data_9EP5
# 
_entry.id   9EP5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EP5         pdb_00009ep5 10.2210/pdb9ep5/pdb 
WWPDB D_1292136118 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-23 ? 
2 'Structure model' 1 1 2025-05-14 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EP5 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              keith.wilson@york.ac.uk 
_pdbx_contact_author.name_first         Keith 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            S 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3581-2194 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Roth, C.'        1  ? 
'Moroz, O.V.'     2  ? 
'Miranda, S.A.D.' 3  ? 
'Jahn, L.'        4  ? 
'Blagova, E.'     5  ? 
'Lebedev, A.A.'   6  ? 
'Segura, D.R.'    7  ? 
'Stringer, M.A.'  8  ? 
'Friis, E.P.'     9  ? 
'Davies, G.J.'    10 ? 
'Wilson, K.S.'    11 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acta Crystallogr D Struct Biol' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2059-7983 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            81 
_citation.language                  ? 
_citation.page_first                234 
_citation.page_last                 251 
_citation.title                     
'Structures of alpha-galactosaminidases from the CAZy GH114 family and homologs defining a new GH191 family of glycosidases.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S2059798325002864 
_citation.pdbx_database_id_PubMed   40232846 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Roth, C.'             1  ? 
primary 'Moroz, O.V.'          2  ? 
primary 'Miranda, S.A.D.'      3  ? 
primary 'Jahn, L.'             4  ? 
primary 'Blagova, E.V.'        5  ? 
primary 'Lebedev, A.A.'        6  ? 
primary 'Segura, D.R.'         7  ? 
primary 'Stringer, M.A.'       8  ? 
primary 'Friis, E.P.'          9  ? 
primary 'Franco Cairo, J.P.L.' 10 ? 
primary 'Davies, G.J.'         11 ? 
primary 'Wilson, K.S.'         12 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein' 32791.359 2   ? ? ? 
;This entry is a periodic representation of an aperiodic partially disordered crystal, in which chain D has occupancy 1/3 and overlaps with its symmetry equivalent. The minimal periodic representation without overlaps has a three times larger unit cell and contains two additional chains B and C related to A by translation. In the latter representation, the chain D has occupancy 1 but the completeness of data is 1/3.
;
2 non-polymer syn 'SULFATE ION'                                                           96.063    2   ? ? ? ? 
3 water       nat water                                                                   18.015    464 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;DAGTPTDAGTPTDAGTPTDAGTPTDAGTQVPWSNVKSFTYQLTNYPQGKLDAIAASKFDLAIVELVRDGSSGYFTAAEIS
ALKARGKQVLAYFEIGAIEEYRPEWSQVPADLKLGPVSGWPDEQYVKYWDERWWPIVQGRIDRALAAGFNGCYLDMVVTY
EEIPANSAGTNRADLARKMVALIARINTYAKARNPDFKVVPQNSPELVDDPAYLPAIDGLGMEDMYWSDDVACDEGWCEE
NRTNAARVRAAGKLVLSTDYATQSAHVADAYTRSRAAGFVPYVTVRALDRVTVNAGWDPQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;DAGTPTDAGTPTDAGTPTDAGTPTDAGTQVPWSNVKSFTYQLTNYPQGKLDAIAASKFDLAIVELVRDGSSGYFTAAEIS
ALKARGKQVLAYFEIGAIEEYRPEWSQVPADLKLGPVSGWPDEQYVKYWDERWWPIVQGRIDRALAAGFNGCYLDMVVTY
EEIPANSAGTNRADLARKMVALIARINTYAKARNPDFKVVPQNSPELVDDPAYLPAIDGLGMEDMYWSDDVACDEGWCEE
NRTNAARVRAAGKLVLSTDYATQSAHVADAYTRSRAAGFVPYVTVRALDRVTVNAGWDPQ
;
_entity_poly.pdbx_strand_id                 A,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   ALA n 
1 3   GLY n 
1 4   THR n 
1 5   PRO n 
1 6   THR n 
1 7   ASP n 
1 8   ALA n 
1 9   GLY n 
1 10  THR n 
1 11  PRO n 
1 12  THR n 
1 13  ASP n 
1 14  ALA n 
1 15  GLY n 
1 16  THR n 
1 17  PRO n 
1 18  THR n 
1 19  ASP n 
1 20  ALA n 
1 21  GLY n 
1 22  THR n 
1 23  PRO n 
1 24  THR n 
1 25  ASP n 
1 26  ALA n 
1 27  GLY n 
1 28  THR n 
1 29  GLN n 
1 30  VAL n 
1 31  PRO n 
1 32  TRP n 
1 33  SER n 
1 34  ASN n 
1 35  VAL n 
1 36  LYS n 
1 37  SER n 
1 38  PHE n 
1 39  THR n 
1 40  TYR n 
1 41  GLN n 
1 42  LEU n 
1 43  THR n 
1 44  ASN n 
1 45  TYR n 
1 46  PRO n 
1 47  GLN n 
1 48  GLY n 
1 49  LYS n 
1 50  LEU n 
1 51  ASP n 
1 52  ALA n 
1 53  ILE n 
1 54  ALA n 
1 55  ALA n 
1 56  SER n 
1 57  LYS n 
1 58  PHE n 
1 59  ASP n 
1 60  LEU n 
1 61  ALA n 
1 62  ILE n 
1 63  VAL n 
1 64  GLU n 
1 65  LEU n 
1 66  VAL n 
1 67  ARG n 
1 68  ASP n 
1 69  GLY n 
1 70  SER n 
1 71  SER n 
1 72  GLY n 
1 73  TYR n 
1 74  PHE n 
1 75  THR n 
1 76  ALA n 
1 77  ALA n 
1 78  GLU n 
1 79  ILE n 
1 80  SER n 
1 81  ALA n 
1 82  LEU n 
1 83  LYS n 
1 84  ALA n 
1 85  ARG n 
1 86  GLY n 
1 87  LYS n 
1 88  GLN n 
1 89  VAL n 
1 90  LEU n 
1 91  ALA n 
1 92  TYR n 
1 93  PHE n 
1 94  GLU n 
1 95  ILE n 
1 96  GLY n 
1 97  ALA n 
1 98  ILE n 
1 99  GLU n 
1 100 GLU n 
1 101 TYR n 
1 102 ARG n 
1 103 PRO n 
1 104 GLU n 
1 105 TRP n 
1 106 SER n 
1 107 GLN n 
1 108 VAL n 
1 109 PRO n 
1 110 ALA n 
1 111 ASP n 
1 112 LEU n 
1 113 LYS n 
1 114 LEU n 
1 115 GLY n 
1 116 PRO n 
1 117 VAL n 
1 118 SER n 
1 119 GLY n 
1 120 TRP n 
1 121 PRO n 
1 122 ASP n 
1 123 GLU n 
1 124 GLN n 
1 125 TYR n 
1 126 VAL n 
1 127 LYS n 
1 128 TYR n 
1 129 TRP n 
1 130 ASP n 
1 131 GLU n 
1 132 ARG n 
1 133 TRP n 
1 134 TRP n 
1 135 PRO n 
1 136 ILE n 
1 137 VAL n 
1 138 GLN n 
1 139 GLY n 
1 140 ARG n 
1 141 ILE n 
1 142 ASP n 
1 143 ARG n 
1 144 ALA n 
1 145 LEU n 
1 146 ALA n 
1 147 ALA n 
1 148 GLY n 
1 149 PHE n 
1 150 ASN n 
1 151 GLY n 
1 152 CYS n 
1 153 TYR n 
1 154 LEU n 
1 155 ASP n 
1 156 MET n 
1 157 VAL n 
1 158 VAL n 
1 159 THR n 
1 160 TYR n 
1 161 GLU n 
1 162 GLU n 
1 163 ILE n 
1 164 PRO n 
1 165 ALA n 
1 166 ASN n 
1 167 SER n 
1 168 ALA n 
1 169 GLY n 
1 170 THR n 
1 171 ASN n 
1 172 ARG n 
1 173 ALA n 
1 174 ASP n 
1 175 LEU n 
1 176 ALA n 
1 177 ARG n 
1 178 LYS n 
1 179 MET n 
1 180 VAL n 
1 181 ALA n 
1 182 LEU n 
1 183 ILE n 
1 184 ALA n 
1 185 ARG n 
1 186 ILE n 
1 187 ASN n 
1 188 THR n 
1 189 TYR n 
1 190 ALA n 
1 191 LYS n 
1 192 ALA n 
1 193 ARG n 
1 194 ASN n 
1 195 PRO n 
1 196 ASP n 
1 197 PHE n 
1 198 LYS n 
1 199 VAL n 
1 200 VAL n 
1 201 PRO n 
1 202 GLN n 
1 203 ASN n 
1 204 SER n 
1 205 PRO n 
1 206 GLU n 
1 207 LEU n 
1 208 VAL n 
1 209 ASP n 
1 210 ASP n 
1 211 PRO n 
1 212 ALA n 
1 213 TYR n 
1 214 LEU n 
1 215 PRO n 
1 216 ALA n 
1 217 ILE n 
1 218 ASP n 
1 219 GLY n 
1 220 LEU n 
1 221 GLY n 
1 222 MET n 
1 223 GLU n 
1 224 ASP n 
1 225 MET n 
1 226 TYR n 
1 227 TRP n 
1 228 SER n 
1 229 ASP n 
1 230 ASP n 
1 231 VAL n 
1 232 ALA n 
1 233 CYS n 
1 234 ASP n 
1 235 GLU n 
1 236 GLY n 
1 237 TRP n 
1 238 CYS n 
1 239 GLU n 
1 240 GLU n 
1 241 ASN n 
1 242 ARG n 
1 243 THR n 
1 244 ASN n 
1 245 ALA n 
1 246 ALA n 
1 247 ARG n 
1 248 VAL n 
1 249 ARG n 
1 250 ALA n 
1 251 ALA n 
1 252 GLY n 
1 253 LYS n 
1 254 LEU n 
1 255 VAL n 
1 256 LEU n 
1 257 SER n 
1 258 THR n 
1 259 ASP n 
1 260 TYR n 
1 261 ALA n 
1 262 THR n 
1 263 GLN n 
1 264 SER n 
1 265 ALA n 
1 266 HIS n 
1 267 VAL n 
1 268 ALA n 
1 269 ASP n 
1 270 ALA n 
1 271 TYR n 
1 272 THR n 
1 273 ARG n 
1 274 SER n 
1 275 ARG n 
1 276 ALA n 
1 277 ALA n 
1 278 GLY n 
1 279 PHE n 
1 280 VAL n 
1 281 PRO n 
1 282 TYR n 
1 283 VAL n 
1 284 THR n 
1 285 VAL n 
1 286 ARG n 
1 287 ALA n 
1 288 LEU n 
1 289 ASP n 
1 290 ARG n 
1 291 VAL n 
1 292 THR n 
1 293 VAL n 
1 294 ASN n 
1 295 ALA n 
1 296 GLY n 
1 297 TRP n 
1 298 ASP n 
1 299 PRO n 
1 300 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   300 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'environmental samples' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     321930 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Bacillus subtilis' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     1423 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   169 ?   ?   ?   A . n 
A 1 2   ALA 2   170 ?   ?   ?   A . n 
A 1 3   GLY 3   171 ?   ?   ?   A . n 
A 1 4   THR 4   172 ?   ?   ?   A . n 
A 1 5   PRO 5   173 ?   ?   ?   A . n 
A 1 6   THR 6   174 ?   ?   ?   A . n 
A 1 7   ASP 7   175 ?   ?   ?   A . n 
A 1 8   ALA 8   176 ?   ?   ?   A . n 
A 1 9   GLY 9   177 ?   ?   ?   A . n 
A 1 10  THR 10  178 ?   ?   ?   A . n 
A 1 11  PRO 11  179 ?   ?   ?   A . n 
A 1 12  THR 12  180 ?   ?   ?   A . n 
A 1 13  ASP 13  181 ?   ?   ?   A . n 
A 1 14  ALA 14  182 ?   ?   ?   A . n 
A 1 15  GLY 15  183 ?   ?   ?   A . n 
A 1 16  THR 16  184 ?   ?   ?   A . n 
A 1 17  PRO 17  185 ?   ?   ?   A . n 
A 1 18  THR 18  186 ?   ?   ?   A . n 
A 1 19  ASP 19  187 ?   ?   ?   A . n 
A 1 20  ALA 20  188 ?   ?   ?   A . n 
A 1 21  GLY 21  189 ?   ?   ?   A . n 
A 1 22  THR 22  190 ?   ?   ?   A . n 
A 1 23  PRO 23  191 ?   ?   ?   A . n 
A 1 24  THR 24  192 ?   ?   ?   A . n 
A 1 25  ASP 25  193 ?   ?   ?   A . n 
A 1 26  ALA 26  194 ?   ?   ?   A . n 
A 1 27  GLY 27  195 ?   ?   ?   A . n 
A 1 28  THR 28  196 ?   ?   ?   A . n 
A 1 29  GLN 29  197 185 GLN GLN A . n 
A 1 30  VAL 30  198 186 VAL VAL A . n 
A 1 31  PRO 31  199 187 PRO PRO A . n 
A 1 32  TRP 32  200 188 TRP TRP A . n 
A 1 33  SER 33  201 189 SER SER A . n 
A 1 34  ASN 34  202 190 ASN ASN A . n 
A 1 35  VAL 35  203 191 VAL VAL A . n 
A 1 36  LYS 36  204 192 LYS LYS A . n 
A 1 37  SER 37  205 193 SER SER A . n 
A 1 38  PHE 38  206 194 PHE PHE A . n 
A 1 39  THR 39  207 195 THR THR A . n 
A 1 40  TYR 40  208 196 TYR TYR A . n 
A 1 41  GLN 41  209 197 GLN GLN A . n 
A 1 42  LEU 42  210 198 LEU LEU A . n 
A 1 43  THR 43  211 199 THR THR A . n 
A 1 44  ASN 44  212 200 ASN ASN A . n 
A 1 45  TYR 45  213 201 TYR TYR A . n 
A 1 46  PRO 46  214 202 PRO PRO A . n 
A 1 47  GLN 47  215 203 GLN GLN A . n 
A 1 48  GLY 48  216 204 GLY GLY A . n 
A 1 49  LYS 49  217 205 LYS LYS A . n 
A 1 50  LEU 50  218 206 LEU LEU A . n 
A 1 51  ASP 51  219 207 ASP ASP A . n 
A 1 52  ALA 52  220 208 ALA ALA A . n 
A 1 53  ILE 53  221 209 ILE ILE A . n 
A 1 54  ALA 54  222 210 ALA ALA A . n 
A 1 55  ALA 55  223 211 ALA ALA A . n 
A 1 56  SER 56  224 212 SER SER A . n 
A 1 57  LYS 57  225 213 LYS LYS A . n 
A 1 58  PHE 58  226 214 PHE PHE A . n 
A 1 59  ASP 59  227 215 ASP ASP A . n 
A 1 60  LEU 60  228 216 LEU LEU A . n 
A 1 61  ALA 61  229 217 ALA ALA A . n 
A 1 62  ILE 62  230 218 ILE ILE A . n 
A 1 63  VAL 63  231 219 VAL VAL A . n 
A 1 64  GLU 64  232 220 GLU GLU A . n 
A 1 65  LEU 65  233 221 LEU LEU A . n 
A 1 66  VAL 66  234 222 VAL VAL A . n 
A 1 67  ARG 67  235 223 ARG ARG A . n 
A 1 68  ASP 68  236 224 ASP ASP A . n 
A 1 69  GLY 69  237 225 GLY GLY A . n 
A 1 70  SER 70  238 226 SER SER A . n 
A 1 71  SER 71  239 227 SER SER A . n 
A 1 72  GLY 72  240 228 GLY GLY A . n 
A 1 73  TYR 73  241 229 TYR TYR A . n 
A 1 74  PHE 74  242 230 PHE PHE A . n 
A 1 75  THR 75  243 231 THR THR A . n 
A 1 76  ALA 76  244 232 ALA ALA A . n 
A 1 77  ALA 77  245 233 ALA ALA A . n 
A 1 78  GLU 78  246 234 GLU GLU A . n 
A 1 79  ILE 79  247 235 ILE ILE A . n 
A 1 80  SER 80  248 236 SER SER A . n 
A 1 81  ALA 81  249 237 ALA ALA A . n 
A 1 82  LEU 82  250 238 LEU LEU A . n 
A 1 83  LYS 83  251 239 LYS LYS A . n 
A 1 84  ALA 84  252 240 ALA ALA A . n 
A 1 85  ARG 85  253 241 ARG ARG A . n 
A 1 86  GLY 86  254 242 GLY GLY A . n 
A 1 87  LYS 87  255 243 LYS LYS A . n 
A 1 88  GLN 88  256 244 GLN GLN A . n 
A 1 89  VAL 89  257 245 VAL VAL A . n 
A 1 90  LEU 90  258 246 LEU LEU A . n 
A 1 91  ALA 91  259 247 ALA ALA A . n 
A 1 92  TYR 92  260 248 TYR TYR A . n 
A 1 93  PHE 93  261 249 PHE PHE A . n 
A 1 94  GLU 94  262 250 GLU GLU A . n 
A 1 95  ILE 95  263 251 ILE ILE A . n 
A 1 96  GLY 96  264 252 GLY GLY A . n 
A 1 97  ALA 97  265 253 ALA ALA A . n 
A 1 98  ILE 98  266 254 ILE ILE A . n 
A 1 99  GLU 99  267 255 GLU GLU A . n 
A 1 100 GLU 100 268 256 GLU GLU A . n 
A 1 101 TYR 101 269 257 TYR TYR A . n 
A 1 102 ARG 102 270 258 ARG ARG A . n 
A 1 103 PRO 103 271 259 PRO PRO A . n 
A 1 104 GLU 104 272 260 GLU GLU A . n 
A 1 105 TRP 105 273 261 TRP TRP A . n 
A 1 106 SER 106 274 262 SER SER A . n 
A 1 107 GLN 107 275 263 GLN GLN A . n 
A 1 108 VAL 108 276 264 VAL VAL A . n 
A 1 109 PRO 109 277 265 PRO PRO A . n 
A 1 110 ALA 110 278 266 ALA ALA A . n 
A 1 111 ASP 111 279 267 ASP ASP A . n 
A 1 112 LEU 112 280 268 LEU LEU A . n 
A 1 113 LYS 113 281 269 LYS LYS A . n 
A 1 114 LEU 114 282 270 LEU LEU A . n 
A 1 115 GLY 115 283 271 GLY GLY A . n 
A 1 116 PRO 116 284 272 PRO PRO A . n 
A 1 117 VAL 117 285 273 VAL VAL A . n 
A 1 118 SER 118 286 274 SER SER A . n 
A 1 119 GLY 119 287 275 GLY GLY A . n 
A 1 120 TRP 120 288 276 TRP TRP A . n 
A 1 121 PRO 121 289 277 PRO PRO A . n 
A 1 122 ASP 122 290 278 ASP ASP A . n 
A 1 123 GLU 123 291 279 GLU GLU A . n 
A 1 124 GLN 124 292 280 GLN GLN A . n 
A 1 125 TYR 125 293 281 TYR TYR A . n 
A 1 126 VAL 126 294 282 VAL VAL A . n 
A 1 127 LYS 127 295 283 LYS LYS A . n 
A 1 128 TYR 128 296 284 TYR TYR A . n 
A 1 129 TRP 129 297 285 TRP TRP A . n 
A 1 130 ASP 130 298 286 ASP ASP A . n 
A 1 131 GLU 131 299 287 GLU GLU A . n 
A 1 132 ARG 132 300 288 ARG ARG A . n 
A 1 133 TRP 133 301 289 TRP TRP A . n 
A 1 134 TRP 134 302 290 TRP TRP A . n 
A 1 135 PRO 135 303 291 PRO PRO A . n 
A 1 136 ILE 136 304 292 ILE ILE A . n 
A 1 137 VAL 137 305 293 VAL VAL A . n 
A 1 138 GLN 138 306 294 GLN GLN A . n 
A 1 139 GLY 139 307 295 GLY GLY A . n 
A 1 140 ARG 140 308 296 ARG ARG A . n 
A 1 141 ILE 141 309 297 ILE ILE A . n 
A 1 142 ASP 142 310 298 ASP ASP A . n 
A 1 143 ARG 143 311 299 ARG ARG A . n 
A 1 144 ALA 144 312 300 ALA ALA A . n 
A 1 145 LEU 145 313 301 LEU LEU A . n 
A 1 146 ALA 146 314 302 ALA ALA A . n 
A 1 147 ALA 147 315 303 ALA ALA A . n 
A 1 148 GLY 148 316 304 GLY GLY A . n 
A 1 149 PHE 149 317 305 PHE PHE A . n 
A 1 150 ASN 150 318 306 ASN ASN A . n 
A 1 151 GLY 151 319 307 GLY GLY A . n 
A 1 152 CYS 152 320 308 CYS CYS A . n 
A 1 153 TYR 153 321 309 TYR TYR A . n 
A 1 154 LEU 154 322 310 LEU LEU A . n 
A 1 155 ASP 155 323 311 ASP ASP A . n 
A 1 156 MET 156 324 312 MET MET A . n 
A 1 157 VAL 157 325 313 VAL VAL A . n 
A 1 158 VAL 158 326 314 VAL VAL A . n 
A 1 159 THR 159 327 315 THR THR A . n 
A 1 160 TYR 160 328 316 TYR TYR A . n 
A 1 161 GLU 161 329 317 GLU GLU A . n 
A 1 162 GLU 162 330 318 GLU GLU A . n 
A 1 163 ILE 163 331 319 ILE ILE A . n 
A 1 164 PRO 164 332 320 PRO PRO A . n 
A 1 165 ALA 165 333 321 ALA ALA A . n 
A 1 166 ASN 166 334 322 ASN ASN A . n 
A 1 167 SER 167 335 323 SER SER A . n 
A 1 168 ALA 168 336 324 ALA ALA A . n 
A 1 169 GLY 169 337 325 GLY GLY A . n 
A 1 170 THR 170 338 326 THR THR A . n 
A 1 171 ASN 171 339 327 ASN ASN A . n 
A 1 172 ARG 172 340 328 ARG ARG A . n 
A 1 173 ALA 173 341 329 ALA ALA A . n 
A 1 174 ASP 174 342 330 ASP ASP A . n 
A 1 175 LEU 175 343 331 LEU LEU A . n 
A 1 176 ALA 176 344 332 ALA ALA A . n 
A 1 177 ARG 177 345 333 ARG ARG A . n 
A 1 178 LYS 178 346 334 LYS LYS A . n 
A 1 179 MET 179 347 335 MET MET A . n 
A 1 180 VAL 180 348 336 VAL VAL A . n 
A 1 181 ALA 181 349 337 ALA ALA A . n 
A 1 182 LEU 182 350 338 LEU LEU A . n 
A 1 183 ILE 183 351 339 ILE ILE A . n 
A 1 184 ALA 184 352 340 ALA ALA A . n 
A 1 185 ARG 185 353 341 ARG ARG A . n 
A 1 186 ILE 186 354 342 ILE ILE A . n 
A 1 187 ASN 187 355 343 ASN ASN A . n 
A 1 188 THR 188 356 344 THR THR A . n 
A 1 189 TYR 189 357 345 TYR TYR A . n 
A 1 190 ALA 190 358 346 ALA ALA A . n 
A 1 191 LYS 191 359 347 LYS LYS A . n 
A 1 192 ALA 192 360 348 ALA ALA A . n 
A 1 193 ARG 193 361 349 ARG ARG A . n 
A 1 194 ASN 194 362 350 ASN ASN A . n 
A 1 195 PRO 195 363 351 PRO PRO A . n 
A 1 196 ASP 196 364 352 ASP ASP A . n 
A 1 197 PHE 197 365 353 PHE PHE A . n 
A 1 198 LYS 198 366 354 LYS LYS A . n 
A 1 199 VAL 199 367 355 VAL VAL A . n 
A 1 200 VAL 200 368 356 VAL VAL A . n 
A 1 201 PRO 201 369 357 PRO PRO A . n 
A 1 202 GLN 202 370 358 GLN GLN A . n 
A 1 203 ASN 203 371 359 ASN ASN A . n 
A 1 204 SER 204 372 360 SER SER A . n 
A 1 205 PRO 205 373 361 PRO PRO A . n 
A 1 206 GLU 206 374 362 GLU GLU A . n 
A 1 207 LEU 207 375 363 LEU LEU A . n 
A 1 208 VAL 208 376 364 VAL VAL A . n 
A 1 209 ASP 209 377 365 ASP ASP A . n 
A 1 210 ASP 210 378 366 ASP ASP A . n 
A 1 211 PRO 211 379 367 PRO PRO A . n 
A 1 212 ALA 212 380 368 ALA ALA A . n 
A 1 213 TYR 213 381 369 TYR TYR A . n 
A 1 214 LEU 214 382 370 LEU LEU A . n 
A 1 215 PRO 215 383 371 PRO PRO A . n 
A 1 216 ALA 216 384 372 ALA ALA A . n 
A 1 217 ILE 217 385 373 ILE ILE A . n 
A 1 218 ASP 218 386 374 ASP ASP A . n 
A 1 219 GLY 219 387 375 GLY GLY A . n 
A 1 220 LEU 220 388 376 LEU LEU A . n 
A 1 221 GLY 221 389 377 GLY GLY A . n 
A 1 222 MET 222 390 378 MET MET A . n 
A 1 223 GLU 223 391 379 GLU GLU A . n 
A 1 224 ASP 224 392 380 ASP ASP A . n 
A 1 225 MET 225 393 381 MET MET A . n 
A 1 226 TYR 226 394 382 TYR TYR A . n 
A 1 227 TRP 227 395 383 TRP TRP A . n 
A 1 228 SER 228 396 384 SER SER A . n 
A 1 229 ASP 229 397 385 ASP ASP A . n 
A 1 230 ASP 230 398 386 ASP ASP A . n 
A 1 231 VAL 231 399 387 VAL VAL A . n 
A 1 232 ALA 232 400 388 ALA ALA A . n 
A 1 233 CYS 233 401 389 CYS CYS A . n 
A 1 234 ASP 234 402 390 ASP ASP A . n 
A 1 235 GLU 235 403 391 GLU GLU A . n 
A 1 236 GLY 236 404 392 GLY GLY A . n 
A 1 237 TRP 237 405 393 TRP TRP A . n 
A 1 238 CYS 238 406 394 CYS CYS A . n 
A 1 239 GLU 239 407 395 GLU GLU A . n 
A 1 240 GLU 240 408 396 GLU GLU A . n 
A 1 241 ASN 241 409 397 ASN ASN A . n 
A 1 242 ARG 242 410 398 ARG ARG A . n 
A 1 243 THR 243 411 399 THR THR A . n 
A 1 244 ASN 244 412 400 ASN ASN A . n 
A 1 245 ALA 245 413 401 ALA ALA A . n 
A 1 246 ALA 246 414 402 ALA ALA A . n 
A 1 247 ARG 247 415 403 ARG ARG A . n 
A 1 248 VAL 248 416 404 VAL VAL A . n 
A 1 249 ARG 249 417 405 ARG ARG A . n 
A 1 250 ALA 250 418 406 ALA ALA A . n 
A 1 251 ALA 251 419 407 ALA ALA A . n 
A 1 252 GLY 252 420 408 GLY GLY A . n 
A 1 253 LYS 253 421 409 LYS LYS A . n 
A 1 254 LEU 254 422 410 LEU LEU A . n 
A 1 255 VAL 255 423 411 VAL VAL A . n 
A 1 256 LEU 256 424 412 LEU LEU A . n 
A 1 257 SER 257 425 413 SER SER A . n 
A 1 258 THR 258 426 414 THR THR A . n 
A 1 259 ASP 259 427 415 ASP ASP A . n 
A 1 260 TYR 260 428 416 TYR TYR A . n 
A 1 261 ALA 261 429 417 ALA ALA A . n 
A 1 262 THR 262 430 418 THR THR A . n 
A 1 263 GLN 263 431 419 GLN GLN A . n 
A 1 264 SER 264 432 420 SER SER A . n 
A 1 265 ALA 265 433 421 ALA ALA A . n 
A 1 266 HIS 266 434 422 HIS HIS A . n 
A 1 267 VAL 267 435 423 VAL VAL A . n 
A 1 268 ALA 268 436 424 ALA ALA A . n 
A 1 269 ASP 269 437 425 ASP ASP A . n 
A 1 270 ALA 270 438 426 ALA ALA A . n 
A 1 271 TYR 271 439 427 TYR TYR A . n 
A 1 272 THR 272 440 428 THR THR A . n 
A 1 273 ARG 273 441 429 ARG ARG A . n 
A 1 274 SER 274 442 430 SER SER A . n 
A 1 275 ARG 275 443 431 ARG ARG A . n 
A 1 276 ALA 276 444 432 ALA ALA A . n 
A 1 277 ALA 277 445 433 ALA ALA A . n 
A 1 278 GLY 278 446 434 GLY GLY A . n 
A 1 279 PHE 279 447 435 PHE PHE A . n 
A 1 280 VAL 280 448 436 VAL VAL A . n 
A 1 281 PRO 281 449 437 PRO PRO A . n 
A 1 282 TYR 282 450 438 TYR TYR A . n 
A 1 283 VAL 283 451 439 VAL VAL A . n 
A 1 284 THR 284 452 440 THR THR A . n 
A 1 285 VAL 285 453 441 VAL VAL A . n 
A 1 286 ARG 286 454 442 ARG ARG A . n 
A 1 287 ALA 287 455 443 ALA ALA A . n 
A 1 288 LEU 288 456 444 LEU LEU A . n 
A 1 289 ASP 289 457 445 ASP ASP A . n 
A 1 290 ARG 290 458 446 ARG ARG A . n 
A 1 291 VAL 291 459 447 VAL VAL A . n 
A 1 292 THR 292 460 448 THR THR A . n 
A 1 293 VAL 293 461 449 VAL VAL A . n 
A 1 294 ASN 294 462 450 ASN ASN A . n 
A 1 295 ALA 295 463 451 ALA ALA A . n 
A 1 296 GLY 296 464 452 GLY GLY A . n 
A 1 297 TRP 297 465 453 TRP TRP A . n 
A 1 298 ASP 298 466 454 ASP ASP A . n 
A 1 299 PRO 299 467 455 PRO PRO A . n 
A 1 300 GLN 300 468 456 GLN GLN A . n 
B 1 1   ASP 1   169 ?   ?   ?   D . n 
B 1 2   ALA 2   170 ?   ?   ?   D . n 
B 1 3   GLY 3   171 ?   ?   ?   D . n 
B 1 4   THR 4   172 ?   ?   ?   D . n 
B 1 5   PRO 5   173 ?   ?   ?   D . n 
B 1 6   THR 6   174 ?   ?   ?   D . n 
B 1 7   ASP 7   175 ?   ?   ?   D . n 
B 1 8   ALA 8   176 ?   ?   ?   D . n 
B 1 9   GLY 9   177 ?   ?   ?   D . n 
B 1 10  THR 10  178 ?   ?   ?   D . n 
B 1 11  PRO 11  179 ?   ?   ?   D . n 
B 1 12  THR 12  180 ?   ?   ?   D . n 
B 1 13  ASP 13  181 ?   ?   ?   D . n 
B 1 14  ALA 14  182 ?   ?   ?   D . n 
B 1 15  GLY 15  183 ?   ?   ?   D . n 
B 1 16  THR 16  184 ?   ?   ?   D . n 
B 1 17  PRO 17  185 ?   ?   ?   D . n 
B 1 18  THR 18  186 ?   ?   ?   D . n 
B 1 19  ASP 19  187 ?   ?   ?   D . n 
B 1 20  ALA 20  188 ?   ?   ?   D . n 
B 1 21  GLY 21  189 ?   ?   ?   D . n 
B 1 22  THR 22  190 ?   ?   ?   D . n 
B 1 23  PRO 23  191 ?   ?   ?   D . n 
B 1 24  THR 24  192 ?   ?   ?   D . n 
B 1 25  ASP 25  193 ?   ?   ?   D . n 
B 1 26  ALA 26  194 ?   ?   ?   D . n 
B 1 27  GLY 27  195 ?   ?   ?   D . n 
B 1 28  THR 28  196 ?   ?   ?   D . n 
B 1 29  GLN 29  197 185 GLN GLN D . n 
B 1 30  VAL 30  198 186 VAL VAL D . n 
B 1 31  PRO 31  199 187 PRO PRO D . n 
B 1 32  TRP 32  200 188 TRP TRP D . n 
B 1 33  SER 33  201 189 SER SER D . n 
B 1 34  ASN 34  202 190 ASN ASN D . n 
B 1 35  VAL 35  203 191 VAL VAL D . n 
B 1 36  LYS 36  204 192 LYS LYS D . n 
B 1 37  SER 37  205 193 SER SER D . n 
B 1 38  PHE 38  206 194 PHE PHE D . n 
B 1 39  THR 39  207 195 THR THR D . n 
B 1 40  TYR 40  208 196 TYR TYR D . n 
B 1 41  GLN 41  209 197 GLN GLN D . n 
B 1 42  LEU 42  210 198 LEU LEU D . n 
B 1 43  THR 43  211 199 THR THR D . n 
B 1 44  ASN 44  212 200 ASN ASN D . n 
B 1 45  TYR 45  213 201 TYR TYR D . n 
B 1 46  PRO 46  214 202 PRO PRO D . n 
B 1 47  GLN 47  215 203 GLN GLN D . n 
B 1 48  GLY 48  216 204 GLY GLY D . n 
B 1 49  LYS 49  217 205 LYS LYS D . n 
B 1 50  LEU 50  218 206 LEU LEU D . n 
B 1 51  ASP 51  219 207 ASP ASP D . n 
B 1 52  ALA 52  220 208 ALA ALA D . n 
B 1 53  ILE 53  221 209 ILE ILE D . n 
B 1 54  ALA 54  222 210 ALA ALA D . n 
B 1 55  ALA 55  223 211 ALA ALA D . n 
B 1 56  SER 56  224 212 SER SER D . n 
B 1 57  LYS 57  225 213 LYS LYS D . n 
B 1 58  PHE 58  226 214 PHE PHE D . n 
B 1 59  ASP 59  227 215 ASP ASP D . n 
B 1 60  LEU 60  228 216 LEU LEU D . n 
B 1 61  ALA 61  229 217 ALA ALA D . n 
B 1 62  ILE 62  230 218 ILE ILE D . n 
B 1 63  VAL 63  231 219 VAL VAL D . n 
B 1 64  GLU 64  232 220 GLU GLU D . n 
B 1 65  LEU 65  233 221 LEU LEU D . n 
B 1 66  VAL 66  234 222 VAL VAL D . n 
B 1 67  ARG 67  235 223 ARG ARG D . n 
B 1 68  ASP 68  236 224 ASP ASP D . n 
B 1 69  GLY 69  237 225 GLY GLY D . n 
B 1 70  SER 70  238 226 SER SER D . n 
B 1 71  SER 71  239 227 SER SER D . n 
B 1 72  GLY 72  240 228 GLY GLY D . n 
B 1 73  TYR 73  241 229 TYR TYR D . n 
B 1 74  PHE 74  242 230 PHE PHE D . n 
B 1 75  THR 75  243 231 THR THR D . n 
B 1 76  ALA 76  244 232 ALA ALA D . n 
B 1 77  ALA 77  245 233 ALA ALA D . n 
B 1 78  GLU 78  246 234 GLU GLU D . n 
B 1 79  ILE 79  247 235 ILE ILE D . n 
B 1 80  SER 80  248 236 SER SER D . n 
B 1 81  ALA 81  249 237 ALA ALA D . n 
B 1 82  LEU 82  250 238 LEU LEU D . n 
B 1 83  LYS 83  251 239 LYS LYS D . n 
B 1 84  ALA 84  252 240 ALA ALA D . n 
B 1 85  ARG 85  253 241 ARG ARG D . n 
B 1 86  GLY 86  254 242 GLY GLY D . n 
B 1 87  LYS 87  255 243 LYS LYS D . n 
B 1 88  GLN 88  256 244 GLN GLN D . n 
B 1 89  VAL 89  257 245 VAL VAL D . n 
B 1 90  LEU 90  258 246 LEU LEU D . n 
B 1 91  ALA 91  259 247 ALA ALA D . n 
B 1 92  TYR 92  260 248 TYR TYR D . n 
B 1 93  PHE 93  261 249 PHE PHE D . n 
B 1 94  GLU 94  262 250 GLU GLU D . n 
B 1 95  ILE 95  263 251 ILE ILE D . n 
B 1 96  GLY 96  264 252 GLY GLY D . n 
B 1 97  ALA 97  265 253 ALA ALA D . n 
B 1 98  ILE 98  266 254 ILE ILE D . n 
B 1 99  GLU 99  267 255 GLU GLU D . n 
B 1 100 GLU 100 268 256 GLU GLU D . n 
B 1 101 TYR 101 269 257 TYR TYR D . n 
B 1 102 ARG 102 270 258 ARG ARG D . n 
B 1 103 PRO 103 271 259 PRO PRO D . n 
B 1 104 GLU 104 272 260 GLU GLU D . n 
B 1 105 TRP 105 273 261 TRP TRP D . n 
B 1 106 SER 106 274 262 SER SER D . n 
B 1 107 GLN 107 275 263 GLN GLN D . n 
B 1 108 VAL 108 276 264 VAL VAL D . n 
B 1 109 PRO 109 277 265 PRO PRO D . n 
B 1 110 ALA 110 278 266 ALA ALA D . n 
B 1 111 ASP 111 279 267 ASP ASP D . n 
B 1 112 LEU 112 280 268 LEU LEU D . n 
B 1 113 LYS 113 281 269 LYS LYS D . n 
B 1 114 LEU 114 282 270 LEU LEU D . n 
B 1 115 GLY 115 283 271 GLY GLY D . n 
B 1 116 PRO 116 284 272 PRO PRO D . n 
B 1 117 VAL 117 285 273 VAL VAL D . n 
B 1 118 SER 118 286 274 SER SER D . n 
B 1 119 GLY 119 287 275 GLY GLY D . n 
B 1 120 TRP 120 288 276 TRP TRP D . n 
B 1 121 PRO 121 289 277 PRO PRO D . n 
B 1 122 ASP 122 290 278 ASP ASP D . n 
B 1 123 GLU 123 291 279 GLU GLU D . n 
B 1 124 GLN 124 292 280 GLN GLN D . n 
B 1 125 TYR 125 293 281 TYR TYR D . n 
B 1 126 VAL 126 294 282 VAL VAL D . n 
B 1 127 LYS 127 295 283 LYS LYS D . n 
B 1 128 TYR 128 296 284 TYR TYR D . n 
B 1 129 TRP 129 297 285 TRP TRP D . n 
B 1 130 ASP 130 298 286 ASP ASP D . n 
B 1 131 GLU 131 299 287 GLU GLU D . n 
B 1 132 ARG 132 300 288 ARG ARG D . n 
B 1 133 TRP 133 301 289 TRP TRP D . n 
B 1 134 TRP 134 302 290 TRP TRP D . n 
B 1 135 PRO 135 303 291 PRO PRO D . n 
B 1 136 ILE 136 304 292 ILE ILE D . n 
B 1 137 VAL 137 305 293 VAL VAL D . n 
B 1 138 GLN 138 306 294 GLN GLN D . n 
B 1 139 GLY 139 307 295 GLY GLY D . n 
B 1 140 ARG 140 308 296 ARG ARG D . n 
B 1 141 ILE 141 309 297 ILE ILE D . n 
B 1 142 ASP 142 310 298 ASP ASP D . n 
B 1 143 ARG 143 311 299 ARG ARG D . n 
B 1 144 ALA 144 312 300 ALA ALA D . n 
B 1 145 LEU 145 313 301 LEU LEU D . n 
B 1 146 ALA 146 314 302 ALA ALA D . n 
B 1 147 ALA 147 315 303 ALA ALA D . n 
B 1 148 GLY 148 316 304 GLY GLY D . n 
B 1 149 PHE 149 317 305 PHE PHE D . n 
B 1 150 ASN 150 318 306 ASN ASN D . n 
B 1 151 GLY 151 319 307 GLY GLY D . n 
B 1 152 CYS 152 320 308 CYS CYS D . n 
B 1 153 TYR 153 321 309 TYR TYR D . n 
B 1 154 LEU 154 322 310 LEU LEU D . n 
B 1 155 ASP 155 323 311 ASP ASP D . n 
B 1 156 MET 156 324 312 MET MET D . n 
B 1 157 VAL 157 325 313 VAL VAL D . n 
B 1 158 VAL 158 326 314 VAL VAL D . n 
B 1 159 THR 159 327 315 THR THR D . n 
B 1 160 TYR 160 328 316 TYR TYR D . n 
B 1 161 GLU 161 329 317 GLU GLU D . n 
B 1 162 GLU 162 330 318 GLU GLU D . n 
B 1 163 ILE 163 331 319 ILE ILE D . n 
B 1 164 PRO 164 332 320 PRO PRO D . n 
B 1 165 ALA 165 333 321 ALA ALA D . n 
B 1 166 ASN 166 334 322 ASN ASN D . n 
B 1 167 SER 167 335 323 SER SER D . n 
B 1 168 ALA 168 336 324 ALA ALA D . n 
B 1 169 GLY 169 337 325 GLY GLY D . n 
B 1 170 THR 170 338 326 THR THR D . n 
B 1 171 ASN 171 339 327 ASN ASN D . n 
B 1 172 ARG 172 340 328 ARG ARG D . n 
B 1 173 ALA 173 341 329 ALA ALA D . n 
B 1 174 ASP 174 342 330 ASP ASP D . n 
B 1 175 LEU 175 343 331 LEU LEU D . n 
B 1 176 ALA 176 344 332 ALA ALA D . n 
B 1 177 ARG 177 345 333 ARG ARG D . n 
B 1 178 LYS 178 346 334 LYS LYS D . n 
B 1 179 MET 179 347 335 MET MET D . n 
B 1 180 VAL 180 348 336 VAL VAL D . n 
B 1 181 ALA 181 349 337 ALA ALA D . n 
B 1 182 LEU 182 350 338 LEU LEU D . n 
B 1 183 ILE 183 351 339 ILE ILE D . n 
B 1 184 ALA 184 352 340 ALA ALA D . n 
B 1 185 ARG 185 353 341 ARG ARG D . n 
B 1 186 ILE 186 354 342 ILE ILE D . n 
B 1 187 ASN 187 355 343 ASN ASN D . n 
B 1 188 THR 188 356 344 THR THR D . n 
B 1 189 TYR 189 357 345 TYR TYR D . n 
B 1 190 ALA 190 358 346 ALA ALA D . n 
B 1 191 LYS 191 359 347 LYS LYS D . n 
B 1 192 ALA 192 360 348 ALA ALA D . n 
B 1 193 ARG 193 361 349 ARG ARG D . n 
B 1 194 ASN 194 362 350 ASN ASN D . n 
B 1 195 PRO 195 363 351 PRO PRO D . n 
B 1 196 ASP 196 364 352 ASP ASP D . n 
B 1 197 PHE 197 365 353 PHE PHE D . n 
B 1 198 LYS 198 366 354 LYS LYS D . n 
B 1 199 VAL 199 367 355 VAL VAL D . n 
B 1 200 VAL 200 368 356 VAL VAL D . n 
B 1 201 PRO 201 369 357 PRO PRO D . n 
B 1 202 GLN 202 370 358 GLN GLN D . n 
B 1 203 ASN 203 371 359 ASN ASN D . n 
B 1 204 SER 204 372 360 SER SER D . n 
B 1 205 PRO 205 373 361 PRO PRO D . n 
B 1 206 GLU 206 374 362 GLU GLU D . n 
B 1 207 LEU 207 375 363 LEU LEU D . n 
B 1 208 VAL 208 376 364 VAL VAL D . n 
B 1 209 ASP 209 377 365 ASP ASP D . n 
B 1 210 ASP 210 378 366 ASP ASP D . n 
B 1 211 PRO 211 379 367 PRO PRO D . n 
B 1 212 ALA 212 380 368 ALA ALA D . n 
B 1 213 TYR 213 381 369 TYR TYR D . n 
B 1 214 LEU 214 382 370 LEU LEU D . n 
B 1 215 PRO 215 383 371 PRO PRO D . n 
B 1 216 ALA 216 384 372 ALA ALA D . n 
B 1 217 ILE 217 385 373 ILE ILE D . n 
B 1 218 ASP 218 386 374 ASP ASP D . n 
B 1 219 GLY 219 387 375 GLY GLY D . n 
B 1 220 LEU 220 388 376 LEU LEU D . n 
B 1 221 GLY 221 389 377 GLY GLY D . n 
B 1 222 MET 222 390 378 MET MET D . n 
B 1 223 GLU 223 391 379 GLU GLU D . n 
B 1 224 ASP 224 392 380 ASP ASP D . n 
B 1 225 MET 225 393 381 MET MET D . n 
B 1 226 TYR 226 394 382 TYR TYR D . n 
B 1 227 TRP 227 395 383 TRP TRP D . n 
B 1 228 SER 228 396 384 SER SER D . n 
B 1 229 ASP 229 397 385 ASP ASP D . n 
B 1 230 ASP 230 398 386 ASP ASP D . n 
B 1 231 VAL 231 399 387 VAL VAL D . n 
B 1 232 ALA 232 400 388 ALA ALA D . n 
B 1 233 CYS 233 401 389 CYS CYS D . n 
B 1 234 ASP 234 402 390 ASP ASP D . n 
B 1 235 GLU 235 403 391 GLU GLU D . n 
B 1 236 GLY 236 404 392 GLY GLY D . n 
B 1 237 TRP 237 405 393 TRP TRP D . n 
B 1 238 CYS 238 406 394 CYS CYS D . n 
B 1 239 GLU 239 407 395 GLU GLU D . n 
B 1 240 GLU 240 408 396 GLU GLU D . n 
B 1 241 ASN 241 409 397 ASN ASN D . n 
B 1 242 ARG 242 410 398 ARG ARG D . n 
B 1 243 THR 243 411 399 THR THR D . n 
B 1 244 ASN 244 412 400 ASN ASN D . n 
B 1 245 ALA 245 413 401 ALA ALA D . n 
B 1 246 ALA 246 414 402 ALA ALA D . n 
B 1 247 ARG 247 415 403 ARG ARG D . n 
B 1 248 VAL 248 416 404 VAL VAL D . n 
B 1 249 ARG 249 417 405 ARG ARG D . n 
B 1 250 ALA 250 418 406 ALA ALA D . n 
B 1 251 ALA 251 419 407 ALA ALA D . n 
B 1 252 GLY 252 420 408 GLY GLY D . n 
B 1 253 LYS 253 421 409 LYS LYS D . n 
B 1 254 LEU 254 422 410 LEU LEU D . n 
B 1 255 VAL 255 423 411 VAL VAL D . n 
B 1 256 LEU 256 424 412 LEU LEU D . n 
B 1 257 SER 257 425 413 SER SER D . n 
B 1 258 THR 258 426 414 THR THR D . n 
B 1 259 ASP 259 427 415 ASP ASP D . n 
B 1 260 TYR 260 428 416 TYR TYR D . n 
B 1 261 ALA 261 429 417 ALA ALA D . n 
B 1 262 THR 262 430 418 THR THR D . n 
B 1 263 GLN 263 431 419 GLN GLN D . n 
B 1 264 SER 264 432 420 SER SER D . n 
B 1 265 ALA 265 433 421 ALA ALA D . n 
B 1 266 HIS 266 434 422 HIS HIS D . n 
B 1 267 VAL 267 435 423 VAL VAL D . n 
B 1 268 ALA 268 436 424 ALA ALA D . n 
B 1 269 ASP 269 437 425 ASP ASP D . n 
B 1 270 ALA 270 438 426 ALA ALA D . n 
B 1 271 TYR 271 439 427 TYR TYR D . n 
B 1 272 THR 272 440 428 THR THR D . n 
B 1 273 ARG 273 441 429 ARG ARG D . n 
B 1 274 SER 274 442 430 SER SER D . n 
B 1 275 ARG 275 443 431 ARG ARG D . n 
B 1 276 ALA 276 444 432 ALA ALA D . n 
B 1 277 ALA 277 445 433 ALA ALA D . n 
B 1 278 GLY 278 446 434 GLY GLY D . n 
B 1 279 PHE 279 447 435 PHE PHE D . n 
B 1 280 VAL 280 448 436 VAL VAL D . n 
B 1 281 PRO 281 449 437 PRO PRO D . n 
B 1 282 TYR 282 450 438 TYR TYR D . n 
B 1 283 VAL 283 451 439 VAL VAL D . n 
B 1 284 THR 284 452 440 THR THR D . n 
B 1 285 VAL 285 453 441 VAL VAL D . n 
B 1 286 ARG 286 454 442 ARG ARG D . n 
B 1 287 ALA 287 455 443 ALA ALA D . n 
B 1 288 LEU 288 456 444 LEU LEU D . n 
B 1 289 ASP 289 457 445 ASP ASP D . n 
B 1 290 ARG 290 458 446 ARG ARG D . n 
B 1 291 VAL 291 459 447 VAL VAL D . n 
B 1 292 THR 292 460 448 THR THR D . n 
B 1 293 VAL 293 461 449 VAL VAL D . n 
B 1 294 ASN 294 462 450 ASN ASN D . n 
B 1 295 ALA 295 463 451 ALA ALA D . n 
B 1 296 GLY 296 464 452 GLY GLY D . n 
B 1 297 TRP 297 465 453 TRP TRP D . n 
B 1 298 ASP 298 466 454 ASP ASP D . n 
B 1 299 PRO 299 467 455 PRO PRO D . n 
B 1 300 GLN 300 468 456 GLN GLN D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SO4 1   501 501 SO4 SO4 A . 
D 2 SO4 1   501 501 SO4 SO4 D . 
E 3 HOH 1   601 839 HOH HOH A . 
E 3 HOH 2   602 869 HOH HOH A . 
E 3 HOH 3   603 814 HOH HOH A . 
E 3 HOH 4   604 769 HOH HOH A . 
E 3 HOH 5   605 970 HOH HOH A . 
E 3 HOH 6   606 719 HOH HOH A . 
E 3 HOH 7   607 694 HOH HOH A . 
E 3 HOH 8   608 636 HOH HOH A . 
E 3 HOH 9   609 747 HOH HOH A . 
E 3 HOH 10  610 726 HOH HOH A . 
E 3 HOH 11  611 894 HOH HOH A . 
E 3 HOH 12  612 897 HOH HOH A . 
E 3 HOH 13  613 752 HOH HOH A . 
E 3 HOH 14  614 678 HOH HOH A . 
E 3 HOH 15  615 766 HOH HOH A . 
E 3 HOH 16  616 672 HOH HOH A . 
E 3 HOH 17  617 634 HOH HOH A . 
E 3 HOH 18  618 693 HOH HOH A . 
E 3 HOH 19  619 746 HOH HOH A . 
E 3 HOH 20  620 905 HOH HOH A . 
E 3 HOH 21  621 876 HOH HOH A . 
E 3 HOH 22  622 960 HOH HOH A . 
E 3 HOH 23  623 874 HOH HOH A . 
E 3 HOH 24  624 685 HOH HOH A . 
E 3 HOH 25  625 720 HOH HOH A . 
E 3 HOH 26  626 880 HOH HOH A . 
E 3 HOH 27  627 819 HOH HOH A . 
E 3 HOH 28  628 659 HOH HOH A . 
E 3 HOH 29  629 731 HOH HOH A . 
E 3 HOH 30  630 642 HOH HOH A . 
E 3 HOH 31  631 926 HOH HOH A . 
E 3 HOH 32  632 837 HOH HOH A . 
E 3 HOH 33  633 687 HOH HOH A . 
E 3 HOH 34  634 637 HOH HOH A . 
E 3 HOH 35  635 912 HOH HOH A . 
E 3 HOH 36  636 717 HOH HOH A . 
E 3 HOH 37  637 893 HOH HOH A . 
E 3 HOH 38  638 918 HOH HOH A . 
E 3 HOH 39  639 688 HOH HOH A . 
E 3 HOH 40  640 756 HOH HOH A . 
E 3 HOH 41  641 994 HOH HOH A . 
E 3 HOH 42  642 809 HOH HOH A . 
E 3 HOH 43  643 606 HOH HOH A . 
E 3 HOH 44  644 624 HOH HOH A . 
E 3 HOH 45  645 986 HOH HOH A . 
E 3 HOH 46  646 889 HOH HOH A . 
E 3 HOH 47  647 915 HOH HOH A . 
E 3 HOH 48  648 671 HOH HOH A . 
E 3 HOH 49  649 611 HOH HOH A . 
E 3 HOH 50  650 721 HOH HOH A . 
E 3 HOH 51  651 788 HOH HOH A . 
E 3 HOH 52  652 669 HOH HOH A . 
E 3 HOH 53  653 666 HOH HOH A . 
E 3 HOH 54  654 898 HOH HOH A . 
E 3 HOH 55  655 602 HOH HOH A . 
E 3 HOH 56  656 826 HOH HOH A . 
E 3 HOH 57  657 710 HOH HOH A . 
E 3 HOH 58  658 925 HOH HOH A . 
E 3 HOH 59  659 651 HOH HOH A . 
E 3 HOH 60  660 827 HOH HOH A . 
E 3 HOH 61  661 663 HOH HOH A . 
E 3 HOH 62  662 757 HOH HOH A . 
E 3 HOH 63  663 945 HOH HOH A . 
E 3 HOH 64  664 682 HOH HOH A . 
E 3 HOH 65  665 616 HOH HOH A . 
E 3 HOH 66  666 696 HOH HOH A . 
E 3 HOH 67  667 765 HOH HOH A . 
E 3 HOH 68  668 828 HOH HOH A . 
E 3 HOH 69  669 791 HOH HOH A . 
E 3 HOH 70  670 653 HOH HOH A . 
E 3 HOH 71  671 798 HOH HOH A . 
E 3 HOH 72  672 740 HOH HOH A . 
E 3 HOH 73  673 776 HOH HOH A . 
E 3 HOH 74  674 750 HOH HOH A . 
E 3 HOH 75  675 900 HOH HOH A . 
E 3 HOH 76  676 797 HOH HOH A . 
E 3 HOH 77  677 674 HOH HOH A . 
E 3 HOH 78  678 784 HOH HOH A . 
E 3 HOH 79  679 706 HOH HOH A . 
E 3 HOH 80  680 709 HOH HOH A . 
E 3 HOH 81  681 640 HOH HOH A . 
E 3 HOH 82  682 743 HOH HOH A . 
E 3 HOH 83  683 754 HOH HOH A . 
E 3 HOH 84  684 830 HOH HOH A . 
E 3 HOH 85  685 695 HOH HOH A . 
E 3 HOH 86  686 613 HOH HOH A . 
E 3 HOH 87  687 751 HOH HOH A . 
E 3 HOH 88  688 620 HOH HOH A . 
E 3 HOH 89  689 817 HOH HOH A . 
E 3 HOH 90  690 648 HOH HOH A . 
E 3 HOH 91  691 625 HOH HOH A . 
E 3 HOH 92  692 755 HOH HOH A . 
E 3 HOH 93  693 660 HOH HOH A . 
E 3 HOH 94  694 603 HOH HOH A . 
E 3 HOH 95  695 626 HOH HOH A . 
E 3 HOH 96  696 641 HOH HOH A . 
E 3 HOH 97  697 919 HOH HOH A . 
E 3 HOH 98  698 947 HOH HOH A . 
E 3 HOH 99  699 670 HOH HOH A . 
E 3 HOH 100 700 891 HOH HOH A . 
E 3 HOH 101 701 683 HOH HOH A . 
E 3 HOH 102 702 741 HOH HOH A . 
E 3 HOH 103 703 738 HOH HOH A . 
E 3 HOH 104 704 811 HOH HOH A . 
E 3 HOH 105 705 650 HOH HOH A . 
E 3 HOH 106 706 911 HOH HOH A . 
E 3 HOH 107 707 938 HOH HOH A . 
E 3 HOH 108 708 675 HOH HOH A . 
E 3 HOH 109 709 628 HOH HOH A . 
E 3 HOH 110 710 877 HOH HOH A . 
E 3 HOH 111 711 676 HOH HOH A . 
E 3 HOH 112 712 722 HOH HOH A . 
E 3 HOH 113 713 767 HOH HOH A . 
E 3 HOH 114 714 922 HOH HOH A . 
E 3 HOH 115 715 698 HOH HOH A . 
E 3 HOH 116 716 605 HOH HOH A . 
E 3 HOH 117 717 681 HOH HOH A . 
E 3 HOH 118 718 727 HOH HOH A . 
E 3 HOH 119 719 621 HOH HOH A . 
E 3 HOH 120 720 989 HOH HOH A . 
E 3 HOH 121 721 768 HOH HOH A . 
E 3 HOH 122 722 643 HOH HOH A . 
E 3 HOH 123 723 609 HOH HOH A . 
E 3 HOH 124 724 974 HOH HOH A . 
E 3 HOH 125 725 604 HOH HOH A . 
E 3 HOH 126 726 633 HOH HOH A . 
E 3 HOH 127 727 629 HOH HOH A . 
E 3 HOH 128 728 644 HOH HOH A . 
E 3 HOH 129 729 729 HOH HOH A . 
E 3 HOH 130 730 873 HOH HOH A . 
E 3 HOH 131 731 990 HOH HOH A . 
E 3 HOH 132 732 607 HOH HOH A . 
E 3 HOH 133 733 652 HOH HOH A . 
E 3 HOH 134 734 883 HOH HOH A . 
E 3 HOH 135 735 795 HOH HOH A . 
E 3 HOH 136 736 692 HOH HOH A . 
E 3 HOH 137 737 783 HOH HOH A . 
E 3 HOH 138 738 984 HOH HOH A . 
E 3 HOH 139 739 921 HOH HOH A . 
E 3 HOH 140 740 686 HOH HOH A . 
E 3 HOH 141 741 835 HOH HOH A . 
E 3 HOH 142 742 619 HOH HOH A . 
E 3 HOH 143 743 823 HOH HOH A . 
E 3 HOH 144 744 988 HOH HOH A . 
E 3 HOH 145 745 748 HOH HOH A . 
E 3 HOH 146 746 638 HOH HOH A . 
E 3 HOH 147 747 689 HOH HOH A . 
E 3 HOH 148 748 800 HOH HOH A . 
E 3 HOH 149 749 829 HOH HOH A . 
E 3 HOH 150 750 736 HOH HOH A . 
E 3 HOH 151 751 608 HOH HOH A . 
E 3 HOH 152 752 728 HOH HOH A . 
E 3 HOH 153 753 612 HOH HOH A . 
E 3 HOH 154 754 635 HOH HOH A . 
E 3 HOH 155 755 684 HOH HOH A . 
E 3 HOH 156 756 617 HOH HOH A . 
E 3 HOH 157 757 713 HOH HOH A . 
E 3 HOH 158 758 715 HOH HOH A . 
E 3 HOH 159 759 703 HOH HOH A . 
E 3 HOH 160 760 762 HOH HOH A . 
E 3 HOH 161 761 639 HOH HOH A . 
E 3 HOH 162 762 631 HOH HOH A . 
E 3 HOH 163 763 661 HOH HOH A . 
E 3 HOH 164 764 667 HOH HOH A . 
E 3 HOH 165 765 749 HOH HOH A . 
E 3 HOH 166 766 771 HOH HOH A . 
E 3 HOH 167 767 690 HOH HOH A . 
E 3 HOH 168 768 627 HOH HOH A . 
E 3 HOH 169 769 764 HOH HOH A . 
E 3 HOH 170 770 796 HOH HOH A . 
E 3 HOH 171 771 680 HOH HOH A . 
E 3 HOH 172 772 649 HOH HOH A . 
E 3 HOH 173 773 936 HOH HOH A . 
E 3 HOH 174 774 890 HOH HOH A . 
E 3 HOH 175 775 759 HOH HOH A . 
E 3 HOH 176 776 630 HOH HOH A . 
E 3 HOH 177 777 820 HOH HOH A . 
E 3 HOH 178 778 618 HOH HOH A . 
E 3 HOH 179 779 704 HOH HOH A . 
E 3 HOH 180 780 705 HOH HOH A . 
E 3 HOH 181 781 782 HOH HOH A . 
E 3 HOH 182 782 632 HOH HOH A . 
E 3 HOH 183 783 677 HOH HOH A . 
E 3 HOH 184 784 799 HOH HOH A . 
E 3 HOH 185 785 697 HOH HOH A . 
E 3 HOH 186 786 892 HOH HOH A . 
E 3 HOH 187 787 774 HOH HOH A . 
E 3 HOH 188 788 610 HOH HOH A . 
E 3 HOH 189 789 985 HOH HOH A . 
E 3 HOH 190 790 818 HOH HOH A . 
E 3 HOH 191 791 815 HOH HOH A . 
E 3 HOH 192 792 763 HOH HOH A . 
E 3 HOH 193 793 732 HOH HOH A . 
E 3 HOH 194 794 735 HOH HOH A . 
E 3 HOH 195 795 601 HOH HOH A . 
E 3 HOH 196 796 987 HOH HOH A . 
E 3 HOH 197 797 901 HOH HOH A . 
E 3 HOH 198 798 927 HOH HOH A . 
E 3 HOH 199 799 758 HOH HOH A . 
E 3 HOH 200 800 793 HOH HOH A . 
E 3 HOH 201 801 655 HOH HOH A . 
E 3 HOH 202 802 646 HOH HOH A . 
E 3 HOH 203 803 615 HOH HOH A . 
E 3 HOH 204 804 786 HOH HOH A . 
E 3 HOH 205 805 733 HOH HOH A . 
E 3 HOH 206 806 614 HOH HOH A . 
E 3 HOH 207 807 917 HOH HOH A . 
E 3 HOH 208 808 895 HOH HOH A . 
E 3 HOH 209 809 664 HOH HOH A . 
E 3 HOH 210 810 832 HOH HOH A . 
E 3 HOH 211 811 665 HOH HOH A . 
E 3 HOH 212 812 833 HOH HOH A . 
E 3 HOH 213 813 930 HOH HOH A . 
E 3 HOH 214 814 668 HOH HOH A . 
E 3 HOH 215 815 739 HOH HOH A . 
E 3 HOH 216 816 975 HOH HOH A . 
E 3 HOH 217 817 903 HOH HOH A . 
E 3 HOH 218 818 977 HOH HOH A . 
E 3 HOH 219 819 914 HOH HOH A . 
E 3 HOH 220 820 654 HOH HOH A . 
E 3 HOH 221 821 920 HOH HOH A . 
E 3 HOH 222 822 953 HOH HOH A . 
E 3 HOH 223 823 931 HOH HOH A . 
E 3 HOH 224 824 949 HOH HOH A . 
E 3 HOH 225 825 896 HOH HOH A . 
E 3 HOH 226 826 941 HOH HOH A . 
E 3 HOH 227 827 760 HOH HOH A . 
E 3 HOH 228 828 775 HOH HOH A . 
E 3 HOH 229 829 882 HOH HOH A . 
E 3 HOH 230 830 779 HOH HOH A . 
E 3 HOH 231 831 707 HOH HOH A . 
E 3 HOH 232 832 662 HOH HOH A . 
E 3 HOH 233 833 657 HOH HOH A . 
E 3 HOH 234 834 924 HOH HOH A . 
E 3 HOH 235 835 702 HOH HOH A . 
E 3 HOH 236 836 967 HOH HOH A . 
E 3 HOH 237 837 840 HOH HOH A . 
E 3 HOH 238 838 868 HOH HOH A . 
E 3 HOH 239 839 934 HOH HOH A . 
E 3 HOH 240 840 656 HOH HOH A . 
E 3 HOH 241 841 708 HOH HOH A . 
E 3 HOH 242 842 714 HOH HOH A . 
E 3 HOH 243 843 904 HOH HOH A . 
E 3 HOH 244 844 790 HOH HOH A . 
E 3 HOH 245 845 842 HOH HOH A . 
E 3 HOH 246 846 852 HOH HOH A . 
E 3 HOH 247 847 622 HOH HOH A . 
E 3 HOH 248 848 942 HOH HOH A . 
E 3 HOH 249 849 679 HOH HOH A . 
E 3 HOH 250 850 850 HOH HOH A . 
E 3 HOH 251 851 993 HOH HOH A . 
E 3 HOH 252 852 870 HOH HOH A . 
E 3 HOH 253 853 862 HOH HOH A . 
E 3 HOH 254 854 864 HOH HOH A . 
E 3 HOH 255 855 961 HOH HOH A . 
E 3 HOH 256 856 699 HOH HOH A . 
E 3 HOH 257 857 963 HOH HOH A . 
E 3 HOH 258 858 899 HOH HOH A . 
E 3 HOH 259 859 976 HOH HOH A . 
E 3 HOH 260 860 857 HOH HOH A . 
E 3 HOH 261 861 913 HOH HOH A . 
E 3 HOH 262 862 810 HOH HOH A . 
E 3 HOH 263 863 939 HOH HOH A . 
E 3 HOH 264 864 916 HOH HOH A . 
E 3 HOH 265 865 923 HOH HOH A . 
E 3 HOH 266 866 932 HOH HOH A . 
E 3 HOH 267 867 955 HOH HOH A . 
E 3 HOH 268 868 973 HOH HOH A . 
E 3 HOH 269 869 781 HOH HOH A . 
E 3 HOH 270 870 979 HOH HOH A . 
E 3 HOH 271 871 808 HOH HOH A . 
E 3 HOH 272 872 865 HOH HOH A . 
E 3 HOH 273 873 723 HOH HOH A . 
E 3 HOH 274 874 878 HOH HOH A . 
E 3 HOH 275 875 957 HOH HOH A . 
E 3 HOH 276 876 708 HOH HOH A . 
E 3 HOH 277 877 718 HOH HOH A . 
E 3 HOH 278 878 853 HOH HOH A . 
E 3 HOH 279 879 983 HOH HOH A . 
E 3 HOH 280 880 940 HOH HOH A . 
E 3 HOH 281 881 928 HOH HOH A . 
E 3 HOH 282 882 770 HOH HOH A . 
E 3 HOH 283 883 956 HOH HOH A . 
E 3 HOH 284 884 929 HOH HOH A . 
E 3 HOH 285 885 843 HOH HOH A . 
E 3 HOH 286 886 964 HOH HOH A . 
E 3 HOH 287 887 954 HOH HOH A . 
E 3 HOH 288 888 848 HOH HOH A . 
E 3 HOH 289 889 806 HOH HOH A . 
E 3 HOH 290 890 943 HOH HOH A . 
E 3 HOH 291 891 645 HOH HOH A . 
E 3 HOH 292 892 966 HOH HOH A . 
E 3 HOH 293 893 807 HOH HOH A . 
E 3 HOH 294 894 854 HOH HOH A . 
E 3 HOH 295 895 948 HOH HOH A . 
E 3 HOH 296 896 996 HOH HOH A . 
E 3 HOH 297 897 737 HOH HOH A . 
E 3 HOH 298 898 777 HOH HOH A . 
E 3 HOH 299 899 965 HOH HOH A . 
E 3 HOH 300 900 935 HOH HOH A . 
E 3 HOH 301 901 946 HOH HOH A . 
E 3 HOH 302 902 861 HOH HOH A . 
E 3 HOH 303 903 851 HOH HOH A . 
E 3 HOH 304 904 849 HOH HOH A . 
E 3 HOH 305 905 711 HOH HOH A . 
E 3 HOH 306 906 855 HOH HOH A . 
E 3 HOH 307 907 858 HOH HOH A . 
E 3 HOH 308 908 787 HOH HOH A . 
E 3 HOH 309 909 821 HOH HOH A . 
E 3 HOH 310 910 962 HOH HOH A . 
E 3 HOH 311 911 647 HOH HOH A . 
E 3 HOH 312 912 937 HOH HOH A . 
E 3 HOH 313 913 691 HOH HOH A . 
E 3 HOH 314 914 712 HOH HOH A . 
E 3 HOH 315 915 906 HOH HOH A . 
E 3 HOH 316 916 673 HOH HOH A . 
E 3 HOH 317 917 658 HOH HOH A . 
E 3 HOH 318 918 856 HOH HOH A . 
E 3 HOH 319 919 787 HOH HOH A . 
E 3 HOH 320 920 959 HOH HOH A . 
E 3 HOH 321 921 801 HOH HOH A . 
E 3 HOH 322 922 753 HOH HOH A . 
E 3 HOH 323 923 952 HOH HOH A . 
E 3 HOH 324 924 860 HOH HOH A . 
E 3 HOH 325 925 812 HOH HOH A . 
E 3 HOH 326 926 806 HOH HOH A . 
E 3 HOH 327 927 730 HOH HOH A . 
E 3 HOH 328 928 997 HOH HOH A . 
E 3 HOH 329 929 944 HOH HOH A . 
E 3 HOH 330 930 950 HOH HOH A . 
E 3 HOH 331 931 716 HOH HOH A . 
E 3 HOH 332 932 881 HOH HOH A . 
E 3 HOH 333 933 951 HOH HOH A . 
E 3 HOH 334 934 745 HOH HOH A . 
E 3 HOH 335 935 958 HOH HOH A . 
E 3 HOH 336 936 980 HOH HOH A . 
E 3 HOH 337 937 978 HOH HOH A . 
E 3 HOH 338 938 846 HOH HOH A . 
F 3 HOH 1   601 706 HOH HOH D . 
F 3 HOH 2   602 607 HOH HOH D . 
F 3 HOH 3   603 679 HOH HOH D . 
F 3 HOH 4   604 656 HOH HOH D . 
F 3 HOH 5   605 624 HOH HOH D . 
F 3 HOH 6   606 635 HOH HOH D . 
F 3 HOH 7   607 686 HOH HOH D . 
F 3 HOH 8   608 602 HOH HOH D . 
F 3 HOH 9   609 640 HOH HOH D . 
F 3 HOH 10  610 777 HOH HOH D . 
F 3 HOH 11  611 732 HOH HOH D . 
F 3 HOH 12  612 649 HOH HOH D . 
F 3 HOH 13  613 982 HOH HOH D . 
F 3 HOH 14  614 995 HOH HOH D . 
F 3 HOH 15  615 869 HOH HOH D . 
F 3 HOH 16  616 722 HOH HOH D . 
F 3 HOH 17  617 660 HOH HOH D . 
F 3 HOH 18  618 813 HOH HOH D . 
F 3 HOH 19  619 969 HOH HOH D . 
F 3 HOH 20  620 616 HOH HOH D . 
F 3 HOH 21  621 814 HOH HOH D . 
F 3 HOH 22  622 820 HOH HOH D . 
F 3 HOH 23  623 724 HOH HOH D . 
F 3 HOH 24  624 641 HOH HOH D . 
F 3 HOH 25  625 887 HOH HOH D . 
F 3 HOH 26  626 671 HOH HOH D . 
F 3 HOH 27  627 636 HOH HOH D . 
F 3 HOH 28  628 663 HOH HOH D . 
F 3 HOH 29  629 644 HOH HOH D . 
F 3 HOH 30  630 767 HOH HOH D . 
F 3 HOH 31  631 839 HOH HOH D . 
F 3 HOH 32  632 639 HOH HOH D . 
F 3 HOH 33  633 885 HOH HOH D . 
F 3 HOH 34  634 991 HOH HOH D . 
F 3 HOH 35  635 603 HOH HOH D . 
F 3 HOH 36  636 971 HOH HOH D . 
F 3 HOH 37  637 871 HOH HOH D . 
F 3 HOH 38  638 728 HOH HOH D . 
F 3 HOH 39  639 884 HOH HOH D . 
F 3 HOH 40  640 678 HOH HOH D . 
F 3 HOH 41  641 621 HOH HOH D . 
F 3 HOH 42  642 666 HOH HOH D . 
F 3 HOH 43  643 710 HOH HOH D . 
F 3 HOH 44  644 747 HOH HOH D . 
F 3 HOH 45  645 727 HOH HOH D . 
F 3 HOH 46  646 698 HOH HOH D . 
F 3 HOH 47  647 612 HOH HOH D . 
F 3 HOH 48  648 739 HOH HOH D . 
F 3 HOH 49  649 682 HOH HOH D . 
F 3 HOH 50  650 817 HOH HOH D . 
F 3 HOH 51  651 750 HOH HOH D . 
F 3 HOH 52  652 681 HOH HOH D . 
F 3 HOH 53  653 674 HOH HOH D . 
F 3 HOH 54  654 786 HOH HOH D . 
F 3 HOH 55  655 637 HOH HOH D . 
F 3 HOH 56  656 620 HOH HOH D . 
F 3 HOH 57  657 972 HOH HOH D . 
F 3 HOH 58  658 754 HOH HOH D . 
F 3 HOH 59  659 888 HOH HOH D . 
F 3 HOH 60  660 605 HOH HOH D . 
F 3 HOH 61  661 634 HOH HOH D . 
F 3 HOH 62  662 643 HOH HOH D . 
F 3 HOH 63  663 631 HOH HOH D . 
F 3 HOH 64  664 633 HOH HOH D . 
F 3 HOH 65  665 828 HOH HOH D . 
F 3 HOH 66  666 688 HOH HOH D . 
F 3 HOH 67  667 768 HOH HOH D . 
F 3 HOH 68  668 696 HOH HOH D . 
F 3 HOH 69  669 653 HOH HOH D . 
F 3 HOH 70  670 659 HOH HOH D . 
F 3 HOH 71  671 629 HOH HOH D . 
F 3 HOH 72  672 619 HOH HOH D . 
F 3 HOH 73  673 769 HOH HOH D . 
F 3 HOH 74  674 661 HOH HOH D . 
F 3 HOH 75  675 684 HOH HOH D . 
F 3 HOH 76  676 685 HOH HOH D . 
F 3 HOH 77  677 609 HOH HOH D . 
F 3 HOH 78  678 628 HOH HOH D . 
F 3 HOH 79  679 700 HOH HOH D . 
F 3 HOH 80  680 625 HOH HOH D . 
F 3 HOH 81  681 707 HOH HOH D . 
F 3 HOH 82  682 670 HOH HOH D . 
F 3 HOH 83  683 766 HOH HOH D . 
F 3 HOH 84  684 779 HOH HOH D . 
F 3 HOH 85  685 968 HOH HOH D . 
F 3 HOH 86  686 724 HOH HOH D . 
F 3 HOH 87  687 604 HOH HOH D . 
F 3 HOH 88  688 733 HOH HOH D . 
F 3 HOH 89  689 618 HOH HOH D . 
F 3 HOH 90  690 709 HOH HOH D . 
F 3 HOH 91  691 677 HOH HOH D . 
F 3 HOH 92  692 646 HOH HOH D . 
F 3 HOH 93  693 615 HOH HOH D . 
F 3 HOH 94  694 713 HOH HOH D . 
F 3 HOH 95  695 626 HOH HOH D . 
F 3 HOH 96  696 655 HOH HOH D . 
F 3 HOH 97  697 689 HOH HOH D . 
F 3 HOH 98  698 695 HOH HOH D . 
F 3 HOH 99  699 627 HOH HOH D . 
F 3 HOH 100 700 858 HOH HOH D . 
F 3 HOH 101 701 652 HOH HOH D . 
F 3 HOH 102 702 782 HOH HOH D . 
F 3 HOH 103 703 741 HOH HOH D . 
F 3 HOH 104 704 804 HOH HOH D . 
F 3 HOH 105 705 680 HOH HOH D . 
F 3 HOH 106 706 895 HOH HOH D . 
F 3 HOH 107 707 882 HOH HOH D . 
F 3 HOH 108 708 632 HOH HOH D . 
F 3 HOH 109 709 830 HOH HOH D . 
F 3 HOH 110 710 690 HOH HOH D . 
F 3 HOH 111 711 714 HOH HOH D . 
F 3 HOH 112 712 737 HOH HOH D . 
F 3 HOH 113 713 906 HOH HOH D . 
F 3 HOH 114 714 622 HOH HOH D . 
F 3 HOH 115 715 645 HOH HOH D . 
F 3 HOH 116 716 610 HOH HOH D . 
F 3 HOH 117 717 723 HOH HOH D . 
F 3 HOH 118 718 745 HOH HOH D . 
F 3 HOH 119 719 857 HOH HOH D . 
F 3 HOH 120 720 775 HOH HOH D . 
F 3 HOH 121 721 811 HOH HOH D . 
F 3 HOH 122 722 902 HOH HOH D . 
F 3 HOH 123 723 753 HOH HOH D . 
F 3 HOH 124 724 933 HOH HOH D . 
F 3 HOH 125 725 730 HOH HOH D . 
F 3 HOH 126 726 761 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 204 ? CD  ? A LYS 36  CD  
2  1 Y 1 A LYS 204 ? CE  ? A LYS 36  CE  
3  1 Y 1 A LYS 204 ? NZ  ? A LYS 36  NZ  
4  1 Y 1 A LYS 225 ? CD  ? A LYS 57  CD  
5  1 Y 1 A LYS 225 ? CE  ? A LYS 57  CE  
6  1 Y 1 A LYS 225 ? NZ  ? A LYS 57  NZ  
7  1 Y 1 A ARG 253 ? CD  ? A ARG 85  CD  
8  1 Y 1 A ARG 253 ? NE  ? A ARG 85  NE  
9  1 Y 1 A ARG 253 ? CZ  ? A ARG 85  CZ  
10 1 Y 1 A ARG 253 ? NH1 ? A ARG 85  NH1 
11 1 Y 1 A ARG 253 ? NH2 ? A ARG 85  NH2 
12 1 Y 1 D LYS 217 ? CG  ? B LYS 49  CG  
13 1 Y 1 D LYS 217 ? CD  ? B LYS 49  CD  
14 1 Y 1 D LYS 217 ? CE  ? B LYS 49  CE  
15 1 Y 1 D LYS 217 ? NZ  ? B LYS 49  NZ  
16 1 Y 1 D ARG 253 ? CD  ? B ARG 85  CD  
17 1 Y 1 D ARG 253 ? NE  ? B ARG 85  NE  
18 1 Y 1 D ARG 253 ? CZ  ? B ARG 85  CZ  
19 1 Y 1 D ARG 253 ? NH1 ? B ARG 85  NH1 
20 1 Y 1 D ARG 253 ? NH2 ? B ARG 85  NH2 
21 1 Y 1 D GLU 267 ? CG  ? B GLU 99  CG  
22 1 Y 1 D GLU 267 ? CD  ? B GLU 99  CD  
23 1 Y 1 D GLU 267 ? OE1 ? B GLU 99  OE1 
24 1 Y 1 D GLU 267 ? OE2 ? B GLU 99  OE2 
25 1 Y 1 D GLU 268 ? CG  ? B GLU 100 CG  
26 1 Y 1 D GLU 268 ? CD  ? B GLU 100 CD  
27 1 Y 1 D GLU 268 ? OE1 ? B GLU 100 OE1 
28 1 Y 1 D GLU 268 ? OE2 ? B GLU 100 OE2 
29 1 Y 1 D SER 274 ? OG  ? B SER 106 OG  
30 1 Y 1 D GLN 275 ? CG  ? B GLN 107 CG  
31 1 Y 1 D GLN 275 ? CD  ? B GLN 107 CD  
32 1 Y 1 D GLN 275 ? OE1 ? B GLN 107 OE1 
33 1 Y 1 D GLN 275 ? NE2 ? B GLN 107 NE2 
34 1 Y 1 D ASP 279 ? CG  ? B ASP 111 CG  
35 1 Y 1 D ASP 279 ? OD1 ? B ASP 111 OD1 
36 1 Y 1 D ASP 279 ? OD2 ? B ASP 111 OD2 
37 1 Y 1 D LYS 281 ? CD  ? B LYS 113 CD  
38 1 Y 1 D LYS 281 ? CE  ? B LYS 113 CE  
39 1 Y 1 D LYS 281 ? NZ  ? B LYS 113 NZ  
40 1 Y 1 D SER 286 ? OG  ? B SER 118 OG  
41 1 Y 1 D ASP 290 ? CG  ? B ASP 122 CG  
42 1 Y 1 D ASP 290 ? OD1 ? B ASP 122 OD1 
43 1 Y 1 D ASP 290 ? OD2 ? B ASP 122 OD2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP  ? ? ? .        4 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 5 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EP5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     41.84 
_cell.length_a_esd                 ? 
_cell.length_b                     185.324 
_cell.length_b_esd                 ? 
_cell.length_c                     128.391 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EP5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EP5 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.90 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          35.18 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '1.6% Ammonium Sulphate, 3% PEG 1K,10% glycerol, 24 well format Linbro plate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-02-01 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9119 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I04-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9119 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I04-1 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          14.6 
_reflns.entry_id                                       9EP5 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.64 
_reflns.d_resolution_low                               46.33 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     61821 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.15 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.175 
_reflns.pdbx_Rpim_I_all                                0.067 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.162 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
8.98 46.33 ? 40.0 ? ? ? ? 453  ? ? ? ? ? ? ? ? ? ? ? 11.7 1.11 ? ? 0.053 0.020 ? 1 1 0.999 ? ? 99.5  ? 0.050 ? ? ? ? ? ? ? ? ? 
1.64 1.67  ? 0.8  ? ? ? ? 3055 ? ? ? ? ? ? ? ? ? ? ? 13.3 0.90 ? ? 3.466 1.313 ? 2 1 0.467 ? ? 100.0 ? 3.203 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            1.469 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            0.567 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -2.035 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.374 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.924 
_refine.correlation_coeff_Fo_to_Fc_free          0.887 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9EP5 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.640 
_refine.ls_d_res_low                             46.33 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     61781 
_refine.ls_number_reflns_R_free                  3200 
_refine.ls_number_reflns_R_work                  58581 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.989 
_refine.ls_percent_reflns_R_free                 5.180 
_refine.ls_R_factor_all                          0.199 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2405 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1966 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.113 
_refine.pdbx_overall_ESU_R_Free                  0.114 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             2.710 
_refine.overall_SU_ML                            0.085 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.640 
_refine_hist.d_res_low                        46.33 
_refine_hist.number_atoms_solvent             464 
_refine_hist.number_atoms_total               4705 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4231 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         10 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  4380 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  3977 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.450  1.800  5996 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.543  1.752  9119 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.196  5.000  548  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 6.370  5.000  32   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.163 10.000 642  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.863 10.000 208  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.078  0.200  645  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  5396 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  1064 ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.210  0.200  467  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.182  0.200  2015 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.184  0.200  1130 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.078  0.200  1162 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.136  0.200  290  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.202  0.200  18   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.144  0.200  87   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.148  0.200  65   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.542  1.937  2189 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.541  1.937  2189 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.161  3.476  2738 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.160  3.475  2739 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 2.037  2.067  2191 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.035  2.064  2188 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.095  3.746  3258 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.093  3.740  3253 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 4.963  21.140 3817 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.965  21.163 3811 ? r_lrange_other                 ? ? 
'X-RAY DIFFRACTION' ? 0.077  0.050  9216 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.07749 ? 0.05009 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.07749 ? 0.05009 2 'Local ncs' ? A ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.640 1.683 . . 238 4291 100.0000 . . . . 0.461 . . . . . . . . . . . 0.451 
'X-RAY DIFFRACTION' 1.683 1.729 . . 238 4140 100.0000 . . . . 0.395 . . . . . . . . . . . 0.387 
'X-RAY DIFFRACTION' 1.729 1.779 . . 192 4069 99.9765  . . . . 0.334 . . . . . . . . . . . 0.338 
'X-RAY DIFFRACTION' 1.779 1.833 . . 212 3962 99.9761  . . . . 0.268 . . . . . . . . . . . 0.323 
'X-RAY DIFFRACTION' 1.833 1.893 . . 199 3851 100.0000 . . . . 0.226 . . . . . . . . . . . 0.242 
'X-RAY DIFFRACTION' 1.893 1.960 . . 208 3662 99.9742  . . . . 0.212 . . . . . . . . . . . 0.253 
'X-RAY DIFFRACTION' 1.960 2.034 . . 198 3568 100.0000 . . . . 0.185 . . . . . . . . . . . 0.218 
'X-RAY DIFFRACTION' 2.034 2.116 . . 194 3457 100.0000 . . . . 0.172 . . . . . . . . . . . 0.221 
'X-RAY DIFFRACTION' 2.116 2.210 . . 194 3315 100.0000 . . . . 0.166 . . . . . . . . . . . 0.184 
'X-RAY DIFFRACTION' 2.210 2.318 . . 165 3185 100.0000 . . . . 0.160 . . . . . . . . . . . 0.185 
'X-RAY DIFFRACTION' 2.318 2.443 . . 146 3011 100.0000 . . . . 0.144 . . . . . . . . . . . 0.211 
'X-RAY DIFFRACTION' 2.443 2.591 . . 174 2849 100.0000 . . . . 0.141 . . . . . . . . . . . 0.182 
'X-RAY DIFFRACTION' 2.591 2.769 . . 148 2688 100.0000 . . . . 0.137 . . . . . . . . . . . 0.183 
'X-RAY DIFFRACTION' 2.769 2.990 . . 121 2575 100.0000 . . . . 0.149 . . . . . . . . . . . 0.177 
'X-RAY DIFFRACTION' 2.990 3.274 . . 127 2318 100.0000 . . . . 0.178 . . . . . . . . . . . 0.215 
'X-RAY DIFFRACTION' 3.274 3.658 . . 127 2094 100.0000 . . . . 0.169 . . . . . . . . . . . 0.233 
'X-RAY DIFFRACTION' 3.658 4.220 . . 117 1893 100.0000 . . . . 0.150 . . . . . . . . . . . 0.175 
'X-RAY DIFFRACTION' 4.220 5.157 . . 79  1613 100.0000 . . . . 0.159 . . . . . . . . . . . 0.221 
'X-RAY DIFFRACTION' 5.157 7.249 . . 71  1277 100.0000 . . . . 0.254 . . . . . . . . . . . 0.312 
'X-RAY DIFFRACTION' 7.249 46.33 . . 52  764  100.0000 . . . . 0.513 . . . . . . . . . . . 0.704 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 A 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A GLN 29 . A GLN 300 . A GLN 197 A GLN 468 ? ? 
1 2 1 A GLN 29 . A GLN 300 . A GLN 197 A GLN 468 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9EP5 
_struct.title                        
'GH191 family Alpha-Galactosaminidase from Environmental sample (99.2% identity to Myxococcus fulvus enzyme)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EP5 
_struct_keywords.text            'GH114 family, crystal pathology, environmental sample, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9EP5 
_struct_ref.pdbx_db_accession          9EP5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9EP5 A 1 ? 300 ? 9EP5 169 ? 468 ? 169 468 
2 1 9EP5 D 1 ? 300 ? 9EP5 169 ? 468 ? 169 468 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,E 
2 1 B,D,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 31  ? VAL A 35  ? PRO A 199 VAL A 203 5 ? 5  
HELX_P HELX_P2  AA2 TYR A 45  ? LYS A 49  ? TYR A 213 LYS A 217 5 ? 5  
HELX_P HELX_P3  AA3 LEU A 50  ? SER A 56  ? LEU A 218 SER A 224 1 ? 7  
HELX_P HELX_P4  AA4 THR A 75  ? ARG A 85  ? THR A 243 ARG A 253 1 ? 11 
HELX_P HELX_P5  AA5 GLU A 104 ? VAL A 108 ? GLU A 272 VAL A 276 5 ? 5  
HELX_P HELX_P6  AA6 PRO A 109 ? ASP A 111 ? PRO A 277 ASP A 279 5 ? 3  
HELX_P HELX_P7  AA7 TRP A 133 ? ALA A 147 ? TRP A 301 ALA A 315 1 ? 15 
HELX_P HELX_P8  AA8 VAL A 158 ? ILE A 163 ? VAL A 326 ILE A 331 1 ? 6  
HELX_P HELX_P9  AA9 ASN A 171 ? ASN A 194 ? ASN A 339 ASN A 362 1 ? 24 
HELX_P HELX_P10 AB1 SER A 204 ? ASP A 210 ? SER A 372 ASP A 378 5 ? 7  
HELX_P HELX_P11 AB2 TYR A 213 ? ILE A 217 ? TYR A 381 ILE A 385 5 ? 5  
HELX_P HELX_P12 AB3 GLU A 235 ? ALA A 251 ? GLU A 403 ALA A 419 1 ? 17 
HELX_P HELX_P13 AB4 GLN A 263 ? ALA A 277 ? GLN A 431 ALA A 445 1 ? 15 
HELX_P HELX_P14 AB5 PRO B 31  ? VAL B 35  ? PRO D 199 VAL D 203 5 ? 5  
HELX_P HELX_P15 AB6 TYR B 45  ? LYS B 49  ? TYR D 213 LYS D 217 5 ? 5  
HELX_P HELX_P16 AB7 LEU B 50  ? SER B 56  ? LEU D 218 SER D 224 1 ? 7  
HELX_P HELX_P17 AB8 THR B 75  ? ARG B 85  ? THR D 243 ARG D 253 1 ? 11 
HELX_P HELX_P18 AB9 ARG B 102 ? VAL B 108 ? ARG D 270 VAL D 276 5 ? 7  
HELX_P HELX_P19 AC1 PRO B 109 ? ASP B 111 ? PRO D 277 ASP D 279 5 ? 3  
HELX_P HELX_P20 AC2 TRP B 133 ? ALA B 147 ? TRP D 301 ALA D 315 1 ? 15 
HELX_P HELX_P21 AC3 VAL B 158 ? ILE B 163 ? VAL D 326 ILE D 331 1 ? 6  
HELX_P HELX_P22 AC4 ASN B 171 ? ASN B 194 ? ASN D 339 ASN D 362 1 ? 24 
HELX_P HELX_P23 AC5 SER B 204 ? ASP B 210 ? SER D 372 ASP D 378 5 ? 7  
HELX_P HELX_P24 AC6 TYR B 213 ? ILE B 217 ? TYR D 381 ILE D 385 5 ? 5  
HELX_P HELX_P25 AC7 GLU B 235 ? ALA B 251 ? GLU D 403 ALA D 419 1 ? 17 
HELX_P HELX_P26 AC8 GLN B 263 ? ALA B 277 ? GLN D 431 ALA D 445 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 233 SG ? ? ? 1_555 A CYS 238 SG ? ? A CYS 401 A CYS 406 1_555 ? ? ? ? ? ? ? 2.035 ? ? 
disulf2 disulf ? ? B CYS 233 SG ? ? ? 1_555 B CYS 238 SG ? ? D CYS 401 D CYS 406 1_555 ? ? ? ? ? ? ? 2.050 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 233 ? CYS A 238 ? CYS A 401 ? 1_555 CYS A 406 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 233 ? CYS B 238 ? CYS D 401 ? 1_555 CYS D 406 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 39  ? TYR A 40  ? THR A 207 TYR A 208 
AA1 2 LEU A 60  ? GLU A 64  ? LEU A 228 GLU A 232 
AA1 3 GLN A 88  ? GLU A 94  ? GLN A 256 GLU A 262 
AA1 4 GLY A 151 ? ASP A 155 ? GLY A 319 ASP A 323 
AA1 5 LYS A 198 ? PRO A 201 ? LYS A 366 PRO A 369 
AA2 1 ALA A 97  ? GLU A 99  ? ALA A 265 GLU A 267 
AA2 2 GLU A 123 ? VAL A 126 ? GLU A 291 VAL A 294 
AA2 3 LYS A 113 ? PRO A 116 ? LYS A 281 PRO A 284 
AA3 1 VAL A 231 ? ALA A 232 ? VAL A 399 ALA A 400 
AA3 2 GLY A 219 ? SER A 228 ? GLY A 387 SER A 396 
AA3 3 LEU A 254 ? TYR A 260 ? LEU A 422 TYR A 428 
AA3 4 VAL A 280 ? THR A 284 ? VAL A 448 THR A 452 
AA4 1 PHE B 38  ? TYR B 40  ? PHE D 206 TYR D 208 
AA4 2 LEU B 60  ? GLU B 64  ? LEU D 228 GLU D 232 
AA4 3 GLN B 88  ? GLU B 94  ? GLN D 256 GLU D 262 
AA4 4 GLY B 151 ? ASP B 155 ? GLY D 319 ASP D 323 
AA4 5 LYS B 198 ? PRO B 201 ? LYS D 366 PRO D 369 
AA5 1 ALA B 97  ? GLU B 99  ? ALA D 265 GLU D 267 
AA5 2 TRP B 120 ? VAL B 126 ? TRP D 288 VAL D 294 
AA5 3 LYS B 113 ? VAL B 117 ? LYS D 281 VAL D 285 
AA6 1 VAL B 231 ? ALA B 232 ? VAL D 399 ALA D 400 
AA6 2 GLY B 219 ? SER B 228 ? GLY D 387 SER D 396 
AA6 3 LEU B 254 ? TYR B 260 ? LEU D 422 TYR D 428 
AA6 4 VAL B 280 ? THR B 284 ? VAL D 448 THR D 452 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 39  ? N THR A 207 O LEU A 60  ? O LEU A 228 
AA1 2 3 N VAL A 63  ? N VAL A 231 O TYR A 92  ? O TYR A 260 
AA1 3 4 N ALA A 91  ? N ALA A 259 O TYR A 153 ? O TYR A 321 
AA1 4 5 N CYS A 152 ? N CYS A 320 O LYS A 198 ? O LYS A 366 
AA2 1 2 N ILE A 98  ? N ILE A 266 O GLN A 124 ? O GLN A 292 
AA2 2 3 O TYR A 125 ? O TYR A 293 N GLY A 115 ? N GLY A 283 
AA3 1 2 O VAL A 231 ? O VAL A 399 N SER A 228 ? N SER A 396 
AA3 2 3 N MET A 222 ? N MET A 390 O THR A 258 ? O THR A 426 
AA3 3 4 N VAL A 255 ? N VAL A 423 O VAL A 280 ? O VAL A 448 
AA4 1 2 N THR B 39  ? N THR D 207 O LEU B 60  ? O LEU D 228 
AA4 2 3 N VAL B 63  ? N VAL D 231 O TYR B 92  ? O TYR D 260 
AA4 3 4 N ALA B 91  ? N ALA D 259 O TYR B 153 ? O TYR D 321 
AA4 4 5 N CYS B 152 ? N CYS D 320 O LYS B 198 ? O LYS D 366 
AA5 1 2 N ILE B 98  ? N ILE D 266 O GLN B 124 ? O GLN D 292 
AA5 2 3 O TYR B 125 ? O TYR D 293 N GLY B 115 ? N GLY D 283 
AA6 1 2 O VAL B 231 ? O VAL D 399 N SER B 228 ? N SER D 396 
AA6 2 3 N MET B 222 ? N MET D 390 O THR B 258 ? O THR D 426 
AA6 3 4 N VAL B 255 ? N VAL D 423 O VAL B 280 ? O VAL D 448 
# 
_pdbx_entry_details.entry_id                   9EP5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 238 ? ? -133.82 -97.99  
2 1 THR A 338 ? ? -126.45 -119.79 
3 1 ASN A 371 ? ? 63.74   -166.19 
4 1 TYR A 394 ? ? -121.38 -55.62  
5 1 SER D 238 ? ? -132.92 -103.98 
6 1 THR D 338 ? ? -126.92 -121.40 
7 1 ASN D 371 ? ? 69.38   -173.18 
8 1 TYR D 394 ? ? -122.47 -56.33  
9 1 THR D 452 ? ? -153.71 -159.89 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 270 ? ? 0.079 'SIDE CHAIN' 
2 1 ARG A 454 ? ? 0.078 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 610 ? E HOH . 
2 1 A HOH 831 ? E HOH . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ASP 169 ? A ASP 1  
2  1 Y 1 A ALA 170 ? A ALA 2  
3  1 Y 1 A GLY 171 ? A GLY 3  
4  1 Y 1 A THR 172 ? A THR 4  
5  1 Y 1 A PRO 173 ? A PRO 5  
6  1 Y 1 A THR 174 ? A THR 6  
7  1 Y 1 A ASP 175 ? A ASP 7  
8  1 Y 1 A ALA 176 ? A ALA 8  
9  1 Y 1 A GLY 177 ? A GLY 9  
10 1 Y 1 A THR 178 ? A THR 10 
11 1 Y 1 A PRO 179 ? A PRO 11 
12 1 Y 1 A THR 180 ? A THR 12 
13 1 Y 1 A ASP 181 ? A ASP 13 
14 1 Y 1 A ALA 182 ? A ALA 14 
15 1 Y 1 A GLY 183 ? A GLY 15 
16 1 Y 1 A THR 184 ? A THR 16 
17 1 Y 1 A PRO 185 ? A PRO 17 
18 1 Y 1 A THR 186 ? A THR 18 
19 1 Y 1 A ASP 187 ? A ASP 19 
20 1 Y 1 A ALA 188 ? A ALA 20 
21 1 Y 1 A GLY 189 ? A GLY 21 
22 1 Y 1 A THR 190 ? A THR 22 
23 1 Y 1 A PRO 191 ? A PRO 23 
24 1 Y 1 A THR 192 ? A THR 24 
25 1 Y 1 A ASP 193 ? A ASP 25 
26 1 Y 1 A ALA 194 ? A ALA 26 
27 1 Y 1 A GLY 195 ? A GLY 27 
28 1 Y 1 A THR 196 ? A THR 28 
29 1 Y 1 D ASP 169 ? B ASP 1  
30 1 Y 1 D ALA 170 ? B ALA 2  
31 1 Y 1 D GLY 171 ? B GLY 3  
32 1 Y 1 D THR 172 ? B THR 4  
33 1 Y 1 D PRO 173 ? B PRO 5  
34 1 Y 1 D THR 174 ? B THR 6  
35 1 Y 1 D ASP 175 ? B ASP 7  
36 1 Y 1 D ALA 176 ? B ALA 8  
37 1 Y 1 D GLY 177 ? B GLY 9  
38 1 Y 1 D THR 178 ? B THR 10 
39 1 Y 1 D PRO 179 ? B PRO 11 
40 1 Y 1 D THR 180 ? B THR 12 
41 1 Y 1 D ASP 181 ? B ASP 13 
42 1 Y 1 D ALA 182 ? B ALA 14 
43 1 Y 1 D GLY 183 ? B GLY 15 
44 1 Y 1 D THR 184 ? B THR 16 
45 1 Y 1 D PRO 185 ? B PRO 17 
46 1 Y 1 D THR 186 ? B THR 18 
47 1 Y 1 D ASP 187 ? B ASP 19 
48 1 Y 1 D ALA 188 ? B ALA 20 
49 1 Y 1 D GLY 189 ? B GLY 21 
50 1 Y 1 D THR 190 ? B THR 22 
51 1 Y 1 D PRO 191 ? B PRO 23 
52 1 Y 1 D THR 192 ? B THR 24 
53 1 Y 1 D ASP 193 ? B ASP 25 
54 1 Y 1 D ALA 194 ? B ALA 26 
55 1 Y 1 D GLY 195 ? B GLY 27 
56 1 Y 1 D THR 196 ? B THR 28 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
SO4 S    S N N 304 
SO4 O1   O N N 305 
SO4 O2   O N N 306 
SO4 O3   O N N 307 
SO4 O4   O N N 308 
THR N    N N N 309 
THR CA   C N S 310 
THR C    C N N 311 
THR O    O N N 312 
THR CB   C N R 313 
THR OG1  O N N 314 
THR CG2  C N N 315 
THR OXT  O N N 316 
THR H    H N N 317 
THR H2   H N N 318 
THR HA   H N N 319 
THR HB   H N N 320 
THR HG1  H N N 321 
THR HG21 H N N 322 
THR HG22 H N N 323 
THR HG23 H N N 324 
THR HXT  H N N 325 
TRP N    N N N 326 
TRP CA   C N S 327 
TRP C    C N N 328 
TRP O    O N N 329 
TRP CB   C N N 330 
TRP CG   C Y N 331 
TRP CD1  C Y N 332 
TRP CD2  C Y N 333 
TRP NE1  N Y N 334 
TRP CE2  C Y N 335 
TRP CE3  C Y N 336 
TRP CZ2  C Y N 337 
TRP CZ3  C Y N 338 
TRP CH2  C Y N 339 
TRP OXT  O N N 340 
TRP H    H N N 341 
TRP H2   H N N 342 
TRP HA   H N N 343 
TRP HB2  H N N 344 
TRP HB3  H N N 345 
TRP HD1  H N N 346 
TRP HE1  H N N 347 
TRP HE3  H N N 348 
TRP HZ2  H N N 349 
TRP HZ3  H N N 350 
TRP HH2  H N N 351 
TRP HXT  H N N 352 
TYR N    N N N 353 
TYR CA   C N S 354 
TYR C    C N N 355 
TYR O    O N N 356 
TYR CB   C N N 357 
TYR CG   C Y N 358 
TYR CD1  C Y N 359 
TYR CD2  C Y N 360 
TYR CE1  C Y N 361 
TYR CE2  C Y N 362 
TYR CZ   C Y N 363 
TYR OH   O N N 364 
TYR OXT  O N N 365 
TYR H    H N N 366 
TYR H2   H N N 367 
TYR HA   H N N 368 
TYR HB2  H N N 369 
TYR HB3  H N N 370 
TYR HD1  H N N 371 
TYR HD2  H N N 372 
TYR HE1  H N N 373 
TYR HE2  H N N 374 
TYR HH   H N N 375 
TYR HXT  H N N 376 
VAL N    N N N 377 
VAL CA   C N S 378 
VAL C    C N N 379 
VAL O    O N N 380 
VAL CB   C N N 381 
VAL CG1  C N N 382 
VAL CG2  C N N 383 
VAL OXT  O N N 384 
VAL H    H N N 385 
VAL H2   H N N 386 
VAL HA   H N N 387 
VAL HB   H N N 388 
VAL HG11 H N N 389 
VAL HG12 H N N 390 
VAL HG13 H N N 391 
VAL HG21 H N N 392 
VAL HG22 H N N 393 
VAL HG23 H N N 394 
VAL HXT  H N N 395 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SO4 S   O1   doub N N 290 
SO4 S   O2   doub N N 291 
SO4 S   O3   sing N N 292 
SO4 S   O4   sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2aam 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_related_exp_data_set.data_reference       10.5281/zenodo.10936960 
_pdbx_related_exp_data_set.data_set_type        'diffraction image data' 
_pdbx_related_exp_data_set.details              ? 
_pdbx_related_exp_data_set.metadata_reference   ? 
_pdbx_related_exp_data_set.ordinal              1 
# 
_atom_sites.entry_id                    9EP5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.023901 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.005396 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007789 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0298   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N    . GLN A 1 29  ? 13.614  23.456  29.498  1     42.396 ? 197 GLN A N    1 ? 
ATOM   2    C CA   . GLN A 1 29  ? 13.046  22.623  28.401  1     37.216 ? 197 GLN A CA   1 ? 
ATOM   3    C C    . GLN A 1 29  ? 11.6    23.045  28.152  1     33.871 ? 197 GLN A C    1 ? 
ATOM   4    O O    . GLN A 1 29  ? 10.853  23.347  29.082  1     31.142 ? 197 GLN A O    1 ? 
ATOM   5    C CB   . GLN A 1 29  ? 13.09   21.11   28.678  1     36.472 ? 197 GLN A CB   1 ? 
ATOM   6    C CG   . GLN A 1 29  ? 14.487  20.496  28.563  1     36.938 ? 197 GLN A CG   1 ? 
ATOM   7    C CD   . GLN A 1 29  ? 14.512  18.977  28.524  1     40.635 ? 197 GLN A CD   1 ? 
ATOM   8    O OE1  . GLN A 1 29  ? 14.623  18.265  29.539  1     42.311 ? 197 GLN A OE1  1 ? 
ATOM   9    N NE2  . GLN A 1 29  ? 14.485  18.463  27.306  1     31.617 ? 197 GLN A NE2  1 ? 
ATOM   10   H H    . GLN A 1 29  ? 14.469  23.215  29.655  1     40.709 ? 197 GLN A H    1 c 
ATOM   11   H HA   . GLN A 1 29  ? 13.572  22.8    27.585  1     37.135 ? 197 GLN A HA   1 c 
ATOM   12   H HB2  . GLN A 1 29  ? 12.746  20.947  29.581  1     36.741 ? 197 GLN A HB2  1 c 
ATOM   13   H HB3  . GLN A 1 29  ? 12.493  20.656  28.047  1     36.728 ? 197 GLN A HB3  1 c 
ATOM   14   H HG2  . GLN A 1 29  ? 14.917  20.834  27.748  1     37.604 ? 197 GLN A HG2  1 c 
ATOM   15   H HG3  . GLN A 1 29  ? 15.028  20.793  29.325  1     37.64  ? 197 GLN A HG3  1 c 
ATOM   16   H HE21 . GLN A 1 29  ? 14.984  17.758  27.108  1     33.992 ? 197 GLN A HE21 1 c 
ATOM   17   H HE22 . GLN A 1 29  ? 13.961  18.829  26.696  1     33.883 ? 197 GLN A HE22 1 c 
ATOM   18   N N    . VAL A 1 30  ? 11.193  22.981  26.881  1     27.756 ? 198 VAL A N    1 ? 
ATOM   19   C CA   . VAL A 1 30  ? 9.795   23.058  26.534  1     27.376 ? 198 VAL A CA   1 ? 
ATOM   20   C C    . VAL A 1 30  ? 9.104   21.858  27.172  1     31.56  ? 198 VAL A C    1 ? 
ATOM   21   O O    . VAL A 1 30  ? 9.482   20.727  26.922  1     30.479 ? 198 VAL A O    1 ? 
ATOM   22   C CB   . VAL A 1 30  ? 9.55    23.07   25.019  1     28.308 ? 198 VAL A CB   1 ? 
ATOM   23   C CG1  . VAL A 1 30  ? 8.052   23.104  24.696  1     28.233 ? 198 VAL A CG1  1 ? 
ATOM   24   C CG2  . VAL A 1 30  ? 10.274  24.217  24.325  1     30.697 ? 198 VAL A CG2  1 ? 
ATOM   25   H H    . VAL A 1 30  ? 11.809  22.868  26.215  1     29.136 ? 198 VAL A H    1 c 
ATOM   26   H HA   . VAL A 1 30  ? 9.434   23.878  26.907  1     28.454 ? 198 VAL A HA   1 c 
ATOM   27   H HB   . VAL A 1 30  ? 9.914   22.226  24.661  1     28.547 ? 198 VAL A HB   1 c 
ATOM   28   H HG11 . VAL A 1 30  ? 7.584   23.618  25.375  1     28.272 ? 198 VAL A HG11 1 c 
ATOM   29   H HG12 . VAL A 1 30  ? 7.702   22.197  24.68   1     28.273 ? 198 VAL A HG12 1 c 
ATOM   30   H HG13 . VAL A 1 30  ? 7.912   23.517  23.827  1     28.286 ? 198 VAL A HG13 1 c 
ATOM   31   H HG21 . VAL A 1 30  ? 10.037  24.229  23.383  1     29.916 ? 198 VAL A HG21 1 c 
ATOM   32   H HG22 . VAL A 1 30  ? 11.234  24.099  24.411  1     29.95  ? 198 VAL A HG22 1 c 
ATOM   33   H HG23 . VAL A 1 30  ? 10.014  25.059  24.733  1     29.958 ? 198 VAL A HG23 1 c 
ATOM   34   N N    . PRO A 1 31  ? 8.035   22.055  27.966  1     28.557 ? 199 PRO A N    1 ? 
ATOM   35   C CA   . PRO A 1 31  ? 7.269   20.944  28.517  1     28.487 ? 199 PRO A CA   1 ? 
ATOM   36   C C    . PRO A 1 31  ? 6.627   20.102  27.429  1     30.914 ? 199 PRO A C    1 ? 
ATOM   37   O O    . PRO A 1 31  ? 6.276   20.641  26.372  1     27.302 ? 199 PRO A O    1 ? 
ATOM   38   C CB   . PRO A 1 31  ? 6.2     21.635  29.37   1     34.029 ? 199 PRO A CB   1 ? 
ATOM   39   C CG   . PRO A 1 31  ? 6.845   22.954  29.713  1     35.488 ? 199 PRO A CG   1 ? 
ATOM   40   C CD   . PRO A 1 31  ? 7.559   23.366  28.442  1     34.435 ? 199 PRO A CD   1 ? 
ATOM   41   H HA   . PRO A 1 31  ? 7.854   20.387  29.09   1     29.849 ? 199 PRO A HA   1 c 
ATOM   42   H HB2  . PRO A 1 31  ? 5.367   21.77   28.859  1     33.01  ? 199 PRO A HB2  1 c 
ATOM   43   H HB3  . PRO A 1 31  ? 6.004   21.113  30.184  1     33.018 ? 199 PRO A HB3  1 c 
ATOM   44   H HG2  . PRO A 1 31  ? 6.17    23.619  29.964  1     34.913 ? 199 PRO A HG2  1 c 
ATOM   45   H HG3  . PRO A 1 31  ? 7.48    22.851  30.452  1     34.913 ? 199 PRO A HG3  1 c 
ATOM   46   H HD2  . PRO A 1 31  ? 6.941   23.783  27.8    1     33.183 ? 199 PRO A HD2  1 c 
ATOM   47   H HD3  . PRO A 1 31  ? 8.3     23.978  28.641  1     33.12  ? 199 PRO A HD3  1 c 
ATOM   48   N N    . TRP A 1 32  ? 6.483   18.795  27.717  1     26.116 ? 200 TRP A N    1 ? 
ATOM   49   C CA   . TRP A 1 32  ? 5.848   17.845  26.82   1     24.501 ? 200 TRP A CA   1 ? 
ATOM   50   C C    . TRP A 1 32  ? 4.514   18.356  26.31   1     26.22  ? 200 TRP A C    1 ? 
ATOM   51   O O    . TRP A 1 32  ? 4.256   18.292  25.115  1     25.786 ? 200 TRP A O    1 ? 
ATOM   52   C CB   . TRP A 1 32  ? 5.645   16.493  27.515  1     24.098 ? 200 TRP A CB   1 ? 
ATOM   53   C CG   . TRP A 1 32  ? 5.197   15.359  26.632  1     20.243 ? 200 TRP A CG   1 ? 
ATOM   54   C CD1  . TRP A 1 32  ? 3.987   14.739  26.624  1     20.847 ? 200 TRP A CD1  1 ? 
ATOM   55   C CD2  . TRP A 1 32  ? 6.011   14.656  25.673  1     17.602 ? 200 TRP A CD2  1 ? 
ATOM   56   N NE1  . TRP A 1 32  ? 3.985   13.695  25.742  1     21.879 ? 200 TRP A NE1  1 ? 
ATOM   57   C CE2  . TRP A 1 32  ? 5.211   13.636  25.13   1     19.563 ? 200 TRP A CE2  1 ? 
ATOM   58   C CE3  . TRP A 1 32  ? 7.335   14.813  25.227  1     19.341 ? 200 TRP A CE3  1 ? 
ATOM   59   C CZ2  . TRP A 1 32  ? 5.689   12.758  24.178  1     19.208 ? 200 TRP A CZ2  1 ? 
ATOM   60   C CZ3  . TRP A 1 32  ? 7.802   13.928  24.27   1     16.394 ? 200 TRP A CZ3  1 ? 
ATOM   61   C CH2  . TRP A 1 32  ? 6.982   12.942  23.736  1     17.069 ? 200 TRP A CH2  1 ? 
ATOM   62   H H    . TRP A 1 32  ? 6.796   18.488  28.519  1     26.784 ? 200 TRP A H    1 c 
ATOM   63   H HA   . TRP A 1 32  ? 6.45    17.705  26.04   1     25.048 ? 200 TRP A HA   1 c 
ATOM   64   H HB2  . TRP A 1 32  ? 6.489   16.239  27.944  1     23.256 ? 200 TRP A HB2  1 c 
ATOM   65   H HB3  . TRP A 1 32  ? 4.985   16.612  28.231  1     23.25  ? 200 TRP A HB3  1 c 
ATOM   66   H HD1  . TRP A 1 32  ? 3.256   14.972  27.174  1     20.924 ? 200 TRP A HD1  1 c 
ATOM   67   H HE1  . TRP A 1 32  ? 3.304   13.178  25.569  1     21.043 ? 200 TRP A HE1  1 c 
ATOM   68   H HE3  . TRP A 1 32  ? 7.887   15.493  25.573  1     18.231 ? 200 TRP A HE3  1 c 
ATOM   69   H HZ2  . TRP A 1 32  ? 5.141   12.08   23.821  1     18.76  ? 200 TRP A HZ2  1 c 
ATOM   70   H HZ3  . TRP A 1 32  ? 8.682   14.02   23.945  1     17.24  ? 200 TRP A HZ3  1 c 
ATOM   71   H HH2  . TRP A 1 32  ? 7.334   12.352  23.092  1     17.415 ? 200 TRP A HH2  1 c 
ATOM   72   N N    . SER A 1 33  ? 3.713   18.94   27.225  1     26.685 ? 201 SER A N    1 ? 
ATOM   73   C CA   . SER A 1 33  ? 2.375   19.4    26.897  1     27.806 ? 201 SER A CA   1 ? 
ATOM   74   C C    . SER A 1 33  ? 2.39    20.625  25.976  1     23.859 ? 201 SER A C    1 ? 
ATOM   75   O O    . SER A 1 33  ? 1.348   20.974  25.445  1     28.873 ? 201 SER A O    1 ? 
ATOM   76   C CB   . SER A 1 33  ? 1.592   19.742  28.166  1     30.78  ? 201 SER A CB   1 ? 
ATOM   77   O OG   . SER A 1 33  ? 2.317   20.746  28.874  1     34.405 ? 201 SER A OG   1 ? 
ATOM   78   H H    . SER A 1 33  ? 4.009   19.04   28.084  1     26.845 ? 201 SER A H    1 c 
ATOM   79   H HA   . SER A 1 33  ? 1.904   18.666  26.427  1     27.311 ? 201 SER A HA   1 c 
ATOM   80   H HB2  . SER A 1 33  ? 0.705   20.075  27.929  1     30.853 ? 201 SER A HB2  1 c 
ATOM   81   H HB3  . SER A 1 33  ? 1.497   18.945  28.721  1     30.895 ? 201 SER A HB3  1 c 
ATOM   82   N N    A ASN A 1 34  ? 3.532   21.296  25.814  0.5   23.466 ? 202 ASN A N    1 ? 
ATOM   83   N N    B ASN A 1 34  ? 3.54    21.28   25.813  0.5   23.717 ? 202 ASN A N    1 ? 
ATOM   84   C CA   A ASN A 1 34  ? 3.552   22.482  24.965  0.5   25.135 ? 202 ASN A CA   1 ? 
ATOM   85   C CA   B ASN A 1 34  ? 3.607   22.495  25.012  0.5   25.784 ? 202 ASN A CA   1 ? 
ATOM   86   C C    A ASN A 1 34  ? 4.438   22.293  23.738  0.5   23.311 ? 202 ASN A C    1 ? 
ATOM   87   C C    B ASN A 1 34  ? 4.44    22.295  23.745  0.5   23.554 ? 202 ASN A C    1 ? 
ATOM   88   O O    A ASN A 1 34  ? 4.771   23.266  23.076  0.5   24.414 ? 202 ASN A O    1 ? 
ATOM   89   O O    B ASN A 1 34  ? 4.754   23.267  23.073  0.5   24.65  ? 202 ASN A O    1 ? 
ATOM   90   C CB   A ASN A 1 34  ? 3.999   23.735  25.713  0.5   25.87  ? 202 ASN A CB   1 ? 
ATOM   91   C CB   B ASN A 1 34  ? 4.186   23.641  25.839  0.5   26.319 ? 202 ASN A CB   1 ? 
ATOM   92   C CG   A ASN A 1 34  ? 3.589   24.973  24.945  0.5   27.002 ? 202 ASN A CG   1 ? 
ATOM   93   C CG   B ASN A 1 34  ? 3.317   23.973  27.025  0.5   29.06  ? 202 ASN A CG   1 ? 
ATOM   94   O OD1  A ASN A 1 34  ? 2.453   25.061  24.461  0.5   30.153 ? 202 ASN A OD1  1 ? 
ATOM   95   O OD1  B ASN A 1 34  ? 2.188   23.482  27.132  0.5   30.884 ? 202 ASN A OD1  1 ? 
ATOM   96   N ND2  A ASN A 1 34  ? 4.503   25.909  24.778  0.5   28.262 ? 202 ASN A ND2  1 ? 
ATOM   97   N ND2  B ASN A 1 34  ? 3.805   24.83   27.909  0.5   32.303 ? 202 ASN A ND2  1 ? 
ATOM   98   H H    A ASN A 1 34  ? 4.294   21.046  26.249  0.5   23.992 ? 202 ASN A H    1 c 
ATOM   99   H H    B ASN A 1 34  ? 4.298   20.99   26.229  0.5   24.288 ? 202 ASN A H    1 c 
ATOM   100  H HA   A ASN A 1 34  ? 2.639   22.654  24.645  0.5   24.615 ? 202 ASN A HA   1 c 
ATOM   101  H HA   B ASN A 1 34  ? 2.698   22.756  24.746  0.5   25.065 ? 202 ASN A HA   1 c 
ATOM   102  H HB2  A ASN A 1 34  ? 3.59    23.75   26.601  0.5   25.955 ? 202 ASN A HB2  1 c 
ATOM   103  H HB2  B ASN A 1 34  ? 5.078   23.392  26.153  0.5   26.802 ? 202 ASN A HB2  1 c 
ATOM   104  H HB3  A ASN A 1 34  ? 4.971   23.723  25.82   0.5   25.955 ? 202 ASN A HB3  1 c 
ATOM   105  H HB3  B ASN A 1 34  ? 4.274   24.433  25.273  0.5   26.802 ? 202 ASN A HB3  1 c 
ATOM   106  H HD21 A ASN A 1 34  ? 4.302   26.649  24.332  0.5   27.868 ? 202 ASN A HD21 1 c 
ATOM   107  H HD21 B ASN A 1 34  ? 3.329   25.046  28.626  0.5   31.268 ? 202 ASN A HD21 1 c 
ATOM   108  H HD22 A ASN A 1 34  ? 5.317   25.797  25.113  0.5   27.868 ? 202 ASN A HD22 1 c 
ATOM   109  H HD22 B ASN A 1 34  ? 4.607   25.187  27.784  0.5   31.268 ? 202 ASN A HD22 1 c 
ATOM   110  N N    . VAL A 1 35  ? 4.792   21.051  23.404  1     22.123 ? 203 VAL A N    1 ? 
ATOM   111  C CA   . VAL A 1 35  ? 5.561   20.784  22.185  1     20.524 ? 203 VAL A CA   1 ? 
ATOM   112  C C    . VAL A 1 35  ? 4.692   21.121  20.974  1     19.039 ? 203 VAL A C    1 ? 
ATOM   113  O O    . VAL A 1 35  ? 3.6     20.578  20.812  1     20.347 ? 203 VAL A O    1 ? 
ATOM   114  C CB   . VAL A 1 35  ? 6.069   19.332  22.14   1     21.587 ? 203 VAL A CB   1 ? 
ATOM   115  C CG1  . VAL A 1 35  ? 6.517   18.91   20.743  1     19.904 ? 203 VAL A CG1  1 ? 
ATOM   116  C CG2  . VAL A 1 35  ? 7.202   19.119  23.141  1     19.913 ? 203 VAL A CG2  1 ? 
ATOM   117  H H    A VAL A 1 35  ? 4.553   20.352  23.943  0.5   22.017 ? 203 VAL A H    1 c 
ATOM   118  H H    B VAL A 1 35  ? 4.551   20.351  23.94   0.5   22.071 ? 203 VAL A H    1 c 
ATOM   119  H HA   . VAL A 1 35  ? 6.341   21.373  22.183  1     20.772 ? 203 VAL A HA   1 c 
ATOM   120  H HB   . VAL A 1 35  ? 5.318   18.75   22.403  1     20.767 ? 203 VAL A HB   1 c 
ATOM   121  H HG11 . VAL A 1 35  ? 6.992   19.644  20.317  1     20.375 ? 203 VAL A HG11 1 c 
ATOM   122  H HG12 . VAL A 1 35  ? 5.741   18.671  20.208  1     20.375 ? 203 VAL A HG12 1 c 
ATOM   123  H HG13 . VAL A 1 35  ? 7.109   18.142  20.81   1     20.379 ? 203 VAL A HG13 1 c 
ATOM   124  H HG21 . VAL A 1 35  ? 7.434   18.176  23.173  1     20.392 ? 203 VAL A HG21 1 c 
ATOM   125  H HG22 . VAL A 1 35  ? 6.915   19.411  24.023  1     20.392 ? 203 VAL A HG22 1 c 
ATOM   126  H HG23 . VAL A 1 35  ? 7.979   19.635  22.866  1     20.392 ? 203 VAL A HG23 1 c 
ATOM   127  N N    . LYS A 1 36  ? 5.184   21.998  20.114  1     19.497 ? 204 LYS A N    1 ? 
ATOM   128  C CA   . LYS A 1 36  ? 4.428   22.49   18.973  1     19.773 ? 204 LYS A CA   1 ? 
ATOM   129  C C    . LYS A 1 36  ? 5.185   22.366  17.641  1     20.823 ? 204 LYS A C    1 ? 
ATOM   130  O O    . LYS A 1 36  ? 4.617   22.72   16.605  1     19.971 ? 204 LYS A O    1 ? 
ATOM   131  C CB   . LYS A 1 36  ? 4       23.941  19.216  1     21.924 ? 204 LYS A CB   1 ? 
ATOM   132  C CG   . LYS A 1 36  ? 2.881   24.13   20.274  1     24.527 ? 204 LYS A CG   1 ? 
ATOM   133  H H    . LYS A 1 36  ? 6.016   22.345  20.265  1     19.46  ? 204 LYS A H    1 c 
ATOM   134  H HA   . LYS A 1 36  ? 3.602   21.949  18.891  1     20.301 ? 204 LYS A HA   1 c 
ATOM   135  H HB2  . LYS A 1 36  ? 4.785   24.454  19.504  1     21.958 ? 204 LYS A HB2  1 c 
ATOM   136  H HB3  . LYS A 1 36  ? 3.689   24.328  18.37   1     21.945 ? 204 LYS A HB3  1 c 
ATOM   137  N N    . SER A 1 37  ? 6.434   21.877  17.68   1     18.427 ? 205 SER A N    1 ? 
ATOM   138  C CA   . SER A 1 37  ? 7.264   21.697  16.496  1     20.265 ? 205 SER A CA   1 ? 
ATOM   139  C C    . SER A 1 37  ? 8.299   20.636  16.803  1     19.337 ? 205 SER A C    1 ? 
ATOM   140  O O    . SER A 1 37  ? 8.656   20.462  17.97   1     17.868 ? 205 SER A O    1 ? 
ATOM   141  C CB   . SER A 1 37  ? 7.904   22.995  16.1    1     19.648 ? 205 SER A CB   1 ? 
ATOM   142  O OG   . SER A 1 37  ? 8.795   23.428  17.119  1     19.688 ? 205 SER A OG   1 ? 
ATOM   143  H H    . SER A 1 37  ? 6.789   21.637  18.486  1     19.388 ? 205 SER A H    1 c 
ATOM   144  H HA   . SER A 1 37  ? 6.693   21.378  15.751  1     19.609 ? 205 SER A HA   1 c 
ATOM   145  H HB2  . SER A 1 37  ? 8.394   22.876  15.265  1     19.785 ? 205 SER A HB2  1 c 
ATOM   146  H HB3  . SER A 1 37  ? 7.213   23.67   15.961  1     19.798 ? 205 SER A HB3  1 c 
ATOM   147  N N    . PHE A 1 38  ? 8.752   19.901  15.782  1     17.743 ? 206 PHE A N    1 ? 
ATOM   148  C CA   . PHE A 1 38  ? 9.822   18.944  15.965  1     16.532 ? 206 PHE A CA   1 ? 
ATOM   149  C C    . PHE A 1 38  ? 10.6    18.745  14.671  1     16.938 ? 206 PHE A C    1 ? 
ATOM   150  O O    . PHE A 1 38  ? 10.103  19.024  13.577  1     15.858 ? 206 PHE A O    1 ? 
ATOM   151  C CB   . PHE A 1 38  ? 9.27    17.605  16.454  1     14.437 ? 206 PHE A CB   1 ? 
ATOM   152  C CG   . PHE A 1 38  ? 8.583   16.741  15.406  1     14.19  ? 206 PHE A CG   1 ? 
ATOM   153  C CD1  . PHE A 1 38  ? 7.279   17.033  14.99   1     14.884 ? 206 PHE A CD1  1 ? 
ATOM   154  C CD2  . PHE A 1 38  ? 9.239   15.679  14.801  1     14.075 ? 206 PHE A CD2  1 ? 
ATOM   155  C CE1  . PHE A 1 38  ? 6.651   16.261  14.028  1     15.901 ? 206 PHE A CE1  1 ? 
ATOM   156  C CE2  . PHE A 1 38  ? 8.602   14.908  13.84   1     14.707 ? 206 PHE A CE2  1 ? 
ATOM   157  C CZ   . PHE A 1 38  ? 7.295   15.2    13.444  1     16.052 ? 206 PHE A CZ   1 ? 
ATOM   158  H H    . PHE A 1 38  ? 8.382   20      14.952  1     17.846 ? 206 PHE A H    1 c 
ATOM   159  H HA   . PHE A 1 38  ? 10.439  19.3    16.649  1     16.456 ? 206 PHE A HA   1 c 
ATOM   160  H HB2  . PHE A 1 38  ? 10.013  17.093  16.842  1     14.853 ? 206 PHE A HB2  1 c 
ATOM   161  H HB3  . PHE A 1 38  ? 8.63    17.783  17.179  1     14.853 ? 206 PHE A HB3  1 c 
ATOM   162  H HD1  . PHE A 1 38  ? 6.819   17.757  15.381  1     14.972 ? 206 PHE A HD1  1 c 
ATOM   163  H HD2  . PHE A 1 38  ? 10.121  15.467  15.062  1     14.274 ? 206 PHE A HD2  1 c 
ATOM   164  H HE1  . PHE A 1 38  ? 5.771   16.469  13.769  1     15.67  ? 206 PHE A HE1  1 c 
ATOM   165  H HE2  . PHE A 1 38  ? 9.058   14.181  13.447  1     14.859 ? 206 PHE A HE2  1 c 
ATOM   166  H HZ   . PHE A 1 38  ? 6.863   14.679  12.791  1     15.689 ? 206 PHE A HZ   1 c 
ATOM   167  N N    . THR A 1 39  ? 11.868  18.371  14.821  1     16.65  ? 207 THR A N    1 ? 
ATOM   168  C CA   . THR A 1 39  ? 12.649  17.883  13.695  1     15.811 ? 207 THR A CA   1 ? 
ATOM   169  C C    . THR A 1 39  ? 13.048  16.435  13.979  1     17.049 ? 207 THR A C    1 ? 
ATOM   170  O O    . THR A 1 39  ? 12.831  15.875  15.055  1     16.605 ? 207 THR A O    1 ? 
ATOM   171  C CB   . THR A 1 39  ? 13.837  18.816  13.393  1     17.166 ? 207 THR A CB   1 ? 
ATOM   172  O OG1  . THR A 1 39  ? 14.416  18.288  12.187  1     16.527 ? 207 THR A OG1  1 ? 
ATOM   173  C CG2  . THR A 1 39  ? 14.85   18.859  14.511  1     17.799 ? 207 THR A CG2  1 ? 
ATOM   174  H H    . THR A 1 39  ? 12.257  18.406  15.647  1     16.539 ? 207 THR A H    1 c 
ATOM   175  H HA   . THR A 1 39  ? 12.072  17.88   12.906  1     16.446 ? 207 THR A HA   1 c 
ATOM   176  H HB   . THR A 1 39  ? 13.5    19.726  13.218  1     16.926 ? 207 THR A HB   1 c 
ATOM   177  H HG21 . THR A 1 39  ? 15.514  19.542  14.319  1     17.605 ? 207 THR A HG21 1 c 
ATOM   178  H HG22 . THR A 1 39  ? 15.29   17.996  14.588  1     17.603 ? 207 THR A HG22 1 c 
ATOM   179  H HG23 . THR A 1 39  ? 14.406  19.071  15.349  1     17.595 ? 207 THR A HG23 1 c 
ATOM   180  N N    . TYR A 1 40  ? 13.514  15.768  12.925  1     19.033 ? 208 TYR A N    1 ? 
ATOM   181  C CA   . TYR A 1 40  ? 13.611  14.331  12.866  1     16.861 ? 208 TYR A CA   1 ? 
ATOM   182  C C    . TYR A 1 40  ? 14.732  14.011  11.881  1     17.37  ? 208 TYR A C    1 ? 
ATOM   183  O O    . TYR A 1 40  ? 14.583  14.237  10.67   1     17.847 ? 208 TYR A O    1 ? 
ATOM   184  C CB   . TYR A 1 40  ? 12.236  13.85   12.409  1     17.494 ? 208 TYR A CB   1 ? 
ATOM   185  C CG   . TYR A 1 40  ? 11.968  12.368  12.273  1     16.83  ? 208 TYR A CG   1 ? 
ATOM   186  C CD1  . TYR A 1 40  ? 12.827  11.387  12.784  1     16.484 ? 208 TYR A CD1  1 ? 
ATOM   187  C CD2  . TYR A 1 40  ? 10.759  11.94   11.704  1     18.359 ? 208 TYR A CD2  1 ? 
ATOM   188  C CE1  . TYR A 1 40  ? 12.521  10.048  12.674  1     17.572 ? 208 TYR A CE1  1 ? 
ATOM   189  C CE2  . TYR A 1 40  ? 10.448  10.594  11.587  1     18.589 ? 208 TYR A CE2  1 ? 
ATOM   190  C CZ   . TYR A 1 40  ? 11.34   9.645   12.066  1     18.689 ? 208 TYR A CZ   1 ? 
ATOM   191  O OH   . TYR A 1 40  ? 11.072  8.288   11.958  1     17.383 ? 208 TYR A OH   1 ? 
ATOM   192  H H    . TYR A 1 40  ? 13.781  16.247  12.194  1     18.01  ? 208 TYR A H    1 c 
ATOM   193  H HA   . TYR A 1 40  ? 13.821  13.963  13.763  1     17.46  ? 208 TYR A HA   1 c 
ATOM   194  H HB2  . TYR A 1 40  ? 11.571  14.217  13.033  1     17.203 ? 208 TYR A HB2  1 c 
ATOM   195  H HB3  . TYR A 1 40  ? 12.05   14.27   11.54   1     17.198 ? 208 TYR A HB3  1 c 
ATOM   196  H HD1  . TYR A 1 40  ? 13.639  11.642  13.192  1     16.856 ? 208 TYR A HD1  1 c 
ATOM   197  H HD2  . TYR A 1 40  ? 10.156  12.582  11.365  1     18.029 ? 208 TYR A HD2  1 c 
ATOM   198  H HE1  . TYR A 1 40  ? 13.124  9.402   12.994  1     17.589 ? 208 TYR A HE1  1 c 
ATOM   199  H HE2  . TYR A 1 40  ? 9.647   10.325  11.171  1     18.521 ? 208 TYR A HE2  1 c 
ATOM   200  N N    . GLN A 1 41  ? 15.87   13.563  12.407  1     17.704 ? 209 GLN A N    1 ? 
ATOM   201  C CA   . GLN A 1 41  ? 17.013  13.245  11.573  1     17.661 ? 209 GLN A CA   1 ? 
ATOM   202  C C    . GLN A 1 41  ? 17.711  12.013  12.121  1     19.135 ? 209 GLN A C    1 ? 
ATOM   203  O O    . GLN A 1 41  ? 18.079  12.015  13.288  1     17.177 ? 209 GLN A O    1 ? 
ATOM   204  C CB   . GLN A 1 41  ? 18.049  14.365  11.488  1     19.457 ? 209 GLN A CB   1 ? 
ATOM   205  C CG   . GLN A 1 41  ? 19.21   14.058  10.555  1     19.518 ? 209 GLN A CG   1 ? 
ATOM   206  C CD   . GLN A 1 41  ? 20.232  15.169  10.377  1     18.158 ? 209 GLN A CD   1 ? 
ATOM   207  O OE1  . GLN A 1 41  ? 21.329  15      9.801   1     22.123 ? 209 GLN A OE1  1 ? 
ATOM   208  N NE2  . GLN A 1 41  ? 19.906  16.327  10.869  1     16.9   ? 209 GLN A NE2  1 ? 
ATOM   209  H H    . GLN A 1 41  ? 15.941  13.457  13.312  1     17.617 ? 209 GLN A H    1 c 
ATOM   210  H HA   . GLN A 1 41  ? 16.692  13.047  10.658  1     18.238 ? 209 GLN A HA   1 c 
ATOM   211  H HB2  . GLN A 1 41  ? 17.597  15.178  11.181  1     19.023 ? 209 GLN A HB2  1 c 
ATOM   212  H HB3  . GLN A 1 41  ? 18.4    14.54   12.386  1     19.061 ? 209 GLN A HB3  1 c 
ATOM   213  H HG2  . GLN A 1 41  ? 19.686  13.267  10.884  1     19.18  ? 209 GLN A HG2  1 c 
ATOM   214  H HG3  . GLN A 1 41  ? 18.852  13.835  9.67    1     19.175 ? 209 GLN A HG3  1 c 
ATOM   215  H HE21 . GLN A 1 41  ? 20.435  16.715  11.464  1     17.334 ? 209 GLN A HE21 1 c 
ATOM   216  H HE22 . GLN A 1 41  ? 19.172  16.741  10.598  1     17.309 ? 209 GLN A HE22 1 c 
ATOM   217  N N    . LEU A 1 42  ? 17.87   10.999  11.245  1     17.938 ? 210 LEU A N    1 ? 
ATOM   218  C CA   . LEU A 1 42  ? 18.356  9.696   11.653  1     16.277 ? 210 LEU A CA   1 ? 
ATOM   219  C C    . LEU A 1 42  ? 19.77   9.426   11.122  1     17.355 ? 210 LEU A C    1 ? 
ATOM   220  O O    . LEU A 1 42  ? 20.385  8.458   11.556  1     19.001 ? 210 LEU A O    1 ? 
ATOM   221  C CB   . LEU A 1 42  ? 17.403  8.597   11.179  1     17.928 ? 210 LEU A CB   1 ? 
ATOM   222  C CG   . LEU A 1 42  ? 16.001  8.645   11.793  1     18.975 ? 210 LEU A CG   1 ? 
ATOM   223  C CD1  . LEU A 1 42  ? 15.272  7.382   11.411  1     18.63  ? 210 LEU A CD1  1 ? 
ATOM   224  C CD2  . LEU A 1 42  ? 15.946  8.843   13.309  1     20.106 ? 210 LEU A CD2  1 ? 
ATOM   225  H H    . LEU A 1 42  ? 17.656  11.128  10.366  1     17.823 ? 210 LEU A H    1 c 
ATOM   226  H HA   . LEU A 1 42  ? 18.398  9.673   12.64   1     17.125 ? 210 LEU A HA   1 c 
ATOM   227  H HB2  . LEU A 1 42  ? 17.318  8.663   10.2    1     17.766 ? 210 LEU A HB2  1 c 
ATOM   228  H HB3  . LEU A 1 42  ? 17.808  7.724   11.392  1     17.773 ? 210 LEU A HB3  1 c 
ATOM   229  H HG   . LEU A 1 42  ? 15.516  9.404   11.377  1     18.914 ? 210 LEU A HG   1 c 
ATOM   230  H HD11 . LEU A 1 42  ? 15.334  7.249   10.45   1     18.728 ? 210 LEU A HD11 1 c 
ATOM   231  H HD12 . LEU A 1 42  ? 14.338  7.456   11.667  1     18.737 ? 210 LEU A HD12 1 c 
ATOM   232  H HD13 . LEU A 1 42  ? 15.674  6.625   11.869  1     18.732 ? 210 LEU A HD13 1 c 
ATOM   233  H HD21 . LEU A 1 42  ? 16.013  9.791   13.515  1     19.754 ? 210 LEU A HD21 1 c 
ATOM   234  H HD22 . LEU A 1 42  ? 16.687  8.37    13.725  1     19.754 ? 210 LEU A HD22 1 c 
ATOM   235  H HD23 . LEU A 1 42  ? 15.108  8.497   13.656  1     19.713 ? 210 LEU A HD23 1 c 
ATOM   236  N N    . THR A 1 43  ? 20.307  10.235  10.201  1     17.318 ? 211 THR A N    1 ? 
ATOM   237  C CA   . THR A 1 43  ? 21.599  9.895   9.613   1     20.456 ? 211 THR A CA   1 ? 
ATOM   238  C C    . THR A 1 43  ? 22.233  11.169  9.07    1     18.881 ? 211 THR A C    1 ? 
ATOM   239  O O    . THR A 1 43  ? 21.582  12.21   9.025   1     18.819 ? 211 THR A O    1 ? 
ATOM   240  C CB   . THR A 1 43  ? 21.36   8.848   8.505   1     23.212 ? 211 THR A CB   1 ? 
ATOM   241  O OG1  . THR A 1 43  ? 22.62   8.301   8.138   1     26.78  ? 211 THR A OG1  1 ? 
ATOM   242  C CG2  . THR A 1 43  ? 20.708  9.43    7.264   1     21.882 ? 211 THR A CG2  1 ? 
ATOM   243  H H    . THR A 1 43  ? 19.879  10.997  9.935   1     17.989 ? 211 THR A H    1 c 
ATOM   244  H HA   . THR A 1 43  ? 22.182  9.513   10.302  1     20.04  ? 211 THR A HA   1 c 
ATOM   245  H HB   . THR A 1 43  ? 20.785  8.124   8.851   1     23.055 ? 211 THR A HB   1 c 
ATOM   246  H HG21 . THR A 1 43  ? 20.258  8.722   6.773   1     22.258 ? 211 THR A HG21 1 c 
ATOM   247  H HG22 . THR A 1 43  ? 21.386  9.833   6.696   1     22.265 ? 211 THR A HG22 1 c 
ATOM   248  H HG23 . THR A 1 43  ? 20.058  10.105  7.521   1     22.222 ? 211 THR A HG23 1 c 
ATOM   249  N N    . ASN A 1 44  ? 23.474  11.055  8.568   1     21.977 ? 212 ASN A N    1 ? 
ATOM   250  C CA   . ASN A 1 44  ? 24.174  12.164  7.929   1     20.103 ? 212 ASN A CA   1 ? 
ATOM   251  C C    . ASN A 1 44  ? 24.335  13.337  8.905   1     19.241 ? 212 ASN A C    1 ? 
ATOM   252  O O    . ASN A 1 44  ? 24.14   14.505  8.55    1     21.094 ? 212 ASN A O    1 ? 
ATOM   253  C CB   . ASN A 1 44  ? 23.471  12.595  6.65    1     21.639 ? 212 ASN A CB   1 ? 
ATOM   254  C CG   . ASN A 1 44  ? 24.289  13.538  5.807   1     26.328 ? 212 ASN A CG   1 ? 
ATOM   255  O OD1  . ASN A 1 44  ? 25.519  13.427  5.744   1     27.595 ? 212 ASN A OD1  1 ? 
ATOM   256  N ND2  . ASN A 1 44  ? 23.613  14.44   5.11    1     30.643 ? 212 ASN A ND2  1 ? 
ATOM   257  H H    . ASN A 1 44  ? 23.901  10.249  8.628   1     20.772 ? 212 ASN A H    1 c 
ATOM   258  H HA   . ASN A 1 44  ? 25.071  11.847  7.681   1     20.631 ? 212 ASN A HA   1 c 
ATOM   259  H HB2  . ASN A 1 44  ? 23.262  11.799  6.121   1     22.264 ? 212 ASN A HB2  1 c 
ATOM   260  H HB3  . ASN A 1 44  ? 22.628  13.03   6.88    1     22.248 ? 212 ASN A HB3  1 c 
ATOM   261  H HD21 . ASN A 1 44  ? 23.944  15.255  5.004   1     29.229 ? 212 ASN A HD21 1 c 
ATOM   262  H HD22 . ASN A 1 44  ? 22.83   14.227  4.752   1     29.183 ? 212 ASN A HD22 1 c 
ATOM   263  N N    . TYR A 1 45  ? 24.634  13.015  10.165  1     19.619 ? 213 TYR A N    1 ? 
ATOM   264  C CA   . TYR A 1 45  ? 24.937  14.034  11.16   1     18.626 ? 213 TYR A CA   1 ? 
ATOM   265  C C    . TYR A 1 45  ? 26.298  14.627  10.778  1     21.489 ? 213 TYR A C    1 ? 
ATOM   266  O O    . TYR A 1 45  ? 27.261  13.875  10.648  1     20.947 ? 213 TYR A O    1 ? 
ATOM   267  C CB   . TYR A 1 45  ? 25.046  13.436  12.561  1     18.919 ? 213 TYR A CB   1 ? 
ATOM   268  C CG   . TYR A 1 45  ? 23.764  12.738  13.011  1     20.754 ? 213 TYR A CG   1 ? 
ATOM   269  C CD1  . TYR A 1 45  ? 22.609  13.468  13.269  1     21.292 ? 213 TYR A CD1  1 ? 
ATOM   270  C CD2  . TYR A 1 45  ? 23.709  11.369  13.139  1     19.833 ? 213 TYR A CD2  1 ? 
ATOM   271  C CE1  . TYR A 1 45  ? 21.425  12.839  13.626  1     23.006 ? 213 TYR A CE1  1 ? 
ATOM   272  C CE2  . TYR A 1 45  ? 22.53   10.728  13.499  1     21.716 ? 213 TYR A CE2  1 ? 
ATOM   273  C CZ   . TYR A 1 45  ? 21.39   11.466  13.771  1     19.466 ? 213 TYR A CZ   1 ? 
ATOM   274  O OH   . TYR A 1 45  ? 20.227  10.828  14.11   1     20.682 ? 213 TYR A OH   1 ? 
ATOM   275  H H    . TYR A 1 45  ? 24.671  12.136  10.411  1     19.327 ? 213 TYR A H    1 c 
ATOM   276  H HA   . TYR A 1 45  ? 24.235  14.728  11.15   1     19.389 ? 213 TYR A HA   1 c 
ATOM   277  H HB2  . TYR A 1 45  ? 25.785  12.788  12.573  1     19.284 ? 213 TYR A HB2  1 c 
ATOM   278  H HB3  . TYR A 1 45  ? 25.258  14.153  13.194  1     19.264 ? 213 TYR A HB3  1 c 
ATOM   279  H HD1  . TYR A 1 45  ? 22.623  14.407  13.173  1     21.514 ? 213 TYR A HD1  1 c 
ATOM   280  H HD2  . TYR A 1 45  ? 24.478  10.855  12.957  1     20.466 ? 213 TYR A HD2  1 c 
ATOM   281  H HE1  . TYR A 1 45  ? 20.653  13.351  13.802  1     21.705 ? 213 TYR A HE1  1 c 
ATOM   282  H HE2  . TYR A 1 45  ? 22.512  9.792   13.587  1     20.745 ? 213 TYR A HE2  1 c 
ATOM   283  N N    . PRO A 1 46  ? 26.425  15.954  10.565  1     20.533 ? 214 PRO A N    1 ? 
ATOM   284  C CA   . PRO A 1 46  ? 27.696  16.516  10.095  1     21.897 ? 214 PRO A CA   1 ? 
ATOM   285  C C    . PRO A 1 46  ? 28.775  16.318  11.164  1     22.314 ? 214 PRO A C    1 ? 
ATOM   286  O O    . PRO A 1 46  ? 28.558  16.627  12.345  1     22.19  ? 214 PRO A O    1 ? 
ATOM   287  C CB   . PRO A 1 46  ? 27.359  18.018  9.853   1     22.098 ? 214 PRO A CB   1 ? 
ATOM   288  C CG   . PRO A 1 46  ? 25.868  18.032  9.716   1     24.149 ? 214 PRO A CG   1 ? 
ATOM   289  C CD   . PRO A 1 46  ? 25.383  16.989  10.742  1     20.64  ? 214 PRO A CD   1 ? 
ATOM   290  H HA   . PRO A 1 46  ? 27.958  16.086  9.244   1     21.729 ? 214 PRO A HA   1 c 
ATOM   291  H HB2  . PRO A 1 46  ? 27.648  18.574  10.615  1     22.508 ? 214 PRO A HB2  1 c 
ATOM   292  H HB3  . PRO A 1 46  ? 27.792  18.349  9.031   1     22.509 ? 214 PRO A HB3  1 c 
ATOM   293  H HG2  . PRO A 1 46  ? 25.505  18.918  9.922   1     22.853 ? 214 PRO A HG2  1 c 
ATOM   294  H HG3  . PRO A 1 46  ? 25.597  17.78   8.808   1     22.853 ? 214 PRO A HG3  1 c 
ATOM   295  H HD2  . PRO A 1 46  ? 25.384  17.353  11.655  1     21.332 ? 214 PRO A HD2  1 c 
ATOM   296  H HD3  . PRO A 1 46  ? 24.489  16.659  10.511  1     21.304 ? 214 PRO A HD3  1 c 
ATOM   297  N N    . GLN A 1 47  ? 29.885  15.694  10.714  1     21.507 ? 215 GLN A N    1 ? 
ATOM   298  C CA   . GLN A 1 47  ? 31.031  15.384  11.541  1     21.372 ? 215 GLN A CA   1 ? 
ATOM   299  C C    . GLN A 1 47  ? 30.603  14.473  12.689  1     22.294 ? 215 GLN A C    1 ? 
ATOM   300  O O    . GLN A 1 47  ? 31.33   14.339  13.662  1     20.909 ? 215 GLN A O    1 ? 
ATOM   301  C CB   . GLN A 1 47  ? 31.742  16.627  12.071  1     23.848 ? 215 GLN A CB   1 ? 
ATOM   302  C CG   . GLN A 1 47  ? 32.379  17.482  10.976  1     25.583 ? 215 GLN A CG   1 ? 
ATOM   303  C CD   . GLN A 1 47  ? 31.343  18.298  10.243  1     26.338 ? 215 GLN A CD   1 ? 
ATOM   304  O OE1  . GLN A 1 47  ? 30.626  19.109  10.838  1     27.13  ? 215 GLN A OE1  1 ? 
ATOM   305  N NE2  . GLN A 1 47  ? 31.228  18.062  8.945   1     26.43  ? 215 GLN A NE2  1 ? 
