALA A CA    1 
ATOM   765   C C     . ALA A 1 151 ? 130.889 164.594 191.545 1.00 47.78  ? 122 ALA A C     1 
ATOM   766   O O     . ALA A 1 151 ? 131.162 165.237 192.563 1.00 47.78  ? 122 ALA A O     1 
ATOM   767   C CB    . ALA A 1 151 ? 128.441 164.270 191.138 1.00 47.78  ? 122 ALA A CB    1 
ATOM   768   N N     . ILE A 1 152 ? 131.610 163.544 191.161 1.00 56.68  ? 123 ILE A N     1 
ATOM   769   C CA    . ILE A 1 152 ? 132.685 163.023 192.001 1.00 56.68  ? 123 ILE A CA    1 
ATOM   770   C C     . ILE A 1 152 ? 133.855 163.998 191.958 1.00 56.68  ? 123 ILE A C     1 
ATOM   771   O O     . ILE A 1 152 ? 134.463 164.203 190.901 1.00 56.68  ? 123 ILE A O     1 
ATOM   772   C CB    . ILE A 1 152 ? 133.118 161.620 191.549 1.00 56.68  ? 123 ILE A CB    1 
ATOM   773   C CG1   . ILE A 1 152 ? 131.970 160.601 191.685 1.00 56.68  ? 123 ILE A CG1   1 
ATOM   774   C CG2   . ILE A 1 152 ? 134.340 161.162 192.361 1.00 56.68  ? 123 ILE A CG2   1 
ATOM   775   C CD1   . ILE A 1 152 ? 132.168 159.320 190.884 1.00 56.68  ? 123 ILE A CD1   1 
ATOM   776   N N     . GLY A 1 153 ? 134.179 164.589 193.108 1.00 57.89  ? 124 GLY A N     1 
ATOM   777   C CA    . GLY A 1 153 ? 135.264 165.547 193.219 1.00 57.89  ? 124 GLY A CA    1 
ATOM   778   C C     . GLY A 1 153 ? 136.513 164.924 193.813 1.00 57.89  ? 124 GLY A C     1 
ATOM   779   O O     . GLY A 1 153 ? 136.437 164.018 194.637 1.00 57.89  ? 124 GLY A O     1 
ATOM   780   N N     . LEU A 1 154 ? 137.670 165.449 193.413 1.00 67.39  ? 125 LEU A N     1 
ATOM   781   C CA    . LEU A 1 154 ? 138.956 165.037 193.953 1.00 67.39  ? 125 LEU A CA    1 
ATOM   782   C C     . LEU A 1 154 ? 139.862 166.255 193.998 1.00 67.39  ? 125 LEU A C     1 
ATOM   783   O O     . LEU A 1 154 ? 139.685 167.202 193.225 1.00 67.39  ? 125 LEU A O     1 
ATOM   784   C CB    . LEU A 1 154 ? 139.623 163.942 193.108 1.00 67.39  ? 125 LEU A CB    1 
ATOM   785   C CG    . LEU A 1 154 ? 138.793 162.741 192.649 1.00 67.39  ? 125 LEU A CG    1 
ATOM   786   C CD1   . LEU A 1 154 ? 138.244 162.974 191.252 1.00 67.39  ? 125 LEU A CD1   1 
ATOM   787   C CD2   . LEU A 1 154 ? 139.627 161.473 192.689 1.00 67.39  ? 125 LEU A CD2   1 
ATOM   788   N N     . ARG A 1 155 ? 140.828 166.224 194.916 1.00 74.67  ? 126 ARG A N     1 
ATOM   789   C CA    . ARG A 1 155 ? 141.904 167.206 194.967 1.00 74.67  ? 126 ARG A CA    1 
ATOM   790   C C     . ARG A 1 155 ? 143.230 166.466 195.040 1.00 74.67  ? 126 ARG A C     1 
ATOM   791   O O     . ARG A 1 155 ? 143.391 165.555 195.859 1.00 74.67  ? 126 ARG A O     1 
ATOM   792   C CB    . ARG A 1 155 ? 141.729 168.185 196.147 1.00 74.67  ? 126 ARG A CB    1 
ATOM   793   C CG    . ARG A 1 155 ? 141.888 167.624 197.575 1.00 74.67  ? 126 ARG A CG    1 
ATOM   794   C CD    . ARG A 1 155 ? 141.913 168.737 198.620 1.00 74.67  ? 126 ARG A CD    1 
ATOM   795   N NE    . ARG A 1 155 ? 142.445 168.256 199.894 1.00 74.67  ? 126 ARG A NE    1 
ATOM   796   C CZ    . ARG A 1 155 ? 143.068 168.990 200.814 1.00 74.67  ? 126 ARG A CZ    1 
ATOM   797   N NH1   . ARG A 1 155 ? 143.232 170.300 200.683 1.00 74.67  ? 126 ARG A NH1   1 
ATOM   798   N NH2   . ARG A 1 155 ? 143.535 168.392 201.906 1.00 74.67  ? 126 ARG A NH2   1 
ATOM   799   N N     . ILE A 1 156 ? 144.165 166.854 194.175 1.00 79.80  ? 127 ILE A N     1 
ATOM   800   C CA    . ILE A 1 156 ? 145.500 166.269 194.100 1.00 79.80  ? 127 ILE A CA    1 
ATOM   801   C C     . ILE A 1 156 ? 146.466 167.292 194.678 1.00 79.80  ? 127 ILE A C     1 
ATOM   802   O O     . ILE A 1 156 ? 146.502 168.444 194.225 1.00 79.80  ? 127 ILE A O     1 
ATOM   803   C CB    . ILE A 1 156 ? 145.881 165.892 192.657 1.00 79.80  ? 127 ILE A CB    1 
ATOM   804   C CG1   . ILE A 1 156 ? 144.977 164.772 192.114 1.00 79.80  ? 127 ILE A CG1   1 
ATOM   805   C CG2   . ILE A 1 156 ? 147.345 165.455 192.590 1.00 79.80  ? 127 ILE A CG2   1 
ATOM   806   C CD1   . ILE A 1 156 ? 144.903 164.717 190.598 1.00 79.80  ? 127 ILE A CD1   1 
ATOM   807   N N     . LYS A 1 157 ? 147.244 166.865 195.672 1.00 81.23  ? 128 LYS A N     1 
ATOM   808   C CA    . LYS A 1 157 ? 148.180 167.727 196.401 1.00 81.23  ? 128 LYS A CA    1 
ATOM   809   C C     . LYS A 1 157 ? 149.613 167.252 196.186 1.00 81.23  ? 128 LYS A C     1 
ATOM   810   O O     . LYS A 1 157 ? 149.861 166.066 195.967 1.00 81.23  ? 128 LYS A O     1 
ATOM   811   C CB    . LYS A 1 157 ? 147.849 167.749 197.899 1.00 81.23  ? 128 LYS A CB    1 
ATOM   812   C CG    . LYS A 1 157 ? 147.617 166.374 198.530 1.00 81.23  ? 128 LYS A CG    1 
ATOM   813   C CD    . LYS A 1 157 ? 147.668 166.409 200.057 1.00 81.23  ? 128 LYS A CD    1 
ATOM   814   C CE    . LYS A 1 157 ? 146.493 167.166 200.666 1.00 81.23  ? 128 LYS A CE    1 
ATOM   815   N NZ    . LYS A 1 157 ? 146.567 167.182 202.153 1.00 81.23  ? 128 LYS A NZ    1 
ATOM   816   N N     . VAL A 1 267 ? 147.224 173.066 195.383 1.00 77.75  ? 238 VAL A N     1 
ATOM   817   C CA    . VAL A 1 267 ? 146.407 171.873 195.210 1.00 77.75  ? 238 VAL A CA    1 
ATOM   818   C C     . VAL A 1 267 ? 145.531 172.033 193.971 1.00 77.75  ? 238 VAL A C     1 
ATOM   819   O O     . VAL A 1 267 ? 145.045 173.129 193.686 1.00 77.75  ? 238 VAL A O     1 
ATOM   820   C CB    . VAL A 1 267 ? 145.561 171.593 196.473 1.00 77.75  ? 238 VAL A CB    1 
ATOM   821   C CG1   . VAL A 1 267 ? 144.417 172.597 196.610 1.00 77.75  ? 238 VAL A CG1   1 
ATOM   822   C CG2   . VAL A 1 267 ? 145.038 170.163 196.463 1.00 77.75  ? 238 VAL A CG2   1 
ATOM   823   N N     . GLN A 1 268 ? 145.335 170.928 193.250 1.00 76.26  ? 239 GLN A N     1 
ATOM   824   C CA    . GLN A 1 268 ? 144.643 170.904 191.962 1.00 76.26  ? 239 GLN A CA    1 
ATOM   825   C C     . GLN A 1 268 ? 143.318 170.168 192.142 1.00 76.26  ? 239 GLN A C     1 
ATOM   826   O O     . GLN A 1 268 ? 143.307 168.964 192.413 1.00 76.26  ? 239 GLN A O     1 
ATOM   827   C CB    . GLN A 1 268 ? 145.537 170.246 190.907 1.00 76.26  ? 239 GLN A CB    1 
ATOM   828   C CG    . GLN A 1 268 ? 144.838 169.474 189.790 1.00 76.26  ? 239 GLN A CG    1 
ATOM   829   C CD    . GLN A 1 268 ? 145.767 169.171 188.630 1.00 76.26  ? 239 GLN A CD    1 
ATOM   830   O OE1   . GLN A 1 268 ? 146.987 169.282 188.751 1.00 76.26  ? 239 GLN A OE1   1 
ATOM   831   N NE2   . GLN A 1 268 ? 145.192 168.786 187.496 1.00 76.26  ? 239 GLN A NE2   1 
ATOM   832   N N     . ASP A 1 269 ? 142.210 170.893 191.977 1.00 71.74  ? 240 ASP A N     1 
ATOM   833   C CA    . ASP A 1 269 ? 140.867 170.344 192.146 1.00 71.74  ? 240 ASP A CA    1 
ATOM   834   C C     . ASP A 1 269 ? 140.335 169.884 190.794 1.00 71.74  ? 240 ASP A C     1 
ATOM   835   O O     . ASP A 1 269 ? 140.228 170.688 189.861 1.00 71.74  ? 240 ASP A O     1 
ATOM   836   C CB    . ASP A 1 269 ? 139.935 171.390 192.754 1.00 71.74  ? 240 ASP A CB    1 
ATOM   837   C CG    . ASP A 1 269 ? 140.468 171.963 194.050 1.00 71.74  ? 240 ASP A CG    1 
ATOM   838   O OD1   . ASP A 1 269 ? 141.099 171.208 194.819 1.00 71.74  ? 240 ASP A OD1   1 
ATOM   839   O OD2   . ASP A 1 269 ? 140.256 173.168 194.299 1.00 71.74  ? 240 ASP A OD2   1 
ATOM   840   N N     . VAL A 1 270 ? 140.004 168.594 190.693 1.00 69.09  ? 241 VAL A N     1 
ATOM   841   C CA    . VAL A 1 270 ? 139.552 167.962 189.455 1.00 69.09  ? 241 VAL A CA    1 
ATOM   842   C C     . VAL A 1 270 ? 138.350 167.075 189.756 1.00 69.09  ? 241 VAL A C     1 
ATOM   843   O O     . VAL A 1 270 ? 138.300 166.412 190.795 1.00 69.09  ? 241 VAL A O     1 
ATOM   844   C CB    . VAL A 1 270 ? 140.685 167.148 188.775 1.00 69.09  ? 241 VAL A CB    1 
ATOM   845   C CG1   . VAL A 1 270 ? 141.993 167.904 188.791 1.00 69.09  ? 241 VAL A CG1   1 
ATOM   846   C CG2   . VAL A 1 270 ? 140.920 165.808 189.484 1.00 69.09  ? 241 VAL A CG2   1 
ATOM   847   N N     . THR A 1 271 ? 137.381 167.070 188.845 1.00 63.05  ? 242 THR A N     1 
ATOM   848   C CA    . THR A 1 271 ? 136.314 166.082 188.877 1.00 63.05  ? 242 THR A CA    1 
ATOM   849   C C     . THR A 1 271 ? 136.772 164.810 188.170 1.00 63.05  ? 242 THR A C     1 
ATOM   850   O O     . THR A 1 271 ? 137.769 164.797 187.444 1.00 63.05  ? 242 THR A O     1 
ATOM   851   C CB    . THR A 1 271 ? 135.048 166.616 188.209 1.00 63.05  ? 242 THR A CB    1 
ATOM   852   O OG1   . THR A 1 271 ? 135.234 166.650 186.790 1.00 63.05  ? 242 THR A OG1   1 
ATOM   853   C CG2   . THR A 1 271 ? 134.717 168.014 188.714 1.00 63.05  ? 242 THR A CG2   1 
ATOM   854   N N     . LEU A 1 272 ? 136.025 163.727 188.390 1.00 61.74  ? 243 LEU A N     1 
ATOM   855   C CA    . LEU A 1 272 ? 136.325 162.479 187.698 1.00 61.74  ? 243 LEU A CA    1 
ATOM   856   C C     . LEU A 1 272 ? 135.953 162.528 186.220 1.00 61.74  ? 243 LEU A C     1 
ATOM   857   O O     . LEU A 1 272 ? 136.410 161.673 185.456 1.00 61.74  ? 243 LEU A O     1 
ATOM   858   C CB    . LEU A 1 272 ? 135.608 161.308 188.372 1.00 61.74  ? 243 LEU A CB    1 
ATOM   859   C CG    . LEU A 1 272 ? 136.372 159.981 188.350 1.00 61.74  ? 243 LEU A CG    1 
ATOM   860   C CD1   . LEU A 1 272 ? 137.430 159.950 189.439 1.00 61.74  ? 243 LEU A CD1   1 
ATOM   861   C CD2   . LEU A 1 272 ? 135.427 158.800 188.493 1.00 61.74  ? 243 LEU A CD2   1 
ATOM   862   N N     . GLN A 1 273 ? 135.133 163.498 185.799 1.00 61.05  ? 244 GLN A N     1 
ATOM   863   C CA    . GLN A 1 273 ? 134.839 163.653 184.379 1.00 61.05  ? 244 GLN A CA    1 
ATOM   864   C C     . GLN A 1 273 ? 136.031 164.238 183.631 1.00 61.05  ? 244 GLN A C     1 
ATOM   865   O O     . GLN A 1 273 ? 136.333 163.815 182.509 1.00 61.05  ? 244 GLN A O     1 
ATOM   866   C CB    . GLN A 1 273 ? 133.599 164.535 184.202 1.00 61.05  ? 244 GLN A CB    1 
ATOM   867   C CG    . GLN A 1 273 ? 133.176 164.834 182.753 1.00 61.05  ? 244 GLN A CG    1 
ATOM   868   C CD    . GLN A 1 273 ? 133.009 163.593 181.885 1.00 61.05  ? 244 GLN A CD    1 
ATOM   869   O OE1   . GLN A 1 273 ? 133.450 163.571 180.737 1.00 61.05  ? 244 GLN A OE1   1 
ATOM   870   N NE2   . GLN A 1 273 ? 132.368 162.561 182.426 1.00 61.05  ? 244 GLN A NE2   1 
ATOM   871   N N     . ASP A 1 274 ? 136.717 165.215 184.233 1.00 65.28  ? 245 ASP A N     1 
ATOM   872   C CA    . ASP A 1 274 ? 137.874 165.821 183.580 1.00 65.28  ? 245 ASP A CA    1 
ATOM   873   C C     . ASP A 1 274 ? 139.011 164.819 183.419 1.00 65.28  ? 245 ASP A C     1 
ATOM   874   O O     . ASP A 1 274 ? 139.732 164.849 182.415 1.00 65.28  ? 245 ASP A O     1 
ATOM   875   C CB    . ASP A 1 274 ? 138.349 167.041 184.370 1.00 65.28  ? 245 ASP A CB    1 
ATOM   876   C CG    . ASP A 1 274 ? 137.268 168.092 184.528 1.00 65.28  ? 245 ASP A CG    1 
ATOM   877   O OD1   . ASP A 1 274 ? 136.664 168.485 183.508 1.00 65.28  ? 245 ASP A OD1   1 
ATOM   878   O OD2   . ASP A 1 274 ? 137.023 168.527 185.673 1.00 65.28  ? 245 ASP A OD2   1 
ATOM   879   N N     . LEU A 1 275 ? 139.194 163.931 184.399 1.00 67.09  ? 246 LEU A N     1 
ATOM   880   C CA    . LEU A 1 275 ? 140.232 162.910 184.278 1.00 67.09  ? 246 LEU A CA    1 
ATOM   881   C C     . LEU A 1 275 ? 139.920 161.920 183.164 1.00 67.09  ? 246 LEU A C     1 
ATOM   882   O O     . LEU A 1 275 ? 140.844 161.360 182.565 1.00 67.09  ? 246 LEU A O     1 
ATOM   883   C CB    . LEU A 1 275 ? 140.422 162.162 185.601 1.00 67.09  ? 246 LEU A CB    1 
ATOM   884   C CG    . LEU A 1 275 ? 141.687 162.531 186.374 1.00 67.09  ? 246 LEU A CG    1 
ATOM   885   C CD1   . LEU A 1 275 ? 141.676 163.998 186.744 1.00 67.09  ? 246 LEU A CD1   1 
ATOM   886   C CD2   . LEU A 1 275 ? 141.817 161.672 187.623 1.00 67.09  ? 246 LEU A CD2   1 
ATOM   887   N N     . ASP A 1 276 ? 138.638 161.691 182.873 1.00 66.86  ? 247 ASP A N     1 
ATOM   888   C CA    . ASP A 1 276 ? 138.280 160.876 181.718 1.00 66.86  ? 247 ASP A CA    1 
ATOM   889   C C     . ASP A 1 276 ? 138.443 161.653 180.419 1.00 66.86  ? 247 ASP A C     1 
ATOM   890   O O     . ASP A 1 276 ? 138.836 161.078 179.398 1.00 66.86  ? 247 ASP A O     1 
ATOM   891   C CB    . ASP A 1 276 ? 136.846 160.373 181.848 1.00 66.86  ? 247 ASP A CB    1 
ATOM   892   C CG    . ASP A 1 276 ? 136.429 159.498 180.678 1.00 66.86  ? 247 ASP A CG    1 
ATOM   893   O OD1   . ASP A 1 276 ? 136.013 160.046 179.636 1.00 66.86  ? 247 ASP A OD1   1 
ATOM   894   O OD2   . ASP A 1 276 ? 136.526 158.260 180.799 1.00 66.86  ? 247 ASP A OD2   1 
ATOM   895   N N     . ALA A 1 277 ? 138.132 162.952 180.436 1.00 66.01  ? 248 ALA A N     1 
ATOM   896   C CA    . ALA A 1 277 ? 138.272 163.763 179.230 1.00 66.01  ? 248 ALA A CA    1 
ATOM   897   C C     . ALA A 1 277 ? 139.731 163.875 178.808 1.00 66.01  ? 248 ALA A C     1 
ATOM   898   O O     . ALA A 1 277 ? 140.053 163.763 177.619 1.00 66.01  ? 248 ALA A O     1 
ATOM   899   C CB    . ALA A 1 277 ? 137.673 165.150 179.461 1.00 66.01  ? 248 ALA A CB    1 
ATOM   900   N N     . ALA A 1 278 ? 140.630 164.088 179.771 1.00 67.39  ? 249 ALA A N     1 
ATOM   901   C CA    . ALA A 1 278 ? 142.054 164.141 179.468 1.00 67.39  ? 249 ALA A CA    1 
ATOM   902   C C     . ALA A 1 278 ? 142.622 162.786 179.057 1.00 67.39  ? 249 ALA A C     1 
ATOM   903   O O     . ALA A 1 278 ? 143.676 162.752 178.412 1.00 67.39  ? 249 ALA A O     1 
ATOM   904   C CB    . ALA A 1 278 ? 142.825 164.674 180.675 1.00 67.39  ? 249 ALA A CB    1 
ATOM   905   N N     . ASN A 1 279 ? 141.958 161.681 179.411 1.00 67.18  ? 250 ASN A N     1 
ATOM   906   C CA    . ASN A 1 279 ? 142.394 160.318 179.116 1.00 67.18  ? 250 ASN A CA    1 
ATOM   907   C C     . ASN A 1 279 ? 141.296 159.549 178.395 1.00 67.18  ? 250 ASN A C     1 
ATOM   908   O O     . ASN A 1 279 ? 141.093 158.354 178.627 1.00 67.18  ? 250 ASN A O     1 
ATOM   909   C CB    . ASN A 1 279 ? 142.802 159.595 180.396 1.00 67.18  ? 250 ASN A CB    1 
ATOM   910   C CG    . ASN A 1 279 ? 143.908 160.316 181.144 1.00 67.18  ? 250 ASN A CG    1 
ATOM   911   O OD1   . ASN A 1 279 ? 143.724 161.441 181.607 1.00 67.18  ? 250 ASN A OD1   1 
ATOM   912   N ND2   . ASN A 1 279 ? 145.063 159.671 181.268 1.00 67.18  ? 250 ASN A ND2   1 
ATOM   913   N N     . ALA A 1 280 ? 140.571 160.223 177.507 1.00 69.54  ? 251 ALA A N     1 
ATOM   914   C CA    . ALA A 1 280 ? 139.492 159.590 176.756 1.00 69.54  ? 251 ALA A CA    1 
ATOM   915   C C     . ALA A 1 280 ? 140.050 158.721 175.635 1.00 69.54  ? 251 ALA A C     1 
ATOM   916   O O     . ALA A 1 280 ? 141.012 159.094 174.965 1.00 69.54  ? 251 ALA A O     1 
ATOM   917   C CB    . ALA A 1 280 ? 138.553 160.642 176.190 1.00 69.54  ? 251 ALA A CB    1 
ATOM   918   N N     . LYS A 1 306 ? 134.517 155.807 177.956 1.00 76.52  ? 277 LYS A N     1 
ATOM   919   C CA    . LYS A 1 306 ? 134.891 154.405 178.089 1.00 76.52  ? 277 LYS A CA    1 
ATOM   920   C C     . LYS A 1 306 ? 136.272 154.304 178.738 1.00 76.52  ? 277 LYS A C     1 
ATOM   921   O O     . LYS A 1 306 ? 136.854 155.322 179.112 1.00 76.52  ? 277 LYS A O     1 
ATOM   922   C CB    . LYS A 1 306 ? 134.864 153.720 176.706 1.00 76.52  ? 277 LYS A CB    1 
ATOM   923   C CG    . LYS A 1 306 ? 134.455 152.220 176.625 1.00 76.52  ? 277 LYS A CG    1 
ATOM   924   C CD    . LYS A 1 306 ? 133.185 151.816 177.394 1.00 76.52  ? 277 LYS A CD    1 
ATOM   925   C CE    . LYS A 1 306 ? 132.015 152.757 177.144 1.00 76.52  ? 277 LYS A CE    1 
ATOM   926   N NZ    . LYS A 1 306 ? 130.742 152.193 177.666 1.00 76.52  ? 277 LYS A NZ    1 
ATOM   927   N N     . LEU A 1 307 ? 136.776 153.074 178.889 1.00 78.44  ? 278 LEU A N     1 
ATOM   928   C CA    . LEU A 1 307 ? 138.021 152.794 179.612 1.00 78.44  ? 278 LEU A CA    1 
ATOM   929   C C     . LEU A 1 307 ? 137.910 153.203 181.080 1.00 78.44  ? 278 LEU A C     1 
ATOM   930   O O     . LEU A 1 307 ? 138.908 153.538 181.718 1.00 78.44  ? 278 LEU A O     1 
ATOM   931   C CB    . LEU A 1 307 ? 139.229 153.478 178.954 1.00 78.44  ? 278 LEU A CB    1 
ATOM   932   C CG    . LEU A 1 307 ? 139.410 153.324 177.438 1.00 78.44  ? 278 LEU A CG    1 
ATOM   933   C CD1   . LEU A 1 307 ? 140.498 154.257 176.932 1.00 78.44  ? 278 LEU A CD1   1 
ATOM   934   C CD2   . LEU A 1 307 ? 139.730 151.885 177.062 1.00 78.44  ? 278 LEU A CD2   1 
ATOM   935   N N     . ARG A 1 308 ? 136.692 153.116 181.623 1.00 74.46  ? 279 ARG A N     1 
ATOM   936   C CA    . ARG A 1 308 ? 136.357 153.732 182.906 1.00 74.46  ? 279 ARG A CA    1 
ATOM   937   C C     . ARG A 1 308 ? 137.111 153.095 184.071 1.00 74.46  ? 279 ARG A C     1 
ATOM   938   O O     . ARG A 1 308 ? 137.591 153.801 184.973 1.00 74.46  ? 279 ARG A O     1 
ATOM   939   C CB    . ARG A 1 308 ? 134.849 153.618 183.121 1.00 74.46  ? 279 ARG A CB    1 
ATOM   940   C CG    . ARG A 1 308 ? 134.254 154.600 184.095 1.00 74.46  ? 279 ARG A CG    1 
ATOM   941   C CD    . ARG A 1 308 ? 132.987 154.032 184.704 1.00 74.46  ? 279 ARG A CD    1 
ATOM   942   N NE    . ARG A 1 308 ? 133.259 153.169 185.849 1.00 74.46  ? 279 ARG A NE    1 
ATOM   943   C CZ    . ARG A 1 308 ? 132.375 152.373 186.441 1.00 74.46  ? 279 ARG A CZ    1 
ATOM   944   N NH1   . ARG A 1 308 ? 131.120 152.277 186.021 1.00 74.46  ? 279 ARG A NH1   1 
ATOM   945   N NH2   . ARG A 1 308 ? 132.759 151.649 187.488 1.00 74.46  ? 279 ARG A NH2   1 
ATOM   946   N N     . GLN A 1 309 ? 137.216 151.763 184.070 1.00 77.44  ? 280 GLN A N     1 
ATOM   947   C CA    . GLN A 1 309 ? 137.785 151.059 185.214 1.00 77.44  ? 280 GLN A CA    1 
ATOM   948   C C     . GLN A 1 309 ? 139.264 151.373 185.400 1.00 77.44  ? 280 GLN A C     1 
ATOM   949   O O     . GLN A 1 309 ? 139.767 151.300 186.526 1.00 77.44  ? 280 GLN A O     1 
ATOM   950   C CB    . GLN A 1 309 ? 137.570 149.555 185.056 1.00 77.44  ? 280 GLN A CB    1 
ATOM   951   C CG    . GLN A 1 309 ? 136.106 149.149 185.082 1.00 77.44  ? 280 GLN A CG    1 
ATOM   952   C CD    . GLN A 1 309 ? 135.909 147.657 185.253 1.00 77.44  ? 280 GLN A CD    1 
ATOM   953   O OE1   . GLN A 1 309 ? 136.805 146.863 184.970 1.00 77.44  ? 280 GLN A OE1   1 
ATOM   954   N NE2   . GLN A 1 309 ? 134.729 147.267 185.722 1.00 77.44  ? 280 GLN A NE2   1 
ATOM   955   N N     . GLU A 1 310 ? 139.965 151.749 184.326 1.00 79.89  ? 281 GLU A N     1 
ATOM   956   C CA    . GLU A 1 310 ? 141.363 152.146 184.455 1.00 79.89  ? 281 GLU A CA    1 
ATOM   957   C C     . GLU A 1 310 ? 141.497 153.403 185.308 1.00 79.89  ? 281 GLU A C     1 
ATOM   958   O O     . GLU A 1 310 ? 142.285 153.433 186.261 1.00 79.89  ? 281 GLU A O     1 
ATOM   959   C CB    . GLU A 1 310 ? 141.974 152.349 183.061 1.00 79.89  ? 281 GLU A CB    1 
ATOM   960   C CG    . GLU A 1 310 ? 143.454 152.788 183.012 1.00 79.89  ? 281 GLU A CG    1 
ATOM   961   C CD    . GLU A 1 310 ? 144.418 151.764 183.593 1.00 79.89  ? 281 GLU A CD    1 
ATOM   962   O OE1   . GLU A 1 310 ? 143.994 150.632 183.905 1.00 79.89  ? 281 GLU A OE1   1 
ATOM   963   O OE2   . GLU A 1 310 ? 145.613 152.098 183.740 1.00 79.89  ? 281 GLU A OE2   1 
ATOM   964   N N     . ILE A 1 311 ? 140.715 154.445 185.000 1.00 75.02  ? 282 ILE A N     1 
ATOM   965   C CA    . ILE A 1 311 ? 140.796 155.666 185.803 1.00 75.02  ? 282 ILE A CA    1 
ATOM   966   C C     . ILE A 1 311 ? 140.267 155.408 187.208 1.00 75.02  ? 282 ILE A C     1 
ATOM   967   O O     . ILE A 1 311 ? 140.773 155.995 188.174 1.00 75.02  ? 282 ILE A O     1 
ATOM   968   C CB    . ILE A 1 311 ? 140.080 156.891 185.178 1.00 75.02  ? 282 ILE A CB    1 
ATOM   969   C CG1   . ILE A 1 311 ? 140.248 157.011 183.653 1.00 75.02  ? 282 ILE A CG1   1 
ATOM   970   C CG2   . ILE A 1 311 ? 140.587 158.201 185.802 1.00 75.02  ? 282 ILE A CG2   1 
ATOM   971   C CD1   . ILE A 1 311 ? 139.212 156.320 182.797 1.00 75.02  ? 282 ILE A CD1   1 
ATOM   972   N N     . ASN A 1 312 ? 139.252 154.546 187.353 1.00 77.09  ? 283 ASN A N     1 
ATOM   973   C CA    . ASN A 1 312 ? 138.728 154.251 188.689 1.00 77.09  ? 283 ASN A CA    1 
ATOM   974   C C     . ASN A 1 312 ? 139.785 153.580 189.565 1.00 77.09  ? 283 ASN A C     1 
ATOM   975   O O     . ASN A 1 312 ? 140.010 153.984 190.715 1.00 77.09  ? 283 ASN A O     1 
ATOM   976   C CB    . ASN A 1 312 ? 137.473 153.365 188.589 1.00 77.09  ? 283 ASN A CB    1 
ATOM   977   C CG    . ASN A 1 312 ? 136.335 153.790 189.532 1.00 77.09  ? 283 ASN A CG    1 
ATOM   978   O OD1   . ASN A 1 312 ? 136.459 154.702 190.353 1.00 77.09  ? 283 ASN A OD1   1 
ATOM   979   N ND2   . ASN A 1 312 ? 135.205 153.105 189.404 1.00 77.09  ? 283 ASN A ND2   1 
ATOM   980   N N     . LYS A 1 313 ? 140.473 152.572 189.024 1.00 83.73  ? 284 LYS A N     1 
ATOM   981   C CA    . LYS A 1 313 ? 141.528 151.911 189.782 1.00 83.73  ? 284 LYS A CA    1 
ATOM   982   C C     . LYS A 1 313 ? 142.708 152.845 190.021 1.00 83.73  ? 284 LYS A C     1 
ATOM   983   O O     . LYS A 1 313 ? 143.352 152.767 191.074 1.00 83.73  ? 284 LYS A O     1 
ATOM   984   C CB    . LYS A 1 313 ? 141.982 150.649 189.045 1.00 83.73  ? 284 LYS A CB    1 
ATOM   985   C CG    . LYS A 1 313 ? 142.850 149.674 189.863 1.00 83.73  ? 284 LYS A CG    1 
ATOM   986   C CD    . LYS A 1 313 ? 142.092 148.938 190.982 1.00 83.73  ? 284 LYS A CD    1 
ATOM   987   C CE    . LYS A 1 313 ? 141.052 147.959 190.446 1.00 83.73  ? 284 LYS A CE    1 
ATOM   988   N NZ    . LYS A 1 313 ? 140.527 147.058 191.508 1.00 83.73  ? 284 LYS A NZ    1 
ATOM   989   N N     . VAL A 1 314 ? 143.000 153.738 189.070 1.00 82.19  ? 285 VAL A N     1 
ATOM   990   C CA    . VAL A 1 314 ? 144.111 154.668 189.241 1.00 82.19  ? 285 VAL A CA    1 
ATOM   991   C C     . VAL A 1 314 ? 143.828 155.640 190.383 1.00 82.19  ? 285 VAL A C     1 
ATOM   992   O O     . VAL A 1 314 ? 144.702 155.895 191.221 1.00 82.19  ? 285 VAL A O     1 
ATOM   993   C CB    . VAL A 1 314 ? 144.400 155.397 187.912 1.00 82.19  ? 285 VAL A CB    1 
ATOM   994   C CG1   . VAL A 1 314 ? 145.318 156.601 188.111 1.00 82.19  ? 285 VAL A CG1   1 
ATOM   995   C CG2   . VAL A 1 314 ? 145.051 154.444 186.912 1.00 82.19  ? 285 VAL A CG2   1 
ATOM   996   N N     . VAL A 1 315 ? 142.614 156.197 190.444 1.00 79.52  ? 286 VAL A N     1 
ATOM   997   C CA    . VAL A 1 315 ? 142.311 157.124 191.535 1.00 79.52  ? 286 VAL A CA    1 
ATOM   998   C C     . VAL A 1 315 ? 142.207 156.376 192.861 1.00 79.52  ? 286 VAL A C     1 
ATOM   999   O O     . VAL A 1 315 ? 142.519 156.941 193.919 1.00 79.52  ? 286 VAL A O     1 
ATOM   1000  C CB    . VAL A 1 315 ? 141.046 157.963 191.238 1.00 79.52  ? 286 VAL A CB    1 
ATOM   1001  C CG1   . VAL A 1 315 ? 141.227 158.770 189.950 1.00 79.52  ? 286 VAL A CG1   1 
ATOM   1002  C CG2   . VAL A 1 315 ? 139.771 157.119 191.164 1.00 79.52  ? 286 VAL A CG2   1 
ATOM   1003  N N     . ASN A 1 316 ? 141.769 155.108 192.835 1.00 81.72  ? 287 ASN A N     1 
ATOM   1004  C CA    . ASN A 1 316 ? 141.810 154.286 194.046 1.00 81.72  ? 287 ASN A CA    1 
ATOM   1005  C C     . ASN A 1 316 ? 143.241 154.134 194.552 1.00 81.72  ? 287 ASN A C     1 
ATOM   1006  O O     . ASN A 1 316 ? 143.512 154.285 195.750 1.00 81.72  ? 287 ASN A O     1 
ATOM   1007  C CB    . ASN A 1 316 ? 141.206 152.901 193.780 1.00 81.72  ? 287 ASN A CB    1 
ATOM   1008  C CG    . ASN A 1 316 ? 139.764 152.774 194.253 1.00 81.72  ? 287 ASN A CG    1 
ATOM   1009  O OD1   . ASN A 1 316 ? 139.407 153.211 195.348 1.00 81.72  ? 287 ASN A OD1   1 
ATOM   1010  N ND2   . ASN A 1 316 ? 138.931 152.145 193.429 1.00 81.72  ? 287 ASN A ND2   1 
ATOM   1011  N N     . ARG A 1 317 ? 144.173 153.849 193.638 1.00 86.60  ? 288 ARG A N     1 
ATOM   1012  C CA    . ARG A 1 317 ? 145.579 153.728 194.010 1.00 86.60  ? 288 ARG A CA    1 
ATOM   1013  C C     . ARG A 1 317 ? 146.125 155.051 194.532 1.00 86.60  ? 288 ARG A C     1 
ATOM   1014  O O     . ARG A 1 317 ? 146.925 155.072 195.475 1.00 86.60  ? 288 ARG A O     1 
ATOM   1015  C CB    . ARG A 1 317 ? 146.396 153.257 192.807 1.00 86.60  ? 288 ARG A CB    1 
ATOM   1016  C CG    . ARG A 1 317 ? 146.092 151.822 192.361 1.00 86.60  ? 288 ARG A CG    1 
ATOM   1017  C CD    . ARG A 1 317 ? 147.159 150.805 192.767 1.00 86.60  ? 288 ARG A CD    1 
ATOM   1018  N NE    . ARG A 1 317 ? 147.037 149.573 191.989 1.00 86.60  ? 288 ARG A NE    1 
ATOM   1019  C CZ    . ARG A 1 317 ? 147.598 149.335 190.807 1.00 86.60  ? 288 ARG A CZ    1 
ATOM   1020  N NH1   . ARG A 1 317 ? 148.328 150.245 190.174 1.00 86.60  ? 288 ARG A NH1   1 
ATOM   1021  N NH2   . ARG A 1 317 ? 147.411 148.151 190.232 1.00 86.60  ? 288 ARG A NH2   1 
ATOM   1022  N N     . TYR A 1 318 ? 145.707 156.163 193.924 1.00 85.54  ? 289 TYR A N     1 
ATOM   1023  C CA    . TYR A 1 318 ? 146.177 157.475 194.360 1.00 85.54  ? 289 TYR A CA    1 
ATOM   1024  C C     . TYR A 1 318 ? 145.711 157.786 195.777 1.00 85.54  ? 289 TYR A C     1 
ATOM   1025  O O     . TYR A 1 318 ? 146.512 158.194 196.626 1.00 85.54  ? 289 TYR A O     1 
ATOM   1026  C CB    . TYR A 1 318 ? 145.685 158.560 193.394 1.00 85.54  ? 289 TYR A CB    1 
ATOM   1027  C CG    . TYR A 1 318 ? 146.369 158.657 192.030 1.00 85.54  ? 289 TYR A CG    1 
ATOM   1028  C CD1   . TYR A 1 318 ? 147.298 157.712 191.589 1.00 85.54  ? 289 TYR A CD1   1 
ATOM   1029  C CD2   . TYR A 1 318 ? 146.070 159.714 191.179 1.00 85.54  ? 289 TYR A CD2   1 
ATOM   1030  C CE1   . TYR A 1 318 ? 147.903 157.828 190.354 1.00 85.54  ? 289 TYR A CE1   1 
ATOM   1031  C CE2   . TYR A 1 318 ? 146.669 159.832 189.941 1.00 85.54  ? 289 TYR A CE2   1 
ATOM   1032  C CZ    . TYR A 1 318 ? 147.583 158.886 189.534 1.00 85.54  ? 289 TYR A CZ    1 
ATOM   1033  O OH    . TYR A 1 318 ? 148.180 159.003 188.300 1.00 85.54  ? 289 TYR A OH    1 
ATOM   1034  N N     . ILE A 1 319 ? 144.416 157.600 196.056 1.00 83.69  ? 290 ILE A N     1 
ATOM   1035  C CA    . ILE A 1 319 ? 143.920 157.928 197.392 1.00 83.69  ? 290 ILE A CA    1 
ATOM   1036  C C     . ILE A 1 319 ? 144.457 156.946 198.427 1.00 83.69  ? 290 ILE A C     1 
ATOM   1037  O O     . ILE A 1 319 ? 144.632 157.311 199.596 1.00 83.69  ? 290 ILE A O     1 
ATOM   1038  C CB    . ILE A 1 319 ? 142.377 158.008 197.434 1.00 83.69  ? 290 ILE A CB    1 
ATOM   1039  C CG1   . ILE A 1 319 ? 141.916 158.537 198.802 1.00 83.69  ? 290 ILE A CG1   1 
ATOM   1040  C CG2   . ILE A 1 319 ? 141.716 156.653 197.146 1.00 83.69  ? 290 ILE A CG2   1 
ATOM   1041  C CD1   . ILE A 1 319 ? 140.533 159.128 198.795 1.00 83.69  ? 290 ILE A CD1   1 
ATOM   1042  N N     . ASP A 1 320 ? 144.720 155.694 198.036 1.00 89.22  ? 291 ASP A N     1 
ATOM   1043  C CA    . ASP A 1 320 ? 145.405 154.782 198.948 1.00 89.22  ? 291 ASP A CA    1 
ATOM   1044  C C     . ASP A 1 320 ? 146.820 155.266 199.239 1.00 89.22  ? 291 ASP A C     1 
ATOM   1045  O O     . ASP A 1 320 ? 147.297 155.168 200.376 1.00 89.22  ? 291 ASP A O     1 
ATOM   1046  C CB    . ASP A 1 320 ? 145.433 153.369 198.362 1.00 89.22  ? 291 ASP A CB    1 
ATOM   1047  C CG    . ASP A 1 320 ? 144.055 152.730 198.298 1.00 89.22  ? 291 ASP A CG    1 
ATOM   1048  O OD1   . ASP A 1 320 ? 143.105 153.268 198.906 1.00 89.22  ? 291 ASP A OD1   1 
ATOM   1049  O OD2   . ASP A 1 320 ? 143.924 151.681 197.635 1.00 89.22  ? 291 ASP A OD2   1 
ATOM   1050  N N     . GLU A 1 321 ? 147.506 155.794 198.224 1.00 92.14  ? 292 GLU A N     1 
ATOM   1051  C CA    . GLU A 1 321 ? 148.838 156.354 198.417 1.00 92.14  ? 292 GLU A CA    1 
ATOM   1052  C C     . GLU A 1 321 ? 148.824 157.702 199.131 1.00 92.14  ? 292 GLU A C     1 
ATOM   1053  O O     . GLU A 1 321 ? 149.883 158.142 199.591 1.00 92.14  ? 292 GLU A O     1 
ATOM   1054  C CB    . GLU A 1 321 ? 149.539 156.501 197.065 1.00 92.14  ? 292 GLU A CB    1 
ATOM   1055  C CG    . GLU A 1 321 ? 149.960 155.179 196.440 1.00 92.14  ? 292 GLU A CG    1 
ATOM   1056  C CD    . GLU A 1 321 ? 150.353 155.320 194.983 1.00 92.14  ? 292 GLU A CD    1 
ATOM   1057  O OE1   . GLU A 1 321 ? 150.902 156.378 194.612 1.00 92.14  ? 292 GLU A OE1   1 
ATOM   1058  O OE2   . GLU A 1 321 ? 150.111 154.372 194.207 1.00 92.14  ? 292 GLU A OE2   1 
ATOM   1059  N N     . GLY A 1 322 ? 147.671 158.368 199.231 1.00 89.34  ? 293 GLY A N     1 
ATOM   1060  C CA    . GLY A 1 322 ? 147.578 159.646 199.906 1.00 89.34  ? 293 GLY A CA    1 
ATOM   1061  C C     . GLY A 1 322 ? 147.918 160.857 199.064 1.00 89.34  ? 293 GLY A C     1 
ATOM   1062  O O     . GLY A 1 322 ? 147.825 161.983 199.569 1.00 89.34  ? 293 GLY A O     1 
ATOM   1063  N N     . VAL A 1 323 ? 148.313 160.673 197.801 1.00 90.06  ? 294 VAL A N     1 
ATOM   1064  C CA    . VAL A 1 323 ? 148.593 161.817 196.940 1.00 90.06  ? 294 VAL A CA    1 
ATOM   1065  C C     . VAL A 1 323 ? 147.332 162.608 196.605 1.00 90.06  ? 294 VAL A C     1 
ATOM   1066  O O     . VAL A 1 323 ? 147.431 163.800 196.291 1.00 90.06  ? 294 VAL A O     1 
ATOM   1067  C CB    . VAL A 1 323 ? 149.304 161.363 195.645 1.00 90.06  ? 294 VAL A CB    1 
ATOM   1068  C CG1   . VAL A 1 323 ? 150.594 160.615 195.974 1.00 90.06  ? 294 VAL A CG1   1 
ATOM   1069  C CG2   . VAL A 1 323 ? 148.384 160.514 194.747 1.00 90.06  ? 294 VAL A CG2   1 
ATOM   1070  N N     . ALA A 1 324 ? 146.152 161.976 196.659 1.00 85.12  ? 295 ALA A N     1 
ATOM   1071  C CA    . ALA A 1 324 ? 144.882 162.596 196.306 1.00 85.12  ? 295 ALA A CA    1 
ATOM   1072  C C     . ALA A 1 324 ? 143.853 162.320 197.392 1.00 85.12  ? 295 ALA A C     1 
ATOM   1073  O O     . ALA A 1 324 ? 143.934 161.318 198.108 1.00 85.12  ? 295 ALA A O     1 
ATOM   1074  C CB    . ALA A 1 324 ? 144.361 162.076 194.960 1.00 85.12  ? 295 ALA A CB    1 
ATOM   1075  N N     . GLU A 1 325 ? 142.888 163.232 197.500 1.00 73.63  ? 296 GLU A N     1 
ATOM   1076  C CA    . GLU A 1 325 ? 141.793 163.165 198.458 1.00 73.63  ? 296 GLU A CA    1 
ATOM   1077  C C     . GLU A 1 325 ? 140.481 163.231 197.692 1.00 73.63  ? 296 GLU A C     1 
ATOM   1078  O O     . GLU A 1 325 ? 140.349 164.010 196.743 1.00 73.63  ? 296 GLU A O     1 
ATOM   1079  C CB    . GLU A 1 325 ? 141.890 164.315 199.474 1.00 73.63  ? 296 GLU A CB    1 
ATOM   1080  C CG    . GLU A 1 325 ? 140.739 164.424 200.473 1.00 73.63  ? 296 GLU A CG    1 
ATOM   1081  C CD    . GLU A 1 325 ? 140.998 165.478 201.531 1.00 73.63  ? 296 GLU A CD    1 
ATOM   1082  O OE1   . GLU A 1 325 ? 142.062 165.421 202.182 1.00 73.63  ? 296 GLU A OE1   1 
ATOM   1083  O OE2   . GLU A 1 325 ? 140.139 166.367 201.707 1.00 73.63  ? 296 GLU A OE2   1 
ATOM   1084  N N     . LEU A 1 326 ? 139.516 162.415 198.117 1.00 64.42  ? 297 LEU A N     1 
ATOM   1085  C CA    . LEU A 1 326 ? 138.229 162.264 197.445 1.00 64.42  ? 297 LEU A CA    1 
ATOM   1086  C C     . LEU A 1 326 ? 137.167 163.045 198.211 1.00 64.42  ? 297 LEU A C     1 
ATOM   1087  O O     . LEU A 1 326 ? 136.985 162.826 199.414 1.00 64.42  ? 297 LEU A O     1 
ATOM   1088  C CB    . LEU A 1 326 ? 137.846 160.785 197.359 1.00 64.42  ? 297 LEU A CB    1 
ATOM   1089  C CG    . LEU A 1 326 ? 136.593 160.369 196.580 1.00 64.42  ? 297 LEU A CG    1 
ATOM   1090  C CD1   . LEU A 1 326 ? 136.686 160.750 195.111 1.00 64.42  ? 297 LEU A CD1   1 
ATOM   1091  C CD2   . LEU A 1 326 ? 136.346 158.872 196.725 1.00 64.42  ? 297 LEU A CD2   1 
ATOM   1092  N N     . VAL A 1 327 ? 136.487 163.950 197.517 1.00 56.80  ? 298 VAL A N     1 
ATOM   1093  C CA    . VAL A 1 327 ? 135.342 164.688 198.034 1.00 56.80  ? 298 VAL A CA    1 
ATOM   1094  C C     . VAL A 1 327 ? 134.142 164.375 197.136 1.00 56.80  ? 298 VAL A C     1 
ATOM   1095  O O     . VAL A 1 327 ? 134.015 164.923 196.039 1.00 56.80  ? 298 VAL A O     1 
ATOM   1096  C CB    . VAL A 1 327 ? 135.614 166.206 198.105 1.00 56.80  ? 298 VAL A CB    1 
ATOM   1097  C CG1   . VAL A 1 327 ? 136.391 166.545 199.374 1.00 56.80  ? 298 VAL A CG1   1 
ATOM   1098  C CG2   . VAL A 1 327 ? 136.379 166.751 196.891 1.00 56.80  ? 298 VAL A CG2   1 
ATOM   1099  N N     . PRO A 1 328 ? 133.263 163.444 197.534 1.00 50.56  ? 299 PRO A N     1 
ATOM   1100  C CA    . PRO A 1 328 ? 132.085 163.175 196.695 1.00 50.56  ? 299 PRO A CA    1 
ATOM   1101  C C     . PRO A 1 328 ? 131.121 164.352 196.693 1.00 50.56  ? 299 PRO A C     1 
ATOM   1102  O O     . PRO A 1 328 ? 130.804 164.917 197.742 1.00 50.56  ? 299 PRO A O     1 
ATOM   1103  C CB    . PRO A 1 328 ? 131.457 161.933 197.340 1.00 50.56  ? 299 PRO A CB    1 
ATOM   1104  C CG    . PRO A 1 328 ? 132.533 161.313 198.111 1.00 50.56  ? 299 PRO A CG    1 
ATOM   1105  C CD    . PRO A 1 328 ? 133.361 162.439 198.613 1.00 50.56  ? 299 PRO A CD    1 
ATOM   1106  N N     . GLY A 1 329 ? 130.651 164.709 195.498 1.00 42.32  ? 300 GLY A N     1 
ATOM   1107  C CA    . GLY A 1 329 ? 129.691 165.777 195.328 1.00 42.32  ? 300 GLY A CA    1 
ATOM   1108  C C     . GLY A 1 329 ? 128.263 165.281 195.412 1.00 42.32  ? 300 GLY A C     1 
ATOM   1109  O O     . GLY A 1 329 ? 127.984 164.153 195.823 1.00 42.32  ? 300 GLY A O     1 
ATOM   1110  N N     . VAL A 1 330 ? 127.348 166.152 194.994 1.00 35.46  ? 301 VAL A N     1 
ATOM   1111  C CA    . VAL A 1 330 ? 125.909 165.927 195.066 1.00 35.46  ? 301 VAL A CA    1 
ATOM   1112  C C     . VAL A 1 330 ? 125.389 165.893 193.637 1.00 35.46  ? 301 VAL A C     1 
ATOM   1113  O O     . VAL A 1 330 ? 125.310 166.936 192.975 1.00 35.46  ? 301 VAL A O     1 
ATOM   1114  C CB    . VAL A 1 330 ? 125.209 167.017 195.889 1.00 35.46  ? 301 VAL A CB    1 
ATOM   1115  C CG1   . VAL A 1 330 ? 123.688 166.969 195.705 1.00 35.46  ? 301 VAL A CG1   1 
ATOM   1116  C CG2   . VAL A 1 330 ? 125.588 166.884 197.360 1.00 35.46  ? 301 VAL A CG2   1 
ATOM   1117  N N     . LEU A 1 331 ? 125.032 164.700 193.163 1.00 39.94  ? 302 LEU A N     1 
ATOM   1118  C CA    . LEU A 1 331 ? 124.363 164.533 191.875 1.00 39.94  ? 302 LEU A CA    1 
ATOM   1119  C C     . LEU A 1 331 ? 122.875 164.692 192.135 1.00 39.94  ? 302 LEU A C     1 
ATOM   1120  O O     . LEU A 1 331 ? 122.226 163.773 192.638 1.00 39.94  ? 302 LEU A O     1 
ATOM   1121  C CB    . LEU A 1 331 ? 124.685 163.172 191.266 1.00 39.94  ? 302 LEU A CB    1 
ATOM   1122  C CG    . LEU A 1 331 ? 123.946 162.726 189.995 1.00 39.94  ? 302 LEU A CG    1 
ATOM   1123  C CD1   . LEU A 1 331 ? 124.355 163.579 188.818 1.00 39.94  ? 302 LEU A CD1   1 
ATOM   1124  C CD2   . LEU A 1 331 ? 124.227 161.264 189.725 1.00 39.94  ? 302 LEU A CD2   1 
ATOM   1125  N N     . PHE A 1 332 ? 122.331 165.852 191.787 1.00 32.18  ? 303 PHE A N     1 
ATOM   1126  C CA    . PHE A 1 332 ? 120.920 166.147 191.983 1.00 32.18  ? 303 PHE A CA    1 
ATOM   1127  C C     . PHE A 1 332 ? 120.176 165.864 190.686 1.00 32.18  ? 303 PHE A C     1 
ATOM   1128  O O     . PHE A 1 332 ? 120.597 166.318 189.617 1.00 32.18  ? 303 PHE A O     1 
ATOM   1129  C CB    . PHE A 1 332 ? 120.733 167.599 192.411 1.00 32.18  ? 303 PHE A CB    1 
ATOM   1130  C CG    . PHE A 1 332 ? 119.312 167.978 192.618 1.00 32.18  ? 303 PHE A CG    1 
ATOM   1131  C CD1   . PHE A 1 332 ? 118.658 167.639 193.783 1.00 32.18  ? 303 PHE A CD1   1 
ATOM   1132  C CD2   . PHE A 1 332 ? 118.620 168.654 191.639 1.00 32.18  ? 303 PHE A CD2   1 
ATOM   1133  C CE1   . PHE A 1 332 ? 117.347 167.984 193.971 1.00 32.18  ? 303 PHE A CE1   1 
ATOM   1134  C CE2   . PHE A 1 332 ? 117.316 168.983 191.816 1.00 32.18  ? 303 PHE A CE2   1 
ATOM   1135  C CZ    . PHE A 1 332 ? 116.675 168.659 192.986 1.00 32.18  ? 303 PHE A CZ    1 
ATOM   1136  N N     . ILE A 1 333 ? 119.074 165.120 190.786 1.00 37.24  ? 304 ILE A N     1 
ATOM   1137  C CA    . ILE A 1 333 ? 118.288 164.669 189.634 1.00 37.24  ? 304 ILE A CA    1 
ATOM   1138  C C     . ILE A 1 333 ? 116.836 165.034 189.918 1.00 37.24  ? 304 ILE A C     1 
ATOM   1139  O O     . ILE A 1 333 ? 116.145 164.325 190.657 1.00 37.24  ? 304 ILE A O     1 
ATOM   1140  C CB    . ILE A 1 333 ? 118.437 163.162 189.370 1.00 37.24  ? 304 ILE A CB    1 
ATOM   1141  C CG1   . ILE A 1 333 ? 119.888 162.802 189.003 1.00 37.24  ? 304 ILE A CG1   1 
ATOM   1142  C CG2   . ILE A 1 333 ? 117.462 162.722 188.263 1.00 37.24  ? 304 ILE A CG2   1 
ATOM   1143  C CD1   . ILE A 1 333 ? 120.217 161.321 189.101 1.00 37.24  ? 304 ILE A CD1   1 
ATOM   1144  N N     . ASP A 1 334 ? 116.367 166.110 189.306 1.00 38.93  ? 305 ASP A N     1 
ATOM   1145  C CA    . ASP A 1 334 ? 114.957 166.516 189.471 1.00 38.93  ? 305 ASP A CA    1 
ATOM   1146  C C     . ASP A 1 334 ? 114.162 165.794 188.393 1.00 38.93  ? 305 ASP A C     1 
ATOM   1147  O O     . ASP A 1 334 ? 114.786 165.352 187.424 1.00 38.93  ? 305 ASP A O     1 
ATOM   1148  C CB    . ASP A 1 334 ? 114.813 168.024 189.412 1.00 38.93  ? 305 ASP A CB    1 
ATOM   1149  C CG    . ASP A 1 334 ? 113.663 168.633 190.203 1.00 38.93  ? 305 ASP A CG    1 
ATOM   1150  O OD1   . ASP A 1 334 ? 112.884 167.871 190.808 1.00 38.93  ? 305 ASP A OD1   1 
ATOM   1151  O OD2   . ASP A 1 334 ? 113.562 169.877 190.219 1.00 38.93  ? 305 ASP A OD2   1 
ATOM   1152  N N     . GLU A 1 335 ? 112.863 165.641 188.574 1.00 44.35  ? 306 GLU A N     1 
ATOM   1153  C CA    . GLU A 1 335 ? 111.943 165.002 187.628 1.00 44.35  ? 306 GLU A CA    1 
ATOM   1154  C C     . GLU A 1 335 ? 112.338 163.544 187.382 1.00 44.35  ? 306 GLU A C     1 
ATOM   1155  O O     . GLU A 1 335 ? 112.489 163.102 186.242 1.00 44.35  ? 306 GLU A O     1 
ATOM   1156  C CB    . GLU A 1 335 ? 111.882 165.776 186.305 1.00 44.35  ? 306 GLU A CB    1 
ATOM   1157  C CG    . GLU A 1 335 ? 111.685 167.292 186.424 1.00 44.35  ? 306 GLU A CG    1 
ATOM   1158  C CD    . GLU A 1 335 ? 110.367 167.676 187.068 1.00 44.35  ? 306 GLU A CD    1 
ATOM   1159  O OE1   . GLU A 1 335 ? 109.394 166.905 186.947 1.00 44.35  ? 306 GLU A OE1   1 
ATOM   1160  O OE2   . GLU A 1 335 ? 110.305 168.754 187.695 1.00 44.35  ? 306 GLU A OE2   1 
ATOM   1161  N N     . VAL A 1 336 ? 112.519 162.800 188.476 1.00 43.40  ? 307 VAL A N     1 
ATOM   1162  C CA    . VAL A 1 336 ? 113.066 161.447 188.390 1.00 43.40  ? 307 VAL A CA    1 
ATOM   1163  C C     . VAL A 1 336 ? 112.121 160.496 187.660 1.00 43.40  ? 307 VAL A C     1 
ATOM   1164  O O     . VAL A 1 336 ? 112.566 159.488 187.100 1.00 43.40  ? 307 VAL A O     1 
ATOM   1165  C CB    . VAL A 1 336 ? 113.406 160.934 189.803 1.00 43.40  ? 307 VAL A CB    1 
ATOM   1166  C CG1   . VAL A 1 336 ? 112.146 160.534 190.567 1.00 43.40  ? 307 VAL A CG1   1 
ATOM   1167  C CG2   . VAL A 1 336 ? 114.387 159.773 189.733 1.00 43.40  ? 307 VAL A CG2   1 
ATOM   1168  N N     . HIS A 1 337 ? 110.815 160.781 187.660 1.00 50.93  ? 308 HIS A N     1 
ATOM   1169  C CA    . HIS A 1 337 ? 109.854 159.916 186.978 1.00 50.93  ? 308 HIS A CA    1 
ATOM   1170  C C     . HIS A 1 337 ? 110.084 159.839 185.472 1.00 50.93  ? 308 HIS A C     1 
ATOM   1171  O O     . HIS A 1 337 ? 109.679 158.852 184.849 1.00 50.93  ? 308 HIS A O     1 
ATOM   1172  C CB    . HIS A 1 337 ? 108.428 160.400 187.243 1.00 50.93  ? 308 HIS A CB    1 
ATOM   1173  C CG    . HIS A 1 337 ? 108.156 161.782 186.737 1.00 50.93  ? 308 HIS A CG    1 
ATOM   1174  N ND1   . HIS A 1 337 ? 108.447 162.911 187.471 1.00 50.93  ? 308 HIS A ND1   1 
ATOM   1175  C CD2   . HIS A 1 337 ? 107.631 162.218 185.568 1.00 50.93  ? 308 HIS A CD2   1 
ATOM   1176  C CE1   . HIS A 1 337 ? 108.110 163.983 186.777 1.00 50.93  ? 308 HIS A CE1   1 
ATOM   1177  N NE2   . HIS A 1 337 ? 107.610 163.590 185.620 1.00 50.93  ? 308 HIS A NE2   1 
ATOM   1178  N N     . MET A 1 338 ? 110.716 160.848 184.870 1.00 55.49  ? 309 MET A N     1 
ATOM   1179  C CA    . MET A 1 338 ? 110.985 160.797 183.437 1.00 55.49  ? 309 MET A CA    1 
ATOM   1180  C C     . MET A 1 338 ? 112.005 159.725 183.072 1.00 55.49  ? 309 MET A C     1 
ATOM   1181  O O     . MET A 1 338 ? 112.002 159.256 181.930 1.00 55.49  ? 309 MET A O     1 
ATOM   1182  C CB    . MET A 1 338 ? 111.472 162.159 182.929 1.00 55.49  ? 309 MET A CB    1 
ATOM   1183  C CG    . MET A 1 338 ? 110.372 163.048 182.357 1.00 55.49  ? 309 MET A CG    1 
ATOM   1184  S SD    . MET A 1 338 ? 111.021 164.470 181.462 1.00 55.49  ? 309 MET A SD    1 
ATOM   1185  C CE    . MET A 1 338 ? 109.595 165.552 181.466 1.00 55.49  ? 309 MET A CE    1 
ATOM   1186  N N     . LEU A 1 339 ? 112.877 159.333 183.999 1.00 52.33  ? 310 LEU A N     1 
ATOM   1187  C CA    . LEU A 1 339 ? 113.831 158.269 183.720 1.00 52.33  ? 310 LEU A CA    1 
ATOM   1188  C C     . LEU A 1 339 ? 113.105 156.945 183.514 1.00 52.33  ? 310 LEU A C     1 
ATOM   1189  O O     . LEU A 1 339 ? 112.030 156.708 184.073 1.00 52.33  ? 310 LEU A O     1 
ATOM   1190  C CB    . LEU A 1 339 ? 114.838 158.129 184.865 1.00 52.33  ? 310 LEU A CB    1 
ATOM   1191  C CG    . LEU A 1 339 ? 115.799 159.279 185.188 1.00 52.33  ? 310 LEU A CG    1 
ATOM   1192  C CD1   . LEU A 1 339 ? 116.791 158.826 186.245 1.00 52.33  ? 310 LEU A CD1   1 
ATOM   1193  C CD2   . LEU A 1 339 ? 116.543 159.787 183.965 1.00 52.33  ? 310 LEU A CD2   1 
ATOM   1194  N N     . ASP A 1 340 ? 113.715 156.077 182.707 1.00 58.64  ? 311 ASP A N     1 
ATOM   1195  C CA    . ASP A 1 340 ? 113.149 154.794 182.297 1.00 58.64  ? 311 ASP A CA    1 
ATOM   1196  C C     . ASP A 1 340 ? 113.881 153.656 183.006 1.00 58.64  ? 311 ASP A C     1 
ATOM   1197  O O     . ASP A 1 340 ? 114.820 153.876 183.777 1.00 58.64  ? 311 ASP A O     1 
ATOM   1198  C CB    . ASP A 1 340 ? 113.187 154.647 180.766 1.00 58.64  ? 311 ASP A CB    1 
ATOM   1199  C CG    . ASP A 1 340 ? 114.576 154.847 180.172 1.00 58.64  ? 311 ASP A CG    1 
ATOM   1200  O OD1   . ASP A 1 340 ? 115.546 155.027 180.937 1.00 58.64  ? 311 ASP A OD1   1 
ATOM   1201  O OD2   . ASP A 1 340 ? 114.692 154.827 178.929 1.00 58.64  ? 311 ASP A OD2   1 
ATOM   1202  N N     . MET A 1 341 ? 113.425 152.426 182.743 1.00 58.90  ? 312 MET A N     1 
ATOM   1203  C CA    . MET A 1 341 ? 113.944 151.263 183.460 1.00 58.90  ? 312 MET A CA    1 
ATOM   1204  C C     . MET A 1 341 ? 115.419 151.021 183.169 1.00 58.90  ? 312 MET A C     1 
ATOM   1205  O O     . MET A 1 341 ? 116.141 150.526 184.040 1.00 58.90  ? 312 MET A O     1 
ATOM   1206  C CB    . MET A 1 341 ? 113.139 150.011 183.108 1.00 58.90  ? 312 MET A CB    1 
ATOM   1207  C CG    . MET A 1 341 ? 111.904 149.789 183.985 1.00 58.90  ? 312 MET A CG    1 
ATOM   1208  S SD    . MET A 1 341 ? 112.150 149.428 185.747 1.00 58.90  ? 312 MET A SD    1 
ATOM   1209  C CE    . MET A 1 341 ? 113.511 148.263 185.762 1.00 58.90  ? 312 MET A CE    1 
ATOM   1210  N N     . GLU A 1 342 ? 115.884 151.352 181.964 1.00 58.49  ? 313 GLU A N     1 
ATOM   1211  C CA    . GLU A 1 342 ? 117.313 151.254 181.683 1.00 58.49  ? 313 GLU A CA    1 
ATOM   1212  C C     . GLU A 1 342 ? 118.100 152.235 182.540 1.00 58.49  ? 313 GLU A C     1 
ATOM   1213  O O     . GLU A 1 342 ? 119.131 151.877 183.125 1.00 58.49  ? 313 GLU A O     1 
ATOM   1214  C CB    . GLU A 1 342 ? 117.582 151.507 180.199 1.00 58.49  ? 313 GLU A CB    1 
ATOM   1215  C CG    . GLU A 1 342 ? 116.759 150.639 179.246 1.00 58.49  ? 313 GLU A CG    1 
ATOM   1216  C CD    . GLU A 1 342 ? 115.596 151.385 178.612 1.00 58.49  ? 313 GLU A CD    1 
ATOM   1217  O OE1   . GLU A 1 342 ? 115.819 152.468 178.031 1.00 58.49  ? 313 GLU A OE1   1 
ATOM   1218  O OE2   . GLU A 1 342 ? 114.455 150.887 178.694 1.00 58.49  ? 313 GLU A OE2   1 
ATOM   1219  N N     . CYS A 1 343 ? 117.612 153.475 182.641 1.00 57.22  ? 314 CYS A N     1 
ATOM   1220  C CA    . CYS A 1 343 ? 118.267 154.481 183.471 1.00 57.22  ? 314 CYS A CA    1 
ATOM   1221  C C     . CYS A 1 343 ? 118.253 154.086 184.941 1.00 57.22  ? 314 CYS A C     1 
ATOM   1222  O O     . CYS A 1 343 ? 119.268 154.215 185.635 1.00 57.22  ? 314 CYS A O     1 
ATOM   1223  C CB    . CYS A 1 343 ? 117.583 155.834 183.281 1.00 57.22  ? 314 CYS A CB    1 
ATOM   1224  S SG    . CYS A 1 343 ? 118.061 156.704 181.776 1.00 57.22  ? 314 CYS A SG    1 
ATOM   1225  N N     . PHE A 1 344 ? 117.111 153.601 185.433 1.00 52.53  ? 315 PHE A N     1 
ATOM   1226  C CA    . PHE A 1 344 ? 117.018 153.226 186.840 1.00 52.53  ? 315 PHE A CA    1 
ATOM   1227  C C     . PHE A 1 344 ? 117.889 152.016 187.146 1.00 52.53  ? 315 PHE A C     1 
ATOM   1228  O O     . PHE A 1 344 ? 118.516 151.951 188.208 1.00 52.53  ? 315 PHE A O     1 
ATOM   1229  C CB    . PHE A 1 344 ? 115.560 152.941 187.218 1.00 52.53  ? 315 PHE A CB    1 
ATOM   1230  C CG    . PHE A 1 344 ? 114.716 154.176 187.441 1.00 52.53  ? 315 PHE A CG    1 
ATOM   1231  C CD1   . PHE A 1 344 ? 115.011 155.079 188.450 1.00 52.53  ? 315 PHE A CD1   1 
ATOM   1232  C CD2   . PHE A 1 344 ? 113.610 154.416 186.647 1.00 52.53  ? 315 PHE A CD2   1 
ATOM   1233  C CE1   . PHE A 1 344 ? 114.234 156.199 188.648 1.00 52.53  ? 315 PHE A CE1   1 
ATOM   1234  C CE2   . PHE A 1 344 ? 112.826 155.535 186.844 1.00 52.53  ? 315 PHE A CE2   1 
ATOM   1235  C CZ    . PHE A 1 344 ? 113.139 156.425 187.847 1.00 52.53  ? 315 PHE A CZ    1 
ATOM   1236  N N     . SER A 1 345 ? 117.943 151.048 186.228 1.00 55.16  ? 316 SER A N     1 
ATOM   1237  C CA    . SER A 1 345 ? 118.802 149.886 186.430 1.00 55.16  ? 316 SER A CA    1 
ATOM   1238  C C     . SER A 1 345 ? 120.273 150.284 186.437 1.00 55.16  ? 316 SER A C     1 
ATOM   1239  O O     . SER A 1 345 ? 121.052 149.794 187.266 1.00 55.16  ? 316 SER A O     1 
ATOM   1240  C CB    . SER A 1 345 ? 118.533 148.845 185.345 1.00 55.16  ? 316 SER A CB    1 
ATOM   1241  O OG    . SER A 1 345 ? 117.166 148.473 185.329 1.00 55.16  ? 316 SER A OG    1 
ATOM   1242  N N     . TYR A 1 346 ? 120.670 151.180 185.527 1.00 54.93  ? 317 TYR A N     1 
ATOM   1243  C CA    . TYR A 1 346 ? 122.053 151.643 185.517 1.00 54.93  ? 317 TYR A CA    1 
ATOM   1244  C C     . TYR A 1 346 ? 122.390 152.411 186.787 1.00 54.93  ? 317 TYR A C     1 
ATOM   1245  O O     . TYR A 1 346 ? 123.491 152.267 187.325 1.00 54.93  ? 317 TYR A O     1 
ATOM   1246  C CB    . TYR A 1 346 ? 122.323 152.514 184.295 1.00 54.93  ? 317 TYR A CB    1 
ATOM   1247  C CG    . TYR A 1 346 ? 123.775 152.907 184.189 1.00 54.93  ? 317 TYR A CG    1 
ATOM   1248  C CD1   . TYR A 1 346 ? 124.725 151.996 183.755 1.00 54.93  ? 317 TYR A CD1   1 
ATOM   1249  C CD2   . TYR A 1 346 ? 124.200 154.179 184.545 1.00 54.93  ? 317 TYR A CD2   1 
ATOM   1250  C CE1   . TYR A 1 346 ? 126.054 152.342 183.663 1.00 54.93  ? 317 TYR A CE1   1 
ATOM   1251  C CE2   . TYR A 1 346 ? 125.531 154.534 184.457 1.00 54.93  ? 317 TYR A CE2   1 
ATOM   1252  C CZ    . TYR A 1 346 ? 126.451 153.609 184.015 1.00 54.93  ? 317 TYR A CZ    1 
ATOM   1253  O OH    . TYR A 1 346 ? 127.777 153.941 183.922 1.00 54.93  ? 317 TYR A OH    1 
ATOM   1254  N N     . LEU A 1 347 ? 121.460 153.235 187.278 1.00 50.69  ? 318 LEU A N     1 
ATOM   1255  C CA    . LEU A 1 347 ? 121.697 153.949 188.529 1.00 50.69  ? 318 LEU A CA    1 
ATOM   1256  C C     . LEU A 1 347 ? 121.809 152.985 189.703 1.00 50.69  ? 318 LEU A C     1 
ATOM   1257  O O     . LEU A 1 347 ? 122.659 153.169 190.582 1.00 50.69  ? 318 LEU A O     1 
ATOM   1258  C CB    . LEU A 1 347 ? 120.578 154.960 188.779 1.00 50.69  ? 318 LEU A CB    1 
ATOM   1259  C CG    . LEU A 1 347 ? 120.631 156.275 187.996 1.00 50.69  ? 318 LEU A CG    1 
ATOM   1260  C CD1   . LEU A 1 347 ? 119.319 157.026 188.150 1.00 50.69  ? 318 LEU A CD1   1 
ATOM   1261  C CD2   . LEU A 1 347 ? 121.801 157.150 188.445 1.00 50.69  ? 318 LEU A CD2   1 
ATOM   1262  N N     . ASN A 1 348 ? 120.962 151.954 189.731 1.00 50.33  ? 319 ASN A N     1 
ATOM   1263  C CA    . ASN A 1 348 ? 121.009 150.981 190.817 1.00 50.33  ? 319 ASN A CA    1 
ATOM   1264  C C     . ASN A 1 348 ? 122.323 150.213 190.812 1.00 50.33  ? 319 ASN A C     1 
ATOM   1265  O O     . ASN A 1 348 ? 122.887 149.928 191.874 1.00 50.33  ? 319 ASN A O     1 
ATOM   1266  C CB    . ASN A 1 348 ? 119.825 150.022 190.709 1.00 50.33  ? 319 ASN A CB    1 
ATOM   1267  C CG    . ASN A 1 348 ? 119.736 149.072 191.884 1.00 50.33  ? 319 ASN A CG    1 
ATOM   1268  O OD1   . ASN A 1 348 ? 120.335 149.306 192.933 1.00 50.33  ? 319 ASN A OD1   1 
ATOM   1269  N ND2   . ASN A 1 348 ? 118.980 147.994 191.717 1.00 50.33  ? 319 ASN A ND2   1 
ATOM   1270  N N     . ARG A 1 349 ? 122.830 149.869 189.625 1.00 55.15  ? 320 ARG A N     1 
ATOM   1271  C CA    . ARG A 1 349 ? 124.116 149.180 189.558 1.00 55.15  ? 320 ARG A CA    1 
ATOM   1272  C C     . ARG A 1 349 ? 125.274 150.122 189.875 1.00 55.15  ? 320 ARG A C     1 
ATOM   1273  O O     . ARG A 1 349 ? 126.259 149.710 190.498 1.00 55.15  ? 320 ARG A O     1 
ATOM   1274  C CB    . ARG A 1 349 ? 124.305 148.542 188.183 1.00 55.15  ? 320 ARG A CB    1 
ATOM   1275  C CG    . ARG A 1 349 ? 123.349 147.390 187.899 1.00 55.15  ? 320 ARG A CG    1 
ATOM   1276  C CD    . ARG A 1 349 ? 123.701 146.611 186.629 1.00 55.15  ? 320 ARG A CD    1 
ATOM   1277  N NE    . ARG A 1 349 ? 123.889 147.459 185.451 1.00 55.15  ? 320 ARG A NE    1 
ATOM   1278  C CZ    . ARG A 1 349 ? 125.040 147.968 185.018 1.00 55.15  ? 320 ARG A CZ    1 
ATOM   1279  N NH1   . ARG A 1 349 ? 126.186 147.774 185.658 1.00 55.15  ? 320 ARG A NH1   1 
ATOM   1280  N NH2   . ARG A 1 349 ? 125.043 148.700 183.908 1.00 55.15  ? 320 ARG A NH2   1 
ATOM   1281  N N     . ALA A 1 350 ? 125.179 151.387 189.458 1.00 54.18  ? 321 ALA A N     1 
ATOM   1282  C CA    . ALA A 1 350 ? 126.269 152.336 189.650 1.00 54.18  ? 321 ALA A CA    1 
ATOM   1283  C C     . ALA A 1 350 ? 126.345 152.879 191.070 1.00 54.18  ? 321 ALA A C     1 
ATOM   1284  O O     . ALA A 1 350 ? 127.401 153.381 191.467 1.00 54.18  ? 321 ALA A O     1 
ATOM   1285  C CB    . ALA A 1 350 ? 126.126 153.499 188.668 1.00 54.18  ? 321 ALA A CB    1 
ATOM   1286  N N     . LEU A 1 351 ? 125.257 152.799 191.842 1.00 49.37  ? 322 LEU A N     1 
ATOM   1287  C CA    . LEU A 1 351 ? 125.325 153.178 193.249 1.00 49.37  ? 322 LEU A CA    1 
ATOM   1288  C C     . LEU A 1 351 ? 126.197 152.233 194.069 1.00 49.37  ? 322 LEU A C     1 
ATOM   1289  O O     . LEU A 1 351 ? 126.657 152.620 195.148 1.00 49.37  ? 322 LEU A O     1 
ATOM   1290  C CB    . LEU A 1 351 ? 123.918 153.230 193.851 1.00 49.37  ? 322 LEU A CB    1 
ATOM   1291  C CG    . LEU A 1 351 ? 123.065 154.471 193.560 1.00 49.37  ? 322 LEU A CG    1 
ATOM   1292  C CD1   . LEU A 1 351 ? 121.620 154.225 193.965 1.00 49.37  ? 322 LEU A CD1   1 
ATOM   1293  C CD2   . LEU A 1 351 ? 123.606 155.704 194.273 1.00 49.37  ? 322 LEU A CD2   1 
ATOM   1294  N N     . GLU A 1 352 ? 126.433 151.006 193.592 1.00 54.57  ? 323 GLU A N     1 
ATOM   1295  C CA    . GLU A 1 352 ? 127.273 150.061 194.318 1.00 54.57  ? 323 GLU A CA    1 
ATOM   1296  C C     . GLU A 1 352 ? 128.742 150.468 194.348 1.00 54.57  ? 323 GLU A C     1 
ATOM   1297  O O     . GLU A 1 352 ? 129.485 149.967 195.198 1.00 54.57  ? 323 GLU A O     1 
ATOM   1298  C CB    . GLU A 1 352 ? 127.150 148.667 193.698 1.00 54.57  ? 323 GLU A CB    1 
ATOM   1299  C CG    . GLU A 1 352 ? 125.741 148.075 193.701 1.00 54.57  ? 323 GLU A CG    1 
ATOM   1300  C CD    . GLU A 1 352 ? 125.213 147.798 195.095 1.00 54.57  ? 323 GLU A CD    1 
ATOM   1301  O OE1   . GLU A 1 352 ? 126.019 147.773 196.048 1.00 54.57  ? 323 GLU A OE1   1 
ATOM   1302  O OE2   . GLU A 1 352 ? 123.988 147.608 195.239 1.00 54.57  ? 323 GLU A OE2   1 
ATOM   1303  N N     . SER A 1 353 ? 129.183 151.341 193.442 1.00 60.57  ? 324 SER A N     1 
ATOM   1304  C CA    . SER A 1 353 ? 130.581 151.749 193.414 1.00 60.57  ? 324 SER A CA    1 
ATOM   1305  C C     . SER A 1 353 ? 130.945 152.530 194.671 1.00 60.57  ? 324 SER A C     1 
ATOM   1306  O O     . SER A 1 353 ? 130.153 153.327 195.181 1.00 60.57  ? 324 SER A O     1 
ATOM   1307  C CB    . SER A 1 353 ? 130.861 152.598 192.177 1.00 60.57  ? 324 SER A CB    1 
ATOM   1308  O OG    . SER A 1 353 ? 132.133 153.215 192.267 1.00 60.57  ? 324 SER A OG    1 
ATOM   1309  N N     . SER A 1 354 ? 132.158 152.290 195.174 1.00 62.21  ? 325 SER A N     1 
ATOM   1310  C CA    . SER A 1 354 ? 132.592 152.934 196.409 1.00 62.21  ? 325 SER A CA    1 
ATOM   1311  C C     . SER A 1 354 ? 132.780 154.435 196.234 1.00 62.21  ? 325 SER A C     1 
ATOM   1312  O O     . SER A 1 354 ? 132.515 155.201 197.168 1.00 62.21  ? 325 SER A O     1 
ATOM   1313  C CB    . SER A 1 354 ? 133.891 152.297 196.901 1.00 62.21  ? 325 SER A CB    1 
ATOM   1314  O OG    . SER A 1 354 ? 134.289 152.848 198.144 1.00 62.21  ? 325 SER A OG    1 
ATOM   1315  N N     . LEU A 1 355 ? 133.224 154.874 195.056 1.00 64.78  ? 326 LEU A N     1 
ATOM   1316  C CA    . LEU A 1 355 ? 133.513 156.277 194.790 1.00 64.78  ? 326 LEU A CA    1 
ATOM   1317  C C     . LEU A 1 355 ? 132.294 157.057 194.303 1.00 64.78  ? 326 LEU A C     1 
ATOM   1318  O O     . LEU A 1 355 ? 132.454 158.161 193.772 1.00 64.78  ? 326 LEU A O     1 
ATOM   1319  C CB    . LEU A 1 355 ? 134.638 156.399 193.759 1.00 64.78  ? 326 LEU A CB    1 
ATOM   1320  C CG    . LEU A 1 355 ? 135.962 155.678 194.052 1.00 64.78  ? 326 LEU A CG    1 
ATOM   1321  C CD1   . LEU A 1 355 ? 135.967 154.211 193.582 1.00 64.78  ? 326 LEU A CD1   1 
ATOM   1322  C CD2   . LEU A 1 355 ? 137.128 156.454 193.438 1.00 64.78  ? 326 LEU A CD2   1 
ATOM   1323  N N     . SER A 1 356 ? 131.087 156.520 194.469 1.00 55.64  ? 327 SER A N     1 
ATOM   1324  C CA    . SER A 1 356 ? 129.916 157.178 193.919 1.00 55.64  ? 327 SER A CA    1 
ATOM   1325  C C     . SER A 1 356 ? 129.600 158.454 194.705 1.00 55.64  ? 327 SER A C     1 
ATOM   1326  O O     . SER A 1 356 ? 129.955 158.565 195.882 1.00 55.64  ? 327 SER A O     1 
ATOM   1327  C CB    . SER A 1 356 ? 128.711 156.243 193.954 1.00 55.64  ? 327 SER A CB    1 
ATOM   1328  O OG    . SER A 1 356 ? 128.510 155.713 195.252 1.00 55.64  ? 327 SER A OG    1 
ATOM   1329  N N     . PRO A 1 357 ? 128.923 159.443 194.074 1.00 47.88  ? 328 PRO A N     1 
ATOM   1330  C CA    . PRO A 1 357 ? 128.490 160.624 194.822 1.00 47.88  ? 328 PRO A CA    1 
ATOM   1331  C C     . PRO A 1 357 ? 127.153 160.354 195.487 1.00 47.88  ? 328 PRO A C     1 
ATOM   1332  O O     . PRO A 1 357 ? 126.645 159.231 195.411 1.00 47.88  ? 328 PRO A O     1 
ATOM   1333  C CB    . PRO A 1 357 ? 128.391 161.690 193.729 1.00 47.88  ? 328 PRO A CB    1 
ATOM   1334  C CG    . PRO A 1 357 ? 127.873 160.920 192.569 1.00 47.88  ? 328 PRO A CG    1 
ATOM   1335  C CD    . PRO A 1 357 ? 128.387 159.499 192.702 1.00 47.88  ? 328 PRO A CD    1 
ATOM   1336  N N     . ILE A 1 358 ? 126.573 161.363 196.124 1.00 39.06  ? 329 ILE A N     1 
ATOM   1337  C CA    . ILE A 1 358 ? 125.253 161.249 196.733 1.00 39.06  ? 329 ILE A CA    1 
ATOM   1338  C C     . ILE A 1 358 ? 124.231 161.601 195.663 1.00 39.06  ? 329 ILE A C     1 
ATOM   1339  O O     . ILE A 1 358 ? 124.212 162.731 195.160 1.00 39.06  ? 329 ILE A O     1 
ATOM   1340  C CB    . ILE A 1 358 ? 125.124 162.161 197.962 1.00 39.06  ? 329 ILE A CB    1 
ATOM   1341  C CG1   . ILE A 1 358 ? 126.245 161.835 198.959 1.00 39.06  ? 329 ILE A CG1   1 
ATOM   1342  C CG2   . ILE A 1 358 ? 123.730 162.018 198.619 1.00 39.06  ? 329 ILE A CG2   1 
ATOM   1343  C CD1   . ILE A 1 358 ? 127.392 162.819 198.960 1.00 39.06  ? 329 ILE A CD1   1 
ATOM   1344  N N     . VAL A 1 359 ? 123.395 160.630 195.309 1.00 38.38  ? 330 VAL A N     1 
ATOM   1345  C CA    . VAL A 1 359 ? 122.350 160.813 194.309 1.00 38.38  ? 330 VAL A CA    1 
ATOM   1346  C C     . VAL A 1 359 ? 121.104 161.300 195.039 1.00 38.38  ? 330 VAL A C     1 
ATOM   1347  O O     . VAL A 1 359 ? 120.466 160.536 195.769 1.00 38.38  ? 330 VAL A O     1 
ATOM   1348  C CB    . VAL A 1 359 ? 122.082 159.516 193.535 1.00 38.38  ? 330 VAL A CB    1 
ATOM   1349  C CG1   . VAL A 1 359 ? 121.020 159.742 192.447 1.00 38.38  ? 330 VAL A CG1   1 
ATOM   1350  C CG2   . VAL A 1 359 ? 123.388 158.988 192.943 1.00 38.38  ? 330 VAL A CG2   1 
ATOM   1351  N N     . ILE A 1 360 ? 120.764 162.570 194.836 1.00 31.59  ? 331 ILE A N     1 
ATOM   1352  C CA    . ILE A 1 360 ? 119.587 163.200 195.427 1.00 31.59  ? 331 ILE A CA    1 
ATOM   1353  C C     . ILE A 1 360 ? 118.553 163.281 194.311 1.00 31.59  ? 331 ILE A C     1 
ATOM   1354  O O     . ILE A 1 360 ? 118.571 164.205 193.496 1.00 31.59  ? 331 ILE A O     1 
ATOM   1355  C CB    . ILE A 1 360 ? 119.910 164.578 196.020 1.00 31.59  ? 331 ILE A CB    1 
ATOM   1356  C CG1   . ILE A 1 360 ? 121.101 164.475 196.986 1.00 31.59  ? 331 ILE A CG1   1 
ATOM   1357  C CG2   . ILE A 1 360 ? 118.691 165.190 196.774 1.00 31.59  ? 331 ILE A CG2   1 
ATOM   1358  C CD1   . ILE A 1 360 ? 121.388 165.729 197.783 1.00 31.59  ? 331 ILE A CD1   1 
ATOM   1359  N N     . PHE A 1 361 ? 117.657 162.304 194.263 1.00 35.37  ? 332 PHE A N     1 
ATOM   1360  C CA    . PHE A 1 361 ? 116.471 162.428 193.436 1.00 35.37  ? 332 PHE A CA    1 
ATOM   1361  C C     . PHE A 1 361 ? 115.529 163.451 194.054 1.00 35.37  ? 332 PHE A C     1 
ATOM   1362  O O     . PHE A 1 361 ? 115.515 163.656 195.270 1.00 35.37  ? 332 PHE A O     1 
ATOM   1363  C CB    . PHE A 1 361 ? 115.757 161.083 193.304 1.00 35.37  ? 332 PHE A CB    1 
ATOM   1364  C CG    . PHE A 1 361 ? 116.621 159.979 192.769 1.00 35.37  ? 332 PHE A CG    1 
ATOM   1365  C CD1   . PHE A 1 361 ? 117.218 160.082 191.527 1.00 35.37  ? 332 PHE A CD1   1 
ATOM   1366  C CD2   . PHE A 1 361 ? 116.827 158.832 193.509 1.00 35.37  ? 332 PHE A CD2   1 
ATOM   1367  C CE1   . PHE A 1 361 ? 118.003 159.064 191.037 1.00 35.37  ? 332 PHE A CE1   1 
ATOM   1368  C CE2   . PHE A 1 361 ? 117.615 157.814 193.025 1.00 35.37  ? 332 PHE A CE2   1 
ATOM   1369  C CZ    . PHE A 1 361 ? 118.204 157.930 191.787 1.00 35.37  ? 332 PHE A CZ    1 
ATOM   1370  N N     . ALA A 1 362 ? 114.748 164.108 193.200 1.00 33.57  ? 333 ALA A N     1 
ATOM   1371  C CA    . ALA A 1 362 ? 113.716 165.039 193.635 1.00 33.57  ? 333 ALA A CA    1 
ATOM   1372  C C     . ALA A 1 362 ? 112.475 164.816 192.794 1.00 33.57  ? 333 ALA A C     1 
ATOM   1373  O O     . ALA A 1 362 ? 112.569 164.687 191.570 1.00 33.57  ? 333 ALA A O     1 
ATOM   1374  C CB    . ALA A 1 362 ? 114.170 166.490 193.518 1.00 33.57  ? 333 ALA A CB    1 
ATOM   1375  N N     . THR A 1 363 ? 111.319 164.776 193.455 1.00 38.40  ? 334 THR A N     1 
ATOM   1376  C CA    . THR A 1 363 ? 110.083 164.388 192.792 1.00 38.40  ? 334 THR A CA    1 
ATOM   1377  C C     . THR A 1 363 ? 108.905 165.125 193.408 1.00 38.40  ? 334 THR A C     1 
ATOM   1378  O O     . THR A 1 363 ? 108.925 165.500 194.586 1.00 38.40  ? 334 THR A O     1 
ATOM   1379  C CB    . THR A 1 363 ? 109.879 162.867 192.867 1.00 38.40  ? 334 THR A CB    1 
ATOM   1380  O OG1   . THR A 1 363 ? 108.870 162.465 191.933 1.00 38.40  ? 334 THR A OG1   1 
ATOM   1381  C CG2   . THR A 1 363 ? 109.492 162.422 194.278 1.00 38.40  ? 334 THR A CG2   1 
ATOM   1382  N N     . ASN A 1 364 ? 107.883 165.337 192.573 1.00 40.13  ? 335 ASN A N     1 
ATOM   1383  C CA    . ASN A 1 364 ? 106.613 165.939 192.959 1.00 40.13  ? 335 ASN A CA    1 
ATOM   1384  C C     . ASN A 1 364 ? 105.437 165.144 192.398 1.00 40.13  ? 335 ASN A C     1 
ATOM   1385  O O     . ASN A 1 364 ? 104.381 165.715 192.113 1.00 40.13  ? 335 ASN A O     1 
ATOM   1386  C CB    . ASN A 1 364 ? 106.545 167.395 192.499 1.00 40.13  ? 335 ASN A CB    1 
ATOM   1387  C CG    . ASN A 1 364 ? 106.539 167.534 190.992 1.00 40.13  ? 335 ASN A CG    1 
ATOM   1388  O OD1   . ASN A 1 364 ? 107.593 167.565 190.358 1.00 40.13  ? 335 ASN A OD1   1 
ATOM   1389  N ND2   . ASN A 1 364 ? 105.351 167.633 190.410 1.00 40.13  ? 335 ASN A ND2   1 
ATOM   1390  N N     . ARG A 1 365 ? 105.610 163.828 192.242 1.00 47.51  ? 336 ARG A N     1 
ATOM   1391  C CA    . ARG A 1 365 ? 104.607 162.920 191.698 1.00 47.51  ? 336 ARG A CA    1 
ATOM   1392  C C     . ARG A 1 365 ? 104.387 161.775 192.673 1.00 47.51  ? 336 ARG A C     1 
ATOM   1393  O O     . ARG A 1 365 ? 105.334 161.289 193.296 1.00 47.51  ? 336 ARG A O     1 
ATOM   1394  C CB    . ARG A 1 365 ? 105.037 162.343 190.346 1.00 47.51  ? 336 ARG A CB    1 
ATOM   1395  C CG    . ARG A 1 365 ? 105.348 163.383 189.279 1.00 47.51  ? 336 ARG A CG    1 
ATOM   1396  C CD    . ARG A 1 365 ? 104.797 162.993 187.908 1.00 47.51  ? 336 ARG A CD    1 
ATOM   1397  N NE    . ARG A 1 365 ? 103.405 163.397 187.738 1.00 47.51  ? 336 ARG A NE    1 
ATOM   1398  C CZ    . ARG A 1 365 ? 102.982 164.638 187.522 1.00 47.51  ? 336 ARG A CZ    1 
ATOM   1399  N NH1   . ARG A 1 365 ? 103.819 165.664 187.433 1.00 47.51  ? 336 ARG A NH1   1 
ATOM   1400  N NH2   . ARG A 1 365 ? 101.678 164.861 187.392 1.00 47.51  ? 336 ARG A NH2   1 
ATOM   1401  N N     . GLY A 1 366 ? 103.140 161.328 192.772 1.00 48.69  ? 337 GLY A N     1 
ATOM   1402  C CA    . GLY A 1 366 ? 102.788 160.242 193.661 1.00 48.69  ? 337 GLY A CA    1 
ATOM   1403  C C     . GLY A 1 366 ? 102.924 158.898 192.981 1.00 48.69  ? 337 GLY A C     1 
ATOM   1404  O O     . GLY A 1 366 ? 104.022 158.517 192.567 1.00 48.69  ? 337 GLY A O     1 
ATOM   1405  N N     . VAL A 1 367 ? 101.818 158.165 192.860 1.00 53.43  ? 338 VAL A N     1 
ATOM   1406  C CA    . VAL A 1 367 ? 101.828 156.943 192.068 1.00 53.43  ? 338 VAL A CA    1 
ATOM   1407  C C     . VAL A 1 367 ? 101.964 157.312 190.598 1.00 53.43  ? 338 VAL A C     1 
ATOM   1408  O O     . VAL A 1 367 ? 101.316 158.248 190.109 1.00 53.43  ? 338 VAL A O     1 
ATOM   1409  C CB    . VAL A 1 367 ? 100.565 156.100 192.330 1.00 53.43  ? 338 VAL A CB    1 
ATOM   1410  C CG1   . VAL A 1 367 ? 100.396 155.842 193.816 1.00 53.43  ? 338 VAL A CG1   1 
ATOM   1411  C CG2   . VAL A 1 367 ? 99.310  156.762 191.757 1.00 53.43  ? 338 VAL A CG2   1 
ATOM   1412  N N     . CYS A 1 368 ? 102.839 156.604 189.892 1.00 55.79  ? 339 CYS A N     1 
ATOM   1413  C CA    . CYS A 1 368 ? 103.066 156.894 188.485 1.00 55.79  ? 339 CYS A CA    1 
ATOM   1414  C C     . CYS A 1 368 ? 103.669 155.665 187.827 1.00 55.79  ? 339 CYS A C     1 
ATOM   1415  O O     . CYS A 1 368 ? 104.314 154.850 188.487 1.00 55.79  ? 339 CYS A O     1 
ATOM   1416  C CB    . CYS A 1 368 ? 103.985 158.107 188.306 1.00 55.79  ? 339 CYS A CB    1 
ATOM   1417  S SG    . CYS A 1 368 ? 104.828 158.176 186.712 1.00 55.79  ? 339 CYS A SG    1 
ATOM   1418  N N     . ASN A 1 369 ? 103.434 155.531 186.527 1.00 63.00  ? 340 ASN A N     1 
ATOM   1419  C CA    . ASN A 1 369 ? 103.970 154.404 185.780 1.00 63.00  ? 340 ASN A CA    1 
ATOM   1420  C C     . ASN A 1 369 ? 105.448 154.631 185.501 1.00 63.00  ? 340 ASN A C     1 
ATOM   1421  O O     . ASN A 1 369 ? 105.844 155.711 185.052 1.00 63.00  ? 340 ASN A O     1 
ATOM   1422  C CB    . ASN A 1 369 ? 103.205 154.216 184.472 1.00 63.00  ? 340 ASN A CB    1 
ATOM   1423  C CG    . ASN A 1 369 ? 101.707 154.132 184.681 1.00 63.00  ? 340 ASN A CG    1 
ATOM   1424  O OD1   . ASN A 1 369 ? 101.239 153.638 185.706 1.00 63.00  ? 340 ASN A OD1   1 
ATOM   1425  N ND2   . ASN A 1 369 ? 100.946 154.618 183.708 1.00 63.00  ? 340 ASN A ND2   1 
ATOM   1426  N N     . VAL A 1 370 ? 106.263 153.614 185.773 1.00 60.12  ? 341 VAL A N     1 
ATOM   1427  C CA    . VAL A 1 370 ? 107.679 153.692 185.438 1.00 60.12  ? 341 VAL A CA    1 
ATOM   1428  C C     . VAL A 1 370 ? 107.802 153.718 183.923 1.00 60.12  ? 341 VAL A C     1 
ATOM   1429  O O     . VAL A 1 370 ? 107.173 152.913 183.223 1.00 60.12  ? 341 VAL A O     1 
ATOM   1430  C CB    . VAL A 1 370 ? 108.463 152.519 186.054 1.00 60.12  ? 341 VAL A CB    1 
ATOM   1431  C CG1   . VAL A 1 370 ? 109.970 152.674 185.786 1.00 60.12  ? 341 VAL A CG1   1 
ATOM   1432  C CG2   . VAL A 1 370 ? 108.202 152.405 187.567 1.00 60.12  ? 341 VAL A CG2   1 
ATOM   1433  N N     . ARG A 1 371 ? 108.588 154.661 183.411 1.00 62.21  ? 342 ARG A N     1 
ATOM   1434  C CA    . ARG A 1 371 ? 108.720 154.827 181.970 1.00 62.21  ? 342 ARG A CA    1 
ATOM   1435  C C     . ARG A 1 371 ? 109.385 153.602 181.357 1.00 62.21  ? 342 ARG A C     1 
ATOM   1436  O O     . ARG A 1 371 ? 110.380 153.092 181.882 1.00 62.21  ? 342 ARG A O     1 
ATOM   1437  C CB    . ARG A 1 371 ? 109.524 156.087 181.657 1.00 62.21  ? 342 ARG A CB    1 
ATOM   1438  C CG    . ARG A 1 371 ? 108.826 157.396 182.038 1.00 62.21  ? 342 ARG A CG    1 
ATOM   1439  C CD    . ARG A 1 371 ? 107.576 157.713 181.199 1.00 62.21  ? 342 ARG A CD    1 
ATOM   1440  N NE    . ARG A 1 371 ? 107.776 157.570 179.760 1.00 62.21  ? 342 ARG A NE    1 
ATOM   1441  C CZ    . ARG A 1 371 ? 108.576 158.320 179.009 1.00 62.21  ? 342 ARG A CZ    1 
ATOM   1442  N NH1   . ARG A 1 371 ? 109.270 159.333 179.512 1.00 62.21  ? 342 ARG A NH1   1 
ATOM   1443  N NH2   . ARG A 1 371 ? 108.688 158.046 177.713 1.00 62.21  ? 342 ARG A NH2   1 
ATOM   1444  N N     . GLY A 1 372 ? 108.827 153.132 180.242 1.00 67.02  ? 343 GLY A N     1 
ATOM   1445  C CA    . GLY A 1 372 ? 109.202 151.864 179.654 1.00 67.02  ? 343 GLY A CA    1 
ATOM   1446  C C     . GLY A 1 372 ? 108.448 150.657 180.178 1.00 67.02  ? 343 GLY A C     1 
ATOM   1447  O O     . GLY A 1 372 ? 108.713 149.541 179.712 1.00 67.02  ? 343 GLY A O     1 
ATOM   1448  N N     . THR A 1 373 ? 107.539 150.837 181.143 1.00 68.13  ? 344 THR A N     1 
ATOM   1449  C CA    . THR A 1 373 ? 106.678 149.775 181.653 1.00 68.13  ? 344 THR A CA    1 
ATOM   1450  C C     . THR A 1 373 ? 105.268 150.332 181.796 1.00 68.13  ? 344 THR A C     1 
ATOM   1451  O O     . THR A 1 373 ? 105.002 151.487 181.448 1.00 68.13  ? 344 THR A O     1 
ATOM   1452  C CB    . THR A 1 373 ? 107.164 149.234 183.003 1.00 68.13  ? 344 THR A CB    1 
ATOM   1453  O OG1   . THR A 1 373 ? 106.863 150.184 184.033 1.00 68.13  ? 344 THR A OG1   1 
ATOM   1454  C CG2   . THR A 1 373 ? 108.657 148.961 182.993 1.00 68.13  ? 344 THR A CG2   1 
ATOM   1455  N N     . ASP A 1 374 ? 104.361 149.493 182.319 1.00 75.14  ? 345 ASP A N     1 
ATOM   1456  C CA    . ASP A 1 374 ? 102.953 149.833 182.505 1.00 75.14  ? 345 ASP A CA    1 
ATOM   1457  C C     . ASP A 1 374 ? 102.515 149.927 183.960 1.00 75.14  ? 345 ASP A C     1 
ATOM   1458  O O     . ASP A 1 374 ? 101.555 150.650 184.246 1.00 75.14  ? 345 ASP A O     1 
ATOM   1459  C CB    . ASP A 1 374 ? 102.055 148.795 181.813 1.00 75.14  ? 345 ASP A CB    1 
ATOM   1460  C CG    . ASP A 1 374 ? 102.333 148.666 180.326 1.00 75.14  ? 345 ASP A CG    1 
ATOM   1461  O OD1   . ASP A 1 374 ? 103.247 149.344 179.816 1.00 75.14  ? 345 ASP A OD1   1 
ATOM   1462  O OD2   . ASP A 1 374 ? 101.624 147.881 179.662 1.00 75.14  ? 345 ASP A OD2   1 
ATOM   1463  N N     . MET A 1 375 ? 103.179 149.222 184.884 1.00 69.68  ? 346 MET A N     1 
ATOM   1464  C CA    . MET A 1 375 ? 102.647 149.138 186.240 1.00 69.68  ? 346 MET A CA    1 
ATOM   1465  C C     . MET A 1 375 ? 102.866 150.463 186.984 1.00 69.68  ? 346 MET A C     1 
ATOM   1466  O O     . MET A 1 375 ? 103.947 151.049 186.881 1.00 69.68  ? 346 MET A O     1 
ATOM   1467  C CB    . MET A 1 375 ? 103.304 147.979 187.007 1.00 69.68  ? 346 MET A CB    1 
ATOM   1468  C CG    . MET A 1 375 ? 104.785 148.148 187.420 1.00 69.68  ? 346 MET A CG    1 
ATOM   1469  S SD    . MET A 1 375 ? 105.936 148.264 186.039 1.00 69.68  ? 346 MET A SD    1 
ATOM   1470  C CE    . MET A 1 375 ? 105.724 146.669 185.252 1.00 69.68  ? 346 MET A CE    1 
ATOM   1471  N N     . PRO A 1 376 ? 101.885 150.972 187.741 1.00 64.49  ? 347 PRO A N     1 
ATOM   1472  C CA    . PRO A 1 376 ? 102.187 152.104 188.625 1.00 64.49  ? 347 PRO A CA    1 
ATOM   1473  C C     . PRO A 1 376 ? 103.094 151.692 189.772 1.00 64.49  ? 347 PRO A C     1 
ATOM   1474  O O     . PRO A 1 376 ? 103.127 150.530 190.184 1.00 64.49  ? 347 PRO A O     1 
ATOM   1475  C CB    . PRO A 1 376 ? 100.811 152.547 189.138 1.00 64.49  ? 347 PRO A CB    1 
ATOM   1476  C CG    . PRO A 1 376 ? 99.833  151.957 188.218 1.00 64.49  ? 347 PRO A CG    1 
ATOM   1477  C CD    . PRO A 1 376 ? 100.436 150.688 187.741 1.00 64.49  ? 347 PRO A CD    1 
ATOM   1478  N N     . SER A 1 377 ? 103.838 152.668 190.283 1.00 55.21  ? 348 SER A N     1 
ATOM   1479  C CA    . SER A 1 377 ? 104.724 152.482 191.421 1.00 55.21  ? 348 SER A CA    1 
ATOM   1480  C C     . SER A 1 377 ? 104.860 153.820 192.133 1.00 55.21  ? 348 SER A C     1 
ATOM   1481  O O     . SER A 1 377 ? 104.506 154.862 191.567 1.00 55.21  ? 348 SER A O     1 
ATOM   1482  C CB    . SER A 1 377 ? 106.098 151.960 190.982 1.00 55.21  ? 348 SER A CB    1 
ATOM   1483  O OG    . SER A 1 377 ? 106.904 153.013 190.487 1.00 55.21  ? 348 SER A OG    1 
ATOM   1484  N N     . PRO A 1 378 ? 105.355 153.830 193.378 1.00 47.58  ? 349 PRO A N     1 
ATOM   1485  C CA    . PRO A 1 378 ? 105.483 155.110 194.094 1.00 47.58  ? 349 PRO A CA    1 
ATOM   1486  C C     . PRO A 1 378 ? 106.540 156.003 193.460 1.00 47.58  ? 349 PRO A C     1 
ATOM   1487  O O     . PRO A 1 378 ? 107.660 155.567 193.187 1.00 47.58  ? 349 PRO A O     1 
ATOM   1488  C CB    . PRO A 1 378 ? 105.886 154.693 195.514 1.00 47.58  ? 349 PRO A CB    1 
ATOM   1489  C CG    . PRO A 1 378 ? 105.620 153.249 195.603 1.00 47.58  ? 349 PRO A CG    1 
ATOM   1490  C CD    . PRO A 1 378 ? 105.794 152.710 194.231 1.00 47.58  ? 349 PRO A CD    1 
ATOM   1491  N N     . HIS A 1 379 ? 106.165 157.260 193.216 1.00 44.32  ? 350 HIS A N     1 
ATOM   1492  C CA    . HIS A 1 379 ? 107.063 158.306 192.721 1.00 44.32  ? 350 HIS A CA    1 
ATOM   1493  C C     . HIS A 1 379 ? 107.626 158.013 191.331 1.00 44.32  ? 350 HIS A C     1 
ATOM   1494  O O     . HIS A 1 379 ? 108.603 158.644 190.918 1.00 44.32  ? 350 HIS A O     1 
ATOM   1495  C CB    . HIS A 1 379 ? 108.221 158.544 193.697 1.00 44.32  ? 350 HIS A CB    1 
ATOM   1496  C CG    . HIS A 1 379 ? 107.795 158.689 195.123 1.00 44.32  ? 350 HIS A CG    1 
ATOM   1497  N ND1   . HIS A 1 379 ? 106.851 159.606 195.531 1.00 44.32  ? 350 HIS A ND1   1 
ATOM   1498  C CD2   . HIS A 1 379 ? 108.189 158.033 196.239 1.00 44.32  ? 350 HIS A CD2   1 
ATOM   1499  C CE1   . HIS A 1 379 ? 106.680 159.505 196.837 1.00 44.32  ? 350 HIS A CE1   1 
ATOM   1500  N NE2   . HIS A 1 379 ? 107.481 158.560 197.291 1.00 44.32  ? 350 HIS A NE2   1 
ATOM   1501  N N     . GLY A 1 380 ? 107.032 157.087 190.581 1.00 50.01  ? 351 GLY A N     1 
ATOM   1502  C CA    . GLY A 1 380 ? 107.584 156.709 189.292 1.00 50.01  ? 351 GLY A CA    1 
ATOM   1503  C C     . GLY A 1 380 ? 108.958 156.081 189.364 1.00 50.01  ? 351 GLY A C     1 
ATOM   1504  O O     . GLY A 1 380 ? 109.726 156.189 188.401 1.00 50.01  ? 351 GLY A O     1 
ATOM   1505  N N     . VAL A 1 381 ? 109.284 155.423 190.478 1.00 47.59  ? 352 VAL A N     1 
ATOM   1506  C CA    . VAL A 1 381 ? 110.579 154.782 190.720 1.00 47.59  ? 352 VAL A CA    1 
ATOM   1507  C C     . VAL A 1 381 ? 110.311 153.278 190.791 1.00 47.59  ? 352 VAL A C     1 
ATOM   1508  O O     . VAL A 1 381 ? 109.245 152.888 191.288 1.00 47.59  ? 352 VAL A O     1 
ATOM   1509  C CB    . VAL A 1 381 ? 111.234 155.312 192.011 1.00 47.59  ? 352 VAL A CB    1 
ATOM   1510  C CG1   . VAL A 1 381 ? 112.628 154.713 192.224 1.00 47.59  ? 352 VAL A CG1   1 
ATOM   1511  C CG2   . VAL A 1 381 ? 111.333 156.839 191.989 1.00 47.59  ? 352 VAL A CG2   1 
ATOM   1512  N N     . PRO A 1 382 ? 111.202 152.394 190.330 1.00 49.38  ? 353 PRO A N     1 
ATOM   1513  C CA    . PRO A 1 382 ? 110.987 150.964 190.583 1.00 49.38  ? 353 PRO A CA    1 
ATOM   1514  C C     . PRO A 1 382 ? 111.176 150.623 192.052 1.00 49.38  ? 353 PRO A C     1 
ATOM   1515  O O     . PRO A 1 382 ? 111.815 151.352 192.813 1.00 49.38  ? 353 PRO A O     1 
ATOM   1516  C CB    . PRO A 1 382 ? 112.046 150.277 189.713 1.00 49.38  ? 353 PRO A CB    1 
ATOM   1517  C CG    . PRO A 1 382 ? 113.074 151.298 189.483 1.00 49.38  ? 353 PRO A CG    1 
ATOM   1518  C CD    . PRO A 1 382 ? 112.344 152.593 189.417 1.00 49.38  ? 353 PRO A CD    1 
ATOM   1519  N N     . ILE A 1 383 ? 110.598 149.486 192.447 1.00 47.78  ? 354 ILE A N     1 
ATOM   1520  C CA    . ILE A 1 383 ? 110.704 149.039 193.836 1.00 47.78  ? 354 ILE A CA    1 
ATOM   1521  C C     . ILE A 1 383 ? 112.151 148.696 194.183 1.00 47.78  ? 354 ILE A C     1 
ATOM   1522  O O     . ILE A 1 383 ? 112.584 148.887 195.332 1.00 47.78  ? 354 ILE A O     1 
ATOM   1523  C CB    . ILE A 1 383 ? 109.757 147.849 194.092 1.00 47.78  ? 354 ILE A CB    1 
ATOM   1524  C CG1   . ILE A 1 383 ? 108.291 148.303 194.060 1.00 47.78  ? 354 ILE A CG1   1 
ATOM   1525  C CG2   . ILE A 1 383 ? 110.041 147.201 195.457 1.00 47.78  ? 354 ILE A CG2   1 
ATOM   1526  C CD1   . ILE A 1 383 ? 107.303 147.195 193.733 1.00 47.78  ? 354 ILE A CD1   1 
ATOM   1527  N N     . ASP A 1 384 ? 112.912 148.182 193.210 1.00 49.68  ? 355 ASP A N     1 
ATOM   1528  C CA    . ASP A 1 384 ? 114.286 147.760 193.463 1.00 49.68  ? 355 ASP A CA    1 
ATOM   1529  C C     . ASP A 1 384 ? 115.165 148.931 193.884 1.00 49.68  ? 355 ASP A C     1 
ATOM   1530  O O     . ASP A 1 384 ? 116.016 148.787 194.769 1.00 49.68  ? 355 ASP A O     1 
ATOM   1531  C CB    . ASP A 1 384 ? 114.856 147.085 192.216 1.00 49.68  ? 355 ASP A CB    1 
ATOM   1532  C CG    . ASP A 1 384 ? 114.102 145.825 191.841 1.00 49.68  ? 355 ASP A CG    1 
ATOM   1533  O OD1   . ASP A 1 384 ? 113.008 145.599 192.398 1.00 49.68  ? 355 ASP A OD1   1 
ATOM   1534  O OD2   . ASP A 1 384 ? 114.603 145.060 190.988 1.00 49.68  ? 355 ASP A OD2   1 
ATOM   1535  N N     . LEU A 1 385 ? 114.970 150.100 193.263 1.00 46.69  ? 356 LEU A N     1 
ATOM   1536  C CA    . LEU A 1 385 ? 115.677 151.303 193.693 1.00 46.69  ? 356 LEU A CA    1 
ATOM   1537  C C     . LEU A 1 385 ? 115.040 151.923 194.931 1.00 46.69  ? 356 LEU A C     1 
ATOM   1538  O O     . LEU A 1 385 ? 115.744 152.543 195.732 1.00 46.69  ? 356 LEU A O     1 
ATOM   1539  C CB    . LEU A 1 385 ? 115.725 152.325 192.554 1.00 46.69  ? 356 LEU A CB    1 
ATOM   1540  C CG    . LEU A 1 385 ? 116.497 153.635 192.780 1.00 46.69  ? 356 LEU A CG    1 
ATOM   1541  C CD1   . LEU A 1 385 ? 117.949 153.408 193.182 1.00 46.69  ? 356 LEU A CD1   1 
ATOM   1542  C CD2   . LEU A 1 385 ? 116.440 154.480 191.529 1.00 46.69  ? 356 LEU A CD2   1 
ATOM   1543  N N     . LEU A 1 386 ? 113.725 151.758 195.118 1.00 45.32  ? 357 LEU A N     1 
ATOM   1544  C CA    . LEU A 1 386 ? 113.076 152.259 196.328 1.00 45.32  ? 357 LEU A CA    1 
ATOM   1545  C C     . LEU A 1 386 ? 113.502 151.507 197.582 1.00 45.32  ? 357 LEU A C     1 
ATOM   1546  O O     . LEU A 1 386 ? 113.280 152.009 198.689 1.00 45.32  ? 357 LEU A O     1 
ATOM   1547  C CB    . LEU A 1 386 ? 111.555 152.183 196.201 1.00 45.32  ? 357 LEU A CB    1 
ATOM   1548  C CG    . LEU A 1 386 ? 110.857 153.180 195.276 1.00 45.32  ? 357 LEU A CG    1 
ATOM   1549  C CD1   . LEU A 1 386 ? 109.467 152.684 194.924 1.00 45.32  ? 357 LEU A CD1   1 
ATOM   1550  C CD2   . LEU A 1 386 ? 110.771 154.550 195.925 1.00 45.32  ? 357 LEU A CD2   1 
ATOM   1551  N N     . ASP A 1 387 ? 114.104 150.323 197.447 1.00 50.54  ? 358 ASP A N     1 
ATOM   1552  C CA    . ASP A 1 387 ? 114.647 149.590 198.587 1.00 50.54  ? 358 ASP A CA    1 
ATOM   1553  C C     . ASP A 1 387 ? 115.988 150.154 199.098 1.00 50.54  ? 358 ASP A C     1 
ATOM   1554  O O     . ASP A 1 387 ? 116.628 149.496 199.925 1.00 50.54  ? 358 ASP A O     1 
ATOM   1555  C CB    . ASP A 1 387 ? 114.809 148.106 198.210 1.00 50.54  ? 358 ASP A CB    1 
ATOM   1556  C CG    . ASP A 1 387 ? 113.484 147.345 198.174 1.00 50.54  ? 358 ASP A CG    1 
ATOM   1557  O OD1   . ASP A 1 387 ? 112.443 147.875 198.619 1.00 50.54  ? 358 ASP A OD1   1 
ATOM   1558  O OD2   . ASP A 1 387 ? 113.491 146.192 197.695 1.00 50.54  ? 358 ASP A OD2   1 
ATOM   1559  N N     . ARG A 1 388 ? 116.447 151.329 198.623 1.00 45.42  ? 359 ARG A N     1 
ATOM   1560  C CA    . ARG A 1 388 ? 117.638 151.966 199.178 1.00 45.42  ? 359 ARG A CA    1 
ATOM   1561  C C     . ARG A 1 388 ? 117.542 153.490 199.252 1.00 45.42  ? 359 ARG A C     1 
ATOM   1562  O O     . ARG A 1 388 ? 118.582 154.152 199.361 1.00 45.42  ? 359 ARG A O     1 
ATOM   1563  C CB    . ARG A 1 388 ? 118.872 151.572 198.362 1.00 45.42  ? 359 ARG A CB    1 
ATOM   1564  C CG    . ARG A 1 388 ? 118.997 152.278 197.023 1.00 45.42  ? 359 ARG A CG    1 
ATOM   1565  C CD    . ARG A 1 388 ? 119.803 151.446 196.051 1.00 45.42  ? 359 ARG A CD    1 
ATOM   1566  N NE    . ARG A 1 388 ? 121.044 150.974 196.658 1.00 45.42  ? 359 ARG A NE    1 
ATOM   1567  C CZ    . ARG A 1 388 ? 121.787 149.963 196.223 1.00 45.42  ? 359 ARG A CZ    1 
ATOM   1568  N NH1   . ARG A 1 388 ? 121.466 149.267 195.141 1.00 45.42  ? 359 ARG A NH1   1 
ATOM   1569  N NH2   . ARG A 1 388 ? 122.887 149.637 196.894 1.00 45.42  ? 359 ARG A NH2   1 
ATOM   1570  N N     . LEU A 1 389 ? 116.336 154.063 199.228 1.00 37.91  ? 360 LEU A N     1 
ATOM   1571  C CA    . LEU A 1 389 ? 116.141 155.510 199.246 1.00 37.91  ? 360 LEU A CA    1 
ATOM   1572  C C     . LEU A 1 389 ? 115.824 155.988 200.656 1.00 37.91  ? 360 LEU A C     1 
ATOM   1573  O O     . LEU A 1 389 ? 114.961 155.418 201.331 1.00 37.91  ? 360 LEU A O     1 
ATOM   1574  C CB    . LEU A 1 389 ? 115.006 155.931 198.309 1.00 37.91  ? 360 LEU A CB    1 
ATOM   1575  C CG    . LEU A 1 389 ? 115.127 155.760 196.790 1.00 37.91  ? 360 LEU A CG    1 
ATOM   1576  C CD1   . LEU A 1 389 ? 113.997 156.509 196.118 1.00 37.91  ? 360 LEU A CD1   1 
ATOM   1577  C CD2   . LEU A 1 389 ? 116.459 156.230 196.226 1.00 37.91  ? 360 LEU A CD2   1 
ATOM   1578  N N     . VAL A 1 390 ? 116.530 157.028 201.090 1.00 36.53  ? 361 VAL A N     1 
ATOM   1579  C CA    . VAL A 1 390 ? 116.151 157.814 202.260 1.00 36.53  ? 361 VAL A CA    1 
ATOM   1580  C C     . VAL A 1 390 ? 115.274 158.954 201.760 1.00 36.53  ? 361 VAL A C     1 
ATOM   1581  O O     . VAL A 1 390 ? 115.710 159.755 200.927 1.00 36.53  ? 361 VAL A O     1 
ATOM   1582  C CB    . VAL A 1 390 ? 117.388 158.349 203.000 1.00 36.53  ? 361 VAL A CB    1 
ATOM   1583  C CG1   . VAL A 1 390 ? 116.985 159.343 204.080 1.00 36.53  ? 361 VAL A CG1   1 
ATOM   1584  C CG2   . VAL A 1 390 ? 118.196 157.213 203.616 1.00 36.53  ? 361 VAL A CG2   1 
ATOM   1585  N N     . ILE A 1 391 ? 114.044 159.031 202.266 1.00 34.59  ? 362 ILE A N     1 
ATOM   1586  C CA    . ILE A 1 391 ? 113.021 159.947 201.766 1.00 34.59  ? 362 ILE A CA    1 
ATOM   1587  C C     . ILE A 1 391 ? 112.853 161.070 202.779 1.00 34.59  ? 362 ILE A C     1 
ATOM   1588  O O     . ILE A 1 391 ? 112.728 160.810 203.980 1.00 34.59  ? 362 ILE A O     1 
ATOM   1589  C CB    . ILE A 1 391 ? 111.679 159.231 201.515 1.00 34.59  ? 362 ILE A CB    1 
ATOM   1590  C CG1   . ILE A 1 391 ? 111.862 158.060 200.521 1.00 34.59  ? 362 ILE A CG1   1 
ATOM   1591  C CG2   . ILE A 1 391 ? 110.615 160.276 201.072 1.00 34.59  ? 362 ILE A CG2   1 
ATOM   1592  C CD1   . ILE A 1 391 ? 110.619 157.219 200.248 1.00 34.59  ? 362 ILE A CD1   1 
ATOM   1593  N N     . ILE A 1 392 ? 112.857 162.312 202.292 1.00 31.26  ? 363 ILE A N     1 
ATOM   1594  C CA    . ILE A 1 392 ? 112.619 163.506 203.100 1.00 31.26  ? 363 ILE A CA    1 
ATOM   1595  C C     . ILE A 1 392 ? 111.471 164.275 202.465 1.00 31.26  ? 363 ILE A C     1 
ATOM   1596  O O     . ILE A 1 392 ? 111.449 164.472 201.245 1.00 31.26  ? 363 ILE A O     1 
ATOM   1597  C CB    . ILE A 1 392 ? 113.875 164.393 203.218 1.00 31.26  ? 363 ILE A CB    1 
ATOM   1598  C CG1   . ILE A 1 392 ? 114.969 163.661 204.007 1.00 31.26  ? 363 ILE A CG1   1 
ATOM   1599  C CG2   . ILE A 1 392 ? 113.511 165.755 203.869 1.00 31.26  ? 363 ILE A CG2   1 
ATOM   1600  C CD1   . ILE A 1 392 ? 116.339 164.313 203.965 1.00 31.26  ? 363 ILE A CD1   1 
ATOM   1601  N N     . ARG A 1 393 ? 110.534 164.717 203.297 1.00 36.19  ? 364 ARG A N     1 
ATOM   1602  C CA    . ARG A 1 393 ? 109.361 165.466 202.868 1.00 36.19  ? 364 ARG A CA    1 
ATOM   1603  C C     . ARG A 1 393 ? 109.624 166.955 203.041 1.00 36.19  ? 364 ARG A C     1 
ATOM   1604  O O     . ARG A 1 393 ? 110.092 167.383 204.101 1.00 36.19  ? 364 ARG A O     1 
ATOM   1605  C CB    . ARG A 1 393 ? 108.138 165.044 203.683 1.00 36.19  ? 364 ARG A CB    1 
ATOM   1606  C CG    . ARG A 1 393 ? 106.937 165.977 203.576 1.00 36.19  ? 364 ARG A CG    1 
ATOM   1607  C CD    . ARG A 1 393 ? 105.645 165.281 203.966 1.00 36.19  ? 364 ARG A CD    1 
ATOM   1608  N NE    . ARG A 1 393 ? 105.603 164.989 205.396 1.00 36.19  ? 364 ARG A NE    1 
ATOM   1609  C CZ    . ARG A 1 393 ? 104.510 164.704 206.096 1.00 36.19  ? 364 ARG A CZ    1 
ATOM   1610  N NH1   . ARG A 1 393 ? 103.311 164.631 205.534 1.00 36.19  ? 364 ARG A NH1   1 
ATOM   1611  N NH2   . ARG A 1 393 ? 104.623 164.475 207.401 1.00 36.19  ? 364 ARG A NH2   1 
ATOM   1612  N N     . THR A 1 394 ? 109.324 167.732 202.000 1.00 32.15  ? 365 THR A N     1 
ATOM   1613  C CA    . THR A 1 394 ? 109.431 169.187 202.017 1.00 32.15  ? 365 THR A CA    1 
ATOM   1614  C C     . THR A 1 394 ? 108.028 169.774 201.956 1.00 32.15  ? 365 THR A C     1 
ATOM   1615  O O     . THR A 1 394 ? 107.264 169.466 201.036 1.00 32.15  ? 365 THR A O     1 
ATOM   1616  C CB    . THR A 1 394 ? 110.274 169.690 200.847 1.00 32.15  ? 365 THR A CB    1 
ATOM   1617  O OG1   . THR A 1 394 ? 109.609 169.403 199.614 1.00 32.15  ? 365 THR A OG1   1 
ATOM   1618  C CG2   . THR A 1 394 ? 111.641 169.032 200.845 1.00 32.15  ? 365 THR A CG2   1 
ATOM   1619  N N     . GLN A 1 395 ? 107.698 170.619 202.929 1.00 40.29  ? 366 GLN A N     1 
ATOM   1620  C CA    . GLN A 1 395 ? 106.362 171.181 203.067 1.00 40.29  ? 366 GLN A CA    1 
ATOM   1621  C C     . GLN A 1 395 ? 106.242 172.471 202.268 1.00 40.29  ? 366 GLN A C     1 
ATOM   1622  O O     . GLN A 1 395 ? 107.228 173.179 202.049 1.00 40.29  ? 366 GLN A O     1 
ATOM   1623  C CB    . GLN A 1 395 ? 106.034 171.467 204.537 1.00 40.29  ? 366 GLN A CB    1 
ATOM   1624  C CG    . GLN A 1 395 ? 106.266 170.314 205.516 1.00 40.29  ? 366 GLN A CG    1 
ATOM   1625  C CD    . GLN A 1 395 ? 105.304 169.166 205.311 1.00 40.29  ? 366 GLN A CD    1 
ATOM   1626  O OE1   . GLN A 1 395 ? 104.399 169.239 204.482 1.00 40.29  ? 366 GLN A OE1   1 
ATOM   1627  N NE2   . GLN A 1 395 ? 105.497 168.092 206.066 1.00 40.29  ? 366 GLN A NE2   1 
ATOM   1628  N N     . ILE A 1 396 ? 105.014 172.775 201.840 1.00 40.06  ? 367 ILE A N     1 
ATOM   1629  C CA    . ILE A 1 396 ? 104.739 174.047 201.182 1.00 40.06  ? 367 ILE A CA    1 
ATOM   1630  C C     . ILE A 1 396 ? 104.680 175.159 202.225 1.00 40.06  ? 367 ILE A C     1 
ATOM   1631  O O     . ILE A 1 396 ? 104.476 174.920 203.418 1.00 40.06  ? 367 ILE A O     1 
ATOM   1632  C CB    . ILE A 1 396 ? 103.436 173.966 200.355 1.00 40.06  ? 367 ILE A CB    1 
ATOM   1633  C CG1   . ILE A 1 396 ? 103.374 175.049 199.261 1.00 40.06  ? 367 ILE A CG1   1 
ATOM   1634  C CG2   . ILE A 1 396 ? 102.199 174.004 201.260 1.00 40.06  ? 367 ILE A CG2   1 
ATOM   1635  C CD1   . ILE A 1 396 ? 102.545 174.639 198.065 1.00 40.06  ? 367 ILE A CD1   1 
ATOM   1636  N N     . TYR A 1 397 ? 104.850 176.394 201.761 1.00 35.63  ? 368 TYR A N     1 
ATOM   1637  C CA    . TYR A 1 397 ? 105.113 177.536 202.625 1.00 35.63  ? 368 TYR A CA    1 
ATOM   1638  C C     . TYR A 1 397 ? 103.840 178.306 202.959 1.00 35.63  ? 368 TYR A C     1 
ATOM   1639  O O     . TYR A 1 397 ? 102.838 178.256 202.242 1.00 35.63  ? 368 TYR A O     1 
ATOM   1640  C CB    . TYR A 1 397 ? 106.115 178.487 201.960 1.00 35.63  ? 368 TYR A CB    1 
ATOM   1641  C CG    . TYR A 1 397 ? 107.496 177.907 201.740 1.00 35.63  ? 368 TYR A CG    1 
ATOM   1642  C CD1   . TYR A 1 397 ? 108.220 177.359 202.788 1.00 35.63  ? 368 TYR A CD1   1 
ATOM   1643  C CD2   . TYR A 1 397 ? 108.078 177.919 200.483 1.00 35.63  ? 368 TYR A CD2   1 
ATOM   1644  C CE1   . TYR A 1 397 ? 109.468 176.835 202.592 1.00 35.63  ? 368 TYR A CE1   1 
ATOM   1645  C CE2   . TYR A 1 397 ? 109.333 177.397 200.278 1.00 35.63  ? 368 TYR A CE2   1 
ATOM   1646  C CZ    . TYR A 1 397 ? 110.021 176.855 201.339 1.00 35.63  ? 368 TYR A CZ    1 
ATOM   1647  O OH    . TYR A 1 397 ? 111.274 176.329 201.154 1.00 35.63  ? 368 TYR A OH    1 
ATOM   1648  N N     . ASP A 1 398 ? 103.905 179.023 204.075 1.00 47.69  ? 369 ASP A N     1 
ATOM   1649  C CA    . ASP A 1 398 ? 102.873 179.965 204.474 1.00 47.69  ? 369 ASP A CA    1 
ATOM   1650  C C     . ASP A 1 398 ? 103.025 181.248 203.663 1.00 47.69  ? 369 ASP A C     1 
ATOM   1651  O O     . ASP A 1 398 ? 103.996 181.408 202.922 1.00 47.69  ? 369 ASP A O     1 
ATOM   1652  C CB    . ASP A 1 398 ? 102.990 180.245 205.971 1.00 47.69  ? 369 ASP A CB    1 
ATOM   1653  C CG    . ASP A 1 398 ? 102.732 179.015 206.821 1.00 47.69  ? 369 ASP A CG    1 
ATOM   1654  O OD1   . ASP A 1 398 ? 102.131 178.045 206.313 1.00 47.69  ? 369 ASP A OD1   1 
ATOM   1655  O OD2   . ASP A 1 398 ? 103.132 179.019 208.004 1.00 47.69  ? 369 ASP A OD2   1 
ATOM   1656  N N     . PRO A 1 399 ? 102.061 182.176 203.747 1.00 44.04  ? 370 PRO A N     1 
ATOM   1657  C CA    . PRO A 1 399 ? 102.281 183.488 203.112 1.00 44.04  ? 370 PRO A CA    1 
ATOM   1658  C C     . PRO A 1 399 ? 103.470 184.248 203.677 1.00 44.04  ? 370 PRO A C     1 
ATOM   1659  O O     . PRO A 1 399 ? 104.184 184.918 202.922 1.00 44.04  ? 370 PRO A O     1 
ATOM   1660  C CB    . PRO A 1 399 ? 100.962 184.228 203.368 1.00 44.04  ? 370 PRO A CB    1 
ATOM   1661  C CG    . PRO A 1 399 ? 99.961  183.166 203.574 1.00 44.04  ? 370 PRO A CG    1 
ATOM   1662  C CD    . PRO A 1 399 ? 100.679 182.042 204.243 1.00 44.04  ? 370 PRO A CD    1 
ATOM   1663  N N     . SER A 1 400 ? 103.710 184.154 204.987 1.00 40.51  ? 371 SER A N     1 
ATOM   1664  C CA    . SER A 1 400 ? 104.816 184.891 205.594 1.00 40.51  ? 371 SER A CA    1 
ATOM   1665  C C     . SER A 1 400 ? 106.165 184.365 205.119 1.00 40.51  ? 371 SER A C     1 
ATOM   1666  O O     . SER A 1 400 ? 107.062 185.149 204.780 1.00 40.51  ? 371 SER A O     1 
ATOM   1667  C CB    . SER A 1 400 ? 104.721 184.811 207.116 1.00 40.51  ? 371 SER A CB    1 
ATOM   1668  O OG    . SER A 1 400 ? 105.933 185.222 207.723 1.00 40.51  ? 371 SER A OG    1 
ATOM   1669  N N     . GLU A 1 401 ? 106.328 183.041 205.089 1.00 41.90  ? 372 GLU A N     1 
ATOM   1670  C CA    . GLU A 1 401 ? 107.591 182.463 204.647 1.00 41.90  ? 372 GLU A CA    1 
ATOM   1671  C C     . GLU A 1 401 ? 107.827 182.729 203.166 1.00 41.90  ? 372 GLU A C     1 
ATOM   1672  O O     . GLU A 1 401 ? 108.961 182.990 202.749 1.00 41.90  ? 372 GLU A O     1 
ATOM   1673  C CB    . GLU A 1 401 ? 107.605 180.965 204.945 1.00 41.90  ? 372 GLU A CB    1 
ATOM   1674  C CG    . GLU A 1 401 ? 107.762 180.656 206.425 1.00 41.90  ? 372 GLU A CG    1 
ATOM   1675  C CD    . GLU A 1 401 ? 107.753 179.173 206.722 1.00 41.90  ? 372 GLU A CD    1 
ATOM   1676  O OE1   . GLU A 1 401 ? 107.759 178.375 205.766 1.00 41.90  ? 372 GLU A OE1   1 
ATOM   1677  O OE2   . GLU A 1 401 ? 107.740 178.803 207.915 1.00 41.90  ? 372 GLU A OE2   1 
ATOM   1678  N N     . MET A 1 402 ? 106.765 182.688 202.360 1.00 40.25  ? 373 MET A N     1 
ATOM   1679  C CA    . MET A 1 402 ? 106.903 183.018 200.946 1.00 40.25  ? 373 MET A CA    1 
ATOM   1680  C C     . MET A 1 402 ? 107.287 184.480 200.755 1.00 40.25  ? 373 MET A C     1 
ATOM   1681  O O     . MET A 1 402 ? 108.109 184.800 199.889 1.00 40.25  ? 373 MET A O     1 
ATOM   1682  C CB    . MET A 1 402 ? 105.605 182.701 200.206 1.00 40.25  ? 373 MET A CB    1 
ATOM   1683  C CG    . MET A 1 402 ? 105.762 182.622 198.698 1.00 40.25  ? 373 MET A CG    1 
ATOM   1684  S SD    . MET A 1 402 ? 104.337 181.884 197.883 1.00 40.25  ? 373 MET A SD    1 
ATOM   1685  C CE    . MET A 1 402 ? 104.587 180.151 198.251 1.00 40.25  ? 373 MET A CE    1 
ATOM   1686  N N     . ILE A 1 403 ? 106.704 185.381 201.552 1.00 41.12  ? 374 ILE A N     1 
ATOM   1687  C CA    . ILE A 1 403 ? 107.051 186.798 201.452 1.00 41.12  ? 374 ILE A CA    1 
ATOM   1688  C C     . ILE A 1 403 ? 108.508 187.009 201.845 1.00 41.12  ? 374 ILE A C     1 
ATOM   1689  O O     . ILE A 1 403 ? 109.220 187.812 201.231 1.00 41.12  ? 374 ILE A O     1 
ATOM   1690  C CB    . ILE A 1 403 ? 106.095 187.651 202.311 1.00 41.12  ? 374 ILE A CB    1 
ATOM   1691  C CG1   . ILE A 1 403 ? 104.693 187.686 201.689 1.00 41.12  ? 374 ILE A CG1   1 
ATOM   1692  C CG2   . ILE A 1 403 ? 106.607 189.090 202.458 1.00 41.12  ? 374 ILE A CG2   1 
ATOM   1693  C CD1   . ILE A 1 403 ? 103.577 187.956 202.684 1.00 41.12  ? 374 ILE A CD1   1 
ATOM   1694  N N     . GLN A 1 404 ? 108.976 186.288 202.866 1.00 38.03  ? 375 GLN A N     1 
ATOM   1695  C CA    . GLN A 1 404 ? 110.385 186.372 203.241 1.00 38.03  ? 375 GLN A CA    1 
ATOM   1696  C C     . GLN A 1 404 ? 111.287 185.839 202.132 1.00 38.03  ? 375 GLN A C     1 
ATOM   1697  O O     . GLN A 1 404 ? 112.376 186.376 201.896 1.00 38.03  ? 375 GLN A O     1 
ATOM   1698  C CB    . GLN A 1 404 ? 110.623 185.609 204.543 1.00 38.03  ? 375 GLN A CB    1 
ATOM   1699  C CG    . GLN A 1 404 ? 110.090 186.324 205.770 1.00 38.03  ? 375 GLN A CG    1 
ATOM   1700  C CD    . GLN A 1 404 ? 109.978 185.414 206.973 1.00 38.03  ? 375 GLN A CD    1 
ATOM   1701  O OE1   . GLN A 1 404 ? 110.975 185.096 207.618 1.00 38.03  ? 375 GLN A OE1   1 
ATOM   1702  N NE2   . GLN A 1 404 ? 108.759 184.991 207.285 1.00 38.03  ? 375 GLN A NE2   1 
ATOM   1703  N N     . ILE A 1 405 ? 110.844 184.787 201.439 1.00 36.78  ? 376 ILE A N     1 
ATOM   1704  C CA    . ILE A 1 405 ? 111.628 184.215 200.343 1.00 36.78  ? 376 ILE A CA    1 
ATOM   1705  C C     . ILE A 1 405 ? 111.764 185.229 199.211 1.00 36.78  ? 376 ILE A C     1 
ATOM   1706  O O     . ILE A 1 405 ? 112.860 185.450 198.674 1.00 36.78  ? 376 ILE A O     1 
ATOM   1707  C CB    . ILE A 1 405 ? 110.978 182.898 199.869 1.00 36.78  ? 376 ILE A CB    1 
ATOM   1708  C CG1   . ILE A 1 405 ? 111.436 181.756 200.771 1.00 36.78  ? 376 ILE A CG1   1 
ATOM   1709  C CG2   . ILE A 1 405 ? 111.341 182.537 198.412 1.00 36.78  ? 376 ILE A CG2   1 
ATOM   1710  C CD1   . ILE A 1 405 ? 110.496 180.562 200.821 1.00 36.78  ? 376 ILE A CD1   1 
ATOM   1711  N N     . ILE A 1 406 ? 110.647 185.850 198.824 1.00 37.17  ? 377 ILE A N     1 
ATOM   1712  C CA    . ILE A 1 406 ? 110.694 186.855 197.763 1.00 37.17  ? 377 ILE A CA    1 
ATOM   1713  C C     . ILE A 1 406 ? 111.500 188.070 198.201 1.00 37.17  ? 377 ILE A C     1 
ATOM   1714  O O     . ILE A 1 406 ? 112.193 188.680 197.381 1.00 37.17  ? 377 ILE A O     1 
ATOM   1715  C CB    . ILE A 1 406 ? 109.279 187.263 197.298 1.00 37.17  ? 377 ILE A CB    1 
ATOM   1716  C CG1   . ILE A 1 406 ? 108.446 186.059 196.810 1.00 37.17  ? 377 ILE A CG1   1 
ATOM   1717  C CG2   . ILE A 1 406 ? 109.364 188.346 196.226 1.00 37.17  ? 377 ILE A CG2   1 
ATOM   1718  C CD1   . ILE A 1 406 ? 108.945 185.373 195.537 1.00 37.17  ? 377 ILE A CD1   1 
ATOM   1719  N N     . ALA A 1 407 ? 111.436 188.443 199.481 1.00 38.60  ? 378 ALA A N     1 
ATOM   1720  C CA    . ALA A 1 407 ? 112.247 189.557 199.962 1.00 38.60  ? 378 ALA A CA    1 
ATOM   1721  C C     . ALA A 1 407 ? 113.735 189.240 199.872 1.00 38.60  ? 378 ALA A C     1 
ATOM   1722  O O     . ALA A 1 407 ? 114.536 190.095 199.473 1.00 38.60  ? 378 ALA A O     1 
ATOM   1723  C CB    . ALA A 1 407 ? 111.861 189.903 201.399 1.00 38.60  ? 378 ALA A CB    1 
ATOM   1724  N N     . ILE A 1 408 ? 114.122 188.011 200.230 1.00 35.77  ? 379 ILE A N     1 
ATOM   1725  C CA    . ILE A 1 408 ? 115.528 187.616 200.155 1.00 35.77  ? 379 ILE A CA    1 
ATOM   1726  C C     . ILE A 1 408 ? 116.000 187.619 198.708 1.00 35.77  ? 379 ILE A C     1 
ATOM   1727  O O     . ILE A 1 408 ? 117.095 188.106 198.397 1.00 35.77  ? 379 ILE A O     1 
ATOM   1728  C CB    . ILE A 1 408 ? 115.736 186.239 200.822 1.00 35.77  ? 379 ILE A CB    1 
ATOM   1729  C CG1   . ILE A 1 408 ? 115.593 186.358 202.344 1.00 35.77  ? 379 ILE A CG1   1 
ATOM   1730  C CG2   . ILE A 1 408 ? 117.124 185.655 200.484 1.00 35.77  ? 379 ILE A CG2   1 
ATOM   1731  C CD1   . ILE A 1 408 ? 115.277 185.058 203.047 1.00 35.77  ? 379 ILE A CD1   1 
ATOM   1732  N N     . ARG A 1 409 ? 115.160 187.084 197.812 1.00 36.20  ? 380 ARG A N     1 
ATOM   1733  C CA    . ARG A 1 409 ? 115.504 187.003 196.370 1.00 36.20  ? 380 ARG A CA    1 
ATOM   1734  C C     . ARG A 1 409 ? 115.588 188.417 195.781 1.00 36.20  ? 380 ARG A C     1 
ATOM   1735  O O     . ARG A 1 409 ? 116.444 188.614 194.902 1.00 36.20  ? 380 ARG A O     1 
ATOM   1736  C CB    . ARG A 1 409 ? 114.469 186.197 195.576 1.00 36.20  ? 380 ARG A CB    1 
ATOM   1737  C CG    . ARG A 1 409 ? 114.708 184.694 195.515 1.00 36.20  ? 380 ARG A CG    1 
ATOM   1738  C CD    . ARG A 1 409 ? 116.133 184.322 195.125 1.00 36.20  ? 380 ARG A CD    1 
ATOM   1739  N NE    . ARG A 1 409 ? 116.626 184.980 193.910 1.00 36.20  ? 380 ARG A NE    1 
ATOM   1740  C CZ    . ARG A 1 409 ? 117.868 184.880 193.448 1.00 36.20  ? 380 ARG A CZ    1 
ATOM   1741  N NH1   . ARG A 1 409 ? 118.704 183.981 193.942 1.00 36.20  ? 380 ARG A NH1   1 
ATOM   1742  N NH2   . ARG A 1 409 ? 118.270 185.679 192.477 1.00 36.20  ? 380 ARG A NH2   1 
ATOM   1743  N N     . ALA A 1 410 ? 114.734 189.348 196.220 1.00 40.15  ? 381 ALA A N     1 
ATOM   1744  C CA    . ALA A 1 410 ? 114.778 190.723 195.735 1.00 40.15  ? 381 ALA A CA    1 
ATOM   1745  C C     . ALA A 1 410 ? 116.018 191.447 196.240 1.00 40.15  ? 381 ALA A C     1 
ATOM   1746  O O     . ALA A 1 410 ? 116.652 192.198 195.491 1.00 40.15  ? 381 ALA A O     1 
ATOM   1747  C CB    . ALA A 1 410 ? 113.514 191.469 196.159 1.00 40.15  ? 381 ALA A CB    1 
ATOM   1748  N N     . GLN A 1 411 ? 116.375 191.241 197.511 1.00 39.11  ? 382 GLN A N     1 
ATOM   1749  C CA    . GLN A 1 411 ? 117.576 191.870 198.050 1.00 39.11  ? 382 GLN A CA    1 
ATOM   1750  C C     . GLN A 1 411 ? 118.833 191.343 197.369 1.00 39.11  ? 382 GLN A C     1 
ATOM   1751  O O     . GLN A 1 411 ? 119.761 192.109 197.087 1.00 39.11  ? 382 GLN A O     1 
ATOM   1752  C CB    . GLN A 1 411 ? 117.655 191.643 199.559 1.00 39.11  ? 382 GLN A CB    1 
ATOM   1753  C CG    . GLN A 1 411 ? 118.807 192.380 200.227 1.00 39.11  ? 382 GLN A CG    1 
ATOM   1754  C CD    . GLN A 1 411 ? 118.607 192.571 201.719 1.00 39.11  ? 382 GLN A CD    1 
ATOM   1755  O OE1   . GLN A 1 411 ? 117.724 191.965 202.325 1.00 39.11  ? 382 GLN A OE1   1 
ATOM   1756  N NE2   . GLN A 1 411 ? 119.436 193.416 202.319 1.00 39.11  ? 382 GLN A NE2   1 
ATOM   1757  N N     . VAL A 1 412 ? 118.883 190.037 197.101 1.00 37.23  ? 383 VAL A N     1 
ATOM   1758  C CA    . VAL A 1 412 ? 120.064 189.457 196.468 1.00 37.23  ? 383 VAL A CA    1 
ATOM   1759  C C     . VAL A 1 412 ? 120.180 189.908 195.016 1.00 37.23  ? 383 VAL A C     1 
ATOM   1760  O O     . VAL A 1 412 ? 121.288 189.984 194.472 1.00 37.23  ? 383 VAL A O     1 
ATOM   1761  C CB    . VAL A 1 412 ? 120.019 187.922 196.613 1.00 37.23  ? 383 VAL A CB    1 
ATOM   1762  C CG1   . VAL A 1 412 ? 121.061 187.227 195.710 1.00 37.23  ? 383 VAL A CG1   1 
ATOM   1763  C CG2   . VAL A 1 412 ? 120.203 187.533 198.094 1.00 37.23  ? 383 VAL A CG2   1 
ATOM   1764  N N     . GLU A 1 413 ? 119.058 190.221 194.366 1.00 40.02  ? 384 GLU A N     1 
ATOM   1765  C CA    . GLU A 1 413 ? 119.069 190.764 193.011 1.00 40.02  ? 384 GLU A CA    1 
ATOM   1766  C C     . GLU A 1 413 ? 119.400 192.255 192.954 1.00 40.02  ? 384 GLU A C     1 
ATOM   1767  O O     . GLU A 1 413 ? 119.408 192.816 191.853 1.00 40.02  ? 384 GLU A O     1 
ATOM   1768  C CB    . GLU A 1 413 ? 117.708 190.523 192.347 1.00 40.02  ? 384 GLU A CB    1 
ATOM   1769  C CG    . GLU A 1 413 ? 117.399 189.064 192.055 1.00 40.02  ? 384 GLU A CG    1 
ATOM   1770  C CD    . GLU A 1 413 ? 117.601 188.706 190.598 1.00 40.02  ? 384 GLU A CD    1 
ATOM   1771  O OE1   . GLU A 1 413 ? 118.718 188.917 190.082 1.00 40.02  ? 384 GLU A OE1   1 
ATOM   1772  O OE2   . GLU A 1 413 ? 116.641 188.213 189.969 1.00 40.02  ? 384 GLU A OE2   1 
ATOM   1773  N N     . GLU A 1 414 ? 119.691 192.902 194.091 1.00 44.81  ? 385 GLU A N     1 
ATOM   1774  C CA    . GLU A 1 414 ? 119.885 194.354 194.172 1.00 44.81  ? 385 GLU A CA    1 
ATOM   1775  C C     . GLU A 1 414 ? 118.643 195.094 193.667 1.00 44.81  ? 385 GLU A C     1 
ATOM   1776  O O     . GLU A 1 414 ? 118.720 196.022 192.857 1.00 44.81  ? 385 GLU A O     1 
ATOM   1777  C CB    . GLU A 1 414 ? 121.157 194.793 193.430 1.00 44.81  ? 385 GLU A CB    1 
ATOM   1778  C CG    . GLU A 1 414 ? 122.433 194.494 194.196 1.00 44.81  ? 385 GLU A CG    1 
ATOM   1779  C CD    . GLU A 1 414 ? 122.711 195.520 195.277 1.00 44.81  ? 385 GLU A CD    1 
ATOM   1780  O OE1   . GLU A 1 414 ? 122.100 195.423 196.362 1.00 44.81  ? 385 GLU A OE1   1 
ATOM   1781  O OE2   . GLU A 1 414 ? 123.540 196.424 195.041 1.00 44.81  ? 385 GLU A OE2   1 
ATOM   1782  N N     . LEU A 1 415 ? 117.482 194.650 194.152 1.00 45.97  ? 386 LEU A N     1 
ATOM   1783  C CA    . LEU A 1 415 ? 116.195 195.298 193.925 1.00 45.97  ? 386 LEU A CA    1 
ATOM   1784  C C     . LEU A 1 415 ? 115.674 195.837 195.249 1.00 45.97  ? 386 LEU A C     1 
ATOM   1785  O O     . LEU A 1 415 ? 115.686 195.126 196.259 1.00 45.97  ? 386 LEU A O     1 
ATOM   1786  C CB    . LEU A 1 415 ? 115.179 194.323 193.326 1.00 45.97  ? 386 LEU A CB    1 
ATOM   1787  C CG    . LEU A 1 415 ? 115.090 194.245 191.801 1.00 45.97  ? 386 LEU A CG    1 
ATOM   1788  C CD1   . LEU A 1 415 ? 116.462 194.110 191.167 1.00 45.97  ? 386 LEU A CD1   1 
ATOM   1789  C CD2   . LEU A 1 415 ? 114.200 193.085 191.398 1.00 45.97  ? 386 LEU A CD2   1 
ATOM   1790  N N     . THR A 1 416 ? 115.214 197.086 195.234 1.00 54.63  ? 387 THR A N     1 
ATOM   1791  C CA    . THR A 1 416 ? 114.657 197.748 196.408 1.00 54.63  ? 387 THR A CA    1 
ATOM   1792  C C     . THR A 1 416 ? 113.140 197.611 196.370 1.00 54.63  ? 387 THR A C     1 
ATOM   1793  O O     . THR A 1 416 ? 112.500 198.040 195.404 1.00 54.63  ? 387 THR A O     1 
ATOM   1794  C CB    . THR A 1 416 ? 115.065 199.220 196.448 1.00 54.63  ? 387 THR A CB    1 
ATOM   1795  O OG1   . THR A 1 416 ? 114.299 199.958 195.489 1.00 54.63  ? 387 THR A OG1   1 
ATOM   1796  C CG2   . THR A 1 416 ? 116.547 199.373 196.134 1.00 54.63  ? 387 THR A CG2   1 
ATOM   1797  N N     . VAL A 1 417 ? 112.574 197.017 197.425 1.00 52.11  ? 388 VAL A N     1 
ATOM   1798  C CA    . VAL A 1 417 ? 111.156 196.694 197.514 1.00 52.11  ? 388 VAL A CA    1 
ATOM   1799  C C     . VAL A 1 417 ? 110.623 197.173 198.858 1.00 52.11  ? 388 VAL A C     1 
ATOM   1800  O O     . VAL A 1 417 ? 111.379 197.493 199.778 1.00 52.11  ? 388 VAL A O     1 
ATOM   1801  C CB    . VAL A 1 417 ? 110.885 195.178 197.338 1.00 52.11  ? 388 VAL A CB    1 
ATOM   1802  C CG1   . VAL A 1 417 ? 111.012 194.772 195.878 1.00 52.11  ? 388 VAL A CG1   1 
ATOM   1803  C CG2   . VAL A 1 417 ? 111.826 194.328 198.207 1.00 52.11  ? 388 VAL A CG2   1 
ATOM   1804  N N     . ASP A 1 418 ? 109.295 197.222 198.949 1.00 58.89  ? 389 ASP A N     1 
ATOM   1805  C CA    . ASP A 1 418 ? 108.555 197.557 200.158 1.00 58.89  ? 389 ASP A CA    1 
ATOM   1806  C C     . ASP A 1 418 ? 107.609 196.412 200.500 1.00 58.89  ? 389 ASP A C     1 
ATOM   1807  O O     . ASP A 1 418 ? 107.363 195.516 199.691 1.00 58.89  ? 389 ASP A O     1 
ATOM   1808  C CB    . ASP A 1 418 ? 107.779 198.874 199.991 1.00 58.89  ? 389 ASP A CB    1 
ATOM   1809  C CG    . ASP A 1 418 ? 106.959 198.926 198.708 1.00 58.89  ? 389 ASP A CG    1 
ATOM   1810  O OD1   . ASP A 1 418 ? 106.113 198.035 198.487 1.00 58.89  ? 389 ASP A OD1   1 
ATOM   1811  O OD2   . ASP A 1 418 ? 107.165 199.869 197.916 1.00 58.89  ? 389 ASP A OD2   1 
ATOM   1812  N N     . GLU A 1 419 ? 107.076 196.451 201.723 1.00 61.16  ? 390 GLU A N     1 
ATOM   1813  C CA    . GLU A 1 419 ? 106.180 195.389 202.174 1.00 61.16  ? 390 GLU A CA    1 
ATOM   1814  C C     . GLU A 1 419 ? 104.883 195.354 201.372 1.00 61.16  ? 390 GLU A C     1 
ATOM   1815  O O     . GLU A 1 419 ? 104.290 194.279 201.206 1.00 61.16  ? 390 GLU A O     1 
ATOM   1816  C CB    . GLU A 1 419 ? 105.877 195.555 203.667 1.00 61.16  ? 390 GLU A CB    1 
ATOM   1817  C CG    . GLU A 1 419 ? 105.145 196.850 204.059 1.00 61.16  ? 390 GLU A CG    1 
ATOM   1818  C CD    . GLU A 1 419 ? 103.635 196.692 204.140 1.00 61.16  ? 390 GLU A CD    1 
ATOM   1819  O OE1   . GLU A 1 419 ? 103.159 195.750 204.808 1.00 61.16  ? 390 GLU A OE1   1 
ATOM   1820  O OE2   . GLU A 1 419 ? 102.922 197.518 203.533 1.00 61.16  ? 390 GLU A OE2   1 
ATOM   1821  N N     . GLU A 1 420 ? 104.437 196.509 200.863 1.00 59.85  ? 391 GLU A N     1 
ATOM   1822  C CA    . GLU A 1 420 ? 103.152 196.593 200.170 1.00 59.85  ? 391 GLU A CA    1 
ATOM   1823  C C     . GLU A 1 420 ? 103.146 195.741 198.905 1.00 59.85  ? 391 GLU A C     1 
ATOM   1824  O O     . GLU A 1 420 ? 102.229 194.940 198.690 1.00 59.85  ? 391 GLU A O     1 
ATOM   1825  C CB    . GLU A 1 420 ? 102.835 198.062 199.854 1.00 59.85  ? 391 GLU A CB    1 
ATOM   1826  C CG    . GLU A 1 420 ? 101.835 198.311 198.709 1.00 59.85  ? 391 GLU A CG    1 
ATOM   1827  C CD    . GLU A 1 420 ? 101.304 199.737 198.670 1.00 59.85  ? 391 GLU A CD    1 
ATOM   1828  O OE1   . GLU A 1 420 ? 101.162 200.373 199.737 1.00 59.85  ? 391 GLU A OE1   1 
ATOM   1829  O OE2   . GLU A 1 420 ? 101.027 200.228 197.556 1.00 59.85  ? 391 GLU A OE2   1 
ATOM   1830  N N     . CYS A 1 421 ? 104.167 195.894 198.059 1.00 56.25  ? 392 CYS A N     1 
ATOM   1831  C CA    . CYS A 1 421 ? 104.260 195.073 196.858 1.00 56.25  ? 392 CYS A CA    1 
ATOM   1832  C C     . CYS A 1 421 ? 104.728 193.656 197.169 1.00 56.25  ? 392 CYS A C     1 
ATOM   1833  O O     . CYS A 1 421 ? 104.426 192.729 196.410 1.00 56.25  ? 392 CYS A O     1 
ATOM   1834  C CB    . CYS A 1 421 ? 105.203 195.724 195.846 1.00 56.25  ? 392 CYS A CB    1 
ATOM   1835  S SG    . CYS A 1 421 ? 106.951 195.453 196.173 1.00 56.25  ? 392 CYS A SG    1 
ATOM   1836  N N     . LEU A 1 422 ? 105.466 193.464 198.266 1.00 49.52  ? 393 LEU A N     1 
ATOM   1837  C CA    . LEU A 1 422 ? 105.888 192.118 198.636 1.00 49.52  ? 393 LEU A CA    1 
ATOM   1838  C C     . LEU A 1 422 ? 104.708 191.251 199.048 1.00 49.52  ? 393 LEU A C     1 
ATOM   1839  O O     . LEU A 1 422 ? 104.732 190.038 198.820 1.00 49.52  ? 393 LEU A O     1 
ATOM   1840  C CB    . LEU A 1 422 ? 106.919 192.173 199.762 1.00 49.52  ? 393 LEU A CB    1 
ATOM   1841  C CG    . LEU A 1 422 ? 108.357 192.537 199.378 1.00 49.52  ? 393 LEU A CG    1 
ATOM   1842  C CD1   . LEU A 1 422 ? 109.175 192.834 200.627 1.00 49.52  ? 393 LEU A CD1   1 
ATOM   1843  C CD2   . LEU A 1 422 ? 109.021 191.431 198.565 1.00 49.52  ? 393 LEU A CD2   1 
ATOM   1844  N N     . VAL A 1 423 ? 103.674 191.841 199.656 1.00 50.18  ? 394 VAL A N     1 
ATOM   1845  C CA    . VAL A 1 423 ? 102.464 191.076 199.955 1.00 50.18  ? 394 VAL A CA    1 
ATOM   1846  C C     . VAL A 1 423 ? 101.811 190.596 198.661 1.00 50.18  ? 394 VAL A C     1 
ATOM   1847  O O     . VAL A 1 423 ? 101.360 189.447 198.562 1.00 50.18  ? 394 VAL A O     1 
ATOM   1848  C CB    . VAL A 1 423 ? 101.498 191.918 200.814 1.00 50.18  ? 394 VAL A CB    1 
ATOM   1849  C CG1   . VAL A 1 423 ? 100.091 191.301 200.860 1.00 50.18  ? 394 VAL A CG1   1 
ATOM   1850  C CG2   . VAL A 1 423 ? 102.039 192.057 202.230 1.00 50.18  ? 394 VAL A CG2   1 
ATOM   1851  N N     . LEU A 1 424 ? 101.757 191.465 197.649 1.00 49.03  ? 395 LEU A N     1 
ATOM   1852  C CA    . LEU A 1 424 ? 101.194 191.070 196.362 1.00 49.03  ? 395 LEU A CA    1 
ATOM   1853  C C     . LEU A 1 424 ? 102.039 189.991 195.695 1.00 49.03  ? 395 LEU A C     1 
ATOM   1854  O O     . LEU A 1 424 ? 101.500 189.071 195.070 1.00 49.03  ? 395 LEU A O     1 
ATOM   1855  C CB    . LEU A 1 424 ? 101.069 192.294 195.454 1.00 49.03  ? 395 LEU A CB    1 
ATOM   1856  C CG    . LEU A 1 424 ? 100.472 192.106 194.053 1.00 49.03  ? 395 LEU A CG    1 
ATOM   1857  C CD1   . LEU A 1 424 ? 99.066  191.527 194.114 1.00 49.03  ? 395 LEU A CD1   1 
ATOM   1858  C CD2   . LEU A 1 424 ? 100.461 193.416 193.294 1.00 49.03  ? 395 LEU A CD2   1 
ATOM   1859  N N     . LEU A 1 425 ? 103.364 190.097 195.801 1.00 45.01  ? 396 LEU A N     1 
ATOM   1860  C CA    . LEU A 1 425 ? 104.230 189.074 195.221 1.00 45.01  ? 396 LEU A CA    1 
ATOM   1861  C C     . LEU A 1 425 ? 104.059 187.740 195.938 1.00 45.01  ? 396 LEU A C     1 
ATOM   1862  O O     . LEU A 1 425 ? 104.089 186.681 195.302 1.00 45.01  ? 396 LEU A O     1 
ATOM   1863  C CB    . LEU A 1 425 ? 105.692 189.524 195.262 1.00 45.01  ? 396 LEU A CB    1 
ATOM   1864  C CG    . LEU A 1 425 ? 106.181 190.419 194.114 1.00 45.01  ? 396 LEU A CG    1 
ATOM   1865  C CD1   . LEU A 1 425 ? 107.560 190.989 194.415 1.00 45.01  ? 396 LEU A CD1   1 
ATOM   1866  C CD2   . LEU A 1 425 ? 106.215 189.668 192.784 1.00 45.01  ? 396 LEU A CD2   1 
ATOM   1867  N N     . GLY A 1 426 ? 103.876 187.772 197.258 1.00 44.26  ? 397 GLY A N     1 
ATOM   1868  C CA    . GLY A 1 426 ? 103.562 186.550 197.979 1.00 44.26  ? 397 GLY A CA    1 
ATOM   1869  C C     . GLY A 1 426 ? 102.236 185.953 197.549 1.00 44.26  ? 397 GLY A C     1 
ATOM   1870  O O     . GLY A 1 426 ? 102.101 184.732 197.442 1.00 44.26  ? 397 GLY A O     1 
ATOM   1871  N N     . GLU A 1 427 ? 101.242 186.807 197.292 1.00 47.24  ? 398 GLU A N     1 
ATOM   1872  C CA    . GLU A 1 427 ? 99.956  186.327 196.786 1.00 47.24  ? 398 GLU A CA    1 
ATOM   1873  C C     . GLU A 1 427 ? 100.118 185.672 195.416 1.00 47.24  ? 398 GLU A C     1 
ATOM   1874  O O     . GLU A 1 427 ? 99.537  184.611 195.152 1.00 47.24  ? 398 GLU A O     1 
ATOM   1875  C CB    . GLU A 1 427 ? 98.957  187.495 196.742 1.00 47.24  ? 398 GLU A CB    1 
ATOM   1876  C CG    . GLU A 1 427 ? 97.744  187.372 195.798 1.00 47.24  ? 398 GLU A CG    1 
ATOM   1877  C CD    . GLU A 1 427 ? 96.909  186.132 196.055 1.00 47.24  ? 398 GLU A CD    1 
ATOM   1878  O OE1   . GLU A 1 427 ? 96.611  185.848 197.233 1.00 47.24  ? 398 GLU A OE1   1 
ATOM   1879  O OE2   . GLU A 1 427 ? 96.548  185.446 195.076 1.00 47.24  ? 398 GLU A OE2   1 
ATOM   1880  N N     . ILE A 1 428 ? 100.909 186.291 194.536 1.00 44.95  ? 399 ILE A N     1 
ATOM   1881  C CA    . ILE A 1 428 ? 101.113 185.748 193.194 1.00 44.95  ? 399 ILE A CA    1 
ATOM   1882  C C     . ILE A 1 428 ? 101.859 184.422 193.269 1.00 44.95  ? 399 ILE A C     1 
ATOM   1883  O O     . ILE A 1 428 ? 101.567 183.487 192.515 1.00 44.95  ? 399 ILE A O     1 
ATOM   1884  C CB    . ILE A 1 428 ? 101.852 186.769 192.304 1.00 44.95  ? 399 ILE A CB    1 
ATOM   1885  C CG1   . ILE A 1 428 ? 100.959 187.976 191.987 1.00 44.95  ? 399 ILE A CG1   1 
ATOM   1886  C CG2   . ILE A 1 428 ? 102.308 186.132 190.985 1.00 44.95  ? 399 ILE A CG2   1 
ATOM   1887  C CD1   . ILE A 1 428 ? 101.731 189.249 191.699 1.00 44.95  ? 399 ILE A CD1   1 
ATOM   1888  N N     . GLY A 1 429 ? 102.842 184.325 194.165 1.00 40.72  ? 400 GLY A N     1 
ATOM   1889  C CA    . GLY A 1 429 ? 103.535 183.062 194.350 1.00 40.72  ? 400 GLY A CA    1 
ATOM   1890  C C     . GLY A 1 429 ? 102.631 181.979 194.904 1.00 40.72  ? 400 GLY A C     1 
ATOM   1891  O O     . GLY A 1 429 ? 102.698 180.823 194.478 1.00 40.72  ? 400 GLY A O     1 
ATOM   1892  N N     . GLN A 1 430 ? 101.773 182.335 195.862 1.00 43.52  ? 401 GLN A N     1 
ATOM   1893  C CA    . GLN A 1 430 ? 100.855 181.360 196.436 1.00 43.52  ? 401 GLN A CA    1 
ATOM   1894  C C     . GLN A 1 430 ? 99.819  180.898 195.422 1.00 43.52  ? 401 GLN A C     1 
ATOM   1895  O O     . GLN A 1 430 ? 99.348  179.758 195.497 1.00 43.52  ? 401 GLN A O     1 
ATOM   1896  C CB    . GLN A 1 430 ? 100.164 181.952 197.663 1.00 43.52  ? 401 GLN A CB    1 
ATOM   1897  C CG    . GLN A 1 430 ? 101.054 182.048 198.890 1.00 43.52  ? 401 GLN A CG    1 
ATOM   1898  C CD    . GLN A 1 430 ? 100.312 181.746 200.175 1.00 43.52  ? 401 GLN A CD    1 
ATOM   1899  O OE1   . GLN A 1 430 ? 100.905 181.307 201.159 1.00 43.52  ? 401 GLN A OE1   1 
ATOM   1900  N NE2   . GLN A 1 430 ? 99.006  181.983 200.173 1.00 43.52  ? 401 GLN A NE2   1 
ATOM   1901  N N     . ARG A 1 431 ? 99.452  181.757 194.473 1.00 46.83  ? 402 ARG A N     1 
ATOM   1902  C CA    . ARG A 1 431 ? 98.429  181.394 193.502 1.00 46.83  ? 402 ARG A CA    1 
ATOM   1903  C C     . ARG A 1 431 ? 98.970  180.578 192.335 1.00 46.83  ? 402 ARG A C     1 
ATOM   1904  O O     . ARG A 1 431 ? 98.268  179.690 191.839 1.00 46.83  ? 402 ARG A O     1 
ATOM   1905  C CB    . ARG A 1 431 ? 97.734  182.651 192.970 1.00 46.83  ? 402 ARG A CB    1 
ATOM   1906  C CG    . ARG A 1 431 ? 97.093  182.476 191.604 1.00 46.83  ? 402 ARG A CG    1 
ATOM   1907  C CD    . ARG A 1 431 ? 96.074  183.568 191.330 1.00 46.83  ? 402 ARG A CD    1 
ATOM   1908  N NE    . ARG A 1 431 ? 96.679  184.894 191.337 1.00 46.83  ? 402 ARG A NE    1 
ATOM   1909  C CZ    . ARG A 1 431 ? 97.463  185.362 190.376 1.00 46.83  ? 402 ARG A CZ    1 
ATOM   1910  N NH1   . ARG A 1 431 ? 97.757  184.637 189.310 1.00 46.83  ? 402 ARG A NH1   1 
ATOM   1911  N NH2   . ARG A 1 431 ? 97.962  186.590 190.487 1.00 46.83  ? 402 ARG A NH2   1 
ATOM   1912  N N     . THR A 1 432 ? 100.197 180.843 191.883 1.00 40.13  ? 403 THR A N     1 
ATOM   1913  C CA    . THR A 1 432 ? 100.759 180.136 190.738 1.00 40.13  ? 403 THR A CA    1 
ATOM   1914  C C     . THR A 1 432 ? 101.942 179.254 191.118 1.00 40.13  ? 403 THR A C     1 
ATOM   1915  O O     . THR A 1 432 ? 101.883 178.036 190.931 1.00 40.13  ? 403 THR A O     1 
ATOM   1916  C CB    . THR A 1 432 ? 101.180 181.140 189.657 1.00 40.13  ? 403 THR A CB    1 
ATOM   1917  O OG1   . THR A 1 432 ? 102.222 181.981 190.165 1.00 40.13  ? 403 THR A OG1   1 
ATOM   1918  C CG2   . THR A 1 432 ? 100.001 182.001 189.246 1.00 40.13  ? 403 THR A CG2   1 
ATOM   1919  N N     . SER A 1 433 ? 103.008 179.834 191.665 1.00 37.14  ? 404 SER A N     1 
ATOM   1920  C CA    . SER A 1 433 ? 104.203 179.093 192.055 1.00 37.14  ? 404 SER A CA    1 
ATOM   1921  C C     . SER A 1 433 ? 105.192 180.070 192.670 1.00 37.14  ? 404 SER A C     1 
ATOM   1922  O O     . SER A 1 433 ? 105.109 181.282 192.454 1.00 37.14  ? 404 SER A O     1 
ATOM   1923  C CB    . SER A 1 433 ? 104.855 178.373 190.870 1.00 37.14  ? 404 SER A CB    1 
ATOM   1924  O OG    . SER A 1 433 ? 104.827 179.176 189.705 1.00 37.14  ? 404 SER A OG    1 
ATOM   1925  N N     . LEU A 1 434 ? 106.137 179.525 193.436 1.00 33.05  ? 405 LEU A N     1 
ATOM   1926  C CA    . LEU A 1 434 ? 107.201 180.354 193.990 1.00 33.05  ? 405 LEU A CA    1 
ATOM   1927  C C     . LEU A 1 434 ? 108.204 180.752 192.915 1.00 33.05  ? 405 LEU A C     1 
ATOM   1928  O O     . LEU A 1 434 ? 108.739 181.867 192.940 1.00 33.05  ? 405 LEU A O     1 
ATOM   1929  C CB    . LEU A 1 434 ? 107.897 179.616 195.131 1.00 33.05  ? 405 LEU A CB    1 
ATOM   1930  C CG    . LEU A 1 434 ? 108.957 180.387 195.915 1.00 33.05  ? 405 LEU A CG    1 
ATOM   1931  C CD1   . LEU A 1 434 ? 108.559 181.838 196.060 1.00 33.05  ? 405 LEU A CD1   1 
ATOM   1932  C CD2   . LEU A 1 434 ? 109.163 179.752 197.274 1.00 33.05  ? 405 LEU A CD2   1 
ATOM   1933  N N     . ARG A 1 435 ? 108.472 179.848 191.967 1.00 37.14  ? 406 ARG A N     1 
ATOM   1934  C CA    . ARG A 1 435 ? 109.425 180.137 190.899 1.00 37.14  ? 406 ARG A CA    1 
ATOM   1935  C C     . ARG A 1 435 ? 108.947 181.286 190.027 1.00 37.14  ? 406 ARG A C     1 
ATOM   1936  O O     . ARG A 1 435 ? 109.744 182.141 189.623 1.00 37.14  ? 406 ARG A O     1 
ATOM   1937  C CB    . ARG A 1 435 ? 109.650 178.891 190.049 1.00 37.14  ? 406 ARG A CB    1 
ATOM   1938  C CG    . ARG A 1 435 ? 110.352 177.789 190.795 1.00 37.14  ? 406 ARG A CG    1 
ATOM   1939  C CD    . ARG A 1 435 ? 110.698 176.592 189.917 1.00 37.14  ? 406 ARG A CD    1 
ATOM   1940  N NE    . ARG A 1 435 ? 112.063 176.127 190.145 1.00 37.14  ? 406 ARG A NE    1 
ATOM   1941  C CZ    . ARG A 1 435 ? 112.680 175.174 189.456 1.00 37.14  ? 406 ARG A CZ    1 
ATOM   1942  N NH1   . ARG A 1 435 ? 112.069 174.490 188.498 1.00 37.14  ? 406 ARG A NH1   1 
ATOM   1943  N NH2   . ARG A 1 435 ? 113.948 174.892 189.739 1.00 37.14  ? 406 ARG A NH2   1 
ATOM   1944  N N     . HIS A 1 436 ? 107.648 181.318 189.720 1.00 38.37  ? 407 HIS A N     1 
ATOM   1945  C CA    . HIS A 1 436 ? 107.104 182.409 188.921 1.00 38.37  ? 407 HIS A CA    1 
ATOM   1946  C C     . HIS A 1 436 ? 107.237 183.740 189.648 1.00 38.37  ? 407 HIS A C     1 
ATOM   1947  O O     . HIS A 1 436 ? 107.634 184.744 189.047 1.00 38.37  ? 407 HIS A O     1 
ATOM   1948  C CB    . HIS A 1 436 ? 105.643 182.126 188.581 1.00 38.37  ? 407 HIS A CB    1 
ATOM   1949  C CG    . HIS A 1 436 ? 104.997 183.198 187.763 1.00 38.37  ? 407 HIS A CG    1 
ATOM   1950  N ND1   . HIS A 1 436 ? 105.200 183.321 186.406 1.00 38.37  ? 407 HIS A ND1   1 
ATOM   1951  C CD2   . HIS A 1 436 ? 104.149 184.194 188.108 1.00 38.37  ? 407 HIS A CD2   1 
ATOM   1952  C CE1   . HIS A 1 436 ? 104.508 184.349 185.951 1.00 38.37  ? 407 HIS A CE1   1 
ATOM   1953  N NE2   . HIS A 1 436 ? 103.860 184.896 186.964 1.00 38.37  ? 407 HIS A NE2   1 
ATOM   1954  N N     . ALA A 1 437 ? 106.933 183.761 190.948 1.00 36.26  ? 408 ALA A N     1 
ATOM   1955  C CA    . ALA A 1 437 ? 107.042 184.996 191.716 1.00 36.26  ? 408 ALA A CA    1 
ATOM   1956  C C     . ALA A 1 437 ? 108.486 185.469 191.802 1.00 36.26  ? 408 ALA A C     1 
ATOM   1957  O O     . ALA A 1 437 ? 108.754 186.675 191.757 1.00 36.26  ? 408 ALA A O     1 
ATOM   1958  C CB    . ALA A 1 437 ? 106.461 184.796 193.114 1.00 36.26  ? 408 ALA A CB    1 
ATOM   1959  N N     . VAL A 1 438 ? 109.431 184.536 191.925 1.00 35.30  ? 409 VAL A N     1 
ATOM   1960  C CA    . VAL A 1 438 ? 110.840 184.919 191.936 1.00 35.30  ? 409 VAL A CA    1 
ATOM   1961  C C     . VAL A 1 438 ? 111.253 185.467 190.573 1.00 35.30  ? 409 VAL A C     1 
ATOM   1962  O O     . VAL A 1 438 ? 111.995 186.452 190.489 1.00 35.30  ? 409 VAL A O     1 
ATOM   1963  C CB    . VAL A 1 438 ? 111.715 183.726 192.369 1.00 35.30  ? 409 VAL A CB    1 
ATOM   1964  C CG1   . VAL A 1 438 ? 113.201 183.996 192.107 1.00 35.30  ? 409 VAL A CG1   1 
ATOM   1965  C CG2   . VAL A 1 438 ? 111.499 183.423 193.848 1.00 35.30  ? 409 VAL A CG2   1 
ATOM   1966  N N     . GLN A 1 439 ? 110.782 184.847 189.487 1.00 38.15  ? 410 GLN A N     1 
ATOM   1967  C CA    . GLN A 1 439 ? 111.202 185.265 188.153 1.00 38.15  ? 410 GLN A CA    1 
ATOM   1968  C C     . GLN A 1 439 ? 110.548 186.568 187.706 1.00 38.15  ? 410 GLN A C     1 
ATOM   1969  O O     . GLN A 1 439 ? 111.079 187.229 186.809 1.00 38.15  ? 410 GLN A O     1 
ATOM   1970  C CB    . GLN A 1 439 ? 110.936 184.137 187.139 1.00 38.15  ? 410 GLN A CB    1 
ATOM   1971  C CG    . GLN A 1 439 ? 109.686 184.255 186.255 1.00 38.15  ? 410 GLN A CG    1 
ATOM   1972  C CD    . GLN A 1 439 ? 109.405 182.973 185.498 1.00 38.15  ? 410 GLN A CD    1 
ATOM   1973  O OE1   . GLN A 1 439 ? 110.300 182.156 185.288 1.00 38.15  ? 410 GLN A OE1   1 
ATOM   1974  N NE2   . GLN A 1 439 ? 108.159 182.793 185.080 1.00 38.15  ? 410 GLN A NE2   1 
ATOM   1975  N N     . LEU A 1 440 ? 109.417 186.956 188.302 1.00 40.80  ? 411 LEU A N     1 
ATOM   1976  C CA    . LEU A 1 440 ? 108.797 188.235 187.955 1.00 40.80  ? 411 LEU A CA    1 
ATOM   1977  C C     . LEU A 1 440 ? 109.581 189.450 188.453 1.00 40.80  ? 411 LEU A C     1 
ATOM   1978  O O     . LEU A 1 440 ? 109.251 190.572 188.054 1.00 40.80  ? 411 LEU A O     1 
ATOM   1979  C CB    . LEU A 1 440 ? 107.372 188.314 188.520 1.00 40.80  ? 411 LEU A CB    1 
ATOM   1980  C CG    . LEU A 1 440 ? 106.214 187.507 187.914 1.00 40.80  ? 411 LEU A CG    1 
ATOM   1981  C CD1   . LEU A 1 440 ? 105.001 187.644 188.815 1.00 40.80  ? 411 LEU A CD1   1 
ATOM   1982  C CD2   . LEU A 1 440 ? 105.840 187.907 186.507 1.00 40.80  ? 411 LEU A CD2   1 
ATOM   1983  N N     . LEU A 1 441 ? 110.594 189.269 189.309 1.00 40.89  ? 412 LEU A N     1 
ATOM   1984  C CA    . LEU A 1 441 ? 111.230 190.408 189.966 1.00 40.89  ? 412 LEU A CA    1 
ATOM   1985  C C     . LEU A 1 441 ? 112.034 191.261 188.990 1.00 40.89  ? 412 LEU A C     1 
ATOM   1986  O O     . LEU A 1 441 ? 112.007 192.493 189.074 1.00 40.89  ? 412 LEU A O     1 
ATOM   1987  C CB    . LEU A 1 441 ? 112.129 189.916 191.100 1.00 40.89  ? 412 LEU A CB    1 
ATOM   1988  C CG    . LEU A 1 441 ? 111.435 189.476 192.393 1.00 40.89  ? 412 LEU A CG    1 
ATOM   1989  C CD1   . LEU A 1 441 ? 112.401 188.688 193.266 1.00 40.89  ? 412 LEU A CD1   1 
ATOM   1990  C CD2   . LEU A 1 441 ? 110.872 190.666 193.162 1.00 40.89  ? 412 LEU A CD2   1 
ATOM   1991  N N     . SER A 1 442 ? 112.785 190.632 188.085 1.00 45.17  ? 413 SER A N     1 
ATOM   1992  C CA    . SER A 1 442 ? 113.590 191.399 187.133 1.00 45.17  ? 413 SER A CA    1 
ATOM   1993  C C     . SER A 1 442 ? 112.746 192.243 186.184 1.00 45.17  ? 413 SER A C     1 
ATOM   1994  O O     . SER A 1 442 ? 113.036 193.447 186.045 1.00 45.17  ? 413 SER A O     1 
ATOM   1995  C CB    . SER A 1 442 ? 114.516 190.453 186.360 1.00 45.17  ? 413 SER A CB    1 
ATOM   1996  O OG    . SER A 1 442 ? 115.694 190.183 187.097 1.00 45.17  ? 413 SER A OG    1 
ATOM   1997  N N     . PRO A 1 443 ? 111.722 191.709 185.502 1.00 43.87  ? 414 PRO A N     1 
ATOM   1998  C CA    . PRO A 1 443 ? 110.855 192.598 184.711 1.00 43.87  ? 414 PRO A CA    1 
ATOM   1999  C C     . PRO A 1 443 ? 110.105 193.620 185.546 1.00 43.87  ? 414 PRO A C     1 
ATOM   2000  O O     . PRO A 1 443 ? 109.760 194.685 185.024 1.00 43.87  ? 414 PRO A O     1 
ATOM   2001  C CB    . PRO A 1 443 ? 109.897 191.629 184.003 1.00 43.87  ? 414 PRO A CB    1 
ATOM   2002  C CG    . PRO A 1 443 ? 110.045 190.337 184.693 1.00 43.87  ? 414 PRO A CG    1 
ATOM   2003  C CD    . PRO A 1 443 ? 111.437 190.295 185.200 1.00 43.87  ? 414 PRO A CD    1 
ATOM   2004  N N     . ALA A 1 444 ? 109.852 193.344 186.827 1.00 48.38  ? 415 ALA A N     1 
ATOM   2005  C CA    . ALA A 1 444 ? 109.293 194.376 187.693 1.00 48.38  ? 415 ALA A CA    1 
ATOM   2006  C C     . ALA A 1 444 ? 110.271 195.528 187.868 1.00 48.38  ? 415 ALA A C     1 
ATOM   2007  O O     . ALA A 1 444 ? 109.872 196.697 187.845 1.00 48.38  ? 415 ALA A O     1 
ATOM   2008  C CB    . ALA A 1 444 ? 108.903 193.784 189.045 1.00 48.38  ? 415 ALA A CB    1 
ATOM   2009  N N     . SER A 1 445 ? 111.560 195.218 188.027 1.00 49.36  ? 416 SER A N     1 
ATOM   2010  C CA    . SER A 1 445 ? 112.569 196.269 188.100 1.00 49.36  ? 416 SER A CA    1 
ATOM   2011  C C     . SER A 1 445 ? 112.645 197.048 186.794 1.00 49.36  ? 416 SER A C     1 
ATOM   2012  O O     . SER A 1 445 ? 112.801 198.275 186.803 1.00 49.36  ? 416 SER A O     1 
ATOM   2013  C CB    . SER A 1 445 ? 113.930 195.667 188.440 1.00 49.36  ? 416 SER A CB    1 
ATOM   2014  O OG    . SER A 1 445 ? 114.891 196.684 188.657 1.00 49.36  ? 416 SER A OG    1 
ATOM   2015  N N     . ILE A 1 446 ? 112.531 196.352 185.661 1.00 48.48  ? 417 ILE A N     1 
ATOM   2016  C CA    . ILE A 1 446 ? 112.574 197.031 184.367 1.00 48.48  ? 417 ILE A CA    1 
ATOM   2017  C C     . ILE A 1 446 ? 111.369 197.952 184.197 1.00 48.48  ? 417 ILE A C     1 
ATOM   2018  O O     . ILE A 1 446 ? 111.501 199.080 183.706 1.00 48.48  ? 417 ILE A O     1 
ATOM   2019  C CB    . ILE A 1 446 ? 112.668 195.996 183.228 1.00 48.48  ? 417 ILE A CB    1 
ATOM   2020  C CG1   . ILE A 1 446 ? 114.002 195.221 183.276 1.00 48.48  ? 417 ILE A CG1   1 
ATOM   2021  C CG2   . ILE A 1 446 ? 112.448 196.648 181.856 1.00 48.48  ? 417 ILE A CG2   1 
ATOM   2022  C CD1   . ILE A 1 446 ? 115.289 196.039 183.078 1.00 48.48  ? 417 ILE A CD1   1 
ATOM   2023  N N     . VAL A 1 447 ? 110.178 197.487 184.578 1.00 51.94  ? 418 VAL A N     1 
ATOM   2024  C CA    . VAL A 1 447 ? 108.986 198.318 184.449 1.00 51.94  ? 418 VAL A CA    1 
ATOM   2025  C C     . VAL A 1 447 ? 109.057 199.499 185.409 1.00 51.94  ? 418 VAL A C     1 
ATOM   2026  O O     . VAL A 1 447 ? 108.570 200.591 185.092 1.00 51.94  ? 418 VAL A O     1 
ATOM   2027  C CB    . VAL A 1 447 ? 107.722 197.459 184.664 1.00 51.94  ? 418 VAL A CB    1 
ATOM   2028  C CG1   . VAL A 1 447 ? 106.477 198.317 184.964 1.00 51.94  ? 418 VAL A CG1   1 
ATOM   2029  C CG2   . VAL A 1 447 ? 107.483 196.580 183.444 1.00 51.94  ? 418 VAL A CG2   1 
ATOM   2030  N N     . ALA A 1 448 ? 109.641 199.305 186.594 1.00 55.50  ? 419 ALA A N     1 
ATOM   2031  C CA    . ALA A 1 448 ? 109.851 200.426 187.503 1.00 55.50  ? 419 ALA A CA    1 
ATOM   2032  C C     . ALA A 1 448 ? 110.809 201.445 186.902 1.00 55.50  ? 419 ALA A C     1 
ATOM   2033  O O     . ALA A 1 448 ? 110.596 202.657 187.023 1.00 55.50  ? 419 ALA A O     1 
ATOM   2034  C CB    . ALA A 1 448 ? 110.378 199.918 188.844 1.00 55.50  ? 419 ALA A CB    1 
ATOM   2035  N N     . LYS A 1 449 ? 111.872 200.971 186.248 1.00 57.14  ? 420 LYS A N     1 
ATOM   2036  C CA    . LYS A 1 449 ? 112.801 201.882 185.587 1.00 57.14  ? 420 LYS A CA    1 
ATOM   2037  C C     . LYS A 1 449 ? 112.139 202.620 184.431 1.00 57.14  ? 420 LYS A C     1 
ATOM   2038  O O     . LYS A 1 449 ? 112.478 203.779 184.166 1.00 57.14  ? 420 LYS A O     1 
ATOM   2039  C CB    . LYS A 1 449 ? 114.026 201.113 185.076 1.00 57.14  ? 420 LYS A CB    1 
ATOM   2040  C CG    . LYS A 1 449 ? 115.117 200.766 186.123 1.00 57.14  ? 420 LYS A CG    1 
ATOM   2041  C CD    . LYS A 1 449 ? 115.672 201.933 186.973 1.00 57.14  ? 420 LYS A CD    1 
ATOM   2042  C CE    . LYS A 1 449 ? 116.124 203.191 186.210 1.00 57.14  ? 420 LYS A CE    1 
ATOM   2043  N NZ    . LYS A 1 449 ? 116.597 203.012 184.807 1.00 57.14  ? 420 LYS A NZ    1 
ATOM   2044  N N     . MET A 1 450 ? 111.210 201.969 183.727 1.00 57.42  ? 421 MET A N     1 
ATOM   2045  C CA    . MET A 1 450 ? 110.499 202.640 182.642 1.00 57.42  ? 421 MET A CA    1 
ATOM   2046  C C     . MET A 1 450 ? 109.642 203.784 183.168 1.00 57.42  ? 421 MET A C     1 
ATOM   2047  O O     . MET A 1 450 ? 109.502 204.817 182.503 1.00 57.42  ? 421 MET A O     1 
ATOM   2048  C CB    . MET A 1 450 ? 109.633 201.640 181.872 1.00 57.42  ? 421 MET A CB    1 
ATOM   2049  C CG    . MET A 1 450 ? 110.358 200.959 180.700 1.00 57.42  ? 421 MET A CG    1 
ATOM   2050  S SD    . MET A 1 450 ? 109.415 199.861 179.595 1.00 57.42  ? 421 MET A SD    1 
ATOM   2051  C CE    . MET A 1 450 ? 107.746 200.518 179.594 1.00 57.42  ? 421 MET A CE    1 
ATOM   2052  N N     . ASN A 1 451 ? 109.066 203.622 184.359 1.00 60.00  ? 422 ASN A N     1 
ATOM   2053  C CA    . ASN A 1 451 ? 108.242 204.648 184.989 1.00 60.00  ? 422 ASN A CA    1 
ATOM   2054  C C     . ASN A 1 451 ? 109.061 205.685 185.767 1.00 60.00  ? 422 ASN A C     1 
ATOM   2055  O O     . ASN A 1 451 ? 108.479 206.467 186.526 1.00 60.00  ? 422 ASN A O     1 
ATOM   2056  C CB    . ASN A 1 451 ? 107.216 203.980 185.911 1.00 60.00  ? 422 ASN A CB    1 
ATOM   2057  C CG    . ASN A 1 451 ? 106.155 203.222 185.141 1.00 60.00  ? 422 ASN A CG    1 
ATOM   2058  O OD1   . ASN A 1 451 ? 106.434 202.627 184.101 1.00 60.00  ? 422 ASN A OD1   1 
ATOM   2059  N ND2   . ASN A 1 451 ? 104.928 203.238 185.650 1.00 60.00  ? 422 ASN A ND2   1 
ATOM   2060  N N     . GLY A 1 452 ? 110.378 205.730 185.590 1.00 63.13  ? 423 GLY A N     1 
ATOM   2061  C CA    . GLY A 1 452 ? 111.187 206.733 186.260 1.00 63.13  ? 423 GLY A CA    1 
ATOM   2062  C C     . GLY A 1 452 ? 111.248 206.592 187.765 1.00 63.13  ? 423 GLY A C     1 
ATOM   2063  O O     . GLY A 1 452 ? 111.113 207.593 188.481 1.00 63.13  ? 423 GLY A O     1 
ATOM   2064  N N     . ARG A 1 453 ? 111.438 205.373 188.265 1.00 60.30  ? 424 ARG A N     1 
ATOM   2065  C CA    . ARG A 1 453 ? 111.609 205.144 189.692 1.00 60.30  ? 424 ARG A CA    1 
ATOM   2066  C C     . ARG A 1 453 ? 112.463 203.903 189.899 1.00 60.30  ? 424 ARG A C     1 
ATOM   2067  O O     . ARG A 1 453 ? 112.343 202.922 189.161 1.00 60.30  ? 424 ARG A O     1 
ATOM   2068  C CB    . ARG A 1 453 ? 110.263 204.982 190.408 1.00 60.30  ? 424 ARG A CB    1 
ATOM   2069  C CG    . ARG A 1 453 ? 109.322 203.962 189.778 1.00 60.30  ? 424 ARG A CG    1 
ATOM   2070  C CD    . ARG A 1 453 ? 108.091 203.741 190.639 1.00 60.30  ? 424 ARG A CD    1 
ATOM   2071  N NE    . ARG A 1 453 ? 107.046 203.019 189.910 1.00 60.30  ? 424 ARG A NE    1 
ATOM   2072  C CZ    . ARG A 1 453 ? 105.886 203.507 189.477 1.00 60.30  ? 424 ARG A CZ    1 
ATOM   2073  N NH1   . ARG A 1 453 ? 105.552 204.784 189.620 1.00 60.30  ? 424 ARG A NH1   1 
ATOM   2074  N NH2   . ARG A 1 453 ? 105.034 202.690 188.864 1.00 60.30  ? 424 ARG A NH2   1 
ATOM   2075  N N     . ASP A 1 454 ? 113.328 203.958 190.914 1.00 63.59  ? 425 ASP A N     1 
ATOM   2076  C CA    . ASP A 1 454 ? 114.132 202.795 191.272 1.00 63.59  ? 425 ASP A CA    1 
ATOM   2077  C C     . ASP A 1 454 ? 113.324 201.784 192.075 1.00 63.59  ? 425 ASP A C     1 
ATOM   2078  O O     . ASP A 1 454 ? 113.482 200.572 191.890 1.00 63.59  ? 425 ASP A O     1 
ATOM   2079  C CB    . ASP A 1 454 ? 115.366 203.231 192.062 1.00 63.59  ? 425 ASP A CB    1 
ATOM   2080  C CG    . ASP A 1 454 ? 116.299 204.113 191.253 1.00 63.59  ? 425 ASP A CG    1 
ATOM   2081  O OD1   . ASP A 1 454 ? 116.119 204.209 190.021 1.00 63.59  ? 425 ASP A OD1   1 
ATOM   2082  O OD2   . ASP A 1 454 ? 117.219 204.708 191.852 1.00 63.59  ? 425 ASP A OD2   1 
ATOM   2083  N N     . ASN A 1 455 ? 112.456 202.258 192.965 1.00 60.40  ? 426 ASN A N     1 
ATOM   2084  C CA    . ASN A 1 455 ? 111.671 201.356 193.793 1.00 60.40  ? 426 ASN A CA    1 
ATOM   2085  C C     . ASN A 1 455 ? 110.614 200.643 192.958 1.00 60.40  ? 426 ASN A C     1 
ATOM   2086  O O     . ASN A 1 455 ? 110.058 201.201 192.008 1.00 60.40  ? 426 ASN A O     1 
ATOM   2087  C CB    . ASN A 1 455 ? 111.009 202.119 194.942 1.00 60.40  ? 426 ASN A CB    1 
ATOM   2088  C CG    . ASN A 1 455 ? 109.765 202.871 194.505 1.00 60.40  ? 426 ASN A CG    1 
ATOM   2089  O OD1   . ASN A 1 455 ? 109.792 203.618 193.530 1.00 60.40  ? 426 ASN A OD1   1 
ATOM   2090  N ND2   . ASN A 1 455 ? 108.666 202.674 195.225 1.00 60.40  ? 426 ASN A ND2   1 
ATOM   2091  N N     . ILE A 1 456 ? 110.347 199.391 193.324 1.00 53.74  ? 427 ILE A N     1 
ATOM   2092  C CA    . ILE A 1 456 ? 109.351 198.565 192.651 1.00 53.74  ? 427 ILE A CA    1 
ATOM   2093  C C     . ILE A 1 456 ? 108.029 198.835 193.365 1.00 53.74  ? 427 ILE A C     1 
ATOM   2094  O O     . ILE A 1 456 ? 107.798 198.355 194.475 1.00 53.74  ? 427 ILE A O     1 
ATOM   2095  C CB    . ILE A 1 456 ? 109.747 197.084 192.671 1.00 53.74  ? 427 ILE A CB    1 
ATOM   2096  C CG1   . ILE A 1 456 ? 110.793 196.840 191.571 1.00 53.74  ? 427 ILE A CG1   1 
ATOM   2097  C CG2   . ILE A 1 456 ? 108.503 196.152 192.488 1.00 53.74  ? 427 ILE A CG2   1 
ATOM   2098  C CD1   . ILE A 1 456 ? 111.473 195.470 191.579 1.00 53.74  ? 427 ILE A CD1   1 
ATOM   2099  N N     . CYS A 1 457 ? 107.160 199.610 192.723 1.00 59.02  ? 428 CYS A N     1 
ATOM   2100  C CA    . CYS A 1 457 ? 105.857 199.920 193.287 1.00 59.02  ? 428 CYS A CA    1 
ATOM   2101  C C     . CYS A 1 457 ? 104.901 198.746 193.090 1.00 59.02  ? 428 CYS A C     1 
ATOM   2102  O O     . CYS A 1 457 ? 105.195 197.779 192.382 1.00 59.02  ? 428 CYS A O     1 
ATOM   2103  C CB    . CYS A 1 457 ? 105.283 201.184 192.650 1.00 59.02  ? 428 CYS A CB    1 
ATOM   2104  S SG    . CYS A 1 457 ? 103.499 201.380 192.873 1.00 59.02  ? 428 CYS A SG    1 
ATOM   2105  N N     . LYS A 1 458 ? 103.740 198.836 193.741 1.00 56.75  ? 429 LYS A N     1 
ATOM   2106  C CA    . LYS A 1 458 ? 102.721 197.803 193.588 1.00 56.75  ? 429 LYS A CA    1 
ATOM   2107  C C     . LYS A 1 458 ? 102.188 197.763 192.161 1.00 56.75  ? 429 LYS A C     1 
ATOM   2108  O O     . LYS A 1 458 ? 101.932 196.680 191.617 1.00 56.75  ? 429 LYS A O     1 
ATOM   2109  C CB    . LYS A 1 458 ? 101.583 198.046 194.578 1.00 56.75  ? 429 LYS A CB    1 
ATOM   2110  C CG    . LYS A 1 458 ? 100.524 196.948 194.599 1.00 56.75  ? 429 LYS A CG    1 
ATOM   2111  C CD    . LYS A 1 458 ? 99.588  197.055 195.803 1.00 56.75  ? 429 LYS A CD    1 
ATOM   2112  C CE    . LYS A 1 458 ? 98.622  198.231 195.691 1.00 56.75  ? 429 LYS A CE    1 
ATOM   2113  N NZ    . LYS A 1 458 ? 97.812  198.406 196.927 1.00 56.75  ? 429 LYS A NZ    1 
ATOM   2114  N N     . ALA A 1 459 ? 102.017 198.936 191.542 1.00 54.94  ? 430 ALA A N     1 
ATOM   2115  C CA    . ALA A 1 459 ? 101.520 199.000 190.170 1.00 54.94  ? 430 ALA A CA    1 
ATOM   2116  C C     . ALA A 1 459 ? 102.476 198.329 189.195 1.00 54.94  ? 430 ALA A C     1 
ATOM   2117  O O     . ALA A 1 459 ? 102.035 197.757 188.191 1.00 54.94  ? 430 ALA A O     1 
ATOM   2118  C CB    . ALA A 1 459 ? 101.287 200.455 189.764 1.00 54.94  ? 430 ALA A CB    1 
ATOM   2119  N N     . ASP A 1 460 ? 103.781 198.375 189.480 1.00 54.17  ? 431 ASP A N     1 
ATOM   2120  C CA    . ASP A 1 460 ? 104.747 197.654 188.658 1.00 54.17  ? 431 ASP A CA    1 
ATOM   2121  C C     . ASP A 1 460 ? 104.486 196.154 188.707 1.00 54.17  ? 431 ASP A C     1 
ATOM   2122  O O     . ASP A 1 460 ? 104.467 195.483 187.668 1.00 54.17  ? 431 ASP A O     1 
ATOM   2123  C CB    . ASP A 1 460 ? 106.173 197.963 189.120 1.00 54.17  ? 431 ASP A CB    1 
ATOM   2124  C CG    . ASP A 1 460 ? 106.479 199.448 189.124 1.00 54.17  ? 431 ASP A CG    1 
ATOM   2125  O OD1   . ASP A 1 460 ? 106.062 200.145 188.177 1.00 54.17  ? 431 ASP A OD1   1 
ATOM   2126  O OD2   . ASP A 1 460 ? 107.136 199.918 190.077 1.00 54.17  ? 431 ASP A OD2   1 
ATOM   2127  N N     . ILE A 1 461 ? 104.253 195.620 189.911 1.00 49.59  ? 432 ILE A N     1 
ATOM   2128  C CA    . ILE A 1 461 ? 103.972 194.194 190.062 1.00 49.59  ? 432 ILE A CA    1 
ATOM   2129  C C     . ILE A 1 461 ? 102.681 193.828 189.347 1.00 49.59  ? 432 ILE A C     1 
ATOM   2130  O O     . ILE A 1 461 ? 102.607 192.785 188.686 1.00 49.59  ? 432 ILE A O     1 
ATOM   2131  C CB    . ILE A 1 461 ? 103.914 193.802 191.554 1.00 49.59  ? 432 ILE A CB    1 
ATOM   2132  C CG1   . ILE A 1 461 ? 105.241 194.093 192.283 1.00 49.59  ? 432 ILE A CG1   1 
ATOM   2133  C CG2   . ILE A 1 461 ? 103.501 192.329 191.705 1.00 49.59  ? 432 ILE A CG2   1 
ATOM   2134  C CD1   . ILE A 1 461 ? 106.480 193.393 191.737 1.00 49.59  ? 432 ILE A CD1   1 
ATOM   2135  N N     . GLU A 1 462 ? 101.646 194.674 189.470 1.00 50.31  ? 433 GLU A N     1 
ATOM   2136  C CA    . GLU A 1 462 ? 100.388 194.422 188.766 1.00 50.31  ? 433 GLU A CA    1 
ATOM   2137  C C     . GLU A 1 462 ? 100.592 194.387 187.257 1.00 50.31  ? 433 GLU A C     1 
ATOM   2138  O O     . GLU A 1 462 ? 100.062 193.502 186.574 1.00 50.31  ? 433 GLU A O     1 
ATOM   2139  C CB    . GLU A 1 462 ? 99.341  195.485 189.113 1.00 50.31  ? 433 GLU A CB    1 
ATOM   2140  C CG    . GLU A 1 462 ? 98.991  195.590 190.606 1.00 50.31  ? 433 GLU A CG    1 
ATOM   2141  C CD    . GLU A 1 462 ? 97.525  195.920 190.913 1.00 50.31  ? 433 GLU A CD    1 
ATOM   2142  O OE1   . GLU A 1 462 ? 97.193  196.008 192.114 1.00 50.31  ? 433 GLU A OE1   1 
ATOM   2143  O OE2   . GLU A 1 462 ? 96.704  196.114 189.991 1.00 50.31  ? 433 GLU A OE2   1 
ATOM   2144  N N     . GLU A 1 463 ? 101.383 195.325 186.728 1.00 49.61  ? 434 GLU A N     1 
ATOM   2145  C CA    . GLU A 1 463 ? 101.656 195.356 185.295 1.00 49.61  ? 434 GLU A CA    1 
ATOM   2146  C C     . GLU A 1 463 ? 102.376 194.092 184.844 1.00 49.61  ? 434 GLU A C     1 
ATOM   2147  O O     . GLU A 1 463 ? 102.003 193.477 183.836 1.00 49.61  ? 434 GLU A O     1 
ATOM   2148  C CB    . GLU A 1 463 ? 102.485 196.595 184.954 1.00 49.61  ? 434 GLU A CB    1 
ATOM   2149  C CG    . GLU A 1 463 ? 102.464 196.987 183.483 1.00 49.61  ? 434 GLU A CG    1 
ATOM   2150  C CD    . GLU A 1 463 ? 101.229 197.780 183.098 1.00 49.61  ? 434 GLU A CD    1 
ATOM   2151  O OE1   . GLU A 1 463 ? 100.239 197.763 183.859 1.00 49.61  ? 434 GLU A OE1   1 
ATOM   2152  O OE2   . GLU A 1 463 ? 101.251 198.423 182.029 1.00 49.61  ? 434 GLU A OE2   1 
ATOM   2153  N N     . VAL A 1 464 ? 103.393 193.668 185.598 1.00 46.21  ? 435 VAL A N     1 
ATOM   2154  C CA    . VAL A 1 464 ? 104.203 192.543 185.138 1.00 46.21  ? 435 VAL A CA    1 
ATOM   2155  C C     . VAL A 1 464 ? 103.411 191.240 185.233 1.00 46.21  ? 435 VAL A C     1 
ATOM   2156  O O     . VAL A 1 464 ? 103.464 190.416 184.313 1.00 46.21  ? 435 VAL A O     1 
ATOM   2157  C CB    . VAL A 1 464 ? 105.548 192.474 185.895 1.00 46.21  ? 435 VAL A CB    1 
ATOM   2158  C CG1   . VAL A 1 464 ? 106.458 191.353 185.352 1.00 46.21  ? 435 VAL A CG1   1 
ATOM   2159  C CG2   . VAL A 1 464 ? 106.307 193.794 185.764 1.00 46.21  ? 435 VAL A CG2   1 
ATOM   2160  N N     . THR A 1 465 ? 102.662 191.022 186.326 1.00 45.53  ? 436 THR A N     1 
ATOM   2161  C CA    . THR A 1 465 ? 101.877 189.785 186.383 1.00 45.53  ? 436 THR A CA    1 
ATOM   2162  C C     . THR A 1 465 ? 100.713 189.814 185.401 1.00 45.53  ? 436 THR A C     1 
ATOM   2163  O O     . THR A 1 465 ? 100.250 188.747 184.986 1.00 45.53  ? 436 THR A O     1 
ATOM   2164  C CB    . THR A 1 465 ? 101.308 189.457 187.776 1.00 45.53  ? 436 THR A CB    1 
ATOM   2165  O OG1   . THR A 1 465 ? 100.328 188.423 187.635 1.00 45.53  ? 436 THR A OG1   1 
ATOM   2166  C CG2   . THR A 1 465 ? 100.584 190.621 188.428 1.00 45.53  ? 436 THR A CG2   1 
ATOM   2167  N N     . SER A 1 466 ? 100.224 191.001 185.019 1.00 45.88  ? 437 SER A N     1 
ATOM   2168  C CA    . SER A 1 466 ? 99.245  191.064 183.941 1.00 45.88  ? 437 SER A CA    1 
ATOM   2169  C C     . SER A 1 466 ? 99.871  190.677 182.608 1.00 45.88  ? 437 SER A C     1 
ATOM   2170  O O     . SER A 1 466 ? 99.219  190.039 181.775 1.00 45.88  ? 437 SER A O     1 
ATOM   2171  C CB    . SER A 1 466 ? 98.638  192.464 183.862 1.00 45.88  ? 437 SER A CB    1 
ATOM   2172  O OG    . SER A 1 466 ? 99.531  193.375 183.249 1.00 45.88  ? 437 SER A OG    1 
ATOM   2173  N N     . LEU A 1 467 ? 101.133 191.055 182.385 1.00 45.71  ? 438 LEU A N     1 
ATOM   2174  C CA    . LEU A 1 467 ? 101.791 190.729 181.122 1.00 45.71  ? 438 LEU A CA    1 
ATOM   2175  C C     . LEU A 1 467 ? 102.201 189.260 181.064 1.00 45.71  ? 438 LEU A C     1 
ATOM   2176  O O     . LEU A 1 467 ? 101.708 188.500 180.223 1.00 45.71  ? 438 LEU A O     1 
ATOM   2177  C CB    . LEU A 1 467 ? 103.018 191.624 180.919 1.00 45.71  ? 438 LEU A CB    1 
ATOM   2178  C CG    . LEU A 1 467 ? 102.784 193.110 180.636 1.00 45.71  ? 438 LEU A CG    1 
ATOM   2179  C CD1   . LEU A 1 467 ? 104.100 193.869 180.709 1.00 45.71  ? 438 LEU A CD1   1 
ATOM   2180  C CD2   . LEU A 1 467 ? 102.118 193.326 179.286 1.00 45.71  ? 438 LEU A CD2   1 
ATOM   2181  N N     . TYR A 1 468 ? 103.093 188.842 181.960 1.00 43.09  ? 439 TYR A N     1 
ATOM   2182  C CA    . TYR A 1 468 ? 103.710 187.517 181.911 1.00 43.09  ? 439 TYR A CA    1 
ATOM   2183  C C     . TYR A 1 468 ? 102.889 186.549 182.751 1.00 43.09  ? 439 TYR A C     1 
ATOM   2184  O O     . TYR A 1 468 ? 103.022 186.502 183.975 1.00 43.09  ? 439 TYR A O     1 
ATOM   2185  C CB    . TYR A 1 468 ? 105.149 187.586 182.408 1.00 43.09  ? 439 TYR A CB    1 
ATOM   2186  C CG    . TYR A 1 468 ? 106.019 188.570 181.660 1.00 43.09  ? 439 TYR A CG    1 
ATOM   2187  C CD1   . TYR A 1 468 ? 106.101 188.546 180.277 1.00 43.09  ? 439 TYR A CD1   1 
ATOM   2188  C CD2   . TYR A 1 468 ? 106.786 189.501 182.340 1.00 43.09  ? 439 TYR A CD2   1 
ATOM   2189  C CE1   . TYR A 1 468 ? 106.897 189.432 179.596 1.00 43.09  ? 439 TYR A CE1   1 
ATOM   2190  C CE2   . TYR A 1 468 ? 107.583 190.396 181.663 1.00 43.09  ? 439 TYR A CE2   1 
ATOM   2191  C CZ    . TYR A 1 468 ? 107.635 190.354 180.292 1.00 43.09  ? 439 TYR A CZ    1 
ATOM   2192  O OH    . TYR A 1 468 ? 108.429 191.239 179.606 1.00 43.09  ? 439 TYR A OH    1 
ATOM   2193  N N     . LEU A 1 469 ? 102.043 185.767 182.089 1.00 42.99  ? 440 LEU A N     1 
ATOM   2194  C CA    . LEU A 1 469 ? 101.327 184.691 182.753 1.00 42.99  ? 440 LEU A CA    1 
ATOM   2195  C C     . LEU A 1 469 ? 102.265 183.521 183.016 1.00 42.99  ? 440 LEU A C     1 
ATOM   2196  O O     . LEU A 1 469 ? 103.254 183.320 182.306 1.00 42.99  ? 440 LEU A O     1 
ATOM   2197  C CB    . LEU A 1 469 ? 100.150 184.216 181.900 1.00 42.99  ? 440 LEU A CB    1 
ATOM   2198  C CG    . LEU A 1 469 ? 99.100  185.253 181.498 1.00 42.99  ? 440 LEU A CG    1 
ATOM   2199  C CD1   . LEU A 1 469 ? 98.087  184.637 180.550 1.00 42.99  ? 440 LEU A CD1   1 
ATOM   2200  C CD2   . LEU A 1 469 ? 98.400  185.823 182.720 1.00 42.99  ? 440 LEU A CD2   1 
ATOM   2201  N N     . ASP A 1 470 ? 101.947 182.746 184.049 1.00 43.67  ? 441 ASP A N     1 
ATOM   2202  C CA    . ASP A 1 470 ? 102.634 181.482 184.270 1.00 43.67  ? 441 ASP A CA    1 
ATOM   2203  C C     . ASP A 1 470 ? 102.165 180.462 183.234 1.00 43.67  ? 441 ASP A C     1 
ATOM   2204  O O     . ASP A 1 470 ? 101.287 180.731 182.409 1.00 43.67  ? 441 ASP A O     1 
ATOM   2205  C CB    . ASP A 1 470 ? 102.400 180.977 185.693 1.00 43.67  ? 441 ASP A CB    1 
ATOM   2206  C CG    . ASP A 1 470 ? 100.940 180.710 185.990 1.00 43.67  ? 441 ASP A CG    1 
ATOM   2207  O OD1   . ASP A 1 470 ? 100.080 181.335 185.338 1.00 43.67  ? 441 ASP A OD1   1 
ATOM   2208  O OD2   . ASP A 1 470 ? 100.655 179.878 186.876 1.00 43.67  ? 441 ASP A OD2   1 
ATOM   2209  N N     . ALA A 1 471 ? 102.771 179.274 183.271 1.00 44.41  ? 442 ALA A N     1 
ATOM   2210  C CA    . ALA A 1 471 ? 102.462 178.248 182.279 1.00 44.41  ? 442 ALA A CA    1 
ATOM   2211  C C     . ALA A 1 471 ? 101.023 177.764 182.395 1.00 44.41  ? 442 ALA A C     1 
ATOM   2212  O O     . ALA A 1 471 ? 100.358 177.527 181.380 1.00 44.41  ? 442 ALA A O     1 
ATOM   2213  C CB    . ALA A 1 471 ? 103.424 177.073 182.426 1.00 44.41  ? 442 ALA A CB    1 
ATOM   2214  N N     . LYS A 1 472 ? 100.520 177.629 183.620 1.00 48.00  ? 443 LYS A N     1 
ATOM   2215  C CA    . LYS A 1 472 ? 99.219  177.000 183.811 1.00 48.00  ? 443 LYS A CA    1 
ATOM   2216  C C     . LYS A 1 472 ? 98.094  177.922 183.361 1.00 48.00  ? 443 LYS A C     1 
ATOM   2217  O O     . LYS A 1 472 ? 97.171  177.487 182.664 1.00 48.00  ? 443 LYS A O     1 
ATOM   2218  C CB    . LYS A 1 472 ? 99.045  176.590 185.276 1.00 48.00  ? 443 LYS A CB    1 
ATOM   2219  C CG    . LYS A 1 472 ? 99.910  175.394 185.709 1.00 48.00  ? 443 LYS A CG    1 
ATOM   2220  C CD    . LYS A 1 472 ? 101.272 175.814 186.294 1.00 48.00  ? 443 LYS A CD    1 
ATOM   2221  C CE    . LYS A 1 472 ? 102.378 174.790 186.043 1.00 48.00  ? 443 LYS A CE    1 
ATOM   2222  N NZ    . LYS A 1 472 ? 103.725 175.366 186.311 1.00 48.00  ? 443 LYS A NZ    1 
ATOM   2223  N N     . SER A 1 473 ? 98.162  179.205 183.728 1.00 44.98  ? 444 SER A N     1 
ATOM   2224  C CA    . SER A 1 473 ? 97.145  180.155 183.287 1.00 44.98  ? 444 SER A CA    1 
ATOM   2225  C C     . SER A 1 473 ? 97.203  180.361 181.779 1.00 44.98  ? 444 SER A C     1 
ATOM   2226  O O     . SER A 1 473 ? 96.162  180.519 181.128 1.00 44.98  ? 444 SER A O     1 
ATOM   2227  C CB    . SER A 1 473 ? 97.319  181.487 184.014 1.00 44.98  ? 444 SER A CB    1 
ATOM   2228  O OG    . SER A 1 473 ? 97.299  181.310 185.420 1.00 44.98  ? 444 SER A OG    1 
ATOM   2229  N N     . SER A 1 474 ? 98.410  180.366 181.209 1.00 45.10  ? 445 SER A N     1 
ATOM   2230  C CA    . SER A 1 474 ? 98.545  180.479 179.761 1.00 45.10  ? 445 SER A CA    1 
ATOM   2231  C C     . SER A 1 474 ? 97.920  179.282 179.057 1.00 45.10  ? 445 SER A C     1 
ATOM   2232  O O     . SER A 1 474 ? 97.244  179.438 178.034 1.00 45.10  ? 445 SER A O     1 
ATOM   2233  C CB    . SER A 1 474 ? 100.018 180.613 179.382 1.00 45.10  ? 445 SER A CB    1 
ATOM   2234  O OG    . SER A 1 474 ? 100.166 180.861 177.996 1.00 45.10  ? 445 SER A OG    1 
ATOM   2235  N N     . ALA A 1 475 ? 98.119  178.078 179.596 1.00 46.88  ? 446 ALA A N     1 
ATOM   2236  C CA    . ALA A 1 475 ? 97.491  176.905 179.001 1.00 46.88  ? 446 ALA A CA    1 
ATOM   2237  C C     . ALA A 1 475 ? 95.980  176.919 179.176 1.00 46.88  ? 446 ALA A C     1 
ATOM   2238  O O     . ALA A 1 475 ? 95.259  176.425 178.305 1.00 46.88  ? 446 ALA A O     1 
ATOM   2239  C CB    . ALA A 1 475 ? 98.072  175.628 179.595 1.00 46.88  ? 446 ALA A CB    1 
ATOM   2240  N N     . LYS A 1 476 ? 95.479  177.454 180.293 1.00 48.56  ? 447 LYS A N     1 
ATOM   2241  C CA    . LYS A 1 476 ? 94.033  177.588 180.446 1.00 48.56  ? 447 LYS A CA    1 
ATOM   2242  C C     . LYS A 1 476 ? 93.464  178.567 179.426 1.00 48.56  ? 447 LYS A C     1 
ATOM   2243  O O     . LYS A 1 476 ? 92.372  178.345 178.891 1.00 48.56  ? 447 LYS A O     1 
ATOM   2244  C CB    . LYS A 1 476 ? 93.672  178.038 181.867 1.00 48.56  ? 447 LYS A CB    1 
ATOM   2245  C CG    . LYS A 1 476 ? 93.940  177.066 183.057 1.00 48.56  ? 447 LYS A CG    1 
ATOM   2246  C CD    . LYS A 1 476 ? 93.953  175.554 182.757 1.00 48.56  ? 447 LYS A CD    1 
ATOM   2247  C CE    . LYS A 1 476 ? 92.560  175.019 182.450 1.00 48.56  ? 447 LYS A CE    1 
ATOM   2248  N NZ    . LYS A 1 476 ? 92.540  173.534 182.372 1.00 48.56  ? 447 LYS A NZ    1 
ATOM   2249  N N     . LEU A 1 477 ? 94.180  179.660 179.155 1.00 47.46  ? 448 LEU A N     1 
ATOM   2250  C CA    . LEU A 1 477 ? 93.737  180.586 178.114 1.00 47.46  ? 448 LEU A CA    1 
ATOM   2251  C C     . LEU A 1 477 ? 93.766  179.925 176.740 1.00 47.46  ? 448 LEU A C     1 
ATOM   2252  O O     . LEU A 1 477 ? 92.838  180.095 175.940 1.00 47.46  ? 448 LEU A O     1 
ATOM   2253  C CB    . LEU A 1 477 ? 94.600  181.850 178.106 1.00 47.46  ? 448 LEU A CB    1 
ATOM   2254  C CG    . LEU A 1 477 ? 94.051  183.053 178.876 1.00 47.46  ? 448 LEU A CG    1 
ATOM   2255  C CD1   . LEU A 1 477 ? 94.182  182.841 180.373 1.00 47.46  ? 448 LEU A CD1   1 
ATOM   2256  C CD2   . LEU A 1 477 ? 94.767  184.324 178.451 1.00 47.46  ? 448 LEU A CD2   1 
ATOM   2257  N N     . LEU A 1 478 ? 94.823  179.167 176.450 1.00 48.30  ? 449 LEU A N     1 
ATOM   2258  C CA    . LEU A 1 478 ? 94.943  178.537 175.136 1.00 48.30  ? 449 LEU A CA    1 
ATOM   2259  C C     . LEU A 1 478 ? 93.922  177.425 174.939 1.00 48.30  ? 449 LEU A C     1 
ATOM   2260  O O     . LEU A 1 478 ? 93.480  177.193 173.808 1.00 48.30  ? 449 LEU A O     1 
ATOM   2261  C CB    . LEU A 1 478 ? 96.356  177.983 174.932 1.00 48.30  ? 449 LEU A CB    1 
ATOM   2262  C CG    . LEU A 1 478 ? 97.356  178.870 174.186 1.00 48.30  ? 449 LEU A CG    1 
ATOM   2263  C CD1   . LEU A 1 478 ? 97.098  178.814 172.692 1.00 48.30  ? 449 LEU A CD1   1 
ATOM   2264  C CD2   . LEU A 1 478 ? 97.321  180.314 174.682 1.00 48.30  ? 449 LEU A CD2   1 
ATOM   2265  N N     . HIS A 1 479 ? 93.557  176.713 176.008 1.00 52.29  ? 450 HIS A N     1 
ATOM   2266  C CA    . HIS A 1 479 ? 92.559  175.656 175.883 1.00 52.29  ? 450 HIS A CA    1 
ATOM   2267  C C     . HIS A 1 479 ? 91.206  176.232 175.492 1.00 52.29  ? 450 HIS A C     1 
ATOM   2268  O O     . HIS A 1 479 ? 90.493  175.656 174.661 1.00 52.29  ? 450 HIS A O     1 
ATOM   2269  C CB    . HIS A 1 479 ? 92.455  174.875 177.192 1.00 52.29  ? 450 HIS A CB    1 
ATOM   2270  C CG    . HIS A 1 479 ? 91.669  173.607 177.073 1.00 52.29  ? 450 HIS A CG    1 
ATOM   2271  N ND1   . HIS A 1 479 ? 92.073  172.554 176.282 1.00 52.29  ? 450 HIS A ND1   1 
ATOM   2272  C CD2   . HIS A 1 479 ? 90.503  173.223 177.644 1.00 52.29  ? 450 HIS A CD2   1 
ATOM   2273  C CE1   . HIS A 1 479 ? 91.190  171.576 176.370 1.00 52.29  ? 450 HIS A CE1   1 
ATOM   2274  N NE2   . HIS A 1 479 ? 90.228  171.956 177.190 1.00 52.29  ? 450 HIS A NE2   1 
ATOM   2275  N N     . GLU A 1 480 ? 90.838  177.368 176.074 1.00 55.38  ? 451 GLU A N     1 
ATOM   2276  C CA    . GLU A 1 480 ? 89.667  178.093 175.615 1.00 55.38  ? 451 GLU A CA    1 
ATOM   2277  C C     . GLU A 1 480 ? 89.911  178.639 174.214 1.00 55.38  ? 451 GLU A C     1 
ATOM   2278  O O     . GLU A 1 480 ? 91.046  178.946 173.839 1.00 55.38  ? 451 GLU A O     1 
ATOM   2279  C CB    . GLU A 1 480 ? 89.335  179.235 176.573 1.00 55.38  ? 451 GLU A CB    1 
ATOM   2280  C CG    . GLU A 1 480 ? 88.999  178.775 177.980 1.00 55.38  ? 451 GLU A CG    1 
ATOM   2281  C CD    . GLU A 1 480 ? 88.336  179.860 178.801 1.00 55.38  ? 451 GLU A CD    1 
ATOM   2282  O OE1   . GLU A 1 480 ? 88.887  180.979 178.865 1.00 55.38  ? 451 GLU A OE1   1 
ATOM   2283  O OE2   . GLU A 1 480 ? 87.263  179.594 179.382 1.00 55.38  ? 451 GLU A OE2   1 
ATOM   2284  N N     . GLN A 1 481 ? 88.816  178.791 173.464 1.00 57.46  ? 452 GLN A N     1 
ATOM   2285  C CA    . GLN A 1 481 ? 88.780  179.150 172.032 1.00 57.46  ? 452 GLN A CA    1 
ATOM   2286  C C     . GLN A 1 481 ? 89.864  178.460 171.189 1.00 57.46  ? 452 GLN A C     1 
ATOM   2287  O O     . GLN A 1 481 ? 90.307  177.357 171.510 1.00 57.46  ? 452 GLN A O     1 
ATOM   2288  C CB    . GLN A 1 481 ? 88.855  180.684 171.831 1.00 57.46  ? 452 GLN A CB    1 
ATOM   2289  C CG    . GLN A 1 481 ? 90.088  181.441 172.369 1.00 57.46  ? 452 GLN A CG    1 
ATOM   2290  C CD    . GLN A 1 481 ? 89.982  181.877 173.827 1.00 57.46  ? 452 GLN A CD    1 
ATOM   2291  O OE1   . GLN A 1 481 ? 88.995  181.600 174.509 1.00 57.46  ? 452 GLN A OE1   1 
ATOM   2292  N NE2   . GLN A 1 481 ? 91.010  182.564 174.308 1.00 57.46  ? 452 GLN A NE2   1 
ATOM   2293  N N     . GLN B 2 63  ? 111.835 132.597 206.917 1.00 45.34  ? 45  GLN D N     1 
ATOM   2294  C CA    . GLN B 2 63  ? 111.956 131.768 205.685 1.00 45.34  ? 45  GLN D CA    1 
ATOM   2295  C C     . GLN B 2 63  ? 112.396 130.354 206.042 1.00 45.34  ? 45  GLN D C     1 
ATOM   2296  O O     . GLN B 2 63  ? 113.502 129.937 205.704 1.00 45.34  ? 45  GLN D O     1 
ATOM   2297  C CB    . GLN B 2 63  ? 112.952 132.401 204.703 1.00 45.34  ? 45  GLN D CB    1 
ATOM   2298  C CG    . GLN B 2 63  ? 112.670 133.857 204.332 1.00 45.34  ? 45  GLN D CG    1 
ATOM   2299  C CD    . GLN B 2 63  ? 111.257 134.088 203.840 1.00 45.34  ? 45  GLN D CD    1 
ATOM   2300  O OE1   . GLN B 2 63  ? 110.691 133.258 203.131 1.00 45.34  ? 45  GLN D OE1   1 
ATOM   2301  N NE2   . GLN B 2 63  ? 110.672 135.212 204.229 1.00 45.34  ? 45  GLN D NE2   1 
ATOM   2302  N N     . VAL B 2 64  ? 111.516 129.628 206.725 1.00 42.64  ? 46  VAL D N     1 
ATOM   2303  C CA    . VAL B 2 64  ? 111.764 128.245 207.114 1.00 42.64  ? 46  VAL D CA    1 
ATOM   2304  C C     . VAL B 2 64  ? 111.198 127.271 206.091 1.00 42.64  ? 46  VAL D C     1 
ATOM   2305  O O     . VAL B 2 64  ? 111.863 126.305 205.717 1.00 42.64  ? 46  VAL D O     1 
ATOM   2306  C CB    . VAL B 2 64  ? 111.181 127.979 208.519 1.00 42.64  ? 46  VAL D CB    1 
ATOM   2307  C CG1   . VAL B 2 64  ? 111.374 126.503 208.910 1.00 42.64  ? 46  VAL D CG1   1 
ATOM   2308  C CG2   . VAL B 2 64  ? 111.812 128.930 209.546 1.00 42.64  ? 46  VAL D CG2   1 
ATOM   2309  N N     . LYS B 2 65  ? 109.967 127.510 205.633 1.00 41.30  ? 47  LYS D N     1 
ATOM   2310  C CA    . LYS B 2 65  ? 109.361 126.627 204.643 1.00 41.30  ? 47  LYS D CA    1 
ATOM   2311  C C     . LYS B 2 65  ? 110.071 126.732 203.299 1.00 41.30  ? 47  LYS D C     1 
ATOM   2312  O O     . LYS B 2 65  ? 110.289 125.719 202.625 1.00 41.30  ? 47  LYS D O     1 
ATOM   2313  C CB    . LYS B 2 65  ? 107.877 126.956 204.497 1.00 41.30  ? 47  LYS D CB    1 
ATOM   2314  C CG    . LYS B 2 65  ? 107.066 125.876 203.789 1.00 41.30  ? 47  LYS D CG    1 
ATOM   2315  C CD    . LYS B 2 65  ? 105.553 126.064 203.952 1.00 41.30  ? 47  LYS D CD    1 
ATOM   2316  C CE    . LYS B 2 65  ? 104.875 124.805 204.477 1.00 41.30  ? 47  LYS D CE    1 
ATOM   2317  N NZ    . LYS B 2 65  ? 103.441 125.042 204.801 1.00 41.30  ? 47  LYS D NZ    1 
ATOM   2318  N N     . ALA B 2 66  ? 110.436 127.951 202.892 1.00 41.91  ? 48  ALA D N     1 
ATOM   2319  C CA    . ALA B 2 66  ? 111.162 128.126 201.638 1.00 41.91  ? 48  ALA D CA    1 
ATOM   2320  C C     . ALA B 2 66  ? 112.544 127.486 201.703 1.00 41.91  ? 48  ALA D C     1 
ATOM   2321  O O     . ALA B 2 66  ? 112.993 126.865 200.733 1.00 41.91  ? 48  ALA D O     1 
ATOM   2322  C CB    . ALA B 2 66  ? 111.276 129.611 201.302 1.00 41.91  ? 48  ALA D CB    1 
ATOM   2323  N N     . ARG B 2 67  ? 113.236 127.633 202.836 1.00 43.47  ? 49  ARG D N     1 
ATOM   2324  C CA    . ARG B 2 67  ? 114.533 126.982 202.997 1.00 43.47  ? 49  ARG D CA    1 
ATOM   2325  C C     . ARG B 2 67  ? 114.386 125.467 202.996 1.00 43.47  ? 49  ARG D C     1 
ATOM   2326  O O     . ARG B 2 67  ? 115.247 124.751 202.472 1.00 43.47  ? 49  ARG D O     1 
ATOM   2327  C CB    . ARG B 2 67  ? 115.205 127.448 204.289 1.00 43.47  ? 49  ARG D CB    1 
ATOM   2328  C CG    . ARG B 2 67  ? 115.940 128.771 204.161 1.00 43.47  ? 49  ARG D CG    1 
ATOM   2329  C CD    . ARG B 2 67  ? 116.690 129.125 205.433 1.00 43.47  ? 49  ARG D CD    1 
ATOM   2330  N NE    . ARG B 2 67  ? 117.856 128.265 205.634 1.00 43.47  ? 49  ARG D NE    1 
ATOM   2331  C CZ    . ARG B 2 67  ? 117.962 127.252 206.491 1.00 43.47  ? 49  ARG D CZ    1 
ATOM   2332  N NH1   . ARG B 2 67  ? 116.943 126.842 207.236 1.00 43.47  ? 49  ARG D NH1   1 
ATOM   2333  N NH2   . ARG B 2 67  ? 119.125 126.615 206.593 1.00 43.47  ? 49  ARG D NH2   1 
ATOM   2334  N N     . LYS B 2 68  ? 113.299 124.961 203.582 1.00 42.62  ? 50  LYS D N     1 
ATOM   2335  C CA    . LYS B 2 68  ? 113.032 123.527 203.554 1.00 42.62  ? 50  LYS D CA    1 
ATOM   2336  C C     . LYS B 2 68  ? 112.814 123.038 202.126 1.00 42.62  ? 50  LYS D C     1 
ATOM   2337  O O     . LYS B 2 68  ? 113.338 121.989 201.731 1.00 42.62  ? 50  LYS D O     1 
ATOM   2338  C CB    . LYS B 2 68  ? 111.822 123.229 204.447 1.00 42.62  ? 50  LYS D CB    1 
ATOM   2339  C CG    . LYS B 2 68  ? 111.175 121.857 204.303 1.00 42.62  ? 50  LYS D CG    1 
ATOM   2340  C CD    . LYS B 2 68  ? 110.128 121.663 205.386 1.00 42.62  ? 50  LYS D CD    1 
ATOM   2341  C CE    . LYS B 2 68  ? 109.474 120.302 205.298 1.00 42.62  ? 50  LYS D CE    1 
ATOM   2342  N NZ    . LYS B 2 68  ? 110.425 119.195 205.589 1.00 42.62  ? 50  LYS D NZ    1 
ATOM   2343  N N     . ALA B 2 69  ? 112.053 123.795 201.331 1.00 41.38  ? 51  ALA D N     1 
ATOM   2344  C CA    . ALA B 2 69  ? 111.832 123.420 199.937 1.00 41.38  ? 51  ALA D CA    1 
ATOM   2345  C C     . ALA B 2 69  ? 113.127 123.475 199.136 1.00 41.38  ? 51  ALA D C     1 
ATOM   2346  O O     . ALA B 2 69  ? 113.373 122.620 198.273 1.00 41.38  ? 51  ALA D O     1 
ATOM   2347  C CB    . ALA B 2 69  ? 110.778 124.335 199.319 1.00 41.38  ? 51  ALA D CB    1 
ATOM   2348  N N     . ALA B 2 70  ? 113.966 124.478 199.405 1.00 42.39  ? 52  ALA D N     1 
ATOM   2349  C CA    . ALA B 2 70  ? 115.265 124.555 198.747 1.00 42.39  ? 52  ALA D CA    1 
ATOM   2350  C C     . ALA B 2 70  ? 116.142 123.367 199.124 1.00 42.39  ? 52  ALA D C     1 
ATOM   2351  O O     . ALA B 2 70  ? 116.867 122.833 198.280 1.00 42.39  ? 52  ALA D O     1 
ATOM   2352  C CB    . ALA B 2 70  ? 115.957 125.868 199.104 1.00 42.39  ? 52  ALA D CB    1 
ATOM   2353  N N     . GLY B 2 71  ? 116.088 122.938 200.386 1.00 44.29  ? 53  GLY D N     1 
ATOM   2354  C CA    . GLY B 2 71  ? 116.831 121.753 200.786 1.00 44.29  ? 53  GLY D CA    1 
ATOM   2355  C C     . GLY B 2 71  ? 116.324 120.492 200.112 1.00 44.29  ? 53  GLY D C     1 
ATOM   2356  O O     . GLY B 2 71  ? 117.107 119.594 199.780 1.00 44.29  ? 53  GLY D O     1 
ATOM   2357  N N     . VAL B 2 72  ? 115.009 120.400 199.910 1.00 44.23  ? 54  VAL D N     1 
ATOM   2358  C CA    . VAL B 2 72  ? 114.457 119.258 199.186 1.00 44.23  ? 54  VAL D CA    1 
ATOM   2359  C C     . VAL B 2 72  ? 114.946 119.261 197.740 1.00 44.23  ? 54  VAL D C     1 
ATOM   2360  O O     . VAL B 2 72  ? 115.298 118.211 197.192 1.00 44.23  ? 54  VAL D O     1 
ATOM   2361  C CB    . VAL B 2 72  ? 112.918 119.250 199.277 1.00 44.23  ? 54  VAL D CB    1 
ATOM   2362  C CG1   . VAL B 2 72  ? 112.311 118.227 198.310 1.00 44.23  ? 54  VAL D CG1   1 
ATOM   2363  C CG2   . VAL B 2 72  ? 112.476 118.925 200.699 1.00 44.23  ? 54  VAL D CG2   1 
ATOM   2364  N N     . ILE B 2 73  ? 114.986 120.435 197.102 1.00 44.88  ? 55  ILE D N     1 
ATOM   2365  C CA    . ILE B 2 73  ? 115.517 120.497 195.738 1.00 44.88  ? 55  ILE D CA    1 
ATOM   2366  C C     . ILE B 2 73  ? 117.012 120.185 195.728 1.00 44.88  ? 55  ILE D C     1 
ATOM   2367  O O     . ILE B 2 73  ? 117.524 119.632 194.751 1.00 44.88  ? 55  ILE D O     1 
ATOM   2368  C CB    . ILE B 2 73  ? 115.198 121.860 195.081 1.00 44.88  ? 55  ILE D CB    1 
ATOM   2369  C CG1   . ILE B 2 73  ? 113.703 121.896 194.727 1.00 44.88  ? 55  ILE D CG1   1 
ATOM   2370  C CG2   . ILE B 2 73  ? 116.114 122.121 193.825 1.00 44.88  ? 55  ILE D CG2   1 
ATOM   2371  C CD1   . ILE B 2 73  ? 113.181 123.205 194.165 1.00 44.88  ? 55  ILE D CD1   1 
ATOM   2372  N N     . LEU B 2 74  ? 117.741 120.557 196.780 1.00 48.83  ? 56  LEU D N     1 
ATOM   2373  C CA    . LEU B 2 74  ? 119.157 120.207 196.864 1.00 48.83  ? 56  LEU D CA    1 
ATOM   2374  C C     . LEU B 2 74  ? 119.351 118.698 196.915 1.00 48.83  ? 56  LEU D C     1 
ATOM   2375  O O     . LEU B 2 74  ? 120.205 118.142 196.210 1.00 48.83  ? 56  LEU D O     1 
ATOM   2376  C CB    . LEU B 2 74  ? 119.777 120.854 198.101 1.00 48.83  ? 56  LEU D CB    1 
ATOM   2377  C CG    . LEU B 2 74  ? 120.185 122.325 198.148 1.00 48.83  ? 56  LEU D CG    1 
ATOM   2378  C CD1   . LEU B 2 74  ? 121.021 122.530 199.376 1.00 48.83  ? 56  LEU D CD1   1 
ATOM   2379  C CD2   . LEU B 2 74  ? 120.994 122.739 196.935 1.00 48.83  ? 56  LEU D CD2   1 
ATOM   2380  N N     . GLN B 2 75  ? 118.568 118.019 197.754 1.00 49.47  ? 57  GLN D N     1 
ATOM   2381  C CA    . GLN B 2 75  ? 118.633 116.563 197.799 1.00 49.47  ? 57  GLN D CA    1 
ATOM   2382  C C     . GLN B 2 75  ? 118.185 115.952 196.477 1.00 49.47  ? 57  GLN D C     1 
ATOM   2383  O O     . GLN B 2 75  ? 118.672 114.885 196.089 1.00 49.47  ? 57  GLN D O     1 
ATOM   2384  C CB    . GLN B 2 75  ? 117.784 116.038 198.961 1.00 49.47  ? 57  GLN D CB    1 
ATOM   2385  C CG    . GLN B 2 75  ? 117.874 114.530 199.236 1.00 49.47  ? 57  GLN D CG    1 
ATOM   2386  C CD    . GLN B 2 75  ? 119.276 114.062 199.590 1.00 49.47  ? 57  GLN D CD    1 
ATOM   2387  O OE1   . GLN B 2 75  ? 120.145 113.961 198.724 1.00 49.47  ? 57  GLN D OE1   1 
ATOM   2388  N NE2   . GLN B 2 75  ? 119.503 113.777 200.867 1.00 49.47  ? 57  GLN D NE2   1 
ATOM   2389  N N     . MET B 2 76  ? 117.258 116.612 195.779 1.00 47.53  ? 58  MET D N     1 
ATOM   2390  C CA    . MET B 2 76  ? 116.886 116.185 194.433 1.00 47.53  ? 58  MET D CA    1 
ATOM   2391  C C     . MET B 2 76  ? 118.066 116.290 193.473 1.00 47.53  ? 58  MET D C     1 
ATOM   2392  O O     . MET B 2 76  ? 118.316 115.378 192.678 1.00 47.53  ? 58  MET D O     1 
ATOM   2393  C CB    . MET B 2 76  ? 115.722 117.040 193.933 1.00 47.53  ? 58  MET D CB    1 
ATOM   2394  C CG    . MET B 2 76  ? 114.863 116.395 192.873 1.00 47.53  ? 58  MET D CG    1 
ATOM   2395  S SD    . MET B 2 76  ? 113.547 117.498 192.334 1.00 47.53  ? 58  MET D SD    1 
ATOM   2396  C CE    . MET B 2 76  ? 112.393 117.336 193.689 1.00 47.53  ? 58  MET D CE    1 
ATOM   2397  N N     . ILE B 2 77  ? 118.796 117.405 193.533 1.00 46.25  ? 59  ILE D N     1 
ATOM   2398  C CA    . ILE B 2 77  ? 119.882 117.654 192.589 1.00 46.25  ? 59  ILE D CA    1 
ATOM   2399  C C     . ILE B 2 77  ? 121.038 116.698 192.847 1.00 46.25  ? 59  ILE D C     1 
ATOM   2400  O O     . ILE B 2 77  ? 121.722 116.269 191.909 1.00 46.25  ? 59  ILE D O     1 
ATOM   2401  C CB    . ILE B 2 77  ? 120.333 119.128 192.664 1.00 46.25  ? 59  ILE D CB    1 
ATOM   2402  C CG1   . ILE B 2 77  ? 119.252 120.067 192.114 1.00 46.25  ? 59  ILE D CG1   1 
ATOM   2403  C CG2   . ILE B 2 77  ? 121.632 119.354 191.880 1.00 46.25  ? 59  ILE D CG2   1 
ATOM   2404  C CD1   . ILE B 2 77  ? 119.297 121.459 192.710 1.00 46.25  ? 59  ILE D CD1   1 
ATOM   2405  N N     . ARG B 2 78  ? 121.298 116.377 194.118 1.00 50.69  ? 60  ARG D N     1 
ATOM   2406  C CA    . ARG B 2 78  ? 122.369 115.435 194.436 1.00 50.69  ? 60  ARG D CA    1 
ATOM   2407  C C     . ARG B 2 78  ? 122.074 114.051 193.869 1.00 50.69  ? 60  ARG D C     1 
ATOM   2408  O O     . ARG B 2 78  ? 122.982 113.362 193.390 1.00 50.69  ? 60  ARG D O     1 
ATOM   2409  C CB    . ARG B 2 78  ? 122.578 115.357 195.947 1.00 50.69  ? 60  ARG D CB    1 
ATOM   2410  C CG    . ARG B 2 78  ? 123.279 116.574 196.538 1.00 50.69  ? 60  ARG D CG    1 
ATOM   2411  C CD    . ARG B 2 78  ? 123.663 116.365 198.002 1.00 50.69  ? 60  ARG D CD    1 
ATOM   2412  N NE    . ARG B 2 78  ? 122.975 117.283 198.904 1.00 50.69  ? 60  ARG D NE    1 
ATOM   2413  C CZ    . ARG B 2 78  ? 123.188 118.592 198.984 1.00 50.69  ? 60  ARG D CZ    1 
ATOM   2414  N NH1   . ARG B 2 78  ? 124.062 119.213 198.202 1.00 50.69  ? 60  ARG D NH1   1 
ATOM   2415  N NH2   . ARG B 2 78  ? 122.505 119.304 199.877 1.00 50.69  ? 60  ARG D NH2   1 
ATOM   2416  N N     . GLU B 2 79  ? 120.812 113.632 193.909 1.00 50.92  ? 61  GLU D N     1 
ATOM   2417  C CA    . GLU B 2 79  ? 120.397 112.360 193.330 1.00 50.92  ? 61  GLU D CA    1 
ATOM   2418  C C     . GLU B 2 79  ? 120.224 112.414 191.813 1.00 50.92  ? 61  GLU D C     1 
ATOM   2419  O O     . GLU B 2 79  ? 119.922 111.378 191.212 1.00 50.92  ? 61  GLU D O     1 
ATOM   2420  C CB    . GLU B 2 79  ? 119.087 111.894 193.972 1.00 50.92  ? 61  GLU D CB    1 
ATOM   2421  C CG    . GLU B 2 79  ? 119.147 111.724 195.495 1.00 50.92  ? 61  GLU D CG    1 
ATOM   2422  C CD    . GLU B 2 79  ? 118.811 110.316 195.961 1.00 50.92  ? 61  GLU D CD    1 
ATOM   2423  O OE1   . GLU B 2 79  ? 119.308 109.341 195.358 1.00 50.92  ? 61  GLU D OE1   1 
ATOM   2424  O OE2   . GLU B 2 79  ? 118.046 110.186 196.940 1.00 50.92  ? 61  GLU D OE2   1 
ATOM   2425  N N     . GLY B 2 80  ? 120.395 113.575 191.178 1.00 50.28  ? 62  GLY D N     1 
ATOM   2426  C CA    . GLY B 2 80  ? 120.225 113.680 189.743 1.00 50.28  ? 62  GLY D CA    1 
ATOM   2427  C C     . GLY B 2 80  ? 118.792 113.678 189.263 1.00 50.28  ? 62  GLY D C     1 
ATOM   2428  O O     . GLY B 2 80  ? 118.562 113.510 188.060 1.00 50.28  ? 62  GLY D O     1 
ATOM   2429  N N     . LYS B 2 81  ? 117.820 113.868 190.157 1.00 49.69  ? 63  LYS D N     1 
ATOM   2430  C CA    . LYS B 2 81  ? 116.408 113.792 189.804 1.00 49.69  ? 63  LYS D CA    1 
ATOM   2431  C C     . LYS B 2 81  ? 115.843 115.098 189.255 1.00 49.69  ? 63  LYS D C     1 
ATOM   2432  O O     . LYS B 2 81  ? 114.678 115.111 188.842 1.00 49.69  ? 63  LYS D O     1 
ATOM   2433  C CB    . LYS B 2 81  ? 115.594 113.371 191.031 1.00 49.69  ? 63  LYS D CB    1 
ATOM   2434  C CG    . LYS B 2 81  ? 115.757 111.914 191.434 1.00 49.69  ? 63  LYS D CG    1 
ATOM   2435  C CD    . LYS B 2 81  ? 115.006 110.967 190.500 1.00 49.69  ? 63  LYS D CD    1 
ATOM   2436  C CE    . LYS B 2 81  ? 114.955 109.543 191.040 1.00 49.69  ? 63  LYS D CE    1 
ATOM   2437  N NZ    . LYS B 2 81  ? 114.213 109.425 192.329 1.00 49.69  ? 63  LYS D NZ    1 
ATOM   2438  N N     . ILE B 2 82  ? 116.613 116.191 189.246 1.00 45.51  ? 64  ILE D N     1 
ATOM   2439  C CA    . ILE B 2 82  ? 116.076 117.462 188.767 1.00 45.51  ? 64  ILE D CA    1 
ATOM   2440  C C     . ILE B 2 82  ? 115.806 117.393 187.265 1.00 45.51  ? 64  ILE D C     1 
ATOM   2441  O O     . ILE B 2 82  ? 114.809 117.943 186.782 1.00 45.51  ? 64  ILE D O     1 
ATOM   2442  C CB    . ILE B 2 82  ? 117.019 118.624 189.154 1.00 45.51  ? 64  ILE D CB    1 
ATOM   2443  C CG1   . ILE B 2 82  ? 116.321 119.986 189.032 1.00 45.51  ? 64  ILE D CG1   1 
ATOM   2444  C CG2   . ILE B 2 82  ? 118.301 118.625 188.327 1.00 45.51  ? 64  ILE D CG2   1 
ATOM   2445  C CD1   . ILE B 2 82  ? 115.358 120.295 190.163 1.00 45.51  ? 64  ILE D CD1   1 
ATOM   2446  N N     . ALA B 2 83  ? 116.661 116.690 186.519 1.00 46.08  ? 65  ALA D N     1 
ATOM   2447  C CA    . ALA B 2 83  ? 116.500 116.431 185.077 1.00 46.08  ? 65  ALA D CA    1 
ATOM   2448  C C     . ALA B 2 83  ? 116.464 117.775 184.346 1.00 46.08  ? 65  ALA D C     1 
ATOM   2449  O O     . ALA B 2 83  ? 117.349 118.610 184.591 1.00 46.08  ? 65  ALA D O     1 
ATOM   2450  C CB    . ALA B 2 83  ? 115.287 115.524 184.893 1.00 46.08  ? 65  ALA D CB    1 
ATOM   2451  N N     . GLY B 2 84  ? 115.488 118.034 183.468 1.00 41.74  ? 66  GLY D N     1 
ATOM   2452  C CA    . GLY B 2 84  ? 115.379 119.299 182.772 1.00 41.74  ? 66  GLY D CA    1 
ATOM   2453  C C     . GLY B 2 84  ? 114.649 120.400 183.509 1.00 41.74  ? 66  GLY D C     1 
ATOM   2454  O O     . GLY B 2 84  ? 114.489 121.489 182.952 1.00 41.74  ? 66  GLY D O     1 
ATOM   2455  N N     . ARG B 2 85  ? 114.201 120.163 184.740 1.00 43.32  ? 67  ARG D N     1 
ATOM   2456  C CA    . ARG B 2 85  ? 113.423 121.152 185.467 1.00 43.32  ? 67  ARG D CA    1 
ATOM   2457  C C     . ARG B 2 85  ? 114.334 122.242 186.032 1.00 43.32  ? 67  ARG D C     1 
ATOM   2458  O O     . ARG B 2 85  ? 115.563 122.131 186.025 1.00 43.32  ? 67  ARG D O     1 
ATOM   2459  C CB    . ARG B 2 85  ? 112.624 120.476 186.582 1.00 43.32  ? 67  ARG D CB    1 
ATOM   2460  C CG    . ARG B 2 85  ? 111.502 119.588 186.065 1.00 43.32  ? 67  ARG D CG    1 
ATOM   2461  C CD    . ARG B 2 85  ? 110.836 118.795 187.171 1.00 43.32  ? 67  ARG D CD    1 
ATOM   2462  N NE    . ARG B 2 85  ? 111.679 117.708 187.657 1.00 43.32  ? 67  ARG D NE    1 
ATOM   2463  C CZ    . ARG B 2 85  ? 111.324 116.805 188.564 1.00 43.32  ? 67  ARG D CZ    1 
ATOM   2464  N NH1   . ARG B 2 85  ? 110.126 116.811 189.133 1.00 43.32  ? 67  ARG D NH1   1 
ATOM   2465  N NH2   . ARG B 2 85  ? 112.195 115.862 188.911 1.00 43.32  ? 67  ARG D NH2   1 
ATOM   2466  N N     . ALA B 2 86  ? 113.707 123.313 186.514 1.00 41.92  ? 68  ALA D N     1 
ATOM   2467  C CA    . ALA B 2 86  ? 114.396 124.460 187.096 1.00 41.92  ? 68  ALA D CA    1 
ATOM   2468  C C     . ALA B 2 86  ? 113.588 124.912 188.309 1.00 41.92  ? 68  ALA D C     1 
ATOM   2469  O O     . ALA B 2 86  ? 112.607 124.265 188.686 1.00 41.92  ? 68  ALA D O     1 
ATOM   2470  C CB    . ALA B 2 86  ? 114.578 125.558 186.040 1.00 41.92  ? 68  ALA D CB    1 
ATOM   2471  N N     . ILE B 2 87  ? 114.002 126.027 188.925 1.00 42.08  ? 69  ILE D N     1 
ATOM   2472  C CA    . ILE B 2 87  ? 113.393 126.548 190.145 1.00 42.08  ? 69  ILE D CA    1 
ATOM   2473  C C     . ILE B 2 87  ? 112.950 127.979 189.888 1.00 42.08  ? 69  ILE D C     1 
ATOM   2474  O O     . ILE B 2 87  ? 113.580 128.715 189.123 1.00 42.08  ? 69  ILE D O     1 
ATOM   2475  C CB    . ILE B 2 87  ? 114.377 126.473 191.337 1.00 42.08  ? 69  ILE D CB    1 
ATOM   2476  C CG1   . ILE B 2 87  ? 114.845 125.026 191.526 1.00 42.08  ? 69  ILE D CG1   1 
ATOM   2477  C CG2   . ILE B 2 87  ? 113.741 127.020 192.645 1.00 42.08  ? 69  ILE D CG2   1 
ATOM   2478  C CD1   . ILE B 2 87  ? 116.222 124.752 190.968 1.00 42.08  ? 69  ILE D CD1   1 
ATOM   2479  N N     . LEU B 2 88  ? 111.840 128.359 190.523 1.00 43.35  ? 70  LEU D N     1 
ATOM   2480  C CA    . LEU B 2 88  ? 111.373 129.738 190.589 1.00 43.35  ? 70  LEU D CA    1 
ATOM   2481  C C     . LEU B 2 88  ? 111.168 130.117 192.044 1.00 43.35  ? 70  LEU D C     1 
ATOM   2482  O O     . LEU B 2 88  ? 110.574 129.348 192.807 1.00 43.35  ? 70  LEU D O     1 
ATOM   2483  C CB    . LEU B 2 88  ? 110.078 129.936 189.791 1.00 43.35  ? 70  LEU D CB    1 
ATOM   2484  C CG    . LEU B 2 88  ? 109.365 131.302 189.806 1.00 43.35  ? 70  LEU D CG    1 
ATOM   2485  C CD1   . LEU B 2 88  ? 110.194 132.400 189.171 1.00 43.35  ? 70  LEU D CD1   1 
ATOM   2486  C CD2   . LEU B 2 88  ? 108.025 131.202 189.099 1.00 43.35  ? 70  LEU D CD2   1 
ATOM   2487  N N     . ILE B 2 89  ? 111.665 131.297 192.417 1.00 44.57  ? 71  ILE D N     1 
ATOM   2488  C CA    . ILE B 2 89  ? 111.437 131.889 193.734 1.00 44.57  ? 71  ILE D CA    1 
ATOM   2489  C C     . ILE B 2 89  ? 110.417 133.003 193.533 1.00 44.57  ? 71  ILE D C     1 
ATOM   2490  O O     . ILE B 2 89  ? 110.719 134.023 192.900 1.00 44.57  ? 71  ILE D O     1 
ATOM   2491  C CB    . ILE B 2 89  ? 112.725 132.435 194.375 1.00 44.57  ? 71  ILE D CB    1 
ATOM   2492  C CG1   . ILE B 2 89  ? 113.908 131.445 194.314 1.00 44.57  ? 71  ILE D CG1   1 
ATOM   2493  C CG2   . ILE B 2 89  ? 112.461 132.828 195.836 1.00 44.57  ? 71  ILE D CG2   1 
ATOM   2494  C CD1   . ILE B 2 89  ? 113.789 130.234 195.213 1.00 44.57  ? 71  ILE D CD1   1 
ATOM   2495  N N     . ALA B 2 90  ? 109.219 132.823 194.095 1.00 43.73  ? 72  ALA D N     1 