ATOM   306  H H    . GLN A 1 47  ? 29.92   15.452  9.834   1     21.667 ? 215 GLN A H    1 c 
ATOM   307  H HA   . GLN A 1 47  ? 31.679  14.888  10.982  1     22.006 ? 215 GLN A HA   1 c 
ATOM   308  H HB2  . GLN A 1 47  ? 31.104  17.173  12.574  1     23.648 ? 215 GLN A HB2  1 c 
ATOM   309  H HB3  . GLN A 1 47  ? 32.445  16.347  12.693  1     23.615 ? 215 GLN A HB3  1 c 
ATOM   310  H HG2  . GLN A 1 47  ? 33.04   18.087  11.377  1     25.353 ? 215 GLN A HG2  1 c 
ATOM   311  H HG3  . GLN A 1 47  ? 32.847  16.902  10.339  1     25.363 ? 215 GLN A HG3  1 c 
ATOM   312  H HE21 . GLN A 1 47  ? 31.197  18.74   8.373   1     26.4   ? 215 GLN A HE21 1 c 
ATOM   313  H HE22 . GLN A 1 47  ? 31.183  17.227  8.649   1     26.393 ? 215 GLN A HE22 1 c 
ATOM   314  N N    . GLY A 1 48  ? 29.492  13.772  12.466  1     20.03  ? 216 GLY A N    1 ? 
ATOM   315  C CA   . GLY A 1 48  ? 28.943  12.842  13.44   1     20.535 ? 216 GLY A CA   1 ? 
ATOM   316  C C    . GLY A 1 48  ? 28.367  13.539  14.666  1     19.086 ? 216 GLY A C    1 ? 
ATOM   317  O O    . GLY A 1 48  ? 28.172  12.865  15.665  1     20.139 ? 216 GLY A O    1 ? 
ATOM   318  H H    . GLY A 1 48  ? 29.081  13.825  11.652  1     20.685 ? 216 GLY A H    1 c 
ATOM   319  H HA2  . GLY A 1 48  ? 28.234  12.31   13.006  1     20.083 ? 216 GLY A HA2  1 c 
ATOM   320  H HA3  . GLY A 1 48  ? 29.654  12.22   13.723  1     20.086 ? 216 GLY A HA3  1 c 
ATOM   321  N N    . LYS A 1 49  ? 28.02   14.816  14.544  1     18.725 ? 217 LYS A N    1 ? 
ATOM   322  C CA   . LYS A 1 49  ? 27.621  15.646  15.663  1     19.977 ? 217 LYS A CA   1 ? 
ATOM   323  C C    . LYS A 1 49  ? 26.217  16.209  15.477  1     19.734 ? 217 LYS A C    1 ? 
ATOM   324  O O    . LYS A 1 49  ? 25.719  16.275  14.356  1     20.09  ? 217 LYS A O    1 ? 
ATOM   325  C CB   . LYS A 1 49  ? 28.652  16.744  15.892  1     22.502 ? 217 LYS A CB   1 ? 
ATOM   326  C CG   . LYS A 1 49  ? 29.969  16.184  16.448  1     26.739 ? 217 LYS A CG   1 ? 
ATOM   327  C CD   . LYS A 1 49  ? 31.041  17.191  16.835  1     32.408 ? 217 LYS A CD   1 ? 
ATOM   328  C CE   . LYS A 1 49  ? 31.509  17.959  15.677  1     38.394 ? 217 LYS A CE   1 ? 
ATOM   329  N NZ   . LYS A 1 49  ? 32.661  18.795  16.041  1     45.348 ? 217 LYS A NZ   1 ? 
ATOM   330  H H    . LYS A 1 49  ? 28.003  15.189  13.71   1     19.136 ? 217 LYS A H    1 c 
ATOM   331  H HA   . LYS A 1 49  ? 27.61   15.084  16.478  1     20.153 ? 217 LYS A HA   1 c 
ATOM   332  H HB2  . LYS A 1 49  ? 28.834  17.2    15.044  1     22.943 ? 217 LYS A HB2  1 c 
ATOM   333  H HB3  . LYS A 1 49  ? 28.294  17.403  16.525  1     22.774 ? 217 LYS A HB3  1 c 
ATOM   334  H HG2  . LYS A 1 49  ? 29.757  15.641  17.239  1     26.802 ? 217 LYS A HG2  1 c 
ATOM   335  H HG3  . LYS A 1 49  ? 30.345  15.575  15.777  1     26.776 ? 217 LYS A HG3  1 c 
ATOM   336  H HD2  . LYS A 1 49  ? 30.682  17.809  17.504  1     32.314 ? 217 LYS A HD2  1 c 
ATOM   337  H HD3  . LYS A 1 49  ? 31.801  16.714  17.235  1     32.362 ? 217 LYS A HD3  1 c 
ATOM   338  H HE2  . LYS A 1 49  ? 31.763  17.355  14.956  1     38.332 ? 217 LYS A HE2  1 c 
ATOM   339  H HE3  . LYS A 1 49  ? 30.791  18.533  15.362  1     38.154 ? 217 LYS A HE3  1 c 
ATOM   340  H HZ1  . LYS A 1 49  ? 33.314  18.285  16.408  1     42.922 ? 217 LYS A HZ1  1 c 
ATOM   341  H HZ2  . LYS A 1 49  ? 32.404  19.424  16.64   1     43.043 ? 217 LYS A HZ2  1 c 
ATOM   342  H HZ3  . LYS A 1 49  ? 32.987  19.205  15.301  1     43.043 ? 217 LYS A HZ3  1 c 
ATOM   343  N N    . LEU A 1 50  ? 25.642  16.69   16.59   1     19.665 ? 218 LEU A N    1 ? 
ATOM   344  C CA   . LEU A 1 50  ? 24.267  17.168  16.63   1     20.851 ? 218 LEU A CA   1 ? 
ATOM   345  C C    . LEU A 1 50  ? 24.171  18.697  16.612  1     21.952 ? 218 LEU A C    1 ? 
ATOM   346  O O    . LEU A 1 50  ? 23.082  19.234  16.851  1     19.56  ? 218 LEU A O    1 ? 
ATOM   347  C CB   . LEU A 1 50  ? 23.62   16.593  17.897  1     20.142 ? 218 LEU A CB   1 ? 
ATOM   348  C CG   . LEU A 1 50  ? 23.462  15.078  17.936  1     20.793 ? 218 LEU A CG   1 ? 
ATOM   349  C CD1  . LEU A 1 50  ? 23.01   14.643  19.359  1     22.191 ? 218 LEU A CD1  1 ? 
ATOM   350  C CD2  . LEU A 1 50  ? 22.472  14.628  16.843  1     22.453 ? 218 LEU A CD2  1 ? 
ATOM   351  H H    . LEU A 1 50  ? 26.135  16.724  17.359  1     19.95  ? 218 LEU A H    1 c 
ATOM   352  H HA   . LEU A 1 50  ? 23.788  16.818  15.839  1     20.692 ? 218 LEU A HA   1 c 
ATOM   353  H HB2  . LEU A 1 50  ? 24.158  16.872  18.673  1     20.471 ? 218 LEU A HB2  1 c 
ATOM   354  H HB3  . LEU A 1 50  ? 22.726  16.993  17.988  1     20.538 ? 218 LEU A HB3  1 c 
ATOM   355  H HG   . LEU A 1 50  ? 24.344  14.667  17.749  1     21.187 ? 218 LEU A HG   1 c 
ATOM   356  H HD11 . LEU A 1 50  ? 23.675  14.922  20.011  1     21.777 ? 218 LEU A HD11 1 c 
ATOM   357  H HD12 . LEU A 1 50  ? 22.915  13.676  19.388  1     21.777 ? 218 LEU A HD12 1 c 
ATOM   358  H HD13 . LEU A 1 50  ? 22.157  15.058  19.569  1     21.777 ? 218 LEU A HD13 1 c 
ATOM   359  H HD21 . LEU A 1 50  ? 22.914  14.641  15.977  1     21.945 ? 218 LEU A HD21 1 c 
ATOM   360  H HD22 . LEU A 1 50  ? 21.709  15.229  16.825  1     21.947 ? 218 LEU A HD22 1 c 
ATOM   361  H HD23 . LEU A 1 50  ? 22.166  13.725  17.034  1     21.952 ? 218 LEU A HD23 1 c 
ATOM   362  N N    . ASP A 1 51  ? 25.249  19.392  16.182  1     21.716 ? 219 ASP A N    1 ? 
ATOM   363  C CA   . ASP A 1 51  ? 25.314  20.846  16.331  1     21.743 ? 219 ASP A CA   1 ? 
ATOM   364  C C    . ASP A 1 51  ? 24.231  21.57   15.512  1     22.54  ? 219 ASP A C    1 ? 
ATOM   365  O O    . ASP A 1 51  ? 23.624  22.525  16.001  1     21.551 ? 219 ASP A O    1 ? 
ATOM   366  C CB   . ASP A 1 51  ? 26.693  21.428  16.034  1     22.167 ? 219 ASP A CB   1 ? 
ATOM   367  C CG   . ASP A 1 51  ? 27.826  20.907  16.906  1     24.133 ? 219 ASP A CG   1 ? 
ATOM   368  O OD1  . ASP A 1 51  ? 27.566  20.087  17.793  1     22.972 ? 219 ASP A OD1  1 ? 
ATOM   369  O OD2  . ASP A 1 51  ? 28.983  21.321  16.673  1     24.309 ? 219 ASP A OD2  1 ? 
ATOM   370  H H    . ASP A 1 51  ? 25.944  18.961  15.775  1     21.758 ? 219 ASP A H    1 c 
ATOM   371  H HA   . ASP A 1 51  ? 25.144  21.052  17.277  1     21.965 ? 219 ASP A HA   1 c 
ATOM   372  H HB2  . ASP A 1 51  ? 26.917  21.238  15.099  1     22.505 ? 219 ASP A HB2  1 c 
ATOM   373  H HB3  . ASP A 1 51  ? 26.651  22.402  16.141  1     22.505 ? 219 ASP A HB3  1 c 
ATOM   374  N N    . ALA A 1 52  ? 23.952  21.1    14.293  1     23.243 ? 220 ALA A N    1 ? 
ATOM   375  C CA   . ALA A 1 52  ? 22.925  21.725  13.473  1     22.48  ? 220 ALA A CA   1 ? 
ATOM   376  C C    . ALA A 1 52  ? 21.543  21.511  14.092  1     20.637 ? 220 ALA A C    1 ? 
ATOM   377  O O    . ALA A 1 52  ? 20.7    22.418  14.109  1     19.956 ? 220 ALA A O    1 ? 
ATOM   378  C CB   . ALA A 1 52  ? 22.989  21.196  12.057  1     23.179 ? 220 ALA A CB   1 ? 
ATOM   379  H H    . ALA A 1 52  ? 24.412  20.383  13.961  1     22.887 ? 220 ALA A H    1 c 
ATOM   380  H HA   . ALA A 1 52  ? 23.103  22.706  13.452  1     22.398 ? 220 ALA A HA   1 c 
ATOM   381  H HB1  . ALA A 1 52  ? 23.852  21.411  11.666  1     23.038 ? 220 ALA A HB1  1 c 
ATOM   382  H HB2  . ALA A 1 52  ? 22.871  20.232  12.063  1     22.963 ? 220 ALA A HB2  1 c 
ATOM   383  H HB3  . ALA A 1 52  ? 22.285  21.602  11.524  1     22.981 ? 220 ALA A HB3  1 c 
ATOM   384  N N    . ILE A 1 53  ? 21.319  20.332  14.679  1     22.132 ? 221 ILE A N    1 ? 
ATOM   385  C CA   . ILE A 1 53  ? 20.041  20.063  15.329  1     21.596 ? 221 ILE A CA   1 ? 
ATOM   386  C C    . ILE A 1 53  ? 19.93   20.954  16.567  1     22.037 ? 221 ILE A C    1 ? 
ATOM   387  O O    . ILE A 1 53  ? 18.888  21.568  16.808  1     21.883 ? 221 ILE A O    1 ? 
ATOM   388  C CB   . ILE A 1 53  ? 19.905  18.557  15.606  1     22.713 ? 221 ILE A CB   1 ? 
ATOM   389  C CG1  . ILE A 1 53  ? 19.831  17.77   14.266  1     23.478 ? 221 ILE A CG1  1 ? 
ATOM   390  C CG2  . ILE A 1 53  ? 18.676  18.283  16.473  1     25.184 ? 221 ILE A CG2  1 ? 
ATOM   391  C CD1  . ILE A 1 53  ? 20.086  16.289  14.393  1     24.581 ? 221 ILE A CD1  1 ? 
ATOM   392  H H    . ILE A 1 53  ? 21.962  19.682  14.67   1     21.702 ? 221 ILE A H    1 c 
ATOM   393  H HA   . ILE A 1 53  ? 19.328  20.315  14.71   1     21.965 ? 221 ILE A HA   1 c 
ATOM   394  H HB   . ILE A 1 53  ? 20.7    18.26   16.093  1     23.051 ? 221 ILE A HB   1 c 
ATOM   395  H HG12 . ILE A 1 53  ? 18.942  17.9    13.877  1     23.549 ? 221 ILE A HG12 1 c 
ATOM   396  H HG13 . ILE A 1 53  ? 20.485  18.145  13.642  1     23.524 ? 221 ILE A HG13 1 c 
ATOM   397  H HG21 . ILE A 1 53  ? 18.392  17.362  16.361  1     24.416 ? 221 ILE A HG21 1 c 
ATOM   398  H HG22 . ILE A 1 53  ? 17.951  18.876  16.208  1     24.398 ? 221 ILE A HG22 1 c 
ATOM   399  H HG23 . ILE A 1 53  ? 18.894  18.438  17.407  1     24.411 ? 221 ILE A HG23 1 c 
ATOM   400  H HD11 . ILE A 1 53  ? 20.985  16.147  14.746  1     24.181 ? 221 ILE A HD11 1 c 
ATOM   401  H HD12 . ILE A 1 53  ? 20.013  15.863  13.52   1     24.081 ? 221 ILE A HD12 1 c 
ATOM   402  H HD13 . ILE A 1 53  ? 19.435  15.891  15      1     24.144 ? 221 ILE A HD13 1 c 
ATOM   403  N N    . ALA A 1 54  ? 21.03   21.054  17.33   1     22.46  ? 222 ALA A N    1 ? 
ATOM   404  C CA   . ALA A 1 54  ? 21.043  21.858  18.549  1     20.998 ? 222 ALA A CA   1 ? 
ATOM   405  C C    . ALA A 1 54  ? 20.676  23.309  18.238  1     24.525 ? 222 ALA A C    1 ? 
ATOM   406  O O    . ALA A 1 54  ? 19.935  23.946  19.016  1     26.267 ? 222 ALA A O    1 ? 
ATOM   407  C CB   . ALA A 1 54  ? 22.391  21.804  19.233  1     23.197 ? 222 ALA A CB   1 ? 
ATOM   408  H H    . ALA A 1 54  ? 21.788  20.6    17.096  1     22.028 ? 222 ALA A H    1 c 
ATOM   409  H HA   . ALA A 1 54  ? 20.352  21.491  19.167  1     22.291 ? 222 ALA A HA   1 c 
ATOM   410  H HB1  . ALA A 1 54  ? 22.604  20.884  19.462  1     22.521 ? 222 ALA A HB1  1 c 
ATOM   411  H HB2  . ALA A 1 54  ? 23.074  22.153  18.636  1     22.517 ? 222 ALA A HB2  1 c 
ATOM   412  H HB3  . ALA A 1 54  ? 22.368  22.34   20.043  1     22.521 ? 222 ALA A HB3  1 c 
ATOM   413  N N    . ALA A 1 55  ? 21.206  23.821  17.12   1     21.968 ? 223 ALA A N    1 ? 
ATOM   414  C CA   . ALA A 1 55  ? 21.01   25.21   16.748  1     23.243 ? 223 ALA A CA   1 ? 
ATOM   415  C C    . ALA A 1 55  ? 19.613  25.477  16.198  1     25.621 ? 223 ALA A C    1 ? 
ATOM   416  O O    . ALA A 1 55  ? 19.244  26.641  16.168  1     26.849 ? 223 ALA A O    1 ? 
ATOM   417  C CB   . ALA A 1 55  ? 22.021  25.663  15.736  1     22.789 ? 223 ALA A CB   1 ? 
ATOM   418  H H    . ALA A 1 55  ? 21.716  23.291  16.577  1     22.821 ? 223 ALA A H    1 c 
ATOM   419  H HA   . ALA A 1 55  ? 21.122  25.763  17.57   1     23.339 ? 223 ALA A HA   1 c 
ATOM   420  H HB1  . ALA A 1 55  ? 22.918  25.504  16.076  1     22.93  ? 223 ALA A HB1  1 c 
ATOM   421  H HB2  . ALA A 1 55  ? 21.9    25.168  14.908  1     22.941 ? 223 ALA A HB2  1 c 
ATOM   422  H HB3  . ALA A 1 55  ? 21.907  26.612  15.561  1     22.941 ? 223 ALA A HB3  1 c 
ATOM   423  N N    . SER A 1 56  ? 18.917  24.45   15.68   1     22.33  ? 224 SER A N    1 ? 
ATOM   424  C CA   . SER A 1 56  ? 17.596  24.633  15.088  1     23.608 ? 224 SER A CA   1 ? 
ATOM   425  C C    . SER A 1 56  ? 16.595  25.091  16.151  1     26.588 ? 224 SER A C    1 ? 
ATOM   426  O O    . SER A 1 56  ? 16.844  24.947  17.357  1     25.338 ? 224 SER A O    1 ? 
ATOM   427  C CB   . SER A 1 56  ? 17.139  23.366  14.42   1     22.493 ? 224 SER A CB   1 ? 
ATOM   428  O OG   . SER A 1 56  ? 16.758  22.377  15.385  1     22.213 ? 224 SER A OG   1 ? 
ATOM   429  H H    . SER A 1 56  ? 19.281  23.613  15.683  1     23.342 ? 224 SER A H    1 c 
ATOM   430  H HA   . SER A 1 56  ? 17.662  25.343  14.4    1     23.667 ? 224 SER A HA   1 c 
ATOM   431  H HB2  . SER A 1 56  ? 16.379  23.564  13.84   1     22.65  ? 224 SER A HB2  1 c 
ATOM   432  H HB3  . SER A 1 56  ? 17.861  23.016  13.865  1     22.674 ? 224 SER A HB3  1 c 
ATOM   433  N N    . LYS A 1 57  ? 15.441  25.622  15.727  1     23.497 ? 225 LYS A N    1 ? 
ATOM   434  C CA   . LYS A 1 57  ? 14.525  26.239  16.695  1     23.476 ? 225 LYS A CA   1 ? 
ATOM   435  C C    . LYS A 1 57  ? 13.3    25.394  17.096  1     29.803 ? 225 LYS A C    1 ? 
ATOM   436  O O    . LYS A 1 57  ? 12.385  25.889  17.779  1     32.41  ? 225 LYS A O    1 ? 
ATOM   437  C CB   . LYS A 1 57  ? 14.134  27.62   16.138  1     27.536 ? 225 LYS A CB   1 ? 
ATOM   438  C CG   . LYS A 1 57  ? 15.266  28.653  16.244  1     27.036 ? 225 LYS A CG   1 ? 
ATOM   439  H H    . LYS A 1 57  ? 15.217  25.601  14.841  1     24.211 ? 225 LYS A H    1 c 
ATOM   440  H HA   . LYS A 1 57  ? 15.033  26.413  17.527  1     25.29  ? 225 LYS A HA   1 c 
ATOM   441  H HB2  . LYS A 1 57  ? 13.881  27.527  15.195  1     26.446 ? 225 LYS A HB2  1 c 
ATOM   442  H HB3  . LYS A 1 57  ? 13.355  27.96   16.627  1     26.499 ? 225 LYS A HB3  1 c 
ATOM   443  N N    . PHE A 1 58  ? 13.34   24.098  16.806  1     22.7   ? 226 PHE A N    1 ? 
ATOM   444  C CA   . PHE A 1 58  ? 12.274  23.161  17.076  1     20.128 ? 226 PHE A CA   1 ? 
ATOM   445  C C    . PHE A 1 58  ? 12.192  22.844  18.568  1     18.989 ? 226 PHE A C    1 ? 
ATOM   446  O O    . PHE A 1 58  ? 13.197  22.87   19.279  1     18.791 ? 226 PHE A O    1 ? 
ATOM   447  C CB   . PHE A 1 58  ? 12.567  21.894  16.256  1     20.009 ? 226 PHE A CB   1 ? 
ATOM   448  C CG   . PHE A 1 58  ? 12.507  22.094  14.75   1     17.753 ? 226 PHE A CG   1 ? 
ATOM   449  C CD1  . PHE A 1 58  ? 11.285  22.118  14.095  1     17.232 ? 226 PHE A CD1  1 ? 
ATOM   450  C CD2  . PHE A 1 58  ? 13.672  22.288  14.011  1     19.276 ? 226 PHE A CD2  1 ? 
ATOM   451  C CE1  . PHE A 1 58  ? 11.205  22.32   12.731  1     19.738 ? 226 PHE A CE1  1 ? 
ATOM   452  C CE2  . PHE A 1 58  ? 13.587  22.533  12.654  1     20.36  ? 226 PHE A CE2  1 ? 
ATOM   453  C CZ   . PHE A 1 58  ? 12.367  22.508  12.011  1     20.508 ? 226 PHE A CZ   1 ? 
ATOM   454  H H    . PHE A 1 58  ? 14.102  23.771  16.425  1     23.458 ? 226 PHE A H    1 c 
ATOM   455  H HA   . PHE A 1 58  ? 11.415  23.555  16.773  1     20.365 ? 226 PHE A HA   1 c 
ATOM   456  H HB2  . PHE A 1 58  ? 13.461  21.564  16.497  1     19.519 ? 226 PHE A HB2  1 c 
ATOM   457  H HB3  . PHE A 1 58  ? 11.915  21.203  16.509  1     19.497 ? 226 PHE A HB3  1 c 
ATOM   458  H HD1  . PHE A 1 58  ? 10.494  21.98   14.59   1     17.981 ? 226 PHE A HD1  1 c 
ATOM   459  H HD2  . PHE A 1 58  ? 14.506  22.303  14.445  1     19.226 ? 226 PHE A HD2  1 c 
ATOM   460  H HE1  . PHE A 1 58  ? 10.367  22.321  12.298  1     19.286 ? 226 PHE A HE1  1 c 
ATOM   461  H HE2  . PHE A 1 58  ? 14.378  22.646  12.151  1     20.101 ? 226 PHE A HE2  1 c 
ATOM   462  H HZ   . PHE A 1 58  ? 12.323  22.655  11.08   1     20.236 ? 226 PHE A HZ   1 c 
ATOM   463  N N    . ASP A 1 59  ? 10.983  22.528  19.027  1     20.168 ? 227 ASP A N    1 ? 
ATOM   464  C CA   . ASP A 1 59  ? 10.738  22.162  20.422  1     20.615 ? 227 ASP A CA   1 ? 
ATOM   465  C C    . ASP A 1 59  ? 11.224  20.752  20.765  1     19.62  ? 227 ASP A C    1 ? 
ATOM   466  O O    . ASP A 1 59  ? 11.396  20.406  21.929  1     18.871 ? 227 ASP A O    1 ? 
ATOM   467  C CB   . ASP A 1 59  ? 9.252   22.246  20.728  1     22.418 ? 227 ASP A CB   1 ? 
ATOM   468  C CG   . ASP A 1 59  ? 8.694   23.656  20.724  1     25.54  ? 227 ASP A CG   1 ? 
ATOM   469  O OD1  . ASP A 1 59  ? 9.492   24.595  20.826  1     23.271 ? 227 ASP A OD1  1 ? 
ATOM   470  O OD2  . ASP A 1 59  ? 7.471   23.784  20.608  1     23.732 ? 227 ASP A OD2  1 ? 
ATOM   471  H H    . ASP A 1 59  ? 10.275  22.534  18.449  1     20.017 ? 227 ASP A H    1 c 
ATOM   472  H HA   . ASP A 1 59  ? 11.213  22.802  21      1     20.655 ? 227 ASP A HA   1 c 
ATOM   473  H HB2  . ASP A 1 59  ? 8.751   21.715  20.079  1     22.614 ? 227 ASP A HB2  1 c 
ATOM   474  H HB3  . ASP A 1 59  ? 9.089   21.864  21.616  1     22.64  ? 227 ASP A HB3  1 c 
ATOM   475  N N    . LEU A 1 60  ? 11.391  19.894  19.755  1     17.382 ? 228 LEU A N    1 ? 
ATOM   476  C CA   . LEU A 1 60  ? 11.637  18.49   19.985  1     17.019 ? 228 LEU A CA   1 ? 
ATOM   477  C C    . LEU A 1 60  ? 12.456  17.984  18.807  1     17.879 ? 228 LEU A C    1 ? 
ATOM   478  O O    . LEU A 1 60  ? 12.25   18.428  17.683  1     17.419 ? 228 LEU A O    1 ? 
ATOM   479  C CB   . LEU A 1 60  ? 10.32   17.703  20.142  1     18.127 ? 228 LEU A CB   1 ? 
ATOM   480  C CG   . LEU A 1 60  ? 10.464  16.202  20.439  1     18.743 ? 228 LEU A CG   1 ? 
ATOM   481  C CD1  . LEU A 1 60  ? 9.255   15.674  21.219  1     20.745 ? 228 LEU A CD1  1 ? 
ATOM   482  C CD2  . LEU A 1 60  ? 10.604  15.347  19.182  1     17.144 ? 228 LEU A CD2  1 ? 
ATOM   483  H H    . LEU A 1 60  ? 11.331  20.19   18.893  1     17.845 ? 228 LEU A H    1 c 
ATOM   484  H HA   . LEU A 1 60  ? 12.17   18.397  20.807  1     17.461 ? 228 LEU A HA   1 c 
ATOM   485  H HB2  . LEU A 1 60  ? 9.802   18.117  20.871  1     18.033 ? 228 LEU A HB2  1 c 
ATOM   486  H HB3  . LEU A 1 60  ? 9.8     17.807  19.312  1     18.007 ? 228 LEU A HB3  1 c 
ATOM   487  H HG   . LEU A 1 60  ? 11.274  16.07   20.996  1     18.67  ? 228 LEU A HG   1 c 
ATOM   488  H HD11 . LEU A 1 60  ? 9.169   16.162  22.055  1     20.117 ? 228 LEU A HD11 1 c 
ATOM   489  H HD12 . LEU A 1 60  ? 9.377   14.729  21.409  1     20.114 ? 228 LEU A HD12 1 c 
ATOM   490  H HD13 . LEU A 1 60  ? 8.449   15.796  20.69   1     20.129 ? 228 LEU A HD13 1 c 
ATOM   491  H HD21 . LEU A 1 60  ? 11.419  15.575  18.715  1     17.606 ? 228 LEU A HD21 1 c 
ATOM   492  H HD22 . LEU A 1 60  ? 9.844   15.504  18.598  1     17.588 ? 228 LEU A HD22 1 c 
ATOM   493  H HD23 . LEU A 1 60  ? 10.63   14.408  19.43   1     17.629 ? 228 LEU A HD23 1 c 
ATOM   494  N N    . ALA A 1 61  ? 13.403  17.102  19.096  1     17.018 ? 229 ALA A N    1 ? 
ATOM   495  C CA   . ALA A 1 61  ? 14.171  16.415  18.064  1     17.629 ? 229 ALA A CA   1 ? 
ATOM   496  C C    . ALA A 1 61  ? 14.112  14.916  18.267  1     18.886 ? 229 ALA A C    1 ? 
ATOM   497  O O    . ALA A 1 61  ? 14.225  14.436  19.394  1     16.213 ? 229 ALA A O    1 ? 
ATOM   498  C CB   . ALA A 1 61  ? 15.606  16.882  18.044  1     17.655 ? 229 ALA A CB   1 ? 
ATOM   499  H H    . ALA A 1 61  ? 13.586  16.912  19.971  1     17.355 ? 229 ALA A H    1 c 
ATOM   500  H HA   . ALA A 1 61  ? 13.762  16.623  17.185  1     17.723 ? 229 ALA A HA   1 c 
ATOM   501  H HB1  . ALA A 1 61  ? 15.636  17.838  17.867  1     17.649 ? 229 ALA A HB1  1 c 
ATOM   502  H HB2  . ALA A 1 61  ? 16.021  16.703  18.904  1     17.649 ? 229 ALA A HB2  1 c 
ATOM   503  H HB3  . ALA A 1 61  ? 16.094  16.411  17.348  1     17.654 ? 229 ALA A HB3  1 c 
ATOM   504  N N    . ILE A 1 62  ? 13.958  14.192  17.143  1     17.12  ? 230 ILE A N    1 ? 
ATOM   505  C CA   . ILE A 1 62  ? 14.083  12.755  17.092  1     16.297 ? 230 ILE A CA   1 ? 
ATOM   506  C C    . ILE A 1 62  ? 15.409  12.457  16.394  1     16.555 ? 230 ILE A C    1 ? 
ATOM   507  O O    . ILE A 1 62  ? 15.624  12.849  15.247  1     16.59  ? 230 ILE A O    1 ? 
ATOM   508  C CB   . ILE A 1 62  ? 12.925  12.095  16.341  1     17.602 ? 230 ILE A CB   1 ? 
ATOM   509  C CG1  . ILE A 1 62  ? 11.544  12.482  16.909  1     19.144 ? 230 ILE A CG1  1 ? 
ATOM   510  C CG2  . ILE A 1 62  ? 13.126  10.582  16.283  1     15.563 ? 230 ILE A CG2  1 ? 
ATOM   511  C CD1  . ILE A 1 62  ? 10.36   12.187  15.992  1     18.574 ? 230 ILE A CD1  1 ? 
ATOM   512  H H    . ILE A 1 62  ? 13.762  14.629  16.365  1     17.333 ? 230 ILE A H    1 c 
ATOM   513  H HA   . ILE A 1 62  ? 14.108  12.403  18      1     16.728 ? 230 ILE A HA   1 c 
ATOM   514  H HB   . ILE A 1 62  ? 12.957  12.426  15.422  1     17.21  ? 230 ILE A HB   1 c 
ATOM   515  H HG12 . ILE A 1 62  ? 11.411  12.003  17.752  1     18.653 ? 230 ILE A HG12 1 c 
ATOM   516  H HG13 . ILE A 1 62  ? 11.545  13.44   17.112  1     18.646 ? 230 ILE A HG13 1 c 
ATOM   517  H HG21 . ILE A 1 62  ? 12.266  10.137  16.221  1     16.183 ? 230 ILE A HG21 1 c 
ATOM   518  H HG22 . ILE A 1 62  ? 13.585  10.281  17.086  1     16.154 ? 230 ILE A HG22 1 c 
ATOM   519  H HG23 . ILE A 1 62  ? 13.661  10.354  15.503  1     16.151 ? 230 ILE A HG23 1 c 
ATOM   520  H HD11 . ILE A 1 62  ? 10.478  12.661  15.147  1     18.734 ? 230 ILE A HD11 1 c 
ATOM   521  H HD12 . ILE A 1 62  ? 9.536   12.488  16.419  1     18.734 ? 230 ILE A HD12 1 c 
ATOM   522  H HD13 . ILE A 1 62  ? 10.303  11.229  15.82   1     18.716 ? 230 ILE A HD13 1 c 
ATOM   523  N N    . VAL A 1 63  ? 16.309  11.779  17.086  1     16.079 ? 231 VAL A N    1 ? 
ATOM   524  C CA   . VAL A 1 63  ? 17.581  11.331  16.548  1     16.015 ? 231 VAL A CA   1 ? 
ATOM   525  C C    . VAL A 1 63  ? 17.842  9.888   16.948  1     16.487 ? 231 VAL A C    1 ? 
ATOM   526  O O    . VAL A 1 63  ? 17.208  9.357   17.861  1     15.197 ? 231 VAL A O    1 ? 
ATOM   527  C CB   . VAL A 1 63  ? 18.697  12.268  17.07   1     18.266 ? 231 VAL A CB   1 ? 
ATOM   528  C CG1  . VAL A 1 63  ? 18.46   13.692  16.597  1     19.069 ? 231 VAL A CG1  1 ? 
ATOM   529  C CG2  . VAL A 1 63  ? 18.856  12.23   18.581  1     16.996 ? 231 VAL A CG2  1 ? 
ATOM   530  H H    . VAL A 1 63  ? 16.118  11.57   17.955  1     16.197 ? 231 VAL A H    1 c 
ATOM   531  H HA   . VAL A 1 63  ? 17.553  11.384  15.578  1     16.52  ? 231 VAL A HA   1 c 
ATOM   532  H HB   . VAL A 1 63  ? 19.544  11.958  16.673  1     17.733 ? 231 VAL A HB   1 c 
ATOM   533  H HG11 . VAL A 1 63  ? 17.755  14.098  17.129  1     18.812 ? 231 VAL A HG11 1 c 
ATOM   534  H HG12 . VAL A 1 63  ? 18.194  13.684  15.662  1     18.798 ? 231 VAL A HG12 1 c 
ATOM   535  H HG13 . VAL A 1 63  ? 19.278  14.207  16.696  1     18.848 ? 231 VAL A HG13 1 c 
ATOM   536  H HG21 . VAL A 1 63  ? 19.473  12.928  18.858  1     17.366 ? 231 VAL A HG21 1 c 
ATOM   537  H HG22 . VAL A 1 63  ? 19.208  11.366  18.852  1     17.355 ? 231 VAL A HG22 1 c 
ATOM   538  H HG23 . VAL A 1 63  ? 17.995  12.376  19.007  1     17.346 ? 231 VAL A HG23 1 c 
ATOM   539  N N    . GLU A 1 64  ? 18.754  9.221   16.207  1     16.172 ? 232 GLU A N    1 ? 
ATOM   540  C CA   . GLU A 1 64  ? 19.164  7.886   16.605  1     17.472 ? 232 GLU A CA   1 ? 
ATOM   541  C C    . GLU A 1 64  ? 19.928  7.943   17.921  1     17.36  ? 232 GLU A C    1 ? 
ATOM   542  O O    . GLU A 1 64  ? 20.387  8.999   18.325  1     17.25  ? 232 GLU A O    1 ? 
ATOM   543  C CB   . GLU A 1 64  ? 20.022  7.152   15.571  1     17.685 ? 232 GLU A CB   1 ? 
ATOM   544  C CG   . GLU A 1 64  ? 19.243  6.603   14.376  1     18.282 ? 232 GLU A CG   1 ? 
ATOM   545  C CD   . GLU A 1 64  ? 19.498  5.13    14.088  1     23.111 ? 232 GLU A CD   1 ? 
ATOM   546  O OE1  . GLU A 1 64  ? 19.663  4.349   15.045  1     23.124 ? 232 GLU A OE1  1 ? 
ATOM   547  O OE2  . GLU A 1 64  ? 19.467  4.708   12.914  1     25.832 ? 232 GLU A OE2  1 ? 
ATOM   548  H H    . GLU A 1 64  ? 19.116  9.6     15.459  1     16.527 ? 232 GLU A H    1 c 
ATOM   549  H HA   . GLU A 1 64  ? 18.346  7.345   16.748  1     17.222 ? 232 GLU A HA   1 c 
ATOM   550  H HB2  . GLU A 1 64  ? 20.704  7.771   15.236  1     17.78  ? 232 GLU A HB2  1 c 
ATOM   551  H HB3  . GLU A 1 64  ? 20.485  6.413   16.011  1     17.81  ? 232 GLU A HB3  1 c 
ATOM   552  H HG2  . GLU A 1 64  ? 18.283  6.727   14.532  1     19.127 ? 232 GLU A HG2  1 c 
ATOM   553  H HG3  . GLU A 1 64  ? 19.48   7.12    13.579  1     19.146 ? 232 GLU A HG3  1 c 
ATOM   554  N N    . LEU A 1 65  ? 20.017  6.79    18.607  1     16.585 ? 233 LEU A N    1 ? 
ATOM   555  C CA   . LEU A 1 65  ? 20.902  6.613   19.732  1     16.309 ? 233 LEU A CA   1 ? 
ATOM   556  C C    . LEU A 1 65  ? 22.364  6.813   19.336  1     17.042 ? 233 LEU A C    1 ? 
ATOM   557  O O    . LEU A 1 65  ? 23.173  7.107   20.235  1     16.679 ? 233 LEU A O    1 ? 
ATOM   558  C CB   . LEU A 1 65  ? 20.733  5.221   20.324  1     15.974 ? 233 LEU A CB   1 ? 
ATOM   559  C CG   . LEU A 1 65  ? 19.446  4.927   21.081  1     16.228 ? 233 LEU A CG   1 ? 
ATOM   560  C CD1  . LEU A 1 65  ? 19.36   3.453   21.361  1     17.848 ? 233 LEU A CD1  1 ? 
ATOM   561  C CD2  . LEU A 1 65  ? 19.411  5.707   22.406  1     16.965 ? 233 LEU A CD2  1 ? 
ATOM   562  H H    . LEU A 1 65  ? 19.493  6.086   18.351  1     16.701 ? 233 LEU A H    1 c 
ATOM   563  H HA   . LEU A 1 65  ? 20.669  7.289   20.417  1     16.44  ? 233 LEU A HA   1 c 
ATOM   564  H HB2  . LEU A 1 65  ? 20.814  4.569   19.59   1     16.15  ? 233 LEU A HB2  1 c 
ATOM   565  H HB3  . LEU A 1 65  ? 21.489  5.055   20.932  1     16.133 ? 233 LEU A HB3  1 c 
ATOM   566  H HG   . LEU A 1 65  ? 18.673  5.198   20.522  1     16.606 ? 233 LEU A HG   1 c 
ATOM   567  H HD11 . LEU A 1 65  ? 19.319  2.965   20.521  1     17.338 ? 233 LEU A HD11 1 c 
ATOM   568  H HD12 . LEU A 1 65  ? 18.561  3.267   21.882  1     17.341 ? 233 LEU A HD12 1 c 
ATOM   569  H HD13 . LEU A 1 65  ? 20.145  3.171   21.86   1     17.344 ? 233 LEU A HD13 1 c 
ATOM   570  H HD21 . LEU A 1 65  ? 19.288  6.653   22.223  1     16.746 ? 233 LEU A HD21 1 c 
ATOM   571  H HD22 . LEU A 1 65  ? 20.248  5.577   22.883  1     16.744 ? 233 LEU A HD22 1 c 
ATOM   572  H HD23 . LEU A 1 65  ? 18.675  5.386   22.953  1     16.755 ? 233 LEU A HD23 1 c 
ATOM   573  N N    . VAL A 1 66  ? 22.685  6.64    18.026  1     16.372 ? 234 VAL A N    1 ? 
ATOM   574  C CA   . VAL A 1 66  ? 24.032  6.454   17.526  1     17.403 ? 234 VAL A CA   1 ? 
ATOM   575  C C    . VAL A 1 66  ? 24.294  7.403   16.369  1     17.688 ? 234 VAL A C    1 ? 
ATOM   576  O O    . VAL A 1 66  ? 23.385  7.758   15.623  1     18.242 ? 234 VAL A O    1 ? 
ATOM   577  C CB   . VAL A 1 66  ? 24.264  5.004   17.097  1     17.001 ? 234 VAL A CB   1 ? 
ATOM   578  C CG1  . VAL A 1 66  ? 24.305  4.102   18.332  1     17.336 ? 234 VAL A CG1  1 ? 
ATOM   579  C CG2  . VAL A 1 66  ? 23.194  4.51    16.099  1     18.33  ? 234 VAL A CG2  1 ? 
ATOM   580  H H    . VAL A 1 66  ? 22.012  6.635   17.413  1     16.798 ? 234 VAL A H    1 c 
ATOM   581  H HA   . VAL A 1 66  ? 24.654  6.664   18.243  1     17.158 ? 234 VAL A HA   1 c 
ATOM   582  H HB   . VAL A 1 66  ? 25.144  4.963   16.654  1     17.377 ? 234 VAL A HB   1 c 
ATOM   583  H HG11 . VAL A 1 66  ? 23.5    4.232   18.86   1     17.234 ? 234 VAL A HG11 1 c 
ATOM   584  H HG12 . VAL A 1 66  ? 25.083  4.324   18.871  1     17.233 ? 234 VAL A HG12 1 c 
ATOM   585  H HG13 . VAL A 1 66  ? 24.36   3.175   18.056  1     17.251 ? 234 VAL A HG13 1 c 
ATOM   586  H HG21 . VAL A 1 66  ? 23.434  3.623   15.782  1     17.929 ? 234 VAL A HG21 1 c 
ATOM   587  H HG22 . VAL A 1 66  ? 23.142  5.118   15.343  1     17.93  ? 234 VAL A HG22 1 c 
ATOM   588  H HG23 . VAL A 1 66  ? 22.329  4.469   16.54   1     17.916 ? 234 VAL A HG23 1 c 
ATOM   589  N N    . ARG A 1 67  ? 25.533  7.86    16.272  1     16.782 ? 235 ARG A N    1 ? 
ATOM   590  C CA   . ARG A 1 67  ? 25.892  8.871   15.294  1     17.632 ? 235 ARG A CA   1 ? 
ATOM   591  C C    . ARG A 1 67  ? 26.186  8.285   13.917  1     18.439 ? 235 ARG A C    1 ? 
ATOM   592  O O    . ARG A 1 67  ? 26.339  9.042   12.944  1     20.473 ? 235 ARG A O    1 ? 
ATOM   593  C CB   . ARG A 1 67  ? 27.129  9.619   15.801  1     17.117 ? 235 ARG A CB   1 ? 
ATOM   594  C CG   . ARG A 1 67  ? 28.448  8.859   15.665  1     17.185 ? 235 ARG A CG   1 ? 
ATOM   595  C CD   . ARG A 1 67  ? 29.557  9.599   16.338  1     18.961 ? 235 ARG A CD   1 ? 
ATOM   596  N NE   . ARG A 1 67  ? 29.501  9.587   17.792  1     18.916 ? 235 ARG A NE   1 ? 
ATOM   597  C CZ   . ARG A 1 67  ? 29.278  10.627  18.616  1     16.926 ? 235 ARG A CZ   1 ? 
ATOM   598  N NH1  . ARG A 1 67  ? 28.998  11.82   18.139  1     18.999 ? 235 ARG A NH1  1 ? 
ATOM   599  N NH2  . ARG A 1 67  ? 29.286  10.474  19.902  1     18.914 ? 235 ARG A NH2  1 ? 
ATOM   600  H H    . ARG A 1 67  ? 26.181  7.53    16.825  1     17.188 ? 235 ARG A H    1 c 
ATOM   601  H HA   . ARG A 1 67  ? 25.145  9.515   15.21   1     17.518 ? 235 ARG A HA   1 c 
ATOM   602  H HB2  . ARG A 1 67  ? 27.203  10.462  15.306  1     17.265 ? 235 ARG A HB2  1 c 
ATOM   603  H HB3  . ARG A 1 67  ? 26.991  9.841   16.746  1     17.259 ? 235 ARG A HB3  1 c 
ATOM   604  H HG2  . ARG A 1 67  ? 28.36   7.969   16.071  1     17.565 ? 235 ARG A HG2  1 c 
ATOM   605  H HG3  . ARG A 1 67  ? 28.671  8.747   14.715  1     17.572 ? 235 ARG A HG3  1 c 
ATOM   606  H HD2  . ARG A 1 67  ? 30.406  9.204   16.052  1     18.522 ? 235 ARG A HD2  1 c 
ATOM   607  H HD3  . ARG A 1 67  ? 29.547  10.525  16.022  1     18.511 ? 235 ARG A HD3  1 c 
ATOM   608  H HE   . ARG A 1 67  ? 29.627  8.816   18.177  1     18.44  ? 235 ARG A HE   1 c 
ATOM   609  H HH11 . ARG A 1 67  ? 28.329  11.919  17.57   1     18.339 ? 235 ARG A HH11 1 c 
ATOM   610  H HH12 . ARG A 1 67  ? 29.48   12.518  18.389  1     18.336 ? 235 ARG A HH12 1 c 
ATOM   611  H HH21 . ARG A 1 67  ? 29.024  9.707   20.255  1     18.284 ? 235 ARG A HH21 1 c 
ATOM   612  H HH22 . ARG A 1 67  ? 29.548  11.135  20.423  1     18.298 ? 235 ARG A HH22 1 c 
ATOM   613  N N    . ASP A 1 68  ? 26.249  6.977   13.84   1     18.612 ? 236 ASP A N    1 ? 
ATOM   614  C CA   . ASP A 1 68  ? 26.849  6.277   12.717  1     20.851 ? 236 ASP A CA   1 ? 
ATOM   615  C C    . ASP A 1 68  ? 25.986  5.111   12.247  1     22.58  ? 236 ASP A C    1 ? 
ATOM   616  O O    . ASP A 1 68  ? 26.458  4.259   11.515  1     23.175 ? 236 ASP A O    1 ? 
ATOM   617  C CB   . ASP A 1 68  ? 28.232  5.81    13.107  1     20.492 ? 236 ASP A CB   1 ? 
ATOM   618  C CG   . ASP A 1 68  ? 28.295  4.859   14.294  1     20.48  ? 236 ASP A CG   1 ? 
ATOM   619  O OD1  . ASP A 1 68  ? 27.23   4.521   14.863  1     17.687 ? 236 ASP A OD1  1 ? 
ATOM   620  O OD2  . ASP A 1 68  ? 29.439  4.521   14.669  1     21.219 ? 236 ASP A OD2  1 ? 
ATOM   621  H H    . ASP A 1 68  ? 25.941  6.476   14.539  1     19.075 ? 236 ASP A H    1 c 
ATOM   622  H HA   . ASP A 1 68  ? 26.95   6.906   11.967  1     20.617 ? 236 ASP A HA   1 c 
ATOM   623  H HB2  . ASP A 1 68  ? 28.654  5.371   12.339  1     20.585 ? 236 ASP A HB2  1 c 
ATOM   624  H HB3  . ASP A 1 68  ? 28.769  6.599   13.328  1     20.574 ? 236 ASP A HB3  1 c 
ATOM   625  N N    . GLY A 1 69  ? 24.754  5.034   12.732  1     21.977 ? 237 GLY A N    1 ? 
ATOM   626  C CA   . GLY A 1 69  ? 23.827  3.991   12.331  1     25.171 ? 237 GLY A CA   1 ? 
ATOM   627  C C    . GLY A 1 69  ? 24.164  2.653   12.98   1     25.638 ? 237 GLY A C    1 ? 
ATOM   628  O O    . GLY A 1 69  ? 23.528  1.668   12.673  1     26.171 ? 237 GLY A O    1 ? 
ATOM   629  H H    . GLY A 1 69  ? 24.456  5.667   13.317  1     22.722 ? 237 GLY A H    1 c 
ATOM   630  H HA2  . GLY A 1 69  ? 22.914  4.259   12.587  1     24.464 ? 237 GLY A HA2  1 c 
ATOM   631  H HA3  . GLY A 1 69  ? 23.851  3.897   11.349  1     24.451 ? 237 GLY A HA3  1 c 
ATOM   632  N N    . SER A 1 70  ? 25.199  2.606   13.822  1     20.766 ? 238 SER A N    1 ? 
ATOM   633  C CA   . SER A 1 70  ? 25.693  1.343   14.334  1     22.531 ? 238 SER A CA   1 ? 
ATOM   634  C C    . SER A 1 70  ? 25.927  1.411   15.844  1     22.535 ? 238 SER A C    1 ? 
ATOM   635  O O    . SER A 1 70  ? 24.989  1.246   16.629  1     20.127 ? 238 SER A O    1 ? 
ATOM   636  C CB   . SER A 1 70  ? 26.914  0.923   13.551  1     23.296 ? 238 SER A CB   1 ? 
ATOM   637  O OG   . SER A 1 70  ? 27.247  -0.397  13.944  1     27.834 ? 238 SER A OG   1 ? 
ATOM   638  H H    . SER A 1 70  ? 25.584  3.376   14.123  1     22.263 ? 238 SER A H    1 c 
ATOM   639  H HA   . SER A 1 70  ? 24.994  0.658   14.183  1     22.358 ? 238 SER A HA   1 c 
ATOM   640  H HB2  . SER A 1 70  ? 26.711  0.94    12.597  1     24.11  ? 238 SER A HB2  1 c 
ATOM   641  H HB3  . SER A 1 70  ? 27.651  1.528   13.721  1     24.049 ? 238 SER A HB3  1 c 
ATOM   642  N N    . SER A 1 71  ? 27.17   1.637   16.303  1     19.09  ? 239 SER A N    1 ? 
ATOM   643  C CA   . SER A 1 71  ? 27.424  1.488   17.728  1     21.065 ? 239 SER A CA   1 ? 
ATOM   644  C C    . SER A 1 71  ? 28.051  2.721   18.378  1     19.453 ? 239 SER A C    1 ? 
ATOM   645  O O    . SER A 1 71  ? 28.597  2.61    19.487  1     18.471 ? 239 SER A O    1 ? 
ATOM   646  C CB   . SER A 1 71  ? 28.228  0.281   17.992  1     26.173 ? 239 SER A CB   1 ? 
ATOM   647  O OG   . SER A 1 71  ? 29.434  0.346   17.295  1     25.471 ? 239 SER A OG   1 ? 
ATOM   648  H H    . SER A 1 71  ? 27.85   1.889   15.748  1     20.313 ? 239 SER A H    1 c 
ATOM   649  H HA   . SER A 1 71  ? 26.552  1.352   18.175  1     21.24  ? 239 SER A HA   1 c 
ATOM   650  H HB2  . SER A 1 71  ? 28.4    0.197   18.946  1     24.626 ? 239 SER A HB2  1 c 
ATOM   651  H HB3  . SER A 1 71  ? 27.73   -0.505  17.702  1     24.682 ? 239 SER A HB3  1 c 
ATOM   652  N N    . GLY A 1 72  ? 28.08   3.841   17.637  1     16.964 ? 240 GLY A N    1 ? 
ATOM   653  C CA   . GLY A 1 72  ? 28.683  5.073   18.154  1     17.984 ? 240 GLY A CA   1 ? 
ATOM   654  C C    . GLY A 1 72  ? 27.624  5.893   18.89   1     15.243 ? 240 GLY A C    1 ? 
ATOM   655  O O    . GLY A 1 72  ? 27.113  6.89    18.37   1     15.852 ? 240 GLY A O    1 ? 
ATOM   656  H H    . GLY A 1 72  ? 27.692  3.856   16.811  1     17.823 ? 240 GLY A H    1 c 
ATOM   657  H HA2  . GLY A 1 72  ? 29.425  4.854   18.765  1     17.11  ? 240 GLY A HA2  1 c 
ATOM   658  H HA3  . GLY A 1 72  ? 29.048  5.597   17.403  1     17.099 ? 240 GLY A HA3  1 c 
ATOM   659  N N    . TYR A 1 73  ? 27.348  5.508   20.134  1     16.31  ? 241 TYR A N    1 ? 
ATOM   660  C CA   . TYR A 1 73  ? 26.282  6.133   20.911  1     15.972 ? 241 TYR A CA   1 ? 
ATOM   661  C C    . TYR A 1 73  ? 26.61   7.587   21.203  1     17.748 ? 241 TYR A C    1 ? 
ATOM   662  O O    . TYR A 1 73  ? 27.691  7.905   21.709  1     16.003 ? 241 TYR A O    1 ? 
ATOM   663  C CB   . TYR A 1 73  ? 26.041  5.384   22.241  1     15.863 ? 241 TYR A CB   1 ? 
ATOM   664  C CG   . TYR A 1 73  ? 25.453  4.005   21.992  1     16.983 ? 241 TYR A CG   1 ? 
ATOM   665  C CD1  . TYR A 1 73  ? 24.079  3.863   21.865  1     17.135 ? 241 TYR A CD1  1 ? 
ATOM   666  C CD2  . TYR A 1 73  ? 26.243  2.876   21.8    1     17.8   ? 241 TYR A CD2  1 ? 
ATOM   667  C CE1  . TYR A 1 73  ? 23.5    2.648   21.556  1     18.78  ? 241 TYR A CE1  1 ? 
ATOM   668  C CE2  . TYR A 1 73  ? 25.677  1.636   21.554  1     19.831 ? 241 TYR A CE2  1 ? 
ATOM   669  C CZ   . TYR A 1 73  ? 24.3    1.533   21.405  1     20.104 ? 241 TYR A CZ   1 ? 
ATOM   670  O OH   . TYR A 1 73  ? 23.654  0.369   21.126  1     21.846 ? 241 TYR A OH   1 ? 
ATOM   671  H H    . TYR A 1 73  ? 27.84   4.841   20.517  1     16.008 ? 241 TYR A H    1 c 
ATOM   672  H HA   . TYR A 1 73  ? 25.451  6.094   20.377  1     16.347 ? 241 TYR A HA   1 c 
ATOM   673  H HB2  . TYR A 1 73  ? 26.896  5.293   22.717  1     16.138 ? 241 TYR A HB2  1 c 
ATOM   674  H HB3  . TYR A 1 73  ? 25.421  5.907   22.797  1     16.145 ? 241 TYR A HB3  1 c 
ATOM   675  H HD1  . TYR A 1 73  ? 23.53   4.625   21.947  1     17.49  ? 241 TYR A HD1  1 c 
ATOM   676  H HD2  . TYR A 1 73  ? 27.18   2.946   21.89   1     18.066 ? 241 TYR A HD2  1 c 
ATOM   677  H HE1  . TYR A 1 73  ? 22.563  2.572   21.484  1     18.677 ? 241 TYR A HE1  1 c 
ATOM   678  H HE2  . TYR A 1 73  ? 26.225  0.881   21.427  1     19.37  ? 241 TYR A HE2  1 c 
ATOM   679  N N    . PHE A 1 74  ? 25.617  8.477   20.974  1     16.717 ? 242 PHE A N    1 ? 
ATOM   680  C CA   . PHE A 1 74  ? 25.717  9.834   21.494  1     18.093 ? 242 PHE A CA   1 ? 
ATOM   681  C C    . PHE A 1 74  ? 25.817  9.858   23.022  1     18.036 ? 242 PHE A C    1 ? 
ATOM   682  O O    . PHE A 1 74  ? 25.232  9.03    23.719  1     17.228 ? 242 PHE A O    1 ? 
ATOM   683  C CB   . PHE A 1 74  ? 24.52   10.67   21.086  1     16.149 ? 242 PHE A CB   1 ? 
ATOM   684  C CG   . PHE A 1 74  ? 24.42   10.941  19.598  1     16.614 ? 242 PHE A CG   1 ? 
ATOM   685  C CD1  . PHE A 1 74  ? 25.358  11.755  18.96   1     17.052 ? 242 PHE A CD1  1 ? 
ATOM   686  C CD2  . PHE A 1 74  ? 23.37   10.415  18.851  1     17.81  ? 242 PHE A CD2  1 ? 
ATOM   687  C CE1  . PHE A 1 74  ? 25.231  12.041  17.586  1     17.649 ? 242 PHE A CE1  1 ? 
ATOM   688  C CE2  . PHE A 1 74  ? 23.206  10.76   17.521  1     17.609 ? 242 PHE A CE2  1 ? 
ATOM   689  C CZ   . PHE A 1 74  ? 24.179  11.509  16.871  1     17.632 ? 242 PHE A CZ   1 ? 
ATOM   690  H H    . PHE A 1 74  ? 24.879  8.234   20.492  1     17.233 ? 242 PHE A H    1 c 
ATOM   691  H HA   . PHE A 1 74  ? 26.534  10.25   21.115  1     17.448 ? 242 PHE A HA   1 c 
ATOM   692  H HB2  . PHE A 1 74  ? 23.704  10.209  21.382  1     16.696 ? 242 PHE A HB2  1 c 
ATOM   693  H HB3  . PHE A 1 74  ? 24.565  11.531  21.56   1     16.693 ? 242 PHE A HB3  1 c 
ATOM   694  H HD1  . PHE A 1 74  ? 26.083  12.109  19.45   1     17.091 ? 242 PHE A HD1  1 c 
ATOM   695  H HD2  . PHE A 1 74  ? 22.704  9.907   19.285  1     17.464 ? 242 PHE A HD2  1 c 
ATOM   696  H HE1  . PHE A 1 74  ? 25.876  12.578  17.153  1     17.5   ? 242 PHE A HE1  1 c 
ATOM   697  H HE2  . PHE A 1 74  ? 22.504  10.372  17.023  1     17.648 ? 242 PHE A HE2  1 c 
ATOM   698  H HZ   . PHE A 1 74  ? 24.087  11.706  15.952  1     17.631 ? 242 PHE A HZ   1 c 
ATOM   699  N N    . THR A 1 75  ? 26.646  10.755  23.537  1     18.86  ? 243 THR A N    1 ? 
ATOM   700  C CA   . THR A 1 75  ? 26.945  10.801  24.961  1     18.124 ? 243 THR A CA   1 ? 
ATOM   701  C C    . THR A 1 75  ? 25.92   11.694  25.649  1     17.518 ? 243 THR A C    1 ? 
ATOM   702  O O    . THR A 1 75  ? 25.287  12.501  24.982  1     17.628 ? 243 THR A O    1 ? 
ATOM   703  C CB   . THR A 1 75  ? 28.338  11.349  25.21   1     17.073 ? 243 THR A CB   1 ? 
ATOM   704  O OG1  . THR A 1 75  ? 28.283  12.728  24.849  1     19.12  ? 243 THR A OG1  1 ? 
ATOM   705  C CG2  . THR A 1 75  ? 29.396  10.577  24.455  1     16.231 ? 243 THR A CG2  1 ? 
ATOM   706  H H    . THR A 1 75  ? 27.038  11.372  22.988  1     18.46  ? 243 THR A H    1 c 
ATOM   707  H HA   . THR A 1 75  ? 26.889  9.895   25.334  1     17.947 ? 243 THR A HA   1 c 
ATOM   708  H HB   . THR A 1 75  ? 28.538  11.28   26.174  1     17.48  ? 243 THR A HB   1 c 
ATOM   709  H HG21 . THR A 1 75  ? 30.275  10.816  24.794  1     16.483 ? 243 THR A HG21 1 c 
ATOM   710  H HG22 . THR A 1 75  ? 29.344  10.793  23.509  1     16.492 ? 243 THR A HG22 1 c 
ATOM   711  H HG23 . THR A 1 75  ? 29.252  9.624   24.577  1     16.494 ? 243 THR A HG23 1 c 
ATOM   712  N N    . ALA A 1 76  ? 25.805  11.557  26.965  1     16.131 ? 244 ALA A N    1 ? 
ATOM   713  C CA   . ALA A 1 76  ? 24.967  12.442  27.774  1     18.076 ? 244 ALA A CA   1 ? 
ATOM   714  C C    . ALA A 1 76  ? 25.307  13.9    27.508  1     18.174 ? 244 ALA A C    1 ? 
ATOM   715  O O    . ALA A 1 76  ? 24.399  14.735  27.404  1     18.29  ? 244 ALA A O    1 ? 
ATOM   716  C CB   . ALA A 1 76  ? 25.059  12.083  29.229  1     19.747 ? 244 ALA A CB   1 ? 
ATOM   717  H H    . ALA A 1 76  ? 26.265  10.887  27.383  1     16.912 ? 244 ALA A H    1 c 
ATOM   718  H HA   . ALA A 1 76  ? 24.03   12.303  27.482  1     17.993 ? 244 ALA A HA   1 c 
ATOM   719  H HB1  . ALA A 1 76  ? 24.699  11.191  29.369  1     19.234 ? 244 ALA A HB1  1 c 
ATOM   720  H HB2  . ALA A 1 76  ? 25.989  12.102  29.512  1     19.234 ? 244 ALA A HB2  1 c 
ATOM   721  H HB3  . ALA A 1 76  ? 24.55   12.721  29.756  1     19.239 ? 244 ALA A HB3  1 c 
ATOM   722  N N    . ALA A 1 77  ? 26.608  14.2    27.429  1     19.045 ? 245 ALA A N    1 ? 
ATOM   723  C CA   . ALA A 1 77  ? 27.034  15.557  27.165  1     18.702 ? 245 ALA A CA   1 ? 
ATOM   724  C C    . ALA A 1 77  ? 26.462  16.067  25.835  1     16.795 ? 245 ALA A C    1 ? 
ATOM   725  O O    . ALA A 1 77  ? 26.056  17.216  25.757  1     18.828 ? 245 ALA A O    1 ? 
ATOM   726  C CB   . ALA A 1 77  ? 28.534  15.693  27.183  1     19.169 ? 245 ALA A CB   1 ? 
ATOM   727  H H    . ALA A 1 77  ? 27.24   13.551  27.554  1     18.735 ? 245 ALA A H    1 c 
ATOM   728  H HA   . ALA A 1 77  ? 26.661  16.132  27.889  1     18.486 ? 245 ALA A HA   1 c 
ATOM   729  H HB1  . ALA A 1 77  ? 28.876  15.434  28.056  1     19.028 ? 245 ALA A HB1  1 c 
ATOM   730  H HB2  . ALA A 1 77  ? 28.923  15.118  26.503  1     19.028 ? 245 ALA A HB2  1 c 
ATOM   731  H HB3  . ALA A 1 77  ? 28.781  16.616  27.003  1     19.028 ? 245 ALA A HB3  1 c 
ATOM   732  N N    . GLU A 1 78  ? 26.457  15.234  24.786  1     14.812 ? 246 GLU A N    1 ? 
ATOM   733  C CA   . GLU A 1 78  ? 25.956  15.67   23.498  1     16.105 ? 246 GLU A CA   1 ? 
ATOM   734  C C    . GLU A 1 78  ? 24.443  15.882  23.548  1     16.346 ? 246 GLU A C    1 ? 
ATOM   735  O O    . GLU A 1 78  ? 23.912  16.845  22.989  1     16.801 ? 246 GLU A O    1 ? 
ATOM   736  C CB   . GLU A 1 78  ? 26.356  14.643  22.44   1     15.971 ? 246 GLU A CB   1 ? 
ATOM   737  C CG   . GLU A 1 78  ? 27.856  14.629  22.131  1     18.787 ? 246 GLU A CG   1 ? 
ATOM   738  C CD   . GLU A 1 78  ? 28.161  13.554  21.082  1     20.887 ? 246 GLU A CD   1 ? 
ATOM   739  O OE1  . GLU A 1 78  ? 28.085  12.365  21.486  1     18.643 ? 246 GLU A OE1  1 ? 
ATOM   740  O OE2  . GLU A 1 78  ? 28.487  13.876  19.914  1     19.031 ? 246 GLU A OE2  1 ? 
ATOM   741  H H    . GLU A 1 78  ? 26.781  14.385  24.875  1     15.612 ? 246 GLU A H    1 c 
ATOM   742  H HA   . GLU A 1 78  ? 26.387  16.533  23.271  1     15.903 ? 246 GLU A HA   1 c 
ATOM   743  H HB2  . GLU A 1 78  ? 26.084  13.752  22.743  1     16.6   ? 246 GLU A HB2  1 c 
ATOM   744  H HB3  . GLU A 1 78  ? 25.869  14.837  21.612  1     16.602 ? 246 GLU A HB3  1 c 
ATOM   745  H HG2  . GLU A 1 78  ? 28.131  15.504  21.784  1     18.551 ? 246 GLU A HG2  1 c 
ATOM   746  H HG3  . GLU A 1 78  ? 28.364  14.44   22.947  1     18.554 ? 246 GLU A HG3  1 c 
ATOM   747  N N    . ILE A 1 79  ? 23.741  14.974  24.21   1     15.499 ? 247 ILE A N    1 ? 
ATOM   748  C CA   . ILE A 1 79  ? 22.297  15.129  24.333  1     17.313 ? 247 ILE A CA   1 ? 
ATOM   749  C C    . ILE A 1 79  ? 21.945  16.322  25.222  1     17.98  ? 247 ILE A C    1 ? 
ATOM   750  O O    . ILE A 1 79  ? 20.999  17.065  24.892  1     18.588 ? 247 ILE A O    1 ? 
ATOM   751  C CB   . ILE A 1 79  ? 21.671  13.802  24.786  1     18.211 ? 247 ILE A CB   1 ? 
ATOM   752  C CG1  . ILE A 1 79  ? 21.978  12.694  23.758  1     17.883 ? 247 ILE A CG1  1 ? 
ATOM   753  C CG2  . ILE A 1 79  ? 20.17   13.972  25.049  1     18.692 ? 247 ILE A CG2  1 ? 
ATOM   754  C CD1  . ILE A 1 79  ? 21.536  13.009  22.332  1     17.699 ? 247 ILE A CD1  1 ? 
ATOM   755  H H    . ILE A 1 79  ? 24.154  14.257  24.599  1     16.118 ? 247 ILE A H    1 c 
ATOM   756  H HA   . ILE A 1 79  ? 21.947  15.324  23.444  1     17.231 ? 247 ILE A HA   1 c 
ATOM   757  H HB   . ILE A 1 79  ? 22.097  13.551  25.627  1     18.063 ? 247 ILE A HB   1 c 
ATOM   758  H HG12 . ILE A 1 79  ? 22.94   12.52   23.756  1     17.886 ? 247 ILE A HG12 1 c 
ATOM   759  H HG13 . ILE A 1 79  ? 21.53   11.872  24.046  1     17.912 ? 247 ILE A HG13 1 c 
ATOM   760  H HG21 . ILE A 1 79  ? 19.726  13.11   24.972  1     18.539 ? 247 ILE A HG21 1 c 
ATOM   761  H HG22 . ILE A 1 79  ? 19.791  14.587  24.398  1     18.537 ? 247 ILE A HG22 1 c 
ATOM   762  H HG23 . ILE A 1 79  ? 20.032  14.324  25.944  1     18.543 ? 247 ILE A HG23 1 c 
ATOM   763  H HD11 . ILE A 1 79  ? 20.668  13.454  22.34   1     17.759 ? 247 ILE A HD11 1 c 
ATOM   764  H HD12 . ILE A 1 79  ? 21.469  12.178  21.824  1     17.753 ? 247 ILE A HD12 1 c 
ATOM   765  H HD13 . ILE A 1 79  ? 22.195  13.591  21.908  1     17.765 ? 247 ILE A HD13 1 c 
ATOM   766  N N    . SER A 1 80  ? 22.737  16.557  26.283  1     19.564 ? 248 SER A N    1 ? 
ATOM   767  C CA   . SER A 1 80  ? 22.508  17.692  27.166  1     19.133 ? 248 SER A CA   1 ? 
ATOM   768  C C    . SER A 1 80  ? 22.594  18.993  26.366  1     21.318 ? 248 SER A C    1 ? 
ATOM   769  O O    . SER A 1 80  ? 21.834  19.919  26.618  1     20.375 ? 248 SER A O    1 ? 
ATOM   770  C CB   . SER A 1 80  ? 23.455  17.696  28.359  1     20.846 ? 248 SER A CB   1 ? 
ATOM   771  O OG   . SER A 1 80  ? 23.117  16.654  29.263  1     25.646 ? 248 SER A OG   1 ? 
ATOM   772  H H    . SER A 1 80  ? 23.429  15.99   26.467  1     19.05  ? 248 SER A H    1 c 
ATOM   773  H HA   . SER A 1 80  ? 21.583  17.615  27.514  1     19.913 ? 248 SER A HA   1 c 
ATOM   774  H HB2  . SER A 1 80  ? 24.372  17.573  28.047  1     21.49  ? 248 SER A HB2  1 c 
ATOM   775  H HB3  . SER A 1 80  ? 23.399  18.556  28.817  1     21.49  ? 248 SER A HB3  1 c 
ATOM   776  N N    . ALA A 1 81  ? 23.524  19.05   25.409  1     19.846 ? 249 ALA A N    1 ? 
ATOM   777  C CA   . ALA A 1 81  ? 23.708  20.23   24.587  1     21.69  ? 249 ALA A CA   1 ? 
ATOM   778  C C    . ALA A 1 81  ? 22.415  20.572  23.814  1     24.534 ? 249 ALA A C    1 ? 
ATOM   779  O O    . ALA A 1 81  ? 22.065  21.752  23.703  1     23.771 ? 249 ALA A O    1 ? 
ATOM   780  C CB   . ALA A 1 81  ? 24.932  20.051  23.735  1     25.681 ? 249 ALA A CB   1 ? 
ATOM   781  H H    . ALA A 1 81  ? 24.073  18.333  25.272  1     20.624 ? 249 ALA A H    1 c 
ATOM   782  H HA   . ALA A 1 81  ? 23.882  20.991  25.208  1     22.56  ? 249 ALA A HA   1 c 
ATOM   783  H HB1  . ALA A 1 81  ? 25.679  19.77   24.289  1     24.378 ? 249 ALA A HB1  1 c 
ATOM   784  H HB2  . ALA A 1 81  ? 24.763  19.376  23.057  1     24.361 ? 249 ALA A HB2  1 c 
ATOM   785  H HB3  . ALA A 1 81  ? 25.153  20.892  23.301  1     24.399 ? 249 ALA A HB3  1 c 
ATOM   786  N N    . LEU A 1 82  ? 21.633  19.571  23.351  1     23.159 ? 250 LEU A N    1 ? 
ATOM   787  C CA   . LEU A 1 82  ? 20.336  19.852  22.712  1     23.411 ? 250 LEU A CA   1 ? 
ATOM   788  C C    . LEU A 1 82  ? 19.318  20.328  23.731  1     23.414 ? 250 LEU A C    1 ? 
ATOM   789  O O    . LEU A 1 82  ? 18.543  21.257  23.492  1     24.455 ? 250 LEU A O    1 ? 
ATOM   790  C CB   . LEU A 1 82  ? 19.758  18.635  22.004  1     24.159 ? 250 LEU A CB   1 ? 
ATOM   791  C CG   . LEU A 1 82  ? 20.317  18.305  20.631  1     28.694 ? 250 LEU A CG   1 ? 
ATOM   792  C CD1  . LEU A 1 82  ? 21.818  18.076  20.701  1     33.49  ? 250 LEU A CD1  1 ? 
ATOM   793  C CD2  . LEU A 1 82  ? 19.623  17.085  20.094  1     25.508 ? 250 LEU A CD2  1 ? 
ATOM   794  H H    . LEU A 1 82  ? 21.906  18.703  23.44   1     23.626 ? 250 LEU A H    1 c 
ATOM   795  H HA   . LEU A 1 82  ? 20.471  20.574  22.046  1     23.504 ? 250 LEU A HA   1 c 
ATOM   796  H HB2  . LEU A 1 82  ? 19.888  17.851  22.586  1     24.904 ? 250 LEU A HB2  1 c 
ATOM   797  H HB3  . LEU A 1 82  ? 18.785  18.765  21.913  1     24.935 ? 250 LEU A HB3  1 c 
ATOM   798  H HG   . LEU A 1 82  ? 20.137  19.068  20.024  1     27.976 ? 250 LEU A HG   1 c 
ATOM   799  H HD11 . LEU A 1 82  ? 22.274  18.926  20.823  1     31.766 ? 250 LEU A HD11 1 c 
ATOM   800  H HD12 . LEU A 1 82  ? 22.12   17.666  19.88   1     31.625 ? 250 LEU A HD12 1 c 
ATOM   801  H HD13 . LEU A 1 82  ? 22.021  17.489  21.446  1     31.652 ? 250 LEU A HD13 1 c 
ATOM   802  H HD21 . LEU A 1 82  ? 18.666  17.251  20.044  1     26.428 ? 250 LEU A HD21 1 c 
ATOM   803  H HD22 . LEU A 1 82  ? 19.788  16.33   20.685  1     26.428 ? 250 LEU A HD22 1 c 
ATOM   804  H HD23 . LEU A 1 82  ? 19.963  16.881  19.207  1     26.452 ? 250 LEU A HD23 1 c 
ATOM   805  N N    . LYS A 1 83  ? 19.281  19.659  24.885  1     19.585 ? 251 LYS A N    1 ? 
ATOM   806  C CA   . LYS A 1 83  ? 18.287  19.968  25.879  1     21.873 ? 251 LYS A CA   1 ? 
ATOM   807  C C    . LYS A 1 83  ? 18.505  21.376  26.426  1     24.956 ? 251 LYS A C    1 ? 
ATOM   808  O O    . LYS A 1 83  ? 17.55   22.022  26.826  1     24.764 ? 251 LYS A O    1 ? 
ATOM   809  C CB   . LYS A 1 83  ? 18.31   18.917  26.999  1     23.116 ? 251 LYS A CB   1 ? 
ATOM   810  C CG   . LYS A 1 83  ? 17.907  17.519  26.536  1     22.839 ? 251 LYS A CG   1 ? 
ATOM   811  C CD   . LYS A 1 83  ? 17.679  16.509  27.651  1     22.707 ? 251 LYS A CD   1 ? 
ATOM   812  C CE   . LYS A 1 83  ? 18.86   16.359  28.556  1     26.391 ? 251 LYS A CE   1 ? 
ATOM   813  N NZ   . LYS A 1 83  ? 18.581  15.338  29.572  1     24.866 ? 251 LYS A NZ   1 ? 
ATOM   814  H H    . LYS A 1 83  ? 19.884  18.992  25.051  1     21.02  ? 251 LYS A H    1 c 
ATOM   815  H HA   . LYS A 1 83  ? 17.4    19.938  25.448  1     22.18  ? 251 LYS A HA   1 c 
ATOM   816  H HB2  . LYS A 1 83  ? 19.216  18.876  27.373  1     22.797 ? 251 LYS A HB2  1 c 
ATOM   817  H HB3  . LYS A 1 83  ? 17.701  19.199  27.714  1     22.772 ? 251 LYS A HB3  1 c 
ATOM   818  H HG2  . LYS A 1 83  ? 17.084  17.595  26.007  1     22.925 ? 251 LYS A HG2  1 c 
ATOM   819  H HG3  . LYS A 1 83  ? 18.608  17.177  25.941  1     22.845 ? 251 LYS A HG3  1 c 
ATOM   820  H HD2  . LYS A 1 83  ? 16.903  16.791  28.182  1     23.606 ? 251 LYS A HD2  1 c 
ATOM   821  H HD3  . LYS A 1 83  ? 17.47   15.636  27.251  1     23.566 ? 251 LYS A HD3  1 c 
ATOM   822  H HE2  . LYS A 1 83  ? 19.643  16.095  28.041  1     25.141 ? 251 LYS A HE2  1 c 
ATOM   823  H HE3  . LYS A 1 83  ? 19.054  17.201  29.005  1     25.122 ? 251 LYS A HE3  1 c 
ATOM   824  H HZ1  . LYS A 1 83  ? 18.364  14.556  29.172  1     25.251 ? 251 LYS A HZ1  1 c 
ATOM   825  H HZ2  . LYS A 1 83  ? 17.891  15.606  30.093  1     25.308 ? 251 LYS A HZ2  1 c 
ATOM   826  H HZ3  . LYS A 1 83  ? 19.314  15.213  30.09   1     25.308 ? 251 LYS A HZ3  1 c 
ATOM   827  N N    . ALA A 1 84  ? 19.756  21.832  26.466  1     26.701 ? 252 ALA A N    1 ? 
ATOM   828  C CA   . ALA A 1 84  ? 20.068  23.121  27.085  1     28.779 ? 252 ALA A CA   1 ? 
ATOM   829  C C    . ALA A 1 84  ? 19.524  24.256  26.221  1     27.459 ? 252 ALA A C    1 ? 
ATOM   830  O O    . ALA A 1 84  ? 19.297  25.345  26.711  1     27.944 ? 252 ALA A O    1 ? 
ATOM   831  C CB   . ALA A 1 84  ? 21.559  23.257  27.24   1     30.995 ? 252 ALA A CB   1 ? 
ATOM   832  H H    . ALA A 1 84  ? 20.439  21.332  26.123  1     26.629 ? 252 ALA A H    1 c 
ATOM   833  H HA   . ALA A 1 84  ? 19.633  23.162  27.982  1     28.472 ? 252 ALA A HA   1 c 
ATOM   834  H HB1  . ALA A 1 84  ? 21.897  22.537  27.798  1     30.318 ? 252 ALA A HB1  1 c 
ATOM   835  H HB2  . ALA A 1 84  ? 21.984  23.213  26.366  1     30.318 ? 252 ALA A HB2  1 c 
ATOM   836  H HB3  . ALA A 1 84  ? 21.768  24.11   27.656  1     30.318 ? 252 ALA A HB3  1 c 
ATOM   837  N N    . ARG A 1 85  ? 19.323  23.967  24.935  1     28.682 ? 253 ARG A N    1 ? 
ATOM   838  C CA   . ARG A 1 85  ? 18.697  24.872  23.991  1     31.264 ? 253 ARG A CA   1 ? 
ATOM   839  C C    . ARG A 1 85  ? 17.176  24.745  24.075  1     33.865 ? 253 ARG A C    1 ? 
ATOM   840  O O    . ARG A 1 85  ? 16.479  25.344  23.272  1     44.62  ? 253 ARG A O    1 ? 
ATOM   841  C CB   . ARG A 1 85  ? 19.226  24.554  22.586  1     33.532 ? 253 ARG A CB   1 ? 
ATOM   842  C CG   . ARG A 1 85  ? 20.729  24.712  22.338  1     38.226 ? 253 ARG A CG   1 ? 
ATOM   843  H H    . ARG A 1 85  ? 19.616  23.162  24.618  1     29.008 ? 253 ARG A H    1 c 
ATOM   844  H HA   . ARG A 1 85  ? 18.953  25.801  24.223  1     31.574 ? 253 ARG A HA   1 c 
ATOM   845  H HB2  . ARG A 1 85  ? 18.979  23.629  22.374  1     33.919 ? 253 ARG A HB2  1 c 
ATOM   846  H HB3  . ARG A 1 85  ? 18.753  25.131  21.95   1     34.036 ? 253 ARG A HB3  1 c 
ATOM   847  N N    . GLY A 1 86  ? 16.656  23.955  25.023  1     29.87  ? 254 GLY A N    1 ? 
ATOM   848  C CA   . GLY A 1 86  ? 15.229  23.908  25.321  1     27.517 ? 254 GLY A CA   1 ? 
ATOM   849  C C    . GLY A 1 86  ? 14.481  22.726  24.694  1     28.211 ? 254 GLY A C    1 ? 
ATOM   850  O O    . GLY A 1 86  ? 13.296  22.549  24.99   1     31.413 ? 254 GLY A O    1 ? 
ATOM   851  H H    . GLY A 1 86  ? 17.204  23.4    25.493  1     30.145 ? 254 GLY A H    1 c 
ATOM   852  H HA2  . GLY A 1 86  ? 15.122  23.867  26.298  1     28.294 ? 254 GLY A HA2  1 c 
ATOM   853  H HA3  . GLY A 1 86  ? 14.812  24.747  25.017  1     28.335 ? 254 GLY A HA3  1 c 
ATOM   854  N N    . LYS A 1 87  ? 15.15   21.929  23.843  1     23.153 ? 255 LYS A N    1 ? 
ATOM   855  C CA   . LYS A 1 87  ? 14.484  20.846  23.133  1     24.13  ? 255 LYS A CA   1 ? 
ATOM   856  C C    . LYS A 1 87  ? 14.261  19.635  24.031  1     21.756 ? 255 LYS A C    1 ? 
ATOM   857  O O    . LYS A 1 87  ? 15.157  19.255  24.795  1     23.76  ? 255 LYS A O    1 ? 
ATOM   858  C CB   . LYS A 1 87  ? 15.328  20.295  21.978  1     24.208 ? 255 LYS A CB   1 ? 
ATOM   859  C CG   . LYS A 1 87  ? 15.663  21.286  20.953  1     28.087 ? 255 LYS A CG   1 ? 
ATOM   860  C CD   . LYS A 1 87  ? 16.293  20.685  19.72   1     30.202 ? 255 LYS A CD   1 ? 
ATOM   861  C CE   . LYS A 1 87  ? 16.305  21.714  18.637  1     31.527 ? 255 LYS A CE   1 ? 
ATOM   862  N NZ   . LYS A 1 87  ? 16.919  22.952  19.122  1     34.576 ? 255 LYS A NZ   1 ? 
ATOM   863  H H    . LYS A 1 87  ? 16.044  22.057  23.707  1     24.629 ? 255 LYS A H    1 c 
ATOM   864  H HA   . LYS A 1 87  ? 13.619  21.176  22.789  1     23.488 ? 255 LYS A HA   1 c 
ATOM   865  H HB2  . LYS A 1 87  ? 16.164  19.93   22.34   1     25.051 ? 255 LYS A HB2  1 c 
ATOM   866  H HB3  . LYS A 1 87  ? 14.84   19.559  21.551  1     25.095 ? 255 LYS A HB3  1 c 
ATOM   867  H HG2  . LYS A 1 87  ? 14.845  21.761  20.7    1     27.527 ? 255 LYS A HG2  1 c 
ATOM   868  H HG3  . LYS A 1 87  ? 16.281  21.938  21.347  1     27.613 ? 255 LYS A HG3  1 c 
ATOM   869  H HD2  . LYS A 1 87  ? 17.213  20.404  19.917  1     29.997 ? 255 LYS A HD2  1 c 
ATOM   870  H HD3  . LYS A 1 87  ? 15.775  19.905  19.424  1     29.969 ? 255 LYS A HD3  1 c 
ATOM   871  H HE2  . LYS A 1 87  ? 16.8    21.378  17.873  1     31.745 ? 255 LYS A HE2  1 c 
ATOM   872  H HE3  . LYS A 1 87  ? 15.395  21.9    18.347  1     31.784 ? 255 LYS A HE3  1 c 
ATOM   873  H HZ1  . LYS A 1 87  ? 17.616  22.776  19.676  1     33.482 ? 255 LYS A HZ1  1 c 
ATOM   874  H HZ2  . LYS A 1 87  ? 16.308  23.468  19.548  1     33.499 ? 255 LYS A HZ2  1 c 
ATOM   875  H HZ3  . LYS A 1 87  ? 17.237  23.416  18.413  1     33.53  ? 255 LYS A HZ3  1 c 
ATOM   876  N N    . GLN A 1 88  ? 13.104  18.988  23.843  1     20.269 ? 256 GLN A N    1 ? 
ATOM   877  C CA   . GLN A 1 88  ? 12.907  17.603  24.209  1     18.753 ? 256 GLN A CA   1 ? 
ATOM   878  C C    . GLN A 1 88  ? 13.63   16.75   23.175  1     19.354 ? 256 GLN A C    1 ? 
ATOM   879  O O    . GLN A 1 88  ? 13.679  17.107  22.025  1     17.909 ? 256 GLN A O    1 ? 
ATOM   880  C CB   . GLN A 1 88  ? 11.427  17.228  24.112  1     19.608 ? 256 GLN A CB   1 ? 
ATOM   881  C CG   . GLN A 1 88  ? 10.575  17.965  25.138  1     21.993 ? 256 GLN A CG   1 ? 
ATOM   882  C CD   . GLN A 1 88  ? 10.526  17.278  26.479  1     22.693 ? 256 GLN A CD   1 ? 
ATOM   883  O OE1  . GLN A 1 88  ? 10.729  16.067  26.607  1     21.39  ? 256 GLN A OE1  1 ? 
ATOM   884  N NE2  . GLN A 1 88  ? 10.236  18.066  27.511  1     23.057 ? 256 GLN A NE2  1 ? 
ATOM   885  H H    . GLN A 1 88  ? 12.403  19.441  23.469  1     20.311 ? 256 GLN A H    1 c 
ATOM   886  H HA   . GLN A 1 88  ? 13.268  17.438  25.11   1     19.439 ? 256 GLN A HA   1 c 
ATOM   887  H HB2  . GLN A 1 88  ? 11.103  17.446  23.213  1     19.928 ? 256 GLN A HB2  1 c 
ATOM   888  H HB3  . GLN A 1 88  ? 11.33   16.261  24.238  1     19.943 ? 256 GLN A HB3  1 c 
ATOM   889  H HG2  . GLN A 1 88  ? 10.927  18.872  25.263  1     21.561 ? 256 GLN A HG2  1 c 
ATOM   890  H HG3  . GLN A 1 88  ? 9.66    18.047  24.795  1     21.579 ? 256 GLN A HG3  1 c 
ATOM   891  H HE21 . GLN A 1 88  ? 10.635  17.936  28.293  1     22.943 ? 256 GLN A HE21 1 c 
ATOM   892  H HE22 . GLN A 1 88  ? 9.644   18.72   27.417  1     22.937 ? 256 GLN A HE22 1 c 
ATOM   893  N N    . VAL A 1 89  ? 14.211  15.622  23.575  1     15.449 ? 257 VAL A N    1 ? 
ATOM   894  C CA   . VAL A 1 89  ? 14.921  14.802  22.605  1     14.705 ? 257 VAL A CA   1 ? 
ATOM   895  C C    . VAL A 1 89  ? 14.442  13.39   22.77   1     15.258 ? 257 VAL A C    1 ? 
ATOM   896  O O    . VAL A 1 89  ? 14.561  12.837  23.896  1     16.783 ? 257 VAL A O    1 ? 
ATOM   897  C CB   . VAL A 1 89  ? 16.461  14.901  22.752  1     17.536 ? 257 VAL A CB   1 ? 
ATOM   898  C CG1  . VAL A 1 89  ? 17.18   14.177  21.619  1     17.585 ? 257 VAL A CG1  1 ? 
ATOM   899  C CG2  . VAL A 1 89  ? 16.966  16.305  22.833  1     17.88  ? 257 VAL A CG2  1 ? 
ATOM   900  H H    . VAL A 1 89  ? 14.175  15.361  24.449  1     16.194 ? 257 VAL A H    1 c 
ATOM   901  H HA   . VAL A 1 89  ? 14.685  15.104  21.712  1     15.489 ? 257 VAL A HA   1 c 
ATOM   902  H HB   . VAL A 1 89  ? 16.701  14.45   23.595  1     17.039 ? 257 VAL A HB   1 c 
ATOM   903  H HG11 . VAL A 1 89  ? 16.896  14.547  20.766  1     17.562 ? 257 VAL A HG11 1 c 
ATOM   904  H HG12 . VAL A 1 89  ? 16.967  13.231  21.647  1     17.532 ? 257 VAL A HG12 1 c 
ATOM   905  H HG13 . VAL A 1 89  ? 18.14   14.293  21.716  1     17.564 ? 257 VAL A HG13 1 c 
ATOM   906  H HG21 . VAL A 1 89  ? 17.938  16.302  22.845  1     17.77  ? 257 VAL A HG21 1 c 
ATOM   907  H HG22 . VAL A 1 89  ? 16.636  16.724  23.646  1     17.762 ? 257 VAL A HG22 1 c 
ATOM   908  H HG23 . VAL A 1 89  ? 16.655  16.807  22.061  1     17.772 ? 257 VAL A HG23 1 c 
ATOM   909  N N    . LEU A 1 90  ? 13.991  12.767  21.651  1     16.682 ? 258 LEU A N    1 ? 
ATOM   910  C CA   . LEU A 1 90  ? 13.574  11.376  21.672  1     16.694 ? 258 LEU A CA   1 ? 
ATOM   911  C C    . LEU A 1 90  ? 14.607  10.552  20.914  1     16.495 ? 258 LEU A C    1 ? 
ATOM   912  O O    . LEU A 1 90  ? 15.152  10.997  19.925  1     15.656 ? 258 LEU A O    1 ? 
ATOM   913  C CB   . LEU A 1 90  ? 12.213  11.159  21.027  1     16.324 ? 258 LEU A CB   1 ? 
ATOM   914  C CG   . LEU A 1 90  ? 11.035  11.927  21.633  1     15.278 ? 258 LEU A CG   1 ? 
ATOM   915  C CD1  . LEU A 1 90  ? 9.776   11.623  20.807  1     14.227 ? 258 LEU A CD1  1 ? 
ATOM   916  C CD2  . LEU A 1 90  ? 10.89   11.521  23.11   1     14.568 ? 258 LEU A CD2  1 ? 
ATOM   917  H H    . LEU A 1 90  ? 13.946  13.226  20.862  1     16.315 ? 258 LEU A H    1 c 
ATOM   918  H HA   . LEU A 1 90  ? 13.543  11.066  22.609  1     16.52  ? 258 LEU A HA   1 c 
ATOM   919  H HB2  . LEU A 1 90  ? 12.283  11.403  20.076  1     16.163 ? 258 LEU A HB2  1 c 
ATOM   920  H HB3  . LEU A 1 90  ? 12.006  10.196  21.067  1     16.156 ? 258 LEU A HB3  1 c 
ATOM   921  H HG   . LEU A 1 90  ? 11.227  12.898  21.582  1     15.132 ? 258 LEU A HG   1 c 
ATOM   922  H HD11 . LEU A 1 90  ? 9.912   11.913  19.889  1     14.527 ? 258 LEU A HD11 1 c 
ATOM   923  H HD12 . LEU A 1 90  ? 9.017   12.097  21.186  1     14.527 ? 258 LEU A HD12 1 c 
ATOM   924  H HD13 . LEU A 1 90  ? 9.6     10.668  20.822  1     14.527 ? 258 LEU A HD13 1 c 
ATOM   925  H HD21 . LEU A 1 90  ? 11.596  11.935  23.634  1     14.792 ? 258 LEU A HD21 1 c 
ATOM   926  H HD22 . LEU A 1 90  ? 10.952  10.555  23.189  1     14.777 ? 258 LEU A HD22 1 c 
ATOM   927  H HD23 . LEU A 1 90  ? 10.026  11.815  23.444  1     14.777 ? 258 LEU A HD23 1 c 
ATOM   928  N N    . ALA A 1 91  ? 14.869  9.35    21.447  1     14.139 ? 259 ALA A N    1 ? 
ATOM   929  C CA   . ALA A 1 91  ? 15.763  8.395   20.842  1     14.627 ? 259 ALA A CA   1 ? 
ATOM   930  C C    . ALA A 1 91  ? 14.944  7.471   19.963  1     15.771 ? 259 ALA A C    1 ? 
ATOM   931  O O    . ALA A 1 91  ? 14.137  6.726   20.471  1     16.136 ? 259 ALA A O    1 ? 
ATOM   932  C CB   . ALA A 1 91  ? 16.491  7.604   21.887  1     15.189 ? 259 ALA A CB   1 ? 
ATOM   933  H H    . ALA A 1 91  ? 14.456  9.117   22.228  1     14.812 ? 259 ALA A H    1 c 
ATOM   934  H HA   . ALA A 1 91  ? 16.425  8.88    20.28   1     14.867 ? 259 ALA A HA   1 c 
ATOM   935  H HB1  . ALA A 1 91  ? 17.235  8.123   22.232  1     15.037 ? 259 ALA A HB1  1 c 
ATOM   936  H HB2  . ALA A 1 91  ? 15.886  7.386   22.616  1     15.023 ? 259 ALA A HB2  1 c 
ATOM   937  H HB3  . ALA A 1 91  ? 16.832  6.781   21.498  1     15.027 ? 259 ALA A HB3  1 c 
ATOM   938  N N    . TYR A 1 92  ? 15.185  7.546   18.661  1     16.492 ? 260 TYR A N    1 ? 
ATOM   939  C CA   . TYR A 1 92  ? 14.725  6.56    17.7    1     15.763 ? 260 TYR A CA   1 ? 
ATOM   940  C C    . TYR A 1 92  ? 15.491  5.267   17.897  1     16.493 ? 260 TYR A C    1 ? 
ATOM   941  O O    . TYR A 1 92  ? 16.74   5.247   17.935  1     17.015 ? 260 TYR A O    1 ? 
ATOM   942  C CB   . TYR A 1 92  ? 14.984  7.127   16.3    1     14.761 ? 260 TYR A CB   1 ? 
ATOM   943  C CG   . TYR A 1 92  ? 14.749  6.113   15.201  1     15.424 ? 260 TYR A CG   1 ? 
ATOM   944  C CD1  . TYR A 1 92  ? 15.668  5.127   14.916  1     14.725 ? 260 TYR A CD1  1 ? 
ATOM   945  C CD2  . TYR A 1 92  ? 13.563  6.149   14.477  1     16.502 ? 260 TYR A CD2  1 ? 
ATOM   946  C CE1  . TYR A 1 92  ? 15.434  4.186   13.922  1     17.993 ? 260 TYR A CE1  1 ? 
ATOM   947  C CE2  . TYR A 1 92  ? 13.35   5.241   13.447  1     17.426 ? 260 TYR A CE2  1 ? 
ATOM   948  C CZ   . TYR A 1 92  ? 14.258  4.237   13.213  1     19.275 ? 260 TYR A CZ   1 ? 
ATOM   949  O OH   . TYR A 1 92  ? 14.012  3.268   12.256  1     21.382 ? 260 TYR A OH   1 ? 
ATOM   950  H H    . TYR A 1 92  ? 15.657  8.264   18.348  1     16.109 ? 260 TYR A H    1 c 
ATOM   951  H HA   . TYR A 1 92  ? 13.758  6.41    17.822  1     15.852 ? 260 TYR A HA   1 c 
ATOM   952  H HB2  . TYR A 1 92  ? 14.394  7.9     16.159  1     15.151 ? 260 TYR A HB2  1 c 
ATOM   953  H HB3  . TYR A 1 92  ? 15.915  7.438   16.252  1     15.143 ? 260 TYR A HB3  1 c 
ATOM   954  H HD1  . TYR A 1 92  ? 16.47   5.081   15.409  1     15.658 ? 260 TYR A HD1  1 c 
ATOM   955  H HD2  . TYR A 1 92  ? 12.929  6.828   14.642  1     16.46  ? 260 TYR A HD2  1 c 
ATOM   956  H HE1  . TYR A 1 92  ? 16.063  3.505   13.751  1     17.447 ? 260 TYR A HE1  1 c 
ATOM   957  H HE2  . TYR A 1 92  ? 12.532  5.248   12.98   1     17.604 ? 260 TYR A HE2  1 c 
ATOM   958  N N    . PHE A 1 93  ? 14.734  4.177   17.999  1     16.176 ? 261 PHE A N    1 ? 
ATOM   959  C CA   . PHE A 1 93  ? 15.268  2.856   17.787  1     16.321 ? 261 PHE A CA   1 ? 
ATOM   960  C C    . PHE A 1 93  ? 14.156  1.91    17.375  1     16.744 ? 261 PHE A C    1 ? 
ATOM   961  O O    . PHE A 1 93  ? 12.976  2.148   17.613  1     15.136 ? 261 PHE A O    1 ? 
ATOM   962  C CB   . PHE A 1 93  ? 16.045  2.283   18.995  1     17.356 ? 261 PHE A CB   1 ? 
ATOM   963  C CG   . PHE A 1 93  ? 15.296  2.222   20.316  1     17.172 ? 261 PHE A CG   1 ? 
ATOM   964  C CD1  . PHE A 1 93  ? 14.534  1.116   20.666  1     17.221 ? 261 PHE A CD1  1 ? 
ATOM   965  C CD2  . PHE A 1 93  ? 15.453  3.256   21.253  1     17.166 ? 261 PHE A CD2  1 ? 
ATOM   966  C CE1  . PHE A 1 93  ? 13.899  1.035   21.895  1     18.014 ? 261 PHE A CE1  1 ? 
ATOM   967  C CE2  . PHE A 1 93  ? 14.868  3.149   22.503  1     17.786 ? 261 PHE A CE2  1 ? 
ATOM   968  C CZ   . PHE A 1 93  ? 14.046  2.077   22.813  1     16.989 ? 261 PHE A CZ   1 ? 
ATOM   969  H H    . PHE A 1 93  ? 13.852  4.262   18.224  1     16.279 ? 261 PHE A H    1 c 
ATOM   970  H HA   . PHE A 1 93  ? 15.905  2.914   17.025  1     16.547 ? 261 PHE A HA   1 c 
ATOM   971  H HB2  . PHE A 1 93  ? 16.34   1.375   18.762  1     17.052 ? 261 PHE A HB2  1 c 
ATOM   972  H HB3  . PHE A 1 93  ? 16.856  2.825   19.121  1     17.071 ? 261 PHE A HB3  1 c 
ATOM   973  H HD1  . PHE A 1 93  ? 14.425  0.416   20.042  1     17.391 ? 261 PHE A HD1  1 c 
ATOM   974  H HD2  . PHE A 1 93  ? 16.011  3.991   21.053  1     17.312 ? 261 PHE A HD2  1 c 
ATOM   975  H HE1  . PHE A 1 93  ? 13.36   0.289   22.104  1     17.582 ? 261 PHE A HE1  1 c 
ATOM   976  H HE2  . PHE A 1 93  ? 14.947  3.865   23.114  1     17.452 ? 261 PHE A HE2  1 c 
ATOM   977  H HZ   . PHE A 1 93  ? 13.623  2.03    23.656  1     17.402 ? 261 PHE A HZ   1 c 
ATOM   978  N N    . GLU A 1 94  ? 14.574  0.813   16.738  1     14.466 ? 262 GLU A N    1 ? 
ATOM   979  C CA   . GLU A 1 94  ? 13.653  -0.185  16.245  1     15.432 ? 262 GLU A CA   1 ? 
ATOM   980  C C    . GLU A 1 94  ? 13.381  -1.232  17.318  1     15.917 ? 262 GLU A C    1 ? 
ATOM   981  O O    . GLU A 1 94  ? 14.259  -1.549  18.129  1     16.509 ? 262 GLU A O    1 ? 
ATOM   982  C CB   . GLU A 1 94  ? 14.315  -0.91   15.073  1     15.436 ? 262 GLU A CB   1 ? 
ATOM   983  C CG   . GLU A 1 94  ? 14.557  0.011   13.881  1     17.112 ? 262 GLU A CG   1 ? 
ATOM   984  C CD   . GLU A 1 94  ? 15.415  -0.674  12.822  1     24.332 ? 262 GLU A CD   1 ? 
ATOM   985  O OE1  . GLU A 1 94  ? 15.193  -1.889  12.579  1     26.117 ? 262 GLU A OE1  1 ? 
ATOM   986  O OE2  . GLU A 1 94  ? 16.344  -0.002  12.329  1     36.423 ? 262 GLU A OE2  1 ? 
ATOM   987  H H    . GLU A 1 94  ? 15.471  0.683   16.614  1     15.224 ? 262 GLU A H    1 c 
ATOM   988  H HA   . GLU A 1 94  ? 12.813  0.25    15.96   1     15.345 ? 262 GLU A HA   1 c 
ATOM   989  H HB2  . GLU A 1 94  ? 15.167  -1.29   15.372  1     15.843 ? 262 GLU A HB2  1 c 
ATOM   990  H HB3  . GLU A 1 94  ? 13.738  -1.652  14.793  1     15.851 ? 262 GLU A HB3  1 c 
ATOM   991  H HG2  . GLU A 1 94  ? 13.697  0.263   13.482  1     18.139 ? 262 GLU A HG2  1 c 
ATOM   992  H HG3  . GLU A 1 94  ? 15.011  0.827   14.181  1     18.191 ? 262 GLU A HG3  1 c 
ATOM   993  N N    . ILE A 1 95  ? 12.153  -1.754  17.305  1     14.761 ? 263 ILE A N    1 ? 
ATOM   994  C CA   . ILE A 1 95  ? 11.791  -2.794  18.258  1     16.269 ? 263 ILE A CA   1 ? 
ATOM   995  C C    . ILE A 1 95  ? 11.298  -4.05   17.545  1     17.45  ? 263 ILE A C    1 ? 
ATOM   996  O O    . ILE A 1 95  ? 10.987  -5.034  18.214  1     15.998 ? 263 ILE A O    1 ? 
ATOM   997  C CB   . ILE A 1 95  ? 10.748  -2.304  19.272  1     16.85  ? 263 ILE A CB   1 ? 
ATOM   998  C CG1  . ILE A 1 95  ? 9.409   -1.937  18.663  1     16.547 ? 263 ILE A CG1  1 ? 
ATOM   999  C CG2  . ILE A 1 95  ? 11.356  -1.192  20.124  1     19.356 ? 263 ILE A CG2  1 ? 
ATOM   1000 C CD1  . ILE A 1 95  ? 8.304   -1.668  19.682  1     16.474 ? 263 ILE A CD1  1 ? 
ATOM   1001 H H    . ILE A 1 95  ? 11.52   -1.432  16.729  1     15.379 ? 263 ILE A H    1 c 
ATOM   1002 H HA   . ILE A 1 95  ? 12.591  -3.041  18.76   1     16.292 ? 263 ILE A HA   1 c 
ATOM   1003 H HB   . ILE A 1 95  ? 10.577  -3.053  19.877  1     17.119 ? 263 ILE A HB   1 c 
ATOM   1004 H HG12 . ILE A 1 95  ? 9.526   -1.137  18.111  1     16.608 ? 263 ILE A HG12 1 c 
ATOM   1005 H HG13 . ILE A 1 95  ? 9.117   -2.663  18.076  1     16.605 ? 263 ILE A HG13 1 c 
ATOM   1006 H HG21 . ILE A 1 95  ? 10.774  -1.002  20.878  1     18.547 ? 263 ILE A HG21 1 c 
ATOM   1007 H HG22 . ILE A 1 95  ? 11.459  -0.389  19.586  1     18.542 ? 263 ILE A HG22 1 c 
ATOM   1008 H HG23 . ILE A 1 95  ? 12.226  -1.472  20.454  1     18.552 ? 263 ILE A HG23 1 c 
ATOM   1009 H HD11 . ILE A 1 95  ? 8.272   -2.397  20.331  1     16.498 ? 263 ILE A HD11 1 c 
ATOM   1010 H HD12 . ILE A 1 95  ? 7.444   -1.606  19.224  1     16.498 ? 263 ILE A HD12 1 c 
ATOM   1011 H HD13 . ILE A 1 95  ? 8.484   -0.829  20.147  1     16.508 ? 263 ILE A HD13 1 c 
ATOM   1012 N N    . GLY A 1 96  ? 11.312  -4.031  16.212  1     16.612 ? 264 GLY A N    1 ? 
ATOM   1013 C CA   . GLY A 1 96  ? 10.702  -5.089  15.422  1     15.936 ? 264 GLY A CA   1 ? 
ATOM   1014 C C    . GLY A 1 96  ? 11.61   -5.728  14.41   1     17.929 ? 264 GLY A C    1 ? 
ATOM   1015 O O    . GLY A 1 96  ? 11.148  -6.591  13.643  1     20.478 ? 264 GLY A O    1 ? 
ATOM   1016 H H    . GLY A 1 96  ? 11.713  -3.339  15.771  1     16.641 ? 264 GLY A H    1 c 
ATOM   1017 H HA2  . GLY A 1 96  ? 10.366  -5.789  16.028  1     16.536 ? 264 GLY A HA2  1 c 
ATOM   1018 H HA3  . GLY A 1 96  ? 9.925   -4.715  14.953  1     16.544 ? 264 GLY A HA3  1 c 
ATOM   1019 N N    . ALA A 1 97  ? 12.878  -5.304  14.358  1     17.844 ? 265 ALA A N    1 ? 
ATOM   1020 C CA   . ALA A 1 97  ? 13.756  -5.787  13.316  1     17.244 ? 265 ALA A CA   1 ? 
ATOM   1021 C C    . ALA A 1 97  ? 15.184  -5.581  13.804  1     17.722 ? 265 ALA A C    1 ? 
ATOM   1022 O O    . ALA A 1 97  ? 15.432  -4.775  14.696  1     18.012 ? 265 ALA A O    1 ? 
ATOM   1023 C CB   . ALA A 1 97  ? 13.524  -5.05   12.012  1     18.79  ? 265 ALA A CB   1 ? 
ATOM   1024 H H    . ALA A 1 97  ? 13.205  -4.725  14.984  1     17.696 ? 265 ALA A H    1 c 
ATOM   1025 H HA   . ALA A 1 97  ? 13.6    -6.761  13.19   1     17.749 ? 265 ALA A HA   1 c 
ATOM   1026 H HB1  . ALA A 1 97  ? 12.635  -5.253  11.675  1     18.32  ? 265 ALA A HB1  1 c 
ATOM   1027 H HB2  . ALA A 1 97  ? 13.6    -4.092  12.16   1     18.32  ? 265 ALA A HB2  1 c 
ATOM   1028 H HB3  . ALA A 1 97  ? 14.186  -5.327  11.357  1     18.325 ? 265 ALA A HB3  1 c 
ATOM   1029 N N    . ILE A 1 98  ? 16.105  -6.262  13.164  1     18.011 ? 266 ILE A N    1 ? 
ATOM   1030 C CA   . ILE A 1 98  ? 17.531  -6.096  13.444  1     19.163 ? 266 ILE A CA   1 ? 
ATOM   1031 C C    . ILE A 1 98  ? 18.272  -6.027  12.116  1     21.742 ? 266 ILE A C    1 ? 
ATOM   1032 O O    . ILE A 1 98  ? 17.882  -6.671  11.15   1     21.146 ? 266 ILE A O    1 ? 
ATOM   1033 C CB   . ILE A 1 98  ? 18.044  -7.257  14.325  1     18.392 ? 266 ILE A CB   1 ? 
ATOM   1034 C CG1  . ILE A 1 98  ? 19.46   -7.026  14.887  1     19.262 ? 266 ILE A CG1  1 ? 
ATOM   1035 C CG2  . ILE A 1 98  ? 17.972  -8.598  13.604  1     20.762 ? 266 ILE A CG2  1 ? 
ATOM   1036 C CD1  . ILE A 1 98  ? 19.611  -5.825  15.794  1     17.834 ? 266 ILE A CD1  1 ? 
ATOM   1037 H H    . ILE A 1 98  ? 15.851  -6.855  12.515  1     18.217 ? 266 ILE A H    1 c 
ATOM   1038 H HA   . ILE A 1 98  ? 17.665  -5.258  13.92   1     19.204 ? 266 ILE A HA   1 c 
ATOM   1039 H HB   . ILE A 1 98  ? 17.442  -7.314  15.094  1     19.125 ? 266 ILE A HB   1 c 
ATOM   1040 H HG12 . ILE A 1 98  ? 19.724  -7.824  15.389  1     18.741 ? 266 ILE A HG12 1 c 
ATOM   1041 H HG13 . ILE A 1 98  ? 20.084  -6.933  14.14   1     18.806 ? 266 ILE A HG13 1 c 
ATOM   1042 H HG21 . ILE A 1 98  ? 17.997  -9.318  14.257  1     20.034 ? 266 ILE A HG21 1 c 
ATOM   1043 H HG22 . ILE A 1 98  ? 18.729  -8.687  13.001  1     20.056 ? 266 ILE A HG22 1 c 
ATOM   1044 H HG23 . ILE A 1 98  ? 17.147  -8.657  13.096  1     20.015 ? 266 ILE A HG23 1 c 
ATOM   1045 H HD11 . ILE A 1 98  ? 19.554  -5.005  15.267  1     18.29  ? 266 ILE A HD11 1 c 
ATOM   1046 H HD12 . ILE A 1 98  ? 20.478  -5.863  16.238  1     18.271 ? 266 ILE A HD12 1 c 
ATOM   1047 H HD13 . ILE A 1 98  ? 18.902  -5.829  16.465  1     18.259 ? 266 ILE A HD13 1 c 
ATOM   1048 N N    . GLU A 1 99  ? 19.424  -5.381  12.119  1     22.138 ? 267 GLU A N    1 ? 
ATOM   1049 C CA   . GLU A 1 99  ? 20.224  -5.206  10.927  1     22.638 ? 267 GLU A CA   1 ? 
ATOM   1050 C C    . GLU A 1 99  ? 21.653  -5.61   11.25   1     23.267 ? 267 GLU A C    1 ? 
ATOM   1051 O O    . GLU A 1 99  ? 22.148  -5.43   12.38   1     21.223 ? 267 GLU A O    1 ? 
ATOM   1052 C CB   . GLU A 1 99  ? 20.188  -3.777  10.411  1     25.234 ? 267 GLU A CB   1 ? 
ATOM   1053 C CG   . GLU A 1 99  ? 18.796  -3.263  10.059  1     27.299 ? 267 GLU A CG   1 ? 
ATOM   1054 C CD   . GLU A 1 99  ? 17.956  -2.808  11.231  1     28.419 ? 267 GLU A CD   1 ? 
ATOM   1055 O OE1  . GLU A 1 99  ? 18.553  -2.467  12.282  1     26.637 ? 267 GLU A OE1  1 ? 
ATOM   1056 O OE2  . GLU A 1 99  ? 16.705  -2.85   11.075  1     24.6   ? 267 GLU A OE2  1 ? 
ATOM   1057 H H    . GLU A 1 99  ? 19.724  -5.013  12.9    1     22.04  ? 267 GLU A H    1 c 
ATOM   1058 H HA   . GLU A 1 99  ? 19.876  -5.803  10.225  1     23.136 ? 267 GLU A HA   1 c 
ATOM   1059 H HB2  . GLU A 1 99  ? 20.6    -3.19   11.078  1     25.061 ? 267 GLU A HB2  1 c 
ATOM   1060 H HB3  . GLU A 1 99  ? 20.736  -3.733  9.602   1     25.092 ? 267 GLU A HB3  1 c 
ATOM   1061 H HG2  . GLU A 1 99  ? 18.878  -2.52   9.432   1     27.191 ? 267 GLU A HG2  1 c 
ATOM   1062 H HG3  . GLU A 1 99  ? 18.307  -3.977  9.598   1     27.107 ? 267 GLU A HG3  1 c 
ATOM   1063 N N    . GLU A 1 100 ? 22.332  -6.166  10.225  1     24.72  ? 268 GLU A N    1 ? 
ATOM   1064 C CA   . GLU A 1 100 ? 23.676  -6.683  10.388  1     25.392 ? 268 GLU A CA   1 ? 
ATOM   1065 C C    . GLU A 1 100 ? 24.659  -5.606  10.826  1     23.958 ? 268 GLU A C    1 ? 
ATOM   1066 O O    . GLU A 1 100 ? 25.655  -5.894  11.497  1     26.927 ? 268 GLU A O    1 ? 
ATOM   1067 C CB   . GLU A 1 100 ? 24.142  -7.391  9.113   1     29.267 ? 268 GLU A CB   1 ? 
ATOM   1068 C CG   . GLU A 1 100 ? 25.457  -8.124  9.336   1     29.746 ? 268 GLU A CG   1 ? 
ATOM   1069 C CD   . GLU A 1 100 ? 26.724  -7.307  9.145   1     37.896 ? 268 GLU A CD   1 ? 
ATOM   1070 O OE1  . GLU A 1 100 ? 27.748  -7.842  9.611   1     40.354 ? 268 GLU A OE1  1 ? 
ATOM   1071 O OE2  . GLU A 1 100 ? 26.722  -6.198  8.526   1     40.436 ? 268 GLU A OE2  1 ? 
ATOM   1072 H H    . GLU A 1 100 ? 21.94   -6.214  9.401   1     24.519 ? 268 GLU A H    1 c 
ATOM   1073 H HA   . GLU A 1 100 ? 23.648  -7.35   11.1    1     25.65  ? 268 GLU A HA   1 c 
ATOM   1074 H HB2  . GLU A 1 100 ? 23.457  -8.035  8.84    1     28.459 ? 268 GLU A HB2  1 c 
ATOM   1075 H HB3  . GLU A 1 100 ? 24.235  -6.731  8.396   1     28.526 ? 268 GLU A HB3  1 c 
ATOM   1076 H HG2  . GLU A 1 100 ? 25.464  -8.489  10.246  1     31.277 ? 268 GLU A HG2  1 c 
ATOM   1077 H HG3  . GLU A 1 100 ? 25.494  -8.889  8.723   1     31.327 ? 268 GLU A HG3  1 c 
ATOM   1078 N N    . TYR A 1 101 ? 24.384  -4.364  10.456  1     23.196 ? 269 TYR A N    1 ? 
ATOM   1079 C CA   . TYR A 1 101 ? 25.279  -3.26   10.753  1     25.781 ? 269 TYR A CA   1 ? 
ATOM   1080 C C    . TYR A 1 101 ? 25.031  -2.724  12.165  1     26.585 ? 269 TYR A C    1 ? 
ATOM   1081 O O    . TYR A 1 101 ? 25.749  -1.833  12.609  1     28.336 ? 269 TYR A O    1 ? 
ATOM   1082 C CB   . TYR A 1 101 ? 25.135  -2.147  9.715   1     26.573 ? 269 TYR A CB   1 ? 
ATOM   1083 C CG   . TYR A 1 101 ? 23.715  -1.724  9.387   1     27.823 ? 269 TYR A CG   1 ? 
ATOM   1084 C CD1  . TYR A 1 101 ? 23.035  -0.806  10.179  1     28.602 ? 269 TYR A CD1  1 ? 
ATOM   1085 C CD2  . TYR A 1 101 ? 23.078  -2.213  8.26    1     30.887 ? 269 TYR A CD2  1 ? 
ATOM   1086 C CE1  . TYR A 1 101 ? 21.741  -0.418  9.862   1     33.461 ? 269 TYR A CE1  1 ? 
ATOM   1087 C CE2  . TYR A 1 101 ? 21.779  -1.85   7.94    1     32.444 ? 269 TYR A CE2  1 ? 
ATOM   1088 C CZ   . TYR A 1 101 ? 21.119  -0.93   8.738   1     34.946 ? 269 TYR A CZ   1 ? 
ATOM   1089 O OH   . TYR A 1 101 ? 19.841  -0.558  8.421   1     44.498 ? 269 TYR A OH   1 ? 
ATOM   1090 H H    . TYR A 1 101 ? 23.619  -4.196  9.988   1     24.027 ? 269 TYR A H    1 c 
ATOM   1091 H HA   . TYR A 1 101 ? 26.214  -3.596  10.709  1     25.537 ? 269 TYR A HA   1 c 
ATOM   1092 H HB2  . TYR A 1 101 ? 25.631  -1.36   10.033  1     26.687 ? 269 TYR A HB2  1 c 
ATOM   1093 H HB3  . TYR A 1 101 ? 25.571  -2.445  8.885   1     26.716 ? 269 TYR A HB3  1 c 
ATOM   1094 H HD1  . TYR A 1 101 ? 23.453  -0.449  10.945  1     29.552 ? 269 TYR A HD1  1 c 
ATOM   1095 H HD2  . TYR A 1 101 ? 23.527  -2.839  7.714   1     30.497 ? 269 TYR A HD2  1 c 
ATOM   1096 H HE1  . TYR A 1 101 ? 21.287  0.199   10.41   1     32.589 ? 269 TYR A HE1  1 c 
ATOM   1097 H HE2  . TYR A 1 101 ? 21.362  -2.198  7.171   1     32.632 ? 269 TYR A HE2  1 c 
ATOM   1098 N N    . ARG A 1 102 ? 24.046  -3.272  12.886  1     22.033 ? 270 ARG A N    1 ? 
ATOM   1099 C CA   . ARG A 1 102 ? 23.812  -2.886  14.267  1     24.791 ? 270 ARG A CA   1 ? 
ATOM   1100 C C    . ARG A 1 102 ? 24.531  -3.837  15.223  1     21.311 ? 270 ARG A C    1 ? 
ATOM   1101 O O    . ARG A 1 102 ? 24.703  -5.009  14.932  1     20.349 ? 270 ARG A O    1 ? 
ATOM   1102 C CB   . ARG A 1 102 ? 22.315  -2.827  14.597  1     24.172 ? 270 ARG A CB   1 ? 
ATOM   1103 C CG   . ARG A 1 102 ? 21.802  -1.57   13.902  1     26.299 ? 270 ARG A CG   1 ? 
ATOM   1104 C CD   . ARG A 1 102 ? 20.528  -1.091  14.426  1     24.287 ? 270 ARG A CD   1 ? 
ATOM   1105 N NE   . ARG A 1 102 ? 19.89   -0.134  13.525  1     22.15  ? 270 ARG A NE   1 ? 
ATOM   1106 C CZ   . ARG A 1 102 ? 19.801  1.164   13.714  1     24.148 ? 270 ARG A CZ   1 ? 
ATOM   1107 N NH1  . ARG A 1 102 ? 20.613  1.795   14.555  1     20.603 ? 270 ARG A NH1  1 ? 
ATOM   1108 N NH2  . ARG A 1 102 ? 18.936  1.831   12.981  1     24.928 ? 270 ARG A NH2  1 ? 
ATOM   1109 H H    . ARG A 1 102 ? 23.483  -3.881  12.506  1     23.674 ? 270 ARG A H    1 c 
ATOM   1110 H HA   . ARG A 1 102 ? 24.189  -1.982  14.399  1     23.477 ? 270 ARG A HA   1 c 
ATOM   1111 H HB2  . ARG A 1 102 ? 21.85   -3.619  14.253  1     24.746 ? 270 ARG A HB2  1 c 
ATOM   1112 H HB3  . ARG A 1 102 ? 22.171  -2.763  15.565  1     24.722 ? 270 ARG A HB3  1 c 
ATOM   1113 H HG2  . ARG A 1 102 ? 22.464  -0.85   13.993  1     25.3   ? 270 ARG A HG2  1 c 
ATOM   1114 H HG3  . ARG A 1 102 ? 21.7    -1.755  12.943  1     25.298 ? 270 ARG A HG3  1 c 
ATOM   1115 H HD2  . ARG A 1 102 ? 19.931  -1.856  14.552  1     24.156 ? 270 ARG A HD2  1 c 
ATOM   1116 H HD3  . ARG A 1 102 ? 20.668  -0.676  15.3    1     24.184 ? 270 ARG A HD3  1 c 
ATOM   1117 H HE   . ARG A 1 102 ? 19.538  -0.452  12.794  1     23.11  ? 270 ARG A HE   1 c 
ATOM   1118 H HH11 . ARG A 1 102 ? 21.484  1.645   14.521  1     21.649 ? 270 ARG A HH11 1 c 
ATOM   1119 H HH12 . ARG A 1 102 ? 20.279  2.363   15.145  1     21.639 ? 270 ARG A HH12 1 c 
ATOM   1120 H HH21 . ARG A 1 102 ? 18.121  1.51    12.862  1     24.683 ? 270 ARG A HH21 1 c 
ATOM   1121 H HH22 . ARG A 1 102 ? 19.173  2.598   12.61   1     24.677 ? 270 ARG A HH22 1 c 
ATOM   1122 N N    . PRO A 1 103 ? 24.959  -3.334  16.39   1     20.954 ? 271 PRO A N    1 ? 
ATOM   1123 C CA   . PRO A 1 103 ? 25.864  -4.106  17.243  1     19.662 ? 271 PRO A CA   1 ? 
ATOM   1124 C C    . PRO A 1 103 ? 25.235  -5.371  17.816  1     22.185 ? 271 PRO A C    1 ? 
ATOM   1125 O O    . PRO A 1 103 ? 25.946  -6.292  18.178  1     22.474 ? 271 PRO A O    1 ? 
ATOM   1126 C CB   . PRO A 1 103 ? 26.234  -3.085  18.359  1     22.661 ? 271 PRO A CB   1 ? 
ATOM   1127 C CG   . PRO A 1 103 ? 25.077  -2.11   18.36   1     20.958 ? 271 PRO A CG   1 ? 
ATOM   1128 C CD   . PRO A 1 103 ? 24.757  -1.959  16.878  1     20.441 ? 271 PRO A CD   1 ? 
ATOM   1129 H HA   . PRO A 1 103 ? 26.675  -4.339  16.725  1     20.872 ? 271 PRO A HA   1 c 
ATOM   1130 H HB2  . PRO A 1 103 ? 26.319  -3.531  19.234  1     21.588 ? 271 PRO A HB2  1 c 
ATOM   1131 H HB3  . PRO A 1 103 ? 27.081  -2.629  18.15   1     21.601 ? 271 PRO A HB3  1 c 
ATOM   1132 H HG2  . PRO A 1 103 ? 24.31   -2.47   18.852  1     21.212 ? 271 PRO A HG2  1 c 
ATOM   1133 H HG3  . PRO A 1 103 ? 25.337  -1.251  18.754  1     21.212 ? 271 PRO A HG3  1 c 
ATOM   1134 H HD2  . PRO A 1 103 ? 23.832  -1.658  16.744  1     20.748 ? 271 PRO A HD2  1 c 
ATOM   1135 H HD3  . PRO A 1 103 ? 25.375  -1.334  16.442  1     20.693 ? 271 PRO A HD3  1 c 
ATOM   1136 N N    . GLU A 1 104 ? 23.903  -5.415  17.943  1     18.446 ? 272 GLU A N    1 ? 
ATOM   1137 C CA   . GLU A 1 104 ? 23.268  -6.551  18.58   1     18.561 ? 272 GLU A CA   1 ? 
ATOM   1138 C C    . GLU A 1 104 ? 23.067  -7.71   17.584  1     21.165 ? 272 GLU A C    1 ? 
ATOM   1139 O O    . GLU A 1 104 ? 22.595  -8.755  17.99   1     22.626 ? 272 GLU A O    1 ? 
ATOM   1140 C CB   . GLU A 1 104 ? 21.892  -6.165  19.144  1     21.356 ? 272 GLU A CB   1 ? 
ATOM   1141 C CG   . GLU A 1 104 ? 21.946  -4.991  20.131  1     20.422 ? 272 GLU A CG   1 ? 
ATOM   1142 C CD   . GLU A 1 104 ? 21.581  -3.642  19.496  1     20.282 ? 272 GLU A CD   1 ? 
ATOM   1143 O OE1  . GLU A 1 104 ? 21.758  -3.548  18.259  1     20.445 ? 272 GLU A OE1  1 ? 
ATOM   1144 O OE2  . GLU A 1 104 ? 21.153  -2.679  20.223  1     20.615 ? 272 GLU A OE2  1 ? 
ATOM   1145 H H    . GLU A 1 104 ? 23.382  -4.732  17.632  1     19.351 ? 272 GLU A H    1 c 
ATOM   1146 H HA   . GLU A 1 104 ? 23.84   -6.863  19.328  1     19.505 ? 272 GLU A HA   1 c 
ATOM   1147 H HB2  . GLU A 1 104 ? 21.289  -5.958  18.401  1     20.472 ? 272 GLU A HB2  1 c 
ATOM   1148 H HB3  . GLU A 1 104 ? 21.523  -6.939  19.615  1     20.508 ? 272 GLU A HB3  1 c 
ATOM   1149 H HG2  . GLU A 1 104 ? 21.327  -5.165  20.872  1     20.595 ? 272 GLU A HG2  1 c 
ATOM   1150 H HG3  . GLU A 1 104 ? 22.85   -4.926  20.506  1     20.585 ? 272 GLU A HG3  1 c 
ATOM   1151 N N    . TRP A 1 105 ? 23.396  -7.531  16.305  1     20.994 ? 273 TRP A N    1 ? 
ATOM   1152 C CA   . TRP A 1 105 ? 23.147  -8.555  15.29   1     21.764 ? 273 TRP A CA   1 ? 
ATOM   1153 C C    . TRP A 1 105 ? 23.586  -9.948  15.74   1     25.5   ? 273 TRP A C    1 ? 
ATOM   1154 O O    . TRP A 1 105 ? 22.834  -10.903 15.584  1     25.219 ? 273 TRP A O    1 ? 
ATOM   1155 C CB   . TRP A 1 105 ? 23.83   -8.166  13.985  1     22.958 ? 273 TRP A CB   1 ? 
ATOM   1156 C CG   . TRP A 1 105 ? 23.727  -9.196  12.889  1     23.333 ? 273 TRP A CG   1 ? 
ATOM   1157 C CD1  . TRP A 1 105 ? 24.722  -10.049 12.511  1     25.117 ? 273 TRP A CD1  1 ? 
ATOM   1158 C CD2  . TRP A 1 105 ? 22.625  -9.429  11.991  1     22.467 ? 273 TRP A CD2  1 ? 
ATOM   1159 N NE1  . TRP A 1 105 ? 24.316  -10.798 11.437  1     24.69  ? 273 TRP A NE1  1 ? 
ATOM   1160 C CE2  . TRP A 1 105 ? 23.044  -10.435 11.084  1     26.218 ? 273 TRP A CE2  1 ? 
ATOM   1161 C CE3  . TRP A 1 105 ? 21.344  -8.879  11.848  1     24.736 ? 273 TRP A CE3  1 ? 
ATOM   1162 C CZ2  . TRP A 1 105 ? 22.225  -10.909 10.063  1     25.69  ? 273 TRP A CZ2  1 ? 
ATOM   1163 C CZ3  . TRP A 1 105 ? 20.554  -9.318  10.81   1     23.144 ? 273 TRP A CZ3  1 ? 
ATOM   1164 C CH2  . TRP A 1 105 ? 20.999  -10.301 9.906   1     24.243 ? 273 TRP A CH2  1 ? 
ATOM   1165 H H    . TRP A 1 105 ? 23.774  -6.744  16.04   1     21.182 ? 273 TRP A H    1 c 
ATOM   1166 H HA   . TRP A 1 105 ? 22.167  -8.582  15.122  1     22.484 ? 273 TRP A HA   1 c 
ATOM   1167 H HB2  . TRP A 1 105 ? 23.436  -7.326  13.668  1     22.756 ? 273 TRP A HB2  1 c 
ATOM   1168 H HB3  . TRP A 1 105 ? 24.779  -7.996  14.171  1     22.763 ? 273 TRP A HB3  1 c 
ATOM   1169 H HD1  . TRP A 1 105 ? 25.573  -10.112 12.914  1     24.597 ? 273 TRP A HD1  1 c 
ATOM   1170 H HE1  . TRP A 1 105 ? 24.796  -11.409 11.039  1     25.114 ? 273 TRP A HE1  1 c 
ATOM   1171 H HE3  . TRP A 1 105 ? 21.05   -8.193  12.421  1     23.798 ? 273 TRP A HE3  1 c 
ATOM   1172 H HZ2  . TRP A 1 105 ? 22.529  -11.563 9.457   1     25.415 ? 273 TRP A HZ2  1 c 
ATOM   1173 H HZ3  . TRP A 1 105 ? 19.691  -8.953  10.703  1     23.779 ? 273 TRP A HZ3  1 c 
ATOM   1174 H HH2  . TRP A 1 105 ? 20.413  -10.613 9.24    1     24.372 ? 273 TRP A HH2  1 c 
ATOM   1175 N N    . SER A 1 106 ? 24.795  -10.052 16.303  1     30.191 ? 274 SER A N    1 ? 
ATOM   1176 C CA   . SER A 1 106 ? 25.395  -11.327 16.674  1     29.88  ? 274 SER A CA   1 ? 
ATOM   1177 C C    . SER A 1 106 ? 24.693  -11.97  17.868  1     31.643 ? 274 SER A C    1 ? 
ATOM   1178 O O    . SER A 1 106 ? 24.848  -13.169 18.09   1     33.019 ? 274 SER A O    1 ? 
ATOM   1179 C CB   . SER A 1 106 ? 26.863  -11.181 16.939  1     32.398 ? 274 SER A CB   1 ? 
ATOM   1180 O OG   . SER A 1 106 ? 27.072  -10.362 18.081  1     34.051 ? 274 SER A OG   1 ? 
ATOM   1181 H H    . SER A 1 106 ? 25.274  -9.289  16.458  1     28.793 ? 274 SER A H    1 c 
ATOM   1182 H HA   . SER A 1 106 ? 25.29   -11.94  15.903  1     30.66  ? 274 SER A HA   1 c 
ATOM   1183 H HB2  . SER A 1 106 ? 27.255  -12.062 17.091  1     32.184 ? 274 SER A HB2  1 c 
ATOM   1184 H HB3  . SER A 1 106 ? 27.296  -10.778 16.163  1     32.184 ? 274 SER A HB3  1 c 
ATOM   1185 N N    . GLN A 1 107 ? 23.898  -11.202 18.624  1     27.555 ? 275 GLN A N    1 ? 
ATOM   1186 C CA   . GLN A 1 107 ? 23.088  -11.746 19.693  1     29.076 ? 275 GLN A CA   1 ? 
ATOM   1187 C C    . GLN A 1 107 ? 21.758  -12.295 19.192  1     29.024 ? 275 GLN A C    1 ? 
ATOM   1188 O O    . GLN A 1 107 ? 20.979  -12.822 19.996  1     32.957 ? 275 GLN A O    1 ? 
ATOM   1189 C CB   . GLN A 1 107 ? 22.663  -10.683 20.714  1     30.476 ? 275 GLN A CB   1 ? 
ATOM   1190 C CG   . GLN A 1 107 ? 23.798  -10     21.464  1     35.466 ? 275 GLN A CG   1 ? 
ATOM   1191 C CD   . GLN A 1 107 ? 23.282  -8.827  22.278  1     39.663 ? 275 GLN A CD   1 ? 
ATOM   1192 O OE1  . GLN A 1 107 ? 23.762  -7.7    22.149  1     44.057 ? 275 GLN A OE1  1 ? 
ATOM   1193 N NE2  . GLN A 1 107 ? 22.276  -9.079  23.105  1     37.146 ? 275 GLN A NE2  1 ? 
ATOM   1194 H H    . GLN A 1 107 ? 23.885  -10.298 18.491  1     28.788 ? 275 GLN A H    1 c 
ATOM   1195 H HA   . GLN A 1 107 ? 23.592  -12.466 20.152  1     29.043 ? 275 GLN A HA   1 c 
ATOM   1196 H HB2  . GLN A 1 107 ? 22.14   -9.998  20.248  1     31.199 ? 275 GLN A HB2  1 c 
ATOM   1197 H HB3  . GLN A 1 107 ? 22.072  -11.103 21.373  1     31.244 ? 275 GLN A HB3  1 c 
ATOM   1198 H HG2  . GLN A 1 107 ? 24.23   -10.645 22.064  1     35.151 ? 275 GLN A HG2  1 c 
ATOM   1199 H HG3  . GLN A 1 107 ? 24.465  -9.685  20.828  1     35.147 ? 275 GLN A HG3  1 c 
ATOM   1200 H HE21 . GLN A 1 107 ? 21.649  -8.465  23.238  1     37.899 ? 275 GLN A HE21 1 c 
ATOM   1201 H HE22 . GLN A 1 107 ? 22.231  -9.86   23.523  1     37.886 ? 275 GLN A HE22 1 c 
ATOM   1202 N N    . VAL A 1 108 ? 21.452  -12.135 17.9    1     27.648 ? 276 VAL A N    1 ? 
ATOM   1203 C CA   . VAL A 1 108 ? 20.182  -12.604 17.392  1     26.592 ? 276 VAL A CA   1 ? 
ATOM   1204 C C    . VAL A 1 108 ? 20.394  -13.935 16.659  1     28.579 ? 276 VAL A C    1 ? 
ATOM   1205 O O    . VAL A 1 108 ? 20.879  -13.948 15.546  1     30.398 ? 276 VAL A O    1 ? 
ATOM   1206 C CB   . VAL A 1 108 ? 19.505  -11.548 16.497  1     24.621 ? 276 VAL A CB   1 ? 
ATOM   1207 C CG1  . VAL A 1 108 ? 18.25   -12.095 15.866  1     25.303 ? 276 VAL A CG1  1 ? 
ATOM   1208 C CG2  . VAL A 1 108 ? 19.172  -10.268 17.269  1     22.961 ? 276 VAL A CG2  1 ? 
ATOM   1209 H H    . VAL A 1 108 ? 22.03   -11.72  17.328  1     27.74  ? 276 VAL A H    1 c 
ATOM   1210 H HA   . VAL A 1 108 ? 19.592  -12.759 18.146  1     26.924 ? 276 VAL A HA   1 c 
ATOM   1211 H HB   . VAL A 1 108 ? 20.14   -11.32  15.777  1     24.782 ? 276 VAL A HB   1 c 
ATOM   1212 H HG11 . VAL A 1 108 ? 17.735  -12.568 16.537  1     25.146 ? 276 VAL A HG11 1 c 
ATOM   1213 H HG12 . VAL A 1 108 ? 18.483  -12.705 15.145  1     25.121 ? 276 VAL A HG12 1 c 
ATOM   1214 H HG13 . VAL A 1 108 ? 17.719  -11.364 15.508  1     25.089 ? 276 VAL A HG13 1 c 
ATOM   1215 H HG21 . VAL A 1 108 ? 18.77   -9.62   16.667  1     23.459 ? 276 VAL A HG21 1 c 
ATOM   1216 H HG22 . VAL A 1 108 ? 19.985  -9.895  17.647  1     23.467 ? 276 VAL A HG22 1 c 
ATOM   1217 H HG23 . VAL A 1 108 ? 18.548  -10.475 17.985  1     23.473 ? 276 VAL A HG23 1 c 
ATOM   1218 N N    . PRO A 1 109 ? 19.989  -15.086 17.238  1     32.248 ? 277 PRO A N    1 ? 
ATOM   1219 C CA   . PRO A 1 109 ? 20.08   -16.354 16.533  1     34.161 ? 277 PRO A CA   1 ? 
ATOM   1220 C C    . PRO A 1 109 ? 19.061  -16.473 15.403  1     31.861 ? 277 PRO A C    1 ? 
ATOM   1221 O O    . PRO A 1 109 ? 18.054  -15.758 15.351  1     25.337 ? 277 PRO A O    1 ? 
ATOM   1222 C CB   . PRO A 1 109 ? 19.831  -17.385 17.649  1     36.235 ? 277 PRO A CB   1 ? 
ATOM   1223 C CG   . PRO A 1 109 ? 18.929  -16.662 18.611  1     35.918 ? 277 PRO A CG   1 ? 
ATOM   1224 C CD   . PRO A 1 109 ? 19.424  -15.238 18.593  1     33.979 ? 277 PRO A CD   1 ? 
ATOM   1225 H HA   . PRO A 1 109 ? 20.997  -16.466 16.177  1     33.621 ? 277 PRO A HA   1 c 
ATOM   1226 H HB2  . PRO A 1 109 ? 19.394  -18.192 17.295  1     35.68  ? 277 PRO A HB2  1 c 
ATOM   1227 H HB3  . PRO A 1 109 ? 20.677  -17.644 18.085  1     35.691 ? 277 PRO A HB3  1 c 
ATOM   1228 H HG2  . PRO A 1 109 ? 17.995  -16.71  18.318  1     35.539 ? 277 PRO A HG2  1 c 
ATOM   1229 H HG3  . PRO A 1 109 ? 18.999  -17.044 19.511  1     35.54  ? 277 PRO A HG3  1 c 
ATOM   1230 H HD2  . PRO A 1 109 ? 18.683  -14.612 18.745  1     33.878 ? 277 PRO A HD2  1 c 
ATOM   1231 H HD3  . PRO A 1 109 ? 20.111  -15.1   19.281  1     33.966 ? 277 PRO A HD3  1 c 
ATOM   1232 N N    . ALA A 1 110 ? 19.316  -17.457 14.538  1     26.079 ? 278 ALA A N    1 ? 
ATOM   1233 C CA   . ALA A 1 110 ? 18.483  -17.708 13.385  1     26.262 ? 278 ALA A CA   1 ? 
ATOM   1234 C C    . ALA A 1 110 ? 17.046  -17.909 13.818  1     24.745 ? 278 ALA A C    1 ? 
ATOM   1235 O O    . ALA A 1 110 ? 16.154  -17.507 13.093  1     25.61  ? 278 ALA A O    1 ? 
ATOM   1236 C CB   . ALA A 1 110 ? 18.998  -18.923 12.633  1     27.151 ? 278 ALA A CB   1 ? 
ATOM   1237 H H    . ALA A 1 110 ? 20.042  -17.995 14.679  1     27.482 ? 278 ALA A H    1 c 
ATOM   1238 H HA   . ALA A 1 110 ? 18.523  -16.91  12.789  1     26.094 ? 278 ALA A HA   1 c 
ATOM   1239 H HB1  . ALA A 1 110 ? 19.915  -18.767 12.35   1     26.886 ? 278 ALA A HB1  1 c 
ATOM   1240 H HB2  . ALA A 1 110 ? 18.969  -19.703 13.212  1     26.886 ? 278 ALA A HB2  1 c 
ATOM   1241 H HB3  . ALA A 1 110 ? 18.444  -19.083 11.851  1     26.886 ? 278 ALA A HB3  1 c 
ATOM   1242 N N    . ASP A 1 111 ? 16.836  -18.536 14.983  1     23.536 ? 279 ASP A N    1 ? 
ATOM   1243 C CA   . ASP A 1 111 ? 15.494  -18.826 15.468  1     27.031 ? 279 ASP A CA   1 ? 
ATOM   1244 C C    . ASP A 1 111 ? 14.708  -17.566 15.808  1     27.755 ? 279 ASP A C    1 ? 
ATOM   1245 O O    . ASP A 1 111 ? 13.49   -17.661 15.932  1     34.253 ? 279 ASP A O    1 ? 
ATOM   1246 C CB   . ASP A 1 111 ? 15.527  -19.739 16.695  1     32.38  ? 279 ASP A CB   1 ? 
ATOM   1247 C CG   . ASP A 1 111 ? 14.16   -20.241 17.134  1     40.373 ? 279 ASP A CG   1 ? 
ATOM   1248 O OD1  . ASP A 1 111 ? 13.407  -20.72  16.272  1     37.643 ? 279 ASP A OD1  1 ? 
ATOM   1249 O OD2  . ASP A 1 111 ? 13.846  -20.146 18.327  1     44.221 ? 279 ASP A OD2  1 ? 
ATOM   1250 H H    . ASP A 1 111 ? 17.549  -18.819 15.48   1     24.677 ? 279 ASP A H    1 c 
ATOM   1251 H HA   . ASP A 1 111 ? 15.01   -19.285 14.753  1     27.355 ? 279 ASP A HA   1 c 
ATOM   1252 H HB2  . ASP A 1 111 ? 16.08   -20.52  16.493  1     32.744 ? 279 ASP A HB2  1 c 
ATOM   1253 H HB3  . ASP A 1 111 ? 15.939  -19.256 17.442  1     32.766 ? 279 ASP A HB3  1 c 
ATOM   1254 N N    . LEU A 1 112 ? 15.373  -16.403 15.963  1     25.138 ? 280 LEU A N    1 ? 
ATOM   1255 C CA   . LEU A 1 112 ? 14.662  -15.153 16.209  1     23.083 ? 280 LEU A CA   1 ? 
ATOM   1256 C C    . LEU A 1 112 ? 14.32   -14.444 14.899  1     25.819 ? 280 LEU A C    1 ? 
ATOM   1257 O O    . LEU A 1 112 ? 13.543  -13.491 14.898  1     24.309 ? 280 LEU A O    1 ? 
ATOM   1258 C CB   . LEU A 1 112 ? 15.499  -14.21  17.069  1     28.984 ? 280 LEU A CB   1 ? 
ATOM   1259 C CG   . LEU A 1 112 ? 15.478  -14.407 18.578  1     32.875 ? 280 LEU A CG   1 ? 
ATOM   1260 C CD1  . LEU A 1 112 ? 16.126  -13.171 19.226  1     31.089 ? 280 LEU A CD1  1 ? 
ATOM   1261 C CD2  . LEU A 1 112 ? 14.128  -14.63  19.109  1     31.24  ? 280 LEU A CD2  1 ? 
ATOM   1262 H H    . LEU A 1 112 ? 16.286  -16.393 15.946  1     25.311 ? 280 LEU A H    1 c 
ATOM   1263 H HA   . LEU A 1 112 ? 13.816  -15.357 16.677  1     25.137 ? 280 LEU A HA   1 c 
ATOM   1264 H HB2  . LEU A 1 112 ? 16.433  -14.279 16.769  1     28.245 ? 280 LEU A HB2  1 c 
ATOM   1265 H HB3  . LEU A 1 112 ? 15.213  -13.286 16.879  1     28.283 ? 280 LEU A HB3  1 c 
ATOM   1266 H HG   . LEU A 1 112 ? 16.033  -15.199 18.797  1     31.484 ? 280 LEU A HG   1 c 
ATOM   1267 H HD11 . LEU A 1 112 ? 16.963  -12.968 18.776  1     31.599 ? 280 LEU A HD11 1 c 
ATOM   1268 H HD12 . LEU A 1 112 ? 16.3    -13.35  20.166  1     31.6   ? 280 LEU A HD12 1 c 
ATOM   1269 H HD13 . LEU A 1 112 ? 15.526  -12.411 19.149  1     31.6   ? 280 LEU A HD13 1 c 
ATOM   1270 H HD21 . LEU A 1 112 ? 13.872  -15.558 18.971  1     31.605 ? 280 LEU A HD21 1 c 
ATOM   1271 H HD22 . LEU A 1 112 ? 13.498  -14.048 18.653  1     31.51  ? 280 LEU A HD22 1 c 
ATOM   1272 H HD23 . LEU A 1 112 ? 14.118  -14.432 20.06   1     31.551 ? 280 LEU A HD23 1 c 
ATOM   1273 N N    . LYS A 1 113 ? 14.939  -14.843 13.781  1     22.492 ? 281 LYS A N    1 ? 
ATOM   1274 C CA   . LYS A 1 113 ? 14.762  -14.102 12.527  1     23.262 ? 281 LYS A CA   1 ? 
ATOM   1275 C C    . LYS A 1 113 ? 13.539  -14.634 11.789  1     24.269 ? 281 LYS A C    1 ? 
ATOM   1276 O O    . LYS A 1 113 ? 13.225  -15.822 11.861  1     30.141 ? 281 LYS A O    1 ? 
ATOM   1277 C CB   . LYS A 1 113 ? 16.03   -14.187 11.673  1     24.259 ? 281 LYS A CB   1 ? 
ATOM   1278 C CG   . LYS A 1 113 ? 17.209  -13.557 12.338  1     22.917 ? 281 LYS A CG   1 ? 
ATOM   1279 C CD   . LYS A 1 113 ? 18.457  -13.8   11.515  1     22.988 ? 281 LYS A CD   1 ? 
ATOM   1280 C CE   . LYS A 1 113 ? 19.635  -13.16  12.164  1     24.613 ? 281 LYS A CE   1 ? 
ATOM   1281 N NZ   . LYS A 1 113 ? 20.841  -13.585 11.416  1     26.465 ? 281 LYS A NZ   1 ? 
ATOM   1282 H H    . LYS A 1 113 ? 15.48   -15.578 13.787  1     23.464 ? 281 LYS A H    1 c 
ATOM   1283 H HA   . LYS A 1 113 ? 14.612  -13.147 12.744  1     23.459 ? 281 LYS A HA   1 c 
ATOM   1284 H HB2  . LYS A 1 113 ? 16.234  -15.129 11.49   1     23.711 ? 281 LYS A HB2  1 c 
ATOM   1285 H HB3  . LYS A 1 113 ? 15.873  -13.739 10.817  1     23.713 ? 281 LYS A HB3  1 c 
ATOM   1286 H HG2  . LYS A 1 113 ? 17.054  -12.592 12.428  1     23.237 ? 281 LYS A HG2  1 c 
ATOM   1287 H HG3  . LYS A 1 113 ? 17.325  -13.944 13.233  1     23.233 ? 281 LYS A HG3  1 c 
ATOM   1288 H HD2  . LYS A 1 113 ? 18.613  -14.766 11.437  1     23.353 ? 281 LYS A HD2  1 c 
ATOM   1289 H HD3  . LYS A 1 113 ? 18.338  -13.43  10.615  1     23.334 ? 281 LYS A HD3  1 c 
ATOM   1290 H HE2  . LYS A 1 113 ? 19.555  -12.19  12.133  1     24.644 ? 281 LYS A HE2  1 c 
ATOM   1291 H HE3  . LYS A 1 113 ? 19.708  -13.444 13.092  1     24.644 ? 281 LYS A HE3  1 c 
ATOM   1292 H HZ1  . LYS A 1 113 ? 20.757  -13.366 10.54   1     25.854 ? 281 LYS A HZ1  1 c 
ATOM   1293 H HZ2  . LYS A 1 113 ? 20.952  -14.481 11.49   1     25.84  ? 281 LYS A HZ2  1 c 
ATOM   1294 H HZ3  . LYS A 1 113 ? 21.57   -13.169 11.755  1     25.867 ? 281 LYS A HZ3  1 c 
ATOM   1295 N N    . LEU A 1 114 ? 12.798  -13.729 11.137  1     20.607 ? 282 LEU A N    1 ? 
ATOM   1296 C CA   . LEU A 1 114 ? 11.586  -14.114 10.457  1     21.628 ? 282 LEU A CA   1 ? 
ATOM   1297 C C    . LEU A 1 114 ? 11.654  -13.785 8.966   1     25.79  ? 282 LEU A C    1 ? 
ATOM   1298 O O    . LEU A 1 114 ? 10.703  -14.08  8.25    1     28.764 ? 282 LEU A O    1 ? 
ATOM   1299 C CB   . LEU A 1 114 ? 10.403  -13.409 11.092  1     21.516 ? 282 LEU A CB   1 ? 
ATOM   1300 C CG   . LEU A 1 114 ? 10.008  -13.937 12.465  1     20.841 ? 282 LEU A CG   1 ? 
ATOM   1301 C CD1  . LEU A 1 114 ? 8.928   -13.018 13.03   1     20.033 ? 282 LEU A CD1  1 ? 
ATOM   1302 C CD2  . LEU A 1 114 ? 9.524   -15.375 12.343  1     22.041 ? 282 LEU A CD2  1 ? 
ATOM   1303 H H    . LEU A 1 114 ? 13.038  -12.847 11.154  1     21.707 ? 282 LEU A H    1 c 
ATOM   1304 H HA   . LEU A 1 114 ? 11.466  -15.09  10.543  1     22.166 ? 282 LEU A HA   1 c 
ATOM   1305 H HB2  . LEU A 1 114 ? 10.623  -12.452 11.176  1     21.39  ? 282 LEU A HB2  1 c 
ATOM   1306 H HB3  . LEU A 1 114 ? 9.627   -13.491 10.491  1     21.445 ? 282 LEU A HB3  1 c 
ATOM   1307 H HG   . LEU A 1 114 ? 10.802  -13.91  13.06   1     21.029 ? 282 LEU A HG   1 c 
ATOM   1308 H HD11 . LEU A 1 114 ? 9.297   -12.13  13.171  1     20.27  ? 282 LEU A HD11 1 c 
ATOM   1309 H HD12 . LEU A 1 114 ? 8.608   -13.373 13.877  1     20.277 ? 282 LEU A HD12 1 c 
ATOM   1310 H HD13 . LEU A 1 114 ? 8.189   -12.965 12.402  1     20.27  ? 282 LEU A HD13 1 c 
ATOM   1311 H HD21 . LEU A 1 114 ? 10.287  -15.976 12.338  1     21.678 ? 282 LEU A HD21 1 c 
ATOM   1312 H HD22 . LEU A 1 114 ? 9.021   -15.483 11.518  1     21.674 ? 282 LEU A HD22 1 c 
ATOM   1313 H HD23 . LEU A 1 114 ? 8.951   -15.589 13.099  1     21.66  ? 282 LEU A HD23 1 c 
ATOM   1314 N N    . GLY A 1 115 ? 12.745  -13.183 8.504   1     22.444 ? 283 GLY A N    1 ? 
ATOM   1315 C CA   . GLY A 1 115 ? 12.869  -12.948 7.079   1     23.695 ? 283 GLY A CA   1 ? 
ATOM   1316 C C    . GLY A 1 115 ? 13.296  -11.518 6.78    1     23.429 ? 283 GLY A C    1 ? 
ATOM   1317 O O    . GLY A 1 115 ? 13.17   -10.604 7.625   1     20.4   ? 283 GLY A O    1 ? 
ATOM   1318 H H    . GLY A 1 115 ? 13.417  -12.916 9.061   1     23.431 ? 283 GLY A H    1 c 
ATOM   1319 H HA2  . GLY A 1 115 ? 13.536  -13.575 6.725   1     23.373 ? 283 GLY A HA2  1 c 
ATOM   1320 H HA3  . GLY A 1 115 ? 12.012  -13.131 6.63    1     23.388 ? 283 GLY A HA3  1 c 
ATOM   1321 N N    . PRO A 1 116 ? 13.815  -11.305 5.545   1     26.012 ? 284 PRO A N    1 ? 
ATOM   1322 C CA   . PRO A 1 116 ? 14.263  -9.994  5.085   1     24.811 ? 284 PRO A CA   1 ? 
ATOM   1323 C C    . PRO A 1 116 ? 13.16   -8.955  5.066   1     22.759 ? 284 PRO A C    1 ? 
ATOM   1324 O O    . PRO A 1 116 ? 12.031  -9.224  4.669   1     23.525 ? 284 PRO A O    1 ? 
ATOM   1325 C CB   . PRO A 1 116 ? 14.77   -10.283 3.647   1     28.11  ? 284 PRO A CB   1 ? 
ATOM   1326 C CG   . PRO A 1 116 ? 15.111  -11.739 3.687   1     30.139 ? 284 PRO A CG   1 ? 
ATOM   1327 C CD   . PRO A 1 116 ? 13.982  -12.344 4.497   1     24.926 ? 284 PRO A CD   1 ? 
ATOM   1328 H HA   . PRO A 1 116 ? 15.012  -9.696  5.648   1     25.164 ? 284 PRO A HA   1 c 
ATOM   1329 H HB2  . PRO A 1 116 ? 14.069  -10.103 2.979   1     27.768 ? 284 PRO A HB2  1 c 
ATOM   1330 H HB3  . PRO A 1 116 ? 15.564  -9.739  3.437   1     27.819 ? 284 PRO A HB3  1 c 
ATOM   1331 H HG2  . PRO A 1 116 ? 15.138  -12.119 2.785   1     28.423 ? 284 PRO A HG2  1 c 
ATOM   1332 H HG3  . PRO A 1 116 ? 15.975  -11.888 4.123   1     28.433 ? 284 PRO A HG3  1 c 
ATOM   1333 H HD2  . PRO A 1 116 ? 13.168  -12.449 3.957   1     26.258 ? 284 PRO A HD2  1 c 
ATOM   1334 H HD3  . PRO A 1 116 ? 14.249  -13.211 4.871   1     26.229 ? 284 PRO A HD3  1 c 
ATOM   1335 N N    . VAL A 1 117 ? 13.521  -7.733  5.475   1     22.099 ? 285 VAL A N    1 ? 
ATOM   1336 C CA   . VAL A 1 117 ? 12.586  -6.648  5.552   1     23.67  ? 285 VAL A CA   1 ? 
ATOM   1337 C C    . VAL A 1 117 ? 12.321  -6.177  4.134   1     28.58  ? 285 VAL A C    1 ? 
ATOM   1338 O O    . VAL A 1 117 ? 11.158  -6.072  3.752   1     36.788 ? 285 VAL A O    1 ? 
ATOM   1339 C CB   . VAL A 1 117 ? 13.087  -5.509  6.464   1     23.67  ? 285 VAL A CB   1 ? 
ATOM   1340 C CG1  . VAL A 1 117 ? 12.263  -4.245  6.262   1     24.416 ? 285 VAL A CG1  1 ? 
ATOM   1341 C CG2  . VAL A 1 117 ? 13.143  -5.981  7.916   1     26.051 ? 285 VAL A CG2  1 ? 
ATOM   1342 H H    . VAL A 1 117 ? 14.391  -7.578  5.709   1     22.66  ? 285 VAL A H    1 c 
ATOM   1343 H HA   . VAL A 1 117 ? 11.753  -6.988  5.924   1     24.214 ? 285 VAL A HA   1 c 
ATOM   1344 H HB   . VAL A 1 117 ? 14.011  -5.304  6.186   1     24.226 ? 285 VAL A HB   1 c 
ATOM   1345 H HG11 . VAL A 1 117 ? 11.334  -4.48   6.094   1     24.244 ? 285 VAL A HG11 1 c 
ATOM   1346 H HG12 . VAL A 1 117 ? 12.612  -3.743  5.508   1     24.323 ? 285 VAL A HG12 1 c 
ATOM   1347 H HG13 . VAL A 1 117 ? 12.313  -3.695  7.063   1     24.244 ? 285 VAL A HG13 1 c 
ATOM   1348 H HG21 . VAL A 1 117 ? 13.428  -5.247  8.486   1     25.315 ? 285 VAL A HG21 1 c 
ATOM   1349 H HG22 . VAL A 1 117 ? 13.775  -6.715  7.996   1     25.307 ? 285 VAL A HG22 1 c 
ATOM   1350 H HG23 . VAL A 1 117 ? 12.261  -6.282  8.194   1     25.321 ? 285 VAL A HG23 1 c 
ATOM   1351 N N    . SER A 1 118 ? 13.391  -5.928  3.374   1     27.54  ? 286 SER A N    1 ? 
ATOM   1352 C CA   . SER A 1 118 ? 13.207  -5.381  2.04    1     36.757 ? 286 SER A CA   1 ? 
ATOM   1353 C C    . SER A 1 118 ? 13.965  -6.213  1.007   1     37.051 ? 286 SER A C    1 ? 
ATOM   1354 O O    . SER A 1 118 ? 14.594  -5.64   0.127   1     42.409 ? 286 SER A O    1 ? 
ATOM   1355 C CB   . SER A 1 118 ? 13.631  -3.923  2.031   1     39.422 ? 286 SER A CB   1 ? 
ATOM   1356 O OG   . SER A 1 118 ? 12.855  -3.187  2.973   1     47.857 ? 286 SER A OG   1 ? 
ATOM   1357 H H    . SER A 1 118 ? 14.236  -6.086  3.684   1     29.549 ? 286 SER A H    1 c 
ATOM   1358 H HA   . SER A 1 118 ? 12.245  -5.421  1.81    1     35.213 ? 286 SER A HA   1 c 
ATOM   1359 H HB2  . SER A 1 118 ? 14.577  -3.856  2.26    1     40.652 ? 286 SER A HB2  1 c 
ATOM   1360 H HB3  . SER A 1 118 ? 13.5    -3.549  1.139   1     40.66  ? 286 SER A HB3  1 c 
ATOM   1361 N N    . GLY A 1 119 ? 13.919  -7.551  1.144   1     32.067 ? 287 GLY A N    1 ? 
ATOM   1362 C CA   . GLY A 1 119 ? 14.645  -8.454  0.254   1     32.061 ? 287 GLY A CA   1 ? 
ATOM   1363 C C    . GLY A 1 119 ? 16.093  -8.719  0.696   1     33.917 ? 287 GLY A C    1 ? 
ATOM   1364 O O    . GLY A 1 119 ? 16.627  -9.777  0.406   1     34.714 ? 287 GLY A O    1 ? 
ATOM   1365 H H    . GLY A 1 119 ? 13.407  -7.915  1.808   1     33.172 ? 287 GLY A H    1 c 
ATOM   1366 H HA2  . GLY A 1 119 ? 14.164  -9.31   0.221   1     32.48  ? 287 GLY A HA2  1 c 
ATOM   1367 H HA3  . GLY A 1 119 ? 14.646  -8.077  -0.657  1     32.538 ? 287 GLY A HA3  1 c 
ATOM   1368 N N    . TRP A 1 120 ? 16.719  -7.809  1.454   1     36.065 ? 288 TRP A N    1 ? 
ATOM   1369 C CA   . TRP A 1 120 ? 18.126  -7.976  1.809   1     41.471 ? 288 TRP A CA   1 ? 
ATOM   1370 C C    . TRP A 1 120 ? 18.25   -8.724  3.14    1     35.97  ? 288 TRP A C    1 ? 
ATOM   1371 O O    . TRP A 1 120 ? 17.773  -8.216  4.15    1     31.35  ? 288 TRP A O    1 ? 
ATOM   1372 C CB   . TRP A 1 120 ? 18.782  -6.593  1.886   1     47.011 ? 288 TRP A CB   1 ? 
ATOM   1373 C CG   . TRP A 1 120 ? 20.253  -6.592  2.22    1     51.471 ? 288 TRP A CG   1 ? 
ATOM   1374 C CD1  . TRP A 1 120 ? 21.185  -7.557  1.956   1     48.931 ? 288 TRP A CD1  1 ? 
ATOM   1375 C CD2  . TRP A 1 120 ? 20.963  -5.52   2.884   1     53.138 ? 288 TRP A CD2  1 ? 
ATOM   1376 N NE1  . TRP A 1 120 ? 22.421  -7.164  2.403   1     51.799 ? 288 TRP A NE1  1 ? 
ATOM   1377 C CE2  . TRP A 1 120 ? 22.318  -5.917  2.973   1     54.707 ? 288 TRP A CE2  1 ? 
ATOM   1378 C CE3  . TRP A 1 120 ? 20.587  -4.271  3.398   1     53.706 ? 288 TRP A CE3  1 ? 
ATOM   1379 C CZ2  . TRP A 1 120 ? 23.288  -5.11   3.568   1     53.702 ? 288 TRP A CZ2  1 ? 
ATOM   1380 C CZ3  . TRP A 1 120 ? 21.551  -3.474  3.98    1     55.566 ? 288 TRP A CZ3  1 ? 
ATOM   1381 C CH2  . TRP A 1 120 ? 22.883  -3.888  4.061   1     50.725 ? 288 TRP A CH2  1 ? 
ATOM   1382 H H    . TRP A 1 120 ? 16.272  -7.076  1.764   1     36.703 ? 288 TRP A H    1 c 
ATOM   1383 H HA   . TRP A 1 120 ? 18.579  -8.489  1.094   1     40.163 ? 288 TRP A HA   1 c 
ATOM   1384 H HB2  . TRP A 1 120 ? 18.656  -6.144  1.023   1     46.64  ? 288 TRP A HB2  1 c 
ATOM   1385 H HB3  . TRP A 1 120 ? 18.308  -6.061  2.56    1     46.568 ? 288 TRP A HB3  1 c 
ATOM   1386 H HD1  . TRP A 1 120 ? 21.015  -8.371  1.518   1     49.955 ? 288 TRP A HD1  1 c 
ATOM   1387 H HE1  . TRP A 1 120 ? 23.155  -7.631  2.335   1     51.763 ? 288 TRP A HE1  1 c 
ATOM   1388 H HE3  . TRP A 1 120 ? 19.691  -3.984  3.348   1     53.966 ? 288 TRP A HE3  1 c 
ATOM   1389 H HZ2  . TRP A 1 120 ? 24.187  -5.385  3.619   1     53.181 ? 288 TRP A HZ2  1 c 
ATOM   1390 H HZ3  . TRP A 1 120 ? 21.307  -2.634  4.331   1     53.953 ? 288 TRP A HZ3  1 c 
ATOM   1391 H HH2  . TRP A 1 120 ? 23.517  -3.322  4.465   1     52.533 ? 288 TRP A HH2  1 c 
ATOM   1392 N N    . PRO A 1 121 ? 18.887  -9.921  3.206   1     33.151 ? 289 PRO A N    1 ? 
ATOM   1393 C CA   . PRO A 1 121 ? 18.894  -10.707 4.446   1     33.153 ? 289 PRO A CA   1 ? 
ATOM   1394 C C    . PRO A 1 121 ? 19.659  -10.111 5.624   1     31.337 ? 289 PRO A C    1 ? 
ATOM   1395 O O    . PRO A 1 121 ? 19.6    -10.668 6.716   1     34.174 ? 289 PRO A O    1 ? 
ATOM   1396 C CB   . PRO A 1 121 ? 19.481  -12.083 4.028   1     36.981 ? 289 PRO A CB   1 ? 
ATOM   1397 C CG   . PRO A 1 121 ? 19.287  -12.112 2.524   1     37.365 ? 289 PRO A CG   1 ? 
ATOM   1398 C CD   . PRO A 1 121 ? 19.529  -10.661 2.093   1     36.526 ? 289 PRO A CD   1 ? 
ATOM   1399 H HA   . PRO A 1 121 ? 17.952  -10.838 4.717   1     33.415 ? 289 PRO A HA   1 c 
ATOM   1400 H HB2  . PRO A 1 121 ? 20.437  -12.148 4.262   1     36.159 ? 289 PRO A HB2  1 c 
ATOM   1401 H HB3  . PRO A 1 121 ? 18.992  -12.822 4.462   1     36.182 ? 289 PRO A HB3  1 c 
ATOM   1402 H HG2  . PRO A 1 121 ? 19.927  -12.718 2.1     1     37.089 ? 289 PRO A HG2  1 c 
ATOM   1403 H HG3  . PRO A 1 121 ? 18.378  -12.397 2.293   1     37.089 ? 289 PRO A HG3  1 c 
ATOM   1404 H HD2  . PRO A 1 121 ? 20.49   -10.465 2.036   1     36.001 ? 289 PRO A HD2  1 c 
ATOM   1405 H HD3  . PRO A 1 121 ? 19.1    -10.475 1.232   1     35.974 ? 289 PRO A HD3  1 c 
ATOM   1406 N N    . ASP A 1 122 ? 20.345  -8.989  5.394   1     29.64  ? 290 ASP A N    1 ? 
ATOM   1407 C CA   . ASP A 1 122 ? 21.065  -8.289  6.452   1     29.383 ? 290 ASP A CA   1 ? 
ATOM   1408 C C    . ASP A 1 122 ? 20.126  -7.407  7.265   1     26.905 ? 290 ASP A C    1 ? 
ATOM   1409 O O    . ASP A 1 122 ? 20.604  -6.686  8.135   1     28.134 ? 290 ASP A O    1 ? 
ATOM   1410 C CB   . ASP A 1 122 ? 22.192  -7.427  5.899   1     31.721 ? 290 ASP A CB   1 ? 
ATOM   1411 C CG   . ASP A 1 122 ? 23.494  -8.153  5.605   1     38.845 ? 290 ASP A CG   1 ? 
ATOM   1412 O OD1  . ASP A 1 122 ? 23.548  -9.385  5.852   1     39.932 ? 290 ASP A OD1  1 ? 
ATOM   1413 O OD2  . ASP A 1 122 ? 24.462  -7.458  5.201   1     47.564 ? 290 ASP A OD2  1 ? 
ATOM   1414 H H    . ASP A 1 122 ? 20.403  -8.661  4.545   1     30.089 ? 290 ASP A H    1 c 
ATOM   1415 H HA   . ASP A 1 122 ? 21.458  -8.957  7.058   1     29.499 ? 290 ASP A HA   1 c 
ATOM   1416 H HB2  . ASP A 1 122 ? 21.868  -7.022  5.077   1     32.957 ? 290 ASP A HB2  1 c 
ATOM   1417 H HB3  . ASP A 1 122 ? 22.407  -6.701  6.519   1     32.685 ? 290 ASP A HB3  1 c 
ATOM   1418 N N    . GLU A 1 123 ? 18.835  -7.37   6.913   1     24.626 ? 291 GLU A N    1 ? 
ATOM   1419 C CA   . GLU A 1 123 ? 17.843  -6.66   7.712   1     25.139 ? 291 GLU A CA   1 ? 
ATOM   1420 C C    . GLU A 1 123 ? 16.672  -7.618  7.883   1     22.322 ? 291 GLU A C    1 ? 
ATOM   1421 O O    . GLU A 1 123 ? 16.07   -8.037  6.887   1     24.656 ? 291 GLU A O    1 ? 
ATOM   1422 C CB   . GLU A 1 123 ? 17.348  -5.389  7.019   1     25.207 ? 291 GLU A CB   1 ? 
ATOM   1423 C CG   . GLU A 1 123 ? 18.49   -4.442  6.639   1     32.469 ? 291 GLU A CG   1 ? 
ATOM   1424 C CD   . GLU A 1 123 ? 18.065  -3.27   5.766   1     39.388 ? 291 GLU A CD   1 ? 
ATOM   1425 O OE1  . GLU A 1 123 ? 17.235  -3.497  4.848   1     46.503 ? 291 GLU A OE1  1 ? 
ATOM   1426 O OE2  . GLU A 1 123 ? 18.606  -2.178  5.965   1     41.741 ? 291 GLU A OE2  1 ? 
ATOM   1427 H H    . GLU A 1 123 ? 18.562  -7.762  6.135   1     25.339 ? 291 GLU A H    1 c 
ATOM   1428 H HA   . GLU A 1 123 ? 18.228  -6.437  8.594   1     24.457 ? 291 GLU A HA   1 c 
ATOM   1429 H HB2  . GLU A 1 123 ? 16.851  -5.639  6.217   1     26.767 ? 291 GLU A HB2  1 c 
ATOM   1430 H HB3  . GLU A 1 123 ? 16.732  -4.922  7.62    1     26.701 ? 291 GLU A HB3  1 c 
ATOM   1431 H HG2  . GLU A 1 123 ? 18.903  -4.091  7.452   1     32.024 ? 291 GLU A HG2  1 c 
ATOM   1432 H HG3  . GLU A 1 123 ? 19.178  -4.946  6.156   1     31.979 ? 291 GLU A HG3  1 c 
ATOM   1433 N N    . GLN A 1 124 ? 16.461  -8.048  9.116   1     19.388 ? 292 GLN A N    1 ? 
ATOM   1434 C CA   . GLN A 1 124 ? 15.53   -9.117  9.4     1     19.102 ? 292 GLN A CA   1 ? 
ATOM   1435 C C    . GLN A 1 124 ? 14.461  -8.642  10.383  1     19.278 ? 292 GLN A C    1 ? 
ATOM   1436 O O    . GLN A 1 124 ? 14.757  -7.981  11.378  1     19.59  ? 292 GLN A O    1 ? 
ATOM   1437 C CB   . GLN A 1 124 ? 16.262  -10.281 10.045  1     20.061 ? 292 GLN A CB   1 ? 
ATOM   1438 C CG   . GLN A 1 124 ? 17.302  -10.97  9.166   1     22.612 ? 292 GLN A CG   1 ? 
ATOM   1439 C CD   . GLN A 1 124 ? 16.669  -11.977 8.231   1     24.045 ? 292 GLN A CD   1 ? 
ATOM   1440 O OE1  . GLN A 1 124 ? 15.671  -12.607 8.575   1     23.653 ? 292 GLN A OE1  1 ? 
ATOM   1441 N NE2  . GLN A 1 124 ? 17.246  -12.138 7.054   1     26.41  ? 292 GLN A NE2  1 ? 
ATOM   1442 H H    . GLN A 1 124 ? 16.908  -7.66   9.813   1     20.051 ? 292 GLN A H    1 c 
ATOM   1443 H HA   . GLN A 1 124 ? 15.106  -9.415  8.561   1     19.405 ? 292 GLN A HA   1 c 
ATOM   1444 H HB2  . GLN A 1 124 ? 16.71   -9.946  10.849  1     20.384 ? 292 GLN A HB2  1 c 
ATOM   1445 H HB3  . GLN A 1 124 ? 15.6    -10.942 10.336  1     20.413 ? 292 GLN A HB3  1 c 
ATOM   1446 H HG2  . GLN A 1 124 ? 17.778  -10.297 8.635   1     22.378 ? 292 GLN A HG2  1 c 
ATOM   1447 H HG3  . GLN A 1 124 ? 17.959  -11.423 9.733   1     22.338 ? 292 GLN A HG3  1 c 
ATOM   1448 H HE21 . GLN A 1 124 ? 16.75   -12.18  6.321   1     25.686 ? 292 GLN A HE21 1 c 
ATOM   1449 H HE22 . GLN A 1 124 ? 18.129  -12.206 7       1     25.69  ? 292 GLN A HE22 1 c 
ATOM   1450 N N    . TYR A 1 125 ? 13.22   -8.976  10.077  1     18.819 ? 293 TYR A N    1 ? 
ATOM   1451 C CA   . TYR A 1 125 ? 12.17   -8.981  11.07   1     18.023 ? 293 TYR A CA   1 ? 
ATOM   1452 C C    . TYR A 1 125 ? 12.542  -9.999  12.139  1     18.946 ? 293 TYR A C    1 ? 
ATOM   1453 O O    . TYR A 1 125 ? 13.214  -10.97  11.854  1     17.879 ? 293 TYR A O    1 ? 
ATOM   1454 C CB   . TYR A 1 125 ? 10.844  -9.429  10.46   1     17.581 ? 293 TYR A CB   1 ? 
ATOM   1455 C CG   . TYR A 1 125 ? 10.297  -8.482  9.407   1     18.072 ? 293 TYR A CG   1 ? 
ATOM   1456 C CD1  . TYR A 1 125 ? 9.855   -7.212  9.738   1     16.648 ? 293 TYR A CD1  1 ? 
ATOM   1457 C CD2  . TYR A 1 125 ? 10.164  -8.909  8.086   1     18.594 ? 293 TYR A CD2  1 ? 
ATOM   1458 C CE1  . TYR A 1 125 ? 9.322   -6.371  8.775   1     18.423 ? 293 TYR A CE1  1 ? 
ATOM   1459 C CE2  . TYR A 1 125 ? 9.624   -8.082  7.12    1     19.097 ? 293 TYR A CE2  1 ? 
ATOM   1460 C CZ   . TYR A 1 125 ? 9.166   -6.824  7.466   1     19.307 ? 293 TYR A CZ   1 ? 
ATOM   1461 O OH   . TYR A 1 125 ? 8.627   -5.982  6.49    1     20.651 ? 293 TYR A OH   1 ? 
ATOM   1462 H H    . TYR A 1 125 ? 13.015  -9.21   9.218   1     18.739 ? 293 TYR A H    1 c 
ATOM   1463 H HA   . TYR A 1 125 ? 12.076  -8.076  11.47   1     18.255 ? 293 TYR A HA   1 c 
ATOM   1464 H HB2  . TYR A 1 125 ? 10.969  -10.318 10.059  1     17.809 ? 293 TYR A HB2  1 c 
ATOM   1465 H HB3  . TYR A 1 125 ? 10.182  -9.516  11.182  1     17.802 ? 293 TYR A HB3  1 c 
ATOM   1466 H HD1  . TYR A 1 125 ? 9.927   -6.912  10.63   1     17.418 ? 293 TYR A HD1  1 c 
ATOM   1467 H HD2  . TYR A 1 125 ? 10.44   -9.78   7.847   1     18.574 ? 293 TYR A HD2  1 c 
ATOM   1468 H HE1  . TYR A 1 125 ? 9.017   -5.512  9.014   1     18.239 ? 293 TYR A HE1  1 c 
ATOM   1469 H HE2  . TYR A 1 125 ? 9.534   -8.388  6.236   1     19.108 ? 293 TYR A HE2  1 c 
ATOM   1470 N N    . VAL A 1 126 ? 12.129  -9.741  13.372  1     16.292 ? 294 VAL A N    1 ? 
ATOM   1471 C CA   . VAL A 1 126 ? 12.422  -10.638 14.48   1     16.474 ? 294 VAL A CA   1 ? 
ATOM   1472 C C    . VAL A 1 126 ? 11.157  -11.026 15.234  1     17.064 ? 294 VAL A C    1 ? 
ATOM   1473 O O    . VAL A 1 126 ? 10.123  -10.364 15.156  1     15.933 ? 294 VAL A O    1 ? 
ATOM   1474 C CB   . VAL A 1 126 ? 13.457  -9.99   15.429  1     19.403 ? 294 VAL A CB   1 ? 
ATOM   1475 C CG1  . VAL A 1 126 ? 14.756  -9.676  14.715  1     20.303 ? 294 VAL A CG1  1 ? 
ATOM   1476 C CG2  . VAL A 1 126 ? 12.892  -8.757  16.154  1     20.48  ? 294 VAL A CG2  1 ? 
ATOM   1477 H H    . VAL A 1 126 ? 11.634  -8.99   13.533  1     16.974 ? 294 VAL A H    1 c 
ATOM   1478 H HA   . VAL A 1 126 ? 12.814  -11.447 14.116  1     17.104 ? 294 VAL A HA   1 c 
ATOM   1479 H HB   . VAL A 1 126 ? 13.664  -10.661 16.122  1     19.177 ? 294 VAL A HB   1 c 
ATOM   1480 H HG11 . VAL A 1 126 ? 14.624  -8.923  14.115  1     20.01  ? 294 VAL A HG11 1 c 
ATOM   1481 H HG12 . VAL A 1 126 ? 15.04   -10.451 14.201  1     20.027 ? 294 VAL A HG12 1 c 
ATOM   1482 H HG13 . VAL A 1 126 ? 15.44   -9.453  15.368  1     20.027 ? 294 VAL A HG13 1 c 
ATOM   1483 H HG21 . VAL A 1 126 ? 13.617  -8.149  16.372  1     20.062 ? 294 VAL A HG21 1 c 
ATOM   1484 H HG22 . VAL A 1 126 ? 12.45   -9.038  16.974  1     20.107 ? 294 VAL A HG22 1 c 
ATOM   1485 H HG23 . VAL A 1 126 ? 12.252  -8.304  15.583  1     20.055 ? 294 VAL A HG23 1 c 
ATOM   1486 N N    . LYS A 1 127 ? 11.282  -12.129 15.976  1     16.978 ? 295 LYS A N    1 ? 
ATOM   1487 C CA   . LYS A 1 127 ? 10.269  -12.577 16.895  1     17.115 ? 295 LYS A CA   1 ? 
ATOM   1488 C C    . LYS A 1 127 ? 10.328  -11.659 18.111  1     16.625 ? 295 LYS A C    1 ? 
ATOM   1489 O O    . LYS A 1 127 ? 10.879  -12.007 19.132  1     18.654 ? 295 LYS A O    1 ? 
ATOM   1490 C CB   . LYS A 1 127 ? 10.529  -14.028 17.307  1     19.981 ? 295 LYS A CB   1 ? 
ATOM   1491 C CG   . LYS A 1 127 ? 10.439  -15.033 16.14   1     21.527 ? 295 LYS A CG   1 ? 
ATOM   1492 C CD   . LYS A 1 127 ? 10.542  -16.482 16.62   1     23.448 ? 295 LYS A CD   1 ? 
ATOM   1493 C CE   . LYS A 1 127 ? 10.507  -17.436 15.416  1     25.438 ? 295 LYS A CE   1 ? 
ATOM   1494 N NZ   . LYS A 1 127 ? 10.865  -18.783 15.841  1     29.021 ? 295 LYS A NZ   1 ? 
ATOM   1495 H H    . LYS A 1 127 ? 12.047  -12.624 15.902  1     17.045 ? 295 LYS A H    1 c 
ATOM   1496 H HA   . LYS A 1 127 ? 9.381   -12.505 16.461  1     17.464 ? 295 LYS A HA   1 c 
ATOM   1497 H HB2  . LYS A 1 127 ? 11.423  -14.092 17.703  1     19.68  ? 295 LYS A HB2  1 c 
ATOM   1498 H HB3  . LYS A 1 127 ? 9.877   -14.285 17.993  1     19.628 ? 295 LYS A HB3  1 c 
ATOM   1499 H HG2  . LYS A 1 127 ? 9.584   -14.905 15.675  1     21.583 ? 295 LYS A HG2  1 c 
ATOM   1500 H HG3  . LYS A 1 127 ? 11.165  -14.849 15.505  1     21.583 ? 295 LYS A HG3  1 c 
ATOM   1501 H HD2  . LYS A 1 127 ? 11.38   -16.607 17.114  1     23.499 ? 295 LYS A HD2  1 c 
ATOM   1502 H HD3  . LYS A 1 127 ? 9.789   -16.684 17.218  1     23.439 ? 295 LYS A HD3  1 c 
ATOM   1503 H HE2  . LYS A 1 127 ? 9.613   -17.448 15.03   1     25.798 ? 295 LYS A HE2  1 c 
ATOM   1504 H HE3  . LYS A 1 127 ? 11.134  -17.133 14.735  1     25.859 ? 295 LYS A HE3  1 c 
ATOM   1505 H HZ1  . LYS A 1 127 ? 10.293  -19.063 16.485  1     27.832 ? 295 LYS A HZ1  1 c 
ATOM   1506 H HZ2  . LYS A 1 127 ? 11.709  -18.786 16.17   1     27.829 ? 295 LYS A HZ2  1 c 
ATOM   1507 H HZ3  . LYS A 1 127 ? 10.819  -19.349 15.135  1     27.853 ? 295 LYS A HZ3  1 c 
ATOM   1508 N N    . TYR A 1 128 ? 9.633   -10.548 18.006  1     16.681 ? 296 TYR A N    1 ? 
ATOM   1509 C CA   . TYR A 1 128 ? 9.766   -9.448  18.961  1     15.715 ? 296 TYR A CA   1 ? 
ATOM   1510 C C    . TYR A 1 128 ? 9.127   -9.788  20.306  1     16.926 ? 296 TYR A C    1 ? 
ATOM   1511 O O    . TYR A 1 128 ? 9.317   -9.038  21.26   1     18.164 ? 296 TYR A O    1 ? 
ATOM   1512 C CB   . TYR A 1 128 ? 9.178   -8.181  18.359  1     15.849 ? 296 TYR A CB   1 ? 
ATOM   1513 C CG   . TYR A 1 128 ? 7.75    -8.345  17.862  1     17.402 ? 296 TYR A CG   1 ? 
ATOM   1514 C CD1  . TYR A 1 128 ? 6.686   -8.313  18.767  1     18.225 ? 296 TYR A CD1  1 ? 
ATOM   1515 C CD2  . TYR A 1 128 ? 7.467   -8.611  16.523  1     16.664 ? 296 TYR A CD2  1 ? 
ATOM   1516 C CE1  . TYR A 1 128 ? 5.388   -8.499  18.333  1     16.565 ? 296 TYR A CE1  1 ? 
ATOM   1517 C CE2  . TYR A 1 128 ? 6.164   -8.827  16.081  1     16.203 ? 296 TYR A CE2  1 ? 
ATOM   1518 C CZ   . TYR A 1 128 ? 5.13    -8.794  16.997  1     17.423 ? 296 TYR A CZ   1 ? 
ATOM   1519 O OH   . TYR A 1 128 ? 3.859   -9.002  16.53   1     15.934 ? 296 TYR A OH   1 ? 
ATOM   1520 H H    . TYR A 1 128 ? 9.052   -10.46  17.307  1     16.463 ? 296 TYR A H    1 c 
ATOM   1521 H HA   . TYR A 1 128 ? 10.733  -9.296  19.111  1     16.149 ? 296 TYR A HA   1 c 
ATOM   1522 H HB2  . TYR A 1 128 ? 9.2     -7.472  19.038  1     16.166 ? 296 TYR A HB2  1 c 
ATOM   1523 H HB3  . TYR A 1 128 ? 9.747   -7.9    17.608  1     16.16  ? 296 TYR A HB3  1 c 
ATOM   1524 H HD1  . TYR A 1 128 ? 6.852   -8.142  19.681  1     17.598 ? 296 TYR A HD1  1 c 
ATOM   1525 H HD2  . TYR A 1 128 ? 8.177   -8.666  15.904  1     16.721 ? 296 TYR A HD2  1 c 
ATOM   1526 H HE1  . TYR A 1 128 ? 4.682   -8.484  18.951  1     17.121 ? 296 TYR A HE1  1 c 
ATOM   1527 H HE2  . TYR A 1 128 ? 5.99    -9.008  15.173  1     16.608 ? 296 TYR A HE2  1 c 
ATOM   1528 N N    . TRP A 1 129 ? 8.339   -10.852 20.363  1     19.029 ? 297 TRP A N    1 ? 
ATOM   1529 C CA   . TRP A 1 129 ? 7.669   -11.315 21.571  1     18.504 ? 297 TRP A CA   1 ? 
ATOM   1530 C C    . TRP A 1 129 ? 8.548   -12.303 22.331  1     19.63  ? 297 TRP A C    1 ? 
ATOM   1531 O O    . TRP A 1 129 ? 8.192   -12.745 23.426  1     20.799 ? 297 TRP A O    1 ? 
ATOM   1532 C CB   . TRP A 1 129 ? 6.328   -11.965 21.22   1     17.913 ? 297 TRP A CB   1 ? 
ATOM   1533 C CG   . TRP A 1 129 ? 6.517   -13.159 20.34   1     19.166 ? 297 TRP A CG   1 ? 
ATOM   1534 C CD1  . TRP A 1 129 ? 6.772   -14.431 20.747  1     19.818 ? 297 TRP A CD1  1 ? 
ATOM   1535 C CD2  . TRP A 1 129 ? 6.527   -13.189 18.891  1     19.168 ? 297 TRP A CD2  1 ? 
ATOM   1536 N NE1  . TRP A 1 129 ? 6.895   -15.264 19.674  1     20.916 ? 297 TRP A NE1  1 ? 
ATOM   1537 C CE2  . TRP A 1 129 ? 6.766   -14.537 18.525  1     21.017 ? 297 TRP A CE2  1 ? 
ATOM   1538 C CE3  . TRP A 1 129 ? 6.354   -12.231 17.874  1     19.178 ? 297 TRP A CE3  1 ? 
ATOM   1539 C CZ2  . TRP A 1 129 ? 6.862   -14.945 17.199  1     18.922 ? 297 TRP A CZ2  1 ? 
ATOM   1540 C CZ3  . TRP A 1 129 ? 6.405   -12.645 16.565  1     19.807 ? 297 TRP A CZ3  1 ? 
ATOM   1541 C CH2  . TRP A 1 129 ? 6.688   -13.966 16.234  1     19.62  ? 297 TRP A CH2  1 ? 
ATOM   1542 H H    . TRP A 1 129 ? 8.195   -11.317 19.594  1     18.361 ? 297 TRP A H    1 c 
ATOM   1543 H HA   . TRP A 1 129 ? 7.491   -10.531 22.158  1     18.682 ? 297 TRP A HA   1 c 
ATOM   1544 H HB2  . TRP A 1 129 ? 5.882   -12.242 22.049  1     18.327 ? 297 TRP A HB2  1 c 
ATOM   1545 H HB3  . TRP A 1 129 ? 5.771   -11.306 20.753  1     18.32  ? 297 TRP A HB3  1 c 
ATOM   1546 H HD1  . TRP A 1 129 ? 6.812   -14.713 21.647  1     19.904 ? 297 TRP A HD1  1 c 
ATOM   1547 H HE1  . TRP A 1 129 ? 7.061   -16.119 19.717  1     20.636 ? 297 TRP A HE1  1 c 
ATOM   1548 H HE3  . TRP A 1 129 ? 6.178   -11.331 18.089  1     19.333 ? 297 TRP A HE3  1 c 
ATOM   1549 H HZ2  . TRP A 1 129 ? 7.022   -15.845 16.97   1     19.55  ? 297 TRP A HZ2  1 c 
ATOM   1550 H HZ3  . TRP A 1 129 ? 6.312   -12.008 15.876  1     19.612 ? 297 TRP A HZ3  1 c 
ATOM   1551 H HH2  . TRP A 1 129 ? 6.724   -14.212 15.326  1     19.504 ? 297 TRP A HH2  1 c 
ATOM   1552 N N    . ASP A 1 130 ? 9.648   -12.725 21.715  1     18.738 ? 298 ASP A N    1 ? 
ATOM   1553 C CA   . ASP A 1 130 ? 10.475  -13.773 22.284  1     20.107 ? 298 ASP A CA   1 ? 
ATOM   1554 C C    . ASP A 1 130 ? 11.324  -13.172 23.396  1     17.937 ? 298 ASP A C    1 ? 
ATOM   1555 O O    . ASP A 1 130 ? 11.833  -12.109 23.255  1     17.94  ? 298 ASP A O    1 ? 
ATOM   1556 C CB   . ASP A 1 130 ? 11.392  -14.382 21.24   1     21.962 ? 298 ASP A CB   1 ? 
ATOM   1557 C CG   . ASP A 1 130 ? 12.099  -15.661 21.658  1     24.13  ? 298 ASP A CG   1 ? 
ATOM   1558 O OD1  . ASP A 1 130 ? 13.018  -15.567 22.491  1     23.27  ? 298 ASP A OD1  1 ? 
ATOM   1559 O OD2  . ASP A 1 130 ? 11.787  -16.717 21.072  1     23.396 ? 298 ASP A OD2  1 ? 
ATOM   1560 H H    . ASP A 1 130 ? 9.897   -12.362 20.915  1     19.227 ? 298 ASP A H    1 c 
ATOM   1561 H HA   . ASP A 1 130 ? 9.892   -14.477 22.65   1     19.735 ? 298 ASP A HA   1 c 
ATOM   1562 H HB2  . ASP A 1 130 ? 10.861  -14.574 20.438  1     22.006 ? 298 ASP A HB2  1 c 
ATOM   1563 H HB3  . ASP A 1 130 ? 12.073  -13.722 20.994  1     22.023 ? 298 ASP A HB3  1 c 
ATOM   1564 N N    A GLU A 1 131 ? 11.489  -13.903 24.493  0.5   18.344 ? 299 GLU A N    1 ? 
ATOM   1565 N N    B GLU A 1 131 ? 11.49   -13.901 24.494  0.5   19.818 ? 299 GLU A N    1 ? 
ATOM   1566 C CA   A GLU A 1 131 ? 12.212  -13.387 25.639  0.5   17.589 ? 299 GLU A CA   1 ? 
ATOM   1567 C CA   B GLU A 1 131 ? 12.212  -13.389 25.644  0.5   20.131 ? 299 GLU A CA   1 ? 
ATOM   1568 C C    A GLU A 1 131 ? 13.659  -13.06  25.257  0.5   18.964 ? 299 GLU A C    1 ? 
ATOM   1569 C C    B GLU A 1 131 ? 13.662  -13.066 25.263  0.5   20.462 ? 299 GLU A C    1 ? 
ATOM   1570 O O    A GLU A 1 131 ? 14.262  -12.166 25.853  0.5   19.45  ? 299 GLU A O    1 ? 
ATOM   1571 O O    B GLU A 1 131 ? 14.264  -12.17  25.856  0.5   20.874 ? 299 GLU A O    1 ? 
ATOM   1572 C CB   A GLU A 1 131 ? 12.15   -14.343 26.832  0.5   18.384 ? 299 GLU A CB   1 ? 
ATOM   1573 C CB   B GLU A 1 131 ? 12.026  -14.373 26.802  0.5   23.062 ? 299 GLU A CB   1 ? 
ATOM   1574 C CG   A GLU A 1 131 ? 12.741  -13.7   28.086  0.5   17.333 ? 299 GLU A CG   1 ? 
ATOM   1575 C CG   B GLU A 1 131 ? 10.567  -14.489 27.243  0.5   24.055 ? 299 GLU A CG   1 ? 
ATOM   1576 C CD   A GLU A 1 131 ? 11.995  -12.496 28.634  0.5   16.38  ? 299 GLU A CD   1 ? 
ATOM   1577 C CD   B GLU A 1 131 ? 9.95    -13.38  28.089  0.5   26.469 ? 299 GLU A CD   1 ? 
ATOM   1578 O OE1  A GLU A 1 131 ? 10.832  -12.276 28.229  0.5   17.815 ? 299 GLU A OE1  1 ? 
ATOM   1579 O OE1  B GLU A 1 131 ? 10.675  -12.6   28.768  0.5   27.855 ? 299 GLU A OE1  1 ? 
ATOM   1580 O OE2  A GLU A 1 131 ? 12.567  -11.752 29.437  0.5   15.168 ? 299 GLU A OE2  1 ? 
ATOM   1581 O OE2  B GLU A 1 131 ? 8.695   -13.311 28.031  0.5   28.134 ? 299 GLU A OE2  1 ? 
ATOM   1582 H H    A GLU A 1 131 ? 11.146  -14.75  24.531  0.5   18.1   ? 299 GLU A H    1 c 
ATOM   1583 H H    B GLU A 1 131 ? 11.147  -14.747 24.531  0.5   19.428 ? 299 GLU A H    1 c 
ATOM   1584 H HA   A GLU A 1 131 ? 11.774  -12.542 25.916  0.5   18.125 ? 299 GLU A HA   1 c 
ATOM   1585 H HA   B GLU A 1 131 ? 11.778  -12.54  25.916  0.5   20.614 ? 299 GLU A HA   1 c 
ATOM   1586 H HB2  A GLU A 1 131 ? 11.216  -14.59  26.995  0.5   17.96  ? 299 GLU A HB2  1 c 
ATOM   1587 H HB2  B GLU A 1 131 ? 12.351  -15.255 26.524  0.5   22.575 ? 299 GLU A HB2  1 c 
ATOM   1588 H HB3  A GLU A 1 131 ? 12.645  -15.16  26.613  0.5   17.96  ? 299 GLU A HB3  1 c 
ATOM   1589 H HB3  B GLU A 1 131 ? 12.571  -14.078 27.561  0.5   22.575 ? 299 GLU A HB3  1 c 
ATOM   1590 H HG2  A GLU A 1 131 ? 12.786  -14.379 28.793  0.5   17.339 ? 299 GLU A HG2  1 c 
ATOM   1591 H HG2  B GLU A 1 131 ? 10.016  -14.577 26.44   0.5   24.363 ? 299 GLU A HG2  1 c 
ATOM   1592 H HG3  A GLU A 1 131 ? 13.662  -13.426 27.892  0.5   17.339 ? 299 GLU A HG3  1 c 
ATOM   1593 H HG3  B GLU A 1 131 ? 10.465  -15.33  27.738  0.5   24.357 ? 299 GLU A HG3  1 c 
ATOM   1594 N N    . ARG A 1 132 ? 14.214  -13.753 24.253  1     17.702 ? 300 ARG A N    1 ? 
ATOM   1595 C CA   . ARG A 1 132 ? 15.576  -13.485 23.82   1     19.686 ? 300 ARG A CA   1 ? 
ATOM   1596 C C    . ARG A 1 132 ? 15.711  -12.153 23.087  1     18.696 ? 300 ARG A C    1 ? 
ATOM   1597 O O    . ARG A 1 132 ? 16.815  -11.625 22.995  1     19.502 ? 300 ARG A O    1 ? 
ATOM   1598 C CB   . ARG A 1 132 ? 16.104  -14.634 22.949  1     22.734 ? 300 ARG A CB   1 ? 
ATOM   1599 C CG   . ARG A 1 132 ? 16.35   -15.932 23.72   1     25.517 ? 300 ARG A CG   1 ? 
ATOM   1600 C CD   . ARG A 1 132 ? 16.605  -17.076 22.728  1     27.508 ? 300 ARG A CD   1 ? 
ATOM   1601 N NE   . ARG A 1 132 ? 15.377  -17.398 21.995  1     26.844 ? 300 ARG A NE   1 ? 
ATOM   1602 C CZ   . ARG A 1 132 ? 15.304  -18.254 20.989  1     32.669 ? 300 ARG A CZ   1 ? 
ATOM   1603 N NH1  . ARG A 1 132 ? 16.411  -18.822 20.574  1     32.981 ? 300 ARG A NH1  1 ? 
ATOM   1604 N NH2  . ARG A 1 132 ? 14.153  -18.499 20.399  1     34.95  ? 300 ARG A NH2  1 ? 
ATOM   1605 H H    A ARG A 1 132 ? 13.74   -14.419 23.843  0.5   18.482 ? 300 ARG A H    1 c 
ATOM   1606 H H    B ARG A 1 132 ? 13.739  -14.415 23.839  0.5   18.813 ? 300 ARG A H    1 c 
ATOM   1607 H HA   . ARG A 1 132 ? 16.154  -13.45  24.625  1     19.624 ? 300 ARG A HA   1 c 
ATOM   1608 H HB2  . ARG A 1 132 ? 15.463  -14.804 22.228  1     22.609 ? 300 ARG A HB2  1 c 
ATOM   1609 H HB3  . ARG A 1 132 ? 16.948  -14.352 22.534  1     22.571 ? 300 ARG A HB3  1 c 
ATOM   1610 H HG2  . ARG A 1 132 ? 17.131  -15.827 24.306  1     25.279 ? 300 ARG A HG2  1 c 
ATOM   1611 H HG3  . ARG A 1 132 ? 15.565  -16.145 24.271  1     25.258 ? 300 ARG A HG3  1 c 
ATOM   1612 H HD2  . ARG A 1 132 ? 17.302  -16.809 22.095  1     26.924 ? 300 ARG A HD2  1 c 
ATOM   1613 H HD3  . ARG A 1 132 ? 16.914  -17.87  23.21   1     26.902 ? 300 ARG A HD3  1 c 
ATOM   1614 H HE   . ARG A 1 132 ? 14.638  -17.006 22.241  1     28.222 ? 300 ARG A HE   1 c 
ATOM   1615 H HH11 . ARG A 1 132 ? 16.797  -19.446 21.068  1     32.853 ? 300 ARG A HH11 1 c 
ATOM   1616 H HH12 . ARG A 1 132 ? 16.767  -18.577 19.803  1     32.877 ? 300 ARG A HH12 1 c 
ATOM   1617 H HH21 . ARG A 1 132 ? 13.579  -17.84  20.264  1     34.179 ? 300 ARG A HH21 1 c 
ATOM   1618 H HH22 . ARG A 1 132 ? 13.959  -19.322 20.14   1     34.219 ? 300 ARG A HH22 1 c 
ATOM   1619 N N    . TRP A 1 133 ? 14.603  -11.551 22.617  1     17.532 ? 301 TRP A N    1 ? 
ATOM   1620 C CA   . TRP A 1 133 ? 14.67   -10.24  21.983  1     17.814 ? 301 TRP A CA   1 ? 
ATOM   1621 C C    . TRP A 1 133 ? 14.68   -9.124  23.038  1     16.379 ? 301 TRP A C    1 ? 
ATOM   1622 O O    . TRP A 1 133 ? 15.242  -8.044  22.814  1     18.191 ? 301 TRP A O    1 ? 
ATOM   1623 C CB   . TRP A 1 133 ? 13.465  -10.044 21.06   1     19.614 ? 301 TRP A CB   1 ? 
ATOM   1624 C CG   . TRP A 1 133 ? 13.4    -8.694  20.388  1     16.126 ? 301 TRP A CG   1 ? 
ATOM   1625 C CD1  . TRP A 1 133 ? 12.384  -7.779  20.468  1     14.93  ? 301 TRP A CD1  1 ? 
ATOM   1626 C CD2  . TRP A 1 133 ? 14.362  -8.124  19.474  1     14.46  ? 301 TRP A CD2  1 ? 
ATOM   1627 N NE1  . TRP A 1 133 ? 12.633  -6.709  19.638  1     15.624 ? 301 TRP A NE1  1 ? 
ATOM   1628 C CE2  . TRP A 1 133 ? 13.833  -6.907  19.018  1     14.533 ? 301 TRP A CE2  1 ? 
ATOM   1629 C CE3  . TRP A 1 133 ? 15.593  -8.574  18.957  1     15.461 ? 301 TRP A CE3  1 ? 
ATOM   1630 C CZ2  . TRP A 1 133 ? 14.514  -6.112  18.104  1     16.038 ? 301 TRP A CZ2  1 ? 
ATOM   1631 C CZ3  . TRP A 1 133 ? 16.256  -7.783  18.057  1     16.286 ? 301 TRP A CZ3  1 ? 
ATOM   1632 C CH2  . TRP A 1 133 ? 15.711  -6.586  17.634  1     15.656 ? 301 TRP A CH2  1 ? 
ATOM   1633 H H    . TRP A 1 133 ? 13.797  -11.978 22.658  1     17.899 ? 301 TRP A H    1 c 
ATOM   1634 H HA   . TRP A 1 133 ? 15.5    -10.182 21.438  1     17.801 ? 301 TRP A HA   1 c 
ATOM   1635 H HB2  . TRP A 1 133 ? 13.488  -10.74  20.368  1     18.343 ? 301 TRP A HB2  1 c 
ATOM   1636 H HB3  . TRP A 1 133 ? 12.647  -10.175 21.585  1     18.338 ? 301 TRP A HB3  1 c 
ATOM   1637 H HD1  . TRP A 1 133 ? 11.601  -7.882  20.982  1     15.383 ? 301 TRP A HD1  1 c 
ATOM   1638 H HE1  . TRP A 1 133 ? 12.121  -6.008  19.548  1     15.224 ? 301 TRP A HE1  1 c 
ATOM   1639 H HE3  . TRP A 1 133 ? 15.961  -9.393  19.243  1     15.514 ? 301 TRP A HE3  1 c 
ATOM   1640 H HZ2  . TRP A 1 133 ? 14.158  -5.292  17.807  1     15.594 ? 301 TRP A HZ2  1 c 
ATOM   1641 H HZ3  . TRP A 1 133 ? 17.087  -8.064  17.712  1     15.927 ? 301 TRP A HZ3  1 c 
ATOM   1642 H HH2  . TRP A 1 133 ? 16.193  -6.062  17.019  1     15.876 ? 301 TRP A HH2  1 c 
ATOM   1643 N N    . TRP A 1 134 ? 14.113  -9.404  24.201  1     18.733 ? 302 TRP A N    1 ? 
ATOM   1644 C CA   . TRP A 1 134 ? 13.929  -8.376  25.212  1     18.537 ? 302 TRP A CA   1 ? 
ATOM   1645 C C    . TRP A 1 134 ? 15.251  -7.74   25.625  1     17.724 ? 302 TRP A C    1 ? 
ATOM   1646 O O    . TRP A 1 134 ? 15.316  -6.528  25.752  1     20.741 ? 302 TRP A O    1 ? 
ATOM   1647 C CB   . TRP A 1 134 ? 13.174  -8.905  26.443  1     20.462 ? 302 TRP A CB   1 ? 
ATOM   1648 C CG   . TRP A 1 134 ? 13.183  -7.878  27.544  1     19.303 ? 302 TRP A CG   1 ? 
ATOM   1649 C CD1  . TRP A 1 134 ? 13.838  -7.97   28.73   1     21.482 ? 302 TRP A CD1  1 ? 
ATOM   1650 C CD2  . TRP A 1 134 ? 12.556  -6.582  27.516  1     19.12  ? 302 TRP A CD2  1 ? 
ATOM   1651 N NE1  . TRP A 1 134 ? 13.622  -6.824  29.47   1     21.731 ? 302 TRP A NE1  1 ? 
ATOM   1652 C CE2  . TRP A 1 134 ? 12.864  -5.948  28.743  1     21.723 ? 302 TRP A CE2  1 ? 
ATOM   1653 C CE3  . TRP A 1 134 ? 11.767  -5.881  26.586  1     16.972 ? 302 TRP A CE3  1 ? 
ATOM   1654 C CZ2  . TRP A 1 134 ? 12.42   -4.658  29.06   1     20.491 ? 302 TRP A CZ2  1 ? 
ATOM   1655 C CZ3  . TRP A 1 134 ? 11.345  -4.607  26.894  1     17.832 ? 302 TRP A CZ3  1 ? 
ATOM   1656 C CH2  . TRP A 1 134 ? 11.67   -4.001  28.103  1     16.9   ? 302 TRP A CH2  1 ? 
ATOM   1657 H H    . TRP A 1 134 ? 13.821  -10.251 24.378  1     18.112 ? 302 TRP A H    1 c 
ATOM   1658 H HA   . TRP A 1 134 ? 13.367  -7.662  24.806  1     18.757 ? 302 TRP A HA   1 c 
ATOM   1659 H HB2  . TRP A 1 134 ? 12.247  -9.099  26.187  1     19.746 ? 302 TRP A HB2  1 c 
ATOM   1660 H HB3  . TRP A 1 134 ? 13.605  -9.725  26.76   1     19.765 ? 302 TRP A HB3  1 c 
ATOM   1661 H HD1  . TRP A 1 134 ? 14.331  -8.716  29.031  1     21.002 ? 302 TRP A HD1  1 c 
ATOM   1662 H HE1  . TRP A 1 134 ? 13.952  -6.668  30.263  1     21.622 ? 302 TRP A HE1  1 c 
ATOM   1663 H HE3  . TRP A 1 134 ? 11.553  -6.269  25.755  1     17.681 ? 302 TRP A HE3  1 c 
ATOM   1664 H HZ2  . TRP A 1 134 ? 12.64   -4.251  29.88   1     19.819 ? 302 TRP A HZ2  1 c 
ATOM   1665 H HZ3  . TRP A 1 134 ? 10.82   -4.133  26.27   1     17.461 ? 302 TRP A HZ3  1 c 
ATOM   1666 H HH2  . TRP A 1 134 ? 11.347  -3.137  28.287  1     17.916 ? 302 TRP A HH2  1 c 
ATOM   1667 N N    . PRO A 1 135 ? 16.362  -8.467  25.867  1     20.711 ? 303 PRO A N    1 ? 
ATOM   1668 C CA   . PRO A 1 135 ? 17.62   -7.793  26.228  1     21.113 ? 303 PRO A CA   1 ? 
ATOM   1669 C C    . PRO A 1 135 ? 18.098  -6.761  25.212  1     20.45  ? 303 PRO A C    1 ? 
ATOM   1670 O O    . PRO A 1 135 ? 18.719  -5.774  25.584  1     18.795 ? 303 PRO A O    1 ? 
ATOM   1671 C CB   . PRO A 1 135 ? 18.618  -8.961  26.428  1     22.305 ? 303 PRO A CB   1 ? 
ATOM   1672 C CG   . PRO A 1 135 ? 17.731  -10.074 26.87   1     22.657 ? 303 PRO A CG   1 ? 
ATOM   1673 C CD   . PRO A 1 135 ? 16.471  -9.923  25.991  1     22.159 ? 303 PRO A CD   1 ? 
ATOM   1674 H HA   . PRO A 1 135 ? 17.481  -7.344  27.1    1     21.117 ? 303 PRO A HA   1 c 
ATOM   1675 H HB2  . PRO A 1 135 ? 19.077  -9.185  25.584  1     22.108 ? 303 PRO A HB2  1 c 
ATOM   1676 H HB3  . PRO A 1 135 ? 19.287  -8.743  27.118  1     22.116 ? 303 PRO A HB3  1 c 
ATOM   1677 H HG2  . PRO A 1 135 ? 18.159  -10.944 26.721  1     22.465 ? 303 PRO A HG2  1 c 
ATOM   1678 H HG3  . PRO A 1 135 ? 17.507  -9.988  27.82   1     22.465 ? 303 PRO A HG3  1 c 
ATOM   1679 H HD2  . PRO A 1 135 ? 16.59   -10.35  25.118  1     21.874 ? 303 PRO A HD2  1 c 
ATOM   1680 H HD3  . PRO A 1 135 ? 15.69   -10.296 26.44   1     21.849 ? 303 PRO A HD3  1 c 
ATOM   1681 N N    . ILE A 1 136 ? 17.826  -6.994  23.938  1     17.01  ? 304 ILE A N    1 ? 
ATOM   1682 C CA   . ILE A 1 136 ? 18.21   -6.034  22.904  1     16.872 ? 304 ILE A CA   1 ? 
ATOM   1683 C C    . ILE A 1 136 ? 17.407  -4.761  23.071  1     16.989 ? 304 ILE A C    1 ? 
ATOM   1684 O O    . ILE A 1 136 ? 17.974  -3.671  23.062  1     19.28  ? 304 ILE A O    1 ? 
ATOM   1685 C CB   . ILE A 1 136 ? 18.069  -6.636  21.512  1     17.839 ? 304 ILE A CB   1 ? 
ATOM   1686 C CG1  . ILE A 1 136 ? 19.13   -7.767  21.395  1     24.831 ? 304 ILE A CG1  1 ? 
ATOM   1687 C CG2  . ILE A 1 136 ? 18.189  -5.539  20.451  1     17.233 ? 304 ILE A CG2  1 ? 
ATOM   1688 C CD1  . ILE A 1 136 ? 18.92   -8.734  20.269  1     30.648 ? 304 ILE A CD1  1 ? 
ATOM   1689 H H    . ILE A 1 136 ? 17.401  -7.765  23.691  1     17.863 ? 304 ILE A H    1 c 
ATOM   1690 H HA   . ILE A 1 136 ? 19.154  -5.814  23.036  1     17.167 ? 304 ILE A HA   1 c 
ATOM   1691 H HB   . ILE A 1 136 ? 17.183  -7.039  21.44   1     18.637 ? 304 ILE A HB   1 c 
ATOM   1692 H HG12 . ILE A 1 136 ? 20.01   -7.353  21.287  1     24.161 ? 304 ILE A HG12 1 c 
ATOM   1693 H HG13 . ILE A 1 136 ? 19.146  -8.273  22.232  1     24.073 ? 304 ILE A HG13 1 c 
ATOM   1694 H HG21 . ILE A 1 136 ? 18.445  -5.937  19.602  1     17.469 ? 304 ILE A HG21 1 c 
ATOM   1695 H HG22 . ILE A 1 136 ? 18.866  -4.894  20.718  1     17.417 ? 304 ILE A HG22 1 c 
ATOM   1696 H HG23 . ILE A 1 136 ? 17.334  -5.088  20.347  1     17.42  ? 304 ILE A HG23 1 c 
ATOM   1697 H HD11 . ILE A 1 136 ? 18.056  -9.175  20.375  1     28.628 ? 304 ILE A HD11 1 c 
ATOM   1698 H HD12 . ILE A 1 136 ? 19.629  -9.404  20.278  1     28.724 ? 304 ILE A HD12 1 c 
ATOM   1699 H HD13 . ILE A 1 136 ? 18.937  -8.256  19.418  1     28.648 ? 304 ILE A HD13 1 c 
ATOM   1700 N N    . VAL A 1 137 ? 16.083  -4.921  23.235  1     16.069 ? 305 VAL A N    1 ? 
ATOM   1701 C CA   . VAL A 1 137 ? 15.209  -3.798  23.457  1     15.869 ? 305 VAL A CA   1 ? 
ATOM   1702 C C    . VAL A 1 137 ? 15.597  -3.089  24.745  1     13.922 ? 305 VAL A C    1 ? 
ATOM   1703 O O    . VAL A 1 137 ? 15.745  -1.88   24.745  1     15.118 ? 305 VAL A O    1 ? 
ATOM   1704 C CB   . VAL A 1 137 ? 13.719  -4.185  23.486  1     16.174 ? 305 VAL A CB   1 ? 
ATOM   1705 C CG1  . VAL A 1 137 ? 12.841  -3.003  23.84   1     17.587 ? 305 VAL A CG1  1 ? 
ATOM   1706 C CG2  . VAL A 1 137 ? 13.322  -4.799  22.17   1     16.603 ? 305 VAL A CG2  1 ? 
ATOM   1707 H H    . VAL A 1 137 ? 15.724  -5.762  23.211  1     16.249 ? 305 VAL A H    1 c 
ATOM   1708 H HA   . VAL A 1 137 ? 15.34   -3.171  22.719  1     15.604 ? 305 VAL A HA   1 c 
ATOM   1709 H HB   . VAL A 1 137 ? 13.609  -4.869  24.188  1     16.452 ? 305 VAL A HB   1 c 
ATOM   1710 H HG11 . VAL A 1 137 ? 13.199  -2.197  23.431  1     17.126 ? 305 VAL A HG11 1 c 
ATOM   1711 H HG12 . VAL A 1 137 ? 12.816  -2.892  24.805  1     17.131 ? 305 VAL A HG12 1 c 
ATOM   1712 H HG13 . VAL A 1 137 ? 11.939  -3.155  23.512  1     17.138 ? 305 VAL A HG13 1 c 
ATOM   1713 H HG21 . VAL A 1 137 ? 12.356  -4.905  22.138  1     16.483 ? 305 VAL A HG21 1 c 
ATOM   1714 H HG22 . VAL A 1 137 ? 13.743  -5.67   22.075  1     16.472 ? 305 VAL A HG22 1 c 
ATOM   1715 H HG23 . VAL A 1 137 ? 13.607  -4.222  21.443  1     16.47  ? 305 VAL A HG23 1 c 
ATOM   1716 N N    . GLN A 1 138 ? 15.763  -3.85   25.819  1     14.22  ? 306 GLN A N    1 ? 
ATOM   1717 C CA   . GLN A 1 138 ? 16.141  -3.295  27.112  1     14.96  ? 306 GLN A CA   1 ? 
ATOM   1718 C C    . GLN A 1 138 ? 17.433  -2.505  27.007  1     15.316 ? 306 GLN A C    1 ? 
ATOM   1719 O O    . GLN A 1 138 ? 17.585  -1.45   27.633  1     16.547 ? 306 GLN A O    1 ? 
ATOM   1720 C CB   . GLN A 1 138 ? 16.238  -4.437  28.124  1     17.532 ? 306 GLN A CB   1 ? 
ATOM   1721 C CG   . GLN A 1 138 ? 16.53   -3.914  29.522  1     23.089 ? 306 GLN A CG   1 ? 
ATOM   1722 C CD   . GLN A 1 138 ? 17.086  -4.981  30.435  1     29.652 ? 306 GLN A CD   1 ? 
ATOM   1723 O OE1  . GLN A 1 138 ? 17.013  -6.173  30.161  1     37.982 ? 306 GLN A OE1  1 ? 
ATOM   1724 N NE2  . GLN A 1 138 ? 17.789  -4.542  31.456  1     40.104 ? 306 GLN A NE2  1 ? 
ATOM   1725 H H    . GLN A 1 138 ? 15.627  -4.752  25.753  1     14.377 ? 306 GLN A H    1 c 
ATOM   1726 H HA   . GLN A 1 138 ? 15.421  -2.679  27.404  1     15.315 ? 306 GLN A HA   1 c 
ATOM   1727 H HB2  . GLN A 1 138 ? 15.398  -4.936  28.131  1     18.028 ? 306 GLN A HB2  1 c 
ATOM   1728 H HB3  . GLN A 1 138 ? 16.953  -5.047  27.846  1     18.139 ? 306 GLN A HB3  1 c 
ATOM   1729 H HG2  . GLN A 1 138 ? 17.172  -3.178  29.478  1     22.912 ? 306 GLN A HG2  1 c 
ATOM   1730 H HG3  . GLN A 1 138 ? 15.702  -3.566  29.913  1     22.931 ? 306 GLN A HG3  1 c 
ATOM   1731 H HE21 . GLN A 1 138 ? 18.393  -5.069  31.837  1     36.478 ? 306 GLN A HE21 1 c 
ATOM   1732 H HE22 . GLN A 1 138 ? 17.661  -3.721  31.766  1     36.256 ? 306 GLN A HE22 1 c 
ATOM   1733 N N    . GLY A 1 139 ? 18.401  -3.035  26.285  1     16.047 ? 307 GLY A N    1 ? 
ATOM   1734 C CA   . GLY A 1 139 ? 19.706  -2.386  26.121  1     16.601 ? 307 GLY A CA   1 ? 
ATOM   1735 C C    . GLY A 1 139 ? 19.585  -1.04   25.412  1     16.214 ? 307 GLY A C    1 ? 
ATOM   1736 O O    . GLY A 1 139 ? 20.296  -0.097  25.752  1     15.62  ? 307 GLY A O    1 ? 
ATOM   1737 H H    . GLY A 1 139 ? 18.265  -3.843  25.879  1     15.971 ? 307 GLY A H    1 c 
ATOM   1738 H HA2  . GLY A 1 139 ? 20.113  -2.254  27.009  1     16.382 ? 307 GLY A HA2  1 c 
ATOM   1739 H HA3  . GLY A 1 139 ? 20.297  -2.979  25.601  1     16.382 ? 307 GLY A HA3  1 c 
ATOM   1740 N N    . ARG A 1 140 ? 18.585  -0.893  24.519  1     16.439 ? 308 ARG A N    1 ? 
ATOM   1741 C CA   . ARG A 1 140 ? 18.351  0.354   23.814  1     14.578 ? 308 ARG A CA   1 ? 
ATOM   1742 C C    . ARG A 1 140 ? 17.69   1.363   24.749  1     14.526 ? 308 ARG A C    1 ? 
ATOM   1743 O O    . ARG A 1 140 ? 18.081  2.526   24.746  1     14.84  ? 308 ARG A O    1 ? 
ATOM   1744 C CB   . ARG A 1 140 ? 17.514  0.172   22.545  1     14.754 ? 308 ARG A CB   1 ? 
ATOM   1745 C CG   . ARG A 1 140 ? 18.336  -0.556  21.488  1     15.057 ? 308 ARG A CG   1 ? 
ATOM   1746 C CD   . ARG A 1 140 ? 17.59   -1.196  20.34   1     15.697 ? 308 ARG A CD   1 ? 
ATOM   1747 N NE   . ARG A 1 140 ? 18.569  -1.838  19.438  1     17.417 ? 308 ARG A NE   1 ? 
ATOM   1748 C CZ   . ARG A 1 140 ? 18.278  -2.127  18.166  1     19.062 ? 308 ARG A CZ   1 ? 
ATOM   1749 N NH1  . ARG A 1 140 ? 17.074  -1.888  17.685  1     20.022 ? 308 ARG A NH1  1 ? 
ATOM   1750 N NH2  . ARG A 1 140 ? 19.183  -2.663  17.351  1     20.516 ? 308 ARG A NH2  1 ? 
ATOM   1751 H H    . ARG A 1 140 ? 18.046  -1.605  24.33   1     15.927 ? 308 ARG A H    1 c 
ATOM   1752 H HA   . ARG A 1 140 ? 19.23   0.72    23.538  1     14.956 ? 308 ARG A HA   1 c 
ATOM   1753 H HB2  . ARG A 1 140 ? 16.709  -0.348  22.75   1     14.784 ? 308 ARG A HB2  1 c 
ATOM   1754 H HB3  . ARG A 1 140 ? 17.239  1.048   22.199  1     14.781 ? 308 ARG A HB3  1 c 
ATOM   1755 H HG2  . ARG A 1 140 ? 18.984  0.08    21.113  1     15.135 ? 308 ARG A HG2  1 c 
ATOM   1756 H HG3  . ARG A 1 140 ? 18.864  -1.254  21.932  1     15.149 ? 308 ARG A HG3  1 c 
ATOM   1757 H HD2  . ARG A 1 140 ? 16.963  -1.868  20.676  1     15.942 ? 308 ARG A HD2  1 c 
ATOM   1758 H HD3  . ARG A 1 140 ? 17.087  -0.514  19.852  1     15.975 ? 308 ARG A HD3  1 c 
ATOM   1759 H HE   . ARG A 1 140 ? 19.359  -2.03   19.742  1     17.379 ? 308 ARG A HE   1 c 
ATOM   1760 H HH11 . ARG A 1 140 ? 16.384  -2.36   17.973  1     19.697 ? 308 ARG A HH11 1 c 
ATOM   1761 H HH12 . ARG A 1 140 ? 16.961  -1.257  17.076  1     19.716 ? 308 ARG A HH12 1 c 
ATOM   1762 H HH21 . ARG A 1 140 ? 20.024  -2.396  17.389  1     20.052 ? 308 ARG A HH21 1 c 
ATOM   1763 H HH22 . ARG A 1 140 ? 18.934  -3.278  16.769  1     20.029 ? 308 ARG A HH22 1 c 
ATOM   1764 N N    . ILE A 1 141 ? 16.775  0.89    25.579  1     15.669 ? 309 ILE A N    1 ? 
ATOM   1765 C CA   . ILE A 1 141 ? 16.147  1.744   26.575  1     14.152 ? 309 ILE A CA   1 ? 
ATOM   1766 C C    . ILE A 1 141 ? 17.259  2.249   27.506  1     15.09  ? 309 ILE A C    1 ? 
ATOM   1767 O O    . ILE A 1 141 ? 17.328  3.428   27.843  1     16.361 ? 309 ILE A O    1 ? 
ATOM   1768 C CB   . ILE A 1 141 ? 15.039  1.008   27.359  1     14.706 ? 309 ILE A CB   1 ? 
ATOM   1769 C CG1  . ILE A 1 141 ? 13.933  0.482   26.453  1     16.088 ? 309 ILE A CG1  1 ? 
ATOM   1770 C CG2  . ILE A 1 141 ? 14.49   1.972   28.414  1     15.919 ? 309 ILE A CG2  1 ? 
ATOM   1771 C CD1  . ILE A 1 141 ? 13.048  -0.534  27.13   1     16.655 ? 309 ILE A CD1  1 ? 
ATOM   1772 H H    . ILE A 1 141 ? 16.535  0.01    25.536  1     15.057 ? 309 ILE A H    1 c 
ATOM   1773 H HA   . ILE A 1 141 ? 15.748  2.51    26.119  1     14.714 ? 309 ILE A HA   1 c 
ATOM   1774 H HB   . ILE A 1 141 ? 15.447  0.248   27.819  1     15.079 ? 309 ILE A HB   1 c 
ATOM   1775 H HG12 . ILE A 1 141 ? 13.38   1.235   26.161  1     15.887 ? 309 ILE A HG12 1 c 
ATOM   1776 H HG13 . ILE A 1 141 ? 14.329  0.075   25.658  1     15.879 ? 309 ILE A HG13 1 c 
ATOM   1777 H HG21 . ILE A 1 141 ? 13.582  1.72    28.649  1     15.564 ? 309 ILE A HG21 1 c 
ATOM   1778 H HG22 . ILE A 1 141 ? 14.489  2.879   28.064  1     15.539 ? 309 ILE A HG22 1 c 
ATOM   1779 H HG23 . ILE A 1 141 ? 15.046  1.935   29.211  1     15.55  ? 309 ILE A HG23 1 c 
ATOM   1780 H HD11 . ILE A 1 141 ? 13.586  -1.119  27.696  1     16.461 ? 309 ILE A HD11 1 c 
ATOM   1781 H HD12 . ILE A 1 141 ? 12.595  -1.07   26.452  1     16.474 ? 309 ILE A HD12 1 c 
ATOM   1782 H HD13 . ILE A 1 141 ? 12.383  -0.076  27.678  1     16.472 ? 309 ILE A HD13 1 c 
ATOM   1783 N N    . ASP A 1 142 ? 18.103  1.33    27.999  1     15.294 ? 310 ASP A N    1 ? 
ATOM   1784 C CA   . ASP A 1 142 ? 19.181  1.685   28.899  1     15.317 ? 310 ASP A CA   1 ? 
ATOM   1785 C C    . ASP A 1 142 ? 20.146  2.698   28.295  1     15.17  ? 310 ASP A C    1 ? 
ATOM   1786 O O    . ASP A 1 142 ? 20.548  3.625   28.976  1     15.202 ? 310 ASP A O    1 ? 
ATOM   1787 C CB   . ASP A 1 142 ? 19.932  0.463   29.374  1     14.016 ? 310 ASP A CB   1 ? 
ATOM   1788 C CG   . ASP A 1 142 ? 19.167  -0.442  30.33   1     17.589 ? 310 ASP A CG   1 ? 
ATOM   1789 O OD1  . ASP A 1 142 ? 18.152  -0      30.907  1     19.171 ? 310 ASP A OD1  1 ? 
ATOM   1790 O OD2  . ASP A 1 142 ? 19.553  -1.618  30.442  1     19.021 ? 310 ASP A OD2  1 ? 
ATOM   1791 H H    . ASP A 1 142 ? 17.992  0.451   27.774  1     15.237 ? 310 ASP A H    1 c 
ATOM   1792 H HA   . ASP A 1 142 ? 18.779  2.099   29.696  1     15.071 ? 310 ASP A HA   1 c 
ATOM   1793 H HB2  . ASP A 1 142 ? 20.189  -0.069  28.593  1     15.07  ? 310 ASP A HB2  1 c 
ATOM   1794 H HB3  . ASP A 1 142 ? 20.753  0.749   29.826  1     15.071 ? 310 ASP A HB3  1 c 
ATOM   1795 N N    . ARG A 1 143 ? 20.518  2.522   27.022  1     16.68  ? 311 ARG A N    1 ? 
ATOM   1796 C CA   . ARG A 1 143 ? 21.313  3.524   26.315  1     17.958 ? 311 ARG A CA   1 ? 
ATOM   1797 C C    . ARG A 1 143 ? 20.587  4.863   26.216  1     16.858 ? 311 ARG A C    1 ? 
ATOM   1798 O O    . ARG A 1 143 ? 21.233  5.892   26.401  1     15.496 ? 311 ARG A O    1 ? 
ATOM   1799 C CB   . ARG A 1 143 ? 21.697  3.015   24.911  1     17.636 ? 311 ARG A CB   1 ? 
ATOM   1800 C CG   . ARG A 1 143 ? 22.762  1.933   24.98   1     17.753 ? 311 ARG A CG   1 ? 
ATOM   1801 C CD   . ARG A 1 143 ? 24.147  2.545   25.243  1     17.988 ? 311 ARG A CD   1 ? 
ATOM   1802 N NE   . ARG A 1 143 ? 25.166  1.496   25.25   1     17.321 ? 311 ARG A NE   1 ? 
ATOM   1803 C CZ   . ARG A 1 143 ? 26.488  1.707   25.142  1     19.41  ? 311 ARG A CZ   1 ? 
ATOM   1804 N NH1  . ARG A 1 143 ? 26.984  2.914   25.178  1     19.084 ? 311 ARG A NH1  1 ? 
ATOM   1805 N NH2  . ARG A 1 143 ? 27.309  0.695   25.049  1     20.149 ? 311 ARG A NH2  1 ? 
ATOM   1806 H H    . ARG A 1 143 ? 20.28   1.757   26.584  1     16.577 ? 311 ARG A H    1 c 
ATOM   1807 H HA   . ARG A 1 143 ? 22.143  3.668   26.833  1     17.419 ? 311 ARG A HA   1 c 
ATOM   1808 H HB2  . ARG A 1 143 ? 20.9    2.653   24.469  1     17.721 ? 311 ARG A HB2  1 c 
ATOM   1809 H HB3  . ARG A 1 143 ? 22.031  3.762   24.371  1     17.705 ? 311 ARG A HB3  1 c 
ATOM   1810 H HG2  . ARG A 1 143 ? 22.546  1.303   25.701  1     17.773 ? 311 ARG A HG2  1 c 
ATOM   1811 H HG3  . ARG A 1 143 ? 22.784  1.442   24.131  1     17.834 ? 311 ARG A HG3  1 c 
ATOM   1812 H HD2  . ARG A 1 143 ? 24.357  3.199   24.548  1     17.783 ? 311 ARG A HD2  1 c 
ATOM   1813 H HD3  . ARG A 1 143 ? 24.152  3.004   26.106  1     17.775 ? 311 ARG A HD3  1 c 
ATOM   1814 H HE   . ARG A 1 143 ? 24.899  0.67    25.333  1     17.964 ? 311 ARG A HE   1 c 
ATOM   1815 H HH11 . ARG A 1 143 ? 26.503  3.591   25.476  1     19.151 ? 311 ARG A HH11 1 c 
ATOM   1816 H HH12 . ARG A 1 143 ? 27.811  3.053   24.897  1     19.183 ? 311 ARG A HH12 1 c 
ATOM   1817 H HH21 . ARG A 1 143 ? 27.104  0.009   24.531  1     19.917 ? 311 ARG A HH21 1 c 
ATOM   1818 H HH22 . ARG A 1 143 ? 28.067  0.701   25.505  1     19.912 ? 311 ARG A HH22 1 c 
ATOM   1819 N N    . ALA A 1 144 ? 19.263  4.86    25.963  1     15.928 ? 312 ALA A N    1 ? 
ATOM   1820 C CA   . ALA A 1 144 ? 18.522  6.095   25.898  1     16.232 ? 312 ALA A CA   1 ? 
ATOM   1821 C C    . ALA A 1 144 ? 18.593  6.795   27.25   1     13.728 ? 312 ALA A C    1 ? 
ATOM   1822 O O    . ALA A 1 144 ? 18.762  7.992   27.327  1     14.577 ? 312 ALA A O    1 ? 
ATOM   1823 C CB   . ALA A 1 144 ? 17.063  5.873   25.466  1     17.07  ? 312 ALA A CB   1 ? 
ATOM   1824 H H    . ALA A 1 144 ? 18.826  4.07    25.819  1     16.227 ? 312 ALA A H    1 c 
ATOM   1825 H HA   . ALA A 1 144 ? 18.966  6.682   25.226  1     15.83  ? 312 ALA A HA   1 c 
ATOM   1826 H HB1  . ALA A 1 144 ? 17.038  5.301   24.681  1     16.82  ? 312 ALA A HB1  1 c 
ATOM   1827 H HB2  . ALA A 1 144 ? 16.569  5.45    26.188  1     16.821 ? 312 ALA A HB2  1 c 
ATOM   1828 H HB3  . ALA A 1 144 ? 16.652  6.728   25.253  1     16.821 ? 312 ALA A HB3  1 c 
ATOM   1829 N N    . LEU A 1 145 ? 18.467  6.028   28.348  1     13.274 ? 313 LEU A N    1 ? 
ATOM   1830 C CA   . LEU A 1 145 ? 18.481  6.624   29.677  1     13.397 ? 313 LEU A CA   1 ? 
ATOM   1831 C C    . LEU A 1 145 ? 19.9    7.109   29.975  1     14.617 ? 313 LEU A C    1 ? 
ATOM   1832 O O    . LEU A 1 145 ? 20.102  8.173   30.543  1     14.544 ? 313 LEU A O    1 ? 
ATOM   1833 C CB   . LEU A 1 145 ? 18.034  5.516   30.62   1     14.116 ? 313 LEU A CB   1 ? 
ATOM   1834 C CG   . LEU A 1 145 ? 16.548  5.138   30.599  1     13.659 ? 313 LEU A CG   1 ? 
ATOM   1835 C CD1  . LEU A 1 145 ? 16.398  3.801   31.29   1     15.458 ? 313 LEU A CD1  1 ? 
ATOM   1836 C CD2  . LEU A 1 145 ? 15.721  6.175   31.31   1     13.364 ? 313 LEU A CD2  1 ? 
ATOM   1837 H H    . LEU A 1 145 ? 18.356  5.125   28.264  1     13.451 ? 313 LEU A H    1 c 
ATOM   1838 H HA   . LEU A 1 145 ? 17.843  7.381   29.71   1     13.719 ? 313 LEU A HA   1 c 
ATOM   1839 H HB2  . LEU A 1 145 ? 18.565  4.71    30.424  1     13.86  ? 313 LEU A HB2  1 c 
ATOM   1840 H HB3  . LEU A 1 145 ? 18.268  5.787   31.538  1     13.85  ? 313 LEU A HB3  1 c 
ATOM   1841 H HG   . LEU A 1 145 ? 16.245  5.061   29.658  1     14.014 ? 313 LEU A HG   1 c 
ATOM   1842 H HD11 . LEU A 1 145 ? 16.842  3.112   30.767  1     14.89  ? 313 LEU A HD11 1 c 
ATOM   1843 H HD12 . LEU A 1 145 ? 15.455  3.583   31.376  1     14.887 ? 313 LEU A HD12 1 c 
ATOM   1844 H HD13 . LEU A 1 145 ? 16.801  3.845   32.174  1     14.892 ? 313 LEU A HD13 1 c 
ATOM   1845 H HD21 . LEU A 1 145 ? 15.737  7.004   30.806  1     13.47  ? 313 LEU A HD21 1 c 
ATOM   1846 H HD22 . LEU A 1 145 ? 16.084  6.329   32.198  1     13.46  ? 313 LEU A HD22 1 c 
ATOM   1847 H HD23 . LEU A 1 145 ? 14.803  5.863   31.387  1     13.465 ? 313 LEU A HD23 1 c 
ATOM   1848 N N    . ALA A 1 146 ? 20.88   6.304   29.625  1     14.211 ? 314 ALA A N    1 ? 
ATOM   1849 C CA   . ALA A 1 146 ? 22.283  6.653   29.905  1     17.464 ? 314 ALA A CA   1 ? 
ATOM   1850 C C    . ALA A 1 146 ? 22.737  7.943   29.228  1     15.799 ? 314 ALA A C    1 ? 
ATOM   1851 O O    . ALA A 1 146 ? 23.656  8.603   29.708  1     17.395 ? 314 ALA A O    1 ? 
ATOM   1852 C CB   . ALA A 1 146 ? 23.16   5.516   29.5    1     17.891 ? 314 ALA A CB   1 ? 
ATOM   1853 H H    . ALA A 1 146 ? 20.695  5.507   29.216  1     14.973 ? 314 ALA A H    1 c 
ATOM   1854 H HA   . ALA A 1 146 ? 22.371  6.783   30.888  1     16.537 ? 314 ALA A HA   1 c 
ATOM   1855 H HB1  . ALA A 1 146 ? 22.89   4.71    29.972  1     17.759 ? 314 ALA A HB1  1 c 
ATOM   1856 H HB2  . ALA A 1 146 ? 23.083  5.368   28.543  1     17.759 ? 314 ALA A HB2  1 c 
ATOM   1857 H HB3  . ALA A 1 146 ? 24.085  5.722   29.719  1     17.75  ? 314 ALA A HB3  1 c 
ATOM   1858 N N    . ALA A 1 147 ? 22.137  8.29    28.105  1     16.683 ? 315 ALA A N    1 ? 
ATOM   1859 C CA   . ALA A 1 147 ? 22.48   9.503   27.37   1     16.525 ? 315 ALA A CA   1 ? 
ATOM   1860 C C    . ALA A 1 147 ? 21.509  10.638  27.726  1     17.302 ? 315 ALA A C    1 ? 
ATOM   1861 O O    . ALA A 1 147 ? 21.678  11.75   27.225  1     17.567 ? 315 ALA A O    1 ? 
ATOM   1862 C CB   . ALA A 1 147 ? 22.474  9.225   25.894  1     16.871 ? 315 ALA A CB   1 ? 
ATOM   1863 H H    . ALA A 1 147 ? 21.498  7.74    27.752  1     16.407 ? 315 ALA A H    1 c 
ATOM   1864 H HA   . ALA A 1 147 ? 23.397  9.787   27.635  1     16.757 ? 315 ALA A HA   1 c 
ATOM   1865 H HB1  . ALA A 1 147 ? 23.138  8.547   25.686  1     16.767 ? 315 ALA A HB1  1 c 
ATOM   1866 H HB2  . ALA A 1 147 ? 21.596  8.908   25.624  1     16.766 ? 315 ALA A HB2  1 c 
ATOM   1867 H HB3  . ALA A 1 147 ? 22.684  10.04   25.406  1     16.771 ? 315 ALA A HB3  1 c 
ATOM   1868 N N    . GLY A 1 148 ? 20.514  10.368  28.606  1     14.499 ? 316 GLY A N    1 ? 
ATOM   1869 C CA   . GLY A 1 148 ? 19.663  11.414  29.124  1     16.13  ? 316 GLY A CA   1 ? 
ATOM   1870 C C    . GLY A 1 148 ? 18.611  11.889  28.127  1     17.022 ? 316 GLY A C    1 ? 
ATOM   1871 O O    . GLY A 1 148 ? 18.125  13.025  28.24   1     16.288 ? 316 GLY A O    1 ? 
ATOM   1872 H H    . GLY A 1 148 ? 20.357  9.509   28.868  1     15.512 ? 316 GLY A H    1 c 
ATOM   1873 H HA2  . GLY A 1 148 ? 19.212  11.08   29.931  1     15.928 ? 316 GLY A HA2  1 c 
ATOM   1874 H HA3  . GLY A 1 148 ? 20.224  12.178  29.393  1     15.958 ? 316 GLY A HA3  1 c 
ATOM   1875 N N    . PHE A 1 149 ? 18.211  10.998  27.178  1     15.546 ? 317 PHE A N    1 ? 
ATOM   1876 C CA   . PHE A 1 149 ? 17.096  11.307  26.32   1     16.828 ? 317 PHE A CA   1 ? 
ATOM   1877 C C    . PHE A 1 149 ? 15.855  11.534  27.174  1     17.507 ? 317 PHE A C    1 ? 
ATOM   1878 O O    . PHE A 1 149 ? 15.714  10.988  28.259  1     17.606 ? 317 PHE A O    1 ? 
ATOM   1879 C CB   . PHE A 1 149 ? 16.877  10.157  25.337  1     18.715 ? 317 PHE A CB   1 ? 
ATOM   1880 C CG   . PHE A 1 149 ? 17.849  10.127  24.166  1     16.686 ? 317 PHE A CG   1 ? 
ATOM   1881 C CD1  . PHE A 1 149 ? 19.073  9.473   24.255  1     16.687 ? 317 PHE A CD1  1 ? 
ATOM   1882 C CD2  . PHE A 1 149 ? 17.539  10.785  22.976  1     14.707 ? 317 PHE A CD2  1 ? 
ATOM   1883 C CE1  . PHE A 1 149 ? 19.962  9.445   23.17   1     15.691 ? 317 PHE A CE1  1 ? 
ATOM   1884 C CE2  . PHE A 1 149 ? 18.403  10.726  21.88   1     17.528 ? 317 PHE A CE2  1 ? 
ATOM   1885 C CZ   . PHE A 1 149 ? 19.615  10.066  21.965  1     17.105 ? 317 PHE A CZ   1 ? 
ATOM   1886 H H    . PHE A 1 149 ? 18.645  10.2    27.079  1     16.189 ? 317 PHE A H    1 c 
ATOM   1887 H HA   . PHE A 1 149 ? 17.301  12.136  25.812  1     17.012 ? 317 PHE A HA   1 c 
ATOM   1888 H HB2  . PHE A 1 149 ? 16.945  9.308   25.827  1     17.762 ? 317 PHE A HB2  1 c 
ATOM   1889 H HB3  . PHE A 1 149 ? 15.963  10.221  24.982  1     17.767 ? 317 PHE A HB3  1 c 
ATOM   1890 H HD1  . PHE A 1 149 ? 19.306  9.035   25.056  1     16.446 ? 317 PHE A HD1  1 c 
ATOM   1891 H HD2  . PHE A 1 149 ? 16.704  11.217  22.889  1     15.818 ? 317 PHE A HD2  1 c 
ATOM   1892 H HE1  . PHE A 1 149 ? 20.78   8.985   23.245  1     16.226 ? 317 PHE A HE1  1 c 
ATOM   1893 H HE2  . PHE A 1 149 ? 18.169  11.17   21.082  1     16.728 ? 317 PHE A HE2  1 c 
ATOM   1894 H HZ   . PHE A 1 149 ? 20.212  10.062  21.234  1     16.848 ? 317 PHE A HZ   1 c 
ATOM   1895 N N    . ASN A 1 150 ? 14.9    12.279  26.632  1     17.351 ? 318 ASN A N    1 ? 
ATOM   1896 C CA   . ASN A 1 150 ? 13.61   12.515  27.27   1     16.922 ? 318 ASN A CA   1 ? 
ATOM   1897 C C    . ASN A 1 150 ? 12.629  11.378  27.046  1     16.505 ? 318 ASN A C    1 ? 
ATOM   1898 O O    . ASN A 1 150 ? 11.548  11.326  27.635  1     18.427 ? 318 ASN A O    1 ? 
ATOM   1899 C CB   . ASN A 1 150 ? 13.014  13.805  26.749  1     18.044 ? 318 ASN A CB   1 ? 
ATOM   1900 C CG   . ASN A 1 150 ? 13.783  15.013  27.225  1     20.097 ? 318 ASN A CG   1 ? 
ATOM   1901 O OD1  . ASN A 1 150 ? 14.489  15.664  26.445  1     18.836 ? 318 ASN A OD1  1 ? 
ATOM   1902 N ND2  . ASN A 1 150 ? 13.631  15.35   28.501  1     21.664 ? 318 ASN A ND2  1 ? 
ATOM   1903 H H    . ASN A 1 150 ? 15.055  12.661  25.816  1     17.297 ? 318 ASN A H    1 c 
ATOM   1904 H HA   . ASN A 1 150 ? 13.753  12.622  28.237  1     17.178 ? 318 ASN A HA   1 c 
ATOM   1905 H HB2  . ASN A 1 150 ? 13.008  13.789  25.772  1     18.2   ? 318 ASN A HB2  1 c 
ATOM   1906 H HB3  . ASN A 1 150 ? 12.088  13.877  27.055  1     18.228 ? 318 ASN A HB3  1 c 
ATOM   1907 H HD21 . ASN A 1 150 ? 14.111  16.014  28.842  1     21.145 ? 318 ASN A HD21 1 c 
ATOM   1908 H HD22 . ASN A 1 150 ? 13.052  14.914  29.012  1     21.14  ? 318 ASN A HD22 1 c 
ATOM   1909 N N    . GLY A 1 151 ? 12.96   10.516  26.093  1     14.969 ? 319 GLY A N    1 ? 
ATOM   1910 C CA   . GLY A 1 151 ? 12.04   9.461   25.718  1     13.331 ? 319 GLY A CA   1 ? 
ATOM   1911 C C    . GLY A 1 151 ? 12.591  8.65    24.543  1     12.909 ? 319 GLY A C    1 ? 
ATOM   1912 O O    . GLY A 1 151 ? 13.689  8.884   24.069  1     14.621 ? 319 GLY A O    1 ? 
ATOM   1913 H H    . GLY A 1 151 ? 13.756  10.587  25.65   1     14.975 ? 319 GLY A H    1 c 
ATOM   1914 H HA2  . GLY A 1 151 ? 11.893  8.868   26.492  1     13.62  ? 319 GLY A HA2  1 c 
ATOM   1915 H HA3  . GLY A 1 151 ? 11.173  9.859   25.467  1     13.668 ? 319 GLY A HA3  1 c 
ATOM   1916 N N    . CYS A 1 152 ? 11.746  7.75    24.07   1     13.007 ? 320 CYS A N    1 ? 
ATOM   1917 C CA   . CYS A 1 152 ? 12.028  6.844   22.957  1     14.31  ? 320 CYS A CA   1 ? 
ATOM   1918 C C    . CYS A 1 152 ? 10.999  7.013   21.841  1     16.463 ? 320 CYS A C    1 ? 
ATOM   1919 O O    . CYS A 1 152 ? 9.846   7.369   22.087  1     18.141 ? 320 CYS A O    1 ? 
ATOM   1920 C CB   . CYS A 1 152 ? 12.131  5.396   23.392  1     15.055 ? 320 CYS A CB   1 ? 
ATOM   1921 S SG   . CYS A 1 152 ? 10.618  4.672   24.064  1     18.728 ? 320 CYS A SG   1 ? 
ATOM   1922 H H    . CYS A 1 152 ? 10.924  7.688   24.466  1     13.268 ? 320 CYS A H    1 c 
ATOM   1923 H HA   . CYS A 1 152 ? 12.912  7.09    22.594  1     14.563 ? 320 CYS A HA   1 c 
ATOM   1924 H HB2  . CYS A 1 152 ? 12.411  4.856   22.621  1     15.505 ? 320 CYS A HB2  1 c 
ATOM   1925 H HB3  . CYS A 1 152 ? 12.833  5.323   24.076  1     15.505 ? 320 CYS A HB3  1 c 
ATOM   1926 N N    . TYR A 1 153 ? 11.464  6.751   20.623  1     15.508 ? 321 TYR A N    1 ? 
ATOM   1927 C CA   . TYR A 1 153 ? 10.627  6.85    19.436  1     15.285 ? 321 TYR A CA   1 ? 
ATOM   1928 C C    . TYR A 1 153 ? 10.788  5.522   18.707  1     15.593 ? 321 TYR A C    1 ? 
ATOM   1929 O O    . TYR A 1 153 ? 11.85   5.224   18.189  1     16     ? 321 TYR A O    1 ? 
ATOM   1930 C CB   . TYR A 1 153 ? 11.036  8.105   18.656  1     15.034 ? 321 TYR A CB   1 ? 
ATOM   1931 C CG   . TYR A 1 153 ? 10.176  8.416   17.446  1     15.178 ? 321 TYR A CG   1 ? 
ATOM   1932 C CD1  . TYR A 1 153 ? 9       9.135   17.574  1     16.034 ? 321 TYR A CD1  1 ? 
ATOM   1933 C CD2  . TYR A 1 153 ? 10.448  7.839   16.217  1     18.023 ? 321 TYR A CD2  1 ? 
ATOM   1934 C CE1  . TYR A 1 153 ? 8.217   9.408   16.456  1     18.172 ? 321 TYR A CE1  1 ? 
ATOM   1935 C CE2  . TYR A 1 153 ? 9.678   8.116   15.096  1     16.094 ? 321 TYR A CE2  1 ? 
ATOM   1936 C CZ   . TYR A 1 153 ? 8.55    8.88    15.22   1     16.109 ? 321 TYR A CZ   1 ? 
ATOM   1937 O OH   . TYR A 1 153 ? 7.78    9.153   14.087  1     16.835 ? 321 TYR A OH   1 ? 
ATOM   1938 H H    . TYR A 1 153 ? 12.335  6.491   20.522  1     15.659 ? 321 TYR A H    1 c 
ATOM   1939 H HA   . TYR A 1 153 ? 9.686   6.951   19.715  1     15.359 ? 321 TYR A HA   1 c 
ATOM   1940 H HB2  . TYR A 1 153 ? 11.007  8.873   19.269  1     15.124 ? 321 TYR A HB2  1 c 
ATOM   1941 H HB3  . TYR A 1 153 ? 11.967  7.996   18.361  1     15.124 ? 321 TYR A HB3  1 c 
ATOM   1942 H HD1  . TYR A 1 153 ? 8.777   9.524   18.405  1     16.303 ? 321 TYR A HD1  1 c 
ATOM   1943 H HD2  . TYR A 1 153 ? 11.237  7.332   16.115  1     16.844 ? 321 TYR A HD2  1 c 
ATOM   1944 H HE1  . TYR A 1 153 ? 7.449   9.946   16.542  1     17.132 ? 321 TYR A HE1  1 c 
ATOM   1945 H HE2  . TYR A 1 153 ? 9.914   7.755   14.262  1     16.543 ? 321 TYR A HE2  1 c 
ATOM   1946 N N    . LEU A 1 154 ? 9.751   4.682   18.75   1     15.651 ? 322 LEU A N    1 ? 
ATOM   1947 C CA   . LEU A 1 154 ? 9.907   3.262   18.518  1     16.672 ? 322 LEU A CA   1 ? 
ATOM   1948 C C    . LEU A 1 154 ? 9.488   2.928   17.095  1     17.907 ? 322 LEU A C    1 ? 
ATOM   1949 O O    . LEU A 1 154 ? 8.294   3.012   16.806  1     17.904 ? 322 LEU A O    1 ? 
ATOM   1950 C CB   . LEU A 1 154 ? 9.038   2.497   19.521  1     15.495 ? 322 LEU A CB   1 ? 
ATOM   1951 C CG   . LEU A 1 154 ? 9.379   2.786   20.983  1     16.993 ? 322 LEU A CG   1 ? 
ATOM   1952 C CD1  . LEU A 1 154 ? 8.378   2.056   21.902  1     19.159 ? 322 LEU A CD1  1 ? 
ATOM   1953 C CD2  . LEU A 1 154 ? 10.794  2.409   21.327  1     17.566 ? 322 LEU A CD2  1 ? 
ATOM   1954 H H    . LEU A 1 154 ? 8.914   5.008   18.922  1     15.853 ? 322 LEU A H    1 c 
ATOM   1955 H HA   . LEU A 1 154 ? 10.853  3.014   18.653  1     16.47  ? 322 LEU A HA   1 c 
ATOM   1956 H HB2  . LEU A 1 154 ? 8.097   2.732   19.367  1     16.084 ? 322 LEU A HB2  1 c 
ATOM   1957 H HB3  . LEU A 1 154 ? 9.15    1.532   19.357  1     16.096 ? 322 LEU A HB3  1 c 
ATOM   1958 H HG   . LEU A 1 154 ? 9.276   3.76    21.139  1     17.177 ? 322 LEU A HG   1 c 
ATOM   1959 H HD11 . LEU A 1 154 ? 7.471   2.291   21.645  1     18.499 ? 322 LEU A HD11 1 c 
ATOM   1960 H HD12 . LEU A 1 154 ? 8.532   2.32    22.824  1     18.493 ? 322 LEU A HD12 1 c 
ATOM   1961 H HD13 . LEU A 1 154 ? 8.5     1.095   21.816  1     18.499 ? 322 LEU A HD13 1 c 
ATOM   1962 H HD21 . LEU A 1 154 ? 11.382  3.164   21.153  1     17.395 ? 322 LEU A HD21 1 c 
ATOM   1963 H HD22 . LEU A 1 154 ? 11.071  1.652   20.784  1     17.385 ? 322 LEU A HD22 1 c 
ATOM   1964 H HD23 . LEU A 1 154 ? 10.849  2.168   22.267  1     17.413 ? 322 LEU A HD23 1 c 
ATOM   1965 N N    . ASP A 1 155 ? 10.43   2.402   16.322  1     17.874 ? 323 ASP A N    1 ? 
ATOM   1966 C CA   . ASP A 1 155 ? 10.121  2.046   14.941  1     17.329 ? 323 ASP A CA   1 ? 
ATOM   1967 C C    . ASP A 1 155 ? 10.02   0.539   14.789  1     17.216 ? 323 ASP A C    1 ? 
ATOM   1968 O O    . ASP A 1 155 ? 10.344  -0.259  15.673  1     18.233 ? 323 ASP A O    1 ? 
ATOM   1969 C CB   . ASP A 1 155 ? 11.106  2.707   13.991  1     17.784 ? 323 ASP A CB   1 ? 
ATOM   1970 C CG   . ASP A 1 155 ? 10.682  2.73    12.522  1     19.275 ? 323 ASP A CG   1 ? 
ATOM   1971 O OD1  . ASP A 1 155 ? 9.475   2.626   12.281  1     17.565 ? 323 ASP A OD1  1 ? 
ATOM   1972 O OD2  . ASP A 1 155 ? 11.585  2.788   11.628  1     21.581 ? 323 ASP A OD2  1 ? 
ATOM   1973 H H    . ASP A 1 155 ? 11.273  2.258   16.644  1     17.739 ? 323 ASP A H    1 c 
ATOM   1974 H HA   . ASP A 1 155 ? 9.242   2.427   14.721  1     17.504 ? 323 ASP A HA   1 c 
ATOM   1975 H HB2  . ASP A 1 155 ? 11.236  3.632   14.285  1     18.003 ? 323 ASP A HB2  1 c 
ATOM   1976 H HB3  . ASP A 1 155 ? 11.967  2.244   14.056  1     18.006 ? 323 ASP A HB3  1 c 
ATOM   1977 N N    . MET A 1 156 ? 9.444   0.153   13.654  1     16.097 ? 324 MET A N    1 ? 
ATOM   1978 C CA   . MET A 1 156 ? 9.198   -1.215  13.249  1     16.63  ? 324 MET A CA   1 ? 
ATOM   1979 C C    . MET A 1 156 ? 8.17    -1.863  14.187  1     17.06  ? 324 MET A C    1 ? 
ATOM   1980 O O    . MET A 1 156 ? 8.162   -3.072  14.317  1     18.46  ? 324 MET A O    1 ? 
ATOM   1981 C CB   . MET A 1 156 ? 10.474  -2.032  13.058  1     16.519 ? 324 MET A CB   1 ? 
ATOM   1982 C CG   . MET A 1 156 ? 11.387  -1.444  11.974  1     20.949 ? 324 MET A CG   1 ? 
ATOM   1983 S SD   . MET A 1 156 ? 10.556  -1.362  10.381  1     23.11  ? 324 MET A SD   1 ? 
ATOM   1984 C CE   . MET A 1 156 ? 10.291  -3.078  9.917   1     26.243 ? 324 MET A CE   1 ? 
ATOM   1985 H H    . MET A 1 156 ? 9.147   0.807   13.09   1     16.516 ? 324 MET A H    1 c 
ATOM   1986 H HA   . MET A 1 156 ? 8.746   -1.161  12.371  1     16.627 ? 324 MET A HA   1 c 
ATOM   1987 H HB2  . MET A 1 156 ? 10.962  -2.07   13.907  1     17.473 ? 324 MET A HB2  1 c 
ATOM   1988 H HB3  . MET A 1 156 ? 10.231  -2.949  12.807  1     17.541 ? 324 MET A HB3  1 c 
ATOM   1989 H HG2  . MET A 1 156 ? 11.666  -0.544  12.235  1     20.153 ? 324 MET A HG2  1 c 
ATOM   1990 H HG3  . MET A 1 156 ? 12.189  -1.998  11.887  1     20.171 ? 324 MET A HG3  1 c 
ATOM   1991 H HE1  . MET A 1 156 ? 9.922   -3.118  9.016   1     25.457 ? 324 MET A HE1  1 c 
ATOM   1992 H HE2  . MET A 1 156 ? 11.14   -3.556  9.942   1     25.419 ? 324 MET A HE2  1 c 
ATOM   1993 H HE3  . MET A 1 156 ? 9.667   -3.491  10.542  1     25.367 ? 324 MET A HE3  1 c 
ATOM   1994 N N    . VAL A 1 157 ? 7.275   -1.049  14.756  1     16.879 ? 325 VAL A N    1 ? 
ATOM   1995 C CA   . VAL A 1 157 ? 6.007   -1.544  15.269  1     14.909 ? 325 VAL A CA   1 ? 
ATOM   1996 C C    . VAL A 1 157 ? 5.262   -2.297  14.16   1     16.983 ? 325 VAL A C    1 ? 
ATOM   1997 O O    . VAL A 1 157 ? 4.597   -3.306  14.421  1     16.654 ? 325 VAL A O    1 ? 
ATOM   1998 C CB   . VAL A 1 157 ? 5.19    -0.378  15.848  1     15.779 ? 325 VAL A CB   1 ? 
ATOM   1999 C CG1  . VAL A 1 157 ? 3.884   -0.867  16.458  1     18.606 ? 325 VAL A CG1  1 ? 
ATOM   2000 C CG2  . VAL A 1 157 ? 5.932   0.396   16.922  1     17.711 ? 325 VAL A CG2  1 ? 
ATOM   2001 H H    . VAL A 1 157 ? 7.441   -0.152  14.794  1     16.464 ? 325 VAL A H    1 c 
ATOM   2002 H HA   . VAL A 1 157 ? 6.198   -2.173  15.992  1     15.807 ? 325 VAL A HA   1 c 
ATOM   2003 H HB   . VAL A 1 157 ? 4.98    0.236   15.106  1     16.449 ? 325 VAL A HB   1 c 
ATOM   2004 H HG11 . VAL A 1 157 ? 4.076   -1.489  17.178  1     17.712 ? 325 VAL A HG11 1 c 
ATOM   2005 H HG12 . VAL A 1 157 ? 3.35    -1.312  15.78   1     17.711 ? 325 VAL A HG12 1 c 
ATOM   2006 H HG13 . VAL A 1 157 ? 3.387   -0.11   16.811  1     17.714 ? 325 VAL A HG13 1 c 
ATOM   2007 H HG21 . VAL A 1 157 ? 5.304   0.94    17.428  1     17.129 ? 325 VAL A HG21 1 c 
ATOM   2008 H HG22 . VAL A 1 157 ? 6.593   0.974   16.509  1     17.118 ? 325 VAL A HG22 1 c 
ATOM   2009 H HG23 . VAL A 1 157 ? 6.376   -0.226  17.522  1     17.118 ? 325 VAL A HG23 1 c 
ATOM   2010 N N    . VAL A 1 158 ? 5.298   -1.755  12.936  1     15.966 ? 326 VAL A N    1 ? 
ATOM   2011 C CA   . VAL A 1 158 ? 4.651   -2.372  11.782  1     15.999 ? 326 VAL A CA   1 ? 
ATOM   2012 C C    . VAL A 1 158 ? 5.089   -3.819  11.538  1     15.937 ? 326 VAL A C    1 ? 
ATOM   2013 O O    . VAL A 1 158 ? 4.454   -4.506  10.732  1     15.786 ? 326 VAL A O    1 ? 
ATOM   2014 C CB   . VAL A 1 158 ? 4.905   -1.585  10.467  1     17.763 ? 326 VAL A CB   1 ? 
ATOM   2015 C CG1  . VAL A 1 158 ? 4.239   -0.232  10.452  1     22.232 ? 326 VAL A CG1  1 ? 
ATOM   2016 C CG2  . VAL A 1 158 ? 6.378   -1.465  10.128  1     20.115 ? 326 VAL A CG2  1 ? 
ATOM   2017 H H    . VAL A 1 158 ? 5.719   -0.952  12.822  1     16.318 ? 326 VAL A H    1 c 
ATOM   2018 H HA   . VAL A 1 158 ? 3.689   -2.375  11.948  1     16.29  ? 326 VAL A HA   1 c 
ATOM   2019 H HB   . VAL A 1 158 ? 4.489   -2.105  9.74    1     18.591 ? 326 VAL A HB   1 c 
ATOM   2020 H HG11 . VAL A 1 158 ? 4.574   0.304   11.189  1     20.756 ? 326 VAL A HG11 1 c 
ATOM   2021 H HG12 . VAL A 1 158 ? 3.277   -0.343  10.545  1     20.773 ? 326 VAL A HG12 1 c 
ATOM   2022 H HG13 . VAL A 1 158 ? 4.431   0.217   9.612   1     20.842 ? 326 VAL A HG13 1 c 
ATOM   2023 H HG21 . VAL A 1 158 ? 6.488   -0.868  9.369   1     19.393 ? 326 VAL A HG21 1 c 
ATOM   2024 H HG22 . VAL A 1 158 ? 6.734   -2.34   9.9     1     19.359 ? 326 VAL A HG22 1 c 
ATOM   2025 H HG23 . VAL A 1 158 ? 6.863   -1.109  10.89   1     19.324 ? 326 VAL A HG23 1 c 
ATOM   2026 N N    . THR A 1 159 ? 6.207   -4.275  12.103  1     17.7   ? 327 THR A N    1 ? 
ATOM   2027 C CA   . THR A 1 159 ? 6.583   -5.674  12.047  1     16.998 ? 327 THR A CA   1 ? 
ATOM   2028 C C    . THR A 1 159 ? 5.391   -6.572  12.366  1     17.502 ? 327 THR A C    1 ? 
ATOM   2029 O O    . THR A 1 159 ? 5.259   -7.617  11.738  1     16.882 ? 327 THR A O    1 ? 
ATOM   2030 C CB   . THR A 1 159 ? 7.751   -5.97   12.994  1     18.931 ? 327 THR A CB   1 ? 
ATOM   2031 O OG1  . THR A 1 159 ? 8.879   -5.302  12.429  1     18.785 ? 327 THR A OG1  1 ? 
ATOM   2032 C CG2  . THR A 1 159 ? 8.079   -7.448  13.118  1     19.082 ? 327 THR A CG2  1 ? 
ATOM   2033 H H    . THR A 1 159 ? 6.784   -3.687  12.498  1     17.108 ? 327 THR A H    1 c 
ATOM   2034 H HA   . THR A 1 159 ? 6.877   -5.869  11.13   1     17.571 ? 327 THR A HA   1 c 
ATOM   2035 H HB   . THR A 1 159 ? 7.56    -5.601  13.889  1     18.565 ? 327 THR A HB   1 c 
ATOM   2036 H HG21 . THR A 1 159 ? 8.861   -7.561  13.681  1     19.037 ? 327 THR A HG21 1 c 
ATOM   2037 H HG22 . THR A 1 159 ? 8.261   -7.815  12.237  1     19.022 ? 327 THR A HG22 1 c 
ATOM   2038 H HG23 . THR A 1 159 ? 7.33    -7.92   13.518  1     19.01  ? 327 THR A HG23 1 c 
ATOM   2039 N N    . TYR A 1 160 ? 4.502   -6.151  13.275  1     15.615 ? 328 TYR A N    1 ? 
ATOM   2040 C CA   . TYR A 1 160 ? 3.409   -7.034  13.683  1     15.795 ? 328 TYR A CA   1 ? 
ATOM   2041 C C    . TYR A 1 160 ? 2.566   -7.46   12.483  1     17.662 ? 328 TYR A C    1 ? 
ATOM   2042 O O    . TYR A 1 160 ? 1.948   -8.53   12.503  1     17.08  ? 328 TYR A O    1 ? 
ATOM   2043 C CB   . TYR A 1 160 ? 2.518   -6.433  14.789  1     16.87  ? 328 TYR A CB   1 ? 
ATOM   2044 C CG   . TYR A 1 160 ? 1.317   -5.694  14.241  1     17.3   ? 328 TYR A CG   1 ? 
ATOM   2045 C CD1  . TYR A 1 160 ? 1.408   -4.343  13.907  1     19.234 ? 328 TYR A CD1  1 ? 
ATOM   2046 C CD2  . TYR A 1 160 ? 0.094   -6.347  14.069  1     16.552 ? 328 TYR A CD2  1 ? 
ATOM   2047 C CE1  . TYR A 1 160 ? 0.313   -3.658  13.389  1     17.502 ? 328 TYR A CE1  1 ? 
ATOM   2048 C CE2  . TYR A 1 160 ? -0.99   -5.676  13.546  1     17.748 ? 328 TYR A CE2  1 ? 
ATOM   2049 C CZ   . TYR A 1 160 ? -0.876  -4.349  13.182  1     17.856 ? 328 TYR A CZ   1 ? 
ATOM   2050 O OH   . TYR A 1 160 ? -1.995  -3.71   12.747  1     17.6   ? 328 TYR A OH   1 ? 
ATOM   2051 H H    . TYR A 1 160 ? 4.588   -5.333  13.673  1     16.113 ? 328 TYR A H    1 c 
ATOM   2052 H HA   . TYR A 1 160 ? 3.824   -7.856  14.057  1     16.289 ? 328 TYR A HA   1 c 
ATOM   2053 H HB2  . TYR A 1 160 ? 2.207   -7.161  15.372  1     16.717 ? 328 TYR A HB2  1 c 
ATOM   2054 H HB3  . TYR A 1 160 ? 3.057   -5.815  15.331  1     16.714 ? 328 TYR A HB3  1 c 
ATOM   2055 H HD1  . TYR A 1 160 ? 2.226   -3.891  14.017  1     18.318 ? 328 TYR A HD1  1 c 
ATOM   2056 H HD2  . TYR A 1 160 ? 0.019   -7.264  14.281  1     17.019 ? 328 TYR A HD2  1 c 
ATOM   2057 H HE1  . TYR A 1 160 ? 0.382   -2.746  13.161  1     17.956 ? 328 TYR A HE1  1 c 
ATOM   2058 H HE2  . TYR A 1 160 ? -1.811  -6.124  13.431  1     17.49  ? 328 TYR A HE2  1 c 
ATOM   2059 N N    . GLU A 1 161 ? 2.481   -6.597  11.451  1     17.427 ? 329 GLU A N    1 ? 
ATOM   2060 C CA   . GLU A 1 161 ? 1.623   -6.89   10.305  1     19.315 ? 329 GLU A CA   1 ? 
ATOM   2061 C C    . GLU A 1 161 ? 2.417   -7.29   9.063   1     20.476 ? 329 GLU A C    1 ? 
ATOM   2062 O O    . GLU A 1 161 ? 1.804   -7.68   8.064   1     20.601 ? 329 GLU A O    1 ? 
ATOM   2063 C CB   . GLU A 1 161 ? 0.628   -5.763  10.004  1     20.658 ? 329 GLU A CB   1 ? 
ATOM   2064 C CG   . GLU A 1 161 ? 1.264   -4.537  9.371   1     22.439 ? 329 GLU A CG   1 ? 
ATOM   2065 C CD   . GLU A 1 161 ? 0.268   -3.434  8.985   1     23.022 ? 329 GLU A CD   1 ? 
ATOM   2066 O OE1  . GLU A 1 161 ? -0.942  -3.647  9.009   1     26.704 ? 329 GLU A OE1  1 ? 
ATOM   2067 O OE2  . GLU A 1 161 ? 0.731   -2.345  8.64    1     23.362 ? 329 GLU A OE2  1 ? 
ATOM   2068 H H    . GLU A 1 161 ? 2.922   -5.797  11.479  1     17.854 ? 329 GLU A H    1 c 
ATOM   2069 H HA   . GLU A 1 161 ? 1.06    -7.663  10.541  1     19.364 ? 329 GLU A HA   1 c 
ATOM   2070 H HB2  . GLU A 1 161 ? -0.063  -6.11   9.402   1     20.759 ? 329 GLU A HB2  1 c 
ATOM   2071 H HB3  . GLU A 1 161 ? 0.19    -5.5    10.838  1     20.725 ? 329 GLU A HB3  1 c 
ATOM   2072 H HG2  . GLU A 1 161 ? 1.916   -4.159  9.997   1     22.106 ? 329 GLU A HG2  1 c 
ATOM   2073 H HG3  . GLU A 1 161 ? 1.75    -4.805  8.563   1     22.132 ? 329 GLU A HG3  1 c 
ATOM   2074 N N    . GLU A 1 162 ? 3.741   -7.142  9.09    1     18.741 ? 330 GLU A N    1 ? 
ATOM   2075 C CA   . GLU A 1 162 ? 4.586   -7.363  7.928   1     17.427 ? 330 GLU A CA   1 ? 
ATOM   2076 C C    . GLU A 1 162 ? 5.205   -8.752  7.892   1     20.189 ? 330 GLU A C    1 ? 
ATOM   2077 O O    . GLU A 1 162 ? 5.728   -9.174  6.845   1     17.916 ? 330 GLU A O    1 ? 
ATOM   2078 C CB   . GLU A 1 162 ? 5.669   -6.295  7.849   1     19.484 ? 330 GLU A CB   1 ? 
ATOM   2079 C CG   . GLU A 1 162 ? 5.058   -4.94   7.503   1     20.836 ? 330 GLU A CG   1 ? 
ATOM   2080 C CD   . GLU A 1 162 ? 6.015   -3.813  7.239   1     20.806 ? 330 GLU A CD   1 ? 
ATOM   2081 O OE1  . GLU A 1 162 ? 7.25    -3.987  7.324   1     23.948 ? 330 GLU A OE1  1 ? 
ATOM   2082 O OE2  . GLU A 1 162 ? 5.446   -2.726  6.951   1     23.747 ? 330 GLU A OE2  1 ? 
ATOM   2083 H H    . GLU A 1 162 ? 4.144   -6.879  9.865   1     18.805 ? 330 GLU A H    1 c 
ATOM   2084 H HA   . GLU A 1 162 ? 4.025   -7.266  7.117   1     18.586 ? 330 GLU A HA   1 c 
ATOM   2085 H HB2  . GLU A 1 162 ? 6.143   -6.249  8.705   1     19.281 ? 330 GLU A HB2  1 c 
ATOM   2086 H HB3  . GLU A 1 162 ? 6.313   -6.548  7.158   1     19.289 ? 330 GLU A HB3  1 c 
ATOM   2087 H HG2  . GLU A 1 162 ? 4.495   -5.047  6.707   1     20.493 ? 330 GLU A HG2  1 c 
ATOM   2088 H HG3  . GLU A 1 162 ? 4.464   -4.669  8.232   1     20.472 ? 330 GLU A HG3  1 c 
ATOM   2089 N N    . ILE A 1 163 ? 5.155   -9.455  9.035   1     17.754 ? 331 ILE A N    1 ? 
ATOM   2090 C CA   . ILE A 1 163 ? 5.598   -10.81  9.097   1     17.395 ? 331 ILE A CA   1 ? 
ATOM   2091 C C    . ILE A 1 163 ? 4.431   -11.743 8.789   1     18.855 ? 331 ILE A C    1 ? 
ATOM   2092 O O    . ILE A 1 163 ? 3.271   -11.344 8.848   1     17.799 ? 331 ILE A O    1 ? 
ATOM   2093 C CB   . ILE A 1 163 ? 6.19    -11.103 10.479  1     18.382 ? 331 ILE A CB   1 ? 
ATOM   2094 C CG1  . ILE A 1 163 ? 5.16    -11.004 11.604  1     18.756 ? 331 ILE A CG1  1 ? 
ATOM   2095 C CG2  . ILE A 1 163 ? 7.395   -10.199 10.683  1     17.286 ? 331 ILE A CG2  1 ? 
ATOM   2096 C CD1  . ILE A 1 163 ? 5.717   -11.168 13.023  1     21.105 ? 331 ILE A CD1  1 ? 
ATOM   2097 H H    . ILE A 1 163 ? 4.844   -9.057  9.794   1     18.235 ? 331 ILE A H    1 c 
ATOM   2098 H HA   . ILE A 1 163 ? 6.295   -10.94  8.429   1     17.909 ? 331 ILE A HA   1 c 
ATOM   2099 H HB   . ILE A 1 163 ? 6.516   -12.023 10.468  1     18.046 ? 331 ILE A HB   1 c 
ATOM   2100 H HG12 . ILE A 1 163 ? 4.712   -10.138 11.55   1     19.151 ? 331 ILE A HG12 1 c 
ATOM   2101 H HG13 . ILE A 1 163 ? 4.48    -11.694 11.465  1     19.173 ? 331 ILE A HG13 1 c 
ATOM   2102 H HG21 . ILE A 1 163 ? 7.932   -10.532 11.421  1     17.62  ? 331 ILE A HG21 1 c 
ATOM   2103 H HG22 . ILE A 1 163 ? 7.096   -9.298  10.885  1     17.613 ? 331 ILE A HG22 1 c 
ATOM   2104 H HG23 . ILE A 1 163 ? 7.935   -10.184 9.875   1     17.608 ? 331 ILE A HG23 1 c 
ATOM   2105 H HD11 . ILE A 1 163 ? 6.219   -12.002 13.084  1     20.383 ? 331 ILE A HD11 1 c 
ATOM   2106 H HD12 . ILE A 1 163 ? 4.977   -11.191 13.659  1     20.384 ? 331 ILE A HD12 1 c 
ATOM   2107 H HD13 . ILE A 1 163 ? 6.305   -10.42  13.24   1     20.373 ? 331 ILE A HD13 1 c 
ATOM   2108 N N    . PRO A 1 164 ? 4.713   -13.023 8.454   1     18.946 ? 332 PRO A N    1 ? 
ATOM   2109 C CA   . PRO A 1 164 ? 3.619   -13.978 8.235   1     17.937 ? 332 PRO A CA   1 ? 
ATOM   2110 C C    . PRO A 1 164 ? 2.715   -14.063 9.461   1     19.279 ? 332 PRO A C    1 ? 
ATOM   2111 O O    . PRO A 1 164 ? 3.21    -14.043 10.585  1     19.552 ? 332 PRO A O    1 ? 
ATOM   2112 C CB   . PRO A 1 164 ? 4.377   -15.258 7.929   1     18.011 ? 332 PRO A CB   1 ? 
ATOM   2113 C CG   . PRO A 1 164 ? 5.678   -14.756 7.327   1     17.814 ? 332 PRO A CG   1 ? 
ATOM   2114 C CD   . PRO A 1 164 ? 6.043   -13.603 8.26    1     17.065 ? 332 PRO A CD   1 ? 
ATOM   2115 H HA   . PRO A 1 164 ? 3.1     -13.697 7.442   1     18.369 ? 332 PRO A HA   1 c 
ATOM   2116 H HB2  . PRO A 1 164 ? 4.543   -15.777 8.75    1     17.957 ? 332 PRO A HB2  1 c 
ATOM   2117 H HB3  . PRO A 1 164 ? 3.881   -15.817 7.285   1     17.951 ? 332 PRO A HB3  1 c 
ATOM   2118 H HG2  . PRO A 1 164 ? 6.368   -15.452 7.333   1     17.687 ? 332 PRO A HG2  1 c 
ATOM   2119 H HG3  . PRO A 1 164 ? 5.545   -14.436 6.413   1     17.687 ? 332 PRO A HG3  1 c 
ATOM   2120 H HD2  . PRO A 1 164 ? 6.428   -13.927 9.101   1     17.666 ? 332 PRO A HD2  1 c 
ATOM   2121 H HD3  . PRO A 1 164 ? 6.66    -12.977 7.824   1     17.655 ? 332 PRO A HD3  1 c 
ATOM   2122 N N    . ALA A 1 165 ? 1.402   -14.183 9.212   1     16.934 ? 333 ALA A N    1 ? 
ATOM   2123 C CA   . ALA A 1 165 ? 0.396   -14.131 10.255  1     19.794 ? 333 ALA A CA   1 ? 
ATOM   2124 C C    . ALA A 1 165 ? 0.576   -15.306 11.212  1     22.381 ? 333 ALA A C    1 ? 
ATOM   2125 O O    . ALA A 1 165 ? 0.199   -15.194 12.37   1     21.606 ? 333 ALA A O    1 ? 
ATOM   2126 C CB   . ALA A 1 165 ? -0.999  -14.084 9.685   1     20.276 ? 333 ALA A CB   1 ? 
ATOM   2127 H H    . ALA A 1 165 ? 1.126   -14.309 8.35    1     18.109 ? 333 ALA A H    1 c 
ATOM   2128 H HA   . ALA A 1 165 ? 0.549   -13.295 10.776  1     19.723 ? 333 ALA A HA   1 c 
ATOM   2129 H HB1  . ALA A 1 165 ? -1.097  -13.295 9.126   1     20.132 ? 333 ALA A HB1  1 c 
ATOM   2130 H HB2  . ALA A 1 165 ? -1.161  -14.879 9.15    1     20.132 ? 333 ALA A HB2  1 c 
ATOM   2131 H HB3  . ALA A 1 165 ? -1.647  -14.046 10.409  1     20.132 ? 333 ALA A HB3  1 c 
ATOM   2132 N N    . ASN A 1 166 ? 1.244   -16.382 10.763  1     20.891 ? 334 ASN A N    1 ? 
ATOM   2133 C CA   . ASN A 1 166 ? 1.428   -17.567 11.587  1     21.816 ? 334 ASN A CA   1 ? 
ATOM   2134 C C    . ASN A 1 166 ? 2.803   -17.611 12.258  1     20.001 ? 334 ASN A C    1 ? 
ATOM   2135 O O    . ASN A 1 166 ? 3.209   -18.659 12.791  1     21.491 ? 334 ASN A O    1 ? 
ATOM   2136 C CB   . ASN A 1 166 ? 1.185   -18.822 10.75   1     21.995 ? 334 ASN A CB   1 ? 
ATOM   2137 C CG   . ASN A 1 166 ? 2.208   -19.006 9.663   1     22.671 ? 334 ASN A CG   1 ? 
ATOM   2138 O OD1  . ASN A 1 166 ? 3.246   -18.323 9.637   1     25.044 ? 334 ASN A OD1  1 ? 
ATOM   2139 N ND2  . ASN A 1 166 ? 1.963   -19.976 8.786   1     24.631 ? 334 ASN A ND2  1 ? 
ATOM   2140 H H    . ASN A 1 166 ? 1.564   -16.393 9.908   1     21.391 ? 334 ASN A H    1 c 
ATOM   2141 H HA   . ASN A 1 166 ? 0.747   -17.56  12.296  1     21.331 ? 334 ASN A HA   1 c 
ATOM   2142 H HB2  . ASN A 1 166 ? 1.198   -19.605 11.336  1     22.105 ? 334 ASN A HB2  1 c 
ATOM   2143 H HB3  . ASN A 1 166 ? 0.297   -18.766 10.344  1     22.108 ? 334 ASN A HB3  1 c 
ATOM   2144 H HD21 . ASN A 1 166 ? 2.629   -20.481 8.488   1     24.007 ? 334 ASN A HD21 1 c 
ATOM   2145 H HD22 . ASN A 1 166 ? 1.135   -20.116 8.501   1     23.997 ? 334 ASN A HD22 1 c 
ATOM   2146 N N    . SER A 1 167 ? 3.49    -16.47  12.352  1     20.355 ? 335 SER A N    1 ? 
ATOM   2147 C CA   . SER A 1 167 ? 4.881   -16.448 12.79   1     20.816 ? 335 SER A CA   1 ? 
ATOM   2148 C C    . SER A 1 167 ? 5.041   -16.945 14.237  1     20.625 ? 335 SER A C    1 ? 
ATOM   2149 O O    . SER A 1 167 ? 6.107   -17.423 14.576  1     22.519 ? 335 SER A O    1 ? 
ATOM   2150 C CB   . SER A 1 167 ? 5.475   -15.091 12.689  1     21.086 ? 335 SER A CB   1 ? 
ATOM   2151 O OG   . SER A 1 167 ? 5.522   -14.639 11.348  1     19.86  ? 335 SER A OG   1 ? 
ATOM   2152 H H    . SER A 1 167 ? 3.083   -15.676 12.158  1     20.401 ? 335 SER A H    1 c 
ATOM   2153 H HA   . SER A 1 167 ? 5.395   -17.055 12.2    1     20.809 ? 335 SER A HA   1 c 
ATOM   2154 H HB2  . SER A 1 167 ? 4.945   -14.468 13.221  1     20.727 ? 335 SER A HB2  1 c 
ATOM   2155 H HB3  . SER A 1 167 ? 6.381   -15.107 13.055  1     20.727 ? 335 SER A HB3  1 c 
ATOM   2156 N N    . ALA A 1 168 ? 4.025   -16.702 15.086  1     19.498 ? 336 ALA A N    1 ? 
ATOM   2157 C CA   . ALA A 1 168 ? 4.048   -17.16  16.473  1     21.227 ? 336 ALA A CA   1 ? 
ATOM   2158 C C    . ALA A 1 168 ? 3.2     -18.407 16.65   1     25.571 ? 336 ALA A C    1 ? 
ATOM   2159 O O    . ALA A 1 168 ? 2.826   -18.748 17.778  1     26.696 ? 336 ALA A O    1 ? 
ATOM   2160 C CB   . ALA A 1 168 ? 3.592   -16.028 17.387  1     20.471 ? 336 ALA A CB   1 ? 
ATOM   2161 H H    . ALA A 1 168 ? 3.302   -16.223 14.798  1     20.147 ? 336 ALA A H    1 c 
ATOM   2162 H HA   . ALA A 1 168 ? 4.987   -17.396 16.711  1     21.476 ? 336 ALA A HA   1 c 
ATOM   2163 H HB1  . ALA A 1 168 ? 3.992   -15.191 17.096  1     20.688 ? 336 ALA A HB1  1 c 
ATOM   2164 H HB2  . ALA A 1 168 ? 2.624   -15.949 17.352  1     20.713 ? 336 ALA A HB2  1 c 
ATOM   2165 H HB3  . ALA A 1 168 ? 3.866   -16.214 18.301  1     20.694 ? 336 ALA A HB3  1 c 
ATOM   2166 N N    . GLY A 1 169 ? 2.863   -19.075 15.536  1     24.575 ? 337 GLY A N    1 ? 
ATOM   2167 C CA   . GLY A 1 169 ? 1.928   -20.186 15.547  1     24.222 ? 337 GLY A CA   1 ? 
ATOM   2168 C C    . GLY A 1 169 ? 0.505   -19.782 15.91   1     25.827 ? 337 GLY A C    1 ? 
ATOM   2169 O O    . GLY A 1 169 ? -0.267  -20.627 16.368  1     26.469 ? 337 GLY A O    1 ? 
ATOM   2170 H H    . GLY A 1 169 ? 3.251   -18.851 14.742  1     24.599 ? 337 GLY A H    1 c 
ATOM   2171 H HA2  . GLY A 1 169 ? 1.927   -20.605 14.654  1     24.659 ? 337 GLY A HA2  1 c 
ATOM   2172 H HA3  . GLY A 1 169 ? 2.247   -20.86  16.191  1     24.667 ? 337 GLY A HA3  1 c 
ATOM   2173 N N    . THR A 1 170 ? 0.15    -18.496 15.742  1     24.168 ? 338 THR A N    1 ? 
ATOM   2174 C CA   . THR A 1 170 ? -1.172  -18.005 16.078  1     23.77  ? 338 THR A CA   1 ? 
ATOM   2175 C C    . THR A 1 170 ? -1.749  -17.292 14.854  1     26.021 ? 338 THR A C    1 ? 
ATOM   2176 O O    . THR A 1 170 ? -1.905  -17.92  13.809  1     23.834 ? 338 THR A O    1 ? 
ATOM   2177 C CB   . THR A 1 170 ? -1.081  -17.114 17.325  1     25.245 ? 338 THR A CB   1 ? 
ATOM   2178 O OG1  . THR A 1 170 ? -0.115  -16.086 17.048  1     20.079 ? 338 THR A OG1  1 ? 
ATOM   2179 C CG2  . THR A 1 170 ? -0.593  -17.904 18.522  1     25.42  ? 338 THR A CG2  1 ? 
ATOM   2180 H H    . THR A 1 170 ? 0.75    -17.908 15.383  1     24.475 ? 338 THR A H    1 c 
ATOM   2181 H HA   . THR A 1 170 ? -1.749  -18.769 16.289  1     24.625 ? 338 THR A HA   1 c 
ATOM   2182 H HB   . THR A 1 170 ? -1.957  -16.713 17.54   1     23.89  ? 338 THR A HB   1 c 
ATOM   2183 H HG21 . THR A 1 170 ? -0.761  -17.398 19.335  1     25.358 ? 338 THR A HG21 1 c 
ATOM   2184 H HG22 . THR A 1 170 ? 0.36    -18.069 18.436  1     25.33  ? 338 THR A HG22 1 c 
ATOM   2185 H HG23 . THR A 1 170 ? -1.065  -18.752 18.566  1     25.355 ? 338 THR A HG23 1 c 
ATOM   2186 N N    . ASN A 1 171 ? -2.064  -15.999 14.98   1     21.818 ? 339 ASN A N    1 ? 
ATOM   2187 C CA   . ASN A 1 171 ? -2.673  -15.241 13.901  1     20.788 ? 339 ASN A CA   1 ? 
ATOM   2188 C C    . ASN A 1 171 ? -2.316  -13.767 14.05   1     19.629 ? 339 ASN A C    1 ? 
ATOM   2189 O O    . ASN A 1 171 ? -1.584  -13.362 14.974  1     18.961 ? 339 ASN A O    1 ? 
ATOM   2190 C CB   . ASN A 1 171 ? -4.183  -15.499 13.843  1     20.222 ? 339 ASN A CB   1 ? 
ATOM   2191 C CG   . ASN A 1 171 ? -4.912  -15.038 15.085  1     26.189 ? 339 ASN A CG   1 ? 
ATOM   2192 O OD1  . ASN A 1 171 ? -4.368  -14.286 15.912  1     24.611 ? 339 ASN A OD1  1 ? 
ATOM   2193 N ND2  . ASN A 1 171 ? -6.158  -15.478 15.226  1     28.982 ? 339 ASN A ND2  1 ? 
ATOM   2194 H H    . ASN A 1 171 ? -1.876  -15.561 15.759  1     22.525 ? 339 ASN A H    1 c 
ATOM   2195 H HA   . ASN A 1 171 ? -2.294  -15.557 13.051  1     20.704 ? 339 ASN A HA   1 c 
ATOM   2196 H HB2  . ASN A 1 171 ? -4.561  -15.045 13.066  1     21.592 ? 339 ASN A HB2  1 c 
ATOM   2197 H HB3  . ASN A 1 171 ? -4.335  -16.458 13.729  1     21.618 ? 339 ASN A HB3  1 c 
ATOM   2198 H HD21 . ASN A 1 171 ? -6.625  -15.257 15.947  1     28.048 ? 339 ASN A HD21 1 c 
ATOM   2199 H HD22 . ASN A 1 171 ? -6.524  -15.992 14.601  1     28.018 ? 339 ASN A HD22 1 c 
ATOM   2200 N N    . ARG A 1 172 ? -2.851  -12.956 13.13   1     19.898 ? 340 ARG A N    1 ? 
ATOM   2201 C CA   . ARG A 1 172 ? -2.445  -11.563 13.049  1     17.949 ? 340 ARG A CA   1 ? 
ATOM   2202 C C    . ARG A 1 172 ? -2.87   -10.823 14.319  1     18.501 ? 340 ARG A C    1 ? 
ATOM   2203 O O    . ARG A 1 172 ? -2.141  -9.971  14.784  1     21.324 ? 340 ARG A O    1 ? 
ATOM   2204 C CB   . ARG A 1 172 ? -3.072  -10.86  11.831  1     19.33  ? 340 ARG A CB   1 ? 
ATOM   2205 C CG   . ARG A 1 172 ? -2.698  -9.396  11.663  1     19.341 ? 340 ARG A CG   1 ? 
ATOM   2206 C CD   . ARG A 1 172 ? -1.203  -9.172  11.421  1     20.144 ? 340 ARG A CD   1 ? 
ATOM   2207 N NE   . ARG A 1 172 ? -0.85   -9.635  10.072  1     18.315 ? 340 ARG A NE   1 ? 
ATOM   2208 C CZ   . ARG A 1 172 ? 0.243   -10.315 9.736   1     19.466 ? 340 ARG A CZ   1 ? 
ATOM   2209 N NH1  . ARG A 1 172 ? 1.262   -10.454 10.57   1     19.33  ? 340 ARG A NH1  1 ? 
ATOM   2210 N NH2  . ARG A 1 172 ? 0.33    -10.809 8.511   1     19.246 ? 340 ARG A NH2  1 ? 
ATOM   2211 H H    . ARG A 1 172 ? -3.462  -13.273 12.529  1     19.41  ? 340 ARG A H    1 c 
ATOM   2212 H HA   . ARG A 1 172 ? -1.459  -11.533 12.977  1     18.682 ? 340 ARG A HA   1 c 
ATOM   2213 H HB2  . ARG A 1 172 ? -2.805  -11.345 11.021  1     19.011 ? 340 ARG A HB2  1 c 
ATOM   2214 H HB3  . ARG A 1 172 ? -4.049  -10.926 11.904  1     19.011 ? 340 ARG A HB3  1 c 
ATOM   2215 H HG2  . ARG A 1 172 ? -3.199  -9.026  10.903  1     19.515 ? 340 ARG A HG2  1 c 
ATOM   2216 H HG3  . ARG A 1 172 ? -2.97   -8.894  12.461  1     19.52  ? 340 ARG A HG3  1 c 
ATOM   2217 H HD2  . ARG A 1 172 ? -1.002  -8.217  11.499  1     19.514 ? 340 ARG A HD2  1 c 
ATOM   2218 H HD3  . ARG A 1 172 ? -0.672  -9.65   12.087  1     19.503 ? 340 ARG A HD3  1 c 
ATOM   2219 H HE   . ARG A 1 172 ? -1.406  -9.445  9.428   1     19.005 ? 340 ARG A HE   1 c 
ATOM   2220 H HH11 . ARG A 1 172 ? 1.501   -9.794  11.103  1     19.368 ? 340 ARG A HH11 1 c 
ATOM   2221 H HH12 . ARG A 1 172 ? 1.706   -11.218 10.587  1     19.373 ? 340 ARG A HH12 1 c 
ATOM   2222 H HH21 . ARG A 1 172 ? -0.378  -11.187 8.139   1     19.311 ? 340 ARG A HH21 1 c 
ATOM   2223 H HH22 . ARG A 1 172 ? 1.094   -10.76  8.071   1     19.313 ? 340 ARG A HH22 1 c 
ATOM   2224 N N    . ALA A 1 173 ? -4.06   -11.138 14.853  1     19.002 ? 341 ALA A N    1 ? 
ATOM   2225 C CA   . ALA A 1 173 ? -4.585  -10.407 16.006  1     21.706 ? 341 ALA A CA   1 ? 
ATOM   2226 C C    . ALA A 1 173 ? -3.691  -10.675 17.21   1     17.458 ? 341 ALA A C    1 ? 
ATOM   2227 O O    . ALA A 1 173 ? -3.476  -9.784  18.039  1     21.031 ? 341 ALA A O    1 ? 
ATOM   2228 C CB   . ALA A 1 173 ? -6.04   -10.797 16.278  1     20.895 ? 341 ALA A CB   1 ? 
ATOM   2229 H H    . ALA A 1 173 ? -4.561  -11.811 14.491  1     19.455 ? 341 ALA A H    1 c 
ATOM   2230 H HA   . ALA A 1 173 ? -4.544  -9.432  15.8    1     20.178 ? 341 ALA A HA   1 c 
ATOM   2231 H HB1  . ALA A 1 173 ? -6.576  -10.635 15.483  1     21.252 ? 341 ALA A HB1  1 c 
ATOM   2232 H HB2  . ALA A 1 173 ? -6.089  -11.739 16.511  1     21.159 ? 341 ALA A HB2  1 c 
ATOM   2233 H HB3  . ALA A 1 173 ? -6.389  -10.266 17.013  1     21.159 ? 341 ALA A HB3  1 c 
ATOM   2234 N N    . ASP A 1 174 ? -3.154  -11.894 17.303  1     18.542 ? 342 ASP A N    1 ? 
ATOM   2235 C CA   . ASP A 1 174 ? -2.284  -12.284 18.401  1     19.561 ? 342 ASP A CA   1 ? 
ATOM   2236 C C    . ASP A 1 174 ? -0.943  -11.567 18.274  1     18.921 ? 342 ASP A C    1 ? 
ATOM   2237 O O    . ASP A 1 174 ? -0.385  -11.117 19.283  1     19.55  ? 342 ASP A O    1 ? 
ATOM   2238 C CB   . ASP A 1 174 ? -2.099  -13.791 18.528  1     20.479 ? 342 ASP A CB   1 ? 
ATOM   2239 C CG   . ASP A 1 174 ? -1.183  -14.196 19.682  1     22.347 ? 342 ASP A CG   1 ? 
ATOM   2240 O OD1  . ASP A 1 174 ? -1.595  -13.982 20.842  1     24.487 ? 342 ASP A OD1  1 ? 
ATOM   2241 O OD2  . ASP A 1 174 ? -0.053  -14.666 19.41   1     20.955 ? 342 ASP A OD2  1 ? 
ATOM   2242 H H    . ASP A 1 174 ? -3.35   -12.519 16.665  1     18.536 ? 342 ASP A H    1 c 
ATOM   2243 H HA   . ASP A 1 174 ? -2.705  -11.988 19.238  1     19.483 ? 342 ASP A HA   1 c 
ATOM   2244 H HB2  . ASP A 1 174 ? -2.973  -14.212 18.661  1     20.774 ? 342 ASP A HB2  1 c 
ATOM   2245 H HB3  . ASP A 1 174 ? -1.721  -14.131 17.691  1     20.69  ? 342 ASP A HB3  1 c 
ATOM   2246 N N    . LEU A 1 175 ? -0.455  -11.441 17.016  1     20.407 ? 343 LEU A N    1 ? 
ATOM   2247 C CA   . LEU A 1 175 ? 0.764   -10.697 16.759  1     19.345 ? 343 LEU A CA   1 ? 
ATOM   2248 C C    . LEU A 1 175 ? 0.561   -9.244  17.185  1     19.094 ? 343 LEU A C    1 ? 
ATOM   2249 O O    . LEU A 1 175 ? 1.492   -8.642  17.732  1     16.962 ? 343 LEU A O    1 ? 
ATOM   2250 C CB   . LEU A 1 175 ? 1.206   -10.838 15.306  1     20.117 ? 343 LEU A CB   1 ? 
ATOM   2251 C CG   . LEU A 1 175 ? 1.668   -12.24  14.918  1     19.686 ? 343 LEU A CG   1 ? 
ATOM   2252 C CD1  . LEU A 1 175 ? 1.87    -12.3   13.412  1     19.69  ? 343 LEU A CD1  1 ? 
ATOM   2253 C CD2  . LEU A 1 175 ? 2.925   -12.711 15.673  1     21.358 ? 343 LEU A CD2  1 ? 
ATOM   2254 H H    . LEU A 1 175 ? -0.885  -11.842 16.316  1     19.796 ? 343 LEU A H    1 c 
ATOM   2255 H HA   . LEU A 1 175 ? 1.47    -11.077 17.339  1     19.634 ? 343 LEU A HA   1 c 
ATOM   2256 H HB2  . LEU A 1 175 ? 0.452   -10.585 14.726  1     19.841 ? 343 LEU A HB2  1 c 
ATOM   2257 H HB3  . LEU A 1 175 ? 1.945   -10.208 15.143  1     19.815 ? 343 LEU A HB3  1 c 
ATOM   2258 H HG   . LEU A 1 175 ? 0.938   -12.87  15.144  1     20.06  ? 343 LEU A HG   1 c 
ATOM   2259 H HD11 . LEU A 1 175 ? 1.036   -12.081 12.963  1     19.692 ? 343 LEU A HD11 1 c 
ATOM   2260 H HD12 . LEU A 1 175 ? 2.148   -13.195 13.156  1     19.697 ? 343 LEU A HD12 1 c 
ATOM   2261 H HD13 . LEU A 1 175 ? 2.554   -11.662 13.15   1     19.691 ? 343 LEU A HD13 1 c 
ATOM   2262 H HD21 . LEU A 1 175 ? 2.682   -12.974 16.576  1     20.843 ? 343 LEU A HD21 1 c 
ATOM   2263 H HD22 . LEU A 1 175 ? 3.572   -11.986 15.711  1     20.85  ? 343 LEU A HD22 1 c 
ATOM   2264 H HD23 . LEU A 1 175 ? 3.317   -13.47  15.21   1     20.839 ? 343 LEU A HD23 1 c 
ATOM   2265 N N    . ALA A 1 176 ? -0.61   -8.669  16.876  1     17.991 ? 344 ALA A N    1 ? 
ATOM   2266 C CA   . ALA A 1 176 ? -0.926  -7.316  17.325  1     19.234 ? 344 ALA A CA   1 ? 
ATOM   2267 C C    . ALA A 1 176 ? -0.871  -7.201  18.854  1     19.149 ? 344 ALA A C    1 ? 
ATOM   2268 O O    . ALA A 1 176 ? -0.282  -6.277  19.398  1     17.381 ? 344 ALA A O    1 ? 
ATOM   2269 C CB   . ALA A 1 176 ? -2.281  -6.895  16.773  1     17.508 ? 344 ALA A CB   1 ? 
ATOM   2270 H H    . ALA A 1 176 ? -1.22   -9.121  16.367  1     18.53  ? 344 ALA A H    1 c 
ATOM   2271 H HA   . ALA A 1 176 ? -0.231  -6.705  16.952  1     18.638 ? 344 ALA A HA   1 c 
ATOM   2272 H HB1  . ALA A 1 176 ? -2.345  -7.142  15.835  1     18.022 ? 344 ALA A HB1  1 c 
ATOM   2273 H HB2  . ALA A 1 176 ? -2.989  -7.336  17.271  1     18.079 ? 344 ALA A HB2  1 c 
ATOM   2274 H HB3  . ALA A 1 176 ? -2.383  -5.932  16.858  1     18.019 ? 344 ALA A HB3  1 c 
ATOM   2275 N N    . ARG A 1 177 ? -1.511  -8.138  19.582  1     18.064 ? 345 ARG A N    1 ? 
ATOM   2276 C CA   . ARG A 1 177 ? -1.488  -8.087  21.048  1     20.305 ? 345 ARG A CA   1 ? 
ATOM   2277 C C    . ARG A 1 177 ? -0.046  -8.209  21.557  1     17.187 ? 345 ARG A C    1 ? 
ATOM   2278 O O    . ARG A 1 177 ? 0.363   -7.516  22.466  1     15.679 ? 345 ARG A O    1 ? 
ATOM   2279 C CB   . ARG A 1 177 ? -2.373  -9.192  21.635  1     21.642 ? 345 ARG A CB   1 ? 
ATOM   2280 C CG   . ARG A 1 177 ? -3.851  -8.972  21.319  1     29.711 ? 345 ARG A CG   1 ? 
ATOM   2281 C CD   . ARG A 1 177 ? -4.777  -9.932  22.102  1     35.256 ? 345 ARG A CD   1 ? 
ATOM   2282 N NE   . ARG A 1 177 ? -4.317  -11.325 21.984  1     41.879 ? 345 ARG A NE   1 ? 
ATOM   2283 C CZ   . ARG A 1 177 ? -4.763  -12.269 21.142  1     43.631 ? 345 ARG A CZ   1 ? 
ATOM   2284 N NH1  . ARG A 1 177 ? -5.696  -11.973 20.243  1     40.005 ? 345 ARG A NH1  1 ? 
ATOM   2285 N NH2  . ARG A 1 177 ? -4.257  -13.498 21.217  1     39.991 ? 345 ARG A NH2  1 ? 
ATOM   2286 H H    . ARG A 1 177 ? -1.964  -8.813  19.164  1     18.923 ? 345 ARG A H    1 c 
ATOM   2287 H HA   . ARG A 1 177 ? -1.85   -7.209  21.333  1     19.469 ? 345 ARG A HA   1 c 
ATOM   2288 H HB2  . ARG A 1 177 ? -2.09   -10.057 21.27   1     23.006 ? 345 ARG A HB2  1 c 
ATOM   2289 H HB3  . ARG A 1 177 ? -2.253  -9.219  22.609  1     22.917 ? 345 ARG A HB3  1 c 
ATOM   2290 H HG2  . ARG A 1 177 ? -4.094  -8.045  21.534  1     28.688 ? 345 ARG A HG2  1 c 
ATOM   2291 H HG3  . ARG A 1 177 ? -3.994  -9.109  20.363  1     28.593 ? 345 ARG A HG3  1 c 
ATOM   2292 H HD2  . ARG A 1 177 ? -4.785  -9.675  23.047  1     35.361 ? 345 ARG A HD2  1 c 
ATOM   2293 H HD3  . ARG A 1 177 ? -5.691  -9.858  21.76   1     35.38  ? 345 ARG A HD3  1 c 
ATOM   2294 H HE   . ARG A 1 177 ? -3.68   -11.567 22.527  1     40.478 ? 345 ARG A HE   1 c 
ATOM   2295 H HH11 . ARG A 1 177 ? -5.564  -11.309 19.675  1     41.054 ? 345 ARG A HH11 1 c 
ATOM   2296 H HH12 . ARG A 1 177 ? -6.445  -12.443 20.217  1     41.08  ? 345 ARG A HH12 1 c 
ATOM   2297 H HH21 . ARG A 1 177 ? -3.806  -13.753 21.933  1     41.02  ? 345 ARG A HH21 1 c 
ATOM   2298 H HH22 . ARG A 1 177 ? -4.381  -14.062 20.547  1     40.827 ? 345 ARG A HH22 1 c 
ATOM   2299 N N    . LYS A 1 178 ? 0.766   -9.022  20.906  1     16.398 ? 346 LYS A N    1 ? 