ATOM   2496  C CA    . ALA B 2 90  ? 108.082 133.719 193.888 1.00 43.73  ? 72  ALA D CA    1 
ATOM   2497  C C     . ALA B 2 90  ? 107.660 134.307 195.227 1.00 43.73  ? 72  ALA D C     1 
ATOM   2498  O O     . ALA B 2 90  ? 107.125 133.594 196.081 1.00 43.73  ? 72  ALA D O     1 
ATOM   2499  C CB    . ALA B 2 90  ? 106.920 132.973 193.237 1.00 43.73  ? 72  ALA D CB    1 
ATOM   2500  N N     . GLY B 2 91  ? 107.868 135.605 195.398 1.00 46.83  ? 73  GLY D N     1 
ATOM   2501  C CA    . GLY B 2 91  ? 107.437 136.264 196.612 1.00 46.83  ? 73  GLY D CA    1 
ATOM   2502  C C     . GLY B 2 91  ? 107.628 137.758 196.507 1.00 46.83  ? 73  GLY D C     1 
ATOM   2503  O O     . GLY B 2 91  ? 108.033 138.277 195.467 1.00 46.83  ? 73  GLY D O     1 
ATOM   2504  N N     . GLN B 2 92  ? 107.352 138.448 197.611 1.00 48.61  ? 74  GLN D N     1 
ATOM   2505  C CA    . GLN B 2 92  ? 107.448 139.896 197.615 1.00 48.61  ? 74  GLN D CA    1 
ATOM   2506  C C     . GLN B 2 92  ? 108.915 140.322 197.505 1.00 48.61  ? 74  GLN D C     1 
ATOM   2507  O O     . GLN B 2 92  ? 109.813 139.524 197.782 1.00 48.61  ? 74  GLN D O     1 
ATOM   2508  C CB    . GLN B 2 92  ? 106.816 140.465 198.883 1.00 48.61  ? 74  GLN D CB    1 
ATOM   2509  C CG    . GLN B 2 92  ? 105.307 140.251 198.992 1.00 48.61  ? 74  GLN D CG    1 
ATOM   2510  C CD    . GLN B 2 92  ? 104.511 141.133 198.045 1.00 48.61  ? 74  GLN D CD    1 
ATOM   2511  O OE1   . GLN B 2 92  ? 104.536 140.942 196.831 1.00 48.61  ? 74  GLN D OE1   1 
ATOM   2512  N NE2   . GLN B 2 92  ? 103.799 142.108 198.600 1.00 48.61  ? 74  GLN D NE2   1 
ATOM   2513  N N     . PRO B 2 93  ? 109.191 141.562 197.077 1.00 49.44  ? 75  PRO D N     1 
ATOM   2514  C CA    . PRO B 2 93  ? 110.591 141.962 196.867 1.00 49.44  ? 75  PRO D CA    1 
ATOM   2515  C C     . PRO B 2 93  ? 111.394 142.008 198.158 1.00 49.44  ? 75  PRO D C     1 
ATOM   2516  O O     . PRO B 2 93  ? 110.882 142.339 199.230 1.00 49.44  ? 75  PRO D O     1 
ATOM   2517  C CB    . PRO B 2 93  ? 110.478 143.363 196.252 1.00 49.44  ? 75  PRO D CB    1 
ATOM   2518  C CG    . PRO B 2 93  ? 109.087 143.489 195.794 1.00 49.44  ? 75  PRO D CG    1 
ATOM   2519  C CD    . PRO B 2 93  ? 108.276 142.667 196.727 1.00 49.44  ? 75  PRO D CD    1 
ATOM   2520  N N     . GLY B 2 94  ? 112.677 141.679 198.033 1.00 51.27  ? 76  GLY D N     1 
ATOM   2521  C CA    . GLY B 2 94  ? 113.597 141.763 199.158 1.00 51.27  ? 76  GLY D CA    1 
ATOM   2522  C C     . GLY B 2 94  ? 113.262 140.837 200.306 1.00 51.27  ? 76  GLY D C     1 
ATOM   2523  O O     . GLY B 2 94  ? 113.346 141.247 201.471 1.00 51.27  ? 76  GLY D O     1 
ATOM   2524  N N     . THR B 2 95  ? 112.884 139.593 200.000 1.00 48.05  ? 77  THR D N     1 
ATOM   2525  C CA    . THR B 2 95  ? 112.486 138.580 200.976 1.00 48.05  ? 77  THR D CA    1 
ATOM   2526  C C     . THR B 2 95  ? 113.448 137.394 200.954 1.00 48.05  ? 77  THR D C     1 
ATOM   2527  O O     . THR B 2 95  ? 113.042 136.236 201.052 1.00 48.05  ? 77  THR D O     1 
ATOM   2528  C CB    . THR B 2 95  ? 111.049 138.126 200.708 1.00 48.05  ? 77  THR D CB    1 
ATOM   2529  O OG1   . THR B 2 95  ? 110.241 139.263 200.381 1.00 48.05  ? 77  THR D OG1   1 
ATOM   2530  C CG2   . THR B 2 95  ? 110.425 137.402 201.913 1.00 48.05  ? 77  THR D CG2   1 
ATOM   2531  N N     . GLY B 2 96  ? 114.742 137.673 200.816 1.00 48.06  ? 78  GLY D N     1 
ATOM   2532  C CA    . GLY B 2 96  ? 115.743 136.629 200.900 1.00 48.06  ? 78  GLY D CA    1 
ATOM   2533  C C     . GLY B 2 96  ? 115.878 135.760 199.671 1.00 48.06  ? 78  GLY D C     1 
ATOM   2534  O O     . GLY B 2 96  ? 116.265 134.595 199.790 1.00 48.06  ? 78  GLY D O     1 
ATOM   2535  N N     . LYS B 2 97  ? 115.570 136.292 198.487 1.00 46.80  ? 79  LYS D N     1 
ATOM   2536  C CA    . LYS B 2 97  ? 115.689 135.507 197.261 1.00 46.80  ? 79  LYS D CA    1 
ATOM   2537  C C     . LYS B 2 97  ? 117.145 135.173 196.962 1.00 46.80  ? 79  LYS D C     1 
ATOM   2538  O O     . LYS B 2 97  ? 117.514 133.999 196.819 1.00 46.80  ? 79  LYS D O     1 
ATOM   2539  C CB    . LYS B 2 97  ? 115.077 136.277 196.093 1.00 46.80  ? 79  LYS D CB    1 
ATOM   2540  C CG    . LYS B 2 97  ? 113.576 136.374 196.133 1.00 46.80  ? 79  LYS D CG    1 
ATOM   2541  C CD    . LYS B 2 97  ? 113.074 137.538 195.302 1.00 46.80  ? 79  LYS D CD    1 
ATOM   2542  C CE    . LYS B 2 97  ? 111.598 137.402 194.976 1.00 46.80  ? 79  LYS D CE    1 
ATOM   2543  N NZ    . LYS B 2 97  ? 110.717 137.331 196.173 1.00 46.80  ? 79  LYS D NZ    1 
ATOM   2544  N N     . THR B 2 98  ? 117.985 136.204 196.853 1.00 50.20  ? 80  THR D N     1 
ATOM   2545  C CA    . THR B 2 98  ? 119.392 135.987 196.541 1.00 50.20  ? 80  THR D CA    1 
ATOM   2546  C C     . THR B 2 98  ? 120.100 135.242 197.661 1.00 50.20  ? 80  THR D C     1 
ATOM   2547  O O     . THR B 2 98  ? 121.026 134.469 197.396 1.00 50.20  ? 80  THR D O     1 
ATOM   2548  C CB    . THR B 2 98  ? 120.078 137.325 196.271 1.00 50.20  ? 80  THR D CB    1 
ATOM   2549  O OG1   . THR B 2 98  ? 119.173 138.196 195.581 1.00 50.20  ? 80  THR D OG1   1 
ATOM   2550  C CG2   . THR B 2 98  ? 121.328 137.126 195.424 1.00 50.20  ? 80  THR D CG2   1 
ATOM   2551  N N     . ALA B 2 99  ? 119.673 135.449 198.910 1.00 51.24  ? 81  ALA D N     1 
ATOM   2552  C CA    . ALA B 2 99  ? 120.210 134.665 200.017 1.00 51.24  ? 81  ALA D CA    1 
ATOM   2553  C C     . ALA B 2 99  ? 119.880 133.188 199.853 1.00 51.24  ? 81  ALA D C     1 
ATOM   2554  O O     . ALA B 2 99  ? 120.738 132.327 200.080 1.00 51.24  ? 81  ALA D O     1 
ATOM   2555  C CB    . ALA B 2 99  ? 119.665 135.188 201.344 1.00 51.24  ? 81  ALA D CB    1 
ATOM   2556  N N     . ILE B 2 100 ? 118.644 132.881 199.443 1.00 47.71  ? 82  ILE D N     1 
ATOM   2557  C CA    . ILE B 2 100 ? 118.237 131.495 199.216 1.00 47.71  ? 82  ILE D CA    1 
ATOM   2558  C C     . ILE B 2 100 ? 119.072 130.879 198.100 1.00 47.71  ? 82  ILE D C     1 
ATOM   2559  O O     . ILE B 2 100 ? 119.564 129.751 198.220 1.00 47.71  ? 82  ILE D O     1 
ATOM   2560  C CB    . ILE B 2 100 ? 116.726 131.430 198.906 1.00 47.71  ? 82  ILE D CB    1 
ATOM   2561  C CG1   . ILE B 2 100 ? 115.915 131.597 200.197 1.00 47.71  ? 82  ILE D CG1   1 
ATOM   2562  C CG2   . ILE B 2 100 ? 116.316 130.133 198.161 1.00 47.71  ? 82  ILE D CG2   1 
ATOM   2563  C CD1   . ILE B 2 100 ? 115.748 130.338 201.022 1.00 47.71  ? 82  ILE D CD1   1 
ATOM   2564  N N     . ALA B 2 101 ? 119.250 131.616 197.002 1.00 50.22  ? 83  ALA D N     1 
ATOM   2565  C CA    . ALA B 2 101 ? 119.999 131.080 195.869 1.00 50.22  ? 83  ALA D CA    1 
ATOM   2566  C C     . ALA B 2 101 ? 121.470 130.872 196.212 1.00 50.22  ? 83  ALA D C     1 
ATOM   2567  O O     . ALA B 2 101 ? 122.059 129.844 195.852 1.00 50.22  ? 83  ALA D O     1 
ATOM   2568  C CB    . ALA B 2 101 ? 119.862 132.013 194.674 1.00 50.22  ? 83  ALA D CB    1 
ATOM   2569  N N     . MET B 2 102 ? 122.084 131.835 196.902 1.00 56.77  ? 84  MET D N     1 
ATOM   2570  C CA    . MET B 2 102 ? 123.491 131.700 197.255 1.00 56.77  ? 84  MET D CA    1 
ATOM   2571  C C     . MET B 2 102 ? 123.694 130.591 198.277 1.00 56.77  ? 84  MET D C     1 
ATOM   2572  O O     . MET B 2 102 ? 124.687 129.859 198.210 1.00 56.77  ? 84  MET D O     1 
ATOM   2573  C CB    . MET B 2 102 ? 124.026 133.031 197.782 1.00 56.77  ? 84  MET D CB    1 
ATOM   2574  C CG    . MET B 2 102 ? 124.331 134.054 196.681 1.00 56.77  ? 84  MET D CG    1 
ATOM   2575  S SD    . MET B 2 102 ? 125.255 135.545 197.142 1.00 56.77  ? 84  MET D SD    1 
ATOM   2576  C CE    . MET B 2 102 ? 125.242 135.531 198.935 1.00 56.77  ? 84  MET D CE    1 
ATOM   2577  N N     . GLY B 2 103 ? 122.763 130.441 199.222 1.00 57.86  ? 85  GLY D N     1 
ATOM   2578  C CA    . GLY B 2 103 ? 122.839 129.322 200.144 1.00 57.86  ? 85  GLY D CA    1 
ATOM   2579  C C     . GLY B 2 103 ? 122.676 127.989 199.442 1.00 57.86  ? 85  GLY D C     1 
ATOM   2580  O O     . GLY B 2 103 ? 123.328 127.008 199.799 1.00 57.86  ? 85  GLY D O     1 
ATOM   2581  N N     . MET B 2 104 ? 121.811 127.942 198.427 1.00 50.73  ? 86  MET D N     1 
ATOM   2582  C CA    . MET B 2 104 ? 121.639 126.731 197.632 1.00 50.73  ? 86  MET D CA    1 
ATOM   2583  C C     . MET B 2 104 ? 122.934 126.369 196.913 1.00 50.73  ? 86  MET D C     1 
ATOM   2584  O O     . MET B 2 104 ? 123.384 125.216 196.949 1.00 50.73  ? 86  MET D O     1 
ATOM   2585  C CB    . MET B 2 104 ? 120.500 126.954 196.634 1.00 50.73  ? 86  MET D CB    1 
ATOM   2586  C CG    . MET B 2 104 ? 120.028 125.730 195.871 1.00 50.73  ? 86  MET D CG    1 
ATOM   2587  S SD    . MET B 2 104 ? 118.822 126.101 194.582 1.00 50.73  ? 86  MET D SD    1 
ATOM   2588  C CE    . MET B 2 104 ? 117.455 126.742 195.545 1.00 50.73  ? 86  MET D CE    1 
ATOM   2589  N N     . ALA B 2 105 ? 123.558 127.360 196.273 1.00 54.09  ? 87  ALA D N     1 
ATOM   2590  C CA    . ALA B 2 105 ? 124.801 127.117 195.545 1.00 54.09  ? 87  ALA D CA    1 
ATOM   2591  C C     . ALA B 2 105 ? 125.931 126.723 196.488 1.00 54.09  ? 87  ALA D C     1 
ATOM   2592  O O     . ALA B 2 105 ? 126.761 125.873 196.148 1.00 54.09  ? 87  ALA D O     1 
ATOM   2593  C CB    . ALA B 2 105 ? 125.182 128.356 194.738 1.00 54.09  ? 87  ALA D CB    1 
ATOM   2594  N N     . LYS B 2 106 ? 125.986 127.334 197.674 1.00 59.44  ? 88  LYS D N     1 
ATOM   2595  C CA    . LYS B 2 106 ? 127.003 126.962 198.652 1.00 59.44  ? 88  LYS D CA    1 
ATOM   2596  C C     . LYS B 2 106 ? 126.779 125.545 199.166 1.00 59.44  ? 88  LYS D C     1 
ATOM   2597  O O     . LYS B 2 106 ? 127.727 124.758 199.265 1.00 59.44  ? 88  LYS D O     1 
ATOM   2598  C CB    . LYS B 2 106 ? 126.995 127.963 199.809 1.00 59.44  ? 88  LYS D CB    1 
ATOM   2599  C CG    . LYS B 2 106 ? 128.012 127.680 200.914 1.00 59.44  ? 88  LYS D CG    1 
ATOM   2600  C CD    . LYS B 2 106 ? 127.362 127.059 202.153 1.00 59.44  ? 88  LYS D CD    1 
ATOM   2601  C CE    . LYS B 2 106 ? 126.624 128.087 203.004 1.00 59.44  ? 88  LYS D CE    1 
ATOM   2602  N NZ    . LYS B 2 106 ? 126.232 127.527 204.327 1.00 59.44  ? 88  LYS D NZ    1 
ATOM   2603  N N     . SER B 2 107 ? 125.534 125.203 199.498 1.00 55.81  ? 89  SER D N     1 
ATOM   2604  C CA    . SER B 2 107 ? 125.230 123.886 200.035 1.00 55.81  ? 89  SER D CA    1 
ATOM   2605  C C     . SER B 2 107 ? 125.407 122.785 199.001 1.00 55.81  ? 89  SER D C     1 
ATOM   2606  O O     . SER B 2 107 ? 125.626 121.629 199.380 1.00 55.81  ? 89  SER D O     1 
ATOM   2607  C CB    . SER B 2 107 ? 123.808 123.883 200.583 1.00 55.81  ? 89  SER D CB    1 
ATOM   2608  O OG    . SER B 2 107 ? 123.682 124.771 201.679 1.00 55.81  ? 89  SER D OG    1 
ATOM   2609  N N     . LEU B 2 108 ? 125.309 123.105 197.707 1.00 54.20  ? 90  LEU D N     1 
ATOM   2610  C CA    . LEU B 2 108 ? 125.806 122.173 196.699 1.00 54.20  ? 90  LEU D CA    1 
ATOM   2611  C C     . LEU B 2 108 ? 127.301 121.946 196.874 1.00 54.20  ? 90  LEU D C     1 
ATOM   2612  O O     . LEU B 2 108 ? 127.794 120.826 196.700 1.00 54.20  ? 90  LEU D O     1 
ATOM   2613  C CB    . LEU B 2 108 ? 125.510 122.694 195.290 1.00 54.20  ? 90  LEU D CB    1 
ATOM   2614  C CG    . LEU B 2 108 ? 124.073 122.640 194.763 1.00 54.20  ? 90  LEU D CG    1 
ATOM   2615  C CD1   . LEU B 2 108 ? 123.989 123.343 193.419 1.00 54.20  ? 90  LEU D CD1   1 
ATOM   2616  C CD2   . LEU B 2 108 ? 123.576 121.205 194.634 1.00 54.20  ? 90  LEU D CD2   1 
ATOM   2617  N N     . GLY B 2 109 ? 128.036 123.000 197.222 1.00 62.74  ? 91  GLY D N     1 
ATOM   2618  C CA    . GLY B 2 109 ? 129.457 122.909 197.485 1.00 62.74  ? 91  GLY D CA    1 
ATOM   2619  C C     . GLY B 2 109 ? 130.111 124.272 197.402 1.00 62.74  ? 91  GLY D C     1 
ATOM   2620  O O     . GLY B 2 109 ? 129.750 125.081 196.542 1.00 62.74  ? 91  GLY D O     1 
ATOM   2621  N N     . LEU B 2 110 ? 131.064 124.546 198.297 1.00 67.78  ? 92  LEU D N     1 
ATOM   2622  C CA    . LEU B 2 110 ? 131.754 125.833 198.267 1.00 67.78  ? 92  LEU D CA    1 
ATOM   2623  C C     . LEU B 2 110 ? 132.573 125.998 196.994 1.00 67.78  ? 92  LEU D C     1 
ATOM   2624  O O     . LEU B 2 110 ? 132.730 127.120 196.501 1.00 67.78  ? 92  LEU D O     1 
ATOM   2625  C CB    . LEU B 2 110 ? 132.650 125.979 199.497 1.00 67.78  ? 92  LEU D CB    1 
ATOM   2626  C CG    . LEU B 2 110 ? 131.931 126.223 200.827 1.00 67.78  ? 92  LEU D CG    1 
ATOM   2627  C CD1   . LEU B 2 110 ? 132.827 125.838 201.995 1.00 67.78  ? 92  LEU D CD1   1 
ATOM   2628  C CD2   . LEU B 2 110 ? 131.485 127.674 200.956 1.00 67.78  ? 92  LEU D CD2   1 
ATOM   2629  N N     . GLU B 2 111 ? 133.098 124.899 196.450 1.00 71.11  ? 93  GLU D N     1 
ATOM   2630  C CA    . GLU B 2 111 ? 133.794 124.929 195.171 1.00 71.11  ? 93  GLU D CA    1 
ATOM   2631  C C     . GLU B 2 111 ? 132.857 125.053 193.973 1.00 71.11  ? 93  GLU D C     1 
ATOM   2632  O O     . GLU B 2 111 ? 133.345 125.257 192.857 1.00 71.11  ? 93  GLU D O     1 
ATOM   2633  C CB    . GLU B 2 111 ? 134.643 123.665 195.014 1.00 71.11  ? 93  GLU D CB    1 
ATOM   2634  C CG    . GLU B 2 111 ? 133.830 122.402 194.741 1.00 71.11  ? 93  GLU D CG    1 
ATOM   2635  C CD    . GLU B 2 111 ? 134.530 121.136 195.200 1.00 71.11  ? 93  GLU D CD    1 
ATOM   2636  O OE1   . GLU B 2 111 ? 134.920 121.058 196.385 1.00 71.11  ? 93  GLU D OE1   1 
ATOM   2637  O OE2   . GLU B 2 111 ? 134.689 120.214 194.373 1.00 71.11  ? 93  GLU D OE2   1 
ATOM   2638  N N     . THR B 2 112 ? 131.544 124.922 194.165 1.00 62.83  ? 94  THR D N     1 
ATOM   2639  C CA    . THR B 2 112 ? 130.616 124.958 193.040 1.00 62.83  ? 94  THR D CA    1 
ATOM   2640  C C     . THR B 2 112 ? 130.577 126.373 192.456 1.00 62.83  ? 94  THR D C     1 
ATOM   2641  O O     . THR B 2 112 ? 130.495 127.340 193.223 1.00 62.83  ? 94  THR D O     1 
ATOM   2642  C CB    . THR B 2 112 ? 129.218 124.538 193.497 1.00 62.83  ? 94  THR D CB    1 
ATOM   2643  O OG1   . THR B 2 112 ? 129.283 123.257 194.136 1.00 62.83  ? 94  THR D OG1   1 
ATOM   2644  C CG2   . THR B 2 112 ? 128.260 124.450 192.324 1.00 62.83  ? 94  THR D CG2   1 
ATOM   2645  N N     . PRO B 2 113 ? 130.632 126.555 191.130 1.00 60.02  ? 95  PRO D N     1 
ATOM   2646  C CA    . PRO B 2 113 ? 130.495 127.913 190.596 1.00 60.02  ? 95  PRO D CA    1 
ATOM   2647  C C     . PRO B 2 113 ? 129.072 128.423 190.745 1.00 60.02  ? 95  PRO D C     1 
ATOM   2648  O O     . PRO B 2 113 ? 128.122 127.665 190.947 1.00 60.02  ? 95  PRO D O     1 
ATOM   2649  C CB    . PRO B 2 113 ? 130.881 127.773 189.120 1.00 60.02  ? 95  PRO D CB    1 
ATOM   2650  C CG    . PRO B 2 113 ? 130.685 126.370 188.801 1.00 60.02  ? 95  PRO D CG    1 
ATOM   2651  C CD    . PRO B 2 113 ? 130.940 125.601 190.046 1.00 60.02  ? 95  PRO D CD    1 
ATOM   2652  N N     . PHE B 2 114 ? 128.946 129.744 190.657 1.00 51.19  ? 96  PHE D N     1 
ATOM   2653  C CA    . PHE B 2 114 ? 127.664 130.423 190.753 1.00 51.19  ? 96  PHE D CA    1 
ATOM   2654  C C     . PHE B 2 114 ? 127.710 131.635 189.841 1.00 51.19  ? 96  PHE D C     1 
ATOM   2655  O O     . PHE B 2 114 ? 128.754 132.282 189.720 1.00 51.19  ? 96  PHE D O     1 
ATOM   2656  C CB    . PHE B 2 114 ? 127.363 130.840 192.199 1.00 51.19  ? 96  PHE D CB    1 
ATOM   2657  C CG    . PHE B 2 114 ? 126.068 131.587 192.366 1.00 51.19  ? 96  PHE D CG    1 
ATOM   2658  C CD1   . PHE B 2 114 ? 124.869 130.906 192.465 1.00 51.19  ? 96  PHE D CD1   1 
ATOM   2659  C CD2   . PHE B 2 114 ? 126.053 132.969 192.443 1.00 51.19  ? 96  PHE D CD2   1 
ATOM   2660  C CE1   . PHE B 2 114 ? 123.680 131.589 192.624 1.00 51.19  ? 96  PHE D CE1   1 
ATOM   2661  C CE2   . PHE B 2 114 ? 124.866 133.655 192.601 1.00 51.19  ? 96  PHE D CE2   1 
ATOM   2662  C CZ    . PHE B 2 114 ? 123.679 132.965 192.692 1.00 51.19  ? 96  PHE D CZ    1 
ATOM   2663  N N     . ALA B 2 115 ? 126.583 131.922 189.193 1.00 51.23  ? 97  ALA D N     1 
ATOM   2664  C CA    . ALA B 2 115 ? 126.423 133.105 188.361 1.00 51.23  ? 97  ALA D CA    1 
ATOM   2665  C C     . ALA B 2 115 ? 125.112 133.782 188.717 1.00 51.23  ? 97  ALA D C     1 
ATOM   2666  O O     . ALA B 2 115 ? 124.143 133.122 189.097 1.00 51.23  ? 97  ALA D O     1 
ATOM   2667  C CB    . ALA B 2 115 ? 126.444 132.760 186.870 1.00 51.23  ? 97  ALA D CB    1 
ATOM   2668  N N     . MET B 2 116 ? 125.098 135.106 188.585 1.00 50.91  ? 98  MET D N     1 
ATOM   2669  C CA    . MET B 2 116 ? 123.957 135.938 188.937 1.00 50.91  ? 98  MET D CA    1 
ATOM   2670  C C     . MET B 2 116 ? 123.725 136.944 187.825 1.00 50.91  ? 98  MET D C     1 
ATOM   2671  O O     . MET B 2 116 ? 124.670 137.402 187.178 1.00 50.91  ? 98  MET D O     1 
ATOM   2672  C CB    . MET B 2 116 ? 124.192 136.668 190.264 1.00 50.91  ? 98  MET D CB    1 
ATOM   2673  C CG    . MET B 2 116 ? 122.928 137.246 190.886 1.00 50.91  ? 98  MET D CG    1 
ATOM   2674  S SD    . MET B 2 116 ? 123.087 138.144 192.456 1.00 50.91  ? 98  MET D SD    1 
ATOM   2675  C CE    . MET B 2 116 ? 124.849 138.156 192.790 1.00 50.91  ? 98  MET D CE    1 
ATOM   2676  N N     . ILE B 2 117 ? 122.459 137.279 187.597 1.00 55.51  ? 99  ILE D N     1 
ATOM   2677  C CA    . ILE B 2 117 ? 122.134 138.306 186.613 1.00 55.51  ? 99  ILE D CA    1 
ATOM   2678  C C     . ILE B 2 117 ? 120.745 138.846 186.923 1.00 55.51  ? 99  ILE D C     1 
ATOM   2679  O O     . ILE B 2 117 ? 119.869 138.114 187.390 1.00 55.51  ? 99  ILE D O     1 
ATOM   2680  C CB    . ILE B 2 117 ? 122.254 137.751 185.170 1.00 55.51  ? 99  ILE D CB    1 
ATOM   2681  C CG1   . ILE B 2 117 ? 121.835 138.805 184.144 1.00 55.51  ? 99  ILE D CG1   1 
ATOM   2682  C CG2   . ILE B 2 117 ? 121.437 136.466 184.977 1.00 55.51  ? 99  ILE D CG2   1 
ATOM   2683  C CD1   . ILE B 2 117 ? 122.492 138.647 182.788 1.00 55.51  ? 99  ILE D CD1   1 
ATOM   2684  N N     . ALA B 2 118 ? 120.565 140.144 186.695 1.00 59.83  ? 100 ALA D N     1 
ATOM   2685  C CA    . ALA B 2 118 ? 119.265 140.788 186.788 1.00 59.83  ? 100 ALA D CA    1 
ATOM   2686  C C     . ALA B 2 118 ? 118.555 140.719 185.442 1.00 59.83  ? 100 ALA D C     1 
ATOM   2687  O O     . ALA B 2 118 ? 119.180 140.591 184.388 1.00 59.83  ? 100 ALA D O     1 
ATOM   2688  C CB    . ALA B 2 118 ? 119.411 142.244 187.230 1.00 59.83  ? 100 ALA D CB    1 
ATOM   2689  N N     . GLY B 2 119 ? 117.224 140.798 185.494 1.00 61.82  ? 101 GLY D N     1 
ATOM   2690  C CA    . GLY B 2 119 ? 116.439 140.734 184.274 1.00 61.82  ? 101 GLY D CA    1 
ATOM   2691  C C     . GLY B 2 119 ? 116.694 141.895 183.335 1.00 61.82  ? 101 GLY D C     1 
ATOM   2692  O O     . GLY B 2 119 ? 116.637 141.732 182.114 1.00 61.82  ? 101 GLY D O     1 
ATOM   2693  N N     . SER B 2 120 ? 116.977 143.076 183.885 1.00 62.32  ? 102 SER D N     1 
ATOM   2694  C CA    . SER B 2 120 ? 117.252 144.270 183.096 1.00 62.32  ? 102 SER D CA    1 
ATOM   2695  C C     . SER B 2 120 ? 118.721 144.428 182.714 1.00 62.32  ? 102 SER D C     1 
ATOM   2696  O O     . SER B 2 120 ? 119.036 145.306 181.904 1.00 62.32  ? 102 SER D O     1 
ATOM   2697  C CB    . SER B 2 120 ? 116.798 145.515 183.864 1.00 62.32  ? 102 SER D CB    1 
ATOM   2698  O OG    . SER B 2 120 ? 116.814 146.660 183.031 1.00 62.32  ? 102 SER D OG    1 
ATOM   2699  N N     . GLU B 2 121 ? 119.627 143.613 183.264 1.00 63.05  ? 103 GLU D N     1 
ATOM   2700  C CA    . GLU B 2 121 ? 121.046 143.779 182.962 1.00 63.05  ? 103 GLU D CA    1 
ATOM   2701  C C     . GLU B 2 121 ? 121.345 143.387 181.521 1.00 63.05  ? 103 GLU D C     1 
ATOM   2702  O O     . GLU B 2 121 ? 122.267 143.942 180.912 1.00 63.05  ? 103 GLU D O     1 
ATOM   2703  C CB    . GLU B 2 121 ? 121.872 142.971 183.982 1.00 63.05  ? 103 GLU D CB    1 
ATOM   2704  C CG    . GLU B 2 121 ? 123.417 143.206 184.074 1.00 63.05  ? 103 GLU D CG    1 
ATOM   2705  C CD    . GLU B 2 121 ? 124.278 142.789 182.877 1.00 63.05  ? 103 GLU D CD    1 
ATOM   2706  O OE1   . GLU B 2 121 ? 123.855 141.968 182.039 1.00 63.05  ? 103 GLU D OE1   1 
ATOM   2707  O OE2   . GLU B 2 121 ? 125.411 143.305 182.775 1.00 63.05  ? 103 GLU D OE2   1 
ATOM   2708  N N     . ILE B 2 122 ? 120.591 142.437 180.959 1.00 63.37  ? 104 ILE D N     1 
ATOM   2709  C CA    . ILE B 2 122 ? 120.811 142.006 179.578 1.00 63.37  ? 104 ILE D CA    1 
ATOM   2710  C C     . ILE B 2 122 ? 120.546 143.124 178.577 1.00 63.37  ? 104 ILE D C     1 
ATOM   2711  O O     . ILE B 2 122 ? 121.073 143.082 177.460 1.00 63.37  ? 104 ILE D O     1 
ATOM   2712  C CB    . ILE B 2 122 ? 119.938 140.778 179.212 1.00 63.37  ? 104 ILE D CB    1 
ATOM   2713  C CG1   . ILE B 2 122 ? 118.426 141.079 179.364 1.00 63.37  ? 104 ILE D CG1   1 
ATOM   2714  C CG2   . ILE B 2 122 ? 120.387 139.555 180.037 1.00 63.37  ? 104 ILE D CG2   1 
ATOM   2715  C CD1   . ILE B 2 122 ? 117.532 139.866 179.493 1.00 63.37  ? 104 ILE D CD1   1 
ATOM   2716  N N     . PHE B 2 123 ? 119.739 144.127 178.944 1.00 66.43  ? 105 PHE D N     1 
ATOM   2717  C CA    . PHE B 2 123 ? 119.502 145.310 178.125 1.00 66.43  ? 105 PHE D CA    1 
ATOM   2718  C C     . PHE B 2 123 ? 120.508 146.429 178.397 1.00 66.43  ? 105 PHE D C     1 
ATOM   2719  O O     . PHE B 2 123 ? 120.194 147.608 178.184 1.00 66.43  ? 105 PHE D O     1 
ATOM   2720  C CB    . PHE B 2 123 ? 118.074 145.809 178.349 1.00 66.43  ? 105 PHE D CB    1 
ATOM   2721  C CG    . PHE B 2 123 ? 117.024 144.786 178.031 1.00 66.43  ? 105 PHE D CG    1 
ATOM   2722  C CD1   . PHE B 2 123 ? 116.576 144.619 176.733 1.00 66.43  ? 105 PHE D CD1   1 
ATOM   2723  C CD2   . PHE B 2 123 ? 116.490 143.986 179.027 1.00 66.43  ? 105 PHE D CD2   1 
ATOM   2724  C CE1   . PHE B 2 123 ? 115.611 143.681 176.435 1.00 66.43  ? 105 PHE D CE1   1 
ATOM   2725  C CE2   . PHE B 2 123 ? 115.525 143.044 178.733 1.00 66.43  ? 105 PHE D CE2   1 
ATOM   2726  C CZ    . PHE B 2 123 ? 115.089 142.889 177.434 1.00 66.43  ? 105 PHE D CZ    1 
ATOM   2727  N N     . SER B 2 124 ? 121.715 146.094 178.867 1.00 73.36  ? 106 SER D N     1 
ATOM   2728  C CA    . SER B 2 124 ? 122.758 147.099 179.048 1.00 73.36  ? 106 SER D CA    1 
ATOM   2729  C C     . SER B 2 124 ? 123.272 147.668 177.728 1.00 73.36  ? 106 SER D C     1 
ATOM   2730  O O     . SER B 2 124 ? 123.896 148.735 177.741 1.00 73.36  ? 106 SER D O     1 
ATOM   2731  C CB    . SER B 2 124 ? 123.931 146.506 179.834 1.00 73.36  ? 106 SER D CB    1 
ATOM   2732  O OG    . SER B 2 124 ? 123.684 146.551 181.228 1.00 73.36  ? 106 SER D OG    1 
ATOM   2733  N N     . LEU B 2 125 ? 123.054 146.978 176.605 1.00 77.20  ? 107 LEU D N     1 
ATOM   2734  C CA    . LEU B 2 125 ? 123.392 147.372 175.235 1.00 77.20  ? 107 LEU D CA    1 
ATOM   2735  C C     . LEU B 2 125 ? 124.880 147.224 174.916 1.00 77.20  ? 107 LEU D C     1 
ATOM   2736  O O     . LEU B 2 125 ? 125.265 147.485 173.769 1.00 77.20  ? 107 LEU D O     1 
ATOM   2737  C CB    . LEU B 2 125 ? 122.964 148.812 174.897 1.00 77.20  ? 107 LEU D CB    1 
ATOM   2738  C CG    . LEU B 2 125 ? 121.553 149.256 175.304 1.00 77.20  ? 107 LEU D CG    1 
ATOM   2739  C CD1   . LEU B 2 125 ? 121.254 150.634 174.743 1.00 77.20  ? 107 LEU D CD1   1 
ATOM   2740  C CD2   . LEU B 2 125 ? 120.498 148.259 174.849 1.00 77.20  ? 107 LEU D CD2   1 
ATOM   2741  N N     . GLU B 2 126 ? 125.729 146.823 175.868 1.00 84.38  ? 108 GLU D N     1 
ATOM   2742  C CA    . GLU B 2 126 ? 127.109 146.491 175.526 1.00 84.38  ? 108 GLU D CA    1 
ATOM   2743  C C     . GLU B 2 126 ? 127.163 145.274 174.612 1.00 84.38  ? 108 GLU D C     1 
ATOM   2744  O O     . GLU B 2 126 ? 127.977 145.223 173.682 1.00 84.38  ? 108 GLU D O     1 
ATOM   2745  C CB    . GLU B 2 126 ? 127.921 146.240 176.796 1.00 84.38  ? 108 GLU D CB    1 
ATOM   2746  C CG    . GLU B 2 126 ? 128.245 147.495 177.586 1.00 84.38  ? 108 GLU D CG    1 
ATOM   2747  C CD    . GLU B 2 126 ? 129.578 148.099 177.193 1.00 84.38  ? 108 GLU D CD    1 
ATOM   2748  O OE1   . GLU B 2 126 ? 129.647 148.751 176.130 1.00 84.38  ? 108 GLU D OE1   1 
ATOM   2749  O OE2   . GLU B 2 126 ? 130.557 147.923 177.948 1.00 84.38  ? 108 GLU D OE2   1 
ATOM   2750  N N     . MET B 2 127 ? 126.309 144.285 174.872 1.00 78.75  ? 109 MET D N     1 
ATOM   2751  C CA    . MET B 2 127 ? 126.191 143.084 174.060 1.00 78.75  ? 109 MET D CA    1 
ATOM   2752  C C     . MET B 2 127 ? 124.720 142.696 174.014 1.00 78.75  ? 109 MET D C     1 
ATOM   2753  O O     . MET B 2 127 ? 123.900 143.202 174.786 1.00 78.75  ? 109 MET D O     1 
ATOM   2754  C CB    . MET B 2 127 ? 127.050 141.932 174.611 1.00 78.75  ? 109 MET D CB    1 
ATOM   2755  C CG    . MET B 2 127 ? 127.131 141.847 176.133 1.00 78.75  ? 109 MET D CG    1 
ATOM   2756  S SD    . MET B 2 127 ? 128.022 140.381 176.683 1.00 78.75  ? 109 MET D SD    1 
ATOM   2757  C CE    . MET B 2 127 ? 128.018 140.627 178.456 1.00 78.75  ? 109 MET D CE    1 
ATOM   2758  N N     . SER B 2 128 ? 124.387 141.794 173.094 1.00 72.18  ? 110 SER D N     1 
ATOM   2759  C CA    . SER B 2 128 ? 123.001 141.404 172.884 1.00 72.18  ? 110 SER D CA    1 
ATOM   2760  C C     . SER B 2 128 ? 122.458 140.655 174.101 1.00 72.18  ? 110 SER D C     1 
ATOM   2761  O O     . SER B 2 128 ? 123.187 140.307 175.035 1.00 72.18  ? 110 SER D O     1 
ATOM   2762  C CB    . SER B 2 128 ? 122.876 140.537 171.633 1.00 72.18  ? 110 SER D CB    1 
ATOM   2763  O OG    . SER B 2 128 ? 121.561 140.590 171.107 1.00 72.18  ? 110 SER D OG    1 
ATOM   2764  N N     . LYS B 2 129 ? 121.145 140.415 174.082 1.00 64.80  ? 111 LYS D N     1 
ATOM   2765  C CA    . LYS B 2 129 ? 120.504 139.701 175.183 1.00 64.80  ? 111 LYS D CA    1 
ATOM   2766  C C     . LYS B 2 129 ? 121.002 138.265 175.256 1.00 64.80  ? 111 LYS D C     1 
ATOM   2767  O O     . LYS B 2 129 ? 121.395 137.779 176.325 1.00 64.80  ? 111 LYS D O     1 
ATOM   2768  C CB    . LYS B 2 129 ? 118.978 139.706 175.025 1.00 64.80  ? 111 LYS D CB    1 
ATOM   2769  C CG    . LYS B 2 129 ? 118.307 141.059 174.725 1.00 64.80  ? 111 LYS D CG    1 
ATOM   2770  C CD    . LYS B 2 129 ? 116.806 140.906 174.442 1.00 64.80  ? 111 LYS D CD    1 
ATOM   2771  C CE    . LYS B 2 129 ? 116.503 140.210 173.115 1.00 64.80  ? 111 LYS D CE    1 
ATOM   2772  N NZ    . LYS B 2 129 ? 115.164 140.577 172.583 1.00 64.80  ? 111 LYS D NZ    1 
ATOM   2773  N N     . THR B 2 130 ? 121.000 137.574 174.116 1.00 65.30  ? 112 THR D N     1 
ATOM   2774  C CA    . THR B 2 130 ? 121.395 136.174 174.098 1.00 65.30  ? 112 THR D CA    1 
ATOM   2775  C C     . THR B 2 130 ? 122.880 136.006 174.371 1.00 65.30  ? 112 THR D C     1 
ATOM   2776  O O     . THR B 2 130 ? 123.281 134.999 174.957 1.00 65.30  ? 112 THR D O     1 
ATOM   2777  C CB    . THR B 2 130 ? 121.022 135.540 172.760 1.00 65.30  ? 112 THR D CB    1 
ATOM   2778  O OG1   . THR B 2 130 ? 121.730 136.196 171.701 1.00 65.30  ? 112 THR D OG1   1 
ATOM   2779  C CG2   . THR B 2 130 ? 119.521 135.643 172.523 1.00 65.30  ? 112 THR D CG2   1 
ATOM   2780  N N     . GLU B 2 131 ? 123.709 136.971 173.967 1.00 70.67  ? 113 GLU D N     1 
ATOM   2781  C CA    . GLU B 2 131 ? 125.131 136.891 174.286 1.00 70.67  ? 113 GLU D CA    1 
ATOM   2782  C C     . GLU B 2 131 ? 125.363 136.995 175.789 1.00 70.67  ? 113 GLU D C     1 
ATOM   2783  O O     . GLU B 2 131 ? 126.163 136.238 176.355 1.00 70.67  ? 113 GLU D O     1 
ATOM   2784  C CB    . GLU B 2 131 ? 125.895 137.988 173.537 1.00 70.67  ? 113 GLU D CB    1 
ATOM   2785  C CG    . GLU B 2 131 ? 127.420 138.012 173.740 1.00 70.67  ? 113 GLU D CG    1 
ATOM   2786  C CD    . GLU B 2 131 ? 128.098 136.696 173.400 1.00 70.67  ? 113 GLU D CD    1 
ATOM   2787  O OE1   . GLU B 2 131 ? 127.580 135.967 172.529 1.00 70.67  ? 113 GLU D OE1   1 
ATOM   2788  O OE2   . GLU B 2 131 ? 129.145 136.389 174.006 1.00 70.67  ? 113 GLU D OE2   1 
ATOM   2789  N N     . ALA B 2 132 ? 124.663 137.918 176.452 1.00 67.58  ? 114 ALA D N     1 
ATOM   2790  C CA    . ALA B 2 132 ? 124.781 138.039 177.901 1.00 67.58  ? 114 ALA D CA    1 
ATOM   2791  C C     . ALA B 2 132 ? 124.260 136.791 178.600 1.00 67.58  ? 114 ALA D C     1 
ATOM   2792  O O     . ALA B 2 132 ? 124.848 136.330 179.585 1.00 67.58  ? 114 ALA D O     1 
ATOM   2793  C CB    . ALA B 2 132 ? 124.029 139.278 178.386 1.00 67.58  ? 114 ALA D CB    1 
ATOM   2794  N N     . LEU B 2 133 ? 123.157 136.226 178.101 1.00 61.11  ? 115 LEU D N     1 
ATOM   2795  C CA    . LEU B 2 133 ? 122.635 134.997 178.691 1.00 61.11  ? 115 LEU D CA    1 
ATOM   2796  C C     . LEU B 2 133 ? 123.595 133.830 178.485 1.00 61.11  ? 115 LEU D C     1 
ATOM   2797  O O     . LEU B 2 133 ? 123.748 132.984 179.372 1.00 61.11  ? 115 LEU D O     1 
ATOM   2798  C CB    . LEU B 2 133 ? 121.259 134.680 178.107 1.00 61.11  ? 115 LEU D CB    1 
ATOM   2799  C CG    . LEU B 2 133 ? 120.126 135.556 178.648 1.00 61.11  ? 115 LEU D CG    1 
ATOM   2800  C CD1   . LEU B 2 133 ? 118.995 135.668 177.641 1.00 61.11  ? 115 LEU D CD1   1 
ATOM   2801  C CD2   . LEU B 2 133 ? 119.611 135.011 179.971 1.00 61.11  ? 115 LEU D CD2   1 
ATOM   2802  N N     . THR B 2 134 ? 124.256 133.771 177.325 1.00 64.28  ? 116 THR D N     1 
ATOM   2803  C CA    . THR B 2 134 ? 125.249 132.729 177.088 1.00 64.28  ? 116 THR D CA    1 
ATOM   2804  C C     . THR B 2 134 ? 126.432 132.881 178.031 1.00 64.28  ? 116 THR D C     1 
ATOM   2805  O O     . THR B 2 134 ? 126.954 131.887 178.549 1.00 64.28  ? 116 THR D O     1 
ATOM   2806  C CB    . THR B 2 134 ? 125.734 132.775 175.638 1.00 64.28  ? 116 THR D CB    1 
ATOM   2807  O OG1   . THR B 2 134 ? 124.648 133.107 174.768 1.00 64.28  ? 116 THR D OG1   1 
ATOM   2808  C CG2   . THR B 2 134 ? 126.311 131.427 175.226 1.00 64.28  ? 116 THR D CG2   1 
ATOM   2809  N N     . GLN B 2 135 ? 126.875 134.120 178.257 1.00 68.20  ? 117 GLN D N     1 
ATOM   2810  C CA    . GLN B 2 135 ? 127.973 134.350 179.190 1.00 68.20  ? 117 GLN D CA    1 
ATOM   2811  C C     . GLN B 2 135 ? 127.576 133.965 180.610 1.00 68.20  ? 117 GLN D C     1 
ATOM   2812  O O     . GLN B 2 135 ? 128.378 133.385 181.350 1.00 68.20  ? 117 GLN D O     1 
ATOM   2813  C CB    . GLN B 2 135 ? 128.413 135.815 179.137 1.00 68.20  ? 117 GLN D CB    1 
ATOM   2814  C CG    . GLN B 2 135 ? 129.150 136.227 177.862 1.00 68.20  ? 117 GLN D CG    1 
ATOM   2815  C CD    . GLN B 2 135 ? 130.503 135.558 177.712 1.00 68.20  ? 117 GLN D CD    1 
ATOM   2816  O OE1   . GLN B 2 135 ? 131.026 134.970 178.658 1.00 68.20  ? 117 GLN D OE1   1 
ATOM   2817  N NE2   . GLN B 2 135 ? 131.078 135.646 176.518 1.00 68.20  ? 117 GLN D NE2   1 
ATOM   2818  N N     . SER B 2 136 ? 126.339 134.275 181.005 1.00 59.21  ? 118 SER D N     1 
ATOM   2819  C CA    . SER B 2 136 ? 125.866 133.884 182.330 1.00 59.21  ? 118 SER D CA    1 
ATOM   2820  C C     . SER B 2 136 ? 125.784 132.367 182.465 1.00 59.21  ? 118 SER D C     1 
ATOM   2821  O O     . SER B 2 136 ? 126.133 131.813 183.514 1.00 59.21  ? 118 SER D O     1 
ATOM   2822  C CB    . SER B 2 136 ? 124.506 134.521 182.607 1.00 59.21  ? 118 SER D CB    1 
ATOM   2823  O OG    . SER B 2 136 ? 124.565 135.929 182.470 1.00 59.21  ? 118 SER D OG    1 
ATOM   2824  N N     . PHE B 2 137 ? 125.316 131.681 181.419 1.00 57.39  ? 119 PHE D N     1 
ATOM   2825  C CA    . PHE B 2 137 ? 125.252 130.222 181.455 1.00 57.39  ? 119 PHE D CA    1 
ATOM   2826  C C     . PHE B 2 137 ? 126.642 129.605 181.535 1.00 57.39  ? 119 PHE D C     1 
ATOM   2827  O O     . PHE B 2 137 ? 126.866 128.657 182.296 1.00 57.39  ? 119 PHE D O     1 
ATOM   2828  C CB    . PHE B 2 137 ? 124.516 129.688 180.220 1.00 57.39  ? 119 PHE D CB    1 
ATOM   2829  C CG    . PHE B 2 137 ? 123.037 129.487 180.422 1.00 57.39  ? 119 PHE D CG    1 
ATOM   2830  C CD1   . PHE B 2 137 ? 122.569 128.477 181.242 1.00 57.39  ? 119 PHE D CD1   1 
ATOM   2831  C CD2   . PHE B 2 137 ? 122.119 130.305 179.789 1.00 57.39  ? 119 PHE D CD2   1 
ATOM   2832  C CE1   . PHE B 2 137 ? 121.221 128.284 181.428 1.00 57.39  ? 119 PHE D CE1   1 
ATOM   2833  C CE2   . PHE B 2 137 ? 120.765 130.117 179.973 1.00 57.39  ? 119 PHE D CE2   1 
ATOM   2834  C CZ    . PHE B 2 137 ? 120.318 129.105 180.796 1.00 57.39  ? 119 PHE D CZ    1 
ATOM   2835  N N     . ARG B 2 138 ? 127.589 130.123 180.753 1.00 68.88  ? 120 ARG D N     1 
ATOM   2836  C CA    . ARG B 2 138 ? 128.941 129.581 180.780 1.00 68.88  ? 120 ARG D CA    1 
ATOM   2837  C C     . ARG B 2 138 ? 129.645 129.890 182.096 1.00 68.88  ? 120 ARG D C     1 
ATOM   2838  O O     . ARG B 2 138 ? 130.499 129.112 182.534 1.00 68.88  ? 120 ARG D O     1 
ATOM   2839  C CB    . ARG B 2 138 ? 129.741 130.125 179.597 1.00 68.88  ? 120 ARG D CB    1 
ATOM   2840  C CG    . ARG B 2 138 ? 129.266 129.602 178.248 1.00 68.88  ? 120 ARG D CG    1 
ATOM   2841  C CD    . ARG B 2 138 ? 130.014 130.249 177.094 1.00 68.88  ? 120 ARG D CD    1 
ATOM   2842  N NE    . ARG B 2 138 ? 131.397 129.794 177.011 1.00 68.88  ? 120 ARG D NE    1 
ATOM   2843  C CZ    . ARG B 2 138 ? 131.794 128.606 176.567 1.00 68.88  ? 120 ARG D CZ    1 
ATOM   2844  N NH1   . ARG B 2 138 ? 130.935 127.691 176.136 1.00 68.88  ? 120 ARG D NH1   1 
ATOM   2845  N NH2   . ARG B 2 138 ? 133.093 128.324 176.556 1.00 68.88  ? 120 ARG D NH2   1 
ATOM   2846  N N     . LYS B 2 139 ? 129.309 131.014 182.735 1.00 63.02  ? 121 LYS D N     1 
ATOM   2847  C CA    . LYS B 2 139 ? 129.913 131.343 184.023 1.00 63.02  ? 121 LYS D CA    1 
ATOM   2848  C C     . LYS B 2 139 ? 129.528 130.341 185.105 1.00 63.02  ? 121 LYS D C     1 
ATOM   2849  O O     . LYS B 2 139 ? 130.318 130.092 186.023 1.00 63.02  ? 121 LYS D O     1 
ATOM   2850  C CB    . LYS B 2 139 ? 129.507 132.754 184.455 1.00 63.02  ? 121 LYS D CB    1 
ATOM   2851  C CG    . LYS B 2 139 ? 130.406 133.865 183.917 1.00 63.02  ? 121 LYS D CG    1 
ATOM   2852  C CD    . LYS B 2 139 ? 130.156 135.203 184.607 1.00 63.02  ? 121 LYS D CD    1 
ATOM   2853  C CE    . LYS B 2 139 ? 128.799 135.794 184.252 1.00 63.02  ? 121 LYS D CE    1 
ATOM   2854  N NZ    . LYS B 2 139 ? 128.601 137.128 184.880 1.00 63.02  ? 121 LYS D NZ    1 
ATOM   2855  N N     . ALA B 2 140 ? 128.330 129.754 185.015 1.00 56.61  ? 122 ALA D N     1 
ATOM   2856  C CA    . ALA B 2 140 ? 127.811 128.833 186.021 1.00 56.61  ? 122 ALA D CA    1 
ATOM   2857  C C     . ALA B 2 140 ? 128.164 127.373 185.737 1.00 56.61  ? 122 ALA D C     1 
ATOM   2858  O O     . ALA B 2 140 ? 127.430 126.473 186.165 1.00 56.61  ? 122 ALA D O     1 
ATOM   2859  C CB    . ALA B 2 140 ? 126.297 129.004 186.137 1.00 56.61  ? 122 ALA D CB    1 
ATOM   2860  N N     . ILE B 2 141 ? 129.255 127.115 185.013 1.00 65.01  ? 123 ILE D N     1 
ATOM   2861  C CA    . ILE B 2 141 ? 129.786 125.774 184.779 1.00 65.01  ? 123 ILE D CA    1 
ATOM   2862  C C     . ILE B 2 141 ? 131.267 125.826 185.121 1.00 65.01  ? 123 ILE D C     1 
ATOM   2863  O O     . ILE B 2 141 ? 131.927 126.834 184.847 1.00 65.01  ? 123 ILE D O     1 
ATOM   2864  C CB    . ILE B 2 141 ? 129.578 125.298 183.320 1.00 65.01  ? 123 ILE D CB    1 
ATOM   2865  C CG1   . ILE B 2 141 ? 128.094 125.255 182.917 1.00 65.01  ? 123 ILE D CG1   1 
ATOM   2866  C CG2   . ILE B 2 141 ? 130.203 123.922 183.107 1.00 65.01  ? 123 ILE D CG2   1 
ATOM   2867  C CD1   . ILE B 2 141 ? 127.871 125.430 181.427 1.00 65.01  ? 123 ILE D CD1   1 
ATOM   2868  N N     . GLY B 2 142 ? 131.786 124.749 185.726 1.00 74.22  ? 124 GLY D N     1 
ATOM   2869  C CA    . GLY B 2 142 ? 133.161 124.722 186.187 1.00 74.22  ? 124 GLY D CA    1 
ATOM   2870  C C     . GLY B 2 142 ? 133.829 123.408 185.841 1.00 74.22  ? 124 GLY D C     1 
ATOM   2871  O O     . GLY B 2 142 ? 133.177 122.427 185.483 1.00 74.22  ? 124 GLY D O     1 
ATOM   2872  N N     . VAL B 2 143 ? 135.159 123.418 185.937 1.00 82.35  ? 125 VAL D N     1 
ATOM   2873  C CA    . VAL B 2 143 ? 135.997 122.241 185.721 1.00 82.35  ? 125 VAL D CA    1 
ATOM   2874  C C     . VAL B 2 143 ? 137.006 122.186 186.858 1.00 82.35  ? 125 VAL D C     1 
ATOM   2875  O O     . VAL B 2 143 ? 137.746 123.152 187.078 1.00 82.35  ? 125 VAL D O     1 
ATOM   2876  C CB    . VAL B 2 143 ? 136.716 122.287 184.360 1.00 82.35  ? 125 VAL D CB    1 
ATOM   2877  C CG1   . VAL B 2 143 ? 137.421 120.955 184.070 1.00 82.35  ? 125 VAL D CG1   1 
ATOM   2878  C CG2   . VAL B 2 143 ? 135.729 122.652 183.247 1.00 82.35  ? 125 VAL D CG2   1 
ATOM   2879  N N     . ARG B 2 144 ? 137.039 121.067 187.578 1.00 82.55  ? 126 ARG D N     1 
ATOM   2880  C CA    . ARG B 2 144 ? 138.039 120.850 188.621 1.00 82.55  ? 126 ARG D CA    1 
ATOM   2881  C C     . ARG B 2 144 ? 138.146 119.366 188.970 1.00 82.55  ? 126 ARG D C     1 
ATOM   2882  O O     . ARG B 2 144 ? 137.136 118.669 189.067 1.00 82.55  ? 126 ARG D O     1 
ATOM   2883  C CB    . ARG B 2 144 ? 137.731 121.708 189.871 1.00 82.55  ? 126 ARG D CB    1 
ATOM   2884  C CG    . ARG B 2 144 ? 136.527 121.312 190.772 1.00 82.55  ? 126 ARG D CG    1 
ATOM   2885  C CD    . ARG B 2 144 ? 136.732 121.774 192.211 1.00 82.55  ? 126 ARG D CD    1 
ATOM   2886  N NE    . ARG B 2 144 ? 137.274 123.130 192.299 1.00 82.55  ? 126 ARG D NE    1 
ATOM   2887  C CZ    . ARG B 2 144 ? 137.944 123.637 193.330 1.00 82.55  ? 126 ARG D CZ    1 
ATOM   2888  N NH1   . ARG B 2 144 ? 138.189 122.935 194.429 1.00 82.55  ? 126 ARG D NH1   1 
ATOM   2889  N NH2   . ARG B 2 144 ? 138.378 124.892 193.263 1.00 82.55  ? 126 ARG D NH2   1 
ATOM   2890  N N     . CYS B 2 256 ? 141.080 125.341 189.230 1.00 78.51  ? 238 CYS D N     1 
ATOM   2891  C CA    . CYS B 2 256 ? 139.673 125.396 188.743 1.00 78.51  ? 238 CYS D CA    1 
ATOM   2892  C C     . CYS B 2 256 ? 139.485 126.552 187.768 1.00 78.51  ? 238 CYS D C     1 
ATOM   2893  O O     . CYS B 2 256 ? 140.201 127.550 187.832 1.00 78.51  ? 238 CYS D O     1 
ATOM   2894  C CB    . CYS B 2 256 ? 138.704 125.535 189.917 1.00 78.51  ? 238 CYS D CB    1 
ATOM   2895  S SG    . CYS B 2 256 ? 136.972 125.716 189.433 1.00 78.51  ? 238 CYS D SG    1 
ATOM   2896  N N     . VAL B 2 257 ? 138.520 126.413 186.863 1.00 74.73  ? 239 VAL D N     1 
ATOM   2897  C CA    . VAL B 2 257 ? 138.263 127.432 185.851 1.00 74.73  ? 239 VAL D CA    1 
ATOM   2898  C C     . VAL B 2 257 ? 136.872 127.193 185.280 1.00 74.73  ? 239 VAL D C     1 
ATOM   2899  O O     . VAL B 2 257 ? 136.471 126.050 185.043 1.00 74.73  ? 239 VAL D O     1 
ATOM   2900  C CB    . VAL B 2 257 ? 139.349 127.415 184.746 1.00 74.73  ? 239 VAL D CB    1 
ATOM   2901  C CG1   . VAL B 2 257 ? 139.281 126.135 183.908 1.00 74.73  ? 239 VAL D CG1   1 
ATOM   2902  C CG2   . VAL B 2 257 ? 139.233 128.646 183.855 1.00 74.73  ? 239 VAL D CG2   1 
ATOM   2903  N N     . THR B 2 258 ? 136.144 128.284 185.060 1.00 71.26  ? 240 THR D N     1 
ATOM   2904  C CA    . THR B 2 258 ? 134.825 128.248 184.447 1.00 71.26  ? 240 THR D CA    1 
ATOM   2905  C C     . THR B 2 258 ? 134.946 128.358 182.931 1.00 71.26  ? 240 THR D C     1 
ATOM   2906  O O     . THR B 2 258 ? 135.980 128.760 182.393 1.00 71.26  ? 240 THR D O     1 
ATOM   2907  C CB    . THR B 2 258 ? 133.947 129.380 184.979 1.00 71.26  ? 240 THR D CB    1 
ATOM   2908  O OG1   . THR B 2 258 ? 134.472 130.640 184.543 1.00 71.26  ? 240 THR D OG1   1 
ATOM   2909  C CG2   . THR B 2 258 ? 133.895 129.351 186.499 1.00 71.26  ? 240 THR D CG2   1 
ATOM   2910  N N     . LEU B 2 259 ? 133.864 127.995 182.239 1.00 72.13  ? 241 LEU D N     1 
ATOM   2911  C CA    . LEU B 2 259 ? 133.889 128.032 180.781 1.00 72.13  ? 241 LEU D CA    1 
ATOM   2912  C C     . LEU B 2 259 ? 133.901 129.460 180.254 1.00 72.13  ? 241 LEU D C     1 
ATOM   2913  O O     . LEU B 2 259 ? 134.409 129.704 179.155 1.00 72.13  ? 241 LEU D O     1 
ATOM   2914  C CB    . LEU B 2 259 ? 132.698 127.263 180.209 1.00 72.13  ? 241 LEU D CB    1 
ATOM   2915  C CG    . LEU B 2 259 ? 132.480 125.812 180.659 1.00 72.13  ? 241 LEU D CG    1 
ATOM   2916  C CD1   . LEU B 2 259 ? 131.537 125.112 179.688 1.00 72.13  ? 241 LEU D CD1   1 
ATOM   2917  C CD2   . LEU B 2 259 ? 133.776 125.019 180.811 1.00 72.13  ? 241 LEU D CD2   1 
ATOM   2918  N N     . HIS B 2 260 ? 133.354 130.414 181.011 1.00 68.04  ? 242 HIS D N     1 
ATOM   2919  C CA    . HIS B 2 260 ? 133.546 131.817 180.658 1.00 68.04  ? 242 HIS D CA    1 
ATOM   2920  C C     . HIS B 2 260 ? 135.019 132.196 180.734 1.00 68.04  ? 242 HIS D C     1 
ATOM   2921  O O     . HIS B 2 260 ? 135.526 132.937 179.883 1.00 68.04  ? 242 HIS D O     1 
ATOM   2922  C CB    . HIS B 2 260 ? 132.721 132.714 181.578 1.00 68.04  ? 242 HIS D CB    1 
ATOM   2923  C CG    . HIS B 2 260 ? 132.977 134.175 181.380 1.00 68.04  ? 242 HIS D CG    1 
ATOM   2924  N ND1   . HIS B 2 260 ? 133.212 134.729 180.140 1.00 68.04  ? 242 HIS D ND1   1 
ATOM   2925  C CD2   . HIS B 2 260 ? 133.048 135.196 182.267 1.00 68.04  ? 242 HIS D CD2   1 
ATOM   2926  C CE1   . HIS B 2 260 ? 133.411 136.028 180.271 1.00 68.04  ? 242 HIS D CE1   1 
ATOM   2927  N NE2   . HIS B 2 260 ? 133.316 136.337 181.551 1.00 68.04  ? 242 HIS D NE2   1 
ATOM   2928  N N     . GLU B 2 261 ? 135.725 131.694 181.747 1.00 70.14  ? 243 GLU D N     1 
ATOM   2929  C CA    . GLU B 2 261 ? 137.152 131.965 181.849 1.00 70.14  ? 243 GLU D CA    1 
ATOM   2930  C C     . GLU B 2 261 ? 137.933 131.271 180.739 1.00 70.14  ? 243 GLU D C     1 
ATOM   2931  O O     . GLU B 2 261 ? 138.922 131.825 180.247 1.00 70.14  ? 243 GLU D O     1 
ATOM   2932  C CB    . GLU B 2 261 ? 137.662 131.547 183.227 1.00 70.14  ? 243 GLU D CB    1 
ATOM   2933  C CG    . GLU B 2 261 ? 137.336 132.565 184.314 1.00 70.14  ? 243 GLU D CG    1 
ATOM   2934  C CD    . GLU B 2 261 ? 137.182 131.946 185.689 1.00 70.14  ? 243 GLU D CD    1 
ATOM   2935  O OE1   . GLU B 2 261 ? 137.834 130.918 185.964 1.00 70.14  ? 243 GLU D OE1   1 
ATOM   2936  O OE2   . GLU B 2 261 ? 136.405 132.492 186.500 1.00 70.14  ? 243 GLU D OE2   1 
ATOM   2937  N N     . ILE B 2 262 ? 137.504 130.077 180.321 1.00 69.93  ? 244 ILE D N     1 
ATOM   2938  C CA    . ILE B 2 262 ? 138.140 129.425 179.178 1.00 69.93  ? 244 ILE D CA    1 
ATOM   2939  C C     . ILE B 2 262 ? 137.896 130.238 177.911 1.00 69.93  ? 244 ILE D C     1 
ATOM   2940  O O     . ILE B 2 262 ? 138.774 130.338 177.046 1.00 69.93  ? 244 ILE D O     1 
ATOM   2941  C CB    . ILE B 2 262 ? 137.643 127.969 179.042 1.00 69.93  ? 244 ILE D CB    1 
ATOM   2942  C CG1   . ILE B 2 262 ? 138.270 127.108 180.152 1.00 69.93  ? 244 ILE D CG1   1 
ATOM   2943  C CG2   . ILE B 2 262 ? 137.962 127.388 177.620 1.00 69.93  ? 244 ILE D CG2   1 
ATOM   2944  C CD1   . ILE B 2 262 ? 137.693 125.699 180.298 1.00 69.93  ? 244 ILE D CD1   1 
ATOM   2945  N N     . ASP B 2 263 ? 136.700 130.813 177.772 1.00 68.89  ? 245 ASP D N     1 
ATOM   2946  C CA    . ASP B 2 263 ? 136.418 131.666 176.623 1.00 68.89  ? 245 ASP D CA    1 
ATOM   2947  C C     . ASP B 2 263 ? 137.291 132.914 176.638 1.00 68.89  ? 245 ASP D C     1 
ATOM   2948  O O     . ASP B 2 263 ? 137.777 133.353 175.590 1.00 68.89  ? 245 ASP D O     1 
ATOM   2949  C CB    . ASP B 2 263 ? 134.941 132.055 176.606 1.00 68.89  ? 245 ASP D CB    1 
ATOM   2950  C CG    . ASP B 2 263 ? 134.599 132.992 175.465 1.00 68.89  ? 245 ASP D CG    1 
ATOM   2951  O OD1   . ASP B 2 263 ? 135.240 132.893 174.398 1.00 68.89  ? 245 ASP D OD1   1 
ATOM   2952  O OD2   . ASP B 2 263 ? 133.691 133.832 175.638 1.00 68.89  ? 245 ASP D OD2   1 
ATOM   2953  N N     . VAL B 2 264 ? 137.490 133.501 177.819 1.00 67.58  ? 246 VAL D N     1 
ATOM   2954  C CA    . VAL B 2 264 ? 138.332 134.691 177.929 1.00 67.58  ? 246 VAL D CA    1 
ATOM   2955  C C     . VAL B 2 264 ? 139.782 134.349 177.602 1.00 67.58  ? 246 VAL D C     1 
ATOM   2956  O O     . VAL B 2 264 ? 140.479 135.120 176.931 1.00 67.58  ? 246 VAL D O     1 
ATOM   2957  C CB    . VAL B 2 264 ? 138.189 135.319 179.332 1.00 67.58  ? 246 VAL D CB    1 
ATOM   2958  C CG1   . VAL B 2 264 ? 139.245 136.419 179.565 1.00 67.58  ? 246 VAL D CG1   1 
ATOM   2959  C CG2   . VAL B 2 264 ? 136.766 135.883 179.542 1.00 67.58  ? 246 VAL D CG2   1 
ATOM   2960  N N     . ILE B 2 265 ? 140.264 133.198 178.080 1.00 66.52  ? 247 ILE D N     1 
ATOM   2961  C CA    . ILE B 2 265 ? 141.638 132.787 177.805 1.00 66.52  ? 247 ILE D CA    1 
ATOM   2962  C C     . ILE B 2 265 ? 141.822 132.512 176.315 1.00 66.52  ? 247 ILE D C     1 
ATOM   2963  O O     . ILE B 2 265 ? 142.824 132.919 175.717 1.00 66.52  ? 247 ILE D O     1 
ATOM   2964  C CB    . ILE B 2 265 ? 142.008 131.563 178.671 1.00 66.52  ? 247 ILE D CB    1 
ATOM   2965  C CG1   . ILE B 2 265 ? 142.179 131.980 180.139 1.00 66.52  ? 247 ILE D CG1   1 
ATOM   2966  C CG2   . ILE B 2 265 ? 143.309 130.897 178.184 1.00 66.52  ? 247 ILE D CG2   1 
ATOM   2967  C CD1   . ILE B 2 265 ? 142.016 130.845 181.141 1.00 66.52  ? 247 ILE D CD1   1 
ATOM   2968  N N     . ASN B 2 266 ? 140.860 131.827 175.697 1.00 65.61  ? 248 ASN D N     1 
ATOM   2969  C CA    . ASN B 2 266 ? 140.894 131.494 174.277 1.00 65.61  ? 248 ASN D CA    1 
ATOM   2970  C C     . ASN B 2 266 ? 140.231 132.554 173.395 1.00 65.61  ? 248 ASN D C     1 
ATOM   2971  O O     . ASN B 2 266 ? 139.972 132.284 172.218 1.00 65.61  ? 248 ASN D O     1 
ATOM   2972  C CB    . ASN B 2 266 ? 140.222 130.134 174.054 1.00 65.61  ? 248 ASN D CB    1 
ATOM   2973  C CG    . ASN B 2 266 ? 140.996 128.993 174.682 1.00 65.61  ? 248 ASN D CG    1 
ATOM   2974  O OD1   . ASN B 2 266 ? 141.623 129.157 175.727 1.00 65.61  ? 248 ASN D OD1   1 
ATOM   2975  N ND2   . ASN B 2 266 ? 140.955 127.828 174.046 1.00 65.61  ? 248 ASN D ND2   1 
ATOM   2976  N N     . SER B 2 267 ? 139.957 133.745 173.924 1.00 64.44  ? 249 SER D N     1 
ATOM   2977  C CA    . SER B 2 267 ? 139.297 134.793 173.148 1.00 64.44  ? 249 SER D CA    1 
ATOM   2978  C C     . SER B 2 267 ? 140.185 135.279 172.008 1.00 64.44  ? 249 SER D C     1 
ATOM   2979  O O     . SER B 2 267 ? 139.794 135.229 170.842 1.00 64.44  ? 249 SER D O     1 
ATOM   2980  C CB    . SER B 2 267 ? 138.919 135.973 174.047 1.00 64.44  ? 249 SER D CB    1 
ATOM   2981  O OG    . SER B 2 267 ? 140.047 136.472 174.742 1.00 64.44  ? 249 SER D OG    1 
ATOM   2982  N N     . THR B 2 280 ? 135.024 139.805 172.987 1.00 79.69  ? 262 THR D N     1 
ATOM   2983  C CA    . THR B 2 280 ? 134.031 138.720 173.228 1.00 79.69  ? 262 THR D CA    1 
ATOM   2984  C C     . THR B 2 280 ? 134.017 137.737 172.060 1.00 79.69  ? 262 THR D C     1 
ATOM   2985  O O     . THR B 2 280 ? 134.338 136.559 172.225 1.00 79.69  ? 262 THR D O     1 
ATOM   2986  C CB    . THR B 2 280 ? 132.613 139.296 173.444 1.00 79.69  ? 262 THR D CB    1 
ATOM   2987  O OG1   . THR B 2 280 ? 132.638 140.240 174.521 1.00 79.69  ? 262 THR D OG1   1 
ATOM   2988  C CG2   . THR B 2 280 ? 131.617 138.187 173.763 1.00 79.69  ? 262 THR D CG2   1 
ATOM   2989  N N     . GLY B 2 281 ? 133.644 138.228 170.880 1.00 81.86  ? 263 GLY D N     1 
ATOM   2990  C CA    . GLY B 2 281 ? 133.616 137.387 169.704 1.00 81.86  ? 263 GLY D CA    1 
ATOM   2991  C C     . GLY B 2 281 ? 132.534 136.321 169.790 1.00 81.86  ? 263 GLY D C     1 
ATOM   2992  O O     . GLY B 2 281 ? 131.611 136.382 170.608 1.00 81.86  ? 263 GLY D O     1 
ATOM   2993  N N     . GLU B 2 282 ? 132.675 135.322 168.919 1.00 78.80  ? 264 GLU D N     1 
ATOM   2994  C CA    . GLU B 2 282 ? 131.763 134.189 168.855 1.00 78.80  ? 264 GLU D CA    1 
ATOM   2995  C C     . GLU B 2 282 ? 132.294 133.053 169.716 1.00 78.80  ? 264 GLU D C     1 
ATOM   2996  O O     . GLU B 2 282 ? 133.495 132.769 169.721 1.00 78.80  ? 264 GLU D O     1 
ATOM   2997  C CB    . GLU B 2 282 ? 131.592 133.721 167.405 1.00 78.80  ? 264 GLU D CB    1 
ATOM   2998  C CG    . GLU B 2 282 ? 130.669 132.507 167.179 1.00 78.80  ? 264 GLU D CG    1 
ATOM   2999  C CD    . GLU B 2 282 ? 129.262 132.711 167.709 1.00 78.80  ? 264 GLU D CD    1 
ATOM   3000  O OE1   . GLU B 2 282 ? 129.063 132.584 168.934 1.00 78.80  ? 264 GLU D OE1   1 
ATOM   3001  O OE2   . GLU B 2 282 ? 128.357 132.998 166.898 1.00 78.80  ? 264 GLU D OE2   1 
ATOM   3002  N N     . ILE B 2 283 ? 131.386 132.401 170.440 1.00 74.49  ? 265 ILE D N     1 
ATOM   3003  C CA    . ILE B 2 283 ? 131.736 131.249 171.262 1.00 74.49  ? 265 ILE D CA    1 
ATOM   3004  C C     . ILE B 2 283 ? 131.848 130.056 170.325 1.00 74.49  ? 265 ILE D C     1 
ATOM   3005  O O     . ILE B 2 283 ? 130.852 129.389 170.026 1.00 74.49  ? 265 ILE D O     1 
ATOM   3006  C CB    . ILE B 2 283 ? 130.699 131.006 172.379 1.00 74.49  ? 265 ILE D CB    1 
ATOM   3007  C CG1   . ILE B 2 283 ? 130.753 132.123 173.429 1.00 74.49  ? 265 ILE D CG1   1 
ATOM   3008  C CG2   . ILE B 2 283 ? 130.927 129.653 173.057 1.00 74.49  ? 265 ILE D CG2   1 
ATOM   3009  C CD1   . ILE B 2 283 ? 129.432 132.373 174.114 1.00 74.49  ? 265 ILE D CD1   1 
ATOM   3010  N N     . ARG B 2 284 ? 133.061 129.795 169.846 1.00 80.57  ? 266 ARG D N     1 
ATOM   3011  C CA    . ARG B 2 284 ? 133.272 128.729 168.879 1.00 80.57  ? 266 ARG D CA    1 
ATOM   3012  C C     . ARG B 2 284 ? 133.014 127.371 169.517 1.00 80.57  ? 266 ARG D C     1 
ATOM   3013  O O     . ARG B 2 284 ? 133.215 127.173 170.717 1.00 80.57  ? 266 ARG D O     1 
ATOM   3014  C CB    . ARG B 2 284 ? 134.698 128.776 168.321 1.00 80.57  ? 266 ARG D CB    1 
ATOM   3015  C CG    . ARG B 2 284 ? 135.182 130.148 167.826 1.00 80.57  ? 266 ARG D CG    1 
ATOM   3016  C CD    . ARG B 2 284 ? 134.153 130.921 166.991 1.00 80.57  ? 266 ARG D CD    1 
ATOM   3017  N NE    . ARG B 2 284 ? 133.509 130.111 165.957 1.00 80.57  ? 266 ARG D NE    1 
ATOM   3018  C CZ    . ARG B 2 284 ? 132.859 130.582 164.897 1.00 80.57  ? 266 ARG D CZ    1 
ATOM   3019  N NH1   . ARG B 2 284 ? 132.743 131.882 164.659 1.00 80.57  ? 266 ARG D NH1   1 
ATOM   3020  N NH2   . ARG B 2 284 ? 132.307 129.722 164.046 1.00 80.57  ? 266 ARG D NH2   1 
ATOM   3021  N N     . SER B 2 285 ? 132.553 126.428 168.694 1.00 84.23  ? 267 SER D N     1 
ATOM   3022  C CA    . SER B 2 285 ? 132.265 125.085 169.183 1.00 84.23  ? 267 SER D CA    1 
ATOM   3023  C C     . SER B 2 285 ? 133.524 124.297 169.527 1.00 84.23  ? 267 SER D C     1 
ATOM   3024  O O     . SER B 2 285 ? 133.421 123.278 170.218 1.00 84.23  ? 267 SER D O     1 
ATOM   3025  C CB    . SER B 2 285 ? 131.446 124.318 168.143 1.00 84.23  ? 267 SER D CB    1 
ATOM   3026  O OG    . SER B 2 285 ? 130.726 123.257 168.745 1.00 84.23  ? 267 SER D OG    1 
ATOM   3027  N N     . GLU B 2 286 ? 134.702 124.731 169.059 1.00 87.70  ? 268 GLU D N     1 
ATOM   3028  C CA    . GLU B 2 286 ? 135.934 124.002 169.348 1.00 87.70  ? 268 GLU D CA    1 
ATOM   3029  C C     . GLU B 2 286 ? 136.259 123.988 170.837 1.00 87.70  ? 268 GLU D C     1 
ATOM   3030  O O     . GLU B 2 286 ? 136.896 123.043 171.319 1.00 87.70  ? 268 GLU D O     1 
ATOM   3031  C CB    . GLU B 2 286 ? 137.103 124.598 168.553 1.00 87.70  ? 268 GLU D CB    1 
ATOM   3032  C CG    . GLU B 2 286 ? 137.410 126.082 168.820 1.00 87.70  ? 268 GLU D CG    1 
ATOM   3033  C CD    . GLU B 2 286 ? 138.683 126.557 168.137 1.00 87.70  ? 268 GLU D CD    1 
ATOM   3034  O OE1   . GLU B 2 286 ? 139.628 125.754 167.990 1.00 87.70  ? 268 GLU D OE1   1 
ATOM   3035  O OE2   . GLU B 2 286 ? 138.739 127.743 167.749 1.00 87.70  ? 268 GLU D OE2   1 
ATOM   3036  N N     . VAL B 2 287 ? 135.843 125.020 171.578 1.00 81.39  ? 269 VAL D N     1 
ATOM   3037  C CA    . VAL B 2 287 ? 136.130 125.048 173.009 1.00 81.39  ? 269 VAL D CA    1 
ATOM   3038  C C     . VAL B 2 287 ? 135.363 123.942 173.726 1.00 81.39  ? 269 VAL D C     1 
ATOM   3039  O O     . VAL B 2 287 ? 135.877 123.344 174.675 1.00 81.39  ? 269 VAL D O     1 
ATOM   3040  C CB    . VAL B 2 287 ? 135.839 126.440 173.615 1.00 81.39  ? 269 VAL D CB    1 
ATOM   3041  C CG1   . VAL B 2 287 ? 136.539 127.535 172.815 1.00 81.39  ? 269 VAL D CG1   1 
ATOM   3042  C CG2   . VAL B 2 287 ? 134.345 126.717 173.715 1.00 81.39  ? 269 VAL D CG2   1 
ATOM   3043  N N     . ARG B 2 288 ? 134.146 123.626 173.272 1.00 81.76  ? 270 ARG D N     1 
ATOM   3044  C CA    . ARG B 2 288 ? 133.389 122.539 173.884 1.00 81.76  ? 270 ARG D CA    1 
ATOM   3045  C C     . ARG B 2 288 ? 134.041 121.192 173.605 1.00 81.76  ? 270 ARG D C     1 
ATOM   3046  O O     . ARG B 2 288 ? 134.075 120.320 174.481 1.00 81.76  ? 270 ARG D O     1 
ATOM   3047  C CB    . ARG B 2 288 ? 131.945 122.553 173.371 1.00 81.76  ? 270 ARG D CB    1 
ATOM   3048  C CG    . ARG B 2 288 ? 131.016 123.635 173.957 1.00 81.76  ? 270 ARG D CG    1 
ATOM   3049  C CD    . ARG B 2 288 ? 130.855 123.556 175.490 1.00 81.76  ? 270 ARG D CD    1 
ATOM   3050  N NE    . ARG B 2 288 ? 129.798 124.406 176.035 1.00 81.76  ? 270 ARG D NE    1 
ATOM   3051  C CZ    . ARG B 2 288 ? 128.500 124.324 175.758 1.00 81.76  ? 270 ARG D CZ    1 
ATOM   3052  N NH1   . ARG B 2 288 ? 127.994 123.333 175.037 1.00 81.76  ? 270 ARG D NH1   1 
ATOM   3053  N NH2   . ARG B 2 288 ? 127.676 125.242 176.255 1.00 81.76  ? 270 ARG D NH2   1 
ATOM   3054  N N     . GLU B 2 289 ? 134.569 121.003 172.393 1.00 88.38  ? 271 GLU D N     1 
ATOM   3055  C CA    . GLU B 2 289 ? 135.275 119.762 172.087 1.00 88.38  ? 271 GLU D CA    1 
ATOM   3056  C C     . GLU B 2 289 ? 136.551 119.644 172.910 1.00 88.38  ? 271 GLU D C     1 
ATOM   3057  O O     . GLU B 2 289 ? 136.885 118.554 173.393 1.00 88.38  ? 271 GLU D O     1 
ATOM   3058  C CB    . GLU B 2 289 ? 135.599 119.686 170.591 1.00 88.38  ? 271 GLU D CB    1 
ATOM   3059  C CG    . GLU B 2 289 ? 134.432 119.975 169.639 1.00 88.38  ? 271 GLU D CG    1 
ATOM   3060  C CD    . GLU B 2 289 ? 133.152 119.255 170.020 1.00 88.38  ? 271 GLU D CD    1 
ATOM   3061  O OE1   . GLU B 2 289 ? 133.228 118.067 170.399 1.00 88.38  ? 271 GLU D OE1   1 
ATOM   3062  O OE2   . GLU B 2 289 ? 132.072 119.876 169.941 1.00 88.38  ? 271 GLU D OE2   1 
ATOM   3063  N N     . GLN B 2 290 ? 137.274 120.756 173.076 1.00 89.03  ? 272 GLN D N     1 
ATOM   3064  C CA    . GLN B 2 290 ? 138.474 120.746 173.909 1.00 89.03  ? 272 GLN D CA    1 
ATOM   3065  C C     . GLN B 2 290 ? 138.111 120.422 175.353 1.00 89.03  ? 272 GLN D C     1 
ATOM   3066  O O     . GLN B 2 290 ? 138.822 119.661 176.019 1.00 89.03  ? 272 GLN D O     1 
ATOM   3067  C CB    . GLN B 2 290 ? 139.202 122.098 173.796 1.00 89.03  ? 272 GLN D CB    1 
ATOM   3068  C CG    . GLN B 2 290 ? 140.088 122.572 174.982 1.00 89.03  ? 272 GLN D CG    1 
ATOM   3069  C CD    . GLN B 2 290 ? 141.152 121.566 175.414 1.00 89.03  ? 272 GLN D CD    1 
ATOM   3070  O OE1   . GLN B 2 290 ? 141.388 120.564 174.741 1.00 89.03  ? 272 GLN D OE1   1 
ATOM   3071  N NE2   . GLN B 2 290 ? 141.791 121.833 176.547 1.00 89.03  ? 272 GLN D NE2   1 
ATOM   3072  N N     . ILE B 2 291 ? 137.005 120.988 175.847 1.00 86.02  ? 273 ILE D N     1 
ATOM   3073  C CA    . ILE B 2 291 ? 136.558 120.716 177.211 1.00 86.02  ? 273 ILE D CA    1 
ATOM   3074  C C     . ILE B 2 291 ? 136.215 119.242 177.366 1.00 86.02  ? 273 ILE D C     1 
ATOM   3075  O O     . ILE B 2 291 ? 136.617 118.600 178.342 1.00 86.02  ? 273 ILE D O     1 
ATOM   3076  C CB    . ILE B 2 291 ? 135.360 121.622 177.571 1.00 86.02  ? 273 ILE D CB    1 
ATOM   3077  C CG1   . ILE B 2 291 ? 135.812 123.074 177.755 1.00 86.02  ? 273 ILE D CG1   1 
ATOM   3078  C CG2   . ILE B 2 291 ? 134.655 121.148 178.856 1.00 86.02  ? 273 ILE D CG2   1 
ATOM   3079  C CD1   . ILE B 2 291 ? 134.720 124.095 177.487 1.00 86.02  ? 273 ILE D CD1   1 
ATOM   3080  N N     . ASP B 2 292 ? 135.493 118.681 176.391 1.00 90.95  ? 274 ASP D N     1 
ATOM   3081  C CA    . ASP B 2 292 ? 135.095 117.278 176.457 1.00 90.95  ? 274 ASP D CA    1 
ATOM   3082  C C     . ASP B 2 292 ? 136.308 116.357 176.460 1.00 90.95  ? 274 ASP D C     1 
ATOM   3083  O O     . ASP B 2 292 ? 136.434 115.489 177.331 1.00 90.95  ? 274 ASP D O     1 
ATOM   3084  C CB    . ASP B 2 292 ? 134.173 116.944 175.284 1.00 90.95  ? 274 ASP D CB    1 
ATOM   3085  C CG    . ASP B 2 292 ? 134.055 115.454 175.044 1.00 90.95  ? 274 ASP D CG    1 
ATOM   3086  O OD1   . ASP B 2 292 ? 133.333 114.780 175.808 1.00 90.95  ? 274 ASP D OD1   1 
ATOM   3087  O OD2   . ASP B 2 292 ? 134.687 114.954 174.090 1.00 90.95  ? 274 ASP D OD2   1 
ATOM   3088  N N     . THR B 2 293 ? 137.234 116.559 175.517 1.00 97.85  ? 275 THR D N     1 
ATOM   3089  C CA    . THR B 2 293 ? 138.402 115.685 175.435 1.00 97.85  ? 275 THR D CA    1 
ATOM   3090  C C     . THR B 2 293 ? 139.314 115.843 176.648 1.00 97.85  ? 275 THR D C     1 
ATOM   3091  O O     . THR B 2 293 ? 139.770 114.843 177.215 1.00 97.85  ? 275 THR D O     1 
ATOM   3092  C CB    . THR B 2 293 ? 139.184 115.954 174.147 1.00 97.85  ? 275 THR D CB    1 
ATOM   3093  O OG1   . THR B 2 293 ? 139.659 117.306 174.141 1.00 97.85  ? 275 THR D OG1   1 
ATOM   3094  C CG2   . THR B 2 293 ? 138.321 115.694 172.913 1.00 97.85  ? 275 THR D CG2   1 
ATOM   3095  N N     . LYS B 2 294 ? 139.584 117.083 177.071 1.00 98.64  ? 276 LYS D N     1 
ATOM   3096  C CA    . LYS B 2 294 ? 140.488 117.300 178.196 1.00 98.64  ? 276 LYS D CA    1 
ATOM   3097  C C     . LYS B 2 294 ? 139.895 116.774 179.497 1.00 98.64  ? 276 LYS D C     1 
ATOM   3098  O O     . LYS B 2 294 ? 140.602 116.143 180.292 1.00 98.64  ? 276 LYS D O     1 
ATOM   3099  C CB    . LYS B 2 294 ? 140.820 118.787 178.316 1.00 98.64  ? 276 LYS D CB    1 
ATOM   3100  C CG    . LYS B 2 294 ? 141.876 119.109 179.365 1.00 98.64  ? 276 LYS D CG    1 
ATOM   3101  C CD    . LYS B 2 294 ? 141.266 119.706 180.627 1.00 98.64  ? 276 LYS D CD    1 
ATOM   3102  C CE    . LYS B 2 294 ? 142.334 120.015 181.664 1.00 98.64  ? 276 LYS D CE    1 
ATOM   3103  N NZ    . LYS B 2 294 ? 141.780 120.720 182.853 1.00 98.64  ? 276 LYS D NZ    1 
ATOM   3104  N N     . VAL B 2 295 ? 138.602 117.014 179.735 1.00 98.11  ? 277 VAL D N     1 
ATOM   3105  C CA    . VAL B 2 295 ? 137.984 116.522 180.957 1.00 98.11  ? 277 VAL D CA    1 
ATOM   3106  C C     . VAL B 2 295 ? 137.857 115.006 180.920 1.00 98.11  ? 277 VAL D C     1 
ATOM   3107  O O     . VAL B 2 295 ? 137.975 114.355 181.959 1.00 98.11  ? 277 VAL D O     1 
ATOM   3108  C CB    . VAL B 2 295 ? 136.624 117.210 181.191 1.00 98.11  ? 277 VAL D CB    1 
ATOM   3109  C CG1   . VAL B 2 295 ? 135.881 116.561 182.365 1.00 98.11  ? 277 VAL D CG1   1 
ATOM   3110  C CG2   . VAL B 2 295 ? 136.834 118.698 181.471 1.00 98.11  ? 277 VAL D CG2   1 
ATOM   3111  N N     . ALA B 2 296 ? 137.623 114.412 179.745 1.00 103.40 ? 278 ALA D N     1 
ATOM   3112  C CA    . ALA B 2 296 ? 137.601 112.955 179.655 1.00 103.40 ? 278 ALA D CA    1 
ATOM   3113  C C     . ALA B 2 296 ? 138.971 112.365 179.963 1.00 103.40 ? 278 ALA D C     1 
ATOM   3114  O O     . ALA B 2 296 ? 139.077 111.358 180.674 1.00 103.40 ? 278 ALA D O     1 
ATOM   3115  C CB    . ALA B 2 296 ? 137.133 112.523 178.265 1.00 103.40 ? 278 ALA D CB    1 
ATOM   3116  N N     . GLU B 2 297 ? 140.033 112.988 179.448 1.00 109.19 ? 279 GLU D N     1 
ATOM   3117  C CA    . GLU B 2 297 ? 141.383 112.507 179.722 1.00 109.19 ? 279 GLU D CA    1 
ATOM   3118  C C     . GLU B 2 297 ? 141.738 112.656 181.197 1.00 109.19 ? 279 GLU D C     1 
ATOM   3119  O O     . GLU B 2 297 ? 142.331 111.748 181.791 1.00 109.19 ? 279 GLU D O     1 
ATOM   3120  C CB    . GLU B 2 297 ? 142.389 113.257 178.850 1.00 109.19 ? 279 GLU D CB    1 
ATOM   3121  C CG    . GLU B 2 297 ? 142.316 112.890 177.370 1.00 109.19 ? 279 GLU D CG    1 
ATOM   3122  C CD    . GLU B 2 297 ? 143.054 113.867 176.468 1.00 109.19 ? 279 GLU D CD    1 
ATOM   3123  O OE1   . GLU B 2 297 ? 143.702 114.802 176.985 1.00 109.19 ? 279 GLU D OE1   1 
ATOM   3124  O OE2   . GLU B 2 297 ? 142.982 113.699 175.233 1.00 109.19 ? 279 GLU D OE2   1 
ATOM   3125  N N     . TRP B 2 298 ? 141.382 113.790 181.806 1.00 111.13 ? 280 TRP D N     1 
ATOM   3126  C CA    . TRP B 2 298 ? 141.734 114.029 183.202 1.00 111.13 ? 280 TRP D CA    1 
ATOM   3127  C C     . TRP B 2 298 ? 140.821 113.271 184.165 1.00 111.13 ? 280 TRP D C     1 
ATOM   3128  O O     . TRP B 2 298 ? 141.215 113.031 185.311 1.00 111.13 ? 280 TRP D O     1 
ATOM   3129  C CB    . TRP B 2 298 ? 141.697 115.535 183.507 1.00 111.13 ? 280 TRP D CB    1 
ATOM   3130  C CG    . TRP B 2 298 ? 143.064 116.184 183.446 1.00 111.13 ? 280 TRP D CG    1 
ATOM   3131  C CD1   . TRP B 2 298 ? 143.901 116.213 182.366 1.00 111.13 ? 280 TRP D CD1   1 
ATOM   3132  C CD2   . TRP B 2 298 ? 143.737 116.905 184.489 1.00 111.13 ? 280 TRP D CD2   1 
ATOM   3133  N NE1   . TRP B 2 298 ? 145.051 116.897 182.673 1.00 111.13 ? 280 TRP D NE1   1 
ATOM   3134  C CE2   . TRP B 2 298 ? 144.977 117.331 183.970 1.00 111.13 ? 280 TRP D CE2   1 
ATOM   3135  C CE3   . TRP B 2 298 ? 143.416 117.227 185.809 1.00 111.13 ? 280 TRP D CE3   1 
ATOM   3136  C CZ2   . TRP B 2 298 ? 145.893 118.062 184.726 1.00 111.13 ? 280 TRP D CZ2   1 
ATOM   3137  C CZ3   . TRP B 2 298 ? 144.328 117.950 186.561 1.00 111.13 ? 280 TRP D CZ3   1 
ATOM   3138  C CH2   . TRP B 2 298 ? 145.550 118.360 186.016 1.00 111.13 ? 280 TRP D CH2   1 
ATOM   3139  N N     . ARG B 2 299 ? 139.616 112.892 183.724 1.00 108.74 ? 281 ARG D N     1 
ATOM   3140  C CA    . ARG B 2 299 ? 138.742 112.009 184.488 1.00 108.74 ? 281 ARG D CA    1 
ATOM   3141  C C     . ARG B 2 299 ? 139.224 110.567 184.396 1.00 108.74 ? 281 ARG D C     1 
ATOM   3142  O O     . ARG B 2 299 ? 139.082 109.800 185.355 1.00 108.74 ? 281 ARG D O     1 
ATOM   3143  C CB    . ARG B 2 299 ? 137.305 112.144 183.961 1.00 108.74 ? 281 ARG D CB    1 
ATOM   3144  C CG    . ARG B 2 299 ? 136.209 111.339 184.689 1.00 108.74 ? 281 ARG D CG    1 
ATOM   3145  C CD    . ARG B 2 299 ? 134.926 111.267 183.859 1.00 108.74 ? 281 ARG D CD    1 
ATOM   3146  N NE    . ARG B 2 299 ? 134.294 112.579 183.698 1.00 108.74 ? 281 ARG D NE    1 
ATOM   3147  C CZ    . ARG B 2 299 ? 133.735 113.072 182.593 1.00 108.74 ? 281 ARG D CZ    1 
ATOM   3148  N NH1   . ARG B 2 299 ? 133.661 112.381 181.462 1.00 108.74 ? 281 ARG D NH1   1 
ATOM   3149  N NH2   . ARG B 2 299 ? 133.216 114.296 182.626 1.00 108.74 ? 281 ARG D NH2   1 
ATOM   3150  N N     . GLU B 2 300 ? 139.777 110.182 183.242 1.00 117.93 ? 282 GLU D N     1 
ATOM   3151  C CA    . GLU B 2 300 ? 140.413 108.875 183.123 1.00 117.93 ? 282 GLU D CA    1 
ATOM   3152  C C     . GLU B 2 300 ? 141.600 108.768 184.072 1.00 117.93 ? 282 GLU D C     1 
ATOM   3153  O O     . GLU B 2 300 ? 141.832 107.715 184.677 1.00 117.93 ? 282 GLU D O     1 
ATOM   3154  C CB    . GLU B 2 300 ? 140.838 108.646 181.668 1.00 117.93 ? 282 GLU D CB    1 
ATOM   3155  C CG    . GLU B 2 300 ? 141.601 107.354 181.388 1.00 117.93 ? 282 GLU D CG    1 
ATOM   3156  C CD    . GLU B 2 300 ? 141.815 107.123 179.905 1.00 117.93 ? 282 GLU D CD    1 
ATOM   3157  O OE1   . GLU B 2 300 ? 140.827 107.180 179.143 1.00 117.93 ? 282 GLU D OE1   1 
ATOM   3158  O OE2   . GLU B 2 300 ? 142.973 106.889 179.499 1.00 117.93 ? 282 GLU D OE2   1 
ATOM   3159  N N     . GLU B 2 301 ? 142.359 109.854 184.217 1.00 118.81 ? 283 GLU D N     1 
ATOM   3160  C CA    . GLU B 2 301 ? 143.458 109.915 185.172 1.00 118.81 ? 283 GLU D CA    1 
ATOM   3161  C C     . GLU B 2 301 ? 142.997 110.074 186.619 1.00 118.81 ? 283 GLU D C     1 
ATOM   3162  O O     . GLU B 2 301 ? 143.829 109.965 187.526 1.00 118.81 ? 283 GLU D O     1 
ATOM   3163  C CB    . GLU B 2 301 ? 144.400 111.071 184.815 1.00 118.81 ? 283 GLU D CB    1 
ATOM   3164  C CG    . GLU B 2 301 ? 145.121 110.929 183.474 1.00 118.81 ? 283 GLU D CG    1 
ATOM   3165  C CD    . GLU B 2 301 ? 146.412 110.144 183.586 1.00 118.81 ? 283 GLU D CD    1 
ATOM   3166  O OE1   . GLU B 2 301 ? 146.447 109.161 184.355 1.00 118.81 ? 283 GLU D OE1   1 
ATOM   3167  O OE2   . GLU B 2 301 ? 147.393 110.512 182.906 1.00 118.81 ? 283 GLU D OE2   1 
ATOM   3168  N N     . GLY B 2 302 ? 141.709 110.327 186.865 1.00 117.64 ? 284 GLY D N     1 
ATOM   3169  C CA    . GLY B 2 302 ? 141.218 110.515 188.216 1.00 117.64 ? 284 GLY D CA    1 
ATOM   3170  C C     . GLY B 2 302 ? 141.776 111.756 188.880 1.00 117.64 ? 284 GLY D C     1 
ATOM   3171  O O     . GLY B 2 302 ? 142.212 111.700 190.035 1.00 117.64 ? 284 GLY D O     1 
ATOM   3172  N N     . LYS B 2 303 ? 141.767 112.883 188.153 1.00 114.50 ? 285 LYS D N     1 
ATOM   3173  C CA    . LYS B 2 303 ? 142.372 114.147 188.573 1.00 114.50 ? 285 LYS D CA    1 
ATOM   3174  C C     . LYS B 2 303 ? 141.408 115.325 188.529 1.00 114.50 ? 285 LYS D C     1 
ATOM   3175  O O     . LYS B 2 303 ? 141.501 116.209 189.385 1.00 114.50 ? 285 LYS D O     1 
ATOM   3176  C CB    . LYS B 2 303 ? 143.599 114.451 187.694 1.00 114.50 ? 285 LYS D CB    1 
ATOM   3177  C CG    . LYS B 2 303 ? 144.759 113.458 187.830 1.00 114.50 ? 285 LYS D CG    1 
ATOM   3178  C CD    . LYS B 2 303 ? 145.804 113.921 188.841 1.00 114.50 ? 285 LYS D CD    1 
ATOM   3179  C CE    . LYS B 2 303 ? 147.017 113.004 188.841 1.00 114.50 ? 285 LYS D CE    1 
ATOM   3180  N NZ    . LYS B 2 303 ? 148.130 113.552 189.664 1.00 114.50 ? 285 LYS D NZ    1 
ATOM   3181  N N     . ALA B 2 304 ? 140.499 115.371 187.554 1.00 108.48 ? 286 ALA D N     1 
ATOM   3182  C CA    . ALA B 2 304 ? 139.540 116.467 187.457 1.00 108.48 ? 286 ALA D CA    1 
ATOM   3183  C C     . ALA B 2 304 ? 138.305 116.001 186.701 1.00 108.48 ? 286 ALA D C     1 
ATOM   3184  O O     . ALA B 2 304 ? 138.354 115.051 185.916 1.00 108.48 ? 286 ALA D O     1 
ATOM   3185  C CB    . ALA B 2 304 ? 140.146 117.691 186.763 1.00 108.48 ? 286 ALA D CB    1 
ATOM   3186  N N     . GLU B 2 305 ? 137.195 116.695 186.956 1.00 98.99  ? 287 GLU D N     1 
ATOM   3187  C CA    . GLU B 2 305 ? 135.917 116.420 186.312 1.00 98.99  ? 287 GLU D CA    1 
ATOM   3188  C C     . GLU B 2 305 ? 135.179 117.735 186.110 1.00 98.99  ? 287 GLU D C     1 
ATOM   3189  O O     . GLU B 2 305 ? 135.491 118.750 186.740 1.00 98.99  ? 287 GLU D O     1 
ATOM   3190  C CB    . GLU B 2 305 ? 135.037 115.460 187.133 1.00 98.99  ? 287 GLU D CB    1 
ATOM   3191  C CG    . GLU B 2 305 ? 135.723 114.179 187.645 1.00 98.99  ? 287 GLU D CG    1 
ATOM   3192  C CD    . GLU B 2 305 ? 136.497 114.356 188.952 1.00 98.99  ? 287 GLU D CD    1 
ATOM   3193  O OE1   . GLU B 2 305 ? 136.166 115.257 189.752 1.00 98.99  ? 287 GLU D OE1   1 
ATOM   3194  O OE2   . GLU B 2 305 ? 137.454 113.585 189.173 1.00 98.99  ? 287 GLU D OE2   1 
ATOM   3195  N N     . ILE B 2 306 ? 134.191 117.705 185.220 1.00 82.71  ? 288 ILE D N     1 
ATOM   3196  C CA    . ILE B 2 306 ? 133.305 118.845 185.012 1.00 82.71  ? 288 ILE D CA    1 
ATOM   3197  C C     . ILE B 2 306 ? 132.276 118.888 186.134 1.00 82.71  ? 288 ILE D C     1 
ATOM   3198  O O     . ILE B 2 306 ? 131.890 117.850 186.685 1.00 82.71  ? 288 ILE D O     1 
ATOM   3199  C CB    . ILE B 2 306 ? 132.630 118.764 183.627 1.00 82.71  ? 288 ILE D CB    1 
ATOM   3200  C CG1   . ILE B 2 306 ? 131.994 120.109 183.254 1.00 82.71  ? 288 ILE D CG1   1 
ATOM   3201  C CG2   . ILE B 2 306 ? 131.582 117.645 183.587 1.00 82.71  ? 288 ILE D CG2   1 
ATOM   3202  C CD1   . ILE B 2 306 ? 131.458 120.157 181.844 1.00 82.71  ? 288 ILE D CD1   1 
ATOM   3203  N N     . VAL B 2 307 ? 131.842 120.105 186.476 1.00 70.12  ? 289 VAL D N     1 
ATOM   3204  C CA    . VAL B 2 307 ? 130.831 120.341 187.501 1.00 70.12  ? 289 VAL D CA    1 
ATOM   3205  C C     . VAL B 2 307 ? 129.807 121.326 186.942 1.00 70.12  ? 289 VAL D C     1 
ATOM   3206  O O     . VAL B 2 307 ? 130.183 122.360 186.374 1.00 70.12  ? 289 VAL D O     1 
ATOM   3207  C CB    . VAL B 2 307 ? 131.453 120.845 188.820 1.00 70.12  ? 289 VAL D CB    1 
ATOM   3208  C CG1   . VAL B 2 307 ? 131.732 122.353 188.863 1.00 70.12  ? 289 VAL D CG1   1 
ATOM   3209  C CG2   . VAL B 2 307 ? 130.571 120.449 189.998 1.00 70.12  ? 289 VAL D CG2   1 
ATOM   3210  N N     . PRO B 2 308 ? 128.501 121.003 186.941 1.00 61.79  ? 290 PRO D N     1 
ATOM   3211  C CA    . PRO B 2 308 ? 127.496 122.056 186.744 1.00 61.79  ? 290 PRO D CA    1 
ATOM   3212  C C     . PRO B 2 308 ? 127.312 122.896 187.997 1.00 61.79  ? 290 PRO D C     1 
ATOM   3213  O O     . PRO B 2 308 ? 127.312 122.380 189.117 1.00 61.79  ? 290 PRO D O     1 
ATOM   3214  C CB    . PRO B 2 308 ? 126.219 121.276 186.409 1.00 61.79  ? 290 PRO D CB    1 
ATOM   3215  C CG    . PRO B 2 308 ? 126.684 119.998 185.873 1.00 61.79  ? 290 PRO D CG    1 
ATOM   3216  C CD    . PRO B 2 308 ? 127.930 119.677 186.625 1.00 61.79  ? 290 PRO D CD    1 
ATOM   3217  N N     . GLY B 2 309 ? 127.140 124.196 187.794 1.00 54.63  ? 291 GLY D N     1 
ATOM   3218  C CA    . GLY B 2 309 ? 126.926 125.170 188.856 1.00 54.63  ? 291 GLY D CA    1 
ATOM   3219  C C     . GLY B 2 309 ? 125.472 125.565 188.986 1.00 54.63  ? 291 GLY D C     1 
ATOM   3220  O O     . GLY B 2 309 ? 124.568 124.740 188.815 1.00 54.63  ? 291 GLY D O     1 
ATOM   3221  N N     . VAL B 2 310 ? 125.248 126.840 189.305 1.00 49.93  ? 292 VAL D N     1 
ATOM   3222  C CA    . VAL B 2 310 ? 123.914 127.413 189.462 1.00 49.93  ? 292 VAL D CA    1 
ATOM   3223  C C     . VAL B 2 310 ? 123.912 128.781 188.795 1.00 49.93  ? 292 VAL D C     1 
ATOM   3224  O O     . VAL B 2 310 ? 124.854 129.562 188.975 1.00 49.93  ? 292 VAL D O     1 
ATOM   3225  C CB    . VAL B 2 310 ? 123.512 127.525 190.948 1.00 49.93  ? 292 VAL D CB    1 
ATOM   3226  C CG1   . VAL B 2 310 ? 122.254 128.395 191.124 1.00 49.93  ? 292 VAL D CG1   1 
ATOM   3227  C CG2   . VAL B 2 310 ? 123.315 126.135 191.548 1.00 49.93  ? 292 VAL D CG2   1 
ATOM   3228  N N     . LEU B 2 311 ? 122.865 129.060 188.020 1.00 47.94  ? 293 LEU D N     1 
ATOM   3229  C CA    . LEU B 2 311 ? 122.621 130.369 187.425 1.00 47.94  ? 293 LEU D CA    1 
ATOM   3230  C C     . LEU B 2 311 ? 121.358 130.938 188.050 1.00 47.94  ? 293 LEU D C     1 
ATOM   3231  O O     . LEU B 2 311 ? 120.297 130.308 187.972 1.00 47.94  ? 293 LEU D O     1 
ATOM   3232  C CB    . LEU B 2 311 ? 122.458 130.258 185.905 1.00 47.94  ? 293 LEU D CB    1 
ATOM   3233  C CG    . LEU B 2 311 ? 121.797 131.395 185.104 1.00 47.94  ? 293 LEU D CG    1 
ATOM   3234  C CD1   . LEU B 2 311 ? 122.453 132.746 185.354 1.00 47.94  ? 293 LEU D CD1   1 
ATOM   3235  C CD2   . LEU B 2 311 ? 121.808 131.072 183.625 1.00 47.94  ? 293 LEU D CD2   1 
ATOM   3236  N N     . PHE B 2 312 ? 121.469 132.133 188.632 1.00 49.00  ? 294 PHE D N     1 
ATOM   3237  C CA    . PHE B 2 312 ? 120.358 132.832 189.265 1.00 49.00  ? 294 PHE D CA    1 
ATOM   3238  C C     . PHE B 2 312 ? 119.968 134.047 188.436 1.00 49.00  ? 294 PHE D C     1 
ATOM   3239  O O     . PHE B 2 312 ? 120.834 134.846 188.054 1.00 49.00  ? 294 PHE D O     1 
ATOM   3240  C CB    . PHE B 2 312 ? 120.714 133.258 190.688 1.00 49.00  ? 294 PHE D CB    1 
ATOM   3241  C CG    . PHE B 2 312 ? 119.578 133.904 191.422 1.00 49.00  ? 294 PHE D CG    1 
ATOM   3242  C CD1   . PHE B 2 312 ? 118.497 133.159 191.849 1.00 49.00  ? 294 PHE D CD1   1 
ATOM   3243  C CD2   . PHE B 2 312 ? 119.595 135.255 191.693 1.00 49.00  ? 294 PHE D CD2   1 
ATOM   3244  C CE1   . PHE B 2 312 ? 117.457 133.749 192.528 1.00 49.00  ? 294 PHE D CE1   1 
ATOM   3245  C CE2   . PHE B 2 312 ? 118.562 135.847 192.370 1.00 49.00  ? 294 PHE D CE2   1 
ATOM   3246  C CZ    . PHE B 2 312 ? 117.488 135.094 192.788 1.00 49.00  ? 294 PHE D CZ    1 
ATOM   3247  N N     . ILE B 2 313 ? 118.665 134.176 188.165 1.00 50.08  ? 295 ILE D N     1 
ATOM   3248  C CA    . ILE B 2 313 ? 118.118 135.253 187.334 1.00 50.08  ? 295 ILE D CA    1 
ATOM   3249  C C     . ILE B 2 313 ? 117.073 135.977 188.175 1.00 50.08  ? 295 ILE D C     1 
ATOM   3250  O O     . ILE B 2 313 ? 115.934 135.511 188.303 1.00 50.08  ? 295 ILE D O     1 
ATOM   3251  C CB    . ILE B 2 313 ? 117.527 134.736 186.013 1.00 50.08  ? 295 ILE D CB    1 
ATOM   3252  C CG1   . ILE B 2 313 ? 118.539 133.815 185.311 1.00 50.08  ? 295 ILE D CG1   1 
ATOM   3253  C CG2   . ILE B 2 313 ? 117.144 135.905 185.054 1.00 50.08  ? 295 ILE D CG2   1 
ATOM   3254  C CD1   . ILE B 2 313 ? 118.205 133.453 183.867 1.00 50.08  ? 295 ILE D CD1   1 
ATOM   3255  N N     . ASP B 2 314 ? 117.450 137.132 188.724 1.00 54.08  ? 296 ASP D N     1 
ATOM   3256  C CA    . ASP B 2 314 ? 116.481 138.024 189.355 1.00 54.08  ? 296 ASP D CA    1 
ATOM   3257  C C     . ASP B 2 314 ? 115.655 138.752 188.303 1.00 54.08  ? 296 ASP D C     1 
ATOM   3258  O O     . ASP B 2 314 ? 116.134 139.070 187.212 1.00 54.08  ? 296 ASP D O     1 
ATOM   3259  C CB    . ASP B 2 314 ? 117.175 139.069 190.252 1.00 54.08  ? 296 ASP D CB    1 
ATOM   3260  C CG    . ASP B 2 314 ? 116.865 138.915 191.754 1.00 54.08  ? 296 ASP D CG    1 
ATOM   3261  O OD1   . ASP B 2 314 ? 116.327 137.890 192.222 1.00 54.08  ? 296 ASP D OD1   1 
ATOM   3262  O OD2   . ASP B 2 314 ? 117.176 139.873 192.494 1.00 54.08  ? 296 ASP D OD2   1 
ATOM   3263  N N     . GLU B 2 315 ? 114.395 139.016 188.654 1.00 57.54  ? 297 GLU D N     1 
ATOM   3264  C CA    . GLU B 2 315 ? 113.492 139.816 187.829 1.00 57.54  ? 297 GLU D CA    1 
ATOM   3265  C C     . GLU B 2 315 ? 113.223 139.123 186.491 1.00 57.54  ? 297 GLU D C     1 
ATOM   3266  O O     . GLU B 2 315 ? 113.340 139.716 185.417 1.00 57.54  ? 297 GLU D O     1 
ATOM   3267  C CB    . GLU B 2 315 ? 114.060 141.225 187.633 1.00 57.54  ? 297 GLU D CB    1 
ATOM   3268  C CG    . GLU B 2 315 ? 113.024 142.285 187.285 1.00 57.54  ? 297 GLU D CG    1 
ATOM   3269  C CD    . GLU B 2 315 ? 113.635 143.587 186.777 1.00 57.54  ? 297 GLU D CD    1 
ATOM   3270  O OE1   . GLU B 2 315 ? 114.876 143.680 186.660 1.00 57.54  ? 297 GLU D OE1   1 
ATOM   3271  O OE2   . GLU B 2 315 ? 112.866 144.530 186.499 1.00 57.54  ? 297 GLU D OE2   1 
ATOM   3272  N N     . VAL B 2 316 ? 112.848 137.842 186.572 1.00 48.90  ? 298 VAL D N     1 
ATOM   3273  C CA    . VAL B 2 316 ? 112.645 137.032 185.373 1.00 48.90  ? 298 VAL D CA    1 
ATOM   3274  C C     . VAL B 2 316 ? 111.467 137.539 184.547 1.00 48.90  ? 298 VAL D C     1 
ATOM   3275  O O     . VAL B 2 316 ? 111.425 137.328 183.330 1.00 48.90  ? 298 VAL D O     1 
ATOM   3276  C CB    . VAL B 2 316 ? 112.468 135.552 185.765 1.00 48.90  ? 298 VAL D CB    1 
ATOM   3277  C CG1   . VAL B 2 316 ? 111.090 135.295 186.359 1.00 48.90  ? 298 VAL D CG1   1 
ATOM   3278  C CG2   . VAL B 2 316 ? 112.720 134.638 184.570 1.00 48.90  ? 298 VAL D CG2   1 
ATOM   3279  N N     . HIS B 2 317 ? 110.491 138.199 185.180 1.00 52.97  ? 299 HIS D N     1 
ATOM   3280  C CA    . HIS B 2 317 ? 109.370 138.774 184.437 1.00 52.97  ? 299 HIS D CA    1 
ATOM   3281  C C     . HIS B 2 317 ? 109.805 139.839 183.433 1.00 52.97  ? 299 HIS D C     1 
ATOM   3282  O O     . HIS B 2 317 ? 109.080 140.087 182.464 1.00 52.97  ? 299 HIS D O     1 
ATOM   3283  C CB    . HIS B 2 317 ? 108.336 139.372 185.400 1.00 52.97  ? 299 HIS D CB    1 
ATOM   3284  C CG    . HIS B 2 317 ? 108.881 140.441 186.297 1.00 52.97  ? 299 HIS D CG    1 
ATOM   3285  N ND1   . HIS B 2 317 ? 109.505 140.159 187.493 1.00 52.97  ? 299 HIS D ND1   1 
ATOM   3286  C CD2   . HIS B 2 317 ? 108.898 141.789 186.173 1.00 52.97  ? 299 HIS D CD2   1 
ATOM   3287  C CE1   . HIS B 2 317 ? 109.881 141.286 188.068 1.00 52.97  ? 299 HIS D CE1   1 
ATOM   3288  N NE2   . HIS B 2 317 ? 109.526 142.290 187.287 1.00 52.97  ? 299 HIS D NE2   1 
ATOM   3289  N N     . MET B 2 318 ? 110.962 140.473 183.636 1.00 60.07  ? 300 MET D N     1 
ATOM   3290  C CA    . MET B 2 318 ? 111.497 141.417 182.660 1.00 60.07  ? 300 MET D CA    1 
ATOM   3291  C C     . MET B 2 318 ? 112.107 140.742 181.436 1.00 60.07  ? 300 MET D C     1 
ATOM   3292  O O     . MET B 2 318 ? 112.421 141.442 180.467 1.00 60.07  ? 300 MET D O     1 
ATOM   3293  C CB    . MET B 2 318 ? 112.557 142.320 183.305 1.00 60.07  ? 300 MET D CB    1 
ATOM   3294  C CG    . MET B 2 318 ? 112.348 143.795 183.028 1.00 60.07  ? 300 MET D CG    1 
ATOM   3295  S SD    . MET B 2 318 ? 110.990 144.482 183.992 1.00 60.07  ? 300 MET D SD    1 
ATOM   3296  C CE    . MET B 2 318 ? 110.497 145.845 182.947 1.00 60.07  ? 300 MET D CE    1 
ATOM   3297  N N     . LEU B 2 319 ? 112.294 139.423 181.446 1.00 55.25  ? 301 LEU D N     1 
ATOM   3298  C CA    . LEU B 2 319 ? 112.885 138.749 180.299 1.00 55.25  ? 301 LEU D CA    1 
ATOM   3299  C C     . LEU B 2 319 ? 111.932 138.781 179.110 1.00 55.25  ? 301 LEU D C     1 
ATOM   3300  O O     . LEU B 2 319 ? 110.709 138.710 179.263 1.00 55.25  ? 301 LEU D O     1 
ATOM   3301  C CB    . LEU B 2 319 ? 113.215 137.294 180.639 1.00 55.25  ? 301 LEU D CB    1 
ATOM   3302  C CG    . LEU B 2 319 ? 114.380 136.963 181.579 1.00 55.25  ? 301 LEU D CG    1 
ATOM   3303  C CD1   . LEU B 2 319 ? 114.523 135.462 181.712 1.00 55.25  ? 301 LEU D CD1   1 
ATOM   3304  C CD2   . LEU B 2 319 ? 115.686 137.559 181.115 1.00 55.25  ? 301 LEU D CD2   1 
ATOM   3305  N N     . ASP B 2 320 ? 112.509 138.882 177.915 1.00 59.13  ? 302 ASP D N     1 
ATOM   3306  C CA    . ASP B 2 320 ? 111.746 138.867 176.677 1.00 59.13  ? 302 ASP D CA    1 
ATOM   3307  C C     . ASP B 2 320 ? 111.454 137.425 176.259 1.00 59.13  ? 302 ASP D C     1 
ATOM   3308  O O     . ASP B 2 320 ? 112.050 136.473 176.767 1.00 59.13  ? 302 ASP D O     1 
ATOM   3309  C CB    . ASP B 2 320 ? 112.514 139.607 175.579 1.00 59.13  ? 302 ASP D CB    1 
ATOM   3310  C CG    . ASP B 2 320 ? 111.615 140.114 174.457 1.00 59.13  ? 302 ASP D CG    1 
ATOM   3311  O OD1   . ASP B 2 320 ? 110.416 139.765 174.418 1.00 59.13  ? 302 ASP D OD1   1 
ATOM   3312  O OD2   . ASP B 2 320 ? 112.121 140.873 173.603 1.00 59.13  ? 302 ASP D OD2   1 
ATOM   3313  N N     . ILE B 2 321 ? 110.513 137.270 175.323 1.00 54.21  ? 303 ILE D N     1 
ATOM   3314  C CA    . ILE B 2 321 ? 110.135 135.934 174.862 1.00 54.21  ? 303 ILE D CA    1 
ATOM   3315  C C     . ILE B 2 321 ? 111.304 135.260 174.146 1.00 54.21  ? 303 ILE D C     1 
ATOM   3316  O O     . ILE B 2 321 ? 111.467 134.033 174.228 1.00 54.21  ? 303 ILE D O     1 
ATOM   3317  C CB    . ILE B 2 321 ? 108.860 136.016 173.985 1.00 54.21  ? 303 ILE D CB    1 
ATOM   3318  C CG1   . ILE B 2 321 ? 108.279 134.627 173.661 1.00 54.21  ? 303 ILE D CG1   1 
ATOM   3319  C CG2   . ILE B 2 321 ? 109.090 136.803 172.684 1.00 54.21  ? 303 ILE D CG2   1 
ATOM   3320  C CD1   . ILE B 2 321 ? 107.686 133.902 174.855 1.00 54.21  ? 303 ILE D CD1   1 
ATOM   3321  N N     . GLU B 2 322 ? 112.132 136.037 173.441 1.00 58.73  ? 304 GLU D N     1 
ATOM   3322  C CA    . GLU B 2 322 ? 113.344 135.478 172.851 1.00 58.73  ? 304 GLU D CA    1 
ATOM   3323  C C     . GLU B 2 322 ? 114.286 134.956 173.928 1.00 58.73  ? 304 GLU D C     1 
ATOM   3324  O O     . GLU B 2 322 ? 114.945 133.927 173.740 1.00 58.73  ? 304 GLU D O     1 
ATOM   3325  C CB    . GLU B 2 322 ? 114.053 136.524 171.988 1.00 58.73  ? 304 GLU D CB    1 
ATOM   3326  C CG    . GLU B 2 322 ? 113.266 136.986 170.771 1.00 58.73  ? 304 GLU D CG    1 
ATOM   3327  C CD    . GLU B 2 322 ? 112.496 138.267 171.020 1.00 58.73  ? 304 GLU D CD    1 
ATOM   3328  O OE1   . GLU B 2 322 ? 111.675 138.295 171.955 1.00 58.73  ? 304 GLU D OE1   1 
ATOM   3329  O OE2   . GLU B 2 322 ? 112.710 139.247 170.277 1.00 58.73  ? 304 GLU D OE2   1 
ATOM   3330  N N     . CYS B 2 323 ? 114.355 135.645 175.070 1.00 57.40  ? 305 CYS D N     1 
ATOM   3331  C CA    . CYS B 2 323 ? 115.200 135.172 176.161 1.00 57.40  ? 305 CYS D CA    1 
ATOM   3332  C C     . CYS B 2 323 ? 114.668 133.871 176.750 1.00 57.40  ? 305 CYS D C     1 
ATOM   3333  O O     . CYS B 2 323 ? 115.450 133.000 177.137 1.00 57.40  ? 305 CYS D O     1 
ATOM   3334  C CB    . CYS B 2 323 ? 115.318 136.246 177.241 1.00 57.40  ? 305 CYS D CB    1 
ATOM   3335  S SG    . CYS B 2 323 ? 116.033 137.797 176.655 1.00 57.40  ? 305 CYS D SG    1 
ATOM   3336  N N     . PHE B 2 324 ? 113.345 133.711 176.818 1.00 52.08  ? 306 PHE D N     1 
ATOM   3337  C CA    . PHE B 2 324 ? 112.783 132.452 177.303 1.00 52.08  ? 306 PHE D CA    1 
ATOM   3338  C C     . PHE B 2 324 ? 113.048 131.313 176.326 1.00 52.08  ? 306 PHE D C     1 
ATOM   3339  O O     . PHE B 2 324 ? 113.335 130.179 176.742 1.00 52.08  ? 306 PHE D O     1 
ATOM   3340  C CB    . PHE B 2 324 ? 111.283 132.607 177.547 1.00 52.08  ? 306 PHE D CB    1 
ATOM   3341  C CG    . PHE B 2 324 ? 110.944 133.418 178.765 1.00 52.08  ? 306 PHE D CG    1 
ATOM   3342  C CD1   . PHE B 2 324 ? 111.159 132.912 180.034 1.00 52.08  ? 306 PHE D CD1   1 
ATOM   3343  C CD2   . PHE B 2 324 ? 110.405 134.685 178.639 1.00 52.08  ? 306 PHE D CD2   1 
ATOM   3344  C CE1   . PHE B 2 324 ? 110.845 133.655 181.151 1.00 52.08  ? 306 PHE D CE1   1 
ATOM   3345  C CE2   . PHE B 2 324 ? 110.088 135.431 179.754 1.00 52.08  ? 306 PHE D CE2   1 
ATOM   3346  C CZ    . PHE B 2 324 ? 110.307 134.915 181.010 1.00 52.08  ? 306 PHE D CZ    1 
ATOM   3347  N N     . SER B 2 325 ? 112.943 131.590 175.023 1.00 52.91  ? 307 SER D N     1 
ATOM   3348  C CA    . SER B 2 325 ? 113.282 130.576 174.028 1.00 52.91  ? 307 SER D CA    1 
ATOM   3349  C C     . SER B 2 325 ? 114.752 130.189 174.126 1.00 52.91  ? 307 SER D C     1 
ATOM   3350  O O     . SER B 2 325 ? 115.101 129.004 174.033 1.00 52.91  ? 307 SER D O     1 
ATOM   3351  C CB    . SER B 2 325 ? 112.954 131.089 172.628 1.00 52.91  ? 307 SER D CB    1 
ATOM   3352  O OG    . SER B 2 325 ? 111.576 131.394 172.513 1.00 52.91  ? 307 SER D OG    1 
ATOM   3353  N N     . PHE B 2 326 ? 115.625 131.175 174.340 1.00 56.57  ? 308 PHE D N     1 
ATOM   3354  C CA    . PHE B 2 326 ? 117.037 130.879 174.546 1.00 56.57  ? 308 PHE D CA    1 
ATOM   3355  C C     . PHE B 2 326 ? 117.253 130.083 175.826 1.00 56.57  ? 308 PHE D C     1 
ATOM   3356  O O     . PHE B 2 326 ? 118.158 129.247 175.894 1.00 56.57  ? 308 PHE D O     1 
ATOM   3357  C CB    . PHE B 2 326 ? 117.851 132.173 174.580 1.00 56.57  ? 308 PHE D CB    1 
ATOM   3358  C CG    . PHE B 2 326 ? 119.326 131.949 174.746 1.00 56.57  ? 308 PHE D CG    1 
ATOM   3359  C CD1   . PHE B 2 326 ? 120.111 131.628 173.655 1.00 56.57  ? 308 PHE D CD1   1 
ATOM   3360  C CD2   . PHE B 2 326 ? 119.927 132.057 175.989 1.00 56.57  ? 308 PHE D CD2   1 
ATOM   3361  C CE1   . PHE B 2 326 ? 121.463 131.415 173.799 1.00 56.57  ? 308 PHE D CE1   1 
ATOM   3362  C CE2   . PHE B 2 326 ? 121.277 131.840 176.138 1.00 56.57  ? 308 PHE D CE2   1 
ATOM   3363  C CZ    . PHE B 2 326 ? 122.045 131.521 175.042 1.00 56.57  ? 308 PHE D CZ    1 
ATOM   3364  N N     . LEU B 2 327 ? 116.457 130.355 176.864 1.00 51.57  ? 309 LEU D N     1 
ATOM   3365  C CA    . LEU B 2 327 ? 116.578 129.601 178.108 1.00 51.57  ? 309 LEU D CA    1 
ATOM   3366  C C     . LEU B 2 327 ? 116.242 128.134 177.891 1.00 51.57  ? 309 LEU D C     1 
ATOM   3367  O O     . LEU B 2 327 ? 116.959 127.249 178.373 1.00 51.57  ? 309 LEU D O     1 
ATOM   3368  C CB    . LEU B 2 327 ? 115.670 130.196 179.185 1.00 51.57  ? 309 LEU D CB    1 
ATOM   3369  C CG    . LEU B 2 327 ? 116.255 131.370 179.970 1.00 51.57  ? 309 LEU D CG    1 
ATOM   3370  C CD1   . LEU B 2 327 ? 115.152 132.296 180.447 1.00 51.57  ? 309 LEU D CD1   1 
ATOM   3371  C CD2   . LEU B 2 327 ? 117.078 130.879 181.143 1.00 51.57  ? 309 LEU D CD2   1 
ATOM   3372  N N     . ASN B 2 328 ? 115.161 127.859 177.157 1.00 51.86  ? 310 ASN D N     1 
ATOM   3373  C CA    . ASN B 2 328 ? 114.823 126.475 176.830 1.00 51.86  ? 310 ASN D CA    1 
ATOM   3374  C C     . ASN B 2 328 ? 115.914 125.826 175.983 1.00 51.86  ? 310 ASN D C     1 
ATOM   3375  O O     . ASN B 2 328 ? 116.295 124.670 176.223 1.00 51.86  ? 310 ASN D O     1 
ATOM   3376  C CB    . ASN B 2 328 ? 113.482 126.418 176.102 1.00 51.86  ? 310 ASN D CB    1 
ATOM   3377  C CG    . ASN B 2 328 ? 112.305 126.573 177.040 1.00 51.86  ? 310 ASN D CG    1 
ATOM   3378  O OD1   . ASN B 2 328 ? 111.942 125.640 177.756 1.00 51.86  ? 310 ASN D OD1   1 
ATOM   3379  N ND2   . ASN B 2 328 ? 111.699 127.755 177.043 1.00 51.86  ? 310 ASN D ND2   1 
ATOM   3380  N N     . ARG B 2 329 ? 116.441 126.566 175.003 1.00 54.77  ? 311 ARG D N     1 
ATOM   3381  C CA    . ARG B 2 329 ? 117.483 126.028 174.131 1.00 54.77  ? 311 ARG D CA    1 
ATOM   3382  C C     . ARG B 2 329 ? 118.754 125.706 174.911 1.00 54.77  ? 311 ARG D C     1 
ATOM   3383  O O     . ARG B 2 329 ? 119.392 124.674 174.673 1.00 54.77  ? 311 ARG D O     1 
ATOM   3384  C CB    . ARG B 2 329 ? 117.782 127.027 173.012 1.00 54.77  ? 311 ARG D CB    1 
ATOM   3385  C CG    . ARG B 2 329 ? 118.523 126.434 171.803 1.00 54.77  ? 311 ARG D CG    1 
ATOM   3386  C CD    . ARG B 2 329 ? 118.213 127.141 170.477 1.00 54.77  ? 311 ARG D CD    1 
ATOM   3387  N NE    . ARG B 2 329 ? 116.790 127.102 170.120 1.00 54.77  ? 311 ARG D NE    1 
ATOM   3388  C CZ    . ARG B 2 329 ? 115.970 128.138 169.946 1.00 54.77  ? 311 ARG D CZ    1 
ATOM   3389  N NH1   . ARG B 2 329 ? 116.362 129.396 170.106 1.00 54.77  ? 311 ARG D NH1   1 
ATOM   3390  N NH2   . ARG B 2 329 ? 114.707 127.905 169.603 1.00 54.77  ? 311 ARG D NH2   1 
ATOM   3391  N N     . ALA B 2 330 ? 119.134 126.576 175.847 1.00 56.07  ? 312 ALA D N     1 
ATOM   3392  C CA    . ALA B 2 330 ? 120.342 126.348 176.631 1.00 56.07  ? 312 ALA D CA    1 
ATOM   3393  C C     . ALA B 2 330 ? 120.144 125.221 177.633 1.00 56.07  ? 312 ALA D C     1 
ATOM   3394  O O     . ALA B 2 330 ? 121.047 124.401 177.836 1.00 56.07  ? 312 ALA D O     1 
ATOM   3395  C CB    . ALA B 2 330 ? 120.753 127.634 177.344 1.00 56.07  ? 312 ALA D CB    1 
ATOM   3396  N N     . LEU B 2 331 ? 118.969 125.154 178.265 1.00 51.39  ? 313 LEU D N     1 
ATOM   3397  C CA    . LEU B 2 331 ? 118.684 124.061 179.186 1.00 51.39  ? 313 LEU D CA    1 
ATOM   3398  C C     . LEU B 2 331 ? 118.595 122.715 178.479 1.00 51.39  ? 313 LEU D C     1 
ATOM   3399  O O     . LEU B 2 331 ? 118.769 121.680 179.131 1.00 51.39  ? 313 LEU D O     1 
ATOM   3400  C CB    . LEU B 2 331 ? 117.377 124.332 179.937 1.00 51.39  ? 313 LEU D CB    1 
ATOM   3401  C CG    . LEU B 2 331 ? 117.355 125.434 181.004 1.00 51.39  ? 313 LEU D CG    1 
ATOM   3402  C CD1   . LEU B 2 331 ? 115.942 125.627 181.534 1.00 51.39  ? 313 LEU D CD1   1 
ATOM   3403  C CD2   . LEU B 2 331 ? 118.306 125.134 182.155 1.00 51.39  ? 313 LEU D CD2   1 
ATOM   3404  N N     . GLU B 2 332 ? 118.318 122.699 177.170 1.00 58.06  ? 314 GLU D N     1 
ATOM   3405  C CA    . GLU B 2 332 ? 118.332 121.436 176.439 1.00 58.06  ? 314 GLU D CA    1 
ATOM   3406  C C     . GLU B 2 332 ? 119.724 120.807 176.408 1.00 58.06  ? 314 GLU D C     1 
ATOM   3407  O O     . GLU B 2 332 ? 119.841 119.580 176.320 1.00 58.06  ? 314 GLU D O     1 
ATOM   3408  C CB    . GLU B 2 332 ? 117.809 121.654 175.014 1.00 58.06  ? 314 GLU D CB    1 
ATOM   3409  C CG    . GLU B 2 332 ? 117.701 120.397 174.132 1.00 58.06  ? 314 GLU D CG    1 
ATOM   3410  C CD    . GLU B 2 332 ? 116.814 119.316 174.725 1.00 58.06  ? 314 GLU D CD    1 
ATOM   3411  O OE1   . GLU B 2 332 ? 115.936 119.650 175.547 1.00 58.06  ? 314 GLU D OE1   1 
ATOM   3412  O OE2   . GLU B 2 332 ? 117.000 118.132 174.372 1.00 58.06  ? 314 GLU D OE2   1 
ATOM   3413  N N     . ASN B 2 333 ? 120.782 121.616 176.469 1.00 63.73  ? 315 ASN D N     1 
ATOM   3414  C CA    . ASN B 2 333 ? 122.139 121.086 176.427 1.00 63.73  ? 315 ASN D CA    1 
ATOM   3415  C C     . ASN B 2 333 ? 122.443 120.254 177.669 1.00 63.73  ? 315 ASN D C     1 
ATOM   3416  O O     . ASN B 2 333 ? 121.974 120.543 178.773 1.00 63.73  ? 315 ASN D O     1 
ATOM   3417  C CB    . ASN B 2 333 ? 123.158 122.220 176.311 1.00 63.73  ? 315 ASN D CB    1 
ATOM   3418  C CG    . ASN B 2 333 ? 123.115 122.913 174.963 1.00 63.73  ? 315 ASN D CG    1 
ATOM   3419  O OD1   . ASN B 2 333 ? 122.857 122.286 173.935 1.00 63.73  ? 315 ASN D OD1   1 
ATOM   3420  N ND2   . ASN B 2 333 ? 123.375 124.214 174.960 1.00 63.73  ? 315 ASN D ND2   1 
ATOM   3421  N N     . GLU B 2 334 ? 123.242 119.202 177.470 1.00 71.04  ? 316 GLU D N     1 
ATOM   3422  C CA    . GLU B 2 334 ? 123.604 118.315 178.573 1.00 71.04  ? 316 GLU D CA    1 
ATOM   3423  C C     . GLU B 2 334 ? 124.485 119.007 179.610 1.00 71.04  ? 316 GLU D C     1 
ATOM   3424  O O     . GLU B 2 334 ? 124.471 118.616 180.783 1.00 71.04  ? 316 GLU D O     1 
ATOM   3425  C CB    . GLU B 2 334 ? 124.289 117.054 178.023 1.00 71.04  ? 316 GLU D CB    1 
ATOM   3426  C CG    . GLU B 2 334 ? 125.798 117.141 177.695 1.00 71.04  ? 316 GLU D CG    1 
ATOM   3427  C CD    . GLU B 2 334 ? 126.152 118.259 176.731 1.00 71.04  ? 316 GLU D CD    1 
ATOM   3428  O OE1   . GLU B 2 334 ? 125.241 118.766 176.044 1.00 71.04  ? 316 GLU D OE1   1 
ATOM   3429  O OE2   . GLU B 2 334 ? 127.341 118.630 176.660 1.00 71.04  ? 316 GLU D OE2   1 
ATOM   3430  N N     . MET B 2 335 ? 125.249 120.025 179.211 1.00 71.36  ? 317 MET D N     1 
ATOM   3431  C CA    . MET B 2 335 ? 126.171 120.716 180.110 1.00 71.36  ? 317 MET D CA    1 
ATOM   3432  C C     . MET B 2 335 ? 125.505 121.828 180.918 1.00 71.36  ? 317 MET D C     1 
ATOM   3433  O O     . MET B 2 335 ? 126.199 122.522 181.669 1.00 71.36  ? 317 MET D O     1 
ATOM   3434  C CB    . MET B 2 335 ? 127.355 121.298 179.314 1.00 71.36  ? 317 MET D CB    1 
ATOM   3435  C CG    . MET B 2 335 ? 128.676 120.600 179.580 1.00 71.36  ? 317 MET D CG    1 
ATOM   3436  S SD    . MET B 2 335 ? 130.047 121.355 178.686 1.00 71.36  ? 317 MET D SD    1 
ATOM   3437  C CE    . MET B 2 335 ? 130.539 120.007 177.615 1.00 71.36  ? 317 MET D CE    1 
ATOM   3438  N N     . SER B 2 336 ? 124.187 121.997 180.811 1.00 58.35  ? 318 SER D N     1 
ATOM   3439  C CA    . SER B 2 336 ? 123.532 123.168 181.368 1.00 58.35  ? 318 SER D CA    1 
ATOM   3440  C C     . SER B 2 336 ? 123.544 123.125 182.901 1.00 58.35  ? 318 SER D C     1 
ATOM   3441  O O     . SER B 2 336 ? 123.518 122.042 183.492 1.00 58.35  ? 318 SER D O     1 
ATOM   3442  C CB    . SER B 2 336 ? 122.095 123.246 180.863 1.00 58.35  ? 318 SER D CB    1 
ATOM   3443  O OG    . SER B 2 336 ? 121.388 124.323 181.450 1.00 58.35  ? 318 SER D OG    1 
ATOM   3444  N N     . PRO B 2 337 ? 123.579 124.307 183.584 1.00 54.64  ? 319 PRO D N     1 
ATOM   3445  C CA    . PRO B 2 337 ? 123.544 124.303 185.052 1.00 54.64  ? 319 PRO D CA    1 
ATOM   3446  C C     . PRO B 2 337 ? 122.122 124.334 185.584 1.00 54.64  ? 319 PRO D C     1 
ATOM   3447  O O     . PRO B 2 337 ? 121.167 124.359 184.802 1.00 54.64  ? 319 PRO D O     1 
ATOM   3448  C CB    . PRO B 2 337 ? 124.304 125.583 185.402 1.00 54.64  ? 319 PRO D CB    1 
ATOM   3449  C CG    . PRO B 2 337 ? 123.856 126.516 184.353 1.00 54.64  ? 319 PRO D CG    1 
ATOM   3450  C CD    . PRO B 2 337 ? 123.704 125.694 183.092 1.00 54.64  ? 319 PRO D CD    1 
ATOM   3451  N N     . ILE B 2 338 ? 121.967 124.340 186.904 1.00 48.12  ? 320 ILE D N     1 
ATOM   3452  C CA    . ILE B 2 338 ? 120.651 124.464 187.519 1.00 48.12  ? 320 ILE D CA    1 
ATOM   3453  C C     . ILE B 2 338 ? 120.226 125.924 187.439 1.00 48.12  ? 320 ILE D C     1 
ATOM   3454  O O     . ILE B 2 338 ? 120.963 126.824 187.866 1.00 48.12  ? 320 ILE D O     1 
ATOM   3455  C CB    . ILE B 2 338 ? 120.674 123.956 188.975 1.00 48.12  ? 320 ILE D CB    1 
ATOM   3456  C CG1   . ILE B 2 338 ? 120.883 122.422 189.020 1.00 48.12  ? 320 ILE D CG1   1 
ATOM   3457  C CG2   . ILE B 2 338 ? 119.378 124.381 189.728 1.00 48.12  ? 320 ILE D CG2   1 
ATOM   3458  C CD1   . ILE B 2 338 ? 122.333 121.954 188.905 1.00 48.12  ? 320 ILE D CD1   1 
ATOM   3459  N N     . LEU B 2 339 ? 119.034 126.158 186.898 1.00 43.74  ? 321 LEU D N     1 
ATOM   3460  C CA    . LEU B 2 339 ? 118.471 127.492 186.736 1.00 43.74  ? 321 LEU D CA    1 
ATOM   3461  C C     . LEU B 2 339 ? 117.565 127.807 187.918 1.00 43.74  ? 321 LEU D C     1 
ATOM   3462  O O     . LEU B 2 339 ? 116.713 126.989 188.287 1.00 43.74  ? 321 LEU D O     1 
ATOM   3463  C CB    . LEU B 2 339 ? 117.694 127.585 185.420 1.00 43.74  ? 321 LEU D CB    1 
ATOM   3464  C CG    . LEU B 2 339 ? 116.967 128.888 185.061 1.00 43.74  ? 321 LEU D CG    1 
ATOM   3465  C CD1   . LEU B 2 339 ? 117.958 129.991 184.784 1.00 43.74  ? 321 LEU D CD1   1 
ATOM   3466  C CD2   . LEU B 2 339 ? 116.064 128.685 183.859 1.00 43.74  ? 321 LEU D CD2   1 
ATOM   3467  N N     . VAL B 2 340 ? 117.751 128.996 188.497 1.00 44.51  ? 322 VAL D N     1 
ATOM   3468  C CA    . VAL B 2 340 ? 116.915 129.501 189.587 1.00 44.51  ? 322 VAL D CA    1 
ATOM   3469  C C     . VAL B 2 340 ? 116.462 130.897 189.165 1.00 44.51  ? 322 VAL D C     1 
ATOM   3470  O O     . VAL B 2 340 ? 117.164 131.891 189.373 1.00 44.51  ? 322 VAL D O     1 
ATOM   3471  C CB    . VAL B 2 340 ? 117.652 129.529 190.930 1.00 44.51  ? 322 VAL D CB    1 
ATOM   3472  C CG1   . VAL B 2 340 ? 116.689 129.861 192.079 1.00 44.51  ? 322 VAL D CG1   1 
ATOM   3473  C CG2   . VAL B 2 340 ? 118.350 128.193 191.166 1.00 44.51  ? 322 VAL D CG2   1 
ATOM   3474  N N     . VAL B 2 341 ? 115.291 130.975 188.547 1.00 44.83  ? 323 VAL D N     1 
ATOM   3475  C CA    . VAL B 2 341 ? 114.688 132.272 188.253 1.00 44.83  ? 323 VAL D CA    1 
ATOM   3476  C C     . VAL B 2 341 ? 113.995 132.802 189.508 1.00 44.83  ? 323 VAL D C     1 
ATOM   3477  O O     . VAL B 2 341 ? 113.770 132.080 190.484 1.00 44.83  ? 323 VAL D O     1 
ATOM   3478  C CB    . VAL B 2 341 ? 113.725 132.210 187.043 1.00 44.83  ? 323 VAL D CB    1 
ATOM   3479  C CG1   . VAL B 2 341 ? 114.518 132.038 185.756 1.00 44.83  ? 323 VAL D CG1   1 
ATOM   3480  C CG2   . VAL B 2 341 ? 112.687 131.094 187.142 1.00 44.83  ? 323 VAL D CG2   1 
ATOM   3481  N N     . ALA B 2 342 ? 113.699 134.100 189.501 1.00 45.77  ? 324 ALA D N     1 
ATOM   3482  C CA    . ALA B 2 342 ? 113.049 134.741 190.635 1.00 45.77  ? 324 ALA D CA    1 
ATOM   3483  C C     . ALA B 2 342 ? 112.159 135.863 190.130 1.00 45.77  ? 324 ALA D C     1 
ATOM   3484  O O     . ALA B 2 342 ? 112.542 136.603 189.221 1.00 45.77  ? 324 ALA D O     1 
ATOM   3485  C CB    . ALA B 2 342 ? 114.074 135.286 191.633 1.00 45.77  ? 324 ALA D CB    1 
ATOM   3486  N N     . THR B 2 343 ? 110.972 135.976 190.728 1.00 48.37  ? 325 THR D N     1 
ATOM   3487  C CA    . THR B 2 343 ? 109.974 136.956 190.322 1.00 48.37  ? 325 THR D CA    1 
ATOM   3488  C C     . THR B 2 343 ? 109.311 137.555 191.550 1.00 48.37  ? 325 THR D C     1 
ATOM   3489  O O     . THR B 2 343 ? 109.232 136.922 192.605 1.00 48.37  ? 325 THR D O     1 
ATOM   3490  C CB    . THR B 2 343 ? 108.898 136.338 189.413 1.00 48.37  ? 325 THR D CB    1 
ATOM   3491  O OG1   . THR B 2 343 ? 108.080 137.379 188.866 1.00 48.37  ? 325 THR D OG1   1 
ATOM   3492  C CG2   . THR B 2 343 ? 108.010 135.362 190.184 1.00 48.37  ? 325 THR D CG2   1 
ATOM   3493  N N     . ASN B 2 344 ? 108.837 138.788 191.392 1.00 50.30  ? 326 ASN D N     1 
ATOM   3494  C CA    . ASN B 2 344 ? 108.053 139.507 192.389 1.00 50.30  ? 326 ASN D CA    1 
ATOM   3495  C C     . ASN B 2 344 ? 106.837 140.149 191.735 1.00 50.30  ? 326 ASN D C     1 
ATOM   3496  O O     . ASN B 2 344 ? 106.449 141.275 192.062 1.00 50.30  ? 326 ASN D O     1 
ATOM   3497  C CB    . ASN B 2 344 ? 108.920 140.536 193.116 1.00 50.30  ? 326 ASN D CB    1 
ATOM   3498  C CG    . ASN B 2 344 ? 109.708 141.431 192.166 1.00 50.30  ? 326 ASN D CG    1 
ATOM   3499  O OD1   . ASN B 2 344 ? 109.244 141.784 191.082 1.00 50.30  ? 326 ASN D OD1   1 
ATOM   3500  N ND2   . ASN B 2 344 ? 110.916 141.798 192.575 1.00 50.30  ? 326 ASN D ND2   1 
ATOM   3501  N N     . ARG B 2 345 ? 106.228 139.429 190.791 1.00 54.19  ? 327 ARG D N     1 
ATOM   3502  C CA    . ARG B 2 345 ? 105.104 139.908 189.999 1.00 54.19  ? 327 ARG D CA    1 
ATOM   3503  C C     . ARG B 2 345 ? 104.094 138.781 189.859 1.00 54.19  ? 327 ARG D C     1 
ATOM   3504  O O     . ARG B 2 345 ? 104.471 137.614 189.725 1.00 54.19  ? 327 ARG D O     1 
ATOM   3505  C CB    . ARG B 2 345 ? 105.572 140.384 188.613 1.00 54.19  ? 327 ARG D CB    1 
ATOM   3506  C CG    . ARG B 2 345 ? 104.530 141.146 187.782 1.00 54.19  ? 327 ARG D CG    1 
ATOM   3507  C CD    . ARG B 2 345 ? 104.192 142.531 188.335 1.00 54.19  ? 327 ARG D CD    1 
ATOM   3508  N NE    . ARG B 2 345 ? 105.358 143.407 188.410 1.00 54.19  ? 327 ARG D NE    1 
ATOM   3509  C CZ    . ARG B 2 345 ? 105.408 144.575 189.043 1.00 54.19  ? 327 ARG D CZ    1 
ATOM   3510  N NH1   . ARG B 2 345 ? 104.362 145.070 189.692 1.00 54.19  ? 327 ARG D NH1   1 
ATOM   3511  N NH2   . ARG B 2 345 ? 106.542 145.269 189.027 1.00 54.19  ? 327 ARG D NH2   1 
ATOM   3512  N N     . GLY B 2 346 ? 102.812 139.137 189.895 1.00 52.19  ? 328 GLY D N     1 
ATOM   3513  C CA    . GLY B 2 346 ? 101.749 138.167 189.722 1.00 52.19  ? 328 GLY D CA    1 
ATOM   3514  C C     . GLY B 2 346 ? 101.481 137.875 188.262 1.00 52.19  ? 328 GLY D C     1 
ATOM   3515  O O     . GLY B 2 346 ? 102.414 137.831 187.454 1.00 52.19  ? 328 GLY D O     1 
ATOM   3516  N N     . VAL B 2 347 ? 100.213 137.667 187.908 1.00 51.08  ? 329 VAL D N     1 
ATOM   3517  C CA    . VAL B 2 347 ? 99.856  137.460 186.510 1.00 51.08  ? 329 VAL D CA    1 
ATOM   3518  C C     . VAL B 2 347 ? 100.091 138.752 185.740 1.00 51.08  ? 329 VAL D C     1 
ATOM   3519  O O     . VAL B 2 347 ? 99.675  139.836 186.168 1.00 51.08  ? 329 VAL D O     1 
ATOM   3520  C CB    . VAL B 2 347 ? 98.401  136.970 186.383 1.00 51.08  ? 329 VAL D CB    1 
ATOM   3521  C CG1   . VAL B 2 347 ? 97.376  138.010 186.891 1.00 51.08  ? 329 VAL D CG1   1 
ATOM   3522  C CG2   . VAL B 2 347 ? 98.081  136.562 184.938 1.00 51.08  ? 329 VAL D CG2   1 
ATOM   3523  N N     . THR B 2 348 ? 100.778 138.645 184.607 1.00 52.74  ? 330 THR D N     1 
ATOM   3524  C CA    . THR B 2 348 ? 101.099 139.809 183.794 1.00 52.74  ? 330 THR D CA    1 
ATOM   3525  C C     . THR B 2 348 ? 101.395 139.340 182.378 1.00 52.74  ? 330 THR D C     1 
ATOM   3526  O O     . THR B 2 348 ? 101.586 138.149 182.123 1.00 52.74  ? 330 THR D O     1 
ATOM   3527  C CB    . THR B 2 348 ? 102.284 140.593 184.372 1.00 52.74  ? 330 THR D CB    1 
ATOM   3528  O OG1   . THR B 2 348 ? 102.403 141.851 183.699 1.00 52.74  ? 330 THR D OG1   1 
ATOM   3529  C CG2   . THR B 2 348 ? 103.591 139.819 184.214 1.00 52.74  ? 330 THR D CG2   1 
ATOM   3530  N N     . THR B 2 349 ? 101.421 140.298 181.456 1.00 53.71  ? 331 THR D N     1 
ATOM   3531  C CA    . THR B 2 349 ? 101.742 139.992 180.071 1.00 53.71  ? 331 THR D CA    1 
ATOM   3532  C C     . THR B 2 349 ? 103.183 139.518 179.952 1.00 53.71  ? 331 THR D C     1 
ATOM   3533  O O     . THR B 2 349 ? 104.093 140.085 180.562 1.00 53.71  ? 331 THR D O     1 
ATOM   3534  C CB    . THR B 2 349 ? 101.532 141.222 179.189 1.00 53.71  ? 331 THR D CB    1 
ATOM   3535  O OG1   . THR B 2 349 ? 102.280 142.324 179.716 1.00 53.71  ? 331 THR D OG1   1 
ATOM   3536  C CG2   . THR B 2 349 ? 100.058 141.594 179.124 1.00 53.71  ? 331 THR D CG2   1 
ATOM   3537  N N     . ILE B 2 350 ? 103.389 138.460 179.169 1.00 53.80  ? 332 ILE D N     1 
ATOM   3538  C CA    . ILE B 2 350 ? 104.742 138.089 178.779 1.00 53.80  ? 332 ILE D CA    1 
ATOM   3539  C C     . ILE B 2 350 ? 105.300 139.213 177.922 1.00 53.80  ? 332 ILE D C     1 
ATOM   3540  O O     . ILE B 2 350 ? 104.684 139.618 176.927 1.00 53.80  ? 332 ILE D O     1 
ATOM   3541  C CB    . ILE B 2 350 ? 104.757 136.743 178.035 1.00 53.80  ? 332 ILE D CB    1 
ATOM   3542  C CG1   . ILE B 2 350 ? 104.340 135.584 178.955 1.00 53.80  ? 332 ILE D CG1   1 
ATOM   3543  C CG2   . ILE B 2 350 ? 106.147 136.467 177.461 1.00 53.80  ? 332 ILE D CG2   1 
ATOM   3544  C CD1   . ILE B 2 350 ? 103.793 134.379 178.214 1.00 53.80  ? 332 ILE D CD1   1 
ATOM   3545  N N     . ARG B 2 351 ? 106.458 139.736 178.312 1.00 60.84  ? 333 ARG D N     1 
ATOM   3546  C CA    . ARG B 2 351 ? 106.932 140.989 177.739 1.00 60.84  ? 333 ARG D CA    1 
ATOM   3547  C C     . ARG B 2 351 ? 107.373 140.771 176.298 1.00 60.84  ? 333 ARG D C     1 
ATOM   3548  O O     . ARG B 2 351 ? 108.133 139.844 176.002 1.00 60.84  ? 333 ARG D O     1 
ATOM   3549  C CB    . ARG B 2 351 ? 108.078 141.566 178.577 1.00 60.84  ? 333 ARG D CB    1 
ATOM   3550  C CG    . ARG B 2 351 ? 107.988 143.079 178.807 1.00 60.84  ? 333 ARG D CG    1 
ATOM   3551  C CD    . ARG B 2 351 ? 108.888 143.536 179.945 1.00 60.84  ? 333 ARG D CD    1 
ATOM   3552  N NE    . ARG B 2 351 ? 110.301 143.366 179.626 1.00 60.84  ? 333 ARG D NE    1 
ATOM   3553  C CZ    . ARG B 2 351 ? 111.020 144.168 178.848 1.00 60.84  ? 333 ARG D CZ    1 
ATOM   3554  N NH1   . ARG B 2 351 ? 110.493 145.228 178.249 1.00 60.84  ? 333 ARG D NH1   1 
ATOM   3555  N NH2   . ARG B 2 351 ? 112.308 143.900 178.662 1.00 60.84  ? 333 ARG D NH2   1 
ATOM   3556  N N     . GLY B 2 352 ? 106.888 141.637 175.404 1.00 62.69  ? 334 GLY D N     1 
ATOM   3557  C CA    . GLY B 2 352 ? 107.048 141.475 173.975 1.00 62.69  ? 334 GLY D CA    1 
ATOM   3558  C C     . GLY B 2 352 ? 105.908 140.763 173.270 1.00 62.69  ? 334 GLY D C     1 
ATOM   3559  O O     . GLY B 2 352 ? 105.918 140.702 172.034 1.00 62.69  ? 334 GLY D O     1 
ATOM   3560  N N     . THR B 2 353 ? 104.938 140.214 174.009 1.00 58.50  ? 335 THR D N     1 
ATOM   3561  C CA    . THR B 2 353 ? 103.751 139.566 173.458 1.00 58.50  ? 335 THR D CA    1 
ATOM   3562  C C     . THR B 2 353 ? 102.520 140.087 174.191 1.00 58.50  ? 335 THR D C     1 
ATOM   3563  O O     . THR B 2 353 ? 102.620 140.913 175.104 1.00 58.50  ? 335 THR D O     1 
ATOM   3564  C CB    . THR B 2 353 ? 103.830 138.036 173.574 1.00 58.50  ? 335 THR D CB    1 
ATOM   3565  O OG1   . THR B 2 353 ? 103.426 137.633 174.889 1.00 58.50  ? 335 THR D OG1   1 
ATOM   3566  C CG2   . THR B 2 353 ? 105.244 137.528 173.297 1.00 58.50  ? 335 THR D CG2   1 
ATOM   3567  N N     . ASN B 2 354 ? 101.350 139.590 173.779 1.00 58.03  ? 336 ASN D N     1 
ATOM   3568  C CA    . ASN B 2 354 ? 100.061 139.978 174.343 1.00 58.03  ? 336 ASN D CA    1 
ATOM   3569  C C     . ASN B 2 354 ? 99.482  138.957 175.318 1.00 58.03  ? 336 ASN D C     1 
ATOM   3570  O O     . ASN B 2 354 ? 98.503  139.274 176.003 1.00 58.03  ? 336 ASN D O     1 
ATOM   3571  C CB    . ASN B 2 354 ? 99.046  140.211 173.217 1.00 58.03  ? 336 ASN D CB    1 
ATOM   3572  C CG    . ASN B 2 354 ? 99.585  141.106 172.118 1.00 58.03  ? 336 ASN D CG    1 
ATOM   3573  O OD1   . ASN B 2 354 ? 99.490  140.776 170.936 1.00 58.03  ? 336 ASN D OD1   1 
ATOM   3574  N ND2   . ASN B 2 354 ? 100.144 142.250 172.500 1.00 58.03  ? 336 ASN D ND2   1 
ATOM   3575  N N     . GLN B 2 355 ? 100.044 137.752 175.400 1.00 54.10  ? 337 GLN D N     1 
ATOM   3576  C CA    . GLN B 2 355 ? 99.490  136.715 176.259 1.00 54.10  ? 337 GLN D CA    1 
ATOM   3577  C C     . GLN B 2 355 ? 99.805  137.016 177.720 1.00 54.10  ? 337 GLN D C     1 
ATOM   3578  O O     . GLN B 2 355 ? 100.944 137.348 178.063 1.00 54.10  ? 337 GLN D O     1 
ATOM   3579  C CB    . GLN B 2 355 ? 100.054 135.350 175.863 1.00 54.10  ? 337 GLN D CB    1 
ATOM   3580  C CG    . GLN B 2 355 ? 99.339  134.147 176.475 1.00 54.10  ? 337 GLN D CG    1 
ATOM   3581  C CD    . GLN B 2 355 ? 100.160 132.875 176.368 1.00 54.10  ? 337 GLN D CD    1 
ATOM   3582  O OE1   . GLN B 2 355 ? 100.536 132.462 175.272 1.00 54.10  ? 337 GLN D OE1   1 
ATOM   3583  N NE2   . GLN B 2 355 ? 100.443 132.249 177.505 1.00 54.10  ? 337 GLN D NE2   1 
ATOM   3584  N N     . LYS B 2 356 ? 98.790  136.894 178.574 1.00 52.24  ? 338 LYS D N     1 
ATOM   3585  C CA    . LYS B 2 356 ? 98.936  137.011 180.019 1.00 52.24  ? 338 LYS D CA    1 
ATOM   3586  C C     . LYS B 2 356 ? 99.100  135.621 180.615 1.00 52.24  ? 338 LYS D C     1 
ATOM   3587  O O     . LYS B 2 356 ? 98.259  134.746 180.383 1.00 52.24  ? 338 LYS D O     1 
ATOM   3588  C CB    . LYS B 2 356 ? 97.722  137.708 180.633 1.00 52.24  ? 338 LYS D CB    1 
ATOM   3589  C CG    . LYS B 2 356 ? 97.652  139.203 180.341 1.00 52.24  ? 338 LYS D CG    1 
ATOM   3590  C CD    . LYS B 2 356 ? 96.562  139.909 181.147 1.00 52.24  ? 338 LYS D CD    1 
ATOM   3591  C CE    . LYS B 2 356 ? 95.156  139.487 180.728 1.00 52.24  ? 338 LYS D CE    1 
ATOM   3592  N NZ    . LYS B 2 356 ? 94.106  140.249 181.456 1.00 52.24  ? 338 LYS D NZ    1 
ATOM   3593  N N     . SER B 2 357 ? 100.176 135.429 181.372 1.00 50.62  ? 339 SER D N     1 
ATOM   3594  C CA    . SER B 2 357 ? 100.543 134.159 181.982 1.00 50.62  ? 339 SER D CA    1 
ATOM   3595  C C     . SER B 2 357 ? 100.974 134.407 183.418 1.00 50.62  ? 339 SER D C     1 
ATOM   3596  O O     . SER B 2 357 ? 101.243 135.554 183.797 1.00 50.62  ? 339 SER D O     1 
ATOM   3597  C CB    . SER B 2 357 ? 101.676 133.474 181.208 1.00 50.62  ? 339 SER D CB    1 
ATOM   3598  O OG    . SER B 2 357 ? 101.190 132.866 180.025 1.00 50.62  ? 339 SER D OG    1 
ATOM   3599  N N     . PRO B 2 358 ? 101.034 133.362 184.256 1.00 47.14  ? 340 PRO D N     1 
ATOM   3600  C CA    . PRO B 2 358 ? 101.530 133.555 185.627 1.00 47.14  ? 340 PRO D CA    1 
ATOM   3601  C C     . PRO B 2 358 ? 102.986 134.002 185.653 1.00 47.14  ? 340 PRO D C     1 
ATOM   3602  O O     . PRO B 2 358 ? 103.843 133.426 184.982 1.00 47.14  ? 340 PRO D O     1 
ATOM   3603  C CB    . PRO B 2 358 ? 101.362 132.171 186.264 1.00 47.14  ? 340 PRO D CB    1 
ATOM   3604  C CG    . PRO B 2 358 ? 100.335 131.506 185.468 1.00 47.14  ? 340 PRO D CG    1 
ATOM   3605  C CD    . PRO B 2 358 ? 100.528 131.985 184.076 1.00 47.14  ? 340 PRO D CD    1 
ATOM   3606  N N     . HIS B 2 359 ? 103.256 135.051 186.427 1.00 46.36  ? 341 HIS D N     1 
ATOM   3607  C CA    . HIS B 2 359 ? 104.591 135.600 186.654 1.00 46.36  ? 341 HIS D CA    1 
ATOM   3608  C C     . HIS B 2 359 ? 105.241 136.180 185.398 1.00 46.36  ? 341 HIS D C     1 
ATOM   3609  O O     . HIS B 2 359 ? 106.442 136.473 185.418 1.00 46.36  ? 341 HIS D O     1 
ATOM   3610  C CB    . HIS B 2 359 ? 105.535 134.552 187.262 1.00 46.36  ? 341 HIS D CB    1 
ATOM   3611  C CG    . HIS B 2 359 ? 104.968 133.838 188.449 1.00 46.36  ? 341 HIS D CG    1 
ATOM   3612  N ND1   . HIS B 2 359 ? 104.459 134.501 189.544 1.00 46.36  ? 341 HIS D ND1   1 
ATOM   3613  C CD2   . HIS B 2 359 ? 104.845 132.517 188.719 1.00 46.36  ? 341 HIS D CD2   1 
ATOM   3614  C CE1   . HIS B 2 359 ? 104.039 133.620 190.433 1.00 46.36  ? 341 HIS D CE1   1 
ATOM   3615  N NE2   . HIS B 2 359 ? 104.262 132.409 189.957 1.00 46.36  ? 341 HIS D NE2   1 
ATOM   3616  N N     . GLY B 2 360 ? 104.493 136.379 184.317 1.00 48.71  ? 342 GLY D N     1 
ATOM   3617  C CA    . GLY B 2 360 ? 105.094 136.854 183.080 1.00 48.71  ? 342 GLY D CA    1 
ATOM   3618  C C     . GLY B 2 360 ? 106.109 135.897 182.494 1.00 48.71  ? 342 GLY D C     1 
ATOM   3619  O O     . GLY B 2 360 ? 107.167 136.333 182.023 1.00 48.71  ? 342 GLY D O     1 
ATOM   3620  N N     . ILE B 2 361 ? 105.804 134.600 182.514 1.00 46.01  ? 343 ILE D N     1 
ATOM   3621  C CA    . ILE B 2 361 ? 106.686 133.526 182.048 1.00 46.01  ? 343 ILE D CA    1 
ATOM   3622  C C     . ILE B 2 361 ? 105.859 132.753 181.022 1.00 46.01  ? 343 ILE D C     1 
ATOM   3623  O O     . ILE B 2 361 ? 104.628 132.721 181.155 1.00 46.01  ? 343 ILE D O     1 
ATOM   3624  C CB    . ILE B 2 361 ? 107.169 132.639 183.218 1.00 46.01  ? 343 ILE D CB    1 
ATOM   3625  C CG1   . ILE B 2 361 ? 107.915 133.495 184.270 1.00 46.01  ? 343 ILE D CG1   1 
ATOM   3626  C CG2   . ILE B 2 361 ? 108.075 131.473 182.708 1.00 46.01  ? 343 ILE D CG2   1 
ATOM   3627  C CD1   . ILE B 2 361 ? 108.389 132.758 185.517 1.00 46.01  ? 343 ILE D CD1   1 
ATOM   3628  N N     . PRO B 2 362 ? 106.444 132.129 179.993 1.00 49.20  ? 344 PRO D N     1 
ATOM   3629  C CA    . PRO B 2 362 ? 105.634 131.276 179.119 1.00 49.20  ? 344 PRO D CA    1 
ATOM   3630  C C     . PRO B 2 362 ? 105.132 130.055 179.867 1.00 49.20  ? 344 PRO D C     1 
ATOM   3631  O O     . PRO B 2 362 ? 105.685 129.651 180.891 1.00 49.20  ? 344 PRO D O     1 
ATOM   3632  C CB    . PRO B 2 362 ? 106.599 130.881 177.996 1.00 49.20  ? 344 PRO D CB    1 
ATOM   3633  C CG    . PRO B 2 362 ? 107.654 131.896 178.028 1.00 49.20  ? 344 PRO D CG    1 
ATOM   3634  C CD    . PRO B 2 362 ? 107.818 132.236 179.467 1.00 49.20  ? 344 PRO D CD    1 
ATOM   3635  N N     . ILE B 2 363 ? 104.044 129.483 179.346 1.00 46.83  ? 345 ILE D N     1 
ATOM   3636  C CA    . ILE B 2 363 ? 103.450 128.304 179.972 1.00 46.83  ? 345 ILE D CA    1 
ATOM   3637  C C     . ILE B 2 363 ? 104.433 127.141 179.934 1.00 46.83  ? 345 ILE D C     1 
ATOM   3638  O O     . ILE B 2 363 ? 104.715 126.521 180.966 1.00 46.83  ? 345 ILE D O     1 
ATOM   3639  C CB    . ILE B 2 363 ? 102.119 127.935 179.285 1.00 46.83  ? 345 ILE D CB    1 
ATOM   3640  C CG1   . ILE B 2 363 ? 101.075 129.066 179.401 1.00 46.83  ? 345 ILE D CG1   1 
ATOM   3641  C CG2   . ILE B 2 363 ? 101.572 126.616 179.840 1.00 46.83  ? 345 ILE D CG2   1 
ATOM   3642  C CD1   . ILE B 2 363 ? 100.564 129.380 180.815 1.00 46.83  ? 345 ILE D CD1   1 
ATOM   3643  N N     . ASP B 2 364 ? 105.030 126.897 178.757 1.00 46.64  ? 346 ASP D N     1 
ATOM   3644  C CA    . ASP B 2 364 ? 105.852 125.705 178.520 1.00 46.64  ? 346 ASP D CA    1 
ATOM   3645  C C     . ASP B 2 364 ? 107.053 125.625 179.455 1.00 46.64  ? 346 ASP D C     1 
ATOM   3646  O O     . ASP B 2 364 ? 107.523 124.523 179.761 1.00 46.64  ? 346 ASP D O     1 
ATOM   3647  C CB    . ASP B 2 364 ? 106.347 125.664 177.070 1.00 46.64  ? 346 ASP D CB    1 
ATOM   3648  C CG    . ASP B 2 364 ? 107.058 126.941 176.649 1.00 46.64  ? 346 ASP D CG    1 
ATOM   3649  O OD1   . ASP B 2 364 ? 108.286 127.039 176.857 1.00 46.64  ? 346 ASP D OD1   1 
ATOM   3650  O OD2   . ASP B 2 364 ? 106.384 127.845 176.111 1.00 46.64  ? 346 ASP D OD2   1 
ATOM   3651  N N     . LEU B 2 365 ? 107.565 126.771 179.910 1.00 45.60  ? 347 LEU D N     1 
ATOM   3652  C CA    . LEU B 2 365 ? 108.523 126.761 181.009 1.00 45.60  ? 347 LEU D CA    1 
ATOM   3653  C C     . LEU B 2 365 ? 107.829 126.475 182.334 1.00 45.60  ? 347 LEU D C     1 
ATOM   3654  O O     . LEU B 2 365 ? 108.361 125.739 183.171 1.00 45.60  ? 347 LEU D O     1 
ATOM   3655  C CB    . LEU B 2 365 ? 109.267 128.097 181.072 1.00 45.60  ? 347 LEU D CB    1 
ATOM   3656  C CG    . LEU B 2 365 ? 110.612 128.104 181.824 1.00 45.60  ? 347 LEU D CG    1 
ATOM   3657  C CD1   . LEU B 2 365 ? 111.721 127.506 180.913 1.00 45.60  ? 347 LEU D CD1   1 
ATOM   3658  C CD2   . LEU B 2 365 ? 110.964 129.530 182.388 1.00 45.60  ? 347 LEU D CD2   1 
ATOM   3659  N N     . LEU B 2 366 ? 106.628 127.025 182.533 1.00 45.58  ? 348 LEU D N     1 
ATOM   3660  C CA    . LEU B 2 366 ? 105.969 126.931 183.831 1.00 45.58  ? 348 LEU D CA    1 
ATOM   3661  C C     . LEU B 2 366 ? 105.509 125.519 184.171 1.00 45.58  ? 348 LEU D C     1 
ATOM   3662  O O     . LEU B 2 366 ? 105.347 125.220 185.359 1.00 45.58  ? 348 LEU D O     1 
ATOM   3663  C CB    . LEU B 2 366 ? 104.767 127.879 183.890 1.00 45.58  ? 348 LEU D CB    1 
ATOM   3664  C CG    . LEU B 2 366 ? 104.992 129.374 184.134 1.00 45.58  ? 348 LEU D CG    1 
ATOM   3665  C CD1   . LEU B 2 366 ? 103.656 130.090 184.102 1.00 45.58  ? 348 LEU D CD1   1 
ATOM   3666  C CD2   . LEU B 2 366 ? 105.690 129.648 185.460 1.00 45.58  ? 348 LEU D CD2   1 
ATOM   3667  N N     . ASP B 2 367 ? 105.301 124.636 183.183 1.00 43.36  ? 349 ASP D N     1 
ATOM   3668  C CA    . ASP B 2 367 ? 104.956 123.260 183.559 1.00 43.36  ? 349 ASP D CA    1 
ATOM   3669  C C     . ASP B 2 367 ? 106.123 122.487 184.169 1.00 43.36  ? 349 ASP D C     1 
ATOM   3670  O O     . ASP B 2 367 ? 105.885 121.393 184.689 1.00 43.36  ? 349 ASP D O     1 
ATOM   3671  C CB    . ASP B 2 367 ? 104.425 122.395 182.402 1.00 43.36  ? 349 ASP D CB    1 
ATOM   3672  C CG    . ASP B 2 367 ? 103.526 123.136 181.438 1.00 43.36  ? 349 ASP D CG    1 
ATOM   3673  O OD1   . ASP B 2 367 ? 104.022 124.003 180.713 1.00 43.36  ? 349 ASP D OD1   1 
ATOM   3674  O OD2   . ASP B 2 367 ? 102.310 122.857 181.415 1.00 43.36  ? 349 ASP D OD2   1 
ATOM   3675  N N     . ARG B 2 368 ? 107.362 123.002 184.102 1.00 43.59  ? 350 ARG D N     1 
ATOM   3676  C CA    . ARG B 2 368 ? 108.559 122.315 184.585 1.00 43.59  ? 350 ARG D CA    1 
ATOM   3677  C C     . ARG B 2 368 ? 109.360 123.190 185.547 1.00 43.59  ? 350 ARG D C     1 
ATOM   3678  O O     . ARG B 2 368 ? 110.591 123.118 185.571 1.00 43.59  ? 350 ARG D O     1 
ATOM   3679  C CB    . ARG B 2 368 ? 109.432 121.865 183.411 1.00 43.59  ? 350 ARG D CB    1 
ATOM   3680  C CG    . ARG B 2 368 ? 109.896 122.987 182.472 1.00 43.59  ? 350 ARG D CG    1 
ATOM   3681  C CD    . ARG B 2 368 ? 110.537 122.468 181.187 1.00 43.59  ? 350 ARG D CD    1 
ATOM   3682  N NE    . ARG B 2 368 ? 111.998 122.518 181.275 1.00 43.59  ? 350 ARG D NE    1 
ATOM   3683  C CZ    . ARG B 2 368 ? 112.835 123.184 180.481 1.00 43.59  ? 350 ARG D CZ    1 
ATOM   3684  N NH1   . ARG B 2 368 ? 112.417 123.951 179.482 1.00 43.59  ? 350 ARG D NH1   1 
ATOM   3685  N NH2   . ARG B 2 368 ? 114.143 123.084 180.701 1.00 43.59  ? 350 ARG D NH2   1 
ATOM   3686  N N     . LEU B 2 369 ? 108.674 124.017 186.341 1.00 41.30  ? 351 LEU D N     1 
ATOM   3687  C CA    . LEU B 2 369 ? 109.277 124.848 187.378 1.00 41.30  ? 351 LEU D CA    1 
ATOM   3688  C C     . LEU B 2 369 ? 108.744 124.420 188.738 1.00 41.30  ? 351 LEU D C     1 
ATOM   3689  O O     . LEU B 2 369 ? 107.527 124.388 188.946 1.00 41.30  ? 351 LEU D O     1 
ATOM   3690  C CB    . LEU B 2 369 ? 108.962 126.332 187.152 1.00 41.30  ? 351 LEU D CB    1 
ATOM   3691  C CG    . LEU B 2 369 ? 109.666 127.148 186.058 1.00 41.30  ? 351 LEU D CG    1 
ATOM   3692  C CD1   . LEU B 2 369 ? 109.336 128.622 186.198 1.00 41.30  ? 351 LEU D CD1   1 
ATOM   3693  C CD2   . LEU B 2 369 ? 111.173 126.973 186.055 1.00 41.30  ? 351 LEU D CD2   1 
ATOM   3694  N N     . LEU B 2 370 ? 109.652 124.095 189.656 1.00 41.18  ? 352 LEU D N     1 
ATOM   3695  C CA    . LEU B 2 370 ? 109.304 123.893 191.062 1.00 41.18  ? 352 LEU D CA    1 
ATOM   3696  C C     . LEU B 2 370 ? 109.237 125.267 191.710 1.00 41.18  ? 352 LEU D C     1 
ATOM   3697  O O     . LEU B 2 370 ? 110.266 125.880 192.000 1.00 41.18  ? 352 LEU D O     1 
ATOM   3698  C CB    . LEU B 2 370 ? 110.331 123.010 191.763 1.00 41.18  ? 352 LEU D CB    1 
ATOM   3699  C CG    . LEU B 2 370 ? 110.367 121.491 191.540 1.00 41.18  ? 352 LEU D CG    1 
ATOM   3700  C CD1   . LEU B 2 370 ? 109.018 120.827 191.785 1.00 41.18  ? 352 LEU D CD1   1 
ATOM   3701  C CD2   . LEU B 2 370 ? 110.870 121.158 190.148 1.00 41.18  ? 352 LEU D CD2   1 
ATOM   3702  N N     . ILE B 2 371 ? 108.024 125.754 191.946 1.00 42.86  ? 353 ILE D N     1 
ATOM   3703  C CA    . ILE B 2 371 ? 107.808 127.117 192.417 1.00 42.86  ? 353 ILE D CA    1 
ATOM   3704  C C     . ILE B 2 371 ? 107.952 127.080 193.935 1.00 42.86  ? 353 ILE D C     1 
ATOM   3705  O O     . ILE B 2 371 ? 107.094 126.532 194.629 1.00 42.86  ? 353 ILE D O     1 
ATOM   3706  C CB    . ILE B 2 371 ? 106.433 127.646 191.971 1.00 42.86  ? 353 ILE D CB    1 
ATOM   3707  C CG1   . ILE B 2 371 ? 106.548 128.165 190.521 1.00 42.86  ? 353 ILE D CG1   1 
ATOM   3708  C CG2   . ILE B 2 371 ? 105.894 128.763 192.961 1.00 42.86  ? 353 ILE D CG2   1 
ATOM   3709  C CD1   . ILE B 2 371 ? 105.301 128.777 189.871 1.00 42.86  ? 353 ILE D CD1   1 
ATOM   3710  N N     . ILE B 2 372 ? 109.033 127.666 194.446 1.00 42.47  ? 354 ILE D N     1 
ATOM   3711  C CA    . ILE B 2 372 ? 109.197 127.905 195.877 1.00 42.47  ? 354 ILE D CA    1 
ATOM   3712  C C     . ILE B 2 372 ? 108.611 129.274 196.185 1.00 42.47  ? 354 ILE D C     1 
ATOM   3713  O O     . ILE B 2 372 ? 108.966 130.267 195.538 1.00 42.47  ? 354 ILE D O     1 
ATOM   3714  C CB    . ILE B 2 372 ? 110.678 127.828 196.292 1.00 42.47  ? 354 ILE D CB    1 
ATOM   3715  C CG1   . ILE B 2 372 ? 111.180 126.380 196.200 1.00 42.47  ? 354 ILE D CG1   1 
ATOM   3716  C CG2   . ILE B 2 372 ? 110.874 128.405 197.724 1.00 42.47  ? 354 ILE D CG2   1 
ATOM   3717  C CD1   . ILE B 2 372 ? 112.695 126.210 196.285 1.00 42.47  ? 354 ILE D CD1   1 
ATOM   3718  N N     . THR B 2 373 ? 107.721 129.323 197.176 1.00 42.98  ? 355 THR D N     1 
ATOM   3719  C CA    . THR B 2 373 ? 107.118 130.561 197.651 1.00 42.98  ? 355 THR D CA    1 
ATOM   3720  C C     . THR B 2 373 ? 107.776 130.979 198.961 1.00 42.98  ? 355 THR D C     1 
ATOM   3721  O O     . THR B 2 373 ? 108.067 130.138 199.818 1.00 42.98  ? 355 THR D O     1 
ATOM   3722  C CB    . THR B 2 373 ? 105.596 130.402 197.806 1.00 42.98  ? 355 THR D CB    1 
ATOM   3723  O OG1   . THR B 2 373 ? 104.964 131.681 197.669 1.00 42.98  ? 355 THR D OG1   1 
ATOM   3724  C CG2   . THR B 2 373 ? 105.185 129.757 199.139 1.00 42.98  ? 355 THR D CG2   1 
ATOM   3725  N N     . THR B 2 374 ? 108.044 132.279 199.087 1.00 44.19  ? 356 THR D N     1 
ATOM   3726  C CA    . THR B 2 374 ? 108.670 132.873 200.263 1.00 44.19  ? 356 THR D CA    1 
ATOM   3727  C C     . THR B 2 374 ? 107.636 133.733 200.975 1.00 44.19  ? 356 THR D C     1 
ATOM   3728  O O     . THR B 2 374 ? 107.090 134.669 200.383 1.00 44.19  ? 356 THR D O     1 
ATOM   3729  C CB    . THR B 2 374 ? 109.890 133.709 199.876 1.00 44.19  ? 356 THR D CB    1 
ATOM   3730  O OG1   . THR B 2 374 ? 109.520 134.672 198.886 1.00 44.19  ? 356 THR D OG1   1 
ATOM   3731  C CG2   . THR B 2 374 ? 110.990 132.822 199.319 1.00 44.19  ? 356 THR D CG2   1 
ATOM   3732  N N     . GLN B 2 375 ? 107.375 133.415 202.239 1.00 48.56  ? 357 GLN D N     1 
ATOM   3733  C CA    . GLN B 2 375 ? 106.352 134.095 203.013 1.00 48.56  ? 357 GLN D CA    1 
ATOM   3734  C C     . GLN B 2 375 ? 106.888 135.423 203.553 1.00 48.56  ? 357 GLN D C     1 
ATOM   3735  O O     . GLN B 2 375 ? 108.103 135.599 203.677 1.00 48.56  ? 357 GLN D O     1 
ATOM   3736  C CB    . GLN B 2 375 ? 105.898 133.203 204.164 1.00 48.56  ? 357 GLN D CB    1 
ATOM   3737  C CG    . GLN B 2 375 ? 105.458 131.808 203.738 1.00 48.56  ? 357 GLN D CG    1 
ATOM   3738  C CD    . GLN B 2 375 ? 104.824 131.028 204.874 1.00 48.56  ? 357 GLN D CD    1 
ATOM   3739  O OE1   . GLN B 2 375 ? 105.430 130.851 205.931 1.00 48.56  ? 357 GLN D OE1   1 
ATOM   3740  N NE2   . GLN B 2 375 ? 103.600 130.554 204.662 1.00 48.56  ? 357 GLN D NE2   1 
ATOM   3741  N N     . PRO B 2 376 ? 106.017 136.381 203.884 1.00 50.39  ? 358 PRO D N     1 
ATOM   3742  C CA    . PRO B 2 376 ? 106.514 137.630 204.473 1.00 50.39  ? 358 PRO D CA    1 
ATOM   3743  C C     . PRO B 2 376 ? 107.034 137.411 205.885 1.00 50.39  ? 358 PRO D C     1 
ATOM   3744  O O     . PRO B 2 376 ? 106.664 136.461 206.578 1.00 50.39  ? 358 PRO D O     1 
ATOM   3745  C CB    . PRO B 2 376 ? 105.288 138.547 204.467 1.00 50.39  ? 358 PRO D CB    1 
ATOM   3746  C CG    . PRO B 2 376 ? 104.142 137.631 204.501 1.00 50.39  ? 358 PRO D CG    1 
ATOM   3747  C CD    . PRO B 2 376 ? 104.552 136.434 203.704 1.00 50.39  ? 358 PRO D CD    1 
ATOM   3748  N N     . TYR B 2 377 ? 107.914 138.316 206.305 1.00 54.06  ? 359 TYR D N     1 
ATOM   3749  C CA    . TYR B 2 377 ? 108.524 138.210 207.623 1.00 54.06  ? 359 TYR D CA    1 
ATOM   3750  C C     . TYR B 2 377 ? 107.510 138.549 208.708 1.00 54.06  ? 359 TYR D C     1 
ATOM   3751  O O     . TYR B 2 377 ? 106.648 139.415 208.527 1.00 54.06  ? 359 TYR D O     1 
ATOM   3752  C CB    . TYR B 2 377 ? 109.727 139.156 207.733 1.00 54.06  ? 359 TYR D CB    1 
ATOM   3753  C CG    . TYR B 2 377 ? 111.051 138.664 207.156 1.00 54.06  ? 359 TYR D CG    1 
ATOM   3754  C CD1   . TYR B 2 377 ? 111.573 137.414 207.473 1.00 54.06  ? 359 TYR D CD1   1 
ATOM   3755  C CD2   . TYR B 2 377 ? 111.783 139.472 206.298 1.00 54.06  ? 359 TYR D CD2   1 
ATOM   3756  C CE1   . TYR B 2 377 ? 112.773 136.985 206.948 1.00 54.06  ? 359 TYR D CE1   1 
ATOM   3757  C CE2   . TYR B 2 377 ? 112.986 139.050 205.769 1.00 54.06  ? 359 TYR D CE2   1 
ATOM   3758  C CZ    . TYR B 2 377 ? 113.476 137.806 206.098 1.00 54.06  ? 359 TYR D CZ    1 
ATOM   3759  O OH    . TYR B 2 377 ? 114.674 137.381 205.573 1.00 54.06  ? 359 TYR D OH    1 
ATOM   3760  N N     . THR B 2 378 ? 107.625 137.861 209.843 1.00 60.80  ? 360 THR D N     1 
ATOM   3761  C CA    . THR B 2 378 ? 106.779 138.062 211.008 1.00 60.80  ? 360 THR D CA    1 
ATOM   3762  C C     . THR B 2 378 ? 107.484 138.992 211.997 1.00 60.80  ? 360 THR D C     1 
ATOM   3763  O O     . THR B 2 378 ? 108.546 139.551 211.707 1.00 60.80  ? 360 THR D O     1 
ATOM   3764  C CB    . THR B 2 378 ? 106.435 136.712 211.640 1.00 60.80  ? 360 THR D CB    1 
ATOM   3765  O OG1   . THR B 2 378 ? 107.622 136.115 212.177 1.00 60.80  ? 360 THR D OG1   1 
ATOM   3766  C CG2   . THR B 2 378 ? 105.824 135.778 210.606 1.00 60.80  ? 360 THR D CG2   1 
ATOM   3767  N N     . ASP B 2 379 ? 106.876 139.177 213.173 1.00 63.14  ? 361 ASP D N     1 
ATOM   3768  C CA    . ASP B 2 379 ? 107.462 140.061 214.183 1.00 63.14  ? 361 ASP D CA    1 
ATOM   3769  C C     . ASP B 2 379 ? 108.805 139.535 214.681 1.00 63.14  ? 361 ASP D C     1 
ATOM   3770  O O     . ASP B 2 379 ? 109.766 140.301 214.820 1.00 63.14  ? 361 ASP D O     1 
ATOM   3771  C CB    . ASP B 2 379 ? 106.497 140.261 215.363 1.00 63.14  ? 361 ASP D CB    1 
ATOM   3772  C CG    . ASP B 2 379 ? 106.006 138.951 215.985 1.00 63.14  ? 361 ASP D CG    1 
ATOM   3773  O OD1   . ASP B 2 379 ? 106.838 138.146 216.455 1.00 63.14  ? 361 ASP D OD1   1 
ATOM   3774  O OD2   . ASP B 2 379 ? 104.777 138.732 216.001 1.00 63.14  ? 361 ASP D OD2   1 
ATOM   3775  N N     . ASP B 2 380 ? 108.891 138.230 214.951 1.00 65.21  ? 362 ASP D N     1 
ATOM   3776  C CA    . ASP B 2 380 ? 110.110 137.673 215.527 1.00 65.21  ? 362 ASP D CA    1 
ATOM   3777  C C     . ASP B 2 380 ? 111.259 137.701 214.530 1.00 65.21  ? 362 ASP D C     1 
ATOM   3778  O O     . ASP B 2 380 ? 112.409 137.956 214.907 1.00 65.21  ? 362 ASP D O     1 
ATOM   3779  C CB    . ASP B 2 380 ? 109.852 136.245 216.010 1.00 65.21  ? 362 ASP D CB    1 
ATOM   3780  C CG    . ASP B 2 380 ? 110.917 135.739 216.976 1.00 65.21  ? 362 ASP D CG    1 
ATOM   3781  O OD1   . ASP B 2 380 ? 111.779 136.528 217.420 1.00 65.21  ? 362 ASP D OD1   1 
ATOM   3782  O OD2   . ASP B 2 380 ? 110.890 134.532 217.294 1.00 65.21  ? 362 ASP D OD2   1 
ATOM   3783  N N     . ASP B 2 381 ? 110.969 137.442 213.254 1.00 62.45  ? 363 ASP D N     1 
ATOM   3784  C CA    . ASP B 2 381 ? 112.011 137.497 212.234 1.00 62.45  ? 363 ASP D CA    1 
ATOM   3785  C C     . ASP B 2 381 ? 112.540 138.915 212.067 1.00 62.45  ? 363 ASP D C     1 
ATOM   3786  O O     . ASP B 2 381 ? 113.753 139.118 211.927 1.00 62.45  ? 363 ASP D O     1 
ATOM   3787  C CB    . ASP B 2 381 ? 111.477 136.963 210.906 1.00 62.45  ? 363 ASP D CB    1 
ATOM   3788  C CG    . ASP B 2 381 ? 110.911 135.561 211.025 1.00 62.45  ? 363 ASP D CG    1 
ATOM   3789  O OD1   . ASP B 2 381 ? 111.677 134.634 211.363 1.00 62.45  ? 363 ASP D OD1   1 
ATOM   3790  O OD2   . ASP B 2 381 ? 109.698 135.386 210.784 1.00 62.45  ? 363 ASP D OD2   1 
ATOM   3791  N N     . ILE B 2 382 ? 111.644 139.907 212.090 1.00 59.56  ? 364 ILE D N     1 
ATOM   3792  C CA    . ILE B 2 382 ? 112.065 141.304 212.004 1.00 59.56  ? 364 ILE D CA    1 
ATOM   3793  C C     . ILE B 2 382 ? 112.918 141.668 213.211 1.00 59.56  ? 364 ILE D C     1 
ATOM   3794  O O     . ILE B 2 382 ? 113.940 142.353 213.081 1.00 59.56  ? 364 ILE D O     1 
ATOM   3795  C CB    . ILE B 2 382 ? 110.836 142.230 211.872 1.00 59.56  ? 364 ILE D CB    1 
ATOM   3796  C CG1   . ILE B 2 382 ? 110.175 142.072 210.497 1.00 59.56  ? 364 ILE D CG1   1 
ATOM   3797  C CG2   . ILE B 2 382 ? 111.226 143.705 212.068 1.00 59.56  ? 364 ILE D CG2   1 
ATOM   3798  C CD1   . ILE B 2 382 ? 108.711 142.475 210.460 1.00 59.56  ? 364 ILE D CD1   1 
ATOM   3799  N N     . ARG B 2 383 ? 112.510 141.217 214.402 1.00 62.14  ? 365 ARG D N     1 
ATOM   3800  C CA    . ARG B 2 383 ? 113.269 141.511 215.614 1.00 62.14  ? 365 ARG D CA    1 
ATOM   3801  C C     . ARG B 2 383 ? 114.662 140.894 215.552 1.00 62.14  ? 365 ARG D C     1 
ATOM   3802  O O     . ARG B 2 383 ? 115.653 141.551 215.893 1.00 62.14  ? 365 ARG D O     1 
ATOM   3803  C CB    . ARG B 2 383 ? 112.489 141.009 216.835 1.00 62.14  ? 365 ARG D CB    1 
ATOM   3804  C CG    . ARG B 2 383 ? 113.227 140.999 218.180 1.00 62.14  ? 365 ARG D CG    1 
ATOM   3805  C CD    . ARG B 2 383 ? 113.802 142.362 218.542 1.00 62.14  ? 365 ARG D CD    1 
ATOM   3806  N NE    . ARG B 2 383 ? 114.350 142.376 219.894 1.00 62.14  ? 365 ARG D NE    1 
ATOM   3807  C CZ    . ARG B 2 383 ? 113.639 142.394 221.017 1.00 62.14  ? 365 ARG D CZ    1 
ATOM   3808  N NH1   . ARG B 2 383 ? 112.313 142.406 221.011 1.00 62.14  ? 365 ARG D NH1   1 
ATOM   3809  N NH2   . ARG B 2 383 ? 114.276 142.402 222.184 1.00 62.14  ? 365 ARG D NH2   1 
ATOM   3810  N N     . LYS B 2 384 ? 114.761 139.646 215.087 1.00 62.96  ? 366 LYS D N     1 
ATOM   3811  C CA    . LYS B 2 384 ? 116.062 138.993 214.977 1.00 62.96  ? 366 LYS D CA    1 
ATOM   3812  C C     . LYS B 2 384 ? 116.949 139.681 213.945 1.00 62.96  ? 366 LYS D C     1 
ATOM   3813  O O     . LYS B 2 384 ? 118.152 139.862 214.177 1.00 62.96  ? 366 LYS D O     1 
ATOM   3814  C CB    . LYS B 2 384 ? 115.878 137.518 214.621 1.00 62.96  ? 366 LYS D CB    1 
ATOM   3815  C CG    . LYS B 2 384 ? 115.416 136.638 215.786 1.00 62.96  ? 366 LYS D CG    1 
ATOM   3816  C CD    . LYS B 2 384 ? 115.719 135.152 215.570 1.00 62.96  ? 366 LYS D CD    1 
ATOM   3817  C CE    . LYS B 2 384 ? 114.809 134.517 214.525 1.00 62.96  ? 366 LYS D CE    1 
ATOM   3818  N NZ    . LYS B 2 384 ? 113.411 134.367 215.012 1.00 62.96  ? 366 LYS D NZ    1 
ATOM   3819  N N     . ILE B 2 385 ? 116.376 140.072 212.802 1.00 57.66  ? 367 ILE D N     1 
ATOM   3820  C CA    . ILE B 2 385 ? 117.169 140.714 211.756 1.00 57.66  ? 367 ILE D CA    1 
ATOM   3821  C C     . ILE B 2 385 ? 117.673 142.071 212.231 1.00 57.66  ? 367 ILE D C     1 
ATOM   3822  O O     . ILE B 2 385 ? 118.835 142.431 212.003 1.00 57.66  ? 367 ILE D O     1 
ATOM   3823  C CB    . ILE B 2 385 ? 116.354 140.840 210.452 1.00 57.66  ? 367 ILE D CB    1 
ATOM   3824  C CG1   . ILE B 2 385 ? 116.034 139.465 209.845 1.00 57.66  ? 367 ILE D CG1   1 
ATOM   3825  C CG2   . ILE B 2 385 ? 117.114 141.676 209.416 1.00 57.66  ? 367 ILE D CG2   1 
ATOM   3826  C CD1   . ILE B 2 385 ? 114.786 139.458 208.981 1.00 57.66  ? 367 ILE D CD1   1 
ATOM   3827  N N     . LEU B 2 386 ? 116.811 142.848 212.893 1.00 57.36  ? 368 LEU D N     1 
ATOM   3828  C CA    . LEU B 2 386 ? 117.244 144.140 213.410 1.00 57.36  ? 368 LEU D CA    1 
ATOM   3829  C C     . LEU B 2 386 ? 118.268 143.978 214.525 1.00 57.36  ? 368 LEU D C     1 
ATOM   3830  O O     . LEU B 2 386 ? 119.177 144.804 214.647 1.00 57.36  ? 368 LEU D O     1 
ATOM   3831  C CB    . LEU B 2 386 ? 116.037 144.944 213.895 1.00 57.36  ? 368 LEU D CB    1 
ATOM   3832  C CG    . LEU B 2 386 ? 114.994 145.327 212.836 1.00 57.36  ? 368 LEU D CG    1 
ATOM   3833  C CD1   . LEU B 2 386 ? 113.700 145.738 213.514 1.00 57.36  ? 368 LEU D CD1   1 
ATOM   3834  C CD2   . LEU B 2 386 ? 115.472 146.438 211.921 1.00 57.36  ? 368 LEU D CD2   1 
ATOM   3835  N N     . GLU B 2 387 ? 118.155 142.917 215.331 1.00 62.71  ? 369 GLU D N     1 
ATOM   3836  C CA    . GLU B 2 387 ? 119.175 142.645 216.340 1.00 62.71  ? 369 GLU D CA    1 
ATOM   3837  C C     . GLU B 2 387 ? 120.523 142.345 215.698 1.00 62.71  ? 369 GLU D C     1 
ATOM   3838  O O     . GLU B 2 387 ? 121.560 142.855 216.144 1.00 62.71  ? 369 GLU D O     1 
ATOM   3839  C CB    . GLU B 2 387 ? 118.740 141.474 217.224 1.00 62.71  ? 369 GLU D CB    1 
ATOM   3840  C CG    . GLU B 2 387 ? 119.315 141.505 218.629 1.00 62.71  ? 369 GLU D CG    1 
ATOM   3841  C CD    . GLU B 2 387 ? 118.657 142.547 219.509 1.00 62.71  ? 369 GLU D CD    1 
ATOM   3842  O OE1   . GLU B 2 387 ? 119.057 143.728 219.434 1.00 62.71  ? 369 GLU D OE1   1 
ATOM   3843  O OE2   . GLU B 2 387 ? 117.741 142.187 220.276 1.00 62.71  ? 369 GLU D OE2   1 
ATOM   3844  N N     . ILE B 2 388 ? 120.527 141.527 214.642 1.00 62.80  ? 370 ILE D N     1 
ATOM   3845  C CA    . ILE B 2 388 ? 121.780 141.197 213.965 1.00 62.80  ? 370 ILE D CA    1 
ATOM   3846  C C     . ILE B 2 388 ? 122.374 142.442 213.319 1.00 62.80  ? 370 ILE D C     1 
ATOM   3847  O O     . ILE B 2 388 ? 123.594 142.648 213.342 1.00 62.80  ? 370 ILE D O     1 
ATOM   3848  C CB    . ILE B 2 388 ? 121.579 140.067 212.932 1.00 62.80  ? 370 ILE D CB    1 
ATOM   3849  C CG1   . ILE B 2 388 ? 121.117 138.750 213.591 1.00 62.80  ? 370 ILE D CG1   1 
ATOM   3850  C CG2   . ILE B 2 388 ? 122.866 139.853 212.119 1.00 62.80  ? 370 ILE D CG2   1 
ATOM   3851  C CD1   . ILE B 2 388 ? 120.141 137.947 212.746 1.00 62.80  ? 370 ILE D CD1   1 
ATOM   3852  N N     . ARG B 2 389 ? 121.527 143.288 212.730 1.00 59.88  ? 371 ARG D N     1 
ATOM   3853  C CA    . ARG B 2 389 ? 122.032 144.498 212.090 1.00 59.88  ? 371 ARG D CA    1 
ATOM   3854  C C     . ARG B 2 389 ? 122.574 145.487 213.117 1.00 59.88  ? 371 ARG D C     1 
ATOM   3855  O O     . ARG B 2 389 ? 123.577 146.163 212.862 1.00 59.88  ? 371 ARG D O     1 
ATOM   3856  C CB    . ARG B 2 389 ? 120.928 145.139 211.244 1.00 59.88  ? 371 ARG D CB    1 
ATOM   3857  C CG    . ARG B 2 389 ? 121.322 146.405 210.466 1.00 59.88  ? 371 ARG D CG    1 
ATOM   3858  C CD    . ARG B 2 389 ? 122.591 146.252 209.629 1.00 59.88  ? 371 ARG D CD    1 
ATOM   3859  N NE    . ARG B 2 389 ? 122.659 144.966 208.938 1.00 59.88  ? 371 ARG D NE    1 
ATOM   3860  C CZ    . ARG B 2 389 ? 122.090 144.675 207.773 1.00 59.88  ? 371 ARG D CZ    1 
ATOM   3861  N NH1   . ARG B 2 389 ? 121.390 145.568 207.086 1.00 59.88  ? 371 ARG D NH1   1 
ATOM   3862  N NH2   . ARG B 2 389 ? 122.226 143.449 207.277 1.00 59.88  ? 371 ARG D NH2   1 
ATOM   3863  N N     . CYS B 2 390 ? 121.921 145.594 214.277 1.00 63.78  ? 372 CYS D N     1 
ATOM   3864  C CA    . CYS B 2 390 ? 122.438 146.451 215.338 1.00 63.78  ? 372 CYS D CA    1 
ATOM   3865  C C     . CYS B 2 390 ? 123.769 145.931 215.860 1.00 63.78  ? 372 CYS D C     1 
ATOM   3866  O O     . CYS B 2 390 ? 124.658 146.719 216.204 1.00 63.78  ? 372 CYS D O     1 
ATOM   3867  C CB    . CYS B 2 390 ? 121.422 146.555 216.474 1.00 63.78  ? 372 CYS D CB    1 
ATOM   3868  S SG    . CYS B 2 390 ? 120.052 147.682 216.144 1.00 63.78  ? 372 CYS D SG    1 
ATOM   3869  N N     . GLN B 2 391 ? 123.919 144.606 215.942 1.00 66.81  ? 373 GLN D N     1 
ATOM   3870  C CA    . GLN B 2 391 ? 125.214 144.035 216.301 1.00 66.81  ? 373 GLN D CA    1 
ATOM   3871  C C     . GLN B 2 391 ? 126.270 144.364 215.253 1.00 66.81  ? 373 GLN D C     1 
ATOM   3872  O O     . GLN B 2 391 ? 127.415 144.684 215.594 1.00 66.81  ? 373 GLN D O     1 
ATOM   3873  C CB    . GLN B 2 391 ? 125.090 142.522 216.473 1.00 66.81  ? 373 GLN D CB    1 
ATOM   3874  C CG    . GLN B 2 391 ? 124.414 142.099 217.764 1.00 66.81  ? 373 GLN D CG    1 
ATOM   3875  C CD    . GLN B 2 391 ? 124.361 140.593 217.925 1.00 66.81  ? 373 GLN D CD    1 
ATOM   3876  O OE1   . GLN B 2 391 ? 125.071 139.859 217.238 1.00 66.81  ? 373 GLN D OE1   1 
ATOM   3877  N NE2   . GLN B 2 391 ? 123.516 140.125 218.835 1.00 66.81  ? 373 GLN D NE2   1 
ATOM   3878  N N     . GLU B 2 392 ? 125.906 144.290 213.971 1.00 65.06  ? 374 GLU D N     1 
ATOM   3879  C CA    . GLU B 2 392 ? 126.870 144.564 212.911 1.00 65.06  ? 374 GLU D CA    1 
ATOM   3880  C C     . GLU B 2 392 ? 127.261 146.037 212.876 1.00 65.06  ? 374 GLU D C     1 
ATOM   3881  O O     . GLU B 2 392 ? 128.422 146.368 212.610 1.00 65.06  ? 374 GLU D O     1 
ATOM   3882  C CB    . GLU B 2 392 ? 126.301 144.129 211.560 1.00 65.06  ? 374 GLU D CB    1 
ATOM   3883  C CG    . GLU B 2 392 ? 126.327 142.624 211.335 1.00 65.06  ? 374 GLU D CG    1 
ATOM   3884  C CD    . GLU B 2 392 ? 125.936 142.236 209.922 1.00 65.06  ? 374 GLU D CD    1 
ATOM   3885  O OE1   . GLU B 2 392 ? 126.530 142.781 208.968 1.00 65.06  ? 374 GLU D OE1   1 
ATOM   3886  O OE2   . GLU B 2 392 ? 125.035 141.385 209.765 1.00 65.06  ? 374 GLU D OE2   1 
ATOM   3887  N N     . GLU B 2 393 ? 126.312 146.934 213.143 1.00 62.37  ? 375 GLU D N     1 
ATOM   3888  C CA    . GLU B 2 393 ? 126.563 148.371 213.095 1.00 62.37  ? 375 GLU D CA    1 
ATOM   3889  C C     . GLU B 2 393 ? 127.190 148.928 214.373 1.00 62.37  ? 375 GLU D C     1 
ATOM   3890  O O     . GLU B 2 393 ? 127.443 150.137 214.429 1.00 62.37  ? 375 GLU D O     1 
ATOM   3891  C CB    . GLU B 2 393 ? 125.255 149.116 212.804 1.00 62.37  ? 375 GLU D CB    1 
ATOM   3892  C CG    . GLU B 2 393 ? 124.712 148.901 211.392 1.00 62.37  ? 375 GLU D CG    1 
ATOM   3893  C CD    . GLU B 2 393 ? 125.447 149.703 210.327 1.00 62.37  ? 375 GLU D CD    1 
ATOM   3894  O OE1   . GLU B 2 393 ? 126.360 150.483 210.669 1.00 62.37  ? 375 GLU D OE1   1 
ATOM   3895  O OE2   . GLU B 2 393 ? 125.105 149.550 209.136 1.00 62.37  ? 375 GLU D OE2   1 
ATOM   3896  N N     . ASP B 2 394 ? 127.454 148.093 215.387 1.00 66.96  ? 376 ASP D N     1 
ATOM   3897  C CA    . ASP B 2 394 ? 128.008 148.541 216.669 1.00 66.96  ? 376 ASP D CA    1 
ATOM   3898  C C     . ASP B 2 394 ? 127.091 149.555 217.350 1.00 66.96  ? 376 ASP D C     1 
ATOM   3899  O O     . ASP B 2 394 ? 127.554 150.525 217.955 1.00 66.96  ? 376 ASP D O     1 
ATOM   3900  C CB    . ASP B 2 394 ? 129.416 149.117 216.497 1.00 66.96  ? 376 ASP D CB    1 
ATOM   3901  C CG    . ASP B 2 394 ? 130.323 148.207 215.694 1.00 66.96  ? 376 ASP D CG    1 
ATOM   3902  O OD1   . ASP B 2 394 ? 130.088 146.981 215.692 1.00 66.96  ? 376 ASP D OD1   1 
ATOM   3903  O OD2   . ASP B 2 394 ? 131.273 148.719 215.067 1.00 66.96  ? 376 ASP D OD2   1 
ATOM   3904  N N     . VAL B 2 395 ? 125.782 149.321 217.246 1.00 63.40  ? 377 VAL D N     1 
ATOM   3905  C CA    . VAL B 2 395 ? 124.745 150.167 217.831 1.00 63.40  ? 377 VAL D CA    1 
ATOM   3906  C C     . VAL B 2 395 ? 124.044 149.366 218.919 1.00 63.40  ? 377 VAL D C     1 
ATOM   3907  O O     . VAL B 2 395 ? 123.644 148.218 218.688 1.00 63.40  ? 377 VAL D O     1 
ATOM   3908  C CB    . VAL B 2 395 ? 123.740 150.645 216.768 1.00 63.40  ? 377 VAL D CB    1 
ATOM   3909  C CG1   . VAL B 2 395 ? 122.614 151.453 217.424 1.00 63.40  ? 377 VAL D CG1   1 
ATOM   3910  C CG2   . VAL B 2 395 ? 124.456 151.456 215.682 1.00 63.40  ? 377 VAL D CG2   1 
ATOM   3911  N N     . GLU B 2 396 ? 123.902 149.972 220.097 1.00 64.40  ? 378 GLU D N     1 
ATOM   3912  C CA    . GLU B 2 396 ? 123.259 149.363 221.257 1.00 64.40  ? 378 GLU D CA    1 
ATOM   3913  C C     . GLU B 2 396 ? 121.983 150.130 221.572 1.00 64.40  ? 378 GLU D C     1 
ATOM   3914  O O     . GLU B 2 396 ? 121.986 151.365 221.572 1.00 64.40  ? 378 GLU D O     1 
ATOM   3915  C CB    . GLU B 2 396 ? 124.200 149.367 222.463 1.00 64.40  ? 378 GLU D CB    1 
ATOM   3916  C CG    . GLU B 2 396 ? 125.499 148.607 222.230 1.00 64.40  ? 378 GLU D CG    1 
ATOM   3917  C CD    . GLU B 2 396 ? 126.364 148.525 223.472 1.00 64.40  ? 378 GLU D CD    1 
ATOM   3918  O OE1   . GLU B 2 396 ? 126.024 149.177 224.481 1.00 64.40  ? 378 GLU D OE1   1 
ATOM   3919  O OE2   . GLU B 2 396 ? 127.386 147.807 223.439 1.00 64.40  ? 378 GLU D OE2   1 
ATOM   3920  N N     . MET B 2 397 ? 120.901 149.394 221.837 1.00 62.24  ? 379 MET D N     1 
ATOM   3921  C CA    . MET B 2 397 ? 119.575 149.967 222.028 1.00 62.24  ? 379 MET D CA    1 
ATOM   3922  C C     . MET B 2 397 ? 118.848 149.234 223.143 1.00 62.24  ? 379 MET D C     1 
ATOM   3923  O O     . MET B 2 397 ? 119.001 148.022 223.314 1.00 62.24  ? 379 MET D O     1 
ATOM   3924  C CB    . MET B 2 397 ? 118.750 149.887 220.740 1.00 62.24  ? 379 MET D CB    1 
ATOM   3925  C CG    . MET B 2 397 ? 118.925 151.086 219.839 1.00 62.24  ? 379 MET D CG    1 
ATOM   3926  S SD    . MET B 2 397 ? 118.643 150.745 218.094 1.00 62.24  ? 379 MET D SD    1 
ATOM   3927  C CE    . MET B 2 397 ? 117.034 149.969 218.163 1.00 62.24  ? 379 MET D CE    1 
ATOM   3928  N N     . ASN B 2 398 ? 118.046 149.983 223.897 1.00 64.65  ? 380 ASN D N     1 
ATOM   3929  C CA    . ASN B 2 398 ? 117.249 149.387 224.960 1.00 64.65  ? 380 ASN D CA    1 
ATOM   3930  C C     . ASN B 2 398 ? 116.080 148.600 224.365 1.00 64.65  ? 380 ASN D C     1 
ATOM   3931  O O     . ASN B 2 398 ? 115.797 148.657 223.166 1.00 64.65  ? 380 ASN D O     1 
ATOM   3932  C CB    . ASN B 2 398 ? 116.764 150.460 225.947 1.00 64.65  ? 380 ASN D CB    1 
ATOM   3933  C CG    . ASN B 2 398 ? 115.902 151.549 225.297 1.00 64.65  ? 380 ASN D CG    1 
ATOM   3934  O OD1   . ASN B 2 398 ? 114.854 151.277 224.709 1.00 64.65  ? 380 ASN D OD1   1 
ATOM   3935  N ND2   . ASN B 2 398 ? 116.349 152.795 225.413 1.00 64.65  ? 380 ASN D ND2   1 
ATOM   3936  N N     . GLU B 2 399 ? 115.392 147.854 225.233 1.00 69.44  ? 381 GLU D N     1 
ATOM   3937  C CA    . GLU B 2 399 ? 114.330 146.971 224.764 1.00 69.44  ? 381 GLU D CA    1 
ATOM   3938  C C     . GLU B 2 399 ? 113.109 147.744 224.282 1.00 69.44  ? 381 GLU D C     1 
ATOM   3939  O O     . GLU B 2 399 ? 112.415 147.283 223.368 1.00 69.44  ? 381 GLU D O     1 
ATOM   3940  C CB    . GLU B 2 399 ? 113.931 145.996 225.873 1.00 69.44  ? 381 GLU D CB    1 
ATOM   3941  C CG    . GLU B 2 399 ? 114.935 144.866 226.121 1.00 69.44  ? 381 GLU D CG    1 
ATOM   3942  C CD    . GLU B 2 399 ? 114.998 143.848 224.989 1.00 69.44  ? 381 GLU D CD    1 
ATOM   3943  O OE1   . GLU B 2 399 ? 113.981 143.658 224.289 1.00 69.44  ? 381 GLU D OE1   1 
ATOM   3944  O OE2   . GLU B 2 399 ? 116.071 143.237 224.801 1.00 69.44  ? 381 GLU D OE2   1 
ATOM   3945  N N     . GLU B 2 400 ? 112.817 148.900 224.884 1.00 65.62  ? 382 GLU D N     1 
ATOM   3946  C CA    . GLU B 2 400 ? 111.673 149.695 224.444 1.00 65.62  ? 382 GLU D CA    1 
ATOM   3947  C C     . GLU B 2 400 ? 111.877 150.210 223.024 1.00 65.62  ? 382 GLU D C     1 
ATOM   3948  O O     . GLU B 2 400 ? 110.979 150.105 222.177 1.00 65.62  ? 382 GLU D O     1 
ATOM   3949  C CB    . GLU B 2 400 ? 111.442 150.860 225.406 1.00 65.62  ? 382 GLU D CB    1 
ATOM   3950  C CG    . GLU B 2 400 ? 110.058 151.484 225.297 1.00 65.62  ? 382 GLU D CG    1 
ATOM   3951  C CD    . GLU B 2 400 ? 109.861 152.649 226.248 1.00 65.62  ? 382 GLU D CD    1 
ATOM   3952  O OE1   . GLU B 2 400 ? 110.855 153.331 226.575 1.00 65.62  ? 382 GLU D OE1   1 
ATOM   3953  O OE2   . GLU B 2 400 ? 108.709 152.885 226.668 1.00 65.62  ? 382 GLU D OE2   1 
ATOM   3954  N N     . ALA B 2 401 ? 113.061 150.761 222.745 1.00 63.48  ? 383 ALA D N     1 
ATOM   3955  C CA    . ALA B 2 401 ? 113.367 151.218 221.395 1.00 63.48  ? 383 ALA D CA    1 
ATOM   3956  C C     . ALA B 2 401 ? 113.404 150.052 220.419 1.00 63.48  ? 383 ALA D C     1 
ATOM   3957  O O     . ALA B 2 401 ? 112.994 150.191 219.263 1.00 63.48  ? 383 ALA D O     1 
ATOM   3958  C CB    . ALA B 2 401 ? 114.699 151.967 221.383 1.00 63.48  ? 383 ALA D CB    1 
ATOM   3959  N N     . LYS B 2 402 ? 113.884 148.891 220.872 1.00 62.48  ? 384 LYS D N     1 
ATOM   3960  C CA    . LYS B 2 402 ? 113.918 147.710 220.015 1.00 62.48  ? 384 LYS D CA    1 
ATOM   3961  C C     . LYS B 2 402 ? 112.512 147.269 219.625 1.00 62.48  ? 384 LYS D C     1 
ATOM   3962  O O     . LYS B 2 402 ? 112.248 146.970 218.455 1.00 62.48  ? 384 LYS D O     1 
ATOM   3963  C CB    . LYS B 2 402 ? 114.651 146.573 220.729 1.00 62.48  ? 384 LYS D CB    1 
ATOM   3964  C CG    . LYS B 2 402 ? 115.244 145.488 219.814 1.00 62.48  ? 384 LYS D CG    1 
ATOM   3965  C CD    . LYS B 2 402 ? 116.415 145.946 218.920 1.00 62.48  ? 384 LYS D CD    1 
ATOM   3966  C CE    . LYS B 2 402 ? 117.582 146.568 219.687 1.00 62.48  ? 384 LYS D CE    1 
ATOM   3967  N NZ    . LYS B 2 402 ? 118.004 145.763 220.866 1.00 62.48  ? 384 LYS D NZ    1 
ATOM   3968  N N     . GLN B 2 403 ? 111.592 147.235 220.591 1.00 63.38  ? 385 GLN D N     1 
ATOM   3969  C CA    . GLN B 2 403 ? 110.218 146.841 220.297 1.00 63.38  ? 385 GLN D CA    1 
ATOM   3970  C C     . GLN B 2 403 ? 109.522 147.870 219.414 1.00 63.38  ? 385 GLN D C     1 
ATOM   3971  O O     . GLN B 2 403 ? 108.749 147.507 218.515 1.00 63.38  ? 385 GLN D O     1 
ATOM   3972  C CB    . GLN B 2 403 ? 109.452 146.637 221.604 1.00 63.38  ? 385 GLN D CB    1 
ATOM   3973  C CG    . GLN B 2 403 ? 108.073 146.003 221.443 1.00 63.38  ? 385 GLN D CG    1 
ATOM   3974  C CD    . GLN B 2 403 ? 106.936 147.005 221.546 1.00 63.38  ? 385 GLN D CD    1 
ATOM   3975  O OE1   . GLN B 2 403 ? 107.081 148.173 221.186 1.00 63.38  ? 385 GLN D OE1   1 
ATOM   3976  N NE2   . GLN B 2 403 ? 105.793 146.548 222.044 1.00 63.38  ? 385 GLN D NE2   1 
ATOM   3977  N N     . LEU B 2 404 ? 109.780 149.160 219.658 1.00 61.55  ? 386 LEU D N     1 
ATOM   3978  C CA    . LEU B 2 404 ? 109.186 150.204 218.828 1.00 61.55  ? 386 LEU D CA    1 
ATOM   3979  C C     . LEU B 2 404 ? 109.694 150.087 217.393 1.00 61.55  ? 386 LEU D C     1 
ATOM   3980  O O     . LEU B 2 404 ? 108.921 150.199 216.435 1.00 61.55  ? 386 LEU D O     1 
ATOM   3981  C CB    . LEU B 2 404 ? 109.526 151.578 219.414 1.00 61.55  ? 386 LEU D CB    1 
ATOM   3982  C CG    . LEU B 2 404 ? 109.425 152.868 218.592 1.00 61.55  ? 386 LEU D CG    1 
ATOM   3983  C CD1   . LEU B 2 404 ? 108.119 152.945 217.797 1.00 61.55  ? 386 LEU D CD1   1 
ATOM   3984  C CD2   . LEU B 2 404 ? 109.584 154.071 219.495 1.00 61.55  ? 386 LEU D CD2   1 
ATOM   3985  N N     . LEU B 2 405 ? 110.991 149.820 217.233 1.00 56.57  ? 387 LEU D N     1 
ATOM   3986  C CA    . LEU B 2 405 ? 111.561 149.620 215.908 1.00 56.57  ? 387 LEU D CA    1 
ATOM   3987  C C     . LEU B 2 405 ? 111.015 148.367 215.239 1.00 56.57  ? 387 LEU D C     1 
ATOM   3988  O O     . LEU B 2 405 ? 110.856 148.344 214.016 1.00 56.57  ? 387 LEU D O     1 
ATOM   3989  C CB    . LEU B 2 405 ? 113.081 149.538 216.015 1.00 56.57  ? 387 LEU D CB    1 
ATOM   3990  C CG    . LEU B 2 405 ? 113.891 149.707 214.725 1.00 56.57  ? 387 LEU D CG    1 
ATOM   3991  C CD1   . LEU B 2 405 ? 113.793 151.130 214.190 1.00 56.57  ? 387 LEU D CD1   1 
ATOM   3992  C CD2   . LEU B 2 405 ? 115.358 149.331 214.919 1.00 56.57  ? 387 LEU D CD2   1 
ATOM   3993  N N     . THR B 2 406 ? 110.740 147.315 216.013 1.00 59.30  ? 388 THR D N     1 
ATOM   3994  C CA    . THR B 2 406 ? 110.111 146.126 215.445 1.00 59.30  ? 388 THR D CA    1 
ATOM   3995  C C     . THR B 2 406 ? 108.716 146.457 214.927 1.00 59.30  ? 388 THR D C     1 
ATOM   3996  O O     . THR B 2 406 ? 108.308 145.976 213.863 1.00 59.30  ? 388 THR D O     1 
ATOM   3997  C CB    . THR B 2 406 ? 110.074 145.009 216.499 1.00 59.30  ? 388 THR D CB    1 
ATOM   3998  O OG1   . THR B 2 406 ? 111.349 144.357 216.540 1.00 59.30  ? 388 THR D OG1   1 
ATOM   3999  C CG2   . THR B 2 406 ? 109.006 143.936 216.202 1.00 59.30  ? 388 THR D CG2   1 
ATOM   4000  N N     . LEU B 2 407 ? 107.970 147.277 215.669 1.00 63.15  ? 389 LEU D N     1 
ATOM   4001  C CA    . LEU B 2 407 ? 106.649 147.696 215.201 1.00 63.15  ? 389 LEU D CA    1 
ATOM   4002  C C     . LEU B 2 407 ? 106.756 148.543 213.934 1.00 63.15  ? 389 LEU D C     1 
ATOM   4003  O O     . LEU B 2 407 ? 105.934 148.410 213.014 1.00 63.15  ? 389 LEU D O     1 
ATOM   4004  C CB    . LEU B 2 407 ? 105.918 148.468 216.302 1.00 63.15  ? 389 LEU D CB    1 
ATOM   4005  C CG    . LEU B 2 407 ? 105.056 147.672 217.292 1.00 63.15  ? 389 LEU D CG    1 
ATOM   4006  C CD1   . LEU B 2 407 ? 104.569 148.576 218.414 1.00 63.15  ? 389 LEU D CD1   1 
ATOM   4007  C CD2   . LEU B 2 407 ? 103.863 147.006 216.612 1.00 63.15  ? 389 LEU D CD2   1 
ATOM   4008  N N     . ILE B 2 408 ? 107.763 149.421 213.874 1.00 57.37  ? 390 ILE D N     1 
ATOM   4009  C CA    . ILE B 2 408 ? 107.999 150.218 212.670 1.00 57.37  ? 390 ILE D CA    1 
ATOM   4010  C C     . ILE B 2 408 ? 108.328 149.307 211.495 1.00 57.37  ? 390 ILE D C     1 
ATOM   4011  O O     . ILE B 2 408 ? 107.860 149.525 210.373 1.00 57.37  ? 390 ILE D O     1 
ATOM   4012  C CB    . ILE B 2 408 ? 109.120 151.255 212.912 1.00 57.37  ? 390 ILE D CB    1 
ATOM   4013  C CG1   . ILE B 2 408 ? 108.638 152.390 213.817 1.00 57.37  ? 390 ILE D CG1   1 
ATOM   4014  C CG2   . ILE B 2 408 ? 109.620 151.873 211.599 1.00 57.37  ? 390 ILE D CG2   1 
ATOM   4015  C CD1   . ILE B 2 408 ? 109.751 153.042 214.619 1.00 57.37  ? 390 ILE D CD1   1 
ATOM   4016  N N     . GLY B 2 409 ? 109.148 148.284 211.730 1.00 57.12  ? 391 GLY D N     1 
ATOM   4017  C CA    . GLY B 2 409 ? 109.491 147.360 210.663 1.00 57.12  ? 391 GLY D CA    1 
ATOM   4018  C C     . GLY B 2 409 ? 108.300 146.556 210.183 1.00 57.12  ? 391 GLY D C     1 
ATOM   4019  O O     . GLY B 2 409 ? 108.193 146.238 208.996 1.00 57.12  ? 391 GLY D O     1 
ATOM   4020  N N     . ARG B 2 410 ? 107.399 146.198 211.101 1.00 60.81  ? 392 ARG D N     1 
ATOM   4021  C CA    . ARG B 2 410 ? 106.167 145.524 210.703 1.00 60.81  ? 392 ARG D CA    1 
ATOM   4022  C C     . ARG B 2 410 ? 105.313 146.420 209.818 1.00 60.81  ? 392 ARG D C     1 
ATOM   4023  O O     . ARG B 2 410 ? 104.902 146.020 208.722 1.00 60.81  ? 392 ARG D O     1 
ATOM   4024  C CB    . ARG B 2 410 ? 105.363 145.100 211.934 1.00 60.81  ? 392 ARG D CB    1 
ATOM   4025  C CG    . ARG B 2 410 ? 105.759 143.772 212.567 1.00 60.81  ? 392 ARG D CG    1 
ATOM   4026  C CD    . ARG B 2 410 ? 104.535 142.971 213.013 1.00 60.81  ? 392 ARG D CD    1 
ATOM   4027  N NE    . ARG B 2 410 ? 103.781 143.627 214.085 1.00 60.81  ? 392 ARG D NE    1 
ATOM   4028  C CZ    . ARG B 2 410 ? 102.653 144.324 213.961 1.00 60.81  ? 392 ARG D CZ    1 
ATOM   4029  N NH1   . ARG B 2 410 ? 102.069 144.530 212.788 1.00 60.81  ? 392 ARG D NH1   1 
ATOM   4030  N NH2   . ARG B 2 410 ? 102.086 144.828 215.053 1.00 60.81  ? 392 ARG D NH2   1 
ATOM   4031  N N     . ASP B 2 411 ? 105.042 147.643 210.273 1.00 61.91  ? 393 ASP D N     1 
ATOM   4032  C CA    . ASP B 2 411 ? 104.068 148.492 209.595 1.00 61.91  ? 393 ASP D CA    1 
ATOM   4033  C C     . ASP B 2 411 ? 104.629 149.254 208.395 1.00 61.91  ? 393 ASP D C     1 
ATOM   4034  O O     . ASP B 2 411 ? 103.833 149.783 207.612 1.00 61.91  ? 393 ASP D O     1 
ATOM   4035  C CB    . ASP B 2 411 ? 103.467 149.478 210.597 1.00 61.91  ? 393 ASP D CB    1 
ATOM   4036  C CG    . ASP B 2 411 ? 102.865 148.782 211.801 1.00 61.91  ? 393 ASP D CG    1 
ATOM   4037  O OD1   . ASP B 2 411 ? 103.324 147.669 212.133 1.00 61.91  ? 393 ASP D OD1   1 
ATOM   4038  O OD2   . ASP B 2 411 ? 101.929 149.341 212.413 1.00 61.91  ? 393 ASP D OD2   1 
ATOM   4039  N N     . THR B 2 412 ? 105.962 149.326 208.229 1.00 55.51  ? 394 THR D N     1 
ATOM   4040  C CA    . THR B 2 412 ? 106.606 150.086 207.158 1.00 55.51  ? 394 THR D CA    1 
ATOM   4041  C C     . THR B 2 412 ? 107.743 149.294 206.513 1.00 55.51  ? 394 THR D C     1 
ATOM   4042  O O     . THR B 2 412 ? 108.729 149.883 206.056 1.00 55.51  ? 394 THR D O     1 
ATOM   4043  C CB    . THR B 2 412 ? 107.153 151.424 207.682 1.00 55.51  ? 394 THR D CB    1 
ATOM   4044  O OG1   . THR B 2 412 ? 108.045 151.174 208.772 1.00 55.51  ? 394 THR D OG1   1 
ATOM   4045  C CG2   . THR B 2 412 ? 106.045 152.351 208.144 1.00 55.51  ? 394 THR D CG2   1 
ATOM   4046  N N     . SER B 2 413 ? 107.640 147.962 206.490 1.00 54.31  ? 395 SER D N     1 
ATOM   4047  C CA    . SER B 2 413 ? 108.653 147.080 205.908 1.00 54.31  ? 395 SER D CA    1 
ATOM   4048  C C     . SER B 2 413 ? 109.983 147.118 206.660 1.00 54.31  ? 395 SER D C     1 
ATOM   4049  O O     . SER B 2 413 ? 110.274 148.057 207.407 1.00 54.31  ? 395 SER D O     1 
ATOM   4050  C CB    . SER B 2 413 ? 108.887 147.416 204.431 1.00 54.31  ? 395 SER D CB    1 
ATOM   4051  O OG    . SER B 2 413 ? 109.881 148.416 204.294 1.00 54.31  ? 395 SER D OG    1 
ATOM   4052  N N     . LEU B 2 414 ? 110.802 146.087 206.462 1.00 53.24  ? 396 LEU D N     1 
ATOM   4053  C CA    . LEU B 2 414 ? 112.003 145.918 207.271 1.00 53.24  ? 396 LEU D CA    1 
ATOM   4054  C C     . LEU B 2 414 ? 113.113 146.880 206.861 1.00 53.24  ? 396 LEU D C     1 
ATOM   4055  O O     . LEU B 2 414 ? 113.850 147.380 207.720 1.00 53.24  ? 396 LEU D O     1 
ATOM   4056  C CB    . LEU B 2 414 ? 112.479 144.469 207.169 1.00 53.24  ? 396 LEU D CB    1 
ATOM   4057  C CG    . LEU B 2 414 ? 113.773 144.087 207.886 1.00 53.24  ? 396 LEU D CG    1 
ATOM   4058  C CD1   . LEU B 2 414 ? 113.585 142.757 208.583 1.00 53.24  ? 396 LEU D CD1   1 
ATOM   4059  C CD2   . LEU B 2 414 ? 114.949 144.008 206.924 1.00 53.24  ? 396 LEU D CD2   1 
ATOM   4060  N N     . ARG B 2 415 ? 113.244 147.151 205.559 1.00 51.26  ? 397 ARG D N     1 
ATOM   4061  C CA    . ARG B 2 415 ? 114.361 147.948 205.056 1.00 51.26  ? 397 ARG D CA    1 
ATOM   4062  C C     . ARG B 2 415 ? 114.308 149.384 205.568 1.00 51.26  ? 397 ARG D C     1 
ATOM   4063  O O     . ARG B 2 415 ? 115.356 149.998 205.815 1.00 51.26  ? 397 ARG D O     1 
ATOM   4064  C CB    . ARG B 2 415 ? 114.348 147.917 203.527 1.00 51.26  ? 397 ARG D CB    1 
ATOM   4065  C CG    . ARG B 2 415 ? 115.580 148.472 202.824 1.00 51.26  ? 397 ARG D CG    1 
ATOM   4066  C CD    . ARG B 2 415 ? 116.785 147.541 202.903 1.00 51.26  ? 397 ARG D CD    1 
ATOM   4067  N NE    . ARG B 2 415 ? 118.040 148.288 202.885 1.00 51.26  ? 397 ARG D NE    1 
ATOM   4068  C CZ    . ARG B 2 415 ? 119.214 147.854 203.334 1.00 51.26  ? 397 ARG D CZ    1 
ATOM   4069  N NH1   . ARG B 2 415 ? 119.374 146.632 203.826 1.00 51.26  ? 397 ARG D NH1   1 
ATOM   4070  N NH2   . ARG B 2 415 ? 120.265 148.667 203.278 1.00 51.26  ? 397 ARG D NH2   1 
ATOM   4071  N N     . TYR B 2 416 ? 113.104 149.931 205.732 1.00 46.95  ? 398 TYR D N     1 
ATOM   4072  C CA    . TYR B 2 416 ? 112.971 151.264 206.304 1.00 46.95  ? 398 TYR D CA    1 
ATOM   4073  C C     . TYR B 2 416 ? 113.464 151.286 207.746 1.00 46.95  ? 398 TYR D C     1 
ATOM   4074  O O     . TYR B 2 416 ? 114.119 152.243 208.170 1.00 46.95  ? 398 TYR D O     1 
ATOM   4075  C CB    . TYR B 2 416 ? 111.516 151.712 206.206 1.00 46.95  ? 398 TYR D CB    1 
ATOM   4076  C CG    . TYR B 2 416 ? 111.178 152.966 206.967 1.00 46.95  ? 398 TYR D CG    1 
ATOM   4077  C CD1   . TYR B 2 416 ? 111.499 154.214 206.460 1.00 46.95  ? 398 TYR D CD1   1 
ATOM   4078  C CD2   . TYR B 2 416 ? 110.506 152.905 208.174 1.00 46.95  ? 398 TYR D CD2   1 
ATOM   4079  C CE1   . TYR B 2 416 ? 111.179 155.363 207.145 1.00 46.95  ? 398 TYR D CE1   1 
ATOM   4080  C CE2   . TYR B 2 416 ? 110.178 154.047 208.864 1.00 46.95  ? 398 TYR D CE2   1 
ATOM   4081  C CZ    . TYR B 2 416 ? 110.515 155.274 208.345 1.00 46.95  ? 398 TYR D CZ    1 
ATOM   4082  O OH    . TYR B 2 416 ? 110.194 156.418 209.034 1.00 46.95  ? 398 TYR D OH    1 
ATOM   4083  N N     . ALA B 2 417 ? 113.182 150.226 208.508 1.00 49.31  ? 399 ALA D N     1 
ATOM   4084  C CA    . ALA B 2 417 ? 113.719 150.125 209.862 1.00 49.31  ? 399 ALA D CA    1 
ATOM   4085  C C     . ALA B 2 417 ? 115.238 149.996 209.848 1.00 49.31  ? 399 ALA D C     1 
ATOM   4086  O O     . ALA B 2 417 ? 115.920 150.518 210.740 1.00 49.31  ? 399 ALA D O     1 
ATOM   4087  C CB    . ALA B 2 417 ? 113.088 148.937 210.585 1.00 49.31  ? 399 ALA D CB    1 
ATOM   4088  N N     . ILE B 2 418 ? 115.785 149.298 208.848 1.00 52.55  ? 400 ILE D N     1 
ATOM   4089  C CA    . ILE B 2 418 ? 117.240 149.190 208.724 1.00 52.55  ? 400 ILE D CA    1 
ATOM   4090  C C     . ILE B 2 418 ? 117.858 150.564 208.483 1.00 52.55  ? 400 ILE D C     1 
ATOM   4091  O O     . ILE B 2 418 ? 118.913 150.890 209.040 1.00 52.55  ? 400 ILE D O     1 
ATOM   4092  C CB    . ILE B 2 418 ? 117.618 148.192 207.607 1.00 52.55  ? 400 ILE D CB    1 
ATOM   4093  C CG1   . ILE B 2 418 ? 117.155 146.757 207.926 1.00 52.55  ? 400 ILE D CG1   1 
ATOM   4094  C CG2   . ILE B 2 418 ? 119.121 148.206 207.346 1.00 52.55  ? 400 ILE D CG2   1 
ATOM   4095  C CD1   . ILE B 2 418 ? 117.939 146.028 209.014 1.00 52.55  ? 400 ILE D CD1   1 
ATOM   4096  N N     . HIS B 2 419 ? 117.221 151.382 207.643 1.00 46.80  ? 401 HIS D N     1 
ATOM   4097  C CA    . HIS B 2 419 ? 117.695 152.754 207.453 1.00 46.80  ? 401 HIS D CA    1 
ATOM   4098  C C     . HIS B 2 419 ? 117.556 153.569 208.737 1.00 46.80  ? 401 HIS D C     1 
ATOM   4099  O O     . HIS B 2 419 ? 118.441 154.371 209.080 1.00 46.80  ? 401 HIS D O     1 
ATOM   4100  C CB    . HIS B 2 419 ? 116.922 153.427 206.316 1.00 46.80  ? 401 HIS D CB    1 
ATOM   4101  C CG    . HIS B 2 419 ? 117.254 152.904 204.950 1.00 46.80  ? 401 HIS D CG    1 
ATOM   4102  N ND1   . HIS B 2 419 ? 116.583 153.318 203.820 1.00 46.80  ? 401 HIS D ND1   1 
ATOM   4103  C CD2   . HIS B 2 419 ? 118.173 152.002 204.530 1.00 46.80  ? 401 HIS D CD2   1 
ATOM   4104  C CE1   . HIS B 2 419 ? 117.078 152.699 202.764 1.00 46.80  ? 401 HIS D CE1   1 
ATOM   4105  N NE2   . HIS B 2 419 ? 118.044 151.895 203.167 1.00 46.80  ? 401 HIS D NE2   1 
ATOM   4106  N N     . LEU B 2 420 ? 116.447 153.380 209.458 1.00 46.92  ? 402 LEU D N     1 
ATOM   4107  C CA    . LEU B 2 420 ? 116.231 154.132 210.688 1.00 46.92  ? 402 LEU D CA    1 
ATOM   4108  C C     . LEU B 2 420 ? 117.236 153.764 211.767 1.00 46.92  ? 402 LEU D C     1 
ATOM   4109  O O     . LEU B 2 420 ? 117.494 154.582 212.650 1.00 46.92  ? 402 LEU D O     1 
ATOM   4110  C CB    . LEU B 2 420 ? 114.816 153.910 211.228 1.00 46.92  ? 402 LEU D CB    1 
ATOM   4111  C CG    . LEU B 2 420 ? 113.528 154.408 210.547 1.00 46.92  ? 402 LEU D CG    1 
ATOM   4112  C CD1   . LEU B 2 420 ? 112.493 154.713 211.631 1.00 46.92  ? 402 LEU D CD1   1 
ATOM   4113  C CD2   . LEU B 2 420 ? 113.668 155.601 209.579 1.00 46.92  ? 402 LEU D CD2   1 
ATOM   4114  N N     . ILE B 2 421 ? 117.799 152.552 211.728 1.00 51.98  ? 403 ILE D N     1 
ATOM   4115  C CA    . ILE B 2 421 ? 118.842 152.192 212.691 1.00 51.98  ? 403 ILE D CA    1 
ATOM   4116  C C     . ILE B 2 421 ? 120.047 153.113 212.530 1.00 51.98  ? 403 ILE D C     1 
ATOM   4117  O O     . ILE B 2 421 ? 120.543 153.690 213.505 1.00 51.98  ? 403 ILE D O     1 
ATOM   4118  C CB    . ILE B 2 421 ? 119.233 150.708 212.535 1.00 51.98  ? 403 ILE D CB    1 
ATOM   4119  C CG1   . ILE B 2 421 ? 118.176 149.828 213.192 1.00 51.98  ? 403 ILE D CG1   1 
ATOM   4120  C CG2   . ILE B 2 421 ? 120.596 150.388 213.191 1.00 51.98  ? 403 ILE D CG2   1 
ATOM   4121  C CD1   . ILE B 2 421 ? 118.088 148.432 212.623 1.00 51.98  ? 403 ILE D CD1   1 
ATOM   4122  N N     . THR B 2 422 ? 120.521 153.278 211.293 1.00 46.71  ? 404 THR D N     1 
ATOM   4123  C CA    . THR B 2 422 ? 121.661 154.155 211.044 1.00 46.71  ? 404 THR D CA    1 
ATOM   4124  C C     . THR B 2 422 ? 121.319 155.608 211.350 1.00 46.71  ? 404 THR D C     1 
ATOM   4125  O O     . THR B 2 422 ? 122.122 156.326 211.966 1.00 46.71  ? 404 THR D O     1 
ATOM   4126  C CB    . THR B 2 422 ? 122.120 154.008 209.594 1.00 46.71  ? 404 THR D CB    1 
ATOM   4127  O OG1   . THR B 2 422 ? 122.361 152.626 209.305 1.00 46.71  ? 404 THR D OG1   1 
ATOM   4128  C CG2   . THR B 2 422 ? 123.391 154.802 209.341 1.00 46.71  ? 404 THR D CG2   1 
ATOM   4129  N N     . ALA B 2 423 ? 120.125 156.053 210.940 1.00 44.87  ? 405 ALA D N     1 
ATOM   4130  C CA    . ALA B 2 423 ? 119.733 157.440 211.183 1.00 44.87  ? 405 ALA D CA    1 
ATOM   4131  C C     . ALA B 2 423 ? 119.614 157.738 212.675 1.00 44.87  ? 405 ALA D C     1 
ATOM   4132  O O     . ALA B 2 423 ? 120.054 158.794 213.142 1.00 44.87  ? 405 ALA D O     1 
ATOM   4133  C CB    . ALA B 2 423 ? 118.419 157.744 210.468 1.00 44.87  ? 405 ALA D CB    1 
ATOM   4134  N N     . ALA B 2 424 ? 119.049 156.807 213.446 1.00 48.27  ? 406 ALA D N     1 
ATOM   4135  C CA    . ALA B 2 424 ? 118.897 157.012 214.879 1.00 48.27  ? 406 ALA D CA    1 
ATOM   4136  C C     . ALA B 2 424 ? 120.222 156.885 215.610 1.00 48.27  ? 406 ALA D C     1 
ATOM   4137  O O     . ALA B 2 424 ? 120.430 157.565 216.619 1.00 48.27  ? 406 ALA D O     1 
ATOM   4138  C CB    . ALA B 2 424 ? 117.880 156.019 215.431 1.00 48.27  ? 406 ALA D CB    1 
ATOM   4139  N N     . ALA B 2 425 ? 121.132 156.038 215.120 1.00 50.32  ? 407 ALA D N     1 
ATOM   4140  C CA    . ALA B 2 425 ? 122.472 156.000 215.692 1.00 50.32  ? 407 ALA D CA    1 
ATOM   4141  C C     . ALA B 2 425 ? 123.180 157.333 215.501 1.00 50.32  ? 407 ALA D C     1 
ATOM   4142  O O     . ALA B 2 425 ? 123.823 157.843 216.426 1.00 50.32  ? 407 ALA D O     1 
ATOM   4143  C CB    . ALA B 2 425 ? 123.280 154.867 215.062 1.00 50.32  ? 407 ALA D CB    1 
ATOM   4144  N N     . LEU B 2 426 ? 123.046 157.931 214.315 1.00 45.45  ? 408 LEU D N     1 
ATOM   4145  C CA    . LEU B 2 426 ? 123.674 159.232 214.089 1.00 45.45  ? 408 LEU D CA    1 
ATOM   4146  C C     . LEU B 2 426 ? 122.997 160.327 214.906 1.00 45.45  ? 408 LEU D C     1 
ATOM   4147  O O     . LEU B 2 426 ? 123.666 161.250 215.386 1.00 45.45  ? 408 LEU D O     1 
ATOM   4148  C CB    . LEU B 2 426 ? 123.656 159.588 212.604 1.00 45.45  ? 408 LEU D CB    1 
ATOM   4149  C CG    . LEU B 2 426 ? 124.886 159.145 211.799 1.00 45.45  ? 408 LEU D CG    1 
ATOM   4150  C CD1   . LEU B 2 426 ? 126.052 160.104 211.974 1.00 45.45  ? 408 LEU D CD1   1 
ATOM   4151  C CD2   . LEU B 2 426 ? 125.322 157.712 212.116 1.00 45.45  ? 408 LEU D CD2   1 
ATOM   4152  N N     . SER B 2 427 ? 121.675 160.247 215.073 1.00 47.12  ? 409 SER D N     1 
ATOM   4153  C CA    . SER B 2 427 ? 120.979 161.222 215.908 1.00 47.12  ? 409 SER D CA    1 
ATOM   4154  C C     . SER B 2 427 ? 121.424 161.119 217.363 1.00 47.12  ? 409 SER D C     1 
ATOM   4155  O O     . SER B 2 427 ? 121.621 162.139 218.033 1.00 47.12  ? 409 SER D O     1 
ATOM   4156  C CB    . SER B 2 427 ? 119.469 161.026 215.796 1.00 47.12  ? 409 SER D CB    1 
ATOM   4157  O OG    . SER B 2 427 ? 118.773 161.962 216.599 1.00 47.12  ? 409 SER D OG    1 
ATOM   4158  N N     . CYS B 2 428 ? 121.594 159.895 217.867 1.00 54.32  ? 410 CYS D N     1 
ATOM   4159  C CA    . CYS B 2 428 ? 122.080 159.714 219.230 1.00 54.32  ? 410 CYS D CA    1 
ATOM   4160  C C     . CYS B 2 428 ? 123.518 160.194 219.372 1.00 54.32  ? 410 CYS D C     1 
ATOM   4161  O O     . CYS B 2 428 ? 123.896 160.733 220.418 1.00 54.32  ? 410 CYS D O     1 
ATOM   4162  C CB    . CYS B 2 428 ? 121.967 158.246 219.635 1.00 54.32  ? 410 CYS D CB    1 
ATOM   4163  S SG    . CYS B 2 428 ? 122.611 157.879 221.282 1.00 54.32  ? 410 CYS D SG    1 
ATOM   4164  N N     . GLN B 2 429 ? 124.339 159.987 218.339 1.00 50.67  ? 411 GLN D N     1 
ATOM   4165  C CA    . GLN B 2 429 ? 125.707 160.495 218.368 1.00 50.67  ? 411 GLN D CA    1 
ATOM   4166  C C     . GLN B 2 429 ? 125.721 162.019 218.422 1.00 50.67  ? 411 GLN D C     1 
ATOM   4167  O O     . GLN B 2 429 ? 126.515 162.614 219.160 1.00 50.67  ? 411 GLN D O     1 
ATOM   4168  C CB    . GLN B 2 429 ? 126.471 159.982 217.145 1.00 50.67  ? 411 GLN D CB    1 
ATOM   4169  C CG    . GLN B 2 429 ? 127.986 160.177 217.188 1.00 50.67  ? 411 GLN D CG    1 
ATOM   4170  C CD    . GLN B 2 429 ? 128.582 160.356 215.806 1.00 50.67  ? 411 GLN D CD    1 
ATOM   4171  O OE1   . GLN B 2 429 ? 128.737 159.391 215.058 1.00 50.67  ? 411 GLN D OE1   1 
ATOM   4172  N NE2   . GLN B 2 429 ? 128.913 161.594 215.458 1.00 50.67  ? 411 GLN D NE2   1 
ATOM   4173  N N     . LYS B 2 430 ? 124.851 162.669 217.644 1.00 46.61  ? 412 LYS D N     1 
ATOM   4174  C CA    . LYS B 2 430 ? 124.732 164.123 217.727 1.00 46.61  ? 412 LYS D CA    1 
ATOM   4175  C C     . LYS B 2 430 ? 124.203 164.565 219.085 1.00 46.61  ? 412 LYS D C     1 
ATOM   4176  O O     . LYS B 2 430 ? 124.558 165.647 219.566 1.00 46.61  ? 412 LYS D O     1 
ATOM   4177  C CB    . LYS B 2 430 ? 123.826 164.651 216.615 1.00 46.61  ? 412 LYS D CB    1 
ATOM   4178  C CG    . LYS B 2 430 ? 124.559 164.956 215.323 1.00 46.61  ? 412 LYS D CG    1 
ATOM   4179  C CD    . LYS B 2 430 ? 125.226 166.322 215.376 1.00 46.61  ? 412 LYS D CD    1 
ATOM   4180  C CE    . LYS B 2 430 ? 124.276 167.425 214.947 1.00 46.61  ? 412 LYS D CE    1 
ATOM   4181  N NZ    . LYS B 2 430 ? 124.274 167.611 213.470 1.00 46.61  ? 412 LYS D NZ    1 
ATOM   4182  N N     . ARG B 2 431 ? 123.357 163.749 219.712 1.00 57.19  ? 413 ARG D N     1 
ATOM   4183  C CA    . ARG B 2 431 ? 122.890 164.000 221.070 1.00 57.19  ? 413 ARG D CA    1 
ATOM   4184  C C     . ARG B 2 431 ? 123.937 163.694 222.139 1.00 57.19  ? 413 ARG D C     1 
ATOM   4185  O O     . ARG B 2 431 ? 123.669 163.940 223.320 1.00 57.19  ? 413 ARG D O     1 
ATOM   4186  C CB    . ARG B 2 431 ? 121.631 163.168 221.334 1.00 57.19  ? 413 ARG D CB    1 
ATOM   4187  C CG    . ARG B 2 431 ? 120.753 163.676 222.468 1.00 57.19  ? 413 ARG D CG    1 
ATOM   4188  C CD    . ARG B 2 431 ? 119.381 163.020 222.443 1.00 57.19  ? 413 ARG D CD    1 
ATOM   4189  N NE    . ARG B 2 431 ? 119.466 161.562 222.441 1.00 57.19  ? 413 ARG D NE    1 
ATOM   4190  C CZ    . ARG B 2 431 ? 119.696 160.796 223.503 1.00 57.19  ? 413 ARG D CZ    1 
ATOM   4191  N NH1   . ARG B 2 431 ? 119.897 161.307 224.710 1.00 57.19  ? 413 ARG D NH1   1 
ATOM   4192  N NH2   . ARG B 2 431 ? 119.731 159.476 223.350 1.00 57.19  ? 413 ARG D NH2   1 
ATOM   4193  N N     . LYS B 2 432 ? 125.103 163.149 221.767 1.00 60.44  ? 414 LYS D N     1 
ATOM   4194  C CA    . LYS B 2 432 ? 126.183 162.822 222.702 1.00 60.44  ? 414 LYS D CA    1 
ATOM   4195  C C     . LYS B 2 432 ? 125.756 161.769 223.725 1.00 60.44  ? 414 LYS D C     1 
ATOM   4196  O O     . LYS B 2 432 ? 126.266 161.740 224.848 1.00 60.44  ? 414 LYS D O     1 
ATOM   4197  C CB    . LYS B 2 432 ? 126.718 164.074 223.416 1.00 60.44  ? 414 LYS D CB    1 
ATOM   4198  C CG    . LYS B 2 432 ? 127.256 165.169 222.495 1.00 60.44  ? 414 LYS D CG    1 
ATOM   4199  C CD    . LYS B 2 432 ? 128.643 164.832 221.972 1.00 60.44  ? 414 LYS D CD    1 
ATOM   4200  C CE    . LYS B 2 432 ? 129.104 165.841 220.934 1.00 60.44  ? 414 LYS D CE    1 
ATOM   4201  N NZ    . LYS B 2 432 ? 129.054 165.286 219.553 1.00 60.44  ? 414 LYS D NZ    1 
ATOM   4202  N N     . GLY B 2 433 ? 124.821 160.891 223.343 1.00 61.91  ? 415 GLY D N     1 
ATOM   4203  C CA    . GLY B 2 433 ? 124.425 159.777 224.177 1.00 61.91  ? 415 GLY D CA    1 
ATOM   4204  C C     . GLY B 2 433 ? 125.298 158.557 223.946 1.00 61.91  ? 415 GLY D C     1 
ATOM   4205  O O     . GLY B 2 433 ? 126.188 158.544 223.096 1.00 61.91  ? 415 GLY D O     1 
ATOM   4206  N N     . LYS B 2 434 ? 125.025 157.519 224.743 1.00 64.43  ? 416 LYS D N     1 
ATOM   4207  C CA    . LYS B 2 434 ? 125.640 156.203 224.604 1.00 64.43  ? 416 LYS D CA    1 
ATOM   4208  C C     . LYS B 2 434 ? 124.641 155.103 224.264 1.00 64.43  ? 416 LYS D C     1 
ATOM   4209  O O     . LYS B 2 434 ? 125.048 153.942 224.134 1.00 64.43  ? 416 LYS D O     1 
ATOM   4210  C CB    . LYS B 2 434 ? 126.380 155.830 225.900 1.00 64.43  ? 416 LYS D CB    1 
ATOM   4211  C CG    . LYS B 2 434 ? 127.593 156.705 226.255 1.00 64.43  ? 416 LYS D CG    1 
ATOM   4212  C CD    . LYS B 2 434 ? 128.674 156.729 225.171 1.00 64.43  ? 416 LYS D CD    1 
ATOM   4213  C CE    . LYS B 2 434 ? 129.964 157.376 225.655 1.00 64.43  ? 416 LYS D CE    1 
ATOM   4214  N NZ    . LYS B 2 434 ? 129.860 158.861 225.689 1.00 64.43  ? 416 LYS D NZ    1 
ATOM   4215  N N     . VAL B 2 435 ? 123.356 155.420 224.114 1.00 60.67  ? 417 VAL D N     1 
ATOM   4216  C CA    . VAL B 2 435 ? 122.347 154.439 223.732 1.00 60.67  ? 417 VAL D CA    1 
ATOM   4217  C C     . VAL B 2 435 ? 121.216 155.190 223.047 1.00 60.67  ? 417 VAL D C     1 
ATOM   4218  O O     . VAL B 2 435 ? 120.878 156.313 223.433 1.00 60.67  ? 417 VAL D O     1 
ATOM   4219  C CB    . VAL B 2 435 ? 121.853 153.633 224.957 1.00 60.67  ? 417 VAL D CB    1 
ATOM   4220  C CG1   . VAL B 2 435 ? 120.996 154.499 225.883 1.00 60.67  ? 417 VAL D CG1   1 
ATOM   4221  C CG2   . VAL B 2 435 ? 121.098 152.374 224.526 1.00 60.67  ? 417 VAL D CG2   1 
ATOM   4222  N N     . VAL B 2 436 ? 120.637 154.566 222.026 1.00 57.25  ? 418 VAL D N     1 
ATOM   4223  C CA    . VAL B 2 436 ? 119.570 155.171 221.235 1.00 57.25  ? 418 VAL D CA    1 
ATOM   4224  C C     . VAL B 2 436 ? 118.239 154.765 221.853 1.00 57.25  ? 418 VAL D C     1 
ATOM   4225  O O     . VAL B 2 436 ? 117.958 153.571 222.009 1.00 57.25  ? 418 VAL D O     1 
ATOM   4226  C CB    . VAL B 2 436 ? 119.653 154.743 219.762 1.00 57.25  ? 418 VAL D CB    1 
ATOM   4227  C CG1   . VAL B 2 436 ? 118.859 155.692 218.889 1.00 57.25  ? 418 VAL D CG1   1 