ATOM   2300 C CA   . LYS A 1 178 ? 2.167   -9.168  21.294  1     17.145 ? 346 LYS A CA   1 ? 
ATOM   2301 C C    . LYS A 1 178 ? 2.985   -7.898  21.115  1     17.369 ? 346 LYS A C    1 ? 
ATOM   2302 O O    . LYS A 1 178 ? 3.884   -7.605  21.902  1     20.342 ? 346 LYS A O    1 ? 
ATOM   2303 C CB   . LYS A 1 178 ? 2.786   -10.346 20.557  1     16.467 ? 346 LYS A CB   1 ? 
ATOM   2304 C CG   . LYS A 1 178 ? 2.373   -11.721 21.074  1     18.037 ? 346 LYS A CG   1 ? 
ATOM   2305 C CD   . LYS A 1 178 ? 2.827   -12.847 20.146  1     18.51  ? 346 LYS A CD   1 ? 
ATOM   2306 C CE   . LYS A 1 178 ? 3.043   -14.18  20.859  1     20.027 ? 346 LYS A CE   1 ? 
ATOM   2307 N NZ   . LYS A 1 178 ? 1.805   -14.691 21.428  1     20.13  ? 346 LYS A NZ   1 ? 
ATOM   2308 H H    . LYS A 1 178 ? 0.447   -9.519  20.208  1     16.779 ? 346 LYS A H    1 c 
ATOM   2309 H HA   . LYS A 1 178 ? 2.185   -9.399  22.258  1     16.905 ? 346 LYS A HA   1 c 
ATOM   2310 H HB2  . LYS A 1 178 ? 2.545   -10.287 19.608  1     16.969 ? 346 LYS A HB2  1 c 
ATOM   2311 H HB3  . LYS A 1 178 ? 3.761   -10.274 20.619  1     16.98  ? 346 LYS A HB3  1 c 
ATOM   2312 H HG2  . LYS A 1 178 ? 2.766   -11.855 21.964  1     17.784 ? 346 LYS A HG2  1 c 
ATOM   2313 H HG3  . LYS A 1 178 ? 1.396   -11.747 21.163  1     17.781 ? 346 LYS A HG3  1 c 
ATOM   2314 H HD2  . LYS A 1 178 ? 2.153   -12.968 19.443  1     18.732 ? 346 LYS A HD2  1 c 
ATOM   2315 H HD3  . LYS A 1 178 ? 3.667   -12.581 19.711  1     18.721 ? 346 LYS A HD3  1 c 
ATOM   2316 H HE2  . LYS A 1 178 ? 3.389   -14.831 20.223  1     19.717 ? 346 LYS A HE2  1 c 
ATOM   2317 H HE3  . LYS A 1 178 ? 3.703   -14.07  21.564  1     19.786 ? 346 LYS A HE3  1 c 
ATOM   2318 H HZ1  . LYS A 1 178 ? 1.288   -15.029 20.767  1     20.103 ? 346 LYS A HZ1  1 c 
ATOM   2319 H HZ2  . LYS A 1 178 ? 1.349   -14.042 21.863  1     20.079 ? 346 LYS A HZ2  1 c 
ATOM   2320 H HZ3  . LYS A 1 178 ? 1.997   -15.354 22.014  1     20.095 ? 346 LYS A HZ3  1 c 
ATOM   2321 N N    . MET A 1 179 ? 2.686   -7.136  20.053  1     16.467 ? 347 MET A N    1 ? 
ATOM   2322 C CA   . MET A 1 179 ? 3.429   -5.918  19.818  1     15.076 ? 347 MET A CA   1 ? 
ATOM   2323 C C    . MET A 1 179 ? 3       -4.864  20.842  1     15.18  ? 347 MET A C    1 ? 
ATOM   2324 O O    . MET A 1 179 ? 3.827   -4.135  21.346  1     15.23  ? 347 MET A O    1 ? 
ATOM   2325 C CB   . MET A 1 179 ? 3.174   -5.428  18.395  1     16.22  ? 347 MET A CB   1 ? 
ATOM   2326 C CG   . MET A 1 179 ? 3.893   -4.125  18.061  1     16.368 ? 347 MET A CG   1 ? 
ATOM   2327 S SD   . MET A 1 179 ? 5.676   -4.166  18.314  1     17.709 ? 347 MET A SD   1 ? 
ATOM   2328 C CE   . MET A 1 179 ? 6.237   -5.256  17.009  1     16.612 ? 347 MET A CE   1 ? 
ATOM   2329 H H    . MET A 1 179 ? 2.025   -7.381  19.471  1     16.354 ? 347 MET A H    1 c 
ATOM   2330 H HA   . MET A 1 179 ? 4.393   -6.109  19.936  1     15.605 ? 347 MET A HA   1 c 
ATOM   2331 H HB2  . MET A 1 179 ? 3.462   -6.124  17.766  1     15.991 ? 347 MET A HB2  1 c 
ATOM   2332 H HB3  . MET A 1 179 ? 2.209   -5.299  18.276  1     15.986 ? 347 MET A HB3  1 c 
ATOM   2333 H HG2  . MET A 1 179 ? 3.723   -3.904  17.123  1     16.579 ? 347 MET A HG2  1 c 
ATOM   2334 H HG3  . MET A 1 179 ? 3.52    -3.403  18.603  1     16.573 ? 347 MET A HG3  1 c 
ATOM   2335 H HE1  . MET A 1 179 ? 7.124   -5.596  17.23   1     16.882 ? 347 MET A HE1  1 c 
ATOM   2336 H HE2  . MET A 1 179 ? 5.615   -5.999  16.916  1     16.876 ? 347 MET A HE2  1 c 
ATOM   2337 H HE3  . MET A 1 179 ? 6.28    -4.761  16.17   1     16.88  ? 347 MET A HE3  1 c 
ATOM   2338 N N    . VAL A 1 180 ? 1.703   -4.796  21.139  1     15.009 ? 348 VAL A N    1 ? 
ATOM   2339 C CA   . VAL A 1 180 ? 1.255   -3.895  22.197  1     13.711 ? 348 VAL A CA   1 ? 
ATOM   2340 C C    . VAL A 1 180 ? 1.852   -4.303  23.547  1     14.76  ? 348 VAL A C    1 ? 
ATOM   2341 O O    . VAL A 1 180 ? 2.227   -3.409  24.317  1     15.292 ? 348 VAL A O    1 ? 
ATOM   2342 C CB   . VAL A 1 180 ? -0.275  -3.818  22.227  1     14.772 ? 348 VAL A CB   1 ? 
ATOM   2343 C CG1  . VAL A 1 180 ? -0.756  -3.045  23.472  1     14.643 ? 348 VAL A CG1  1 ? 
ATOM   2344 C CG2  . VAL A 1 180 ? -0.799  -3.2    20.92   1     16.181 ? 348 VAL A CG2  1 ? 
ATOM   2345 H H    . VAL A 1 180 ? 1.092   -5.303  20.686  1     14.777 ? 348 VAL A H    1 c 
ATOM   2346 H HA   . VAL A 1 180 ? 1.588   -3.001  21.984  1     14.363 ? 348 VAL A HA   1 c 
ATOM   2347 H HB   . VAL A 1 180 ? -0.615  -4.741  22.289  1     14.79  ? 348 VAL A HB   1 c 
ATOM   2348 H HG11 . VAL A 1 180 ? -0.16   -2.296  23.643  1     14.687 ? 348 VAL A HG11 1 c 
ATOM   2349 H HG12 . VAL A 1 180 ? -0.761  -3.637  24.243  1     14.706 ? 348 VAL A HG12 1 c 
ATOM   2350 H HG13 . VAL A 1 180 ? -1.656  -2.71   23.318  1     14.701 ? 348 VAL A HG13 1 c 
ATOM   2351 H HG21 . VAL A 1 180 ? -1.76   -3.065  20.987  1     15.745 ? 348 VAL A HG21 1 c 
ATOM   2352 H HG22 . VAL A 1 180 ? -0.61   -3.794  20.177  1     15.749 ? 348 VAL A HG22 1 c 
ATOM   2353 H HG23 . VAL A 1 180 ? -0.363  -2.345  20.769  1     15.741 ? 348 VAL A HG23 1 c 
ATOM   2354 N N    . ALA A 1 181 ? 1.929   -5.603  23.826  1     15.398 ? 349 ALA A N    1 ? 
ATOM   2355 C CA   . ALA A 1 181 ? 2.547   -6.082  25.068  1     17.456 ? 349 ALA A CA   1 ? 
ATOM   2356 C C    . ALA A 1 181 ? 4.016   -5.643  25.16   1     17.01  ? 349 ALA A C    1 ? 
ATOM   2357 O O    . ALA A 1 181 ? 4.507   -5.256  26.239  1     15.456 ? 349 ALA A O    1 ? 
ATOM   2358 C CB   . ALA A 1 181 ? 2.369   -7.584  25.161  1     20.11  ? 349 ALA A CB   1 ? 
ATOM   2359 H H    . ALA A 1 181 ? 1.582   -6.214  23.241  1     15.685 ? 349 ALA A H    1 c 
ATOM   2360 H HA   . ALA A 1 181 ? 2.059   -5.661  25.829  1     17.394 ? 349 ALA A HA   1 c 
ATOM   2361 H HB1  . ALA A 1 181 ? 1.422   -7.801  25.159  1     19.285 ? 349 ALA A HB1  1 c 
ATOM   2362 H HB2  . ALA A 1 181 ? 2.799   -8.011  24.401  1     19.285 ? 349 ALA A HB2  1 c 
ATOM   2363 H HB3  . ALA A 1 181 ? 2.772   -7.911  25.983  1     19.285 ? 349 ALA A HB3  1 c 
ATOM   2364 N N    . LEU A 1 182 ? 4.715   -5.665  24.031  1     15.221 ? 350 LEU A N    1 ? 
ATOM   2365 C CA   . LEU A 1 182 ? 6.113   -5.224  24.026  1     16.073 ? 350 LEU A CA   1 ? 
ATOM   2366 C C    . LEU A 1 182 ? 6.221   -3.732  24.32   1     17.677 ? 350 LEU A C    1 ? 
ATOM   2367 O O    . LEU A 1 182 ? 7.066   -3.317  25.129  1     15.972 ? 350 LEU A O    1 ? 
ATOM   2368 C CB   . LEU A 1 182 ? 6.788   -5.578  22.717  1     15.565 ? 350 LEU A CB   1 ? 
ATOM   2369 C CG   . LEU A 1 182 ? 8.235   -5.092  22.56   1     16.446 ? 350 LEU A CG   1 ? 
ATOM   2370 C CD1  . LEU A 1 182 ? 9.148   -5.659  23.683  1     17.786 ? 350 LEU A CD1  1 ? 
ATOM   2371 C CD2  . LEU A 1 182 ? 8.701   -5.565  21.206  1     16.978 ? 350 LEU A CD2  1 ? 
ATOM   2372 H H    . LEU A 1 182 ? 4.338   -5.967  23.255  1     15.827 ? 350 LEU A H    1 c 
ATOM   2373 H HA   . LEU A 1 182 ? 6.579   -5.703  24.755  1     16.12  ? 350 LEU A HA   1 c 
ATOM   2374 H HB2  . LEU A 1 182 ? 6.776   -6.558  22.623  1     15.89  ? 350 LEU A HB2  1 c 
ATOM   2375 H HB3  . LEU A 1 182 ? 6.251   -5.2    21.983  1     15.885 ? 350 LEU A HB3  1 c 
ATOM   2376 H HG   . LEU A 1 182 ? 8.255   -4.101  22.582  1     16.616 ? 350 LEU A HG   1 c 
ATOM   2377 H HD11 . LEU A 1 182 ? 8.959   -5.199  24.519  1     17.381 ? 350 LEU A HD11 1 c 
ATOM   2378 H HD12 . LEU A 1 182 ? 10.08   -5.524  23.444  1     17.386 ? 350 LEU A HD12 1 c 
ATOM   2379 H HD13 . LEU A 1 182 ? 8.977   -6.61   23.792  1     17.386 ? 350 LEU A HD13 1 c 
ATOM   2380 H HD21 . LEU A 1 182 ? 8.173   -5.135  20.513  1     16.815 ? 350 LEU A HD21 1 c 
ATOM   2381 H HD22 . LEU A 1 182 ? 8.594   -6.528  21.143  1     16.807 ? 350 LEU A HD22 1 c 
ATOM   2382 H HD23 . LEU A 1 182 ? 9.638   -5.336  21.087  1     16.815 ? 350 LEU A HD23 1 c 
ATOM   2383 N N    . ILE A 1 183 ? 5.356   -2.92   23.673  1     16.179 ? 351 ILE A N    1 ? 
ATOM   2384 C CA   . ILE A 1 183 ? 5.341   -1.5    23.967  1     17.291 ? 351 ILE A CA   1 ? 
ATOM   2385 C C    . ILE A 1 183 ? 5.023   -1.24   25.451  1     18.576 ? 351 ILE A C    1 ? 
ATOM   2386 O O    . ILE A 1 183 ? 5.638   -0.389  26.104  1     16.679 ? 351 ILE A O    1 ? 
ATOM   2387 C CB   . ILE A 1 183 ? 4.374   -0.79   22.979  1     16.676 ? 351 ILE A CB   1 ? 
ATOM   2388 C CG1  . ILE A 1 183 ? 4.852   -0.916  21.53   1     16.712 ? 351 ILE A CG1  1 ? 
ATOM   2389 C CG2  . ILE A 1 183 ? 4.155   0.657   23.391  1     16.972 ? 351 ILE A CG2  1 ? 
ATOM   2390 C CD1  . ILE A 1 183 ? 3.761   -0.539  20.511  1     17.641 ? 351 ILE A CD1  1 ? 
ATOM   2391 H H    . ILE A 1 183 ? 4.77    -3.263  23.062  1     16.759 ? 351 ILE A H    1 c 
ATOM   2392 H HA   . ILE A 1 183 ? 6.239   -1.156  23.793  1     17.178 ? 351 ILE A HA   1 c 
ATOM   2393 H HB   . ILE A 1 183 ? 3.511   -1.245  23.041  1     16.852 ? 351 ILE A HB   1 c 
ATOM   2394 H HG12 . ILE A 1 183 ? 5.624   -0.329  21.399  1     16.906 ? 351 ILE A HG12 1 c 
ATOM   2395 H HG13 . ILE A 1 183 ? 5.14    -1.835  21.36   1     16.895 ? 351 ILE A HG13 1 c 
ATOM   2396 H HG21 . ILE A 1 183 ? 3.842   1.173   22.629  1     16.895 ? 351 ILE A HG21 1 c 
ATOM   2397 H HG22 . ILE A 1 183 ? 4.991   1.036   23.711  1     16.898 ? 351 ILE A HG22 1 c 
ATOM   2398 H HG23 . ILE A 1 183 ? 3.49    0.698   24.098  1     16.896 ? 351 ILE A HG23 1 c 
ATOM   2399 H HD11 . ILE A 1 183 ? 2.891   -0.846  20.828  1     17.361 ? 351 ILE A HD11 1 c 
ATOM   2400 H HD12 . ILE A 1 183 ? 3.959   -0.96   19.654  1     17.363 ? 351 ILE A HD12 1 c 
ATOM   2401 H HD13 . ILE A 1 183 ? 3.74    0.43    20.397  1     17.361 ? 351 ILE A HD13 1 c 
ATOM   2402 N N    . ALA A 1 184 ? 4.082   -1.993  26.024  1     17.405 ? 352 ALA A N    1 ? 
ATOM   2403 C CA   . ALA A 1 184 ? 3.751   -1.815  27.434  1     17.668 ? 352 ALA A CA   1 ? 
ATOM   2404 C C    . ALA A 1 184 ? 4.933   -2.244  28.325  1     15.823 ? 352 ALA A C    1 ? 
ATOM   2405 O O    . ALA A 1 184 ? 5.216   -1.637  29.359  1     15.104 ? 352 ALA A O    1 ? 
ATOM   2406 C CB   . ALA A 1 184 ? 2.5     -2.588  27.73   1     16.797 ? 352 ALA A CB   1 ? 
ATOM   2407 H H    . ALA A 1 184 ? 3.632   -2.62   25.534  1     17.717 ? 352 ALA A H    1 c 
ATOM   2408 H HA   . ALA A 1 184 ? 3.58    -0.851  27.597  1     17.096 ? 352 ALA A HA   1 c 
ATOM   2409 H HB1  . ALA A 1 184 ? 1.77    -2.251  27.184  1     17.053 ? 352 ALA A HB1  1 c 
ATOM   2410 H HB2  . ALA A 1 184 ? 2.642   -3.529  27.532  1     17.053 ? 352 ALA A HB2  1 c 
ATOM   2411 H HB3  . ALA A 1 184 ? 2.27    -2.49   28.67   1     17.053 ? 352 ALA A HB3  1 c 
ATOM   2412 N N    . ARG A 1 185 ? 5.664   -3.258  27.891  1     15.822 ? 353 ARG A N    1 ? 
ATOM   2413 C CA   . ARG A 1 185 ? 6.81    -3.739  28.657  1     16.911 ? 353 ARG A CA   1 ? 
ATOM   2414 C C    . ARG A 1 185 ? 7.912   -2.673  28.654  1     17.353 ? 353 ARG A C    1 ? 
ATOM   2415 O O    . ARG A 1 185 ? 8.581   -2.388  29.671  1     17.437 ? 353 ARG A O    1 ? 
ATOM   2416 C CB   . ARG A 1 185 ? 7.291   -5.093  28.132  1     16.622 ? 353 ARG A CB   1 ? 
ATOM   2417 C CG   . ARG A 1 185 ? 8.39    -5.666  29.047  1     16.589 ? 353 ARG A CG   1 ? 
ATOM   2418 C CD   . ARG A 1 185 ? 8.938   -6.928  28.526  1     16.847 ? 353 ARG A CD   1 ? 
ATOM   2419 N NE   . ARG A 1 185 ? 9.913   -7.54   29.432  1     17.78  ? 353 ARG A NE   1 ? 
ATOM   2420 C CZ   . ARG A 1 185 ? 10.355  -8.753  29.369  1     19.117 ? 353 ARG A CZ   1 ? 
ATOM   2421 N NH1  . ARG A 1 185 ? 10.079  -9.498  28.301  1     19.244 ? 353 ARG A NH1  1 ? 
ATOM   2422 N NH2  . ARG A 1 185 ? 11.07   -9.225  30.386  1     21.339 ? 353 ARG A NH2  1 ? 
ATOM   2423 H H    . ARG A 1 185 ? 5.443   -3.683  27.113  1     16.092 ? 353 ARG A H    1 c 
ATOM   2424 H HA   . ARG A 1 185 ? 6.517   -3.874  29.594  1     16.705 ? 353 ARG A HA   1 c 
ATOM   2425 H HB2  . ARG A 1 185 ? 6.536   -5.719  28.098  1     16.68  ? 353 ARG A HB2  1 c 
ATOM   2426 H HB3  . ARG A 1 185 ? 7.646   -4.987  27.224  1     16.68  ? 353 ARG A HB3  1 c 
ATOM   2427 H HG2  . ARG A 1 185 ? 9.12    -5.016  29.133  1     16.661 ? 353 ARG A HG2  1 c 
ATOM   2428 H HG3  . ARG A 1 185 ? 8.017   -5.825  29.942  1     16.658 ? 353 ARG A HG3  1 c 
ATOM   2429 H HD2  . ARG A 1 185 ? 8.2     -7.554  28.378  1     17.01  ? 353 ARG A HD2  1 c 
ATOM   2430 H HD3  . ARG A 1 185 ? 9.363   -6.76   27.662  1     17.002 ? 353 ARG A HD3  1 c 
ATOM   2431 H HE   . ARG A 1 185 ? 10.228  -7.041  30.074  1     17.897 ? 353 ARG A HE   1 c 
ATOM   2432 H HH11 . ARG A 1 185 ? 10.302  -9.213  27.495  1     19.195 ? 353 ARG A HH11 1 c 
ATOM   2433 H HH12 . ARG A 1 185 ? 9.673   -10.276 28.403  1     19.203 ? 353 ARG A HH12 1 c 
ATOM   2434 H HH21 . ARG A 1 185 ? 10.814  -9.062  31.216  1     20.605 ? 353 ARG A HH21 1 c 
ATOM   2435 H HH22 . ARG A 1 185 ? 11.798  -9.701  30.227  1     20.623 ? 353 ARG A HH22 1 c 
ATOM   2436 N N    . ILE A 1 186 ? 8.072   -2.03   27.491  1     15.735 ? 354 ILE A N    1 ? 
ATOM   2437 C CA   . ILE A 1 186 ? 9.058   -0.981  27.353  1     15.788 ? 354 ILE A CA   1 ? 
ATOM   2438 C C    . ILE A 1 186 ? 8.682   0.142   28.308  1     14.316 ? 354 ILE A C    1 ? 
ATOM   2439 O O    . ILE A 1 186 ? 9.524   0.705   28.991  1     14.071 ? 354 ILE A O    1 ? 
ATOM   2440 C CB   . ILE A 1 186 ? 9.099   -0.497  25.894  1     15.679 ? 354 ILE A CB   1 ? 
ATOM   2441 C CG1  . ILE A 1 186 ? 9.765   -1.547  24.946  1     15.936 ? 354 ILE A CG1  1 ? 
ATOM   2442 C CG2  . ILE A 1 186 ? 9.795   0.851   25.821  1     17.176 ? 354 ILE A CG2  1 ? 
ATOM   2443 C CD1  . ILE A 1 186 ? 9.557   -1.284  23.458  1     15.848 ? 354 ILE A CD1  1 ? 
ATOM   2444 H H    . ILE A 1 186 ? 7.571   -2.267  26.764  1     16.118 ? 354 ILE A H    1 c 
ATOM   2445 H HA   . ILE A 1 186 ? 9.936   -1.333  27.597  1     15.509 ? 354 ILE A HA   1 c 
ATOM   2446 H HB   . ILE A 1 186 ? 8.178   -0.372  25.595  1     16.024 ? 354 ILE A HB   1 c 
ATOM   2447 H HG12 . ILE A 1 186 ? 10.727  -1.56   25.126  1     15.87  ? 354 ILE A HG12 1 c 
ATOM   2448 H HG13 . ILE A 1 186 ? 9.413   -2.434  25.161  1     15.861 ? 354 ILE A HG13 1 c 
ATOM   2449 H HG21 . ILE A 1 186 ? 10.107  1.009   24.915  1     16.697 ? 354 ILE A HG21 1 c 
ATOM   2450 H HG22 . ILE A 1 186 ? 10.557  0.862   26.426  1     16.695 ? 354 ILE A HG22 1 c 
ATOM   2451 H HG23 . ILE A 1 186 ? 9.174   1.557   26.07   1     16.698 ? 354 ILE A HG23 1 c 
ATOM   2452 H HD11 . ILE A 1 186 ? 8.631   -1.016  23.3    1     15.875 ? 354 ILE A HD11 1 c 
ATOM   2453 H HD12 . ILE A 1 186 ? 9.748   -2.097  22.953  1     15.875 ? 354 ILE A HD12 1 c 
ATOM   2454 H HD13 . ILE A 1 186 ? 10.155  -0.572  23.162  1     15.88  ? 354 ILE A HD13 1 c 
ATOM   2455 N N    . ASN A 1 187 ? 7.434   0.58    28.23   1     14.49  ? 355 ASN A N    1 ? 
ATOM   2456 C CA   . ASN A 1 187 ? 6.972   1.681   29.055  1     14.757 ? 355 ASN A CA   1 ? 
ATOM   2457 C C    . ASN A 1 187 ? 7.161   1.418   30.543  1     14.49  ? 355 ASN A C    1 ? 
ATOM   2458 O O    . ASN A 1 187 ? 7.617   2.304   31.273  1     15.318 ? 355 ASN A O    1 ? 
ATOM   2459 C CB   . ASN A 1 187 ? 5.529   2.019   28.733  1     16.408 ? 355 ASN A CB   1 ? 
ATOM   2460 C CG   . ASN A 1 187 ? 5.077   3.236   29.516  1     17.821 ? 355 ASN A CG   1 ? 
ATOM   2461 O OD1  . ASN A 1 187 ? 5.531   4.356   29.283  1     18.504 ? 355 ASN A OD1  1 ? 
ATOM   2462 N ND2  . ASN A 1 187 ? 4.152   3.054   30.426  1     18.085 ? 355 ASN A ND2  1 ? 
ATOM   2463 H H    . ASN A 1 187 ? 6.852   0.194   27.641  1     14.536 ? 355 ASN A H    1 c 
ATOM   2464 H HA   . ASN A 1 187 ? 7.511   2.469   28.825  1     14.963 ? 355 ASN A HA   1 c 
ATOM   2465 H HB2  . ASN A 1 187 ? 5.446   2.197   27.776  1     16.349 ? 355 ASN A HB2  1 c 
ATOM   2466 H HB3  . ASN A 1 187 ? 4.958   1.257   28.954  1     16.354 ? 355 ASN A HB3  1 c 
ATOM   2467 H HD21 . ASN A 1 187 ? 3.502   3.65    30.521  1     18     ? 355 ASN A HD21 1 c 
ATOM   2468 H HD22 . ASN A 1 187 ? 4.177   2.336   30.946  1     17.99  ? 355 ASN A HD22 1 c 
ATOM   2469 N N    . THR A 1 188 ? 6.763   0.247   31.031  1     15.042 ? 356 THR A N    1 ? 
ATOM   2470 C CA   . THR A 1 188 ? 6.871   -0.012  32.469  1     15.396 ? 356 THR A CA   1 ? 
ATOM   2471 C C    . THR A 1 188 ? 8.35    -0.015  32.9    1     15.978 ? 356 THR A C    1 ? 
ATOM   2472 O O    . THR A 1 188 ? 8.72    0.589   33.916  1     15.191 ? 356 THR A O    1 ? 
ATOM   2473 C CB   . THR A 1 188 ? 6.171   -1.316  32.76   1     18.859 ? 356 THR A CB   1 ? 
ATOM   2474 O OG1  . THR A 1 188 ? 4.773   -1.032  32.705  1     21.498 ? 356 THR A OG1  1 ? 
ATOM   2475 C CG2  . THR A 1 188 ? 6.519   -1.843  34.124  1     18.469 ? 356 THR A CG2  1 ? 
ATOM   2476 H H    . THR A 1 188 ? 6.418   -0.394  30.477  1     15.032 ? 356 THR A H    1 c 
ATOM   2477 H HA   . THR A 1 188 ? 6.404   0.706   32.95   1     16.044 ? 356 THR A HA   1 c 
ATOM   2478 H HB   . THR A 1 188 ? 6.4     -1.992  32.079  1     18.524 ? 356 THR A HB   1 c 
ATOM   2479 H HG21 . THR A 1 188 ? 5.827   -2.459  34.418  1     18.59  ? 356 THR A HG21 1 c 
ATOM   2480 H HG22 . THR A 1 188 ? 6.582   -1.106  34.755  1     18.551 ? 356 THR A HG22 1 c 
ATOM   2481 H HG23 . THR A 1 188 ? 7.365   -2.309  34.084  1     18.567 ? 356 THR A HG23 1 c 
ATOM   2482 N N    . TYR A 1 189 ? 9.192   -0.632  32.069  1     14.459 ? 357 TYR A N    1 ? 
ATOM   2483 C CA   . TYR A 1 189 ? 10.631  -0.675  32.355  1     14.701 ? 357 TYR A CA   1 ? 
ATOM   2484 C C    . TYR A 1 189 ? 11.215  0.717   32.402  1     13.974 ? 357 TYR A C    1 ? 
ATOM   2485 O O    . TYR A 1 189 ? 12      1.065   33.3    1     16.221 ? 357 TYR A O    1 ? 
ATOM   2486 C CB   . TYR A 1 189 ? 11.337  -1.55   31.317  1     14.75  ? 357 TYR A CB   1 ? 
ATOM   2487 C CG   . TYR A 1 189 ? 12.835  -1.624  31.552  1     15.372 ? 357 TYR A CG   1 ? 
ATOM   2488 C CD1  . TYR A 1 189 ? 13.683  -0.697  30.963  1     15.355 ? 357 TYR A CD1  1 ? 
ATOM   2489 C CD2  . TYR A 1 189 ? 13.402  -2.64   32.305  1     14.994 ? 357 TYR A CD2  1 ? 
ATOM   2490 C CE1  . TYR A 1 189 ? 15.061  -0.741  31.183  1     18.122 ? 357 TYR A CE1  1 ? 
ATOM   2491 C CE2  . TYR A 1 189 ? 14.762  -2.673  32.557  1     16.824 ? 357 TYR A CE2  1 ? 
ATOM   2492 C CZ   . TYR A 1 189 ? 15.594  -1.724  31.993  1     17.456 ? 357 TYR A CZ   1 ? 
ATOM   2493 O OH   . TYR A 1 189 ? 16.948  -1.808  32.235  1     17.414 ? 357 TYR A OH   1 ? 
ATOM   2494 H H    . TYR A 1 189 ? 8.876   -1.048  31.318  1     14.868 ? 357 TYR A H    1 c 
ATOM   2495 H HA   . TYR A 1 189 ? 10.754  -1.093  33.248  1     14.526 ? 357 TYR A HA   1 c 
ATOM   2496 H HB2  . TYR A 1 189 ? 10.959  -2.457  31.356  1     14.878 ? 357 TYR A HB2  1 c 
ATOM   2497 H HB3  . TYR A 1 189 ? 11.169  -1.18   30.422  1     14.878 ? 357 TYR A HB3  1 c 
ATOM   2498 H HD1  . TYR A 1 189 ? 13.32   -0.004  30.436  1     15.969 ? 357 TYR A HD1  1 c 
ATOM   2499 H HD2  . TYR A 1 189 ? 12.841  -3.27   32.727  1     15.518 ? 357 TYR A HD2  1 c 
ATOM   2500 H HE1  . TYR A 1 189 ? 15.62   -0.088  30.802  1     17.264 ? 357 TYR A HE1  1 c 
ATOM   2501 H HE2  . TYR A 1 189 ? 15.126  -3.356  33.093  1     16.514 ? 357 TYR A HE2  1 c 
ATOM   2502 N N    . ALA A 1 190 ? 10.894  1.547   31.384  1     15.413 ? 358 ALA A N    1 ? 
ATOM   2503 C CA   . ALA A 1 190 ? 11.523  2.836   31.279  1     14.207 ? 358 ALA A CA   1 ? 
ATOM   2504 C C    . ALA A 1 190 ? 11.037  3.781   32.366  1     14.723 ? 358 ALA A C    1 ? 
ATOM   2505 O O    . ALA A 1 190 ? 11.88   4.462   32.996  1     16.241 ? 358 ALA A O    1 ? 
ATOM   2506 C CB   . ALA A 1 190 ? 11.248  3.454   29.921  1     15.315 ? 358 ALA A CB   1 ? 
ATOM   2507 H H    . ALA A 1 190 ? 10.281  1.294   30.754  1     14.783 ? 358 ALA A H    1 c 
ATOM   2508 H HA   . ALA A 1 190 ? 12.507  2.716   31.386  1     14.742 ? 358 ALA A HA   1 c 
ATOM   2509 H HB1  . ALA A 1 190 ? 11.478  2.82    29.221  1     14.978 ? 358 ALA A HB1  1 c 
ATOM   2510 H HB2  . ALA A 1 190 ? 10.306  3.684   29.849  1     14.977 ? 358 ALA A HB2  1 c 
ATOM   2511 H HB3  . ALA A 1 190 ? 11.783  4.256   29.816  1     14.978 ? 358 ALA A HB3  1 c 
ATOM   2512 N N    . LYS A 1 191 ? 9.704   3.798   32.589  1     13.184 ? 359 LYS A N    1 ? 
ATOM   2513 C CA   . LYS A 1 191 ? 9.158   4.704   33.607  1     13.901 ? 359 LYS A CA   1 ? 
ATOM   2514 C C    . LYS A 1 191 ? 9.705   4.37    34.991  1     12.82  ? 359 LYS A C    1 ? 
ATOM   2515 O O    . LYS A 1 191 ? 9.844   5.244   35.864  1     13.721 ? 359 LYS A O    1 ? 
ATOM   2516 C CB   . LYS A 1 191 ? 7.62    4.601   33.565  1     14.062 ? 359 LYS A CB   1 ? 
ATOM   2517 C CG   . LYS A 1 191 ? 6.914   5.24    32.398  1     15.365 ? 359 LYS A CG   1 ? 
ATOM   2518 C CD   . LYS A 1 191 ? 7.008   6.72    32.319  1     17.594 ? 359 LYS A CD   1 ? 
ATOM   2519 C CE   . LYS A 1 191 ? 6.102   7.364   31.295  1     17.318 ? 359 LYS A CE   1 ? 
ATOM   2520 N NZ   . LYS A 1 191 ? 6.268   6.85    29.938  1     17.009 ? 359 LYS A NZ   1 ? 
ATOM   2521 H H    . LYS A 1 191 ? 9.14    3.263   32.107  1     13.718 ? 359 LYS A H    1 c 
ATOM   2522 H HA   . LYS A 1 191 ? 9.422   5.624   33.375  1     13.625 ? 359 LYS A HA   1 c 
ATOM   2523 H HB2  . LYS A 1 191 ? 7.376   3.651   33.583  1     14.317 ? 359 LYS A HB2  1 c 
ATOM   2524 H HB3  . LYS A 1 191 ? 7.267   5.006   34.386  1     14.31  ? 359 LYS A HB3  1 c 
ATOM   2525 H HG2  . LYS A 1 191 ? 7.283   4.862   31.571  1     15.538 ? 359 LYS A HG2  1 c 
ATOM   2526 H HG3  . LYS A 1 191 ? 5.966   4.988   32.437  1     15.539 ? 359 LYS A HG3  1 c 
ATOM   2527 H HD2  . LYS A 1 191 ? 6.798   7.093   33.203  1     16.979 ? 359 LYS A HD2  1 c 
ATOM   2528 H HD3  . LYS A 1 191 ? 7.937   6.963   32.112  1     16.959 ? 359 LYS A HD3  1 c 
ATOM   2529 H HE2  . LYS A 1 191 ? 5.176   7.23    31.566  1     17.314 ? 359 LYS A HE2  1 c 
ATOM   2530 H HE3  . LYS A 1 191 ? 6.27    8.323   31.285  1     17.349 ? 359 LYS A HE3  1 c 
ATOM   2531 H HZ1  . LYS A 1 191 ? 5.68    6.176   29.792  1     17.104 ? 359 LYS A HZ1  1 c 
ATOM   2532 H HZ2  . LYS A 1 191 ? 7.112   6.539   29.821  1     17.099 ? 359 LYS A HZ2  1 c 
ATOM   2533 H HZ3  . LYS A 1 191 ? 6.115   7.512   29.341  1     17.107 ? 359 LYS A HZ3  1 c 
ATOM   2534 N N    . ALA A 1 192 ? 9.993   3.104   35.247  1     15.512 ? 360 ALA A N    1 ? 
ATOM   2535 C CA   . ALA A 1 192 ? 10.54   2.721   36.542  1     15.892 ? 360 ALA A CA   1 ? 
ATOM   2536 C C    . ALA A 1 192 ? 11.923  3.345   36.789  1     16.052 ? 360 ALA A C    1 ? 
ATOM   2537 O O    . ALA A 1 192 ? 12.281  3.674   37.923  1     16.918 ? 360 ALA A O    1 ? 
ATOM   2538 C CB   . ALA A 1 192 ? 10.599  1.229   36.628  1     17.374 ? 360 ALA A CB   1 ? 
ATOM   2539 H H    . ALA A 1 192 ? 9.829   2.456   34.623  1     14.91  ? 360 ALA A H    1 c 
ATOM   2540 H HA   . ALA A 1 192 ? 9.925   3.057   37.248  1     16.079 ? 360 ALA A HA   1 c 
ATOM   2541 H HB1  . ALA A 1 192 ? 9.697   0.865   36.623  1     16.915 ? 360 ALA A HB1  1 c 
ATOM   2542 H HB2  . ALA A 1 192 ? 11.09   0.876   35.868  1     16.913 ? 360 ALA A HB2  1 c 
ATOM   2543 H HB3  . ALA A 1 192 ? 11.046  0.965   37.45   1     16.911 ? 360 ALA A HB3  1 c 
ATOM   2544 N N    . ARG A 1 193 ? 12.664  3.557   35.707  1     17.286 ? 361 ARG A N    1 ? 
ATOM   2545 C CA   . ARG A 1 193 ? 13.991  4.155   35.744  1     17.831 ? 361 ARG A CA   1 ? 
ATOM   2546 C C    . ARG A 1 193 ? 13.952  5.668   35.619  1     17.353 ? 361 ARG A C    1 ? 
ATOM   2547 O O    . ARG A 1 193 ? 14.849  6.322   36.134  1     16.333 ? 361 ARG A O    1 ? 
ATOM   2548 C CB   . ARG A 1 193 ? 14.855  3.505   34.675  1     17.955 ? 361 ARG A CB   1 ? 
ATOM   2549 C CG   . ARG A 1 193 ? 15.218  2.119   35.212  1     20.071 ? 361 ARG A CG   1 ? 
ATOM   2550 C CD   . ARG A 1 193 ? 15.432  1.122   34.088  1     19.392 ? 361 ARG A CD   1 ? 
ATOM   2551 N NE   . ARG A 1 193 ? 15.767  -0.174  34.697  1     19.706 ? 361 ARG A NE   1 ? 
ATOM   2552 C CZ   . ARG A 1 193 ? 14.877  -0.993  35.272  1     19.949 ? 361 ARG A CZ   1 ? 
ATOM   2553 N NH1  . ARG A 1 193 ? 13.574  -0.742  35.217  1     18.417 ? 361 ARG A NH1  1 ? 
ATOM   2554 N NH2  . ARG A 1 193 ? 15.299  -2.087  35.849  1     19.58  ? 361 ARG A NH2  1 ? 
ATOM   2555 H H    . ARG A 1 193 ? 12.338  3.295   34.895  1     17.06  ? 361 ARG A H    1 c 
ATOM   2556 H HA   . ARG A 1 193 ? 14.398  3.944   36.616  1     17.661 ? 361 ARG A HA   1 c 
ATOM   2557 H HB2  . ARG A 1 193 ? 14.362  3.424   33.83   1     18.377 ? 361 ARG A HB2  1 c 
ATOM   2558 H HB3  . ARG A 1 193 ? 15.669  4.031   34.522  1     18.376 ? 361 ARG A HB3  1 c 
ATOM   2559 H HG2  . ARG A 1 193 ? 16.042  2.184   35.743  1     19.412 ? 361 ARG A HG2  1 c 
ATOM   2560 H HG3  . ARG A 1 193 ? 14.504  1.791   35.8    1     19.384 ? 361 ARG A HG3  1 c 
ATOM   2561 H HD2  . ARG A 1 193 ? 14.623  1.034   33.544  1     19.589 ? 361 ARG A HD2  1 c 
ATOM   2562 H HD3  . ARG A 1 193 ? 16.167  1.414   33.511  1     19.611 ? 361 ARG A HD3  1 c 
ATOM   2563 H HE   . ARG A 1 193 ? 16.601  -0.426  34.682  1     19.69  ? 361 ARG A HE   1 c 
ATOM   2564 H HH11 . ARG A 1 193 ? 13.222  -0.133  35.751  1     18.857 ? 361 ARG A HH11 1 c 
ATOM   2565 H HH12 . ARG A 1 193 ? 13.062  -1.19   34.654  1     18.847 ? 361 ARG A HH12 1 c 
ATOM   2566 H HH21 . ARG A 1 193 ? 15.918  -2.58   35.455  1     19.693 ? 361 ARG A HH21 1 c 
ATOM   2567 H HH22 . ARG A 1 193 ? 14.963  -2.329  36.629  1     19.693 ? 361 ARG A HH22 1 c 
ATOM   2568 N N    . ASN A 1 194 ? 12.976  6.2     34.879  1     16.763 ? 362 ASN A N    1 ? 
ATOM   2569 C CA   . ASN A 1 194 ? 12.789  7.636   34.78   1     16.377 ? 362 ASN A CA   1 ? 
ATOM   2570 C C    . ASN A 1 194 ? 11.316  7.914   34.55   1     15.434 ? 362 ASN A C    1 ? 
ATOM   2571 O O    . ASN A 1 194 ? 10.8    7.62    33.487  1     14.738 ? 362 ASN A O    1 ? 
ATOM   2572 C CB   . ASN A 1 194 ? 13.591  8.208   33.625  1     16.995 ? 362 ASN A CB   1 ? 
ATOM   2573 C CG   . ASN A 1 194 ? 13.417  9.683   33.435  1     16.785 ? 362 ASN A CG   1 ? 
ATOM   2574 O OD1  . ASN A 1 194 ? 12.665  10.344  34.16   1     17.111 ? 362 ASN A OD1  1 ? 
ATOM   2575 N ND2  . ASN A 1 194 ? 14.133  10.248  32.471  1     15.041 ? 362 ASN A ND2  1 ? 
ATOM   2576 H H    . ASN A 1 194 ? 12.42   5.652   34.404  1     16.813 ? 362 ASN A H    1 c 
ATOM   2577 H HA   . ASN A 1 194 ? 13.094  8.064   35.608  1     16.388 ? 362 ASN A HA   1 c 
ATOM   2578 H HB2  . ASN A 1 194 ? 14.538  8.022   33.779  1     16.8   ? 362 ASN A HB2  1 c 
ATOM   2579 H HB3  . ASN A 1 194 ? 13.332  7.749   32.803  1     16.787 ? 362 ASN A HB3  1 c 
ATOM   2580 H HD21 . ASN A 1 194 ? 14.1    11.126  32.353  1     15.572 ? 362 ASN A HD21 1 c 
ATOM   2581 H HD22 . ASN A 1 194 ? 14.644  9.749   31.944  1     15.57  ? 362 ASN A HD22 1 c 
ATOM   2582 N N    . PRO A 1 195 ? 10.555  8.446   35.533  1     15.862 ? 363 PRO A N    1 ? 
ATOM   2583 C CA   . PRO A 1 195 ? 9.115   8.554   35.366  1     15.725 ? 363 PRO A CA   1 ? 
ATOM   2584 C C    . PRO A 1 195 ? 8.744   9.606   34.324  1     15.511 ? 363 PRO A C    1 ? 
ATOM   2585 O O    . PRO A 1 195 ? 7.604   9.655   33.888  1     17.307 ? 363 PRO A O    1 ? 
ATOM   2586 C CB   . PRO A 1 195 ? 8.598   8.901   36.756  1     16.232 ? 363 PRO A CB   1 ? 
ATOM   2587 C CG   . PRO A 1 195 ? 9.802   9.55    37.409  1     16.327 ? 363 PRO A CG   1 ? 
ATOM   2588 C CD   . PRO A 1 195 ? 11.01   8.818   36.869  1     16.043 ? 363 PRO A CD   1 ? 
ATOM   2589 H HA   . PRO A 1 195 ? 8.755   7.673   35.094  1     15.796 ? 363 PRO A HA   1 c 
ATOM   2590 H HB2  . PRO A 1 195 ? 7.84    9.528   36.71   1     16.136 ? 363 PRO A HB2  1 c 
ATOM   2591 H HB3  . PRO A 1 195 ? 8.324   8.092   37.245  1     16.138 ? 363 PRO A HB3  1 c 
ATOM   2592 H HG2  . PRO A 1 195 ? 9.847   10.502  37.18   1     16.241 ? 363 PRO A HG2  1 c 
ATOM   2593 H HG3  . PRO A 1 195 ? 9.755   9.465   38.384  1     16.241 ? 363 PRO A HG3  1 c 
ATOM   2594 H HD2  . PRO A 1 195 ? 11.794  9.409   36.831  1     16.068 ? 363 PRO A HD2  1 c 
ATOM   2595 H HD3  . PRO A 1 195 ? 11.219  8.025   37.412  1     16.064 ? 363 PRO A HD3  1 c 
ATOM   2596 N N    . ASP A 1 196 ? 9.715   10.43   33.917  1     15.3   ? 364 ASP A N    1 ? 
ATOM   2597 C CA   . ASP A 1 196 ? 9.519   11.419  32.857  1     16.529 ? 364 ASP A CA   1 ? 
ATOM   2598 C C    . ASP A 1 196 ? 9.775   10.877  31.449  1     19.436 ? 364 ASP A C    1 ? 
ATOM   2599 O O    . ASP A 1 196 ? 9.604   11.633  30.484  1     17.513 ? 364 ASP A O    1 ? 
ATOM   2600 C CB   . ASP A 1 196 ? 10.35   12.656  33.141  1     19.361 ? 364 ASP A CB   1 ? 
ATOM   2601 C CG   . ASP A 1 196 ? 9.856   13.404  34.372  1     25.301 ? 364 ASP A CG   1 ? 
ATOM   2602 O OD1  . ASP A 1 196 ? 8.605   13.573  34.496  1     26.713 ? 364 ASP A OD1  1 ? 
ATOM   2603 O OD2  . ASP A 1 196 ? 10.695  13.836  35.199  1     34.928 ? 364 ASP A OD2  1 ? 
ATOM   2604 H H    . ASP A 1 196 ? 10.524  10.414  34.34   1     15.672 ? 364 ASP A H    1 c 
ATOM   2605 H HA   . ASP A 1 196 ? 8.584   11.713  32.889  1     17.401 ? 364 ASP A HA   1 c 
ATOM   2606 H HB2  . ASP A 1 196 ? 11.286  12.402  33.279  1     19.884 ? 364 ASP A HB2  1 c 
ATOM   2607 H HB3  . ASP A 1 196 ? 10.309  13.268  32.376  1     19.859 ? 364 ASP A HB3  1 c 
ATOM   2608 N N    . PHE A 1 197 ? 10.261  9.65    31.334  1     19.089 ? 365 PHE A N    1 ? 
ATOM   2609 C CA   . PHE A 1 197 ? 10.745  9.148   30.045  1     17.711 ? 365 PHE A CA   1 ? 
ATOM   2610 C C    . PHE A 1 197 ? 9.545   8.764   29.179  1     17.313 ? 365 PHE A C    1 ? 
ATOM   2611 O O    . PHE A 1 197 ? 8.765   7.875   29.527  1     18.711 ? 365 PHE A O    1 ? 
ATOM   2612 C CB   . PHE A 1 197 ? 11.642  7.949   30.293  1     16.086 ? 365 PHE A CB   1 ? 
ATOM   2613 C CG   . PHE A 1 197 ? 12.407  7.437   29.082  1     14.984 ? 365 PHE A CG   1 ? 
ATOM   2614 C CD1  . PHE A 1 197 ? 11.837  6.481   28.251  1     15.127 ? 365 PHE A CD1  1 ? 
ATOM   2615 C CD2  . PHE A 1 197 ? 13.66   7.942   28.761  1     14.217 ? 365 PHE A CD2  1 ? 
ATOM   2616 C CE1  . PHE A 1 197 ? 12.518  5.976   27.154  1     14.631 ? 365 PHE A CE1  1 ? 
ATOM   2617 C CE2  . PHE A 1 197 ? 14.353  7.431   27.665  1     15.835 ? 365 PHE A CE2  1 ? 
ATOM   2618 C CZ   . PHE A 1 197 ? 13.781  6.451   26.878  1     15.619 ? 365 PHE A CZ   1 ? 
ATOM   2619 H H    . PHE A 1 197 ? 10.295  9.098   32.06   1     18.747 ? 365 PHE A H    1 c 
ATOM   2620 H HA   . PHE A 1 197 ? 11.271  9.856   29.597  1     17.571 ? 365 PHE A HA   1 c 
ATOM   2621 H HB2  . PHE A 1 197 ? 12.29   8.194   30.987  1     16.19  ? 365 PHE A HB2  1 c 
ATOM   2622 H HB3  . PHE A 1 197 ? 11.092  7.217   30.651  1     16.2   ? 365 PHE A HB3  1 c 
ATOM   2623 H HD1  . PHE A 1 197 ? 10.985  6.135   28.465  1     14.987 ? 365 PHE A HD1  1 c 
ATOM   2624 H HD2  . PHE A 1 197 ? 14.064  8.588   29.318  1     14.783 ? 365 PHE A HD2  1 c 
ATOM   2625 H HE1  . PHE A 1 197 ? 12.127  5.312   26.613  1     14.993 ? 365 PHE A HE1  1 c 
ATOM   2626 H HE2  . PHE A 1 197 ? 15.212  7.762   27.456  1     15.387 ? 365 PHE A HE2  1 c 
ATOM   2627 H HZ   . PHE A 1 197 ? 14.242  6.136   26.117  1     15.419 ? 365 PHE A HZ   1 c 
ATOM   2628 N N    . LYS A 1 198 ? 9.393   9.451   28.049  1     15.811 ? 366 LYS A N    1 ? 
ATOM   2629 C CA   . LYS A 1 198 ? 8.235   9.289   27.192  1     15.415 ? 366 LYS A CA   1 ? 
ATOM   2630 C C    . LYS A 1 198 ? 8.401   8.134   26.215  1     16.048 ? 366 LYS A C    1 ? 
ATOM   2631 O O    . LYS A 1 198 ? 9.486   7.788   25.819  1     16.587 ? 366 LYS A O    1 ? 
ATOM   2632 C CB   . LYS A 1 198 ? 8.062   10.617  26.439  1     16.244 ? 366 LYS A CB   1 ? 
ATOM   2633 C CG   . LYS A 1 198 ? 7.847   11.82   27.342  1     18.068 ? 366 LYS A CG   1 ? 
ATOM   2634 C CD   . LYS A 1 198 ? 6.612   11.664  28.239  1     17.408 ? 366 LYS A CD   1 ? 
ATOM   2635 C CE   . LYS A 1 198 ? 6.269   12.891  29.012  1     20.883 ? 366 LYS A CE   1 ? 
ATOM   2636 N NZ   . LYS A 1 198 ? 7.371   13.291  29.884  1     20.793 ? 366 LYS A NZ   1 ? 
ATOM   2637 H H    . LYS A 1 198 ? 10.046  10.036  27.794  1     16.111 ? 366 LYS A H    1 c 
ATOM   2638 H HA   . LYS A 1 198 ? 7.447   9.122   27.758  1     15.784 ? 366 LYS A HA   1 c 
ATOM   2639 H HB2  . LYS A 1 198 ? 8.859   10.777  25.89   1     16.448 ? 366 LYS A HB2  1 c 
ATOM   2640 H HB3  . LYS A 1 198 ? 7.293   10.54   25.835  1     16.45  ? 366 LYS A HB3  1 c 
ATOM   2641 H HG2  . LYS A 1 198 ? 8.643   11.945  27.903  1     17.483 ? 366 LYS A HG2  1 c 
ATOM   2642 H HG3  . LYS A 1 198 ? 7.741   12.618  26.785  1     17.489 ? 366 LYS A HG3  1 c 
ATOM   2643 H HD2  . LYS A 1 198 ? 5.845   11.42   27.677  1     18.3   ? 366 LYS A HD2  1 c 
ATOM   2644 H HD3  . LYS A 1 198 ? 6.765   10.93   28.871  1     18.297 ? 366 LYS A HD3  1 c 
ATOM   2645 H HE2  . LYS A 1 198 ? 6.074   13.619  28.4    1     19.998 ? 366 LYS A HE2  1 c 
ATOM   2646 H HE3  . LYS A 1 198 ? 5.477   12.726  29.554  1     20.006 ? 366 LYS A HE3  1 c 
ATOM   2647 H HZ1  . LYS A 1 198 ? 8.001   13.732  29.406  1     20.795 ? 366 LYS A HZ1  1 c 
ATOM   2648 H HZ2  . LYS A 1 198 ? 7.744   12.564  30.273  1     20.77  ? 366 LYS A HZ2  1 c 
ATOM   2649 H HZ3  . LYS A 1 198 ? 7.057   13.841  30.532  1     20.806 ? 366 LYS A HZ3  1 c 
ATOM   2650 N N    . VAL A 1 199 ? 7.279   7.531   25.86   1     13.902 ? 367 VAL A N    1 ? 
ATOM   2651 C CA   . VAL A 1 199 ? 7.197   6.418   24.936  1     14.189 ? 367 VAL A CA   1 ? 
ATOM   2652 C C    . VAL A 1 199 ? 6.288   6.794   23.771  1     17.602 ? 367 VAL A C    1 ? 
ATOM   2653 O O    . VAL A 1 199 ? 5.094   7.055   23.968  1     15.042 ? 367 VAL A O    1 ? 
ATOM   2654 C CB   . VAL A 1 199 ? 6.682   5.151   25.642  1     14.919 ? 367 VAL A CB   1 ? 
ATOM   2655 C CG1  . VAL A 1 199 ? 6.387   3.978   24.687  1     16.036 ? 367 VAL A CG1  1 ? 
ATOM   2656 C CG2  . VAL A 1 199 ? 7.657   4.718   26.72   1     15.55  ? 367 VAL A CG2  1 ? 
ATOM   2657 H H    . VAL A 1 199 ? 6.497   7.839   26.218  1     14.486 ? 367 VAL A H    1 c 
ATOM   2658 H HA   . VAL A 1 199 ? 8.088   6.233   24.591  1     14.884 ? 367 VAL A HA   1 c 
ATOM   2659 H HB   . VAL A 1 199 ? 5.835   5.393   26.087  1     15.096 ? 367 VAL A HB   1 c 
ATOM   2660 H HG11 . VAL A 1 199 ? 7.057   3.956   23.983  1     15.703 ? 367 VAL A HG11 1 c 
ATOM   2661 H HG12 . VAL A 1 199 ? 5.507   4.094   24.291  1     15.71  ? 367 VAL A HG12 1 c 
ATOM   2662 H HG13 . VAL A 1 199 ? 6.409   3.139   25.179  1     15.701 ? 367 VAL A HG13 1 c 
ATOM   2663 H HG21 . VAL A 1 199 ? 7.376   3.865   27.088  1     15.365 ? 367 VAL A HG21 1 c 
ATOM   2664 H HG22 . VAL A 1 199 ? 7.675   5.383   27.429  1     15.356 ? 367 VAL A HG22 1 c 
ATOM   2665 H HG23 . VAL A 1 199 ? 8.545   4.629   26.339  1     15.372 ? 367 VAL A HG23 1 c 
ATOM   2666 N N    . VAL A 1 200 ? 6.882   6.753   22.572  1     15.38  ? 368 VAL A N    1 ? 
ATOM   2667 C CA   . VAL A 1 200 ? 6.244   7.199   21.336  1     15.693 ? 368 VAL A CA   1 ? 
ATOM   2668 C C    . VAL A 1 200 ? 6.469   6.155   20.251  1     15.5   ? 368 VAL A C    1 ? 
ATOM   2669 O O    . VAL A 1 200 ? 7.5     6.129   19.601  1     14.589 ? 368 VAL A O    1 ? 
ATOM   2670 C CB   . VAL A 1 200 ? 6.788   8.56    20.915  1     14.95  ? 368 VAL A CB   1 ? 
ATOM   2671 C CG1  . VAL A 1 200 ? 6.087   9.052   19.642  1     16.528 ? 368 VAL A CG1  1 ? 
ATOM   2672 C CG2  . VAL A 1 200 ? 6.675   9.604   22.052  1     16.631 ? 368 VAL A CG2  1 ? 
ATOM   2673 H H    . VAL A 1 200 ? 7.733   6.426   22.516  1     15.929 ? 368 VAL A H    1 c 
ATOM   2674 H HA   . VAL A 1 200 ? 5.292   7.291   21.494  1     15.458 ? 368 VAL A HA   1 c 
ATOM   2675 H HB   . VAL A 1 200 ? 7.745   8.443   20.711  1     15.667 ? 368 VAL A HB   1 c 
ATOM   2676 H HG11 . VAL A 1 200 ? 5.164   8.753   19.641  1     16.031 ? 368 VAL A HG11 1 c 
ATOM   2677 H HG12 . VAL A 1 200 ? 6.541   8.693   18.862  1     16.043 ? 368 VAL A HG12 1 c 
ATOM   2678 H HG13 . VAL A 1 200 ? 6.111   10.023  19.609  1     16.049 ? 368 VAL A HG13 1 c 
ATOM   2679 H HG21 . VAL A 1 200 ? 6.884   10.487  21.705  1     16.131 ? 368 VAL A HG21 1 c 
ATOM   2680 H HG22 . VAL A 1 200 ? 7.299   9.382   22.762  1     16.122 ? 368 VAL A HG22 1 c 
ATOM   2681 H HG23 . VAL A 1 200 ? 5.769   9.602   22.405  1     16.125 ? 368 VAL A HG23 1 c 
ATOM   2682 N N    . PRO A 1 201 ? 5.508   5.262   19.999  1     14.173 ? 369 PRO A N    1 ? 
ATOM   2683 C CA   . PRO A 1 201 ? 5.575   4.364   18.835  1     13.57  ? 369 PRO A CA   1 ? 
ATOM   2684 C C    . PRO A 1 201 ? 5.454   5.172   17.549  1     14.847 ? 369 PRO A C    1 ? 
ATOM   2685 O O    . PRO A 1 201 ? 4.814   6.209   17.564  1     15.984 ? 369 PRO A O    1 ? 
ATOM   2686 C CB   . PRO A 1 201 ? 4.384   3.425   18.972  1     15.356 ? 369 PRO A CB   1 ? 
ATOM   2687 C CG   . PRO A 1 201 ? 3.574   3.964   20.137  1     16.789 ? 369 PRO A CG   1 ? 
ATOM   2688 C CD   . PRO A 1 201 ? 4.302   5.044   20.817  1     15.188 ? 369 PRO A CD   1 ? 
ATOM   2689 H HA   . PRO A 1 201 ? 6.416   3.852   18.846  1     14.255 ? 369 PRO A HA   1 c 
ATOM   2690 H HB2  . PRO A 1 201 ? 3.844   3.416   18.147  1     15.237 ? 369 PRO A HB2  1 c 
ATOM   2691 H HB3  . PRO A 1 201 ? 4.686   2.504   19.155  1     15.238 ? 369 PRO A HB3  1 c 
ATOM   2692 H HG2  . PRO A 1 201 ? 2.714   4.303   19.813  1     16.069 ? 369 PRO A HG2  1 c 
ATOM   2693 H HG3  . PRO A 1 201 ? 3.389   3.241   20.772  1     16.066 ? 369 PRO A HG3  1 c 
ATOM   2694 H HD2  . PRO A 1 201 ? 3.754   5.85    20.854  1     15.303 ? 369 PRO A HD2  1 c 
ATOM   2695 H HD3  . PRO A 1 201 ? 4.542   4.781   21.733  1     15.299 ? 369 PRO A HD3  1 c 
ATOM   2696 N N    . GLN A 1 202 ? 5.985   4.613   16.457  1     17.564 ? 370 GLN A N    1 ? 
ATOM   2697 C CA   . GLN A 1 202 ? 5.813   5.236   15.148  1     14.853 ? 370 GLN A CA   1 ? 
ATOM   2698 C C    . GLN A 1 202 ? 4.935   4.323   14.297  1     15.714 ? 370 GLN A C    1 ? 
ATOM   2699 O O    . GLN A 1 202 ? 5.201   3.131   14.198  1     18.86  ? 370 GLN A O    1 ? 
ATOM   2700 C CB   . GLN A 1 202 ? 7.143   5.424   14.418  1     18.637 ? 370 GLN A CB   1 ? 
ATOM   2701 C CG   . GLN A 1 202 ? 6.929   6.111   13.07   1     18.194 ? 370 GLN A CG   1 ? 
ATOM   2702 C CD   . GLN A 1 202 ? 8.19    6.487   12.336  1     17.483 ? 370 GLN A CD   1 ? 
ATOM   2703 O OE1  . GLN A 1 202 ? 8.426   7.674   12.09   1     17.93  ? 370 GLN A OE1  1 ? 
ATOM   2704 N NE2  . GLN A 1 202 ? 8.93    5.486   11.873  1     20.125 ? 370 GLN A NE2  1 ? 
ATOM   2705 H H    . GLN A 1 202 ? 6.459   3.835   16.522  1     16.214 ? 370 GLN A H    1 c 
ATOM   2706 H HA   . GLN A 1 202 ? 5.377   6.113   15.259  1     16.151 ? 370 GLN A HA   1 c 
ATOM   2707 H HB2  . GLN A 1 202 ? 7.744   5.967   14.97   1     17.595 ? 370 GLN A HB2  1 c 
ATOM   2708 H HB3  . GLN A 1 202 ? 7.564   4.55    14.276  1     17.592 ? 370 GLN A HB3  1 c 
ATOM   2709 H HG2  . GLN A 1 202 ? 6.416   5.518   12.49   1     18.104 ? 370 GLN A HG2  1 c 
ATOM   2710 H HG3  . GLN A 1 202 ? 6.395   6.923   13.207  1     18.12  ? 370 GLN A HG3  1 c 
ATOM   2711 H HE21 . GLN A 1 202 ? 9.814   5.557   11.864  1     19.27  ? 370 GLN A HE21 1 c 
ATOM   2712 H HE22 . GLN A 1 202 ? 8.539   4.748   11.573  1     19.264 ? 370 GLN A HE22 1 c 
ATOM   2713 N N    . ASN A 1 203 ? 3.934   4.929   13.653  1     15.411 ? 371 ASN A N    1 ? 
ATOM   2714 C CA   . ASN A 1 203 ? 3.013   4.237   12.786  1     16.966 ? 371 ASN A CA   1 ? 
ATOM   2715 C C    . ASN A 1 203 ? 2.18    3.207   13.546  1     17.57  ? 371 ASN A C    1 ? 
ATOM   2716 O O    . ASN A 1 203 ? 2.112   3.237   14.771  1     19.172 ? 371 ASN A O    1 ? 
ATOM   2717 C CB   . ASN A 1 203 ? 3.754   3.724   11.565  1     16.069 ? 371 ASN A CB   1 ? 
ATOM   2718 C CG   . ASN A 1 203 ? 4.353   4.885   10.81   1     17.485 ? 371 ASN A CG   1 ? 
ATOM   2719 O OD1  . ASN A 1 203 ? 3.739   5.954   10.756  1     15.621 ? 371 ASN A OD1  1 ? 
ATOM   2720 N ND2  . ASN A 1 203 ? 5.525   4.681   10.236  1     17.944 ? 371 ASN A ND2  1 ? 
ATOM   2721 H H    . ASN A 1 203 ? 3.824   5.83    13.762  1     15.823 ? 371 ASN A H    1 c 
ATOM   2722 H HA   . ASN A 1 203 ? 2.375   4.907   12.461  1     16.608 ? 371 ASN A HA   1 c 
ATOM   2723 H HB2  . ASN A 1 203 ? 4.461   3.106   11.834  1     16.617 ? 371 ASN A HB2  1 c 
ATOM   2724 H HB3  . ASN A 1 203 ? 3.139   3.249   10.977  1     16.632 ? 371 ASN A HB3  1 c 
ATOM   2725 H HD21 . ASN A 1 203 ? 6.088   5.357   10.128  1     17.799 ? 371 ASN A HD21 1 c 
ATOM   2726 H HD22 . ASN A 1 203 ? 5.747   3.868   9.957   1     17.78  ? 371 ASN A HD22 1 c 
ATOM   2727 N N    . SER A 1 204 ? 1.501   2.31    12.778  1     16.748 ? 372 SER A N    1 ? 
ATOM   2728 C CA   . SER A 1 204 ? 0.625   1.302   13.35   1     16.451 ? 372 SER A CA   1 ? 
ATOM   2729 C C    . SER A 1 204 ? -0.388  1.882   14.34   1     16.042 ? 372 SER A C    1 ? 
ATOM   2730 O O    . SER A 1 204 ? -0.64   1.298   15.413  1     16.322 ? 372 SER A O    1 ? 
ATOM   2731 C CB   . SER A 1 204 ? 1.418   0.209   13.996  1     17.013 ? 372 SER A CB   1 ? 
ATOM   2732 O OG   . SER A 1 204 ? 2.227   -0.479  13.027  1     16.745 ? 372 SER A OG   1 ? 
ATOM   2733 H H    . SER A 1 204 ? 1.568   2.352   11.869  1     16.864 ? 372 SER A H    1 c 
ATOM   2734 H HA   . SER A 1 204 ? 0.112   0.902   12.606  1     16.548 ? 372 SER A HA   1 c 
ATOM   2735 H HB2  . SER A 1 204 ? 1.991   0.586   14.69   1     16.833 ? 372 SER A HB2  1 c 
ATOM   2736 H HB3  . SER A 1 204 ? 0.811   -0.431  14.415  1     16.815 ? 372 SER A HB3  1 c 
ATOM   2737 N N    . PRO A 1 205 ? -1.066  2.989   14.049  1     16.985 ? 373 PRO A N    1 ? 
ATOM   2738 C CA   . PRO A 1 205 ? -1.997  3.593   15.026  1     16.701 ? 373 PRO A CA   1 ? 
ATOM   2739 C C    . PRO A 1 205 ? -3.196  2.726   15.381  1     17.16  ? 373 PRO A C    1 ? 
ATOM   2740 O O    . PRO A 1 205 ? -3.892  2.975   16.369  1     18.073 ? 373 PRO A O    1 ? 
ATOM   2741 C CB   . PRO A 1 205 ? -2.408  4.875   14.298  1     16.986 ? 373 PRO A CB   1 ? 
ATOM   2742 C CG   . PRO A 1 205 ? -2.331  4.492   12.861  1     17.984 ? 373 PRO A CG   1 ? 
ATOM   2743 C CD   . PRO A 1 205 ? -1.005  3.762   12.794  1     17.845 ? 373 PRO A CD   1 ? 
ATOM   2744 H HA   . PRO A 1 205 ? -1.496  3.825   15.848  1     16.887 ? 373 PRO A HA   1 c 
ATOM   2745 H HB2  . PRO A 1 205 ? -3.319  5.15    14.545  1     17.15  ? 373 PRO A HB2  1 c 
ATOM   2746 H HB3  . PRO A 1 205 ? -1.784  5.611   14.5    1     17.155 ? 373 PRO A HB3  1 c 
ATOM   2747 H HG2  . PRO A 1 205 ? -3.072  3.903   12.611  1     17.735 ? 373 PRO A HG2  1 c 
ATOM   2748 H HG3  . PRO A 1 205 ? -2.334  5.281   12.281  1     17.779 ? 373 PRO A HG3  1 c 
ATOM   2749 H HD2  . PRO A 1 205 ? -0.96   3.175   12.007  1     17.665 ? 373 PRO A HD2  1 c 
ATOM   2750 H HD3  . PRO A 1 205 ? -0.251  4.385   12.79   1     17.68  ? 373 PRO A HD3  1 c 
ATOM   2751 N N    . GLU A 1 206 ? -3.485  1.733   14.508  1     17.338 ? 374 GLU A N    1 ? 
ATOM   2752 C CA   . GLU A 1 206 ? -4.643  0.892   14.704  1     15.628 ? 374 GLU A CA   1 ? 
ATOM   2753 C C    . GLU A 1 206 ? -4.481  0.021   15.943  1     14.838 ? 374 GLU A C    1 ? 
ATOM   2754 O O    . GLU A 1 206 ? -5.475  -0.518  16.454  1     16.228 ? 374 GLU A O    1 ? 
ATOM   2755 C CB   . GLU A 1 206 ? -4.885  0.012   13.48   1     13.958 ? 374 GLU A CB   1 ? 
ATOM   2756 C CG   . GLU A 1 206 ? -3.733  -0.934  13.171  1     16.835 ? 374 GLU A CG   1 ? 
ATOM   2757 C CD   . GLU A 1 206 ? -2.561  -0.408  12.32   1     18.295 ? 374 GLU A CD   1 ? 
ATOM   2758 O OE1  . GLU A 1 206 ? -2.543  0.788   11.98   1     19.027 ? 374 GLU A OE1  1 ? 
ATOM   2759 O OE2  . GLU A 1 206 ? -1.657  -1.225  11.973  1     19.982 ? 374 GLU A OE2  1 ? 
ATOM   2760 H H    . GLU A 1 206 ? -2.986  1.63    13.752  1     16.874 ? 374 GLU A H    1 c 
ATOM   2761 H HA   . GLU A 1 206 ? -5.434  1.476   14.83   1     15.495 ? 374 GLU A HA   1 c 
ATOM   2762 H HB2  . GLU A 1 206 ? -5.693  -0.52   13.633  1     14.956 ? 374 GLU A HB2  1 c 
ATOM   2763 H HB3  . GLU A 1 206 ? -5.05   0.587   12.705  1     14.982 ? 374 GLU A HB3  1 c 
ATOM   2764 H HG2  . GLU A 1 206 ? -3.362  -1.263  14.015  1     16.425 ? 374 GLU A HG2  1 c 
ATOM   2765 H HG3  . GLU A 1 206 ? -4.102  -1.719  12.711  1     16.43  ? 374 GLU A HG3  1 c 
ATOM   2766 N N    . LEU A 1 207 ? -3.268  -0.035  16.495  1     15.874 ? 375 LEU A N    1 ? 
ATOM   2767 C CA   . LEU A 1 207 ? -3.012  -0.768  17.737  1     15.225 ? 375 LEU A CA   1 ? 
ATOM   2768 C C    . LEU A 1 207 ? -3.689  -0.095  18.928  1     15.986 ? 375 LEU A C    1 ? 
ATOM   2769 O O    . LEU A 1 207 ? -3.892  -0.727  19.96   1     16.564 ? 375 LEU A O    1 ? 
ATOM   2770 C CB   . LEU A 1 207 ? -1.513  -0.942  18.001  1     15.231 ? 375 LEU A CB   1 ? 
ATOM   2771 C CG   . LEU A 1 207 ? -0.758  -1.808  16.982  1     15.917 ? 375 LEU A CG   1 ? 
ATOM   2772 C CD1  . LEU A 1 207 ? 0.694   -1.934  17.349  1     16.872 ? 375 LEU A CD1  1 ? 
ATOM   2773 C CD2  . LEU A 1 207 ? -1.334  -3.156  16.76   1     17.893 ? 375 LEU A CD2  1 ? 
ATOM   2774 H H    . LEU A 1 207 ? -2.557  0.346   16.068  1     15.499 ? 375 LEU A H    1 c 
ATOM   2775 H HA   . LEU A 1 207 ? -3.419  -1.665  17.641  1     15.511 ? 375 LEU A HA   1 c 
ATOM   2776 H HB2  . LEU A 1 207 ? -1.098  -0.049  18.019  1     15.384 ? 375 LEU A HB2  1 c 
ATOM   2777 H HB3  . LEU A 1 207 ? -1.402  -1.343  18.893  1     15.391 ? 375 LEU A HB3  1 c 
ATOM   2778 H HG   . LEU A 1 207 ? -0.794  -1.335  16.111  1     16.328 ? 375 LEU A HG   1 c 
ATOM   2779 H HD11 . LEU A 1 207 ? 1.052   -1.057  17.564  1     16.582 ? 375 LEU A HD11 1 c 
ATOM   2780 H HD12 . LEU A 1 207 ? 1.188   -2.309  16.6    1     16.586 ? 375 LEU A HD12 1 c 
ATOM   2781 H HD13 . LEU A 1 207 ? 0.785   -2.518  18.12   1     16.582 ? 375 LEU A HD13 1 c 
ATOM   2782 H HD21 . LEU A 1 207 ? -2.154  -3.077  16.243  1     17.247 ? 375 LEU A HD21 1 c 
ATOM   2783 H HD22 . LEU A 1 207 ? -1.531  -3.57   17.616  1     17.264 ? 375 LEU A HD22 1 c 
ATOM   2784 H HD23 . LEU A 1 207 ? -0.699  -3.707  16.272  1     17.259 ? 375 LEU A HD23 1 c 
ATOM   2785 N N    . VAL A 1 208 ? -4.124  1.128   18.723  1     17.148 ? 376 VAL A N    1 ? 
ATOM   2786 C CA   . VAL A 1 208 ? -4.922  1.864   19.682  1     17.467 ? 376 VAL A CA   1 ? 
ATOM   2787 C C    . VAL A 1 208 ? -6.18   1.084   20.091  1     18.317 ? 376 VAL A C    1 ? 
ATOM   2788 O O    . VAL A 1 208 ? -6.745  1.41    21.11   1     18.542 ? 376 VAL A O    1 ? 
ATOM   2789 C CB   . VAL A 1 208 ? -5.287  3.252   19.148  1     17.819 ? 376 VAL A CB   1 ? 
ATOM   2790 C CG1  . VAL A 1 208 ? -6.336  3.14    18.049  1     19.283 ? 376 VAL A CG1  1 ? 
ATOM   2791 C CG2  . VAL A 1 208 ? -5.768  4.183   20.284  1     16.514 ? 376 VAL A CG2  1 ? 
ATOM   2792 H H    . VAL A 1 208 ? -3.87   1.564   17.963  1     16.914 ? 376 VAL A H    1 c 
ATOM   2793 H HA   . VAL A 1 208 ? -4.384  1.983   20.479  1     17.569 ? 376 VAL A HA   1 c 
ATOM   2794 H HB   . VAL A 1 208 ? -4.47   3.645   18.764  1     17.76  ? 376 VAL A HB   1 c 
ATOM   2795 H HG11 . VAL A 1 208 ? -7.221  3.126   18.445  1     18.795 ? 376 VAL A HG11 1 c 
ATOM   2796 H HG12 . VAL A 1 208 ? -6.196  2.323   17.54   1     18.807 ? 376 VAL A HG12 1 c 
ATOM   2797 H HG13 . VAL A 1 208 ? -6.263  3.905   17.453  1     18.824 ? 376 VAL A HG13 1 c 
ATOM   2798 H HG21 . VAL A 1 208 ? -5.749  5.105   19.976  1     16.888 ? 376 VAL A HG21 1 c 
ATOM   2799 H HG22 . VAL A 1 208 ? -5.181  4.089   21.051  1     16.89  ? 376 VAL A HG22 1 c 
ATOM   2800 H HG23 . VAL A 1 208 ? -6.675  3.947   20.54   1     16.911 ? 376 VAL A HG23 1 c 
ATOM   2801 N N    . ASP A 1 209 ? -6.669  0.141   19.279  1     16.22  ? 377 ASP A N    1 ? 
ATOM   2802 C CA   . ASP A 1 209 ? -7.867  -0.604  19.605  1     17.92  ? 377 ASP A CA   1 ? 
ATOM   2803 C C    . ASP A 1 209 ? -7.601  -1.507  20.816  1     18.731 ? 377 ASP A C    1 ? 
ATOM   2804 O O    . ASP A 1 209 ? -8.53   -1.891  21.485  1     17.728 ? 377 ASP A O    1 ? 
ATOM   2805 C CB   . ASP A 1 209 ? -8.259  -1.583  18.502  1     23.731 ? 377 ASP A CB   1 ? 
ATOM   2806 C CG   . ASP A 1 209 ? -8.852  -1.027  17.22   1     39.213 ? 377 ASP A CG   1 ? 
ATOM   2807 O OD1  . ASP A 1 209 ? -9.656  -0.087  17.317  1     46.163 ? 377 ASP A OD1  1 ? 
ATOM   2808 O OD2  . ASP A 1 209 ? -8.568  -1.624  16.141  1     50.266 ? 377 ASP A OD2  1 ? 
ATOM   2809 H H    . ASP A 1 209 ? -6.266  -0.019  18.476  1     17.11  ? 377 ASP A H    1 c 
ATOM   2810 H HA   . ASP A 1 209 ? -8.6    0.022   19.805  1     18.73  ? 377 ASP A HA   1 c 
ATOM   2811 H HB2  . ASP A 1 209 ? -7.46   -2.096  18.259  1     25.112 ? 377 ASP A HB2  1 c 
ATOM   2812 H HB3  . ASP A 1 209 ? -8.915  -2.217  18.861  1     25.014 ? 377 ASP A HB3  1 c 
ATOM   2813 N N    . ASP A 1 210 ? -6.333  -1.887  21.054  1     16.091 ? 378 ASP A N    1 ? 
ATOM   2814 C CA   . ASP A 1 210 ? -5.993  -2.747  22.192  1     16.623 ? 378 ASP A CA   1 ? 
ATOM   2815 C C    . ASP A 1 210 ? -6.028  -1.883  23.461  1     16.443 ? 378 ASP A C    1 ? 
ATOM   2816 O O    . ASP A 1 210 ? -5.288  -0.906  23.548  1     16.512 ? 378 ASP A O    1 ? 
ATOM   2817 C CB   . ASP A 1 210 ? -4.596  -3.314  22.024  1     18.647 ? 378 ASP A CB   1 ? 
ATOM   2818 C CG   . ASP A 1 210 ? -4.217  -4.426  22.998  1     20.168 ? 378 ASP A CG   1 ? 
ATOM   2819 O OD1  . ASP A 1 210 ? -4.552  -4.303  24.176  1     18.445 ? 378 ASP A OD1  1 ? 
ATOM   2820 O OD2  . ASP A 1 210 ? -3.59   -5.401  22.55   1     21.782 ? 378 ASP A OD2  1 ? 
ATOM   2821 H H    . ASP A 1 210 ? -5.666  -1.632  20.484  1     16.826 ? 378 ASP A H    1 c 
ATOM   2822 H HA   . ASP A 1 210 ? -6.645  -3.478  22.251  1     16.899 ? 378 ASP A HA   1 c 
ATOM   2823 H HB2  . ASP A 1 210 ? -4.524  -3.666  21.114  1     18.557 ? 378 ASP A HB2  1 c 
ATOM   2824 H HB3  . ASP A 1 210 ? -3.937  -2.595  22.112  1     18.485 ? 378 ASP A HB3  1 c 
ATOM   2825 N N    . PRO A 1 211 ? -6.798  -2.247  24.511  1     18.212 ? 379 PRO A N    1 ? 
ATOM   2826 C CA   . PRO A 1 211 ? -6.852  -1.418  25.726  1     17.458 ? 379 PRO A CA   1 ? 
ATOM   2827 C C    . PRO A 1 211 ? -5.501  -1.233  26.409  1     14.861 ? 379 PRO A C    1 ? 
ATOM   2828 O O    . PRO A 1 211 ? -5.32   -0.234  27.114  1     15.061 ? 379 PRO A O    1 ? 
ATOM   2829 C CB   . PRO A 1 211 ? -7.88   -2.118  26.673  1     22.592 ? 379 PRO A CB   1 ? 
ATOM   2830 C CG   . PRO A 1 211 ? -8.357  -3.32   25.907  1     24.826 ? 379 PRO A CG   1 ? 
ATOM   2831 C CD   . PRO A 1 211 ? -7.674  -3.417  24.577  1     21     ? 379 PRO A CD   1 ? 
ATOM   2832 H HA   . PRO A 1 211 ? -7.208  -0.53   25.47   1     17.896 ? 379 PRO A HA   1 c 
ATOM   2833 H HB2  . PRO A 1 211 ? -7.452  -2.393  27.514  1     21.77  ? 379 PRO A HB2  1 c 
ATOM   2834 H HB3  . PRO A 1 211 ? -8.631  -1.515  26.882  1     21.809 ? 379 PRO A HB3  1 c 
ATOM   2835 H HG2  . PRO A 1 211 ? -8.177  -4.132  26.425  1     23.39  ? 379 PRO A HG2  1 c 
ATOM   2836 H HG3  . PRO A 1 211 ? -9.325  -3.264  25.774  1     23.439 ? 379 PRO A HG3  1 c 
ATOM   2837 H HD2  . PRO A 1 211 ? -7.155  -4.248  24.513  1     21.08  ? 379 PRO A HD2  1 c 
ATOM   2838 H HD3  . PRO A 1 211 ? -8.334  -3.401  23.848  1     21.066 ? 379 PRO A HD3  1 c 
ATOM   2839 N N    . ALA A 1 212 ? -4.523  -2.147  26.197  1     15.492 ? 380 ALA A N    1 ? 
ATOM   2840 C CA   . ALA A 1 212 ? -3.211  -1.972  26.797  1     16.534 ? 380 ALA A CA   1 ? 
ATOM   2841 C C    . ALA A 1 212 ? -2.363  -0.924  26.069  1     16.148 ? 380 ALA A C    1 ? 
ATOM   2842 O O    . ALA A 1 212 ? -1.309  -0.527  26.6    1     16.274 ? 380 ALA A O    1 ? 
ATOM   2843 C CB   . ALA A 1 212 ? -2.475  -3.277  26.833  1     18.983 ? 380 ALA A CB   1 ? 
ATOM   2844 H H    . ALA A 1 212 ? -4.687  -2.893  25.696  1     15.608 ? 380 ALA A H    1 c 
ATOM   2845 H HA   . ALA A 1 212 ? -3.34   -1.66   27.735  1     16.661 ? 380 ALA A HA   1 c 
ATOM   2846 H HB1  . ALA A 1 212 ? -2.958  -3.909  27.392  1     18.203 ? 380 ALA A HB1  1 c 
ATOM   2847 H HB2  . ALA A 1 212 ? -2.402  -3.637  25.933  1     18.182 ? 380 ALA A HB2  1 c 
ATOM   2848 H HB3  . ALA A 1 212 ? -1.584  -3.143  27.198  1     18.186 ? 380 ALA A HB3  1 c 
ATOM   2849 N N    . TYR A 1 213 ? -2.833  -0.406  24.93   1     16.13  ? 381 TYR A N    1 ? 
ATOM   2850 C CA   . TYR A 1 213 ? -1.972  0.491   24.134  1     15.25  ? 381 TYR A CA   1 ? 
ATOM   2851 C C    . TYR A 1 213 ? -1.92   1.888   24.751  1     18.368 ? 381 TYR A C    1 ? 
ATOM   2852 O O    . TYR A 1 213 ? -0.844  2.392   25.082  1     15.329 ? 381 TYR A O    1 ? 
ATOM   2853 C CB   . TYR A 1 213 ? -2.477  0.572   22.7    1     15.846 ? 381 TYR A CB   1 ? 
ATOM   2854 C CG   . TYR A 1 213 ? -1.655  1.445   21.774  1     14.128 ? 381 TYR A CG   1 ? 
ATOM   2855 C CD1  . TYR A 1 213 ? -0.505  0.956   21.143  1     15.74  ? 381 TYR A CD1  1 ? 
ATOM   2856 C CD2  . TYR A 1 213 ? -2.127  2.692   21.421  1     14.066 ? 381 TYR A CD2  1 ? 
ATOM   2857 C CE1  . TYR A 1 213 ? 0.188   1.745   20.231  1     14.086 ? 381 TYR A CE1  1 ? 
ATOM   2858 C CE2  . TYR A 1 213 ? -1.448  3.484   20.51   1     13.668 ? 381 TYR A CE2  1 ? 
ATOM   2859 C CZ   . TYR A 1 213 ? -0.332  2.967   19.865  1     14.306 ? 381 TYR A CZ   1 ? 
ATOM   2860 O OH   . TYR A 1 213 ? 0.338   3.776   18.982  1     15.821 ? 381 TYR A OH   1 ? 
ATOM   2861 H H    . TYR A 1 213 ? -3.67   -0.607  24.625  1     15.927 ? 381 TYR A H    1 c 
ATOM   2862 H HA   . TYR A 1 213 ? -1.051  0.117   24.12   1     16.063 ? 381 TYR A HA   1 c 
ATOM   2863 H HB2  . TYR A 1 213 ? -2.503  -0.339  22.331  1     15.298 ? 381 TYR A HB2  1 c 
ATOM   2864 H HB3  . TYR A 1 213 ? -3.4    0.908   22.716  1     15.29  ? 381 TYR A HB3  1 c 
ATOM   2865 H HD1  . TYR A 1 213 ? -0.189  0.091   21.349  1     14.952 ? 381 TYR A HD1  1 c 
ATOM   2866 H HD2  . TYR A 1 213 ? -2.919  3.018   21.815  1     14.049 ? 381 TYR A HD2  1 c 
ATOM   2867 H HE1  . TYR A 1 213 ? 0.958   1.411   19.804  1     14.509 ? 381 TYR A HE1  1 c 
ATOM   2868 H HE2  . TYR A 1 213 ? -1.781  4.333   20.275  1     13.932 ? 381 TYR A HE2  1 c 
ATOM   2869 N N    . LEU A 1 214 ? -3.067  2.559   24.887  1     16.333 ? 382 LEU A N    1 ? 
ATOM   2870 C CA   . LEU A 1 214 ? -3.015  3.962   25.309  1     16.005 ? 382 LEU A CA   1 ? 
ATOM   2871 C C    . LEU A 1 214 ? -2.391  4.128   26.693  1     16.947 ? 382 LEU A C    1 ? 
ATOM   2872 O O    . LEU A 1 214 ? -1.587  5.034   26.85   1     16.141 ? 382 LEU A O    1 ? 
ATOM   2873 C CB   . LEU A 1 214 ? -4.328  4.711   25.208  1     16.857 ? 382 LEU A CB   1 ? 
ATOM   2874 C CG   . LEU A 1 214 ? -4.753  4.99    23.767  1     16.415 ? 382 LEU A CG   1 ? 
ATOM   2875 C CD1  . LEU A 1 214 ? -6.221  5.331   23.714  1     15.439 ? 382 LEU A CD1  1 ? 
ATOM   2876 C CD2  . LEU A 1 214 ? -3.871  6.059   23.151  1     17.587 ? 382 LEU A CD2  1 ? 
ATOM   2877 H H    . LEU A 1 214 ? -3.872  2.16    24.722  1     16.714 ? 382 LEU A H    1 c 
ATOM   2878 H HA   . LEU A 1 214 ? -2.385  4.405   24.687  1     16.412 ? 382 LEU A HA   1 c 
ATOM   2879 H HB2  . LEU A 1 214 ? -5.028  4.173   25.646  1     16.556 ? 382 LEU A HB2  1 c 
ATOM   2880 H HB3  . LEU A 1 214 ? -4.241  5.568   25.686  1     16.564 ? 382 LEU A HB3  1 c 
ATOM   2881 H HG   . LEU A 1 214 ? -4.619  4.157   23.248  1     16.53  ? 382 LEU A HG   1 c 
ATOM   2882 H HD11 . LEU A 1 214 ? -6.743  4.558   23.988  1     15.729 ? 382 LEU A HD11 1 c 
ATOM   2883 H HD12 . LEU A 1 214 ? -6.465  5.581   22.807  1     15.736 ? 382 LEU A HD12 1 c 
ATOM   2884 H HD13 . LEU A 1 214 ? -6.404  6.072   24.315  1     15.739 ? 382 LEU A HD13 1 c 
ATOM   2885 H HD21 . LEU A 1 214 ? -3.026  5.665   22.876  1     17.23  ? 382 LEU A HD21 1 c 
ATOM   2886 H HD22 . LEU A 1 214 ? -3.703  6.761   23.801  1     17.221 ? 382 LEU A HD22 1 c 
ATOM   2887 H HD23 . LEU A 1 214 ? -4.315  6.439   22.375  1     17.212 ? 382 LEU A HD23 1 c 
ATOM   2888 N N    . PRO A 1 215 ? -2.595  3.22    27.684  1     15.483 ? 383 PRO A N    1 ? 
ATOM   2889 C CA   . PRO A 1 215 ? -1.88   3.324   28.954  1     17.686 ? 383 PRO A CA   1 ? 
ATOM   2890 C C    . PRO A 1 215 ? -0.384  3.122   28.897  1     20.409 ? 383 PRO A C    1 ? 
ATOM   2891 O O    . PRO A 1 215 ? 0.254   3.232   29.931  1     21.666 ? 383 PRO A O    1 ? 
ATOM   2892 C CB   . PRO A 1 215 ? -2.529  2.28    29.865  1     17.103 ? 383 PRO A CB   1 ? 
ATOM   2893 C CG   . PRO A 1 215 ? -3.948  2.144   29.249  1     18.094 ? 383 PRO A CG   1 ? 
ATOM   2894 C CD   . PRO A 1 215 ? -3.649  2.21    27.728  1     17.341 ? 383 PRO A CD   1 ? 
ATOM   2895 H HA   . PRO A 1 215 ? -2.062  4.22    29.326  1     17.631 ? 383 PRO A HA   1 c 
ATOM   2896 H HB2  . PRO A 1 215 ? -2.043  1.422   29.831  1     17.463 ? 383 PRO A HB2  1 c 
ATOM   2897 H HB3  . PRO A 1 215 ? -2.573  2.599   30.797  1     17.45  ? 383 PRO A HB3  1 c 
ATOM   2898 H HG2  . PRO A 1 215 ? -4.362  1.29    29.494  1     17.702 ? 383 PRO A HG2  1 c 
ATOM   2899 H HG3  . PRO A 1 215 ? -4.53   2.88    29.53   1     17.702 ? 383 PRO A HG3  1 c 
ATOM   2900 H HD2  . PRO A 1 215 ? -3.329  1.348   27.39   1     17.023 ? 383 PRO A HD2  1 c 
ATOM   2901 H HD3  . PRO A 1 215 ? -4.443  2.492   27.221  1     17.028 ? 383 PRO A HD3  1 c 
ATOM   2902 N N    . ALA A 1 216 ? 0.142   2.666   27.762  1     18.703 ? 384 ALA A N    1 ? 
ATOM   2903 C CA   . ALA A 1 216 ? 1.576   2.414   27.636  1     16.57  ? 384 ALA A CA   1 ? 
ATOM   2904 C C    . ALA A 1 216 ? 2.306   3.52    26.869  1     16.901 ? 384 ALA A C    1 ? 
ATOM   2905 O O    . ALA A 1 216 ? 3.519   3.415   26.711  1     21.002 ? 384 ALA A O    1 ? 
ATOM   2906 C CB   . ALA A 1 216 ? 1.78    1.107   26.888  1     15.746 ? 384 ALA A CB   1 ? 
ATOM   2907 H H    . ALA A 1 216 ? -0.396  2.477   27.05   1     18.499 ? 384 ALA A H    1 c 
ATOM   2908 H HA   . ALA A 1 216 ? 1.978   2.338   28.545  1     16.909 ? 384 ALA A HA   1 c 
ATOM   2909 H HB1  . ALA A 1 216 ? 1.479   0.364   27.439  1     15.997 ? 384 ALA A HB1  1 c 
ATOM   2910 H HB2  . ALA A 1 216 ? 1.269   1.119   26.061  1     16.006 ? 384 ALA A HB2  1 c 
ATOM   2911 H HB3  . ALA A 1 216 ? 2.721   0.99    26.679  1     16.026 ? 384 ALA A HB3  1 c 
ATOM   2912 N N    . ILE A 1 217 ? 1.591   4.47    26.256  1     15.169 ? 385 ILE A N    1 ? 
ATOM   2913 C CA   . ILE A 1 217 ? 2.249   5.456   25.402  1     15.999 ? 385 ILE A CA   1 ? 
ATOM   2914 C C    . ILE A 1 217 ? 1.994   6.876   25.9    1     17.04  ? 385 ILE A C    1 ? 
ATOM   2915 O O    . ILE A 1 217 ? 0.982   7.18    26.584  1     17.87  ? 385 ILE A O    1 ? 
ATOM   2916 C CB   . ILE A 1 217 ? 1.868   5.308   23.922  1     15.14  ? 385 ILE A CB   1 ? 
ATOM   2917 C CG1  . ILE A 1 217 ? 0.439   5.765   23.632  1     18.528 ? 385 ILE A CG1  1 ? 
ATOM   2918 C CG2  . ILE A 1 217 ? 2.09    3.873   23.455  1     15.352 ? 385 ILE A CG2  1 ? 
ATOM   2919 C CD1  . ILE A 1 217 ? 0.12    6.058   22.178  1     19.14  ? 385 ILE A CD1  1 ? 
ATOM   2920 H H    . ILE A 1 217 ? 0.685   4.512   26.365  1     15.773 ? 385 ILE A H    1 c 
ATOM   2921 H HA   . ILE A 1 217 ? 3.211   5.302   25.461  1     15.88  ? 385 ILE A HA   1 c 
ATOM   2922 H HB   . ILE A 1 217 ? 2.469   5.883   23.406  1     15.928 ? 385 ILE A HB   1 c 
ATOM   2923 H HG12 . ILE A 1 217 ? -0.174  5.07    23.946  1     17.825 ? 385 ILE A HG12 1 c 
ATOM   2924 H HG13 . ILE A 1 217 ? 0.254   6.573   24.149  1     17.826 ? 385 ILE A HG13 1 c 
ATOM   2925 H HG21 . ILE A 1 217 ? 1.977   3.822   22.492  1     15.325 ? 385 ILE A HG21 1 c 
ATOM   2926 H HG22 . ILE A 1 217 ? 1.444   3.286   23.884  1     15.298 ? 385 ILE A HG22 1 c 
ATOM   2927 H HG23 . ILE A 1 217 ? 2.989   3.589   23.689  1     15.298 ? 385 ILE A HG23 1 c 
ATOM   2928 H HD11 . ILE A 1 217 ? 0.52    6.911   21.924  1     18.914 ? 385 ILE A HD11 1 c 
ATOM   2929 H HD12 . ILE A 1 217 ? -0.848  6.11    22.062  1     18.921 ? 385 ILE A HD12 1 c 
ATOM   2930 H HD13 . ILE A 1 217 ? 0.475   5.351   21.608  1     18.873 ? 385 ILE A HD13 1 c 
ATOM   2931 N N    . ASP A 1 218 ? 2.893   7.773   25.478  1     14.205 ? 386 ASP A N    1 ? 
ATOM   2932 C CA   . ASP A 1 218 ? 2.748   9.19    25.745  1     15.449 ? 386 ASP A CA   1 ? 
ATOM   2933 C C    . ASP A 1 218 ? 2.564   9.988   24.46   1     13.624 ? 386 ASP A C    1 ? 
ATOM   2934 O O    . ASP A 1 218 ? 2.218   11.14   24.523  1     15.214 ? 386 ASP A O    1 ? 
ATOM   2935 C CB   . ASP A 1 218 ? 3.936   9.77    26.476  1     15.626 ? 386 ASP A CB   1 ? 
ATOM   2936 C CG   . ASP A 1 218 ? 4.228   8.962   27.726  1     18.192 ? 386 ASP A CG   1 ? 
ATOM   2937 O OD1  . ASP A 1 218 ? 3.365   8.978   28.602  1     16.966 ? 386 ASP A OD1  1 ? 
ATOM   2938 O OD2  . ASP A 1 218 ? 5.226   8.244   27.729  1     16.285 ? 386 ASP A OD2  1 ? 
ATOM   2939 H H    . ASP A 1 218 ? 3.642   7.484   25.042  1     15.123 ? 386 ASP A H    1 c 
ATOM   2940 H HA   . ASP A 1 218 ? 1.957   9.331   26.312  1     14.923 ? 386 ASP A HA   1 c 
ATOM   2941 H HB2  . ASP A 1 218 ? 4.725   9.759   25.894  1     16.124 ? 386 ASP A HB2  1 c 
ATOM   2942 H HB3  . ASP A 1 218 ? 3.747   10.698  26.732  1     16.135 ? 386 ASP A HB3  1 c 
ATOM   2943 N N    . GLY A 1 219 ? 2.751   9.352   23.304  1     14.825 ? 387 GLY A N    1 ? 
ATOM   2944 C CA   . GLY A 1 219 ? 2.623   10.072  22.047  1     14.486 ? 387 GLY A CA   1 ? 
ATOM   2945 C C    . GLY A 1 219 ? 2.691   9.062   20.906  1     15.297 ? 387 GLY A C    1 ? 
ATOM   2946 O O    . GLY A 1 219 ? 2.891   7.904   21.164  1     15.287 ? 387 GLY A O    1 ? 
ATOM   2947 H H    . GLY A 1 219 ? 2.957   8.463   23.285  1     14.47  ? 387 GLY A H    1 c 
ATOM   2948 H HA2  . GLY A 1 219 ? 1.763   10.547  22.026  1     14.796 ? 387 GLY A HA2  1 c 
ATOM   2949 H HA3  . GLY A 1 219 ? 3.351   10.732  21.963  1     14.753 ? 387 GLY A HA3  1 c 
ATOM   2950 N N    . LEU A 1 220 ? 2.501   9.528   19.68   1     14.151 ? 388 LEU A N    1 ? 
ATOM   2951 C CA   . LEU A 1 220 ? 2.503   8.642   18.516  1     14.157 ? 388 LEU A CA   1 ? 
ATOM   2952 C C    . LEU A 1 220 ? 3.141   9.444   17.403  1     14.976 ? 388 LEU A C    1 ? 
ATOM   2953 O O    . LEU A 1 220 ? 2.753   10.608  17.223  1     16.292 ? 388 LEU A O    1 ? 
ATOM   2954 C CB   . LEU A 1 220 ? 1.051   8.319   18.158  1     16.18  ? 388 LEU A CB   1 ? 
ATOM   2955 C CG   . LEU A 1 220 ? 0.756   7.719   16.775  1     17.762 ? 388 LEU A CG   1 ? 
ATOM   2956 C CD1  . LEU A 1 220 ? 1.29    6.345   16.687  1     18.817 ? 388 LEU A CD1  1 ? 
ATOM   2957 C CD2  . LEU A 1 220 ? -0.717  7.813   16.411  1     18.884 ? 388 LEU A CD2  1 ? 
ATOM   2958 H H    . LEU A 1 220 ? 2.358   10.422  19.557  1     14.422 ? 388 LEU A H    1 c 
ATOM   2959 H HA   . LEU A 1 220 ? 3.015   7.816   18.705  1     14.67  ? 388 LEU A HA   1 c 
ATOM   2960 H HB2  . LEU A 1 220 ? 0.704   7.698   18.84   1     16.046 ? 388 LEU A HB2  1 c 
ATOM   2961 H HB3  . LEU A 1 220 ? 0.527   9.148   18.249  1     16.048 ? 388 LEU A HB3  1 c 
ATOM   2962 H HG   . LEU A 1 220 ? 1.246   8.257   16.106  1     17.848 ? 388 LEU A HG   1 c 
ATOM   2963 H HD11 . LEU A 1 220 ? 2.259   6.369   16.751  1     18.446 ? 388 LEU A HD11 1 c 
ATOM   2964 H HD12 . LEU A 1 220 ? 1.033   5.95    15.837  1     18.474 ? 388 LEU A HD12 1 c 
ATOM   2965 H HD13 . LEU A 1 220 ? 0.931   5.81    17.414  1     18.448 ? 388 LEU A HD13 1 c 
ATOM   2966 H HD21 . LEU A 1 220 ? -1.03   8.722   16.552  1     18.523 ? 388 LEU A HD21 1 c 
ATOM   2967 H HD22 . LEU A 1 220 ? -1.228  7.205   16.97   1     18.525 ? 388 LEU A HD22 1 c 
ATOM   2968 H HD23 . LEU A 1 220 ? -0.837  7.571   15.478  1     18.536 ? 388 LEU A HD23 1 c 
ATOM   2969 N N    . GLY A 1 221 ? 4.043   8.809   16.664  1     14.983 ? 389 GLY A N    1 ? 
ATOM   2970 C CA   . GLY A 1 221 ? 4.588   9.396   15.453  1     16.579 ? 389 GLY A CA   1 ? 
ATOM   2971 C C    . GLY A 1 221 ? 3.874   8.76    14.261  1     16.595 ? 389 GLY A C    1 ? 
ATOM   2972 O O    . GLY A 1 221 ? 3.599   7.582   14.294  1     17.869 ? 389 GLY A O    1 ? 
ATOM   2973 H H    . GLY A 1 221 ? 4.336   7.982   16.919  1     15.314 ? 389 GLY A H    1 c 
ATOM   2974 H HA2  . GLY A 1 221 ? 4.455   10.368  15.459  1     16.188 ? 389 GLY A HA2  1 c 
ATOM   2975 H HA3  . GLY A 1 221 ? 5.551   9.214   15.404  1     16.205 ? 389 GLY A HA3  1 c 
ATOM   2976 N N    . MET A 1 222 ? 3.46    9.597   13.303  1     15.338 ? 390 MET A N    1 ? 
ATOM   2977 C CA   . MET A 1 222 ? 2.731   9.097   12.157  1     16.186 ? 390 MET A CA   1 ? 
ATOM   2978 C C    . MET A 1 222 ? 3.355   9.686   10.918  1     17.037 ? 390 MET A C    1 ? 
ATOM   2979 O O    . MET A 1 222 ? 3.396   10.895  10.787  1     17.874 ? 390 MET A O    1 ? 
ATOM   2980 C CB   . MET A 1 222 ? 1.269   9.557   12.18   1     15.588 ? 390 MET A CB   1 ? 
ATOM   2981 C CG   . MET A 1 222 ? 0.384   8.785   13.165  1     18.538 ? 390 MET A CG   1 ? 
ATOM   2982 S SD   . MET A 1 222 ? 0.337   7.035   12.734  1     20.744 ? 390 MET A SD   1 ? 
ATOM   2983 C CE   . MET A 1 222 ? -0.449  7.083   11.122  1     24.294 ? 390 MET A CE   1 ? 
ATOM   2984 H H    . MET A 1 222 ? 3.634   10.493  13.365  1     15.835 ? 390 MET A H    1 c 
ATOM   2985 H HA   . MET A 1 222 ? 2.788   8.111   12.125  1     16.12  ? 390 MET A HA   1 c 
ATOM   2986 H HB2  . MET A 1 222 ? 1.248   10.508  12.417  1     16.368 ? 390 MET A HB2  1 c 
ATOM   2987 H HB3  . MET A 1 222 ? 0.896   9.469   11.278  1     16.429 ? 390 MET A HB3  1 c 
ATOM   2988 H HG2  . MET A 1 222 ? 0.735   8.884   14.069  1     18.174 ? 390 MET A HG2  1 c 
ATOM   2989 H HG3  . MET A 1 222 ? -0.524  9.145   13.146  1     18.177 ? 390 MET A HG3  1 c 
ATOM   2990 H HE1  . MET A 1 222 ? -0.727  6.184   10.869  1     23.289 ? 390 MET A HE1  1 c 
ATOM   2991 H HE2  . MET A 1 222 ? -1.229  7.668   11.158  1     23.325 ? 390 MET A HE2  1 c 
ATOM   2992 H HE3  . MET A 1 222 ? 0.183   7.422   10.462  1     23.278 ? 390 MET A HE3  1 c 
ATOM   2993 N N    . GLU A 1 223 ? 3.77    8.796   10.004  1     18.327 ? 391 GLU A N    1 ? 
ATOM   2994 C CA   . GLU A 1 223 ? 4.328   9.223   8.742   1     17.991 ? 391 GLU A CA   1 ? 
ATOM   2995 C C    . GLU A 1 223 ? 3.236   9.118   7.687   1     16.937 ? 391 GLU A C    1 ? 
ATOM   2996 O O    . GLU A 1 223 ? 2.333   8.255   7.763   1     18.287 ? 391 GLU A O    1 ? 
ATOM   2997 C CB   . GLU A 1 223 ? 5.487   8.307   8.363   1     18.28  ? 391 GLU A CB   1 ? 
ATOM   2998 C CG   . GLU A 1 223 ? 6.735   8.427   9.235   1     19.572 ? 391 GLU A CG   1 ? 
ATOM   2999 C CD   . GLU A 1 223 ? 7.754   7.438   8.698   1     23.721 ? 391 GLU A CD   1 ? 
ATOM   3000 O OE1  . GLU A 1 223 ? 8.818   7.89    8.157   1     22.267 ? 391 GLU A OE1  1 ? 
ATOM   3001 O OE2  . GLU A 1 223 ? 7.468   6.228   8.796   1     21.048 ? 391 GLU A OE2  1 ? 
ATOM   3002 H H    . GLU A 1 223 ? 3.701   7.901   10.174  1     17.913 ? 391 GLU A H    1 c 
ATOM   3003 H HA   . GLU A 1 223 ? 4.642   10.151  8.82    1     17.888 ? 391 GLU A HA   1 c 
ATOM   3004 H HB2  . GLU A 1 223 ? 5.169   7.38    8.394   1     18.536 ? 391 GLU A HB2  1 c 
ATOM   3005 H HB3  . GLU A 1 223 ? 5.744   8.499   7.437   1     18.523 ? 391 GLU A HB3  1 c 
ATOM   3006 H HG2  . GLU A 1 223 ? 7.098   9.337   9.183   1     20.139 ? 391 GLU A HG2  1 c 
ATOM   3007 H HG3  . GLU A 1 223 ? 6.52    8.209   10.167  1     20.139 ? 391 GLU A HG3  1 c 
ATOM   3008 N N    . ASP A 1 224 ? 3.283   10.024  6.708   1     17.756 ? 392 ASP A N    1 ? 
ATOM   3009 C CA   . ASP A 1 224 ? 2.631   9.82    5.433   1     17.746 ? 392 ASP A CA   1 ? 
ATOM   3010 C C    . ASP A 1 224 ? 1.114   9.861   5.512   1     17.045 ? 392 ASP A C    1 ? 
ATOM   3011 O O    . ASP A 1 224 ? 0.444   9.265   4.672   1     19.99  ? 392 ASP A O    1 ? 
ATOM   3012 C CB   . ASP A 1 224 ? 3.088   8.549   4.759   1     16.999 ? 392 ASP A CB   1 ? 
ATOM   3013 C CG   . ASP A 1 224 ? 4.508   8.581   4.228   1     18.356 ? 392 ASP A CG   1 ? 
ATOM   3014 O OD1  . ASP A 1 224 ? 4.76    9.425   3.346   1     17.646 ? 392 ASP A OD1  1 ? 
ATOM   3015 O OD2  . ASP A 1 224 ? 5.355   7.809   4.741   1     19.588 ? 392 ASP A OD2  1 ? 
ATOM   3016 H H    . ASP A 1 224 ? 3.738   10.805  6.843   1     17.561 ? 392 ASP A H    1 c 
ATOM   3017 H HA   . ASP A 1 224 ? 2.911   10.554  4.842   1     17.478 ? 392 ASP A HA   1 c 
ATOM   3018 H HB2  . ASP A 1 224 ? 3.004   7.784   5.362   1     17.495 ? 392 ASP A HB2  1 c 
ATOM   3019 H HB3  . ASP A 1 224 ? 2.517   8.365   3.986   1     17.522 ? 392 ASP A HB3  1 c 
ATOM   3020 N N    . MET A 1 225 ? 0.569   10.631  6.447   1     17.401 ? 393 MET A N    1 ? 
ATOM   3021 C CA   . MET A 1 225 ? -0.868  10.765  6.539   1     15.713 ? 393 MET A CA   1 ? 
ATOM   3022 C C    . MET A 1 225 ? -1.445  11.691  5.466   1     15.012 ? 393 MET A C    1 ? 
ATOM   3023 O O    . MET A 1 225 ? -2.646  11.602  5.195   1     17.794 ? 393 MET A O    1 ? 
ATOM   3024 C CB   . MET A 1 225 ? -1.288  11.293  7.922   1     17.146 ? 393 MET A CB   1 ? 
ATOM   3025 C CG   . MET A 1 225 ? -1.178  10.202  9.012   1     20.722 ? 393 MET A CG   1 ? 
ATOM   3026 S SD   . MET A 1 225 ? -1.952  10.696  10.565  1     19.807 ? 393 MET A SD   1 ? 
ATOM   3027 C CE   . MET A 1 225 ? -1.026  12.134  11.068  1     19.28  ? 393 MET A CE   1 ? 
ATOM   3028 H H    . MET A 1 225 ? 1.098   11.092  7.034   1     16.938 ? 393 MET A H    1 c 
ATOM   3029 H HA   . MET A 1 225 ? -1.267  9.867   6.41    1     16.193 ? 393 MET A HA   1 c 
ATOM   3030 H HB2  . MET A 1 225 ? -0.722  12.055  8.162   1     17.54  ? 393 MET A HB2  1 c 
ATOM   3031 H HB3  . MET A 1 225 ? -2.216  11.608  7.875   1     17.539 ? 393 MET A HB3  1 c 
ATOM   3032 H HG2  . MET A 1 225 ? -1.606  9.382   8.695   1     19.623 ? 393 MET A HG2  1 c 
ATOM   3033 H HG3  . MET A 1 225 ? -0.235  10.005  9.179   1     19.644 ? 393 MET A HG3  1 c 
ATOM   3034 H HE1  . MET A 1 225 ? -1.201  12.32   12.009  1     19.396 ? 393 MET A HE1  1 c 
ATOM   3035 H HE2  . MET A 1 225 ? -0.074  11.968  10.94   1     19.407 ? 393 MET A HE2  1 c 
ATOM   3036 H HE3  . MET A 1 225 ? -1.298  12.9    10.529  1     19.407 ? 393 MET A HE3  1 c 
ATOM   3037 N N    . TYR A 1 226 ? -0.637  12.621  4.951   1     16.528 ? 394 TYR A N    1 ? 
ATOM   3038 C CA   . TYR A 1 226 ? -1.109  13.682  4.057   1     16.079 ? 394 TYR A CA   1 ? 
ATOM   3039 C C    . TYR A 1 226 ? -0.397  13.653  2.702   1     18.515 ? 394 TYR A C    1 ? 
ATOM   3040 O O    . TYR A 1 226 ? -1.081  13.556  1.671   1     16.844 ? 394 TYR A O    1 ? 
ATOM   3041 C CB   . TYR A 1 226 ? -0.966  15.045  4.738   1     16.614 ? 394 TYR A CB   1 ? 
ATOM   3042 C CG   . TYR A 1 226 ? -1.66   15.111  6.085   1     16.066 ? 394 TYR A CG   1 ? 
ATOM   3043 C CD1  . TYR A 1 226 ? -3.056  15.051  6.179   1     16.685 ? 394 TYR A CD1  1 ? 
ATOM   3044 C CD2  . TYR A 1 226 ? -0.94   15.166  7.277   1     18.5   ? 394 TYR A CD2  1 ? 
ATOM   3045 C CE1  . TYR A 1 226 ? -3.715  15.073  7.393   1     18.909 ? 394 TYR A CE1  1 ? 
ATOM   3046 C CE2  . TYR A 1 226 ? -1.593  15.187  8.499   1     20.197 ? 394 TYR A CE2  1 ? 
ATOM   3047 C CZ   . TYR A 1 226 ? -2.976  15.148  8.569   1     20.927 ? 394 TYR A CZ   1 ? 
ATOM   3048 O OH   . TYR A 1 226 ? -3.525  15.199  9.83    1     19.054 ? 394 TYR A OH   1 ? 
ATOM   3049 H H    . TYR A 1 226 ? 0.249   12.61   5.172   1     16.08  ? 394 TYR A H    1 c 
ATOM   3050 H HA   . TYR A 1 226 ? -2.077  13.535  3.888   1     16.688 ? 394 TYR A HA   1 c 
ATOM   3051 H HB2  . TYR A 1 226 ? -0.01   15.237  4.859   1     16.388 ? 394 TYR A HB2  1 c 
ATOM   3052 H HB3  . TYR A 1 226 ? -1.345  15.733  4.147   1     16.37  ? 394 TYR A HB3  1 c 
ATOM   3053 H HD1  . TYR A 1 226 ? -3.563  14.995  5.388   1     17.105 ? 394 TYR A HD1  1 c 
ATOM   3054 H HD2  . TYR A 1 226 ? 0       15.198  7.253   1     18.257 ? 394 TYR A HD2  1 c 
ATOM   3055 H HE1  . TYR A 1 226 ? -4.656  15.05   7.424   1     18.787 ? 394 TYR A HE1  1 c 
ATOM   3056 H HE2  . TYR A 1 226 ? -1.091  15.248  9.293   1     19.884 ? 394 TYR A HE2  1 c 
ATOM   3057 N N    . TRP A 1 227 ? 0.942   13.714  2.71    1     17.049 ? 395 TRP A N    1 ? 
ATOM   3058 C CA   . TRP A 1 227 ? 1.756   13.785  1.502   1     19.215 ? 395 TRP A CA   1 ? 
ATOM   3059 C C    . TRP A 1 227 ? 2.961   12.869  1.6     1     19.805 ? 395 TRP A C    1 ? 
ATOM   3060 O O    . TRP A 1 227 ? 3.715   12.967  2.569   1     18.624 ? 395 TRP A O    1 ? 
ATOM   3061 C CB   . TRP A 1 227 ? 2.232   15.223  1.23    1     19.416 ? 395 TRP A CB   1 ? 
ATOM   3062 C CG   . TRP A 1 227 ? 1.066   16.075  0.848   1     17.724 ? 395 TRP A CG   1 ? 
ATOM   3063 C CD1  . TRP A 1 227 ? 0.266   16.804  1.68    1     18.965 ? 395 TRP A CD1  1 ? 
ATOM   3064 C CD2  . TRP A 1 227 ? 0.439   16.13   -0.445  1     19.126 ? 395 TRP A CD2  1 ? 
ATOM   3065 N NE1  . TRP A 1 227 ? -0.754  17.37   0.979   1     18.594 ? 395 TRP A NE1  1 ? 
ATOM   3066 C CE2  . TRP A 1 227 ? -0.705  16.948  -0.317  1     21.051 ? 395 TRP A CE2  1 ? 
ATOM   3067 C CE3  . TRP A 1 227 ? 0.745   15.58   -1.692  1     19.17  ? 395 TRP A CE3  1 ? 
ATOM   3068 C CZ2  . TRP A 1 227 ? -1.544  17.244  -1.395  1     21.299 ? 395 TRP A CZ2  1 ? 
ATOM   3069 C CZ3  . TRP A 1 227 ? -0.08   15.878  -2.756  1     19.557 ? 395 TRP A CZ3  1 ? 
ATOM   3070 C CH2  . TRP A 1 227 ? -1.226  16.654  -2.596  1     19.44  ? 395 TRP A CH2  1 ? 
ATOM   3071 H H    . TRP A 1 227 ? 1.373   13.719  3.516   1     17.842 ? 395 TRP A H    1 c 
ATOM   3072 H HA   . TRP A 1 227 ? 1.2     13.495  0.732   1     18.878 ? 395 TRP A HA   1 c 
ATOM   3073 H HB2  . TRP A 1 227 ? 2.646   15.583  2.044   1     18.966 ? 395 TRP A HB2  1 c 
ATOM   3074 H HB3  . TRP A 1 227 ? 2.882   15.213  0.496   1     18.97  ? 395 TRP A HB3  1 c 
ATOM   3075 H HD1  . TRP A 1 227 ? 0.421   16.943  2.6     1     18.613 ? 395 TRP A HD1  1 c 
ATOM   3076 H HE1  . TRP A 1 227 ? -1.371  17.874  1.318   1     19.269 ? 395 TRP A HE1  1 c 
ATOM   3077 H HE3  . TRP A 1 227 ? 1.503   15.034  -1.803  1     19.259 ? 395 TRP A HE3  1 c 
ATOM   3078 H HZ2  . TRP A 1 227 ? -2.309  17.783  -1.294  1     20.745 ? 395 TRP A HZ2  1 c 
ATOM   3079 H HZ3  . TRP A 1 227 ? 0.098   15.493  -3.598  1     19.449 ? 395 TRP A HZ3  1 c 
ATOM   3080 H HH2  . TRP A 1 227 ? -1.762  16.835  -3.347  1     19.884 ? 395 TRP A HH2  1 c 
ATOM   3081 N N    . SER A 1 228 ? 3.095   11.968  0.591   1     17.307 ? 396 SER A N    1 ? 
ATOM   3082 C CA   . SER A 1 228 ? 4.154   10.985  0.525   1     20.388 ? 396 SER A CA   1 ? 
ATOM   3083 C C    . SER A 1 228 ? 4.967   11.23   -0.747  1     19.068 ? 396 SER A C    1 ? 
ATOM   3084 O O    . SER A 1 228 ? 4.513   10.902  -1.847  1     21.309 ? 396 SER A O    1 ? 
ATOM   3085 C CB   . SER A 1 228 ? 3.602   9.583   0.526   1     23.999 ? 396 SER A CB   1 ? 
ATOM   3086 O OG   . SER A 1 228 ? 2.695   9.442   1.613   1     23.8   ? 396 SER A OG   1 ? 
ATOM   3087 H H    . SER A 1 228 ? 2.485   11.981  -0.089  1     18.559 ? 396 SER A H    1 c 
ATOM   3088 H HA   . SER A 1 228 ? 4.746   11.094  1.31    1     20.083 ? 396 SER A HA   1 c 
ATOM   3089 H HB2  . SER A 1 228 ? 3.134   9.41    -0.313  1     23.05  ? 396 SER A HB2  1 c 
ATOM   3090 H HB3  . SER A 1 228 ? 4.33    8.942   0.617   1     23.073 ? 396 SER A HB3  1 c 
ATOM   3091 N N    . ASP A 1 229 ? 6.123   11.871  -0.584  1     19.772 ? 397 ASP A N    1 ? 
ATOM   3092 C CA   . ASP A 1 229 ? 6.981   12.271  -1.68   1     21.309 ? 397 ASP A CA   1 ? 
ATOM   3093 C C    . ASP A 1 229 ? 6.169   13.063  -2.708  1     19.068 ? 397 ASP A C    1 ? 
ATOM   3094 O O    . ASP A 1 229 ? 6.212   12.787  -3.911  1     21.379 ? 397 ASP A O    1 ? 
ATOM   3095 C CB   . ASP A 1 229 ? 7.757   11.081  -2.212  1     23.366 ? 397 ASP A CB   1 ? 
ATOM   3096 C CG   . ASP A 1 229 ? 8.697   10.411  -1.206  1     24.266 ? 397 ASP A CG   1 ? 
ATOM   3097 O OD1  . ASP A 1 229 ? 9.022   11.007  -0.167  1     26.993 ? 397 ASP A OD1  1 ? 
ATOM   3098 O OD2  . ASP A 1 229 ? 9.144   9.331   -1.489  1     28.068 ? 397 ASP A OD2  1 ? 
ATOM   3099 H H    . ASP A 1 229 ? 6.392   12.079  0.264   1     19.916 ? 397 ASP A H    1 c 
ATOM   3100 H HA   . ASP A 1 229 ? 7.656   12.88   -1.312  1     21.003 ? 397 ASP A HA   1 c 
ATOM   3101 H HB2  . ASP A 1 229 ? 7.123   10.407  -2.533  1     23.055 ? 397 ASP A HB2  1 c 
ATOM   3102 H HB3  . ASP A 1 229 ? 8.295   11.375  -2.976  1     23.063 ? 397 ASP A HB3  1 c 
ATOM   3103 N N    . ASP A 1 230 ? 5.408   14.034  -2.208  1     17.587 ? 398 ASP A N    1 ? 
ATOM   3104 C CA   . ASP A 1 230 ? 4.589   14.939  -3.017  1     16.939 ? 398 ASP A CA   1 ? 
ATOM   3105 C C    . ASP A 1 230 ? 3.44    14.237  -3.749  1     18.995 ? 398 ASP A C    1 ? 
ATOM   3106 O O    . ASP A 1 230 ? 2.89    14.82   -4.673  1     17.853 ? 398 ASP A O    1 ? 
ATOM   3107 C CB   . ASP A 1 230 ? 5.433   15.81   -3.938  1     16.7   ? 398 ASP A CB   1 ? 
ATOM   3108 C CG   . ASP A 1 230 ? 6.117   16.959  -3.227  1     18.196 ? 398 ASP A CG   1 ? 
ATOM   3109 O OD1  . ASP A 1 230 ? 5.361   17.86   -2.841  1     20.037 ? 398 ASP A OD1  1 ? 
ATOM   3110 O OD2  . ASP A 1 230 ? 7.356   16.884  -3.046  1     19.766 ? 398 ASP A OD2  1 ? 
ATOM   3111 H H    . ASP A 1 230 ? 5.401   14.155  -1.302  1     17.813 ? 398 ASP A H    1 c 
ATOM   3112 H HA   . ASP A 1 230 ? 4.171   15.574  -2.392  1     17.397 ? 398 ASP A HA   1 c 
ATOM   3113 H HB2  . ASP A 1 230 ? 6.132   15.275  -4.364  1     17.142 ? 398 ASP A HB2  1 c 
ATOM   3114 H HB3  . ASP A 1 230 ? 4.879   16.196  -4.647  1     17.116 ? 398 ASP A HB3  1 c 
ATOM   3115 N N    . VAL A 1 231 ? 3.019   13.06   -3.243  1     15.558 ? 399 VAL A N    1 ? 
ATOM   3116 C CA   . VAL A 1 231 ? 1.814   12.377  -3.705  1     17.235 ? 399 VAL A CA   1 ? 
ATOM   3117 C C    . VAL A 1 231 ? 0.833   12.277  -2.546  1     19.639 ? 399 VAL A C    1 ? 
ATOM   3118 O O    . VAL A 1 231 ? 1.223   11.903  -1.43   1     18.41  ? 399 VAL A O    1 ? 
ATOM   3119 C CB   . VAL A 1 231 ? 2.165   10.979  -4.25   1     17.654 ? 399 VAL A CB   1 ? 
ATOM   3120 C CG1  . VAL A 1 231 ? 0.894   10.284  -4.728  1     18.579 ? 399 VAL A CG1  1 ? 
ATOM   3121 C CG2  . VAL A 1 231 ? 3.197   11.047  -5.363  1     19.725 ? 399 VAL A CG2  1 ? 
ATOM   3122 H H    . VAL A 1 231 ? 3.49    12.675  -2.564  1     16.732 ? 399 VAL A H    1 c 
ATOM   3123 H HA   . VAL A 1 231 ? 1.407   12.899  -4.422  1     17.425 ? 399 VAL A HA   1 c 
ATOM   3124 H HB   . VAL A 1 231 ? 2.541   10.456  -3.505  1     18.13  ? 399 VAL A HB   1 c 
ATOM   3125 H HG11 . VAL A 1 231 ? 0.296   10.937  -5.13   1     18.294 ? 399 VAL A HG11 1 c 
ATOM   3126 H HG12 . VAL A 1 231 ? 0.45    9.862   -3.974  1     18.309 ? 399 VAL A HG12 1 c 
ATOM   3127 H HG13 . VAL A 1 231 ? 1.119   9.606   -5.387  1     18.315 ? 399 VAL A HG13 1 c 
ATOM   3128 H HG21 . VAL A 1 231 ? 3.316   10.165  -5.753  1     19.079 ? 399 VAL A HG21 1 c 
ATOM   3129 H HG22 . VAL A 1 231 ? 4.046   11.355  -5.002  1     19.067 ? 399 VAL A HG22 1 c 
ATOM   3130 H HG23 . VAL A 1 231 ? 2.895   11.666  -6.049  1     19.083 ? 399 VAL A HG23 1 c 
ATOM   3131 N N    . ALA A 1 232 ? -0.435  12.597  -2.799  1     19.209 ? 400 ALA A N    1 ? 
ATOM   3132 C CA   . ALA A 1 232 ? -1.423  12.646  -1.749  1     21.193 ? 400 ALA A CA   1 ? 
ATOM   3133 C C    . ALA A 1 232 ? -1.68   11.254  -1.191  1     23.432 ? 400 ALA A C    1 ? 
ATOM   3134 O O    . ALA A 1 232 ? -1.769  10.251  -1.933  1     20.544 ? 400 ALA A O    1 ? 
ATOM   3135 C CB   . ALA A 1 232 ? -2.7    13.277  -2.257  1     20.133 ? 400 ALA A CB   1 ? 
ATOM   3136 H H    . ALA A 1 232 ? -0.693  12.784  -3.656  1     19.71  ? 400 ALA A H    1 c 
ATOM   3137 H HA   . ALA A 1 232 ? -1.058  13.215  -1.016  1     20.935 ? 400 ALA A HA   1 c 
ATOM   3138 H HB1  . ALA A 1 232 ? -2.514  14.167  -2.598  1     20.441 ? 400 ALA A HB1  1 c 
ATOM   3139 H HB2  . ALA A 1 232 ? -3.072  12.732  -2.972  1     20.445 ? 400 ALA A HB2  1 c 
ATOM   3140 H HB3  . ALA A 1 232 ? -3.346  13.338  -1.533  1     20.461 ? 400 ALA A HB3  1 c 
ATOM   3141 N N    . CYS A 1 233 ? -1.757  11.197  0.149   1     20.489 ? 401 CYS A N    1 ? 
ATOM   3142 C CA   . CYS A 1 233 ? -2.221  9.993   0.827   1     21.337 ? 401 CYS A CA   1 ? 
ATOM   3143 C C    . CYS A 1 233 ? -3.739  10.066  0.807   1     24.506 ? 401 CYS A C    1 ? 
ATOM   3144 O O    . CYS A 1 233 ? -4.359  10.577  1.751   1     20.511 ? 401 CYS A O    1 ? 
ATOM   3145 C CB   . CYS A 1 233 ? -1.636  9.875   2.221   1     21.164 ? 401 CYS A CB   1 ? 
ATOM   3146 S SG   . CYS A 1 233 ? -1.596  8.167   2.893   1     26.83  ? 401 CYS A SG   1 ? 
ATOM   3147 H H    . CYS A 1 233 ? -1.517  11.92   0.653   1     21.328 ? 401 CYS A H    1 c 
ATOM   3148 H HA   . CYS A 1 233 ? -1.932  9.205   0.3     1     21.732 ? 401 CYS A HA   1 c 
ATOM   3149 H HB2  . CYS A 1 233 ? -0.715  10.218  2.205   1     22.164 ? 401 CYS A HB2  1 c 
ATOM   3150 H HB3  . CYS A 1 233 ? -2.152  10.438  2.838   1     22.144 ? 401 CYS A HB3  1 c 
ATOM   3151 N N    . ASP A 1 234 ? -4.321  9.576   -0.299  1     23.124 ? 402 ASP A N    1 ? 
ATOM   3152 C CA   . ASP A 1 234 ? -5.736  9.768   -0.537  1     26.909 ? 402 ASP A CA   1 ? 
ATOM   3153 C C    . ASP A 1 234 ? -6.453  8.428   -0.639  1     29.086 ? 402 ASP A C    1 ? 
ATOM   3154 O O    . ASP A 1 234 ? -7.567  8.4     -1.13   1     31.313 ? 402 ASP A O    1 ? 
ATOM   3155 C CB   . ASP A 1 234 ? -5.957  10.638  -1.765  1     28.675 ? 402 ASP A CB   1 ? 
ATOM   3156 C CG   . ASP A 1 234 ? -5.366  10.089  -3.057  1     28.531 ? 402 ASP A CG   1 ? 
ATOM   3157 O OD1  . ASP A 1 234 ? -4.894  8.959   -3.055  1     28.454 ? 402 ASP A OD1  1 ? 
ATOM   3158 O OD2  . ASP A 1 234 ? -5.359  10.833  -4.053  1     38.684 ? 402 ASP A OD2  1 ? 
ATOM   3159 H H    . ASP A 1 234 ? -3.827  9.107   -0.908  1     24.282 ? 402 ASP A H    1 c 
ATOM   3160 H HA   . ASP A 1 234 ? -6.12   10.258  0.223   1     26.789 ? 402 ASP A HA   1 c 
ATOM   3161 H HB2  . ASP A 1 234 ? -6.918  10.778  -1.898  1     28.248 ? 402 ASP A HB2  1 c 
ATOM   3162 H HB3  . ASP A 1 234 ? -5.551  11.514  -1.598  1     28.232 ? 402 ASP A HB3  1 c 
ATOM   3163 N N    . GLU A 1 235 ? -5.859  7.362   -0.108  1     30.195 ? 403 GLU A N    1 ? 
ATOM   3164 C CA   . GLU A 1 235 ? -6.473  6.044   -0.142  1     33.114 ? 403 GLU A CA   1 ? 
ATOM   3165 C C    . GLU A 1 235 ? -7.214  5.787   1.171   1     33.56  ? 403 GLU A C    1 ? 
ATOM   3166 O O    . GLU A 1 235 ? -7.136  6.576   2.118   1     28.37  ? 403 GLU A O    1 ? 
ATOM   3167 C CB   . GLU A 1 235 ? -5.414  4.977   -0.407  1     37.806 ? 403 GLU A CB   1 ? 
ATOM   3168 C CG   . GLU A 1 235 ? -4.814  5.032   -1.812  1     45.734 ? 403 GLU A CG   1 ? 
ATOM   3169 C CD   . GLU A 1 235 ? -3.606  5.941   -2.035  1     55.655 ? 403 GLU A CD   1 ? 
ATOM   3170 O OE1  . GLU A 1 235 ? -3.177  6.716   -1.14   1     45.39  ? 403 GLU A OE1  1 ? 
ATOM   3171 O OE2  . GLU A 1 235 ? -3.088  5.866   -3.173  1     66.924 ? 403 GLU A OE2  1 ? 
ATOM   3172 H H    . GLU A 1 235 ? -5.048  7.452   0.304   1     30.412 ? 403 GLU A H    1 c 
ATOM   3173 H HA   . GLU A 1 235 ? -7.129  6.016   -0.884  1     33.44  ? 403 GLU A HA   1 c 
ATOM   3174 H HB2  . GLU A 1 235 ? -4.697  5.074   0.254   1     38.311 ? 403 GLU A HB2  1 c 
ATOM   3175 H HB3  . GLU A 1 235 ? -5.818  4.093   -0.278  1     38.188 ? 403 GLU A HB3  1 c 
ATOM   3176 H HG2  . GLU A 1 235 ? -4.555  4.122   -2.071  1     45.777 ? 403 GLU A HG2  1 c 
ATOM   3177 H HG3  . GLU A 1 235 ? -5.517  5.31    -2.437  1     45.634 ? 403 GLU A HG3  1 c 
ATOM   3178 N N    . GLY A 1 236 ? -8.011  4.717   1.182   1     29.2   ? 404 GLY A N    1 ? 
ATOM   3179 C CA   . GLY A 1 236 ? -8.751  4.326   2.369   1     32.791 ? 404 GLY A CA   1 ? 
ATOM   3180 C C    . GLY A 1 236 ? -7.801  4.086   3.544   1     28.74  ? 404 GLY A C    1 ? 
ATOM   3181 O O    . GLY A 1 236 ? -8.09   4.471   4.674   1     27.228 ? 404 GLY A O    1 ? 
ATOM   3182 H H    . GLY A 1 236 ? -8.099  4.214   0.424   1     31.048 ? 404 GLY A H    1 c 
ATOM   3183 H HA2  . GLY A 1 236 ? -9.393  5.037   2.601   1     30.978 ? 404 GLY A HA2  1 c 
ATOM   3184 H HA3  . GLY A 1 236 ? -9.259  3.502   2.179   1     30.978 ? 404 GLY A HA3  1 c 
ATOM   3185 N N    . TRP A 1 237 ? -6.658  3.471   3.27    1     25.954 ? 405 TRP A N    1 ? 
ATOM   3186 C CA   . TRP A 1 237 ? -5.72   3.176   4.338   1     27.806 ? 405 TRP A CA   1 ? 
ATOM   3187 C C    . TRP A 1 237 ? -5.213  4.466   4.98    1     24.288 ? 405 TRP A C    1 ? 
ATOM   3188 O O    . TRP A 1 237 ? -4.945  4.487   6.181   1     23.928 ? 405 TRP A O    1 ? 
ATOM   3189 C CB   . TRP A 1 237 ? -4.586  2.271   3.847   1     30.221 ? 405 TRP A CB   1 ? 
ATOM   3190 C CG   . TRP A 1 237 ? -3.621  2.843   2.849   1     38.377 ? 405 TRP A CG   1 ? 
ATOM   3191 C CD1  . TRP A 1 237 ? -3.639  2.669   1.496   1     44.777 ? 405 TRP A CD1  1 ? 
ATOM   3192 C CD2  . TRP A 1 237 ? -2.401  3.554   3.148   1     39.384 ? 405 TRP A CD2  1 ? 
ATOM   3193 N NE1  . TRP A 1 237 ? -2.549  3.271   0.924   1     43.832 ? 405 TRP A NE1  1 ? 
ATOM   3194 C CE2  . TRP A 1 237 ? -1.768  3.814   1.906   1     41.106 ? 405 TRP A CE2  1 ? 
ATOM   3195 C CE3  . TRP A 1 237 ? -1.799  4.012   4.327   1     38.781 ? 405 TRP A CE3  1 ? 
ATOM   3196 C CZ2  . TRP A 1 237 ? -0.564  4.513   1.817   1     40.889 ? 405 TRP A CZ2  1 ? 
ATOM   3197 C CZ3  . TRP A 1 237 ? -0.597  4.685   4.239   1     41.858 ? 405 TRP A CZ3  1 ? 
ATOM   3198 C CH2  . TRP A 1 237 ? 0.013   4.925   3       1     43.668 ? 405 TRP A CH2  1 ? 
ATOM   3199 H H    . TRP A 1 237 ? -6.459  3.217   2.415   1     27.127 ? 405 TRP A H    1 c 
ATOM   3200 H HA   . TRP A 1 237 ? -6.216  2.669   5.037   1     27.183 ? 405 TRP A HA   1 c 
ATOM   3201 H HB2  . TRP A 1 237 ? -4.077  1.972   4.631   1     31.354 ? 405 TRP A HB2  1 c 
ATOM   3202 H HB3  . TRP A 1 237 ? -4.988  1.465   3.46    1     31.354 ? 405 TRP A HB3  1 c 
ATOM   3203 H HD1  . TRP A 1 237 ? -4.313  2.227   1.01    1     42.844 ? 405 TRP A HD1  1 c 
ATOM   3204 H HE1  . TRP A 1 237 ? -2.38   3.299   0.068   1     43.288 ? 405 TRP A HE1  1 c 
ATOM   3205 H HE3  . TRP A 1 237 ? -2.201  3.851   5.164   1     39.668 ? 405 TRP A HE3  1 c 
ATOM   3206 H HZ2  . TRP A 1 237 ? -0.146  4.664   0.986   1     41.558 ? 405 TRP A HZ2  1 c 
ATOM   3207 H HZ3  . TRP A 1 237 ? -0.181  4.997   5.027   1     41.497 ? 405 TRP A HZ3  1 c 
ATOM   3208 H HH2  . TRP A 1 237 ? 0.827   5.395   2.973   1     42.521 ? 405 TRP A HH2  1 c 
ATOM   3209 N N    . CYS A 1 238 ? -5.145  5.546   4.181   1     22.662 ? 406 CYS A N    1 ? 
ATOM   3210 C CA   . CYS A 1 238 ? -4.699  6.846   4.649   1     20.798 ? 406 CYS A CA   1 ? 
ATOM   3211 C C    . CYS A 1 238 ? -5.709  7.412   5.633   1     19.331 ? 406 CYS A C    1 ? 
ATOM   3212 O O    . CYS A 1 238 ? -5.358  7.947   6.683   1     19.839 ? 406 CYS A O    1 ? 
ATOM   3213 C CB   . CYS A 1 238 ? -4.511  7.793   3.466   1     22.305 ? 406 CYS A CB   1 ? 
ATOM   3214 S SG   . CYS A 1 238 ? -3.286  7.231   2.253   1     22.642 ? 406 CYS A SG   1 ? 
ATOM   3215 H H    . CYS A 1 238 ? -5.353  5.457   3.296   1     22.724 ? 406 CYS A H    1 c 
ATOM   3216 H HA   . CYS A 1 238 ? -3.833  6.727   5.115   1     21.146 ? 406 CYS A HA   1 c 
ATOM   3217 H HB2  . CYS A 1 238 ? -5.371  7.915   3.009   1     22.041 ? 406 CYS A HB2  1 c 
ATOM   3218 H HB3  . CYS A 1 238 ? -4.226  8.669   3.805   1     22.024 ? 406 CYS A HB3  1 c 
ATOM   3219 N N    . GLU A 1 239 ? -6.991  7.34    5.272   1     19.687 ? 407 GLU A N    1 ? 
ATOM   3220 C CA   . GLU A 1 239 ? -8.033  7.869   6.105   1     20.87  ? 407 GLU A CA   1 ? 
ATOM   3221 C C    . GLU A 1 239 ? -8.093  7.11    7.435   1     19.413 ? 407 GLU A C    1 ? 
ATOM   3222 O O    . GLU A 1 239 ? -8.275  7.743   8.462   1     20.851 ? 407 GLU A O    1 ? 
ATOM   3223 C CB   . GLU A 1 239 ? -9.384  7.749   5.403   1     25.433 ? 407 GLU A CB   1 ? 
ATOM   3224 C CG   . GLU A 1 239 ? -10.512 8.268   6.288   1     32.948 ? 407 GLU A CG   1 ? 
ATOM   3225 C CD   . GLU A 1 239 ? -11.548 9.153   5.622   1     52.17  ? 407 GLU A CD   1 ? 
ATOM   3226 O OE1  . GLU A 1 239 ? -11.983 8.787   4.496   1     61.362 ? 407 GLU A OE1  1 ? 
ATOM   3227 O OE2  . GLU A 1 239 ? -11.903 10.198  6.246   1     60.503 ? 407 GLU A OE2  1 ? 
ATOM   3228 H H    . GLU A 1 239 ? -7.217  6.957   4.473   1     19.923 ? 407 GLU A H    1 c 
ATOM   3229 H HA   . GLU A 1 239 ? -7.84   8.824   6.285   1     21.094 ? 407 GLU A HA   1 c 
ATOM   3230 H HB2  . GLU A 1 239 ? -9.353  8.256   4.564   1     26.015 ? 407 GLU A HB2  1 c 
ATOM   3231 H HB3  . GLU A 1 239 ? -9.546  6.808   5.18    1     25.83  ? 407 GLU A HB3  1 c 
ATOM   3232 H HG2  . GLU A 1 239 ? -10.978 7.5     6.682   1     34.56  ? 407 GLU A HG2  1 c 
ATOM   3233 H HG3  . GLU A 1 239 ? -10.125 8.778   7.03    1     34.434 ? 407 GLU A HG3  1 c 
ATOM   3234 N N    . GLU A 1 240 ? -7.955  5.782   7.401   1     20.173 ? 408 GLU A N    1 ? 
ATOM   3235 C CA   . GLU A 1 240 ? -7.947  4.967   8.61    1     22.214 ? 408 GLU A CA   1 ? 
ATOM   3236 C C    . GLU A 1 240 ? -6.791  5.372   9.516   1     20.415 ? 408 GLU A C    1 ? 
ATOM   3237 O O    . GLU A 1 240 ? -6.986  5.439   10.737  1     18.702 ? 408 GLU A O    1 ? 
ATOM   3238 C CB   . GLU A 1 240 ? -7.837  3.484   8.243   1     26.839 ? 408 GLU A CB   1 ? 
ATOM   3239 C CG   . GLU A 1 240 ? -7.741  2.537   9.436   1     36.45  ? 408 GLU A CG   1 ? 
ATOM   3240 C CD   . GLU A 1 240 ? -7.253  1.132   9.067   1     52.796 ? 408 GLU A CD   1 ? 
ATOM   3241 O OE1  . GLU A 1 240 ? -7.028  0.842   7.864   1     54.479 ? 408 GLU A OE1  1 ? 
ATOM   3242 O OE2  . GLU A 1 240 ? -7.058  0.329   10.01   1     64.136 ? 408 GLU A OE2  1 ? 
ATOM   3243 H H    . GLU A 1 240 ? -7.873  5.364   6.593   1     20.465 ? 408 GLU A H    1 c 
ATOM   3244 H HA   . GLU A 1 240 ? -8.799  5.117   9.093   1     22.196 ? 408 GLU A HA   1 c 
ATOM   3245 H HB2  . GLU A 1 240 ? -8.62   3.235   7.709   1     27.622 ? 408 GLU A HB2  1 c 
ATOM   3246 H HB3  . GLU A 1 240 ? -7.044  3.367   7.679   1     27.787 ? 408 GLU A HB3  1 c 
ATOM   3247 H HG2  . GLU A 1 240 ? -7.128  2.908   10.1    1     36.336 ? 408 GLU A HG2  1 c 
ATOM   3248 H HG3  . GLU A 1 240 ? -8.625  2.46    9.855   1     36.878 ? 408 GLU A HG3  1 c 
ATOM   3249 N N    . ASN A 1 241 ? -5.611  5.662   8.92    1     18.979 ? 409 ASN A N    1 ? 
ATOM   3250 C CA   . ASN A 1 241 ? -4.468  6.117   9.696   1     19.568 ? 409 ASN A CA   1 ? 
ATOM   3251 C C    . ASN A 1 241 ? -4.795  7.442   10.392  1     20.125 ? 409 ASN A C    1 ? 
ATOM   3252 O O    . ASN A 1 241 ? -4.472  7.656   11.561  1     16.752 ? 409 ASN A O    1 ? 
ATOM   3253 C CB   . ASN A 1 241 ? -3.207  6.241   8.847   1     22.055 ? 409 ASN A CB   1 ? 
ATOM   3254 C CG   . ASN A 1 241 ? -2.531  4.919   8.602   1     24.863 ? 409 ASN A CG   1 ? 
ATOM   3255 O OD1  . ASN A 1 241 ? -2.842  3.9     9.232   1     24.836 ? 409 ASN A OD1  1 ? 
ATOM   3256 N ND2  . ASN A 1 241 ? -1.553  4.93    7.714   1     24.943 ? 409 ASN A ND2  1 ? 
ATOM   3257 H H    . ASN A 1 241 ? -5.519  5.558   8.017   1     19.502 ? 409 ASN A H    1 c 
ATOM   3258 H HA   . ASN A 1 241 ? -4.292  5.45    10.396  1     20.034 ? 409 ASN A HA   1 c 
ATOM   3259 H HB2  . ASN A 1 241 ? -3.439  6.641   7.986   1     22.038 ? 409 ASN A HB2  1 c 
ATOM   3260 H HB3  . ASN A 1 241 ? -2.577  6.84    9.294   1     22.061 ? 409 ASN A HB3  1 c 
ATOM   3261 H HD21 . ASN A 1 241 ? -1.207  4.164   7.429   1     24.912 ? 409 ASN A HD21 1 c 
ATOM   3262 H HD22 . ASN A 1 241 ? -1.239  5.7     7.402   1     24.896 ? 409 ASN A HD22 1 c 
ATOM   3263 N N    . ARG A 1 242 ? -5.454  8.363   9.676   1     17.151 ? 410 ARG A N    1 ? 
ATOM   3264 C CA   . ARG A 1 242 ? -5.764  9.672   10.23   1     17.67  ? 410 ARG A CA   1 ? 
ATOM   3265 C C    . ARG A 1 242 ? -6.799  9.555   11.343  1     16.892 ? 410 ARG A C    1 ? 
ATOM   3266 O O    . ARG A 1 242 ? -6.744  10.346  12.307  1     17.396 ? 410 ARG A O    1 ? 
ATOM   3267 C CB   . ARG A 1 242 ? -6.232  10.63   9.117   1     19.111 ? 410 ARG A CB   1 ? 
ATOM   3268 C CG   . ARG A 1 242 ? -5.122  11.1    8.195   1     19.123 ? 410 ARG A CG   1 ? 
ATOM   3269 C CD   . ARG A 1 242 ? -5.515  12.172  7.167   1     19.355 ? 410 ARG A CD   1 ? 
ATOM   3270 N NE   . ARG A 1 242 ? -6.614  11.783  6.279   1     22.367 ? 410 ARG A NE   1 ? 
ATOM   3271 C CZ   . ARG A 1 242 ? -6.486  11.26   5.079   1     24.042 ? 410 ARG A CZ   1 ? 
ATOM   3272 N NH1  . ARG A 1 242 ? -5.296  11.028  4.58    1     21.386 ? 410 ARG A NH1  1 ? 
ATOM   3273 N NH2  . ARG A 1 242 ? -7.56   10.957  4.369   1     24.841 ? 410 ARG A NH2  1 ? 
ATOM   3274 H H    . ARG A 1 242 ? -5.708  8.175   8.819   1     17.969 ? 410 ARG A H    1 c 
ATOM   3275 H HA   . ARG A 1 242 ? -4.933  10.047  10.618  1     17.688 ? 410 ARG A HA   1 c 
ATOM   3276 H HB2  . ARG A 1 242 ? -6.918  10.178  8.581   1     18.772 ? 410 ARG A HB2  1 c 
ATOM   3277 H HB3  . ARG A 1 242 ? -6.649  11.415  9.533   1     18.767 ? 410 ARG A HB3  1 c 
ATOM   3278 H HG2  . ARG A 1 242 ? -4.391  11.454  8.746   1     19.162 ? 410 ARG A HG2  1 c 
ATOM   3279 H HG3  . ARG A 1 242 ? -4.765  10.324  7.713   1     19.174 ? 410 ARG A HG3  1 c 
ATOM   3280 H HD2  . ARG A 1 242 ? -5.777  12.979  7.656   1     19.973 ? 410 ARG A HD2  1 c 
ATOM   3281 H HD3  . ARG A 1 242 ? -4.73   12.4    6.631   1     19.99  ? 410 ARG A HD3  1 c 
ATOM   3282 H HE   . ARG A 1 242 ? -7.425  11.909  6.574   1     22.037 ? 410 ARG A HE   1 c 
ATOM   3283 H HH11 . ARG A 1 242 ? -4.708  10.555  5.042   1     22.152 ? 410 ARG A HH11 1 c 
ATOM   3284 H HH12 . ARG A 1 242 ? -5.085  11.347  3.783   1     22.167 ? 410 ARG A HH12 1 c 
ATOM   3285 H HH21 . ARG A 1 242 ? -8.315  11.402  4.495   1     24.546 ? 410 ARG A HH21 1 c 
ATOM   3286 H HH22 . ARG A 1 242 ? -7.518  10.309  3.767   1     24.557 ? 410 ARG A HH22 1 c 
ATOM   3287 N N    . THR A 1 243 ? -7.797  8.677   11.19   1     17.159 ? 411 THR A N    1 ? 
ATOM   3288 C CA   . THR A 1 243 ? -8.826  8.583   12.227  1     18.185 ? 411 THR A CA   1 ? 
ATOM   3289 C C    . THR A 1 243 ? -8.286  7.821   13.434  1     18.191 ? 411 THR A C    1 ? 
ATOM   3290 O O    . THR A 1 243 ? -8.678  8.11    14.562  1     19.663 ? 411 THR A O    1 ? 