ATOM   4228  C CG2   . VAL B 2 436 ? 121.110 154.666 219.290 1.00 57.25  ? 418 VAL D CG2   1 
ATOM   4229  N N     . GLU B 2 437 ? 117.419 155.759 222.189 1.00 59.72  ? 419 GLU D N     1 
ATOM   4230  C CA    . GLU B 2 437 ? 116.183 155.596 222.942 1.00 59.72  ? 419 GLU D CA    1 
ATOM   4231  C C     . GLU B 2 437 ? 114.982 155.970 222.076 1.00 59.72  ? 419 GLU D C     1 
ATOM   4232  O O     . GLU B 2 437 ? 115.112 156.286 220.890 1.00 59.72  ? 419 GLU D O     1 
ATOM   4233  C CB    . GLU B 2 437 ? 116.244 156.434 224.223 1.00 59.72  ? 419 GLU D CB    1 
ATOM   4234  C CG    . GLU B 2 437 ? 116.163 157.935 224.001 1.00 59.72  ? 419 GLU D CG    1 
ATOM   4235  C CD    . GLU B 2 437 ? 116.958 158.719 225.023 1.00 59.72  ? 419 GLU D CD    1 
ATOM   4236  O OE1   . GLU B 2 437 ? 118.202 158.614 225.017 1.00 59.72  ? 419 GLU D OE1   1 
ATOM   4237  O OE2   . GLU B 2 437 ? 116.339 159.445 225.829 1.00 59.72  ? 419 GLU D OE2   1 
ATOM   4238  N N     . VAL B 2 438 ? 113.798 155.929 222.694 1.00 62.76  ? 420 VAL D N     1 
ATOM   4239  C CA    . VAL B 2 438 ? 112.542 156.142 221.975 1.00 62.76  ? 420 VAL D CA    1 
ATOM   4240  C C     . VAL B 2 438 ? 112.449 157.562 221.424 1.00 62.76  ? 420 VAL D C     1 
ATOM   4241  O O     . VAL B 2 438 ? 111.778 157.796 220.413 1.00 62.76  ? 420 VAL D O     1 
ATOM   4242  C CB    . VAL B 2 438 ? 111.355 155.805 222.905 1.00 62.76  ? 420 VAL D CB    1 
ATOM   4243  C CG1   . VAL B 2 438 ? 110.012 156.273 222.312 1.00 62.76  ? 420 VAL D CG1   1 
ATOM   4244  C CG2   . VAL B 2 438 ? 111.328 154.301 223.197 1.00 62.76  ? 420 VAL D CG2   1 
ATOM   4245  N N     . GLU B 2 439 ? 113.091 158.529 222.084 1.00 62.40  ? 421 GLU D N     1 
ATOM   4246  C CA    . GLU B 2 439 ? 113.121 159.897 221.570 1.00 62.40  ? 421 GLU D CA    1 
ATOM   4247  C C     . GLU B 2 439 ? 113.817 159.956 220.212 1.00 62.40  ? 421 GLU D C     1 
ATOM   4248  O O     . GLU B 2 439 ? 113.344 160.635 219.291 1.00 62.40  ? 421 GLU D O     1 
ATOM   4249  C CB    . GLU B 2 439 ? 113.799 160.808 222.608 1.00 62.40  ? 421 GLU D CB    1 
ATOM   4250  C CG    . GLU B 2 439 ? 114.324 162.189 222.157 1.00 62.40  ? 421 GLU D CG    1 
ATOM   4251  C CD    . GLU B 2 439 ? 115.040 162.914 223.282 1.00 62.40  ? 421 GLU D CD    1 
ATOM   4252  O OE1   . GLU B 2 439 ? 115.919 162.299 223.922 1.00 62.40  ? 421 GLU D OE1   1 
ATOM   4253  O OE2   . GLU B 2 439 ? 114.724 164.097 223.527 1.00 62.40  ? 421 GLU D OE2   1 
ATOM   4254  N N     . ASP B 2 440 ? 114.940 159.250 220.069 1.00 56.21  ? 422 ASP D N     1 
ATOM   4255  C CA    . ASP B 2 440 ? 115.658 159.256 218.799 1.00 56.21  ? 422 ASP D CA    1 
ATOM   4256  C C     . ASP B 2 440 ? 114.851 158.571 217.703 1.00 56.21  ? 422 ASP D C     1 
ATOM   4257  O O     . ASP B 2 440 ? 114.833 159.037 216.556 1.00 56.21  ? 422 ASP D O     1 
ATOM   4258  C CB    . ASP B 2 440 ? 117.020 158.584 218.961 1.00 56.21  ? 422 ASP D CB    1 
ATOM   4259  C CG    . ASP B 2 440 ? 118.063 159.514 219.553 1.00 56.21  ? 422 ASP D CG    1 
ATOM   4260  O OD1   . ASP B 2 440 ? 118.248 160.627 219.018 1.00 56.21  ? 422 ASP D OD1   1 
ATOM   4261  O OD2   . ASP B 2 440 ? 118.701 159.133 220.556 1.00 56.21  ? 422 ASP D OD2   1 
ATOM   4262  N N     . ILE B 2 441 ? 114.173 157.470 218.035 1.00 55.09  ? 423 ILE D N     1 
ATOM   4263  C CA    . ILE B 2 441 ? 113.337 156.793 217.049 1.00 55.09  ? 423 ILE D CA    1 
ATOM   4264  C C     . ILE B 2 441 ? 112.162 157.678 216.655 1.00 55.09  ? 423 ILE D C     1 
ATOM   4265  O O     . ILE B 2 441 ? 111.757 157.703 215.490 1.00 55.09  ? 423 ILE D O     1 
ATOM   4266  C CB    . ILE B 2 441 ? 112.854 155.428 217.582 1.00 55.09  ? 423 ILE D CB    1 
ATOM   4267  C CG1   . ILE B 2 441 ? 114.026 154.519 218.011 1.00 55.09  ? 423 ILE D CG1   1 
ATOM   4268  C CG2   . ILE B 2 441 ? 111.962 154.743 216.541 1.00 55.09  ? 423 ILE D CG2   1 
ATOM   4269  C CD1   . ILE B 2 441 ? 115.081 154.243 216.952 1.00 55.09  ? 423 ILE D CD1   1 
ATOM   4270  N N     . GLN B 2 442 ? 111.604 158.419 217.618 1.00 60.61  ? 424 GLN D N     1 
ATOM   4271  C CA    . GLN B 2 442 ? 110.526 159.361 217.329 1.00 60.61  ? 424 GLN D CA    1 
ATOM   4272  C C     . GLN B 2 442 ? 110.996 160.436 216.358 1.00 60.61  ? 424 GLN D C     1 
ATOM   4273  O O     . GLN B 2 442 ? 110.317 160.734 215.366 1.00 60.61  ? 424 GLN D O     1 
ATOM   4274  C CB    . GLN B 2 442 ? 110.035 159.984 218.643 1.00 60.61  ? 424 GLN D CB    1 
ATOM   4275  C CG    . GLN B 2 442 ? 108.856 160.996 218.560 1.00 60.61  ? 424 GLN D CG    1 
ATOM   4276  C CD    . GLN B 2 442 ? 109.012 162.193 219.496 1.00 60.61  ? 424 GLN D CD    1 
ATOM   4277  O OE1   . GLN B 2 442 ? 110.102 162.744 219.655 1.00 60.61  ? 424 GLN D OE1   1 
ATOM   4278  N NE2   . GLN B 2 442 ? 107.910 162.600 220.117 1.00 60.61  ? 424 GLN D NE2   1 
ATOM   4279  N N     . ARG B 2 443 ? 112.171 161.013 216.627 1.00 48.68  ? 425 ARG D N     1 
ATOM   4280  C CA    . ARG B 2 443 ? 112.721 162.055 215.764 1.00 48.68  ? 425 ARG D CA    1 
ATOM   4281  C C     . ARG B 2 443 ? 112.973 161.525 214.358 1.00 48.68  ? 425 ARG D C     1 
ATOM   4282  O O     . ARG B 2 443 ? 112.589 162.154 213.366 1.00 48.68  ? 425 ARG D O     1 
ATOM   4283  C CB    . ARG B 2 443 ? 114.015 162.595 216.382 1.00 48.68  ? 425 ARG D CB    1 
ATOM   4284  C CG    . ARG B 2 443 ? 114.652 163.795 215.674 1.00 48.68  ? 425 ARG D CG    1 
ATOM   4285  C CD    . ARG B 2 443 ? 116.025 164.092 216.251 1.00 48.68  ? 425 ARG D CD    1 
ATOM   4286  N NE    . ARG B 2 443 ? 116.684 165.190 215.546 1.00 48.68  ? 425 ARG D NE    1 
ATOM   4287  C CZ    . ARG B 2 443 ? 117.997 165.392 215.470 1.00 48.68  ? 425 ARG D CZ    1 
ATOM   4288  N NH1   . ARG B 2 443 ? 118.870 164.608 216.088 1.00 48.68  ? 425 ARG D NH1   1 
ATOM   4289  N NH2   . ARG B 2 443 ? 118.450 166.420 214.759 1.00 48.68  ? 425 ARG D NH2   1 
ATOM   4290  N N     . VAL B 2 444 ? 113.593 160.352 214.256 1.00 45.00  ? 426 VAL D N     1 
ATOM   4291  C CA    . VAL B 2 444 ? 113.977 159.839 212.946 1.00 45.00  ? 426 VAL D CA    1 
ATOM   4292  C C     . VAL B 2 444 ? 112.749 159.385 212.163 1.00 45.00  ? 426 VAL D C     1 
ATOM   4293  O O     . VAL B 2 444 ? 112.688 159.553 210.939 1.00 45.00  ? 426 VAL D O     1 
ATOM   4294  C CB    . VAL B 2 444 ? 115.032 158.728 213.120 1.00 45.00  ? 426 VAL D CB    1 
ATOM   4295  C CG1   . VAL B 2 444 ? 115.123 157.804 211.904 1.00 45.00  ? 426 VAL D CG1   1 
ATOM   4296  C CG2   . VAL B 2 444 ? 116.385 159.366 213.406 1.00 45.00  ? 426 VAL D CG2   1 
ATOM   4297  N N     . TYR B 2 445 ? 111.759 158.793 212.837 1.00 50.81  ? 427 TYR D N     1 
ATOM   4298  C CA    . TYR B 2 445 ? 110.523 158.431 212.153 1.00 50.81  ? 427 TYR D CA    1 
ATOM   4299  C C     . TYR B 2 445 ? 109.776 159.668 211.678 1.00 50.81  ? 427 TYR D C     1 
ATOM   4300  O O     . TYR B 2 445 ? 109.168 159.656 210.602 1.00 50.81  ? 427 TYR D O     1 
ATOM   4301  C CB    . TYR B 2 445 ? 109.637 157.591 213.072 1.00 50.81  ? 427 TYR D CB    1 
ATOM   4302  C CG    . TYR B 2 445 ? 108.346 157.149 212.422 1.00 50.81  ? 427 TYR D CG    1 
ATOM   4303  C CD1   . TYR B 2 445 ? 108.319 156.071 211.550 1.00 50.81  ? 427 TYR D CD1   1 
ATOM   4304  C CD2   . TYR B 2 445 ? 107.153 157.808 212.685 1.00 50.81  ? 427 TYR D CD2   1 
ATOM   4305  C CE1   . TYR B 2 445 ? 107.141 155.666 210.952 1.00 50.81  ? 427 TYR D CE1   1 
ATOM   4306  C CE2   . TYR B 2 445 ? 105.972 157.410 212.092 1.00 50.81  ? 427 TYR D CE2   1 
ATOM   4307  C CZ    . TYR B 2 445 ? 105.972 156.339 211.227 1.00 50.81  ? 427 TYR D CZ    1 
ATOM   4308  O OH    . TYR B 2 445 ? 104.797 155.938 210.637 1.00 50.81  ? 427 TYR D OH    1 
ATOM   4309  N N     . ARG B 2 446 ? 109.796 160.742 212.471 1.00 48.45  ? 428 ARG D N     1 
ATOM   4310  C CA    . ARG B 2 446 ? 109.167 161.983 212.039 1.00 48.45  ? 428 ARG D CA    1 
ATOM   4311  C C     . ARG B 2 446 ? 109.884 162.564 210.826 1.00 48.45  ? 428 ARG D C     1 
ATOM   4312  O O     . ARG B 2 446 ? 109.237 163.055 209.894 1.00 48.45  ? 428 ARG D O     1 
ATOM   4313  C CB    . ARG B 2 446 ? 109.154 162.973 213.207 1.00 48.45  ? 428 ARG D CB    1 
ATOM   4314  C CG    . ARG B 2 446 ? 108.464 164.319 212.957 1.00 48.45  ? 428 ARG D CG    1 
ATOM   4315  C CD    . ARG B 2 446 ? 108.681 165.268 214.125 1.00 48.45  ? 428 ARG D CD    1 
ATOM   4316  N NE    . ARG B 2 446 ? 110.070 165.719 214.208 1.00 48.45  ? 428 ARG D NE    1 
ATOM   4317  C CZ    . ARG B 2 446 ? 110.492 166.873 214.714 1.00 48.45  ? 428 ARG D CZ    1 
ATOM   4318  N NH1   . ARG B 2 446 ? 109.666 167.743 215.279 1.00 48.45  ? 428 ARG D NH1   1 
ATOM   4319  N NH2   . ARG B 2 446 ? 111.790 167.160 214.666 1.00 48.45  ? 428 ARG D NH2   1 
ATOM   4320  N N     . LEU B 2 447 ? 111.218 162.511 210.813 1.00 39.19  ? 429 LEU D N     1 
ATOM   4321  C CA    . LEU B 2 447 ? 111.981 163.166 209.755 1.00 39.19  ? 429 LEU D CA    1 
ATOM   4322  C C     . LEU B 2 447 ? 111.960 162.360 208.460 1.00 39.19  ? 429 LEU D C     1 
ATOM   4323  O O     . LEU B 2 447 ? 111.437 162.823 207.442 1.00 39.19  ? 429 LEU D O     1 
ATOM   4324  C CB    . LEU B 2 447 ? 113.424 163.395 210.215 1.00 39.19  ? 429 LEU D CB    1 
ATOM   4325  C CG    . LEU B 2 447 ? 113.685 164.452 211.294 1.00 39.19  ? 429 LEU D CG    1 
ATOM   4326  C CD1   . LEU B 2 447 ? 115.144 164.415 211.706 1.00 39.19  ? 429 LEU D CD1   1 
ATOM   4327  C CD2   . LEU B 2 447 ? 113.312 165.847 210.825 1.00 39.19  ? 429 LEU D CD2   1 
ATOM   4328  N N     . PHE B 2 448 ? 112.516 161.148 208.484 1.00 36.77  ? 430 PHE D N     1 
ATOM   4329  C CA    . PHE B 2 448 ? 112.662 160.329 207.282 1.00 36.77  ? 430 PHE D CA    1 
ATOM   4330  C C     . PHE B 2 448 ? 111.388 159.523 207.068 1.00 36.77  ? 430 PHE D C     1 
ATOM   4331  O O     . PHE B 2 448 ? 111.054 158.647 207.872 1.00 36.77  ? 430 PHE D O     1 
ATOM   4332  C CB    . PHE B 2 448 ? 113.870 159.401 207.392 1.00 36.77  ? 430 PHE D CB    1 
ATOM   4333  C CG    . PHE B 2 448 ? 115.189 160.115 207.541 1.00 36.77  ? 430 PHE D CG    1 
ATOM   4334  C CD1   . PHE B 2 448 ? 115.575 161.105 206.654 1.00 36.77  ? 430 PHE D CD1   1 
ATOM   4335  C CD2   . PHE B 2 448 ? 116.052 159.775 208.563 1.00 36.77  ? 430 PHE D CD2   1 
ATOM   4336  C CE1   . PHE B 2 448 ? 116.776 161.746 206.796 1.00 36.77  ? 430 PHE D CE1   1 
ATOM   4337  C CE2   . PHE B 2 448 ? 117.260 160.415 208.705 1.00 36.77  ? 430 PHE D CE2   1 
ATOM   4338  C CZ    . PHE B 2 448 ? 117.623 161.401 207.820 1.00 36.77  ? 430 PHE D CZ    1 
ATOM   4339  N N     . LEU B 2 449 ? 110.692 159.806 205.973 1.00 40.68  ? 431 LEU D N     1 
ATOM   4340  C CA    . LEU B 2 449 ? 109.455 159.118 205.649 1.00 40.68  ? 431 LEU D CA    1 
ATOM   4341  C C     . LEU B 2 449 ? 109.745 157.765 205.008 1.00 40.68  ? 431 LEU D C     1 
ATOM   4342  O O     . LEU B 2 449 ? 110.826 157.523 204.467 1.00 40.68  ? 431 LEU D O     1 
ATOM   4343  C CB    . LEU B 2 449 ? 108.602 159.961 204.701 1.00 40.68  ? 431 LEU D CB    1 
ATOM   4344  C CG    . LEU B 2 449 ? 107.716 161.027 205.345 1.00 40.68  ? 431 LEU D CG    1 
ATOM   4345  C CD1   . LEU B 2 449 ? 108.548 162.167 205.910 1.00 40.68  ? 431 LEU D CD1   1 
ATOM   4346  C CD2   . LEU B 2 449 ? 106.713 161.543 204.329 1.00 40.68  ? 431 LEU D CD2   1 
ATOM   4347  N N     . ASP B 2 450 ? 108.757 156.875 205.088 1.00 45.77  ? 432 ASP D N     1 
ATOM   4348  C CA    . ASP B 2 450 ? 108.751 155.638 204.325 1.00 45.77  ? 432 ASP D CA    1 
ATOM   4349  C C     . ASP B 2 450 ? 108.094 155.901 202.973 1.00 45.77  ? 432 ASP D C     1 
ATOM   4350  O O     . ASP B 2 450 ? 107.647 157.012 202.681 1.00 45.77  ? 432 ASP D O     1 
ATOM   4351  C CB    . ASP B 2 450 ? 108.046 154.525 205.104 1.00 45.77  ? 432 ASP D CB    1 
ATOM   4352  C CG    . ASP B 2 450 ? 106.568 154.795 205.324 1.00 45.77  ? 432 ASP D CG    1 
ATOM   4353  O OD1   . ASP B 2 450 ? 105.776 154.648 204.371 1.00 45.77  ? 432 ASP D OD1   1 
ATOM   4354  O OD2   . ASP B 2 450 ? 106.194 155.152 206.461 1.00 45.77  ? 432 ASP D OD2   1 
ATOM   4355  N N     . VAL B 2 451 ? 108.034 154.868 202.131 1.00 45.21  ? 433 VAL D N     1 
ATOM   4356  C CA    . VAL B 2 451 ? 107.465 155.049 200.799 1.00 45.21  ? 433 VAL D CA    1 
ATOM   4357  C C     . VAL B 2 451 ? 105.960 155.289 200.873 1.00 45.21  ? 433 VAL D C     1 
ATOM   4358  O O     . VAL B 2 451 ? 105.411 156.047 200.063 1.00 45.21  ? 433 VAL D O     1 
ATOM   4359  C CB    . VAL B 2 451 ? 107.820 153.846 199.900 1.00 45.21  ? 433 VAL D CB    1 
ATOM   4360  C CG1   . VAL B 2 451 ? 107.022 152.602 200.280 1.00 45.21  ? 433 VAL D CG1   1 
ATOM   4361  C CG2   . VAL B 2 451 ? 107.609 154.193 198.432 1.00 45.21  ? 433 VAL D CG2   1 
ATOM   4362  N N     . ARG B 2 452 ? 105.274 154.680 201.847 1.00 52.75  ? 434 ARG D N     1 
ATOM   4363  C CA    . ARG B 2 452 ? 103.819 154.799 201.921 1.00 52.75  ? 434 ARG D CA    1 
ATOM   4364  C C     . ARG B 2 452 ? 103.397 156.224 202.255 1.00 52.75  ? 434 ARG D C     1 
ATOM   4365  O O     . ARG B 2 452 ? 102.519 156.790 201.596 1.00 52.75  ? 434 ARG D O     1 
ATOM   4366  C CB    . ARG B 2 452 ? 103.247 153.824 202.958 1.00 52.75  ? 434 ARG D CB    1 
ATOM   4367  C CG    . ARG B 2 452 ? 101.953 153.122 202.528 1.00 52.75  ? 434 ARG D CG    1 
ATOM   4368  C CD    . ARG B 2 452 ? 102.148 152.044 201.448 1.00 52.75  ? 434 ARG D CD    1 
ATOM   4369  N NE    . ARG B 2 452 ? 103.148 151.035 201.789 1.00 52.75  ? 434 ARG D NE    1 
ATOM   4370  C CZ    . ARG B 2 452 ? 103.037 150.127 202.753 1.00 52.75  ? 434 ARG D CZ    1 
ATOM   4371  N NH1   . ARG B 2 452 ? 101.945 150.019 203.498 1.00 52.75  ? 434 ARG D NH1   1 
ATOM   4372  N NH2   . ARG B 2 452 ? 104.048 149.293 202.973 1.00 52.75  ? 434 ARG D NH2   1 
ATOM   4373  N N     . ARG B 2 453 ? 104.025 156.830 203.266 1.00 49.20  ? 435 ARG D N     1 
ATOM   4374  C CA    . ARG B 2 453 ? 103.610 158.164 203.687 1.00 49.20  ? 435 ARG D CA    1 
ATOM   4375  C C     . ARG B 2 453 ? 103.981 159.221 202.654 1.00 49.20  ? 435 ARG D C     1 
ATOM   4376  O O     . ARG B 2 453 ? 103.200 160.144 202.403 1.00 49.20  ? 435 ARG D O     1 
ATOM   4377  C CB    . ARG B 2 453 ? 104.213 158.500 205.050 1.00 49.20  ? 435 ARG D CB    1 
ATOM   4378  C CG    . ARG B 2 453 ? 103.542 157.758 206.190 1.00 49.20  ? 435 ARG D CG    1 
ATOM   4379  C CD    . ARG B 2 453 ? 104.128 158.106 207.549 1.00 49.20  ? 435 ARG D CD    1 
ATOM   4380  N NE    . ARG B 2 453 ? 105.507 157.647 207.706 1.00 49.20  ? 435 ARG D NE    1 
ATOM   4381  C CZ    . ARG B 2 453 ? 106.470 158.252 208.398 1.00 49.20  ? 435 ARG D CZ    1 
ATOM   4382  N NH1   . ARG B 2 453 ? 106.265 159.381 209.062 1.00 49.20  ? 435 ARG D NH1   1 
ATOM   4383  N NH2   . ARG B 2 453 ? 107.675 157.693 208.445 1.00 49.20  ? 435 ARG D NH2   1 
ATOM   4384  N N     . SER B 2 454 ? 105.162 159.109 202.041 1.00 42.64  ? 436 SER D N     1 
ATOM   4385  C CA    . SER B 2 454 ? 105.542 160.059 200.999 1.00 42.64  ? 436 SER D CA    1 
ATOM   4386  C C     . SER B 2 454 ? 104.641 159.929 199.777 1.00 42.64  ? 436 SER D C     1 
ATOM   4387  O O     . SER B 2 454 ? 104.231 160.941 199.186 1.00 42.64  ? 436 SER D O     1 
ATOM   4388  C CB    . SER B 2 454 ? 107.001 159.847 200.607 1.00 42.64  ? 436 SER D CB    1 
ATOM   4389  O OG    . SER B 2 454 ? 107.242 158.488 200.293 1.00 42.64  ? 436 SER D OG    1 
ATOM   4390  N N     . MET B 2 455 ? 104.327 158.688 199.387 1.00 49.30  ? 437 MET D N     1 
ATOM   4391  C CA    . MET B 2 455 ? 103.421 158.462 198.267 1.00 49.30  ? 437 MET D CA    1 
ATOM   4392  C C     . MET B 2 455 ? 102.042 159.031 198.571 1.00 49.30  ? 437 MET D C     1 
ATOM   4393  O O     . MET B 2 455 ? 101.425 159.665 197.711 1.00 49.30  ? 437 MET D O     1 
ATOM   4394  C CB    . MET B 2 455 ? 103.354 156.961 197.967 1.00 49.30  ? 437 MET D CB    1 
ATOM   4395  C CG    . MET B 2 455 ? 102.448 156.513 196.811 1.00 49.30  ? 437 MET D CG    1 
ATOM   4396  S SD    . MET B 2 455 ? 102.245 154.723 196.815 1.00 49.30  ? 437 MET D SD    1 
ATOM   4397  C CE    . MET B 2 455 ? 100.700 154.568 197.705 1.00 49.30  ? 437 MET D CE    1 
ATOM   4398  N N     . GLN B 2 456 ? 101.557 158.834 199.800 1.00 53.69  ? 438 GLN D N     1 
ATOM   4399  C CA    . GLN B 2 456 ? 100.273 159.398 200.202 1.00 53.69  ? 438 GLN D CA    1 
ATOM   4400  C C     . GLN B 2 456 ? 100.302 160.920 200.160 1.00 53.69  ? 438 GLN D C     1 
ATOM   4401  O O     . GLN B 2 456 ? 99.345  161.550 199.702 1.00 53.69  ? 438 GLN D O     1 
ATOM   4402  C CB    . GLN B 2 456 ? 99.924  158.913 201.607 1.00 53.69  ? 438 GLN D CB    1 
ATOM   4403  C CG    . GLN B 2 456 ? 98.499  159.205 202.079 1.00 53.69  ? 438 GLN D CG    1 
ATOM   4404  C CD    . GLN B 2 456 ? 98.431  159.526 203.559 1.00 53.69  ? 438 GLN D CD    1 
ATOM   4405  O OE1   . GLN B 2 456 ? 99.246  159.054 204.349 1.00 53.69  ? 438 GLN D OE1   1 
ATOM   4406  N NE2   . GLN B 2 456 ? 97.434  160.311 203.946 1.00 53.69  ? 438 GLN D NE2   1 
ATOM   4407  N N     . TYR B 2 457 ? 101.393 161.521 200.639 1.00 44.18  ? 439 TYR D N     1 
ATOM   4408  C CA    . TYR B 2 457 ? 101.495 162.976 200.701 1.00 44.18  ? 439 TYR D CA    1 
ATOM   4409  C C     . TYR B 2 457 ? 101.458 163.586 199.304 1.00 44.18  ? 439 TYR D C     1 
ATOM   4410  O O     . TYR B 2 457 ? 100.700 164.533 199.043 1.00 44.18  ? 439 TYR D O     1 
ATOM   4411  C CB    . TYR B 2 457 ? 102.782 163.344 201.443 1.00 44.18  ? 439 TYR D CB    1 
ATOM   4412  C CG    . TYR B 2 457 ? 103.219 164.787 201.359 1.00 44.18  ? 439 TYR D CG    1 
ATOM   4413  C CD1   . TYR B 2 457 ? 102.538 165.781 202.041 1.00 44.18  ? 439 TYR D CD1   1 
ATOM   4414  C CD2   . TYR B 2 457 ? 104.339 165.148 200.626 1.00 44.18  ? 439 TYR D CD2   1 
ATOM   4415  C CE1   . TYR B 2 457 ? 102.950 167.096 201.982 1.00 44.18  ? 439 TYR D CE1   1 
ATOM   4416  C CE2   . TYR B 2 457 ? 104.754 166.460 200.559 1.00 44.18  ? 439 TYR D CE2   1 
ATOM   4417  C CZ    . TYR B 2 457 ? 104.056 167.429 201.237 1.00 44.18  ? 439 TYR D CZ    1 
ATOM   4418  O OH    . TYR B 2 457 ? 104.465 168.739 201.173 1.00 44.18  ? 439 TYR D OH    1 
ATOM   4419  N N     . LEU B 2 458 ? 102.220 163.011 198.369 1.00 43.29  ? 440 LEU D N     1 
ATOM   4420  C CA    . LEU B 2 458 ? 102.215 163.555 197.014 1.00 43.29  ? 440 LEU D CA    1 
ATOM   4421  C C     . LEU B 2 458 ? 100.941 163.198 196.253 1.00 43.29  ? 440 LEU D C     1 
ATOM   4422  O O     . LEU B 2 458 ? 100.511 163.975 195.393 1.00 43.29  ? 440 LEU D O     1 
ATOM   4423  C CB    . LEU B 2 458 ? 103.455 163.097 196.247 1.00 43.29  ? 440 LEU D CB    1 
ATOM   4424  C CG    . LEU B 2 458 ? 104.732 163.875 196.592 1.00 43.29  ? 440 LEU D CG    1 
ATOM   4425  C CD1   . LEU B 2 458 ? 105.950 163.107 196.119 1.00 43.29  ? 440 LEU D CD1   1 
ATOM   4426  C CD2   . LEU B 2 458 ? 104.722 165.297 196.012 1.00 43.29  ? 440 LEU D CD2   1 
ATOM   4427  N N     . VAL B 2 459 ? 100.302 162.062 196.560 1.00 51.07  ? 441 VAL D N     1 
ATOM   4428  C CA    . VAL B 2 459 ? 99.003  161.764 195.957 1.00 51.07  ? 441 VAL D CA    1 
ATOM   4429  C C     . VAL B 2 459 ? 97.969  162.782 196.416 1.00 51.07  ? 441 VAL D C     1 
ATOM   4430  O O     . VAL B 2 459 ? 97.130  163.233 195.628 1.00 51.07  ? 441 VAL D O     1 
ATOM   4431  C CB    . VAL B 2 459 ? 98.566  160.321 196.290 1.00 51.07  ? 441 VAL D CB    1 
ATOM   4432  C CG1   . VAL B 2 459 ? 97.079  160.089 195.985 1.00 51.07  ? 441 VAL D CG1   1 
ATOM   4433  C CG2   . VAL B 2 459 ? 99.384  159.313 195.506 1.00 51.07  ? 441 VAL D CG2   1 
ATOM   4434  N N     . GLU B 2 460 ? 98.002  163.146 197.697 1.00 57.24  ? 442 GLU D N     1 
ATOM   4435  C CA    . GLU B 2 460 ? 97.059  164.133 198.207 1.00 57.24  ? 442 GLU D CA    1 
ATOM   4436  C C     . GLU B 2 460 ? 97.312  165.504 197.593 1.00 57.24  ? 442 GLU D C     1 
ATOM   4437  O O     . GLU B 2 460 ? 96.358  166.229 197.270 1.00 57.24  ? 442 GLU D O     1 
ATOM   4438  C CB    . GLU B 2 460 ? 97.146  164.188 199.728 1.00 57.24  ? 442 GLU D CB    1 
ATOM   4439  C CG    . GLU B 2 460 ? 96.580  162.938 200.403 1.00 57.24  ? 442 GLU D CG    1 
ATOM   4440  C CD    . GLU B 2 460 ? 96.913  162.844 201.884 1.00 57.24  ? 442 GLU D CD    1 
ATOM   4441  O OE1   . GLU B 2 460 ? 97.911  163.449 202.329 1.00 57.24  ? 442 GLU D OE1   1 
ATOM   4442  O OE2   . GLU B 2 460 ? 96.168  162.155 202.610 1.00 57.24  ? 442 GLU D OE2   1 
ATOM   4443  N N     . TYR B 2 461 ? 98.588  165.870 197.409 1.00 51.45  ? 443 TYR D N     1 
ATOM   4444  C CA    . TYR B 2 461 ? 98.886  167.114 196.701 1.00 51.45  ? 443 TYR D CA    1 
ATOM   4445  C C     . TYR B 2 461 ? 98.353  167.075 195.275 1.00 51.45  ? 443 TYR D C     1 
ATOM   4446  O O     . TYR B 2 461 ? 97.786  168.059 194.793 1.00 51.45  ? 443 TYR D O     1 
ATOM   4447  C CB    . TYR B 2 461 ? 100.399 167.440 196.747 1.00 51.45  ? 443 TYR D CB    1 
ATOM   4448  C CG    . TYR B 2 461 ? 100.976 168.249 195.570 1.00 51.45  ? 443 TYR D CG    1 
ATOM   4449  C CD1   . TYR B 2 461 ? 101.394 167.647 194.367 1.00 51.45  ? 443 TYR D CD1   1 
ATOM   4450  C CD2   . TYR B 2 461 ? 100.962 169.635 195.613 1.00 51.45  ? 443 TYR D CD2   1 
ATOM   4451  C CE1   . TYR B 2 461 ? 101.856 168.400 193.315 1.00 51.45  ? 443 TYR D CE1   1 
ATOM   4452  C CE2   . TYR B 2 461 ? 101.411 170.390 194.551 1.00 51.45  ? 443 TYR D CE2   1 
ATOM   4453  C CZ    . TYR B 2 461 ? 101.860 169.769 193.411 1.00 51.45  ? 443 TYR D CZ    1 
ATOM   4454  O OH    . TYR B 2 461 ? 102.312 170.526 192.357 1.00 51.45  ? 443 TYR D OH    1 
ATOM   4455  N N     . GLN B 2 462 ? 98.563  165.963 194.570 1.00 53.32  ? 444 GLN D N     1 
ATOM   4456  C CA    . GLN B 2 462 ? 98.133  165.904 193.177 1.00 53.32  ? 444 GLN D CA    1 
ATOM   4457  C C     . GLN B 2 462 ? 96.615  165.904 193.071 1.00 53.32  ? 444 GLN D C     1 
ATOM   4458  O O     . GLN B 2 462 ? 96.064  166.416 192.091 1.00 53.32  ? 444 GLN D O     1 
ATOM   4459  C CB    . GLN B 2 462 ? 98.722  164.674 192.483 1.00 53.32  ? 444 GLN D CB    1 
ATOM   4460  C CG    . GLN B 2 462 ? 99.230  164.945 191.075 1.00 53.32  ? 444 GLN D CG    1 
ATOM   4461  C CD    . GLN B 2 462 ? 100.527 165.736 191.063 1.00 53.32  ? 444 GLN D CD    1 
ATOM   4462  O OE1   . GLN B 2 462 ? 101.501 165.357 191.711 1.00 53.32  ? 444 GLN D OE1   1 
ATOM   4463  N NE2   . GLN B 2 462 ? 100.546 166.838 190.323 1.00 53.32  ? 444 GLN D NE2   1 
ATOM   4464  N N     . SER B 2 463 ? 95.927  165.341 194.067 1.00 58.54  ? 445 SER D N     1 
ATOM   4465  C CA    . SER B 2 463 ? 94.475  165.455 194.119 1.00 58.54  ? 445 SER D CA    1 
ATOM   4466  C C     . SER B 2 463 ? 94.045  166.904 194.309 1.00 58.54  ? 445 SER D C     1 
ATOM   4467  O O     . SER B 2 463 ? 93.090  167.363 193.671 1.00 58.54  ? 445 SER D O     1 
ATOM   4468  C CB    . SER B 2 463 ? 93.923  164.581 195.244 1.00 58.54  ? 445 SER D CB    1 
ATOM   4469  O OG    . SER B 2 463 ? 92.509  164.650 195.295 1.00 58.54  ? 445 SER D OG    1 
ATOM   4470  N N     . GLN B 2 464 ? 94.733  167.638 195.190 1.00 61.82  ? 446 GLN D N     1 
ATOM   4471  C CA    . GLN B 2 464 ? 94.409  169.052 195.376 1.00 61.82  ? 446 GLN D CA    1 
ATOM   4472  C C     . GLN B 2 464 ? 94.710  169.860 194.115 1.00 61.82  ? 446 GLN D C     1 
ATOM   4473  O O     . GLN B 2 464 ? 93.984  170.807 193.791 1.00 61.82  ? 446 GLN D O     1 
ATOM   4474  C CB    . GLN B 2 464 ? 95.187  169.610 196.575 1.00 61.82  ? 446 GLN D CB    1 
ATOM   4475  C CG    . GLN B 2 464 ? 94.878  171.073 196.983 1.00 61.82  ? 446 GLN D CG    1 
ATOM   4476  C CD    . GLN B 2 464 ? 95.992  171.697 197.801 1.00 61.82  ? 446 GLN D CD    1 
ATOM   4477  O OE1   . GLN B 2 464 ? 95.843  171.933 198.999 1.00 61.82  ? 446 GLN D OE1   1 
ATOM   4478  N NE2   . GLN B 2 464 ? 97.119  171.971 197.154 1.00 61.82  ? 446 GLN D NE2   1 
ATOM   4479  N N     . TYR B 2 465 ? 95.777  169.506 193.399 1.00 60.10  ? 447 TYR D N     1 
ATOM   4480  C CA    . TYR B 2 465 ? 96.337  170.401 192.391 1.00 60.10  ? 447 TYR D CA    1 
ATOM   4481  C C     . TYR B 2 465 ? 95.445  170.498 191.160 1.00 60.10  ? 447 TYR D C     1 
ATOM   4482  O O     . TYR B 2 465 ? 95.240  171.592 190.623 1.00 60.10  ? 447 TYR D O     1 
ATOM   4483  C CB    . TYR B 2 465 ? 97.738  169.915 192.011 1.00 60.10  ? 447 TYR D CB    1 
ATOM   4484  C CG    . TYR B 2 465 ? 98.505  170.800 191.051 1.00 60.10  ? 447 TYR D CG    1 
ATOM   4485  C CD1   . TYR B 2 465 ? 98.668  172.160 191.292 1.00 60.10  ? 447 TYR D CD1   1 
ATOM   4486  C CD2   . TYR B 2 465 ? 99.083  170.267 189.908 1.00 60.10  ? 447 TYR D CD2   1 
ATOM   4487  C CE1   . TYR B 2 465 ? 99.373  172.960 190.418 1.00 60.10  ? 447 TYR D CE1   1 
ATOM   4488  C CE2   . TYR B 2 465 ? 99.791  171.059 189.030 1.00 60.10  ? 447 TYR D CE2   1 
ATOM   4489  C CZ    . TYR B 2 465 ? 99.933  172.403 189.289 1.00 60.10  ? 447 TYR D CZ    1 
ATOM   4490  O OH    . TYR B 2 465 ? 100.637 173.190 188.412 1.00 60.10  ? 447 TYR D OH    1 
ATOM   4491  N N     . MET B 2 466 ? 94.913  169.374 190.693 1.00 69.07  ? 448 MET D N     1 
ATOM   4492  C CA    . MET B 2 466 ? 94.053  169.388 189.511 1.00 69.07  ? 448 MET D CA    1 
ATOM   4493  C C     . MET B 2 466 ? 92.720  170.057 189.827 1.00 69.07  ? 448 MET D C     1 
ATOM   4494  O O     . MET B 2 466 ? 92.000  170.493 188.930 1.00 69.07  ? 448 MET D O     1 
ATOM   4495  C CB    . MET B 2 466 ? 93.836  167.963 188.952 1.00 69.07  ? 448 MET D CB    1 
ATOM   4496  C CG    . MET B 2 466 ? 93.371  166.840 189.918 1.00 69.07  ? 448 MET D CG    1 
ATOM   4497  S SD    . MET B 2 466 ? 91.730  166.965 190.667 1.00 69.07  ? 448 MET D SD    1 
ATOM   4498  C CE    . MET B 2 466 ? 90.685  166.749 189.229 1.00 69.07  ? 448 MET D CE    1 
ATOM   4499  N N     . ILE C 1 47  ? 92.654  160.101 133.719 1.00 32.61  ? 18  ILE C N     1 
ATOM   4500  C CA    . ILE C 1 47  ? 91.409  160.869 133.441 1.00 32.61  ? 18  ILE C CA    1 
ATOM   4501  C C     . ILE C 1 47  ? 90.642  160.216 132.291 1.00 32.61  ? 18  ILE C C     1 
ATOM   4502  O O     . ILE C 1 47  ? 90.120  160.892 131.405 1.00 32.61  ? 18  ILE C O     1 
ATOM   4503  C CB    . ILE C 1 47  ? 91.729  162.358 133.151 1.00 32.61  ? 18  ILE C CB    1 
ATOM   4504  C CG1   . ILE C 1 47  ? 92.849  162.496 132.109 1.00 32.61  ? 18  ILE C CG1   1 
ATOM   4505  C CG2   . ILE C 1 47  ? 92.118  163.073 134.434 1.00 32.61  ? 18  ILE C CG2   1 
ATOM   4506  C CD1   . ILE C 1 47  ? 92.906  163.859 131.452 1.00 32.61  ? 18  ILE C CD1   1 
ATOM   4507  N N     . ALA C 1 48  ? 90.586  158.883 132.307 1.00 32.25  ? 19  ALA C N     1 
ATOM   4508  C CA    . ALA C 1 48  ? 89.821  158.171 131.290 1.00 32.25  ? 19  ALA C CA    1 
ATOM   4509  C C     . ALA C 1 48  ? 88.325  158.401 131.448 1.00 32.25  ? 19  ALA C C     1 
ATOM   4510  O O     . ALA C 1 48  ? 87.599  158.433 130.448 1.00 32.25  ? 19  ALA C O     1 
ATOM   4511  C CB    . ALA C 1 48  ? 90.132  156.676 131.350 1.00 32.25  ? 19  ALA C CB    1 
ATOM   4512  N N     . THR C 1 49  ? 87.858  158.702 132.670 1.00 34.68  ? 20  THR C N     1 
ATOM   4513  C CA    . THR C 1 49  ? 86.410  158.822 132.995 1.00 34.68  ? 20  THR C CA    1 
ATOM   4514  C C     . THR C 1 49  ? 85.851  160.217 132.774 1.00 34.68  ? 20  THR C C     1 
ATOM   4515  O O     . THR C 1 49  ? 84.613  160.326 132.700 1.00 34.68  ? 20  THR C O     1 
ATOM   4516  C CB    . THR C 1 49  ? 86.212  158.385 134.445 1.00 34.68  ? 20  THR C CB    1 
ATOM   4517  O OG1   . THR C 1 49  ? 84.814  158.177 134.616 1.00 34.68  ? 20  THR C OG1   1 
ATOM   4518  C CG2   . THR C 1 49  ? 86.672  159.422 135.450 1.00 34.68  ? 20  THR C CG2   1 
ATOM   4519  N N     . HIS C 1 50  ? 86.685  161.253 132.700 1.00 32.47  ? 21  HIS C N     1 
ATOM   4520  C CA    . HIS C 1 50  ? 86.242  162.653 132.483 1.00 32.47  ? 21  HIS C CA    1 
ATOM   4521  C C     . HIS C 1 50  ? 86.734  163.150 131.116 1.00 32.47  ? 21  HIS C C     1 
ATOM   4522  O O     . HIS C 1 50  ? 87.116  164.328 131.049 1.00 32.47  ? 21  HIS C O     1 
ATOM   4523  C CB    . HIS C 1 50  ? 86.794  163.577 133.573 1.00 32.47  ? 21  HIS C CB    1 
ATOM   4524  C CG    . HIS C 1 50  ? 86.755  163.082 134.972 1.00 32.47  ? 21  HIS C CG    1 
ATOM   4525  N ND1   . HIS C 1 50  ? 87.777  162.350 135.530 1.00 32.47  ? 21  HIS C ND1   1 
ATOM   4526  C CD2   . HIS C 1 50  ? 85.863  163.266 135.940 1.00 32.47  ? 21  HIS C CD2   1 
ATOM   4527  C CE1   . HIS C 1 50  ? 87.480  162.079 136.791 1.00 32.47  ? 21  HIS C CE1   1 
ATOM   4528  N NE2   . HIS C 1 50  ? 86.320  162.625 137.060 1.00 32.47  ? 21  HIS C NE2   1 
ATOM   4529  N N     . THR C 1 51  ? 86.770  162.322 130.062 1.00 35.80  ? 22  THR C N     1 
ATOM   4530  C CA    . THR C 1 51  ? 87.166  162.791 128.739 1.00 35.80  ? 22  THR C CA    1 
ATOM   4531  C C     . THR C 1 51  ? 86.175  163.781 128.134 1.00 35.80  ? 22  THR C C     1 
ATOM   4532  O O     . THR C 1 51  ? 86.538  164.488 127.188 1.00 35.80  ? 22  THR C O     1 
ATOM   4533  C CB    . THR C 1 51  ? 87.354  161.602 127.793 1.00 35.80  ? 22  THR C CB    1 
ATOM   4534  O OG1   . THR C 1 51  ? 87.998  162.045 126.592 1.00 35.80  ? 22  THR C OG1   1 
ATOM   4535  C CG2   . THR C 1 51  ? 86.020  160.959 127.436 1.00 35.80  ? 22  THR C CG2   1 
ATOM   4536  N N     . HIS C 1 52  ? 84.959  163.858 128.682 1.00 35.77  ? 23  HIS C N     1 
ATOM   4537  C CA    . HIS C 1 52  ? 83.903  164.777 128.176 1.00 35.77  ? 23  HIS C CA    1 
ATOM   4538  C C     . HIS C 1 52  ? 84.067  166.175 128.784 1.00 35.77  ? 23  HIS C C     1 
ATOM   4539  O O     . HIS C 1 52  ? 83.393  167.087 128.260 1.00 35.77  ? 23  HIS C O     1 
ATOM   4540  C CB    . HIS C 1 52  ? 82.510  164.206 128.467 1.00 35.77  ? 23  HIS C CB    1 
ATOM   4541  C CG    . HIS C 1 52  ? 82.230  164.051 129.921 1.00 35.77  ? 23  HIS C CG    1 
ATOM   4542  N ND1   . HIS C 1 52  ? 82.470  162.857 130.561 1.00 35.77  ? 23  HIS C ND1   1 
ATOM   4543  C CD2   . HIS C 1 52  ? 81.772  164.888 130.856 1.00 35.77  ? 23  HIS C CD2   1 
ATOM   4544  C CE1   . HIS C 1 52  ? 82.163  162.978 131.839 1.00 35.77  ? 23  HIS C CE1   1 
ATOM   4545  N NE2   . HIS C 1 52  ? 81.736  164.201 132.042 1.00 35.77  ? 23  HIS C NE2   1 
ATOM   4546  N N     . ILE C 1 53  ? 84.898  166.361 129.822 1.00 34.27  ? 24  ILE C N     1 
ATOM   4547  C CA    . ILE C 1 53  ? 85.052  167.652 130.492 1.00 34.27  ? 24  ILE C CA    1 
ATOM   4548  C C     . ILE C 1 53  ? 85.991  168.498 129.637 1.00 34.27  ? 24  ILE C C     1 
ATOM   4549  O O     . ILE C 1 53  ? 87.212  168.385 129.745 1.00 34.27  ? 24  ILE C O     1 
ATOM   4550  C CB    . ILE C 1 53  ? 85.584  167.501 131.920 1.00 34.27  ? 24  ILE C CB    1 
ATOM   4551  C CG1   . ILE C 1 53  ? 84.693  166.580 132.776 1.00 34.27  ? 24  ILE C CG1   1 
ATOM   4552  C CG2   . ILE C 1 53  ? 85.772  168.877 132.561 1.00 34.27  ? 24  ILE C CG2   1 
ATOM   4553  C CD1   . ILE C 1 53  ? 83.256  167.037 132.966 1.00 34.27  ? 24  ILE C CD1   1 
ATOM   4554  N N     . LYS C 1 54  ? 85.421  169.352 128.787 1.00 34.79  ? 25  LYS C N     1 
ATOM   4555  C CA    . LYS C 1 54  ? 86.206  170.266 127.964 1.00 34.79  ? 25  LYS C CA    1 
ATOM   4556  C C     . LYS C 1 54  ? 86.583  171.542 128.702 1.00 34.79  ? 25  LYS C C     1 
ATOM   4557  O O     . LYS C 1 54  ? 87.627  172.134 128.407 1.00 34.79  ? 25  LYS C O     1 
ATOM   4558  C CB    . LYS C 1 54  ? 85.434  170.632 126.691 1.00 34.79  ? 25  LYS C CB    1 
ATOM   4559  C CG    . LYS C 1 54  ? 84.794  169.459 125.942 1.00 34.79  ? 25  LYS C CG    1 
ATOM   4560  C CD    . LYS C 1 54  ? 85.801  168.373 125.584 1.00 34.79  ? 25  LYS C CD    1 
ATOM   4561  C CE    . LYS C 1 54  ? 85.182  167.326 124.675 1.00 34.79  ? 25  LYS C CE    1 
ATOM   4562  N NZ    . LYS C 1 54  ? 86.118  166.201 124.405 1.00 34.79  ? 25  LYS C NZ    1 
ATOM   4563  N N     . GLY C 1 55  ? 85.763  171.978 129.647 1.00 34.87  ? 26  GLY C N     1 
ATOM   4564  C CA    . GLY C 1 55  ? 86.038  173.191 130.386 1.00 34.87  ? 26  GLY C CA    1 
ATOM   4565  C C     . GLY C 1 55  ? 84.876  173.505 131.299 1.00 34.87  ? 26  GLY C C     1 
ATOM   4566  O O     . GLY C 1 55  ? 83.863  172.803 131.315 1.00 34.87  ? 26  GLY C O     1 
ATOM   4567  N N     . LEU C 1 56  ? 85.038  174.589 132.061 1.00 36.43  ? 27  LEU C N     1 
ATOM   4568  C CA    . LEU C 1 56  ? 84.009  174.971 133.024 1.00 36.43  ? 27  LEU C CA    1 
ATOM   4569  C C     . LEU C 1 56  ? 82.707  175.375 132.341 1.00 36.43  ? 27  LEU C C     1 
ATOM   4570  O O     . LEU C 1 56  ? 81.633  175.254 132.942 1.00 36.43  ? 27  LEU C O     1 
ATOM   4571  C CB    . LEU C 1 56  ? 84.511  176.117 133.905 1.00 36.43  ? 27  LEU C CB    1 
ATOM   4572  C CG    . LEU C 1 56  ? 85.689  175.856 134.848 1.00 36.43  ? 27  LEU C CG    1 
ATOM   4573  C CD1   . LEU C 1 56  ? 86.053  177.139 135.572 1.00 36.43  ? 27  LEU C CD1   1 
ATOM   4574  C CD2   . LEU C 1 56  ? 85.390  174.752 135.854 1.00 36.43  ? 27  LEU C CD2   1 
ATOM   4575  N N     . GLY C 1 57  ? 82.771  175.852 131.101 1.00 39.59  ? 28  GLY C N     1 
ATOM   4576  C CA    . GLY C 1 57  ? 81.569  176.254 130.400 1.00 39.59  ? 28  GLY C CA    1 
ATOM   4577  C C     . GLY C 1 57  ? 80.970  177.511 130.991 1.00 39.59  ? 28  GLY C C     1 
ATOM   4578  O O     . GLY C 1 57  ? 79.881  177.474 131.572 1.00 39.59  ? 28  GLY C O     1 
ATOM   4579  N N     . LEU C 1 58  ? 81.686  178.626 130.843 1.00 41.86  ? 29  LEU C N     1 
ATOM   4580  C CA    . LEU C 1 58  ? 81.328  179.911 131.424 1.00 41.86  ? 29  LEU C CA    1 
ATOM   4581  C C     . LEU C 1 58  ? 81.022  180.914 130.322 1.00 41.86  ? 29  LEU C C     1 
ATOM   4582  O O     . LEU C 1 58  ? 81.634  180.891 129.250 1.00 41.86  ? 29  LEU C O     1 
ATOM   4583  C CB    . LEU C 1 58  ? 82.461  180.450 132.302 1.00 41.86  ? 29  LEU C CB    1 
ATOM   4584  C CG    . LEU C 1 58  ? 82.952  179.535 133.425 1.00 41.86  ? 29  LEU C CG    1 
ATOM   4585  C CD1   . LEU C 1 58  ? 84.170  180.135 134.095 1.00 41.86  ? 29  LEU C CD1   1 
ATOM   4586  C CD2   . LEU C 1 58  ? 81.854  179.287 134.446 1.00 41.86  ? 29  LEU C CD2   1 
ATOM   4587  N N     . GLU C 1 59  ? 80.068  181.800 130.599 1.00 46.29  ? 30  GLU C N     1 
ATOM   4588  C CA    . GLU C 1 59  ? 79.737  182.874 129.682 1.00 46.29  ? 30  GLU C CA    1 
ATOM   4589  C C     . GLU C 1 59  ? 80.845  183.928 129.711 1.00 46.29  ? 30  GLU C C     1 
ATOM   4590  O O     . GLU C 1 59  ? 81.779  183.833 130.511 1.00 46.29  ? 30  GLU C O     1 
ATOM   4591  C CB    . GLU C 1 59  ? 78.386  183.488 130.054 1.00 46.29  ? 30  GLU C CB    1 
ATOM   4592  C CG    . GLU C 1 59  ? 77.195  182.681 129.579 1.00 46.29  ? 30  GLU C CG    1 
ATOM   4593  C CD    . GLU C 1 59  ? 75.951  182.928 130.408 1.00 46.29  ? 30  GLU C CD    1 
ATOM   4594  O OE1   . GLU C 1 59  ? 75.708  184.093 130.786 1.00 46.29  ? 30  GLU C OE1   1 
ATOM   4595  O OE2   . GLU C 1 59  ? 75.215  181.957 130.681 1.00 46.29  ? 30  GLU C OE2   1 
ATOM   4596  N N     . PRO C 1 60  ? 80.788  184.936 128.829 1.00 48.42  ? 31  PRO C N     1 
ATOM   4597  C CA    . PRO C 1 60  ? 81.702  186.082 128.987 1.00 48.42  ? 31  PRO C CA    1 
ATOM   4598  C C     . PRO C 1 60  ? 81.552  186.803 130.318 1.00 48.42  ? 31  PRO C C     1 
ATOM   4599  O O     . PRO C 1 60  ? 82.533  187.365 130.819 1.00 48.42  ? 31  PRO C O     1 
ATOM   4600  C CB    . PRO C 1 60  ? 81.335  187.007 127.817 1.00 48.42  ? 31  PRO C CB    1 
ATOM   4601  C CG    . PRO C 1 60  ? 80.400  186.255 126.941 1.00 48.42  ? 31  PRO C CG    1 
ATOM   4602  C CD    . PRO C 1 60  ? 80.193  184.886 127.482 1.00 48.42  ? 31  PRO C CD    1 
ATOM   4603  N N     . THR C 1 61  ? 80.355  186.799 130.906 1.00 47.37  ? 32  THR C N     1 
ATOM   4604  C CA    . THR C 1 61  ? 80.113  187.459 132.184 1.00 47.37  ? 32  THR C CA    1 
ATOM   4605  C C     . THR C 1 61  ? 80.558  186.632 133.388 1.00 47.37  ? 32  THR C C     1 
ATOM   4606  O O     . THR C 1 61  ? 80.441  187.120 134.517 1.00 47.37  ? 32  THR C O     1 
ATOM   4607  C CB    . THR C 1 61  ? 78.625  187.800 132.337 1.00 47.37  ? 32  THR C CB    1 
ATOM   4608  O OG1   . THR C 1 61  ? 77.885  186.609 132.636 1.00 47.37  ? 32  THR C OG1   1 
ATOM   4609  C CG2   . THR C 1 61  ? 78.070  188.449 131.070 1.00 47.37  ? 32  THR C CG2   1 
ATOM   4610  N N     . GLY C 1 62  ? 81.045  185.402 133.189 1.00 47.26  ? 33  GLY C N     1 
ATOM   4611  C CA    . GLY C 1 62  ? 81.529  184.571 134.269 1.00 47.26  ? 33  GLY C CA    1 
ATOM   4612  C C     . GLY C 1 62  ? 80.501  183.648 134.889 1.00 47.26  ? 33  GLY C C     1 
ATOM   4613  O O     . GLY C 1 62  ? 80.885  182.743 135.639 1.00 47.26  ? 33  GLY C O     1 
ATOM   4614  N N     . ILE C 1 63  ? 79.215  183.836 134.604 1.00 44.23  ? 34  ILE C N     1 
ATOM   4615  C CA    . ILE C 1 63  ? 78.172  182.969 135.147 1.00 44.23  ? 34  ILE C CA    1 
ATOM   4616  C C     . ILE C 1 63  ? 78.218  181.657 134.366 1.00 44.23  ? 34  ILE C C     1 
ATOM   4617  O O     . ILE C 1 63  ? 78.408  181.702 133.142 1.00 44.23  ? 34  ILE C O     1 
ATOM   4618  C CB    . ILE C 1 63  ? 76.778  183.617 135.055 1.00 44.23  ? 34  ILE C CB    1 
ATOM   4619  C CG1   . ILE C 1 63  ? 76.756  185.046 135.642 1.00 44.23  ? 34  ILE C CG1   1 
ATOM   4620  C CG2   . ILE C 1 63  ? 75.731  182.720 135.730 1.00 44.23  ? 34  ILE C CG2   1 
ATOM   4621  C CD1   . ILE C 1 63  ? 77.171  185.174 137.109 1.00 44.23  ? 34  ILE C CD1   1 
ATOM   4622  N N     . PRO C 1 64  ? 78.058  180.478 134.977 1.00 41.31  ? 35  PRO C N     1 
ATOM   4623  C CA    . PRO C 1 64  ? 78.057  179.252 134.173 1.00 41.31  ? 35  PRO C CA    1 
ATOM   4624  C C     . PRO C 1 64  ? 76.793  179.116 133.339 1.00 41.31  ? 35  PRO C C     1 
ATOM   4625  O O     . PRO C 1 64  ? 75.733  179.657 133.663 1.00 41.31  ? 35  PRO C O     1 
ATOM   4626  C CB    . PRO C 1 64  ? 78.142  178.129 135.213 1.00 41.31  ? 35  PRO C CB    1 
ATOM   4627  C CG    . PRO C 1 64  ? 78.519  178.775 136.468 1.00 41.31  ? 35  PRO C CG    1 
ATOM   4628  C CD    . PRO C 1 64  ? 77.945  180.140 136.408 1.00 41.31  ? 35  PRO C CD    1 
ATOM   4629  N N     . ILE C 1 65  ? 76.929  178.369 132.244 1.00 41.50  ? 36  ILE C N     1 
ATOM   4630  C CA    . ILE C 1 65  ? 75.789  177.925 131.449 1.00 41.50  ? 36  ILE C CA    1 
ATOM   4631  C C     . ILE C 1 65  ? 75.250  176.657 132.099 1.00 41.50  ? 36  ILE C C     1 
ATOM   4632  O O     . ILE C 1 65  ? 76.000  175.896 132.720 1.00 41.50  ? 36  ILE C O     1 
ATOM   4633  C CB    . ILE C 1 65  ? 76.182  177.687 129.970 1.00 41.50  ? 36  ILE C CB    1 
ATOM   4634  C CG1   . ILE C 1 65  ? 76.782  178.943 129.304 1.00 41.50  ? 36  ILE C CG1   1 
ATOM   4635  C CG2   . ILE C 1 65  ? 74.967  177.222 129.153 1.00 41.50  ? 36  ILE C CG2   1 
ATOM   4636  C CD1   . ILE C 1 65  ? 77.619  178.656 128.062 1.00 41.50  ? 36  ILE C CD1   1 
ATOM   4637  N N     . LYS C 1 66  ? 73.936  176.438 131.987 1.00 38.75  ? 37  LYS C N     1 
ATOM   4638  C CA    . LYS C 1 66  ? 73.322  175.275 132.623 1.00 38.75  ? 37  LYS C CA    1 
ATOM   4639  C C     . LYS C 1 66  ? 73.846  173.972 132.029 1.00 38.75  ? 37  LYS C C     1 
ATOM   4640  O O     . LYS C 1 66  ? 74.090  173.011 132.765 1.00 38.75  ? 37  LYS C O     1 
ATOM   4641  C CB    . LYS C 1 66  ? 71.798  175.350 132.493 1.00 38.75  ? 37  LYS C CB    1 
ATOM   4642  C CG    . LYS C 1 66  ? 71.017  174.374 133.385 1.00 38.75  ? 37  LYS C CG    1 
ATOM   4643  C CD    . LYS C 1 66  ? 71.135  174.705 134.872 1.00 38.75  ? 37  LYS C CD    1 
ATOM   4644  C CE    . LYS C 1 66  ? 69.987  174.115 135.679 1.00 38.75  ? 37  LYS C CE    1 
ATOM   4645  N NZ    . LYS C 1 66  ? 70.019  172.626 135.684 1.00 38.75  ? 37  LYS C NZ    1 
ATOM   4646  N N     . LEU C 1 67  ? 74.009  173.918 130.706 1.00 38.78  ? 38  LEU C N     1 
ATOM   4647  C CA    . LEU C 1 67  ? 74.591  172.767 130.012 1.00 38.78  ? 38  LEU C CA    1 
ATOM   4648  C C     . LEU C 1 67  ? 75.580  173.288 128.979 1.00 38.78  ? 38  LEU C C     1 
ATOM   4649  O O     . LEU C 1 67  ? 75.167  173.800 127.934 1.00 38.78  ? 38  LEU C O     1 
ATOM   4650  C CB    . LEU C 1 67  ? 73.521  171.912 129.330 1.00 38.78  ? 38  LEU C CB    1 
ATOM   4651  C CG    . LEU C 1 67  ? 72.688  170.919 130.153 1.00 38.78  ? 38  LEU C CG    1 
ATOM   4652  C CD1   . LEU C 1 67  ? 71.730  171.612 131.119 1.00 38.78  ? 38  LEU C CD1   1 
ATOM   4653  C CD2   . LEU C 1 67  ? 71.924  169.968 129.231 1.00 38.78  ? 38  LEU C CD2   1 
ATOM   4654  N N     . ALA C 1 68  ? 76.874  173.155 129.256 1.00 37.42  ? 39  ALA C N     1 
ATOM   4655  C CA    . ALA C 1 68  ? 77.893  173.555 128.294 1.00 37.42  ? 39  ALA C CA    1 
ATOM   4656  C C     . ALA C 1 68  ? 79.235  172.983 128.718 1.00 37.42  ? 39  ALA C C     1 
ATOM   4657  O O     . ALA C 1 68  ? 79.501  172.813 129.911 1.00 37.42  ? 39  ALA C O     1 
ATOM   4658  C CB    . ALA C 1 68  ? 77.997  175.079 128.173 1.00 37.42  ? 39  ALA C CB    1 
ATOM   4659  N N     . ALA C 1 69  ? 80.074  172.695 127.721 1.00 35.08  ? 40  ALA C N     1 
ATOM   4660  C CA    . ALA C 1 69  ? 81.446  172.227 127.931 1.00 35.08  ? 40  ALA C CA    1 
ATOM   4661  C C     . ALA C 1 69  ? 81.498  170.920 128.718 1.00 35.08  ? 40  ALA C C     1 
ATOM   4662  O O     . ALA C 1 69  ? 82.455  170.668 129.454 1.00 35.08  ? 40  ALA C O     1 
ATOM   4663  C CB    . ALA C 1 69  ? 82.288  173.298 128.628 1.00 35.08  ? 40  ALA C CB    1 
ATOM   4664  N N     . GLY C 1 70  ? 80.471  170.080 128.578 1.00 33.43  ? 41  GLY C N     1 
ATOM   4665  C CA    . GLY C 1 70  ? 80.390  168.825 129.294 1.00 33.43  ? 41  GLY C CA    1 
ATOM   4666  C C     . GLY C 1 70  ? 79.811  168.910 130.689 1.00 33.43  ? 41  GLY C C     1 
ATOM   4667  O O     . GLY C 1 70  ? 79.387  167.881 131.227 1.00 33.43  ? 41  GLY C O     1 
ATOM   4668  N N     . PHE C 1 71  ? 79.792  170.098 131.306 1.00 32.93  ? 42  PHE C N     1 
ATOM   4669  C CA    . PHE C 1 71  ? 79.333  170.251 132.715 1.00 32.93  ? 42  PHE C CA    1 
ATOM   4670  C C     . PHE C 1 71  ? 77.826  170.478 132.745 1.00 32.93  ? 42  PHE C C     1 
ATOM   4671  O O     . PHE C 1 71  ? 77.385  171.486 132.153 1.00 32.93  ? 42  PHE C O     1 
ATOM   4672  C CB    . PHE C 1 71  ? 80.090  171.407 133.375 1.00 32.93  ? 42  PHE C CB    1 
ATOM   4673  C CG    . PHE C 1 71  ? 81.113  170.955 134.406 1.00 32.93  ? 42  PHE C CG    1 
ATOM   4674  C CD1   . PHE C 1 71  ? 80.724  170.676 135.709 1.00 32.93  ? 42  PHE C CD1   1 
ATOM   4675  C CD2   . PHE C 1 71  ? 82.452  170.799 134.070 1.00 32.93  ? 42  PHE C CD2   1 
ATOM   4676  C CE1   . PHE C 1 71  ? 81.647  170.263 136.652 1.00 32.93  ? 42  PHE C CE1   1 
ATOM   4677  C CE2   . PHE C 1 71  ? 83.372  170.383 135.019 1.00 32.93  ? 42  PHE C CE2   1 
ATOM   4678  C CZ    . PHE C 1 71  ? 82.966  170.116 136.305 1.00 32.93  ? 42  PHE C CZ    1 
ATOM   4679  N N     . VAL C 1 72  ? 77.067  169.594 133.408 1.00 35.67  ? 43  VAL C N     1 
ATOM   4680  C CA    . VAL C 1 72  ? 75.584  169.755 133.555 1.00 35.67  ? 43  VAL C CA    1 
ATOM   4681  C C     . VAL C 1 72  ? 75.272  169.876 135.059 1.00 35.67  ? 43  VAL C C     1 
ATOM   4682  O O     . VAL C 1 72  ? 75.469  168.877 135.784 1.00 35.67  ? 43  VAL C O     1 
ATOM   4683  C CB    . VAL C 1 72  ? 74.741  168.665 132.858 1.00 35.67  ? 43  VAL C CB    1 
ATOM   4684  C CG1   . VAL C 1 72  ? 75.153  167.244 133.206 1.00 35.67  ? 43  VAL C CG1   1 
ATOM   4685  C CG2   . VAL C 1 72  ? 73.252  168.860 133.096 1.00 35.67  ? 43  VAL C CG2   1 
ATOM   4686  N N     . GLY C 1 73  ? 74.860  171.066 135.512 1.00 33.94  ? 44  GLY C N     1 
ATOM   4687  C CA    . GLY C 1 73  ? 74.531  171.340 136.923 1.00 33.94  ? 44  GLY C CA    1 
ATOM   4688  C C     . GLY C 1 73  ? 75.730  171.874 137.668 1.00 33.94  ? 44  GLY C C     1 
ATOM   4689  O O     . GLY C 1 73  ? 76.720  172.194 136.994 1.00 33.94  ? 44  GLY C O     1 
ATOM   4690  N N     . GLN C 1 74  ? 75.655  172.014 138.993 1.00 32.46  ? 45  GLN C N     1 
ATOM   4691  C CA    . GLN C 1 74  ? 76.805  172.418 139.802 1.00 32.46  ? 45  GLN C CA    1 
ATOM   4692  C C     . GLN C 1 74  ? 77.217  173.858 139.485 1.00 32.46  ? 45  GLN C C     1 
ATOM   4693  O O     . GLN C 1 74  ? 78.372  174.150 139.170 1.00 32.46  ? 45  GLN C O     1 
ATOM   4694  C CB    . GLN C 1 74  ? 77.968  171.440 139.598 1.00 32.46  ? 45  GLN C CB    1 
ATOM   4695  C CG    . GLN C 1 74  ? 78.953  171.374 140.752 1.00 32.46  ? 45  GLN C CG    1 
ATOM   4696  C CD    . GLN C 1 74  ? 78.398  170.655 141.965 1.00 32.46  ? 45  GLN C CD    1 
ATOM   4697  O OE1   . GLN C 1 74  ? 78.210  171.254 143.022 1.00 32.46  ? 45  GLN C OE1   1 
ATOM   4698  N NE2   . GLN C 1 74  ? 78.148  169.361 141.823 1.00 32.46  ? 45  GLN C NE2   1 
ATOM   4699  N N     . LEU C 1 75  ? 76.250  174.772 139.585 1.00 36.90  ? 46  LEU C N     1 
ATOM   4700  C CA    . LEU C 1 75  ? 76.479  176.141 139.134 1.00 36.90  ? 46  LEU C CA    1 
ATOM   4701  C C     . LEU C 1 75  ? 77.364  176.917 140.104 1.00 36.90  ? 46  LEU C C     1 
ATOM   4702  O O     . LEU C 1 75  ? 78.222  177.698 139.673 1.00 36.90  ? 46  LEU C O     1 
ATOM   4703  C CB    . LEU C 1 75  ? 75.144  176.860 138.943 1.00 36.90  ? 46  LEU C CB    1 
ATOM   4704  C CG    . LEU C 1 75  ? 74.274  176.400 137.766 1.00 36.90  ? 46  LEU C CG    1 
ATOM   4705  C CD1   . LEU C 1 75  ? 73.366  175.225 138.134 1.00 36.90  ? 46  LEU C CD1   1 
ATOM   4706  C CD2   . LEU C 1 75  ? 73.453  177.568 137.234 1.00 36.90  ? 46  LEU C CD2   1 
ATOM   4707  N N     . GLU C 1 76  ? 77.160  176.730 141.412 1.00 38.12  ? 47  GLU C N     1 
ATOM   4708  C CA    . GLU C 1 76  ? 77.924  177.479 142.407 1.00 38.12  ? 47  GLU C CA    1 
ATOM   4709  C C     . GLU C 1 76  ? 79.408  177.145 142.329 1.00 38.12  ? 47  GLU C C     1 
ATOM   4710  O O     . GLU C 1 76  ? 80.262  178.041 142.285 1.00 38.12  ? 47  GLU C O     1 
ATOM   4711  C CB    . GLU C 1 76  ? 77.394  177.174 143.809 1.00 38.12  ? 47  GLU C CB    1 
ATOM   4712  C CG    . GLU C 1 76  ? 76.028  177.761 144.121 1.00 38.12  ? 47  GLU C CG    1 
ATOM   4713  C CD    . GLU C 1 76  ? 75.861  178.082 145.594 1.00 38.12  ? 47  GLU C CD    1 
ATOM   4714  O OE1   . GLU C 1 76  ? 76.154  177.204 146.432 1.00 38.12  ? 47  GLU C OE1   1 
ATOM   4715  O OE2   . GLU C 1 76  ? 75.436  179.212 145.915 1.00 38.12  ? 47  GLU C OE2   1 
ATOM   4716  N N     . ALA C 1 77  ? 79.730  175.853 142.291 1.00 33.09  ? 48  ALA C N     1 
ATOM   4717  C CA    . ALA C 1 77  ? 81.126  175.447 142.238 1.00 33.09  ? 48  ALA C CA    1 
ATOM   4718  C C     . ALA C 1 77  ? 81.766  175.820 140.910 1.00 33.09  ? 48  ALA C C     1 
ATOM   4719  O O     . ALA C 1 77  ? 82.951  176.156 140.875 1.00 33.09  ? 48  ALA C O     1 
ATOM   4720  C CB    . ALA C 1 77  ? 81.241  173.947 142.482 1.00 33.09  ? 48  ALA C CB    1 
ATOM   4721  N N     . ARG C 1 78  ? 81.008  175.776 139.812 1.00 35.96  ? 49  ARG C N     1 
ATOM   4722  C CA    . ARG C 1 78  ? 81.558  176.189 138.523 1.00 35.96  ? 49  ARG C CA    1 
ATOM   4723  C C     . ARG C 1 78  ? 81.857  177.683 138.499 1.00 35.96  ? 49  ARG C C     1 
ATOM   4724  O O     . ARG C 1 78  ? 82.886  178.104 137.960 1.00 35.96  ? 49  ARG C O     1 
ATOM   4725  C CB    . ARG C 1 78  ? 80.596  175.819 137.398 1.00 35.96  ? 49  ARG C CB    1 
ATOM   4726  C CG    . ARG C 1 78  ? 80.600  174.339 137.059 1.00 35.96  ? 49  ARG C CG    1 
ATOM   4727  C CD    . ARG C 1 78  ? 79.423  173.958 136.179 1.00 35.96  ? 49  ARG C CD    1 
ATOM   4728  N NE    . ARG C 1 78  ? 79.525  174.559 134.853 1.00 35.96  ? 49  ARG C NE    1 
ATOM   4729  C CZ    . ARG C 1 78  ? 78.522  174.727 133.998 1.00 35.96  ? 49  ARG C CZ    1 
ATOM   4730  N NH1   . ARG C 1 78  ? 77.290  174.314 134.265 1.00 35.96  ? 49  ARG C NH1   1 
ATOM   4731  N NH2   . ARG C 1 78  ? 78.761  175.323 132.834 1.00 35.96  ? 49  ARG C NH2   1 
ATOM   4732  N N     . GLU C 1 79  ? 80.972  178.501 139.075 1.00 38.42  ? 50  GLU C N     1 
ATOM   4733  C CA    . GLU C 1 79  ? 81.241  179.935 139.158 1.00 38.42  ? 50  GLU C CA    1 
ATOM   4734  C C     . GLU C 1 79  ? 82.453  180.215 140.038 1.00 38.42  ? 50  GLU C C     1 
ATOM   4735  O O     . GLU C 1 79  ? 83.287  181.073 139.713 1.00 38.42  ? 50  GLU C O     1 
ATOM   4736  C CB    . GLU C 1 79  ? 80.009  180.663 139.694 1.00 38.42  ? 50  GLU C CB    1 
ATOM   4737  C CG    . GLU C 1 79  ? 80.074  182.177 139.581 1.00 38.42  ? 50  GLU C CG    1 
ATOM   4738  C CD    . GLU C 1 79  ? 78.798  182.847 140.046 1.00 38.42  ? 50  GLU C CD    1 
ATOM   4739  O OE1   . GLU C 1 79  ? 77.868  182.130 140.469 1.00 38.42  ? 50  GLU C OE1   1 
ATOM   4740  O OE2   . GLU C 1 79  ? 78.727  184.092 139.993 1.00 38.42  ? 50  GLU C OE2   1 
ATOM   4741  N N     . ALA C 1 80  ? 82.565  179.498 141.159 1.00 36.20  ? 51  ALA C N     1 
ATOM   4742  C CA    . ALA C 1 80  ? 83.724  179.658 142.030 1.00 36.20  ? 51  ALA C CA    1 
ATOM   4743  C C     . ALA C 1 80  ? 85.009  179.250 141.320 1.00 36.20  ? 51  ALA C C     1 
ATOM   4744  O O     . ALA C 1 80  ? 86.039  179.922 141.447 1.00 36.20  ? 51  ALA C O     1 
ATOM   4745  C CB    . ALA C 1 80  ? 83.531  178.838 143.302 1.00 36.20  ? 51  ALA C CB    1 
ATOM   4746  N N     . ALA C 1 81  ? 84.964  178.156 140.560 1.00 34.21  ? 52  ALA C N     1 
ATOM   4747  C CA    . ALA C 1 81  ? 86.125  177.734 139.790 1.00 34.21  ? 52  ALA C CA    1 
ATOM   4748  C C     . ALA C 1 81  ? 86.478  178.744 138.710 1.00 34.21  ? 52  ALA C C     1 
ATOM   4749  O O     . ALA C 1 81  ? 87.659  178.942 138.420 1.00 34.21  ? 52  ALA C O     1 
ATOM   4750  C CB    . ALA C 1 81  ? 85.867  176.364 139.170 1.00 34.21  ? 52  ALA C CB    1 
ATOM   4751  N N     . GLY C 1 82  ? 85.480  179.388 138.105 1.00 36.23  ? 53  GLY C N     1 
ATOM   4752  C CA    . GLY C 1 82  ? 85.771  180.441 137.145 1.00 36.23  ? 53  GLY C CA    1 
ATOM   4753  C C     . GLY C 1 82  ? 86.464  181.629 137.782 1.00 36.23  ? 53  GLY C C     1 
ATOM   4754  O O     . GLY C 1 82  ? 87.403  182.197 137.212 1.00 36.23  ? 53  GLY C O     1 
ATOM   4755  N N     . LEU C 1 83  ? 86.009  182.019 138.976 1.00 38.39  ? 54  LEU C N     1 
ATOM   4756  C CA    . LEU C 1 83  ? 86.681  183.096 139.703 1.00 38.39  ? 54  LEU C CA    1 
ATOM   4757  C C     . LEU C 1 83  ? 88.113  182.709 140.054 1.00 38.39  ? 54  LEU C C     1 
ATOM   4758  O O     . LEU C 1 83  ? 89.034  183.527 139.938 1.00 38.39  ? 54  LEU C O     1 
ATOM   4759  C CB    . LEU C 1 83  ? 85.913  183.466 140.975 1.00 38.39  ? 54  LEU C CB    1 
ATOM   4760  C CG    . LEU C 1 83  ? 85.206  184.822 140.945 1.00 38.39  ? 54  LEU C CG    1 
ATOM   4761  C CD1   . LEU C 1 83  ? 84.129  184.855 139.869 1.00 38.39  ? 54  LEU C CD1   1 
ATOM   4762  C CD2   . LEU C 1 83  ? 84.618  185.140 142.307 1.00 38.39  ? 54  LEU C CD2   1 
ATOM   4763  N N     . VAL C 1 84  ? 88.324  181.459 140.467 1.00 36.54  ? 55  VAL C N     1 
ATOM   4764  C CA    . VAL C 1 84  ? 89.675  181.015 140.795 1.00 36.54  ? 55  VAL C CA    1 
ATOM   4765  C C     . VAL C 1 84  ? 90.546  180.972 139.543 1.00 36.54  ? 55  VAL C C     1 
ATOM   4766  O O     . VAL C 1 84  ? 91.742  181.263 139.606 1.00 36.54  ? 55  VAL C O     1 
ATOM   4767  C CB    . VAL C 1 84  ? 89.636  179.656 141.521 1.00 36.54  ? 55  VAL C CB    1 
ATOM   4768  C CG1   . VAL C 1 84  ? 91.041  179.050 141.633 1.00 36.54  ? 55  VAL C CG1   1 
ATOM   4769  C CG2   . VAL C 1 84  ? 89.034  179.828 142.912 1.00 36.54  ? 55  VAL C CG2   1 
ATOM   4770  N N     . VAL C 1 85  ? 89.971  180.606 138.394 1.00 37.97  ? 56  VAL C N     1 
ATOM   4771  C CA    . VAL C 1 85  ? 90.724  180.600 137.140 1.00 37.97  ? 56  VAL C CA    1 
ATOM   4772  C C     . VAL C 1 85  ? 91.154  182.015 136.778 1.00 37.97  ? 56  VAL C C     1 
ATOM   4773  O O     . VAL C 1 85  ? 92.290  182.245 136.340 1.00 37.97  ? 56  VAL C O     1 
ATOM   4774  C CB    . VAL C 1 85  ? 89.882  179.947 136.023 1.00 37.97  ? 56  VAL C CB    1 
ATOM   4775  C CG1   . VAL C 1 85  ? 90.381  180.315 134.614 1.00 37.97  ? 56  VAL C CG1   1 
ATOM   4776  C CG2   . VAL C 1 85  ? 89.890  178.445 136.180 1.00 37.97  ? 56  VAL C CG2   1 
ATOM   4777  N N     . ASP C 1 86  ? 90.247  182.982 136.943 1.00 42.26  ? 57  ASP C N     1 
ATOM   4778  C CA    . ASP C 1 86  ? 90.619  184.380 136.747 1.00 42.26  ? 57  ASP C CA    1 
ATOM   4779  C C     . ASP C 1 86  ? 91.702  184.811 137.726 1.00 42.26  ? 57  ASP C C     1 
ATOM   4780  O O     . ASP C 1 86  ? 92.553  185.639 137.384 1.00 42.26  ? 57  ASP C O     1 
ATOM   4781  C CB    . ASP C 1 86  ? 89.392  185.279 136.896 1.00 42.26  ? 57  ASP C CB    1 
ATOM   4782  C CG    . ASP C 1 86  ? 88.332  185.004 135.848 1.00 42.26  ? 57  ASP C CG    1 
ATOM   4783  O OD1   . ASP C 1 86  ? 88.683  184.515 134.754 1.00 42.26  ? 57  ASP C OD1   1 
ATOM   4784  O OD2   . ASP C 1 86  ? 87.145  185.278 136.119 1.00 42.26  ? 57  ASP C OD2   1 
ATOM   4785  N N     . MET C 1 87  ? 91.690  184.258 138.940 1.00 41.65  ? 58  MET C N     1 
ATOM   4786  C CA    . MET C 1 87  ? 92.729  184.585 139.911 1.00 41.65  ? 58  MET C CA    1 
ATOM   4787  C C     . MET C 1 87  ? 94.076  183.960 139.538 1.00 41.65  ? 58  MET C C     1 
ATOM   4788  O O     . MET C 1 87  ? 95.122  184.560 139.807 1.00 41.65  ? 58  MET C O     1 
ATOM   4789  C CB    . MET C 1 87  ? 92.274  184.150 141.309 1.00 41.65  ? 58  MET C CB    1 
ATOM   4790  C CG    . MET C 1 87  ? 91.272  185.130 141.955 1.00 41.65  ? 58  MET C CG    1 
ATOM   4791  S SD    . MET C 1 87  ? 90.930  185.027 143.727 1.00 41.65  ? 58  MET C SD    1 
ATOM   4792  C CE    . MET C 1 87  ? 91.100  183.286 144.045 1.00 41.65  ? 58  MET C CE    1 
ATOM   4793  N N     . ILE C 1 88  ? 94.079  182.768 138.928 1.00 39.58  ? 59  ILE C N     1 
ATOM   4794  C CA    . ILE C 1 88  ? 95.335  182.188 138.441 1.00 39.58  ? 59  ILE C CA    1 
ATOM   4795  C C     . ILE C 1 88  ? 95.868  182.985 137.260 1.00 39.58  ? 59  ILE C C     1 
ATOM   4796  O O     . ILE C 1 88  ? 97.087  183.128 137.102 1.00 39.58  ? 59  ILE C O     1 
ATOM   4797  C CB    . ILE C 1 88  ? 95.182  180.699 138.045 1.00 39.58  ? 59  ILE C CB    1 
ATOM   4798  C CG1   . ILE C 1 88  ? 94.637  179.797 139.179 1.00 39.58  ? 59  ILE C CG1   1 
ATOM   4799  C CG2   . ILE C 1 88  ? 96.536  180.168 137.469 1.00 39.58  ? 59  ILE C CG2   1 
ATOM   4800  C CD1   . ILE C 1 88  ? 95.038  180.155 140.569 1.00 39.58  ? 59  ILE C CD1   1 
ATOM   4801  N N     . LYS C 1 89  ? 94.976  183.468 136.388 1.00 42.80  ? 60  LYS C N     1 
ATOM   4802  C CA    . LYS C 1 89  ? 95.421  184.125 135.159 1.00 42.80  ? 60  LYS C CA    1 
ATOM   4803  C C     . LYS C 1 89  ? 96.219  185.396 135.432 1.00 42.80  ? 60  LYS C C     1 
ATOM   4804  O O     . LYS C 1 89  ? 97.090  185.754 134.631 1.00 42.80  ? 60  LYS C O     1 
ATOM   4805  C CB    . LYS C 1 89  ? 94.221  184.444 134.269 1.00 42.80  ? 60  LYS C CB    1 
ATOM   4806  C CG    . LYS C 1 89  ? 93.579  183.219 133.632 1.00 42.80  ? 60  LYS C CG    1 
ATOM   4807  C CD    . LYS C 1 89  ? 93.894  183.130 132.143 1.00 42.80  ? 60  LYS C CD    1 
ATOM   4808  C CE    . LYS C 1 89  ? 93.162  181.977 131.481 1.00 42.80  ? 60  LYS C CE    1 
ATOM   4809  N NZ    . LYS C 1 89  ? 91.764  182.342 131.129 1.00 42.80  ? 60  LYS C NZ    1 
ATOM   4810  N N     . GLN C 1 90  ? 95.947  186.076 136.552 1.00 46.86  ? 61  GLN C N     1 
ATOM   4811  C CA    . GLN C 1 90  ? 96.658  187.282 136.971 1.00 46.86  ? 61  GLN C CA    1 
ATOM   4812  C C     . GLN C 1 90  ? 97.468  187.077 138.253 1.00 46.86  ? 61  GLN C C     1 
ATOM   4813  O O     . GLN C 1 90  ? 97.810  188.056 138.923 1.00 46.86  ? 61  GLN C O     1 
ATOM   4814  C CB    . GLN C 1 90  ? 95.689  188.462 137.126 1.00 46.86  ? 61  GLN C CB    1 
ATOM   4815  C CG    . GLN C 1 90  ? 94.545  188.541 136.089 1.00 46.86  ? 61  GLN C CG    1 
ATOM   4816  C CD    . GLN C 1 90  ? 93.557  189.642 136.383 1.00 46.86  ? 61  GLN C CD    1 
ATOM   4817  O OE1   . GLN C 1 90  ? 93.854  190.585 137.117 1.00 46.86  ? 61  GLN C OE1   1 
ATOM   4818  N NE2   . GLN C 1 90  ? 92.377  189.545 135.783 1.00 46.86  ? 61  GLN C NE2   1 
ATOM   4819  N N     . LYS C 1 91  ? 97.780  185.824 138.606 1.00 47.60  ? 62  LYS C N     1 
ATOM   4820  C CA    . LYS C 1 91  ? 98.842  185.490 139.563 1.00 47.60  ? 62  LYS C CA    1 
ATOM   4821  C C     . LYS C 1 91  ? 98.556  186.007 140.973 1.00 47.60  ? 62  LYS C C     1 
ATOM   4822  O O     . LYS C 1 91  ? 99.485  186.303 141.729 1.00 47.60  ? 62  LYS C O     1 
ATOM   4823  C CB    . LYS C 1 91  ? 100.214 186.004 139.093 1.00 47.60  ? 62  LYS C CB    1 
ATOM   4824  C CG    . LYS C 1 91  ? 100.628 185.657 137.631 1.00 47.60  ? 62  LYS C CG    1 
ATOM   4825  C CD    . LYS C 1 91  ? 101.257 184.257 137.396 1.00 47.60  ? 62  LYS C CD    1 
ATOM   4826  C CE    . LYS C 1 91  ? 102.465 183.888 138.267 1.00 47.60  ? 62  LYS C CE    1 
ATOM   4827  N NZ    . LYS C 1 91  ? 102.912 182.494 137.996 1.00 47.60  ? 62  LYS C NZ    1 
ATOM   4828  N N     . LYS C 1 92  ? 97.280  186.106 141.348 1.00 45.08  ? 63  LYS C N     1 
ATOM   4829  C CA    . LYS C 1 92  ? 96.893  186.519 142.693 1.00 45.08  ? 63  LYS C CA    1 
ATOM   4830  C C     . LYS C 1 92  ? 96.785  185.357 143.678 1.00 45.08  ? 63  LYS C C     1 
ATOM   4831  O O     . LYS C 1 92  ? 96.707  185.604 144.887 1.00 45.08  ? 63  LYS C O     1 
ATOM   4832  C CB    . LYS C 1 92  ? 95.562  187.277 142.650 1.00 45.08  ? 63  LYS C CB    1 
ATOM   4833  C CG    . LYS C 1 92  ? 95.427  188.246 141.484 1.00 45.08  ? 63  LYS C CG    1 
ATOM   4834  C CD    . LYS C 1 92  ? 94.234  189.164 141.671 1.00 45.08  ? 63  LYS C CD    1 
ATOM   4835  C CE    . LYS C 1 92  ? 94.599  190.417 142.451 1.00 45.08  ? 63  LYS C CE    1 
ATOM   4836  N NZ    . LYS C 1 92  ? 95.057  191.525 141.568 1.00 45.08  ? 63  LYS C NZ    1 
ATOM   4837  N N     . MET C 1 93  ? 96.775  184.111 143.200 1.00 42.03  ? 64  MET C N     1 
ATOM   4838  C CA    . MET C 1 93  ? 96.804  182.917 144.039 1.00 42.03  ? 64  MET C CA    1 
ATOM   4839  C C     . MET C 1 93  ? 98.225  182.446 144.366 1.00 42.03  ? 64  MET C C     1 
ATOM   4840  O O     . MET C 1 93  ? 98.389  181.378 144.966 1.00 42.03  ? 64  MET C O     1 
ATOM   4841  C CB    . MET C 1 93  ? 95.996  181.803 143.343 1.00 42.03  ? 64  MET C CB    1 
ATOM   4842  C CG    . MET C 1 93  ? 95.689  180.554 144.183 1.00 42.03  ? 64  MET C CG    1 
ATOM   4843  S SD    . MET C 1 93  ? 94.120  179.704 143.945 1.00 42.03  ? 64  MET C SD    1 
ATOM   4844  C CE    . MET C 1 93  ? 93.015  180.659 144.958 1.00 42.03  ? 64  MET C CE    1 
ATOM   4845  N N     . ALA C 1 94  ? 99.260  183.209 144.003 1.00 40.36  ? 65  ALA C N     1 
ATOM   4846  C CA    . ALA C 1 94  ? 100.625 182.844 144.364 1.00 40.36  ? 65  ALA C CA    1 
ATOM   4847  C C     . ALA C 1 94  ? 100.794 182.849 145.878 1.00 40.36  ? 65  ALA C C     1 
ATOM   4848  O O     . ALA C 1 94  ? 100.735 183.909 146.508 1.00 40.36  ? 65  ALA C O     1 
ATOM   4849  C CB    . ALA C 1 94  ? 101.627 183.800 143.715 1.00 40.36  ? 65  ALA C CB    1 
ATOM   4850  N N     . GLY C 1 95  ? 100.993 181.662 146.457 1.00 38.15  ? 66  GLY C N     1 
ATOM   4851  C CA    . GLY C 1 95  ? 101.115 181.465 147.890 1.00 38.15  ? 66  GLY C CA    1 
ATOM   4852  C C     . GLY C 1 95  ? 99.950  180.749 148.542 1.00 38.15  ? 66  GLY C C     1 
ATOM   4853  O O     . GLY C 1 95  ? 100.085 180.340 149.702 1.00 38.15  ? 66  GLY C O     1 
ATOM   4854  N N     . LYS C 1 96  ? 98.818  180.585 147.851 1.00 39.79  ? 67  LYS C N     1 
ATOM   4855  C CA    . LYS C 1 96  ? 97.633  179.899 148.354 1.00 39.79  ? 67  LYS C CA    1 
ATOM   4856  C C     . LYS C 1 96  ? 97.394  178.622 147.551 1.00 39.79  ? 67  LYS C C     1 
ATOM   4857  O O     . LYS C 1 96  ? 98.144  178.283 146.632 1.00 39.79  ? 67  LYS C O     1 
ATOM   4858  C CB    . LYS C 1 96  ? 96.407  180.814 148.289 1.00 39.79  ? 67  LYS C CB    1 
ATOM   4859  C CG    . LYS C 1 96  ? 96.660  182.269 148.645 1.00 39.79  ? 67  LYS C CG    1 
ATOM   4860  C CD    . LYS C 1 96  ? 95.342  183.013 148.803 1.00 39.79  ? 67  LYS C CD    1 
ATOM   4861  C CE    . LYS C 1 96  ? 95.452  184.481 148.421 1.00 39.79  ? 67  LYS C CE    1 
ATOM   4862  N NZ    . LYS C 1 96  ? 95.628  184.688 146.957 1.00 39.79  ? 67  LYS C NZ    1 
ATOM   4863  N N     . ALA C 1 97  ? 96.329  177.911 147.917 1.00 37.88  ? 68  ALA C N     1 
ATOM   4864  C CA    . ALA C 1 97  ? 95.947  176.666 147.265 1.00 37.88  ? 68  ALA C CA    1 
ATOM   4865  C C     . ALA C 1 97  ? 94.434  176.532 147.351 1.00 37.88  ? 68  ALA C C     1 
ATOM   4866  O O     . ALA C 1 97  ? 93.772  177.269 148.083 1.00 37.88  ? 68  ALA C O     1 
ATOM   4867  C CB    . ALA C 1 97  ? 96.645  175.463 147.905 1.00 37.88  ? 68  ALA C CB    1 
ATOM   4868  N N     . LEU C 1 98  ? 93.892  175.580 146.589 1.00 32.37  ? 69  LEU C N     1 
ATOM   4869  C CA    . LEU C 1 98  ? 92.455  175.365 146.476 1.00 32.37  ? 69  LEU C CA    1 
ATOM   4870  C C     . LEU C 1 98  ? 92.107  174.056 147.174 1.00 32.37  ? 69  LEU C C     1 
ATOM   4871  O O     . LEU C 1 98  ? 92.907  173.120 147.167 1.00 32.37  ? 69  LEU C O     1 
ATOM   4872  C CB    . LEU C 1 98  ? 92.052  175.318 144.998 1.00 32.37  ? 69  LEU C CB    1 
ATOM   4873  C CG    . LEU C 1 98  ? 90.631  175.684 144.546 1.00 32.37  ? 69  LEU C CG    1 
ATOM   4874  C CD1   . LEU C 1 98  ? 90.535  175.703 143.022 1.00 32.37  ? 69  LEU C CD1   1 
ATOM   4875  C CD2   . LEU C 1 98  ? 89.573  174.760 145.100 1.00 32.37  ? 69  LEU C CD2   1 
ATOM   4876  N N     . LEU C 1 99  ? 90.938  174.008 147.815 1.00 34.68  ? 70  LEU C N     1 
ATOM   4877  C CA    . LEU C 1 99  ? 90.387  172.779 148.383 1.00 34.68  ? 70  LEU C CA    1 
ATOM   4878  C C     . LEU C 1 99  ? 88.942  172.637 147.933 1.00 34.68  ? 70  LEU C C     1 
ATOM   4879  O O     . LEU C 1 99  ? 88.169  173.596 148.010 1.00 34.68  ? 70  LEU C O     1 
ATOM   4880  C CB    . LEU C 1 99  ? 90.487  172.770 149.919 1.00 34.68  ? 70  LEU C CB    1 
ATOM   4881  C CG    . LEU C 1 99  ? 89.841  171.628 150.729 1.00 34.68  ? 70  LEU C CG    1 
ATOM   4882  C CD1   . LEU C 1 99  ? 90.523  170.307 150.500 1.00 34.68  ? 70  LEU C CD1   1 
ATOM   4883  C CD2   . LEU C 1 99  ? 89.887  171.939 152.208 1.00 34.68  ? 70  LEU C CD2   1 
ATOM   4884  N N     . LEU C 1 100 ? 88.591  171.439 147.460 1.00 30.79  ? 71  LEU C N     1 
ATOM   4885  C CA    . LEU C 1 100 ? 87.231  171.078 147.070 1.00 30.79  ? 71  LEU C CA    1 
ATOM   4886  C C     . LEU C 1 100 ? 86.673  170.146 148.138 1.00 30.79  ? 71  LEU C C     1 
ATOM   4887  O O     . LEU C 1 100 ? 87.078  168.981 148.225 1.00 30.79  ? 71  LEU C O     1 
ATOM   4888  C CB    . LEU C 1 100 ? 87.215  170.409 145.698 1.00 30.79  ? 71  LEU C CB    1 
ATOM   4889  C CG    . LEU C 1 100 ? 87.825  171.185 144.529 1.00 30.79  ? 71  LEU C CG    1 
ATOM   4890  C CD1   . LEU C 1 100 ? 87.823  170.332 143.278 1.00 30.79  ? 71  LEU C CD1   1 
ATOM   4891  C CD2   . LEU C 1 100 ? 87.077  172.473 144.281 1.00 30.79  ? 71  LEU C CD2   1 
ATOM   4892  N N     . ALA C 1 101 ? 85.739  170.658 148.938 1.00 35.45  ? 72  ALA C N     1 
ATOM   4893  C CA    . ALA C 1 101 ? 85.125  169.914 150.034 1.00 35.45  ? 72  ALA C CA    1 
ATOM   4894  C C     . ALA C 1 101 ? 83.724  169.503 149.605 1.00 35.45  ? 72  ALA C C     1 
ATOM   4895  O O     . ALA C 1 101 ? 82.845  170.354 149.446 1.00 35.45  ? 72  ALA C O     1 
ATOM   4896  C CB    . ALA C 1 101 ? 85.083  170.764 151.300 1.00 35.45  ? 72  ALA C CB    1 
ATOM   4897  N N     . GLY C 1 102 ? 83.513  168.202 149.415 1.00 35.48  ? 73  GLY C N     1 
ATOM   4898  C CA    . GLY C 1 102 ? 82.200  167.718 149.059 1.00 35.48  ? 73  GLY C CA    1 
ATOM   4899  C C     . GLY C 1 102 ? 82.092  166.206 149.048 1.00 35.48  ? 73  GLY C C     1 
ATOM   4900  O O     . GLY C 1 102 ? 83.099  165.508 149.179 1.00 35.48  ? 73  GLY C O     1 
ATOM   4901  N N     . PRO C 1 103 ? 80.882  165.663 148.888 1.00 36.43  ? 74  PRO C N     1 
ATOM   4902  C CA    . PRO C 1 103 ? 80.714  164.199 148.957 1.00 36.43  ? 74  PRO C CA    1 
ATOM   4903  C C     . PRO C 1 103 ? 81.365  163.496 147.778 1.00 36.43  ? 74  PRO C C     1 
ATOM   4904  O O     . PRO C 1 103 ? 81.824  164.154 146.833 1.00 36.43  ? 74  PRO C O     1 
ATOM   4905  C CB    . PRO C 1 103 ? 79.190  164.016 148.927 1.00 36.43  ? 74  PRO C CB    1 
ATOM   4906  C CG    . PRO C 1 103 ? 78.642  165.309 149.350 1.00 36.43  ? 74  PRO C CG    1 
ATOM   4907  C CD    . PRO C 1 103 ? 79.568  166.329 148.787 1.00 36.43  ? 74  PRO C CD    1 
ATOM   4908  N N     . PRO C 1 104 ? 81.396  162.152 147.754 1.00 34.38  ? 75  PRO C N     1 
ATOM   4909  C CA    . PRO C 1 104 ? 81.935  161.452 146.608 1.00 34.38  ? 75  PRO C CA    1 
ATOM   4910  C C     . PRO C 1 104 ? 81.026  161.624 145.416 1.00 34.38  ? 75  PRO C C     1 
ATOM   4911  O O     . PRO C 1 104 ? 79.869  162.019 145.603 1.00 34.38  ? 75  PRO C O     1 
ATOM   4912  C CB    . PRO C 1 104 ? 81.997  160.010 147.088 1.00 34.38  ? 75  PRO C CB    1 
ATOM   4913  C CG    . PRO C 1 104 ? 81.919  160.104 148.591 1.00 34.38  ? 75  PRO C CG    1 
ATOM   4914  C CD    . PRO C 1 104 ? 80.994  161.273 148.824 1.00 34.38  ? 75  PRO C CD    1 
ATOM   4915  N N     . GLY C 1 105 ? 81.520  161.326 144.218 1.00 33.80  ? 76  GLY C N     1 
ATOM   4916  C CA    . GLY C 1 105 ? 80.728  161.431 142.984 1.00 33.80  ? 76  GLY C CA    1 
ATOM   4917  C C     . GLY C 1 105 ? 80.033  162.766 142.887 1.00 33.80  ? 76  GLY C C     1 
ATOM   4918  O O     . GLY C 1 105 ? 78.849  162.763 142.506 1.00 33.80  ? 76  GLY C O     1 
ATOM   4919  N N     . THR C 1 106 ? 80.716  163.868 143.214 1.00 31.87  ? 77  THR C N     1 
ATOM   4920  C CA    . THR C 1 106 ? 80.156  165.213 143.128 1.00 31.87  ? 77  THR C CA    1 
ATOM   4921  C C     . THR C 1 106 ? 80.926  166.107 142.154 1.00 31.87  ? 77  THR C C     1 
ATOM   4922  O O     . THR C 1 106 ? 80.766  167.330 142.183 1.00 31.87  ? 77  THR C O     1 
ATOM   4923  C CB    . THR C 1 106 ? 80.128  165.835 144.524 1.00 31.87  ? 77  THR C CB    1 
ATOM   4924  O OG1   . THR C 1 106 ? 79.861  164.805 145.481 1.00 31.87  ? 77  THR C OG1   1 
ATOM   4925  C CG2   . THR C 1 106 ? 79.030  166.892 144.656 1.00 31.87  ? 77  THR C CG2   1 
ATOM   4926  N N     . GLY C 1 107 ? 81.758  165.531 141.287 1.00 30.90  ? 78  GLY C N     1 
ATOM   4927  C CA    . GLY C 1 107 ? 82.409  166.316 140.259 1.00 30.90  ? 78  GLY C CA    1 
ATOM   4928  C C     . GLY C 1 107 ? 83.584  167.143 140.722 1.00 30.90  ? 78  GLY C C     1 
ATOM   4929  O O     . GLY C 1 107 ? 83.885  168.168 140.106 1.00 30.90  ? 78  GLY C O     1 
ATOM   4930  N N     . LYS C 1 108 ? 84.262  166.732 141.795 1.00 31.27  ? 79  LYS C N     1 
ATOM   4931  C CA    . LYS C 1 108 ? 85.440  167.468 142.245 1.00 31.27  ? 79  LYS C CA    1 
ATOM   4932  C C     . LYS C 1 108 ? 86.595  167.294 141.266 1.00 31.27  ? 79  LYS C C     1 
ATOM   4933  O O     . LYS C 1 108 ? 87.237  168.273 140.862 1.00 31.27  ? 79  LYS C O     1 
ATOM   4934  C CB    . LYS C 1 108 ? 85.849  167.012 143.646 1.00 31.27  ? 79  LYS C CB    1 
ATOM   4935  C CG    . LYS C 1 108 ? 84.706  166.967 144.659 1.00 31.27  ? 79  LYS C CG    1 
ATOM   4936  C CD    . LYS C 1 108 ? 85.191  166.814 146.096 1.00 31.27  ? 79  LYS C CD    1 
ATOM   4937  C CE    . LYS C 1 108 ? 85.703  165.416 146.399 1.00 31.27  ? 79  LYS C CE    1 
ATOM   4938  N NZ    . LYS C 1 108 ? 84.606  164.419 146.452 1.00 31.27  ? 79  LYS C NZ    1 
ATOM   4939  N N     . THR C 1 109 ? 86.853  166.067 140.819 1.00 33.90  ? 80  THR C N     1 
ATOM   4940  C CA    . THR C 1 109 ? 87.939  165.778 139.867 1.00 33.90  ? 80  THR C CA    1 
ATOM   4941  C C     . THR C 1 109 ? 87.543  166.339 138.537 1.00 33.90  ? 80  THR C C     1 
ATOM   4942  O O     . THR C 1 109 ? 88.453  166.704 137.809 1.00 33.90  ? 80  THR C O     1 
ATOM   4943  C CB    . THR C 1 109 ? 88.216  164.284 139.781 1.00 33.90  ? 80  THR C CB    1 
ATOM   4944  O OG1   . THR C 1 109 ? 88.551  163.884 141.105 1.00 33.90  ? 80  THR C OG1   1 
ATOM   4945  C CG2   . THR C 1 109 ? 89.368  163.958 138.848 1.00 33.90  ? 80  THR C CG2   1 
ATOM   4946  N N     . ALA C 1 110 ? 86.262  166.339 138.178 1.00 33.20  ? 81  ALA C N     1 
ATOM   4947  C CA    . ALA C 1 110 ? 85.799  166.992 136.960 1.00 33.20  ? 81  ALA C CA    1 
ATOM   4948  C C     . ALA C 1 110 ? 85.994  168.498 137.043 1.00 33.20  ? 81  ALA C C     1 
ATOM   4949  O O     . ALA C 1 110 ? 86.362  169.138 136.053 1.00 33.20  ? 81  ALA C O     1 
ATOM   4950  C CB    . ALA C 1 110 ? 84.330  166.656 136.713 1.00 33.20  ? 81  ALA C CB    1 
ATOM   4951  N N     . LEU C 1 111 ? 85.758  169.081 138.220 1.00 32.42  ? 82  LEU C N     1 
ATOM   4952  C CA    . LEU C 1 111 ? 85.971  170.517 138.392 1.00 32.42  ? 82  LEU C CA    1 
ATOM   4953  C C     . LEU C 1 111 ? 87.441  170.881 138.239 1.00 32.42  ? 82  LEU C C     1 
ATOM   4954  O O     . LEU C 1 111 ? 87.772  171.897 137.618 1.00 32.42  ? 82  LEU C O     1 
ATOM   4955  C CB    . LEU C 1 111 ? 85.470  170.984 139.762 1.00 32.42  ? 82  LEU C CB    1 
ATOM   4956  C CG    . LEU C 1 111 ? 84.143  171.749 139.832 1.00 32.42  ? 82  LEU C CG    1 
ATOM   4957  C CD1   . LEU C 1 111 ? 83.715  172.003 141.281 1.00 32.42  ? 82  LEU C CD1   1 
ATOM   4958  C CD2   . LEU C 1 111 ? 84.213  173.076 139.075 1.00 32.42  ? 82  LEU C CD2   1 
ATOM   4959  N N     . ALA C 1 112 ? 88.335  170.075 138.815 1.00 33.34  ? 83  ALA C N     1 
ATOM   4960  C CA    . ALA C 1 112 ? 89.763  170.346 138.678 1.00 33.34  ? 83  ALA C CA    1 
ATOM   4961  C C     . ALA C 1 112 ? 90.211  170.220 137.228 1.00 33.34  ? 83  ALA C C     1 
ATOM   4962  O O     . ALA C 1 112 ? 91.016  171.027 136.744 1.00 33.34  ? 83  ALA C O     1 
ATOM   4963  C CB    . ALA C 1 112 ? 90.562  169.400 139.566 1.00 33.34  ? 83  ALA C CB    1 
ATOM   4964  N N     . LEU C 1 113 ? 89.699  169.212 136.518 1.00 33.53  ? 84  LEU C N     1 
ATOM   4965  C CA    . LEU C 1 113 ? 90.035  169.066 135.106 1.00 33.53  ? 84  LEU C CA    1 
ATOM   4966  C C     . LEU C 1 113 ? 89.490  170.233 134.294 1.00 33.53  ? 84  LEU C C     1 
ATOM   4967  O O     . LEU C 1 113 ? 90.144  170.705 133.358 1.00 33.53  ? 84  LEU C O     1 
ATOM   4968  C CB    . LEU C 1 113 ? 89.504  167.737 134.565 1.00 33.53  ? 84  LEU C CB    1 
ATOM   4969  C CG    . LEU C 1 113 ? 90.390  167.036 133.529 1.00 33.53  ? 84  LEU C CG    1 
ATOM   4970  C CD1   . LEU C 1 113 ? 89.919  165.609 133.307 1.00 33.53  ? 84  LEU C CD1   1 
ATOM   4971  C CD2   . LEU C 1 113 ? 90.433  167.802 132.212 1.00 33.53  ? 84  LEU C CD2   1 
ATOM   4972  N N     . GLY C 1 114 ? 88.301  170.723 134.648 1.00 32.77  ? 85  GLY C N     1 
ATOM   4973  C CA    . GLY C 1 114 ? 87.766  171.894 133.977 1.00 32.77  ? 85  GLY C CA    1 
ATOM   4974  C C     . GLY C 1 114 ? 88.602  173.135 134.221 1.00 32.77  ? 85  GLY C C     1 
ATOM   4975  O O     . GLY C 1 114 ? 88.804  173.943 133.314 1.00 32.77  ? 85  GLY C O     1 
ATOM   4976  N N     . ILE C 1 115 ? 89.103  173.298 135.448 1.00 32.85  ? 86  ILE C N     1 
ATOM   4977  C CA    . ILE C 1 115 ? 89.983  174.424 135.762 1.00 32.85  ? 86  ILE C CA    1 
ATOM   4978  C C     . ILE C 1 115 ? 91.261  174.336 134.937 1.00 32.85  ? 86  ILE C C     1 
ATOM   4979  O O     . ILE C 1 115 ? 91.709  175.327 134.343 1.00 32.85  ? 86  ILE C O     1 
ATOM   4980  C CB    . ILE C 1 115 ? 90.281  174.463 137.276 1.00 32.85  ? 86  ILE C CB    1 
ATOM   4981  C CG1   . ILE C 1 115 ? 89.052  174.945 138.049 1.00 32.85  ? 86  ILE C CG1   1 
ATOM   4982  C CG2   . ILE C 1 115 ? 91.476  175.375 137.606 1.00 32.85  ? 86  ILE C CG2   1 
ATOM   4983  C CD1   . ILE C 1 115 ? 89.008  174.498 139.500 1.00 32.85  ? 86  ILE C CD1   1 
ATOM   4984  N N     . SER C 1 116 ? 91.860  173.142 134.882 1.00 34.45  ? 87  SER C N     1 
ATOM   4985  C CA    . SER C 1 116 ? 93.103  172.967 134.135 1.00 34.45  ? 87  SER C CA    1 
ATOM   4986  C C     . SER C 1 116 ? 92.891  173.203 132.646 1.00 34.45  ? 87  SER C C     1 
ATOM   4987  O O     . SER C 1 116 ? 93.757  173.767 131.970 1.00 34.45  ? 87  SER C O     1 
ATOM   4988  C CB    . SER C 1 116 ? 93.670  171.570 134.375 1.00 34.45  ? 87  SER C CB    1 
ATOM   4989  O OG    . SER C 1 116 ? 93.132  170.645 133.449 1.00 34.45  ? 87  SER C OG    1 
ATOM   4990  N N     . GLN C 1 117 ? 91.742  172.778 132.116 1.00 34.87  ? 88  GLN C N     1 
ATOM   4991  C CA    . GLN C 1 117 ? 91.430  173.050 130.717 1.00 34.87  ? 88  GLN C CA    1 
ATOM   4992  C C     . GLN C 1 117 ? 91.213  174.539 130.480 1.00 34.87  ? 88  GLN C C     1 
ATOM   4993  O O     . GLN C 1 117 ? 91.640  175.078 129.453 1.00 34.87  ? 88  GLN C O     1 
ATOM   4994  C CB    . GLN C 1 117 ? 90.195  172.256 130.287 1.00 34.87  ? 88  GLN C CB    1 
ATOM   4995  C CG    . GLN C 1 117 ? 90.367  170.741 130.302 1.00 34.87  ? 88  GLN C CG    1 
ATOM   4996  C CD    . GLN C 1 117 ? 90.755  170.185 128.949 1.00 34.87  ? 88  GLN C CD    1 
ATOM   4997  O OE1   . GLN C 1 117 ? 91.551  170.782 128.226 1.00 34.87  ? 88  GLN C OE1   1 
ATOM   4998  N NE2   . GLN C 1 117 ? 90.198  169.031 128.601 1.00 34.87  ? 88  GLN C NE2   1 
ATOM   4999  N N     . GLU C 1 118 ? 90.551  175.221 131.416 1.00 37.08  ? 89  GLU C N     1 
ATOM   5000  C CA    . GLU C 1 118 ? 90.275  176.643 131.251 1.00 37.08  ? 89  GLU C CA    1 
ATOM   5001  C C     . GLU C 1 118 ? 91.528  177.499 131.368 1.00 37.08  ? 89  GLU C C     1 
ATOM   5002  O O     . GLU C 1 118 ? 91.541  178.616 130.842 1.00 37.08  ? 89  GLU C O     1 
ATOM   5003  C CB    . GLU C 1 118 ? 89.248  177.108 132.285 1.00 37.08  ? 89  GLU C CB    1 
ATOM   5004  C CG    . GLU C 1 118 ? 88.359  178.252 131.806 1.00 37.08  ? 89  GLU C CG    1 
ATOM   5005  C CD    . GLU C 1 118 ? 87.239  177.803 130.880 1.00 37.08  ? 89  GLU C CD    1 
ATOM   5006  O OE1   . GLU C 1 118 ? 86.630  176.740 131.129 1.00 37.08  ? 89  GLU C OE1   1 
ATOM   5007  O OE2   . GLU C 1 118 ? 86.963  178.520 129.896 1.00 37.08  ? 89  GLU C OE2   1 
ATOM   5008  N N     . LEU C 1 119 ? 92.565  177.018 132.062 1.00 37.82  ? 90  LEU C N     1 
ATOM   5009  C CA    . LEU C 1 119 ? 93.797  177.796 132.167 1.00 37.82  ? 90  LEU C CA    1 
ATOM   5010  C C     . LEU C 1 119 ? 94.458  177.985 130.806 1.00 37.82  ? 90  LEU C C     1 
ATOM   5011  O O     . LEU C 1 119 ? 94.954  179.075 130.498 1.00 37.82  ? 90  LEU C O     1 
ATOM   5012  C CB    . LEU C 1 119 ? 94.771  177.122 133.136 1.00 37.82  ? 90  LEU C CB    1 
ATOM   5013  C CG    . LEU C 1 119 ? 94.495  177.228 134.639 1.00 37.82  ? 90  LEU C CG    1 
ATOM   5014  C CD1   . LEU C 1 119 ? 95.446  176.325 135.412 1.00 37.82  ? 90  LEU C CD1   1 
ATOM   5015  C CD2   . LEU C 1 119 ? 94.615  178.655 135.139 1.00 37.82  ? 90  LEU C CD2   1 
ATOM   5016  N N     . GLY C 1 120 ? 94.475  176.947 129.981 1.00 43.18  ? 91  GLY C N     1 
ATOM   5017  C CA    . GLY C 1 120 ? 95.092  177.070 128.677 1.00 43.18  ? 91  GLY C CA    1 
ATOM   5018  C C     . GLY C 1 120 ? 94.853  175.841 127.830 1.00 43.18  ? 91  GLY C C     1 
ATOM   5019  O O     . GLY C 1 120 ? 94.065  174.961 128.182 1.00 43.18  ? 91  GLY C O     1 
ATOM   5020  N N     . SER C 1 121 ? 95.556  175.792 126.697 1.00 47.56  ? 92  SER C N     1 
ATOM   5021  C CA    . SER C 1 121 ? 95.315  174.741 125.713 1.00 47.56  ? 92  SER C CA    1 
ATOM   5022  C C     . SER C 1 121 ? 95.855  173.399 126.191 1.00 47.56  ? 92  SER C C     1 
ATOM   5023  O O     . SER C 1 121 ? 95.091  172.449 126.400 1.00 47.56  ? 92  SER C O     1 
ATOM   5024  C CB    . SER C 1 121 ? 95.949  175.129 124.377 1.00 47.56  ? 92  SER C CB    1 
ATOM   5025  O OG    . SER C 1 121 ? 97.329  175.404 124.535 1.00 47.56  ? 92  SER C OG    1 
ATOM   5026  N N     . LYS C 1 122 ? 97.173  173.310 126.376 1.00 48.09  ? 93  LYS C N     1 
ATOM   5027  C CA    . LYS C 1 122 ? 97.873  172.084 126.757 1.00 48.09  ? 93  LYS C CA    1 
ATOM   5028  C C     . LYS C 1 122 ? 98.442  172.198 128.166 1.00 48.09  ? 93  LYS C C     1 
ATOM   5029  O O     . LYS C 1 122 ? 99.561  171.762 128.441 1.00 48.09  ? 93  LYS C O     1 
ATOM   5030  C CB    . LYS C 1 122 ? 98.984  171.766 125.762 1.00 48.09  ? 93  LYS C CB    1 
ATOM   5031  C CG    . LYS C 1 122 ? 98.535  171.776 124.308 1.00 48.09  ? 93  LYS C CG    1 
ATOM   5032  C CD    . LYS C 1 122 ? 99.493  171.022 123.381 1.00 48.09  ? 93  LYS C CD    1 
ATOM   5033  C CE    . LYS C 1 122 ? 100.938 171.521 123.450 1.00 48.09  ? 93  LYS C CE    1 
ATOM   5034  N NZ    . LYS C 1 122 ? 101.057 172.994 123.255 1.00 48.09  ? 93  LYS C NZ    1 
ATOM   5035  N N     . VAL C 1 123 ? 97.675  172.792 129.067 1.00 41.44  ? 94  VAL C N     1 
ATOM   5036  C CA    . VAL C 1 123 ? 98.127  172.955 130.452 1.00 41.44  ? 94  VAL C CA    1 
ATOM   5037  C C     . VAL C 1 123 ? 98.140  171.581 131.125 1.00 41.44  ? 94  VAL C C     1 
ATOM   5038  O O     . VAL C 1 123 ? 97.127  170.864 131.049 1.00 41.44  ? 94  VAL C O     1 
ATOM   5039  C CB    . VAL C 1 123 ? 97.207  173.934 131.194 1.00 41.44  ? 94  VAL C CB    1 
ATOM   5040  C CG1   . VAL C 1 123 ? 97.496  173.942 132.688 1.00 41.44  ? 94  VAL C CG1   1 
ATOM   5041  C CG2   . VAL C 1 123 ? 97.363  175.344 130.619 1.00 41.44  ? 94  VAL C CG2   1 
ATOM   5042  N N     . PRO C 1 124 ? 99.229  171.143 131.772 1.00 44.23  ? 95  PRO C N     1 
ATOM   5043  C CA    . PRO C 1 124 ? 99.218  169.796 132.354 1.00 44.23  ? 95  PRO C CA    1 
ATOM   5044  C C     . PRO C 1 124 ? 98.293  169.686 133.555 1.00 44.23  ? 95  PRO C C     1 
ATOM   5045  O O     . PRO C 1 124 ? 97.987  170.671 134.230 1.00 44.23  ? 95  PRO C O     1 
ATOM   5046  C CB    . PRO C 1 124 ? 100.676 169.569 132.763 1.00 44.23  ? 95  PRO C CB    1 
ATOM   5047  C CG    . PRO C 1 124 ? 101.196 170.899 133.001 1.00 44.23  ? 95  PRO C CG    1 
ATOM   5048  C CD    . PRO C 1 124 ? 100.539 171.787 132.002 1.00 44.23  ? 95  PRO C CD    1 
ATOM   5049  N N     . PHE C 1 125 ? 97.852  168.454 133.809 1.00 35.95  ? 96  PHE C N     1 
ATOM   5050  C CA    . PHE C 1 125 ? 96.938  168.127 134.902 1.00 35.95  ? 96  PHE C CA    1 
ATOM   5051  C C     . PHE C 1 125 ? 97.418  166.828 135.529 1.00 35.95  ? 96  PHE C C     1 
ATOM   5052  O O     . PHE C 1 125 ? 97.297  165.766 134.912 1.00 35.95  ? 96  PHE C O     1 
ATOM   5053  C CB    . PHE C 1 125 ? 95.503  167.994 134.392 1.00 35.95  ? 96  PHE C CB    1 
ATOM   5054  C CG    . PHE C 1 125 ? 94.523  167.541 135.437 1.00 35.95  ? 96  PHE C CG    1 
ATOM   5055  C CD1   . PHE C 1 125 ? 94.199  168.353 136.505 1.00 35.95  ? 96  PHE C CD1   1 
ATOM   5056  C CD2   . PHE C 1 125 ? 93.918  166.303 135.342 1.00 35.95  ? 96  PHE C CD2   1 
ATOM   5057  C CE1   . PHE C 1 125 ? 93.297  167.937 137.463 1.00 35.95  ? 96  PHE C CE1   1 
ATOM   5058  C CE2   . PHE C 1 125 ? 93.018  165.881 136.301 1.00 35.95  ? 96  PHE C CE2   1 
ATOM   5059  C CZ    . PHE C 1 125 ? 92.707  166.700 137.359 1.00 35.95  ? 96  PHE C CZ    1 
ATOM   5060  N N     . CYS C 1 126 ? 97.951  166.911 136.751 1.00 37.76  ? 97  CYS C N     1 
ATOM   5061  C CA    . CYS C 1 126 ? 98.516  165.763 137.456 1.00 37.76  ? 97  CYS C CA    1 
ATOM   5062  C C     . CYS C 1 126 ? 97.572  165.341 138.577 1.00 37.76  ? 97  CYS C C     1 
ATOM   5063  O O     . CYS C 1 126 ? 97.594  165.950 139.659 1.00 37.76  ? 97  CYS C O     1 
ATOM   5064  C CB    . CYS C 1 126 ? 99.893  166.115 138.024 1.00 37.76  ? 97  CYS C CB    1 
ATOM   5065  S SG    . CYS C 1 126 ? 101.087 166.613 136.767 1.00 37.76  ? 97  CYS C SG    1 
ATOM   5066  N N     . PRO C 1 127 ? 96.703  164.346 138.373 1.00 35.96  ? 98  PRO C N     1 
ATOM   5067  C CA    . PRO C 1 127 ? 95.939  163.795 139.496 1.00 35.96  ? 98  PRO C CA    1 
ATOM   5068  C C     . PRO C 1 127 ? 96.740  162.770 140.277 1.00 35.96  ? 98  PRO C C     1 
ATOM   5069  O O     . PRO C 1 127 ? 97.603  162.071 139.742 1.00 35.96  ? 98  PRO C O     1 
ATOM   5070  C CB    . PRO C 1 127 ? 94.730  163.144 138.816 1.00 35.96  ? 98  PRO C CB    1 
ATOM   5071  C CG    . PRO C 1 127 ? 95.206  162.779 137.488 1.00 35.96  ? 98  PRO C CG    1 
ATOM   5072  C CD    . PRO C 1 127 ? 96.217  163.810 137.088 1.00 35.96  ? 98  PRO C CD    1 
ATOM   5073  N N     . MET C 1 128 ? 96.443  162.697 141.568 1.00 43.55  ? 99  MET C N     1 
ATOM   5074  C CA    . MET C 1 128 ? 97.075  161.719 142.439 1.00 43.55  ? 99  MET C CA    1 
ATOM   5075  C C     . MET C 1 128 ? 96.214  161.562 143.683 1.00 43.55  ? 99  MET C C     1 
ATOM   5076  O O     . MET C 1 128 ? 95.238  162.290 143.881 1.00 43.55  ? 99  MET C O     1 
ATOM   5077  C CB    . MET C 1 128 ? 98.511  162.131 142.786 1.00 43.55  ? 99  MET C CB    1 
ATOM   5078  C CG    . MET C 1 128 ? 98.651  163.516 143.410 1.00 43.55  ? 99  MET C CG    1 
ATOM   5079  S SD    . MET C 1 128 ? 100.317 163.835 144.008 1.00 43.55  ? 99  MET C SD    1 
ATOM   5080  C CE    . MET C 1 128 ? 100.339 162.861 145.503 1.00 43.55  ? 99  MET C CE    1 
ATOM   5081  N N     . VAL C 1 129 ? 96.603  160.602 144.524 1.00 45.93  ? 100 VAL C N     1 
ATOM   5082  C CA    . VAL C 1 129 ? 95.899  160.255 145.749 1.00 45.93  ? 100 VAL C CA    1 
ATOM   5083  C C     . VAL C 1 129 ? 96.914  160.267 146.884 1.00 45.93  ? 100 VAL C C     1 
ATOM   5084  O O     . VAL C 1 129 ? 98.118  160.114 146.671 1.00 45.93  ? 100 VAL C O     1 
ATOM   5085  C CB    . VAL C 1 129 ? 95.198  158.878 145.641 1.00 45.93  ? 100 VAL C CB    1 
ATOM   5086  C CG1   . VAL C 1 129 ? 94.176  158.677 146.772 1.00 45.93  ? 100 VAL C CG1   1 
ATOM   5087  C CG2   . VAL C 1 129 ? 94.541  158.725 144.264 1.00 45.93  ? 100 VAL C CG2   1 
ATOM   5088  N N     . GLY C 1 130 ? 96.416  160.491 148.101 1.00 49.86  ? 101 GLY C N     1 
ATOM   5089  C CA    . GLY C 1 130 ? 97.291  160.480 149.260 1.00 49.86  ? 101 GLY C CA    1 
ATOM   5090  C C     . GLY C 1 130 ? 97.942  159.131 149.497 1.00 49.86  ? 101 GLY C C     1 
ATOM   5091  O O     . GLY C 1 130 ? 99.101  159.063 149.913 1.00 49.86  ? 101 GLY C O     1 
ATOM   5092  N N     . SER C 1 131 ? 97.219  158.043 149.217 1.00 53.22  ? 102 SER C N     1 
ATOM   5093  C CA    . SER C 1 131 ? 97.788  156.708 149.379 1.00 53.22  ? 102 SER C CA    1 
ATOM   5094  C C     . SER C 1 131 ? 98.971  156.478 148.445 1.00 53.22  ? 102 SER C C     1 
ATOM   5095  O O     . SER C 1 131 ? 99.870  155.694 148.767 1.00 53.22  ? 102 SER C O     1 
ATOM   5096  C CB    . SER C 1 131 ? 96.712  155.652 149.138 1.00 53.22  ? 102 SER C CB    1 
ATOM   5097  O OG    . SER C 1 131 ? 95.504  156.000 149.790 1.00 53.22  ? 102 SER C OG    1 
ATOM   5098  N N     . GLU C 1 132 ? 98.994  157.149 147.291 1.00 53.96  ? 103 GLU C N     1 
ATOM   5099  C CA    . GLU C 1 132 ? 100.140 157.052 146.397 1.00 53.96  ? 103 GLU C CA    1 
ATOM   5100  C C     . GLU C 1 132 ? 101.398 157.677 146.992 1.00 53.96  ? 103 GLU C C     1 
ATOM   5101  O O     . GLU C 1 132 ? 102.502 157.317 146.571 1.00 53.96  ? 103 GLU C O     1 
ATOM   5102  C CB    . GLU C 1 132 ? 99.806  157.712 145.054 1.00 53.96  ? 103 GLU C CB    1 
ATOM   5103  C CG    . GLU C 1 132 ? 100.947 157.737 144.036 1.00 53.96  ? 103 GLU C CG    1 
ATOM   5104  C CD    . GLU C 1 132 ? 100.479 158.038 142.622 1.00 53.96  ? 103 GLU C CD    1 
ATOM   5105  O OE1   . GLU C 1 132 ? 99.300  158.406 142.439 1.00 53.96  ? 103 GLU C OE1   1 
ATOM   5106  O OE2   . GLU C 1 132 ? 101.298 157.908 141.689 1.00 53.96  ? 103 GLU C OE2   1 
ATOM   5107  N N     . VAL C 1 133 ? 101.267 158.598 147.953 1.00 55.39  ? 104 VAL C N     1 
ATOM   5108  C CA    . VAL C 1 133 ? 102.454 159.257 148.495 1.00 55.39  ? 104 VAL C CA    1 
ATOM   5109  C C     . VAL C 1 133 ? 103.287 158.268 149.303 1.00 55.39  ? 104 VAL C C     1 
ATOM   5110  O O     . VAL C 1 133 ? 104.522 158.309 149.270 1.00 55.39  ? 104 VAL C O     1 
ATOM   5111  C CB    . VAL C 1 133 ? 102.042 160.496 149.317 1.00 55.39  ? 104 VAL C CB    1 
ATOM   5112  C CG1   . VAL C 1 133 ? 103.147 160.969 150.263 1.00 55.39  ? 104 VAL C CG1   1 
ATOM   5113  C CG2   . VAL C 1 133 ? 101.627 161.615 148.379 1.00 55.39  ? 104 VAL C CG2   1 
ATOM   5114  N N     . TYR C 1 134 ? 102.636 157.369 150.035 1.00 56.14  ? 105 TYR C N     1 
ATOM   5115  C CA    . TYR C 1 134 ? 103.362 156.319 150.737 1.00 56.14  ? 105 TYR C CA    1 
ATOM   5116  C C     . TYR C 1 134 ? 103.878 155.295 149.735 1.00 56.14  ? 105 TYR C C     1 
ATOM   5117  O O     . TYR C 1 134 ? 103.135 154.835 148.864 1.00 56.14  ? 105 TYR C O     1 
ATOM   5118  C CB    . TYR C 1 134 ? 102.463 155.649 151.775 1.00 56.14  ? 105 TYR C CB    1 
ATOM   5119  C CG    . TYR C 1 134 ? 101.845 156.620 152.754 1.00 56.14  ? 105 TYR C CG    1 
ATOM   5120  C CD1   . TYR C 1 134 ? 102.638 157.411 153.572 1.00 56.14  ? 105 TYR C CD1   1 
ATOM   5121  C CD2   . TYR C 1 134 ? 100.468 156.751 152.854 1.00 56.14  ? 105 TYR C CD2   1 
ATOM   5122  C CE1   . TYR C 1 134 ? 102.079 158.302 154.462 1.00 56.14  ? 105 TYR C CE1   1 
ATOM   5123  C CE2   . TYR C 1 134 ? 99.901  157.639 153.743 1.00 56.14  ? 105 TYR C CE2   1 
ATOM   5124  C CZ    . TYR C 1 134 ? 100.712 158.412 154.543 1.00 56.14  ? 105 TYR C CZ    1 
ATOM   5125  O OH    . TYR C 1 134 ? 100.152 159.298 155.430 1.00 56.14  ? 105 TYR C OH    1 
ATOM   5126  N N     . SER C 1 135 ? 105.157 154.948 149.853 1.00 64.98  ? 106 SER C N     1 
ATOM   5127  C CA    . SER C 1 135 ? 105.785 154.025 148.920 1.00 64.98  ? 106 SER C CA    1 
ATOM   5128  C C     . SER C 1 135 ? 106.985 153.376 149.590 1.00 64.98  ? 106 SER C C     1 
ATOM   5129  O O     . SER C 1 135 ? 107.658 153.992 150.421 1.00 64.98  ? 106 SER C O     1 
ATOM   5130  C CB    . SER C 1 135 ? 106.215 154.736 147.634 1.00 64.98  ? 106 SER C CB    1 
ATOM   5131  O OG    . SER C 1 135 ? 106.985 153.876 146.814 1.00 64.98  ? 106 SER C OG    1 
ATOM   5132  N N     . SER C 1 136 ? 107.240 152.122 149.214 1.00 70.99  ? 107 SER C N     1 
ATOM   5133  C CA    . SER C 1 136 ? 108.324 151.349 149.806 1.00 70.99  ? 107 SER C CA    1 
ATOM   5134  C C     . SER C 1 136 ? 109.682 151.630 149.171 1.00 70.99  ? 107 SER C C     1 
ATOM   5135  O O     . SER C 1 136 ? 110.703 151.467 149.848 1.00 70.99  ? 107 SER C O     1 
ATOM   5136  C CB    . SER C 1 136 ? 108.013 149.856 149.692 1.00 70.99  ? 107 SER C CB    1 
ATOM   5137  O OG    . SER C 1 136 ? 107.583 149.527 148.383 1.00 70.99  ? 107 SER C OG    1 
ATOM   5138  N N     . GLU C 1 137 ? 109.716 152.059 147.906 1.00 74.93  ? 108 GLU C N     1 
ATOM   5139  C CA    . GLU C 1 137 ? 110.959 152.248 147.163 1.00 74.93  ? 108 GLU C CA    1 
ATOM   5140  C C     . GLU C 1 137 ? 111.466 153.681 147.169 1.00 74.93  ? 108 GLU C C     1 
ATOM   5141  O O     . GLU C 1 137 ? 112.681 153.886 147.074 1.00 74.93  ? 108 GLU C O     1 
ATOM   5142  C CB    . GLU C 1 137 ? 110.775 151.802 145.706 1.00 74.93  ? 108 GLU C CB    1 
ATOM   5143  C CG    . GLU C 1 137 ? 112.062 151.355 145.004 1.00 74.93  ? 108 GLU C CG    1 
ATOM   5144  C CD    . GLU C 1 137 ? 112.597 150.021 145.498 1.00 74.93  ? 108 GLU C CD    1 
ATOM   5145  O OE1   . GLU C 1 137 ? 111.918 149.365 146.313 1.00 74.93  ? 108 GLU C OE1   1 
ATOM   5146  O OE2   . GLU C 1 137 ? 113.703 149.629 145.071 1.00 74.93  ? 108 GLU C OE2   1 
ATOM   5147  N N     . VAL C 1 138 ? 110.573 154.668 147.277 1.00 70.24  ? 109 VAL C N     1 
ATOM   5148  C CA    . VAL C 1 138 ? 110.924 156.084 147.274 1.00 70.24  ? 109 VAL C CA    1 
ATOM   5149  C C     . VAL C 1 138 ? 110.354 156.731 148.527 1.00 70.24  ? 109 VAL C C     1 
ATOM   5150  O O     . VAL C 1 138 ? 109.322 156.309 149.057 1.00 70.24  ? 109 VAL C O     1 
ATOM   5151  C CB    . VAL C 1 138 ? 110.418 156.803 145.998 1.00 70.24  ? 109 VAL C CB    1 
ATOM   5152  C CG1   . VAL C 1 138 ? 110.796 156.009 144.757 1.00 70.24  ? 109 VAL C CG1   1 
ATOM   5153  C CG2   . VAL C 1 138 ? 108.906 157.020 146.037 1.00 70.24  ? 109 VAL C CG2   1 
ATOM   5154  N N     . LYS C 1 139 ? 111.047 157.760 149.003 1.00 66.59  ? 110 LYS C N     1 
ATOM   5155  C CA    . LYS C 1 139 ? 110.579 158.514 150.153 1.00 66.59  ? 110 LYS C CA    1 
ATOM   5156  C C     . LYS C 1 139 ? 109.298 159.260 149.794 1.00 66.59  ? 110 LYS C C     1 
ATOM   5157  O O     . LYS C 1 139 ? 109.085 159.649 148.642 1.00 66.59  ? 110 LYS C O     1 
ATOM   5158  C CB    . LYS C 1 139 ? 111.670 159.481 150.615 1.00 66.59  ? 110 LYS C CB    1 
ATOM   5159  C CG    . LYS C 1 139 ? 111.504 160.036 152.028 1.00 66.59  ? 110 LYS C CG    1 
ATOM   5160  C CD    . LYS C 1 139 ? 112.288 161.336 152.251 1.00 66.59  ? 110 LYS C CD    1 
ATOM   5161  C CE    . LYS C 1 139 ? 113.808 161.156 152.162 1.00 66.59  ? 110 LYS C CE    1 
ATOM   5162  N NZ    . LYS C 1 139 ? 114.520 162.460 152.261 1.00 66.59  ? 110 LYS C NZ    1 
ATOM   5163  N N     . LYS C 1 140 ? 108.425 159.423 150.795 1.00 61.40  ? 111 LYS C N     1 
ATOM   5164  C CA    . LYS C 1 140 ? 107.136 160.083 150.578 1.00 61.40  ? 111 LYS C CA    1 
ATOM   5165  C C     . LYS C 1 140 ? 107.317 161.521 150.104 1.00 61.40  ? 111 LYS C C     1 
ATOM   5166  O O     . LYS C 1 140 ? 106.620 161.983 149.188 1.00 61.40  ? 111 LYS C O     1 
ATOM   5167  C CB    . LYS C 1 140 ? 106.290 160.044 151.857 1.00 61.40  ? 111 LYS C CB    1 
ATOM   5168  C CG    . LYS C 1 140 ? 106.940 160.554 153.146 1.00 61.40  ? 111 LYS C CG    1 
ATOM   5169  C CD    . LYS C 1 140 ? 105.995 160.375 154.326 1.00 61.40  ? 111 LYS C CD    1 
ATOM   5170  C CE    . LYS C 1 140 ? 106.695 160.619 155.650 1.00 61.40  ? 111 LYS C CE    1 
ATOM   5171  N NZ    . LYS C 1 140 ? 107.527 159.454 156.062 1.00 61.40  ? 111 LYS C NZ    1 
ATOM   5172  N N     . THR C 1 141 ? 108.269 162.233 150.704 1.00 63.11  ? 112 THR C N     1 
ATOM   5173  C CA    . THR C 1 141 ? 108.565 163.598 150.290 1.00 63.11  ? 112 THR C CA    1 
ATOM   5174  C C     . THR C 1 141 ? 109.075 163.650 148.850 1.00 63.11  ? 112 THR C C     1 
ATOM   5175  O O     . THR C 1 141 ? 108.772 164.594 148.106 1.00 63.11  ? 112 THR C O     1 
ATOM   5176  C CB    . THR C 1 141 ? 109.589 164.190 151.258 1.00 63.11  ? 112 THR C CB    1 
ATOM   5177  O OG1   . THR C 1 141 ? 109.021 164.266 152.572 1.00 63.11  ? 112 THR C OG1   1 
ATOM   5178  C CG2   . THR C 1 141 ? 110.015 165.548 150.825 1.00 63.11  ? 112 THR C CG2   1 
ATOM   5179  N N     . GLU C 1 142 ? 109.851 162.643 148.443 1.00 64.87  ? 113 GLU C N     1 
ATOM   5180  C CA    . GLU C 1 142 ? 110.420 162.641 147.099 1.00 64.87  ? 113 GLU C CA    1 
ATOM   5181  C C     . GLU C 1 142 ? 109.325 162.491 146.047 1.00 64.87  ? 113 GLU C C     1 
ATOM   5182  O O     . GLU C 1 142 ? 109.316 163.215 145.046 1.00 64.87  ? 113 GLU C O     1 
ATOM   5183  C CB    . GLU C 1 142 ? 111.465 161.521 146.977 1.00 64.87  ? 113 GLU C CB    1 
ATOM   5184  C CG    . GLU C 1 142 ? 111.884 161.046 145.553 1.00 64.87  ? 113 GLU C CG    1 
ATOM   5185  C CD    . GLU C 1 142 ? 112.196 162.154 144.537 1.00 64.87  ? 113 GLU C CD    1 
ATOM   5186  O OE1   . GLU C 1 142 ? 112.350 161.825 143.342 1.00 64.87  ? 113 GLU C OE1   1 
ATOM   5187  O OE2   . GLU C 1 142 ? 112.331 163.334 144.920 1.00 64.87  ? 113 GLU C OE2   1 
ATOM   5188  N N     . VAL C 1 143 ? 108.392 161.557 146.255 1.00 61.00  ? 114 VAL C N     1 
ATOM   5189  C CA    . VAL C 1 143 ? 107.284 161.416 145.310 1.00 61.00  ? 114 VAL C CA    1 
ATOM   5190  C C     . VAL C 1 143 ? 106.372 162.637 145.360 1.00 61.00  ? 114 VAL C C     1 
ATOM   5191  O O     . VAL C 1 143 ? 105.757 162.998 144.344 1.00 61.00  ? 114 VAL C O     1 
ATOM   5192  C CB    . VAL C 1 143 ? 106.493 160.108 145.547 1.00 61.00  ? 114 VAL C CB    1 
ATOM   5193  C CG1   . VAL C 1 143 ? 105.901 160.018 146.959 1.00 61.00  ? 114 VAL C CG1   1 
ATOM   5194  C CG2   . VAL C 1 143 ? 105.388 159.949 144.501 1.00 61.00  ? 114 VAL C CG2   1 
ATOM   5195  N N     . LEU C 1 144 ? 106.256 163.281 146.530 1.00 56.78  ? 115 LEU C N     1 
ATOM   5196  C CA    . LEU C 1 144 ? 105.479 164.516 146.613 1.00 56.78  ? 115 LEU C CA    1 
ATOM   5197  C C     . LEU C 1 144 ? 106.057 165.598 145.710 1.00 56.78  ? 115 LEU C C     1 
ATOM   5198  O O     . LEU C 1 144 ? 105.337 166.174 144.890 1.00 56.78  ? 115 LEU C O     1 
ATOM   5199  C CB    . LEU C 1 144 ? 105.410 165.014 148.055 1.00 56.78  ? 115 LEU C CB    1 
ATOM   5200  C CG    . LEU C 1 144 ? 104.207 164.492 148.840 1.00 56.78  ? 115 LEU C CG    1 
ATOM   5201  C CD1   . LEU C 1 144 ? 104.450 164.565 150.329 1.00 56.78  ? 115 LEU C CD1   1 
ATOM   5202  C CD2   . LEU C 1 144 ? 102.944 165.271 148.483 1.00 56.78  ? 115 LEU C CD2   1 
ATOM   5203  N N     . MET C 1 145 ? 107.361 165.870 145.825 1.00 60.18  ? 116 MET C N     1 
ATOM   5204  C CA    . MET C 1 145 ? 107.972 166.831 144.904 1.00 60.18  ? 116 MET C CA    1 
ATOM   5205  C C     . MET C 1 145 ? 107.985 166.343 143.464 1.00 60.18  ? 116 MET C C     1 
ATOM   5206  O O     . MET C 1 145 ? 107.963 167.170 142.547 1.00 60.18  ? 116 MET C O     1 
ATOM   5207  C CB    . MET C 1 145 ? 109.394 167.204 145.325 1.00 60.18  ? 116 MET C CB    1 
ATOM   5208  C CG    . MET C 1 145 ? 109.712 168.704 145.174 1.00 60.18  ? 116 MET C CG    1 
ATOM   5209  S SD    . MET C 1 145 ? 108.768 169.892 146.151 1.00 60.18  ? 116 MET C SD    1 
ATOM   5210  C CE    . MET C 1 145 ? 109.971 171.206 146.333 1.00 60.18  ? 116 MET C CE    1 
ATOM   5211  N N     . GLU C 1 146 ? 108.020 165.028 143.240 1.00 61.75  ? 117 GLU C N     1 
ATOM   5212  C CA    . GLU C 1 146 ? 107.952 164.507 141.878 1.00 61.75  ? 117 GLU C CA    1 
ATOM   5213  C C     . GLU C 1 146 ? 106.640 164.897 141.212 1.00 61.75  ? 117 GLU C C     1 
ATOM   5214  O O     . GLU C 1 146 ? 106.632 165.488 140.125 1.00 61.75  ? 117 GLU C O     1 
ATOM   5215  C CB    . GLU C 1 146 ? 108.113 162.988 141.897 1.00 61.75  ? 117 GLU C CB    1 
ATOM   5216  C CG    . GLU C 1 146 ? 108.086 162.345 140.527 1.00 61.75  ? 117 GLU C CG    1 
ATOM   5217  C CD    . GLU C 1 146 ? 108.935 161.092 140.459 1.00 61.75  ? 117 GLU C CD    1 
ATOM   5218  O OE1   . GLU C 1 146 ? 108.556 160.081 141.086 1.00 61.75  ? 117 GLU C OE1   1 
ATOM   5219  O OE2   . GLU C 1 146 ? 109.983 161.117 139.780 1.00 61.75  ? 117 GLU C OE2   1 
ATOM   5220  N N     . ASN C 1 147 ? 105.520 164.620 141.879 1.00 53.73  ? 118 ASN C N     1 
ATOM   5221  C CA    . ASN C 1 147 ? 104.229 165.023 141.329 1.00 53.73  ? 118 ASN C CA    1 
ATOM   5222  C C     . ASN C 1 147 ? 104.066 166.539 141.323 1.00 53.73  ? 118 ASN C C     1 
ATOM   5223  O O     . ASN C 1 147 ? 103.418 167.083 140.422 1.00 53.73  ? 118 ASN C O     1 
ATOM   5224  C CB    . ASN C 1 147 ? 103.094 164.373 142.115 1.00 53.73  ? 118 ASN C CB    1 
ATOM   5225  C CG    . ASN C 1 147 ? 102.778 162.974 141.629 1.00 53.73  ? 118 ASN C CG    1 
ATOM   5226  O OD1   . ASN C 1 147 ? 102.161 162.796 140.580 1.00 53.73  ? 118 ASN C OD1   1 
ATOM   5227  N ND2   . ASN C 1 147 ? 103.199 161.971 142.392 1.00 53.73  ? 118 ASN C ND2   1 
ATOM   5228  N N     . PHE C 1 148 ? 104.643 167.231 142.309 1.00 52.33  ? 119 PHE C N     1 
ATOM   5229  C CA    . PHE C 1 148 ? 104.518 168.683 142.396 1.00 52.33  ? 119 PHE C CA    1 
ATOM   5230  C C     . PHE C 1 148 ? 105.191 169.363 141.211 1.00 52.33  ? 119 PHE C C     1 
ATOM   5231  O O     . PHE C 1 148 ? 104.613 170.254 140.579 1.00 52.33  ? 119 PHE C O     1 
ATOM   5232  C CB    . PHE C 1 148 ? 105.133 169.152 143.716 1.00 52.33  ? 119 PHE C CB    1 
ATOM   5233  C CG    . PHE C 1 148 ? 104.807 170.564 144.092 1.00 52.33  ? 119 PHE C CG    1 
ATOM   5234  C CD1   . PHE C 1 148 ? 103.711 170.838 144.888 1.00 52.33  ? 119 PHE C CD1   1 
ATOM   5235  C CD2   . PHE C 1 148 ? 105.619 171.610 143.693 1.00 52.33  ? 119 PHE C CD2   1 
ATOM   5236  C CE1   . PHE C 1 148 ? 103.414 172.129 145.256 1.00 52.33  ? 119 PHE C CE1   1 
ATOM   5237  C CE2   . PHE C 1 148 ? 105.324 172.905 144.059 1.00 52.33  ? 119 PHE C CE2   1 
ATOM   5238  C CZ    . PHE C 1 148 ? 104.224 173.162 144.847 1.00 52.33  ? 119 PHE C CZ    1 
ATOM   5239  N N     . ARG C 1 149 ? 106.417 168.948 140.892 1.00 61.41  ? 120 ARG C N     1 
ATOM   5240  C CA    . ARG C 1 149 ? 107.144 169.503 139.761 1.00 61.41  ? 120 ARG C CA    1 
ATOM   5241  C C     . ARG C 1 149 ? 106.663 168.958 138.424 1.00 61.41  ? 120 ARG C C     1 
ATOM   5242  O O     . ARG C 1 149 ? 106.884 169.606 137.397 1.00 61.41  ? 120 ARG C O     1 
ATOM   5243  C CB    . ARG C 1 149 ? 108.638 169.227 139.921 1.00 61.41  ? 120 ARG C CB    1 
ATOM   5244  C CG    . ARG C 1 149 ? 109.299 170.054 141.012 1.00 61.41  ? 120 ARG C CG    1 
ATOM   5245  C CD    . ARG C 1 149 ? 110.792 169.790 141.084 1.00 61.41  ? 120 ARG C CD    1 
ATOM   5246  N NE    . ARG C 1 149 ? 111.077 168.499 141.708 1.00 61.41  ? 120 ARG C NE    1 
ATOM   5247  C CZ    . ARG C 1 149 ? 112.168 167.761 141.521 1.00 61.41  ? 120 ARG C CZ    1 
ATOM   5248  N NH1   . ARG C 1 149 ? 113.140 168.135 140.701 1.00 61.41  ? 120 ARG C NH1   1 
ATOM   5249  N NH2   . ARG C 1 149 ? 112.288 166.610 142.175 1.00 61.41  ? 120 ARG C NH2   1 
ATOM   5250  N N     . ARG C 1 150 ? 106.015 167.789 138.407 1.00 56.15  ? 121 ARG C N     1 
ATOM   5251  C CA    . ARG C 1 150 ? 105.490 167.255 137.155 1.00 56.15  ? 121 ARG C CA    1 
ATOM   5252  C C     . ARG C 1 150 ? 104.390 168.128 136.562 1.00 56.15  ? 121 ARG C C     1 
ATOM   5253  O O     . ARG C 1 150 ? 104.170 168.079 135.347 1.00 56.15  ? 121 ARG C O     1 
ATOM   5254  C CB    . ARG C 1 150 ? 104.971 165.834 137.380 1.00 56.15  ? 121 ARG C CB    1 
ATOM   5255  C CG    . ARG C 1 150 ? 104.554 165.100 136.116 1.00 56.15  ? 121 ARG C CG    1 
ATOM   5256  C CD    . ARG C 1 150 ? 104.325 163.626 136.407 1.00 56.15  ? 121 ARG C CD    1 
ATOM   5257  N NE    . ARG C 1 150 ? 105.593 162.908 136.533 1.00 56.15  ? 121 ARG C NE    1 
ATOM   5258  C CZ    . ARG C 1 150 ? 105.817 161.828 137.278 1.00 56.15  ? 121 ARG C CZ    1 
ATOM   5259  N NH1   . ARG C 1 150 ? 104.857 161.241 137.980 1.00 56.15  ? 121 ARG C NH1   1 
ATOM   5260  N NH2   . ARG C 1 150 ? 107.042 161.314 137.313 1.00 56.15  ? 121 ARG C NH2   1 
ATOM   5261  N N     . ALA C 1 151 ? 103.695 168.918 137.383 1.00 48.01  ? 122 ALA C N     1 
ATOM   5262  C CA    . ALA C 1 151 ? 102.631 169.796 136.917 1.00 48.01  ? 122 ALA C CA    1 
ATOM   5263  C C     . ALA C 1 151 ? 103.117 171.153 136.416 1.00 48.01  ? 122 ALA C C     1 
ATOM   5264  O O     . ALA C 1 151 ? 102.308 171.909 135.874 1.00 48.01  ? 122 ALA C O     1 
ATOM   5265  C CB    . ALA C 1 151 ? 101.614 170.019 138.041 1.00 48.01  ? 122 ALA C CB    1 
ATOM   5266  N N     . ILE C 1 152 ? 104.395 171.492 136.577 1.00 56.49  ? 123 ILE C N     1 
ATOM   5267  C CA    . ILE C 1 152 ? 104.919 172.792 136.159 1.00 56.49  ? 123 ILE C CA    1 
ATOM   5268  C C     . ILE C 1 152 ? 105.352 172.647 134.704 1.00 56.49  ? 123 ILE C C     1 
ATOM   5269  O O     . ILE C 1 152 ? 106.441 172.144 134.423 1.00 56.49  ? 123 ILE C O     1 
ATOM   5270  C CB    . ILE C 1 152 ? 106.081 173.255 137.042 1.00 56.49  ? 123 ILE C CB    1 
ATOM   5271  C CG1   . ILE C 1 152 ? 105.646 173.456 138.504 1.00 56.49  ? 123 ILE C CG1   1 
ATOM   5272  C CG2   . ILE C 1 152 ? 106.687 174.540 136.476 1.00 56.49  ? 123 ILE C CG2   1 
ATOM   5273  C CD1   . ILE C 1 152 ? 106.802 173.471 139.498 1.00 56.49  ? 123 ILE C CD1   1 
ATOM   5274  N N     . GLY C 1 153 ? 104.510 173.095 133.771 1.00 58.75  ? 124 GLY C N     1 
ATOM   5275  C CA    . GLY C 1 153 ? 104.840 173.005 132.364 1.00 58.75  ? 124 GLY C CA    1 
ATOM   5276  C C     . GLY C 1 153 ? 105.676 174.192 131.924 1.00 58.75  ? 124 GLY C C     1 
ATOM   5277  O O     . GLY C 1 153 ? 105.592 175.272 132.497 1.00 58.75  ? 124 GLY C O     1 
ATOM   5278  N N     . LEU C 1 154 ? 106.488 173.976 130.891 1.00 66.98  ? 125 LEU C N     1 
ATOM   5279  C CA    . LEU C 1 154 ? 107.270 175.030 130.266 1.00 66.98  ? 125 LEU C CA    1 
ATOM   5280  C C     . LEU C 1 154 ? 107.245 174.804 128.765 1.00 66.98  ? 125 LEU C C     1 
ATOM   5281  O O     . LEU C 1 154 ? 107.083 173.673 128.302 1.00 66.98  ? 125 LEU C O     1 
ATOM   5282  C CB    . LEU C 1 154 ? 108.720 175.044 130.767 1.00 66.98  ? 125 LEU C CB    1 
ATOM   5283  C CG    . LEU C 1 154 ? 108.920 175.299 132.262 1.00 66.98  ? 125 LEU C CG    1 
ATOM   5284  C CD1   . LEU C 1 154 ? 109.141 173.988 133.001 1.00 66.98  ? 125 LEU C CD1   1 
ATOM   5285  C CD2   . LEU C 1 154 ? 110.083 176.247 132.495 1.00 66.98  ? 125 LEU C CD2   1 
ATOM   5286  N N     . ARG C 1 155 ? 107.377 175.896 128.016 1.00 76.34  ? 126 ARG C N     1 
ATOM   5287  C CA    . ARG C 1 155 ? 107.479 175.866 126.564 1.00 76.34  ? 126 ARG C CA    1 
ATOM   5288  C C     . ARG C 1 155 ? 108.693 176.683 126.149 1.00 76.34  ? 126 ARG C C     1 
ATOM   5289  O O     . ARG C 1 155 ? 108.854 177.829 126.583 1.00 76.34  ? 126 ARG C O     1 
ATOM   5290  C CB    . ARG C 1 155 ? 106.199 176.393 125.900 1.00 76.34  ? 126 ARG C CB    1 
ATOM   5291  C CG    . ARG C 1 155 ? 105.877 177.854 126.168 1.00 76.34  ? 126 ARG C CG    1 
ATOM   5292  C CD    . ARG C 1 155 ? 104.446 178.187 125.766 1.00 76.34  ? 126 ARG C CD    1 
ATOM   5293  N NE    . ARG C 1 155 ? 104.161 177.854 124.373 1.00 76.34  ? 126 ARG C NE    1 
ATOM   5294  C CZ    . ARG C 1 155 ? 103.056 178.182 123.712 1.00 76.34  ? 126 ARG C CZ    1 
ATOM   5295  N NH1   . ARG C 1 155 ? 102.073 178.869 124.280 1.00 76.34  ? 126 ARG C NH1   1 
ATOM   5296  N NH2   . ARG C 1 155 ? 102.929 177.810 122.442 1.00 76.34  ? 126 ARG C NH2   1 
ATOM   5297  N N     . ILE C 1 156 ? 109.541 176.079 125.318 1.00 80.33  ? 127 ILE C N     1 
ATOM   5298  C CA    . ILE C 1 156 ? 110.802 176.657 124.867 1.00 80.33  ? 127 ILE C CA    1 
ATOM   5299  C C     . ILE C 1 156 ? 110.680 176.897 123.371 1.00 80.33  ? 127 ILE C C     1 
ATOM   5300  O O     . ILE C 1 156 ? 110.293 175.992 122.619 1.00 80.33  ? 127 ILE C O     1 
ATOM   5301  C CB    . ILE C 1 156 ? 111.990 175.733 125.196 1.00 80.33  ? 127 ILE C CB    1 
ATOM   5302  C CG1   . ILE C 1 156 ? 112.248 175.705 126.709 1.00 80.33  ? 127 ILE C CG1   1 
ATOM   5303  C CG2   . ILE C 1 156 ? 113.262 176.166 124.452 1.00 80.33  ? 127 ILE C CG2   1 
ATOM   5304  C CD1   . ILE C 1 156 ? 112.699 174.354 127.218 1.00 80.33  ? 127 ILE C CD1   1 
ATOM   5305  N N     . LYS C 1 157 ? 111.003 178.116 122.946 1.00 80.98  ? 128 LYS C N     1 
ATOM   5306  C CA    . LYS C 1 157 ? 110.887 178.515 121.549 1.00 80.98  ? 128 LYS C CA    1 
ATOM   5307  C C     . LYS C 1 157 ? 112.133 178.109 120.766 1.00 80.98  ? 128 LYS C C     1 
ATOM   5308  O O     . LYS C 1 157 ? 113.229 178.022 121.319 1.00 80.98  ? 128 LYS C O     1 
ATOM   5309  C CB    . LYS C 1 157 ? 110.672 180.030 121.437 1.00 80.98  ? 128 LYS C CB    1 
ATOM   5310  C CG    . LYS C 1 157 ? 109.590 180.612 122.352 1.00 80.98  ? 128 LYS C CG    1 
ATOM   5311  C CD    . LYS C 1 157 ? 108.247 179.917 122.183 1.00 80.98  ? 128 LYS C CD    1 
ATOM   5312  C CE    . LYS C 1 157 ? 107.078 180.804 122.594 1.00 80.98  ? 128 LYS C CE    1 
ATOM   5313  N NZ    . LYS C 1 157 ? 107.051 181.041 124.064 1.00 80.98  ? 128 LYS C NZ    1 
ATOM   5314  N N     . VAL C 1 267 ? 108.578 175.094 118.584 1.00 82.09  ? 238 VAL C N     1 
ATOM   5315  C CA    . VAL C 1 267 ? 108.309 175.372 119.989 1.00 82.09  ? 238 VAL C CA    1 
ATOM   5316  C C     . VAL C 1 267 ? 107.945 174.067 120.684 1.00 82.09  ? 238 VAL C C     1 
ATOM   5317  O O     . VAL C 1 267 ? 106.930 173.453 120.350 1.00 82.09  ? 238 VAL C O     1 
ATOM   5318  C CB    . VAL C 1 267 ? 107.187 176.424 120.160 1.00 82.09  ? 238 VAL C CB    1 
ATOM   5319  C CG1   . VAL C 1 267 ? 107.004 176.777 121.642 1.00 82.09  ? 238 VAL C CG1   1 
ATOM   5320  C CG2   . VAL C 1 267 ? 107.478 177.678 119.318 1.00 82.09  ? 238 VAL C CG2   1 
ATOM   5321  N N     . GLN C 1 268 ? 108.765 173.665 121.657 1.00 78.86  ? 239 GLN C N     1 
ATOM   5322  C CA    . GLN C 1 268 ? 108.647 172.372 122.324 1.00 78.86  ? 239 GLN C CA    1 
ATOM   5323  C C     . GLN C 1 268 ? 108.219 172.576 123.771 1.00 78.86  ? 239 GLN C C     1 
ATOM   5324  O O     . GLN C 1 268 ? 108.748 173.449 124.465 1.00 78.86  ? 239 GLN C O     1 
ATOM   5325  C CB    . GLN C 1 268 ? 109.976 171.608 122.263 1.00 78.86  ? 239 GLN C CB    1 
ATOM   5326  C CG    . GLN C 1 268 ? 110.107 170.449 123.249 1.00 78.86  ? 239 GLN C CG    1 
ATOM   5327  C CD    . GLN C 1 268 ? 111.138 169.430 122.809 1.00 78.86  ? 239 GLN C CD    1 
ATOM   5328  O OE1   . GLN C 1 268 ? 110.844 168.240 122.697 1.00 78.86  ? 239 GLN C OE1   1 
ATOM   5329  N NE2   . GLN C 1 268 ? 112.357 169.893 122.553 1.00 78.86  ? 239 GLN C NE2   1 
ATOM   5330  N N     . ASP C 1 269 ? 107.275 171.748 124.219 1.00 72.17  ? 240 ASP C N     1 
ATOM   5331  C CA    . ASP C 1 269 ? 106.683 171.830 125.550 1.00 72.17  ? 240 ASP C CA    1 
ATOM   5332  C C     . ASP C 1 269 ? 107.123 170.632 126.382 1.00 72.17  ? 240 ASP C C     1 
ATOM   5333  O O     . ASP C 1 269 ? 107.110 169.497 125.896 1.00 72.17  ? 240 ASP C O     1 
ATOM   5334  C CB    . ASP C 1 269 ? 105.158 171.883 125.455 1.00 72.17  ? 240 ASP C CB    1 
ATOM   5335  C CG    . ASP C 1 269 ? 104.673 173.010 124.564 1.00 72.17  ? 240 ASP C CG    1 
ATOM   5336  O OD1   . ASP C 1 269 ? 105.484 173.904 124.247 1.00 72.17  ? 240 ASP C OD1   1 
ATOM   5337  O OD2   . ASP C 1 269 ? 103.485 173.005 124.178 1.00 72.17  ? 240 ASP C OD2   1 
ATOM   5338  N N     . VAL C 1 270 ? 107.510 170.890 127.632 1.00 66.84  ? 241 VAL C N     1 
ATOM   5339  C CA    . VAL C 1 270 ? 108.030 169.856 128.520 1.00 66.84  ? 241 VAL C CA    1 
ATOM   5340  C C     . VAL C 1 270 ? 107.768 170.273 129.961 1.00 66.84  ? 241 VAL C C     1 
ATOM   5341  O O     . VAL C 1 270 ? 107.747 171.462 130.287 1.00 66.84  ? 241 VAL C O     1 
ATOM   5342  C CB    . VAL C 1 270 ? 109.539 169.607 128.269 1.00 66.84  ? 241 VAL C CB    1 
ATOM   5343  C CG1   . VAL C 1 270 ? 110.384 170.785 128.759 1.00 66.84  ? 241 VAL C CG1   1 
ATOM   5344  C CG2   . VAL C 1 270 ? 109.992 168.308 128.921 1.00 66.84  ? 241 VAL C CG2   1 
ATOM   5345  N N     . THR C 1 271 ? 107.572 169.282 130.827 1.00 64.80  ? 242 THR C N     1 
ATOM   5346  C CA    . THR C 1 271 ? 107.326 169.523 132.242 1.00 64.80  ? 242 THR C CA    1 
ATOM   5347  C C     . THR C 1 271 ? 108.645 169.634 132.997 1.00 64.80  ? 242 THR C C     1 
ATOM   5348  O O     . THR C 1 271 ? 109.670 169.091 132.579 1.00 64.80  ? 242 THR C O     1 
ATOM   5349  C CB    . THR C 1 271 ? 106.476 168.408 132.852 1.00 64.80  ? 242 THR C CB    1 
ATOM   5350  O OG1   . THR C 1 271 ? 107.290 167.253 133.081 1.00 64.80  ? 242 THR C OG1   1 
ATOM   5351  C CG2   . THR C 1 271 ? 105.313 168.045 131.933 1.00 64.80  ? 242 THR C CG2   1 
ATOM   5352  N N     . LEU C 1 272 ? 108.604 170.347 134.125 1.00 63.16  ? 243 LEU C N     1 
ATOM   5353  C CA    . LEU C 1 272 ? 109.825 170.623 134.875 1.00 63.16  ? 243 LEU C CA    1 
ATOM   5354  C C     . LEU C 1 272 ? 110.420 169.363 135.492 1.00 63.16  ? 243 LEU C C     1 
ATOM   5355  O O     . LEU C 1 272 ? 111.636 169.300 135.703 1.00 63.16  ? 243 LEU C O     1 
ATOM   5356  C CB    . LEU C 1 272 ? 109.548 171.657 135.965 1.00 63.16  ? 243 LEU C CB    1 
ATOM   5357  C CG    . LEU C 1 272 ? 110.774 172.296 136.624 1.00 63.16  ? 243 LEU C CG    1 
ATOM   5358  C CD1   . LEU C 1 272 ? 110.575 173.794 136.769 1.00 63.16  ? 243 LEU C CD1   1 
ATOM   5359  C CD2   . LEU C 1 272 ? 111.065 171.671 137.982 1.00 63.16  ? 243 LEU C CD2   1 
ATOM   5360  N N     . GLN C 1 273 ? 109.595 168.360 135.802 1.00 65.04  ? 244 GLN C N     1 
ATOM   5361  C CA    . GLN C 1 273 ? 110.132 167.146 136.407 1.00 65.04  ? 244 GLN C CA    1 
ATOM   5362  C C     . GLN C 1 273 ? 110.946 166.333 135.407 1.00 65.04  ? 244 GLN C C     1 
ATOM   5363  O O     . GLN C 1 273 ? 111.836 165.576 135.813 1.00 65.04  ? 244 GLN C O     1 
ATOM   5364  C CB    . GLN C 1 273 ? 108.998 166.299 136.989 1.00 65.04  ? 244 GLN C CB    1 
ATOM   5365  C CG    . GLN C 1 273 ? 109.459 165.172 137.932 1.00 65.04  ? 244 GLN C CG    1 
ATOM   5366  C CD    . GLN C 1 273 ? 109.785 163.855 137.234 1.00 65.04  ? 244 GLN C CD    1 
ATOM   5367  O OE1   . GLN C 1 273 ? 109.537 163.680 136.041 1.00 65.04  ? 244 GLN C OE1   1 
ATOM   5368  N NE2   . GLN C 1 273 ? 110.363 162.926 137.985 1.00 65.04  ? 244 GLN C NE2   1 
ATOM   5369  N N     . ASP C 1 274 ? 110.652 166.461 134.108 1.00 68.42  ? 245 ASP C N     1 
ATOM   5370  C CA    . ASP C 1 274 ? 111.454 165.774 133.100 1.00 68.42  ? 245 ASP C CA    1 
ATOM   5371  C C     . ASP C 1 274 ? 112.894 166.267 133.102 1.00 68.42  ? 245 ASP C C     1 
ATOM   5372  O O     . ASP C 1 274 ? 113.817 165.484 132.848 1.00 68.42  ? 245 ASP C O     1 
ATOM   5373  C CB    . ASP C 1 274 ? 110.842 165.968 131.714 1.00 68.42  ? 245 ASP C CB    1 
ATOM   5374  C CG    . ASP C 1 274 ? 109.489 165.302 131.575 1.00 68.42  ? 245 ASP C CG    1 
ATOM   5375  O OD1   . ASP C 1 274 ? 109.363 164.119 131.953 1.00 68.42  ? 245 ASP C OD1   1 
ATOM   5376  O OD2   . ASP C 1 274 ? 108.551 165.963 131.082 1.00 68.42  ? 245 ASP C OD2   1 
ATOM   5377  N N     . LEU C 1 275 ? 113.103 167.556 133.384 1.00 67.65  ? 246 LEU C N     1 
ATOM   5378  C CA    . LEU C 1 275 ? 114.459 168.091 133.463 1.00 67.65  ? 246 LEU C CA    1 
ATOM   5379  C C     . LEU C 1 275 ? 115.244 167.433 134.590 1.00 67.65  ? 246 LEU C C     1 
ATOM   5380  O O     . LEU C 1 275 ? 116.402 167.043 134.403 1.00 67.65  ? 246 LEU C O     1 
ATOM   5381  C CB    . LEU C 1 275 ? 114.420 169.608 133.658 1.00 67.65  ? 246 LEU C CB    1 
ATOM   5382  C CG    . LEU C 1 275 ? 114.363 170.483 132.401 1.00 67.65  ? 246 LEU C CG    1 
ATOM   5383  C CD1   . LEU C 1 275 ? 113.297 170.015 131.419 1.00 67.65  ? 246 LEU C CD1   1 
ATOM   5384  C CD2   . LEU C 1 275 ? 114.124 171.930 132.794 1.00 67.65  ? 246 LEU C CD2   1 
ATOM   5385  N N     . ASP C 1 276 ? 114.627 167.286 135.765 1.00 70.09  ? 247 ASP C N     1 
ATOM   5386  C CA    . ASP C 1 276 ? 115.301 166.601 136.864 1.00 70.09  ? 247 ASP C CA    1 
ATOM   5387  C C     . ASP C 1 276 ? 115.514 165.126 136.553 1.00 70.09  ? 247 ASP C C     1 
ATOM   5388  O O     . ASP C 1 276 ? 116.549 164.557 136.917 1.00 70.09  ? 247 ASP C O     1 
ATOM   5389  C CB    . ASP C 1 276 ? 114.506 166.744 138.157 1.00 70.09  ? 247 ASP C CB    1 
ATOM   5390  C CG    . ASP C 1 276 ? 114.811 165.633 139.146 1.00 70.09  ? 247 ASP C CG    1 
ATOM   5391  O OD1   . ASP C 1 276 ? 115.868 165.693 139.807 1.00 70.09  ? 247 ASP C OD1   1 
ATOM   5392  O OD2   . ASP C 1 276 ? 113.998 164.692 139.253 1.00 70.09  ? 247 ASP C OD2   1 
ATOM   5393  N N     . ALA C 1 277 ? 114.537 164.487 135.903 1.00 70.11  ? 248 ALA C N     1 
ATOM   5394  C CA    . ALA C 1 277 ? 114.670 163.072 135.567 1.00 70.11  ? 248 ALA C CA    1 
ATOM   5395  C C     . ALA C 1 277 ? 115.825 162.842 134.601 1.00 70.11  ? 248 ALA C C     1 
ATOM   5396  O O     . ALA C 1 277 ? 116.559 161.854 134.723 1.00 70.11  ? 248 ALA C O     1 
ATOM   5397  C CB    . ALA C 1 277 ? 113.363 162.551 134.972 1.00 70.11  ? 248 ALA C CB    1 
ATOM   5398  N N     . ALA C 1 278 ? 116.004 163.746 133.638 1.00 68.48  ? 249 ALA C N     1 
ATOM   5399  C CA    . ALA C 1 278 ? 117.120 163.621 132.707 1.00 68.48  ? 249 ALA C CA    1 
ATOM   5400  C C     . ALA C 1 278 ? 118.449 163.950 133.380 1.00 68.48  ? 249 ALA C C     1 
ATOM   5401  O O     . ALA C 1 278 ? 119.433 163.223 133.205 1.00 68.48  ? 249 ALA C O     1 
ATOM   5402  C CB    . ALA C 1 278 ? 116.895 164.528 131.499 1.00 68.48  ? 249 ALA C CB    1 
ATOM   5403  N N     . ASN C 1 279 ? 118.494 165.031 134.164 1.00 68.99  ? 250 ASN C N     1 
ATOM   5404  C CA    . ASN C 1 279 ? 119.755 165.565 134.663 1.00 68.99  ? 250 ASN C CA    1 
ATOM   5405  C C     . ASN C 1 279 ? 120.212 164.959 135.986 1.00 68.99  ? 250 ASN C C     1 
ATOM   5406  O O     . ASN C 1 279 ? 121.390 165.097 136.331 1.00 68.99  ? 250 ASN C O     1 
ATOM   5407  C CB    . ASN C 1 279 ? 119.647 167.084 134.826 1.00 68.99  ? 250 ASN C CB    1 
ATOM   5408  C CG    . ASN C 1 279 ? 119.225 167.776 133.546 1.00 68.99  ? 250 ASN C CG    1 
ATOM   5409  O OD1   . ASN C 1 279 ? 118.878 167.124 132.561 1.00 68.99  ? 250 ASN C OD1   1 
ATOM   5410  N ND2   . ASN C 1 279 ? 119.254 169.102 133.552 1.00 68.99  ? 250 ASN C ND2   1 
ATOM   5411  N N     . ALA C 1 280 ? 119.333 164.299 136.735 1.00 73.84  ? 251 ALA C N     1 
ATOM   5412  C CA    . ALA C 1 280 ? 119.732 163.725 138.019 1.00 73.84  ? 251 ALA C CA    1 
ATOM   5413  C C     . ALA C 1 280 ? 120.640 162.519 137.815 1.00 73.84  ? 251 ALA C C     1 
ATOM   5414  O O     . ALA C 1 280 ? 120.241 161.518 137.219 1.00 73.84  ? 251 ALA C O     1 
ATOM   5415  C CB    . ALA C 1 280 ? 118.511 163.330 138.834 1.00 73.84  ? 251 ALA C CB    1 
ATOM   5416  N N     . LYS C 1 306 ? 116.584 165.784 143.147 1.00 74.69  ? 277 LYS C N     1 
ATOM   5417  C CA    . LYS C 1 306 ? 117.756 165.715 144.011 1.00 74.69  ? 277 LYS C CA    1 
ATOM   5418  C C     . LYS C 1 306 ? 118.545 167.020 143.950 1.00 74.69  ? 277 LYS C C     1 
ATOM   5419  O O     . LYS C 1 306 ? 118.961 167.550 144.982 1.00 74.69  ? 277 LYS C O     1 
ATOM   5420  C CB    . LYS C 1 306 ? 118.646 164.537 143.608 1.00 74.69  ? 277 LYS C CB    1 
ATOM   5421  C CG    . LYS C 1 306 ? 117.883 163.243 143.351 1.00 74.69  ? 277 LYS C CG    1 
ATOM   5422  C CD    . LYS C 1 306 ? 118.715 162.022 143.714 1.00 74.69  ? 277 LYS C CD    1 
ATOM   5423  C CE    . LYS C 1 306 ? 118.097 160.743 143.175 1.00 74.69  ? 277 LYS C CE    1 
ATOM   5424  N NZ    . LYS C 1 306 ? 118.809 160.248 141.965 1.00 74.69  ? 277 LYS C NZ    1 
ATOM   5425  N N     . LEU C 1 307 ? 118.735 167.522 142.729 1.00 75.44  ? 278 LEU C N     1 
ATOM   5426  C CA    . LEU C 1 307 ? 119.428 168.778 142.445 1.00 75.44  ? 278 LEU C CA    1 
ATOM   5427  C C     . LEU C 1 307 ? 118.437 169.823 141.931 1.00 75.44  ? 278 LEU C C     1 
ATOM   5428  O O     . LEU C 1 307 ? 118.740 170.629 141.049 1.00 75.44  ? 278 LEU C O     1 
ATOM   5429  C CB    . LEU C 1 307 ? 120.577 168.537 141.460 1.00 75.44  ? 278 LEU C CB    1 
ATOM   5430  C CG    . LEU C 1 307 ? 120.391 167.593 140.259 1.00 75.44  ? 278 LEU C CG    1 
ATOM   5431  C CD1   . LEU C 1 307 ? 119.245 167.997 139.335 1.00 75.44  ? 278 LEU C CD1   1 
ATOM   5432  C CD2   . LEU C 1 307 ? 121.693 167.499 139.475 1.00 75.44  ? 278 LEU C CD2   1 
ATOM   5433  N N     . ARG C 1 308 ? 117.235 169.814 142.510 1.00 70.60  ? 279 ARG C N     1 
ATOM   5434  C CA    . ARG C 1 308 ? 116.099 170.535 141.940 1.00 70.60  ? 279 ARG C CA    1 
ATOM   5435  C C     . ARG C 1 308 ? 116.266 172.050 142.002 1.00 70.60  ? 279 ARG C C     1 
ATOM   5436  O O     . ARG C 1 308 ? 115.730 172.757 141.140 1.00 70.60  ? 279 ARG C O     1 
ATOM   5437  C CB    . ARG C 1 308 ? 114.814 170.110 142.655 1.00 70.60  ? 279 ARG C CB    1 
ATOM   5438  C CG    . ARG C 1 308 ? 114.755 170.418 144.164 1.00 70.60  ? 279 ARG C CG    1 
ATOM   5439  C CD    . ARG C 1 308 ? 113.543 169.786 144.866 1.00 70.60  ? 279 ARG C CD    1 
ATOM   5440  N NE    . ARG C 1 308 ? 113.493 168.328 144.722 1.00 70.60  ? 279 ARG C NE    1 
ATOM   5441  C CZ    . ARG C 1 308 ? 113.138 167.443 145.650 1.00 70.60  ? 279 ARG C CZ    1 
ATOM   5442  N NH1   . ARG C 1 308 ? 112.713 167.804 146.853 1.00 70.60  ? 279 ARG C NH1   1 
ATOM   5443  N NH2   . ARG C 1 308 ? 113.196 166.147 145.358 1.00 70.60  ? 279 ARG C NH2   1 
ATOM   5444  N N     . GLN C 1 309 ? 116.952 172.563 143.028 1.00 76.33  ? 280 GLN C N     1 
ATOM   5445  C CA    . GLN C 1 309 ? 117.158 174.009 143.144 1.00 76.33  ? 280 GLN C CA    1 
ATOM   5446  C C     . GLN C 1 309 ? 117.937 174.560 141.952 1.00 76.33  ? 280 GLN C C     1 
ATOM   5447  O O     . GLN C 1 309 ? 117.638 175.653 141.458 1.00 76.33  ? 280 GLN C O     1 
ATOM   5448  C CB    . GLN C 1 309 ? 117.887 174.407 144.445 1.00 76.33  ? 280 GLN C CB    1 
ATOM   5449  C CG    . GLN C 1 309 ? 119.263 173.765 144.847 1.00 76.33  ? 280 GLN C CG    1 
ATOM   5450  C CD    . GLN C 1 309 ? 119.255 172.283 145.197 1.00 76.33  ? 280 GLN C CD    1 
ATOM   5451  O OE1   . GLN C 1 309 ? 118.443 171.833 146.005 1.00 76.33  ? 280 GLN C OE1   1 
ATOM   5452  N NE2   . GLN C 1 309 ? 120.162 171.523 144.596 1.00 76.33  ? 280 GLN C NE2   1 
ATOM   5453  N N     . GLU C 1 310 ? 118.942 173.822 141.479 1.00 78.90  ? 281 GLU C N     1 
ATOM   5454  C CA    . GLU C 1 310 ? 119.697 174.268 140.311 1.00 78.90  ? 281 GLU C CA    1 
ATOM   5455  C C     . GLU C 1 310 ? 118.828 174.257 139.058 1.00 78.90  ? 281 GLU C C     1 
ATOM   5456  O O     . GLU C 1 310 ? 118.950 175.144 138.198 1.00 78.90  ? 281 GLU C O     1 
ATOM   5457  C CB    . GLU C 1 310 ? 120.930 173.386 140.120 1.00 78.90  ? 281 GLU C CB    1 
ATOM   5458  C CG    . GLU C 1 310 ? 121.841 173.325 141.344 1.00 78.90  ? 281 GLU C CG    1 
ATOM   5459  C CD    . GLU C 1 310 ? 123.143 172.589 141.087 1.00 78.90  ? 281 GLU C CD    1 
ATOM   5460  O OE1   . GLU C 1 310 ? 123.644 172.628 139.944 1.00 78.90  ? 281 GLU C OE1   1 
ATOM   5461  O OE2   . GLU C 1 310 ? 123.665 171.968 142.036 1.00 78.90  ? 281 GLU C OE2   1 
ATOM   5462  N N     . ILE C 1 311 ? 117.942 173.263 138.945 1.00 75.38  ? 282 ILE C N     1 
ATOM   5463  C CA    . ILE C 1 311 ? 117.016 173.213 137.816 1.00 75.38  ? 282 ILE C CA    1 
ATOM   5464  C C     . ILE C 1 311 ? 116.086 174.420 137.864 1.00 75.38  ? 282 ILE C C     1 
ATOM   5465  O O     . ILE C 1 311 ? 115.804 175.052 136.835 1.00 75.38  ? 282 ILE C O     1 
ATOM   5466  C CB    . ILE C 1 311 ? 116.225 171.885 137.796 1.00 75.38  ? 282 ILE C CB    1 
ATOM   5467  C CG1   . ILE C 1 311 ? 117.141 170.645 137.938 1.00 75.38  ? 282 ILE C CG1   1 
ATOM   5468  C CG2   . ILE C 1 311 ? 115.376 171.787 136.513 1.00 75.38  ? 282 ILE C CG2   1 
ATOM   5469  C CD1   . ILE C 1 311 ? 118.312 170.571 136.965 1.00 75.38  ? 282 ILE C CD1   1 
ATOM   5470  N N     . ASN C 1 312 ? 115.623 174.769 139.069 1.00 74.34  ? 283 ASN C N     1 
ATOM   5471  C CA    . ASN C 1 312 ? 114.776 175.944 139.255 1.00 74.34  ? 283 ASN C CA    1 
ATOM   5472  C C     . ASN C 1 312 ? 115.513 177.223 138.869 1.00 74.34  ? 283 ASN C C     1 
ATOM   5473  O O     . ASN C 1 312 ? 114.939 178.117 138.236 1.00 74.34  ? 283 ASN C O     1 
ATOM   5474  C CB    . ASN C 1 312 ? 114.310 176.016 140.707 1.00 74.34  ? 283 ASN C CB    1 
ATOM   5475  C CG    . ASN C 1 312 ? 113.241 174.989 141.025 1.00 74.34  ? 283 ASN C CG    1 
ATOM   5476  O OD1   . ASN C 1 312 ? 113.191 173.920 140.416 1.00 74.34  ? 283 ASN C OD1   1 
ATOM   5477  N ND2   . ASN C 1 312 ? 112.375 175.311 141.979 1.00 74.34  ? 283 ASN C ND2   1 
ATOM   5478  N N     . LYS C 1 313 ? 116.791 177.322 139.241 1.00 78.62  ? 284 LYS C N     1 
ATOM   5479  C CA    . LYS C 1 313 ? 117.568 178.517 138.920 1.00 78.62  ? 284 LYS C CA    1 
ATOM   5480  C C     . LYS C 1 313 ? 117.753 178.676 137.415 1.00 78.62  ? 284 LYS C C     1 
ATOM   5481  O O     . LYS C 1 313 ? 117.599 179.782 136.875 1.00 78.62  ? 284 LYS C O     1 
ATOM   5482  C CB    . LYS C 1 313 ? 118.929 178.462 139.619 1.00 78.62  ? 284 LYS C CB    1 
ATOM   5483  C CG    . LYS C 1 313 ? 118.920 178.901 141.087 1.00 78.62  ? 284 LYS C CG    1 
ATOM   5484  C CD    . LYS C 1 313 ? 120.267 179.464 141.513 1.00 78.62  ? 284 LYS C CD    1 
ATOM   5485  C CE    . LYS C 1 313 ? 120.424 180.925 141.113 1.00 78.62  ? 284 LYS C CE    1 
ATOM   5486  N NZ    . LYS C 1 313 ? 121.838 181.371 141.219 1.00 78.62  ? 284 LYS C NZ    1 
ATOM   5487  N N     . VAL C 1 314 ? 118.075 177.584 136.713 1.00 79.30  ? 285 VAL C N     1 
ATOM   5488  C CA    . VAL C 1 314 ? 118.314 177.710 135.275 1.00 79.30  ? 285 VAL C CA    1 
ATOM   5489  C C     . VAL C 1 314 ? 117.010 177.995 134.530 1.00 79.30  ? 285 VAL C C     1 
ATOM   5490  O O     . VAL C 1 314 ? 117.005 178.775 133.571 1.00 79.30  ? 285 VAL C O     1 
ATOM   5491  C CB    . VAL C 1 314 ? 119.057 176.483 134.698 1.00 79.30  ? 285 VAL C CB    1 
ATOM   5492  C CG1   . VAL C 1 314 ? 118.262 175.203 134.812 1.00 79.30  ? 285 VAL C CG1   1 
ATOM   5493  C CG2   . VAL C 1 314 ? 119.450 176.725 133.236 1.00 79.30  ? 285 VAL C CG2   1 
ATOM   5494  N N     . VAL C 1 315 ? 115.887 177.381 134.941 1.00 76.81  ? 286 VAL C N     1 
ATOM   5495  C CA    . VAL C 1 315 ? 114.634 177.705 134.244 1.00 76.81  ? 286 VAL C CA    1 
ATOM   5496  C C     . VAL C 1 315 ? 114.217 179.138 134.564 1.00 76.81  ? 286 VAL C C     1 
ATOM   5497  O O     . VAL C 1 315 ? 113.584 179.805 133.733 1.00 76.81  ? 286 VAL C O     1 
ATOM   5498  C CB    . VAL C 1 315 ? 113.463 176.741 134.550 1.00 76.81  ? 286 VAL C CB    1 
ATOM   5499  C CG1   . VAL C 1 315 ? 113.659 175.393 133.848 1.00 76.81  ? 286 VAL C CG1   1 
ATOM   5500  C CG2   . VAL C 1 315 ? 113.115 176.641 136.026 1.00 76.81  ? 286 VAL C CG2   1 
ATOM   5501  N N     . ASN C 1 316 ? 114.550 179.636 135.764 1.00 78.71  ? 287 ASN C N     1 
ATOM   5502  C CA    . ASN C 1 316 ? 114.311 181.045 136.067 1.00 78.71  ? 287 ASN C CA    1 
ATOM   5503  C C     . ASN C 1 316 ? 115.113 181.950 135.140 1.00 78.71  ? 287 ASN C C     1 
ATOM   5504  O O     . ASN C 1 316 ? 114.594 182.954 134.642 1.00 78.71  ? 287 ASN C O     1 
ATOM   5505  C CB    . ASN C 1 316 ? 114.654 181.346 137.527 1.00 78.71  ? 287 ASN C CB    1 
ATOM   5506  C CG    . ASN C 1 316 ? 113.452 181.235 138.442 1.00 78.71  ? 287 ASN C CG    1 
ATOM   5507  O OD1   . ASN C 1 316 ? 112.566 182.090 138.426 1.00 78.71  ? 287 ASN C OD1   1 
ATOM   5508  N ND2   . ASN C 1 316 ? 113.415 180.181 139.249 1.00 78.71  ? 287 ASN C ND2   1 
ATOM   5509  N N     . ARG C 1 317 ? 116.381 181.606 134.895 1.00 83.09  ? 288 ARG C N     1 
ATOM   5510  C CA    . ARG C 1 317 ? 117.182 182.379 133.944 1.00 83.09  ? 288 ARG C CA    1 
ATOM   5511  C C     . ARG C 1 317 ? 116.593 182.308 132.538 1.00 83.09  ? 288 ARG C C     1 
ATOM   5512  O O     . ARG C 1 317 ? 116.568 183.313 131.815 1.00 83.09  ? 288 ARG C O     1 
ATOM   5513  C CB    . ARG C 1 317 ? 118.628 181.883 133.935 1.00 83.09  ? 288 ARG C CB    1 
ATOM   5514  C CG    . ARG C 1 317 ? 119.520 182.531 134.983 1.00 83.09  ? 288 ARG C CG    1 
ATOM   5515  C CD    . ARG C 1 317 ? 120.647 181.604 135.421 1.00 83.09  ? 288 ARG C CD    1 
ATOM   5516  N NE    . ARG C 1 317 ? 121.318 180.966 134.291 1.00 83.09  ? 288 ARG C NE    1 
ATOM   5517  C CZ    . ARG C 1 317 ? 122.178 179.956 134.375 1.00 83.09  ? 288 ARG C CZ    1 
ATOM   5518  N NH1   . ARG C 1 317 ? 122.533 179.426 135.539 1.00 83.09  ? 288 ARG C NH1   1 
ATOM   5519  N NH2   . ARG C 1 317 ? 122.701 179.460 133.257 1.00 83.09  ? 288 ARG C NH2   1 
ATOM   5520  N N     . TYR C 1 318 ? 116.113 181.124 132.142 1.00 83.06  ? 289 TYR C N     1 
ATOM   5521  C CA    . TYR C 1 318 ? 115.520 180.944 130.816 1.00 83.06  ? 289 TYR C CA    1 
ATOM   5522  C C     . TYR C 1 318 ? 114.292 181.829 130.635 1.00 83.06  ? 289 TYR C C     1 
ATOM   5523  O O     . TYR C 1 318 ? 114.172 182.545 129.634 1.00 83.06  ? 289 TYR C O     1 
ATOM   5524  C CB    . TYR C 1 318 ? 115.134 179.477 130.599 1.00 83.06  ? 289 TYR C CB    1 
ATOM   5525  C CG    . TYR C 1 318 ? 116.152 178.640 129.852 1.00 83.06  ? 289 TYR C CG    1 
ATOM   5526  C CD1   . TYR C 1 318 ? 116.248 178.697 128.471 1.00 83.06  ? 289 TYR C CD1   1 
ATOM   5527  C CD2   . TYR C 1 318 ? 117.009 177.783 130.530 1.00 83.06  ? 289 TYR C CD2   1 
ATOM   5528  C CE1   . TYR C 1 318 ? 117.169 177.932 127.783 1.00 83.06  ? 289 TYR C CE1   1 
ATOM   5529  C CE2   . TYR C 1 318 ? 117.935 177.014 129.852 1.00 83.06  ? 289 TYR C CE2   1 
ATOM   5530  C CZ    . TYR C 1 318 ? 118.011 177.093 128.478 1.00 83.06  ? 289 TYR C CZ    1 
ATOM   5531  O OH    . TYR C 1 318 ? 118.930 176.332 127.794 1.00 83.06  ? 289 TYR C OH    1 
ATOM   5532  N N     . ILE C 1 319 ? 113.370 181.798 131.602 1.00 82.75  ? 290 ILE C N     1 
ATOM   5533  C CA    . ILE C 1 319 ? 112.136 182.569 131.456 1.00 82.75  ? 290 ILE C CA    1 
ATOM   5534  C C     . ILE C 1 319 ? 112.399 184.063 131.623 1.00 82.75  ? 290 ILE C C     1 
ATOM   5535  O O     . ILE C 1 319 ? 111.724 184.886 130.992 1.00 82.75  ? 290 ILE C O     1 
ATOM   5536  C CB    . ILE C 1 319 ? 111.044 182.065 132.425 1.00 82.75  ? 290 ILE C CB    1 
ATOM   5537  C CG1   . ILE C 1 319 ? 109.684 182.680 132.064 1.00 82.75  ? 290 ILE C CG1   1 
ATOM   5538  C CG2   . ILE C 1 319 ? 111.386 182.366 133.883 1.00 82.75  ? 290 ILE C CG2   1 
ATOM   5539  C CD1   . ILE C 1 319 ? 108.516 182.000 132.733 1.00 82.75  ? 290 ILE C CD1   1 
ATOM   5540  N N     . ASP C 1 320 ? 113.362 184.448 132.469 1.00 88.35  ? 291 ASP C N     1 
ATOM   5541  C CA    . ASP C 1 320 ? 113.712 185.861 132.574 1.00 88.35  ? 291 ASP C CA    1 
ATOM   5542  C C     . ASP C 1 320 ? 114.339 186.375 131.285 1.00 88.35  ? 291 ASP C C     1 
ATOM   5543  O O     . ASP C 1 320 ? 114.139 187.541 130.925 1.00 88.35  ? 291 ASP C O     1 
ATOM   5544  C CB    . ASP C 1 320 ? 114.663 186.086 133.752 1.00 88.35  ? 291 ASP C CB    1 
ATOM   5545  C CG    . ASP C 1 320 ? 113.996 185.865 135.104 1.00 88.35  ? 291 ASP C CG    1 
ATOM   5546  O OD1   . ASP C 1 320 ? 112.752 185.926 135.191 1.00 88.35  ? 291 ASP C OD1   1 
ATOM   5547  O OD2   . ASP C 1 320 ? 114.727 185.623 136.088 1.00 88.35  ? 291 ASP C OD2   1 
ATOM   5548  N N     . GLU C 1 321 ? 115.094 185.529 130.580 1.00 90.30  ? 292 GLU C N     1 
ATOM   5549  C CA    . GLU C 1 321 ? 115.613 185.925 129.272 1.00 90.30  ? 292 GLU C CA    1 
ATOM   5550  C C     . GLU C 1 321 ? 114.521 186.012 128.208 1.00 90.30  ? 292 GLU C C     1 
ATOM   5551  O O     . GLU C 1 321 ? 114.747 186.637 127.166 1.00 90.30  ? 292 GLU C O     1 
ATOM   5552  C CB    . GLU C 1 321 ? 116.704 184.956 128.803 1.00 90.30  ? 292 GLU C CB    1 
ATOM   5553  C CG    . GLU C 1 321 ? 118.115 185.492 128.982 1.00 90.30  ? 292 GLU C CG    1 
ATOM   5554  C CD    . GLU C 1 321 ? 119.166 184.401 128.934 1.00 90.30  ? 292 GLU C CD    1 
ATOM   5555  O OE1   . GLU C 1 321 ? 119.120 183.571 128.002 1.00 90.30  ? 292 GLU C OE1   1 
ATOM   5556  O OE2   . GLU C 1 321 ? 120.039 184.374 129.826 1.00 90.30  ? 292 GLU C OE2   1 
ATOM   5557  N N     . GLY C 1 322 ? 113.353 185.401 128.434 1.00 89.05  ? 293 GLY C N     1 
ATOM   5558  C CA    . GLY C 1 322 ? 112.249 185.463 127.500 1.00 89.05  ? 293 GLY C CA    1 
ATOM   5559  C C     . GLY C 1 322 ? 112.258 184.411 126.409 1.00 89.05  ? 293 GLY C C     1 
ATOM   5560  O O     . GLY C 1 322 ? 111.277 184.313 125.661 1.00 89.05  ? 293 GLY C O     1 
ATOM   5561  N N     . VAL C 1 323 ? 113.329 183.621 126.290 1.00 89.05  ? 294 VAL C N     1 
ATOM   5562  C CA    . VAL C 1 323 ? 113.362 182.551 125.294 1.00 89.05  ? 294 VAL C CA    1 
ATOM   5563  C C     . VAL C 1 323 ? 112.340 181.452 125.578 1.00 89.05  ? 294 VAL C C     1 
ATOM   5564  O O     . VAL C 1 323 ? 111.963 180.725 124.652 1.00 89.05  ? 294 VAL C O     1 
ATOM   5565  C CB    . VAL C 1 323 ? 114.776 181.936 125.167 1.00 89.05  ? 294 VAL C CB    1 
ATOM   5566  C CG1   . VAL C 1 323 ? 115.732 182.936 124.534 1.00 89.05  ? 294 VAL C CG1   1 
ATOM   5567  C CG2   . VAL C 1 323 ? 115.339 181.443 126.518 1.00 89.05  ? 294 VAL C CG2   1 
ATOM   5568  N N     . ALA C 1 324 ? 111.905 181.292 126.832 1.00 83.87  ? 295 ALA C N     1 
ATOM   5569  C CA    . ALA C 1 324 ? 110.943 180.274 127.237 1.00 83.87  ? 295 ALA C CA    1 
ATOM   5570  C C     . ALA C 1 324 ? 109.893 180.900 128.146 1.00 83.87  ? 295 ALA C C     1 
ATOM   5571  O O     . ALA C 1 324 ? 110.062 182.009 128.659 1.00 83.87  ? 295 ALA C O     1 
ATOM   5572  C CB    . ALA C 1 324 ? 111.633 179.104 127.950 1.00 83.87  ? 295 ALA C CB    1 
ATOM   5573  N N     . GLU C 1 325 ? 108.795 180.163 128.328 1.00 75.59  ? 296 GLU C N     1 
ATOM   5574  C CA    . GLU C 1 325 ? 107.661 180.590 129.137 1.00 75.59  ? 296 GLU C CA    1 
ATOM   5575  C C     . GLU C 1 325 ? 107.222 179.423 130.011 1.00 75.59  ? 296 GLU C C     1 
ATOM   5576  O O     . GLU C 1 325 ? 107.416 178.260 129.653 1.00 75.59  ? 296 GLU C O     1 
ATOM   5577  C CB    . GLU C 1 325 ? 106.502 181.074 128.246 1.00 75.59  ? 296 GLU C CB    1 
ATOM   5578  C CG    . GLU C 1 325 ? 105.247 181.514 128.989 1.00 75.59  ? 296 GLU C CG    1 
ATOM   5579  C CD    . GLU C 1 325 ? 104.276 182.262 128.099 1.00 75.59  ? 296 GLU C CD    1 
ATOM   5580  O OE1   . GLU C 1 325 ? 104.252 181.987 126.882 1.00 75.59  ? 296 GLU C OE1   1 
ATOM   5581  O OE2   . GLU C 1 325 ? 103.536 183.124 128.618 1.00 75.59  ? 296 GLU C OE2   1 
ATOM   5582  N N     . LEU C 1 326 ? 106.647 179.750 131.170 1.00 63.85  ? 297 LEU C N     1 
ATOM   5583  C CA    . LEU C 1 326 ? 106.133 178.780 132.129 1.00 63.85  ? 297 LEU C CA    1 
ATOM   5584  C C     . LEU C 1 326 ? 104.613 178.824 132.143 1.00 63.85  ? 297 LEU C C     1 
ATOM   5585  O O     . LEU C 1 326 ? 104.016 179.898 132.017 1.00 63.85  ? 297 LEU C O     1 
ATOM   5586  C CB    . LEU C 1 326 ? 106.672 179.066 133.533 1.00 63.85  ? 297 LEU C CB    1 
ATOM   5587  C CG    . LEU C 1 326 ? 106.313 178.074 134.644 1.00 63.85  ? 297 LEU C CG    1 
ATOM   5588  C CD1   . LEU C 1 326 ? 107.529 177.816 135.513 1.00 63.85  ? 297 LEU C CD1   1 
ATOM   5589  C CD2   . LEU C 1 326 ? 105.161 178.579 135.507 1.00 63.85  ? 297 LEU C CD2   1 
ATOM   5590  N N     . VAL C 1 327 ? 104.003 177.649 132.283 1.00 55.75  ? 298 VAL C N     1 
ATOM   5591  C CA    . VAL C 1 327 ? 102.571 177.476 132.492 1.00 55.75  ? 298 VAL C CA    1 
ATOM   5592  C C     . VAL C 1 327 ? 102.400 176.719 133.812 1.00 55.75  ? 298 VAL C C     1 
ATOM   5593  O O     . VAL C 1 327 ? 102.939 175.614 133.959 1.00 55.75  ? 298 VAL C O     1 
ATOM   5594  C CB    . VAL C 1 327 ? 101.884 176.738 131.328 1.00 55.75  ? 298 VAL C CB    1 
ATOM   5595  C CG1   . VAL C 1 327 ? 101.794 177.658 130.108 1.00 55.75  ? 298 VAL C CG1   1 
ATOM   5596  C CG2   . VAL C 1 327 ? 102.580 175.419 130.941 1.00 55.75  ? 298 VAL C CG2   1 
ATOM   5597  N N     . PRO C 1 328 ? 101.727 177.270 134.833 1.00 49.35  ? 299 PRO C N     1 
ATOM   5598  C CA    . PRO C 1 328 ? 101.472 176.459 136.037 1.00 49.35  ? 299 PRO C CA    1 
ATOM   5599  C C     . PRO C 1 328 ? 100.292 175.527 135.804 1.00 49.35  ? 299 PRO C C     1 
ATOM   5600  O O     . PRO C 1 328 ? 99.195  175.973 135.461 1.00 49.35  ? 299 PRO C O     1 
ATOM   5601  C CB    . PRO C 1 328 ? 101.163 177.502 137.120 1.00 49.35  ? 299 PRO C CB    1 
ATOM   5602  C CG    . PRO C 1 328 ? 101.297 178.826 136.506 1.00 49.35  ? 299 PRO C CG    1 
ATOM   5603  C CD    . PRO C 1 328 ? 101.278 178.662 135.040 1.00 49.35  ? 299 PRO C CD    1 
ATOM   5604  N N     . GLY C 1 329 ? 100.521 174.233 135.990 1.00 42.56  ? 300 GLY C N     1 
ATOM   5605  C CA    . GLY C 1 329 ? 99.479  173.241 135.839 1.00 42.56  ? 300 GLY C CA    1 
ATOM   5606  C C     . GLY C 1 329 ? 98.632  173.131 137.085 1.00 42.56  ? 300 GLY C C     1 
ATOM   5607  O O     . GLY C 1 329 ? 98.558  174.048 137.906 1.00 42.56  ? 300 GLY C O     1 
ATOM   5608  N N     . VAL C 1 330 ? 97.982  171.978 137.218 1.00 36.25  ? 301 VAL C N     1 
ATOM   5609  C CA    . VAL C 1 330 ? 97.033  171.700 138.289 1.00 36.25  ? 301 VAL C CA    1 
ATOM   5610  C C     . VAL C 1 330 ? 97.435  170.374 138.911 1.00 36.25  ? 301 VAL C C     1 
ATOM   5611  O O     . VAL C 1 330 ? 97.290  169.319 138.279 1.00 36.25  ? 301 VAL C O     1 
ATOM   5612  C CB    . VAL C 1 330 ? 95.586  171.655 137.776 1.00 36.25  ? 301 VAL C CB    1 
ATOM   5613  C CG1   . VAL C 1 330 ? 94.641  171.091 138.830 1.00 36.25  ? 301 VAL C CG1   1 
ATOM   5614  C CG2   . VAL C 1 330 ? 95.119  173.040 137.354 1.00 36.25  ? 301 VAL C CG2   1 
ATOM   5615  N N     . LEU C 1 331 ? 97.930  170.423 140.147 1.00 37.74  ? 302 LEU C N     1 
ATOM   5616  C CA    . LEU C 1 331 ? 98.225  169.223 140.927 1.00 37.74  ? 302 LEU C CA    1 
ATOM   5617  C C     . LEU C 1 331 ? 96.977  168.905 141.735 1.00 37.74  ? 302 LEU C C     1 
ATOM   5618  O O     . LEU C 1 331 ? 96.736  169.515 142.778 1.00 37.74  ? 302 LEU C O     1 
ATOM   5619  C CB    . LEU C 1 331 ? 99.437  169.447 141.825 1.00 37.74  ? 302 LEU C CB    1 
ATOM   5620  C CG    . LEU C 1 331 ? 99.840  168.364 142.835 1.00 37.74  ? 302 LEU C CG    1 
ATOM   5621  C CD1   . LEU C 1 331 ? 100.404 167.162 142.117 1.00 37.74  ? 302 LEU C CD1   1 
ATOM   5622  C CD2   . LEU C 1 331 ? 100.845 168.926 143.821 1.00 37.74  ? 302 LEU C CD2   1 
ATOM   5623  N N     . PHE C 1 332 ? 96.179  167.953 141.256 1.00 34.07  ? 303 PHE C N     1 
ATOM   5624  C CA    . PHE C 1 332 ? 94.988  167.516 141.971 1.00 34.07  ? 303 PHE C CA    1 
ATOM   5625  C C     . PHE C 1 332 ? 95.369  166.383 142.914 1.00 34.07  ? 303 PHE C C     1 
ATOM   5626  O O     . PHE C 1 332 ? 95.989  165.404 142.488 1.00 34.07  ? 303 PHE C O     1 
ATOM   5627  C CB    . PHE C 1 332 ? 93.894  167.065 141.006 1.00 34.07  ? 303 PHE C CB    1 
ATOM   5628  C CG    . PHE C 1 332 ? 92.628  166.639 141.690 1.00 34.07  ? 303 PHE C CG    1 
ATOM   5629  C CD1   . PHE C 1 332 ? 91.718  167.580 142.129 1.00 34.07  ? 303 PHE C CD1   1 
ATOM   5630  C CD2   . PHE C 1 332 ? 92.346  165.302 141.892 1.00 34.07  ? 303 PHE C CD2   1 
ATOM   5631  C CE1   . PHE C 1 332 ? 90.556  167.199 142.755 1.00 34.07  ? 303 PHE C CE1   1 
ATOM   5632  C CE2   . PHE C 1 332 ? 91.184  164.915 142.522 1.00 34.07  ? 303 PHE C CE2   1 
ATOM   5633  C CZ    . PHE C 1 332 ? 90.289  165.866 142.953 1.00 34.07  ? 303 PHE C CZ    1 
ATOM   5634  N N     . ILE C 1 333 ? 95.012  166.530 144.190 1.00 39.39  ? 304 ILE C N     1 
ATOM   5635  C CA    . ILE C 1 333 ? 95.330  165.558 145.238 1.00 39.39  ? 304 ILE C CA    1 
ATOM   5636  C C     . ILE C 1 333 ? 94.008  165.155 145.878 1.00 39.39  ? 304 ILE C C     1 
ATOM   5637  O O     . ILE C 1 333 ? 93.441  165.907 146.681 1.00 39.39  ? 304 ILE C O     1 
ATOM   5638  C CB    . ILE C 1 333 ? 96.310  166.115 146.280 1.00 39.39  ? 304 ILE C CB    1 
ATOM   5639  C CG1   . ILE C 1 333 ? 97.681  166.406 145.645 1.00 39.39  ? 304 ILE C CG1   1 
ATOM   5640  C CG2   . ILE C 1 333 ? 96.450  165.132 147.456 1.00 39.39  ? 304 ILE C CG2   1 
ATOM   5641  C CD1   . ILE C 1 333 ? 98.591  167.299 146.475 1.00 39.39  ? 304 ILE C CD1   1 
ATOM   5642  N N     . ASP C 1 334 ? 93.514  163.971 145.525 1.00 41.33  ? 305 ASP C N     1 
ATOM   5643  C CA    . ASP C 1 334 ? 92.343  163.399 146.167 1.00 41.33  ? 305 ASP C CA    1 
ATOM   5644  C C     . ASP C 1 334 ? 92.749  162.692 147.454 1.00 41.33  ? 305 ASP C C     1 
ATOM   5645  O O     . ASP C 1 334 ? 93.892  162.259 147.616 1.00 41.33  ? 305 ASP C O     1 
ATOM   5646  C CB    . ASP C 1 334 ? 91.641  162.421 145.227 1.00 41.33  ? 305 ASP C CB    1 
ATOM   5647  C CG    . ASP C 1 334 ? 90.134  162.460 145.364 1.00 41.33  ? 305 ASP C CG    1 
ATOM   5648  O OD1   . ASP C 1 334 ? 89.616  161.988 146.398 1.00 41.33  ? 305 ASP C OD1   1 
ATOM   5649  O OD2   . ASP C 1 334 ? 89.466  162.962 144.437 1.00 41.33  ? 305 ASP C OD2   1 
ATOM   5650  N N     . GLU C 1 335 ? 91.790  162.582 148.376 1.00 46.49  ? 306 GLU C N     1 
ATOM   5651  C CA    . GLU C 1 335 ? 92.000  161.959 149.685 1.00 46.49  ? 306 GLU C CA    1 
ATOM   5652  C C     . GLU C 1 335 ? 93.116  162.676 150.448 1.00 46.49  ? 306 GLU C C     1 
ATOM   5653  O O     . GLU C 1 335 ? 94.129  162.086 150.827 1.00 46.49  ? 306 GLU C O     1 
ATOM   5654  C CB    . GLU C 1 335 ? 92.305  160.459 149.554 1.00 46.49  ? 306 GLU C CB    1 
ATOM   5655  C CG    . GLU C 1 335 ? 91.239  159.620 148.844 1.00 46.49  ? 306 GLU C CG    1 
ATOM   5656  C CD    . GLU C 1 335 ? 90.141  159.157 149.779 1.00 46.49  ? 306 GLU C CD    1 
ATOM   5657  O OE1   . GLU C 1 335 ? 89.277  159.981 150.143 1.00 46.49  ? 306 GLU C OE1   1 
ATOM   5658  O OE2   . GLU C 1 335 ? 90.142  157.964 150.149 1.00 46.49  ? 306 GLU C OE2   1 
ATOM   5659  N N     . VAL C 1 336 ? 92.914  163.981 150.649 1.00 43.34  ? 307 VAL C N     1 
ATOM   5660  C CA    . VAL C 1 336 ? 93.944  164.811 151.266 1.00 43.34  ? 307 VAL C CA    1 
ATOM   5661  C C     . VAL C 1 336 ? 94.182  164.414 152.718 1.00 43.34  ? 307 VAL C C     1 
ATOM   5662  O O     . VAL C 1 336 ? 95.291  164.587 153.235 1.00 43.34  ? 307 VAL C O     1 
ATOM   5663  C CB    . VAL C 1 336 ? 93.573  166.301 151.141 1.00 43.34  ? 307 VAL C CB    1 
ATOM   5664  C CG1   . VAL C 1 336 ? 92.435  166.670 152.085 1.00 43.34  ? 307 VAL C CG1   1 
ATOM   5665  C CG2   . VAL C 1 336 ? 94.786  167.177 151.400 1.00 43.34  ? 307 VAL C CG2   1 
ATOM   5666  N N     . HIS C 1 337 ? 93.163  163.883 153.400 1.00 50.55  ? 308 HIS C N     1 
ATOM   5667  C CA    . HIS C 1 337 ? 93.328  163.471 154.792 1.00 50.55  ? 308 HIS C CA    1 
ATOM   5668  C C     . HIS C 1 337 ? 94.325  162.330 154.963 1.00 50.55  ? 308 HIS C C     1 
ATOM   5669  O O     . HIS C 1 337 ? 94.856  162.152 156.064 1.00 50.55  ? 308 HIS C O     1 
ATOM   5670  C CB    . HIS C 1 337 ? 91.983  163.054 155.390 1.00 50.55  ? 308 HIS C CB    1 
ATOM   5671  C CG    . HIS C 1 337 ? 91.340  161.894 154.695 1.00 50.55  ? 308 HIS C CG    1 
ATOM   5672  N ND1   . HIS C 1 337 ? 90.535  162.045 153.587 1.00 50.55  ? 308 HIS C ND1   1 
ATOM   5673  C CD2   . HIS C 1 337 ? 91.386  160.564 154.948 1.00 50.55  ? 308 HIS C CD2   1 
ATOM   5674  C CE1   . HIS C 1 337 ? 90.111  160.860 153.188 1.00 50.55  ? 308 HIS C CE1   1 
ATOM   5675  N NE2   . HIS C 1 337 ? 90.612  159.944 153.997 1.00 50.55  ? 308 HIS C NE2   1 
ATOM   5676  N N     . MET C 1 338 ? 94.593  161.551 153.911 1.00 55.24  ? 309 MET C N     1 
ATOM   5677  C CA    . MET C 1 338 ? 95.556  160.462 154.020 1.00 55.24  ? 309 MET C CA    1 
ATOM   5678  C C     . MET C 1 338 ? 96.994  160.957 154.148 1.00 55.24  ? 309 MET C C     1 
ATOM   5679  O O     . MET C 1 338 ? 97.852  160.196 154.606 1.00 55.24  ? 309 MET C O     1 
ATOM   5680  C CB    . MET C 1 338 ? 95.443  159.540 152.797 1.00 55.24  ? 309 MET C CB    1 
ATOM   5681  C CG    . MET C 1 338 ? 95.759  158.053 153.015 1.00 55.24  ? 309 MET C CG    1 
ATOM   5682  S SD    . MET C 1 338 ? 94.813  157.201 154.299 1.00 55.24  ? 309 MET C SD    1 
ATOM   5683  C CE    . MET C 1 338 ? 93.541  156.407 153.320 1.00 55.24  ? 309 MET C CE    1 
ATOM   5684  N N     . LEU C 1 339 ? 97.281  162.199 153.758 1.00 52.19  ? 310 LEU C N     1 
ATOM   5685  C CA    . LEU C 1 339 ? 98.643  162.710 153.826 1.00 52.19  ? 310 LEU C CA    1 
ATOM   5686  C C     . LEU C 1 339 ? 99.090  162.878 155.273 1.00 52.19  ? 310 LEU C C     1 
ATOM   5687  O O     . LEU C 1 339 ? 98.307  163.269 156.141 1.00 52.19  ? 310 LEU C O     1 
ATOM   5688  C CB    . LEU C 1 339 ? 98.741  164.054 153.102 1.00 52.19  ? 310 LEU C CB    1 
ATOM   5689  C CG    . LEU C 1 339 ? 98.520  164.122 151.589 1.00 52.19  ? 310 LEU C CG    1 
ATOM   5690  C CD1   . LEU C 1 339 ? 98.748  165.543 151.110 1.00 52.19  ? 310 LEU C CD1   1 
ATOM   5691  C CD2   . LEU C 1 339 ? 99.426  163.171 150.837 1.00 52.19  ? 310 LEU C CD2   1 
ATOM   5692  N N     . ASP C 1 340 ? 100.368 162.604 155.521 1.00 62.57  ? 311 ASP C N     1 
ATOM   5693  C CA    . ASP C 1 340 ? 100.941 162.708 156.854 1.00 62.57  ? 311 ASP C CA    1 
ATOM   5694  C C     . ASP C 1 340 ? 101.213 164.169 157.211 1.00 62.57  ? 311 ASP C C     1 
ATOM   5695  O O     . ASP C 1 340 ? 101.123 165.071 156.375 1.00 62.57  ? 311 ASP C O     1 
ATOM   5696  C CB    . ASP C 1 340 ? 102.228 161.888 156.937 1.00 62.57  ? 311 ASP C CB    1 
ATOM   5697  C CG    . ASP C 1 340 ? 102.494 161.357 158.330 1.00 62.57  ? 311 ASP C CG    1 
ATOM   5698  O OD1   . ASP C 1 340 ? 102.305 162.116 159.302 1.00 62.57  ? 311 ASP C OD1   1 
ATOM   5699  O OD2   . ASP C 1 340 ? 102.890 160.179 158.453 1.00 62.57  ? 311 ASP C OD2   1 
ATOM   5700  N N     . MET C 1 341 ? 101.544 164.400 158.485 1.00 64.31  ? 312 MET C N     1 
ATOM   5701  C CA    . MET C 1 341 ? 101.842 165.756 158.938 1.00 64.31  ? 312 MET C CA    1 
ATOM   5702  C C     . MET C 1 341 ? 103.119 166.275 158.285 1.00 64.31  ? 312 MET C C     1 
ATOM   5703  O O     . MET C 1 341 ? 103.226 167.471 157.983 1.00 64.31  ? 312 MET C O     1 
ATOM   5704  C CB    . MET C 1 341 ? 101.947 165.776 160.468 1.00 64.31  ? 312 MET C CB    1 
ATOM   5705  C CG    . MET C 1 341 ? 102.219 167.140 161.128 1.00 64.31  ? 312 MET C CG    1 
ATOM   5706  S SD    . MET C 1 341 ? 100.762 168.202 161.144 1.00 64.31  ? 312 MET C SD    1 
ATOM   5707  C CE    . MET C 1 341 ? 99.833  167.489 162.500 1.00 64.31  ? 312 MET C CE    1 
ATOM   5708  N N     . GLU C 1 342 ? 104.100 165.390 158.075 1.00 62.19  ? 313 GLU C N     1 
ATOM   5709  C CA    . GLU C 1 342 ? 105.299 165.769 157.335 1.00 62.19  ? 313 GLU C CA    1 
ATOM   5710  C C     . GLU C 1 342 ? 104.946 166.199 155.918 1.00 62.19  ? 313 GLU C C     1 
ATOM   5711  O O     . GLU C 1 342 ? 105.486 167.187 155.408 1.00 62.19  ? 313 GLU C O     1 
ATOM   5712  C CB    . GLU C 1 342 ? 106.292 164.602 157.315 1.00 62.19  ? 313 GLU C CB    1 
ATOM   5713  C CG    . GLU C 1 342 ? 107.419 164.724 156.268 1.00 62.19  ? 313 GLU C CG    1 
ATOM   5714  C CD    . GLU C 1 342 ? 108.625 163.838 156.554 1.00 62.19  ? 313 GLU C CD    1 
ATOM   5715  O OE1   . GLU C 1 342 ? 108.979 163.640 157.735 1.00 62.19  ? 313 GLU C OE1   1 
ATOM   5716  O OE2   . GLU C 1 342 ? 109.227 163.336 155.582 1.00 62.19  ? 313 GLU C OE2   1 
ATOM   5717  N N     . CYS C 1 343 ? 104.026 165.473 155.278 1.00 58.41  ? 314 CYS C N     1 
ATOM   5718  C CA    . CYS C 1 343 ? 103.592 165.822 153.930 1.00 58.41  ? 314 CYS C CA    1 
ATOM   5719  C C     . CYS C 1 343 ? 102.918 167.187 153.899 1.00 58.41  ? 314 CYS C C     1 
ATOM   5720  O O     . CYS C 1 343 ? 103.195 168.005 153.013 1.00 58.41  ? 314 CYS C O     1 
ATOM   5721  C CB    . CYS C 1 343 ? 102.637 164.751 153.410 1.00 58.41  ? 314 CYS C CB    1 
ATOM   5722  S SG    . CYS C 1 343 ? 103.299 163.071 153.461 1.00 58.41  ? 314 CYS C SG    1 
ATOM   5723  N N     . PHE C 1 344 ? 102.037 167.452 154.868 1.00 54.21  ? 315 PHE C N     1 
ATOM   5724  C CA    . PHE C 1 344 ? 101.332 168.729 154.914 1.00 54.21  ? 315 PHE C CA    1 
ATOM   5725  C C     . PHE C 1 344 ? 102.297 169.882 155.145 1.00 54.21  ? 315 PHE C C     1 
ATOM   5726  O O     . PHE C 1 344 ? 102.209 170.920 154.478 1.00 54.21  ? 315 PHE C O     1 
ATOM   5727  C CB    . PHE C 1 344 ? 100.279 168.712 156.024 1.00 54.21  ? 315 PHE C CB    1 
ATOM   5728  C CG    . PHE C 1 344 ? 99.014  167.979 155.677 1.00 54.21  ? 315 PHE C CG    1 
ATOM   5729  C CD1   . PHE C 1 344 ? 98.187  168.420 154.661 1.00 54.21  ? 315 PHE C CD1   1 
ATOM   5730  C CD2   . PHE C 1 344 ? 98.626  166.873 156.410 1.00 54.21  ? 315 PHE C CD2   1 
ATOM   5731  C CE1   . PHE C 1 344 ? 97.027  167.757 154.360 1.00 54.21  ? 315 PHE C CE1   1 
ATOM   5732  C CE2   . PHE C 1 344 ? 97.459  166.208 156.115 1.00 54.21  ? 315 PHE C CE2   1 
ATOM   5733  C CZ    . PHE C 1 344 ? 96.659  166.651 155.090 1.00 54.21  ? 315 PHE C CZ    1 
ATOM   5734  N N     . SER C 1 345 ? 103.224 169.717 156.091 1.00 57.90  ? 316 SER C N     1 
ATOM   5735  C CA    . SER C 1 345 ? 104.188 170.775 156.370 1.00 57.90  ? 316 SER C CA    1 
ATOM   5736  C C     . SER C 1 345 ? 105.099 171.019 155.176 1.00 57.90  ? 316 SER C C     1 
ATOM   5737  O O     . SER C 1 345 ? 105.433 172.173 154.862 1.00 57.90  ? 316 SER C O     1 
ATOM   5738  C CB    . SER C 1 345 ? 105.015 170.417 157.601 1.00 57.90  ? 316 SER C CB    1 
ATOM   5739  O OG    . SER C 1 345 ? 105.732 169.214 157.397 1.00 57.90  ? 316 SER C OG    1 
ATOM   5740  N N     . TYR C 1 346 ? 105.507 169.946 154.490 1.00 55.71  ? 317 TYR C N     1 
ATOM   5741  C CA    . TYR C 1 346 ? 106.409 170.133 153.366 1.00 55.71  ? 317 TYR C CA    1 
ATOM   5742  C C     . TYR C 1 346 ? 105.674 170.812 152.219 1.00 55.71  ? 317 TYR C C     1 
ATOM   5743  O O     . TYR C 1 346 ? 106.259 171.635 151.512 1.00 55.71  ? 317 TYR C O     1 
ATOM   5744  C CB    . TYR C 1 346 ? 107.081 168.794 152.994 1.00 55.71  ? 317 TYR C CB    1 
ATOM   5745  C CG    . TYR C 1 346 ? 107.833 168.699 151.659 1.00 55.71  ? 317 TYR C CG    1 
ATOM   5746  C CD1   . TYR C 1 346 ? 107.199 168.616 150.412 1.00 55.71  ? 317 TYR C CD1   1 
ATOM   5747  C CD2   . TYR C 1 346 ? 109.214 168.838 151.662 1.00 55.71  ? 317 TYR C CD2   1 
ATOM   5748  C CE1   . TYR C 1 346 ? 107.922 168.578 149.252 1.00 55.71  ? 317 TYR C CE1   1 
ATOM   5749  C CE2   . TYR C 1 346 ? 109.938 168.826 150.503 1.00 55.71  ? 317 TYR C CE2   1 
ATOM   5750  C CZ    . TYR C 1 346 ? 109.292 168.682 149.307 1.00 55.71  ? 317 TYR C CZ    1 
ATOM   5751  O OH    . TYR C 1 346 ? 110.026 168.657 148.151 1.00 55.71  ? 317 TYR C OH    1 
ATOM   5752  N N     . LEU C 1 347 ? 104.394 170.486 152.016 1.00 50.27  ? 318 LEU C N     1 
ATOM   5753  C CA    . LEU C 1 347 ? 103.619 171.201 151.005 1.00 50.27  ? 318 LEU C CA    1 
ATOM   5754  C C     . LEU C 1 347 ? 103.442 172.665 151.385 1.00 50.27  ? 318 LEU C C     1 
ATOM   5755  O O     . LEU C 1 347 ? 103.460 173.542 150.513 1.00 50.27  ? 318 LEU C O     1 
ATOM   5756  C CB    . LEU C 1 347 ? 102.255 170.536 150.799 1.00 50.27  ? 318 LEU C CB    1 
ATOM   5757  C CG    . LEU C 1 347 ? 102.158 169.413 149.759 1.00 50.27  ? 318 LEU C CG    1 
ATOM   5758  C CD1   . LEU C 1 347 ? 100.809 168.722 149.865 1.00 50.27  ? 318 LEU C CD1   1 
ATOM   5759  C CD2   . LEU C 1 347 ? 102.370 169.932 148.337 1.00 50.27  ? 318 LEU C CD2   1 
ATOM   5760  N N     . ASN C 1 348 ? 103.280 172.944 152.684 1.00 49.31  ? 319 ASN C N     1 
ATOM   5761  C CA    . ASN C 1 348 ? 103.119 174.321 153.139 1.00 49.31  ? 319 ASN C CA    1 
ATOM   5762  C C     . ASN C 1 348 ? 104.352 175.162 152.832 1.00 49.31  ? 319 ASN C C     1 
ATOM   5763  O O     . ASN C 1 348 ? 104.232 176.288 152.335 1.00 49.31  ? 319 ASN C O     1 
ATOM   5764  C CB    . ASN C 1 348 ? 102.823 174.343 154.639 1.00 49.31  ? 319 ASN C CB    1 
ATOM   5765  C CG    . ASN C 1 348 ? 102.251 175.671 155.111 1.00 49.31  ? 319 ASN C CG    1 
ATOM   5766  O OD1   . ASN C 1 348 ? 101.794 176.493 154.316 1.00 49.31  ? 319 ASN C OD1   1 
ATOM   5767  N ND2   . ASN C 1 348 ? 102.279 175.886 156.419 1.00 49.31  ? 319 ASN C ND2   1 
ATOM   5768  N N     . ARG C 1 349 ? 105.547 174.632 153.111 1.00 54.64  ? 320 ARG C N     1 
ATOM   5769  C CA    . ARG C 1 349 ? 106.757 175.372 152.738 1.00 54.64  ? 320 ARG C CA    1 
ATOM   5770  C C     . ARG C 1 349 ? 106.998 175.363 151.229 1.00 54.64  ? 320 ARG C C     1 
ATOM   5771  O O     . ARG C 1 349 ? 107.508 176.349 150.686 1.00 54.64  ? 320 ARG C O     1 
ATOM   5772  C CB    . ARG C 1 349 ? 107.993 174.841 153.476 1.00 54.64  ? 320 ARG C CB    1 
ATOM   5773  C CG    . ARG C 1 349 ? 108.289 173.377 153.281 1.00 54.64  ? 320 ARG C CG    1 
ATOM   5774  C CD    . ARG C 1 349 ? 109.615 172.946 153.884 1.00 54.64  ? 320 ARG C CD    1 
ATOM   5775  N NE    . ARG C 1 349 ? 110.693 173.057 152.898 1.00 54.64  ? 320 ARG C NE    1 
ATOM   5776  C CZ    . ARG C 1 349 ? 111.557 172.110 152.534 1.00 54.64  ? 320 ARG C CZ    1 
ATOM   5777  N NH1   . ARG C 1 349 ? 111.557 170.896 153.071 1.00 54.64  ? 320 ARG C NH1   1 
ATOM   5778  N NH2   . ARG C 1 349 ? 112.455 172.388 151.594 1.00 54.64  ? 320 ARG C NH2   1 
ATOM   5779  N N     . ALA C 1 350 ? 106.642 174.279 150.534 1.00 51.65  ? 321 ALA C N     1 
ATOM   5780  C CA    . ALA C 1 350 ? 106.939 174.173 149.110 1.00 51.65  ? 321 ALA C CA    1 
ATOM   5781  C C     . ALA C 1 350 ? 106.027 175.038 148.252 1.00 51.65  ? 321 ALA C C     1 
ATOM   5782  O O     . ALA C 1 350 ? 106.388 175.349 147.113 1.00 51.65  ? 321 ALA C O     1 
ATOM   5783  C CB    . ALA C 1 350 ? 106.833 172.716 148.662 1.00 51.65  ? 321 ALA C CB    1 
ATOM   5784  N N     . LEU C 1 351 ? 104.856 175.428 148.761 1.00 47.52  ? 322 LEU C N     1 
ATOM   5785  C CA    . LEU C 1 351 ? 104.013 176.372 148.034 1.00 47.52  ? 322 LEU C CA    1 
ATOM   5786  C C     . LEU C 1 351 ? 104.636 177.764 147.932 1.00 47.52  ? 322 LEU C C     1 
ATOM   5787  O O     . LEU C 1 351 ? 104.221 178.547 147.072 1.00 47.52  ? 322 LEU C O     1 
ATOM   5788  C CB    . LEU C 1 351 ? 102.640 176.471 148.702 1.00 47.52  ? 322 LEU C CB    1 
ATOM   5789  C CG    . LEU C 1 351 ? 101.662 175.320 148.440 1.00 47.52  ? 322 LEU C CG    1 
ATOM   5790  C CD1   . LEU C 1 351 ? 100.535 175.342 149.461 1.00 47.52  ? 322 LEU C CD1   1 
ATOM   5791  C CD2   . LEU C 1 351 ? 101.098 175.375 147.025 1.00 47.52  ? 322 LEU C CD2   1 
ATOM   5792  N N     . GLU C 1 352 ? 105.614 178.092 148.783 1.00 53.70  ? 323 GLU C N     1 
ATOM   5793  C CA    . GLU C 1 352 ? 106.268 179.395 148.730 1.00 53.70  ? 323 GLU C CA    1 
ATOM   5794  C C     . GLU C 1 352 ? 107.059 179.620 147.447 1.00 53.70  ? 323 GLU C C     1 
ATOM   5795  O O     . GLU C 1 352 ? 107.304 180.778 147.091 1.00 53.70  ? 323 GLU C O     1 
ATOM   5796  C CB    . GLU C 1 352 ? 107.211 179.556 149.927 1.00 53.70  ? 323 GLU C CB    1 
ATOM   5797  C CG    . GLU C 1 352 ? 106.536 179.543 151.295 1.00 53.70  ? 323 GLU C CG    1 
ATOM   5798  C CD    . GLU C 1 352 ? 105.654 180.753 151.528 1.00 53.70  ? 323 GLU C CD    1 
ATOM   5799  O OE1   . GLU C 1 352 ? 106.067 181.874 151.164 1.00 53.70  ? 323 GLU C OE1   1 
ATOM   5800  O OE2   . GLU C 1 352 ? 104.541 180.582 152.069 1.00 53.70  ? 323 GLU C OE2   1 
ATOM   5801  N N     . SER C 1 353 ? 107.479 178.558 146.759 1.00 56.45  ? 324 SER C N     1 
ATOM   5802  C CA    . SER C 1 353 ? 108.310 178.713 145.571 1.00 56.45  ? 324 SER C CA    1 
ATOM   5803  C C     . SER C 1 353 ? 107.538 179.402 144.452 1.00 56.45  ? 324 SER C C     1 
ATOM   5804  O O     . SER C 1 353 ? 106.347 179.152 144.248 1.00 56.45  ? 324 SER C O     1 
ATOM   5805  C CB    . SER C 1 353 ? 108.815 177.352 145.095 1.00 56.45  ? 324 SER C CB    1 
ATOM   5806  O OG    . SER C 1 353 ? 107.750 176.551 144.618 1.00 56.45  ? 324 SER C OG    1 
ATOM   5807  N N     . SER C 1 354 ? 108.232 180.282 143.727 1.00 58.70  ? 325 SER C N     1 
ATOM   5808  C CA    . SER C 1 354 ? 107.579 181.076 142.691 1.00 58.70  ? 325 SER C CA    1 
ATOM   5809  C C     . SER C 1 354 ? 107.123 180.221 141.515 1.00 58.70  ? 325 SER C C     1 
ATOM   5810  O O     . SER C 1 354 ? 106.119 180.545 140.872 1.00 58.70  ? 325 SER C O     1 
ATOM   5811  C CB    . SER C 1 354 ? 108.524 182.175 142.208 1.00 58.70  ? 325 SER C CB    1 
ATOM   5812  O OG    . SER C 1 354 ? 109.783 181.638 141.841 1.00 58.70  ? 325 SER C OG    1 
ATOM   5813  N N     . LEU C 1 355 ? 107.836 179.135 141.220 1.00 63.96  ? 326 LEU C N     1 
ATOM   5814  C CA    . LEU C 1 355 ? 107.518 178.289 140.076 1.00 63.96  ? 326 LEU C CA    1 
ATOM   5815  C C     . LEU C 1 355 ? 106.381 177.306 140.340 1.00 63.96  ? 326 LEU C C     1 
ATOM   5816  O O     . LEU C 1 355 ? 106.042 176.540 139.434 1.00 63.96  ? 326 LEU C O     1 
ATOM   5817  C CB    . LEU C 1 355 ? 108.760 177.500 139.646 1.00 63.96  ? 326 LEU C CB    1 
ATOM   5818  C CG    . LEU C 1 355 ? 110.041 178.273 139.322 1.00 63.96  ? 326 LEU C CG    1 
ATOM   5819  C CD1   . LEU C 1 355 ? 111.179 177.298 139.079 1.00 63.96  ? 326 LEU C CD1   1 
ATOM   5820  C CD2   . LEU C 1 355 ? 109.871 179.181 138.117 1.00 63.96  ? 326 LEU C CD2   1 
ATOM   5821  N N     . SER C 1 356 ? 105.780 177.307 141.531 1.00 53.35  ? 327 SER C N     1 
ATOM   5822  C CA    . SER C 1 356 ? 104.870 176.240 141.909 1.00 53.35  ? 327 SER C CA    1 
ATOM   5823  C C     . SER C 1 356 ? 103.565 176.312 141.109 1.00 53.35  ? 327 SER C C     1 
ATOM   5824  O O     . SER C 1 356 ? 103.185 177.384 140.631 1.00 53.35  ? 327 SER C O     1 
ATOM   5825  C CB    . SER C 1 356 ? 104.554 176.316 143.399 1.00 53.35  ? 327 SER C CB    1 
ATOM   5826  O OG    . SER C 1 356 ? 104.172 177.627 143.778 1.00 53.35  ? 327 SER C OG    1 
ATOM   5827  N N     . PRO C 1 357 ? 102.845 175.161 140.945 1.00 46.98  ? 328 PRO C N     1 
ATOM   5828  C CA    . PRO C 1 357 ? 101.535 175.199 140.286 1.00 46.98  ? 328 PRO C CA    1 
ATOM   5829  C C     . PRO C 1 357 ? 100.406 175.377 141.286 1.00 46.98  ? 328 PRO C C     1 
ATOM   5830  O O     . PRO C 1 357 ? 100.642 175.378 142.498 1.00 46.98  ? 328 PRO C O     1 
ATOM   5831  C CB    . PRO C 1 357 ? 101.467 173.831 139.609 1.00 46.98  ? 328 PRO C CB    1 
ATOM   5832  C CG    . PRO C 1 357 ? 102.115 172.947 140.604 1.00 46.98  ? 328 PRO C CG    1 
ATOM   5833  C CD    . PRO C 1 357 ? 103.204 173.766 141.266 1.00 46.98  ? 328 PRO C CD    1 
ATOM   5834  N N     . ILE C 1 358 ? 99.178  175.517 140.792 1.00 36.07  ? 329 ILE C N     1 
ATOM   5835  C CA    . ILE C 1 358 ? 98.017  175.486 141.682 1.00 36.07  ? 329 ILE C CA    1 
ATOM   5836  C C     . ILE C 1 358 ? 97.824  174.055 142.175 1.00 36.07  ? 329 ILE C C     1 
ATOM   5837  O O     . ILE C 1 358 ? 97.711  173.113 141.380 1.00 36.07  ? 329 ILE C O     1 
ATOM   5838  C CB    . ILE C 1 358 ? 96.742  176.041 141.008 1.00 36.07  ? 329 ILE C CB    1 
ATOM   5839  C CG1   . ILE C 1 358 ? 95.510  175.756 141.881 1.00 36.07  ? 329 ILE C CG1   1 
ATOM   5840  C CG2   . ILE C 1 358 ? 96.493  175.486 139.597 1.00 36.07  ? 329 ILE C CG2   1 
ATOM   5841  C CD1   . ILE C 1 358 ? 94.340  176.656 141.633 1.00 36.07  ? 329 ILE C CD1   1 
ATOM   5842  N N     . VAL C 1 359 ? 97.806  173.894 143.497 1.00 33.88  ? 330 VAL C N     1 
ATOM   5843  C CA    . VAL C 1 359 ? 97.513  172.628 144.158 1.00 33.88  ? 330 VAL C CA    1 
ATOM   5844  C C     . VAL C 1 359 ? 96.045  172.655 144.557 1.00 33.88  ? 330 VAL C C     1 
ATOM   5845  O O     . VAL C 1 359 ? 95.615  173.552 145.296 1.00 33.88  ? 330 VAL C O     1 
ATOM   5846  C CB    . VAL C 1 359 ? 98.420  172.410 145.380 1.00 33.88  ? 330 VAL C CB    1 
ATOM   5847  C CG1   . VAL C 1 359 ? 98.125  171.054 146.047 1.00 33.88  ? 330 VAL C CG1   1 
ATOM   5848  C CG2   . VAL C 1 359 ? 99.886  172.526 144.967 1.00 33.88  ? 330 VAL C CG2   1 
ATOM   5849  N N     . ILE C 1 360 ? 95.290  171.671 144.069 1.00 31.35  ? 331 ILE C N     1 
ATOM   5850  C CA    . ILE C 1 360 ? 93.868  171.507 144.354 1.00 31.35  ? 331 ILE C CA    1 
ATOM   5851  C C     . ILE C 1 360 ? 93.718  170.243 145.185 1.00 31.35  ? 331 ILE C C     1 
ATOM   5852  O O     . ILE C 1 360 ? 93.769  169.129 144.655 1.00 31.35  ? 331 ILE C O     1 
ATOM   5853  C CB    . ILE C 1 360 ? 93.018  171.428 143.074 1.00 31.35  ? 331 ILE C CB    1 
ATOM   5854  C CG1   . ILE C 1 360 ? 93.265  172.660 142.172 1.00 31.35  ? 331 ILE C CG1   1 
ATOM   5855  C CG2   . ILE C 1 360 ? 91.530  171.184 143.468 1.00 31.35  ? 331 ILE C CG2   1 
ATOM   5856  C CD1   . ILE C 1 360 ? 92.477  172.706 140.870 1.00 31.35  ? 331 ILE C CD1   1 
ATOM   5857  N N     . PHE C 1 361 ? 93.537  170.407 146.487 1.00 35.91  ? 332 PHE C N     1 
ATOM   5858  C CA    . PHE C 1 361 ? 93.182  169.291 147.342 1.00 35.91  ? 332 PHE C CA    1 
ATOM   5859  C C     . PHE C 1 361 ? 91.698  168.984 147.179 1.00 35.91  ? 332 PHE C C     1 
ATOM   5860  O O     . PHE C 1 361 ? 90.910  169.835 146.761 1.00 35.91  ? 332 PHE C O     1 
ATOM   5861  C CB    . PHE C 1 361 ? 93.499  169.616 148.800 1.00 35.91  ? 332 PHE C CB    1 
ATOM   5862  C CG    . PHE C 1 361 ? 94.916  170.057 149.032 1.00 35.91  ? 332 PHE C CG    1 
ATOM   5863  C CD1   . PHE C 1 361 ? 95.962  169.159 148.949 1.00 35.91  ? 332 PHE C CD1   1 
ATOM   5864  C CD2   . PHE C 1 361 ? 95.196  171.375 149.342 1.00 35.91  ? 332 PHE C CD2   1 
ATOM   5865  C CE1   . PHE C 1 361 ? 97.259  169.568 149.166 1.00 35.91  ? 332 PHE C CE1   1 
ATOM   5866  C CE2   . PHE C 1 361 ? 96.490  171.788 149.558 1.00 35.91  ? 332 PHE C CE2   1 
ATOM   5867  C CZ    . PHE C 1 361 ? 97.523  170.883 149.470 1.00 35.91  ? 332 PHE C CZ    1 
ATOM   5868  N N     . ALA C 1 362 ? 91.322  167.744 147.492 1.00 36.14  ? 333 ALA C N     1 
ATOM   5869  C CA    . ALA C 1 362 ? 89.922  167.333 147.497 1.00 36.14  ? 333 ALA C CA    1 
ATOM   5870  C C     . ALA C 1 362 ? 89.656  166.467 148.716 1.00 36.14  ? 333 ALA C C     1 
ATOM   5871  O O     . ALA C 1 362 ? 90.488  165.632 149.081 1.00 36.14  ? 333 ALA C O     1 
ATOM   5872  C CB    . ALA C 1 362 ? 89.551  166.575 146.221 1.00 36.14  ? 333 ALA C CB    1 
ATOM   5873  N N     . THR C 1 363 ? 88.496  166.673 149.341 1.00 40.77  ? 334 THR C N     1 
ATOM   5874  C CA    . THR C 1 363 ? 88.152  165.957 150.562 1.00 40.77  ? 334 THR C CA    1 
ATOM   5875  C C     . THR C 1 363 ? 86.644  165.781 150.663 1.00 40.77  ? 334 THR C C     1 
ATOM   5876  O O     . THR C 1 363 ? 85.862  166.536 150.075 1.00 40.77  ? 334 THR C O     1 
ATOM   5877  C CB    . THR C 1 363 ? 88.678  166.678 151.810 1.00 40.77  ? 334 THR C CB    1 
ATOM   5878  O OG1   . THR C 1 363 ? 88.542  165.819 152.949 1.00 40.77  ? 334 THR C OG1   1 
ATOM   5879  C CG2   . THR C 1 363 ? 87.919  167.977 152.066 1.00 40.77  ? 334 THR C CG2   1 
ATOM   5880  N N     . ASN C 1 364 ? 86.258  164.755 151.434 1.00 42.96  ? 335 ASN C N     1 
ATOM   5881  C CA    . ASN C 1 364 ? 84.859  164.429 151.686 1.00 42.96  ? 335 ASN C CA    1 
ATOM   5882  C C     . ASN C 1 364 ? 84.588  164.027 153.134 1.00 42.96  ? 335 ASN C C     1 
ATOM   5883  O O     . ASN C 1 364 ? 83.472  163.581 153.428 1.00 42.96  ? 335 ASN C O     1 
ATOM   5884  C CB    . ASN C 1 364 ? 84.408  163.298 150.750 1.00 42.96  ? 335 ASN C CB    1 
ATOM   5885  C CG    . ASN C 1 364 ? 85.148  161.995 150.997 1.00 42.96  ? 335 ASN C CG    1 
ATOM   5886  O OD1   . ASN C 1 364 ? 84.885  161.289 151.969 1.00 42.96  ? 335 ASN C OD1   1 
ATOM   5887  N ND2   . ASN C 1 364 ? 86.079  161.668 150.107 1.00 42.96  ? 335 ASN C ND2   1 
ATOM   5888  N N     . ARG C 1 365 ? 85.555  164.179 154.046 1.00 51.95  ? 336 ARG C N     1 
ATOM   5889  C CA    . ARG C 1 365 ? 85.450  163.645 155.403 1.00 51.95  ? 336 ARG C CA    1 
ATOM   5890  C C     . ARG C 1 365 ? 84.921  164.678 156.396 1.00 51.95  ? 336 ARG C C     1 
ATOM   5891  O O     . ARG C 1 365 ? 83.879  164.462 157.022 1.00 51.95  ? 336 ARG C O     1 
ATOM   5892  C CB    . ARG C 1 365 ? 86.820  163.121 155.860 1.00 51.95  ? 336 ARG C CB    1 
ATOM   5893  C CG    . ARG C 1 365 ? 87.377  161.955 155.033 1.00 51.95  ? 336 ARG C CG    1 
ATOM   5894  C CD    . ARG C 1 365 ? 86.526  160.692 155.162 1.00 51.95  ? 336 ARG C CD    1 
ATOM   5895  N NE    . ARG C 1 365 ? 87.263  159.472 154.838 1.00 51.95  ? 336 ARG C NE    1 
ATOM   5896  C CZ    . ARG C 1 365 ? 87.377  158.924 153.631 1.00 51.95  ? 336 ARG C CZ    1 
ATOM   5897  N NH1   . ARG C 1 365 ? 86.848  159.480 152.548 1.00 51.95  ? 336 ARG C NH1   1 
ATOM   5898  N NH2   . ARG C 1 365 ? 88.049  157.783 153.502 1.00 51.95  ? 336 ARG C NH2   1 
ATOM   5899  N N     . GLY C 1 366 ? 85.628  165.797 156.547 1.00 53.14  ? 337 GLY C N     1 
ATOM   5900  C CA    . GLY C 1 366 ? 85.311  166.786 157.564 1.00 53.14  ? 337 GLY C CA    1 
ATOM   5901  C C     . GLY C 1 366 ? 86.128  166.581 158.824 1.00 53.14  ? 337 GLY C C     1 
ATOM   5902  O O     . GLY C 1 366 ? 87.322  166.891 158.843 1.00 53.14  ? 337 GLY C O     1 
ATOM   5903  N N     . VAL C 1 367 ? 85.508  166.063 159.883 1.00 60.64  ? 338 VAL C N     1 
ATOM   5904  C CA    . VAL C 1 367 ? 86.247  165.747 161.102 1.00 60.64  ? 338 VAL C CA    1 
ATOM   5905  C C     . VAL C 1 367 ? 87.170  164.573 160.807 1.00 60.64  ? 338 VAL C C     1 
ATOM   5906  O O     . VAL C 1 367 ? 86.718  163.495 160.403 1.00 60.64  ? 338 VAL C O     1 
ATOM   5907  C CB    . VAL C 1 367 ? 85.291  165.432 162.265 1.00 60.64  ? 338 VAL C CB    1 
ATOM   5908  C CG1   . VAL C 1 367 ? 86.031  164.768 163.444 1.00 60.64  ? 338 VAL C CG1   1 
ATOM   5909  C CG2   . VAL C 1 367 ? 84.585  166.693 162.740 1.00 60.64  ? 338 VAL C CG2   1 
ATOM   5910  N N     . CYS C 1 368 ? 88.469  164.778 161.010 1.00 60.97  ? 339 CYS C N     1 
ATOM   5911  C CA    . CYS C 1 368 ? 89.439  163.712 160.803 1.00 60.97  ? 339 CYS C CA    1 
ATOM   5912  C C     . CYS C 1 368 ? 90.752  164.117 161.449 1.00 60.97  ? 339 CYS C C     1 
ATOM   5913  O O     . CYS C 1 368 ? 91.255  165.214 161.191 1.00 60.97  ? 339 CYS C O     1 
ATOM   5914  C CB    . CYS C 1 368 ? 89.635  163.431 159.311 1.00 60.97  ? 339 CYS C CB    1 
ATOM   5915  S SG    . CYS C 1 368 ? 90.951  162.254 158.947 1.00 60.97  ? 339 CYS C SG    1 
ATOM   5916  N N     . ASN C 1 369 ? 91.293  163.238 162.290 1.00 68.46  ? 340 ASN C N     1 
ATOM   5917  C CA    . ASN C 1 369 ? 92.585  163.493 162.909 1.00 68.46  ? 340 ASN C CA    1 
ATOM   5918  C C     . ASN C 1 369 ? 93.673  163.540 161.848 1.00 68.46  ? 340 ASN C C     1 
ATOM   5919  O O     . ASN C 1 369 ? 93.650  162.779 160.878 1.00 68.46  ? 340 ASN C O     1 
ATOM   5920  C CB    . ASN C 1 369 ? 92.901  162.413 163.942 1.00 68.46  ? 340 ASN C CB    1 
ATOM   5921  C CG    . ASN C 1 369 ? 91.914  162.398 165.091 1.00 68.46  ? 340 ASN C CG    1 
ATOM   5922  O OD1   . ASN C 1 369 ? 91.078  163.291 165.217 1.00 68.46  ? 340 ASN C OD1   1 
ATOM   5923  N ND2   . ASN C 1 369 ? 92.009  161.380 165.938 1.00 68.46  ? 340 ASN C ND2   1 
ATOM   5924  N N     . VAL C 1 370 ? 94.639  164.436 162.041 1.00 63.72  ? 341 VAL C N     1 
ATOM   5925  C CA    . VAL C 1 370 ? 95.714  164.574 161.065 1.00 63.72  ? 341 VAL C CA    1 
ATOM   5926  C C     . VAL C 1 370 ? 96.601  163.343 161.165 1.00 63.72  ? 341 VAL C C     1 
ATOM   5927  O O     . VAL C 1 370 ? 97.030  162.957 162.260 1.00 63.72  ? 341 VAL C O     1 
ATOM   5928  C CB    . VAL C 1 370 ? 96.518  165.871 161.277 1.00 63.72  ? 341 VAL C CB    1 
ATOM   5929  C CG1   . VAL C 1 370 ? 97.353  166.197 160.031 1.00 63.72  ? 341 VAL C CG1   1 
ATOM   5930  C CG2   . VAL C 1 370 ? 95.613  167.074 161.595 1.00 63.72  ? 341 VAL C CG2   1 
ATOM   5931  N N     . ARG C 1 371 ? 96.852  162.709 160.022 1.00 63.72  ? 342 ARG C N     1 
ATOM   5932  C CA    . ARG C 1 371 ? 97.579  161.446 159.985 1.00 63.72  ? 342 ARG C CA    1 
ATOM   5933  C C     . ARG C 1 371 ? 99.006  161.647 160.483 1.00 63.72  ? 342 ARG C C     1 
ATOM   5934  O O     . ARG C 1 371 ? 99.718  162.542 160.020 1.00 63.72  ? 342 ARG C O     1 
ATOM   5935  C CB    . ARG C 1 371 ? 97.544  160.899 158.552 1.00 63.72  ? 342 ARG C CB    1 
ATOM   5936  C CG    . ARG C 1 371 ? 98.490  159.756 158.166 1.00 63.72  ? 342 ARG C CG    1 
ATOM   5937  C CD    . ARG C 1 371 ? 98.180  158.459 158.878 1.00 63.72  ? 342 ARG C CD    1 
ATOM   5938  N NE    . ARG C 1 371 ? 98.645  157.322 158.091 1.00 63.72  ? 342 ARG C NE    1 
ATOM   5939  C CZ    . ARG C 1 371 ? 99.916  156.985 157.898 1.00 63.72  ? 342 ARG C CZ    1 
ATOM   5940  N NH1   . ARG C 1 371 ? 100.916 157.664 158.443 1.00 63.72  ? 342 ARG C NH1   1 
ATOM   5941  N NH2   . ARG C 1 371 ? 100.194 155.936 157.129 1.00 63.72  ? 342 ARG C NH2   1 
ATOM   5942  N N     . GLY C 1 372 ? 99.410  160.809 161.442 1.00 69.12  ? 343 GLY C N     1 
ATOM   5943  C CA    . GLY C 1 372 ? 100.680 160.931 162.128 1.00 69.12  ? 343 GLY C CA    1 
ATOM   5944  C C     . GLY C 1 372 ? 100.625 161.641 163.467 1.00 69.12  ? 343 GLY C C     1 
ATOM   5945  O O     . GLY C 1 372 ? 101.623 161.610 164.199 1.00 69.12  ? 343 GLY C O     1 
ATOM   5946  N N     . THR C 1 373 ? 99.505  162.292 163.802 1.00 74.48  ? 344 THR C N     1 
ATOM   5947  C CA    . THR C 1 373 ? 99.308  162.944 165.093 1.00 74.48  ? 344 THR C CA    1 
ATOM   5948  C C     . THR C 1 373 ? 97.893  162.660 165.576 1.00 74.48  ? 344 THR C C     1 
ATOM   5949  O O     . THR C 1 373 ? 97.052  162.142 164.837 1.00 74.48  ? 344 THR C O     1 
ATOM   5950  C CB    . THR C 1 373 ? 99.538  164.462 165.019 1.00 74.48  ? 344 THR C CB    1 
ATOM   5951  O OG1   . THR C 1 373 ? 98.500  165.069 164.241 1.00 74.48  ? 344 THR C OG1   1 
ATOM   5952  C CG2   . THR C 1 373 ? 100.894 164.786 164.406 1.00 74.48  ? 344 THR C CG2   1 
ATOM   5953  N N     . ASP C 1 374 ? 97.640  163.003 166.841 1.00 84.67  ? 345 ASP C N     1 
ATOM   5954  C CA    . ASP C 1 374 ? 96.358  162.760 167.494 1.00 84.67  ? 345 ASP C CA    1 
ATOM   5955  C C     . ASP C 1 374 ? 95.420  163.965 167.495 1.00 84.67  ? 345 ASP C C     1 
ATOM   5956  O O     . ASP C 1 374 ? 94.275  163.828 167.935 1.00 84.67  ? 345 ASP C O     1 
ATOM   5957  C CB    . ASP C 1 374 ? 96.592  162.314 168.943 1.00 84.67  ? 345 ASP C CB    1 
ATOM   5958  C CG    . ASP C 1 374 ? 97.579  161.167 169.047 1.00 84.67  ? 345 ASP C CG    1 
ATOM   5959  O OD1   . ASP C 1 374 ? 97.889  160.549 168.006 1.00 84.67  ? 345 ASP C OD1   1 
ATOM   5960  O OD2   . ASP C 1 374 ? 98.046  160.884 170.170 1.00 84.67  ? 345 ASP C OD2   1 
ATOM   5961  N N     . MET C 1 375 ? 95.860  165.131 167.020 1.00 76.48  ? 346 MET C N     1 
ATOM   5962  C CA    . MET C 1 375 ? 95.040  166.336 167.138 1.00 76.48  ? 346 MET C CA    1 
ATOM   5963  C C     . MET C 1 375 ? 93.942  166.333 166.069 1.00 76.48  ? 346 MET C C     1 
ATOM   5964  O O     . MET C 1 375 ? 94.248  166.144 164.888 1.00 76.48  ? 346 MET C O     1 
ATOM   5965  C CB    . MET C 1 375 ? 95.899  167.601 167.007 1.00 76.48  ? 346 MET C CB    1 
ATOM   5966  C CG    . MET C 1 375 ? 96.700  167.766 165.710 1.00 76.48  ? 346 MET C CG    1 
ATOM   5967  S SD    . MET C 1 375 ? 97.730  169.244 165.751 1.00 76.48  ? 346 MET C SD    1 
ATOM   5968  C CE    . MET C 1 375 ? 99.272  168.567 166.359 1.00 76.48  ? 346 MET C CE    1 
ATOM   5969  N N     . PRO C 1 376 ? 92.662  166.512 166.424 1.00 70.98  ? 347 PRO C N     1 
ATOM   5970  C CA    . PRO C 1 376 ? 91.660  166.739 165.375 1.00 70.98  ? 347 PRO C CA    1 
ATOM   5971  C C     . PRO C 1 376 ? 91.868  168.072 164.676 1.00 70.98  ? 347 PRO C C     1 
ATOM   5972  O O     . PRO C 1 376 ? 92.413  169.021 165.246 1.00 70.98  ? 347 PRO C O     1 
ATOM   5973  C CB    . PRO C 1 376 ? 90.327  166.712 166.132 1.00 70.98  ? 347 PRO C CB    1 
ATOM   5974  C CG    . PRO C 1 376 ? 90.599  165.963 167.359 1.00 70.98  ? 347 PRO C CG    1 
ATOM   5975  C CD    . PRO C 1 376 ? 92.000  166.309 167.728 1.00 70.98  ? 347 PRO C CD    1 
ATOM   5976  N N     . SER C 1 377 ? 91.433  168.129 163.420 1.00 58.59  ? 348 SER C N     1 
ATOM   5977  C CA    . SER C 1 377 ? 91.481  169.354 162.635 1.00 58.59  ? 348 SER C CA    1 
ATOM   5978  C C     . SER C 1 377 ? 90.450  169.240 161.514 1.00 58.59  ? 348 SER C C     1 
ATOM   5979  O O     . SER C 1 377 ? 90.034  168.127 161.172 1.00 58.59  ? 348 SER C O     1 
ATOM   5980  C CB    . SER C 1 377 ? 92.889  169.590 162.066 1.00 58.59  ? 348 SER C CB    1 
ATOM   5981  O OG    . SER C 1 377 ? 93.837  169.817 163.089 1.00 58.59  ? 348 SER C OG    1 
ATOM   5982  N N     . PRO C 1 378 ? 90.000  170.362 160.934 1.00 49.34  ? 349 PRO C N     1 
ATOM   5983  C CA    . PRO C 1 378 ? 89.040  170.257 159.823 1.00 49.34  ? 349 PRO C CA    1 
ATOM   5984  C C     . PRO C 1 378 ? 89.668  169.625 158.589 1.00 49.34  ? 349 PRO C C     1 
ATOM   5985  O O     . PRO C 1 378 ? 90.766  169.998 158.171 1.00 49.34  ? 349 PRO C O     1 
ATOM   5986  C CB    . PRO C 1 378 ? 88.631  171.711 159.557 1.00 49.34  ? 349 PRO C CB    1 
ATOM   5987  C CG    . PRO C 1 378 ? 88.957  172.438 160.775 1.00 49.34  ? 349 PRO C CG    1 
ATOM   5988  C CD    . PRO C 1 378 ? 90.155  171.770 161.354 1.00 49.34  ? 349 PRO C CD    1 
ATOM   5989  N N     . HIS C 1 379 ? 88.956  168.656 158.010 1.00 46.39  ? 350 HIS C N     1 
ATOM   5990  C CA    . HIS C 1 379 ? 89.327  167.999 156.756 1.00 46.39  ? 350 HIS C CA    1 
ATOM   5991  C C     . HIS C 1 379 ? 90.661  167.259 156.832 1.00 46.39  ? 350 HIS C C     1 
ATOM   5992  O O     . HIS C 1 379 ? 91.272  166.981 155.797 1.00 46.39  ? 350 HIS C O     1 
ATOM   5993  C CB    . HIS C 1 379 ? 89.367  169.007 155.603 1.00 46.39  ? 350 HIS C CB    1 
ATOM   5994  C CG    . HIS C 1 379 ? 88.157  169.883 155.522 1.00 46.39  ? 350 HIS C CG    1 
ATOM   5995  N ND1   . HIS C 1 379 ? 86.896  169.389 155.265 1.00 46.39  ? 350 HIS C ND1   1 
ATOM   5996  C CD2   . HIS C 1 379 ? 88.016  171.223 155.650 1.00 46.39  ? 350 HIS C CD2   1 
ATOM   5997  C CE1   . HIS C 1 379 ? 86.031  170.386 155.248 1.00 46.39  ? 350 HIS C CE1   1 
ATOM   5998  N NE2   . HIS C 1 379 ? 86.685  171.510 155.477 1.00 46.39  ? 350 HIS C NE2   1 
ATOM   5999  N N     . GLY C 1 380 ? 91.136  166.920 158.029 1.00 53.16  ? 351 GLY C N     1 
ATOM   6000  C CA    . GLY C 1 380 ? 92.410  166.239 158.155 1.00 53.16  ? 351 GLY C CA    1 
ATOM   6001  C C     . GLY C 1 380 ? 93.625  167.046 157.752 1.00 53.16  ? 351 GLY C C     1 
ATOM   6002  O O     . GLY C 1 380 ? 94.692  166.460 157.550 1.00 53.16  ? 351 GLY C O     1 
ATOM   6003  N N     . VAL C 1 381 ? 93.498  168.369 157.641 1.00 47.53  ? 352 VAL C N     1 
ATOM   6004  C CA    . VAL C 1 381 ? 94.569  169.274 157.220 1.00 47.53  ? 352 VAL C CA    1 
ATOM   6005  C C     . VAL C 1 381 ? 95.004  170.052 158.462 1.00 47.53  ? 352 VAL C C     1 
ATOM   6006  O O     . VAL C 1 381 ? 94.136  170.416 159.266 1.00 47.53  ? 352 VAL C O     1 
ATOM   6007  C CB    . VAL C 1 381 ? 94.090  170.215 156.099 1.00 47.53  ? 352 VAL C CB    1 
ATOM   6008  C CG1   . VAL C 1 381 ? 95.257  170.986 155.490 1.00 47.53  ? 352 VAL C CG1   1 
ATOM   6009  C CG2   . VAL C 1 381 ? 93.348  169.430 155.016 1.00 47.53  ? 352 VAL C CG2   1 
ATOM   6010  N N     . PRO C 1 382 ? 96.290  170.345 158.686 1.00 51.66  ? 353 PRO C N     1 
ATOM   6011  C CA    . PRO C 1 382 ? 96.651  171.157 159.853 1.00 51.66  ? 353 PRO C CA    1 
ATOM   6012  C C     . PRO C 1 382 ? 96.220  172.604 159.675 1.00 51.66  ? 353 PRO C C     1 
ATOM   6013  O O     . PRO C 1 382 ? 95.875  173.056 158.583 1.00 51.66  ? 353 PRO C O     1 
ATOM   6014  C CB    . PRO C 1 382 ? 98.174  171.032 159.921 1.00 51.66  ? 353 PRO C CB    1 
ATOM   6015  C CG    . PRO C 1 382 ? 98.576  170.788 158.536 1.00 51.66  ? 353 PRO C CG    1 
ATOM   6016  C CD    . PRO C 1 382 ? 97.509  169.904 157.979 1.00 51.66  ? 353 PRO C CD    1 
ATOM   6017  N N     . ILE C 1 383 ? 96.256  173.340 160.788 1.00 50.11  ? 354 ILE C N     1 
ATOM   6018  C CA    . ILE C 1 383 ? 95.844  174.741 160.765 1.00 50.11  ? 354 ILE C CA    1 
ATOM   6019  C C     . ILE C 1 383 ? 96.822  175.571 159.942 1.00 50.11  ? 354 ILE C C     1 
ATOM   6020  O O     . ILE C 1 383 ? 96.424  176.517 159.247 1.00 50.11  ? 354 ILE C O     1 
ATOM   6021  C CB    . ILE C 1 383 ? 95.704  175.297 162.200 1.00 50.11  ? 354 ILE C CB    1 
ATOM   6022  C CG1   . ILE C 1 383 ? 94.831  174.392 163.100 1.00 50.11  ? 354 ILE C CG1   1 
ATOM   6023  C CG2   . ILE C 1 383 ? 95.163  176.737 162.159 1.00 50.11  ? 354 ILE C CG2   1 
ATOM   6024  C CD1   . ILE C 1 383 ? 93.459  174.032 162.542 1.00 50.11  ? 354 ILE C CD1   1 
ATOM   6025  N N     . ASP C 1 384 ? 98.114  175.230 160.003 1.00 50.22  ? 355 ASP C N     1 
ATOM   6026  C CA    . ASP C 1 384 ? 99.137  176.039 159.347 1.00 50.22  ? 355 ASP C CA    1 
ATOM   6027  C C     . ASP C 1 384 ? 99.003  176.018 157.828 1.00 50.22  ? 355 ASP C C     1 
ATOM   6028  O O     . ASP C 1 384 ? 99.413  176.982 157.170 1.00 50.22  ? 355 ASP C O     1 
ATOM   6029  C CB    . ASP C 1 384 ? 100.530 175.567 159.774 1.00 50.22  ? 355 ASP C CB    1 
ATOM   6030  C CG    . ASP C 1 384 ? 101.028 174.390 158.960 1.00 50.22  ? 355 ASP C CG    1 
ATOM   6031  O OD1   . ASP C 1 384 ? 100.276 173.405 158.817 1.00 50.22  ? 355 ASP C OD1   1 
ATOM   6032  O OD2   . ASP C 1 384 ? 102.172 174.449 158.462 1.00 50.22  ? 355 ASP C OD2   1 
ATOM   6033  N N     . LEU C 1 385 ? 98.436  174.945 157.259 1.00 46.81  ? 356 LEU C N     1 
ATOM   6034  C CA    . LEU C 1 385 ? 98.115  174.890 155.835 1.00 46.81  ? 356 LEU C CA    1 
ATOM   6035  C C     . LEU C 1 385 ? 96.692  175.341 155.551 1.00 46.81  ? 356 LEU C C     1 
ATOM   6036  O O     . LEU C 1 385 ? 96.438  175.903 154.483 1.00 46.81  ? 356 LEU C O     1 
ATOM   6037  C CB    . LEU C 1 385 ? 98.319  173.473 155.287 1.00 46.81  ? 356 LEU C CB    1 
ATOM   6038  C CG    . LEU C 1 385 ? 98.051  173.221 153.791 1.00 46.81  ? 356 LEU C CG    1 
ATOM   6039  C CD1   . LEU C 1 385 ? 98.841  174.150 152.872 1.00 46.81  ? 356 LEU C CD1   1 
ATOM   6040  C CD2   . LEU C 1 385 ? 98.358  171.779 153.460 1.00 46.81  ? 356 LEU C CD2   1 
ATOM   6041  N N     . LEU C 1 386 ? 95.758  175.135 156.486 1.00 47.37  ? 357 LEU C N     1 
ATOM   6042  C CA    . LEU C 1 386 ? 94.403  175.658 156.319 1.00 47.37  ? 357 LEU C CA    1 
ATOM   6043  C C     . LEU C 1 386 ? 94.353  177.181 156.313 1.00 47.37  ? 357 LEU C C     1 
ATOM   6044  O O     . LEU C 1 386 ? 93.345  177.746 155.876 1.00 47.37  ? 357 LEU C O     1 
ATOM   6045  C CB    . LEU C 1 386 ? 93.483  175.145 157.430 1.00 47.37  ? 357 LEU C CB    1 
ATOM   6046  C CG    . LEU C 1 386 ? 92.930  173.717 157.386 1.00 47.37  ? 357 LEU C CG    1 
ATOM   6047  C CD1   . LEU C 1 386 ? 92.128  173.436 158.648 1.00 47.37  ? 357 LEU C CD1   1 
ATOM   6048  C CD2   . LEU C 1 386 ? 92.069  173.477 156.155 1.00 47.37  ? 357 LEU C CD2   1 
ATOM   6049  N N     . ASP C 1 387 ? 95.392  177.852 156.823 1.00 49.16  ? 358 ASP C N     1 
ATOM   6050  C CA    . ASP C 1 387 ? 95.463  179.308 156.752 1.00 49.16  ? 358 ASP C CA    1 
ATOM   6051  C C     . ASP C 1 387 ? 95.390  179.826 155.317 1.00 49.16  ? 358 ASP C C     1 
ATOM   6052  O O     . ASP C 1 387 ? 94.804  180.890 155.083 1.00 49.16  ? 358 ASP C O     1 
ATOM   6053  C CB    . ASP C 1 387 ? 96.759  179.788 157.414 1.00 49.16  ? 358 ASP C CB    1 
ATOM   6054  C CG    . ASP C 1 387 ? 96.742  179.650 158.933 1.00 49.16  ? 358 ASP C CG    1 
ATOM   6055  O OD1   . ASP C 1 387 ? 95.651  179.576 159.538 1.00 49.16  ? 358 ASP C OD1   1 
ATOM   6056  O OD2   . ASP C 1 387 ? 97.839  179.618 159.528 1.00 49.16  ? 358 ASP C OD2   1 
ATOM   6057  N N     . ARG C 1 388 ? 95.949  179.086 154.351 1.00 45.48  ? 359 ARG C N     1 
ATOM   6058  C CA    . ARG C 1 388 ? 96.138  179.554 152.979 1.00 45.48  ? 359 ARG C CA    1 
ATOM   6059  C C     . ARG C 1 388 ? 95.305  178.785 151.951 1.00 45.48  ? 359 ARG C C     1 
ATOM   6060  O O     . ARG C 1 388 ? 95.676  178.758 150.773 1.00 45.48  ? 359 ARG C O     1 
ATOM   6061  C CB    . ARG C 1 388 ? 97.622  179.481 152.612 1.00 45.48  ? 359 ARG C CB    1 
ATOM   6062  C CG    . ARG C 1 388 ? 98.134  178.071 152.351 1.00 45.48  ? 359 ARG C CG    1 
ATOM   6063  C CD    . ARG C 1 388 ? 99.620  177.928 152.629 1.00 45.48  ? 359 ARG C CD    1 
ATOM   6064  N NE    . ARG C 1 388 ? 100.428 178.741 151.726 1.00 45.48  ? 359 ARG C NE    1 
ATOM   6065  C CZ    . ARG C 1 388 ? 101.718 179.018 151.882 1.00 45.48  ? 359 ARG C CZ    1 
ATOM   6066  N NH1   . ARG C 1 388 ? 102.413 178.580 152.923 1.00 45.48  ? 359 ARG C NH1   1 
ATOM   6067  N NH2   . ARG C 1 388 ? 102.332 179.758 150.963 1.00 45.48  ? 359 ARG C NH2   1 
ATOM   6068  N N     . LEU C 1 389 ? 94.181  178.188 152.358 1.00 40.38  ? 360 LEU C N     1 
ATOM   6069  C CA    . LEU C 1 389 ? 93.295  177.443 151.463 1.00 40.38  ? 360 LEU C CA    1 
ATOM   6070  C C     . LEU C 1 389 ? 92.063  178.271 151.125 1.00 40.38  ? 360 LEU C C     1 
ATOM   6071  O O     . LEU C 1 389 ? 91.458  178.882 152.013 1.00 40.38  ? 360 LEU C O     1 
ATOM   6072  C CB    . LEU C 1 389 ? 92.851  176.119 152.090 1.00 40.38  ? 360 LEU C CB    1 
ATOM   6073  C CG    . LEU C 1 389 ? 93.874  175.010 152.356 1.00 40.38  ? 360 LEU C CG    1 
ATOM   6074  C CD1   . LEU C 1 389 ? 93.168  173.757 152.834 1.00 40.38  ? 360 LEU C CD1   1 
ATOM   6075  C CD2   . LEU C 1 389 ? 94.733  174.682 151.141 1.00 40.38  ? 360 LEU C CD2   1 
ATOM   6076  N N     . VAL C 1 390 ? 91.700  178.281 149.844 1.00 37.48  ? 361 VAL C N     1 
ATOM   6077  C CA    . VAL C 1 390 ? 90.448  178.849 149.356 1.00 37.48  ? 361 VAL C CA    1 
ATOM   6078  C C     . VAL C 1 390 ? 89.520  177.674 149.081 1.00 37.48  ? 361 VAL C C     1 
ATOM   6079  O O     . VAL C 1 390 ? 89.781  176.867 148.183 1.00 37.48  ? 361 VAL C O     1 
ATOM   6080  C CB    . VAL C 1 390 ? 90.672  179.704 148.102 1.00 37.48  ? 361 VAL C CB    1 
ATOM   6081  C CG1   . VAL C 1 390 ? 89.367  180.378 147.648 1.00 37.48  ? 361 VAL C CG1   1 
ATOM   6082  C CG2   . VAL C 1 390 ? 91.765  180.731 148.370 1.00 37.48  ? 361 VAL C CG2   1 
ATOM   6083  N N     . ILE C 1 391 ? 88.430  177.586 149.838 1.00 36.67  ? 362 ILE C N     1 
ATOM   6084  C CA    . ILE C 1 391 ? 87.570  176.409 149.850 1.00 36.67  ? 362 ILE C CA    1 
ATOM   6085  C C     . ILE C 1 391 ? 86.456  176.671 148.846 1.00 36.67  ? 362 ILE C C     1 
ATOM   6086  O O     . ILE C 1 391 ? 86.032  177.814 148.648 1.00 36.67  ? 362 ILE C O     1 
ATOM   6087  C CB    . ILE C 1 391 ? 87.066  176.155 151.299 1.00 36.67  ? 362 ILE C CB    1 
ATOM   6088  C CG1   . ILE C 1 391 ? 88.184  175.455 152.104 1.00 36.67  ? 362 ILE C CG1   1 
ATOM   6089  C CG2   . ILE C 1 391 ? 85.765  175.242 151.397 1.00 36.67  ? 362 ILE C CG2   1 
ATOM   6090  C CD1   . ILE C 1 391 ? 87.809  174.839 153.451 1.00 36.67  ? 362 ILE C CD1   1 
ATOM   6091  N N     . ILE C 1 392 ? 85.990  175.602 148.196 1.00 31.80  ? 363 ILE C N     1 
ATOM   6092  C CA    . ILE C 1 392 ? 84.840  175.641 147.296 1.00 31.80  ? 363 ILE C CA    1 
ATOM   6093  C C     . ILE C 1 392 ? 83.954  174.447 147.622 1.00 31.80  ? 363 ILE C C     1 
ATOM   6094  O O     . ILE C 1 392 ? 84.450  173.333 147.825 1.00 31.80  ? 363 ILE C O     1 
ATOM   6095  C CB    . ILE C 1 392 ? 85.254  175.618 145.806 1.00 31.80  ? 363 ILE C CB    1 
ATOM   6096  C CG1   . ILE C 1 392 ? 86.058  176.876 145.438 1.00 31.80  ? 363 ILE C CG1   1 
ATOM   6097  C CG2   . ILE C 1 392 ? 84.000  175.484 144.913 1.00 31.80  ? 363 ILE C CG2   1 
ATOM   6098  C CD1   . ILE C 1 392 ? 86.760  176.822 144.089 1.00 31.80  ? 363 ILE C CD1   1 
ATOM   6099  N N     . ARG C 1 393 ? 82.644  174.682 147.669 1.00 39.59  ? 364 ARG C N     1 
ATOM   6100  C CA    . ARG C 1 393 ? 81.658  173.646 147.949 1.00 39.59  ? 364 ARG C CA    1 
ATOM   6101  C C     . ARG C 1 393 ? 81.169  173.019 146.650 1.00 39.59  ? 364 ARG C C     1 
ATOM   6102  O O     . ARG C 1 393 ? 81.050  173.698 145.627 1.00 39.59  ? 364 ARG C O     1 
ATOM   6103  C CB    . ARG C 1 393 ? 80.481  174.242 148.727 1.00 39.59  ? 364 ARG C CB    1 
ATOM   6104  C CG    . ARG C 1 393 ? 79.372  173.272 149.164 1.00 39.59  ? 364 ARG C CG    1 
ATOM   6105  C CD    . ARG C 1 393 ? 79.851  172.222 150.156 1.00 39.59  ? 364 ARG C CD    1 
ATOM   6106  N NE    . ARG C 1 393 ? 78.714  171.610 150.848 1.00 39.59  ? 364 ARG C NE    1 
ATOM   6107  C CZ    . ARG C 1 393 ? 78.535  170.318 151.116 1.00 39.59  ? 364 ARG C CZ    1 
ATOM   6108  N NH1   . ARG C 1 393 ? 79.444  169.399 150.824 1.00 39.59  ? 364 ARG C NH1   1 
ATOM   6109  N NH2   . ARG C 1 393 ? 77.410  169.934 151.710 1.00 39.59  ? 364 ARG C NH2   1 
ATOM   6110  N N     . THR C 1 394 ? 80.895  171.715 146.704 1.00 33.87  ? 365 THR C N     1 
ATOM   6111  C CA    . THR C 1 394 ? 80.256  170.975 145.622 1.00 33.87  ? 365 THR C CA    1 
ATOM   6112  C C     . THR C 1 394 ? 79.080  170.204 146.204 1.00 33.87  ? 365 THR C C     1 
ATOM   6113  O O     . THR C 1 394 ? 79.231  169.518 147.220 1.00 33.87  ? 365 THR C O     1 
ATOM   6114  C CB    . THR C 1 394 ? 81.240  170.024 144.934 1.00 33.87  ? 365 THR C CB    1 
ATOM   6115  O OG1   . THR C 1 394 ? 81.711  169.054 145.873 1.00 33.87  ? 365 THR C OG1   1 
ATOM   6116  C CG2   . THR C 1 394 ? 82.422  170.792 144.373 1.00 33.87  ? 365 THR C CG2   1 
ATOM   6117  N N     . GLN C 1 395 ? 77.924  170.307 145.550 1.00 35.02  ? 366 GLN C N     1 
ATOM   6118  C CA    . GLN C 1 395 ? 76.647  169.864 146.090 1.00 35.02  ? 366 GLN C CA    1 
ATOM   6119  C C     . GLN C 1 395 ? 76.160  168.607 145.380 1.00 35.02  ? 366 GLN C C     1 
ATOM   6120  O O     . GLN C 1 395 ? 76.415  168.406 144.190 1.00 35.02  ? 366 GLN C O     1 
ATOM   6121  C CB    . GLN C 1 395 ? 75.591  170.967 145.958 1.00 35.02  ? 366 GLN C CB    1 
ATOM   6122  C CG    . GLN C 1 395 ? 76.065  172.349 146.390 1.00 35.02  ? 366 GLN C CG    1 
ATOM   6123  C CD    . GLN C 1 395 ? 74.943  173.360 146.433 1.00 35.02  ? 366 GLN C CD    1 
ATOM   6124  O OE1   . GLN C 1 395 ? 74.589  173.866 147.497 1.00 35.02  ? 366 GLN C OE1   1 
ATOM   6125  N NE2   . GLN C 1 395 ? 74.378  173.666 145.272 1.00 35.02  ? 366 GLN C NE2   1 
ATOM   6126  N N     . ILE C 1 396 ? 75.442  167.767 146.129 1.00 35.63  ? 367 ILE C N     1 
ATOM   6127  C CA    . ILE C 1 396 ? 74.916  166.520 145.588 1.00 35.63  ? 367 ILE C CA    1 
ATOM   6128  C C     . ILE C 1 396 ? 73.844  166.816 144.543 1.00 35.63  ? 367 ILE C C     1 
ATOM   6129  O O     . ILE C 1 396 ? 73.209  167.879 144.552 1.00 35.63  ? 367 ILE C O     1 
ATOM   6130  C CB    . ILE C 1 396 ? 74.365  165.644 146.733 1.00 35.63  ? 367 ILE C CB    1 
ATOM   6131  C CG1   . ILE C 1 396 ? 74.158  164.165 146.338 1.00 35.63  ? 367 ILE C CG1   1 
ATOM   6132  C CG2   . ILE C 1 396 ? 73.048  166.213 147.277 1.00 35.63  ? 367 ILE C CG2   1 
ATOM   6133  C CD1   . ILE C 1 396 ? 75.372  163.416 145.790 1.00 35.63  ? 367 ILE C CD1   1 
ATOM   6134  N N     . TYR C 1 397 ? 73.637  165.861 143.637 1.00 35.93  ? 368 TYR C N     1 
ATOM   6135  C CA    . TYR C 1 397 ? 72.745  166.028 142.498 1.00 35.93  ? 368 TYR C CA    1 
ATOM   6136  C C     . TYR C 1 397 ? 71.354  165.481 142.785 1.00 35.93  ? 368 TYR C C     1 
ATOM   6137  O O     . TYR C 1 397 ? 71.185  164.498 143.512 1.00 35.93  ? 368 TYR C O     1 
ATOM   6138  C CB    . TYR C 1 397 ? 73.306  165.316 141.269 1.00 35.93  ? 368 TYR C CB    1 
ATOM   6139  C CG    . TYR C 1 397 ? 74.680  165.779 140.887 1.00 35.93  ? 368 TYR C CG    1 
ATOM   6140  C CD1   . TYR C 1 397 ? 74.860  166.933 140.143 1.00 35.93  ? 368 TYR C CD1   1 
ATOM   6141  C CD2   . TYR C 1 397 ? 75.798  165.058 141.263 1.00 35.93  ? 368 TYR C CD2   1 
ATOM   6142  C CE1   . TYR C 1 397 ? 76.115  167.359 139.793 1.00 35.93  ? 368 TYR C CE1   1 
ATOM   6143  C CE2   . TYR C 1 397 ? 77.054  165.474 140.916 1.00 35.93  ? 368 TYR C CE2   1 
ATOM   6144  C CZ    . TYR C 1 397 ? 77.207  166.625 140.184 1.00 35.93  ? 368 TYR C CZ    1 
ATOM   6145  O OH    . TYR C 1 397 ? 78.468  167.038 139.840 1.00 35.93  ? 368 TYR C OH    1 
ATOM   6146  N N     . ASP C 1 398 ? 70.359  166.131 142.195 1.00 39.36  ? 369 ASP C N     1 
ATOM   6147  C CA    . ASP C 1 398 ? 69.013  165.582 142.110 1.00 39.36  ? 369 ASP C CA    1 
ATOM   6148  C C     . ASP C 1 398 ? 68.995  164.486 141.046 1.00 39.36  ? 369 ASP C C     1 
ATOM   6149  O O     . ASP C 1 398 ? 69.955  164.345 140.287 1.00 39.36  ? 369 ASP C O     1 
ATOM   6150  C CB    . ASP C 1 398 ? 68.014  166.702 141.813 1.00 39.36  ? 369 ASP C CB    1 
ATOM   6151  C CG    . ASP C 1 398 ? 68.251  167.371 140.469 1.00 39.36  ? 369 ASP C CG    1 
ATOM   6152  O OD1   . ASP C 1 398 ? 67.940  166.765 139.424 1.00 39.36  ? 369 ASP C OD1   1 
ATOM   6153  O OD2   . ASP C 1 398 ? 68.754  168.514 140.462 1.00 39.36  ? 369 ASP C OD2   1 
ATOM   6154  N N     . PRO C 1 399 ? 67.936  163.660 140.989 1.00 39.75  ? 370 PRO C N     1 
ATOM   6155  C CA    . PRO C 1 399 ? 67.921  162.564 139.997 1.00 39.75  ? 370 PRO C CA    1 
ATOM   6156  C C     . PRO C 1 399 ? 67.984  163.005 138.541 1.00 39.75  ? 370 PRO C C     1 
ATOM   6157  O O     . PRO C 1 399 ? 68.572  162.286 137.724 1.00 39.75  ? 370 PRO C O     1 
ATOM   6158  C CB    . PRO C 1 399 ? 66.597  161.846 140.293 1.00 39.75  ? 370 PRO C CB    1 
ATOM   6159  C CG    . PRO C 1 399 ? 66.300  162.158 141.691 1.00 39.75  ? 370 PRO C CG    1 
ATOM   6160  C CD    . PRO C 1 399 ? 66.790  163.551 141.912 1.00 39.75  ? 370 PRO C CD    1 
ATOM   6161  N N     . SER C 1 400 ? 67.393  164.148 138.183 1.00 37.98  ? 371 SER C N     1 
ATOM   6162  C CA    . SER C 1 400 ? 67.388  164.567 136.782 1.00 37.98  ? 371 SER C CA    1 
ATOM   6163  C C     . SER C 1 400 ? 68.791  164.911 136.296 1.00 37.98  ? 371 SER C C     1 
ATOM   6164  O O     . SER C 1 400 ? 69.188  164.517 135.190 1.00 37.98  ? 371 SER C O     1 
ATOM   6165  C CB    . SER C 1 400 ? 66.453  165.760 136.594 1.00 37.98  ? 371 SER C CB    1 
ATOM   6166  O OG    . SER C 1 400 ? 66.627  166.342 135.315 1.00 37.98  ? 371 SER C OG    1 
ATOM   6167  N N     . GLU C 1 401 ? 69.558  165.638 137.113 1.00 40.25  ? 372 GLU C N     1 
ATOM   6168  C CA    . GLU C 1 401 ? 70.933  165.961 136.750 1.00 40.25  ? 372 GLU C CA    1 
ATOM   6169  C C     . GLU C 1 401 ? 71.780  164.701 136.642 1.00 40.25  ? 372 GLU C C     1 
ATOM   6170  O O     . GLU C 1 401 ? 72.597  164.572 135.726 1.00 40.25  ? 372 GLU C O     1 
ATOM   6171  C CB    . GLU C 1 401 ? 71.531  166.924 137.774 1.00 40.25  ? 372 GLU C CB    1 
ATOM   6172  C CG    . GLU C 1 401 ? 70.881  168.296 137.777 1.00 40.25  ? 372 GLU C CG    1 
ATOM   6173  C CD    . GLU C 1 401 ? 71.506  169.238 138.786 1.00 40.25  ? 372 GLU C CD    1 
ATOM   6174  O OE1   . GLU C 1 401 ? 72.115  168.752 139.761 1.00 40.25  ? 372 GLU C OE1   1 
ATOM   6175  O OE2   . GLU C 1 401 ? 71.385  170.468 138.607 1.00 40.25  ? 372 GLU C OE2   1 
ATOM   6176  N N     . MET C 1 402 ? 71.583  163.754 137.560 1.00 38.88  ? 373 MET C N     1 
ATOM   6177  C CA    . MET C 1 402 ? 72.337  162.507 137.516 1.00 38.88  ? 373 MET C CA    1 
ATOM   6178  C C     . MET C 1 402 ? 71.996  161.697 136.270 1.00 38.88  ? 373 MET C C     1 
ATOM   6179  O O     . MET C 1 402 ? 72.878  161.074 135.665 1.00 38.88  ? 373 MET C O     1 
ATOM   6180  C CB    . MET C 1 402 ? 72.059  161.698 138.779 1.00 38.88  ? 373 MET C CB    1 
ATOM   6181  C CG    . MET C 1 402 ? 73.003  160.511 138.970 1.00 38.88  ? 373 MET C CG    1 
ATOM   6182  S SD    . MET C 1 402 ? 73.083  159.673 140.581 1.00 38.88  ? 373 MET C SD    1 
ATOM   6183  C CE    . MET C 1 402 ? 72.783  160.941 141.814 1.00 38.88  ? 373 MET C CE    1 
ATOM   6184  N N     . ILE C 1 403 ? 70.724  161.695 135.869 1.00 41.06  ? 374 ILE C N     1 
ATOM   6185  C CA    . ILE C 1 403 ? 70.336  160.995 134.649 1.00 41.06  ? 374 ILE C CA    1 
ATOM   6186  C C     . ILE C 1 403 ? 70.957  161.675 133.434 1.00 41.06  ? 374 ILE C C     1 
ATOM   6187  O O     . ILE C 1 403 ? 71.363  161.007 132.476 1.00 41.06  ? 374 ILE C O     1 
ATOM   6188  C CB    . ILE C 1 403 ? 68.799  160.910 134.548 1.00 41.06  ? 374 ILE C CB    1 
ATOM   6189  C CG1   . ILE C 1 403 ? 68.252  159.909 135.573 1.00 41.06  ? 374 ILE C CG1   1 
ATOM   6190  C CG2   . ILE C 1 403 ? 68.347  160.484 133.145 1.00 41.06  ? 374 ILE C CG2   1 
ATOM   6191  C CD1   . ILE C 1 403 ? 66.821  160.174 135.993 1.00 41.06  ? 374 ILE C CD1   1 
ATOM   6192  N N     . GLN C 1 404 ? 71.046  163.008 133.453 1.00 38.95  ? 375 GLN C N     1 
ATOM   6193  C CA    . GLN C 1 404 ? 71.730  163.713 132.371 1.00 38.95  ? 375 GLN C CA    1 
ATOM   6194  C C     . GLN C 1 404 ? 73.210  163.344 132.317 1.00 38.95  ? 375 GLN C C     1 
ATOM   6195  O O     . GLN C 1 404 ? 73.784  163.197 131.230 1.00 38.95  ? 375 GLN C O     1 
ATOM   6196  C CB    . GLN C 1 404 ? 71.559  165.222 132.537 1.00 38.95  ? 375 GLN C CB    1 
ATOM   6197  C CG    . GLN C 1 404 ? 70.200  165.738 132.093 1.00 38.95  ? 375 GLN C CG    1 
ATOM   6198  C CD    . GLN C 1 404 ? 69.913  167.141 132.591 1.00 38.95  ? 375 GLN C CD    1 
ATOM   6199  O OE1   . GLN C 1 404 ? 70.321  168.125 131.976 1.00 38.95  ? 375 GLN C OE1   1 
ATOM   6200  N NE2   . GLN C 1 404 ? 69.202  167.238 133.708 1.00 38.95  ? 375 GLN C NE2   1 
ATOM   6201  N N     . ILE C 1 405 ? 73.839  163.187 133.485 1.00 36.09  ? 376 ILE C N     1 
ATOM   6202  C CA    . ILE C 1 405 ? 75.244  162.780 133.544 1.00 36.09  ? 376 ILE C CA    1 
ATOM   6203  C C     . ILE C 1 405 ? 75.422  161.390 132.948 1.00 36.09  ? 376 ILE C C     1 
ATOM   6204  O O     . ILE C 1 405 ? 76.360  161.140 132.178 1.00 36.09  ? 376 ILE C O     1 
ATOM   6205  C CB    . ILE C 1 405 ? 75.751  162.836 135.001 1.00 36.09  ? 376 ILE C CB    1 
ATOM   6206  C CG1   . ILE C 1 405 ? 75.883  164.289 135.492 1.00 36.09  ? 376 ILE C CG1   1 
ATOM   6207  C CG2   . ILE C 1 405 ? 77.057  162.023 135.205 1.00 36.09  ? 376 ILE C CG2   1 
ATOM   6208  C CD1   . ILE C 1 405 ? 76.945  165.130 134.824 1.00 36.09  ? 376 ILE C CD1   1 
ATOM   6209  N N     . ILE C 1 406 ? 74.547  160.458 133.328 1.00 38.34  ? 377 ILE C N     1 
ATOM   6210  C CA    . ILE C 1 406 ? 74.665  159.095 132.818 1.00 38.34  ? 377 ILE C CA    1 
ATOM   6211  C C     . ILE C 1 406 ? 74.405  159.076 131.318 1.00 38.34  ? 377 ILE C C     1 
ATOM   6212  O O     . ILE C 1 406 ? 75.040  158.313 130.584 1.00 38.34  ? 377 ILE C O     1 
ATOM   6213  C CB    . ILE C 1 406 ? 73.724  158.133 133.575 1.00 38.34  ? 377 ILE C CB    1 
ATOM   6214  C CG1   . ILE C 1 406 ? 74.072  158.044 135.074 1.00 38.34  ? 377 ILE C CG1   1 
ATOM   6215  C CG2   . ILE C 1 406 ? 73.774  156.735 132.964 1.00 38.34  ? 377 ILE C CG2   1 
ATOM   6216  C CD1   . ILE C 1 406 ? 75.313  157.222 135.414 1.00 38.34  ? 377 ILE C CD1   1 
ATOM   6217  N N     . ALA C 1 407 ? 73.494  159.925 130.832 1.00 38.57  ? 378 ALA C N     1 
ATOM   6218  C CA    . ALA C 1 407 ? 73.268  160.029 129.394 1.00 38.57  ? 378 ALA C CA    1 
ATOM   6219  C C     . ALA C 1 407 ? 74.505  160.547 128.669 1.00 38.57  ? 378 ALA C C     1 
ATOM   6220  O O     . ALA C 1 407 ? 74.859  160.039 127.597 1.00 38.57  ? 378 ALA C O     1 
ATOM   6221  C CB    . ALA C 1 407 ? 72.071  160.937 129.118 1.00 38.57  ? 378 ALA C CB    1 
ATOM   6222  N N     . ILE C 1 408 ? 75.171  161.560 129.237 1.00 39.81  ? 379 ILE C N     1 
ATOM   6223  C CA    . ILE C 1 408 ? 76.369  162.122 128.609 1.00 39.81  ? 379 ILE C CA    1 
ATOM   6224  C C     . ILE C 1 408 ? 77.477  161.076 128.557 1.00 39.81  ? 379 ILE C C     1 
ATOM   6225  O O     . ILE C 1 408 ? 78.165  160.923 127.536 1.00 39.81  ? 379 ILE C O     1 
ATOM   6226  C CB    . ILE C 1 408 ? 76.817  163.399 129.352 1.00 39.81  ? 379 ILE C CB    1 
ATOM   6227  C CG1   . ILE C 1 408 ? 75.842  164.549 129.073 1.00 39.81  ? 379 ILE C CG1   1 
ATOM   6228  C CG2   . ILE C 1 408 ? 78.232  163.830 128.925 1.00 39.81  ? 379 ILE C CG2   1 
ATOM   6229  C CD1   . ILE C 1 408 ? 75.854  165.653 130.115 1.00 39.81  ? 379 ILE C CD1   1 
ATOM   6230  N N     . ARG C 1 409 ? 77.664  160.338 129.654 1.00 40.05  ? 380 ARG C N     1 
ATOM   6231  C CA    . ARG C 1 409 ? 78.647  159.259 129.652 1.00 40.05  ? 380 ARG C CA    1 
ATOM   6232  C C     . ARG C 1 409 ? 78.260  158.155 128.677 1.00 40.05  ? 380 ARG C C     1 
ATOM   6233  O O     . ARG C 1 409 ? 79.138  157.497 128.107 1.00 40.05  ? 380 ARG C O     1 
ATOM   6234  C CB    . ARG C 1 409 ? 78.805  158.684 131.061 1.00 40.05  ? 380 ARG C CB    1 
ATOM   6235  C CG    . ARG C 1 409 ? 79.552  159.577 132.061 1.00 40.05  ? 380 ARG C CG    1 
ATOM   6236  C CD    . ARG C 1 409 ? 81.015  159.851 131.699 1.00 40.05  ? 380 ARG C CD    1 
ATOM   6237  N NE    . ARG C 1 409 ? 81.767  158.639 131.383 1.00 40.05  ? 380 ARG C NE    1 
ATOM   6238  C CZ    . ARG C 1 409 ? 82.903  158.585 130.694 1.00 40.05  ? 380 ARG C CZ    1 
ATOM   6239  N NH1   . ARG C 1 409 ? 83.494  159.674 130.220 1.00 40.05  ? 380 ARG C NH1   1 
ATOM   6240  N NH2   . ARG C 1 409 ? 83.469  157.402 130.477 1.00 40.05  ? 380 ARG C NH2   1 
ATOM   6241  N N     . ALA C 1 410 ? 76.960  157.932 128.474 1.00 42.06  ? 381 ALA C N     1 
ATOM   6242  C CA    . ALA C 1 410 ? 76.527  156.946 127.492 1.00 42.06  ? 381 ALA C CA    1 
ATOM   6243  C C     . ALA C 1 410 ? 76.896  157.374 126.078 1.00 42.06  ? 381 ALA C C     1 
ATOM   6244  O O     . ALA C 1 410 ? 77.359  156.549 125.282 1.00 42.06  ? 381 ALA C O     1 
ATOM   6245  C CB    . ALA C 1 410 ? 75.021  156.716 127.607 1.00 42.06  ? 381 ALA C CB    1 
ATOM   6246  N N     . GLN C 1 411 ? 76.703  158.655 125.743 1.00 42.62  ? 382 GLN C N     1 
ATOM   6247  C CA    . GLN C 1 411 ? 77.057  159.089 124.386 1.00 42.62  ? 382 GLN C CA    1 
ATOM   6248  C C     . GLN C 1 411 ? 78.566  159.073 124.191 1.00 42.62  ? 382 GLN C C     1 
ATOM   6249  O O     . GLN C 1 411 ? 79.052  158.719 123.111 1.00 42.62  ? 382 GLN C O     1 
ATOM   6250  C CB    . GLN C 1 411 ? 76.539  160.491 124.017 1.00 42.62  ? 382 GLN C CB    1 
ATOM   6251  C CG    . GLN C 1 411 ? 75.392  161.104 124.791 1.00 42.62  ? 382 GLN C CG    1 
ATOM   6252  C CD    . GLN C 1 411 ? 74.917  162.421 124.204 1.00 42.62  ? 382 GLN C CD    1 
ATOM   6253  O OE1   . GLN C 1 411 ? 75.106  162.695 123.019 1.00 42.62  ? 382 GLN C OE1   1 
ATOM   6254  N NE2   . GLN C 1 411 ? 74.305  163.251 125.041 1.00 42.62  ? 382 GLN C NE2   1 
ATOM   6255  N N     . VAL C 1 412 ? 79.321  159.463 125.220 1.00 41.06  ? 383 VAL C N     1 
ATOM   6256  C CA    . VAL C 1 412 ? 80.768  159.586 125.062 1.00 41.06  ? 383 VAL C CA    1 
ATOM   6257  C C     . VAL C 1 412 ? 81.413  158.215 124.885 1.00 41.06  ? 383 VAL C C     1 
ATOM   6258  O O     . VAL C 1 412 ? 82.409  158.082 124.164 1.00 41.06  ? 383 VAL C O     1 
ATOM   6259  C CB    . VAL C 1 412 ? 81.363  160.366 126.251 1.00 41.06  ? 383 VAL C CB    1 
ATOM   6260  C CG1   . VAL C 1 412 ? 82.897  160.274 126.278 1.00 41.06  ? 383 VAL C CG1   1 
ATOM   6261  C CG2   . VAL C 1 412 ? 80.911  161.838 126.201 1.00 41.06  ? 383 VAL C CG2   1 
ATOM   6262  N N     . GLU C 1 413 ? 80.866  157.181 125.525 1.00 45.61  ? 384 GLU C N     1 
ATOM   6263  C CA    . GLU C 1 413 ? 81.332  155.808 125.347 1.00 45.61  ? 384 GLU C CA    1 
ATOM   6264  C C     . GLU C 1 413 ? 80.749  155.129 124.094 1.00 45.61  ? 384 GLU C C     1 
ATOM   6265  O O     . GLU C 1 413 ? 80.981  153.931 123.898 1.00 45.61  ? 384 GLU C O     1 
ATOM   6266  C CB    . GLU C 1 413 ? 81.001  154.987 126.605 1.00 45.61  ? 384 GLU C CB    1 
ATOM   6267  C CG    . GLU C 1 413 ? 81.967  155.222 127.787 1.00 45.61  ? 384 GLU C CG    1 
ATOM   6268  C CD    . GLU C 1 413 ? 81.982  154.099 128.829 1.00 45.61  ? 384 GLU C CD    1 
ATOM   6269  O OE1   . GLU C 1 413 ? 81.638  152.939 128.515 1.00 45.61  ? 384 GLU C OE1   1 
ATOM   6270  O OE2   . GLU C 1 413 ? 82.351  154.386 129.987 1.00 45.61  ? 384 GLU C OE2   1 
ATOM   6271  N N     . GLU C 1 414 ? 80.026  155.860 123.238 1.00 48.88  ? 385 GLU C N     1 
ATOM   6272  C CA    . GLU C 1 414 ? 79.413  155.342 122.015 1.00 48.88  ? 385 GLU C CA    1 
ATOM   6273  C C     . GLU C 1 414 ? 78.325  154.309 122.293 1.00 48.88  ? 385 GLU C C     1 
ATOM   6274  O O     . GLU C 1 414 ? 78.058  153.457 121.440 1.00 48.88  ? 385 GLU C O     1 
ATOM   6275  C CB    . GLU C 1 414 ? 80.453  154.739 121.053 1.00 48.88  ? 385 GLU C CB    1 
ATOM   6276  C CG    . GLU C 1 414 ? 81.703  155.591 120.781 1.00 48.88  ? 385 GLU C CG    1 
ATOM   6277  C CD    . GLU C 1 414 ? 81.415  156.839 119.965 1.00 48.88  ? 385 GLU C CD    1 
ATOM   6278  O OE1   . GLU C 1 414 ? 80.245  157.064 119.593 1.00 48.88  ? 385 GLU C OE1   1 
ATOM   6279  O OE2   . GLU C 1 414 ? 82.368  157.598 119.691 1.00 48.88  ? 385 GLU C OE2   1 
ATOM   6280  N N     . LEU C 1 415 ? 77.686  154.372 123.461 1.00 46.63  ? 386 LEU C N     1 
ATOM   6281  C CA    . LEU C 1 415 ? 76.573  153.503 123.814 1.00 46.63  ? 386 LEU C CA    1 
ATOM   6282  C C     . LEU C 1 415 ? 75.247  154.189 123.506 1.00 46.63  ? 386 LEU C C     1 
ATOM   6283  O O     . LEU C 1 415 ? 75.161  155.416 123.416 1.00 46.63  ? 386 LEU C O     1 
ATOM   6284  C CB    . LEU C 1 415 ? 76.622  153.122 125.295 1.00 46.63  ? 386 LEU C CB    1 
ATOM   6285  C CG    . LEU C 1 415 ? 77.428  151.873 125.668 1.00 46.63  ? 386 LEU C CG    1 
ATOM   6286  C CD1   . LEU C 1 415 ? 78.849  151.926 125.125 1.00 46.63  ? 386 LEU C CD1   1 
ATOM   6287  C CD2   . LEU C 1 415 ? 77.439  151.691 127.179 1.00 46.63  ? 386 LEU C CD2   1 
ATOM   6288  N N     . THR C 1 416 ? 74.212  153.368 123.340 1.00 53.38  ? 387 THR C N     1 
ATOM   6289  C CA    . THR C 1 416 ? 72.841  153.811 123.119 1.00 53.38  ? 387 THR C CA    1 
ATOM   6290  C C     . THR C 1 416 ? 71.992  153.427 124.323 1.00 53.38  ? 387 THR C C     1 
ATOM   6291  O O     . THR C 1 416 ? 72.105  152.311 124.840 1.00 53.38  ? 387 THR C O     1 
ATOM   6292  C CB    . THR C 1 416 ? 72.262  153.190 121.846 1.00 53.38  ? 387 THR C CB    1 
ATOM   6293  O OG1   . THR C 1 416 ? 72.303  151.761 121.943 1.00 53.38  ? 387 THR C OG1   1 
ATOM   6294  C CG2   . THR C 1 416 ? 73.057  153.635 120.628 1.00 53.38  ? 387 THR C CG2   1 
ATOM   6295  N N     . VAL C 1 417 ? 71.150  154.362 124.768 1.00 51.17  ? 388 VAL C N     1 
ATOM   6296  C CA    . VAL C 1 417 ? 70.363  154.222 125.988 1.00 51.17  ? 388 VAL C CA    1 
ATOM   6297  C C     . VAL C 1 417 ? 68.979  154.815 125.752 1.00 51.17  ? 388 VAL C C     1 
ATOM   6298  O O     . VAL C 1 417 ? 68.724  155.479 124.745 1.00 51.17  ? 388 VAL C O     1 
ATOM   6299  C CB    . VAL C 1 417 ? 71.050  154.893 127.202 1.00 51.17  ? 388 VAL C CB    1 
ATOM   6300  C CG1   . VAL C 1 417 ? 72.190  154.026 127.711 1.00 51.17  ? 388 VAL C CG1   1 
ATOM   6301  C CG2   . VAL C 1 417 ? 71.568  156.292 126.848 1.00 51.17  ? 388 VAL C CG2   1 
ATOM   6302  N N     . ASP C 1 418 ? 68.079  154.553 126.702 1.00 56.79  ? 389 ASP C N     1 
ATOM   6303  C CA    . ASP C 1 418 ? 66.705  155.036 126.675 1.00 56.79  ? 389 ASP C CA    1 
ATOM   6304  C C     . ASP C 1 418 ? 66.314  155.440 128.091 1.00 56.79  ? 389 ASP C C     1 
ATOM   6305  O O     . ASP C 1 418 ? 66.999  155.108 129.060 1.00 56.79  ? 389 ASP C O     1 
ATOM   6306  C CB    . ASP C 1 418 ? 65.754  153.963 126.112 1.00 56.79  ? 389 ASP C CB    1 
ATOM   6307  C CG    . ASP C 1 418 ? 64.411  154.527 125.643 1.00 56.79  ? 389 ASP C CG    1 
ATOM   6308  O OD1   . ASP C 1 418 ? 64.208  155.760 125.675 1.00 56.79  ? 389 ASP C OD1   1 
ATOM   6309  O OD2   . ASP C 1 418 ? 63.549  153.721 125.236 1.00 56.79  ? 389 ASP C OD2   1 
ATOM   6310  N N     . GLU C 1 419 ? 65.210  156.184 128.203 1.00 57.70  ? 390 GLU C N     1 
ATOM   6311  C CA    . GLU C 1 419 ? 64.784  156.702 129.502 1.00 57.70  ? 390 GLU C CA    1 
ATOM   6312  C C     . GLU C 1 419 ? 64.430  155.587 130.480 1.00 57.70  ? 390 GLU C C     1 
ATOM   6313  O O     . GLU C 1 419 ? 64.638  155.743 131.691 1.00 57.70  ? 390 GLU C O     1 
ATOM   6314  C CB    . GLU C 1 419 ? 63.589  157.641 129.328 1.00 57.70  ? 390 GLU C CB    1 
ATOM   6315  C CG    . GLU C 1 419 ? 63.953  159.072 128.937 1.00 57.70  ? 390 GLU C CG    1 
ATOM   6316  C CD    . GLU C 1 419 ? 64.452  159.201 127.506 1.00 57.70  ? 390 GLU C CD    1 
ATOM   6317  O OE1   . GLU C 1 419 ? 64.811  158.175 126.891 1.00 57.70  ? 390 GLU C OE1   1 
ATOM   6318  O OE2   . GLU C 1 419 ? 64.481  160.340 126.995 1.00 57.70  ? 390 GLU C OE2   1 
ATOM   6319  N N     . GLU C 1 420 ? 63.909  154.462 129.977 1.00 60.59  ? 391 GLU C N     1 
ATOM   6320  C CA    . GLU C 1 420 ? 63.476  153.375 130.855 1.00 60.59  ? 391 GLU C CA    1 
ATOM   6321  C C     . GLU C 1 420 ? 64.646  152.776 131.630 1.00 60.59  ? 391 GLU C C     1 
ATOM   6322  O O     . GLU C 1 420 ? 64.501  152.431 132.809 1.00 60.59  ? 391 GLU C O     1 
ATOM   6323  C CB    . GLU C 1 420 ? 62.748  152.294 130.045 1.00 60.59  ? 391 GLU C CB    1 
ATOM   6324  C CG    . GLU C 1 420 ? 63.517  151.690 128.862 1.00 60.59  ? 391 GLU C CG    1 
ATOM   6325  C CD    . GLU C 1 420 ? 62.785  150.523 128.227 1.00 60.59  ? 391 GLU C CD    1 
ATOM   6326  O OE1   . GLU C 1 420 ? 61.661  150.729 127.723 1.00 60.59  ? 391 GLU C OE1   1 
ATOM   6327  O OE2   . GLU C 1 420 ? 63.334  149.401 128.231 1.00 60.59  ? 391 GLU C OE2   1 
ATOM   6328  N N     . CYS C 1 421 ? 65.812  152.656 130.991 1.00 55.04  ? 392 CYS C N     1 
ATOM   6329  C CA    . CYS C 1 421 ? 67.020  152.175 131.655 1.00 55.04  ? 392 CYS C CA    1 
ATOM   6330  C C     . CYS C 1 421 ? 67.803  153.296 132.322 1.00 55.04  ? 392 CYS C C     1 
ATOM   6331  O O     . CYS C 1 421 ? 68.438  153.067 133.359 1.00 55.04  ? 392 CYS C O     1 
ATOM   6332  C CB    . CYS C 1 421 ? 67.916  151.447 130.649 1.00 55.04  ? 392 CYS C CB    1 
ATOM   6333  S SG    . CYS C 1 421 ? 67.921  152.156 128.991 1.00 55.04  ? 392 CYS C SG    1 
ATOM   6334  N N     . LEU C 1 422 ? 67.766  154.505 131.754 1.00 47.70  ? 393 LEU C N     1 
ATOM   6335  C CA    . LEU C 1 422 ? 68.477  155.627 132.354 1.00 47.70  ? 393 LEU C CA    1 
ATOM   6336  C C     . LEU C 1 422 ? 67.896  156.008 133.708 1.00 47.70  ? 393 LEU C C     1 
ATOM   6337  O O     . LEU C 1 422 ? 68.645  156.418 134.599 1.00 47.70  ? 393 LEU C O     1 
ATOM   6338  C CB    . LEU C 1 422 ? 68.446  156.838 131.420 1.00 47.70  ? 393 LEU C CB    1 
ATOM   6339  C CG    . LEU C 1 422 ? 69.393  156.899 130.216 1.00 47.70  ? 393 LEU C CG    1 
ATOM   6340  C CD1   . LEU C 1 422 ? 69.124  158.161 129.407 1.00 47.70  ? 393 LEU C CD1   1 
ATOM   6341  C CD2   . LEU C 1 422 ? 70.849  156.854 130.633 1.00 47.70  ? 393 LEU C CD2   1 
ATOM   6342  N N     . VAL C 1 423 ? 66.577  155.895 133.882 1.00 49.51  ? 394 VAL C N     1 
ATOM   6343  C CA    . VAL C 1 423 ? 65.973  156.210 135.176 1.00 49.51  ? 394 VAL C CA    1 
ATOM   6344  C C     . VAL C 1 423 ? 66.455  155.227 136.238 1.00 49.51  ? 394 VAL C C     1 
ATOM   6345  O O     . VAL C 1 423 ? 66.775  155.617 137.370 1.00 49.51  ? 394 VAL C O     1 
ATOM   6346  C CB    . VAL C 1 423 ? 64.435  156.223 135.057 1.00 49.51  ? 394 VAL C CB    1 
ATOM   6347  C CG1   . VAL C 1 423 ? 63.756  156.211 136.436 1.00 49.51  ? 394 VAL C CG1   1 
ATOM   6348  C CG2   . VAL C 1 423 ? 63.963  157.439 134.253 1.00 49.51  ? 394 VAL C CG2   1 
ATOM   6349  N N     . LEU C 1 424 ? 66.514  153.940 135.892 1.00 49.11  ? 395 LEU C N     1 
ATOM   6350  C CA    . LEU C 1 424 ? 67.001  152.940 136.835 1.00 49.11  ? 395 LEU C CA    1 
ATOM   6351  C C     . LEU C 1 424 ? 68.477  153.175 137.142 1.00 49.11  ? 395 LEU C C     1 
ATOM   6352  O O     . LEU C 1 424 ? 68.906  153.044 138.294 1.00 49.11  ? 395 LEU C O     1 
ATOM   6353  C CB    . LEU C 1 424 ? 66.777  151.542 136.256 1.00 49.11  ? 395 LEU C CB    1 
ATOM   6354  C CG    . LEU C 1 424 ? 67.346  150.290 136.936 1.00 49.11  ? 395 LEU C CG    1 
ATOM   6355  C CD1   . LEU C 1 424 ? 67.166  150.272 138.458 1.00 49.11  ? 395 LEU C CD1   1 
ATOM   6356  C CD2   . LEU C 1 424 ? 66.741  149.037 136.320 1.00 49.11  ? 395 LEU C CD2   1 
ATOM   6357  N N     . LEU C 1 425 ? 69.263  153.552 136.127 1.00 44.84  ? 396 LEU C N     1 
ATOM   6358  C CA    . LEU C 1 425 ? 70.671  153.874 136.359 1.00 44.84  ? 396 LEU C CA    1 
ATOM   6359  C C     . LEU C 1 425 ? 70.819  155.077 137.282 1.00 44.84  ? 396 LEU C C     1 
ATOM   6360  O O     . LEU C 1 425 ? 71.711  155.104 138.136 1.00 44.84  ? 396 LEU C O     1 
ATOM   6361  C CB    . LEU C 1 425 ? 71.388  154.141 135.031 1.00 44.84  ? 396 LEU C CB    1 
ATOM   6362  C CG    . LEU C 1 425 ? 71.962  152.959 134.237 1.00 44.84  ? 396 LEU C CG    1 
ATOM   6363  C CD1   . LEU C 1 425 ? 72.523  153.409 132.894 1.00 44.84  ? 396 LEU C CD1   1 
ATOM   6364  C CD2   . LEU C 1 425 ? 73.049  152.226 135.014 1.00 44.84  ? 396 LEU C CD2   1 
ATOM   6365  N N     . GLY C 1 426 ? 69.958  156.081 137.125 1.00 45.26  ? 397 GLY C N     1 
ATOM   6366  C CA    . GLY C 1 426 ? 69.993  157.221 138.025 1.00 45.26  ? 397 GLY C CA    1 
ATOM   6367  C C     . GLY C 1 426 ? 69.637  156.845 139.450 1.00 45.26  ? 397 GLY C C     1 
ATOM   6368  O O     . GLY C 1 426 ? 70.241  157.346 140.403 1.00 45.26  ? 397 GLY C O     1 
ATOM   6369  N N     . GLU C 1 427 ? 68.654  155.956 139.616 1.00 48.29  ? 398 GLU C N     1 
ATOM   6370  C CA    . GLU C 1 427 ? 68.322  155.466 140.953 1.00 48.29  ? 398 GLU C CA    1 
ATOM   6371  C C     . GLU C 1 427 ? 69.488  154.695 141.563 1.00 48.29  ? 398 GLU C C     1 
ATOM   6372  O O     . GLU C 1 427 ? 69.769  154.823 142.761 1.00 48.29  ? 398 GLU C O     1 
ATOM   6373  C CB    . GLU C 1 427 ? 67.073  154.586 140.898 1.00 48.29  ? 398 GLU C CB    1 
ATOM   6374  C CG    . GLU C 1 427 ? 65.781  155.344 140.613 1.00 48.29  ? 398 GLU C CG    1 
ATOM   6375  C CD    . GLU C 1 427 ? 64.550  154.641 141.157 1.00 48.29  ? 398 GLU C CD    1 
ATOM   6376  O OE1   . GLU C 1 427 ? 64.590  153.405 141.333 1.00 48.29  ? 398 GLU C OE1   1 
ATOM   6377  O OE2   . GLU C 1 427 ? 63.538  155.329 141.406 1.00 48.29  ? 398 GLU C OE2   1 
ATOM   6378  N N     . ILE C 1 428 ? 70.173  153.885 140.752 1.00 46.05  ? 399 ILE C N     1 
ATOM   6379  C CA    . ILE C 1 428 ? 71.323  153.129 141.241 1.00 46.05  ? 399 ILE C CA    1 
ATOM   6380  C C     . ILE C 1 428 ? 72.450  154.077 141.629 1.00 46.05  ? 399 ILE C C     1 
ATOM   6381  O O     . ILE C 1 428 ? 73.160  153.851 142.616 1.00 46.05  ? 399 ILE C O     1 
ATOM   6382  C CB    . ILE C 1 428 ? 71.787  152.104 140.184 1.00 46.05  ? 399 ILE C CB    1 
ATOM   6383  C CG1   . ILE C 1 428 ? 70.739  151.006 139.964 1.00 46.05  ? 399 ILE C CG1   1 
ATOM   6384  C CG2   . ILE C 1 428 ? 73.114  151.454 140.595 1.00 46.05  ? 399 ILE C CG2   1 
ATOM   6385  C CD1   . ILE C 1 428 ? 70.784  150.411 138.577 1.00 46.05  ? 399 ILE C CD1   1 
ATOM   6386  N N     . GLY C 1 429 ? 72.645  155.139 140.848 1.00 41.03  ? 400 GLY C N     1 
ATOM   6387  C CA    . GLY C 1 429 ? 73.655  156.122 141.195 1.00 41.03  ? 400 GLY C CA    1 
ATOM   6388  C C     . GLY C 1 429 ? 73.324  156.859 142.477 1.00 41.03  ? 400 GLY C C     1 
ATOM   6389  O O     . GLY C 1 429 ? 74.213  157.173 143.272 1.00 41.03  ? 400 GLY C O     1 
ATOM   6390  N N     . GLN C 1 430 ? 72.041  157.160 142.685 1.00 46.37  ? 401 GLN C N     1 
ATOM   6391  C CA    . GLN C 1 430 ? 71.620  157.790 143.931 1.00 46.37  ? 401 GLN C CA    1 
ATOM   6392  C C     . GLN C 1 430 ? 71.854  156.866 145.119 1.00 46.37  ? 401 GLN C C     1 
ATOM   6393  O O     . GLN C 1 430 ? 72.329  157.306 146.172 1.00 46.37  ? 401 GLN C O     1 
ATOM   6394  C CB    . GLN C 1 430 ? 70.144  158.190 143.834 1.00 46.37  ? 401 GLN C CB    1 
ATOM   6395  C CG    . GLN C 1 430 ? 69.527  158.775 145.110 1.00 46.37  ? 401 GLN C CG    1 
ATOM   6396  C CD    . GLN C 1 430 ? 68.133  159.324 144.873 1.00 46.37  ? 401 GLN C CD    1 
ATOM   6397  O OE1   . GLN C 1 430 ? 67.960  160.305 144.153 1.00 46.37  ? 401 GLN C OE1   1 
ATOM   6398  N NE2   . GLN C 1 430 ? 67.128  158.692 145.477 1.00 46.37  ? 401 GLN C NE2   1 
ATOM   6399  N N     . ARG C 1 431 ? 71.530  155.581 144.969 1.00 49.94  ? 402 ARG C N     1 
ATOM   6400  C CA    . ARG C 1 431 ? 71.509  154.692 146.125 1.00 49.94  ? 402 ARG C CA    1 
ATOM   6401  C C     . ARG C 1 431 ? 72.899  154.210 146.529 1.00 49.94  ? 402 ARG C C     1 
ATOM   6402  O O     . ARG C 1 431 ? 73.115  153.946 147.717 1.00 49.94  ? 402 ARG C O     1 
ATOM   6403  C CB    . ARG C 1 431 ? 70.575  153.507 145.854 1.00 49.94  ? 402 ARG C CB    1 
ATOM   6404  C CG    . ARG C 1 431 ? 71.184  152.342 145.093 1.00 49.94  ? 402 ARG C CG    1 
ATOM   6405  C CD    . ARG C 1 431 ? 70.107  151.446 144.505 1.00 49.94  ? 402 ARG C CD    1 
ATOM   6406  N NE    . ARG C 1 431 ? 69.162  150.988 145.520 1.00 49.94  ? 402 ARG C NE    1 
ATOM   6407  C CZ    . ARG C 1 431 ? 69.370  149.998 146.382 1.00 49.94  ? 402 ARG C CZ    1 
ATOM   6408  N NH1   . ARG C 1 431 ? 70.504  149.309 146.406 1.00 49.94  ? 402 ARG C NH1   1 
ATOM   6409  N NH2   . ARG C 1 431 ? 68.412  149.688 147.251 1.00 49.94  ? 402 ARG C NH2   1 
ATOM   6410  N N     . THR C 1 432 ? 73.862  154.204 145.585 1.00 44.69  ? 403 THR C N     1 
ATOM   6411  C CA    . THR C 1 432 ? 75.285  153.871 145.872 1.00 44.69  ? 403 THR C CA    1 
ATOM   6412  C C     . THR C 1 432 ? 76.151  155.075 145.525 1.00 44.69  ? 403 THR C C     1 
ATOM   6413  O O     . THR C 1 432 ? 76.483  155.809 146.473 1.00 44.69  ? 403 THR C O     1 
ATOM   6414  C CB    . THR C 1 432 ? 75.775  152.591 145.190 1.00 44.69  ? 403 THR C CB    1 
ATOM   6415  O OG1   . THR C 1 432 ? 77.178  152.789 145.043 1.00 44.69  ? 403 THR C OG1   1 
ATOM   6416  C CG2   . THR C 1 432 ? 75.158  152.298 143.836 1.00 44.69  ? 403 THR C CG2   1 
ATOM   6417  N N     . SER C 1 433 ? 76.493  155.321 144.253 1.00 39.90  ? 404 SER C N     1 
ATOM   6418  C CA    . SER C 1 433 ? 77.271  156.529 143.859 1.00 39.90  ? 404 SER C CA    1 
ATOM   6419  C C     . SER C 1 433 ? 77.255  156.737 142.344 1.00 39.90  ? 404 SER C C     1 
ATOM   6420  O O     . SER C 1 433 ? 77.029  155.755 141.629 1.00 39.90  ? 404 SER C O     1 
ATOM   6421  C CB    . SER C 1 433 ? 78.678  156.433 144.336 1.00 39.90  ? 404 SER C CB    1 
ATOM   6422  O OG    . SER C 1 433 ? 79.476  157.465 143.775 1.00 39.90  ? 404 SER C OG    1 
ATOM   6423  N N     . LEU C 1 434 ? 77.531  157.953 141.875 1.00 34.09  ? 405 LEU C N     1 
ATOM   6424  C CA    . LEU C 1 434 ? 77.552  158.271 140.424 1.00 34.09  ? 405 LEU C CA    1 
ATOM   6425  C C     . LEU C 1 434 ? 78.810  157.657 139.814 1.00 34.09  ? 405 LEU C C     1 
ATOM   6426  O O     . LEU C 1 434 ? 78.879  157.575 138.581 1.00 34.09  ? 405 LEU C O     1 
ATOM   6427  C CB    . LEU C 1 434 ? 77.523  159.780 140.206 1.00 34.09  ? 405 LEU C CB    1 
ATOM   6428  C CG    . LEU C 1 434 ? 77.549  160.284 138.763 1.00 34.09  ? 405 LEU C CG    1 
ATOM   6429  C CD1   . LEU C 1 434 ? 76.461  159.650 137.924 1.00 34.09  ? 405 LEU C CD1   1 
ATOM   6430  C CD2   . LEU C 1 434 ? 77.403  161.787 138.819 1.00 34.09  ? 405 LEU C CD2   1 
ATOM   6431  N N     . ARG C 1 435 ? 79.769  157.247 140.649 1.00 37.14  ? 406 ARG C N     1 
ATOM   6432  C CA    . ARG C 1 435 ? 81.035  156.629 140.183 1.00 37.14  ? 406 ARG C CA    1 
ATOM   6433  C C     . ARG C 1 435 ? 80.801  155.125 139.967 1.00 37.14  ? 406 ARG C C     1 
ATOM   6434  O O     . ARG C 1 435 ? 81.699  154.487 139.376 1.00 37.14  ? 406 ARG C O     1 
ATOM   6435  C CB    . ARG C 1 435 ? 82.100  156.962 141.231 1.00 37.14  ? 406 ARG C CB    1 
ATOM   6436  N N     . HIS C 1 436 ? 79.653  154.587 140.407 1.00 41.04  ? 407 HIS C N     1 
ATOM   6437  C CA    . HIS C 1 436 ? 79.315  153.142 140.262 1.00 41.04  ? 407 HIS C CA    1 
ATOM   6438  C C     . HIS C 1 436 ? 78.185  152.979 139.251 1.00 41.04  ? 407 HIS C C     1 
ATOM   6439  O O     . HIS C 1 436 ? 77.966  151.846 138.815 1.00 41.04  ? 407 HIS C O     1 
ATOM   6440  C CB    . HIS C 1 436 ? 78.917  152.509 141.595 1.00 41.04  ? 407 HIS C CB    1 
ATOM   6441  C CG    . HIS C 1 436 ? 78.366  151.136 141.449 1.00 41.04  ? 407 HIS C CG    1 
ATOM   6442  N ND1   . HIS C 1 436 ? 79.165  150.020 141.350 1.00 41.04  ? 407 HIS C ND1   1 
ATOM   6443  C CD2   . HIS C 1 436 ? 77.108  150.705 141.335 1.00 41.04  ? 407 HIS C CD2   1 
ATOM   6444  C CE1   . HIS C 1 436 ? 78.398  148.950 141.206 1.00 41.04  ? 407 HIS C CE1   1 
ATOM   6445  N NE2   . HIS C 1 436 ? 77.145  149.345 141.193 1.00 41.04  ? 407 HIS C NE2   1 
ATOM   6446  N N     . ALA C 1 437 ? 77.499  154.055 138.883 1.00 37.77  ? 408 ALA C N     1 
ATOM   6447  C CA    . ALA C 1 437 ? 76.422  154.012 137.875 1.00 37.77  ? 408 ALA C CA    1 
ATOM   6448  C C     . ALA C 1 437 ? 77.024  154.353 136.522 1.00 37.77  ? 408 ALA C C     1 
ATOM   6449  O O     . ALA C 1 437 ? 76.340  154.131 135.515 1.00 37.77  ? 408 ALA C O     1 
ATOM   6450  C CB    . ALA C 1 437 ? 75.343  154.973 138.244 1.00 37.77  ? 408 ALA C CB    1 
ATOM   6451  N N     . VAL C 1 438 ? 78.253  154.870 136.504 1.00 38.54  ? 409 VAL C N     1 
ATOM   6452  C CA    . VAL C 1 438 ? 78.965  155.236 135.243 1.00 38.54  ? 409 VAL C CA    1 
ATOM   6453  C C     . VAL C 1 438 ? 79.985  154.129 134.958 1.00 38.54  ? 409 VAL C C     1 
ATOM   6454  O O     . VAL C 1 438 ? 80.462  154.067 133.811 1.00 38.54  ? 409 VAL C O     1 
ATOM   6455  C CB    . VAL C 1 438 ? 79.627  156.624 135.333 1.00 38.54  ? 409 VAL C CB    1 
ATOM   6456  C CG1   . VAL C 1 438 ? 80.587  156.897 134.184 1.00 38.54  ? 409 VAL C CG1   1 
ATOM   6457  C CG2   . VAL C 1 438 ? 78.597  157.741 135.409 1.00 38.54  ? 409 VAL C CG2   1 
ATOM   6458  N N     . GLN C 1 439 ? 80.263  153.258 135.933 1.00 40.04  ? 410 GLN C N     1 
ATOM   6459  C CA    . GLN C 1 439 ? 81.186  152.111 135.726 1.00 40.04  ? 410 GLN C CA    1 
ATOM   6460  C C     . GLN C 1 439 ? 80.363  150.956 135.158 1.00 40.04  ? 410 GLN C C     1 
ATOM   6461  O O     . GLN C 1 439 ? 80.955  150.123 134.460 1.00 40.04  ? 410 GLN C O     1 
ATOM   6462  C CB    . GLN C 1 439 ? 81.912  151.666 136.996 1.00 40.04  ? 410 GLN C CB    1 
ATOM   6463  C CG    . GLN C 1 439 ? 81.286  150.476 137.717 1.00 40.04  ? 410 GLN C CG    1 
ATOM   6464  C CD    . GLN C 1 439 ? 82.027  150.088 138.976 1.00 40.04  ? 410 GLN C CD    1 
ATOM   6465  O OE1   . GLN C 1 439 ? 83.044  150.689 139.337 1.00 40.04  ? 410 GLN C OE1   1 
ATOM   6466  N NE2   . GLN C 1 439 ? 81.527  149.065 139.654 1.00 40.04  ? 410 GLN C NE2   1 
ATOM   6467  N N     . LEU C 1 440 ? 79.062  150.904 135.441 1.00 40.87  ? 411 LEU C N     1 
ATOM   6468  C CA    . LEU C 1 440 ? 78.194  149.819 134.989 1.00 40.87  ? 411 LEU C CA    1 
ATOM   6469  C C     . LEU C 1 440 ? 77.765  149.940 133.528 1.00 40.87  ? 411 LEU C C     1 
ATOM   6470  O O     . LEU C 1 440 ? 77.167  148.991 133.011 1.00 40.87  ? 411 LEU C O     1 
ATOM   6471  C CB    . LEU C 1 440 ? 76.938  149.747 135.867 1.00 40.87  ? 411 LEU C CB    1 
ATOM   6472  C CG    . LEU C 1 440 ? 77.008  149.094 137.252 1.00 40.87  ? 411 LEU C CG    1 
ATOM   6473  C CD1   . LEU C 1 440 ? 75.654  149.202 137.931 1.00 40.87  ? 411 LEU C CD1   1 
ATOM   6474  C CD2   . LEU C 1 440 ? 77.435  147.635 137.185 1.00 40.87  ? 411 LEU C CD2   1 
ATOM   6475  N N     . LEU C 1 441 ? 78.036  151.064 132.855 1.00 40.95  ? 412 LEU C N     1 
ATOM   6476  C CA    . LEU C 1 441 ? 77.521  151.256 131.500 1.00 40.95  ? 412 LEU C CA    1 
ATOM   6477  C C     . LEU C 1 441 ? 78.144  150.279 130.508 1.00 40.95  ? 412 LEU C C     1 
ATOM   6478  O O     . LEU C 1 441 ? 77.437  149.711 129.668 1.00 40.95  ? 412 LEU C O     1 
ATOM   6479  C CB    . LEU C 1 441 ? 77.763  152.695 131.037 1.00 40.95  ? 412 LEU C CB    1 
ATOM   6480  C CG    . LEU C 1 441 ? 76.708  153.750 131.390 1.00 40.95  ? 412 LEU C CG    1 
ATOM   6481  C CD1   . LEU C 1 441 ? 77.240  155.141 131.077 1.00 40.95  ? 412 LEU C CD1   1 
ATOM   6482  C CD2   . LEU C 1 441 ? 75.395  153.512 130.650 1.00 40.95  ? 412 LEU C CD2   1 
ATOM   6483  N N     . SER C 1 442 ? 79.461  150.084 130.570 1.00 44.43  ? 413 SER C N     1 
ATOM   6484  C CA    . SER C 1 442 ? 80.116  149.180 129.626 1.00 44.43  ? 413 SER C CA    1 
ATOM   6485  C C     . SER C 1 442 ? 79.678  147.725 129.776 1.00 44.43  ? 413 SER C C     1 
ATOM   6486  O O     . SER C 1 442 ? 79.319  147.110 128.754 1.00 44.43  ? 413 SER C O     1 
ATOM   6487  C CB    . SER C 1 442 ? 81.637  149.327 129.744 1.00 44.43  ? 413 SER C CB    1 
ATOM   6488  O OG    . SER C 1 442 ? 82.296  148.422 128.877 1.00 44.43  ? 413 SER C OG    1 
ATOM   6489  N N     . PRO C 1 443 ? 79.680  147.109 130.969 1.00 42.57  ? 414 PRO C N     1 
ATOM   6490  C CA    . PRO C 1 443 ? 79.158  145.734 131.062 1.00 42.57  ? 414 PRO C CA    1 
ATOM   6491  C C     . PRO C 1 443 ? 77.683  145.614 130.725 1.00 42.57  ? 414 PRO C C     1 
ATOM   6492  O O     . PRO C 1 443 ? 77.249  144.533 130.317 1.00 42.57  ? 414 PRO C O     1 
ATOM   6493  C CB    . PRO C 1 443 ? 79.437  145.336 132.519 1.00 42.57  ? 414 PRO C CB    1 
ATOM   6494  C CG    . PRO C 1 443 ? 79.731  146.581 133.226 1.00 42.57  ? 414 PRO C CG    1 
ATOM   6495  C CD    . PRO C 1 443 ? 80.327  147.507 132.233 1.00 42.57  ? 414 PRO C CD    1 
ATOM   6496  N N     . ALA C 1 444 ? 76.898  146.685 130.872 1.00 46.92  ? 415 ALA C N     1 
ATOM   6497  C CA    . ALA C 1 444 ? 75.528  146.656 130.373 1.00 46.92  ? 415 ALA C CA    1 
ATOM   6498  C C     . ALA C 1 444 ? 75.507  146.501 128.859 1.00 46.92  ? 415 ALA C C     1 
ATOM   6499  O O     . ALA C 1 444 ? 74.704  145.734 128.318 1.00 46.92  ? 415 ALA C O     1 
ATOM   6500  C CB    . ALA C 1 444 ? 74.783  147.921 130.794 1.00 46.92  ? 415 ALA C CB    1 
ATOM   6501  N N     . SER C 1 445 ? 76.400  147.203 128.158 1.00 47.54  ? 416 SER C N     1 
ATOM   6502  C CA    . SER C 1 445 ? 76.503  147.031 126.713 1.00 47.54  ? 416 SER C CA    1 
ATOM   6503  C C     . SER C 1 445 ? 76.954  145.620 126.358 1.00 47.54  ? 416 SER C C     1 
ATOM   6504  O O     . SER C 1 445 ? 76.450  145.021 125.398 1.00 47.54  ? 416 SER C O     1 
ATOM   6505  C CB    . SER C 1 445 ? 77.469  148.060 126.128 1.00 47.54  ? 416 SER C CB    1 
ATOM   6506  O OG    . SER C 1 445 ? 77.636  147.865 124.735 1.00 47.54  ? 416 SER C OG    1 
ATOM   6507  N N     . ILE C 1 446 ? 77.893  145.065 127.132 1.00 48.27  ? 417 ILE C N     1 
ATOM   6508  C CA    . ILE C 1 446 ? 78.384  143.715 126.850 1.00 48.27  ? 417 ILE C CA    1 
ATOM   6509  C C     . ILE C 1 446 ? 77.270  142.689 127.038 1.00 48.27  ? 417 ILE C C     1 
ATOM   6510  O O     . ILE C 1 446 ? 77.054  141.827 126.179 1.00 48.27  ? 417 ILE C O     1 
ATOM   6511  C CB    . ILE C 1 446 ? 79.609  143.384 127.725 1.00 48.27  ? 417 ILE C CB    1 
ATOM   6512  C CG1   . ILE C 1 446 ? 80.798  144.323 127.432 1.00 48.27  ? 417 ILE C CG1   1 
ATOM   6513  C CG2   . ILE C 1 446 ? 80.017  141.913 127.557 1.00 48.27  ? 417 ILE C CG2   1 
ATOM   6514  C CD1   . ILE C 1 446 ? 81.383  144.270 126.015 1.00 48.27  ? 417 ILE C CD1   1 
ATOM   6515  N N     . VAL C 1 447 ? 76.537  142.770 128.152 1.00 49.62  ? 418 VAL C N     1 
ATOM   6516  C CA    . VAL C 1 447 ? 75.482  141.788 128.391 1.00 49.62  ? 418 VAL C CA    1 
ATOM   6517  C C     . VAL C 1 447 ? 74.319  142.003 127.427 1.00 49.62  ? 418 VAL C C     1 
ATOM   6518  O O     . VAL C 1 447 ? 73.585  141.057 127.115 1.00 49.62  ? 418 VAL C O     1 
ATOM   6519  C CB    . VAL C 1 447 ? 75.029  141.809 129.868 1.00 49.62  ? 418 VAL C CB    1 
ATOM   6520  C CG1   . VAL C 1 447 ? 73.975  142.879 130.148 1.00 49.62  ? 418 VAL C CG1   1 
ATOM   6521  C CG2   . VAL C 1 447 ? 74.508  140.441 130.275 1.00 49.62  ? 418 VAL C CG2   1 
ATOM   6522  N N     . ALA C 1 448 ? 74.119  143.234 126.946 1.00 52.62  ? 419 ALA C N     1 
ATOM   6523  C CA    . ALA C 1 448 ? 73.165  143.447 125.865 1.00 52.62  ? 419 ALA C CA    1 
ATOM   6524  C C     . ALA C 1 448 ? 73.607  142.725 124.600 1.00 52.62  ? 419 ALA C C     1 
ATOM   6525  O O     . ALA C 1 448 ? 72.783  142.133 123.894 1.00 52.62  ? 419 ALA C O     1 
ATOM   6526  C CB    . ALA C 1 448 ? 72.998  144.941 125.595 1.00 52.62  ? 419 ALA C CB    1 
ATOM   6527  N N     . LYS C 1 449 ? 74.907  142.769 124.294 1.00 52.95  ? 420 LYS C N     1 
ATOM   6528  C CA    . LYS C 1 449 ? 75.409  142.052 123.124 1.00 52.95  ? 420 LYS C CA    1 
ATOM   6529  C C     . LYS C 1 449 ? 75.257  140.542 123.300 1.00 52.95  ? 420 LYS C C     1 
ATOM   6530  O O     . LYS C 1 449 ? 74.944  139.832 122.337 1.00 52.95  ? 420 LYS C O     1 
ATOM   6531  C CB    . LYS C 1 449 ? 76.869  142.433 122.855 1.00 52.95  ? 420 LYS C CB    1 
ATOM   6532  C CG    . LYS C 1 449 ? 77.662  141.439 122.004 1.00 52.95  ? 420 LYS C CG    1 
ATOM   6533  C CD    . LYS C 1 449 ? 78.888  142.096 121.394 1.00 52.95  ? 420 LYS C CD    1 
ATOM   6534  C CE    . LYS C 1 449 ? 79.940  141.066 121.020 1.00 52.95  ? 420 LYS C CE    1 
ATOM   6535  N NZ    . LYS C 1 449 ? 81.101  141.680 120.321 1.00 52.95  ? 420 LYS C NZ    1 
ATOM   6536  N N     . MET C 1 450 ? 75.487  140.032 124.515 1.00 55.21  ? 421 MET C N     1 
ATOM   6537  C CA    . MET C 1 450 ? 75.223  138.618 124.784 1.00 55.21  ? 421 MET C CA    1 
ATOM   6538  C C     . MET C 1 450 ? 73.748  138.281 124.618 1.00 55.21  ? 421 MET C C     1 
ATOM   6539  O O     . MET C 1 450 ? 73.412  137.181 124.166 1.00 55.21  ? 421 MET C O     1 
ATOM   6540  C CB    . MET C 1 450 ? 75.678  138.211 126.194 1.00 55.21  ? 421 MET C CB    1 
ATOM   6541  C CG    . MET C 1 450 ? 77.096  138.597 126.631 1.00 55.21  ? 421 MET C CG    1 
ATOM   6542  S SD    . MET C 1 450 ? 78.243  137.241 126.338 1.00 55.21  ? 421 MET C SD    1 
ATOM   6543  C CE    . MET C 1 450 ? 78.184  136.405 127.920 1.00 55.21  ? 421 MET C CE    1 
ATOM   6544  N N     . ASN C 1 451 ? 72.857  139.204 124.973 1.00 56.93  ? 422 ASN C N     1 
ATOM   6545  C CA    . ASN C 1 451 ? 71.424  138.983 124.825 1.00 56.93  ? 422 ASN C CA    1 
ATOM   6546  C C     . ASN C 1 451 ? 70.936  139.117 123.385 1.00 56.93  ? 422 ASN C C     1 
ATOM   6547  O O     . ASN C 1 451 ? 69.748  138.884 123.136 1.00 56.93  ? 422 ASN C O     1 
ATOM   6548  C CB    . ASN C 1 451 ? 70.651  139.955 125.721 1.00 56.93  ? 422 ASN C CB    1 
ATOM   6549  C CG    . ASN C 1 451 ? 70.787  139.622 127.199 1.00 56.93  ? 422 ASN C CG    1 
ATOM   6550  O OD1   . ASN C 1 451 ? 71.444  138.651 127.573 1.00 56.93  ? 422 ASN C OD1   1 
ATOM   6551  N ND2   . ASN C 1 451 ? 70.156  140.428 128.045 1.00 56.93  ? 422 ASN C ND2   1 
ATOM   6552  N N     . GLY C 1 452 ? 71.800  139.487 122.438 1.00 56.57  ? 423 GLY C N     1 
ATOM   6553  C CA    . GLY C 1 452 ? 71.412  139.536 121.042 1.00 56.57  ? 423 GLY C CA    1 
ATOM   6554  C C     . GLY C 1 452 ? 70.736  140.813 120.603 1.00 56.57  ? 423 GLY C C     1 
ATOM   6555  O O     . GLY C 1 452 ? 70.024  140.800 119.594 1.00 56.57  ? 423 GLY C O     1 
ATOM   6556  N N     . ARG C 1 453 ? 70.927  141.913 121.336 1.00 58.26  ? 424 ARG C N     1 
ATOM   6557  C CA    . ARG C 1 453 ? 70.400  143.222 120.976 1.00 58.26  ? 424 ARG C CA    1 
ATOM   6558  C C     . ARG C 1 453 ? 71.485  144.263 121.201 1.00 58.26  ? 424 ARG C C     1 
ATOM   6559  O O     . ARG C 1 453 ? 72.164  144.250 122.231 1.00 58.26  ? 424 ARG C O     1 
ATOM   6560  C CB    . ARG C 1 453 ? 69.152  143.570 121.796 1.00 58.26  ? 424 ARG C CB    1 
ATOM   6561  C CG    . ARG C 1 453 ? 69.264  143.244 123.277 1.00 58.26  ? 424 ARG C CG    1 
ATOM   6562  C CD    . ARG C 1 453 ? 68.123  143.864 124.061 1.00 58.26  ? 424 ARG C CD    1 
ATOM   6563  N NE    . ARG C 1 453 ? 68.061  143.366 125.434 1.00 58.26  ? 424 ARG C NE    1 
ATOM   6564  C CZ    . ARG C 1 453 ? 67.397  142.290 125.847 1.00 58.26  ? 424 ARG C CZ    1 
ATOM   6565  N NH1   . ARG C 1 453 ? 66.740  141.500 125.009 1.00 58.26  ? 424 ARG C NH1   1 
ATOM   6566  N NH2   . ARG C 1 453 ? 67.400  141.990 127.142 1.00 58.26  ? 424 ARG C NH2   1 
ATOM   6567  N N     . ASP C 1 454 ? 71.642  145.164 120.232 1.00 60.53  ? 425 ASP C N     1 
ATOM   6568  C CA    . ASP C 1 454 ? 72.692  146.172 120.291 1.00 60.53  ? 425 ASP C CA    1 
ATOM   6569  C C     . ASP C 1 454 ? 72.373  147.334 121.228 1.00 60.53  ? 425 ASP C C     1 
ATOM   6570  O O     . ASP C 1 454 ? 73.299  148.060 121.606 1.00 60.53  ? 425 ASP C O     1 
ATOM   6571  C CB    . ASP C 1 454 ? 72.963  146.713 118.881 1.00 60.53  ? 425 ASP C CB    1 
ATOM   6572  C CG    . ASP C 1 454 ? 74.314  147.412 118.754 1.00 60.53  ? 425 ASP C CG    1 
ATOM   6573  O OD1   . ASP C 1 454 ? 75.126  147.381 119.702 1.00 60.53  ? 425 ASP C OD1   1 
ATOM   6574  O OD2   . ASP C 1 454 ? 74.565  148.000 117.681 1.00 60.53  ? 425 ASP C OD2   1 
ATOM   6575  N N     . ASN C 1 455 ? 71.109  147.516 121.621 1.00 57.85  ? 426 ASN C N     1 
ATOM   6576  C CA    . ASN C 1 455 ? 70.671  148.636 122.446 1.00 57.85  ? 426 ASN C CA    1 
ATOM   6577  C C     . ASN C 1 455 ? 70.374  148.160 123.861 1.00 57.85  ? 426 ASN C C     1 
ATOM   6578  O O     . ASN C 1 455 ? 69.721  147.130 124.057 1.00 57.85  ? 426 ASN C O     1 
ATOM   6579  C CB    . ASN C 1 455 ? 69.427  149.295 121.848 1.00 57.85  ? 426 ASN C CB    1 
ATOM   6580  C CG    . ASN C 1 455 ? 69.769  150.310 120.777 1.00 57.85  ? 426 ASN C CG    1 
ATOM   6581  O OD1   . ASN C 1 455 ? 70.764  150.166 120.068 1.00 57.85  ? 426 ASN C OD1   1 
ATOM   6582  N ND2   . ASN C 1 455 ? 68.944  151.343 120.651 1.00 57.85  ? 426 ASN C ND2   1 
ATOM   6583  N N     . ILE C 1 456 ? 70.853  148.923 124.843 1.00 53.09  ? 427 ILE C N     1 
ATOM   6584  C CA    . ILE C 1 456 ? 70.694  148.544 126.241 1.00 53.09  ? 427 ILE C CA    1 
ATOM   6585  C C     . ILE C 1 456 ? 69.229  148.697 126.631 1.00 53.09  ? 427 ILE C C     1 
ATOM   6586  O O     . ILE C 1 456 ? 68.603  149.727 126.352 1.00 53.09  ? 427 ILE C O     1 
ATOM   6587  C CB    . ILE C 1 456 ? 71.620  149.395 127.131 1.00 53.09  ? 427 ILE C CB    1 
ATOM   6588  C CG1   . ILE C 1 456 ? 73.045  148.830 127.070 1.00 53.09  ? 427 ILE C CG1   1 
ATOM   6589  C CG2   . ILE C 1 456 ? 71.145  149.426 128.611 1.00 53.09  ? 427 ILE C CG2   1 
ATOM   6590  C CD1   . ILE C 1 456 ? 74.139  149.781 127.537 1.00 53.09  ? 427 ILE C CD1   1 
ATOM   6591  N N     . CYS C 1 457 ? 68.688  147.675 127.292 1.00 55.70  ? 428 CYS C N     1 
ATOM   6592  C CA    . CYS C 1 457 ? 67.332  147.657 127.828 1.00 55.70  ? 428 CYS C CA    1 
ATOM   6593  C C     . CYS C 1 457 ? 67.381  147.662 129.352 1.00 55.70  ? 428 CYS C C     1 
ATOM   6594  O O     . CYS C 1 457 ? 68.445  147.551 129.964 1.00 55.70  ? 428 CYS C O     1 
ATOM   6595  C CB    . CYS C 1 457 ? 66.567  146.432 127.308 1.00 55.70  ? 428 CYS C CB    1 
ATOM   6596  S SG    . CYS C 1 457 ? 66.208  146.500 125.537 1.00 55.70  ? 428 CYS C SG    1 
ATOM   6597  N N     . LYS C 1 458 ? 66.201  147.810 129.963 1.00 54.31  ? 429 LYS C N     1 
ATOM   6598  C CA    . LYS C 1 458 ? 66.111  147.821 131.420 1.00 54.31  ? 429 LYS C CA    1 
ATOM   6599  C C     . LYS C 1 458 ? 66.538  146.486 132.020 1.00 54.31  ? 429 LYS C C     1 
ATOM   6600  O O     . LYS C 1 458 ? 67.096  146.451 133.125 1.00 54.31  ? 429 LYS C O     1 
ATOM   6601  C CB    . LYS C 1 458 ? 64.683  148.175 131.846 1.00 54.31  ? 429 LYS C CB    1 
ATOM   6602  C CG    . LYS C 1 458 ? 64.426  148.116 133.345 1.00 54.31  ? 429 LYS C CG    1 
ATOM   6603  C CD    . LYS C 1 458 ? 63.152  148.870 133.713 1.00 54.31  ? 429 LYS C CD    1 
ATOM   6604  C CE    . LYS C 1 458 ? 62.402  148.213 134.865 1.00 54.31  ? 429 LYS C CE    1 
ATOM   6605  N NZ    . LYS C 1 458 ? 63.172  148.258 136.137 1.00 54.31  ? 429 LYS C NZ    1 
ATOM   6606  N N     . ALA C 1 459 ? 66.284  145.382 131.311 1.00 55.28  ? 430 ALA C N     1 
ATOM   6607  C CA    . ALA C 1 459 ? 66.719  144.074 131.789 1.00 55.28  ? 430 ALA C CA    1 
ATOM   6608  C C     . ALA C 1 459 ? 68.236  143.986 131.873 1.00 55.28  ? 430 ALA C C     1 
ATOM   6609  O O     . ALA C 1 459 ? 68.768  143.328 132.773 1.00 55.28  ? 430 ALA C O     1 
ATOM   6610  C CB    . ALA C 1 459 ? 66.176  142.975 130.877 1.00 55.28  ? 430 ALA C CB    1 
ATOM   6611  N N     . ASP C 1 460 ? 68.946  144.645 130.955 1.00 52.26  ? 431 ASP C N     1 
ATOM   6612  C CA    . ASP C 1 460 ? 70.405  144.652 131.012 1.00 52.26  ? 431 ASP C CA    1 
ATOM   6613  C C     . ASP C 1 460 ? 70.905  145.358 132.265 1.00 52.26  ? 431 ASP C C     1 
ATOM   6614  O O     . ASP C 1 460 ? 71.829  144.875 132.932 1.00 52.26  ? 431 ASP C O     1 
ATOM   6615  C CB    . ASP C 1 460 ? 70.973  145.324 129.763 1.00 52.26  ? 431 ASP C CB    1 
ATOM   6616  C CG    . ASP C 1 460 ? 70.522  144.654 128.484 1.00 52.26  ? 431 ASP C CG    1 
ATOM   6617  O OD1   . ASP C 1 460 ? 70.608  143.412 128.401 1.00 52.26  ? 431 ASP C OD1   1 
ATOM   6618  O OD2   . ASP C 1 460 ? 70.076  145.370 127.564 1.00 52.26  ? 431 ASP C OD2   1 
ATOM   6619  N N     . ILE C 1 461 ? 70.306  146.503 132.602 1.00 49.72  ? 432 ILE C N     1 
ATOM   6620  C CA    . ILE C 1 461 ? 70.723  147.232 133.795 1.00 49.72  ? 432 ILE C CA    1 
ATOM   6621  C C     . ILE C 1 461 ? 70.380  146.430 135.042 1.00 49.72  ? 432 ILE C C     1 
ATOM   6622  O O     . ILE C 1 461 ? 71.151  146.409 136.008 1.00 49.72  ? 432 ILE C O     1 
ATOM   6623  C CB    . ILE C 1 461 ? 70.085  148.637 133.836 1.00 49.72  ? 432 ILE C CB    1 
ATOM   6624  C CG1   . ILE C 1 461 ? 70.395  149.450 132.561 1.00 49.72  ? 432 ILE C CG1   1 
ATOM   6625  C CG2   . ILE C 1 461 ? 70.556  149.401 135.084 1.00 49.72  ? 432 ILE C CG2   1 
ATOM   6626  C CD1   . ILE C 1 461 ? 71.875  149.638 132.222 1.00 49.72  ? 432 ILE C CD1   1 
ATOM   6627  N N     . GLU C 1 462 ? 69.221  145.763 135.041 1.00 51.59  ? 433 GLU C N     1 
ATOM   6628  C CA    . GLU C 1 462 ? 68.862  144.899 136.163 1.00 51.59  ? 433 GLU C CA    1 
ATOM   6629  C C     . GLU C 1 462 ? 69.871  143.771 136.330 1.00 51.59  ? 433 GLU C C     1 
ATOM   6630  O O     . GLU C 1 462 ? 70.303  143.474 137.451 1.00 51.59  ? 433 GLU C O     1 
ATOM   6631  C CB    . GLU C 1 462 ? 67.458  144.328 135.960 1.00 51.59  ? 433 GLU C CB    1 
ATOM   6632  C CG    . GLU C 1 462 ? 66.330  145.358 136.018 1.00 51.59  ? 433 GLU C CG    1 
ATOM   6633  C CD    . GLU C 1 462 ? 65.829  145.625 137.430 1.00 51.59  ? 433 GLU C CD    1 
ATOM   6634  O OE1   . GLU C 1 462 ? 66.531  145.272 138.402 1.00 51.59  ? 433 GLU C OE1   1 
ATOM   6635  O OE2   . GLU C 1 462 ? 64.724  146.190 137.567 1.00 51.59  ? 433 GLU C OE2   1 
ATOM   6636  N N     . GLU C 1 463 ? 70.293  143.165 135.217 1.00 49.00  ? 434 GLU C N     1 
ATOM   6637  C CA    . GLU C 1 463 ? 71.240  142.058 135.277 1.00 49.00  ? 434 GLU C CA    1 
ATOM   6638  C C     . GLU C 1 463 ? 72.596  142.519 135.798 1.00 49.00  ? 434 GLU C C     1 
ATOM   6639  O O     . GLU C 1 463 ? 73.154  141.904 136.714 1.00 49.00  ? 434 GLU C O     1 
ATOM   6640  C CB    . GLU C 1 463 ? 71.372  141.422 133.887 1.00 49.00  ? 434 GLU C CB    1 
ATOM   6641  C CG    . GLU C 1 463 ? 72.202  140.130 133.799 1.00 49.00  ? 434 GLU C CG    1 
ATOM   6642  C CD    . GLU C 1 463 ? 71.482  138.909 134.350 1.00 49.00  ? 434 GLU C CD    1 
ATOM   6643  O OE1   . GLU C 1 463 ? 70.479  139.065 135.077 1.00 49.00  ? 434 GLU C OE1   1 
ATOM   6644  O OE2   . GLU C 1 463 ? 71.925  137.782 134.051 1.00 49.00  ? 434 GLU C OE2   1 
ATOM   6645  N N     . VAL C 1 464 ? 73.141  143.603 135.237 1.00 45.06  ? 435 VAL C N     1 
ATOM   6646  C CA    . VAL C 1 464 ? 74.474  144.033 135.663 1.00 45.06  ? 435 VAL C CA    1 
ATOM   6647  C C     . VAL C 1 464 ? 74.443  144.578 137.087 1.00 45.06  ? 435 VAL C C     1 
ATOM   6648  O O     . VAL C 1 464 ? 75.424  144.436 137.826 1.00 45.06  ? 435 VAL C O     1 
ATOM   6649  C CB    . VAL C 1 464 ? 75.093  145.057 134.690 1.00 45.06  ? 435 VAL C CB    1 
ATOM   6650  C CG1   . VAL C 1 464 ? 75.179  144.482 133.288 1.00 45.06  ? 435 VAL C CG1   1 
ATOM   6651  C CG2   . VAL C 1 464 ? 74.346  146.383 134.706 1.00 45.06  ? 435 VAL C CG2   1 
ATOM   6652  N N     . THR C 1 465 ? 73.337  145.201 137.506 1.00 46.32  ? 436 THR C N     1 
ATOM   6653  C CA    . THR C 1 465 ? 73.229  145.629 138.895 1.00 46.32  ? 436 THR C CA    1 
ATOM   6654  C C     . THR C 1 465 ? 73.149  144.432 139.831 1.00 46.32  ? 436 THR C C     1 
ATOM   6655  O O     . THR C 1 465 ? 73.679  144.474 140.947 1.00 46.32  ? 436 THR C O     1 
ATOM   6656  C CB    . THR C 1 465 ? 72.009  146.527 139.071 1.00 46.32  ? 436 THR C CB    1 
ATOM   6657  O OG1   . THR C 1 465 ? 72.139  147.673 138.225 1.00 46.32  ? 436 THR C OG1   1 
ATOM   6658  C CG2   . THR C 1 465 ? 71.879  146.980 140.519 1.00 46.32  ? 436 THR C CG2   1 
ATOM   6659  N N     . SER C 1 466 ? 72.477  143.361 139.403 1.00 48.63  ? 437 SER C N     1 
ATOM   6660  C CA    . SER C 1 466 ? 72.454  142.143 140.203 1.00 48.63  ? 437 SER C CA    1 
ATOM   6661  C C     . SER C 1 466 ? 73.842  141.524 140.304 1.00 48.63  ? 437 SER C C     1 
ATOM   6662  O O     . SER C 1 466 ? 74.233  141.031 141.368 1.00 48.63  ? 437 SER C O     1 
ATOM   6663  C CB    . SER C 1 466 ? 71.464  141.145 139.603 1.00 48.63  ? 437 SER C CB    1 
ATOM   6664  O OG    . SER C 1 466 ? 71.259  140.044 140.471 1.00 48.63  ? 437 SER C OG    1 
ATOM   6665  N N     . LEU C 1 467 ? 74.605  141.547 139.210 1.00 45.93  ? 438 LEU C N     1 
ATOM   6666  C CA    . LEU C 1 467 ? 75.907  140.887 139.202 1.00 45.93  ? 438 LEU C CA    1 
ATOM   6667  C C     . LEU C 1 467 ? 76.932  141.673 140.012 1.00 45.93  ? 438 LEU C C     1 
ATOM   6668  O O     . LEU C 1 467 ? 77.471  141.173 141.005 1.00 45.93  ? 438 LEU C O     1 
ATOM   6669  C CB    . LEU C 1 467 ? 76.395  140.702 137.762 1.00 45.93  ? 438 LEU C CB    1 
ATOM   6670  C CG    . LEU C 1 467 ? 75.659  139.702 136.863 1.00 45.93  ? 438 LEU C CG    1 
ATOM   6671  C CD1   . LEU C 1 467 ? 76.196  139.790 135.441 1.00 45.93  ? 438 LEU C CD1   1 
ATOM   6672  C CD2   . LEU C 1 467 ? 75.760  138.279 137.387 1.00 45.93  ? 438 LEU C CD2   1 
ATOM   6673  N N     . TYR C 1 468 ? 77.203  142.914 139.607 1.00 44.08  ? 439 TYR C N     1 
ATOM   6674  C CA    . TYR C 1 468 ? 78.322  143.694 140.123 1.00 44.08  ? 439 TYR C CA    1 
ATOM   6675  C C     . TYR C 1 468 ? 77.823  144.630 141.216 1.00 44.08  ? 439 TYR C C     1 
ATOM   6676  O O     . TYR C 1 468 ? 77.041  145.546 140.941 1.00 44.08  ? 439 TYR C O     1 
ATOM   6677  C CB    . TYR C 1 468 ? 78.973  144.500 138.998 1.00 44.08  ? 439 TYR C CB    1 
ATOM   6678  C CG    . TYR C 1 468 ? 79.434  143.665 137.825 1.00 44.08  ? 439 TYR C CG    1 
ATOM   6679  C CD1   . TYR C 1 468 ? 80.208  142.529 138.007 1.00 44.08  ? 439 TYR C CD1   1 
ATOM   6680  C CD2   . TYR C 1 468 ? 79.089  144.019 136.529 1.00 44.08  ? 439 TYR C CD2   1 
ATOM   6681  C CE1   . TYR C 1 468 ? 80.621  141.772 136.937 1.00 44.08  ? 439 TYR C CE1   1 
ATOM   6682  C CE2   . TYR C 1 468 ? 79.497  143.267 135.454 1.00 44.08  ? 439 TYR C CE2   1 
ATOM   6683  C CZ    . TYR C 1 468 ? 80.262  142.145 135.664 1.00 44.08  ? 439 TYR C CZ    1 
ATOM   6684  O OH    . TYR C 1 468 ? 80.669  141.395 134.590 1.00 44.08  ? 439 TYR C OH    1 
ATOM   6685  N N     . LEU C 1 469 ? 78.291  144.408 142.441 1.00 48.72  ? 440 LEU C N     1 
ATOM   6686  C CA    . LEU C 1 469 ? 77.917  145.216 143.592 1.00 48.72  ? 440 LEU C CA    1 
ATOM   6687  C C     . LEU C 1 469 ? 78.936  146.326 143.825 1.00 48.72  ? 440 LEU C C     1 
ATOM   6688  O O     . LEU C 1 469 ? 80.089  146.248 143.396 1.00 48.72  ? 440 LEU C O     1 
ATOM   6689  C CB    . LEU C 1 469 ? 77.811  144.348 144.846 1.00 48.72  ? 440 LEU C CB    1 
ATOM   6690  C CG    . LEU C 1 469 ? 76.817  143.186 144.813 1.00 48.72  ? 440 LEU C CG    1 
ATOM   6691  C CD1   . LEU C 1 469 ? 76.968  142.338 146.065 1.00 48.72  ? 440 LEU C CD1   1 
ATOM   6692  C CD2   . LEU C 1 469 ? 75.385  143.685 144.677 1.00 48.72  ? 440 LEU C CD2   1 
ATOM   6693  N N     . ASP C 1 470 ? 78.486  147.372 144.510 1.00 49.58  ? 441 ASP C N     1 
ATOM   6694  C CA    . ASP C 1 470 ? 79.390  148.413 144.970 1.00 49.58  ? 441 ASP C CA    1 
ATOM   6695  C C     . ASP C 1 470 ? 80.198  147.910 146.165 1.00 49.58  ? 441 ASP C C     1 
ATOM   6696  O O     . ASP C 1 470 ? 79.929  146.846 146.729 1.00 49.58  ? 441 ASP C O     1 
ATOM   6697  C CB    . ASP C 1 470 ? 78.615  149.675 145.346 1.00 49.58  ? 441 ASP C CB    1 
ATOM   6698  C CG    . ASP C 1 470 ? 77.662  149.450 146.499 1.00 49.58  ? 441 ASP C CG    1 
ATOM   6699  O OD1   . ASP C 1 470 ? 76.526  148.998 146.254 1.00 49.58  ? 441 ASP C OD1   1 
ATOM   6700  O OD2   . ASP C 1 470 ? 78.054  149.717 147.653 1.00 49.58  ? 441 ASP C OD2   1 
ATOM   6701  N N     . ALA C 1 471 ? 81.211  148.691 146.545 1.00 50.35  ? 442 ALA C N     1 
ATOM   6702  C CA    . ALA C 1 471 ? 82.112  148.269 147.614 1.00 50.35  ? 442 ALA C CA    1 
ATOM   6703  C C     . ALA C 1 471 ? 81.401  148.206 148.961 1.00 50.35  ? 442 ALA C C     1 
ATOM   6704  O O     . ALA C 1 471 ? 81.611  147.262 149.733 1.00 50.35  ? 442 ALA C O     1 
ATOM   6705  C CB    . ALA C 1 471 ? 83.310  149.213 147.688 1.00 50.35  ? 442 ALA C CB    1 
ATOM   6706  N N     . LYS C 1 472 ? 80.560  149.200 149.261 1.00 53.80  ? 443 LYS C N     1 
ATOM   6707  C CA    . LYS C 1 472 ? 79.858  149.221 150.541 1.00 53.80  ? 443 LYS C CA    1 
ATOM   6708  C C     . LYS C 1 472 ? 78.884  148.055 150.652 1.00 53.80  ? 443 LYS C C     1 
ATOM   6709  O O     . LYS C 1 472 ? 78.869  147.341 151.662 1.00 53.80  ? 443 LYS C O     1 
ATOM   6710  C CB    . LYS C 1 472 ? 79.119  150.549 150.716 1.00 53.80  ? 443 LYS C CB    1 
ATOM   6711  C CG    . LYS C 1 472 ? 80.032  151.769 150.814 1.00 53.80  ? 443 LYS C CG    1 
ATOM   6712  C CD    . LYS C 1 472 ? 79.373  152.957 151.526 1.00 53.80  ? 443 LYS C CD    1 
ATOM   6713  C CE    . LYS C 1 472 ? 78.299  153.633 150.677 1.00 53.80  ? 443 LYS C CE    1 
ATOM   6714  N NZ    . LYS C 1 472 ? 78.887  154.544 149.657 1.00 53.80  ? 443 LYS C NZ    1 
ATOM   6715  N N     . SER C 1 473 ? 78.075  147.837 149.613 1.00 53.29  ? 444 SER C N     1 
ATOM   6716  C CA    . SER C 1 473 ? 77.119  146.734 149.633 1.00 53.29  ? 444 SER C CA    1 
ATOM   6717  C C     . SER C 1 473 ? 77.829  145.387 149.626 1.00 53.29  ? 444 SER C C     1 
ATOM   6718  O O     . SER C 1 473 ? 77.372  144.437 150.272 1.00 53.29  ? 444 SER C O     1 
ATOM   6719  C CB    . SER C 1 473 ? 76.171  146.843 148.440 1.00 53.29  ? 444 SER C CB    1 
ATOM   6720  O OG    . SER C 1 473 ? 75.439  148.055 148.481 1.00 53.29  ? 444 SER C OG    1 
ATOM   6721  N N     . SER C 1 474 ? 78.945  145.284 148.901 1.00 52.23  ? 445 SER C N     1 
ATOM   6722  C CA    . SER C 1 474 ? 79.695  144.032 148.864 1.00 52.23  ? 445 SER C CA    1 
ATOM   6723  C C     . SER C 1 474 ? 80.269  143.695 150.235 1.00 52.23  ? 445 SER C C     1 
ATOM   6724  O O     . SER C 1 474 ? 80.165  142.554 150.700 1.00 52.23  ? 445 SER C O     1 
ATOM   6725  C CB    . SER C 1 474 ? 80.807  144.123 147.822 1.00 52.23  ? 445 SER C CB    1 
ATOM   6726  O OG    . SER C 1 474 ? 81.655  142.991 147.879 1.00 52.23  ? 445 SER C OG    1 
ATOM   6727  N N     . ALA C 1 475 ? 80.866  144.683 150.907 1.00 55.74  ? 446 ALA C N     1 
ATOM   6728  C CA    . ALA C 1 475 ? 81.378  144.445 152.253 1.00 55.74  ? 446 ALA C CA    1 
ATOM   6729  C C     . ALA C 1 475 ? 80.252  144.163 153.238 1.00 55.74  ? 446 ALA C C     1 
ATOM   6730  O O     . ALA C 1 475 ? 80.429  143.363 154.168 1.00 55.74  ? 446 ALA C O     1 
ATOM   6731  C CB    . ALA C 1 475 ? 82.202  145.641 152.722 1.00 55.74  ? 446 ALA C CB    1 
ATOM   6732  N N     . LYS C 1 476 ? 79.096  144.808 153.053 1.00 58.51  ? 447 LYS C N     1 
ATOM   6733  C CA    . LYS C 1 476 ? 77.953  144.553 153.920 1.00 58.51  ? 447 LYS C CA    1 
ATOM   6734  C C     . LYS C 1 476 ? 77.482  143.111 153.786 1.00 58.51  ? 447 LYS C C     1 
ATOM   6735  O O     . LYS C 1 476 ? 77.265  142.416 154.788 1.00 58.51  ? 447 LYS C O     1 
ATOM   6736  C CB    . LYS C 1 476 ? 76.826  145.530 153.585 1.00 58.51  ? 447 LYS C CB    1 
ATOM   6737  C CG    . LYS C 1 476 ? 75.752  145.629 154.660 1.00 58.51  ? 447 LYS C CG    1 
ATOM   6738  C CD    . LYS C 1 476 ? 74.674  146.656 154.319 1.00 58.51  ? 447 LYS C CD    1 
ATOM   6739  C CE    . LYS C 1 476 ? 75.166  148.093 154.485 1.00 58.51  ? 447 LYS C CE    1 
ATOM   6740  N NZ    . LYS C 1 476 ? 74.081  149.089 154.270 1.00 58.51  ? 447 LYS C NZ    1 
ATOM   6741  N N     . LEU C 1 477 ? 77.355  142.634 152.545 1.00 57.93  ? 448 LEU C N     1 
ATOM   6742  C CA    . LEU C 1 477 ? 76.971  141.248 152.312 1.00 57.93  ? 448 LEU C CA    1 
ATOM   6743  C C     . LEU C 1 477 ? 78.034  140.287 152.822 1.00 57.93  ? 448 LEU C C     1 
ATOM   6744  O O     . LEU C 1 477 ? 77.703  139.189 153.281 1.00 57.93  ? 448 LEU C O     1 
ATOM   6745  C CB    . LEU C 1 477 ? 76.701  141.026 150.819 1.00 57.93  ? 448 LEU C CB    1 
ATOM   6746  C CG    . LEU C 1 477 ? 76.226  139.646 150.319 1.00 57.93  ? 448 LEU C CG    1 
ATOM   6747  C CD1   . LEU C 1 477 ? 75.375  139.818 149.056 1.00 57.93  ? 448 LEU C CD1   1 
ATOM   6748  C CD2   . LEU C 1 477 ? 77.375  138.648 150.041 1.00 57.93  ? 448 LEU C CD2   1 
ATOM   6749  N N     . LEU C 1 478 ? 79.309  140.671 152.744 1.00 57.07  ? 449 LEU C N     1 
ATOM   6750  C CA    . LEU C 1 478 ? 80.362  139.790 153.242 1.00 57.07  ? 449 LEU C CA    1 
ATOM   6751  C C     . LEU C 1 478 ? 80.280  139.631 154.755 1.00 57.07  ? 449 LEU C C     1 
ATOM   6752  O O     . LEU C 1 478 ? 80.323  138.507 155.267 1.00 57.07  ? 449 LEU C O     1 
ATOM   6753  C CB    . LEU C 1 478 ? 81.749  140.302 152.836 1.00 57.07  ? 449 LEU C CB    1 
ATOM   6754  C CG    . LEU C 1 478 ? 82.474  139.487 151.759 1.00 57.07  ? 449 LEU C CG    1 
ATOM   6755  C CD1   . LEU C 1 478 ? 83.721  140.215 151.283 1.00 57.07  ? 449 LEU C CD1   1 
ATOM   6756  C CD2   . LEU C 1 478 ? 82.856  138.095 152.265 1.00 57.07  ? 449 LEU C CD2   1 
ATOM   6757  N N     . HIS C 1 479 ? 80.151  140.740 155.493 1.00 63.19  ? 450 HIS C N     1 
ATOM   6758  C CA    . HIS C 1 479 ? 80.174  140.614 156.948 1.00 63.19  ? 450 HIS C CA    1 
ATOM   6759  C C     . HIS C 1 479 ? 78.858  140.051 157.481 1.00 63.19  ? 450 HIS C C     1 
ATOM   6760  O O     . HIS C 1 479 ? 78.862  139.383 158.520 1.00 63.19  ? 450 HIS C O     1 
ATOM   6761  C CB    . HIS C 1 479 ? 80.497  141.958 157.623 1.00 63.19  ? 450 HIS C CB    1 
ATOM   6762  C CG    . HIS C 1 479 ? 79.296  142.754 158.035 1.00 63.19  ? 450 HIS C CG    1 
ATOM   6763  N ND1   . HIS C 1 479 ? 78.603  143.565 157.166 1.00 63.19  ? 450 HIS C ND1   1 
ATOM   6764  C CD2   . HIS C 1 479 ? 78.685  142.885 159.237 1.00 63.19  ? 450 HIS C CD2   1 
ATOM   6765  C CE1   . HIS C 1 479 ? 77.604  144.145 157.806 1.00 63.19  ? 450 HIS C CE1   1 
ATOM   6766  N NE2   . HIS C 1 479 ? 77.631  143.749 159.065 1.00 63.19  ? 450 HIS C NE2   1 
ATOM   6767  N N     . GLU C 1 480 ? 77.730  140.291 156.794 1.00 66.48  ? 451 GLU C N     1 
ATOM   6768  C CA    . GLU C 1 480 ? 76.450  139.821 157.317 1.00 66.48  ? 451 GLU C CA    1 
ATOM   6769  C C     . GLU C 1 480 ? 76.263  138.321 157.115 1.00 66.48  ? 451 GLU C C     1 
ATOM   6770  O O     . GLU C 1 480 ? 75.657  137.664 157.970 1.00 66.48  ? 451 GLU C O     1 
ATOM   6771  C CB    . GLU C 1 480 ? 75.293  140.612 156.687 1.00 66.48  ? 451 GLU C CB    1 
ATOM   6772  C CG    . GLU C 1 480 ? 74.678  140.043 155.403 1.00 66.48  ? 451 GLU C CG    1 
ATOM   6773  C CD    . GLU C 1 480 ? 73.812  141.056 154.682 1.00 66.48  ? 451 GLU C CD    1 
ATOM   6774  O OE1   . GLU C 1 480 ? 73.230  141.928 155.360 1.00 66.48  ? 451 GLU C OE1   1 
ATOM   6775  O OE2   . GLU C 1 480 ? 73.697  140.973 153.442 1.00 66.48  ? 451 GLU C OE2   1 
ATOM   6776  N N     . GLN C 1 481 ? 76.778  137.770 156.014 1.00 64.16  ? 452 GLN C N     1 
ATOM   6777  C CA    . GLN C 1 481 ? 76.608  136.357 155.668 1.00 64.16  ? 452 GLN C CA    1 
ATOM   6778  C C     . GLN C 1 481 ? 77.917  135.631 155.970 1.00 64.16  ? 452 GLN C C     1 
ATOM   6779  O O     . GLN C 1 481 ? 78.997  136.111 155.632 1.00 64.16  ? 452 GLN C O     1 
ATOM   6780  C CB    . GLN C 1 481 ? 76.157  136.232 154.191 1.00 64.16  ? 452 GLN C CB    1 
ATOM   6781  C CG    . GLN C 1 481 ? 76.664  135.053 153.321 1.00 64.16  ? 452 GLN C CG    1 
ATOM   6782  C CD    . GLN C 1 481 ? 76.347  135.257 151.852 1.00 64.16  ? 452 GLN C CD    1 
ATOM   6783  O OE1   . GLN C 1 481 ? 77.205  135.674 151.073 1.00 64.16  ? 452 GLN C OE1   1 
ATOM   6784  N NE2   . GLN C 1 481 ? 75.111  134.963 151.465 1.00 64.16  ? 452 GLN C NE2   1 
ATOM   6785  N N     . ILE D 1 47  ? 111.704 114.717 176.757 1.00 29.58  ? 18  ILE B N     1 
ATOM   6786  C CA    . ILE D 1 47  ? 110.285 114.364 177.044 1.00 29.58  ? 18  ILE B CA    1 
ATOM   6787  C C     . ILE D 1 47  ? 110.228 113.121 177.929 1.00 29.58  ? 18  ILE B C     1 
ATOM   6788  O O     . ILE D 1 47  ? 109.670 112.095 177.545 1.00 29.58  ? 18  ILE B O     1 
ATOM   6789  C CB    . ILE D 1 47  ? 109.483 114.164 175.735 1.00 29.58  ? 18  ILE B CB    1 
ATOM   6790  C CG1   . ILE D 1 47  ? 110.229 113.248 174.756 1.00 29.58  ? 18  ILE B CG1   1 
ATOM   6791  C CG2   . ILE D 1 47  ? 109.196 115.507 175.080 1.00 29.58  ? 18  ILE B CG2   1 
ATOM   6792  C CD1   . ILE D 1 47  ? 109.314 112.471 173.845 1.00 29.58  ? 18  ILE B CD1   1 
ATOM   6793  N N     . ALA D 1 48  ? 110.825 113.219 179.117 1.00 29.96  ? 19  ALA B N     1 
ATOM   6794  C CA    . ALA D 1 48  ? 110.833 112.092 180.041 1.00 29.96  ? 19  ALA B CA    1 
ATOM   6795  C C     . ALA D 1 48  ? 109.455 111.792 180.615 1.00 29.96  ? 19  ALA B C     1 
ATOM   6796  O O     . ALA D 1 48  ? 109.221 110.664 181.063 1.00 29.96  ? 19  ALA B O     1 
ATOM   6797  C CB    . ALA D 1 48  ? 111.815 112.359 181.181 1.00 29.96  ? 19  ALA B CB    1 
ATOM   6798  N N     . THR D 1 49  ? 108.546 112.771 180.629 1.00 29.80  ? 20  THR B N     1 
ATOM   6799  C CA    . THR D 1 49  ? 107.229 112.549 181.221 1.00 29.80  ? 20  THR B CA    1 
ATOM   6800  C C     . THR D 1 49  ? 106.413 111.532 180.425 1.00 29.80  ? 20  THR B C     1 
ATOM   6801  O O     . THR D 1 49  ? 105.658 110.748 181.012 1.00 29.80  ? 20  THR B O     1 
ATOM   6802  C CB    . THR D 1 49  ? 106.476 113.882 181.362 1.00 29.80  ? 20  THR B CB    1 
ATOM   6803  O OG1   . THR D 1 49  ? 105.217 113.654 182.004 1.00 29.80  ? 20  THR B OG1   1 
ATOM   6804  C CG2   . THR D 1 49  ? 106.236 114.585 180.014 1.00 29.80  ? 20  THR B CG2   1 
ATOM   6805  N N     . HIS D 1 50  ? 106.556 111.518 179.094 1.00 30.02  ? 21  HIS B N     1 
ATOM   6806  C CA    . HIS D 1 50  ? 105.851 110.578 178.224 1.00 30.02  ? 21  HIS B CA    1 
ATOM   6807  C C     . HIS D 1 50  ? 106.640 109.299 177.968 1.00 30.02  ? 21  HIS B C     1 
ATOM   6808  O O     . HIS D 1 50  ? 106.466 108.674 176.914 1.00 30.02  ? 21  HIS B O     1 
ATOM   6809  C CB    . HIS D 1 50  ? 105.507 111.238 176.888 1.00 30.02  ? 21  HIS B CB    1 
ATOM   6810  C CG    . HIS D 1 50  ? 104.769 112.532 177.013 1.00 30.02  ? 21  HIS B CG    1 
ATOM   6811  N ND1   . HIS D 1 50  ? 105.350 113.751 176.743 1.00 30.02  ? 21  HIS B ND1   1 
ATOM   6812  C CD2   . HIS D 1 50  ? 103.487 112.794 177.355 1.00 30.02  ? 21  HIS B CD2   1 
ATOM   6813  C CE1   . HIS D 1 50  ? 104.461 114.710 176.924 1.00 30.02  ? 21  HIS B CE1   1 
ATOM   6814  N NE2   . HIS D 1 50  ? 103.323 114.156 177.301 1.00 30.02  ? 21  HIS B NE2   1 
ATOM   6815  N N     . THR D 1 51  ? 107.511 108.893 178.892 1.00 31.63  ? 22  THR B N     1 
ATOM   6816  C CA    . THR D 1 51  ? 108.307 107.690 178.668 1.00 31.63  ? 22  THR B CA    1 
ATOM   6817  C C     . THR D 1 51  ? 107.446 106.432 178.684 1.00 31.63  ? 22  THR B C     1 
ATOM   6818  O O     . THR D 1 51  ? 107.750 105.468 177.974 1.00 31.63  ? 22  THR B O     1 
ATOM   6819  C CB    . THR D 1 51  ? 109.412 107.595 179.723 1.00 31.63  ? 22  THR B CB    1 
ATOM   6820  O OG1   . THR D 1 51  ? 110.329 108.683 179.554 1.00 31.63  ? 22  THR B OG1   1 
ATOM   6821  C CG2   . THR D 1 51  ? 110.180 106.278 179.608 1.00 31.63  ? 22  THR B CG2   1 
ATOM   6822  N N     . HIS D 1 52  ? 106.374 106.419 179.476 1.00 33.32  ? 23  HIS B N     1 
ATOM   6823  C CA    . HIS D 1 52  ? 105.572 105.211 179.623 1.00 33.32  ? 23  HIS B CA    1 
ATOM   6824  C C     . HIS D 1 52  ? 104.722 104.900 178.397 1.00 33.32  ? 23  HIS B C     1 
ATOM   6825  O O     . HIS D 1 52  ? 104.297 103.751 178.238 1.00 33.32  ? 23  HIS B O     1 
ATOM   6826  C CB    . HIS D 1 52  ? 104.675 105.336 180.853 1.00 33.32  ? 23  HIS B CB    1 
ATOM   6827  C CG    . HIS D 1 52  ? 103.505 106.245 180.660 1.00 33.32  ? 23  HIS B CG    1 
ATOM   6828  N ND1   . HIS D 1 52  ? 103.639 107.607 180.509 1.00 33.32  ? 23  HIS B ND1   1 
ATOM   6829  C CD2   . HIS D 1 52  ? 102.178 105.988 180.602 1.00 33.32  ? 23  HIS B CD2   1 
ATOM   6830  C CE1   . HIS D 1 52  ? 102.445 108.150 180.364 1.00 33.32  ? 23  HIS B CE1   1 
ATOM   6831  N NE2   . HIS D 1 52  ? 101.542 107.189 180.415 1.00 33.32  ? 23  HIS B NE2   1 
ATOM   6832  N N     . ILE D 1 53  ? 104.461 105.877 177.534 1.00 32.36  ? 24  ILE B N     1 
ATOM   6833  C CA    . ILE D 1 53  ? 103.635 105.648 176.352 1.00 32.36  ? 24  ILE B CA    1 
ATOM   6834  C C     . ILE D 1 53  ? 104.458 104.896 175.317 1.00 32.36  ? 24  ILE B C     1 
ATOM   6835  O O     . ILE D 1 53  ? 105.609 105.256 175.041 1.00 32.36  ? 24  ILE B O     1 
ATOM   6836  C CB    . ILE D 1 53  ? 103.102 106.979 175.795 1.00 32.36  ? 24  ILE B CB    1 
ATOM   6837  C CG1   . ILE D 1 53  ? 102.012 107.532 176.712 1.00 32.36  ? 24  ILE B CG1   1 
ATOM   6838  C CG2   . ILE D 1 53  ? 102.530 106.814 174.382 1.00 32.36  ? 24  ILE B CG2   1 
ATOM   6839  C CD1   . ILE D 1 53  ? 101.912 109.026 176.684 1.00 32.36  ? 24  ILE B CD1   1 
ATOM   6840  N N     . LYS D 1 54  ? 103.859 103.845 174.743 1.00 34.73  ? 25  LYS B N     1 
ATOM   6841  C CA    . LYS D 1 54  ? 104.483 103.013 173.722 1.00 34.73  ? 25  LYS B CA    1 
ATOM   6842  C C     . LYS D 1 54  ? 103.626 102.830 172.474 1.00 34.73  ? 25  LYS B C     1 
ATOM   6843  O O     . LYS D 1 54  ? 104.073 102.158 171.539 1.00 34.73  ? 25  LYS B O     1 
ATOM   6844  C CB    . LYS D 1 54  ? 104.821 101.630 174.302 1.00 34.73  ? 25  LYS B CB    1 
ATOM   6845  C CG    . LYS D 1 54  ? 105.807 101.659 175.467 1.00 34.73  ? 25  LYS B CG    1 
ATOM   6846  C CD    . LYS D 1 54  ? 105.947 100.293 176.119 1.00 34.73  ? 25  LYS B CD    1 
ATOM   6847  C CE    . LYS D 1 54  ? 106.762 100.368 177.402 1.00 34.73  ? 25  LYS B CE    1 
ATOM   6848  N NZ    . LYS D 1 54  ? 108.195 100.670 177.137 1.00 34.73  ? 25  LYS B NZ    1 
ATOM   6849  N N     . GLY D 1 55  ? 102.430 103.399 172.425 1.00 32.14  ? 26  GLY B N     1 
ATOM   6850  C CA    . GLY D 1 55  ? 101.569 103.262 171.269 1.00 32.14  ? 26  GLY B CA    1 
ATOM   6851  C C     . GLY D 1 55  ? 100.142 103.591 171.633 1.00 32.14  ? 26  GLY B C     1 
ATOM   6852  O O     . GLY D 1 55  ? 99.792  103.754 172.801 1.00 32.14  ? 26  GLY B O     1 
ATOM   6853  N N     . LEU D 1 56  ? 99.309  103.691 170.596 1.00 32.64  ? 27  LEU B N     1 
ATOM   6854  C CA    . LEU D 1 56  ? 97.893  103.964 170.825 1.00 32.64  ? 27  LEU B CA    1 
ATOM   6855  C C     . LEU D 1 56  ? 97.208  102.817 171.554 1.00 32.64  ? 27  LEU B C     1 
ATOM   6856  O O     . LEU D 1 56  ? 96.258  103.048 172.310 1.00 32.64  ? 27  LEU B O     1 
ATOM   6857  C CB    . LEU D 1 56  ? 97.169  104.242 169.506 1.00 32.64  ? 27  LEU B CB    1 
ATOM   6858  C CG    . LEU D 1 56  ? 96.883  105.702 169.137 1.00 32.64  ? 27  LEU B CG    1 
ATOM   6859  C CD1   . LEU D 1 56  ? 98.144  106.537 169.032 1.00 32.64  ? 27  LEU B CD1   1 
ATOM   6860  C CD2   . LEU D 1 56  ? 96.089  105.763 167.836 1.00 32.64  ? 27  LEU B CD2   1 
ATOM   6861  N N     . GLY D 1 57  ? 97.662  101.585 171.342 1.00 35.72  ? 28  GLY B N     1 
ATOM   6862  C CA    . GLY D 1 57  ? 97.074  100.450 172.022 1.00 35.72  ? 28  GLY B CA    1 
ATOM   6863  C C     . GLY D 1 57  ? 95.669  100.162 171.541 1.00 35.72  ? 28  GLY B C     1 
ATOM   6864  O O     . GLY D 1 57  ? 94.702  100.355 172.285 1.00 35.72  ? 28  GLY B O     1 
ATOM   6865  N N     . LEU D 1 58  ? 95.554  99.705  170.297 1.00 38.43  ? 29  LEU B N     1 
ATOM   6866  C CA    . LEU D 1 58  ? 94.289  99.440  169.630 1.00 38.43  ? 29  LEU B CA    1 
ATOM   6867  C C     . LEU D 1 58  ? 94.144  97.951  169.351 1.00 38.43  ? 29  LEU B C     1 
ATOM   6868  O O     . LEU D 1 58  ? 95.129  97.220  169.219 1.00 38.43  ? 29  LEU B O     1 
ATOM   6869  C CB    . LEU D 1 58  ? 94.200  100.215 168.313 1.00 38.43  ? 29  LEU B CB    1 
ATOM   6870  C CG    . LEU D 1 58  ? 94.191  101.742 168.428 1.00 38.43  ? 29  LEU B CG    1 
ATOM   6871  C CD1   . LEU D 1 58  ? 94.331  102.396 167.067 1.00 38.43  ? 29  LEU B CD1   1 
ATOM   6872  C CD2   . LEU D 1 58  ? 92.942  102.261 169.129 1.00 38.43  ? 29  LEU B CD2   1 
ATOM   6873  N N     . GLU D 1 59  ? 92.892  97.510  169.261 1.00 43.97  ? 30  GLU B N     1 
ATOM   6874  C CA    . GLU D 1 59  ? 92.596  96.154  168.847 1.00 43.97  ? 30  GLU B CA    1 
ATOM   6875  C C     . GLU D 1 59  ? 92.847  96.031  167.344 1.00 43.97  ? 30  GLU B C     1 
ATOM   6876  O O     . GLU D 1 59  ? 93.067  97.038  166.666 1.00 43.97  ? 30  GLU B O     1 
ATOM   6877  C CB    . GLU D 1 59  ? 91.151  95.797  169.189 1.00 43.97  ? 30  GLU B CB    1 
ATOM   6878  C CG    . GLU D 1 59  ? 90.917  95.504  170.661 1.00 43.97  ? 30  GLU B CG    1 
ATOM   6879  C CD    . GLU D 1 59  ? 89.462  95.207  170.971 1.00 43.97  ? 30  GLU B CD    1 
ATOM   6880  O OE1   . GLU D 1 59  ? 88.814  94.503  170.169 1.00 43.97  ? 30  GLU B OE1   1 
ATOM   6881  O OE2   . GLU D 1 59  ? 88.967  95.680  172.015 1.00 43.97  ? 30  GLU B OE2   1 
ATOM   6882  N N     . PRO D 1 60  ? 92.867  94.806  166.795 1.00 44.69  ? 31  PRO B N     1 
ATOM   6883  C CA    . PRO D 1 60  ? 92.905  94.684  165.324 1.00 44.69  ? 31  PRO B CA    1 
ATOM   6884  C C     . PRO D 1 60  ? 91.721  95.346  164.639 1.00 44.69  ? 31  PRO B C     1 
ATOM   6885  O O     . PRO D 1 60  ? 91.874  95.909  163.548 1.00 44.69  ? 31  PRO B O     1 
ATOM   6886  C CB    . PRO D 1 60  ? 92.912  93.168  165.080 1.00 44.69  ? 31  PRO B CB    1 
ATOM   6887  C CG    . PRO D 1 60  ? 93.160  92.518  166.379 1.00 44.69  ? 31  PRO B CG    1 
ATOM   6888  C CD    . PRO D 1 60  ? 93.162  93.529  167.471 1.00 44.69  ? 31  PRO B CD    1 
ATOM   6889  N N     . THR D 1 61  ? 90.540  95.300  165.259 1.00 46.28  ? 32  THR B N     1 
ATOM   6890  C CA    . THR D 1 61  ? 89.371  95.988  164.719 1.00 46.28  ? 32  THR B CA    1 
ATOM   6891  C C     . THR D 1 61  ? 89.443  97.506  164.864 1.00 46.28  ? 32  THR B C     1 
ATOM   6892  O O     . THR D 1 61  ? 88.591  98.195  164.293 1.00 46.28  ? 32  THR B O     1 
ATOM   6893  C CB    . THR D 1 61  ? 88.077  95.479  165.378 1.00 46.28  ? 32  THR B CB    1 
ATOM   6894  O OG1   . THR D 1 61  ? 86.954  96.151  164.795 1.00 46.28  ? 32  THR B OG1   1 
ATOM   6895  C CG2   . THR D 1 61  ? 88.042  95.727  166.901 1.00 46.28  ? 32  THR B CG2   1 
ATOM   6896  N N     . GLY D 1 62  ? 90.411  98.043  165.617 1.00 45.73  ? 33  GLY B N     1 
ATOM   6897  C CA    . GLY D 1 62  ? 90.617  99.472  165.731 1.00 45.73  ? 33  GLY B CA    1 
ATOM   6898  C C     . GLY D 1 62  ? 89.961  100.130 166.926 1.00 45.73  ? 33  GLY B C     1 
ATOM   6899  O O     . GLY D 1 62  ? 90.295  101.281 167.234 1.00 45.73  ? 33  GLY B O     1 
ATOM   6900  N N     . ILE D 1 63  ? 89.043  99.452  167.603 1.00 43.08  ? 34  ILE B N     1 
ATOM   6901  C CA    . ILE D 1 63  ? 88.460  100.014 168.828 1.00 43.08  ? 34  ILE B CA    1 
ATOM   6902  C C     . ILE D 1 63  ? 89.536  100.025 169.912 1.00 43.08  ? 34  ILE B C     1 
ATOM   6903  O O     . ILE D 1 63  ? 90.271  99.030  170.038 1.00 43.08  ? 34  ILE B O     1 
ATOM   6904  C CB    . ILE D 1 63  ? 87.222  99.203  169.266 1.00 43.08  ? 34  ILE B CB    1 
ATOM   6905  C CG1   . ILE D 1 63  ? 85.955  99.481  168.413 1.00 43.08  ? 34  ILE B CG1   1 
ATOM   6906  C CG2   . ILE D 1 63  ? 86.848  99.467  170.739 1.00 43.08  ? 34  ILE B CG2   1 
ATOM   6907  C CD1   . ILE D 1 63  ? 86.059  99.490  166.890 1.00 43.08  ? 34  ILE B CD1   1 
ATOM   6908  N N     . PRO D 1 64  ? 89.698  101.089 170.709 1.00 38.59  ? 35  PRO B N     1 
ATOM   6909  C CA    . PRO D 1 64  ? 90.791  101.086 171.689 1.00 38.59  ? 35  PRO B CA    1 
ATOM   6910  C C     . PRO D 1 64  ? 90.557  100.109 172.830 1.00 38.59  ? 35  PRO B C     1 
ATOM   6911  O O     . PRO D 1 64  ? 89.430  99.715  173.140 1.00 38.59  ? 35  PRO B O     1 
ATOM   6912  C CB    . PRO D 1 64  ? 90.816  102.527 172.212 1.00 38.59  ? 35  PRO B CB    1 
ATOM   6913  C CG    . PRO D 1 64  ? 90.055  103.306 171.247 1.00 38.59  ? 35  PRO B CG    1 
ATOM   6914  C CD    . PRO D 1 64  ? 89.004  102.392 170.746 1.00 38.59  ? 35  PRO B CD    1 
ATOM   6915  N N     . ILE D 1 65  ? 91.664  99.726  173.458 1.00 39.59  ? 36  ILE B N     1 
ATOM   6916  C CA    . ILE D 1 65  ? 91.668  98.958  174.698 1.00 39.59  ? 36  ILE B CA    1 
ATOM   6917  C C     . ILE D 1 65  ? 91.605  99.968  175.836 1.00 39.59  ? 36  ILE B C     1 
ATOM   6918  O O     . ILE D 1 65  ? 92.123  101.084 175.721 1.00 39.59  ? 36  ILE B O     1 
ATOM   6919  C CB    . ILE D 1 65  ? 92.913  98.044  174.809 1.00 39.59  ? 36  ILE B CB    1 
ATOM   6920  C CG1   . ILE D 1 65  ? 93.268  97.413  173.449 1.00 39.59  ? 36  ILE B CG1   1 
ATOM   6921  C CG2   . ILE D 1 65  ? 92.687  96.937  175.854 1.00 39.59  ? 36  ILE B CG2   1 
ATOM   6922  C CD1   . ILE D 1 65  ? 94.299  96.292  173.505 1.00 39.59  ? 36  ILE B CD1   1 
ATOM   6923  N N     . LYS D 1 66  ? 90.941  99.592  176.933 1.00 38.29  ? 37  LYS B N     1 
ATOM   6924  C CA    . LYS D 1 66  ? 90.794  100.504 178.064 1.00 38.29  ? 37  LYS B CA    1 
ATOM   6925  C C     . LYS D 1 66  ? 92.145  100.843 178.685 1.00 38.29  ? 37  LYS B C     1 
ATOM   6926  O O     . LYS D 1 66  ? 92.388  101.997 179.054 1.00 38.29  ? 37  LYS B O     1 
ATOM   6927  C CB    . LYS D 1 66  ? 89.864  99.889  179.111 1.00 38.29  ? 37  LYS B CB    1 
ATOM   6928  C CG    . LYS D 1 66  ? 89.323  100.874 180.149 1.00 38.29  ? 37  LYS B CG    1 
ATOM   6929  C CD    . LYS D 1 66  ? 88.213  101.749 179.581 1.00 38.29  ? 37  LYS B CD    1 
ATOM   6930  C CE    . LYS D 1 66  ? 87.523  102.555 180.669 1.00 38.29  ? 37  LYS B CE    1 
ATOM   6931  N NZ    . LYS D 1 66  ? 86.307  103.249 180.163 1.00 38.29  ? 37  LYS B NZ    1 
ATOM   6932  N N     . LEU D 1 67  ? 93.024  99.848  178.827 1.00 37.04  ? 38  LEU B N     1 
ATOM   6933  C CA    . LEU D 1 67  ? 94.386  100.042 179.326 1.00 37.04  ? 38  LEU B CA    1 
ATOM   6934  C C     . LEU D 1 67  ? 95.329  99.231  178.450 1.00 37.04  ? 38  LEU B C     1 
ATOM   6935  O O     . LEU D 1 67  ? 95.328  97.998  178.516 1.00 37.04  ? 38  LEU B O     1 
ATOM   6936  C CB    . LEU D 1 67  ? 94.530  99.614  180.789 1.00 37.04  ? 38  LEU B CB    1 
ATOM   6937  C CG    . LEU D 1 67  ? 94.052  100.532 181.920 1.00 37.04  ? 38  LEU B CG    1 
ATOM   6938  C CD1   . LEU D 1 67  ? 92.570  100.355 182.246 1.00 37.04  ? 38  LEU B CD1   1 
ATOM   6939  C CD2   . LEU D 1 67  ? 94.910  100.301 183.157 1.00 37.04  ? 38  LEU B CD2   1 
ATOM   6940  N N     . ALA D 1 68  ? 96.137  99.911  177.641 1.00 34.83  ? 39  ALA B N     1 
ATOM   6941  C CA    . ALA D 1 68  ? 97.123  99.227  176.818 1.00 34.83  ? 39  ALA B CA    1 
ATOM   6942  C C     . ALA D 1 68  ? 98.121  100.241 176.282 1.00 34.83  ? 39  ALA B C     1 
ATOM   6943  O O     . ALA D 1 68  ? 97.768  101.386 175.994 1.00 34.83  ? 39  ALA B O     1 
ATOM   6944  C CB    . ALA D 1 68  ? 96.467  98.472  175.658 1.00 34.83  ? 39  ALA B CB    1 
ATOM   6945  N N     . ALA D 1 69  ? 99.373  99.796  176.154 1.00 33.57  ? 40  ALA B N     1 
ATOM   6946  C CA    . ALA D 1 69  ? 100.457 100.595 175.580 1.00 33.57  ? 40  ALA B CA    1 
ATOM   6947  C C     . ALA D 1 69  ? 100.712 101.877 176.368 1.00 33.57  ? 40  ALA B C     1 
ATOM   6948  O O     . ALA D 1 69  ? 101.126 102.890 175.801 1.00 33.57  ? 40  ALA B O     1 
ATOM   6949  C CB    . ALA D 1 69  ? 100.178 100.928 174.112 1.00 33.57  ? 40  ALA B CB    1 
ATOM   6950  N N     . GLY D 1 70  ? 100.467 101.848 177.679 1.00 31.64  ? 41  GLY B N     1 
ATOM   6951  C CA    . GLY D 1 70  ? 100.648 102.999 178.534 1.00 31.64  ? 41  GLY B CA    1 
ATOM   6952  C C     . GLY D 1 70  ? 99.464  103.942 178.600 1.00 31.64  ? 41  GLY B C     1 
ATOM   6953  O O     . GLY D 1 70  ? 99.372  104.726 179.550 1.00 31.64  ? 41  GLY B O     1 
ATOM   6954  N N     . PHE D 1 71  ? 98.556  103.886 177.631 1.00 30.87  ? 42  PHE B N     1 
ATOM   6955  C CA    . PHE D 1 71  ? 97.372  104.728 177.643 1.00 30.87  ? 42  PHE B CA    1 
ATOM   6956  C C     . PHE D 1 71  ? 96.321  104.146 178.577 1.00 30.87  ? 42  PHE B C     1 
ATOM   6957  O O     . PHE D 1 71  ? 96.200  102.926 178.720 1.00 30.87  ? 42  PHE B O     1 
ATOM   6958  C CB    . PHE D 1 71  ? 96.783  104.856 176.238 1.00 30.87  ? 42  PHE B CB    1 
ATOM   6959  C CG    . PHE D 1 71  ? 97.352  105.985 175.438 1.00 30.87  ? 42  PHE B CG    1 
ATOM   6960  C CD1   . PHE D 1 71  ? 98.500  105.812 174.692 1.00 30.87  ? 42  PHE B CD1   1 
ATOM   6961  C CD2   . PHE D 1 71  ? 96.717  107.211 175.402 1.00 30.87  ? 42  PHE B CD2   1 
ATOM   6962  C CE1   . PHE D 1 71  ? 99.016  106.845 173.948 1.00 30.87  ? 42  PHE B CE1   1 
ATOM   6963  C CE2   . PHE D 1 71  ? 97.227  108.246 174.659 1.00 30.87  ? 42  PHE B CE2   1 
ATOM   6964  C CZ    . PHE D 1 71  ? 98.377  108.063 173.930 1.00 30.87  ? 42  PHE B CZ    1 
ATOM   6965  N N     . VAL D 1 72  ? 95.571  105.033 179.231 1.00 33.62  ? 43  VAL B N     1 
ATOM   6966  C CA    . VAL D 1 72  ? 94.364  104.670 179.965 1.00 33.62  ? 43  VAL B CA    1 
ATOM   6967  C C     . VAL D 1 72  ? 93.270  105.662 179.594 1.00 33.62  ? 43  VAL B C     1 
ATOM   6968  O O     . VAL D 1 72  ? 93.512  106.872 179.517 1.00 33.62  ? 43  VAL B O     1 
ATOM   6969  C CB    . VAL D 1 72  ? 94.591  104.619 181.498 1.00 33.62  ? 43  VAL B CB    1 
ATOM   6970  C CG1   . VAL D 1 72  ? 95.858  103.844 181.831 1.00 33.62  ? 43  VAL B CG1   1 
ATOM   6971  C CG2   . VAL D 1 72  ? 94.663  106.002 182.118 1.00 33.62  ? 43  VAL B CG2   1 
ATOM   6972  N N     . GLY D 1 73  ? 92.075  105.141 179.325 1.00 34.98  ? 44  GLY B N     1 
ATOM   6973  C CA    . GLY D 1 73  ? 90.956  105.989 178.969 1.00 34.98  ? 44  GLY B CA    1 
ATOM   6974  C C     . GLY D 1 73  ? 91.180  106.704 177.644 1.00 34.98  ? 44  GLY B C     1 
ATOM   6975  O O     . GLY D 1 73  ? 92.008  106.313 176.818 1.00 34.98  ? 44  GLY B O     1 
ATOM   6976  N N     . GLN D 1 74  ? 90.423  107.789 177.465 1.00 31.38  ? 45  GLN B N     1 
ATOM   6977  C CA    . GLN D 1 74  ? 90.530  108.644 176.283 1.00 31.38  ? 45  GLN B CA    1 
ATOM   6978  C C     . GLN D 1 74  ? 90.193  107.862 175.013 1.00 31.38  ? 45  GLN B C     1 
ATOM   6979  O O     . GLN D 1 74  ? 90.934  107.870 174.028 1.00 31.38  ? 45  GLN B O     1 
ATOM   6980  C CB    . GLN D 1 74  ? 91.925  109.272 176.203 1.00 31.38  ? 45  GLN B CB    1 
ATOM   6981  C CG    . GLN D 1 74  ? 91.974  110.575 175.437 1.00 31.38  ? 45  GLN B CG    1 
ATOM   6982  C CD    . GLN D 1 74  ? 91.406  111.739 176.219 1.00 31.38  ? 45  GLN B CD    1 
ATOM   6983  O OE1   . GLN D 1 74  ? 90.358  112.281 175.871 1.00 31.38  ? 45  GLN B OE1   1 
ATOM   6984  N NE2   . GLN D 1 74  ? 92.098  112.137 177.278 1.00 31.38  ? 45  GLN B NE2   1 
ATOM   6985  N N     . LEU D 1 75  ? 89.044  107.185 175.042 1.00 34.21  ? 46  LEU B N     1 
ATOM   6986  C CA    . LEU D 1 75  ? 88.714  106.229 173.990 1.00 34.21  ? 46  LEU B CA    1 
ATOM   6987  C C     . LEU D 1 75  ? 88.397  106.922 172.670 1.00 34.21  ? 46  LEU B C     1 
ATOM   6988  O O     . LEU D 1 75  ? 88.806  106.448 171.604 1.00 34.21  ? 46  LEU B O     1 
ATOM   6989  C CB    . LEU D 1 75  ? 87.538  105.358 174.431 1.00 34.21  ? 46  LEU B CB    1 
ATOM   6990  C CG    . LEU D 1 75  ? 87.707  104.573 175.736 1.00 34.21  ? 46  LEU B CG    1 
ATOM   6991  C CD1   . LEU D 1 75  ? 86.397  103.912 176.127 1.00 34.21  ? 46  LEU B CD1   1 
ATOM   6992  C CD2   . LEU D 1 75  ? 88.814  103.537 175.617 1.00 34.21  ? 46  LEU B CD2   1 
ATOM   6993  N N     . GLU D 1 76  ? 87.665  108.038 172.716 1.00 37.90  ? 47  GLU B N     1 
ATOM   6994  C CA    . GLU D 1 76  ? 87.250  108.701 171.482 1.00 37.90  ? 47  GLU B CA    1 
ATOM   6995  C C     . GLU D 1 76  ? 88.448  109.270 170.731 1.00 37.90  ? 47  GLU B C     1 
ATOM   6996  O O     . GLU D 1 76  ? 88.601  109.046 169.523 1.00 37.90  ? 47  GLU B O     1 
ATOM   6997  C CB    . GLU D 1 76  ? 86.240  109.803 171.800 1.00 37.90  ? 47  GLU B CB    1 
ATOM   6998  C CG    . GLU D 1 76  ? 85.851  110.656 170.592 1.00 37.90  ? 47  GLU B CG    1 
ATOM   6999  C CD    . GLU D 1 76  ? 84.502  111.346 170.743 1.00 37.90  ? 47  GLU B CD    1 
ATOM   7000  O OE1   . GLU D 1 76  ? 83.532  110.702 171.197 1.00 37.90  ? 47  GLU B OE1   1 
ATOM   7001  O OE2   . GLU D 1 76  ? 84.414  112.544 170.402 1.00 37.90  ? 47  GLU B OE2   1 
ATOM   7002  N N     . ALA D 1 77  ? 89.318  109.998 171.434 1.00 32.68  ? 48  ALA B N     1 
ATOM   7003  C CA    . ALA D 1 77  ? 90.500  110.551 170.786 1.00 32.68  ? 48  ALA B CA    1 
ATOM   7004  C C     . ALA D 1 77  ? 91.466  109.458 170.354 1.00 32.68  ? 48  ALA B C     1 
ATOM   7005  O O     . ALA D 1 77  ? 92.131  109.602 169.326 1.00 32.68  ? 48  ALA B O     1 
ATOM   7006  C CB    . ALA D 1 77  ? 91.204  111.534 171.716 1.00 32.68  ? 48  ALA B CB    1 
ATOM   7007  N N     . ARG D 1 78  ? 91.560  108.366 171.117 1.00 32.74  ? 49  ARG B N     1 
ATOM   7008  C CA    . ARG D 1 78  ? 92.414  107.254 170.706 1.00 32.74  ? 49  ARG B CA    1 
ATOM   7009  C C     . ARG D 1 78  ? 91.911  106.616 169.418 1.00 32.74  ? 49  ARG B C     1 
ATOM   7010  O O     . ARG D 1 78  ? 92.703  106.309 168.522 1.00 32.74  ? 49  ARG B O     1 
ATOM   7011  C CB    . ARG D 1 78  ? 92.491  106.200 171.808 1.00 32.74  ? 49  ARG B CB    1 
ATOM   7012  C CG    . ARG D 1 78  ? 93.578  106.451 172.842 1.00 32.74  ? 49  ARG B CG    1 
ATOM   7013  C CD    . ARG D 1 78  ? 93.400  105.578 174.078 1.00 32.74  ? 49  ARG B CD    1 
ATOM   7014  N NE    . ARG D 1 78  ? 93.932  104.237 173.869 1.00 32.74  ? 49  ARG B NE    1 
ATOM   7015  C CZ    . ARG D 1 78  ? 94.049  103.300 174.803 1.00 32.74  ? 49  ARG B CZ    1 
ATOM   7016  N NH1   . ARG D 1 78  ? 93.633  103.490 176.047 1.00 32.74  ? 49  ARG B NH1   1 
ATOM   7017  N NH2   . ARG D 1 78  ? 94.587  102.129 174.477 1.00 32.74  ? 49  ARG B NH2   1 
ATOM   7018  N N     . GLU D 1 79  ? 90.598  106.404 169.308 1.00 38.16  ? 50  GLU B N     1 
ATOM   7019  C CA    . GLU D 1 79  ? 90.044  105.830 168.085 1.00 38.16  ? 50  GLU B CA    1 
ATOM   7020  C C     . GLU D 1 79  ? 90.221  106.777 166.904 1.00 38.16  ? 50  GLU B C     1 
ATOM   7021  O O     . GLU D 1 79  ? 90.525  106.338 165.785 1.00 38.16  ? 50  GLU B O     1 
ATOM   7022  C CB    . GLU D 1 79  ? 88.569  105.493 168.294 1.00 38.16  ? 50  GLU B CB    1 
ATOM   7023  C CG    . GLU D 1 79  ? 87.976  104.600 167.220 1.00 38.16  ? 50  GLU B CG    1 
ATOM   7024  C CD    . GLU D 1 79  ? 86.554  104.177 167.532 1.00 38.16  ? 50  GLU B CD    1 
ATOM   7025  O OE1   . GLU D 1 79  ? 86.036  104.555 168.604 1.00 38.16  ? 50  GLU B OE1   1 
ATOM   7026  O OE2   . GLU D 1 79  ? 85.951  103.466 166.701 1.00 38.16  ? 50  GLU B OE2   1 
ATOM   7027  N N     . ALA D 1 80  ? 90.038  108.079 167.138 1.00 37.25  ? 51  ALA B N     1 
ATOM   7028  C CA    . ALA D 1 80  ? 90.260  109.061 166.082 1.00 37.25  ? 51  ALA B CA    1 
ATOM   7029  C C     . ALA D 1 80  ? 91.715  109.067 165.631 1.00 37.25  ? 51  ALA B C     1 
ATOM   7030  O O     . ALA D 1 80  ? 92.000  109.126 164.430 1.00 37.25  ? 51  ALA B O     1 
ATOM   7031  C CB    . ALA D 1 80  ? 89.846  110.446 166.570 1.00 37.25  ? 51  ALA B CB    1 
ATOM   7032  N N     . ALA D 1 81  ? 92.651  108.992 166.578 1.00 33.08  ? 52  ALA B N     1 
ATOM   7033  C CA    . ALA D 1 81  ? 94.062  108.940 166.221 1.00 33.08  ? 52  ALA B CA    1 
ATOM   7034  C C     . ALA D 1 81  ? 94.406  107.647 165.500 1.00 33.08  ? 52  ALA B C     1 
ATOM   7035  O O     . ALA D 1 81  ? 95.276  107.645 164.627 1.00 33.08  ? 52  ALA B O     1 
ATOM   7036  C CB    . ALA D 1 81  ? 94.926  109.098 167.469 1.00 33.08  ? 52  ALA B CB    1 
ATOM   7037  N N     . GLY D 1 82  ? 93.743  106.543 165.844 1.00 33.67  ? 53  GLY B N     1 
ATOM   7038  C CA    . GLY D 1 82  ? 93.953  105.309 165.104 1.00 33.67  ? 53  GLY B CA    1 
ATOM   7039  C C     . GLY D 1 82  ? 93.491  105.416 163.666 1.00 33.67  ? 53  GLY B C     1 
ATOM   7040  O O     . GLY D 1 82  ? 94.166  104.945 162.743 1.00 33.67  ? 53  GLY B O     1 
ATOM   7041  N N     . LEU D 1 83  ? 92.331  106.039 163.455 1.00 40.27  ? 54  LEU B N     1 
ATOM   7042  C CA    . LEU D 1 83  ? 91.858  106.258 162.093 1.00 40.27  ? 54  LEU B CA    1 
ATOM   7043  C C     . LEU D 1 83  ? 92.785  107.204 161.336 1.00 40.27  ? 54  LEU B C     1 
ATOM   7044  O O     . LEU D 1 83  ? 93.005  107.033 160.134 1.00 40.27  ? 54  LEU B O     1 
ATOM   7045  C CB    . LEU D 1 83  ? 90.427  106.797 162.118 1.00 40.27  ? 54  LEU B CB    1 
ATOM   7046  C CG    . LEU D 1 83  ? 89.639  106.805 160.804 1.00 40.27  ? 54  LEU B CG    1 
ATOM   7047  C CD1   . LEU D 1 83  ? 89.392  105.395 160.288 1.00 40.27  ? 54  LEU B CD1   1 
ATOM   7048  C CD2   . LEU D 1 83  ? 88.318  107.534 160.988 1.00 40.27  ? 54  LEU B CD2   1 
ATOM   7049  N N     . VAL D 1 84  ? 93.355  108.195 162.026 1.00 37.74  ? 55  VAL B N     1 
ATOM   7050  C CA    . VAL D 1 84  ? 94.319  109.085 161.381 1.00 37.74  ? 55  VAL B CA    1 
ATOM   7051  C C     . VAL D 1 84  ? 95.600  108.330 161.036 1.00 37.74  ? 55  VAL B C     1 
ATOM   7052  O O     . VAL D 1 84  ? 96.233  108.600 160.011 1.00 37.74  ? 55  VAL B O     1 
ATOM   7053  C CB    . VAL D 1 84  ? 94.594  110.313 162.271 1.00 37.74  ? 55  VAL B CB    1 
ATOM   7054  C CG1   . VAL D 1 84  ? 95.821  111.099 161.787 1.00 37.74  ? 55  VAL B CG1   1 
ATOM   7055  C CG2   . VAL D 1 84  ? 93.379  111.226 162.288 1.00 37.74  ? 55  VAL B CG2   1 
ATOM   7056  N N     . VAL D 1 85  ? 96.013  107.391 161.888 1.00 36.27  ? 56  VAL B N     1 
ATOM   7057  C CA    . VAL D 1 85  ? 97.195  106.583 161.595 1.00 36.27  ? 56  VAL B CA    1 
ATOM   7058  C C     . VAL D 1 85  ? 96.950  105.727 160.358 1.00 36.27  ? 56  VAL B C     1 
ATOM   7059  O O     . VAL D 1 85  ? 97.820  105.607 159.487 1.00 36.27  ? 56  VAL B O     1 
ATOM   7060  C CB    . VAL D 1 85  ? 97.574  105.734 162.827 1.00 36.27  ? 56  VAL B CB    1 
ATOM   7061  C CG1   . VAL D 1 85  ? 98.473  104.538 162.468 1.00 36.27  ? 56  VAL B CG1   1 
ATOM   7062  C CG2   . VAL D 1 85  ? 98.271  106.600 163.857 1.00 36.27  ? 56  VAL B CG2   1 
ATOM   7063  N N     . ASP D 1 86  ? 95.766  105.121 160.260 1.00 41.35  ? 57  ASP B N     1 
ATOM   7064  C CA    . ASP D 1 86  ? 95.439  104.355 159.060 1.00 41.35  ? 57  ASP B CA    1 
ATOM   7065  C C     . ASP D 1 86  ? 95.337  105.253 157.832 1.00 41.35  ? 57  ASP B C     1 
ATOM   7066  O O     . ASP D 1 86  ? 95.691  104.828 156.727 1.00 41.35  ? 57  ASP B O     1 
ATOM   7067  C CB    . ASP D 1 86  ? 94.138  103.580 159.266 1.00 41.35  ? 57  ASP B CB    1 
ATOM   7068  C CG    . ASP D 1 86  ? 94.304  102.392 160.200 1.00 41.35  ? 57  ASP B CG    1 
ATOM   7069  O OD1   . ASP D 1 86  ? 95.352  101.714 160.145 1.00 41.35  ? 57  ASP B OD1   1 
ATOM   7070  O OD2   . ASP D 1 86  ? 93.384  102.139 161.003 1.00 41.35  ? 57  ASP B OD2   1 
ATOM   7071  N N     . MET D 1 87  ? 94.861  106.487 158.002 1.00 43.24  ? 58  MET B N     1 
ATOM   7072  C CA    . MET D 1 87  ? 94.879  107.444 156.897 1.00 43.24  ? 58  MET B CA    1 
ATOM   7073  C C     . MET D 1 87  ? 96.307  107.799 156.496 1.00 43.24  ? 58  MET B C     1 
ATOM   7074  O O     . MET D 1 87  ? 96.560  108.111 155.328 1.00 43.24  ? 58  MET B O     1 
ATOM   7075  C CB    . MET D 1 87  ? 94.112  108.719 157.272 1.00 43.24  ? 58  MET B CB    1 
ATOM   7076  C CG    . MET D 1 87  ? 92.735  108.811 156.634 1.00 43.24  ? 58  MET B CG    1 
ATOM   7077  S SD    . MET D 1 87  ? 91.621  110.089 157.266 1.00 43.24  ? 58  MET B SD    1 
ATOM   7078  C CE    . MET D 1 87  ? 92.719  111.466 157.553 1.00 43.24  ? 58  MET B CE    1 
ATOM   7079  N N     . ILE D 1 88  ? 97.240  107.774 157.449 1.00 38.94  ? 59  ILE B N     1 
ATOM   7080  C CA    . ILE D 1 88  ? 98.632  108.121 157.175 1.00 38.94  ? 59  ILE B CA    1 
ATOM   7081  C C     . ILE D 1 88  ? 99.375  106.959 156.519 1.00 38.94  ? 59  ILE B C     1 
ATOM   7082  O O     . ILE D 1 88  ? 100.328 107.184 155.763 1.00 38.94  ? 59  ILE B O     1 
ATOM   7083  C CB    . ILE D 1 88  ? 99.312  108.572 158.483 1.00 38.94  ? 59  ILE B CB    1 
ATOM   7084  C CG1   . ILE D 1 88  ? 98.817  109.971 158.872 1.00 38.94  ? 59  ILE B CG1   1 
ATOM   7085  C CG2   . ILE D 1 88  ? 100.851 108.594 158.350 1.00 38.94  ? 59  ILE B CG2   1 
ATOM   7086  C CD1   . ILE D 1 88  ? 99.028  110.343 160.330 1.00 38.94  ? 59  ILE B CD1   1 
ATOM   7087  N N     . LYS D 1 89  ? 98.988  105.713 156.816 1.00 39.76  ? 60  LYS B N     1 
ATOM   7088  C CA    . LYS D 1 89  ? 99.649  104.566 156.194 1.00 39.76  ? 60  LYS B CA    1 
ATOM   7089  C C     . LYS D 1 89  ? 99.446  104.567 154.683 1.00 39.76  ? 60  LYS B C     1 
ATOM   7090  O O     . LYS D 1 89  ? 100.383 104.289 153.925 1.00 39.76  ? 60  LYS B O     1 
ATOM   7091  C CB    . LYS D 1 89  ? 99.136  103.264 156.807 1.00 39.76  ? 60  LYS B CB    1 
ATOM   7092  C CG    . LYS D 1 89  ? 99.569  103.035 158.251 1.00 39.76  ? 60  LYS B CG    1 
ATOM   7093  C CD    . LYS D 1 89  ? 101.013 102.568 158.346 1.00 39.76  ? 60  LYS B CD    1 
ATOM   7094  C CE    . LYS D 1 89  ? 101.398 102.238 159.778 1.00 39.76  ? 60  LYS B CE    1 
ATOM   7095  N NZ    . LYS D 1 89  ? 100.719 101.012 160.280 1.00 39.76  ? 60  LYS B NZ    1 
ATOM   7096  N N     . GLN D 1 90  ? 98.233  104.871 154.231 1.00 47.01  ? 61  GLN B N     1 
ATOM   7097  C CA    . GLN D 1 90  ? 98.004  105.278 152.855 1.00 47.01  ? 61  GLN B CA    1 
ATOM   7098  C C     . GLN D 1 90  ? 98.387  106.748 152.693 1.00 47.01  ? 61  GLN B C     1 
ATOM   7099  O O     . GLN D 1 90  ? 98.627  107.463 153.665 1.00 47.01  ? 61  GLN B O     1 
ATOM   7100  C CB    . GLN D 1 90  ? 96.544  105.043 152.465 1.00 47.01  ? 61  GLN B CB    1 
ATOM   7101  C CG    . GLN D 1 90  ? 96.168  103.572 152.330 1.00 47.01  ? 61  GLN B CG    1 
ATOM   7102  C CD    . GLN D 1 90  ? 95.744  102.949 153.646 1.00 47.01  ? 61  GLN B CD    1 
ATOM   7103  O OE1   . GLN D 1 90  ? 96.474  103.011 154.634 1.00 47.01  ? 61  GLN B OE1   1 
ATOM   7104  N NE2   . GLN D 1 90  ? 94.572  102.322 153.659 1.00 47.01  ? 61  GLN B NE2   1 
ATOM   7105  N N     . LYS D 1 91  ? 98.419  107.211 151.445 1.00 48.49  ? 62  LYS B N     1 
ATOM   7106  C CA    . LYS D 1 91  ? 98.861  108.564 151.122 1.00 48.49  ? 62  LYS B CA    1 
ATOM   7107  C C     . LYS D 1 91  ? 97.706  109.579 151.144 1.00 48.49  ? 62  LYS B C     1 
ATOM   7108  O O     . LYS D 1 91  ? 97.803  110.646 150.526 1.00 48.49  ? 62  LYS B O     1 
ATOM   7109  C CB    . LYS D 1 91  ? 99.600  108.548 149.771 1.00 48.49  ? 62  LYS B CB    1 
ATOM   7110  C CG    . LYS D 1 91  ? 101.119 108.333 149.888 1.00 48.49  ? 62  LYS B CG    1 
ATOM   7111  C CD    . LYS D 1 91  ? 101.506 107.102 150.713 1.00 48.49  ? 62  LYS B CD    1 
ATOM   7112  C CE    . LYS D 1 91  ? 103.002 106.850 150.661 1.00 48.49  ? 62  LYS B CE    1 
ATOM   7113  N NZ    . LYS D 1 91  ? 103.406 105.736 151.560 1.00 48.49  ? 62  LYS B NZ    1 
ATOM   7114  N N     . LYS D 1 92  ? 96.641  109.296 151.897 1.00 48.40  ? 63  LYS B N     1 
ATOM   7115  C CA    . LYS D 1 92  ? 95.470  110.162 151.927 1.00 48.40  ? 63  LYS B CA    1 
ATOM   7116  C C     . LYS D 1 92  ? 95.638  111.374 152.843 1.00 48.40  ? 63  LYS B C     1 
ATOM   7117  O O     . LYS D 1 92  ? 94.812  112.291 152.774 1.00 48.40  ? 63  LYS B O     1 
ATOM   7118  C CB    . LYS D 1 92  ? 94.234  109.367 152.368 1.00 48.40  ? 63  LYS B CB    1 
ATOM   7119  C CG    . LYS D 1 92  ? 94.095  107.933 151.815 1.00 48.40  ? 63  LYS B CG    1 
ATOM   7120  C CD    . LYS D 1 92  ? 94.202  107.816 150.291 1.00 48.40  ? 63  LYS B CD    1 
ATOM   7121  C CE    . LYS D 1 92  ? 93.071  108.533 149.569 1.00 48.40  ? 63  LYS B CE    1 
ATOM   7122  N NZ    . LYS D 1 92  ? 93.150  108.339 148.094 1.00 48.40  ? 63  LYS B NZ    1 
ATOM   7123  N N     . MET D 1 93  ? 96.669  111.407 153.691 1.00 44.46  ? 64  MET B N     1 
ATOM   7124  C CA    . MET D 1 93  ? 96.923  112.540 154.575 1.00 44.46  ? 64  MET B CA    1 
ATOM   7125  C C     . MET D 1 93  ? 97.645  113.696 153.890 1.00 44.46  ? 64  MET B C     1 
ATOM   7126  O O     . MET D 1 93  ? 97.942  114.690 154.562 1.00 44.46  ? 64  MET B O     1 
ATOM   7127  C CB    . MET D 1 93  ? 97.758  112.085 155.781 1.00 44.46  ? 64  MET B CB    1 
ATOM   7128  C CG    . MET D 1 93  ? 97.521  112.858 157.082 1.00 44.46  ? 64  MET B CG    1 
ATOM   7129  S SD    . MET D 1 93  ? 95.899  112.618 157.820 1.00 44.46  ? 64  MET B SD    1 
ATOM   7130  C CE    . MET D 1 93  ? 95.590  114.239 158.509 1.00 44.46  ? 64  MET B CE    1 
ATOM   7131  N N     . ALA D 1 94  ? 97.947  113.599 152.595 1.00 46.38  ? 65  ALA B N     1 
ATOM   7132  C CA    . ALA D 1 94  ? 98.771  114.604 151.937 1.00 46.38  ? 65  ALA B CA    1 
ATOM   7133  C C     . ALA D 1 94  ? 98.043  115.940 151.861 1.00 46.38  ? 65  ALA B C     1 
ATOM   7134  O O     . ALA D 1 94  ? 96.866  116.000 151.494 1.00 46.38  ? 65  ALA B O     1 
ATOM   7135  C CB    . ALA D 1 94  ? 99.155  114.133 150.536 1.00 46.38  ? 65  ALA B CB    1 
ATOM   7136  N N     . GLY D 1 95  ? 98.751  117.010 152.214 1.00 46.22  ? 66  GLY B N     1 
ATOM   7137  C CA    . GLY D 1 95  ? 98.189  118.343 152.214 1.00 46.22  ? 66  GLY B CA    1 
ATOM   7138  C C     . GLY D 1 95  ? 97.354  118.705 153.425 1.00 46.22  ? 66  GLY B C     1 
ATOM   7139  O O     . GLY D 1 95  ? 96.841  119.831 153.475 1.00 46.22  ? 66  GLY B O     1 
ATOM   7140  N N     . LYS D 1 96  ? 97.206  117.803 154.397 1.00 44.43  ? 67  LYS B N     1 
ATOM   7141  C CA    . LYS D 1 96  ? 96.393  117.998 155.590 1.00 44.43  ? 67  LYS B CA    1 
ATOM   7142  C C     . LYS D 1 96  ? 97.273  117.955 156.832 1.00 44.43  ? 67  LYS B C     1 
ATOM   7143  O O     . LYS D 1 96  ? 98.458  117.615 156.779 1.00 44.43  ? 67  LYS B O     1 
ATOM   7144  C CB    . LYS D 1 96  ? 95.296  116.930 155.691 1.00 44.43  ? 67  LYS B CB    1 
ATOM   7145  C CG    . LYS D 1 96  ? 94.320  116.914 154.532 1.00 44.43  ? 67  LYS B CG    1 
ATOM   7146  C CD    . LYS D 1 96  ? 93.288  115.812 154.703 1.00 44.43  ? 67  LYS B CD    1 
ATOM   7147  C CE    . LYS D 1 96  ? 92.560  115.523 153.404 1.00 44.43  ? 67  LYS B CE    1 
ATOM   7148  N NZ    . LYS D 1 96  ? 91.502  114.494 153.583 1.00 44.43  ? 67  LYS B NZ    1 
ATOM   7149  N N     . ALA D 1 97  ? 96.666  118.315 157.959 1.00 41.15  ? 68  ALA B N     1 
ATOM   7150  C CA    . ALA D 1 97  ? 97.313  118.259 159.259 1.00 41.15  ? 68  ALA B CA    1 
ATOM   7151  C C     . ALA D 1 97  ? 96.252  117.919 160.294 1.00 41.15  ? 68  ALA B C     1 
ATOM   7152  O O     . ALA D 1 97  ? 95.055  117.915 160.002 1.00 41.15  ? 68  ALA B O     1 
ATOM   7153  C CB    . ALA D 1 97  ? 98.024  119.578 159.582 1.00 41.15  ? 68  ALA B CB    1 
ATOM   7154  N N     . LEU D 1 98  ? 96.710  117.612 161.504 1.00 38.72  ? 69  LEU B N     1 
ATOM   7155  C CA    . LEU D 1 98  ? 95.865  117.238 162.629 1.00 38.72  ? 69  LEU B CA    1 
ATOM   7156  C C     . LEU D 1 98  ? 95.890  118.361 163.656 1.00 38.72  ? 69  LEU B C     1 
ATOM   7157  O O     . LEU D 1 98  ? 96.879  119.088 163.764 1.00 38.72  ? 69  LEU B O     1 
ATOM   7158  C CB    . LEU D 1 98  ? 96.364  115.936 163.254 1.00 38.72  ? 69  LEU B CB    1 
ATOM   7159  C CG    . LEU D 1 98  ? 95.530  115.235 164.330 1.00 38.72  ? 69  LEU B CG    1 
ATOM   7160  C CD1   . LEU D 1 98  ? 94.269  114.610 163.745 1.00 38.72  ? 69  LEU B CD1   1 
ATOM   7161  C CD2   . LEU D 1 98  ? 96.362  114.174 165.044 1.00 38.72  ? 69  LEU B CD2   1 
ATOM   7162  N N     . LEU D 1 99  ? 94.789  118.511 164.395 1.00 38.04  ? 70  LEU B N     1 
ATOM   7163  C CA    . LEU D 1 99  ? 94.669  119.523 165.448 1.00 38.04  ? 70  LEU B CA    1 
ATOM   7164  C C     . LEU D 1 99  ? 94.022  118.868 166.657 1.00 38.04  ? 70  LEU B C     1 
ATOM   7165  O O     . LEU D 1 99  ? 92.836  118.538 166.620 1.00 38.04  ? 70  LEU B O     1 
ATOM   7166  C CB    . LEU D 1 99  ? 93.849  120.727 164.977 1.00 38.04  ? 70  LEU B CB    1 
ATOM   7167  C CG    . LEU D 1 99  ? 93.511  121.847 165.974 1.00 38.04  ? 70  LEU B CG    1 
ATOM   7168  C CD1   . LEU D 1 99  ? 94.755  122.597 166.397 1.00 38.04  ? 70  LEU B CD1   1 
ATOM   7169  C CD2   . LEU D 1 99  ? 92.512  122.800 165.359 1.00 38.04  ? 70  LEU B CD2   1 
ATOM   7170  N N     . LEU D 1 100 ? 94.791  118.707 167.730 1.00 50.54  ? 71  LEU B N     1 
ATOM   7171  C CA    . LEU D 1 100 ? 94.277  118.180 168.993 1.00 50.54  ? 71  LEU B CA    1 
ATOM   7172  C C     . LEU D 1 100 ? 93.796  119.363 169.825 1.00 50.54  ? 71  LEU B C     1 
ATOM   7173  O O     . LEU D 1 100 ? 94.599  120.109 170.390 1.00 50.54  ? 71  LEU B O     1 
ATOM   7174  C CB    . LEU D 1 100 ? 95.351  117.376 169.715 1.00 50.54  ? 71  LEU B CB    1 
ATOM   7175  C CG    . LEU D 1 100 ? 95.968  116.209 168.938 1.00 50.54  ? 71  LEU B CG    1 
ATOM   7176  C CD1   . LEU D 1 100 ? 97.111  115.601 169.723 1.00 50.54  ? 71  LEU B CD1   1 
ATOM   7177  C CD2   . LEU D 1 100 ? 94.930  115.153 168.616 1.00 50.54  ? 71  LEU B CD2   1 
ATOM   7178  N N     . ALA D 1 101 ? 92.478  119.534 169.894 1.00 39.91  ? 72  ALA B N     1 
ATOM   7179  C CA    . ALA D 1 101 ? 91.846  120.611 170.647 1.00 39.91  ? 72  ALA B CA    1 
ATOM   7180  C C     . ALA D 1 101 ? 91.304  120.044 171.949 1.00 39.91  ? 72  ALA B C     1 
ATOM   7181  O O     . ALA D 1 101 ? 90.481  119.124 171.932 1.00 39.91  ? 72  ALA B O     1 
ATOM   7182  C CB    . ALA D 1 101 ? 90.723  121.255 169.838 1.00 39.91  ? 72  ALA B CB    1 
ATOM   7183  N N     . GLY D 1 102 ? 91.764  120.586 173.072 1.00 35.34  ? 73  GLY B N     1 
ATOM   7184  C CA    . GLY D 1 102 ? 91.241  120.177 174.353 1.00 35.34  ? 73  GLY B CA    1 
ATOM   7185  C C     . GLY D 1 102 ? 91.927  120.864 175.516 1.00 35.34  ? 73  GLY B C     1 
ATOM   7186  O O     . GLY D 1 102 ? 92.908  121.585 175.325 1.00 35.34  ? 73  GLY B O     1 
ATOM   7187  N N     . PRO D 1 103 ? 91.438  120.660 176.741 1.00 35.39  ? 74  PRO B N     1 
ATOM   7188  C CA    . PRO D 1 103 ? 92.051  121.329 177.898 1.00 35.39  ? 74  PRO B CA    1 
ATOM   7189  C C     . PRO D 1 103 ? 93.458  120.815 178.152 1.00 35.39  ? 74  PRO B C     1 
ATOM   7190  O O     . PRO D 1 103 ? 93.830  119.753 177.632 1.00 35.39  ? 74  PRO B O     1 
ATOM   7191  C CB    . PRO D 1 103 ? 91.114  120.964 179.059 1.00 35.39  ? 74  PRO B CB    1 
ATOM   7192  C CG    . PRO D 1 103 ? 89.849  120.587 178.425 1.00 35.39  ? 74  PRO B CG    1 
ATOM   7193  C CD    . PRO D 1 103 ? 90.220  119.931 177.143 1.00 35.39  ? 74  PRO B CD    1 
ATOM   7194  N N     . PRO D 1 104 ? 94.277  121.532 178.928 1.00 31.07  ? 75  PRO B N     1 
ATOM   7195  C CA    . PRO D 1 104 ? 95.609  121.010 179.245 1.00 31.07  ? 75  PRO B CA    1 
ATOM   7196  C C     . PRO D 1 104 ? 95.531  119.766 180.111 1.00 31.07  ? 75  PRO B C     1 
ATOM   7197  O O     . PRO D 1 104 ? 94.584  119.567 180.874 1.00 31.07  ? 75  PRO B O     1 
ATOM   7198  C CB    . PRO D 1 104 ? 96.282  122.163 180.000 1.00 31.07  ? 75  PRO B CB    1 
ATOM   7199  C CG    . PRO D 1 104 ? 95.452  123.349 179.735 1.00 31.07  ? 75  PRO B CG    1 
ATOM   7200  C CD    . PRO D 1 104 ? 94.069  122.844 179.565 1.00 31.07  ? 75  PRO B CD    1 
ATOM   7201  N N     . GLY D 1 105 ? 96.548  118.922 179.982 1.00 31.03  ? 76  GLY B N     1 
ATOM   7202  C CA    . GLY D 1 105 ? 96.623  117.718 180.778 1.00 31.03  ? 76  GLY B CA    1 
ATOM   7203  C C     . GLY D 1 105 ? 95.693  116.602 180.361 1.00 31.03  ? 76  GLY B C     1 
ATOM   7204  O O     . GLY D 1 105 ? 95.548  115.638 181.120 1.00 31.03  ? 76  GLY B O     1 
ATOM   7205  N N     . THR D 1 106 ? 95.061  116.695 179.188 1.00 30.89  ? 77  THR B N     1 
ATOM   7206  C CA    . THR D 1 106 ? 94.176  115.659 178.669 1.00 30.89  ? 77  THR B CA    1 
ATOM   7207  C C     . THR D 1 106 ? 94.866  114.702 177.698 1.00 30.89  ? 77  THR B C     1 
ATOM   7208  O O     . THR D 1 106 ? 94.184  113.875 177.084 1.00 30.89  ? 77  THR B O     1 
ATOM   7209  C CB    . THR D 1 106 ? 92.966  116.297 177.987 1.00 30.89  ? 77  THR B CB    1 
ATOM   7210  O OG1   . THR D 1 106 ? 93.403  117.118 176.898 1.00 30.89  ? 77  THR B OG1   1 
ATOM   7211  C CG2   . THR D 1 106 ? 92.179  117.142 178.977 1.00 30.89  ? 77  THR B CG2   1 
ATOM   7212  N N     . GLY D 1 107 ? 96.187  114.796 177.532 1.00 31.19  ? 78  GLY B N     1 
ATOM   7213  C CA    . GLY D 1 107 ? 96.925  113.824 176.751 1.00 31.19  ? 78  GLY B CA    1 
ATOM   7214  C C     . GLY D 1 107 ? 97.088  114.150 175.286 1.00 31.19  ? 78  GLY B C     1 
ATOM   7215  O O     . GLY D 1 107 ? 97.112  113.232 174.461 1.00 31.19  ? 78  GLY B O     1 
ATOM   7216  N N     . LYS D 1 108 ? 97.205  115.429 174.931 1.00 34.36  ? 79  LYS B N     1 
ATOM   7217  C CA    . LYS D 1 108 ? 97.401  115.789 173.530 1.00 34.36  ? 79  LYS B CA    1 
ATOM   7218  C C     . LYS D 1 108 ? 98.795  115.391 173.057 1.00 34.36  ? 79  LYS B C     1 
ATOM   7219  O O     . LYS D 1 108 ? 98.951  114.739 172.015 1.00 34.36  ? 79  LYS B O     1 
ATOM   7220  C CB    . LYS D 1 108 ? 97.174  117.289 173.340 1.00 34.36  ? 79  LYS B CB    1 
ATOM   7221  C CG    . LYS D 1 108 ? 95.877  117.819 173.949 1.00 34.36  ? 79  LYS B CG    1 
ATOM   7222  C CD    . LYS D 1 108 ? 95.571  119.250 173.524 1.00 34.36  ? 79  LYS B CD    1 
ATOM   7223  C CE    . LYS D 1 108 ? 96.540  120.276 174.101 1.00 34.36  ? 79  LYS B CE    1 
ATOM   7224  N NZ    . LYS D 1 108 ? 96.475  120.361 175.583 1.00 34.36  ? 79  LYS B NZ    1 
ATOM   7225  N N     . THR D 1 109 ? 99.823  115.766 173.824 1.00 33.19  ? 80  THR B N     1 
ATOM   7226  C CA    . THR D 1 109 ? 101.180 115.331 173.514 1.00 33.19  ? 80  THR B CA    1 
ATOM   7227  C C     . THR D 1 109 ? 101.307 113.821 173.629 1.00 33.19  ? 80  THR B C     1 
ATOM   7228  O O     . THR D 1 109 ? 102.075 113.202 172.882 1.00 33.19  ? 80  THR B O     1 
ATOM   7229  C CB    . THR D 1 109 ? 102.181 116.011 174.450 1.00 33.19  ? 80  THR B CB    1 
ATOM   7230  O OG1   . THR D 1 109 ? 101.828 117.388 174.619 1.00 33.19  ? 80  THR B OG1   1 
ATOM   7231  C CG2   . THR D 1 109 ? 103.593 115.926 173.888 1.00 33.19  ? 80  THR B CG2   1 
ATOM   7232  N N     . ALA D 1 110 ? 100.562 113.217 174.559 1.00 31.29  ? 81  ALA B N     1 
ATOM   7233  C CA    . ALA D 1 110 ? 100.540 111.765 174.671 1.00 31.29  ? 81  ALA B CA    1 
ATOM   7234  C C     . ALA D 1 110 ? 100.012 111.124 173.397 1.00 31.29  ? 81  ALA B C     1 
ATOM   7235  O O     . ALA D 1 110 ? 100.594 110.157 172.897 1.00 31.29  ? 81  ALA B O     1 
ATOM   7236  C CB    . ALA D 1 110 ? 99.687  111.352 175.867 1.00 31.29  ? 81  ALA B CB    1 
ATOM   7237  N N     . LEU D 1 111 ? 98.923  111.664 172.844 1.00 33.22  ? 82  LEU B N     1 
ATOM   7238  C CA    . LEU D 1 111 ? 98.373  111.117 171.608 1.00 33.22  ? 82  LEU B CA    1 
ATOM   7239  C C     . LEU D 1 111 ? 99.316  111.338 170.434 1.00 33.22  ? 82  LEU B C     1 
ATOM   7240  O O     . LEU D 1 111 ? 99.429  110.476 169.557 1.00 33.22  ? 82  LEU B O     1 
ATOM   7241  C CB    . LEU D 1 111 ? 97.009  111.740 171.316 1.00 33.22  ? 82  LEU B CB    1 
ATOM   7242  C CG    . LEU D 1 111 ? 95.840  111.275 172.185 1.00 33.22  ? 82  LEU B CG    1 
ATOM   7243  C CD1   . LEU D 1 111 ? 94.652  112.206 172.015 1.00 33.22  ? 82  LEU B CD1   1 
ATOM   7244  C CD2   . LEU D 1 111 ? 95.437  109.845 171.853 1.00 33.22  ? 82  LEU B CD2   1 
ATOM   7245  N N     . ALA D 1 112 ? 99.997  112.486 170.392 1.00 35.68  ? 83  ALA B N     1 
ATOM   7246  C CA    . ALA D 1 112 ? 100.942 112.733 169.306 1.00 35.68  ? 83  ALA B CA    1 
ATOM   7247  C C     . ALA D 1 112 ? 102.113 111.757 169.357 1.00 35.68  ? 83  ALA B C     1 
ATOM   7248  O O     . ALA D 1 112 ? 102.507 111.186 168.330 1.00 35.68  ? 83  ALA B O     1 
ATOM   7249  C CB    . ALA D 1 112 ? 101.441 114.171 169.364 1.00 35.68  ? 83  ALA B CB    1 
ATOM   7250  N N     . LEU D 1 113 ? 102.679 111.542 170.548 1.00 31.34  ? 84  LEU B N     1 
ATOM   7251  C CA    . LEU D 1 113 ? 103.762 110.573 170.673 1.00 31.34  ? 84  LEU B CA    1 
ATOM   7252  C C     . LEU D 1 113 ? 103.268 109.161 170.400 1.00 31.34  ? 84  LEU B C     1 
ATOM   7253  O O     . LEU D 1 113 ? 104.009 108.348 169.840 1.00 31.34  ? 84  LEU B O     1 
ATOM   7254  C CB    . LEU D 1 113 ? 104.398 110.660 172.063 1.00 31.34  ? 84  LEU B CB    1 
ATOM   7255  C CG    . LEU D 1 113 ? 105.627 109.789 172.369 1.00 31.34  ? 84  LEU B CG    1 
ATOM   7256  C CD1   . LEU D 1 113 ? 106.859 110.256 171.620 1.00 31.34  ? 84  LEU B CD1   1 
ATOM   7257  C CD2   . LEU D 1 113 ? 105.908 109.795 173.850 1.00 31.34  ? 84  LEU B CD2   1 
ATOM   7258  N N     . GLY D 1 114 ? 102.027 108.854 170.780 1.00 31.41  ? 85  GLY B N     1 
ATOM   7259  C CA    . GLY D 1 114 ? 101.467 107.555 170.457 1.00 31.41  ? 85  GLY B CA    1 
ATOM   7260  C C     . GLY D 1 114 ? 101.333 107.339 168.964 1.00 31.41  ? 85  GLY B C     1 
ATOM   7261  O O     . GLY D 1 114 ? 101.603 106.248 168.463 1.00 31.41  ? 85  GLY B O     1 
ATOM   7262  N N     . ILE D 1 115 ? 100.913 108.376 168.234 1.00 33.40  ? 86  ILE B N     1 
ATOM   7263  C CA    . ILE D 1 115 ? 100.826 108.285 166.777 1.00 33.40  ? 86  ILE B CA    1 
ATOM   7264  C C     . ILE D 1 115 ? 102.213 108.055 166.186 1.00 33.40  ? 86  ILE B C     1 
ATOM   7265  O O     . ILE D 1 115 ? 102.410 107.166 165.346 1.00 33.40  ? 86  ILE B O     1 
ATOM   7266  C CB    . ILE D 1 115 ? 100.161 109.552 166.198 1.00 33.40  ? 86  ILE B CB    1 
ATOM   7267  C CG1   . ILE D 1 115 ? 98.662  109.569 166.534 1.00 33.40  ? 86  ILE B CG1   1 
ATOM   7268  C CG2   . ILE D 1 115 ? 100.371 109.654 164.667 1.00 33.40  ? 86  ILE B CG2   1 
ATOM   7269  C CD1   . ILE D 1 115 ? 97.989  110.927 166.380 1.00 33.40  ? 86  ILE B CD1   1 
ATOM   7270  N N     . SER D 1 116 ? 103.196 108.843 166.636 1.00 32.01  ? 87  SER B N     1 
ATOM   7271  C CA    . SER D 1 116 ? 104.547 108.726 166.092 1.00 32.01  ? 87  SER B CA    1 
ATOM   7272  C C     . SER D 1 116 ? 105.167 107.371 166.409 1.00 32.01  ? 87  SER B C     1 
ATOM   7273  O O     . SER D 1 116 ? 105.972 106.860 165.624 1.00 32.01  ? 87  SER B O     1 
ATOM   7274  C CB    . SER D 1 116 ? 105.430 109.849 166.633 1.00 32.01  ? 87  SER B CB    1 
ATOM   7275  O OG    . SER D 1 116 ? 105.972 109.503 167.893 1.00 32.01  ? 87  SER B OG    1 
ATOM   7276  N N     . GLN D 1 117 ? 104.805 106.777 167.546 1.00 32.02  ? 88  GLN B N     1 
ATOM   7277  C CA    . GLN D 1 117 ? 105.226 105.410 167.837 1.00 32.02  ? 88  GLN B CA    1 
ATOM   7278  C C     . GLN D 1 117 ? 104.474 104.407 166.970 1.00 32.02  ? 88  GLN B C     1 
ATOM   7279  O O     . GLN D 1 117 ? 105.035 103.383 166.566 1.00 32.02  ? 88  GLN B O     1 
ATOM   7280  C CB    . GLN D 1 117 ? 105.008 105.096 169.319 1.00 32.02  ? 88  GLN B CB    1 
ATOM   7281  C CG    . GLN D 1 117 ? 105.819 105.948 170.296 1.00 32.02  ? 88  GLN B CG    1 
ATOM   7282  C CD    . GLN D 1 117 ? 107.078 105.256 170.775 1.00 32.02  ? 88  GLN B CD    1 
ATOM   7283  O OE1   . GLN D 1 117 ? 107.735 104.544 170.017 1.00 32.02  ? 88  GLN B OE1   1 
ATOM   7284  N NE2   . GLN D 1 117 ? 107.423 105.466 172.039 1.00 32.02  ? 88  GLN B NE2   1 
ATOM   7285  N N     . GLU D 1 118 ? 103.199 104.680 166.680 1.00 33.70  ? 89  GLU B N     1 
ATOM   7286  C CA    . GLU D 1 118 ? 102.378 103.726 165.945 1.00 33.70  ? 89  GLU B CA    1 
ATOM   7287  C C     . GLU D 1 118 ? 102.778 103.632 164.480 1.00 33.70  ? 89  GLU B C     1 
ATOM   7288  O O     . GLU D 1 118 ? 102.580 102.580 163.861 1.00 33.70  ? 89  GLU B O     1 
ATOM   7289  C CB    . GLU D 1 118 ? 100.902 104.115 166.059 1.00 33.70  ? 89  GLU B CB    1 
ATOM   7290  C CG    . GLU D 1 118 ? 99.906  103.017 165.689 1.00 33.70  ? 89  GLU B CG    1 
ATOM   7291  C CD    . GLU D 1 118 ? 99.846  101.893 166.706 1.00 33.70  ? 89  GLU B CD    1 
ATOM   7292  O OE1   . GLU D 1 118 ? 100.532 101.981 167.745 1.00 33.70  ? 89  GLU B OE1   1 
ATOM   7293  O OE2   . GLU D 1 118 ? 99.106  100.918 166.465 1.00 33.70  ? 89  GLU B OE2   1 
ATOM   7294  N N     . LEU D 1 119 ? 103.308 104.713 163.900 1.00 35.27  ? 90  LEU B N     1 
ATOM   7295  C CA    . LEU D 1 119 ? 103.638 104.681 162.475 1.00 35.27  ? 90  LEU B CA    1 
ATOM   7296  C C     . LEU D 1 119 ? 104.760 103.693 162.169 1.00 35.27  ? 90  LEU B C     1 
ATOM   7297  O O     . LEU D 1 119 ? 104.721 103.010 161.139 1.00 35.27  ? 90  LEU B O     1 
ATOM   7298  C CB    . LEU D 1 119 ? 104.021 106.077 161.979 1.00 35.27  ? 90  LEU B CB    1 
ATOM   7299  C CG    . LEU D 1 119 ? 102.940 107.165 161.966 1.00 35.27  ? 90  LEU B CG    1 
ATOM   7300  C CD1   . LEU D 1 119 ? 103.506 108.506 161.521 1.00 35.27  ? 90  LEU B CD1   1 
ATOM   7301  C CD2   . LEU D 1 119 ? 101.763 106.778 161.094 1.00 35.27  ? 90  LEU B CD2   1 
ATOM   7302  N N     . GLY D 1 120 ? 105.761 103.600 163.037 1.00 38.88  ? 91  GLY B N     1 
ATOM   7303  C CA    . GLY D 1 120 ? 106.877 102.718 162.780 1.00 38.88  ? 91  GLY B CA    1 
ATOM   7304  C C     . GLY D 1 120 ? 107.675 102.440 164.033 1.00 38.88  ? 91  GLY B C     1 
ATOM   7305  O O     . GLY D 1 120 ? 107.297 102.839 165.136 1.00 38.88  ? 91  GLY B O     1 
ATOM   7306  N N     . SER D 1 121 ? 108.791 101.730 163.843 1.00 46.08  ? 92  SER B N     1 
ATOM   7307  C CA    . SER D 1 121 ? 109.604 101.294 164.974 1.00 46.08  ? 92  SER B CA    1 
ATOM   7308  C C     . SER D 1 121 ? 110.214 102.479 165.713 1.00 46.08  ? 92  SER B C     1 
ATOM   7309  O O     . SER D 1 121 ? 110.073 102.597 166.936 1.00 46.08  ? 92  SER B O     1 
ATOM   7310  C CB    . SER D 1 121 ? 110.699 100.345 164.489 1.00 46.08  ? 92  SER B CB    1 
ATOM   7311  O OG    . SER D 1 121 ? 111.512 100.967 163.510 1.00 46.08  ? 92  SER B OG    1 
ATOM   7312  N N     . LYS D 1 122 ? 110.904 103.359 164.987 1.00 46.96  ? 93  LYS B N     1 
ATOM   7313  C CA    . LYS D 1 122 ? 111.494 104.578 165.541 1.00 46.96  ? 93  LYS B CA    1 
ATOM   7314  C C     . LYS D 1 122 ? 111.252 105.745 164.590 1.00 46.96  ? 93  LYS B C     1 
ATOM   7315  O O     . LYS D 1 122 ? 112.166 106.490 164.233 1.00 46.96  ? 93  LYS B O     1 
ATOM   7316  C CB    . LYS D 1 122 ? 112.981 104.392 165.845 1.00 46.96  ? 93  LYS B CB    1 
ATOM   7317  C CG    . LYS D 1 122 ? 113.860 103.953 164.655 1.00 46.96  ? 93  LYS B CG    1 
ATOM   7318  C CD    . LYS D 1 122 ? 115.364 103.768 164.990 1.00 46.96  ? 93  LYS B CD    1 
ATOM   7319  C CE    . LYS D 1 122 ? 116.024 104.944 165.727 1.00 46.96  ? 93  LYS B CE    1 
ATOM   7320  N NZ    . LYS D 1 122 ? 117.476 104.719 165.965 1.00 46.96  ? 93  LYS B NZ    1 
ATOM   7321  N N     . VAL D 1 123 ? 110.004 105.896 164.157 1.00 38.12  ? 94  VAL B N     1 
ATOM   7322  C CA    . VAL D 1 123 ? 109.626 107.053 163.338 1.00 38.12  ? 94  VAL B CA    1 
ATOM   7323  C C     . VAL D 1 123 ? 109.831 108.323 164.169 1.00 38.12  ? 94  VAL B C     1 
ATOM   7324  O O     . VAL D 1 123 ? 109.330 108.389 165.308 1.00 38.12  ? 94  VAL B O     1 
ATOM   7325  C CB    . VAL D 1 123 ? 108.163 106.912 162.869 1.00 38.12  ? 94  VAL B CB    1 
ATOM   7326  C CG1   . VAL D 1 123 ? 107.580 108.226 162.371 1.00 38.12  ? 94  VAL B CG1   1 
ATOM   7327  C CG2   . VAL D 1 123 ? 108.065 105.871 161.766 1.00 38.12  ? 94  VAL B CG2   1 
ATOM   7328  N N     . PRO D 1 124 ? 110.566 109.342 163.693 1.00 38.74  ? 95  PRO B N     1 
ATOM   7329  C CA    . PRO D 1 124 ? 110.966 110.427 164.600 1.00 38.74  ? 95  PRO B CA    1 
ATOM   7330  C C     . PRO D 1 124 ? 109.808 111.305 165.047 1.00 38.74  ? 95  PRO B C     1 
ATOM   7331  O O     . PRO D 1 124 ? 108.824 111.500 164.329 1.00 38.74  ? 95  PRO B O     1 
ATOM   7332  C CB    . PRO D 1 124 ? 111.969 111.233 163.767 1.00 38.74  ? 95  PRO B CB    1 
ATOM   7333  C CG    . PRO D 1 124 ? 111.577 110.987 162.390 1.00 38.74  ? 95  PRO B CG    1 
ATOM   7334  C CD    . PRO D 1 124 ? 111.121 109.573 162.344 1.00 38.74  ? 95  PRO B CD    1 
ATOM   7335  N N     . PHE D 1 125 ? 109.955 111.836 166.261 1.00 33.04  ? 96  PHE B N     1 
ATOM   7336  C CA    . PHE D 1 125 ? 108.994 112.732 166.896 1.00 33.04  ? 96  PHE B CA    1 
ATOM   7337  C C     . PHE D 1 125 ? 109.754 113.974 167.331 1.00 33.04  ? 96  PHE B C     1 
ATOM   7338  O O     . PHE D 1 125 ? 110.733 113.869 168.077 1.00 33.04  ? 96  PHE B O     1 
ATOM   7339  C CB    . PHE D 1 125 ? 108.324 112.039 168.089 1.00 33.04  ? 96  PHE B CB    1 
ATOM   7340  C CG    . PHE D 1 125 ? 107.303 112.881 168.806 1.00 33.04  ? 96  PHE B CG    1 
ATOM   7341  C CD1   . PHE D 1 125 ? 106.133 113.269 168.182 1.00 33.04  ? 96  PHE B CD1   1 
ATOM   7342  C CD2   . PHE D 1 125 ? 107.502 113.252 170.122 1.00 33.04  ? 96  PHE B CD2   1 
ATOM   7343  C CE1   . PHE D 1 125 ? 105.194 114.033 168.851 1.00 33.04  ? 96  PHE B CE1   1 
ATOM   7344  C CE2   . PHE D 1 125 ? 106.568 114.016 170.793 1.00 33.04  ? 96  PHE B CE2   1 
ATOM   7345  C CZ    . PHE D 1 125 ? 105.413 114.403 170.157 1.00 33.04  ? 96  PHE B CZ    1 
ATOM   7346  N N     . CYS D 1 126 ? 109.303 115.145 166.869 1.00 37.81  ? 97  CYS B N     1 
ATOM   7347  C CA    . CYS D 1 126 ? 110.008 116.417 167.034 1.00 37.81  ? 97  CYS B CA    1 
ATOM   7348  C C     . CYS D 1 126 ? 109.068 117.398 167.729 1.00 37.81  ? 97  CYS B C     1 
ATOM   7349  O O     . CYS D 1 126 ? 108.483 118.274 167.075 1.00 37.81  ? 97  CYS B O     1 
ATOM   7350  C CB    . CYS D 1 126 ? 110.468 116.974 165.688 1.00 37.81  ? 97  CYS B CB    1 
ATOM   7351  S SG    . CYS D 1 126 ? 111.284 118.588 165.796 1.00 37.81  ? 97  CYS B SG    1 
ATOM   7352  N N     . PRO D 1 127 ? 108.882 117.282 169.044 1.00 33.27  ? 98  PRO B N     1 
ATOM   7353  C CA    . PRO D 1 127 ? 107.962 118.197 169.721 1.00 33.27  ? 98  PRO B CA    1 
ATOM   7354  C C     . PRO D 1 127 ? 108.548 119.593 169.836 1.00 33.27  ? 98  PRO B C     1 
ATOM   7355  O O     . PRO D 1 127 ? 109.764 119.785 169.880 1.00 33.27  ? 98  PRO B O     1 
ATOM   7356  C CB    . PRO D 1 127 ? 107.769 117.555 171.098 1.00 33.27  ? 98  PRO B CB    1 
ATOM   7357  C CG    . PRO D 1 127 ? 109.015 116.815 171.338 1.00 33.27  ? 98  PRO B CG    1 
ATOM   7358  C CD    . PRO D 1 127 ? 109.540 116.374 170.002 1.00 33.27  ? 98  PRO B CD    1 
ATOM   7359  N N     . MET D 1 128 ? 107.656 120.574 169.879 1.00 37.05  ? 99  MET B N     1 
ATOM   7360  C CA    . MET D 1 128 ? 108.040 121.966 170.061 1.00 37.05  ? 99  MET B CA    1 
ATOM   7361  C C     . MET D 1 128 ? 106.836 122.708 170.623 1.00 37.05  ? 99  MET B C     1 
ATOM   7362  O O     . MET D 1 128 ? 105.787 122.113 170.885 1.00 37.05  ? 99  MET B O     1 
ATOM   7363  C CB    . MET D 1 128 ? 108.544 122.575 168.745 1.00 37.05  ? 99  MET B CB    1 
ATOM   7364  C CG    . MET D 1 128 ? 107.561 122.526 167.578 1.00 37.05  ? 99  MET B CG    1 
ATOM   7365  S SD    . MET D 1 128 ? 108.156 123.449 166.149 1.00 37.05  ? 99  MET B SD    1 
ATOM   7366  C CE    . MET D 1 128 ? 107.757 125.124 166.635 1.00 37.05  ? 99  MET B CE    1 
ATOM   7367  N N     . VAL D 1 129 ? 107.006 124.015 170.828 1.00 41.32  ? 100 VAL B N     1 
ATOM   7368  C CA    . VAL D 1 129 ? 105.931 124.915 171.223 1.00 41.32  ? 100 VAL B CA    1 
ATOM   7369  C C     . VAL D 1 129 ? 106.013 126.151 170.341 1.00 41.32  ? 100 VAL B C     1 
ATOM   7370  O O     . VAL D 1 129 ? 107.018 126.399 169.672 1.00 41.32  ? 100 VAL B O     1 
ATOM   7371  C CB    . VAL D 1 129 ? 105.989 125.304 172.718 1.00 41.32  ? 100 VAL B CB    1 
ATOM   7372  C CG1   . VAL D 1 129 ? 105.952 124.058 173.591 1.00 41.32  ? 100 VAL B CG1   1 
ATOM   7373  C CG2   . VAL D 1 129 ? 107.212 126.157 173.028 1.00 41.32  ? 100 VAL B CG2   1 
ATOM   7374  N N     . GLY D 1 130 ? 104.923 126.918 170.327 1.00 44.57  ? 101 GLY B N     1 
ATOM   7375  C CA    . GLY D 1 130 ? 104.891 128.122 169.512 1.00 44.57  ? 101 GLY B CA    1 
ATOM   7376  C C     . GLY D 1 130 ? 105.895 129.163 169.968 1.00 44.57  ? 101 GLY B C     1 
ATOM   7377  O O     . GLY D 1 130 ? 106.535 129.824 169.147 1.00 44.57  ? 101 GLY B O     1 
ATOM   7378  N N     . SER D 1 131 ? 106.069 129.300 171.286 1.00 47.14  ? 102 SER B N     1 
ATOM   7379  C CA    . SER D 1 131 ? 107.029 130.254 171.834 1.00 47.14  ? 102 SER B CA    1 
ATOM   7380  C C     . SER D 1 131 ? 108.464 129.943 171.428 1.00 47.14  ? 102 SER B C     1 
ATOM   7381  O O     . SER D 1 131 ? 109.299 130.853 171.404 1.00 47.14  ? 102 SER B O     1 
ATOM   7382  C CB    . SER D 1 131 ? 106.921 130.279 173.359 1.00 47.14  ? 102 SER B CB    1 
ATOM   7383  O OG    . SER D 1 131 ? 105.585 130.501 173.773 1.00 47.14  ? 102 SER B OG    1 
ATOM   7384  N N     . GLU D 1 132 ? 108.770 128.683 171.105 1.00 47.74  ? 103 GLU B N     1 
ATOM   7385  C CA    . GLU D 1 132 ? 110.085 128.328 170.584 1.00 47.74  ? 103 GLU B CA    1 
ATOM   7386  C C     . GLU D 1 132 ? 110.391 128.994 169.248 1.00 47.74  ? 103 GLU B C     1 
ATOM   7387  O O     . GLU D 1 132 ? 111.568 129.135 168.901 1.00 47.74  ? 103 GLU B O     1 
ATOM   7388  C CB    . GLU D 1 132 ? 110.180 126.812 170.424 1.00 47.74  ? 103 GLU B CB    1 
ATOM   7389  C CG    . GLU D 1 132 ? 111.574 126.281 170.144 1.00 47.74  ? 103 GLU B CG    1 
ATOM   7390  C CD    . GLU D 1 132 ? 111.785 124.882 170.697 1.00 47.74  ? 103 GLU B CD    1 
ATOM   7391  O OE1   . GLU D 1 132 ? 111.603 124.682 171.917 1.00 47.74  ? 103 GLU B OE1   1 
ATOM   7392  O OE2   . GLU D 1 132 ? 112.129 123.979 169.907 1.00 47.74  ? 103 GLU B OE2   1 
ATOM   7393  N N     . VAL D 1 133 ? 109.367 129.385 168.484 1.00 51.57  ? 104 VAL B N     1 
ATOM   7394  C CA    . VAL D 1 133 ? 109.604 129.962 167.165 1.00 51.57  ? 104 VAL B CA    1 
ATOM   7395  C C     . VAL D 1 133 ? 110.289 131.320 167.286 1.00 51.57  ? 104 VAL B C     1 
ATOM   7396  O O     . VAL D 1 133 ? 111.218 131.628 166.530 1.00 51.57  ? 104 VAL B O     1 
ATOM   7397  C CB    . VAL D 1 133 ? 108.276 130.049 166.386 1.00 51.57  ? 104 VAL B CB    1 
ATOM   7398  C CG1   . VAL D 1 133 ? 108.430 130.876 165.121 1.00 51.57  ? 104 VAL B CG1   1 
ATOM   7399  C CG2   . VAL D 1 133 ? 107.771 128.643 166.050 1.00 51.57  ? 104 VAL B CG2   1 
ATOM   7400  N N     . TYR D 1 134 ? 109.852 132.150 168.231 1.00 53.88  ? 105 TYR B N     1 
ATOM   7401  C CA    . TYR D 1 134 ? 110.458 133.465 168.426 1.00 53.88  ? 105 TYR B CA    1 
ATOM   7402  C C     . TYR D 1 134 ? 111.860 133.299 168.996 1.00 53.88  ? 105 TYR B C     1 
ATOM   7403  O O     . TYR D 1 134 ? 112.023 132.981 170.178 1.00 53.88  ? 105 TYR B O     1 
ATOM   7404  C CB    . TYR D 1 134 ? 109.596 134.319 169.349 1.00 53.88  ? 105 TYR B CB    1 
ATOM   7405  C CG    . TYR D 1 134 ? 108.180 134.507 168.866 1.00 53.88  ? 105 TYR B CG    1 
ATOM   7406  C CD1   . TYR D 1 134 ? 107.890 135.396 167.842 1.00 53.88  ? 105 TYR B CD1   1 
ATOM   7407  C CD2   . TYR D 1 134 ? 107.132 133.795 169.431 1.00 53.88  ? 105 TYR B CD2   1 
ATOM   7408  C CE1   . TYR D 1 134 ? 106.597 135.573 167.397 1.00 53.88  ? 105 TYR B CE1   1 
ATOM   7409  C CE2   . TYR D 1 134 ? 105.836 133.965 168.991 1.00 53.88  ? 105 TYR B CE2   1 
ATOM   7410  C CZ    . TYR D 1 134 ? 105.575 134.854 167.974 1.00 53.88  ? 105 TYR B CZ    1 
ATOM   7411  O OH    . TYR D 1 134 ? 104.285 135.027 167.532 1.00 53.88  ? 105 TYR B OH    1 
ATOM   7412  N N     . SER D 1 135 ? 112.870 133.511 168.151 1.00 60.17  ? 106 SER B N     1 
ATOM   7413  C CA    . SER D 1 135 ? 114.275 133.441 168.528 1.00 60.17  ? 106 SER B CA    1 
ATOM   7414  C C     . SER D 1 135 ? 114.994 134.654 167.960 1.00 60.17  ? 106 SER B C     1 
ATOM   7415  O O     . SER D 1 135 ? 114.706 135.086 166.840 1.00 60.17  ? 106 SER B O     1 
ATOM   7416  C CB    . SER D 1 135 ? 114.925 132.153 168.014 1.00 60.17  ? 106 SER B CB    1 
ATOM   7417  O OG    . SER D 1 135 ? 116.221 131.982 168.558 1.00 60.17  ? 106 SER B OG    1 
ATOM   7418  N N     . SER D 1 136 ? 115.920 135.214 168.742 1.00 65.18  ? 107 SER B N     1 
ATOM   7419  C CA    . SER D 1 136 ? 116.647 136.397 168.295 1.00 65.18  ? 107 SER B CA    1 
ATOM   7420  C C     . SER D 1 136 ? 117.732 136.045 167.284 1.00 65.18  ? 107 SER B C     1 
ATOM   7421  O O     . SER D 1 136 ? 117.988 136.818 166.354 1.00 65.18  ? 107 SER B O     1 
ATOM   7422  C CB    . SER D 1 136 ? 117.268 137.118 169.490 1.00 65.18  ? 107 SER B CB    1 
ATOM   7423  O OG    . SER D 1 136 ? 118.526 136.556 169.816 1.00 65.18  ? 107 SER B OG    1 
ATOM   7424  N N     . GLU D 1 137 ? 118.388 134.895 167.460 1.00 65.57  ? 108 GLU B N     1 
ATOM   7425  C CA    . GLU D 1 137 ? 119.516 134.542 166.601 1.00 65.57  ? 108 GLU B CA    1 
ATOM   7426  C C     . GLU D 1 137 ? 119.073 134.275 165.168 1.00 65.57  ? 108 GLU B C     1 
ATOM   7427  O O     . GLU D 1 137 ? 119.744 134.703 164.221 1.00 65.57  ? 108 GLU B O     1 
ATOM   7428  C CB    . GLU D 1 137 ? 120.244 133.320 167.165 1.00 65.57  ? 108 GLU B CB    1 
ATOM   7429  C CG    . GLU D 1 137 ? 120.915 133.543 168.519 1.00 65.57  ? 108 GLU B CG    1 
ATOM   7430  C CD    . GLU D 1 137 ? 122.197 134.356 168.426 1.00 65.57  ? 108 GLU B CD    1 
ATOM   7431  O OE1   . GLU D 1 137 ? 122.539 134.826 167.320 1.00 65.57  ? 108 GLU B OE1   1 
ATOM   7432  O OE2   . GLU D 1 137 ? 122.867 134.523 169.466 1.00 65.57  ? 108 GLU B OE2   1 
ATOM   7433  N N     . VAL D 1 138 ? 117.944 133.580 164.993 1.00 63.52  ? 109 VAL B N     1 
ATOM   7434  C CA    . VAL D 1 138 ? 117.462 133.118 163.698 1.00 63.52  ? 109 VAL B CA    1 
ATOM   7435  C C     . VAL D 1 138 ? 116.008 133.537 163.531 1.00 63.52  ? 109 VAL B C     1 
ATOM   7436  O O     . VAL D 1 138 ? 115.310 133.852 164.496 1.00 63.52  ? 109 VAL B O     1 
ATOM   7437  C CB    . VAL D 1 138 ? 117.608 131.586 163.530 1.00 63.52  ? 109 VAL B CB    1 
ATOM   7438  C CG1   . VAL D 1 138 ? 119.063 131.223 163.289 1.00 63.52  ? 109 VAL B CG1   1 
ATOM   7439  C CG2   . VAL D 1 138 ? 117.083 130.829 164.755 1.00 63.52  ? 109 VAL B CG2   1 
ATOM   7440  N N     . LYS D 1 139 ? 115.559 133.536 162.280 1.00 65.46  ? 110 LYS B N     1 
ATOM   7441  C CA    . LYS D 1 139 ? 114.209 133.971 161.965 1.00 65.46  ? 110 LYS B CA    1 
ATOM   7442  C C     . LYS D 1 139 ? 113.184 132.980 162.510 1.00 65.46  ? 110 LYS B C     1 
ATOM   7443  O O     . LYS D 1 139 ? 113.492 131.823 162.811 1.00 65.46  ? 110 LYS B O     1 
ATOM   7444  C CB    . LYS D 1 139 ? 114.016 134.115 160.452 1.00 65.46  ? 110 LYS B CB    1 
ATOM   7445  C CG    . LYS D 1 139 ? 114.988 135.064 159.737 1.00 65.46  ? 110 LYS B CG    1 
ATOM   7446  C CD    . LYS D 1 139 ? 115.004 134.828 158.223 1.00 65.46  ? 110 LYS B CD    1 
ATOM   7447  C CE    . LYS D 1 139 ? 115.777 133.572 157.813 1.00 65.46  ? 110 LYS B CE    1 
ATOM   7448  N NZ    . LYS D 1 139 ? 116.866 133.878 156.845 1.00 65.46  ? 110 LYS B NZ    1 
ATOM   7449  N N     . LYS D 1 140 ? 111.951 133.467 162.661 1.00 57.54  ? 111 LYS B N     1 
ATOM   7450  C CA    . LYS D 1 140 ? 110.834 132.579 162.983 1.00 57.54  ? 111 LYS B CA    1 
ATOM   7451  C C     . LYS D 1 140 ? 110.657 131.513 161.908 1.00 57.54  ? 111 LYS B C     1 
ATOM   7452  O O     . LYS D 1 140 ? 110.466 130.328 162.216 1.00 57.54  ? 111 LYS B O     1 
ATOM   7453  C CB    . LYS D 1 140 ? 109.526 133.370 163.158 1.00 57.54  ? 111 LYS B CB    1 
ATOM   7454  C CG    . LYS D 1 140 ? 109.220 134.481 162.147 1.00 57.54  ? 111 LYS B CG    1 
ATOM   7455  C CD    . LYS D 1 140 ? 107.821 135.039 162.359 1.00 57.54  ? 111 LYS B CD    1 
ATOM   7456  C CE    . LYS D 1 140 ? 107.820 136.559 162.358 1.00 57.54  ? 111 LYS B CE    1 
ATOM   7457  N NZ    . LYS D 1 140 ? 106.440 137.119 162.372 1.00 57.54  ? 111 LYS B NZ    1 
ATOM   7458  N N     . THR D 1 141 ? 110.733 131.921 160.639 1.00 58.02  ? 112 THR B N     1 
ATOM   7459  C CA    . THR D 1 141 ? 110.589 130.981 159.533 1.00 58.02  ? 112 THR B CA    1 
ATOM   7460  C C     . THR D 1 141 ? 111.711 129.950 159.534 1.00 58.02  ? 112 THR B C     1 
ATOM   7461  O O     . THR D 1 141 ? 111.490 128.782 159.193 1.00 58.02  ? 112 THR B O     1 
ATOM   7462  C CB    . THR D 1 141 ? 110.565 131.750 158.211 1.00 58.02  ? 112 THR B CB    1 
ATOM   7463  O OG1   . THR D 1 141 ? 109.420 132.613 158.180 1.00 58.02  ? 112 THR B OG1   1 
ATOM   7464  C CG2   . THR D 1 141 ? 110.510 130.802 157.030 1.00 58.02  ? 112 THR B CG2   1 
ATOM   7465  N N     . GLU D 1 142 ? 112.921 130.363 159.914 1.00 59.35  ? 113 GLU B N     1 
ATOM   7466  C CA    . GLU D 1 142 ? 114.038 129.427 159.951 1.00 59.35  ? 113 GLU B CA    1 
ATOM   7467  C C     . GLU D 1 142 ? 113.840 128.368 161.029 1.00 59.35  ? 113 GLU B C     1 
ATOM   7468  O O     . GLU D 1 142 ? 114.125 127.190 160.800 1.00 59.35  ? 113 GLU B O     1 
ATOM   7469  C CB    . GLU D 1 142 ? 115.350 130.188 160.167 1.00 59.35  ? 113 GLU B CB    1 
ATOM   7470  C CG    . GLU D 1 142 ? 116.616 129.325 160.305 1.00 59.35  ? 113 GLU B CG    1 
ATOM   7471  C CD    . GLU D 1 142 ? 116.776 128.298 159.199 1.00 59.35  ? 113 GLU B CD    1 
ATOM   7472  O OE1   . GLU D 1 142 ? 116.372 128.587 158.053 1.00 59.35  ? 113 GLU B OE1   1 
ATOM   7473  O OE2   . GLU D 1 142 ? 117.303 127.201 159.477 1.00 59.35  ? 113 GLU B OE2   1 
ATOM   7474  N N     . VAL D 1 143 ? 113.351 128.766 162.207 1.00 55.67  ? 114 VAL B N     1 
ATOM   7475  C CA    . VAL D 1 143 ? 113.078 127.798 163.268 1.00 55.67  ? 114 VAL B CA    1 
ATOM   7476  C C     . VAL D 1 143 ? 111.963 126.853 162.843 1.00 55.67  ? 114 VAL B C     1 
ATOM   7477  O O     . VAL D 1 143 ? 112.014 125.641 163.120 1.00 55.67  ? 114 VAL B O     1 
ATOM   7478  C CB    . VAL D 1 143 ? 112.736 128.524 164.584 1.00 55.67  ? 114 VAL B CB    1 
ATOM   7479  C CG1   . VAL D 1 143 ? 112.256 127.530 165.648 1.00 55.67  ? 114 VAL B CG1   1 
ATOM   7480  C CG2   . VAL D 1 143 ? 113.942 129.312 165.095 1.00 55.67  ? 114 VAL B CG2   1 
ATOM   7481  N N     . LEU D 1 144 ? 110.935 127.396 162.175 1.00 52.01  ? 115 LEU B N     1 
ATOM   7482  C CA    . LEU D 1 144 ? 109.847 126.566 161.665 1.00 52.01  ? 115 LEU B CA    1 
ATOM   7483  C C     . LEU D 1 144 ? 110.362 125.515 160.694 1.00 52.01  ? 115 LEU B C     1 
ATOM   7484  O O     . LEU D 1 144 ? 110.093 124.325 160.869 1.00 52.01  ? 115 LEU B O     1 
ATOM   7485  C CB    . LEU D 1 144 ? 108.791 127.433 160.981 1.00 52.01  ? 115 LEU B CB    1 
ATOM   7486  C CG    . LEU D 1 144 ? 107.762 128.178 161.830 1.00 52.01  ? 115 LEU B CG    1 
ATOM   7487  C CD1   . LEU D 1 144 ? 106.944 129.071 160.921 1.00 52.01  ? 115 LEU B CD1   1 
ATOM   7488  C CD2   . LEU D 1 144 ? 106.852 127.221 162.593 1.00 52.01  ? 115 LEU B CD2   1 
ATOM   7489  N N     . MET D 1 145 ? 111.134 125.932 159.684 1.00 56.01  ? 116 MET B N     1 
ATOM   7490  C CA    . MET D 1 145 ? 111.683 124.972 158.729 1.00 56.01  ? 116 MET B CA    1 
ATOM   7491  C C     . MET D 1 145 ? 112.659 124.005 159.378 1.00 56.01  ? 116 MET B C     1 
ATOM   7492  O O     . MET D 1 145 ? 112.743 122.847 158.955 1.00 56.01  ? 116 MET B O     1 
ATOM   7493  C CB    . MET D 1 145 ? 112.379 125.691 157.569 1.00 56.01  ? 116 MET B CB    1 
ATOM   7494  C CG    . MET D 1 145 ? 111.472 126.246 156.477 1.00 56.01  ? 116 MET B CG    1 
ATOM   7495  S SD    . MET D 1 145 ? 110.319 125.108 155.642 1.00 56.01  ? 116 MET B SD    1 
ATOM   7496  C CE    . MET D 1 145 ? 111.179 123.531 155.617 1.00 56.01  ? 116 MET B CE    1 
ATOM   7497  N N     . GLU D 1 146 ? 113.399 124.451 160.395 1.00 52.65  ? 117 GLU B N     1 
ATOM   7498  C CA    . GLU D 1 146 ? 114.340 123.569 161.073 1.00 52.65  ? 117 GLU B CA    1 
ATOM   7499  C C     . GLU D 1 146 ? 113.605 122.419 161.747 1.00 52.65  ? 117 GLU B C     1 
ATOM   7500  O O     . GLU D 1 146 ? 113.953 121.251 161.553 1.00 52.65  ? 117 GLU B O     1 
ATOM   7501  C CB    . GLU D 1 146 ? 115.163 124.375 162.084 1.00 52.65  ? 117 GLU B CB    1 
ATOM   7502  C CG    . GLU D 1 146 ? 116.235 123.598 162.862 1.00 52.65  ? 117 GLU B CG    1 
ATOM   7503  C CD    . GLU D 1 146 ? 116.903 124.446 163.925 1.00 52.65  ? 117 GLU B CD    1 
ATOM   7504  O OE1   . GLU D 1 146 ? 117.347 125.567 163.600 1.00 52.65  ? 117 GLU B OE1   1 
ATOM   7505  O OE2   . GLU D 1 146 ? 116.982 123.992 165.086 1.00 52.65  ? 117 GLU B OE2   1 
ATOM   7506  N N     . ASN D 1 147 ? 112.552 122.728 162.509 1.00 46.44  ? 118 ASN B N     1 
ATOM   7507  C CA    . ASN D 1 147 ? 111.792 121.655 163.149 1.00 46.44  ? 118 ASN B CA    1 
ATOM   7508  C C     . ASN D 1 147 ? 111.017 120.831 162.120 1.00 46.44  ? 118 ASN B C     1 
ATOM   7509  O O     . ASN D 1 147 ? 110.917 119.600 162.246 1.00 46.44  ? 118 ASN B O     1 
ATOM   7510  C CB    . ASN D 1 147 ? 110.855 122.240 164.201 1.00 46.44  ? 118 ASN B CB    1 
ATOM   7511  C CG    . ASN D 1 147 ? 111.590 122.674 165.451 1.00 46.44  ? 118 ASN B CG    1 
ATOM   7512  O OD1   . ASN D 1 147 ? 111.867 123.857 165.643 1.00 46.44  ? 118 ASN B OD1   1 
ATOM   7513  N ND2   . ASN D 1 147 ? 111.920 121.713 166.305 1.00 46.44  ? 118 ASN B ND2   1 
ATOM   7514  N N     . PHE D 1 148 ? 110.490 121.496 161.084 1.00 49.13  ? 119 PHE B N     1 
ATOM   7515  C CA    . PHE D 1 148 ? 109.721 120.837 160.031 1.00 49.13  ? 119 PHE B CA    1 
ATOM   7516  C C     . PHE D 1 148 ? 110.556 119.788 159.313 1.00 49.13  ? 119 PHE B C     1 
ATOM   7517  O O     . PHE D 1 148 ? 110.079 118.676 159.055 1.00 49.13  ? 119 PHE B O     1 
ATOM   7518  C CB    . PHE D 1 148 ? 109.226 121.915 159.061 1.00 49.13  ? 119 PHE B CB    1 
ATOM   7519  C CG    . PHE D 1 148 ? 108.157 121.480 158.104 1.00 49.13  ? 119 PHE B CG    1 
ATOM   7520  C CD1   . PHE D 1 148 ? 108.474 120.856 156.911 1.00 49.13  ? 119 PHE B CD1   1 
ATOM   7521  C CD2   . PHE D 1 148 ? 106.831 121.774 158.367 1.00 49.13  ? 119 PHE B CD2   1 
ATOM   7522  C CE1   . PHE D 1 148 ? 107.484 120.494 156.022 1.00 49.13  ? 119 PHE B CE1   1 
ATOM   7523  C CE2   . PHE D 1 148 ? 105.839 121.413 157.484 1.00 49.13  ? 119 PHE B CE2   1 
ATOM   7524  C CZ    . PHE D 1 148 ? 106.166 120.780 156.306 1.00 49.13  ? 119 PHE B CZ    1 
ATOM   7525  N N     . ARG D 1 149 ? 111.812 120.113 159.005 1.00 56.11  ? 120 ARG B N     1 
ATOM   7526  C CA    . ARG D 1 149 ? 112.703 119.165 158.353 1.00 56.11  ? 120 ARG B CA    1 
ATOM   7527  C C     . ARG D 1 149 ? 113.350 118.195 159.330 1.00 56.11  ? 120 ARG B C     1 
ATOM   7528  O O     . ARG D 1 149 ? 113.752 117.103 158.917 1.00 56.11  ? 120 ARG B O     1 
ATOM   7529  C CB    . ARG D 1 149 ? 113.797 119.895 157.578 1.00 56.11  ? 120 ARG B CB    1 
ATOM   7530  C CG    . ARG D 1 149 ? 113.294 120.882 156.484 1.00 56.11  ? 120 ARG B CG    1 
ATOM   7531  C CD    . ARG D 1 149 ? 113.508 120.400 155.040 1.00 56.11  ? 120 ARG B CD    1 
ATOM   7532  N NE    . ARG D 1 149 ? 114.866 119.940 154.768 1.00 56.11  ? 120 ARG B NE    1 
ATOM   7533  C CZ    . ARG D 1 149 ? 115.226 119.135 153.776 1.00 56.11  ? 120 ARG B CZ    1 
ATOM   7534  N NH1   . ARG D 1 149 ? 114.389 118.798 152.804 1.00 56.11  ? 120 ARG B NH1   1 
ATOM   7535  N NH2   . ARG D 1 149 ? 116.462 118.648 153.762 1.00 56.11  ? 120 ARG B NH2   1 
ATOM   7536  N N     . ARG D 1 150 ? 113.470 118.562 160.609 1.00 48.47  ? 121 ARG B N     1 
ATOM   7537  C CA    . ARG D 1 150 ? 113.903 117.594 161.607 1.00 48.47  ? 121 ARG B CA    1 
ATOM   7538  C C     . ARG D 1 150 ? 112.893 116.466 161.742 1.00 48.47  ? 121 ARG B C     1 
ATOM   7539  O O     . ARG D 1 150 ? 113.271 115.321 162.012 1.00 48.47  ? 121 ARG B O     1 
ATOM   7540  C CB    . ARG D 1 150 ? 114.099 118.287 162.956 1.00 48.47  ? 121 ARG B CB    1 
ATOM   7541  C CG    . ARG D 1 150 ? 114.904 117.494 163.984 1.00 48.47  ? 121 ARG B CG    1 
ATOM   7542  C CD    . ARG D 1 150 ? 116.362 117.926 164.020 1.00 48.47  ? 121 ARG B CD    1 
ATOM   7543  N NE    . ARG D 1 150 ? 116.526 119.259 164.595 1.00 48.47  ? 121 ARG B NE    1 
ATOM   7544  C CZ    . ARG D 1 150 ? 117.677 119.802 164.974 1.00 48.47  ? 121 ARG B CZ    1 
ATOM   7545  N NH1   . ARG D 1 150 ? 118.832 119.160 164.856 1.00 48.47  ? 121 ARG B NH1   1 
ATOM   7546  N NH2   . ARG D 1 150 ? 117.673 121.029 165.486 1.00 48.47  ? 121 ARG B NH2   1 
ATOM   7547  N N     . ALA D 1 151 ? 111.605 116.771 161.561 1.00 43.38  ? 122 ALA B N     1 
ATOM   7548  C CA    . ALA D 1 151 ? 110.578 115.746 161.690 1.00 43.38  ? 122 ALA B CA    1 
ATOM   7549  C C     . ALA D 1 151 ? 110.639 114.681 160.597 1.00 43.38  ? 122 ALA B C     1 
ATOM   7550  O O     . ALA D 1 151 ? 110.130 113.580 160.812 1.00 43.38  ? 122 ALA B O     1 
ATOM   7551  C CB    . ALA D 1 151 ? 109.197 116.397 161.695 1.00 43.38  ? 122 ALA B CB    1 
ATOM   7552  N N     . ILE D 1 152 ? 111.243 114.963 159.440 1.00 49.27  ? 123 ILE B N     1 
ATOM   7553  C CA    . ILE D 1 152 ? 111.256 114.018 158.321 1.00 49.27  ? 123 ILE B CA    1 
ATOM   7554  C C     . ILE D 1 152 ? 112.395 113.032 158.540 1.00 49.27  ? 123 ILE B C     1 
ATOM   7555  O O     . ILE D 1 152 ? 113.481 113.421 158.985 1.00 49.27  ? 123 ILE B O     1 
ATOM   7556  C CB    . ILE D 1 152 ? 111.402 114.736 156.960 1.00 49.27  ? 123 ILE B CB    1 
ATOM   7557  C CG1   . ILE D 1 152 ? 110.302 115.790 156.717 1.00 49.27  ? 123 ILE B CG1   1 
ATOM   7558  C CG2   . ILE D 1 152 ? 111.338 113.708 155.817 1.00 49.27  ? 123 ILE B CG2   1 
ATOM   7559  C CD1   . ILE D 1 152 ? 110.681 116.855 155.693 1.00 49.27  ? 123 ILE B CD1   1 
ATOM   7560  N N     . GLY D 1 153 ? 112.145 111.757 158.228 1.00 54.18  ? 124 GLY B N     1 
ATOM   7561  C CA    . GLY D 1 153 ? 113.152 110.713 158.342 1.00 54.18  ? 124 GLY B CA    1 
ATOM   7562  C C     . GLY D 1 153 ? 113.378 110.002 157.020 1.00 54.18  ? 124 GLY B C     1 
ATOM   7563  O O     . GLY D 1 153 ? 112.449 109.816 156.232 1.00 54.18  ? 124 GLY B O     1 
ATOM   7564  N N     . LEU D 1 154 ? 114.625 109.578 156.798 1.00 63.18  ? 125 LEU B N     1 
ATOM   7565  C CA    . LEU D 1 154 ? 115.037 108.862 155.595 1.00 63.18  ? 125 LEU B CA    1 
ATOM   7566  C C     . LEU D 1 154 ? 115.962 107.726 155.995 1.00 63.18  ? 125 LEU B C     1 
ATOM   7567  O O     . LEU D 1 154 ? 116.916 107.953 156.743 1.00 63.18  ? 125 LEU B O     1 
ATOM   7568  C CB    . LEU D 1 154 ? 115.770 109.797 154.625 1.00 63.18  ? 125 LEU B CB    1 
ATOM   7569  C CG    . LEU D 1 154 ? 115.797 109.510 153.118 1.00 63.18  ? 125 LEU B CG    1 
ATOM   7570  C CD1   . LEU D 1 154 ? 114.416 109.407 152.488 1.00 63.18  ? 125 LEU B CD1   1 
ATOM   7571  C CD2   . LEU D 1 154 ? 116.621 110.577 152.411 1.00 63.18  ? 125 LEU B CD2   1 
ATOM   7572  N N     . ARG D 1 155 ? 115.693 106.519 155.485 1.00 71.68  ? 126 ARG B N     1 
ATOM   7573  C CA    . ARG D 1 155 ? 116.560 105.361 155.669 1.00 71.68  ? 126 ARG B CA    1 
ATOM   7574  C C     . ARG D 1 155 ? 117.152 104.949 154.329 1.00 71.68  ? 126 ARG B C     1 
ATOM   7575  O O     . ARG D 1 155 ? 116.450 104.903 153.312 1.00 71.68  ? 126 ARG B O     1 
ATOM   7576  C CB    . ARG D 1 155 ? 115.811 104.191 156.340 1.00 71.68  ? 126 ARG B CB    1 
ATOM   7577  C CG    . ARG D 1 155 ? 114.659 103.551 155.553 1.00 71.68  ? 126 ARG B CG    1 
ATOM   7578  C CD    . ARG D 1 155 ? 114.144 102.278 156.229 1.00 71.68  ? 126 ARG B CD    1 
ATOM   7579  N NE    . ARG D 1 155 ? 113.882 102.438 157.657 1.00 71.68  ? 126 ARG B NE    1 
ATOM   7580  C CZ    . ARG D 1 155 ? 113.421 101.490 158.467 1.00 71.68  ? 126 ARG B CZ    1 
ATOM   7581  N NH1   . ARG D 1 155 ? 113.141 100.267 158.033 1.00 71.68  ? 126 ARG B NH1   1 
ATOM   7582  N NH2   . ARG D 1 155 ? 113.236 101.774 159.753 1.00 71.68  ? 126 ARG B NH2   1 
ATOM   7583  N N     . ILE D 1 156 ? 118.452 104.653 154.347 1.00 79.21  ? 127 ILE B N     1 
ATOM   7584  C CA    . ILE D 1 156 ? 119.243 104.377 153.154 1.00 79.21  ? 127 ILE B CA    1 
ATOM   7585  C C     . ILE D 1 156 ? 119.985 103.066 153.360 1.00 79.21  ? 127 ILE B C     1 
ATOM   7586  O O     . ILE D 1 156 ? 120.522 102.809 154.445 1.00 79.21  ? 127 ILE B O     1 
ATOM   7587  C CB    . ILE D 1 156 ? 120.228 105.531 152.838 1.00 79.21  ? 127 ILE B CB    1 
ATOM   7588  C CG1   . ILE D 1 156 ? 121.057 105.933 154.073 1.00 79.21  ? 127 ILE B CG1   1 
ATOM   7589  C CG2   . ILE D 1 156 ? 119.468 106.751 152.303 1.00 79.21  ? 127 ILE B CG2   1 
ATOM   7590  C CD1   . ILE D 1 156 ? 122.117 106.980 153.790 1.00 79.21  ? 127 ILE B CD1   1 
ATOM   7591  N N     . LYS D 1 157 ? 119.998 102.234 152.320 1.00 86.60  ? 128 LYS B N     1 
ATOM   7592  C CA    . LYS D 1 157 ? 120.686 100.945 152.342 1.00 86.60  ? 128 LYS B CA    1 
ATOM   7593  C C     . LYS D 1 157 ? 122.152 101.097 151.939 1.00 86.60  ? 128 LYS B C     1 
ATOM   7594  O O     . LYS D 1 157 ? 122.497 101.933 151.103 1.00 86.60  ? 128 LYS B O     1 
ATOM   7595  C CB    . LYS D 1 157 ? 119.976 99.939  151.420 1.00 86.60  ? 128 LYS B CB    1 
ATOM   7596  C CG    . LYS D 1 157 ? 120.009 100.278 149.919 1.00 86.60  ? 128 LYS B CG    1 
ATOM   7597  C CD    . LYS D 1 157 ? 119.163 99.320  149.078 1.00 86.60  ? 128 LYS B CD    1 
ATOM   7598  C CE    . LYS D 1 157 ? 117.663 99.541  149.255 1.00 86.60  ? 128 LYS B CE    1 
ATOM   7599  N NZ    . LYS D 1 157 ? 116.870 98.856  148.196 1.00 86.60  ? 128 LYS B NZ    1 
ATOM   7600  N N     . VAL D 1 267 ? 121.349 98.930  156.557 1.00 85.52  ? 238 VAL B N     1 
ATOM   7601  C CA    . VAL D 1 267 ? 120.510 100.105 156.353 1.00 85.52  ? 238 VAL B CA    1 
ATOM   7602  C C     . VAL D 1 267 ? 120.651 101.007 157.572 1.00 85.52  ? 238 VAL B C     1 
ATOM   7603  O O     . VAL D 1 267 ? 120.738 100.510 158.695 1.00 85.52  ? 238 VAL B O     1 
ATOM   7604  C CB    . VAL D 1 267 ? 119.026 99.710  156.098 1.00 85.52  ? 238 VAL B CB    1 
ATOM   7605  C CG1   . VAL D 1 267 ? 118.106 100.935 156.138 1.00 85.52  ? 238 VAL B CG1   1 
ATOM   7606  C CG2   . VAL D 1 267 ? 118.870 98.971  154.759 1.00 85.52  ? 238 VAL B CG2   1 
ATOM   7607  N N     . GLN D 1 268 ? 120.684 102.324 157.345 1.00 81.65  ? 239 GLN B N     1 
ATOM   7608  C CA    . GLN D 1 268 ? 120.812 103.302 158.419 1.00 81.65  ? 239 GLN B CA    1 
ATOM   7609  C C     . GLN D 1 268 ? 119.881 104.477 158.156 1.00 81.65  ? 239 GLN B C     1 
ATOM   7610  O O     . GLN D 1 268 ? 119.610 104.828 157.005 1.00 81.65  ? 239 GLN B O     1 
ATOM   7611  C CB    . GLN D 1 268 ? 122.271 103.777 158.574 1.00 81.65  ? 239 GLN B CB    1 
ATOM   7612  C CG    . GLN D 1 268 ? 122.816 104.663 157.449 1.00 81.65  ? 239 GLN B CG    1 
ATOM   7613  C CD    . GLN D 1 268 ? 124.296 104.956 157.606 1.00 81.65  ? 239 GLN B CD    1 
ATOM   7614  O OE1   . GLN D 1 268 ? 125.038 104.177 158.204 1.00 81.65  ? 239 GLN B OE1   1 
ATOM   7615  N NE2   . GLN D 1 268 ? 124.732 106.089 157.069 1.00 81.65  ? 239 GLN B NE2   1 
ATOM   7616  N N     . ASP D 1 269 ? 119.423 105.093 159.246 1.00 69.13  ? 240 ASP B N     1 
ATOM   7617  C CA    . ASP D 1 269 ? 118.431 106.159 159.233 1.00 69.13  ? 240 ASP B CA    1 
ATOM   7618  C C     . ASP D 1 269 ? 119.073 107.496 159.580 1.00 69.13  ? 240 ASP B C     1 
ATOM   7619  O O     . ASP D 1 269 ? 120.109 107.562 160.246 1.00 69.13  ? 240 ASP B O     1 
ATOM   7620  C CB    . ASP D 1 269 ? 117.291 105.862 160.216 1.00 69.13  ? 240 ASP B CB    1 
ATOM   7621  C CG    . ASP D 1 269 ? 117.767 105.758 161.652 1.00 69.13  ? 240 ASP B CG    1 
ATOM   7622  O OD1   . ASP D 1 269 ? 118.974 105.517 161.866 1.00 69.13  ? 240 ASP B OD1   1 
ATOM   7623  O OD2   . ASP D 1 269 ? 116.933 105.914 162.567 1.00 69.13  ? 240 ASP B OD2   1 
ATOM   7624  N N     . VAL D 1 270 ? 118.436 108.570 159.113 1.00 61.60  ? 241 VAL B N     1 
ATOM   7625  C CA    . VAL D 1 270 ? 118.937 109.921 159.327 1.00 61.60  ? 241 VAL B CA    1 
ATOM   7626  C C     . VAL D 1 270 ? 117.796 110.893 159.069 1.00 61.60  ? 241 VAL B C     1 
ATOM   7627  O O     . VAL D 1 270 ? 116.926 110.644 158.230 1.00 61.60  ? 241 VAL B O     1 
ATOM   7628  C CB    . VAL D 1 270 ? 120.160 110.216 158.419 1.00 61.60  ? 241 VAL B CB    1 
ATOM   7629  C CG1   . VAL D 1 270 ? 119.738 110.364 156.956 1.00 61.60  ? 241 VAL B CG1   1 
ATOM   7630  C CG2   . VAL D 1 270 ? 120.898 111.460 158.895 1.00 61.60  ? 241 VAL B CG2   1 
ATOM   7631  N N     . THR D 1 271 ? 117.807 112.010 159.791 1.00 56.25  ? 242 THR B N     1 
ATOM   7632  C CA    . THR D 1 271 ? 116.850 113.079 159.560 1.00 56.25  ? 242 THR B CA    1 
ATOM   7633  C C     . THR D 1 271 ? 117.299 113.941 158.386 1.00 56.25  ? 242 THR B C     1 
ATOM   7634  O O     . THR D 1 271 ? 118.486 114.028 158.065 1.00 56.25  ? 242 THR B O     1 
ATOM   7635  C CB    . THR D 1 271 ? 116.691 113.955 160.804 1.00 56.25  ? 242 THR B CB    1 
ATOM   7636  O OG1   . THR D 1 271 ? 117.848 114.788 160.954 1.00 56.25  ? 242 THR B OG1   1 
ATOM   7637  C CG2   . THR D 1 271 ? 116.503 113.105 162.056 1.00 56.25  ? 242 THR B CG2   1 
ATOM   7638  N N     . LEU D 1 272 ? 116.327 114.591 157.743 1.00 56.25  ? 243 LEU B N     1 
ATOM   7639  C CA    . LEU D 1 272 ? 116.651 115.503 156.653 1.00 56.25  ? 243 LEU B CA    1 
ATOM   7640  C C     . LEU D 1 272 ? 117.325 116.778 157.139 1.00 56.25  ? 243 LEU B C     1 
ATOM   7641  O O     . LEU D 1 272 ? 117.948 117.472 156.332 1.00 56.25  ? 243 LEU B O     1 
ATOM   7642  C CB    . LEU D 1 272 ? 115.388 115.873 155.865 1.00 56.25  ? 243 LEU B CB    1 
ATOM   7643  C CG    . LEU D 1 272 ? 114.758 114.947 154.809 1.00 56.25  ? 243 LEU B CG    1 
ATOM   7644  C CD1   . LEU D 1 272 ? 113.884 115.771 153.877 1.00 56.25  ? 243 LEU B CD1   1 
ATOM   7645  C CD2   . LEU D 1 272 ? 115.747 114.139 153.974 1.00 56.25  ? 243 LEU B CD2   1 
ATOM   7646  N N     . GLN D 1 273 ? 117.213 117.113 158.428 1.00 55.61  ? 244 GLN B N     1 
ATOM   7647  C CA    . GLN D 1 273 ? 117.935 118.272 158.941 1.00 55.61  ? 244 GLN B CA    1 
ATOM   7648  C C     . GLN D 1 273 ? 119.441 118.051 158.893 1.00 55.61  ? 244 GLN B C     1 
ATOM   7649  O O     . GLN D 1 273 ? 120.196 119.009 158.699 1.00 55.61  ? 244 GLN B O     1 
ATOM   7650  C CB    . GLN D 1 273 ? 117.468 118.588 160.369 1.00 55.61  ? 244 GLN B CB    1 
ATOM   7651  C CG    . GLN D 1 273 ? 118.283 119.634 161.172 1.00 55.61  ? 244 GLN B CG    1 
ATOM   7652  C CD    . GLN D 1 273 ? 118.322 121.019 160.539 1.00 55.61  ? 244 GLN B CD    1 
ATOM   7653  O OE1   . GLN D 1 273 ? 117.748 121.259 159.479 1.00 55.61  ? 244 GLN B OE1   1 
ATOM   7654  N NE2   . GLN D 1 273 ? 119.019 121.938 161.195 1.00 55.61  ? 244 GLN B NE2   1 
ATOM   7655  N N     . ASP D 1 274 ? 119.895 116.807 159.074 1.00 58.75  ? 245 ASP B N     1 
ATOM   7656  C CA    . ASP D 1 274 ? 121.323 116.519 158.969 1.00 58.75  ? 245 ASP B CA    1 
ATOM   7657  C C     . ASP D 1 274 ? 121.832 116.786 157.559 1.00 58.75  ? 245 ASP B C     1 
ATOM   7658  O O     . ASP D 1 274 ? 122.898 117.386 157.378 1.00 58.75  ? 245 ASP B O     1 
ATOM   7659  C CB    . ASP D 1 274 ? 121.600 115.070 159.370 1.00 58.75  ? 245 ASP B CB    1 
ATOM   7660  C CG    . ASP D 1 274 ? 121.084 114.737 160.755 1.00 58.75  ? 245 ASP B CG    1 
ATOM   7661  O OD1   . ASP D 1 274 ? 121.463 115.437 161.718 1.00 58.75  ? 245 ASP B OD1   1 
ATOM   7662  O OD2   . ASP D 1 274 ? 120.296 113.777 160.880 1.00 58.75  ? 245 ASP B OD2   1 
ATOM   7663  N N     . LEU D 1 275 ? 121.075 116.360 156.548 1.00 58.05  ? 246 LEU B N     1 
ATOM   7664  C CA    . LEU D 1 275 ? 121.438 116.668 155.169 1.00 58.05  ? 246 LEU B CA    1 
ATOM   7665  C C     . LEU D 1 275 ? 121.339 118.164 154.896 1.00 58.05  ? 246 LEU B C     1 
ATOM   7666  O O     . LEU D 1 275 ? 122.136 118.716 154.131 1.00 58.05  ? 246 LEU B O     1 
ATOM   7667  C CB    . LEU D 1 275 ? 120.539 115.895 154.202 1.00 58.05  ? 246 LEU B CB    1 
ATOM   7668  C CG    . LEU D 1 275 ? 120.880 114.432 153.904 1.00 58.05  ? 246 LEU B CG    1 
ATOM   7669  C CD1   . LEU D 1 275 ? 120.752 113.550 155.138 1.00 58.05  ? 246 LEU B CD1   1 
ATOM   7670  C CD2   . LEU D 1 275 ? 119.987 113.918 152.786 1.00 58.05  ? 246 LEU B CD2   1 
ATOM   7671  N N     . ASP D 1 276 ? 120.361 118.835 155.509 1.00 59.89  ? 247 ASP B N     1 
ATOM   7672  C CA    . ASP D 1 276 ? 120.169 120.260 155.263 1.00 59.89  ? 247 ASP B CA    1 
ATOM   7673  C C     . ASP D 1 276 ? 121.310 121.085 155.845 1.00 59.89  ? 247 ASP B C     1 
ATOM   7674  O O     . ASP D 1 276 ? 121.713 122.096 155.258 1.00 59.89  ? 247 ASP B O     1 
ATOM   7675  C CB    . ASP D 1 276 ? 118.830 120.713 155.852 1.00 59.89  ? 247 ASP B CB    1 
ATOM   7676  C CG    . ASP D 1 276 ? 118.195 121.849 155.072 1.00 59.89  ? 247 ASP B CG    1 
ATOM   7677  O OD1   . ASP D 1 276 ? 118.039 121.723 153.839 1.00 59.89  ? 247 ASP B OD1   1 
ATOM   7678  O OD2   . ASP D 1 276 ? 117.834 122.869 155.696 1.00 59.89  ? 247 ASP B OD2   1 
ATOM   7679  N N     . ALA D 1 277 ? 121.838 120.673 156.999 1.00 56.54  ? 248 ALA B N     1 
ATOM   7680  C CA    . ALA D 1 277 ? 122.876 121.422 157.699 1.00 56.54  ? 248 ALA B CA    1 
ATOM   7681  C C     . ALA D 1 277 ? 124.279 121.045 157.234 1.00 56.54  ? 248 ALA B C     1 
ATOM   7682  O O     . ALA D 1 277 ? 125.099 121.927 156.964 1.00 56.54  ? 248 ALA B O     1 
ATOM   7683  C CB    . ALA D 1 277 ? 122.750 121.199 159.208 1.00 56.54  ? 248 ALA B CB    1 
ATOM   7684  N N     . ALA D 1 278 ? 124.575 119.744 157.146 1.00 54.98  ? 249 ALA B N     1 
ATOM   7685  C CA    . ALA D 1 278 ? 125.917 119.314 156.763 1.00 54.98  ? 249 ALA B CA    1 
ATOM   7686  C C     . ALA D 1 278 ? 126.221 119.676 155.315 1.00 54.98  ? 249 ALA B C     1 
ATOM   7687  O O     . ALA D 1 278 ? 127.268 120.265 155.019 1.00 54.98  ? 249 ALA B O     1 
ATOM   7688  C CB    . ALA D 1 278 ? 126.065 117.809 156.984 1.00 54.98  ? 249 ALA B CB    1 
ATOM   7689  N N     . ASN D 1 279 ? 125.309 119.346 154.401 1.00 55.03  ? 250 ASN B N     1 