ATOM   3291 C CB   . THR A 1 243 ? -10.145 8.007   11.709  1     21.824 ? 411 THR A CB   1 ? 
ATOM   3292 O OG1  . THR A 1 243 ? -9.941  6.724   11.162  1     27.758 ? 411 THR A OG1  1 ? 
ATOM   3293 C CG2  . THR A 1 243 ? -10.661 8.829   10.537  1     20.887 ? 411 THR A CG2  1 ? 
ATOM   3294 H H    . THR A 1 243 ? -7.85   8.145   10.449  1     17.361 ? 411 THR A H    1 c 
ATOM   3295 H HA   . THR A 1 243 ? -9.021  9.498   12.526  1     18.589 ? 411 THR A HA   1 c 
ATOM   3296 H HB   . THR A 1 243 ? -10.819 7.965   12.428  1     21.976 ? 411 THR A HB   1 c 
ATOM   3297 H HG21 . THR A 1 243 ? -11.538 8.502   10.273  1     21.155 ? 411 THR A HG21 1 c 
ATOM   3298 H HG22 . THR A 1 243 ? -10.052 8.753   9.787   1     21.141 ? 411 THR A HG22 1 c 
ATOM   3299 H HG23 . THR A 1 243 ? -10.731 9.762   10.801  1     21.155 ? 411 THR A HG23 1 c 
ATOM   3300 N N    . ASN A 1 244 ? -7.349  6.911   13.23   1     17.352 ? 412 ASN A N    1 ? 
ATOM   3301 C CA   . ASN A 1 244 ? -6.732  6.238   14.371  1     17.013 ? 412 ASN A CA   1 ? 
ATOM   3302 C C    . ASN A 1 244 ? -5.809  7.198   15.124  1     17.308 ? 412 ASN A C    1 ? 
ATOM   3303 O O    . ASN A 1 244 ? -5.761  7.177   16.358  1     17.613 ? 412 ASN A O    1 ? 
ATOM   3304 C CB   . ASN A 1 244 ? -6.08   4.921   13.979  1     17.259 ? 412 ASN A CB   1 ? 
ATOM   3305 C CG   . ASN A 1 244 ? -7.1    3.85    13.712  1     17.792 ? 412 ASN A CG   1 ? 
ATOM   3306 O OD1  . ASN A 1 244 ? -8.135  3.794   14.377  1     21.572 ? 412 ASN A OD1  1 ? 
ATOM   3307 N ND2  . ASN A 1 244 ? -6.816  2.951   12.771  1     18.995 ? 412 ASN A ND2  1 ? 
ATOM   3308 H H    . ASN A 1 244 ? -7.093  6.683   12.383  1     17.472 ? 412 ASN A H    1 c 
ATOM   3309 H HA   . ASN A 1 244 ? -7.453  6.011   14.996  1     17.228 ? 412 ASN A HA   1 c 
ATOM   3310 H HB2  . ASN A 1 244 ? -5.535  5.056   13.179  1     17.342 ? 412 ASN A HB2  1 c 
ATOM   3311 H HB3  . ASN A 1 244 ? -5.493  4.627   14.703  1     17.326 ? 412 ASN A HB3  1 c 
ATOM   3312 H HD21 . ASN A 1 244 ? -7.469  2.474   12.407  1     18.739 ? 412 ASN A HD21 1 c 
ATOM   3313 H HD22 . ASN A 1 244 ? -5.977  2.827   12.511  1     18.626 ? 412 ASN A HD22 1 c 
ATOM   3314 N N    . ALA A 1 245 ? -5.112  8.083   14.382  1     17.202 ? 413 ALA A N    1 ? 
ATOM   3315 C CA   . ALA A 1 245 ? -4.356  9.154   15.004  1     17.789 ? 413 ALA A CA   1 ? 
ATOM   3316 C C    . ALA A 1 245 ? -5.263  10.069  15.808  1     17.435 ? 413 ALA A C    1 ? 
ATOM   3317 O O    . ALA A 1 245 ? -4.852  10.544  16.873  1     18.854 ? 413 ALA A O    1 ? 
ATOM   3318 C CB   . ALA A 1 245 ? -3.54   9.934   13.983  1     17.755 ? 413 ALA A CB   1 ? 
ATOM   3319 H H    . ALA A 1 245 ? -5.098  8.003   13.472  1     17.358 ? 413 ALA A H    1 c 
ATOM   3320 H HA   . ALA A 1 245 ? -3.72   8.731   15.645  1     17.607 ? 413 ALA A HA   1 c 
ATOM   3321 H HB1  . ALA A 1 245 ? -2.914  9.337   13.54   1     17.765 ? 413 ALA A HB1  1 c 
ATOM   3322 H HB2  . ALA A 1 245 ? -4.133  10.326  13.321  1     17.765 ? 413 ALA A HB2  1 c 
ATOM   3323 H HB3  . ALA A 1 245 ? -3.047  10.641  14.431  1     17.765 ? 413 ALA A HB3  1 c 
ATOM   3324 N N    . ALA A 1 246 ? -6.449  10.39   15.269  1     16.789 ? 414 ALA A N    1 ? 
ATOM   3325 C CA   . ALA A 1 246 ? -7.43   11.183  15.98   1     17.105 ? 414 ALA A CA   1 ? 
ATOM   3326 C C    . ALA A 1 246 ? -7.849  10.5    17.29   1     16.31  ? 414 ALA A C    1 ? 
ATOM   3327 O O    . ALA A 1 246 ? -7.951  11.178  18.32   1     16.931 ? 414 ALA A O    1 ? 
ATOM   3328 C CB   . ALA A 1 246 ? -8.648  11.481  15.106  1     19.283 ? 414 ALA A CB   1 ? 
ATOM   3329 H H    . ALA A 1 246 ? -6.645  10.112  14.421  1     17.033 ? 414 ALA A H    1 c 
ATOM   3330 H HA   . ALA A 1 246 ? -6.998  12.049  16.219  1     17.274 ? 414 ALA A HA   1 c 
ATOM   3331 H HB1  . ALA A 1 246 ? -8.361  11.902  14.278  1     18.633 ? 414 ALA A HB1  1 c 
ATOM   3332 H HB2  . ALA A 1 246 ? -9.114  10.654  14.9    1     18.638 ? 414 ALA A HB2  1 c 
ATOM   3333 H HB3  . ALA A 1 246 ? -9.251  12.079  15.578  1     18.683 ? 414 ALA A HB3  1 c 
ATOM   3334 N N    . ARG A 1 247 ? -7.975  9.191   17.277  1     16.808 ? 415 ARG A N    1 ? 
ATOM   3335 C CA   . ARG A 1 247 ? -8.256  8.442   18.502  1     19.116 ? 415 ARG A CA   1 ? 
ATOM   3336 C C    . ARG A 1 247 ? -7.164  8.628   19.554  1     20.172 ? 415 ARG A C    1 ? 
ATOM   3337 O O    . ARG A 1 247 ? -7.454  8.857   20.744  1     19.947 ? 415 ARG A O    1 ? 
ATOM   3338 C CB   . ARG A 1 247 ? -8.45   6.968   18.151  1     19.454 ? 415 ARG A CB   1 ? 
ATOM   3339 C CG   . ARG A 1 247 ? -9.799  6.711   17.488  1     18.347 ? 415 ARG A CG   1 ? 
ATOM   3340 C CD   . ARG A 1 247 ? -9.854  5.315   16.881  1     17.032 ? 415 ARG A CD   1 ? 
ATOM   3341 N NE   . ARG A 1 247 ? -9.915  4.29    17.937  1     17.492 ? 415 ARG A NE   1 ? 
ATOM   3342 C CZ   . ARG A 1 247 ? -9.854  3.003   17.734  1     17.408 ? 415 ARG A CZ   1 ? 
ATOM   3343 N NH1  . ARG A 1 247 ? -9.57   2.541   16.52   1     19.828 ? 415 ARG A NH1  1 ? 
ATOM   3344 N NH2  . ARG A 1 247 ? -10.004 2.145   18.736  1     18.19  ? 415 ARG A NH2  1 ? 
ATOM   3345 H H    . ARG A 1 247 ? -7.904  8.737   16.487  1     17.202 ? 415 ARG A H    1 c 
ATOM   3346 H HA   . ARG A 1 247 ? -9.107  8.783   18.878  1     18.875 ? 415 ARG A HA   1 c 
ATOM   3347 H HB2  . ARG A 1 247 ? -7.736  6.676   17.55   1     19.085 ? 415 ARG A HB2  1 c 
ATOM   3348 H HB3  . ARG A 1 247 ? -8.392  6.432   18.971  1     19.119 ? 415 ARG A HB3  1 c 
ATOM   3349 H HG2  . ARG A 1 247 ? -10.514 6.802   18.155  1     18.274 ? 415 ARG A HG2  1 c 
ATOM   3350 H HG3  . ARG A 1 247 ? -9.949  7.377   16.782  1     18.278 ? 415 ARG A HG3  1 c 
ATOM   3351 H HD2  . ARG A 1 247 ? -10.642 5.239   16.31   1     17.436 ? 415 ARG A HD2  1 c 
ATOM   3352 H HD3  . ARG A 1 247 ? -9.062  5.167   16.332  1     17.469 ? 415 ARG A HD3  1 c 
ATOM   3353 H HE   . ARG A 1 247 ? -9.998  4.56    18.762  1     17.388 ? 415 ARG A HE   1 c 
ATOM   3354 H HH11 . ARG A 1 247 ? -10.167 2.615   15.872  1     19.037 ? 415 ARG A HH11 1 c 
ATOM   3355 H HH12 . ARG A 1 247 ? -8.786  2.163   16.367  1     19.046 ? 415 ARG A HH12 1 c 
ATOM   3356 H HH21 . ARG A 1 247 ? -9.629  2.314   19.518  1     17.941 ? 415 ARG A HH21 1 c 
ATOM   3357 H HH22 . ARG A 1 247 ? -10.479 1.41    18.616  1     17.945 ? 415 ARG A HH22 1 c 
ATOM   3358 N N    . VAL A 1 248 ? -5.894  8.585   19.103  1     18.265 ? 416 VAL A N    1 ? 
ATOM   3359 C CA   . VAL A 1 248 ? -4.788  8.724   20.029  1     17.588 ? 416 VAL A CA   1 ? 
ATOM   3360 C C    . VAL A 1 248 ? -4.749  10.132  20.584  1     17.672 ? 416 VAL A C    1 ? 
ATOM   3361 O O    . VAL A 1 248 ? -4.591  10.3    21.785  1     17.114 ? 416 VAL A O    1 ? 
ATOM   3362 C CB   . VAL A 1 248 ? -3.483  8.301   19.33   1     17.157 ? 416 VAL A CB   1 ? 
ATOM   3363 C CG1  . VAL A 1 248 ? -2.253  8.685   20.124  1     18.88  ? 416 VAL A CG1  1 ? 
ATOM   3364 C CG2  . VAL A 1 248 ? -3.505  6.82    19.019  1     16.182 ? 416 VAL A CG2  1 ? 
ATOM   3365 H H    . VAL A 1 248 ? -5.723  8.46    18.214  1     18.483 ? 416 VAL A H    1 c 
ATOM   3366 H HA   . VAL A 1 248 ? -4.94   8.109   20.774  1     17.663 ? 416 VAL A HA   1 c 
ATOM   3367 H HB   . VAL A 1 248 ? -3.444  8.786   18.472  1     17.365 ? 416 VAL A HB   1 c 
ATOM   3368 H HG11 . VAL A 1 248 ? -2.412  8.52    21.069  1     18.344 ? 416 VAL A HG11 1 c 
ATOM   3369 H HG12 . VAL A 1 248 ? -2.058  9.627   19.988  1     18.344 ? 416 VAL A HG12 1 c 
ATOM   3370 H HG13 . VAL A 1 248 ? -1.494  8.155   19.828  1     18.324 ? 416 VAL A HG13 1 c 
ATOM   3371 H HG21 . VAL A 1 248 ? -2.644  6.548   18.662  1     16.501 ? 416 VAL A HG21 1 c 
ATOM   3372 H HG22 . VAL A 1 248 ? -4.198  6.634   18.365  1     16.502 ? 416 VAL A HG22 1 c 
ATOM   3373 H HG23 . VAL A 1 248 ? -3.688  6.321   19.833  1     16.489 ? 416 VAL A HG23 1 c 
ATOM   3374 N N    . ARG A 1 249 ? -4.979  11.141  19.72   1     16.12  ? 417 ARG A N    1 ? 
ATOM   3375 C CA   . ARG A 1 249 ? -5.009  12.522  20.137  1     16.979 ? 417 ARG A CA   1 ? 
ATOM   3376 C C    . ARG A 1 249 ? -6.142  12.784  21.13   1     16.391 ? 417 ARG A C    1 ? 
ATOM   3377 O O    . ARG A 1 249 ? -5.975  13.526  22.092  1     17.322 ? 417 ARG A O    1 ? 
ATOM   3378 C CB   . ARG A 1 249 ? -5.035  13.451  18.89   1     17.398 ? 417 ARG A CB   1 ? 
ATOM   3379 C CG   . ARG A 1 249 ? -5.107  14.93   19.246  1     18.71  ? 417 ARG A CG   1 ? 
ATOM   3380 C CD   . ARG A 1 249 ? -3.879  15.371  19.996  1     22.517 ? 417 ARG A CD   1 ? 
ATOM   3381 N NE   . ARG A 1 249 ? -3.943  16.761  20.432  1     28.318 ? 417 ARG A NE   1 ? 
ATOM   3382 C CZ   . ARG A 1 249 ? -4.559  17.211  21.532  1     35.596 ? 417 ARG A CZ   1 ? 
ATOM   3383 N NH1  . ARG A 1 249 ? -5.165  16.389  22.367  1     37.552 ? 417 ARG A NH1  1 ? 
ATOM   3384 N NH2  . ARG A 1 249 ? -4.508  18.49   21.851  1     32.47  ? 417 ARG A NH2  1 ? 
ATOM   3385 H H    . ARG A 1 249 ? -5.109  10.95   18.835  1     16.693 ? 417 ARG A H    1 c 
ATOM   3386 H HA   . ARG A 1 249 ? -4.158  12.694  20.611  1     16.841 ? 417 ARG A HA   1 c 
ATOM   3387 H HB2  . ARG A 1 249 ? -4.227  13.291  18.357  1     17.594 ? 417 ARG A HB2  1 c 
ATOM   3388 H HB3  . ARG A 1 249 ? -5.811  13.219  18.336  1     17.594 ? 417 ARG A HB3  1 c 
ATOM   3389 H HG2  . ARG A 1 249 ? -5.186  15.458  18.422  1     19.207 ? 417 ARG A HG2  1 c 
ATOM   3390 H HG3  . ARG A 1 249 ? -5.902  15.103  19.795  1     19.195 ? 417 ARG A HG3  1 c 
ATOM   3391 H HD2  . ARG A 1 249 ? -3.747  14.803  20.779  1     22.774 ? 417 ARG A HD2  1 c 
ATOM   3392 H HD3  . ARG A 1 249 ? -3.1    15.255  19.414  1     22.769 ? 417 ARG A HD3  1 c 
ATOM   3393 H HE   . ARG A 1 249 ? -3.546  17.354  19.932  1     28.395 ? 417 ARG A HE   1 c 
ATOM   3394 H HH11 . ARG A 1 249 ? -5.83   15.883  22.079  1     36.939 ? 417 ARG A HH11 1 c 
ATOM   3395 H HH12 . ARG A 1 249 ? -4.903  16.348  23.21   1     36.939 ? 417 ARG A HH12 1 c 
ATOM   3396 H HH21 . ARG A 1 249 ? -3.771  18.952  21.698  1     33.366 ? 417 ARG A HH21 1 c 
ATOM   3397 H HH22 . ARG A 1 249 ? -5.213  18.879  22.216  1     33.421 ? 417 ARG A HH22 1 c 
ATOM   3398 N N    . ALA A 1 250 ? -7.301  12.153  20.94   1     18.915 ? 418 ALA A N    1 ? 
ATOM   3399 C CA   . ALA A 1 250 ? -8.452  12.322  21.832  1     18.641 ? 418 ALA A CA   1 ? 
ATOM   3400 C C    . ALA A 1 250 ? -8.145  11.79   23.23   1     19.693 ? 418 ALA A C    1 ? 
ATOM   3401 O O    . ALA A 1 250 ? -8.806  12.191  24.187  1     19.67  ? 418 ALA A O    1 ? 
ATOM   3402 C CB   . ALA A 1 250 ? -9.692  11.642  21.244  1     16.894 ? 418 ALA A CB   1 ? 
ATOM   3403 H H    . ALA A 1 250 ? -7.39   11.599  20.219  1     18.186 ? 418 ALA A H    1 c 
ATOM   3404 H HA   . ALA A 1 250 ? -8.634  13.299  21.912  1     18.542 ? 418 ALA A HA   1 c 
ATOM   3405 H HB1  . ALA A 1 250 ? -9.908  12.042  20.385  1     17.388 ? 418 ALA A HB1  1 c 
ATOM   3406 H HB2  . ALA A 1 250 ? -9.517  10.693  21.121  1     17.388 ? 418 ALA A HB2  1 c 
ATOM   3407 H HB3  . ALA A 1 250 ? -10.444 11.754  21.849  1     17.388 ? 418 ALA A HB3  1 c 
ATOM   3408 N N    . ALA A 1 251 ? -7.129  10.932  23.349  1     17.7   ? 419 ALA A N    1 ? 
ATOM   3409 C CA   . ALA A 1 251 ? -6.75   10.373  24.641  1     20.138 ? 419 ALA A CA   1 ? 
ATOM   3410 C C    . ALA A 1 251 ? -5.614  11.183  25.27   1     18.174 ? 419 ALA A C    1 ? 
ATOM   3411 O O    . ALA A 1 251 ? -5.037  10.773  26.264  1     20.355 ? 419 ALA A O    1 ? 
ATOM   3412 C CB   . ALA A 1 251 ? -6.361  8.933   24.475  1     18.983 ? 419 ALA A CB   1 ? 
ATOM   3413 H H    . ALA A 1 251 ? -6.682  10.647  22.606  1     18.675 ? 419 ALA A H    1 c 
ATOM   3414 H HA   . ALA A 1 251 ? -7.535  10.422  25.249  1     19.074 ? 419 ALA A HA   1 c 
ATOM   3415 H HB1  . ALA A 1 251 ? -7.06   8.459   23.994  1     19.322 ? 419 ALA A HB1  1 c 
ATOM   3416 H HB2  . ALA A 1 251 ? -5.53   8.873   23.974  1     19.322 ? 419 ALA A HB2  1 c 
ATOM   3417 H HB3  . ALA A 1 251 ? -6.239  8.524   25.349  1     19.326 ? 419 ALA A HB3  1 c 
ATOM   3418 N N    . GLY A 1 252 ? -5.305  12.334  24.696  1     18.006 ? 420 GLY A N    1 ? 
ATOM   3419 C CA   . GLY A 1 252 ? -4.413  13.311  25.29   1     19.767 ? 420 GLY A CA   1 ? 
ATOM   3420 C C    . GLY A 1 252 ? -2.939  13.048  24.984  1     19.162 ? 420 GLY A C    1 ? 
ATOM   3421 O O    . GLY A 1 252 ? -2.076  13.598  25.648  1     22.389 ? 420 GLY A O    1 ? 
ATOM   3422 H H    . GLY A 1 252 ? -5.649  12.526  23.873  1     18.435 ? 420 GLY A H    1 c 
ATOM   3423 H HA2  . GLY A 1 252 ? -4.656  14.205  24.954  1     19.197 ? 420 GLY A HA2  1 c 
ATOM   3424 H HA3  . GLY A 1 252 ? -4.546  13.316  26.268  1     19.198 ? 420 GLY A HA3  1 c 
ATOM   3425 N N    . LYS A 1 253 ? -2.646  12.192  24.003  1     18.341 ? 421 LYS A N    1 ? 
ATOM   3426 C CA   . LYS A 1 253 ? -1.279  11.896  23.604  1     18.17  ? 421 LYS A CA   1 ? 
ATOM   3427 C C    . LYS A 1 253 ? -0.802  12.887  22.548  1     17.105 ? 421 LYS A C    1 ? 
ATOM   3428 O O    . LYS A 1 253 ? -1.581  13.459  21.788  1     19.277 ? 421 LYS A O    1 ? 
ATOM   3429 C CB   . LYS A 1 253 ? -1.249  10.474  23.058  1     18.915 ? 421 LYS A CB   1 ? 
ATOM   3430 C CG   . LYS A 1 253 ? -1.914  9.412   23.933  1     18.75  ? 421 LYS A CG   1 ? 
ATOM   3431 C CD   . LYS A 1 253 ? -1.445  9.39    25.377  1     18.174 ? 421 LYS A CD   1 ? 
ATOM   3432 C CE   . LYS A 1 253 ? -2.111  8.281   26.173  1     18.3   ? 421 LYS A CE   1 ? 
ATOM   3433 N NZ   . LYS A 1 253 ? -1.534  8.08    27.521  1     18.951 ? 421 LYS A NZ   1 ? 
ATOM   3434 H H    . LYS A 1 253 ? -3.327  11.798  23.538  1     18.502 ? 421 LYS A H    1 c 
ATOM   3435 H HA   . LYS A 1 253 ? -0.692  11.953  24.4    1     18.134 ? 421 LYS A HA   1 c 
ATOM   3436 H HB2  . LYS A 1 253 ? -1.69   10.471  22.183  1     18.686 ? 421 LYS A HB2  1 c 
ATOM   3437 H HB3  . LYS A 1 253 ? -0.314  10.214  22.918  1     18.671 ? 421 LYS A HB3  1 c 
ATOM   3438 H HG2  . LYS A 1 253 ? -2.885  9.555   23.917  1     18.651 ? 421 LYS A HG2  1 c 
ATOM   3439 H HG3  . LYS A 1 253 ? -1.741  8.532   23.533  1     18.653 ? 421 LYS A HG3  1 c 
ATOM   3440 H HD2  . LYS A 1 253 ? -0.472  9.261   25.399  1     18.332 ? 421 LYS A HD2  1 c 
ATOM   3441 H HD3  . LYS A 1 253 ? -1.649  10.253  25.799  1     18.332 ? 421 LYS A HD3  1 c 
ATOM   3442 H HE2  . LYS A 1 253 ? -3.059  8.486   26.268  1     18.422 ? 421 LYS A HE2  1 c 
ATOM   3443 H HE3  . LYS A 1 253 ? -2.037  7.447   25.676  1     18.422 ? 421 LYS A HE3  1 c 
ATOM   3444 H HZ1  . LYS A 1 253 ? -1.619  8.84    28.007  1     18.748 ? 421 LYS A HZ1  1 c 
ATOM   3445 H HZ2  . LYS A 1 253 ? -0.656  7.868   27.45   1     18.748 ? 421 LYS A HZ2  1 c 
ATOM   3446 H HZ3  . LYS A 1 253 ? -1.969  7.407   27.943  1     18.748 ? 421 LYS A HZ3  1 c 
ATOM   3447 N N    . LEU A 1 254 ? 0.496   13.148  22.581  1     15.893 ? 422 LEU A N    1 ? 
ATOM   3448 C CA   . LEU A 1 254 ? 1.132   13.988  21.582  1     15.049 ? 422 LEU A CA   1 ? 
ATOM   3449 C C    . LEU A 1 254 ? 1.172   13.215  20.265  1     17.33  ? 422 LEU A C    1 ? 
ATOM   3450 O O    . LEU A 1 254 ? 1.785   12.169  20.22   1     20.827 ? 422 LEU A O    1 ? 
ATOM   3451 C CB   . LEU A 1 254 ? 2.549   14.274  22.065  1     15.308 ? 422 LEU A CB   1 ? 
ATOM   3452 C CG   . LEU A 1 254 ? 3.411   15.136  21.13   1     17.494 ? 422 LEU A CG   1 ? 
ATOM   3453 C CD1  . LEU A 1 254 ? 2.688   16.419  20.823  1     19.109 ? 422 LEU A CD1  1 ? 
ATOM   3454 C CD2  . LEU A 1 254 ? 4.717   15.4    21.784  1     20.091 ? 422 LEU A CD2  1 ? 
ATOM   3455 H H    . LEU A 1 254 ? 1.01    12.789  23.246  1     16.001 ? 422 LEU A H    1 c 
ATOM   3456 H HA   . LEU A 1 254 ? 0.621   14.83   21.483  1     15.699 ? 422 LEU A HA   1 c 
ATOM   3457 H HB2  . LEU A 1 254 ? 2.49    14.727  22.938  1     15.743 ? 422 LEU A HB2  1 c 
ATOM   3458 H HB3  . LEU A 1 254 ? 3.008   13.415  22.206  1     15.746 ? 422 LEU A HB3  1 c 
ATOM   3459 H HG   . LEU A 1 254 ? 3.568   14.64   20.286  1     17.818 ? 422 LEU A HG   1 c 
ATOM   3460 H HD11 . LEU A 1 254 ? 2.012   16.257  20.144  1     18.591 ? 422 LEU A HD11 1 c 
ATOM   3461 H HD12 . LEU A 1 254 ? 3.322   17.079  20.495  1     18.616 ? 422 LEU A HD12 1 c 
ATOM   3462 H HD13 . LEU A 1 254 ? 2.262   16.755  21.63   1     18.589 ? 422 LEU A HD13 1 c 
ATOM   3463 H HD21 . LEU A 1 254 ? 5.154   14.556  21.989  1     19.267 ? 422 LEU A HD21 1 c 
ATOM   3464 H HD22 . LEU A 1 254 ? 4.574   15.897  22.607  1     19.267 ? 422 LEU A HD22 1 c 
ATOM   3465 H HD23 . LEU A 1 254 ? 5.281   15.918  21.186  1     19.264 ? 422 LEU A HD23 1 c 
ATOM   3466 N N    . VAL A 1 255 ? 0.703   13.827  19.182  1     16.831 ? 423 VAL A N    1 ? 
ATOM   3467 C CA   . VAL A 1 255 ? 0.808   13.184  17.881  1     17.902 ? 423 VAL A CA   1 ? 
ATOM   3468 C C    . VAL A 1 255 ? 1.734   14.029  17.025  1     15.723 ? 423 VAL A C    1 ? 
ATOM   3469 O O    . VAL A 1 255 ? 1.432   15.186  16.768  1     16.934 ? 423 VAL A O    1 ? 
ATOM   3470 C CB   . VAL A 1 255 ? -0.548  12.977  17.17   1     18.252 ? 423 VAL A CB   1 ? 
ATOM   3471 C CG1  . VAL A 1 255 ? -0.356  12.442  15.752  1     17.939 ? 423 VAL A CG1  1 ? 
ATOM   3472 C CG2  . VAL A 1 255 ? -1.438  12.066  17.998  1     20.082 ? 423 VAL A CG2  1 ? 
ATOM   3473 H H    . VAL A 1 255 ? 0.313   14.651  19.245  1     17.157 ? 423 VAL A H    1 c 
ATOM   3474 H HA   . VAL A 1 255 ? 1.211   12.31   18.002  1     17.34  ? 423 VAL A HA   1 c 
ATOM   3475 H HB   . VAL A 1 255 ? -0.984  13.859  17.109  1     18.456 ? 423 VAL A HB   1 c 
ATOM   3476 H HG11 . VAL A 1 255 ? 0.403   11.834  15.732  1     18.021 ? 423 VAL A HG11 1 c 
ATOM   3477 H HG12 . VAL A 1 255 ? -0.194  13.182  15.143  1     18.021 ? 423 VAL A HG12 1 c 
ATOM   3478 H HG13 . VAL A 1 255 ? -1.156  11.966  15.472  1     18.046 ? 423 VAL A HG13 1 c 
ATOM   3479 H HG21 . VAL A 1 255 ? -2.281  11.925  17.535  1     19.508 ? 423 VAL A HG21 1 c 
ATOM   3480 H HG22 . VAL A 1 255 ? -1.61   12.477  18.862  1     19.505 ? 423 VAL A HG22 1 c 
ATOM   3481 H HG23 . VAL A 1 255 ? -0.995  11.211  18.13   1     19.517 ? 423 VAL A HG23 1 c 
ATOM   3482 N N    . LEU A 1 256 ? 2.85    13.416  16.61   1     17.378 ? 424 LEU A N    1 ? 
ATOM   3483 C CA   . LEU A 1 256 ? 3.859   14.053  15.781  1     16.666 ? 424 LEU A CA   1 ? 
ATOM   3484 C C    . LEU A 1 256 ? 3.69    13.495  14.372  1     18.207 ? 424 LEU A C    1 ? 
ATOM   3485 O O    . LEU A 1 256 ? 3.975   12.326  14.141  1     17.961 ? 424 LEU A O    1 ? 
ATOM   3486 C CB   . LEU A 1 256 ? 5.243   13.678  16.331  1     17.825 ? 424 LEU A CB   1 ? 
ATOM   3487 C CG   . LEU A 1 256 ? 5.553   14.052  17.784  1     18.874 ? 424 LEU A CG   1 ? 
ATOM   3488 C CD1  . LEU A 1 256 ? 6.934   13.533  18.308  1     21.451 ? 424 LEU A CD1  1 ? 
ATOM   3489 C CD2  . LEU A 1 256 ? 5.503   15.553  17.931  1     20.981 ? 424 LEU A CD2  1 ? 
ATOM   3490 H H    . LEU A 1 256 ? 2.99    12.548  16.857  1     16.827 ? 424 LEU A H    1 c 
ATOM   3491 H HA   . LEU A 1 256 ? 3.738   15.032  15.79   1     17.299 ? 424 LEU A HA   1 c 
ATOM   3492 H HB2  . LEU A 1 256 ? 5.355   12.704  16.239  1     17.79  ? 424 LEU A HB2  1 c 
ATOM   3493 H HB3  . LEU A 1 256 ? 5.923   14.097  15.755  1     17.792 ? 424 LEU A HB3  1 c 
ATOM   3494 H HG   . LEU A 1 256 ? 4.845   13.665  18.361  1     19.488 ? 424 LEU A HG   1 c 
ATOM   3495 H HD11 . LEU A 1 256 ? 6.977   12.567  18.21   1     20.675 ? 424 LEU A HD11 1 c 
ATOM   3496 H HD12 . LEU A 1 256 ? 7.035   13.768  19.246  1     20.674 ? 424 LEU A HD12 1 c 
ATOM   3497 H HD13 . LEU A 1 256 ? 7.65    13.942  17.794  1     20.675 ? 424 LEU A HD13 1 c 
ATOM   3498 H HD21 . LEU A 1 256 ? 4.582   15.856  17.868  1     20.26  ? 424 LEU A HD21 1 c 
ATOM   3499 H HD22 . LEU A 1 256 ? 6.028   15.967  17.227  1     20.254 ? 424 LEU A HD22 1 c 
ATOM   3500 H HD23 . LEU A 1 256 ? 5.867   15.808  18.796  1     20.311 ? 424 LEU A HD23 1 c 
ATOM   3501 N N    . SER A 1 257 ? 3.271   14.354  13.42   1     17.496 ? 425 SER A N    1 ? 
ATOM   3502 C CA   . SER A 1 257 ? 3.057   13.855  12.066  1     16.608 ? 425 SER A CA   1 ? 
ATOM   3503 C C    . SER A 1 257 ? 4.259   14.272  11.237  1     14.86  ? 425 SER A C    1 ? 
ATOM   3504 O O    . SER A 1 257 ? 4.757   15.386  11.352  1     18.043 ? 425 SER A O    1 ? 
ATOM   3505 C CB   . SER A 1 257 ? 1.751   14.341  11.482  1     17.12  ? 425 SER A CB   1 ? 
ATOM   3506 O OG   . SER A 1 257 ? 1.779   15.729  11.209  1     20.033 ? 425 SER A OG   1 ? 
ATOM   3507 H H    . SER A 1 257 ? 3.12    15.236  13.609  1     17.446 ? 425 SER A H    1 c 
ATOM   3508 H HA   . SER A 1 257 ? 3.025   12.871  12.1    1     16.541 ? 425 SER A HA   1 c 
ATOM   3509 H HB2  . SER A 1 257 ? 1.568   13.855  10.657  1     17.654 ? 425 SER A HB2  1 c 
ATOM   3510 H HB3  . SER A 1 257 ? 1.028   14.151  12.11   1     17.652 ? 425 SER A HB3  1 c 
ATOM   3511 N N    . THR A 1 258 ? 4.768   13.33   10.447  1     15.317 ? 426 THR A N    1 ? 
ATOM   3512 C CA   . THR A 1 258 ? 5.831   13.613  9.53    1     16.74  ? 426 THR A CA   1 ? 
ATOM   3513 C C    . THR A 1 258 ? 5.304   13.325  8.122   1     16.733 ? 426 THR A C    1 ? 
ATOM   3514 O O    . THR A 1 258 ? 4.89    12.204  7.839   1     15.715 ? 426 THR A O    1 ? 
ATOM   3515 C CB   . THR A 1 258 ? 7.067   12.765  9.809   1     17.949 ? 426 THR A CB   1 ? 
ATOM   3516 O OG1  . THR A 1 258 ? 7.559   13.017  11.131  1     16.656 ? 426 THR A OG1  1 ? 
ATOM   3517 C CG2  . THR A 1 258 ? 8.161   13.095  8.802   1     17.789 ? 426 THR A CG2  1 ? 
ATOM   3518 H H    . THR A 1 258 ? 4.436   12.479  10.484  1     15.537 ? 426 THR A H    1 c 
ATOM   3519 H HA   . THR A 1 258 ? 6.076   14.554  9.598   1     16.677 ? 426 THR A HA   1 c 
ATOM   3520 H HB   . THR A 1 258 ? 6.834   11.809  9.726   1     17.437 ? 426 THR A HB   1 c 
ATOM   3521 H HG21 . THR A 1 258 ? 9.024   12.833  9.164   1     17.822 ? 426 THR A HG21 1 c 
ATOM   3522 H HG22 . THR A 1 258 ? 8.163   14.05   8.623   1     17.817 ? 426 THR A HG22 1 c 
ATOM   3523 H HG23 . THR A 1 258 ? 8       12.612  7.975   1     17.82  ? 426 THR A HG23 1 c 
ATOM   3524 N N    . ASP A 1 259 ? 5.391   14.334  7.224   1     17.626 ? 427 ASP A N    1 ? 
ATOM   3525 C CA   . ASP A 1 259 ? 5.025   14.136  5.835   1     16.552 ? 427 ASP A CA   1 ? 
ATOM   3526 C C    . ASP A 1 259 ? 6.226   14.528  4.978   1     18.632 ? 427 ASP A C    1 ? 
ATOM   3527 O O    . ASP A 1 259 ? 7.202   15.093  5.479   1     16.575 ? 427 ASP A O    1 ? 
ATOM   3528 C CB   . ASP A 1 259 ? 3.743   14.865  5.491   1     15.771 ? 427 ASP A CB   1 ? 
ATOM   3529 C CG   . ASP A 1 259 ? 2.54    14.212  6.135   1     18.359 ? 427 ASP A CG   1 ? 
ATOM   3530 O OD1  . ASP A 1 259 ? 2.32    14.472  7.35    1     16.745 ? 427 ASP A OD1  1 ? 
ATOM   3531 O OD2  . ASP A 1 259 ? 1.935   13.38   5.432   1     18.215 ? 427 ASP A OD2  1 ? 
ATOM   3532 H H    . ASP A 1 259 ? 5.682   15.158  7.491   1     17.165 ? 427 ASP A H    1 c 
ATOM   3533 H HA   . ASP A 1 259 ? 4.854   13.179  5.687   1     16.966 ? 427 ASP A HA   1 c 
ATOM   3534 H HB2  . ASP A 1 259 ? 3.802   15.792  5.802   1     16.518 ? 427 ASP A HB2  1 c 
ATOM   3535 H HB3  . ASP A 1 259 ? 3.621   14.871  4.518   1     16.522 ? 427 ASP A HB3  1 c 
ATOM   3536 N N    . TYR A 1 260 ? 6.206   14.103  3.713   1     19.293 ? 428 TYR A N    1 ? 
ATOM   3537 C CA   . TYR A 1 260 ? 7.406   14.171  2.88    1     17.547 ? 428 TYR A CA   1 ? 
ATOM   3538 C C    . TYR A 1 260 ? 7.03    14.862  1.575   1     18.46  ? 428 TYR A C    1 ? 
ATOM   3539 O O    . TYR A 1 260 ? 6.274   14.281  0.793   1     19.574 ? 428 TYR A O    1 ? 
ATOM   3540 C CB   . TYR A 1 260 ? 7.891   12.738  2.662   1     16.706 ? 428 TYR A CB   1 ? 
ATOM   3541 C CG   . TYR A 1 260 ? 8.367   12.066  3.936   1     16.988 ? 428 TYR A CG   1 ? 
ATOM   3542 C CD1  . TYR A 1 260 ? 9.584   12.412  4.531   1     15.418 ? 428 TYR A CD1  1 ? 
ATOM   3543 C CD2  . TYR A 1 260 ? 7.587   11.109  4.551   1     16.43  ? 428 TYR A CD2  1 ? 
ATOM   3544 C CE1  . TYR A 1 260 ? 10.017  11.782  5.675   1     16.401 ? 428 TYR A CE1  1 ? 
ATOM   3545 C CE2  . TYR A 1 260 ? 8.028   10.447  5.688   1     17.808 ? 428 TYR A CE2  1 ? 
ATOM   3546 C CZ   . TYR A 1 260 ? 9.242   10.794  6.242   1     16.872 ? 428 TYR A CZ   1 ? 
ATOM   3547 O OH   . TYR A 1 260 ? 9.708   10.173  7.346   1     17.667 ? 428 TYR A OH   1 ? 
ATOM   3548 H H    . TYR A 1 260 ? 5.435   13.763  3.358   1     18.714 ? 428 TYR A H    1 c 
ATOM   3549 H HA   . TYR A 1 260 ? 8.106   14.687  3.343   1     17.872 ? 428 TYR A HA   1 c 
ATOM   3550 H HB2  . TYR A 1 260 ? 7.155   12.213  2.283   1     17.025 ? 428 TYR A HB2  1 c 
ATOM   3551 H HB3  . TYR A 1 260 ? 8.628   12.751  2.011   1     17.003 ? 428 TYR A HB3  1 c 
ATOM   3552 H HD1  . TYR A 1 260 ? 10.124  13.072  4.131   1     16.037 ? 428 TYR A HD1  1 c 
ATOM   3553 H HD2  . TYR A 1 260 ? 6.772   10.851  4.154   1     16.869 ? 428 TYR A HD2  1 c 
ATOM   3554 H HE1  . TYR A 1 260 ? 10.851  12.003  6.052   1     16.294 ? 428 TYR A HE1  1 c 
ATOM   3555 H HE2  . TYR A 1 260 ? 7.498   9.776   6.085   1     17.244 ? 428 TYR A HE2  1 c 
ATOM   3556 N N    . ALA A 1 261 ? 7.434   16.113  1.443   1     18.353 ? 429 ALA A N    1 ? 
ATOM   3557 C CA   . ALA A 1 261 ? 6.992   16.937  0.317   1     19.506 ? 429 ALA A CA   1 ? 
ATOM   3558 C C    . ALA A 1 261 ? 7.867   18.167  0.246   1     20.211 ? 429 ALA A C    1 ? 
ATOM   3559 O O    . ALA A 1 261 ? 8.35    18.638  1.289   1     18.855 ? 429 ALA A O    1 ? 
ATOM   3560 C CB   . ALA A 1 261 ? 5.538   17.335  0.502   1     19.653 ? 429 ALA A CB   1 ? 
ATOM   3561 H H    . ALA A 1 261 ? 7.999   16.477  2.063   1     18.627 ? 429 ALA A H    1 c 
ATOM   3562 H HA   . ALA A 1 261 ? 7.097   16.414  -0.523  1     19.427 ? 429 ALA A HA   1 c 
ATOM   3563 H HB1  . ALA A 1 261 ? 4.965   16.565  0.349   1     19.605 ? 429 ALA A HB1  1 c 
ATOM   3564 H HB2  . ALA A 1 261 ? 5.401   17.662  1.407   1     19.609 ? 429 ALA A HB2  1 c 
ATOM   3565 H HB3  . ALA A 1 261 ? 5.307   18.036  -0.131  1     19.614 ? 429 ALA A HB3  1 c 
ATOM   3566 N N    . THR A 1 262 ? 8.056   18.684  -0.975  1     19.592 ? 430 THR A N    1 ? 
ATOM   3567 C CA   . THR A 1 262 ? 8.789   19.937  -1.165  1     20.954 ? 430 THR A CA   1 ? 
ATOM   3568 C C    . THR A 1 262 ? 7.967   20.95   -1.936  1     21.541 ? 430 THR A C    1 ? 
ATOM   3569 O O    . THR A 1 262 ? 8.29    22.14   -1.848  1     26.031 ? 430 THR A O    1 ? 
ATOM   3570 C CB   . THR A 1 262 ? 10.111  19.728  -1.906  1     26.917 ? 430 THR A CB   1 ? 
ATOM   3571 O OG1  . THR A 1 262 ? 9.709   19.099  -3.141  1     26.838 ? 430 THR A OG1  1 ? 
ATOM   3572 C CG2  . THR A 1 262 ? 11.091  18.973  -1.037  1     29.491 ? 430 THR A CG2  1 ? 
ATOM   3573 H H    . THR A 1 262 ? 7.78    18.218  -1.709  1     20.024 ? 430 THR A H    1 c 
ATOM   3574 H HA   . THR A 1 262 ? 8.993   20.318  -0.284  1     21.746 ? 430 THR A HA   1 c 
ATOM   3575 H HB   . THR A 1 262 ? 10.502  20.611  -2.107  1     26.003 ? 430 THR A HB   1 c 
ATOM   3576 H HG21 . THR A 1 262 ? 11.916  18.841  -1.528  1     28.798 ? 430 THR A HG21 1 c 
ATOM   3577 H HG22 . THR A 1 262 ? 10.713  18.113  -0.795  1     28.737 ? 430 THR A HG22 1 c 
ATOM   3578 H HG23 . THR A 1 262 ? 11.273  19.485  -0.231  1     28.728 ? 430 THR A HG23 1 c 
ATOM   3579 N N    . GLN A 1 263 ? 6.889   20.541  -2.631  1     20.169 ? 431 GLN A N    1 ? 
ATOM   3580 C CA   . GLN A 1 263 ? 6.051   21.508  -3.32   1     21.325 ? 431 GLN A CA   1 ? 
ATOM   3581 C C    . GLN A 1 263 ? 5.32    22.348  -2.269  1     24.601 ? 431 GLN A C    1 ? 
ATOM   3582 O O    . GLN A 1 263 ? 4.691   21.803  -1.353  1     23.132 ? 431 GLN A O    1 ? 
ATOM   3583 C CB   . GLN A 1 263 ? 5.009   20.893  -4.252  1     23.171 ? 431 GLN A CB   1 ? 
ATOM   3584 C CG   . GLN A 1 263 ? 5.616   20.077  -5.391  1     23.729 ? 431 GLN A CG   1 ? 
ATOM   3585 C CD   . GLN A 1 263 ? 4.607   19.618  -6.421  1     21.676 ? 431 GLN A CD   1 ? 
ATOM   3586 O OE1  . GLN A 1 263 ? 3.495   20.128  -6.56   1     25.431 ? 431 GLN A OE1  1 ? 
ATOM   3587 N NE2  . GLN A 1 263 ? 5.002   18.625  -7.199  1     23.928 ? 431 GLN A NE2  1 ? 
ATOM   3588 H H    . GLN A 1 263 ? 6.677   19.656  -2.687  1     20.716 ? 431 GLN A H    1 c 
ATOM   3589 H HA   . GLN A 1 263 ? 6.637   22.101  -3.856  1     22.025 ? 431 GLN A HA   1 c 
ATOM   3590 H HB2  . GLN A 1 263 ? 4.418   20.317  -3.726  1     22.852 ? 431 GLN A HB2  1 c 
ATOM   3591 H HB3  . GLN A 1 263 ? 4.464   21.614  -4.631  1     22.88  ? 431 GLN A HB3  1 c 
ATOM   3592 H HG2  . GLN A 1 263 ? 6.299   20.617  -5.843  1     23.107 ? 431 GLN A HG2  1 c 
ATOM   3593 H HG3  . GLN A 1 263 ? 6.063   19.288  -5.018  1     23.074 ? 431 GLN A HG3  1 c 
ATOM   3594 H HE21 . GLN A 1 263 ? 4.399   18.13   -7.621  1     23.228 ? 431 GLN A HE21 1 c 
ATOM   3595 H HE22 . GLN A 1 263 ? 5.866   18.455  -7.302  1     23.219 ? 431 GLN A HE22 1 c 
ATOM   3596 N N    . SER A 1 264 ? 5.356   23.676  -2.439  1     23.803 ? 432 SER A N    1 ? 
ATOM   3597 C CA   . SER A 1 264 ? 4.915   24.576  -1.389  1     26.33  ? 432 SER A CA   1 ? 
ATOM   3598 C C    . SER A 1 264 ? 3.435   24.368  -1.052  1     27.472 ? 432 SER A C    1 ? 
ATOM   3599 O O    . SER A 1 264 ? 3.087   24.429  0.125   1     22.109 ? 432 SER A O    1 ? 
ATOM   3600 C CB   . SER A 1 264 ? 5.241   26.017  -1.745  1     32.625 ? 432 SER A CB   1 ? 
ATOM   3601 O OG   . SER A 1 264 ? 4.337   26.472  -2.733  1     38.077 ? 432 SER A OG   1 ? 
ATOM   3602 H H    . SER A 1 264 ? 5.654   24.027  -3.228  1     24.595 ? 432 SER A H    1 c 
ATOM   3603 H HA   . SER A 1 264 ? 5.434   24.349  -0.575  1     27.035 ? 432 SER A HA   1 c 
ATOM   3604 H HB2  . SER A 1 264 ? 5.166   26.571  -0.951  1     32.239 ? 432 SER A HB2  1 c 
ATOM   3605 H HB3  . SER A 1 264 ? 6.155   26.074  -2.082  1     32.201 ? 432 SER A HB3  1 c 
ATOM   3606 N N    . ALA A 1 265 ? 2.559   24.062  -2.031  1     20.733 ? 433 ALA A N    1 ? 
ATOM   3607 C CA   . ALA A 1 265 ? 1.154   23.857  -1.713  1     23.696 ? 433 ALA A CA   1 ? 
ATOM   3608 C C    . ALA A 1 265 ? 0.949   22.583  -0.879  1     23.216 ? 433 ALA A C    1 ? 
ATOM   3609 O O    . ALA A 1 265 ? 0.013   22.511  -0.064  1     22.91  ? 433 ALA A O    1 ? 
ATOM   3610 C CB   . ALA A 1 265 ? 0.317   23.851  -2.96   1     26.232 ? 433 ALA A CB   1 ? 
ATOM   3611 H H    . ALA A 1 265 ? 2.839   23.989  -2.898  1     22.879 ? 433 ALA A H    1 c 
ATOM   3612 H HA   . ALA A 1 265 ? 0.859   24.627  -1.152  1     23.456 ? 433 ALA A HA   1 c 
ATOM   3613 H HB1  . ALA A 1 265 ? 0.405   24.704  -3.417  1     25.448 ? 433 ALA A HB1  1 c 
ATOM   3614 H HB2  . ALA A 1 265 ? 0.616   23.139  -3.55   1     25.448 ? 433 ALA A HB2  1 c 
ATOM   3615 H HB3  . ALA A 1 265 ? -0.615  23.706  -2.727  1     25.448 ? 433 ALA A HB3  1 c 
ATOM   3616 N N    . HIS A 1 266 ? 1.79    21.565  -1.127  1     22.69  ? 434 HIS A N    1 ? 
ATOM   3617 C CA   . HIS A 1 266 ? 1.708   20.301  -0.408  1     19.688 ? 434 HIS A CA   1 ? 
ATOM   3618 C C    . HIS A 1 266 ? 2.239   20.478  1.014   1     20.241 ? 434 HIS A C    1 ? 
ATOM   3619 O O    . HIS A 1 266 ? 1.651   19.954  1.956   1     18.399 ? 434 HIS A O    1 ? 
ATOM   3620 C CB   . HIS A 1 266 ? 2.488   19.214  -1.14   1     19.994 ? 434 HIS A CB   1 ? 
ATOM   3621 C CG   . HIS A 1 266 ? 1.997   18.949  -2.516  1     20.564 ? 434 HIS A CG   1 ? 
ATOM   3622 N ND1  . HIS A 1 266 ? 2.749   18.208  -3.419  1     20.644 ? 434 HIS A ND1  1 ? 
ATOM   3623 C CD2  . HIS A 1 266 ? 0.857   19.271  -3.15   1     20.995 ? 434 HIS A CD2  1 ? 
ATOM   3624 C CE1  . HIS A 1 266 ? 2.066   18.084  -4.536  1     21.208 ? 434 HIS A CE1  1 ? 
ATOM   3625 N NE2  . HIS A 1 266 ? 0.918   18.699  -4.422  1     21.86  ? 434 HIS A NE2  1 ? 
ATOM   3626 H H    . HIS A 1 266 ? 2.433   21.66   -1.768  1     22.07  ? 434 HIS A H    1 c 
ATOM   3627 H HA   . HIS A 1 266 ? 0.758   20.029  -0.355  1     20.429 ? 434 HIS A HA   1 c 
ATOM   3628 H HB2  . HIS A 1 266 ? 3.432   19.478  -1.184  1     20.071 ? 434 HIS A HB2  1 c 
ATOM   3629 H HB3  . HIS A 1 266 ? 2.435   18.384  -0.618  1     20.058 ? 434 HIS A HB3  1 c 
ATOM   3630 H HD2  . HIS A 1 266 ? 0.141   19.756  -2.793  1     21.18  ? 434 HIS A HD2  1 c 
ATOM   3631 H HE1  . HIS A 1 266 ? 2.372   17.632  -5.304  1     21.218 ? 434 HIS A HE1  1 c 
ATOM   3632 N N    . VAL A 1 267 ? 3.37    21.178  1.162   1     17.913 ? 435 VAL A N    1 ? 
ATOM   3633 C CA   . VAL A 1 267 ? 3.902   21.481  2.485   1     18.926 ? 435 VAL A CA   1 ? 
ATOM   3634 C C    . VAL A 1 267 ? 2.825   22.185  3.316   1     19.238 ? 435 VAL A C    1 ? 
ATOM   3635 O O    . VAL A 1 267 ? 2.471   21.737  4.416   1     16.522 ? 435 VAL A O    1 ? 
ATOM   3636 C CB   . VAL A 1 267 ? 5.186   22.301  2.363   1     18.486 ? 435 VAL A CB   1 ? 
ATOM   3637 C CG1  . VAL A 1 267 ? 5.673   22.827  3.701   1     21.323 ? 435 VAL A CG1  1 ? 
ATOM   3638 C CG2  . VAL A 1 267 ? 6.251   21.54   1.6     1     18.809 ? 435 VAL A CG2  1 ? 
ATOM   3639 H H    . VAL A 1 267 ? 3.812   21.482  0.422   1     18.703 ? 435 VAL A H    1 c 
ATOM   3640 H HA   . VAL A 1 267 ? 4.121   20.635  2.922   1     18.7   ? 435 VAL A HA   1 c 
ATOM   3641 H HB   . VAL A 1 267 ? 4.961   23.091  1.818   1     19.136 ? 435 VAL A HB   1 c 
ATOM   3642 H HG11 . VAL A 1 267 ? 5.528   22.154  4.387   1     20.42  ? 435 VAL A HG11 1 c 
ATOM   3643 H HG12 . VAL A 1 267 ? 5.184   23.634  3.932   1     20.426 ? 435 VAL A HG12 1 c 
ATOM   3644 H HG13 . VAL A 1 267 ? 6.622   23.032  3.647   1     20.414 ? 435 VAL A HG13 1 c 
ATOM   3645 H HG21 . VAL A 1 267 ? 7.119   21.949  1.753   1     18.745 ? 435 VAL A HG21 1 c 
ATOM   3646 H HG22 . VAL A 1 267 ? 6.053   21.561  0.652   1     18.741 ? 435 VAL A HG22 1 c 
ATOM   3647 H HG23 . VAL A 1 267 ? 6.271   20.617  1.904   1     18.725 ? 435 VAL A HG23 1 c 
ATOM   3648 N N    . ALA A 1 268 ? 2.217   23.212  2.727   1     18.393 ? 436 ALA A N    1 ? 
ATOM   3649 C CA   . ALA A 1 268 ? 1.216   23.997  3.435   1     18.61  ? 436 ALA A CA   1 ? 
ATOM   3650 C C    . ALA A 1 268 ? 0.02    23.132  3.814   1     17.422 ? 436 ALA A C    1 ? 
ATOM   3651 O O    . ALA A 1 268 ? -0.572  23.29   4.879   1     18.549 ? 436 ALA A O    1 ? 
ATOM   3652 C CB   . ALA A 1 268 ? 0.758   25.155  2.553   1     22.126 ? 436 ALA A CB   1 ? 
ATOM   3653 H H    . ALA A 1 268 ? 2.434   23.44   1.869   1     18.66  ? 436 ALA A H    1 c 
ATOM   3654 H HA   . ALA A 1 268 ? 1.626   24.352  4.269   1     18.954 ? 436 ALA A HA   1 c 
ATOM   3655 H HB1  . ALA A 1 268 ? 1.511   25.741  2.364   1     21.037 ? 436 ALA A HB1  1 c 
ATOM   3656 H HB2  . ALA A 1 268 ? 0.404   24.809  1.716   1     21.031 ? 436 ALA A HB2  1 c 
ATOM   3657 H HB3  . ALA A 1 268 ? 0.065   25.66   3.01    1     21.037 ? 436 ALA A HB3  1 c 
ATOM   3658 N N    . ASP A 1 269 ? -0.367  22.217  2.913   1     17.347 ? 437 ASP A N    1 ? 
ATOM   3659 C CA   . ASP A 1 269 ? -1.532  21.39   3.137   1     19.084 ? 437 ASP A CA   1 ? 
ATOM   3660 C C    . ASP A 1 269 ? -1.273  20.424  4.303   1     17.718 ? 437 ASP A C    1 ? 
ATOM   3661 O O    . ASP A 1 269 ? -2.155  20.194  5.132   1     16.875 ? 437 ASP A O    1 ? 
ATOM   3662 C CB   . ASP A 1 269 ? -1.894  20.637  1.867   1     20.501 ? 437 ASP A CB   1 ? 
ATOM   3663 C CG   . ASP A 1 269 ? -3.182  19.835  1.952   1     22.739 ? 437 ASP A CG   1 ? 
ATOM   3664 O OD1  . ASP A 1 269 ? -4.245  20.462  2.08    1     24.072 ? 437 ASP A OD1  1 ? 
ATOM   3665 O OD2  . ASP A 1 269 ? -3.104  18.599  1.899   1     21.359 ? 437 ASP A OD2  1 ? 
ATOM   3666 H H    . ASP A 1 269 ? 0.101   22.118  2.134   1     17.784 ? 437 ASP A H    1 c 
ATOM   3667 H HA   . ASP A 1 269 ? -2.289  21.974  3.371   1     18.721 ? 437 ASP A HA   1 c 
ATOM   3668 H HB2  . ASP A 1 269 ? -1.995  21.285  1.14    1     20.665 ? 437 ASP A HB2  1 c 
ATOM   3669 H HB3  . ASP A 1 269 ? -1.154  20.04   1.636   1     20.645 ? 437 ASP A HB3  1 c 
ATOM   3670 N N    . ALA A 1 270 ? -0.079  19.831  4.36    1     17.45  ? 438 ALA A N    1 ? 
ATOM   3671 C CA   . ALA A 1 270 ? 0.246   18.92   5.472   1     17.685 ? 438 ALA A CA   1 ? 
ATOM   3672 C C    . ALA A 1 270 ? 0.232   19.694  6.802   1     18.398 ? 438 ALA A C    1 ? 
ATOM   3673 O O    . ALA A 1 270 ? -0.41   19.259  7.763   1     18.494 ? 438 ALA A O    1 ? 
ATOM   3674 C CB   . ALA A 1 270 ? 1.581   18.255  5.306   1     17.899 ? 438 ALA A CB   1 ? 
ATOM   3675 H H    . ALA A 1 270 ? 0.542   19.976  3.706   1     17.576 ? 438 ALA A H    1 c 
ATOM   3676 H HA   . ALA A 1 270 ? -0.461  18.218  5.515   1     17.801 ? 438 ALA A HA   1 c 
ATOM   3677 H HB1  . ALA A 1 270 ? 1.597   17.758  4.472   1     17.84  ? 438 ALA A HB1  1 c 
ATOM   3678 H HB2  . ALA A 1 270 ? 2.282   18.928  5.292   1     17.836 ? 438 ALA A HB2  1 c 
ATOM   3679 H HB3  . ALA A 1 270 ? 1.737   17.645  6.046   1     17.836 ? 438 ALA A HB3  1 c 
ATOM   3680 N N    . TYR A 1 271 ? 0.924   20.828  6.854   1     20.35  ? 439 TYR A N    1 ? 
ATOM   3681 C CA   . TYR A 1 271 ? 0.992   21.604  8.09    1     17.771 ? 439 TYR A CA   1 ? 
ATOM   3682 C C    . TYR A 1 271 ? -0.414  22.025  8.525   1     21.6   ? 439 TYR A C    1 ? 
ATOM   3683 O O    . TYR A 1 271 ? -0.769  21.884  9.69    1     18.899 ? 439 TYR A O    1 ? 
ATOM   3684 C CB   . TYR A 1 271 ? 1.869   22.835  8       1     17.373 ? 439 TYR A CB   1 ? 
ATOM   3685 C CG   . TYR A 1 271 ? 3.333   22.532  8.232   1     17.303 ? 439 TYR A CG   1 ? 
ATOM   3686 C CD1  . TYR A 1 271 ? 3.884   22.579  9.501   1     16.492 ? 439 TYR A CD1  1 ? 
ATOM   3687 C CD2  . TYR A 1 271 ? 4.159   22.138  7.187   1     18.024 ? 439 TYR A CD2  1 ? 
ATOM   3688 C CE1  . TYR A 1 271 ? 5.223   22.281  9.73    1     16.629 ? 439 TYR A CE1  1 ? 
ATOM   3689 C CE2  . TYR A 1 271 ? 5.492   21.832  7.409   1     18.357 ? 439 TYR A CE2  1 ? 
ATOM   3690 C CZ   . TYR A 1 271 ? 6.032   21.908  8.681   1     18.775 ? 439 TYR A CZ   1 ? 
ATOM   3691 O OH   . TYR A 1 271 ? 7.347   21.612  8.934   1     18.086 ? 439 TYR A OH   1 ? 
ATOM   3692 H H    . TYR A 1 271 ? 1.372   21.127  6.115   1     19.223 ? 439 TYR A H    1 c 
ATOM   3693 H HA   . TYR A 1 271 ? 1.366   21.013  8.797   1     18.817 ? 439 TYR A HA   1 c 
ATOM   3694 H HB2  . TYR A 1 271 ? 1.761   23.236  7.109   1     17.463 ? 439 TYR A HB2  1 c 
ATOM   3695 H HB3  . TYR A 1 271 ? 1.569   23.49   8.67    1     17.472 ? 439 TYR A HB3  1 c 
ATOM   3696 H HD1  . TYR A 1 271 ? 3.341   22.839  10.227  1     16.779 ? 439 TYR A HD1  1 c 
ATOM   3697 H HD2  . TYR A 1 271 ? 3.812   22.085  6.315   1     17.908 ? 439 TYR A HD2  1 c 
ATOM   3698 H HE1  . TYR A 1 271 ? 5.577   22.333  10.602  1     17.093 ? 439 TYR A HE1  1 c 
ATOM   3699 H HE2  . TYR A 1 271 ? 6.039   21.583  6.686   1     18.333 ? 439 TYR A HE2  1 c 
ATOM   3700 N N    . THR A 1 272 ? -1.224  22.49   7.569   1     19.284 ? 440 THR A N    1 ? 
ATOM   3701 C CA   . THR A 1 272 ? -2.533  23.027  7.882   1     19.545 ? 440 THR A CA   1 ? 
ATOM   3702 C C    . THR A 1 272 ? -3.45   21.946  8.427   1     18.003 ? 440 THR A C    1 ? 
ATOM   3703 O O    . THR A 1 272 ? -4.164  22.159  9.418   1     19.166 ? 440 THR A O    1 ? 
ATOM   3704 C CB   . THR A 1 272 ? -3.142  23.693  6.648   1     20.969 ? 440 THR A CB   1 ? 
ATOM   3705 O OG1  . THR A 1 272 ? -2.237  24.75   6.332   1     21.84  ? 440 THR A OG1  1 ? 
ATOM   3706 C CG2  . THR A 1 272 ? -4.522  24.265  6.916   1     21.923 ? 440 THR A CG2  1 ? 
ATOM   3707 H H    . THR A 1 272 ? -0.949  22.481  6.697   1     19.869 ? 440 THR A H    1 c 
ATOM   3708 H HA   . THR A 1 272 ? -2.421  23.714  8.575   1     19.458 ? 440 THR A HA   1 c 
ATOM   3709 H HB   . THR A 1 272 ? -3.181  23.053  5.897   1     21.041 ? 440 THR A HB   1 c 
ATOM   3710 H HG21 . THR A 1 272 ? -4.689  25.006  6.31    1     21.626 ? 440 THR A HG21 1 c 
ATOM   3711 H HG22 . THR A 1 272 ? -4.57   24.582  7.834   1     21.602 ? 440 THR A HG22 1 c 
ATOM   3712 H HG23 . THR A 1 272 ? -5.193  23.576  6.776   1     21.611 ? 440 THR A HG23 1 c 
ATOM   3713 N N    . ARG A 1 273 ? -3.519  20.806  7.731   1     16.842 ? 441 ARG A N    1 ? 
ATOM   3714 C CA   . ARG A 1 273 ? -4.474  19.784  8.094   1     16.034 ? 441 ARG A CA   1 ? 
ATOM   3715 C C    . ARG A 1 273 ? -4.012  19.114  9.381   1     18.473 ? 441 ARG A C    1 ? 
ATOM   3716 O O    . ARG A 1 273 ? -4.841  18.769  10.234  1     17.68  ? 441 ARG A O    1 ? 
ATOM   3717 C CB   . ARG A 1 273 ? -4.538  18.743  6.967   1     17.186 ? 441 ARG A CB   1 ? 
ATOM   3718 C CG   . ARG A 1 273 ? -5.284  19.296  5.757   1     18.806 ? 441 ARG A CG   1 ? 
ATOM   3719 C CD   . ARG A 1 273 ? -5.119  18.423  4.523   1     20.649 ? 441 ARG A CD   1 ? 
ATOM   3720 N NE   . ARG A 1 273 ? -5.661  17.072  4.665   1     21.153 ? 441 ARG A NE   1 ? 
ATOM   3721 C CZ   . ARG A 1 273 ? -5.431  16.111  3.777   1     20.704 ? 441 ARG A CZ   1 ? 
ATOM   3722 N NH1  . ARG A 1 273 ? -4.58   16.324  2.798   1     21.623 ? 441 ARG A NH1  1 ? 
ATOM   3723 N NH2  . ARG A 1 273 ? -6.008  14.928  3.907   1     20.475 ? 441 ARG A NH2  1 ? 
ATOM   3724 H H    . ARG A 1 273 ? -2.966  20.67   7.016   1     16.958 ? 441 ARG A H    1 c 
ATOM   3725 H HA   . ARG A 1 273 ? -5.363  20.2    8.232   1     16.874 ? 441 ARG A HA   1 c 
ATOM   3726 H HB2  . ARG A 1 273 ? -3.629  18.488  6.7     1     17.28  ? 441 ARG A HB2  1 c 
ATOM   3727 H HB3  . ARG A 1 273 ? -4.999  17.939  7.29    1     17.332 ? 441 ARG A HB3  1 c 
ATOM   3728 H HG2  . ARG A 1 273 ? -6.24   19.367  5.972   1     18.821 ? 441 ARG A HG2  1 c 
ATOM   3729 H HG3  . ARG A 1 273 ? -4.953  20.198  5.556   1     18.813 ? 441 ARG A HG3  1 c 
ATOM   3730 H HD2  . ARG A 1 273 ? -5.556  18.863  3.766   1     20.353 ? 441 ARG A HD2  1 c 
ATOM   3731 H HD3  . ARG A 1 273 ? -4.163  18.365  4.321   1     20.347 ? 441 ARG A HD3  1 c 
ATOM   3732 H HE   . ARG A 1 273 ? -6.155  16.891  5.36    1     20.909 ? 441 ARG A HE   1 c 
ATOM   3733 H HH11 . ARG A 1 273 ? -4.815  16.834  2.116   1     21.332 ? 441 ARG A HH11 1 c 
ATOM   3734 H HH12 . ARG A 1 273 ? -3.777  15.955  2.826   1     21.335 ? 441 ARG A HH12 1 c 
ATOM   3735 H HH21 . ARG A 1 273 ? -6.144  14.591  4.714   1     20.548 ? 441 ARG A HH21 1 c 
ATOM   3736 H HH22 . ARG A 1 273 ? -6.256  14.478  3.187   1     20.546 ? 441 ARG A HH22 1 c 
ATOM   3737 N N    . SER A 1 274 ? -2.677  18.923  9.52    1     16.073 ? 442 SER A N    1 ? 
ATOM   3738 C CA   . SER A 1 274 ? -2.154  18.307  10.748  1     17.039 ? 442 SER A CA   1 ? 
ATOM   3739 C C    . SER A 1 274 ? -2.548  19.122  11.987  1     17.848 ? 442 SER A C    1 ? 
ATOM   3740 O O    . SER A 1 274 ? -3.047  18.577  12.99   1     19.523 ? 442 SER A O    1 ? 
ATOM   3741 C CB   . SER A 1 274 ? -0.666  18.113  10.675  1     18.217 ? 442 SER A CB   1 ? 
ATOM   3742 O OG   . SER A 1 274 ? -0.189  17.574  11.916  1     20.537 ? 442 SER A OG   1 ? 
ATOM   3743 H H    . SER A 1 274 ? -2.098  19.157  8.852   1     16.838 ? 442 SER A H    1 c 
ATOM   3744 H HA   . SER A 1 274 ? -2.572  17.414  10.834  1     17.217 ? 442 SER A HA   1 c 
ATOM   3745 H HB2  . SER A 1 274 ? -0.45   17.502  9.945   1     18.457 ? 442 SER A HB2  1 c 
ATOM   3746 H HB3  . SER A 1 274 ? -0.24   18.971  10.501  1     18.435 ? 442 SER A HB3  1 c 
ATOM   3747 N N    . ARG A 1 275 ? -2.295  20.434  11.942  1     18.737 ? 443 ARG A N    1 ? 
ATOM   3748 C CA   . ARG A 1 275 ? -2.62   21.329  13.039  1     18.45  ? 443 ARG A CA   1 ? 
ATOM   3749 C C    . ARG A 1 275 ? -4.134  21.374  13.273  1     20.79  ? 443 ARG A C    1 ? 
ATOM   3750 O O    . ARG A 1 275 ? -4.562  21.344  14.411  1     18.45  ? 443 ARG A O    1 ? 
ATOM   3751 C CB   . ARG A 1 275 ? -1.996  22.701  12.805  1     19.459 ? 443 ARG A CB   1 ? 
ATOM   3752 C CG   . ARG A 1 275 ? -0.488  22.727  12.958  1     19.975 ? 443 ARG A CG   1 ? 
ATOM   3753 C CD   . ARG A 1 275 ? 0.171   23.989  12.536  1     21.194 ? 443 ARG A CD   1 ? 
ATOM   3754 N NE   . ARG A 1 275 ? 1.584   23.948  12.891  1     21.154 ? 443 ARG A NE   1 ? 
ATOM   3755 C CZ   . ARG A 1 275 ? 2.502   24.719  12.308  1     25.003 ? 443 ARG A CZ   1 ? 
ATOM   3756 N NH1  . ARG A 1 275 ? 2.094   25.66   11.48   1     26.291 ? 443 ARG A NH1  1 ? 
ATOM   3757 N NH2  . ARG A 1 275 ? 3.782   24.526  12.539  1     25.288 ? 443 ARG A NH2  1 ? 
ATOM   3758 H H    . ARG A 1 275 ? -1.896  20.783  11.198  1     18.444 ? 443 ARG A H    1 c 
ATOM   3759 H HA   . ARG A 1 275 ? -2.202  20.96   13.859  1     19.094 ? 443 ARG A HA   1 c 
ATOM   3760 H HB2  . ARG A 1 275 ? -2.227  23.003  11.901  1     19.336 ? 443 ARG A HB2  1 c 
ATOM   3761 H HB3  . ARG A 1 275 ? -2.387  23.337  13.441  1     19.347 ? 443 ARG A HB3  1 c 
ATOM   3762 H HG2  . ARG A 1 275 ? -0.268  22.559  13.9    1     20.136 ? 443 ARG A HG2  1 c 
ATOM   3763 H HG3  . ARG A 1 275 ? -0.11   21.989  12.438  1     20.087 ? 443 ARG A HG3  1 c 
ATOM   3764 H HD2  . ARG A 1 275 ? 0.069   24.117  11.57   1     20.946 ? 443 ARG A HD2  1 c 
ATOM   3765 H HD3  . ARG A 1 275 ? -0.246  24.732  13.001  1     20.905 ? 443 ARG A HD3  1 c 
ATOM   3766 H HE   . ARG A 1 275 ? 1.847   23.399  13.515  1     22.032 ? 443 ARG A HE   1 c 
ATOM   3767 H HH11 . ARG A 1 275 ? 1.951   26.473  11.791  1     25.875 ? 443 ARG A HH11 1 c 
ATOM   3768 H HH12 . ARG A 1 275 ? 1.951   25.467  10.632  1     25.838 ? 443 ARG A HH12 1 c 
ATOM   3769 H HH21 . ARG A 1 275 ? 4.08    23.711  12.708  1     25.173 ? 443 ARG A HH21 1 c 
ATOM   3770 H HH22 . ARG A 1 275 ? 4.339   25.212  12.523  1     25.194 ? 443 ARG A HH22 1 c 
ATOM   3771 N N    . ALA A 1 276 ? -4.942  21.368  12.209  1     19.609 ? 444 ALA A N    1 ? 
ATOM   3772 C CA   . ALA A 1 276 ? -6.402  21.353  12.353  1     20.676 ? 444 ALA A CA   1 ? 
ATOM   3773 C C    . ALA A 1 276 ? -6.898  20.102  13.078  1     21.725 ? 444 ALA A C    1 ? 
ATOM   3774 O O    . ALA A 1 276 ? -7.863  20.169  13.823  1     22.219 ? 444 ALA A O    1 ? 
ATOM   3775 C CB   . ALA A 1 276 ? -7.06   21.515  11.007  1     21.209 ? 444 ALA A CB   1 ? 
ATOM   3776 H H    . ALA A 1 276 ? -4.583  21.384  11.369  1     20.108 ? 444 ALA A H    1 c 
ATOM   3777 H HA   . ALA A 1 276 ? -6.652  22.138  12.915  1     20.737 ? 444 ALA A HA   1 c 
ATOM   3778 H HB1  . ALA A 1 276 ? -6.795  22.363  10.614  1     21.049 ? 444 ALA A HB1  1 c 
ATOM   3779 H HB2  . ALA A 1 276 ? -6.787  20.79   10.421  1     21.049 ? 444 ALA A HB2  1 c 
ATOM   3780 H HB3  . ALA A 1 276 ? -8.026  21.496  11.111  1     21.049 ? 444 ALA A HB3  1 c 
ATOM   3781 N N    . ALA A 1 277 ? -6.206  18.975  12.921  1     21.363 ? 445 ALA A N    1 ? 
ATOM   3782 C CA   . ALA A 1 277 ? -6.574  17.723  13.575  1     20.638 ? 445 ALA A CA   1 ? 
ATOM   3783 C C    . ALA A 1 277 ? -6.074  17.652  15.022  1     22.739 ? 445 ALA A C    1 ? 
ATOM   3784 O O    . ALA A 1 277 ? -6.417  16.712  15.74   1     25.889 ? 445 ALA A O    1 ? 
ATOM   3785 C CB   . ALA A 1 277 ? -6.039  16.558  12.743  1     20.928 ? 445 ALA A CB   1 ? 
ATOM   3786 H H    . ALA A 1 277 ? -5.476  18.975  12.37   1     21.261 ? 445 ALA A H    1 c 
ATOM   3787 H HA   . ALA A 1 277 ? -7.569  17.665  13.594  1     21.211 ? 445 ALA A HA   1 c 
ATOM   3788 H HB1  . ALA A 1 277 ? -6.428  16.586  11.853  1     20.843 ? 445 ALA A HB1  1 c 
ATOM   3789 H HB2  . ALA A 1 277 ? -5.071  16.624  12.672  1     20.843 ? 445 ALA A HB2  1 c 
ATOM   3790 H HB3  . ALA A 1 277 ? -6.272  15.717  13.17   1     20.843 ? 445 ALA A HB3  1 c 
ATOM   3791 N N    . GLY A 1 278 ? -5.274  18.617  15.463  1     20.632 ? 446 GLY A N    1 ? 
ATOM   3792 C CA   . GLY A 1 278 ? -4.731  18.633  16.808  1     22.593 ? 446 GLY A CA   1 ? 
ATOM   3793 C C    . GLY A 1 278 ? -3.345  17.993  16.895  1     19.837 ? 446 GLY A C    1 ? 
ATOM   3794 O O    . GLY A 1 278 ? -2.88   17.647  17.981  1     20.372 ? 446 GLY A O    1 ? 
ATOM   3795 H H    . GLY A 1 278 ? -5.043  19.298  14.901  1     21.523 ? 446 GLY A H    1 c 
ATOM   3796 H HA2  . GLY A 1 278 ? -4.673  19.569  17.113  1     21.483 ? 446 GLY A HA2  1 c 
ATOM   3797 H HA3  . GLY A 1 278 ? -5.347  18.161  17.416  1     21.509 ? 446 GLY A HA3  1 c 
ATOM   3798 N N    . PHE A 1 279 ? -2.726  17.74   15.73   1     19.091 ? 447 PHE A N    1 ? 
ATOM   3799 C CA   . PHE A 1 279 ? -1.429  17.079  15.701  1     17.578 ? 447 PHE A CA   1 ? 
ATOM   3800 C C    . PHE A 1 279 ? -0.339  18.139  15.57   1     18.853 ? 447 PHE A C    1 ? 
ATOM   3801 O O    . PHE A 1 279 ? -0.598  19.315  15.326  1     21.18  ? 447 PHE A O    1 ? 
ATOM   3802 C CB   . PHE A 1 279 ? -1.322  16.076  14.542  1     16.466 ? 447 PHE A CB   1 ? 
ATOM   3803 C CG   . PHE A 1 279 ? -2.474  15.108  14.344  1     17.409 ? 447 PHE A CG   1 ? 
ATOM   3804 C CD1  . PHE A 1 279 ? -3.3    14.731  15.412  1     17.518 ? 447 PHE A CD1  1 ? 
ATOM   3805 C CD2  . PHE A 1 279 ? -2.708  14.544  13.089  1     16.425 ? 447 PHE A CD2  1 ? 
ATOM   3806 C CE1  . PHE A 1 279 ? -4.337  13.833  15.209  1     18.412 ? 447 PHE A CE1  1 ? 
ATOM   3807 C CE2  . PHE A 1 279 ? -3.761  13.652  12.877  1     17.705 ? 447 PHE A CE2  1 ? 
ATOM   3808 C CZ   . PHE A 1 279 ? -4.57   13.285  13.946  1     17.916 ? 447 PHE A CZ   1 ? 
ATOM   3809 H H    . PHE A 1 279 ? -3.109  17.989  14.939  1     18.965 ? 447 PHE A H    1 c 
ATOM   3810 H HA   . PHE A 1 279 ? -1.293  16.587  16.553  1     17.902 ? 447 PHE A HA   1 c 
ATOM   3811 H HB2  . PHE A 1 279 ? -1.213  16.586  13.715  1     16.961 ? 447 PHE A HB2  1 c 
ATOM   3812 H HB3  . PHE A 1 279 ? -0.499  15.554  14.667  1     16.933 ? 447 PHE A HB3  1 c 
ATOM   3813 H HD1  . PHE A 1 279 ? -3.151  15.09   16.272  1     17.693 ? 447 PHE A HD1  1 c 
ATOM   3814 H HD2  . PHE A 1 279 ? -2.158  14.793  12.363  1     16.957 ? 447 PHE A HD2  1 c 
ATOM   3815 H HE1  . PHE A 1 279 ? -4.891  13.591  15.934  1     18.065 ? 447 PHE A HE1  1 c 
ATOM   3816 H HE2  . PHE A 1 279 ? -3.908  13.284  12.02   1     17.454 ? 447 PHE A HE2  1 c 
ATOM   3817 H HZ   . PHE A 1 279 ? -5.282  12.679  13.815  1     17.96  ? 447 PHE A HZ   1 c 
ATOM   3818 N N    . VAL A 1 280 ? 0.907   17.686  15.717  1     15.864 ? 448 VAL A N    1 ? 
ATOM   3819 C CA   . VAL A 1 280 ? 2.068   18.55   15.574  1     16.821 ? 448 VAL A CA   1 ? 
ATOM   3820 C C    . VAL A 1 280 ? 2.819   18.076  14.337  1     16.14  ? 448 VAL A C    1 ? 
ATOM   3821 O O    . VAL A 1 280 ? 3.401   17.001  14.331  1     16.519 ? 448 VAL A O    1 ? 
ATOM   3822 C CB   . VAL A 1 280 ? 2.932   18.484  16.832  1     17.828 ? 448 VAL A CB   1 ? 
ATOM   3823 C CG1  . VAL A 1 280 ? 4.212   19.26   16.651  1     17.77  ? 448 VAL A CG1  1 ? 
ATOM   3824 C CG2  . VAL A 1 280 ? 2.13    19.02   18.016  1     19.283 ? 448 VAL A CG2  1 ? 
ATOM   3825 H H    . VAL A 1 280 ? 1.042   16.806  15.924  1     16.756 ? 448 VAL A H    1 c 
ATOM   3826 H HA   . VAL A 1 280 ? 1.775   19.467  15.452  1     16.749 ? 448 VAL A HA   1 c 
ATOM   3827 H HB   . VAL A 1 280 ? 3.151   17.537  16.996  1     17.895 ? 448 VAL A HB   1 c 
ATOM   3828 H HG11 . VAL A 1 280 ? 4.035   20.065  16.135  1     17.773 ? 448 VAL A HG11 1 c 
ATOM   3829 H HG12 . VAL A 1 280 ? 4.861   18.712  16.181  1     17.76  ? 448 VAL A HG12 1 c 
ATOM   3830 H HG13 . VAL A 1 280 ? 4.571   19.507  17.52   1     17.805 ? 448 VAL A HG13 1 c 
ATOM   3831 H HG21 . VAL A 1 280 ? 2.698   19.059  18.803  1     18.835 ? 448 VAL A HG21 1 c 
ATOM   3832 H HG22 . VAL A 1 280 ? 1.377   18.431  18.193  1     18.821 ? 448 VAL A HG22 1 c 
ATOM   3833 H HG23 . VAL A 1 280 ? 1.802   19.911  17.809  1     18.824 ? 448 VAL A HG23 1 c 
ATOM   3834 N N    . PRO A 1 281 ? 2.832   18.889  13.268  1     16.438 ? 449 PRO A N    1 ? 
ATOM   3835 C CA   . PRO A 1 281 ? 3.458   18.5    12.004  1     16.437 ? 449 PRO A CA   1 ? 
ATOM   3836 C C    . PRO A 1 281 ? 4.915   18.87   11.815  1     14.567 ? 449 PRO A C    1 ? 
ATOM   3837 O O    . PRO A 1 281 ? 5.435   19.85   12.377  1     15.222 ? 449 PRO A O    1 ? 
ATOM   3838 C CB   . PRO A 1 281 ? 2.608   19.239  10.93   1     16.421 ? 449 PRO A CB   1 ? 
ATOM   3839 C CG   . PRO A 1 281 ? 2.173   20.467  11.664  1     16.818 ? 449 PRO A CG   1 ? 
ATOM   3840 C CD   . PRO A 1 281 ? 1.951   20.039  13.107  1     18.209 ? 449 PRO A CD   1 ? 
ATOM   3841 H HA   . PRO A 1 281 ? 3.345   17.529  11.888  1     16.095 ? 449 PRO A HA   1 c 
ATOM   3842 H HB2  . PRO A 1 281 ? 3.151   19.471  10.14   1     16.511 ? 449 PRO A HB2  1 c 
ATOM   3843 H HB3  . PRO A 1 281 ? 1.848   18.696  10.65   1     16.556 ? 449 PRO A HB3  1 c 
ATOM   3844 H HG2  . PRO A 1 281 ? 2.864   21.158  11.62   1     17.028 ? 449 PRO A HG2  1 c 
ATOM   3845 H HG3  . PRO A 1 281 ? 1.348   20.824  11.277  1     17.048 ? 449 PRO A HG3  1 c 
ATOM   3846 H HD2  . PRO A 1 281 ? 2.193   20.763  13.726  1     17.485 ? 449 PRO A HD2  1 c 
ATOM   3847 H HD3  . PRO A 1 281 ? 1.012   19.79   13.256  1     17.479 ? 449 PRO A HD3  1 c 
ATOM   3848 N N    . TYR A 1 282 ? 5.52    18.073  10.949  1     15.404 ? 450 TYR A N    1 ? 
ATOM   3849 C CA   . TYR A 1 282 ? 6.793   18.359  10.312  1     15.625 ? 450 TYR A CA   1 ? 
ATOM   3850 C C    . TYR A 1 282 ? 6.735   17.802  8.904   1     15.283 ? 450 TYR A C    1 ? 
ATOM   3851 O O    . TYR A 1 282 ? 6.081   16.783  8.656   1     16.675 ? 450 TYR A O    1 ? 
ATOM   3852 C CB   . TYR A 1 282 ? 7.929   17.661  11.051  1     16.519 ? 450 TYR A CB   1 ? 
ATOM   3853 C CG   . TYR A 1 282 ? 9.333   18.074  10.635  1     16.395 ? 450 TYR A CG   1 ? 
ATOM   3854 C CD1  . TYR A 1 282 ? 9.66    19.408  10.348  1     17.055 ? 450 TYR A CD1  1 ? 
ATOM   3855 C CD2  . TYR A 1 282 ? 10.346  17.134  10.55   1     16.972 ? 450 TYR A CD2  1 ? 
ATOM   3856 C CE1  . TYR A 1 282 ? 10.957  19.781  10.024  1     17.449 ? 450 TYR A CE1  1 ? 
ATOM   3857 C CE2  . TYR A 1 282 ? 11.649  17.501  10.245  1     17.614 ? 450 TYR A CE2  1 ? 
ATOM   3858 C CZ   . TYR A 1 282 ? 11.951  18.819  9.972   1     16.55  ? 450 TYR A CZ   1 ? 
ATOM   3859 O OH   . TYR A 1 282 ? 13.244  19.168  9.7     1     18.025 ? 450 TYR A OH   1 ? 
ATOM   3860 H H    . TYR A 1 282 ? 5.116   17.278  10.743  1     15.267 ? 450 TYR A H    1 c 
ATOM   3861 H HA   . TYR A 1 282 ? 6.942   19.338  10.289  1     15.685 ? 450 TYR A HA   1 c 
ATOM   3862 H HB2  . TYR A 1 282 ? 7.824   17.84   12.011  1     16.281 ? 450 TYR A HB2  1 c 
ATOM   3863 H HB3  . TYR A 1 282 ? 7.834   16.69   10.922  1     16.285 ? 450 TYR A HB3  1 c 
ATOM   3864 H HD1  . TYR A 1 282 ? 8.995   20.073  10.407  1     16.98  ? 450 TYR A HD1  1 c 
ATOM   3865 H HD2  . TYR A 1 282 ? 10.159  16.233  10.76   1     16.978 ? 450 TYR A HD2  1 c 
ATOM   3866 H HE1  . TYR A 1 282 ? 11.163  20.684  9.856   1     17.154 ? 450 TYR A HE1  1 c 
ATOM   3867 H HE2  . TYR A 1 282 ? 12.327  16.848  10.21   1     17.21  ? 450 TYR A HE2  1 c 
ATOM   3868 N N    . VAL A 1 283 ? 7.34    18.548  7.973   1     14.825 ? 451 VAL A N    1 ? 
ATOM   3869 C CA   . VAL A 1 283 ? 7.474   18.046  6.617   1     16.121 ? 451 VAL A CA   1 ? 
ATOM   3870 C C    . VAL A 1 283 ? 8.948   18.078  6.253   1     15.492 ? 451 VAL A C    1 ? 
ATOM   3871 O O    . VAL A 1 283 ? 9.658   19.038  6.525   1     18.149 ? 451 VAL A O    1 ? 
ATOM   3872 C CB   . VAL A 1 283 ? 6.659   18.886  5.621   1     17.228 ? 451 VAL A CB   1 ? 
ATOM   3873 C CG1  . VAL A 1 283 ? 6.914   18.397  4.19    1     18.257 ? 451 VAL A CG1  1 ? 
ATOM   3874 C CG2  . VAL A 1 283 ? 5.186   18.85   5.967   1     17.113 ? 451 VAL A CG2  1 ? 
ATOM   3875 H H    . VAL A 1 283 ? 7.673   19.374  8.18    1     15.225 ? 451 VAL A H    1 c 
ATOM   3876 H HA   . VAL A 1 283 ? 7.158   17.13   6.585   1     15.952 ? 451 VAL A HA   1 c 
ATOM   3877 H HB   . VAL A 1 283 ? 6.976   19.815  5.69    1     17.2   ? 451 VAL A HB   1 c 
ATOM   3878 H HG11 . VAL A 1 283 ? 7.035   17.432  4.19    1     17.916 ? 451 VAL A HG11 1 c 
ATOM   3879 H HG12 . VAL A 1 283 ? 7.712   18.824  3.838   1     17.933 ? 451 VAL A HG12 1 c 
ATOM   3880 H HG13 . VAL A 1 283 ? 6.154   18.625  3.628   1     17.935 ? 451 VAL A HG13 1 c 
ATOM   3881 H HG21 . VAL A 1 283 ? 4.703   19.466  5.39    1     17.142 ? 451 VAL A HG21 1 c 
ATOM   3882 H HG22 . VAL A 1 283 ? 5.059   19.11   6.893   1     17.128 ? 451 VAL A HG22 1 c 
ATOM   3883 H HG23 . VAL A 1 283 ? 4.844   17.95   5.835   1     17.138 ? 451 VAL A HG23 1 c 
ATOM   3884 N N    . THR A 1 284 ? 9.432   16.994  5.659   1     17.123 ? 452 THR A N    1 ? 
ATOM   3885 C CA   . THR A 1 284 ? 10.852  16.88   5.426   1     16.606 ? 452 THR A CA   1 ? 
ATOM   3886 C C    . THR A 1 284 ? 11.04   15.922  4.25    1     17.222 ? 452 THR A C    1 ? 
ATOM   3887 O O    . THR A 1 284 ? 10.116  15.731  3.45    1     16.863 ? 452 THR A O    1 ? 
ATOM   3888 C CB   . THR A 1 284 ? 11.553  16.471  6.727   1     17.237 ? 452 THR A CB   1 ? 
ATOM   3889 O OG1  . THR A 1 284 ? 12.967  16.509  6.532   1     18.689 ? 452 THR A OG1  1 ? 
ATOM   3890 C CG2  . THR A 1 284 ? 11.146  15.106  7.232   1     16.919 ? 452 THR A CG2  1 ? 
ATOM   3891 H H    . THR A 1 284 ? 8.876   16.318  5.397   1     16.599 ? 452 THR A H    1 c 
ATOM   3892 H HA   . THR A 1 284 ? 11.196  17.76   5.157   1     16.932 ? 452 THR A HA   1 c 
ATOM   3893 H HB   . THR A 1 284 ? 11.32   17.125  7.428   1     17.328 ? 452 THR A HB   1 c 
ATOM   3894 H HG21 . THR A 1 284 ? 11.479  14.983  8.136   1     17.013 ? 452 THR A HG21 1 c 
ATOM   3895 H HG22 . THR A 1 284 ? 11.521  14.42   6.655   1     17.014 ? 452 THR A HG22 1 c 
ATOM   3896 H HG23 . THR A 1 284 ? 10.177  15.033  7.233   1     17.013 ? 452 THR A HG23 1 c 
ATOM   3897 N N    . VAL A 1 285 ? 12.269  15.428  4.152   1     17.175 ? 453 VAL A N    1 ? 
ATOM   3898 C CA   . VAL A 1 285 ? 12.712  14.537  3.102   1     20.082 ? 453 VAL A CA   1 ? 
ATOM   3899 C C    . VAL A 1 285 ? 12.789  13.113  3.634   1     19.215 ? 453 VAL A C    1 ? 
ATOM   3900 O O    . VAL A 1 285 ? 13.135  12.87   4.773   1     16.891 ? 453 VAL A O    1 ? 
ATOM   3901 C CB   . VAL A 1 285 ? 14.032  15.027  2.489   1     21.517 ? 453 VAL A CB   1 ? 
ATOM   3902 C CG1  . VAL A 1 285 ? 13.869  16.407  1.853   1     24.569 ? 453 VAL A CG1  1 ? 
ATOM   3903 C CG2  . VAL A 1 285 ? 15.189  15.017  3.477   1     23.726 ? 453 VAL A CG2  1 ? 
ATOM   3904 H H    . VAL A 1 285 ? 12.878  15.665  4.789   1     17.87  ? 453 VAL A H    1 c 
ATOM   3905 H HA   . VAL A 1 285 ? 12.039  14.553  2.394   1     19.568 ? 453 VAL A HA   1 c 
ATOM   3906 H HB   . VAL A 1 285 ? 14.262  14.397  1.765   1     22.177 ? 453 VAL A HB   1 c 
ATOM   3907 H HG11 . VAL A 1 285 ? 14.009  17.094  2.527   1     23.655 ? 453 VAL A HG11 1 c 
ATOM   3908 H HG12 . VAL A 1 285 ? 12.974  16.494  1.486   1     23.662 ? 453 VAL A HG12 1 c 
ATOM   3909 H HG13 . VAL A 1 285 ? 14.522  16.514  1.142   1     23.73  ? 453 VAL A HG13 1 c 
ATOM   3910 H HG21 . VAL A 1 285 ? 15.997  15.318  3.029   1     23.017 ? 453 VAL A HG21 1 c 
ATOM   3911 H HG22 . VAL A 1 285 ? 15.327  14.116  3.814   1     22.972 ? 453 VAL A HG22 1 c 
ATOM   3912 H HG23 . VAL A 1 285 ? 14.993  15.613  4.218   1     22.955 ? 453 VAL A HG23 1 c 
ATOM   3913 N N    . ARG A 1 286 ? 12.468  12.152  2.771   1     19.908 ? 454 ARG A N    1 ? 
ATOM   3914 C CA   . ARG A 1 286 ? 12.361  10.757  3.155   1     20.476 ? 454 ARG A CA   1 ? 
ATOM   3915 C C    . ARG A 1 286 ? 13.667  10.208  3.72    1     17.527 ? 454 ARG A C    1 ? 
ATOM   3916 O O    . ARG A 1 286 ? 13.665  9.289   4.546   1     18.782 ? 454 ARG A O    1 ? 
ATOM   3917 C CB   . ARG A 1 286 ? 11.958  10.042  1.853   1     25.181 ? 454 ARG A CB   1 ? 
ATOM   3918 C CG   . ARG A 1 286 ? 11.803  8.532   1.883   1     27.459 ? 454 ARG A CG   1 ? 
ATOM   3919 C CD   . ARG A 1 286 ? 10.51   8.201   2.548   1     27.621 ? 454 ARG A CD   1 ? 
ATOM   3920 N NE   . ARG A 1 286 ? 9.305   8.633   1.826   1     27.187 ? 454 ARG A NE   1 ? 
ATOM   3921 C CZ   . ARG A 1 286 ? 8.087   8.561   2.382   1     23.548 ? 454 ARG A CZ   1 ? 
ATOM   3922 N NH1  . ARG A 1 286 ? 7.887   7.812   3.436   1     21.157 ? 454 ARG A NH1  1 ? 
ATOM   3923 N NH2  . ARG A 1 286 ? 7.046   9.189   1.873   1     22.134 ? 454 ARG A NH2  1 ? 
ATOM   3924 H H    . ARG A 1 286 ? 12.313  12.38   1.899   1     19.969 ? 454 ARG A H    1 c 
ATOM   3925 H HA   . ARG A 1 286 ? 11.647  10.66   3.828   1     20.531 ? 454 ARG A HA   1 c 
ATOM   3926 H HB2  . ARG A 1 286 ? 11.111  10.432  1.549   1     24.502 ? 454 ARG A HB2  1 c 
ATOM   3927 H HB3  . ARG A 1 286 ? 12.631  10.261  1.176   1     24.441 ? 454 ARG A HB3  1 c 
ATOM   3928 H HG2  . ARG A 1 286 ? 11.8    8.18    0.967   1     26.944 ? 454 ARG A HG2  1 c 
ATOM   3929 H HG3  . ARG A 1 286 ? 12.544  8.123   2.38    1     26.857 ? 454 ARG A HG3  1 c 
ATOM   3930 H HD2  . ARG A 1 286 ? 10.471  7.23    2.672   1     27.452 ? 454 ARG A HD2  1 c 
ATOM   3931 H HD3  . ARG A 1 286 ? 10.507  8.607   3.439   1     27.326 ? 454 ARG A HD3  1 c 
ATOM   3932 H HE   . ARG A 1 286 ? 9.385   8.933   1.016   1     26.342 ? 454 ARG A HE   1 c 
ATOM   3933 H HH11 . ARG A 1 286 ? 8.123   6.96    3.423   1     21.889 ? 454 ARG A HH11 1 c 
ATOM   3934 H HH12 . ARG A 1 286 ? 7.507   8.158   4.155   1     21.847 ? 454 ARG A HH12 1 c 
ATOM   3935 H HH21 . ARG A 1 286 ? 7.153   9.978   1.49    1     22.501 ? 454 ARG A HH21 1 c 
ATOM   3936 H HH22 . ARG A 1 286 ? 6.246   8.816   1.914   1     22.516 ? 454 ARG A HH22 1 c 
ATOM   3937 N N    . ALA A 1 287 ? 14.791  10.754  3.295   1     17.798 ? 455 ALA A N    1 ? 
ATOM   3938 C CA   . ALA A 1 287 ? 16.081  10.29   3.753   1     20.724 ? 455 ALA A CA   1 ? 
ATOM   3939 C C    . ALA A 1 287 ? 16.321  10.627  5.23    1     19.243 ? 455 ALA A C    1 ? 
ATOM   3940 O O    . ALA A 1 287 ? 17.224  10.045  5.843   1     20.16  ? 455 ALA A O    1 ? 
ATOM   3941 C CB   . ALA A 1 287 ? 17.158  10.926  2.895   1     21.914 ? 455 ALA A CB   1 ? 
ATOM   3942 H H    . ALA A 1 287 ? 14.764  11.424  2.674   1     18.411 ? 455 ALA A H    1 c 
ATOM   3943 H HA   . ALA A 1 287 ? 16.118  9.299   3.645   1     20.029 ? 455 ALA A HA   1 c 
ATOM   3944 H HB1  . ALA A 1 287 ? 16.985  10.739  1.961   1     21.603 ? 455 ALA A HB1  1 c 
ATOM   3945 H HB2  . ALA A 1 287 ? 17.161  11.888  3.034   1     21.65  ? 455 ALA A HB2  1 c 
ATOM   3946 H HB3  . ALA A 1 287 ? 18.027  10.564  3.139   1     21.583 ? 455 ALA A HB3  1 c 
ATOM   3947 N N    . LEU A 1 288 ? 15.57   11.593  5.773   1     19.396 ? 456 LEU A N    1 ? 
ATOM   3948 C CA   . LEU A 1 288 ? 15.716  12.011  7.154   1     16.473 ? 456 LEU A CA   1 ? 
ATOM   3949 C C    . LEU A 1 288 ? 17.185  12.267  7.454   1     18.733 ? 456 LEU A C    1 ? 
ATOM   3950 O O    . LEU A 1 288 ? 17.704  11.822  8.491   1     18.023 ? 456 LEU A O    1 ? 
ATOM   3951 C CB   . LEU A 1 288 ? 15.13   10.934  8.075   1     17.894 ? 456 LEU A CB   1 ? 
ATOM   3952 C CG   . LEU A 1 288 ? 13.623  10.702  7.966   1     17.422 ? 456 LEU A CG   1 ? 
ATOM   3953 C CD1  . LEU A 1 288 ? 13.217  9.574   8.928   1     19.184 ? 456 LEU A CD1  1 ? 
ATOM   3954 C CD2  . LEU A 1 288 ? 12.866  11.992  8.312   1     18.495 ? 456 LEU A CD2  1 ? 
ATOM   3955 H H    . LEU A 1 288 ? 14.961  12.034  5.256   1     18.654 ? 456 LEU A H    1 c 
ATOM   3956 H HA   . LEU A 1 288 ? 15.219  12.858  7.278   1     17.696 ? 456 LEU A HA   1 c 
ATOM   3957 H HB2  . LEU A 1 288 ? 15.59   10.083  7.894   1     17.479 ? 456 LEU A HB2  1 c 
ATOM   3958 H HB3  . LEU A 1 288 ? 15.332  11.184  9.007   1     17.473 ? 456 LEU A HB3  1 c 
ATOM   3959 H HG   . LEU A 1 288 ? 13.405  10.434  7.036   1     18.017 ? 456 LEU A HG   1 c 
ATOM   3960 H HD11 . LEU A 1 288 ? 13.691  8.759   8.692   1     18.652 ? 456 LEU A HD11 1 c 
ATOM   3961 H HD12 . LEU A 1 288 ? 12.259  9.421   8.864   1     18.652 ? 456 LEU A HD12 1 c 
ATOM   3962 H HD13 . LEU A 1 288 ? 13.443  9.827   9.839   1     18.652 ? 456 LEU A HD13 1 c 
ATOM   3963 H HD21 . LEU A 1 288 ? 12.88   12.592  7.548   1     18.171 ? 456 LEU A HD21 1 c 
ATOM   3964 H HD22 . LEU A 1 288 ? 13.291  12.426  9.071   1     18.169 ? 456 LEU A HD22 1 c 
ATOM   3965 H HD23 . LEU A 1 288 ? 11.945  11.778  8.537   1     18.178 ? 456 LEU A HD23 1 c 
ATOM   3966 N N    . ASP A 1 289 ? 17.833  13.062  6.592   1     18.334 ? 457 ASP A N    1 ? 
ATOM   3967 C CA   . ASP A 1 289 ? 19.287  13.169  6.578   1     19.582 ? 457 ASP A CA   1 ? 
ATOM   3968 C C    . ASP A 1 289 ? 19.734  14.608  6.747   1     17.839 ? 457 ASP A C    1 ? 
ATOM   3969 O O    . ASP A 1 289 ? 20.873  14.929  6.406   1     21.442 ? 457 ASP A O    1 ? 
ATOM   3970 C CB   . ASP A 1 289 ? 19.871  12.567  5.304   1     19.113 ? 457 ASP A CB   1 ? 
ATOM   3971 C CG   . ASP A 1 289 ? 19.508  13.346  4.039   1     20.922 ? 457 ASP A CG   1 ? 
ATOM   3972 O OD1  . ASP A 1 289 ? 18.526  14.104  4.107   1     21.474 ? 457 ASP A OD1  1 ? 
ATOM   3973 O OD2  . ASP A 1 289 ? 20.26   13.274  3.039   1     22.727 ? 457 ASP A OD2  1 ? 
ATOM   3974 H H    . ASP A 1 289 ? 17.351  13.558  5.994   1     18.695 ? 457 ASP A H    1 c 
ATOM   3975 H HA   . ASP A 1 289 ? 19.647  12.648  7.327   1     18.911 ? 457 ASP A HA   1 c 
ATOM   3976 H HB2  . ASP A 1 289 ? 20.847  12.522  5.377   1     19.644 ? 457 ASP A HB2  1 c 
ATOM   3977 H HB3  . ASP A 1 289 ? 19.534  11.652  5.206   1     19.625 ? 457 ASP A HB3  1 c 
ATOM   3978 N N    . ARG A 1 290 ? 18.844  15.457  7.276   1     18.178 ? 458 ARG A N    1 ? 
ATOM   3979 C CA   . ARG A 1 290 ? 19.077  16.879  7.385   1     18.497 ? 458 ARG A CA   1 ? 
ATOM   3980 C C    . ARG A 1 290 ? 17.92   17.486  8.182   1     16.051 ? 458 ARG A C    1 ? 
ATOM   3981 O O    . ARG A 1 290 ? 16.871  16.856  8.379   1     18.787 ? 458 ARG A O    1 ? 
ATOM   3982 C CB   . ARG A 1 290 ? 19.182  17.543  5.992   1     19.434 ? 458 ARG A CB   1 ? 
ATOM   3983 C CG   . ARG A 1 290 ? 17.841  17.562  5.259   1     22.495 ? 458 ARG A CG   1 ? 
ATOM   3984 C CD   . ARG A 1 290 ? 17.958  17.804  3.732   1     24.848 ? 458 ARG A CD   1 ? 
ATOM   3985 N NE   . ARG A 1 290 ? 18.656  16.683  3.088   1     28.12  ? 458 ARG A NE   1 ? 
ATOM   3986 C CZ   . ARG A 1 290 ? 19.584  16.807  2.147   1     37.936 ? 458 ARG A CZ   1 ? 
ATOM   3987 N NH1  . ARG A 1 290 ? 19.809  17.999  1.619   1     38.323 ? 458 ARG A NH1  1 ? 
ATOM   3988 N NH2  . ARG A 1 290 ? 20.244  15.748  1.697   1     36.942 ? 458 ARG A NH2  1 ? 
ATOM   3989 H H    . ARG A 1 290 ? 18.059  15.125  7.605   1     18.167 ? 458 ARG A H    1 c 
ATOM   3990 H HA   . ARG A 1 290 ? 19.922  17.021  7.883   1     18.11  ? 458 ARG A HA   1 c 
ATOM   3991 H HB2  . ARG A 1 290 ? 19.497  18.465  6.103   1     19.803 ? 458 ARG A HB2  1 c 
ATOM   3992 H HB3  . ARG A 1 290 ? 19.841  17.065  5.446   1     19.894 ? 458 ARG A HB3  1 c 
ATOM   3993 H HG2  . ARG A 1 290 ? 17.383  16.706  5.408   1     22.187 ? 458 ARG A HG2  1 c 
ATOM   3994 H HG3  . ARG A 1 290 ? 17.277  18.268  5.643   1     22.203 ? 458 ARG A HG3  1 c 
ATOM   3995 H HD2  . ARG A 1 290 ? 17.066  17.898  3.342   1     25.018 ? 458 ARG A HD2  1 c 
ATOM   3996 H HD3  . ARG A 1 290 ? 18.45   18.631  3.58    1     24.873 ? 458 ARG A HD3  1 c 
ATOM   3997 H HE   . ARG A 1 290 ? 18.441  15.879  3.338   1     29.395 ? 458 ARG A HE   1 c 
ATOM   3998 H HH11 . ARG A 1 290 ? 19.138  18.481  1.306   1     37.874 ? 458 ARG A HH11 1 c 
ATOM   3999 H HH12 . ARG A 1 290 ? 20.637  18.299  1.564   1     37.731 ? 458 ARG A HH12 1 c 
ATOM   4000 H HH21 . ARG A 1 290 ? 19.82   14.98   1.591   1     37.175 ? 458 ARG A HH21 1 c 
ATOM   4001 H HH22 . ARG A 1 290 ? 21.104  15.816  1.506   1     37.228 ? 458 ARG A HH22 1 c 
ATOM   4002 N N    . VAL A 1 291 ? 18.155  18.702  8.689   1     16.68  ? 459 VAL A N    1 ? 
ATOM   4003 C CA   . VAL A 1 291 ? 17.132  19.478  9.373   1     15.91  ? 459 VAL A CA   1 ? 
ATOM   4004 C C    . VAL A 1 291 ? 16.391  20.353  8.367   1     18.134 ? 459 VAL A C    1 ? 
ATOM   4005 O O    . VAL A 1 291 ? 16.822  21.467  8.09    1     19.778 ? 459 VAL A O    1 ? 
ATOM   4006 C CB   . VAL A 1 291 ? 17.757  20.342  10.479  1     18.435 ? 459 VAL A CB   1 ? 
ATOM   4007 C CG1  . VAL A 1 291 ? 16.71   21.147  11.23   1     17.599 ? 459 VAL A CG1  1 ? 
ATOM   4008 C CG2  . VAL A 1 291 ? 18.536  19.471  11.44   1     19.64  ? 459 VAL A CG2  1 ? 
ATOM   4009 H H    . VAL A 1 291 ? 18.99   19.064  8.604   1     16.392 ? 459 VAL A H    1 c 
ATOM   4010 H HA   . VAL A 1 291 ? 16.494  18.866  9.787   1     16.902 ? 459 VAL A HA   1 c 
ATOM   4011 H HB   . VAL A 1 291 ? 18.388  20.968  10.051  1     18.007 ? 459 VAL A HB   1 c 
ATOM   4012 H HG11 . VAL A 1 291 ? 15.908  20.61   11.343  1     17.837 ? 459 VAL A HG11 1 c 
ATOM   4013 H HG12 . VAL A 1 291 ? 16.493  21.949  10.725  1     17.855 ? 459 VAL A HG12 1 c 
ATOM   4014 H HG13 . VAL A 1 291 ? 17.053  21.401  12.103  1     17.862 ? 459 VAL A HG13 1 c 
ATOM   4015 H HG21 . VAL A 1 291 ? 18.803  19.994  12.214  1     19.25  ? 459 VAL A HG21 1 c 
ATOM   4016 H HG22 . VAL A 1 291 ? 19.329  19.126  10.998  1     19.254 ? 459 VAL A HG22 1 c 
ATOM   4017 H HG23 . VAL A 1 291 ? 17.978  18.729  11.729  1     19.266 ? 459 VAL A HG23 1 c 
ATOM   4018 N N    . THR A 1 292 ? 15.301  19.837  7.802   1     16.409 ? 460 THR A N    1 ? 
ATOM   4019 C CA   . THR A 1 292 ? 14.472  20.663  6.934   1     15.538 ? 460 THR A CA   1 ? 
ATOM   4020 C C    . THR A 1 292 ? 13.87   21.803  7.753   1     18.937 ? 460 THR A C    1 ? 
ATOM   4021 O O    . THR A 1 292 ? 13.431  21.62   8.87    1     18.443 ? 460 THR A O    1 ? 
ATOM   4022 C CB   . THR A 1 292 ? 13.377  19.83   6.281   1     15.489 ? 460 THR A CB   1 ? 
ATOM   4023 O OG1  . THR A 1 292 ? 14.062  18.835  5.528   1     17.21  ? 460 THR A OG1  1 ? 
ATOM   4024 C CG2  . THR A 1 292 ? 12.479  20.631  5.377   1     18.566 ? 460 THR A CG2  1 ? 
ATOM   4025 H H    . THR A 1 292 ? 15.069  18.966  7.951   1     16.592 ? 460 THR A H    1 c 
ATOM   4026 H HA   . THR A 1 292 ? 15.039  21.038  6.228   1     16.275 ? 460 THR A HA   1 c 
ATOM   4027 H HB   . THR A 1 292 ? 12.831  19.395  6.978   1     16.36  ? 460 THR A HB   1 c 
ATOM   4028 H HG21 . THR A 1 292 ? 12.094  20.047  4.701   1     17.584 ? 460 THR A HG21 1 c 
ATOM   4029 H HG22 . THR A 1 292 ? 12.995  21.331  4.942   1     17.577 ? 460 THR A HG22 1 c 
ATOM   4030 H HG23 . THR A 1 292 ? 11.765  21.033  5.9     1     17.591 ? 460 THR A HG23 1 c 
ATOM   4031 N N    . VAL A 1 293 ? 13.831  22.985  7.145   1     17.194 ? 461 VAL A N    1 ? 
ATOM   4032 C CA   . VAL A 1 293 ? 13.162  24.129  7.708   1     19.244 ? 461 VAL A CA   1 ? 
ATOM   4033 C C    . VAL A 1 293 ? 12.265  24.659  6.596   1     19.976 ? 461 VAL A C    1 ? 
ATOM   4034 O O    . VAL A 1 293 ? 12.764  25.079  5.55    1     19.341 ? 461 VAL A O    1 ? 
ATOM   4035 C CB   . VAL A 1 293 ? 14.142  25.209  8.19    1     21.13  ? 461 VAL A CB   1 ? 
ATOM   4036 C CG1  . VAL A 1 293 ? 13.404  26.474  8.602   1     23.177 ? 461 VAL A CG1  1 ? 
ATOM   4037 C CG2  . VAL A 1 293 ? 15.075  24.734  9.302   1     20.842 ? 461 VAL A CG2  1 ? 
ATOM   4038 H H    . VAL A 1 293 ? 14.251  23.083  6.339   1     18.028 ? 461 VAL A H    1 c 
ATOM   4039 H HA   . VAL A 1 293 ? 12.609  23.844  8.461   1     19.254 ? 461 VAL A HA   1 c 
ATOM   4040 H HB   . VAL A 1 293 ? 14.708  25.44   7.419   1     21     ? 461 VAL A HB   1 c 
ATOM   4041 H HG11 . VAL A 1 293 ? 12.556  26.237  9.014   1     22.511 ? 461 VAL A HG11 1 c 
ATOM   4042 H HG12 . VAL A 1 293 ? 13.241  27.026  7.819   1     22.527 ? 461 VAL A HG12 1 c 
ATOM   4043 H HG13 . VAL A 1 293 ? 13.943  26.973  9.239   1     22.52  ? 461 VAL A HG13 1 c 
ATOM   4044 H HG21 . VAL A 1 293 ? 15.717  25.434  9.509   1     20.931 ? 461 VAL A HG21 1 c 
ATOM   4045 H HG22 . VAL A 1 293 ? 15.549  23.937  9.011   1     20.907 ? 461 VAL A HG22 1 c 
ATOM   4046 H HG23 . VAL A 1 293 ? 14.554  24.528  10.097  1     20.923 ? 461 VAL A HG23 1 c 
ATOM   4047 N N    . ASN A 1 294 ? 10.962  24.623  6.843   1     17.439 ? 462 ASN A N    1 ? 
ATOM   4048 C CA   . ASN A 1 294 ? 9.966   25.103  5.897   1     18.984 ? 462 ASN A CA   1 ? 
ATOM   4049 C C    . ASN A 1 294 ? 9.569   26.515  6.32    1     19.611 ? 462 ASN A C    1 ? 
ATOM   4050 O O    . ASN A 1 294 ? 8.805   26.72   7.253   1     20.347 ? 462 ASN A O    1 ? 
ATOM   4051 C CB   . ASN A 1 294 ? 8.769   24.17   5.835   1     16.894 ? 462 ASN A CB   1 ? 
ATOM   4052 C CG   . ASN A 1 294 ? 9.118   22.761  5.435   1     18.953 ? 462 ASN A CG   1 ? 
ATOM   4053 O OD1  . ASN A 1 294 ? 9.365   22.483  4.246   1     18.79  ? 462 ASN A OD1  1 ? 
ATOM   4054 N ND2  . ASN A 1 294 ? 9.112   21.845  6.41    1     19.735 ? 462 ASN A ND2  1 ? 
ATOM   4055 H H    . ASN A 1 294 ? 10.67   24.28   7.638   1     18.374 ? 462 ASN A H    1 c 
ATOM   4056 H HA   . ASN A 1 294 ? 10.365  25.133  4.999   1     18.435 ? 462 ASN A HA   1 c 
ATOM   4057 H HB2  . ASN A 1 294 ? 8.335   24.151  6.711   1     17.853 ? 462 ASN A HB2  1 c 
ATOM   4058 H HB3  . ASN A 1 294 ? 8.124   24.527  5.192   1     17.823 ? 462 ASN A HB3  1 c 
ATOM   4059 H HD21 . ASN A 1 294 ? 8.926   21      6.219   1     19.439 ? 462 ASN A HD21 1 c 
ATOM   4060 H HD22 . ASN A 1 294 ? 9.3     22.08   7.244   1     19.448 ? 462 ASN A HD22 1 c 
ATOM   4061 N N    . ALA A 1 295 ? 10.091  27.514  5.601   1     21.909 ? 463 ALA A N    1 ? 
ATOM   4062 C CA   . ALA A 1 295 ? 9.885   28.899  5.999   1     24.058 ? 463 ALA A CA   1 ? 
ATOM   4063 C C    . ALA A 1 295 ? 8.391   29.218  6.052   1     21.853 ? 463 ALA A C    1 ? 
ATOM   4064 O O    . ALA A 1 295 ? 7.632   28.927  5.121   1     24.331 ? 463 ALA A O    1 ? 
ATOM   4065 C CB   . ALA A 1 295 ? 10.605  29.82   5.008   1     26.155 ? 463 ALA A CB   1 ? 
ATOM   4066 H H    . ALA A 1 295 ? 10.582  27.333  4.852   1     21.79  ? 463 ALA A H    1 c 
ATOM   4067 H HA   . ALA A 1 295 ? 10.273  29.024  6.907   1     23.582 ? 463 ALA A HA   1 c 
ATOM   4068 H HB1  . ALA A 1 295 ? 11.566  29.707  5.097   1     25.313 ? 463 ALA A HB1  1 c 
ATOM   4069 H HB2  . ALA A 1 295 ? 10.339  29.596  4.101   1     25.306 ? 463 ALA A HB2  1 c 
ATOM   4070 H HB3  . ALA A 1 295 ? 10.373  30.743  5.192   1     25.291 ? 463 ALA A HB3  1 c 
ATOM   4071 N N    . GLY A 1 296 ? 7.967   29.823  7.168   1     22.391 ? 464 GLY A N    1 ? 
ATOM   4072 C CA   . GLY A 1 296 ? 6.568   30.162  7.34    1     25.18  ? 464 GLY A CA   1 ? 
ATOM   4073 C C    . GLY A 1 296 ? 5.792   29.094  8.096   1     24.835 ? 464 GLY A C    1 ? 
ATOM   4074 O O    . GLY A 1 296 ? 4.686   29.379  8.542   1     28.092 ? 464 GLY A O    1 ? 
ATOM   4075 H H    . GLY A 1 296 ? 8.558   30.031  7.832   1     22.875 ? 464 GLY A H    1 c 
ATOM   4076 H HA2  . GLY A 1 296 ? 6.51    31.012  7.835   1     24.406 ? 464 GLY A HA2  1 c 
ATOM   4077 H HA3  . GLY A 1 296 ? 6.153   30.304  6.457   1     24.394 ? 464 GLY A HA3  1 c 
ATOM   4078 N N    . TRP A 1 297 ? 6.364   27.885  8.22    1     20.938 ? 465 TRP A N    1 ? 
ATOM   4079 C CA   . TRP A 1 297 ? 5.689   26.774  8.849   1     17.872 ? 465 TRP A CA   1 ? 
ATOM   4080 C C    . TRP A 1 297 ? 6.439   26.339  10.09   1     18.283 ? 465 TRP A C    1 ? 
ATOM   4081 O O    . TRP A 1 297 ? 5.788   26.013  11.093  1     21.018 ? 465 TRP A O    1 ? 
ATOM   4082 C CB   . TRP A 1 297 ? 5.535   25.591  7.866   1     18.143 ? 465 TRP A CB   1 ? 
ATOM   4083 C CG   . TRP A 1 297 ? 4.72    25.995  6.674   1     20.121 ? 465 TRP A CG   1 ? 
ATOM   4084 C CD1  . TRP A 1 297 ? 5.141   26.269  5.404   1     21.753 ? 465 TRP A CD1  1 ? 
ATOM   4085 C CD2  . TRP A 1 297 ? 3.303   26.244  6.7     1     20.023 ? 465 TRP A CD2  1 ? 
ATOM   4086 N NE1  . TRP A 1 297 ? 4.077   26.689  4.641   1     22.258 ? 465 TRP A NE1  1 ? 
ATOM   4087 C CE2  . TRP A 1 297 ? 2.941   26.678  5.402   1     21.247 ? 465 TRP A CE2  1 ? 
ATOM   4088 C CE3  . TRP A 1 297 ? 2.327   26.172  7.686   1     20.399 ? 465 TRP A CE3  1 ? 
ATOM   4089 C CZ2  . TRP A 1 297 ? 1.619   26.988  5.079   1     22.567 ? 465 TRP A CZ2  1 ? 
ATOM   4090 C CZ3  . TRP A 1 297 ? 1.019   26.459  7.36    1     23.86  ? 465 TRP A CZ3  1 ? 
ATOM   4091 C CH2  . TRP A 1 297 ? 0.674   26.848  6.07    1     22.624 ? 465 TRP A CH2  1 ? 
ATOM   4092 H H    . TRP A 1 297 ? 7.192   27.743  7.864   1     21.008 ? 465 TRP A H    1 c 
ATOM   4093 H HA   . TRP A 1 297 ? 4.779   27.064  9.121   1     18.656 ? 465 TRP A HA   1 c 
ATOM   4094 H HB2  . TRP A 1 297 ? 6.425   25.306  7.568   1     18.514 ? 465 TRP A HB2  1 c 
ATOM   4095 H HB3  . TRP A 1 297 ? 5.089   24.849  8.327   1     18.505 ? 465 TRP A HB3  1 c 
ATOM   4096 H HD1  . TRP A 1 297 ? 6.031   26.211  5.095   1     21.458 ? 465 TRP A HD1  1 c 
ATOM   4097 H HE1  . TRP A 1 297 ? 4.115   26.89   3.792   1     21.869 ? 465 TRP A HE1  1 c 
ATOM   4098 H HE3  . TRP A 1 297 ? 2.548   25.871  8.548   1     21.133 ? 465 TRP A HE3  1 c 
ATOM   4099 H HZ2  . TRP A 1 297 ? 1.382   27.265  4.211   1     22.241 ? 465 TRP A HZ2  1 c 
ATOM   4100 H HZ3  . TRP A 1 297 ? 0.349   26.392  8.021   1     22.684 ? 465 TRP A HZ3  1 c 
ATOM   4101 H HH2  . TRP A 1 297 ? -0.219  27.076  5.884   1     22.846 ? 465 TRP A HH2  1 c 
ATOM   4102 N N    . ASP A 1 298 ? 7.78    26.352  10.014  1     17.026 ? 466 ASP A N    1 ? 
ATOM   4103 C CA   . ASP A 1 298 ? 8.613   25.932  11.125  1     18.339 ? 466 ASP A CA   1 ? 
ATOM   4104 C C    . ASP A 1 298 ? 9.139   27.174  11.839  1     20.543 ? 466 ASP A C    1 ? 
ATOM   4105 O O    . ASP A 1 298 ? 9.229   28.249  11.223  1     21.015 ? 466 ASP A O    1 ? 
ATOM   4106 C CB   . ASP A 1 298 ? 9.745   25.051  10.642  1     17.476 ? 466 ASP A CB   1 ? 
ATOM   4107 C CG   . ASP A 1 298 ? 9.282   23.749  10.022  1     18.019 ? 466 ASP A CG   1 ? 
ATOM   4108 O OD1  . ASP A 1 298 ? 8.279   23.163  10.539  1     18.639 ? 466 ASP A OD1  1 ? 
ATOM   4109 O OD2  . ASP A 1 298 ? 9.896   23.351  9.038   1     17.264 ? 466 ASP A OD2  1 ? 
ATOM   4110 H H    . ASP A 1 298 ? 8.19    26.603  9.238   1     17.667 ? 466 ASP A H    1 c 
ATOM   4111 H HA   . ASP A 1 298 ? 8.064   25.416  11.748  1     18.376 ? 466 ASP A HA   1 c 
ATOM   4112 H HB2  . ASP A 1 298 ? 10.26   25.547  9.972   1     17.801 ? 466 ASP A HB2  1 c 
ATOM   4113 H HB3  . ASP A 1 298 ? 10.345  24.84   11.385  1     17.844 ? 466 ASP A HB3  1 c 
ATOM   4114 N N    . PRO A 1 299 ? 9.54    27.043  13.12   1     21.684 ? 467 PRO A N    1 ? 
ATOM   4115 C CA   . PRO A 1 299 ? 10.01   28.193  13.899  1     23.633 ? 467 PRO A CA   1 ? 
ATOM   4116 C C    . PRO A 1 299 ? 11.332  28.674  13.307  1     27.779 ? 467 PRO A C    1 ? 
ATOM   4117 O O    . PRO A 1 299 ? 12.14   27.87   12.878  1     28.278 ? 467 PRO A O    1 ? 
ATOM   4118 C CB   . PRO A 1 299 ? 10.175  27.698  15.351  1     23.899 ? 467 PRO A CB   1 ? 
ATOM   4119 C CG   . PRO A 1 299 ? 9.84    26.239  15.338  1     25.968 ? 467 PRO A CG   1 ? 
ATOM   4120 C CD   . PRO A 1 299 ? 9.544   25.792  13.918  1     22.213 ? 467 PRO A CD   1 ? 
ATOM   4121 H HA   . PRO A 1 299 ? 9.333   28.915  13.863  1     24.043 ? 467 PRO A HA   1 c 
ATOM   4122 H HB2  . PRO A 1 299 ? 11.099  27.838  15.666  1     24.319 ? 467 PRO A HB2  1 c 
ATOM   4123 H HB3  . PRO A 1 299 ? 9.568   28.188  15.954  1     24.303 ? 467 PRO A HB3  1 c 
ATOM   4124 H HG2  . PRO A 1 299 ? 10.59   25.722  15.698  1     24.591 ? 467 PRO A HG2  1 c 
ATOM   4125 H HG3  . PRO A 1 299 ? 9.059   26.072  15.907  1     24.591 ? 467 PRO A HG3  1 c 
ATOM   4126 H HD2  . PRO A 1 299 ? 10.238  25.175  13.599  1     22.839 ? 467 PRO A HD2  1 c 
ATOM   4127 H HD3  . PRO A 1 299 ? 8.677   25.339  13.873  1     22.878 ? 467 PRO A HD3  1 c 
ATOM   4128 N N    . GLN A 1 300 ? 11.547  29.99   13.295  1     33.954 ? 468 GLN A N    1 ? 
ATOM   4129 C CA   . GLN A 1 300 ? 12.834  30.542  12.885  1     42.357 ? 468 GLN A CA   1 ? 
ATOM   4130 C C    . GLN A 1 300 ? 13.214  31.766  13.739  1     42.674 ? 468 GLN A C    1 ? 
ATOM   4131 O O    . GLN A 1 300 ? 12.287  32.376  14.264  1     41.3   ? 468 GLN A O    1 ? 
ATOM   4132 C CB   . GLN A 1 300 ? 12.773  30.965  11.419  1     42.565 ? 468 GLN A CB   1 ? 
ATOM   4133 C CG   . GLN A 1 300 ? 12.992  29.808  10.455  1     39.442 ? 468 GLN A CG   1 ? 
ATOM   4134 C CD   . GLN A 1 300 ? 12.912  30.254  9.008   1     31.517 ? 468 GLN A CD   1 ? 
ATOM   4135 O OE1  . GLN A 1 300 ? 11.83   30.486  8.495   1     30.137 ? 468 GLN A OE1  1 ? 
ATOM   4136 N NE2  . GLN A 1 300 ? 14.048  30.346  8.328   1     35.938 ? 468 GLN A NE2  1 ? 
ATOM   4137 O OXT  . GLN A 1 300 ? 14.442  32.065  13.805  1     51.352 ? 468 GLN A OXT  1 ? 
ATOM   4138 H H    . GLN A 1 300 ? 10.88   30.562  13.546  1     33.882 ? 468 GLN A H    1 c 
ATOM   4139 H HA   . GLN A 1 300 ? 13.534  29.851  12.997  1     40.485 ? 468 GLN A HA   1 c 
ATOM   4140 H HB2  . GLN A 1 300 ? 11.897  31.367  11.241  1     41.7   ? 468 GLN A HB2  1 c 
ATOM   4141 H HB3  . GLN A 1 300 ? 13.455  31.649  11.254  1     41.603 ? 468 GLN A HB3  1 c 
ATOM   4142 H HG2  . GLN A 1 300 ? 13.866  29.402  10.624  1     38.086 ? 468 GLN A HG2  1 c 
ATOM   4143 H HG3  . GLN A 1 300 ? 12.308  29.123  10.608  1     37.99  ? 468 GLN A HG3  1 c 
ATOM   4144 H HE21 . GLN A 1 300 ? 14.052  30.204  7.453   1     34.195 ? 468 GLN A HE21 1 c 
ATOM   4145 H HE22 . GLN A 1 300 ? 14.802  30.551  8.75    1     34.494 ? 468 GLN A HE22 1 c 
ATOM   4146 N N    . GLN B 1 29  ? 31.91   41.417  11.671  0.33  31.625 ? 197 GLN D N    1 ? 
ATOM   4147 C CA   . GLN B 1 29  ? 31.205  41.095  10.402  0.33  28.885 ? 197 GLN D CA   1 ? 
ATOM   4148 C C    . GLN B 1 29  ? 32.054  40.13   9.582   0.33  26.362 ? 197 GLN D C    1 ? 
ATOM   4149 O O    . GLN B 1 29  ? 33.273  40.251  9.533   0.33  29.575 ? 197 GLN D O    1 ? 
ATOM   4150 C CB   . GLN B 1 29  ? 30.918  42.325  9.534   0.33  27.337 ? 197 GLN D CB   1 ? 
ATOM   4151 C CG   . GLN B 1 29  ? 29.806  43.231  10.051  0.33  27.869 ? 197 GLN D CG   1 ? 
ATOM   4152 C CD   . GLN B 1 29  ? 29.327  44.244  9.034   0.33  27.179 ? 197 GLN D CD   1 ? 
ATOM   4153 O OE1  . GLN B 1 29  ? 29.861  45.348  8.913   0.33  29.332 ? 197 GLN D OE1  1 ? 
ATOM   4154 N NE2  . GLN B 1 29  ? 28.261  43.894  8.336   0.33  26.755 ? 197 GLN D NE2  1 ? 
ATOM   4155 H H    . GLN B 1 29  ? 31.413  41.987  12.163  0.33  30.755 ? 197 GLN D H    1 c 
ATOM   4156 H HA   . GLN B 1 29  ? 30.347  40.652  10.626  0.33  28.611 ? 197 GLN D HA   1 c 
ATOM   4157 H HB2  . GLN B 1 29  ? 31.742  42.851  9.46    0.33  27.804 ? 197 GLN D HB2  1 c 
ATOM   4158 H HB3  . GLN B 1 29  ? 30.682  42.02   8.633   0.33  27.804 ? 197 GLN D HB3  1 c 
ATOM   4159 H HG2  . GLN B 1 29  ? 29.043  42.678  10.325  0.33  27.588 ? 197 GLN D HG2  1 c 
ATOM   4160 H HG3  . GLN B 1 29  ? 30.125  43.711  10.844  0.33  27.588 ? 197 GLN D HG3  1 c 
ATOM   4161 H HE21 . GLN B 1 29  ? 27.923  44.452  7.735   0.33  26.885 ? 197 GLN D HE21 1 c 
ATOM   4162 H HE22 . GLN B 1 29  ? 27.885  43.101  8.469   0.33  26.885 ? 197 GLN D HE22 1 c 
ATOM   4163 N N    . VAL B 1 30  ? 31.389  39.194  8.902   0.33  24.405 ? 198 VAL D N    1 ? 
ATOM   4164 C CA   . VAL B 1 30  ? 32.018  38.448  7.829   0.33  23.138 ? 198 VAL D CA   1 ? 
ATOM   4165 C C    . VAL B 1 30  ? 32.48   39.455  6.779   0.33  24.423 ? 198 VAL D C    1 ? 
ATOM   4166 O O    . VAL B 1 30  ? 31.682  40.24   6.268   0.33  23.501 ? 198 VAL D O    1 ? 
ATOM   4167 C CB   . VAL B 1 30  ? 31.072  37.424  7.174   0.33  23.436 ? 198 VAL D CB   1 ? 
ATOM   4168 C CG1  . VAL B 1 30  ? 31.737  36.702  6.009   0.33  23.19  ? 198 VAL D CG1  1 ? 
ATOM   4169 C CG2  . VAL B 1 30  ? 30.473  36.439  8.172   0.33  23.201 ? 198 VAL D CG2  1 ? 
ATOM   4170 H H    . VAL B 1 30  ? 30.518  39.017  9.113   0.33  24.561 ? 198 VAL D H    1 c 
ATOM   4171 H HA   . VAL B 1 30  ? 32.798  37.979  8.186   0.33  23.668 ? 198 VAL D HA   1 c 
ATOM   4172 H HB   . VAL B 1 30  ? 30.32   37.937  6.797   0.33  23.29  ? 198 VAL D HB   1 c 
ATOM   4173 H HG11 . VAL B 1 30  ? 32.523  36.227  6.327   0.33  23.262 ? 198 VAL D HG11 1 c 
ATOM   4174 H HG12 . VAL B 1 30  ? 32.002  37.349  5.334   0.33  23.262 ? 198 VAL D HG12 1 c 
ATOM   4175 H HG13 . VAL B 1 30  ? 31.112  36.067  5.62    0.33  23.262 ? 198 VAL D HG13 1 c 
ATOM   4176 H HG21 . VAL B 1 30  ? 29.889  35.818  7.705   0.33  23.27  ? 198 VAL D HG21 1 c 
ATOM   4177 H HG22 . VAL B 1 30  ? 29.96   36.924  8.84    0.33  23.27  ? 198 VAL D HG22 1 c 
ATOM   4178 H HG23 . VAL B 1 30  ? 31.187  35.945  8.609   0.33  23.27  ? 198 VAL D HG23 1 c 
ATOM   4179 N N    . PRO B 1 31  ? 33.773  39.445  6.402   0.33  24.88  ? 199 PRO D N    1 ? 
ATOM   4180 C CA   . PRO B 1 31  ? 34.263  40.304  5.328   0.33  25.071 ? 199 PRO D CA   1 ? 
ATOM   4181 C C    . PRO B 1 31  ? 33.54   40.033  4.015   0.33  24.789 ? 199 PRO D C    1 ? 
ATOM   4182 O O    . PRO B 1 31  ? 33.15   38.901  3.739   0.33  22.686 ? 199 PRO D O    1 ? 
ATOM   4183 C CB   . PRO B 1 31  ? 35.754  39.965  5.224   0.33  24.367 ? 199 PRO D CB   1 ? 
ATOM   4184 C CG   . PRO B 1 31  ? 36.092  39.324  6.545   0.33  23.926 ? 199 PRO D CG   1 ? 
ATOM   4185 C CD   . PRO B 1 31  ? 34.831  38.634  7.013   0.33  24.515 ? 199 PRO D CD   1 ? 
ATOM   4186 H HA   . PRO B 1 31  ? 34.151  41.253  5.589   0.33  24.854 ? 199 PRO D HA   1 c 
ATOM   4187 H HB2  . PRO B 1 31  ? 35.92   39.342  4.478   0.33  24.421 ? 199 PRO D HB2  1 c 
ATOM   4188 H HB3  . PRO B 1 31  ? 36.289  40.781  5.082   0.33  24.421 ? 199 PRO D HB3  1 c 
ATOM   4189 H HG2  . PRO B 1 31  ? 36.818  38.675  6.437   0.33  24.159 ? 199 PRO D HG2  1 c 
ATOM   4190 H HG3  . PRO B 1 31  ? 36.374  40.001  7.195   0.33  24.159 ? 199 PRO D HG3  1 c 
ATOM   4191 H HD2  . PRO B 1 31  ? 34.796  37.705  6.695   0.33  24.466 ? 199 PRO D HD2  1 c 
ATOM   4192 H HD3  . PRO B 1 31  ? 34.764  38.644  7.994   0.33  24.466 ? 199 PRO D HD3  1 c 
ATOM   4193 N N    . TRP B 1 32  ? 33.4    41.097  3.218   0.33  22.961 ? 200 TRP D N    1 ? 
ATOM   4194 C CA   . TRP B 1 32  ? 32.841  41.027  1.882   0.33  22.622 ? 200 TRP D CA   1 ? 
ATOM   4195 C C    . TRP B 1 32  ? 33.475  39.892  1.081   0.33  22.997 ? 200 TRP D C    1 ? 
ATOM   4196 O O    . TRP B 1 32  ? 32.776  39.128  0.424   0.33  23.723 ? 200 TRP D O    1 ? 
ATOM   4197 C CB   . TRP B 1 32  ? 33.066  42.383  1.202   0.33  21.515 ? 200 TRP D CB   1 ? 
ATOM   4198 C CG   . TRP B 1 32  ? 32.352  42.547  -0.107  0.33  20.673 ? 200 TRP D CG   1 ? 
ATOM   4199 C CD1  . TRP B 1 32  ? 32.908  42.548  -1.346  0.33  19.528 ? 200 TRP D CD1  1 ? 
ATOM   4200 C CD2  . TRP B 1 32  ? 30.936  42.742  -0.293  0.33  19.111 ? 200 TRP D CD2  1 ? 
ATOM   4201 N NE1  . TRP B 1 32  ? 31.945  42.725  -2.293  0.33  20.6   ? 200 TRP D NE1  1 ? 
ATOM   4202 C CE2  . TRP B 1 32  ? 30.727  42.844  -1.685  0.33  19.386 ? 200 TRP D CE2  1 ? 
ATOM   4203 C CE3  . TRP B 1 32  ? 29.84   42.838  0.562   0.33  18.331 ? 200 TRP D CE3  1 ? 
ATOM   4204 C CZ2  . TRP B 1 32  ? 29.465  43.037  -2.233  0.33  19.617 ? 200 TRP D CZ2  1 ? 
ATOM   4205 C CZ3  . TRP B 1 32  ? 28.589  43.037  0.019   0.33  18.056 ? 200 TRP D CZ3  1 ? 
ATOM   4206 C CH2  . TRP B 1 32  ? 28.404  43.116  -1.359  0.33  18.945 ? 200 TRP D CH2  1 ? 
ATOM   4207 H H    . TRP B 1 32  ? 33.67   41.912  3.53    0.33  23.304 ? 200 TRP D H    1 c 
ATOM   4208 H HA   . TRP B 1 32  ? 31.862  40.865  1.955   0.33  22.55  ? 200 TRP D HA   1 c 
ATOM   4209 H HB2  . TRP B 1 32  ? 32.771  43.091  1.814   0.33  21.56  ? 200 TRP D HB2  1 c 
ATOM   4210 H HB3  . TRP B 1 32  ? 34.029  42.5    1.053   0.33  21.56  ? 200 TRP D HB3  1 c 
ATOM   4211 H HD1  . TRP B 1 32  ? 33.826  42.439  -1.534  0.33  20.024 ? 200 TRP D HD1  1 c 
ATOM   4212 H HE1  . TRP B 1 32  ? 32.085  42.753  -3.154  0.33  20.049 ? 200 TRP D HE1  1 c 
ATOM   4213 H HE3  . TRP B 1 32  ? 29.954  42.774  1.495   0.33  18.469 ? 200 TRP D HE3  1 c 
ATOM   4214 H HZ2  . TRP B 1 32  ? 29.34   43.102  -3.164  0.33  19.397 ? 200 TRP D HZ2  1 c 
ATOM   4215 H HZ3  . TRP B 1 32  ? 27.84   43.094  0.589   0.33  18.35  ? 200 TRP D HZ3  1 c 
ATOM   4216 H HH2  . TRP B 1 32  ? 27.538  43.255  -1.699  0.33  18.894 ? 200 TRP D HH2  1 c 
ATOM   4217 N N    . SER B 1 33  ? 34.805  39.767  1.175   0.33  23.597 ? 201 SER D N    1 ? 
ATOM   4218 C CA   . SER B 1 33  ? 35.551  38.792  0.393   0.33  25.176 ? 201 SER D CA   1 ? 
ATOM   4219 C C    . SER B 1 33  ? 35.307  37.357  0.869   0.33  24.255 ? 201 SER D C    1 ? 
ATOM   4220 O O    . SER B 1 33  ? 35.678  36.425  0.17    0.33  25.888 ? 201 SER D O    1 ? 
ATOM   4221 C CB   . SER B 1 33  ? 37.028  39.101  0.428   0.33  25.311 ? 201 SER D CB   1 ? 
ATOM   4222 O OG   . SER B 1 33  ? 37.487  39.057  1.767   0.33  25.203 ? 201 SER D OG   1 ? 
ATOM   4223 H H    . SER B 1 33  ? 35.263  40.311  1.749   0.33  23.798 ? 201 SER D H    1 c 
ATOM   4224 H HA   . SER B 1 33  ? 35.245  38.858  -0.547  0.33  24.717 ? 201 SER D HA   1 c 
ATOM   4225 H HB2  . SER B 1 33  ? 37.512  38.446  -0.109  0.33  25.255 ? 201 SER D HB2  1 c 
ATOM   4226 H HB3  . SER B 1 33  ? 37.185  39.989  0.054   0.33  25.255 ? 201 SER D HB3  1 c 
ATOM   4227 N N    . ASN B 1 34  ? 34.687  37.17   2.035   0.33  24.99  ? 202 ASN D N    1 ? 
ATOM   4228 C CA   . ASN B 1 34  ? 34.463  35.82   2.541   0.33  24.918 ? 202 ASN D CA   1 ? 
ATOM   4229 C C    . ASN B 1 34  ? 32.974  35.467  2.617   0.33  22.454 ? 202 ASN D C    1 ? 
ATOM   4230 O O    . ASN B 1 34  ? 32.605  34.478  3.248   0.33  21.863 ? 202 ASN D O    1 ? 
ATOM   4231 C CB   . ASN B 1 34  ? 35.096  35.603  3.909   0.33  27.906 ? 202 ASN D CB   1 ? 
ATOM   4232 C CG   . ASN B 1 34  ? 35.279  34.137  4.217   0.33  30.94  ? 202 ASN D CG   1 ? 
ATOM   4233 O OD1  . ASN B 1 34  ? 35.844  33.399  3.399   0.33  34.291 ? 202 ASN D OD1  1 ? 
ATOM   4234 N ND2  . ASN B 1 34  ? 34.796  33.693  5.369   0.33  32.163 ? 202 ASN D ND2  1 ? 
ATOM   4235 H H    . ASN B 1 34  ? 34.4    37.887  2.524   0.33  24.796 ? 202 ASN D H    1 c 
ATOM   4236 H HA   . ASN B 1 34  ? 34.892  35.192  1.918   0.33  24.983 ? 202 ASN D HA   1 c 
ATOM   4237 H HB2  . ASN B 1 34  ? 35.967  36.048  3.935   0.33  27.851 ? 202 ASN D HB2  1 c 
ATOM   4238 H HB3  . ASN B 1 34  ? 34.528  36.007  4.595   0.33  27.851 ? 202 ASN D HB3  1 c 
ATOM   4239 H HD21 . ASN B 1 34  ? 34.876  32.836  5.581   0.33  31.782 ? 202 ASN D HD21 1 c 
ATOM   4240 H HD22 . ASN B 1 34  ? 34.393  34.255  5.925   0.33  31.782 ? 202 ASN D HD22 1 c 
ATOM   4241 N N    . VAL B 1 35  ? 32.118  36.247  1.951   0.33  20.237 ? 203 VAL D N    1 ? 
ATOM   4242 C CA   . VAL B 1 35  ? 30.688  35.975  1.956   0.33  18.778 ? 203 VAL D CA   1 ? 
ATOM   4243 C C    . VAL B 1 35  ? 30.44   34.682  1.179   0.33  18.181 ? 203 VAL D C    1 ? 
ATOM   4244 O O    . VAL B 1 35  ? 30.841  34.546  0.034   0.33  17.235 ? 203 VAL D O    1 ? 
ATOM   4245 C CB   . VAL B 1 35  ? 29.874  37.157  1.394   0.33  18.839 ? 203 VAL D CB   1 ? 
ATOM   4246 C CG1  . VAL B 1 35  ? 28.459  36.755  1.004   0.33  18.722 ? 203 VAL D CG1  1 ? 
ATOM   4247 C CG2  . VAL B 1 35  ? 29.806  38.316  2.377   0.33  18.623 ? 203 VAL D CG2  1 ? 
ATOM   4248 H H    . VAL B 1 35  ? 32.432  36.966  1.481   0.33  20.399 ? 203 VAL D H    1 c 
ATOM   4249 H HA   . VAL B 1 35  ? 30.413  35.831  2.882   0.33  18.952 ? 203 VAL D HA   1 c 
ATOM   4250 H HB   . VAL B 1 35  ? 30.337  37.472  0.583   0.33  18.766 ? 203 VAL D HB   1 c 
ATOM   4251 H HG11 . VAL B 1 35  ? 27.993  36.409  1.784   0.33  18.756 ? 203 VAL D HG11 1 c 
ATOM   4252 H HG12 . VAL B 1 35  ? 28.494  36.068  0.318   0.33  18.756 ? 203 VAL D HG12 1 c 
ATOM   4253 H HG13 . VAL B 1 35  ? 27.984  37.53   0.661   0.33  18.756 ? 203 VAL D HG13 1 c 
ATOM   4254 H HG21 . VAL B 1 35  ? 29.285  39.04   1.99    0.33  18.687 ? 203 VAL D HG21 1 c 
ATOM   4255 H HG22 . VAL B 1 35  ? 30.705  38.632  2.569   0.33  18.687 ? 203 VAL D HG22 1 c 
ATOM   4256 H HG23 . VAL B 1 35  ? 29.385  38.019  3.201   0.33  18.687 ? 203 VAL D HG23 1 c 
ATOM   4257 N N    . LYS B 1 36  ? 29.781  33.713  1.826   0.33  18.277 ? 204 LYS D N    1 ? 
ATOM   4258 C CA   . LYS B 1 36  ? 29.591  32.401  1.214   0.33  18.946 ? 204 LYS D CA   1 ? 
ATOM   4259 C C    . LYS B 1 36  ? 28.123  31.972  1.197   0.33  17.139 ? 204 LYS D C    1 ? 
ATOM   4260 O O    . LYS B 1 36  ? 27.803  30.922  0.651   0.33  18.433 ? 204 LYS D O    1 ? 
ATOM   4261 C CB   . LYS B 1 36  ? 30.431  31.344  1.939   0.33  21.433 ? 204 LYS D CB   1 ? 
ATOM   4262 C CG   . LYS B 1 36  ? 31.944  31.469  1.771   0.33  23.769 ? 204 LYS D CG   1 ? 
ATOM   4263 C CD   . LYS B 1 36  ? 32.462  31.34   0.348   0.33  25.74  ? 204 LYS D CD   1 ? 
ATOM   4264 C CE   . LYS B 1 36  ? 33.961  31.457  0.292   0.33  27.215 ? 204 LYS D CE   1 ? 
ATOM   4265 N NZ   . LYS B 1 36  ? 34.446  31.54   -1.084  0.33  28.401 ? 204 LYS D NZ   1 ? 
ATOM   4266 H H    . LYS B 1 36  ? 29.444  33.869  2.661   0.33  18.402 ? 204 LYS D H    1 c 
ATOM   4267 H HA   . LYS B 1 36  ? 29.907  32.454  0.277   0.33  18.894 ? 204 LYS D HA   1 c 
ATOM   4268 H HB2  . LYS B 1 36  ? 30.223  31.387  2.897   0.33  21.339 ? 204 LYS D HB2  1 c 
ATOM   4269 H HB3  . LYS B 1 36  ? 30.159  30.458  1.617   0.33  21.339 ? 204 LYS D HB3  1 c 
ATOM   4270 H HG2  . LYS B 1 36  ? 32.221  32.342  2.127   0.33  23.641 ? 204 LYS D HG2  1 c 
ATOM   4271 H HG3  . LYS B 1 36  ? 32.372  30.779  2.324   0.33  23.641 ? 204 LYS D HG3  1 c 
ATOM   4272 H HD2  . LYS B 1 36  ? 32.192  30.469  -0.016  0.33  25.605 ? 204 LYS D HD2  1 c 
ATOM   4273 H HD3  . LYS B 1 36  ? 32.062  32.044  -0.207  0.33  25.605 ? 204 LYS D HD3  1 c 
ATOM   4274 H HE2  . LYS B 1 36  ? 34.243  32.254  0.776   0.33  27.146 ? 204 LYS D HE2  1 c 
ATOM   4275 H HE3  . LYS B 1 36  ? 34.363  30.682  0.724   0.33  27.146 ? 204 LYS D HE3  1 c 
ATOM   4276 H HZ1  . LYS B 1 36  ? 34.146  32.303  -1.469  0.33  28.031 ? 204 LYS D HZ1  1 c 
ATOM   4277 H HZ2  . LYS B 1 36  ? 34.145  30.829  -1.559  0.33  28.031 ? 204 LYS D HZ2  1 c 
ATOM   4278 H HZ3  . LYS B 1 36  ? 35.352  31.54   -1.09   0.33  28.031 ? 204 LYS D HZ3  1 c 
ATOM   4279 N N    . SER B 1 37  ? 27.236  32.797  1.759   0.33  16.525 ? 205 SER D N    1 ? 
ATOM   4280 C CA   . SER B 1 37  ? 25.809  32.512  1.793   0.33  14.637 ? 205 SER D CA   1 ? 
ATOM   4281 C C    . SER B 1 37  ? 25.069  33.832  1.96    0.33  14.117 ? 205 SER D C    1 ? 
ATOM   4282 O O    . SER B 1 37  ? 25.629  34.772  2.533   0.33  14.924 ? 205 SER D O    1 ? 
ATOM   4283 C CB   . SER B 1 37  ? 25.508  31.564  2.923   0.33  14.737 ? 205 SER D CB   1 ? 
ATOM   4284 O OG   . SER B 1 37  ? 25.8    32.182  4.166   0.33  13.87  ? 205 SER D OG   1 ? 