ATOM   7690  C CA    . ASN D 1 279 ? 125.466 119.651 152.978 1.00 55.03  ? 250 ASN B CA    1 
ATOM   7691  C C     . ASN D 1 279 ? 124.877 121.029 152.665 1.00 55.03  ? 250 ASN B C     1 
ATOM   7692  O O     . ASN D 1 279 ? 123.985 121.189 151.833 1.00 55.03  ? 250 ASN B O     1 
ATOM   7693  C CB    . ASN D 1 279 ? 124.810 118.563 152.137 1.00 55.03  ? 250 ASN B CB    1 
ATOM   7694  C CG    . ASN D 1 279 ? 125.217 117.167 152.572 1.00 55.03  ? 250 ASN B CG    1 
ATOM   7695  O OD1   . ASN D 1 279 ? 125.311 116.882 153.766 1.00 55.03  ? 250 ASN B OD1   1 
ATOM   7696  N ND2   . ASN D 1 279 ? 125.454 116.288 151.604 1.00 55.03  ? 250 ASN B ND2   1 
ATOM   7697  N N     . ALA D 1 280 ? 125.404 122.036 153.356 1.00 59.67  ? 251 ALA B N     1 
ATOM   7698  C CA    . ALA D 1 280 ? 124.906 123.401 153.233 1.00 59.67  ? 251 ALA B CA    1 
ATOM   7699  C C     . ALA D 1 280 ? 125.364 124.040 151.928 1.00 59.67  ? 251 ALA B C     1 
ATOM   7700  O O     . ALA D 1 280 ? 126.043 123.413 151.116 1.00 59.67  ? 251 ALA B O     1 
ATOM   7701  C CB    . ALA D 1 280 ? 125.362 124.237 154.417 1.00 59.67  ? 251 ALA B CB    1 
ATOM   7702  N N     . LYS D 1 306 ? 117.189 128.048 148.211 1.00 74.36  ? 277 LYS B N     1 
ATOM   7703  C CA    . LYS D 1 306 ? 117.865 127.194 147.238 1.00 74.36  ? 277 LYS B CA    1 
ATOM   7704  C C     . LYS D 1 306 ? 118.400 125.918 147.881 1.00 74.36  ? 277 LYS B C     1 
ATOM   7705  O O     . LYS D 1 306 ? 118.457 124.875 147.233 1.00 74.36  ? 277 LYS B O     1 
ATOM   7706  C CB    . LYS D 1 306 ? 119.012 127.948 146.558 1.00 74.36  ? 277 LYS B CB    1 
ATOM   7707  C CG    . LYS D 1 306 ? 118.584 129.156 145.728 1.00 74.36  ? 277 LYS B CG    1 
ATOM   7708  C CD    . LYS D 1 306 ? 118.342 128.772 144.274 1.00 74.36  ? 277 LYS B CD    1 
ATOM   7709  C CE    . LYS D 1 306 ? 117.893 129.961 143.438 1.00 74.36  ? 277 LYS B CE    1 
ATOM   7710  N NZ    . LYS D 1 306 ? 118.905 131.053 143.395 1.00 74.36  ? 277 LYS B NZ    1 
ATOM   7711  N N     . LEU D 1 307 ? 118.801 126.005 149.152 1.00 69.80  ? 278 LEU B N     1 
ATOM   7712  C CA    . LEU D 1 307 ? 119.258 124.811 149.861 1.00 69.80  ? 278 LEU B CA    1 
ATOM   7713  C C     . LEU D 1 307 ? 118.115 123.818 150.023 1.00 69.80  ? 278 LEU B C     1 
ATOM   7714  O O     . LEU D 1 307 ? 118.280 122.615 149.780 1.00 69.80  ? 278 LEU B O     1 
ATOM   7715  C CB    . LEU D 1 307 ? 119.844 125.166 151.237 1.00 69.80  ? 278 LEU B CB    1 
ATOM   7716  C CG    . LEU D 1 307 ? 120.569 126.483 151.552 1.00 69.80  ? 278 LEU B CG    1 
ATOM   7717  C CD1   . LEU D 1 307 ? 120.730 126.644 153.057 1.00 69.80  ? 278 LEU B CD1   1 
ATOM   7718  C CD2   . LEU D 1 307 ? 121.916 126.532 150.856 1.00 69.80  ? 278 LEU B CD2   1 
ATOM   7719  N N     . ARG D 1 308 ? 116.940 124.318 150.418 1.00 66.28  ? 279 ARG B N     1 
ATOM   7720  C CA    . ARG D 1 308 ? 115.776 123.457 150.595 1.00 66.28  ? 279 ARG B CA    1 
ATOM   7721  C C     . ARG D 1 308 ? 115.351 122.837 149.270 1.00 66.28  ? 279 ARG B C     1 
ATOM   7722  O O     . ARG D 1 308 ? 115.110 121.630 149.188 1.00 66.28  ? 279 ARG B O     1 
ATOM   7723  C CB    . ARG D 1 308 ? 114.612 124.249 151.203 1.00 66.28  ? 279 ARG B CB    1 
ATOM   7724  C CG    . ARG D 1 308 ? 114.890 124.973 152.527 1.00 66.28  ? 279 ARG B CG    1 
ATOM   7725  C CD    . ARG D 1 308 ? 114.975 124.011 153.701 1.00 66.28  ? 279 ARG B CD    1 
ATOM   7726  N NE    . ARG D 1 308 ? 116.052 124.362 154.623 1.00 66.28  ? 279 ARG B NE    1 
ATOM   7727  C CZ    . ARG D 1 308 ? 116.026 125.370 155.490 1.00 66.28  ? 279 ARG B CZ    1 
ATOM   7728  N NH1   . ARG D 1 308 ? 114.991 126.195 155.582 1.00 66.28  ? 279 ARG B NH1   1 
ATOM   7729  N NH2   . ARG D 1 308 ? 117.071 125.560 156.289 1.00 66.28  ? 279 ARG B NH2   1 
ATOM   7730  N N     . GLN D 1 309 ? 115.276 123.648 148.213 1.00 74.04  ? 280 GLN B N     1 
ATOM   7731  C CA    . GLN D 1 309 ? 114.853 123.132 146.914 1.00 74.04  ? 280 GLN B CA    1 
ATOM   7732  C C     . GLN D 1 309 ? 115.879 122.162 146.337 1.00 74.04  ? 280 GLN B C     1 
ATOM   7733  O O     . GLN D 1 309 ? 115.510 121.117 145.786 1.00 74.04  ? 280 GLN B O     1 
ATOM   7734  C CB    . GLN D 1 309 ? 114.607 124.292 145.949 1.00 74.04  ? 280 GLN B CB    1 
ATOM   7735  C CG    . GLN D 1 309 ? 113.467 125.211 146.367 1.00 74.04  ? 280 GLN B CG    1 
ATOM   7736  C CD    . GLN D 1 309 ? 113.279 126.378 145.416 1.00 74.04  ? 280 GLN B CD    1 
ATOM   7737  O OE1   . GLN D 1 309 ? 114.243 126.898 144.855 1.00 74.04  ? 280 GLN B OE1   1 
ATOM   7738  N NE2   . GLN D 1 309 ? 112.032 126.793 145.231 1.00 74.04  ? 280 GLN B NE2   1 
ATOM   7739  N N     . GLU D 1 310 ? 117.170 122.483 146.463 1.00 73.75  ? 281 GLU B N     1 
ATOM   7740  C CA    . GLU D 1 310 ? 118.214 121.620 145.917 1.00 73.75  ? 281 GLU B CA    1 
ATOM   7741  C C     . GLU D 1 310 ? 118.247 120.276 146.636 1.00 73.75  ? 281 GLU B C     1 
ATOM   7742  O O     . GLU D 1 310 ? 118.294 119.217 145.996 1.00 73.75  ? 281 GLU B O     1 
ATOM   7743  C CB    . GLU D 1 310 ? 119.571 122.327 146.014 1.00 73.75  ? 281 GLU B CB    1 
ATOM   7744  C CG    . GLU D 1 310 ? 120.770 121.582 145.408 1.00 73.75  ? 281 GLU B CG    1 
ATOM   7745  C CD    . GLU D 1 310 ? 120.633 121.343 143.918 1.00 73.75  ? 281 GLU B CD    1 
ATOM   7746  O OE1   . GLU D 1 310 ? 119.856 122.070 143.266 1.00 73.75  ? 281 GLU B OE1   1 
ATOM   7747  O OE2   . GLU D 1 310 ? 121.303 120.424 143.400 1.00 73.75  ? 281 GLU B OE2   1 
ATOM   7748  N N     . ILE D 1 311 ? 118.217 120.297 147.971 1.00 65.44  ? 282 ILE B N     1 
ATOM   7749  C CA    . ILE D 1 311 ? 118.234 119.039 148.705 1.00 65.44  ? 282 ILE B CA    1 
ATOM   7750  C C     . ILE D 1 311 ? 116.932 118.269 148.500 1.00 65.44  ? 282 ILE B C     1 
ATOM   7751  O O     . ILE D 1 311 ? 116.937 117.034 148.504 1.00 65.44  ? 282 ILE B O     1 
ATOM   7752  C CB    . ILE D 1 311 ? 118.560 119.298 150.194 1.00 65.44  ? 282 ILE B CB    1 
ATOM   7753  C CG1   . ILE D 1 311 ? 119.186 118.059 150.852 1.00 65.44  ? 282 ILE B CG1   1 
ATOM   7754  C CG2   . ILE D 1 311 ? 117.355 119.808 150.969 1.00 65.44  ? 282 ILE B CG2   1 
ATOM   7755  C CD1   . ILE D 1 311 ? 120.641 117.805 150.487 1.00 65.44  ? 282 ILE B CD1   1 
ATOM   7756  N N     . ASN D 1 312 ? 115.804 118.964 148.302 1.00 69.64  ? 283 ASN B N     1 
ATOM   7757  C CA    . ASN D 1 312 ? 114.562 118.266 147.979 1.00 69.64  ? 283 ASN B CA    1 
ATOM   7758  C C     . ASN D 1 312 ? 114.666 117.564 146.633 1.00 69.64  ? 283 ASN B C     1 
ATOM   7759  O O     . ASN D 1 312 ? 114.177 116.442 146.474 1.00 69.64  ? 283 ASN B O     1 
ATOM   7760  C CB    . ASN D 1 312 ? 113.377 119.234 147.969 1.00 69.64  ? 283 ASN B CB    1 
ATOM   7761  C CG    . ASN D 1 312 ? 112.607 119.228 149.274 1.00 69.64  ? 283 ASN B CG    1 
ATOM   7762  O OD1   . ASN D 1 312 ? 111.839 118.308 149.549 1.00 69.64  ? 283 ASN B OD1   1 
ATOM   7763  N ND2   . ASN D 1 312 ? 112.812 120.257 150.089 1.00 69.64  ? 283 ASN B ND2   1 
ATOM   7764  N N     . LYS D 1 313 ? 115.296 118.216 145.652 1.00 73.14  ? 284 LYS B N     1 
ATOM   7765  C CA    . LYS D 1 313 ? 115.542 117.572 144.365 1.00 73.14  ? 284 LYS B CA    1 
ATOM   7766  C C     . LYS D 1 313 ? 116.434 116.347 144.525 1.00 73.14  ? 284 LYS B C     1 
ATOM   7767  O O     . LYS D 1 313 ? 116.197 115.309 143.894 1.00 73.14  ? 284 LYS B O     1 
ATOM   7768  C CB    . LYS D 1 313 ? 116.182 118.568 143.397 1.00 73.14  ? 284 LYS B CB    1 
ATOM   7769  C CG    . LYS D 1 313 ? 115.211 119.574 142.789 1.00 73.14  ? 284 LYS B CG    1 
ATOM   7770  C CD    . LYS D 1 313 ? 114.929 119.288 141.315 1.00 73.14  ? 284 LYS B CD    1 
ATOM   7771  C CE    . LYS D 1 313 ? 116.083 119.722 140.414 1.00 73.14  ? 284 LYS B CE    1 
ATOM   7772  N NZ    . LYS D 1 313 ? 115.707 119.699 138.975 1.00 73.14  ? 284 LYS B NZ    1 
ATOM   7773  N N     . VAL D 1 314 ? 117.460 116.453 145.374 1.00 71.58  ? 285 VAL B N     1 
ATOM   7774  C CA    . VAL D 1 314 ? 118.375 115.332 145.593 1.00 71.58  ? 285 VAL B CA    1 
ATOM   7775  C C     . VAL D 1 314 ? 117.636 114.155 146.225 1.00 71.58  ? 285 VAL B C     1 
ATOM   7776  O O     . VAL D 1 314 ? 117.780 113.006 145.791 1.00 71.58  ? 285 VAL B O     1 
ATOM   7777  C CB    . VAL D 1 314 ? 119.576 115.779 146.451 1.00 71.58  ? 285 VAL B CB    1 
ATOM   7778  C CG1   . VAL D 1 314 ? 120.452 114.567 146.865 1.00 71.58  ? 285 VAL B CG1   1 
ATOM   7779  C CG2   . VAL D 1 314 ? 120.392 116.869 145.712 1.00 71.58  ? 285 VAL B CG2   1 
ATOM   7780  N N     . VAL D 1 315 ? 116.822 114.423 147.251 1.00 69.43  ? 286 VAL B N     1 
ATOM   7781  C CA    . VAL D 1 315 ? 116.092 113.339 147.913 1.00 69.43  ? 286 VAL B CA    1 
ATOM   7782  C C     . VAL D 1 315 ? 115.020 112.769 146.988 1.00 69.43  ? 286 VAL B C     1 
ATOM   7783  O O     . VAL D 1 315 ? 114.730 111.567 147.043 1.00 69.43  ? 286 VAL B O     1 
ATOM   7784  C CB    . VAL D 1 315 ? 115.483 113.781 149.266 1.00 69.43  ? 286 VAL B CB    1 
ATOM   7785  C CG1   . VAL D 1 315 ? 114.917 112.562 150.030 1.00 69.43  ? 286 VAL B CG1   1 
ATOM   7786  C CG2   . VAL D 1 315 ? 116.525 114.507 150.172 1.00 69.43  ? 286 VAL B CG2   1 
ATOM   7787  N N     . ASN D 1 316 ? 114.394 113.606 146.155 1.00 73.85  ? 287 ASN B N     1 
ATOM   7788  C CA    . ASN D 1 316 ? 113.412 113.096 145.202 1.00 73.85  ? 287 ASN B CA    1 
ATOM   7789  C C     . ASN D 1 316 ? 114.069 112.163 144.193 1.00 73.85  ? 287 ASN B C     1 
ATOM   7790  O O     . ASN D 1 316 ? 113.531 111.091 143.885 1.00 73.85  ? 287 ASN B O     1 
ATOM   7791  C CB    . ASN D 1 316 ? 112.711 114.253 144.481 1.00 73.85  ? 287 ASN B CB    1 
ATOM   7792  C CG    . ASN D 1 316 ? 111.385 114.638 145.128 1.00 73.85  ? 287 ASN B CG    1 
ATOM   7793  O OD1   . ASN D 1 316 ? 110.550 113.782 145.426 1.00 73.85  ? 287 ASN B OD1   1 
ATOM   7794  N ND2   . ASN D 1 316 ? 111.186 115.934 145.345 1.00 73.85  ? 287 ASN B ND2   1 
ATOM   7795  N N     . ARG D 1 317 ? 115.244 112.545 143.685 1.00 78.80  ? 288 ARG B N     1 
ATOM   7796  C CA    . ARG D 1 317 ? 115.996 111.658 142.803 1.00 78.80  ? 288 ARG B CA    1 
ATOM   7797  C C     . ARG D 1 317 ? 116.404 110.380 143.525 1.00 78.80  ? 288 ARG B C     1 
ATOM   7798  O O     . ARG D 1 317 ? 116.408 109.296 142.930 1.00 78.80  ? 288 ARG B O     1 
ATOM   7799  C CB    . ARG D 1 317 ? 117.233 112.380 142.269 1.00 78.80  ? 288 ARG B CB    1 
ATOM   7800  C CG    . ARG D 1 317 ? 117.819 111.775 141.003 1.00 78.80  ? 288 ARG B CG    1 
ATOM   7801  C CD    . ARG D 1 317 ? 119.306 112.068 140.902 1.00 78.80  ? 288 ARG B CD    1 
ATOM   7802  N NE    . ARG D 1 317 ? 120.079 111.194 141.785 1.00 78.80  ? 288 ARG B NE    1 
ATOM   7803  C CZ    . ARG D 1 317 ? 121.255 111.477 142.337 1.00 78.80  ? 288 ARG B CZ    1 
ATOM   7804  N NH1   . ARG D 1 317 ? 121.899 112.611 142.091 1.00 78.80  ? 288 ARG B NH1   1 
ATOM   7805  N NH2   . ARG D 1 317 ? 121.811 110.590 143.157 1.00 78.80  ? 288 ARG B NH2   1 
ATOM   7806  N N     . TYR D 1 318 ? 116.747 110.487 144.810 1.00 77.70  ? 289 TYR B N     1 
ATOM   7807  C CA    . TYR D 1 318 ? 117.211 109.318 145.552 1.00 77.70  ? 289 TYR B CA    1 
ATOM   7808  C C     . TYR D 1 318 ? 116.077 108.321 145.770 1.00 77.70  ? 289 TYR B C     1 
ATOM   7809  O O     . TYR D 1 318 ? 116.251 107.114 145.567 1.00 77.70  ? 289 TYR B O     1 
ATOM   7810  C CB    . TYR D 1 318 ? 117.818 109.757 146.897 1.00 77.70  ? 289 TYR B CB    1 
ATOM   7811  C CG    . TYR D 1 318 ? 119.119 109.085 147.318 1.00 77.70  ? 289 TYR B CG    1 
ATOM   7812  C CD1   . TYR D 1 318 ? 119.348 107.731 147.106 1.00 77.70  ? 289 TYR B CD1   1 
ATOM   7813  C CD2   . TYR D 1 318 ? 120.126 109.826 147.924 1.00 77.70  ? 289 TYR B CD2   1 
ATOM   7814  C CE1   . TYR D 1 318 ? 120.533 107.137 147.489 1.00 77.70  ? 289 TYR B CE1   1 
ATOM   7815  C CE2   . TYR D 1 318 ? 121.314 109.238 148.310 1.00 77.70  ? 289 TYR B CE2   1 
ATOM   7816  C CZ    . TYR D 1 318 ? 121.512 107.894 148.089 1.00 77.70  ? 289 TYR B CZ    1 
ATOM   7817  O OH    . TYR D 1 318 ? 122.694 107.302 148.471 1.00 77.70  ? 289 TYR B OH    1 
ATOM   7818  N N     . ILE D 1 319 ? 114.904 108.811 146.181 1.00 77.23  ? 290 ILE B N     1 
ATOM   7819  C CA    . ILE D 1 319 ? 113.778 107.914 146.439 1.00 77.23  ? 290 ILE B CA    1 
ATOM   7820  C C     . ILE D 1 319 ? 113.199 107.371 145.138 1.00 77.23  ? 290 ILE B C     1 
ATOM   7821  O O     . ILE D 1 319 ? 112.737 106.224 145.096 1.00 77.23  ? 290 ILE B O     1 
ATOM   7822  C CB    . ILE D 1 319 ? 112.692 108.605 147.296 1.00 77.23  ? 290 ILE B CB    1 
ATOM   7823  C CG1   . ILE D 1 319 ? 111.635 107.588 147.749 1.00 77.23  ? 290 ILE B CG1   1 
ATOM   7824  C CG2   . ILE D 1 319 ? 112.008 109.753 146.548 1.00 77.23  ? 290 ILE B CG2   1 
ATOM   7825  C CD1   . ILE D 1 319 ? 110.756 108.085 148.870 1.00 77.23  ? 290 ILE B CD1   1 
ATOM   7826  N N     . ASP D 1 320 ? 113.194 108.167 144.060 1.00 84.94  ? 291 ASP B N     1 
ATOM   7827  C CA    . ASP D 1 320 ? 112.692 107.655 142.787 1.00 84.94  ? 291 ASP B CA    1 
ATOM   7828  C C     . ASP D 1 320 ? 113.570 106.546 142.217 1.00 84.94  ? 291 ASP B C     1 
ATOM   7829  O O     . ASP D 1 320 ? 113.080 105.728 141.433 1.00 84.94  ? 291 ASP B O     1 
ATOM   7830  C CB    . ASP D 1 320 ? 112.562 108.787 141.762 1.00 84.94  ? 291 ASP B CB    1 
ATOM   7831  C CG    . ASP D 1 320 ? 111.427 108.565 140.769 1.00 84.94  ? 291 ASP B CG    1 
ATOM   7832  O OD1   . ASP D 1 320 ? 110.962 107.415 140.610 1.00 84.94  ? 291 ASP B OD1   1 
ATOM   7833  O OD2   . ASP D 1 320 ? 110.995 109.555 140.143 1.00 84.94  ? 291 ASP B OD2   1 
ATOM   7834  N N     . GLU D 1 321 ? 114.850 106.498 142.593 1.00 86.80  ? 292 GLU B N     1 
ATOM   7835  C CA    . GLU D 1 321 ? 115.720 105.395 142.202 1.00 86.80  ? 292 GLU B CA    1 
ATOM   7836  C C     . GLU D 1 321 ? 115.407 104.090 142.930 1.00 86.80  ? 292 GLU B C     1 
ATOM   7837  O O     . GLU D 1 321 ? 115.967 103.053 142.557 1.00 86.80  ? 292 GLU B O     1 
ATOM   7838  C CB    . GLU D 1 321 ? 117.181 105.780 142.446 1.00 86.80  ? 292 GLU B CB    1 
ATOM   7839  C CG    . GLU D 1 321 ? 117.751 106.742 141.415 1.00 86.80  ? 292 GLU B CG    1 
ATOM   7840  C CD    . GLU D 1 321 ? 119.093 107.314 141.829 1.00 86.80  ? 292 GLU B CD    1 
ATOM   7841  O OE1   . GLU D 1 321 ? 119.963 106.536 142.272 1.00 86.80  ? 292 GLU B OE1   1 
ATOM   7842  O OE2   . GLU D 1 321 ? 119.278 108.543 141.713 1.00 86.80  ? 292 GLU B OE2   1 
ATOM   7843  N N     . GLY D 1 322 ? 114.547 104.103 143.947 1.00 88.89  ? 293 GLY B N     1 
ATOM   7844  C CA    . GLY D 1 322 ? 114.213 102.879 144.650 1.00 88.89  ? 293 GLY B CA    1 
ATOM   7845  C C     . GLY D 1 322 ? 115.318 102.358 145.539 1.00 88.89  ? 293 GLY B C     1 
ATOM   7846  O O     . GLY D 1 322 ? 115.484 101.138 145.653 1.00 88.89  ? 293 GLY B O     1 
ATOM   7847  N N     . VAL D 1 323 ? 116.077 103.258 146.163 1.00 85.58  ? 294 VAL B N     1 
ATOM   7848  C CA    . VAL D 1 323 ? 117.202 102.903 147.028 1.00 85.58  ? 294 VAL B CA    1 
ATOM   7849  C C     . VAL D 1 323 ? 117.139 103.569 148.398 1.00 85.58  ? 294 VAL B C     1 
ATOM   7850  O O     . VAL D 1 323 ? 117.714 103.029 149.362 1.00 85.58  ? 294 VAL B O     1 
ATOM   7851  C CB    . VAL D 1 323 ? 118.535 103.239 146.307 1.00 85.58  ? 294 VAL B CB    1 
ATOM   7852  C CG1   . VAL D 1 323 ? 118.543 104.675 145.778 1.00 85.58  ? 294 VAL B CG1   1 
ATOM   7853  C CG2   . VAL D 1 323 ? 119.760 102.960 147.182 1.00 85.58  ? 294 VAL B CG2   1 
ATOM   7854  N N     . ALA D 1 324 ? 116.449 104.703 148.543 1.00 78.24  ? 295 ALA B N     1 
ATOM   7855  C CA    . ALA D 1 324 ? 116.166 105.352 149.817 1.00 78.24  ? 295 ALA B CA    1 
ATOM   7856  C C     . ALA D 1 324 ? 114.668 105.288 150.087 1.00 78.24  ? 295 ALA B C     1 
ATOM   7857  O O     . ALA D 1 324 ? 113.860 105.325 149.155 1.00 78.24  ? 295 ALA B O     1 
ATOM   7858  C CB    . ALA D 1 324 ? 116.631 106.810 149.811 1.00 78.24  ? 295 ALA B CB    1 
ATOM   7859  N N     . GLU D 1 325 ? 114.307 105.192 151.370 1.00 69.16  ? 296 GLU B N     1 
ATOM   7860  C CA    . GLU D 1 325 ? 112.933 104.948 151.799 1.00 69.16  ? 296 GLU B CA    1 
ATOM   7861  C C     . GLU D 1 325 ? 112.575 105.989 152.851 1.00 69.16  ? 296 GLU B C     1 
ATOM   7862  O O     . GLU D 1 325 ? 113.316 106.181 153.822 1.00 69.16  ? 296 GLU B O     1 
ATOM   7863  C CB    . GLU D 1 325 ? 112.803 103.510 152.336 1.00 69.16  ? 296 GLU B CB    1 
ATOM   7864  C CG    . GLU D 1 325 ? 111.450 102.807 152.130 1.00 69.16  ? 296 GLU B CG    1 
ATOM   7865  C CD    . GLU D 1 325 ? 110.236 103.633 152.493 1.00 69.16  ? 296 GLU B CD    1 
ATOM   7866  O OE1   . GLU D 1 325 ? 109.223 103.547 151.769 1.00 69.16  ? 296 GLU B OE1   1 
ATOM   7867  O OE2   . GLU D 1 325 ? 110.252 104.288 153.550 1.00 69.16  ? 296 GLU B OE2   1 
ATOM   7868  N N     . LEU D 1 326 ? 111.434 106.651 152.657 1.00 59.47  ? 297 LEU B N     1 
ATOM   7869  C CA    . LEU D 1 326 ? 111.010 107.768 153.494 1.00 59.47  ? 297 LEU B CA    1 
ATOM   7870  C C     . LEU D 1 326 ? 110.151 107.286 154.654 1.00 59.47  ? 297 LEU B C     1 
ATOM   7871  O O     . LEU D 1 326 ? 109.166 106.569 154.446 1.00 59.47  ? 297 LEU B O     1 
ATOM   7872  C CB    . LEU D 1 326 ? 110.220 108.781 152.666 1.00 59.47  ? 297 LEU B CB    1 
ATOM   7873  C CG    . LEU D 1 326 ? 109.988 110.165 153.281 1.00 59.47  ? 297 LEU B CG    1 
ATOM   7874  C CD1   . LEU D 1 326 ? 111.246 111.014 153.250 1.00 59.47  ? 297 LEU B CD1   1 
ATOM   7875  C CD2   . LEU D 1 326 ? 108.841 110.862 152.565 1.00 59.47  ? 297 LEU B CD2   1 
ATOM   7876  N N     . VAL D 1 327 ? 110.509 107.712 155.863 1.00 51.45  ? 298 VAL B N     1 
ATOM   7877  C CA    . VAL D 1 327 ? 109.706 107.516 157.070 1.00 51.45  ? 298 VAL B CA    1 
ATOM   7878  C C     . VAL D 1 327 ? 109.324 108.918 157.547 1.00 51.45  ? 298 VAL B C     1 
ATOM   7879  O O     . VAL D 1 327 ? 110.136 109.583 158.210 1.00 51.45  ? 298 VAL B O     1 
ATOM   7880  C CB    . VAL D 1 327 ? 110.443 106.688 158.148 1.00 51.45  ? 298 VAL B CB    1 
ATOM   7881  C CG1   . VAL D 1 327 ? 110.445 105.200 157.765 1.00 51.45  ? 298 VAL B CG1   1 
ATOM   7882  C CG2   . VAL D 1 327 ? 111.892 107.171 158.459 1.00 51.45  ? 298 VAL B CG2   1 
ATOM   7883  N N     . PRO D 1 328 ? 108.149 109.451 157.185 1.00 46.58  ? 299 PRO B N     1 
ATOM   7884  C CA    . PRO D 1 328 ? 107.756 110.753 157.735 1.00 46.58  ? 299 PRO B CA    1 
ATOM   7885  C C     . PRO D 1 328 ? 107.445 110.650 159.216 1.00 46.58  ? 299 PRO B C     1 
ATOM   7886  O O     . PRO D 1 328 ? 106.901 109.647 159.684 1.00 46.58  ? 299 PRO B O     1 
ATOM   7887  C CB    . PRO D 1 328 ? 106.509 111.131 156.926 1.00 46.58  ? 299 PRO B CB    1 
ATOM   7888  C CG    . PRO D 1 328 ? 106.521 110.260 155.741 1.00 46.58  ? 299 PRO B CG    1 
ATOM   7889  C CD    . PRO D 1 328 ? 107.181 109.001 156.166 1.00 46.58  ? 299 PRO B CD    1 
ATOM   7890  N N     . GLY D 1 329 ? 107.794 111.711 159.947 1.00 39.76  ? 300 GLY B N     1 
ATOM   7891  C CA    . GLY D 1 329 ? 107.558 111.811 161.363 1.00 39.76  ? 300 GLY B CA    1 
ATOM   7892  C C     . GLY D 1 329 ? 106.431 112.761 161.698 1.00 39.76  ? 300 GLY B C     1 
ATOM   7893  O O     . GLY D 1 329 ? 105.584 113.092 160.857 1.00 39.76  ? 300 GLY B O     1 
ATOM   7894  N N     . VAL D 1 330 ? 106.432 113.218 162.948 1.00 37.37  ? 301 VAL B N     1 
ATOM   7895  C CA    . VAL D 1 330 ? 105.350 113.995 163.539 1.00 37.37  ? 301 VAL B CA    1 
ATOM   7896  C C     . VAL D 1 330 ? 105.951 115.281 164.087 1.00 37.37  ? 301 VAL B C     1 
ATOM   7897  O O     . VAL D 1 330 ? 106.793 115.236 164.990 1.00 37.37  ? 301 VAL B O     1 
ATOM   7898  C CB    . VAL D 1 330 ? 104.636 113.200 164.648 1.00 37.37  ? 301 VAL B CB    1 
ATOM   7899  C CG1   . VAL D 1 330 ? 103.735 114.090 165.495 1.00 37.37  ? 301 VAL B CG1   1 
ATOM   7900  C CG2   . VAL D 1 330 ? 103.825 112.049 164.049 1.00 37.37  ? 301 VAL B CG2   1 
ATOM   7901  N N     . LEU D 1 331 ? 105.519 116.418 163.543 1.00 40.82  ? 302 LEU B N     1 
ATOM   7902  C CA    . LEU D 1 331 ? 105.884 117.742 164.046 1.00 40.82  ? 302 LEU B CA    1 
ATOM   7903  C C     . LEU D 1 331 ? 104.761 118.195 164.969 1.00 40.82  ? 302 LEU B C     1 
ATOM   7904  O O     . LEU D 1 331 ? 103.756 118.744 164.513 1.00 40.82  ? 302 LEU B O     1 
ATOM   7905  C CB    . LEU D 1 331 ? 106.099 118.721 162.895 1.00 40.82  ? 302 LEU B CB    1 
ATOM   7906  C CG    . LEU D 1 331 ? 106.354 120.203 163.207 1.00 40.82  ? 302 LEU B CG    1 
ATOM   7907  C CD1   . LEU D 1 331 ? 107.713 120.380 163.841 1.00 40.82  ? 302 LEU B CD1   1 
ATOM   7908  C CD2   . LEU D 1 331 ? 106.246 121.028 161.939 1.00 40.82  ? 302 LEU B CD2   1 
ATOM   7909  N N     . PHE D 1 332 ? 104.938 117.980 166.268 1.00 35.60  ? 303 PHE B N     1 
ATOM   7910  C CA    . PHE D 1 332 ? 103.960 118.393 167.266 1.00 35.60  ? 303 PHE B CA    1 
ATOM   7911  C C     . PHE D 1 332 ? 104.230 119.842 167.652 1.00 35.60  ? 303 PHE B C     1 
ATOM   7912  O O     . PHE D 1 332 ? 105.310 120.156 168.164 1.00 35.60  ? 303 PHE B O     1 
ATOM   7913  C CB    . PHE D 1 332 ? 104.029 117.480 168.486 1.00 35.60  ? 303 PHE B CB    1 
ATOM   7914  C CG    . PHE D 1 332 ? 103.074 117.852 169.573 1.00 35.60  ? 303 PHE B CG    1 
ATOM   7915  C CD1   . PHE D 1 332 ? 101.745 117.503 169.486 1.00 35.60  ? 303 PHE B CD1   1 
ATOM   7916  C CD2   . PHE D 1 332 ? 103.505 118.545 170.685 1.00 35.60  ? 303 PHE B CD2   1 
ATOM   7917  C CE1   . PHE D 1 332 ? 100.864 117.834 170.485 1.00 35.60  ? 303 PHE B CE1   1 
ATOM   7918  C CE2   . PHE D 1 332 ? 102.625 118.883 171.685 1.00 35.60  ? 303 PHE B CE2   1 
ATOM   7919  C CZ    . PHE D 1 332 ? 101.302 118.528 171.584 1.00 35.60  ? 303 PHE B CZ    1 
ATOM   7920  N N     . ILE D 1 333 ? 103.251 120.713 167.412 1.00 37.60  ? 304 ILE B N     1 
ATOM   7921  C CA    . ILE D 1 333 ? 103.370 122.156 167.648 1.00 37.60  ? 304 ILE B CA    1 
ATOM   7922  C C     . ILE D 1 333 ? 102.356 122.493 168.736 1.00 37.60  ? 304 ILE B C     1 
ATOM   7923  O O     . ILE D 1 333 ? 101.185 122.766 168.461 1.00 37.60  ? 304 ILE B O     1 
ATOM   7924  C CB    . ILE D 1 333 ? 103.136 122.980 166.375 1.00 37.60  ? 304 ILE B CB    1 
ATOM   7925  C CG1   . ILE D 1 333 ? 103.947 122.402 165.204 1.00 37.60  ? 304 ILE B CG1   1 
ATOM   7926  C CG2   . ILE D 1 333 ? 103.522 124.466 166.585 1.00 37.60  ? 304 ILE B CG2   1 
ATOM   7927  C CD1   . ILE D 1 333 ? 103.983 123.271 163.955 1.00 37.60  ? 304 ILE B CD1   1 
ATOM   7928  N N     . ASP D 1 334 ? 102.805 122.487 169.987 1.00 39.62  ? 305 ASP B N     1 
ATOM   7929  C CA    . ASP D 1 334 ? 101.966 122.929 171.090 1.00 39.62  ? 305 ASP B CA    1 
ATOM   7930  C C     . ASP D 1 334 ? 101.859 124.450 171.094 1.00 39.62  ? 305 ASP B C     1 
ATOM   7931  O O     . ASP D 1 334 ? 102.708 125.155 170.542 1.00 39.62  ? 305 ASP B O     1 
ATOM   7932  C CB    . ASP D 1 334 ? 102.531 122.453 172.427 1.00 39.62  ? 305 ASP B CB    1 
ATOM   7933  C CG    . ASP D 1 334 ? 101.447 122.111 173.428 1.00 39.62  ? 305 ASP B CG    1 
ATOM   7934  O OD1   . ASP D 1 334 ? 100.461 122.871 173.521 1.00 39.62  ? 305 ASP B OD1   1 
ATOM   7935  O OD2   . ASP D 1 334 ? 101.581 121.083 174.123 1.00 39.62  ? 305 ASP B OD2   1 
ATOM   7936  N N     . GLU D 1 335 ? 100.812 124.948 171.754 1.00 43.91  ? 306 GLU B N     1 
ATOM   7937  C CA    . GLU D 1 335 ? 100.529 126.381 171.898 1.00 43.91  ? 306 GLU B CA    1 
ATOM   7938  C C     . GLU D 1 335 ? 100.473 127.053 170.521 1.00 43.91  ? 306 GLU B C     1 
ATOM   7939  O O     . GLU D 1 335 ? 101.276 127.921 170.172 1.00 43.91  ? 306 GLU B O     1 
ATOM   7940  C CB    . GLU D 1 335 ? 101.558 127.055 172.827 1.00 43.91  ? 306 GLU B CB    1 
ATOM   7941  C CG    . GLU D 1 335 ? 101.206 127.039 174.312 1.00 43.91  ? 306 GLU B CG    1 
ATOM   7942  C CD    . GLU D 1 335 ? 101.860 128.180 175.065 1.00 43.91  ? 306 GLU B CD    1 
ATOM   7943  O OE1   . GLU D 1 335 ? 103.107 128.249 175.073 1.00 43.91  ? 306 GLU B OE1   1 
ATOM   7944  O OE2   . GLU D 1 335 ? 101.130 129.010 175.645 1.00 43.91  ? 306 GLU B OE2   1 
ATOM   7945  N N     . VAL D 1 336 ? 99.521  126.585 169.713 1.00 44.60  ? 307 VAL B N     1 
ATOM   7946  C CA    . VAL D 1 336 ? 99.443  127.047 168.332 1.00 44.60  ? 307 VAL B CA    1 
ATOM   7947  C C     . VAL D 1 336 ? 99.042  128.518 168.269 1.00 44.60  ? 307 VAL B C     1 
ATOM   7948  O O     . VAL D 1 336 ? 99.442  129.233 167.345 1.00 44.60  ? 307 VAL B O     1 
ATOM   7949  C CB    . VAL D 1 336 ? 98.485  126.140 167.533 1.00 44.60  ? 307 VAL B CB    1 
ATOM   7950  C CG1   . VAL D 1 336 ? 97.020  126.463 167.833 1.00 44.60  ? 307 VAL B CG1   1 
ATOM   7951  C CG2   . VAL D 1 336 ? 98.780  126.224 166.040 1.00 44.60  ? 307 VAL B CG2   1 
ATOM   7952  N N     . HIS D 1 337 ? 98.271  129.001 169.250 1.00 48.20  ? 308 HIS B N     1 
ATOM   7953  C CA    . HIS D 1 337 ? 97.869  130.405 169.273 1.00 48.20  ? 308 HIS B CA    1 
ATOM   7954  C C     . HIS D 1 337 ? 99.048  131.359 169.427 1.00 48.20  ? 308 HIS B C     1 
ATOM   7955  O O     . HIS D 1 337 ? 98.929  132.531 169.058 1.00 48.20  ? 308 HIS B O     1 
ATOM   7956  C CB    . HIS D 1 337 ? 96.871  130.657 170.408 1.00 48.20  ? 308 HIS B CB    1 
ATOM   7957  C CG    . HIS D 1 337 ? 97.422  130.388 171.774 1.00 48.20  ? 308 HIS B CG    1 
ATOM   7958  N ND1   . HIS D 1 337 ? 97.518  129.118 172.302 1.00 48.20  ? 308 HIS B ND1   1 
ATOM   7959  C CD2   . HIS D 1 337 ? 97.898  131.227 172.724 1.00 48.20  ? 308 HIS B CD2   1 
ATOM   7960  C CE1   . HIS D 1 337 ? 98.035  129.186 173.516 1.00 48.20  ? 308 HIS B CE1   1 
ATOM   7961  N NE2   . HIS D 1 337 ? 98.274  130.455 173.796 1.00 48.20  ? 308 HIS B NE2   1 
ATOM   7962  N N     . MET D 1 338 ? 100.179 130.893 169.963 1.00 52.36  ? 309 MET B N     1 
ATOM   7963  C CA    . MET D 1 338 ? 101.348 131.752 170.104 1.00 52.36  ? 309 MET B CA    1 
ATOM   7964  C C     . MET D 1 338 ? 101.935 132.167 168.759 1.00 52.36  ? 309 MET B C     1 
ATOM   7965  O O     . MET D 1 338 ? 102.619 133.192 168.691 1.00 52.36  ? 309 MET B O     1 
ATOM   7966  C CB    . MET D 1 338 ? 102.415 131.039 170.937 1.00 52.36  ? 309 MET B CB    1 
ATOM   7967  C CG    . MET D 1 338 ? 103.434 131.961 171.584 1.00 52.36  ? 309 MET B CG    1 
ATOM   7968  S SD    . MET D 1 338 ? 102.857 132.603 173.164 1.00 52.36  ? 309 MET B SD    1 
ATOM   7969  C CE    . MET D 1 338 ? 103.743 134.155 173.240 1.00 52.36  ? 309 MET B CE    1 
ATOM   7970  N N     . LEU D 1 339 ? 101.696 131.401 167.696 1.00 50.44  ? 310 LEU B N     1 
ATOM   7971  C CA    . LEU D 1 339 ? 102.158 131.788 166.373 1.00 50.44  ? 310 LEU B CA    1 
ATOM   7972  C C     . LEU D 1 339 ? 101.316 132.947 165.839 1.00 50.44  ? 310 LEU B C     1 
ATOM   7973  O O     . LEU D 1 339 ? 100.283 133.314 166.406 1.00 50.44  ? 310 LEU B O     1 
ATOM   7974  C CB    . LEU D 1 339 ? 102.098 130.597 165.416 1.00 50.44  ? 310 LEU B CB    1 
ATOM   7975  C CG    . LEU D 1 339 ? 102.802 129.304 165.840 1.00 50.44  ? 310 LEU B CG    1 
ATOM   7976  C CD1   . LEU D 1 339 ? 102.693 128.265 164.737 1.00 50.44  ? 310 LEU B CD1   1 
ATOM   7977  C CD2   . LEU D 1 339 ? 104.259 129.536 166.200 1.00 50.44  ? 310 LEU B CD2   1 
ATOM   7978  N N     . ASP D 1 340 ? 101.776 133.520 164.728 1.00 57.78  ? 311 ASP B N     1 
ATOM   7979  C CA    . ASP D 1 340 ? 101.204 134.712 164.103 1.00 57.78  ? 311 ASP B CA    1 
ATOM   7980  C C     . ASP D 1 340 ? 100.842 134.400 162.648 1.00 57.78  ? 311 ASP B C     1 
ATOM   7981  O O     . ASP D 1 340 ? 100.979 133.265 162.186 1.00 57.78  ? 311 ASP B O     1 
ATOM   7982  C CB    . ASP D 1 340 ? 102.178 135.894 164.233 1.00 57.78  ? 311 ASP B CB    1 
ATOM   7983  C CG    . ASP D 1 340 ? 103.581 135.562 163.763 1.00 57.78  ? 311 ASP B CG    1 
ATOM   7984  O OD1   . ASP D 1 340 ? 103.780 134.484 163.171 1.00 57.78  ? 311 ASP B OD1   1 
ATOM   7985  O OD2   . ASP D 1 340 ? 104.492 136.385 163.989 1.00 57.78  ? 311 ASP B OD2   1 
ATOM   7986  N N     . MET D 1 341 ? 100.369 135.429 161.933 1.00 57.45  ? 312 MET B N     1 
ATOM   7987  C CA    . MET D 1 341 ? 99.873  135.245 160.566 1.00 57.45  ? 312 MET B CA    1 
ATOM   7988  C C     . MET D 1 341 ? 100.974 134.766 159.628 1.00 57.45  ? 312 MET B C     1 
ATOM   7989  O O     . MET D 1 341 ? 100.724 133.940 158.740 1.00 57.45  ? 312 MET B O     1 
ATOM   7990  C CB    . MET D 1 341 ? 99.275  136.553 160.025 1.00 57.45  ? 312 MET B CB    1 
ATOM   7991  C CG    . MET D 1 341 ? 97.921  136.457 159.311 1.00 57.45  ? 312 MET B CG    1 
ATOM   7992  S SD    . MET D 1 341 ? 96.556  135.667 160.189 1.00 57.45  ? 312 MET B SD    1 
ATOM   7993  C CE    . MET D 1 341 ? 95.341  135.576 158.876 1.00 57.45  ? 312 MET B CE    1 
ATOM   7994  N N     . GLU D 1 342 ? 102.193 135.286 159.798 1.00 58.31  ? 313 GLU B N     1 
ATOM   7995  C CA    . GLU D 1 342 ? 103.307 134.885 158.943 1.00 58.31  ? 313 GLU B CA    1 
ATOM   7996  C C     . GLU D 1 342 ? 103.617 133.402 159.115 1.00 58.31  ? 313 GLU B C     1 
ATOM   7997  O O     . GLU D 1 342 ? 103.773 132.671 158.130 1.00 58.31  ? 313 GLU B O     1 
ATOM   7998  C CB    . GLU D 1 342 ? 104.532 135.755 159.259 1.00 58.31  ? 313 GLU B CB    1 
ATOM   7999  C CG    . GLU D 1 342 ? 105.911 135.230 158.816 1.00 58.31  ? 313 GLU B CG    1 
ATOM   8000  C CD    . GLU D 1 342 ? 105.972 134.856 157.345 1.00 58.31  ? 313 GLU B CD    1 
ATOM   8001  O OE1   . GLU D 1 342 ? 105.159 135.384 156.558 1.00 58.31  ? 313 GLU B OE1   1 
ATOM   8002  O OE2   . GLU D 1 342 ? 106.835 134.031 156.980 1.00 58.31  ? 313 GLU B OE2   1 
ATOM   8003  N N     . CYS D 1 343 ? 103.692 132.940 160.366 1.00 55.59  ? 314 CYS B N     1 
ATOM   8004  C CA    . CYS D 1 343 ? 103.998 131.537 160.628 1.00 55.59  ? 314 CYS B CA    1 
ATOM   8005  C C     . CYS D 1 343 ? 102.903 130.615 160.109 1.00 55.59  ? 314 CYS B C     1 
ATOM   8006  O O     . CYS D 1 343 ? 103.193 129.568 159.520 1.00 55.59  ? 314 CYS B O     1 
ATOM   8007  C CB    . CYS D 1 343 ? 104.212 131.327 162.126 1.00 55.59  ? 314 CYS B CB    1 
ATOM   8008  S SG    . CYS D 1 343 ? 105.713 132.099 162.778 1.00 55.59  ? 314 CYS B SG    1 
ATOM   8009  N N     . PHE D 1 344 ? 101.637 130.987 160.313 1.00 50.76  ? 315 PHE B N     1 
ATOM   8010  C CA    . PHE D 1 344 ? 100.541 130.143 159.849 1.00 50.76  ? 315 PHE B CA    1 
ATOM   8011  C C     . PHE D 1 344 ? 100.484 130.089 158.328 1.00 50.76  ? 315 PHE B C     1 
ATOM   8012  O O     . PHE D 1 344 ? 100.266 129.017 157.750 1.00 50.76  ? 315 PHE B O     1 
ATOM   8013  C CB    . PHE D 1 344 ? 99.209  130.650 160.407 1.00 50.76  ? 315 PHE B CB    1 
ATOM   8014  C CG    . PHE D 1 344 ? 98.937  130.248 161.835 1.00 50.76  ? 315 PHE B CG    1 
ATOM   8015  C CD1   . PHE D 1 344 ? 98.781  128.919 162.189 1.00 50.76  ? 315 PHE B CD1   1 
ATOM   8016  C CD2   . PHE D 1 344 ? 98.800  131.211 162.818 1.00 50.76  ? 315 PHE B CD2   1 
ATOM   8017  C CE1   . PHE D 1 344 ? 98.521  128.561 163.488 1.00 50.76  ? 315 PHE B CE1   1 
ATOM   8018  C CE2   . PHE D 1 344 ? 98.535  130.855 164.122 1.00 50.76  ? 315 PHE B CE2   1 
ATOM   8019  C CZ    . PHE D 1 344 ? 98.396  129.528 164.455 1.00 50.76  ? 315 PHE B CZ    1 
ATOM   8020  N N     . SER D 1 345 ? 100.673 131.231 157.662 1.00 54.89  ? 316 SER B N     1 
ATOM   8021  C CA    . SER D 1 345 ? 100.684 131.240 156.202 1.00 54.89  ? 316 SER B CA    1 
ATOM   8022  C C     . SER D 1 345 ? 101.853 130.431 155.659 1.00 54.89  ? 316 SER B C     1 
ATOM   8023  O O     . SER D 1 345 ? 101.712 129.706 154.664 1.00 54.89  ? 316 SER B O     1 
ATOM   8024  C CB    . SER D 1 345 ? 100.746 132.679 155.692 1.00 54.89  ? 316 SER B CB    1 
ATOM   8025  O OG    . SER D 1 345 ? 101.517 133.489 156.562 1.00 54.89  ? 316 SER B OG    1 
ATOM   8026  N N     . TYR D 1 346 ? 103.014 130.528 156.308 1.00 51.98  ? 317 TYR B N     1 
ATOM   8027  C CA    . TYR D 1 346 ? 104.165 129.752 155.871 1.00 51.98  ? 317 TYR B CA    1 
ATOM   8028  C C     . TYR D 1 346 ? 103.939 128.259 156.069 1.00 51.98  ? 317 TYR B C     1 
ATOM   8029  O O     . TYR D 1 346 ? 104.366 127.451 155.240 1.00 51.98  ? 317 TYR B O     1 
ATOM   8030  C CB    . TYR D 1 346 ? 105.414 130.209 156.615 1.00 51.98  ? 317 TYR B CB    1 
ATOM   8031  C CG    . TYR D 1 346 ? 106.675 129.637 156.034 1.00 51.98  ? 317 TYR B CG    1 
ATOM   8032  C CD1   . TYR D 1 346 ? 107.293 130.232 154.944 1.00 51.98  ? 317 TYR B CD1   1 
ATOM   8033  C CD2   . TYR D 1 346 ? 107.244 128.497 156.568 1.00 51.98  ? 317 TYR B CD2   1 
ATOM   8034  C CE1   . TYR D 1 346 ? 108.447 129.704 154.407 1.00 51.98  ? 317 TYR B CE1   1 
ATOM   8035  C CE2   . TYR D 1 346 ? 108.383 127.963 156.042 1.00 51.98  ? 317 TYR B CE2   1 
ATOM   8036  C CZ    . TYR D 1 346 ? 108.990 128.567 154.962 1.00 51.98  ? 317 TYR B CZ    1 
ATOM   8037  O OH    . TYR D 1 346 ? 110.143 128.035 154.433 1.00 51.98  ? 317 TYR B OH    1 
ATOM   8038  N N     . LEU D 1 347 ? 103.292 127.868 157.169 1.00 48.99  ? 318 LEU B N     1 
ATOM   8039  C CA    . LEU D 1 347 ? 102.983 126.453 157.365 1.00 48.99  ? 318 LEU B CA    1 
ATOM   8040  C C     . LEU D 1 347 ? 101.967 125.966 156.340 1.00 48.99  ? 318 LEU B C     1 
ATOM   8041  O O     . LEU D 1 347 ? 102.058 124.828 155.864 1.00 48.99  ? 318 LEU B O     1 
ATOM   8042  C CB    . LEU D 1 347 ? 102.466 126.206 158.782 1.00 48.99  ? 318 LEU B CB    1 
ATOM   8043  C CG    . LEU D 1 347 ? 103.518 125.995 159.876 1.00 48.99  ? 318 LEU B CG    1 
ATOM   8044  C CD1   . LEU D 1 347 ? 102.873 126.113 161.247 1.00 48.99  ? 318 LEU B CD1   1 
ATOM   8045  C CD2   . LEU D 1 347 ? 104.219 124.646 159.732 1.00 48.99  ? 318 LEU B CD2   1 
ATOM   8046  N N     . ASN D 1 348 ? 100.991 126.812 155.996 1.00 48.40  ? 319 ASN B N     1 
ATOM   8047  C CA    . ASN D 1 348 ? 100.034 126.463 154.950 1.00 48.40  ? 319 ASN B CA    1 
ATOM   8048  C C     . ASN D 1 348 ? 100.737 126.254 153.617 1.00 48.40  ? 319 ASN B C     1 
ATOM   8049  O O     . ASN D 1 348 ? 100.387 125.346 152.856 1.00 48.40  ? 319 ASN B O     1 
ATOM   8050  C CB    . ASN D 1 348 ? 98.975  127.557 154.827 1.00 48.40  ? 319 ASN B CB    1 
ATOM   8051  C CG    . ASN D 1 348 ? 97.790  127.135 153.979 1.00 48.40  ? 319 ASN B CG    1 
ATOM   8052  O OD1   . ASN D 1 348 ? 97.717  126.000 153.508 1.00 48.40  ? 319 ASN B OD1   1 
ATOM   8053  N ND2   . ASN D 1 348 ? 96.856  128.057 153.773 1.00 48.40  ? 319 ASN B ND2   1 
ATOM   8054  N N     . ARG D 1 349 ? 101.730 127.091 153.317 1.00 55.71  ? 320 ARG B N     1 
ATOM   8055  C CA    . ARG D 1 349 ? 102.537 126.884 152.118 1.00 55.71  ? 320 ARG B CA    1 
ATOM   8056  C C     . ARG D 1 349 ? 103.336 125.586 152.197 1.00 55.71  ? 320 ARG B C     1 
ATOM   8057  O O     . ARG D 1 349 ? 103.327 124.783 151.257 1.00 55.71  ? 320 ARG B O     1 
ATOM   8058  C CB    . ARG D 1 349 ? 103.472 128.074 151.908 1.00 55.71  ? 320 ARG B CB    1 
ATOM   8059  C CG    . ARG D 1 349 ? 104.295 127.987 150.628 1.00 55.71  ? 320 ARG B CG    1 
ATOM   8060  C CD    . ARG D 1 349 ? 104.669 129.341 150.032 1.00 55.71  ? 320 ARG B CD    1 
ATOM   8061  N NE    . ARG D 1 349 ? 105.054 130.335 151.035 1.00 55.71  ? 320 ARG B NE    1 
ATOM   8062  C CZ    . ARG D 1 349 ? 105.907 131.338 150.851 1.00 55.71  ? 320 ARG B CZ    1 
ATOM   8063  N NH1   . ARG D 1 349 ? 106.456 131.596 149.669 1.00 55.71  ? 320 ARG B NH1   1 
ATOM   8064  N NH2   . ARG D 1 349 ? 106.211 132.121 151.882 1.00 55.71  ? 320 ARG B NH2   1 
ATOM   8065  N N     . ALA D 1 350 ? 104.030 125.361 153.314 1.00 49.70  ? 321 ALA B N     1 
ATOM   8066  C CA    . ALA D 1 350 ? 104.977 124.255 153.405 1.00 49.70  ? 321 ALA B CA    1 
ATOM   8067  C C     . ALA D 1 350 ? 104.303 122.897 153.543 1.00 49.70  ? 321 ALA B C     1 
ATOM   8068  O O     . ALA D 1 350 ? 104.949 121.877 153.278 1.00 49.70  ? 321 ALA B O     1 
ATOM   8069  C CB    . ALA D 1 350 ? 105.922 124.476 154.585 1.00 49.70  ? 321 ALA B CB    1 
ATOM   8070  N N     . LEU D 1 351 ? 103.035 122.849 153.963 1.00 47.85  ? 322 LEU B N     1 
ATOM   8071  C CA    . LEU D 1 351 ? 102.355 121.562 154.081 1.00 47.85  ? 322 LEU B CA    1 
ATOM   8072  C C     . LEU D 1 351 ? 102.147 120.894 152.725 1.00 47.85  ? 322 LEU B C     1 
ATOM   8073  O O     . LEU D 1 351 ? 102.056 119.663 152.656 1.00 47.85  ? 322 LEU B O     1 
ATOM   8074  C CB    . LEU D 1 351 ? 101.012 121.741 154.789 1.00 47.85  ? 322 LEU B CB    1 
ATOM   8075  C CG    . LEU D 1 351 ? 101.070 121.833 156.317 1.00 47.85  ? 322 LEU B CG    1 
ATOM   8076  C CD1   . LEU D 1 351 ? 99.813  122.494 156.856 1.00 47.85  ? 322 LEU B CD1   1 
ATOM   8077  C CD2   . LEU D 1 351 ? 101.262 120.460 156.946 1.00 47.85  ? 322 LEU B CD2   1 
ATOM   8078  N N     . GLU D 1 352 ? 102.078 121.672 151.642 1.00 52.09  ? 323 GLU B N     1 
ATOM   8079  C CA    . GLU D 1 352 ? 101.850 121.105 150.316 1.00 52.09  ? 323 GLU B CA    1 
ATOM   8080  C C     . GLU D 1 352 ? 103.080 120.423 149.729 1.00 52.09  ? 323 GLU B C     1 
ATOM   8081  O O     . GLU D 1 352 ? 102.959 119.785 148.678 1.00 52.09  ? 323 GLU B O     1 
ATOM   8082  C CB    . GLU D 1 352 ? 101.370 122.185 149.330 1.00 52.09  ? 323 GLU B CB    1 
ATOM   8083  C CG    . GLU D 1 352 ? 100.415 123.300 149.843 1.00 52.09  ? 323 GLU B CG    1 
ATOM   8084  C CD    . GLU D 1 352 ? 99.286  122.860 150.785 1.00 52.09  ? 323 GLU B CD    1 
ATOM   8085  O OE1   . GLU D 1 352 ? 99.023  121.653 150.963 1.00 52.09  ? 323 GLU B OE1   1 
ATOM   8086  O OE2   . GLU D 1 352 ? 98.648  123.761 151.365 1.00 52.09  ? 323 GLU B OE2   1 
ATOM   8087  N N     . SER D 1 353 ? 104.252 120.546 150.354 1.00 54.56  ? 324 SER B N     1 
ATOM   8088  C CA    . SER D 1 353 ? 105.429 119.843 149.864 1.00 54.56  ? 324 SER B CA    1 
ATOM   8089  C C     . SER D 1 353 ? 105.236 118.337 149.994 1.00 54.56  ? 324 SER B C     1 
ATOM   8090  O O     . SER D 1 353 ? 104.564 117.850 150.907 1.00 54.56  ? 324 SER B O     1 
ATOM   8091  C CB    . SER D 1 353 ? 106.674 120.287 150.632 1.00 54.56  ? 324 SER B CB    1 
ATOM   8092  O OG    . SER D 1 353 ? 106.580 119.942 152.001 1.00 54.56  ? 324 SER B OG    1 
ATOM   8093  N N     . SER D 1 354 ? 105.824 117.599 149.049 1.00 60.10  ? 325 SER B N     1 
ATOM   8094  C CA    . SER D 1 354 ? 105.601 116.158 148.977 1.00 60.10  ? 325 SER B CA    1 
ATOM   8095  C C     . SER D 1 354 ? 106.178 115.434 150.187 1.00 60.10  ? 325 SER B C     1 
ATOM   8096  O O     . SER D 1 354 ? 105.556 114.503 150.710 1.00 60.10  ? 325 SER B O     1 
ATOM   8097  C CB    . SER D 1 354 ? 106.205 115.604 147.688 1.00 60.10  ? 325 SER B CB    1 
ATOM   8098  O OG    . SER D 1 354 ? 105.722 116.307 146.557 1.00 60.10  ? 325 SER B OG    1 
ATOM   8099  N N     . LEU D 1 355 ? 107.356 115.852 150.652 1.00 58.38  ? 326 LEU B N     1 
ATOM   8100  C CA    . LEU D 1 355 ? 108.069 115.178 151.728 1.00 58.38  ? 326 LEU B CA    1 
ATOM   8101  C C     . LEU D 1 355 ? 107.705 115.718 153.113 1.00 58.38  ? 326 LEU B C     1 
ATOM   8102  O O     . LEU D 1 355 ? 108.478 115.535 154.059 1.00 58.38  ? 326 LEU B O     1 
ATOM   8103  C CB    . LEU D 1 355 ? 109.582 115.298 151.500 1.00 58.38  ? 326 LEU B CB    1 
ATOM   8104  C CG    . LEU D 1 355 ? 110.172 114.700 150.216 1.00 58.38  ? 326 LEU B CG    1 
ATOM   8105  C CD1   . LEU D 1 355 ? 111.668 114.980 150.130 1.00 58.38  ? 326 LEU B CD1   1 
ATOM   8106  C CD2   . LEU D 1 355 ? 109.927 113.202 150.124 1.00 58.38  ? 326 LEU B CD2   1 
ATOM   8107  N N     . SER D 1 356 ? 106.549 116.361 153.262 1.00 49.88  ? 327 SER B N     1 
ATOM   8108  C CA    . SER D 1 356 ? 106.220 116.991 154.529 1.00 49.88  ? 327 SER B CA    1 
ATOM   8109  C C     . SER D 1 356 ? 105.909 115.935 155.593 1.00 49.88  ? 327 SER B C     1 
ATOM   8110  O O     . SER D 1 356 ? 105.509 114.816 155.263 1.00 49.88  ? 327 SER B O     1 
ATOM   8111  C CB    . SER D 1 356 ? 105.025 117.926 154.369 1.00 49.88  ? 327 SER B CB    1 
ATOM   8112  O OG    . SER D 1 356 ? 103.907 117.243 153.830 1.00 49.88  ? 327 SER B OG    1 
ATOM   8113  N N     . PRO D 1 357 ? 106.089 116.269 156.900 1.00 44.34  ? 328 PRO B N     1 
ATOM   8114  C CA    . PRO D 1 357 ? 105.705 115.333 157.960 1.00 44.34  ? 328 PRO B CA    1 
ATOM   8115  C C     . PRO D 1 357 ? 104.261 115.555 158.375 1.00 44.34  ? 328 PRO B C     1 
ATOM   8116  O O     . PRO D 1 357 ? 103.571 116.395 157.790 1.00 44.34  ? 328 PRO B O     1 
ATOM   8117  C CB    . PRO D 1 357 ? 106.688 115.681 159.079 1.00 44.34  ? 328 PRO B CB    1 
ATOM   8118  C CG    . PRO D 1 357 ? 106.819 117.157 158.955 1.00 44.34  ? 328 PRO B CG    1 
ATOM   8119  C CD    . PRO D 1 357 ? 106.587 117.518 157.502 1.00 44.34  ? 328 PRO B CD    1 
ATOM   8120  N N     . ILE D 1 358 ? 103.798 114.817 159.382 1.00 40.72  ? 329 ILE B N     1 
ATOM   8121  C CA    . ILE D 1 358 ? 102.421 114.922 159.873 1.00 40.72  ? 329 ILE B CA    1 
ATOM   8122  C C     . ILE D 1 358 ? 102.443 115.994 160.957 1.00 40.72  ? 329 ILE B C     1 
ATOM   8123  O O     . ILE D 1 358 ? 102.731 115.727 162.122 1.00 40.72  ? 329 ILE B O     1 
ATOM   8124  C CB    . ILE D 1 358 ? 101.899 113.582 160.386 1.00 40.72  ? 329 ILE B CB    1 
ATOM   8125  C CG1   . ILE D 1 358 ? 101.924 112.544 159.251 1.00 40.72  ? 329 ILE B CG1   1 
ATOM   8126  C CG2   . ILE D 1 358 ? 100.488 113.737 160.996 1.00 40.72  ? 329 ILE B CG2   1 
ATOM   8127  C CD1   . ILE D 1 358 ? 102.814 111.379 159.551 1.00 40.72  ? 329 ILE B CD1   1 
ATOM   8128  N N     . VAL D 1 359 ? 102.122 117.225 160.569 1.00 44.40  ? 330 VAL B N     1 
ATOM   8129  C CA    . VAL D 1 359 ? 102.104 118.325 161.526 1.00 44.40  ? 330 VAL B CA    1 
ATOM   8130  C C     . VAL D 1 359 ? 100.869 118.167 162.403 1.00 44.40  ? 330 VAL B C     1 
ATOM   8131  O O     . VAL D 1 359 ? 99.741  118.124 161.897 1.00 44.40  ? 330 VAL B O     1 
ATOM   8132  C CB    . VAL D 1 359 ? 102.119 119.681 160.804 1.00 44.40  ? 330 VAL B CB    1 
ATOM   8133  C CG1   . VAL D 1 359 ? 102.242 120.844 161.800 1.00 44.40  ? 330 VAL B CG1   1 
ATOM   8134  C CG2   . VAL D 1 359 ? 103.255 119.720 159.784 1.00 44.40  ? 330 VAL B CG2   1 
ATOM   8135  N N     . ILE D 1 360 ? 101.080 118.086 163.716 1.00 50.54  ? 331 ILE B N     1 
ATOM   8136  C CA    . ILE D 1 360 ? 100.012 117.891 164.702 1.00 50.54  ? 331 ILE B CA    1 
ATOM   8137  C C     . ILE D 1 360 ? 99.994  119.143 165.570 1.00 50.54  ? 331 ILE B C     1 
ATOM   8138  O O     . ILE D 1 360 ? 100.725 119.248 166.557 1.00 50.54  ? 331 ILE B O     1 
ATOM   8139  C CB    . ILE D 1 360 ? 100.209 116.627 165.547 1.00 50.54  ? 331 ILE B CB    1 
ATOM   8140  C CG1   . ILE D 1 360 ? 100.166 115.378 164.644 1.00 50.54  ? 331 ILE B CG1   1 
ATOM   8141  C CG2   . ILE D 1 360 ? 99.161  116.606 166.702 1.00 50.54  ? 331 ILE B CG2   1 
ATOM   8142  C CD1   . ILE D 1 360 ? 100.394 114.047 165.336 1.00 50.54  ? 331 ILE B CD1   1 
ATOM   8143  N N     . PHE D 1 361 ? 99.146  120.102 165.217 1.00 40.30  ? 332 PHE B N     1 
ATOM   8144  C CA    . PHE D 1 361 ? 98.889  121.219 166.109 1.00 40.30  ? 332 PHE B CA    1 
ATOM   8145  C C     . PHE D 1 361 ? 98.197  120.714 167.367 1.00 40.30  ? 332 PHE B C     1 
ATOM   8146  O O     . PHE D 1 361 ? 97.497  119.698 167.349 1.00 40.30  ? 332 PHE B O     1 
ATOM   8147  C CB    . PHE D 1 361 ? 97.991  122.267 165.438 1.00 40.30  ? 332 PHE B CB    1 
ATOM   8148  C CG    . PHE D 1 361 ? 98.587  122.962 164.221 1.00 40.30  ? 332 PHE B CG    1 
ATOM   8149  C CD1   . PHE D 1 361 ? 99.934  122.890 163.886 1.00 40.30  ? 332 PHE B CD1   1 
ATOM   8150  C CD2   . PHE D 1 361 ? 97.754  123.703 163.404 1.00 40.30  ? 332 PHE B CD2   1 
ATOM   8151  C CE1   . PHE D 1 361 ? 100.419 123.543 162.774 1.00 40.30  ? 332 PHE B CE1   1 
ATOM   8152  C CE2   . PHE D 1 361 ? 98.239  124.351 162.293 1.00 40.30  ? 332 PHE B CE2   1 
ATOM   8153  C CZ    . PHE D 1 361 ? 99.572  124.270 161.979 1.00 40.30  ? 332 PHE B CZ    1 
ATOM   8154  N N     . ALA D 1 362 ? 98.400  121.434 168.468 1.00 39.94  ? 333 ALA B N     1 
ATOM   8155  C CA    . ALA D 1 362 ? 97.704  121.170 169.719 1.00 39.94  ? 333 ALA B CA    1 
ATOM   8156  C C     . ALA D 1 362 ? 97.335  122.494 170.359 1.00 39.94  ? 333 ALA B C     1 
ATOM   8157  O O     . ALA D 1 362 ? 98.126  123.440 170.331 1.00 39.94  ? 333 ALA B O     1 
ATOM   8158  C CB    . ALA D 1 362 ? 98.554  120.338 170.678 1.00 39.94  ? 333 ALA B CB    1 
ATOM   8159  N N     . THR D 1 363 ? 96.131  122.558 170.926 1.00 42.52  ? 334 THR B N     1 
ATOM   8160  C CA    . THR D 1 363 ? 95.619  123.816 171.451 1.00 42.52  ? 334 THR B CA    1 
ATOM   8161  C C     . THR D 1 363 ? 94.626  123.567 172.574 1.00 42.52  ? 334 THR B C     1 
ATOM   8162  O O     . THR D 1 363 ? 93.982  122.512 172.645 1.00 42.52  ? 334 THR B O     1 
ATOM   8163  C CB    . THR D 1 363 ? 94.956  124.656 170.352 1.00 42.52  ? 334 THR B CB    1 
ATOM   8164  O OG1   . THR D 1 363 ? 94.691  125.972 170.851 1.00 42.52  ? 334 THR B OG1   1 
ATOM   8165  C CG2   . THR D 1 363 ? 93.651  124.025 169.883 1.00 42.52  ? 334 THR B CG2   1 
ATOM   8166  N N     . ASN D 1 364 ? 94.518  124.576 173.452 1.00 39.64  ? 335 ASN B N     1 
ATOM   8167  C CA    . ASN D 1 364 ? 93.560  124.594 174.550 1.00 39.64  ? 335 ASN B CA    1 
ATOM   8168  C C     . ASN D 1 364 ? 92.856  125.944 174.681 1.00 39.64  ? 335 ASN B C     1 
ATOM   8169  O O     . ASN D 1 364 ? 92.333  126.248 175.760 1.00 39.64  ? 335 ASN B O     1 
ATOM   8170  C CB    . ASN D 1 364 ? 94.258  124.242 175.870 1.00 39.64  ? 335 ASN B CB    1 
ATOM   8171  C CG    . ASN D 1 364 ? 95.351  125.226 176.235 1.00 39.64  ? 335 ASN B CG    1 
ATOM   8172  O OD1   . ASN D 1 364 ? 96.511  125.044 175.868 1.00 39.64  ? 335 ASN B OD1   1 
ATOM   8173  N ND2   . ASN D 1 364 ? 94.992  126.264 176.980 1.00 39.64  ? 335 ASN B ND2   1 
ATOM   8174  N N     . ARG D 1 365 ? 92.825  126.751 173.617 1.00 46.10  ? 336 ARG B N     1 
ATOM   8175  C CA    . ARG D 1 365 ? 92.194  128.067 173.601 1.00 46.10  ? 336 ARG B CA    1 
ATOM   8176  C C     . ARG D 1 365 ? 90.996  128.013 172.665 1.00 46.10  ? 336 ARG B C     1 
ATOM   8177  O O     . ARG D 1 365 ? 91.121  127.568 171.522 1.00 46.10  ? 336 ARG B O     1 
ATOM   8178  C CB    . ARG D 1 365 ? 93.175  129.146 173.136 1.00 46.10  ? 336 ARG B CB    1 
ATOM   8179  C CG    . ARG D 1 365 ? 94.422  129.316 174.009 1.00 46.10  ? 336 ARG B CG    1 
ATOM   8180  C CD    . ARG D 1 365 ? 94.187  130.270 175.168 1.00 46.10  ? 336 ARG B CD    1 
ATOM   8181  N NE    . ARG D 1 365 ? 94.576  131.638 174.839 1.00 46.10  ? 336 ARG B NE    1 
ATOM   8182  C CZ    . ARG D 1 365 ? 94.208  132.729 175.503 1.00 46.10  ? 336 ARG B CZ    1 
ATOM   8183  N NH1   . ARG D 1 365 ? 93.435  132.671 176.581 1.00 46.10  ? 336 ARG B NH1   1 
ATOM   8184  N NH2   . ARG D 1 365 ? 94.630  133.916 175.077 1.00 46.10  ? 336 ARG B NH2   1 
ATOM   8185  N N     . GLY D 1 366 ? 89.841  128.461 173.147 1.00 47.47  ? 337 GLY B N     1 
ATOM   8186  C CA    . GLY D 1 366 ? 88.618  128.330 172.380 1.00 47.47  ? 337 GLY B CA    1 
ATOM   8187  C C     . GLY D 1 366 ? 88.572  129.206 171.146 1.00 47.47  ? 337 GLY B C     1 
ATOM   8188  O O     . GLY D 1 366 ? 88.613  128.700 170.020 1.00 47.47  ? 337 GLY B O     1 
ATOM   8189  N N     . VAL D 1 367 ? 88.478  130.519 171.353 1.00 51.78  ? 338 VAL B N     1 
ATOM   8190  C CA    . VAL D 1 367 ? 88.516  131.520 170.292 1.00 51.78  ? 338 VAL B CA    1 
ATOM   8191  C C     . VAL D 1 367 ? 89.569  132.543 170.680 1.00 51.78  ? 338 VAL B C     1 
ATOM   8192  O O     . VAL D 1 367 ? 89.630  132.966 171.840 1.00 51.78  ? 338 VAL B O     1 
ATOM   8193  C CB    . VAL D 1 367 ? 87.147  132.203 170.079 1.00 51.78  ? 338 VAL B CB    1 
ATOM   8194  C CG1   . VAL D 1 367 ? 87.267  133.330 169.060 1.00 51.78  ? 338 VAL B CG1   1 
ATOM   8195  C CG2   . VAL D 1 367 ? 86.093  131.194 169.627 1.00 51.78  ? 338 VAL B CG2   1 
ATOM   8196  N N     . CYS D 1 368 ? 90.400  132.936 169.715 1.00 53.94  ? 339 CYS B N     1 
ATOM   8197  C CA    . CYS D 1 368 ? 91.560  133.764 170.013 1.00 53.94  ? 339 CYS B CA    1 
ATOM   8198  C C     . CYS D 1 368 ? 91.894  134.626 168.808 1.00 53.94  ? 339 CYS B C     1 
ATOM   8199  O O     . CYS D 1 368 ? 91.600  134.266 167.667 1.00 53.94  ? 339 CYS B O     1 
ATOM   8200  C CB    . CYS D 1 368 ? 92.756  132.893 170.415 1.00 53.94  ? 339 CYS B CB    1 
ATOM   8201  S SG    . CYS D 1 368 ? 94.344  133.742 170.458 1.00 53.94  ? 339 CYS B SG    1 
ATOM   8202  N N     . ASN D 1 369 ? 92.485  135.786 169.081 1.00 58.20  ? 340 ASN B N     1 
ATOM   8203  C CA    . ASN D 1 369 ? 92.953  136.672 168.026 1.00 58.20  ? 340 ASN B CA    1 
ATOM   8204  C C     . ASN D 1 369 ? 94.297  136.180 167.512 1.00 58.20  ? 340 ASN B C     1 
ATOM   8205  O O     . ASN D 1 369 ? 95.234  135.986 168.292 1.00 58.20  ? 340 ASN B O     1 
ATOM   8206  C CB    . ASN D 1 369 ? 93.082  138.104 168.547 1.00 58.20  ? 340 ASN B CB    1 
ATOM   8207  C CG    . ASN D 1 369 ? 91.741  138.801 168.693 1.00 58.20  ? 340 ASN B CG    1 
ATOM   8208  O OD1   . ASN D 1 369 ? 90.852  138.645 167.858 1.00 58.20  ? 340 ASN B OD1   1 
ATOM   8209  N ND2   . ASN D 1 369 ? 91.593  139.579 169.759 1.00 58.20  ? 340 ASN B ND2   1 
ATOM   8210  N N     . VAL D 1 370 ? 94.393  135.983 166.198 1.00 57.25  ? 341 VAL B N     1 
ATOM   8211  C CA    . VAL D 1 370 ? 95.659  135.576 165.601 1.00 57.25  ? 341 VAL B CA    1 
ATOM   8212  C C     . VAL D 1 370 ? 96.651  136.719 165.748 1.00 57.25  ? 341 VAL B C     1 
ATOM   8213  O O     . VAL D 1 370 ? 96.326  137.880 165.466 1.00 57.25  ? 341 VAL B O     1 
ATOM   8214  C CB    . VAL D 1 370 ? 95.475  135.175 164.127 1.00 57.25  ? 341 VAL B CB    1 
ATOM   8215  C CG1   . VAL D 1 370 ? 96.808  134.688 163.541 1.00 57.25  ? 341 VAL B CG1   1 
ATOM   8216  C CG2   . VAL D 1 370 ? 94.390  134.092 163.974 1.00 57.25  ? 341 VAL B CG2   1 
ATOM   8217  N N     . ARG D 1 371 ? 97.854  136.399 166.218 1.00 59.54  ? 342 ARG B N     1 
ATOM   8218  C CA    . ARG D 1 371 ? 98.853  137.424 166.486 1.00 59.54  ? 342 ARG B CA    1 
ATOM   8219  C C     . ARG D 1 371 ? 99.277  138.108 165.193 1.00 59.54  ? 342 ARG B C     1 
ATOM   8220  O O     . ARG D 1 371 ? 99.485  137.457 164.166 1.00 59.54  ? 342 ARG B O     1 
ATOM   8221  C CB    . ARG D 1 371 ? 100.067 136.816 167.189 1.00 59.54  ? 342 ARG B CB    1 
ATOM   8222  C CG    . ARG D 1 371 ? 99.923  136.774 168.710 1.00 59.54  ? 342 ARG B CG    1 
ATOM   8223  C CD    . ARG D 1 371 ? 101.074 136.046 169.400 1.00 59.54  ? 342 ARG B CD    1 
ATOM   8224  N NE    . ARG D 1 371 ? 102.390 136.504 168.965 1.00 59.54  ? 342 ARG B NE    1 
ATOM   8225  C CZ    . ARG D 1 371 ? 102.933 137.681 169.257 1.00 59.54  ? 342 ARG B CZ    1 
ATOM   8226  N NH1   . ARG D 1 371 ? 102.310 138.577 170.012 1.00 59.54  ? 342 ARG B NH1   1 
ATOM   8227  N NH2   . ARG D 1 371 ? 104.140 137.970 168.780 1.00 59.54  ? 342 ARG B NH2   1 
ATOM   8228  N N     . GLY D 1 372 ? 99.392  139.435 165.252 1.00 65.79  ? 343 GLY B N     1 
ATOM   8229  C CA    . GLY D 1 372 ? 99.614  140.259 164.083 1.00 65.79  ? 343 GLY B CA    1 
ATOM   8230  C C     . GLY D 1 372 ? 98.357  140.772 163.406 1.00 65.79  ? 343 GLY B C     1 
ATOM   8231  O O     . GLY D 1 372 ? 98.470  141.586 162.480 1.00 65.79  ? 343 GLY B O     1 
ATOM   8232  N N     . THR D 1 373 ? 97.171  140.315 163.821 1.00 66.08  ? 344 THR B N     1 
ATOM   8233  C CA    . THR D 1 373 ? 95.894  140.813 163.321 1.00 66.08  ? 344 THR B CA    1 
ATOM   8234  C C     . THR D 1 373 ? 94.952  141.013 164.499 1.00 66.08  ? 344 THR B C     1 
ATOM   8235  O O     . THR D 1 373 ? 95.244  140.614 165.630 1.00 66.08  ? 344 THR B O     1 
ATOM   8236  C CB    . THR D 1 373 ? 95.244  139.857 162.308 1.00 66.08  ? 344 THR B CB    1 
ATOM   8237  O OG1   . THR D 1 373 ? 94.578  138.799 163.008 1.00 66.08  ? 344 THR B OG1   1 
ATOM   8238  C CG2   . THR D 1 373 ? 96.274  139.263 161.355 1.00 66.08  ? 344 THR B CG2   1 
ATOM   8239  N N     . ASP D 1 374 ? 93.809  141.647 164.214 1.00 76.70  ? 345 ASP B N     1 
ATOM   8240  C CA    . ASP D 1 374 ? 92.725  141.856 165.169 1.00 76.70  ? 345 ASP B CA    1 
ATOM   8241  C C     . ASP D 1 374 ? 91.478  141.054 164.795 1.00 76.70  ? 345 ASP B C     1 
ATOM   8242  O O     . ASP D 1 374 ? 90.356  141.464 165.102 1.00 76.70  ? 345 ASP B O     1 
ATOM   8243  C CB    . ASP D 1 374 ? 92.391  143.344 165.272 1.00 76.70  ? 345 ASP B CB    1 
ATOM   8244  C CG    . ASP D 1 374 ? 93.565  144.173 165.753 1.00 76.70  ? 345 ASP B CG    1 
ATOM   8245  O OD1   . ASP D 1 374 ? 94.604  143.582 166.118 1.00 76.70  ? 345 ASP B OD1   1 
ATOM   8246  O OD2   . ASP D 1 374 ? 93.448  145.417 165.766 1.00 76.70  ? 345 ASP B OD2   1 
ATOM   8247  N N     . MET D 1 375 ? 91.667  139.904 164.136 1.00 67.23  ? 346 MET B N     1 
ATOM   8248  C CA    . MET D 1 375 ? 90.579  139.032 163.721 1.00 67.23  ? 346 MET B CA    1 
ATOM   8249  C C     . MET D 1 375 ? 90.473  137.891 164.727 1.00 67.23  ? 346 MET B C     1 
ATOM   8250  O O     . MET D 1 375 ? 91.412  137.086 164.820 1.00 67.23  ? 346 MET B O     1 
ATOM   8251  C CB    . MET D 1 375 ? 90.849  138.484 162.318 1.00 67.23  ? 346 MET B CB    1 
ATOM   8252  C CG    . MET D 1 375 ? 89.720  137.655 161.678 1.00 67.23  ? 346 MET B CG    1 
ATOM   8253  S SD    . MET D 1 375 ? 88.474  138.650 160.829 1.00 67.23  ? 346 MET B SD    1 
ATOM   8254  C CE    . MET D 1 375 ? 87.300  138.991 162.141 1.00 67.23  ? 346 MET B CE    1 
ATOM   8255  N N     . PRO D 1 376 ? 89.394  137.775 165.512 1.00 61.79  ? 347 PRO B N     1 
ATOM   8256  C CA    . PRO D 1 376 ? 89.179  136.520 166.244 1.00 61.79  ? 347 PRO B CA    1 
ATOM   8257  C C     . PRO D 1 376 ? 89.002  135.361 165.278 1.00 61.79  ? 347 PRO B C     1 
ATOM   8258  O O     . PRO D 1 376 ? 88.429  135.518 164.197 1.00 61.79  ? 347 PRO B O     1 
ATOM   8259  C CB    . PRO D 1 376 ? 87.901  136.784 167.048 1.00 61.79  ? 347 PRO B CB    1 
ATOM   8260  C CG    . PRO D 1 376 ? 87.818  138.242 167.172 1.00 61.79  ? 347 PRO B CG    1 
ATOM   8261  C CD    . PRO D 1 376 ? 88.423  138.806 165.928 1.00 61.79  ? 347 PRO B CD    1 
ATOM   8262  N N     . SER D 1 377 ? 89.517  134.199 165.669 1.00 51.57  ? 348 SER B N     1 
ATOM   8263  C CA    . SER D 1 377 ? 89.390  132.977 164.890 1.00 51.57  ? 348 SER B CA    1 
ATOM   8264  C C     . SER D 1 377 ? 89.332  131.801 165.854 1.00 51.57  ? 348 SER B C     1 
ATOM   8265  O O     . SER D 1 377 ? 89.754  131.924 167.012 1.00 51.57  ? 348 SER B O     1 
ATOM   8266  C CB    . SER D 1 377 ? 90.559  132.811 163.911 1.00 51.57  ? 348 SER B CB    1 
ATOM   8267  O OG    . SER D 1 377 ? 91.734  132.393 164.582 1.00 51.57  ? 348 SER B OG    1 
ATOM   8268  N N     . PRO D 1 378 ? 88.816  130.645 165.417 1.00 45.42  ? 349 PRO B N     1 
ATOM   8269  C CA    . PRO D 1 378 ? 88.830  129.475 166.304 1.00 45.42  ? 349 PRO B CA    1 
ATOM   8270  C C     . PRO D 1 378 ? 90.250  128.974 166.522 1.00 45.42  ? 349 PRO B C     1 
ATOM   8271  O O     . PRO D 1 378 ? 91.031  128.852 165.577 1.00 45.42  ? 349 PRO B O     1 
ATOM   8272  C CB    . PRO D 1 378 ? 87.981  128.442 165.552 1.00 45.42  ? 349 PRO B CB    1 
ATOM   8273  C CG    . PRO D 1 378 ? 87.226  129.216 164.553 1.00 45.42  ? 349 PRO B CG    1 
ATOM   8274  C CD    . PRO D 1 378 ? 88.132  130.315 164.152 1.00 45.42  ? 349 PRO B CD    1 
ATOM   8275  N N     . HIS D 1 379 ? 90.583  128.708 167.784 1.00 43.04  ? 350 HIS B N     1 
ATOM   8276  C CA    . HIS D 1 379 ? 91.850  128.094 168.180 1.00 43.04  ? 350 HIS B CA    1 
ATOM   8277  C C     . HIS D 1 379 ? 93.068  128.956 167.852 1.00 43.04  ? 350 HIS B C     1 
ATOM   8278  O O     . HIS D 1 379 ? 94.194  128.452 167.833 1.00 43.04  ? 350 HIS B O     1 
ATOM   8279  C CB    . HIS D 1 379 ? 92.008  126.712 167.539 1.00 43.04  ? 350 HIS B CB    1 
ATOM   8280  C CG    . HIS D 1 379 ? 90.839  125.806 167.766 1.00 43.04  ? 350 HIS B CG    1 
ATOM   8281  N ND1   . HIS D 1 379 ? 90.278  125.616 169.009 1.00 43.04  ? 350 HIS B ND1   1 
ATOM   8282  C CD2   . HIS D 1 379 ? 90.127  125.037 166.910 1.00 43.04  ? 350 HIS B CD2   1 
ATOM   8283  C CE1   . HIS D 1 379 ? 89.270  124.769 168.910 1.00 43.04  ? 350 HIS B CE1   1 
ATOM   8284  N NE2   . HIS D 1 379 ? 89.158  124.402 167.647 1.00 43.04  ? 350 HIS B NE2   1 
ATOM   8285  N N     . GLY D 1 380 ? 92.886  130.251 167.598 1.00 47.95  ? 351 GLY B N     1 
ATOM   8286  C CA    . GLY D 1 380 ? 93.999  131.092 167.210 1.00 47.95  ? 351 GLY B CA    1 
ATOM   8287  C C     . GLY D 1 380 ? 94.618  130.776 165.867 1.00 47.95  ? 351 GLY B C     1 
ATOM   8288  O O     . GLY D 1 380 ? 95.718  131.265 165.592 1.00 47.95  ? 351 GLY B O     1 
ATOM   8289  N N     . VAL D 1 381 ? 93.945  129.991 165.025 1.00 46.05  ? 352 VAL B N     1 
ATOM   8290  C CA    . VAL D 1 381 ? 94.443  129.556 163.720 1.00 46.05  ? 352 VAL B CA    1 
ATOM   8291  C C     . VAL D 1 381 ? 93.662  130.349 162.671 1.00 46.05  ? 352 VAL B C     1 
ATOM   8292  O O     . VAL D 1 381 ? 92.458  130.566 162.864 1.00 46.05  ? 352 VAL B O     1 
ATOM   8293  C CB    . VAL D 1 381 ? 94.272  128.037 163.540 1.00 46.05  ? 352 VAL B CB    1 
ATOM   8294  C CG1   . VAL D 1 381 ? 94.955  127.541 162.264 1.00 46.05  ? 352 VAL B CG1   1 
ATOM   8295  C CG2   . VAL D 1 381 ? 94.815  127.288 164.756 1.00 46.05  ? 352 VAL B CG2   1 
ATOM   8296  N N     . PRO D 1 382 ? 94.257  130.802 161.562 1.00 48.13  ? 353 PRO B N     1 
ATOM   8297  C CA    . PRO D 1 382 ? 93.469  131.541 160.571 1.00 48.13  ? 353 PRO B CA    1 
ATOM   8298  C C     . PRO D 1 382 ? 92.531  130.627 159.799 1.00 48.13  ? 353 PRO B C     1 
ATOM   8299  O O     . PRO D 1 382 ? 92.609  129.399 159.855 1.00 48.13  ? 353 PRO B O     1 
ATOM   8300  C CB    . PRO D 1 382 ? 94.529  132.152 159.656 1.00 48.13  ? 353 PRO B CB    1 
ATOM   8301  C CG    . PRO D 1 382 ? 95.680  131.250 159.777 1.00 48.13  ? 353 PRO B CG    1 
ATOM   8302  C CD    . PRO D 1 382 ? 95.686  130.827 161.199 1.00 48.13  ? 353 PRO B CD    1 
ATOM   8303  N N     . ILE D 1 383 ? 91.622  131.265 159.059 1.00 47.40  ? 354 ILE B N     1 
ATOM   8304  C CA    . ILE D 1 383 ? 90.620  130.521 158.306 1.00 47.40  ? 354 ILE B CA    1 
ATOM   8305  C C     . ILE D 1 383 ? 91.249  129.818 157.109 1.00 47.40  ? 354 ILE B C     1 
ATOM   8306  O O     . ILE D 1 383 ? 90.782  128.748 156.701 1.00 47.40  ? 354 ILE B O     1 
ATOM   8307  C CB    . ILE D 1 383 ? 89.485  131.473 157.867 1.00 47.40  ? 354 ILE B CB    1 
ATOM   8308  C CG1   . ILE D 1 383 ? 88.748  132.113 159.070 1.00 47.40  ? 354 ILE B CG1   1 
ATOM   8309  C CG2   . ILE D 1 383 ? 88.499  130.733 156.933 1.00 47.40  ? 354 ILE B CG2   1 
ATOM   8310  C CD1   . ILE D 1 383 ? 88.340  131.199 160.221 1.00 47.40  ? 354 ILE B CD1   1 
ATOM   8311  N N     . ASP D 1 384 ? 92.291  130.403 156.511 1.00 48.48  ? 355 ASP B N     1 
ATOM   8312  C CA    . ASP D 1 384 ? 92.883  129.796 155.320 1.00 48.48  ? 355 ASP B CA    1 
ATOM   8313  C C     . ASP D 1 384 ? 93.547  128.456 155.628 1.00 48.48  ? 355 ASP B C     1 
ATOM   8314  O O     . ASP D 1 384 ? 93.474  127.535 154.807 1.00 48.48  ? 355 ASP B O     1 
ATOM   8315  C CB    . ASP D 1 384 ? 93.881  130.758 154.661 1.00 48.48  ? 355 ASP B CB    1 
ATOM   8316  C CG    . ASP D 1 384 ? 95.000  131.201 155.594 1.00 48.48  ? 355 ASP B CG    1 
ATOM   8317  O OD1   . ASP D 1 384 ? 95.016  130.782 156.767 1.00 48.48  ? 355 ASP B OD1   1 
ATOM   8318  O OD2   . ASP D 1 384 ? 95.866  131.982 155.149 1.00 48.48  ? 355 ASP B OD2   1 
ATOM   8319  N N     . LEU D 1 385 ? 94.181  128.326 156.797 1.00 45.79  ? 356 LEU B N     1 
ATOM   8320  C CA    . LEU D 1 385 ? 94.785  127.066 157.218 1.00 45.79  ? 356 LEU B CA    1 
ATOM   8321  C C     . LEU D 1 385 ? 93.807  126.141 157.930 1.00 45.79  ? 356 LEU B C     1 
ATOM   8322  O O     . LEU D 1 385 ? 94.040  124.928 157.955 1.00 45.79  ? 356 LEU B O     1 
ATOM   8323  C CB    . LEU D 1 385 ? 95.981  127.334 158.143 1.00 45.79  ? 356 LEU B CB    1 
ATOM   8324  C CG    . LEU D 1 385 ? 96.755  126.142 158.737 1.00 45.79  ? 356 LEU B CG    1 
ATOM   8325  C CD1   . LEU D 1 385 ? 97.293  125.210 157.654 1.00 45.79  ? 356 LEU B CD1   1 
ATOM   8326  C CD2   . LEU D 1 385 ? 97.880  126.643 159.621 1.00 45.79  ? 356 LEU B CD2   1 
ATOM   8327  N N     . LEU D 1 386 ? 92.728  126.672 158.513 1.00 45.03  ? 357 LEU B N     1 
ATOM   8328  C CA    . LEU D 1 386 ? 91.801  125.832 159.269 1.00 45.03  ? 357 LEU B CA    1 
ATOM   8329  C C     . LEU D 1 386 ? 91.045  124.839 158.394 1.00 45.03  ? 357 LEU B C     1 
ATOM   8330  O O     . LEU D 1 386 ? 90.508  123.861 158.925 1.00 45.03  ? 357 LEU B O     1 
ATOM   8331  C CB    . LEU D 1 386 ? 90.788  126.691 160.033 1.00 45.03  ? 357 LEU B CB    1 
ATOM   8332  C CG    . LEU D 1 386 ? 91.139  126.961 161.497 1.00 45.03  ? 357 LEU B CG    1 
ATOM   8333  C CD1   . LEU D 1 386 ? 90.397  128.178 162.007 1.00 45.03  ? 357 LEU B CD1   1 
ATOM   8334  C CD2   . LEU D 1 386 ? 90.817  125.754 162.363 1.00 45.03  ? 357 LEU B CD2   1 
ATOM   8335  N N     . ASP D 1 387 ? 90.976  125.068 157.081 1.00 48.68  ? 358 ASP B N     1 
ATOM   8336  C CA    . ASP D 1 387 ? 90.236  124.165 156.206 1.00 48.68  ? 358 ASP B CA    1 
ATOM   8337  C C     . ASP D 1 387 ? 90.873  122.781 156.158 1.00 48.68  ? 358 ASP B C     1 
ATOM   8338  O O     . ASP D 1 387 ? 90.163  121.769 156.149 1.00 48.68  ? 358 ASP B O     1 
ATOM   8339  C CB    . ASP D 1 387 ? 90.155  124.761 154.801 1.00 48.68  ? 358 ASP B CB    1 
ATOM   8340  C CG    . ASP D 1 387 ? 89.190  125.928 154.713 1.00 48.68  ? 358 ASP B CG    1 
ATOM   8341  O OD1   . ASP D 1 387 ? 88.691  126.379 155.766 1.00 48.68  ? 358 ASP B OD1   1 
ATOM   8342  O OD2   . ASP D 1 387 ? 88.931  126.398 153.586 1.00 48.68  ? 358 ASP B OD2   1 
ATOM   8343  N N     . ARG D 1 388 ? 92.208  122.716 156.143 1.00 45.85  ? 359 ARG B N     1 
ATOM   8344  C CA    . ARG D 1 388 ? 92.940  121.468 155.948 1.00 45.85  ? 359 ARG B CA    1 
ATOM   8345  C C     . ARG D 1 388 ? 93.309  120.780 157.261 1.00 45.85  ? 359 ARG B C     1 
ATOM   8346  O O     . ARG D 1 388 ? 94.319  120.064 157.306 1.00 45.85  ? 359 ARG B O     1 
ATOM   8347  C CB    . ARG D 1 388 ? 94.192  121.729 155.103 1.00 45.85  ? 359 ARG B CB    1 
ATOM   8348  C CG    . ARG D 1 388 ? 95.228  122.700 155.698 1.00 45.85  ? 359 ARG B CG    1 
ATOM   8349  C CD    . ARG D 1 388 ? 96.564  122.621 154.965 1.00 45.85  ? 359 ARG B CD    1 
ATOM   8350  N NE    . ARG D 1 388 ? 96.407  122.595 153.515 1.00 45.85  ? 359 ARG B NE    1 
ATOM   8351  C CZ    . ARG D 1 388 ? 95.980  123.608 152.767 1.00 45.85  ? 359 ARG B CZ    1 
ATOM   8352  N NH1   . ARG D 1 388 ? 95.696  124.796 153.284 1.00 45.85  ? 359 ARG B NH1   1 
ATOM   8353  N NH2   . ARG D 1 388 ? 95.843  123.428 151.457 1.00 45.85  ? 359 ARG B NH2   1 
ATOM   8354  N N     . LEU D 1 389 ? 92.516  120.973 158.319 1.00 39.99  ? 360 LEU B N     1 
ATOM   8355  C CA    . LEU D 1 389 ? 92.794  120.446 159.652 1.00 39.99  ? 360 LEU B CA    1 
ATOM   8356  C C     . LEU D 1 389 ? 91.723  119.438 160.036 1.00 39.99  ? 360 LEU B C     1 
ATOM   8357  O O     . LEU D 1 389 ? 90.535  119.773 160.070 1.00 39.99  ? 360 LEU B O     1 
ATOM   8358  C CB    . LEU D 1 389 ? 92.848  121.573 160.687 1.00 39.99  ? 360 LEU B CB    1 
ATOM   8359  C CG    . LEU D 1 389 ? 94.120  122.432 160.761 1.00 39.99  ? 360 LEU B CG    1 
ATOM   8360  C CD1   . LEU D 1 389 ? 93.955  123.622 161.701 1.00 39.99  ? 360 LEU B CD1   1 
ATOM   8361  C CD2   . LEU D 1 389 ? 95.323  121.614 161.205 1.00 39.99  ? 360 LEU B CD2   1 
ATOM   8362  N N     . VAL D 1 390 ? 92.148  118.212 160.327 1.00 39.62  ? 361 VAL B N     1 
ATOM   8363  C CA    . VAL D 1 390 ? 91.301  117.213 160.968 1.00 39.62  ? 361 VAL B CA    1 
ATOM   8364  C C     . VAL D 1 390 ? 91.415  117.442 162.468 1.00 39.62  ? 361 VAL B C     1 
ATOM   8365  O O     . VAL D 1 390 ? 92.523  117.449 163.013 1.00 39.62  ? 361 VAL B O     1 
ATOM   8366  C CB    . VAL D 1 390 ? 91.733  115.789 160.583 1.00 39.62  ? 361 VAL B CB    1 
ATOM   8367  C CG1   . VAL D 1 390 ? 90.708  114.748 161.052 1.00 39.62  ? 361 VAL B CG1   1 
ATOM   8368  C CG2   . VAL D 1 390 ? 91.950  115.690 159.080 1.00 39.62  ? 361 VAL B CG2   1 
ATOM   8369  N N     . ILE D 1 391 ? 90.275  117.624 163.135 1.00 36.27  ? 362 ILE B N     1 
ATOM   8370  C CA    . ILE D 1 391 ? 90.218  118.053 164.529 1.00 36.27  ? 362 ILE B CA    1 
ATOM   8371  C C     . ILE D 1 391 ? 89.806  116.855 165.373 1.00 36.27  ? 362 ILE B C     1 
ATOM   8372  O O     . ILE D 1 391 ? 88.936  116.074 164.973 1.00 36.27  ? 362 ILE B O     1 
ATOM   8373  C CB    . ILE D 1 391 ? 89.250  119.241 164.718 1.00 36.27  ? 362 ILE B CB    1 
ATOM   8374  C CG1   . ILE D 1 391 ? 89.511  120.306 163.637 1.00 36.27  ? 362 ILE B CG1   1 
ATOM   8375  C CG2   . ILE D 1 391 ? 89.408  119.881 166.117 1.00 36.27  ? 362 ILE B CG2   1 
ATOM   8376  C CD1   . ILE D 1 391 ? 88.846  121.650 163.862 1.00 36.27  ? 362 ILE B CD1   1 
ATOM   8377  N N     . ILE D 1 392 ? 90.448  116.710 166.535 1.00 39.49  ? 363 ILE B N     1 
ATOM   8378  C CA    . ILE D 1 392 ? 90.176  115.645 167.496 1.00 39.49  ? 363 ILE B CA    1 
ATOM   8379  C C     . ILE D 1 392 ? 89.899  116.285 168.848 1.00 39.49  ? 363 ILE B C     1 
ATOM   8380  O O     . ILE D 1 392 ? 90.569  117.248 169.238 1.00 39.49  ? 363 ILE B O     1 
ATOM   8381  C CB    . ILE D 1 392 ? 91.343  114.635 167.619 1.00 39.49  ? 363 ILE B CB    1 
ATOM   8382  C CG1   . ILE D 1 392 ? 92.011  114.329 166.266 1.00 39.49  ? 363 ILE B CG1   1 
ATOM   8383  C CG2   . ILE D 1 392 ? 90.873  113.349 168.294 1.00 39.49  ? 363 ILE B CG2   1 
ATOM   8384  C CD1   . ILE D 1 392 ? 91.111  113.708 165.210 1.00 39.49  ? 363 ILE B CD1   1 
ATOM   8385  N N     . ARG D 1 393 ? 88.916  115.741 169.561 1.00 40.28  ? 364 ARG B N     1 
ATOM   8386  C CA    . ARG D 1 393 ? 88.505  116.217 170.876 1.00 40.28  ? 364 ARG B CA    1 
ATOM   8387  C C     . ARG D 1 393 ? 89.062  115.268 171.929 1.00 40.28  ? 364 ARG B C     1 
ATOM   8388  O O     . ARG D 1 393 ? 88.914  114.047 171.805 1.00 40.28  ? 364 ARG B O     1 
ATOM   8389  C CB    . ARG D 1 393 ? 86.973  116.298 170.947 1.00 40.28  ? 364 ARG B CB    1 
ATOM   8390  C CG    . ARG D 1 393 ? 86.319  116.641 172.306 1.00 40.28  ? 364 ARG B CG    1 
ATOM   8391  C CD    . ARG D 1 393 ? 86.398  118.123 172.627 1.00 40.28  ? 364 ARG B CD    1 
ATOM   8392  N NE    . ARG D 1 393 ? 86.103  118.378 174.034 1.00 40.28  ? 364 ARG B NE    1 
ATOM   8393  C CZ    . ARG D 1 393 ? 86.370  119.500 174.692 1.00 40.28  ? 364 ARG B CZ    1 
ATOM   8394  N NH1   . ARG D 1 393 ? 86.918  120.551 174.098 1.00 40.28  ? 364 ARG B NH1   1 
ATOM   8395  N NH2   . ARG D 1 393 ? 86.069  119.576 175.985 1.00 40.28  ? 364 ARG B NH2   1 
ATOM   8396  N N     . THR D 1 394 ? 89.700  115.834 172.953 1.00 33.28  ? 365 THR B N     1 
ATOM   8397  C CA    . THR D 1 394 ? 90.197  115.101 174.110 1.00 33.28  ? 365 THR B CA    1 
ATOM   8398  C C     . THR D 1 394 ? 89.417  115.524 175.348 1.00 33.28  ? 365 THR B C     1 
ATOM   8399  O O     . THR D 1 394 ? 89.175  116.716 175.562 1.00 33.28  ? 365 THR B O     1 
ATOM   8400  C CB    . THR D 1 394 ? 91.692  115.348 174.318 1.00 33.28  ? 365 THR B CB    1 
ATOM   8401  O OG1   . THR D 1 394 ? 91.938  116.753 174.427 1.00 33.28  ? 365 THR B OG1   1 
ATOM   8402  C CG2   . THR D 1 394 ? 92.491  114.788 173.156 1.00 33.28  ? 365 THR B CG2   1 
ATOM   8403  N N     . GLN D 1 395 ? 89.033  114.542 176.159 1.00 32.41  ? 366 GLN B N     1 
ATOM   8404  C CA    . GLN D 1 395 ? 88.128  114.738 177.283 1.00 32.41  ? 366 GLN B CA    1 
ATOM   8405  C C     . GLN D 1 395 ? 88.906  114.907 178.582 1.00 32.41  ? 366 GLN B C     1 
ATOM   8406  O O     . GLN D 1 395 ? 89.977  114.324 178.767 1.00 32.41  ? 366 GLN B O     1 
ATOM   8407  C CB    . GLN D 1 395 ? 87.161  113.554 177.438 1.00 32.41  ? 366 GLN B CB    1 
ATOM   8408  C CG    . GLN D 1 395 ? 86.518  113.002 176.157 1.00 32.41  ? 366 GLN B CG    1 
ATOM   8409  C CD    . GLN D 1 395 ? 85.506  113.947 175.548 1.00 32.41  ? 366 GLN B CD    1 
ATOM   8410  O OE1   . GLN D 1 395 ? 85.388  115.101 175.957 1.00 32.41  ? 366 GLN B OE1   1 
ATOM   8411  N NE2   . GLN D 1 395 ? 84.765  113.460 174.561 1.00 32.41  ? 366 GLN B NE2   1 
ATOM   8412  N N     . ILE D 1 396 ? 88.355  115.729 179.480 1.00 31.86  ? 367 ILE B N     1 
ATOM   8413  C CA    . ILE D 1 396 ? 88.855  115.740 180.864 1.00 31.86  ? 367 ILE B CA    1 
ATOM   8414  C C     . ILE D 1 396 ? 88.623  114.353 181.465 1.00 31.86  ? 367 ILE B C     1 
ATOM   8415  O O     . ILE D 1 396 ? 87.739  113.597 181.044 1.00 31.86  ? 367 ILE B O     1 
ATOM   8416  C CB    . ILE D 1 396 ? 88.236  116.814 181.781 1.00 31.86  ? 367 ILE B CB    1 
ATOM   8417  C CG1   . ILE D 1 396 ? 86.746  117.074 181.492 1.00 31.86  ? 367 ILE B CG1   1 
ATOM   8418  C CG2   . ILE D 1 396 ? 89.042  118.109 181.669 1.00 31.86  ? 367 ILE B CG2   1 
ATOM   8419  C CD1   . ILE D 1 396 ? 86.008  117.832 182.582 1.00 31.86  ? 367 ILE B CD1   1 
ATOM   8420  N N     . TYR D 1 397 ? 89.420  114.030 182.481 1.00 32.88  ? 368 TYR B N     1 
ATOM   8421  C CA    . TYR D 1 397 ? 89.498  112.676 183.009 1.00 32.88  ? 368 TYR B CA    1 
ATOM   8422  C C     . TYR D 1 397 ? 88.553  112.473 184.186 1.00 32.88  ? 368 TYR B C     1 
ATOM   8423  O O     . TYR D 1 397 ? 88.255  113.399 184.944 1.00 32.88  ? 368 TYR B O     1 
ATOM   8424  C CB    . TYR D 1 397 ? 90.924  112.359 183.463 1.00 32.88  ? 368 TYR B CB    1 
ATOM   8425  C CG    . TYR D 1 397 ? 91.917  112.166 182.343 1.00 32.88  ? 368 TYR B CG    1 
ATOM   8426  C CD1   . TYR D 1 397 ? 91.804  111.106 181.456 1.00 32.88  ? 368 TYR B CD1   1 
ATOM   8427  C CD2   . TYR D 1 397 ? 92.980  113.037 182.186 1.00 32.88  ? 368 TYR B CD2   1 
ATOM   8428  C CE1   . TYR D 1 397 ? 92.710  110.930 180.439 1.00 32.88  ? 368 TYR B CE1   1 
ATOM   8429  C CE2   . TYR D 1 397 ? 93.892  112.865 181.175 1.00 32.88  ? 368 TYR B CE2   1 
ATOM   8430  C CZ    . TYR D 1 397 ? 93.752  111.813 180.304 1.00 32.88  ? 368 TYR B CZ    1 
ATOM   8431  O OH    . TYR D 1 397 ? 94.661  111.645 179.291 1.00 32.88  ? 368 TYR B OH    1 
ATOM   8432  N N     . ASP D 1 398 ? 88.085  111.235 184.327 1.00 38.48  ? 369 ASP B N     1 
ATOM   8433  C CA    . ASP D 1 398 ? 87.423  110.808 185.542 1.00 38.48  ? 369 ASP B CA    1 
ATOM   8434  C C     . ASP D 1 398 ? 88.480  110.726 186.651 1.00 38.48  ? 369 ASP B C     1 
ATOM   8435  O O     . ASP D 1 398 ? 89.673  110.636 186.350 1.00 38.48  ? 369 ASP B O     1 
ATOM   8436  C CB    . ASP D 1 398 ? 86.730  109.463 185.298 1.00 38.48  ? 369 ASP B CB    1 
ATOM   8437  C CG    . ASP D 1 398 ? 86.124  108.856 186.553 1.00 38.48  ? 369 ASP B CG    1 
ATOM   8438  O OD1   . ASP D 1 398 ? 86.874  108.278 187.366 1.00 38.48  ? 369 ASP B OD1   1 
ATOM   8439  O OD2   . ASP D 1 398 ? 84.892  108.958 186.725 1.00 38.48  ? 369 ASP B OD2   1 
ATOM   8440  N N     . PRO D 1 399 ? 88.086  110.835 187.939 1.00 39.10  ? 370 PRO B N     1 
ATOM   8441  C CA    . PRO D 1 399 ? 89.059  110.593 189.022 1.00 39.10  ? 370 PRO B CA    1 
ATOM   8442  C C     . PRO D 1 399 ? 89.820  109.277 188.942 1.00 39.10  ? 370 PRO B C     1 
ATOM   8443  O O     . PRO D 1 399 ? 91.031  109.269 189.186 1.00 39.10  ? 370 PRO B O     1 
ATOM   8444  C CB    . PRO D 1 399 ? 88.159  110.619 190.272 1.00 39.10  ? 370 PRO B CB    1 
ATOM   8445  C CG    . PRO D 1 399 ? 86.825  111.237 189.777 1.00 39.10  ? 370 PRO B CG    1 
ATOM   8446  C CD    . PRO D 1 399 ? 87.167  111.849 188.474 1.00 39.10  ? 370 PRO B CD    1 
ATOM   8447  N N     . SER D 1 400 ? 89.157  108.173 188.591 1.00 39.13  ? 371 SER B N     1 
ATOM   8448  C CA    . SER D 1 400 ? 89.850  106.889 188.525 1.00 39.13  ? 371 SER B CA    1 
ATOM   8449  C C     . SER D 1 400 ? 90.890  106.865 187.411 1.00 39.13  ? 371 SER B C     1 
ATOM   8450  O O     . SER D 1 400 ? 91.953  106.250 187.565 1.00 39.13  ? 371 SER B O     1 
ATOM   8451  C CB    . SER D 1 400 ? 88.839  105.761 188.330 1.00 39.13  ? 371 SER B CB    1 
ATOM   8452  O OG    . SER D 1 400 ? 89.473  104.497 188.390 1.00 39.13  ? 371 SER B OG    1 
ATOM   8453  N N     . GLU D 1 401 ? 90.611  107.532 186.291 1.00 39.00  ? 372 GLU B N     1 
ATOM   8454  C CA    . GLU D 1 401 ? 91.593  107.602 185.216 1.00 39.00  ? 372 GLU B CA    1 
ATOM   8455  C C     . GLU D 1 401 ? 92.811  108.421 185.633 1.00 39.00  ? 372 GLU B C     1 
ATOM   8456  O O     . GLU D 1 401 ? 93.947  108.056 185.312 1.00 39.00  ? 372 GLU B O     1 
ATOM   8457  C CB    . GLU D 1 401 ? 90.937  108.171 183.959 1.00 39.00  ? 372 GLU B CB    1 
ATOM   8458  C CG    . GLU D 1 401 ? 90.073  107.141 183.236 1.00 39.00  ? 372 GLU B CG    1 
ATOM   8459  C CD    . GLU D 1 401 ? 89.238  107.731 182.116 1.00 39.00  ? 372 GLU B CD    1 
ATOM   8460  O OE1   . GLU D 1 401 ? 89.351  108.946 181.855 1.00 39.00  ? 372 GLU B OE1   1 
ATOM   8461  O OE2   . GLU D 1 401 ? 88.463  106.974 181.494 1.00 39.00  ? 372 GLU B OE2   1 
ATOM   8462  N N     . MET D 1 402 ? 92.600  109.518 186.366 1.00 36.42  ? 373 MET B N     1 
ATOM   8463  C CA    . MET D 1 402 ? 93.730  110.281 186.890 1.00 36.42  ? 373 MET B CA    1 
ATOM   8464  C C     . MET D 1 402 ? 94.524  109.461 187.898 1.00 36.42  ? 373 MET B C     1 
ATOM   8465  O O     . MET D 1 402 ? 95.757  109.556 187.953 1.00 36.42  ? 373 MET B O     1 
ATOM   8466  C CB    . MET D 1 402 ? 93.239  111.581 187.530 1.00 36.42  ? 373 MET B CB    1 
ATOM   8467  C CG    . MET D 1 402 ? 92.919  112.696 186.543 1.00 36.42  ? 373 MET B CG    1 
ATOM   8468  S SD    . MET D 1 402 ? 93.022  114.330 187.290 1.00 36.42  ? 373 MET B SD    1 
ATOM   8469  C CE    . MET D 1 402 ? 92.097  115.300 186.103 1.00 36.42  ? 373 MET B CE    1 
ATOM   8470  N N     . ILE D 1 403 ? 93.830  108.649 188.700 1.00 39.32  ? 374 ILE B N     1 
ATOM   8471  C CA    . ILE D 1 403 ? 94.500  107.762 189.650 1.00 39.32  ? 374 ILE B CA    1 
ATOM   8472  C C     . ILE D 1 403 ? 95.390  106.776 188.908 1.00 39.32  ? 374 ILE B C     1 
ATOM   8473  O O     . ILE D 1 403 ? 96.540  106.539 189.291 1.00 39.32  ? 374 ILE B O     1 
ATOM   8474  C CB    . ILE D 1 403 ? 93.459  107.033 190.525 1.00 39.32  ? 374 ILE B CB    1 
ATOM   8475  C CG1   . ILE D 1 403 ? 92.799  108.006 191.509 1.00 39.32  ? 374 ILE B CG1   1 
ATOM   8476  C CG2   . ILE D 1 403 ? 94.067  105.820 191.272 1.00 39.32  ? 374 ILE B CG2   1 
ATOM   8477  C CD1   . ILE D 1 403 ? 93.614  108.352 192.701 1.00 39.32  ? 374 ILE B CD1   1 
ATOM   8478  N N     . GLN D 1 404 ? 94.868  106.189 187.831 1.00 36.55  ? 375 GLN B N     1 
ATOM   8479  C CA    . GLN D 1 404 ? 95.651  105.220 187.073 1.00 36.55  ? 375 GLN B CA    1 
ATOM   8480  C C     . GLN D 1 404 ? 96.831  105.884 186.371 1.00 36.55  ? 375 GLN B C     1 
ATOM   8481  O O     . GLN D 1 404 ? 97.912  105.287 186.273 1.00 36.55  ? 375 GLN B O     1 
ATOM   8482  C CB    . GLN D 1 404 ? 94.751  104.495 186.076 1.00 36.55  ? 375 GLN B CB    1 
ATOM   8483  C CG    . GLN D 1 404 ? 93.842  103.473 186.739 1.00 36.55  ? 375 GLN B CG    1 
ATOM   8484  C CD    . GLN D 1 404 ? 92.742  102.981 185.826 1.00 36.55  ? 375 GLN B CD    1 
ATOM   8485  O OE1   . GLN D 1 404 ? 92.741  101.825 185.405 1.00 36.55  ? 375 GLN B OE1   1 
ATOM   8486  N NE2   . GLN D 1 404 ? 91.792  103.854 185.521 1.00 36.55  ? 375 GLN B NE2   1 
ATOM   8487  N N     . ILE D 1 405 ? 96.650  107.122 185.893 1.00 34.89  ? 376 ILE B N     1 
ATOM   8488  C CA    . ILE D 1 405 ? 97.750  107.849 185.254 1.00 34.89  ? 376 ILE B CA    1 
ATOM   8489  C C     . ILE D 1 405 ? 98.862  108.110 186.262 1.00 34.89  ? 376 ILE B C     1 
ATOM   8490  O O     . ILE D 1 405 ? 100.049 107.896 185.977 1.00 34.89  ? 376 ILE B O     1 
ATOM   8491  C CB    . ILE D 1 405 ? 97.248  109.167 184.630 1.00 34.89  ? 376 ILE B CB    1 
ATOM   8492  C CG1   . ILE D 1 405 ? 96.332  108.905 183.434 1.00 34.89  ? 376 ILE B CG1   1 
ATOM   8493  C CG2   . ILE D 1 405 ? 98.432  110.027 184.160 1.00 34.89  ? 376 ILE B CG2   1 
ATOM   8494  C CD1   . ILE D 1 405 ? 95.392  110.047 183.091 1.00 34.89  ? 376 ILE B CD1   1 
ATOM   8495  N N     . ILE D 1 406 ? 98.493  108.589 187.452 1.00 37.39  ? 377 ILE B N     1 
ATOM   8496  C CA    . ILE D 1 406 ? 99.491  108.867 188.479 1.00 37.39  ? 377 ILE B CA    1 
ATOM   8497  C C     . ILE D 1 406 ? 100.159 107.573 188.927 1.00 37.39  ? 377 ILE B C     1 
ATOM   8498  O O     . ILE D 1 406 ? 101.362 107.549 189.209 1.00 37.39  ? 377 ILE B O     1 
ATOM   8499  C CB    . ILE D 1 406 ? 98.852  109.623 189.664 1.00 37.39  ? 377 ILE B CB    1 
ATOM   8500  C CG1   . ILE D 1 406 ? 98.340  111.016 189.248 1.00 37.39  ? 377 ILE B CG1   1 
ATOM   8501  C CG2   . ILE D 1 406 ? 99.841  109.762 190.822 1.00 37.39  ? 377 ILE B CG2   1 
ATOM   8502  C CD1   . ILE D 1 406 ? 99.418  112.080 189.048 1.00 37.39  ? 377 ILE B CD1   1 
ATOM   8503  N N     . ALA D 1 407 ? 99.400  106.475 188.971 1.00 36.79  ? 378 ALA B N     1 
ATOM   8504  C CA    . ALA D 1 407 ? 99.960  105.192 189.378 1.00 36.79  ? 378 ALA B CA    1 
ATOM   8505  C C     . ALA D 1 407 ? 101.007 104.703 188.385 1.00 36.79  ? 378 ALA B C     1 
ATOM   8506  O O     . ALA D 1 407 ? 102.106 104.298 188.783 1.00 36.79  ? 378 ALA B O     1 
ATOM   8507  C CB    . ALA D 1 407 ? 98.842  104.162 189.527 1.00 36.79  ? 378 ALA B CB    1 
ATOM   8508  N N     . ILE D 1 408 ? 100.689 104.731 187.086 1.00 36.87  ? 379 ILE B N     1 
ATOM   8509  C CA    . ILE D 1 408 ? 101.651 104.243 186.098 1.00 36.87  ? 379 ILE B CA    1 
ATOM   8510  C C     . ILE D 1 408 ? 102.857 105.172 186.020 1.00 36.87  ? 379 ILE B C     1 
ATOM   8511  O O     . ILE D 1 408 ? 103.992 104.718 185.824 1.00 36.87  ? 379 ILE B O     1 
ATOM   8512  C CB    . ILE D 1 408 ? 100.994 104.038 184.715 1.00 36.87  ? 379 ILE B CB    1 
ATOM   8513  C CG1   . ILE D 1 408 ? 101.994 103.407 183.739 1.00 36.87  ? 379 ILE B CG1   1 
ATOM   8514  C CG2   . ILE D 1 408 ? 100.466 105.338 184.109 1.00 36.87  ? 379 ILE B CG2   1 
ATOM   8515  C CD1   . ILE D 1 408 ? 101.343 102.658 182.597 1.00 36.87  ? 379 ILE B CD1   1 
ATOM   8516  N N     . ARG D 1 409 ? 102.640 106.483 186.171 1.00 36.48  ? 380 ARG B N     1 
ATOM   8517  C CA    . ARG D 1 409 ? 103.764 107.414 186.145 1.00 36.48  ? 380 ARG B CA    1 
ATOM   8518  C C     . ARG D 1 409 ? 104.683 107.215 187.345 1.00 36.48  ? 380 ARG B C     1 
ATOM   8519  O O     . ARG D 1 409 ? 105.909 107.294 187.210 1.00 36.48  ? 380 ARG B O     1 
ATOM   8520  C CB    . ARG D 1 409 ? 103.253 108.855 186.087 1.00 36.48  ? 380 ARG B CB    1 
ATOM   8521  C CG    . ARG D 1 409 ? 102.811 109.337 184.689 1.00 36.48  ? 380 ARG B CG    1 
ATOM   8522  C CD    . ARG D 1 409 ? 103.930 109.367 183.631 1.00 36.48  ? 380 ARG B CD    1 
ATOM   8523  N NE    . ARG D 1 409 ? 105.213 109.828 184.161 1.00 36.48  ? 380 ARG B NE    1 
ATOM   8524  C CZ    . ARG D 1 409 ? 106.417 109.510 183.695 1.00 36.48  ? 380 ARG B CZ    1 
ATOM   8525  N NH1   . ARG D 1 409 ? 106.582 108.742 182.627 1.00 36.48  ? 380 ARG B NH1   1 
ATOM   8526  N NH2   . ARG D 1 409 ? 107.493 109.983 184.315 1.00 36.48  ? 380 ARG B NH2   1 
ATOM   8527  N N     . ALA D 1 410 ? 104.118 106.961 188.527 1.00 40.15  ? 381 ALA B N     1 
ATOM   8528  C CA    . ALA D 1 410 ? 104.953 106.664 189.684 1.00 40.15  ? 381 ALA B CA    1 
ATOM   8529  C C     . ALA D 1 410 ? 105.674 105.333 189.514 1.00 40.15  ? 381 ALA B C     1 
ATOM   8530  O O     . ALA D 1 410 ? 106.837 105.196 189.909 1.00 40.15  ? 381 ALA B O     1 
ATOM   8531  C CB    . ALA D 1 410 ? 104.105 106.656 190.955 1.00 40.15  ? 381 ALA B CB    1 
ATOM   8532  N N     . GLN D 1 411 ? 104.999 104.341 188.928 1.00 40.35  ? 382 GLN B N     1 
ATOM   8533  C CA    . GLN D 1 411 ? 105.611 103.028 188.745 1.00 40.35  ? 382 GLN B CA    1 
ATOM   8534  C C     . GLN D 1 411 ? 106.781 103.087 187.771 1.00 40.35  ? 382 GLN B C     1 
ATOM   8535  O O     . GLN D 1 411 ? 107.806 102.430 187.987 1.00 40.35  ? 382 GLN B O     1 
ATOM   8536  C CB    . GLN D 1 411 ? 104.554 102.032 188.264 1.00 40.35  ? 382 GLN B CB    1 
ATOM   8537  C CG    . GLN D 1 411 ? 104.993 100.559 188.300 1.00 40.35  ? 382 GLN B CG    1 
ATOM   8538  C CD    . GLN D 1 411 ? 105.664 100.067 187.018 1.00 40.35  ? 382 GLN B CD    1 
ATOM   8539  O OE1   . GLN D 1 411 ? 105.495 100.640 185.941 1.00 40.35  ? 382 GLN B OE1   1 
ATOM   8540  N NE2   . GLN D 1 411 ? 106.435 98.994  187.141 1.00 40.35  ? 382 GLN B NE2   1 
ATOM   8541  N N     . VAL D 1 412 ? 106.650 103.864 186.694 1.00 40.38  ? 383 VAL B N     1 
ATOM   8542  C CA    . VAL D 1 412 ? 107.712 103.905 185.690 1.00 40.38  ? 383 VAL B CA    1 
ATOM   8543  C C     . VAL D 1 412 ? 108.945 104.618 186.238 1.00 40.38  ? 383 VAL B C     1 
ATOM   8544  O O     . VAL D 1 412 ? 110.074 104.300 185.844 1.00 40.38  ? 383 VAL B O     1 
ATOM   8545  C CB    . VAL D 1 412 ? 107.173 104.535 184.385 1.00 40.38  ? 383 VAL B CB    1 
ATOM   8546  C CG1   . VAL D 1 412 ? 108.260 105.248 183.545 1.00 40.38  ? 383 VAL B CG1   1 
ATOM   8547  C CG2   . VAL D 1 412 ? 106.502 103.453 183.559 1.00 40.38  ? 383 VAL B CG2   1 
ATOM   8548  N N     . GLU D 1 413 ? 108.763 105.578 187.144 1.00 42.17  ? 384 GLU B N     1 
ATOM   8549  C CA    . GLU D 1 413 ? 109.877 106.216 187.839 1.00 42.17  ? 384 GLU B CA    1 
ATOM   8550  C C     . GLU D 1 413 ? 110.429 105.377 189.001 1.00 42.17  ? 384 GLU B C     1 
ATOM   8551  O O     . GLU D 1 413 ? 111.305 105.866 189.722 1.00 42.17  ? 384 GLU B O     1 
ATOM   8552  C CB    . GLU D 1 413 ? 109.445 107.598 188.344 1.00 42.17  ? 384 GLU B CB    1 
ATOM   8553  C CG    . GLU D 1 413 ? 109.304 108.635 187.235 1.00 42.17  ? 384 GLU B CG    1 
ATOM   8554  C CD    . GLU D 1 413 ? 109.065 110.040 187.760 1.00 42.17  ? 384 GLU B CD    1 
ATOM   8555  O OE1   . GLU D 1 413 ? 109.727 110.437 188.741 1.00 42.17  ? 384 GLU B OE1   1 
ATOM   8556  O OE2   . GLU D 1 413 ? 108.214 110.751 187.185 1.00 42.17  ? 384 GLU B OE2   1 
ATOM   8557  N N     . GLU D 1 414 ? 109.949 104.143 189.193 1.00 45.09  ? 385 GLU B N     1 
ATOM   8558  C CA    . GLU D 1 414 ? 110.421 103.234 190.238 1.00 45.09  ? 385 GLU B CA    1 
ATOM   8559  C C     . GLU D 1 414 ? 110.156 103.826 191.624 1.00 45.09  ? 385 GLU B C     1 
ATOM   8560  O O     . GLU D 1 414 ? 111.057 103.992 192.448 1.00 45.09  ? 385 GLU B O     1 
ATOM   8561  C CB    . GLU D 1 414 ? 111.909 102.891 190.055 1.00 45.09  ? 385 GLU B CB    1 
ATOM   8562  C CG    . GLU D 1 414 ? 112.363 102.230 188.717 1.00 45.09  ? 385 GLU B CG    1 
ATOM   8563  C CD    . GLU D 1 414 ? 111.652 100.936 188.289 1.00 45.09  ? 385 GLU B CD    1 
ATOM   8564  O OE1   . GLU D 1 414 ? 112.243 100.218 187.457 1.00 45.09  ? 385 GLU B OE1   1 
ATOM   8565  O OE2   . GLU D 1 414 ? 110.544 100.603 188.747 1.00 45.09  ? 385 GLU B OE2   1 
ATOM   8566  N N     . LEU D 1 415 ? 108.884 104.146 191.852 1.00 45.54  ? 386 LEU B N     1 
ATOM   8567  C CA    . LEU D 1 415 ? 108.358 104.563 193.143 1.00 45.54  ? 386 LEU B CA    1 
ATOM   8568  C C     . LEU D 1 415 ? 107.257 103.599 193.559 1.00 45.54  ? 386 LEU B C     1 
ATOM   8569  O O     . LEU D 1 415 ? 106.514 103.086 192.716 1.00 45.54  ? 386 LEU B O     1 
ATOM   8570  C CB    . LEU D 1 415 ? 107.783 105.987 193.089 1.00 45.54  ? 386 LEU B CB    1 
ATOM   8571  C CG    . LEU D 1 415 ? 108.701 107.198 193.283 1.00 45.54  ? 386 LEU B CG    1 
ATOM   8572  C CD1   . LEU D 1 415 ? 110.024 107.036 192.557 1.00 45.54  ? 386 LEU B CD1   1 
ATOM   8573  C CD2   . LEU D 1 415 ? 107.984 108.458 192.811 1.00 45.54  ? 386 LEU B CD2   1 
ATOM   8574  N N     . THR D 1 416 ? 107.172 103.351 194.864 1.00 56.12  ? 387 THR B N     1 
ATOM   8575  C CA    . THR D 1 416 ? 106.063 102.636 195.482 1.00 56.12  ? 387 THR B CA    1 
ATOM   8576  C C     . THR D 1 416 ? 105.246 103.634 196.292 1.00 56.12  ? 387 THR B C     1 
ATOM   8577  O O     . THR D 1 416 ? 105.807 104.520 196.945 1.00 56.12  ? 387 THR B O     1 
ATOM   8578  C CB    . THR D 1 416 ? 106.566 101.474 196.355 1.00 56.12  ? 387 THR B CB    1 
ATOM   8579  O OG1   . THR D 1 416 ? 105.489 100.562 196.609 1.00 56.12  ? 387 THR B OG1   1 
ATOM   8580  C CG2   . THR D 1 416 ? 107.165 101.953 197.677 1.00 56.12  ? 387 THR B CG2   1 
ATOM   8581  N N     . VAL D 1 417 ? 103.923 103.504 196.222 1.00 51.64  ? 388 VAL B N     1 
ATOM   8582  C CA    . VAL D 1 417 ? 103.018 104.561 196.662 1.00 51.64  ? 388 VAL B CA    1 
ATOM   8583  C C     . VAL D 1 417 ? 101.726 103.931 197.170 1.00 51.64  ? 388 VAL B C     1 
ATOM   8584  O O     . VAL D 1 417 ? 101.256 102.923 196.634 1.00 51.64  ? 388 VAL B O     1 
ATOM   8585  C CB    . VAL D 1 417 ? 102.778 105.574 195.514 1.00 51.64  ? 388 VAL B CB    1 
ATOM   8586  C CG1   . VAL D 1 417 ? 102.398 104.868 194.205 1.00 51.64  ? 388 VAL B CG1   1 
ATOM   8587  C CG2   . VAL D 1 417 ? 101.737 106.594 195.901 1.00 51.64  ? 388 VAL B CG2   1 
ATOM   8588  N N     . ASP D 1 418 ? 101.154 104.538 198.210 1.00 54.69  ? 389 ASP B N     1 
ATOM   8589  C CA    . ASP D 1 418 ? 99.954  104.027 198.856 1.00 54.69  ? 389 ASP B CA    1 
ATOM   8590  C C     . ASP D 1 418 ? 98.704  104.443 198.085 1.00 54.69  ? 389 ASP B C     1 
ATOM   8591  O O     . ASP D 1 418 ? 98.718  105.381 197.286 1.00 54.69  ? 389 ASP B O     1 
ATOM   8592  C CB    . ASP D 1 418 ? 99.853  104.526 200.301 1.00 54.69  ? 389 ASP B CB    1 
ATOM   8593  C CG    . ASP D 1 418 ? 101.179 104.473 201.039 1.00 54.69  ? 389 ASP B CG    1 
ATOM   8594  O OD1   . ASP D 1 418 ? 102.068 103.708 200.611 1.00 54.69  ? 389 ASP B OD1   1 
ATOM   8595  O OD2   . ASP D 1 418 ? 101.330 105.196 202.046 1.00 54.69  ? 389 ASP B OD2   1 
ATOM   8596  N N     . GLU D 1 419 ? 97.605  103.730 198.345 1.00 54.85  ? 390 GLU B N     1 
ATOM   8597  C CA    . GLU D 1 419 ? 96.359  104.000 197.633 1.00 54.85  ? 390 GLU B CA    1 
ATOM   8598  C C     . GLU D 1 419 ? 95.776  105.349 198.040 1.00 54.85  ? 390 GLU B C     1 
ATOM   8599  O O     . GLU D 1 419 ? 95.351  106.136 197.187 1.00 54.85  ? 390 GLU B O     1 
ATOM   8600  C CB    . GLU D 1 419 ? 95.362  102.864 197.888 1.00 54.85  ? 390 GLU B CB    1 
ATOM   8601  C CG    . GLU D 1 419 ? 93.973  103.037 197.230 1.00 54.85  ? 390 GLU B CG    1 
ATOM   8602  C CD    . GLU D 1 419 ? 92.924  103.751 198.091 1.00 54.85  ? 390 GLU B CD    1 
ATOM   8603  O OE1   . GLU D 1 419 ? 93.026  103.743 199.336 1.00 54.85  ? 390 GLU B OE1   1 
ATOM   8604  O OE2   . GLU D 1 419 ? 91.986  104.330 197.504 1.00 54.85  ? 390 GLU B OE2   1 
ATOM   8605  N N     . GLU D 1 420 ? 95.734  105.632 199.344 1.00 53.82  ? 391 GLU B N     1 
ATOM   8606  C CA    . GLU D 1 420 ? 95.222  106.923 199.795 1.00 53.82  ? 391 GLU B CA    1 
ATOM   8607  C C     . GLU D 1 420 ? 96.137  108.060 199.361 1.00 53.82  ? 391 GLU B C     1 
ATOM   8608  O O     . GLU D 1 420 ? 95.668  109.177 199.102 1.00 53.82  ? 391 GLU B O     1 
ATOM   8609  C CB    . GLU D 1 420 ? 95.052  106.917 201.315 1.00 53.82  ? 391 GLU B CB    1 
ATOM   8610  C CG    . GLU D 1 420 ? 93.946  107.825 201.824 1.00 53.82  ? 391 GLU B CG    1 
ATOM   8611  C CD    . GLU D 1 420 ? 93.693  107.651 203.308 1.00 53.82  ? 391 GLU B CD    1 
ATOM   8612  O OE1   . GLU D 1 420 ? 94.575  107.101 204.001 1.00 53.82  ? 391 GLU B OE1   1 
ATOM   8613  O OE2   . GLU D 1 420 ? 92.611  108.059 203.781 1.00 53.82  ? 391 GLU B OE2   1 
ATOM   8614  N N     . CYS D 1 421 ? 97.440  107.790 199.262 1.00 52.18  ? 392 CYS B N     1 
ATOM   8615  C CA    . CYS D 1 421 ? 98.357  108.767 198.690 1.00 52.18  ? 392 CYS B CA    1 
ATOM   8616  C C     . CYS D 1 421 ? 98.020  109.045 197.231 1.00 52.18  ? 392 CYS B C     1 
ATOM   8617  O O     . CYS D 1 421 ? 98.075  110.198 196.783 1.00 52.18  ? 392 CYS B O     1 
ATOM   8618  C CB    . CYS D 1 421 ? 99.792  108.268 198.826 1.00 52.18  ? 392 CYS B CB    1 
ATOM   8619  S SG    . CYS D 1 421 ? 100.995 109.307 197.999 1.00 52.18  ? 392 CYS B SG    1 
ATOM   8620  N N     . LEU D 1 422 ? 97.670  108.002 196.472 1.00 46.13  ? 393 LEU B N     1 
ATOM   8621  C CA    . LEU D 1 422 ? 97.223  108.212 195.099 1.00 46.13  ? 393 LEU B CA    1 
ATOM   8622  C C     . LEU D 1 422 ? 95.935  109.021 195.063 1.00 46.13  ? 393 LEU B C     1 
ATOM   8623  O O     . LEU D 1 422 ? 95.744  109.842 194.163 1.00 46.13  ? 393 LEU B O     1 
ATOM   8624  C CB    . LEU D 1 422 ? 97.024  106.877 194.377 1.00 46.13  ? 393 LEU B CB    1 
ATOM   8625  C CG    . LEU D 1 422 ? 98.239  106.029 193.995 1.00 46.13  ? 393 LEU B CG    1 
ATOM   8626  C CD1   . LEU D 1 422 ? 97.779  104.712 193.386 1.00 46.13  ? 393 LEU B CD1   1 
ATOM   8627  C CD2   . LEU D 1 422 ? 99.167  106.758 193.039 1.00 46.13  ? 393 LEU B CD2   1 
ATOM   8628  N N     . VAL D 1 423 ? 95.039  108.801 196.033 1.00 47.53  ? 394 VAL B N     1 
ATOM   8629  C CA    . VAL D 1 423 ? 93.796  109.573 196.095 1.00 47.53  ? 394 VAL B CA    1 
ATOM   8630  C C     . VAL D 1 423 ? 94.098  111.051 196.319 1.00 47.53  ? 394 VAL B C     1 
ATOM   8631  O O     . VAL D 1 423 ? 93.501  111.925 195.677 1.00 47.53  ? 394 VAL B O     1 
ATOM   8632  C CB    . VAL D 1 423 ? 92.862  109.006 197.183 1.00 47.53  ? 394 VAL B CB    1 
ATOM   8633  C CG1   . VAL D 1 423 ? 91.681  109.951 197.449 1.00 47.53  ? 394 VAL B CG1   1 
ATOM   8634  C CG2   . VAL D 1 423 ? 92.336  107.637 196.763 1.00 47.53  ? 394 VAL B CG2   1 
ATOM   8635  N N     . LEU D 1 424 ? 95.031  111.351 197.224 1.00 47.17  ? 395 LEU B N     1 
ATOM   8636  C CA    . LEU D 1 424 ? 95.408  112.745 197.450 1.00 47.17  ? 395 LEU B CA    1 
ATOM   8637  C C     . LEU D 1 424 ? 96.065  113.350 196.214 1.00 47.17  ? 395 LEU B C     1 
ATOM   8638  O O     . LEU D 1 424 ? 95.799  114.508 195.864 1.00 47.17  ? 395 LEU B O     1 
ATOM   8639  C CB    . LEU D 1 424 ? 96.344  112.849 198.655 1.00 47.17  ? 395 LEU B CB    1 
ATOM   8640  C CG    . LEU D 1 424 ? 96.795  114.227 199.176 1.00 47.17  ? 395 LEU B CG    1 
ATOM   8641  C CD1   . LEU D 1 424 ? 95.769  115.353 199.002 1.00 47.17  ? 395 LEU B CD1   1 
ATOM   8642  C CD2   . LEU D 1 424 ? 97.202  114.109 200.633 1.00 47.17  ? 395 LEU B CD2   1 
ATOM   8643  N N     . LEU D 1 425 ? 96.924  112.581 195.538 1.00 43.10  ? 396 LEU B N     1 
ATOM   8644  C CA    . LEU D 1 425 ? 97.567  113.081 194.326 1.00 43.10  ? 396 LEU B CA    1 
ATOM   8645  C C     . LEU D 1 425 ? 96.547  113.335 193.223 1.00 43.10  ? 396 LEU B C     1 
ATOM   8646  O O     . LEU D 1 425 ? 96.654  114.317 192.483 1.00 43.10  ? 396 LEU B O     1 
ATOM   8647  C CB    . LEU D 1 425 ? 98.635  112.095 193.850 1.00 43.10  ? 396 LEU B CB    1 
ATOM   8648  C CG    . LEU D 1 425 ? 100.008 112.179 194.527 1.00 43.10  ? 396 LEU B CG    1 
ATOM   8649  C CD1   . LEU D 1 425 ? 100.843 110.955 194.188 1.00 43.10  ? 396 LEU B CD1   1 
ATOM   8650  C CD2   . LEU D 1 425 ? 100.758 113.451 194.134 1.00 43.10  ? 396 LEU B CD2   1 
ATOM   8651  N N     . GLY D 1 426 ? 95.546  112.464 193.100 1.00 41.69  ? 397 GLY B N     1 
ATOM   8652  C CA    . GLY D 1 426 ? 94.492  112.693 192.127 1.00 41.69  ? 397 GLY B CA    1 
ATOM   8653  C C     . GLY D 1 426 ? 93.645  113.904 192.463 1.00 41.69  ? 397 GLY B C     1 
ATOM   8654  O O     . GLY D 1 426 ? 93.198  114.625 191.567 1.00 41.69  ? 397 GLY B O     1 
ATOM   8655  N N     . GLU D 1 427 ? 93.397  114.133 193.756 1.00 44.33  ? 398 GLU B N     1 
ATOM   8656  C CA    . GLU D 1 427 ? 92.677  115.335 194.165 1.00 44.33  ? 398 GLU B CA    1 
ATOM   8657  C C     . GLU D 1 427 ? 93.473  116.580 193.791 1.00 44.33  ? 398 GLU B C     1 
ATOM   8658  O O     . GLU D 1 427 ? 92.906  117.568 193.310 1.00 44.33  ? 398 GLU B O     1 
ATOM   8659  C CB    . GLU D 1 427 ? 92.393  115.273 195.673 1.00 44.33  ? 398 GLU B CB    1 
ATOM   8660  C CG    . GLU D 1 427 ? 91.399  116.308 196.266 1.00 44.33  ? 398 GLU B CG    1 
ATOM   8661  C CD    . GLU D 1 427 ? 91.948  117.720 196.409 1.00 44.33  ? 398 GLU B CD    1 
ATOM   8662  O OE1   . GLU D 1 427 ? 91.275  118.666 195.952 1.00 44.33  ? 398 GLU B OE1   1 
ATOM   8663  O OE2   . GLU D 1 427 ? 93.057  117.877 196.961 1.00 44.33  ? 398 GLU B OE2   1 
ATOM   8664  N N     . ILE D 1 428 ? 94.792  116.542 193.994 1.00 42.59  ? 399 ILE B N     1 
ATOM   8665  C CA    . ILE D 1 428 ? 95.636  117.668 193.598 1.00 42.59  ? 399 ILE B CA    1 
ATOM   8666  C C     . ILE D 1 428 ? 95.625  117.827 192.080 1.00 42.59  ? 399 ILE B C     1 
ATOM   8667  O O     . ILE D 1 428 ? 95.664  118.949 191.561 1.00 42.59  ? 399 ILE B O     1 
ATOM   8668  C CB    . ILE D 1 428 ? 97.068  117.489 194.145 1.00 42.59  ? 399 ILE B CB    1 
ATOM   8669  C CG1   . ILE D 1 428 ? 97.097  117.655 195.670 1.00 42.59  ? 399 ILE B CG1   1 
ATOM   8670  C CG2   . ILE D 1 428 ? 98.034  118.504 193.514 1.00 42.59  ? 399 ILE B CG2   1 
ATOM   8671  C CD1   . ILE D 1 428 ? 98.249  116.935 196.344 1.00 42.59  ? 399 ILE B CD1   1 
ATOM   8672  N N     . GLY D 1 429 ? 95.585  116.712 191.349 1.00 40.63  ? 400 GLY B N     1 
ATOM   8673  C CA    . GLY D 1 429 ? 95.570  116.787 189.897 1.00 40.63  ? 400 GLY B CA    1 
ATOM   8674  C C     . GLY D 1 429 ? 94.302  117.422 189.359 1.00 40.63  ? 400 GLY B C     1 
ATOM   8675  O O     . GLY D 1 429 ? 94.349  118.273 188.467 1.00 40.63  ? 400 GLY B O     1 
ATOM   8676  N N     . GLN D 1 430 ? 93.150  117.017 189.895 1.00 42.24  ? 401 GLN B N     1 
ATOM   8677  C CA    . GLN D 1 430 ? 91.902  117.668 189.513 1.00 42.24  ? 401 GLN B CA    1 
ATOM   8678  C C     . GLN D 1 430 ? 91.856  119.116 189.982 1.00 42.24  ? 401 GLN B C     1 
ATOM   8679  O O     . GLN D 1 430 ? 91.215  119.952 189.335 1.00 42.24  ? 401 GLN B O     1 
ATOM   8680  C CB    . GLN D 1 430 ? 90.700  116.907 190.073 1.00 42.24  ? 401 GLN B CB    1 
ATOM   8681  C CG    . GLN D 1 430 ? 90.583  115.460 189.575 1.00 42.24  ? 401 GLN B CG    1 
ATOM   8682  C CD    . GLN D 1 430 ? 89.315  114.720 190.021 1.00 42.24  ? 401 GLN B CD    1 
ATOM   8683  O OE1   . GLN D 1 430 ? 89.374  113.523 190.295 1.00 42.24  ? 401 GLN B OE1   1 
ATOM   8684  N NE2   . GLN D 1 430 ? 88.168  115.400 190.042 1.00 42.24  ? 401 GLN B NE2   1 
ATOM   8685  N N     . ARG D 1 431 ? 92.512  119.432 191.101 1.00 44.65  ? 402 ARG B N     1 
ATOM   8686  C CA    . ARG D 1 431 ? 92.440  120.788 191.634 1.00 44.65  ? 402 ARG B CA    1 
ATOM   8687  C C     . ARG D 1 431 ? 93.164  121.781 190.733 1.00 44.65  ? 402 ARG B C     1 
ATOM   8688  O O     . ARG D 1 431 ? 92.605  122.829 190.386 1.00 44.65  ? 402 ARG B O     1 
ATOM   8689  C CB    . ARG D 1 431 ? 93.021  120.827 193.047 1.00 44.65  ? 402 ARG B CB    1 
ATOM   8690  C CG    . ARG D 1 431 ? 92.832  122.166 193.743 1.00 44.65  ? 402 ARG B CG    1 
ATOM   8691  C CD    . ARG D 1 431 ? 92.855  122.024 195.257 1.00 44.65  ? 402 ARG B CD    1 
ATOM   8692  N NE    . ARG D 1 431 ? 94.124  121.493 195.745 1.00 44.65  ? 402 ARG B NE    1 
ATOM   8693  C CZ    . ARG D 1 431 ? 95.277  122.152 195.776 1.00 44.65  ? 402 ARG B CZ    1 
ATOM   8694  N NH1   . ARG D 1 431 ? 95.385  123.404 195.350 1.00 44.65  ? 402 ARG B NH1   1 
ATOM   8695  N NH2   . ARG D 1 431 ? 96.357  121.541 196.253 1.00 44.65  ? 402 ARG B NH2   1 
ATOM   8696  N N     . THR D 1 432 ? 94.400  121.462 190.333 1.00 42.05  ? 403 THR B N     1 
ATOM   8697  C CA    . THR D 1 432 ? 95.266  122.376 189.593 1.00 42.05  ? 403 THR B CA    1 
ATOM   8698  C C     . THR D 1 432 ? 95.521  121.907 188.166 1.00 42.05  ? 403 THR B C     1 
ATOM   8699  O O     . THR D 1 432 ? 95.145  122.600 187.217 1.00 42.05  ? 403 THR B O     1 
ATOM   8700  C CB    . THR D 1 432 ? 96.601  122.532 190.334 1.00 42.05  ? 403 THR B CB    1 
ATOM   8701  O OG1   . THR D 1 432 ? 97.260  121.262 190.409 1.00 42.05  ? 403 THR B OG1   1 
ATOM   8702  C CG2   . THR D 1 432 ? 96.381  123.069 191.740 1.00 42.05  ? 403 THR B CG2   1 
ATOM   8703  N N     . SER D 1 433 ? 96.129  120.735 187.992 1.00 39.33  ? 404 SER B N     1 
ATOM   8704  C CA    . SER D 1 433 ? 96.403  120.163 186.678 1.00 39.33  ? 404 SER B CA    1 
ATOM   8705  C C     . SER D 1 433 ? 97.086  118.820 186.878 1.00 39.33  ? 404 SER B C     1 
ATOM   8706  O O     . SER D 1 433 ? 97.712  118.573 187.912 1.00 39.33  ? 404 SER B O     1 
ATOM   8707  C CB    . SER D 1 433 ? 97.289  121.071 185.818 1.00 39.33  ? 404 SER B CB    1 
ATOM   8708  O OG    . SER D 1 433 ? 96.542  122.147 185.278 1.00 39.33  ? 404 SER B OG    1 
ATOM   8709  N N     . LEU D 1 434 ? 96.990  117.969 185.857 1.00 33.64  ? 405 LEU B N     1 
ATOM   8710  C CA    . LEU D 1 434 ? 97.632  116.661 185.925 1.00 33.64  ? 405 LEU B CA    1 
ATOM   8711  C C     . LEU D 1 434 ? 99.150  116.772 185.845 1.00 33.64  ? 405 LEU B C     1 
ATOM   8712  O O     . LEU D 1 434 ? 99.861  115.947 186.435 1.00 33.64  ? 405 LEU B O     1 
ATOM   8713  C CB    . LEU D 1 434 ? 97.102  115.773 184.799 1.00 33.64  ? 405 LEU B CB    1 
ATOM   8714  C CG    . LEU D 1 434 ? 97.632  114.346 184.651 1.00 33.64  ? 405 LEU B CG    1 
ATOM   8715  C CD1   . LEU D 1 434 ? 97.615  113.570 185.956 1.00 33.64  ? 405 LEU B CD1   1 
ATOM   8716  C CD2   . LEU D 1 434 ? 96.814  113.630 183.598 1.00 33.64  ? 405 LEU B CD2   1 
ATOM   8717  N N     . ARG D 1 435 ? 99.657  117.773 185.117 1.00 33.43  ? 406 ARG B N     1 
ATOM   8718  C CA    . ARG D 1 435 ? 101.101 117.945 184.974 1.00 33.43  ? 406 ARG B CA    1 
ATOM   8719  C C     . ARG D 1 435 ? 101.760 118.239 186.317 1.00 33.43  ? 406 ARG B C     1 
ATOM   8720  O O     . ARG D 1 435 ? 102.810 117.670 186.642 1.00 33.43  ? 406 ARG B O     1 
ATOM   8721  C CB    . ARG D 1 435 ? 101.391 119.060 183.973 1.00 33.43  ? 406 ARG B CB    1 
ATOM   8722  C CG    . ARG D 1 435 ? 101.361 118.586 182.532 1.00 33.43  ? 406 ARG B CG    1 
ATOM   8723  C CD    . ARG D 1 435 ? 101.514 119.735 181.567 1.00 33.43  ? 406 ARG B CD    1 
ATOM   8724  N NE    . ARG D 1 435 ? 102.107 119.320 180.300 1.00 33.43  ? 406 ARG B NE    1 
ATOM   8725  C CZ    . ARG D 1 435 ? 102.330 120.114 179.258 1.00 33.43  ? 406 ARG B CZ    1 
ATOM   8726  N NH1   . ARG D 1 435 ? 101.978 121.394 179.259 1.00 33.43  ? 406 ARG B NH1   1 
ATOM   8727  N NH2   . ARG D 1 435 ? 102.916 119.610 178.176 1.00 33.43  ? 406 ARG B NH2   1 
ATOM   8728  N N     . HIS D 1 436 ? 101.141 119.107 187.121 1.00 38.44  ? 407 HIS B N     1 
ATOM   8729  C CA    . HIS D 1 436 ? 101.653 119.379 188.460 1.00 38.44  ? 407 HIS B CA    1 
ATOM   8730  C C     . HIS D 1 436 ? 101.609 118.131 189.332 1.00 38.44  ? 407 HIS B C     1 
ATOM   8731  O O     . HIS D 1 436 ? 102.550 117.861 190.091 1.00 38.44  ? 407 HIS B O     1 
ATOM   8732  C CB    . HIS D 1 436 ? 100.845 120.507 189.102 1.00 38.44  ? 407 HIS B CB    1 
ATOM   8733  C CG    . HIS D 1 436 ? 101.331 120.901 190.460 1.00 38.44  ? 407 HIS B CG    1 
ATOM   8734  N ND1   . HIS D 1 436 ? 102.580 121.441 190.676 1.00 38.44  ? 407 HIS B ND1   1 
ATOM   8735  C CD2   . HIS D 1 436 ? 100.735 120.835 191.674 1.00 38.44  ? 407 HIS B CD2   1 
ATOM   8736  C CE1   . HIS D 1 436 ? 102.733 121.689 191.964 1.00 38.44  ? 407 HIS B CE1   1 
ATOM   8737  N NE2   . HIS D 1 436 ? 101.628 121.331 192.592 1.00 38.44  ? 407 HIS B NE2   1 
ATOM   8738  N N     . ALA D 1 437 ? 100.528 117.354 189.227 1.00 36.95  ? 408 ALA B N     1 
ATOM   8739  C CA    . ALA D 1 437 ? 100.379 116.163 190.055 1.00 36.95  ? 408 ALA B CA    1 
ATOM   8740  C C     . ALA D 1 437 ? 101.446 115.124 189.740 1.00 36.95  ? 408 ALA B C     1 
ATOM   8741  O O     . ALA D 1 437 ? 102.002 114.506 190.655 1.00 36.95  ? 408 ALA B O     1 
ATOM   8742  C CB    . ALA D 1 437 ? 98.987  115.567 189.867 1.00 36.95  ? 408 ALA B CB    1 
ATOM   8743  N N     . VAL D 1 438 ? 101.748 114.912 188.457 1.00 36.36  ? 409 VAL B N     1 
ATOM   8744  C CA    . VAL D 1 438 ? 102.818 113.973 188.121 1.00 36.36  ? 409 VAL B CA    1 
ATOM   8745  C C     . VAL D 1 438 ? 104.176 114.541 188.526 1.00 36.36  ? 409 VAL B C     1 
ATOM   8746  O O     . VAL D 1 438 ? 105.055 113.797 188.976 1.00 36.36  ? 409 VAL B O     1 
ATOM   8747  C CB    . VAL D 1 438 ? 102.776 113.568 186.630 1.00 36.36  ? 409 VAL B CB    1 
ATOM   8748  C CG1   . VAL D 1 438 ? 102.977 114.740 185.687 1.00 36.36  ? 409 VAL B CG1   1 
ATOM   8749  C CG2   . VAL D 1 438 ? 103.810 112.483 186.333 1.00 36.36  ? 409 VAL B CG2   1 
ATOM   8750  N N     . GLN D 1 439 ? 104.381 115.857 188.376 1.00 40.24  ? 410 GLN B N     1 
ATOM   8751  C CA    . GLN D 1 439 ? 105.693 116.409 188.707 1.00 40.24  ? 410 GLN B CA    1 
ATOM   8752  C C     . GLN D 1 439 ? 105.959 116.408 190.208 1.00 40.24  ? 410 GLN B C     1 
ATOM   8753  O O     . GLN D 1 439 ? 107.125 116.455 190.608 1.00 40.24  ? 410 GLN B O     1 
ATOM   8754  C CB    . GLN D 1 439 ? 105.851 117.827 188.127 1.00 40.24  ? 410 GLN B CB    1 
ATOM   8755  C CG    . GLN D 1 439 ? 105.682 119.018 189.084 1.00 40.24  ? 410 GLN B CG    1 
ATOM   8756  C CD    . GLN D 1 439 ? 105.682 120.336 188.346 1.00 40.24  ? 410 GLN B CD    1 
ATOM   8757  O OE1   . GLN D 1 439 ? 106.104 120.409 187.197 1.00 40.24  ? 410 GLN B OE1   1 
ATOM   8758  N NE2   . GLN D 1 439 ? 105.228 121.390 189.012 1.00 40.24  ? 410 GLN B NE2   1 
ATOM   8759  N N     . LEU D 1 440 ? 104.918 116.369 191.046 1.00 40.51  ? 411 LEU B N     1 
ATOM   8760  C CA    . LEU D 1 440 ? 105.140 116.299 192.490 1.00 40.51  ? 411 LEU B CA    1 
ATOM   8761  C C     . LEU D 1 440 ? 105.684 114.951 192.964 1.00 40.51  ? 411 LEU B C     1 
ATOM   8762  O O     . LEU D 1 440 ? 106.083 114.854 194.129 1.00 40.51  ? 411 LEU B O     1 
ATOM   8763  C CB    . LEU D 1 440 ? 103.841 116.592 193.254 1.00 40.51  ? 411 LEU B CB    1 
ATOM   8764  C CG    . LEU D 1 440 ? 103.261 118.008 193.387 1.00 40.51  ? 411 LEU B CG    1 
ATOM   8765  C CD1   . LEU D 1 440 ? 102.131 117.983 194.401 1.00 40.51  ? 411 LEU B CD1   1 
ATOM   8766  C CD2   . LEU D 1 440 ? 104.288 119.061 193.779 1.00 40.51  ? 411 LEU B CD2   1 
ATOM   8767  N N     . LEU D 1 441 ? 105.706 113.917 192.116 1.00 40.49  ? 412 LEU B N     1 
ATOM   8768  C CA    . LEU D 1 441 ? 106.071 112.580 192.583 1.00 40.49  ? 412 LEU B CA    1 
ATOM   8769  C C     . LEU D 1 441 ? 107.540 112.496 192.986 1.00 40.49  ? 412 LEU B C     1 
ATOM   8770  O O     . LEU D 1 441 ? 107.872 111.861 193.993 1.00 40.49  ? 412 LEU B O     1 
ATOM   8771  C CB    . LEU D 1 441 ? 105.761 111.547 191.502 1.00 40.49  ? 412 LEU B CB    1 
ATOM   8772  C CG    . LEU D 1 441 ? 104.286 111.179 191.322 1.00 40.49  ? 412 LEU B CG    1 
ATOM   8773  C CD1   . LEU D 1 441 ? 104.078 110.463 189.995 1.00 40.49  ? 412 LEU B CD1   1 
ATOM   8774  C CD2   . LEU D 1 441 ? 103.778 110.322 192.479 1.00 40.49  ? 412 LEU B CD2   1 
ATOM   8775  N N     . SER D 1 442 ? 108.433 113.098 192.202 1.00 43.70  ? 413 SER B N     1 
ATOM   8776  C CA    . SER D 1 442 ? 109.853 113.085 192.553 1.00 43.70  ? 413 SER B CA    1 
ATOM   8777  C C     . SER D 1 442 ? 110.150 113.800 193.867 1.00 43.70  ? 413 SER B C     1 
ATOM   8778  O O     . SER D 1 442 ? 110.847 113.212 194.714 1.00 43.70  ? 413 SER B O     1 
ATOM   8779  C CB    . SER D 1 442 ? 110.674 113.676 191.403 1.00 43.70  ? 413 SER B CB    1 
ATOM   8780  O OG    . SER D 1 442 ? 110.883 112.716 190.384 1.00 43.70  ? 413 SER B OG    1 
ATOM   8781  N N     . PRO D 1 443 ? 109.691 115.038 194.108 1.00 42.94  ? 414 PRO B N     1 
ATOM   8782  C CA    . PRO D 1 443 ? 109.882 115.617 195.448 1.00 42.94  ? 414 PRO B CA    1 
ATOM   8783  C C     . PRO D 1 443 ? 109.175 114.844 196.544 1.00 42.94  ? 414 PRO B C     1 
ATOM   8784  O O     . PRO D 1 443 ? 109.656 114.837 197.681 1.00 42.94  ? 414 PRO B O     1 
ATOM   8785  C CB    . PRO D 1 443 ? 109.328 117.043 195.314 1.00 42.94  ? 414 PRO B CB    1 
ATOM   8786  C CG    . PRO D 1 443 ? 108.604 117.085 194.042 1.00 42.94  ? 414 PRO B CG    1 
ATOM   8787  C CD    . PRO D 1 443 ? 109.188 116.047 193.160 1.00 42.94  ? 414 PRO B CD    1 
ATOM   8788  N N     . ALA D 1 444 ? 108.057 114.181 196.238 1.00 46.38  ? 415 ALA B N     1 
ATOM   8789  C CA    . ALA D 1 444 ? 107.438 113.299 197.222 1.00 46.38  ? 415 ALA B CA    1 
ATOM   8790  C C     . ALA D 1 444 ? 108.362 112.142 197.572 1.00 46.38  ? 415 ALA B C     1 
ATOM   8791  O O     . ALA D 1 444 ? 108.493 111.777 198.746 1.00 46.38  ? 415 ALA B O     1 
ATOM   8792  C CB    . ALA D 1 444 ? 106.098 112.783 196.702 1.00 46.38  ? 415 ALA B CB    1 
ATOM   8793  N N     . SER D 1 445 ? 109.030 111.568 196.569 1.00 47.71  ? 416 SER B N     1 
ATOM   8794  C CA    . SER D 1 445 ? 109.979 110.492 196.835 1.00 47.71  ? 416 SER B CA    1 
ATOM   8795  C C     . SER D 1 445 ? 111.167 110.988 197.649 1.00 47.71  ? 416 SER B C     1 
ATOM   8796  O O     . SER D 1 445 ? 111.651 110.280 198.537 1.00 47.71  ? 416 SER B O     1 
ATOM   8797  C CB    . SER D 1 445 ? 110.456 109.877 195.523 1.00 47.71  ? 416 SER B CB    1 
ATOM   8798  O OG    . SER D 1 445 ? 111.350 108.805 195.765 1.00 47.71  ? 416 SER B OG    1 
ATOM   8799  N N     . ILE D 1 446 ? 111.655 112.196 197.358 1.00 47.81  ? 417 ILE B N     1 
ATOM   8800  C CA    . ILE D 1 446 ? 112.796 112.723 198.105 1.00 47.81  ? 417 ILE B CA    1 
ATOM   8801  C C     . ILE D 1 446 ? 112.397 113.034 199.544 1.00 47.81  ? 417 ILE B C     1 
ATOM   8802  O O     . ILE D 1 446 ? 113.178 112.813 200.476 1.00 47.81  ? 417 ILE B O     1 
ATOM   8803  C CB    . ILE D 1 446 ? 113.382 113.960 197.394 1.00 47.81  ? 417 ILE B CB    1 
ATOM   8804  C CG1   . ILE D 1 446 ? 113.961 113.604 196.007 1.00 47.81  ? 417 ILE B CG1   1 
ATOM   8805  C CG2   . ILE D 1 446 ? 114.436 114.652 198.270 1.00 47.81  ? 417 ILE B CG2   1 
ATOM   8806  C CD1   . ILE D 1 446 ? 115.146 112.621 195.982 1.00 47.81  ? 417 ILE B CD1   1 
ATOM   8807  N N     . VAL D 1 447 ? 111.189 113.562 199.750 1.00 49.35  ? 418 VAL B N     1 
ATOM   8808  C CA    . VAL D 1 447 ? 110.726 113.841 201.105 1.00 49.35  ? 418 VAL B CA    1 
ATOM   8809  C C     . VAL D 1 447 ? 110.508 112.540 201.867 1.00 49.35  ? 418 VAL B C     1 
ATOM   8810  O O     . VAL D 1 447 ? 110.756 112.467 203.076 1.00 49.35  ? 418 VAL B O     1 
ATOM   8811  C CB    . VAL D 1 447 ? 109.453 114.710 201.060 1.00 49.35  ? 418 VAL B CB    1 
ATOM   8812  C CG1   . VAL D 1 447 ? 108.713 114.719 202.411 1.00 49.35  ? 418 VAL B CG1   1 
ATOM   8813  C CG2   . VAL D 1 447 ? 109.811 116.134 200.650 1.00 49.35  ? 418 VAL B CG2   1 
ATOM   8814  N N     . ALA D 1 448 ? 110.030 111.498 201.183 1.00 53.19  ? 419 ALA B N     1 
ATOM   8815  C CA    . ALA D 1 448 ? 109.864 110.205 201.839 1.00 53.19  ? 419 ALA B CA    1 
ATOM   8816  C C     . ALA D 1 448 ? 111.211 109.587 202.186 1.00 53.19  ? 419 ALA B C     1 
ATOM   8817  O O     . ALA D 1 448 ? 111.347 108.937 203.229 1.00 53.19  ? 419 ALA B O     1 
ATOM   8818  C CB    . ALA D 1 448 ? 109.057 109.264 200.947 1.00 53.19  ? 419 ALA B CB    1 
ATOM   8819  N N     . LYS D 1 449 ? 112.212 109.767 201.318 1.00 54.17  ? 420 LYS B N     1 
ATOM   8820  C CA    . LYS D 1 449 ? 113.546 109.243 201.595 1.00 54.17  ? 420 LYS B CA    1 
ATOM   8821  C C     . LYS D 1 449 ? 114.142 109.900 202.832 1.00 54.17  ? 420 LYS B C     1 
ATOM   8822  O O     . LYS D 1 449 ? 114.772 109.230 203.659 1.00 54.17  ? 420 LYS B O     1 
ATOM   8823  C CB    . LYS D 1 449 ? 114.453 109.453 200.384 1.00 54.17  ? 420 LYS B CB    1 
ATOM   8824  C CG    . LYS D 1 449 ? 115.825 108.798 200.512 1.00 54.17  ? 420 LYS B CG    1 
ATOM   8825  C CD    . LYS D 1 449 ? 116.934 109.816 200.751 1.00 54.17  ? 420 LYS B CD    1 
ATOM   8826  C CE    . LYS D 1 449 ? 118.302 109.151 200.732 1.00 54.17  ? 420 LYS B CE    1 
ATOM   8827  N NZ    . LYS D 1 449 ? 119.410 110.142 200.797 1.00 54.17  ? 420 LYS B NZ    1 
ATOM   8828  N N     . MET D 1 450 ? 113.960 111.210 202.973 1.00 57.97  ? 421 MET B N     1 
ATOM   8829  C CA    . MET D 1 450 ? 114.184 111.844 204.262 1.00 57.97  ? 421 MET B CA    1 
ATOM   8830  C C     . MET D 1 450 ? 113.189 111.278 205.265 1.00 57.97  ? 421 MET B C     1 
ATOM   8831  O O     . MET D 1 450 ? 112.056 110.943 204.910 1.00 57.97  ? 421 MET B O     1 
ATOM   8832  C CB    . MET D 1 450 ? 114.035 113.361 204.147 1.00 57.97  ? 421 MET B CB    1 
ATOM   8833  C CG    . MET D 1 450 ? 115.275 114.045 203.566 1.00 57.97  ? 421 MET B CG    1 
ATOM   8834  S SD    . MET D 1 450 ? 115.222 115.835 203.255 1.00 57.97  ? 421 MET B SD    1 
ATOM   8835  C CE    . MET D 1 450 ? 113.525 116.304 203.599 1.00 57.97  ? 421 MET B CE    1 
ATOM   8836  N N     . ASN D 1 451 ? 113.628 111.154 206.518 1.00 64.73  ? 422 ASN B N     1 
ATOM   8837  C CA    . ASN D 1 451 ? 112.956 110.430 207.600 1.00 64.73  ? 422 ASN B CA    1 
ATOM   8838  C C     . ASN D 1 451 ? 112.958 108.915 207.402 1.00 64.73  ? 422 ASN B C     1 
ATOM   8839  O O     . ASN D 1 451 ? 112.251 108.209 208.134 1.00 64.73  ? 422 ASN B O     1 
ATOM   8840  C CB    . ASN D 1 451 ? 111.509 110.897 207.821 1.00 64.73  ? 422 ASN B CB    1 
ATOM   8841  C CG    . ASN D 1 451 ? 111.366 112.407 207.782 1.00 64.73  ? 422 ASN B CG    1 
ATOM   8842  O OD1   . ASN D 1 451 ? 111.740 113.102 208.726 1.00 64.73  ? 422 ASN B OD1   1 
ATOM   8843  N ND2   . ASN D 1 451 ? 110.822 112.923 206.684 1.00 64.73  ? 422 ASN B ND2   1 
ATOM   8844  N N     . GLY D 1 452 ? 113.723 108.388 206.441 1.00 64.48  ? 423 GLY B N     1 
ATOM   8845  C CA    . GLY D 1 452 ? 113.978 106.962 206.356 1.00 64.48  ? 423 GLY B CA    1 
ATOM   8846  C C     . GLY D 1 452 ? 112.784 106.069 206.083 1.00 64.48  ? 423 GLY B C     1 
ATOM   8847  O O     . GLY D 1 452 ? 112.600 105.070 206.785 1.00 64.48  ? 423 GLY B O     1 
ATOM   8848  N N     . ARG D 1 453 ? 111.962 106.420 205.091 1.00 63.84  ? 424 ARG B N     1 
ATOM   8849  C CA    . ARG D 1 453 ? 110.846 105.590 204.642 1.00 63.84  ? 424 ARG B CA    1 
ATOM   8850  C C     . ARG D 1 453 ? 110.941 105.419 203.134 1.00 63.84  ? 424 ARG B C     1 
ATOM   8851  O O     . ARG D 1 453 ? 110.929 106.405 202.392 1.00 63.84  ? 424 ARG B O     1 
ATOM   8852  C CB    . ARG D 1 453 ? 109.500 106.212 205.027 1.00 63.84  ? 424 ARG B CB    1 
ATOM   8853  C CG    . ARG D 1 453 ? 108.321 105.254 204.906 1.00 63.84  ? 424 ARG B CG    1 
ATOM   8854  C CD    . ARG D 1 453 ? 106.991 105.951 205.144 1.00 63.84  ? 424 ARG B CD    1 
ATOM   8855  N NE    . ARG D 1 453 ? 106.865 106.447 206.512 1.00 63.84  ? 424 ARG B NE    1 
ATOM   8856  C CZ    . ARG D 1 453 ? 105.725 106.738 207.132 1.00 63.84  ? 424 ARG B CZ    1 
ATOM   8857  N NH1   . ARG D 1 453 ? 104.546 106.610 206.538 1.00 63.84  ? 424 ARG B NH1   1 
ATOM   8858  N NH2   . ARG D 1 453 ? 105.767 107.173 208.388 1.00 63.84  ? 424 ARG B NH2   1 
ATOM   8859  N N     . ASP D 1 454 ? 111.023 104.166 202.681 1.00 69.25  ? 425 ASP B N     1 
ATOM   8860  C CA    . ASP D 1 454 ? 111.079 103.906 201.247 1.00 69.25  ? 425 ASP B CA    1 
ATOM   8861  C C     . ASP D 1 454 ? 109.735 104.156 200.575 1.00 69.25  ? 425 ASP B C     1 
ATOM   8862  O O     . ASP D 1 454 ? 109.697 104.604 199.423 1.00 69.25  ? 425 ASP B O     1 
ATOM   8863  C CB    . ASP D 1 454 ? 111.535 102.469 200.993 1.00 69.25  ? 425 ASP B CB    1 
ATOM   8864  C CG    . ASP D 1 454 ? 112.946 102.205 201.488 1.00 69.25  ? 425 ASP B CG    1 
ATOM   8865  O OD1   . ASP D 1 454 ? 113.661 103.177 201.812 1.00 69.25  ? 425 ASP B OD1   1 
ATOM   8866  O OD2   . ASP D 1 454 ? 113.341 101.022 201.550 1.00 69.25  ? 425 ASP B OD2   1 
ATOM   8867  N N     . ASN D 1 455 ? 108.632 103.883 201.271 1.00 62.67  ? 426 ASN B N     1 
ATOM   8868  C CA    . ASN D 1 455 ? 107.294 104.048 200.719 1.00 62.67  ? 426 ASN B CA    1 
ATOM   8869  C C     . ASN D 1 455 ? 106.805 105.470 200.959 1.00 62.67  ? 426 ASN B C     1 
ATOM   8870  O O     . ASN D 1 455 ? 106.939 106.002 202.066 1.00 62.67  ? 426 ASN B O     1 
ATOM   8871  C CB    . ASN D 1 455 ? 106.324 103.046 201.347 1.00 62.67  ? 426 ASN B CB    1 
ATOM   8872  C CG    . ASN D 1 455 ? 106.911 101.649 201.446 1.00 62.67  ? 426 ASN B CG    1 
ATOM   8873  O OD1   . ASN D 1 455 ? 107.889 101.426 202.159 1.00 62.67  ? 426 ASN B OD1   1 
ATOM   8874  N ND2   . ASN D 1 455 ? 106.317 100.700 200.729 1.00 62.67  ? 426 ASN B ND2   1 
ATOM   8875  N N     . ILE D 1 456 ? 106.242 106.078 199.921 1.00 52.02  ? 427 ILE B N     1 
ATOM   8876  C CA    . ILE D 1 456 ? 105.710 107.433 200.014 1.00 52.02  ? 427 ILE B CA    1 
ATOM   8877  C C     . ILE D 1 456 ? 104.363 107.379 200.723 1.00 52.02  ? 427 ILE B C     1 
ATOM   8878  O O     . ILE D 1 456 ? 103.537 106.500 200.447 1.00 52.02  ? 427 ILE B O     1 
ATOM   8879  C CB    . ILE D 1 456 ? 105.592 108.067 198.613 1.00 52.02  ? 427 ILE B CB    1 
ATOM   8880  C CG1   . ILE D 1 456 ? 106.980 108.314 197.998 1.00 52.02  ? 427 ILE B CG1   1 
ATOM   8881  C CG2   . ILE D 1 456 ? 104.832 109.389 198.683 1.00 52.02  ? 427 ILE B CG2   1 
ATOM   8882  C CD1   . ILE D 1 456 ? 106.980 108.430 196.480 1.00 52.02  ? 427 ILE B CD1   1 
ATOM   8883  N N     . CYS D 1 457 ? 104.140 108.325 201.637 1.00 54.00  ? 428 CYS B N     1 
ATOM   8884  C CA    . CYS D 1 457 ? 102.961 108.385 202.493 1.00 54.00  ? 428 CYS B CA    1 
ATOM   8885  C C     . CYS D 1 457 ? 102.162 109.654 202.215 1.00 54.00  ? 428 CYS B C     1 
ATOM   8886  O O     . CYS D 1 457 ? 102.586 110.537 201.466 1.00 54.00  ? 428 CYS B O     1 
ATOM   8887  C CB    . CYS D 1 457 ? 103.360 108.326 203.972 1.00 54.00  ? 428 CYS B CB    1 
ATOM   8888  S SG    . CYS D 1 457 ? 103.734 109.931 204.703 1.00 54.00  ? 428 CYS B SG    1 
ATOM   8889  N N     . LYS D 1 458 ? 100.984 109.728 202.840 1.00 50.73  ? 429 LYS B N     1 
ATOM   8890  C CA    . LYS D 1 458 ? 100.079 110.853 202.618 1.00 50.73  ? 429 LYS B CA    1 
ATOM   8891  C C     . LYS D 1 458 ? 100.653 112.152 203.174 1.00 50.73  ? 429 LYS B C     1 
ATOM   8892  O O     . LYS D 1 458 ? 100.487 113.221 202.570 1.00 50.73  ? 429 LYS B O     1 
ATOM   8893  C CB    . LYS D 1 458 ? 98.720  110.547 203.251 1.00 50.73  ? 429 LYS B CB    1 
ATOM   8894  C CG    . LYS D 1 458 ? 97.588  111.481 202.837 1.00 50.73  ? 429 LYS B CG    1 
ATOM   8895  C CD    . LYS D 1 458 ? 96.335  111.219 203.658 1.00 50.73  ? 429 LYS B CD    1 
ATOM   8896  C CE    . LYS D 1 458 ? 95.249  112.239 203.364 1.00 50.73  ? 429 LYS B CE    1 
ATOM   8897  N NZ    . LYS D 1 458 ? 94.115  112.129 204.321 1.00 50.73  ? 429 LYS B NZ    1 
ATOM   8898  N N     . ALA D 1 459 ? 101.315 112.083 204.332 1.00 50.05  ? 430 ALA B N     1 
ATOM   8899  C CA    . ALA D 1 459 ? 101.891 113.285 204.927 1.00 50.05  ? 430 ALA B CA    1 
ATOM   8900  C C     . ALA D 1 459 ? 103.001 113.864 204.060 1.00 50.05  ? 430 ALA B C     1 
ATOM   8901  O O     . ALA D 1 459 ? 103.229 115.078 204.080 1.00 50.05  ? 430 ALA B O     1 
ATOM   8902  C CB    . ALA D 1 459 ? 102.419 112.981 206.329 1.00 50.05  ? 430 ALA B CB    1 
ATOM   8903  N N     . ASP D 1 460 ? 103.690 113.020 203.285 1.00 50.83  ? 431 ASP B N     1 
ATOM   8904  C CA    . ASP D 1 460 ? 104.688 113.525 202.348 1.00 50.83  ? 431 ASP B CA    1 
ATOM   8905  C C     . ASP D 1 460 ? 104.047 114.416 201.291 1.00 50.83  ? 431 ASP B C     1 
ATOM   8906  O O     . ASP D 1 460 ? 104.587 115.476 200.957 1.00 50.83  ? 431 ASP B O     1 
ATOM   8907  C CB    . ASP D 1 460 ? 105.431 112.361 201.693 1.00 50.83  ? 431 ASP B CB    1 
ATOM   8908  C CG    . ASP D 1 460 ? 106.122 111.468 202.705 1.00 50.83  ? 431 ASP B CG    1 
ATOM   8909  O OD1   . ASP D 1 460 ? 106.534 111.980 203.767 1.00 50.83  ? 431 ASP B OD1   1 
ATOM   8910  O OD2   . ASP D 1 460 ? 106.254 110.256 202.440 1.00 50.83  ? 431 ASP B OD2   1 
ATOM   8911  N N     . ILE D 1 461 ? 102.874 114.028 200.785 1.00 46.70  ? 432 ILE B N     1 
ATOM   8912  C CA    . ILE D 1 461 ? 102.193 114.859 199.790 1.00 46.70  ? 432 ILE B CA    1 
ATOM   8913  C C     . ILE D 1 461 ? 101.601 116.097 200.444 1.00 46.70  ? 432 ILE B C     1 
ATOM   8914  O O     . ILE D 1 461 ? 101.567 117.171 199.834 1.00 46.70  ? 432 ILE B O     1 
ATOM   8915  C CB    . ILE D 1 461 ? 101.115 114.093 198.982 1.00 46.70  ? 432 ILE B CB    1 
ATOM   8916  C CG1   . ILE D 1 461 ? 101.403 112.593 198.781 1.00 46.70  ? 432 ILE B CG1   1 
ATOM   8917  C CG2   . ILE D 1 461 ? 100.860 114.788 197.635 1.00 46.70  ? 432 ILE B CG2   1 
ATOM   8918  C CD1   . ILE D 1 461 ? 102.586 112.307 197.861 1.00 46.70  ? 432 ILE B CD1   1 
ATOM   8919  N N     . GLU D 1 462 ? 101.118 115.975 201.684 1.00 46.89  ? 433 GLU B N     1 
ATOM   8920  C CA    . GLU D 1 462 ? 100.617 117.157 202.382 1.00 46.89  ? 433 GLU B CA    1 
ATOM   8921  C C     . GLU D 1 462 ? 101.732 118.166 202.631 1.00 46.89  ? 433 GLU B C     1 
ATOM   8922  O O     . GLU D 1 462 ? 101.491 119.378 202.621 1.00 46.89  ? 433 GLU B O     1 
ATOM   8923  C CB    . GLU D 1 462 ? 99.961  116.758 203.705 1.00 46.89  ? 433 GLU B CB    1 
ATOM   8924  C CG    . GLU D 1 462 ? 98.690  115.929 203.562 1.00 46.89  ? 433 GLU B CG    1 
ATOM   8925  C CD    . GLU D 1 462 ? 97.480  116.750 203.141 1.00 46.89  ? 433 GLU B CD    1 
ATOM   8926  O OE1   . GLU D 1 462 ? 97.643  117.935 202.784 1.00 46.89  ? 433 GLU B OE1   1 
ATOM   8927  O OE2   . GLU D 1 462 ? 96.358  116.202 203.165 1.00 46.89  ? 433 GLU B OE2   1 
ATOM   8928  N N     . GLU D 1 463 ? 102.952 117.681 202.858 1.00 45.71  ? 434 GLU B N     1 
ATOM   8929  C CA    . GLU D 1 463 ? 104.112 118.558 202.970 1.00 45.71  ? 434 GLU B CA    1 
ATOM   8930  C C     . GLU D 1 463 ? 104.477 119.161 201.616 1.00 45.71  ? 434 GLU B C     1 
ATOM   8931  O O     . GLU D 1 463 ? 104.706 120.372 201.501 1.00 45.71  ? 434 GLU B O     1 
ATOM   8932  C CB    . GLU D 1 463 ? 105.276 117.751 203.550 1.00 45.71  ? 434 GLU B CB    1 
ATOM   8933  C CG    . GLU D 1 463 ? 106.598 118.483 203.736 1.00 45.71  ? 434 GLU B CG    1 
ATOM   8934  C CD    . GLU D 1 463 ? 107.635 117.622 204.444 1.00 45.71  ? 434 GLU B CD    1 
ATOM   8935  O OE1   . GLU D 1 463 ? 107.273 116.899 205.396 1.00 45.71  ? 434 GLU B OE1   1 
ATOM   8936  O OE2   . GLU D 1 463 ? 108.812 117.645 204.030 1.00 45.71  ? 434 GLU B OE2   1 
ATOM   8937  N N     . VAL D 1 464 ? 104.521 118.326 200.576 1.00 43.92  ? 435 VAL B N     1 
ATOM   8938  C CA    . VAL D 1 464 ? 105.067 118.744 199.288 1.00 43.92  ? 435 VAL B CA    1 
ATOM   8939  C C     . VAL D 1 464 ? 104.133 119.727 198.592 1.00 43.92  ? 435 VAL B C     1 
ATOM   8940  O O     . VAL D 1 464 ? 104.589 120.705 197.989 1.00 43.92  ? 435 VAL B O     1 
ATOM   8941  C CB    . VAL D 1 464 ? 105.366 117.495 198.432 1.00 43.92  ? 435 VAL B CB    1 
ATOM   8942  C CG1   . VAL D 1 464 ? 105.417 117.787 196.933 1.00 43.92  ? 435 VAL B CG1   1 
ATOM   8943  C CG2   . VAL D 1 464 ? 106.674 116.890 198.877 1.00 43.92  ? 435 VAL B CG2   1 
ATOM   8944  N N     . THR D 1 465 ? 102.822 119.483 198.644 1.00 41.91  ? 436 THR B N     1 
ATOM   8945  C CA    . THR D 1 465 ? 101.881 120.408 198.020 1.00 41.91  ? 436 THR B CA    1 
ATOM   8946  C C     . THR D 1 465 ? 101.883 121.764 198.716 1.00 41.91  ? 436 THR B C     1 
ATOM   8947  O O     . THR D 1 465 ? 101.567 122.779 198.085 1.00 41.91  ? 436 THR B O     1 
ATOM   8948  C CB    . THR D 1 465 ? 100.473 119.807 198.012 1.00 41.91  ? 436 THR B CB    1 
ATOM   8949  O OG1   . THR D 1 465 ? 99.629  120.578 197.149 1.00 41.91  ? 436 THR B OG1   1 
ATOM   8950  C CG2   . THR D 1 465 ? 99.866  119.774 199.414 1.00 41.91  ? 436 THR B CG2   1 
ATOM   8951  N N     . SER D 1 466 ? 102.229 121.801 200.006 1.00 43.38  ? 437 SER B N     1 
ATOM   8952  C CA    . SER D 1 466 ? 102.418 123.076 200.688 1.00 43.38  ? 437 SER B CA    1 
ATOM   8953  C C     . SER D 1 466 ? 103.725 123.735 200.270 1.00 43.38  ? 437 SER B C     1 
ATOM   8954  O O     . SER D 1 466 ? 103.783 124.959 200.107 1.00 43.38  ? 437 SER B O     1 
ATOM   8955  C CB    . SER D 1 466 ? 102.387 122.866 202.201 1.00 43.38  ? 437 SER B CB    1 
ATOM   8956  O OG    . SER D 1 466 ? 102.326 124.105 202.885 1.00 43.38  ? 437 SER B OG    1 
ATOM   8957  N N     . LEU D 1 467 ? 104.789 122.943 200.102 1.00 42.25  ? 438 LEU B N     1 
ATOM   8958  C CA    . LEU D 1 467 ? 106.085 123.512 199.740 1.00 42.25  ? 438 LEU B CA    1 
ATOM   8959  C C     . LEU D 1 467 ? 106.063 124.103 198.335 1.00 42.25  ? 438 LEU B C     1 
ATOM   8960  O O     . LEU D 1 467 ? 106.450 125.261 198.139 1.00 42.25  ? 438 LEU B O     1 
ATOM   8961  C CB    . LEU D 1 467 ? 107.177 122.446 199.852 1.00 42.25  ? 438 LEU B CB    1 
ATOM   8962  C CG    . LEU D 1 467 ? 107.564 121.970 201.255 1.00 42.25  ? 438 LEU B CG    1 
ATOM   8963  C CD1   . LEU D 1 467 ? 108.294 120.642 201.168 1.00 42.25  ? 438 LEU B CD1   1 
ATOM   8964  C CD2   . LEU D 1 467 ? 108.438 122.987 201.974 1.00 42.25  ? 438 LEU B CD2   1 
ATOM   8965  N N     . TYR D 1 468 ? 105.596 123.329 197.353 1.00 41.10  ? 439 TYR B N     1 
ATOM   8966  C CA    . TYR D 1 468 ? 105.581 123.716 195.944 1.00 41.10  ? 439 TYR B CA    1 
ATOM   8967  C C     . TYR D 1 468 ? 104.145 123.946 195.498 1.00 41.10  ? 439 TYR B C     1 
ATOM   8968  O O     . TYR D 1 468 ? 103.319 123.029 195.564 1.00 41.10  ? 439 TYR B O     1 
ATOM   8969  C CB    . TYR D 1 468 ? 106.238 122.647 195.072 1.00 41.10  ? 439 TYR B CB    1 
ATOM   8970  C CG    . TYR D 1 468 ? 107.579 122.189 195.584 1.00 41.10  ? 439 TYR B CG    1 
ATOM   8971  C CD1   . TYR D 1 468 ? 108.683 123.022 195.531 1.00 41.10  ? 439 TYR B CD1   1 
ATOM   8972  C CD2   . TYR D 1 468 ? 107.739 120.925 196.119 1.00 41.10  ? 439 TYR B CD2   1 
ATOM   8973  C CE1   . TYR D 1 468 ? 109.908 122.605 196.000 1.00 41.10  ? 439 TYR B CE1   1 
ATOM   8974  C CE2   . TYR D 1 468 ? 108.958 120.499 196.590 1.00 41.10  ? 439 TYR B CE2   1 
ATOM   8975  C CZ    . TYR D 1 468 ? 110.039 121.343 196.528 1.00 41.10  ? 439 TYR B CZ    1 
ATOM   8976  O OH    . TYR D 1 468 ? 111.258 120.925 196.999 1.00 41.10  ? 439 TYR B OH    1 
ATOM   8977  N N     . LEU D 1 469 ? 103.862 125.159 195.035 1.00 41.79  ? 440 LEU B N     1 
ATOM   8978  C CA    . LEU D 1 469 ? 102.570 125.541 194.487 1.00 41.79  ? 440 LEU B CA    1 
ATOM   8979  C C     . LEU D 1 469 ? 102.620 125.496 192.966 1.00 41.79  ? 440 LEU B C     1 
ATOM   8980  O O     . LEU D 1 469 ? 103.686 125.584 192.354 1.00 41.79  ? 440 LEU B O     1 
ATOM   8981  C CB    . LEU D 1 469 ? 102.175 126.951 194.944 1.00 41.79  ? 440 LEU B CB    1 
ATOM   8982  C CG    . LEU D 1 469 ? 101.867 127.258 196.419 1.00 41.79  ? 440 LEU B CG    1 
ATOM   8983  C CD1   . LEU D 1 469 ? 100.891 126.257 197.029 1.00 41.79  ? 440 LEU B CD1   1 
ATOM   8984  C CD2   . LEU D 1 469 ? 103.135 127.342 197.264 1.00 41.79  ? 440 LEU B CD2   1 
ATOM   8985  N N     . ASP D 1 470 ? 101.446 125.350 192.360 1.00 44.05  ? 441 ASP B N     1 
ATOM   8986  C CA    . ASP D 1 470 ? 101.332 125.461 190.916 1.00 44.05  ? 441 ASP B CA    1 
ATOM   8987  C C     . ASP D 1 470 ? 101.422 126.930 190.509 1.00 44.05  ? 441 ASP B C     1 
ATOM   8988  O O     . ASP D 1 470 ? 101.486 127.834 191.345 1.00 44.05  ? 441 ASP B O     1 
ATOM   8989  C CB    . ASP D 1 470 ? 100.028 124.834 190.436 1.00 44.05  ? 441 ASP B CB    1 
ATOM   8990  C CG    . ASP D 1 470 ? 98.813  125.592 190.910 1.00 44.05  ? 441 ASP B CG    1 
ATOM   8991  O OD1   . ASP D 1 470 ? 98.510  125.529 192.119 1.00 44.05  ? 441 ASP B OD1   1 
ATOM   8992  O OD2   . ASP D 1 470 ? 98.160  126.249 190.075 1.00 44.05  ? 441 ASP B OD2   1 
ATOM   8993  N N     . ALA D 1 471 ? 101.434 127.171 189.197 1.00 44.86  ? 442 ALA B N     1 
ATOM   8994  C CA    . ALA D 1 471 ? 101.639 128.527 188.700 1.00 44.86  ? 442 ALA B CA    1 
ATOM   8995  C C     . ALA D 1 471 ? 100.448 129.428 189.005 1.00 44.86  ? 442 ALA B C     1 
ATOM   8996  O O     . ALA D 1 471 ? 100.628 130.589 189.391 1.00 44.86  ? 442 ALA B O     1 
ATOM   8997  C CB    . ALA D 1 471 ? 101.911 128.495 187.200 1.00 44.86  ? 442 ALA B CB    1 
ATOM   8998  N N     . LYS D 1 472 ? 99.227  128.916 188.832 1.00 47.27  ? 443 LYS B N     1 
ATOM   8999  C CA    . LYS D 1 472 ? 98.039  129.737 189.057 1.00 47.27  ? 443 LYS B CA    1 
ATOM   9000  C C     . LYS D 1 472 ? 97.902  130.106 190.531 1.00 47.27  ? 443 LYS B C     1 
ATOM   9001  O O     . LYS D 1 472 ? 97.635  131.267 190.865 1.00 47.27  ? 443 LYS B O     1 
ATOM   9002  C CB    . LYS D 1 472 ? 96.798  128.989 188.552 1.00 47.27  ? 443 LYS B CB    1 
ATOM   9003  C CG    . LYS D 1 472 ? 95.410  129.508 189.005 1.00 47.27  ? 443 LYS B CG    1 
ATOM   9004  C CD    . LYS D 1 472 ? 95.159  131.007 188.748 1.00 47.27  ? 443 LYS B CD    1 
ATOM   9005  C CE    . LYS D 1 472 ? 94.971  131.329 187.267 1.00 47.27  ? 443 LYS B CE    1 
ATOM   9006  N NZ    . LYS D 1 472 ? 95.276  132.756 186.970 1.00 47.27  ? 443 LYS B NZ    1 
ATOM   9007  N N     . SER D 1 473 ? 98.098  129.133 191.426 1.00 45.25  ? 444 SER B N     1 
ATOM   9008  C CA    . SER D 1 473 ? 98.001  129.409 192.856 1.00 45.25  ? 444 SER B CA    1 
ATOM   9009  C C     . SER D 1 473 ? 99.093  130.368 193.307 1.00 45.25  ? 444 SER B C     1 
ATOM   9010  O O     . SER D 1 473 ? 98.852  131.246 194.142 1.00 45.25  ? 444 SER B O     1 
ATOM   9011  C CB    . SER D 1 473 ? 98.080  128.106 193.649 1.00 45.25  ? 444 SER B CB    1 
ATOM   9012  O OG    . SER D 1 473 ? 97.025  127.230 193.295 1.00 45.25  ? 444 SER B OG    1 
ATOM   9013  N N     . SER D 1 474 ? 100.301 130.219 192.764 1.00 45.53  ? 445 SER B N     1 
ATOM   9014  C CA    . SER D 1 474 ? 101.387 131.122 193.124 1.00 45.53  ? 445 SER B CA    1 
ATOM   9015  C C     . SER D 1 474 ? 101.120 132.539 192.635 1.00 45.53  ? 445 SER B C     1 
ATOM   9016  O O     . SER D 1 474 ? 101.403 133.508 193.348 1.00 45.53  ? 445 SER B O     1 
ATOM   9017  C CB    . SER D 1 474 ? 102.702 130.606 192.557 1.00 45.53  ? 445 SER B CB    1 
ATOM   9018  O OG    . SER D 1 474 ? 103.751 131.526 192.794 1.00 45.53  ? 445 SER B OG    1 
ATOM   9019  N N     . ALA D 1 475 ? 100.587 132.684 191.419 1.00 45.94  ? 446 ALA B N     1 
ATOM   9020  C CA    . ALA D 1 475 ? 100.249 134.014 190.923 1.00 45.94  ? 446 ALA B CA    1 
ATOM   9021  C C     . ALA D 1 475 ? 99.137  134.643 191.752 1.00 45.94  ? 446 ALA B C     1 
ATOM   9022  O O     . ALA D 1 475 ? 99.172  135.847 192.031 1.00 45.94  ? 446 ALA B O     1 
ATOM   9023  C CB    . ALA D 1 475 ? 99.848  133.944 189.453 1.00 45.94  ? 446 ALA B CB    1 
ATOM   9024  N N     . LYS D 1 476 ? 98.149  133.842 192.161 1.00 47.46  ? 447 LYS B N     1 
ATOM   9025  C CA    . LYS D 1 476 ? 97.097  134.343 193.041 1.00 47.46  ? 447 LYS B CA    1 
ATOM   9026  C C     . LYS D 1 476 ? 97.672  134.790 194.381 1.00 47.46  ? 447 LYS B C     1 
ATOM   9027  O O     . LYS D 1 476 ? 97.291  135.841 194.911 1.00 47.46  ? 447 LYS B O     1 
ATOM   9028  C CB    . LYS D 1 476 ? 96.033  133.257 193.234 1.00 47.46  ? 447 LYS B CB    1 
ATOM   9029  C CG    . LYS D 1 476 ? 94.903  133.590 194.217 1.00 47.46  ? 447 LYS B CG    1 
ATOM   9030  C CD    . LYS D 1 476 ? 93.819  132.519 194.205 1.00 47.46  ? 447 LYS B CD    1 
ATOM   9031  C CE    . LYS D 1 476 ? 92.862  132.676 193.030 1.00 47.46  ? 447 LYS B CE    1 
ATOM   9032  N NZ    . LYS D 1 476 ? 91.723  131.721 193.115 1.00 47.46  ? 447 LYS B NZ    1 
ATOM   9033  N N     . LEU D 1 477 ? 98.595  134.001 194.938 1.00 47.74  ? 448 LEU B N     1 
ATOM   9034  C CA    . LEU D 1 477 ? 99.219  134.346 196.211 1.00 47.74  ? 448 LEU B CA    1 
ATOM   9035  C C     . LEU D 1 477 ? 100.021 135.636 196.104 1.00 47.74  ? 448 LEU B C     1 
ATOM   9036  O O     . LEU D 1 477 ? 99.976  136.480 197.006 1.00 47.74  ? 448 LEU B O     1 
ATOM   9037  C CB    . LEU D 1 477 ? 100.110 133.193 196.671 1.00 47.74  ? 448 LEU B CB    1 
ATOM   9038  C CG    . LEU D 1 477 ? 100.683 133.260 198.087 1.00 47.74  ? 448 LEU B CG    1 
ATOM   9039  C CD1   . LEU D 1 477 ? 100.579 131.902 198.762 1.00 47.74  ? 448 LEU B CD1   1 
ATOM   9040  C CD2   . LEU D 1 477 ? 102.132 133.723 198.064 1.00 47.74  ? 448 LEU B CD2   1 
ATOM   9041  N N     . LEU D 1 478 ? 100.763 135.806 195.009 1.00 47.25  ? 449 LEU B N     1 
ATOM   9042  C CA    . LEU D 1 478 ? 101.524 137.039 194.827 1.00 47.25  ? 449 LEU B CA    1 
ATOM   9043  C C     . LEU D 1 478 ? 100.602 138.233 194.621 1.00 47.25  ? 449 LEU B C     1 
ATOM   9044  O O     . LEU D 1 478 ? 100.902 139.339 195.081 1.00 47.25  ? 449 LEU B O     1 
ATOM   9045  C CB    . LEU D 1 478 ? 102.496 136.915 193.652 1.00 47.25  ? 449 LEU B CB    1 
ATOM   9046  C CG    . LEU D 1 478 ? 103.938 136.581 194.037 1.00 47.25  ? 449 LEU B CG    1 
ATOM   9047  C CD1   . LEU D 1 478 ? 104.020 135.215 194.694 1.00 47.25  ? 449 LEU B CD1   1 
ATOM   9048  C CD2   . LEU D 1 478 ? 104.846 136.651 192.820 1.00 47.25  ? 449 LEU B CD2   1 
ATOM   9049  N N     . HIS D 1 479 ? 99.476  138.034 193.931 1.00 52.47  ? 450 HIS B N     1 
ATOM   9050  C CA    . HIS D 1 479 ? 98.550  139.144 193.726 1.00 52.47  ? 450 HIS B CA    1 
ATOM   9051  C C     . HIS D 1 479 ? 97.844  139.531 195.018 1.00 52.47  ? 450 HIS B C     1 
ATOM   9052  O O     . HIS D 1 479 ? 97.494  140.703 195.199 1.00 52.47  ? 450 HIS B O     1 
ATOM   9053  C CB    . HIS D 1 479 ? 97.522  138.801 192.649 1.00 52.47  ? 450 HIS B CB    1 
ATOM   9054  C CG    . HIS D 1 479 ? 97.261  139.923 191.694 1.00 52.47  ? 450 HIS B CG    1 
ATOM   9055  N ND1   . HIS D 1 479 ? 97.041  141.218 192.111 1.00 52.47  ? 450 HIS B ND1   1 
ATOM   9056  C CD2   . HIS D 1 479 ? 97.188  139.946 190.343 1.00 52.47  ? 450 HIS B CD2   1 
ATOM   9057  C CE1   . HIS D 1 479 ? 96.842  141.990 191.058 1.00 52.47  ? 450 HIS B CE1   1 
ATOM   9058  N NE2   . HIS D 1 479 ? 96.925  141.242 189.972 1.00 52.47  ? 450 HIS B NE2   1 
ATOM   9059  N N     . GLU D 1 480 ? 97.608  138.569 195.915 1.00 51.15  ? 451 GLU B N     1 
ATOM   9060  C CA    . GLU D 1 480 ? 97.049  138.906 197.221 1.00 51.15  ? 451 GLU B CA    1 
ATOM   9061  C C     . GLU D 1 480 ? 98.001  139.791 198.016 1.00 51.15  ? 451 GLU B C     1 
ATOM   9062  O O     . GLU D 1 480 ? 97.575  140.761 198.652 1.00 51.15  ? 451 GLU B O     1 
ATOM   9063  C CB    . GLU D 1 480 ? 96.730  137.635 198.007 1.00 51.15  ? 451 GLU B CB    1 
ATOM   9064  C CG    . GLU D 1 480 ? 95.460  136.925 197.570 1.00 51.15  ? 451 GLU B CG    1 
ATOM   9065  C CD    . GLU D 1 480 ? 95.015  135.873 198.566 1.00 51.15  ? 451 GLU B CD    1 
ATOM   9066  O OE1   . GLU D 1 480 ? 95.891  135.222 199.173 1.00 51.15  ? 451 GLU B OE1   1 
ATOM   9067  O OE2   . GLU D 1 480 ? 93.792  135.698 198.744 1.00 51.15  ? 451 GLU B OE2   1 
ATOM   9068  N N     . GLN D 1 481 ? 99.292  139.477 197.987 1.00 50.07  ? 452 GLN B N     1 
ATOM   9069  C CA    . GLN D 1 481 ? 100.287 140.250 198.722 1.00 50.07  ? 452 GLN B CA    1 
ATOM   9070  C C     . GLN D 1 481 ? 100.526 141.583 198.021 1.00 50.07  ? 452 GLN B C     1 
ATOM   9071  O O     . GLN D 1 481 ? 99.977  141.847 196.952 1.00 50.07  ? 452 GLN B O     1 
ATOM   9072  C CB    . GLN D 1 481 ? 101.614 139.482 198.840 1.00 50.07  ? 452 GLN B CB    1 
ATOM   9073  C CG    . GLN D 1 481 ? 101.620 138.068 199.496 1.00 50.07  ? 452 GLN B CG    1 
ATOM   9074  C CD    . GLN D 1 481 ? 100.380 137.681 200.304 1.00 50.07  ? 452 GLN B CD    1 
ATOM   9075  O OE1   . GLN D 1 481 ? 99.856  138.464 201.095 1.00 50.07  ? 452 GLN B OE1   1 
ATOM   9076  N NE2   . GLN D 1 481 ? 99.911  136.455 200.102 1.00 50.07  ? 452 GLN B NE2   1 
ATOM   9077  N N     . GLN E 2 63  ? 97.871  194.231 168.627 1.00 48.42  ? 45  GLN F N     1 
ATOM   9078  C CA    . GLN E 2 63  ? 98.667  193.701 169.769 1.00 48.42  ? 45  GLN F CA    1 
ATOM   9079  C C     . GLN E 2 63  ? 99.447  194.823 170.439 1.00 48.42  ? 45  GLN F C     1 
ATOM   9080  O O     . GLN E 2 63  ? 100.428 195.316 169.881 1.00 48.42  ? 45  GLN F O     1 
ATOM   9081  C CB    . GLN E 2 63  ? 99.631  192.608 169.293 1.00 48.42  ? 45  GLN F CB    1 
ATOM   9082  C CG    . GLN E 2 63  ? 98.976  191.402 168.627 1.00 48.42  ? 45  GLN F CG    1 
ATOM   9083  C CD    . GLN E 2 63  ? 97.962  190.708 169.513 1.00 48.42  ? 45  GLN F CD    1 
ATOM   9084  O OE1   . GLN E 2 63  ? 98.179  190.546 170.712 1.00 48.42  ? 45  GLN F OE1   1 
ATOM   9085  N NE2   . GLN E 2 63  ? 96.840  190.309 168.929 1.00 48.42  ? 45  GLN F NE2   1 
ATOM   9086  N N     . VAL E 2 64  ? 98.995  195.214 171.631 1.00 47.86  ? 46  VAL F N     1 
ATOM   9087  C CA    . VAL E 2 64  ? 99.629  196.253 172.437 1.00 47.86  ? 46  VAL F CA    1 
ATOM   9088  C C     . VAL E 2 64  ? 100.253 195.662 173.696 1.00 47.86  ? 46  VAL F C     1 
ATOM   9089  O O     . VAL E 2 64  ? 101.383 195.997 174.053 1.00 47.86  ? 46  VAL F O     1 
ATOM   9090  C CB    . VAL E 2 64  ? 98.615  197.367 172.788 1.00 47.86  ? 46  VAL F CB    1 
ATOM   9091  C CG1   . VAL E 2 64  ? 99.319  198.593 173.399 1.00 47.86  ? 46  VAL F CG1   1 
ATOM   9092  C CG2   . VAL E 2 64  ? 97.811  197.756 171.549 1.00 47.86  ? 46  VAL F CG2   1 
ATOM   9093  N N     . LYS E 2 65  ? 99.520  194.787 174.390 1.00 46.74  ? 47  LYS F N     1 
ATOM   9094  C CA    . LYS E 2 65  ? 100.073 194.141 175.578 1.00 46.74  ? 47  LYS F CA    1 
ATOM   9095  C C     . LYS E 2 65  ? 101.240 193.232 175.219 1.00 46.74  ? 47  LYS F C     1 
ATOM   9096  O O     . LYS E 2 65  ? 102.263 193.222 175.914 1.00 46.74  ? 47  LYS F O     1 
ATOM   9097  C CB    . LYS E 2 65  ? 98.994  193.345 176.316 1.00 46.74  ? 47  LYS F CB    1 
ATOM   9098  C CG    . LYS E 2 65  ? 98.416  194.065 177.521 1.00 46.74  ? 47  LYS F CG    1 
ATOM   9099  C CD    . LYS E 2 65  ? 97.436  193.185 178.280 1.00 46.74  ? 47  LYS F CD    1 
ATOM   9100  C CE    . LYS E 2 65  ? 97.063  193.793 179.623 1.00 46.74  ? 47  LYS F CE    1 
ATOM   9101  N NZ    . LYS E 2 65  ? 96.284  195.053 179.474 1.00 46.74  ? 47  LYS F NZ    1 
ATOM   9102  N N     . ALA E 2 66  ? 101.106 192.461 174.137 1.00 43.86  ? 48  ALA F N     1 
ATOM   9103  C CA    . ALA E 2 66  ? 102.195 191.590 173.710 1.00 43.86  ? 48  ALA F CA    1 
ATOM   9104  C C     . ALA E 2 66  ? 103.409 192.399 173.273 1.00 43.86  ? 48  ALA F C     1 
ATOM   9105  O O     . ALA E 2 66  ? 104.549 192.032 173.577 1.00 43.86  ? 48  ALA F O     1 
ATOM   9106  C CB    . ALA E 2 66  ? 101.724 190.677 172.580 1.00 43.86  ? 48  ALA F CB    1 
ATOM   9107  N N     . ARG E 2 67  ? 103.188 193.512 172.572 1.00 46.31  ? 49  ARG F N     1 
ATOM   9108  C CA    . ARG E 2 67  ? 104.311 194.345 172.156 1.00 46.31  ? 49  ARG F CA    1 
ATOM   9109  C C     . ARG E 2 67  ? 104.962 195.042 173.344 1.00 46.31  ? 49  ARG F C     1 
ATOM   9110  O O     . ARG E 2 67  ? 106.185 195.218 173.360 1.00 46.31  ? 49  ARG F O     1 
ATOM   9111  C CB    . ARG E 2 67  ? 103.850 195.363 171.114 1.00 46.31  ? 49  ARG F CB    1 
ATOM   9112  C CG    . ARG E 2 67  ? 103.505 194.732 169.771 1.00 46.31  ? 49  ARG F CG    1 
ATOM   9113  C CD    . ARG E 2 67  ? 103.219 195.770 168.695 1.00 46.31  ? 49  ARG F CD    1 
ATOM   9114  N NE    . ARG E 2 67  ? 104.407 196.070 167.896 1.00 46.31  ? 49  ARG F NE    1 
ATOM   9115  C CZ    . ARG E 2 67  ? 105.269 197.062 168.099 1.00 46.31  ? 49  ARG F CZ    1 
ATOM   9116  N NH1   . ARG E 2 67  ? 105.154 197.904 169.118 1.00 46.31  ? 49  ARG F NH1   1 
ATOM   9117  N NH2   . ARG E 2 67  ? 106.288 197.211 167.257 1.00 46.31  ? 49  ARG F NH2   1 
ATOM   9118  N N     . LYS E 2 68  ? 104.177 195.436 174.350 1.00 45.63  ? 50  LYS F N     1 
ATOM   9119  C CA    . LYS E 2 68  ? 104.768 195.998 175.561 1.00 45.63  ? 50  LYS F CA    1 
ATOM   9120  C C     . LYS E 2 68  ? 105.589 194.954 176.309 1.00 45.63  ? 50  LYS F C     1 
ATOM   9121  O O     . LYS E 2 68  ? 106.657 195.266 176.852 1.00 45.63  ? 50  LYS F O     1 
ATOM   9122  C CB    . LYS E 2 68  ? 103.678 196.567 176.467 1.00 45.63  ? 50  LYS F CB    1 
ATOM   9123  C CG    . LYS E 2 68  ? 104.222 197.221 177.734 1.00 45.63  ? 50  LYS F CG    1 
ATOM   9124  C CD    . LYS E 2 68  ? 103.374 198.400 178.219 1.00 45.63  ? 50  LYS F CD    1 
ATOM   9125  C CE    . LYS E 2 68  ? 101.988 197.986 178.706 1.00 45.63  ? 50  LYS F CE    1 
ATOM   9126  N NZ    . LYS E 2 68  ? 102.050 197.135 179.926 1.00 45.63  ? 50  LYS F NZ    1 
ATOM   9127  N N     . ALA E 2 69  ? 105.101 193.712 176.355 1.00 44.05  ? 51  ALA F N     1 
ATOM   9128  C CA    . ALA E 2 69  ? 105.874 192.631 176.957 1.00 44.05  ? 51  ALA F CA    1 
ATOM   9129  C C     . ALA E 2 69  ? 107.168 192.392 176.192 1.00 44.05  ? 51  ALA F C     1 
ATOM   9130  O O     . ALA E 2 69  ? 108.221 192.145 176.794 1.00 44.05  ? 51  ALA F O     1 
ATOM   9131  C CB    . ALA E 2 69  ? 105.036 191.356 176.999 1.00 44.05  ? 51  ALA F CB    1 
ATOM   9132  N N     . ALA E 2 70  ? 107.104 192.461 174.861 1.00 43.33  ? 52  ALA F N     1 
ATOM   9133  C CA    . ALA E 2 70  ? 108.309 192.342 174.049 1.00 43.33  ? 52  ALA F CA    1 
ATOM   9134  C C     . ALA E 2 70  ? 109.276 193.482 174.334 1.00 43.33  ? 52  ALA F C     1 
ATOM   9135  O O     . ALA E 2 70  ? 110.492 193.281 174.353 1.00 43.33  ? 52  ALA F O     1 
ATOM   9136  C CB    . ALA E 2 70  ? 107.941 192.310 172.567 1.00 43.33  ? 52  ALA F CB    1 
ATOM   9137  N N     . GLY E 2 71  ? 108.753 194.686 174.565 1.00 44.50  ? 53  GLY F N     1 
ATOM   9138  C CA    . GLY E 2 71  ? 109.617 195.802 174.919 1.00 44.50  ? 53  GLY F CA    1 
ATOM   9139  C C     . GLY E 2 71  ? 110.299 195.617 176.262 1.00 44.50  ? 53  GLY F C     1 
ATOM   9140  O O     . GLY E 2 71  ? 111.479 195.945 176.421 1.00 44.50  ? 53  GLY F O     1 
ATOM   9141  N N     . VAL E 2 72  ? 109.565 195.101 177.250 1.00 45.40  ? 54  VAL F N     1 
ATOM   9142  C CA    . VAL E 2 72  ? 110.161 194.844 178.561 1.00 45.40  ? 54  VAL F CA    1 
ATOM   9143  C C     . VAL E 2 72  ? 111.234 193.763 178.453 1.00 45.40  ? 54  VAL F C     1 
ATOM   9144  O O     . VAL E 2 72  ? 112.306 193.867 179.064 1.00 45.40  ? 54  VAL F O     1 
ATOM   9145  C CB    . VAL E 2 72  ? 109.066 194.471 179.580 1.00 45.40  ? 54  VAL F CB    1 
ATOM   9146  C CG1   . VAL E 2 72  ? 109.678 193.931 180.883 1.00 45.40  ? 54  VAL F CG1   1 
ATOM   9147  C CG2   . VAL E 2 72  ? 108.178 195.680 179.866 1.00 45.40  ? 54  VAL F CG2   1 
ATOM   9148  N N     . ILE E 2 73  ? 110.965 192.713 177.673 1.00 44.30  ? 55  ILE F N     1 
ATOM   9149  C CA    . ILE E 2 73  ? 111.968 191.672 177.449 1.00 44.30  ? 55  ILE F CA    1 
ATOM   9150  C C     . ILE E 2 73  ? 113.169 192.245 176.706 1.00 44.30  ? 55  ILE F C     1 
ATOM   9151  O O     . ILE E 2 73  ? 114.311 191.831 176.931 1.00 44.30  ? 55  ILE F O     1 
ATOM   9152  C CB    . ILE E 2 73  ? 111.330 190.479 176.702 1.00 44.30  ? 55  ILE F CB    1 
ATOM   9153  C CG1   . ILE E 2 73  ? 110.670 189.530 177.707 1.00 44.30  ? 55  ILE F CG1   1 
ATOM   9154  C CG2   . ILE E 2 73  ? 112.342 189.687 175.833 1.00 44.30  ? 55  ILE F CG2   1 
ATOM   9155  C CD1   . ILE E 2 73  ? 109.464 188.814 177.165 1.00 44.30  ? 55  ILE F CD1   1 
ATOM   9156  N N     . LEU E 2 74  ? 112.930 193.181 175.791 1.00 48.18  ? 56  LEU F N     1 
ATOM   9157  C CA    . LEU E 2 74  ? 114.028 193.815 175.073 1.00 48.18  ? 56  LEU F CA    1 
ATOM   9158  C C     . LEU E 2 74  ? 114.899 194.631 176.014 1.00 48.18  ? 56  LEU F C     1 
ATOM   9159  O O     . LEU E 2 74  ? 116.126 194.651 175.874 1.00 48.18  ? 56  LEU F O     1 
ATOM   9160  C CB    . LEU E 2 74  ? 113.466 194.686 173.956 1.00 48.18  ? 56  LEU F CB    1 
ATOM   9161  C CG    . LEU E 2 74  ? 114.474 195.211 172.937 1.00 48.18  ? 56  LEU F CG    1 
ATOM   9162  C CD1   . LEU E 2 74  ? 113.834 195.204 171.572 1.00 48.18  ? 56  LEU F CD1   1 
ATOM   9163  C CD2   . LEU E 2 74  ? 114.973 196.621 173.276 1.00 48.18  ? 56  LEU F CD2   1 
ATOM   9164  N N     . GLN E 2 75  ? 114.281 195.326 176.968 1.00 47.54  ? 57  GLN F N     1 
ATOM   9165  C CA    . GLN E 2 75  ? 115.072 196.040 177.966 1.00 47.54  ? 57  GLN F CA    1 
ATOM   9166  C C     . GLN E 2 75  ? 115.853 195.066 178.841 1.00 47.54  ? 57  GLN F C     1 
ATOM   9167  O O     . GLN E 2 75  ? 117.001 195.342 179.207 1.00 47.54  ? 57  GLN F O     1 
ATOM   9168  C CB    . GLN E 2 75  ? 114.183 196.940 178.828 1.00 47.54  ? 57  GLN F CB    1 
ATOM   9169  C CG    . GLN E 2 75  ? 114.134 198.410 178.392 1.00 47.54  ? 57  GLN F CG    1 
ATOM   9170  C CD    . GLN E 2 75  ? 115.455 199.147 178.575 1.00 47.54  ? 57  GLN F CD    1 
ATOM   9171  O OE1   . GLN E 2 75  ? 116.001 199.703 177.624 1.00 47.54  ? 57  GLN F OE1   1 
ATOM   9172  N NE2   . GLN E 2 75  ? 115.967 199.161 179.800 1.00 47.54  ? 57  GLN F NE2   1 
ATOM   9173  N N     . MET E 2 76  ? 115.246 193.924 179.186 1.00 47.35  ? 58  MET F N     1 
ATOM   9174  C CA    . MET E 2 76  ? 115.974 192.889 179.920 1.00 47.35  ? 58  MET F CA    1 
ATOM   9175  C C     . MET E 2 76  ? 117.171 192.385 179.121 1.00 47.35  ? 58  MET F C     1 
ATOM   9176  O O     . MET E 2 76  ? 118.230 192.093 179.687 1.00 47.35  ? 58  MET F O     1 
ATOM   9177  C CB    . MET E 2 76  ? 115.044 191.722 180.256 1.00 47.35  ? 58  MET F CB    1 
ATOM   9178  C CG    . MET E 2 76  ? 114.049 192.008 181.360 1.00 47.35  ? 58  MET F CG    1 
ATOM   9179  S SD    . MET E 2 76  ? 112.990 190.601 181.745 1.00 47.35  ? 58  MET F SD    1 
ATOM   9180  C CE    . MET E 2 76  ? 114.155 189.502 182.543 1.00 47.35  ? 58  MET F CE    1 
ATOM   9181  N N     . ILE E 2 77  ? 117.011 192.269 177.803 1.00 47.14  ? 59  ILE F N     1 
ATOM   9182  C CA    . ILE E 2 77  ? 118.118 191.874 176.935 1.00 47.14  ? 59  ILE F CA    1 
ATOM   9183  C C     . ILE E 2 77  ? 119.205 192.940 176.956 1.00 47.14  ? 59  ILE F C     1 
ATOM   9184  O O     . ILE E 2 77  ? 120.399 192.635 177.054 1.00 47.14  ? 59  ILE F O     1 
ATOM   9185  C CB    . ILE E 2 77  ? 117.604 191.619 175.503 1.00 47.14  ? 59  ILE F CB    1 
ATOM   9186  C CG1   . ILE E 2 77  ? 116.748 190.347 175.439 1.00 47.14  ? 59  ILE F CG1   1 
ATOM   9187  C CG2   . ILE E 2 77  ? 118.760 191.511 174.500 1.00 47.14  ? 59  ILE F CG2   1 
ATOM   9188  C CD1   . ILE E 2 77  ? 115.722 190.364 174.326 1.00 47.14  ? 59  ILE F CD1   1 
ATOM   9189  N N     . ARG E 2 78  ? 118.803 194.209 176.847 1.00 48.84  ? 60  ARG F N     1 
ATOM   9190  C CA    . ARG E 2 78  ? 119.770 195.296 176.727 1.00 48.84  ? 60  ARG F CA    1 
ATOM   9191  C C     . ARG E 2 78  ? 120.583 195.469 178.005 1.00 48.84  ? 60  ARG F C     1 
ATOM   9192  O O     . ARG E 2 78  ? 121.808 195.622 177.946 1.00 48.84  ? 60  ARG F O     1 
ATOM   9193  C CB    . ARG E 2 78  ? 119.054 196.594 176.358 1.00 48.84  ? 60  ARG F CB    1 
ATOM   9194  C CG    . ARG E 2 78  ? 119.995 197.733 175.993 1.00 48.84  ? 60  ARG F CG    1 
ATOM   9195  C CD    . ARG E 2 78  ? 119.245 198.919 175.418 1.00 48.84  ? 60  ARG F CD    1 
ATOM   9196  N NE    . ARG E 2 78  ? 118.883 198.683 174.019 1.00 48.84  ? 60  ARG F NE    1 
ATOM   9197  C CZ    . ARG E 2 78  ? 117.710 198.922 173.436 1.00 48.84  ? 60  ARG F CZ    1 
ATOM   9198  N NH1   . ARG E 2 78  ? 116.682 199.446 174.090 1.00 48.84  ? 60  ARG F NH1   1 
ATOM   9199  N NH2   . ARG E 2 78  ? 117.568 198.641 172.144 1.00 48.84  ? 60  ARG F NH2   1 
ATOM   9200  N N     . GLU E 2 79  ? 119.928 195.440 179.170 1.00 50.63  ? 61  GLU F N     1 
ATOM   9201  C CA    . GLU E 2 79  ? 120.671 195.455 180.428 1.00 50.63  ? 61  GLU F CA    1 
ATOM   9202  C C     . GLU E 2 79  ? 121.349 194.124 180.744 1.00 50.63  ? 61  GLU F C     1 
ATOM   9203  O O     . GLU E 2 79  ? 122.124 194.067 181.704 1.00 50.63  ? 61  GLU F O     1 
ATOM   9204  C CB    . GLU E 2 79  ? 119.761 195.847 181.594 1.00 50.63  ? 61  GLU F CB    1 
ATOM   9205  C CG    . GLU E 2 79  ? 118.922 197.101 181.355 1.00 50.63  ? 61  GLU F CG    1 
ATOM   9206  C CD    . GLU E 2 79  ? 118.321 197.678 182.629 1.00 50.63  ? 61  GLU F CD    1 
ATOM   9207  O OE1   . GLU E 2 79  ? 117.623 198.710 182.538 1.00 50.63  ? 61  GLU F OE1   1 
ATOM   9208  O OE2   . GLU E 2 79  ? 118.528 197.101 183.717 1.00 50.63  ? 61  GLU F OE2   1 
ATOM   9209  N N     . GLY E 2 80  ? 121.085 193.063 179.982 1.00 50.92  ? 62  GLY F N     1 
ATOM   9210  C CA    . GLY E 2 80  ? 121.735 191.791 180.218 1.00 50.92  ? 62  GLY F CA    1 
ATOM   9211  C C     . GLY E 2 80  ? 121.188 190.990 181.376 1.00 50.92  ? 62  GLY F C     1 
ATOM   9212  O O     . GLY E 2 80  ? 121.776 189.960 181.724 1.00 50.92  ? 62  GLY F O     1 
ATOM   9213  N N     . LYS E 2 81  ? 120.081 191.421 181.987 1.00 50.77  ? 63  LYS F N     1 
ATOM   9214  C CA    . LYS E 2 81  ? 119.522 190.678 183.107 1.00 50.77  ? 63  LYS F CA    1 
ATOM   9215  C C     . LYS E 2 81  ? 118.952 189.332 182.684 1.00 50.77  ? 63  LYS F C     1 
ATOM   9216  O O     . LYS E 2 81  ? 118.874 188.423 183.517 1.00 50.77  ? 63  LYS F O     1 
ATOM   9217  C CB    . LYS E 2 81  ? 118.442 191.508 183.798 1.00 50.77  ? 63  LYS F CB    1 
ATOM   9218  C CG    . LYS E 2 81  ? 118.994 192.700 184.557 1.00 50.77  ? 63  LYS F CG    1 
ATOM   9219  C CD    . LYS E 2 81  ? 117.893 193.466 185.270 1.00 50.77  ? 63  LYS F CD    1 
ATOM   9220  C CE    . LYS E 2 81  ? 118.462 194.441 186.288 1.00 50.77  ? 63  LYS F CE    1 
ATOM   9221  N NZ    . LYS E 2 81  ? 119.221 195.546 185.643 1.00 50.77  ? 63  LYS F NZ    1 
ATOM   9222  N N     . ILE E 2 82  ? 118.556 189.178 181.422 1.00 46.16  ? 64  ILE F N     1 
ATOM   9223  C CA    . ILE E 2 82  ? 118.116 187.881 180.922 1.00 46.16  ? 64  ILE F CA    1 
ATOM   9224  C C     . ILE E 2 82  ? 119.349 187.009 180.714 1.00 46.16  ? 64  ILE F C     1 
ATOM   9225  O O     . ILE E 2 82  ? 120.335 187.430 180.096 1.00 46.16  ? 64  ILE F O     1 
ATOM   9226  C CB    . ILE E 2 82  ? 117.282 188.041 179.635 1.00 46.16  ? 64  ILE F CB    1 
ATOM   9227  C CG1   . ILE E 2 82  ? 116.553 186.738 179.295 1.00 46.16  ? 64  ILE F CG1   1 
ATOM   9228  C CG2   . ILE E 2 82  ? 118.127 188.490 178.444 1.00 46.16  ? 64  ILE F CG2   1 
ATOM   9229  C CD1   . ILE E 2 82  ? 115.616 186.854 178.112 1.00 46.16  ? 64  ILE F CD1   1 
ATOM   9230  N N     . ALA E 2 83  ? 119.327 185.814 181.298 1.00 46.91  ? 65  ALA F N     1 
ATOM   9231  C CA    . ALA E 2 83  ? 120.470 184.914 181.235 1.00 46.91  ? 65  ALA F CA    1 
ATOM   9232  C C     . ALA E 2 83  ? 120.045 183.518 181.660 1.00 46.91  ? 65  ALA F C     1 
ATOM   9233  O O     . ALA E 2 83  ? 119.486 183.340 182.747 1.00 46.91  ? 65  ALA F O     1 
ATOM   9234  C CB    . ALA E 2 83  ? 121.609 185.421 182.120 1.00 46.91  ? 65  ALA F CB    1 
ATOM   9235  N N     . GLY E 2 84  ? 120.313 182.523 180.820 1.00 45.87  ? 66  GLY F N     1 
ATOM   9236  C CA    . GLY E 2 84  ? 119.758 181.202 181.052 1.00 45.87  ? 66  GLY F CA    1 
ATOM   9237  C C     . GLY E 2 84  ? 118.248 181.194 181.030 1.00 45.87  ? 66  GLY F C     1 
ATOM   9238  O O     . GLY E 2 84  ? 117.627 180.434 181.780 1.00 45.87  ? 66  GLY F O     1 
ATOM   9239  N N     . ARG E 2 85  ? 117.642 182.040 180.196 1.00 43.95  ? 67  ARG F N     1 
ATOM   9240  C CA    . ARG E 2 85  ? 116.199 182.202 180.110 1.00 43.95  ? 67  ARG F CA    1 
ATOM   9241  C C     . ARG E 2 85  ? 115.811 182.335 178.647 1.00 43.95  ? 67  ARG F C     1 
ATOM   9242  O O     . ARG E 2 85  ? 116.619 182.744 177.810 1.00 43.95  ? 67  ARG F O     1 
ATOM   9243  C CB    . ARG E 2 85  ? 115.719 183.434 180.890 1.00 43.95  ? 67  ARG F CB    1 
ATOM   9244  C CG    . ARG E 2 85  ? 115.832 183.300 182.408 1.00 43.95  ? 67  ARG F CG    1 
ATOM   9245  C CD    . ARG E 2 85  ? 115.675 184.632 183.137 1.00 43.95  ? 67  ARG F CD    1 
ATOM   9246  N NE    . ARG E 2 85  ? 114.274 184.979 183.352 1.00 43.95  ? 67  ARG F NE    1 
ATOM   9247  C CZ    . ARG E 2 85  ? 113.823 185.866 184.234 1.00 43.95  ? 67  ARG F CZ    1 
ATOM   9248  N NH1   . ARG E 2 85  ? 114.639 186.568 185.008 1.00 43.95  ? 67  ARG F NH1   1 
ATOM   9249  N NH2   . ARG E 2 85  ? 112.512 186.059 184.341 1.00 43.95  ? 67  ARG F NH2   1 
ATOM   9250  N N     . ALA E 2 86  ? 114.563 181.978 178.354 1.00 41.05  ? 68  ALA F N     1 
ATOM   9251  C CA    . ALA E 2 86  ? 113.987 182.031 177.018 1.00 41.05  ? 68  ALA F CA    1 
ATOM   9252  C C     . ALA E 2 86  ? 112.631 182.719 177.113 1.00 41.05  ? 68  ALA F C     1 
ATOM   9253  O O     . ALA E 2 86  ? 112.174 183.077 178.202 1.00 41.05  ? 68  ALA F O     1 
ATOM   9254  C CB    . ALA E 2 86  ? 113.883 180.623 176.419 1.00 41.05  ? 68  ALA F CB    1 
ATOM   9255  N N     . ILE E 2 87  ? 111.995 182.921 175.957 1.00 40.95  ? 69  ILE F N     1 
ATOM   9256  C CA    . ILE E 2 87  ? 110.717 183.619 175.836 1.00 40.95  ? 69  ILE F CA    1 
ATOM   9257  C C     . ILE E 2 87  ? 109.769 182.742 175.035 1.00 40.95  ? 69  ILE F C     1 
ATOM   9258  O O     . ILE E 2 87  ? 110.189 182.056 174.097 1.00 40.95  ? 69  ILE F O     1 
ATOM   9259  C CB    . ILE E 2 87  ? 110.889 185.008 175.174 1.00 40.95  ? 69  ILE F CB    1 
ATOM   9260  C CG1   . ILE E 2 87  ? 111.833 185.876 176.018 1.00 40.95  ? 69  ILE F CG1   1 
ATOM   9261  C CG2   . ILE E 2 87  ? 109.529 185.712 174.938 1.00 40.95  ? 69  ILE F CG2   1 
ATOM   9262  C CD1   . ILE E 2 87  ? 113.147 186.178 175.340 1.00 40.95  ? 69  ILE F CD1   1 
ATOM   9263  N N     . LEU E 2 88  ? 108.493 182.763 175.417 1.00 42.89  ? 70  LEU F N     1 
ATOM   9264  C CA    . LEU E 2 88  ? 107.426 182.042 174.737 1.00 42.89  ? 70  LEU F CA    1 
ATOM   9265  C C     . LEU E 2 88  ? 106.334 183.022 174.344 1.00 42.89  ? 70  LEU F C     1 
ATOM   9266  O O     . LEU E 2 88  ? 105.973 183.905 175.126 1.00 42.89  ? 70  LEU F O     1 
ATOM   9267  C CB    . LEU E 2 88  ? 106.845 180.942 175.629 1.00 42.89  ? 70  LEU F CB    1 
ATOM   9268  C CG    . LEU E 2 88  ? 105.916 179.927 174.956 1.00 42.89  ? 70  LEU F CG    1 
ATOM   9269  C CD1   . LEU E 2 88  ? 106.183 178.544 175.500 1.00 42.89  ? 70  LEU F CD1   1 
ATOM   9270  C CD2   . LEU E 2 88  ? 104.451 180.274 175.149 1.00 42.89  ? 70  LEU F CD2   1 
ATOM   9271  N N     . ILE E 2 89  ? 105.816 182.855 173.128 1.00 42.81  ? 71  ILE F N     1 
ATOM   9272  C CA    . ILE E 2 89  ? 104.743 183.682 172.581 1.00 42.81  ? 71  ILE F CA    1 
ATOM   9273  C C     . ILE E 2 89  ? 103.577 182.739 172.313 1.00 42.81  ? 71  ILE F C     1 
ATOM   9274  O O     . ILE E 2 89  ? 103.612 181.958 171.354 1.00 42.81  ? 71  ILE F O     1 
ATOM   9275  C CB    . ILE E 2 89  ? 105.168 184.428 171.305 1.00 42.81  ? 71  ILE F CB    1 
ATOM   9276  C CG1   . ILE E 2 89  ? 106.571 185.040 171.464 1.00 42.81  ? 71  ILE F CG1   1 
ATOM   9277  C CG2   . ILE E 2 89  ? 104.166 185.548 170.975 1.00 42.81  ? 71  ILE F CG2   1 
ATOM   9278  C CD1   . ILE E 2 89  ? 106.992 185.959 170.337 1.00 42.81  ? 71  ILE F CD1   1 
ATOM   9279  N N     . ALA E 2 90  ? 102.549 182.815 173.154 1.00 44.48  ? 72  ALA F N     1 
ATOM   9280  C CA    . ALA E 2 90  ? 101.376 181.956 173.080 1.00 44.48  ? 72  ALA F CA    1 
ATOM   9281  C C     . ALA E 2 90  ? 100.202 182.709 172.465 1.00 44.48  ? 72  ALA F C     1 
ATOM   9282  O O     . ALA E 2 90  ? 100.262 183.916 172.222 1.00 44.48  ? 72  ALA F O     1 
ATOM   9283  C CB    . ALA E 2 90  ? 101.001 181.445 174.473 1.00 44.48  ? 72  ALA F CB    1 
ATOM   9284  N N     . GLY E 2 91  ? 99.125  181.968 172.218 1.00 47.57  ? 73  GLY F N     1 
ATOM   9285  C CA    . GLY E 2 91  ? 97.874  182.489 171.704 1.00 47.57  ? 73  GLY F CA    1 
ATOM   9286  C C     . GLY E 2 91  ? 97.375  181.678 170.529 1.00 47.57  ? 73  GLY F C     1 
ATOM   9287  O O     . GLY E 2 91  ? 97.983  180.697 170.106 1.00 47.57  ? 73  GLY F O     1 
ATOM   9288  N N     . GLN E 2 92  ? 96.246  182.125 169.983 1.00 51.99  ? 74  GLN F N     1 
ATOM   9289  C CA    . GLN E 2 92  ? 95.621  181.422 168.874 1.00 51.99  ? 74  GLN F CA    1 
ATOM   9290  C C     . GLN E 2 92  ? 96.498  181.530 167.625 1.00 51.99  ? 74  GLN F C     1 
ATOM   9291  O O     . GLN E 2 92  ? 97.372  182.396 167.552 1.00 51.99  ? 74  GLN F O     1 
ATOM   9292  C CB    . GLN E 2 92  ? 94.227  181.985 168.591 1.00 51.99  ? 74  GLN F CB    1 
ATOM   9293  C CG    . GLN E 2 92  ? 93.087  181.252 169.293 1.00 51.99  ? 74  GLN F CG    1 
ATOM   9294  C CD    . GLN E 2 92  ? 93.324  181.061 170.780 1.00 51.99  ? 74  GLN F CD    1 
ATOM   9295  O OE1   . GLN E 2 92  ? 93.623  179.957 171.234 1.00 51.99  ? 74  GLN F OE1   1 
ATOM   9296  N NE2   . GLN E 2 92  ? 93.195  182.139 171.544 1.00 51.99  ? 74  GLN F NE2   1 
ATOM   9297  N N     . PRO E 2 93  ? 96.308  180.645 166.637 1.00 51.23  ? 75  PRO F N     1 
ATOM   9298  C CA    . PRO E 2 93  ? 97.203  180.659 165.473 1.00 51.23  ? 75  PRO F CA    1 
ATOM   9299  C C     . PRO E 2 93  ? 97.053  181.916 164.631 1.00 51.23  ? 75  PRO F C     1 
ATOM   9300  O O     . PRO E 2 93  ? 95.978  182.514 164.539 1.00 51.23  ? 75  PRO F O     1 
ATOM   9301  C CB    . PRO E 2 93  ? 96.779  179.418 164.674 1.00 51.23  ? 75  PRO F CB    1 
ATOM   9302  C CG    . PRO E 2 93  ? 95.892  178.641 165.567 1.00 51.23  ? 75  PRO F CG    1 
ATOM   9303  C CD    . PRO E 2 93  ? 95.253  179.626 166.469 1.00 51.23  ? 75  PRO F CD    1 
ATOM   9304  N N     . GLY E 2 94  ? 98.162  182.314 164.014 1.00 49.97  ? 76  GLY F N     1 
ATOM   9305  C CA    . GLY E 2 94  ? 98.143  183.409 163.067 1.00 49.97  ? 76  GLY F CA    1 
ATOM   9306  C C     . GLY E 2 94  ? 97.948  184.785 163.660 1.00 49.97  ? 76  GLY F C     1 
ATOM   9307  O O     . GLY E 2 94  ? 97.580  185.706 162.926 1.00 49.97  ? 76  GLY F O     1 
ATOM   9308  N N     . THR E 2 95  ? 98.191  184.959 164.959 1.00 48.01  ? 77  THR F N     1 
ATOM   9309  C CA    . THR E 2 95  ? 98.048  186.257 165.626 1.00 48.01  ? 77  THR F CA    1 
ATOM   9310  C C     . THR E 2 95  ? 99.376  187.015 165.659 1.00 48.01  ? 77  THR F C     1 
ATOM   9311  O O     . THR E 2 95  ? 99.796  187.533 166.692 1.00 48.01  ? 77  THR F O     1 
ATOM   9312  C CB    . THR E 2 95  ? 97.499  186.047 167.034 1.00 48.01  ? 77  THR F CB    1 
ATOM   9313  O OG1   . THR E 2 95  ? 96.483  185.036 167.004 1.00 48.01  ? 77  THR F OG1   1 
ATOM   9314  C CG2   . THR E 2 95  ? 96.877  187.330 167.580 1.00 48.01  ? 77  THR F CG2   1 
ATOM   9315  N N     . GLY E 2 96  ? 100.039 187.086 164.505 1.00 47.12  ? 78  GLY F N     1 
ATOM   9316  C CA    . GLY E 2 96  ? 101.227 187.911 164.335 1.00 47.12  ? 78  GLY F CA    1 
ATOM   9317  C C     . GLY E 2 96  ? 102.390 187.584 165.246 1.00 47.12  ? 78  GLY F C     1 
ATOM   9318  O O     . GLY E 2 96  ? 103.150 188.489 165.600 1.00 47.12  ? 78  GLY F O     1 
ATOM   9319  N N     . LYS E 2 97  ? 102.553 186.317 165.640 1.00 45.79  ? 79  LYS F N     1 
ATOM   9320  C CA    . LYS E 2 97  ? 103.637 185.958 166.554 1.00 45.79  ? 79  LYS F CA    1 
ATOM   9321  C C     . LYS E 2 97  ? 105.000 186.173 165.909 1.00 45.79  ? 79  LYS F C     1 
ATOM   9322  O O     . LYS E 2 97  ? 105.918 186.722 166.537 1.00 45.79  ? 79  LYS F O     1 
ATOM   9323  C CB    . LYS E 2 97  ? 103.489 184.503 166.996 1.00 45.79  ? 79  LYS F CB    1 
ATOM   9324  C CG    . LYS E 2 97  ? 102.296 184.236 167.891 1.00 45.79  ? 79  LYS F CG    1 
ATOM   9325  C CD    . LYS E 2 97  ? 101.853 182.785 167.781 1.00 45.79  ? 79  LYS F CD    1 
ATOM   9326  C CE    . LYS E 2 97  ? 100.901 182.395 168.897 1.00 45.79  ? 79  LYS F CE    1 
ATOM   9327  N NZ    . LYS E 2 97  ? 99.612  183.137 168.837 1.00 45.79  ? 79  LYS F NZ    1 
ATOM   9328  N N     . THR E 2 98  ? 105.145 185.759 164.648 1.00 48.19  ? 80  THR F N     1 
ATOM   9329  C CA    . THR E 2 98  ? 106.390 185.996 163.930 1.00 48.19  ? 80  THR F CA    1 
ATOM   9330  C C     . THR E 2 98  ? 106.640 187.483 163.734 1.00 48.19  ? 80  THR F C     1 
ATOM   9331  O O     . THR E 2 98  ? 107.797 187.914 163.692 1.00 48.19  ? 80  THR F O     1 
ATOM   9332  C CB    . THR E 2 98  ? 106.361 185.278 162.580 1.00 48.19  ? 80  THR F CB    1 
ATOM   9333  O OG1   . THR E 2 98  ? 105.897 183.935 162.762 1.00 48.19  ? 80  THR F OG1   1 
ATOM   9334  C CG2   . THR E 2 98  ? 107.747 185.252 161.940 1.00 48.19  ? 80  THR F CG2   1 
ATOM   9335  N N     . ALA E 2 99  ? 105.576 188.283 163.620 1.00 48.83  ? 81  ALA F N     1 
ATOM   9336  C CA    . ALA E 2 99  ? 105.748 189.729 163.560 1.00 48.83  ? 81  ALA F CA    1 
ATOM   9337  C C     . ALA E 2 99  ? 106.372 190.257 164.844 1.00 48.83  ? 81  ALA F C     1 
ATOM   9338  O O     . ALA E 2 99  ? 107.271 191.101 164.796 1.00 48.83  ? 81  ALA F O     1 
ATOM   9339  C CB    . ALA E 2 99  ? 104.409 190.413 163.293 1.00 48.83  ? 81  ALA F CB    1 
ATOM   9340  N N     . ILE E 2 100 ? 105.932 189.745 166.000 1.00 46.60  ? 82  ILE F N     1 
ATOM   9341  C CA    . ILE E 2 100 ? 106.534 190.136 167.276 1.00 46.60  ? 82  ILE F CA    1 
ATOM   9342  C C     . ILE E 2 100 ? 107.995 189.706 167.325 1.00 46.60  ? 82  ILE F C     1 
ATOM   9343  O O     . ILE E 2 100 ? 108.859 190.457 167.797 1.00 46.60  ? 82  ILE F O     1 
ATOM   9344  C CB    . ILE E 2 100 ? 105.725 189.554 168.458 1.00 46.60  ? 82  ILE F CB    1 
ATOM   9345  C CG1   . ILE E 2 100 ? 104.287 190.125 168.417 1.00 46.60  ? 82  ILE F CG1   1 
ATOM   9346  C CG2   . ILE E 2 100 ? 106.514 189.790 169.807 1.00 46.60  ? 82  ILE F CG2   1 
ATOM   9347  C CD1   . ILE E 2 100 ? 103.388 189.894 169.634 1.00 46.60  ? 82  ILE F CD1   1 
ATOM   9348  N N     . ALA E 2 101 ? 108.291 188.492 166.850 1.00 48.25  ? 83  ALA F N     1 
ATOM   9349  C CA    . ALA E 2 101 ? 109.661 187.984 166.912 1.00 48.25  ? 83  ALA F CA    1 
ATOM   9350  C C     . ALA E 2 101 ? 110.608 188.820 166.054 1.00 48.25  ? 83  ALA F C     1 
ATOM   9351  O O     . ALA E 2 101 ? 111.656 189.278 166.529 1.00 48.25  ? 83  ALA F O     1 
ATOM   9352  C CB    . ALA E 2 101 ? 109.695 186.520 166.476 1.00 48.25  ? 83  ALA F CB    1 
ATOM   9353  N N     . MET E 2 102 ? 110.246 189.046 164.787 1.00 53.20  ? 84  MET F N     1 
ATOM   9354  C CA    . MET E 2 102 ? 111.085 189.875 163.926 1.00 53.20  ? 84  MET F CA    1 
ATOM   9355  C C     . MET E 2 102 ? 111.123 191.324 164.391 1.00 53.20  ? 84  MET F C     1 
ATOM   9356  O O     . MET E 2 102 ? 112.149 191.990 164.220 1.00 53.20  ? 84  MET F O     1 
ATOM   9357  C CB    . MET E 2 102 ? 110.615 189.799 162.473 1.00 53.20  ? 84  MET F CB    1 
ATOM   9358  C CG    . MET E 2 102 ? 110.592 188.374 161.893 1.00 53.20  ? 84  MET F CG    1 
ATOM   9359  S SD    . MET E 2 102 ? 110.565 188.115 160.089 1.00 53.20  ? 84  MET F SD    1 
ATOM   9360  C CE    . MET E 2 102 ? 110.549 189.757 159.363 1.00 53.20  ? 84  MET F CE    1 
ATOM   9361  N N     . GLY E 2 103 ? 110.037 191.832 164.981 1.00 52.24  ? 85  GLY F N     1 
ATOM   9362  C CA    . GLY E 2 103 ? 110.067 193.180 165.519 1.00 52.24  ? 85  GLY F CA    1 
ATOM   9363  C C     . GLY E 2 103 ? 111.059 193.324 166.655 1.00 52.24  ? 85  GLY F C     1 
ATOM   9364  O O     . GLY E 2 103 ? 111.817 194.294 166.707 1.00 52.24  ? 85  GLY F O     1 
ATOM   9365  N N     . MET E 2 104 ? 111.086 192.345 167.563 1.00 50.43  ? 86  MET F N     1 
ATOM   9366  C CA    . MET E 2 104 ? 112.075 192.360 168.640 1.00 50.43  ? 86  MET F CA    1 
ATOM   9367  C C     . MET E 2 104 ? 113.487 192.233 168.074 1.00 50.43  ? 86  MET F C     1 
ATOM   9368  O O     . MET E 2 104 ? 114.414 192.912 168.540 1.00 50.43  ? 86  MET F O     1 
ATOM   9369  C CB    . MET E 2 104 ? 111.772 191.236 169.646 1.00 50.43  ? 86  MET F CB    1 
ATOM   9370  C CG    . MET E 2 104 ? 112.973 190.617 170.395 1.00 50.43  ? 86  MET F CG    1 
ATOM   9371  S SD    . MET E 2 104 ? 112.548 189.722 171.912 1.00 50.43  ? 86  MET F SD    1 
ATOM   9372  C CE    . MET E 2 104 ? 110.909 189.078 171.573 1.00 50.43  ? 86  MET F CE    1 
ATOM   9373  N N     . ALA E 2 105 ? 113.666 191.371 167.067 1.00 53.01  ? 87  ALA F N     1 
ATOM   9374  C CA    . ALA E 2 105 ? 114.994 191.159 166.496 1.00 53.01  ? 87  ALA F CA    1 
ATOM   9375  C C     . ALA E 2 105 ? 115.525 192.420 165.823 1.00 53.01  ? 87  ALA F C     1 
ATOM   9376  O O     . ALA E 2 105 ? 116.700 192.768 165.984 1.00 53.01  ? 87  ALA F O     1 
ATOM   9377  C CB    . ALA E 2 105 ? 114.956 190.001 165.500 1.00 53.01  ? 87  ALA F CB    1 
ATOM   9378  N N     . LYS E 2 106 ? 114.675 193.118 165.066 1.00 55.07  ? 88  LYS F N     1 
ATOM   9379  C CA    . LYS E 2 106 ? 115.100 194.371 164.449 1.00 55.07  ? 88  LYS F CA    1 
ATOM   9380  C C     . LYS E 2 106 ? 115.259 195.477 165.484 1.00 55.07  ? 88  LYS F C     1 
ATOM   9381  O O     . LYS E 2 106 ? 116.134 196.337 165.337 1.00 55.07  ? 88  LYS F O     1 
ATOM   9382  C CB    . LYS E 2 106 ? 114.100 194.811 163.372 1.00 55.07  ? 88  LYS F CB    1 
ATOM   9383  C CG    . LYS E 2 106 ? 113.867 193.870 162.160 1.00 55.07  ? 88  LYS F CG    1 
ATOM   9384  C CD    . LYS E 2 106 ? 114.988 192.865 161.872 1.00 55.07  ? 88  LYS F CD    1 
ATOM   9385  C CE    . LYS E 2 106 ? 114.791 192.154 160.538 1.00 55.07  ? 88  LYS F CE    1 
ATOM   9386  N NZ    . LYS E 2 106 ? 113.722 191.121 160.606 1.00 55.07  ? 88  LYS F NZ    1 
ATOM   9387  N N     . SER E 2 107 ? 114.433 195.476 166.533 1.00 51.68  ? 89  SER F N     1 
ATOM   9388  C CA    . SER E 2 107 ? 114.533 196.510 167.552 1.00 51.68  ? 89  SER F CA    1 
ATOM   9389  C C     . SER E 2 107 ? 115.814 196.381 168.365 1.00 51.68  ? 89  SER F C     1 
ATOM   9390  O O     . SER E 2 107 ? 116.340 197.391 168.846 1.00 51.68  ? 89  SER F O     1 
ATOM   9391  C CB    . SER E 2 107 ? 113.303 196.458 168.452 1.00 51.68  ? 89  SER F CB    1 
ATOM   9392  O OG    . SER E 2 107 ? 113.348 197.470 169.441 1.00 51.68  ? 89  SER F OG    1 
ATOM   9393  N N     . LEU E 2 108 ? 116.328 195.161 168.541 1.00 52.65  ? 90  LEU F N     1 
ATOM   9394  C CA    . LEU E 2 108 ? 117.691 195.024 169.049 1.00 52.65  ? 90  LEU F CA    1 
ATOM   9395  C C     . LEU E 2 108 ? 118.690 195.646 168.084 1.00 52.65  ? 90  LEU F C     1 
ATOM   9396  O O     . LEU E 2 108 ? 119.644 196.310 168.505 1.00 52.65  ? 90  LEU F O     1 
ATOM   9397  C CB    . LEU E 2 108 ? 118.039 193.552 169.285 1.00 52.65  ? 90  LEU F CB    1 
ATOM   9398  C CG    . LEU E 2 108 ? 117.382 192.760 170.422 1.00 52.65  ? 90  LEU F CG    1 
ATOM   9399  C CD1   . LEU E 2 108 ? 117.915 191.340 170.432 1.00 52.65  ? 90  LEU F CD1   1 
ATOM   9400  C CD2   . LEU E 2 108 ? 117.642 193.392 171.777 1.00 52.65  ? 90  LEU F CD2   1 
ATOM   9401  N N     . GLY E 2 109 ? 118.483 195.443 166.786 1.00 63.11  ? 91  GLY F N     1 
ATOM   9402  C CA    . GLY E 2 109 ? 119.354 195.996 165.770 1.00 63.11  ? 91  GLY F CA    1 
ATOM   9403  C C     . GLY E 2 109 ? 119.226 195.252 164.458 1.00 63.11  ? 91  GLY F C     1 
ATOM   9404  O O     . GLY E 2 109 ? 119.107 194.024 164.444 1.00 63.11  ? 91  GLY F O     1 
ATOM   9405  N N     . LEU E 2 110 ? 119.236 195.990 163.345 1.00 66.41  ? 92  LEU F N     1 
ATOM   9406  C CA    . LEU E 2 110 ? 119.186 195.348 162.037 1.00 66.41  ? 92  LEU F CA    1 
ATOM   9407  C C     . LEU E 2 110 ? 120.435 194.516 161.778 1.00 66.41  ? 92  LEU F C     1 
ATOM   9408  O O     . LEU E 2 110 ? 120.366 193.492 161.091 1.00 66.41  ? 92  LEU F O     1 
ATOM   9409  C CB    . LEU E 2 110 ? 119.016 196.402 160.943 1.00 66.41  ? 92  LEU F CB    1 
ATOM   9410  C CG    . LEU E 2 110 ? 117.670 197.134 160.915 1.00 66.41  ? 92  LEU F CG    1 
ATOM   9411  C CD1   . LEU E 2 110 ? 117.776 198.406 160.087 1.00 66.41  ? 92  LEU F CD1   1 
ATOM   9412  C CD2   . LEU E 2 110 ? 116.558 196.236 160.381 1.00 66.41  ? 92  LEU F CD2   1 
ATOM   9413  N N     . GLU E 2 111 ? 121.580 194.942 162.315 1.00 71.77  ? 93  GLU F N     1 
ATOM   9414  C CA    . GLU E 2 111 ? 122.806 194.162 162.188 1.00 71.77  ? 93  GLU F CA    1 
ATOM   9415  C C     . GLU E 2 111 ? 122.729 192.820 162.909 1.00 71.77  ? 93  GLU F C     1 
ATOM   9416  O O     . GLU E 2 111 ? 123.442 191.888 162.523 1.00 71.77  ? 93  GLU F O     1 
ATOM   9417  C CB    . GLU E 2 111 ? 124.006 194.967 162.708 1.00 71.77  ? 93  GLU F CB    1 
ATOM   9418  C CG    . GLU E 2 111 ? 123.906 195.475 164.154 1.00 71.77  ? 93  GLU F CG    1 
ATOM   9419  C CD    . GLU E 2 111 ? 123.468 196.925 164.239 1.00 71.77  ? 93  GLU F CD    1 
ATOM   9420  O OE1   . GLU E 2 111 ? 122.573 197.322 163.464 1.00 71.77  ? 93  GLU F OE1   1 
ATOM   9421  O OE2   . GLU E 2 111 ? 124.016 197.666 165.081 1.00 71.77  ? 93  GLU F OE2   1 
ATOM   9422  N N     . THR E 2 112 ? 121.892 192.696 163.939 1.00 65.77  ? 94  THR F N     1 
ATOM   9423  C CA    . THR E 2 112 ? 121.827 191.445 164.680 1.00 65.77  ? 94  THR F CA    1 
ATOM   9424  C C     . THR E 2 112 ? 121.111 190.385 163.837 1.00 65.77  ? 94  THR F C     1 
ATOM   9425  O O     . THR E 2 112 ? 120.159 190.713 163.122 1.00 65.77  ? 94  THR F O     1 
ATOM   9426  C CB    . THR E 2 112 ? 121.090 191.627 166.009 1.00 65.77  ? 94  THR F CB    1 
ATOM   9427  O OG1   . THR E 2 112 ? 119.695 191.837 165.759 1.00 65.77  ? 94  THR F OG1   1 
ATOM   9428  C CG2   . THR E 2 112 ? 121.657 192.804 166.800 1.00 65.77  ? 94  THR F CG2   1 
ATOM   9429  N N     . PRO E 2 113 ? 121.520 189.114 163.898 1.00 61.30  ? 95  PRO F N     1 
ATOM   9430  C CA    . PRO E 2 113 ? 120.907 188.109 163.024 1.00 61.30  ? 95  PRO F CA    1 
ATOM   9431  C C     . PRO E 2 113 ? 119.591 187.587 163.591 1.00 61.30  ? 95  PRO F C     1 
ATOM   9432  O O     . PRO E 2 113 ? 119.196 187.887 164.717 1.00 61.30  ? 95  PRO F O     1 
ATOM   9433  C CB    . PRO E 2 113 ? 121.964 187.006 162.962 1.00 61.30  ? 95  PRO F CB    1 
ATOM   9434  C CG    . PRO E 2 113 ? 122.650 187.082 164.253 1.00 61.30  ? 95  PRO F CG    1 
ATOM   9435  C CD    . PRO E 2 113 ? 122.567 188.499 164.740 1.00 61.30  ? 95  PRO F CD    1 
ATOM   9436  N N     . PHE E 2 114 ? 118.913 186.790 162.767 1.00 51.86  ? 96  PHE F N     1 
ATOM   9437  C CA    . PHE E 2 114 ? 117.626 186.200 163.106 1.00 51.86  ? 96  PHE F CA    1 
ATOM   9438  C C     . PHE E 2 114 ? 117.518 184.880 162.356 1.00 51.86  ? 96  PHE F C     1 
ATOM   9439  O O     . PHE E 2 114 ? 118.097 184.723 161.278 1.00 51.86  ? 96  PHE F O     1 
ATOM   9440  C CB    . PHE E 2 114 ? 116.478 187.160 162.746 1.00 51.86  ? 96  PHE F CB    1 
ATOM   9441  C CG    . PHE E 2 114 ? 115.104 186.630 163.054 1.00 51.86  ? 96  PHE F CG    1 
ATOM   9442  C CD1   . PHE E 2 114 ? 114.552 186.797 164.310 1.00 51.86  ? 96  PHE F CD1   1 
ATOM   9443  C CD2   . PHE E 2 114 ? 114.360 185.981 162.084 1.00 51.86  ? 96  PHE F CD2   1 
ATOM   9444  C CE1   . PHE E 2 114 ? 113.289 186.317 164.598 1.00 51.86  ? 96  PHE F CE1   1 
ATOM   9445  C CE2   . PHE E 2 114 ? 113.098 185.499 162.367 1.00 51.86  ? 96  PHE F CE2   1 
ATOM   9446  C CZ    . PHE E 2 114 ? 112.562 185.669 163.625 1.00 51.86  ? 96  PHE F CZ    1 
ATOM   9447  N N     . ALA E 2 115 ? 116.784 183.927 162.934 1.00 53.07  ? 97  ALA F N     1 
ATOM   9448  C CA    . ALA E 2 115 ? 116.653 182.598 162.340 1.00 53.07  ? 97  ALA F CA    1 
ATOM   9449  C C     . ALA E 2 115 ? 115.321 181.993 162.763 1.00 53.07  ? 97  ALA F C     1 
ATOM   9450  O O     . ALA E 2 115 ? 115.119 181.711 163.947 1.00 53.07  ? 97  ALA F O     1 
ATOM   9451  C CB    . ALA E 2 115 ? 117.813 181.699 162.756 1.00 53.07  ? 97  ALA F CB    1 
ATOM   9452  N N     . MET E 2 116 ? 114.427 181.795 161.791 1.00 53.45  ? 98  MET F N     1 
ATOM   9453  C CA    . MET E 2 116 ? 113.155 181.097 161.969 1.00 53.45  ? 98  MET F CA    1 
ATOM   9454  C C     . MET E 2 116 ? 113.279 179.762 161.242 1.00 53.45  ? 98  MET F C     1 
ATOM   9455  O O     . MET E 2 116 ? 113.263 179.728 160.006 1.00 53.45  ? 98  MET F O     1 
ATOM   9456  C CB    . MET E 2 116 ? 111.997 181.927 161.419 1.00 53.45  ? 98  MET F CB    1 
ATOM   9457  C CG    . MET E 2 116 ? 110.624 181.279 161.576 1.00 53.45  ? 98  MET F CG    1 
ATOM   9458  S SD    . MET E 2 116 ? 109.891 180.786 160.006 1.00 53.45  ? 98  MET F SD    1 
ATOM   9459  C CE    . MET E 2 116 ? 109.595 182.382 159.245 1.00 53.45  ? 98  MET F CE    1 
ATOM   9460  N N     . ILE E 2 117 ? 113.377 178.669 162.010 1.00 60.22  ? 99  ILE F N     1 
ATOM   9461  C CA    . ILE E 2 117 ? 113.821 177.373 161.489 1.00 60.22  ? 99  ILE F CA    1 
ATOM   9462  C C     . ILE E 2 117 ? 112.775 176.295 161.778 1.00 60.22  ? 99  ILE F C     1 
ATOM   9463  O O     . ILE E 2 117 ? 112.581 175.373 160.978 1.00 60.22  ? 99  ILE F O     1 
ATOM   9464  C CB    . ILE E 2 117 ? 115.199 177.005 162.105 1.00 60.22  ? 99  ILE F CB    1 
ATOM   9465  C CG1   . ILE E 2 117 ? 115.657 175.555 161.826 1.00 60.22  ? 99  ILE F CG1   1 
ATOM   9466  C CG2   . ILE E 2 117 ? 115.218 177.240 163.628 1.00 60.22  ? 99  ILE F CG2   1 
ATOM   9467  C CD1   . ILE E 2 117 ? 115.700 175.155 160.354 1.00 60.22  ? 99  ILE F CD1   1 
ATOM   9468  N N     . ALA E 2 118 ? 112.043 176.428 162.876 1.00 57.93  ? 100 ALA F N     1 
ATOM   9469  C CA    . ALA E 2 118 ? 111.461 175.276 163.536 1.00 57.93  ? 100 ALA F CA    1 
ATOM   9470  C C     . ALA E 2 118 ? 110.012 175.056 163.111 1.00 57.93  ? 100 ALA F C     1 
ATOM   9471  O O     . ALA E 2 118 ? 109.502 175.698 162.187 1.00 57.93  ? 100 ALA F O     1 
ATOM   9472  C CB    . ALA E 2 118 ? 111.583 175.459 165.043 1.00 57.93  ? 100 ALA F CB    1 
ATOM   9473  N N     . GLY E 2 119 ? 109.342 174.139 163.815 1.00 61.82  ? 101 GLY F N     1 
ATOM   9474  C CA    . GLY E 2 119 ? 108.010 173.669 163.495 1.00 61.82  ? 101 GLY F CA    1 
ATOM   9475  C C     . GLY E 2 119 ? 108.084 172.202 163.143 1.00 61.82  ? 101 GLY F C     1 
ATOM   9476  O O     . GLY E 2 119 ? 108.913 171.473 163.696 1.00 61.82  ? 101 GLY F O     1 
ATOM   9477  N N     . SER E 2 120 ? 107.226 171.758 162.228 1.00 65.93  ? 102 SER F N     1 
ATOM   9478  C CA    . SER E 2 120 ? 107.411 170.472 161.569 1.00 65.93  ? 102 SER F CA    1 
ATOM   9479  C C     . SER E 2 120 ? 108.422 170.537 160.424 1.00 65.93  ? 102 SER F C     1 
ATOM   9480  O O     . SER E 2 120 ? 108.593 169.534 159.724 1.00 65.93  ? 102 SER F O     1 
ATOM   9481  C CB    . SER E 2 120 ? 106.069 169.953 161.053 1.00 65.93  ? 102 SER F CB    1 
ATOM   9482  O OG    . SER E 2 120 ? 106.183 168.613 160.605 1.00 65.93  ? 102 SER F OG    1 
ATOM   9483  N N     . GLU E 2 121 ? 109.062 171.691 160.194 1.00 68.99  ? 103 GLU F N     1 
ATOM   9484  C CA    . GLU E 2 121 ? 110.177 171.770 159.257 1.00 68.99  ? 103 GLU F CA    1 
ATOM   9485  C C     . GLU E 2 121 ? 111.295 170.823 159.668 1.00 68.99  ? 103 GLU F C     1 
ATOM   9486  O O     . GLU E 2 121 ? 111.846 170.091 158.840 1.00 68.99  ? 103 GLU F O     1 
ATOM   9487  C CB    . GLU E 2 121 ? 110.680 173.212 159.187 1.00 68.99  ? 103 GLU F CB    1 
ATOM   9488  C CG    . GLU E 2 121 ? 111.971 173.389 158.401 1.00 68.99  ? 103 GLU F CG    1 
ATOM   9489  C CD    . GLU E 2 121 ? 112.137 174.792 157.844 1.00 68.99  ? 103 GLU F CD    1 
ATOM   9490  O OE1   . GLU E 2 121 ? 111.196 175.301 157.200 1.00 68.99  ? 103 GLU F OE1   1 
ATOM   9491  O OE2   . GLU E 2 121 ? 113.212 175.390 158.051 1.00 68.99  ? 103 GLU F OE2   1 
ATOM   9492  N N     . ILE E 2 122 ? 111.641 170.826 160.956 1.00 67.52  ? 104 ILE F N     1 
ATOM   9493  C CA    . ILE E 2 122 ? 112.485 169.769 161.500 1.00 67.52  ? 104 ILE F CA    1 
ATOM   9494  C C     . ILE E 2 122 ? 111.731 168.444 161.381 1.00 67.52  ? 104 ILE F C     1 
ATOM   9495  O O     . ILE E 2 122 ? 110.498 168.408 161.298 1.00 67.52  ? 104 ILE F O     1 
ATOM   9496  C CB    . ILE E 2 122 ? 112.876 170.088 162.961 1.00 67.52  ? 104 ILE F CB    1 
ATOM   9497  C CG1   . ILE E 2 122 ? 113.533 171.483 163.094 1.00 67.52  ? 104 ILE F CG1   1 
ATOM   9498  C CG2   . ILE E 2 122 ? 113.821 169.025 163.569 1.00 67.52  ? 104 ILE F CG2   1 
ATOM   9499  C CD1   . ILE E 2 122 ? 114.747 171.739 162.201 1.00 67.52  ? 104 ILE F CD1   1 
ATOM   9500  N N     . PHE E 2 123 ? 112.490 167.341 161.348 1.00 67.11  ? 105 PHE F N     1 
ATOM   9501  C CA    . PHE E 2 123 ? 112.014 165.975 161.108 1.00 67.11  ? 105 PHE F CA    1 
ATOM   9502  C C     . PHE E 2 123 ? 111.585 165.738 159.661 1.00 67.11  ? 105 PHE F C     1 
ATOM   9503  O O     . PHE E 2 123 ? 110.872 164.764 159.392 1.00 67.11  ? 105 PHE F O     1 
ATOM   9504  C CB    . PHE E 2 123 ? 110.852 165.564 162.034 1.00 67.11  ? 105 PHE F CB    1 
ATOM   9505  C CG    . PHE E 2 123 ? 111.031 165.959 163.473 1.00 67.11  ? 105 PHE F CG    1 
ATOM   9506  C CD1   . PHE E 2 123 ? 111.958 165.322 164.274 1.00 67.11  ? 105 PHE F CD1   1 
ATOM   9507  C CD2   . PHE E 2 123 ? 110.260 166.970 164.023 1.00 67.11  ? 105 PHE F CD2   1 
ATOM   9508  C CE1   . PHE E 2 123 ? 112.114 165.689 165.596 1.00 67.11  ? 105 PHE F CE1   1 
ATOM   9509  C CE2   . PHE E 2 123 ? 110.417 167.341 165.339 1.00 67.11  ? 105 PHE F CE2   1 
ATOM   9510  C CZ    . PHE E 2 123 ? 111.344 166.699 166.127 1.00 67.11  ? 105 PHE F CZ    1 
ATOM   9511  N N     . SER E 2 124 ? 111.982 166.612 158.724 1.00 70.56  ? 106 SER F N     1 
ATOM   9512  C CA    . SER E 2 124 ? 111.702 166.440 157.299 1.00 70.56  ? 106 SER F CA    1 
ATOM   9513  C C     . SER E 2 124 ? 112.884 166.740 156.389 1.00 70.56  ? 106 SER F C     1 
ATOM   9514  O O     . SER E 2 124 ? 112.900 166.239 155.258 1.00 70.56  ? 106 SER F O     1 
ATOM   9515  C CB    . SER E 2 124 ? 110.525 167.329 156.874 1.00 70.56  ? 106 SER F CB    1 
ATOM   9516  O OG    . SER E 2 124 ? 110.849 168.700 157.011 1.00 70.56  ? 106 SER F OG    1 
ATOM   9517  N N     . LEU E 2 125 ? 113.863 167.528 156.825 1.00 76.76  ? 107 LEU F N     1 
ATOM   9518  C CA    . LEU E 2 125 ? 115.017 167.822 155.992 1.00 76.76  ? 107 LEU F CA    1 
ATOM   9519  C C     . LEU E 2 125 ? 115.918 166.595 155.858 1.00 76.76  ? 107 LEU F C     1 
ATOM   9520  O O     . LEU E 2 125 ? 115.814 165.622 156.610 1.00 76.76  ? 107 LEU F O     1 
ATOM   9521  C CB    . LEU E 2 125 ? 115.813 169.000 156.565 1.00 76.76  ? 107 LEU F CB    1 
ATOM   9522  C CG    . LEU E 2 125 ? 115.336 170.404 156.173 1.00 76.76  ? 107 LEU F CG    1 
ATOM   9523  C CD1   . LEU E 2 125 ? 114.145 170.839 156.999 1.00 76.76  ? 107 LEU F CD1   1 
ATOM   9524  C CD2   . LEU E 2 125 ? 116.474 171.408 156.311 1.00 76.76  ? 107 LEU F CD2   1 
ATOM   9525  N N     . GLU E 2 126 ? 116.810 166.658 154.864 1.00 85.89  ? 108 GLU F N     1 
ATOM   9526  C CA    . GLU E 2 126 ? 117.778 165.587 154.637 1.00 85.89  ? 108 GLU F CA    1 
ATOM   9527  C C     . GLU E 2 126 ? 118.710 165.368 155.830 1.00 85.89  ? 108 GLU F C     1 
ATOM   9528  O O     . GLU E 2 126 ? 119.210 164.252 156.015 1.00 85.89  ? 108 GLU F O     1 
ATOM   9529  C CB    . GLU E 2 126 ? 118.599 165.871 153.368 1.00 85.89  ? 108 GLU F CB    1 
ATOM   9530  C CG    . GLU E 2 126 ? 119.446 167.183 153.345 1.00 85.89  ? 108 GLU F CG    1 
ATOM   9531  C CD    . GLU E 2 126 ? 118.708 168.422 152.835 1.00 85.89  ? 108 GLU F CD    1 
ATOM   9532  O OE1   . GLU E 2 126 ? 117.640 168.295 152.199 1.00 85.89  ? 108 GLU F OE1   1 
ATOM   9533  O OE2   . GLU E 2 126 ? 119.206 169.540 153.083 1.00 85.89  ? 108 GLU F OE2   1 
ATOM   9534  N N     . MET E 2 127 ? 118.949 166.400 156.642 1.00 83.49  ? 109 MET F N     1 
ATOM   9535  C CA    . MET E 2 127 ? 119.865 166.316 157.778 1.00 83.49  ? 109 MET F CA    1 
ATOM   9536  C C     . MET E 2 127 ? 119.082 165.979 159.044 1.00 83.49  ? 109 MET F C     1 
ATOM   9537  O O     . MET E 2 127 ? 117.864 166.154 159.118 1.00 83.49  ? 109 MET F O     1 
ATOM   9538  C CB    . MET E 2 127 ? 120.672 167.613 158.002 1.00 83.49  ? 109 MET F CB    1 
ATOM   9539  C CG    . MET E 2 127 ? 120.059 168.946 157.566 1.00 83.49  ? 109 MET F CG    1 
ATOM   9540  S SD    . MET E 2 127 ? 120.968 170.370 158.189 1.00 83.49  ? 109 MET F SD    1 
ATOM   9541  C CE    . MET E 2 127 ? 119.981 171.709 157.529 1.00 83.49  ? 109 MET F CE    1 
ATOM   9542  N N     . SER E 2 128 ? 119.805 165.482 160.045 1.00 77.93  ? 110 SER F N     1 
ATOM   9543  C CA    . SER E 2 128 ? 119.191 165.089 161.302 1.00 77.93  ? 110 SER F CA    1 
ATOM   9544  C C     . SER E 2 128 ? 118.649 166.314 162.040 1.00 77.93  ? 110 SER F C     1 
ATOM   9545  O O     . SER E 2 128 ? 118.963 167.463 161.715 1.00 77.93  ? 110 SER F O     1 
ATOM   9546  C CB    . SER E 2 128 ? 120.199 164.348 162.178 1.00 77.93  ? 110 SER F CB    1 
ATOM   9547  O OG    . SER E 2 128 ? 121.274 165.196 162.545 1.00 77.93  ? 110 SER F OG    1 
ATOM   9548  N N     . LYS E 2 129 ? 117.806 166.048 163.043 1.00 68.94  ? 111 LYS F N     1 
ATOM   9549  C CA    . LYS E 2 129 ? 117.208 167.130 163.820 1.00 68.94  ? 111 LYS F CA    1 
ATOM   9550  C C     . LYS E 2 129 ? 118.268 167.910 164.591 1.00 68.94  ? 111 LYS F C     1 
ATOM   9551  O O     . LYS E 2 129 ? 118.225 169.148 164.645 1.00 68.94  ? 111 LYS F O     1 
ATOM   9552  C CB    . LYS E 2 129 ? 116.137 166.562 164.762 1.00 68.94  ? 111 LYS F CB    1 
ATOM   9553  C CG    . LYS E 2 129 ? 116.652 165.628 165.866 1.00 68.94  ? 111 LYS F CG    1 
ATOM   9554  C CD    . LYS E 2 129 ? 115.527 164.923 166.609 1.00 68.94  ? 111 LYS F CD    1 
ATOM   9555  C CE    . LYS E 2 129 ? 114.970 163.736 165.834 1.00 68.94  ? 111 LYS F CE    1 
ATOM   9556  N NZ    . LYS E 2 129 ? 114.078 162.899 166.683 1.00 68.94  ? 111 LYS F NZ    1 
ATOM   9557  N N     . THR E 2 130 ? 119.241 167.204 165.175 1.00 71.92  ? 112 THR F N     1 
ATOM   9558  C CA    . THR E 2 130 ? 120.273 167.869 165.962 1.00 71.92  ? 112 THR F CA    1 
ATOM   9559  C C     . THR E 2 130 ? 121.165 168.733 165.079 1.00 71.92  ? 112 THR F C     1 
ATOM   9560  O O     . THR E 2 130 ? 121.580 169.820 165.490 1.00 71.92  ? 112 THR F O     1 
ATOM   9561  C CB    . THR E 2 130 ? 121.102 166.841 166.746 1.00 71.92  ? 112 THR F CB    1 
ATOM   9562  O OG1   . THR E 2 130 ? 122.048 167.526 167.575 1.00 71.92  ? 112 THR F OG1   1 
ATOM   9563  C CG2   . THR E 2 130 ? 121.868 165.864 165.830 1.00 71.92  ? 112 THR F CG2   1 
ATOM   9564  N N     . GLU E 2 131 ? 121.453 168.277 163.857 1.00 78.15  ? 113 GLU F N     1 
ATOM   9565  C CA    . GLU E 2 131 ? 122.286 169.068 162.955 1.00 78.15  ? 113 GLU F CA    1 
ATOM   9566  C C     . GLU E 2 131 ? 121.575 170.345 162.529 1.00 78.15  ? 113 GLU F C     1 
ATOM   9567  O O     . GLU E 2 131 ? 122.193 171.415 162.475 1.00 78.15  ? 113 GLU F O     1 
ATOM   9568  C CB    . GLU E 2 131 ? 122.673 168.240 161.727 1.00 78.15  ? 113 GLU F CB    1 
ATOM   9569  C CG    . GLU E 2 131 ? 123.926 167.380 161.899 1.00 78.15  ? 113 GLU F CG    1 
ATOM   9570  C CD    . GLU E 2 131 ? 125.208 168.190 161.999 1.00 78.15  ? 113 GLU F CD    1 
ATOM   9571  O OE1   . GLU E 2 131 ? 125.332 169.209 161.288 1.00 78.15  ? 113 GLU F OE1   1 
ATOM   9572  O OE2   . GLU E 2 131 ? 126.091 167.807 162.796 1.00 78.15  ? 113 GLU F OE2   1 
ATOM   9573  N N     . ALA E 2 132 ? 120.278 170.253 162.228 1.00 70.64  ? 114 ALA F N     1 
ATOM   9574  C CA    . ALA E 2 132 ? 119.517 171.442 161.861 1.00 70.64  ? 114 ALA F CA    1 
ATOM   9575  C C     . ALA E 2 132 ? 119.430 172.419 163.024 1.00 70.64  ? 114 ALA F C     1 
ATOM   9576  O O     . ALA E 2 132 ? 119.578 173.635 162.837 1.00 70.64  ? 114 ALA F O     1 
ATOM   9577  C CB    . ALA E 2 132 ? 118.119 171.045 161.391 1.00 70.64  ? 114 ALA F CB    1 
ATOM   9578  N N     . LEU E 2 133 ? 119.195 171.906 164.236 1.00 63.59  ? 115 LEU F N     1 
ATOM   9579  C CA    . LEU E 2 133 ? 119.131 172.782 165.402 1.00 63.59  ? 115 LEU F CA    1 
ATOM   9580  C C     . LEU E 2 133 ? 120.478 173.439 165.678 1.00 63.59  ? 115 LEU F C     1 
ATOM   9581  O O     . LEU E 2 133 ? 120.532 174.626 166.016 1.00 63.59  ? 115 LEU F O     1 
ATOM   9582  C CB    . LEU E 2 133 ? 118.650 171.999 166.622 1.00 63.59  ? 115 LEU F CB    1 
ATOM   9583  C CG    . LEU E 2 133 ? 117.169 171.614 166.605 1.00 63.59  ? 115 LEU F CG    1 
ATOM   9584  C CD1   . LEU E 2 133 ? 116.917 170.436 167.523 1.00 63.59  ? 115 LEU F CD1   1 
ATOM   9585  C CD2   . LEU E 2 133 ? 116.292 172.792 167.003 1.00 63.59  ? 115 LEU F CD2   1 
ATOM   9586  N N     . THR E 2 134 ? 121.576 172.692 165.521 1.00 68.73  ? 116 THR F N     1 
ATOM   9587  C CA    . THR E 2 134 ? 122.903 173.265 165.720 1.00 68.73  ? 116 THR F CA    1 
ATOM   9588  C C     . THR E 2 134 ? 123.196 174.342 164.686 1.00 68.73  ? 116 THR F C     1 
ATOM   9589  O O     . THR E 2 134 ? 123.748 175.399 165.018 1.00 68.73  ? 116 THR F O     1 
ATOM   9590  C CB    . THR E 2 134 ? 123.968 172.170 165.648 1.00 68.73  ? 116 THR F CB    1 
ATOM   9591  O OG1   . THR E 2 134 ? 123.541 171.025 166.394 1.00 68.73  ? 116 THR F OG1   1 
ATOM   9592  C CG2   . THR E 2 134 ? 125.296 172.665 166.213 1.00 68.73  ? 116 THR F CG2   1 
ATOM   9593  N N     . GLN E 2 135 ? 122.841 174.089 163.424 1.00 71.37  ? 117 GLN F N     1 
ATOM   9594  C CA    . GLN E 2 135 ? 123.089 175.069 162.374 1.00 71.37  ? 117 GLN F CA    1 
ATOM   9595  C C     . GLN E 2 135 ? 122.271 176.334 162.592 1.00 71.37  ? 117 GLN F C     1 
ATOM   9596  O O     . GLN E 2 135 ? 122.776 177.445 162.395 1.00 71.37  ? 117 GLN F O     1 
ATOM   9597  C CB    . GLN E 2 135 ? 122.786 174.459 161.007 1.00 71.37  ? 117 GLN F CB    1 
ATOM   9598  C CG    . GLN E 2 135 ? 123.862 173.492 160.523 1.00 71.37  ? 117 GLN F CG    1 
ATOM   9599  C CD    . GLN E 2 135 ? 123.486 172.747 159.252 1.00 71.37  ? 117 GLN F CD    1 
ATOM   9600  O OE1   . GLN E 2 135 ? 123.716 171.543 159.147 1.00 71.37  ? 117 GLN F OE1   1 
ATOM   9601  N NE2   . GLN E 2 135 ? 122.934 173.457 158.272 1.00 71.37  ? 117 GLN F NE2   1 
ATOM   9602  N N     . SER E 2 136 ? 121.011 176.194 163.007 1.00 64.13  ? 118 SER F N     1 
ATOM   9603  C CA    . SER E 2 136 ? 120.203 177.379 163.273 1.00 64.13  ? 118 SER F CA    1 
ATOM   9604  C C     . SER E 2 136 ? 120.699 178.129 164.505 1.00 64.13  ? 118 SER F C     1 
ATOM   9605  O O     . SER E 2 136 ? 120.650 179.364 164.542 1.00 64.13  ? 118 SER F O     1 
ATOM   9606  C CB    . SER E 2 136 ? 118.737 176.990 163.433 1.00 64.13  ? 118 SER F CB    1 
ATOM   9607  O OG    . SER E 2 136 ? 118.602 175.785 164.162 1.00 64.13  ? 118 SER F OG    1 
ATOM   9608  N N     . PHE E 2 137 ? 121.164 177.403 165.527 1.00 61.30  ? 119 PHE F N     1 
ATOM   9609  C CA    . PHE E 2 137 ? 121.718 178.061 166.709 1.00 61.30  ? 119 PHE F CA    1 
ATOM   9610  C C     . PHE E 2 137 ? 122.971 178.850 166.357 1.00 61.30  ? 119 PHE F C     1 
ATOM   9611  O O     . PHE E 2 137 ? 123.151 179.983 166.817 1.00 61.30  ? 119 PHE F O     1 
ATOM   9612  C CB    . PHE E 2 137 ? 122.032 177.039 167.806 1.00 61.30  ? 119 PHE F CB    1 
ATOM   9613  C CG    . PHE E 2 137 ? 121.030 177.025 168.922 1.00 61.30  ? 119 PHE F CG    1 
ATOM   9614  C CD1   . PHE E 2 137 ? 121.188 177.853 170.018 1.00 61.30  ? 119 PHE F CD1   1 
ATOM   9615  C CD2   . PHE E 2 137 ? 119.934 176.181 168.877 1.00 61.30  ? 119 PHE F CD2   1 
ATOM   9616  C CE1   . PHE E 2 137 ? 120.269 177.845 171.046 1.00 61.30  ? 119 PHE F CE1   1 
ATOM   9617  C CE2   . PHE E 2 137 ? 119.012 176.168 169.904 1.00 61.30  ? 119 PHE F CE2   1 
ATOM   9618  C CZ    . PHE E 2 137 ? 119.180 177.002 170.989 1.00 61.30  ? 119 PHE F CZ    1 
ATOM   9619  N N     . ARG E 2 138 ? 123.848 178.269 165.538 1.00 71.17  ? 120 ARG F N     1 
ATOM   9620  C CA    . ARG E 2 138 ? 125.020 178.996 165.070 1.00 71.17  ? 120 ARG F CA    1 
ATOM   9621  C C     . ARG E 2 138 ? 124.657 180.117 164.103 1.00 71.17  ? 120 ARG F C     1 
ATOM   9622  O O     . ARG E 2 138 ? 125.438 181.062 163.950 1.00 71.17  ? 120 ARG F O     1 
ATOM   9623  C CB    . ARG E 2 138 ? 126.002 178.028 164.410 1.00 71.17  ? 120 ARG F CB    1 
ATOM   9624  C CG    . ARG E 2 138 ? 126.634 177.047 165.385 1.00 71.17  ? 120 ARG F CG    1 
ATOM   9625  C CD    . ARG E 2 138 ? 127.696 176.189 164.716 1.00 71.17  ? 120 ARG F CD    1 
ATOM   9626  N NE    . ARG E 2 138 ? 128.913 176.939 164.421 1.00 71.17  ? 120 ARG F NE    1 
ATOM   9627  C CZ    . ARG E 2 138 ? 129.803 177.352 165.317 1.00 71.17  ? 120 ARG F CZ    1 
ATOM   9628  N NH1   . ARG E 2 138 ? 129.661 177.116 166.615 1.00 71.17  ? 120 ARG F NH1   1 
ATOM   9629  N NH2   . ARG E 2 138 ? 130.874 178.021 164.901 1.00 71.17  ? 120 ARG F NH2   1 
ATOM   9630  N N     . LYS E 2 139 ? 123.497 180.032 163.447 1.00 65.31  ? 121 LYS F N     1 
ATOM   9631  C CA    . LYS E 2 139 ? 123.070 181.092 162.539 1.00 65.31  ? 121 LYS F CA    1 
ATOM   9632  C C     . LYS E 2 139 ? 122.807 182.402 163.275 1.00 65.31  ? 121 LYS F C     1 
ATOM   9633  O O     . LYS E 2 139 ? 122.999 183.479 162.700 1.00 65.31  ? 121 LYS F O     1 
ATOM   9634  C CB    . LYS E 2 139 ? 121.813 180.646 161.790 1.00 65.31  ? 121 LYS F CB    1 
ATOM   9635  C CG    . LYS E 2 139 ? 121.498 181.436 160.523 1.00 65.31  ? 121 LYS F CG    1 
ATOM   9636  C CD    . LYS E 2 139 ? 122.198 180.863 159.295 1.00 65.31  ? 121 LYS F CD    1 
ATOM   9637  C CE    . LYS E 2 139 ? 121.491 179.631 158.737 1.00 65.31  ? 121 LYS F CE    1 
ATOM   9638  N NZ    . LYS E 2 139 ? 121.998 179.273 157.385 1.00 65.31  ? 121 LYS F NZ    1 
ATOM   9639  N N     . ALA E 2 140 ? 122.376 182.335 164.536 1.00 60.68  ? 122 ALA F N     1 
ATOM   9640  C CA    . ALA E 2 140 ? 121.906 183.493 165.296 1.00 60.68  ? 122 ALA F CA    1 
ATOM   9641  C C     . ALA E 2 140 ? 122.973 184.051 166.230 1.00 60.68  ? 122 ALA F C     1 
ATOM   9642  O O     . ALA E 2 140 ? 122.656 184.483 167.342 1.00 60.68  ? 122 ALA F O     1 
ATOM   9643  C CB    . ALA E 2 140 ? 120.654 183.122 166.084 1.00 60.68  ? 122 ALA F CB    1 
ATOM   9644  N N     . ILE E 2 141 ? 124.240 184.039 165.814 1.00 68.11  ? 123 ILE F N     1 
ATOM   9645  C CA    . ILE E 2 141 ? 125.358 184.593 166.584 1.00 68.11  ? 123 ILE F CA    1 
ATOM   9646  C C     . ILE E 2 141 ? 126.186 185.405 165.596 1.00 68.11  ? 123 ILE F C     1 
ATOM   9647  O O     . ILE E 2 141 ? 126.999 184.844 164.853 1.00 68.11  ? 123 ILE F O     1 
ATOM   9648  C CB    . ILE E 2 141 ? 126.217 183.513 167.268 1.00 68.11  ? 123 ILE F CB    1 
ATOM   9649  C CG1   . ILE E 2 141 ? 125.374 182.585 168.173 1.00 68.11  ? 123 ILE F CG1   1 
ATOM   9650  C CG2   . ILE E 2 141 ? 127.380 184.185 168.036 1.00 68.11  ? 123 ILE F CG2   1 
ATOM   9651  C CD1   . ILE E 2 141 ? 126.091 181.319 168.637 1.00 68.11  ? 123 ILE F CD1   1 
ATOM   9652  N N     . GLY E 2 142 ? 126.001 186.726 165.594 1.00 74.54  ? 124 GLY F N     1 
ATOM   9653  C CA    . GLY E 2 142 ? 126.589 187.563 164.564 1.00 74.54  ? 124 GLY F CA    1 
ATOM   9654  C C     . GLY E 2 142 ? 127.972 188.076 164.906 1.00 74.54  ? 124 GLY F C     1 
ATOM   9655  O O     . GLY E 2 142 ? 128.142 188.781 165.905 1.00 74.54  ? 124 GLY F O     1 
ATOM   9656  N N     . VAL E 2 143 ? 128.960 187.742 164.075 1.00 82.62  ? 125 VAL F N     1 
ATOM   9657  C CA    . VAL E 2 143 ? 130.338 188.197 164.241 1.00 82.62  ? 125 VAL F CA    1 
ATOM   9658  C C     . VAL E 2 143 ? 130.538 189.398 163.326 1.00 82.62  ? 125 VAL F C     1 
ATOM   9659  O O     . VAL E 2 143 ? 130.397 189.284 162.102 1.00 82.62  ? 125 VAL F O     1 
ATOM   9660  C CB    . VAL E 2 143 ? 131.347 187.081 163.920 1.00 82.62  ? 125 VAL F CB    1 
ATOM   9661  C CG1   . VAL E 2 143 ? 132.752 187.464 164.397 1.00 82.62  ? 125 VAL F CG1   1 
ATOM   9662  C CG2   . VAL E 2 143 ? 130.894 185.757 164.531 1.00 82.62  ? 125 VAL F CG2   1 
ATOM   9663  N N     . ARG E 2 144 ? 130.864 190.542 163.923 1.00 88.76  ? 126 ARG F N     1 
ATOM   9664  C CA    . ARG E 2 144 ? 131.087 191.799 163.211 1.00 88.76  ? 126 ARG F CA    1 
ATOM   9665  C C     . ARG E 2 144 ? 132.477 192.351 163.517 1.00 88.76  ? 126 ARG F C     1 
ATOM   9666  O O     . ARG E 2 144 ? 132.998 192.170 164.617 1.00 88.76  ? 126 ARG F O     1 
ATOM   9667  C CB    . ARG E 2 144 ? 130.010 192.819 163.590 1.00 88.76  ? 126 ARG F CB    1 
ATOM   9668  C CG    . ARG E 2 144 ? 130.192 193.462 164.961 1.00 88.76  ? 126 ARG F CG    1 
ATOM   9669  C CD    . ARG E 2 144 ? 128.856 193.830 165.581 1.00 88.76  ? 126 ARG F CD    1 
ATOM   9670  N NE    . ARG E 2 144 ? 129.021 194.645 166.781 1.00 88.76  ? 126 ARG F NE    1 
ATOM   9671  C CZ    . ARG E 2 144 ? 128.041 195.252 167.443 1.00 88.76  ? 126 ARG F CZ    1 
ATOM   9672  N NH1   . ARG E 2 144 ? 126.773 195.165 167.062 1.00 88.76  ? 126 ARG F NH1   1 
ATOM   9673  N NH2   . ARG E 2 144 ? 128.341 195.970 168.521 1.00 88.76  ? 126 ARG F NH2   1 
ATOM   9674  N N     . CYS E 2 256 ? 128.537 192.164 158.425 1.00 87.41  ? 238 CYS F N     1 
ATOM   9675  C CA    . CYS E 2 256 ? 128.490 191.148 159.514 1.00 87.41  ? 238 CYS F CA    1 
ATOM   9676  C C     . CYS E 2 256 ? 128.432 189.737 158.939 1.00 87.41  ? 238 CYS F C     1 
ATOM   9677  O O     . CYS E 2 256 ? 127.875 189.521 157.862 1.00 87.41  ? 238 CYS F O     1 
ATOM   9678  C CB    . CYS E 2 256 ? 127.285 191.392 160.425 1.00 87.41  ? 238 CYS F CB    1 
ATOM   9679  S SG    . CYS E 2 256 ? 126.941 190.044 161.582 1.00 87.41  ? 238 CYS F SG    1 
ATOM   9680  N N     . VAL E 2 257 ? 129.022 188.791 159.668 1.00 78.02  ? 239 VAL F N     1 
ATOM   9681  C CA    . VAL E 2 257 ? 129.027 187.377 159.307 1.00 78.02  ? 239 VAL F CA    1 
ATOM   9682  C C     . VAL E 2 257 ? 128.736 186.569 160.564 1.00 78.02  ? 239 VAL F C     1 
ATOM   9683  O O     . VAL E 2 257 ? 129.253 186.875 161.643 1.00 78.02  ? 239 VAL F O     1 
ATOM   9684  C CB    . VAL E 2 257 ? 130.369 186.949 158.666 1.00 78.02  ? 239 VAL F CB    1 
ATOM   9685  C CG1   . VAL E 2 257 ? 131.531 187.025 159.672 1.00 78.02  ? 239 VAL F CG1   1 
ATOM   9686  C CG2   . VAL E 2 257 ? 130.260 185.551 158.058 1.00 78.02  ? 239 VAL F CG2   1 
ATOM   9687  N N     . THR E 2 258 ? 127.893 185.551 160.427 1.00 72.83  ? 240 THR F N     1 
ATOM   9688  C CA    . THR E 2 258 ? 127.517 184.692 161.539 1.00 72.83  ? 240 THR F CA    1 
ATOM   9689  C C     . THR E 2 258 ? 128.482 183.513 161.643 1.00 72.83  ? 240 THR F C     1 
ATOM   9690  O O     . THR E 2 258 ? 129.296 183.260 160.754 1.00 72.83  ? 240 THR F O     1 
ATOM   9691  C CB    . THR E 2 258 ? 126.085 184.192 161.368 1.00 72.83  ? 240 THR F CB    1 
ATOM   9692  O OG1   . THR E 2 258 ? 126.043 183.211 160.328 1.00 72.83  ? 240 THR F OG1   1 
ATOM   9693  C CG2   . THR E 2 258 ? 125.159 185.348 160.999 1.00 72.83  ? 240 THR F CG2   1 
ATOM   9694  N N     . LEU E 2 259 ? 128.384 182.786 162.758 1.00 74.69  ? 241 LEU F N     1 
ATOM   9695  C CA    . LEU E 2 259 ? 129.232 181.612 162.948 1.00 74.69  ? 241 LEU F CA    1 
ATOM   9696  C C     . LEU E 2 259 ? 128.883 180.513 161.950 1.00 74.69  ? 241 LEU F C     1 
ATOM   9697  O O     . LEU E 2 259 ? 129.770 179.796 161.467 1.00 74.69  ? 241 LEU F O     1 
ATOM   9698  C CB    . LEU E 2 259 ? 129.100 181.096 164.387 1.00 74.69  ? 241 LEU F CB    1 
ATOM   9699  C CG    . LEU E 2 259 ? 129.976 181.683 165.505 1.00 74.69  ? 241 LEU F CG    1 
ATOM   9700  C CD1   . LEU E 2 259 ? 129.655 180.960 166.802 1.00 74.69  ? 241 LEU F CD1   1 
ATOM   9701  C CD2   . LEU E 2 259 ? 131.475 181.591 165.221 1.00 74.69  ? 241 LEU F CD2   1 
ATOM   9702  N N     . HIS E 2 260 ? 127.598 180.365 161.623 1.00 68.28  ? 242 HIS F N     1 
ATOM   9703  C CA    . HIS E 2 260 ? 127.209 179.363 160.635 1.00 68.28  ? 242 HIS F CA    1 
ATOM   9704  C C     . HIS E 2 260 ? 127.742 179.699 159.250 1.00 68.28  ? 242 HIS F C     1 
ATOM   9705  O O     . HIS E 2 260 ? 128.084 178.792 158.477 1.00 68.28  ? 242 HIS F O     1 
ATOM   9706  C CB    . HIS E 2 260 ? 125.694 179.232 160.573 1.00 68.28  ? 242 HIS F CB    1 
ATOM   9707  C CG    . HIS E 2 260 ? 125.234 178.152 159.652 1.00 68.28  ? 242 HIS F CG    1 
ATOM   9708  N ND1   . HIS E 2 260 ? 124.833 178.402 158.359 1.00 68.28  ? 242 HIS F ND1   1 
ATOM   9709  C CD2   . HIS E 2 260 ? 125.116 176.817 159.834 1.00 68.28  ? 242 HIS F CD2   1 
ATOM   9710  C CE1   . HIS E 2 260 ? 124.486 177.266 157.783 1.00 68.28  ? 242 HIS F CE1   1 
ATOM   9711  N NE2   . HIS E 2 260 ? 124.646 176.289 158.657 1.00 68.28  ? 242 HIS F NE2   1 
ATOM   9712  N N     . GLU E 2 261 ? 127.806 180.987 158.910 1.00 72.07  ? 243 GLU F N     1 
ATOM   9713  C CA    . GLU E 2 261 ? 128.402 181.379 157.639 1.00 72.07  ? 243 GLU F CA    1 
ATOM   9714  C C     . GLU E 2 261 ? 129.889 181.053 157.619 1.00 72.07  ? 243 GLU F C     1 
ATOM   9715  O O     . GLU E 2 261 ? 130.433 180.655 156.582 1.00 72.07  ? 243 GLU F O     1 
ATOM   9716  C CB    . GLU E 2 261 ? 128.167 182.867 157.387 1.00 72.07  ? 243 GLU F CB    1 
ATOM   9717  C CG    . GLU E 2 261 ? 126.702 183.246 157.177 1.00 72.07  ? 243 GLU F CG    1 
ATOM   9718  C CD    . GLU E 2 261 ? 126.192 182.922 155.787 1.00 72.07  ? 243 GLU F CD    1 
ATOM   9719  O OE1   . GLU E 2 261 ? 126.893 182.209 155.039 1.00 72.07  ? 243 GLU F OE1   1 
ATOM   9720  O OE2   . GLU E 2 261 ? 125.079 183.376 155.446 1.00 72.07  ? 243 GLU F OE2   1 
ATOM   9721  N N     . ILE E 2 262 ? 130.558 181.197 158.767 1.00 71.41  ? 244 ILE F N     1 
ATOM   9722  C CA    . ILE E 2 262 ? 131.958 180.795 158.871 1.00 71.41  ? 244 ILE F CA    1 
ATOM   9723  C C     . ILE E 2 262 ? 132.084 179.290 158.671 1.00 71.41  ? 244 ILE F C     1 
ATOM   9724  O O     . ILE E 2 262 ? 133.055 178.808 158.076 1.00 71.41  ? 244 ILE F O     1 
ATOM   9725  C CB    . ILE E 2 262 ? 132.548 181.248 160.224 1.00 71.41  ? 244 ILE F CB    1 
ATOM   9726  C CG1   . ILE E 2 262 ? 132.757 182.768 160.232 1.00 71.41  ? 244 ILE F CG1   1 
ATOM   9727  C CG2   . ILE E 2 262 ? 133.893 180.543 160.523 1.00 71.41  ? 244 ILE F CG2   1 
ATOM   9728  C CD1   . ILE E 2 262 ? 132.851 183.385 161.622 1.00 71.41  ? 244 ILE F CD1   1 
ATOM   9729  N N     . ASP E 2 263 ? 131.113 178.523 159.175 1.00 71.64  ? 245 ASP F N     1 
ATOM   9730  C CA    . ASP E 2 263 ? 131.160 177.074 159.000 1.00 71.64  ? 245 ASP F CA    1 
ATOM   9731  C C     . ASP E 2 263 ? 130.982 176.713 157.526 1.00 71.64  ? 245 ASP F C     1 
ATOM   9732  O O     . ASP E 2 263 ? 131.642 175.796 157.025 1.00 71.64  ? 245 ASP F O     1 
ATOM   9733  C CB    . ASP E 2 263 ? 130.086 176.416 159.880 1.00 71.64  ? 245 ASP F CB    1 
ATOM   9734  C CG    . ASP E 2 263 ? 130.103 174.872 159.851 1.00 71.64  ? 245 ASP F CG    1 
ATOM   9735  O OD1   . ASP E 2 263 ? 130.810 174.221 159.054 1.00 71.64  ? 245 ASP F OD1   1 
ATOM   9736  O OD2   . ASP E 2 263 ? 129.412 174.289 160.712 1.00 71.64  ? 245 ASP F OD2   1 
ATOM   9737  N N     . VAL E 2 264 ? 130.099 177.422 156.816 1.00 68.49  ? 246 VAL F N     1 
ATOM   9738  C CA    . VAL E 2 264 ? 129.914 177.131 155.391 1.00 68.49  ? 246 VAL F CA    1 
ATOM   9739  C C     . VAL E 2 264 ? 131.160 177.532 154.606 1.00 68.49  ? 246 VAL F C     1 
ATOM   9740  O O     . VAL E 2 264 ? 131.534 176.861 153.638 1.00 68.49  ? 246 VAL F O     1 
ATOM   9741  C CB    . VAL E 2 264 ? 128.644 177.802 154.811 1.00 68.49  ? 246 VAL F CB    1 
ATOM   9742  C CG1   . VAL E 2 264 ? 128.283 177.204 153.436 1.00 68.49  ? 246 VAL F CG1   1 
ATOM   9743  C CG2   . VAL E 2 264 ? 127.402 177.653 155.725 1.00 68.49  ? 246 VAL F CG2   1 
ATOM   9744  N N     . ILE E 2 265 ? 131.804 178.641 154.986 1.00 68.37  ? 247 ILE F N     1 
ATOM   9745  C CA    . ILE E 2 265 ? 133.032 179.051 154.305 1.00 68.37  ? 247 ILE F CA    1 
ATOM   9746  C C     . ILE E 2 265 ? 134.138 178.026 154.545 1.00 68.37  ? 247 ILE F C     1 
ATOM   9747  O O     . ILE E 2 265 ? 134.876 177.663 153.621 1.00 68.37  ? 247 ILE F O     1 
ATOM   9748  C CB    . ILE E 2 265 ? 133.434 180.473 154.755 1.00 68.37  ? 247 ILE F CB    1 
ATOM   9749  C CG1   . ILE E 2 265 ? 132.577 181.503 154.012 1.00 68.37  ? 247 ILE F CG1   1 
ATOM   9750  C CG2   . ILE E 2 265 ? 134.928 180.782 154.480 1.00 68.37  ? 247 ILE F CG2   1 
ATOM   9751  C CD1   . ILE E 2 265 ? 132.458 182.847 154.713 1.00 68.37  ? 247 ILE F CD1   1 
ATOM   9752  N N     . ASN E 2 266 ? 134.267 177.538 155.779 1.00 66.09  ? 248 ASN F N     1 
ATOM   9753  C CA    . ASN E 2 266 ? 135.291 176.554 156.111 1.00 66.09  ? 248 ASN F CA    1 
ATOM   9754  C C     . ASN E 2 266 ? 134.950 175.140 155.646 1.00 66.09  ? 248 ASN F C     1 
ATOM   9755  O O     . ASN E 2 266 ? 135.802 174.253 155.763 1.00 66.09  ? 248 ASN F O     1 
ATOM   9756  C CB    . ASN E 2 266 ? 135.543 176.543 157.623 1.00 66.09  ? 248 ASN F CB    1 
ATOM   9757  C CG    . ASN E 2 266 ? 136.579 177.565 158.046 1.00 66.09  ? 248 ASN F CG    1 
ATOM   9758  O OD1   . ASN E 2 266 ? 137.640 177.214 158.560 1.00 66.09  ? 248 ASN F OD1   1 
ATOM   9759  N ND2   . ASN E 2 266 ? 136.278 178.838 157.822 1.00 66.09  ? 248 ASN F ND2   1 
ATOM   9760  N N     . SER E 2 267 ? 133.743 174.899 155.138 1.00 67.94  ? 249 SER F N     1 
ATOM   9761  C CA    . SER E 2 267 ? 133.379 173.583 154.622 1.00 67.94  ? 249 SER F CA    1 
ATOM   9762  C C     . SER E 2 267 ? 134.218 173.227 153.399 1.00 67.94  ? 249 SER F C     1 
ATOM   9763  O O     . SER E 2 267 ? 134.001 172.196 152.764 1.00 67.94  ? 249 SER F O     1 
ATOM   9764  C CB    . SER E 2 267 ? 131.893 173.540 154.264 1.00 67.94  ? 249 SER F CB    1 
ATOM   9765  O OG    . SER E 2 267 ? 131.619 174.357 153.138 1.00 67.94  ? 249 SER F OG    1 
ATOM   9766  N N     . THR E 2 280 ? 125.733 170.131 154.383 1.00 98.86  ? 262 THR F N     1 
ATOM   9767  C CA    . THR E 2 280 ? 125.909 169.957 155.853 1.00 98.86  ? 262 THR F CA    1 
ATOM   9768  C C     . THR E 2 280 ? 127.272 169.341 156.153 1.00 98.86  ? 262 THR F C     1 
ATOM   9769  O O     . THR E 2 280 ? 128.132 169.981 156.758 1.00 98.86  ? 262 THR F O     1 
ATOM   9770  C CB    . THR E 2 280 ? 124.793 169.069 156.452 1.00 98.86  ? 262 THR F CB    1 
ATOM   9771  O OG1   . THR E 2 280 ? 123.532 169.738 156.332 1.00 98.86  ? 262 THR F OG1   1 
ATOM   9772  C CG2   . THR E 2 280 ? 125.058 168.765 157.926 1.00 98.86  ? 262 THR F CG2   1 
ATOM   9773  N N     . GLY E 2 281 ? 127.462 168.096 155.725 1.00 105.03 ? 263 GLY F N     1 
ATOM   9774  C CA    . GLY E 2 281 ? 128.692 167.381 156.003 1.00 105.03 ? 263 GLY F CA    1 
ATOM   9775  C C     . GLY E 2 281 ? 128.881 167.121 157.483 1.00 105.03 ? 263 GLY F C     1 
ATOM   9776  O O     . GLY E 2 281 ? 128.148 166.324 158.076 1.00 105.03 ? 263 GLY F O     1 
ATOM   9777  N N     . GLU E 2 282 ? 129.873 167.785 158.080 1.00 99.55  ? 264 GLU F N     1 
ATOM   9778  C CA    . GLU E 2 282 ? 130.151 167.699 159.508 1.00 99.55  ? 264 GLU F CA    1 
ATOM   9779  C C     . GLU E 2 282 ? 130.493 169.088 160.026 1.00 99.55  ? 264 GLU F C     1 
ATOM   9780  O O     . GLU E 2 282 ? 130.980 169.941 159.280 1.00 99.55  ? 264 GLU F O     1 
ATOM   9781  C CB    . GLU E 2 282 ? 131.312 166.735 159.814 1.00 99.55  ? 264 GLU F CB    1 
ATOM   9782  C CG    . GLU E 2 282 ? 131.111 165.292 159.344 1.00 99.55  ? 264 GLU F CG    1 
ATOM   9783  C CD    . GLU E 2 282 ? 130.080 164.530 160.160 1.00 99.55  ? 264 GLU F CD    1 
ATOM   9784  O OE1   . GLU E 2 282 ? 129.492 165.116 161.093 1.00 99.55  ? 264 GLU F OE1   1 
ATOM   9785  O OE2   . GLU E 2 282 ? 129.859 163.337 159.866 1.00 99.55  ? 264 GLU F OE2   1 
ATOM   9786  N N     . ILE E 2 283 ? 130.232 169.301 161.315 1.00 87.10  ? 265 ILE F N     1 
ATOM   9787  C CA    . ILE E 2 283 ? 130.523 170.559 161.999 1.00 87.10  ? 265 ILE F CA    1 
ATOM   9788  C C     . ILE E 2 283 ? 131.858 170.392 162.715 1.00 87.10  ? 265 ILE F C     1 
ATOM   9789  O O     . ILE E 2 283 ? 132.027 169.471 163.523 1.00 87.10  ? 265 ILE F O     1 
ATOM   9790  C CB    . ILE E 2 283 ? 129.398 170.943 162.979 1.00 87.10  ? 265 ILE F CB    1 
ATOM   9791  C CG1   . ILE E 2 283 ? 128.139 171.369 162.209 1.00 87.10  ? 265 ILE F CG1   1 
ATOM   9792  C CG2   . ILE E 2 283 ? 129.847 172.087 163.916 1.00 87.10  ? 265 ILE F CG2   1 
ATOM   9793  C CD1   . ILE E 2 283 ? 126.852 171.319 163.018 1.00 87.10  ? 265 ILE F CD1   1 
ATOM   9794  N N     . ARG E 2 284 ? 132.801 171.284 162.420 1.00 90.92  ? 266 ARG F N     1 
ATOM   9795  C CA    . ARG E 2 284 ? 134.130 171.249 163.016 1.00 90.92  ? 266 ARG F CA    1 
ATOM   9796  C C     . ARG E 2 284 ? 134.121 172.007 164.336 1.00 90.92  ? 266 ARG F C     1 
ATOM   9797  O O     . ARG E 2 284 ? 133.626 173.137 164.408 1.00 90.92  ? 266 ARG F O     1 
ATOM   9798  C CB    . ARG E 2 284 ? 135.162 171.865 162.067 1.00 90.92  ? 266 ARG F CB    1 
ATOM   9799  C CG    . ARG E 2 284 ? 135.146 171.346 160.622 1.00 90.92  ? 266 ARG F CG    1 
ATOM   9800  C CD    . ARG E 2 284 ? 134.923 169.842 160.512 1.00 90.92  ? 266 ARG F CD    1 
ATOM   9801  N NE    . ARG E 2 284 ? 135.378 169.319 159.227 1.00 90.92  ? 266 ARG F NE    1 
ATOM   9802  C CZ    . ARG E 2 284 ? 135.613 168.040 158.950 1.00 90.92  ? 266 ARG F CZ    1 
ATOM   9803  N NH1   . ARG E 2 284 ? 135.439 167.080 159.848 1.00 90.92  ? 266 ARG F NH1   1 
ATOM   9804  N NH2   . ARG E 2 284 ? 136.035 167.712 157.732 1.00 90.92  ? 266 ARG F NH2   1 
ATOM   9805  N N     . SER E 2 285 ? 134.668 171.381 165.378 1.00 93.19  ? 267 SER F N     1 
ATOM   9806  C CA    . SER E 2 285 ? 134.782 172.025 166.682 1.00 93.19  ? 267 SER F CA    1 
ATOM   9807  C C     . SER E 2 285 ? 135.940 173.012 166.771 1.00 93.19  ? 267 SER F C     1 
ATOM   9808  O O     . SER E 2 285 ? 136.031 173.730 167.772 1.00 93.19  ? 267 SER F O     1 
ATOM   9809  C CB    . SER E 2 285 ? 134.946 170.976 167.786 1.00 93.19  ? 267 SER F CB    1 
ATOM   9810  O OG    . SER E 2 285 ? 135.667 171.512 168.881 1.00 93.19  ? 267 SER F OG    1 
ATOM   9811  N N     . GLU E 2 286 ? 136.821 173.070 165.765 1.00 93.40  ? 268 GLU F N     1 
ATOM   9812  C CA    . GLU E 2 286 ? 137.950 173.997 165.813 1.00 93.40  ? 268 GLU F CA    1 
ATOM   9813  C C     . GLU E 2 286 ? 137.498 175.453 165.793 1.00 93.40  ? 268 GLU F C     1 
ATOM   9814  O O     . GLU E 2 286 ? 138.204 176.322 166.326 1.00 93.40  ? 268 GLU F O     1 
ATOM   9815  C CB    . GLU E 2 286 ? 138.900 173.747 164.638 1.00 93.40  ? 268 GLU F CB    1 
ATOM   9816  C CG    . GLU E 2 286 ? 139.368 172.305 164.454 1.00 93.40  ? 268 GLU F CG    1 
ATOM   9817  C CD    . GLU E 2 286 ? 140.354 172.160 163.310 1.00 93.40  ? 268 GLU F CD    1 
ATOM   9818  O OE1   . GLU E 2 286 ? 141.228 173.039 163.160 1.00 93.40  ? 268 GLU F OE1   1 
ATOM   9819  O OE2   . GLU E 2 286 ? 140.248 171.170 162.557 1.00 93.40  ? 268 GLU F OE2   1 
ATOM   9820  N N     . VAL E 2 287 ? 136.331 175.734 165.196 1.00 85.29  ? 269 VAL F N     1 
ATOM   9821  C CA    . VAL E 2 287 ? 135.891 177.114 165.000 1.00 85.29  ? 269 VAL F CA    1 
ATOM   9822  C C     . VAL E 2 287 ? 135.643 177.787 166.339 1.00 85.29  ? 269 VAL F C     1 
ATOM   9823  O O     . VAL E 2 287 ? 135.923 178.979 166.492 1.00 85.29  ? 269 VAL F O     1 
ATOM   9824  C CB    . VAL E 2 287 ? 134.636 177.184 164.100 1.00 85.29  ? 269 VAL F CB    1 
ATOM   9825  C CG1   . VAL E 2 287 ? 134.295 178.648 163.759 1.00 85.29  ? 269 VAL F CG1   1 
ATOM   9826  C CG2   . VAL E 2 287 ? 134.838 176.375 162.801 1.00 85.29  ? 269 VAL F CG2   1 
ATOM   9827  N N     . ARG E 2 288 ? 135.134 177.045 167.328 1.00 85.78  ? 270 ARG F N     1 
ATOM   9828  C CA    . ARG E 2 288 ? 134.898 177.635 168.644 1.00 85.78  ? 270 ARG F CA    1 
ATOM   9829  C C     . ARG E 2 288 ? 136.208 178.042 169.310 1.00 85.78  ? 270 ARG F C     1 
ATOM   9830  O O     . ARG E 2 288 ? 136.298 179.127 169.891 1.00 85.78  ? 270 ARG F O     1 
ATOM   9831  C CB    . ARG E 2 288 ? 134.116 176.667 169.536 1.00 85.78  ? 270 ARG F CB    1 
ATOM   9832  C CG    . ARG E 2 288 ? 132.617 176.938 169.522 1.00 85.78  ? 270 ARG F CG    1 
ATOM   9833  C CD    . ARG E 2 288 ? 131.832 175.999 170.424 1.00 85.78  ? 270 ARG F CD    1 
ATOM   9834  N NE    . ARG E 2 288 ? 130.438 176.438 170.540 1.00 85.78  ? 270 ARG F NE    1 
ATOM   9835  C CZ    . ARG E 2 288 ? 129.360 175.835 170.040 1.00 85.78  ? 270 ARG F CZ    1 
ATOM   9836  N NH1   . ARG E 2 288 ? 129.423 174.672 169.403 1.00 85.78  ? 270 ARG F NH1   1 
ATOM   9837  N NH2   . ARG E 2 288 ? 128.173 176.418 170.184 1.00 85.78  ? 270 ARG F NH2   1 
ATOM   9838  N N     . GLU E 2 289 ? 137.243 177.203 169.214 1.00 93.55  ? 271 GLU F N     1 
ATOM   9839  C CA    . GLU E 2 289 ? 138.543 177.565 169.776 1.00 93.55  ? 271 GLU F CA    1 
ATOM   9840  C C     . GLU E 2 289 ? 139.141 178.771 169.058 1.00 93.55  ? 271 GLU F C     1 
ATOM   9841  O O     . GLU E 2 289 ? 139.644 179.703 169.705 1.00 93.55  ? 271 GLU F O     1 
ATOM   9842  C CB    . GLU E 2 289 ? 139.505 176.373 169.704 1.00 93.55  ? 271 GLU F CB    1 
ATOM   9843  C CG    . GLU E 2 289 ? 139.463 175.431 170.913 1.00 93.55  ? 271 GLU F CG    1 
ATOM   9844  C CD    . GLU E 2 289 ? 138.306 174.448 170.883 1.00 93.55  ? 271 GLU F CD    1 
ATOM   9845  O OE1   . GLU E 2 289 ? 137.510 174.475 169.924 1.00 93.55  ? 271 GLU F OE1   1 
ATOM   9846  O OE2   . GLU E 2 289 ? 138.193 173.644 171.832 1.00 93.55  ? 271 GLU F OE2   1 
ATOM   9847  N N     . GLN E 2 290 ? 139.086 178.773 167.719 1.00 92.98  ? 272 GLN F N     1 
ATOM   9848  C CA    . GLN E 2 290 ? 139.658 179.882 166.957 1.00 92.98  ? 272 GLN F CA    1 
ATOM   9849  C C     . GLN E 2 290 ? 138.944 181.194 167.256 1.00 92.98  ? 272 GLN F C     1 
ATOM   9850  O O     . GLN E 2 290 ? 139.595 182.221 167.485 1.00 92.98  ? 272 GLN F O     1 
ATOM   9851  C CB    . GLN E 2 290 ? 139.602 179.598 165.455 1.00 92.98  ? 272 GLN F CB    1 
ATOM   9852  C CG    . GLN E 2 290 ? 140.255 178.301 165.012 1.00 92.98  ? 272 GLN F CG    1 
ATOM   9853  C CD    . GLN E 2 290 ? 141.191 178.498 163.834 1.00 92.98  ? 272 GLN F CD    1 
ATOM   9854  O OE1   . GLN E 2 290 ? 142.321 178.957 163.998 1.00 92.98  ? 272 GLN F OE1   1 
ATOM   9855  N NE2   . GLN E 2 290 ? 140.724 178.155 162.637 1.00 92.98  ? 272 GLN F NE2   1 
ATOM   9856  N N     . ILE E 2 291 ? 137.610 181.176 167.294 1.00 90.25  ? 273 ILE F N     1 
ATOM   9857  C CA    . ILE E 2 291 ? 136.874 182.417 167.501 1.00 90.25  ? 273 ILE F CA    1 
ATOM   9858  C C     . ILE E 2 291 ? 136.966 182.850 168.962 1.00 90.25  ? 273 ILE F C     1 
ATOM   9859  O O     . ILE E 2 291 ? 136.895 184.046 169.253 1.00 90.25  ? 273 ILE F O     1 
ATOM   9860  C CB    . ILE E 2 291 ? 135.405 182.279 167.039 1.00 90.25  ? 273 ILE F CB    1 
ATOM   9861  C CG1   . ILE E 2 291 ? 134.647 183.622 167.043 1.00 90.25  ? 273 ILE F CG1   1 
ATOM   9862  C CG2   . ILE E 2 291 ? 134.617 181.328 167.949 1.00 90.25  ? 273 ILE F CG2   1 
ATOM   9863  C CD1   . ILE E 2 291 ? 135.254 184.777 166.256 1.00 90.25  ? 273 ILE F CD1   1 
ATOM   9864  N N     . ASP E 2 292 ? 137.130 181.909 169.902 1.00 96.10  ? 274 ASP F N     1 
ATOM   9865  C CA    . ASP E 2 292 ? 137.400 182.295 171.285 1.00 96.10  ? 274 ASP F CA    1 
ATOM   9866  C C     . ASP E 2 292 ? 138.735 183.019 171.394 1.00 96.10  ? 274 ASP F C     1 
ATOM   9867  O O     . ASP E 2 292 ? 138.839 184.051 172.071 1.00 96.10  ? 274 ASP F O     1 
ATOM   9868  C CB    . ASP E 2 292 ? 137.380 181.064 172.192 1.00 96.10  ? 274 ASP F CB    1 
ATOM   9869  C CG    . ASP E 2 292 ? 137.244 181.418 173.662 1.00 96.10  ? 274 ASP F CG    1 
ATOM   9870  O OD1   . ASP E 2 292 ? 138.122 182.128 174.197 1.00 96.10  ? 274 ASP F OD1   1 
ATOM   9871  O OD2   . ASP E 2 292 ? 136.251 180.986 174.283 1.00 96.10  ? 274 ASP F OD2   1 
ATOM   9872  N N     . THR E 2 293 ? 139.764 182.505 170.713 1.00 96.21  ? 275 THR F N     1 
ATOM   9873  C CA    . THR E 2 293 ? 141.049 183.199 170.691 1.00 96.21  ? 275 THR F CA    1 
ATOM   9874  C C     . THR E 2 293 ? 140.925 184.566 170.027 1.00 96.21  ? 275 THR F C     1 
ATOM   9875  O O     . THR E 2 293 ? 141.533 185.544 170.479 1.00 96.21  ? 275 THR F O     1 
ATOM   9876  C CB    . THR E 2 293 ? 142.095 182.347 169.971 1.00 96.21  ? 275 THR F CB    1 
ATOM   9877  O OG1   . THR E 2 293 ? 141.552 181.855 168.739 1.00 96.21  ? 275 THR F OG1   1 
ATOM   9878  C CG2   . THR E 2 293 ? 142.525 181.175 170.840 1.00 96.21  ? 275 THR F CG2   1 
ATOM   9879  N N     . LYS E 2 294 ? 140.123 184.658 168.965 1.00 95.30  ? 276 LYS F N     1 
ATOM   9880  C CA    . LYS E 2 294 ? 139.994 185.922 168.247 1.00 95.30  ? 276 LYS F CA    1 
ATOM   9881  C C     . LYS E 2 294 ? 139.238 186.964 169.067 1.00 95.30  ? 276 LYS F C     1 
ATOM   9882  O O     . LYS E 2 294 ? 139.639 188.131 169.109 1.00 95.30  ? 276 LYS F O     1 
ATOM   9883  C CB    . LYS E 2 294 ? 139.308 185.693 166.902 1.00 95.30  ? 276 LYS F CB    1 
ATOM   9884  C CG    . LYS E 2 294 ? 140.257 185.177 165.820 1.00 95.30  ? 276 LYS F CG    1 
ATOM   9885  C CD    . LYS E 2 294 ? 139.563 184.329 164.754 1.00 95.30  ? 276 LYS F CD    1 
ATOM   9886  C CE    . LYS E 2 294 ? 138.783 185.184 163.769 1.00 95.30  ? 276 LYS F CE    1 
ATOM   9887  N NZ    . LYS E 2 294 ? 137.805 184.375 162.994 1.00 95.30  ? 276 LYS F NZ    1 
ATOM   9888  N N     . VAL E 2 295 ? 138.138 186.573 169.719 1.00 97.45  ? 277 VAL F N     1 
ATOM   9889  C CA    . VAL E 2 295 ? 137.401 187.537 170.534 1.00 97.45  ? 277 VAL F CA    1 
ATOM   9890  C C     . VAL E 2 295 ? 138.210 187.908 171.770 1.00 97.45  ? 277 VAL F C     1 
ATOM   9891  O O     . VAL E 2 295 ? 138.082 189.024 172.288 1.00 97.45  ? 277 VAL F O     1 
ATOM   9892  C CB    . VAL E 2 295 ? 135.989 187.023 170.907 1.00 97.45  ? 277 VAL F CB    1 
ATOM   9893  C CG1   . VAL E 2 295 ? 135.171 186.675 169.647 1.00 97.45  ? 277 VAL F CG1   1 
ATOM   9894  C CG2   . VAL E 2 295 ? 136.040 185.842 171.880 1.00 97.45  ? 277 VAL F CG2   1 
ATOM   9895  N N     . ALA E 2 296 ? 139.044 186.991 172.275 1.00 97.37  ? 278 ALA F N     1 
ATOM   9896  C CA    . ALA E 2 296 ? 139.974 187.362 173.335 1.00 97.37  ? 278 ALA F CA    1 
ATOM   9897  C C     . ALA E 2 296 ? 140.984 188.391 172.841 1.00 97.37  ? 278 ALA F C     1 
ATOM   9898  O O     . ALA E 2 296 ? 141.315 189.341 173.561 1.00 97.37  ? 278 ALA F O     1 
ATOM   9899  C CB    . ALA E 2 296 ? 140.691 186.121 173.863 1.00 97.37  ? 278 ALA F CB    1 
ATOM   9900  N N     . GLU E 2 297 ? 141.472 188.225 171.609 1.00 99.92  ? 279 GLU F N     1 
ATOM   9901  C CA    . GLU E 2 297 ? 142.501 189.098 171.046 1.00 99.92  ? 279 GLU F CA    1 
ATOM   9902  C C     . GLU E 2 297 ? 141.890 190.262 170.267 1.00 99.92  ? 279 GLU F C     1 
ATOM   9903  O O     . GLU E 2 297 ? 142.067 191.426 170.640 1.00 99.92  ? 279 GLU F O     1 
ATOM   9904  C CB    . GLU E 2 297 ? 143.431 188.284 170.139 1.00 99.92  ? 279 GLU F CB    1 
ATOM   9905  C CG    . GLU E 2 297 ? 144.235 187.201 170.853 1.00 99.92  ? 279 GLU F CG    1 
ATOM   9906  C CD    . GLU E 2 297 ? 144.849 186.205 169.891 1.00 99.92  ? 279 GLU F CD    1 
ATOM   9907  O OE1   . GLU E 2 297 ? 144.087 185.520 169.178 1.00 99.92  ? 279 GLU F OE1   1 
ATOM   9908  O OE2   . GLU E 2 297 ? 146.093 186.105 169.848 1.00 99.92  ? 279 GLU F OE2   1 
ATOM   9909  N N     . TRP E 2 298 ? 141.161 189.958 169.193 1.00 102.67 ? 280 TRP F N     1 
ATOM   9910  C CA    . TRP E 2 298 ? 140.527 190.973 168.349 1.00 102.67 ? 280 TRP F CA    1 
ATOM   9911  C C     . TRP E 2 298 ? 139.147 191.292 168.908 1.00 102.67 ? 280 TRP F C     1 
ATOM   9912  O O     . TRP E 2 298 ? 138.173 190.585 168.635 1.00 102.67 ? 280 TRP F O     1 
ATOM   9913  C CB    . TRP E 2 298 ? 140.425 190.495 166.904 1.00 102.67 ? 280 TRP F CB    1 
ATOM   9914  C CG    . TRP E 2 298 ? 141.735 190.175 166.237 1.00 102.67 ? 280 TRP F CG    1 
ATOM   9915  C CD1   . TRP E 2 298 ? 142.977 190.621 166.592 1.00 102.67 ? 280 TRP F CD1   1 
ATOM   9916  C CD2   . TRP E 2 298 ? 141.923 189.344 165.085 1.00 102.67 ? 280 TRP F CD2   1 
ATOM   9917  N NE1   . TRP E 2 298 ? 143.925 190.114 165.736 1.00 102.67 ? 280 TRP F NE1   1 
ATOM   9918  C CE2   . TRP E 2 298 ? 143.304 189.327 164.802 1.00 102.67 ? 280 TRP F CE2   1 
ATOM   9919  C CE3   . TRP E 2 298 ? 141.058 188.610 164.266 1.00 102.67 ? 280 TRP F CE3   1 
ATOM   9920  C CZ2   . TRP E 2 298 ? 143.838 188.605 163.737 1.00 102.67 ? 280 TRP F CZ2   1 
ATOM   9921  C CZ3   . TRP E 2 298 ? 141.590 187.895 163.211 1.00 102.67 ? 280 TRP F CZ3   1 
ATOM   9922  C CH2   . TRP E 2 298 ? 142.967 187.897 162.955 1.00 102.67 ? 280 TRP F CH2   1 
ATOM   9923  N N     . ARG E 2 299 ? 139.064 192.363 169.693 1.00 105.57 ? 281 ARG F N     1 
ATOM   9924  C CA    . ARG E 2 299 ? 137.786 192.942 170.081 1.00 105.57 ? 281 ARG F CA    1 
ATOM   9925  C C     . ARG E 2 299 ? 137.978 194.440 170.258 1.00 105.57 ? 281 ARG F C     1 
ATOM   9926  O O     . ARG E 2 299 ? 139.089 194.918 170.499 1.00 105.57 ? 281 ARG F O     1 
ATOM   9927  C CB    . ARG E 2 299 ? 137.222 192.308 171.359 1.00 105.57 ? 281 ARG F CB    1 
ATOM   9928  C CG    . ARG E 2 299 ? 135.926 191.534 171.131 1.00 105.57 ? 281 ARG F CG    1 
ATOM   9929  C CD    . ARG E 2 299 ? 135.284 191.086 172.435 1.00 105.57 ? 281 ARG F CD    1 
ATOM   9930  N NE    . ARG E 2 299 ? 133.920 190.608 172.229 1.00 105.57 ? 281 ARG F NE    1 
ATOM   9931  C CZ    . ARG E 2 299 ? 133.129 190.100 173.169 1.00 105.57 ? 281 ARG F CZ    1 
ATOM   9932  N NH1   . ARG E 2 299 ? 133.522 189.978 174.430 1.00 105.57 ? 281 ARG F NH1   1 
ATOM   9933  N NH2   . ARG E 2 299 ? 131.904 189.705 172.835 1.00 105.57 ? 281 ARG F NH2   1 
ATOM   9934  N N     . GLU E 2 300 ? 136.871 195.175 170.120 1.00 115.55 ? 282 GLU F N     1 
ATOM   9935  C CA    . GLU E 2 300 ? 136.877 196.640 170.050 1.00 115.55 ? 282 GLU F CA    1 
ATOM   9936  C C     . GLU E 2 300 ? 137.740 197.145 168.889 1.00 115.55 ? 282 GLU F C     1 
ATOM   9937  O O     . GLU E 2 300 ? 138.360 198.208 168.983 1.00 115.55 ? 282 GLU F O     1 
ATOM   9938  C CB    . GLU E 2 300 ? 137.328 197.273 171.376 1.00 115.55 ? 282 GLU F CB    1 
ATOM   9939  C CG    . GLU E 2 300 ? 136.425 196.974 172.569 1.00 115.55 ? 282 GLU F CG    1 
ATOM   9940  C CD    . GLU E 2 300 ? 135.284 197.963 172.694 1.00 115.55 ? 282 GLU F CD    1 
ATOM   9941  O OE1   . GLU E 2 300 ? 134.304 197.843 171.930 1.00 115.55 ? 282 GLU F OE1   1 
ATOM   9942  O OE2   . GLU E 2 300 ? 135.369 198.863 173.555 1.00 115.55 ? 282 GLU F OE2   1 
ATOM   9943  N N     . GLU E 2 301 ? 137.787 196.372 167.790 1.00 113.89 ? 283 GLU F N     1 
ATOM   9944  C CA    . GLU E 2 301 ? 138.477 196.735 166.556 1.00 113.89 ? 283 GLU F CA    1 
ATOM   9945  C C     . GLU E 2 301 ? 137.593 196.674 165.317 1.00 113.89 ? 283 GLU F C     1 
ATOM   9946  O O     . GLU E 2 301 ? 138.040 197.103 164.248 1.00 113.89 ? 283 GLU F O     1 
ATOM   9947  C CB    . GLU E 2 301 ? 139.691 195.819 166.317 1.00 113.89 ? 283 GLU F CB    1 
ATOM   9948  C CG    . GLU E 2 301 ? 140.554 195.519 167.538 1.00 113.89 ? 283 GLU F CG    1 
ATOM   9949  C CD    . GLU E 2 301 ? 140.967 196.767 168.295 1.00 113.89 ? 283 GLU F CD    1 
ATOM   9950  O OE1   . GLU E 2 301 ? 141.207 197.806 167.646 1.00 113.89 ? 283 GLU F OE1   1 
ATOM   9951  O OE2   . GLU E 2 301 ? 141.057 196.707 169.539 1.00 113.89 ? 283 GLU F OE2   1 
ATOM   9952  N N     . GLY E 2 302 ? 136.368 196.156 165.417 1.00 110.83 ? 284 GLY F N     1 
ATOM   9953  C CA    . GLY E 2 302 ? 135.520 196.008 164.251 1.00 110.83 ? 284 GLY F CA    1 
ATOM   9954  C C     . GLY E 2 302 ? 135.850 194.829 163.366 1.00 110.83 ? 284 GLY F C     1 
ATOM   9955  O O     . GLY E 2 302 ? 135.495 194.848 162.183 1.00 110.83 ? 284 GLY F O     1 
ATOM   9956  N N     . LYS E 2 303 ? 136.517 193.803 163.905 1.00 105.99 ? 285 LYS F N     1 
ATOM   9957  C CA    . LYS E 2 303 ? 136.944 192.618 163.167 1.00 105.99 ? 285 LYS F CA    1 
ATOM   9958  C C     . LYS E 2 303 ? 136.256 191.346 163.639 1.00 105.99 ? 285 LYS F C     1 
ATOM   9959  O O     . LYS E 2 303 ? 135.654 190.640 162.823 1.00 105.99 ? 285 LYS F O     1 
ATOM   9960  C CB    . LYS E 2 303 ? 138.468 192.450 163.286 1.00 105.99 ? 285 LYS F CB    1 
ATOM   9961  C CG    . LYS E 2 303 ? 139.296 193.577 162.669 1.00 105.99 ? 285 LYS F CG    1 
ATOM   9962  C CD    . LYS E 2 303 ? 139.228 193.578 161.143 1.00 105.99 ? 285 LYS F CD    1 
ATOM   9963  C CE    . LYS E 2 303 ? 140.133 194.640 160.538 1.00 105.99 ? 285 LYS F CE    1 
ATOM   9964  N NZ    . LYS E 2 303 ? 139.516 195.993 160.593 1.00 105.99 ? 285 LYS F NZ    1 
ATOM   9965  N N     . ALA E 2 304 ? 136.333 191.037 164.938 1.00 99.54  ? 286 ALA F N     1 
ATOM   9966  C CA    . ALA E 2 304 ? 135.857 189.769 165.495 1.00 99.54  ? 286 ALA F CA    1 
ATOM   9967  C C     . ALA E 2 304 ? 135.108 189.980 166.808 1.00 99.54  ? 286 ALA F C     1 
ATOM   9968  O O     . ALA E 2 304 ? 135.181 189.149 167.718 1.00 99.54  ? 286 ALA F O     1 
ATOM   9969  C CB    . ALA E 2 304 ? 137.017 188.797 165.699 1.00 99.54  ? 286 ALA F CB    1 
ATOM   9970  N N     . GLU E 2 305 ? 134.377 191.087 166.927 1.00 95.61  ? 287 GLU F N     1 
ATOM   9971  C CA    . GLU E 2 305 ? 133.416 191.245 168.014 1.00 95.61  ? 287 GLU F CA    1 
ATOM   9972  C C     . GLU E 2 305 ? 132.194 190.398 167.674 1.00 95.61  ? 287 GLU F C     1 
ATOM   9973  O O     . GLU E 2 305 ? 131.963 190.064 166.511 1.00 95.61  ? 287 GLU F O     1 
ATOM   9974  C CB    . GLU E 2 305 ? 133.087 192.742 168.228 1.00 95.61  ? 287 GLU F CB    1 
ATOM   9975  C CG    . GLU E 2 305 ? 131.674 193.209 168.763 1.00 95.61  ? 287 GLU F CG    1 
ATOM   9976  C CD    . GLU E 2 305 ? 131.615 193.453 170.271 1.00 95.61  ? 287 GLU F CD    1 
ATOM   9977  O OE1   . GLU E 2 305 ? 132.662 193.478 170.952 1.00 95.61  ? 287 GLU F OE1   1 
ATOM   9978  O OE2   . GLU E 2 305 ? 130.490 193.623 170.786 1.00 95.61  ? 287 GLU F OE2   1 
ATOM   9979  N N     . ILE E 2 306 ? 131.424 190.036 168.705 1.00 86.22  ? 288 ILE F N     1 
ATOM   9980  C CA    . ILE E 2 306 ? 130.258 189.164 168.571 1.00 86.22  ? 288 ILE F CA    1 
ATOM   9981  C C     . ILE E 2 306 ? 129.073 189.814 169.270 1.00 86.22  ? 288 ILE F C     1 
ATOM   9982  O O     . ILE E 2 306 ? 129.220 190.394 170.352 1.00 86.22  ? 288 ILE F O     1 
ATOM   9983  C CB    . ILE E 2 306 ? 130.544 187.749 169.134 1.00 86.22  ? 288 ILE F CB    1 
ATOM   9984  C CG1   . ILE E 2 306 ? 131.593 187.078 168.228 1.00 86.22  ? 288 ILE F CG1   1 
ATOM   9985  C CG2   . ILE E 2 306 ? 129.207 186.927 169.293 1.00 86.22  ? 288 ILE F CG2   1 
ATOM   9986  C CD1   . ILE E 2 306 ? 131.975 185.660 168.556 1.00 86.22  ? 288 ILE F CD1   1 
ATOM   9987  N N     . VAL E 2 307 ? 127.907 189.723 168.631 1.00 75.43  ? 289 VAL F N     1 
ATOM   9988  C CA    . VAL E 2 307 ? 126.614 190.117 169.188 1.00 75.43  ? 289 VAL F CA    1 
ATOM   9989  C C     . VAL E 2 307 ? 125.751 188.853 169.171 1.00 75.43  ? 289 VAL F C     1 
ATOM   9990  O O     . VAL E 2 307 ? 125.878 188.062 168.220 1.00 75.43  ? 289 VAL F O     1 
ATOM   9991  C CB    . VAL E 2 307 ? 125.991 191.281 168.387 1.00 75.43  ? 289 VAL F CB    1 
ATOM   9992  C CG1   . VAL E 2 307 ? 125.892 190.973 166.875 1.00 75.43  ? 289 VAL F CG1   1 
ATOM   9993  C CG2   . VAL E 2 307 ? 124.633 191.705 168.954 1.00 75.43  ? 289 VAL F CG2   1 
ATOM   9994  N N     . PRO E 2 308 ? 124.888 188.593 170.167 1.00 64.87  ? 290 PRO F N     1 
ATOM   9995  C CA    . PRO E 2 308 ? 124.012 187.418 170.084 1.00 64.87  ? 290 PRO F CA    1 
ATOM   9996  C C     . PRO E 2 308 ? 122.690 187.748 169.411 1.00 64.87  ? 290 PRO F C     1 
ATOM   9997  O O     . PRO E 2 308 ? 122.059 188.772 169.681 1.00 64.87  ? 290 PRO F O     1 
ATOM   9998  C CB    . PRO E 2 308 ? 123.802 187.048 171.556 1.00 64.87  ? 290 PRO F CB    1 
ATOM   9999  C CG    . PRO E 2 308 ? 123.826 188.342 172.260 1.00 64.87  ? 290 PRO F CG    1 
ATOM   10000 C CD    . PRO E 2 308 ? 124.643 189.312 171.435 1.00 64.87  ? 290 PRO F CD    1 
ATOM   10001 N N     . GLY E 2 309 ? 122.268 186.852 168.520 1.00 57.77  ? 291 GLY F N     1 
ATOM   10002 C CA    . GLY E 2 309 ? 121.044 187.035 167.773 1.00 57.77  ? 291 GLY F CA    1 
ATOM   10003 C C     . GLY E 2 309 ? 119.831 186.513 168.513 1.00 57.77  ? 291 GLY F C     1 
ATOM   10004 O O     . GLY E 2 309 ? 119.923 185.955 169.605 1.00 57.77  ? 291 GLY F O     1 
ATOM   10005 N N     . VAL E 2 310 ? 118.672 186.703 167.879 1.00 50.06  ? 292 VAL F N     1 
ATOM   10006 C CA    . VAL E 2 310 ? 117.385 186.246 168.395 1.00 50.06  ? 292 VAL F CA    1 
ATOM   10007 C C     . VAL E 2 310 ? 116.966 185.031 167.581 1.00 50.06  ? 292 VAL F C     1 
ATOM   10008 O O     . VAL E 2 310 ? 116.369 185.163 166.507 1.00 50.06  ? 292 VAL F O     1 
ATOM   10009 C CB    . VAL E 2 310 ? 116.326 187.367 168.335 1.00 50.06  ? 292 VAL F CB    1 
ATOM   10010 C CG1   . VAL E 2 310 ? 114.909 186.822 168.543 1.00 50.06  ? 292 VAL F CG1   1 
ATOM   10011 C CG2   . VAL E 2 310 ? 116.623 188.439 169.372 1.00 50.06  ? 292 VAL F CG2   1 
ATOM   10012 N N     . LEU E 2 311 ? 117.298 183.842 168.070 1.00 52.25  ? 293 LEU F N     1 
ATOM   10013 C CA    . LEU E 2 311 ? 116.751 182.630 167.485 1.00 52.25  ? 293 LEU F CA    1 
ATOM   10014 C C     . LEU E 2 311 ? 115.248 182.596 167.726 1.00 52.25  ? 293 LEU F C     1 
ATOM   10015 O O     . LEU E 2 311 ? 114.756 183.081 168.749 1.00 52.25  ? 293 LEU F O     1 
ATOM   10016 C CB    . LEU E 2 311 ? 117.421 181.394 168.088 1.00 52.25  ? 293 LEU F CB    1 
ATOM   10017 C CG    . LEU E 2 311 ? 116.950 180.002 167.651 1.00 52.25  ? 293 LEU F CG    1 
ATOM   10018 C CD1   . LEU E 2 311 ? 117.151 179.796 166.162 1.00 52.25  ? 293 LEU F CD1   1 
ATOM   10019 C CD2   . LEU E 2 311 ? 117.693 178.938 168.434 1.00 52.25  ? 293 LEU F CD2   1 
ATOM   10020 N N     . PHE E 2 312 ? 114.521 182.035 166.759 1.00 48.45  ? 294 PHE F N     1 
ATOM   10021 C CA    . PHE E 2 312 ? 113.070 181.888 166.822 1.00 48.45  ? 294 PHE F CA    1 
ATOM   10022 C C     . PHE E 2 312 ? 112.719 180.471 166.403 1.00 48.45  ? 294 PHE F C     1 
ATOM   10023 O O     . PHE E 2 312 ? 113.010 180.069 165.273 1.00 48.45  ? 294 PHE F O     1 
ATOM   10024 C CB    . PHE E 2 312 ? 112.381 182.923 165.919 1.00 48.45  ? 294 PHE F CB    1 
ATOM   10025 C CG    . PHE E 2 312 ? 110.868 182.832 165.886 1.00 48.45  ? 294 PHE F CG    1 
ATOM   10026 C CD1   . PHE E 2 312 ? 110.120 182.610 167.031 1.00 48.45  ? 294 PHE F CD1   1 
ATOM   10027 C CD2   . PHE E 2 312 ? 110.195 183.001 164.690 1.00 48.45  ? 294 PHE F CD2   1 
ATOM   10028 C CE1   . PHE E 2 312 ? 108.744 182.542 166.978 1.00 48.45  ? 294 PHE F CE1   1 
ATOM   10029 C CE2   . PHE E 2 312 ? 108.817 182.936 164.635 1.00 48.45  ? 294 PHE F CE2   1 
ATOM   10030 C CZ    . PHE E 2 312 ? 108.093 182.705 165.780 1.00 48.45  ? 294 PHE F CZ    1 
ATOM   10031 N N     . ILE E 2 313 ? 112.107 179.720 167.318 1.00 50.29  ? 295 ILE F N     1 
ATOM   10032 C CA    . ILE E 2 313 ? 111.740 178.323 167.108 1.00 50.29  ? 295 ILE F CA    1 
ATOM   10033 C C     . ILE E 2 313 ? 110.218 178.302 167.036 1.00 50.29  ? 295 ILE F C     1 
ATOM   10034 O O     . ILE E 2 313 ? 109.539 178.110 168.049 1.00 50.29  ? 295 ILE F O     1 
ATOM   10035 C CB    . ILE E 2 313 ? 112.332 177.449 168.241 1.00 50.29  ? 295 ILE F CB    1 
ATOM   10036 C CG1   . ILE E 2 313 ? 113.868 177.445 168.115 1.00 50.29  ? 295 ILE F CG1   1 
ATOM   10037 C CG2   . ILE E 2 313 ? 111.811 175.968 168.288 1.00 50.29  ? 295 ILE F CG2   1 
ATOM   10038 C CD1   . ILE E 2 313 ? 114.612 176.487 169.038 1.00 50.29  ? 295 ILE F CD1   1 
ATOM   10039 N N     . ASP E 2 314 ? 109.678 178.464 165.833 1.00 53.42  ? 296 ASP F N     1 
ATOM   10040 C CA    . ASP E 2 314 ? 108.238 178.576 165.661 1.00 53.42  ? 296 ASP F CA    1 
ATOM   10041 C C     . ASP E 2 314 ? 107.634 177.182 165.772 1.00 53.42  ? 296 ASP F C     1 
ATOM   10042 O O     . ASP E 2 314 ? 108.189 176.208 165.258 1.00 53.42  ? 296 ASP F O     1 
ATOM   10043 C CB    . ASP E 2 314 ? 107.925 179.213 164.299 1.00 53.42  ? 296 ASP F CB    1 
ATOM   10044 C CG    . ASP E 2 314 ? 106.422 179.247 163.942 1.00 53.42  ? 296 ASP F CG    1 
ATOM   10045 O OD1   . ASP E 2 314 ? 105.532 178.935 164.763 1.00 53.42  ? 296 ASP F OD1   1 
ATOM   10046 O OD2   . ASP E 2 314 ? 106.128 179.608 162.784 1.00 53.42  ? 296 ASP F OD2   1 
ATOM   10047 N N     . GLU E 2 315 ? 106.465 177.110 166.415 1.00 55.51  ? 297 GLU F N     1 
ATOM   10048 C CA    . GLU E 2 315 ? 105.692 175.877 166.595 1.00 55.51  ? 297 GLU F CA    1 
ATOM   10049 C C     . GLU E 2 315 ? 106.558 174.833 167.315 1.00 55.51  ? 297 GLU F C     1 
ATOM   10050 O O     . GLU E 2 315 ? 106.999 173.822 166.770 1.00 55.51  ? 297 GLU F O     1 
ATOM   10051 C CB    . GLU E 2 315 ? 105.122 175.412 165.237 1.00 55.51  ? 297 GLU F CB    1 
ATOM   10052 C CG    . GLU E 2 315 ? 104.541 174.001 165.130 1.00 55.51  ? 297 GLU F CG    1 
ATOM   10053 C CD    . GLU E 2 315 ? 103.707 173.821 163.876 1.00 55.51  ? 297 GLU F CD    1 
ATOM   10054 O OE1   . GLU E 2 315 ? 103.877 174.617 162.928 1.00 55.51  ? 297 GLU F OE1   1 
ATOM   10055 O OE2   . GLU E 2 315 ? 102.881 172.887 163.837 1.00 55.51  ? 297 GLU F OE2   1 
ATOM   10056 N N     . VAL E 2 316 ? 106.864 175.173 168.568 1.00 51.19  ? 298 VAL F N     1 
ATOM   10057 C CA    . VAL E 2 316 ? 107.790 174.370 169.361 1.00 51.19  ? 298 VAL F CA    1 
ATOM   10058 C C     . VAL E 2 316 ? 107.143 173.108 169.925 1.00 51.19  ? 298 VAL F C     1 
ATOM   10059 O O     . VAL E 2 316 ? 107.862 172.198 170.352 1.00 51.19  ? 298 VAL F O     1 
ATOM   10060 C CB    . VAL E 2 316 ? 108.380 175.229 170.494 1.00 51.19  ? 298 VAL F CB    1 
ATOM   10061 C CG1   . VAL E 2 316 ? 107.343 175.504 171.578 1.00 51.19  ? 298 VAL F CG1   1 
ATOM   10062 C CG2   . VAL E 2 316 ? 109.635 174.593 171.085 1.00 51.19  ? 298 VAL F CG2   1 
ATOM   10063 N N     . HIS E 2 317 ? 105.809 173.010 169.931 1.00 53.49  ? 299 HIS F N     1 
ATOM   10064 C CA    . HIS E 2 317 ? 105.167 171.814 170.470 1.00 53.49  ? 299 HIS F CA    1 
ATOM   10065 C C     . HIS E 2 317 ? 105.438 170.568 169.630 1.00 53.49  ? 299 HIS F C     1 
ATOM   10066 O O     . HIS E 2 317 ? 105.284 169.455 170.143 1.00 53.49  ? 299 HIS F O     1 
ATOM   10067 C CB    . HIS E 2 317 ? 103.655 172.027 170.611 1.00 53.49  ? 299 HIS F CB    1 
ATOM   10068 C CG    . HIS E 2 317 ? 102.946 172.296 169.320 1.00 53.49  ? 299 HIS F CG    1 
ATOM   10069 N ND1   . HIS E 2 317 ? 102.502 171.290 168.491 1.00 53.49  ? 299 HIS F ND1   1 
ATOM   10070 C CD2   . HIS E 2 317 ? 102.595 173.459 168.722 1.00 53.49  ? 299 HIS F CD2   1 
ATOM   10071 C CE1   . HIS E 2 317 ? 101.912 171.820 167.435 1.00 53.49  ? 299 HIS F CE1   1 
ATOM   10072 N NE2   . HIS E 2 317 ? 101.955 173.135 167.551 1.00 53.49  ? 299 HIS F NE2   1 
ATOM   10073 N N     . MET E 2 318 ? 105.834 170.722 168.363 1.00 60.92  ? 300 MET F N     1 
ATOM   10074 C CA    . MET E 2 318 ? 106.240 169.577 167.555 1.00 60.92  ? 300 MET F CA    1 
ATOM   10075 C C     . MET E 2 318 ? 107.628 169.055 167.907 1.00 60.92  ? 300 MET F C     1 
ATOM   10076 O O     . MET E 2 318 ? 107.955 167.927 167.524 1.00 60.92  ? 300 MET F O     1 
ATOM   10077 C CB    . MET E 2 318 ? 106.220 169.921 166.060 1.00 60.92  ? 300 MET F CB    1 
ATOM   10078 C CG    . MET E 2 318 ? 104.877 170.374 165.495 1.00 60.92  ? 300 MET F CG    1 
ATOM   10079 S SD    . MET E 2 318 ? 103.957 169.010 164.765 1.00 60.92  ? 300 MET F SD    1 
ATOM   10080 C CE    . MET E 2 318 ? 102.596 169.892 164.010 1.00 60.92  ? 300 MET F CE    1 
ATOM   10081 N N     . LEU E 2 319 ? 108.454 169.837 168.603 1.00 58.06  ? 301 LEU F N     1 
ATOM   10082 C CA    . LEU E 2 319 ? 109.811 169.399 168.900 1.00 58.06  ? 301 LEU F CA    1 
ATOM   10083 C C     . LEU E 2 319 ? 109.807 168.223 169.866 1.00 58.06  ? 301 LEU F C     1 
ATOM   10084 O O     . LEU E 2 319 ? 109.000 168.159 170.797 1.00 58.06  ? 301 LEU F O     1 
ATOM   10085 C CB    . LEU E 2 319 ? 110.635 170.543 169.496 1.00 58.06  ? 301 LEU F CB    1 
ATOM   10086 C CG    . LEU E 2 319 ? 111.187 171.691 168.641 1.00 58.06  ? 301 LEU F CG    1 
ATOM   10087 C CD1   . LEU E 2 319 ? 112.199 172.456 169.471 1.00 58.06  ? 301 LEU F CD1   1 
ATOM   10088 C CD2   . LEU E 2 319 ? 111.830 171.242 167.337 1.00 58.06  ? 301 LEU F CD2   1 
ATOM   10089 N N     . ASP E 2 320 ? 110.730 167.294 169.640 1.00 63.98  ? 302 ASP F N     1 
ATOM   10090 C CA    . ASP E 2 320 ? 110.845 166.095 170.454 1.00 63.98  ? 302 ASP F CA    1 
ATOM   10091 C C     . ASP E 2 320 ? 111.527 166.427 171.779 1.00 63.98  ? 302 ASP F C     1 
ATOM   10092 O O     . ASP E 2 320 ? 112.127 167.491 171.952 1.00 63.98  ? 302 ASP F O     1 
ATOM   10093 C CB    . ASP E 2 320 ? 111.641 165.012 169.712 1.00 63.98  ? 302 ASP F CB    1 
ATOM   10094 C CG    . ASP E 2 320 ? 110.759 164.066 168.906 1.00 63.98  ? 302 ASP F CG    1 
ATOM   10095 O OD1   . ASP E 2 320 ? 109.606 164.423 168.580 1.00 63.98  ? 302 ASP F OD1   1 
ATOM   10096 O OD2   . ASP E 2 320 ? 111.228 162.951 168.595 1.00 63.98  ? 302 ASP F OD2   1 
ATOM   10097 N N     . ILE E 2 321 ? 111.435 165.489 172.726 1.00 58.01  ? 303 ILE F N     1 
ATOM   10098 C CA    . ILE E 2 321 ? 112.173 165.618 173.981 1.00 58.01  ? 303 ILE F CA    1 
ATOM   10099 C C     . ILE E 2 321 ? 113.679 165.604 173.722 1.00 58.01  ? 303 ILE F C     1 
ATOM   10100 O O     . ILE E 2 321 ? 114.451 166.208 174.479 1.00 58.01  ? 303 ILE F O     1 
ATOM   10101 C CB    . ILE E 2 321 ? 111.727 164.510 174.971 1.00 58.01  ? 303 ILE F CB    1 
ATOM   10102 C CG1   . ILE E 2 321 ? 112.263 164.744 176.392 1.00 58.01  ? 303 ILE F CG1   1 
ATOM   10103 C CG2   . ILE E 2 321 ? 112.132 163.111 174.496 1.00 58.01  ? 303 ILE F CG2   1 
ATOM   10104 C CD1   . ILE E 2 321 ? 111.628 165.913 177.111 1.00 58.01  ? 303 ILE F CD1   1 
ATOM   10105 N N     . GLU E 2 322 ? 114.118 164.920 172.658 1.00 61.93  ? 304 GLU F N     1 
ATOM   10106 C CA    . GLU E 2 322 ? 115.511 165.003 172.229 1.00 61.93  ? 304 GLU F CA    1 
ATOM   10107 C C     . GLU E 2 322 ? 115.888 166.438 171.882 1.00 61.93  ? 304 GLU F C     1 
ATOM   10108 O O     . GLU E 2 322 ? 116.959 166.925 172.270 1.00 61.93  ? 304 GLU F O     1 
ATOM   10109 C CB    . GLU E 2 322 ? 115.747 164.096 171.015 1.00 61.93  ? 304 GLU F CB    1 
ATOM   10110 C CG    . GLU E 2 322 ? 115.801 162.581 171.278 1.00 61.93  ? 304 GLU F CG    1 
ATOM   10111 C CD    . GLU E 2 322 ? 114.456 161.961 171.595 1.00 61.93  ? 304 GLU F CD    1 
ATOM   10112 O OE1   . GLU E 2 322 ? 113.457 162.704 171.654 1.00 61.93  ? 304 GLU F OE1   1 
ATOM   10113 O OE2   . GLU E 2 322 ? 114.399 160.730 171.793 1.00 61.93  ? 304 GLU F OE2   1 
ATOM   10114 N N     . CYS E 2 323 ? 115.006 167.136 171.164 1.00 61.69  ? 305 CYS F N     1 
ATOM   10115 C CA    . CYS E 2 323 ? 115.277 168.517 170.783 1.00 61.69  ? 305 CYS F CA    1 
ATOM   10116 C C     . CYS E 2 323 ? 115.303 169.436 171.997 1.00 61.69  ? 305 CYS F C     1 
ATOM   10117 O O     . CYS E 2 323 ? 116.119 170.359 172.062 1.00 61.69  ? 305 CYS F O     1 
ATOM   10118 C CB    . CYS E 2 323 ? 114.232 168.987 169.777 1.00 61.69  ? 305 CYS F CB    1 
ATOM   10119 S SG    . CYS E 2 323 ? 114.168 168.005 168.265 1.00 61.69  ? 305 CYS F SG    1 
ATOM   10120 N N     . PHE E 2 324 ? 114.414 169.209 172.968 1.00 53.17  ? 306 PHE F N     1 
ATOM   10121 C CA    . PHE E 2 324 ? 114.430 170.027 174.178 1.00 53.17  ? 306 PHE F CA    1 
ATOM   10122 C C     . PHE E 2 324 ? 115.692 169.779 174.996 1.00 53.17  ? 306 PHE F C     1 
ATOM   10123 O O     . PHE E 2 324 ? 116.253 170.716 175.578 1.00 53.17  ? 306 PHE F O     1 
ATOM   10124 C CB    . PHE E 2 324 ? 113.186 169.750 175.023 1.00 53.17  ? 306 PHE F CB    1 
ATOM   10125 C CG    . PHE E 2 324 ? 111.910 170.293 174.437 1.00 53.17  ? 306 PHE F CG    1 
ATOM   10126 C CD1   . PHE E 2 324 ? 111.703 171.657 174.317 1.00 53.17  ? 306 PHE F CD1   1 
ATOM   10127 C CD2   . PHE E 2 324 ? 110.911 169.434 174.019 1.00 53.17  ? 306 PHE F CD2   1 
ATOM   10128 C CE1   . PHE E 2 324 ? 110.533 172.150 173.784 1.00 53.17  ? 306 PHE F CE1   1 
ATOM   10129 C CE2   . PHE E 2 324 ? 109.737 169.923 173.486 1.00 53.17  ? 306 PHE F CE2   1 
ATOM   10130 C CZ    . PHE E 2 324 ? 109.548 171.282 173.369 1.00 53.17  ? 306 PHE F CZ    1 
ATOM   10131 N N     . SER E 2 325 ? 116.147 168.524 175.063 1.00 57.89  ? 307 SER F N     1 
ATOM   10132 C CA    . SER E 2 325 ? 117.401 168.233 175.751 1.00 57.89  ? 307 SER F CA    1 
ATOM   10133 C C     . SER E 2 325 ? 118.574 168.915 175.060 1.00 57.89  ? 307 SER F C     1 
ATOM   10134 O O     . SER E 2 325 ? 119.468 169.460 175.723 1.00 57.89  ? 307 SER F O     1 
ATOM   10135 C CB    . SER E 2 325 ? 117.623 166.723 175.818 1.00 57.89  ? 307 SER F CB    1 
ATOM   10136 O OG    . SER E 2 325 ? 116.501 166.067 176.381 1.00 57.89  ? 307 SER F OG    1 
ATOM   10137 N N     . PHE E 2 326 ? 118.582 168.906 173.724 1.00 60.14  ? 308 PHE F N     1 
ATOM   10138 C CA    . PHE E 2 326 ? 119.623 169.620 172.993 1.00 60.14  ? 308 PHE F CA    1 
ATOM   10139 C C     . PHE E 2 326 ? 119.537 171.122 173.236 1.00 60.14  ? 308 PHE F C     1 
ATOM   10140 O O     . PHE E 2 326 ? 120.564 171.803 173.311 1.00 60.14  ? 308 PHE F O     1 
ATOM   10141 C CB    . PHE E 2 326 ? 119.526 169.322 171.499 1.00 60.14  ? 308 PHE F CB    1 
ATOM   10142 C CG    . PHE E 2 326 ? 120.511 170.092 170.674 1.00 60.14  ? 308 PHE F CG    1 
ATOM   10143 C CD1   . PHE E 2 326 ? 121.843 169.723 170.647 1.00 60.14  ? 308 PHE F CD1   1 
ATOM   10144 C CD2   . PHE E 2 326 ? 120.110 171.189 169.933 1.00 60.14  ? 308 PHE F CD2   1 
ATOM   10145 C CE1   . PHE E 2 326 ? 122.755 170.430 169.896 1.00 60.14  ? 308 PHE F CE1   1 
ATOM   10146 C CE2   . PHE E 2 326 ? 121.018 171.900 169.182 1.00 60.14  ? 308 PHE F CE2   1 
ATOM   10147 C CZ    . PHE E 2 326 ? 122.342 171.520 169.165 1.00 60.14  ? 308 PHE F CZ    1 
ATOM   10148 N N     . LEU E 2 327 ? 118.318 171.656 173.341 1.00 56.63  ? 309 LEU F N     1 
ATOM   10149 C CA    . LEU E 2 327 ? 118.147 173.078 173.641 1.00 56.63  ? 309 LEU F CA    1 
ATOM   10150 C C     . LEU E 2 327 ? 118.717 173.421 175.009 1.00 56.63  ? 309 LEU F C     1 
ATOM   10151 O O     . LEU E 2 327 ? 119.369 174.458 175.176 1.00 56.63  ? 309 LEU F O     1 
ATOM   10152 C CB    . LEU E 2 327 ? 116.668 173.477 173.587 1.00 56.63  ? 309 LEU F CB    1 
ATOM   10153 C CG    . LEU E 2 327 ? 116.201 174.357 172.427 1.00 56.63  ? 309 LEU F CG    1 
ATOM   10154 C CD1   . LEU E 2 327 ? 116.518 173.731 171.079 1.00 56.63  ? 309 LEU F CD1   1 
ATOM   10155 C CD2   . LEU E 2 327 ? 114.710 174.616 172.562 1.00 56.63  ? 309 LEU F CD2   1 
ATOM   10156 N N     . ASN E 2 328 ? 118.465 172.568 176.004 1.00 54.33  ? 310 ASN F N     1 
ATOM   10157 C CA    . ASN E 2 328 ? 119.017 172.801 177.335 1.00 54.33  ? 310 ASN F CA    1 
ATOM   10158 C C     . ASN E 2 328 ? 120.537 172.728 177.319 1.00 54.33  ? 310 ASN F C     1 
ATOM   10159 O O     . ASN E 2 328 ? 121.210 173.535 177.971 1.00 54.33  ? 310 ASN F O     1 
ATOM   10160 C CB    . ASN E 2 328 ? 118.451 171.786 178.331 1.00 54.33  ? 310 ASN F CB    1 
ATOM   10161 C CG    . ASN E 2 328 ? 117.055 172.145 178.823 1.00 54.33  ? 310 ASN F CG    1 
ATOM   10162 O OD1   . ASN E 2 328 ? 116.618 173.291 178.736 1.00 54.33  ? 310 ASN F OD1   1 
ATOM   10163 N ND2   . ASN E 2 328 ? 116.351 171.152 179.356 1.00 54.33  ? 310 ASN F ND2   1 
ATOM   10164 N N     . ARG E 2 329 ? 121.100 171.769 176.582 1.00 61.38  ? 311 ARG F N     1 
ATOM   10165 C CA    . ARG E 2 329 ? 122.557 171.673 176.519 1.00 61.38  ? 311 ARG F CA    1 
ATOM   10166 C C     . ARG E 2 329 ? 123.174 172.838 175.751 1.00 61.38  ? 311 ARG F C     1 
ATOM   10167 O O     . ARG E 2 329 ? 124.308 173.233 176.044 1.00 61.38  ? 311 ARG F O     1 
ATOM   10168 C CB    . ARG E 2 329 ? 122.989 170.345 175.891 1.00 61.38  ? 311 ARG F CB    1 
ATOM   10169 C CG    . ARG E 2 329 ? 123.329 169.260 176.908 1.00 61.38  ? 311 ARG F CG    1 
ATOM   10170 C CD    . ARG E 2 329 ? 124.695 169.482 177.555 1.00 61.38  ? 311 ARG F CD    1 
ATOM   10171 N NE    . ARG E 2 329 ? 125.770 168.808 176.832 1.00 61.38  ? 311 ARG F NE    1 
ATOM   10172 C CZ    . ARG E 2 329 ? 126.119 167.532 176.965 1.00 61.38  ? 311 ARG F CZ    1 
ATOM   10173 N NH1   . ARG E 2 329 ? 125.478 166.707 177.783 1.00 61.38  ? 311 ARG F NH1   1 
ATOM   10174 N NH2   . ARG E 2 329 ? 127.139 167.064 176.252 1.00 61.38  ? 311 ARG F NH2   1 
ATOM   10175 N N     . ALA E 2 330 ? 122.457 173.396 174.772 1.00 58.98  ? 312 ALA F N     1 
ATOM   10176 C CA    . ALA E 2 330 ? 122.988 174.471 173.942 1.00 58.98  ? 312 ALA F CA    1 
ATOM   10177 C C     . ALA E 2 330 ? 122.818 175.851 174.560 1.00 58.98  ? 312 ALA F C     1 
ATOM   10178 O O     . ALA E 2 330 ? 123.639 176.737 174.303 1.00 58.98  ? 312 ALA F O     1 
ATOM   10179 C CB    . ALA E 2 330 ? 122.312 174.450 172.570 1.00 58.98  ? 312 ALA F CB    1 
ATOM   10180 N N     . LEU E 2 331 ? 121.768 176.065 175.356 1.00 56.38  ? 313 LEU F N     1 
ATOM   10181 C CA    . LEU E 2 331 ? 121.564 177.377 175.963 1.00 56.38  ? 313 LEU F CA    1 
ATOM   10182 C C     . LEU E 2 331 ? 122.628 177.678 177.010 1.00 56.38  ? 313 LEU F C     1 
ATOM   10183 O O     . LEU E 2 331 ? 123.089 178.819 177.123 1.00 56.38  ? 313 LEU F O     1 
ATOM   10184 C CB    . LEU E 2 331 ? 120.172 177.458 176.586 1.00 56.38  ? 313 LEU F CB    1 
ATOM   10185 C CG    . LEU E 2 331 ? 119.000 177.537 175.610 1.00 56.38  ? 313 LEU F CG    1 
ATOM   10186 C CD1   . LEU E 2 331 ? 117.732 177.014 176.265 1.00 56.38  ? 313 LEU F CD1   1 
ATOM   10187 C CD2   . LEU E 2 331 ? 118.808 178.963 175.130 1.00 56.38  ? 313 LEU F CD2   1 
ATOM   10188 N N     . GLU E 2 332 ? 123.031 176.666 177.785 1.00 64.85  ? 314 GLU F N     1 
ATOM   10189 C CA    . GLU E 2 332 ? 124.020 176.871 178.840 1.00 64.85  ? 314 GLU F CA    1 
ATOM   10190 C C     . GLU E 2 332 ? 125.394 177.257 178.301 1.00 64.85  ? 314 GLU F C     1 
ATOM   10191 O O     . GLU E 2 332 ? 126.206 177.805 179.054 1.00 64.85  ? 314 GLU F O     1 
ATOM   10192 C CB    . GLU E 2 332 ? 124.135 175.614 179.712 1.00 64.85  ? 314 GLU F CB    1 
ATOM   10193 C CG    . GLU E 2 332 ? 124.507 174.322 178.982 1.00 64.85  ? 314 GLU F CG    1 
ATOM   10194 C CD    . GLU E 2 332 ? 124.788 173.183 179.940 1.00 64.85  ? 314 GLU F CD    1 
ATOM   10195 O OE1   . GLU E 2 332 ? 124.310 173.245 181.091 1.00 64.85  ? 314 GLU F OE1   1 
ATOM   10196 O OE2   . GLU E 2 332 ? 125.490 172.230 179.543 1.00 64.85  ? 314 GLU F OE2   1 
ATOM   10197 N N     . ASN E 2 333 ? 125.679 176.969 177.034 1.00 69.48  ? 315 ASN F N     1 
ATOM   10198 C CA    . ASN E 2 333 ? 126.920 177.419 176.422 1.00 69.48  ? 315 ASN F CA    1 
ATOM   10199 C C     . ASN E 2 333 ? 126.958 178.944 176.368 1.00 69.48  ? 315 ASN F C     1 
ATOM   10200 O O     . ASN E 2 333 ? 125.936 179.601 176.152 1.00 69.48  ? 315 ASN F O     1 
ATOM   10201 C CB    . ASN E 2 333 ? 127.047 176.818 175.016 1.00 69.48  ? 315 ASN F CB    1 
ATOM   10202 C CG    . ASN E 2 333 ? 127.996 177.590 174.124 1.00 69.48  ? 315 ASN F CG    1 
ATOM   10203 O OD1   . ASN E 2 333 ? 129.114 177.918 174.524 1.00 69.48  ? 315 ASN F OD1   1 
ATOM   10204 N ND2   . ASN E 2 333 ? 127.545 177.911 172.918 1.00 69.48  ? 315 ASN F ND2   1 
ATOM   10205 N N     . GLU E 2 334 ? 128.149 179.504 176.587 1.00 75.78  ? 316 GLU F N     1 
ATOM   10206 C CA    . GLU E 2 334 ? 128.375 180.938 176.467 1.00 75.78  ? 316 GLU F CA    1 
ATOM   10207 C C     . GLU E 2 334 ? 128.057 181.406 175.045 1.00 75.78  ? 316 GLU F C     1 
ATOM   10208 O O     . GLU E 2 334 ? 127.979 180.606 174.108 1.00 75.78  ? 316 GLU F O     1 
ATOM   10209 C CB    . GLU E 2 334 ? 129.830 181.255 176.844 1.00 75.78  ? 316 GLU F CB    1 
ATOM   10210 C CG    . GLU E 2 334 ? 130.192 182.724 177.122 1.00 75.78  ? 316 GLU F CG    1 
ATOM   10211 C CD    . GLU E 2 334 ? 129.515 183.281 178.357 1.00 75.78  ? 316 GLU F CD    1 
ATOM   10212 O OE1   . GLU E 2 334 ? 128.391 183.810 178.231 1.00 75.78  ? 316 GLU F OE1   1 
ATOM   10213 O OE2   . GLU E 2 334 ? 130.106 183.194 179.454 1.00 75.78  ? 316 GLU F OE2   1 
ATOM   10214 N N     . MET E 2 335 ? 127.873 182.730 174.907 1.00 75.87  ? 317 MET F N     1 
ATOM   10215 C CA    . MET E 2 335 ? 127.556 183.442 173.650 1.00 75.87  ? 317 MET F CA    1 
ATOM   10216 C C     . MET E 2 335 ? 126.438 182.760 172.859 1.00 75.87  ? 317 MET F C     1 
ATOM   10217 O O     . MET E 2 335 ? 126.502 182.630 171.635 1.00 75.87  ? 317 MET F O     1 
ATOM   10218 C CB    . MET E 2 335 ? 128.796 183.671 172.758 1.00 75.87  ? 317 MET F CB    1 
ATOM   10219 C CG    . MET E 2 335 ? 129.614 182.468 172.252 1.00 75.87  ? 317 MET F CG    1 
ATOM   10220 S SD    . MET E 2 335 ? 131.285 182.902 171.756 1.00 75.87  ? 317 MET F SD    1 
ATOM   10221 C CE    . MET E 2 335 ? 131.461 181.796 170.363 1.00 75.87  ? 317 MET F CE    1 
ATOM   10222 N N     . SER E 2 336 ? 125.401 182.327 173.573 1.00 65.49  ? 318 SER F N     1 
ATOM   10223 C CA    . SER E 2 336 ? 124.252 181.670 172.972 1.00 65.49  ? 318 SER F CA    1 
ATOM   10224 C C     . SER E 2 336 ? 123.258 182.711 172.455 1.00 65.49  ? 318 SER F C     1 
ATOM   10225 O O     . SER E 2 336 ? 123.295 183.869 172.878 1.00 65.49  ? 318 SER F O     1 
ATOM   10226 C CB    . SER E 2 336 ? 123.584 180.764 174.002 1.00 65.49  ? 318 SER F CB    1 
ATOM   10227 O OG    . SER E 2 336 ? 123.440 181.430 175.243 1.00 65.49  ? 318 SER F OG    1 
ATOM   10228 N N     . PRO E 2 337 ? 122.358 182.337 171.543 1.00 57.15  ? 319 PRO F N     1 
ATOM   10229 C CA    . PRO E 2 337 ? 121.341 183.291 171.092 1.00 57.15  ? 319 PRO F CA    1 
ATOM   10230 C C     . PRO E 2 337 ? 120.190 183.391 172.080 1.00 57.15  ? 319 PRO F C     1 
ATOM   10231 O O     . PRO E 2 337 ? 119.986 182.529 172.935 1.00 57.15  ? 319 PRO F O     1 
ATOM   10232 C CB    . PRO E 2 337 ? 120.872 182.700 169.762 1.00 57.15  ? 319 PRO F CB    1 
ATOM   10233 C CG    . PRO E 2 337 ? 121.002 181.255 169.952 1.00 57.15  ? 319 PRO F CG    1 
ATOM   10234 C CD    . PRO E 2 337 ? 122.190 181.039 170.857 1.00 57.15  ? 319 PRO F CD    1 
ATOM   10235 N N     . ILE E 2 338 ? 119.429 184.472 171.940 1.00 48.58  ? 320 ILE F N     1 
ATOM   10236 C CA    . ILE E 2 338 ? 118.250 184.698 172.771 1.00 48.58  ? 320 ILE F CA    1 
ATOM   10237 C C     . ILE E 2 338 ? 117.126 183.844 172.199 1.00 48.58  ? 320 ILE F C     1 
ATOM   10238 O O     . ILE E 2 338 ? 116.550 184.173 171.160 1.00 48.58  ? 320 ILE F O     1 
ATOM   10239 C CB    . ILE E 2 338 ? 117.863 186.182 172.812 1.00 48.58  ? 320 ILE F CB    1 
ATOM   10240 C CG1   . ILE E 2 338 ? 118.910 186.992 173.587 1.00 48.58  ? 320 ILE F CG1   1 
ATOM   10241 C CG2   . ILE E 2 338 ? 116.477 186.376 173.435 1.00 48.58  ? 320 ILE F CG2   1 
ATOM   10242 C CD1   . ILE E 2 338 ? 119.103 188.377 173.043 1.00 48.58  ? 320 ILE F CD1   1 
ATOM   10243 N N     . LEU E 2 339 ? 116.809 182.748 172.878 1.00 47.58  ? 321 LEU F N     1 
ATOM   10244 C CA    . LEU E 2 339 ? 115.819 181.814 172.363 1.00 47.58  ? 321 LEU F CA    1 
ATOM   10245 C C     . LEU E 2 339 ? 114.422 182.407 172.475 1.00 47.58  ? 321 LEU F C     1 
ATOM   10246 O O     . LEU E 2 339 ? 114.073 183.014 173.491 1.00 47.58  ? 321 LEU F O     1 
ATOM   10247 C CB    . LEU E 2 339 ? 115.910 180.487 173.120 1.00 47.58  ? 321 LEU F CB    1 
ATOM   10248 C CG    . LEU E 2 339 ? 114.882 179.386 172.843 1.00 47.58  ? 321 LEU F CG    1 
ATOM   10249 C CD1   . LEU E 2 339 ? 114.951 178.920 171.408 1.00 47.58  ? 321 LEU F CD1   1 
ATOM   10250 C CD2   . LEU E 2 339 ? 115.123 178.213 173.769 1.00 47.58  ? 321 LEU F CD2   1 
ATOM   10251 N N     . VAL E 2 340 ? 113.634 182.241 171.416 1.00 44.78  ? 322 VAL F N     1 
ATOM   10252 C CA    . VAL E 2 340 ? 112.217 182.583 171.392 1.00 44.78  ? 322 VAL F CA    1 
ATOM   10253 C C     . VAL E 2 340 ? 111.477 181.403 170.785 1.00 44.78  ? 322 VAL F C     1 
ATOM   10254 O O     . VAL E 2 340 ? 111.947 180.809 169.809 1.00 44.78  ? 322 VAL F O     1 
ATOM   10255 C CB    . VAL E 2 340 ? 111.945 183.876 170.592 1.00 44.78  ? 322 VAL F CB    1 
ATOM   10256 C CG1   . VAL E 2 340 ? 110.443 184.199 170.587 1.00 44.78  ? 322 VAL F CG1   1 
ATOM   10257 C CG2   . VAL E 2 340 ? 112.769 185.034 171.160 1.00 44.78  ? 322 VAL F CG2   1 
ATOM   10258 N N     . VAL E 2 341 ? 110.334 181.049 171.378 1.00 44.98  ? 323 VAL F N     1 
ATOM   10259 C CA    . VAL E 2 341 ? 109.516 179.929 170.930 1.00 44.98  ? 323 VAL F CA    1 
ATOM   10260 C C     . VAL E 2 341 ? 108.067 180.390 170.826 1.00 44.98  ? 323 VAL F C     1 
ATOM   10261 O O     . VAL E 2 341 ? 107.668 181.400 171.410 1.00 44.98  ? 323 VAL F O     1 
ATOM   10262 C CB    . VAL E 2 341 ? 109.649 178.696 171.861 1.00 44.98  ? 323 VAL F CB    1 
ATOM   10263 C CG1   . VAL E 2 341 ? 111.111 178.391 172.136 1.00 44.98  ? 323 VAL F CG1   1 
ATOM   10264 C CG2   . VAL E 2 341 ? 108.938 178.905 173.177 1.00 44.98  ? 323 VAL F CG2   1 
ATOM   10265 N N     . ALA E 2 342 ? 107.286 179.639 170.046 1.00 46.64  ? 324 ALA F N     1 
ATOM   10266 C CA    . ALA E 2 342 ? 105.889 179.943 169.768 1.00 46.64  ? 324 ALA F CA    1 
ATOM   10267 C C     . ALA E 2 342 ? 105.053 178.680 169.905 1.00 46.64  ? 324 ALA F C     1 
ATOM   10268 O O     . ALA E 2 342 ? 105.525 177.573 169.632 1.00 46.64  ? 324 ALA F O     1 
ATOM   10269 C CB    . ALA E 2 342 ? 105.714 180.530 168.366 1.00 46.64  ? 324 ALA F CB    1 
ATOM   10270 N N     . THR E 2 343 ? 103.803 178.857 170.331 1.00 47.97  ? 325 THR F N     1 
ATOM   10271 C CA    . THR E 2 343 ? 102.909 177.739 170.598 1.00 47.97  ? 325 THR F CA    1 
ATOM   10272 C C     . THR E 2 343 ? 101.474 178.219 170.433 1.00 47.97  ? 325 THR F C     1 
ATOM   10273 O O     . THR E 2 343 ? 101.164 179.371 170.744 1.00 47.97  ? 325 THR F O     1 
ATOM   10274 C CB    . THR E 2 343 ? 103.125 177.185 172.015 1.00 47.97  ? 325 THR F CB    1 
ATOM   10275 O OG1   . THR E 2 343 ? 104.479 176.752 172.165 1.00 47.97  ? 325 THR F OG1   1 
ATOM   10276 C CG2   . THR E 2 343 ? 102.213 176.003 172.298 1.00 47.97  ? 325 THR F CG2   1 
ATOM   10277 N N     . ASN E 2 344 ? 100.612 177.334 169.931 1.00 49.20  ? 326 ASN F N     1 
ATOM   10278 C CA    . ASN E 2 344 ? 99.179  177.578 169.792 1.00 49.20  ? 326 ASN F CA    1 
ATOM   10279 C C     . ASN E 2 344 ? 98.382  176.368 170.266 1.00 49.20  ? 326 ASN F C     1 
ATOM   10280 O O     . ASN E 2 344 ? 97.388  175.974 169.651 1.00 49.20  ? 326 ASN F O     1 
ATOM   10281 C CB    . ASN E 2 344 ? 98.830  177.952 168.350 1.00 49.20  ? 326 ASN F CB    1 
ATOM   10282 C CG    . ASN E 2 344 ? 99.309  176.924 167.330 1.00 49.20  ? 326 ASN F CG    1 
ATOM   10283 O OD1   . ASN E 2 344 ? 98.998  175.737 167.423 1.00 49.20  ? 326 ASN F OD1   1 
ATOM   10284 N ND2   . ASN E 2 344 ? 100.073 177.385 166.344 1.00 49.20  ? 326 ASN F ND2   1 
ATOM   10285 N N     . ARG E 2 345 ? 98.817  175.762 171.371 1.00 49.92  ? 327 ARG F N     1 
ATOM   10286 C CA    . ARG E 2 345 ? 98.126  174.644 171.998 1.00 49.92  ? 327 ARG F CA    1 
ATOM   10287 C C     . ARG E 2 345 ? 98.317  174.749 173.503 1.00 49.92  ? 327 ARG F C     1 
ATOM   10288 O O     . ARG E 2 345 ? 99.391  175.133 173.970 1.00 49.92  ? 327 ARG F O     1 
ATOM   10289 C CB    . ARG E 2 345 ? 98.650  173.292 171.491 1.00 49.92  ? 327 ARG F CB    1 
ATOM   10290 C CG    . ARG E 2 345 ? 98.219  172.892 170.067 1.00 49.92  ? 327 ARG F CG    1 
ATOM   10291 C CD    . ARG E 2 345 ? 96.698  172.783 169.864 1.00 49.92  ? 327 ARG F CD    1 
ATOM   10292 N NE    . ARG E 2 345 ? 96.013  172.126 170.975 1.00 49.92  ? 327 ARG F NE    1 
ATOM   10293 C CZ    . ARG E 2 345 ? 94.716  172.217 171.254 1.00 49.92  ? 327 ARG F CZ    1 
ATOM   10294 N NH1   . ARG E 2 345 ? 93.881  172.927 170.507 1.00 49.92  ? 327 ARG F NH1   1 
ATOM   10295 N NH2   . ARG E 2 345 ? 94.238  171.572 172.315 1.00 49.92  ? 327 ARG F NH2   1 
ATOM   10296 N N     . GLY E 2 346 ? 97.274  174.405 174.253 1.00 49.90  ? 328 GLY F N     1 
ATOM   10297 C CA    . GLY E 2 346 ? 97.288  174.600 175.690 1.00 49.90  ? 328 GLY F CA    1 
ATOM   10298 C C     . GLY E 2 346 ? 98.071  173.557 176.459 1.00 49.90  ? 328 GLY F C     1 
ATOM   10299 O O     . GLY E 2 346 ? 99.098  173.877 177.065 1.00 49.90  ? 328 GLY F O     1 
ATOM   10300 N N     . VAL E 2 347 ? 97.596  172.312 176.440 1.00 50.83  ? 329 VAL F N     1 
ATOM   10301 C CA    . VAL E 2 347 ? 98.217  171.191 177.140 1.00 50.83  ? 329 VAL F CA    1 
ATOM   10302 C C     . VAL E 2 347 ? 98.295  170.036 176.155 1.00 50.83  ? 329 VAL F C     1 
ATOM   10303 O O     . VAL E 2 347 ? 97.274  169.650 175.574 1.00 50.83  ? 329 VAL F O     1 
ATOM   10304 C CB    . VAL E 2 347 ? 97.416  170.790 178.397 1.00 50.83  ? 329 VAL F CB    1 
ATOM   10305 C CG1   . VAL E 2 347 ? 98.123  169.666 179.185 1.00 50.83  ? 329 VAL F CG1   1 
ATOM   10306 C CG2   . VAL E 2 347 ? 97.170  172.016 179.271 1.00 50.83  ? 329 VAL F CG2   1 
ATOM   10307 N N     . THR E 2 348 ? 99.502  169.498 175.957 1.00 53.47  ? 330 THR F N     1 
ATOM   10308 C CA    . THR E 2 348 ? 99.723  168.418 174.997 1.00 53.47  ? 330 THR F CA    1 
ATOM   10309 C C     . THR E 2 348 ? 100.696 167.403 175.573 1.00 53.47  ? 330 THR F C     1 
ATOM   10310 O O     . THR E 2 348 ? 101.410 167.666 176.545 1.00 53.47  ? 330 THR F O     1 
ATOM   10311 C CB    . THR E 2 348 ? 100.289 168.903 173.645 1.00 53.47  ? 330 THR F CB    1 
ATOM   10312 O OG1   . THR E 2 348 ? 101.716 168.991 173.726 1.00 53.47  ? 330 THR F OG1   1 
ATOM   10313 C CG2   . THR E 2 348 ? 99.723  170.257 173.225 1.00 53.47  ? 330 THR F CG2   1 
ATOM   10314 N N     . THR E 2 349 ? 100.697 166.223 174.957 1.00 57.18  ? 331 THR F N     1 
ATOM   10315 C CA    . THR E 2 349 ? 101.726 165.233 175.228 1.00 57.18  ? 331 THR F CA    1 
ATOM   10316 C C     . THR E 2 349 ? 103.068 165.721 174.706 1.00 57.18  ? 331 THR F C     1 
ATOM   10317 O O     . THR E 2 349 ? 103.163 166.263 173.601 1.00 57.18  ? 331 THR F O     1 
ATOM   10318 C CB    . THR E 2 349 ? 101.369 163.896 174.579 1.00 57.18  ? 331 THR F CB    1 
ATOM   10319 O OG1   . THR E 2 349 ? 100.935 164.115 173.232 1.00 57.18  ? 331 THR F OG1   1 
ATOM   10320 C CG2   . THR E 2 349 ? 100.270 163.196 175.363 1.00 57.18  ? 331 THR F CG2   1 
ATOM   10321 N N     . ILE E 2 350 ? 104.112 165.534 175.511 1.00 56.74  ? 332 ILE F N     1 
ATOM   10322 C CA    . ILE E 2 350 ? 105.461 165.831 175.052 1.00 56.74  ? 332 ILE F CA    1 
ATOM   10323 C C     . ILE E 2 350 ? 105.815 164.846 173.950 1.00 56.74  ? 332 ILE F C     1 
ATOM   10324 O O     . ILE E 2 350 ? 105.627 163.632 174.099 1.00 56.74  ? 332 ILE F O     1 
ATOM   10325 C CB    . ILE E 2 350 ? 106.472 165.746 176.207 1.00 56.74  ? 332 ILE F CB    1 
ATOM   10326 C CG1   . ILE E 2 350 ? 106.091 166.659 177.388 1.00 56.74  ? 332 ILE F CG1   1 
ATOM   10327 C CG2   . ILE E 2 350 ? 107.890 166.017 175.690 1.00 56.74  ? 332 ILE F CG2   1 
ATOM   10328 C CD1   . ILE E 2 350 ? 105.923 168.124 177.058 1.00 56.74  ? 332 ILE F CD1   1 
ATOM   10329 N N     . ARG E 2 351 ? 106.316 165.362 172.833 1.00 62.43  ? 333 ARG F N     1 
ATOM   10330 C CA    . ARG E 2 351 ? 106.657 164.501 171.710 1.00 62.43  ? 333 ARG F CA    1 
ATOM   10331 C C     . ARG E 2 351 ? 107.857 163.639 172.083 1.00 62.43  ? 333 ARG F C     1 
ATOM   10332 O O     . ARG E 2 351 ? 108.936 164.162 172.380 1.00 62.43  ? 333 ARG F O     1 
ATOM   10333 C CB    . ARG E 2 351 ? 106.953 165.339 170.470 1.00 62.43  ? 333 ARG F CB    1 
ATOM   10334 C CG    . ARG E 2 351 ? 105.699 165.896 169.790 1.00 62.43  ? 333 ARG F CG    1 
ATOM   10335 C CD    . ARG E 2 351 ? 105.411 165.260 168.429 1.00 62.43  ? 333 ARG F CD    1 
ATOM   10336 N NE    . ARG E 2 351 ? 106.483 165.472 167.458 1.00 62.43  ? 333 ARG F NE    1 
ATOM   10337 C CZ    . ARG E 2 351 ? 106.372 165.342 166.139 1.00 62.43  ? 333 ARG F CZ    1 
ATOM   10338 N NH1   . ARG E 2 351 ? 105.235 164.985 165.558 1.00 62.43  ? 333 ARG F NH1   1 
ATOM   10339 N NH2   . ARG E 2 351 ? 107.437 165.574 165.377 1.00 62.43  ? 333 ARG F NH2   1 
ATOM   10340 N N     . GLY E 2 352 ? 107.658 162.319 172.073 1.00 64.66  ? 334 GLY F N     1 
ATOM   10341 C CA    . GLY E 2 352 ? 108.656 161.353 172.483 1.00 64.66  ? 334 GLY F CA    1 
ATOM   10342 C C     . GLY E 2 352 ? 108.442 160.746 173.856 1.00 64.66  ? 334 GLY F C     1 
ATOM   10343 O O     . GLY E 2 352 ? 109.152 159.793 174.200 1.00 64.66  ? 334 GLY F O     1 
ATOM   10344 N N     . THR E 2 353 ? 107.509 161.277 174.654 1.00 62.68  ? 335 THR F N     1 
ATOM   10345 C CA    . THR E 2 353 ? 107.140 160.701 175.943 1.00 62.68  ? 335 THR F CA    1 
ATOM   10346 C C     . THR E 2 353 ? 105.623 160.690 176.059 1.00 62.68  ? 335 THR F C     1 
ATOM   10347 O O     . THR E 2 353 ? 104.909 161.255 175.227 1.00 62.68  ? 335 THR F O     1 
ATOM   10348 C CB    . THR E 2 353 ? 107.731 161.474 177.134 1.00 62.68  ? 335 THR F CB    1 
ATOM   10349 O OG1   . THR E 2 353 ? 106.859 162.551 177.487 1.00 62.68  ? 335 THR F OG1   1 
ATOM   10350 C CG2   . THR E 2 353 ? 109.119 162.026 176.821 1.00 62.68  ? 335 THR F CG2   1 
ATOM   10351 N N     . ASN E 2 354 ? 105.137 160.032 177.113 1.00 65.60  ? 336 ASN F N     1 
ATOM   10352 C CA    . ASN E 2 354 ? 103.707 159.909 177.370 1.00 65.60  ? 336 ASN F CA    1 
ATOM   10353 C C     . ASN E 2 354 ? 103.158 161.042 178.226 1.00 65.60  ? 336 ASN F C     1 
ATOM   10354 O O     . ASN E 2 354 ? 101.995 161.428 178.054 1.00 65.60  ? 336 ASN F O     1 
ATOM   10355 C CB    . ASN E 2 354 ? 103.419 158.569 178.055 1.00 65.60  ? 336 ASN F CB    1 
ATOM   10356 C CG    . ASN E 2 354 ? 101.984 158.449 178.528 1.00 65.60  ? 336 ASN F CG    1 
ATOM   10357 O OD1   . ASN E 2 354 ? 101.652 158.838 179.648 1.00 65.60  ? 336 ASN F OD1   1 
ATOM   10358 N ND2   . ASN E 2 354 ? 101.122 157.914 177.672 1.00 65.60  ? 336 ASN F ND2   1 
ATOM   10359 N N     . GLN E 2 355 ? 103.964 161.586 179.135 1.00 61.44  ? 337 GLN F N     1 
ATOM   10360 C CA    . GLN E 2 355 ? 103.469 162.560 180.098 1.00 61.44  ? 337 GLN F CA    1 
ATOM   10361 C C     . GLN E 2 355 ? 103.097 163.871 179.416 1.00 61.44  ? 337 GLN F C     1 
ATOM   10362 O O     . GLN E 2 355 ? 103.797 164.345 178.518 1.00 61.44  ? 337 GLN F O     1 
ATOM   10363 C CB    . GLN E 2 355 ? 104.524 162.810 181.175 1.00 61.44  ? 337 GLN F CB    1 
ATOM   10364 C CG    . GLN E 2 355 ? 104.602 161.679 182.221 1.00 61.44  ? 337 GLN F CG    1 
ATOM   10365 C CD    . GLN E 2 355 ? 106.014 161.200 182.566 1.00 61.44  ? 337 GLN F CD    1 
ATOM   10366 O OE1   . GLN E 2 355 ? 107.020 161.790 182.170 1.00 61.44  ? 337 GLN F OE1   1 
ATOM   10367 N NE2   . GLN E 2 355 ? 106.081 160.106 183.314 1.00 61.44  ? 337 GLN F NE2   1 
ATOM   10368 N N     . LYS E 2 356 ? 101.984 164.452 179.854 1.00 56.70  ? 338 LYS F N     1 
ATOM   10369 C CA    . LYS E 2 356 ? 101.479 165.704 179.312 1.00 56.70  ? 338 LYS F CA    1 
ATOM   10370 C C     . LYS E 2 356 ? 102.121 166.891 180.016 1.00 56.70  ? 338 LYS F C     1 
ATOM   10371 O O     . LYS E 2 356 ? 102.702 166.764 181.097 1.00 56.70  ? 338 LYS F O     1 
ATOM   10372 C CB    . LYS E 2 356 ? 99.958  165.770 179.448 1.00 56.70  ? 338 LYS F CB    1 
ATOM   10373 C CG    . LYS E 2 356 ? 99.223  164.811 178.527 1.00 56.70  ? 338 LYS F CG    1 
ATOM   10374 C CD    . LYS E 2 356 ? 97.716  164.956 178.647 1.00 56.70  ? 338 LYS F CD    1 
ATOM   10375 C CE    . LYS E 2 356 ? 97.000  164.228 177.523 1.00 56.70  ? 338 LYS F CE    1 
ATOM   10376 N NZ    . LYS E 2 356 ? 95.589  163.908 177.872 1.00 56.70  ? 338 LYS F NZ    1 
ATOM   10377 N N     . SER E 2 357 ? 102.025 168.053 179.375 1.00 51.36  ? 339 SER F N     1 
ATOM   10378 C CA    . SER E 2 357 ? 102.564 169.283 179.936 1.00 51.36  ? 339 SER F CA    1 
ATOM   10379 C C     . SER E 2 357 ? 101.872 170.466 179.264 1.00 51.36  ? 339 SER F C     1 
ATOM   10380 O O     . SER E 2 357 ? 101.323 170.319 178.161 1.00 51.36  ? 339 SER F O     1 
ATOM   10381 C CB    . SER E 2 357 ? 104.084 169.366 179.731 1.00 51.36  ? 339 SER F CB    1 
ATOM   10382 O OG    . SER E 2 357 ? 104.671 170.345 180.566 1.00 51.36  ? 339 SER F OG    1 
ATOM   10383 N N     . PRO E 2 358 ? 101.881 171.650 179.893 1.00 47.22  ? 340 PRO F N     1 
ATOM   10384 C CA    . PRO E 2 358 ? 101.424 172.848 179.178 1.00 47.22  ? 340 PRO F CA    1 
ATOM   10385 C C     . PRO E 2 358 ? 102.321 173.162 177.992 1.00 47.22  ? 340 PRO F C     1 
ATOM   10386 O O     . PRO E 2 358 ? 103.547 173.091 178.082 1.00 47.22  ? 340 PRO F O     1 
ATOM   10387 C CB    . PRO E 2 358 ? 101.501 173.946 180.244 1.00 47.22  ? 340 PRO F CB    1 
ATOM   10388 C CG    . PRO E 2 358 ? 101.403 173.245 181.518 1.00 47.22  ? 340 PRO F CG    1 
ATOM   10389 C CD    . PRO E 2 358 ? 102.129 171.962 181.315 1.00 47.22  ? 340 PRO F CD    1 
ATOM   10390 N N     . HIS E 2 359 ? 101.693 173.488 176.863 1.00 46.50  ? 341 HIS F N     1 
ATOM   10391 C CA    . HIS E 2 359 ? 102.348 173.917 175.628 1.00 46.50  ? 341 HIS F CA    1 
ATOM   10392 C C     . HIS E 2 359 ? 103.232 172.842 174.992 1.00 46.50  ? 341 HIS F C     1 
ATOM   10393 O O     . HIS E 2 359 ? 103.977 173.146 174.053 1.00 46.50  ? 341 HIS F O     1 
ATOM   10394 C CB    . HIS E 2 359 ? 103.178 175.193 175.848 1.00 46.50  ? 341 HIS F CB    1 
ATOM   10395 C CG    . HIS E 2 359 ? 102.379 176.368 176.321 1.00 46.50  ? 341 HIS F CG    1 
ATOM   10396 N ND1   . HIS E 2 359 ? 102.962 177.477 176.895 1.00 46.50  ? 341 HIS F ND1   1 
ATOM   10397 C CD2   . HIS E 2 359 ? 101.048 176.614 176.297 1.00 46.50  ? 341 HIS F CD2   1 
ATOM   10398 C CE1   . HIS E 2 359 ? 102.025 178.352 177.208 1.00 46.50  ? 341 HIS F CE1   1 
ATOM   10399 N NE2   . HIS E 2 359 ? 100.854 177.853 176.856 1.00 46.50  ? 341 HIS F NE2   1 
ATOM   10400 N N     . GLY E 2 360 ? 103.156 171.592 175.443 1.00 49.25  ? 342 GLY F N     1 
ATOM   10401 C CA    . GLY E 2 360 ? 104.010 170.547 174.900 1.00 49.25  ? 342 GLY F CA    1 
ATOM   10402 C C     . GLY E 2 360 ? 105.488 170.790 175.110 1.00 49.25  ? 342 GLY F C     1 
ATOM   10403 O O     . GLY E 2 360 ? 106.295 170.474 174.226 1.00 49.25  ? 342 GLY F O     1 
ATOM   10404 N N     . ILE E 2 361 ? 105.856 171.342 176.265 1.00 47.62  ? 343 ILE F N     1 
ATOM   10405 C CA    . ILE E 2 361 ? 107.226 171.733 176.606 1.00 47.62  ? 343 ILE F CA    1 
ATOM   10406 C C     . ILE E 2 361 ? 107.522 171.104 177.969 1.00 47.62  ? 343 ILE F C     1 
ATOM   10407 O O     . ILE E 2 361 ? 106.597 171.018 178.789 1.00 47.62  ? 343 ILE F O     1 
ATOM   10408 C CB    . ILE E 2 361 ? 107.378 173.266 176.623 1.00 47.62  ? 343 ILE F CB    1 
ATOM   10409 C CG1   . ILE E 2 361 ? 107.181 173.854 175.213 1.00 47.62  ? 343 ILE F CG1   1 
ATOM   10410 C CG2   . ILE E 2 361 ? 108.747 173.675 177.167 1.00 47.62  ? 343 ILE F CG2   1 
ATOM   10411 C CD1   . ILE E 2 361 ? 106.888 175.337 175.181 1.00 47.62  ? 343 ILE F CD1   1 
ATOM   10412 N N     . PRO E 2 362 ? 108.740 170.638 178.276 1.00 50.90  ? 344 PRO F N     1 
ATOM   10413 C CA    . PRO E 2 362 ? 108.985 170.112 179.623 1.00 50.90  ? 344 PRO F CA    1 
ATOM   10414 C C     . PRO E 2 362 ? 108.907 171.193 180.690 1.00 50.90  ? 344 PRO F C     1 
ATOM   10415 O O     . PRO E 2 362 ? 109.076 172.386 180.427 1.00 50.90  ? 344 PRO F O     1 
ATOM   10416 C CB    . PRO E 2 362 ? 110.399 169.531 179.532 1.00 50.90  ? 344 PRO F CB    1 
ATOM   10417 C CG    . PRO E 2 362 ? 110.576 169.214 178.125 1.00 50.90  ? 344 PRO F CG    1 
ATOM   10418 C CD    . PRO E 2 362 ? 109.875 170.304 177.392 1.00 50.90  ? 344 PRO F CD    1 
ATOM   10419 N N     . ILE E 2 363 ? 108.635 170.743 181.918 1.00 44.59  ? 345 ILE F N     1 
ATOM   10420 C CA    . ILE E 2 363 ? 108.482 171.657 183.048 1.00 44.59  ? 345 ILE F CA    1 
ATOM   10421 C C     . ILE E 2 363 ? 109.785 172.387 183.345 1.00 44.59  ? 345 ILE F C     1 
ATOM   10422 O O     . ILE E 2 363 ? 109.769 173.545 183.781 1.00 44.59  ? 345 ILE F O     1 
ATOM   10423 C CB    . ILE E 2 363 ? 107.961 170.900 184.290 1.00 44.59  ? 345 ILE F CB    1 
ATOM   10424 C CG1   . ILE E 2 363 ? 107.607 171.884 185.412 1.00 44.59  ? 345 ILE F CG1   1 
ATOM   10425 C CG2   . ILE E 2 363 ? 108.975 169.855 184.800 1.00 44.59  ? 345 ILE F CG2   1 
ATOM   10426 C CD1   . ILE E 2 363 ? 106.675 171.306 186.454 1.00 44.59  ? 345 ILE F CD1   1 
ATOM   10427 N N     . ASP E 2 364 ? 110.927 171.727 183.133 1.00 47.55  ? 346 ASP F N     1 
ATOM   10428 C CA    . ASP E 2 364 ? 112.210 172.380 183.372 1.00 47.55  ? 346 ASP F CA    1 
ATOM   10429 C C     . ASP E 2 364 ? 112.437 173.537 182.406 1.00 47.55  ? 346 ASP F C     1 
ATOM   10430 O O     . ASP E 2 364 ? 113.126 174.503 182.753 1.00 47.55  ? 346 ASP F O     1 
ATOM   10431 C CB    . ASP E 2 364 ? 113.340 171.342 183.300 1.00 47.55  ? 346 ASP F CB    1 
ATOM   10432 C CG    . ASP E 2 364 ? 113.838 171.081 181.884 1.00 47.55  ? 346 ASP F CG    1 
ATOM   10433 O OD1   . ASP E 2 364 ? 114.658 171.870 181.365 1.00 47.55  ? 346 ASP F OD1   1 
ATOM   10434 O OD2   . ASP E 2 364 ? 113.406 170.073 181.287 1.00 47.55  ? 346 ASP F OD2   1 
ATOM   10435 N N     . LEU E 2 365 ? 111.877 173.458 181.195 1.00 46.42  ? 347 LEU F N     1 
ATOM   10436 C CA    . LEU E 2 365 ? 111.865 174.614 180.303 1.00 46.42  ? 347 LEU F CA    1 
ATOM   10437 C C     . LEU E 2 365 ? 110.841 175.647 180.751 1.00 46.42  ? 347 LEU F C     1 
ATOM   10438 O O     . LEU E 2 365 ? 111.126 176.848 180.752 1.00 46.42  ? 347 LEU F O     1 
ATOM   10439 C CB    . LEU E 2 365 ? 111.561 174.188 178.864 1.00 46.42  ? 347 LEU F CB    1 
ATOM   10440 C CG    . LEU E 2 365 ? 112.726 173.865 177.925 1.00 46.42  ? 347 LEU F CG    1 
ATOM   10441 C CD1   . LEU E 2 365 ? 113.497 175.122 177.535 1.00 46.42  ? 347 LEU F CD1   1 
ATOM   10442 C CD2   . LEU E 2 365 ? 113.641 172.832 178.548 1.00 46.42  ? 347 LEU F CD2   1 
ATOM   10443 N N     . LEU E 2 366 ? 109.648 175.193 181.142 1.00 45.68  ? 348 LEU F N     1 
ATOM   10444 C CA    . LEU E 2 366 ? 108.557 176.106 181.460 1.00 45.68  ? 348 LEU F CA    1 
ATOM   10445 C C     . LEU E 2 366 ? 108.826 176.929 182.712 1.00 45.68  ? 348 LEU F C     1 
ATOM   10446 O O     . LEU E 2 366 ? 108.230 178.000 182.868 1.00 45.68  ? 348 LEU F O     1 
ATOM   10447 C CB    . LEU E 2 366 ? 107.256 175.317 181.635 1.00 45.68  ? 348 LEU F CB    1 
ATOM   10448 C CG    . LEU E 2 366 ? 106.545 174.690 180.426 1.00 45.68  ? 348 LEU F CG    1 
ATOM   10449 C CD1   . LEU E 2 366 ? 105.173 174.220 180.846 1.00 45.68  ? 348 LEU F CD1   1 
ATOM   10450 C CD2   . LEU E 2 366 ? 106.409 175.628 179.234 1.00 45.68  ? 348 LEU F CD2   1 
ATOM   10451 N N     . ASP E 2 367 ? 109.704 176.465 183.599 1.00 43.92  ? 349 ASP F N     1 
ATOM   10452 C CA    . ASP E 2 367 ? 110.100 177.231 184.774 1.00 43.92  ? 349 ASP F CA    1 
ATOM   10453 C C     . ASP E 2 367 ? 111.161 178.297 184.476 1.00 43.92  ? 349 ASP F C     1 
ATOM   10454 O O     . ASP E 2 367 ? 111.685 178.888 185.428 1.00 43.92  ? 349 ASP F O     1 
ATOM   10455 C CB    . ASP E 2 367 ? 110.608 176.274 185.856 1.00 43.92  ? 349 ASP F CB    1 
ATOM   10456 C CG    . ASP E 2 367 ? 109.524 175.341 186.369 1.00 43.92  ? 349 ASP F CG    1 
ATOM   10457 O OD1   . ASP E 2 367 ? 108.334 175.567 186.061 1.00 43.92  ? 349 ASP F OD1   1 
ATOM   10458 O OD2   . ASP E 2 367 ? 109.865 174.377 187.086 1.00 43.92  ? 349 ASP F OD2   1 
ATOM   10459 N N     . ARG E 2 368 ? 111.488 178.550 183.198 1.00 44.91  ? 350 ARG F N     1 
ATOM   10460 C CA    . ARG E 2 368 ? 112.399 179.614 182.789 1.00 44.91  ? 350 ARG F CA    1 
ATOM   10461 C C     . ARG E 2 368 ? 111.846 180.518 181.693 1.00 44.91  ? 350 ARG F C     1 
ATOM   10462 O O     . ARG E 2 368 ? 112.500 181.513 181.364 1.00 44.91  ? 350 ARG F O     1 
ATOM   10463 C CB    . ARG E 2 368 ? 113.727 179.014 182.302 1.00 44.91  ? 350 ARG F CB    1 
ATOM   10464 C CG    . ARG E 2 368 ? 114.586 178.443 183.416 1.00 44.91  ? 350 ARG F CG    1 
ATOM   10465 C CD    . ARG E 2 368 ? 115.851 177.798 182.874 1.00 44.91  ? 350 ARG F CD    1 
ATOM   10466 N NE    . ARG E 2 368 ? 115.586 176.470 182.323 1.00 44.91  ? 350 ARG F NE    1 
ATOM   10467 C CZ    . ARG E 2 368 ? 116.203 175.903 181.289 1.00 44.91  ? 350 ARG F CZ    1 
ATOM   10468 N NH1   . ARG E 2 368 ? 117.209 176.490 180.654 1.00 44.91  ? 350 ARG F NH1   1 
ATOM   10469 N NH2   . ARG E 2 368 ? 115.811 174.698 180.888 1.00 44.91  ? 350 ARG F NH2   1 
ATOM   10470 N N     . LEU E 2 369 ? 110.670 180.225 181.137 1.00 42.60  ? 351 LEU F N     1 
ATOM   10471 C CA    . LEU E 2 369 ? 110.141 180.943 179.985 1.00 42.60  ? 351 LEU F CA    1 
ATOM   10472 C C     . LEU E 2 369 ? 109.291 182.123 180.437 1.00 42.60  ? 351 LEU F C     1 
ATOM   10473 O O     . LEU E 2 369 ? 108.388 181.963 181.262 1.00 42.60  ? 351 LEU F O     1 
ATOM   10474 C CB    . LEU E 2 369 ? 109.300 180.002 179.118 1.00 42.60  ? 351 LEU F CB    1 
ATOM   10475 C CG    . LEU E 2 369 ? 110.006 178.934 178.276 1.00 42.60  ? 351 LEU F CG    1 
ATOM   10476 C CD1   . LEU E 2 369 ? 109.006 177.910 177.793 1.00 42.60  ? 351 LEU F CD1   1 
ATOM   10477 C CD2   . LEU E 2 369 ? 110.701 179.527 177.077 1.00 42.60  ? 351 LEU F CD2   1 
ATOM   10478 N N     . LEU E 2 370 ? 109.585 183.304 179.892 1.00 41.56  ? 352 LEU F N     1 
ATOM   10479 C CA    . LEU E 2 370 ? 108.702 184.461 180.016 1.00 41.56  ? 352 LEU F CA    1 
ATOM   10480 C C     . LEU E 2 370 ? 107.622 184.333 178.951 1.00 41.56  ? 352 LEU F C     1 
ATOM   10481 O O     . LEU E 2 370 ? 107.885 184.553 177.765 1.00 41.56  ? 352 LEU F O     1 
ATOM   10482 C CB    . LEU E 2 370 ? 109.478 185.766 179.841 1.00 41.56  ? 352 LEU F CB    1 
ATOM   10483 C CG    . LEU E 2 370 ? 110.412 186.319 180.929 1.00 41.56  ? 352 LEU F CG    1 
ATOM   10484 C CD1   . LEU E 2 370 ? 109.773 186.324 182.312 1.00 41.56  ? 352 LEU F CD1   1 
ATOM   10485 C CD2   . LEU E 2 370 ? 111.731 185.562 180.956 1.00 41.56  ? 352 LEU F CD2   1 
ATOM   10486 N N     . ILE E 2 371 ? 106.407 183.991 179.368 1.00 42.12  ? 353 ILE F N     1 
ATOM   10487 C CA    . ILE E 2 371 ? 105.340 183.625 178.442 1.00 42.12  ? 353 ILE F CA    1 
ATOM   10488 C C     . ILE E 2 371 ? 104.571 184.890 178.076 1.00 42.12  ? 353 ILE F C     1 
ATOM   10489 O O     . ILE E 2 371 ? 103.813 185.425 178.888 1.00 42.12  ? 353 ILE F O     1 
ATOM   10490 C CB    . ILE E 2 371 ? 104.416 182.558 179.045 1.00 42.12  ? 353 ILE F CB    1 
ATOM   10491 C CG1   . ILE E 2 371 ? 105.151 181.214 179.148 1.00 42.12  ? 353 ILE F CG1   1 
ATOM   10492 C CG2   . ILE E 2 371 ? 103.148 182.382 178.199 1.00 42.12  ? 353 ILE F CG2   1 
ATOM   10493 C CD1   . ILE E 2 371 ? 104.575 180.260 180.165 1.00 42.12  ? 353 ILE F CD1   1 
ATOM   10494 N N     . ILE E 2 372 ? 104.769 185.361 176.848 1.00 42.41  ? 354 ILE F N     1 
ATOM   10495 C CA    . ILE E 2 372 ? 103.935 186.412 176.272 1.00 42.41  ? 354 ILE F CA    1 
ATOM   10496 C C     . ILE E 2 372 ? 102.668 185.766 175.731 1.00 42.41  ? 354 ILE F C     1 
ATOM   10497 O O     . ILE E 2 372 ? 102.730 184.728 175.062 1.00 42.41  ? 354 ILE F O     1 
ATOM   10498 C CB    . ILE E 2 372 ? 104.676 187.168 175.153 1.00 42.41  ? 354 ILE F CB    1 
ATOM   10499 C CG1   . ILE E 2 372 ? 105.988 187.817 175.634 1.00 42.41  ? 354 ILE F CG1   1 
ATOM   10500 C CG2   . ILE E 2 372 ? 103.745 188.221 174.542 1.00 42.41  ? 354 ILE F CG2   1 
ATOM   10501 C CD1   . ILE E 2 372 ? 106.952 188.158 174.501 1.00 42.41  ? 354 ILE F CD1   1 
ATOM   10502 N N     . THR E 2 373 ? 101.520 186.378 176.020 1.00 43.93  ? 355 THR F N     1 
ATOM   10503 C CA    . THR E 2 373 ? 100.215 185.922 175.550 1.00 43.93  ? 355 THR F CA    1 
ATOM   10504 C C     . THR E 2 373 ? 99.637  186.966 174.607 1.00 43.93  ? 355 THR F C     1 
ATOM   10505 O O     . THR E 2 373 ? 99.535  188.143 174.969 1.00 43.93  ? 355 THR F O     1 
ATOM   10506 C CB    . THR E 2 373 ? 99.264  185.680 176.725 1.00 43.93  ? 355 THR F CB    1 
ATOM   10507 O OG1   . THR E 2 373 ? 99.836  184.712 177.612 1.00 43.93  ? 355 THR F OG1   1 
ATOM   10508 C CG2   . THR E 2 373 ? 97.908  185.174 176.239 1.00 43.93  ? 355 THR F CG2   1 
ATOM   10509 N N     . THR E 2 374 ? 99.257  186.529 173.407 1.00 44.79  ? 356 THR F N     1 
ATOM   10510 C CA    . THR E 2 374 ? 98.704  187.397 172.375 1.00 44.79  ? 356 THR F CA    1 
ATOM   10511 C C     . THR E 2 374 ? 97.185  187.278 172.388 1.00 44.79  ? 356 THR F C     1 
ATOM   10512 O O     . THR E 2 374 ? 96.644  186.183 172.208 1.00 44.79  ? 356 THR F O     1 
ATOM   10513 C CB    . THR E 2 374 ? 99.255  187.026 170.999 1.00 44.79  ? 356 THR F CB    1 
ATOM   10514 O OG1   . THR E 2 374 ? 98.884  185.681 170.677 1.00 44.79  ? 356 THR F OG1   1 
ATOM   10515 C CG2   . THR E 2 374 ? 100.769 187.148 170.978 1.00 44.79  ? 356 THR F CG2   1 
ATOM   10516 N N     . GLN E 2 375 ? 96.507  188.400 172.600 1.00 46.90  ? 357 GLN F N     1 
ATOM   10517 C CA    . GLN E 2 375 ? 95.055  188.427 172.607 1.00 46.90  ? 357 GLN F CA    1 
ATOM   10518 C C     . GLN E 2 375 ? 94.523  188.365 171.173 1.00 46.90  ? 357 GLN F C     1 
ATOM   10519 O O     . GLN E 2 375 ? 95.241  188.703 170.230 1.00 46.90  ? 357 GLN F O     1 
ATOM   10520 C CB    . GLN E 2 375 ? 94.558  189.697 173.298 1.00 46.90  ? 357 GLN F CB    1 
ATOM   10521 C CG    . GLN E 2 375 ? 94.958  189.836 174.767 1.00 46.90  ? 357 GLN F CG    1 
ATOM   10522 C CD    . GLN E 2 375 ? 94.278  188.821 175.665 1.00 46.90  ? 357 GLN F CD    1 
ATOM   10523 O OE1   . GLN E 2 375 ? 93.316  188.167 175.267 1.00 46.90  ? 357 GLN F OE1   1 
ATOM   10524 N NE2   . GLN E 2 375 ? 94.780  188.684 176.887 1.00 46.90  ? 357 GLN F NE2   1 
ATOM   10525 N N     . PRO E 2 376 ? 93.275  187.937 170.967 1.00 49.60  ? 358 PRO F N     1 
ATOM   10526 C CA    . PRO E 2 376 ? 92.719  187.979 169.610 1.00 49.60  ? 358 PRO F CA    1 
ATOM   10527 C C     . PRO E 2 376 ? 92.491  189.411 169.151 1.00 49.60  ? 358 PRO F C     1 
ATOM   10528 O O     . PRO E 2 376 ? 92.348  190.337 169.952 1.00 49.60  ? 358 PRO F O     1 
ATOM   10529 C CB    . PRO E 2 376 ? 91.398  187.216 169.737 1.00 49.60  ? 358 PRO F CB    1 
ATOM   10530 C CG    . PRO E 2 376 ? 91.013  187.377 171.145 1.00 49.60  ? 358 PRO F CG    1 
ATOM   10531 C CD    . PRO E 2 376 ? 92.298  187.364 171.915 1.00 49.60  ? 358 PRO F CD    1 
ATOM   10532 N N     . TYR E 2 377 ? 92.468  189.581 167.832 1.00 53.60  ? 359 TYR F N     1 
ATOM   10533 C CA    . TYR E 2 377 ? 92.297  190.904 167.250 1.00 53.60  ? 359 TYR F CA    1 
ATOM   10534 C C     . TYR E 2 377 ? 90.906  191.451 167.546 1.00 53.60  ? 359 TYR F C     1 
ATOM   10535 O O     . TYR E 2 377 ? 89.916  190.714 167.538 1.00 53.60  ? 359 TYR F O     1 
ATOM   10536 C CB    . TYR E 2 377 ? 92.515  190.854 165.736 1.00 53.60  ? 359 TYR F CB    1 
ATOM   10537 C CG    . TYR E 2 377 ? 93.961  190.824 165.283 1.00 53.60  ? 359 TYR F CG    1 
ATOM   10538 C CD1   . TYR E 2 377 ? 94.824  191.879 165.551 1.00 53.60  ? 359 TYR F CD1   1 
ATOM   10539 C CD2   . TYR E 2 377 ? 94.457  189.745 164.568 1.00 53.60  ? 359 TYR F CD2   1 
ATOM   10540 C CE1   . TYR E 2 377 ? 96.136  191.853 165.133 1.00 53.60  ? 359 TYR F CE1   1 
ATOM   10541 C CE2   . TYR E 2 377 ? 95.769  189.711 164.144 1.00 53.60  ? 359 TYR F CE2   1 
ATOM   10542 C CZ    . TYR E 2 377 ? 96.603  190.768 164.429 1.00 53.60  ? 359 TYR F CZ    1 
ATOM   10543 O OH    . TYR E 2 377 ? 97.913  190.740 164.010 1.00 53.60  ? 359 TYR F OH    1 
ATOM   10544 N N     . THR E 2 378 ? 90.842  192.757 167.804 1.00 61.47  ? 360 THR F N     1 
ATOM   10545 C CA    . THR E 2 378 ? 89.594  193.467 168.030 1.00 61.47  ? 360 THR F CA    1 
ATOM   10546 C C     . THR E 2 378 ? 89.081  194.045 166.712 1.00 61.47  ? 360 THR F C     1 
ATOM   10547 O O     . THR E 2 378 ? 89.675  193.859 165.647 1.00 61.47  ? 360 THR F O     1 
ATOM   10548 C CB    . THR E 2 378 ? 89.787  194.567 169.072 1.00 61.47  ? 360 THR F CB    1 
ATOM   10549 O OG1   . THR E 2 378 ? 90.625  195.597 168.532 1.00 61.47  ? 360 THR F OG1   1 
ATOM   10550 C CG2   . THR E 2 378 ? 90.421  194.004 170.336 1.00 61.47  ? 360 THR F CG2   1 
ATOM   10551 N N     . ASP E 2 379 ? 87.955  194.759 166.786 1.00 62.47  ? 361 ASP F N     1 
ATOM   10552 C CA    . ASP E 2 379 ? 87.311  195.265 165.577 1.00 62.47  ? 361 ASP F CA    1 
ATOM   10553 C C     . ASP E 2 379 ? 88.157  196.335 164.900 1.00 62.47  ? 361 ASP F C     1 
ATOM   10554 O O     . ASP E 2 379 ? 88.260  196.362 163.668 1.00 62.47  ? 361 ASP F O     1 
ATOM   10555 C CB    . ASP E 2 379 ? 85.926  195.828 165.911 1.00 62.47  ? 361 ASP F CB    1 
ATOM   10556 C CG    . ASP E 2 379 ? 84.830  194.779 165.855 1.00 62.47  ? 361 ASP F CG    1 
ATOM   10557 O OD1   . ASP E 2 379 ? 85.143  193.570 165.865 1.00 62.47  ? 361 ASP F OD1   1 
ATOM   10558 O OD2   . ASP E 2 379 ? 83.645  195.168 165.801 1.00 62.47  ? 361 ASP F OD2   1 
ATOM   10559 N N     . ASP E 2 380 ? 88.769  197.210 165.708 1.00 65.87  ? 362 ASP F N     1 
ATOM   10560 C CA    . ASP E 2 380 ? 89.594  198.330 165.180 1.00 65.87  ? 362 ASP F CA    1 
ATOM   10561 C C     . ASP E 2 380 ? 90.871  197.765 164.562 1.00 65.87  ? 362 ASP F C     1 
ATOM   10562 O O     . ASP E 2 380 ? 91.396  198.430 163.656 1.00 65.87  ? 362 ASP F O     1 
ATOM   10563 C CB    . ASP E 2 380 ? 89.916  199.337 166.271 1.00 65.87  ? 362 ASP F CB    1 
ATOM   10564 C CG    . ASP E 2 380 ? 88.716  199.972 166.959 1.00 65.87  ? 362 ASP F CG    1 
ATOM   10565 O OD1   . ASP E 2 380 ? 87.587  199.803 166.453 1.00 65.87  ? 362 ASP F OD1   1 
ATOM   10566 O OD2   . ASP E 2 380 ? 88.923  200.631 167.999 1.00 65.87  ? 362 ASP F OD2   1 
ATOM   10567 N N     . ASP E 2 381 ? 91.397  196.649 165.079 1.00 62.62  ? 363 ASP F N     1 
ATOM   10568 C CA    . ASP E 2 381 ? 92.558  195.990 164.488 1.00 62.62  ? 363 ASP F CA    1 
ATOM   10569 C C     . ASP E 2 381 ? 92.194  195.284 163.187 1.00 62.62  ? 363 ASP F C     1 
ATOM   10570 O O     . ASP E 2 381 ? 92.955  195.339 162.215 1.00 62.62  ? 363 ASP F O     1 
ATOM   10571 C CB    . ASP E 2 381 ? 93.165  195.000 165.482 1.00 62.62  ? 363 ASP F CB    1 
ATOM   10572 C CG    . ASP E 2 381 ? 93.555  195.654 166.792 1.00 62.62  ? 363 ASP F CG    1 
ATOM   10573 O OD1   . ASP E 2 381 ? 94.308  196.648 166.759 1.00 62.62  ? 363 ASP F OD1   1 
ATOM   10574 O OD2   . ASP E 2 381 ? 93.109  195.173 167.855 1.00 62.62  ? 363 ASP F OD2   1 
ATOM   10575 N N     . ILE E 2 382 ? 91.035  194.617 163.151 1.00 59.27  ? 364 ILE F N     1 
ATOM   10576 C CA    . ILE E 2 382 ? 90.604  193.932 161.935 1.00 59.27  ? 364 ILE F CA    1 
ATOM   10577 C C     . ILE E 2 382 ? 90.351  194.944 160.824 1.00 59.27  ? 364 ILE F C     1 
ATOM   10578 O O     . ILE E 2 382 ? 90.749  194.732 159.671 1.00 59.27  ? 364 ILE F O     1 
ATOM   10579 C CB    . ILE E 2 382 ? 89.357  193.068 162.218 1.00 59.27  ? 364 ILE F CB    1 
ATOM   10580 C CG1   . ILE E 2 382 ? 89.714  191.872 163.117 1.00 59.27  ? 364 ILE F CG1   1 
ATOM   10581 C CG2   . ILE E 2 382 ? 88.725  192.563 160.902 1.00 59.27  ? 364 ILE F CG2   1 
ATOM   10582 C CD1   . ILE E 2 382 ? 88.523  191.210 163.802 1.00 59.27  ? 364 ILE F CD1   1 
ATOM   10583 N N     . ARG E 2 383 ? 89.691  196.056 161.157 1.00 62.42  ? 365 ARG F N     1 
ATOM   10584 C CA    . ARG E 2 383 ? 89.420  197.099 160.173 1.00 62.42  ? 365 ARG F CA    1 
ATOM   10585 C C     . ARG E 2 383 ? 90.713  197.705 159.642 1.00 62.42  ? 365 ARG F C     1 
ATOM   10586 O O     . ARG E 2 383 ? 90.854  197.924 158.433 1.00 62.42  ? 365 ARG F O     1 
ATOM   10587 C CB    . ARG E 2 383 ? 88.529  198.168 160.809 1.00 62.42  ? 365 ARG F CB    1 
ATOM   10588 C CG    . ARG E 2 383 ? 88.161  199.360 159.925 1.00 62.42  ? 365 ARG F CG    1 
ATOM   10589 C CD    . ARG E 2 383 ? 87.133  200.250 160.625 1.00 62.42  ? 365 ARG F CD    1 
ATOM   10590 N NE    . ARG E 2 383 ? 85.829  200.222 159.965 1.00 62.42  ? 365 ARG F NE    1 
ATOM   10591 C CZ    . ARG E 2 383 ? 85.441  201.003 158.961 1.00 62.42  ? 365 ARG F CZ    1 
ATOM   10592 N NH1   . ARG E 2 383 ? 86.218  201.958 158.466 1.00 62.42  ? 365 ARG F NH1   1 
ATOM   10593 N NH2   . ARG E 2 383 ? 84.229  200.830 158.441 1.00 62.42  ? 365 ARG F NH2   1 
ATOM   10594 N N     . LYS E 2 384 ? 91.680  197.958 160.528 1.00 62.75  ? 366 LYS F N     1 
ATOM   10595 C CA    . LYS E 2 384 ? 92.951  198.527 160.088 1.00 62.75  ? 366 LYS F CA    1 
ATOM   10596 C C     . LYS E 2 384 ? 93.727  197.548 159.217 1.00 62.75  ? 366 LYS F C     1 
ATOM   10597 O O     . LYS E 2 384 ? 94.334  197.950 158.220 1.00 62.75  ? 366 LYS F O     1 
ATOM   10598 C CB    . LYS E 2 384 ? 93.803  198.952 161.290 1.00 62.75  ? 366 LYS F CB    1 
ATOM   10599 C CG    . LYS E 2 384 ? 93.720  200.444 161.668 1.00 62.75  ? 366 LYS F CG    1 
ATOM   10600 C CD    . LYS E 2 384 ? 94.278  201.437 160.621 1.00 62.75  ? 366 LYS F CD    1 
ATOM   10601 C CE    . LYS E 2 384 ? 95.755  201.228 160.288 1.00 62.75  ? 366 LYS F CE    1 
ATOM   10602 N NZ    . LYS E 2 384 ? 96.631  201.351 161.486 1.00 62.75  ? 366 LYS F NZ    1 
ATOM   10603 N N     . ILE E 2 385 ? 93.724  196.261 159.576 1.00 57.80  ? 367 ILE F N     1 
ATOM   10604 C CA    . ILE E 2 385 ? 94.452  195.270 158.787 1.00 57.80  ? 367 ILE F CA    1 
ATOM   10605 C C     . ILE E 2 385 ? 93.821  195.128 157.408 1.00 57.80  ? 367 ILE F C     1 
ATOM   10606 O O     . ILE E 2 385 ? 94.525  195.027 156.395 1.00 57.80  ? 367 ILE F O     1 
ATOM   10607 C CB    . ILE E 2 385 ? 94.508  193.922 159.534 1.00 57.80  ? 367 ILE F CB    1 
ATOM   10608 C CG1   . ILE E 2 385 ? 95.380  194.022 160.793 1.00 57.80  ? 367 ILE F CG1   1 
ATOM   10609 C CG2   . ILE E 2 385 ? 95.060  192.816 158.634 1.00 57.80  ? 367 ILE F CG2   1 
ATOM   10610 C CD1   . ILE E 2 385 ? 95.022  193.022 161.872 1.00 57.80  ? 367 ILE F CD1   1 
ATOM   10611 N N     . LEU E 2 386 ? 92.488  195.129 157.344 1.00 58.05  ? 368 LEU F N     1 
ATOM   10612 C CA    . LEU E 2 386 ? 91.821  195.054 156.050 1.00 58.05  ? 368 LEU F CA    1 
ATOM   10613 C C     . LEU E 2 386 ? 92.080  196.306 155.221 1.00 58.05  ? 368 LEU F C     1 
ATOM   10614 O O     . LEU E 2 386 ? 92.231  196.220 153.999 1.00 58.05  ? 368 LEU F O     1 
ATOM   10615 C CB    . LEU E 2 386 ? 90.323  194.830 156.246 1.00 58.05  ? 368 LEU F CB    1 
ATOM   10616 C CG    . LEU E 2 386 ? 89.930  193.466 156.825 1.00 58.05  ? 368 LEU F CG    1 
ATOM   10617 C CD1   . LEU E 2 386 ? 88.473  193.478 157.270 1.00 58.05  ? 368 LEU F CD1   1 
ATOM   10618 C CD2   . LEU E 2 386 ? 90.187  192.338 155.834 1.00 58.05  ? 368 LEU F CD2   1 
ATOM   10619 N N     . GLU E 2 387 ? 92.151  197.475 155.863 1.00 64.46  ? 369 GLU F N     1 
ATOM   10620 C CA    . GLU E 2 387 ? 92.470  198.696 155.126 1.00 64.46  ? 369 GLU F CA    1 
ATOM   10621 C C     . GLU E 2 387 ? 93.897  198.657 154.584 1.00 64.46  ? 369 GLU F C     1 
ATOM   10622 O O     . GLU E 2 387 ? 94.149  199.100 153.456 1.00 64.46  ? 369 GLU F O     1 
ATOM   10623 C CB    . GLU E 2 387 ? 92.254  199.915 156.030 1.00 64.46  ? 369 GLU F CB    1 
ATOM   10624 C CG    . GLU E 2 387 ? 92.621  201.284 155.432 1.00 64.46  ? 369 GLU F CG    1 
ATOM   10625 C CD    . GLU E 2 387 ? 91.892  201.593 154.136 1.00 64.46  ? 369 GLU F CD    1 
ATOM   10626 O OE1   . GLU E 2 387 ? 90.818  201.003 153.892 1.00 64.46  ? 369 GLU F OE1   1 
ATOM   10627 O OE2   . GLU E 2 387 ? 92.396  202.430 153.358 1.00 64.46  ? 369 GLU F OE2   1 
ATOM   10628 N N     . ILE E 2 388 ? 94.841  198.138 155.374 1.00 62.78  ? 370 ILE F N     1 
ATOM   10629 C CA    . ILE E 2 388 ? 96.224  198.020 154.913 1.00 62.78  ? 370 ILE F CA    1 
ATOM   10630 C C     . ILE E 2 388 ? 96.306  197.056 153.735 1.00 62.78  ? 370 ILE F C     1 
ATOM   10631 O O     . ILE E 2 388 ? 97.022  197.309 152.758 1.00 62.78  ? 370 ILE F O     1 
ATOM   10632 C CB    . ILE E 2 388 ? 97.141  197.601 156.087 1.00 62.78  ? 370 ILE F CB    1 
ATOM   10633 C CG1   . ILE E 2 388 ? 97.300  198.803 157.046 1.00 62.78  ? 370 ILE F CG1   1 
ATOM   10634 C CG2   . ILE E 2 388 ? 98.517  197.024 155.554 1.00 62.78  ? 370 ILE F CG2   1 
ATOM   10635 C CD1   . ILE E 2 388 ? 98.233  198.626 158.250 1.00 62.78  ? 370 ILE F CD1   1 
ATOM   10636 N N     . ARG E 2 389 ? 95.587  195.933 153.808 1.00 62.41  ? 371 ARG F N     1 
ATOM   10637 C CA    . ARG E 2 389 ? 95.605  194.987 152.695 1.00 62.41  ? 371 ARG F CA    1 
ATOM   10638 C C     . ARG E 2 389 ? 94.908  195.553 151.462 1.00 62.41  ? 371 ARG F C     1 
ATOM   10639 O O     . ARG E 2 389 ? 95.301  195.237 150.334 1.00 62.41  ? 371 ARG F O     1 
ATOM   10640 C CB    . ARG E 2 389 ? 94.965  193.663 153.115 1.00 62.41  ? 371 ARG F CB    1 
ATOM   10641 C CG    . ARG E 2 389 ? 95.709  192.917 154.225 1.00 62.41  ? 371 ARG F CG    1 
ATOM   10642 C CD    . ARG E 2 389 ? 96.988  192.256 153.734 1.00 62.41  ? 371 ARG F CD    1 
ATOM   10643 N NE    . ARG E 2 389 ? 98.113  192.527 154.625 1.00 62.41  ? 371 ARG F NE    1 
ATOM   10644 C CZ    . ARG E 2 389 ? 98.365  191.902 155.772 1.00 62.41  ? 371 ARG F CZ    1 
ATOM   10645 N NH1   . ARG E 2 389 ? 97.579  190.941 156.240 1.00 62.41  ? 371 ARG F NH1   1 
ATOM   10646 N NH2   . ARG E 2 389 ? 99.437  192.254 156.477 1.00 62.41  ? 371 ARG F NH2   1 
ATOM   10647 N N     . CYS E 2 390 ? 93.872  196.376 151.651 1.00 65.15  ? 372 CYS F N     1 
ATOM   10648 C CA    . CYS E 2 390 ? 93.256  197.065 150.521 1.00 65.15  ? 372 CYS F CA    1 
ATOM   10649 C C     . CYS E 2 390 ? 94.235  198.027 149.864 1.00 65.15  ? 372 CYS F C     1 
ATOM   10650 O O     . CYS E 2 390 ? 94.319  198.096 148.632 1.00 65.15  ? 372 CYS F O     1 
ATOM   10651 C CB    . CYS E 2 390 ? 92.012  197.824 150.982 1.00 65.15  ? 372 CYS F CB    1 
ATOM   10652 S SG    . CYS E 2 390 ? 90.540  196.812 151.196 1.00 65.15  ? 372 CYS F SG    1 
ATOM   10653 N N     . GLN E 2 391 ? 94.977  198.786 150.672 1.00 68.77  ? 373 GLN F N     1 
ATOM   10654 C CA    . GLN E 2 391 ? 95.945  199.729 150.123 1.00 68.77  ? 373 GLN F CA    1 
ATOM   10655 C C     . GLN E 2 391 ? 97.091  199.003 149.428 1.00 68.77  ? 373 GLN F C     1 
ATOM   10656 O O     . GLN E 2 391 ? 97.616  199.485 148.418 1.00 68.77  ? 373 GLN F O     1 
ATOM   10657 C CB    . GLN E 2 391 ? 96.472  200.636 151.236 1.00 68.77  ? 373 GLN F CB    1 
ATOM   10658 C CG    . GLN E 2 391 ? 97.205  201.900 150.755 1.00 68.77  ? 373 GLN F CG    1 
ATOM   10659 C CD    . GLN E 2 391 ? 98.695  201.701 150.485 1.00 68.77  ? 373 GLN F CD    1 
ATOM   10660 O OE1   . GLN E 2 391 ? 99.274  200.660 150.799 1.00 68.77  ? 373 GLN F OE1   1 
ATOM   10661 N NE2   . GLN E 2 391 ? 99.321  202.715 149.899 1.00 68.77  ? 373 GLN F NE2   1 
ATOM   10662 N N     . GLU E 2 392 ? 97.498  197.846 149.958 1.00 68.43  ? 374 GLU F N     1 
ATOM   10663 C CA    . GLU E 2 392 ? 98.628  197.120 149.387 1.00 68.43  ? 374 GLU F CA    1 
ATOM   10664 C C     . GLU E 2 392 ? 98.287  196.575 148.004 1.00 68.43  ? 374 GLU F C     1 
ATOM   10665 O O     . GLU E 2 392 ? 99.088  196.695 147.070 1.00 68.43  ? 374 GLU F O     1 
ATOM   10666 C CB    . GLU E 2 392 ? 99.044  195.993 150.343 1.00 68.43  ? 374 GLU F CB    1 
ATOM   10667 C CG    . GLU E 2 392 ? 100.263 195.132 149.943 1.00 68.43  ? 374 GLU F CG    1 
ATOM   10668 C CD    . GLU E 2 392 ? 100.215 193.748 150.559 1.00 68.43  ? 374 GLU F CD    1 
ATOM   10669 O OE1   . GLU E 2 392 ? 99.486  192.884 150.027 1.00 68.43  ? 374 GLU F OE1   1 
ATOM   10670 O OE2   . GLU E 2 392 ? 100.908 193.522 151.574 1.00 68.43  ? 374 GLU F OE2   1 
ATOM   10671 N N     . GLU E 2 393 ? 97.104  195.982 147.852 1.00 67.13  ? 375 GLU F N     1 
ATOM   10672 C CA    . GLU E 2 393 ? 96.718  195.287 146.630 1.00 67.13  ? 375 GLU F CA    1 
ATOM   10673 C C     . GLU E 2 393 ? 96.039  196.192 145.599 1.00 67.13  ? 375 GLU F C     1 
ATOM   10674 O O     . GLU E 2 393 ? 95.587  195.688 144.565 1.00 67.13  ? 375 GLU F O     1 
ATOM   10675 C CB    . GLU E 2 393 ? 95.803  194.109 146.980 1.00 67.13  ? 375 GLU F CB    1 
ATOM   10676 C CG    . GLU E 2 393 ? 96.534  192.969 147.679 1.00 67.13  ? 375 GLU F CG    1 
ATOM   10677 C CD    . GLU E 2 393 ? 95.641  191.778 147.967 1.00 67.13  ? 375 GLU F CD    1 
ATOM   10678 O OE1   . GLU E 2 393 ? 94.705  191.525 147.181 1.00 67.13  ? 375 GLU F OE1   1 
ATOM   10679 O OE2   . GLU E 2 393 ? 95.877  191.095 148.985 1.00 67.13  ? 375 GLU F OE2   1 
ATOM   10680 N N     . ASP E 2 394 ? 95.985  197.511 145.836 1.00 72.45  ? 376 ASP F N     1 
ATOM   10681 C CA    . ASP E 2 394 ? 95.362  198.464 144.912 1.00 72.45  ? 376 ASP F CA    1 
ATOM   10682 C C     . ASP E 2 394 ? 93.886  198.135 144.686 1.00 72.45  ? 376 ASP F C     1 
ATOM   10683 O O     . ASP E 2 394 ? 93.422  198.006 143.551 1.00 72.45  ? 376 ASP F O     1 
ATOM   10684 C CB    . ASP E 2 394 ? 96.119  198.524 143.581 1.00 72.45  ? 376 ASP F CB    1 
ATOM   10685 C CG    . ASP E 2 394 ? 97.621  198.679 143.761 1.00 72.45  ? 376 ASP F CG    1 
ATOM   10686 O OD1   . ASP E 2 394 ? 98.197  198.042 144.666 1.00 72.45  ? 376 ASP F OD1   1 
ATOM   10687 O OD2   . ASP E 2 394 ? 98.231  199.445 142.986 1.00 72.45  ? 376 ASP F OD2   1 
ATOM   10688 N N     . VAL E 2 395 ? 93.153  197.999 145.792 1.00 67.54  ? 377 VAL F N     1 
ATOM   10689 C CA    . VAL E 2 395 ? 91.728  197.680 145.800 1.00 67.54  ? 377 VAL F CA    1 
ATOM   10690 C C     . VAL E 2 395 ? 91.004  198.784 146.554 1.00 67.54  ? 377 VAL F C     1 
ATOM   10691 O O     . VAL E 2 395 ? 91.375  199.110 147.688 1.00 67.54  ? 377 VAL F O     1 
ATOM   10692 C CB    . VAL E 2 395 ? 91.461  196.306 146.445 1.00 67.54  ? 377 VAL F CB    1 
ATOM   10693 C CG1   . VAL E 2 395 ? 89.956  195.977 146.424 1.00 67.54  ? 377 VAL F CG1   1 
ATOM   10694 C CG2   . VAL E 2 395 ? 92.293  195.226 145.741 1.00 67.54  ? 377 VAL F CG2   1 
ATOM   10695 N N     . GLU E 2 396 ? 89.975  199.351 145.923 1.00 69.15  ? 378 GLU F N     1 
ATOM   10696 C CA    . GLU E 2 396 ? 89.139  200.398 146.500 1.00 69.15  ? 378 GLU F CA    1 
ATOM   10697 C C     . GLU E 2 396 ? 87.742  199.844 146.736 1.00 69.15  ? 378 GLU F C     1 
ATOM   10698 O O     . GLU E 2 396 ? 87.191  199.153 145.872 1.00 69.15  ? 378 GLU F O     1 
ATOM   10699 C CB    . GLU E 2 396 ? 89.079  201.616 145.576 1.00 69.15  ? 378 GLU F CB    1 
ATOM   10700 C CG    . GLU E 2 396 ? 90.455  202.146 145.170 1.00 69.15  ? 378 GLU F CG    1 
ATOM   10701 C CD    . GLU E 2 396 ? 90.462  203.632 144.834 1.00 69.15  ? 378 GLU F CD    1 
ATOM   10702 O OE1   . GLU E 2 396 ? 89.383  204.210 144.587 1.00 69.15  ? 378 GLU F OE1   1 
ATOM   10703 O OE2   . GLU E 2 396 ? 91.562  204.224 144.816 1.00 69.15  ? 378 GLU F OE2   1 
ATOM   10704 N N     . MET E 2 397 ? 87.175  200.143 147.904 1.00 67.76  ? 379 MET F N     1 
ATOM   10705 C CA    . MET E 2 397 ? 85.855  199.651 148.273 1.00 67.76  ? 379 MET F CA    1 
ATOM   10706 C C     . MET E 2 397 ? 85.214  200.585 149.287 1.00 67.76  ? 379 MET F C     1 
ATOM   10707 O O     . MET E 2 397 ? 85.892  201.174 150.133 1.00 67.76  ? 379 MET F O     1 
ATOM   10708 C CB    . MET E 2 397 ? 85.930  198.213 148.805 1.00 67.76  ? 379 MET F CB    1 
ATOM   10709 C CG    . MET E 2 397 ? 87.260  197.812 149.417 1.00 67.76  ? 379 MET F CG    1 
ATOM   10710 S SD    . MET E 2 397 ? 87.130  196.279 150.352 1.00 67.76  ? 379 MET F SD    1 
ATOM   10711 C CE    . MET E 2 397 ? 86.653  196.909 151.944 1.00 67.76  ? 379 MET F CE    1 
ATOM   10712 N N     . ASN E 2 398 ? 83.892  200.708 149.185 1.00 69.09  ? 380 ASN F N     1 
ATOM   10713 C CA    . ASN E 2 398 ? 83.150  201.701 149.951 1.00 69.09  ? 380 ASN F CA    1 
ATOM   10714 C C     . ASN E 2 398 ? 83.048  201.279 151.418 1.00 69.09  ? 380 ASN F C     1 
ATOM   10715 O O     . ASN E 2 398 ? 83.496  200.202 151.823 1.00 69.09  ? 380 ASN F O     1 
ATOM   10716 C CB    . ASN E 2 398 ? 81.773  201.945 149.319 1.00 69.09  ? 380 ASN F CB    1 
ATOM   10717 C CG    . ASN E 2 398 ? 80.894  200.688 149.253 1.00 69.09  ? 380 ASN F CG    1 
ATOM   10718 O OD1   . ASN E 2 398 ? 80.620  200.038 150.263 1.00 69.09  ? 380 ASN F OD1   1 
ATOM   10719 N ND2   . ASN E 2 398 ? 80.450  200.348 148.047 1.00 69.09  ? 380 ASN F ND2   1 
ATOM   10720 N N     . GLU E 2 399 ? 82.434  202.150 152.222 1.00 70.60  ? 381 GLU F N     1 
ATOM   10721 C CA    . GLU E 2 399 ? 82.419  201.962 153.668 1.00 70.60  ? 381 GLU F CA    1 
ATOM   10722 C C     . GLU E 2 399 ? 81.440  200.877 154.098 1.00 70.60  ? 381 GLU F C     1 
ATOM   10723 O O     . GLU E 2 399 ? 81.674  200.215 155.115 1.00 70.60  ? 381 GLU F O     1 
ATOM   10724 C CB    . GLU E 2 399 ? 82.076  203.277 154.384 1.00 70.60  ? 381 GLU F CB    1 
ATOM   10725 C CG    . GLU E 2 399 ? 82.793  204.552 153.887 1.00 70.60  ? 381 GLU F CG    1 
ATOM   10726 C CD    . GLU E 2 399 ? 84.282  204.574 154.190 1.00 70.60  ? 381 GLU F CD    1 
ATOM   10727 O OE1   . GLU E 2 399 ? 84.829  203.550 154.645 1.00 70.60  ? 381 GLU F OE1   1 
ATOM   10728 O OE2   . GLU E 2 399 ? 84.913  205.628 153.964 1.00 70.60  ? 381 GLU F OE2   1 
ATOM   10729 N N     . GLU E 2 400 ? 80.342  200.690 153.361 1.00 68.15  ? 382 GLU F N     1 
ATOM   10730 C CA    . GLU E 2 400 ? 79.427  199.592 153.660 1.00 68.15  ? 382 GLU F CA    1 
ATOM   10731 C C     . GLU E 2 400 ? 80.124  198.251 153.468 1.00 68.15  ? 382 GLU F C     1 
ATOM   10732 O O     . GLU E 2 400 ? 80.017  197.349 154.312 1.00 68.15  ? 382 GLU F O     1 
ATOM   10733 C CB    . GLU E 2 400 ? 78.185  199.702 152.767 1.00 68.15  ? 382 GLU F CB    1 
ATOM   10734 C CG    . GLU E 2 400 ? 77.087  198.643 152.976 1.00 68.15  ? 382 GLU F CG    1 
ATOM   10735 C CD    . GLU E 2 400 ? 76.390  198.758 154.319 1.00 68.15  ? 382 GLU F CD    1 
ATOM   10736 O OE1   . GLU E 2 400 ? 76.668  199.721 155.063 1.00 68.15  ? 382 GLU F OE1   1 
ATOM   10737 O OE2   . GLU E 2 400 ? 75.558  197.880 154.630 1.00 68.15  ? 382 GLU F OE2   1 
ATOM   10738 N N     . ALA E 2 401 ? 80.856  198.111 152.359 1.00 67.05  ? 383 ALA F N     1 
ATOM   10739 C CA    . ALA E 2 401 ? 81.613  196.891 152.108 1.00 67.05  ? 383 ALA F CA    1 
ATOM   10740 C C     . ALA E 2 401 ? 82.689  196.688 153.164 1.00 67.05  ? 383 ALA F C     1 
ATOM   10741 O O     . ALA E 2 401 ? 82.897  195.566 153.635 1.00 67.05  ? 383 ALA F O     1 
ATOM   10742 C CB    . ALA E 2 401 ? 82.234  196.937 150.713 1.00 67.05  ? 383 ALA F CB    1 
ATOM   10743 N N     . LYS E 2 402 ? 83.368  197.770 153.560 1.00 65.71  ? 384 LYS F N     1 
ATOM   10744 C CA    . LYS E 2 402 ? 84.405  197.670 154.586 1.00 65.71  ? 384 LYS F CA    1 
ATOM   10745 C C     . LYS E 2 402 ? 83.825  197.221 155.921 1.00 65.71  ? 384 LYS F C     1 
ATOM   10746 O O     . LYS E 2 402 ? 84.400  196.358 156.594 1.00 65.71  ? 384 LYS F O     1 
ATOM   10747 C CB    . LYS E 2 402 ? 85.128  199.010 154.746 1.00 65.71  ? 384 LYS F CB    1 
ATOM   10748 C CG    . LYS E 2 402 ? 86.620  198.884 155.037 1.00 65.71  ? 384 LYS F CG    1 
ATOM   10749 C CD    . LYS E 2 402 ? 87.245  200.186 155.535 1.00 65.71  ? 384 LYS F CD    1 
ATOM   10750 C CE    . LYS E 2 402 ? 87.229  201.311 154.496 1.00 65.71  ? 384 LYS F CE    1 
ATOM   10751 N NZ    . LYS E 2 402 ? 88.044  200.986 153.293 1.00 65.71  ? 384 LYS F NZ    1 
ATOM   10752 N N     . GLN E 2 403 ? 82.675  197.775 156.310 1.00 63.87  ? 385 GLN F N     1 
ATOM   10753 C CA    . GLN E 2 403 ? 82.092  197.413 157.599 1.00 63.87  ? 385 GLN F CA    1 
ATOM   10754 C C     . GLN E 2 403 ? 81.586  195.973 157.573 1.00 63.87  ? 385 GLN F C     1 
ATOM   10755 O O     . GLN E 2 403 ? 81.769  195.230 158.548 1.00 63.87  ? 385 GLN F O     1 
ATOM   10756 C CB    . GLN E 2 403 ? 81.012  198.459 157.981 1.00 63.87  ? 385 GLN F CB    1 
ATOM   10757 C CG    . GLN E 2 403 ? 79.846  198.166 159.004 1.00 63.87  ? 385 GLN F CG    1 
ATOM   10758 C CD    . GLN E 2 403 ? 78.794  197.128 158.596 1.00 63.87  ? 385 GLN F CD    1 
ATOM   10759 O OE1   . GLN E 2 403 ? 78.208  197.214 157.517 1.00 63.87  ? 385 GLN F OE1   1 
ATOM   10760 N NE2   . GLN E 2 403 ? 78.565  196.143 159.459 1.00 63.87  ? 385 GLN F NE2   1 
ATOM   10761 N N     . LEU E 2 404 ? 80.953  195.555 156.471 1.00 60.55  ? 386 LEU F N     1 
ATOM   10762 C CA    . LEU E 2 404 ? 80.459  194.183 156.404 1.00 60.55  ? 386 LEU F CA    1 
ATOM   10763 C C     . LEU E 2 404 ? 81.615  193.192 156.360 1.00 60.55  ? 386 LEU F C     1 
ATOM   10764 O O     . LEU E 2 404 ? 81.527  192.103 156.940 1.00 60.55  ? 386 LEU F O     1 
ATOM   10765 C CB    . LEU E 2 404 ? 79.517  194.018 155.204 1.00 60.55  ? 386 LEU F CB    1 
ATOM   10766 C CG    . LEU E 2 404 ? 79.005  192.621 154.786 1.00 60.55  ? 386 LEU F CG    1 
ATOM   10767 C CD1   . LEU E 2 404 ? 77.646  192.761 154.090 1.00 60.55  ? 386 LEU F CD1   1 
ATOM   10768 C CD2   . LEU E 2 404 ? 79.963  191.848 153.853 1.00 60.55  ? 386 LEU F CD2   1 
ATOM   10769 N N     . LEU E 2 405 ? 82.714  193.551 155.695 1.00 57.50  ? 387 LEU F N     1 
ATOM   10770 C CA    . LEU E 2 405 ? 83.880  192.677 155.698 1.00 57.50  ? 387 LEU F CA    1 
ATOM   10771 C C     . LEU E 2 405 ? 84.536  192.623 157.069 1.00 57.50  ? 387 LEU F C     1 
ATOM   10772 O O     . LEU E 2 405 ? 85.063  191.577 157.455 1.00 57.50  ? 387 LEU F O     1 
ATOM   10773 C CB    . LEU E 2 405 ? 84.887  193.133 154.648 1.00 57.50  ? 387 LEU F CB    1 
ATOM   10774 C CG    . LEU E 2 405 ? 85.705  191.994 154.051 1.00 57.50  ? 387 LEU F CG    1 
ATOM   10775 C CD1   . LEU E 2 405 ? 84.958  191.319 152.915 1.00 57.50  ? 387 LEU F CD1   1 
ATOM   10776 C CD2   . LEU E 2 405 ? 87.024  192.527 153.578 1.00 57.50  ? 387 LEU F CD2   1 
ATOM   10777 N N     . THR E 2 406 ? 84.525  193.733 157.812 1.00 60.06  ? 388 THR F N     1 
ATOM   10778 C CA    . THR E 2 406 ? 85.015  193.703 159.187 1.00 60.06  ? 388 THR F CA    1 
ATOM   10779 C C     . THR E 2 406 ? 84.162  192.779 160.046 1.00 60.06  ? 388 THR F C     1 
ATOM   10780 O O     . THR E 2 406 ? 84.688  192.026 160.874 1.00 60.06  ? 388 THR F O     1 
ATOM   10781 C CB    . THR E 2 406 ? 85.029  195.116 159.773 1.00 60.06  ? 388 THR F CB    1 
ATOM   10782 O OG1   . THR E 2 406 ? 85.921  195.944 159.017 1.00 60.06  ? 388 THR F OG1   1 
ATOM   10783 C CG2   . THR E 2 406 ? 85.476  195.095 161.230 1.00 60.06  ? 388 THR F CG2   1 
ATOM   10784 N N     . LEU E 2 407 ? 82.840  192.822 159.854 1.00 59.29  ? 389 LEU F N     1 
ATOM   10785 C CA    . LEU E 2 407 ? 81.950  191.907 160.565 1.00 59.29  ? 389 LEU F CA    1 
ATOM   10786 C C     . LEU E 2 407 ? 82.242  190.457 160.195 1.00 59.29  ? 389 LEU F C     1 
ATOM   10787 O O     . LEU E 2 407 ? 82.255  189.574 161.064 1.00 59.29  ? 389 LEU F O     1 
ATOM   10788 C CB    . LEU E 2 407 ? 80.494  192.264 160.254 1.00 59.29  ? 389 LEU F CB    1 
ATOM   10789 C CG    . LEU E 2 407 ? 79.369  191.311 160.678 1.00 59.29  ? 389 LEU F CG    1 
ATOM   10790 C CD1   . LEU E 2 407 ? 79.442  191.002 162.164 1.00 59.29  ? 389 LEU F CD1   1 
ATOM   10791 C CD2   . LEU E 2 407 ? 78.021  191.915 160.323 1.00 59.29  ? 389 LEU F CD2   1 
ATOM   10792 N N     . ILE E 2 408 ? 82.474  190.198 158.906 1.00 55.19  ? 390 ILE F N     1 
ATOM   10793 C CA    . ILE E 2 408 ? 82.759  188.839 158.442 1.00 55.19  ? 390 ILE F CA    1 
ATOM   10794 C C     . ILE E 2 408 ? 84.074  188.352 159.040 1.00 55.19  ? 390 ILE F C     1 
ATOM   10795 O O     . ILE E 2 408 ? 84.190  187.200 159.474 1.00 55.19  ? 390 ILE F O     1 
ATOM   10796 C CB    . ILE E 2 408 ? 82.743  188.801 156.891 1.00 55.19  ? 390 ILE F CB    1 
ATOM   10797 C CG1   . ILE E 2 408 ? 81.297  188.515 156.426 1.00 55.19  ? 390 ILE F CG1   1 
ATOM   10798 C CG2   . ILE E 2 408 ? 83.794  187.769 156.286 1.00 55.19  ? 390 ILE F CG2   1 
ATOM   10799 C CD1   . ILE E 2 408 ? 81.047  188.446 154.920 1.00 55.19  ? 390 ILE F CD1   1 
ATOM   10800 N N     . GLY E 2 409 ? 85.086  189.220 159.062 1.00 54.81  ? 391 GLY F N     1 
ATOM   10801 C CA    . GLY E 2 409 ? 86.367  188.839 159.628 1.00 54.81  ? 391 GLY F CA    1 
ATOM   10802 C C     . GLY E 2 409 ? 86.300  188.607 161.124 1.00 54.81  ? 391 GLY F C     1 
ATOM   10803 O O     . GLY E 2 409 ? 86.986  187.729 161.654 1.00 54.81  ? 391 GLY F O     1 
ATOM   10804 N N     . ARG E 2 410 ? 85.492  189.404 161.828 1.00 58.53  ? 392 ARG F N     1 
ATOM   10805 C CA    . ARG E 2 410 ? 85.275  189.169 163.251 1.00 58.53  ? 392 ARG F CA    1 
ATOM   10806 C C     . ARG E 2 410 ? 84.615  187.816 163.471 1.00 58.53  ? 392 ARG F C     1 
ATOM   10807 O O     . ARG E 2 410 ? 85.054  187.024 164.312 1.00 58.53  ? 392 ARG F O     1 
ATOM   10808 C CB    . ARG E 2 410 ? 84.415  190.296 163.838 1.00 58.53  ? 392 ARG F CB    1 
ATOM   10809 C CG    . ARG E 2 410 ? 84.016  190.149 165.325 1.00 58.53  ? 392 ARG F CG    1 
ATOM   10810 C CD    . ARG E 2 410 ? 83.152  191.313 165.794 1.00 58.53  ? 392 ARG F CD    1 
ATOM   10811 N NE    . ARG E 2 410 ? 81.736  190.956 165.856 1.00 58.53  ? 392 ARG F NE    1 
ATOM   10812 C CZ    . ARG E 2 410 ? 80.711  191.793 165.730 1.00 58.53  ? 392 ARG F CZ    1 
ATOM   10813 N NH1   . ARG E 2 410 ? 80.878  193.102 165.586 1.00 58.53  ? 392 ARG F NH1   1 
ATOM   10814 N NH2   . ARG E 2 410 ? 79.474  191.306 165.765 1.00 58.53  ? 392 ARG F NH2   1 
ATOM   10815 N N     . ASP E 2 411 ? 83.552  187.535 162.719 1.00 56.79  ? 393 ASP F N     1 
ATOM   10816 C CA    . ASP E 2 411 ? 82.804  186.306 162.948 1.00 56.79  ? 393 ASP F CA    1 
ATOM   10817 C C     . ASP E 2 411 ? 83.578  185.086 162.466 1.00 56.79  ? 393 ASP F C     1 
ATOM   10818 O O     . ASP E 2 411 ? 83.649  184.076 163.177 1.00 56.79  ? 393 ASP F O     1 
ATOM   10819 C CB    . ASP E 2 411 ? 81.443  186.386 162.259 1.00 56.79  ? 393 ASP F CB    1 
ATOM   10820 C CG    . ASP E 2 411 ? 80.422  185.452 162.876 1.00 56.79  ? 393 ASP F CG    1 
ATOM   10821 O OD1   . ASP E 2 411 ? 80.719  184.247 163.015 1.00 56.79  ? 393 ASP F OD1   1 
ATOM   10822 O OD2   . ASP E 2 411 ? 79.320  185.924 163.225 1.00 56.79  ? 393 ASP F OD2   1 
ATOM   10823 N N     . THR E 2 412 ? 84.181  185.165 161.276 1.00 49.90  ? 394 THR F N     1 
ATOM   10824 C CA    . THR E 2 412 ? 84.704  183.987 160.588 1.00 49.90  ? 394 THR F CA    1 
ATOM   10825 C C     . THR E 2 412 ? 86.212  183.810 160.762 1.00 49.90  ? 394 THR F C     1 
ATOM   10826 O O     . THR E 2 412 ? 86.643  182.853 161.410 1.00 49.90  ? 394 THR F O     1 
ATOM   10827 C CB    . THR E 2 412 ? 84.331  184.088 159.099 1.00 49.90  ? 394 THR F CB    1 
ATOM   10828 O OG1   . THR E 2 412 ? 82.982  184.554 158.976 1.00 49.90  ? 394 THR F OG1   1 
ATOM   10829 C CG2   . THR E 2 412 ? 84.457  182.750 158.417 1.00 49.90  ? 394 THR F CG2   1 
ATOM   10830 N N     . SER E 2 413 ? 87.016  184.736 160.230 1.00 50.99  ? 395 SER F N     1 
ATOM   10831 C CA    . SER E 2 413 ? 88.474  184.695 160.334 1.00 50.99  ? 395 SER F CA    1 
ATOM   10832 C C     . SER E 2 413 ? 89.079  185.899 159.626 1.00 50.99  ? 395 SER F C     1 
ATOM   10833 O O     . SER E 2 413 ? 88.498  186.407 158.664 1.00 50.99  ? 395 SER F O     1 
ATOM   10834 C CB    . SER E 2 413 ? 89.049  183.411 159.728 1.00 50.99  ? 395 SER F CB    1 
ATOM   10835 O OG    . SER E 2 413 ? 90.443  183.540 159.512 1.00 50.99  ? 395 SER F OG    1 
ATOM   10836 N N     . LEU E 2 414 ? 90.264  186.334 160.053 1.00 53.65  ? 396 LEU F N     1 
ATOM   10837 C CA    . LEU E 2 414 ? 90.911  187.456 159.382 1.00 53.65  ? 396 LEU F CA    1 
ATOM   10838 C C     . LEU E 2 414 ? 91.452  187.045 158.016 1.00 53.65  ? 396 LEU F C     1 
ATOM   10839 O O     . LEU E 2 414 ? 91.304  187.784 157.034 1.00 53.65  ? 396 LEU F O     1 
ATOM   10840 C CB    . LEU E 2 414 ? 92.030  188.015 160.262 1.00 53.65  ? 396 LEU F CB    1 
ATOM   10841 C CG    . LEU E 2 414 ? 92.848  189.204 159.743 1.00 53.65  ? 396 LEU F CG    1 
ATOM   10842 C CD1   . LEU E 2 414 ? 91.967  190.380 159.346 1.00 53.65  ? 396 LEU F CD1   1 
ATOM   10843 C CD2   . LEU E 2 414 ? 93.853  189.634 160.793 1.00 53.65  ? 396 LEU F CD2   1 
ATOM   10844 N N     . ARG E 2 415 ? 92.083  185.871 157.934 1.00 49.55  ? 397 ARG F N     1 
ATOM   10845 C CA    . ARG E 2 415 ? 92.644  185.417 156.666 1.00 49.55  ? 397 ARG F CA    1 
ATOM   10846 C C     . ARG E 2 415 ? 91.556  185.121 155.644 1.00 49.55  ? 397 ARG F C     1 
ATOM   10847 O O     . ARG E 2 415 ? 91.767  185.311 154.440 1.00 49.55  ? 397 ARG F O     1 
ATOM   10848 C CB    . ARG E 2 415 ? 93.507  184.182 156.895 1.00 49.55  ? 397 ARG F CB    1 
ATOM   10849 C CG    . ARG E 2 415 ? 94.867  184.495 157.482 1.00 49.55  ? 397 ARG F CG    1 
ATOM   10850 C CD    . ARG E 2 415 ? 95.560  183.232 157.934 1.00 49.55  ? 397 ARG F CD    1 
ATOM   10851 N NE    . ARG E 2 415 ? 96.974  183.448 158.222 1.00 49.55  ? 397 ARG F NE    1 
ATOM   10852 C CZ    . ARG E 2 415 ? 97.457  184.092 159.279 1.00 49.55  ? 397 ARG F CZ    1 
ATOM   10853 N NH1   . ARG E 2 415 ? 96.667  184.622 160.203 1.00 49.55  ? 397 ARG F NH1   1 
ATOM   10854 N NH2   . ARG E 2 415 ? 98.775  184.208 159.417 1.00 49.55  ? 397 ARG F NH2   1 
ATOM   10855 N N     . TYR E 2 416 ? 90.392  184.657 156.102 1.00 46.62  ? 398 TYR F N     1 
ATOM   10856 C CA    . TYR E 2 416 ? 89.264  184.463 155.198 1.00 46.62  ? 398 TYR F CA    1 
ATOM   10857 C C     . TYR E 2 416 ? 88.820  185.789 154.593 1.00 46.62  ? 398 TYR F C     1 
ATOM   10858 O O     . TYR E 2 416 ? 88.558  185.876 153.387 1.00 46.62  ? 398 TYR F O     1 
ATOM   10859 C CB    . TYR E 2 416 ? 88.119  183.792 155.953 1.00 46.62  ? 398 TYR F CB    1 
ATOM   10860 C CG    . TYR E 2 416 ? 86.857  183.602 155.149 1.00 46.62  ? 398 TYR F CG    1 
ATOM   10861 C CD1   . TYR E 2 416 ? 86.816  182.711 154.091 1.00 46.62  ? 398 TYR F CD1   1 
ATOM   10862 C CD2   . TYR E 2 416 ? 85.700  184.295 155.466 1.00 46.62  ? 398 TYR F CD2   1 
ATOM   10863 C CE1   . TYR E 2 416 ? 85.665  182.527 153.360 1.00 46.62  ? 398 TYR F CE1   1 
ATOM   10864 C CE2   . TYR E 2 416 ? 84.542  184.116 154.742 1.00 46.62  ? 398 TYR F CE2   1 
ATOM   10865 C CZ    . TYR E 2 416 ? 84.530  183.229 153.691 1.00 46.62  ? 398 TYR F CZ    1 
ATOM   10866 O OH    . TYR E 2 416 ? 83.380  183.046 152.960 1.00 46.62  ? 398 TYR F OH    1 
ATOM   10867 N N     . ALA E 2 417 ? 88.766  186.844 155.410 1.00 50.59  ? 399 ALA F N     1 
ATOM   10868 C CA    . ALA E 2 417 ? 88.432  188.167 154.894 1.00 50.59  ? 399 ALA F CA    1 
ATOM   10869 C C     . ALA E 2 417 ? 89.506  188.675 153.935 1.00 50.59  ? 399 ALA F C     1 
ATOM   10870 O O     . ALA E 2 417 ? 89.203  189.353 152.943 1.00 50.59  ? 399 ALA F O     1 
ATOM   10871 C CB    . ALA E 2 417 ? 88.239  189.141 156.052 1.00 50.59  ? 399 ALA F CB    1 
ATOM   10872 N N     . ILE E 2 418 ? 90.771  188.356 154.214 1.00 51.60  ? 400 ILE F N     1 
ATOM   10873 C CA    . ILE E 2 418 ? 91.853  188.802 153.341 1.00 51.60  ? 400 ILE F CA    1 
ATOM   10874 C C     . ILE E 2 418 ? 91.764  188.103 151.986 1.00 51.60  ? 400 ILE F C     1 
ATOM   10875 O O     . ILE E 2 418 ? 92.067  188.699 150.947 1.00 51.60  ? 400 ILE F O     1 
ATOM   10876 C CB    . ILE E 2 418 ? 93.218  188.582 154.024 1.00 51.60  ? 400 ILE F CB    1 
ATOM   10877 C CG1   . ILE E 2 418 ? 93.389  189.554 155.203 1.00 51.60  ? 400 ILE F CG1   1 
ATOM   10878 C CG2   . ILE E 2 418 ? 94.372  188.776 153.027 1.00 51.60  ? 400 ILE F CG2   1 
ATOM   10879 C CD1   . ILE E 2 418 ? 94.403  189.120 156.253 1.00 51.60  ? 400 ILE F CD1   1 
ATOM   10880 N N     . HIS E 2 419 ? 91.371  186.828 151.975 1.00 47.02  ? 401 HIS F N     1 
ATOM   10881 C CA    . HIS E 2 419 ? 91.102  186.152 150.706 1.00 47.02  ? 401 HIS F CA    1 
ATOM   10882 C C     . HIS E 2 419 ? 89.910  186.784 149.995 1.00 47.02  ? 401 HIS F C     1 
ATOM   10883 O O     . HIS E 2 419 ? 89.908  186.934 148.761 1.00 47.02  ? 401 HIS F O     1 
ATOM   10884 C CB    . HIS E 2 419 ? 90.842  184.664 150.946 1.00 47.02  ? 401 HIS F CB    1 
ATOM   10885 C CG    . HIS E 2 419 ? 92.006  183.926 151.529 1.00 47.02  ? 401 HIS F CG    1 
ATOM   10886 N ND1   . HIS E 2 419 ? 91.884  182.669 152.082 1.00 47.02  ? 401 HIS F ND1   1 
ATOM   10887 C CD2   . HIS E 2 419 ? 93.313  184.261 151.646 1.00 47.02  ? 401 HIS F CD2   1 
ATOM   10888 C CE1   . HIS E 2 419 ? 93.064  182.263 152.514 1.00 47.02  ? 401 HIS F CE1   1 
ATOM   10889 N NE2   . HIS E 2 419 ? 93.948  183.211 152.262 1.00 47.02  ? 401 HIS F NE2   1 
ATOM   10890 N N     . LEU E 2 420 ? 88.880  187.145 150.768 1.00 48.46  ? 402 LEU F N     1 
ATOM   10891 C CA    . LEU E 2 420 ? 87.696  187.794 150.211 1.00 48.46  ? 402 LEU F CA    1 
ATOM   10892 C C     . LEU E 2 420 ? 88.029  189.114 149.537 1.00 48.46  ? 402 LEU F C     1 
ATOM   10893 O O     . LEU E 2 420 ? 87.345  189.497 148.586 1.00 48.46  ? 402 LEU F O     1 
ATOM   10894 C CB    . LEU E 2 420 ? 86.655  188.040 151.304 1.00 48.46  ? 402 LEU F CB    1 
ATOM   10895 C CG    . LEU E 2 420 ? 85.498  187.056 151.472 1.00 48.46  ? 402 LEU F CG    1 
ATOM   10896 C CD1   . LEU E 2 420 ? 85.946  185.642 151.821 1.00 48.46  ? 402 LEU F CD1   1 
ATOM   10897 C CD2   . LEU E 2 420 ? 84.549  187.577 152.539 1.00 48.46  ? 402 LEU F CD2   1 
ATOM   10898 N N     . ILE E 2 421 ? 89.055  189.823 150.021 1.00 55.02  ? 403 ILE F N     1 
ATOM   10899 C CA    . ILE E 2 421 ? 89.458  191.087 149.395 1.00 55.02  ? 403 ILE F CA    1 
ATOM   10900 C C     . ILE E 2 421 ? 89.866  190.855 147.943 1.00 55.02  ? 403 ILE F C     1 
ATOM   10901 O O     . ILE E 2 421 ? 89.343  191.499 147.025 1.00 55.02  ? 403 ILE F O     1 
ATOM   10902 C CB    . ILE E 2 421 ? 90.598  191.747 150.207 1.00 55.02  ? 403 ILE F CB    1 
ATOM   10903 C CG1   . ILE E 2 421 ? 90.064  192.426 151.483 1.00 55.02  ? 403 ILE F CG1   1 
ATOM   10904 C CG2   . ILE E 2 421 ? 91.457  192.739 149.366 1.00 55.02  ? 403 ILE F CG2   1 
ATOM   10905 C CD1   . ILE E 2 421 ? 89.117  193.630 151.287 1.00 55.02  ? 403 ILE F CD1   1 
ATOM   10906 N N     . THR E 2 422 ? 90.778  189.909 147.714 1.00 49.07  ? 404 THR F N     1 
ATOM   10907 C CA    . THR E 2 422 ? 91.247  189.629 146.359 1.00 49.07  ? 404 THR F CA    1 
ATOM   10908 C C     . THR E 2 422 ? 90.129  189.068 145.490 1.00 49.07  ? 404 THR F C     1 
ATOM   10909 O O     . THR E 2 422 ? 89.970  189.469 144.323 1.00 49.07  ? 404 THR F O     1 
ATOM   10910 C CB    . THR E 2 422 ? 92.411  188.644 146.416 1.00 49.07  ? 404 THR F CB    1 
ATOM   10911 O OG1   . THR E 2 422 ? 93.232  188.936 147.553 1.00 49.07  ? 404 THR F OG1   1 
ATOM   10912 C CG2   . THR E 2 422 ? 93.250  188.727 145.163 1.00 49.07  ? 404 THR F CG2   1 
ATOM   10913 N N     . ALA E 2 423 ? 89.347  188.138 146.046 1.00 47.17  ? 405 ALA F N     1 
ATOM   10914 C CA    . ALA E 2 423 ? 88.290  187.505 145.266 1.00 47.17  ? 405 ALA F CA    1 
ATOM   10915 C C     . ALA E 2 423 ? 87.209  188.507 144.874 1.00 47.17  ? 405 ALA F C     1 
ATOM   10916 O O     . ALA E 2 423 ? 86.751  188.513 143.726 1.00 47.17  ? 405 ALA F O     1 
ATOM   10917 C CB    . ALA E 2 423 ? 87.706  186.341 146.056 1.00 47.17  ? 405 ALA F CB    1 
ATOM   10918 N N     . ALA E 2 424 ? 86.818  189.390 145.795 1.00 51.47  ? 406 ALA F N     1 
ATOM   10919 C CA    . ALA E 2 424 ? 85.843  190.419 145.467 1.00 51.47  ? 406 ALA F CA    1 
ATOM   10920 C C     . ALA E 2 424 ? 86.419  191.462 144.523 1.00 51.47  ? 406 ALA F C     1 
ATOM   10921 O O     . ALA E 2 424 ? 85.674  192.031 143.717 1.00 51.47  ? 406 ALA F O     1 
ATOM   10922 C CB    . ALA E 2 424 ? 85.343  191.092 146.741 1.00 51.47  ? 406 ALA F CB    1 
ATOM   10923 N N     . ALA E 2 425 ? 87.726  191.733 144.609 1.00 54.24  ? 407 ALA F N     1 
ATOM   10924 C CA    . ALA E 2 425 ? 88.353  192.655 143.668 1.00 54.24  ? 407 ALA F CA    1 
ATOM   10925 C C     . ALA E 2 425 ? 88.232  192.140 142.243 1.00 54.24  ? 407 ALA F C     1 
ATOM   10926 O O     . ALA E 2 425 ? 87.801  192.870 141.341 1.00 54.24  ? 407 ALA F O     1 
ATOM   10927 C CB    . ALA E 2 425 ? 89.820  192.868 144.038 1.00 54.24  ? 407 ALA F CB    1 
ATOM   10928 N N     . LEU E 2 426 ? 88.554  190.860 142.030 1.00 49.49  ? 408 LEU F N     1 
ATOM   10929 C CA    . LEU E 2 426 ? 88.401  190.316 140.680 1.00 49.49  ? 408 LEU F CA    1 
ATOM   10930 C C     . LEU E 2 426 ? 86.937  190.124 140.293 1.00 49.49  ? 408 LEU F C     1 
ATOM   10931 O O     . LEU E 2 426 ? 86.604  190.207 139.104 1.00 49.49  ? 408 LEU F O     1 
ATOM   10932 C CB    . LEU E 2 426 ? 89.189  189.014 140.507 1.00 49.49  ? 408 LEU F CB    1 
ATOM   10933 C CG    . LEU E 2 426 ? 90.507  189.204 139.734 1.00 49.49  ? 408 LEU F CG    1 
ATOM   10934 C CD1   . LEU E 2 426 ? 91.372  187.979 139.828 1.00 49.49  ? 408 LEU F CD1   1 
ATOM   10935 C CD2   . LEU E 2 426 ? 90.280  189.522 138.231 1.00 49.49  ? 408 LEU F CD2   1 
ATOM   10936 N N     . SER E 2 427 ? 86.049  189.886 141.263 1.00 50.76  ? 409 SER F N     1 
ATOM   10937 C CA    . SER E 2 427 ? 84.625  189.816 140.946 1.00 50.76  ? 409 SER F CA    1 
ATOM   10938 C C     . SER E 2 427 ? 84.112  191.156 140.436 1.00 50.76  ? 409 SER F C     1 
ATOM   10939 O O     . SER E 2 427 ? 83.332  191.208 139.479 1.00 50.76  ? 409 SER F O     1 
ATOM   10940 C CB    . SER E 2 427 ? 83.832  189.374 142.175 1.00 50.76  ? 409 SER F CB    1 
ATOM   10941 O OG    . SER E 2 427 ? 82.446  189.295 141.885 1.00 50.76  ? 409 SER F OG    1 
ATOM   10942 N N     . CYS E 2 428 ? 84.544  192.252 141.061 1.00 59.25  ? 410 CYS F N     1 
ATOM   10943 C CA    . CYS E 2 428 ? 84.173  193.575 140.571 1.00 59.25  ? 410 CYS F CA    1 
ATOM   10944 C C     . CYS E 2 428 ? 84.849  193.888 139.244 1.00 59.25  ? 410 CYS F C     1 
ATOM   10945 O O     . CYS E 2 428 ? 84.268  194.588 138.407 1.00 59.25  ? 410 CYS F O     1 
ATOM   10946 C CB    . CYS E 2 428 ? 84.529  194.637 141.609 1.00 59.25  ? 410 CYS F CB    1 
ATOM   10947 S SG    . CYS E 2 428 ? 84.298  196.340 141.052 1.00 59.25  ? 410 CYS F SG    1 
ATOM   10948 N N     . GLN E 2 429 ? 86.074  193.394 139.037 1.00 55.16  ? 411 GLN F N     1 
ATOM   10949 C CA    . GLN E 2 429 ? 86.745  193.604 137.758 1.00 55.16  ? 411 GLN F CA    1 
ATOM   10950 C C     . GLN E 2 429 ? 86.006  192.903 136.626 1.00 55.16  ? 411 GLN F C     1 
ATOM   10951 O O     . GLN E 2 429 ? 85.998  193.396 135.493 1.00 55.16  ? 411 GLN F O     1 
ATOM   10952 C CB    . GLN E 2 429 ? 88.193  193.115 137.843 1.00 55.16  ? 411 GLN F CB    1 
ATOM   10953 C CG    . GLN E 2 429 ? 88.936  192.962 136.495 1.00 55.16  ? 411 GLN F CG    1 
ATOM   10954 C CD    . GLN E 2 429 ? 90.447  192.781 136.636 1.00 55.16  ? 411 GLN F CD    1 
ATOM   10955 O OE1   . GLN E 2 429 ? 91.019  191.863 136.048 1.00 55.16  ? 411 GLN F OE1   1 
ATOM   10956 N NE2   . GLN E 2 429 ? 91.100  193.672 137.376 1.00 55.16  ? 411 GLN F NE2   1 
ATOM   10957 N N     . LYS E 2 430 ? 85.398  191.746 136.906 1.00 53.57  ? 412 LYS F N     1 
ATOM   10958 C CA    . LYS E 2 430 ? 84.613  191.063 135.882 1.00 53.57  ? 412 LYS F CA    1 
ATOM   10959 C C     . LYS E 2 430 ? 83.402  191.886 135.460 1.00 53.57  ? 412 LYS F C     1 
ATOM   10960 O O     . LYS E 2 430 ? 82.994  191.832 134.295 1.00 53.57  ? 412 LYS F O     1 
ATOM   10961 C CB    . LYS E 2 430 ? 84.166  189.690 136.384 1.00 53.57  ? 412 LYS F CB    1 
ATOM   10962 C CG    . LYS E 2 430 ? 85.290  188.669 136.517 1.00 53.57  ? 412 LYS F CG    1 
ATOM   10963 C CD    . LYS E 2 430 ? 85.657  188.029 135.173 1.00 53.57  ? 412 LYS F CD    1 
ATOM   10964 C CE    . LYS E 2 430 ? 84.701  186.914 134.741 1.00 53.57  ? 412 LYS F CE    1 
ATOM   10965 N NZ    . LYS E 2 430 ? 84.601  185.782 135.707 1.00 53.57  ? 412 LYS F NZ    1 
ATOM   10966 N N     . ARG E 2 431 ? 82.822  192.652 136.384 1.00 64.65  ? 413 ARG F N     1 
ATOM   10967 C CA    . ARG E 2 431 ? 81.712  193.546 136.075 1.00 64.65  ? 413 ARG F CA    1 
ATOM   10968 C C     . ARG E 2 431 ? 82.163  194.889 135.497 1.00 64.65  ? 413 ARG F C     1 
ATOM   10969 O O     . ARG E 2 431 ? 81.310  195.743 135.236 1.00 64.65  ? 413 ARG F O     1 
ATOM   10970 C CB    . ARG E 2 431 ? 80.877  193.781 137.341 1.00 64.65  ? 413 ARG F CB    1 
ATOM   10971 C CG    . ARG E 2 431 ? 79.449  194.279 137.088 1.00 64.65  ? 413 ARG F CG    1 
ATOM   10972 C CD    . ARG E 2 431 ? 78.529  194.076 138.288 1.00 64.65  ? 413 ARG F CD    1 
ATOM   10973 N NE    . ARG E 2 431 ? 79.214  194.207 139.570 1.00 64.65  ? 413 ARG F NE    1 
ATOM   10974 C CZ    . ARG E 2 431 ? 79.716  195.333 140.066 1.00 64.65  ? 413 ARG F CZ    1 
ATOM   10975 N NH1   . ARG E 2 431 ? 79.641  196.486 139.415 1.00 64.65  ? 413 ARG F NH1   1 
ATOM   10976 N NH2   . ARG E 2 431 ? 80.312  195.305 141.254 1.00 64.65  ? 413 ARG F NH2   1 
ATOM   10977 N N     . LYS E 2 432 ? 83.468  195.103 135.292 1.00 71.30  ? 414 LYS F N     1 
ATOM   10978 C CA    . LYS E 2 432 ? 84.026  196.372 134.822 1.00 71.30  ? 414 LYS F CA    1 
ATOM   10979 C C     . LYS E 2 432 ? 83.774  197.520 135.796 1.00 71.30  ? 414 LYS F C     1 
ATOM   10980 O O     . LYS E 2 432 ? 83.743  198.684 135.386 1.00 71.30  ? 414 LYS F O     1 
ATOM   10981 C CB    . LYS E 2 432 ? 83.491  196.751 133.433 1.00 71.30  ? 414 LYS F CB    1 
ATOM   10982 C CG    . LYS E 2 432 ? 83.458  195.614 132.426 1.00 71.30  ? 414 LYS F CG    1 
ATOM   10983 C CD    . LYS E 2 432 ? 83.125  196.133 131.036 1.00 71.30  ? 414 LYS F CD    1 
ATOM   10984 C CE    . LYS E 2 432 ? 83.012  195.005 130.026 1.00 71.30  ? 414 LYS F CE    1 
ATOM   10985 N NZ    . LYS E 2 432 ? 81.740  194.248 130.181 1.00 71.30  ? 414 LYS F NZ    1 
ATOM   10986 N N     . GLY E 2 433 ? 83.601  197.220 137.084 1.00 72.07  ? 415 GLY F N     1 
ATOM   10987 C CA    . GLY E 2 433 ? 83.392  198.265 138.065 1.00 72.07  ? 415 GLY F CA    1 
ATOM   10988 C C     . GLY E 2 433 ? 84.693  198.928 138.480 1.00 72.07  ? 415 GLY F C     1 
ATOM   10989 O O     . GLY E 2 433 ? 85.768  198.332 138.433 1.00 72.07  ? 415 GLY F O     1 
ATOM   10990 N N     . LYS E 2 434 ? 84.578  200.191 138.895 1.00 74.97  ? 416 LYS F N     1 
ATOM   10991 C CA    . LYS E 2 434 ? 85.717  200.951 139.398 1.00 74.97  ? 416 LYS F CA    1 
ATOM   10992 C C     . LYS E 2 434 ? 85.939  200.756 140.892 1.00 74.97  ? 416 LYS F C     1 
ATOM   10993 O O     . LYS E 2 434 ? 87.083  200.858 141.352 1.00 74.97  ? 416 LYS F O     1 
ATOM   10994 C CB    . LYS E 2 434 ? 85.531  202.445 139.112 1.00 74.97  ? 416 LYS F CB    1 
ATOM   10995 C CG    . LYS E 2 434 ? 85.983  202.902 137.714 1.00 74.97  ? 416 LYS F CG    1 
ATOM   10996 C CD    . LYS E 2 434 ? 85.227  202.255 136.547 1.00 74.97  ? 416 LYS F CD    1 
ATOM   10997 C CE    . LYS E 2 434 ? 83.734  202.561 136.559 1.00 74.97  ? 416 LYS F CE    1 
ATOM   10998 N NZ    . LYS E 2 434 ? 83.057  202.074 135.326 1.00 74.97  ? 416 LYS F NZ    1 
ATOM   10999 N N     . VAL E 2 435 ? 84.875  200.482 141.650 1.00 70.11  ? 417 VAL F N     1 
ATOM   11000 C CA    . VAL E 2 435 ? 84.929  200.307 143.098 1.00 70.11  ? 417 VAL F CA    1 
ATOM   11001 C C     . VAL E 2 435 ? 84.163  199.039 143.452 1.00 70.11  ? 417 VAL F C     1 
ATOM   11002 O O     . VAL E 2 435 ? 83.063  198.806 142.937 1.00 70.11  ? 417 VAL F O     1 
ATOM   11003 C CB    . VAL E 2 435 ? 84.355  201.531 143.848 1.00 70.11  ? 417 VAL F CB    1 
ATOM   11004 C CG1   . VAL E 2 435 ? 82.858  201.744 143.555 1.00 70.11  ? 417 VAL F CG1   1 
ATOM   11005 C CG2   . VAL E 2 435 ? 84.601  201.421 145.354 1.00 70.11  ? 417 VAL F CG2   1 
ATOM   11006 N N     . VAL E 2 436 ? 84.756  198.214 144.314 1.00 64.05  ? 418 VAL F N     1 
ATOM   11007 C CA    . VAL E 2 436 ? 84.082  197.013 144.795 1.00 64.05  ? 418 VAL F CA    1 
ATOM   11008 C C     . VAL E 2 436 ? 82.892  197.427 145.651 1.00 64.05  ? 418 VAL F C     1 
ATOM   11009 O O     . VAL E 2 436 ? 82.981  198.359 146.462 1.00 64.05  ? 418 VAL F O     1 
ATOM   11010 C CB    . VAL E 2 436 ? 85.078  196.118 145.562 1.00 64.05  ? 418 VAL F CB    1 
ATOM   11011 C CG1   . VAL E 2 436 ? 84.411  195.238 146.647 1.00 64.05  ? 418 VAL F CG1   1 
ATOM   11012 C CG2   . VAL E 2 436 ? 85.839  195.249 144.607 1.00 64.05  ? 418 VAL F CG2   1 
ATOM   11013 N N     . GLU E 2 437 ? 81.776  196.724 145.474 1.00 66.30  ? 419 GLU F N     1 
ATOM   11014 C CA    . GLU E 2 437 ? 80.502  197.012 146.120 1.00 66.30  ? 419 GLU F CA    1 
ATOM   11015 C C     . GLU E 2 437 ? 80.127  195.873 147.060 1.00 66.30  ? 419 GLU F C     1 
ATOM   11016 O O     . GLU E 2 437 ? 80.788  194.834 147.115 1.00 66.30  ? 419 GLU F O     1 
ATOM   11017 C CB    . GLU E 2 437 ? 79.405  197.231 145.070 1.00 66.30  ? 419 GLU F CB    1 
ATOM   11018 C CG    . GLU E 2 437 ? 79.670  198.395 144.119 1.00 66.30  ? 419 GLU F CG    1 
ATOM   11019 C CD    . GLU E 2 437 ? 78.639  198.491 143.014 1.00 66.30  ? 419 GLU F CD    1 
ATOM   11020 O OE1   . GLU E 2 437 ? 77.451  198.715 143.325 1.00 66.30  ? 419 GLU F OE1   1 
ATOM   11021 O OE2   . GLU E 2 437 ? 79.019  198.345 141.833 1.00 66.30  ? 419 GLU F OE2   1 
ATOM   11022 N N     . VAL E 2 438 ? 79.045  196.087 147.813 1.00 62.05  ? 420 VAL F N     1 
ATOM   11023 C CA    . VAL E 2 438 ? 78.603  195.093 148.786 1.00 62.05  ? 420 VAL F CA    1 
ATOM   11024 C C     . VAL E 2 438 ? 78.117  193.819 148.099 1.00 62.05  ? 420 VAL F C     1 
ATOM   11025 O O     . VAL E 2 438 ? 78.218  192.722 148.667 1.00 62.05  ? 420 VAL F O     1 
ATOM   11026 C CB    . VAL E 2 438 ? 77.530  195.712 149.709 1.00 62.05  ? 420 VAL F CB    1 
ATOM   11027 C CG1   . VAL E 2 438 ? 76.113  195.628 149.111 1.00 62.05  ? 420 VAL F CG1   1 
ATOM   11028 C CG2   . VAL E 2 438 ? 77.568  195.051 151.072 1.00 62.05  ? 420 VAL F CG2   1 
ATOM   11029 N N     . GLU E 2 439 ? 77.579  193.935 146.879 1.00 61.76  ? 421 GLU F N     1 
ATOM   11030 C CA    . GLU E 2 439 ? 77.108  192.756 146.162 1.00 61.76  ? 421 GLU F CA    1 
ATOM   11031 C C     . GLU E 2 439 ? 78.258  191.823 145.806 1.00 61.76  ? 421 GLU F C     1 
ATOM   11032 O O     . GLU E 2 439 ? 78.074  190.601 145.789 1.00 61.76  ? 421 GLU F O     1 
ATOM   11033 C CB    . GLU E 2 439 ? 76.331  193.182 144.912 1.00 61.76  ? 421 GLU F CB    1 
ATOM   11034 C CG    . GLU E 2 439 ? 77.165  193.832 143.799 1.00 61.76  ? 421 GLU F CG    1 
ATOM   11035 C CD    . GLU E 2 439 ? 76.315  194.392 142.669 1.00 61.76  ? 421 GLU F CD    1 
ATOM   11036 O OE1   . GLU E 2 439 ? 75.076  194.464 142.817 1.00 61.76  ? 421 GLU F OE1   1 
ATOM   11037 O OE2   . GLU E 2 439 ? 76.891  194.761 141.623 1.00 61.76  ? 421 GLU F OE2   1 
ATOM   11038 N N     . ASP E 2 440 ? 79.444  192.375 145.533 1.00 57.84  ? 422 ASP F N     1 
ATOM   11039 C CA    . ASP E 2 440 ? 80.615  191.538 145.296 1.00 57.84  ? 422 ASP F CA    1 
ATOM   11040 C C     . ASP E 2 440 ? 80.963  190.723 146.533 1.00 57.84  ? 422 ASP F C     1 
ATOM   11041 O O     . ASP E 2 440 ? 81.278  189.531 146.433 1.00 57.84  ? 422 ASP F O     1 
ATOM   11042 C CB    . ASP E 2 440 ? 81.805  192.402 144.883 1.00 57.84  ? 422 ASP F CB    1 
ATOM   11043 C CG    . ASP E 2 440 ? 81.594  193.083 143.550 1.00 57.84  ? 422 ASP F CG    1 
ATOM   11044 O OD1   . ASP E 2 440 ? 81.442  192.372 142.535 1.00 57.84  ? 422 ASP F OD1   1 
ATOM   11045 O OD2   . ASP E 2 440 ? 81.583  194.330 143.516 1.00 57.84  ? 422 ASP F OD2   1 
ATOM   11046 N N     . ILE E 2 441 ? 80.886  191.344 147.712 1.00 54.79  ? 423 ILE F N     1 
ATOM   11047 C CA    . ILE E 2 441 ? 81.215  190.630 148.942 1.00 54.79  ? 423 ILE F CA    1 
ATOM   11048 C C     . ILE E 2 441 ? 80.171  189.557 149.213 1.00 54.79  ? 423 ILE F C     1 
ATOM   11049 O O     . ILE E 2 441 ? 80.505  188.448 149.643 1.00 54.79  ? 423 ILE F O     1 
ATOM   11050 C CB    . ILE E 2 441 ? 81.347  191.596 150.141 1.00 54.79  ? 423 ILE F CB    1 
ATOM   11051 C CG1   . ILE E 2 441 ? 82.197  192.841 149.810 1.00 54.79  ? 423 ILE F CG1   1 
ATOM   11052 C CG2   . ILE E 2 441 ? 81.933  190.856 151.357 1.00 54.79  ? 423 ILE F CG2   1 
ATOM   11053 C CD1   . ILE E 2 441 ? 83.526  192.561 149.160 1.00 54.79  ? 423 ILE F CD1   1 
ATOM   11054 N N     . GLN E 2 442 ? 78.895  189.865 148.960 1.00 52.74  ? 424 GLN F N     1 
ATOM   11055 C CA    . GLN E 2 442 ? 77.833  188.880 149.159 1.00 52.74  ? 424 GLN F CA    1 
ATOM   11056 C C     . GLN E 2 442 ? 78.006  187.686 148.224 1.00 52.74  ? 424 GLN F C     1 
ATOM   11057 O O     . GLN E 2 442 ? 77.899  186.527 148.648 1.00 52.74  ? 424 GLN F O     1 
ATOM   11058 C CB    . GLN E 2 442 ? 76.470  189.537 148.940 1.00 52.74  ? 424 GLN F CB    1 
ATOM   11059 C CG    . GLN E 2 442 ? 76.012  190.431 150.085 1.00 52.74  ? 424 GLN F CG    1 
ATOM   11060 C CD    . GLN E 2 442 ? 75.549  189.653 151.303 1.00 52.74  ? 424 GLN F CD    1 
ATOM   11061 O OE1   . GLN E 2 442 ? 75.454  188.425 151.276 1.00 52.74  ? 424 GLN F OE1   1 
ATOM   11062 N NE2   . GLN E 2 442 ? 75.256  190.369 152.382 1.00 52.74  ? 424 GLN F NE2   1 
ATOM   11063 N N     . ARG E 2 443 ? 78.299  187.959 146.947 1.00 47.54  ? 425 ARG F N     1 
ATOM   11064 C CA    . ARG E 2 443 ? 78.512  186.898 145.966 1.00 47.54  ? 425 ARG F CA    1 
ATOM   11065 C C     . ARG E 2 443 ? 79.698  186.024 146.352 1.00 47.54  ? 425 ARG F C     1 
ATOM   11066 O O     . ARG E 2 443 ? 79.609  184.791 146.333 1.00 47.54  ? 425 ARG F O     1 
ATOM   11067 C CB    . ARG E 2 443 ? 78.730  187.527 144.584 1.00 47.54  ? 425 ARG F CB    1 
ATOM   11068 C CG    . ARG E 2 443 ? 78.929  186.559 143.403 1.00 47.54  ? 425 ARG F CG    1 
ATOM   11069 C CD    . ARG E 2 443 ? 79.339  187.307 142.141 1.00 47.54  ? 425 ARG F CD    1 
ATOM   11070 N NE    . ARG E 2 443 ? 79.706  186.380 141.070 1.00 47.54  ? 425 ARG F NE    1 
ATOM   11071 C CZ    . ARG E 2 443 ? 80.671  186.551 140.168 1.00 47.54  ? 425 ARG F CZ    1 
ATOM   11072 N NH1   . ARG E 2 443 ? 81.385  187.666 140.093 1.00 47.54  ? 425 ARG F NH1   1 
ATOM   11073 N NH2   . ARG E 2 443 ? 80.920  185.574 139.301 1.00 47.54  ? 425 ARG F NH2   1 
ATOM   11074 N N     . VAL E 2 444 ? 80.819  186.648 146.714 1.00 44.83  ? 426 VAL F N     1 
ATOM   11075 C CA    . VAL E 2 444 ? 82.019  185.870 146.989 1.00 44.83  ? 426 VAL F CA    1 
ATOM   11076 C C     . VAL E 2 444 ? 81.863  185.095 148.292 1.00 44.83  ? 426 VAL F C     1 
ATOM   11077 O O     . VAL E 2 444 ? 82.385  183.981 148.421 1.00 44.83  ? 426 VAL F O     1 
ATOM   11078 C CB    . VAL E 2 444 ? 83.246  186.802 146.990 1.00 44.83  ? 426 VAL F CB    1 
ATOM   11079 C CG1   . VAL E 2 444 ? 84.453  186.142 147.639 1.00 44.83  ? 426 VAL F CG1   1 
ATOM   11080 C CG2   . VAL E 2 444 ? 83.569  187.234 145.563 1.00 44.83  ? 426 VAL F CG2   1 
ATOM   11081 N N     . TYR E 2 445 ? 81.163  185.660 149.281 1.00 46.09  ? 427 TYR F N     1 
ATOM   11082 C CA    . TYR E 2 445 ? 80.883  184.910 150.498 1.00 46.09  ? 427 TYR F CA    1 
ATOM   11083 C C     . TYR E 2 445 ? 79.974  183.724 150.218 1.00 46.09  ? 427 TYR F C     1 
ATOM   11084 O O     . TYR E 2 445 ? 80.111  182.677 150.860 1.00 46.09  ? 427 TYR F O     1 
ATOM   11085 C CB    . TYR E 2 445 ? 80.251  185.824 151.547 1.00 46.09  ? 427 TYR F CB    1 
ATOM   11086 C CG    . TYR E 2 445 ? 79.999  185.145 152.873 1.00 46.09  ? 427 TYR F CG    1 
ATOM   11087 C CD1   . TYR E 2 445 ? 81.039  184.906 153.759 1.00 46.09  ? 427 TYR F CD1   1 
ATOM   11088 C CD2   . TYR E 2 445 ? 78.723  184.744 153.239 1.00 46.09  ? 427 TYR F CD2   1 
ATOM   11089 C CE1   . TYR E 2 445 ? 80.817  184.291 154.972 1.00 46.09  ? 427 TYR F CE1   1 
ATOM   11090 C CE2   . TYR E 2 445 ? 78.491  184.124 154.450 1.00 46.09  ? 427 TYR F CE2   1 
ATOM   11091 C CZ    . TYR E 2 445 ? 79.542  183.899 155.313 1.00 46.09  ? 427 TYR F CZ    1 
ATOM   11092 O OH    . TYR E 2 445 ? 79.320  183.283 156.522 1.00 46.09  ? 427 TYR F OH    1 
ATOM   11093 N N     . ARG E 2 446 ? 79.036  183.872 149.280 1.00 43.92  ? 428 ARG F N     1 
ATOM   11094 C CA    . ARG E 2 446 ? 78.235  182.725 148.866 1.00 43.92  ? 428 ARG F CA    1 
ATOM   11095 C C     . ARG E 2 446 ? 79.103  181.661 148.206 1.00 43.92  ? 428 ARG F C     1 
ATOM   11096 O O     . ARG E 2 446 ? 78.930  180.464 148.462 1.00 43.92  ? 428 ARG F O     1 
ATOM   11097 C CB    . ARG E 2 446 ? 77.123  183.180 147.918 1.00 43.92  ? 428 ARG F CB    1 
ATOM   11098 C CG    . ARG E 2 446 ? 76.156  182.080 147.486 1.00 43.92  ? 428 ARG F CG    1 
ATOM   11099 C CD    . ARG E 2 446 ? 75.011  182.642 146.665 1.00 43.92  ? 428 ARG F CD    1 
ATOM   11100 N NE    . ARG E 2 446 ? 75.473  183.224 145.408 1.00 43.92  ? 428 ARG F NE    1 
ATOM   11101 C CZ    . ARG E 2 446 ? 75.809  182.545 144.316 1.00 43.92  ? 428 ARG F CZ    1 
ATOM   11102 N NH1   . ARG E 2 446 ? 75.774  181.220 144.271 1.00 43.92  ? 428 ARG F NH1   1 
ATOM   11103 N NH2   . ARG E 2 446 ? 76.199  183.214 143.235 1.00 43.92  ? 428 ARG F NH2   1 
ATOM   11104 N N     . LEU E 2 447 ? 80.048  182.076 147.360 1.00 39.74  ? 429 LEU F N     1 
ATOM   11105 C CA    . LEU E 2 447 ? 80.831  181.111 146.591 1.00 39.74  ? 429 LEU F CA    1 
ATOM   11106 C C     . LEU E 2 447 ? 81.899  180.437 147.446 1.00 39.74  ? 429 LEU F C     1 
ATOM   11107 O O     . LEU E 2 447 ? 81.860  179.221 147.661 1.00 39.74  ? 429 LEU F O     1 
ATOM   11108 C CB    . LEU E 2 447 ? 81.479  181.800 145.387 1.00 39.74  ? 429 LEU F CB    1 
ATOM   11109 C CG    . LEU E 2 447 ? 80.557  182.322 144.284 1.00 39.74  ? 429 LEU F CG    1 
ATOM   11110 C CD1   . LEU E 2 447 ? 81.353  183.157 143.295 1.00 39.74  ? 429 LEU F CD1   1 
ATOM   11111 C CD2   . LEU E 2 447 ? 79.845  181.184 143.569 1.00 39.74  ? 429 LEU F CD2   1 
ATOM   11112 N N     . PHE E 2 448 ? 82.857  181.214 147.949 1.00 37.32  ? 430 PHE F N     1 
ATOM   11113 C CA    . PHE E 2 448 ? 84.029  180.671 148.632 1.00 37.32  ? 430 PHE F CA    1 
ATOM   11114 C C     . PHE E 2 448 ? 83.680  180.461 150.100 1.00 37.32  ? 430 PHE F C     1 
ATOM   11115 O O     . PHE E 2 448 ? 83.579  181.424 150.865 1.00 37.32  ? 430 PHE F O     1 
ATOM   11116 C CB    . PHE E 2 448 ? 85.233  181.608 148.502 1.00 37.32  ? 430 PHE F CB    1 
ATOM   11117 C CG    . PHE E 2 448 ? 85.778  181.790 147.085 1.00 37.32  ? 430 PHE F CG    1 
ATOM   11118 C CD1   . PHE E 2 448 ? 85.337  181.046 145.991 1.00 37.32  ? 430 PHE F CD1   1 
ATOM   11119 C CD2   . PHE E 2 448 ? 86.765  182.734 146.866 1.00 37.32  ? 430 PHE F CD2   1 
ATOM   11120 C CE1   . PHE E 2 448 ? 85.866  181.254 144.736 1.00 37.32  ? 430 PHE F CE1   1 
ATOM   11121 C CE2   . PHE E 2 448 ? 87.290  182.935 145.608 1.00 37.32  ? 430 PHE F CE2   1 
ATOM   11122 C CZ    . PHE E 2 448 ? 86.840  182.196 144.547 1.00 37.32  ? 430 PHE F CZ    1 
ATOM   11123 N N     . LEU E 2 449 ? 83.507  179.204 150.494 1.00 40.28  ? 431 LEU F N     1 
ATOM   11124 C CA    . LEU E 2 449 ? 83.203  178.898 151.881 1.00 40.28  ? 431 LEU F CA    1 
ATOM   11125 C C     . LEU E 2 449 ? 84.433  179.115 152.755 1.00 40.28  ? 431 LEU F C     1 
ATOM   11126 O O     . LEU E 2 449 ? 85.572  179.120 152.282 1.00 40.28  ? 431 LEU F O     1 
ATOM   11127 C CB    . LEU E 2 449 ? 82.730  177.451 152.029 1.00 40.28  ? 431 LEU F CB    1 
ATOM   11128 C CG    . LEU E 2 449 ? 81.437  176.951 151.368 1.00 40.28  ? 431 LEU F CG    1 
ATOM   11129 C CD1   . LEU E 2 449 ? 80.904  175.749 152.142 1.00 40.28  ? 431 LEU F CD1   1 
ATOM   11130 C CD2   . LEU E 2 449 ? 80.346  178.003 151.233 1.00 40.28  ? 431 LEU F CD2   1 
ATOM   11131 N N     . ASP E 2 450 ? 84.180  179.313 154.047 1.00 44.96  ? 432 ASP F N     1 
ATOM   11132 C CA    . ASP E 2 450 ? 85.218  179.358 155.065 1.00 44.96  ? 432 ASP F CA    1 
ATOM   11133 C C     . ASP E 2 450 ? 85.426  177.959 155.639 1.00 44.96  ? 432 ASP F C     1 
ATOM   11134 O O     . ASP E 2 450 ? 84.807  176.985 155.206 1.00 44.96  ? 432 ASP F O     1 
ATOM   11135 C CB    . ASP E 2 450 ? 84.849  180.350 156.166 1.00 44.96  ? 432 ASP F CB    1 
ATOM   11136 C CG    . ASP E 2 450 ? 83.627  179.925 156.946 1.00 44.96  ? 432 ASP F CG    1 
ATOM   11137 O OD1   . ASP E 2 450 ? 82.503  180.202 156.481 1.00 44.96  ? 432 ASP F OD1   1 
ATOM   11138 O OD2   . ASP E 2 450 ? 83.789  179.312 158.022 1.00 44.96  ? 432 ASP F OD2   1 
ATOM   11139 N N     . VAL E 2 451 ? 86.310  177.853 156.632 1.00 42.67  ? 433 VAL F N     1 
ATOM   11140 C CA    . VAL E 2 451 ? 86.599  176.547 157.217 1.00 42.67  ? 433 VAL F CA    1 
ATOM   11141 C C     . VAL E 2 451 ? 85.418  176.061 158.046 1.00 42.67  ? 433 VAL F C     1 
ATOM   11142 O O     . VAL E 2 451 ? 85.028  174.892 157.962 1.00 42.67  ? 433 VAL F O     1 
ATOM   11143 C CB    . VAL E 2 451 ? 87.895  176.599 158.048 1.00 42.67  ? 433 VAL F CB    1 
ATOM   11144 C CG1   . VAL E 2 451 ? 88.272  175.191 158.546 1.00 42.67  ? 433 VAL F CG1   1 
ATOM   11145 C CG2   . VAL E 2 451 ? 89.030  177.222 157.222 1.00 42.67  ? 433 VAL F CG2   1 
ATOM   11146 N N     . ARG E 2 452 ? 84.827  176.943 158.857 1.00 47.43  ? 434 ARG F N     1 
ATOM   11147 C CA    . ARG E 2 452 ? 83.761  176.519 159.764 1.00 47.43  ? 434 ARG F CA    1 
ATOM   11148 C C     . ARG E 2 452 ? 82.495  176.141 159.005 1.00 47.43  ? 434 ARG F C     1 
ATOM   11149 O O     . ARG E 2 452 ? 81.857  175.128 159.314 1.00 47.43  ? 434 ARG F O     1 
ATOM   11150 C CB    . ARG E 2 452 ? 83.464  177.628 160.774 1.00 47.43  ? 434 ARG F CB    1 
ATOM   11151 C CG    . ARG E 2 452 ? 82.824  177.136 162.062 1.00 47.43  ? 434 ARG F CG    1 
ATOM   11152 C CD    . ARG E 2 452 ? 81.995  178.226 162.726 1.00 47.43  ? 434 ARG F CD    1 