ATOM   4285 H H    . SER B 1 37  ? 27.535  33.572  2.14    0.33  16.219 ? 205 SER D H    1 c 
ATOM   4286 H HA   . SER B 1 37  ? 25.542  32.096  0.934   0.33  14.905 ? 205 SER D HA   1 c 
ATOM   4287 H HB2  . SER B 1 37  ? 24.566  31.312  2.895   0.33  14.504 ? 205 SER D HB2  1 c 
ATOM   4288 H HB3  . SER B 1 37  ? 26.048  30.757  2.823   0.33  14.504 ? 205 SER D HB3  1 c 
ATOM   4289 N N    . PHE B 1 38  ? 23.821  33.896  1.492   0.33  12.175 ? 206 PHE D N    1 ? 
ATOM   4290 C CA   . PHE B 1 38  ? 23.007  35.082  1.68    0.33  11.844 ? 206 PHE D CA   1 ? 
ATOM   4291 C C    . PHE B 1 38  ? 21.53   34.695  1.688   0.33  11.405 ? 206 PHE D C    1 ? 
ATOM   4292 O O    . PHE B 1 38  ? 21.118  33.69   1.107   0.33  11.989 ? 206 PHE D O    1 ? 
ATOM   4293 C CB   . PHE B 1 38  ? 23.316  36.146  0.613   0.33  11.293 ? 206 PHE D CB   1 ? 
ATOM   4294 C CG   . PHE B 1 38  ? 22.692  35.873  -0.752  0.33  10.827 ? 206 PHE D CG   1 ? 
ATOM   4295 C CD1  . PHE B 1 38  ? 23.277  34.966  -1.628  0.33  10.667 ? 206 PHE D CD1  1 ? 
ATOM   4296 C CD2  . PHE B 1 38  ? 21.527  36.524  -1.155  0.33  10.7   ? 206 PHE D CD2  1 ? 
ATOM   4297 C CE1  . PHE B 1 38  ? 22.711  34.705  -2.869  0.33  10.813 ? 206 PHE D CE1  1 ? 
ATOM   4298 C CE2  . PHE B 1 38  ? 20.964  36.258  -2.396  0.33  10.915 ? 206 PHE D CE2  1 ? 
ATOM   4299 C CZ   . PHE B 1 38  ? 21.563  35.358  -3.259  0.33  10.62  ? 206 PHE D CZ   1 ? 
ATOM   4300 H H    . PHE B 1 38  ? 23.468  33.182  1.044   0.33  12.535 ? 206 PHE D H    1 c 
ATOM   4301 H HA   . PHE B 1 38  ? 23.229  35.466  2.57    0.33  11.724 ? 206 PHE D HA   1 c 
ATOM   4302 H HB2  . PHE B 1 38  ? 22.996  37.016  0.94    0.33  11.306 ? 206 PHE D HB2  1 c 
ATOM   4303 H HB3  . PHE B 1 38  ? 24.292  36.207  0.509   0.33  11.306 ? 206 PHE D HB3  1 c 
ATOM   4304 H HD1  . PHE B 1 38  ? 24.066  34.516  -1.371  0.33  10.741 ? 206 PHE D HD1  1 c 
ATOM   4305 H HD2  . PHE B 1 38  ? 21.113  37.142  -0.574  0.33  10.781 ? 206 PHE D HD2  1 c 
ATOM   4306 H HE1  . PHE B 1 38  ? 23.123  34.088  -3.452  0.33  10.736 ? 206 PHE D HE1  1 c 
ATOM   4307 H HE2  . PHE B 1 38  ? 20.177  36.708  -2.659  0.33  10.796 ? 206 PHE D HE2  1 c 
ATOM   4308 H HZ   . PHE B 1 38  ? 21.179  35.181  -4.103  0.33  10.734 ? 206 PHE D HZ   1 c 
ATOM   4309 N N    . THR B 1 39  ? 20.742  35.51   2.386   0.33  11.358 ? 207 THR D N    1 ? 
ATOM   4310 C CA   . THR B 1 39  ? 19.293  35.453  2.263   0.33  10.946 ? 207 THR D CA   1 ? 
ATOM   4311 C C    . THR B 1 39  ? 18.798  36.809  1.749   0.33  11.261 ? 207 THR D C    1 ? 
ATOM   4312 O O    . THR B 1 39  ? 19.552  37.778  1.64    0.33  10.518 ? 207 THR D O    1 ? 
ATOM   4313 C CB   . THR B 1 39  ? 18.65   35.007  3.58    0.33  10.581 ? 207 THR D CB   1 ? 
ATOM   4314 O OG1  . THR B 1 39  ? 17.252  34.908  3.314   0.33  10.506 ? 207 THR D OG1  1 ? 
ATOM   4315 C CG2  . THR B 1 39  ? 18.874  35.997  4.713   0.33  10.396 ? 207 THR D CG2  1 ? 
ATOM   4316 H H    . THR B 1 39  ? 21.115  36.119  2.957   0.33  11.275 ? 207 THR D H    1 c 
ATOM   4317 H HA   . THR B 1 39  ? 19.081  34.777  1.583   0.33  11.013 ? 207 THR D HA   1 c 
ATOM   4318 H HB   . THR B 1 39  ? 18.999  34.122  3.841   0.33  10.597 ? 207 THR D HB   1 c 
ATOM   4319 H HG21 . THR B 1 39  ? 18.439  35.672  5.519   0.33  10.45  ? 207 THR D HG21 1 c 
ATOM   4320 H HG22 . THR B 1 39  ? 18.499  36.86   4.469   0.33  10.45  ? 207 THR D HG22 1 c 
ATOM   4321 H HG23 . THR B 1 39  ? 19.827  36.093  4.876   0.33  10.45  ? 207 THR D HG23 1 c 
ATOM   4322 N N    . TYR B 1 40  ? 17.521  36.837  1.364   0.33  10.791 ? 208 TYR D N    1 ? 
ATOM   4323 C CA   . TYR B 1 40  ? 16.989  37.863  0.487   0.33  11.52  ? 208 TYR D CA   1 ? 
ATOM   4324 C C    . TYR B 1 40  ? 15.487  37.9    0.715   0.33  11.107 ? 208 TYR D C    1 ? 
ATOM   4325 O O    . TYR B 1 40  ? 14.774  36.994  0.277   0.33  10.281 ? 208 TYR D O    1 ? 
ATOM   4326 C CB   . TYR B 1 40  ? 17.397  37.465  -0.939  0.33  11.322 ? 208 TYR D CB   1 ? 
ATOM   4327 C CG   . TYR B 1 40  ? 17.055  38.394  -2.102  0.33  12.205 ? 208 TYR D CG   1 ? 
ATOM   4328 C CD1  . TYR B 1 40  ? 16.577  39.693  -1.926  0.33  12.33  ? 208 TYR D CD1  1 ? 
ATOM   4329 C CD2  . TYR B 1 40  ? 17.273  37.961  -3.401  0.33  13.217 ? 208 TYR D CD2  1 ? 
ATOM   4330 C CE1  . TYR B 1 40  ? 16.296  40.513  -3.01   0.33  12.402 ? 208 TYR D CE1  1 ? 
ATOM   4331 C CE2  . TYR B 1 40  ? 16.989  38.765  -4.493  0.33  12.786 ? 208 TYR D CE2  1 ? 
ATOM   4332 C CZ   . TYR B 1 40  ? 16.504  40.039  -4.3    0.33  12.488 ? 208 TYR D CZ   1 ? 
ATOM   4333 O OH   . TYR B 1 40  ? 16.244  40.765  -5.428  0.33  12.64  ? 208 TYR D OH   1 ? 
ATOM   4334 H H    . TYR B 1 40  ? 16.957  36.184  1.664   0.33  11.063 ? 208 TYR D H    1 c 
ATOM   4335 H HA   . TYR B 1 40  ? 17.389  38.742  0.72    0.33  11.264 ? 208 TYR D HA   1 c 
ATOM   4336 H HB2  . TYR B 1 40  ? 18.37   37.326  -0.94   0.33  11.564 ? 208 TYR D HB2  1 c 
ATOM   4337 H HB3  . TYR B 1 40  ? 16.997  36.587  -1.127  0.33  11.564 ? 208 TYR D HB3  1 c 
ATOM   4338 H HD1  . TYR B 1 40  ? 16.431  40.018  -1.052  0.33  12.321 ? 208 TYR D HD1  1 c 
ATOM   4339 H HD2  . TYR B 1 40  ? 17.6    37.088  -3.547  0.33  12.856 ? 208 TYR D HD2  1 c 
ATOM   4340 H HE1  . TYR B 1 40  ? 15.958  41.382  -2.873  0.33  12.409 ? 208 TYR D HE1  1 c 
ATOM   4341 H HE2  . TYR B 1 40  ? 17.13   38.442  -5.367  0.33  12.802 ? 208 TYR D HE2  1 c 
ATOM   4342 N N    . GLN B 1 41  ? 15.028  38.919  1.447   0.33  10.769 ? 209 GLN D N    1 ? 
ATOM   4343 C CA   . GLN B 1 41  ? 13.626  39.011  1.814   0.33  12.083 ? 209 GLN D CA   1 ? 
ATOM   4344 C C    . GLN B 1 41  ? 13.226  40.479  1.783   0.33  12.222 ? 209 GLN D C    1 ? 
ATOM   4345 O O    . GLN B 1 41  ? 13.866  41.307  2.426   0.33  11.569 ? 209 GLN D O    1 ? 
ATOM   4346 C CB   . GLN B 1 41  ? 13.296  38.462  3.204   0.33  12.154 ? 209 GLN D CB   1 ? 
ATOM   4347 C CG   . GLN B 1 41  ? 11.816  38.558  3.57    0.33  11.988 ? 209 GLN D CG   1 ? 
ATOM   4348 C CD   . GLN B 1 41  ? 11.449  37.918  4.891   0.33  12.478 ? 209 GLN D CD   1 ? 
ATOM   4349 O OE1  . GLN B 1 41  ? 10.309  38.029  5.369   0.33  13.917 ? 209 GLN D OE1  1 ? 
ATOM   4350 N NE2  . GLN B 1 41  ? 12.431  37.287  5.519   0.33  12.148 ? 209 GLN D NE2  1 ? 
ATOM   4351 H H    . GLN B 1 41  ? 15.603  39.573  1.725   0.33  11.134 ? 209 GLN D H    1 c 
ATOM   4352 H HA   . GLN B 1 41  ? 13.093  38.521  1.137   0.33  11.851 ? 209 GLN D HA   1 c 
ATOM   4353 H HB2  . GLN B 1 41  ? 13.574  37.523  3.244   0.33  12.1   ? 209 GLN D HB2  1 c 
ATOM   4354 H HB3  . GLN B 1 41  ? 13.821  38.956  3.869   0.33  12.1   ? 209 GLN D HB3  1 c 
ATOM   4355 H HG2  . GLN B 1 41  ? 11.557  39.503  3.602   0.33  12.137 ? 209 GLN D HG2  1 c 
ATOM   4356 H HG3  . GLN B 1 41  ? 11.286  38.132  2.863   0.33  12.137 ? 209 GLN D HG3  1 c 
ATOM   4357 H HE21 . GLN B 1 41  ? 12.279  36.901  6.303   0.33  12.248 ? 209 GLN D HE21 1 c 
ATOM   4358 H HE22 . GLN B 1 41  ? 13.239  37.253  5.154   0.33  12.248 ? 209 GLN D HE22 1 c 
ATOM   4359 N N    . LEU B 1 42  ? 12.159  40.767  1.029   0.33  12.43  ? 210 LEU D N    1 ? 
ATOM   4360 C CA   . LEU B 1 42  ? 11.764  42.124  0.725   0.33  13.237 ? 210 LEU D CA   1 ? 
ATOM   4361 C C    . LEU B 1 42  ? 10.414  42.456  1.357   0.33  14.373 ? 210 LEU D C    1 ? 
ATOM   4362 O O    . LEU B 1 42  ? 10.048  43.617  1.363   0.33  15.643 ? 210 LEU D O    1 ? 
ATOM   4363 C CB   . LEU B 1 42  ? 11.739  42.392  -0.782  0.33  13.202 ? 210 LEU D CB   1 ? 
ATOM   4364 C CG   . LEU B 1 42  ? 13.038  42.105  -1.538  0.33  13.398 ? 210 LEU D CG   1 ? 
ATOM   4365 C CD1  . LEU B 1 42  ? 12.778  42.461  -2.979  0.33  13.607 ? 210 LEU D CD1  1 ? 
ATOM   4366 C CD2  . LEU B 1 42  ? 14.239  42.854  -0.947  0.33  13.935 ? 210 LEU D CD2  1 ? 
ATOM   4367 H H    . LEU B 1 42  ? 11.658  40.08   0.692   0.33  12.558 ? 210 LEU D H    1 c 
ATOM   4368 H HA   . LEU B 1 42  ? 12.437  42.724  1.135   0.33  13.27  ? 210 LEU D HA   1 c 
ATOM   4369 H HB2  . LEU B 1 42  ? 11.022  41.846  -1.179  0.33  13.254 ? 210 LEU D HB2  1 c 
ATOM   4370 H HB3  . LEU B 1 42  ? 11.502  43.338  -0.921  0.33  13.254 ? 210 LEU D HB3  1 c 
ATOM   4371 H HG   . LEU B 1 42  ? 13.221  41.131  -1.486  0.33  13.498 ? 210 LEU D HG   1 c 
ATOM   4372 H HD11 . LEU B 1 42  ? 12.04   41.927  -3.317  0.33  13.544 ? 210 LEU D HD11 1 c 
ATOM   4373 H HD12 . LEU B 1 42  ? 13.574  42.284  -3.507  0.33  13.544 ? 210 LEU D HD12 1 c 
ATOM   4374 H HD13 . LEU B 1 42  ? 12.55   43.404  -3.044  0.33  13.544 ? 210 LEU D HD13 1 c 
ATOM   4375 H HD21 . LEU B 1 42  ? 14.368  42.582  -0.022  0.33  13.775 ? 210 LEU D HD21 1 c 
ATOM   4376 H HD22 . LEU B 1 42  ? 14.074  43.811  -0.981  0.33  13.775 ? 210 LEU D HD22 1 c 
ATOM   4377 H HD23 . LEU B 1 42  ? 15.037  42.645  -1.46   0.33  13.775 ? 210 LEU D HD23 1 c 
ATOM   4378 N N    . THR B 1 43  ? 9.674   41.476  1.886   0.33  14.786 ? 211 THR D N    1 ? 
ATOM   4379 C CA   . THR B 1 43  ? 8.354   41.767  2.432   0.33  15.966 ? 211 THR D CA   1 ? 
ATOM   4380 C C    . THR B 1 43  ? 7.973   40.7    3.454   0.33  16.739 ? 211 THR D C    1 ? 
ATOM   4381 O O    . THR B 1 43  ? 8.687   39.723  3.611   0.33  16.037 ? 211 THR D O    1 ? 
ATOM   4382 C CB   . THR B 1 43  ? 7.352   41.849  1.28    0.33  17.563 ? 211 THR D CB   1 ? 
ATOM   4383 O OG1  . THR B 1 43  ? 6.182   42.506  1.767   0.33  19.143 ? 211 THR D OG1  1 ? 
ATOM   4384 C CG2  . THR B 1 43  ? 7.029   40.491  0.68    0.33  17.179 ? 211 THR D CG2  1 ? 
ATOM   4385 H H    . THR B 1 43  ? 9.991   40.619  1.908   0.33  14.941 ? 211 THR D H    1 c 
ATOM   4386 H HA   . THR B 1 43  ? 8.389   42.64   2.882   0.33  16.145 ? 211 THR D HA   1 c 
ATOM   4387 H HB   . THR B 1 43  ? 7.748   42.403  0.566   0.33  17.479 ? 211 THR D HB   1 c 
ATOM   4388 H HG21 . THR B 1 43  ? 6.397   40.6    -0.05   0.33  17.291 ? 211 THR D HG21 1 c 
ATOM   4389 H HG22 . THR B 1 43  ? 6.639   39.919  1.362   0.33  17.291 ? 211 THR D HG22 1 c 
ATOM   4390 H HG23 . THR B 1 43  ? 7.845   40.082  0.343   0.33  17.291 ? 211 THR D HG23 1 c 
ATOM   4391 N N    . ASN B 1 44  ? 6.841   40.902  4.147   0.33  17.526 ? 212 ASN D N    1 ? 
ATOM   4392 C CA   . ASN B 1 44  ? 6.321   39.935  5.112   0.33  18.991 ? 212 ASN D CA   1 ? 
ATOM   4393 C C    . ASN B 1 44  ? 7.307   39.711  6.256   0.33  18.792 ? 212 ASN D C    1 ? 
ATOM   4394 O O    . ASN B 1 44  ? 7.555   38.576  6.669   0.33  21.239 ? 212 ASN D O    1 ? 
ATOM   4395 C CB   . ASN B 1 44  ? 5.964   38.63   4.411   0.33  20.155 ? 212 ASN D CB   1 ? 
ATOM   4396 C CG   . ASN B 1 44  ? 5.146   37.697  5.272   0.33  22.673 ? 212 ASN D CG   1 ? 
ATOM   4397 O OD1  . ASN B 1 44  ? 4.297   38.15   6.047   0.33  23.614 ? 212 ASN D OD1  1 ? 
ATOM   4398 N ND2  . ASN B 1 44  ? 5.376   36.399  5.144   0.33  22.856 ? 212 ASN D ND2  1 ? 
ATOM   4399 H H    . ASN B 1 44  ? 6.375   41.676  4.011   0.33  17.651 ? 212 ASN D H    1 c 
ATOM   4400 H HA   . ASN B 1 44  ? 5.49    40.302  5.49    0.33  18.868 ? 212 ASN D HA   1 c 
ATOM   4401 H HB2  . ASN B 1 44  ? 5.46    38.833  3.598   0.33  20.431 ? 212 ASN D HB2  1 c 
ATOM   4402 H HB3  . ASN B 1 44  ? 6.788   38.175  4.146   0.33  20.431 ? 212 ASN D HB3  1 c 
ATOM   4403 H HD21 . ASN B 1 44  ? 4.914   35.818  5.629   0.33  22.8   ? 212 ASN D HD21 1 c 
ATOM   4404 H HD22 . ASN B 1 44  ? 5.992   36.114  4.573   0.33  22.8   ? 212 ASN D HD22 1 c 
ATOM   4405 N N    . TYR B 1 45  ? 7.921   40.792  6.746   0.33  18.913 ? 213 TYR D N    1 ? 
ATOM   4406 C CA   . TYR B 1 45  ? 8.818   40.69   7.89    0.33  19.304 ? 213 TYR D CA   1 ? 
ATOM   4407 C C    . TYR B 1 45  ? 7.983   40.361  9.12    0.33  21.525 ? 213 TYR D C    1 ? 
ATOM   4408 O O    . TYR B 1 45  ? 7.032   41.078  9.41    0.33  25.924 ? 213 TYR D O    1 ? 
ATOM   4409 C CB   . TYR B 1 45  ? 9.614   41.985  8.084   0.33  17.582 ? 213 TYR D CB   1 ? 
ATOM   4410 C CG   . TYR B 1 45  ? 10.461  42.35   6.876   0.33  16.251 ? 213 TYR D CG   1 ? 
ATOM   4411 C CD1  . TYR B 1 45  ? 11.641  41.672  6.594   0.33  15.595 ? 213 TYR D CD1  1 ? 
ATOM   4412 C CD2  . TYR B 1 45  ? 10.084  43.372  6.018   0.33  15.401 ? 213 TYR D CD2  1 ? 
ATOM   4413 C CE1  . TYR B 1 45  ? 12.42   42.008  5.495   0.33  15.451 ? 213 TYR D CE1  1 ? 
ATOM   4414 C CE2  . TYR B 1 45  ? 10.86   43.732  4.934   0.33  14.676 ? 213 TYR D CE2  1 ? 
ATOM   4415 C CZ   . TYR B 1 45  ? 12.019  43.033  4.655   0.33  14.91  ? 213 TYR D CZ   1 ? 
ATOM   4416 O OH   . TYR B 1 45  ? 12.77   43.379  3.563   0.33  13.952 ? 213 TYR D OH   1 ? 
ATOM   4417 H H    . TYR B 1 45  ? 7.779   41.609  6.362   0.33  18.971 ? 213 TYR D H    1 c 
ATOM   4418 H HA   . TYR B 1 45  ? 9.455   39.944  7.727   0.33  19.285 ? 213 TYR D HA   1 c 
ATOM   4419 H HB2  . TYR B 1 45  ? 8.984   42.717  8.267   0.33  17.639 ? 213 TYR D HB2  1 c 
ATOM   4420 H HB3  . TYR B 1 45  ? 10.199  41.88   8.867   0.33  17.639 ? 213 TYR D HB3  1 c 
ATOM   4421 H HD1  . TYR B 1 45  ? 11.918  40.968  7.159   0.33  15.704 ? 213 TYR D HD1  1 c 
ATOM   4422 H HD2  . TYR B 1 45  ? 9.292   43.855  6.197   0.33  15.423 ? 213 TYR D HD2  1 c 
ATOM   4423 H HE1  . TYR B 1 45  ? 13.214  41.534  5.315   0.33  15.354 ? 213 TYR D HE1  1 c 
ATOM   4424 H HE2  . TYR B 1 45  ? 10.578  44.424  4.36    0.33  14.911 ? 213 TYR D HE2  1 c 
ATOM   4425 N N    . PRO B 1 46  ? 8.276   39.276  9.874   0.33  21.965 ? 214 PRO D N    1 ? 
ATOM   4426 C CA   . PRO B 1 46  ? 7.44    38.892  11.016  0.33  22.683 ? 214 PRO D CA   1 ? 
ATOM   4427 C C    . PRO B 1 46  ? 7.456   39.986  12.076  0.33  23.189 ? 214 PRO D C    1 ? 
ATOM   4428 O O    . PRO B 1 46  ? 8.532   40.405  12.503  0.33  22.183 ? 214 PRO D O    1 ? 
ATOM   4429 C CB   . PRO B 1 46  ? 8.059   37.582  11.502  0.33  21.521 ? 214 PRO D CB   1 ? 
ATOM   4430 C CG   . PRO B 1 46  ? 8.831   37.086  10.303  0.33  21.697 ? 214 PRO D CG   1 ? 
ATOM   4431 C CD   . PRO B 1 46  ? 9.404   38.353  9.691   0.33  20.814 ? 214 PRO D CD   1 ? 
ATOM   4432 H HA   . PRO B 1 46  ? 6.513   38.731  10.706  0.33  22.419 ? 214 PRO D HA   1 c 
ATOM   4433 H HB2  . PRO B 1 46  ? 8.66    37.739  12.269  0.33  21.815 ? 214 PRO D HB2  1 c 
ATOM   4434 H HB3  . PRO B 1 46  ? 7.361   36.937  11.765  0.33  21.815 ? 214 PRO D HB3  1 c 
ATOM   4435 H HG2  . PRO B 1 46  ? 9.546   36.473  10.574  0.33  21.455 ? 214 PRO D HG2  1 c 
ATOM   4436 H HG3  . PRO B 1 46  ? 8.24    36.628  9.67    0.33  21.455 ? 214 PRO D HG3  1 c 
ATOM   4437 H HD2  . PRO B 1 46  ? 10.202  38.658  10.177  0.33  21.271 ? 214 PRO D HD2  1 c 
ATOM   4438 H HD3  . PRO B 1 46  ? 9.618   38.228  8.74    0.33  21.271 ? 214 PRO D HD3  1 c 
ATOM   4439 N N    . GLN B 1 47  ? 6.25    40.472  12.414  0.33  26.341 ? 215 GLN D N    1 ? 
ATOM   4440 C CA   . GLN B 1 47  ? 6.032   41.536  13.384  0.33  29.262 ? 215 GLN D CA   1 ? 
ATOM   4441 C C    . GLN B 1 47  ? 6.786   42.787  12.941  0.33  27.26  ? 215 GLN D C    1 ? 
ATOM   4442 O O    . GLN B 1 47  ? 7.076   43.67   13.748  0.33  27.519 ? 215 GLN D O    1 ? 
ATOM   4443 C CB   . GLN B 1 47  ? 6.424   41.133  14.805  0.33  32.386 ? 215 GLN D CB   1 ? 
ATOM   4444 C CG   . GLN B 1 47  ? 5.602   39.988  15.386  0.33  33.504 ? 215 GLN D CG   1 ? 
ATOM   4445 C CD   . GLN B 1 47  ? 5.986   38.652  14.793  0.33  36.363 ? 215 GLN D CD   1 ? 
ATOM   4446 O OE1  . GLN B 1 47  ? 7.132   38.208  14.912  0.33  40.155 ? 215 GLN D OE1  1 ? 
ATOM   4447 N NE2  . GLN B 1 47  ? 5.043   38.007  14.125  0.33  38.893 ? 215 GLN D NE2  1 ? 
ATOM   4448 H H    . GLN B 1 47  ? 5.516   40.111  12.006  0.33  26.171 ? 215 GLN D H    1 c 
ATOM   4449 H HA   . GLN B 1 47  ? 5.064   41.748  13.388  0.33  28.832 ? 215 GLN D HA   1 c 
ATOM   4450 H HB2  . GLN B 1 47  ? 7.369   40.875  14.806  0.33  31.891 ? 215 GLN D HB2  1 c 
ATOM   4451 H HB3  . GLN B 1 47  ? 6.33    41.916  15.387  0.33  31.891 ? 215 GLN D HB3  1 c 
ATOM   4452 H HG2  . GLN B 1 47  ? 5.731   39.955  16.358  0.33  33.88  ? 215 GLN D HG2  1 c 
ATOM   4453 H HG3  . GLN B 1 47  ? 4.65    40.151  15.215  0.33  33.88  ? 215 GLN D HG3  1 c 
ATOM   4454 H HE21 . GLN B 1 47  ? 5.223   37.224  13.75   0.33  38.096 ? 215 GLN D HE21 1 c 
ATOM   4455 H HE22 . GLN B 1 47  ? 4.232   38.359  14.055  0.33  38.096 ? 215 GLN D HE22 1 c 
ATOM   4456 N N    . GLY B 1 48  ? 7.063   42.856  11.637  0.33  25.887 ? 216 GLY D N    1 ? 
ATOM   4457 C CA   . GLY B 1 48  ? 7.732   43.994  11.035  0.33  24.244 ? 216 GLY D CA   1 ? 
ATOM   4458 C C    . GLY B 1 48  ? 9.221   44.035  11.377  0.33  22.418 ? 216 GLY D C    1 ? 
ATOM   4459 O O    . GLY B 1 48  ? 9.869   45.051  11.143  0.33  20.979 ? 216 GLY D O    1 ? 
ATOM   4460 H H    . GLY B 1 48  ? 6.821   42.158  11.098  0.33  25.821 ? 216 GLY D H    1 c 
ATOM   4461 H HA2  . GLY B 1 48  ? 7.622   43.951  10.057  0.33  24.202 ? 216 GLY D HA2  1 c 
ATOM   4462 H HA3  . GLY B 1 48  ? 7.301   44.823  11.351  0.33  24.202 ? 216 GLY D HA3  1 c 
ATOM   4463 N N    . LYS B 1 49  ? 9.781   42.904  11.835  0.33  20.154 ? 217 LYS D N    1 ? 
ATOM   4464 C CA   . LYS B 1 49  ? 11.133  42.886  12.367  0.33  20.248 ? 217 LYS D CA   1 ? 
ATOM   4465 C C    . LYS B 1 49  ? 12.037  41.957  11.556  0.33  18.968 ? 217 LYS D C    1 ? 
ATOM   4466 O O    . LYS B 1 49  ? 11.574  41.136  10.764  0.33  17.326 ? 217 LYS D O    1 ? 
ATOM   4467 C CB   . LYS B 1 49  ? 11.084  42.494  13.846  0.33  21.912 ? 217 LYS D CB   1 ? 
ATOM   4468 H H    . LYS B 1 49  ? 9.304   42.125  11.813  0.33  20.694 ? 217 LYS D H    1 c 
ATOM   4469 H HA   . LYS B 1 49  ? 11.498  43.805  12.304  0.33  20.28  ? 217 LYS D HA   1 c 
ATOM   4470 N N    . LEU B 1 50  ? 13.343  42.117  11.792  0.33  17.816 ? 218 LEU D N    1 ? 
ATOM   4471 C CA   . LEU B 1 50  ? 14.386  41.372  11.099  0.33  17.506 ? 218 LEU D CA   1 ? 
ATOM   4472 C C    . LEU B 1 50  ? 14.924  40.216  11.954  0.33  17.674 ? 218 LEU D C    1 ? 
ATOM   4473 O O    . LEU B 1 50  ? 15.968  39.639  11.638  0.33  16.568 ? 218 LEU D O    1 ? 
ATOM   4474 C CB   . LEU B 1 50  ? 15.482  42.374  10.742  0.33  17.891 ? 218 LEU D CB   1 ? 
ATOM   4475 C CG   . LEU B 1 50  ? 15.088  43.489  9.765   0.33  18.88  ? 218 LEU D CG   1 ? 
ATOM   4476 C CD1  . LEU B 1 50  ? 16.212  44.508  9.679   0.33  18.67  ? 218 LEU D CD1  1 ? 
ATOM   4477 C CD2  . LEU B 1 50  ? 14.752  42.915  8.394   0.33  19.046 ? 218 LEU D CD2  1 ? 
ATOM   4478 H H    . LEU B 1 50  ? 13.597  42.727  12.423  0.33  18.012 ? 218 LEU D H    1 c 
ATOM   4479 H HA   . LEU B 1 50  ? 14.001  40.998  10.266  0.33  17.666 ? 218 LEU D HA   1 c 
ATOM   4480 H HB2  . LEU B 1 50  ? 15.799  42.791  11.576  0.33  18.021 ? 218 LEU D HB2  1 c 
ATOM   4481 H HB3  . LEU B 1 50  ? 16.238  41.876  10.355  0.33  18.021 ? 218 LEU D HB3  1 c 
ATOM   4482 H HG   . LEU B 1 50  ? 14.281  43.944  10.119  0.33  18.686 ? 218 LEU D HG   1 c 
ATOM   4483 H HD11 . LEU B 1 50  ? 16.385  44.877  10.562  0.33  18.732 ? 218 LEU D HD11 1 c 
ATOM   4484 H HD12 . LEU B 1 50  ? 15.956  45.225  9.075   0.33  18.732 ? 218 LEU D HD12 1 c 
ATOM   4485 H HD13 . LEU B 1 50  ? 17.017  44.078  9.346   0.33  18.732 ? 218 LEU D HD13 1 c 
ATOM   4486 H HD21 . LEU B 1 50  ? 14.008  42.294  8.474   0.33  18.997 ? 218 LEU D HD21 1 c 
ATOM   4487 H HD22 . LEU B 1 50  ? 15.527  42.446  8.039   0.33  18.997 ? 218 LEU D HD22 1 c 
ATOM   4488 H HD23 . LEU B 1 50  ? 14.507  43.636  7.79    0.33  18.997 ? 218 LEU D HD23 1 c 
ATOM   4489 N N    . ASP B 1 51  ? 14.199  39.846  13.025  0.33  18.235 ? 219 ASP D N    1 ? 
ATOM   4490 C CA   . ASP B 1 51  ? 14.708  38.922  14.035  0.33  18.672 ? 219 ASP D CA   1 ? 
ATOM   4491 C C    . ASP B 1 51  ? 14.99   37.546  13.441  0.33  17.126 ? 219 ASP D C    1 ? 
ATOM   4492 O O    . ASP B 1 51  ? 15.982  36.925  13.795  0.33  19.814 ? 219 ASP D O    1 ? 
ATOM   4493 C CB   . ASP B 1 51  ? 13.805  38.862  15.258  0.33  19.325 ? 219 ASP D CB   1 ? 
ATOM   4494 C CG   . ASP B 1 51  ? 13.646  40.177  16.015  0.33  20.858 ? 219 ASP D CG   1 ? 
ATOM   4495 O OD1  . ASP B 1 51  ? 14.356  41.131  15.667  0.33  21.106 ? 219 ASP D OD1  1 ? 
ATOM   4496 O OD2  . ASP B 1 51  ? 12.777  40.259  16.916  0.33  21.643 ? 219 ASP D OD2  1 ? 
ATOM   4497 H H    . ASP B 1 51  ? 13.355  40.184  13.126  0.33  18.196 ? 219 ASP D H    1 c 
ATOM   4498 H HA   . ASP B 1 51  ? 15.563  39.284  14.359  0.33  18.413 ? 219 ASP D HA   1 c 
ATOM   4499 H HB2  . ASP B 1 51  ? 12.915  38.563  14.977  0.33  19.512 ? 219 ASP D HB2  1 c 
ATOM   4500 H HB3  . ASP B 1 51  ? 14.163  38.194  15.88   0.33  19.512 ? 219 ASP D HB3  1 c 
ATOM   4501 N N    . ALA B 1 52  ? 14.136  37.058  12.546  0.33  16.68  ? 220 ALA D N    1 ? 
ATOM   4502 C CA   . ALA B 1 52  ? 14.348  35.749  11.943  0.33  15.49  ? 220 ALA D CA   1 ? 
ATOM   4503 C C    . ALA B 1 52  ? 15.587  35.785  11.049  0.33  15.143 ? 220 ALA D C    1 ? 
ATOM   4504 O O    . ALA B 1 52  ? 16.379  34.848  11.043  0.33  14.411 ? 220 ALA D O    1 ? 
ATOM   4505 C CB   . ALA B 1 52  ? 13.109  35.3    11.203  0.33  14.594 ? 220 ALA D CB   1 ? 
ATOM   4506 H H    . ALA B 1 52  ? 13.403  37.548  12.303  0.33  16.509 ? 220 ALA D H    1 c 
ATOM   4507 H HA   . ALA B 1 52  ? 14.526  35.103  12.681  0.33  15.479 ? 220 ALA D HA   1 c 
ATOM   4508 H HB1  . ALA B 1 52  ? 12.36   35.246  11.821  0.33  14.854 ? 220 ALA D HB1  1 c 
ATOM   4509 H HB2  . ALA B 1 52  ? 12.899  35.938  10.5    0.33  14.854 ? 220 ALA D HB2  1 c 
ATOM   4510 H HB3  . ALA B 1 52  ? 13.263  34.426  10.808  0.33  14.854 ? 220 ALA D HB3  1 c 
ATOM   4511 N N    . ILE B 1 53  ? 15.796  36.903  10.343  0.33  16.543 ? 221 ILE D N    1 ? 
ATOM   4512 C CA   . ILE B 1 53  ? 16.986  37.047  9.52    0.33  16.472 ? 221 ILE D CA   1 ? 
ATOM   4513 C C    . ILE B 1 53  ? 18.22   37.099  10.428  0.33  15.331 ? 221 ILE D C    1 ? 
ATOM   4514 O O    . ILE B 1 53  ? 19.217  36.434  10.183  0.33  14.59  ? 221 ILE D O    1 ? 
ATOM   4515 C CB   . ILE B 1 53  ? 16.85   38.276  8.598   0.33  16.926 ? 221 ILE D CB   1 ? 
ATOM   4516 C CG1  . ILE B 1 53  ? 15.695  38.105  7.596   0.33  17.206 ? 221 ILE D CG1  1 ? 
ATOM   4517 C CG2  . ILE B 1 53  ? 18.167  38.574  7.896   0.33  16.737 ? 221 ILE D CG2  1 ? 
ATOM   4518 C CD1  . ILE B 1 53  ? 15.198  39.397  6.978   0.33  17.064 ? 221 ILE D CD1  1 ? 
ATOM   4519 H H    . ILE B 1 53  ? 15.189  37.586  10.375  0.33  16.182 ? 221 ILE D H    1 c 
ATOM   4520 H HA   . ILE B 1 53  ? 17.059  36.253  8.955   0.33  16.351 ? 221 ILE D HA   1 c 
ATOM   4521 H HB   . ILE B 1 53  ? 16.635  39.044  9.164   0.33  16.857 ? 221 ILE D HB   1 c 
ATOM   4522 H HG12 . ILE B 1 53  ? 15.992  37.509  6.877   0.33  17.109 ? 221 ILE D HG12 1 c 
ATOM   4523 H HG13 . ILE B 1 53  ? 14.947  37.669  8.053   0.33  17.109 ? 221 ILE D HG13 1 c 
ATOM   4524 H HG21 . ILE B 1 53  ? 18.061  39.352  7.322   0.33  16.792 ? 221 ILE D HG21 1 c 
ATOM   4525 H HG22 . ILE B 1 53  ? 18.43   37.809  7.357   0.33  16.792 ? 221 ILE D HG22 1 c 
ATOM   4526 H HG23 . ILE B 1 53  ? 18.856  38.754  8.558   0.33  16.792 ? 221 ILE D HG23 1 c 
ATOM   4527 H HD11 . ILE B 1 53  ? 14.868  39.99   7.68    0.33  17.105 ? 221 ILE D HD11 1 c 
ATOM   4528 H HD12 . ILE B 1 53  ? 14.474  39.203  6.352   0.33  17.105 ? 221 ILE D HD12 1 c 
ATOM   4529 H HD13 . ILE B 1 53  ? 15.929  39.835  6.502   0.33  17.105 ? 221 ILE D HD13 1 c 
ATOM   4530 N N    . ALA B 1 54  ? 18.131  37.868  11.515  0.33  16.239 ? 222 ALA D N    1 ? 
ATOM   4531 C CA   . ALA B 1 54  ? 19.236  38.042  12.439  0.33  16.124 ? 222 ALA D CA   1 ? 
ATOM   4532 C C    . ALA B 1 54  ? 19.667  36.699  13.024  0.33  16.404 ? 222 ALA D C    1 ? 
ATOM   4533 O O    . ALA B 1 54  ? 20.863  36.445  13.201  0.33  17.954 ? 222 ALA D O    1 ? 
ATOM   4534 C CB   . ALA B 1 54  ? 18.84   39.025  13.528  0.33  16.252 ? 222 ALA D CB   1 ? 
ATOM   4535 H H    . ALA B 1 54  ? 17.345  38.302  11.687  0.33  15.992 ? 222 ALA D H    1 c 
ATOM   4536 H HA   . ALA B 1 54  ? 20.007  38.418  11.93   0.33  16.221 ? 222 ALA D HA   1 c 
ATOM   4537 H HB1  . ALA B 1 54  ? 18.616  39.882  13.128  0.33  16.214 ? 222 ALA D HB1  1 c 
ATOM   4538 H HB2  . ALA B 1 54  ? 18.069  38.684  14.011  0.33  16.214 ? 222 ALA D HB2  1 c 
ATOM   4539 H HB3  . ALA B 1 54  ? 19.581  39.143  14.147  0.33  16.214 ? 222 ALA D HB3  1 c 
ATOM   4540 N N    . ALA B 1 55  ? 18.69   35.833  13.312  0.33  15.997 ? 223 ALA D N    1 ? 
ATOM   4541 C CA   . ALA B 1 55  ? 18.985  34.564  13.954  0.33  16.49  ? 223 ALA D CA   1 ? 
ATOM   4542 C C    . ALA B 1 55  ? 19.422  33.505  12.937  0.33  16.777 ? 223 ALA D C    1 ? 
ATOM   4543 O O    . ALA B 1 55  ? 19.888  32.454  13.346  0.33  18.146 ? 223 ALA D O    1 ? 
ATOM   4544 C CB   . ALA B 1 55  ? 17.796  34.098  14.76   0.33  16.03  ? 223 ALA D CB   1 ? 
ATOM   4545 H H    . ALA B 1 55  ? 17.824  36.038  13.105  0.33  16.203 ? 223 ALA D H    1 c 
ATOM   4546 H HA   . ALA B 1 55  ? 19.749  34.714  14.578  0.33  16.359 ? 223 ALA D HA   1 c 
ATOM   4547 H HB1  . ALA B 1 55  ? 17.586  34.757  15.444  0.33  16.165 ? 223 ALA D HB1  1 c 
ATOM   4548 H HB2  . ALA B 1 55  ? 17.027  33.987  14.175  0.33  16.165 ? 223 ALA D HB2  1 c 
ATOM   4549 H HB3  . ALA B 1 55  ? 18.001  33.249  15.186  0.33  16.165 ? 223 ALA D HB3  1 c 
ATOM   4550 N N    . SER B 1 56  ? 19.248  33.75   11.626  0.33  16.54  ? 224 SER D N    1 ? 
ATOM   4551 C CA   . SER B 1 56  ? 19.67   32.8    10.6    0.33  15.128 ? 224 SER D CA   1 ? 
ATOM   4552 C C    . SER B 1 56  ? 21.193  32.738  10.555  0.33  14.865 ? 224 SER D C    1 ? 
ATOM   4553 O O    . SER B 1 56  ? 21.868  33.568  11.151  0.33  14.118 ? 224 SER D O    1 ? 
ATOM   4554 C CB   . SER B 1 56  ? 19.106  33.151  9.249   0.33  16.098 ? 224 SER D CB   1 ? 
ATOM   4555 O OG   . SER B 1 56  ? 19.741  34.31   8.712   0.33  15.877 ? 224 SER D OG   1 ? 
ATOM   4556 H H    . SER B 1 56  ? 18.854  34.533  11.367  0.33  16.268 ? 224 SER D H    1 c 
ATOM   4557 H HA   . SER B 1 56  ? 19.333  31.904  10.855  0.33  15.521 ? 224 SER D HA   1 c 
ATOM   4558 H HB2  . SER B 1 56  ? 19.235  32.399  8.64    0.33  15.82  ? 224 SER D HB2  1 c 
ATOM   4559 H HB3  . SER B 1 56  ? 18.148  33.315  9.332   0.33  15.82  ? 224 SER D HB3  1 c 
ATOM   4560 N N    . LYS B 1 57  ? 21.741  31.765  9.818   0.33  15.255 ? 225 LYS D N    1 ? 
ATOM   4561 C CA   . LYS B 1 57  ? 23.187  31.624  9.736   0.33  16.467 ? 225 LYS D CA   1 ? 
ATOM   4562 C C    . LYS B 1 57  ? 23.771  32.123  8.403   0.33  15.692 ? 225 LYS D C    1 ? 
ATOM   4563 O O    . LYS B 1 57  ? 24.914  31.786  8.065   0.33  18.46  ? 225 LYS D O    1 ? 
ATOM   4564 C CB   . LYS B 1 57  ? 23.558  30.171  10.04   0.33  18.592 ? 225 LYS D CB   1 ? 
ATOM   4565 C CG   . LYS B 1 57  ? 23.395  29.765  11.498  0.33  20.632 ? 225 LYS D CG   1 ? 
ATOM   4566 C CD   . LYS B 1 57  ? 23.867  28.351  11.813  0.33  21.171 ? 225 LYS D CD   1 ? 
ATOM   4567 C CE   . LYS B 1 57  ? 23.917  28.055  13.278  0.33  21.631 ? 225 LYS D CE   1 ? 
ATOM   4568 N NZ   . LYS B 1 57  ? 24.6    26.782  13.541  0.33  21.629 ? 225 LYS D NZ   1 ? 
ATOM   4569 H H    . LYS B 1 57  ? 21.207  31.181  9.36    0.33  15.423 ? 225 LYS D H    1 c 
ATOM   4570 H HA   . LYS B 1 57  ? 23.58   32.178  10.457  0.33  16.448 ? 225 LYS D HA   1 c 
ATOM   4571 H HB2  . LYS B 1 57  ? 23      29.582  9.49    0.33  18.524 ? 225 LYS D HB2  1 c 
ATOM   4572 H HB3  . LYS B 1 57  ? 24.493  30.024  9.78    0.33  18.524 ? 225 LYS D HB3  1 c 
ATOM   4573 H HG2  . LYS B 1 57  ? 23.898  30.399  12.054  0.33  20.264 ? 225 LYS D HG2  1 c 
ATOM   4574 H HG3  . LYS B 1 57  ? 22.446  29.845  11.738  0.33  20.264 ? 225 LYS D HG3  1 c 
ATOM   4575 H HD2  . LYS B 1 57  ? 23.261  27.711  11.379  0.33  21.153 ? 225 LYS D HD2  1 c 
ATOM   4576 H HD3  . LYS B 1 57  ? 24.762  28.222  11.431  0.33  21.153 ? 225 LYS D HD3  1 c 
ATOM   4577 H HE2  . LYS B 1 57  ? 24.39   28.77   13.74   0.33  21.525 ? 225 LYS D HE2  1 c 
ATOM   4578 H HE3  . LYS B 1 57  ? 23.011  28.008  13.634  0.33  21.525 ? 225 LYS D HE3  1 c 
ATOM   4579 H HZ1  . LYS B 1 57  ? 25.449  26.82   13.225  0.33  21.63  ? 225 LYS D HZ1  1 c 
ATOM   4580 H HZ2  . LYS B 1 57  ? 24.159  26.107  13.128  0.33  21.63  ? 225 LYS D HZ2  1 c 
ATOM   4581 H HZ3  . LYS B 1 57  ? 24.621  26.624  14.433  0.33  21.63  ? 225 LYS D HZ3  1 c 
ATOM   4582 N N    . PHE B 1 58  ? 23.036  32.96   7.661   0.33  14.79  ? 226 PHE D N    1 ? 
ATOM   4583 C CA   . PHE B 1 58  ? 23.54   33.514  6.407   0.33  13.36  ? 226 PHE D CA   1 ? 
ATOM   4584 C C    . PHE B 1 58  ? 24.557  34.615  6.682   0.33  14.129 ? 226 PHE D C    1 ? 
ATOM   4585 O O    . PHE B 1 58  ? 24.44   35.335  7.669   0.33  13.619 ? 226 PHE D O    1 ? 
ATOM   4586 C CB   . PHE B 1 58  ? 22.394  34.03   5.535   0.33  12.816 ? 226 PHE D CB   1 ? 
ATOM   4587 C CG   . PHE B 1 58  ? 21.413  32.951  5.1     0.33  11.915 ? 226 PHE D CG   1 ? 
ATOM   4588 C CD1  . PHE B 1 58  ? 21.691  32.145  4.014   0.33  11.506 ? 226 PHE D CD1  1 ? 
ATOM   4589 C CD2  . PHE B 1 58  ? 20.242  32.73   5.806   0.33  11.552 ? 226 PHE D CD2  1 ? 
ATOM   4590 C CE1  . PHE B 1 58  ? 20.812  31.145  3.618   0.33  11.743 ? 226 PHE D CE1  1 ? 
ATOM   4591 C CE2  . PHE B 1 58  ? 19.375  31.725  5.437   0.33  11.777 ? 226 PHE D CE2  1 ? 
ATOM   4592 C CZ   . PHE B 1 58  ? 19.656  30.926  4.346   0.33  11.505 ? 226 PHE D CZ   1 ? 
ATOM   4593 H H    . PHE B 1 58  ? 22.198  33.194  7.943   0.33  14.662 ? 226 PHE D H    1 c 
ATOM   4594 H HA   . PHE B 1 58  ? 23.999  32.784  5.912   0.33  13.663 ? 226 PHE D HA   1 c 
ATOM   4595 H HB2  . PHE B 1 58  ? 21.906  34.72   6.037   0.33  12.725 ? 226 PHE D HB2  1 c 
ATOM   4596 H HB3  . PHE B 1 58  ? 22.777  34.453  4.735   0.33  12.725 ? 226 PHE D HB3  1 c 
ATOM   4597 H HD1  . PHE B 1 58  ? 22.486  32.285  3.525   0.33  11.661 ? 226 PHE D HD1  1 c 
ATOM   4598 H HD2  . PHE B 1 58  ? 20.049  33.26   6.563   0.33  11.692 ? 226 PHE D HD2  1 c 
ATOM   4599 H HE1  . PHE B 1 58  ? 21.015  30.602  2.873   0.33  11.637 ? 226 PHE D HE1  1 c 
ATOM   4600 H HE2  . PHE B 1 58  ? 18.578  31.591  5.925   0.33  11.664 ? 226 PHE D HE2  1 c 
ATOM   4601 H HZ   . PHE B 1 58  ? 19.048  30.254  4.081   0.33  11.625 ? 226 PHE D HZ   1 c 
ATOM   4602 N N    . ASP B 1 59  ? 25.524  34.765  5.762   0.33  14.914 ? 227 ASP D N    1 ? 
ATOM   4603 C CA   . ASP B 1 59  ? 26.58   35.757  5.89    0.33  15.777 ? 227 ASP D CA   1 ? 
ATOM   4604 C C    . ASP B 1 59  ? 26.104  37.142  5.468   0.33  15.687 ? 227 ASP D C    1 ? 
ATOM   4605 O O    . ASP B 1 59  ? 26.713  38.155  5.81    0.33  15.645 ? 227 ASP D O    1 ? 
ATOM   4606 C CB   . ASP B 1 59  ? 27.78   35.392  5.038   0.33  16.728 ? 227 ASP D CB   1 ? 
ATOM   4607 C CG   . ASP B 1 59  ? 28.532  34.17   5.526   0.33  16.782 ? 227 ASP D CG   1 ? 
ATOM   4608 O OD1  . ASP B 1 59  ? 28.322  33.821  6.719   0.33  16.876 ? 227 ASP D OD1  1 ? 
ATOM   4609 O OD2  . ASP B 1 59  ? 29.268  33.585  4.706   0.33  15.779 ? 227 ASP D OD2  1 ? 
ATOM   4610 H H    . ASP B 1 59  ? 25.521  34.223  5.026   0.33  14.911 ? 227 ASP D H    1 c 
ATOM   4611 H HA   . ASP B 1 59  ? 26.862  35.791  6.832   0.33  15.758 ? 227 ASP D HA   1 c 
ATOM   4612 H HB2  . ASP B 1 59  ? 27.48   35.223  4.121   0.33  16.518 ? 227 ASP D HB2  1 c 
ATOM   4613 H HB3  . ASP B 1 59  ? 28.401  36.15   5.021   0.33  16.518 ? 227 ASP D HB3  1 c 
ATOM   4614 N N    . LEU B 1 60  ? 25.043  37.189  4.67    0.33  13.285 ? 228 LEU D N    1 ? 
ATOM   4615 C CA   . LEU B 1 60  ? 24.63   38.444  4.062   0.33  13.426 ? 228 LEU D CA   1 ? 
ATOM   4616 C C    . LEU B 1 60  ? 23.122  38.388  3.904   0.33  12.924 ? 228 LEU D C    1 ? 
ATOM   4617 O O    . LEU B 1 60  ? 22.599  37.329  3.602   0.33  11.992 ? 228 LEU D O    1 ? 
ATOM   4618 C CB   . LEU B 1 60  ? 25.336  38.665  2.725   0.33  13.542 ? 228 LEU D CB   1 ? 
ATOM   4619 C CG   . LEU B 1 60  ? 25.001  39.964  1.982   0.33  13.753 ? 228 LEU D CG   1 ? 
ATOM   4620 C CD1  . LEU B 1 60  ? 26.142  40.353  1.058   0.33  14.008 ? 228 LEU D CD1  1 ? 
ATOM   4621 C CD2  . LEU B 1 60  ? 23.733  39.862  1.168   0.33  14.227 ? 228 LEU D CD2  1 ? 
ATOM   4622 H H    . LEU B 1 60  ? 24.564  36.429  4.498   0.33  13.856 ? 228 LEU D H    1 c 
ATOM   4623 H HA   . LEU B 1 60  ? 24.86   39.183  4.681   0.33  13.326 ? 228 LEU D HA   1 c 
ATOM   4624 H HB2  . LEU B 1 60  ? 26.307  38.642  2.885   0.33  13.563 ? 228 LEU D HB2  1 c 
ATOM   4625 H HB3  . LEU B 1 60  ? 25.118  37.907  2.136   0.33  13.563 ? 228 LEU D HB3  1 c 
ATOM   4626 H HG   . LEU B 1 60  ? 24.884  40.686  2.652   0.33  13.849 ? 228 LEU D HG   1 c 
ATOM   4627 H HD11 . LEU B 1 60  ? 26.953  40.478  1.579   0.33  13.932 ? 228 LEU D HD11 1 c 
ATOM   4628 H HD12 . LEU B 1 60  ? 25.921  41.181  0.6     0.33  13.932 ? 228 LEU D HD12 1 c 
ATOM   4629 H HD13 . LEU B 1 60  ? 26.284  39.649  0.403   0.33  13.932 ? 228 LEU D HD13 1 c 
ATOM   4630 H HD21 . LEU B 1 60  ? 22.987  39.654  1.754   0.33  14.085 ? 228 LEU D HD21 1 c 
ATOM   4631 H HD22 . LEU B 1 60  ? 23.829  39.159  0.504   0.33  14.085 ? 228 LEU D HD22 1 c 
ATOM   4632 H HD23 . LEU B 1 60  ? 23.566  40.708  0.72    0.33  14.085 ? 228 LEU D HD23 1 c 
ATOM   4633 N N    . ALA B 1 61  ? 22.465  39.517  4.176   0.33  12.292 ? 229 ALA D N    1 ? 
ATOM   4634 C CA   . ALA B 1 61  ? 21.041  39.659  3.95    0.33  12.584 ? 229 ALA D CA   1 ? 
ATOM   4635 C C    . ALA B 1 61  ? 20.774  40.858  3.042   0.33  12.678 ? 229 ALA D C    1 ? 
ATOM   4636 O O    . ALA B 1 61  ? 21.377  41.924  3.194   0.33  11.515 ? 229 ALA D O    1 ? 
ATOM   4637 C CB   . ALA B 1 61  ? 20.322  39.794  5.254   0.33  12.45  ? 229 ALA D CB   1 ? 
ATOM   4638 H H    . ALA B 1 61  ? 22.927  40.228  4.517   0.33  12.506 ? 229 ALA D H    1 c 
ATOM   4639 H HA   . ALA B 1 61  ? 20.719  38.839  3.483   0.33  12.519 ? 229 ALA D HA   1 c 
ATOM   4640 H HB1  . ALA B 1 61  ? 20.476  39.002  5.796   0.33  12.49  ? 229 ALA D HB1  1 c 
ATOM   4641 H HB2  . ALA B 1 61  ? 20.648  40.577  5.728   0.33  12.49  ? 229 ALA D HB2  1 c 
ATOM   4642 H HB3  . ALA B 1 61  ? 19.368  39.891  5.092   0.33  12.49  ? 229 ALA D HB3  1 c 
ATOM   4643 N N    . ILE B 1 62  ? 19.846  40.64   2.11    0.33  11.96  ? 230 ILE D N    1 ? 
ATOM   4644 C CA   . ILE B 1 62  ? 19.282  41.7    1.299   0.33  12.886 ? 230 ILE D CA   1 ? 
ATOM   4645 C C    . ILE B 1 62  ? 17.861  41.96   1.8     0.33  13.473 ? 230 ILE D C    1 ? 
ATOM   4646 O O    . ILE B 1 62  ? 17.013  41.067  1.755   0.33  13.79  ? 230 ILE D O    1 ? 
ATOM   4647 C CB   . ILE B 1 62  ? 19.289  41.331  -0.198  0.33  12.298 ? 230 ILE D CB   1 ? 
ATOM   4648 C CG1  . ILE B 1 62  ? 20.685  40.954  -0.717  0.33  13.073 ? 230 ILE D CG1  1 ? 
ATOM   4649 C CG2  . ILE B 1 62  ? 18.681  42.472  -1.013  0.33  11.804 ? 230 ILE D CG2  1 ? 
ATOM   4650 C CD1  . ILE B 1 62  ? 20.695  40.192  -2.033  0.33  13.259 ? 230 ILE D CD1  1 ? 
ATOM   4651 H H    . ILE B 1 62  ? 19.552  39.785  1.975   0.33  12.334 ? 230 ILE D H    1 c 
ATOM   4652 H HA   . ILE B 1 62  ? 19.815  42.509  1.425   0.33  12.696 ? 230 ILE D HA   1 c 
ATOM   4653 H HB   . ILE B 1 62  ? 18.714  40.548  -0.31   0.33  12.451 ? 230 ILE D HB   1 c 
ATOM   4654 H HG12 . ILE B 1 62  ? 21.207  41.775  -0.828  0.33  12.935 ? 230 ILE D HG12 1 c 
ATOM   4655 H HG13 . ILE B 1 62  ? 21.132  40.409  -0.038  0.33  12.935 ? 230 ILE D HG13 1 c 
ATOM   4656 H HG21 . ILE B 1 62  ? 18.696  42.242  -1.957  0.33  11.947 ? 230 ILE D HG21 1 c 
ATOM   4657 H HG22 . ILE B 1 62  ? 19.196  43.284  -0.871  0.33  11.947 ? 230 ILE D HG22 1 c 
ATOM   4658 H HG23 . ILE B 1 62  ? 17.762  42.62   -0.732  0.33  11.947 ? 230 ILE D HG23 1 c 
ATOM   4659 H HD11 . ILE B 1 62  ? 20.221  39.346  -1.925  0.33  13.204 ? 230 ILE D HD11 1 c 
ATOM   4660 H HD12 . ILE B 1 62  ? 21.617  40.014  -2.301  0.33  13.204 ? 230 ILE D HD12 1 c 
ATOM   4661 H HD13 . ILE B 1 62  ? 20.255  40.724  -2.723  0.33  13.204 ? 230 ILE D HD13 1 c 
ATOM   4662 N N    . VAL B 1 63  ? 17.611  43.187  2.265   0.33  13.14  ? 231 VAL D N    1 ? 
ATOM   4663 C CA   . VAL B 1 63  ? 16.301  43.596  2.749   0.33  13.843 ? 231 VAL D CA   1 ? 
ATOM   4664 C C    . VAL B 1 63  ? 15.939  44.976  2.19    0.33  14.241 ? 231 VAL D C    1 ? 
ATOM   4665 O O    . VAL B 1 63  ? 16.793  45.692  1.665   0.33  14.038 ? 231 VAL D O    1 ? 
ATOM   4666 C CB   . VAL B 1 63  ? 16.3    43.58   4.289   0.33  14.428 ? 231 VAL D CB   1 ? 
ATOM   4667 C CG1  . VAL B 1 63  ? 16.592  42.191  4.83    0.33  14.297 ? 231 VAL D CG1  1 ? 
ATOM   4668 C CG2  . VAL B 1 63  ? 17.271  44.589  4.895   0.33  14.446 ? 231 VAL D CG2  1 ? 
ATOM   4669 H H    . VAL B 1 63  ? 18.29   43.798  2.281   0.33  13.375 ? 231 VAL D H    1 c 
ATOM   4670 H HA   . VAL B 1 63  ? 15.641  42.95   2.432   0.33  13.879 ? 231 VAL D HA   1 c 
ATOM   4671 H HB   . VAL B 1 63  ? 15.391  43.829  4.579   0.33  14.297 ? 231 VAL D HB   1 c 
ATOM   4672 H HG11 . VAL B 1 63  ? 17.468  41.9    4.525   0.33  14.336 ? 231 VAL D HG11 1 c 
ATOM   4673 H HG12 . VAL B 1 63  ? 15.917  41.569  4.512   0.33  14.336 ? 231 VAL D HG12 1 c 
ATOM   4674 H HG13 . VAL B 1 63  ? 16.58   42.211  5.802   0.33  14.336 ? 231 VAL D HG13 1 c 
ATOM   4675 H HG21 . VAL B 1 63  ? 17.233  44.535  5.865   0.33  14.441 ? 231 VAL D HG21 1 c 
ATOM   4676 H HG22 . VAL B 1 63  ? 17.028  45.486  4.612   0.33  14.441 ? 231 VAL D HG22 1 c 
ATOM   4677 H HG23 . VAL B 1 63  ? 18.175  44.39   4.596   0.33  14.441 ? 231 VAL D HG23 1 c 
ATOM   4678 N N    . GLU B 1 64  ? 14.657  45.349  2.28    0.33  14.649 ? 232 GLU D N    1 ? 
ATOM   4679 C CA   . GLU B 1 64  ? 14.251  46.699  1.917   0.33  16.651 ? 232 GLU D CA   1 ? 
ATOM   4680 C C    . GLU B 1 64  ? 14.728  47.692  2.972   0.33  15.95  ? 232 GLU D C    1 ? 
ATOM   4681 O O    . GLU B 1 64  ? 15.176  47.308  4.038   0.33  15.133 ? 232 GLU D O    1 ? 
ATOM   4682 C CB   . GLU B 1 64  ? 12.742  46.887  1.788   0.33  18.315 ? 232 GLU D CB   1 ? 
ATOM   4683 C CG   . GLU B 1 64  ? 12.107  46.02   0.718   0.33  20.198 ? 232 GLU D CG   1 ? 
ATOM   4684 C CD   . GLU B 1 64  ? 10.955  46.754  0.054   0.33  23.735 ? 232 GLU D CD   1 ? 
ATOM   4685 O OE1  . GLU B 1 64  ? 11.007  46.795  -1.186  0.33  20.762 ? 232 GLU D OE1  1 ? 
ATOM   4686 O OE2  . GLU B 1 64  ? 10.027  47.251  0.752   0.33  24.789 ? 232 GLU D OE2  1 ? 
ATOM   4687 H H    . GLU B 1 64  ? 14.027  44.755  2.572   0.33  14.975 ? 232 GLU D H    1 c 
ATOM   4688 H HA   . GLU B 1 64  ? 14.676  46.929  1.051   0.33  16.395 ? 232 GLU D HA   1 c 
ATOM   4689 H HB2  . GLU B 1 64  ? 12.325  46.683  2.651   0.33  18.328 ? 232 GLU D HB2  1 c 
ATOM   4690 H HB3  . GLU B 1 64  ? 12.558  47.828  1.583   0.33  18.328 ? 232 GLU D HB3  1 c 
ATOM   4691 H HG2  . GLU B 1 64  ? 12.777  45.789  0.039   0.33  20.495 ? 232 GLU D HG2  1 c 
ATOM   4692 H HG3  . GLU B 1 64  ? 11.771  45.191  1.122   0.33  20.495 ? 232 GLU D HG3  1 c 
ATOM   4693 N N    . LEU B 1 65  ? 14.663  48.98   2.628   0.33  15.896 ? 233 LEU D N    1 ? 
ATOM   4694 C CA   . LEU B 1 65  ? 14.907  50.053  3.58    0.33  16.182 ? 233 LEU D CA   1 ? 
ATOM   4695 C C    . LEU B 1 65  ? 13.788  50.105  4.614   0.33  16.237 ? 233 LEU D C    1 ? 
ATOM   4696 O O    . LEU B 1 65  ? 14.02   50.637  5.696   0.33  19.305 ? 233 LEU D O    1 ? 
ATOM   4697 C CB   . LEU B 1 65  ? 15.018  51.394  2.864   0.33  15.128 ? 233 LEU D CB   1 ? 
ATOM   4698 C CG   . LEU B 1 65  ? 16.203  51.525  1.906   0.33  15.14  ? 233 LEU D CG   1 ? 
ATOM   4699 C CD1  . LEU B 1 65  ? 15.956  52.63   0.905   0.33  14.763 ? 233 LEU D CD1  1 ? 
ATOM   4700 C CD2  . LEU B 1 65  ? 17.484  51.756  2.696   0.33  14.723 ? 233 LEU D CD2  1 ? 
ATOM   4701 H H    . LEU B 1 65  ? 14.459  49.198  1.764   0.33  15.973 ? 233 LEU D H    1 c 
ATOM   4702 H HA   . LEU B 1 65  ? 15.759  49.864  4.048   0.33  15.939 ? 233 LEU D HA   1 c 
ATOM   4703 H HB2  . LEU B 1 65  ? 14.187  51.542  2.355   0.33  15.366 ? 233 LEU D HB2  1 c 
ATOM   4704 H HB3  . LEU B 1 65  ? 15.087  52.103  3.545   0.33  15.366 ? 233 LEU D HB3  1 c 
ATOM   4705 H HG   . LEU B 1 65  ? 16.295  50.672  1.409   0.33  14.989 ? 233 LEU D HG   1 c 
ATOM   4706 H HD11 . LEU B 1 65  ? 15.148  52.437  0.401   0.33  14.874 ? 233 LEU D HD11 1 c 
ATOM   4707 H HD12 . LEU B 1 65  ? 16.711  52.69   0.295   0.33  14.874 ? 233 LEU D HD12 1 c 
ATOM   4708 H HD13 . LEU B 1 65  ? 15.852  53.475  1.373   0.33  14.874 ? 233 LEU D HD13 1 c 
ATOM   4709 H HD21 . LEU B 1 65  ? 17.644  51      3.285   0.33  14.844 ? 233 LEU D HD21 1 c 
ATOM   4710 H HD22 . LEU B 1 65  ? 17.398  52.566  3.226   0.33  14.844 ? 233 LEU D HD22 1 c 
ATOM   4711 H HD23 . LEU B 1 65  ? 18.232  51.85   2.082   0.33  14.844 ? 233 LEU D HD23 1 c 
ATOM   4712 N N    . VAL B 1 66  ? 12.609  49.577  4.261   0.33  16.82  ? 234 VAL D N    1 ? 
ATOM   4713 C CA   . VAL B 1 66  ? 11.377  49.768  5.02    0.33  18.504 ? 234 VAL D CA   1 ? 
ATOM   4714 C C    . VAL B 1 66  ? 10.738  48.416  5.308   0.33  19.247 ? 234 VAL D C    1 ? 
ATOM   4715 O O    . VAL B 1 66  ? 10.876  47.478  4.531   0.33  17.418 ? 234 VAL D O    1 ? 
ATOM   4716 C CB   . VAL B 1 66  ? 10.381  50.687  4.284   0.33  18.475 ? 234 VAL D CB   1 ? 
ATOM   4717 C CG1  . VAL B 1 66  ? 10.894  52.112  4.263   0.33  18.65  ? 234 VAL D CG1  1 ? 
ATOM   4718 C CG2  . VAL B 1 66  ? 10.069  50.213  2.87    0.33  18.375 ? 234 VAL D CG2  1 ? 
ATOM   4719 H H    . VAL B 1 66  ? 12.573  49.069  3.502   0.33  17.043 ? 234 VAL D H    1 c 
ATOM   4720 H HA   . VAL B 1 66  ? 11.607  50.186  5.873   0.33  18.291 ? 234 VAL D HA   1 c 
ATOM   4721 H HB   . VAL B 1 66  ? 9.54    50.676  4.799   0.33  18.494 ? 234 VAL D HB   1 c 
ATOM   4722 H HG11 . VAL B 1 66  ? 11.753  52.141  3.809   0.33  18.598 ? 234 VAL D HG11 1 c 
ATOM   4723 H HG12 . VAL B 1 66  ? 11      52.433  5.174   0.33  18.598 ? 234 VAL D HG12 1 c 
ATOM   4724 H HG13 . VAL B 1 66  ? 10.261  52.679  3.792   0.33  18.598 ? 234 VAL D HG13 1 c 
ATOM   4725 H HG21 . VAL B 1 66  ? 9.438   50.824  2.455   0.33  18.404 ? 234 VAL D HG21 1 c 
ATOM   4726 H HG22 . VAL B 1 66  ? 9.681   49.322  2.904   0.33  18.404 ? 234 VAL D HG22 1 c 
ATOM   4727 H HG23 . VAL B 1 66  ? 10.888  50.189  2.347   0.33  18.404 ? 234 VAL D HG23 1 c 
ATOM   4728 N N    . ARG B 1 67  ? 10.038  48.336  6.438   0.33  20.304 ? 235 ARG D N    1 ? 
ATOM   4729 C CA   . ARG B 1 67  ? 9.446   47.083  6.87    0.33  21.515 ? 235 ARG D CA   1 ? 
ATOM   4730 C C    . ARG B 1 67  ? 8.084   46.875  6.203   0.33  23.186 ? 235 ARG D C    1 ? 
ATOM   4731 O O    . ARG B 1 67  ? 7.514   45.791  6.316   0.33  24.344 ? 235 ARG D O    1 ? 
ATOM   4732 C CB   . ARG B 1 67  ? 9.303   47.098  8.396   0.33  21.806 ? 235 ARG D CB   1 ? 
ATOM   4733 C CG   . ARG B 1 67  ? 8.134   47.915  8.927   0.33  21.899 ? 235 ARG D CG   1 ? 
ATOM   4734 C CD   . ARG B 1 67  ? 8.27    48.163  10.434  0.33  21.098 ? 235 ARG D CD   1 ? 
ATOM   4735 N NE   . ARG B 1 67  ? 9.371   49.088  10.74   0.33  20.185 ? 235 ARG D NE   1 ? 
ATOM   4736 C CZ   . ARG B 1 67  ? 10.478  48.815  11.422  0.33  21.39  ? 235 ARG D CZ   1 ? 
ATOM   4737 N NH1  . ARG B 1 67  ? 10.687  47.617  11.939  0.33  22.495 ? 235 ARG D NH1  1 ? 
ATOM   4738 N NH2  . ARG B 1 67  ? 11.406  49.735  11.559  0.33  22.182 ? 235 ARG D NH2  1 ? 
ATOM   4739 H H    . ARG B 1 67  ? 9.924   49.082  6.954   0.33  20.31  ? 235 ARG D H    1 c 
ATOM   4740 H HA   . ARG B 1 67  ? 10.05   46.343  6.605   0.33  21.616 ? 235 ARG D HA   1 c 
ATOM   4741 H HB2  . ARG B 1 67  ? 9.204   46.173  8.708   0.33  21.761 ? 235 ARG D HB2  1 c 
ATOM   4742 H HB3  . ARG B 1 67  ? 10.132  47.452  8.782   0.33  21.761 ? 235 ARG D HB3  1 c 
ATOM   4743 H HG2  . ARG B 1 67  ? 8.099   48.778  8.46    0.33  21.695 ? 235 ARG D HG2  1 c 
ATOM   4744 H HG3  . ARG B 1 67  ? 7.294   47.436  8.754   0.33  21.695 ? 235 ARG D HG3  1 c 
ATOM   4745 H HD2  . ARG B 1 67  ? 7.432   48.534  10.777  0.33  21.053 ? 235 ARG D HD2  1 c 
ATOM   4746 H HD3  . ARG B 1 67  ? 8.431   47.31   10.888  0.33  21.053 ? 235 ARG D HD3  1 c 
ATOM   4747 H HE   . ARG B 1 67  ? 9.294   49.904  10.445  0.33  20.674 ? 235 ARG D HE   1 c 
ATOM   4748 H HH11 . ARG B 1 67  ? 10.082  46.982  11.833  0.33  22.149 ? 235 ARG D HH11 1 c 
ATOM   4749 H HH12 . ARG B 1 67  ? 11.432  47.456  12.387  0.33  22.149 ? 235 ARG D HH12 1 c 
ATOM   4750 H HH21 . ARG B 1 67  ? 11.291  50.533  11.195  0.33  21.936 ? 235 ARG D HH21 1 c 
ATOM   4751 H HH22 . ARG B 1 67  ? 12.141  49.553  12.015  0.33  21.936 ? 235 ARG D HH22 1 c 
ATOM   4752 N N    . ASP B 1 68  ? 7.568   47.904  5.515   0.33  25.145 ? 236 ASP D N    1 ? 
ATOM   4753 C CA   . ASP B 1 68  ? 6.165   47.938  5.132   0.33  26.31  ? 236 ASP D CA   1 ? 
ATOM   4754 C C    . ASP B 1 68  ? 5.97    48.408  3.692   0.33  28.093 ? 236 ASP D C    1 ? 
ATOM   4755 O O    . ASP B 1 68  ? 4.845   48.712  3.297   0.33  29.796 ? 236 ASP D O    1 ? 
ATOM   4756 C CB   . ASP B 1 68  ? 5.38    48.846  6.066   0.33  26.598 ? 236 ASP D CB   1 ? 
ATOM   4757 C CG   . ASP B 1 68  ? 5.855   50.292  6.116   0.33  26.994 ? 236 ASP D CG   1 ? 
ATOM   4758 O OD1  . ASP B 1 68  ? 6.835   50.621  5.414   0.33  25.555 ? 236 ASP D OD1  1 ? 
ATOM   4759 O OD2  . ASP B 1 68  ? 5.244   51.083  6.858   0.33  27.762 ? 236 ASP D OD2  1 ? 
ATOM   4760 H H    . ASP B 1 68  ? 8.107   48.603  5.28    0.33  24.916 ? 236 ASP D H    1 c 
ATOM   4761 H HA   . ASP B 1 68  ? 5.801   47.027  5.216   0.33  26.447 ? 236 ASP D HA   1 c 
ATOM   4762 H HB2  . ASP B 1 68  ? 4.44    48.843  5.789   0.33  26.622 ? 236 ASP D HB2  1 c 
ATOM   4763 H HB3  . ASP B 1 68  ? 5.428   48.478  6.974   0.33  26.622 ? 236 ASP D HB3  1 c 
ATOM   4764 N N    . GLY B 1 69  ? 7.054   48.507  2.918   0.33  27.172 ? 237 GLY D N    1 ? 
ATOM   4765 C CA   . GLY B 1 69  ? 6.955   48.913  1.525   0.33  27.625 ? 237 GLY D CA   1 ? 
ATOM   4766 C C    . GLY B 1 69  ? 6.586   50.388  1.369   0.33  27.705 ? 237 GLY D C    1 ? 
ATOM   4767 O O    . GLY B 1 69  ? 6.256   50.847  0.276   0.33  29.287 ? 237 GLY D O    1 ? 
ATOM   4768 H H    . GLY B 1 69  ? 7.877   48.316  3.267   0.33  27.491 ? 237 GLY D H    1 c 
ATOM   4769 H HA2  . GLY B 1 69  ? 7.818   48.744  1.081   0.33  27.534 ? 237 GLY D HA2  1 c 
ATOM   4770 H HA3  . GLY B 1 69  ? 6.273   48.358  1.079   0.33  27.534 ? 237 GLY D HA3  1 c 
ATOM   4771 N N    . SER B 1 70  ? 6.618   51.131  2.479   0.33  28.217 ? 238 SER D N    1 ? 
ATOM   4772 C CA   . SER B 1 70  ? 6.209   52.526  2.468   0.33  28.47  ? 238 SER D CA   1 ? 
ATOM   4773 C C    . SER B 1 70  ? 7.245   53.383  3.2     0.33  27.132 ? 238 SER D C    1 ? 
ATOM   4774 O O    . SER B 1 70  ? 8.332   53.623  2.681   0.33  25.726 ? 238 SER D O    1 ? 
ATOM   4775 C CB   . SER B 1 70  ? 4.81    52.667  3.034   0.33  30.56  ? 238 SER D CB   1 ? 
ATOM   4776 O OG   . SER B 1 70  ? 4.347   54.011  2.981   0.33  29.814 ? 238 SER D OG   1 ? 
ATOM   4777 H H    . SER B 1 70  ? 6.902   50.759  3.263   0.33  28.151 ? 238 SER D H    1 c 
ATOM   4778 H HA   . SER B 1 70  ? 6.186   52.824  1.523   0.33  28.543 ? 238 SER D HA   1 c 
ATOM   4779 H HB2  . SER B 1 70  ? 4.201   52.096  2.528   0.33  29.898 ? 238 SER D HB2  1 c 
ATOM   4780 H HB3  . SER B 1 70  ? 4.808   52.362  3.961   0.33  29.898 ? 238 SER D HB3  1 c 
ATOM   4781 N N    . SER B 1 71  ? 6.957   53.812  4.429   0.33  27.944 ? 239 SER D N    1 ? 
ATOM   4782 C CA   . SER B 1 71  ? 7.868   54.729  5.095   0.33  27.154 ? 239 SER D CA   1 ? 
ATOM   4783 C C    . SER B 1 71  ? 8.307   54.222  6.464   0.33  24.967 ? 239 SER D C    1 ? 
ATOM   4784 O O    . SER B 1 71  ? 8.85    54.994  7.252   0.33  23.326 ? 239 SER D O    1 ? 
ATOM   4785 C CB   . SER B 1 71  ? 7.255   56.09   5.216   0.33  28.794 ? 239 SER D CB   1 ? 
ATOM   4786 O OG   . SER B 1 71  ? 6.066   56.043  5.993   0.33  31.649 ? 239 SER D OG   1 ? 
ATOM   4787 H H    . SER B 1 71  ? 6.196   53.538  4.855   0.33  27.57  ? 239 SER D H    1 c 
ATOM   4788 H HA   . SER B 1 71  ? 8.678   54.809  4.53    0.33  27.185 ? 239 SER D HA   1 c 
ATOM   4789 H HB2  . SER B 1 71  ? 7.894   56.696  5.635   0.33  29.056 ? 239 SER D HB2  1 c 
ATOM   4790 H HB3  . SER B 1 71  ? 7.047   56.431  4.325   0.33  29.056 ? 239 SER D HB3  1 c 
ATOM   4791 N N    . GLY B 1 72  ? 8.08    52.933  6.744   0.33  24.914 ? 240 GLY D N    1 ? 
ATOM   4792 C CA   . GLY B 1 72  ? 8.504   52.332  8       0.33  23.235 ? 240 GLY D CA   1 ? 
ATOM   4793 C C    . GLY B 1 72  ? 9.965   51.888  7.947   0.33  24.91  ? 240 GLY D C    1 ? 
ATOM   4794 O O    . GLY B 1 72  ? 10.256  50.692  7.926   0.33  22.367 ? 240 GLY D O    1 ? 
ATOM   4795 H H    . GLY B 1 72  ? 7.646   52.412  6.131   0.33  24.538 ? 240 GLY D H    1 c 
ATOM   4796 H HA2  . GLY B 1 72  ? 8.385   52.987  8.727   0.33  23.993 ? 240 GLY D HA2  1 c 
ATOM   4797 H HA3  . GLY B 1 72  ? 7.93    51.554  8.195   0.33  23.993 ? 240 GLY D HA3  1 c 
ATOM   4798 N N    . TYR B 1 73  ? 10.877  52.87   7.957   0.33  25.376 ? 241 TYR D N    1 ? 
ATOM   4799 C CA   . TYR B 1 73  ? 12.291  52.614  7.768   0.33  24.741 ? 241 TYR D CA   1 ? 
ATOM   4800 C C    . TYR B 1 73  ? 12.832  51.751  8.903   0.33  23.498 ? 241 TYR D C    1 ? 
ATOM   4801 O O    . TYR B 1 73  ? 12.597  52.021  10.074  0.33  24.645 ? 241 TYR D O    1 ? 
ATOM   4802 C CB   . TYR B 1 73  ? 13.049  53.941  7.666   0.33  24.808 ? 241 TYR D CB   1 ? 
ATOM   4803 C CG   . TYR B 1 73  ? 12.809  54.64   6.339   0.33  24.438 ? 241 TYR D CG   1 ? 
ATOM   4804 C CD1  . TYR B 1 73  ? 13.512  54.257  5.201   0.33  25.164 ? 241 TYR D CD1  1 ? 
ATOM   4805 C CD2  . TYR B 1 73  ? 11.86   55.643  6.211   0.33  25.202 ? 241 TYR D CD2  1 ? 
ATOM   4806 C CE1  . TYR B 1 73  ? 13.268  54.839  3.976   0.33  24.53  ? 241 TYR D CE1  1 ? 
ATOM   4807 C CE2  . TYR B 1 73  ? 11.602  56.238  4.986   0.33  24.71  ? 241 TYR D CE2  1 ? 
ATOM   4808 C CZ   . TYR B 1 73  ? 12.326  55.846  3.872   0.33  24.863 ? 241 TYR D CZ   1 ? 
ATOM   4809 O OH   . TYR B 1 73  ? 12.152  56.4    2.643   0.33  25.601 ? 241 TYR D OH   1 ? 
ATOM   4810 H H    . TYR B 1 73  ? 10.601  53.731  8.087   0.33  25.12  ? 241 TYR D H    1 c 
ATOM   4811 H HA   . TYR B 1 73  ? 12.407  52.119  6.913   0.33  24.643 ? 241 TYR D HA   1 c 
ATOM   4812 H HB2  . TYR B 1 73  ? 12.758  54.529  8.398   0.33  24.708 ? 241 TYR D HB2  1 c 
ATOM   4813 H HB3  . TYR B 1 73  ? 14.01   53.765  7.769   0.33  24.708 ? 241 TYR D HB3  1 c 
ATOM   4814 H HD1  . TYR B 1 73  ? 14.151  53.566  5.263   0.33  24.847 ? 241 TYR D HD1  1 c 
ATOM   4815 H HD2  . TYR B 1 73  ? 11.359  55.907  6.967   0.33  24.908 ? 241 TYR D HD2  1 c 
ATOM   4816 H HE1  . TYR B 1 73  ? 13.764  54.577  3.219   0.33  24.76  ? 241 TYR D HE1  1 c 
ATOM   4817 H HE2  . TYR B 1 73  ? 10.964  56.928  4.918   0.33  24.861 ? 241 TYR D HE2  1 c 
ATOM   4818 N N    . PHE B 1 74  ? 13.628  50.739  8.554   0.33  22.84  ? 242 PHE D N    1 ? 
ATOM   4819 C CA   . PHE B 1 74  ? 14.47   50.091  9.549   0.33  22.028 ? 242 PHE D CA   1 ? 
ATOM   4820 C C    . PHE B 1 74  ? 15.456  51.114  10.108  0.33  22.19  ? 242 PHE D C    1 ? 
ATOM   4821 O O    . PHE B 1 74  ? 16.011  51.925  9.378   0.33  21.043 ? 242 PHE D O    1 ? 
ATOM   4822 C CB   . PHE B 1 74  ? 15.208  48.868  9.001   0.33  21.046 ? 242 PHE D CB   1 ? 
ATOM   4823 C CG   . PHE B 1 74  ? 14.28   47.749  8.548   0.33  19.775 ? 242 PHE D CG   1 ? 
ATOM   4824 C CD1  . PHE B 1 74  ? 13.501  47.058  9.475   0.33  19.006 ? 242 PHE D CD1  1 ? 
ATOM   4825 C CD2  . PHE B 1 74  ? 14.185  47.397  7.2     0.33  19.923 ? 242 PHE D CD2  1 ? 
ATOM   4826 C CE1  . PHE B 1 74  ? 12.66   46.037  9.064   0.33  18.197 ? 242 PHE D CE1  1 ? 
ATOM   4827 C CE2  . PHE B 1 74  ? 13.374  46.348  6.802   0.33  19.115 ? 242 PHE D CE2  1 ? 
ATOM   4828 C CZ   . PHE B 1 74  ? 12.601  45.681  7.737   0.33  19.383 ? 242 PHE D CZ   1 ? 
ATOM   4829 H H    . PHE B 1 74  ? 13.648  50.447  7.688   0.33  22.809 ? 242 PHE D H    1 c 
ATOM   4830 H HA   . PHE B 1 74  ? 13.884  49.788  10.293  0.33  22.029 ? 242 PHE D HA   1 c 
ATOM   4831 H HB2  . PHE B 1 74  ? 15.762  49.151  8.24    0.33  20.965 ? 242 PHE D HB2  1 c 
ATOM   4832 H HB3  . PHE B 1 74  ? 15.806  48.523  9.701   0.33  20.965 ? 242 PHE D HB3  1 c 
ATOM   4833 H HD1  . PHE B 1 74  ? 13.544  47.293  10.389  0.33  19.006 ? 242 PHE D HD1  1 c 
ATOM   4834 H HD2  . PHE B 1 74  ? 14.723  47.84   6.563   0.33  19.688 ? 242 PHE D HD2  1 c 
ATOM   4835 H HE1  . PHE B 1 74  ? 12.141  45.572  9.701   0.33  18.678 ? 242 PHE D HE1  1 c 
ATOM   4836 H HE2  . PHE B 1 74  ? 13.315  46.118  5.889   0.33  19.358 ? 242 PHE D HE2  1 c 
ATOM   4837 H HZ   . PHE B 1 74  ? 12.025  44.986  7.461   0.33  19.048 ? 242 PHE D HZ   1 c 
ATOM   4838 N N    . THR B 1 75  ? 15.653  51.078  11.431  0.33  22.769 ? 243 THR D N    1 ? 
ATOM   4839 C CA   . THR B 1 75  ? 16.49   52.053  12.101  0.33  22.278 ? 243 THR D CA   1 ? 
ATOM   4840 C C    . THR B 1 75  ? 17.922  51.541  12.092  0.33  22.414 ? 243 THR D C    1 ? 
ATOM   4841 O O    . THR B 1 75  ? 18.137  50.352  11.896  0.33  23.473 ? 243 THR D O    1 ? 
ATOM   4842 C CB   . THR B 1 75  ? 16.005  52.261  13.532  0.33  22.195 ? 243 THR D CB   1 ? 
ATOM   4843 O OG1  . THR B 1 75  ? 16.263  51.041  14.216  0.33  22.969 ? 243 THR D OG1  1 ? 
ATOM   4844 C CG2  . THR B 1 75  ? 14.534  52.614  13.603  0.33  22.625 ? 243 THR D CG2  1 ? 
ATOM   4845 H H    . THR B 1 75  ? 15.252  50.424  11.927  0.33  22.518 ? 243 THR D H    1 c 
ATOM   4846 H HA   . THR B 1 75  ? 16.444  52.904  11.615  0.33  22.383 ? 243 THR D HA   1 c 
ATOM   4847 H HB   . THR B 1 75  ? 16.528  52.986  13.952  0.33  22.439 ? 243 THR D HB   1 c 
ATOM   4848 H HG21 . THR B 1 75  ? 14.275  52.742  14.531  0.33  22.497 ? 243 THR D HG21 1 c 
ATOM   4849 H HG22 . THR B 1 75  ? 14.008  51.893  13.217  0.33  22.497 ? 243 THR D HG22 1 c 
ATOM   4850 H HG23 . THR B 1 75  ? 14.372  53.433  13.106  0.33  22.497 ? 243 THR D HG23 1 c 
ATOM   4851 N N    . ALA B 1 76  ? 18.882  52.434  12.355  0.33  21.369 ? 244 ALA D N    1 ? 
ATOM   4852 C CA   . ALA B 1 76  ? 20.276  52.043  12.506  0.33  21.105 ? 244 ALA D CA   1 ? 
ATOM   4853 C C    . ALA B 1 76  ? 20.397  50.945  13.567  0.33  20.469 ? 244 ALA D C    1 ? 
ATOM   4854 O O    . ALA B 1 76  ? 21.172  50.007  13.412  0.33  19.539 ? 244 ALA D O    1 ? 
ATOM   4855 C CB   . ALA B 1 76  ? 21.12   53.247  12.858  0.33  20.932 ? 244 ALA D CB   1 ? 
ATOM   4856 H H    . ALA B 1 76  ? 18.66   53.317  12.444  0.33  21.553 ? 244 ALA D H    1 c 
ATOM   4857 H HA   . ALA B 1 76  ? 20.589  51.67   11.636  0.33  21.007 ? 244 ALA D HA   1 c 
ATOM   4858 H HB1  . ALA B 1 76  ? 21.049  53.913  12.154  0.33  20.983 ? 244 ALA D HB1  1 c 
ATOM   4859 H HB2  . ALA B 1 76  ? 20.808  53.631  13.695  0.33  20.983 ? 244 ALA D HB2  1 c 
ATOM   4860 H HB3  . ALA B 1 76  ? 22.049  52.978  12.954  0.33  20.983 ? 244 ALA D HB3  1 c 
ATOM   4861 N N    . ALA B 1 77  ? 19.628  51.067  14.655  0.33  21.978 ? 245 ALA D N    1 ? 
ATOM   4862 C CA   . ALA B 1 77  ? 19.682  50.084  15.721  0.33  21.554 ? 245 ALA D CA   1 ? 
ATOM   4863 C C    . ALA B 1 77  ? 19.247  48.713  15.197  0.33  21.539 ? 245 ALA D C    1 ? 
ATOM   4864 O O    . ALA B 1 77  ? 19.849  47.71   15.544  0.33  21.783 ? 245 ALA D O    1 ? 
ATOM   4865 C CB   . ALA B 1 77  ? 18.84   50.544  16.891  0.33  22.408 ? 245 ALA D CB   1 ? 
ATOM   4866 H H    . ALA B 1 77  ? 19.058  51.778  14.732  0.33  21.514 ? 245 ALA D H    1 c 
ATOM   4867 H HA   . ALA B 1 77  ? 20.63   50.01   16.02   0.33  21.788 ? 245 ALA D HA   1 c 
ATOM   4868 H HB1  . ALA B 1 77  ? 19.179  51.391  17.225  0.33  22.152 ? 245 ALA D HB1  1 c 
ATOM   4869 H HB2  . ALA B 1 77  ? 17.918  50.657  16.605  0.33  22.152 ? 245 ALA D HB2  1 c 
ATOM   4870 H HB3  . ALA B 1 77  ? 18.877  49.881  17.601  0.33  22.152 ? 245 ALA D HB3  1 c 
ATOM   4871 N N    . GLU B 1 78  ? 18.205  48.655  14.365  0.33  20.528 ? 246 GLU D N    1 ? 
ATOM   4872 C CA   . GLU B 1 78  ? 17.75   47.385  13.814  0.33  20.165 ? 246 GLU D CA   1 ? 
ATOM   4873 C C    . GLU B 1 78  ? 18.8    46.788  12.87   0.33  20.893 ? 246 GLU D C    1 ? 
ATOM   4874 O O    . GLU B 1 78  ? 19.06   45.587  12.884  0.33  21.715 ? 246 GLU D O    1 ? 
ATOM   4875 C CB   . GLU B 1 78  ? 16.415  47.591  13.103  0.33  19.991 ? 246 GLU D CB   1 ? 
ATOM   4876 C CG   . GLU B 1 78  ? 15.235  47.81   14.048  0.33  20.828 ? 246 GLU D CG   1 ? 
ATOM   4877 C CD   . GLU B 1 78  ? 13.922  48.035  13.321  0.33  20.153 ? 246 GLU D CD   1 ? 
ATOM   4878 O OE1  . GLU B 1 78  ? 13.795  49.106  12.694  0.33  19.254 ? 246 GLU D OE1  1 ? 
ATOM   4879 O OE2  . GLU B 1 78  ? 13.041  47.146  13.34   0.33  22.463 ? 246 GLU D OE2  1 ? 
ATOM   4880 H H    . GLU B 1 78  ? 17.766  49.423  14.134  0.33  20.682 ? 246 GLU D H    1 c 
ATOM   4881 H HA   . GLU B 1 78  ? 17.611  46.755  14.567  0.33  20.334 ? 246 GLU D HA   1 c 
ATOM   4882 H HB2  . GLU B 1 78  ? 16.492  48.366  12.509  0.33  20.218 ? 246 GLU D HB2  1 c 
ATOM   4883 H HB3  . GLU B 1 78  ? 16.231  46.806  12.546  0.33  20.218 ? 246 GLU D HB3  1 c 
ATOM   4884 H HG2  . GLU B 1 78  ? 15.141  47.028  14.632  0.33  20.48  ? 246 GLU D HG2  1 c 
ATOM   4885 H HG3  . GLU B 1 78  ? 15.417  48.589  14.616  0.33  20.48  ? 246 GLU D HG3  1 c 
ATOM   4886 N N    . ILE B 1 79  ? 19.414  47.63   12.037  0.33  19.583 ? 247 ILE D N    1 ? 
ATOM   4887 C CA   . ILE B 1 79  ? 20.423  47.152  11.115  0.33  18.351 ? 247 ILE D CA   1 ? 
ATOM   4888 C C    . ILE B 1 79  ? 21.678  46.728  11.878  0.33  18.428 ? 247 ILE D C    1 ? 
ATOM   4889 O O    . ILE B 1 79  ? 22.283  45.707  11.542  0.33  17.322 ? 247 ILE D O    1 ? 
ATOM   4890 C CB   . ILE B 1 79  ? 20.685  48.203  10.018  0.33  17.226 ? 247 ILE D CB   1 ? 
ATOM   4891 C CG1  . ILE B 1 79  ? 19.405  48.465  9.224   0.33  16.681 ? 247 ILE D CG1  1 ? 
ATOM   4892 C CG2  . ILE B 1 79  ? 21.843  47.771  9.128   0.33  16.688 ? 247 ILE D CG2  1 ? 
ATOM   4893 C CD1  . ILE B 1 79  ? 18.766  47.228  8.615   0.33  17.259 ? 247 ILE D CD1  1 ? 
ATOM   4894 H H    . ILE B 1 79  ? 19.199  48.518  12.045  0.33  19.598 ? 247 ILE D H    1 c 
ATOM   4895 H HA   . ILE B 1 79  ? 20.063  46.357  10.676  0.33  18.384 ? 247 ILE D HA   1 c 
ATOM   4896 H HB   . ILE B 1 79  ? 20.938  49.039  10.458  0.33  17.222 ? 247 ILE D HB   1 c 
ATOM   4897 H HG12 . ILE B 1 79  ? 18.753  48.891  9.818   0.33  16.935 ? 247 ILE D HG12 1 c 
ATOM   4898 H HG13 . ILE B 1 79  ? 19.609  49.097  8.505   0.33  16.935 ? 247 ILE D HG13 1 c 
ATOM   4899 H HG21 . ILE B 1 79  ? 21.997  48.444  8.444   0.33  16.845 ? 247 ILE D HG21 1 c 
ATOM   4900 H HG22 . ILE B 1 79  ? 21.63   46.923  8.704   0.33  16.845 ? 247 ILE D HG22 1 c 
ATOM   4901 H HG23 . ILE B 1 79  ? 22.646  47.669  9.666   0.33  16.845 ? 247 ILE D HG23 1 c 
ATOM   4902 H HD11 . ILE B 1 79  ? 19.396  46.803  8.002   0.33  17.086 ? 247 ILE D HD11 1 c 
ATOM   4903 H HD12 . ILE B 1 79  ? 17.961  47.482  8.126   0.33  17.086 ? 247 ILE D HD12 1 c 
ATOM   4904 H HD13 . ILE B 1 79  ? 18.53   46.599  9.323   0.33  17.086 ? 247 ILE D HD13 1 c 
ATOM   4905 N N    . SER B 1 80  ? 22.035  47.47   12.934  0.33  18.769 ? 248 SER D N    1 ? 
ATOM   4906 C CA   . SER B 1 80  ? 23.192  47.128  13.748  0.33  19.886 ? 248 SER D CA   1 ? 
ATOM   4907 C C    . SER B 1 80  ? 23.017  45.734  14.352  0.33  19.293 ? 248 SER D C    1 ? 
ATOM   4908 O O    . SER B 1 80  ? 23.976  44.99   14.474  0.33  19.639 ? 248 SER D O    1 ? 
ATOM   4909 C CB   . SER B 1 80  ? 23.455  48.165  14.826  0.33  20.228 ? 248 SER D CB   1 ? 
ATOM   4910 O OG   . SER B 1 80  ? 23.965  49.36   14.25   0.33  21.747 ? 248 SER D OG   1 ? 
ATOM   4911 H H    . SER B 1 80  ? 21.543  48.209  13.152  0.33  18.932 ? 248 SER D H    1 c 
ATOM   4912 H HA   . SER B 1 80  ? 23.982  47.101  13.151  0.33  19.616 ? 248 SER D HA   1 c 
ATOM   4913 H HB2  . SER B 1 80  ? 22.624  48.359  15.299  0.33  20.501 ? 248 SER D HB2  1 c 
ATOM   4914 H HB3  . SER B 1 80  ? 24.099  47.81   15.467  0.33  20.501 ? 248 SER D HB3  1 c 
ATOM   4915 N N    . ALA B 1 81  ? 21.785  45.392  14.722  0.33  21.061 ? 249 ALA D N    1 ? 
ATOM   4916 C CA   . ALA B 1 81  ? 21.491  44.106  15.327  0.33  22.046 ? 249 ALA D CA   1 ? 
ATOM   4917 C C    . ALA B 1 81  ? 21.817  42.972  14.352  0.33  22.257 ? 249 ALA D C    1 ? 
ATOM   4918 O O    . ALA B 1 81  ? 22.315  41.938  14.78   0.33  21.717 ? 249 ALA D O    1 ? 
ATOM   4919 C CB   . ALA B 1 81  ? 20.057  44.076  15.804  0.33  20.678 ? 249 ALA D CB   1 ? 
ATOM   4920 H H    . ALA B 1 81  ? 21.101  45.984  14.591  0.33  20.839 ? 249 ALA D H    1 c 
ATOM   4921 H HA   . ALA B 1 81  ? 22.089  44.003  16.119  0.33  21.632 ? 249 ALA D HA   1 c 
ATOM   4922 H HB1  . ALA B 1 81  ? 19.917  44.777  16.463  0.33  21.075 ? 249 ALA D HB1  1 c 
ATOM   4923 H HB2  . ALA B 1 81  ? 19.459  44.22   15.051  0.33  21.075 ? 249 ALA D HB2  1 c 
ATOM   4924 H HB3  . ALA B 1 81  ? 19.864  43.213  16.207  0.33  21.075 ? 249 ALA D HB3  1 c 
ATOM   4925 N N    . LEU B 1 82  ? 21.609  43.158  13.037  0.33  21.898 ? 250 LEU D N    1 ? 
ATOM   4926 C CA   . LEU B 1 82  ? 22.019  42.147  12.066  0.33  21.616 ? 250 LEU D CA   1 ? 
ATOM   4927 C C    . LEU B 1 82  ? 23.535  42.105  11.951  0.33  21.981 ? 250 LEU D C    1 ? 
ATOM   4928 O O    . LEU B 1 82  ? 24.12   41.039  11.851  0.33  23.865 ? 250 LEU D O    1 ? 
ATOM   4929 C CB   . LEU B 1 82  ? 21.439  42.398  10.68   0.33  22.674 ? 250 LEU D CB   1 ? 
ATOM   4930 C CG   . LEU B 1 82  ? 20.052  41.826  10.422  0.33  23.448 ? 250 LEU D CG   1 ? 
ATOM   4931 C CD1  . LEU B 1 82  ? 19.061  42.478  11.381  0.33  25.441 ? 250 LEU D CD1  1 ? 
ATOM   4932 C CD2  . LEU B 1 82  ? 19.731  42.044  8.948   0.33  22.586 ? 250 LEU D CD2  1 ? 
ATOM   4933 H H    . LEU B 1 82  ? 21.207  43.924  12.742  0.33  21.919 ? 250 LEU D H    1 c 
ATOM   4934 H HA   . LEU B 1 82  ? 21.706  41.264  12.391  0.33  21.928 ? 250 LEU D HA   1 c 
ATOM   4935 H HB2  . LEU B 1 82  ? 21.406  43.371  10.533  0.33  22.6   ? 250 LEU D HB2  1 c 
ATOM   4936 H HB3  . LEU B 1 82  ? 22.059  42.018  10.015  0.33  22.6   ? 250 LEU D HB3  1 c 
ATOM   4937 H HG   . LEU B 1 82  ? 20.074  40.851  10.602  0.33  23.493 ? 250 LEU D HG   1 c 
ATOM   4938 H HD11 . LEU B 1 82  ? 19.327  42.295  12.297  0.33  24.837 ? 250 LEU D HD11 1 c 
ATOM   4939 H HD12 . LEU B 1 82  ? 18.172  42.117  11.224  0.33  24.837 ? 250 LEU D HD12 1 c 
ATOM   4940 H HD13 . LEU B 1 82  ? 19.05   43.439  11.233  0.33  24.837 ? 250 LEU D HD13 1 c 
ATOM   4941 H HD21 . LEU B 1 82  ? 20.398  41.596  8.401   0.33  22.836 ? 250 LEU D HD21 1 c 
ATOM   4942 H HD22 . LEU B 1 82  ? 19.738  42.996  8.751   0.33  22.837 ? 250 LEU D HD22 1 c 
ATOM   4943 H HD23 . LEU B 1 82  ? 18.852  41.679  8.75    0.33  22.836 ? 250 LEU D HD23 1 c 
ATOM   4944 N N    . LYS B 1 83  ? 24.167  43.275  11.89   0.33  22.532 ? 251 LYS D N    1 ? 
ATOM   4945 C CA   . LYS B 1 83  ? 25.606  43.324  11.694  0.33  23.897 ? 251 LYS D CA   1 ? 
ATOM   4946 C C    . LYS B 1 83  ? 26.318  42.69   12.891  0.33  23.662 ? 251 LYS D C    1 ? 
ATOM   4947 O O    . LYS B 1 83  ? 27.377  42.097  12.73   0.33  22.782 ? 251 LYS D O    1 ? 
ATOM   4948 C CB   . LYS B 1 83  ? 26.054  44.759  11.407  0.33  22.072 ? 251 LYS D CB   1 ? 
ATOM   4949 C CG   . LYS B 1 83  ? 25.467  45.353  10.129  0.33  22.658 ? 251 LYS D CG   1 ? 
ATOM   4950 C CD   . LYS B 1 83  ? 26.093  46.67   9.674   0.33  23.053 ? 251 LYS D CD   1 ? 
ATOM   4951 C CE   . LYS B 1 83  ? 25.91   47.761  10.678  0.33  25.371 ? 251 LYS D CE   1 ? 
ATOM   4952 N NZ   . LYS B 1 83  ? 26.46   49.015  10.146  0.33  24.838 ? 251 LYS D NZ   1 ? 
ATOM   4953 H H    . LYS B 1 83  ? 23.699  44.056  11.971  0.33  22.697 ? 251 LYS D H    1 c 
ATOM   4954 H HA   . LYS B 1 83  ? 25.818  42.78   10.893  0.33  23.24  ? 251 LYS D HA   1 c 
ATOM   4955 H HB2  . LYS B 1 83  ? 25.796  45.329  12.163  0.33  22.608 ? 251 LYS D HB2  1 c 
ATOM   4956 H HB3  . LYS B 1 83  ? 27.032  44.778  11.339  0.33  22.608 ? 251 LYS D HB3  1 c 
ATOM   4957 H HG2  . LYS B 1 83  ? 25.566  44.693  9.409   0.33  22.611 ? 251 LYS D HG2  1 c 
ATOM   4958 H HG3  . LYS B 1 83  ? 24.505  45.494  10.269  0.33  22.611 ? 251 LYS D HG3  1 c 
ATOM   4959 H HD2  . LYS B 1 83  ? 27.054  46.533  9.521   0.33  23.48  ? 251 LYS D HD2  1 c 
ATOM   4960 H HD3  . LYS B 1 83  ? 25.685  46.944  8.824   0.33  23.48  ? 251 LYS D HD3  1 c 
ATOM   4961 H HE2  . LYS B 1 83  ? 24.962  47.881  10.871  0.33  24.698 ? 251 LYS D HE2  1 c 
ATOM   4962 H HE3  . LYS B 1 83  ? 26.369  47.533  11.506  0.33  24.698 ? 251 LYS D HE3  1 c 
ATOM   4963 H HZ1  . LYS B 1 83  ? 26.026  49.24   9.383   0.33  25.001 ? 251 LYS D HZ1  1 c 
ATOM   4964 H HZ2  . LYS B 1 83  ? 27.342  48.911  9.967   0.33  25.001 ? 251 LYS D HZ2  1 c 
ATOM   4965 H HZ3  . LYS B 1 83  ? 26.356  49.678  10.754  0.33  25.001 ? 251 LYS D HZ3  1 c 
ATOM   4966 N N    . ALA B 1 84  ? 25.733  42.811  14.086  0.33  25.604 ? 252 ALA D N    1 ? 
ATOM   4967 C CA   . ALA B 1 84  ? 26.361  42.315  15.302  0.33  25.925 ? 252 ALA D CA   1 ? 
ATOM   4968 C C    . ALA B 1 84  ? 26.4    40.79   15.293  0.33  28.17  ? 252 ALA D C    1 ? 
ATOM   4969 O O    . ALA B 1 84  ? 27.249  40.19   15.947  0.33  28.924 ? 252 ALA D O    1 ? 
ATOM   4970 C CB   . ALA B 1 84  ? 25.618  42.827  16.517  0.33  26.165 ? 252 ALA D CB   1 ? 
ATOM   4971 H H    . ALA B 1 84  ? 24.916  43.216  14.145  0.33  25.198 ? 252 ALA D H    1 c 
ATOM   4972 H HA   . ALA B 1 84  ? 27.299  42.651  15.328  0.33  26.303 ? 252 ALA D HA   1 c 
ATOM   4973 H HB1  . ALA B 1 84  ? 25.638  43.799  16.526  0.33  26.094 ? 252 ALA D HB1  1 c 
ATOM   4974 H HB2  . ALA B 1 84  ? 24.695  42.525  16.487  0.33  26.094 ? 252 ALA D HB2  1 c 
ATOM   4975 H HB3  . ALA B 1 84  ? 26.04   42.489  17.324  0.33  26.094 ? 252 ALA D HB3  1 c 
ATOM   4976 N N    . ARG B 1 85  ? 25.466  40.187  14.552  0.33  27.878 ? 253 ARG D N    1 ? 
ATOM   4977 C CA   . ARG B 1 85  ? 25.414  38.748  14.355  0.33  27.719 ? 253 ARG D CA   1 ? 
ATOM   4978 C C    . ARG B 1 85  ? 26.336  38.344  13.201  0.33  27.938 ? 253 ARG D C    1 ? 
ATOM   4979 O O    . ARG B 1 85  ? 26.365  37.181  12.812  0.33  32.435 ? 253 ARG D O    1 ? 
ATOM   4980 C CB   . ARG B 1 85  ? 23.981  38.292  14.063  0.33  27.578 ? 253 ARG D CB   1 ? 
ATOM   4981 C CG   . ARG B 1 85  ? 22.947  38.553  15.149  0.33  27.506 ? 253 ARG D CG   1 ? 
ATOM   4982 H H    . ARG B 1 85  ? 24.828  40.702  14.15   0.33  27.911 ? 253 ARG D H    1 c 
ATOM   4983 H HA   . ARG B 1 85  ? 25.731  38.307  15.184  0.33  27.764 ? 253 ARG D HA   1 c 
ATOM   4984 H HB2  . ARG B 1 85  ? 23.682  38.736  13.241  0.33  27.594 ? 253 ARG D HB2  1 c 
ATOM   4985 H HB3  . ARG B 1 85  ? 23.999  37.328  13.883  0.33  27.594 ? 253 ARG D HB3  1 c 
ATOM   4986 N N    . GLY B 1 86  ? 27.075  39.311  12.643  0.33  26.375 ? 254 GLY D N    1 ? 
ATOM   4987 C CA   . GLY B 1 86  ? 28.125  39.016  11.681  0.33  25.422 ? 254 GLY D CA   1 ? 
ATOM   4988 C C    . GLY B 1 86  ? 27.717  39.26   10.227  0.33  21.787 ? 254 GLY D C    1 ? 
ATOM   4989 O O    . GLY B 1 86  ? 28.562  39.146  9.347   0.33  22.143 ? 254 GLY D O    1 ? 
ATOM   4990 H H    . GLY B 1 86  ? 26.918  40.182  12.871  0.33  26.519 ? 254 GLY D H    1 c 
ATOM   4991 H HA2  . GLY B 1 86  ? 28.911  39.573  11.893  0.33  24.779 ? 254 GLY D HA2  1 c 
ATOM   4992 H HA3  . GLY B 1 86  ? 28.392  38.073  11.786  0.33  24.779 ? 254 GLY D HA3  1 c 
ATOM   4993 N N    . LYS B 1 87  ? 26.448  39.601  9.978   0.33  18.599 ? 255 LYS D N    1 ? 
ATOM   4994 C CA   . LYS B 1 87  ? 25.925  39.677  8.624   0.33  17.933 ? 255 LYS D CA   1 ? 
ATOM   4995 C C    . LYS B 1 87  ? 26.279  41.007  7.972   0.33  15.469 ? 255 LYS D C    1 ? 
ATOM   4996 O O    . LYS B 1 87  ? 26.21   42.054  8.605   0.33  16.272 ? 255 LYS D O    1 ? 
ATOM   4997 C CB   . LYS B 1 87  ? 24.404  39.555  8.55    0.33  18.024 ? 255 LYS D CB   1 ? 
ATOM   4998 C CG   . LYS B 1 87  ? 23.886  38.257  9.134   0.33  20.369 ? 255 LYS D CG   1 ? 
ATOM   4999 C CD   . LYS B 1 87  ? 22.377  38.17   9.086   0.33  21.536 ? 255 LYS D CD   1 ? 
ATOM   5000 C CE   . LYS B 1 87  ? 21.885  36.789  9.349   0.33  22.401 ? 255 LYS D CE   1 ? 
ATOM   5001 N NZ   . LYS B 1 87  ? 22.557  36.207  10.508  0.33  22.565 ? 255 LYS D NZ   1 ? 
ATOM   5002 H H    . LYS B 1 87  ? 25.891  39.792  10.677  0.33  19.157 ? 255 LYS D H    1 c 
ATOM   5003 H HA   . LYS B 1 87  ? 26.332  38.945  8.092   0.33  17.594 ? 255 LYS D HA   1 c 
ATOM   5004 H HB2  . LYS B 1 87  ? 23.998  40.304  9.037   0.33  18.517 ? 255 LYS D HB2  1 c 
ATOM   5005 H HB3  . LYS B 1 87  ? 24.122  39.615  7.613   0.33  18.517 ? 255 LYS D HB3  1 c 
ATOM   5006 H HG2  . LYS B 1 87  ? 24.271  37.507  8.63    0.33  20.059 ? 255 LYS D HG2  1 c 
ATOM   5007 H HG3  . LYS B 1 87  ? 24.186  38.187  10.066  0.33  20.059 ? 255 LYS D HG3  1 c 
ATOM   5008 H HD2  . LYS B 1 87  ? 21.998  38.779  9.756   0.33  21.46  ? 255 LYS D HD2  1 c 
ATOM   5009 H HD3  . LYS B 1 87  ? 22.066  38.458  8.2     0.33  21.46  ? 255 LYS D HD3  1 c 
ATOM   5010 H HE2  . LYS B 1 87  ? 20.926  36.809  9.513   0.33  22.238 ? 255 LYS D HE2  1 c 
ATOM   5011 H HE3  . LYS B 1 87  ? 22.051  36.228  8.57    0.33  22.238 ? 255 LYS D HE3  1 c 
ATOM   5012 H HZ1  . LYS B 1 87  ? 22.38   36.702  11.245  0.33  22.515 ? 255 LYS D HZ1  1 c 
ATOM   5013 H HZ2  . LYS B 1 87  ? 23.452  36.191  10.368  0.33  22.515 ? 255 LYS D HZ2  1 c 
ATOM   5014 H HZ3  . LYS B 1 87  ? 22.261  35.36   10.64   0.33  22.515 ? 255 LYS D HZ3  1 c 
ATOM   5015 N N    . GLN B 1 88  ? 26.656  40.931  6.696   0.33  14.383 ? 256 GLN D N    1 ? 
ATOM   5016 C CA   . GLN B 1 88  ? 26.61   42.079  5.8     0.33  14.589 ? 256 GLN D CA   1 ? 
ATOM   5017 C C    . GLN B 1 88  ? 25.149  42.333  5.454   0.33  14.15  ? 256 GLN D C    1 ? 
ATOM   5018 O O    . GLN B 1 88  ? 24.387  41.38   5.363   0.33  13.61  ? 256 GLN D O    1 ? 
ATOM   5019 C CB   . GLN B 1 88  ? 27.353  41.773  4.505   0.33  15.118 ? 256 GLN D CB   1 ? 
ATOM   5020 C CG   . GLN B 1 88  ? 28.851  41.559  4.666   0.33  16.166 ? 256 GLN D CG   1 ? 
ATOM   5021 C CD   . GLN B 1 88  ? 29.619  42.848  4.838   0.33  16.72  ? 256 GLN D CD   1 ? 
ATOM   5022 O OE1  . GLN B 1 88  ? 29.31   43.853  4.187   0.33  17.01  ? 256 GLN D OE1  1 ? 
ATOM   5023 N NE2  . GLN B 1 88  ? 30.566  42.842  5.772   0.33  16.326 ? 256 GLN D NE2  1 ? 
ATOM   5024 H H    . GLN B 1 88  ? 26.954  40.131  6.369   0.33  14.682 ? 256 GLN D H    1 c 
ATOM   5025 H HA   . GLN B 1 88  ? 26.993  42.87   6.259   0.33  14.561 ? 256 GLN D HA   1 c 
ATOM   5026 H HB2  . GLN B 1 88  ? 26.961  40.968  4.106   0.33  15.227 ? 256 GLN D HB2  1 c 
ATOM   5027 H HB3  . GLN B 1 88  ? 27.205  42.513  3.88    0.33  15.227 ? 256 GLN D HB3  1 c 
ATOM   5028 H HG2  . GLN B 1 88  ? 29.014  40.989  5.447   0.33  16.046 ? 256 GLN D HG2  1 c 
ATOM   5029 H HG3  . GLN B 1 88  ? 29.197  41.09   3.876   0.33  16.046 ? 256 GLN D HG3  1 c 
ATOM   5030 H HE21 . GLN B 1 88  ? 31.046  43.573  5.92    0.33  16.447 ? 256 GLN D HE21 1 c 
ATOM   5031 H HE22 . GLN B 1 88  ? 30.716  42.107  6.245   0.33  16.447 ? 256 GLN D HE22 1 c 
ATOM   5032 N N    . VAL B 1 89  ? 24.75   43.596  5.279   0.33  13.979 ? 257 VAL D N    1 ? 
ATOM   5033 C CA   . VAL B 1 89  ? 23.352  43.881  5.004   0.33  14.092 ? 257 VAL D CA   1 ? 
ATOM   5034 C C    . VAL B 1 89  ? 23.283  44.851  3.828   0.33  13.751 ? 257 VAL D C    1 ? 
ATOM   5035 O O    . VAL B 1 89  ? 23.867  45.93   3.904   0.33  13.834 ? 257 VAL D O    1 ? 
ATOM   5036 C CB   . VAL B 1 89  ? 22.591  44.463  6.212   0.33  14.648 ? 257 VAL D CB   1 ? 
ATOM   5037 C CG1  . VAL B 1 89  ? 21.091  44.494  5.943   0.33  14.746 ? 257 VAL D CG1  1 ? 
ATOM   5038 C CG2  . VAL B 1 89  ? 22.892  43.719  7.509   0.33  14.728 ? 257 VAL D CG2  1 ? 
ATOM   5039 H H    . VAL B 1 89  ? 25.349  44.284  5.331   0.33  14.045 ? 257 VAL D H    1 c 
ATOM   5040 H HA   . VAL B 1 89  ? 22.918  43.046  4.74    0.33  14.105 ? 257 VAL D HA   1 c 
ATOM   5041 H HB   . VAL B 1 89  ? 22.894  45.395  6.324   0.33  14.576 ? 257 VAL D HB   1 c 
ATOM   5042 H HG11 . VAL B 1 89  ? 20.772  43.591  5.776   0.33  14.717 ? 257 VAL D HG11 1 c 
ATOM   5043 H HG12 . VAL B 1 89  ? 20.912  45.049  5.166   0.33  14.717 ? 257 VAL D HG12 1 c 
ATOM   5044 H HG13 . VAL B 1 89  ? 20.63   44.862  6.716   0.33  14.717 ? 257 VAL D HG13 1 c 
ATOM   5045 H HG21 . VAL B 1 89  ? 22.401  44.129  8.24    0.33  14.704 ? 257 VAL D HG21 1 c 
ATOM   5046 H HG22 . VAL B 1 89  ? 23.845  43.763  7.695   0.33  14.704 ? 257 VAL D HG22 1 c 
ATOM   5047 H HG23 . VAL B 1 89  ? 22.623  42.789  7.42    0.33  14.704 ? 257 VAL D HG23 1 c 
ATOM   5048 N N    . LEU B 1 90  ? 22.544  44.474  2.767   0.33  12.46  ? 258 LEU D N    1 ? 
ATOM   5049 C CA   . LEU B 1 90  ? 22.374  45.322  1.593   0.33  11.976 ? 258 LEU D CA   1 ? 
ATOM   5050 C C    . LEU B 1 90  ? 20.943  45.829  1.56    0.33  12.606 ? 258 LEU D C    1 ? 
ATOM   5051 O O    . LEU B 1 90  ? 20.039  45.083  1.894   0.33  12.485 ? 258 LEU D O    1 ? 
ATOM   5052 C CB   . LEU B 1 90  ? 22.679  44.599  0.282   0.33  11.59  ? 258 LEU D CB   1 ? 
ATOM   5053 C CG   . LEU B 1 90  ? 24.09   44.03   0.148   0.33  11.651 ? 258 LEU D CG   1 ? 
ATOM   5054 C CD1  . LEU B 1 90  ? 24.262  43.265  -1.154  0.33  11.576 ? 258 LEU D CD1  1 ? 
ATOM   5055 C CD2  . LEU B 1 90  ? 25.087  45.151  0.233   0.33  11.357 ? 258 LEU D CD2  1 ? 
ATOM   5056 H H    . LEU B 1 90  ? 22.133  43.658  2.781   0.33  12.644 ? 258 LEU D H    1 c 
ATOM   5057 H HA   . LEU B 1 90  ? 22.982  46.1    1.683   0.33  12.111 ? 258 LEU D HA   1 c 
ATOM   5058 H HB2  . LEU B 1 90  ? 22.036  43.86   0.183   0.33  11.691 ? 258 LEU D HB2  1 c 
ATOM   5059 H HB3  . LEU B 1 90  ? 22.527  45.229  -0.459  0.33  11.691 ? 258 LEU D HB3  1 c 
ATOM   5060 H HG   . LEU B 1 90  ? 24.251  43.407  0.903   0.33  11.57  ? 258 LEU D HG   1 c 
ATOM   5061 H HD11 . LEU B 1 90  ? 23.631  42.526  -1.183  0.33  11.598 ? 258 LEU D HD11 1 c 
ATOM   5062 H HD12 . LEU B 1 90  ? 25.168  42.918  -1.211  0.33  11.598 ? 258 LEU D HD12 1 c 
ATOM   5063 H HD13 . LEU B 1 90  ? 24.097  43.86   -1.905  0.33  11.598 ? 258 LEU D HD13 1 c 
ATOM   5064 H HD21 . LEU B 1 90  ? 25      45.599  1.092   0.33  11.444 ? 258 LEU D HD21 1 c 
ATOM   5065 H HD22 . LEU B 1 90  ? 24.921  45.789  -0.481  0.33  11.444 ? 258 LEU D HD22 1 c 
ATOM   5066 H HD23 . LEU B 1 90  ? 25.986  44.794  0.145   0.33  11.444 ? 258 LEU D HD23 1 c 
ATOM   5067 N N    . ALA B 1 91  ? 20.773  47.094  1.173   0.33  12.889 ? 259 ALA D N    1 ? 
ATOM   5068 C CA   . ALA B 1 91  ? 19.467  47.692  0.988   0.33  13.414 ? 259 ALA D CA   1 ? 
ATOM   5069 C C    . ALA B 1 91  ? 19.041  47.535  -0.47   0.33  13.13  ? 259 ALA D C    1 ? 
ATOM   5070 O O    . ALA B 1 91  ? 19.671  48.033  -1.398  0.33  11.839 ? 259 ALA D O    1 ? 
ATOM   5071 C CB   . ALA B 1 91  ? 19.463  49.144  1.447   0.33  14.118 ? 259 ALA D CB   1 ? 
ATOM   5072 H H    . ALA B 1 91  ? 21.512  47.608  1.017   0.33  12.938 ? 259 ALA D H    1 c 
ATOM   5073 H HA   . ALA B 1 91  ? 18.819  47.182  1.549   0.33  13.382 ? 259 ALA D HA   1 c 
ATOM   5074 H HB1  . ALA B 1 91  ? 19.688  49.19   2.391   0.33  13.907 ? 259 ALA D HB1  1 c 
ATOM   5075 H HB2  . ALA B 1 91  ? 20.118  49.65   0.937   0.33  13.907 ? 259 ALA D HB2  1 c 
ATOM   5076 H HB3  . ALA B 1 91  ? 18.582  49.529  1.308   0.33  13.907 ? 259 ALA D HB3  1 c 
ATOM   5077 N N    . TYR B 1 92  ? 17.956  46.794  -0.646  0.33  12.933 ? 260 TYR D N    1 ? 
ATOM   5078 C CA   . TYR B 1 92  ? 17.273  46.672  -1.914  0.33  12.888 ? 260 TYR D CA   1 ? 
ATOM   5079 C C    . TYR B 1 92  ? 16.498  47.95   -2.204  0.33  12.441 ? 260 TYR D C    1 ? 
ATOM   5080 O O    . TYR B 1 92  ? 15.76   48.45   -1.354  0.33  11.26  ? 260 TYR D O    1 ? 
ATOM   5081 C CB   . TYR B 1 92  ? 16.31   45.493  -1.827  0.33  12.988 ? 260 TYR D CB   1 ? 
ATOM   5082 C CG   . TYR B 1 92  ? 15.372  45.419  -3.018  0.33  12.91  ? 260 TYR D CG   1 ? 
ATOM   5083 C CD1  . TYR B 1 92  ? 14.232  46.215  -3.084  0.33  13.074 ? 260 TYR D CD1  1 ? 
ATOM   5084 C CD2  . TYR B 1 92  ? 15.64   44.574  -4.083  0.33  12.604 ? 260 TYR D CD2  1 ? 
ATOM   5085 C CE1  . TYR B 1 92  ? 13.375  46.147  -4.171  0.33  13.344 ? 260 TYR D CE1  1 ? 
ATOM   5086 C CE2  . TYR B 1 92  ? 14.806  44.519  -5.183  0.33  12.508 ? 260 TYR D CE2  1 ? 
ATOM   5087 C CZ   . TYR B 1 92  ? 13.667  45.295  -5.224  0.33  12.948 ? 260 TYR D CZ   1 ? 
ATOM   5088 O OH   . TYR B 1 92  ? 12.864  45.184  -6.308  0.33  13.091 ? 260 TYR D OH   1 ? 
ATOM   5089 H H    . TYR B 1 92  ? 17.621  46.336  0.071   0.33  12.969 ? 260 TYR D H    1 c 
ATOM   5090 H HA   . TYR B 1 92  ? 17.937  46.51   -2.635  0.33  12.833 ? 260 TYR D HA   1 c 
ATOM   5091 H HB2  . TYR B 1 92  ? 16.833  44.662  -1.777  0.33  12.948 ? 260 TYR D HB2  1 c 
ATOM   5092 H HB3  . TYR B 1 92  ? 15.78   45.577  -1.004  0.33  12.948 ? 260 TYR D HB3  1 c 
ATOM   5093 H HD1  . TYR B 1 92  ? 14.026  46.793  -2.367  0.33  13.092 ? 260 TYR D HD1  1 c 
ATOM   5094 H HD2  . TYR B 1 92  ? 16.417  44.038  -4.065  0.33  12.662 ? 260 TYR D HD2  1 c 
ATOM   5095 H HE1  . TYR B 1 92  ? 12.601  46.684  -4.199  0.33  13.179 ? 260 TYR D HE1  1 c 
ATOM   5096 H HE2  . TYR B 1 92  ? 14.997  43.928  -5.891  0.33  12.643 ? 260 TYR D HE2  1 c 
ATOM   5097 N N    . PHE B 1 93  ? 16.702  48.471  -3.412  0.33  12.798 ? 261 PHE D N    1 ? 
ATOM   5098 C CA   . PHE B 1 93  ? 15.772  49.416  -4.008  0.33  13.223 ? 261 PHE D CA   1 ? 
ATOM   5099 C C    . PHE B 1 93  ? 15.916  49.384  -5.528  0.33  13.891 ? 261 PHE D C    1 ? 
ATOM   5100 O O    . PHE B 1 93  ? 16.948  49      -6.068  0.33  12.311 ? 261 PHE D O    1 ? 
ATOM   5101 C CB   . PHE B 1 93  ? 15.921  50.833  -3.448  0.33  13.964 ? 261 PHE D CB   1 ? 
ATOM   5102 C CG   . PHE B 1 93  ? 17.304  51.465  -3.51   0.33  13.309 ? 261 PHE D CG   1 ? 
ATOM   5103 C CD1  . PHE B 1 93  ? 17.708  52.187  -4.625  0.33  14.197 ? 261 PHE D CD1  1 ? 
ATOM   5104 C CD2  . PHE B 1 93  ? 18.163  51.393  -2.416  0.33  13.785 ? 261 PHE D CD2  1 ? 
ATOM   5105 C CE1  . PHE B 1 93  ? 18.964  52.785  -4.651  0.33  13.884 ? 261 PHE D CE1  1 ? 
ATOM   5106 C CE2  . PHE B 1 93  ? 19.398  52.006  -2.44   0.33  13.886 ? 261 PHE D CE2  1 ? 
ATOM   5107 C CZ   . PHE B 1 93  ? 19.795  52.708  -3.562  0.33  14.374 ? 261 PHE D CZ   1 ? 
ATOM   5108 H H    . PHE B 1 93  ? 17.447  48.23   -3.883  0.33  12.806 ? 261 PHE D H    1 c 
ATOM   5109 H HA   . PHE B 1 93  ? 14.854  49.105  -3.788  0.33  13.392 ? 261 PHE D HA   1 c 
ATOM   5110 H HB2  . PHE B 1 93  ? 15.293  51.416  -3.931  0.33  13.641 ? 261 PHE D HB2  1 c 
ATOM   5111 H HB3  . PHE B 1 93  ? 15.63   50.819  -2.509  0.33  13.641 ? 261 PHE D HB3  1 c 
ATOM   5112 H HD1  . PHE B 1 93  ? 17.138  52.254  -5.374  0.33  13.917 ? 261 PHE D HD1  1 c 
ATOM   5113 H HD2  . PHE B 1 93  ? 17.889  50.927  -1.642  0.33  13.708 ? 261 PHE D HD2  1 c 
ATOM   5114 H HE1  . PHE B 1 93  ? 19.237  53.265  -5.416  0.33  14.063 ? 261 PHE D HE1  1 c 
ATOM   5115 H HE2  . PHE B 1 93  ? 19.975  51.936  -1.695  0.33  13.971 ? 261 PHE D HE2  1 c 
ATOM   5116 H HZ   . PHE B 1 93  ? 20.649  53.109  -3.59   0.33  14.136 ? 261 PHE D HZ   1 c 
ATOM   5117 N N    . GLU B 1 94  ? 14.845  49.794  -6.21   0.33  14.999 ? 262 GLU D N    1 ? 
ATOM   5118 C CA   . GLU B 1 94  ? 14.804  49.892  -7.657  0.33  16.401 ? 262 GLU D CA   1 ? 
ATOM   5119 C C    . GLU B 1 94  ? 15.413  51.215  -8.106  0.33  15.95  ? 262 GLU D C    1 ? 
ATOM   5120 O O    . GLU B 1 94  ? 15.294  52.214  -7.407  0.33  16.301 ? 262 GLU D O    1 ? 
ATOM   5121 C CB   . GLU B 1 94  ? 13.366  49.851  -8.169  0.33  17.133 ? 262 GLU D CB   1 ? 
ATOM   5122 C CG   . GLU B 1 94  ? 12.679  48.521  -7.88   0.33  19.292 ? 262 GLU D CG   1 ? 
ATOM   5123 C CD   . GLU B 1 94  ? 11.3    48.366  -8.504  0.33  21.202 ? 262 GLU D CD   1 ? 
ATOM   5124 O OE1  . GLU B 1 94  ? 10.888  47.2    -8.731  0.33  20.412 ? 262 GLU D OE1  1 ? 
ATOM   5125 O OE2  . GLU B 1 94  ? 10.625  49.396  -8.748  0.33  24.201 ? 262 GLU D OE2  1 ? 
ATOM   5126 H H    . GLU B 1 94  ? 14.096  50.026  -5.741  0.33  15.03  ? 262 GLU D H    1 c 
ATOM   5127 H HA   . GLU B 1 94  ? 15.325  49.142  -8.044  0.33  16.162 ? 262 GLU D HA   1 c 
ATOM   5128 H HB2  . GLU B 1 94  ? 12.858  50.575  -7.748  0.33  17.427 ? 262 GLU D HB2  1 c 
ATOM   5129 H HB3  . GLU B 1 94  ? 13.369  50.01   -9.136  0.33  17.427 ? 262 GLU D HB3  1 c 
ATOM   5130 H HG2  . GLU B 1 94  ? 13.249  47.792  -8.206  0.33  19.189 ? 262 GLU D HG2  1 c 
ATOM   5131 H HG3  . GLU B 1 94  ? 12.592  48.413  -6.909  0.33  19.189 ? 262 GLU D HG3  1 c 
ATOM   5132 N N    . ILE B 1 95  ? 16.1    51.183  -9.244  0.33  16.005 ? 263 ILE D N    1 ? 
ATOM   5133 C CA   . ILE B 1 95  ? 16.625  52.401  -9.84   0.33  15.954 ? 263 ILE D CA   1 ? 
ATOM   5134 C C    . ILE B 1 95  ? 16.053  52.596  -11.242 0.33  16.347 ? 263 ILE D C    1 ? 
ATOM   5135 O O    . ILE B 1 95  ? 16.304  53.624  -11.863 0.33  16.465 ? 263 ILE D O    1 ? 
ATOM   5136 C CB   . ILE B 1 95  ? 18.164  52.398  -9.852  0.33  14.877 ? 263 ILE D CB   1 ? 
ATOM   5137 C CG1  . ILE B 1 95  ? 18.737  51.3    -10.746 0.33  15.394 ? 263 ILE D CG1  1 ? 
ATOM   5138 C CG2  . ILE B 1 95  ? 18.695  52.307  -8.424  0.33  14.469 ? 263 ILE D CG2  1 ? 
ATOM   5139 C CD1  . ILE B 1 95  ? 20.234  51.394  -10.981 0.33  16.108 ? 263 ILE D CD1  1 ? 
ATOM   5140 H H    . ILE B 1 95  ? 16.247  50.384  -9.662  0.33  15.98  ? 263 ILE D H    1 c 
ATOM   5141 H HA   . ILE B 1 95  ? 16.332  53.152  -9.288  0.33  15.832 ? 263 ILE D HA   1 c 
ATOM   5142 H HB   . ILE B 1 95  ? 18.455  53.256  -10.221 0.33  15.089 ? 263 ILE D HB   1 c 
ATOM   5143 H HG12 . ILE B 1 95  ? 18.539  50.432  -10.339 0.33  15.434 ? 263 ILE D HG12 1 c 
ATOM   5144 H HG13 . ILE B 1 95  ? 18.282  51.334  -11.612 0.33  15.434 ? 263 ILE D HG13 1 c 
ATOM   5145 H HG21 . ILE B 1 95  ? 19.667  52.317  -8.437  0.33  14.588 ? 263 ILE D HG21 1 c 
ATOM   5146 H HG22 . ILE B 1 95  ? 18.386  51.482  -8.014  0.33  14.588 ? 263 ILE D HG22 1 c 
ATOM   5147 H HG23 . ILE B 1 95  ? 18.372  53.064  -7.908  0.33  14.588 ? 263 ILE D HG23 1 c 
ATOM   5148 H HD11 . ILE B 1 95  ? 20.448  52.256  -11.385 0.33  15.894 ? 263 ILE D HD11 1 c 
ATOM   5149 H HD12 . ILE B 1 95  ? 20.516  50.677  -11.58  0.33  15.894 ? 263 ILE D HD12 1 c 
ATOM   5150 H HD13 . ILE B 1 95  ? 20.704  51.31   -10.13  0.33  15.894 ? 263 ILE D HD13 1 c 
ATOM   5151 N N    . GLY B 1 96  ? 15.267  51.629  -11.731 0.33  16.225 ? 264 GLY D N    1 ? 
ATOM   5152 C CA   . GLY B 1 96  ? 14.786  51.668  -13.104 0.33  15.893 ? 264 GLY D CA   1 ? 
ATOM   5153 C C    . GLY B 1 96  ? 13.266  51.666  -13.215 0.33  16.054 ? 264 GLY D C    1 ? 
ATOM   5154 O O    . GLY B 1 96  ? 12.723  51.6    -14.311 0.33  16.622 ? 264 GLY D O    1 ? 
ATOM   5155 H H    . GLY B 1 96  ? 15.026  50.929  -11.196 0.33  16.179 ? 264 GLY D H    1 c 
ATOM   5156 H HA2  . GLY B 1 96  ? 15.141  52.477  -13.54  0.33  16.008 ? 264 GLY D HA2  1 c 
ATOM   5157 H HA3  . GLY B 1 96  ? 15.146  50.887  -13.586 0.33  16.008 ? 264 GLY D HA3  1 c 
ATOM   5158 N N    . ALA B 1 97  ? 12.585  51.706  -12.079 0.33  17.206 ? 265 ALA D N    1 ? 
ATOM   5159 C CA   . ALA B 1 97  ? 11.142  51.645  -12.059 0.33  18.315 ? 265 ALA D CA   1 ? 
ATOM   5160 C C    . ALA B 1 97  ? 10.655  52.257  -10.759 0.33  18.49  ? 265 ALA D C    1 ? 
ATOM   5161 O O    . ALA B 1 97  ? 11.398  52.361  -9.795  0.33  15.837 ? 265 ALA D O    1 ? 
ATOM   5162 C CB   . ALA B 1 97  ? 10.678  50.206  -12.177 0.33  18.669 ? 265 ALA D CB   1 ? 
ATOM   5163 H H    . ALA B 1 97  ? 13.035  51.773  -11.287 0.33  17.166 ? 265 ALA D H    1 c 
ATOM   5164 H HA   . ALA B 1 97  ? 10.786  52.179  -12.821 0.33  18.188 ? 265 ALA D HA   1 c 
ATOM   5165 H HB1  . ALA B 1 97  ? 10.998  49.827  -13.012 0.33  18.563 ? 265 ALA D HB1  1 c 
ATOM   5166 H HB2  . ALA B 1 97  ? 11.028  49.688  -11.433 0.33  18.563 ? 265 ALA D HB2  1 c 
ATOM   5167 H HB3  . ALA B 1 97  ? 9.706   50.174  -12.161 0.33  18.563 ? 265 ALA D HB3  1 c 
ATOM   5168 N N    . ILE B 1 98  ? 9.367   52.586  -10.738 0.33  19.81  ? 266 ILE D N    1 ? 
ATOM   5169 C CA   . ILE B 1 98  ? 8.717   53.033  -9.522  0.33  21.01  ? 266 ILE D CA   1 ? 
ATOM   5170 C C    . ILE B 1 98  ? 7.444   52.217  -9.351  0.33  21.86  ? 266 ILE D C    1 ? 
ATOM   5171 O O    . ILE B 1 98  ? 6.759   51.903  -10.325 0.33  23.154 ? 266 ILE D O    1 ? 
ATOM   5172 C CB   . ILE B 1 98  ? 8.441   54.543  -9.559  0.33  22.208 ? 266 ILE D CB   1 ? 
ATOM   5173 C CG1  . ILE B 1 98  ? 7.881   55.073  -8.228  0.33  23.449 ? 266 ILE D CG1  1 ? 
ATOM   5174 C CG2  . ILE B 1 98  ? 7.536   54.91   -10.733 0.33  21.619 ? 266 ILE D CG2  1 ? 
ATOM   5175 C CD1  . ILE B 1 98  ? 8.869   55.039  -7.087  0.33  24.92  ? 266 ILE D CD1  1 ? 
ATOM   5176 H H    . ILE B 1 98  ? 8.876   52.531  -11.507 0.33  19.748 ? 266 ILE D H    1 c 
ATOM   5177 H HA   . ILE B 1 98  ? 9.311   52.846  -8.769  0.33  21.137 ? 266 ILE D HA   1 c 
ATOM   5178 H HB   . ILE B 1 98  ? 9.299   54.988  -9.705  0.33  22.092 ? 266 ILE D HB   1 c 
ATOM   5179 H HG12 . ILE B 1 98  ? 7.584   55.996  -8.359  0.33  23.491 ? 266 ILE D HG12 1 c 
ATOM   5180 H HG13 . ILE B 1 98  ? 7.099   54.539  -7.982  0.33  23.491 ? 266 ILE D HG13 1 c 
ATOM   5181 H HG21 . ILE B 1 98  ? 7.371   55.868  -10.731 0.33  21.79  ? 266 ILE D HG21 1 c 
ATOM   5182 H HG22 . ILE B 1 98  ? 6.691   54.437  -10.654 0.33  21.79  ? 266 ILE D HG22 1 c 
ATOM   5183 H HG23 . ILE B 1 98  ? 7.968   54.66   -11.568 0.33  21.79  ? 266 ILE D HG23 1 c 
ATOM   5184 H HD11 . ILE B 1 98  ? 9.159   54.12   -6.932  0.33  24.475 ? 266 ILE D HD11 1 c 
ATOM   5185 H HD12 . ILE B 1 98  ? 8.446   55.385  -6.278  0.33  24.475 ? 266 ILE D HD12 1 c 
ATOM   5186 H HD13 . ILE B 1 98  ? 9.643   55.59   -7.308  0.33  24.475 ? 266 ILE D HD13 1 c 
ATOM   5187 N N    . GLU B 1 99  ? 7.189   51.889  -8.084  0.33  22.96  ? 267 GLU D N    1 ? 
ATOM   5188 C CA   . GLU B 1 99  ? 6.033   51.122  -7.662  0.33  22.96  ? 267 GLU D CA   1 ? 
ATOM   5189 C C    . GLU B 1 99  ? 5.007   52.066  -7.046  0.33  23.442 ? 267 GLU D C    1 ? 
ATOM   5190 O O    . GLU B 1 99  ? 5.341   53.009  -6.327  0.33  24.819 ? 267 GLU D O    1 ? 
ATOM   5191 C CB   . GLU B 1 99  ? 6.432   50.022  -6.67   0.33  23.099 ? 267 GLU D CB   1 ? 
ATOM   5192 H H    . GLU B 1 99  ? 7.778   52.163  -7.441  0.33  22.694 ? 267 GLU D H    1 c 
ATOM   5193 H HA   . GLU B 1 99  ? 5.632   50.698  -8.464  0.33  23.073 ? 267 GLU D HA   1 c 
ATOM   5194 N N    . GLU B 1 100 ? 3.74    51.745  -7.318  0.33  26.099 ? 268 GLU D N    1 ? 
ATOM   5195 C CA   . GLU B 1 100 ? 2.598   52.55   -6.925  0.33  26.629 ? 268 GLU D CA   1 ? 
ATOM   5196 C C    . GLU B 1 100 ? 2.526   52.702  -5.41   0.33  26.905 ? 268 GLU D C    1 ? 
ATOM   5197 O O    . GLU B 1 100 ? 1.993   53.696  -4.917  0.33  27.896 ? 268 GLU D O    1 ? 
ATOM   5198 C CB   . GLU B 1 100 ? 1.325   51.909  -7.489  0.33  27.867 ? 268 GLU D CB   1 ? 
ATOM   5199 H H    . GLU B 1 100 ? 3.581   50.972  -7.78   0.33  25.557 ? 268 GLU D H    1 c 
ATOM   5200 H HA   . GLU B 1 100 ? 2.702   53.45   -7.326  0.33  26.795 ? 268 GLU D HA   1 c 
ATOM   5201 N N    . TYR B 1 101 ? 3.045   51.72   -4.667  0.33  27.297 ? 269 TYR D N    1 ? 
ATOM   5202 C CA   . TYR B 1 101 ? 2.888   51.741  -3.223  0.33  28.195 ? 269 TYR D CA   1 ? 
ATOM   5203 C C    . TYR B 1 101 ? 3.993   52.584  -2.588  0.33  25.506 ? 269 TYR D C    1 ? 
ATOM   5204 O O    . TYR B 1 101 ? 3.953   52.826  -1.387  0.33  24.778 ? 269 TYR D O    1 ? 
ATOM   5205 C CB   . TYR B 1 101 ? 2.835   50.321  -2.645  0.33  30.218 ? 269 TYR D CB   1 ? 
ATOM   5206 C CG   . TYR B 1 101 ? 3.955   49.401  -3.105  0.33  31.684 ? 269 TYR D CG   1 ? 
ATOM   5207 C CD1  . TYR B 1 101 ? 5.196   49.414  -2.48   0.33  30.867 ? 269 TYR D CD1  1 ? 
ATOM   5208 C CD2  . TYR B 1 101 ? 3.775   48.521  -4.168  0.33  32.103 ? 269 TYR D CD2  1 ? 
ATOM   5209 C CE1  . TYR B 1 101 ? 6.222   48.586  -2.902  0.33  30.714 ? 269 TYR D CE1  1 ? 
ATOM   5210 C CE2  . TYR B 1 101 ? 4.794   47.691  -4.597  0.33  32.182 ? 269 TYR D CE2  1 ? 
ATOM   5211 C CZ   . TYR B 1 101 ? 6.019   47.718  -3.958  0.33  31.448 ? 269 TYR D CZ   1 ? 
ATOM   5212 O OH   . TYR B 1 101 ? 7.034   46.91   -4.387  0.33  31.456 ? 269 TYR D OH   1 ? 
ATOM   5213 H H    . TYR B 1 101 ? 3.501   51.032  -5.062  0.33  27.401 ? 269 TYR D H    1 c 
ATOM   5214 H HA   . TYR B 1 101 ? 2.019   52.181  -3.023  0.33  27.857 ? 269 TYR D HA   1 c 
ATOM   5215 H HB2  . TYR B 1 101 ? 2.861   50.384  -1.664  0.33  30.07  ? 269 TYR D HB2  1 c 
ATOM   5216 H HB3  . TYR B 1 101 ? 1.973   49.917  -2.893  0.33  30.07  ? 269 TYR D HB3  1 c 
ATOM   5217 H HD1  . TYR B 1 101 ? 5.345   50.003  -1.757  0.33  31.028 ? 269 TYR D HD1  1 c 
ATOM   5218 H HD2  . TYR B 1 101 ? 2.941   48.495  -4.611  0.33  31.995 ? 269 TYR D HD2  1 c 
ATOM   5219 H HE1  . TYR B 1 101 ? 7.058   48.61   -2.468  0.33  30.938 ? 269 TYR D HE1  1 c 
ATOM   5220 H HE2  . TYR B 1 101 ? 4.653   47.104  -5.321  0.33  31.97  ? 269 TYR D HE2  1 c 
ATOM   5221 N N    . ARG B 1 102 ? 4.953   53.066  -3.389  0.33  25.175 ? 270 ARG D N    1 ? 
ATOM   5222 C CA   . ARG B 1 102 ? 6.129   53.713  -2.821  0.33  24.422 ? 270 ARG D CA   1 ? 
ATOM   5223 C C    . ARG B 1 102 ? 5.827   55.164  -2.469  0.33  25.207 ? 270 ARG D C    1 ? 
ATOM   5224 O O    . ARG B 1 102 ? 5.027   55.819  -3.13   0.33  28.657 ? 270 ARG D O    1 ? 
ATOM   5225 C CB   . ARG B 1 102 ? 7.32    53.713  -3.779  0.33  22.508 ? 270 ARG D CB   1 ? 
ATOM   5226 C CG   . ARG B 1 102 ? 7.829   52.333  -4.131  0.33  21.828 ? 270 ARG D CG   1 ? 
ATOM   5227 C CD   . ARG B 1 102 ? 8.511   51.685  -2.944  0.33  21.025 ? 270 ARG D CD   1 ? 
ATOM   5228 N NE   . ARG B 1 102 ? 9.169   50.442  -3.347  0.33  20.24  ? 270 ARG D NE   1 ? 
ATOM   5229 C CZ   . ARG B 1 102 ? 9.66    49.562  -2.479  0.33  20.476 ? 270 ARG D CZ   1 ? 
ATOM   5230 N NH1  . ARG B 1 102 ? 9.662   49.811  -1.169  0.33  19.214 ? 270 ARG D NH1  1 ? 
ATOM   5231 N NH2  . ARG B 1 102 ? 10.158  48.427  -2.946  0.33  21.277 ? 270 ARG D NH2  1 ? 
ATOM   5232 H H    . ARG B 1 102 ? 4.876   52.992  -4.297  0.33  25.083 ? 270 ARG D H    1 c 
ATOM   5233 H HA   . ARG B 1 102 ? 6.381   53.231  -1.993  0.33  24.346 ? 270 ARG D HA   1 c 
ATOM   5234 H HB2  . ARG B 1 102 ? 7.059   54.173  -4.606  0.33  22.768 ? 270 ARG D HB2  1 c 
ATOM   5235 H HB3  . ARG B 1 102 ? 8.051   54.225  -3.372  0.33  22.768 ? 270 ARG D HB3  1 c 
ATOM   5236 H HG2  . ARG B 1 102 ? 7.078   51.77   -4.418  0.33  21.794 ? 270 ARG D HG2  1 c 
ATOM   5237 H HG3  . ARG B 1 102 ? 8.468   52.399  -4.873  0.33  21.794 ? 270 ARG D HG3  1 c 
ATOM   5238 H HD2  . ARG B 1 102 ? 9.176   52.299  -2.571  0.33  21.014 ? 270 ARG D HD2  1 c 
ATOM   5239 H HD3  . ARG B 1 102 ? 7.849   51.491  -2.249  0.33  21.014 ? 270 ARG D HD3  1 c 
ATOM   5240 H HE   . ARG B 1 102 ? 9.244   50.268  -4.197  0.33  20.474 ? 270 ARG D HE   1 c 
ATOM   5241 H HH11 . ARG B 1 102 ? 9.335   50.575  -0.866  0.33  19.593 ? 270 ARG D HH11 1 c 
ATOM   5242 H HH12 . ARG B 1 102 ? 9.989   49.21   -0.608  0.33  19.593 ? 270 ARG D HH12 1 c 
ATOM   5243 H HH21 . ARG B 1 102 ? 10.154  48.27   -3.816  0.33  21.027 ? 270 ARG D HH21 1 c 
ATOM   5244 H HH22 . ARG B 1 102 ? 10.493  47.831  -2.385  0.33  21.027 ? 270 ARG D HH22 1 c 
ATOM   5245 N N    . PRO B 1 103 ? 6.491   55.733  -1.443  0.33  26.402 ? 271 PRO D N    1 ? 
ATOM   5246 C CA   . PRO B 1 103 ? 6.251   57.129  -1.071  0.33  27.11  ? 271 PRO D CA   1 ? 
ATOM   5247 C C    . PRO B 1 103 ? 6.615   58.131  -2.166  0.33  27.883 ? 271 PRO D C    1 ? 
ATOM   5248 O O    . PRO B 1 103 ? 6.059   59.224  -2.213  0.33  28.903 ? 271 PRO D O    1 ? 
ATOM   5249 C CB   . PRO B 1 103 ? 7.112   57.312  0.185   0.33  26.774 ? 271 PRO D CB   1 ? 
ATOM   5250 C CG   . PRO B 1 103 ? 8.19    56.25   0.046   0.33  27.898 ? 271 PRO D CG   1 ? 