ATOM   11153 N NE    . ARG E 2 452 ? 80.721  178.451 162.047 1.00 47.43  ? 434 ARG F NE    1 
ATOM   11154 C CZ    . ARG E 2 452 ? 79.670  177.638 162.081 1.00 47.43  ? 434 ARG F CZ    1 
ATOM   11155 N NH1   . ARG E 2 452 ? 79.677  176.506 162.772 1.00 47.43  ? 434 ARG F NH1   1 
ATOM   11156 N NH2   . ARG E 2 452 ? 78.575  177.971 161.403 1.00 47.43  ? 434 ARG F NH2   1 
ATOM   11157 N N     . ARG E 2 453 ? 82.113  176.946 158.013 1.00 43.80  ? 435 ARG F N     1 
ATOM   11158 C CA    . ARG E 2 453 ? 80.897  176.671 157.257 1.00 43.80  ? 435 ARG F CA    1 
ATOM   11159 C C     . ARG E 2 453 ? 81.034  175.396 156.435 1.00 43.80  ? 435 ARG F C     1 
ATOM   11160 O O     . ARG E 2 453 ? 80.097  174.592 156.366 1.00 43.80  ? 435 ARG F O     1 
ATOM   11161 C CB    . ARG E 2 453 ? 80.577  177.866 156.363 1.00 43.80  ? 435 ARG F CB    1 
ATOM   11162 C CG    . ARG E 2 453 ? 79.293  177.745 155.564 1.00 43.80  ? 435 ARG F CG    1 
ATOM   11163 C CD    . ARG E 2 453 ? 78.811  179.090 155.004 1.00 43.80  ? 435 ARG F CD    1 
ATOM   11164 N NE    . ARG E 2 453 ? 79.907  180.013 154.690 1.00 43.80  ? 435 ARG F NE    1 
ATOM   11165 C CZ    . ARG E 2 453 ? 80.028  180.769 153.601 1.00 43.80  ? 435 ARG F CZ    1 
ATOM   11166 N NH1   . ARG E 2 453 ? 79.079  180.846 152.676 1.00 43.80  ? 435 ARG F NH1   1 
ATOM   11167 N NH2   . ARG E 2 453 ? 81.135  181.487 153.438 1.00 43.80  ? 435 ARG F NH2   1 
ATOM   11168 N N     . SER E 2 454 ? 82.196  175.186 155.815 1.00 43.21  ? 436 SER F N     1 
ATOM   11169 C CA    . SER E 2 454 ? 82.414  173.960 155.055 1.00 43.21  ? 436 SER F CA    1 
ATOM   11170 C C     . SER E 2 454 ? 82.498  172.750 155.974 1.00 43.21  ? 436 SER F C     1 
ATOM   11171 O O     . SER E 2 454 ? 82.046  171.658 155.613 1.00 43.21  ? 436 SER F O     1 
ATOM   11172 C CB    . SER E 2 454 ? 83.680  174.085 154.217 1.00 43.21  ? 436 SER F CB    1 
ATOM   11173 O OG    . SER E 2 454 ? 83.972  172.875 153.545 1.00 43.21  ? 436 SER F OG    1 
ATOM   11174 N N     . MET E 2 455 ? 83.078  172.927 157.162 1.00 51.14  ? 437 MET F N     1 
ATOM   11175 C CA    . MET E 2 455 ? 83.101  171.872 158.168 1.00 51.14  ? 437 MET F CA    1 
ATOM   11176 C C     . MET E 2 455 ? 81.683  171.470 158.558 1.00 51.14  ? 437 MET F C     1 
ATOM   11177 O O     . MET E 2 455 ? 81.360  170.277 158.646 1.00 51.14  ? 437 MET F O     1 
ATOM   11178 C CB    . MET E 2 455 ? 83.879  172.383 159.382 1.00 51.14  ? 437 MET F CB    1 
ATOM   11179 C CG    . MET E 2 455 ? 84.067  171.440 160.550 1.00 51.14  ? 437 MET F CG    1 
ATOM   11180 S SD    . MET E 2 455 ? 84.837  169.874 160.134 1.00 51.14  ? 437 MET F SD    1 
ATOM   11181 C CE    . MET E 2 455 ? 85.725  169.587 161.658 1.00 51.14  ? 437 MET F CE    1 
ATOM   11182 N N     . GLN E 2 456 ? 80.821  172.468 158.774 1.00 51.41  ? 438 GLN F N     1 
ATOM   11183 C CA    . GLN E 2 456 ? 79.418  172.219 159.091 1.00 51.41  ? 438 GLN F CA    1 
ATOM   11184 C C     . GLN E 2 456 ? 78.727  171.489 157.944 1.00 51.41  ? 438 GLN F C     1 
ATOM   11185 O O     . GLN E 2 456 ? 78.007  170.505 158.156 1.00 51.41  ? 438 GLN F O     1 
ATOM   11186 C CB    . GLN E 2 456 ? 78.730  173.559 159.394 1.00 51.41  ? 438 GLN F CB    1 
ATOM   11187 C CG    . GLN E 2 456 ? 77.228  173.541 159.748 1.00 51.41  ? 438 GLN F CG    1 
ATOM   11188 C CD    . GLN E 2 456 ? 76.988  173.353 161.230 1.00 51.41  ? 438 GLN F CD    1 
ATOM   11189 O OE1   . GLN E 2 456 ? 77.628  172.521 161.873 1.00 51.41  ? 438 GLN F OE1   1 
ATOM   11190 N NE2   . GLN E 2 456 ? 76.059  174.126 161.784 1.00 51.41  ? 438 GLN F NE2   1 
ATOM   11191 N N     . TYR E 2 457 ? 78.936  171.960 156.716 1.00 48.97  ? 439 TYR F N     1 
ATOM   11192 C CA    . TYR E 2 457 ? 78.254  171.367 155.573 1.00 48.97  ? 439 TYR F CA    1 
ATOM   11193 C C     . TYR E 2 457 ? 78.770  169.970 155.248 1.00 48.97  ? 439 TYR F C     1 
ATOM   11194 O O     . TYR E 2 457 ? 78.042  169.195 154.620 1.00 48.97  ? 439 TYR F O     1 
ATOM   11195 C CB    . TYR E 2 457 ? 78.391  172.279 154.346 1.00 48.97  ? 439 TYR F CB    1 
ATOM   11196 C CG    . TYR E 2 457 ? 77.401  173.438 154.269 1.00 48.97  ? 439 TYR F CG    1 
ATOM   11197 C CD1   . TYR E 2 457 ? 76.903  174.054 155.416 1.00 48.97  ? 439 TYR F CD1   1 
ATOM   11198 C CD2   . TYR E 2 457 ? 76.966  173.913 153.039 1.00 48.97  ? 439 TYR F CD2   1 
ATOM   11199 C CE1   . TYR E 2 457 ? 76.006  175.100 155.336 1.00 48.97  ? 439 TYR F CE1   1 
ATOM   11200 C CE2   . TYR E 2 457 ? 76.068  174.960 152.951 1.00 48.97  ? 439 TYR F CE2   1 
ATOM   11201 C CZ    . TYR E 2 457 ? 75.592  175.549 154.103 1.00 48.97  ? 439 TYR F CZ    1 
ATOM   11202 O OH    . TYR E 2 457 ? 74.699  176.592 154.020 1.00 48.97  ? 439 TYR F OH    1 
ATOM   11203 N N     . LEU E 2 458 ? 79.999  169.634 155.659 1.00 47.66  ? 440 LEU F N     1 
ATOM   11204 C CA    . LEU E 2 458 ? 80.522  168.285 155.450 1.00 47.66  ? 440 LEU F CA    1 
ATOM   11205 C C     . LEU E 2 458 ? 80.061  167.322 156.537 1.00 47.66  ? 440 LEU F C     1 
ATOM   11206 O O     . LEU E 2 458 ? 79.737  166.168 156.235 1.00 47.66  ? 440 LEU F O     1 
ATOM   11207 C CB    . LEU E 2 458 ? 82.053  168.302 155.380 1.00 47.66  ? 440 LEU F CB    1 
ATOM   11208 C CG    . LEU E 2 458 ? 82.702  168.283 153.990 1.00 47.66  ? 440 LEU F CG    1 
ATOM   11209 C CD1   . LEU E 2 458 ? 82.574  166.914 153.344 1.00 47.66  ? 440 LEU F CD1   1 
ATOM   11210 C CD2   . LEU E 2 458 ? 82.128  169.353 153.072 1.00 47.66  ? 440 LEU F CD2   1 
ATOM   11211 N N     . VAL E 2 459 ? 80.036  167.758 157.803 1.00 55.49  ? 441 VAL F N     1 
ATOM   11212 C CA    . VAL E 2 459 ? 79.518  166.865 158.841 1.00 55.49  ? 441 VAL F CA    1 
ATOM   11213 C C     . VAL E 2 459 ? 78.021  166.645 158.649 1.00 55.49  ? 441 VAL F C     1 
ATOM   11214 O O     . VAL E 2 459 ? 77.517  165.542 158.897 1.00 55.49  ? 441 VAL F O     1 
ATOM   11215 C CB    . VAL E 2 459 ? 79.839  167.370 160.266 1.00 55.49  ? 441 VAL F CB    1 
ATOM   11216 C CG1   . VAL E 2 459 ? 81.350  167.430 160.484 1.00 55.49  ? 441 VAL F CG1   1 
ATOM   11217 C CG2   . VAL E 2 459 ? 79.179  168.706 160.584 1.00 55.49  ? 441 VAL F CG2   1 
ATOM   11218 N N     . GLU E 2 460 ? 77.290  167.664 158.174 1.00 59.25  ? 442 GLU F N     1 
ATOM   11219 C CA    . GLU E 2 460 ? 75.862  167.499 157.908 1.00 59.25  ? 442 GLU F CA    1 
ATOM   11220 C C     . GLU E 2 460 ? 75.575  166.508 156.785 1.00 59.25  ? 442 GLU F C     1 
ATOM   11221 O O     . GLU E 2 460 ? 74.438  166.035 156.683 1.00 59.25  ? 442 GLU F O     1 
ATOM   11222 C CB    . GLU E 2 460 ? 75.213  168.843 157.561 1.00 59.25  ? 442 GLU F CB    1 
ATOM   11223 C CG    . GLU E 2 460 ? 74.597  169.561 158.748 1.00 59.25  ? 442 GLU F CG    1 
ATOM   11224 C CD    . GLU E 2 460 ? 73.890  170.842 158.346 1.00 59.25  ? 442 GLU F CD    1 
ATOM   11225 O OE1   . GLU E 2 460 ? 74.552  171.900 158.311 1.00 59.25  ? 442 GLU F OE1   1 
ATOM   11226 O OE2   . GLU E 2 460 ? 72.676  170.790 158.057 1.00 59.25  ? 442 GLU F OE2   1 
ATOM   11227 N N     . TYR E 2 461 ? 76.553  166.213 155.924 1.00 53.87  ? 443 TYR F N     1 
ATOM   11228 C CA    . TYR E 2 461 ? 76.446  165.095 154.992 1.00 53.87  ? 443 TYR F CA    1 
ATOM   11229 C C     . TYR E 2 461 ? 76.883  163.791 155.653 1.00 53.87  ? 443 TYR F C     1 
ATOM   11230 O O     . TYR E 2 461 ? 76.174  162.783 155.576 1.00 53.87  ? 443 TYR F O     1 
ATOM   11231 C CB    . TYR E 2 461 ? 77.282  165.355 153.725 1.00 53.87  ? 443 TYR F CB    1 
ATOM   11232 C CG    . TYR E 2 461 ? 77.929  164.112 153.136 1.00 53.87  ? 443 TYR F CG    1 
ATOM   11233 C CD1   . TYR E 2 461 ? 77.188  163.199 152.393 1.00 53.87  ? 443 TYR F CD1   1 
ATOM   11234 C CD2   . TYR E 2 461 ? 79.284  163.858 153.319 1.00 53.87  ? 443 TYR F CD2   1 
ATOM   11235 C CE1   . TYR E 2 461 ? 77.772  162.065 151.868 1.00 53.87  ? 443 TYR F CE1   1 
ATOM   11236 C CE2   . TYR E 2 461 ? 79.876  162.727 152.793 1.00 53.87  ? 443 TYR F CE2   1 
ATOM   11237 C CZ    . TYR E 2 461 ? 79.117  161.837 152.067 1.00 53.87  ? 443 TYR F CZ    1 
ATOM   11238 O OH    . TYR E 2 461 ? 79.707  160.712 151.541 1.00 53.87  ? 443 TYR F OH    1 
ATOM   11239 N N     . GLN E 2 462 ? 78.043  163.797 156.312 1.00 59.12  ? 444 GLN F N     1 
ATOM   11240 C CA    . GLN E 2 462 ? 78.672  162.536 156.684 1.00 59.12  ? 444 GLN F CA    1 
ATOM   11241 C C     . GLN E 2 462 ? 77.974  161.853 157.852 1.00 59.12  ? 444 GLN F C     1 
ATOM   11242 O O     . GLN E 2 462 ? 77.943  160.619 157.904 1.00 59.12  ? 444 GLN F O     1 
ATOM   11243 C CB    . GLN E 2 462 ? 80.147  162.757 157.017 1.00 59.12  ? 444 GLN F CB    1 
ATOM   11244 C CG    . GLN E 2 462 ? 81.011  161.539 156.712 1.00 59.12  ? 444 GLN F CG    1 
ATOM   11245 C CD    . GLN E 2 462 ? 82.411  161.634 157.284 1.00 59.12  ? 444 GLN F CD    1 
ATOM   11246 O OE1   . GLN E 2 462 ? 82.638  162.279 158.308 1.00 59.12  ? 444 GLN F OE1   1 
ATOM   11247 N NE2   . GLN E 2 462 ? 83.359  160.978 156.626 1.00 59.12  ? 444 GLN F NE2   1 
ATOM   11248 N N     . SER E 2 463 ? 77.420  162.617 158.798 1.00 67.59  ? 445 SER F N     1 
ATOM   11249 C CA    . SER E 2 463 ? 76.764  161.993 159.942 1.00 67.59  ? 445 SER F CA    1 
ATOM   11250 C C     . SER E 2 463 ? 75.478  161.283 159.529 1.00 67.59  ? 445 SER F C     1 
ATOM   11251 O O     . SER E 2 463 ? 75.187  160.186 160.021 1.00 67.59  ? 445 SER F O     1 
ATOM   11252 C CB    . SER E 2 463 ? 76.491  163.039 161.025 1.00 67.59  ? 445 SER F CB    1 
ATOM   11253 O OG    . SER E 2 463 ? 75.658  162.517 162.044 1.00 67.59  ? 445 SER F OG    1 
ATOM   11254 N N     . GLN E 2 464 ? 74.703  161.881 158.621 1.00 68.72  ? 446 GLN F N     1 
ATOM   11255 C CA    . GLN E 2 464 ? 73.422  161.316 158.196 1.00 68.72  ? 446 GLN F CA    1 
ATOM   11256 C C     . GLN E 2 464 ? 73.591  160.283 157.082 1.00 68.72  ? 446 GLN F C     1 
ATOM   11257 O O     . GLN E 2 464 ? 73.177  159.129 157.233 1.00 68.72  ? 446 GLN F O     1 
ATOM   11258 C CB    . GLN E 2 464 ? 72.441  162.413 157.735 1.00 68.72  ? 446 GLN F CB    1 
ATOM   11259 C CG    . GLN E 2 464 ? 72.088  163.535 158.742 1.00 68.72  ? 446 GLN F CG    1 
ATOM   11260 C CD    . GLN E 2 464 ? 73.180  164.559 158.962 1.00 68.72  ? 446 GLN F CD    1 
ATOM   11261 O OE1   . GLN E 2 464 ? 74.364  164.247 158.855 1.00 68.72  ? 446 GLN F OE1   1 
ATOM   11262 N NE2   . GLN E 2 464 ? 72.788  165.789 159.269 1.00 68.72  ? 446 GLN F NE2   1 
ATOM   11263 N N     . TYR E 2 465 ? 74.198  160.678 155.963 1.00 68.41  ? 447 TYR F N     1 
ATOM   11264 C CA    . TYR E 2 465 ? 74.238  159.823 154.780 1.00 68.41  ? 447 TYR F CA    1 
ATOM   11265 C C     . TYR E 2 465 ? 75.226  158.662 154.885 1.00 68.41  ? 447 TYR F C     1 
ATOM   11266 O O     . TYR E 2 465 ? 75.269  157.842 153.960 1.00 68.41  ? 447 TYR F O     1 
ATOM   11267 C CB    . TYR E 2 465 ? 74.570  160.658 153.539 1.00 68.41  ? 447 TYR F CB    1 
ATOM   11268 C CG    . TYR E 2 465 ? 73.417  161.499 153.036 1.00 68.41  ? 447 TYR F CG    1 
ATOM   11269 C CD1   . TYR E 2 465 ? 73.045  162.669 153.684 1.00 68.41  ? 447 TYR F CD1   1 
ATOM   11270 C CD2   . TYR E 2 465 ? 72.694  161.114 151.914 1.00 68.41  ? 447 TYR F CD2   1 
ATOM   11271 C CE1   . TYR E 2 465 ? 71.991  163.436 153.223 1.00 68.41  ? 447 TYR F CE1   1 
ATOM   11272 C CE2   . TYR E 2 465 ? 71.640  161.873 151.448 1.00 68.41  ? 447 TYR F CE2   1 
ATOM   11273 C CZ    . TYR E 2 465 ? 71.292  163.032 152.106 1.00 68.41  ? 447 TYR F CZ    1 
ATOM   11274 O OH    . TYR E 2 465 ? 70.240  163.789 151.642 1.00 68.41  ? 447 TYR F OH    1 
ATOM   11275 N N     . MET E 2 466 ? 76.018  158.574 155.955 1.00 67.04  ? 448 MET F N     1 
ATOM   11276 C CA    . MET E 2 466 ? 76.935  157.451 156.173 1.00 67.04  ? 448 MET F CA    1 
ATOM   11277 C C     . MET E 2 466 ? 76.899  157.021 157.634 1.00 67.04  ? 448 MET F C     1 
ATOM   11278 O O     . MET E 2 466 ? 76.456  157.768 158.505 1.00 67.04  ? 448 MET F O     1 
ATOM   11279 C CB    . MET E 2 466 ? 78.360  157.832 155.772 1.00 67.04  ? 448 MET F CB    1 
ATOM   11280 C CG    . MET E 2 466 ? 79.193  156.667 155.256 1.00 67.04  ? 448 MET F CG    1 
ATOM   11281 S SD    . MET E 2 466 ? 78.979  156.377 153.491 1.00 67.04  ? 448 MET F SD    1 
ATOM   11282 C CE    . MET E 2 466 ? 80.229  157.469 152.816 1.00 67.04  ? 448 MET F CE    1 
ATOM   11283 N N     . GLN F 2 63  ? 78.543  127.480 141.290 1.00 51.15  ? 45  GLN E N     1 
ATOM   11284 C CA    . GLN F 2 63  ? 78.413  128.933 140.988 1.00 51.15  ? 45  GLN E CA    1 
ATOM   11285 C C     . GLN F 2 63  ? 77.701  129.127 139.656 1.00 51.15  ? 45  GLN E C     1 
ATOM   11286 O O     . GLN F 2 63  ? 77.973  128.402 138.697 1.00 51.15  ? 45  GLN E O     1 
ATOM   11287 C CB    . GLN F 2 63  ? 79.791  129.601 140.948 1.00 51.15  ? 45  GLN E CB    1 
ATOM   11288 C CG    . GLN F 2 63  ? 80.590  129.520 142.247 1.00 51.15  ? 45  GLN E CG    1 
ATOM   11289 C CD    . GLN F 2 63  ? 79.893  130.176 143.423 1.00 51.15  ? 45  GLN E CD    1 
ATOM   11290 O OE1   . GLN F 2 63  ? 79.504  131.340 143.355 1.00 51.15  ? 45  GLN E OE1   1 
ATOM   11291 N NE2   . GLN F 2 63  ? 79.732  129.431 144.510 1.00 51.15  ? 45  GLN E NE2   1 
ATOM   11292 N N     . VAL F 2 64  ? 76.792  130.105 139.613 1.00 48.93  ? 46  VAL E N     1 
ATOM   11293 C CA    . VAL F 2 64  ? 76.005  130.417 138.421 1.00 48.93  ? 46  VAL E CA    1 
ATOM   11294 C C     . VAL F 2 64  ? 76.158  131.902 138.114 1.00 48.93  ? 46  VAL E C     1 
ATOM   11295 O O     . VAL F 2 64  ? 76.600  132.276 137.022 1.00 48.93  ? 46  VAL E O     1 
ATOM   11296 C CB    . VAL F 2 64  ? 74.526  130.028 138.619 1.00 48.93  ? 46  VAL E CB    1 
ATOM   11297 C CG1   . VAL F 2 64  ? 73.630  130.635 137.527 1.00 48.93  ? 46  VAL E CG1   1 
ATOM   11298 C CG2   . VAL F 2 64  ? 74.374  128.510 138.658 1.00 48.93  ? 46  VAL E CG2   1 
ATOM   11299 N N     . LYS F 2 65  ? 75.789  132.758 139.070 1.00 50.18  ? 47  LYS E N     1 
ATOM   11300 C CA    . LYS F 2 65  ? 75.860  134.196 138.831 1.00 50.18  ? 47  LYS E CA    1 
ATOM   11301 C C     . LYS F 2 65  ? 77.303  134.673 138.735 1.00 50.18  ? 47  LYS E C     1 
ATOM   11302 O O     . LYS F 2 65  ? 77.622  135.538 137.910 1.00 50.18  ? 47  LYS E O     1 
ATOM   11303 C CB    . LYS F 2 65  ? 75.118  134.955 139.931 1.00 50.18  ? 47  LYS E CB    1 
ATOM   11304 C CG    . LYS F 2 65  ? 73.594  134.817 139.854 1.00 50.18  ? 47  LYS E CG    1 
ATOM   11305 C CD    . LYS F 2 65  ? 72.859  135.367 141.090 1.00 50.18  ? 47  LYS E CD    1 
ATOM   11306 C CE    . LYS F 2 65  ? 73.127  134.607 142.395 1.00 50.18  ? 47  LYS E CE    1 
ATOM   11307 N NZ    . LYS F 2 65  ? 73.031  133.124 142.276 1.00 50.18  ? 47  LYS E NZ    1 
ATOM   11308 N N     . ALA F 2 66  ? 78.188  134.129 139.575 1.00 47.19  ? 48  ALA E N     1 
ATOM   11309 C CA    . ALA F 2 66  ? 79.590  134.529 139.533 1.00 47.19  ? 48  ALA E CA    1 
ATOM   11310 C C     . ALA F 2 66  ? 80.239  134.126 138.215 1.00 47.19  ? 48  ALA E C     1 
ATOM   11311 O O     . ALA F 2 66  ? 81.033  134.885 137.647 1.00 47.19  ? 48  ALA E O     1 
ATOM   11312 C CB    . ALA F 2 66  ? 80.345  133.915 140.710 1.00 47.19  ? 48  ALA E CB    1 
ATOM   11313 N N     . ARG F 2 67  ? 79.908  132.938 137.709 1.00 47.72  ? 49  ARG E N     1 
ATOM   11314 C CA    . ARG F 2 67  ? 80.471  132.500 136.437 1.00 47.72  ? 49  ARG E CA    1 
ATOM   11315 C C     . ARG F 2 67  ? 79.945  133.343 135.282 1.00 47.72  ? 49  ARG E C     1 
ATOM   11316 O O     . ARG F 2 67  ? 80.686  133.646 134.341 1.00 47.72  ? 49  ARG E O     1 
ATOM   11317 C CB    . ARG F 2 67  ? 80.165  131.019 136.218 1.00 47.72  ? 49  ARG E CB    1 
ATOM   11318 C CG    . ARG F 2 67  ? 80.910  130.108 137.181 1.00 47.72  ? 49  ARG E CG    1 
ATOM   11319 C CD    . ARG F 2 67  ? 80.719  128.639 136.850 1.00 47.72  ? 49  ARG E CD    1 
ATOM   11320 N NE    . ARG F 2 67  ? 81.951  128.031 136.354 1.00 47.72  ? 49  ARG E NE    1 
ATOM   11321 C CZ    . ARG F 2 67  ? 82.974  127.632 137.103 1.00 47.72  ? 49  ARG E CZ    1 
ATOM   11322 N NH1   . ARG F 2 67  ? 82.979  127.770 138.422 1.00 47.72  ? 49  ARG E NH1   1 
ATOM   11323 N NH2   . ARG F 2 67  ? 84.031  127.083 136.511 1.00 47.72  ? 49  ARG E NH2   1 
ATOM   11324 N N     . LYS F 2 68  ? 78.670  133.739 135.335 1.00 46.74  ? 50  LYS E N     1 
ATOM   11325 C CA    . LYS F 2 68  ? 78.135  134.627 134.307 1.00 46.74  ? 50  LYS E CA    1 
ATOM   11326 C C     . LYS F 2 68  ? 78.805  135.994 134.355 1.00 46.74  ? 50  LYS E C     1 
ATOM   11327 O O     . LYS F 2 68  ? 79.090  136.591 133.308 1.00 46.74  ? 50  LYS E O     1 
ATOM   11328 C CB    . LYS F 2 68  ? 76.624  134.770 134.466 1.00 46.74  ? 50  LYS E CB    1 
ATOM   11329 C CG    . LYS F 2 68  ? 75.985  135.649 133.404 1.00 46.74  ? 50  LYS E CG    1 
ATOM   11330 C CD    . LYS F 2 68  ? 74.535  135.272 133.145 1.00 46.74  ? 50  LYS E CD    1 
ATOM   11331 C CE    . LYS F 2 68  ? 73.696  135.345 134.407 1.00 46.74  ? 50  LYS E CE    1 
ATOM   11332 N NZ    . LYS F 2 68  ? 72.248  135.452 134.090 1.00 46.74  ? 50  LYS E NZ    1 
ATOM   11333 N N     . ALA F 2 69  ? 79.058  136.508 135.562 1.00 46.25  ? 51  ALA E N     1 
ATOM   11334 C CA    . ALA F 2 69  ? 79.794  137.761 135.696 1.00 46.25  ? 51  ALA E CA    1 
ATOM   11335 C C     . ALA F 2 69  ? 81.200  137.633 135.127 1.00 46.25  ? 51  ALA E C     1 
ATOM   11336 O O     . ALA F 2 69  ? 81.688  138.543 134.445 1.00 46.25  ? 51  ALA E O     1 
ATOM   11337 C CB    . ALA F 2 69  ? 79.854  138.182 137.162 1.00 46.25  ? 51  ALA E CB    1 
ATOM   11338 N N     . ALA F 2 70  ? 81.863  136.507 135.396 1.00 46.01  ? 52  ALA E N     1 
ATOM   11339 C CA    . ALA F 2 70  ? 83.189  136.273 134.836 1.00 46.01  ? 52  ALA E CA    1 
ATOM   11340 C C     . ALA F 2 70  ? 83.139  136.198 133.316 1.00 46.01  ? 52  ALA E C     1 
ATOM   11341 O O     . ALA F 2 70  ? 84.059  136.657 132.638 1.00 46.01  ? 52  ALA E O     1 
ATOM   11342 C CB    . ALA F 2 70  ? 83.787  134.994 135.419 1.00 46.01  ? 52  ALA E CB    1 
ATOM   11343 N N     . GLY F 2 71  ? 82.065  135.635 132.761 1.00 48.19  ? 53  GLY E N     1 
ATOM   11344 C CA    . GLY F 2 71  ? 81.915  135.623 131.314 1.00 48.19  ? 53  GLY E CA    1 
ATOM   11345 C C     . GLY F 2 71  ? 81.731  137.013 130.731 1.00 48.19  ? 53  GLY E C     1 
ATOM   11346 O O     . GLY F 2 71  ? 82.264  137.326 129.659 1.00 48.19  ? 53  GLY E O     1 
ATOM   11347 N N     . VAL F 2 72  ? 80.963  137.862 131.420 1.00 46.68  ? 54  VAL E N     1 
ATOM   11348 C CA    . VAL F 2 72  ? 80.778  139.237 130.955 1.00 46.68  ? 54  VAL E CA    1 
ATOM   11349 C C     . VAL F 2 72  ? 82.102  139.993 130.995 1.00 46.68  ? 54  VAL E C     1 
ATOM   11350 O O     . VAL F 2 72  ? 82.445  140.725 130.055 1.00 46.68  ? 54  VAL E O     1 
ATOM   11351 C CB    . VAL F 2 72  ? 79.683  139.941 131.783 1.00 46.68  ? 54  VAL E CB    1 
ATOM   11352 C CG1   . VAL F 2 72  ? 79.645  141.445 131.486 1.00 46.68  ? 54  VAL E CG1   1 
ATOM   11353 C CG2   . VAL F 2 72  ? 78.320  139.324 131.487 1.00 46.68  ? 54  VAL E CG2   1 
ATOM   11354 N N     . ILE F 2 73  ? 82.876  139.819 132.071 1.00 47.76  ? 55  ILE E N     1 
ATOM   11355 C CA    . ILE F 2 73  ? 84.197  140.446 132.126 1.00 47.76  ? 55  ILE E CA    1 
ATOM   11356 C C     . ILE F 2 73  ? 85.102  139.855 131.052 1.00 47.76  ? 55  ILE E C     1 
ATOM   11357 O O     . ILE F 2 73  ? 85.952  140.567 130.512 1.00 47.76  ? 55  ILE E O     1 
ATOM   11358 C CB    . ILE F 2 73  ? 84.823  140.331 133.537 1.00 47.76  ? 55  ILE E CB    1 
ATOM   11359 C CG1   . ILE F 2 73  ? 83.940  141.031 134.576 1.00 47.76  ? 55  ILE E CG1   1 
ATOM   11360 C CG2   . ILE F 2 73  ? 86.257  140.980 133.653 1.00 47.76  ? 55  ILE E CG2   1 
ATOM   11361 C CD1   . ILE F 2 73  ? 84.485  141.002 135.993 1.00 47.76  ? 55  ILE E CD1   1 
ATOM   11362 N N     . LEU F 2 74  ? 84.970  138.558 130.753 1.00 49.87  ? 56  LEU E N     1 
ATOM   11363 C CA    . LEU F 2 74  ? 85.788  137.939 129.713 1.00 49.87  ? 56  LEU E CA    1 
ATOM   11364 C C     . LEU F 2 74  ? 85.525  138.578 128.358 1.00 49.87  ? 56  LEU E C     1 
ATOM   11365 O O     . LEU F 2 74  ? 86.462  138.903 127.617 1.00 49.87  ? 56  LEU E O     1 
ATOM   11366 C CB    . LEU F 2 74  ? 85.526  136.435 129.653 1.00 49.87  ? 56  LEU E CB    1 
ATOM   11367 C CG    . LEU F 2 74  ? 86.267  135.588 130.684 1.00 49.87  ? 56  LEU E CG    1 
ATOM   11368 C CD1   . LEU F 2 74  ? 85.543  134.277 130.931 1.00 49.87  ? 56  LEU E CD1   1 
ATOM   11369 C CD2   . LEU F 2 74  ? 87.678  135.328 130.192 1.00 49.87  ? 56  LEU E CD2   1 
ATOM   11370 N N     . GLN F 2 75  ? 84.250  138.782 128.029 1.00 50.11  ? 57  GLN E N     1 
ATOM   11371 C CA    . GLN F 2 75  ? 83.920  139.507 126.807 1.00 50.11  ? 57  GLN E CA    1 
ATOM   11372 C C     . GLN F 2 75  ? 84.418  140.945 126.862 1.00 50.11  ? 57  GLN E C     1 
ATOM   11373 O O     . GLN F 2 75  ? 84.780  141.513 125.826 1.00 50.11  ? 57  GLN E O     1 
ATOM   11374 C CB    . GLN F 2 75  ? 82.412  139.484 126.561 1.00 50.11  ? 57  GLN E CB    1 
ATOM   11375 C CG    . GLN F 2 75  ? 81.912  138.255 125.822 1.00 50.11  ? 57  GLN E CG    1 
ATOM   11376 C CD    . GLN F 2 75  ? 82.298  138.248 124.357 1.00 50.11  ? 57  GLN E CD    1 
ATOM   11377 O OE1   . GLN F 2 75  ? 83.184  137.502 123.940 1.00 50.11  ? 57  GLN E OE1   1 
ATOM   11378 N NE2   . GLN F 2 75  ? 81.642  139.088 123.569 1.00 50.11  ? 57  GLN E NE2   1 
ATOM   11379 N N     . MET F 2 76  ? 84.448  141.549 128.051 1.00 49.46  ? 58  MET E N     1 
ATOM   11380 C CA    . MET F 2 76  ? 84.943  142.918 128.157 1.00 49.46  ? 58  MET E CA    1 
ATOM   11381 C C     . MET F 2 76  ? 86.440  143.005 127.864 1.00 49.46  ? 58  MET E C     1 
ATOM   11382 O O     . MET F 2 76  ? 86.875  143.893 127.122 1.00 49.46  ? 58  MET E O     1 
ATOM   11383 C CB    . MET F 2 76  ? 84.628  143.473 129.544 1.00 49.46  ? 58  MET E CB    1 
ATOM   11384 C CG    . MET F 2 76  ? 84.810  144.988 129.664 1.00 49.46  ? 58  MET E CG    1 
ATOM   11385 S SD    . MET F 2 76  ? 83.909  145.879 130.966 1.00 49.46  ? 58  MET E SD    1 
ATOM   11386 C CE    . MET F 2 76  ? 83.374  144.601 132.103 1.00 49.46  ? 58  MET E CE    1 
ATOM   11387 N N     . ILE F 2 77  ? 87.246  142.102 128.437 1.00 49.76  ? 59  ILE E N     1 
ATOM   11388 C CA    . ILE F 2 77  ? 88.690  142.147 128.177 1.00 49.76  ? 59  ILE E CA    1 
ATOM   11389 C C     . ILE F 2 77  ? 88.960  141.757 126.729 1.00 49.76  ? 59  ILE E C     1 
ATOM   11390 O O     . ILE F 2 77  ? 89.862  142.303 126.083 1.00 49.76  ? 59  ILE E O     1 
ATOM   11391 C CB    . ILE F 2 77  ? 89.528  141.261 129.139 1.00 49.76  ? 59  ILE E CB    1 
ATOM   11392 C CG1   . ILE F 2 77  ? 89.000  139.825 129.285 1.00 49.76  ? 59  ILE E CG1   1 
ATOM   11393 C CG2   . ILE F 2 77  ? 89.611  141.901 130.534 1.00 49.76  ? 59  ILE E CG2   1 
ATOM   11394 C CD1   . ILE F 2 77  ? 89.786  138.933 130.262 1.00 49.76  ? 59  ILE E CD1   1 
ATOM   11395 N N     . ARG F 2 78  ? 88.188  140.803 126.199 1.00 52.27  ? 60  ARG E N     1 
ATOM   11396 C CA    . ARG F 2 78  ? 88.375  140.374 124.817 1.00 52.27  ? 60  ARG E CA    1 
ATOM   11397 C C     . ARG F 2 78  ? 88.046  141.485 123.824 1.00 52.27  ? 60  ARG E C     1 
ATOM   11398 O O     . ARG F 2 78  ? 88.618  141.520 122.729 1.00 52.27  ? 60  ARG E O     1 
ATOM   11399 C CB    . ARG F 2 78  ? 87.519  139.135 124.550 1.00 52.27  ? 60  ARG E CB    1 
ATOM   11400 C CG    . ARG F 2 78  ? 87.923  138.315 123.329 1.00 52.27  ? 60  ARG E CG    1 
ATOM   11401 C CD    . ARG F 2 78  ? 87.706  136.823 123.555 1.00 52.27  ? 60  ARG E CD    1 
ATOM   11402 N NE    . ARG F 2 78  ? 86.375  136.529 124.087 1.00 52.27  ? 60  ARG E NE    1 
ATOM   11403 C CZ    . ARG F 2 78  ? 86.055  135.518 124.891 1.00 52.27  ? 60  ARG E CZ    1 
ATOM   11404 N NH1   . ARG F 2 78  ? 86.933  134.590 125.246 1.00 52.27  ? 60  ARG E NH1   1 
ATOM   11405 N NH2   . ARG F 2 78  ? 84.807  135.424 125.341 1.00 52.27  ? 60  ARG E NH2   1 
ATOM   11406 N N     . GLU F 2 79  ? 87.141  142.398 124.183 1.00 51.11  ? 61  GLU E N     1 
ATOM   11407 C CA    . GLU F 2 79  ? 86.838  143.574 123.373 1.00 51.11  ? 61  GLU E CA    1 
ATOM   11408 C C     . GLU F 2 79  ? 87.771  144.754 123.641 1.00 51.11  ? 61  GLU E C     1 
ATOM   11409 O O     . GLU F 2 79  ? 87.621  145.795 122.993 1.00 51.11  ? 61  GLU E O     1 
ATOM   11410 C CB    . GLU F 2 79  ? 85.385  144.010 123.602 1.00 51.11  ? 61  GLU E CB    1 
ATOM   11411 C CG    . GLU F 2 79  ? 84.349  143.082 122.966 1.00 51.11  ? 61  GLU E CG    1 
ATOM   11412 C CD    . GLU F 2 79  ? 82.940  143.657 122.968 1.00 51.11  ? 61  GLU E CD    1 
ATOM   11413 O OE1   . GLU F 2 79  ? 82.758  144.829 123.362 1.00 51.11  ? 61  GLU E OE1   1 
ATOM   11414 O OE2   . GLU F 2 79  ? 82.007  142.930 122.569 1.00 51.11  ? 61  GLU E OE2   1 
ATOM   11415 N N     . GLY F 2 80  ? 88.731  144.627 124.554 1.00 52.43  ? 62  GLY E N     1 
ATOM   11416 C CA    . GLY F 2 80  ? 89.658  145.716 124.814 1.00 52.43  ? 62  GLY E CA    1 
ATOM   11417 C C     . GLY F 2 80  ? 89.026  146.942 125.435 1.00 52.43  ? 62  GLY E C     1 
ATOM   11418 O O     . GLY F 2 80  ? 89.312  148.065 125.000 1.00 52.43  ? 62  GLY E O     1 
ATOM   11419 N N     . LYS F 2 81  ? 88.170  146.750 126.444 1.00 50.76  ? 63  LYS E N     1 
ATOM   11420 C CA    . LYS F 2 81  ? 87.469  147.823 127.147 1.00 50.76  ? 63  LYS E CA    1 
ATOM   11421 C C     . LYS F 2 81  ? 87.797  147.869 128.636 1.00 50.76  ? 63  LYS E C     1 
ATOM   11422 O O     . LYS F 2 81  ? 87.065  148.513 129.397 1.00 50.76  ? 63  LYS E O     1 
ATOM   11423 C CB    . LYS F 2 81  ? 85.957  147.661 126.951 1.00 50.76  ? 63  LYS E CB    1 
ATOM   11424 C CG    . LYS F 2 81  ? 85.185  148.954 126.678 1.00 50.76  ? 63  LYS E CG    1 
ATOM   11425 C CD    . LYS F 2 81  ? 83.828  148.671 126.050 1.00 50.76  ? 63  LYS E CD    1 
ATOM   11426 C CE    . LYS F 2 81  ? 83.929  148.505 124.540 1.00 50.76  ? 63  LYS E CE    1 
ATOM   11427 N NZ    . LYS F 2 81  ? 82.642  148.059 123.938 1.00 50.76  ? 63  LYS E NZ    1 
ATOM   11428 N N     . ILE F 2 82  ? 88.887  147.220 129.068 1.00 49.00  ? 64  ILE E N     1 
ATOM   11429 C CA    . ILE F 2 82  ? 89.209  147.068 130.486 1.00 49.00  ? 64  ILE E CA    1 
ATOM   11430 C C     . ILE F 2 82  ? 90.234  148.091 130.973 1.00 49.00  ? 64  ILE E C     1 
ATOM   11431 O O     . ILE F 2 82  ? 90.701  147.988 132.115 1.00 49.00  ? 64  ILE E O     1 
ATOM   11432 C CB    . ILE F 2 82  ? 89.712  145.623 130.700 1.00 49.00  ? 64  ILE E CB    1 
ATOM   11433 C CG1   . ILE F 2 82  ? 89.524  145.126 132.145 1.00 49.00  ? 64  ILE E CG1   1 
ATOM   11434 C CG2   . ILE F 2 82  ? 91.185  145.471 130.269 1.00 49.00  ? 64  ILE E CG2   1 
ATOM   11435 C CD1   . ILE F 2 82  ? 88.104  144.728 132.479 1.00 49.00  ? 64  ILE E CD1   1 
ATOM   11436 N N     . ALA F 2 83  ? 90.616  149.062 130.141 1.00 48.57  ? 65  ALA E N     1 
ATOM   11437 C CA    . ALA F 2 83  ? 91.757  149.916 130.447 1.00 48.57  ? 65  ALA E CA    1 
ATOM   11438 C C     . ALA F 2 83  ? 91.442  150.812 131.639 1.00 48.57  ? 65  ALA E C     1 
ATOM   11439 O O     . ALA F 2 83  ? 90.474  151.579 131.611 1.00 48.57  ? 65  ALA E O     1 
ATOM   11440 C CB    . ALA F 2 83  ? 92.126  150.752 129.226 1.00 48.57  ? 65  ALA E CB    1 
ATOM   11441 N N     . GLY F 2 84  ? 92.255  150.698 132.687 1.00 46.40  ? 66  GLY E N     1 
ATOM   11442 C CA    . GLY F 2 84  ? 92.032  151.431 133.915 1.00 46.40  ? 66  GLY E CA    1 
ATOM   11443 C C     . GLY F 2 84  ? 91.089  150.771 134.893 1.00 46.40  ? 66  GLY E C     1 
ATOM   11444 O O     . GLY F 2 84  ? 90.465  151.481 135.691 1.00 46.40  ? 66  GLY E O     1 
ATOM   11445 N N     . ARG F 2 85  ? 90.953  149.443 134.851 1.00 45.54  ? 67  ARG E N     1 
ATOM   11446 C CA    . ARG F 2 85  ? 90.080  148.692 135.744 1.00 45.54  ? 67  ARG E CA    1 
ATOM   11447 C C     . ARG F 2 85  ? 90.791  147.445 136.250 1.00 45.54  ? 67  ARG E C     1 
ATOM   11448 O O     . ARG F 2 85  ? 91.860  147.062 135.771 1.00 45.54  ? 67  ARG E O     1 
ATOM   11449 C CB    . ARG F 2 85  ? 88.772  148.290 135.049 1.00 45.54  ? 67  ARG E CB    1 
ATOM   11450 C CG    . ARG F 2 85  ? 87.986  149.448 134.470 1.00 45.54  ? 67  ARG E CG    1 
ATOM   11451 C CD    . ARG F 2 85  ? 86.627  148.979 133.986 1.00 45.54  ? 67  ARG E CD    1 
ATOM   11452 N NE    . ARG F 2 85  ? 85.915  150.016 133.244 1.00 45.54  ? 67  ARG E NE    1 
ATOM   11453 C CZ    . ARG F 2 85  ? 84.609  150.036 133.001 1.00 45.54  ? 67  ARG E CZ    1 
ATOM   11454 N NH1   . ARG F 2 85  ? 83.799  149.070 133.417 1.00 45.54  ? 67  ARG E NH1   1 
ATOM   11455 N NH2   . ARG F 2 85  ? 84.096  151.052 132.315 1.00 45.54  ? 67  ARG E NH2   1 
ATOM   11456 N N     . ALA F 2 86  ? 90.166  146.821 137.245 1.00 44.94  ? 68  ALA E N     1 
ATOM   11457 C CA    . ALA F 2 86  ? 90.592  145.542 137.790 1.00 44.94  ? 68  ALA E CA    1 
ATOM   11458 C C     . ALA F 2 86  ? 89.335  144.812 138.241 1.00 44.94  ? 68  ALA E C     1 
ATOM   11459 O O     . ALA F 2 86  ? 88.231  145.359 138.173 1.00 44.94  ? 68  ALA E O     1 
ATOM   11460 C CB    . ALA F 2 86  ? 91.595  145.734 138.931 1.00 44.94  ? 68  ALA E CB    1 
ATOM   11461 N N     . ILE F 2 87  ? 89.504  143.571 138.705 1.00 46.66  ? 69  ILE E N     1 
ATOM   11462 C CA    . ILE F 2 87  ? 88.396  142.709 139.112 1.00 46.66  ? 69  ILE E CA    1 
ATOM   11463 C C     . ILE F 2 87  ? 88.602  142.301 140.561 1.00 46.66  ? 69  ILE E C     1 
ATOM   11464 O O     . ILE F 2 87  ? 89.731  142.029 140.978 1.00 46.66  ? 69  ILE E O     1 
ATOM   11465 C CB    . ILE F 2 87  ? 88.285  141.471 138.196 1.00 46.66  ? 69  ILE E CB    1 
ATOM   11466 C CG1   . ILE F 2 87  ? 88.107  141.931 136.742 1.00 46.66  ? 69  ILE E CG1   1 
ATOM   11467 C CG2   . ILE F 2 87  ? 87.150  140.533 138.667 1.00 46.66  ? 69  ILE E CG2   1 
ATOM   11468 C CD1   . ILE F 2 87  ? 89.347  141.761 135.901 1.00 46.66  ? 69  ILE E CD1   1 
ATOM   11469 N N     . LEU F 2 88  ? 87.506  142.264 141.324 1.00 47.54  ? 70  LEU E N     1 
ATOM   11470 C CA    . LEU F 2 88  ? 87.503  141.858 142.725 1.00 47.54  ? 70  LEU E CA    1 
ATOM   11471 C C     . LEU F 2 88  ? 86.497  140.731 142.900 1.00 47.54  ? 70  LEU E C     1 
ATOM   11472 O O     . LEU F 2 88  ? 85.358  140.839 142.436 1.00 47.54  ? 70  LEU E O     1 
ATOM   11473 C CB    . LEU F 2 88  ? 87.157  143.042 143.643 1.00 47.54  ? 70  LEU E CB    1 
ATOM   11474 C CG    . LEU F 2 88  ? 86.836  142.807 145.127 1.00 47.54  ? 70  LEU E CG    1 
ATOM   11475 C CD1   . LEU F 2 88  ? 87.932  142.043 145.856 1.00 47.54  ? 70  LEU E CD1   1 
ATOM   11476 C CD2   . LEU F 2 88  ? 86.597  144.134 145.824 1.00 47.54  ? 70  LEU E CD2   1 
ATOM   11477 N N     . ILE F 2 89  ? 86.927  139.655 143.555 1.00 49.91  ? 71  ILE E N     1 
ATOM   11478 C CA    . ILE F 2 89  ? 86.086  138.504 143.882 1.00 49.91  ? 71  ILE E CA    1 
ATOM   11479 C C     . ILE F 2 89  ? 85.960  138.500 145.400 1.00 49.91  ? 71  ILE E C     1 
ATOM   11480 O O     . ILE F 2 89  ? 86.905  138.125 146.104 1.00 49.91  ? 71  ILE E O     1 
ATOM   11481 C CB    . ILE F 2 89  ? 86.676  137.181 143.356 1.00 49.91  ? 71  ILE E CB    1 
ATOM   11482 C CG1   . ILE F 2 89  ? 87.124  137.299 141.888 1.00 49.91  ? 71  ILE E CG1   1 
ATOM   11483 C CG2   . ILE F 2 89  ? 85.654  136.035 143.450 1.00 49.91  ? 71  ILE E CG2   1 
ATOM   11484 C CD1   . ILE F 2 89  ? 87.681  136.016 141.315 1.00 49.91  ? 71  ILE E CD1   1 
ATOM   11485 N N     . ALA F 2 90  ? 84.782  138.878 145.902 1.00 51.14  ? 72  ALA E N     1 
ATOM   11486 C CA    . ALA F 2 90  ? 84.594  139.230 147.307 1.00 51.14  ? 72  ALA E CA    1 
ATOM   11487 C C     . ALA F 2 90  ? 83.519  138.379 147.966 1.00 51.14  ? 72  ALA E C     1 
ATOM   11488 O O     . ALA F 2 90  ? 82.621  138.913 148.623 1.00 51.14  ? 72  ALA E O     1 
ATOM   11489 C CB    . ALA F 2 90  ? 84.232  140.710 147.434 1.00 51.14  ? 72  ALA E CB    1 
ATOM   11490 N N     . GLY F 2 91  ? 83.597  137.060 147.778 1.00 54.05  ? 73  GLY E N     1 
ATOM   11491 C CA    . GLY F 2 91  ? 82.718  136.122 148.439 1.00 54.05  ? 73  GLY E CA    1 
ATOM   11492 C C     . GLY F 2 91  ? 83.355  135.488 149.665 1.00 54.05  ? 73  GLY E C     1 
ATOM   11493 O O     . GLY F 2 91  ? 84.434  135.871 150.120 1.00 54.05  ? 73  GLY E O     1 
ATOM   11494 N N     . GLN F 2 92  ? 82.671  134.480 150.185 1.00 57.44  ? 74  GLN E N     1 
ATOM   11495 C CA    . GLN F 2 92  ? 83.124  133.758 151.361 1.00 57.44  ? 74  GLN E CA    1 
ATOM   11496 C C     . GLN F 2 92  ? 84.285  132.834 150.993 1.00 57.44  ? 74  GLN E C     1 
ATOM   11497 O O     . GLN F 2 92  ? 84.434  132.453 149.830 1.00 57.44  ? 74  GLN E O     1 
ATOM   11498 C CB    . GLN F 2 92  ? 81.959  132.964 151.953 1.00 57.44  ? 74  GLN E CB    1 
ATOM   11499 C CG    . GLN F 2 92  ? 80.957  133.808 152.739 1.00 57.44  ? 74  GLN E CG    1 
ATOM   11500 C CD    . GLN F 2 92  ? 80.011  134.593 151.845 1.00 57.44  ? 74  GLN E CD    1 
ATOM   11501 O OE1   . GLN F 2 92  ? 79.426  134.046 150.910 1.00 57.44  ? 74  GLN E OE1   1 
ATOM   11502 N NE2   . GLN F 2 92  ? 79.863  135.883 152.123 1.00 57.44  ? 74  GLN E NE2   1 
ATOM   11503 N N     . PRO F 2 93  ? 85.133  132.458 151.955 1.00 55.46  ? 75  PRO E N     1 
ATOM   11504 C CA    . PRO F 2 93  ? 86.310  131.658 151.602 1.00 55.46  ? 75  PRO E CA    1 
ATOM   11505 C C     . PRO F 2 93  ? 85.935  130.223 151.274 1.00 55.46  ? 75  PRO E C     1 
ATOM   11506 O O     . PRO F 2 93  ? 84.917  129.693 151.724 1.00 55.46  ? 75  PRO E O     1 
ATOM   11507 C CB    . PRO F 2 93  ? 87.191  131.733 152.852 1.00 55.46  ? 75  PRO E CB    1 
ATOM   11508 C CG    . PRO F 2 93  ? 86.278  132.075 153.971 1.00 55.46  ? 75  PRO E CG    1 
ATOM   11509 C CD    . PRO F 2 93  ? 84.959  132.534 153.419 1.00 55.46  ? 75  PRO E CD    1 
ATOM   11510 N N     . GLY F 2 94  ? 86.792  129.590 150.477 1.00 57.52  ? 76  GLY E N     1 
ATOM   11511 C CA    . GLY F 2 94  ? 86.542  128.237 150.022 1.00 57.52  ? 76  GLY E CA    1 
ATOM   11512 C C     . GLY F 2 94  ? 85.305  128.143 149.153 1.00 57.52  ? 76  GLY E C     1 
ATOM   11513 O O     . GLY F 2 94  ? 84.481  127.242 149.338 1.00 57.52  ? 76  GLY E O     1 
ATOM   11514 N N     . THR F 2 95  ? 85.170  129.078 148.210 1.00 54.13  ? 77  THR E N     1 
ATOM   11515 C CA    . THR F 2 95  ? 84.017  129.176 147.317 1.00 54.13  ? 77  THR E CA    1 
ATOM   11516 C C     . THR F 2 95  ? 84.484  129.428 145.887 1.00 54.13  ? 77  THR E C     1 
ATOM   11517 O O     . THR F 2 95  ? 83.890  130.217 145.146 1.00 54.13  ? 77  THR E O     1 
ATOM   11518 C CB    . THR F 2 95  ? 83.060  130.277 147.783 1.00 54.13  ? 77  THR E CB    1 
ATOM   11519 O OG1   . THR F 2 95  ? 82.961  130.247 149.212 1.00 54.13  ? 77  THR E OG1   1 
ATOM   11520 C CG2   . THR F 2 95  ? 81.654  130.092 147.201 1.00 54.13  ? 77  THR E CG2   1 
ATOM   11521 N N     . GLY F 2 96  ? 85.564  128.766 145.485 1.00 53.86  ? 78  GLY E N     1 
ATOM   11522 C CA    . GLY F 2 96  ? 86.004  128.797 144.101 1.00 53.86  ? 78  GLY E CA    1 
ATOM   11523 C C     . GLY F 2 96  ? 86.486  130.137 143.587 1.00 53.86  ? 78  GLY E C     1 
ATOM   11524 O O     . GLY F 2 96  ? 86.254  130.460 142.416 1.00 53.86  ? 78  GLY E O     1 
ATOM   11525 N N     . LYS F 2 97  ? 87.148  130.931 144.431 1.00 52.22  ? 79  LYS E N     1 
ATOM   11526 C CA    . LYS F 2 97  ? 87.791  132.150 143.948 1.00 52.22  ? 79  LYS E CA    1 
ATOM   11527 C C     . LYS F 2 97  ? 88.895  131.819 142.954 1.00 52.22  ? 79  LYS E C     1 
ATOM   11528 O O     . LYS F 2 97  ? 88.924  132.335 141.826 1.00 52.22  ? 79  LYS E O     1 
ATOM   11529 C CB    . LYS F 2 97  ? 88.377  132.927 145.123 1.00 52.22  ? 79  LYS E CB    1 
ATOM   11530 C CG    . LYS F 2 97  ? 87.365  133.549 146.060 1.00 52.22  ? 79  LYS E CG    1 
ATOM   11531 C CD    . LYS F 2 97  ? 87.992  133.832 147.422 1.00 52.22  ? 79  LYS E CD    1 
ATOM   11532 C CE    . LYS F 2 97  ? 87.497  135.132 148.003 1.00 52.22  ? 79  LYS E CE    1 
ATOM   11533 N NZ    . LYS F 2 97  ? 86.026  135.180 148.063 1.00 52.22  ? 79  LYS E NZ    1 
ATOM   11534 N N     . THR F 2 98  ? 89.812  130.940 143.362 1.00 54.01  ? 80  THR E N     1 
ATOM   11535 C CA    . THR F 2 98  ? 90.908  130.542 142.491 1.00 54.01  ? 80  THR E CA    1 
ATOM   11536 C C     . THR F 2 98  ? 90.397  129.801 141.268 1.00 54.01  ? 80  THR E C     1 
ATOM   11537 O O     . THR F 2 98  ? 90.971  129.937 140.185 1.00 54.01  ? 80  THR E O     1 
ATOM   11538 C CB    . THR F 2 98  ? 91.898  129.671 143.263 1.00 54.01  ? 80  THR E CB    1 
ATOM   11539 O OG1   . THR F 2 98  ? 91.185  128.839 144.186 1.00 54.01  ? 80  THR E OG1   1 
ATOM   11540 C CG2   . THR F 2 98  ? 92.889  130.536 144.026 1.00 54.01  ? 80  THR E CG2   1 
ATOM   11541 N N     . ALA F 2 99  ? 89.323  129.020 141.422 1.00 52.46  ? 81  ALA E N     1 
ATOM   11542 C CA    . ALA F 2 99  ? 88.743  128.315 140.284 1.00 52.46  ? 81  ALA E CA    1 
ATOM   11543 C C     . ALA F 2 99  ? 88.233  129.291 139.233 1.00 52.46  ? 81  ALA E C     1 
ATOM   11544 O O     . ALA F 2 99  ? 88.463  129.098 138.035 1.00 52.46  ? 81  ALA E O     1 
ATOM   11545 C CB    . ALA F 2 99  ? 87.614  127.399 140.755 1.00 52.46  ? 81  ALA E CB    1 
ATOM   11546 N N     . ILE F 2 100 ? 87.559  130.361 139.666 1.00 49.64  ? 82  ILE E N     1 
ATOM   11547 C CA    . ILE F 2 100 ? 87.121  131.393 138.730 1.00 49.64  ? 82  ILE E CA    1 
ATOM   11548 C C     . ILE F 2 100 ? 88.326  132.096 138.115 1.00 49.64  ? 82  ILE E C     1 
ATOM   11549 O O     . ILE F 2 100 ? 88.284  132.490 136.943 1.00 49.64  ? 82  ILE E O     1 
ATOM   11550 C CB    . ILE F 2 100 ? 86.159  132.381 139.430 1.00 49.64  ? 82  ILE E CB    1 
ATOM   11551 C CG1   . ILE F 2 100 ? 84.836  131.663 139.768 1.00 49.64  ? 82  ILE E CG1   1 
ATOM   11552 C CG2   . ILE F 2 100 ? 85.935  133.647 138.540 1.00 49.64  ? 82  ILE E CG2   1 
ATOM   11553 C CD1   . ILE F 2 100 ? 83.829  132.462 140.594 1.00 49.64  ? 82  ILE E CD1   1 
ATOM   11554 N N     . ALA F 2 101 ? 89.410  132.265 138.879 1.00 53.63  ? 83  ALA E N     1 
ATOM   11555 C CA    . ALA F 2 101 ? 90.608  132.901 138.330 1.00 53.63  ? 83  ALA E CA    1 
ATOM   11556 C C     . ALA F 2 101 ? 91.217  132.073 137.199 1.00 53.63  ? 83  ALA E C     1 
ATOM   11557 O O     . ALA F 2 101 ? 91.486  132.592 136.104 1.00 53.63  ? 83  ALA E O     1 
ATOM   11558 C CB    . ALA F 2 101 ? 91.632  133.121 139.441 1.00 53.63  ? 83  ALA E CB    1 
ATOM   11559 N N     . MET F 2 102 ? 91.439  130.775 137.443 1.00 54.44  ? 84  MET E N     1 
ATOM   11560 C CA    . MET F 2 102 ? 91.978  129.930 136.378 1.00 54.44  ? 84  MET E CA    1 
ATOM   11561 C C     . MET F 2 102 ? 90.984  129.775 135.237 1.00 54.44  ? 84  MET E C     1 
ATOM   11562 O O     . MET F 2 102 ? 91.400  129.631 134.086 1.00 54.44  ? 84  MET E O     1 
ATOM   11563 C CB    . MET F 2 102 ? 92.396  128.536 136.870 1.00 54.44  ? 84  MET E CB    1 
ATOM   11564 C CG    . MET F 2 102 ? 93.091  128.446 138.216 1.00 54.44  ? 84  MET E CG    1 
ATOM   11565 S SD    . MET F 2 102 ? 94.013  126.914 138.431 1.00 54.44  ? 84  MET E SD    1 
ATOM   11566 C CE    . MET F 2 102 ? 94.055  126.806 140.219 1.00 54.44  ? 84  MET E CE    1 
ATOM   11567 N N     . GLY F 2 103 ? 89.680  129.810 135.523 1.00 53.17  ? 85  GLY E N     1 
ATOM   11568 C CA    . GLY F 2 103 ? 88.701  129.777 134.451 1.00 53.17  ? 85  GLY E CA    1 
ATOM   11569 C C     . GLY F 2 103 ? 88.792  130.989 133.547 1.00 53.17  ? 85  GLY E C     1 
ATOM   11570 O O     . GLY F 2 103 ? 88.699  130.870 132.324 1.00 53.17  ? 85  GLY E O     1 
ATOM   11571 N N     . MET F 2 104 ? 88.986  132.171 134.139 1.00 51.60  ? 86  MET E N     1 
ATOM   11572 C CA    . MET F 2 104 ? 89.194  133.383 133.347 1.00 51.60  ? 86  MET E CA    1 
ATOM   11573 C C     . MET F 2 104 ? 90.455  133.266 132.498 1.00 51.60  ? 86  MET E C     1 
ATOM   11574 O O     . MET F 2 104 ? 90.445  133.567 131.293 1.00 51.60  ? 86  MET E O     1 
ATOM   11575 C CB    . MET F 2 104 ? 89.296  134.604 134.264 1.00 51.60  ? 86  MET E CB    1 
ATOM   11576 C CG    . MET F 2 104 ? 88.011  135.385 134.437 1.00 51.60  ? 86  MET E CG    1 
ATOM   11577 S SD    . MET F 2 104 ? 88.295  136.916 135.347 1.00 51.60  ? 86  MET E SD    1 
ATOM   11578 C CE    . MET F 2 104 ? 86.778  137.049 136.286 1.00 51.60  ? 86  MET E CE    1 
ATOM   11579 N N     . ALA F 2 105 ? 91.549  132.807 133.117 1.00 55.50  ? 87  ALA E N     1 
ATOM   11580 C CA    . ALA F 2 105 ? 92.822  132.704 132.407 1.00 55.50  ? 87  ALA E CA    1 
ATOM   11581 C C     . ALA F 2 105 ? 92.748  131.692 131.269 1.00 55.50  ? 87  ALA E C     1 
ATOM   11582 O O     . ALA F 2 105 ? 93.357  131.891 130.212 1.00 55.50  ? 87  ALA E O     1 
ATOM   11583 C CB    . ALA F 2 105 ? 93.934  132.328 133.384 1.00 55.50  ? 87  ALA E CB    1 
ATOM   11584 N N     . LYS F 2 106 ? 92.000  130.603 131.464 1.00 56.88  ? 88  LYS E N     1 
ATOM   11585 C CA    . LYS F 2 106 ? 91.861  129.599 130.414 1.00 56.88  ? 88  LYS E CA    1 
ATOM   11586 C C     . LYS F 2 106 ? 90.935  130.090 129.310 1.00 56.88  ? 88  LYS E C     1 
ATOM   11587 O O     . LYS F 2 106 ? 91.195  129.854 128.125 1.00 56.88  ? 88  LYS E O     1 
ATOM   11588 C CB    . LYS F 2 106 ? 91.331  128.284 130.994 1.00 56.88  ? 88  LYS E CB    1 
ATOM   11589 C CG    . LYS F 2 106 ? 92.037  127.025 130.491 1.00 56.88  ? 88  LYS E CG    1 
ATOM   11590 C CD    . LYS F 2 106 ? 93.472  126.848 131.025 1.00 56.88  ? 88  LYS E CD    1 
ATOM   11591 C CE    . LYS F 2 106 ? 93.524  126.453 132.504 1.00 56.88  ? 88  LYS E CE    1 
ATOM   11592 N NZ    . LYS F 2 106 ? 94.919  126.435 133.027 1.00 56.88  ? 88  LYS E NZ    1 
ATOM   11593 N N     . SER F 2 107 ? 89.848  130.775 129.676 1.00 52.51  ? 89  SER E N     1 
ATOM   11594 C CA    . SER F 2 107 ? 88.890  131.217 128.673 1.00 52.51  ? 89  SER E CA    1 
ATOM   11595 C C     . SER F 2 107 ? 89.466  132.315 127.790 1.00 52.51  ? 89  SER E C     1 
ATOM   11596 O O     . SER F 2 107 ? 89.071  132.433 126.626 1.00 52.51  ? 89  SER E O     1 
ATOM   11597 C CB    . SER F 2 107 ? 87.606  131.690 129.351 1.00 52.51  ? 89  SER E CB    1 
ATOM   11598 O OG    . SER F 2 107 ? 86.606  131.987 128.394 1.00 52.51  ? 89  SER E OG    1 
ATOM   11599 N N     . LEU F 2 108 ? 90.390  133.128 128.315 1.00 55.84  ? 90  LEU E N     1 
ATOM   11600 C CA    . LEU F 2 108 ? 91.165  133.991 127.423 1.00 55.84  ? 90  LEU E CA    1 
ATOM   11601 C C     . LEU F 2 108 ? 91.996  133.177 126.443 1.00 55.84  ? 90  LEU E C     1 
ATOM   11602 O O     . LEU F 2 108 ? 92.037  133.491 125.247 1.00 55.84  ? 90  LEU E O     1 
ATOM   11603 C CB    . LEU F 2 108 ? 92.075  134.936 128.223 1.00 55.84  ? 90  LEU E CB    1 
ATOM   11604 C CG    . LEU F 2 108 ? 91.678  136.341 128.709 1.00 55.84  ? 90  LEU E CG    1 
ATOM   11605 C CD1   . LEU F 2 108 ? 92.940  137.162 128.859 1.00 55.84  ? 90  LEU E CD1   1 
ATOM   11606 C CD2   . LEU F 2 108 ? 90.761  137.080 127.734 1.00 55.84  ? 90  LEU E CD2   1 
ATOM   11607 N N     . GLY F 2 109 ? 92.654  132.126 126.922 1.00 62.85  ? 91  GLY E N     1 
ATOM   11608 C CA    . GLY F 2 109 ? 93.489  131.307 126.066 1.00 62.85  ? 91  GLY E CA    1 
ATOM   11609 C C     . GLY F 2 109 ? 94.533  130.523 126.830 1.00 62.85  ? 91  GLY E C     1 
ATOM   11610 O O     . GLY F 2 109 ? 94.995  130.952 127.891 1.00 62.85  ? 91  GLY E O     1 
ATOM   11611 N N     . LEU F 2 110 ? 94.906  129.361 126.294 1.00 64.14  ? 92  LEU E N     1 
ATOM   11612 C CA    . LEU F 2 110 ? 95.946  128.555 126.922 1.00 64.14  ? 92  LEU E CA    1 
ATOM   11613 C C     . LEU F 2 110 ? 97.299  129.254 126.866 1.00 64.14  ? 92  LEU E C     1 
ATOM   11614 O O     . LEU F 2 110 ? 98.130  129.066 127.761 1.00 64.14  ? 92  LEU E O     1 
ATOM   11615 C CB    . LEU F 2 110 ? 96.020  127.184 126.245 1.00 64.14  ? 92  LEU E CB    1 
ATOM   11616 C CG    . LEU F 2 110 ? 94.724  126.362 126.198 1.00 64.14  ? 92  LEU E CG    1 
ATOM   11617 C CD1   . LEU F 2 110 ? 94.944  125.088 125.402 1.00 64.14  ? 92  LEU E CD1   1 
ATOM   11618 C CD2   . LEU F 2 110 ? 94.202  126.039 127.591 1.00 64.14  ? 92  LEU E CD2   1 
ATOM   11619 N N     . GLU F 2 111 ? 97.537  130.061 125.829 1.00 72.37  ? 93  GLU E N     1 
ATOM   11620 C CA    . GLU F 2 111 ? 98.796  130.788 125.716 1.00 72.37  ? 93  GLU E CA    1 
ATOM   11621 C C     . GLU F 2 111 ? 98.965  131.862 126.788 1.00 72.37  ? 93  GLU E C     1 
ATOM   11622 O O     . GLU F 2 111 ? 100.104 132.223 127.103 1.00 72.37  ? 93  GLU E O     1 
ATOM   11623 C CB    . GLU F 2 111 ? 98.920  131.420 124.320 1.00 72.37  ? 93  GLU E CB    1 
ATOM   11624 C CG    . GLU F 2 111 ? 97.818  132.422 123.914 1.00 72.37  ? 93  GLU E CG    1 
ATOM   11625 C CD    . GLU F 2 111 ? 96.733  131.791 123.065 1.00 72.37  ? 93  GLU E CD    1 
ATOM   11626 O OE1   . GLU F 2 111 ? 96.228  130.715 123.448 1.00 72.37  ? 93  GLU E OE1   1 
ATOM   11627 O OE2   . GLU F 2 111 ? 96.384  132.374 122.018 1.00 72.37  ? 93  GLU E OE2   1 
ATOM   11628 N N     . THR F 2 112 ? 97.876  132.376 127.355 1.00 65.40  ? 94  THR E N     1 
ATOM   11629 C CA    . THR F 2 112 ? 97.975  133.527 128.250 1.00 65.40  ? 94  THR E CA    1 
ATOM   11630 C C     . THR F 2 112 ? 98.475  133.063 129.618 1.00 65.40  ? 94  THR E C     1 
ATOM   11631 O O     . THR F 2 112 ? 97.857  132.172 130.212 1.00 65.40  ? 94  THR E O     1 
ATOM   11632 C CB    . THR F 2 112 ? 96.628  134.233 128.413 1.00 65.40  ? 94  THR E CB    1 
ATOM   11633 O OG1   . THR F 2 112 ? 95.821  133.523 129.361 1.00 65.40  ? 94  THR E OG1   1 
ATOM   11634 C CG2   . THR F 2 112 ? 95.885  134.371 127.080 1.00 65.40  ? 94  THR E CG2   1 
ATOM   11635 N N     . PRO F 2 113 ? 99.565  133.618 130.162 1.00 65.18  ? 95  PRO E N     1 
ATOM   11636 C CA    . PRO F 2 113 ? 100.053 133.111 131.448 1.00 65.18  ? 95  PRO E CA    1 
ATOM   11637 C C     . PRO F 2 113 ? 99.151  133.532 132.596 1.00 65.18  ? 95  PRO E C     1 
ATOM   11638 O O     . PRO F 2 113 ? 98.380  134.489 132.500 1.00 65.18  ? 95  PRO E O     1 
ATOM   11639 C CB    . PRO F 2 113 ? 101.442 133.739 131.577 1.00 65.18  ? 95  PRO E CB    1 
ATOM   11640 C CG    . PRO F 2 113 ? 101.327 135.001 130.858 1.00 65.18  ? 95  PRO E CG    1 
ATOM   11641 C CD    . PRO F 2 113 ? 100.397 134.756 129.712 1.00 65.18  ? 95  PRO E CD    1 
ATOM   11642 N N     . PHE F 2 114 ? 99.259  132.781 133.693 1.00 58.23  ? 96  PHE E N     1 
ATOM   11643 C CA    . PHE F 2 114 ? 98.518  133.029 134.925 1.00 58.23  ? 96  PHE E CA    1 
ATOM   11644 C C     . PHE F 2 114 ? 99.517  133.125 136.067 1.00 58.23  ? 96  PHE E C     1 
ATOM   11645 O O     . PHE F 2 114 ? 100.258 132.170 136.321 1.00 58.23  ? 96  PHE E O     1 
ATOM   11646 C CB    . PHE F 2 114 ? 97.503  131.913 135.186 1.00 58.23  ? 96  PHE E CB    1 
ATOM   11647 C CG    . PHE F 2 114 ? 96.731  132.079 136.461 1.00 58.23  ? 96  PHE E CG    1 
ATOM   11648 C CD1   . PHE F 2 114 ? 95.666  132.959 136.531 1.00 58.23  ? 96  PHE E CD1   1 
ATOM   11649 C CD2   . PHE F 2 114 ? 97.065  131.350 137.589 1.00 58.23  ? 96  PHE E CD2   1 
ATOM   11650 C CE1   . PHE F 2 114 ? 94.953  133.112 137.702 1.00 58.23  ? 96  PHE E CE1   1 
ATOM   11651 C CE2   . PHE F 2 114 ? 96.356  131.500 138.762 1.00 58.23  ? 96  PHE E CE2   1 
ATOM   11652 C CZ    . PHE F 2 114 ? 95.298  132.381 138.819 1.00 58.23  ? 96  PHE E CZ    1 
ATOM   11653 N N     . ALA F 2 115 ? 99.529  134.271 136.755 1.00 60.03  ? 97  ALA E N     1 
ATOM   11654 C CA    . ALA F 2 115 ? 100.451 134.547 137.857 1.00 60.03  ? 97  ALA E CA    1 
ATOM   11655 C C     . ALA F 2 115 ? 99.672  134.482 139.166 1.00 60.03  ? 97  ALA E C     1 
ATOM   11656 O O     . ALA F 2 115 ? 98.958  135.424 139.523 1.00 60.03  ? 97  ALA E O     1 
ATOM   11657 C CB    . ALA F 2 115 ? 101.119 135.905 137.681 1.00 60.03  ? 97  ALA E CB    1 
ATOM   11658 N N     . MET F 2 116 ? 99.820  133.368 139.876 1.00 59.24  ? 98  MET E N     1 
ATOM   11659 C CA    . MET F 2 116 ? 99.206  133.194 141.183 1.00 59.24  ? 98  MET E CA    1 
ATOM   11660 C C     . MET F 2 116 ? 100.083 133.851 142.240 1.00 59.24  ? 98  MET E C     1 
ATOM   11661 O O     . MET F 2 116 ? 101.314 133.781 142.176 1.00 59.24  ? 98  MET E O     1 
ATOM   11662 C CB    . MET F 2 116 ? 99.025  131.697 141.472 1.00 59.24  ? 98  MET E CB    1 
ATOM   11663 C CG    . MET F 2 116 ? 98.484  131.289 142.857 1.00 59.24  ? 98  MET E CG    1 
ATOM   11664 S SD    . MET F 2 116 ? 96.730  131.631 143.058 1.00 59.24  ? 98  MET E SD    1 
ATOM   11665 C CE    . MET F 2 116 ? 96.634  131.839 144.834 1.00 59.24  ? 98  MET E CE    1 
ATOM   11666 N N     . ILE F 2 117 ? 99.446  134.494 143.218 1.00 61.27  ? 99  ILE E N     1 
ATOM   11667 C CA    . ILE F 2 117 ? 100.152 134.961 144.404 1.00 61.27  ? 99  ILE E CA    1 
ATOM   11668 C C     . ILE F 2 117 ? 99.110  135.168 145.491 1.00 61.27  ? 99  ILE E C     1 
ATOM   11669 O O     . ILE F 2 117 ? 97.938  135.420 145.201 1.00 61.27  ? 99  ILE E O     1 
ATOM   11670 C CB    . ILE F 2 117 ? 100.981 136.242 144.099 1.00 61.27  ? 99  ILE E CB    1 
ATOM   11671 C CG1   . ILE F 2 117 ? 101.775 136.747 145.320 1.00 61.27  ? 99  ILE E CG1   1 
ATOM   11672 C CG2   . ILE F 2 117 ? 100.111 137.378 143.534 1.00 61.27  ? 99  ILE E CG2   1 
ATOM   11673 C CD1   . ILE F 2 117 ? 102.823 135.780 145.841 1.00 61.27  ? 99  ILE E CD1   1 
ATOM   11674 N N     . ALA F 2 118 ? 99.530  135.005 146.745 1.00 62.54  ? 100 ALA E N     1 
ATOM   11675 C CA    . ALA F 2 118 ? 98.724  135.307 147.918 1.00 62.54  ? 100 ALA E CA    1 
ATOM   11676 C C     . ALA F 2 118 ? 99.368  136.453 148.686 1.00 62.54  ? 100 ALA E C     1 
ATOM   11677 O O     . ALA F 2 118 ? 100.579 136.673 148.606 1.00 62.54  ? 100 ALA E O     1 
ATOM   11678 C CB    . ALA F 2 118 ? 98.561  134.078 148.818 1.00 62.54  ? 100 ALA E CB    1 
ATOM   11679 N N     . GLY F 2 119 ? 98.532  137.188 149.420 1.00 63.95  ? 101 GLY E N     1 
ATOM   11680 C CA    . GLY F 2 119 ? 98.983  138.410 150.065 1.00 63.95  ? 101 GLY E CA    1 
ATOM   11681 C C     . GLY F 2 119 ? 100.032 138.192 151.136 1.00 63.95  ? 101 GLY E C     1 
ATOM   11682 O O     . GLY F 2 119 ? 100.905 139.040 151.334 1.00 63.95  ? 101 GLY E O     1 
ATOM   11683 N N     . SER F 2 120 ? 99.961  137.069 151.849 1.00 64.85  ? 102 SER E N     1 
ATOM   11684 C CA    . SER F 2 120 ? 100.918 136.800 152.916 1.00 64.85  ? 102 SER E CA    1 
ATOM   11685 C C     . SER F 2 120 ? 102.287 136.362 152.405 1.00 64.85  ? 102 SER E C     1 
ATOM   11686 O O     . SER F 2 120 ? 103.258 136.419 153.166 1.00 64.85  ? 102 SER E O     1 
ATOM   11687 C CB    . SER F 2 120 ? 100.365 135.726 153.851 1.00 64.85  ? 102 SER E CB    1 
ATOM   11688 O OG    . SER F 2 120 ? 100.078 134.537 153.139 1.00 64.85  ? 102 SER E OG    1 
ATOM   11689 N N     . GLU F 2 121 ? 102.395 135.935 151.143 1.00 66.42  ? 103 GLU E N     1 
ATOM   11690 C CA    . GLU F 2 121 ? 103.644 135.353 150.660 1.00 66.42  ? 103 GLU E CA    1 
ATOM   11691 C C     . GLU F 2 121 ? 104.707 136.405 150.376 1.00 66.42  ? 103 GLU E C     1 
ATOM   11692 O O     . GLU F 2 121 ? 105.900 136.120 150.524 1.00 66.42  ? 103 GLU E O     1 
ATOM   11693 C CB    . GLU F 2 121 ? 103.400 134.531 149.391 1.00 66.42  ? 103 GLU E CB    1 
ATOM   11694 C CG    . GLU F 2 121 ? 102.193 133.600 149.436 1.00 66.42  ? 103 GLU E CG    1 
ATOM   11695 C CD    . GLU F 2 121 ? 102.154 132.725 150.673 1.00 66.42  ? 103 GLU E CD    1 
ATOM   11696 O OE1   . GLU F 2 121 ? 101.722 133.218 151.735 1.00 66.42  ? 103 GLU E OE1   1 
ATOM   11697 O OE2   . GLU F 2 121 ? 102.546 131.544 150.585 1.00 66.42  ? 103 GLU E OE2   1 
ATOM   11698 N N     . ILE F 2 122 ? 104.302 137.607 149.955 1.00 70.19  ? 104 ILE E N     1 
ATOM   11699 C CA    . ILE F 2 122 ? 105.275 138.624 149.555 1.00 70.19  ? 104 ILE E CA    1 
ATOM   11700 C C     . ILE F 2 122 ? 106.120 139.096 150.738 1.00 70.19  ? 104 ILE E C     1 
ATOM   11701 O O     . ILE F 2 122 ? 107.272 139.508 150.554 1.00 70.19  ? 104 ILE E O     1 
ATOM   11702 C CB    . ILE F 2 122 ? 104.566 139.804 148.850 1.00 70.19  ? 104 ILE E CB    1 
ATOM   11703 C CG1   . ILE F 2 122 ? 103.511 140.491 149.741 1.00 70.19  ? 104 ILE E CG1   1 
ATOM   11704 C CG2   . ILE F 2 122 ? 103.910 139.323 147.553 1.00 70.19  ? 104 ILE E CG2   1 
ATOM   11705 C CD1   . ILE F 2 122 ? 103.018 141.806 149.185 1.00 70.19  ? 104 ILE E CD1   1 
ATOM   11706 N N     . PHE F 2 123 ? 105.581 139.043 151.958 1.00 69.14  ? 105 PHE E N     1 
ATOM   11707 C CA    . PHE F 2 123 ? 106.269 139.550 153.140 1.00 69.14  ? 105 PHE E CA    1 
ATOM   11708 C C     . PHE F 2 123 ? 107.264 138.559 153.744 1.00 69.14  ? 105 PHE E C     1 
ATOM   11709 O O     . PHE F 2 123 ? 107.709 138.779 154.876 1.00 69.14  ? 105 PHE E O     1 
ATOM   11710 C CB    . PHE F 2 123 ? 105.242 139.955 154.202 1.00 69.14  ? 105 PHE E CB    1 
ATOM   11711 C CG    . PHE F 2 123 ? 104.221 140.939 153.711 1.00 69.14  ? 105 PHE E CG    1 
ATOM   11712 C CD1   . PHE F 2 123 ? 104.596 142.220 153.343 1.00 69.14  ? 105 PHE E CD1   1 
ATOM   11713 C CD2   . PHE F 2 123 ? 102.888 140.584 153.616 1.00 69.14  ? 105 PHE E CD2   1 
ATOM   11714 C CE1   . PHE F 2 123 ? 103.661 143.127 152.890 1.00 69.14  ? 105 PHE E CE1   1 
ATOM   11715 C CE2   . PHE F 2 123 ? 101.948 141.488 153.163 1.00 69.14  ? 105 PHE E CE2   1 
ATOM   11716 C CZ    . PHE F 2 123 ? 102.335 142.761 152.801 1.00 69.14  ? 105 PHE E CZ    1 
ATOM   11717 N N     . SER F 2 124 ? 107.621 137.486 153.041 1.00 78.16  ? 106 SER E N     1 
ATOM   11718 C CA    . SER F 2 124 ? 108.670 136.599 153.525 1.00 78.16  ? 106 SER E CA    1 
ATOM   11719 C C     . SER F 2 124 ? 110.001 137.339 153.551 1.00 78.16  ? 106 SER E C     1 
ATOM   11720 O O     . SER F 2 124 ? 110.286 138.167 152.683 1.00 78.16  ? 106 SER E O     1 
ATOM   11721 C CB    . SER F 2 124 ? 108.769 135.357 152.641 1.00 78.16  ? 106 SER E CB    1 
ATOM   11722 O OG    . SER F 2 124 ? 107.516 134.700 152.542 1.00 78.16  ? 106 SER E OG    1 
ATOM   11723 N N     . LEU F 2 125 ? 110.823 137.034 154.557 1.00 81.28  ? 107 LEU E N     1 
ATOM   11724 C CA    . LEU F 2 125 ? 112.034 137.807 154.810 1.00 81.28  ? 107 LEU E CA    1 
ATOM   11725 C C     . LEU F 2 125 ? 113.114 137.623 153.749 1.00 81.28  ? 107 LEU E C     1 
ATOM   11726 O O     . LEU F 2 125 ? 114.067 138.410 153.728 1.00 81.28  ? 107 LEU E O     1 
ATOM   11727 C CB    . LEU F 2 125 ? 112.596 137.445 156.188 1.00 81.28  ? 107 LEU E CB    1 
ATOM   11728 C CG    . LEU F 2 125 ? 111.699 137.749 157.395 1.00 81.28  ? 107 LEU E CG    1 
ATOM   11729 C CD1   . LEU F 2 125 ? 112.278 137.124 158.655 1.00 81.28  ? 107 LEU E CD1   1 
ATOM   11730 C CD2   . LEU F 2 125 ? 111.504 139.252 157.584 1.00 81.28  ? 107 LEU E CD2   1 
ATOM   11731 N N     . GLU F 2 126 ? 113.001 136.622 152.871 1.00 93.64  ? 108 GLU E N     1 
ATOM   11732 C CA    . GLU F 2 126 ? 113.972 136.452 151.795 1.00 93.64  ? 108 GLU E CA    1 
ATOM   11733 C C     . GLU F 2 126 ? 113.853 137.505 150.695 1.00 93.64  ? 108 GLU E C     1 
ATOM   11734 O O     . GLU F 2 126 ? 114.748 137.576 149.846 1.00 93.64  ? 108 GLU E O     1 
ATOM   11735 C CB    . GLU F 2 126 ? 113.826 135.060 151.166 1.00 93.64  ? 108 GLU E CB    1 
ATOM   11736 C CG    . GLU F 2 126 ? 113.907 133.880 152.139 1.00 93.64  ? 108 GLU E CG    1 
ATOM   11737 C CD    . GLU F 2 126 ? 115.215 133.825 152.905 1.00 93.64  ? 108 GLU E CD    1 
ATOM   11738 O OE1   . GLU F 2 126 ? 116.279 134.021 152.282 1.00 93.64  ? 108 GLU E OE1   1 
ATOM   11739 O OE2   . GLU F 2 126 ? 115.179 133.583 154.129 1.00 93.64  ? 108 GLU E OE2   1 
ATOM   11740 N N     . MET F 2 127 ? 112.790 138.310 150.680 1.00 91.18  ? 109 MET E N     1 
ATOM   11741 C CA    . MET F 2 127 ? 112.545 139.251 149.595 1.00 91.18  ? 109 MET E CA    1 
ATOM   11742 C C     . MET F 2 127 ? 111.686 140.389 150.122 1.00 91.18  ? 109 MET E C     1 
ATOM   11743 O O     . MET F 2 127 ? 111.021 140.262 151.153 1.00 91.18  ? 109 MET E O     1 
ATOM   11744 C CB    . MET F 2 127 ? 111.857 138.564 148.409 1.00 91.18  ? 109 MET E CB    1 
ATOM   11745 C CG    . MET F 2 127 ? 110.938 137.413 148.813 1.00 91.18  ? 109 MET E CG    1 
ATOM   11746 S SD    . MET F 2 127 ? 109.772 136.932 147.528 1.00 91.18  ? 109 MET E SD    1 
ATOM   11747 C CE    . MET F 2 127 ? 108.658 135.894 148.471 1.00 91.18  ? 109 MET E CE    1 
ATOM   11748 N N     . SER F 2 128 ? 111.710 141.506 149.399 1.00 84.65  ? 110 SER E N     1 
ATOM   11749 C CA    . SER F 2 128 ? 110.885 142.653 149.742 1.00 84.65  ? 110 SER E CA    1 
ATOM   11750 C C     . SER F 2 128 ? 109.483 142.488 149.163 1.00 84.65  ? 110 SER E C     1 
ATOM   11751 O O     . SER F 2 128 ? 109.244 141.673 148.269 1.00 84.65  ? 110 SER E O     1 
ATOM   11752 C CB    . SER F 2 128 ? 111.517 143.946 149.226 1.00 84.65  ? 110 SER E CB    1 
ATOM   11753 O OG    . SER F 2 128 ? 112.895 144.003 149.553 1.00 84.65  ? 110 SER E OG    1 
ATOM   11754 N N     . LYS F 2 129 ? 108.545 143.271 149.702 1.00 72.96  ? 111 LYS E N     1 
ATOM   11755 C CA    . LYS F 2 129 ? 107.176 143.235 149.196 1.00 72.96  ? 111 LYS E CA    1 
ATOM   11756 C C     . LYS F 2 129 ? 107.111 143.726 147.753 1.00 72.96  ? 111 LYS E C     1 
ATOM   11757 O O     . LYS F 2 129 ? 106.447 143.112 146.905 1.00 72.96  ? 111 LYS E O     1 
ATOM   11758 C CB    . LYS F 2 129 ? 106.259 144.055 150.115 1.00 72.96  ? 111 LYS E CB    1 
ATOM   11759 C CG    . LYS F 2 129 ? 106.545 145.559 150.180 1.00 72.96  ? 111 LYS E CG    1 
ATOM   11760 C CD    . LYS F 2 129 ? 105.756 146.246 151.289 1.00 72.96  ? 111 LYS E CD    1 
ATOM   11761 C CE    . LYS F 2 129 ? 106.466 146.184 152.630 1.00 72.96  ? 111 LYS E CE    1 
ATOM   11762 N NZ    . LYS F 2 129 ? 105.744 146.981 153.660 1.00 72.96  ? 111 LYS E NZ    1 
ATOM   11763 N N     . THR F 2 130 ? 107.830 144.807 147.444 1.00 76.67  ? 112 THR E N     1 
ATOM   11764 C CA    . THR F 2 130 ? 107.808 145.343 146.090 1.00 76.67  ? 112 THR E CA    1 
ATOM   11765 C C     . THR F 2 130 ? 108.518 144.418 145.113 1.00 76.67  ? 112 THR E C     1 
ATOM   11766 O O     . THR F 2 130 ? 108.115 144.335 143.951 1.00 76.67  ? 112 THR E O     1 
ATOM   11767 C CB    . THR F 2 130 ? 108.426 146.746 146.061 1.00 76.67  ? 112 THR E CB    1 
ATOM   11768 O OG1   . THR F 2 130 ? 108.181 147.350 144.785 1.00 76.67  ? 112 THR E OG1   1 
ATOM   11769 C CG2   . THR F 2 130 ? 109.933 146.715 146.321 1.00 76.67  ? 112 THR E CG2   1 
ATOM   11770 N N     . GLU F 2 131 ? 109.553 143.702 145.563 1.00 85.24  ? 113 GLU E N     1 
ATOM   11771 C CA    . GLU F 2 131 ? 110.263 142.784 144.678 1.00 85.24  ? 113 GLU E CA    1 
ATOM   11772 C C     . GLU F 2 131 ? 109.374 141.610 144.282 1.00 85.24  ? 113 GLU E C     1 
ATOM   11773 O O     . GLU F 2 131 ? 109.308 141.231 143.105 1.00 85.24  ? 113 GLU E O     1 
ATOM   11774 C CB    . GLU F 2 131 ? 111.541 142.290 145.358 1.00 85.24  ? 113 GLU E CB    1 
ATOM   11775 C CG    . GLU F 2 131 ? 112.617 141.816 144.393 1.00 85.24  ? 113 GLU E CG    1 
ATOM   11776 C CD    . GLU F 2 131 ? 113.315 142.956 143.676 1.00 85.24  ? 113 GLU E CD    1 
ATOM   11777 O OE1   . GLU F 2 131 ? 113.766 143.903 144.353 1.00 85.24  ? 113 GLU E OE1   1 
ATOM   11778 O OE2   . GLU F 2 131 ? 113.410 142.901 142.432 1.00 85.24  ? 113 GLU E OE2   1 
ATOM   11779 N N     . ALA F 2 132 ? 108.673 141.028 145.257 1.00 77.75  ? 114 ALA E N     1 
ATOM   11780 C CA    . ALA F 2 132 ? 107.741 139.950 144.953 1.00 77.75  ? 114 ALA E CA    1 
ATOM   11781 C C     . ALA F 2 132 ? 106.604 140.444 144.070 1.00 77.75  ? 114 ALA E C     1 
ATOM   11782 O O     . ALA F 2 132 ? 106.196 139.754 143.126 1.00 77.75  ? 114 ALA E O     1 
ATOM   11783 C CB    . ALA F 2 132 ? 107.193 139.353 146.246 1.00 77.75  ? 114 ALA E CB    1 
ATOM   11784 N N     . LEU F 2 133 ? 106.090 141.647 144.350 1.00 69.47  ? 115 LEU E N     1 
ATOM   11785 C CA    . LEU F 2 133 ? 104.979 142.166 143.559 1.00 69.47  ? 115 LEU E CA    1 
ATOM   11786 C C     . LEU F 2 133 ? 105.392 142.447 142.118 1.00 69.47  ? 115 LEU E C     1 
ATOM   11787 O O     . LEU F 2 133 ? 104.654 142.104 141.191 1.00 69.47  ? 115 LEU E O     1 
ATOM   11788 C CB    . LEU F 2 133 ? 104.404 143.424 144.209 1.00 69.47  ? 115 LEU E CB    1 
ATOM   11789 C CG    . LEU F 2 133 ? 103.537 143.243 145.459 1.00 69.47  ? 115 LEU E CG    1 
ATOM   11790 C CD1   . LEU F 2 133 ? 103.248 144.599 146.070 1.00 69.47  ? 115 LEU E CD1   1 
ATOM   11791 C CD2   . LEU F 2 133 ? 102.231 142.512 145.153 1.00 69.47  ? 115 LEU E CD2   1 
ATOM   11792 N N     . THR F 2 134 ? 106.567 143.049 141.896 1.00 77.13  ? 116 THR E N     1 
ATOM   11793 C CA    . THR F 2 134 ? 106.983 143.314 140.519 1.00 77.13  ? 116 THR E CA    1 
ATOM   11794 C C     . THR F 2 134 ? 107.364 142.030 139.793 1.00 77.13  ? 116 THR E C     1 
ATOM   11795 O O     . THR F 2 134 ? 107.158 141.931 138.578 1.00 77.13  ? 116 THR E O     1 
ATOM   11796 C CB    . THR F 2 134 ? 108.136 144.329 140.464 1.00 77.13  ? 116 THR E CB    1 
ATOM   11797 O OG1   . THR F 2 134 ? 108.369 144.711 139.102 1.00 77.13  ? 116 THR E OG1   1 
ATOM   11798 C CG2   . THR F 2 134 ? 109.430 143.789 141.056 1.00 77.13  ? 116 THR E CG2   1 
ATOM   11799 N N     . GLN F 2 135 ? 107.908 141.037 140.506 1.00 81.67  ? 117 GLN E N     1 
ATOM   11800 C CA    . GLN F 2 135 ? 108.193 139.753 139.872 1.00 81.67  ? 117 GLN E CA    1 
ATOM   11801 C C     . GLN F 2 135 ? 106.904 139.073 139.420 1.00 81.67  ? 117 GLN E C     1 
ATOM   11802 O O     . GLN F 2 135 ? 106.804 138.598 138.282 1.00 81.67  ? 117 GLN E O     1 
ATOM   11803 C CB    . GLN F 2 135 ? 108.971 138.861 140.840 1.00 81.67  ? 117 GLN E CB    1 
ATOM   11804 C CG    . GLN F 2 135 ? 109.625 137.635 140.204 1.00 81.67  ? 117 GLN E CG    1 
ATOM   11805 C CD    . GLN F 2 135 ? 110.005 136.582 141.226 1.00 81.67  ? 117 GLN E CD    1 
ATOM   11806 O OE1   . GLN F 2 135 ? 109.971 136.826 142.432 1.00 81.67  ? 117 GLN E OE1   1 
ATOM   11807 N NE2   . GLN F 2 135 ? 110.363 135.398 140.747 1.00 81.67  ? 117 GLN E NE2   1 
ATOM   11808 N N     . SER F 2 136 ? 105.897 139.029 140.299 1.00 70.18  ? 118 SER E N     1 
ATOM   11809 C CA    . SER F 2 136 ? 104.612 138.453 139.919 1.00 70.18  ? 118 SER E CA    1 
ATOM   11810 C C     . SER F 2 136 ? 103.923 139.277 138.837 1.00 70.18  ? 118 SER E C     1 
ATOM   11811 O O     . SER F 2 136 ? 103.188 138.725 138.011 1.00 70.18  ? 118 SER E O     1 
ATOM   11812 C CB    . SER F 2 136 ? 103.714 138.333 141.149 1.00 70.18  ? 118 SER E CB    1 
ATOM   11813 O OG    . SER F 2 136 ? 102.441 137.822 140.803 1.00 70.18  ? 118 SER E OG    1 
ATOM   11814 N N     . PHE F 2 137 ? 104.141 140.593 138.835 1.00 70.53  ? 119 PHE E N     1 
ATOM   11815 C CA    . PHE F 2 137 ? 103.596 141.455 137.793 1.00 70.53  ? 119 PHE E CA    1 
ATOM   11816 C C     . PHE F 2 137 ? 104.190 141.106 136.436 1.00 70.53  ? 119 PHE E C     1 
ATOM   11817 O O     . PHE F 2 137 ? 103.464 140.925 135.452 1.00 70.53  ? 119 PHE E O     1 
ATOM   11818 C CB    . PHE F 2 137 ? 103.881 142.913 138.165 1.00 70.53  ? 119 PHE E CB    1 
ATOM   11819 C CG    . PHE F 2 137 ? 103.277 143.928 137.233 1.00 70.53  ? 119 PHE E CG    1 
ATOM   11820 C CD1   . PHE F 2 137 ? 102.011 144.430 137.471 1.00 70.53  ? 119 PHE E CD1   1 
ATOM   11821 C CD2   . PHE F 2 137 ? 103.992 144.417 136.149 1.00 70.53  ? 119 PHE E CD2   1 
ATOM   11822 C CE1   . PHE F 2 137 ? 101.458 145.376 136.634 1.00 70.53  ? 119 PHE E CE1   1 
ATOM   11823 C CE2   . PHE F 2 137 ? 103.440 145.357 135.305 1.00 70.53  ? 119 PHE E CE2   1 
ATOM   11824 C CZ    . PHE F 2 137 ? 102.173 145.838 135.549 1.00 70.53  ? 119 PHE E CZ    1 
ATOM   11825 N N     . ARG F 2 138 ? 105.519 141.008 136.366 1.00 79.51  ? 120 ARG E N     1 
ATOM   11826 C CA    . ARG F 2 138 ? 106.172 140.721 135.094 1.00 79.51  ? 120 ARG E CA    1 
ATOM   11827 C C     . ARG F 2 138 ? 105.903 139.294 134.637 1.00 79.51  ? 120 ARG E C     1 
ATOM   11828 O O     . ARG F 2 138 ? 105.861 139.031 133.430 1.00 79.51  ? 120 ARG E O     1 
ATOM   11829 C CB    . ARG F 2 138 ? 107.679 140.959 135.199 1.00 79.51  ? 120 ARG E CB    1 
ATOM   11830 C CG    . ARG F 2 138 ? 108.085 142.399 135.578 1.00 79.51  ? 120 ARG E CG    1 
ATOM   11831 C CD    . ARG F 2 138 ? 108.808 143.196 134.470 1.00 79.51  ? 120 ARG E CD    1 
ATOM   11832 N NE    . ARG F 2 138 ? 109.923 142.509 133.819 1.00 79.51  ? 120 ARG E NE    1 
ATOM   11833 C CZ    . ARG F 2 138 ? 111.074 142.172 134.389 1.00 79.51  ? 120 ARG E CZ    1 
ATOM   11834 N NH1   . ARG F 2 138 ? 111.325 142.414 135.666 1.00 79.51  ? 120 ARG E NH1   1 
ATOM   11835 N NH2   . ARG F 2 138 ? 112.005 141.572 133.655 1.00 79.51  ? 120 ARG E NH2   1 
ATOM   11836 N N     . LYS F 2 139 ? 105.722 138.363 135.578 1.00 72.11  ? 121 LYS E N     1 
ATOM   11837 C CA    . LYS F 2 139 ? 105.453 136.974 135.222 1.00 72.11  ? 121 LYS E CA    1 
ATOM   11838 C C     . LYS F 2 139 ? 104.126 136.796 134.491 1.00 72.11  ? 121 LYS E C     1 
ATOM   11839 O O     . LYS F 2 139 ? 103.971 135.818 133.753 1.00 72.11  ? 121 LYS E O     1 
ATOM   11840 C CB    . LYS F 2 139 ? 105.470 136.112 136.485 1.00 72.11  ? 121 LYS E CB    1 
ATOM   11841 C CG    . LYS F 2 139 ? 105.699 134.626 136.237 1.00 72.11  ? 121 LYS E CG    1 
ATOM   11842 C CD    . LYS F 2 139 ? 105.364 133.766 137.459 1.00 72.11  ? 121 LYS E CD    1 
ATOM   11843 C CE    . LYS F 2 139 ? 106.373 133.923 138.596 1.00 72.11  ? 121 LYS E CE    1 
ATOM   11844 N NZ    . LYS F 2 139 ? 107.686 133.305 138.267 1.00 72.11  ? 121 LYS E NZ    1 
ATOM   11845 N N     . ALA F 2 140 ? 103.172 137.709 134.671 1.00 66.09  ? 122 ALA E N     1 
ATOM   11846 C CA    . ALA F 2 140 ? 101.847 137.595 134.074 1.00 66.09  ? 122 ALA E CA    1 
ATOM   11847 C C     . ALA F 2 140 ? 101.768 138.119 132.641 1.00 66.09  ? 122 ALA E C     1 
ATOM   11848 O O     . ALA F 2 140 ? 100.659 138.151 132.097 1.00 66.09  ? 122 ALA E O     1 
ATOM   11849 C CB    . ALA F 2 140 ? 100.825 138.342 134.932 1.00 66.09  ? 122 ALA E CB    1 
ATOM   11850 N N     . ILE F 2 141 ? 102.882 138.526 132.029 1.00 71.89  ? 123 ILE E N     1 
ATOM   11851 C CA    . ILE F 2 141 ? 102.910 139.105 130.685 1.00 71.89  ? 123 ILE E CA    1 
ATOM   11852 C C     . ILE F 2 141 ? 103.683 138.143 129.795 1.00 71.89  ? 123 ILE E C     1 
ATOM   11853 O O     . ILE F 2 141 ? 104.884 137.934 130.003 1.00 71.89  ? 123 ILE E O     1 
ATOM   11854 C CB    . ILE F 2 141 ? 103.560 140.502 130.666 1.00 71.89  ? 123 ILE E CB    1 
ATOM   11855 C CG1   . ILE F 2 141 ? 102.893 141.499 131.636 1.00 71.89  ? 123 ILE E CG1   1 
ATOM   11856 C CG2   . ILE F 2 141 ? 103.541 141.080 129.249 1.00 71.89  ? 123 ILE E CG2   1 
ATOM   11857 C CD1   . ILE F 2 141 ? 103.833 142.597 132.106 1.00 71.89  ? 123 ILE E CD1   1 
ATOM   11858 N N     . GLY F 2 142 ? 103.006 137.568 128.801 1.00 75.81  ? 124 GLY E N     1 
ATOM   11859 C CA    . GLY F 2 142 ? 103.614 136.607 127.901 1.00 75.81  ? 124 GLY E CA    1 
ATOM   11860 C C     . GLY F 2 142 ? 104.096 137.266 126.622 1.00 75.81  ? 124 GLY E C     1 
ATOM   11861 O O     . GLY F 2 142 ? 103.527 138.257 126.167 1.00 75.81  ? 124 GLY E O     1 
ATOM   11862 N N     . VAL F 2 143 ? 105.148 136.689 126.043 1.00 80.72  ? 125 VAL E N     1 
ATOM   11863 C CA    . VAL F 2 143 ? 105.732 137.143 124.785 1.00 80.72  ? 125 VAL E CA    1 
ATOM   11864 C C     . VAL F 2 143 ? 105.867 135.936 123.869 1.00 80.72  ? 125 VAL E C     1 
ATOM   11865 O O     . VAL F 2 143 ? 106.334 134.875 124.300 1.00 80.72  ? 125 VAL E O     1 
ATOM   11866 C CB    . VAL F 2 143 ? 107.099 137.823 125.000 1.00 80.72  ? 125 VAL E CB    1 
ATOM   11867 C CG1   . VAL F 2 143 ? 107.756 138.148 123.653 1.00 80.72  ? 125 VAL E CG1   1 
ATOM   11868 C CG2   . VAL F 2 143 ? 106.935 139.078 125.859 1.00 80.72  ? 125 VAL E CG2   1 
ATOM   11869 N N     . ARG F 2 144 ? 105.444 136.096 122.617 1.00 82.13  ? 126 ARG E N     1 
ATOM   11870 C CA    . ARG F 2 144 ? 105.564 135.050 121.605 1.00 82.13  ? 126 ARG E CA    1 
ATOM   11871 C C     . ARG F 2 144 ? 105.882 135.667 120.247 1.00 82.13  ? 126 ARG E C     1 
ATOM   11872 O O     . ARG F 2 144 ? 105.666 136.859 120.032 1.00 82.13  ? 126 ARG E O     1 
ATOM   11873 C CB    . ARG F 2 144 ? 104.279 134.213 121.531 1.00 82.13  ? 126 ARG E CB    1 
ATOM   11874 C CG    . ARG F 2 144 ? 102.987 135.006 121.326 1.00 82.13  ? 126 ARG E CG    1 
ATOM   11875 C CD    . ARG F 2 144 ? 101.862 134.100 120.851 1.00 82.13  ? 126 ARG E CD    1 
ATOM   11876 N NE    . ARG F 2 144 ? 100.559 134.755 120.922 1.00 82.13  ? 126 ARG E NE    1 
ATOM   11877 C CZ    . ARG F 2 144 ? 99.381  134.142 120.869 1.00 82.13  ? 126 ARG E CZ    1 
ATOM   11878 N NH1   . ARG F 2 144 ? 99.275  132.828 120.723 1.00 82.13  ? 126 ARG E NH1   1 
ATOM   11879 N NH2   . ARG F 2 144 ? 98.271  134.869 120.963 1.00 82.13  ? 126 ARG E NH2   1 
ATOM   11880 N N     . CYS F 2 256 ? 106.639 130.648 123.316 1.00 81.94  ? 238 CYS E N     1 
ATOM   11881 C CA    . CYS F 2 256 ? 105.971 131.331 124.460 1.00 81.94  ? 238 CYS E CA    1 
ATOM   11882 C C     . CYS F 2 256 ? 106.953 131.531 125.608 1.00 81.94  ? 238 CYS E C     1 
ATOM   11883 O O     . CYS F 2 256 ? 107.662 130.602 125.995 1.00 81.94  ? 238 CYS E O     1 
ATOM   11884 C CB    . CYS F 2 256 ? 104.763 130.524 124.934 1.00 81.94  ? 238 CYS E CB    1 
ATOM   11885 S SG    . CYS F 2 256 ? 103.785 129.804 123.596 1.00 81.94  ? 238 CYS E SG    1 
ATOM   11886 N N     . VAL F 2 257 ? 106.993 132.745 126.151 1.00 80.42  ? 239 VAL E N     1 
ATOM   11887 C CA    . VAL F 2 257 ? 107.898 133.063 127.249 1.00 80.42  ? 239 VAL E CA    1 
ATOM   11888 C C     . VAL F 2 257 ? 107.345 134.271 127.991 1.00 80.42  ? 239 VAL E C     1 
ATOM   11889 O O     . VAL F 2 257 ? 106.842 135.217 127.380 1.00 80.42  ? 239 VAL E O     1 
ATOM   11890 C CB    . VAL F 2 257 ? 109.339 133.309 126.737 1.00 80.42  ? 239 VAL E CB    1 
ATOM   11891 C CG1   . VAL F 2 257 ? 109.435 134.616 125.946 1.00 80.42  ? 239 VAL E CG1   1 
ATOM   11892 C CG2   . VAL F 2 257 ? 110.331 133.302 127.894 1.00 80.42  ? 239 VAL E CG2   1 
ATOM   11893 N N     . THR F 2 258 ? 107.435 134.222 129.317 1.00 78.53  ? 240 THR E N     1 
ATOM   11894 C CA    . THR F 2 258 ? 107.054 135.328 130.180 1.00 78.53  ? 240 THR E CA    1 
ATOM   11895 C C     . THR F 2 258 ? 108.228 136.285 130.355 1.00 78.53  ? 240 THR E C     1 
ATOM   11896 O O     . THR F 2 258 ? 109.381 135.949 130.078 1.00 78.53  ? 240 THR E O     1 
ATOM   11897 C CB    . THR F 2 258 ? 106.593 134.819 131.546 1.00 78.53  ? 240 THR E CB    1 
ATOM   11898 O OG1   . THR F 2 258 ? 107.701 134.230 132.237 1.00 78.53  ? 240 THR E OG1   1 
ATOM   11899 C CG2   . THR F 2 258 ? 105.486 133.786 131.389 1.00 78.53  ? 240 THR E CG2   1 
ATOM   11900 N N     . LEU F 2 259 ? 107.919 137.495 130.827 1.00 78.11  ? 241 LEU E N     1 
ATOM   11901 C CA    . LEU F 2 259 ? 108.967 138.500 130.987 1.00 78.11  ? 241 LEU E CA    1 
ATOM   11902 C C     . LEU F 2 259 ? 109.931 138.133 132.107 1.00 78.11  ? 241 LEU E C     1 
ATOM   11903 O O     . LEU F 2 259 ? 111.115 138.484 132.039 1.00 78.11  ? 241 LEU E O     1 
ATOM   11904 C CB    . LEU F 2 259 ? 108.365 139.886 131.242 1.00 78.11  ? 241 LEU E CB    1 
ATOM   11905 C CG    . LEU F 2 259 ? 108.545 140.869 130.080 1.00 78.11  ? 241 LEU E CG    1 
ATOM   11906 C CD1   . LEU F 2 259 ? 107.761 140.406 128.861 1.00 78.11  ? 241 LEU E CD1   1 
ATOM   11907 C CD2   . LEU F 2 259 ? 108.122 142.281 130.463 1.00 78.11  ? 241 LEU E CD2   1 
ATOM   11908 N N     . HIS F 2 260 ? 109.456 137.434 133.139 1.00 79.32  ? 242 HIS E N     1 
ATOM   11909 C CA    . HIS F 2 260 ? 110.374 136.926 134.153 1.00 79.32  ? 242 HIS E CA    1 
ATOM   11910 C C     . HIS F 2 260 ? 111.320 135.888 133.561 1.00 79.32  ? 242 HIS E C     1 
ATOM   11911 O O     . HIS F 2 260 ? 112.510 135.857 133.896 1.00 79.32  ? 242 HIS E O     1 
ATOM   11912 C CB    . HIS F 2 260 ? 109.596 136.330 135.324 1.00 79.32  ? 242 HIS E CB    1 
ATOM   11913 C CG    . HIS F 2 260 ? 110.457 135.582 136.291 1.00 79.32  ? 242 HIS E CG    1 
ATOM   11914 N ND1   . HIS F 2 260 ? 110.585 134.210 136.266 1.00 79.32  ? 242 HIS E ND1   1 
ATOM   11915 C CD2   . HIS F 2 260 ? 111.245 136.015 137.303 1.00 79.32  ? 242 HIS E CD2   1 
ATOM   11916 C CE1   . HIS F 2 260 ? 111.409 133.830 137.225 1.00 79.32  ? 242 HIS E CE1   1 
ATOM   11917 N NE2   . HIS F 2 260 ? 111.825 134.906 137.868 1.00 79.32  ? 242 HIS E NE2   1 
ATOM   11918 N N     . GLU F 2 261 ? 110.809 135.029 132.674 1.00 81.80  ? 243 GLU E N     1 
ATOM   11919 C CA    . GLU F 2 261 ? 111.681 134.083 131.986 1.00 81.80  ? 243 GLU E CA    1 
ATOM   11920 C C     . GLU F 2 261 ? 112.666 134.799 131.073 1.00 81.80  ? 243 GLU E C     1 
ATOM   11921 O O     . GLU F 2 261 ? 113.802 134.343 130.910 1.00 81.80  ? 243 GLU E O     1 
ATOM   11922 C CB    . GLU F 2 261 ? 110.851 133.079 131.186 1.00 81.80  ? 243 GLU E CB    1 
ATOM   11923 C CG    . GLU F 2 261 ? 110.294 131.937 132.019 1.00 81.80  ? 243 GLU E CG    1 
ATOM   11924 C CD    . GLU F 2 261 ? 109.188 131.183 131.308 1.00 81.80  ? 243 GLU E CD    1 
ATOM   11925 O OE1   . GLU F 2 261 ? 108.159 131.808 130.979 1.00 81.80  ? 243 GLU E OE1   1 
ATOM   11926 O OE2   . GLU F 2 261 ? 109.348 129.965 131.080 1.00 81.80  ? 243 GLU E OE2   1 
ATOM   11927 N N     . ILE F 2 262 ? 112.251 135.913 130.465 1.00 82.43  ? 244 ILE E N     1 
ATOM   11928 C CA    . ILE F 2 262 ? 113.173 136.702 129.654 1.00 82.43  ? 244 ILE E CA    1 
ATOM   11929 C C     . ILE F 2 262 ? 114.270 137.294 130.531 1.00 82.43  ? 244 ILE E C     1 
ATOM   11930 O O     . ILE F 2 262 ? 115.434 137.374 130.121 1.00 82.43  ? 244 ILE E O     1 
ATOM   11931 C CB    . ILE F 2 262 ? 112.400 137.790 128.877 1.00 82.43  ? 244 ILE E CB    1 
ATOM   11932 C CG1   . ILE F 2 262 ? 111.574 137.161 127.743 1.00 82.43  ? 244 ILE E CG1   1 
ATOM   11933 C CG2   . ILE F 2 262 ? 113.339 138.883 128.318 1.00 82.43  ? 244 ILE E CG2   1 
ATOM   11934 C CD1   . ILE F 2 262 ? 112.361 136.814 126.480 1.00 82.43  ? 244 ILE E CD1   1 
ATOM   11935 N N     . ASP F 2 263 ? 113.917 137.732 131.741 1.00 84.22  ? 245 ASP E N     1 
ATOM   11936 C CA    . ASP F 2 263 ? 114.928 138.234 132.666 1.00 84.22  ? 245 ASP E CA    1 
ATOM   11937 C C     . ASP F 2 263 ? 115.880 137.123 133.094 1.00 84.22  ? 245 ASP E C     1 
ATOM   11938 O O     . ASP F 2 263 ? 117.083 137.357 133.260 1.00 84.22  ? 245 ASP E O     1 
ATOM   11939 C CB    . ASP F 2 263 ? 114.254 138.860 133.885 1.00 84.22  ? 245 ASP E CB    1 
ATOM   11940 C CG    . ASP F 2 263 ? 115.127 139.897 134.566 1.00 84.22  ? 245 ASP E CG    1 
ATOM   11941 O OD1   . ASP F 2 263 ? 115.058 141.080 134.176 1.00 84.22  ? 245 ASP E OD1   1 
ATOM   11942 O OD2   . ASP F 2 263 ? 115.878 139.534 135.493 1.00 84.22  ? 245 ASP E OD2   1 
ATOM   11943 N N     . VAL F 2 264 ? 115.351 135.914 133.294 1.00 84.73  ? 246 VAL E N     1 
ATOM   11944 C CA    . VAL F 2 264 ? 116.193 134.770 133.640 1.00 84.73  ? 246 VAL E CA    1 
ATOM   11945 C C     . VAL F 2 264 ? 117.154 134.456 132.497 1.00 84.73  ? 246 VAL E C     1 
ATOM   11946 O O     . VAL F 2 264 ? 118.334 134.161 132.722 1.00 84.73  ? 246 VAL E O     1 
ATOM   11947 C CB    . VAL F 2 264 ? 115.317 133.552 134.005 1.00 84.73  ? 246 VAL E CB    1 
ATOM   11948 C CG1   . VAL F 2 264 ? 116.151 132.266 134.098 1.00 84.73  ? 246 VAL E CG1   1 
ATOM   11949 C CG2   . VAL F 2 264 ? 114.576 133.780 135.329 1.00 84.73  ? 246 VAL E CG2   1 
ATOM   11950 N N     . ILE F 2 265 ? 116.661 134.503 131.256 1.00 82.74  ? 247 ILE E N     1 
ATOM   11951 C CA    . ILE F 2 265 ? 117.500 134.212 130.095 1.00 82.74  ? 247 ILE E CA    1 
ATOM   11952 C C     . ILE F 2 265 ? 118.586 135.272 129.946 1.00 82.74  ? 247 ILE E C     1 
ATOM   11953 O O     . ILE F 2 265 ? 119.762 134.951 129.738 1.00 82.74  ? 247 ILE E O     1 
ATOM   11954 C CB    . ILE F 2 265 ? 116.632 134.103 128.823 1.00 82.74  ? 247 ILE E CB    1 
ATOM   11955 C CG1   . ILE F 2 265 ? 115.837 132.791 128.826 1.00 82.74  ? 247 ILE E CG1   1 
ATOM   11956 C CG2   . ILE F 2 265 ? 117.481 134.192 127.530 1.00 82.74  ? 247 ILE E CG2   1 
ATOM   11957 C CD1   . ILE F 2 265 ? 114.587 132.814 127.958 1.00 82.74  ? 247 ILE E CD1   1 
ATOM   11958 N N     . ASN F 2 266 ? 118.210 136.549 130.045 1.00 87.31  ? 248 ASN E N     1 
ATOM   11959 C CA    . ASN F 2 266 ? 119.165 137.617 129.770 1.00 87.31  ? 248 ASN E CA    1 
ATOM   11960 C C     . ASN F 2 266 ? 120.187 137.708 130.900 1.00 87.31  ? 248 ASN E C     1 
ATOM   11961 O O     . ASN F 2 266 ? 121.372 137.948 130.639 1.00 87.31  ? 248 ASN E O     1 
ATOM   11962 C CB    . ASN F 2 266 ? 118.383 138.931 129.557 1.00 87.31  ? 248 ASN E CB    1 
ATOM   11963 C CG    . ASN F 2 266 ? 119.262 140.171 129.242 1.00 87.31  ? 248 ASN E CG    1 
ATOM   11964 O OD1   . ASN F 2 266 ? 120.387 140.348 129.708 1.00 87.31  ? 248 ASN E OD1   1 
ATOM   11965 N ND2   . ASN F 2 266 ? 118.695 141.054 128.427 1.00 87.31  ? 248 ASN E ND2   1 
ATOM   11966 N N     . SER F 2 267 ? 119.753 137.523 132.144 1.00 87.08  ? 249 SER E N     1 
ATOM   11967 C CA    . SER F 2 267 ? 120.652 137.555 133.296 1.00 87.08  ? 249 SER E CA    1 
ATOM   11968 C C     . SER F 2 267 ? 121.688 136.437 133.212 1.00 87.08  ? 249 SER E C     1 
ATOM   11969 O O     . SER F 2 267 ? 122.776 136.627 132.671 1.00 87.08  ? 249 SER E O     1 
ATOM   11970 C CB    . SER F 2 267 ? 119.865 137.424 134.601 1.00 87.08  ? 249 SER E CB    1 
ATOM   11971 O OG    . SER F 2 267 ? 119.030 136.279 134.578 1.00 87.08  ? 249 SER E OG    1 
ATOM   11972 N N     . THR F 2 280 ? 113.046 136.617 145.472 1.00 95.11  ? 262 THR E N     1 
ATOM   11973 C CA    . THR F 2 280 ? 112.947 136.930 144.019 1.00 95.11  ? 262 THR E CA    1 
ATOM   11974 C C     . THR F 2 280 ? 114.234 136.504 143.309 1.00 95.11  ? 262 THR E C     1 
ATOM   11975 O O     . THR F 2 280 ? 114.230 135.551 142.528 1.00 95.11  ? 262 THR E O     1 
ATOM   11976 C CB    . THR F 2 280 ? 112.675 138.433 143.790 1.00 95.11  ? 262 THR E CB    1 
ATOM   11977 O OG1   . THR F 2 280 ? 111.398 138.774 144.342 1.00 95.11  ? 262 THR E OG1   1 
ATOM   11978 C CG2   . THR F 2 280 ? 112.676 138.781 142.304 1.00 95.11  ? 262 THR E CG2   1 
ATOM   11979 N N     . GLY F 2 281 ? 115.329 137.214 143.584 1.00 102.09 ? 263 GLY E N     1 
ATOM   11980 C CA    . GLY F 2 281 ? 116.635 136.900 143.045 1.00 102.09 ? 263 GLY E CA    1 
ATOM   11981 C C     . GLY F 2 281 ? 116.982 137.628 141.761 1.00 102.09 ? 263 GLY E C     1 
ATOM   11982 O O     . GLY F 2 281 ? 118.168 137.823 141.474 1.00 102.09 ? 263 GLY E O     1 
ATOM   11983 N N     . GLU F 2 282 ? 115.979 138.034 140.985 1.00 96.05  ? 264 GLU E N     1 
ATOM   11984 C CA    . GLU F 2 282 ? 116.180 138.781 139.741 1.00 96.05  ? 264 GLU E CA    1 
ATOM   11985 C C     . GLU F 2 282 ? 116.190 140.287 140.001 1.00 96.05  ? 264 GLU E C     1 
ATOM   11986 O O     . GLU F 2 282 ? 115.497 141.052 139.333 1.00 96.05  ? 264 GLU E O     1 
ATOM   11987 C CB    . GLU F 2 282 ? 115.089 138.412 138.739 1.00 96.05  ? 264 GLU E CB    1 
ATOM   11988 C CG    . GLU F 2 282 ? 115.038 136.935 138.334 1.00 96.05  ? 264 GLU E CG    1 
ATOM   11989 C CD    . GLU F 2 282 ? 116.247 136.486 137.538 1.00 96.05  ? 264 GLU E CD    1 
ATOM   11990 O OE1   . GLU F 2 282 ? 116.783 137.293 136.752 1.00 96.05  ? 264 GLU E OE1   1 
ATOM   11991 O OE2   . GLU F 2 282 ? 116.662 135.318 137.697 1.00 96.05  ? 264 GLU E OE2   1 
ATOM   11992 N N     . ILE F 2 283 ? 116.996 140.724 140.969 1.00 96.59  ? 265 ILE E N     1 
ATOM   11993 C CA    . ILE F 2 283 ? 117.018 142.126 141.409 1.00 96.59  ? 265 ILE E CA    1 
ATOM   11994 C C     . ILE F 2 283 ? 118.023 142.836 140.507 1.00 96.59  ? 265 ILE E C     1 
ATOM   11995 O O     . ILE F 2 283 ? 119.228 142.836 140.756 1.00 96.59  ? 265 ILE E O     1 
ATOM   11996 C CB    . ILE F 2 283 ? 117.361 142.258 142.893 1.00 96.59  ? 265 ILE E CB    1 
ATOM   11997 C CG1   . ILE F 2 283 ? 116.344 141.478 143.747 1.00 96.59  ? 265 ILE E CG1   1 
ATOM   11998 C CG2   . ILE F 2 283 ? 117.428 143.747 143.305 1.00 96.59  ? 265 ILE E CG2   1 
ATOM   11999 C CD1   . ILE F 2 283 ? 116.931 140.274 144.448 1.00 96.59  ? 265 ILE E CD1   1 
ATOM   12000 N N     . ARG F 2 284 ? 117.510 143.453 139.441 1.00 95.46  ? 266 ARG E N     1 
ATOM   12001 C CA    . ARG F 2 284 ? 118.370 143.919 138.359 1.00 95.46  ? 266 ARG E CA    1 
ATOM   12002 C C     . ARG F 2 284 ? 117.579 144.944 137.538 1.00 95.46  ? 266 ARG E C     1 
ATOM   12003 O O     . ARG F 2 284 ? 116.691 144.565 136.770 1.00 95.46  ? 266 ARG E O     1 
ATOM   12004 C CB    . ARG F 2 284 ? 118.825 142.709 137.555 1.00 95.46  ? 266 ARG E CB    1 
ATOM   12005 C CG    . ARG F 2 284 ? 119.419 142.930 136.178 1.00 95.46  ? 266 ARG E CG    1 
ATOM   12006 C CD    . ARG F 2 284 ? 119.842 141.626 135.458 1.00 95.46  ? 266 ARG E CD    1 
ATOM   12007 N NE    . ARG F 2 284 ? 119.871 140.438 136.311 1.00 95.46  ? 266 ARG E NE    1 
ATOM   12008 C CZ    . ARG F 2 284 ? 120.913 139.999 137.007 1.00 95.46  ? 266 ARG E CZ    1 
ATOM   12009 N NH1   . ARG F 2 284 ? 122.071 140.646 137.027 1.00 95.46  ? 266 ARG E NH1   1 
ATOM   12010 N NH2   . ARG F 2 284 ? 120.787 138.882 137.718 1.00 95.46  ? 266 ARG E NH2   1 
ATOM   12011 N N     . SER F 2 285 ? 117.920 146.228 137.697 1.00 96.48  ? 267 SER E N     1 
ATOM   12012 C CA    . SER F 2 285 ? 117.136 147.324 137.125 1.00 96.48  ? 267 SER E CA    1 
ATOM   12013 C C     . SER F 2 285 ? 117.601 147.756 135.734 1.00 96.48  ? 267 SER E C     1 
ATOM   12014 O O     . SER F 2 285 ? 116.768 148.094 134.877 1.00 96.48  ? 267 SER E O     1 
ATOM   12015 C CB    . SER F 2 285 ? 117.160 148.528 138.072 1.00 96.48  ? 267 SER E CB    1 
ATOM   12016 O OG    . SER F 2 285 ? 116.507 148.224 139.293 1.00 96.48  ? 267 SER E OG    1 
ATOM   12017 N N     . GLU F 2 286 ? 118.913 147.786 135.495 1.00 99.79  ? 268 GLU E N     1 
ATOM   12018 C CA    . GLU F 2 286 ? 119.412 148.230 134.197 1.00 99.79  ? 268 GLU E CA    1 
ATOM   12019 C C     . GLU F 2 286 ? 118.994 147.268 133.091 1.00 99.79  ? 268 GLU E C     1 
ATOM   12020 O O     . GLU F 2 286 ? 118.567 147.695 132.009 1.00 99.79  ? 268 GLU E O     1 
ATOM   12021 C CB    . GLU F 2 286 ? 120.933 148.378 134.250 1.00 99.79  ? 268 GLU E CB    1 
ATOM   12022 C CG    . GLU F 2 286 ? 121.423 149.467 135.210 1.00 99.79  ? 268 GLU E CG    1 
ATOM   12023 C CD    . GLU F 2 286 ? 121.762 148.931 136.591 1.00 99.79  ? 268 GLU E CD    1 
ATOM   12024 O OE1   . GLU F 2 286 ? 121.032 148.043 137.079 1.00 99.79  ? 268 GLU E OE1   1 
ATOM   12025 O OE2   . GLU F 2 286 ? 122.760 149.393 137.184 1.00 99.79  ? 268 GLU E OE2   1 
ATOM   12026 N N     . VAL F 2 287 ? 119.064 145.963 133.358 1.00 97.34  ? 269 VAL E N     1 
ATOM   12027 C CA    . VAL F 2 287 ? 118.644 144.998 132.350 1.00 97.34  ? 269 VAL E CA    1 
ATOM   12028 C C     . VAL F 2 287 ? 117.121 144.919 132.286 1.00 97.34  ? 269 VAL E C     1 
ATOM   12029 O O     . VAL F 2 287 ? 116.571 144.488 131.271 1.00 97.34  ? 269 VAL E O     1 
ATOM   12030 C CB    . VAL F 2 287 ? 119.283 143.623 132.605 1.00 97.34  ? 269 VAL E CB    1 
ATOM   12031 C CG1   . VAL F 2 287 ? 118.962 142.635 131.486 1.00 97.34  ? 269 VAL E CG1   1 
ATOM   12032 C CG2   . VAL F 2 287 ? 120.803 143.787 132.831 1.00 97.34  ? 269 VAL E CG2   1 
ATOM   12033 N N     . ARG F 2 288 ? 116.409 145.338 133.341 1.00 90.27  ? 270 ARG E N     1 
ATOM   12034 C CA    . ARG F 2 288 ? 114.967 145.542 133.196 1.00 90.27  ? 270 ARG E CA    1 
ATOM   12035 C C     . ARG F 2 288 ? 114.673 146.626 132.166 1.00 90.27  ? 270 ARG E C     1 
ATOM   12036 O O     . ARG F 2 288 ? 113.788 146.458 131.316 1.00 90.27  ? 270 ARG E O     1 
ATOM   12037 C CB    . ARG F 2 288 ? 114.312 145.910 134.532 1.00 90.27  ? 270 ARG E CB    1 
ATOM   12038 C CG    . ARG F 2 288 ? 113.832 144.741 135.395 1.00 90.27  ? 270 ARG E CG    1 
ATOM   12039 C CD    . ARG F 2 288 ? 113.609 145.169 136.850 1.00 90.27  ? 270 ARG E CD    1 
ATOM   12040 N NE    . ARG F 2 288 ? 113.478 144.044 137.776 1.00 90.27  ? 270 ARG E NE    1 
ATOM   12041 C CZ    . ARG F 2 288 ? 112.366 143.638 138.382 1.00 90.27  ? 270 ARG E CZ    1 
ATOM   12042 N NH1   . ARG F 2 288 ? 111.191 144.224 138.183 1.00 90.27  ? 270 ARG E NH1   1 
ATOM   12043 N NH2   . ARG F 2 288 ? 112.433 142.608 139.220 1.00 90.27  ? 270 ARG E NH2   1 
ATOM   12044 N N     . GLU F 2 289 ? 115.414 147.740 132.219 1.00 96.11  ? 271 GLU E N     1 
ATOM   12045 C CA    . GLU F 2 289 ? 115.266 148.771 131.191 1.00 96.11  ? 271 GLU E CA    1 
ATOM   12046 C C     . GLU F 2 289 ? 115.638 148.236 129.812 1.00 96.11  ? 271 GLU E C     1 
ATOM   12047 O O     . GLU F 2 289 ? 114.970 148.549 128.814 1.00 96.11  ? 271 GLU E O     1 
ATOM   12048 C CB    . GLU F 2 289 ? 116.124 149.990 131.531 1.00 96.11  ? 271 GLU E CB    1 
ATOM   12049 C CG    . GLU F 2 289 ? 115.643 150.799 132.723 1.00 96.11  ? 271 GLU E CG    1 
ATOM   12050 C CD    . GLU F 2 289 ? 114.728 151.932 132.314 1.00 96.11  ? 271 GLU E CD    1 
ATOM   12051 O OE1   . GLU F 2 289 ? 115.230 152.919 131.737 1.00 96.11  ? 271 GLU E OE1   1 
ATOM   12052 O OE2   . GLU F 2 289 ? 113.509 151.834 132.561 1.00 96.11  ? 271 GLU E OE2   1 
ATOM   12053 N N     . GLN F 2 290 ? 116.706 147.431 129.740 1.00 97.08  ? 272 GLN E N     1 
ATOM   12054 C CA    . GLN F 2 290 ? 117.112 146.838 128.465 1.00 97.08  ? 272 GLN E CA    1 
ATOM   12055 C C     . GLN F 2 290 ? 116.023 145.929 127.908 1.00 97.08  ? 272 GLN E C     1 
ATOM   12056 O O     . GLN F 2 290 ? 115.732 145.962 126.708 1.00 97.08  ? 272 GLN E O     1 
ATOM   12057 C CB    . GLN F 2 290 ? 118.392 146.022 128.622 1.00 97.08  ? 272 GLN E CB    1 
ATOM   12058 C CG    . GLN F 2 290 ? 119.654 146.820 128.877 1.00 97.08  ? 272 GLN E CG    1 
ATOM   12059 C CD    . GLN F 2 290 ? 120.806 145.942 129.325 1.00 97.08  ? 272 GLN E CD    1 
ATOM   12060 O OE1   . GLN F 2 290 ? 120.821 144.739 129.065 1.00 97.08  ? 272 GLN E OE1   1 
ATOM   12061 N NE2   . GLN F 2 290 ? 121.781 146.542 129.997 1.00 97.08  ? 272 GLN E NE2   1 
ATOM   12062 N N     . ILE F 2 291 ? 115.427 145.098 128.768 1.00 91.56  ? 273 ILE E N     1 
ATOM   12063 C CA    . ILE F 2 291 ? 114.377 144.178 128.344 1.00 91.56  ? 273 ILE E CA    1 
ATOM   12064 C C     . ILE F 2 291 ? 113.167 144.958 127.860 1.00 91.56  ? 273 ILE E C     1 
ATOM   12065 O O     . ILE F 2 291 ? 112.548 144.597 126.853 1.00 91.56  ? 273 ILE E O     1 
ATOM   12066 C CB    . ILE F 2 291 ? 114.011 143.210 129.490 1.00 91.56  ? 273 ILE E CB    1 
ATOM   12067 C CG1   . ILE F 2 291 ? 115.144 142.207 129.743 1.00 91.56  ? 273 ILE E CG1   1 
ATOM   12068 C CG2   . ILE F 2 291 ? 112.707 142.443 129.187 1.00 91.56  ? 273 ILE E CG2   1 
ATOM   12069 C CD1   . ILE F 2 291 ? 115.146 141.612 131.146 1.00 91.56  ? 273 ILE E CD1   1 
ATOM   12070 N N     . ASP F 2 292 ? 112.809 146.031 128.575 1.00 95.97  ? 274 ASP E N     1 
ATOM   12071 C CA    . ASP F 2 292 ? 111.676 146.855 128.164 1.00 95.97  ? 274 ASP E CA    1 
ATOM   12072 C C     . ASP F 2 292 ? 111.918 147.481 126.796 1.00 95.97  ? 274 ASP E C     1 
ATOM   12073 O O     . ASP F 2 292 ? 111.045 147.431 125.923 1.00 95.97  ? 274 ASP E O     1 
ATOM   12074 C CB    . ASP F 2 292 ? 111.413 147.934 129.215 1.00 95.97  ? 274 ASP E CB    1 
ATOM   12075 C CG    . ASP F 2 292 ? 110.217 148.808 128.876 1.00 95.97  ? 274 ASP E CG    1 
ATOM   12076 O OD1   . ASP F 2 292 ? 110.353 149.722 128.034 1.00 95.97  ? 274 ASP E OD1   1 
ATOM   12077 O OD2   . ASP F 2 292 ? 109.135 148.579 129.455 1.00 95.97  ? 274 ASP E OD2   1 
ATOM   12078 N N     . THR F 2 293 ? 113.119 148.022 126.571 1.00 95.76  ? 275 THR E N     1 
ATOM   12079 C CA    . THR F 2 293 ? 113.433 148.608 125.269 1.00 95.76  ? 275 THR E CA    1 
ATOM   12080 C C     . THR F 2 293 ? 113.445 147.552 124.167 1.00 95.76  ? 275 THR E C     1 
ATOM   12081 O O     . THR F 2 293 ? 112.935 147.785 123.061 1.00 95.76  ? 275 THR E O     1 
ATOM   12082 C CB    . THR F 2 293 ? 114.784 149.320 125.330 1.00 95.76  ? 275 THR E CB    1 
ATOM   12083 O OG1   . THR F 2 293 ? 115.732 148.487 126.005 1.00 95.76  ? 275 THR E OG1   1 
ATOM   12084 C CG2   . THR F 2 293 ? 114.658 150.635 126.077 1.00 95.76  ? 275 THR E CG2   1 
ATOM   12085 N N     . LYS F 2 294 ? 114.007 146.376 124.452 1.00 95.54  ? 276 LYS E N     1 
ATOM   12086 C CA    . LYS F 2 294 ? 114.189 145.395 123.388 1.00 95.54  ? 276 LYS E CA    1 
ATOM   12087 C C     . LYS F 2 294 ? 112.855 144.748 123.011 1.00 95.54  ? 276 LYS E C     1 
ATOM   12088 O O     . LYS F 2 294 ? 112.534 144.618 121.817 1.00 95.54  ? 276 LYS E O     1 
ATOM   12089 C CB    . LYS F 2 294 ? 115.268 144.373 123.785 1.00 95.54  ? 276 LYS E CB    1 
ATOM   12090 C CG    . LYS F 2 294 ? 115.090 142.921 123.334 1.00 95.54  ? 276 LYS E CG    1 
ATOM   12091 C CD    . LYS F 2 294 ? 116.359 142.080 123.615 1.00 95.54  ? 276 LYS E CD    1 
ATOM   12092 C CE    . LYS F 2 294 ? 116.776 141.959 125.070 1.00 95.54  ? 276 LYS E CE    1 
ATOM   12093 N NZ    . LYS F 2 294 ? 118.036 141.177 125.135 1.00 95.54  ? 276 LYS E NZ    1 
ATOM   12094 N N     . VAL F 2 295 ? 112.032 144.399 124.007 1.00 93.45  ? 277 VAL E N     1 
ATOM   12095 C CA    . VAL F 2 295 ? 110.698 143.898 123.689 1.00 93.45  ? 277 VAL E CA    1 
ATOM   12096 C C     . VAL F 2 295 ? 109.835 145.006 123.097 1.00 93.45  ? 277 VAL E C     1 
ATOM   12097 O O     . VAL F 2 295 ? 108.913 144.724 122.327 1.00 93.45  ? 277 VAL E O     1 
ATOM   12098 C CB    . VAL F 2 295 ? 110.011 143.257 124.914 1.00 93.45  ? 277 VAL E CB    1 
ATOM   12099 C CG1   . VAL F 2 295 ? 110.843 142.099 125.468 1.00 93.45  ? 277 VAL E CG1   1 
ATOM   12100 C CG2   . VAL F 2 295 ? 109.677 144.290 125.984 1.00 93.45  ? 277 VAL E CG2   1 
ATOM   12101 N N     . ALA F 2 296 ? 110.111 146.277 123.421 1.00 98.09  ? 278 ALA E N     1 
ATOM   12102 C CA    . ALA F 2 296 ? 109.385 147.365 122.774 1.00 98.09  ? 278 ALA E CA    1 
ATOM   12103 C C     . ALA F 2 296 ? 109.691 147.431 121.284 1.00 98.09  ? 278 ALA E C     1 
ATOM   12104 O O     . ALA F 2 296 ? 108.778 147.625 120.470 1.00 98.09  ? 278 ALA E O     1 
ATOM   12105 C CB    . ALA F 2 296 ? 109.716 148.697 123.448 1.00 98.09  ? 278 ALA E CB    1 
ATOM   12106 N N     . GLU F 2 297 ? 110.968 147.282 120.901 1.00 100.42 ? 279 GLU E N     1 
ATOM   12107 C CA    . GLU F 2 297 ? 111.279 147.341 119.472 1.00 100.42 ? 279 GLU E CA    1 
ATOM   12108 C C     . GLU F 2 297 ? 110.737 146.110 118.753 1.00 100.42 ? 279 GLU E C     1 
ATOM   12109 O O     . GLU F 2 297 ? 110.321 146.205 117.593 1.00 100.42 ? 279 GLU E O     1 
ATOM   12110 C CB    . GLU F 2 297 ? 112.789 147.583 119.228 1.00 100.42 ? 279 GLU E CB    1 
ATOM   12111 C CG    . GLU F 2 297 ? 113.901 146.551 119.596 1.00 100.42 ? 279 GLU E CG    1 
ATOM   12112 C CD    . GLU F 2 297 ? 113.798 145.149 118.997 1.00 100.42 ? 279 GLU E CD    1 
ATOM   12113 O OE1   . GLU F 2 297 ? 114.144 144.173 119.691 1.00 100.42 ? 279 GLU E OE1   1 
ATOM   12114 O OE2   . GLU F 2 297 ? 113.392 145.033 117.822 1.00 100.42 ? 279 GLU E OE2   1 
ATOM   12115 N N     . TRP F 2 298 ? 110.714 144.946 119.422 1.00 98.95  ? 280 TRP E N     1 
ATOM   12116 C CA    . TRP F 2 298 ? 110.054 143.795 118.804 1.00 98.95  ? 280 TRP E CA    1 
ATOM   12117 C C     . TRP F 2 298 ? 108.552 144.020 118.659 1.00 98.95  ? 280 TRP E C     1 
ATOM   12118 O O     . TRP F 2 298 ? 107.960 143.624 117.647 1.00 98.95  ? 280 TRP E O     1 
ATOM   12119 C CB    . TRP F 2 298 ? 110.305 142.497 119.583 1.00 98.95  ? 280 TRP E CB    1 
ATOM   12120 C CG    . TRP F 2 298 ? 111.693 141.911 119.518 1.00 98.95  ? 280 TRP E CG    1 
ATOM   12121 C CD1   . TRP F 2 298 ? 112.523 141.872 118.431 1.00 98.95  ? 280 TRP E CD1   1 
ATOM   12122 C CD2   . TRP F 2 298 ? 112.355 141.167 120.548 1.00 98.95  ? 280 TRP E CD2   1 
ATOM   12123 N NE1   . TRP F 2 298 ? 113.680 141.204 118.741 1.00 98.95  ? 280 TRP E NE1   1 
ATOM   12124 C CE2   . TRP F 2 298 ? 113.600 140.754 120.032 1.00 98.95  ? 280 TRP E CE2   1 
ATOM   12125 C CE3   . TRP F 2 298 ? 112.023 140.826 121.862 1.00 98.95  ? 280 TRP E CE3   1 
ATOM   12126 C CZ2   . TRP F 2 298 ? 114.515 140.026 120.789 1.00 98.95  ? 280 TRP E CZ2   1 
ATOM   12127 C CZ3   . TRP F 2 298 ? 112.934 140.107 122.611 1.00 98.95  ? 280 TRP E CZ3   1 
ATOM   12128 C CH2   . TRP F 2 298 ? 114.158 139.706 122.070 1.00 98.95  ? 280 TRP E CH2   1 
ATOM   12129 N N     . ARG F 2 299 ? 107.917 144.637 119.658 1.00 98.18  ? 281 ARG E N     1 
ATOM   12130 C CA    . ARG F 2 299 ? 106.482 144.893 119.586 1.00 98.18  ? 281 ARG E CA    1 
ATOM   12131 C C     . ARG F 2 299 ? 106.154 145.863 118.458 1.00 98.18  ? 281 ARG E C     1 
ATOM   12132 O O     . ARG F 2 299 ? 105.175 145.672 117.728 1.00 98.18  ? 281 ARG E O     1 
ATOM   12133 C CB    . ARG F 2 299 ? 105.986 145.438 120.927 1.00 98.18  ? 281 ARG E CB    1 
ATOM   12134 C CG    . ARG F 2 299 ? 104.476 145.374 121.125 1.00 98.18  ? 281 ARG E CG    1 
ATOM   12135 C CD    . ARG F 2 299 ? 103.939 146.633 121.796 1.00 98.18  ? 281 ARG E CD    1 
ATOM   12136 N NE    . ARG F 2 299 ? 104.603 146.916 123.066 1.00 98.18  ? 281 ARG E NE    1 
ATOM   12137 C CZ    . ARG F 2 299 ? 104.384 147.980 123.832 1.00 98.18  ? 281 ARG E CZ    1 
ATOM   12138 N NH1   . ARG F 2 299 ? 103.510 148.920 123.498 1.00 98.18  ? 281 ARG E NH1   1 
ATOM   12139 N NH2   . ARG F 2 299 ? 105.064 148.108 124.969 1.00 98.18  ? 281 ARG E NH2   1 
ATOM   12140 N N     . GLU F 2 300 ? 106.965 146.911 118.301 1.00 103.51 ? 282 GLU E N     1 
ATOM   12141 C CA    . GLU F 2 300 ? 106.744 147.856 117.210 1.00 103.51 ? 282 GLU E CA    1 
ATOM   12142 C C     . GLU F 2 300 ? 107.036 147.221 115.856 1.00 103.51 ? 282 GLU E C     1 
ATOM   12143 O O     . GLU F 2 300 ? 106.297 147.442 114.889 1.00 103.51 ? 282 GLU E O     1 
ATOM   12144 C CB    . GLU F 2 300 ? 107.607 149.101 117.415 1.00 103.51 ? 282 GLU E CB    1 
ATOM   12145 C CG    . GLU F 2 300 ? 107.195 149.944 118.612 1.00 103.51 ? 282 GLU E CG    1 
ATOM   12146 C CD    . GLU F 2 300 ? 108.101 151.142 118.822 1.00 103.51 ? 282 GLU E CD    1 
ATOM   12147 O OE1   . GLU F 2 300 ? 109.146 151.228 118.144 1.00 103.51 ? 282 GLU E OE1   1 
ATOM   12148 O OE2   . GLU F 2 300 ? 107.769 151.998 119.670 1.00 103.51 ? 282 GLU E OE2   1 
ATOM   12149 N N     . GLU F 2 301 ? 108.106 146.430 115.764 1.00 103.82 ? 283 GLU E N     1 
ATOM   12150 C CA    . GLU F 2 301 ? 108.484 145.806 114.502 1.00 103.82 ? 283 GLU E CA    1 
ATOM   12151 C C     . GLU F 2 301 ? 107.599 144.623 114.127 1.00 103.82 ? 283 GLU E C     1 
ATOM   12152 O O     . GLU F 2 301 ? 107.604 144.216 112.961 1.00 103.82 ? 283 GLU E O     1 
ATOM   12153 C CB    . GLU F 2 301 ? 109.942 145.346 114.565 1.00 103.82 ? 283 GLU E CB    1 
ATOM   12154 C CG    . GLU F 2 301 ? 110.952 146.480 114.462 1.00 103.82 ? 283 GLU E CG    1 
ATOM   12155 C CD    . GLU F 2 301 ? 112.374 146.017 114.711 1.00 103.82 ? 283 GLU E CD    1 
ATOM   12156 O OE1   . GLU F 2 301 ? 112.713 144.890 114.294 1.00 103.82 ? 283 GLU E OE1   1 
ATOM   12157 O OE2   . GLU F 2 301 ? 113.152 146.780 115.322 1.00 103.82 ? 283 GLU E OE2   1 
ATOM   12158 N N     . GLY F 2 302 ? 106.844 144.064 115.073 1.00 106.34 ? 284 GLY E N     1 
ATOM   12159 C CA    . GLY F 2 302 ? 106.001 142.921 114.780 1.00 106.34 ? 284 GLY E CA    1 
ATOM   12160 C C     . GLY F 2 302 ? 106.719 141.593 114.701 1.00 106.34 ? 284 GLY E C     1 
ATOM   12161 O O     . GLY F 2 302 ? 106.141 140.623 114.202 1.00 106.34 ? 284 GLY E O     1 
ATOM   12162 N N     . LYS F 2 303 ? 107.965 141.515 115.179 1.00 102.35 ? 285 LYS E N     1 
ATOM   12163 C CA    . LYS F 2 303 ? 108.697 140.253 115.165 1.00 102.35 ? 285 LYS E CA    1 
ATOM   12164 C C     . LYS F 2 303 ? 108.234 139.311 116.267 1.00 102.35 ? 285 LYS E C     1 
ATOM   12165 O O     . LYS F 2 303 ? 108.249 138.089 116.075 1.00 102.35 ? 285 LYS E O     1 
ATOM   12166 C CB    . LYS F 2 303 ? 110.200 140.511 115.304 1.00 102.35 ? 285 LYS E CB    1 
ATOM   12167 C CG    . LYS F 2 303 ? 110.832 141.275 114.142 1.00 102.35 ? 285 LYS E CG    1 
ATOM   12168 C CD    . LYS F 2 303 ? 111.054 140.384 112.928 1.00 102.35 ? 285 LYS E CD    1 
ATOM   12169 C CE    . LYS F 2 303 ? 111.545 141.187 111.737 1.00 102.35 ? 285 LYS E CE    1 
ATOM   12170 N NZ    . LYS F 2 303 ? 110.422 141.808 110.984 1.00 102.35 ? 285 LYS E NZ    1 
ATOM   12171 N N     . ALA F 2 304 ? 107.829 139.852 117.416 1.00 96.40  ? 286 ALA E N     1 
ATOM   12172 C CA    . ALA F 2 304 ? 107.355 139.060 118.547 1.00 96.40  ? 286 ALA E CA    1 
ATOM   12173 C C     . ALA F 2 304 ? 106.238 139.828 119.234 1.00 96.40  ? 286 ALA E C     1 
ATOM   12174 O O     . ALA F 2 304 ? 106.462 140.933 119.739 1.00 96.40  ? 286 ALA E O     1 
ATOM   12175 C CB    . ALA F 2 304 ? 108.489 138.761 119.530 1.00 96.40  ? 286 ALA E CB    1 
ATOM   12176 N N     . GLU F 2 305 ? 105.044 139.243 119.254 1.00 88.84  ? 287 GLU E N     1 
ATOM   12177 C CA    . GLU F 2 305 ? 103.878 139.892 119.830 1.00 88.84  ? 287 GLU E CA    1 
ATOM   12178 C C     . GLU F 2 305 ? 103.909 139.770 121.353 1.00 88.84  ? 287 GLU E C     1 
ATOM   12179 O O     . GLU F 2 305 ? 104.824 139.184 121.940 1.00 88.84  ? 287 GLU E O     1 
ATOM   12180 C CB    . GLU F 2 305 ? 102.598 139.291 119.249 1.00 88.84  ? 287 GLU E CB    1 
ATOM   12181 C CG    . GLU F 2 305 ? 102.499 139.377 117.731 1.00 88.84  ? 287 GLU E CG    1 
ATOM   12182 C CD    . GLU F 2 305 ? 103.039 138.144 117.030 1.00 88.84  ? 287 GLU E CD    1 
ATOM   12183 O OE1   . GLU F 2 305 ? 103.984 137.521 117.559 1.00 88.84  ? 287 GLU E OE1   1 
ATOM   12184 O OE2   . GLU F 2 305 ? 102.517 137.799 115.950 1.00 88.84  ? 287 GLU E OE2   1 
ATOM   12185 N N     . ILE F 2 306 ? 102.892 140.346 121.996 1.00 79.66  ? 288 ILE E N     1 
ATOM   12186 C CA    . ILE F 2 306 ? 102.747 140.370 123.447 1.00 79.66  ? 288 ILE E CA    1 
ATOM   12187 C C     . ILE F 2 306 ? 101.308 140.013 123.786 1.00 79.66  ? 288 ILE E C     1 
ATOM   12188 O O     . ILE F 2 306 ? 100.381 140.415 123.072 1.00 79.66  ? 288 ILE E O     1 
ATOM   12189 C CB    . ILE F 2 306 ? 103.128 141.751 124.028 1.00 79.66  ? 288 ILE E CB    1 
ATOM   12190 C CG1   . ILE F 2 306 ? 103.270 141.682 125.551 1.00 79.66  ? 288 ILE E CG1   1 
ATOM   12191 C CG2   . ILE F 2 306 ? 102.108 142.829 123.635 1.00 79.66  ? 288 ILE E CG2   1 
ATOM   12192 C CD1   . ILE F 2 306 ? 103.853 142.936 126.147 1.00 79.66  ? 288 ILE E CD1   1 
ATOM   12193 N N     . VAL F 2 307 ? 101.129 139.237 124.863 1.00 72.25  ? 289 VAL E N     1 
ATOM   12194 C CA    . VAL F 2 307 ? 99.824  138.828 125.350 1.00 72.25  ? 289 VAL E CA    1 
ATOM   12195 C C     . VAL F 2 307 ? 99.742  139.170 126.846 1.00 72.25  ? 289 VAL E C     1 
ATOM   12196 O O     . VAL F 2 307 ? 100.548 138.656 127.630 1.00 72.25  ? 289 VAL E O     1 
ATOM   12197 C CB    . VAL F 2 307 ? 99.532  137.336 125.110 1.00 72.25  ? 289 VAL E CB    1 
ATOM   12198 C CG1   . VAL F 2 307 ? 100.591 136.383 125.725 1.00 72.25  ? 289 VAL E CG1   1 
ATOM   12199 C CG2   . VAL F 2 307 ? 98.110  136.966 125.573 1.00 72.25  ? 289 VAL E CG2   1 
ATOM   12200 N N     . PRO F 2 308 ? 98.848  140.060 127.285 1.00 65.65  ? 290 PRO E N     1 
ATOM   12201 C CA    . PRO F 2 308 ? 98.636  140.197 128.733 1.00 65.65  ? 290 PRO E CA    1 
ATOM   12202 C C     . PRO F 2 308 ? 97.910  138.990 129.304 1.00 65.65  ? 290 PRO E C     1 
ATOM   12203 O O     . PRO F 2 308 ? 96.945  138.490 128.722 1.00 65.65  ? 290 PRO E O     1 
ATOM   12204 C CB    . PRO F 2 308 ? 97.791  141.470 128.856 1.00 65.65  ? 290 PRO E CB    1 
ATOM   12205 C CG    . PRO F 2 308 ? 98.029  142.209 127.611 1.00 65.65  ? 290 PRO E CG    1 
ATOM   12206 C CD    . PRO F 2 308 ? 98.191  141.170 126.566 1.00 65.65  ? 290 PRO E CD    1 
ATOM   12207 N N     . GLY F 2 309 ? 98.383  138.531 130.455 1.00 60.12  ? 291 GLY E N     1 
ATOM   12208 C CA    . GLY F 2 309 ? 97.815  137.409 131.176 1.00 60.12  ? 291 GLY E CA    1 
ATOM   12209 C C     . GLY F 2 309 ? 96.871  137.851 132.272 1.00 60.12  ? 291 GLY E C     1 
ATOM   12210 O O     . GLY F 2 309 ? 96.204  138.887 132.167 1.00 60.12  ? 291 GLY E O     1 
ATOM   12211 N N     . VAL F 2 310 ? 96.810  137.048 133.335 1.00 56.31  ? 292 VAL E N     1 
ATOM   12212 C CA    . VAL F 2 310 ? 95.951  137.288 134.491 1.00 56.31  ? 292 VAL E CA    1 
ATOM   12213 C C     . VAL F 2 310 ? 96.805  137.163 135.743 1.00 56.31  ? 292 VAL E C     1 
ATOM   12214 O O     . VAL F 2 310 ? 97.409  136.109 135.981 1.00 56.31  ? 292 VAL E O     1 
ATOM   12215 C CB    . VAL F 2 310 ? 94.769  136.305 134.542 1.00 56.31  ? 292 VAL E CB    1 
ATOM   12216 C CG1   . VAL F 2 310 ? 93.964  136.505 135.830 1.00 56.31  ? 292 VAL E CG1   1 
ATOM   12217 C CG2   . VAL F 2 310 ? 93.892  136.466 133.299 1.00 56.31  ? 292 VAL E CG2   1 
ATOM   12218 N N     . LEU F 2 311 ? 96.843  138.231 136.544 1.00 57.22  ? 293 LEU E N     1 
ATOM   12219 C CA    . LEU F 2 311 ? 97.549  138.260 137.822 1.00 57.22  ? 293 LEU E CA    1 
ATOM   12220 C C     . LEU F 2 311 ? 96.511  138.147 138.931 1.00 57.22  ? 293 LEU E C     1 
ATOM   12221 O O     . LEU F 2 311 ? 95.726  139.077 139.141 1.00 57.22  ? 293 LEU E O     1 
ATOM   12222 C CB    . LEU F 2 311 ? 98.363  139.547 137.954 1.00 57.22  ? 293 LEU E CB    1 
ATOM   12223 C CG    . LEU F 2 311 ? 98.892  139.962 139.333 1.00 57.22  ? 293 LEU E CG    1 
ATOM   12224 C CD1   . LEU F 2 311 ? 99.716  138.848 139.952 1.00 57.22  ? 293 LEU E CD1   1 
ATOM   12225 C CD2   . LEU F 2 311 ? 99.710  141.235 139.211 1.00 57.22  ? 293 LEU E CD2   1 
ATOM   12226 N N     . PHE F 2 312 ? 96.524  137.020 139.647 1.00 54.21  ? 294 PHE E N     1 
ATOM   12227 C CA    . PHE F 2 312 ? 95.587  136.754 140.733 1.00 54.21  ? 294 PHE E CA    1 
ATOM   12228 C C     . PHE F 2 312 ? 96.293  136.970 142.065 1.00 54.21  ? 294 PHE E C     1 
ATOM   12229 O O     . PHE F 2 312 ? 97.335  136.352 142.322 1.00 54.21  ? 294 PHE E O     1 
ATOM   12230 C CB    . PHE F 2 312 ? 95.038  135.332 140.651 1.00 54.21  ? 294 PHE E CB    1 
ATOM   12231 C CG    . PHE F 2 312 ? 93.992  135.031 141.685 1.00 54.21  ? 294 PHE E CG    1 
ATOM   12232 C CD1   . PHE F 2 312 ? 92.718  135.556 141.577 1.00 54.21  ? 294 PHE E CD1   1 
ATOM   12233 C CD2   . PHE F 2 312 ? 94.286  134.232 142.771 1.00 54.21  ? 294 PHE E CD2   1 
ATOM   12234 C CE1   . PHE F 2 312 ? 91.758  135.281 142.528 1.00 54.21  ? 294 PHE E CE1   1 
ATOM   12235 C CE2   . PHE F 2 312 ? 93.332  133.955 143.726 1.00 54.21  ? 294 PHE E CE2   1 
ATOM   12236 C CZ    . PHE F 2 312 ? 92.068  134.479 143.604 1.00 54.21  ? 294 PHE E CZ    1 
ATOM   12237 N N     . ILE F 2 313 ? 95.731  137.852 142.896 1.00 55.14  ? 295 ILE E N     1 
ATOM   12238 C CA    . ILE F 2 313 ? 96.210  138.115 144.254 1.00 55.14  ? 295 ILE E CA    1 
ATOM   12239 C C     . ILE F 2 313 ? 95.142  137.593 145.209 1.00 55.14  ? 295 ILE E C     1 
ATOM   12240 O O     . ILE F 2 313 ? 94.040  138.149 145.285 1.00 55.14  ? 295 ILE E O     1 
ATOM   12241 C CB    . ILE F 2 313 ? 96.503  139.604 144.497 1.00 55.14  ? 295 ILE E CB    1 
ATOM   12242 C CG1   . ILE F 2 313 ? 97.187  140.236 143.271 1.00 55.14  ? 295 ILE E CG1   1 
ATOM   12243 C CG2   . ILE F 2 313 ? 97.381  139.780 145.749 1.00 55.14  ? 295 ILE E CG2   1 
ATOM   12244 C CD1   . ILE F 2 313 ? 97.774  141.621 143.507 1.00 55.14  ? 295 ILE E CD1   1 
ATOM   12245 N N     . ASP F 2 314 ? 95.487  136.557 145.975 1.00 58.79  ? 296 ASP E N     1 
ATOM   12246 C CA    . ASP F 2 314 ? 94.489  135.785 146.711 1.00 58.79  ? 296 ASP E CA    1 
ATOM   12247 C C     . ASP F 2 314 ? 93.980  136.491 147.964 1.00 58.79  ? 296 ASP E C     1 
ATOM   12248 O O     . ASP F 2 314 ? 92.808  136.323 148.320 1.00 58.79  ? 296 ASP E O     1 
ATOM   12249 C CB    . ASP F 2 314 ? 95.078  134.424 147.091 1.00 58.79  ? 296 ASP E CB    1 
ATOM   12250 C CG    . ASP F 2 314 ? 94.014  133.369 147.360 1.00 58.79  ? 296 ASP E CG    1 
ATOM   12251 O OD1   . ASP F 2 314 ? 92.826  133.721 147.518 1.00 58.79  ? 296 ASP E OD1   1 
ATOM   12252 O OD2   . ASP F 2 314 ? 94.373  132.173 147.412 1.00 58.79  ? 296 ASP E OD2   1 
ATOM   12253 N N     . GLU F 2 315 ? 94.826  137.270 148.641 1.00 58.74  ? 297 GLU E N     1 
ATOM   12254 C CA    . GLU F 2 315 ? 94.566  137.819 149.976 1.00 58.74  ? 297 GLU E CA    1 
ATOM   12255 C C     . GLU F 2 315 ? 94.887  139.310 150.002 1.00 58.74  ? 297 GLU E C     1 
ATOM   12256 O O     . GLU F 2 315 ? 95.672  139.796 150.820 1.00 58.74  ? 297 GLU E O     1 
ATOM   12257 C CB    . GLU F 2 315 ? 95.342  137.055 151.052 1.00 58.74  ? 297 GLU E CB    1 
ATOM   12258 C CG    . GLU F 2 315 ? 95.400  135.541 150.822 1.00 58.74  ? 297 GLU E CG    1 
ATOM   12259 C CD    . GLU F 2 315 ? 95.873  134.749 152.035 1.00 58.74  ? 297 GLU E CD    1 
ATOM   12260 O OE1   . GLU F 2 315 ? 95.806  135.263 153.172 1.00 58.74  ? 297 GLU E OE1   1 
ATOM   12261 O OE2   . GLU F 2 315 ? 96.314  133.596 151.845 1.00 58.74  ? 297 GLU E OE2   1 
ATOM   12262 N N     . VAL F 2 316 ? 94.272  140.049 149.069 1.00 55.73  ? 298 VAL E N     1 
ATOM   12263 C CA    . VAL F 2 316 ? 94.596  141.456 148.817 1.00 55.73  ? 298 VAL E CA    1 
ATOM   12264 C C     . VAL F 2 316 ? 94.384  142.339 150.045 1.00 55.73  ? 298 VAL E C     1 
ATOM   12265 O O     . VAL F 2 316 ? 95.003  143.403 150.159 1.00 55.73  ? 298 VAL E O     1 
ATOM   12266 C CB    . VAL F 2 316 ? 93.769  141.962 147.615 1.00 55.73  ? 298 VAL E CB    1 
ATOM   12267 C CG1   . VAL F 2 316 ? 92.321  142.292 148.028 1.00 55.73  ? 298 VAL E CG1   1 
ATOM   12268 C CG2   . VAL F 2 316 ? 94.440  143.161 146.954 1.00 55.73  ? 298 VAL E CG2   1 
ATOM   12269 N N     . HIS F 2 317 ? 93.502  141.938 150.966 1.00 56.71  ? 299 HIS E N     1 
ATOM   12270 C CA    . HIS F 2 317 ? 93.351  142.680 152.215 1.00 56.71  ? 299 HIS E CA    1 
ATOM   12271 C C     . HIS F 2 317 ? 94.639  142.680 153.034 1.00 56.71  ? 299 HIS E C     1 
ATOM   12272 O O     . HIS F 2 317 ? 94.895  143.628 153.784 1.00 56.71  ? 299 HIS E O     1 
ATOM   12273 C CB    . HIS F 2 317 ? 92.204  142.095 153.041 1.00 56.71  ? 299 HIS E CB    1 
ATOM   12274 C CG    . HIS F 2 317 ? 92.442  140.689 153.495 1.00 56.71  ? 299 HIS E CG    1 
ATOM   12275 N ND1   . HIS F 2 317 ? 92.166  139.595 152.703 1.00 56.71  ? 299 HIS E ND1   1 
ATOM   12276 C CD2   . HIS F 2 317 ? 92.939  140.198 154.654 1.00 56.71  ? 299 HIS E CD2   1 
ATOM   12277 C CE1   . HIS F 2 317 ? 92.478  138.491 153.357 1.00 56.71  ? 299 HIS E CE1   1 
ATOM   12278 N NE2   . HIS F 2 317 ? 92.948  138.829 154.544 1.00 56.71  ? 299 HIS E NE2   1 
ATOM   12279 N N     . MET F 2 318 ? 95.461  141.635 152.901 1.00 62.20  ? 300 MET E N     1 
ATOM   12280 C CA    . MET F 2 318 ? 96.742  141.570 153.594 1.00 62.20  ? 300 MET E CA    1 
ATOM   12281 C C     . MET F 2 318 ? 97.807  142.473 152.978 1.00 62.20  ? 300 MET E C     1 
ATOM   12282 O O     . MET F 2 318 ? 98.888  142.599 153.563 1.00 62.20  ? 300 MET E O     1 
ATOM   12283 C CB    . MET F 2 318 ? 97.248  140.124 153.609 1.00 62.20  ? 300 MET E CB    1 
ATOM   12284 C CG    . MET F 2 318 ? 98.031  139.751 154.854 1.00 62.20  ? 300 MET E CG    1 
ATOM   12285 S SD    . MET F 2 318 ? 96.970  139.047 156.129 1.00 62.20  ? 300 MET E SD    1 
ATOM   12286 C CE    . MET F 2 318 ? 96.887  137.341 155.593 1.00 62.20  ? 300 MET E CE    1 
ATOM   12287 N N     . LEU F 2 319 ? 97.552  143.079 151.819 1.00 60.31  ? 301 LEU E N     1 
ATOM   12288 C CA    . LEU F 2 319 ? 98.513  143.999 151.225 1.00 60.31  ? 301 LEU E CA    1 
ATOM   12289 C C     . LEU F 2 319 ? 98.498  145.334 151.959 1.00 60.31  ? 301 LEU E C     1 
ATOM   12290 O O     . LEU F 2 319 ? 97.443  145.828 152.366 1.00 60.31  ? 301 LEU E O     1 
ATOM   12291 C CB    . LEU F 2 319 ? 98.192  144.213 149.744 1.00 60.31  ? 301 LEU E CB    1 
ATOM   12292 C CG    . LEU F 2 319 ? 98.379  143.067 148.742 1.00 60.31  ? 301 LEU E CG    1 
ATOM   12293 C CD1   . LEU F 2 319 ? 98.146  143.590 147.339 1.00 60.31  ? 301 LEU E CD1   1 
ATOM   12294 C CD2   . LEU F 2 319 ? 99.748  142.415 148.822 1.00 60.31  ? 301 LEU E CD2   1 
ATOM   12295 N N     . ASP F 2 320 ? 99.682  145.922 152.120 1.00 64.77  ? 302 ASP E N     1 
ATOM   12296 C CA    . ASP F 2 320 ? 99.820  147.202 152.796 1.00 64.77  ? 302 ASP E CA    1 
ATOM   12297 C C     . ASP F 2 320 ? 99.497  148.347 151.841 1.00 64.77  ? 302 ASP E C     1 
ATOM   12298 O O     . ASP F 2 320 ? 99.287  148.153 150.641 1.00 64.77  ? 302 ASP E O     1 
ATOM   12299 C CB    . ASP F 2 320 ? 101.234 147.369 153.348 1.00 64.77  ? 302 ASP E CB    1 
ATOM   12300 C CG    . ASP F 2 320 ? 101.699 146.164 154.135 1.00 64.77  ? 302 ASP E CG    1 
ATOM   12301 O OD1   . ASP F 2 320 ? 100.934 145.182 154.224 1.00 64.77  ? 302 ASP E OD1   1 
ATOM   12302 O OD2   . ASP F 2 320 ? 102.830 146.199 154.665 1.00 64.77  ? 302 ASP E OD2   1 
ATOM   12303 N N     . ILE F 2 321 ? 99.471  149.563 152.392 1.00 59.25  ? 303 ILE E N     1 
ATOM   12304 C CA    . ILE F 2 321 ? 99.184  150.737 151.574 1.00 59.25  ? 303 ILE E CA    1 
ATOM   12305 C C     . ILE F 2 321 ? 100.297 150.974 150.561 1.00 59.25  ? 303 ILE E C     1 
ATOM   12306 O O     . ILE F 2 321 ? 100.044 151.475 149.459 1.00 59.25  ? 303 ILE E O     1 
ATOM   12307 C CB    . ILE F 2 321 ? 98.923  151.967 152.482 1.00 59.25  ? 303 ILE E CB    1 
ATOM   12308 C CG1   . ILE F 2 321 ? 97.900  152.936 151.856 1.00 59.25  ? 303 ILE E CG1   1 
ATOM   12309 C CG2   . ILE F 2 321 ? 100.220 152.698 152.863 1.00 59.25  ? 303 ILE E CG2   1 
ATOM   12310 C CD1   . ILE F 2 321 ? 97.189  153.807 152.859 1.00 59.25  ? 303 ILE E CD1   1 
ATOM   12311 N N     . GLU F 2 322 ? 101.539 150.629 150.908 1.00 63.70  ? 304 GLU E N     1 
ATOM   12312 C CA    . GLU F 2 322 ? 102.624 150.720 149.940 1.00 63.70  ? 304 GLU E CA    1 
ATOM   12313 C C     . GLU F 2 322 ? 102.410 149.742 148.793 1.00 63.70  ? 304 GLU E C     1 
ATOM   12314 O O     . GLU F 2 322 ? 102.656 150.074 147.627 1.00 63.70  ? 304 GLU E O     1 
ATOM   12315 C CB    . GLU F 2 322 ? 103.961 150.467 150.635 1.00 63.70  ? 304 GLU E CB    1 
ATOM   12316 C CG    . GLU F 2 322 ? 104.348 151.569 151.628 1.00 63.70  ? 304 GLU E CG    1 
ATOM   12317 C CD    . GLU F 2 322 ? 104.802 151.050 152.986 1.00 63.70  ? 304 GLU E CD    1 
ATOM   12318 O OE1   . GLU F 2 322 ? 105.451 149.984 153.051 1.00 63.70  ? 304 GLU E OE1   1 
ATOM   12319 O OE2   . GLU F 2 322 ? 104.502 151.718 153.998 1.00 63.70  ? 304 GLU E OE2   1 
ATOM   12320 N N     . CYS F 2 323 ? 101.933 148.534 149.105 1.00 63.55  ? 305 CYS E N     1 
ATOM   12321 C CA    . CYS F 2 323 ? 101.637 147.555 148.065 1.00 63.55  ? 305 CYS E CA    1 
ATOM   12322 C C     . CYS F 2 323 ? 100.512 148.035 147.155 1.00 63.55  ? 305 CYS E C     1 
ATOM   12323 O O     . CYS F 2 323 ? 100.575 147.859 145.932 1.00 63.55  ? 305 CYS E O     1 
ATOM   12324 C CB    . CYS F 2 323 ? 101.270 146.219 148.704 1.00 63.55  ? 305 CYS E CB    1 
ATOM   12325 S SG    . CYS F 2 323 ? 102.604 145.427 149.617 1.00 63.55  ? 305 CYS E SG    1 
ATOM   12326 N N     . PHE F 2 324 ? 99.472  148.642 147.732 1.00 55.28  ? 306 PHE E N     1 
ATOM   12327 C CA    . PHE F 2 324 ? 98.380  149.163 146.916 1.00 55.28  ? 306 PHE E CA    1 
ATOM   12328 C C     . PHE F 2 324 ? 98.844  150.326 146.051 1.00 55.28  ? 306 PHE E C     1 
ATOM   12329 O O     . PHE F 2 324 ? 98.407  150.463 144.903 1.00 55.28  ? 306 PHE E O     1 
ATOM   12330 C CB    . PHE F 2 324 ? 97.213  149.596 147.802 1.00 55.28  ? 306 PHE E CB    1 
ATOM   12331 C CG    . PHE F 2 324 ? 96.366  148.459 148.297 1.00 55.28  ? 306 PHE E CG    1 
ATOM   12332 C CD1   . PHE F 2 324 ? 95.537  147.764 147.433 1.00 55.28  ? 306 PHE E CD1   1 
ATOM   12333 C CD2   . PHE F 2 324 ? 96.388  148.093 149.630 1.00 55.28  ? 306 PHE E CD2   1 
ATOM   12334 C CE1   . PHE F 2 324 ? 94.758  146.723 147.888 1.00 55.28  ? 306 PHE E CE1   1 
ATOM   12335 C CE2   . PHE F 2 324 ? 95.611  147.054 150.090 1.00 55.28  ? 306 PHE E CE2   1 
ATOM   12336 C CZ    . PHE F 2 324 ? 94.794  146.369 149.218 1.00 55.28  ? 306 PHE E CZ    1 
ATOM   12337 N N     . SER F 2 325 ? 99.719  151.181 146.589 1.00 58.24  ? 307 SER E N     1 
ATOM   12338 C CA    . SER F 2 325 ? 100.283 152.262 145.788 1.00 58.24  ? 307 SER E CA    1 
ATOM   12339 C C     . SER F 2 325 ? 101.102 151.711 144.630 1.00 58.24  ? 307 SER E C     1 
ATOM   12340 O O     . SER F 2 325 ? 101.036 152.230 143.508 1.00 58.24  ? 307 SER E O     1 
ATOM   12341 C CB    . SER F 2 325 ? 101.142 153.171 146.664 1.00 58.24  ? 307 SER E CB    1 
ATOM   12342 O OG    . SER F 2 325 ? 100.381 153.712 147.728 1.00 58.24  ? 307 SER E OG    1 
ATOM   12343 N N     . PHE F 2 326 ? 101.874 150.650 144.883 1.00 64.62  ? 308 PHE E N     1 
ATOM   12344 C CA    . PHE F 2 326 ? 102.639 150.024 143.811 1.00 64.62  ? 308 PHE E CA    1 
ATOM   12345 C C     . PHE F 2 326 ? 101.723 149.429 142.750 1.00 64.62  ? 308 PHE E C     1 
ATOM   12346 O O     . PHE F 2 326 ? 102.009 149.529 141.553 1.00 64.62  ? 308 PHE E O     1 
ATOM   12347 C CB    . PHE F 2 326 ? 103.562 148.942 144.366 1.00 64.62  ? 308 PHE E CB    1 
ATOM   12348 C CG    . PHE F 2 326 ? 104.277 148.173 143.297 1.00 64.62  ? 308 PHE E CG    1 
ATOM   12349 C CD1   . PHE F 2 326 ? 105.339 148.743 142.618 1.00 64.62  ? 308 PHE E CD1   1 
ATOM   12350 C CD2   . PHE F 2 326 ? 103.882 146.890 142.957 1.00 64.62  ? 308 PHE E CD2   1 
ATOM   12351 C CE1   . PHE F 2 326 ? 105.995 148.050 141.628 1.00 64.62  ? 308 PHE E CE1   1 
ATOM   12352 C CE2   . PHE F 2 326 ? 104.534 146.196 141.965 1.00 64.62  ? 308 PHE E CE2   1 
ATOM   12353 C CZ    . PHE F 2 326 ? 105.590 146.777 141.300 1.00 64.62  ? 308 PHE E CZ    1 
ATOM   12354 N N     . LEU F 2 327 ? 100.633 148.781 143.170 1.00 59.40  ? 309 LEU E N     1 
ATOM   12355 C CA    . LEU F 2 327 ? 99.696  148.210 142.205 1.00 59.40  ? 309 LEU E CA    1 
ATOM   12356 C C     . LEU F 2 327 ? 99.038  149.298 141.368 1.00 59.40  ? 309 LEU E C     1 
ATOM   12357 O O     . LEU F 2 327 ? 98.891  149.150 140.148 1.00 59.40  ? 309 LEU E O     1 
ATOM   12358 C CB    . LEU F 2 327 ? 98.627  147.387 142.924 1.00 59.40  ? 309 LEU E CB    1 
ATOM   12359 C CG    . LEU F 2 327 ? 99.030  146.049 143.547 1.00 59.40  ? 309 LEU E CG    1 
ATOM   12360 C CD1   . LEU F 2 327 ? 97.875  145.518 144.378 1.00 59.40  ? 309 LEU E CD1   1 
ATOM   12361 C CD2   . LEU F 2 327 ? 99.439  145.037 142.482 1.00 59.40  ? 309 LEU E CD2   1 
ATOM   12362 N N     . ASN F 2 328 ? 98.640  150.399 142.010 1.00 56.81  ? 310 ASN E N     1 
ATOM   12363 C CA    . ASN F 2 328 ? 98.026  151.506 141.286 1.00 56.81  ? 310 ASN E CA    1 
ATOM   12364 C C     . ASN F 2 328 ? 99.001  152.121 140.293 1.00 56.81  ? 310 ASN E C     1 
ATOM   12365 O O     . ASN F 2 328 ? 98.612  152.495 139.181 1.00 56.81  ? 310 ASN E O     1 
ATOM   12366 C CB    . ASN F 2 328 ? 97.528  152.558 142.274 1.00 56.81  ? 310 ASN E CB    1 
ATOM   12367 C CG    . ASN F 2 328 ? 96.763  153.675 141.600 1.00 56.81  ? 310 ASN E CG    1 
ATOM   12368 O OD1   . ASN F 2 328 ? 96.088  153.460 140.594 1.00 56.81  ? 310 ASN E OD1   1 
ATOM   12369 N ND2   . ASN F 2 328 ? 96.861  154.877 142.154 1.00 56.81  ? 310 ASN E ND2   1 
ATOM   12370 N N     . ARG F 2 329 ? 100.275 152.236 140.676 1.00 62.19  ? 311 ARG E N     1 
ATOM   12371 C CA    . ARG F 2 329 ? 101.277 152.743 139.744 1.00 62.19  ? 311 ARG E CA    1 
ATOM   12372 C C     . ARG F 2 329 ? 101.494 151.774 138.586 1.00 62.19  ? 311 ARG E C     1 
ATOM   12373 O O     . ARG F 2 329 ? 101.564 152.192 137.425 1.00 62.19  ? 311 ARG E O     1 
ATOM   12374 C CB    . ARG F 2 329 ? 102.590 153.002 140.488 1.00 62.19  ? 311 ARG E CB    1 
ATOM   12375 C CG    . ARG F 2 329 ? 103.654 153.775 139.702 1.00 62.19  ? 311 ARG E CG    1 
ATOM   12376 C CD    . ARG F 2 329 ? 105.023 153.619 140.337 1.00 62.19  ? 311 ARG E CD    1 
ATOM   12377 N NE    . ARG F 2 329 ? 105.025 154.014 141.742 1.00 62.19  ? 311 ARG E NE    1 
ATOM   12378 C CZ    . ARG F 2 329 ? 106.024 153.819 142.597 1.00 62.19  ? 311 ARG E CZ    1 
ATOM   12379 N NH1   . ARG F 2 329 ? 107.152 153.220 142.238 1.00 62.19  ? 311 ARG E NH1   1 
ATOM   12380 N NH2   . ARG F 2 329 ? 105.889 154.238 143.852 1.00 62.19  ? 311 ARG E NH2   1 
ATOM   12381 N N     . ALA F 2 330 ? 101.598 150.476 138.882 1.00 63.98  ? 312 ALA E N     1 
ATOM   12382 C CA    . ALA F 2 330 ? 101.955 149.505 137.854 1.00 63.98  ? 312 ALA E CA    1 
ATOM   12383 C C     . ALA F 2 330 ? 100.819 149.273 136.868 1.00 63.98  ? 312 ALA E C     1 
ATOM   12384 O O     . ALA F 2 330 ? 101.074 148.932 135.707 1.00 63.98  ? 312 ALA E O     1 
ATOM   12385 C CB    . ALA F 2 330 ? 102.368 148.186 138.504 1.00 63.98  ? 312 ALA E CB    1 
ATOM   12386 N N     . LEU F 2 331 ? 99.566  149.440 137.301 1.00 58.38  ? 313 LEU E N     1 
ATOM   12387 C CA    . LEU F 2 331 ? 98.446  149.290 136.375 1.00 58.38  ? 313 LEU E CA    1 
ATOM   12388 C C     . LEU F 2 331 ? 98.448  150.362 135.290 1.00 58.38  ? 313 LEU E C     1 
ATOM   12389 O O     . LEU F 2 331 ? 97.903  150.136 134.203 1.00 58.38  ? 313 LEU E O     1 
ATOM   12390 C CB    . LEU F 2 331 ? 97.124  149.330 137.139 1.00 58.38  ? 313 LEU E CB    1 
ATOM   12391 C CG    . LEU F 2 331 ? 96.778  148.099 137.984 1.00 58.38  ? 313 LEU E CG    1 
ATOM   12392 C CD1   . LEU F 2 331 ? 95.701  148.425 139.013 1.00 58.38  ? 313 LEU E CD1   1 
ATOM   12393 C CD2   . LEU F 2 331 ? 96.332  146.938 137.108 1.00 58.38  ? 313 LEU E CD2   1 
ATOM   12394 N N     . GLU F 2 332 ? 99.046  151.529 135.556 1.00 67.72  ? 314 GLU E N     1 
ATOM   12395 C CA    . GLU F 2 332 ? 99.076  152.606 134.570 1.00 67.72  ? 314 GLU E CA    1 
ATOM   12396 C C     . GLU F 2 332 ? 99.877  152.248 133.324 1.00 67.72  ? 314 GLU E C     1 
ATOM   12397 O O     . GLU F 2 332 ? 99.661  152.859 132.272 1.00 67.72  ? 314 GLU E O     1 
ATOM   12398 C CB    . GLU F 2 332 ? 99.657  153.875 135.196 1.00 67.72  ? 314 GLU E CB    1 
ATOM   12399 C CG    . GLU F 2 332 ? 98.805  154.468 136.304 1.00 67.72  ? 314 GLU E CG    1 
ATOM   12400 C CD    . GLU F 2 332 ? 99.438  155.693 136.936 1.00 67.72  ? 314 GLU E CD    1 
ATOM   12401 O OE1   . GLU F 2 332 ? 100.388 156.248 136.343 1.00 67.72  ? 314 GLU E OE1   1 
ATOM   12402 O OE2   . GLU F 2 332 ? 98.988  156.100 138.027 1.00 67.72  ? 314 GLU E OE2   1 
ATOM   12403 N N     . ASN F 2 333 ? 100.801 151.293 133.415 1.00 74.77  ? 315 ASN E N     1 
ATOM   12404 C CA    . ASN F 2 333 ? 101.568 150.884 132.247 1.00 74.77  ? 315 ASN E CA    1 
ATOM   12405 C C     . ASN F 2 333 ? 100.660 150.226 131.217 1.00 74.77  ? 315 ASN E C     1 
ATOM   12406 O O     . ASN F 2 333 ? 99.761  149.452 131.560 1.00 74.77  ? 315 ASN E O     1 
ATOM   12407 C CB    . ASN F 2 333 ? 102.679 149.912 132.645 1.00 74.77  ? 315 ASN E CB    1 
ATOM   12408 C CG    . ASN F 2 333 ? 103.591 150.469 133.720 1.00 74.77  ? 315 ASN E CG    1 
ATOM   12409 O OD1   . ASN F 2 333 ? 103.632 151.677 133.952 1.00 74.77  ? 315 ASN E OD1   1 
ATOM   12410 N ND2   . ASN F 2 333 ? 104.327 149.586 134.383 1.00 74.77  ? 315 ASN E ND2   1 
ATOM   12411 N N     . GLU F 2 334 ? 100.898 150.540 129.942 1.00 83.27  ? 316 GLU E N     1 
ATOM   12412 C CA    . GLU F 2 334 ? 100.188 149.865 128.860 1.00 83.27  ? 316 GLU E CA    1 
ATOM   12413 C C     . GLU F 2 334 ? 100.551 148.386 128.753 1.00 83.27  ? 316 GLU E C     1 
ATOM   12414 O O     . GLU F 2 334 ? 99.776  147.615 128.176 1.00 83.27  ? 316 GLU E O     1 
ATOM   12415 C CB    . GLU F 2 334 ? 100.453 150.593 127.530 1.00 83.27  ? 316 GLU E CB    1 
ATOM   12416 C CG    . GLU F 2 334 ? 101.769 150.274 126.777 1.00 83.27  ? 316 GLU E CG    1 
ATOM   12417 C CD    . GLU F 2 334 ? 103.034 150.541 127.583 1.00 83.27  ? 316 GLU E CD    1 
ATOM   12418 O OE1   . GLU F 2 334 ? 102.945 151.010 128.736 1.00 83.27  ? 316 GLU E OE1   1 
ATOM   12419 O OE2   . GLU F 2 334 ? 104.133 150.280 127.051 1.00 83.27  ? 316 GLU E OE2   1 
ATOM   12420 N N     . MET F 2 335 ? 101.700 147.974 129.291 1.00 79.51  ? 317 MET E N     1 
ATOM   12421 C CA    . MET F 2 335 ? 102.141 146.587 129.287 1.00 79.51  ? 317 MET E CA    1 
ATOM   12422 C C     . MET F 2 335 ? 101.605 145.782 130.471 1.00 79.51  ? 317 MET E C     1 
ATOM   12423 O O     . MET F 2 335 ? 102.113 144.688 130.734 1.00 79.51  ? 317 MET E O     1 
ATOM   12424 C CB    . MET F 2 335 ? 103.674 146.542 129.294 1.00 79.51  ? 317 MET E CB    1 
ATOM   12425 C CG    . MET F 2 335 ? 104.304 145.432 128.470 1.00 79.51  ? 317 MET E CG    1 
ATOM   12426 S SD    . MET F 2 335 ? 106.061 145.744 128.202 1.00 79.51  ? 317 MET E SD    1 
ATOM   12427 C CE    . MET F 2 335 ? 106.673 144.095 127.872 1.00 79.51  ? 317 MET E CE    1 
ATOM   12428 N N     . SER F 2 336 ? 100.596 146.286 131.184 1.00 70.20  ? 318 SER E N     1 
ATOM   12429 C CA    . SER F 2 336 ? 100.149 145.655 132.418 1.00 70.20  ? 318 SER E CA    1 
ATOM   12430 C C     . SER F 2 336 ? 99.279  144.431 132.123 1.00 70.20  ? 318 SER E C     1 
ATOM   12431 O O     . SER F 2 336 ? 98.677  144.338 131.050 1.00 70.20  ? 318 SER E O     1 
ATOM   12432 C CB    . SER F 2 336 ? 99.368  146.656 133.271 1.00 70.20  ? 318 SER E CB    1 
ATOM   12433 O OG    . SER F 2 336 ? 98.351  146.021 134.026 1.00 70.20  ? 318 SER E OG    1 
ATOM   12434 N N     . PRO F 2 337 ? 99.186  143.461 133.075 1.00 61.46  ? 319 PRO E N     1 
ATOM   12435 C CA    . PRO F 2 337 ? 98.262  142.338 132.887 1.00 61.46  ? 319 PRO E CA    1 
ATOM   12436 C C     . PRO F 2 337 ? 96.874  142.684 133.398 1.00 61.46  ? 319 PRO E C     1 
ATOM   12437 O O     . PRO F 2 337 ? 96.654  143.806 133.865 1.00 61.46  ? 319 PRO E O     1 
ATOM   12438 C CB    . PRO F 2 337 ? 98.916  141.230 133.715 1.00 61.46  ? 319 PRO E CB    1 
ATOM   12439 C CG    . PRO F 2 337 ? 99.439  141.967 134.881 1.00 61.46  ? 319 PRO E CG    1 
ATOM   12440 C CD    . PRO F 2 337 ? 99.881  143.327 134.369 1.00 61.46  ? 319 PRO E CD    1 
ATOM   12441 N N     . ILE F 2 338 ? 95.940  141.741 133.316 1.00 54.02  ? 320 ILE E N     1 
ATOM   12442 C CA    . ILE F 2 338 ? 94.613  141.913 133.900 1.00 54.02  ? 320 ILE E CA    1 
ATOM   12443 C C     . ILE F 2 338 ? 94.703  141.523 135.369 1.00 54.02  ? 320 ILE E C     1 
ATOM   12444 O O     . ILE F 2 338 ? 95.068  140.388 135.696 1.00 54.02  ? 320 ILE E O     1 
ATOM   12445 C CB    . ILE F 2 338 ? 93.560  141.066 133.166 1.00 54.02  ? 320 ILE E CB    1 
ATOM   12446 C CG1   . ILE F 2 338 ? 93.704  141.178 131.635 1.00 54.02  ? 320 ILE E CG1   1 
ATOM   12447 C CG2   . ILE F 2 338 ? 92.144  141.465 133.609 1.00 54.02  ? 320 ILE E CG2   1 
ATOM   12448 C CD1   . ILE F 2 338 ? 93.826  142.598 131.093 1.00 54.02  ? 320 ILE E CD1   1 
ATOM   12449 N N     . LEU F 2 339 ? 94.363  142.459 136.254 1.00 49.96  ? 321 LEU E N     1 
ATOM   12450 C CA    . LEU F 2 339 ? 94.483  142.259 137.693 1.00 49.96  ? 321 LEU E CA    1 
ATOM   12451 C C     . LEU F 2 339 ? 93.171  141.721 138.247 1.00 49.96  ? 321 LEU E C     1 
ATOM   12452 O O     . LEU F 2 339 ? 92.112  142.336 138.059 1.00 49.96  ? 321 LEU E O     1 
ATOM   12453 C CB    . LEU F 2 339 ? 94.862  143.566 138.392 1.00 49.96  ? 321 LEU E CB    1 
ATOM   12454 C CG    . LEU F 2 339 ? 94.904  143.591 139.929 1.00 49.96  ? 321 LEU E CG    1 
ATOM   12455 C CD1   . LEU F 2 339 ? 95.860  142.547 140.483 1.00 49.96  ? 321 LEU E CD1   1 
ATOM   12456 C CD2   . LEU F 2 339 ? 95.295  144.969 140.412 1.00 49.96  ? 321 LEU E CD2   1 
ATOM   12457 N N     . VAL F 2 340 ? 93.252  140.583 138.934 1.00 49.74  ? 322 VAL E N     1 
ATOM   12458 C CA    . VAL F 2 340 ? 92.161  140.020 139.719 1.00 49.74  ? 322 VAL E CA    1 
ATOM   12459 C C     . VAL F 2 340 ? 92.650  139.926 141.156 1.00 49.74  ? 322 VAL E C     1 
ATOM   12460 O O     . VAL F 2 340 ? 93.779  139.485 141.406 1.00 49.74  ? 322 VAL E O     1 
ATOM   12461 C CB    . VAL F 2 340 ? 91.724  138.644 139.184 1.00 49.74  ? 322 VAL E CB    1 
ATOM   12462 C CG1   . VAL F 2 340 ? 90.475  138.142 139.922 1.00 49.74  ? 322 VAL E CG1   1 
ATOM   12463 C CG2   . VAL F 2 340 ? 91.480  138.729 137.679 1.00 49.74  ? 322 VAL E CG2   1 
ATOM   12464 N N     . VAL F 2 341 ? 91.816  140.374 142.089 1.00 49.94  ? 323 VAL E N     1 
ATOM   12465 C CA    . VAL F 2 341 ? 92.100  140.317 143.516 1.00 49.94  ? 323 VAL E CA    1 
ATOM   12466 C C     . VAL F 2 341 ? 90.949  139.583 144.185 1.00 49.94  ? 323 VAL E C     1 
ATOM   12467 O O     . VAL F 2 341 ? 89.819  139.591 143.689 1.00 49.94  ? 323 VAL E O     1 
ATOM   12468 C CB    . VAL F 2 341 ? 92.318  141.729 144.121 1.00 49.94  ? 323 VAL E CB    1 
ATOM   12469 C CG1   . VAL F 2 341 ? 93.611  142.341 143.592 1.00 49.94  ? 323 VAL E CG1   1 
ATOM   12470 C CG2   . VAL F 2 341 ? 91.159  142.680 143.829 1.00 49.94  ? 323 VAL E CG2   1 
ATOM   12471 N N     . ALA F 2 342 ? 91.256  138.914 145.296 1.00 51.21  ? 324 ALA E N     1 
ATOM   12472 C CA    . ALA F 2 342 ? 90.296  138.110 146.037 1.00 51.21  ? 324 ALA E CA    1 
ATOM   12473 C C     . ALA F 2 342 ? 90.424  138.403 147.522 1.00 51.21  ? 324 ALA E C     1 
ATOM   12474 O O     . ALA F 2 342 ? 91.512  138.697 148.023 1.00 51.21  ? 324 ALA E O     1 
ATOM   12475 C CB    . ALA F 2 342 ? 90.503  136.616 145.780 1.00 51.21  ? 324 ALA E CB    1 
ATOM   12476 N N     . THR F 2 343 ? 89.295  138.331 148.219 1.00 53.15  ? 325 THR E N     1 
ATOM   12477 C CA    . THR F 2 343 ? 89.271  138.591 149.650 1.00 53.15  ? 325 THR E CA    1 
ATOM   12478 C C     . THR F 2 343 ? 87.998  138.000 150.234 1.00 53.15  ? 325 THR E C     1 
ATOM   12479 O O     . THR F 2 343 ? 87.033  137.728 149.516 1.00 53.15  ? 325 THR E O     1 
ATOM   12480 C CB    . THR F 2 343 ? 89.353  140.090 149.957 1.00 53.15  ? 325 THR E CB    1 
ATOM   12481 O OG1   . THR F 2 343 ? 89.561  140.279 151.361 1.00 53.15  ? 325 THR E OG1   1 
ATOM   12482 C CG2   . THR F 2 343 ? 88.075  140.815 149.536 1.00 53.15  ? 325 THR E CG2   1 
ATOM   12483 N N     . ASN F 2 344 ? 88.019  137.807 151.558 1.00 55.19  ? 326 ASN E N     1 
ATOM   12484 C CA    . ASN F 2 344 ? 86.865  137.343 152.323 1.00 55.19  ? 326 ASN E CA    1 
ATOM   12485 C C     . ASN F 2 344 ? 86.612  138.207 153.557 1.00 55.19  ? 326 ASN E C     1 
ATOM   12486 O O     . ASN F 2 344 ? 85.945  137.750 154.492 1.00 55.19  ? 326 ASN E O     1 
ATOM   12487 C CB    . ASN F 2 344 ? 87.055  135.878 152.728 1.00 55.19  ? 326 ASN E CB    1 
ATOM   12488 C CG    . ASN F 2 344 ? 88.296  135.662 153.568 1.00 55.19  ? 326 ASN E CG    1 
ATOM   12489 O OD1   . ASN F 2 344 ? 88.294  135.911 154.772 1.00 55.19  ? 326 ASN E OD1   1 
ATOM   12490 N ND2   . ASN F 2 344 ? 89.367  135.199 152.935 1.00 55.19  ? 326 ASN E ND2   1 
ATOM   12491 N N     . ARG F 2 345 ? 87.112  139.445 153.571 1.00 58.10  ? 327 ARG E N     1 
ATOM   12492 C CA    . ARG F 2 345 ? 86.966  140.369 154.687 1.00 58.10  ? 327 ARG E CA    1 
ATOM   12493 C C     . ARG F 2 345 ? 85.932  141.429 154.339 1.00 58.10  ? 327 ARG E C     1 
ATOM   12494 O O     . ARG F 2 345 ? 85.892  141.922 153.209 1.00 58.10  ? 327 ARG E O     1 
ATOM   12495 C CB    . ARG F 2 345 ? 88.300  141.047 155.007 1.00 58.10  ? 327 ARG E CB    1 
ATOM   12496 C CG    . ARG F 2 345 ? 89.371  140.126 155.577 1.00 58.10  ? 327 ARG E CG    1 
ATOM   12497 C CD    . ARG F 2 345 ? 89.076  139.672 157.001 1.00 58.10  ? 327 ARG E CD    1 
ATOM   12498 N NE    . ARG F 2 345 ? 90.312  139.492 157.764 1.00 58.10  ? 327 ARG E NE    1 
ATOM   12499 C CZ    . ARG F 2 345 ? 90.814  140.321 158.677 1.00 58.10  ? 327 ARG E CZ    1 
ATOM   12500 N NH1   . ARG F 2 345 ? 90.238  141.476 158.982 1.00 58.10  ? 327 ARG E NH1   1 
ATOM   12501 N NH2   . ARG F 2 345 ? 91.944  139.989 159.294 1.00 58.10  ? 327 ARG E NH2   1 
ATOM   12502 N N     . GLY F 2 346 ? 85.110  141.791 155.319 1.00 57.35  ? 328 GLY E N     1 
ATOM   12503 C CA    . GLY F 2 346 ? 84.162  142.872 155.140 1.00 57.35  ? 328 GLY E CA    1 
ATOM   12504 C C     . GLY F 2 346 ? 84.842  144.218 155.260 1.00 57.35  ? 328 GLY E C     1 
ATOM   12505 O O     . GLY F 2 346 ? 85.956  144.401 154.760 1.00 57.35  ? 328 GLY E O     1 
ATOM   12506 N N     . VAL F 2 347 ? 84.188  145.176 155.914 1.00 54.37  ? 329 VAL E N     1 
ATOM   12507 C CA    . VAL F 2 347 ? 84.833  146.454 156.186 1.00 54.37  ? 329 VAL E CA    1 
ATOM   12508 C C     . VAL F 2 347 ? 85.961  146.229 157.184 1.00 54.37  ? 329 VAL E C     1 
ATOM   12509 O O     . VAL F 2 347 ? 85.809  145.484 158.161 1.00 54.37  ? 329 VAL E O     1 
ATOM   12510 C CB    . VAL F 2 347 ? 83.802  147.482 156.686 1.00 54.37  ? 329 VAL E CB    1 
ATOM   12511 C CG1   . VAL F 2 347 ? 83.364  147.193 158.129 1.00 54.37  ? 329 VAL E CG1   1 
ATOM   12512 C CG2   . VAL F 2 347 ? 84.332  148.913 156.536 1.00 54.37  ? 329 VAL E CG2   1 
ATOM   12513 N N     . THR F 2 348 ? 87.117  146.830 156.918 1.00 57.53  ? 330 THR E N     1 
ATOM   12514 C CA    . THR F 2 348 ? 88.274  146.639 157.783 1.00 57.53  ? 330 THR E CA    1 
ATOM   12515 C C     . THR F 2 348 ? 89.264  147.765 157.533 1.00 57.53  ? 330 THR E C     1 
ATOM   12516 O O     . THR F 2 348 ? 89.093  148.582 156.627 1.00 57.53  ? 330 THR E O     1 
ATOM   12517 C CB    . THR F 2 348 ? 88.938  145.269 157.565 1.00 57.53  ? 330 THR E CB    1 
ATOM   12518 O OG1   . THR F 2 348 ? 90.181  145.224 158.277 1.00 57.53  ? 330 THR E OG1   1 
ATOM   12519 C CG2   . THR F 2 348 ? 89.211  144.984 156.088 1.00 57.53  ? 330 THR E CG2   1 
ATOM   12520 N N     . THR F 2 349 ? 90.307  147.792 158.359 1.00 60.00  ? 331 THR E N     1 
ATOM   12521 C CA    . THR F 2 349 ? 91.336  148.820 158.299 1.00 60.00  ? 331 THR E CA    1 
ATOM   12522 C C     . THR F 2 349 ? 92.487  148.341 157.425 1.00 60.00  ? 331 THR E C     1 
ATOM   12523 O O     . THR F 2 349 ? 92.936  147.198 157.554 1.00 60.00  ? 331 THR E O     1 
ATOM   12524 C CB    . THR F 2 349 ? 91.836  149.149 159.705 1.00 60.00  ? 331 THR E CB    1 
ATOM   12525 O OG1   . THR F 2 349 ? 90.737  149.110 160.624 1.00 60.00  ? 331 THR E OG1   1 
ATOM   12526 C CG2   . THR F 2 349 ? 92.456  150.533 159.743 1.00 60.00  ? 331 THR E CG2   1 
ATOM   12527 N N     . ILE F 2 350 ? 92.964  149.218 156.540 1.00 58.36  ? 332 ILE E N     1 
ATOM   12528 C CA    . ILE F 2 350 ? 94.068  148.852 155.659 1.00 58.36  ? 332 ILE E CA    1 
ATOM   12529 C C     . ILE F 2 350 ? 95.330  148.719 156.499 1.00 58.36  ? 332 ILE E C     1 
ATOM   12530 O O     . ILE F 2 350 ? 95.557  149.489 157.442 1.00 58.36  ? 332 ILE E O     1 
ATOM   12531 C CB    . ILE F 2 350 ? 94.264  149.874 154.518 1.00 58.36  ? 332 ILE E CB    1 
ATOM   12532 C CG1   . ILE F 2 350 ? 92.931  150.261 153.846 1.00 58.36  ? 332 ILE E CG1   1 
ATOM   12533 C CG2   . ILE F 2 350 ? 95.199  149.318 153.430 1.00 58.36  ? 332 ILE E CG2   1 
ATOM   12534 C CD1   . ILE F 2 350 ? 92.346  151.590 154.297 1.00 58.36  ? 332 ILE E CD1   1 
ATOM   12535 N N     . ARG F 2 351 ? 96.149  147.724 156.172 1.00 64.43  ? 333 ARG E N     1 
ATOM   12536 C CA    . ARG F 2 351 ? 97.399  147.518 156.890 1.00 64.43  ? 333 ARG E CA    1 
ATOM   12537 C C     . ARG F 2 351 ? 98.340  148.693 156.665 1.00 64.43  ? 333 ARG E C     1 
ATOM   12538 O O     . ARG F 2 351 ? 98.477  149.198 155.547 1.00 64.43  ? 333 ARG E O     1 
ATOM   12539 C CB    . ARG F 2 351 ? 98.059  146.218 156.439 1.00 64.43  ? 333 ARG E CB    1 
ATOM   12540 C CG    . ARG F 2 351 ? 97.392  144.968 156.990 1.00 64.43  ? 333 ARG E CG    1 
ATOM   12541 C CD    . ARG F 2 351 ? 98.220  143.730 156.703 1.00 64.43  ? 333 ARG E CD    1 
ATOM   12542 N NE    . ARG F 2 351 ? 99.432  143.688 157.521 1.00 64.43  ? 333 ARG E NE    1 
ATOM   12543 C CZ    . ARG F 2 351 ? 100.631 143.250 157.143 1.00 64.43  ? 333 ARG E CZ    1 
ATOM   12544 N NH1   . ARG F 2 351 ? 100.845 142.703 155.954 1.00 64.43  ? 333 ARG E NH1   1 
ATOM   12545 N NH2   . ARG F 2 351 ? 101.649 143.348 157.993 1.00 64.43  ? 333 ARG E NH2   1 
ATOM   12546 N N     . GLY F 2 352 ? 98.989  149.127 157.743 1.00 65.64  ? 334 GLY E N     1 
ATOM   12547 C CA    . GLY F 2 352 ? 99.816  150.315 157.710 1.00 65.64  ? 334 GLY E CA    1 
ATOM   12548 C C     . GLY F 2 352 ? 99.067  151.624 157.818 1.00 65.64  ? 334 GLY E C     1 
ATOM   12549 O O     . GLY F 2 352 ? 99.684  152.680 157.637 1.00 65.64  ? 334 GLY E O     1 
ATOM   12550 N N     . THR F 2 353 ? 97.760  151.595 158.092 1.00 61.96  ? 335 THR E N     1 
ATOM   12551 C CA    . THR F 2 353 ? 96.958  152.804 158.224 1.00 61.96  ? 335 THR E CA    1 
ATOM   12552 C C     . THR F 2 353 ? 95.833  152.531 159.211 1.00 61.96  ? 335 THR E C     1 
ATOM   12553 O O     . THR F 2 353 ? 95.445  151.382 159.437 1.00 61.96  ? 335 THR E O     1 
ATOM   12554 C CB    . THR F 2 353 ? 96.380  153.264 156.874 1.00 61.96  ? 335 THR E CB    1 
ATOM   12555 O OG1   . THR F 2 353 ? 97.340  153.047 155.836 1.00 61.96  ? 335 THR E OG1   1 
ATOM   12556 C CG2   . THR F 2 353 ? 96.014  154.750 156.897 1.00 61.96  ? 335 THR E CG2   1 
ATOM   12557 N N     . ASN F 2 354 ? 95.322  153.611 159.802 1.00 64.25  ? 336 ASN E N     1 
ATOM   12558 C CA    . ASN F 2 354 ? 94.216  153.558 160.749 1.00 64.25  ? 336 ASN E CA    1 
ATOM   12559 C C     . ASN F 2 354 ? 92.853  153.824 160.114 1.00 64.25  ? 336 ASN E C     1 
ATOM   12560 O O     . ASN F 2 354 ? 91.854  153.856 160.839 1.00 64.25  ? 336 ASN E O     1 
ATOM   12561 C CB    . ASN F 2 354 ? 94.447  154.567 161.877 1.00 64.25  ? 336 ASN E CB    1 
ATOM   12562 C CG    . ASN F 2 354 ? 94.026  155.976 161.497 1.00 64.25  ? 336 ASN E CG    1 
ATOM   12563 O OD1   . ASN F 2 354 ? 94.347  156.463 160.411 1.00 64.25  ? 336 ASN E OD1   1 
ATOM   12564 N ND2   . ASN F 2 354 ? 93.296  156.637 162.391 1.00 64.25  ? 336 ASN E ND2   1 
ATOM   12565 N N     . GLN F 2 355 ? 92.778  154.008 158.793 1.00 62.94  ? 337 GLN E N     1 
ATOM   12566 C CA    . GLN F 2 355 ? 91.526  154.318 158.115 1.00 62.94  ? 337 GLN E CA    1 
ATOM   12567 C C     . GLN F 2 355 ? 90.786  153.035 157.767 1.00 62.94  ? 337 GLN E C     1 
ATOM   12568 O O     . GLN F 2 355 ? 91.392  152.059 157.320 1.00 62.94  ? 337 GLN E O     1 
ATOM   12569 C CB    . GLN F 2 355 ? 91.791  155.123 156.839 1.00 62.94  ? 337 GLN E CB    1 
ATOM   12570 C CG    . GLN F 2 355 ? 92.256  156.564 157.055 1.00 62.94  ? 337 GLN E CG    1 
ATOM   12571 C CD    . GLN F 2 355 ? 91.210  157.438 157.730 1.00 62.94  ? 337 GLN E CD    1 
ATOM   12572 O OE1   . GLN F 2 355 ? 90.104  157.604 157.217 1.00 62.94  ? 337 GLN E OE1   1 
ATOM   12573 N NE2   . GLN F 2 355 ? 91.553  157.995 158.887 1.00 62.94  ? 337 GLN E NE2   1 
ATOM   12574 N N     . LYS F 2 356 ? 89.472  153.047 157.980 1.00 58.76  ? 338 LYS E N     1 
ATOM   12575 C CA    . LYS F 2 356 ? 88.605  151.912 157.694 1.00 58.76  ? 338 LYS E CA    1 
ATOM   12576 C C     . LYS F 2 356 ? 87.980  152.084 156.317 1.00 58.76  ? 338 LYS E C     1 
ATOM   12577 O O     . LYS F 2 356 ? 87.567  153.189 155.949 1.00 58.76  ? 338 LYS E O     1 
ATOM   12578 C CB    . LYS F 2 356 ? 87.515  151.789 158.759 1.00 58.76  ? 338 LYS E CB    1 
ATOM   12579 C CG    . LYS F 2 356 ? 86.821  150.435 158.784 1.00 58.76  ? 338 LYS E CG    1 
ATOM   12580 C CD    . LYS F 2 356 ? 85.664  150.391 159.778 1.00 58.76  ? 338 LYS E CD    1 
ATOM   12581 C CE    . LYS F 2 356 ? 86.140  150.189 161.210 1.00 58.76  ? 338 LYS E CE    1 
ATOM   12582 N NZ    . LYS F 2 356 ? 86.586  148.792 161.462 1.00 58.76  ? 338 LYS E NZ    1 
ATOM   12583 N N     . SER F 2 357 ? 87.927  150.995 155.556 1.00 54.36  ? 339 SER E N     1 
ATOM   12584 C CA    . SER F 2 357 ? 87.344  151.004 154.221 1.00 54.36  ? 339 SER E CA    1 
ATOM   12585 C C     . SER F 2 357 ? 86.848  149.603 153.906 1.00 54.36  ? 339 SER E C     1 
ATOM   12586 O O     . SER F 2 357 ? 87.164  148.646 154.627 1.00 54.36  ? 339 SER E O     1 
ATOM   12587 C CB    . SER F 2 357 ? 88.359  151.463 153.170 1.00 54.36  ? 339 SER E CB    1 
ATOM   12588 O OG    . SER F 2 357 ? 89.154  150.375 152.731 1.00 54.36  ? 339 SER E OG    1 
ATOM   12589 N N     . PRO F 2 358 ? 86.057  149.441 152.838 1.00 52.03  ? 340 PRO E N     1 
ATOM   12590 C CA    . PRO F 2 358 ? 85.640  148.087 152.438 1.00 52.03  ? 340 PRO E CA    1 
ATOM   12591 C C     . PRO F 2 358 ? 86.823  147.243 151.984 1.00 52.03  ? 340 PRO E C     1 
ATOM   12592 O O     . PRO F 2 358 ? 87.640  147.680 151.173 1.00 52.03  ? 340 PRO E O     1 
ATOM   12593 C CB    . PRO F 2 358 ? 84.663  148.342 151.285 1.00 52.03  ? 340 PRO E CB    1 
ATOM   12594 C CG    . PRO F 2 358 ? 84.179  149.710 151.496 1.00 52.03  ? 340 PRO E CG    1 
ATOM   12595 C CD    . PRO F 2 358 ? 85.343  150.461 152.046 1.00 52.03  ? 340 PRO E CD    1 
ATOM   12596 N N     . HIS F 2 359 ? 86.912  146.029 152.525 1.00 52.93  ? 341 HIS E N     1 
ATOM   12597 C CA    . HIS F 2 359 ? 87.867  144.997 152.123 1.00 52.93  ? 341 HIS E CA    1 
ATOM   12598 C C     . HIS F 2 359 ? 89.326  145.359 152.380 1.00 52.93  ? 341 HIS E C     1 
ATOM   12599 O O     . HIS F 2 359 ? 90.217  144.651 151.895 1.00 52.93  ? 341 HIS E O     1 
ATOM   12600 C CB    . HIS F 2 359 ? 87.713  144.638 150.640 1.00 52.93  ? 341 HIS E CB    1 
ATOM   12601 C CG    . HIS F 2 359 ? 86.311  144.308 150.240 1.00 52.93  ? 341 HIS E CG    1 
ATOM   12602 N ND1   . HIS F 2 359 ? 85.481  145.215 149.618 1.00 52.93  ? 341 HIS E ND1   1 
ATOM   12603 C CD2   . HIS F 2 359 ? 85.591  143.169 150.373 1.00 52.93  ? 341 HIS E CD2   1 
ATOM   12604 C CE1   . HIS F 2 359 ? 84.311  144.649 149.384 1.00 52.93  ? 341 HIS E CE1   1 
ATOM   12605 N NE2   . HIS F 2 359 ? 84.351  143.408 149.834 1.00 52.93  ? 341 HIS E NE2   1 
ATOM   12606 N N     . GLY F 2 360 ? 89.607  146.418 153.134 1.00 52.90  ? 342 GLY E N     1 
ATOM   12607 C CA    . GLY F 2 360 ? 90.983  146.828 153.346 1.00 52.90  ? 342 GLY E CA    1 
ATOM   12608 C C     . GLY F 2 360 ? 91.687  147.264 152.082 1.00 52.90  ? 342 GLY E C     1 
ATOM   12609 O O     . GLY F 2 360 ? 92.891  147.022 151.939 1.00 52.90  ? 342 GLY E O     1 
ATOM   12610 N N     . ILE F 2 361 ? 90.961  147.899 151.164 1.00 50.74  ? 343 ILE E N     1 
ATOM   12611 C CA    . ILE F 2 361 ? 91.469  148.370 149.875 1.00 50.74  ? 343 ILE E CA    1 
ATOM   12612 C C     . ILE F 2 361 ? 91.291  149.888 149.893 1.00 50.74  ? 343 ILE E C     1 
ATOM   12613 O O     . ILE F 2 361 ? 90.291  150.357 150.455 1.00 50.74  ? 343 ILE E O     1 
ATOM   12614 C CB    . ILE F 2 361 ? 90.724  147.714 148.694 1.00 50.74  ? 343 ILE E CB    1 
ATOM   12615 C CG1   . ILE F 2 361 ? 90.909  146.182 148.696 1.00 50.74  ? 343 ILE E CG1   1 
ATOM   12616 C CG2   . ILE F 2 361 ? 91.220  148.303 147.362 1.00 50.74  ? 343 ILE E CG2   1 
ATOM   12617 C CD1   . ILE F 2 361 ? 89.954  145.419 147.786 1.00 50.74  ? 343 ILE E CD1   1 
ATOM   12618 N N     . PRO F 2 362 ? 92.190  150.702 149.331 1.00 50.69  ? 344 PRO E N     1 
ATOM   12619 C CA    . PRO F 2 362 ? 91.906  152.140 149.260 1.00 50.69  ? 344 PRO E CA    1 
ATOM   12620 C C     . PRO F 2 362 ? 90.739  152.438 148.333 1.00 50.69  ? 344 PRO E C     1 
ATOM   12621 O O     . PRO F 2 362 ? 90.418  151.674 147.422 1.00 50.69  ? 344 PRO E O     1 
ATOM   12622 C CB    . PRO F 2 362 ? 93.208  152.741 148.724 1.00 50.69  ? 344 PRO E CB    1 
ATOM   12623 C CG    . PRO F 2 362 ? 94.242  151.761 149.059 1.00 50.69  ? 344 PRO E CG    1 
ATOM   12624 C CD    . PRO F 2 362 ? 93.582  150.436 148.916 1.00 50.69  ? 344 PRO E CD    1 
ATOM   12625 N N     . ILE F 2 363 ? 90.096  153.579 148.591 1.00 47.95  ? 345 ILE E N     1 
ATOM   12626 C CA    . ILE F 2 363 ? 88.899  153.955 147.844 1.00 47.95  ? 345 ILE E CA    1 
ATOM   12627 C C     . ILE F 2 363 ? 89.231  154.212 146.379 1.00 47.95  ? 345 ILE E C     1 
ATOM   12628 O O     . ILE F 2 363 ? 88.409  153.937 145.494 1.00 47.95  ? 345 ILE E O     1 
ATOM   12629 C CB    . ILE F 2 363 ? 88.227  155.176 148.511 1.00 47.95  ? 345 ILE E CB    1 
ATOM   12630 C CG1   . ILE F 2 363 ? 87.553  154.767 149.832 1.00 47.95  ? 345 ILE E CG1   1 
ATOM   12631 C CG2   . ILE F 2 363 ? 87.203  155.861 147.581 1.00 47.95  ? 345 ILE E CG2   1 
ATOM   12632 C CD1   . ILE F 2 363 ? 86.197  154.075 149.687 1.00 47.95  ? 345 ILE E CD1   1 
ATOM   12633 N N     . ASP F 2 364 ? 90.422  154.745 146.092 1.00 49.14  ? 346 ASP E N     1 
ATOM   12634 C CA    . ASP F 2 364 ? 90.791  155.039 144.712 1.00 49.14  ? 346 ASP E CA    1 
ATOM   12635 C C     . ASP F 2 364 ? 90.918  153.783 143.859 1.00 49.14  ? 346 ASP E C     1 
ATOM   12636 O O     . ASP F 2 364 ? 90.756  153.870 142.637 1.00 49.14  ? 346 ASP E O     1 
ATOM   12637 C CB    . ASP F 2 364 ? 92.099  155.833 144.669 1.00 49.14  ? 346 ASP E CB    1 
ATOM   12638 C CG    . ASP F 2 364 ? 93.327  154.952 144.772 1.00 49.14  ? 346 ASP E CG    1 
ATOM   12639 O OD1   . ASP F 2 364 ? 93.646  154.498 145.889 1.00 49.14  ? 346 ASP E OD1   1 
ATOM   12640 O OD2   . ASP F 2 364 ? 93.978  154.717 143.732 1.00 49.14  ? 346 ASP E OD2   1 
ATOM   12641 N N     . LEU F 2 365 ? 91.204  152.628 144.470 1.00 48.49  ? 347 LEU E N     1 
ATOM   12642 C CA    . LEU F 2 365 ? 91.187  151.349 143.770 1.00 48.49  ? 347 LEU E CA    1 
ATOM   12643 C C     . LEU F 2 365 ? 89.808  150.706 143.784 1.00 48.49  ? 347 LEU E C     1 
ATOM   12644 O O     . LEU F 2 365 ? 89.434  150.047 142.809 1.00 48.49  ? 347 LEU E O     1 
ATOM   12645 C CB    . LEU F 2 365 ? 92.208  150.391 144.394 1.00 48.49  ? 347 LEU E CB    1 
ATOM   12646 C CG    . LEU F 2 365 ? 92.512  149.067 143.677 1.00 48.49  ? 347 LEU E CG    1 
ATOM   12647 C CD1   . LEU F 2 365 ? 93.210  149.287 142.334 1.00 48.49  ? 347 LEU E CD1   1 
ATOM   12648 C CD2   . LEU F 2 365 ? 93.347  148.170 144.587 1.00 48.49  ? 347 LEU E CD2   1 
ATOM   12649 N N     . LEU F 2 366 ? 89.044  150.886 144.866 1.00 48.03  ? 348 LEU E N     1 
ATOM   12650 C CA    . LEU F 2 366 ? 87.694  150.335 144.922 1.00 48.03  ? 348 LEU E CA    1 
ATOM   12651 C C     . LEU F 2 366 ? 86.781  150.975 143.889 1.00 48.03  ? 348 LEU E C     1 
ATOM   12652 O O     . LEU F 2 366 ? 85.857  150.321 143.393 1.00 48.03  ? 348 LEU E O     1 
ATOM   12653 C CB    . LEU F 2 366 ? 87.098  150.527 146.315 1.00 48.03  ? 348 LEU E CB    1 
ATOM   12654 C CG    . LEU F 2 366 ? 87.589  149.648 147.464 1.00 48.03  ? 348 LEU E CG    1 
ATOM   12655 C CD1   . LEU F 2 366 ? 86.940  150.115 148.755 1.00 48.03  ? 348 LEU E CD1   1 
ATOM   12656 C CD2   . LEU F 2 366 ? 87.296  148.173 147.225 1.00 48.03  ? 348 LEU E CD2   1 
ATOM   12657 N N     . ASP F 2 367 ? 87.062  152.221 143.512 1.00 45.63  ? 349 ASP E N     1 
ATOM   12658 C CA    . ASP F 2 367 ? 86.216  152.956 142.534 1.00 45.63  ? 349 ASP E CA    1 
ATOM   12659 C C     . ASP F 2 367 ? 86.417  152.376 141.136 1.00 45.63  ? 349 ASP E C     1 
ATOM   12660 O O     . ASP F 2 367 ? 85.553  152.654 140.285 1.00 45.63  ? 349 ASP E O     1 
ATOM   12661 C CB    . ASP F 2 367 ? 86.513  154.443 142.546 1.00 45.63  ? 349 ASP E CB    1 
ATOM   12662 C CG    . ASP F 2 367 ? 85.975  155.208 143.746 1.00 45.63  ? 349 ASP E CG    1 
ATOM   12663 O OD1   . ASP F 2 367 ? 84.758  155.114 144.004 1.00 45.63  ? 349 ASP E OD1   1 
ATOM   12664 O OD2   . ASP F 2 367 ? 86.771  155.915 144.395 1.00 45.63  ? 349 ASP E OD2   1 
ATOM   12665 N N     . ARG F 2 368 ? 87.495  151.626 140.893 1.00 47.25  ? 350 ARG E N     1 
ATOM   12666 C CA    . ARG F 2 368 ? 87.764  150.986 139.611 1.00 47.25  ? 350 ARG E CA    1 
ATOM   12667 C C     . ARG F 2 368 ? 87.463  149.492 139.595 1.00 47.25  ? 350 ARG E C     1 
ATOM   12668 O O     . ARG F 2 368 ? 87.291  148.928 138.509 1.00 47.25  ? 350 ARG E O     1 
ATOM   12669 C CB    . ARG F 2 368 ? 89.232  151.194 139.224 1.00 47.25  ? 350 ARG E CB    1 
ATOM   12670 C CG    . ARG F 2 368 ? 89.560  152.622 138.817 1.00 47.25  ? 350 ARG E CG    1 
ATOM   12671 C CD    . ARG F 2 368 ? 90.969  153.018 139.224 1.00 47.25  ? 350 ARG E CD    1 
ATOM   12672 N NE    . ARG F 2 368 ? 91.976  152.140 138.633 1.00 47.25  ? 350 ARG E NE    1 
ATOM   12673 C CZ    . ARG F 2 368 ? 93.225  151.992 139.061 1.00 47.25  ? 350 ARG E CZ    1 
ATOM   12674 N NH1   . ARG F 2 368 ? 93.696  152.656 140.109 1.00 47.25  ? 350 ARG E NH1   1 
ATOM   12675 N NH2   . ARG F 2 368 ? 94.033  151.158 138.414 1.00 47.25  ? 350 ARG E NH2   1 
ATOM   12676 N N     . LEU F 2 369 ? 87.392  148.838 140.753 1.00 44.41  ? 351 LEU E N     1 
ATOM   12677 C CA    . LEU F 2 369 ? 87.236  147.389 140.787 1.00 44.41  ? 351 LEU E CA    1 
ATOM   12678 C C     . LEU F 2 369 ? 85.813  146.983 140.423 1.00 44.41  ? 351 LEU E C     1 
ATOM   12679 O O     . LEU F 2 369 ? 84.843  147.543 140.942 1.00 44.41  ? 351 LEU E O     1 
ATOM   12680 C CB    . LEU F 2 369 ? 87.586  146.850 142.174 1.00 44.41  ? 351 LEU E CB    1 
ATOM   12681 C CG    . LEU F 2 369 ? 89.062  146.745 142.563 1.00 44.41  ? 351 LEU E CG    1 
ATOM   12682 C CD1   . LEU F 2 369 ? 89.183  146.611 144.067 1.00 44.41  ? 351 LEU E CD1   1 
ATOM   12683 C CD2   . LEU F 2 369 ? 89.747  145.572 141.890 1.00 44.41  ? 351 LEU E CD2   1 
ATOM   12684 N N     . LEU F 2 370 ? 85.696  146.000 139.529 1.00 44.49  ? 352 LEU E N     1 
ATOM   12685 C CA    . LEU F 2 370 ? 84.432  145.323 139.251 1.00 44.49  ? 352 LEU E CA    1 
ATOM   12686 C C     . LEU F 2 370 ? 84.304  144.167 140.235 1.00 44.49  ? 352 LEU E C     1 
ATOM   12687 O O     . LEU F 2 370 ? 85.089  143.215 140.187 1.00 44.49  ? 352 LEU E O     1 
ATOM   12688 C CB    . LEU F 2 370 ? 84.386  144.827 137.809 1.00 44.49  ? 352 LEU E CB    1 
ATOM   12689 C CG    . LEU F 2 370 ? 84.274  145.906 136.732 1.00 44.49  ? 352 LEU E CG    1 
ATOM   12690 C CD1   . LEU F 2 370 ? 84.718  145.356 135.390 1.00 44.49  ? 352 LEU E CD1   1 
ATOM   12691 C CD2   . LEU F 2 370 ? 82.856  146.445 136.642 1.00 44.49  ? 352 LEU E CD2   1 
ATOM   12692 N N     . ILE F 2 371 ? 83.313  144.245 141.116 1.00 45.48  ? 353 ILE E N     1 
ATOM   12693 C CA    . ILE F 2 371 ? 83.230  143.390 142.295 1.00 45.48  ? 353 ILE E CA    1 
ATOM   12694 C C     . ILE F 2 371 ? 82.313  142.222 141.947 1.00 45.48  ? 353 ILE E C     1 
ATOM   12695 O O     . ILE F 2 371 ? 81.089  142.368 141.898 1.00 45.48  ? 353 ILE E O     1 
ATOM   12696 C CB    . ILE F 2 371 ? 82.732  144.164 143.522 1.00 45.48  ? 353 ILE E CB    1 
ATOM   12697 C CG1   . ILE F 2 371 ? 83.418  145.541 143.591 1.00 45.48  ? 353 ILE E CG1   1 
ATOM   12698 C CG2   . ILE F 2 371 ? 82.992  143.359 144.812 1.00 45.48  ? 353 ILE E CG2   1 
ATOM   12699 C CD1   . ILE F 2 371 ? 83.327  146.261 144.929 1.00 45.48  ? 353 ILE E CD1   1 
ATOM   12700 N N     . ILE F 2 372 ? 82.911  141.059 141.708 1.00 48.56  ? 354 ILE E N     1 
ATOM   12701 C CA    . ILE F 2 372 ? 82.174  139.800 141.672 1.00 48.56  ? 354 ILE E CA    1 
ATOM   12702 C C     . ILE F 2 372 ? 81.956  139.339 143.105 1.00 48.56  ? 354 ILE E C     1 
ATOM   12703 O O     . ILE F 2 372 ? 82.841  139.483 143.957 1.00 48.56  ? 354 ILE E O     1 
ATOM   12704 C CB    . ILE F 2 372 ? 82.936  138.735 140.856 1.00 48.56  ? 354 ILE E CB    1 
ATOM   12705 C CG1   . ILE F 2 372 ? 82.986  139.096 139.368 1.00 48.56  ? 354 ILE E CG1   1 
ATOM   12706 C CG2   . ILE F 2 372 ? 82.291  137.351 141.022 1.00 48.56  ? 354 ILE E CG2   1 
ATOM   12707 C CD1   . ILE F 2 372 ? 84.144  138.456 138.628 1.00 48.56  ? 354 ILE E CD1   1 
ATOM   12708 N N     . THR F 2 373 ? 80.769  138.800 143.377 1.00 50.95  ? 355 THR E N     1 
ATOM   12709 C CA    . THR F 2 373 ? 80.459  138.117 144.626 1.00 50.95  ? 355 THR E CA    1 
ATOM   12710 C C     . THR F 2 373 ? 80.028  136.692 144.307 1.00 50.95  ? 355 THR E C     1 
ATOM   12711 O O     . THR F 2 373 ? 79.276  136.461 143.354 1.00 50.95  ? 355 THR E O     1 
ATOM   12712 C CB    . THR F 2 373 ? 79.370  138.866 145.422 1.00 50.95  ? 355 THR E CB    1 
ATOM   12713 O OG1   . THR F 2 373 ? 79.293  138.333 146.750 1.00 50.95  ? 355 THR E OG1   1 
ATOM   12714 C CG2   . THR F 2 373 ? 77.999  138.768 144.753 1.00 50.95  ? 355 THR E CG2   1 
ATOM   12715 N N     . THR F 2 374 ? 80.543  135.741 145.087 1.00 50.72  ? 356 THR E N     1 
ATOM   12716 C CA    . THR F 2 374 ? 80.271  134.319 144.912 1.00 50.72  ? 356 THR E CA    1 
ATOM   12717 C C     . THR F 2 374 ? 79.337  133.857 146.020 1.00 50.72  ? 356 THR E C     1 
ATOM   12718 O O     . THR F 2 374 ? 79.621  134.067 147.203 1.00 50.72  ? 356 THR E O     1 
ATOM   12719 C CB    . THR F 2 374 ? 81.564  133.500 144.937 1.00 50.72  ? 356 THR E CB    1 
ATOM   12720 O OG1   . THR F 2 374 ? 82.095  133.469 146.266 1.00 50.72  ? 356 THR E OG1   1 
ATOM   12721 C CG2   . THR F 2 374 ? 82.597  134.105 144.000 1.00 50.72  ? 356 THR E CG2   1 
ATOM   12722 N N     . GLN F 2 375 ? 78.233  133.229 145.633 1.00 53.47  ? 357 GLN E N     1 
ATOM   12723 C CA    . GLN F 2 375 ? 77.232  132.785 146.587 1.00 53.47  ? 357 GLN E CA    1 
ATOM   12724 C C     . GLN F 2 375 ? 77.691  131.497 147.270 1.00 53.47  ? 357 GLN E C     1 
ATOM   12725 O O     . GLN F 2 375 ? 78.558  130.791 146.750 1.00 53.47  ? 357 GLN E O     1 
ATOM   12726 C CB    . GLN F 2 375 ? 75.897  132.553 145.880 1.00 53.47  ? 357 GLN E CB    1 
ATOM   12727 C CG    . GLN F 2 375 ? 75.450  133.675 144.936 1.00 53.47  ? 357 GLN E CG    1 
ATOM   12728 C CD    . GLN F 2 375 ? 75.427  135.062 145.574 1.00 53.47  ? 357 GLN E CD    1 
ATOM   12729 O OE1   . GLN F 2 375 ? 75.749  136.050 144.913 1.00 53.47  ? 357 GLN E OE1   1 
ATOM   12730 N NE2   . GLN F 2 375 ? 75.012  135.152 146.838 1.00 53.47  ? 357 GLN E NE2   1 
ATOM   12731 N N     . PRO F 2 376 ? 77.138  131.158 148.439 1.00 53.88  ? 358 PRO E N     1 
ATOM   12732 C CA    . PRO F 2 376 ? 77.449  129.848 149.020 1.00 53.88  ? 358 PRO E CA    1 
ATOM   12733 C C     . PRO F 2 376 ? 76.849  128.726 148.190 1.00 53.88  ? 358 PRO E C     1 
ATOM   12734 O O     . PRO F 2 376 ? 75.860  128.909 147.478 1.00 53.88  ? 358 PRO E O     1 
ATOM   12735 C CB    . PRO F 2 376 ? 76.816  129.912 150.413 1.00 53.88  ? 358 PRO E CB    1 
ATOM   12736 C CG    . PRO F 2 376 ? 75.731  130.896 150.281 1.00 53.88  ? 358 PRO E CG    1 
ATOM   12737 C CD    . PRO F 2 376 ? 76.257  131.930 149.337 1.00 53.88  ? 358 PRO E CD    1 
ATOM   12738 N N     . TYR F 2 377 ? 77.471  127.555 148.283 1.00 57.46  ? 359 TYR E N     1 
ATOM   12739 C CA    . TYR F 2 377 ? 76.981  126.396 147.552 1.00 57.46  ? 359 TYR E CA    1 
ATOM   12740 C C     . TYR F 2 377 ? 75.626  125.964 148.097 1.00 57.46  ? 359 TYR E C     1 
ATOM   12741 O O     . TYR F 2 377 ? 75.394  125.974 149.309 1.00 57.46  ? 359 TYR E O     1 
ATOM   12742 C CB    . TYR F 2 377 ? 77.977  125.241 147.659 1.00 57.46  ? 359 TYR E CB    1 
ATOM   12743 C CG    . TYR F 2 377 ? 79.241  125.413 146.844 1.00 57.46  ? 359 TYR E CG    1 
ATOM   12744 C CD1   . TYR F 2 377 ? 79.203  125.454 145.457 1.00 57.46  ? 359 TYR E CD1   1 
ATOM   12745 C CD2   . TYR F 2 377 ? 80.477  125.518 147.465 1.00 57.46  ? 359 TYR E CD2   1 
ATOM   12746 C CE1   . TYR F 2 377 ? 80.356  125.608 144.716 1.00 57.46  ? 359 TYR E CE1   1 
ATOM   12747 C CE2   . TYR F 2 377 ? 81.635  125.669 146.731 1.00 57.46  ? 359 TYR E CE2   1 
ATOM   12748 C CZ    . TYR F 2 377 ? 81.568  125.712 145.357 1.00 57.46  ? 359 TYR E CZ    1 
ATOM   12749 O OH    . TYR F 2 377 ? 82.718  125.861 144.619 1.00 57.46  ? 359 TYR E OH    1 
ATOM   12750 N N     . THR F 2 378 ? 74.727  125.586 147.189 1.00 65.39  ? 360 THR E N     1 
ATOM   12751 C CA    . THR F 2 378 ? 73.400  125.118 147.553 1.00 65.39  ? 360 THR E CA    1 
ATOM   12752 C C     . THR F 2 378 ? 73.446  123.620 147.849 1.00 65.39  ? 360 THR E C     1 
ATOM   12753 O O     . THR F 2 378 ? 74.504  122.987 147.820 1.00 65.39  ? 360 THR E O     1 
ATOM   12754 C CB    . THR F 2 378 ? 72.396  125.426 146.442 1.00 65.39  ? 360 THR E CB    1 
ATOM   12755 O OG1   . THR F 2 378 ? 72.684  124.621 145.292 1.00 65.39  ? 360 THR E OG1   1 
ATOM   12756 C CG2   . THR F 2 378 ? 72.443  126.905 146.061 1.00 65.39  ? 360 THR E CG2   1 
ATOM   12757 N N     . ASP F 2 379 ? 72.278  123.045 148.143 1.00 66.84  ? 361 ASP E N     1 
ATOM   12758 C CA    . ASP F 2 379 ? 72.214  121.622 148.468 1.00 66.84  ? 361 ASP E CA    1 
ATOM   12759 C C     . ASP F 2 379 ? 72.561  120.764 147.259 1.00 66.84  ? 361 ASP E C     1 
ATOM   12760 O O     . ASP F 2 379 ? 73.301  119.779 147.380 1.00 66.84  ? 361 ASP E O     1 
ATOM   12761 C CB    . ASP F 2 379 ? 70.826  121.263 148.995 1.00 66.84  ? 361 ASP E CB    1 
ATOM   12762 C CG    . ASP F 2 379 ? 70.393  122.143 150.150 1.00 66.84  ? 361 ASP E CG    1 
ATOM   12763 O OD1   . ASP F 2 379 ? 69.854  123.240 149.893 1.00 66.84  ? 361 ASP E OD1   1 
ATOM   12764 O OD2   . ASP F 2 379 ? 70.591  121.736 151.313 1.00 66.84  ? 361 ASP E OD2   1 
ATOM   12765 N N     . ASP F 2 380 ? 72.037  121.122 146.084 1.00 68.42  ? 362 ASP E N     1 
ATOM   12766 C CA    . ASP F 2 380 ? 72.371  120.386 144.871 1.00 68.42  ? 362 ASP E CA    1 
ATOM   12767 C C     . ASP F 2 380 ? 73.844  120.540 144.520 1.00 68.42  ? 362 ASP E C     1 
ATOM   12768 O O     . ASP F 2 380 ? 74.483  119.580 144.077 1.00 68.42  ? 362 ASP E O     1 
ATOM   12769 C CB    . ASP F 2 380 ? 71.499  120.856 143.710 1.00 68.42  ? 362 ASP E CB    1 
ATOM   12770 C CG    . ASP F 2 380 ? 71.923  120.254 142.386 1.00 68.42  ? 362 ASP E CG    1 
ATOM   12771 O OD1   . ASP F 2 380 ? 72.135  119.024 142.334 1.00 68.42  ? 362 ASP E OD1   1 
ATOM   12772 O OD2   . ASP F 2 380 ? 72.050  121.009 141.400 1.00 68.42  ? 362 ASP E OD2   1 
ATOM   12773 N N     . ASP F 2 381 ? 74.397  121.743 144.703 1.00 66.27  ? 363 ASP E N     1 
ATOM   12774 C CA    . ASP F 2 381 ? 75.816  121.958 144.434 1.00 66.27  ? 363 ASP E CA    1 
ATOM   12775 C C     . ASP F 2 381 ? 76.688  121.133 145.370 1.00 66.27  ? 363 ASP E C     1 
ATOM   12776 O O     . ASP F 2 381 ? 77.686  120.543 144.940 1.00 66.27  ? 363 ASP E O     1 
ATOM   12777 C CB    . ASP F 2 381 ? 76.156  123.442 144.560 1.00 66.27  ? 363 ASP E CB    1 
ATOM   12778 C CG    . ASP F 2 381 ? 75.424  124.295 143.546 1.00 66.27  ? 363 ASP E CG    1 
ATOM   12779 O OD1   . ASP F 2 381 ? 75.490  123.975 142.341 1.00 66.27  ? 363 ASP E OD1   1 
ATOM   12780 O OD2   . ASP F 2 381 ? 74.780  125.284 143.955 1.00 66.27  ? 363 ASP E OD2   1 
ATOM   12781 N N     . ILE F 2 382 ? 76.324  121.079 146.655 1.00 61.42  ? 364 ILE E N     1 
ATOM   12782 C CA    . ILE F 2 382 ? 77.082  120.280 147.614 1.00 61.42  ? 364 ILE E CA    1 
ATOM   12783 C C     . ILE F 2 382 ? 76.995  118.803 147.250 1.00 61.42  ? 364 ILE E C     1 
ATOM   12784 O O     . ILE F 2 382 ? 78.005  118.091 147.260 1.00 61.42  ? 364 ILE E O     1 
ATOM   12785 C CB    . ILE F 2 382 ? 76.587  120.545 149.053 1.00 61.42  ? 364 ILE E CB    1 
ATOM   12786 C CG1   . ILE F 2 382 ? 76.913  121.977 149.502 1.00 61.42  ? 364 ILE E CG1   1 
ATOM   12787 C CG2   . ILE F 2 382 ? 77.218  119.558 150.041 1.00 61.42  ? 364 ILE E CG2   1 
ATOM   12788 C CD1   . ILE F 2 382 ? 76.009  122.498 150.607 1.00 61.42  ? 364 ILE E CD1   1 
ATOM   12789 N N     . ARG F 2 383 ? 75.793  118.330 146.906 1.00 63.41  ? 365 ARG E N     1 
ATOM   12790 C CA    . ARG F 2 383 ? 75.606  116.930 146.528 1.00 63.41  ? 365 ARG E CA    1 
ATOM   12791 C C     . ARG F 2 383 ? 76.423  116.578 145.288 1.00 63.41  ? 365 ARG E C     1 
ATOM   12792 O O     . ARG F 2 383 ? 77.091  115.535 145.248 1.00 63.41  ? 365 ARG E O     1 
ATOM   12793 C CB    . ARG F 2 383 ? 74.112  116.673 146.308 1.00 63.41  ? 365 ARG E CB    1 
ATOM   12794 C CG    . ARG F 2 383 ? 73.703  115.315 145.738 1.00 63.41  ? 365 ARG E CG    1 
ATOM   12795 C CD    . ARG F 2 383 ? 74.236  114.147 146.547 1.00 63.41  ? 365 ARG E CD    1 
ATOM   12796 N NE    . ARG F 2 383 ? 73.667  112.881 146.095 1.00 63.41  ? 365 ARG E NE    1 
ATOM   12797 C CZ    . ARG F 2 383 ? 73.934  112.276 144.943 1.00 63.41  ? 365 ARG E CZ    1 
ATOM   12798 N NH1   . ARG F 2 383 ? 74.807  112.768 144.074 1.00 63.41  ? 365 ARG E NH1   1 
ATOM   12799 N NH2   . ARG F 2 383 ? 73.313  111.136 144.654 1.00 63.41  ? 365 ARG E NH2   1 
ATOM   12800 N N     . LYS F 2 384 ? 76.424  117.464 144.291 1.00 63.53  ? 366 LYS E N     1 
ATOM   12801 C CA    . LYS F 2 384 ? 77.190  117.221 143.074 1.00 63.53  ? 366 LYS E CA    1 
ATOM   12802 C C     . LYS F 2 384 ? 78.687  117.199 143.361 1.00 63.53  ? 366 LYS E C     1 
ATOM   12803 O O     . LYS F 2 384 ? 79.396  116.298 142.901 1.00 63.53  ? 366 LYS E O     1 
ATOM   12804 C CB    . LYS F 2 384 ? 76.843  118.287 142.028 1.00 63.53  ? 366 LYS E CB    1 
ATOM   12805 C CG    . LYS F 2 384 ? 77.586  118.204 140.680 1.00 63.53  ? 366 LYS E CG    1 
ATOM   12806 C CD    . LYS F 2 384 ? 77.336  116.891 139.928 1.00 63.53  ? 366 LYS E CD    1 
ATOM   12807 C CE    . LYS F 2 384 ? 78.171  116.781 138.652 1.00 63.53  ? 366 LYS E CE    1 
ATOM   12808 N NZ    . LYS F 2 384 ? 78.159  118.006 137.801 1.00 63.53  ? 366 LYS E NZ    1 
ATOM   12809 N N     . ILE F 2 385 ? 79.181  118.180 144.127 1.00 60.43  ? 367 ILE E N     1 
ATOM   12810 C CA    . ILE F 2 385 ? 80.616  118.285 144.393 1.00 60.43  ? 367 ILE E CA    1 
ATOM   12811 C C     . ILE F 2 385 ? 81.093  117.077 145.185 1.00 60.43  ? 367 ILE E C     1 
ATOM   12812 O O     . ILE F 2 385 ? 82.171  116.526 144.924 1.00 60.43  ? 367 ILE E O     1 
ATOM   12813 C CB    . ILE F 2 385 ? 80.934  119.604 145.129 1.00 60.43  ? 367 ILE E CB    1 
ATOM   12814 C CG1   . ILE F 2 385 ? 80.681  120.822 144.229 1.00 60.43  ? 367 ILE E CG1   1 
ATOM   12815 C CG2   . ILE F 2 385 ? 82.389  119.630 145.608 1.00 60.43  ? 367 ILE E CG2   1 
ATOM   12816 C CD1   . ILE F 2 385 ? 80.384  122.099 144.991 1.00 60.43  ? 367 ILE E CD1   1 
ATOM   12817 N N     . LEU F 2 386 ? 80.288  116.636 146.151 1.00 59.98  ? 368 LEU E N     1 
ATOM   12818 C CA    . LEU F 2 386 ? 80.612  115.420 146.881 1.00 59.98  ? 368 LEU E CA    1 
ATOM   12819 C C     . LEU F 2 386 ? 80.587  114.202 145.971 1.00 59.98  ? 368 LEU E C     1 
ATOM   12820 O O     . LEU F 2 386 ? 81.383  113.277 146.160 1.00 59.98  ? 368 LEU E O     1 
ATOM   12821 C CB    . LEU F 2 386 ? 79.641  115.251 148.046 1.00 59.98  ? 368 LEU E CB    1 
ATOM   12822 C CG    . LEU F 2 386 ? 79.733  116.339 149.126 1.00 59.98  ? 368 LEU E CG    1 
ATOM   12823 C CD1   . LEU F 2 386 ? 78.451  116.314 149.958 1.00 59.98  ? 368 LEU E CD1   1 
ATOM   12824 C CD2   . LEU F 2 386 ? 81.001  116.200 149.966 1.00 59.98  ? 368 LEU E CD2   1 
ATOM   12825 N N     . GLU F 2 387 ? 79.708  114.187 144.962 1.00 64.52  ? 369 GLU E N     1 
ATOM   12826 C CA    . GLU F 2 387 ? 79.704  113.063 144.029 1.00 64.52  ? 369 GLU E CA    1 
ATOM   12827 C C     . GLU F 2 387 ? 80.989  113.009 143.204 1.00 64.52  ? 369 GLU E C     1 
ATOM   12828 O O     . GLU F 2 387 ? 81.578  111.931 143.046 1.00 64.52  ? 369 GLU E O     1 
ATOM   12829 C CB    . GLU F 2 387 ? 78.480  113.131 143.117 1.00 64.52  ? 369 GLU E CB    1 
ATOM   12830 C CG    . GLU F 2 387 ? 78.411  111.993 142.114 1.00 64.52  ? 369 GLU E CG    1 
ATOM   12831 C CD    . GLU F 2 387 ? 76.993  111.686 141.676 1.00 64.52  ? 369 GLU E CD    1 
ATOM   12832 O OE1   . GLU F 2 387 ? 76.201  111.210 142.516 1.00 64.52  ? 369 GLU E OE1   1 
ATOM   12833 O OE2   . GLU F 2 387 ? 76.671  111.919 140.492 1.00 64.52  ? 369 GLU E OE2   1 
ATOM   12834 N N     . ILE F 2 388 ? 81.452  114.154 142.682 1.00 63.92  ? 370 ILE E N     1 
ATOM   12835 C CA    . ILE F 2 388 ? 82.698  114.126 141.901 1.00 63.92  ? 370 ILE E CA    1 
ATOM   12836 C C     . ILE F 2 388 ? 83.880  113.801 142.808 1.00 63.92  ? 370 ILE E C     1 
ATOM   12837 O O     . ILE F 2 388 ? 84.815  113.105 142.394 1.00 63.92  ? 370 ILE E O     1 
ATOM   12838 C CB    . ILE F 2 388 ? 82.988  115.413 141.083 1.00 63.92  ? 370 ILE E CB    1 
ATOM   12839 C CG1   . ILE F 2 388 ? 81.754  116.126 140.506 1.00 63.92  ? 370 ILE E CG1   1 
ATOM   12840 C CG2   . ILE F 2 388 ? 83.950  115.100 139.916 1.00 63.92  ? 370 ILE E CG2   1 
ATOM   12841 C CD1   . ILE F 2 388 ? 82.055  117.499 139.924 1.00 63.92  ? 370 ILE E CD1   1 
ATOM   12842 N N     . ARG F 2 389 ? 83.866  114.291 144.052 1.00 62.02  ? 371 ARG E N     1 
ATOM   12843 C CA    . ARG F 2 389 ? 84.953  113.951 144.965 1.00 62.02  ? 371 ARG E CA    1 
ATOM   12844 C C     . ARG F 2 389 ? 84.937  112.470 145.322 1.00 62.02  ? 371 ARG E C     1 
ATOM   12845 O O     . ARG F 2 389 ? 85.997  111.878 145.553 1.00 62.02  ? 371 ARG E O     1 
ATOM   12846 C CB    . ARG F 2 389 ? 84.872  114.808 146.230 1.00 62.02  ? 371 ARG E CB    1 
ATOM   12847 C CG    . ARG F 2 389 ? 86.189  114.922 147.005 1.00 62.02  ? 371 ARG E CG    1 
ATOM   12848 C CD    . ARG F 2 389 ? 87.230  115.779 146.281 1.00 62.02  ? 371 ARG E CD    1 
ATOM   12849 N NE    . ARG F 2 389 ? 88.227  116.332 147.193 1.00 62.02  ? 371 ARG E NE    1 
ATOM   12850 C CZ    . ARG F 2 389 ? 89.173  115.638 147.817 1.00 62.02  ? 371 ARG E CZ    1 
ATOM   12851 N NH1   . ARG F 2 389 ? 89.306  114.327 147.659 1.00 62.02  ? 371 ARG E NH1   1 
ATOM   12852 N NH2   . ARG F 2 389 ? 90.018  116.277 148.622 1.00 62.02  ? 371 ARG E NH2   1 
ATOM   12853 N N     . CYS F 2 390 ? 83.754  111.856 145.369 1.00 64.32  ? 372 CYS E N     1 
ATOM   12854 C CA    . CYS F 2 390 ? 83.671  110.421 145.612 1.00 64.32  ? 372 CYS E CA    1 
ATOM   12855 C C     . CYS F 2 390 ? 84.215  109.630 144.429 1.00 64.32  ? 372 CYS E C     1 
ATOM   12856 O O     . CYS F 2 390 ? 84.976  108.673 144.611 1.00 64.32  ? 372 CYS E O     1 
ATOM   12857 C CB    . CYS F 2 390 ? 82.224  110.024 145.898 1.00 64.32  ? 372 CYS E CB    1 
ATOM   12858 S SG    . CYS F 2 390 ? 81.695  110.324 147.592 1.00 64.32  ? 372 CYS E SG    1 
ATOM   12859 N N     . GLN F 2 391 ? 83.825  110.007 143.206 1.00 67.57  ? 373 GLN E N     1 
ATOM   12860 C CA    . GLN F 2 391 ? 84.290  109.259 142.036 1.00 67.57  ? 373 GLN E CA    1 
ATOM   12861 C C     . GLN F 2 391 ? 85.788  109.437 141.820 1.00 67.57  ? 373 GLN E C     1 
ATOM   12862 O O     . GLN F 2 391 ? 86.470  108.498 141.394 1.00 67.57  ? 373 GLN E O     1 
ATOM   12863 C CB    . GLN F 2 391 ? 83.526  109.671 140.771 1.00 67.57  ? 373 GLN E CB    1 
ATOM   12864 C CG    . GLN F 2 391 ? 81.990  109.495 140.761 1.00 67.57  ? 373 GLN E CG    1 
ATOM   12865 C CD    . GLN F 2 391 ? 81.482  108.207 141.396 1.00 67.57  ? 373 GLN E CD    1 
ATOM   12866 O OE1   . GLN F 2 391 ? 82.134  107.165 141.343 1.00 67.57  ? 373 GLN E OE1   1 
ATOM   12867 N NE2   . GLN F 2 391 ? 80.307  108.282 142.010 1.00 67.57  ? 373 GLN E NE2   1 
ATOM   12868 N N     . GLU F 2 392 ? 86.319  110.632 142.091 1.00 68.76  ? 374 GLU E N     1 
ATOM   12869 C CA    . GLU F 2 392 ? 87.763  110.826 142.002 1.00 68.76  ? 374 GLU E CA    1 
ATOM   12870 C C     . GLU F 2 392 ? 88.495  109.989 143.044 1.00 68.76  ? 374 GLU E C     1 
ATOM   12871 O O     . GLU F 2 392 ? 89.551  109.413 142.761 1.00 68.76  ? 374 GLU E O     1 
ATOM   12872 C CB    . GLU F 2 392 ? 88.106  112.306 142.171 1.00 68.76  ? 374 GLU E CB    1 
ATOM   12873 C CG    . GLU F 2 392 ? 87.821  113.151 140.939 1.00 68.76  ? 374 GLU E CG    1 
ATOM   12874 C CD    . GLU F 2 392 ? 88.249  114.598 141.105 1.00 68.76  ? 374 GLU E CD    1 
ATOM   12875 O OE1   . GLU F 2 392 ? 89.246  114.852 141.812 1.00 68.76  ? 374 GLU E OE1   1 
ATOM   12876 O OE2   . GLU F 2 392 ? 87.585  115.484 140.526 1.00 68.76  ? 374 GLU E OE2   1 
ATOM   12877 N N     . GLU F 2 393 ? 87.946  109.910 144.255 1.00 65.07  ? 375 GLU E N     1 
ATOM   12878 C CA    . GLU F 2 393 ? 88.551  109.139 145.334 1.00 65.07  ? 375 GLU E CA    1 
ATOM   12879 C C     . GLU F 2 393 ? 88.326  107.634 145.214 1.00 65.07  ? 375 GLU E C     1 
ATOM   12880 O O     . GLU F 2 393 ? 88.950  106.883 145.972 1.00 65.07  ? 375 GLU E O     1 
ATOM   12881 C CB    . GLU F 2 393 ? 88.002  109.615 146.681 1.00 65.07  ? 375 GLU E CB    1 
ATOM   12882 C CG    . GLU F 2 393 ? 88.585  110.930 147.164 1.00 65.07  ? 375 GLU E CG    1 
ATOM   12883 C CD    . GLU F 2 393 ? 89.638  110.737 148.235 1.00 65.07  ? 375 GLU E CD    1 
ATOM   12884 O OE1   . GLU F 2 393 ? 90.666  110.087 147.952 1.00 65.07  ? 375 GLU E OE1   1 