ATOM   5251 C CD   . PRO B 1 103 ? 7.463   55.056  -0.566  0.33  26.203 ? 271 PRO D CD   1 ? 
ATOM   5252 H HA   . PRO B 1 103 ? 5.296   57.233  -0.831  0.33  27.048 ? 271 PRO D HA   1 c 
ATOM   5253 H HB2  . PRO B 1 103 ? 7.508   58.214  0.213   0.33  27.099 ? 271 PRO D HB2  1 c 
ATOM   5254 H HB3  . PRO B 1 103 ? 6.579   57.168  1.002   0.33  27.099 ? 271 PRO D HB3  1 c 
ATOM   5255 H HG2  . PRO B 1 103 ? 8.912   56.558  -0.541  0.33  27.254 ? 271 PRO D HG2  1 c 
ATOM   5256 H HG3  . PRO B 1 103 ? 8.568   56.018  0.92    0.33  27.254 ? 271 PRO D HG3  1 c 
ATOM   5257 H HD2  . PRO B 1 103 ? 8.078   54.488  -1.081  0.33  26.616 ? 271 PRO D HD2  1 c 
ATOM   5258 H HD3  . PRO B 1 103 ? 7.013   54.519  0.123   0.33  26.616 ? 271 PRO D HD3  1 c 
ATOM   5259 N N    . GLU B 1 104 ? 7.554   57.76   -3.044  0.33  28.377 ? 272 GLU D N    1 ? 
ATOM   5260 C CA   . GLU B 1 104 ? 8.023   58.68   -4.065  0.33  27.29  ? 272 GLU D CA   1 ? 
ATOM   5261 C C    . GLU B 1 104 ? 7.08    58.697  -5.265  0.33  28.002 ? 272 GLU D C    1 ? 
ATOM   5262 O O    . GLU B 1 104 ? 7.26    59.526  -6.141  0.33  27.533 ? 272 GLU D O    1 ? 
ATOM   5263 C CB   . GLU B 1 104 ? 9.437   58.348  -4.541  0.33  25.418 ? 272 GLU D CB   1 ? 
ATOM   5264 C CG   . GLU B 1 104 ? 10.474  58.361  -3.421  0.33  24.244 ? 272 GLU D CG   1 ? 
ATOM   5265 C CD   . GLU B 1 104 ? 10.821  56.998  -2.85   0.33  23.204 ? 272 GLU D CD   1 ? 
ATOM   5266 O OE1  . GLU B 1 104 ? 9.92    56.151  -2.854  0.33  21.082 ? 272 GLU D OE1  1 ? 
ATOM   5267 O OE2  . GLU B 1 104 ? 11.945  56.788  -2.36   0.33  23.133 ? 272 GLU D OE2  1 ? 
ATOM   5268 H H    . GLU B 1 104 ? 7.908   56.918  -3.005  0.33  28.011 ? 272 GLU D H    1 c 
ATOM   5269 H HA   . GLU B 1 104 ? 8.038   59.589  -3.671  0.33  27.271 ? 272 GLU D HA   1 c 
ATOM   5270 H HB2  . GLU B 1 104 ? 9.43    57.461  -4.958  0.33  25.556 ? 272 GLU D HB2  1 c 
ATOM   5271 H HB3  . GLU B 1 104 ? 9.7     58.997  -5.227  0.33  25.556 ? 272 GLU D HB3  1 c 
ATOM   5272 H HG2  . GLU B 1 104 ? 11.298  58.773  -3.758  0.33  24.26  ? 272 GLU D HG2  1 c 
ATOM   5273 H HG3  . GLU B 1 104 ? 10.143  58.926  -2.691  0.33  24.26  ? 272 GLU D HG3  1 c 
ATOM   5274 N N    . TRP B 1 105 ? 6.075   57.811  -5.308  0.33  28.255 ? 273 TRP D N    1 ? 
ATOM   5275 C CA   . TRP B 1 105 ? 5.217   57.69   -6.479  0.33  29.74  ? 273 TRP D CA   1 ? 
ATOM   5276 C C    . TRP B 1 105 ? 4.667   59.054  -6.892  0.33  30.152 ? 273 TRP D C    1 ? 
ATOM   5277 O O    . TRP B 1 105 ? 4.69    59.39   -8.073  0.33  31.09  ? 273 TRP D O    1 ? 
ATOM   5278 C CB   . TRP B 1 105 ? 4.062   56.717  -6.215  0.33  28.201 ? 273 TRP D CB   1 ? 
ATOM   5279 C CG   . TRP B 1 105 ? 3.086   56.628  -7.359  0.33  27.916 ? 273 TRP D CG   1 ? 
ATOM   5280 C CD1  . TRP B 1 105 ? 1.904   57.299  -7.506  0.33  29.512 ? 273 TRP D CD1  1 ? 
ATOM   5281 C CD2  . TRP B 1 105 ? 3.222   55.789  -8.525  0.33  28.296 ? 273 TRP D CD2  1 ? 
ATOM   5282 N NE1  . TRP B 1 105 ? 1.309   56.952  -8.687  0.33  30.337 ? 273 TRP D NE1  1 ? 
ATOM   5283 C CE2  . TRP B 1 105 ? 2.087   56.023  -9.331  0.33  28.769 ? 273 TRP D CE2  1 ? 
ATOM   5284 C CE3  . TRP B 1 105 ? 4.183   54.876  -8.966  0.33  27.789 ? 273 TRP D CE3  1 ? 
ATOM   5285 C CZ2  . TRP B 1 105 ? 1.891   55.371  -10.541 0.33  26.345 ? 273 TRP D CZ2  1 ? 
ATOM   5286 C CZ3  . TRP B 1 105 ? 3.986   54.23   -10.163 0.33  26.182 ? 273 TRP D CZ3  1 ? 
ATOM   5287 C CH2  . TRP B 1 105 ? 2.857   54.479  -10.937 0.33  27.858 ? 273 TRP D CH2  1 ? 
ATOM   5288 H H    . TRP B 1 105 ? 5.921   57.268  -4.589  0.33  28.521 ? 273 TRP D H    1 c 
ATOM   5289 H HA   . TRP B 1 105 ? 5.763   57.33   -7.229  0.33  29.234 ? 273 TRP D HA   1 c 
ATOM   5290 H HB2  . TRP B 1 105 ? 4.436   55.827  -6.045  0.33  28.475 ? 273 TRP D HB2  1 c 
ATOM   5291 H HB3  . TRP B 1 105 ? 3.584   57.01   -5.41   0.33  28.475 ? 273 TRP D HB3  1 c 
ATOM   5292 H HD1  . TRP B 1 105 ? 1.554   57.929  -6.897  0.33  29.306 ? 273 TRP D HD1  1 c 
ATOM   5293 H HE1  . TRP B 1 105 ? 0.545   57.261  -8.977  0.33  29.723 ? 273 TRP D HE1  1 c 
ATOM   5294 H HE3  . TRP B 1 105 ? 4.949   54.701  -8.447  0.33  27.524 ? 273 TRP D HE3  1 c 
ATOM   5295 H HZ2  . TRP B 1 105 ? 1.128   55.537  -11.068 0.33  27.251 ? 273 TRP D HZ2  1 c 
ATOM   5296 H HZ3  . TRP B 1 105 ? 4.629   53.611  -10.468 0.33  26.956 ? 273 TRP D HZ3  1 c 
ATOM   5297 H HH2  . TRP B 1 105 ? 2.751   54.024  -11.754 0.33  27.124 ? 273 TRP D HH2  1 c 
ATOM   5298 N N    . SER B 1 106 ? 4.202   59.826  -5.901  0.33  33.091 ? 274 SER D N    1 ? 
ATOM   5299 C CA   . SER B 1 106 ? 3.55    61.111  -6.117  0.33  34.459 ? 274 SER D CA   1 ? 
ATOM   5300 C C    . SER B 1 106 ? 4.511   62.157  -6.675  0.33  34.156 ? 274 SER D C    1 ? 
ATOM   5301 O O    . SER B 1 106 ? 4.076   63.151  -7.251  0.33  33.564 ? 274 SER D O    1 ? 
ATOM   5302 C CB   . SER B 1 106 ? 2.92    61.612  -4.84   0.33  36.095 ? 274 SER D CB   1 ? 
ATOM   5303 H H    . SER B 1 106 ? 4.3     59.532  -5.041  0.33  32.663 ? 274 SER D H    1 c 
ATOM   5304 H HA   . SER B 1 106 ? 2.829   60.975  -6.783  0.33  34.429 ? 274 SER D HA   1 c 
ATOM   5305 N N    . GLN B 1 107 ? 5.816   61.942  -6.48   0.33  37.01  ? 275 GLN D N    1 ? 
ATOM   5306 C CA   . GLN B 1 107 ? 6.83    62.859  -6.973  0.33  34.437 ? 275 GLN D CA   1 ? 
ATOM   5307 C C    . GLN B 1 107 ? 7.219   62.518  -8.406  0.33  32.657 ? 275 GLN D C    1 ? 
ATOM   5308 O O    . GLN B 1 107 ? 8.031   63.222  -8.994  0.33  37.808 ? 275 GLN D O    1 ? 
ATOM   5309 C CB   . GLN B 1 107 ? 8.094   62.792  -6.12   0.33  36.009 ? 275 GLN D CB   1 ? 
ATOM   5310 H H    . GLN B 1 107 ? 6.083   61.197  -6.023  0.33  35.724 ? 275 GLN D H    1 c 
ATOM   5311 H HA   . GLN B 1 107 ? 6.462   63.779  -6.949  0.33  34.869 ? 275 GLN D HA   1 c 
ATOM   5312 N N    . VAL B 1 108 ? 6.685   61.425  -8.951  0.33  32.838 ? 276 VAL D N    1 ? 
ATOM   5313 C CA   . VAL B 1 108 ? 7.091   60.981  -10.274 0.33  33.472 ? 276 VAL D CA   1 ? 
ATOM   5314 C C    . VAL B 1 108 ? 6.017   61.382  -11.281 0.33  36.558 ? 276 VAL D C    1 ? 
ATOM   5315 O O    . VAL B 1 108 ? 4.952   60.774  -11.34  0.33  38.617 ? 276 VAL D O    1 ? 
ATOM   5316 C CB   . VAL B 1 108 ? 7.379   59.469  -10.321 0.33  33.634 ? 276 VAL D CB   1 ? 
ATOM   5317 C CG1  . VAL B 1 108 ? 7.548   58.954  -11.748 0.33  34.29  ? 276 VAL D CG1  1 ? 
ATOM   5318 C CG2  . VAL B 1 108 ? 8.599   59.122  -9.483  0.33  35.062 ? 276 VAL D CG2  1 ? 
ATOM   5319 H H    . VAL B 1 108 ? 6.057   60.945  -8.492  0.33  32.936 ? 276 VAL D H    1 c 
ATOM   5320 H HA   . VAL B 1 108 ? 7.914   61.452  -10.507 0.33  33.926 ? 276 VAL D HA   1 c 
ATOM   5321 H HB   . VAL B 1 108 ? 6.6     59.013  -9.925  0.33  33.988 ? 276 VAL D HB   1 c 
ATOM   5322 H HG11 . VAL B 1 108 ? 8.296   59.409  -12.171 0.33  34.096 ? 276 VAL D HG11 1 c 
ATOM   5323 H HG12 . VAL B 1 108 ? 6.737   59.127  -12.254 0.33  34.096 ? 276 VAL D HG12 1 c 
ATOM   5324 H HG13 . VAL B 1 108 ? 7.72    57.998  -11.73  0.33  34.096 ? 276 VAL D HG13 1 c 
ATOM   5325 H HG21 . VAL B 1 108 ? 8.763   58.165  -9.529  0.33  34.634 ? 276 VAL D HG21 1 c 
ATOM   5326 H HG22 . VAL B 1 108 ? 8.442   59.378  -8.558  0.33  34.634 ? 276 VAL D HG22 1 c 
ATOM   5327 H HG23 . VAL B 1 108 ? 9.374   59.6    -9.823  0.33  34.634 ? 276 VAL D HG23 1 c 
ATOM   5328 N N    . PRO B 1 109 ? 6.273   62.405  -12.123 0.33  38.355 ? 277 PRO D N    1 ? 
ATOM   5329 C CA   . PRO B 1 109 ? 5.28    62.834  -13.105 0.33  39.348 ? 277 PRO D CA   1 ? 
ATOM   5330 C C    . PRO B 1 109 ? 5.122   61.843  -14.254 0.33  38.228 ? 277 PRO D C    1 ? 
ATOM   5331 O O    . PRO B 1 109 ? 5.981   60.992  -14.494 0.33  38.015 ? 277 PRO D O    1 ? 
ATOM   5332 C CB   . PRO B 1 109 ? 5.824   64.191  -13.563 0.33  39.754 ? 277 PRO D CB   1 ? 
ATOM   5333 C CG   . PRO B 1 109 ? 7.319   64.054  -13.404 0.33  39.044 ? 277 PRO D CG   1 ? 
ATOM   5334 C CD   . PRO B 1 109 ? 7.509   63.2    -12.162 0.33  38.385 ? 277 PRO D CD   1 ? 
ATOM   5335 H HA   . PRO B 1 109 ? 4.411   62.962  -12.65  0.33  39.021 ? 277 PRO D HA   1 c 
ATOM   5336 H HB2  . PRO B 1 109 ? 5.584   64.368  -14.502 0.33  39.502 ? 277 PRO D HB2  1 c 
ATOM   5337 H HB3  . PRO B 1 109 ? 5.474   64.919  -12.998 0.33  39.502 ? 277 PRO D HB3  1 c 
ATOM   5338 H HG2  . PRO B 1 109 ? 7.713   63.617  -14.188 0.33  39.054 ? 277 PRO D HG2  1 c 
ATOM   5339 H HG3  . PRO B 1 109 ? 7.738   64.932  -13.288 0.33  39.054 ? 277 PRO D HG3  1 c 
ATOM   5340 H HD2  . PRO B 1 109 ? 8.3     62.623  -12.246 0.33  38.524 ? 277 PRO D HD2  1 c 
ATOM   5341 H HD3  . PRO B 1 109 ? 7.598   63.759  -11.358 0.33  38.524 ? 277 PRO D HD3  1 c 
ATOM   5342 N N    . ALA B 1 110 ? 4.003   61.991  -14.966 0.33  36.153 ? 278 ALA D N    1 ? 
ATOM   5343 C CA   . ALA B 1 110 ? 3.666   61.122  -16.076 0.33  37.804 ? 278 ALA D CA   1 ? 
ATOM   5344 C C    . ALA B 1 110 ? 4.812   61.096  -17.078 0.33  37.937 ? 278 ALA D C    1 ? 
ATOM   5345 O O    . ALA B 1 110 ? 5.051   60.071  -17.698 0.33  38.992 ? 278 ALA D O    1 ? 
ATOM   5346 C CB   . ALA B 1 110 ? 2.375   61.586  -16.716 0.33  38.395 ? 278 ALA D CB   1 ? 
ATOM   5347 H H    . ALA B 1 110 ? 3.426   62.665  -14.748 0.33  37.009 ? 278 ALA D H    1 c 
ATOM   5348 H HA   . ALA B 1 110 ? 3.541   60.199  -15.721 0.33  37.606 ? 278 ALA D HA   1 c 
ATOM   5349 H HB1  . ALA B 1 110 ? 1.659   61.569  -16.059 0.33  38.219 ? 278 ALA D HB1  1 c 
ATOM   5350 H HB2  . ALA B 1 110 ? 2.482   62.492  -17.051 0.33  38.219 ? 278 ALA D HB2  1 c 
ATOM   5351 H HB3  . ALA B 1 110 ? 2.146   60.996  -17.455 0.33  38.219 ? 278 ALA D HB3  1 c 
ATOM   5352 N N    . ASP B 1 111 ? 5.516   62.226  -17.219 0.33  37.643 ? 279 ASP D N    1 ? 
ATOM   5353 C CA   . ASP B 1 111 ? 6.577   62.37   -18.206 0.33  38.555 ? 279 ASP D CA   1 ? 
ATOM   5354 C C    . ASP B 1 111 ? 7.774   61.477  -17.872 0.33  36.203 ? 279 ASP D C    1 ? 
ATOM   5355 O O    . ASP B 1 111 ? 8.615   61.235  -18.74  0.33  35.331 ? 279 ASP D O    1 ? 
ATOM   5356 C CB   . ASP B 1 111 ? 7.024   63.82   -18.336 0.33  36.912 ? 279 ASP D CB   1 ? 
ATOM   5357 H H    . ASP B 1 111 ? 5.325   62.936  -16.676 0.33  37.917 ? 279 ASP D H    1 c 
ATOM   5358 H HA   . ASP B 1 111 ? 6.219   62.092  -19.079 0.33  37.632 ? 279 ASP D HA   1 c 
ATOM   5359 N N    . LEU B 1 112 ? 7.874   61.017  -16.616 0.33  37.519 ? 280 LEU D N    1 ? 
ATOM   5360 C CA   . LEU B 1 112 ? 8.968   60.147  -16.21  0.33  35.749 ? 280 LEU D CA   1 ? 
ATOM   5361 C C    . LEU B 1 112 ? 8.612   58.681  -16.448 0.33  34.983 ? 280 LEU D C    1 ? 
ATOM   5362 O O    . LEU B 1 112 ? 9.512   57.855  -16.511 0.33  32.59  ? 280 LEU D O    1 ? 
ATOM   5363 C CB   . LEU B 1 112 ? 9.354   60.355  -14.746 0.33  37.806 ? 280 LEU D CB   1 ? 
ATOM   5364 C CG   . LEU B 1 112 ? 10.345  61.486  -14.449 0.33  37.673 ? 280 LEU D CG   1 ? 
ATOM   5365 C CD1  . LEU B 1 112 ? 10.868  61.342  -13.024 0.33  37.366 ? 280 LEU D CD1  1 ? 
ATOM   5366 C CD2  . LEU B 1 112 ? 11.499  61.539  -15.443 0.33  38.164 ? 280 LEU D CD2  1 ? 
ATOM   5367 H H    . LEU B 1 112 ? 7.242   61.253  -15.998 0.33  36.799 ? 280 LEU D H    1 c 
ATOM   5368 H HA   . LEU B 1 112 ? 9.751   60.365  -16.776 0.33  36.313 ? 280 LEU D HA   1 c 
ATOM   5369 H HB2  . LEU B 1 112 ? 8.529   60.525  -14.234 0.33  37.296 ? 280 LEU D HB2  1 c 
ATOM   5370 H HB3  . LEU B 1 112 ? 9.737   59.512  -14.409 0.33  37.296 ? 280 LEU D HB3  1 c 
ATOM   5371 H HG   . LEU B 1 112 ? 9.854   62.346  -14.507 0.33  37.731 ? 280 LEU D HG   1 c 
ATOM   5372 H HD11 . LEU B 1 112 ? 10.126  61.387  -12.399 0.33  37.456 ? 280 LEU D HD11 1 c 
ATOM   5373 H HD12 . LEU B 1 112 ? 11.495  62.061  -12.834 0.33  37.456 ? 280 LEU D HD12 1 c 
ATOM   5374 H HD13 . LEU B 1 112 ? 11.32   60.487  -12.929 0.33  37.456 ? 280 LEU D HD13 1 c 
ATOM   5375 H HD21 . LEU B 1 112 ? 11.15   61.68   -16.339 0.33  38.019 ? 280 LEU D HD21 1 c 
ATOM   5376 H HD22 . LEU B 1 112 ? 11.991  60.702  -15.415 0.33  38.019 ? 280 LEU D HD22 1 c 
ATOM   5377 H HD23 . LEU B 1 112 ? 12.094  62.272  -15.21  0.33  38.019 ? 280 LEU D HD23 1 c 
ATOM   5378 N N    . LYS B 1 113 ? 7.315   58.369  -16.583 0.33  33.627 ? 281 LYS D N    1 ? 
ATOM   5379 C CA   . LYS B 1 113 ? 6.876   56.988  -16.699 0.33  34.069 ? 281 LYS D CA   1 ? 
ATOM   5380 C C    . LYS B 1 113 ? 6.948   56.518  -18.149 0.33  32.7   ? 281 LYS D C    1 ? 
ATOM   5381 O O    . LYS B 1 113 ? 6.769   57.294  -19.082 0.33  34.313 ? 281 LYS D O    1 ? 
ATOM   5382 C CB   . LYS B 1 113 ? 5.477   56.839  -16.097 0.33  33.583 ? 281 LYS D CB   1 ? 
ATOM   5383 C CG   . LYS B 1 113 ? 5.426   57.174  -14.617 0.33  32.198 ? 281 LYS D CG   1 ? 
ATOM   5384 H H    . LYS B 1 113 ? 6.69    59.036  -16.604 0.33  34.045 ? 281 LYS D H    1 c 
ATOM   5385 H HA   . LYS B 1 113 ? 7.495   56.428  -16.165 0.33  33.639 ? 281 LYS D HA   1 c 
ATOM   5386 H HB2  . LYS B 1 113 ? 4.857   57.431  -16.576 0.33  33.369 ? 281 LYS D HB2  1 c 
ATOM   5387 H HB3  . LYS B 1 113 ? 5.17    55.915  -16.222 0.33  33.369 ? 281 LYS D HB3  1 c 
ATOM   5388 N N    . LEU B 1 114 ? 7.252   55.234  -18.331 0.33  31.904 ? 282 LEU D N    1 ? 
ATOM   5389 C CA   . LEU B 1 114 ? 7.458   54.692  -19.66  0.33  31.707 ? 282 LEU D CA   1 ? 
ATOM   5390 C C    . LEU B 1 114 ? 6.523   53.516  -19.922 0.33  31.67  ? 282 LEU D C    1 ? 
ATOM   5391 O O    . LEU B 1 114 ? 6.563   52.94   -21.005 0.33  30.165 ? 282 LEU D O    1 ? 
ATOM   5392 C CB   . LEU B 1 114 ? 8.914   54.281  -19.848 0.33  32.706 ? 282 LEU D CB   1 ? 
ATOM   5393 C CG   . LEU B 1 114 ? 9.908   55.435  -20.008 0.33  34.671 ? 282 LEU D CG   1 ? 
ATOM   5394 C CD1  . LEU B 1 114 ? 11.341  54.942  -20.023 0.33  34.35  ? 282 LEU D CD1  1 ? 
ATOM   5395 C CD2  . LEU B 1 114 ? 9.587   56.203  -21.286 0.33  35.949 ? 282 LEU D CD2  1 ? 
ATOM   5396 H H    . LEU B 1 114 ? 7.334   54.681  -17.608 0.33  32.047 ? 282 LEU D H    1 c 
ATOM   5397 H HA   . LEU B 1 114 ? 7.243   55.404  -20.314 0.33  31.918 ? 282 LEU D HA   1 c 
ATOM   5398 H HB2  . LEU B 1 114 ? 9.185   53.742  -19.069 0.33  32.907 ? 282 LEU D HB2  1 c 
ATOM   5399 H HB3  . LEU B 1 114 ? 8.972   53.707  -20.646 0.33  32.907 ? 282 LEU D HB3  1 c 
ATOM   5400 H HG   . LEU B 1 114 ? 9.799   56.051  -19.238 0.33  34.471 ? 282 LEU D HG   1 c 
ATOM   5401 H HD11 . LEU B 1 114 ? 11.533  54.474  -19.193 0.33  34.445 ? 282 LEU D HD11 1 c 
ATOM   5402 H HD12 . LEU B 1 114 ? 11.945  55.698  -20.114 0.33  34.445 ? 282 LEU D HD12 1 c 
ATOM   5403 H HD13 . LEU B 1 114 ? 11.469  54.335  -20.772 0.33  34.445 ? 282 LEU D HD13 1 c 
ATOM   5404 H HD21 . LEU B 1 114 ? 8.684   56.56   -21.232 0.33  35.568 ? 282 LEU D HD21 1 c 
ATOM   5405 H HD22 . LEU B 1 114 ? 9.652   55.606  -22.05  0.33  35.568 ? 282 LEU D HD22 1 c 
ATOM   5406 H HD23 . LEU B 1 114 ? 10.218  56.935  -21.393 0.33  35.568 ? 282 LEU D HD23 1 c 
ATOM   5407 N N    . GLY B 1 115 ? 5.702   53.142  -18.935 0.33  31.679 ? 283 GLY D N    1 ? 
ATOM   5408 C CA   . GLY B 1 115 ? 4.782   52.032  -19.135 0.33  33.619 ? 283 GLY D CA   1 ? 
ATOM   5409 C C    . GLY B 1 115 ? 4.9     50.963  -18.05  0.33  34.711 ? 283 GLY D C    1 ? 
ATOM   5410 O O    . GLY B 1 115 ? 5.877   50.923  -17.295 0.33  32.496 ? 283 GLY D O    1 ? 
ATOM   5411 H H    . GLY B 1 115 ? 5.714   53.579  -18.132 0.33  32.101 ? 283 GLY D H    1 c 
ATOM   5412 H HA2  . GLY B 1 115 ? 3.861   52.382  -19.15  0.33  33.382 ? 283 GLY D HA2  1 c 
ATOM   5413 H HA3  . GLY B 1 115 ? 4.963   51.625  -20.015 0.33  33.382 ? 283 GLY D HA3  1 c 
ATOM   5414 N N    . PRO B 1 116 ? 3.882   50.078  -17.947 0.33  32.23  ? 284 PRO D N    1 ? 
ATOM   5415 C CA   . PRO B 1 116 ? 3.872   49.001  -16.952 0.33  31.185 ? 284 PRO D CA   1 ? 
ATOM   5416 C C    . PRO B 1 116 ? 5.014   48.011  -17.134 0.33  31.188 ? 284 PRO D C    1 ? 
ATOM   5417 O O    . PRO B 1 116 ? 5.327   47.61   -18.253 0.33  29.437 ? 284 PRO D O    1 ? 
ATOM   5418 C CB   . PRO B 1 116 ? 2.493   48.326  -17.178 0.33  31.665 ? 284 PRO D CB   1 ? 
ATOM   5419 C CG   . PRO B 1 116 ? 2.13    48.675  -18.609 0.33  29.924 ? 284 PRO D CG   1 ? 
ATOM   5420 C CD   . PRO B 1 116 ? 2.684   50.072  -18.81  0.33  31.443 ? 284 PRO D CD   1 ? 
ATOM   5421 H HA   . PRO B 1 116 ? 3.906   49.395  -16.044 0.33  31.471 ? 284 PRO D HA   1 c 
ATOM   5422 H HB2  . PRO B 1 116 ? 2.556   47.349  -17.06  0.33  31.157 ? 284 PRO D HB2  1 c 
ATOM   5423 H HB3  . PRO B 1 116 ? 1.821   48.68   -16.549 0.33  31.157 ? 284 PRO D HB3  1 c 
ATOM   5424 H HG2  . PRO B 1 116 ? 2.54    48.044  -19.237 0.33  30.649 ? 284 PRO D HG2  1 c 
ATOM   5425 H HG3  . PRO B 1 116 ? 1.158   48.663  -18.736 0.33  30.649 ? 284 PRO D HG3  1 c 
ATOM   5426 H HD2  . PRO B 1 116 ? 2.923   50.226  -19.751 0.33  31.275 ? 284 PRO D HD2  1 c 
ATOM   5427 H HD3  . PRO B 1 116 ? 2.036   50.754  -18.524 0.33  31.275 ? 284 PRO D HD3  1 c 
ATOM   5428 N N    . VAL B 1 117 ? 5.591   47.572  -16.014 0.33  31.758 ? 285 VAL D N    1 ? 
ATOM   5429 C CA   . VAL B 1 117 ? 6.733   46.679  -16.052 0.33  31.736 ? 285 VAL D CA   1 ? 
ATOM   5430 C C    . VAL B 1 117 ? 6.268   45.284  -16.466 0.33  32.841 ? 285 VAL D C    1 ? 
ATOM   5431 O O    . VAL B 1 117 ? 5.46    44.664  -15.783 0.33  33.641 ? 285 VAL D O    1 ? 
ATOM   5432 C CB   . VAL B 1 117 ? 7.47    46.642  -14.703 0.33  29.519 ? 285 VAL D CB   1 ? 
ATOM   5433 C CG1  . VAL B 1 117 ? 8.491   45.513  -14.655 0.33  30.552 ? 285 VAL D CG1  1 ? 
ATOM   5434 C CG2  . VAL B 1 117 ? 8.126   47.98   -14.392 0.33  29.648 ? 285 VAL D CG2  1 ? 
ATOM   5435 H H    . VAL B 1 117 ? 5.263   47.837  -15.203 0.33  31.616 ? 285 VAL D H    1 c 
ATOM   5436 H HA   . VAL B 1 117 ? 7.354   47.009  -16.731 0.33  31.521 ? 285 VAL D HA   1 c 
ATOM   5437 H HB   . VAL B 1 117 ? 6.794   46.468  -14.006 0.33  30.135 ? 285 VAL D HB   1 c 
ATOM   5438 H HG11 . VAL B 1 117 ? 9.152   45.642  -15.357 0.33  30.244 ? 285 VAL D HG11 1 c 
ATOM   5439 H HG12 . VAL B 1 117 ? 8.041   44.662  -14.788 0.33  30.244 ? 285 VAL D HG12 1 c 
ATOM   5440 H HG13 . VAL B 1 117 ? 8.935   45.512  -13.79  0.33  30.244 ? 285 VAL D HG13 1 c 
ATOM   5441 H HG21 . VAL B 1 117 ? 8.58    47.928  -13.534 0.33  29.61  ? 285 VAL D HG21 1 c 
ATOM   5442 H HG22 . VAL B 1 117 ? 7.447   48.674  -14.356 0.33  29.61  ? 285 VAL D HG22 1 c 
ATOM   5443 H HG23 . VAL B 1 117 ? 8.771   48.194  -15.086 0.33  29.61  ? 285 VAL D HG23 1 c 
ATOM   5444 N N    . SER B 1 118 ? 6.799   44.79   -17.586 0.33  34.356 ? 286 SER D N    1 ? 
ATOM   5445 C CA   . SER B 1 118 ? 6.484   43.445  -18.04  0.33  35.452 ? 286 SER D CA   1 ? 
ATOM   5446 C C    . SER B 1 118 ? 6.595   42.462  -16.874 0.33  34.626 ? 286 SER D C    1 ? 
ATOM   5447 O O    . SER B 1 118 ? 7.653   42.333  -16.261 0.33  30.79  ? 286 SER D O    1 ? 
ATOM   5448 C CB   . SER B 1 118 ? 7.38    43.041  -19.182 0.33  36.603 ? 286 SER D CB   1 ? 
ATOM   5449 H H    . SER B 1 118 ? 7.372   45.303  -18.08  0.33  34.229 ? 286 SER D H    1 c 
ATOM   5450 H HA   . SER B 1 118 ? 5.546   43.44   -18.36  0.33  35.293 ? 286 SER D HA   1 c 
ATOM   5451 N N    . GLY B 1 119 ? 5.497   41.76   -16.576 0.33  37.959 ? 287 GLY D N    1 ? 
ATOM   5452 C CA   . GLY B 1 119 ? 5.499   40.768  -15.51  0.33  40.003 ? 287 GLY D CA   1 ? 
ATOM   5453 C C    . GLY B 1 119 ? 5.028   41.349  -14.178 0.33  42.316 ? 287 GLY D C    1 ? 
ATOM   5454 O O    . GLY B 1 119 ? 4.423   40.641  -13.377 0.33  42.708 ? 287 GLY D O    1 ? 
ATOM   5455 H H    . GLY B 1 119 ? 4.728   41.902  -17.049 0.33  37.575 ? 287 GLY D H    1 c 
ATOM   5456 H HA2  . GLY B 1 119 ? 4.91    40.02   -15.768 0.33  40.004 ? 287 GLY D HA2  1 c 
ATOM   5457 H HA3  . GLY B 1 119 ? 6.412   40.411  -15.407 0.33  40.004 ? 287 GLY D HA3  1 c 
ATOM   5458 N N    . TRP B 1 120 ? 5.301   42.642  -13.942 0.33  43.752 ? 288 TRP D N    1 ? 
ATOM   5459 C CA   . TRP B 1 120 ? 4.916   43.293  -12.698 0.33  45.595 ? 288 TRP D CA   1 ? 
ATOM   5460 C C    . TRP B 1 120 ? 4.081   44.545  -12.985 0.33  46.549 ? 288 TRP D C    1 ? 
ATOM   5461 O O    . TRP B 1 120 ? 4.584   45.661  -12.884 0.33  44.96  ? 288 TRP D O    1 ? 
ATOM   5462 C CB   . TRP B 1 120 ? 6.166   43.641  -11.874 0.33  45.612 ? 288 TRP D CB   1 ? 
ATOM   5463 C CG   . TRP B 1 120 ? 6.84    42.461  -11.222 0.33  46.292 ? 288 TRP D CG   1 ? 
ATOM   5464 C CD1  . TRP B 1 120 ? 6.464   41.842  -10.066 0.33  47.739 ? 288 TRP D CD1  1 ? 
ATOM   5465 C CD2  . TRP B 1 120 ? 8.029   41.773  -11.673 0.33  49.366 ? 288 TRP D CD2  1 ? 
ATOM   5466 N NE1  . TRP B 1 120 ? 7.319   40.813  -9.772  0.33  47.087 ? 288 TRP D NE1  1 ? 
ATOM   5467 C CE2  . TRP B 1 120 ? 8.29    40.747  -10.738 0.33  48.075 ? 288 TRP D CE2  1 ? 
ATOM   5468 C CE3  . TRP B 1 120 ? 8.889   41.922  -12.767 0.33  49.413 ? 288 TRP D CE3  1 ? 
ATOM   5469 C CZ2  . TRP B 1 120 ? 9.372   39.879  -10.87  0.33  49.805 ? 288 TRP D CZ2  1 ? 
ATOM   5470 C CZ3  . TRP B 1 120 ? 9.961   41.066  -12.893 0.33  51.257 ? 288 TRP D CZ3  1 ? 
ATOM   5471 C CH2  . TRP B 1 120 ? 10.198  40.057  -11.957 0.33  51.057 ? 288 TRP D CH2  1 ? 
ATOM   5472 H H    . TRP B 1 120 ? 5.74    43.13   -14.578 0.33  43.81  ? 288 TRP D H    1 c 
ATOM   5473 H HA   . TRP B 1 120 ? 4.362   42.656  -12.171 0.33  45.403 ? 288 TRP D HA   1 c 
ATOM   5474 H HB2  . TRP B 1 120 ? 6.811   44.087  -12.463 0.33  45.764 ? 288 TRP D HB2  1 c 
ATOM   5475 H HB3  . TRP B 1 120 ? 5.909   44.282  -11.177 0.33  45.764 ? 288 TRP D HB3  1 c 
ATOM   5476 H HD1  . TRP B 1 120 ? 5.714   42.077  -9.544  0.33  47.271 ? 288 TRP D HD1  1 c 
ATOM   5477 H HE1  . TRP B 1 120 ? 7.254   40.286  -9.079  0.33  47.484 ? 288 TRP D HE1  1 c 
ATOM   5478 H HE3  . TRP B 1 120 ? 8.737   42.598  -13.405 0.33  49.807 ? 288 TRP D HE3  1 c 
ATOM   5479 H HZ2  . TRP B 1 120 ? 9.535   39.201  -10.236 0.33  49.682 ? 288 TRP D HZ2  1 c 
ATOM   5480 H HZ3  . TRP B 1 120 ? 10.544  41.158  -13.629 0.33  50.729 ? 288 TRP D HZ3  1 c 
ATOM   5481 H HH2  . TRP B 1 120 ? 10.937  39.487  -12.071 0.33  50.757 ? 288 TRP D HH2  1 c 
ATOM   5482 N N    . PRO B 1 121 ? 2.779   44.42   -13.34  0.33  48.051 ? 289 PRO D N    1 ? 
ATOM   5483 C CA   . PRO B 1 121 ? 1.976   45.581  -13.739 0.33  48.779 ? 289 PRO D CA   1 ? 
ATOM   5484 C C    . PRO B 1 121 ? 1.694   46.622  -12.654 0.33  49.124 ? 289 PRO D C    1 ? 
ATOM   5485 O O    . PRO B 1 121 ? 1.083   47.651  -12.939 0.33  52.119 ? 289 PRO D O    1 ? 
ATOM   5486 C CB   . PRO B 1 121 ? 0.676   44.94   -14.263 0.33  49.23  ? 289 PRO D CB   1 ? 
ATOM   5487 C CG   . PRO B 1 121 ? 0.593   43.62   -13.535 0.33  49.405 ? 289 PRO D CG   1 ? 
ATOM   5488 C CD   . PRO B 1 121 ? 2.031   43.153  -13.43  0.33  49.53  ? 289 PRO D CD   1 ? 
ATOM   5489 H HA   . PRO B 1 121 ? 2.44    46.022  -14.494 0.33  48.779 ? 289 PRO D HA   1 c 
ATOM   5490 H HB2  . PRO B 1 121 ? -0.104  45.507  -14.055 0.33  49.169 ? 289 PRO D HB2  1 c 
ATOM   5491 H HB3  . PRO B 1 121 ? 0.72    44.802  -15.238 0.33  49.169 ? 289 PRO D HB3  1 c 
ATOM   5492 H HG2  . PRO B 1 121 ? 0.2     43.736  -12.645 0.33  49.393 ? 289 PRO D HG2  1 c 
ATOM   5493 H HG3  . PRO B 1 121 ? 0.054   42.976  -14.039 0.33  49.393 ? 289 PRO D HG3  1 c 
ATOM   5494 H HD2  . PRO B 1 121 ? 2.167   42.602  -12.628 0.33  49.156 ? 289 PRO D HD2  1 c 
ATOM   5495 H HD3  . PRO B 1 121 ? 2.295   42.639  -14.226 0.33  49.156 ? 289 PRO D HD3  1 c 
ATOM   5496 N N    . ASP B 1 122 ? 2.148   46.356  -11.423 0.33  45.907 ? 290 ASP D N    1 ? 
ATOM   5497 C CA   . ASP B 1 122 ? 2.003   47.296  -10.321 0.33  43.331 ? 290 ASP D CA   1 ? 
ATOM   5498 C C    . ASP B 1 122 ? 3.108   48.352  -10.354 0.33  40.382 ? 290 ASP D C    1 ? 
ATOM   5499 O O    . ASP B 1 122 ? 3.164   49.197  -9.462  0.33  42.905 ? 290 ASP D O    1 ? 
ATOM   5500 C CB   . ASP B 1 122 ? 2.043   46.593  -8.972  0.33  41.941 ? 290 ASP D CB   1 ? 
ATOM   5501 H H    . ASP B 1 122 ? 2.564   45.557  -11.266 0.33  46.051 ? 290 ASP D H    1 c 
ATOM   5502 H HA   . ASP B 1 122 ? 1.132   47.746  -10.411 0.33  43.002 ? 290 ASP D HA   1 c 
ATOM   5503 N N    . GLU B 1 123 ? 3.984   48.287  -11.366 0.33  35.691 ? 291 GLU D N    1 ? 
ATOM   5504 C CA   . GLU B 1 123 ? 5.119   49.192  -11.465 0.33  32.822 ? 291 GLU D CA   1 ? 
ATOM   5505 C C    . GLU B 1 123 ? 5.171   49.873  -12.837 0.33  28.959 ? 291 GLU D C    1 ? 
ATOM   5506 O O    . GLU B 1 123 ? 4.71    49.339  -13.846 0.33  28.117 ? 291 GLU D O    1 ? 
ATOM   5507 C CB   . GLU B 1 123 ? 6.427   48.433  -11.246 0.33  32.55  ? 291 GLU D CB   1 ? 
ATOM   5508 C CG   . GLU B 1 123 ? 6.456   47.542  -10.009 0.33  34.513 ? 291 GLU D CG   1 ? 
ATOM   5509 C CD   . GLU B 1 123 ? 7.736   46.736  -9.848  0.33  33.574 ? 291 GLU D CD   1 ? 
ATOM   5510 O OE1  . GLU B 1 123 ? 8.687   46.904  -10.643 0.33  33.736 ? 291 GLU D OE1  1 ? 
ATOM   5511 O OE2  . GLU B 1 123 ? 7.769   45.897  -8.926  0.33  33.071 ? 291 GLU D OE2  1 ? 
ATOM   5512 H H    . GLU B 1 123 ? 3.868   47.655  -12.016 0.33  36.07  ? 291 GLU D H    1 c 
ATOM   5513 H HA   . GLU B 1 123 ? 5.026   49.888  -10.766 0.33  32.563 ? 291 GLU D HA   1 c 
ATOM   5514 H HB2  . GLU B 1 123 ? 6.6     47.876  -12.033 0.33  33.051 ? 291 GLU D HB2  1 c 
ATOM   5515 H HB3  . GLU B 1 123 ? 7.157   49.083  -11.176 0.33  33.051 ? 291 GLU D HB3  1 c 
ATOM   5516 H HG2  . GLU B 1 123 ? 6.337   48.1    -9.211  0.33  33.842 ? 291 GLU D HG2  1 c 
ATOM   5517 H HG3  . GLU B 1 123 ? 5.699   46.918  -10.048 0.33  33.842 ? 291 GLU D HG3  1 c 
ATOM   5518 N N    . GLN B 1 124 ? 5.815   51.043  -12.866 0.33  25.504 ? 292 GLN D N    1 ? 
ATOM   5519 C CA   . GLN B 1 124 ? 6.149   51.72   -14.106 0.33  24.765 ? 292 GLN D CA   1 ? 
ATOM   5520 C C    . GLN B 1 124 ? 7.663   51.801  -14.28  0.33  23.674 ? 292 GLN D C    1 ? 
ATOM   5521 O O    . GLN B 1 124 ? 8.386   52.135  -13.34  0.33  23.687 ? 292 GLN D O    1 ? 
ATOM   5522 C CB   . GLN B 1 124 ? 5.623   53.148  -14.068 0.33  25.628 ? 292 GLN D CB   1 ? 
ATOM   5523 C CG   . GLN B 1 124 ? 4.106   53.285  -14.054 0.33  26.341 ? 292 GLN D CG   1 ? 
ATOM   5524 C CD   . GLN B 1 124 ? 3.492   53.155  -15.426 0.33  26.135 ? 292 GLN D CD   1 ? 
ATOM   5525 O OE1  . GLN B 1 124 ? 4.079   53.562  -16.434 0.33  27.141 ? 292 GLN D OE1  1 ? 
ATOM   5526 N NE2  . GLN B 1 124 ? 2.314   52.553  -15.479 0.33  29.758 ? 292 GLN D NE2  1 ? 
ATOM   5527 H H    . GLN B 1 124 ? 6.056   51.434  -12.076 0.33  26.114 ? 292 GLN D H    1 c 
ATOM   5528 H HA   . GLN B 1 124 ? 5.751   51.222  -14.865 0.33  24.857 ? 292 GLN D HA   1 c 
ATOM   5529 H HB2  . GLN B 1 124 ? 5.984   53.588  -13.271 0.33  25.587 ? 292 GLN D HB2  1 c 
ATOM   5530 H HB3  . GLN B 1 124 ? 5.972   53.625  -14.85  0.33  25.587 ? 292 GLN D HB3  1 c 
ATOM   5531 H HG2  . GLN B 1 124 ? 3.725   52.595  -13.47  0.33  26.131 ? 292 GLN D HG2  1 c 
ATOM   5532 H HG3  . GLN B 1 124 ? 3.864   54.159  -13.68  0.33  26.131 ? 292 GLN D HG3  1 c 
ATOM   5533 H HE21 . GLN B 1 124 ? 1.903   52.451  -16.258 0.33  28.592 ? 292 GLN D HE21 1 c 
ATOM   5534 H HE22 . GLN B 1 124 ? 1.937   52.253  -14.734 0.33  28.592 ? 292 GLN D HE22 1 c 
ATOM   5535 N N    . TYR B 1 125 ? 8.125   51.481  -15.49  0.33  23.258 ? 293 TYR D N    1 ? 
ATOM   5536 C CA   . TYR B 1 125 ? 9.451   51.87   -15.921 0.33  23.141 ? 293 TYR D CA   1 ? 
ATOM   5537 C C    . TYR B 1 125 ? 9.548   53.391  -15.851 0.33  23.305 ? 293 TYR D C    1 ? 
ATOM   5538 O O    . TYR B 1 125 ? 8.55    54.084  -16.039 0.33  24.544 ? 293 TYR D O    1 ? 
ATOM   5539 C CB   . TYR B 1 125 ? 9.73    51.452  -17.363 0.33  23.308 ? 293 TYR D CB   1 ? 
ATOM   5540 C CG   . TYR B 1 125 ? 9.7     49.961  -17.655 0.33  21.435 ? 293 TYR D CG   1 ? 
ATOM   5541 C CD1  . TYR B 1 125 ? 10.665  49.117  -17.142 0.33  20.557 ? 293 TYR D CD1  1 ? 
ATOM   5542 C CD2  . TYR B 1 125 ? 8.75    49.414  -18.507 0.33  21.408 ? 293 TYR D CD2  1 ? 
ATOM   5543 C CE1  . TYR B 1 125 ? 10.668  47.759  -17.421 0.33  20.46  ? 293 TYR D CE1  1 ? 
ATOM   5544 C CE2  . TYR B 1 125 ? 8.75    48.06   -18.814 0.33  21.41  ? 293 TYR D CE2  1 ? 
ATOM   5545 C CZ   . TYR B 1 125 ? 9.714   47.227  -18.273 0.33  21.281 ? 293 TYR D CZ   1 ? 
ATOM   5546 O OH   . TYR B 1 125 ? 9.702   45.881  -18.554 0.33  22.524 ? 293 TYR D OH   1 ? 
ATOM   5547 H H    . TYR B 1 125 ? 7.595   51.005  -16.063 0.33  23.33  ? 293 TYR D H    1 c 
ATOM   5548 H HA   . TYR B 1 125 ? 10.129  51.464  -15.318 0.33  23.224 ? 293 TYR D HA   1 c 
ATOM   5549 H HB2  . TYR B 1 125 ? 9.071   51.896  -17.942 0.33  22.828 ? 293 TYR D HB2  1 c 
ATOM   5550 H HB3  . TYR B 1 125 ? 10.615  51.8    -17.615 0.33  22.828 ? 293 TYR D HB3  1 c 
ATOM   5551 H HD1  . TYR B 1 125 ? 11.325  49.469  -16.566 0.33  20.763 ? 293 TYR D HD1  1 c 
ATOM   5552 H HD2  . TYR B 1 125 ? 8.094   49.974  -18.891 0.33  21.417 ? 293 TYR D HD2  1 c 
ATOM   5553 H HE1  . TYR B 1 125 ? 11.33   47.201  -17.048 0.33  20.699 ? 293 TYR D HE1  1 c 
ATOM   5554 H HE2  . TYR B 1 125 ? 8.087   47.705  -19.381 0.33  21.381 ? 293 TYR D HE2  1 c 
ATOM   5555 N N    . VAL B 1 126 ? 10.756  53.9    -15.59  0.33  21.927 ? 294 VAL D N    1 ? 
ATOM   5556 C CA   . VAL B 1 126 ? 10.983  55.333  -15.559 0.33  21.06  ? 294 VAL D CA   1 ? 
ATOM   5557 C C    . VAL B 1 126 ? 12.158  55.692  -16.461 0.33  20.343 ? 294 VAL D C    1 ? 
ATOM   5558 O O    . VAL B 1 126 ? 13      54.862  -16.794 0.33  21.539 ? 294 VAL D O    1 ? 
ATOM   5559 C CB   . VAL B 1 126 ? 11.206  55.854  -14.125 0.33  21.244 ? 294 VAL D CB   1 ? 
ATOM   5560 C CG1  . VAL B 1 126 ? 9.996   55.592  -13.235 0.33  20.905 ? 294 VAL D CG1  1 ? 
ATOM   5561 C CG2  . VAL B 1 126 ? 12.472  55.302  -13.478 0.33  22.567 ? 294 VAL D CG2  1 ? 
ATOM   5562 H H    . VAL B 1 126 ? 11.457  53.337  -15.428 0.33  22.046 ? 294 VAL D H    1 c 
ATOM   5563 H HA   . VAL B 1 126 ? 10.185  55.768  -15.916 0.33  21.123 ? 294 VAL D HA   1 c 
ATOM   5564 H HB   . VAL B 1 126 ? 11.314  56.832  -14.19  0.33  21.386 ? 294 VAL D HB   1 c 
ATOM   5565 H HG11 . VAL B 1 126 ? 9.827   54.636  -13.19  0.33  21.004 ? 294 VAL D HG11 1 c 
ATOM   5566 H HG12 . VAL B 1 126 ? 9.217   56.04   -13.606 0.33  21.004 ? 294 VAL D HG12 1 c 
ATOM   5567 H HG13 . VAL B 1 126 ? 10.17   55.933  -12.342 0.33  21.004 ? 294 VAL D HG13 1 c 
ATOM   5568 H HG21 . VAL B 1 126 ? 12.566  55.667  -12.582 0.33  22.17  ? 294 VAL D HG21 1 c 
ATOM   5569 H HG22 . VAL B 1 126 ? 13.245  55.553  -14.011 0.33  22.17  ? 294 VAL D HG22 1 c 
ATOM   5570 H HG23 . VAL B 1 126 ? 12.416  54.333  -13.428 0.33  22.17  ? 294 VAL D HG23 1 c 
ATOM   5571 N N    . LYS B 1 127 ? 12.188  56.967  -16.857 0.33  19.956 ? 295 LYS D N    1 ? 
ATOM   5572 C CA   . LYS B 1 127 ? 13.322  57.553  -17.548 0.33  21.634 ? 295 LYS D CA   1 ? 
ATOM   5573 C C    . LYS B 1 127 ? 14.43   57.751  -16.519 0.33  22.597 ? 295 LYS D C    1 ? 
ATOM   5574 O O    . LYS B 1 127 ? 14.588  58.832  -15.957 0.33  23.793 ? 295 LYS D O    1 ? 
ATOM   5575 C CB   . LYS B 1 127 ? 12.908  58.877  -18.2   0.33  23.121 ? 295 LYS D CB   1 ? 
ATOM   5576 C CG   . LYS B 1 127 ? 11.799  58.727  -19.245 0.33  24.657 ? 295 LYS D CG   1 ? 
ATOM   5577 C CD   . LYS B 1 127 ? 11.414  59.93   -20.094 0.33  28.123 ? 295 LYS D CD   1 ? 
ATOM   5578 C CE   . LYS B 1 127 ? 11.569  61.258  -19.431 0.33  30.875 ? 295 LYS D CE   1 ? 
ATOM   5579 N NZ   . LYS B 1 127 ? 12.839  61.881  -19.814 0.33  32.326 ? 295 LYS D NZ   1 ? 
ATOM   5580 H H    . LYS B 1 127 ? 11.463  57.496  -16.686 0.33  20.417 ? 295 LYS D H    1 c 
ATOM   5581 H HA   . LYS B 1 127 ? 13.633  56.919  -18.243 0.33  21.723 ? 295 LYS D HA   1 c 
ATOM   5582 H HB2  . LYS B 1 127 ? 12.6    59.493  -17.502 0.33  23.112 ? 295 LYS D HB2  1 c 
ATOM   5583 H HB3  . LYS B 1 127 ? 13.692  59.279  -18.631 0.33  23.112 ? 295 LYS D HB3  1 c 
ATOM   5584 H HG2  . LYS B 1 127 ? 12.062  58.001  -19.852 0.33  25.043 ? 295 LYS D HG2  1 c 
ATOM   5585 H HG3  . LYS B 1 127 ? 10.993  58.418  -18.777 0.33  25.043 ? 295 LYS D HG3  1 c 
ATOM   5586 H HD2  . LYS B 1 127 ? 11.962  59.921  -20.909 0.33  27.893 ? 295 LYS D HD2  1 c 
ATOM   5587 H HD3  . LYS B 1 127 ? 10.478  59.826  -20.372 0.33  27.893 ? 295 LYS D HD3  1 c 
ATOM   5588 H HE2  . LYS B 1 127 ? 10.835  61.843  -19.692 0.33  30.551 ? 295 LYS D HE2  1 c 
ATOM   5589 H HE3  . LYS B 1 127 ? 11.546  61.148  -18.464 0.33  30.551 ? 295 LYS D HE3  1 c 
ATOM   5590 H HZ1  . LYS B 1 127 ? 12.85   62.031  -20.708 0.33  31.872 ? 295 LYS D HZ1  1 c 
ATOM   5591 H HZ2  . LYS B 1 127 ? 13.527  61.334  -19.595 0.33  31.872 ? 295 LYS D HZ2  1 c 
ATOM   5592 H HZ3  . LYS B 1 127 ? 12.937  62.67   -19.379 0.33  31.872 ? 295 LYS D HZ3  1 c 
ATOM   5593 N N    . TYR B 1 128 ? 15.197  56.688  -16.277 0.33  22.673 ? 296 TYR D N    1 ? 
ATOM   5594 C CA   . TYR B 1 128 ? 16.111  56.634  -15.143 0.33  22.414 ? 296 TYR D CA   1 ? 
ATOM   5595 C C    . TYR B 1 128 ? 17.308  57.566  -15.351 0.33  22.139 ? 296 TYR D C    1 ? 
ATOM   5596 O O    . TYR B 1 128 ? 18.075  57.79   -14.419 0.33  21.255 ? 296 TYR D O    1 ? 
ATOM   5597 C CB   . TYR B 1 128 ? 16.573  55.181  -14.969 0.33  20.922 ? 296 TYR D CB   1 ? 
ATOM   5598 C CG   . TYR B 1 128 ? 17.139  54.579  -16.249 0.33  19.185 ? 296 TYR D CG   1 ? 
ATOM   5599 C CD1  . TYR B 1 128 ? 18.457  54.821  -16.631 0.33  18.538 ? 296 TYR D CD1  1 ? 
ATOM   5600 C CD2  . TYR B 1 128 ? 16.342  53.823  -17.108 0.33  19.339 ? 296 TYR D CD2  1 ? 
ATOM   5601 C CE1  . TYR B 1 128 ? 18.975  54.312  -17.814 0.33  18.352 ? 296 TYR D CE1  1 ? 
ATOM   5602 C CE2  . TYR B 1 128 ? 16.843  53.313  -18.294 0.33  18.672 ? 296 TYR D CE2  1 ? 
ATOM   5603 C CZ   . TYR B 1 128 ? 18.156  53.564  -18.651 0.33  18.321 ? 296 TYR D CZ   1 ? 
ATOM   5604 O OH   . TYR B 1 128 ? 18.625  53.041  -19.817 0.33  19.676 ? 296 TYR D OH   1 ? 
ATOM   5605 H H    . TYR B 1 128 ? 15.149  55.968  -16.838 0.33  22.596 ? 296 TYR D H    1 c 
ATOM   5606 H HA   . TYR B 1 128 ? 15.622  56.915  -14.325 0.33  22.135 ? 296 TYR D HA   1 c 
ATOM   5607 H HB2  . TYR B 1 128 ? 17.262  55.151  -14.268 0.33  20.836 ? 296 TYR D HB2  1 c 
ATOM   5608 H HB3  . TYR B 1 128 ? 15.808  54.641  -14.671 0.33  20.836 ? 296 TYR D HB3  1 c 
ATOM   5609 H HD1  . TYR B 1 128 ? 19.012  55.341  -16.072 0.33  18.658 ? 296 TYR D HD1  1 c 
ATOM   5610 H HD2  . TYR B 1 128 ? 15.441  53.66   -16.88  0.33  19.143 ? 296 TYR D HD2  1 c 
ATOM   5611 H HE1  . TYR B 1 128 ? 19.87   54.48   -18.054 0.33  18.412 ? 296 TYR D HE1  1 c 
ATOM   5612 H HE2  . TYR B 1 128 ? 16.291  52.799  -18.859 0.33  18.753 ? 296 TYR D HE2  1 c 
ATOM   5613 N N    . TRP B 1 129 ? 17.476  58.075  -16.58  0.33  23.071 ? 297 TRP D N    1 ? 
ATOM   5614 C CA   . TRP B 1 129 ? 18.585  58.957  -16.914 0.33  23.872 ? 297 TRP D CA   1 ? 
ATOM   5615 C C    . TRP B 1 129 ? 18.176  60.412  -16.716 0.33  23.873 ? 297 TRP D C    1 ? 
ATOM   5616 O O    . TRP B 1 129 ? 19.004  61.31   -16.824 0.33  23.466 ? 297 TRP D O    1 ? 
ATOM   5617 C CB   . TRP B 1 129 ? 19.013  58.733  -18.368 0.33  24.983 ? 297 TRP D CB   1 ? 
ATOM   5618 C CG   . TRP B 1 129 ? 17.903  59.075  -19.325 0.33  25.603 ? 297 TRP D CG   1 ? 
ATOM   5619 C CD1  . TRP B 1 129 ? 17.595  60.311  -19.817 0.33  27.499 ? 297 TRP D CD1  1 ? 
ATOM   5620 C CD2  . TRP B 1 129 ? 16.905  58.175  -19.847 0.33  25.863 ? 297 TRP D CD2  1 ? 
ATOM   5621 N NE1  . TRP B 1 129 ? 16.486  60.242  -20.616 0.33  26.701 ? 297 TRP D NE1  1 ? 
ATOM   5622 C CE2  . TRP B 1 129 ? 16.038  58.948  -20.65  0.33  26.347 ? 297 TRP D CE2  1 ? 
ATOM   5623 C CE3  . TRP B 1 129 ? 16.658  56.807  -19.711 0.33  26.765 ? 297 TRP D CE3  1 ? 
ATOM   5624 C CZ2  . TRP B 1 129 ? 14.95   58.391  -21.316 0.33  27.181 ? 297 TRP D CZ2  1 ? 
ATOM   5625 C CZ3  . TRP B 1 129 ? 15.589  56.255  -20.387 0.33  27.333 ? 297 TRP D CZ3  1 ? 
ATOM   5626 C CH2  . TRP B 1 129 ? 14.748  57.037  -21.177 0.33  26.464 ? 297 TRP D CH2  1 ? 
ATOM   5627 H H    . TRP B 1 129 ? 16.874  57.863  -17.234 0.33  23.022 ? 297 TRP D H    1 c 
ATOM   5628 H HA   . TRP B 1 129 ? 19.352  58.749  -16.317 0.33  23.911 ? 297 TRP D HA   1 c 
ATOM   5629 H HB2  . TRP B 1 129 ? 19.791  59.298  -18.56  0.33  24.868 ? 297 TRP D HB2  1 c 
ATOM   5630 H HB3  . TRP B 1 129 ? 19.261  57.791  -18.484 0.33  24.868 ? 297 TRP D HB3  1 c 
ATOM   5631 H HD1  . TRP B 1 129 ? 18.073  61.105  -19.638 0.33  26.856 ? 297 TRP D HD1  1 c 
ATOM   5632 H HE1  . TRP B 1 129 ? 16.126  60.915  -21.039 0.33  26.791 ? 297 TRP D HE1  1 c 
ATOM   5633 H HE3  . TRP B 1 129 ? 17.226  56.268  -19.187 0.33  26.682 ? 297 TRP D HE3  1 c 
ATOM   5634 H HZ2  . TRP B 1 129 ? 14.385  58.919  -21.854 0.33  26.816 ? 297 TRP D HZ2  1 c 
ATOM   5635 H HZ3  . TRP B 1 129 ? 15.415  55.333  -20.302 0.33  26.983 ? 297 TRP D HZ3  1 c 
ATOM   5636 H HH2  . TRP B 1 129 ? 14.018  56.634  -21.613 0.33  26.823 ? 297 TRP D HH2  1 c 
ATOM   5637 N N    . ASP B 1 130 ? 16.886  60.633  -16.462 0.33  22.931 ? 298 ASP D N    1 ? 
ATOM   5638 C CA   . ASP B 1 130 ? 16.355  61.971  -16.315 0.33  22.56  ? 298 ASP D CA   1 ? 
ATOM   5639 C C    . ASP B 1 130 ? 16.77   62.508  -14.951 0.33  21.703 ? 298 ASP D C    1 ? 
ATOM   5640 O O    . ASP B 1 130 ? 16.708  61.811  -13.945 0.33  20.379 ? 298 ASP D O    1 ? 
ATOM   5641 C CB   . ASP B 1 130 ? 14.843  61.962  -16.417 0.33  24.353 ? 298 ASP D CB   1 ? 
ATOM   5642 C CG   . ASP B 1 130 ? 14.195  63.325  -16.552 0.33  23.899 ? 298 ASP D CG   1 ? 
ATOM   5643 O OD1  . ASP B 1 130 ? 14.232  64.106  -15.582 0.33  24.597 ? 298 ASP D OD1  1 ? 
ATOM   5644 O OD2  . ASP B 1 130 ? 13.642  63.58   -17.633 0.33  25.876 ? 298 ASP D OD2  1 ? 
ATOM   5645 H H    . ASP B 1 130 ? 16.318  59.922  -16.379 0.33  23.067 ? 298 ASP D H    1 c 
ATOM   5646 H HA   . ASP B 1 130 ? 16.734  62.543  -17.02  0.33  22.789 ? 298 ASP D HA   1 c 
ATOM   5647 H HB2  . ASP B 1 130 ? 14.586  61.424  -17.195 0.33  23.827 ? 298 ASP D HB2  1 c 
ATOM   5648 H HB3  . ASP B 1 130 ? 14.478  61.529  -15.618 0.33  23.827 ? 298 ASP D HB3  1 c 
ATOM   5649 N N    A GLU B 1 131 ? 17.154  63.786  -14.93  0.17  20.805 ? 299 GLU D N    1 ? 
ATOM   5650 N N    B GLU B 1 131 ? 17.212  63.758  -14.911 0.17  20.417 ? 299 GLU D N    1 ? 
ATOM   5651 C CA   A GLU B 1 131 ? 17.675  64.396  -13.725 0.17  19.821 ? 299 GLU D CA   1 ? 
ATOM   5652 C CA   B GLU B 1 131 ? 17.681  64.291  -13.652 0.17  19.286 ? 299 GLU D CA   1 ? 
ATOM   5653 C C    A GLU B 1 131 ? 16.604  64.408  -12.638 0.17  19.883 ? 299 GLU D C    1 ? 
ATOM   5654 C C    B GLU B 1 131 ? 16.571  64.217  -12.606 0.17  19.584 ? 299 GLU D C    1 ? 
ATOM   5655 O O    A GLU B 1 131 ? 16.948  64.375  -11.459 0.17  20.588 ? 299 GLU D O    1 ? 
ATOM   5656 O O    B GLU B 1 131 ? 16.83   63.958  -11.433 0.17  19.418 ? 299 GLU D O    1 ? 
ATOM   5657 C CB   A GLU B 1 131 ? 18.256  65.77   -14.06  0.17  18.565 ? 299 GLU D CB   1 ? 
ATOM   5658 C CB   B GLU B 1 131 ? 18.22   65.709  -13.784 0.17  17.795 ? 299 GLU D CB   1 ? 
ATOM   5659 C CG   A GLU B 1 131 ? 19.546  65.704  -14.875 0.17  17.761 ? 299 GLU D CG   1 ? 
ATOM   5660 C CG   B GLU B 1 131 ? 18.715  66.185  -12.428 0.17  16.745 ? 299 GLU D CG   1 ? 
ATOM   5661 C CD   A GLU B 1 131 ? 20.793  65.267  -14.12  0.17  16.867 ? 299 GLU D CD   1 ? 
ATOM   5662 C CD   B GLU B 1 131 ? 20.011  65.528  -11.969 0.17  15.28  ? 299 GLU D CD   1 ? 
ATOM   5663 O OE1  A GLU B 1 131 ? 20.704  64.854  -12.942 0.17  18.025 ? 299 GLU D OE1  1 ? 
ATOM   5664 O OE1  B GLU B 1 131 ? 20.536  64.696  -12.728 0.17  16.451 ? 299 GLU D OE1  1 ? 
ATOM   5665 O OE2  A GLU B 1 131 ? 21.883  65.369  -14.712 0.17  15.68  ? 299 GLU D OE2  1 ? 
ATOM   5666 O OE2  B GLU B 1 131 ? 20.508  65.86   -10.879 0.17  13.717 ? 299 GLU D OE2  1 ? 
ATOM   5667 H H    A GLU B 1 131 ? 17.089  64.29   -15.69  0.17  20.787 ? 299 GLU D H    1 c 
ATOM   5668 H H    B GLU B 1 131 ? 17.223  64.279  -15.662 0.17  20.453 ? 299 GLU D H    1 c 
ATOM   5669 H HA   A GLU B 1 131 ? 18.424  63.832  -13.403 0.17  19.78  ? 299 GLU D HA   1 c 
ATOM   5670 H HA   B GLU B 1 131 ? 18.428  63.718  -13.343 0.17  19.267 ? 299 GLU D HA   1 c 
ATOM   5671 H HB2  A GLU B 1 131 ? 17.587  66.281  -14.562 0.17  18.655 ? 299 GLU D HB2  1 c 
ATOM   5672 H HB2  B GLU B 1 131 ? 18.951  65.718  -14.437 0.17  17.878 ? 299 GLU D HB2  1 c 
ATOM   5673 H HB3  A GLU B 1 131 ? 18.432  66.251  -13.224 0.17  18.655 ? 299 GLU D HB3  1 c 
ATOM   5674 H HB3  B GLU B 1 131 ? 17.509  66.296  -14.114 0.17  17.878 ? 299 GLU D HB3  1 c 
ATOM   5675 H HG2  A GLU B 1 131 ? 19.411  65.085  -15.625 0.17  17.729 ? 299 GLU D HG2  1 c 
ATOM   5676 H HG2  B GLU B 1 131 ? 18.834  67.154  -12.449 0.17  16.629 ? 299 GLU D HG2  1 c 
ATOM   5677 H HG3  A GLU B 1 131 ? 19.719  66.589  -15.261 0.17  17.729 ? 299 GLU D HG3  1 c 
ATOM   5678 H HG3  B GLU B 1 131 ? 18.021  65.991  -11.769 0.17  16.63  ? 299 GLU D HG3  1 c 
ATOM   5679 N N    . ARG B 1 132 ? 15.319  64.41   -13.024 0.33  20.491 ? 300 ARG D N    1 ? 
ATOM   5680 C CA   . ARG B 1 132 ? 14.227  64.424  -12.061 0.33  20.995 ? 300 ARG D CA   1 ? 
ATOM   5681 C C    . ARG B 1 132 ? 14.12   63.1    -11.297 0.33  19.741 ? 300 ARG D C    1 ? 
ATOM   5682 O O    . ARG B 1 132 ? 13.532  63.061  -10.22  0.33  20.009 ? 300 ARG D O    1 ? 
ATOM   5683 C CB   . ARG B 1 132 ? 12.886  64.773  -12.718 0.33  24.225 ? 300 ARG D CB   1 ? 
ATOM   5684 C CG   . ARG B 1 132 ? 12.746  66.227  -13.142 0.33  27.222 ? 300 ARG D CG   1 ? 
ATOM   5685 C CD   . ARG B 1 132 ? 11.507  66.421  -14.003 0.33  30.055 ? 300 ARG D CD   1 ? 
ATOM   5686 N NE   . ARG B 1 132 ? 11.719  65.839  -15.333 0.33  31.636 ? 300 ARG D NE   1 ? 
ATOM   5687 C CZ   . ARG B 1 132 ? 10.755  65.624  -16.211 0.33  34.823 ? 300 ARG D CZ   1 ? 
ATOM   5688 N NH1  . ARG B 1 132 ? 9.514   65.913  -15.891 0.33  35.272 ? 300 ARG D NH1  1 ? 
ATOM   5689 N NH2  . ARG B 1 132 ? 11.035  65.101  -17.391 0.33  36.009 ? 300 ARG D NH2  1 ? 
ATOM   5690 H H    A ARG B 1 132 ? 15.121  64.401  -13.916 0.056 20.456 ? 300 ARG D H    1 c 
ATOM   5691 H H    B ARG B 1 132 ? 15.141  64.533  -13.912 0.056 20.381 ? 300 ARG D H    1 c 
ATOM   5692 H HA   . ARG B 1 132 ? 14.422  65.137  -11.401 0.33  21.215 ? 300 ARG D HA   1 c 
ATOM   5693 H HB2  . ARG B 1 132 ? 12.768  64.203  -13.508 0.33  24.086 ? 300 ARG D HB2  1 c 
ATOM   5694 H HB3  . ARG B 1 132 ? 12.165  64.56   -12.088 0.33  24.086 ? 300 ARG D HB3  1 c 
ATOM   5695 H HG2  . ARG B 1 132 ? 12.683  66.799  -12.347 0.33  27.115 ? 300 ARG D HG2  1 c 
ATOM   5696 H HG3  . ARG B 1 132 ? 13.537  66.49   -13.658 0.33  27.114 ? 300 ARG D HG3  1 c 
ATOM   5697 H HD2  . ARG B 1 132 ? 10.738  65.99   -13.577 0.33  29.752 ? 300 ARG D HD2  1 c 
ATOM   5698 H HD3  . ARG B 1 132 ? 11.313  67.376  -14.093 0.33  29.752 ? 300 ARG D HD3  1 c 
ATOM   5699 H HE   . ARG B 1 132 ? 12.531  65.62   -15.56  0.33  31.984 ? 300 ARG D HE   1 c 
ATOM   5700 H HH11 . ARG B 1 132 ? 9.334   66.256  -15.096 0.33  35.133 ? 300 ARG D HH11 1 c 
ATOM   5701 H HH12 . ARG B 1 132 ? 8.864   65.763  -16.471 0.33  35.133 ? 300 ARG D HH12 1 c 
ATOM   5702 H HH21 . ARG B 1 132 ? 11.869  64.887  -17.59  0.33  35.64  ? 300 ARG D HH21 1 c 
ATOM   5703 H HH22 . ARG B 1 132 ? 10.387  64.967  -17.977 0.33  35.64  ? 300 ARG D HH22 1 c 
ATOM   5704 N N    . TRP B 1 133 ? 14.694  62.018  -11.83  0.33  18.912 ? 301 TRP D N    1 ? 
ATOM   5705 C CA   . TRP B 1 133 ? 14.662  60.73   -11.153 0.33  16.849 ? 301 TRP D CA   1 ? 
ATOM   5706 C C    . TRP B 1 133 ? 15.761  60.638  -10.091 0.33  16.775 ? 301 TRP D C    1 ? 
ATOM   5707 O O    . TRP B 1 133 ? 15.613  59.937  -9.091  0.33  16.398 ? 301 TRP D O    1 ? 
ATOM   5708 C CB   . TRP B 1 133 ? 14.787  59.619  -12.203 0.33  16.648 ? 301 TRP D CB   1 ? 
ATOM   5709 C CG   . TRP B 1 133 ? 14.889  58.232  -11.639 0.33  15.16  ? 301 TRP D CG   1 ? 
ATOM   5710 C CD1  . TRP B 1 133 ? 15.94   57.37   -11.762 0.33  14.749 ? 301 TRP D CD1  1 ? 
ATOM   5711 C CD2  . TRP B 1 133 ? 13.873  57.527  -10.893 0.33  15.124 ? 301 TRP D CD2  1 ? 
ATOM   5712 N NE1  . TRP B 1 133 ? 15.659  56.201  -11.109 0.33  13.659 ? 301 TRP D NE1  1 ? 
ATOM   5713 C CE2  . TRP B 1 133 ? 14.402  56.259  -10.588 0.33  14.363 ? 301 TRP D CE2  1 ? 
ATOM   5714 C CE3  . TRP B 1 133 ? 12.587  57.84   -10.451 0.33  15.68  ? 301 TRP D CE3  1 ? 
ATOM   5715 C CZ2  . TRP B 1 133 ? 13.686  55.314  -9.864  0.33  14.768 ? 301 TRP D CZ2  1 ? 
ATOM   5716 C CZ3  . TRP B 1 133 ? 11.866  56.896  -9.759  0.33  15.514 ? 301 TRP D CZ3  1 ? 
ATOM   5717 C CH2  . TRP B 1 133 ? 12.412  55.647  -9.468  0.33  15.168 ? 301 TRP D CH2  1 ? 
ATOM   5718 H H    . TRP B 1 133 ? 15.117  62.084  -12.638 0.33  18.616 ? 301 TRP D H    1 c 
ATOM   5719 H HA   . TRP B 1 133 ? 13.779  60.636  -10.704 0.33  17.182 ? 301 TRP D HA   1 c 
ATOM   5720 H HB2  . TRP B 1 133 ? 14.006  59.663  -12.795 0.33  16.335 ? 301 TRP D HB2  1 c 
ATOM   5721 H HB3  . TRP B 1 133 ? 15.583  59.797  -12.749 0.33  16.335 ? 301 TRP D HB3  1 c 
ATOM   5722 H HD1  . TRP B 1 133 ? 16.758  57.558  -12.195 0.33  14.593 ? 301 TRP D HD1  1 c 
ATOM   5723 H HE1  . TRP B 1 133 ? 16.192  55.511  -11.064 0.33  14.098 ? 301 TRP D HE1  1 c 
ATOM   5724 H HE3  . TRP B 1 133 ? 12.207  58.678  -10.654 0.33  15.494 ? 301 TRP D HE3  1 c 
ATOM   5725 H HZ2  . TRP B 1 133 ? 14.051  54.467  -9.675  0.33  14.773 ? 301 TRP D HZ2  1 c 
ATOM   5726 H HZ3  . TRP B 1 133 ? 10.996  57.103  -9.46   0.33  15.456 ? 301 TRP D HZ3  1 c 
ATOM   5727 H HH2  . TRP B 1 133 ? 11.905  55.025  -8.976  0.33  15.147 ? 301 TRP D HH2  1 c 
ATOM   5728 N N    . TRP B 1 134 ? 16.86   61.378  -10.293 0.33  16.125 ? 302 TRP D N    1 ? 
ATOM   5729 C CA   . TRP B 1 134 ? 18.01   61.256  -9.403  0.33  15.712 ? 302 TRP D CA   1 ? 
ATOM   5730 C C    . TRP B 1 134 ? 17.648  61.515  -7.936  0.33  15.697 ? 302 TRP D C    1 ? 
ATOM   5731 O O    . TRP B 1 134 ? 18.106  60.78   -7.076  0.33  13.816 ? 302 TRP D O    1 ? 
ATOM   5732 C CB   . TRP B 1 134 ? 19.177  62.16   -9.829  0.33  15.337 ? 302 TRP D CB   1 ? 
ATOM   5733 C CG   . TRP B 1 134 ? 20.269  62.179  -8.793  0.33  15.022 ? 302 TRP D CG   1 ? 
ATOM   5734 C CD1  . TRP B 1 134 ? 20.618  63.219  -7.989  0.33  14.46  ? 302 TRP D CD1  1 ? 
ATOM   5735 C CD2  . TRP B 1 134 ? 21.112  61.076  -8.396  0.33  14.489 ? 302 TRP D CD2  1 ? 
ATOM   5736 N NE1  . TRP B 1 134 ? 21.639  62.855  -7.156  0.33  15.096 ? 302 TRP D NE1  1 ? 
ATOM   5737 C CE2  . TRP B 1 134 ? 21.969  61.551  -7.378  0.33  14.44  ? 302 TRP D CE2  1 ? 
ATOM   5738 C CE3  . TRP B 1 134 ? 21.244  59.748  -8.81   0.33  14.234 ? 302 TRP D CE3  1 ? 
ATOM   5739 C CZ2  . TRP B 1 134 ? 22.917  60.741  -6.755  0.33  14.254 ? 302 TRP D CZ2  1 ? 
ATOM   5740 C CZ3  . TRP B 1 134 ? 22.191  58.948  -8.201  0.33  14.408 ? 302 TRP D CZ3  1 ? 
ATOM   5741 C CH2  . TRP B 1 134 ? 23.024  59.44   -7.19   0.33  14.064 ? 302 TRP D CH2  1 ? 
ATOM   5742 H H    . TRP B 1 134 ? 16.896  61.966  -10.992 0.33  16.184 ? 302 TRP D H    1 c 
ATOM   5743 H HA   . TRP B 1 134 ? 18.33   60.316  -9.467  0.33  15.719 ? 302 TRP D HA   1 c 
ATOM   5744 H HB2  . TRP B 1 134 ? 19.542  61.827  -10.677 0.33  15.347 ? 302 TRP D HB2  1 c 
ATOM   5745 H HB3  . TRP B 1 134 ? 18.84   63.072  -9.96   0.33  15.347 ? 302 TRP D HB3  1 c 
ATOM   5746 H HD1  . TRP B 1 134 ? 20.235  64.081  -8.02   0.33  14.73  ? 302 TRP D HD1  1 c 
ATOM   5747 H HE1  . TRP B 1 134 ? 22.025  63.362  -6.568  0.33  14.785 ? 302 TRP D HE1  1 c 
ATOM   5748 H HE3  . TRP B 1 134 ? 20.694  59.405  -9.493  0.33  14.336 ? 302 TRP D HE3  1 c 
ATOM   5749 H HZ2  . TRP B 1 134 ? 23.475  61.077  -6.074  0.33  14.259 ? 302 TRP D HZ2  1 c 
ATOM   5750 H HZ3  . TRP B 1 134 ? 22.283  58.051  -8.477  0.33  14.291 ? 302 TRP D HZ3  1 c 
ATOM   5751 H HH2  . TRP B 1 134 ? 23.657  58.869  -6.791  0.33  14.194 ? 302 TRP D HH2  1 c 
ATOM   5752 N N    . PRO B 1 135 ? 16.862  62.555  -7.561  0.33  15.785 ? 303 PRO D N    1 ? 
ATOM   5753 C CA   . PRO B 1 135 ? 16.488  62.756  -6.16   0.33  16.426 ? 303 PRO D CA   1 ? 
ATOM   5754 C C    . PRO B 1 135 ? 15.864  61.539  -5.475  0.33  16.281 ? 303 PRO D C    1 ? 
ATOM   5755 O O    . PRO B 1 135 ? 16.064  61.328  -4.285  0.33  17.675 ? 303 PRO D O    1 ? 
ATOM   5756 C CB   . PRO B 1 135 ? 15.511  63.943  -6.186  0.33  15.455 ? 303 PRO D CB   1 ? 
ATOM   5757 C CG   . PRO B 1 135 ? 15.815  64.67   -7.469  0.33  15.946 ? 303 PRO D CG   1 ? 
ATOM   5758 C CD   . PRO B 1 135 ? 16.421  63.666  -8.42   0.33  16.036 ? 303 PRO D CD   1 ? 
ATOM   5759 H HA   . PRO B 1 135 ? 17.303  63.023  -5.664  0.33  16.093 ? 303 PRO D HA   1 c 
ATOM   5760 H HB2  . PRO B 1 135 ? 14.577  63.627  -6.175  0.33  15.777 ? 303 PRO D HB2  1 c 
ATOM   5761 H HB3  . PRO B 1 135 ? 15.655  64.531  -5.408  0.33  15.777 ? 303 PRO D HB3  1 c 
ATOM   5762 H HG2  . PRO B 1 135 ? 14.994  65.046  -7.851  0.33  15.853 ? 303 PRO D HG2  1 c 
ATOM   5763 H HG3  . PRO B 1 135 ? 16.443  65.404  -7.305  0.33  15.853 ? 303 PRO D HG3  1 c 
ATOM   5764 H HD2  . PRO B 1 135 ? 15.754  63.359  -9.074  0.33  15.957 ? 303 PRO D HD2  1 c 
ATOM   5765 H HD3  . PRO B 1 135 ? 17.181  64.058  -8.904  0.33  15.958 ? 303 PRO D HD3  1 c 
ATOM   5766 N N    . ILE B 1 136 ? 15.087  60.76   -6.228  0.33  16.293 ? 304 ILE D N    1 ? 
ATOM   5767 C CA   . ILE B 1 136 ? 14.485  59.564  -5.665  0.33  16.736 ? 304 ILE D CA   1 ? 
ATOM   5768 C C    . ILE B 1 136 ? 15.573  58.555  -5.327  0.33  15.456 ? 304 ILE D C    1 ? 
ATOM   5769 O O    . ILE B 1 136 ? 15.599  57.995  -4.231  0.33  15.639 ? 304 ILE D O    1 ? 
ATOM   5770 C CB   . ILE B 1 136 ? 13.459  58.966  -6.638  0.33  18.114 ? 304 ILE D CB   1 ? 
ATOM   5771 C CG1  . ILE B 1 136 ? 12.294  59.913  -6.825  0.33  20.08  ? 304 ILE D CG1  1 ? 
ATOM   5772 C CG2  . ILE B 1 136 ? 13.014  57.587  -6.159  0.33  19.702 ? 304 ILE D CG2  1 ? 
ATOM   5773 C CD1  . ILE B 1 136 ? 11.546  59.689  -8.115  0.33  20.679 ? 304 ILE D CD1  1 ? 
ATOM   5774 H H    . ILE B 1 136 ? 14.928  60.975  -7.102  0.33  16.388 ? 304 ILE D H    1 c 
ATOM   5775 H HA   . ILE B 1 136 ? 14.022  59.811  -4.841  0.33  16.645 ? 304 ILE D HA   1 c 
ATOM   5776 H HB   . ILE B 1 136 ? 13.898  58.858  -7.505  0.33  18.488 ? 304 ILE D HB   1 c 
ATOM   5777 H HG12 . ILE B 1 136 ? 11.674  59.802  -6.075  0.33  19.744 ? 304 ILE D HG12 1 c 
ATOM   5778 H HG13 . ILE B 1 136 ? 12.628  60.833  -6.807  0.33  19.744 ? 304 ILE D HG13 1 c 
ATOM   5779 H HG21 . ILE B 1 136 ? 12.366  57.219  -6.783  0.33  19.221 ? 304 ILE D HG21 1 c 
ATOM   5780 H HG22 . ILE B 1 136 ? 12.606  57.664  -5.28   0.33  19.221 ? 304 ILE D HG22 1 c 
ATOM   5781 H HG23 . ILE B 1 136 ? 13.784  56.996  -6.107  0.33  19.221 ? 304 ILE D HG23 1 c 
ATOM   5782 H HD11 . ILE B 1 136 ? 12.149  59.825  -8.87   0.33  20.499 ? 304 ILE D HD11 1 c 
ATOM   5783 H HD12 . ILE B 1 136 ? 10.804  60.32   -8.176  0.33  20.499 ? 304 ILE D HD12 1 c 
ATOM   5784 H HD13 . ILE B 1 136 ? 11.198  58.778  -8.138  0.33  20.499 ? 304 ILE D HD13 1 c 
ATOM   5785 N N    . VAL B 1 137 ? 16.476  58.336  -6.283  0.33  15.119 ? 305 VAL D N    1 ? 
ATOM   5786 C CA   . VAL B 1 137 ? 17.585  57.428  -6.064  0.33  14.743 ? 305 VAL D CA   1 ? 
ATOM   5787 C C    . VAL B 1 137 ? 18.454  57.946  -4.918  0.33  14.568 ? 305 VAL D C    1 ? 
ATOM   5788 O O    . VAL B 1 137 ? 18.813  57.19   -4.018  0.33  14.172 ? 305 VAL D O    1 ? 
ATOM   5789 C CB   . VAL B 1 137 ? 18.397  57.231  -7.356  0.33  15.379 ? 305 VAL D CB   1 ? 
ATOM   5790 C CG1  . VAL B 1 137 ? 19.642  56.406  -7.085  0.33  15.604 ? 305 VAL D CG1  1 ? 
ATOM   5791 C CG2  . VAL B 1 137 ? 17.549  56.604  -8.458  0.33  15.751 ? 305 VAL D CG2  1 ? 
ATOM   5792 H H    . VAL B 1 137 ? 16.4    58.762  -7.088  0.33  15.113 ? 305 VAL D H    1 c 
ATOM   5793 H HA   . VAL B 1 137 ? 17.218  56.561  -5.801  0.33  14.898 ? 305 VAL D HA   1 c 
ATOM   5794 H HB   . VAL B 1 137 ? 18.683  58.124  -7.661  0.33  15.369 ? 305 VAL D HB   1 c 
ATOM   5795 H HG11 . VAL B 1 137 ? 19.385  55.537  -6.733  0.33  15.537 ? 305 VAL D HG11 1 c 
ATOM   5796 H HG12 . VAL B 1 137 ? 20.201  56.865  -6.436  0.33  15.537 ? 305 VAL D HG12 1 c 
ATOM   5797 H HG13 . VAL B 1 137 ? 20.138  56.286  -7.912  0.33  15.537 ? 305 VAL D HG13 1 c 
ATOM   5798 H HG21 . VAL B 1 137 ? 18.085  56.501  -9.262  0.33  15.641 ? 305 VAL D HG21 1 c 
ATOM   5799 H HG22 . VAL B 1 137 ? 16.788  57.178  -8.649  0.33  15.641 ? 305 VAL D HG22 1 c 
ATOM   5800 H HG23 . VAL B 1 137 ? 17.231  55.732  -8.168  0.33  15.641 ? 305 VAL D HG23 1 c 
ATOM   5801 N N    . GLN B 1 138 ? 18.782  59.234  -4.953  0.33  13.464 ? 306 GLN D N    1 ? 
ATOM   5802 C CA   . GLN B 1 138 ? 19.634  59.843  -3.942  0.33  13.644 ? 306 GLN D CA   1 ? 
ATOM   5803 C C    . GLN B 1 138 ? 19.036  59.678  -2.543  0.33  13.605 ? 306 GLN D C    1 ? 
ATOM   5804 O O    . GLN B 1 138 ? 19.759  59.402  -1.581  0.33  13.909 ? 306 GLN D O    1 ? 
ATOM   5805 C CB   . GLN B 1 138 ? 19.856  61.318  -4.271  0.33  13.945 ? 306 GLN D CB   1 ? 
ATOM   5806 C CG   . GLN B 1 138 ? 20.778  62.015  -3.271  0.33  14.31  ? 306 GLN D CG   1 ? 
ATOM   5807 C CD   . GLN B 1 138 ? 20.296  63.402  -2.917  0.33  13.777 ? 306 GLN D CD   1 ? 
ATOM   5808 O OE1  . GLN B 1 138 ? 19.605  64.045  -3.71   0.33  14.337 ? 306 GLN D OE1  1 ? 
ATOM   5809 N NE2  . GLN B 1 138 ? 20.637  63.863  -1.725  0.33  14.459 ? 306 GLN D NE2  1 ? 
ATOM   5810 H H    . GLN B 1 138 ? 18.464  59.756  -5.632  0.33  13.76  ? 306 GLN D H    1 c 
ATOM   5811 H HA   . GLN B 1 138 ? 20.512  59.383  -3.962  0.33  13.656 ? 306 GLN D HA   1 c 
ATOM   5812 H HB2  . GLN B 1 138 ? 20.243  61.389  -5.168  0.33  13.957 ? 306 GLN D HB2  1 c 
ATOM   5813 H HB3  . GLN B 1 138 ? 18.989  61.775  -4.281  0.33  13.957 ? 306 GLN D HB3  1 c 
ATOM   5814 H HG2  . GLN B 1 138 ? 20.834  61.478  -2.451  0.33  14.103 ? 306 GLN D HG2  1 c 
ATOM   5815 H HG3  . GLN B 1 138 ? 21.681  62.078  -3.65   0.33  14.103 ? 306 GLN D HG3  1 c 
ATOM   5816 H HE21 . GLN B 1 138 ? 20.365  64.667  -1.467  0.33  14.246 ? 306 GLN D HE21 1 c 
ATOM   5817 H HE22 . GLN B 1 138 ? 21.138  63.368  -1.186  0.33  14.246 ? 306 GLN D HE22 1 c 
ATOM   5818 N N    . GLY B 1 139 ? 17.711  59.864  -2.441  0.33  14.294 ? 307 GLY D N    1 ? 
ATOM   5819 C CA   . GLY B 1 139 ? 16.999  59.724  -1.179  0.33  14.605 ? 307 GLY D CA   1 ? 
ATOM   5820 C C    . GLY B 1 139 ? 17.158  58.329  -0.575  0.33  15.13  ? 307 GLY D C    1 ? 
ATOM   5821 O O    . GLY B 1 139 ? 17.28   58.164  0.638   0.33  15.236 ? 307 GLY D O    1 ? 
ATOM   5822 H H    . GLY B 1 139 ? 17.235  60.086  -3.189  0.33  14.196 ? 307 GLY D H    1 c 
ATOM   5823 H HA2  . GLY B 1 139 ? 17.34   60.396  -0.543  0.33  14.645 ? 307 GLY D HA2  1 c 
ATOM   5824 H HA3  . GLY B 1 139 ? 16.042  59.909  -1.329  0.33  14.645 ? 307 GLY D HA3  1 c 
ATOM   5825 N N    . ARG B 1 140 ? 17.169  57.317  -1.451  0.33  14.054 ? 308 ARG D N    1 ? 
ATOM   5826 C CA   . ARG B 1 140 ? 17.281  55.932  -1.03   0.33  14.013 ? 308 ARG D CA   1 ? 
ATOM   5827 C C    . ARG B 1 140 ? 18.704  55.628  -0.568  0.33  12.937 ? 308 ARG D C    1 ? 
ATOM   5828 O O    . ARG B 1 140 ? 18.887  54.91   0.42    0.33  12.088 ? 308 ARG D O    1 ? 
ATOM   5829 C CB   . ARG B 1 140 ? 16.826  55      -2.158  0.33  13.933 ? 308 ARG D CB   1 ? 
ATOM   5830 C CG   . ARG B 1 140 ? 15.314  55.109  -2.324  0.33  14.006 ? 308 ARG D CG   1 ? 
ATOM   5831 C CD   . ARG B 1 140 ? 14.831  54.651  -3.664  0.33  13.532 ? 308 ARG D CD   1 ? 
ATOM   5832 N NE   . ARG B 1 140 ? 13.372  54.72   -3.739  0.33  13.295 ? 308 ARG D NE   1 ? 
ATOM   5833 C CZ   . ARG B 1 140 ? 12.678  54.134  -4.702  0.33  13.538 ? 308 ARG D CZ   1 ? 
ATOM   5834 N NH1  . ARG B 1 140 ? 13.31   53.425  -5.617  0.33  13.604 ? 308 ARG D NH1  1 ? 
ATOM   5835 N NH2  . ARG B 1 140 ? 11.363  54.243  -4.737  0.33  14.459 ? 308 ARG D NH2  1 ? 
ATOM   5836 H H    . ARG B 1 140 ? 17.105  57.501  -2.344  0.33  14.294 ? 308 ARG D H    1 c 
ATOM   5837 H HA   . ARG B 1 140 ? 16.672  55.798  -0.26   0.33  13.802 ? 308 ARG D HA   1 c 
ATOM   5838 H HB2  . ARG B 1 140 ? 17.268  55.25   -2.997  0.33  13.967 ? 308 ARG D HB2  1 c 
ATOM   5839 H HB3  . ARG B 1 140 ? 17.067  54.073  -1.943  0.33  13.967 ? 308 ARG D HB3  1 c 
ATOM   5840 H HG2  . ARG B 1 140 ? 14.876  54.573  -1.629  0.33  13.878 ? 308 ARG D HG2  1 c 
ATOM   5841 H HG3  . ARG B 1 140 ? 15.045  56.044  -2.193  0.33  13.878 ? 308 ARG D HG3  1 c 
ATOM   5842 H HD2  . ARG B 1 140 ? 15.219  55.216  -4.364  0.33  13.582 ? 308 ARG D HD2  1 c 
ATOM   5843 H HD3  . ARG B 1 140 ? 15.121  53.729  -3.82   0.33  13.582 ? 308 ARG D HD3  1 c 
ATOM   5844 H HE   . ARG B 1 140 ? 12.941  55.165  -3.126  0.33  13.407 ? 308 ARG D HE   1 c 
ATOM   5845 H HH11 . ARG B 1 140 ? 14.19   53.348  -5.581  0.33  13.584 ? 308 ARG D HH11 1 c 
ATOM   5846 H HH12 . ARG B 1 140 ? 12.851  53.03   -6.261  0.33  13.584 ? 308 ARG D HH12 1 c 
ATOM   5847 H HH21 . ARG B 1 140 ? 10.944  54.704  -4.109  0.33  14.169 ? 308 ARG D HH21 1 c 
ATOM   5848 H HH22 . ARG B 1 140 ? 10.907  53.855  -5.387  0.33  14.169 ? 308 ARG D HH22 1 c 
ATOM   5849 N N    . ILE B 1 141 ? 19.691  56.196  -1.27   0.33  12.46  ? 309 ILE D N    1 ? 
ATOM   5850 C CA   . ILE B 1 141 ? 21.077  56.045  -0.851  0.33  13.876 ? 309 ILE D CA   1 ? 
ATOM   5851 C C    . ILE B 1 141 ? 21.236  56.641  0.549   0.33  13.546 ? 309 ILE D C    1 ? 
ATOM   5852 O O    . ILE B 1 141 ? 21.869  56.059  1.429   0.33  14.686 ? 309 ILE D O    1 ? 
ATOM   5853 C CB   . ILE B 1 141 ? 22.055  56.7    -1.84   0.33  13.109 ? 309 ILE D CB   1 ? 
ATOM   5854 C CG1  . ILE B 1 141 ? 21.923  56.115  -3.264  0.33  12.706 ? 309 ILE D CG1  1 ? 
ATOM   5855 C CG2  . ILE B 1 141 ? 23.477  56.565  -1.308  0.33  13.773 ? 309 ILE D CG2  1 ? 
ATOM   5856 C CD1  . ILE B 1 141 ? 22.635  56.949  -4.325  0.33  12.542 ? 309 ILE D CD1  1 ? 
ATOM   5857 H H    . ILE B 1 141 ? 19.499  56.683  -2.02   0.33  12.879 ? 309 ILE D H    1 c 
ATOM   5858 H HA   . ILE B 1 141 ? 21.281  55.091  -0.806  0.33  13.388 ? 309 ILE D HA   1 c 
ATOM   5859 H HB   . ILE B 1 141 ? 21.84   57.653  -1.887  0.33  13.294 ? 309 ILE D HB   1 c 
ATOM   5860 H HG12 . ILE B 1 141 ? 22.294  55.209  -3.271  0.33  12.757 ? 309 ILE D HG12 1 c 
ATOM   5861 H HG13 . ILE B 1 141 ? 20.973  56.054  -3.494  0.33  12.757 ? 309 ILE D HG13 1 c 
ATOM   5862 H HG21 . ILE B 1 141 ? 24.099  56.978  -1.931  0.33  13.574 ? 309 ILE D HG21 1 c 
ATOM   5863 H HG22 . ILE B 1 141 ? 23.7    55.624  -1.207  0.33  13.574 ? 309 ILE D HG22 1 c 
ATOM   5864 H HG23 . ILE B 1 141 ? 23.546  57.006  -0.445  0.33  13.574 ? 309 ILE D HG23 1 c 
ATOM   5865 H HD11 . ILE B 1 141 ? 22.254  57.847  -4.345  0.33  12.59  ? 309 ILE D HD11 1 c 
ATOM   5866 H HD12 . ILE B 1 141 ? 22.524  56.53   -5.199  0.33  12.59  ? 309 ILE D HD12 1 c 
ATOM   5867 H HD13 . ILE B 1 141 ? 23.586  57.006  -4.112  0.33  12.59  ? 309 ILE D HD13 1 c 
ATOM   5868 N N    . ASP B 1 142 ? 20.685  57.835  0.739   0.33  13.94  ? 310 ASP D N    1 ? 
ATOM   5869 C CA   . ASP B 1 142 ? 20.817  58.547  2.001   0.33  14.169 ? 310 ASP D CA   1 ? 
ATOM   5870 C C    . ASP B 1 142 ? 20.207  57.741  3.143   0.33  15.367 ? 310 ASP D C    1 ? 
ATOM   5871 O O    . ASP B 1 142 ? 20.8    57.651  4.223   0.33  14.52  ? 310 ASP D O    1 ? 
ATOM   5872 C CB   . ASP B 1 142 ? 20.229  59.937  1.91    0.33  13.634 ? 310 ASP D CB   1 ? 
ATOM   5873 C CG   . ASP B 1 142 ? 21.017  60.918  1.053   0.33  14.16  ? 310 ASP D CG   1 ? 
ATOM   5874 O OD1  . ASP B 1 142 ? 22.213  60.644  0.746   0.33  13.999 ? 310 ASP D OD1  1 ? 
ATOM   5875 O OD2  . ASP B 1 142 ? 20.395  61.911  0.636   0.33  13.471 ? 310 ASP D OD2  1 ? 
ATOM   5876 H H    . ASP B 1 142 ? 20.21   58.223  0.061   0.33  13.896 ? 310 ASP D H    1 c 
ATOM   5877 H HA   . ASP B 1 142 ? 21.777  58.657  2.186   0.33  14.233 ? 310 ASP D HA   1 c 
ATOM   5878 H HB2  . ASP B 1 142 ? 19.323  59.871  1.542   0.33  13.875 ? 310 ASP D HB2  1 c 
ATOM   5879 H HB3  . ASP B 1 142 ? 20.16   60.308  2.814   0.33  13.875 ? 310 ASP D HB3  1 c 
ATOM   5880 N N    . ARG B 1 143 ? 19.018  57.175  2.884   0.33  16.395 ? 311 ARG D N    1 ? 
ATOM   5881 C CA   . ARG B 1 143 ? 18.372  56.292  3.842   0.33  17.479 ? 311 ARG D CA   1 ? 
ATOM   5882 C C    . ARG B 1 143 ? 19.248  55.081  4.161   0.33  17.131 ? 311 ARG D C    1 ? 
ATOM   5883 O O    . ARG B 1 143 ? 19.351  54.687  5.329   0.33  20.207 ? 311 ARG D O    1 ? 
ATOM   5884 C CB   . ARG B 1 143 ? 16.987  55.873  3.334   0.33  18.058 ? 311 ARG D CB   1 ? 
ATOM   5885 C CG   . ARG B 1 143 ? 15.996  57.012  3.443   0.33  18.713 ? 311 ARG D CG   1 ? 
ATOM   5886 C CD   . ARG B 1 143 ? 15.564  57.226  4.893   0.33  19.38  ? 311 ARG D CD   1 ? 
ATOM   5887 N NE   . ARG B 1 143 ? 14.641  58.361  4.971   0.33  19.627 ? 311 ARG D NE   1 ? 
ATOM   5888 C CZ   . ARG B 1 143 ? 13.823  58.602  5.978   0.33  20.498 ? 311 ARG D CZ   1 ? 
ATOM   5889 N NH1  . ARG B 1 143 ? 13.844  57.828  7.051   0.33  20.317 ? 311 ARG D NH1  1 ? 
ATOM   5890 N NH2  . ARG B 1 143 ? 12.95   59.586  5.869   0.33  20.35  ? 311 ARG D NH2  1 ? 
ATOM   5891 H H    . ARG B 1 143 ? 18.602  57.345  2.089   0.33  16.378 ? 311 ARG D H    1 c 
ATOM   5892 H HA   . ARG B 1 143 ? 18.241  56.802  4.682   0.33  17.302 ? 311 ARG D HA   1 c 
ATOM   5893 H HB2  . ARG B 1 143 ? 17.056  55.591  2.397   0.33  18.073 ? 311 ARG D HB2  1 c 
ATOM   5894 H HB3  . ARG B 1 143 ? 16.664  55.111  3.86    0.33  18.073 ? 311 ARG D HB3  1 c 
ATOM   5895 H HG2  . ARG B 1 143 ? 16.407  57.836  3.103   0.33  18.709 ? 311 ARG D HG2  1 c 
ATOM   5896 H HG3  . ARG B 1 143 ? 15.206  56.811  2.896   0.33  18.709 ? 311 ARG D HG3  1 c 
ATOM   5897 H HD2  . ARG B 1 143 ? 15.12   56.421  5.23    0.33  19.287 ? 311 ARG D HD2  1 c 
ATOM   5898 H HD3  . ARG B 1 143 ? 16.348  57.403  5.452   0.33  19.287 ? 311 ARG D HD3  1 c 
ATOM   5899 H HE   . ARG B 1 143 ? 14.63   58.921  4.304   0.33  19.772 ? 311 ARG D HE   1 c 
ATOM   5900 H HH11 . ARG B 1 143 ? 14.395  57.137  7.083   0.33  20.373 ? 311 ARG D HH11 1 c 
ATOM   5901 H HH12 . ARG B 1 143 ? 13.308  58.005  7.731   0.33  20.373 ? 311 ARG D HH12 1 c 
ATOM   5902 H HH21 . ARG B 1 143 ? 12.924  60.071  5.131   0.33  20.396 ? 311 ARG D HH21 1 c 
ATOM   5903 H HH22 . ARG B 1 143 ? 12.394  59.756  6.536   0.33  20.396 ? 311 ARG D HH22 1 c 
ATOM   5904 N N    . ALA B 1 144 ? 19.854  54.476  3.128   0.33  15.635 ? 312 ALA D N    1 ? 
ATOM   5905 C CA   . ALA B 1 144 ? 20.692  53.307  3.329   0.33  14.707 ? 312 ALA D CA   1 ? 
ATOM   5906 C C    . ALA B 1 144 ? 21.858  53.678  4.24    0.33  14.432 ? 312 ALA D C    1 ? 
ATOM   5907 O O    . ALA B 1 144 ? 22.224  52.911  5.123   0.33  12.708 ? 312 ALA D O    1 ? 
ATOM   5908 C CB   . ALA B 1 144 ? 21.173  52.738  2.001   0.33  14.411 ? 312 ALA D CB   1 ? 
ATOM   5909 H H    . ALA B 1 144 ? 19.74   54.802  2.282   0.33  15.761 ? 312 ALA D H    1 c 
ATOM   5910 H HA   . ALA B 1 144 ? 20.146  52.616  3.796   0.33  14.777 ? 312 ALA D HA   1 c 
ATOM   5911 H HB1  . ALA B 1 144 ? 20.409  52.485  1.457   0.33  14.497 ? 312 ALA D HB1  1 c 
ATOM   5912 H HB2  . ALA B 1 144 ? 21.696  53.407  1.529   0.33  14.497 ? 312 ALA D HB2  1 c 
ATOM   5913 H HB3  . ALA B 1 144 ? 21.726  51.954  2.163   0.33  14.497 ? 312 ALA D HB3  1 c 
ATOM   5914 N N    . LEU B 1 145 ? 22.448  54.849  4.006   0.33  13.064 ? 313 LEU D N    1 ? 
ATOM   5915 C CA   . LEU B 1 145 ? 23.6    55.283  4.782   0.33  14.722 ? 313 LEU D CA   1 ? 
ATOM   5916 C C    . LEU B 1 145 ? 23.165  55.62   6.206   0.33  15.037 ? 313 LEU D C    1 ? 
ATOM   5917 O O    . LEU B 1 145 ? 23.844  55.306  7.171   0.33  15.311 ? 313 LEU D O    1 ? 
ATOM   5918 C CB   . LEU B 1 145 ? 24.167  56.508  4.073   0.33  14.13  ? 313 LEU D CB   1 ? 
ATOM   5919 C CG   . LEU B 1 145 ? 24.924  56.256  2.77    0.33  14.458 ? 313 LEU D CG   1 ? 
ATOM   5920 C CD1  . LEU B 1 145 ? 25.074  57.581  2.033   0.33  14.631 ? 313 LEU D CD1  1 ? 
ATOM   5921 C CD2  . LEU B 1 145 ? 26.288  55.648  3.019   0.33  14.421 ? 313 LEU D CD2  1 ? 
ATOM   5922 H H    . LEU B 1 145 ? 22.127  55.393  3.346   0.33  13.742 ? 313 LEU D H    1 c 
ATOM   5923 H HA   . LEU B 1 145 ? 24.275  54.558  4.797   0.33  14.332 ? 313 LEU D HA   1 c 
ATOM   5924 H HB2  . LEU B 1 145 ? 23.421  57.123  3.883   0.33  14.338 ? 313 LEU D HB2  1 c 
ATOM   5925 H HB3  . LEU B 1 145 ? 24.773  56.969  4.698   0.33  14.338 ? 313 LEU D HB3  1 c 
ATOM   5926 H HG   . LEU B 1 145 ? 24.392  55.635  2.208   0.33  14.422 ? 313 LEU D HG   1 c 
ATOM   5927 H HD11 . LEU B 1 145 ? 24.195  57.942  1.83    0.33  14.58  ? 313 LEU D HD11 1 c 
ATOM   5928 H HD12 . LEU B 1 145 ? 25.563  57.439  1.205   0.33  14.58  ? 313 LEU D HD12 1 c 
ATOM   5929 H HD13 . LEU B 1 145 ? 25.561  58.21   2.591   0.33  14.58  ? 313 LEU D HD13 1 c 
ATOM   5930 H HD21 . LEU B 1 145 ? 26.186  54.802  3.487   0.33  14.432 ? 313 LEU D HD21 1 c 
ATOM   5931 H HD22 . LEU B 1 145 ? 26.82   56.255  3.561   0.33  14.432 ? 313 LEU D HD22 1 c 
ATOM   5932 H HD23 . LEU B 1 145 ? 26.736  55.496  2.17    0.33  14.432 ? 313 LEU D HD23 1 c 
ATOM   5933 N N    . ALA B 1 146 ? 22.014  56.27   6.334   0.33  15.427 ? 314 ALA D N    1 ? 
ATOM   5934 C CA   . ALA B 1 146 ? 21.534  56.69   7.641   0.33  16.272 ? 314 ALA D CA   1 ? 
ATOM   5935 C C    . ALA B 1 146 ? 21.23   55.497  8.556   0.33  16.462 ? 314 ALA D C    1 ? 
ATOM   5936 O O    . ALA B 1 146 ? 21.29   55.617  9.779   0.33  17.015 ? 314 ALA D O    1 ? 
ATOM   5937 C CB   . ALA B 1 146 ? 20.328  57.559  7.472   0.33  16.16  ? 314 ALA D CB   1 ? 
ATOM   5938 H H    . ALA B 1 146 ? 21.513  56.459  5.594   0.33  15.518 ? 314 ALA D H    1 c 
ATOM   5939 H HA   . ALA B 1 146 ? 22.256  57.227  8.071   0.33  16.117 ? 314 ALA D HA   1 c 
ATOM   5940 H HB1  . ALA B 1 146 ? 20.56   58.342  6.944   0.33  16.194 ? 314 ALA D HB1  1 c 
ATOM   5941 H HB2  . ALA B 1 146 ? 19.627  57.062  7.017   0.33  16.194 ? 314 ALA D HB2  1 c 
ATOM   5942 H HB3  . ALA B 1 146 ? 20.005  57.844  8.343   0.33  16.194 ? 314 ALA D HB3  1 c 
ATOM   5943 N N    . ALA B 1 147 ? 20.894  54.343  7.973   0.33  16.028 ? 315 ALA D N    1 ? 
ATOM   5944 C CA   . ALA B 1 147 ? 20.579  53.163  8.77    0.33  15.526 ? 315 ALA D CA   1 ? 
ATOM   5945 C C    . ALA B 1 147 ? 21.815  52.272  8.898   0.33  15.674 ? 315 ALA D C    1 ? 
ATOM   5946 O O    . ALA B 1 147 ? 21.756  51.246  9.568   0.33  17.266 ? 315 ALA D O    1 ? 
ATOM   5947 C CB   . ALA B 1 147 ? 19.417  52.405  8.158   0.33  14.981 ? 315 ALA D CB   1 ? 
ATOM   5948 H H    . ALA B 1 147 ? 20.858  54.287  7.061   0.33  16.016 ? 315 ALA D H    1 c 
ATOM   5949 H HA   . ALA B 1 147 ? 20.322  53.468  9.684   0.33  15.548 ? 315 ALA D HA   1 c 
ATOM   5950 H HB1  . ALA B 1 147 ? 18.634  52.98   8.122   0.33  15.14  ? 315 ALA D HB1  1 c 
ATOM   5951 H HB2  . ALA B 1 147 ? 19.649  52.122  7.258   0.33  15.14  ? 315 ALA D HB2  1 c 
ATOM   5952 H HB3  . ALA B 1 147 ? 19.216  51.623  8.699   0.33  15.14  ? 315 ALA D HB3  1 c 
ATOM   5953 N N    . GLY B 1 148 ? 22.919  52.649  8.242   0.33  15.639 ? 316 GLY D N    1 ? 
ATOM   5954 C CA   . GLY B 1 148 ? 24.185  51.948  8.393   0.33  14.611 ? 316 GLY D CA   1 ? 
ATOM   5955 C C    . GLY B 1 148 ? 24.239  50.63   7.616   0.33  14.651 ? 316 GLY D C    1 ? 
ATOM   5956 O O    . GLY B 1 148 ? 24.976  49.714  7.994   0.33  14.987 ? 316 GLY D O    1 ? 
ATOM   5957 H H    . GLY B 1 148 ? 22.88   53.37   7.68    0.33  15.409 ? 316 GLY D H    1 c 
ATOM   5958 H HA2  . GLY B 1 148 ? 24.913  52.536  8.084   0.33  14.859 ? 316 GLY D HA2  1 c 
ATOM   5959 H HA3  . GLY B 1 148 ? 24.333  51.766  9.351   0.33  14.859 ? 316 GLY D HA3  1 c 
ATOM   5960 N N    . PHE B 1 149 ? 23.469  50.532  6.524   0.33  13.904 ? 317 PHE D N    1 ? 
ATOM   5961 C CA   . PHE B 1 149 ? 23.599  49.401  5.615   0.33  13.725 ? 317 PHE D CA   1 ? 
ATOM   5962 C C    . PHE B 1 149 ? 25.028  49.327  5.097   0.33  14.457 ? 317 PHE D C    1 ? 
ATOM   5963 O O    . PHE B 1 149 ? 25.713  50.348  4.998   0.33  15.628 ? 317 PHE D O    1 ? 
ATOM   5964 C CB   . PHE B 1 149 ? 22.641  49.519  4.428   0.33  12.922 ? 317 PHE D CB   1 ? 
ATOM   5965 C CG   . PHE B 1 149 ? 21.202  49.143  4.736   0.33  12.509 ? 317 PHE D CG   1 ? 
ATOM   5966 C CD1  . PHE B 1 149 ? 20.329  50.07   5.284   0.33  12.313 ? 317 PHE D CD1  1 ? 
ATOM   5967 C CD2  . PHE B 1 149 ? 20.72   47.878  4.451   0.33  11.785 ? 317 PHE D CD2  1 ? 
ATOM   5968 C CE1  . PHE B 1 149 ? 19.013  49.74   5.549   0.33  12.139 ? 317 PHE D CE1  1 ? 
ATOM   5969 C CE2  . PHE B 1 149 ? 19.395  47.551  4.716   0.33  11.344 ? 317 PHE D CE2  1 ? 
ATOM   5970 C CZ   . PHE B 1 149 ? 18.555  48.472  5.279   0.33  11.969 ? 317 PHE D CZ   1 ? 
ATOM   5971 H H    . PHE B 1 149 ? 22.852  51.181  6.343   0.33  14.038 ? 317 PHE D H    1 c 
ATOM   5972 H HA   . PHE B 1 149 ? 23.393  48.566  6.112   0.33  13.74  ? 317 PHE D HA   1 c 
ATOM   5973 H HB2  . PHE B 1 149 ? 22.662  50.446  4.103   0.33  13.003 ? 317 PHE D HB2  1 c 
ATOM   5974 H HB3  . PHE B 1 149 ? 22.97   48.941  3.704   0.33  13.003 ? 317 PHE D HB3  1 c 
ATOM   5975 H HD1  . PHE B 1 149 ? 20.639  50.939  5.48    0.33  12.309 ? 317 PHE D HD1  1 c 
ATOM   5976 H HD2  . PHE B 1 149 ? 21.296  47.234  4.07    0.33  11.854 ? 317 PHE D HD2  1 c 
ATOM   5977 H HE1  . PHE B 1 149 ? 18.435  50.379  5.933   0.33  12.135 ? 317 PHE D HE1  1 c 
ATOM   5978 H HE2  . PHE B 1 149 ? 19.081  46.681  4.529   0.33  11.607 ? 317 PHE D HE2  1 c 
ATOM   5979 H HZ   . PHE B 1 149 ? 17.656  48.246  5.457   0.33  11.865 ? 317 PHE D HZ   1 c 
ATOM   5980 N N    . ASN B 1 150 ? 25.447  48.119  4.712   0.33  13.851 ? 318 ASN D N    1 ? 
ATOM   5981 C CA   . ASN B 1 150 ? 26.77   47.9    4.16    0.33  15     ? 318 ASN D CA   1 ? 
ATOM   5982 C C    . ASN B 1 150 ? 26.835  48.298  2.69    0.33  13.919 ? 318 ASN D C    1 ? 
ATOM   5983 O O    . ASN B 1 150 ? 27.924  48.423  2.131   0.33  13.334 ? 318 ASN D O    1 ? 
ATOM   5984 C CB   . ASN B 1 150 ? 27.186  46.44   4.303   0.33  17.196 ? 318 ASN D CB   1 ? 
ATOM   5985 C CG   . ASN B 1 150 ? 27.481  46.108  5.741   0.33  17.808 ? 318 ASN D CG   1 ? 
ATOM   5986 O OD1  . ASN B 1 150 ? 26.701  45.42   6.406   0.33  21.624 ? 318 ASN D OD1  1 ? 
ATOM   5987 N ND2  . ASN B 1 150 ? 28.596  46.615  6.242   0.33  19.83  ? 318 ASN D ND2  1 ? 
ATOM   5988 H H    . ASN B 1 150 ? 24.883  47.405  4.798   0.33  14.248 ? 318 ASN D H    1 c 
ATOM   5989 H HA   . ASN B 1 150 ? 27.413  48.447  4.666   0.33  14.942 ? 318 ASN D HA   1 c 
ATOM   5990 H HB2  . ASN B 1 150 ? 26.468  45.863  3.976   0.33  16.807 ? 318 ASN D HB2  1 c 
ATOM   5991 H HB3  . ASN B 1 150 ? 27.984  46.274  3.761   0.33  16.807 ? 318 ASN D HB3  1 c 
ATOM   5992 H HD21 . ASN B 1 150 ? 28.815  46.454  7.086   0.33  19.184 ? 318 ASN D HD21 1 c 
ATOM   5993 H HD22 . ASN B 1 150 ? 29.122  47.116  5.733   0.33  19.184 ? 318 ASN D HD22 1 c 
ATOM   5994 N N    . GLY B 1 151 ? 25.659  48.441  2.073   0.33  13.434 ? 319 GLY D N    1 ? 
ATOM   5995 C CA   . GLY B 1 151 ? 25.605  48.68   0.65    0.33  13.803 ? 319 GLY D CA   1 ? 
ATOM   5996 C C    . GLY B 1 151 ? 24.174  48.659  0.132   0.33  13.216 ? 319 GLY D C    1 ? 
ATOM   5997 O O    . GLY B 1 151 ? 23.22   48.585  0.906   0.33  12.802 ? 319 GLY D O    1 ? 
ATOM   5998 H H    . GLY B 1 151 ? 24.881  48.388  2.55    0.33  13.631 ? 319 GLY D H    1 c 
ATOM   5999 H HA2  . GLY B 1 151 ? 26.014  49.556  0.454   0.33  13.582 ? 319 GLY D HA2  1 c 
ATOM   6000 H HA3  . GLY B 1 151 ? 26.133  47.988  0.187   0.33  13.582 ? 319 GLY D HA3  1 c 
ATOM   6001 N N    . CYS B 1 152 ? 24.075  48.719  -1.197  0.33  12.845 ? 320 CYS D N    1 ? 
ATOM   6002 C CA   . CYS B 1 152 ? 22.809  48.735  -1.904  0.33  12.955 ? 320 CYS D CA   1 ? 
ATOM   6003 C C    . CYS B 1 152 ? 22.739  47.564  -2.882  0.33  11.864 ? 320 CYS D C    1 ? 
ATOM   6004 O O    . CYS B 1 152 ? 23.754  47.054  -3.365  0.33  12.018 ? 320 CYS D O    1 ? 
ATOM   6005 C CB   . CYS B 1 152 ? 22.542  50.088  -2.561  0.33  14.009 ? 320 CYS D CB   1 ? 
ATOM   6006 S SG   . CYS B 1 152 ? 23.734  50.551  -3.834  0.33  15.826 ? 320 CYS D SG   1 ? 
ATOM   6007 H H    . CYS B 1 152 ? 24.845  48.751  -1.689  0.33  12.957 ? 320 CYS D H    1 c 
ATOM   6008 H HA   . CYS B 1 152 ? 22.096  48.604  -1.229  0.33  12.913 ? 320 CYS D HA   1 c 
ATOM   6009 H HB2  . CYS B 1 152 ? 21.647  50.074  -2.967  0.33  14.074 ? 320 CYS D HB2  1 c 
ATOM   6010 H HB3  . CYS B 1 152 ? 22.546  50.785  -1.868  0.33  14.074 ? 320 CYS D HB3  1 c 
ATOM   6011 N N    . TYR B 1 153 ? 21.5    47.167  -3.163  0.33  11.193 ? 321 TYR D N    1 ? 
ATOM   6012 C CA   . TYR B 1 153 ? 21.204  46.098  -4.099  0.33  10.866 ? 321 TYR D CA   1 ? 
ATOM   6013 C C    . TYR B 1 153 ? 20.161  46.651  -5.067  0.33  10.593 ? 321 TYR D C    1 ? 
ATOM   6014 O O    . TYR B 1 153 ? 19.028  46.919  -4.679  0.33  9.871  ? 321 TYR D O    1 ? 
ATOM   6015 C CB   . TYR B 1 153 ? 20.773  44.865  -3.301  0.33  10.354 ? 321 TYR D CB   1 ? 
ATOM   6016 C CG   . TYR B 1 153 ? 20.566  43.611  -4.138  0.33  10.572 ? 321 TYR D CG   1 ? 
ATOM   6017 C CD1  . TYR B 1 153 ? 19.346  43.348  -4.734  0.33  10.101 ? 321 TYR D CD1  1 ? 
ATOM   6018 C CD2  . TYR B 1 153 ? 21.6    42.708  -4.349  0.33  10.099 ? 321 TYR D CD2  1 ? 
ATOM   6019 C CE1  . TYR B 1 153 ? 19.157  42.212  -5.5    0.33  10.129 ? 321 TYR D CE1  1 ? 
ATOM   6020 C CE2  . TYR B 1 153 ? 21.43   41.576  -5.127  0.33  10.288 ? 321 TYR D CE2  1 ? 
ATOM   6021 C CZ   . TYR B 1 153 ? 20.198  41.324  -5.704  0.33  10.175 ? 321 TYR D CZ   1 ? 
ATOM   6022 O OH   . TYR B 1 153 ? 20.013  40.196  -6.464  0.33  10.099 ? 321 TYR D OH   1 ? 
ATOM   6023 H H    . TYR B 1 153 ? 20.802  47.586  -2.747  0.33  11.273 ? 321 TYR D H    1 c 
ATOM   6024 H HA   . TYR B 1 153 ? 22.031  45.88   -4.606  0.33  10.783 ? 321 TYR D HA   1 c 
ATOM   6025 H HB2  . TYR B 1 153 ? 21.457  44.681  -2.619  0.33  10.518 ? 321 TYR D HB2  1 c 
ATOM   6026 H HB3  . TYR B 1 153 ? 19.934  45.075  -2.834  0.33  10.518 ? 321 TYR D HB3  1 c 
ATOM   6027 H HD1  . TYR B 1 153 ? 18.626  43.946  -4.604  0.33  10.215 ? 321 TYR D HD1  1 c 
ATOM   6028 H HD2  . TYR B 1 153 ? 22.445  42.876  -3.962  0.33  10.249 ? 321 TYR D HD2  1 c 
ATOM   6029 H HE1  . TYR B 1 153 ? 18.318  42.046  -5.894  0.33  10.137 ? 321 TYR D HE1  1 c 
ATOM   6030 H HE2  . TYR B 1 153 ? 22.142  40.973  -5.252  0.33  10.218 ? 321 TYR D HE2  1 c 
ATOM   6031 N N    . LEU B 1 154 ? 20.594  46.907  -6.3    0.33  11.049 ? 322 LEU D N    1 ? 
ATOM   6032 C CA   . LEU B 1 154 ? 19.882  47.802  -7.192  0.33  10.796 ? 322 LEU D CA   1 ? 
ATOM   6033 C C    . LEU B 1 154 ? 19.073  47.001  -8.199  0.33  11.352 ? 322 LEU D C    1 ? 
ATOM   6034 O O    . LEU B 1 154 ? 19.651  46.304  -9.023  0.33  10.763 ? 322 LEU D O    1 ? 
ATOM   6035 C CB   . LEU B 1 154 ? 20.916  48.668  -7.897  0.33  11.179 ? 322 LEU D CB   1 ? 
ATOM   6036 C CG   . LEU B 1 154 ? 21.831  49.477  -6.97   0.33  11.375 ? 322 LEU D CG   1 ? 
ATOM   6037 C CD1  . LEU B 1 154 ? 22.859  50.249  -7.803  0.33  11.564 ? 322 LEU D CD1  1 ? 
ATOM   6038 C CD2  . LEU B 1 154 ? 21.032  50.429  -6.09   0.33  11.489 ? 322 LEU D CD2  1 ? 
ATOM   6039 H H    . LEU B 1 154 ? 21.361  46.508  -6.596  0.33  10.881 ? 322 LEU D H    1 c 
ATOM   6040 H HA   . LEU B 1 154 ? 19.274  48.373  -6.657  0.33  11.014 ? 322 LEU D HA   1 c 
ATOM   6041 H HB2  . LEU B 1 154 ? 21.477  48.084  -8.458  0.33  11.134 ? 322 LEU D HB2  1 c 
ATOM   6042 H HB3  . LEU B 1 154 ? 20.441  49.294  -8.491  0.33  11.134 ? 322 LEU D HB3  1 c 
ATOM   6043 H HG   . LEU B 1 154 ? 22.318  48.844  -6.382  0.33  11.394 ? 322 LEU D HG   1 c 
ATOM   6044 H HD11 . LEU B 1 154 ? 23.388  49.624  -8.326  0.33  11.509 ? 322 LEU D HD11 1 c 
ATOM   6045 H HD12 . LEU B 1 154 ? 23.444  50.752  -7.211  0.33  11.509 ? 322 LEU D HD12 1 c 
ATOM   6046 H HD13 . LEU B 1 154 ? 22.399  50.862  -8.4    0.33  11.509 ? 322 LEU D HD13 1 c 
ATOM   6047 H HD21 . LEU B 1 154 ? 20.408  49.921  -5.544  0.33  11.455 ? 322 LEU D HD21 1 c 
ATOM   6048 H HD22 . LEU B 1 154 ? 20.537  51.051  -6.65   0.33  11.455 ? 322 LEU D HD22 1 c 
ATOM   6049 H HD23 . LEU B 1 154 ? 21.637  50.924  -5.513  0.33  11.455 ? 322 LEU D HD23 1 c 
ATOM   6050 N N    . ASP B 1 155 ? 17.76   47.221  -8.204  0.33  12.145 ? 323 ASP D N    1 ? 
ATOM   6051 C CA   . ASP B 1 155 ? 16.868  46.468  -9.068  0.33  13.43  ? 323 ASP D CA   1 ? 
ATOM   6052 C C    . ASP B 1 155 ? 16.406  47.311  -10.265 0.33  15.096 ? 323 ASP D C    1 ? 
ATOM   6053 O O    . ASP B 1 155 ? 16.528  48.541  -10.3   0.33  16.653 ? 323 ASP D O    1 ? 
ATOM   6054 C CB   . ASP B 1 155 ? 15.722  45.85   -8.267  0.33  13.441 ? 323 ASP D CB   1 ? 
ATOM   6055 C CG   . ASP B 1 155 ? 14.981  44.723  -8.98   0.33  14.02  ? 323 ASP D CG   1 ? 
ATOM   6056 O OD1  . ASP B 1 155 ? 15.541  44.19   -9.946  0.33  13.219 ? 323 ASP D OD1  1 ? 
ATOM   6057 O OD2  . ASP B 1 155 ? 13.847  44.403  -8.575  0.33  16.398 ? 323 ASP D OD2  1 ? 
ATOM   6058 H H    . ASP B 1 155 ? 17.409  47.859  -7.653  0.33  12.225 ? 323 ASP D H    1 c 
ATOM   6059 H HA   . ASP B 1 155 ? 17.379  45.706  -9.425  0.33  13.458 ? 323 ASP D HA   1 c 
ATOM   6060 H HB2  . ASP B 1 155 ? 16.079  45.497  -7.425  0.33  13.569 ? 323 ASP D HB2  1 c 
ATOM   6061 H HB3  . ASP B 1 155 ? 15.074  46.553  -8.05   0.33  13.569 ? 323 ASP D HB3  1 c 
ATOM   6062 N N    . MET B 1 156 ? 15.894  46.592  -11.268 0.33  15.151 ? 324 MET D N    1 ? 
ATOM   6063 C CA   . MET B 1 156 ? 15.353  47.151  -12.499 0.33  15.501 ? 324 MET D CA   1 ? 
ATOM   6064 C C    . MET B 1 156 ? 16.43   47.864  -13.313 0.33  14.675 ? 324 MET D C    1 ? 
ATOM   6065 O O    . MET B 1 156 ? 16.142  48.8    -14.067 0.33  14.154 ? 324 MET D O    1 ? 
ATOM   6066 C CB   . MET B 1 156 ? 14.121  48.023  -12.237 0.33  15.896 ? 324 MET D CB   1 ? 
ATOM   6067 C CG   . MET B 1 156 ? 12.945  47.246  -11.658 0.33  17.395 ? 324 MET D CG   1 ? 
ATOM   6068 S SD   . MET B 1 156 ? 12.494  45.807  -12.657 0.33  19.643 ? 324 MET D SD   1 ? 
ATOM   6069 C CE   . MET B 1 156 ? 12.014  46.522  -14.239 0.33  21.276 ? 324 MET D CE   1 ? 
ATOM   6070 H H    . MET B 1 156 ? 15.882  45.683  -11.173 0.33  15.216 ? 324 MET D H    1 c 
ATOM   6071 H HA   . MET B 1 156 ? 15.06   46.38   -13.049 0.33  15.346 ? 324 MET D HA   1 c 
ATOM   6072 H HB2  . MET B 1 156 ? 14.369  48.74   -11.614 0.33  16.133 ? 324 MET D HB2  1 c 
ATOM   6073 H HB3  . MET B 1 156 ? 13.845  48.441  -13.081 0.33  16.133 ? 324 MET D HB3  1 c 
ATOM   6074 H HG2  . MET B 1 156 ? 13.171  46.943  -10.756 0.33  17.422 ? 324 MET D HG2  1 c 
ATOM   6075 H HG3  . MET B 1 156 ? 12.169  47.837  -11.591 0.33  17.422 ? 324 MET D HG3  1 c 
ATOM   6076 H HE1  . MET B 1 156 ? 11.753  45.81   -14.851 0.33  20.857 ? 324 MET D HE1  1 c 
ATOM   6077 H HE2  . MET B 1 156 ? 11.263  47.13   -14.106 0.33  20.857 ? 324 MET D HE2  1 c 
ATOM   6078 H HE3  . MET B 1 156 ? 12.768  47.014  -14.615 0.33  20.857 ? 324 MET D HE3  1 c 
ATOM   6079 N N    . VAL B 1 157 ? 17.653  47.338  -13.223 0.33  14.549 ? 325 VAL D N    1 ? 
ATOM   6080 C CA   . VAL B 1 157 ? 18.69   47.637  -14.193 0.33  14.939 ? 325 VAL D CA   1 ? 
ATOM   6081 C C    . VAL B 1 157 ? 18.205  47.247  -15.599 0.33  16.093 ? 325 VAL D C    1 ? 
ATOM   6082 O O    . VAL B 1 157 ? 18.497  47.929  -16.586 0.33  14.257 ? 325 VAL D O    1 ? 
ATOM   6083 C CB   . VAL B 1 157 ? 20.003  46.936  -13.799 0.33  14.113 ? 325 VAL D CB   1 ? 
ATOM   6084 C CG1  . VAL B 1 157 ? 21.135  47.208  -14.778 0.33  14.94  ? 325 VAL D CG1  1 ? 
ATOM   6085 C CG2  . VAL B 1 157 ? 20.437  47.307  -12.378 0.33  14.576 ? 325 VAL D CG2  1 ? 
ATOM   6086 H H    . VAL B 1 157 ? 17.846  46.772  -12.531 0.33  14.666 ? 325 VAL D H    1 c 
ATOM   6087 H HA   . VAL B 1 157 ? 18.845  48.601  -14.181 0.33  14.91  ? 325 VAL D HA   1 c 
ATOM   6088 H HB   . VAL B 1 157 ? 19.827  45.966  -13.812 0.33  14.502 ? 325 VAL D HB   1 c 
ATOM   6089 H HG11 . VAL B 1 157 ? 21.307  48.164  -14.818 0.33  14.691 ? 325 VAL D HG11 1 c 
ATOM   6090 H HG12 . VAL B 1 157 ? 20.885  46.888  -15.661 0.33  14.691 ? 325 VAL D HG12 1 c 
ATOM   6091 H HG13 . VAL B 1 157 ? 21.938  46.747  -14.483 0.33  14.691 ? 325 VAL D HG13 1 c 
ATOM   6092 H HG21 . VAL B 1 157 ? 21.268  46.852  -12.162 0.33  14.438 ? 325 VAL D HG21 1 c 
ATOM   6093 H HG22 . VAL B 1 157 ? 19.748  47.037  -11.747 0.33  14.438 ? 325 VAL D HG22 1 c 
ATOM   6094 H HG23 . VAL B 1 157 ? 20.57   48.268  -12.319 0.33  14.438 ? 325 VAL D HG23 1 c 
ATOM   6095 N N    . VAL B 1 158 ? 17.431  46.156  -15.677 0.33  16.706 ? 326 VAL D N    1 ? 
ATOM   6096 C CA   . VAL B 1 158 ? 16.934  45.616  -16.94  0.33  17.036 ? 326 VAL D CA   1 ? 
ATOM   6097 C C    . VAL B 1 158 ? 16.054  46.622  -17.686 0.33  17.958 ? 326 VAL D C    1 ? 
ATOM   6098 O O    . VAL B 1 158 ? 15.71   46.383  -18.843 0.33  19.343 ? 326 VAL D O    1 ? 
ATOM   6099 C CB   . VAL B 1 158 ? 16.153  44.302  -16.739 0.33  16.834 ? 326 VAL D CB   1 ? 
ATOM   6100 C CG1  . VAL B 1 158 ? 17.053  43.196  -16.211 0.33  17.357 ? 326 VAL D CG1  1 ? 
ATOM   6101 C CG2  . VAL B 1 158 ? 14.926  44.489  -15.854 0.33  16.685 ? 326 VAL D CG2  1 ? 
ATOM   6102 H H    . VAL B 1 158 ? 17.203  45.727  -14.903 0.33  16.631 ? 326 VAL D H    1 c 
ATOM   6103 H HA   . VAL B 1 158 ? 17.708  45.421  -17.503 0.33  17.1   ? 326 VAL D HA   1 c 
ATOM   6104 H HB   . VAL B 1 158 ? 15.833  44.02   -17.628 0.33  16.94  ? 326 VAL D HB   1 c 
ATOM   6105 H HG11 . VAL B 1 158 ? 17.423  43.46   -15.351 0.33  17.201 ? 326 VAL D HG11 1 c 
ATOM   6106 H HG12 . VAL B 1 158 ? 17.778  43.038  -16.839 0.33  17.201 ? 326 VAL D HG12 1 c 
ATOM   6107 H HG13 . VAL B 1 158 ? 16.536  42.38   -16.102 0.33  17.201 ? 326 VAL D HG13 1 c 
ATOM   6108 H HG21 . VAL B 1 158 ? 14.471  43.637  -15.744 0.33  16.729 ? 326 VAL D HG21 1 c 
ATOM   6109 H HG22 . VAL B 1 158 ? 14.321  45.127  -16.268 0.33  16.729 ? 326 VAL D HG22 1 c 
ATOM   6110 H HG23 . VAL B 1 158 ? 15.201  44.822  -14.983 0.33  16.729 ? 326 VAL D HG23 1 c 
ATOM   6111 N N    . THR B 1 159 ? 15.612  47.682  -17.007 0.33  18.446 ? 327 THR D N    1 ? 
ATOM   6112 C CA   . THR B 1 159 ? 14.8    48.711  -17.632 0.33  18.836 ? 327 THR D CA   1 ? 
ATOM   6113 C C    . THR B 1 159 ? 15.478  49.176  -18.92  0.33  19.122 ? 327 THR D C    1 ? 
ATOM   6114 O O    . THR B 1 159 ? 14.799  49.443  -19.906 0.33  18.539 ? 327 THR D O    1 ? 
ATOM   6115 C CB   . THR B 1 159 ? 14.568  49.857  -16.653 0.33  18.593 ? 327 THR D CB   1 ? 
ATOM   6116 O OG1  . THR B 1 159 ? 13.657  49.356  -15.683 0.33  17.695 ? 327 THR D OG1  1 ? 
ATOM   6117 C CG2  . THR B 1 159 ? 13.935  51.08   -17.292 0.33  18.854 ? 327 THR D CG2  1 ? 
ATOM   6118 H H    . THR B 1 159 ? 15.825  47.767  -16.123 0.33  18.415 ? 327 THR D H    1 c 
ATOM   6119 H HA   . THR B 1 159 ? 13.93   48.317  -17.861 0.33  18.766 ? 327 THR D HA   1 c 
ATOM   6120 H HB   . THR B 1 159 ? 15.416  50.107  -16.214 0.33  18.503 ? 327 THR D HB   1 c 
ATOM   6121 H HG21 . THR B 1 159 ? 13.81   51.77   -16.619 0.33  18.776 ? 327 THR D HG21 1 c 
ATOM   6122 H HG22 . THR B 1 159 ? 13.073  50.839  -17.671 0.33  18.776 ? 327 THR D HG22 1 c 
ATOM   6123 H HG23 . THR B 1 159 ? 14.515  51.416  -17.996 0.33  18.776 ? 327 THR D HG23 1 c 
ATOM   6124 N N    . TYR B 1 160 ? 16.814  49.198  -18.937 0.33  20.076 ? 328 TYR D N    1 ? 
ATOM   6125 C CA   . TYR B 1 160 ? 17.534  49.749  -20.075 0.33  21.556 ? 328 TYR D CA   1 ? 
ATOM   6126 C C    . TYR B 1 160 ? 17.173  49      -21.364 0.33  23.246 ? 328 TYR D C    1 ? 
ATOM   6127 O O    . TYR B 1 160 ? 17.251  49.571  -22.453 0.33  23.398 ? 328 TYR D O    1 ? 
ATOM   6128 C CB   . TYR B 1 160 ? 19.053  49.739  -19.877 0.33  20.859 ? 328 TYR D CB   1 ? 
ATOM   6129 C CG   . TYR B 1 160 ? 19.749  48.511  -20.429 0.33  20.794 ? 328 TYR D CG   1 ? 
ATOM   6130 C CD1  . TYR B 1 160 ? 19.889  47.365  -19.658 0.33  20.555 ? 328 TYR D CD1  1 ? 
ATOM   6131 C CD2  . TYR B 1 160 ? 20.241  48.487  -21.729 0.33  20.926 ? 328 TYR D CD2  1 ? 
ATOM   6132 C CE1  . TYR B 1 160 ? 20.526  46.242  -20.153 0.33  19.93  ? 328 TYR D CE1  1 ? 
ATOM   6133 C CE2  . TYR B 1 160 ? 20.853  47.362  -22.242 0.33  21.27  ? 328 TYR D CE2  1 ? 
ATOM   6134 C CZ   . TYR B 1 160 ? 20.985  46.234  -21.457 0.33  21.627 ? 328 TYR D CZ   1 ? 
ATOM   6135 O OH   . TYR B 1 160 ? 21.607  45.152  -21.991 0.33  22.242 ? 328 TYR D OH   1 ? 
ATOM   6136 H H    . TYR B 1 160 ? 17.286  48.864  -18.229 0.33  20.164 ? 328 TYR D H    1 c 
ATOM   6137 H HA   . TYR B 1 160 ? 17.249  50.695  -20.182 0.33  21.424 ? 328 TYR D HA   1 c 
ATOM   6138 H HB2  . TYR B 1 160 ? 19.429  50.538  -20.31  0.33  21     ? 328 TYR D HB2  1 c 
ATOM   6139 H HB3  . TYR B 1 160 ? 19.242  49.804  -18.914 0.33  21     ? 328 TYR D HB3  1 c 
ATOM   6140 H HD1  . TYR B 1 160 ? 19.568  47.361  -18.77  0.33  20.48  ? 328 TYR D HD1  1 c 
ATOM   6141 H HD2  . TYR B 1 160 ? 20.141  49.25   -22.276 0.33  20.975 ? 328 TYR D HD2  1 c 
ATOM   6142 H HE1  . TYR B 1 160 ? 20.61   45.471  -19.619 0.33  20.479 ? 328 TYR D HE1  1 c 
ATOM   6143 H HE2  . TYR B 1 160 ? 21.181  47.362  -23.125 0.33  21.262 ? 328 TYR D HE2  1 c 
ATOM   6144 N N    . GLU B 1 161 ? 16.797  47.72   -21.258 0.33  24.4   ? 329 GLU D N    1 ? 
ATOM   6145 C CA   . GLU B 1 161 ? 16.557  46.918  -22.453 0.33  25.704 ? 329 GLU D CA   1 ? 
ATOM   6146 C C    . GLU B 1 161 ? 15.076  46.596  -22.635 0.33  26.198 ? 329 GLU D C    1 ? 
ATOM   6147 O O    . GLU B 1 161 ? 14.7    46.042  -23.672 0.33  27.243 ? 329 GLU D O    1 ? 
ATOM   6148 C CB   . GLU B 1 161 ? 17.382  45.628  -22.49  0.33  27.919 ? 329 GLU D CB   1 ? 
ATOM   6149 C CG   . GLU B 1 161 ? 16.908  44.558  -21.509 0.33  30.94  ? 329 GLU D CG   1 ? 
ATOM   6150 C CD   . GLU B 1 161 ? 17.585  43.211  -21.631 0.33  32.579 ? 329 GLU D CD   1 ? 
ATOM   6151 O OE1  . GLU B 1 161 ? 18.321  43      -22.616 0.33  38.047 ? 329 GLU D OE1  1 ? 
ATOM   6152 O OE2  . GLU B 1 161 ? 17.398  42.388  -20.709 0.33  32.245 ? 329 GLU D OE2  1 ? 
ATOM   6153 H H    . GLU B 1 161 ? 16.688  47.341  -20.434 0.33  24.401 ? 329 GLU D H    1 c 
ATOM   6154 H HA   . GLU B 1 161 ? 16.841  47.459  -23.233 0.33  25.928 ? 329 GLU D HA   1 c 
ATOM   6155 H HB2  . GLU B 1 161 ? 17.35   45.26   -23.397 0.33  28.049 ? 329 GLU D HB2  1 c 
ATOM   6156 H HB3  . GLU B 1 161 ? 18.317  45.846  -22.29  0.33  28.049 ? 329 GLU D HB3  1 c 
ATOM   6157 H HG2  . GLU B 1 161 ? 17.043  44.888  -20.595 0.33  30.589 ? 329 GLU D HG2  1 c 
ATOM   6158 H HG3  . GLU B 1 161 ? 15.943  44.428  -21.629 0.33  30.589 ? 329 GLU D HG3  1 c 
ATOM   6159 N N    . GLU B 1 162 ? 14.242  46.927  -21.639 0.33  25.725 ? 330 GLU D N    1 ? 
ATOM   6160 C CA   . GLU B 1 162 ? 12.845  46.52   -21.642 0.33  25.337 ? 330 GLU D CA   1 ? 
ATOM   6161 C C    . GLU B 1 162 ? 11.94   47.653  -22.117 0.33  26.503 ? 330 GLU D C    1 ? 
ATOM   6162 O O    . GLU B 1 162 ? 10.746  47.46   -22.338 0.33  28.379 ? 330 GLU D O    1 ? 
ATOM   6163 C CB   . GLU B 1 162 ? 12.44   46.018  -20.259 0.33  23.217 ? 330 GLU D CB   1 ? 
ATOM   6164 C CG   . GLU B 1 162 ? 13.085  44.671  -19.941 0.33  22.066 ? 330 GLU D CG   1 ? 
ATOM   6165 C CD   . GLU B 1 162 ? 12.578  43.938  -18.719 0.33  21.747 ? 330 GLU D CD   1 ? 
ATOM   6166 O OE1  . GLU B 1 162 ? 11.642  44.396  -18.049 0.33  23.589 ? 330 GLU D OE1  1 ? 
ATOM   6167 O OE2  . GLU B 1 162 ? 13.152  42.885  -18.419 0.33  23.781 ? 330 GLU D OE2  1 ? 
ATOM   6168 H H    . GLU B 1 162 ? 14.556  47.421  -20.937 0.33  25.749 ? 330 GLU D H    1 c 
ATOM   6169 H HA   . GLU B 1 162 ? 12.751  45.765  -22.278 0.33  25.214 ? 330 GLU D HA   1 c 
ATOM   6170 H HB2  . GLU B 1 162 ? 12.71   46.678  -19.587 0.33  23.413 ? 330 GLU D HB2  1 c 
ATOM   6171 H HB3  . GLU B 1 162 ? 11.465  45.932  -20.223 0.33  23.413 ? 330 GLU D HB3  1 c 
ATOM   6172 H HG2  . GLU B 1 162 ? 12.969  44.081  -20.717 0.33  22.247 ? 330 GLU D HG2  1 c 
ATOM   6173 H HG3  . GLU B 1 162 ? 14.05   44.808  -19.832 0.33  22.247 ? 330 GLU D HG3  1 c 
ATOM   6174 N N    . ILE B 1 163 ? 12.502  48.852  -22.247 0.33  26.065 ? 331 ILE D N    1 ? 
ATOM   6175 C CA   . ILE B 1 163 ? 11.762  49.978  -22.78  0.33  26.492 ? 331 ILE D CA   1 ? 
ATOM   6176 C C    . ILE B 1 163 ? 12.061  50.084  -24.27  0.33  26.515 ? 331 ILE D C    1 ? 
ATOM   6177 O O    . ILE B 1 163 ? 13.032  49.513  -24.757 0.33  25.576 ? 331 ILE D O    1 ? 
ATOM   6178 C CB   . ILE B 1 163 ? 12.141  51.248  -21.999 0.33  27.044 ? 331 ILE D CB   1 ? 
ATOM   6179 C CG1  . ILE B 1 163 ? 13.625  51.616  -22.202 0.33  27.948 ? 331 ILE D CG1  1 ? 
ATOM   6180 C CG2  . ILE B 1 163 ? 11.78   51.064  -20.519 0.33  27.644 ? 331 ILE D CG2  1 ? 
ATOM   6181 C CD1  . ILE B 1 163 ? 14.099  52.799  -21.367 0.33  26.641 ? 331 ILE D CD1  1 ? 
ATOM   6182 H H    . ILE B 1 163 ? 13.373  48.972  -21.997 0.33  26.265 ? 331 ILE D H    1 c 
ATOM   6183 H HA   . ILE B 1 163 ? 10.807  49.81   -22.66  0.33  26.512 ? 331 ILE D HA   1 c 
ATOM   6184 H HB   . ILE B 1 163 ? 11.602  51.985  -22.35  0.33  27.216 ? 331 ILE D HB   1 c 
ATOM   6185 H HG12 . ILE B 1 163 ? 14.173  50.837  -21.981 0.33  27.439 ? 331 ILE D HG12 1 c 
ATOM   6186 H HG13 . ILE B 1 163 ? 13.769  51.823  -23.148 0.33  27.439 ? 331 ILE D HG13 1 c 
ATOM   6187 H HG21 . ILE B 1 163 ? 12.018  51.866  -20.023 0.33  27.467 ? 331 ILE D HG21 1 c 
ATOM   6188 H HG22 . ILE B 1 163 ? 12.267  50.305  -20.156 0.33  27.467 ? 331 ILE D HG22 1 c 
ATOM   6189 H HG23 . ILE B 1 163 ? 10.825  50.905  -20.433 0.33  27.467 ? 331 ILE D HG23 1 c 
ATOM   6190 H HD11 . ILE B 1 163 ? 13.572  53.59   -21.592 0.33  27.019 ? 331 ILE D HD11 1 c 
ATOM   6191 H HD12 . ILE B 1 163 ? 15.041  52.974  -21.552 0.33  27.019 ? 331 ILE D HD12 1 c 
ATOM   6192 H HD13 . ILE B 1 163 ? 13.988  52.596  -20.419 0.33  27.019 ? 331 ILE D HD13 1 c 
ATOM   6193 N N    . PRO B 1 164 ? 11.25   50.832  -25.045 0.33  29.05  ? 332 PRO D N    1 ? 
ATOM   6194 C CA   . PRO B 1 164 ? 11.552  51.053  -26.459 0.33  29.084 ? 332 PRO D CA   1 ? 
ATOM   6195 C C    . PRO B 1 164 ? 12.943  51.656  -26.63  0.33  30.382 ? 332 PRO D C    1 ? 
ATOM   6196 O O    . PRO B 1 164 ? 13.362  52.504  -25.837 0.33  28.492 ? 332 PRO D O    1 ? 
ATOM   6197 C CB   . PRO B 1 164 ? 10.428  52.004  -26.894 0.33  30.652 ? 332 PRO D CB   1 ? 
ATOM   6198 C CG   . PRO B 1 164 ? 9.29    51.684  -25.944 0.33  29.861 ? 332 PRO D CG   1 ? 
ATOM   6199 C CD   . PRO B 1 164 ? 10.012  51.497  -24.612 0.33  29.617 ? 332 PRO D CD   1 ? 
ATOM   6200 H HA   . PRO B 1 164 ? 11.483  50.198  -26.953 0.33  29.588 ? 332 PRO D HA   1 c 
ATOM   6201 H HB2  . PRO B 1 164 ? 10.708  52.945  -26.804 0.33  30.118 ? 332 PRO D HB2  1 c 
ATOM   6202 H HB3  . PRO B 1 164 ? 10.165  51.835  -27.829 0.33  30.118 ? 332 PRO D HB3  1 c 
ATOM   6203 H HG2  . PRO B 1 164 ? 8.647   52.421  -25.897 0.33  29.982 ? 332 PRO D HG2  1 c 
ATOM   6204 H HG3  . PRO B 1 164 ? 8.824   50.864  -26.211 0.33  29.982 ? 332 PRO D HG3  1 c 
ATOM   6205 H HD2  . PRO B 1 164 ? 10.199  52.362  -24.183 0.33  29.538 ? 332 PRO D HD2  1 c 
ATOM   6206 H HD3  . PRO B 1 164 ? 9.494   50.929  -24.001 0.33  29.538 ? 332 PRO D HD3  1 c 
ATOM   6207 N N    . ALA B 1 165 ? 13.64   51.201  -27.676 0.33  31.035 ? 333 ALA D N    1 ? 