ATOM   12885 O OE2   . GLU F 2 393 ? 89.436  111.235 149.362 1.00 65.07  ? 375 GLU E OE2   1 
ATOM   12886 N N     . ASP F 2 394 ? 87.463  107.177 144.300 1.00 66.32  ? 376 ASP E N     1 
ATOM   12887 C CA    . ASP F 2 394 ? 87.092  105.765 144.181 1.00 66.32  ? 376 ASP E CA    1 
ATOM   12888 C C     . ASP F 2 394 ? 86.472  105.260 145.487 1.00 66.32  ? 376 ASP E C     1 
ATOM   12889 O O     . ASP F 2 394 ? 86.970  104.333 146.130 1.00 66.32  ? 376 ASP E O     1 
ATOM   12890 C CB    . ASP F 2 394 ? 88.296  104.909 143.767 1.00 66.32  ? 376 ASP E CB    1 
ATOM   12891 C CG    . ASP F 2 394 ? 87.896  103.506 143.348 1.00 66.32  ? 376 ASP E CG    1 
ATOM   12892 O OD1   . ASP F 2 394 ? 87.189  103.367 142.328 1.00 66.32  ? 376 ASP E OD1   1 
ATOM   12893 O OD2   . ASP F 2 394 ? 88.289  102.543 144.039 1.00 66.32  ? 376 ASP E OD2   1 
ATOM   12894 N N     . VAL F 2 395 ? 85.368  105.906 145.866 1.00 64.08  ? 377 VAL E N     1 
ATOM   12895 C CA    . VAL F 2 395 ? 84.642  105.630 147.102 1.00 64.08  ? 377 VAL E CA    1 
ATOM   12896 C C     . VAL F 2 395 ? 83.175  105.434 146.746 1.00 64.08  ? 377 VAL E C     1 
ATOM   12897 O O     . VAL F 2 395 ? 82.585  106.271 146.054 1.00 64.08  ? 377 VAL E O     1 
ATOM   12898 C CB    . VAL F 2 395 ? 84.811  106.769 148.129 1.00 64.08  ? 377 VAL E CB    1 
ATOM   12899 C CG1   . VAL F 2 395 ? 83.864  106.590 149.314 1.00 64.08  ? 377 VAL E CG1   1 
ATOM   12900 C CG2   . VAL F 2 395 ? 86.257  106.853 148.621 1.00 64.08  ? 377 VAL E CG2   1 
ATOM   12901 N N     . GLU F 2 396 ? 82.592  104.336 147.226 1.00 68.91  ? 378 GLU E N     1 
ATOM   12902 C CA    . GLU F 2 396 ? 81.209  103.965 146.943 1.00 68.91  ? 378 GLU E CA    1 
ATOM   12903 C C     . GLU F 2 396 ? 80.351  104.247 148.170 1.00 68.91  ? 378 GLU E C     1 
ATOM   12904 O O     . GLU F 2 396 ? 80.733  103.897 149.292 1.00 68.91  ? 378 GLU E O     1 
ATOM   12905 C CB    . GLU F 2 396 ? 81.123  102.485 146.558 1.00 68.91  ? 378 GLU E CB    1 
ATOM   12906 C CG    . GLU F 2 396 ? 79.770  102.031 145.967 1.00 68.91  ? 378 GLU E CG    1 
ATOM   12907 C CD    . GLU F 2 396 ? 79.639  102.255 144.461 1.00 68.91  ? 378 GLU E CD    1 
ATOM   12908 O OE1   . GLU F 2 396 ? 80.656  102.222 143.736 1.00 68.91  ? 378 GLU E OE1   1 
ATOM   12909 O OE2   . GLU F 2 396 ? 78.498  102.463 143.999 1.00 68.91  ? 378 GLU E OE2   1 
ATOM   12910 N N     . MET F 2 397 ? 79.200  104.886 147.949 1.00 65.03  ? 379 MET E N     1 
ATOM   12911 C CA    . MET F 2 397 ? 78.209  105.145 148.987 1.00 65.03  ? 379 MET E CA    1 
ATOM   12912 C C     . MET F 2 397 ? 76.813  104.859 148.461 1.00 65.03  ? 379 MET E C     1 
ATOM   12913 O O     . MET F 2 397 ? 76.508  105.111 147.293 1.00 65.03  ? 379 MET E O     1 
ATOM   12914 C CB    . MET F 2 397 ? 78.252  106.595 149.491 1.00 65.03  ? 379 MET E CB    1 
ATOM   12915 C CG    . MET F 2 397 ? 79.567  107.008 150.098 1.00 65.03  ? 379 MET E CG    1 
ATOM   12916 S SD    . MET F 2 397 ? 79.482  108.556 151.015 1.00 65.03  ? 379 MET E SD    1 
ATOM   12917 C CE    . MET F 2 397 ? 81.202  109.039 151.013 1.00 65.03  ? 379 MET E CE    1 
ATOM   12918 N N     . ASN F 2 398 ? 75.968  104.331 149.344 1.00 68.93  ? 380 ASN E N     1 
ATOM   12919 C CA    . ASN F 2 398 ? 74.539  104.293 149.077 1.00 68.93  ? 380 ASN E CA    1 
ATOM   12920 C C     . ASN F 2 398 ? 73.949  105.700 149.197 1.00 68.93  ? 380 ASN E C     1 
ATOM   12921 O O     . ASN F 2 398 ? 74.591  106.634 149.686 1.00 68.93  ? 380 ASN E O     1 
ATOM   12922 C CB    . ASN F 2 398 ? 73.841  103.275 149.996 1.00 68.93  ? 380 ASN E CB    1 
ATOM   12923 C CG    . ASN F 2 398 ? 74.017  103.558 151.499 1.00 68.93  ? 380 ASN E CG    1 
ATOM   12924 O OD1   . ASN F 2 398 ? 74.198  104.692 151.943 1.00 68.93  ? 380 ASN E OD1   1 
ATOM   12925 N ND2   . ASN F 2 398 ? 73.963  102.492 152.289 1.00 68.93  ? 380 ASN E ND2   1 
ATOM   12926 N N     . GLU F 2 399 ? 72.706  105.848 148.735 1.00 72.05  ? 381 GLU E N     1 
ATOM   12927 C CA    . GLU F 2 399 ? 72.122  107.181 148.629 1.00 72.05  ? 381 GLU E CA    1 
ATOM   12928 C C     . GLU F 2 399 ? 71.803  107.777 149.996 1.00 72.05  ? 381 GLU E C     1 
ATOM   12929 O O     . GLU F 2 399 ? 71.850  109.001 150.157 1.00 72.05  ? 381 GLU E O     1 
ATOM   12930 C CB    . GLU F 2 399 ? 70.860  107.137 147.763 1.00 72.05  ? 381 GLU E CB    1 
ATOM   12931 C CG    . GLU F 2 399 ? 71.072  106.634 146.331 1.00 72.05  ? 381 GLU E CG    1 
ATOM   12932 C CD    . GLU F 2 399 ? 72.024  107.502 145.523 1.00 72.05  ? 381 GLU E CD    1 
ATOM   12933 O OE1   . GLU F 2 399 ? 71.964  108.741 145.662 1.00 72.05  ? 381 GLU E OE1   1 
ATOM   12934 O OE2   . GLU F 2 399 ? 72.832  106.941 144.754 1.00 72.05  ? 381 GLU E OE2   1 
ATOM   12935 N N     . GLU F 2 400 ? 71.464  106.942 150.982 1.00 68.13  ? 382 GLU E N     1 
ATOM   12936 C CA    . GLU F 2 400 ? 71.200  107.463 152.322 1.00 68.13  ? 382 GLU E CA    1 
ATOM   12937 C C     . GLU F 2 400 ? 72.462  108.054 152.944 1.00 68.13  ? 382 GLU E C     1 
ATOM   12938 O O     . GLU F 2 400 ? 72.414  109.125 153.564 1.00 68.13  ? 382 GLU E O     1 
ATOM   12939 C CB    . GLU F 2 400 ? 70.604  106.368 153.214 1.00 68.13  ? 382 GLU E CB    1 
ATOM   12940 C CG    . GLU F 2 400 ? 71.448  105.102 153.393 1.00 68.13  ? 382 GLU E CG    1 
ATOM   12941 C CD    . GLU F 2 400 ? 70.764  104.067 154.263 1.00 68.13  ? 382 GLU E CD    1 
ATOM   12942 O OE1   . GLU F 2 400 ? 69.575  104.256 154.595 1.00 68.13  ? 382 GLU E OE1   1 
ATOM   12943 O OE2   . GLU F 2 400 ? 71.417  103.061 154.614 1.00 68.13  ? 382 GLU E OE2   1 
ATOM   12944 N N     . ALA F 2 401 ? 73.604  107.385 152.772 1.00 66.99  ? 383 ALA E N     1 
ATOM   12945 C CA    . ALA F 2 401 ? 74.860  107.935 153.267 1.00 66.99  ? 383 ALA E CA    1 
ATOM   12946 C C     . ALA F 2 401 ? 75.220  109.217 152.532 1.00 66.99  ? 383 ALA E C     1 
ATOM   12947 O O     . ALA F 2 401 ? 75.705  110.174 153.146 1.00 66.99  ? 383 ALA E O     1 
ATOM   12948 C CB    . ALA F 2 401 ? 75.980  106.905 153.125 1.00 66.99  ? 383 ALA E CB    1 
ATOM   12949 N N     . LYS F 2 402 ? 74.978  109.257 151.219 1.00 65.85  ? 384 LYS E N     1 
ATOM   12950 C CA    . LYS F 2 402 ? 75.297  110.454 150.444 1.00 65.85  ? 384 LYS E CA    1 
ATOM   12951 C C     . LYS F 2 402 ? 74.438  111.637 150.870 1.00 65.85  ? 384 LYS E C     1 
ATOM   12952 O O     . LYS F 2 402 ? 74.943  112.757 150.994 1.00 65.85  ? 384 LYS E O     1 
ATOM   12953 C CB    . LYS F 2 402 ? 75.130  110.191 148.944 1.00 65.85  ? 384 LYS E CB    1 
ATOM   12954 C CG    . LYS F 2 402 ? 76.443  109.988 148.203 1.00 65.85  ? 384 LYS E CG    1 
ATOM   12955 C CD    . LYS F 2 402 ? 76.222  109.920 146.698 1.00 65.85  ? 384 LYS E CD    1 
ATOM   12956 C CE    . LYS F 2 402 ? 77.520  109.770 145.908 1.00 65.85  ? 384 LYS E CE    1 
ATOM   12957 N NZ    . LYS F 2 402 ? 78.405  108.677 146.395 1.00 65.85  ? 384 LYS E NZ    1 
ATOM   12958 N N     . GLN F 2 403 ? 73.143  111.415 151.118 1.00 64.09  ? 385 GLN E N     1 
ATOM   12959 C CA    . GLN F 2 403 ? 72.294  112.528 151.534 1.00 64.09  ? 385 GLN E CA    1 
ATOM   12960 C C     . GLN F 2 403 ? 72.593  112.951 152.969 1.00 64.09  ? 385 GLN E C     1 
ATOM   12961 O O     . GLN F 2 403 ? 72.501  114.143 153.285 1.00 64.09  ? 385 GLN E O     1 
ATOM   12962 C CB    . GLN F 2 403 ? 70.810  112.177 151.338 1.00 64.09  ? 385 GLN E CB    1 
ATOM   12963 C CG    . GLN F 2 403 ? 70.123  111.343 152.418 1.00 64.09  ? 385 GLN E CG    1 
ATOM   12964 C CD    . GLN F 2 403 ? 68.696  111.001 152.048 1.00 64.09  ? 385 GLN E CD    1 
ATOM   12965 O OE1   . GLN F 2 403 ? 68.191  111.436 151.013 1.00 64.09  ? 385 GLN E OE1   1 
ATOM   12966 N NE2   . GLN F 2 403 ? 68.037  110.217 152.892 1.00 64.09  ? 385 GLN E NE2   1 
ATOM   12967 N N     . LEU F 2 404 ? 72.969  112.011 153.845 1.00 58.56  ? 386 LEU E N     1 
ATOM   12968 C CA    . LEU F 2 404 ? 73.409  112.409 155.181 1.00 58.56  ? 386 LEU E CA    1 
ATOM   12969 C C     . LEU F 2 404 ? 74.681  113.241 155.105 1.00 58.56  ? 386 LEU E C     1 
ATOM   12970 O O     . LEU F 2 404 ? 74.830  114.231 155.829 1.00 58.56  ? 386 LEU E O     1 
ATOM   12971 C CB    . LEU F 2 404 ? 73.633  111.179 156.067 1.00 58.56  ? 386 LEU E CB    1 
ATOM   12972 C CG    . LEU F 2 404 ? 74.251  111.401 157.462 1.00 58.56  ? 386 LEU E CG    1 
ATOM   12973 C CD1   . LEU F 2 404 ? 73.477  112.440 158.270 1.00 58.56  ? 386 LEU E CD1   1 
ATOM   12974 C CD2   . LEU F 2 404 ? 74.316  110.094 158.218 1.00 58.56  ? 386 LEU E CD2   1 
ATOM   12975 N N     . LEU F 2 405 ? 75.612  112.851 154.235 1.00 57.81  ? 387 LEU E N     1 
ATOM   12976 C CA    . LEU F 2 405 ? 76.854  113.597 154.104 1.00 57.81  ? 387 LEU E CA    1 
ATOM   12977 C C     . LEU F 2 405 ? 76.593  114.968 153.487 1.00 57.81  ? 387 LEU E C     1 
ATOM   12978 O O     . LEU F 2 405 ? 77.262  115.945 153.839 1.00 57.81  ? 387 LEU E O     1 
ATOM   12979 C CB    . LEU F 2 405 ? 77.842  112.778 153.269 1.00 57.81  ? 387 LEU E CB    1 
ATOM   12980 C CG    . LEU F 2 405 ? 79.337  113.163 153.276 1.00 57.81  ? 387 LEU E CG    1 
ATOM   12981 C CD1   . LEU F 2 405 ? 80.324  111.974 153.133 1.00 57.81  ? 387 LEU E CD1   1 
ATOM   12982 C CD2   . LEU F 2 405 ? 79.651  114.166 152.211 1.00 57.81  ? 387 LEU E CD2   1 
ATOM   12983 N N     . THR F 2 406 ? 75.618  115.057 152.578 1.00 61.21  ? 388 THR E N     1 
ATOM   12984 C CA    . THR F 2 406 ? 75.194  116.351 152.052 1.00 61.21  ? 388 THR E CA    1 
ATOM   12985 C C     . THR F 2 406 ? 74.603  117.229 153.148 1.00 61.21  ? 388 THR E C     1 
ATOM   12986 O O     . THR F 2 406 ? 74.850  118.439 153.185 1.00 61.21  ? 388 THR E O     1 
ATOM   12987 C CB    . THR F 2 406 ? 74.172  116.151 150.932 1.00 61.21  ? 388 THR E CB    1 
ATOM   12988 O OG1   . THR F 2 406 ? 74.748  115.362 149.884 1.00 61.21  ? 388 THR E OG1   1 
ATOM   12989 C CG2   . THR F 2 406 ? 73.707  117.489 150.375 1.00 61.21  ? 388 THR E CG2   1 
ATOM   12990 N N     . LEU F 2 407 ? 73.801  116.637 154.036 1.00 58.56  ? 389 LEU E N     1 
ATOM   12991 C CA    . LEU F 2 407 ? 73.256  117.389 155.165 1.00 58.56  ? 389 LEU E CA    1 
ATOM   12992 C C     . LEU F 2 407 ? 74.371  117.870 156.084 1.00 58.56  ? 389 LEU E C     1 
ATOM   12993 O O     . LEU F 2 407 ? 74.326  118.995 156.597 1.00 58.56  ? 389 LEU E O     1 
ATOM   12994 C CB    . LEU F 2 407 ? 72.257  116.525 155.940 1.00 58.56  ? 389 LEU E CB    1 
ATOM   12995 C CG    . LEU F 2 407 ? 71.055  117.224 156.582 1.00 58.56  ? 389 LEU E CG    1 
ATOM   12996 C CD1   . LEU F 2 407 ? 69.965  116.201 156.886 1.00 58.56  ? 389 LEU E CD1   1 
ATOM   12997 C CD2   . LEU F 2 407 ? 71.448  117.984 157.845 1.00 58.56  ? 389 LEU E CD2   1 
ATOM   12998 N N     . ILE F 2 408 ? 75.382  117.025 156.296 1.00 54.09  ? 390 ILE E N     1 
ATOM   12999 C CA    . ILE F 2 408 ? 76.534  117.396 157.118 1.00 54.09  ? 390 ILE E CA    1 
ATOM   13000 C C     . ILE F 2 408 ? 77.270  118.567 156.477 1.00 54.09  ? 390 ILE E C     1 
ATOM   13001 O O     . ILE F 2 408 ? 77.672  119.517 157.159 1.00 54.09  ? 390 ILE E O     1 
ATOM   13002 C CB    . ILE F 2 408 ? 77.443  116.156 157.336 1.00 54.09  ? 390 ILE E CB    1 
ATOM   13003 C CG1   . ILE F 2 408 ? 76.957  115.409 158.596 1.00 54.09  ? 390 ILE E CG1   1 
ATOM   13004 C CG2   . ILE F 2 408 ? 78.992  116.526 157.402 1.00 54.09  ? 390 ILE E CG2   1 
ATOM   13005 C CD1   . ILE F 2 408 ? 77.707  114.133 158.982 1.00 54.09  ? 390 ILE E CD1   1 
ATOM   13006 N N     . GLY F 2 409 ? 77.466  118.511 155.160 1.00 55.85  ? 391 GLY E N     1 
ATOM   13007 C CA    . GLY F 2 409 ? 78.154  119.591 154.475 1.00 55.85  ? 391 GLY E CA    1 
ATOM   13008 C C     . GLY F 2 409 ? 77.369  120.888 154.494 1.00 55.85  ? 391 GLY E C     1 
ATOM   13009 O O     . GLY F 2 409 ? 77.945  121.971 154.624 1.00 55.85  ? 391 GLY E O     1 
ATOM   13010 N N     . ARG F 2 410 ? 76.047  120.796 154.349 1.00 59.85  ? 392 ARG E N     1 
ATOM   13011 C CA    . ARG F 2 410 ? 75.203  121.982 154.441 1.00 59.85  ? 392 ARG E CA    1 
ATOM   13012 C C     . ARG F 2 410 ? 75.261  122.586 155.837 1.00 59.85  ? 392 ARG E C     1 
ATOM   13013 O O     . ARG F 2 410 ? 75.304  123.812 155.990 1.00 59.85  ? 392 ARG E O     1 
ATOM   13014 C CB    . ARG F 2 410 ? 73.762  121.619 154.076 1.00 59.85  ? 392 ARG E CB    1 
ATOM   13015 C CG    . ARG F 2 410 ? 72.851  122.806 153.774 1.00 59.85  ? 392 ARG E CG    1 
ATOM   13016 C CD    . ARG F 2 410 ? 71.406  122.498 154.137 1.00 59.85  ? 392 ARG E CD    1 
ATOM   13017 N NE    . ARG F 2 410 ? 71.188  122.515 155.581 1.00 59.85  ? 392 ARG E NE    1 
ATOM   13018 C CZ    . ARG F 2 410 ? 70.164  121.958 156.220 1.00 59.85  ? 392 ARG E CZ    1 
ATOM   13019 N NH1   . ARG F 2 410 ? 69.198  121.314 155.578 1.00 59.85  ? 392 ARG E NH1   1 
ATOM   13020 N NH2   . ARG F 2 410 ? 70.103  122.051 157.545 1.00 59.85  ? 392 ARG E NH2   1 
ATOM   13021 N N     . ASP F 2 411 ? 75.258  121.739 156.868 1.00 57.73  ? 393 ASP E N     1 
ATOM   13022 C CA    . ASP F 2 411 ? 75.203  122.243 158.236 1.00 57.73  ? 393 ASP E CA    1 
ATOM   13023 C C     . ASP F 2 411 ? 76.498  122.944 158.626 1.00 57.73  ? 393 ASP E C     1 
ATOM   13024 O O     . ASP F 2 411 ? 76.467  124.054 159.170 1.00 57.73  ? 393 ASP E O     1 
ATOM   13025 C CB    . ASP F 2 411 ? 74.902  121.100 159.208 1.00 57.73  ? 393 ASP E CB    1 
ATOM   13026 C CG    . ASP F 2 411 ? 73.416  120.854 159.378 1.00 57.73  ? 393 ASP E CG    1 
ATOM   13027 O OD1   . ASP F 2 411 ? 72.650  121.129 158.431 1.00 57.73  ? 393 ASP E OD1   1 
ATOM   13028 O OD2   . ASP F 2 411 ? 73.013  120.389 160.465 1.00 57.73  ? 393 ASP E OD2   1 
ATOM   13029 N N     . THR F 2 412 ? 77.647  122.324 158.333 1.00 51.71  ? 394 THR E N     1 
ATOM   13030 C CA    . THR F 2 412 ? 78.935  122.747 158.875 1.00 51.71  ? 394 THR E CA    1 
ATOM   13031 C C     . THR F 2 412 ? 79.848  123.363 157.822 1.00 51.71  ? 394 THR E C     1 
ATOM   13032 O O     . THR F 2 412 ? 80.169  124.550 157.914 1.00 51.71  ? 394 THR E O     1 
ATOM   13033 C CB    . THR F 2 412 ? 79.629  121.538 159.517 1.00 51.71  ? 394 THR E CB    1 
ATOM   13034 O OG1   . THR F 2 412 ? 79.993  120.600 158.498 1.00 51.71  ? 394 THR E OG1   1 
ATOM   13035 C CG2   . THR F 2 412 ? 78.708  120.852 160.517 1.00 51.71  ? 394 THR E CG2   1 
ATOM   13036 N N     . SER F 2 413 ? 80.240  122.599 156.800 1.00 51.53  ? 395 SER E N     1 
ATOM   13037 C CA    . SER F 2 413 ? 81.152  123.081 155.766 1.00 51.53  ? 395 SER E CA    1 
ATOM   13038 C C     . SER F 2 413 ? 81.374  122.016 154.700 1.00 51.53  ? 395 SER E C     1 
ATOM   13039 O O     . SER F 2 413 ? 81.286  120.819 154.986 1.00 51.53  ? 395 SER E O     1 
ATOM   13040 C CB    . SER F 2 413 ? 82.503  123.484 156.364 1.00 51.53  ? 395 SER E CB    1 
ATOM   13041 O OG    . SER F 2 413 ? 83.489  123.591 155.352 1.00 51.53  ? 395 SER E OG    1 
ATOM   13042 N N     . LEU F 2 414 ? 81.700  122.439 153.478 1.00 53.84  ? 396 LEU E N     1 
ATOM   13043 C CA    . LEU F 2 414 ? 81.948  121.477 152.409 1.00 53.84  ? 396 LEU E CA    1 
ATOM   13044 C C     . LEU F 2 414 ? 83.282  120.763 152.605 1.00 53.84  ? 396 LEU E C     1 
ATOM   13045 O O     . LEU F 2 414 ? 83.390  119.557 152.351 1.00 53.84  ? 396 LEU E O     1 
ATOM   13046 C CB    . LEU F 2 414 ? 81.904  122.186 151.054 1.00 53.84  ? 396 LEU E CB    1 
ATOM   13047 C CG    . LEU F 2 414 ? 82.280  121.402 149.792 1.00 53.84  ? 396 LEU E CG    1 
ATOM   13048 C CD1   . LEU F 2 414 ? 81.479  120.117 149.676 1.00 53.84  ? 396 LEU E CD1   1 
ATOM   13049 C CD2   . LEU F 2 414 ? 82.066  122.270 148.565 1.00 53.84  ? 396 LEU E CD2   1 
ATOM   13050 N N     . ARG F 2 415 ? 84.309  121.491 153.052 1.00 52.45  ? 397 ARG E N     1 
ATOM   13051 C CA    . ARG F 2 415 ? 85.631  120.892 153.210 1.00 52.45  ? 397 ARG E CA    1 
ATOM   13052 C C     . ARG F 2 415 ? 85.639  119.859 154.330 1.00 52.45  ? 397 ARG E C     1 
ATOM   13053 O O     . ARG F 2 415 ? 86.335  118.839 154.239 1.00 52.45  ? 397 ARG E O     1 
ATOM   13054 C CB    . ARG F 2 415 ? 86.664  121.985 153.480 1.00 52.45  ? 397 ARG E CB    1 
ATOM   13055 C CG    . ARG F 2 415 ? 88.089  121.596 153.120 1.00 52.45  ? 397 ARG E CG    1 
ATOM   13056 C CD    . ARG F 2 415 ? 88.495  122.141 151.758 1.00 52.45  ? 397 ARG E CD    1 
ATOM   13057 N NE    . ARG F 2 415 ? 88.710  123.587 151.798 1.00 52.45  ? 397 ARG E NE    1 
ATOM   13058 C CZ    . ARG F 2 415 ? 89.519  124.285 151.006 1.00 52.45  ? 397 ARG E CZ    1 
ATOM   13059 N NH1   . ARG F 2 415 ? 90.215  123.719 150.029 1.00 52.45  ? 397 ARG E NH1   1 
ATOM   13060 N NH2   . ARG F 2 415 ? 89.629  125.597 151.194 1.00 52.45  ? 397 ARG E NH2   1 
ATOM   13061 N N     . TYR F 2 416 ? 84.872  120.108 155.393 1.00 47.98  ? 398 TYR E N     1 
ATOM   13062 C CA    . TYR F 2 416 ? 84.734  119.127 156.464 1.00 47.98  ? 398 TYR E CA    1 
ATOM   13063 C C     . TYR F 2 416 ? 84.095  117.846 155.944 1.00 47.98  ? 398 TYR E C     1 
ATOM   13064 O O     . TYR F 2 416 ? 84.529  116.738 156.282 1.00 47.98  ? 398 TYR E O     1 
ATOM   13065 C CB    . TYR F 2 416 ? 83.907  119.730 157.597 1.00 47.98  ? 398 TYR E CB    1 
ATOM   13066 C CG    . TYR F 2 416 ? 83.511  118.760 158.680 1.00 47.98  ? 398 TYR E CG    1 
ATOM   13067 C CD1   . TYR F 2 416 ? 84.461  118.215 159.529 1.00 47.98  ? 398 TYR E CD1   1 
ATOM   13068 C CD2   . TYR F 2 416 ? 82.186  118.402 158.863 1.00 47.98  ? 398 TYR E CD2   1 
ATOM   13069 C CE1   . TYR F 2 416 ? 84.103  117.337 160.525 1.00 47.98  ? 398 TYR E CE1   1 
ATOM   13070 C CE2   . TYR F 2 416 ? 81.818  117.522 159.855 1.00 47.98  ? 398 TYR E CE2   1 
ATOM   13071 C CZ    . TYR F 2 416 ? 82.780  116.995 160.685 1.00 47.98  ? 398 TYR E CZ    1 
ATOM   13072 O OH    . TYR F 2 416 ? 82.421  116.113 161.677 1.00 47.98  ? 398 TYR E OH    1 
ATOM   13073 N N     . ALA F 2 417 ? 83.082  117.983 155.089 1.00 50.40  ? 399 ALA E N     1 
ATOM   13074 C CA    . ALA F 2 417 ? 82.468  116.819 154.461 1.00 50.40  ? 399 ALA E CA    1 
ATOM   13075 C C     . ALA F 2 417 ? 83.456  116.093 153.553 1.00 50.40  ? 399 ALA E C     1 
ATOM   13076 O O     . ALA F 2 417 ? 83.444  114.857 153.467 1.00 50.40  ? 399 ALA E O     1 
ATOM   13077 C CB    . ALA F 2 417 ? 81.235  117.261 153.678 1.00 50.40  ? 399 ALA E CB    1 
ATOM   13078 N N     . ILE F 2 418 ? 84.319  116.844 152.865 1.00 52.55  ? 400 ILE E N     1 
ATOM   13079 C CA    . ILE F 2 418 ? 85.316  116.220 152.000 1.00 52.55  ? 400 ILE E CA    1 
ATOM   13080 C C     . ILE F 2 418 ? 86.318  115.430 152.835 1.00 52.55  ? 400 ILE E C     1 
ATOM   13081 O O     . ILE F 2 418 ? 86.802  114.375 152.410 1.00 52.55  ? 400 ILE E O     1 
ATOM   13082 C CB    . ILE F 2 418 ? 85.996  117.285 151.114 1.00 52.55  ? 400 ILE E CB    1 
ATOM   13083 C CG1   . ILE F 2 418 ? 85.022  117.756 150.024 1.00 52.55  ? 400 ILE E CG1   1 
ATOM   13084 C CG2   . ILE F 2 418 ? 87.276  116.736 150.454 1.00 52.55  ? 400 ILE E CG2   1 
ATOM   13085 C CD1   . ILE F 2 418 ? 85.361  119.103 149.405 1.00 52.55  ? 400 ILE E CD1   1 
ATOM   13086 N N     . HIS F 2 419 ? 86.655  115.932 154.024 1.00 47.63  ? 401 HIS E N     1 
ATOM   13087 C CA    . HIS F 2 419 ? 87.472  115.144 154.945 1.00 47.63  ? 401 HIS E CA    1 
ATOM   13088 C C     . HIS F 2 419 ? 86.736  113.882 155.383 1.00 47.63  ? 401 HIS E C     1 
ATOM   13089 O O     . HIS F 2 419 ? 87.330  112.795 155.468 1.00 47.63  ? 401 HIS E O     1 
ATOM   13090 C CB    . HIS F 2 419 ? 87.855  115.980 156.166 1.00 47.63  ? 401 HIS E CB    1 
ATOM   13091 C CG    . HIS F 2 419 ? 88.776  117.117 155.857 1.00 47.63  ? 401 HIS E CG    1 
ATOM   13092 N ND1   . HIS F 2 419 ? 89.949  116.956 155.153 1.00 47.63  ? 401 HIS E ND1   1 
ATOM   13093 C CD2   . HIS F 2 419 ? 88.704  118.432 156.171 1.00 47.63  ? 401 HIS E CD2   1 
ATOM   13094 C CE1   . HIS F 2 419 ? 90.555  118.124 155.038 1.00 47.63  ? 401 HIS E CE1   1 
ATOM   13095 N NE2   . HIS F 2 419 ? 89.820  119.036 155.647 1.00 47.63  ? 401 HIS E NE2   1 
ATOM   13096 N N     . LEU F 2 420 ? 85.437  114.010 155.669 1.00 47.75  ? 402 LEU E N     1 
ATOM   13097 C CA    . LEU F 2 420 ? 84.669  112.858 156.120 1.00 47.75  ? 402 LEU E CA    1 
ATOM   13098 C C     . LEU F 2 420 ? 84.521  111.792 155.045 1.00 47.75  ? 402 LEU E C     1 
ATOM   13099 O O     . LEU F 2 420 ? 84.324  110.628 155.396 1.00 47.75  ? 402 LEU E O     1 
ATOM   13100 C CB    . LEU F 2 420 ? 83.277  113.276 156.607 1.00 47.75  ? 402 LEU E CB    1 
ATOM   13101 C CG    . LEU F 2 420 ? 83.086  114.241 157.788 1.00 47.75  ? 402 LEU E CG    1 
ATOM   13102 C CD1   . LEU F 2 420 ? 81.792  113.904 158.515 1.00 47.75  ? 402 LEU E CD1   1 
ATOM   13103 C CD2   . LEU F 2 420 ? 84.258  114.283 158.774 1.00 47.75  ? 402 LEU E CD2   1 
ATOM   13104 N N     . ILE F 2 421 ? 84.605  112.155 153.759 1.00 55.57  ? 403 ILE E N     1 
ATOM   13105 C CA    . ILE F 2 421 ? 84.607  111.136 152.702 1.00 55.57  ? 403 ILE E CA    1 
ATOM   13106 C C     . ILE F 2 421 ? 85.794  110.194 152.882 1.00 55.57  ? 403 ILE E C     1 
ATOM   13107 O O     . ILE F 2 421 ? 85.638  108.966 152.913 1.00 55.57  ? 403 ILE E O     1 
ATOM   13108 C CB    . ILE F 2 421 ? 84.626  111.787 151.303 1.00 55.57  ? 403 ILE E CB    1 
ATOM   13109 C CG1   . ILE F 2 421 ? 83.303  112.503 151.005 1.00 55.57  ? 403 ILE E CG1   1 
ATOM   13110 C CG2   . ILE F 2 421 ? 84.922  110.724 150.202 1.00 55.57  ? 403 ILE E CG2   1 
ATOM   13111 C CD1   . ILE F 2 421 ? 83.367  113.483 149.836 1.00 55.57  ? 403 ILE E CD1   1 
ATOM   13112 N N     . THR F 2 422 ? 86.994  110.763 153.019 1.00 50.27  ? 404 THR E N     1 
ATOM   13113 C CA    . THR F 2 422 ? 88.198  109.956 153.188 1.00 50.27  ? 404 THR E CA    1 
ATOM   13114 C C     . THR F 2 422 ? 88.153  109.168 154.489 1.00 50.27  ? 404 THR E C     1 
ATOM   13115 O O     . THR F 2 422 ? 88.523  107.984 154.527 1.00 50.27  ? 404 THR E O     1 
ATOM   13116 C CB    . THR F 2 422 ? 89.427  110.863 153.164 1.00 50.27  ? 404 THR E CB    1 
ATOM   13117 O OG1   . THR F 2 422 ? 89.262  111.869 152.157 1.00 50.27  ? 404 THR E OG1   1 
ATOM   13118 C CG2   . THR F 2 422 ? 90.682  110.073 152.875 1.00 50.27  ? 404 THR E CG2   1 
ATOM   13119 N N     . ALA F 2 423 ? 87.696  109.813 155.565 1.00 48.68  ? 405 ALA E N     1 
ATOM   13120 C CA    . ALA F 2 423 ? 87.639  109.139 156.857 1.00 48.68  ? 405 ALA E CA    1 
ATOM   13121 C C     . ALA F 2 423 ? 86.650  107.977 156.843 1.00 48.68  ? 405 ALA E C     1 
ATOM   13122 O O     . ALA F 2 423 ? 86.947  106.900 157.369 1.00 48.68  ? 405 ALA E O     1 
ATOM   13123 C CB    . ALA F 2 423 ? 87.284  110.145 157.944 1.00 48.68  ? 405 ALA E CB    1 
ATOM   13124 N N     . ALA F 2 424 ? 85.480  108.164 156.227 1.00 53.19  ? 406 ALA E N     1 
ATOM   13125 C CA    . ALA F 2 424 ? 84.500  107.087 156.152 1.00 53.19  ? 406 ALA E CA    1 
ATOM   13126 C C     . ALA F 2 424 ? 84.980  105.964 155.245 1.00 53.19  ? 406 ALA E C     1 
ATOM   13127 O O     . ALA F 2 424 ? 84.707  104.788 155.514 1.00 53.19  ? 406 ALA E O     1 
ATOM   13128 C CB    . ALA F 2 424 ? 83.161  107.634 155.666 1.00 53.19  ? 406 ALA E CB    1 
ATOM   13129 N N     . ALA F 2 425 ? 85.695  106.304 154.167 1.00 53.82  ? 407 ALA E N     1 
ATOM   13130 C CA    . ALA F 2 425 ? 86.252  105.275 153.295 1.00 53.82  ? 407 ALA E CA    1 
ATOM   13131 C C     . ALA F 2 425 ? 87.255  104.407 154.045 1.00 53.82  ? 407 ALA E C     1 
ATOM   13132 O O     . ALA F 2 425 ? 87.208  103.173 153.967 1.00 53.82  ? 407 ALA E O     1 
ATOM   13133 C CB    . ALA F 2 425 ? 86.906  105.923 152.077 1.00 53.82  ? 407 ALA E CB    1 
ATOM   13134 N N     . LEU F 2 426 ? 88.151  105.036 154.808 1.00 50.22  ? 408 LEU E N     1 
ATOM   13135 C CA    . LEU F 2 426 ? 89.112  104.251 155.579 1.00 50.22  ? 408 LEU E CA    1 
ATOM   13136 C C     . LEU F 2 426 ? 88.440  103.483 156.711 1.00 50.22  ? 408 LEU E C     1 
ATOM   13137 O O     . LEU F 2 426 ? 88.874  102.374 157.041 1.00 50.22  ? 408 LEU E O     1 
ATOM   13138 C CB    . LEU F 2 426 ? 90.227  105.141 156.130 1.00 50.22  ? 408 LEU E CB    1 
ATOM   13139 C CG    . LEU F 2 426 ? 91.446  105.320 155.214 1.00 50.22  ? 408 LEU E CG    1 
ATOM   13140 C CD1   . LEU F 2 426 ? 92.340  104.089 155.244 1.00 50.22  ? 408 LEU E CD1   1 
ATOM   13141 C CD2   . LEU F 2 426 ? 91.060  105.668 153.778 1.00 50.22  ? 408 LEU E CD2   1 
ATOM   13142 N N     . SER F 2 427 ? 87.391  104.046 157.316 1.00 52.12  ? 409 SER E N     1 
ATOM   13143 C CA    . SER F 2 427 ? 86.676  103.329 158.366 1.00 52.12  ? 409 SER E CA    1 
ATOM   13144 C C     . SER F 2 427 ? 85.992  102.084 157.818 1.00 52.12  ? 409 SER E C     1 
ATOM   13145 O O     . SER F 2 427 ? 86.006  101.029 158.462 1.00 52.12  ? 409 SER E O     1 
ATOM   13146 C CB    . SER F 2 427 ? 85.655  104.251 159.029 1.00 52.12  ? 409 SER E CB    1 
ATOM   13147 O OG    . SER F 2 427 ? 84.934  103.566 160.038 1.00 52.12  ? 409 SER E OG    1 
ATOM   13148 N N     . CYS F 2 428 ? 85.384  102.185 156.633 1.00 61.55  ? 410 CYS E N     1 
ATOM   13149 C CA    . CYS F 2 428 ? 84.763  101.009 156.029 1.00 61.55  ? 410 CYS E CA    1 
ATOM   13150 C C     . CYS F 2 428 ? 85.812  99.992  155.602 1.00 61.55  ? 410 CYS E C     1 
ATOM   13151 O O     . CYS F 2 428 ? 85.598  98.782  155.738 1.00 61.55  ? 410 CYS E O     1 
ATOM   13152 C CB    . CYS F 2 428 ? 83.907  101.408 154.832 1.00 61.55  ? 410 CYS E CB    1 
ATOM   13153 S SG    . CYS F 2 428 ? 84.786  101.303 153.258 1.00 61.55  ? 410 CYS E SG    1 
ATOM   13154 N N     . GLN F 2 429 ? 86.945  100.461 155.070 1.00 57.81  ? 411 GLN E N     1 
ATOM   13155 C CA    . GLN F 2 429 ? 88.007  99.542  154.671 1.00 57.81  ? 411 GLN E CA    1 
ATOM   13156 C C     . GLN F 2 429 ? 88.592  98.812  155.872 1.00 57.81  ? 411 GLN E C     1 
ATOM   13157 O O     . GLN F 2 429 ? 88.999  97.650  155.753 1.00 57.81  ? 411 GLN E O     1 
ATOM   13158 C CB    . GLN F 2 429 ? 89.099  100.307 153.920 1.00 57.81  ? 411 GLN E CB    1 
ATOM   13159 C CG    . GLN F 2 429 ? 90.101  99.426  153.155 1.00 57.81  ? 411 GLN E CG    1 
ATOM   13160 C CD    . GLN F 2 429 ? 91.303  98.971  153.978 1.00 57.81  ? 411 GLN E CD    1 
ATOM   13161 O OE1   . GLN F 2 429 ? 91.472  99.350  155.137 1.00 57.81  ? 411 GLN E OE1   1 
ATOM   13162 N NE2   . GLN F 2 429 ? 92.149  98.149  153.368 1.00 57.81  ? 411 GLN E NE2   1 
ATOM   13163 N N     . LYS F 2 430 ? 88.653  99.474  157.029 1.00 53.97  ? 412 LYS E N     1 
ATOM   13164 C CA    . LYS F 2 430 ? 89.156  98.818  158.233 1.00 53.97  ? 412 LYS E CA    1 
ATOM   13165 C C     . LYS F 2 430 ? 88.226  97.697  158.684 1.00 53.97  ? 412 LYS E C     1 
ATOM   13166 O O     . LYS F 2 430 ? 88.688  96.651  159.154 1.00 53.97  ? 412 LYS E O     1 
ATOM   13167 C CB    . LYS F 2 430 ? 89.334  99.845  159.349 1.00 53.97  ? 412 LYS E CB    1 
ATOM   13168 C CG    . LYS F 2 430 ? 90.363  99.450  160.402 1.00 53.97  ? 412 LYS E CG    1 
ATOM   13169 C CD    . LYS F 2 430 ? 90.002  99.971  161.791 1.00 53.97  ? 412 LYS E CD    1 
ATOM   13170 C CE    . LYS F 2 430 ? 90.087  101.490 161.856 1.00 53.97  ? 412 LYS E CE    1 
ATOM   13171 N NZ    . LYS F 2 430 ? 90.052  102.006 163.250 1.00 53.97  ? 412 LYS E NZ    1 
ATOM   13172 N N     . ARG F 2 431 ? 86.915  97.895  158.545 1.00 66.25  ? 413 ARG E N     1 
ATOM   13173 C CA    . ARG F 2 431 ? 85.916  96.921  158.969 1.00 66.25  ? 413 ARG E CA    1 
ATOM   13174 C C     . ARG F 2 431 ? 85.693  95.796  157.944 1.00 66.25  ? 413 ARG E C     1 
ATOM   13175 O O     . ARG F 2 431 ? 84.799  94.971  158.148 1.00 66.25  ? 413 ARG E O     1 
ATOM   13176 C CB    . ARG F 2 431 ? 84.602  97.658  159.266 1.00 66.25  ? 413 ARG E CB    1 
ATOM   13177 C CG    . ARG F 2 431 ? 83.539  96.865  160.093 1.00 66.25  ? 413 ARG E CG    1 
ATOM   13178 C CD    . ARG F 2 431 ? 82.309  96.258  159.352 1.00 66.25  ? 413 ARG E CD    1 
ATOM   13179 N NE    . ARG F 2 431 ? 81.862  96.963  158.152 1.00 66.25  ? 413 ARG E NE    1 
ATOM   13180 C CZ    . ARG F 2 431 ? 81.322  98.177  158.127 1.00 66.25  ? 413 ARG E CZ    1 
ATOM   13181 N NH1   . ARG F 2 431 ? 81.131  98.887  159.232 1.00 66.25  ? 413 ARG E NH1   1 
ATOM   13182 N NH2   . ARG F 2 431 ? 80.961  98.698  156.958 1.00 66.25  ? 413 ARG E NH2   1 
ATOM   13183 N N     . LYS F 2 432 ? 86.481  95.735  156.863 1.00 74.57  ? 414 LYS E N     1 
ATOM   13184 C CA    . LYS F 2 432 ? 86.392  94.745  155.787 1.00 74.57  ? 414 LYS E CA    1 
ATOM   13185 C C     . LYS F 2 432 ? 85.145  94.890  154.919 1.00 74.57  ? 414 LYS E C     1 
ATOM   13186 O O     . LYS F 2 432 ? 84.897  94.023  154.072 1.00 74.57  ? 414 LYS E O     1 
ATOM   13187 C CB    . LYS F 2 432 ? 86.466  93.301  156.306 1.00 74.57  ? 414 LYS E CB    1 
ATOM   13188 C CG    . LYS F 2 432 ? 87.552  93.044  157.349 1.00 74.57  ? 414 LYS E CG    1 
ATOM   13189 C CD    . LYS F 2 432 ? 87.657  91.562  157.694 1.00 74.57  ? 414 LYS E CD    1 
ATOM   13190 C CE    . LYS F 2 432 ? 88.444  90.780  156.647 1.00 74.57  ? 414 LYS E CE    1 
ATOM   13191 N NZ    . LYS F 2 432 ? 88.690  89.374  157.069 1.00 74.57  ? 414 LYS E NZ    1 
ATOM   13192 N N     . GLY F 2 433 ? 84.353  95.957  155.089 1.00 73.85  ? 415 GLY E N     1 
ATOM   13193 C CA    . GLY F 2 433 ? 83.292  96.251  154.151 1.00 73.85  ? 415 GLY E CA    1 
ATOM   13194 C C     . GLY F 2 433 ? 83.842  96.849  152.872 1.00 73.85  ? 415 GLY E C     1 
ATOM   13195 O O     . GLY F 2 433 ? 85.031  97.158  152.782 1.00 73.85  ? 415 GLY E O     1 
ATOM   13196 N N     . LYS F 2 434 ? 82.949  96.996  151.887 1.00 72.42  ? 416 LYS E N     1 
ATOM   13197 C CA    . LYS F 2 434 ? 83.266  97.566  150.580 1.00 72.42  ? 416 LYS E CA    1 
ATOM   13198 C C     . LYS F 2 434 ? 82.541  98.885  150.343 1.00 72.42  ? 416 LYS E C     1 
ATOM   13199 O O     . LYS F 2 434 ? 83.190  99.902  150.082 1.00 72.42  ? 416 LYS E O     1 
ATOM   13200 C CB    . LYS F 2 434 ? 82.919  96.545  149.476 1.00 72.42  ? 416 LYS E CB    1 
ATOM   13201 C CG    . LYS F 2 434 ? 83.633  96.669  148.092 1.00 72.42  ? 416 LYS E CG    1 
ATOM   13202 C CD    . LYS F 2 434 ? 85.150  96.978  148.081 1.00 72.42  ? 416 LYS E CD    1 
ATOM   13203 C CE    . LYS F 2 434 ? 86.003  95.944  148.823 1.00 72.42  ? 416 LYS E CE    1 
ATOM   13204 N NZ    . LYS F 2 434 ? 87.312  96.519  149.242 1.00 72.42  ? 416 LYS E NZ    1 
ATOM   13205 N N     . VAL F 2 435 ? 81.213  98.897  150.441 1.00 69.18  ? 417 VAL E N     1 
ATOM   13206 C CA    . VAL F 2 435 ? 80.424  100.112 150.259 1.00 69.18  ? 417 VAL E CA    1 
ATOM   13207 C C     . VAL F 2 435 ? 80.359  100.843 151.593 1.00 69.18  ? 417 VAL E C     1 
ATOM   13208 O O     . VAL F 2 435 ? 80.101  100.233 152.638 1.00 69.18  ? 417 VAL E O     1 
ATOM   13209 C CB    . VAL F 2 435 ? 79.015  99.792  149.715 1.00 69.18  ? 417 VAL E CB    1 
ATOM   13210 C CG1   . VAL F 2 435 ? 78.150  98.998  150.723 1.00 69.18  ? 417 VAL E CG1   1 
ATOM   13211 C CG2   . VAL F 2 435 ? 78.293  101.072 149.249 1.00 69.18  ? 417 VAL E CG2   1 
ATOM   13212 N N     . VAL F 2 436 ? 80.616  102.145 151.563 1.00 62.92  ? 418 VAL E N     1 
ATOM   13213 C CA    . VAL F 2 436 ? 80.609  102.961 152.771 1.00 62.92  ? 418 VAL E CA    1 
ATOM   13214 C C     . VAL F 2 436 ? 79.157  103.208 153.166 1.00 62.92  ? 418 VAL E C     1 
ATOM   13215 O O     . VAL F 2 436 ? 78.372  103.740 152.375 1.00 62.92  ? 418 VAL E O     1 
ATOM   13216 C CB    . VAL F 2 436 ? 81.361  104.282 152.548 1.00 62.92  ? 418 VAL E CB    1 
ATOM   13217 C CG1   . VAL F 2 436 ? 81.111  105.272 153.685 1.00 62.92  ? 418 VAL E CG1   1 
ATOM   13218 C CG2   . VAL F 2 436 ? 82.854  104.046 152.373 1.00 62.92  ? 418 VAL E CG2   1 
ATOM   13219 N N     . GLU F 2 437 ? 78.809  102.834 154.393 1.00 64.11  ? 419 GLU E N     1 
ATOM   13220 C CA    . GLU F 2 437 ? 77.441  102.866 154.891 1.00 64.11  ? 419 GLU E CA    1 
ATOM   13221 C C     . GLU F 2 437 ? 77.212  104.103 155.757 1.00 64.11  ? 419 GLU E C     1 
ATOM   13222 O O     . GLU F 2 437 ? 78.134  104.856 156.074 1.00 64.11  ? 419 GLU E O     1 
ATOM   13223 C CB    . GLU F 2 437 ? 77.139  101.585 155.680 1.00 64.11  ? 419 GLU E CB    1 
ATOM   13224 C CG    . GLU F 2 437 ? 77.156  100.309 154.839 1.00 64.11  ? 419 GLU E CG    1 
ATOM   13225 C CD    . GLU F 2 437 ? 77.781  99.137  155.569 1.00 64.11  ? 419 GLU E CD    1 
ATOM   13226 O OE1   . GLU F 2 437 ? 77.101  98.539  156.428 1.00 64.11  ? 419 GLU E OE1   1 
ATOM   13227 O OE2   . GLU F 2 437 ? 78.952  98.813  155.282 1.00 64.11  ? 419 GLU E OE2   1 
ATOM   13228 N N     . VAL F 2 438 ? 75.948  104.305 156.135 1.00 61.86  ? 420 VAL E N     1 
ATOM   13229 C CA    . VAL F 2 438 ? 75.574  105.456 156.951 1.00 61.86  ? 420 VAL E CA    1 
ATOM   13230 C C     . VAL F 2 438 ? 76.180  105.359 158.351 1.00 61.86  ? 420 VAL E C     1 
ATOM   13231 O O     . VAL F 2 438 ? 76.501  106.385 158.968 1.00 61.86  ? 420 VAL E O     1 
ATOM   13232 C CB    . VAL F 2 438 ? 74.035  105.581 156.981 1.00 61.86  ? 420 VAL E CB    1 
ATOM   13233 C CG1   . VAL F 2 438 ? 73.396  104.505 157.859 1.00 61.86  ? 420 VAL E CG1   1 
ATOM   13234 C CG2   . VAL F 2 438 ? 73.600  106.968 157.426 1.00 61.86  ? 420 VAL E CG2   1 
ATOM   13235 N N     . GLU F 2 439 ? 76.340  104.140 158.877 1.00 60.74  ? 421 GLU E N     1 
ATOM   13236 C CA    . GLU F 2 439 ? 76.889  103.971 160.220 1.00 60.74  ? 421 GLU E CA    1 
ATOM   13237 C C     . GLU F 2 439 ? 78.343  104.421 160.286 1.00 60.74  ? 421 GLU E C     1 
ATOM   13238 O O     . GLU F 2 439 ? 78.779  104.981 161.300 1.00 60.74  ? 421 GLU E O     1 
ATOM   13239 C CB    . GLU F 2 439 ? 76.759  102.512 160.667 1.00 60.74  ? 421 GLU E CB    1 
ATOM   13240 C CG    . GLU F 2 439 ? 77.517  101.487 159.807 1.00 60.74  ? 421 GLU E CG    1 
ATOM   13241 C CD    . GLU F 2 439 ? 76.975  100.074 159.948 1.00 60.74  ? 421 GLU E CD    1 
ATOM   13242 O OE1   . GLU F 2 439 ? 75.742  99.887  159.877 1.00 60.74  ? 421 GLU E OE1   1 
ATOM   13243 O OE2   . GLU F 2 439 ? 77.789  99.145  160.131 1.00 60.74  ? 421 GLU E OE2   1 
ATOM   13244 N N     . ASP F 2 440 ? 79.108  104.183 159.217 1.00 58.11  ? 422 ASP E N     1 
ATOM   13245 C CA    . ASP F 2 440 ? 80.485  104.665 159.168 1.00 58.11  ? 422 ASP E CA    1 
ATOM   13246 C C     . ASP F 2 440 ? 80.532  106.186 159.200 1.00 58.11  ? 422 ASP E C     1 
ATOM   13247 O O     . ASP F 2 440 ? 81.397  106.775 159.861 1.00 58.11  ? 422 ASP E O     1 
ATOM   13248 C CB    . ASP F 2 440 ? 81.182  104.137 157.916 1.00 58.11  ? 422 ASP E CB    1 
ATOM   13249 C CG    . ASP F 2 440 ? 81.677  102.716 158.081 1.00 58.11  ? 422 ASP E CG    1 
ATOM   13250 O OD1   . ASP F 2 440 ? 82.780  102.530 158.637 1.00 58.11  ? 422 ASP E OD1   1 
ATOM   13251 O OD2   . ASP F 2 440 ? 80.966  101.783 157.654 1.00 58.11  ? 422 ASP E OD2   1 
ATOM   13252 N N     . ILE F 2 441 ? 79.603  106.840 158.502 1.00 53.37  ? 423 ILE E N     1 
ATOM   13253 C CA    . ILE F 2 441 ? 79.556  108.297 158.516 1.00 53.37  ? 423 ILE E CA    1 
ATOM   13254 C C     . ILE F 2 441 ? 79.182  108.802 159.902 1.00 53.37  ? 423 ILE E C     1 
ATOM   13255 O O     . ILE F 2 441 ? 79.708  109.821 160.363 1.00 53.37  ? 423 ILE E O     1 
ATOM   13256 C CB    . ILE F 2 441 ? 78.584  108.812 157.434 1.00 53.37  ? 423 ILE E CB    1 
ATOM   13257 C CG1   . ILE F 2 441 ? 79.176  108.597 156.030 1.00 53.37  ? 423 ILE E CG1   1 
ATOM   13258 C CG2   . ILE F 2 441 ? 78.184  110.289 157.667 1.00 53.37  ? 423 ILE E CG2   1 
ATOM   13259 C CD1   . ILE F 2 441 ? 80.244  109.598 155.607 1.00 53.37  ? 423 ILE E CD1   1 
ATOM   13260 N N     . GLN F 2 442 ? 78.257  108.117 160.580 1.00 54.37  ? 424 GLN E N     1 
ATOM   13261 C CA    . GLN F 2 442 ? 77.891  108.530 161.933 1.00 54.37  ? 424 GLN E CA    1 
ATOM   13262 C C     . GLN F 2 442 ? 79.070  108.378 162.889 1.00 54.37  ? 424 GLN E C     1 
ATOM   13263 O O     . GLN F 2 442 ? 79.318  109.255 163.727 1.00 54.37  ? 424 GLN E O     1 
ATOM   13264 C CB    . GLN F 2 442 ? 76.689  107.723 162.423 1.00 54.37  ? 424 GLN E CB    1 
ATOM   13265 C CG    . GLN F 2 442 ? 75.389  107.991 161.664 1.00 54.37  ? 424 GLN E CG    1 
ATOM   13266 C CD    . GLN F 2 442 ? 74.707  109.279 162.088 1.00 54.37  ? 424 GLN E CD    1 
ATOM   13267 O OE1   . GLN F 2 442 ? 75.329  110.164 162.673 1.00 54.37  ? 424 GLN E OE1   1 
ATOM   13268 N NE2   . GLN F 2 442 ? 73.418  109.390 161.789 1.00 54.37  ? 424 GLN E NE2   1 
ATOM   13269 N N     . ARG F 2 443 ? 79.823  107.281 162.754 1.00 48.08  ? 425 ARG E N     1 
ATOM   13270 C CA    . ARG F 2 443 ? 81.027  107.080 163.559 1.00 48.08  ? 425 ARG E CA    1 
ATOM   13271 C C     . ARG F 2 443 ? 82.052  108.179 163.299 1.00 48.08  ? 425 ARG E C     1 
ATOM   13272 O O     . ARG F 2 443 ? 82.639  108.734 164.235 1.00 48.08  ? 425 ARG E O     1 
ATOM   13273 C CB    . ARG F 2 443 ? 81.619  105.701 163.248 1.00 48.08  ? 425 ARG E CB    1 
ATOM   13274 C CG    . ARG F 2 443 ? 82.931  105.347 163.958 1.00 48.08  ? 425 ARG E CG    1 
ATOM   13275 C CD    . ARG F 2 443 ? 83.378  103.945 163.594 1.00 48.08  ? 425 ARG E CD    1 
ATOM   13276 N NE    . ARG F 2 443 ? 84.689  103.645 164.175 1.00 48.08  ? 425 ARG E NE    1 
ATOM   13277 C CZ    . ARG F 2 443 ? 85.743  103.119 163.554 1.00 48.08  ? 425 ARG E CZ    1 
ATOM   13278 N NH1   . ARG F 2 443 ? 85.698  102.709 162.293 1.00 48.08  ? 425 ARG E NH1   1 
ATOM   13279 N NH2   . ARG F 2 443 ? 86.883  102.985 164.226 1.00 48.08  ? 425 ARG E NH2   1 
ATOM   13280 N N     . VAL F 2 444 ? 82.276  108.507 162.028 1.00 44.88  ? 426 VAL E N     1 
ATOM   13281 C CA    . VAL F 2 444 ? 83.297  109.492 161.685 1.00 44.88  ? 426 VAL E CA    1 
ATOM   13282 C C     . VAL F 2 444 ? 82.878  110.881 162.153 1.00 44.88  ? 426 VAL E C     1 
ATOM   13283 O O     . VAL F 2 444 ? 83.715  111.678 162.590 1.00 44.88  ? 426 VAL E O     1 
ATOM   13284 C CB    . VAL F 2 444 ? 83.581  109.431 160.171 1.00 44.88  ? 426 VAL E CB    1 
ATOM   13285 C CG1   . VAL F 2 444 ? 84.173  110.719 159.624 1.00 44.88  ? 426 VAL E CG1   1 
ATOM   13286 C CG2   . VAL F 2 444 ? 84.517  108.278 159.882 1.00 44.88  ? 426 VAL E CG2   1 
ATOM   13287 N N     . TYR F 2 445 ? 81.586  111.201 162.061 1.00 48.71  ? 427 TYR E N     1 
ATOM   13288 C CA    . TYR F 2 445 ? 81.107  112.470 162.595 1.00 48.71  ? 427 TYR E CA    1 
ATOM   13289 C C     . TYR F 2 445 ? 81.249  112.515 164.110 1.00 48.71  ? 427 TYR E C     1 
ATOM   13290 O O     . TYR F 2 445 ? 81.517  113.577 164.682 1.00 48.71  ? 427 TYR E O     1 
ATOM   13291 C CB    . TYR F 2 445 ? 79.653  112.699 162.186 1.00 48.71  ? 427 TYR E CB    1 
ATOM   13292 C CG    . TYR F 2 445 ? 79.094  114.027 162.643 1.00 48.71  ? 427 TYR E CG    1 
ATOM   13293 C CD1   . TYR F 2 445 ? 79.370  115.194 161.947 1.00 48.71  ? 427 TYR E CD1   1 
ATOM   13294 C CD2   . TYR F 2 445 ? 78.283  114.112 163.766 1.00 48.71  ? 427 TYR E CD2   1 
ATOM   13295 C CE1   . TYR F 2 445 ? 78.860  116.408 162.357 1.00 48.71  ? 427 TYR E CE1   1 
ATOM   13296 C CE2   . TYR F 2 445 ? 77.769  115.324 164.185 1.00 48.71  ? 427 TYR E CE2   1 
ATOM   13297 C CZ    . TYR F 2 445 ? 78.062  116.468 163.476 1.00 48.71  ? 427 TYR E CZ    1 
ATOM   13298 O OH    . TYR F 2 445 ? 77.553  117.678 163.885 1.00 48.71  ? 427 TYR E OH    1 
ATOM   13299 N N     . ARG F 2 446 ? 81.061  111.374 164.779 1.00 45.23  ? 428 ARG E N     1 
ATOM   13300 C CA    . ARG F 2 446 ? 81.278  111.327 166.220 1.00 45.23  ? 428 ARG E CA    1 
ATOM   13301 C C     . ARG F 2 446 ? 82.743  111.573 166.564 1.00 45.23  ? 428 ARG E C     1 
ATOM   13302 O O     . ARG F 2 446 ? 83.048  112.277 167.533 1.00 45.23  ? 428 ARG E O     1 
ATOM   13303 C CB    . ARG F 2 446 ? 80.804  109.981 166.773 1.00 45.23  ? 428 ARG E CB    1 
ATOM   13304 C CG    . ARG F 2 446 ? 81.087  109.749 168.255 1.00 45.23  ? 428 ARG E CG    1 
ATOM   13305 C CD    . ARG F 2 446 ? 80.330  108.541 168.774 1.00 45.23  ? 428 ARG E CD    1 
ATOM   13306 N NE    . ARG F 2 446 ? 80.741  107.313 168.100 1.00 45.23  ? 428 ARG E NE    1 
ATOM   13307 C CZ    . ARG F 2 446 ? 81.852  106.627 168.349 1.00 45.23  ? 428 ARG E CZ    1 
ATOM   13308 N NH1   . ARG F 2 446 ? 82.737  107.024 169.254 1.00 45.23  ? 428 ARG E NH1   1 
ATOM   13309 N NH2   . ARG F 2 446 ? 82.087  105.511 167.666 1.00 45.23  ? 428 ARG E NH2   1 
ATOM   13310 N N     . LEU F 2 447 ? 83.664  111.007 165.779 1.00 40.27  ? 429 LEU E N     1 
ATOM   13311 C CA    . LEU F 2 447 ? 85.085  111.116 166.105 1.00 40.27  ? 429 LEU E CA    1 
ATOM   13312 C C     . LEU F 2 447 ? 85.653  112.480 165.725 1.00 40.27  ? 429 LEU E C     1 
ATOM   13313 O O     . LEU F 2 447 ? 86.086  113.245 166.593 1.00 40.27  ? 429 LEU E O     1 
ATOM   13314 C CB    . LEU F 2 447 ? 85.874  110.005 165.405 1.00 40.27  ? 429 LEU E CB    1 
ATOM   13315 C CG    . LEU F 2 447 ? 85.625  108.548 165.807 1.00 40.27  ? 429 LEU E CG    1 
ATOM   13316 C CD1   . LEU F 2 447 ? 86.464  107.627 164.940 1.00 40.27  ? 429 LEU E CD1   1 
ATOM   13317 C CD2   . LEU F 2 447 ? 85.928  108.301 167.274 1.00 40.27  ? 429 LEU E CD2   1 
ATOM   13318 N N     . PHE F 2 448 ? 85.653  112.805 164.433 1.00 37.91  ? 430 PHE E N     1 
ATOM   13319 C CA    . PHE F 2 448 ? 86.279  114.025 163.934 1.00 37.91  ? 430 PHE E CA    1 
ATOM   13320 C C     . PHE F 2 448 ? 85.297  115.182 164.034 1.00 37.91  ? 430 PHE E C     1 
ATOM   13321 O O     . PHE F 2 448 ? 84.181  115.103 163.513 1.00 37.91  ? 430 PHE E O     1 
ATOM   13322 C CB    . PHE F 2 448 ? 86.733  113.865 162.478 1.00 37.91  ? 430 PHE E CB    1 
ATOM   13323 C CG    . PHE F 2 448 ? 87.834  112.834 162.244 1.00 37.91  ? 430 PHE E CG    1 
ATOM   13324 C CD1   . PHE F 2 448 ? 88.567  112.249 163.275 1.00 37.91  ? 430 PHE E CD1   1 
ATOM   13325 C CD2   . PHE F 2 448 ? 88.138  112.464 160.947 1.00 37.91  ? 430 PHE E CD2   1 
ATOM   13326 C CE1   . PHE F 2 448 ? 89.553  111.327 163.008 1.00 37.91  ? 430 PHE E CE1   1 
ATOM   13327 C CE2   . PHE F 2 448 ? 89.127  111.543 160.685 1.00 37.91  ? 430 PHE E CE2   1 
ATOM   13328 C CZ    . PHE F 2 448 ? 89.831  110.976 161.714 1.00 37.91  ? 430 PHE E CZ    1 
ATOM   13329 N N     . LEU F 2 449 ? 85.726  116.259 164.687 1.00 39.35  ? 431 LEU E N     1 
ATOM   13330 C CA    . LEU F 2 449 ? 84.883  117.419 164.929 1.00 39.35  ? 431 LEU E CA    1 
ATOM   13331 C C     . LEU F 2 449 ? 85.050  118.447 163.819 1.00 39.35  ? 431 LEU E C     1 
ATOM   13332 O O     . LEU F 2 449 ? 86.158  118.668 163.324 1.00 39.35  ? 431 LEU E O     1 
ATOM   13333 C CB    . LEU F 2 449 ? 85.230  118.062 166.274 1.00 39.35  ? 431 LEU E CB    1 
ATOM   13334 C CG    . LEU F 2 449 ? 84.578  117.461 167.519 1.00 39.35  ? 431 LEU E CG    1 
ATOM   13335 C CD1   . LEU F 2 449 ? 85.130  116.076 167.822 1.00 39.35  ? 431 LEU E CD1   1 
ATOM   13336 C CD2   . LEU F 2 449 ? 84.769  118.391 168.703 1.00 39.35  ? 431 LEU E CD2   1 
ATOM   13337 N N     . ASP F 2 450 ? 83.941  119.067 163.426 1.00 44.11  ? 432 ASP E N     1 
ATOM   13338 C CA    . ASP F 2 450 ? 84.025  120.271 162.606 1.00 44.11  ? 432 ASP E CA    1 
ATOM   13339 C C     . ASP F 2 450 ? 84.568  121.425 163.451 1.00 44.11  ? 432 ASP E C     1 
ATOM   13340 O O     . ASP F 2 450 ? 84.739  121.312 164.668 1.00 44.11  ? 432 ASP E O     1 
ATOM   13341 C CB    . ASP F 2 450 ? 82.667  120.647 161.989 1.00 44.11  ? 432 ASP E CB    1 
ATOM   13342 C CG    . ASP F 2 450 ? 81.532  120.689 162.999 1.00 44.11  ? 432 ASP E CG    1 
ATOM   13343 O OD1   . ASP F 2 450 ? 81.577  119.897 163.959 1.00 44.11  ? 432 ASP E OD1   1 
ATOM   13344 O OD2   . ASP F 2 450 ? 80.611  121.515 162.839 1.00 44.11  ? 432 ASP E OD2   1 
ATOM   13345 N N     . VAL F 2 451 ? 84.854  122.545 162.784 1.00 41.73  ? 433 VAL E N     1 
ATOM   13346 C CA    . VAL F 2 451 ? 85.529  123.662 163.442 1.00 41.73  ? 433 VAL E CA    1 
ATOM   13347 C C     . VAL F 2 451 ? 84.629  124.282 164.507 1.00 41.73  ? 433 VAL E C     1 
ATOM   13348 O O     . VAL F 2 451 ? 85.073  124.564 165.626 1.00 41.73  ? 433 VAL E O     1 
ATOM   13349 C CB    . VAL F 2 451 ? 85.974  124.707 162.399 1.00 41.73  ? 433 VAL E CB    1 
ATOM   13350 C CG1   . VAL F 2 451 ? 86.456  125.987 163.071 1.00 41.73  ? 433 VAL E CG1   1 
ATOM   13351 C CG2   . VAL F 2 451 ? 87.079  124.151 161.501 1.00 41.73  ? 433 VAL E CG2   1 
ATOM   13352 N N     . ARG F 2 452 ? 83.355  124.502 164.176 1.00 46.54  ? 434 ARG E N     1 
ATOM   13353 C CA    . ARG F 2 452 ? 82.469  125.210 165.095 1.00 46.54  ? 434 ARG E CA    1 
ATOM   13354 C C     . ARG F 2 452 ? 82.164  124.373 166.332 1.00 46.54  ? 434 ARG E C     1 
ATOM   13355 O O     . ARG F 2 452 ? 82.066  124.912 167.440 1.00 46.54  ? 434 ARG E O     1 
ATOM   13356 C CB    . ARG F 2 452 ? 81.180  125.608 164.374 1.00 46.54  ? 434 ARG E CB    1 
ATOM   13357 C CG    . ARG F 2 452 ? 80.052  126.084 165.301 1.00 46.54  ? 434 ARG E CG    1 
ATOM   13358 C CD    . ARG F 2 452 ? 79.015  126.979 164.611 1.00 46.54  ? 434 ARG E CD    1 
ATOM   13359 N NE    . ARG F 2 452 ? 78.858  126.711 163.184 1.00 46.54  ? 434 ARG E NE    1 
ATOM   13360 C CZ    . ARG F 2 452 ? 78.285  125.634 162.658 1.00 46.54  ? 434 ARG E CZ    1 
ATOM   13361 N NH1   . ARG F 2 452 ? 77.795  124.658 163.412 1.00 46.54  ? 434 ARG E NH1   1 
ATOM   13362 N NH2   . ARG F 2 452 ? 78.202  125.529 161.335 1.00 46.54  ? 434 ARG E NH2   1 
ATOM   13363 N N     . ARG F 2 453 ? 82.014  123.058 166.169 1.00 42.67  ? 435 ARG E N     1 
ATOM   13364 C CA    . ARG F 2 453 ? 81.701  122.200 167.308 1.00 42.67  ? 435 ARG E CA    1 
ATOM   13365 C C     . ARG F 2 453 ? 82.863  122.148 168.291 1.00 42.67  ? 435 ARG E C     1 
ATOM   13366 O O     . ARG F 2 453 ? 82.669  122.283 169.506 1.00 42.67  ? 435 ARG E O     1 
ATOM   13367 C CB    . ARG F 2 453 ? 81.347  120.800 166.814 1.00 42.67  ? 435 ARG E CB    1 
ATOM   13368 C CG    . ARG F 2 453 ? 80.937  119.825 167.903 1.00 42.67  ? 435 ARG E CG    1 
ATOM   13369 C CD    . ARG F 2 453 ? 79.966  118.769 167.380 1.00 42.67  ? 435 ARG E CD    1 
ATOM   13370 N NE    . ARG F 2 453 ? 80.360  118.236 166.075 1.00 42.67  ? 435 ARG E NE    1 
ATOM   13371 C CZ    . ARG F 2 453 ? 80.931  117.059 165.831 1.00 42.67  ? 435 ARG E CZ    1 
ATOM   13372 N NH1   . ARG F 2 453 ? 81.249  116.209 166.798 1.00 42.67  ? 435 ARG E NH1   1 
ATOM   13373 N NH2   . ARG F 2 453 ? 81.201  116.724 164.573 1.00 42.67  ? 435 ARG E NH2   1 
ATOM   13374 N N     . SER F 2 454 ? 84.082  121.960 167.779 1.00 41.11  ? 436 SER E N     1 
ATOM   13375 C CA    . SER F 2 454 ? 85.262  121.969 168.638 1.00 41.11  ? 436 SER E CA    1 
ATOM   13376 C C     . SER F 2 454 ? 85.460  123.332 169.285 1.00 41.11  ? 436 SER E C     1 
ATOM   13377 O O     . SER F 2 454 ? 85.848  123.420 170.458 1.00 41.11  ? 436 SER E O     1 
ATOM   13378 C CB    . SER F 2 454 ? 86.499  121.584 167.831 1.00 41.11  ? 436 SER E CB    1 
ATOM   13379 O OG    . SER F 2 454 ? 87.680  121.919 168.533 1.00 41.11  ? 436 SER E OG    1 
ATOM   13380 N N     . MET F 2 455 ? 85.197  124.404 168.533 1.00 45.72  ? 437 MET E N     1 
ATOM   13381 C CA    . MET F 2 455 ? 85.314  125.750 169.081 1.00 45.72  ? 437 MET E CA    1 
ATOM   13382 C C     . MET F 2 455 ? 84.336  125.963 170.228 1.00 45.72  ? 437 MET E C     1 
ATOM   13383 O O     . MET F 2 455 ? 84.705  126.516 171.264 1.00 45.72  ? 437 MET E O     1 
ATOM   13384 C CB    . MET F 2 455 ? 85.080  126.777 167.972 1.00 45.72  ? 437 MET E CB    1 
ATOM   13385 C CG    . MET F 2 455 ? 85.059  128.229 168.424 1.00 45.72  ? 437 MET E CG    1 
ATOM   13386 S SD    . MET F 2 455 ? 83.385  128.858 168.642 1.00 45.72  ? 437 MET E SD    1 
ATOM   13387 C CE    . MET F 2 455 ? 83.165  129.764 167.113 1.00 45.72  ? 437 MET E CE    1 
ATOM   13388 N N     . GLN F 2 456 ? 83.092  125.508 170.070 1.00 47.56  ? 438 GLN E N     1 
ATOM   13389 C CA    . GLN F 2 456 ? 82.107  125.648 171.138 1.00 47.56  ? 438 GLN E CA    1 
ATOM   13390 C C     . GLN F 2 456 ? 82.482  124.807 172.354 1.00 47.56  ? 438 GLN E C     1 
ATOM   13391 O O     . GLN F 2 456 ? 82.367  125.272 173.499 1.00 47.56  ? 438 GLN E O     1 
ATOM   13392 C CB    . GLN F 2 456 ? 80.724  125.259 170.612 1.00 47.56  ? 438 GLN E CB    1 
ATOM   13393 C CG    . GLN F 2 456 ? 79.543  125.749 171.455 1.00 47.56  ? 438 GLN E CG    1 
ATOM   13394 C CD    . GLN F 2 456 ? 79.170  124.811 172.594 1.00 47.56  ? 438 GLN E CD    1 
ATOM   13395 O OE1   . GLN F 2 456 ? 79.254  123.589 172.470 1.00 47.56  ? 438 GLN E OE1   1 
ATOM   13396 N NE2   . GLN F 2 456 ? 78.746  125.387 173.713 1.00 47.56  ? 438 GLN E NE2   1 
ATOM   13397 N N     . TYR F 2 457 ? 82.940  123.570 172.123 1.00 45.18  ? 439 TYR E N     1 
ATOM   13398 C CA    . TYR F 2 457 ? 83.310  122.691 173.229 1.00 45.18  ? 439 TYR E CA    1 
ATOM   13399 C C     . TYR F 2 457 ? 84.475  123.262 174.026 1.00 45.18  ? 439 TYR E C     1 
ATOM   13400 O O     . TYR F 2 457 ? 84.482  123.195 175.260 1.00 45.18  ? 439 TYR E O     1 
ATOM   13401 C CB    . TYR F 2 457 ? 83.671  121.296 172.708 1.00 45.18  ? 439 TYR E CB    1 
ATOM   13402 C CG    . TYR F 2 457 ? 82.511  120.325 172.586 1.00 45.18  ? 439 TYR E CG    1 
ATOM   13403 C CD1   . TYR F 2 457 ? 81.839  119.860 173.710 1.00 45.18  ? 439 TYR E CD1   1 
ATOM   13404 C CD2   . TYR F 2 457 ? 82.102  119.861 171.343 1.00 45.18  ? 439 TYR E CD2   1 
ATOM   13405 C CE1   . TYR F 2 457 ? 80.786  118.972 173.597 1.00 45.18  ? 439 TYR E CE1   1 
ATOM   13406 C CE2   . TYR F 2 457 ? 81.051  118.972 171.221 1.00 45.18  ? 439 TYR E CE2   1 
ATOM   13407 C CZ    . TYR F 2 457 ? 80.397  118.531 172.350 1.00 45.18  ? 439 TYR E CZ    1 
ATOM   13408 O OH    . TYR F 2 457 ? 79.351  117.645 172.233 1.00 45.18  ? 439 TYR E OH    1 
ATOM   13409 N N     . LEU F 2 458 ? 85.465  123.834 173.338 1.00 43.73  ? 440 LEU E N     1 
ATOM   13410 C CA    . LEU F 2 458 ? 86.604  124.427 174.029 1.00 43.73  ? 440 LEU E CA    1 
ATOM   13411 C C     . LEU F 2 458 ? 86.268  125.787 174.636 1.00 43.73  ? 440 LEU E C     1 
ATOM   13412 O O     . LEU F 2 458 ? 86.856  126.164 175.657 1.00 43.73  ? 440 LEU E O     1 
ATOM   13413 C CB    . LEU F 2 458 ? 87.779  124.542 173.057 1.00 43.73  ? 440 LEU E CB    1 
ATOM   13414 C CG    . LEU F 2 458 ? 89.204  124.769 173.572 1.00 43.73  ? 440 LEU E CG    1 
ATOM   13415 C CD1   . LEU F 2 458 ? 89.638  123.749 174.616 1.00 43.73  ? 440 LEU E CD1   1 
ATOM   13416 C CD2   . LEU F 2 458 ? 90.148  124.728 172.392 1.00 43.73  ? 440 LEU E CD2   1 
ATOM   13417 N N     . VAL F 2 459 ? 85.329  126.529 174.039 1.00 49.25  ? 441 VAL E N     1 
ATOM   13418 C CA    . VAL F 2 459 ? 84.883  127.787 174.629 1.00 49.25  ? 441 VAL E CA    1 
ATOM   13419 C C     . VAL F 2 459 ? 84.169  127.520 175.943 1.00 49.25  ? 441 VAL E C     1 
ATOM   13420 O O     . VAL F 2 459 ? 84.253  128.334 176.868 1.00 49.25  ? 441 VAL E O     1 
ATOM   13421 C CB    . VAL F 2 459 ? 83.993  128.565 173.634 1.00 49.25  ? 441 VAL E CB    1 
ATOM   13422 C CG1   . VAL F 2 459 ? 83.130  129.635 174.325 1.00 49.25  ? 441 VAL E CG1   1 
ATOM   13423 C CG2   . VAL F 2 459 ? 84.842  129.226 172.566 1.00 49.25  ? 441 VAL E CG2   1 
ATOM   13424 N N     . GLU F 2 460 ? 83.441  126.401 176.040 1.00 51.98  ? 442 GLU E N     1 
ATOM   13425 C CA    . GLU F 2 460 ? 82.794  126.044 177.302 1.00 51.98  ? 442 GLU E CA    1 
ATOM   13426 C C     . GLU F 2 460 ? 83.820  125.864 178.418 1.00 51.98  ? 442 GLU E C     1 
ATOM   13427 O O     . GLU F 2 460 ? 83.646  126.384 179.528 1.00 51.98  ? 442 GLU E O     1 
ATOM   13428 C CB    . GLU F 2 460 ? 81.971  124.768 177.128 1.00 51.98  ? 442 GLU E CB    1 
ATOM   13429 C CG    . GLU F 2 460 ? 80.612  124.983 176.479 1.00 51.98  ? 442 GLU E CG    1 
ATOM   13430 C CD    . GLU F 2 460 ? 79.733  123.744 176.523 1.00 51.98  ? 442 GLU E CD    1 
ATOM   13431 O OE1   . GLU F 2 460 ? 80.182  122.702 177.045 1.00 51.98  ? 442 GLU E OE1   1 
ATOM   13432 O OE2   . GLU F 2 460 ? 78.586  123.812 176.034 1.00 51.98  ? 442 GLU E OE2   1 
ATOM   13433 N N     . TYR F 2 461 ? 84.913  125.152 178.130 1.00 48.01  ? 443 TYR E N     1 
ATOM   13434 C CA    . TYR F 2 461 ? 85.970  124.981 179.123 1.00 48.01  ? 443 TYR E CA    1 
ATOM   13435 C C     . TYR F 2 461 ? 86.635  126.311 179.453 1.00 48.01  ? 443 TYR E C     1 
ATOM   13436 O O     . TYR F 2 461 ? 86.860  126.631 180.626 1.00 48.01  ? 443 TYR E O     1 
ATOM   13437 C CB    . TYR F 2 461 ? 87.016  123.976 178.627 1.00 48.01  ? 443 TYR E CB    1 
ATOM   13438 C CG    . TYR F 2 461 ? 88.400  124.216 179.199 1.00 48.01  ? 443 TYR E CG    1 
ATOM   13439 C CD1   . TYR F 2 461 ? 88.701  123.862 180.507 1.00 48.01  ? 443 TYR E CD1   1 
ATOM   13440 C CD2   . TYR F 2 461 ? 89.406  124.789 178.428 1.00 48.01  ? 443 TYR E CD2   1 
ATOM   13441 C CE1   . TYR F 2 461 ? 89.957  124.083 181.034 1.00 48.01  ? 443 TYR E CE1   1 
ATOM   13442 C CE2   . TYR F 2 461 ? 90.662  125.014 178.949 1.00 48.01  ? 443 TYR E CE2   1 
ATOM   13443 C CZ    . TYR F 2 461 ? 90.933  124.657 180.250 1.00 48.01  ? 443 TYR E CZ    1 
ATOM   13444 O OH    . TYR F 2 461 ? 92.186  124.877 180.771 1.00 48.01  ? 443 TYR E OH    1 
ATOM   13445 N N     . GLN F 2 462 ? 86.971  127.096 178.424 1.00 52.15  ? 444 GLN E N     1 
ATOM   13446 C CA    . GLN F 2 462 ? 87.721  128.326 178.654 1.00 52.15  ? 444 GLN E CA    1 
ATOM   13447 C C     . GLN F 2 462 ? 86.889  129.362 179.400 1.00 52.15  ? 444 GLN E C     1 
ATOM   13448 O O     . GLN F 2 462 ? 87.445  130.174 180.148 1.00 52.15  ? 444 GLN E O     1 
ATOM   13449 C CB    . GLN F 2 462 ? 88.215  128.895 177.322 1.00 52.15  ? 444 GLN E CB    1 
ATOM   13450 C CG    . GLN F 2 462 ? 89.458  129.779 177.429 1.00 52.15  ? 444 GLN E CG    1 
ATOM   13451 C CD    . GLN F 2 462 ? 90.725  128.997 177.739 1.00 52.15  ? 444 GLN E CD    1 
ATOM   13452 O OE1   . GLN F 2 462 ? 90.828  127.812 177.430 1.00 52.15  ? 444 GLN E OE1   1 
ATOM   13453 N NE2   . GLN F 2 462 ? 91.695  129.663 178.353 1.00 52.15  ? 444 GLN E NE2   1 
ATOM   13454 N N     . SER F 2 463 ? 85.567  129.351 179.214 1.00 58.55  ? 445 SER E N     1 
ATOM   13455 C CA    . SER F 2 463 ? 84.697  130.200 180.020 1.00 58.55  ? 445 SER E CA    1 
ATOM   13456 C C     . SER F 2 463 ? 84.560  129.655 181.434 1.00 58.55  ? 445 SER E C     1 
ATOM   13457 O O     . SER F 2 463 ? 84.516  130.426 182.399 1.00 58.55  ? 445 SER E O     1 
ATOM   13458 C CB    . SER F 2 463 ? 83.323  130.323 179.363 1.00 58.55  ? 445 SER E CB    1 
ATOM   13459 O OG    . SER F 2 463 ? 82.344  130.713 180.310 1.00 58.55  ? 445 SER E OG    1 
ATOM   13460 N N     . GLN F 2 464 ? 84.477  128.329 181.577 1.00 60.39  ? 446 GLN E N     1 
ATOM   13461 C CA    . GLN F 2 464 ? 84.394  127.736 182.908 1.00 60.39  ? 446 GLN E CA    1 
ATOM   13462 C C     . GLN F 2 464 ? 85.678  127.983 183.694 1.00 60.39  ? 446 GLN E C     1 
ATOM   13463 O O     . GLN F 2 464 ? 85.635  128.365 184.869 1.00 60.39  ? 446 GLN E O     1 
ATOM   13464 C CB    . GLN F 2 464 ? 84.103  126.238 182.793 1.00 60.39  ? 446 GLN E CB    1 
ATOM   13465 C CG    . GLN F 2 464 ? 84.031  125.498 184.125 1.00 60.39  ? 446 GLN E CG    1 
ATOM   13466 C CD    . GLN F 2 464 ? 85.329  124.790 184.478 1.00 60.39  ? 446 GLN E CD    1 
ATOM   13467 O OE1   . GLN F 2 464 ? 85.773  123.893 183.762 1.00 60.39  ? 446 GLN E OE1   1 
ATOM   13468 N NE2   . GLN F 2 464 ? 85.944  125.192 185.585 1.00 60.39  ? 446 GLN E NE2   1 
ATOM   13469 N N     . TYR F 2 465 ? 86.830  127.780 183.051 1.00 60.89  ? 447 TYR E N     1 
ATOM   13470 C CA    . TYR F 2 465 ? 88.139  127.995 183.673 1.00 60.89  ? 447 TYR E CA    1 
ATOM   13471 C C     . TYR F 2 465 ? 88.539  129.437 183.365 1.00 60.89  ? 447 TYR E C     1 
ATOM   13472 O O     . TYR F 2 465 ? 89.212  129.742 182.379 1.00 60.89  ? 447 TYR E O     1 
ATOM   13473 C CB    . TYR F 2 465 ? 89.140  126.959 183.158 1.00 60.89  ? 447 TYR E CB    1 
ATOM   13474 C CG    . TYR F 2 465 ? 90.562  127.016 183.709 1.00 60.89  ? 447 TYR E CG    1 
ATOM   13475 C CD1   . TYR F 2 465 ? 91.497  127.939 183.244 1.00 60.89  ? 447 TYR E CD1   1 
ATOM   13476 C CD2   . TYR F 2 465 ? 90.966  126.130 184.699 1.00 60.89  ? 447 TYR E CD2   1 
ATOM   13477 C CE1   . TYR F 2 465 ? 92.781  127.977 183.749 1.00 60.89  ? 447 TYR E CE1   1 
ATOM   13478 C CE2   . TYR F 2 465 ? 92.251  126.161 185.210 1.00 60.89  ? 447 TYR E CE2   1 
ATOM   13479 C CZ    . TYR F 2 465 ? 93.154  127.087 184.731 1.00 60.89  ? 447 TYR E CZ    1 
ATOM   13480 O OH    . TYR F 2 465 ? 94.434  127.124 185.235 1.00 60.89  ? 447 TYR E OH    1 
ATOM   13481 N N     . MET F 2 466 ? 88.059  130.348 184.207 1.00 70.43  ? 448 MET E N     1 
ATOM   13482 C CA    . MET F 2 466 ? 88.380  131.770 184.079 1.00 70.43  ? 448 MET E CA    1 
ATOM   13483 C C     . MET F 2 466 ? 87.978  132.517 185.347 1.00 70.43  ? 448 MET E C     1 
ATOM   13484 O O     . MET F 2 466 ? 88.664  133.442 185.782 1.00 70.43  ? 448 MET E O     1 
ATOM   13485 C CB    . MET F 2 466 ? 87.678  132.399 182.867 1.00 70.43  ? 448 MET E CB    1 
ATOM   13486 C CG    . MET F 2 466 ? 88.468  133.556 182.243 1.00 70.43  ? 448 MET E CG    1 
ATOM   13487 S SD    . MET F 2 466 ? 87.713  134.497 180.881 1.00 70.43  ? 448 MET E SD    1 
ATOM   13488 C CE    . MET F 2 466 ? 85.959  134.523 181.253 1.00 70.43  ? 448 MET E CE    1 
ATOM   13489 N N     . SER G 3 377 ? 85.579  182.664 208.640 1.00 112.76 ? 347 SER G N     1 
ATOM   13490 C CA    . SER G 3 377 ? 84.688  181.558 208.188 1.00 112.76 ? 347 SER G CA    1 
ATOM   13491 C C     . SER G 3 377 ? 85.313  180.811 207.014 1.00 112.76 ? 347 SER G C     1 
ATOM   13492 O O     . SER G 3 377 ? 85.414  179.585 207.029 1.00 112.76 ? 347 SER G O     1 
ATOM   13493 C CB    . SER G 3 377 ? 83.313  182.102 207.796 1.00 112.76 ? 347 SER G CB    1 
ATOM   13494 O OG    . SER G 3 377 ? 83.411  182.996 206.702 1.00 112.76 ? 347 SER G OG    1 
ATOM   13495 N N     . LYS G 3 378 ? 85.730  181.563 205.992 1.00 111.56 ? 348 LYS G N     1 
ATOM   13496 C CA    . LYS G 3 378 ? 86.373  180.955 204.833 1.00 111.56 ? 348 LYS G CA    1 
ATOM   13497 C C     . LYS G 3 378 ? 87.788  180.469 205.132 1.00 111.56 ? 348 LYS G C     1 
ATOM   13498 O O     . LYS G 3 378 ? 88.320  179.658 204.368 1.00 111.56 ? 348 LYS G O     1 
ATOM   13499 C CB    . LYS G 3 378 ? 86.392  181.945 203.664 1.00 111.56 ? 348 LYS G CB    1 
ATOM   13500 C CG    . LYS G 3 378 ? 87.275  183.171 203.865 1.00 111.56 ? 348 LYS G CG    1 
ATOM   13501 C CD    . LYS G 3 378 ? 86.995  184.223 202.805 1.00 111.56 ? 348 LYS G CD    1 
ATOM   13502 C CE    . LYS G 3 378 ? 87.899  185.433 202.965 1.00 111.56 ? 348 LYS G CE    1 
ATOM   13503 N NZ    . LYS G 3 378 ? 87.632  186.471 201.931 1.00 111.56 ? 348 LYS G NZ    1 
ATOM   13504 N N     . ASN G 3 379 ? 88.412  180.950 206.213 1.00 109.03 ? 349 ASN G N     1 
ATOM   13505 C CA    . ASN G 3 379 ? 89.736  180.458 206.581 1.00 109.03 ? 349 ASN G CA    1 
ATOM   13506 C C     . ASN G 3 379 ? 89.685  179.054 207.182 1.00 109.03 ? 349 ASN G C     1 
ATOM   13507 O O     . ASN G 3 379 ? 90.663  178.307 207.063 1.00 109.03 ? 349 ASN G O     1 
ATOM   13508 C CB    . ASN G 3 379 ? 90.402  181.426 207.561 1.00 109.03 ? 349 ASN G CB    1 
ATOM   13509 C CG    . ASN G 3 379 ? 89.678  181.503 208.894 1.00 109.03 ? 349 ASN G CG    1 
ATOM   13510 O OD1   . ASN G 3 379 ? 88.513  181.895 208.956 1.00 109.03 ? 349 ASN G OD1   1 
ATOM   13511 N ND2   . ASN G 3 379 ? 90.368  181.133 209.969 1.00 109.03 ? 349 ASN G ND2   1 
ATOM   13512 N N     . ILE G 3 380 ? 88.564  178.677 207.807 1.00 107.33 ? 350 ILE G N     1 
ATOM   13513 C CA    . ILE G 3 380 ? 88.397  177.389 208.486 1.00 107.33 ? 350 ILE G CA    1 
ATOM   13514 C C     . ILE G 3 380 ? 87.365  176.589 207.697 1.00 107.33 ? 350 ILE G C     1 
ATOM   13515 O O     . ILE G 3 380 ? 86.153  176.774 207.857 1.00 107.33 ? 350 ILE G O     1 
ATOM   13516 C CB    . ILE G 3 380 ? 88.001  177.544 209.964 1.00 107.33 ? 350 ILE G CB    1 
ATOM   13517 C CG1   . ILE G 3 380 ? 86.911  178.608 210.194 1.00 107.33 ? 350 ILE G CG1   1 
ATOM   13518 C CG2   . ILE G 3 380 ? 89.231  177.865 210.803 1.00 107.33 ? 350 ILE G CG2   1 
ATOM   13519 C CD1   . ILE G 3 380 ? 85.977  178.284 211.340 1.00 107.33 ? 350 ILE G CD1   1 
ATOM   13520 N N     . LYS G 3 381 ? 87.854  175.688 206.846 1.00 106.55 ? 351 LYS G N     1 
ATOM   13521 C CA    . LYS G 3 381 ? 87.047  174.850 205.969 1.00 106.55 ? 351 LYS G CA    1 
ATOM   13522 C C     . LYS G 3 381 ? 87.387  173.383 206.200 1.00 106.55 ? 351 LYS G C     1 
ATOM   13523 O O     . LYS G 3 381 ? 88.342  173.040 206.900 1.00 106.55 ? 351 LYS G O     1 
ATOM   13524 C CB    . LYS G 3 381 ? 87.276  175.222 204.496 1.00 106.55 ? 351 LYS G CB    1 
ATOM   13525 C CG    . LYS G 3 381 ? 86.892  176.660 204.120 1.00 106.55 ? 351 LYS G CG    1 
ATOM   13526 C CD    . LYS G 3 381 ? 85.438  177.049 204.443 1.00 106.55 ? 351 LYS G CD    1 
ATOM   13527 C CE    . LYS G 3 381 ? 84.400  176.090 203.863 1.00 106.55 ? 351 LYS G CE    1 
ATOM   13528 N NZ    . LYS G 3 381 ? 84.598  175.844 202.408 1.00 106.55 ? 351 LYS G NZ    1 
ATOM   13529 N N     . THR G 3 382 ? 86.582  172.520 205.598 1.00 104.28 ? 352 THR G N     1 
ATOM   13530 C CA    . THR G 3 382 ? 86.776  171.082 205.723 1.00 104.28 ? 352 THR G CA    1 
ATOM   13531 C C     . THR G 3 382 ? 88.054  170.671 204.993 1.00 104.28 ? 352 THR G C     1 
ATOM   13532 O O     . THR G 3 382 ? 88.168  170.949 203.791 1.00 104.28 ? 352 THR G O     1 
ATOM   13533 C CB    . THR G 3 382 ? 85.584  170.340 205.126 1.00 104.28 ? 352 THR G CB    1 
ATOM   13534 O OG1   . THR G 3 382 ? 85.238  170.926 203.865 1.00 104.28 ? 352 THR G OG1   1 
ATOM   13535 C CG2   . THR G 3 382 ? 84.385  170.400 206.060 1.00 104.28 ? 352 THR G CG2   1 
ATOM   13536 N N     . PRO G 3 383 ? 89.033  170.022 205.640 1.00 89.74  ? 353 PRO G N     1 
ATOM   13537 C CA    . PRO G 3 383 ? 90.123  169.420 204.863 1.00 89.74  ? 353 PRO G CA    1 
ATOM   13538 C C     . PRO G 3 383 ? 89.667  168.143 204.178 1.00 89.74  ? 353 PRO G C     1 
ATOM   13539 O O     . PRO G 3 383 ? 88.952  167.323 204.760 1.00 89.74  ? 353 PRO G O     1 
ATOM   13540 C CB    . PRO G 3 383 ? 91.199  169.135 205.916 1.00 89.74  ? 353 PRO G CB    1 
ATOM   13541 C CG    . PRO G 3 383 ? 90.460  168.948 207.160 1.00 89.74  ? 353 PRO G CG    1 
ATOM   13542 C CD    . PRO G 3 383 ? 89.289  169.879 207.088 1.00 89.74  ? 353 PRO G CD    1 
ATOM   13543 N N     . LYS G 3 384 ? 90.081  167.989 202.922 1.00 81.78  ? 354 LYS G N     1 
ATOM   13544 C CA    . LYS G 3 384 ? 89.811  166.787 202.144 1.00 81.78  ? 354 LYS G CA    1 
ATOM   13545 C C     . LYS G 3 384 ? 90.857  165.694 202.336 1.00 81.78  ? 354 LYS G C     1 
ATOM   13546 O O     . LYS G 3 384 ? 90.606  164.550 201.941 1.00 81.78  ? 354 LYS G O     1 
ATOM   13547 C CB    . LYS G 3 384 ? 89.724  167.143 200.654 1.00 81.78  ? 354 LYS G CB    1 
ATOM   13548 C CG    . LYS G 3 384 ? 89.084  166.070 199.781 1.00 81.78  ? 354 LYS G CG    1 
ATOM   13549 C CD    . LYS G 3 384 ? 88.832  166.575 198.370 1.00 81.78  ? 354 LYS G CD    1 
ATOM   13550 C CE    . LYS G 3 384 ? 87.378  166.959 198.161 1.00 81.78  ? 354 LYS G CE    1 
ATOM   13551 N NZ    . LYS G 3 384 ? 87.189  167.766 196.925 1.00 81.78  ? 354 LYS G NZ    1 
ATOM   13552 N N     . SER G 3 385 ? 92.005  165.999 202.941 1.00 73.21  ? 355 SER G N     1 
ATOM   13553 C CA    . SER G 3 385 ? 93.127  165.071 202.955 1.00 73.21  ? 355 SER G CA    1 
ATOM   13554 C C     . SER G 3 385 ? 94.071  165.440 204.090 1.00 73.21  ? 355 SER G C     1 
ATOM   13555 O O     . SER G 3 385 ? 93.971  166.514 204.686 1.00 73.21  ? 355 SER G O     1 
ATOM   13556 C CB    . SER G 3 385 ? 93.859  165.087 201.612 1.00 73.21  ? 355 SER G CB    1 
ATOM   13557 O OG    . SER G 3 385 ? 93.060  164.535 200.581 1.00 73.21  ? 355 SER G OG    1 
ATOM   13558 N N     . ALA G 3 386 ? 94.999  164.521 204.381 1.00 69.43  ? 356 ALA G N     1 
ATOM   13559 C CA    . ALA G 3 386 ? 96.025  164.789 205.384 1.00 69.43  ? 356 ALA G CA    1 
ATOM   13560 C C     . ALA G 3 386 ? 96.935  165.931 204.959 1.00 69.43  ? 356 ALA G C     1 
ATOM   13561 O O     . ALA G 3 386 ? 97.475  166.643 205.814 1.00 69.43  ? 356 ALA G O     1 
ATOM   13562 C CB    . ALA G 3 386 ? 96.850  163.529 205.644 1.00 69.43  ? 356 ALA G CB    1 
ATOM   13563 N N     . TYR G 3 387 ? 97.134  166.104 203.650 1.00 61.44  ? 357 TYR G N     1 
ATOM   13564 C CA    . TYR G 3 387 ? 97.825  167.283 203.137 1.00 61.44  ? 357 TYR G CA    1 
ATOM   13565 C C     . TYR G 3 387 ? 97.103  168.557 203.557 1.00 61.44  ? 357 TYR G C     1 
ATOM   13566 O O     . TYR G 3 387 ? 97.723  169.501 204.066 1.00 61.44  ? 357 TYR G O     1 
ATOM   13567 C CB    . TYR G 3 387 ? 97.915  167.181 201.612 1.00 61.44  ? 357 TYR G CB    1 
ATOM   13568 C CG    . TYR G 3 387 ? 98.617  168.322 200.915 1.00 61.44  ? 357 TYR G CG    1 
ATOM   13569 C CD1   . TYR G 3 387 ? 99.984  168.293 200.714 1.00 61.44  ? 357 TYR G CD1   1 
ATOM   13570 C CD2   . TYR G 3 387 ? 97.906  169.403 200.413 1.00 61.44  ? 357 TYR G CD2   1 
ATOM   13571 C CE1   . TYR G 3 387 ? 100.636 169.324 200.068 1.00 61.44  ? 357 TYR G CE1   1 
ATOM   13572 C CE2   . TYR G 3 387 ? 98.547  170.438 199.761 1.00 61.44  ? 357 TYR G CE2   1 
ATOM   13573 C CZ    . TYR G 3 387 ? 99.911  170.389 199.585 1.00 61.44  ? 357 TYR G CZ    1 
ATOM   13574 O OH    . TYR G 3 387 ? 100.551 171.419 198.938 1.00 61.44  ? 357 TYR G OH    1 
ATOM   13575 N N     . GLU G 3 388 ? 95.780  168.580 203.383 1.00 74.75  ? 358 GLU G N     1 
ATOM   13576 C CA    . GLU G 3 388 ? 94.998  169.755 203.751 1.00 74.75  ? 358 GLU G CA    1 
ATOM   13577 C C     . GLU G 3 388 ? 95.019  169.973 205.257 1.00 74.75  ? 358 GLU G C     1 
ATOM   13578 O O     . GLU G 3 388 ? 95.133  171.115 205.721 1.00 74.75  ? 358 GLU G O     1 
ATOM   13579 C CB    . GLU G 3 388 ? 93.552  169.613 203.264 1.00 74.75  ? 358 GLU G CB    1 
ATOM   13580 C CG    . GLU G 3 388 ? 93.377  169.236 201.793 1.00 74.75  ? 358 GLU G CG    1 
ATOM   13581 C CD    . GLU G 3 388 ? 94.038  170.202 200.839 1.00 74.75  ? 358 GLU G CD    1 
ATOM   13582 O OE1   . GLU G 3 388 ? 94.268  171.369 201.221 1.00 74.75  ? 358 GLU G OE1   1 
ATOM   13583 O OE2   . GLU G 3 388 ? 94.332  169.785 199.701 1.00 74.75  ? 358 GLU G OE2   1 
ATOM   13584 N N     . PHE G 3 389 ? 94.920  168.888 206.032 1.00 78.82  ? 359 PHE G N     1 
ATOM   13585 C CA    . PHE G 3 389 ? 94.939  169.004 207.487 1.00 78.82  ? 359 PHE G CA    1 
ATOM   13586 C C     . PHE G 3 389 ? 96.272  169.558 207.968 1.00 78.82  ? 359 PHE G C     1 
ATOM   13587 O O     . PHE G 3 389 ? 96.313  170.451 208.819 1.00 78.82  ? 359 PHE G O     1 
ATOM   13588 C CB    . PHE G 3 389 ? 94.661  167.642 208.132 1.00 78.82  ? 359 PHE G CB    1 
ATOM   13589 C CG    . PHE G 3 389 ? 94.898  167.610 209.623 1.00 78.82  ? 359 PHE G CG    1 
ATOM   13590 C CD1   . PHE G 3 389 ? 93.935  168.091 210.493 1.00 78.82  ? 359 PHE G CD1   1 
ATOM   13591 C CD2   . PHE G 3 389 ? 96.071  167.088 210.156 1.00 78.82  ? 359 PHE G CD2   1 
ATOM   13592 C CE1   . PHE G 3 389 ? 94.140  168.066 211.858 1.00 78.82  ? 359 PHE G CE1   1 
ATOM   13593 C CE2   . PHE G 3 389 ? 96.283  167.072 211.521 1.00 78.82  ? 359 PHE G CE2   1 
ATOM   13594 C CZ    . PHE G 3 389 ? 95.313  167.553 212.371 1.00 78.82  ? 359 PHE G CZ    1 
ATOM   13595 N N     . GLU G 3 390 ? 97.378  169.037 207.431 1.00 73.02  ? 360 GLU G N     1 
ATOM   13596 C CA    . GLU G 3 390 ? 98.691  169.478 207.888 1.00 73.02  ? 360 GLU G CA    1 
ATOM   13597 C C     . GLU G 3 390 ? 98.972  170.914 207.464 1.00 73.02  ? 360 GLU G C     1 
ATOM   13598 O O     . GLU G 3 390 ? 99.576  171.681 208.224 1.00 73.02  ? 360 GLU G O     1 
ATOM   13599 C CB    . GLU G 3 390 ? 99.774  168.528 207.362 1.00 73.02  ? 360 GLU G CB    1 
ATOM   13600 C CG    . GLU G 3 390 ? 101.268 168.932 207.555 1.00 73.02  ? 360 GLU G CG    1 
ATOM   13601 C CD    . GLU G 3 390 ? 101.688 169.446 208.941 1.00 73.02  ? 360 GLU G CD    1 
ATOM   13602 O OE1   . GLU G 3 390 ? 102.887 169.767 209.086 1.00 73.02  ? 360 GLU G OE1   1 
ATOM   13603 O OE2   . GLU G 3 390 ? 100.893 169.482 209.898 1.00 73.02  ? 360 GLU G OE2   1 
ATOM   13604 N N     . ASN G 3 391 ? 98.532  171.308 206.265 1.00 69.40  ? 361 ASN G N     1 
ATOM   13605 C CA    . ASN G 3 391 ? 98.740  172.686 205.834 1.00 69.40  ? 361 ASN G CA    1 
ATOM   13606 C C     . ASN G 3 391 ? 97.825  173.667 206.555 1.00 69.40  ? 361 ASN G C     1 
ATOM   13607 O O     . ASN G 3 391 ? 98.178  174.846 206.670 1.00 69.40  ? 361 ASN G O     1 
ATOM   13608 C CB    . ASN G 3 391 ? 98.552  172.797 204.325 1.00 69.40  ? 361 ASN G CB    1 
ATOM   13609 C CG    . ASN G 3 391 ? 99.653  172.104 203.560 1.00 69.40  ? 361 ASN G CG    1 
ATOM   13610 O OD1   . ASN G 3 391 ? 100.500 171.428 204.143 1.00 69.40  ? 361 ASN G OD1   1 
ATOM   13611 N ND2   . ASN G 3 391 ? 99.662  172.282 202.251 1.00 69.40  ? 361 ASN G ND2   1 
ATOM   13612 N N     . SER G 3 392 ? 96.664  173.217 207.037 1.00 82.68  ? 362 SER G N     1 
ATOM   13613 C CA    . SER G 3 392 ? 95.867  174.054 207.930 1.00 82.68  ? 362 SER G CA    1 
ATOM   13614 C C     . SER G 3 392 ? 96.503  174.134 209.312 1.00 82.68  ? 362 SER G C     1 
ATOM   13615 O O     . SER G 3 392 ? 96.457  175.183 209.965 1.00 82.68  ? 362 SER G O     1 
ATOM   13616 C CB    . SER G 3 392 ? 94.443  173.509 208.028 1.00 82.68  ? 362 SER G CB    1 
ATOM   13617 O OG    . SER G 3 392 ? 94.377  172.417 208.929 1.00 82.68  ? 362 SER G OG    1 
ATOM   13618 N N     . TRP G 3 393 ? 97.095  173.030 209.774 1.00 85.45  ? 363 TRP G N     1 
ATOM   13619 C CA    . TRP G 3 393 ? 97.739  173.006 211.084 1.00 85.45  ? 363 TRP G CA    1 
ATOM   13620 C C     . TRP G 3 393 ? 98.951  173.929 211.118 1.00 85.45  ? 363 TRP G C     1 
ATOM   13621 O O     . TRP G 3 393 ? 99.196  174.603 212.125 1.00 85.45  ? 363 TRP G O     1 
ATOM   13622 C CB    . TRP G 3 393 ? 98.156  171.574 211.434 1.00 85.45  ? 363 TRP G CB    1 
ATOM   13623 C CG    . TRP G 3 393 ? 98.060  171.224 212.885 1.00 85.45  ? 363 TRP G CG    1 
ATOM   13624 C CD1   . TRP G 3 393 ? 99.085  170.868 213.711 1.00 85.45  ? 363 TRP G CD1   1 
ATOM   13625 C CD2   . TRP G 3 393 ? 96.868  171.161 213.676 1.00 85.45  ? 363 TRP G CD2   1 
ATOM   13626 N NE1   . TRP G 3 393 ? 98.609  170.602 214.970 1.00 85.45  ? 363 TRP G NE1   1 
ATOM   13627 C CE2   . TRP G 3 393 ? 97.250  170.775 214.975 1.00 85.45  ? 363 TRP G CE2   1 
ATOM   13628 C CE3   . TRP G 3 393 ? 95.517  171.401 213.414 1.00 85.45  ? 363 TRP G CE3   1 
ATOM   13629 C CZ2   . TRP G 3 393 ? 96.330  170.621 216.008 1.00 85.45  ? 363 TRP G CZ2   1 
ATOM   13630 C CZ3   . TRP G 3 393 ? 94.606  171.251 214.441 1.00 85.45  ? 363 TRP G CZ3   1 
ATOM   13631 C CH2   . TRP G 3 393 ? 95.016  170.867 215.723 1.00 85.45  ? 363 TRP G CH2   1 
ATOM   13632 N N     . ARG G 3 394 ? 99.728  173.952 210.033 1.00 66.55  ? 364 ARG G N     1 
ATOM   13633 C CA    . ARG G 3 394 ? 100.923 174.796 209.985 1.00 66.55  ? 364 ARG G CA    1 
ATOM   13634 C C     . ARG G 3 394 ? 100.559 176.275 210.035 1.00 66.55  ? 364 ARG G C     1 
ATOM   13635 O O     . ARG G 3 394 ? 101.188 177.056 210.757 1.00 66.55  ? 364 ARG G O     1 
ATOM   13636 C CB    . ARG G 3 394 ? 101.744 174.505 208.724 1.00 66.55  ? 364 ARG G CB    1 
ATOM   13637 C CG    . ARG G 3 394 ? 102.997 173.675 208.969 1.00 66.55  ? 364 ARG G CG    1 
ATOM   13638 C CD    . ARG G 3 394 ? 103.789 173.466 207.684 1.00 66.55  ? 364 ARG G CD    1 
ATOM   13639 N NE    . ARG G 3 394 ? 104.332 174.719 207.157 1.00 66.55  ? 364 ARG G NE    1 
ATOM   13640 C CZ    . ARG G 3 394 ? 105.586 175.152 207.265 1.00 66.55  ? 364 ARG G CZ    1 
ATOM   13641 N NH1   . ARG G 3 394 ? 106.512 174.486 207.941 1.00 66.55  ? 364 ARG G NH1   1 
ATOM   13642 N NH2   . ARG G 3 394 ? 105.921 176.302 206.687 1.00 66.55  ? 364 ARG G NH2   1 
ATOM   13643 N N     . SER G 3 395 ? 99.551  176.680 209.259 1.00 81.79  ? 365 SER G N     1 
ATOM   13644 C CA    . SER G 3 395 ? 99.165  178.088 209.221 1.00 81.79  ? 365 SER G CA    1 
ATOM   13645 C C     . SER G 3 395 ? 98.575  178.534 210.552 1.00 81.79  ? 365 SER G C     1 
ATOM   13646 O O     . SER G 3 395 ? 98.843  179.650 211.014 1.00 81.79  ? 365 SER G O     1 
ATOM   13647 C CB    . SER G 3 395 ? 98.170  178.324 208.084 1.00 81.79  ? 365 SER G CB    1 
ATOM   13648 O OG    . SER G 3 395 ? 97.541  179.588 208.203 1.00 81.79  ? 365 SER G OG    1 
ATOM   13649 N N     . PHE G 3 396 ? 97.776  177.672 211.182 1.00 94.67  ? 366 PHE G N     1 
ATOM   13650 C CA    . PHE G 3 396 ? 97.132  177.947 212.463 1.00 94.67  ? 366 PHE G CA    1 
ATOM   13651 C C     . PHE G 3 396 ? 97.960  177.449 213.648 1.00 94.67  ? 366 PHE G C     1 
ATOM   13652 O O     . PHE G 3 396 ? 97.412  177.272 214.741 1.00 94.67  ? 366 PHE G O     1 
ATOM   13653 C CB    . PHE G 3 396 ? 95.723  177.318 212.522 1.00 94.67  ? 366 PHE G CB    1 
ATOM   13654 C CG    . PHE G 3 396 ? 94.734  177.757 211.427 1.00 94.67  ? 366 PHE G CG    1 
ATOM   13655 C CD1   . PHE G 3 396 ? 94.966  178.818 210.549 1.00 94.67  ? 366 PHE G CD1   1 
ATOM   13656 C CD2   . PHE G 3 396 ? 93.544  177.058 211.288 1.00 94.67  ? 366 PHE G CD2   1 
ATOM   13657 C CE1   . PHE G 3 396 ? 94.040  179.165 209.584 1.00 94.67  ? 366 PHE G CE1   1 
ATOM   13658 C CE2   . PHE G 3 396 ? 92.617  177.405 210.321 1.00 94.67  ? 366 PHE G CE2   1 
ATOM   13659 C CZ    . PHE G 3 396 ? 92.867  178.457 209.471 1.00 94.67  ? 366 PHE G CZ    1 
ATOM   13660 N N     . SER G 3 397 ? 99.266  177.237 213.461 1.00 90.60  ? 367 SER G N     1 
ATOM   13661 C CA    . SER G 3 397 ? 100.067 176.572 214.486 1.00 90.60  ? 367 SER G CA    1 
ATOM   13662 C C     . SER G 3 397 ? 100.225 177.441 215.728 1.00 90.60  ? 367 SER G C     1 
ATOM   13663 O O     . SER G 3 397 ? 100.051 176.965 216.856 1.00 90.60  ? 367 SER G O     1 
ATOM   13664 C CB    . SER G 3 397 ? 101.436 176.204 213.914 1.00 90.60  ? 367 SER G CB    1 
ATOM   13665 O OG    . SER G 3 397 ? 102.316 175.771 214.936 1.00 90.60  ? 367 SER G OG    1 
ATOM   13666 N N     . GLY G 3 398 ? 100.547 178.723 215.542 1.00 98.02  ? 368 GLY G N     1 
ATOM   13667 C CA    . GLY G 3 398 ? 100.823 179.583 216.679 1.00 98.02  ? 368 GLY G CA    1 
ATOM   13668 C C     . GLY G 3 398 ? 99.608  180.004 217.478 1.00 98.02  ? 368 GLY G C     1 
ATOM   13669 O O     . GLY G 3 398 ? 99.756  180.358 218.652 1.00 98.02  ? 368 GLY G O     1 
ATOM   13670 N N     . ASP G 3 399 ? 98.412  179.957 216.879 1.00 104.31 ? 369 ASP G N     1 
ATOM   13671 C CA    . ASP G 3 399 ? 97.174  180.432 217.495 1.00 104.31 ? 369 ASP G CA    1 
ATOM   13672 C C     . ASP G 3 399 ? 96.292  179.225 217.794 1.00 104.31 ? 369 ASP G C     1 
ATOM   13673 O O     . ASP G 3 399 ? 95.797  178.566 216.873 1.00 104.31 ? 369 ASP G O     1 
ATOM   13674 C CB    . ASP G 3 399 ? 96.473  181.434 216.577 1.00 104.31 ? 369 ASP G CB    1 
ATOM   13675 C CG    . ASP G 3 399 ? 94.997  181.594 216.889 1.00 104.31 ? 369 ASP G CG    1 
ATOM   13676 O OD1   . ASP G 3 399 ? 94.182  180.791 216.389 1.00 104.31 ? 369 ASP G OD1   1 
ATOM   13677 O OD2   . ASP G 3 399 ? 94.650  182.529 217.642 1.00 104.31 ? 369 ASP G OD2   1 
ATOM   13678 N N     . SER G 3 400 ? 96.093  178.945 219.084 1.00 104.36 ? 370 SER G N     1 
ATOM   13679 C CA    . SER G 3 400 ? 95.291  177.793 219.483 1.00 104.36 ? 370 SER G CA    1 
ATOM   13680 C C     . SER G 3 400 ? 93.806  177.991 219.195 1.00 104.36 ? 370 SER G C     1 
ATOM   13681 O O     . SER G 3 400 ? 93.078  177.003 219.037 1.00 104.36 ? 370 SER G O     1 
ATOM   13682 C CB    . SER G 3 400 ? 95.499  177.505 220.970 1.00 104.36 ? 370 SER G CB    1 
ATOM   13683 O OG    . SER G 3 400 ? 94.837  176.314 221.357 1.00 104.36 ? 370 SER G OG    1 
ATOM   13684 N N     . ALA G 3 401 ? 93.339  179.246 219.135 1.00 104.84 ? 371 ALA G N     1 
ATOM   13685 C CA    . ALA G 3 401 ? 91.910  179.515 218.982 1.00 104.84 ? 371 ALA G CA    1 
ATOM   13686 C C     . ALA G 3 401 ? 91.376  178.988 217.656 1.00 104.84 ? 371 ALA G C     1 
ATOM   13687 O O     . ALA G 3 401 ? 90.294  178.392 217.609 1.00 104.84 ? 371 ALA G O     1 
ATOM   13688 C CB    . ALA G 3 401 ? 91.646  181.015 219.103 1.00 104.84 ? 371 ALA G CB    1 
ATOM   13689 N N     . LEU G 3 402 ? 92.129  179.177 216.576 1.00 103.43 ? 372 LEU G N     1 
ATOM   13690 C CA    . LEU G 3 402 ? 91.780  178.617 215.276 1.00 103.43 ? 372 LEU G CA    1 
ATOM   13691 C C     . LEU G 3 402 ? 92.147  177.138 215.137 1.00 103.43 ? 372 LEU G C     1 
ATOM   13692 O O     . LEU G 3 402 ? 91.934  176.578 214.056 1.00 103.43 ? 372 LEU G O     1 
ATOM   13693 C CB    . LEU G 3 402 ? 92.456  179.423 214.162 1.00 103.43 ? 372 LEU G CB    1 
ATOM   13694 C CG    . LEU G 3 402 ? 92.073  180.903 214.039 1.00 103.43 ? 372 LEU G CG    1 
ATOM   13695 C CD1   . LEU G 3 402 ? 92.969  181.594 213.024 1.00 103.43 ? 372 LEU G CD1   1 
ATOM   13696 C CD2   . LEU G 3 402 ? 90.610  181.070 213.646 1.00 103.43 ? 372 LEU G CD2   1 
ATOM   13697 N N     . ARG G 3 403 ? 92.687  176.503 216.184 1.00 99.41  ? 373 ARG G N     1 
ATOM   13698 C CA    . ARG G 3 403 ? 92.904  175.061 216.240 1.00 99.41  ? 373 ARG G CA    1 
ATOM   13699 C C     . ARG G 3 403 ? 91.841  174.347 217.055 1.00 99.41  ? 373 ARG G C     1 
ATOM   13700 O O     . ARG G 3 403 ? 91.419  173.250 216.687 1.00 99.41  ? 373 ARG G O     1 
ATOM   13701 C CB    . ARG G 3 403 ? 94.283  174.765 216.840 1.00 99.41  ? 373 ARG G CB    1 
ATOM   13702 C CG    . ARG G 3 403 ? 95.428  175.017 215.877 1.00 99.41  ? 373 ARG G CG    1 
ATOM   13703 C CD    . ARG G 3 403 ? 96.754  174.427 216.347 1.00 99.41  ? 373 ARG G CD    1 
ATOM   13704 N NE    . ARG G 3 403 ? 97.073  174.757 217.736 1.00 99.41  ? 373 ARG G NE    1 
ATOM   13705 C CZ    . ARG G 3 403 ? 96.855  173.993 218.804 1.00 99.41  ? 373 ARG G CZ    1 
ATOM   13706 N NH1   . ARG G 3 403 ? 96.240  172.820 218.722 1.00 99.41  ? 373 ARG G NH1   1 
ATOM   13707 N NH2   . ARG G 3 403 ? 97.259  174.422 219.996 1.00 99.41  ? 373 ARG G NH2   1 
ATOM   13708 N N     . SER G 3 404 ? 91.393  174.956 218.155 1.00 105.74 ? 374 SER G N     1 
ATOM   13709 C CA    . SER G 3 404 ? 90.318  174.370 218.946 1.00 105.74 ? 374 SER G CA    1 
ATOM   13710 C C     . SER G 3 404 ? 88.996  174.401 218.193 1.00 105.74 ? 374 SER G C     1 
ATOM   13711 O O     . SER G 3 404 ? 88.177  173.487 218.344 1.00 105.74 ? 374 SER G O     1 
ATOM   13712 C CB    . SER G 3 404 ? 90.201  175.102 220.282 1.00 105.74 ? 374 SER G CB    1 
ATOM   13713 O OG    . SER G 3 404 ? 91.462  175.185 220.924 1.00 105.74 ? 374 SER G OG    1 
ATOM   13714 N N     . GLN G 3 405 ? 88.767  175.432 217.381 1.00 105.07 ? 375 GLN G N     1 
ATOM   13715 C CA    . GLN G 3 405 ? 87.578  175.487 216.544 1.00 105.07 ? 375 GLN G CA    1 
ATOM   13716 C C     . GLN G 3 405 ? 87.766  174.804 215.193 1.00 105.07 ? 375 GLN G C     1 
ATOM   13717 O O     . GLN G 3 405 ? 86.789  174.669 214.449 1.00 105.07 ? 375 GLN G O     1 
ATOM   13718 C CB    . GLN G 3 405 ? 87.146  176.940 216.322 1.00 105.07 ? 375 GLN G CB    1 
ATOM   13719 C CG    . GLN G 3 405 ? 88.140  177.778 215.540 1.00 105.07 ? 375 GLN G CG    1 
ATOM   13720 C CD    . GLN G 3 405 ? 87.908  179.264 215.720 1.00 105.07 ? 375 GLN G CD    1 
ATOM   13721 O OE1   . GLN G 3 405 ? 88.112  179.810 216.804 1.00 105.07 ? 375 GLN G OE1   1 
ATOM   13722 N NE2   . GLN G 3 405 ? 87.474  179.928 214.656 1.00 105.07 ? 375 GLN G NE2   1 
ATOM   13723 N N     . LEU G 3 406 ? 88.987  174.378 214.853 1.00 101.07 ? 376 LEU G N     1 
ATOM   13724 C CA    . LEU G 3 406 ? 89.190  173.639 213.609 1.00 101.07 ? 376 LEU G CA    1 
ATOM   13725 C C     . LEU G 3 406 ? 88.490  172.287 213.664 1.00 101.07 ? 376 LEU G C     1 
ATOM   13726 O O     . LEU G 3 406 ? 87.729  171.933 212.754 1.00 101.07 ? 376 LEU G O     1 
ATOM   13727 C CB    . LEU G 3 406 ? 90.687  173.467 213.339 1.00 101.07 ? 376 LEU G CB    1 
ATOM   13728 C CG    . LEU G 3 406 ? 91.125  172.596 212.153 1.00 101.07 ? 376 LEU G CG    1 
ATOM   13729 C CD1   . LEU G 3 406 ? 90.389  172.964 210.872 1.00 101.07 ? 376 LEU G CD1   1 
ATOM   13730 C CD2   . LEU G 3 406 ? 92.626  172.721 211.944 1.00 101.07 ? 376 LEU G CD2   1 
ATOM   13731 N N     . LEU G 3 407 ? 88.665  171.553 214.771 1.00 101.42 ? 377 LEU G N     1 
ATOM   13732 C CA    . LEU G 3 407 ? 88.034  170.243 214.930 1.00 101.42 ? 377 LEU G CA    1 
ATOM   13733 C C     . LEU G 3 407 ? 86.503  170.232 214.857 1.00 101.42 ? 377 LEU G C     1 
ATOM   13734 O O     . LEU G 3 407 ? 85.918  169.157 214.682 1.00 101.42 ? 377 LEU G O     1 
ATOM   13735 C CB    . LEU G 3 407 ? 88.581  169.454 216.148 1.00 101.42 ? 377 LEU G CB    1 
ATOM   13736 C CG    . LEU G 3 407 ? 90.052  169.037 216.064 1.00 101.42 ? 377 LEU G CG    1 
ATOM   13737 C CD1   . LEU G 3 407 ? 90.888  169.835 217.052 1.00 101.42 ? 377 LEU G CD1   1 
ATOM   13738 C CD2   . LEU G 3 407 ? 90.222  167.543 216.314 1.00 101.42 ? 377 LEU G CD2   1 
ATOM   13739 N N     . LYS G 3 408 ? 85.843  171.394 214.970 1.00 105.84 ? 378 LYS G N     1 
ATOM   13740 C CA    . LYS G 3 408 ? 84.393  171.446 214.860 1.00 105.84 ? 378 LYS G CA    1 
ATOM   13741 C C     . LYS G 3 408 ? 83.936  171.398 213.407 1.00 105.84 ? 378 LYS G C     1 
ATOM   13742 O O     . LYS G 3 408 ? 82.844  170.885 213.134 1.00 105.84 ? 378 LYS G O     1 
ATOM   13743 C CB    . LYS G 3 408 ? 83.838  172.707 215.538 1.00 105.84 ? 378 LYS G CB    1 
ATOM   13744 C CG    . LYS G 3 408 ? 84.536  173.163 216.838 1.00 105.84 ? 378 LYS G CG    1 
ATOM   13745 C CD    . LYS G 3 408 ? 84.749  172.063 217.897 1.00 105.84 ? 378 LYS G CD    1 
ATOM   13746 C CE    . LYS G 3 408 ? 83.477  171.317 218.285 1.00 105.84 ? 378 LYS G CE    1 
ATOM   13747 N NZ    . LYS G 3 408 ? 83.773  170.290 219.321 1.00 105.84 ? 378 LYS G NZ    1 
ATOM   13748 N N     . VAL G 3 409 ? 84.747  171.900 212.462 1.00 105.32 ? 379 VAL G N     1 
ATOM   13749 C CA    . VAL G 3 409 ? 84.293  171.978 211.070 1.00 105.32 ? 379 VAL G CA    1 
ATOM   13750 C C     . VAL G 3 409 ? 84.488  170.681 210.298 1.00 105.32 ? 379 VAL G C     1 
ATOM   13751 O O     . VAL G 3 409 ? 84.225  170.665 209.088 1.00 105.32 ? 379 VAL G O     1 
ATOM   13752 C CB    . VAL G 3 409 ? 84.986  173.125 210.298 1.00 105.32 ? 379 VAL G CB    1 
ATOM   13753 C CG1   . VAL G 3 409 ? 84.992  174.402 211.129 1.00 105.32 ? 379 VAL G CG1   1 
ATOM   13754 C CG2   . VAL G 3 409 ? 86.404  172.760 209.813 1.00 105.32 ? 379 VAL G CG2   1 
ATOM   13755 N N     . THR G 3 410 ? 84.935  169.600 210.951 1.00 103.28 ? 380 THR G N     1 
ATOM   13756 C CA    . THR G 3 410 ? 85.239  168.329 210.308 1.00 103.28 ? 380 THR G CA    1 
ATOM   13757 C C     . THR G 3 410 ? 84.555  167.209 211.076 1.00 103.28 ? 380 THR G C     1 
ATOM   13758 O O     . THR G 3 410 ? 84.440  167.260 212.304 1.00 103.28 ? 380 THR G O     1 
ATOM   13759 C CB    . THR G 3 410 ? 86.754  168.074 210.265 1.00 103.28 ? 380 THR G CB    1 
ATOM   13760 O OG1   . THR G 3 410 ? 87.424  169.250 209.798 1.00 103.28 ? 380 THR G OG1   1 
ATOM   13761 C CG2   . THR G 3 410 ? 87.090  166.902 209.343 1.00 103.28 ? 380 THR G CG2   1 
ATOM   13762 N N     . THR G 3 411 ? 84.116  166.192 210.340 1.00 101.38 ? 381 THR G N     1 
ATOM   13763 C CA    . THR G 3 411 ? 83.451  165.049 210.964 1.00 101.38 ? 381 THR G CA    1 
ATOM   13764 C C     . THR G 3 411 ? 84.509  164.078 211.489 1.00 101.38 ? 381 THR G C     1 
ATOM   13765 O O     . THR G 3 411 ? 85.446  163.753 210.753 1.00 101.38 ? 381 THR G O     1 
ATOM   13766 C CB    . THR G 3 411 ? 82.531  164.310 209.983 1.00 101.38 ? 381 THR G CB    1 
ATOM   13767 O OG1   . THR G 3 411 ? 83.289  163.341 209.247 1.00 101.38 ? 381 THR G OG1   1 
ATOM   13768 C CG2   . THR G 3 411 ? 81.811  165.267 209.027 1.00 101.38 ? 381 THR G CG2   1 
ATOM   13769 N N     . PRO G 3 412 ? 84.418  163.599 212.741 1.00 98.87  ? 382 PRO G N     1 
ATOM   13770 C CA    . PRO G 3 412 ? 85.395  162.588 213.182 1.00 98.87  ? 382 PRO G CA    1 
ATOM   13771 C C     . PRO G 3 412 ? 85.292  161.271 212.433 1.00 98.87  ? 382 PRO G C     1 
ATOM   13772 O O     . PRO G 3 412 ? 86.281  160.532 212.389 1.00 98.87  ? 382 PRO G O     1 
ATOM   13773 C CB    . PRO G 3 412 ? 85.070  162.409 214.669 1.00 98.87  ? 382 PRO G CB    1 
ATOM   13774 C CG    . PRO G 3 412 ? 83.668  162.788 214.784 1.00 98.87  ? 382 PRO G CG    1 
ATOM   13775 C CD    . PRO G 3 412 ? 83.498  163.929 213.847 1.00 98.87  ? 382 PRO G CD    1 
ATOM   13776 N N     . SER G 3 413 ? 84.137  160.953 211.842 1.00 98.41  ? 383 SER G N     1 
ATOM   13777 C CA    . SER G 3 413 ? 84.017  159.728 211.059 1.00 98.41  ? 383 SER G CA    1 
ATOM   13778 C C     . SER G 3 413 ? 84.926  159.756 209.837 1.00 98.41  ? 383 SER G C     1 
ATOM   13779 O O     . SER G 3 413 ? 85.459  158.716 209.436 1.00 98.41  ? 383 SER G O     1 
ATOM   13780 C CB    . SER G 3 413 ? 82.564  159.516 210.632 1.00 98.41  ? 383 SER G CB    1 
ATOM   13781 O OG    . SER G 3 413 ? 82.198  160.418 209.602 1.00 98.41  ? 383 SER G OG    1 
ATOM   13782 N N     . SER G 3 414 ? 85.116  160.932 209.239 1.00 95.03  ? 384 SER G N     1 
ATOM   13783 C CA    . SER G 3 414 ? 86.033  161.074 208.114 1.00 95.03  ? 384 SER G CA    1 
ATOM   13784 C C     . SER G 3 414 ? 87.502  161.040 208.523 1.00 95.03  ? 384 SER G C     1 
ATOM   13785 O O     . SER G 3 414 ? 88.356  160.963 207.635 1.00 95.03  ? 384 SER G O     1 
ATOM   13786 C CB    . SER G 3 414 ? 85.746  162.384 207.376 1.00 95.03  ? 384 SER G CB    1 
ATOM   13787 O OG    . SER G 3 414 ? 86.482  162.461 206.168 1.00 95.03  ? 384 SER G OG    1 
ATOM   13788 N N     . LEU G 3 415 ? 87.814  161.097 209.824 1.00 89.13  ? 385 LEU G N     1 
ATOM   13789 C CA    . LEU G 3 415 ? 89.204  161.204 210.269 1.00 89.13  ? 385 LEU G CA    1 
ATOM   13790 C C     . LEU G 3 415 ? 90.075  160.021 209.851 1.00 89.13  ? 385 LEU G C     1 
ATOM   13791 O O     . LEU G 3 415 ? 91.181  160.261 209.337 1.00 89.13  ? 385 LEU G O     1 
ATOM   13792 C CB    . LEU G 3 415 ? 89.231  161.417 211.788 1.00 89.13  ? 385 LEU G CB    1 
ATOM   13793 C CG    . LEU G 3 415 ? 90.598  161.532 212.466 1.00 89.13  ? 385 LEU G CG    1 
ATOM   13794 C CD1   . LEU G 3 415 ? 90.614  162.700 213.447 1.00 89.13  ? 385 LEU G CD1   1 
ATOM   13795 C CD2   . LEU G 3 415 ? 90.971  160.237 213.170 1.00 89.13  ? 385 LEU G CD2   1 
ATOM   13796 N N     . PRO G 3 416 ? 89.674  158.750 210.018 1.00 86.28  ? 386 PRO G N     1 
ATOM   13797 C CA    . PRO G 3 416 ? 90.521  157.667 209.483 1.00 86.28  ? 386 PRO G CA    1 
ATOM   13798 C C     . PRO G 3 416 ? 90.618  157.647 207.965 1.00 86.28  ? 386 PRO G C     1 
ATOM   13799 O O     . PRO G 3 416 ? 91.534  157.001 207.439 1.00 86.28  ? 386 PRO G O     1 
ATOM   13800 C CB    . PRO G 3 416 ? 89.859  156.391 210.021 1.00 86.28  ? 386 PRO G CB    1 
ATOM   13801 C CG    . PRO G 3 416 ? 88.493  156.782 210.378 1.00 86.28  ? 386 PRO G CG    1 
ATOM   13802 C CD    . PRO G 3 416 ? 88.582  158.196 210.842 1.00 86.28  ? 386 PRO G CD    1 
ATOM   13803 N N     . GLN G 3 417 ? 89.702  158.303 207.245 1.00 83.27  ? 387 GLN G N     1 
ATOM   13804 C CA    . GLN G 3 417 ? 89.877  158.507 205.810 1.00 83.27  ? 387 GLN G CA    1 
ATOM   13805 C C     . GLN G 3 417 ? 90.838  159.654 205.517 1.00 83.27  ? 387 GLN G C     1 
ATOM   13806 O O     . GLN G 3 417 ? 91.580  159.594 204.530 1.00 83.27  ? 387 GLN G O     1 
ATOM   13807 C CB    . GLN G 3 417 ? 88.525  158.769 205.144 1.00 83.27  ? 387 GLN G CB    1 
ATOM   13808 C CG    . GLN G 3 417 ? 88.591  158.895 203.613 1.00 83.27  ? 387 GLN G CG    1 
ATOM   13809 C CD    . GLN G 3 417 ? 88.662  160.333 203.100 1.00 83.27  ? 387 GLN G CD    1 
ATOM   13810 O OE1   . GLN G 3 417 ? 88.872  161.279 203.860 1.00 83.27  ? 387 GLN G OE1   1 
ATOM   13811 N NE2   . GLN G 3 417 ? 88.490  160.494 201.794 1.00 83.27  ? 387 GLN G NE2   1 
ATOM   13812 N N     . ILE G 3 418 ? 90.828  160.703 206.344 1.00 80.18  ? 388 ILE G N     1 
ATOM   13813 C CA    . ILE G 3 418 ? 91.745  161.825 206.146 1.00 80.18  ? 388 ILE G CA    1 
ATOM   13814 C C     . ILE G 3 418 ? 93.183  161.364 206.349 1.00 80.18  ? 388 ILE G C     1 
ATOM   13815 O O     . ILE G 3 418 ? 94.052  161.591 205.499 1.00 80.18  ? 388 ILE G O     1 
ATOM   13816 C CB    . ILE G 3 418 ? 91.376  162.985 207.098 1.00 80.18  ? 388 ILE G CB    1 
ATOM   13817 C CG1   . ILE G 3 418 ? 90.075  163.702 206.670 1.00 80.18  ? 388 ILE G CG1   1 
ATOM   13818 C CG2   . ILE G 3 418 ? 92.523  164.014 207.229 1.00 80.18  ? 388 ILE G CG2   1 
ATOM   13819 C CD1   . ILE G 3 418 ? 90.055  164.372 205.293 1.00 80.18  ? 388 ILE G CD1   1 
ATOM   13820 N N     . PHE G 3 419 ? 93.446  160.697 207.471 1.00 77.11  ? 389 PHE G N     1 
ATOM   13821 C CA    . PHE G 3 419 ? 94.767  160.167 207.788 1.00 77.11  ? 389 PHE G CA    1 
ATOM   13822 C C     . PHE G 3 419 ? 94.861  158.745 207.252 1.00 77.11  ? 389 PHE G C     1 
ATOM   13823 O O     . PHE G 3 419 ? 94.095  157.869 207.667 1.00 77.11  ? 389 PHE G O     1 
ATOM   13824 C CB    . PHE G 3 419 ? 95.025  160.188 209.294 1.00 77.11  ? 389 PHE G CB    1 
ATOM   13825 C CG    . PHE G 3 419 ? 94.929  161.553 209.918 1.00 77.11  ? 389 PHE G CG    1 
ATOM   13826 C CD1   . PHE G 3 419 ? 93.712  162.054 210.337 1.00 77.11  ? 389 PHE G CD1   1 
ATOM   13827 C CD2   . PHE G 3 419 ? 96.059  162.326 210.100 1.00 77.11  ? 389 PHE G CD2   1 
ATOM   13828 C CE1   . PHE G 3 419 ? 93.618  163.296 210.913 1.00 77.11  ? 389 PHE G CE1   1 
ATOM   13829 C CE2   . PHE G 3 419 ? 95.970  163.575 210.679 1.00 77.11  ? 389 PHE G CE2   1 
ATOM   13830 C CZ    . PHE G 3 419 ? 94.744  164.055 211.086 1.00 77.11  ? 389 PHE G CZ    1 
ATOM   13831 N N     . LYS G 3 420 ? 95.814  158.521 206.348 1.00 67.80  ? 390 LYS G N     1 
ATOM   13832 C CA    . LYS G 3 420 ? 96.019  157.248 205.657 1.00 67.80  ? 390 LYS G CA    1 
ATOM   13833 C C     . LYS G 3 420 ? 97.474  156.831 205.887 1.00 67.80  ? 390 LYS G C     1 
ATOM   13834 O O     . LYS G 3 420 ? 98.255  156.604 204.964 1.00 67.80  ? 390 LYS G O     1 
ATOM   13835 C CB    . LYS G 3 420 ? 95.653  157.317 204.164 1.00 67.80  ? 390 LYS G CB    1 
ATOM   13836 C CG    . LYS G 3 420 ? 94.461  158.208 203.799 1.00 67.80  ? 390 LYS G CG    1 
ATOM   13837 C CD    . LYS G 3 420 ? 94.247  158.220 202.292 1.00 67.80  ? 390 LYS G CD    1 
ATOM   13838 C CE    . LYS G 3 420 ? 93.063  159.087 201.897 1.00 67.80  ? 390 LYS G CE    1 
ATOM   13839 N NZ    . LYS G 3 420 ? 92.944  159.227 200.421 1.00 67.80  ? 390 LYS G NZ    1 
ATOM   13840 N N     . ASN G 3 421 ? 97.833  156.757 207.174 1.00 64.99  ? 391 ASN G N     1 
ATOM   13841 C CA    . ASN G 3 421 ? 99.158  156.598 207.813 1.00 64.99  ? 391 ASN G CA    1 
ATOM   13842 C C     . ASN G 3 421 ? 99.951  157.901 207.922 1.00 64.99  ? 391 ASN G C     1 
ATOM   13843 O O     . ASN G 3 421 ? 101.047 157.862 208.494 1.00 64.99  ? 391 ASN G O     1 
ATOM   13844 C CB    . ASN G 3 421 ? 100.121 155.562 207.186 1.00 64.99  ? 391 ASN G CB    1 
ATOM   13845 C CG    . ASN G 3 421 ? 99.436  154.370 206.513 1.00 64.99  ? 391 ASN G CG    1 
ATOM   13846 O OD1   . ASN G 3 421 ? 98.835  153.527 207.173 1.00 64.99  ? 391 ASN G OD1   1 
ATOM   13847 N ND2   . ASN G 3 421 ? 99.533  154.305 205.189 1.00 64.99  ? 391 ASN G ND2   1 
ATOM   13848 N N     . ALA G 3 422 ? 99.453  159.039 207.431 1.00 65.03  ? 392 ALA G N     1 
ATOM   13849 C CA    . ALA G 3 422 ? 100.159 160.320 207.564 1.00 65.03  ? 392 ALA G CA    1 
ATOM   13850 C C     . ALA G 3 422 ? 99.765  160.993 208.879 1.00 65.03  ? 392 ALA G C     1 
ATOM   13851 O O     . ALA G 3 422 ? 99.065  162.006 208.917 1.00 65.03  ? 392 ALA G O     1 
ATOM   13852 C CB    . ALA G 3 422 ? 99.866  161.220 206.371 1.00 65.03  ? 392 ALA G CB    1 
ATOM   13853 N N     . LEU G 3 423 ? 100.244 160.405 209.974 1.00 72.96  ? 393 LEU G N     1 
ATOM   13854 C CA    . LEU G 3 423 ? 100.005 160.943 211.311 1.00 72.96  ? 393 LEU G CA    1 
ATOM   13855 C C     . LEU G 3 423 ? 101.197 160.589 212.186 1.00 72.96  ? 393 LEU G C     1 
ATOM   13856 O O     . LEU G 3 423 ? 101.462 159.406 212.419 1.00 72.96  ? 393 LEU G O     1 
ATOM   13857 C CB    . LEU G 3 423 ? 98.705  160.388 211.904 1.00 72.96  ? 393 LEU G CB    1 
ATOM   13858 C CG    . LEU G 3 423 ? 97.937  161.274 212.897 1.00 72.96  ? 393 LEU G CG    1 
ATOM   13859 C CD1   . LEU G 3 423 ? 96.587  160.652 213.234 1.00 72.96  ? 393 LEU G CD1   1 
ATOM   13860 C CD2   . LEU G 3 423 ? 98.734  161.535 214.165 1.00 72.96  ? 393 LEU G CD2   1 
ATOM   13861 N N     . THR G 3 424 ? 101.911 161.611 212.652 1.00 71.13  ? 394 THR G N     1 
ATOM   13862 C CA    . THR G 3 424 ? 103.058 161.463 213.538 1.00 71.13  ? 394 THR G CA    1 
ATOM   13863 C C     . THR G 3 424 ? 102.640 161.660 214.992 1.00 71.13  ? 394 THR G C     1 
ATOM   13864 O O     . THR G 3 424 ? 101.578 162.212 215.288 1.00 71.13  ? 394 THR G O     1 
ATOM   13865 C CB    . THR G 3 424 ? 104.168 162.454 213.168 1.00 71.13  ? 394 THR G CB    1 
ATOM   13866 O OG1   . THR G 3 424 ? 105.376 162.095 213.851 1.00 71.13  ? 394 THR G OG1   1 
ATOM   13867 C CG2   . THR G 3 424 ? 103.790 163.892 213.531 1.00 71.13  ? 394 THR G CG2   1 
ATOM   13868 N N     . SER G 3 425 ? 103.497 161.187 215.899 1.00 75.93  ? 395 SER G N     1 
ATOM   13869 C CA    . SER G 3 425 ? 103.163 161.204 217.323 1.00 75.93  ? 395 SER G CA    1 
ATOM   13870 C C     . SER G 3 425 ? 102.974 162.607 217.892 1.00 75.93  ? 395 SER G C     1 
ATOM   13871 O O     . SER G 3 425 ? 102.052 162.786 218.709 1.00 75.93  ? 395 SER G O     1 
ATOM   13872 C CB    . SER G 3 425 ? 104.232 160.445 218.122 1.00 75.93  ? 395 SER G CB    1 
ATOM   13873 O OG    . SER G 3 425 ? 104.342 160.965 219.436 1.00 75.93  ? 395 SER G OG    1 
ATOM   13874 N N     . PRO G 3 426 ? 103.813 163.604 217.573 1.00 73.32  ? 396 PRO G N     1 
ATOM   13875 C CA    . PRO G 3 426 ? 103.495 164.981 217.994 1.00 73.32  ? 396 PRO G CA    1 
ATOM   13876 C C     . PRO G 3 426 ? 102.144 165.484 217.513 1.00 73.32  ? 396 PRO G C     1 
ATOM   13877 O O     . PRO G 3 426 ? 101.444 166.162 218.275 1.00 73.32  ? 396 PRO G O     1 
ATOM   13878 C CB    . PRO G 3 426 ? 104.646 165.790 217.387 1.00 73.32  ? 396 PRO G CB    1 
ATOM   13879 C CG    . PRO G 3 426 ? 105.791 164.861 217.427 1.00 73.32  ? 396 PRO G CG    1 
ATOM   13880 C CD    . PRO G 3 426 ? 105.228 163.483 217.173 1.00 73.32  ? 396 PRO G CD    1 
ATOM   13881 N N     . VAL G 3 427 ? 101.743 165.159 216.282 1.00 78.40  ? 397 VAL G N     1 
ATOM   13882 C CA    . VAL G 3 427 ? 100.427 165.580 215.808 1.00 78.40  ? 397 VAL G CA    1 
ATOM   13883 C C     . VAL G 3 427 ? 99.332  164.851 216.577 1.00 78.40  ? 397 VAL G C     1 
ATOM   13884 O O     . VAL G 3 427 ? 98.267  165.418 216.847 1.00 78.40  ? 397 VAL G O     1 
ATOM   13885 C CB    . VAL G 3 427 ? 100.303 165.369 214.284 1.00 78.40  ? 397 VAL G CB    1 
ATOM   13886 C CG1   . VAL G 3 427 ? 98.840  165.482 213.809 1.00 78.40  ? 397 VAL G CG1   1 
ATOM   13887 C CG2   . VAL G 3 427 ? 101.182 166.376 213.529 1.00 78.40  ? 397 VAL G CG2   1 
ATOM   13888 N N     . LEU G 3 428 ? 99.568  163.585 216.933 1.00 83.65  ? 398 LEU G N     1 
ATOM   13889 C CA    . LEU G 3 428 ? 98.599  162.840 217.732 1.00 83.65  ? 398 LEU G CA    1 
ATOM   13890 C C     . LEU G 3 428 ? 98.415  163.478 219.104 1.00 83.65  ? 398 LEU G C     1 
ATOM   13891 O O     . LEU G 3 428 ? 97.282  163.660 219.572 1.00 83.65  ? 398 LEU G O     1 
ATOM   13892 C CB    . LEU G 3 428 ? 99.057  161.386 217.873 1.00 83.65  ? 398 LEU G CB    1 
ATOM   13893 C CG    . LEU G 3 428 ? 98.220  160.417 218.717 1.00 83.65  ? 398 LEU G CG    1 
ATOM   13894 C CD1   . LEU G 3 428 ? 96.754  160.432 218.309 1.00 83.65  ? 398 LEU G CD1   1 
ATOM   13895 C CD2   . LEU G 3 428 ? 98.789  159.009 218.624 1.00 83.65  ? 398 LEU G CD2   1 
ATOM   13896 N N     . VAL G 3 429 ? 99.526  163.837 219.755 1.00 86.14  ? 399 VAL G N     1 
ATOM   13897 C CA    . VAL G 3 429 ? 99.459  164.482 221.066 1.00 86.14  ? 399 VAL G CA    1 
ATOM   13898 C C     . VAL G 3 429 ? 98.770  165.834 220.953 1.00 86.14  ? 399 VAL G C     1 
ATOM   13899 O O     . VAL G 3 429 ? 97.951  166.203 221.805 1.00 86.14  ? 399 VAL G O     1 
ATOM   13900 C CB    . VAL G 3 429 ? 100.872 164.610 221.676 1.00 86.14  ? 399 VAL G CB    1 
ATOM   13901 C CG1   . VAL G 3 429 ? 100.861 165.501 222.939 1.00 86.14  ? 399 VAL G CG1   1 
ATOM   13902 C CG2   . VAL G 3 429 ? 101.458 163.220 221.994 1.00 86.14  ? 399 VAL G CG2   1 
ATOM   13903 N N     . ASP G 3 430 ? 99.090  166.590 219.897 1.00 87.63  ? 400 ASP G N     1 
ATOM   13904 C CA    . ASP G 3 430 ? 98.466  167.892 219.685 1.00 87.63  ? 400 ASP G CA    1 
ATOM   13905 C C     . ASP G 3 430 ? 96.963  167.761 219.484 1.00 87.63  ? 400 ASP G C     1 
ATOM   13906 O O     . ASP G 3 430 ? 96.190  168.539 220.048 1.00 87.63  ? 400 ASP G O     1 
ATOM   13907 C CB    . ASP G 3 430 ? 99.095  168.589 218.475 1.00 87.63  ? 400 ASP G CB    1 
ATOM   13908 C CG    . ASP G 3 430 ? 100.358 169.365 218.823 1.00 87.63  ? 400 ASP G CG    1 
ATOM   13909 O OD1   . ASP G 3 430 ? 100.386 170.074 219.853 1.00 87.63  ? 400 ASP G OD1   1 
ATOM   13910 O OD2   . ASP G 3 430 ? 101.336 169.266 218.051 1.00 87.63  ? 400 ASP G OD2   1 
ATOM   13911 N N     . ILE G 3 431 ? 96.529  166.774 218.696 1.00 90.98  ? 401 ILE G N     1 
ATOM   13912 C CA    . ILE G 3 431 ? 95.107  166.650 218.392 1.00 90.98  ? 401 ILE G CA    1 
ATOM   13913 C C     . ILE G 3 431 ? 94.352  166.175 219.630 1.00 90.98  ? 401 ILE G C     1 
ATOM   13914 O O     . ILE G 3 431 ? 93.223  166.612 219.885 1.00 90.98  ? 401 ILE G O     1 
ATOM   13915 C CB    . ILE G 3 431 ? 94.908  165.716 217.171 1.00 90.98  ? 401 ILE G CB    1 
ATOM   13916 C CG1   . ILE G 3 431 ? 94.963  166.495 215.841 1.00 90.98  ? 401 ILE G CG1   1 
ATOM   13917 C CG2   . ILE G 3 431 ? 93.536  164.983 217.183 1.00 90.98  ? 401 ILE G CG2   1 
ATOM   13918 C CD1   . ILE G 3 431 ? 93.827  167.490 215.536 1.00 90.98  ? 401 ILE G CD1   1 
ATOM   13919 N N     . ILE G 3 432 ? 94.953  165.267 220.412 1.00 94.22  ? 402 ILE G N     1 
ATOM   13920 C CA    . ILE G 3 432 ? 94.325  164.831 221.662 1.00 94.22  ? 402 ILE G CA    1 
ATOM   13921 C C     . ILE G 3 432 ? 94.196  166.005 222.625 1.00 94.22  ? 402 ILE G C     1 
ATOM   13922 O O     . ILE G 3 432 ? 93.153  166.193 223.265 1.00 94.22  ? 402 ILE G O     1 
ATOM   13923 C CB    . ILE G 3 432 ? 95.116  163.670 222.303 1.00 94.22  ? 402 ILE G CB    1 
ATOM   13924 C CG1   . ILE G 3 432 ? 95.093  162.404 221.435 1.00 94.22  ? 402 ILE G CG1   1 
ATOM   13925 C CG2   . ILE G 3 432 ? 94.559  163.339 223.696 1.00 94.22  ? 402 ILE G CG2   1 
ATOM   13926 C CD1   . ILE G 3 432 ? 96.290  161.490 221.673 1.00 94.22  ? 402 ILE G CD1   1 
ATOM   13927 N N     . LYS G 3 433 ? 95.254  166.813 222.742 1.00 94.37  ? 403 LYS G N     1 
ATOM   13928 C CA    . LYS G 3 433 ? 95.209  167.979 223.617 1.00 94.37  ? 403 LYS G CA    1 
ATOM   13929 C C     . LYS G 3 433 ? 94.197  169.007 223.130 1.00 94.37  ? 403 LYS G C     1 
ATOM   13930 O O     . LYS G 3 433 ? 93.579  169.703 223.943 1.00 94.37  ? 403 LYS G O     1 
ATOM   13931 C CB    . LYS G 3 433 ? 96.600  168.608 223.700 1.00 94.37  ? 403 LYS G CB    1 
ATOM   13932 C CG    . LYS G 3 433 ? 96.879  169.403 224.968 1.00 94.37  ? 403 LYS G CG    1 
ATOM   13933 C CD    . LYS G 3 433 ? 98.379  169.560 225.285 1.00 94.37  ? 403 LYS G CD    1 
ATOM   13934 C CE    . LYS G 3 433 ? 99.299  169.809 224.090 1.00 94.37  ? 403 LYS G CE    1 
ATOM   13935 N NZ    . LYS G 3 433 ? 100.696 170.065 224.550 1.00 94.37  ? 403 LYS G NZ    1 
ATOM   13936 N N     . CYS G 3 434 ? 94.019  169.116 221.813 1.00 99.38  ? 404 CYS G N     1 
ATOM   13937 C CA    . CYS G 3 434 ? 93.048  170.056 221.268 1.00 99.38  ? 404 CYS G CA    1 
ATOM   13938 C C     . CYS G 3 434 ? 91.626  169.570 221.516 1.00 99.38  ? 404 CYS G C     1 
ATOM   13939 O O     . CYS G 3 434 ? 90.720  170.376 221.757 1.00 99.38  ? 404 CYS G O     1 
ATOM   13940 C CB    . CYS G 3 434 ? 93.301  170.250 219.773 1.00 99.38  ? 404 CYS G CB    1 
ATOM   13941 S SG    . CYS G 3 434 ? 92.967  171.899 219.166 1.00 99.38  ? 404 CYS G SG    1 
ATOM   13942 N N     . VAL G 3 435 ? 91.413  168.252 221.454 1.00 102.53 ? 405 VAL G N     1 
ATOM   13943 C CA    . VAL G 3 435 ? 90.122  167.683 221.832 1.00 102.53 ? 405 VAL G CA    1 
ATOM   13944 C C     . VAL G 3 435 ? 89.872  167.918 223.316 1.00 102.53 ? 405 VAL G C     1 
ATOM   13945 O O     . VAL G 3 435 ? 88.729  168.133 223.736 1.00 102.53 ? 405 VAL G O     1 
ATOM   13946 C CB    . VAL G 3 435 ? 90.072  166.181 221.449 1.00 102.53 ? 405 VAL G CB    1 
ATOM   13947 C CG1   . VAL G 3 435 ? 89.133  165.342 222.352 1.00 102.53 ? 405 VAL G CG1   1 
ATOM   13948 C CG2   . VAL G 3 435 ? 89.670  166.026 219.990 1.00 102.53 ? 405 VAL G CG2   1 
ATOM   13949 N N     . ALA G 3 436 ? 90.929  167.873 224.134 1.00 104.88 ? 406 ALA G N     1 
ATOM   13950 C CA    . ALA G 3 436 ? 90.784  168.190 225.552 1.00 104.88 ? 406 ALA G CA    1 
ATOM   13951 C C     . ALA G 3 436 ? 90.390  169.647 225.775 1.00 104.88 ? 406 ALA G C     1 
ATOM   13952 O O     . ALA G 3 436 ? 89.787  169.970 226.805 1.00 104.88 ? 406 ALA G O     1 
ATOM   13953 C CB    . ALA G 3 436 ? 92.086  167.883 226.292 1.00 104.88 ? 406 ALA G CB    1 
ATOM   13954 N N     . SER G 3 437 ? 90.736  170.541 224.841 1.00 104.45 ? 407 SER G N     1 
ATOM   13955 C CA    . SER G 3 437 ? 90.405  171.955 224.999 1.00 104.45 ? 407 SER G CA    1 
ATOM   13956 C C     . SER G 3 437 ? 88.897  172.181 224.990 1.00 104.45 ? 407 SER G C     1 
ATOM   13957 O O     . SER G 3 437 ? 88.383  172.985 225.777 1.00 104.45 ? 407 SER G O     1 
ATOM   13958 C CB    . SER G 3 437 ? 91.072  172.774 223.896 1.00 104.45 ? 407 SER G CB    1 
ATOM   13959 O OG    . SER G 3 437 ? 90.272  172.795 222.728 1.00 104.45 ? 407 SER G OG    1 
ATOM   13960 N N     . PHE G 3 438 ? 88.179  171.491 224.102 1.00 109.02 ? 408 PHE G N     1 
ATOM   13961 C CA    . PHE G 3 438 ? 86.720  171.501 224.034 1.00 109.02 ? 408 PHE G CA    1 
ATOM   13962 C C     . PHE G 3 438 ? 86.172  170.117 224.361 1.00 109.02 ? 408 PHE G C     1 
ATOM   13963 O O     . PHE G 3 438 ? 85.280  169.598 223.686 1.00 109.02 ? 408 PHE G O     1 
ATOM   13964 C CB    . PHE G 3 438 ? 86.222  171.964 222.658 1.00 109.02 ? 408 PHE G CB    1 
ATOM   13965 C CG    . PHE G 3 438 ? 86.494  173.430 222.323 1.00 109.02 ? 408 PHE G CG    1 
ATOM   13966 C CD1   . PHE G 3 438 ? 86.609  174.416 223.300 1.00 109.02 ? 408 PHE G CD1   1 
ATOM   13967 C CD2   . PHE G 3 438 ? 86.577  173.817 220.995 1.00 109.02 ? 408 PHE G CD2   1 
ATOM   13968 C CE1   . PHE G 3 438 ? 86.838  175.736 222.958 1.00 109.02 ? 408 PHE G CE1   1 
ATOM   13969 C CE2   . PHE G 3 438 ? 86.797  175.139 220.650 1.00 109.02 ? 408 PHE G CE2   1 
ATOM   13970 C CZ    . PHE G 3 438 ? 86.931  176.097 221.632 1.00 109.02 ? 408 PHE G CZ    1 
ATOM   13971 N N     . PHE G 3 439 ? 86.714  169.494 225.407 1.00 112.20 ? 409 PHE G N     1 
ATOM   13972 C CA    . PHE G 3 439 ? 86.100  168.281 225.933 1.00 112.20 ? 409 PHE G CA    1 
ATOM   13973 C C     . PHE G 3 439 ? 84.722  168.588 226.503 1.00 112.20 ? 409 PHE G C     1 
ATOM   13974 O O     . PHE G 3 439 ? 83.709  168.070 226.024 1.00 112.20 ? 409 PHE G O     1 
ATOM   13975 C CB    . PHE G 3 439 ? 87.001  167.653 227.001 1.00 112.20 ? 409 PHE G CB    1 
ATOM   13976 C CG    . PHE G 3 439 ? 86.337  166.554 227.787 1.00 112.20 ? 409 PHE G CG    1 
ATOM   13977 C CD1   . PHE G 3 439 ? 85.752  165.474 227.143 1.00 112.20 ? 409 PHE G CD1   1 
ATOM   13978 C CD2   . PHE G 3 439 ? 86.298  166.601 229.170 1.00 112.20 ? 409 PHE G CD2   1 
ATOM   13979 C CE1   . PHE G 3 439 ? 85.139  164.469 227.862 1.00 112.20 ? 409 PHE G CE1   1 
ATOM   13980 C CE2   . PHE G 3 439 ? 85.689  165.595 229.895 1.00 112.20 ? 409 PHE G CE2   1 
ATOM   13981 C CZ    . PHE G 3 439 ? 85.109  164.527 229.240 1.00 112.20 ? 409 PHE G CZ    1 
ATOM   13982 N N     . THR G 3 440 ? 84.663  169.465 227.510 1.00 113.46 ? 410 THR G N     1 
ATOM   13983 C CA    . THR G 3 440 ? 83.407  169.753 228.196 1.00 113.46 ? 410 THR G CA    1 
ATOM   13984 C C     . THR G 3 440 ? 82.369  170.425 227.299 1.00 113.46 ? 410 THR G C     1 
ATOM   13985 O O     . THR G 3 440 ? 81.177  170.378 227.622 1.00 113.46 ? 410 THR G O     1 
ATOM   13986 C CB    . THR G 3 440 ? 83.671  170.641 229.415 1.00 113.46 ? 410 THR G CB    1 
ATOM   13987 O OG1   . THR G 3 440 ? 84.570  171.698 229.056 1.00 113.46 ? 410 THR G OG1   1 
ATOM   13988 C CG2   . THR G 3 440 ? 84.270  169.829 230.556 1.00 113.46 ? 410 THR G CG2   1 
ATOM   13989 N N     . GLU G 3 441 ? 82.785  171.055 226.197 1.00 109.97 ? 411 GLU G N     1 
ATOM   13990 C CA    . GLU G 3 441 ? 81.828  171.750 225.338 1.00 109.97 ? 411 GLU G CA    1 
ATOM   13991 C C     . GLU G 3 441 ? 80.880  170.771 224.651 1.00 109.97 ? 411 GLU G C     1 
ATOM   13992 O O     . GLU G 3 441 ? 79.657  170.949 224.699 1.00 109.97 ? 411 GLU G O     1 
ATOM   13993 C CB    . GLU G 3 441 ? 82.565  172.605 224.302 1.00 109.97 ? 411 GLU G CB    1 
ATOM   13994 C CG    . GLU G 3 441 ? 82.850  174.033 224.761 1.00 109.97 ? 411 GLU G CG    1 
ATOM   13995 C CD    . GLU G 3 441 ? 83.647  174.096 226.051 1.00 109.97 ? 411 GLU G CD    1 
ATOM   13996 O OE1   . GLU G 3 441 ? 84.782  173.576 226.080 1.00 109.97 ? 411 GLU G OE1   1 
ATOM   13997 O OE2   . GLU G 3 441 ? 83.137  174.666 227.038 1.00 109.97 ? 411 GLU G OE2   1 
ATOM   13998 N N     . ASP G 3 442 ? 81.429  169.724 223.990 1.00 110.69 ? 412 ASP G N     1 
ATOM   13999 C CA    . ASP G 3 442 ? 80.627  168.667 223.347 1.00 110.69 ? 412 ASP G CA    1 
ATOM   14000 C C     . ASP G 3 442 ? 81.294  167.332 223.701 1.00 110.69 ? 412 ASP G C     1 
ATOM   14001 O O     . ASP G 3 442 ? 82.041  166.761 222.895 1.00 110.69 ? 412 ASP G O     1 
ATOM   14002 C CB    . ASP G 3 442 ? 80.531  168.889 221.835 1.00 110.69 ? 412 ASP G CB    1 
ATOM   14003 C CG    . ASP G 3 442 ? 79.572  167.922 221.143 1.00 110.69 ? 412 ASP G CG    1 
ATOM   14004 O OD1   . ASP G 3 442 ? 79.057  166.982 221.785 1.00 110.69 ? 412 ASP G OD1   1 
ATOM   14005 O OD2   . ASP G 3 442 ? 79.335  168.108 219.931 1.00 110.69 ? 412 ASP G OD2   1 
ATOM   14006 N N     . MET G 3 443 ? 80.930  166.810 224.880 1.00 112.26 ? 413 MET G N     1 
ATOM   14007 C CA    . MET G 3 443 ? 81.639  165.680 225.480 1.00 112.26 ? 413 MET G CA    1 
ATOM   14008 C C     . MET G 3 443 ? 81.543  164.435 224.612 1.00 112.26 ? 413 MET G C     1 
ATOM   14009 O O     . MET G 3 443 ? 82.558  163.764 224.371 1.00 112.26 ? 413 MET G O     1 
ATOM   14010 C CB    . MET G 3 443 ? 81.068  165.401 226.873 1.00 112.26 ? 413 MET G CB    1 
ATOM   14011 C CG    . MET G 3 443 ? 81.551  166.346 227.972 1.00 112.26 ? 413 MET G CG    1 
ATOM   14012 S SD    . MET G 3 443 ? 81.746  165.529 229.562 1.00 112.26 ? 413 MET G SD    1 
ATOM   14013 C CE    . MET G 3 443 ? 82.371  166.882 230.556 1.00 112.26 ? 413 MET G CE    1 
ATOM   14014 N N     . ASP G 3 444 ? 80.340  164.148 224.101 1.00 110.08 ? 414 ASP G N     1 
ATOM   14015 C CA    . ASP G 3 444 ? 80.128  163.026 223.190 1.00 110.08 ? 414 ASP G CA    1 
ATOM   14016 C C     . ASP G 3 444 ? 81.038  163.130 221.975 1.00 110.08 ? 414 ASP G C     1 
ATOM   14017 O O     . ASP G 3 444 ? 81.726  162.164 221.618 1.00 110.08 ? 414 ASP G O     1 
ATOM   14018 C CB    . ASP G 3 444 ? 78.661  162.982 222.753 1.00 110.08 ? 414 ASP G CB    1 
ATOM   14019 C CG    . ASP G 3 444 ? 78.230  161.609 222.271 1.00 110.08 ? 414 ASP G CG    1 
ATOM   14020 O OD1   . ASP G 3 444 ? 79.076  160.859 221.739 1.00 110.08 ? 414 ASP G OD1   1 
ATOM   14021 O OD2   . ASP G 3 444 ? 77.035  161.279 222.419 1.00 110.08 ? 414 ASP G OD2   1 
ATOM   14022 N N     . LEU G 3 445 ? 81.115  164.330 221.383 1.00 105.81 ? 415 LEU G N     1 
ATOM   14023 C CA    . LEU G 3 445 ? 81.967  164.519 220.216 1.00 105.81 ? 415 LEU G CA    1 
ATOM   14024 C C     . LEU G 3 445 ? 83.423  164.271 220.577 1.00 105.81 ? 415 LEU G C     1 
ATOM   14025 O O     . LEU G 3 445 ? 84.145  163.603 219.823 1.00 105.81 ? 415 LEU G O     1 
ATOM   14026 C CB    . LEU G 3 445 ? 81.766  165.921 219.636 1.00 105.81 ? 415 LEU G CB    1 
ATOM   14027 C CG    . LEU G 3 445 ? 82.606  166.349 218.426 1.00 105.81 ? 415 LEU G CG    1 
ATOM   14028 C CD1   . LEU G 3 445 ? 82.438  165.378 217.266 1.00 105.81 ? 415 LEU G CD1   1 
ATOM   14029 C CD2   . LEU G 3 445 ? 82.226  167.752 217.976 1.00 105.81 ? 415 LEU G CD2   1 
ATOM   14030 N N     . ALA G 3 446 ? 83.826  164.690 221.786 1.00 107.01 ? 416 ALA G N     1 
ATOM   14031 C CA    . ALA G 3 446 ? 85.181  164.413 222.247 1.00 107.01 ? 416 ALA G CA    1 
ATOM   14032 C C     . ALA G 3 446 ? 85.410  162.913 222.362 1.00 107.01 ? 416 ALA G C     1 
ATOM   14033 O O     . ALA G 3 446 ? 86.356  162.380 221.766 1.00 107.01 ? 416 ALA G O     1 
ATOM   14034 C CB    . ALA G 3 446 ? 85.447  165.110 223.581 1.00 107.01 ? 416 ALA G CB    1 
ATOM   14035 N N     . VAL G 3 447 ? 84.480  162.195 223.007 1.00 107.67 ? 417 VAL G N     1 
ATOM   14036 C CA    . VAL G 3 447 ? 84.672  160.752 223.116 1.00 107.67 ? 417 VAL G CA    1 
ATOM   14037 C C     . VAL G 3 447 ? 84.394  160.068 221.791 1.00 107.67 ? 417 VAL G C     1 
ATOM   14038 O O     . VAL G 3 447 ? 84.753  158.895 221.634 1.00 107.67 ? 417 VAL G O     1 
ATOM   14039 C CB    . VAL G 3 447 ? 83.856  160.126 224.277 1.00 107.67 ? 417 VAL G CB    1 
ATOM   14040 C CG1   . VAL G 3 447 ? 82.420  159.775 223.894 1.00 107.67 ? 417 VAL G CG1   1 
ATOM   14041 C CG2   . VAL G 3 447 ? 84.541  158.836 224.765 1.00 107.67 ? 417 VAL G CG2   1 
ATOM   14042 N N     . LYS G 3 448 ? 83.758  160.755 220.832 1.00 103.11 ? 418 LYS G N     1 
ATOM   14043 C CA    . LYS G 3 448 ? 83.748  160.230 219.475 1.00 103.11 ? 418 LYS G CA    1 
ATOM   14044 C C     . LYS G 3 448 ? 85.099  160.462 218.807 1.00 103.11 ? 418 LYS G C     1 
ATOM   14045 O O     . LYS G 3 448 ? 85.677  159.525 218.237 1.00 103.11 ? 418 LYS G O     1 
ATOM   14046 C CB    . LYS G 3 448 ? 82.602  160.859 218.686 1.00 103.11 ? 418 LYS G CB    1 
ATOM   14047 C CG    . LYS G 3 448 ? 82.449  160.320 217.267 1.00 103.11 ? 418 LYS G CG    1 
ATOM   14048 C CD    . LYS G 3 448 ? 81.028  160.503 216.716 1.00 103.11 ? 418 LYS G CD    1 
ATOM   14049 C CE    . LYS G 3 448 ? 80.699  161.944 216.349 1.00 103.11 ? 418 LYS G CE    1 
ATOM   14050 N NZ    . LYS G 3 448 ? 79.240  162.207 216.483 1.00 103.11 ? 418 LYS G NZ    1 
ATOM   14051 N N     . TYR G 3 449 ? 85.652  161.678 218.955 1.00 102.38 ? 419 TYR G N     1 
ATOM   14052 C CA    . TYR G 3 449 ? 86.872  162.060 218.234 1.00 102.38 ? 419 TYR G CA    1 
ATOM   14053 C C     . TYR G 3 449 ? 88.048  161.181 218.631 1.00 102.38 ? 419 TYR G C     1 
ATOM   14054 O O     . TYR G 3 449 ? 88.718  160.598 217.767 1.00 102.38 ? 419 TYR G O     1 
ATOM   14055 C CB    . TYR G 3 449 ? 87.221  163.534 218.483 1.00 102.38 ? 419 TYR G CB    1 
ATOM   14056 C CG    . TYR G 3 449 ? 87.000  164.429 217.286 1.00 102.38 ? 419 TYR G CG    1 
ATOM   14057 C CD1   . TYR G 3 449 ? 87.900  164.438 216.230 1.00 102.38 ? 419 TYR G CD1   1 
ATOM   14058 C CD2   . TYR G 3 449 ? 85.895  165.265 217.210 1.00 102.38 ? 419 TYR G CD2   1 
ATOM   14059 C CE1   . TYR G 3 449 ? 87.702  165.249 215.129 1.00 102.38 ? 419 TYR G CE1   1 
ATOM   14060 C CE2   . TYR G 3 449 ? 85.691  166.084 216.114 1.00 102.38 ? 419 TYR G CE2   1 
ATOM   14061 C CZ    . TYR G 3 449 ? 86.599  166.072 215.077 1.00 102.38 ? 419 TYR G CZ    1 
ATOM   14062 O OH    . TYR G 3 449 ? 86.405  166.883 213.981 1.00 102.38 ? 419 TYR G OH    1 
ATOM   14063 N N     . ILE G 3 450 ? 88.270  161.036 219.942 1.00 100.16 ? 420 ILE G N     1 
ATOM   14064 C CA    . ILE G 3 450 ? 89.316  160.158 220.454 1.00 100.16 ? 420 ILE G CA    1 
ATOM   14065 C C     . ILE G 3 450 ? 89.066  158.728 219.989 1.00 100.16 ? 420 ILE G C     1 
ATOM   14066 O O     . ILE G 3 450 ? 90.000  158.027 219.574 1.00 100.16 ? 420 ILE G O     1 
ATOM   14067 C CB    . ILE G 3 450 ? 89.386  160.277 221.993 1.00 100.16 ? 420 ILE G CB    1 
ATOM   14068 C CG1   . ILE G 3 450 ? 90.181  161.530 222.374 1.00 100.16 ? 420 ILE G CG1   1 
ATOM   14069 C CG2   . ILE G 3 450 ? 90.069  159.054 222.647 1.00 100.16 ? 420 ILE G CG2   1 
ATOM   14070 C CD1   . ILE G 3 450 ? 89.903  162.056 223.780 1.00 100.16 ? 420 ILE G CD1   1 
ATOM   14071 N N     . GLU G 3 451 ? 87.797  158.295 220.000 1.00 100.09 ? 421 GLU G N     1 
ATOM   14072 C CA    . GLU G 3 451 ? 87.474  156.962 219.497 1.00 100.09 ? 421 GLU G CA    1 
ATOM   14073 C C     . GLU G 3 451 ? 87.803  156.868 218.017 1.00 100.09 ? 421 GLU G C     1 
ATOM   14074 O O     . GLU G 3 451 ? 88.391  155.879 217.561 1.00 100.09 ? 421 GLU G O     1 
ATOM   14075 C CB    . GLU G 3 451 ? 85.998  156.633 219.776 1.00 100.09 ? 421 GLU G CB    1 
ATOM   14076 C CG    . GLU G 3 451 ? 85.315  155.547 218.892 1.00 100.09 ? 421 GLU G CG    1 
ATOM   14077 C CD    . GLU G 3 451 ? 84.688  156.062 217.589 1.00 100.09 ? 421 GLU G CD    1 
ATOM   14078 O OE1   . GLU G 3 451 ? 84.270  157.238 217.524 1.00 100.09 ? 421 GLU G OE1   1 
ATOM   14079 O OE2   . GLU G 3 451 ? 84.624  155.277 216.621 1.00 100.09 ? 421 GLU G OE2   1 
ATOM   14080 N N     . ASN G 3 452 ? 87.483  157.919 217.263 1.00 97.29  ? 422 ASN G N     1 
ATOM   14081 C CA    . ASN G 3 452 ? 87.829  157.912 215.852 1.00 97.29  ? 422 ASN G CA    1 
ATOM   14082 C C     . ASN G 3 452 ? 89.339  157.994 215.665 1.00 97.29  ? 422 ASN G C     1 
ATOM   14083 O O     . ASN G 3 452 ? 89.867  157.453 214.685 1.00 97.29  ? 422 ASN G O     1 
ATOM   14084 C CB    . ASN G 3 452 ? 87.102  159.047 215.135 1.00 97.29  ? 422 ASN G CB    1 
ATOM   14085 C CG    . ASN G 3 452 ? 85.742  158.615 214.621 1.00 97.29  ? 422 ASN G CG    1 
ATOM   14086 O OD1   . ASN G 3 452 ? 85.631  157.998 213.562 1.00 97.29  ? 422 ASN G OD1   1 
ATOM   14087 N ND2   . ASN G 3 452 ? 84.702  158.906 215.392 1.00 97.29  ? 422 ASN G ND2   1 
ATOM   14088 N N     . LEU G 3 453 ? 90.059  158.601 216.624 1.00 92.30  ? 423 LEU G N     1 
ATOM   14089 C CA    . LEU G 3 453 ? 91.518  158.568 216.552 1.00 92.30  ? 423 LEU G CA    1 
ATOM   14090 C C     . LEU G 3 453 ? 92.050  157.147 216.695 1.00 92.30  ? 423 LEU G C     1 
ATOM   14091 O O     . LEU G 3 453 ? 93.131  156.840 216.182 1.00 92.30  ? 423 LEU G O     1 
ATOM   14092 C CB    . LEU G 3 453 ? 92.157  159.446 217.629 1.00 92.30  ? 423 LEU G CB    1 
ATOM   14093 C CG    . LEU G 3 453 ? 92.748  160.805 217.252 1.00 92.30  ? 423 LEU G CG    1 
ATOM   14094 C CD1   . LEU G 3 453 ? 91.715  161.702 216.591 1.00 92.30  ? 423 LEU G CD1   1 
ATOM   14095 C CD2   . LEU G 3 453 ? 93.327  161.479 218.489 1.00 92.30  ? 423 LEU G CD2   1 
ATOM   14096 N N     . THR G 3 454 ? 91.318  156.271 217.390 1.00 92.78  ? 424 THR G N     1 
ATOM   14097 C CA    . THR G 3 454 ? 91.723  154.874 217.455 1.00 92.78  ? 424 THR G CA    1 
ATOM   14098 C C     . THR G 3 454 ? 91.608  154.169 216.110 1.00 92.78  ? 424 THR G C     1 
ATOM   14099 O O     . THR G 3 454 ? 92.305  153.170 215.899 1.00 92.78  ? 424 THR G O     1 
ATOM   14100 C CB    . THR G 3 454 ? 90.890  154.138 218.509 1.00 92.78  ? 424 THR G CB    1 
ATOM   14101 O OG1   . THR G 3 454 ? 90.802  154.933 219.698 1.00 92.78  ? 424 THR G OG1   1 
ATOM   14102 C CG2   . THR G 3 454 ? 91.475  152.779 218.841 1.00 92.78  ? 424 THR G CG2   1 
ATOM   14103 N N     . LYS G 3 455 ? 90.772  154.664 215.194 1.00 89.42  ? 425 LYS G N     1 
ATOM   14104 C CA    . LYS G 3 455 ? 90.567  153.995 213.915 1.00 89.42  ? 425 LYS G CA    1 
ATOM   14105 C C     . LYS G 3 455 ? 91.581  154.394 212.846 1.00 89.42  ? 425 LYS G C     1 
ATOM   14106 O O     . LYS G 3 455 ? 91.495  153.884 211.724 1.00 89.42  ? 425 LYS G O     1 
ATOM   14107 C CB    . LYS G 3 455 ? 89.146  154.257 213.403 1.00 89.42  ? 425 LYS G CB    1 
ATOM   14108 C CG    . LYS G 3 455 ? 88.021  154.111 214.445 1.00 89.42  ? 425 LYS G CG    1 
ATOM   14109 C CD    . LYS G 3 455 ? 88.062  152.788 215.219 1.00 89.42  ? 425 LYS G CD    1 
ATOM   14110 C CE    . LYS G 3 455 ? 86.904  152.685 216.199 1.00 89.42  ? 425 LYS G CE    1 
ATOM   14111 N NZ    . LYS G 3 455 ? 85.603  152.506 215.498 1.00 89.42  ? 425 LYS G NZ    1 
ATOM   14112 N N     . VAL G 3 456 ? 92.536  155.270 213.150 1.00 80.85  ? 426 VAL G N     1 
ATOM   14113 C CA    . VAL G 3 456 ? 93.551  155.659 212.173 1.00 80.85  ? 426 VAL G CA    1 
ATOM   14114 C C     . VAL G 3 456 ? 94.510  154.490 211.956 1.00 80.85  ? 426 VAL G C     1 
ATOM   14115 O O     . VAL G 3 456 ? 94.689  153.678 212.875 1.00 80.85  ? 426 VAL G O     1 
ATOM   14116 C CB    . VAL G 3 456 ? 94.315  156.916 212.625 1.00 80.85  ? 426 VAL G CB    1 
ATOM   14117 C CG1   . VAL G 3 456 ? 95.220  156.617 213.832 1.00 80.85  ? 426 VAL G CG1   1 
ATOM   14118 C CG2   . VAL G 3 456 ? 95.133  157.485 211.469 1.00 80.85  ? 426 VAL G CG2   1 
ATOM   14119 N N     . PRO G 3 457 ? 95.147  154.347 210.791 1.00 72.48  ? 427 PRO G N     1 
ATOM   14120 C CA    . PRO G 3 457 ? 96.214  153.350 210.669 1.00 72.48  ? 427 PRO G CA    1 
ATOM   14121 C C     . PRO G 3 457 ? 97.435  153.703 211.506 1.00 72.48  ? 427 PRO G C     1 
ATOM   14122 O O     . PRO G 3 457 ? 97.676  154.860 211.857 1.00 72.48  ? 427 PRO G O     1 
ATOM   14123 C CB    . PRO G 3 457 ? 96.550  153.381 209.177 1.00 72.48  ? 427 PRO G CB    1 
ATOM   14124 C CG    . PRO G 3 457 ? 95.298  153.785 208.536 1.00 72.48  ? 427 PRO G CG    1 
ATOM   14125 C CD    . PRO G 3 457 ? 94.743  154.827 209.454 1.00 72.48  ? 427 PRO G CD    1 
ATOM   14126 N N     . ARG G 3 458 ? 98.222  152.661 211.802 1.00 65.59  ? 428 ARG G N     1 
ATOM   14127 C CA    . ARG G 3 458 ? 99.484  152.756 212.555 1.00 65.59  ? 428 ARG G CA    1 
ATOM   14128 C C     . ARG G 3 458 ? 99.277  153.434 213.917 1.00 65.59  ? 428 ARG G C     1 
ATOM   14129 O O     . ARG G 3 458 ? 100.141 154.144 214.437 1.00 65.59  ? 428 ARG G O     1 
ATOM   14130 C CB    . ARG G 3 458 ? 100.581 153.441 211.703 1.00 65.59  ? 428 ARG G CB    1 
ATOM   14131 C CG    . ARG G 3 458 ? 101.467 152.432 210.953 1.00 65.59  ? 428 ARG G CG    1 
ATOM   14132 C CD    . ARG G 3 458 ? 102.747 153.011 210.349 1.00 65.59  ? 428 ARG G CD    1 
ATOM   14133 N NE    . ARG G 3 458 ? 102.541 153.700 209.078 1.00 65.59  ? 428 ARG G NE    1 
ATOM   14134 C CZ    . ARG G 3 458 ? 102.785 153.196 207.871 1.00 65.59  ? 428 ARG G CZ    1 
ATOM   14135 N NH1   . ARG G 3 458 ? 102.946 151.895 207.670 1.00 65.59  ? 428 ARG G NH1   1 
ATOM   14136 N NH2   . ARG G 3 458 ? 102.832 154.015 206.825 1.00 65.59  ? 428 ARG G NH2   1 
ATOM   14137 N N     . PHE G 3 459 ? 98.124  153.175 214.534 1.00 80.90  ? 429 PHE G N     1 
ATOM   14138 C CA    . PHE G 3 459 ? 97.828  153.770 215.832 1.00 80.90  ? 429 PHE G CA    1 
ATOM   14139 C C     . PHE G 3 459 ? 98.675  153.150 216.937 1.00 80.90  ? 429 PHE G C     1 
ATOM   14140 O O     . PHE G 3 459 ? 99.126  153.856 217.848 1.00 80.90  ? 429 PHE G O     1 
ATOM   14141 C CB    . PHE G 3 459 ? 96.342  153.598 216.148 1.00 80.90  ? 429 PHE G CB    1 
ATOM   14142 C CG    . PHE G 3 459 ? 95.929  154.125 217.498 1.00 80.90  ? 429 PHE G CG    1 
ATOM   14143 C CD1   . PHE G 3 459 ? 96.344  155.368 217.949 1.00 80.90  ? 429 PHE G CD1   1 
ATOM   14144 C CD2   . PHE G 3 459 ? 95.141  153.350 218.330 1.00 80.90  ? 429 PHE G CD2   1 
ATOM   14145 C CE1   . PHE G 3 459 ? 95.958  155.833 219.185 1.00 80.90  ? 429 PHE G CE1   1 
ATOM   14146 C CE2   . PHE G 3 459 ? 94.758  153.810 219.571 1.00 80.90  ? 429 PHE G CE2   1 
ATOM   14147 C CZ    . PHE G 3 459 ? 95.171  155.049 220.000 1.00 80.90  ? 429 PHE G CZ    1 
ATOM   14148 N N     . ASN G 3 460 ? 98.885  151.830 216.876 1.00 75.04  ? 430 ASN G N     1 
ATOM   14149 C CA    . ASN G 3 460 ? 99.515  151.104 217.980 1.00 75.04  ? 430 ASN G CA    1 
ATOM   14150 C C     . ASN G 3 460 ? 100.971 151.542 218.103 1.00 75.04  ? 430 ASN G C     1 
ATOM   14151 O O     . ASN G 3 460 ? 101.443 151.869 219.200 1.00 75.04  ? 430 ASN G O     1 
ATOM   14152 C CB    . ASN G 3 460 ? 99.341  149.582 217.720 1.00 75.04  ? 430 ASN G CB    1 
ATOM   14153 C CG    . ASN G 3 460 ? 100.356 148.628 218.448 1.00 75.04  ? 430 ASN G CG    1 
ATOM   14154 O OD1   . ASN G 3 460 ? 101.117 148.966 219.361 1.00 75.04  ? 430 ASN G OD1   1 
ATOM   14155 N ND2   . ASN G 3 460 ? 100.346 147.385 217.981 1.00 75.04  ? 430 ASN G ND2   1 
ATOM   14156 N N     . MET G 3 461 ? 101.700 151.554 216.985 1.00 69.42  ? 431 MET G N     1 
ATOM   14157 C CA    . MET G 3 461 ? 103.068 152.055 217.012 1.00 69.42  ? 431 MET G CA    1 
ATOM   14158 C C     . MET G 3 461 ? 103.108 153.534 217.369 1.00 69.42  ? 431 MET G C     1 
ATOM   14159 O O     . MET G 3 461 ? 104.074 153.990 217.988 1.00 69.42  ? 431 MET G O     1 
ATOM   14160 C CB    . MET G 3 461 ? 103.758 151.800 215.666 1.00 69.42  ? 431 MET G CB    1 
ATOM   14161 C CG    . MET G 3 461 ? 103.157 152.511 214.447 1.00 69.42  ? 431 MET G CG    1 
ATOM   14162 S SD    . MET G 3 461 ? 103.848 154.150 214.128 1.00 69.42  ? 431 MET G SD    1 
ATOM   14163 C CE    . MET G 3 461 ? 105.389 153.715 213.328 1.00 69.42  ? 431 MET G CE    1 
ATOM   14164 N N     . LEU G 3 462 ? 102.070 154.291 216.996 1.00 75.70  ? 432 LEU G N     1 
ATOM   14165 C CA    . LEU G 3 462 ? 102.028 155.717 217.313 1.00 75.70  ? 432 LEU G CA    1 
ATOM   14166 C C     . LEU G 3 462 ? 101.990 155.945 218.820 1.00 75.70  ? 432 LEU G C     1 
ATOM   14167 O O     . LEU G 3 462 ? 102.761 156.752 219.353 1.00 75.70  ? 432 LEU G O     1 
ATOM   14168 C CB    . LEU G 3 462 ? 100.816 156.382 216.650 1.00 75.70  ? 432 LEU G CB    1 
ATOM   14169 C CG    . LEU G 3 462 ? 101.074 157.197 215.381 1.00 75.70  ? 432 LEU G CG    1 
ATOM   14170 C CD1   . LEU G 3 462 ? 99.755  157.468 214.683 1.00 75.70  ? 432 LEU G CD1   1 
ATOM   14171 C CD2   . LEU G 3 462 ? 101.781 158.508 215.679 1.00 75.70  ? 432 LEU G CD2   1 
ATOM   14172 N N     . VAL G 3 463 ? 101.096 155.244 219.527 1.00 82.58  ? 433 VAL G N     1 
ATOM   14173 C CA    . VAL G 3 463 ? 101.066 155.395 220.983 1.00 82.58  ? 433 VAL G CA    1 
ATOM   14174 C C     . VAL G 3 463 ? 102.316 154.785 221.605 1.00 82.58  ? 433 VAL G C     1 
ATOM   14175 O O     . VAL G 3 463 ? 102.790 155.256 222.645 1.00 82.58  ? 433 VAL G O     1 
ATOM   14176 C CB    . VAL G 3 463 ? 99.783  154.806 221.613 1.00 82.58  ? 433 VAL G CB    1 
ATOM   14177 C CG1   . VAL G 3 463 ? 98.600  155.706 221.307 1.00 82.58  ? 433 VAL G CG1   1 
ATOM   14178 C CG2   . VAL G 3 463 ? 99.512  153.349 221.204 1.00 82.58  ? 433 VAL G CG2   1 
ATOM   14179 N N     . MET G 3 464 ? 102.874 153.738 220.989 1.00 75.12  ? 434 MET G N     1 
ATOM   14180 C CA    . MET G 3 464 ? 104.166 153.227 221.437 1.00 75.12  ? 434 MET G CA    1 
ATOM   14181 C C     . MET G 3 464 ? 105.304 154.218 221.206 1.00 75.12  ? 434 MET G C     1 
ATOM   14182 O O     . MET G 3 464 ? 106.329 154.128 221.890 1.00 75.12  ? 434 MET G O     1 
ATOM   14183 C CB    . MET G 3 464 ? 104.493 151.908 220.726 1.00 75.12  ? 434 MET G CB    1 
ATOM   14184 C CG    . MET G 3 464 ? 105.340 150.900 221.526 1.00 75.12  ? 434 MET G CG    1 
ATOM   14185 S SD    . MET G 3 464 ? 104.769 150.364 223.159 1.00 75.12  ? 434 MET G SD    1 
ATOM   14186 C CE    . MET G 3 464 ? 102.999 150.250 222.924 1.00 75.12  ? 434 MET G CE    1 
ATOM   14187 N N     . CYS G 3 465 ? 105.153 155.157 220.271 1.00 73.42  ? 435 CYS G N     1 
ATOM   14188 C CA    . CYS G 3 465 ? 106.208 156.109 219.942 1.00 73.42  ? 435 CYS G CA    1 
ATOM   14189 C C     . CYS G 3 465 ? 106.254 157.315 220.879 1.00 73.42  ? 435 CYS G C     1 
ATOM   14190 O O     . CYS G 3 465 ? 107.128 158.170 220.706 1.00 73.42  ? 435 CYS G O     1 
ATOM   14191 C CB    . CYS G 3 465 ? 106.029 156.587 218.497 1.00 73.42  ? 435 CYS G CB    1 
ATOM   14192 S SG    . CYS G 3 465 ? 107.507 157.240 217.721 1.00 73.42  ? 435 CYS G SG    1 
ATOM   14193 N N     . LEU G 3 466 ? 105.355 157.412 221.857 1.00 82.09  ? 436 LEU G N     1 
ATOM   14194 C CA    . LEU G 3 466 ? 105.310 158.585 222.719 1.00 82.09  ? 436 LEU G CA    1 
ATOM   14195 C C     . LEU G 3 466 ? 106.526 158.638 223.636 1.00 82.09  ? 436 LEU G C     1 
ATOM   14196 O O     . LEU G 3 466 ? 106.959 157.619 224.182 1.00 82.09  ? 436 LEU G O     1 
ATOM   14197 C CB    . LEU G 3 466 ? 104.034 158.572 223.561 1.00 82.09  ? 436 LEU G CB    1 
ATOM   14198 C CG    . LEU G 3 466 ? 102.707 158.666 222.804 1.00 82.09  ? 436 LEU G CG    1 
ATOM   14199 C CD1   . LEU G 3 466 ? 101.560 158.200 223.686 1.00 82.09  ? 436 LEU G CD1   1 
ATOM   14200 C CD2   . LEU G 3 466 ? 102.464 160.079 222.313 1.00 82.09  ? 436 LEU G CD2   1 
ATOM   14201 N N     . THR G 3 467 ? 107.072 159.841 223.806 1.00 80.35  ? 437 THR G N     1 
ATOM   14202 C CA    . THR G 3 467 ? 108.135 160.076 224.770 1.00 80.35  ? 437 THR G CA    1 
ATOM   14203 C C     . THR G 3 467 ? 107.544 160.220 226.172 1.00 80.35  ? 437 THR G C     1 
ATOM   14204 O O     . THR G 3 467 ? 106.334 160.378 226.352 1.00 80.35  ? 437 THR G O     1 
ATOM   14205 C CB    . THR G 3 467 ? 108.938 161.319 224.390 1.00 80.35  ? 437 THR G CB    1 
ATOM   14206 O OG1   . THR G 3 467 ? 108.064 162.303 223.826 1.00 80.35  ? 437 THR G OG1   1 
ATOM   14207 C CG2   . THR G 3 467 ? 110.021 160.969 223.379 1.00 80.35  ? 437 THR G CG2   1 
ATOM   14208 N N     . SER G 3 468 ? 108.424 160.158 227.176 1.00 88.87  ? 438 SER G N     1 
ATOM   14209 C CA    . SER G 3 468 ? 107.974 160.131 228.566 1.00 88.87  ? 438 SER G CA    1 
ATOM   14210 C C     . SER G 3 468 ? 107.291 161.432 228.974 1.00 88.87  ? 438 SER G C     1 
ATOM   14211 O O     . SER G 3 468 ? 106.382 161.411 229.812 1.00 88.87  ? 438 SER G O     1 
ATOM   14212 C CB    . SER G 3 468 ? 109.159 159.843 229.488 1.00 88.87  ? 438 SER G CB    1 
ATOM   14213 O OG    . SER G 3 468 ? 108.725 159.586 230.812 1.00 88.87  ? 438 SER G OG    1 
ATOM   14214 N N     . THR G 3 469 ? 107.711 162.563 228.401 1.00 89.08  ? 439 THR G N     1 
ATOM   14215 C CA    . THR G 3 469 ? 107.081 163.842 228.718 1.00 89.08  ? 439 THR G CA    1 
ATOM   14216 C C     . THR G 3 469 ? 105.625 163.861 228.268 1.00 89.08  ? 439 THR G C     1 
ATOM   14217 O O     . THR G 3 469 ? 104.725 164.243 229.032 1.00 89.08  ? 439 THR G O     1 
ATOM   14218 C CB    . THR G 3 469 ? 107.862 164.978 228.053 1.00 89.08  ? 439 THR G CB    1 
ATOM   14219 O OG1   . THR G 3 469 ? 109.258 164.833 228.338 1.00 89.08  ? 439 THR G OG1   1 
ATOM   14220 C CG2   . THR G 3 469 ? 107.384 166.338 228.547 1.00 89.08  ? 439 THR G CG2   1 
ATOM   14221 N N     . GLU G 3 470 ? 105.377 163.446 227.024 1.00 89.17  ? 440 GLU G N     1 
ATOM   14222 C CA    . GLU G 3 470 ? 104.010 163.388 226.523 1.00 89.17  ? 440 GLU G CA    1 
ATOM   14223 C C     . GLU G 3 470 ? 103.190 162.355 227.283 1.00 89.17  ? 440 GLU G C     1 
ATOM   14224 O O     . GLU G 3 470 ? 102.004 162.576 227.537 1.00 89.17  ? 440 GLU G O     1 
ATOM   14225 C CB    . GLU G 3 470 ? 104.007 163.082 225.024 1.00 89.17  ? 440 GLU G CB    1 
ATOM   14226 C CG    . GLU G 3 470 ? 104.589 164.191 224.151 1.00 89.17  ? 440 GLU G CG    1 
ATOM   14227 C CD    . GLU G 3 470 ? 104.635 163.823 222.684 1.00 89.17  ? 440 GLU G CD    1 
ATOM   14228 O OE1   . GLU G 3 470 ? 104.395 162.644 222.355 1.00 89.17  ? 440 GLU G OE1   1 
ATOM   14229 O OE2   . GLU G 3 470 ? 104.923 164.714 221.858 1.00 89.17  ? 440 GLU G OE2   1 
ATOM   14230 N N     . LYS G 3 471 ? 103.805 161.230 227.664 1.00 91.05  ? 441 LYS G N     1 
ATOM   14231 C CA    . LYS G 3 471 ? 103.097 160.221 228.450 1.00 91.05  ? 441 LYS G CA    1 
ATOM   14232 C C     . LYS G 3 471 ? 102.652 160.783 229.796 1.00 91.05  ? 441 LYS G C     1 
ATOM   14233 O O     . LYS G 3 471 ? 101.491 160.621 230.202 1.00 91.05  ? 441 LYS G O     1 
ATOM   14234 C CB    . LYS G 3 471 ? 103.994 159.002 228.660 1.00 91.05  ? 441 LYS G CB    1 
ATOM   14235 C CG    . LYS G 3 471 ? 104.141 158.107 227.445 1.00 91.05  ? 441 LYS G CG    1 
ATOM   14236 C CD    . LYS G 3 471 ? 105.123 156.977 227.714 1.00 91.05  ? 441 LYS G CD    1 
ATOM   14237 C CE    . LYS G 3 471 ? 105.094 155.942 226.604 1.00 91.05  ? 441 LYS G CE    1 
ATOM   14238 N NZ    . LYS G 3 471 ? 103.941 155.012 226.751 1.00 91.05  ? 441 LYS G NZ    1 
ATOM   14239 N N     . ASN G 3 472 ? 103.561 161.475 230.490 1.00 94.78  ? 442 ASN G N     1 
ATOM   14240 C CA    . ASN G 3 472 ? 103.227 162.056 231.785 1.00 94.78  ? 442 ASN G CA    1 
ATOM   14241 C C     . ASN G 3 472 ? 102.148 163.122 231.654 1.00 94.78  ? 442 ASN G C     1 
ATOM   14242 O O     . ASN G 3 472 ? 101.220 163.175 232.471 1.00 94.78  ? 442 ASN G O     1 
ATOM   14243 C CB    . ASN G 3 472 ? 104.479 162.645 232.439 1.00 94.78  ? 442 ASN G CB    1 
ATOM   14244 C CG    . ASN G 3 472 ? 105.542 161.598 232.723 1.00 94.78  ? 442 ASN G CG    1 
ATOM   14245 O OD1   . ASN G 3 472 ? 105.261 160.399 232.733 1.00 94.78  ? 442 ASN G OD1   1 
ATOM   14246 N ND2   . ASN G 3 472 ? 106.769 162.049 232.961 1.00 94.78  ? 442 ASN G ND2   1 
ATOM   14247 N N     . GLU G 3 473 ? 102.231 163.967 230.618 1.00 98.89  ? 443 GLU G N     1 
ATOM   14248 C CA    . GLU G 3 473 ? 101.260 165.053 230.529 1.00 98.89  ? 443 GLU G CA    1 
ATOM   14249 C C     . GLU G 3 473 ? 99.907  164.504 230.075 1.00 98.89  ? 443 GLU G C     1 
ATOM   14250 O O     . GLU G 3 473 ? 98.868  165.062 230.437 1.00 98.89  ? 443 GLU G O     1 
ATOM   14251 C CB    . GLU G 3 473 ? 101.824 166.181 229.634 1.00 98.89  ? 443 GLU G CB    1 
ATOM   14252 C CG    . GLU G 3 473 ? 100.896 167.329 229.058 1.00 98.89  ? 443 GLU G CG    1 
ATOM   14253 C CD    . GLU G 3 473 ? 99.803  166.974 228.062 1.00 98.89  ? 443 GLU G CD    1 
ATOM   14254 O OE1   . GLU G 3 473 ? 98.861  167.776 227.926 1.00 98.89  ? 443 GLU G OE1   1 
ATOM   14255 O OE2   . GLU G 3 473 ? 99.904  165.921 227.410 1.00 98.89  ? 443 GLU G OE2   1 
ATOM   14256 N N     . LEU G 3 474 ? 99.889  163.425 229.278 1.00 97.88  ? 444 LEU G N     1 
ATOM   14257 C CA    . LEU G 3 474 ? 98.622  162.761 228.966 1.00 97.88  ? 444 LEU G CA    1 
ATOM   14258 C C     . LEU G 3 474 ? 97.994  162.159 230.213 1.00 97.88  ? 444 LEU G C     1 
ATOM   14259 O O     . LEU G 3 474 ? 96.771  162.200 230.372 1.00 97.88  ? 444 LEU G O     1 
ATOM   14260 C CB    . LEU G 3 474 ? 98.809  161.671 227.901 1.00 97.88  ? 444 LEU G CB    1 
ATOM   14261 C CG    . LEU G 3 474 ? 98.593  161.988 226.409 1.00 97.88  ? 444 LEU G CG    1 
ATOM   14262 C CD1   . LEU G 3 474 ? 97.137  162.410 226.133 1.00 97.88  ? 444 LEU G CD1   1 
ATOM   14263 C CD2   . LEU G 3 474 ? 99.558  163.020 225.855 1.00 97.88  ? 444 LEU G CD2   1 
ATOM   14264 N N     . LEU G 3 475 ? 98.809  161.583 231.101 1.00 104.58 ? 445 LEU G N     1 
ATOM   14265 C CA    . LEU G 3 475 ? 98.276  161.112 232.381 1.00 104.58 ? 445 LEU G CA    1 
ATOM   14266 C C     . LEU G 3 475 ? 97.706  162.272 233.196 1.00 104.58 ? 445 LEU G C     1 
ATOM   14267 O O     . LEU G 3 475 ? 96.647  162.143 233.835 1.00 104.58 ? 445 LEU G O     1 
ATOM   14268 C CB    . LEU G 3 475 ? 99.368  160.389 233.175 1.00 104.58 ? 445 LEU G CB    1 
ATOM   14269 C CG    . LEU G 3 475 ? 99.485  158.866 233.035 1.00 104.58 ? 445 LEU G CG    1 
ATOM   14270 C CD1   . LEU G 3 475 ? 98.495  158.189 233.965 1.00 104.58 ? 445 LEU G CD1   1 
ATOM   14271 C CD2   . LEU G 3 475 ? 99.290  158.381 231.598 1.00 104.58 ? 445 LEU G CD2   1 
ATOM   14272 N N     . LYS G 3 476 ? 98.399  163.415 233.178 1.00 103.46 ? 446 LYS G N     1 
ATOM   14273 C CA    . LYS G 3 476 ? 97.901  164.595 233.880 1.00 103.46 ? 446 LYS G CA    1 
ATOM   14274 C C     . LYS G 3 476 ? 96.573  165.065 233.293 1.00 103.46 ? 446 LYS G C     1 
ATOM   14275 O O     . LYS G 3 476 ? 95.639  165.381 234.036 1.00 103.46 ? 446 LYS G O     1 
ATOM   14276 C CB    . LYS G 3 476 ? 98.937  165.719 233.839 1.00 103.46 ? 446 LYS G CB    1 
ATOM   14277 C CG    . LYS G 3 476 ? 100.124 165.487 234.776 1.00 103.46 ? 446 LYS G CG    1 
ATOM   14278 C CD    . LYS G 3 476 ? 100.992 166.734 234.953 1.00 103.46 ? 446 LYS G CD    1 
ATOM   14279 C CE    . LYS G 3 476 ? 100.350 167.755 235.893 1.00 103.46 ? 446 LYS G CE    1 
ATOM   14280 N NZ    . LYS G 3 476 ? 101.303 168.826 236.301 1.00 103.46 ? 446 LYS G NZ    1 
ATOM   14281 N N     . ILE G 3 477 ? 96.466  165.085 231.962 1.00 105.30 ? 447 ILE G N     1 
ATOM   14282 C CA    . ILE G 3 477 ? 95.226  165.491 231.300 1.00 105.30 ? 447 ILE G CA    1 
ATOM   14283 C C     . ILE G 3 477 ? 94.114  164.492 231.604 1.00 105.30 ? 447 ILE G C     1 
ATOM   14284 O O     . ILE G 3 477 ? 92.939  164.873 231.688 1.00 105.30 ? 447 ILE G O     1 
ATOM   14285 C CB    . ILE G 3 477 ? 95.467  165.659 229.778 1.00 105.30 ? 447 ILE G CB    1 
ATOM   14286 C CG1   . ILE G 3 477 ? 95.998  167.070 229.478 1.00 105.30 ? 447 ILE G CG1   1 
ATOM   14287 C CG2   . ILE G 3 477 ? 94.203  165.371 228.909 1.00 105.30 ? 447 ILE G CG2   1 
ATOM   14288 C CD1   . ILE G 3 477 ? 94.941  168.164 229.397 1.00 105.30 ? 447 ILE G CD1   1 
ATOM   14289 N N     . TRP G 3 478 ? 94.453  163.205 231.724 1.00 108.81 ? 448 TRP G N     1 
ATOM   14290 C CA    . TRP G 3 478 ? 93.463  162.196 232.088 1.00 108.81 ? 448 TRP G CA    1 
ATOM   14291 C C     . TRP G 3 478 ? 92.871  162.487 233.459 1.00 108.81 ? 448 TRP G C     1 
ATOM   14292 O O     . TRP G 3 478 ? 91.645  162.524 233.622 1.00 108.81 ? 448 TRP G O     1 
ATOM   14293 C CB    . TRP G 3 478 ? 94.107  160.805 232.073 1.00 108.81 ? 448 TRP G CB    1 
ATOM   14294 C CG    . TRP G 3 478 ? 93.177  159.644 232.372 1.00 108.81 ? 448 TRP G CG    1 
ATOM   14295 C CD1   . TRP G 3 478 ? 91.817  159.599 232.210 1.00 108.81 ? 448 TRP G CD1   1 
ATOM   14296 C CD2   . TRP G 3 478 ? 93.555  158.365 232.899 1.00 108.81 ? 448 TRP G CD2   1 
ATOM   14297 N NE1   . TRP G 3 478 ? 91.334  158.374 232.597 1.00 108.81 ? 448 TRP G NE1   1 
ATOM   14298 C CE2   . TRP G 3 478 ? 92.380  157.598 233.023 1.00 108.81 ? 448 TRP G CE2   1 
ATOM   14299 C CE3   . TRP G 3 478 ? 94.775  157.793 233.272 1.00 108.81 ? 448 TRP G CE3   1 
ATOM   14300 C CZ2   . TRP G 3 478 ? 92.389  156.291 233.506 1.00 108.81 ? 448 TRP G CZ2   1 
ATOM   14301 C CZ3   . TRP G 3 478 ? 94.783  156.495 233.751 1.00 108.81 ? 448 TRP G CZ3   1 
ATOM   14302 C CH2   . TRP G 3 478 ? 93.597  155.759 233.863 1.00 108.81 ? 448 TRP G CH2   1 
ATOM   14303 N N     . GLU G 3 479 ? 93.728  162.695 234.463 1.00 109.11 ? 449 GLU G N     1 
ATOM   14304 C CA    . GLU G 3 479 ? 93.189  162.952 235.801 1.00 109.11 ? 449 GLU G CA    1 
ATOM   14305 C C     . GLU G 3 479 ? 92.499  164.313 235.884 1.00 109.11 ? 449 GLU G C     1 
ATOM   14306 O O     . GLU G 3 479 ? 91.560  164.472 236.672 1.00 109.11 ? 449 GLU G O     1 
ATOM   14307 C CB    . GLU G 3 479 ? 94.270  162.826 236.890 1.00 109.11 ? 449 GLU G CB    1 
ATOM   14308 C CG    . GLU G 3 479 ? 95.572  163.627 236.740 1.00 109.11 ? 449 GLU G CG    1 
ATOM   14309 C CD    . GLU G 3 479 ? 95.454  165.109 237.080 1.00 109.11 ? 449 GLU G CD    1 
ATOM   14310 O OE1   . GLU G 3 479 ? 94.511  165.500 237.800 1.00 109.11 ? 449 GLU G OE1   1 
ATOM   14311 O OE2   . GLU G 3 479 ? 96.322  165.886 236.633 1.00 109.11 ? 449 GLU G OE2   1 
ATOM   14312 N N     . ASP G 3 480 ? 92.928  165.293 235.077 1.00 109.81 ? 450 ASP G N     1 
ATOM   14313 C CA    . ASP G 3 480 ? 92.349  166.636 235.143 1.00 109.81 ? 450 ASP G CA    1 
ATOM   14314 C C     . ASP G 3 480 ? 91.045  166.720 234.357 1.00 109.81 ? 450 ASP G C     1 
ATOM   14315 O O     . ASP G 3 480 ? 89.985  167.002 234.924 1.00 109.81 ? 450 ASP G O     1 
ATOM   14316 C CB    . ASP G 3 480 ? 93.337  167.686 234.593 1.00 109.81 ? 450 ASP G CB    1 
ATOM   14317 C CG    . ASP G 3 480 ? 94.038  168.528 235.680 1.00 109.81 ? 450 ASP G CG    1 
ATOM   14318 O OD1   . ASP G 3 480 ? 93.674  168.518 236.876 1.00 109.81 ? 450 ASP G OD1   1 
ATOM   14319 O OD2   . ASP G 3 480 ? 95.000  169.231 235.306 1.00 109.81 ? 450 ASP G OD2   1 
ATOM   14320 N N     . VAL G 3 481 ? 91.107  166.466 233.049 1.00 110.02 ? 451 VAL G N     1 
ATOM   14321 C CA    . VAL G 3 481 ? 90.039  166.840 232.125 1.00 110.02 ? 451 VAL G CA    1 
ATOM   14322 C C     . VAL G 3 481 ? 89.128  165.649 231.860 1.00 110.02 ? 451 VAL G C     1 
ATOM   14323 O O     . VAL G 3 481 ? 87.926  165.695 232.146 1.00 110.02 ? 451 VAL G O     1 
ATOM   14324 C CB    . VAL G 3 481 ? 90.628  167.388 230.808 1.00 110.02 ? 451 VAL G CB    1 
ATOM   14325 C CG1   . VAL G 3 481 ? 89.534  167.587 229.750 1.00 110.02 ? 451 VAL G CG1   1 
ATOM   14326 C CG2   . VAL G 3 481 ? 91.381  168.698 231.056 1.00 110.02 ? 451 VAL G CG2   1 
ATOM   14327 N N     . PHE G 3 482 ? 89.691  164.577 231.308 1.00 108.00 ? 452 PHE G N     1 
ATOM   14328 C CA    . PHE G 3 482 ? 88.894  163.463 230.811 1.00 108.00 ? 452 PHE G CA    1 
ATOM   14329 C C     . PHE G 3 482 ? 88.361  162.546 231.909 1.00 108.00 ? 452 PHE G C     1 
ATOM   14330 O O     . PHE G 3 482 ? 87.583  161.641 231.591 1.00 108.00 ? 452 PHE G O     1 
ATOM   14331 C CB    . PHE G 3 482 ? 89.729  162.630 229.827 1.00 108.00 ? 452 PHE G CB    1 
ATOM   14332 C CG    . PHE G 3 482 ? 90.097  163.346 228.536 1.00 108.00 ? 452 PHE G CG    1 
ATOM   14333 C CD1   . PHE G 3 482 ? 89.151  164.021 227.773 1.00 108.00 ? 452 PHE G CD1   1 
ATOM   14334 C CD2   . PHE G 3 482 ? 91.410  163.333 228.090 1.00 108.00 ? 452 PHE G CD2   1 
ATOM   14335 C CE1   . PHE G 3 482 ? 89.510  164.661 226.602 1.00 108.00 ? 452 PHE G CE1   1 
ATOM   14336 C CE2   . PHE G 3 482 ? 91.770  163.970 226.920 1.00 108.00 ? 452 PHE G CE2   1 
ATOM   14337 C CZ    . PHE G 3 482 ? 90.819  164.634 226.176 1.00 108.00 ? 452 PHE G CZ    1 
ATOM   14338 N N     . CYS G 3 483 ? 88.758  162.733 233.170 1.00 112.14 ? 453 CYS G N     1 
ATOM   14339 C CA    . CYS G 3 483 ? 88.248  161.956 234.298 1.00 112.14 ? 453 CYS G CA    1 
ATOM   14340 C C     . CYS G 3 483 ? 87.894  162.871 235.461 1.00 112.14 ? 453 CYS G C     1 
ATOM   14341 O O     . CYS G 3 483 ? 88.170  162.565 236.626 1.00 112.14 ? 453 CYS G O     1 
ATOM   14342 C CB    . CYS G 3 483 ? 89.258  160.894 234.728 1.00 112.14 ? 453 CYS G CB    1 
ATOM   14343 S SG    . CYS G 3 483 ? 88.558  159.573 235.748 1.00 112.14 ? 453 CYS G SG    1 
ATOM   14344 N N     . ASN G 3 484 ? 87.270  164.008 235.155 1.00 112.46 ? 454 ASN G N     1 
ATOM   14345 C CA    . ASN G 3 484 ? 86.778  164.916 236.188 1.00 112.46 ? 454 ASN G CA    1 
ATOM   14346 C C     . ASN G 3 484 ? 85.421  164.425 236.694 1.00 112.46 ? 454 ASN G C     1 
ATOM   14347 O O     . ASN G 3 484 ? 84.814  163.506 236.140 1.00 112.46 ? 454 ASN G O     1 
ATOM   14348 C CB    . ASN G 3 484 ? 86.662  166.373 235.691 1.00 112.46 ? 454 ASN G CB    1 
ATOM   14349 C CG    . ASN G 3 484 ? 85.956  166.514 234.343 1.00 112.46 ? 454 ASN G CG    1 
ATOM   14350 O OD1   . ASN G 3 484 ? 84.889  165.941 234.124 1.00 112.46 ? 454 ASN G OD1   1 
ATOM   14351 N ND2   . ASN G 3 484 ? 86.556  167.279 233.436 1.00 112.46 ? 454 ASN G ND2   1 
ATOM   14352 N N     . LYS G 3 485 ? 84.949  165.046 237.774 1.00 111.63 ? 455 LYS G N     1 
ATOM   14353 C CA    . LYS G 3 485 ? 83.640  164.717 238.322 1.00 111.63 ? 455 LYS G CA    1 
ATOM   14354 C C     . LYS G 3 485 ? 82.489  165.274 237.490 1.00 111.63 ? 455 LYS G C     1 
ATOM   14355 O O     . LYS G 3 485 ? 81.353  164.816 237.652 1.00 111.63 ? 455 LYS G O     1 
ATOM   14356 C CB    . LYS G 3 485 ? 83.519  165.241 239.758 1.00 111.63 ? 455 LYS G CB    1 
ATOM   14357 C CG    . LYS G 3 485 ? 84.669  164.870 240.706 1.00 111.63 ? 455 LYS G CG    1 
ATOM   14358 C CD    . LYS G 3 485 ? 84.816  163.363 240.900 1.00 111.63 ? 455 LYS G CD    1 
ATOM   14359 C CE    . LYS G 3 485 ? 85.974  163.023 241.830 1.00 111.63 ? 455 LYS G CE    1 
ATOM   14360 N NZ    . LYS G 3 485 ? 85.808  163.582 243.201 1.00 111.63 ? 455 LYS G NZ    1 
ATOM   14361 N N     . ALA G 3 486 ? 82.748  166.249 236.611 1.00 111.91 ? 456 ALA G N     1 
ATOM   14362 C CA    . ALA G 3 486 ? 81.666  166.881 235.863 1.00 111.91 ? 456 ALA G CA    1 
ATOM   14363 C C     . ALA G 3 486 ? 81.052  165.928 234.843 1.00 111.91 ? 456 ALA G C     1 
ATOM   14364 O O     . ALA G 3 486 ? 79.832  165.928 234.644 1.00 111.91 ? 456 ALA G O     1 
ATOM   14365 C CB    . ALA G 3 486 ? 82.182  168.141 235.169 1.00 111.91 ? 456 ALA G CB    1 
ATOM   14366 N N     . THR G 3 487 ? 81.877  165.119 234.182 1.00 114.51 ? 457 THR G N     1 
ATOM   14367 C CA    . THR G 3 487 ? 81.384  164.275 233.105 1.00 114.51 ? 457 THR G CA    1 
ATOM   14368 C C     . THR G 3 487 ? 80.507  163.152 233.672 1.00 114.51 ? 457 THR G C     1 
ATOM   14369 O O     . THR G 3 487 ? 80.728  162.706 234.802 1.00 114.51 ? 457 THR G O     1 
ATOM   14370 C CB    . THR G 3 487 ? 82.550  163.674 232.313 1.00 114.51 ? 457 THR G CB    1 
ATOM   14371 O OG1   . THR G 3 487 ? 82.048  162.976 231.165 1.00 114.51 ? 457 THR G OG1   1 
ATOM   14372 C CG2   . THR G 3 487 ? 83.367  162.690 233.158 1.00 114.51 ? 457 THR G CG2   1 
ATOM   14373 N N     . PRO G 3 488 ? 79.509  162.668 232.923 1.00 117.92 ? 458 PRO G N     1 
ATOM   14374 C CA    . PRO G 3 488 ? 78.738  161.520 233.409 1.00 117.92 ? 458 PRO G CA    1 
ATOM   14375 C C     . PRO G 3 488 ? 79.502  160.219 233.223 1.00 117.92 ? 458 PRO G C     1 
ATOM   14376 O O     . PRO G 3 488 ? 80.483  160.138 232.482 1.00 117.92 ? 458 PRO G O     1 
ATOM   14377 C CB    . PRO G 3 488 ? 77.467  161.540 232.545 1.00 117.92 ? 458 PRO G CB    1 
ATOM   14378 C CG    . PRO G 3 488 ? 77.601  162.737 231.648 1.00 117.92 ? 458 PRO G CG    1 
ATOM   14379 C CD    . PRO G 3 488 ? 79.058  162.995 231.557 1.00 117.92 ? 458 PRO G CD    1 
ATOM   14380 N N     . MET G 3 489 ? 79.018  159.182 233.911 1.00 118.07 ? 459 MET G N     1 
ATOM   14381 C CA    . MET G 3 489 ? 79.652  157.870 233.821 1.00 118.07 ? 459 MET G CA    1 
ATOM   14382 C C     . MET G 3 489 ? 79.534  157.267 232.425 1.00 118.07 ? 459 MET G C     1 
ATOM   14383 O O     . MET G 3 489 ? 80.364  156.431 232.046 1.00 118.07 ? 459 MET G O     1 
ATOM   14384 C CB    . MET G 3 489 ? 79.035  156.921 234.853 1.00 118.07 ? 459 MET G CB    1 
ATOM   14385 C CG    . MET G 3 489 ? 79.204  157.342 236.315 1.00 118.07 ? 459 MET G CG    1 
ATOM   14386 S SD    . MET G 3 489 ? 80.912  157.557 236.866 1.00 118.07 ? 459 MET G SD    1 
ATOM   14387 C CE    . MET G 3 489 ? 81.089  159.335 236.742 1.00 118.07 ? 459 MET G CE    1 
ATOM   14388 N N     . GLU G 3 490 ? 78.519  157.671 231.651 1.00 119.64 ? 460 GLU G N     1 
ATOM   14389 C CA    . GLU G 3 490 ? 78.310  157.107 230.319 1.00 119.64 ? 460 GLU G CA    1 
ATOM   14390 C C     . GLU G 3 490 ? 79.478  157.422 229.390 1.00 119.64 ? 460 GLU G C     1 
ATOM   14391 O O     . GLU G 3 490 ? 80.001  156.532 228.709 1.00 119.64 ? 460 GLU G O     1 
ATOM   14392 C CB    . GLU G 3 490 ? 76.999  157.638 229.739 1.00 119.64 ? 460 GLU G CB    1 
ATOM   14393 C CG    . GLU G 3 490 ? 75.765  157.228 230.533 1.00 119.64 ? 460 GLU G CG    1 
ATOM   14394 C CD    . GLU G 3 490 ? 74.478  157.756 229.931 1.00 119.64 ? 460 GLU G CD    1 
ATOM   14395 O OE1   . GLU G 3 490 ? 74.411  158.967 229.632 1.00 119.64 ? 460 GLU G OE1   1 
ATOM   14396 O OE2   . GLU G 3 490 ? 73.531  156.959 229.761 1.00 119.64 ? 460 GLU G OE2   1 
ATOM   14397 N N     . TYR G 3 491 ? 79.905  158.688 229.351 1.00 113.95 ? 461 TYR G N     1 
ATOM   14398 C CA    . TYR G 3 491 ? 81.095  159.058 228.590 1.00 113.95 ? 461 TYR G CA    1 
ATOM   14399 C C     . TYR G 3 491 ? 82.378  158.669 229.313 1.00 113.95 ? 461 TYR G C     1 
ATOM   14400 O O     . TYR G 3 491 ? 83.387  158.380 228.656 1.00 113.95 ? 461 TYR G O     1 
ATOM   14401 C CB    . TYR G 3 491 ? 81.106  160.566 228.315 1.00 113.95 ? 461 TYR G CB    1 
ATOM   14402 C CG    . TYR G 3 491 ? 79.902  161.116 227.563 1.00 113.95 ? 461 TYR G CG    1 
ATOM   14403 C CD1   . TYR G 3 491 ? 79.274  160.388 226.557 1.00 113.95 ? 461 TYR G CD1   1 
ATOM   14404 C CD2   . TYR G 3 491 ? 79.402  162.378 227.861 1.00 113.95 ? 461 TYR G CD2   1 
ATOM   14405 C CE1   . TYR G 3 491 ? 78.183  160.897 225.877 1.00 113.95 ? 461 TYR G CE1   1 
ATOM   14406 C CE2   . TYR G 3 491 ? 78.313  162.895 227.186 1.00 113.95 ? 461 TYR G CE2   1 
ATOM   14407 C CZ    . TYR G 3 491 ? 77.707  162.151 226.196 1.00 113.95 ? 461 TYR G CZ    1 
ATOM   14408 O OH    . TYR G 3 491 ? 76.621  162.663 225.523 1.00 113.95 ? 461 TYR G OH    1 
ATOM   14409 N N     . ALA G 3 492 ? 82.364  158.673 230.651 1.00 113.44 ? 462 ALA G N     1 
ATOM   14410 C CA    . ALA G 3 492 ? 83.575  158.376 231.411 1.00 113.44 ? 462 ALA G CA    1 
ATOM   14411 C C     . ALA G 3 492 ? 84.032  156.942 231.194 1.00 113.44 ? 462 ALA G C     1 
ATOM   14412 O O     . ALA G 3 492 ? 85.236  156.681 231.107 1.00 113.44 ? 462 ALA G O     1 
ATOM   14413 C CB    . ALA G 3 492 ? 83.344  158.627 232.900 1.00 113.44 ? 462 ALA G CB    1 
ATOM   14414 N N     . GLU G 3 493 ? 83.087  155.998 231.124 1.00 112.07 ? 463 GLU G N     1 
ATOM   14415 C CA    . GLU G 3 493 ? 83.452  154.600 230.910 1.00 112.07 ? 463 GLU G CA    1 
ATOM   14416 C C     . GLU G 3 493 ? 84.131  154.411 229.560 1.00 112.07 ? 463 GLU G C     1 
ATOM   14417 O O     . GLU G 3 493 ? 85.154  153.726 229.464 1.00 112.07 ? 463 GLU G O     1 
ATOM   14418 C CB    . GLU G 3 493 ? 82.207  153.715 231.019 1.00 112.07 ? 463 GLU G CB    1 
ATOM   14419 C CG    . GLU G 3 493 ? 82.483  152.210 231.132 1.00 112.07 ? 463 GLU G CG    1 
ATOM   14420 C CD    . GLU G 3 493 ? 83.116  151.808 232.456 1.00 112.07 ? 463 GLU G CD    1 
ATOM   14421 O OE1   . GLU G 3 493 ? 82.845  152.468 233.482 1.00 112.07 ? 463 GLU G OE1   1 
ATOM   14422 O OE2   . GLU G 3 493 ? 83.890  150.828 232.469 1.00 112.07 ? 463 GLU G OE2   1 
ATOM   14423 N N     . VAL G 3 494 ? 83.600  155.049 228.515 1.00 109.98 ? 464 VAL G N     1 
ATOM   14424 C CA    . VAL G 3 494 ? 84.196  154.926 227.188 1.00 109.98 ? 464 VAL G CA    1 
ATOM   14425 C C     . VAL G 3 494 ? 85.561  155.607 227.157 1.00 109.98 ? 464 VAL G C     1 
ATOM   14426 O O     . VAL G 3 494 ? 86.513  155.090 226.553 1.00 109.98 ? 464 VAL G O     1 
ATOM   14427 C CB    . VAL G 3 494 ? 83.246  155.494 226.110 1.00 109.98 ? 464 VAL G CB    1 
ATOM   14428 C CG1   . VAL G 3 494 ? 83.830  155.294 224.696 1.00 109.98 ? 464 VAL G CG1   1 
ATOM   14429 C CG2   . VAL G 3 494 ? 81.847  154.852 226.209 1.00 109.98 ? 464 VAL G CG2   1 
ATOM   14430 N N     . LEU G 3 495 ? 85.678  156.776 227.799 1.00 108.34 ? 465 LEU G N     1 
ATOM   14431 C CA    . LEU G 3 495 ? 86.958  157.481 227.802 1.00 108.34 ? 465 LEU G CA    1 
ATOM   14432 C C     . LEU G 3 495 ? 88.027  156.690 228.545 1.00 108.34 ? 465 LEU G C     1 
ATOM   14433 O O     . LEU G 3 495 ? 89.166  156.602 228.081 1.00 108.34 ? 465 LEU G O     1 
ATOM   14434 C CB    . LEU G 3 495 ? 86.823  158.877 228.424 1.00 108.34 ? 465 LEU G CB    1 
ATOM   14435 C CG    . LEU G 3 495 ? 86.611  160.107 227.520 1.00 108.34 ? 465 LEU G CG    1 
ATOM   14436 C CD1   . LEU G 3 495 ? 86.415  161.357 228.375 1.00 108.34 ? 465 LEU G CD1   1 
ATOM   14437 C CD2   . LEU G 3 495 ? 87.739  160.322 226.489 1.00 108.34 ? 465 LEU G CD2   1 
ATOM   14438 N N     . ASP G 3 496 ? 87.680  156.093 229.688 1.00 110.29 ? 466 ASP G N     1 
ATOM   14439 C CA    . ASP G 3 496 ? 88.651  155.279 230.412 1.00 110.29 ? 466 ASP G CA    1 
ATOM   14440 C C     . ASP G 3 496 ? 88.961  153.982 229.676 1.00 110.29 ? 466 ASP G C     1 
ATOM   14441 O O     . ASP G 3 496 ? 90.095  153.495 229.747 1.00 110.29 ? 466 ASP G O     1 
ATOM   14442 C CB    . ASP G 3 496 ? 88.150  154.989 231.826 1.00 110.29 ? 466 ASP G CB    1 
ATOM   14443 C CG    . ASP G 3 496 ? 87.799  156.251 232.587 1.00 110.29 ? 466 ASP G CG    1 
ATOM   14444 O OD1   . ASP G 3 496 ? 88.335  157.323 232.236 1.00 110.29 ? 466 ASP G OD1   1 
ATOM   14445 O OD2   . ASP G 3 496 ? 86.982  156.175 233.529 1.00 110.29 ? 466 ASP G OD2   1 
ATOM   14446 N N     . LYS G 3 497 ? 87.984  153.415 228.960 1.00 108.64 ? 467 LYS G N     1 
ATOM   14447 C CA    . LYS G 3 497 ? 88.257  152.227 228.153 1.00 108.64 ? 467 LYS G CA    1 
ATOM   14448 C C     . LYS G 3 497 ? 89.262  152.536 227.051 1.00 108.64 ? 467 LYS G C     1 
ATOM   14449 O O     . LYS G 3 497 ? 90.173  151.742 226.790 1.00 108.64 ? 467 LYS G O     1 
ATOM   14450 C CB    . LYS G 3 497 ? 86.966  151.670 227.541 1.00 108.64 ? 467 LYS G CB    1 
ATOM   14451 C CG    . LYS G 3 497 ? 86.528  150.325 228.108 1.00 108.64 ? 467 LYS G CG    1 
ATOM   14452 C CD    . LYS G 3 497 ? 86.121  150.415 229.573 1.00 108.64 ? 467 LYS G CD    1 
ATOM   14453 C CE    . LYS G 3 497 ? 85.650  149.068 230.097 1.00 108.64 ? 467 LYS G CE    1 
ATOM   14454 N NZ    . LYS G 3 497 ? 86.761  148.079 230.176 1.00 108.64 ? 467 LYS G NZ    1 
ATOM   14455 N N     . LEU G 3 498 ? 89.112  153.688 226.394 1.00 103.77 ? 468 LEU G N     1 
ATOM   14456 C CA    . LEU G 3 498 ? 90.084  154.080 225.378 1.00 103.77 ? 468 LEU G CA    1 
ATOM   14457 C C     . LEU G 3 498 ? 91.428  154.431 226.007 1.00 103.77 ? 468 LEU G C     1 
ATOM   14458 O O     . LEU G 3 498 ? 92.487  154.082 225.468 1.00 103.77 ? 468 LEU G O     1 
ATOM   14459 C CB    . LEU G 3 498 ? 89.540  155.257 224.567 1.00 103.77 ? 468 LEU G CB    1 
ATOM   14460 C CG    . LEU G 3 498 ? 88.322  154.929 223.685 1.00 103.77 ? 468 LEU G CG    1 
ATOM   14461 C CD1   . LEU G 3 498 ? 87.496  156.161 223.295 1.00 103.77 ? 468 LEU G CD1   1 
ATOM   14462 C CD2   . LEU G 3 498 ? 88.754  154.177 222.428 1.00 103.77 ? 468 LEU G CD2   1 
ATOM   14463 N N     . ARG G 3 499 ? 91.408  155.106 227.159 1.00 104.13 ? 469 ARG G N     1 
ATOM   14464 C CA    . ARG G 3 499 ? 92.643  155.525 227.804 1.00 104.13 ? 469 ARG G CA    1 
ATOM   14465 C C     . ARG G 3 499 ? 93.421  154.357 228.392 1.00 104.13 ? 469 ARG G C     1 
ATOM   14466 O O     . ARG G 3 499 ? 94.624  154.494 228.635 1.00 104.13 ? 469 ARG G O     1 
ATOM   14467 C CB    . ARG G 3 499 ? 92.343  156.550 228.898 1.00 104.13 ? 469 ARG G CB    1 
ATOM   14468 C CG    . ARG G 3 499 ? 93.547  157.392 229.350 1.00 104.13 ? 469 ARG G CG    1 
ATOM   14469 C CD    . ARG G 3 499 ? 94.180  158.285 228.265 1.00 104.13 ? 469 ARG G CD    1 
ATOM   14470 N NE    . ARG G 3 499 ? 93.204  158.892 227.364 1.00 104.13 ? 469 ARG G NE    1 
ATOM   14471 C CZ    . ARG G 3 499 ? 92.286  159.786 227.711 1.00 104.13 ? 469 ARG G CZ    1 
ATOM   14472 N NH1   . ARG G 3 499 ? 92.199  160.262 228.946 1.00 104.13 ? 469 ARG G NH1   1 
ATOM   14473 N NH2   . ARG G 3 499 ? 91.426  160.218 226.793 1.00 104.13 ? 469 ARG G NH2   1 
ATOM   14474 N N     . SER G 3 500 ? 92.760  153.226 228.646 1.00 105.26 ? 470 SER G N     1 
ATOM   14475 C CA    . SER G 3 500 ? 93.487  152.021 229.023 1.00 105.26 ? 470 SER G CA    1 
ATOM   14476 C C     . SER G 3 500 ? 94.438  151.581 227.919 1.00 105.26 ? 470 SER G C     1 
ATOM   14477 O O     . SER G 3 500 ? 95.528  151.074 228.210 1.00 105.26 ? 470 SER G O     1 
ATOM   14478 C CB    . SER G 3 500 ? 92.501  150.901 229.356 1.00 105.26 ? 470 SER G CB    1 
ATOM   14479 O OG    . SER G 3 500 ? 91.625  151.287 230.401 1.00 105.26 ? 470 SER G OG    1 
ATOM   14480 N N     . ARG G 3 501 ? 94.053  151.782 226.652 1.00 100.30 ? 471 ARG G N     1 
ATOM   14481 C CA    . ARG G 3 501 ? 94.863  151.388 225.504 1.00 100.30 ? 471 ARG G CA    1 
ATOM   14482 C C     . ARG G 3 501 ? 95.688  152.526 224.910 1.00 100.30 ? 471 ARG G C     1 
ATOM   14483 O O     . ARG G 3 501 ? 96.594  152.251 224.117 1.00 100.30 ? 471 ARG G O     1 
ATOM   14484 C CB    . ARG G 3 501 ? 93.975  150.773 224.411 1.00 100.30 ? 471 ARG G CB    1 
ATOM   14485 C CG    . ARG G 3 501 ? 93.160  149.559 224.907 1.00 100.30 ? 471 ARG G CG    1 
ATOM   14486 C CD    . ARG G 3 501 ? 92.258  148.895 223.867 1.00 100.30 ? 471 ARG G CD    1 
ATOM   14487 N NE    . ARG G 3 501 ? 92.474  149.338 222.487 1.00 100.30 ? 471 ARG G NE    1 
ATOM   14488 C CZ    . ARG G 3 501 ? 91.584  149.913 221.681 1.00 100.30 ? 471 ARG G CZ    1 
ATOM   14489 N NH1   . ARG G 3 501 ? 90.434  150.404 222.127 1.00 100.30 ? 471 ARG G NH1   1 
ATOM   14490 N NH2   . ARG G 3 501 ? 91.863  150.017 220.384 1.00 100.30 ? 471 ARG G NH2   1 
ATOM   14491 N N     . TYR G 3 502 ? 95.410  153.787 225.263 1.00 94.93  ? 472 TYR G N     1 
ATOM   14492 C CA    . TYR G 3 502 ? 96.268  154.882 224.802 1.00 94.93  ? 472 TYR G CA    1 
ATOM   14493 C C     . TYR G 3 502 ? 97.578  154.929 225.580 1.00 94.93  ? 472 TYR G C     1 
ATOM   14494 O O     . TYR G 3 502 ? 98.660  154.757 225.008 1.00 94.93  ? 472 TYR G O     1 
ATOM   14495 C CB    . TYR G 3 502 ? 95.565  156.233 224.942 1.00 94.93  ? 472 TYR G CB    1 
ATOM   14496 C CG    . TYR G 3 502 ? 94.881  156.741 223.701 1.00 94.93  ? 472 TYR G CG    1 
ATOM   14497 C CD1   . TYR G 3 502 ? 93.579  156.376 223.406 1.00 94.93  ? 472 TYR G CD1   1 
ATOM   14498 C CD2   . TYR G 3 502 ? 95.525  157.622 222.844 1.00 94.93  ? 472 TYR G CD2   1 
ATOM   14499 C CE1   . TYR G 3 502 ? 92.947  156.845 222.285 1.00 94.93  ? 472 TYR G CE1   1 
ATOM   14500 C CE2   . TYR G 3 502 ? 94.898  158.101 221.717 1.00 94.93  ? 472 TYR G CE2   1 
ATOM   14501 C CZ    . TYR G 3 502 ? 93.606  157.712 221.447 1.00 94.93  ? 472 TYR G CZ    1 
ATOM   14502 O OH    . TYR G 3 502 ? 92.966  158.177 220.331 1.00 94.93  ? 472 TYR G OH    1 
ATOM   14503 N N     . CYS G 3 503 ? 97.493  155.181 226.891 1.00 102.38 ? 473 CYS G N     1 
ATOM   14504 C CA    . CYS G 3 503 ? 98.693  155.412 227.689 1.00 102.38 ? 473 CYS G CA    1 
ATOM   14505 C C     . CYS G 3 503 ? 99.541  154.152 227.798 1.00 102.38 ? 473 CYS G C     1 
ATOM   14506 O O     . CYS G 3 503 ? 100.770 154.216 227.673 1.00 102.38 ? 473 CYS G O     1 
ATOM   14507 C CB    . CYS G 3 503 ? 98.309  155.916 229.080 1.00 102.38 ? 473 CYS G CB    1 
ATOM   14508 S SG    . CYS G 3 503 ? 97.806  154.613 230.227 1.00 102.38 ? 473 CYS G SG    1 
ATOM   14509 N N     . LEU G 3 504 ? 98.897  153.002 228.018 1.00 100.76 ? 474 LEU G N     1 
ATOM   14510 C CA    . LEU G 3 504 ? 99.572  151.706 228.123 1.00 100.76 ? 474 LEU G CA    1 
ATOM   14511 C C     . LEU G 3 504 ? 100.603 151.704 229.250 1.00 100.76 ? 474 LEU G C     1 
ATOM   14512 O O     . LEU G 3 504 ? 101.710 151.183 229.105 1.00 100.76 ? 474 LEU G O     1 
ATOM   14513 C CB    . LEU G 3 504 ? 100.219 151.312 226.790 1.00 100.76 ? 474 LEU G CB    1 
ATOM   14514 C CG    . LEU G 3 504 ? 99.282  151.236 225.574 1.00 100.76 ? 474 LEU G CG    1 
ATOM   14515 C CD1   . LEU G 3 504 ? 100.052 151.058 224.277 1.00 100.76 ? 474 LEU G CD1   1 
ATOM   14516 C CD2   . LEU G 3 504 ? 98.284  150.097 225.721 1.00 100.76 ? 474 LEU G CD2   1 
ATOM   14517 N N     . LYS G 3 505 ? 100.238 152.312 230.378 1.00 107.77 ? 475 LYS G N     1 
ATOM   14518 C CA    . LYS G 3 505 ? 101.112 152.326 231.543 1.00 107.77 ? 475 LYS G CA    1 
ATOM   14519 C C     . LYS G 3 505 ? 101.293 150.908 232.073 1.00 107.77 ? 475 LYS G C     1 
ATOM   14520 O O     . LYS G 3 505 ? 100.323 150.159 232.226 1.00 107.77 ? 475 LYS G O     1 
ATOM   14521 C CB    . LYS G 3 505 ? 100.522 153.238 232.622 1.00 107.77 ? 475 LYS G CB    1 
ATOM   14522 C CG    . LYS G 3 505 ? 101.365 153.384 233.888 1.00 107.77 ? 475 LYS G CG    1 
ATOM   14523 C CD    . LYS G 3 505 ? 100.754 154.401 234.841 1.00 107.77 ? 475 LYS G CD    1 
ATOM   14524 C CE    . LYS G 3 505 ? 101.199 155.819 234.516 1.00 107.77 ? 475 LYS G CE    1 
ATOM   14525 N NZ    . LYS G 3 505 ? 102.559 156.114 235.045 1.00 107.77 ? 475 LYS G NZ    1 
ATOM   14526 N N     . GLN G 3 506 ? 102.539 150.541 232.350 1.00 113.83 ? 476 GLN G N     1 
ATOM   14527 C CA    . GLN G 3 506 ? 102.855 149.197 232.821 1.00 113.83 ? 476 GLN G CA    1 
ATOM   14528 C C     . GLN G 3 506 ? 104.241 149.157 233.454 1.00 113.83 ? 476 GLN G C     1 
ATOM   14529 O O     . GLN G 3 506 ? 105.100 149.986 233.156 1.00 113.83 ? 476 GLN G O     1 
ATOM   14530 C CB    . GLN G 3 506 ? 102.772 148.187 231.671 1.00 113.83 ? 476 GLN G CB    1 
ATOM   14531 C CG    . GLN G 3 506 ? 103.824 148.376 230.583 1.00 113.83 ? 476 GLN G CG    1 
ATOM   14532 C CD    . GLN G 3 506 ? 103.406 147.766 229.259 1.00 113.83 ? 476 GLN G CD    1 
ATOM   14533 O OE1   . GLN G 3 506 ? 103.644 146.586 229.003 1.00 113.83 ? 476 GLN G OE1   1 
ATOM   14534 N NE2   . GLN G 3 506 ? 102.779 148.571 228.409 1.00 113.83 ? 476 GLN G NE2   1 
HETATM 14535 P PB    . ADP H 4 .   ? 111.907 173.126 193.552 1.00 32.86  ? 501 ADP A PB    1 
HETATM 14536 O O1B   . ADP H 4 .   ? 111.388 174.090 192.521 1.00 32.86  ? 501 ADP A O1B   1 
HETATM 14537 O O2B   . ADP H 4 .   ? 112.965 172.238 193.006 1.00 32.86  ? 501 ADP A O2B   1 
HETATM 14538 O O3B   . ADP H 4 .   ? 110.834 172.351 194.256 1.00 32.86  ? 501 ADP A O3B   1 
HETATM 14539 P PA    . ADP H 4 .   ? 113.349 175.426 194.480 1.00 32.86  ? 501 ADP A PA    1 
HETATM 14540 O O1A   . ADP H 4 .   ? 113.859 175.469 193.081 1.00 32.86  ? 501 ADP A O1A   1 
HETATM 14541 O O2A   . ADP H 4 .   ? 114.299 175.616 195.611 1.00 32.86  ? 501 ADP A O2A   1 
HETATM 14542 O O3A   . ADP H 4 .   ? 112.597 174.033 194.674 1.00 32.86  ? 501 ADP A O3A   1 
HETATM 14543 O "O5'" . ADP H 4 .   ? 112.133 176.456 194.635 1.00 32.86  ? 501 ADP A "O5'" 1 
HETATM 14544 C "C5'" . ADP H 4 .   ? 112.023 177.637 193.795 1.00 32.86  ? 501 ADP A "C5'" 1 
HETATM 14545 C "C4'" . ADP H 4 .   ? 112.709 178.802 194.461 1.00 32.86  ? 501 ADP A "C4'" 1 
HETATM 14546 O "O4'" . ADP H 4 .   ? 112.347 178.830 195.858 1.00 32.86  ? 501 ADP A "O4'" 1 
HETATM 14547 C "C3'" . ADP H 4 .   ? 114.239 178.780 194.466 1.00 32.86  ? 501 ADP A "C3'" 1 
HETATM 14548 O "O3'" . ADP H 4 .   ? 114.727 179.435 193.306 1.00 32.86  ? 501 ADP A "O3'" 1 
HETATM 14549 C "C2'" . ADP H 4 .   ? 114.611 179.538 195.743 1.00 32.86  ? 501 ADP A "C2'" 1 
HETATM 14550 O "O2'" . ADP H 4 .   ? 114.981 180.866 195.454 1.00 32.86  ? 501 ADP A "O2'" 1 
HETATM 14551 C "C1'" . ADP H 4 .   ? 113.334 179.527 196.580 1.00 32.86  ? 501 ADP A "C1'" 1 
HETATM 14552 N N9    . ADP H 4 .   ? 113.474 178.860 197.867 1.00 32.86  ? 501 ADP A N9    1 
HETATM 14553 C C8    . ADP H 4 .   ? 113.090 177.577 198.157 1.00 32.86  ? 501 ADP A C8    1 
HETATM 14554 N N7    . ADP H 4 .   ? 113.325 177.234 199.395 1.00 32.86  ? 501 ADP A N7    1 
HETATM 14555 C C5    . ADP H 4 .   ? 113.909 178.355 199.957 1.00 32.86  ? 501 ADP A C5    1 
HETATM 14556 C C6    . ADP H 4 .   ? 114.387 178.611 201.251 1.00 32.86  ? 501 ADP A C6    1 
HETATM 14557 N N6    . ADP H 4 .   ? 114.348 177.721 202.236 1.00 32.86  ? 501 ADP A N6    1 
HETATM 14558 N N1    . ADP H 4 .   ? 114.915 179.833 201.488 1.00 32.86  ? 501 ADP A N1    1 
HETATM 14559 C C2    . ADP H 4 .   ? 114.946 180.718 200.487 1.00 32.86  ? 501 ADP A C2    1 
HETATM 14560 N N3    . ADP H 4 .   ? 114.525 180.587 199.234 1.00 32.86  ? 501 ADP A N3    1 
HETATM 14561 C C4    . ADP H 4 .   ? 114.009 179.366 199.026 1.00 32.86  ? 501 ADP A C4    1 
HETATM 14562 P PB    . ADP I 4 .   ? 84.815  162.745 142.596 1.00 42.73  ? 501 ADP C PB    1 
HETATM 14563 O O1B   . ADP I 4 .   ? 86.141  163.416 142.410 1.00 42.73  ? 501 ADP C O1B   1 
HETATM 14564 O O2B   . ADP I 4 .   ? 84.863  161.637 143.609 1.00 42.73  ? 501 ADP C O2B   1 
HETATM 14565 O O3B   . ADP I 4 .   ? 83.722  163.717 142.871 1.00 42.73  ? 501 ADP C O3B   1 
HETATM 14566 P PA    . ADP I 4 .   ? 83.700  162.698 139.906 1.00 42.73  ? 501 ADP C PA    1 
HETATM 14567 O O1A   . ADP I 4 .   ? 84.397  163.968 139.569 1.00 42.73  ? 501 ADP C O1A   1 
HETATM 14568 O O2A   . ADP I 4 .   ? 82.237  162.722 140.174 1.00 42.73  ? 501 ADP C O2A   1 
HETATM 14569 O O3A   . ADP I 4 .   ? 84.446  162.078 141.178 1.00 42.73  ? 501 ADP C O3A   1 
HETATM 14570 O "O5'" . ADP I 4 .   ? 83.981  161.624 138.756 1.00 42.73  ? 501 ADP C "O5'" 1 
HETATM 14571 C "C5'" . ADP I 4 .   ? 83.011  160.566 138.531 1.00 42.73  ? 501 ADP C "C5'" 1 
HETATM 14572 C "C4'" . ADP I 4 .   ? 82.156  160.894 137.332 1.00 42.73  ? 501 ADP C "C4'" 1 
HETATM 14573 O "O4'" . ADP I 4 .   ? 81.255  161.987 137.649 1.00 42.73  ? 501 ADP C "O4'" 1 
HETATM 14574 C "C3'" . ADP I 4 .   ? 82.918  161.345 136.077 1.00 42.73  ? 501 ADP C "C3'" 1 
HETATM 14575 O "O3'" . ADP I 4 .   ? 82.418  160.669 134.933 1.00 42.73  ? 501 ADP C "O3'" 1 
HETATM 14576 C "C2'" . ADP I 4 .   ? 82.606  162.841 136.017 1.00 42.73  ? 501 ADP C "C2'" 1 
HETATM 14577 O "O2'" . ADP I 4 .   ? 82.697  163.396 134.726 1.00 42.73  ? 501 ADP C "O2'" 1 
HETATM 14578 C "C1'" . ADP I 4 .   ? 81.173  162.806 136.511 1.00 42.73  ? 501 ADP C "C1'" 1 
HETATM 14579 N N9    . ADP I 4 .   ? 80.630  164.107 136.867 1.00 42.73  ? 501 ADP C N9    1 
HETATM 14580 C C8    . ADP I 4 .   ? 80.436  164.600 138.129 1.00 42.73  ? 501 ADP C C8    1 
HETATM 14581 N N7    . ADP I 4 .   ? 79.941  165.808 138.137 1.00 42.73  ? 501 ADP C N7    1 
HETATM 14582 C C5    . ADP I 4 .   ? 79.797  166.141 136.805 1.00 42.73  ? 501 ADP C C5    1 
HETATM 14583 C C6    . ADP I 4 .   ? 79.317  167.297 136.167 1.00 42.73  ? 501 ADP C C6    1 
HETATM 14584 N N6    . ADP I 4 .   ? 78.871  168.367 136.816 1.00 42.73  ? 501 ADP C N6    1 
HETATM 14585 N N1    . ADP I 4 .   ? 79.315  167.308 134.816 1.00 42.73  ? 501 ADP C N1    1 
HETATM 14586 C C2    . ADP I 4 .   ? 79.771  166.228 134.173 1.00 42.73  ? 501 ADP C C2    1 
HETATM 14587 N N3    . ADP I 4 .   ? 80.236  165.086 134.671 1.00 42.73  ? 501 ADP C N3    1 
HETATM 14588 C C4    . ADP I 4 .   ? 80.230  165.104 136.009 1.00 42.73  ? 501 ADP C C4    1 
HETATM 14589 P PB    . ADP J 4 .   ? 99.251  118.409 176.904 1.00 36.24  ? 501 ADP B PB    1 
HETATM 14590 O O1B   . ADP J 4 .   ? 99.763  117.596 175.745 1.00 36.24  ? 501 ADP B O1B   1 
HETATM 14591 O O2B   . ADP J 4 .   ? 99.731  119.839 176.923 1.00 36.24  ? 501 ADP B O2B   1 
HETATM 14592 O O3B   . ADP J 4 .   ? 97.775  118.260 177.164 1.00 36.24  ? 501 ADP B O3B   1 
HETATM 14593 P PA    . ADP J 4 .   ? 99.683  116.192 178.551 1.00 36.24  ? 501 ADP B PA    1 
HETATM 14594 O O1A   . ADP J 4 .   ? 100.443 115.323 177.584 1.00 36.24  ? 501 ADP B O1A   1 
HETATM 14595 O O2A   . ADP J 4 .   ? 98.189  116.029 178.654 1.00 36.24  ? 501 ADP B O2A   1 
HETATM 14596 O O3A   . ADP J 4 .   ? 99.956  117.733 178.182 1.00 36.24  ? 501 ADP B O3A   1 
HETATM 14597 O "O5'" . ADP J 4 .   ? 100.376 116.028 180.000 1.00 36.24  ? 501 ADP B "O5'" 1 
HETATM 14598 C "C5'" . ADP J 4 .   ? 99.794  115.279 181.074 1.00 36.24  ? 501 ADP B "C5'" 1 
HETATM 14599 C "C4'" . ADP J 4 .   ? 100.574 114.021 181.474 1.00 36.24  ? 501 ADP B "C4'" 1 
HETATM 14600 O "O4'" . ADP J 4 .   ? 99.637  112.985 181.786 1.00 36.24  ? 501 ADP B "O4'" 1 
HETATM 14601 C "C3'" . ADP J 4 .   ? 101.533 113.436 180.447 1.00 36.24  ? 501 ADP B "C3'" 1 
HETATM 14602 O "O3'" . ADP J 4 .   ? 102.868 113.731 180.859 1.00 36.24  ? 501 ADP B "O3'" 1 
HETATM 14603 C "C2'" . ADP J 4 .   ? 101.285 111.943 180.436 1.00 36.24  ? 501 ADP B "C2'" 1 
HETATM 14604 O "O2'" . ADP J 4 .   ? 102.363 111.260 181.079 1.00 36.24  ? 501 ADP B "O2'" 1 
HETATM 14605 C "C1'" . ADP J 4 .   ? 100.003 111.727 181.213 1.00 36.24  ? 501 ADP B "C1'" 1 
HETATM 14606 N N9    . ADP J 4 .   ? 98.888  111.281 180.341 1.00 36.24  ? 501 ADP B N9    1 
HETATM 14607 C C8    . ADP J 4 .   ? 98.151  112.111 179.582 1.00 36.24  ? 501 ADP B C8    1 
HETATM 14608 N N7    . ADP J 4 .   ? 97.197  111.434 178.907 1.00 36.24  ? 501 ADP B N7    1 
HETATM 14609 C C5    . ADP J 4 .   ? 97.313  110.143 179.231 1.00 36.24  ? 501 ADP B C5    1 
HETATM 14610 C C6    . ADP J 4 .   ? 96.599  108.911 178.858 1.00 36.24  ? 501 ADP B C6    1 
HETATM 14611 N N6    . ADP J 4 .   ? 95.565  108.945 177.986 1.00 36.24  ? 501 ADP B N6    1 
HETATM 14612 N N1    . ADP J 4 .   ? 97.013  107.760 179.415 1.00 36.24  ? 501 ADP B N1    1 
HETATM 14613 C C2    . ADP J 4 .   ? 98.042  107.718 180.274 1.00 36.24  ? 501 ADP B C2    1 
HETATM 14614 N N3    . ADP J 4 .   ? 98.731  108.810 180.657 1.00 36.24  ? 501 ADP B N3    1 
HETATM 14615 C C4    . ADP J 4 .   ? 98.424  110.037 180.180 1.00 36.24  ? 501 ADP B C4    1 
# 