ATOM   6208 C CA   . ALA B 1 165 ? 15.033  51.549  -27.896 0.33  34.001 ? 333 ALA D CA   1 ? 
ATOM   6209 C C    . ALA B 1 165 ? 15.185  53.052  -28.122 0.33  35.328 ? 333 ALA D C    1 ? 
ATOM   6210 O O    . ALA B 1 165 ? 16.259  53.594  -27.89  0.33  34.967 ? 333 ALA D O    1 ? 
ATOM   6211 C CB   . ALA B 1 165 ? 15.586  50.742  -29.053 0.33  34.828 ? 333 ALA D CB   1 ? 
ATOM   6212 H H    . ALA B 1 165 ? 13.227  50.65   -28.277 0.33  31.522 ? 333 ALA D H    1 c 
ATOM   6213 H HA   . ALA B 1 165 ? 15.54   51.312  -27.071 0.33  33.784 ? 333 ALA D HA   1 c 
ATOM   6214 H HB1  . ALA B 1 165 ? 15.523  49.794  -28.85  0.33  34.581 ? 333 ALA D HB1  1 c 
ATOM   6215 H HB2  . ALA B 1 165 ? 15.075  50.932  -29.858 0.33  34.581 ? 333 ALA D HB2  1 c 
ATOM   6216 H HB3  . ALA B 1 165 ? 16.517  50.978  -29.201 0.33  34.581 ? 333 ALA D HB3  1 c 
ATOM   6217 N N    . ASN B 1 166 ? 14.097  53.732  -28.505 0.33  35.787 ? 334 ASN D N    1 ? 
ATOM   6218 C CA   . ASN B 1 166 ? 14.157  55.153  -28.823 0.33  36.043 ? 334 ASN D CA   1 ? 
ATOM   6219 C C    . ASN B 1 166 ? 13.674  56.019  -27.655 0.33  35.674 ? 334 ASN D C    1 ? 
ATOM   6220 O O    . ASN B 1 166 ? 13.407  57.207  -27.833 0.33  33.501 ? 334 ASN D O    1 ? 
ATOM   6221 C CB   . ASN B 1 166 ? 13.375  55.459  -30.1   0.33  36.295 ? 334 ASN D CB   1 ? 
ATOM   6222 C CG   . ASN B 1 166 ? 11.886  55.256  -29.938 0.33  36.365 ? 334 ASN D CG   1 ? 
ATOM   6223 O OD1  . ASN B 1 166 ? 11.404  54.987  -28.833 0.33  36.285 ? 334 ASN D OD1  1 ? 
ATOM   6224 N ND2  . ASN B 1 166 ? 11.135  55.403  -31.019 0.33  37.026 ? 334 ASN D ND2  1 ? 
ATOM   6225 H H    . ASN B 1 166 ? 13.295  53.298  -28.57  0.33  35.734 ? 334 ASN D H    1 c 
ATOM   6226 H HA   . ASN B 1 166 ? 15.098  55.381  -28.999 0.33  35.972 ? 334 ASN D HA   1 c 
ATOM   6227 H HB2  . ASN B 1 166 ? 13.543  56.385  -30.364 0.33  36.254 ? 334 ASN D HB2  1 c 
ATOM   6228 H HB3  . ASN B 1 166 ? 13.698  54.879  -30.819 0.33  36.254 ? 334 ASN D HB3  1 c 
ATOM   6229 H HD21 . ASN B 1 166 ? 10.256  55.294  -30.965 0.33  36.822 ? 334 ASN D HD21 1 c 
ATOM   6230 H HD22 . ASN B 1 166 ? 11.511  55.61   -31.795 0.33  36.822 ? 334 ASN D HD22 1 c 
ATOM   6231 N N    . SER B 1 167 ? 13.617  55.453  -26.442 0.33  34.423 ? 335 SER D N    1 ? 
ATOM   6232 C CA   . SER B 1 167 ? 12.953  56.115  -25.328 0.33  33.711 ? 335 SER D CA   1 ? 
ATOM   6233 C C    . SER B 1 167 ? 13.636  57.425  -24.95  0.33  31.191 ? 335 SER D C    1 ? 
ATOM   6234 O O    . SER B 1 167 ? 12.982  58.301  -24.398 0.33  31.357 ? 335 SER D O    1 ? 
ATOM   6235 C CB   . SER B 1 167 ? 12.878  55.225  -24.121 0.33  34.626 ? 335 SER D CB   1 ? 
ATOM   6236 O OG   . SER B 1 167 ? 12.078  54.082  -24.381 0.33  36.584 ? 335 SER D OG   1 ? 
ATOM   6237 H H    . SER B 1 167 ? 14.001  54.635  -26.307 0.33  34.555 ? 335 SER D H    1 c 
ATOM   6238 H HA   . SER B 1 167 ? 12.027  56.326  -25.612 0.33  33.536 ? 335 SER D HA   1 c 
ATOM   6239 H HB2  . SER B 1 167 ? 13.778  54.943  -23.872 0.33  34.869 ? 335 SER D HB2  1 c 
ATOM   6240 H HB3  . SER B 1 167 ? 12.497  55.726  -23.375 0.33  34.869 ? 335 SER D HB3  1 c 
ATOM   6241 N N    . ALA B 1 168 ? 14.95   57.518  -25.168 0.33  32.427 ? 336 ALA D N    1 ? 
ATOM   6242 C CA   . ALA B 1 168 ? 15.705  58.725  -24.857 0.33  32.73  ? 336 ALA D CA   1 ? 
ATOM   6243 C C    . ALA B 1 168 ? 16.019  59.502  -26.138 0.33  34.556 ? 336 ALA D C    1 ? 
ATOM   6244 O O    . ALA B 1 168 ? 16.891  60.371  -26.143 0.33  31.564 ? 336 ALA D O    1 ? 
ATOM   6245 C CB   . ALA B 1 168 ? 16.982  58.358  -24.124 0.33  32.306 ? 336 ALA D CB   1 ? 
ATOM   6246 H H    . ALA B 1 168 ? 15.394  56.803  -25.525 0.33  32.195 ? 336 ALA D H    1 c 
ATOM   6247 H HA   . ALA B 1 168 ? 15.144  59.303  -24.27  0.33  32.918 ? 336 ALA D HA   1 c 
ATOM   6248 H HB1  . ALA B 1 168 ? 16.763  57.895  -23.298 0.33  32.431 ? 336 ALA D HB1  1 c 
ATOM   6249 H HB2  . ALA B 1 168 ? 17.524  57.776  -24.683 0.33  32.431 ? 336 ALA D HB2  1 c 
ATOM   6250 H HB3  . ALA B 1 168 ? 17.484  59.164  -23.917 0.33  32.431 ? 336 ALA D HB3  1 c 
ATOM   6251 N N    . GLY B 1 169 ? 15.308  59.169  -27.225 0.33  35.625 ? 337 GLY D N    1 ? 
ATOM   6252 C CA   . GLY B 1 169 ? 15.583  59.731  -28.54  0.33  34.056 ? 337 GLY D CA   1 ? 
ATOM   6253 C C    . GLY B 1 169 ? 16.934  59.274  -29.094 0.33  33.779 ? 337 GLY D C    1 ? 
ATOM   6254 O O    . GLY B 1 169 ? 17.502  59.946  -29.955 0.33  35.291 ? 337 GLY D O    1 ? 
ATOM   6255 H H    . GLY B 1 169 ? 14.626  58.568  -27.141 0.33  35.01  ? 337 GLY D H    1 c 
ATOM   6256 H HA2  . GLY B 1 169 ? 14.866  59.461  -29.16  0.33  34.361 ? 337 GLY D HA2  1 c 
ATOM   6257 H HA3  . GLY B 1 169 ? 15.572  60.715  -28.476 0.33  34.361 ? 337 GLY D HA3  1 c 
ATOM   6258 N N    . THR B 1 170 ? 17.449  58.136  -28.6   0.33  31.181 ? 338 THR D N    1 ? 
ATOM   6259 C CA   . THR B 1 170 ? 18.728  57.616  -29.053 0.33  31.263 ? 338 THR D CA   1 ? 
ATOM   6260 C C    . THR B 1 170 ? 18.551  56.163  -29.493 0.33  31.869 ? 338 THR D C    1 ? 
ATOM   6261 O O    . THR B 1 170 ? 17.763  55.891  -30.394 0.33  30.066 ? 338 THR D O    1 ? 
ATOM   6262 C CB   . THR B 1 170 ? 19.773  57.804  -27.95  0.33  32.161 ? 338 THR D CB   1 ? 
ATOM   6263 O OG1  . THR B 1 170 ? 19.305  57.162  -26.767 0.33  32.038 ? 338 THR D OG1  1 ? 
ATOM   6264 C CG2  . THR B 1 170 ? 19.983  59.272  -27.62  0.33  30.877 ? 338 THR D CG2  1 ? 
ATOM   6265 H H    . THR B 1 170 ? 16.986  57.673  -27.963 0.33  31.801 ? 338 THR D H    1 c 
ATOM   6266 H HA   . THR B 1 170 ? 19.009  58.142  -29.833 0.33  31.521 ? 338 THR D HA   1 c 
ATOM   6267 H HB   . THR B 1 170 ? 20.63   57.401  -28.227 0.33  31.736 ? 338 THR D HB   1 c 
ATOM   6268 H HG21 . THR B 1 170 ? 20.65   59.354  -26.918 0.33  31.251 ? 338 THR D HG21 1 c 
ATOM   6269 H HG22 . THR B 1 170 ? 19.145  59.66   -27.317 0.33  31.251 ? 338 THR D HG22 1 c 
ATOM   6270 H HG23 . THR B 1 170 ? 20.289  59.743  -28.414 0.33  31.251 ? 338 THR D HG23 1 c 
ATOM   6271 N N    . ASN B 1 171 ? 19.289  55.235  -28.87  0.33  32.23  ? 339 ASN D N    1 ? 
ATOM   6272 C CA   . ASN B 1 171 ? 19.19   53.826  -29.215 0.33  33.019 ? 339 ASN D CA   1 ? 
ATOM   6273 C C    . ASN B 1 171 ? 19.514  52.96   -27.998 0.33  32.585 ? 339 ASN D C    1 ? 
ATOM   6274 O O    . ASN B 1 171 ? 19.772  53.471  -26.907 0.33  33.119 ? 339 ASN D O    1 ? 
ATOM   6275 C CB   . ASN B 1 171 ? 20.048  53.496  -30.43  0.33  32.707 ? 339 ASN D CB   1 ? 
ATOM   6276 C CG   . ASN B 1 171 ? 21.527  53.644  -30.179 0.33  32.926 ? 339 ASN D CG   1 ? 
ATOM   6277 O OD1  . ASN B 1 171 ? 21.957  53.929  -29.055 0.33  31.164 ? 339 ASN D OD1  1 ? 
ATOM   6278 N ND2  . ASN B 1 171 ? 22.321  53.364  -31.203 0.33  33.669 ? 339 ASN D ND2  1 ? 
ATOM   6279 H H    . ASN B 1 171 ? 19.87   55.49   -28.211 0.33  32.319 ? 339 ASN D H    1 c 
ATOM   6280 H HA   . ASN B 1 171 ? 18.256  53.648  -29.467 0.33  32.727 ? 339 ASN D HA   1 c 
ATOM   6281 H HB2  . ASN B 1 171 ? 19.865  52.575  -30.706 0.33  32.828 ? 339 ASN D HB2  1 c 
ATOM   6282 H HB3  . ASN B 1 171 ? 19.792  54.084  -31.168 0.33  32.828 ? 339 ASN D HB3  1 c 
ATOM   6283 H HD21 . ASN B 1 171 ? 23.2    53.44   -31.114 0.33  33.438 ? 339 ASN D HD21 1 c 
ATOM   6284 H HD22 . ASN B 1 171 ? 21.972  53.101  -31.975 0.33  33.438 ? 339 ASN D HD22 1 c 
ATOM   6285 N N    . ARG B 1 172 ? 19.498  51.641  -28.207 0.33  31.185 ? 340 ARG D N    1 ? 
ATOM   6286 C CA   . ARG B 1 172 ? 19.646  50.69   -27.118 0.33  28.729 ? 340 ARG D CA   1 ? 
ATOM   6287 C C    . ARG B 1 172 ? 21.013  50.858  -26.465 0.33  27.658 ? 340 ARG D C    1 ? 
ATOM   6288 O O    . ARG B 1 172 ? 21.108  50.782  -25.245 0.33  26.002 ? 340 ARG D O    1 ? 
ATOM   6289 C CB   . ARG B 1 172 ? 19.481  49.237  -27.581 0.33  27.016 ? 340 ARG D CB   1 ? 
ATOM   6290 C CG   . ARG B 1 172 ? 19.594  48.204  -26.463 0.33  25.916 ? 340 ARG D CG   1 ? 
ATOM   6291 C CD   . ARG B 1 172 ? 18.492  48.324  -25.418 0.33  24.825 ? 340 ARG D CD   1 ? 
ATOM   6292 N NE   . ARG B 1 172 ? 17.204  47.896  -25.966 0.33  24.203 ? 340 ARG D NE   1 ? 
ATOM   6293 C CZ   . ARG B 1 172 ? 16.028  48.48   -25.793 0.33  24.053 ? 340 ARG D CZ   1 ? 
ATOM   6294 N NH1  . ARG B 1 172 ? 15.847  49.431  -24.897 0.33  26.384 ? 340 ARG D NH1  1 ? 
ATOM   6295 N NH2  . ARG B 1 172 ? 15.004  48.063  -26.507 0.33  25.094 ? 340 ARG D NH2  1 ? 
ATOM   6296 H H    . ARG B 1 172 ? 19.391  51.324  -29.057 0.33  30.935 ? 340 ARG D H    1 c 
ATOM   6297 H HA   . ARG B 1 172 ? 18.95   50.885  -26.441 0.33  28.668 ? 340 ARG D HA   1 c 
ATOM   6298 H HB2  . ARG B 1 172 ? 18.604  49.143  -28.009 0.33  27.137 ? 340 ARG D HB2  1 c 
ATOM   6299 H HB3  . ARG B 1 172 ? 20.165  49.044  -28.257 0.33  27.137 ? 340 ARG D HB3  1 c 
ATOM   6300 H HG2  . ARG B 1 172 ? 19.562  47.304  -26.855 0.33  25.906 ? 340 ARG D HG2  1 c 
ATOM   6301 H HG3  . ARG B 1 172 ? 20.464  48.305  -26.02  0.33  25.906 ? 340 ARG D HG3  1 c 
ATOM   6302 H HD2  . ARG B 1 172 ? 18.715  47.769  -24.643 0.33  24.915 ? 340 ARG D HD2  1 c 
ATOM   6303 H HD3  . ARG B 1 172 ? 18.424  49.253  -25.119 0.33  24.915 ? 340 ARG D HD3  1 c 
ATOM   6304 H HE   . ARG B 1 172 ? 17.206  47.18   -26.461 0.33  24.311 ? 340 ARG D HE   1 c 
ATOM   6305 H HH11 . ARG B 1 172 ? 16.523  49.69   -24.391 0.33  25.643 ? 340 ARG D HH11 1 c 
ATOM   6306 H HH12 . ARG B 1 172 ? 15.051  49.804  -24.808 0.33  25.643 ? 340 ARG D HH12 1 c 
ATOM   6307 H HH21 . ARG B 1 172 ? 15.112  47.407  -27.09  0.33  24.769 ? 340 ARG D HH21 1 c 
ATOM   6308 H HH22 . ARG B 1 172 ? 14.212  48.441  -26.4   0.33  24.769 ? 340 ARG D HH22 1 c 
ATOM   6309 N N    . ALA B 1 173 ? 22.06   51.068  -27.281 0.33  27.048 ? 341 ALA D N    1 ? 
ATOM   6310 C CA   . ALA B 1 173 ? 23.42   51.136  -26.773 0.33  25.711 ? 341 ALA D CA   1 ? 
ATOM   6311 C C    . ALA B 1 173 ? 23.553  52.35   -25.86  0.33  25.689 ? 341 ALA D C    1 ? 
ATOM   6312 O O    . ALA B 1 173 ? 24.254  52.287  -24.851 0.33  26.908 ? 341 ALA D O    1 ? 
ATOM   6313 C CB   . ALA B 1 173 ? 24.43   51.165  -27.905 0.33  25.001 ? 341 ALA D CB   1 ? 
ATOM   6314 H H    . ALA B 1 173 ? 21.917  51.171  -28.178 0.33  26.883 ? 341 ALA D H    1 c 
ATOM   6315 H HA   . ALA B 1 173 ? 23.581  50.321  -26.223 0.33  25.83  ? 341 ALA D HA   1 c 
ATOM   6316 H HB1  . ALA B 1 173 ? 24.347  50.357  -28.439 0.33  25.209 ? 341 ALA D HB1  1 c 
ATOM   6317 H HB2  . ALA B 1 173 ? 24.268  51.94   -28.469 0.33  25.209 ? 341 ALA D HB2  1 c 
ATOM   6318 H HB3  . ALA B 1 173 ? 25.33   51.217  -27.54  0.33  25.209 ? 341 ALA D HB3  1 c 
ATOM   6319 N N    . ASP B 1 174 ? 22.848  53.436  -26.202 0.33  23.713 ? 342 ASP D N    1 ? 
ATOM   6320 C CA   . ASP B 1 174 ? 22.907  54.662  -25.424 0.33  22.294 ? 342 ASP D CA   1 ? 
ATOM   6321 C C    . ASP B 1 174 ? 22.148  54.468  -24.114 0.33  22.556 ? 342 ASP D C    1 ? 
ATOM   6322 O O    . ASP B 1 174 ? 22.577  54.972  -23.08  0.33  24.66  ? 342 ASP D O    1 ? 
ATOM   6323 C CB   . ASP B 1 174 ? 22.391  55.88   -26.183 0.33  21.703 ? 342 ASP D CB   1 ? 
ATOM   6324 C CG   . ASP B 1 174 ? 22.433  57.172  -25.381 0.33  20.956 ? 342 ASP D CG   1 ? 
ATOM   6325 O OD1  . ASP B 1 174 ? 23.546  57.62   -25.064 0.33  21.769 ? 342 ASP D OD1  1 ? 
ATOM   6326 O OD2  . ASP B 1 174 ? 21.353  57.679  -25.012 0.33  22.368 ? 342 ASP D OD2  1 ? 
ATOM   6327 H H    . ASP B 1 174 ? 22.314  53.409  -26.944 0.33  23.836 ? 342 ASP D H    1 c 
ATOM   6328 H HA   . ASP B 1 174 ? 23.851  54.837  -25.208 0.33  22.498 ? 342 ASP D HA   1 c 
ATOM   6329 H HB2  . ASP B 1 174 ? 22.93   56.001  -26.993 0.33  21.661 ? 342 ASP D HB2  1 c 
ATOM   6330 H HB3  . ASP B 1 174 ? 21.464  55.715  -26.456 0.33  21.661 ? 342 ASP D HB3  1 c 
ATOM   6331 N N    . LEU B 1 175 ? 21.022  53.744  -24.169 0.33  22.326 ? 343 LEU D N    1 ? 
ATOM   6332 C CA   . LEU B 1 175 ? 20.264  53.428  -22.967 0.33  22.688 ? 343 LEU D CA   1 ? 
ATOM   6333 C C    . LEU B 1 175 ? 21.135  52.595  -22.029 0.33  19.782 ? 343 LEU D C    1 ? 
ATOM   6334 O O    . LEU B 1 175 ? 21.091  52.805  -20.814 0.33  17.842 ? 343 LEU D O    1 ? 
ATOM   6335 C CB   . LEU B 1 175 ? 18.937  52.736  -23.279 0.33  23.39  ? 343 LEU D CB   1 ? 
ATOM   6336 C CG   . LEU B 1 175 ? 17.906  53.595  -24.018 0.33  24.364 ? 343 LEU D CG   1 ? 
ATOM   6337 C CD1  . LEU B 1 175 ? 16.711  52.769  -24.495 0.33  25.891 ? 343 LEU D CD1  1 ? 
ATOM   6338 C CD2  . LEU B 1 175 ? 17.459  54.761  -23.145 0.33  23.891 ? 343 LEU D CD2  1 ? 
ATOM   6339 H H    . LEU B 1 175 ? 20.72   53.44   -24.976 0.33  22.462 ? 343 LEU D H    1 c 
ATOM   6340 H HA   . LEU B 1 175 ? 20.067  54.284  -22.508 0.33  22.174 ? 343 LEU D HA   1 c 
ATOM   6341 H HB2  . LEU B 1 175 ? 19.127  51.938  -23.826 0.33  23.444 ? 343 LEU D HB2  1 c 
ATOM   6342 H HB3  . LEU B 1 175 ? 18.54   52.433  -22.43  0.33  23.444 ? 343 LEU D HB3  1 c 
ATOM   6343 H HG   . LEU B 1 175 ? 18.348  53.975  -24.821 0.33  24.366 ? 343 LEU D HG   1 c 
ATOM   6344 H HD11 . LEU B 1 175 ? 17.019  52.067  -25.093 0.33  25.433 ? 343 LEU D HD11 1 c 
ATOM   6345 H HD12 . LEU B 1 175 ? 16.086  53.344  -24.967 0.33  25.433 ? 343 LEU D HD12 1 c 
ATOM   6346 H HD13 . LEU B 1 175 ? 16.267  52.368  -23.729 0.33  25.433 ? 343 LEU D HD13 1 c 
ATOM   6347 H HD21 . LEU B 1 175 ? 18.227  55.312  -22.919 0.33  24.029 ? 343 LEU D HD21 1 c 
ATOM   6348 H HD22 . LEU B 1 175 ? 17.056  54.42   -22.329 0.33  24.029 ? 343 LEU D HD22 1 c 
ATOM   6349 H HD23 . LEU B 1 175 ? 16.808  55.297  -23.628 0.33  24.029 ? 343 LEU D HD23 1 c 
ATOM   6350 N N    . ALA B 1 176 ? 21.912  51.665  -22.597 0.33  18.728 ? 344 ALA D N    1 ? 
ATOM   6351 C CA   . ALA B 1 176 ? 22.851  50.865  -21.824 0.33  20.422 ? 344 ALA D CA   1 ? 
ATOM   6352 C C    . ALA B 1 176 ? 23.877  51.76   -21.133 0.33  21.059 ? 344 ALA D C    1 ? 
ATOM   6353 O O    . ALA B 1 176 ? 24.136  51.601  -19.944 0.33  23.51  ? 344 ALA D O    1 ? 
ATOM   6354 C CB   . ALA B 1 176 ? 23.526  49.834  -22.694 0.33  20.433 ? 344 ALA D CB   1 ? 
ATOM   6355 H H    . ALA B 1 176 ? 21.854  51.525  -23.499 0.33  19.348 ? 344 ALA D H    1 c 
ATOM   6356 H HA   . ALA B 1 176 ? 22.334  50.393  -21.114 0.33  20.196 ? 344 ALA D HA   1 c 
ATOM   6357 H HB1  . ALA B 1 176 ? 22.857  49.246  -23.083 0.33  20.43  ? 344 ALA D HB1  1 c 
ATOM   6358 H HB2  . ALA B 1 176 ? 24.016  50.278  -23.406 0.33  20.43  ? 344 ALA D HB2  1 c 
ATOM   6359 H HB3  . ALA B 1 176 ? 24.143  49.308  -22.159 0.33  20.43  ? 344 ALA D HB3  1 c 
ATOM   6360 N N    . ARG B 1 177 ? 24.47   52.7    -21.881 0.33  21.798 ? 345 ARG D N    1 ? 
ATOM   6361 C CA   . ARG B 1 177 ? 25.478  53.59   -21.323 0.33  22.807 ? 345 ARG D CA   1 ? 
ATOM   6362 C C    . ARG B 1 177 ? 24.862  54.411  -20.197 0.33  20.13  ? 345 ARG D C    1 ? 
ATOM   6363 O O    . ARG B 1 177 ? 25.496  54.633  -19.169 0.33  19.414 ? 345 ARG D O    1 ? 
ATOM   6364 C CB   . ARG B 1 177 ? 26.102  54.478  -22.412 0.33  25.642 ? 345 ARG D CB   1 ? 
ATOM   6365 C CG   . ARG B 1 177 ? 26.921  53.688  -23.424 0.33  29.181 ? 345 ARG D CG   1 ? 
ATOM   6366 C CD   . ARG B 1 177 ? 27.748  54.547  -24.376 0.33  31.265 ? 345 ARG D CD   1 ? 
ATOM   6367 N NE   . ARG B 1 177 ? 26.957  55.65   -24.938 0.33  33.447 ? 345 ARG D NE   1 ? 
ATOM   6368 C CZ   . ARG B 1 177 ? 26.394  55.68   -26.147 0.33  34.583 ? 345 ARG D CZ   1 ? 
ATOM   6369 N NH1  . ARG B 1 177 ? 26.473  54.638  -26.96  0.33  33.92  ? 345 ARG D NH1  1 ? 
ATOM   6370 N NH2  . ARG B 1 177 ? 25.723  56.757  -26.526 0.33  35.481 ? 345 ARG D NH2  1 ? 
ATOM   6371 H H    . ARG B 1 177 ? 24.241  52.787  -22.761 0.33  21.84  ? 345 ARG D H    1 c 
ATOM   6372 H HA   . ARG B 1 177 ? 26.198  53.029  -20.937 0.33  22.57  ? 345 ARG D HA   1 c 
ATOM   6373 H HB2  . ARG B 1 177 ? 25.387  54.955  -22.883 0.33  25.722 ? 345 ARG D HB2  1 c 
ATOM   6374 H HB3  . ARG B 1 177 ? 26.681  55.146  -21.986 0.33  25.722 ? 345 ARG D HB3  1 c 
ATOM   6375 H HG2  . ARG B 1 177 ? 27.525  53.084  -22.941 0.33  28.781 ? 345 ARG D HG2  1 c 
ATOM   6376 H HG3  . ARG B 1 177 ? 26.313  53.128  -23.955 0.33  28.781 ? 345 ARG D HG3  1 c 
ATOM   6377 H HD2  . ARG B 1 177 ? 28.517  54.914  -23.894 0.33  31.279 ? 345 ARG D HD2  1 c 
ATOM   6378 H HD3  . ARG B 1 177 ? 28.086  53.988  -25.105 0.33  31.279 ? 345 ARG D HD3  1 c 
ATOM   6379 H HE   . ARG B 1 177 ? 26.843  56.354  -24.438 0.33  33.19  ? 345 ARG D HE   1 c 
ATOM   6380 H HH11 . ARG B 1 177 ? 26.905  53.911  -26.701 0.33  34.123 ? 345 ARG D HH11 1 c 
ATOM   6381 H HH12 . ARG B 1 177 ? 26.095  54.674  -27.758 0.33  34.123 ? 345 ARG D HH12 1 c 
ATOM   6382 H HH21 . ARG B 1 177 ? 25.658  57.449  -25.981 0.33  35.202 ? 345 ARG D HH21 1 c 
ATOM   6383 H HH22 . ARG B 1 177 ? 25.343  56.778  -27.324 0.33  35.202 ? 345 ARG D HH22 1 c 
ATOM   6384 N N    . LYS B 1 178 ? 23.611  54.841  -20.378 0.33  18.282 ? 346 LYS D N    1 ? 
ATOM   6385 C CA   . LYS B 1 178 ? 22.947  55.664  -19.385 0.33  17.498 ? 346 LYS D CA   1 ? 
ATOM   6386 C C    . LYS B 1 178 ? 22.695  54.885  -18.094 0.33  16.387 ? 346 LYS D C    1 ? 
ATOM   6387 O O    . LYS B 1 178 ? 22.743  55.468  -17.014 0.33  16.193 ? 346 LYS D O    1 ? 
ATOM   6388 C CB   . LYS B 1 178 ? 21.627  56.206  -19.932 0.33  17.073 ? 346 LYS D CB   1 ? 
ATOM   6389 C CG   . LYS B 1 178 ? 21.78   57.379  -20.896 0.33  17.303 ? 346 LYS D CG   1 ? 
ATOM   6390 C CD   . LYS B 1 178 ? 20.476  57.725  -21.602 0.33  17.86  ? 346 LYS D CD   1 ? 
ATOM   6391 C CE   . LYS B 1 178 ? 20.363  59.167  -22.042 0.33  18.771 ? 346 LYS D CE   1 ? 
ATOM   6392 N NZ   . LYS B 1 178 ? 21.395  59.516  -23.01  0.33  19.384 ? 346 LYS D NZ   1 ? 
ATOM   6393 H H    . LYS B 1 178 ? 23.16   54.614  -21.14  0.33  18.523 ? 346 LYS D H    1 c 
ATOM   6394 H HA   . LYS B 1 178 ? 23.539  56.432  -19.177 0.33  17.36  ? 346 LYS D HA   1 c 
ATOM   6395 H HB2  . LYS B 1 178 ? 21.157  55.481  -20.397 0.33  17.221 ? 346 LYS D HB2  1 c 
ATOM   6396 H HB3  . LYS B 1 178 ? 21.067  56.492  -19.18  0.33  17.221 ? 346 LYS D HB3  1 c 
ATOM   6397 H HG2  . LYS B 1 178 ? 22.094  58.163  -20.393 0.33  17.375 ? 346 LYS D HG2  1 c 
ATOM   6398 H HG3  . LYS B 1 178 ? 22.461  57.152  -21.566 0.33  17.375 ? 346 LYS D HG3  1 c 
ATOM   6399 H HD2  . LYS B 1 178 ? 20.385  57.147  -22.391 0.33  17.936 ? 346 LYS D HD2  1 c 
ATOM   6400 H HD3  . LYS B 1 178 ? 19.73   57.52   -20.999 0.33  17.936 ? 346 LYS D HD3  1 c 
ATOM   6401 H HE2  . LYS B 1 178 ? 19.489  59.317  -22.443 0.33  18.704 ? 346 LYS D HE2  1 c 
ATOM   6402 H HE3  . LYS B 1 178 ? 20.446  59.751  -21.267 0.33  18.704 ? 346 LYS D HE3  1 c 
ATOM   6403 H HZ1  . LYS B 1 178 ? 21.327  58.979  -23.737 0.33  19.193 ? 346 LYS D HZ1  1 c 
ATOM   6404 H HZ2  . LYS B 1 178 ? 22.214  59.409  -22.636 0.33  19.193 ? 346 LYS D HZ2  1 c 
ATOM   6405 H HZ3  . LYS B 1 178 ? 21.295  60.379  -23.266 0.33  19.193 ? 346 LYS D HZ3  1 c 
ATOM   6406 N N    . MET B 1 179 ? 22.393  53.589  -18.211 0.33  15.766 ? 347 MET D N    1 ? 
ATOM   6407 C CA   . MET B 1 179 ? 22.126  52.785  -17.028 0.33  16.049 ? 347 MET D CA   1 ? 
ATOM   6408 C C    . MET B 1 179 ? 23.426  52.566  -16.261 0.33  15.526 ? 347 MET D C    1 ? 
ATOM   6409 O O    . MET B 1 179 ? 23.444  52.642  -15.03  0.33  15.983 ? 347 MET D O    1 ? 
ATOM   6410 C CB   . MET B 1 179 ? 21.482  51.445  -17.397 0.33  15.839 ? 347 MET D CB   1 ? 
ATOM   6411 C CG   . MET B 1 179 ? 21.241  50.525  -16.206 0.33  16.202 ? 347 MET D CG   1 ? 
ATOM   6412 S SD   . MET B 1 179 ? 20.175  51.241  -14.944 0.33  15.781 ? 347 MET D SD   1 ? 
ATOM   6413 C CE   . MET B 1 179 ? 18.576  51.396  -15.744 0.33  16.424 ? 347 MET D CE   1 ? 
ATOM   6414 H H    . MET B 1 179 ? 22.352  53.2    -19.037 0.33  15.975 ? 347 MET D H    1 c 
ATOM   6415 H HA   . MET B 1 179 ? 21.505  53.294  -16.446 0.33  15.858 ? 347 MET D HA   1 c 
ATOM   6416 H HB2  . MET B 1 179 ? 20.625  51.621  -17.841 0.33  15.969 ? 347 MET D HB2  1 c 
ATOM   6417 H HB3  . MET B 1 179 ? 22.062  50.986  -18.041 0.33  15.969 ? 347 MET D HB3  1 c 
ATOM   6418 H HG2  . MET B 1 179 ? 20.835  49.693  -16.521 0.33  16.034 ? 347 MET D HG2  1 c 
ATOM   6419 H HG3  . MET B 1 179 ? 22.1    50.3    -15.797 0.33  16.034 ? 347 MET D HG3  1 c 
ATOM   6420 H HE1  . MET B 1 179 ? 17.94   51.795  -15.122 0.33  16.261 ? 347 MET D HE1  1 c 
ATOM   6421 H HE2  . MET B 1 179 ? 18.661  51.963  -16.532 0.33  16.261 ? 347 MET D HE2  1 c 
ATOM   6422 H HE3  . MET B 1 179 ? 18.26   50.513  -16.011 0.33  16.261 ? 347 MET D HE3  1 c 
ATOM   6423 N N    . VAL B 1 180 ? 24.514  52.309  -16.988 0.33  15.665 ? 348 VAL D N    1 ? 
ATOM   6424 C CA   . VAL B 1 180 ? 25.811  52.14   -16.356 0.33  16.027 ? 348 VAL D CA   1 ? 
ATOM   6425 C C    . VAL B 1 180 ? 26.232  53.455  -15.701 0.33  15.736 ? 348 VAL D C    1 ? 
ATOM   6426 O O    . VAL B 1 180 ? 26.793  53.446  -14.608 0.33  15.862 ? 348 VAL D O    1 ? 
ATOM   6427 C CB   . VAL B 1 180 ? 26.842  51.627  -17.376 0.33  16.563 ? 348 VAL D CB   1 ? 
ATOM   6428 C CG1  . VAL B 1 180 ? 28.267  51.693  -16.848 0.33  17.393 ? 348 VAL D CG1  1 ? 
ATOM   6429 C CG2  . VAL B 1 180 ? 26.504  50.212  -17.818 0.33  16.711 ? 348 VAL D CG2  1 ? 
ATOM   6430 H H    . VAL B 1 180 ? 24.448  52.236  -17.897 0.33  15.713 ? 348 VAL D H    1 c 
ATOM   6431 H HA   . VAL B 1 180 ? 25.718  51.467  -15.654 0.33  15.998 ? 348 VAL D HA   1 c 
ATOM   6432 H HB   . VAL B 1 180 ? 26.785  52.213  -18.167 0.33  16.641 ? 348 VAL D HB   1 c 
ATOM   6433 H HG11 . VAL B 1 180 ? 28.344  51.141  -16.052 0.33  17.144 ? 348 VAL D HG11 1 c 
ATOM   6434 H HG12 . VAL B 1 180 ? 28.488  52.613  -16.625 0.33  17.144 ? 348 VAL D HG12 1 c 
ATOM   6435 H HG13 . VAL B 1 180 ? 28.881  51.369  -17.528 0.33  17.144 ? 348 VAL D HG13 1 c 
ATOM   6436 H HG21 . VAL B 1 180 ? 27.164  49.907  -18.463 0.33  16.667 ? 348 VAL D HG21 1 c 
ATOM   6437 H HG22 . VAL B 1 180 ? 25.623  50.201  -18.228 0.33  16.667 ? 348 VAL D HG22 1 c 
ATOM   6438 H HG23 . VAL B 1 180 ? 26.508  49.621  -17.046 0.33  16.667 ? 348 VAL D HG23 1 c 
ATOM   6439 N N    . ALA B 1 181 ? 25.956  54.587  -16.365 0.33  14.837 ? 349 ALA D N    1 ? 
ATOM   6440 C CA   . ALA B 1 181 ? 26.286  55.89   -15.806 0.33  15.213 ? 349 ALA D CA   1 ? 
ATOM   6441 C C    . ALA B 1 181 ? 25.521  56.138  -14.502 0.33  14.728 ? 349 ALA D C    1 ? 
ATOM   6442 O O    . ALA B 1 181 ? 26.05   56.726  -13.563 0.33  13.824 ? 349 ALA D O    1 ? 
ATOM   6443 C CB   . ALA B 1 181 ? 26.005  56.958  -16.834 0.33  15.97  ? 349 ALA D CB   1 ? 
ATOM   6444 H H    . ALA B 1 181 ? 25.554  54.544  -17.184 0.33  15.132 ? 349 ALA D H    1 c 
ATOM   6445 H HA   . ALA B 1 181 ? 27.261  55.895  -15.595 0.33  15.185 ? 349 ALA D HA   1 c 
ATOM   6446 H HB1  . ALA B 1 181 ? 26.538  56.794  -17.63  0.33  15.741 ? 349 ALA D HB1  1 c 
ATOM   6447 H HB2  . ALA B 1 181 ? 25.062  56.944  -17.07  0.33  15.741 ? 349 ALA D HB2  1 c 
ATOM   6448 H HB3  . ALA B 1 181 ? 26.231  57.83   -16.47  0.33  15.741 ? 349 ALA D HB3  1 c 
ATOM   6449 N N    . LEU B 1 182 ? 24.272  55.674  -14.426 0.33  14.175 ? 350 LEU D N    1 ? 
ATOM   6450 C CA   . LEU B 1 182 ? 23.485  55.86   -13.221 0.33  14.921 ? 350 LEU D CA   1 ? 
ATOM   6451 C C    . LEU B 1 182 ? 24.061  55.018  -12.082 0.33  14.144 ? 350 LEU D C    1 ? 
ATOM   6452 O O    . LEU B 1 182 ? 24.157  55.494  -10.948 0.33  14.965 ? 350 LEU D O    1 ? 
ATOM   6453 C CB   . LEU B 1 182 ? 22.016  55.531  -13.477 0.33  15.639 ? 350 LEU D CB   1 ? 
ATOM   6454 C CG   . LEU B 1 182 ? 21.102  55.601  -12.252 0.33  15.582 ? 350 LEU D CG   1 ? 
ATOM   6455 C CD1  . LEU B 1 182 ? 21.102  56.959  -11.57  0.33  15.13  ? 350 LEU D CD1  1 ? 
ATOM   6456 C CD2  . LEU B 1 182 ? 19.7    55.214  -12.649 0.33  16.486 ? 350 LEU D CD2  1 ? 
ATOM   6457 H H    . LEU B 1 182 ? 23.904  55.233  -15.137 0.33  14.471 ? 350 LEU D H    1 c 
ATOM   6458 H HA   . LEU B 1 182 ? 23.555  56.814  -12.96  0.33  14.754 ? 350 LEU D HA   1 c 
ATOM   6459 H HB2  . LEU B 1 182 ? 21.675  56.157  -14.157 0.33  15.459 ? 350 LEU D HB2  1 c 
ATOM   6460 H HB3  . LEU B 1 182 ? 21.966  54.621  -13.852 0.33  15.459 ? 350 LEU D HB3  1 c 
ATOM   6461 H HG   . LEU B 1 182 ? 21.424  54.933  -11.593 0.33  15.672 ? 350 LEU D HG   1 c 
ATOM   6462 H HD11 . LEU B 1 182 ? 22.004  57.177  -11.279 0.33  15.262 ? 350 LEU D HD11 1 c 
ATOM   6463 H HD12 . LEU B 1 182 ? 20.511  56.936  -10.798 0.33  15.262 ? 350 LEU D HD12 1 c 
ATOM   6464 H HD13 . LEU B 1 182 ? 20.792  57.637  -12.194 0.33  15.262 ? 350 LEU D HD13 1 c 
ATOM   6465 H HD21 . LEU B 1 182 ? 19.7    54.308  -13.002 0.33  16.211 ? 350 LEU D HD21 1 c 
ATOM   6466 H HD22 . LEU B 1 182 ? 19.374  55.825  -13.331 0.33  16.211 ? 350 LEU D HD22 1 c 
ATOM   6467 H HD23 . LEU B 1 182 ? 19.118  55.257  -11.872 0.33  16.211 ? 350 LEU D HD23 1 c 
ATOM   6468 N N    . ILE B 1 183 ? 24.433  53.769  -12.375 0.33  13.346 ? 351 ILE D N    1 ? 
ATOM   6469 C CA   . ILE B 1 183 ? 25.061  52.907  -11.388 0.33  13.091 ? 351 ILE D CA   1 ? 
ATOM   6470 C C    . ILE B 1 183 ? 26.364  53.555  -10.901 0.33  11.92  ? 351 ILE D C    1 ? 
ATOM   6471 O O    . ILE B 1 183 ? 26.668  53.557  -9.722  0.33  11.208 ? 351 ILE D O    1 ? 
ATOM   6472 C CB   . ILE B 1 183 ? 25.267  51.498  -11.992 0.33  13.612 ? 351 ILE D CB   1 ? 
ATOM   6473 C CG1  . ILE B 1 183 ? 23.918  50.805  -12.221 0.33  13.351 ? 351 ILE D CG1  1 ? 
ATOM   6474 C CG2  . ILE B 1 183 ? 26.211  50.641  -11.151 0.33  14.163 ? 351 ILE D CG2  1 ? 
ATOM   6475 C CD1  . ILE B 1 183 ? 23.975  49.551  -13.086 0.33  14.113 ? 351 ILE D CD1  1 ? 
ATOM   6476 H H    . ILE B 1 183 ? 24.291  53.444  -13.218 0.33  13.473 ? 351 ILE D H    1 c 
ATOM   6477 H HA   . ILE B 1 183 ? 24.455  52.825  -10.626 0.33  13.008 ? 351 ILE D HA   1 c 
ATOM   6478 H HB   . ILE B 1 183 ? 25.684  51.617  -12.869 0.33  13.566 ? 351 ILE D HB   1 c 
ATOM   6479 H HG12 . ILE B 1 183 ? 23.541  50.565  -11.35  0.33  13.581 ? 351 ILE D HG12 1 c 
ATOM   6480 H HG13 . ILE B 1 183 ? 23.308  51.445  -12.641 0.33  13.581 ? 351 ILE D HG13 1 c 
ATOM   6481 H HG21 . ILE B 1 183 ? 26.312  49.767  -11.563 0.33  13.999 ? 351 ILE D HG21 1 c 
ATOM   6482 H HG22 . ILE B 1 183 ? 25.846  50.535  -10.256 0.33  13.999 ? 351 ILE D HG22 1 c 
ATOM   6483 H HG23 . ILE B 1 183 ? 27.08   51.073  -11.095 0.33  13.999 ? 351 ILE D HG23 1 c 
ATOM   6484 H HD11 . ILE B 1 183 ? 24.32   49.78   -13.971 0.33  13.885 ? 351 ILE D HD11 1 c 
ATOM   6485 H HD12 . ILE B 1 183 ? 23.08   49.174  -13.176 0.33  13.885 ? 351 ILE D HD12 1 c 
ATOM   6486 H HD13 . ILE B 1 183 ? 24.564  48.893  -12.67  0.33  13.885 ? 351 ILE D HD13 1 c 
ATOM   6487 N N    . ALA B 1 184 ? 27.147  54.128  -11.814 0.33  11.361 ? 352 ALA D N    1 ? 
ATOM   6488 C CA   . ALA B 1 184 ? 28.395  54.77   -11.435 0.33  11.484 ? 352 ALA D CA   1 ? 
ATOM   6489 C C    . ALA B 1 184 ? 28.093  56.028  -10.614 0.33  12.058 ? 352 ALA D C    1 ? 
ATOM   6490 O O    . ALA B 1 184 ? 28.835  56.377  -9.723  0.33  12.655 ? 352 ALA D O    1 ? 
ATOM   6491 C CB   . ALA B 1 184 ? 29.186  55.098  -12.683 0.33  11.569 ? 352 ALA D CB   1 ? 
ATOM   6492 H H    . ALA B 1 184 ? 26.9    54.12   -12.694 0.33  11.52  ? 352 ALA D H    1 c 
ATOM   6493 H HA   . ALA B 1 184 ? 28.917  54.138  -10.867 0.33  11.578 ? 352 ALA D HA   1 c 
ATOM   6494 H HB1  . ALA B 1 184 ? 29.377  54.281  -13.173 0.33  11.544 ? 352 ALA D HB1  1 c 
ATOM   6495 H HB2  . ALA B 1 184 ? 28.67   55.698  -13.249 0.33  11.544 ? 352 ALA D HB2  1 c 
ATOM   6496 H HB3  . ALA B 1 184 ? 30.022  55.528  -12.438 0.33  11.544 ? 352 ALA D HB3  1 c 
ATOM   6497 N N    . ARG B 1 185 ? 26.999  56.729  -10.911 0.33  12.834 ? 353 ARG D N    1 ? 
ATOM   6498 C CA   . ARG B 1 185 ? 26.653  57.938  -10.176 0.33  13.506 ? 353 ARG D CA   1 ? 
ATOM   6499 C C    . ARG B 1 185 ? 26.261  57.548  -8.747  0.33  13.059 ? 353 ARG D C    1 ? 
ATOM   6500 O O    . ARG B 1 185 ? 26.612  58.219  -7.778  0.33  12.676 ? 353 ARG D O    1 ? 
ATOM   6501 C CB   . ARG B 1 185 ? 25.545  58.73   -10.883 0.33  14.494 ? 353 ARG D CB   1 ? 
ATOM   6502 C CG   . ARG B 1 185 ? 25.225  60.047  -10.185 0.33  15.189 ? 353 ARG D CG   1 ? 
ATOM   6503 C CD   . ARG B 1 185 ? 24.049  60.763  -10.801 0.33  16.359 ? 353 ARG D CD   1 ? 
ATOM   6504 N NE   . ARG B 1 185 ? 23.871  62.077  -10.182 0.33  16.532 ? 353 ARG D NE   1 ? 
ATOM   6505 C CZ   . ARG B 1 185 ? 23.091  63.025  -10.66  0.33  16.721 ? 353 ARG D CZ   1 ? 
ATOM   6506 N NH1  . ARG B 1 185 ? 22.251  62.758  -11.639 0.33  15.822 ? 353 ARG D NH1  1 ? 
ATOM   6507 N NH2  . ARG B 1 185 ? 23.188  64.233  -10.152 0.33  16.49  ? 353 ARG D NH2  1 ? 
ATOM   6508 H H    . ARG B 1 185 ? 26.453  56.45   -11.589 0.33  12.79  ? 353 ARG D H    1 c 
ATOM   6509 H HA   . ARG B 1 185 ? 27.46   58.51   -10.13  0.33  13.462 ? 353 ARG D HA   1 c 
ATOM   6510 H HB2  . ARG B 1 185 ? 25.823  58.917  -11.805 0.33  14.418 ? 353 ARG D HB2  1 c 
ATOM   6511 H HB3  . ARG B 1 185 ? 24.732  58.182  -10.919 0.33  14.418 ? 353 ARG D HB3  1 c 
ATOM   6512 H HG2  . ARG B 1 185 ? 25.031  59.871  -9.238  0.33  15.288 ? 353 ARG D HG2  1 c 
ATOM   6513 H HG3  . ARG B 1 185 ? 26.012  60.633  -10.226 0.33  15.288 ? 353 ARG D HG3  1 c 
ATOM   6514 H HD2  . ARG B 1 185 ? 24.197  60.874  -11.762 0.33  16.127 ? 353 ARG D HD2  1 c 
ATOM   6515 H HD3  . ARG B 1 185 ? 23.236  60.232  -10.674 0.33  16.127 ? 353 ARG D HD3  1 c 
ATOM   6516 H HE   . ARG B 1 185 ? 24.309  62.246  -9.448  0.33  16.536 ? 353 ARG D HE   1 c 
ATOM   6517 H HH11 . ARG B 1 185 ? 22.204  61.938  -11.966 0.33  16.094 ? 353 ARG D HH11 1 c 
ATOM   6518 H HH12 . ARG B 1 185 ? 21.738  63.4    -11.964 0.33  16.094 ? 353 ARG D HH12 1 c 
ATOM   6519 H HH21 . ARG B 1 185 ? 23.922  64.705  -10.285 0.33  16.561 ? 353 ARG D HH21 1 c 
ATOM   6520 H HH22 . ARG B 1 185 ? 22.518  64.566  -9.683  0.33  16.561 ? 353 ARG D HH22 1 c 
ATOM   6521 N N    . ILE B 1 186 ? 25.551  56.43   -8.616  0.33  12.945 ? 354 ILE D N    1 ? 
ATOM   6522 C CA   . ILE B 1 186 ? 25.144  55.96   -7.302  0.33  12.737 ? 354 ILE D CA   1 ? 
ATOM   6523 C C    . ILE B 1 186 ? 26.404  55.633  -6.502  0.33  12.385 ? 354 ILE D C    1 ? 
ATOM   6524 O O    . ILE B 1 186 ? 26.552  56.015  -5.346  0.33  12.567 ? 354 ILE D O    1 ? 
ATOM   6525 C CB   . ILE B 1 186 ? 24.228  54.729  -7.45   0.33  12.911 ? 354 ILE D CB   1 ? 
ATOM   6526 C CG1  . ILE B 1 186 ? 22.823  55.115  -7.954  0.33  13.233 ? 354 ILE D CG1  1 ? 
ATOM   6527 C CG2  . ILE B 1 186 ? 24.184  53.96   -6.122  0.33  12.672 ? 354 ILE D CG2  1 ? 
ATOM   6528 C CD1  . ILE B 1 186 ? 21.987  53.945  -8.453  0.33  13.379 ? 354 ILE D CD1  1 ? 
ATOM   6529 H H    . ILE B 1 186 ? 25.315  55.949  -9.356  0.33  12.925 ? 354 ILE D H    1 c 
ATOM   6530 H HA   . ILE B 1 186 ? 24.651  56.671  -6.848  0.33  12.744 ? 354 ILE D HA   1 c 
ATOM   6531 H HB   . ILE B 1 186 ? 24.63   54.141  -8.121  0.33  12.893 ? 354 ILE D HB   1 c 
ATOM   6532 H HG12 . ILE B 1 186 ? 22.34   55.556  -7.225  0.33  13.193 ? 354 ILE D HG12 1 c 
ATOM   6533 H HG13 . ILE B 1 186 ? 22.92   55.763  -8.682  0.33  13.193 ? 354 ILE D HG13 1 c 
ATOM   6534 H HG21 . ILE B 1 186 ? 23.605  53.184  -6.214  0.33  12.741 ? 354 ILE D HG21 1 c 
ATOM   6535 H HG22 . ILE B 1 186 ? 23.837  54.539  -5.422  0.33  12.741 ? 354 ILE D HG22 1 c 
ATOM   6536 H HG23 . ILE B 1 186 ? 25.08   53.668  -5.884  0.33  12.741 ? 354 ILE D HG23 1 c 
ATOM   6537 H HD11 . ILE B 1 186 ? 22.451  53.501  -9.188  0.33  13.336 ? 354 ILE D HD11 1 c 
ATOM   6538 H HD12 . ILE B 1 186 ? 21.122  54.271  -8.766  0.33  13.336 ? 354 ILE D HD12 1 c 
ATOM   6539 H HD13 . ILE B 1 186 ? 21.849  53.308  -7.726  0.33  13.336 ? 354 ILE D HD13 1 c 
ATOM   6540 N N    . ASN B 1 187 ? 27.296  54.877  -7.133  0.33  12.151 ? 355 ASN D N    1 ? 
ATOM   6541 C CA   . ASN B 1 187 ? 28.536  54.456  -6.497  0.33  12.582 ? 355 ASN D CA   1 ? 
ATOM   6542 C C    . ASN B 1 187 ? 29.352  55.653  -6.006  0.33  11.901 ? 355 ASN D C    1 ? 
ATOM   6543 O O    . ASN B 1 187 ? 29.859  55.643  -4.893  0.33  11.656 ? 355 ASN D O    1 ? 
ATOM   6544 C CB   . ASN B 1 187 ? 29.33   53.559  -7.435  0.33  12.349 ? 355 ASN D CB   1 ? 
ATOM   6545 C CG   . ASN B 1 187 ? 30.601  53.076  -6.802  0.33  13.652 ? 355 ASN D CG   1 ? 
ATOM   6546 O OD1  . ASN B 1 187 ? 30.567  52.294  -5.843  0.33  15.372 ? 355 ASN D OD1  1 ? 
ATOM   6547 N ND2  . ASN B 1 187 ? 31.72   53.519  -7.351  0.33  14.843 ? 355 ASN D ND2  1 ? 
ATOM   6548 H H    . ASN B 1 187 ? 27.13   54.612  -7.991  0.33  12.303 ? 355 ASN D H    1 c 
ATOM   6549 H HA   . ASN B 1 187 ? 28.298  53.913  -5.712  0.33  12.327 ? 355 ASN D HA   1 c 
ATOM   6550 H HB2  . ASN B 1 187 ? 28.782  52.788  -7.684  0.33  12.692 ? 355 ASN D HB2  1 c 
ATOM   6551 H HB3  . ASN B 1 187 ? 29.544  54.055  -8.25   0.33  12.692 ? 355 ASN D HB3  1 c 
ATOM   6552 H HD21 . ASN B 1 187 ? 32.505  53.267  -7.022  0.33  14.466 ? 355 ASN D HD21 1 c 
ATOM   6553 H HD22 . ASN B 1 187 ? 31.685  54.068  -8.047  0.33  14.466 ? 355 ASN D HD22 1 c 
ATOM   6554 N N    . THR B 1 188 ? 29.551  56.655  -6.867  0.33  11.914 ? 356 THR D N    1 ? 
ATOM   6555 C CA   . THR B 1 188 ? 30.41   57.775  -6.524  0.33  11.719 ? 356 THR D CA   1 ? 
ATOM   6556 C C    . THR B 1 188 ? 29.795  58.584  -5.384  0.33  11.922 ? 356 THR D C    1 ? 
ATOM   6557 O O    . THR B 1 188 ? 30.486  58.994  -4.442  0.33  11.008 ? 356 THR D O    1 ? 
ATOM   6558 C CB   . THR B 1 188 ? 30.588  58.61   -7.79   0.33  11.383 ? 356 THR D CB   1 ? 
ATOM   6559 O OG1  . THR B 1 188 ? 31.311  57.791  -8.693  0.33  10.472 ? 356 THR D OG1  1 ? 
ATOM   6560 C CG2  . THR B 1 188 ? 31.261  59.927  -7.502  0.33  11.35  ? 356 THR D CG2  1 ? 
ATOM   6561 H H    . THR B 1 188 ? 29.143  56.641  -7.685  0.33  11.866 ? 356 THR D H    1 c 
ATOM   6562 H HA   . THR B 1 188 ? 31.285  57.43   -6.242  0.33  11.731 ? 356 THR D HA   1 c 
ATOM   6563 H HB   . THR B 1 188 ? 29.698  58.799  -8.173  0.33  11.253 ? 356 THR D HB   1 c 
ATOM   6564 H HG21 . THR B 1 188 ? 31.188  60.494  -8.283  0.33  11.36  ? 356 THR D HG21 1 c 
ATOM   6565 H HG22 . THR B 1 188 ? 32.199  59.777  -7.294  0.33  11.36  ? 356 THR D HG22 1 c 
ATOM   6566 H HG23 . THR B 1 188 ? 30.825  60.356  -6.748  0.33  11.36  ? 356 THR D HG23 1 c 
ATOM   6567 N N    . TYR B 1 189 ? 28.474  58.794  -5.467  0.33  11.754 ? 357 TYR D N    1 ? 
ATOM   6568 C CA   . TYR B 1 189 ? 27.75   59.524  -4.443  0.33  12.04  ? 357 TYR D CA   1 ? 
ATOM   6569 C C    . TYR B 1 189 ? 27.872  58.804  -3.098  0.33  12.635 ? 357 TYR D C    1 ? 
ATOM   6570 O O    . TYR B 1 189 ? 28.129  59.426  -2.075  0.33  11.699 ? 357 TYR D O    1 ? 
ATOM   6571 C CB   . TYR B 1 189 ? 26.287  59.723  -4.845  0.33  12.637 ? 357 TYR D CB   1 ? 
ATOM   6572 C CG   . TYR B 1 189 ? 25.462  60.443  -3.792  0.33  12.913 ? 357 TYR D CG   1 ? 
ATOM   6573 C CD1  . TYR B 1 189 ? 24.848  59.734  -2.766  0.33  12.785 ? 357 TYR D CD1  1 ? 
ATOM   6574 C CD2  . TYR B 1 189 ? 25.3    61.827  -3.804  0.33  12.792 ? 357 TYR D CD2  1 ? 
ATOM   6575 C CE1  . TYR B 1 189 ? 24.071  60.372  -1.812  0.33  13.308 ? 357 TYR D CE1  1 ? 
ATOM   6576 C CE2  . TYR B 1 189 ? 24.532  62.472  -2.85   0.33  13.218 ? 357 TYR D CE2  1 ? 
ATOM   6577 C CZ   . TYR B 1 189 ? 23.93   61.748  -1.832  0.33  14.018 ? 357 TYR D CZ   1 ? 
ATOM   6578 O OH   . TYR B 1 189 ? 23.191  62.372  -0.87   0.33  13.476 ? 357 TYR D OH   1 ? 
ATOM   6579 H H    . TYR B 1 189 ? 28.013  58.47   -6.187  0.33  11.858 ? 357 TYR D H    1 c 
ATOM   6580 H HA   . TYR B 1 189 ? 28.169  60.421  -4.352  0.33  12.197 ? 357 TYR D HA   1 c 
ATOM   6581 H HB2  . TYR B 1 189 ? 26.26   60.239  -5.681  0.33  12.561 ? 357 TYR D HB2  1 c 
ATOM   6582 H HB3  . TYR B 1 189 ? 25.887  58.841  -5.018  0.33  12.56  ? 357 TYR D HB3  1 c 
ATOM   6583 H HD1  . TYR B 1 189 ? 24.935  58.794  -2.736  0.33  12.942 ? 357 TYR D HD1  1 c 
ATOM   6584 H HD2  . TYR B 1 189 ? 25.707  62.334  -4.489  0.33  12.927 ? 357 TYR D HD2  1 c 
ATOM   6585 H HE1  . TYR B 1 189 ? 23.671  59.872  -1.121  0.33  13.337 ? 357 TYR D HE1  1 c 
ATOM   6586 H HE2  . TYR B 1 189 ? 24.443  63.41   -2.873  0.33  13.291 ? 357 TYR D HE2  1 c 
ATOM   6587 N N    . ALA B 1 190 ? 27.634  57.492  -3.101  0.33  13.125 ? 358 ALA D N    1 ? 
ATOM   6588 C CA   . ALA B 1 190 ? 27.611  56.733  -1.864  0.33  13.088 ? 358 ALA D CA   1 ? 
ATOM   6589 C C    . ALA B 1 190 ? 29.014  56.618  -1.259  0.33  13.644 ? 358 ALA D C    1 ? 
ATOM   6590 O O    . ALA B 1 190 ? 29.192  56.768  -0.056  0.33  15.087 ? 358 ALA D O    1 ? 
ATOM   6591 C CB   . ALA B 1 190 ? 27.039  55.364  -2.123  0.33  13.58  ? 358 ALA D CB   1 ? 
ATOM   6592 H H    . ALA B 1 190 ? 27.483  57.06   -3.892  0.33  12.998 ? 358 ALA D H    1 c 
ATOM   6593 H HA   . ALA B 1 190 ? 27.029  57.213  -1.213  0.33  13.284 ? 358 ALA D HA   1 c 
ATOM   6594 H HB1  . ALA B 1 190 ? 26.131  55.448  -2.459  0.33  13.431 ? 358 ALA D HB1  1 c 
ATOM   6595 H HB2  . ALA B 1 190 ? 27.583  54.902  -2.783  0.33  13.431 ? 358 ALA D HB2  1 c 
ATOM   6596 H HB3  . ALA B 1 190 ? 27.031  54.851  -1.298  0.33  13.431 ? 358 ALA D HB3  1 c 
ATOM   6597 N N    . LYS B 1 191 ? 30.011  56.323  -2.091  0.33  13.625 ? 359 LYS D N    1 ? 
ATOM   6598 C CA   . LYS B 1 191 ? 31.349  56.092  -1.567  0.33  14.662 ? 359 LYS D CA   1 ? 
ATOM   6599 C C    . LYS B 1 191 ? 31.947  57.395  -1.025  0.33  15.564 ? 359 LYS D C    1 ? 
ATOM   6600 O O    . LYS B 1 191 ? 32.804  57.366  -0.137  0.33  13.283 ? 359 LYS D O    1 ? 
ATOM   6601 C CB   . LYS B 1 191 ? 32.234  55.359  -2.572  0.33  15.501 ? 359 LYS D CB   1 ? 
ATOM   6602 C CG   . LYS B 1 191 ? 31.976  53.85   -2.632  0.33  16.604 ? 359 LYS D CG   1 ? 
ATOM   6603 C CD   . LYS B 1 191 ? 32.829  53.112  -3.655  0.33  16.468 ? 359 LYS D CD   1 ? 
ATOM   6604 C CE   . LYS B 1 191 ? 32.789  51.624  -3.448  0.33  16.037 ? 359 LYS D CE   1 ? 
ATOM   6605 N NZ   . LYS B 1 191 ? 31.461  51.048  -3.656  0.33  16.208 ? 359 LYS D NZ   1 ? 
ATOM   6606 H H    . LYS B 1 191 ? 29.862  56.265  -2.991  0.33  13.855 ? 359 LYS D H    1 c 
ATOM   6607 H HA   . LYS B 1 191 ? 31.253  55.478  -0.795  0.33  14.768 ? 359 LYS D HA   1 c 
ATOM   6608 H HB2  . LYS B 1 191 ? 32.086  55.739  -3.464  0.33  15.547 ? 359 LYS D HB2  1 c 
ATOM   6609 H HB3  . LYS B 1 191 ? 33.175  55.507  -2.335  0.33  15.547 ? 359 LYS D HB3  1 c 
ATOM   6610 H HG2  . LYS B 1 191 ? 32.144  53.469  -1.743  0.33  16.316 ? 359 LYS D HG2  1 c 
ATOM   6611 H HG3  . LYS B 1 191 ? 31.028  53.705  -2.845  0.33  16.316 ? 359 LYS D HG3  1 c 
ATOM   6612 H HD2  . LYS B 1 191 ? 32.504  53.32   -4.558  0.33  16.398 ? 359 LYS D HD2  1 c 
ATOM   6613 H HD3  . LYS B 1 191 ? 33.758  53.422  -3.584  0.33  16.398 ? 359 LYS D HD3  1 c 
ATOM   6614 H HE2  . LYS B 1 191 ? 33.414  51.2    -4.063  0.33  16.175 ? 359 LYS D HE2  1 c 
ATOM   6615 H HE3  . LYS B 1 191 ? 33.08   51.421  -2.541  0.33  16.175 ? 359 LYS D HE3  1 c 
ATOM   6616 H HZ1  . LYS B 1 191 ? 31.181  51.22   -4.5    0.33  16.156 ? 359 LYS D HZ1  1 c 
ATOM   6617 H HZ2  . LYS B 1 191 ? 30.875  51.41   -3.068  0.33  16.156 ? 359 LYS D HZ2  1 c 
ATOM   6618 H HZ3  . LYS B 1 191 ? 31.494  50.151  -3.53   0.33  16.156 ? 359 LYS D HZ3  1 c 
ATOM   6619 N N    . ALA B 1 192 ? 31.452  58.541  -1.496  0.33  15.356 ? 360 ALA D N    1 ? 
ATOM   6620 C CA   . ALA B 1 192 ? 31.892  59.808  -0.94   0.33  17.064 ? 360 ALA D CA   1 ? 
ATOM   6621 C C    . ALA B 1 192 ? 31.48   59.93   0.53    0.33  17.762 ? 360 ALA D C    1 ? 
ATOM   6622 O O    . ALA B 1 192 ? 32.16   60.583  1.315   0.33  18.863 ? 360 ALA D O    1 ? 
ATOM   6623 C CB   . ALA B 1 192 ? 31.349  60.936  -1.788  0.33  18.487 ? 360 ALA D CB   1 ? 
ATOM   6624 H H    . ALA B 1 192 ? 30.834  58.535  -2.17   0.33  15.775 ? 360 ALA D H    1 c 
ATOM   6625 H HA   . ALA B 1 192 ? 32.888  59.829  -0.98   0.33  17.088 ? 360 ALA D HA   1 c 
ATOM   6626 H HB1  . ALA B 1 192 ? 31.678  60.849  -2.698  0.33  18.053 ? 360 ALA D HB1  1 c 
ATOM   6627 H HB2  . ALA B 1 192 ? 30.377  60.903  -1.794  0.33  18.053 ? 360 ALA D HB2  1 c 
ATOM   6628 H HB3  . ALA B 1 192 ? 31.638  61.789  -1.422  0.33  18.053 ? 360 ALA D HB3  1 c 
ATOM   6629 N N    . ARG B 1 193 ? 30.378  59.278  0.906   0.33  18.173 ? 361 ARG D N    1 ? 
ATOM   6630 C CA   . ARG B 1 193 ? 29.877  59.296  2.272   0.33  19.558 ? 361 ARG D CA   1 ? 
ATOM   6631 C C    . ARG B 1 193 ? 30.433  58.134  3.092   0.33  20.347 ? 361 ARG D C    1 ? 
ATOM   6632 O O    . ARG B 1 193 ? 30.636  58.272  4.294   0.33  22.044 ? 361 ARG D O    1 ? 
ATOM   6633 C CB   . ARG B 1 193 ? 28.349  59.225  2.255   0.33  19.684 ? 361 ARG D CB   1 ? 
ATOM   6634 C CG   . ARG B 1 193 ? 27.832  60.506  1.625   0.33  19.964 ? 361 ARG D CG   1 ? 
ATOM   6635 C CD   . ARG B 1 193 ? 26.526  60.469  0.897   0.33  19.582 ? 361 ARG D CD   1 ? 
ATOM   6636 N NE   . ARG B 1 193 ? 26.134  61.867  0.663   0.33  18.557 ? 361 ARG D NE   1 ? 
ATOM   6637 C CZ   . ARG B 1 193 ? 26.636  62.672  -0.252  0.33  18.359 ? 361 ARG D CZ   1 ? 
ATOM   6638 N NH1  . ARG B 1 193 ? 27.543  62.249  -1.13   0.33  17.86  ? 361 ARG D NH1  1 ? 
ATOM   6639 N NH2  . ARG B 1 193 ? 26.168  63.898  -0.309  0.33  18.664 ? 361 ARG D NH2  1 ? 
ATOM   6640 H H    . ARG B 1 193 ? 29.917  58.798  0.28    0.33  18.377 ? 361 ARG D H    1 c 
ATOM   6641 H HA   . ARG B 1 193 ? 30.156  60.148  2.696   0.33  19.442 ? 361 ARG D HA   1 c 
ATOM   6642 H HB2  . ARG B 1 193 ? 28.052  58.451  1.73    0.33  19.719 ? 361 ARG D HB2  1 c 
ATOM   6643 H HB3  . ARG B 1 193 ? 28.003  59.139  3.169   0.33  19.719 ? 361 ARG D HB3  1 c 
ATOM   6644 H HG2  . ARG B 1 193 ? 27.764  61.185  2.332   0.33  19.81  ? 361 ARG D HG2  1 c 
ATOM   6645 H HG3  . ARG B 1 193 ? 28.516  60.834  1.001   0.33  19.81  ? 361 ARG D HG3  1 c 
ATOM   6646 H HD2  . ARG B 1 193 ? 26.62   60.003  0.041   0.33  19.422 ? 361 ARG D HD2  1 c 
ATOM   6647 H HD3  . ARG B 1 193 ? 25.843  60.018  1.433   0.33  19.422 ? 361 ARG D HD3  1 c 
ATOM   6648 H HE   . ARG B 1 193 ? 25.513  62.199  1.176   0.33  18.742 ? 361 ARG D HE   1 c 
ATOM   6649 H HH11 . ARG B 1 193 ? 27.816  61.409  -1.109  0.33  18.012 ? 361 ARG D HH11 1 c 
ATOM   6650 H HH12 . ARG B 1 193 ? 27.868  62.811  -1.73   0.33  18.012 ? 361 ARG D HH12 1 c 
ATOM   6651 H HH21 . ARG B 1 193 ? 25.369  64.077  0.024   0.33  18.57  ? 361 ARG D HH21 1 c 
ATOM   6652 H HH22 . ARG B 1 193 ? 26.652  64.534  -0.687  0.33  18.57  ? 361 ARG D HH22 1 c 
ATOM   6653 N N    . ASN B 1 194 ? 30.636  56.986  2.439   0.33  18.88  ? 362 ASN D N    1 ? 
ATOM   6654 C CA   . ASN B 1 194 ? 31.141  55.79   3.085   0.33  18.615 ? 362 ASN D CA   1 ? 
ATOM   6655 C C    . ASN B 1 194 ? 31.914  54.994  2.054   0.33  17.441 ? 362 ASN D C    1 ? 
ATOM   6656 O O    . ASN B 1 194 ? 31.309  54.422  1.166   0.33  15.978 ? 362 ASN D O    1 ? 
ATOM   6657 C CB   . ASN B 1 194 ? 30.02   54.938  3.674   0.33  18.567 ? 362 ASN D CB   1 ? 
ATOM   6658 C CG   . ASN B 1 194 ? 30.523  53.654  4.299   0.33  19.563 ? 362 ASN D CG   1 ? 
ATOM   6659 O OD1  . ASN B 1 194 ? 31.731  53.381  4.317   0.33  19.592 ? 362 ASN D OD1  1 ? 
ATOM   6660 N ND2  . ASN B 1 194 ? 29.611  52.841  4.814   0.33  20.512 ? 362 ASN D ND2  1 ? 
ATOM   6661 H H    . ASN B 1 194 ? 30.449  56.952  1.545   0.33  19.158 ? 362 ASN D H    1 c 
ATOM   6662 H HA   . ASN B 1 194 ? 31.745  56.052  3.816   0.33  18.436 ? 362 ASN D HA   1 c 
ATOM   6663 H HB2  . ASN B 1 194 ? 29.548  55.459  4.355   0.33  18.802 ? 362 ASN D HB2  1 c 
ATOM   6664 H HB3  . ASN B 1 194 ? 29.381  54.719  2.967   0.33  18.802 ? 362 ASN D HB3  1 c 
ATOM   6665 H HD21 . ASN B 1 194 ? 29.861  52.08   5.195   0.33  20.215 ? 362 ASN D HD21 1 c 
ATOM   6666 H HD22 . ASN B 1 194 ? 28.752  53.06   4.777   0.33  20.215 ? 362 ASN D HD22 1 c 
ATOM   6667 N N    . PRO B 1 195 ? 33.263  54.977  2.08    0.33  17.561 ? 363 PRO D N    1 ? 
ATOM   6668 C CA   . PRO B 1 195 ? 34.005  54.374  0.978   0.33  18.298 ? 363 PRO D CA   1 ? 
ATOM   6669 C C    . PRO B 1 195 ? 33.817  52.863  0.924   0.33  17.628 ? 363 PRO D C    1 ? 
ATOM   6670 O O    . PRO B 1 195 ? 34.164  52.247  -0.077  0.33  18.848 ? 363 PRO D O    1 ? 
ATOM   6671 C CB   . PRO B 1 195 ? 35.469  54.767  1.249   0.33  18.71  ? 363 PRO D CB   1 ? 
ATOM   6672 C CG   . PRO B 1 195 ? 35.5    55.04   2.725   0.33  18.658 ? 363 PRO D CG   1 ? 
ATOM   6673 C CD   . PRO B 1 195 ? 34.129  55.598  3.089   0.33  18.205 ? 363 PRO D CD   1 ? 
ATOM   6674 H HA   . PRO B 1 195 ? 33.704  54.78   0.127   0.33  18.102 ? 363 PRO D HA   1 c 
ATOM   6675 H HB2  . PRO B 1 195 ? 36.082  54.031  1.013   0.33  18.606 ? 363 PRO D HB2  1 c 
ATOM   6676 H HB3  . PRO B 1 195 ? 35.719  55.571  0.736   0.33  18.606 ? 363 PRO D HB3  1 c 
ATOM   6677 H HG2  . PRO B 1 195 ? 35.677  54.215  3.223   0.33  18.567 ? 363 PRO D HG2  1 c 
ATOM   6678 H HG3  . PRO B 1 195 ? 36.202  55.689  2.94    0.33  18.567 ? 363 PRO D HG3  1 c 
ATOM   6679 H HD2  . PRO B 1 195 ? 33.867  55.332  3.998   0.33  18.152 ? 363 PRO D HD2  1 c 
ATOM   6680 H HD3  . PRO B 1 195 ? 34.114  56.579  3.017   0.33  18.152 ? 363 PRO D HD3  1 c 
ATOM   6681 N N    . ASP B 1 196 ? 33.28   52.287  2.007   0.33  18.101 ? 364 ASP D N    1 ? 
ATOM   6682 C CA   . ASP B 1 196 ? 33.061  50.854  2.096   0.33  18.101 ? 364 ASP D CA   1 ? 
ATOM   6683 C C    . ASP B 1 196 ? 31.651  50.454  1.651   0.33  16.918 ? 364 ASP D C    1 ? 
ATOM   6684 O O    . ASP B 1 196 ? 31.299  49.282  1.726   0.33  16.542 ? 364 ASP D O    1 ? 
ATOM   6685 C CB   . ASP B 1 196 ? 33.304  50.366  3.513   0.33  20.099 ? 364 ASP D CB   1 ? 
ATOM   6686 C CG   . ASP B 1 196 ? 34.739  50.527  3.995   0.33  21.85  ? 364 ASP D CG   1 ? 
ATOM   6687 O OD1  . ASP B 1 196 ? 35.658  50.243  3.199   0.33  25.792 ? 364 ASP D OD1  1 ? 
ATOM   6688 O OD2  . ASP B 1 196 ? 34.921  50.918  5.164   0.33  25.632 ? 364 ASP D OD2  1 ? 
ATOM   6689 H H    . ASP B 1 196 ? 33.042  52.812  2.716   0.33  17.987 ? 364 ASP D H    1 c 
ATOM   6690 H HA   . ASP B 1 196 ? 33.712  50.407  1.508   0.33  18.231 ? 364 ASP D HA   1 c 
ATOM   6691 H HB2  . ASP B 1 196 ? 32.717  50.859  4.123   0.33  20.003 ? 364 ASP D HB2  1 c 
ATOM   6692 H HB3  . ASP B 1 196 ? 33.067  49.416  3.566   0.33  20.003 ? 364 ASP D HB3  1 c 
ATOM   6693 N N    . PHE B 1 197 ? 30.831  51.42   1.219   0.33  14.883 ? 365 PHE D N    1 ? 
ATOM   6694 C CA   . PHE B 1 197 ? 29.445  51.145  0.868   0.33  13.93  ? 365 PHE D CA   1 ? 
ATOM   6695 C C    . PHE B 1 197 ? 29.419  50.422  -0.479  0.33  13.212 ? 365 PHE D C    1 ? 
ATOM   6696 O O    . PHE B 1 197 ? 29.858  50.982  -1.49   0.33  13.139 ? 365 PHE D O    1 ? 
ATOM   6697 C CB   . PHE B 1 197 ? 28.665  52.455  0.826   0.33  13.507 ? 365 PHE D CB   1 ? 
ATOM   6698 C CG   . PHE B 1 197 ? 27.162  52.317  0.656   0.33  12.992 ? 365 PHE D CG   1 ? 
ATOM   6699 C CD1  . PHE B 1 197 ? 26.588  52.257  -0.609  0.33  13.466 ? 365 PHE D CD1  1 ? 
ATOM   6700 C CD2  . PHE B 1 197 ? 26.332  52.187  1.773   0.33  13.259 ? 365 PHE D CD2  1 ? 
ATOM   6701 C CE1  . PHE B 1 197 ? 25.21   52.155  -0.75   0.33  13.293 ? 365 PHE D CE1  1 ? 
ATOM   6702 C CE2  . PHE B 1 197 ? 24.958  52.065  1.621   0.33  12.94  ? 365 PHE D CE2  1 ? 
ATOM   6703 C CZ   . PHE B 1 197 ? 24.407  52.051  0.367   0.33  13.397 ? 365 PHE D CZ   1 ? 
ATOM   6704 H H    . PHE B 1 197 ? 31.145  52.274  1.141   0.33  15.119 ? 365 PHE D H    1 c 
ATOM   6705 H HA   . PHE B 1 197 ? 29.048  50.554  1.561   0.33  13.896 ? 365 PHE D HA   1 c 
ATOM   6706 H HB2  . PHE B 1 197 ? 28.843  52.945  1.659   0.33  13.482 ? 365 PHE D HB2  1 c 
ATOM   6707 H HB3  . PHE B 1 197 ? 29.015  52.998  0.085   0.33  13.482 ? 365 PHE D HB3  1 c 
ATOM   6708 H HD1  . PHE B 1 197 ? 27.134  52.349  -1.374  0.33  13.314 ? 365 PHE D HD1  1 c 
ATOM   6709 H HD2  . PHE B 1 197 ? 26.707  52.215  2.638   0.33  13.129 ? 365 PHE D HD2  1 c 
ATOM   6710 H HE1  . PHE B 1 197 ? 24.826  52.129  -1.612  0.33  13.352 ? 365 PHE D HE1  1 c 
ATOM   6711 H HE2  . PHE B 1 197 ? 24.404  51.996  2.382   0.33  13.123 ? 365 PHE D HE2  1 c 
ATOM   6712 H HZ   . PHE B 1 197 ? 23.473  51.954  0.266   0.33  13.264 ? 365 PHE D HZ   1 c 
ATOM   6713 N N    . LYS B 1 198 ? 28.889  49.196  -0.467  0.33  12.567 ? 366 LYS D N    1 ? 
ATOM   6714 C CA   . LYS B 1 198 ? 28.945  48.291  -1.604  0.33  12.841 ? 366 LYS D CA   1 ? 
ATOM   6715 C C    . LYS B 1 198 ? 27.799  48.571  -2.568  0.33  12.225 ? 366 LYS D C    1 ? 
ATOM   6716 O O    . LYS B 1 198 ? 26.72   48.999  -2.169  0.33  10.927 ? 366 LYS D O    1 ? 
ATOM   6717 C CB   . LYS B 1 198 ? 28.889  46.832  -1.145  0.33  14.392 ? 366 LYS D CB   1 ? 
ATOM   6718 C CG   . LYS B 1 198 ? 30.049  46.445  -0.256  0.33  16.709 ? 366 LYS D CG   1 ? 
ATOM   6719 C CD   . LYS B 1 198 ? 31.412  46.643  -0.918  0.33  17.969 ? 366 LYS D CD   1 ? 
ATOM   6720 C CE   . LYS B 1 198 ? 32.547  46.103  -0.061  0.33  20.263 ? 366 LYS D CE   1 ? 
ATOM   6721 N NZ   . LYS B 1 198 ? 32.588  46.824  1.215   0.33  18.49  ? 366 LYS D NZ   1 ? 
ATOM   6722 H H    . LYS B 1 198 ? 28.47   48.91   0.294   0.33  12.78  ? 366 LYS D H    1 c 
ATOM   6723 H HA   . LYS B 1 198 ? 29.801  48.443  -2.079  0.33  12.938 ? 366 LYS D HA   1 c 
ATOM   6724 H HB2  . LYS B 1 198 ? 28.053  46.682  -0.654  0.33  14.517 ? 366 LYS D HB2  1 c 
ATOM   6725 H HB3  . LYS B 1 198 ? 28.887  46.248  -1.933  0.33  14.517 ? 366 LYS D HB3  1 c 
ATOM   6726 H HG2  . LYS B 1 198 ? 30.009  46.983  0.564   0.33  16.41  ? 366 LYS D HG2  1 c 
ATOM   6727 H HG3  . LYS B 1 198 ? 29.949  45.502  -0.003  0.33  16.41  ? 366 LYS D HG3  1 c 
ATOM   6728 H HD2  . LYS B 1 198 ? 31.419  46.185  -1.786  0.33  18.167 ? 366 LYS D HD2  1 c 
ATOM   6729 H HD3  . LYS B 1 198 ? 31.557  47.602  -1.077  0.33  18.167 ? 366 LYS D HD3  1 c 
ATOM   6730 H HE2  . LYS B 1 198 ? 32.412  45.154  0.11    0.33  19.301 ? 366 LYS D HE2  1 c 
ATOM   6731 H HE3  . LYS B 1 198 ? 33.397  46.217  -0.523  0.33  19.301 ? 366 LYS D HE3  1 c 
ATOM   6732 H HZ1  . LYS B 1 198 ? 31.802  46.716  1.653   0.33  19.019 ? 366 LYS D HZ1  1 c 
ATOM   6733 H HZ2  . LYS B 1 198 ? 32.725  47.707  1.063   0.33  19.019 ? 366 LYS D HZ2  1 c 
ATOM   6734 H HZ3  . LYS B 1 198 ? 33.262  46.502  1.727   0.33  19.019 ? 366 LYS D HZ3  1 c 
ATOM   6735 N N    . VAL B 1 199 ? 28.096  48.378  -3.853  0.33  11.413 ? 367 VAL D N    1 ? 
ATOM   6736 C CA   . VAL B 1 199 ? 27.137  48.585  -4.918  0.33  11.919 ? 367 VAL D CA   1 ? 
ATOM   6737 C C    . VAL B 1 199 ? 27.023  47.279  -5.691  0.33  11.256 ? 367 VAL D C    1 ? 
ATOM   6738 O O    . VAL B 1 199 ? 27.998  46.789  -6.267  0.33  12.124 ? 367 VAL D O    1 ? 
ATOM   6739 C CB   . VAL B 1 199 ? 27.539  49.762  -5.819  0.33  12.884 ? 367 VAL D CB   1 ? 
ATOM   6740 C CG1  . VAL B 1 199 ? 26.675  49.837  -7.077  0.33  13.536 ? 367 VAL D CG1  1 ? 
ATOM   6741 C CG2  . VAL B 1 199 ? 27.473  51.073  -5.05   0.33  13.607 ? 367 VAL D CG2  1 ? 
ATOM   6742 H H    . VAL B 1 199 ? 28.939  48.103  -4.073  0.33  11.716 ? 367 VAL D H    1 c 
ATOM   6743 H HA   . VAL B 1 199 ? 26.27   48.785  -4.515  0.33  11.862 ? 367 VAL D HA   1 c 
ATOM   6744 H HB   . VAL B 1 199 ? 28.474  49.615  -6.096  0.33  12.946 ? 367 VAL D HB   1 c 
ATOM   6745 H HG11 . VAL B 1 199 ? 25.744  49.954  -6.824  0.33  13.341 ? 367 VAL D HG11 1 c 
ATOM   6746 H HG12 . VAL B 1 199 ? 26.771  49.014  -7.586  0.33  13.341 ? 367 VAL D HG12 1 c 
ATOM   6747 H HG13 . VAL B 1 199 ? 26.959  50.589  -7.622  0.33  13.341 ? 367 VAL D HG13 1 c 
ATOM   6748 H HG21 . VAL B 1 199 ? 27.723  51.807  -5.636  0.33  13.39  ? 367 VAL D HG21 1 c 
ATOM   6749 H HG22 . VAL B 1 199 ? 28.086  51.038  -4.296  0.33  13.39  ? 367 VAL D HG22 1 c 
ATOM   6750 H HG23 . VAL B 1 199 ? 26.568  51.213  -4.724  0.33  13.39  ? 367 VAL D HG23 1 c 
ATOM   6751 N N    . VAL B 1 200 ? 25.792  46.761  -5.701  0.33  11.369 ? 368 VAL D N    1 ? 
ATOM   6752 C CA   . VAL B 1 200 ? 25.459  45.489  -6.313  0.33  11.491 ? 368 VAL D CA   1 ? 
ATOM   6753 C C    . VAL B 1 200 ? 24.215  45.648  -7.178  0.33  11.613 ? 368 VAL D C    1 ? 
ATOM   6754 O O    . VAL B 1 200 ? 23.092  45.614  -6.688  0.33  11.975 ? 368 VAL D O    1 ? 
ATOM   6755 C CB   . VAL B 1 200 ? 25.243  44.422  -5.229  0.33  11.117 ? 368 VAL D CB   1 ? 
ATOM   6756 C CG1  . VAL B 1 200 ? 24.982  43.056  -5.845  0.33  11.211 ? 368 VAL D CG1  1 ? 
ATOM   6757 C CG2  . VAL B 1 200 ? 26.403  44.377  -4.248  0.33  11.588 ? 368 VAL D CG2  1 ? 
ATOM   6758 H H    . VAL B 1 200 ? 25.121  47.234  -5.299  0.33  11.37  ? 368 VAL D H    1 c 
ATOM   6759 H HA   . VAL B 1 200 ? 26.204  45.213  -6.881  0.33  11.421 ? 368 VAL D HA   1 c 
ATOM   6760 H HB   . VAL B 1 200 ? 24.436  44.681  -4.725  0.33  11.291 ? 368 VAL D HB   1 c 
ATOM   6761 H HG11 . VAL B 1 200 ? 25.741  42.796  -6.393  0.33  11.184 ? 368 VAL D HG11 1 c 
ATOM   6762 H HG12 . VAL B 1 200 ? 24.183  43.095  -6.396  0.33  11.184 ? 368 VAL D HG12 1 c 
ATOM   6763 H HG13 . VAL B 1 200 ? 24.854  42.4    -5.138  0.33  11.184 ? 368 VAL D HG13 1 c 
ATOM   6764 H HG21 . VAL B 1 200 ? 26.234  43.698  -3.574  0.33  11.447 ? 368 VAL D HG21 1 c 
ATOM   6765 H HG22 . VAL B 1 200 ? 26.498  45.243  -3.816  0.33  11.447 ? 368 VAL D HG22 1 c 
ATOM   6766 H HG23 . VAL B 1 200 ? 27.223  44.163  -4.724  0.33  11.447 ? 368 VAL D HG23 1 c 
ATOM   6767 N N    . PRO B 1 201 ? 24.384  45.808  -8.506  0.33  12.595 ? 369 PRO D N    1 ? 
ATOM   6768 C CA   . PRO B 1 201 ? 23.243  45.78   -9.42   0.33  12.343 ? 369 PRO D CA   1 ? 
ATOM   6769 C C    . PRO B 1 201 ? 22.689  44.366  -9.496  0.33  12.252 ? 369 PRO D C    1 ? 
ATOM   6770 O O    . PRO B 1 201 ? 23.438  43.426  -9.311  0.33  12.313 ? 369 PRO D O    1 ? 
ATOM   6771 C CB   . PRO B 1 201 ? 23.836  46.239  -10.762 0.33  12.885 ? 369 PRO D CB   1 ? 
ATOM   6772 C CG   . PRO B 1 201 ? 25.318  45.877  -10.672 0.33  13.002 ? 369 PRO D CG   1 ? 
ATOM   6773 C CD   . PRO B 1 201 ? 25.663  46.041  -9.191  0.33  12.593 ? 369 PRO D CD   1 ? 
ATOM   6774 H HA   . PRO B 1 201 ? 22.545  46.414  -9.117  0.33  12.471 ? 369 PRO D HA   1 c 
ATOM   6775 H HB2  . PRO B 1 201 ? 23.405  45.769  -11.515 0.33  12.788 ? 369 PRO D HB2  1 c 
ATOM   6776 H HB3  . PRO B 1 201 ? 23.718  47.21   -10.884 0.33  12.788 ? 369 PRO D HB3  1 c 
ATOM   6777 H HG2  . PRO B 1 201 ? 25.471  44.955  -10.965 0.33  12.883 ? 369 PRO D HG2  1 c 
ATOM   6778 H HG3  . PRO B 1 201 ? 25.859  46.479  -11.224 0.33  12.883 ? 369 PRO D HG3  1 c 
ATOM   6779 H HD2  . PRO B 1 201 ? 26.338  45.382  -8.913  0.33  12.683 ? 369 PRO D HD2  1 c 
ATOM   6780 H HD3  . PRO B 1 201 ? 26.003  46.945  -9.007  0.33  12.683 ? 369 PRO D HD3  1 c 
ATOM   6781 N N    . GLN B 1 202 ? 21.401  44.239  -9.827  0.33  12.99  ? 370 GLN D N    1 ? 
ATOM   6782 C CA   . GLN B 1 202 ? 20.81   42.937  -10.063 0.33  13.059 ? 370 GLN D CA   1 ? 
ATOM   6783 C C    . GLN B 1 202 ? 20.479  42.788  -11.545 0.33  13.071 ? 370 GLN D C    1 ? 
ATOM   6784 O O    . GLN B 1 202 ? 19.852  43.67   -12.12  0.33  13.163 ? 370 GLN D O    1 ? 
ATOM   6785 C CB   . GLN B 1 202 ? 19.542  42.737  -9.233  0.33  12.511 ? 370 GLN D CB   1 ? 
ATOM   6786 C CG   . GLN B 1 202 ? 18.926  41.353  -9.415  0.33  12.198 ? 370 GLN D CG   1 ? 
ATOM   6787 C CD   . GLN B 1 202 ? 17.709  41.118  -8.537  0.33  12.075 ? 370 GLN D CD   1 ? 
ATOM   6788 O OE1  . GLN B 1 202 ? 17.692  40.228  -7.685  0.33  11.723 ? 370 GLN D OE1  1 ? 
ATOM   6789 N NE2  . GLN B 1 202 ? 16.648  41.886  -8.755  0.33  12.559 ? 370 GLN D NE2  1 ? 
ATOM   6790 H H    . GLN B 1 202 ? 20.88   44.985  -9.908  0.33  12.826 ? 370 GLN D H    1 c 
ATOM   6791 H HA   . GLN B 1 202 ? 21.473  42.244  -9.814  0.33  12.946 ? 370 GLN D HA   1 c 
ATOM   6792 H HB2  . GLN B 1 202 ? 19.758  42.869  -8.286  0.33  12.561 ? 370 GLN D HB2  1 c 
ATOM   6793 H HB3  . GLN B 1 202 ? 18.884  43.416  -9.489  0.33  12.561 ? 370 GLN D HB3  1 c 
ATOM   6794 H HG2  . GLN B 1 202 ? 18.664  41.238  -10.353 0.33  12.24  ? 370 GLN D HG2  1 c 
ATOM   6795 H HG3  . GLN B 1 202 ? 19.599  40.671  -9.208  0.33  12.24  ? 370 GLN D HG3  1 c 
ATOM   6796 H HE21 . GLN B 1 202 ? 15.916  41.779  -8.264  0.33  12.408 ? 370 GLN D HE21 1 c 
ATOM   6797 H HE22 . GLN B 1 202 ? 16.672  42.505  -9.39   0.33  12.408 ? 370 GLN D HE22 1 c 
ATOM   6798 N N    . ASN B 1 203 ? 20.896  41.657  -12.116 0.33  13.594 ? 371 ASN D N    1 ? 
ATOM   6799 C CA   . ASN B 1 203 ? 20.652  41.275  -13.497 0.33  13.807 ? 371 ASN D CA   1 ? 
ATOM   6800 C C    . ASN B 1 203 ? 21.444  42.165  -14.468 0.33  14.639 ? 371 ASN D C    1 ? 
ATOM   6801 O O    . ASN B 1 203 ? 22.294  42.953  -14.063 0.33  13.798 ? 371 ASN D O    1 ? 
ATOM   6802 C CB   . ASN B 1 203 ? 19.154  41.177  -13.761 0.33  13.067 ? 371 ASN D CB   1 ? 
ATOM   6803 C CG   . ASN B 1 203 ? 18.525  40.13   -12.867 0.33  13.086 ? 371 ASN D CG   1 ? 
ATOM   6804 O OD1  . ASN B 1 203 ? 19.167  39.108  -12.605 0.33  12.507 ? 371 ASN D OD1  1 ? 
ATOM   6805 N ND2  . ASN B 1 203 ? 17.327  40.385  -12.361 0.33  13.115 ? 371 ASN D ND2  1 ? 
ATOM   6806 H H    . ASN B 1 203 ? 21.374  41.076  -11.596 0.33  13.515 ? 371 ASN D H    1 c 
ATOM   6807 H HA   . ASN B 1 203 ? 21.007  40.364  -13.604 0.33  13.772 ? 371 ASN D HA   1 c 
ATOM   6808 H HB2  . ASN B 1 203 ? 18.736  42.045  -13.591 0.33  13.235 ? 371 ASN D HB2  1 c 
ATOM   6809 H HB3  . ASN B 1 203 ? 19.002  40.94   -14.698 0.33  13.235 ? 371 ASN D HB3  1 c 
ATOM   6810 H HD21 . ASN B 1 203 ? 16.932  39.787  -11.838 0.33  13.106 ? 371 ASN D HD21 1 c 
ATOM   6811 H HD22 . ASN B 1 203 ? 16.923  41.152  -12.545 0.33  13.106 ? 371 ASN D HD22 1 c 
ATOM   6812 N N    . SER B 1 204 ? 21.177  41.985  -15.767 0.33  15.659 ? 372 SER D N    1 ? 
ATOM   6813 C CA   . SER B 1 204 ? 21.813  42.751  -16.838 0.33  17.444 ? 372 SER D CA   1 ? 
ATOM   6814 C C    . SER B 1 204 ? 23.336  42.622  -16.798 0.33  17.914 ? 372 SER D C    1 ? 
ATOM   6815 O O    . SER B 1 204 ? 24.057  43.6    -16.934 0.33  20.69  ? 372 SER D O    1 ? 
ATOM   6816 C CB   . SER B 1 204 ? 21.396  44.203  -16.804 0.33  18.098 ? 372 SER D CB   1 ? 
ATOM   6817 O OG   . SER B 1 204 ? 20      44.36   -16.999 0.33  18.7   ? 372 SER D OG   1 ? 
ATOM   6818 H H    . SER B 1 204 ? 20.563  41.349  -15.999 0.33  15.789 ? 372 SER D H    1 c 
ATOM   6819 H HA   . SER B 1 204 ? 21.504  42.369  -17.699 0.33  17.283 ? 372 SER D HA   1 c 
ATOM   6820 H HB2  . SER B 1 204 ? 21.646  44.587  -15.942 0.33  18.088 ? 372 SER D HB2  1 c 
ATOM   6821 H HB3  . SER B 1 204 ? 21.875  44.69   -17.501 0.33  18.088 ? 372 SER D HB3  1 c 
ATOM   6822 N N    . PRO B 1 205 ? 23.912  41.41   -16.67  0.33  18.212 ? 373 PRO D N    1 ? 
ATOM   6823 C CA   . PRO B 1 205 ? 25.368  41.263  -16.607 0.33  18.763 ? 373 PRO D CA   1 ? 
ATOM   6824 C C    . PRO B 1 205 ? 26.125  41.676  -17.871 0.33  18.604 ? 373 PRO D C    1 ? 
ATOM   6825 O O    . PRO B 1 205 ? 27.341  41.856  -17.843 0.33  17.865 ? 373 PRO D O    1 ? 
ATOM   6826 C CB   . PRO B 1 205 ? 25.509  39.77   -16.32  0.33  20.11  ? 373 PRO D CB   1 ? 
ATOM   6827 C CG   . PRO B 1 205 ? 24.296  39.181  -16.979 0.33  18.645 ? 373 PRO D CG   1 ? 
ATOM   6828 C CD   . PRO B 1 205 ? 23.196  40.129  -16.59  0.33  19.383 ? 373 PRO D CD   1 ? 
ATOM   6829 H HA   . PRO B 1 205 ? 25.707  41.779  -15.834 0.33  18.863 ? 373 PRO D HA   1 c 
ATOM   6830 H HB2  . PRO B 1 205 ? 26.337  39.409  -16.715 0.33  19.464 ? 373 PRO D HB2  1 c 
ATOM   6831 H HB3  . PRO B 1 205 ? 25.506  39.594  -15.35  0.33  19.464 ? 373 PRO D HB3  1 c 
ATOM   6832 H HG2  . PRO B 1 205 ? 24.403  39.149  -17.953 0.33  19.136 ? 373 PRO D HG2  1 c 
ATOM   6833 H HG3  . PRO B 1 205 ? 24.116  38.277  -16.646 0.33  19.136 ? 373 PRO D HG3  1 c 
ATOM   6834 H HD2  . PRO B 1 205 ? 22.447  40.092  -17.225 0.33  18.94  ? 373 PRO D HD2  1 c 
ATOM   6835 H HD3  . PRO B 1 205 ? 22.873  39.951  -15.678 0.33  18.94  ? 373 PRO D HD3  1 c 
ATOM   6836 N N    . GLU B 1 206 ? 25.4    41.785  -18.986 0.33  18.327 ? 374 GLU D N    1 ? 
ATOM   6837 C CA   . GLU B 1 206 ? 26.01   42.115  -20.268 0.33  17.864 ? 374 GLU D CA   1 ? 
ATOM   6838 C C    . GLU B 1 206 ? 26.532  43.551  -20.245 0.33  17.474 ? 374 GLU D C    1 ? 
ATOM   6839 O O    . GLU B 1 206 ? 27.328  43.938  -21.103 0.33  17.283 ? 374 GLU D O    1 ? 
ATOM   6840 C CB   . GLU B 1 206 ? 25.028  41.95   -21.43  0.33  17.503 ? 374 GLU D CB   1 ? 
ATOM   6841 C CG   . GLU B 1 206 ? 23.783  42.823  -21.338 0.33  17.864 ? 374 GLU D CG   1 ? 
ATOM   6842 C CD   . GLU B 1 206 ? 22.624  42.319  -20.484 0.33  18.194 ? 374 GLU D CD   1 ? 
ATOM   6843 O OE1  . GLU B 1 206 ? 22.733  41.273  -19.803 0.33  20.071 ? 374 GLU D OE1  1 ? 
ATOM   6844 O OE2  . GLU B 1 206 ? 21.58   42.989  -20.526 0.33  16.857 ? 374 GLU D OE2  1 ? 
ATOM   6845 H H    . GLU B 1 206 ? 24.496  41.649  -18.949 0.33  18.288 ? 374 GLU D H    1 c 
ATOM   6846 H HA   . GLU B 1 206 ? 26.776  41.504  -20.412 0.33  17.815 ? 374 GLU D HA   1 c 
ATOM   6847 H HB2  . GLU B 1 206 ? 25.495  42.159  -22.266 0.33  17.667 ? 374 GLU D HB2  1 c 
ATOM   6848 H HB3  . GLU B 1 206 ? 24.749  41.012  -21.473 0.33  17.667 ? 374 GLU D HB3  1 c 
ATOM   6849 H HG2  . GLU B 1 206 ? 24.049  43.702  -20.993 0.33  17.856 ? 374 GLU D HG2  1 c 
ATOM   6850 H HG3  . GLU B 1 206 ? 23.444  42.971  -22.246 0.33  17.856 ? 374 GLU D HG3  1 c 
ATOM   6851 N N    . LEU B 1 207 ? 26.133  44.318  -19.222 0.33  18.452 ? 375 LEU D N    1 ? 
ATOM   6852 C CA   . LEU B 1 207 ? 26.594  45.689  -19.063 0.33  18.113 ? 375 LEU D CA   1 ? 
ATOM   6853 C C    . LEU B 1 207 ? 28.083  45.704  -18.732 0.33  19.66  ? 375 LEU D C    1 ? 
ATOM   6854 O O    . LEU B 1 207 ? 28.72   46.739  -18.836 0.33  20.74  ? 375 LEU D O    1 ? 
ATOM   6855 C CB   . LEU B 1 207 ? 25.767  46.464  -18.038 0.33  17.564 ? 375 LEU D CB   1 ? 
ATOM   6856 C CG   . LEU B 1 207 ? 24.295  46.709  -18.395 0.33  17.083 ? 375 LEU D CG   1 ? 
ATOM   6857 C CD1  . LEU B 1 207 ? 23.572  47.475  -17.292 0.33  17.032 ? 375 LEU D CD1  1 ? 
ATOM   6858 C CD2  . LEU B 1 207 ? 24.142  47.427  -19.737 0.33  18.143 ? 375 LEU D CD2  1 ? 
ATOM   6859 H H    . LEU B 1 207 ? 25.555  43.973  -18.604 0.33  18.138 ? 375 LEU D H    1 c 
ATOM   6860 H HA   . LEU B 1 207 ? 26.487  46.135  -19.942 0.33  18.353 ? 375 LEU D HA   1 c 
ATOM   6861 H HB2  . LEU B 1 207 ? 25.801  45.973  -17.184 0.33  17.577 ? 375 LEU D HB2  1 c 
ATOM   6862 H HB3  . LEU B 1 207 ? 26.2    47.337  -17.892 0.33  17.577 ? 375 LEU D HB3  1 c 
ATOM   6863 H HG   . LEU B 1 207 ? 23.854  45.825  -18.48  0.33  17.354 ? 375 LEU D HG   1 c 
ATOM   6864 H HD11 . LEU B 1 207 ? 23.601  46.962  -16.467 0.33  17.047 ? 375 LEU D HD11 1 c 
ATOM   6865 H HD12 . LEU B 1 207 ? 22.646  47.621  -17.55  0.33  17.047 ? 375 LEU D HD12 1 c 
ATOM   6866 H HD13 . LEU B 1 207 ? 24.007  48.333  -17.153 0.33  17.047 ? 375 LEU D HD13 1 c 
ATOM   6867 H HD21 . LEU B 1 207 ? 24.538  46.888  -20.442 0.33  17.825 ? 375 LEU D HD21 1 c 
ATOM   6868 H HD22 . LEU B 1 207 ? 24.591  48.288  -19.698 0.33  17.825 ? 375 LEU D HD22 1 c 
ATOM   6869 H HD23 . LEU B 1 207 ? 23.198  47.564  -19.926 0.33  17.825 ? 375 LEU D HD23 1 c 
ATOM   6870 N N    . VAL B 1 208 ? 28.635  44.536  -18.401 0.33  20.116 ? 376 VAL D N    1 ? 
ATOM   6871 C CA   . VAL B 1 208 ? 30.048  44.361  -18.145 0.33  20.012 ? 376 VAL D CA   1 ? 
ATOM   6872 C C    . VAL B 1 208 ? 30.886  44.822  -19.343 0.33  21.859 ? 376 VAL D C    1 ? 
ATOM   6873 O O    . VAL B 1 208 ? 32.07   45.079  -19.173 0.33  22.429 ? 376 VAL D O    1 ? 
ATOM   6874 C CB   . VAL B 1 208 ? 30.379  42.894  -17.823 0.33  19.681 ? 376 VAL D CB   1 ? 
ATOM   6875 C CG1  . VAL B 1 208 ? 30.32   41.992  -19.067 0.33  20.088 ? 376 VAL D CG1  1 ? 
ATOM   6876 C CG2  . VAL B 1 208 ? 31.729  42.786  -17.117 0.33  18.912 ? 376 VAL D CG2  1 ? 
ATOM   6877 H H    . VAL B 1 208 ? 28.091  43.805  -18.331 0.33  19.983 ? 376 VAL D H    1 c 
ATOM   6878 H HA   . VAL B 1 208 ? 30.288  44.908  -17.372 0.33  20.297 ? 376 VAL D HA   1 c 
ATOM   6879 H HB   . VAL B 1 208 ? 29.69   42.575  -17.194 0.33  19.67  ? 376 VAL D HB   1 c 
ATOM   6880 H HG11 . VAL B 1 208 ? 30.96   42.307  -19.728 0.33  19.968 ? 376 VAL D HG11 1 c 
ATOM   6881 H HG12 . VAL B 1 208 ? 29.425  42.019  -19.446 0.33  19.968 ? 376 VAL D HG12 1 c 
ATOM   6882 H HG13 . VAL B 1 208 ? 30.538  41.078  -18.817 0.33  19.968 ? 376 VAL D HG13 1 c 
ATOM   6883 H HG21 . VAL B 1 208 ? 31.922  41.853  -16.925 0.33  19.135 ? 376 VAL D HG21 1 c 
ATOM   6884 H HG22 . VAL B 1 208 ? 31.701  43.287  -16.284 0.33  19.135 ? 376 VAL D HG22 1 c 
ATOM   6885 H HG23 . VAL B 1 208 ? 32.425  43.149  -17.689 0.33  19.135 ? 376 VAL D HG23 1 c 
ATOM   6886 N N    . ASP B 1 209 ? 30.298  44.88   -20.542 0.33  23.523 ? 377 ASP D N    1 ? 
ATOM   6887 C CA   . ASP B 1 209 ? 31.043  45.272  -21.73  0.33  24.705 ? 377 ASP D CA   1 ? 
ATOM   6888 C C    . ASP B 1 209 ? 31.426  46.746  -21.636 0.33  24.412 ? 377 ASP D C    1 ? 
ATOM   6889 O O    . ASP B 1 209 ? 32.397  47.167  -22.257 0.33  22.16  ? 377 ASP D O    1 ? 
ATOM   6890 C CB   . ASP B 1 209 ? 30.254  45.06   -23.013 0.33  26.2   ? 377 ASP D CB   1 ? 
ATOM   6891 C CG   . ASP B 1 209 ? 30.039  43.616  -23.46  0.33  27.49  ? 377 ASP D CG   1 ? 
ATOM   6892 O OD1  . ASP B 1 209 ? 30.986  42.808  -23.355 0.33  26.358 ? 377 ASP D OD1  1 ? 
ATOM   6893 O OD2  . ASP B 1 209 ? 28.934  43.327  -23.975 0.33  31.26  ? 377 ASP D OD2  1 ? 
ATOM   6894 H H    . ASP B 1 209 ? 29.412  44.671  -20.622 0.33  23.37  ? 377 ASP D H    1 c 
ATOM   6895 H HA   . ASP B 1 209 ? 31.864  44.733  -21.774 0.33  24.682 ? 377 ASP D HA   1 c 
ATOM   6896 H HB2  . ASP B 1 209 ? 29.372  45.473  -22.904 0.33  26.136 ? 377 ASP D HB2  1 c 
ATOM   6897 H HB3  . ASP B 1 209 ? 30.715  45.531  -23.738 0.33  26.136 ? 377 ASP D HB3  1 c 
ATOM   6898 N N    . ASP B 1 210 ? 30.63   47.53   -20.892 0.33  23.014 ? 378 ASP D N    1 ? 
ATOM   6899 C CA   . ASP B 1 210 ? 30.871  48.957  -20.742 0.33  21.628 ? 378 ASP D CA   1 ? 
ATOM   6900 C C    . ASP B 1 210 ? 32.03   49.17   -19.774 0.33  20.94  ? 378 ASP D C    1 ? 
ATOM   6901 O O    . ASP B 1 210 ? 31.954  48.747  -18.626 0.33  19.662 ? 378 ASP D O    1 ? 
ATOM   6902 C CB   . ASP B 1 210 ? 29.626  49.666  -20.232 0.33  21.487 ? 378 ASP D CB   1 ? 
ATOM   6903 C CG   . ASP B 1 210 ? 29.663  51.186  -20.287 0.33  20.392 ? 378 ASP D CG   1 ? 
ATOM   6904 O OD1  . ASP B 1 210 ? 30.725  51.756  -19.981 0.33  21.637 ? 378 ASP D OD1  1 ? 
ATOM   6905 O OD2  . ASP B 1 210 ? 28.63   51.779  -20.638 0.33  20.772 ? 378 ASP D OD2  1 ? 
ATOM   6906 H H    . ASP B 1 210 ? 29.913  47.159  -20.465 0.33  23.015 ? 378 ASP D H    1 c 
ATOM   6907 H HA   . ASP B 1 210 ? 31.114  49.328  -21.62  0.33  21.737 ? 378 ASP D HA   1 c 
ATOM   6908 H HB2  . ASP B 1 210 ? 28.857  49.362  -20.757 0.33  21.262 ? 378 ASP D HB2  1 c 
ATOM   6909 H HB3  . ASP B 1 210 ? 29.476  49.4    -19.3   0.33  21.262 ? 378 ASP D HB3  1 c 
ATOM   6910 N N    . PRO B 1 211 ? 33.129  49.857  -20.17  0.33  20.217 ? 379 PRO D N    1 ? 
ATOM   6911 C CA   . PRO B 1 211 ? 34.263  50.045  -19.263 0.33  20.309 ? 379 PRO D CA   1 ? 
ATOM   6912 C C    . PRO B 1 211 ? 33.91   50.749  -17.952 0.33  18.327 ? 379 PRO D C    1 ? 
ATOM   6913 O O    . PRO B 1 211 ? 34.645  50.616  -16.98  0.33  22.128 ? 379 PRO D O    1 ? 
ATOM   6914 C CB   . PRO B 1 211 ? 35.341  50.833  -20.067 0.33  20.666 ? 379 PRO D CB   1 ? 
ATOM   6915 C CG   . PRO B 1 211 ? 34.701  51.146  -21.411 0.33  21.002 ? 379 PRO D CG   1 ? 
ATOM   6916 C CD   . PRO B 1 211 ? 33.336  50.475  -21.49  0.33  21.111 ? 379 PRO D CD   1 ? 
ATOM   6917 H HA   . PRO B 1 211 ? 34.623  49.147  -19.052 0.33  19.974 ? 379 PRO D HA   1 c 
ATOM   6918 H HB2  . PRO B 1 211 ? 35.589  51.663  -19.597 0.33  20.662 ? 379 PRO D HB2  1 c 
ATOM   6919 H HB3  . PRO B 1 211 ? 36.154  50.287  -20.187 0.33  20.662 ? 379 PRO D HB3  1 c 
ATOM   6920 H HG2  . PRO B 1 211 ? 34.602  52.115  -21.515 0.33  20.95  ? 379 PRO D HG2  1 c 
ATOM   6921 H HG3  . PRO B 1 211 ? 35.274  50.821  -22.137 0.33  20.95  ? 379 PRO D HG3  1 c 
ATOM   6922 H HD2  . PRO B 1 211 ? 32.634  51.137  -21.679 0.33  20.875 ? 379 PRO D HD2  1 c 
ATOM   6923 H HD3  . PRO B 1 211 ? 33.324  49.794  -22.199 0.33  20.875 ? 379 PRO D HD3  1 c 
ATOM   6924 N N    . ALA B 1 212 ? 32.795  51.487  -17.902 0.33  16.948 ? 380 ALA D N    1 ? 
ATOM   6925 C CA   . ALA B 1 212 ? 32.447  52.223  -16.693 0.33  15.351 ? 380 ALA D CA   1 ? 
ATOM   6926 C C    . ALA B 1 212 ? 31.786  51.296  -15.667 0.33  15.557 ? 380 ALA D C    1 ? 
ATOM   6927 O O    . ALA B 1 212 ? 31.628  51.687  -14.509 0.33  15.413 ? 380 ALA D O    1 ? 
ATOM   6928 C CB   . ALA B 1 212 ? 31.557  53.404  -17.01  0.33  14.982 ? 380 ALA D CB   1 ? 
ATOM   6929 H H    . ALA B 1 212 ? 32.243  51.534  -18.629 0.33  16.889 ? 380 ALA D H    1 c 
ATOM   6930 H HA   . ALA B 1 212 ? 33.294  52.563  -16.292 0.33  15.619 ? 380 ALA D HA   1 c 
ATOM   6931 H HB1  . ALA B 1 212 ? 32.017  54.006  -17.619 0.33  15.09  ? 380 ALA D HB1  1 c 
ATOM   6932 H HB2  . ALA B 1 212 ? 30.736  53.092  -17.426 0.33  15.09  ? 380 ALA D HB2  1 c 
ATOM   6933 H HB3  . ALA B 1 212 ? 31.341  53.88   -16.19  0.33  15.09  ? 380 ALA D HB3  1 c 
ATOM   6934 N N    . TYR B 1 213 ? 31.45   50.069  -16.082 0.33  14.848 ? 381 TYR D N    1 ? 
ATOM   6935 C CA   . TYR B 1 213 ? 30.646  49.181  -15.249 0.33  15.226 ? 381 TYR D CA   1 ? 
ATOM   6936 C C    . TYR B 1 213 ? 31.46   48.602  -14.096 0.33  16.115 ? 381 TYR D C    1 ? 
ATOM   6937 O O    . TYR B 1 213 ? 31.125  48.793  -12.92  0.33  16.604 ? 381 TYR D O    1 ? 
ATOM   6938 C CB   . TYR B 1 213 ? 30.052  48.065  -16.119 0.33  14.838 ? 381 TYR D CB   1 ? 
ATOM   6939 C CG   . TYR B 1 213 ? 29.174  47.065  -15.377 0.33  14.596 ? 381 TYR D CG   1 ? 
ATOM   6940 C CD1  . TYR B 1 213 ? 27.86   47.376  -15.052 0.33  15.608 ? 381 TYR D CD1  1 ? 
ATOM   6941 C CD2  . TYR B 1 213 ? 29.651  45.812  -15.042 0.33  14.681 ? 381 TYR D CD2  1 ? 
ATOM   6942 C CE1  . TYR B 1 213 ? 27.052  46.476  -14.38  0.33  14.515 ? 381 TYR D CE1  1 ? 
ATOM   6943 C CE2  . TYR B 1 213 ? 28.85   44.894  -14.393 0.33  14.933 ? 381 TYR D CE2  1 ? 
ATOM   6944 C CZ   . TYR B 1 213 ? 27.548  45.225  -14.067 0.33  14.81  ? 381 TYR D CZ   1 ? 
ATOM   6945 O OH   . TYR B 1 213 ? 26.764  44.326  -13.408 0.33  14.543 ? 381 TYR D OH   1 ? 
ATOM   6946 H H    . TYR B 1 213 ? 31.727  49.777  -16.902 0.33  15.099 ? 381 TYR D H    1 c 
ATOM   6947 H HA   . TYR B 1 213 ? 29.897  49.71   -14.866 0.33  15.239 ? 381 TYR D HA   1 c 
ATOM   6948 H HB2  . TYR B 1 213 ? 29.521  48.48   -16.834 0.33  14.869 ? 381 TYR D HB2  1 c 
ATOM   6949 H HB3  . TYR B 1 213 ? 30.792  47.578  -16.545 0.33  14.869 ? 381 TYR D HB3  1 c 
ATOM   6950 H HD1  . TYR B 1 213 ? 27.518  48.228  -15.27  0.33  15.099 ? 381 TYR D HD1  1 c 
ATOM   6951 H HD2  . TYR B 1 213 ? 30.536  45.575  -15.269 0.33  14.725 ? 381 TYR D HD2  1 c 
ATOM   6952 H HE1  . TYR B 1 213 ? 26.164  46.702  -14.164 0.33  14.829 ? 381 TYR D HE1  1 c 
ATOM   6953 H HE2  . TYR B 1 213 ? 29.192  44.046  -14.165 0.33  14.843 ? 381 TYR D HE2  1 c 
ATOM   6954 N N    . LEU B 1 214 ? 32.518  47.851  -14.425 0.33  16.154 ? 382 LEU D N    1 ? 
ATOM   6955 C CA   . LEU B 1 214 ? 33.219  47.092  -13.401 0.33  16.903 ? 382 LEU D CA   1 ? 
ATOM   6956 C C    . LEU B 1 214 ? 33.783  48.014  -12.324 0.33  16.265 ? 382 LEU D C    1 ? 
ATOM   6957 O O    . LEU B 1 214 ? 33.693  47.68   -11.145 0.33  16.263 ? 382 LEU D O    1 ? 
ATOM   6958 C CB   . LEU B 1 214 ? 34.273  46.169  -14.002 0.33  16.972 ? 382 LEU D CB   1 ? 
ATOM   6959 C CG   . LEU B 1 214 ? 33.713  44.877  -14.604 0.33  18.173 ? 382 LEU D CG   1 ? 
ATOM   6960 C CD1  . LEU B 1 214 ? 34.819  44.131  -15.264 0.33  17.986 ? 382 LEU D CD1  1 ? 
ATOM   6961 C CD2  . LEU B 1 214 ? 33.039  43.982  -13.572 0.33  18.503 ? 382 LEU D CD2  1 ? 
ATOM   6962 H H    . LEU B 1 214 ? 32.805  47.811  -15.292 0.33  16.31  ? 382 LEU D H    1 c 
ATOM   6963 H HA   . LEU B 1 214 ? 32.541  46.523  -12.957 0.33  16.648 ? 382 LEU D HA   1 c 
ATOM   6964 H HB2  . LEU B 1 214 ? 34.752  46.662  -14.708 0.33  17.221 ? 382 LEU D HB2  1 c 
ATOM   6965 H HB3  . LEU B 1 214 ? 34.918  45.933  -13.296 0.33  17.221 ? 382 LEU D HB3  1 c 
ATOM   6966 H HG   . LEU B 1 214 ? 33.043  45.118  -15.294 0.33  17.971 ? 382 LEU D HG   1 c 
ATOM   6967 H HD11 . LEU B 1 214 ? 35.205  44.678  -15.969 0.33  18.042 ? 382 LEU D HD11 1 c 
ATOM   6968 H HD12 . LEU B 1 214 ? 34.473  43.308  -15.648 0.33  18.042 ? 382 LEU D HD12 1 c 
ATOM   6969 H HD13 . LEU B 1 214 ? 35.505  43.918  -14.609 0.33  18.042 ? 382 LEU D HD13 1 c 
ATOM   6970 H HD21 . LEU B 1 214 ? 32.303  44.462  -13.156 0.33  18.406 ? 382 LEU D HD21 1 c 
ATOM   6971 H HD22 . LEU B 1 214 ? 33.685  43.727  -12.891 0.33  18.406 ? 382 LEU D HD22 1 c 
ATOM   6972 H HD23 . LEU B 1 214 ? 32.698  43.183  -14.007 0.33  18.406 ? 382 LEU D HD23 1 c 
ATOM   6973 N N    . PRO B 1 215 ? 34.358  49.199  -12.64  0.33  16.234 ? 383 PRO D N    1 ? 
ATOM   6974 C CA   . PRO B 1 215 ? 34.842  50.089  -11.58  0.33  16.08  ? 383 PRO D CA   1 ? 
ATOM   6975 C C    . PRO B 1 215 ? 33.768  50.65   -10.657 0.33  16.331 ? 383 PRO D C    1 ? 
ATOM   6976 O O    . PRO B 1 215 ? 34.088  51.163  -9.586  0.33  16.78  ? 383 PRO D O    1 ? 
ATOM   6977 C CB   . PRO B 1 215 ? 35.572  51.22   -12.332 0.33  15.893 ? 383 PRO D CB   1 ? 
ATOM   6978 C CG   . PRO B 1 215 ? 35.817  50.672  -13.724 0.33  16.113 ? 383 PRO D CG   1 ? 
ATOM   6979 C CD   . PRO B 1 215 ? 34.714  49.675  -13.995 0.33  16.167 ? 383 PRO D CD   1 ? 
ATOM   6980 H HA   . PRO B 1 215 ? 35.502  49.587  -11.04  0.33  16.122 ? 383 PRO D HA   1 c 
ATOM   6981 H HB2  . PRO B 1 215 ? 35.014  52.032  -12.369 0.33  15.984 ? 383 PRO D HB2  1 c 
ATOM   6982 H HB3  . PRO B 1 215 ? 36.424  51.442  -11.889 0.33  15.984 ? 383 PRO D HB3  1 c 
ATOM   6983 H HG2  . PRO B 1 215 ? 35.796  51.394  -14.386 0.33  16.076 ? 383 PRO D HG2  1 c 
ATOM   6984 H HG3  . PRO B 1 215 ? 36.692  50.234  -13.771 0.33  16.076 ? 383 PRO D HG3  1 c 
ATOM   6985 H HD2  . PRO B 1 215 ? 33.947  50.107  -14.433 0.33  16.17  ? 383 PRO D HD2  1 c 
ATOM   6986 H HD3  . PRO B 1 215 ? 35.035  48.937  -14.559 0.33  16.17  ? 383 PRO D HD3  1 c 
ATOM   6987 N N    . ALA B 1 216 ? 32.496  50.512  -11.046 0.33  15.687 ? 384 ALA D N    1 ? 
ATOM   6988 C CA   . ALA B 1 216 ? 31.42   51.116  -10.285 0.33  15.066 ? 384 ALA D CA   1 ? 
ATOM   6989 C C    . ALA B 1 216 ? 30.747  50.12   -9.339  0.33  14.516 ? 384 ALA D C    1 ? 
ATOM   6990 O O    . ALA B 1 216 ? 29.872  50.518  -8.586  0.33  16.38  ? 384 ALA D O    1 ? 
ATOM   6991 C CB   . ALA B 1 216 ? 30.403  51.717  -11.217 0.33  14.544 ? 384 ALA D CB   1 ? 
ATOM   6992 H H    . ALA B 1 216 ? 32.297  50.033  -11.798 0.33  15.695 ? 384 ALA D H    1 c 
ATOM   6993 H HA   . ALA B 1 216 ? 31.813  51.845  -9.729  0.33  14.984 ? 384 ALA D HA   1 c 
ATOM   6994 H HB1  . ALA B 1 216 ? 30.825  52.399  -11.766 0.33  14.697 ? 384 ALA D HB1  1 c 
ATOM   6995 H HB2  . ALA B 1 216 ? 30.036  51.024  -11.792 0.33  14.697 ? 384 ALA D HB2  1 c 
ATOM   6996 H HB3  . ALA B 1 216 ? 29.684  52.119  -10.702 0.33  14.697 ? 384 ALA D HB3  1 c 
ATOM   6997 N N    . ILE B 1 217 ? 31.082  48.83   -9.445  0.33  14.79  ? 385 ILE D N    1 ? 
ATOM   6998 C CA   . ILE B 1 217 ? 30.364  47.807  -8.697  0.33  14.409 ? 385 ILE D CA   1 ? 
ATOM   6999 C C    . ILE B 1 217 ? 31.306  46.989  -7.828  0.33  14.456 ? 385 ILE D C    1 ? 
ATOM   7000 O O    . ILE B 1 217 ? 32.498  46.848  -8.108  0.33  15.45  ? 385 ILE D O    1 ? 
ATOM   7001 C CB   . ILE B 1 217 ? 29.513  46.901  -9.616  0.33  14.582 ? 385 ILE D CB   1 ? 
ATOM   7002 C CG1  . ILE B 1 217 ? 30.361  45.906  -10.41  0.33  14.916 ? 385 ILE D CG1  1 ? 
ATOM   7003 C CG2  . ILE B 1 217 ? 28.605  47.75   -10.501 0.33  15.12  ? 385 ILE D CG2  1 ? 
ATOM   7004 C CD1  . ILE B 1 217 ? 29.576  44.759  -11.026 0.33  14.669 ? 385 ILE D CD1  1 ? 
ATOM   7005 H H    . ILE B 1 217 ? 31.771  48.581  -9.992  0.33  14.638 ? 385 ILE D H    1 c 
ATOM   7006 H HA   . ILE B 1 217 ? 29.746  48.271  -8.099  0.33  14.523 ? 385 ILE D HA   1 c 
ATOM   7007 H HB   . ILE B 1 217 ? 28.931  46.373  -9.033  0.33  14.711 ? 385 ILE D HB   1 c 
ATOM   7008 H HG12 . ILE B 1 217 ? 30.821  46.39   -11.126 0.33  14.783 ? 385 ILE D HG12 1 c 
ATOM   7009 H HG13 . ILE B 1 217 ? 31.044  45.534  -9.816  0.33  14.783 ? 385 ILE D HG13 1 c 
ATOM   7010 H HG21 . ILE B 1 217 ? 28.076  47.172  -11.076 0.33  14.959 ? 385 ILE D HG21 1 c 
ATOM   7011 H HG22 . ILE B 1 217 ? 29.146  48.343  -11.049 0.33  14.959 ? 385 ILE D HG22 1 c 
ATOM   7012 H HG23 . ILE B 1 217 ? 28.01   48.281  -9.944  0.33  14.959 ? 385 ILE D HG23 1 c 
ATOM   7013 H HD11 . ILE B 1 217 ? 29.142  44.243  -10.32  0.33  14.742 ? 385 ILE D HD11 1 c 
ATOM   7014 H HD12 . ILE B 1 217 ? 30.182  44.178  -11.524 0.33  14.742 ? 385 ILE D HD12 1 c 
ATOM   7015 H HD13 . ILE B 1 217 ? 28.898  45.114  -11.631 0.33  14.742 ? 385 ILE D HD13 1 c 
ATOM   7016 N N    . ASP B 1 218 ? 30.708  46.381  -6.797  0.33  14.988 ? 386 ASP D N    1 ? 
ATOM   7017 C CA   . ASP B 1 218 ? 31.425  45.496  -5.901  0.33  15.8   ? 386 ASP D CA   1 ? 
ATOM   7018 C C    . ASP B 1 218 ? 30.891  44.071  -5.998  0.33  14.96  ? 386 ASP D C    1 ? 
ATOM   7019 O O    . ASP B 1 218 ? 31.519  43.146  -5.513  0.33  13.958 ? 386 ASP D O    1 ? 
ATOM   7020 C CB   . ASP B 1 218 ? 31.32   45.982  -4.471  0.33  16.589 ? 386 ASP D CB   1 ? 
ATOM   7021 C CG   . ASP B 1 218 ? 31.797  47.411  -4.292  0.33  16.705 ? 386 ASP D CG   1 ? 
ATOM   7022 O OD1  . ASP B 1 218 ? 33.024  47.584  -4.275  0.33  17.331 ? 386 ASP D OD1  1 ? 
ATOM   7023 O OD2  . ASP B 1 218 ? 30.94   48.33   -4.18   0.33  15.79  ? 386 ASP D OD2  1 ? 
ATOM   7024 H H    . ASP B 1 218 ? 29.818  46.526  -6.651  0.33  15.038 ? 386 ASP D H    1 c 
ATOM   7025 H HA   . ASP B 1 218 ? 32.374  45.496  -6.16   0.33  15.624 ? 386 ASP D HA   1 c 
ATOM   7026 H HB2  . ASP B 1 218 ? 30.386  45.926  -4.18   0.33  16.431 ? 386 ASP D HB2  1 c 
ATOM   7027 H HB3  . ASP B 1 218 ? 31.856  45.399  -3.894  0.33  16.431 ? 386 ASP D HB3  1 c 
ATOM   7028 N N    . GLY B 1 219 ? 29.723  43.897  -6.606  0.33  15.283 ? 387 GLY D N    1 ? 
ATOM   7029 C CA   . GLY B 1 219 ? 29.071  42.606  -6.658  0.33  14.726 ? 387 GLY D CA   1 ? 
ATOM   7030 C C    . GLY B 1 219 ? 27.977  42.667  -7.716  0.33  14.354 ? 387 GLY D C    1 ? 
ATOM   7031 O O    . GLY B 1 219 ? 27.694  43.735  -8.252  0.33  14.412 ? 387 GLY D O    1 ? 
ATOM   7032 H H    . GLY B 1 219 ? 29.316  44.612  -7.005  0.33  15.078 ? 387 GLY D H    1 c 
ATOM   7033 H HA2  . GLY B 1 219 ? 29.73   41.909  -6.889  0.33  14.773 ? 387 GLY D HA2  1 c 
ATOM   7034 H HA3  . GLY B 1 219 ? 28.682  42.393  -5.778  0.33  14.773 ? 387 GLY D HA3  1 c 
ATOM   7035 N N    . LEU B 1 220 ? 27.385  41.522  -8.028  0.33  13.493 ? 388 LEU D N    1 ? 
ATOM   7036 C CA   . LEU B 1 220 ? 26.308  41.458  -9.005  0.33  12.963 ? 388 LEU D CA   1 ? 
ATOM   7037 C C    . LEU B 1 220 ? 25.329  40.423  -8.476  0.33  12.831 ? 388 LEU D C    1 ? 
ATOM   7038 O O    . LEU B 1 220 ? 25.771  39.35   -8.054  0.33  13.554 ? 388 LEU D O    1 ? 
ATOM   7039 C CB   . LEU B 1 220 ? 26.88   41.056  -10.365 0.33  13.231 ? 388 LEU D CB   1 ? 
ATOM   7040 C CG   . LEU B 1 220 ? 25.891  40.468  -11.381 0.33  13.443 ? 388 LEU D CG   1 ? 
ATOM   7041 C CD1  . LEU B 1 220 ? 25.022  41.564  -11.953 0.33  13.35  ? 388 LEU D CD1  1 ? 
ATOM   7042 C CD2  . LEU B 1 220 ? 26.597  39.678  -12.489 0.33  14.176 ? 388 LEU D CD2  1 ? 
ATOM   7043 H H    . LEU B 1 220 ? 27.657  40.751  -7.62   0.33  13.57  ? 388 LEU D H    1 c 
ATOM   7044 H HA   . LEU B 1 220 ? 25.867  42.343  -9.067  0.33  13.088 ? 388 LEU D HA   1 c 
ATOM   7045 H HB2  . LEU B 1 220 ? 27.299  41.852  -10.767 0.33  13.217 ? 388 LEU D HB2  1 c 
ATOM   7046 H HB3  . LEU B 1 220 ? 27.595  40.396  -10.213 0.33  13.217 ? 388 LEU D HB3  1 c 
ATOM   7047 H HG   . LEU B 1 220 ? 25.298  39.838  -10.896 0.33  13.518 ? 388 LEU D HG   1 c 
ATOM   7048 H HD11 . LEU B 1 220 ? 24.528  41.994  -11.236 0.33  13.378 ? 388 LEU D HD11 1 c 
ATOM   7049 H HD12 . LEU B 1 220 ? 24.398  41.183  -12.593 0.33  13.378 ? 388 LEU D HD12 1 c 
ATOM   7050 H HD13 . LEU B 1 220 ? 25.581  42.221  -12.4   0.33  13.378 ? 388 LEU D HD13 1 c 
ATOM   7051 H HD21 . LEU B 1 220 ? 27.092  38.939  -12.097 0.33  13.958 ? 388 LEU D HD21 1 c 
ATOM   7052 H HD22 . LEU B 1 220 ? 27.211  40.263  -12.964 0.33  13.958 ? 388 LEU D HD22 1 c 
ATOM   7053 H HD23 . LEU B 1 220 ? 25.936  39.33   -13.111 0.33  13.958 ? 388 LEU D HD23 1 c 
ATOM   7054 N N    . GLY B 1 221 ? 24.039  40.772  -8.465  0.33  13.024 ? 389 GLY D N    1 ? 
ATOM   7055 C CA   . GLY B 1 221 ? 22.986  39.812  -8.173  0.33  13.676 ? 389 GLY D CA   1 ? 
ATOM   7056 C C    . GLY B 1 221 ? 22.424  39.269  -9.479  0.33  13.579 ? 389 GLY D C    1 ? 
ATOM   7057 O O    . GLY B 1 221 ? 22.281  40.017  -10.44  0.33  13.594 ? 389 GLY D O    1 ? 
ATOM   7058 H H    . GLY B 1 221 ? 23.808  41.638  -8.645  0.33  13.122 ? 389 GLY D H    1 c 
ATOM   7059 H HA2  . GLY B 1 221 ? 23.353  39.075  -7.631  0.33  13.497 ? 389 GLY D HA2  1 c 
ATOM   7060 H HA3  . GLY B 1 221 ? 22.272  40.254  -7.656  0.33  13.497 ? 389 GLY D HA3  1 c 
ATOM   7061 N N    . MET B 1 222 ? 22.231  37.956  -9.562  0.33  12.888 ? 390 MET D N    1 ? 
ATOM   7062 C CA   . MET B 1 222 ? 21.683  37.361  -10.769 0.33  13.046 ? 390 MET D CA   1 ? 
ATOM   7063 C C    . MET B 1 222 ? 20.52   36.472  -10.368 0.33  13.465 ? 390 MET D C    1 ? 
ATOM   7064 O O    . MET B 1 222 ? 20.712  35.542  -9.605  0.33  12.995 ? 390 MET D O    1 ? 
ATOM   7065 C CB   . MET B 1 222 ? 22.718  36.511  -11.504 0.33  13.562 ? 390 MET D CB   1 ? 
ATOM   7066 C CG   . MET B 1 222 ? 23.775  37.31   -12.228 0.33  14.237 ? 390 MET D CG   1 ? 
ATOM   7067 S SD   . MET B 1 222 ? 23.134  38.327  -13.567 0.33  14.83  ? 390 MET D SD   1 ? 
ATOM   7068 C CE   . MET B 1 222 ? 22.399  37.077  -14.629 0.33  15.303 ? 390 MET D CE   1 ? 
ATOM   7069 H H    . MET B 1 222 ? 22.442  37.418  -8.854  0.33  13.086 ? 390 MET D H    1 c 
ATOM   7070 H HA   . MET B 1 222 ? 21.355  38.084  -11.362 0.33  13.183 ? 390 MET D HA   1 c 
ATOM   7071 H HB2  . MET B 1 222 ? 23.156  35.922  -10.853 0.33  13.594 ? 390 MET D HB2  1 c 
ATOM   7072 H HB3  . MET B 1 222 ? 22.25   35.942  -12.152 0.33  13.594 ? 390 MET D HB3  1 c 
ATOM   7073 H HG2  . MET B 1 222 ? 24.23   37.892  -11.587 0.33  14.181 ? 390 MET D HG2  1 c 
ATOM   7074 H HG3  . MET B 1 222 ? 24.441  36.696  -12.597 0.33  14.181 ? 390 MET D HG3  1 c 
ATOM   7075 H HE1  . MET B 1 222 ? 22.024  37.504  -15.421 0.33  15.184 ? 390 MET D HE1  1 c 
ATOM   7076 H HE2  . MET B 1 222 ? 23.083  36.437  -14.897 0.33  15.184 ? 390 MET D HE2  1 c 
ATOM   7077 H HE3  . MET B 1 222 ? 21.692  36.614  -14.144 0.33  15.184 ? 390 MET D HE3  1 c 
ATOM   7078 N N    . GLU B 1 223 ? 19.344  36.76   -10.919 0.33  13.973 ? 391 GLU D N    1 ? 
ATOM   7079 C CA   . GLU B 1 223 ? 18.196  35.896  -10.754 0.33  13.651 ? 391 GLU D CA   1 ? 
ATOM   7080 C C    . GLU B 1 223 ? 18.085  34.973  -11.966 0.33  13.496 ? 391 GLU D C    1 ? 
ATOM   7081 O O    . GLU B 1 223 ? 18.462  35.328  -13.08  0.33  14.356 ? 391 GLU D O    1 ? 
ATOM   7082 C CB   . GLU B 1 223 ? 16.908  36.706  -10.678 0.33  13.115 ? 391 GLU D CB   1 ? 
ATOM   7083 C CG   . GLU B 1 223 ? 16.775  37.599  -9.455  0.33  13.263 ? 391 GLU D CG   1 ? 
ATOM   7084 C CD   . GLU B 1 223 ? 15.496  38.398  -9.553  0.33  13.355 ? 391 GLU D CD   1 ? 
ATOM   7085 O OE1  . GLU B 1 223 ? 14.615  38.244  -8.689  0.33  15.125 ? 391 GLU D OE1  1 ? 
ATOM   7086 O OE2  . GLU B 1 223 ? 15.4    39.176  -10.521 0.33  14.563 ? 391 GLU D OE2  1 ? 
ATOM   7087 H H    . GLU B 1 223 ? 19.255  37.523  -11.415 0.33  13.778 ? 391 GLU D H    1 c 
ATOM   7088 H HA   . GLU B 1 223 ? 18.314  35.354  -9.933  0.33  13.587 ? 391 GLU D HA   1 c 
ATOM   7089 H HB2  . GLU B 1 223 ? 16.845  37.267  -11.479 0.33  13.269 ? 391 GLU D HB2  1 c 
ATOM   7090 H HB3  . GLU B 1 223 ? 16.149  36.086  -10.692 0.33  13.269 ? 391 GLU D HB3  1 c 
ATOM   7091 H HG2  . GLU B 1 223 ? 16.755  37.051  -8.642  0.33  13.25  ? 391 GLU D HG2  1 c 
ATOM   7092 H HG3  . GLU B 1 223 ? 17.539  38.214  -9.407  0.33  13.25  ? 391 GLU D HG3  1 c 
ATOM   7093 N N    . ASP B 1 224 ? 17.574  33.772  -11.72  0.33  13.906 ? 392 ASP D N    1 ? 
ATOM   7094 C CA   . ASP B 1 224 ? 16.991  32.927  -12.753 0.33  14.366 ? 392 ASP D CA   1 ? 
ATOM   7095 C C    . ASP B 1 224 ? 18.015  32.433  -13.774 0.33  14.177 ? 392 ASP D C    1 ? 
ATOM   7096 O O    . ASP B 1 224 ? 17.667  32.177  -14.924 0.33  14.902 ? 392 ASP D O    1 ? 
ATOM   7097 C CB   . ASP B 1 224 ? 15.86   33.642  -13.471 0.33  15.103 ? 392 ASP D CB   1 ? 
ATOM   7098 C CG   . ASP B 1 224 ? 14.613  33.876  -12.638 0.33  16.012 ? 392 ASP D CG   1 ? 
ATOM   7099 O OD1  . ASP B 1 224 ? 14.027  32.88   -12.156 0.33  15.874 ? 392 ASP D OD1  1 ? 
ATOM   7100 O OD2  . ASP B 1 224 ? 14.265  35.054  -12.449 0.33  19.531 ? 392 ASP D OD2  1 ? 
ATOM   7101 H H    . ASP B 1 224 ? 17.587  33.46   -10.861 0.33  13.909 ? 392 ASP D H    1 c 
ATOM   7102 H HA   . ASP B 1 224 ? 16.597  32.141  -12.312 0.33  14.375 ? 392 ASP D HA   1 c 
ATOM   7103 H HB2  . ASP B 1 224 ? 16.187  34.512  -13.782 0.33  15.133 ? 392 ASP D HB2  1 c 
ATOM   7104 H HB3  . ASP B 1 224 ? 15.607  33.116  -14.258 0.33  15.133 ? 392 ASP D HB3  1 c 
ATOM   7105 N N    . MET B 1 225 ? 19.264  32.233  -13.352 0.33  14.457 ? 393 MET D N    1 ? 
ATOM   7106 C CA   . MET B 1 225 ? 20.256  31.663  -14.247 0.33  14.735 ? 393 MET D CA   1 ? 
ATOM   7107 C C    . MET B 1 225 ? 20.027  30.163  -14.453 0.33  14.062 ? 393 MET D C    1 ? 
ATOM   7108 O O    . MET B 1 225 ? 20.47   29.617  -15.465 0.33  14.795 ? 393 MET D O    1 ? 
ATOM   7109 C CB   . MET B 1 225 ? 21.684  31.905  -13.749 0.33  15.35  ? 393 MET D CB   1 ? 
ATOM   7110 C CG   . MET B 1 225 ? 22.154  33.337  -13.97  0.33  15.138 ? 393 MET D CG   1 ? 
ATOM   7111 S SD   . MET B 1 225 ? 23.904  33.586  -13.601 0.33  16.116 ? 393 MET D SD   1 ? 
ATOM   7112 C CE   . MET B 1 225 ? 24.022  33.182  -11.857 0.33  16.038 ? 393 MET D CE   1 ? 
ATOM   7113 H H    . MET B 1 225 ? 19.502  32.454  -12.497 0.33  14.452 ? 393 MET D H    1 c 
ATOM   7114 H HA   . MET B 1 225 ? 20.149  32.105  -15.127 0.33  14.663 ? 393 MET D HA   1 c 
ATOM   7115 H HB2  . MET B 1 225 ? 21.725  31.698  -12.791 0.33  15.16  ? 393 MET D HB2  1 c 
ATOM   7116 H HB3  . MET B 1 225 ? 22.29   31.291  -14.217 0.33  15.16  ? 393 MET D HB3  1 c 
ATOM   7117 H HG2  . MET B 1 225 ? 21.994  33.586  -14.902 0.33  15.37  ? 393 MET D HG2  1 c 
ATOM   7118 H HG3  . MET B 1 225 ? 21.628  33.938  -13.406 0.33  15.37  ? 393 MET D HG3  1 c 
ATOM   7119 H HE1  . MET B 1 225 ? 24.947  33.274  -11.564 0.33  16.058 ? 393 MET D HE1  1 c 
ATOM   7120 H HE2  . MET B 1 225 ? 23.456  33.788  -11.345 0.33  16.058 ? 393 MET D HE2  1 c 
ATOM   7121 H HE3  . MET B 1 225 ? 23.726  32.263  -11.716 0.33  16.058 ? 393 MET D HE3  1 c 
ATOM   7122 N N    . TYR B 1 226 ? 19.391  29.496  -13.473 0.33  13.593 ? 394 TYR D N    1 ? 
ATOM   7123 C CA   . TYR B 1 226 ? 19.303  28.045  -13.447 0.33  13.069 ? 394 TYR D CA   1 ? 
ATOM   7124 C C    . TYR B 1 226 ? 17.836  27.594  -13.415 0.33  12.542 ? 394 TYR D C    1 ? 
ATOM   7125 O O    . TYR B 1 226 ? 17.425  26.813  -14.275 0.33  12.949 ? 394 TYR D O    1 ? 
ATOM   7126 C CB   . TYR B 1 226 ? 20.129  27.5    -12.274 0.33  13.158 ? 394 TYR D CB   1 ? 
ATOM   7127 C CG   . TYR B 1 226 ? 21.566  28.016  -12.239 0.33  13.083 ? 394 TYR D CG   1 ? 
ATOM   7128 C CD1  . TYR B 1 226 ? 22.487  27.67   -13.214 0.33  13.571 ? 394 TYR D CD1  1 ? 
ATOM   7129 C CD2  . TYR B 1 226 ? 22      28.866  -11.236 0.33  13.146 ? 394 TYR D CD2  1 ? 
ATOM   7130 C CE1  . TYR B 1 226 ? 23.784  28.17   -13.201 0.33  14.162 ? 394 TYR D CE1  1 ? 
ATOM   7131 C CE2  . TYR B 1 226 ? 23.311  29.313  -11.167 0.33  13.539 ? 394 TYR D CE2  1 ? 
ATOM   7132 C CZ   . TYR B 1 226 ? 24.203  28.981  -12.17  0.33  13.671 ? 394 TYR D CZ   1 ? 
ATOM   7133 O OH   . TYR B 1 226 ? 25.477  29.455  -12.131 0.33  13.751 ? 394 TYR D OH   1 ? 
ATOM   7134 H H    . TYR B 1 226 ? 19      29.97   -12.797 0.33  13.582 ? 394 TYR D H    1 c 
ATOM   7135 H HA   . TYR B 1 226 ? 19.708  27.703  -14.289 0.33  13.087 ? 394 TYR D HA   1 c 
ATOM   7136 H HB2  . TYR B 1 226 ? 19.681  27.747  -11.435 0.33  13.121 ? 394 TYR D HB2  1 c 
ATOM   7137 H HB3  . TYR B 1 226 ? 20.145  26.518  -12.332 0.33  13.121 ? 394 TYR D HB3  1 c 
ATOM   7138 H HD1  . TYR B 1 226 ? 22.215  27.119  -13.93  0.33  13.587 ? 394 TYR D HD1  1 c 
ATOM   7139 H HD2  . TYR B 1 226 ? 21.404  29.095  -10.542 0.33  13.232 ? 394 TYR D HD2  1 c 
ATOM   7140 H HE1  . TYR B 1 226 ? 24.394  27.914  -13.873 0.33  13.893 ? 394 TYR D HE1  1 c 
ATOM   7141 H HE2  . TYR B 1 226 ? 23.577  29.894  -10.475 0.33  13.479 ? 394 TYR D HE2  1 c 
ATOM   7142 N N    . TRP B 1 227 ? 17.064  28.058  -12.42  0.33  12.074 ? 395 TRP D N    1 ? 
ATOM   7143 C CA   . TRP B 1 227 ? 15.696  27.608  -12.189 0.33  12.12  ? 395 TRP D CA   1 ? 
ATOM   7144 C C    . TRP B 1 227 ? 14.767  28.774  -11.897 0.33  12.544 ? 395 TRP D C    1 ? 
ATOM   7145 O O    . TRP B 1 227 ? 15.041  29.562  -10.986 0.33  12.268 ? 395 TRP D O    1 ? 
ATOM   7146 C CB   . TRP B 1 227 ? 15.646  26.59   -11.037 0.33  12.121 ? 395 TRP D CB   1 ? 
ATOM   7147 C CG   . TRP B 1 227 ? 16.343  25.332  -11.45  0.33  12.041 ? 395 TRP D CG   1 ? 
ATOM   7148 C CD1  . TRP B 1 227 ? 17.646  24.998  -11.269 0.33  12.184 ? 395 TRP D CD1  1 ? 
ATOM   7149 C CD2  . TRP B 1 227 ? 15.772  24.308  -12.284 0.33  11.711 ? 395 TRP D CD2  1 ? 
ATOM   7150 N NE1  . TRP B 1 227 ? 17.924  23.818  -11.912 0.33  11.826 ? 395 TRP D NE1  1 ? 
ATOM   7151 C CE2  . TRP B 1 227 ? 16.801  23.378  -12.543 0.33  11.668 ? 395 TRP D CE2  1 ? 
ATOM   7152 C CE3  . TRP B 1 227 ? 14.499  24.11   -12.839 0.33  11.535 ? 395 TRP D CE3  1 ? 
ATOM   7153 C CZ2  . TRP B 1 227 ? 16.593  22.245  -13.322 0.33  11.595 ? 395 TRP D CZ2  1 ? 
ATOM   7154 C CZ3  . TRP B 1 227 ? 14.297  22.985  -13.598 0.33  11.476 ? 395 TRP D CZ3  1 ? 
ATOM   7155 C CH2  . TRP B 1 227 ? 15.333  22.097  -13.855 0.33  12.061 ? 395 TRP D CH2  1 ? 
ATOM   7156 H H    . TRP B 1 227 ? 17.412  28.689  -11.857 0.33  12.194 ? 395 TRP D H    1 c 
ATOM   7157 H HA   . TRP B 1 227 ? 15.378  27.154  -13.016 0.33  12.188 ? 395 TRP D HA   1 c 
ATOM   7158 H HB2  . TRP B 1 227 ? 16.096  26.97   -10.253 0.33  12.102 ? 395 TRP D HB2  1 c 
ATOM   7159 H HB3  . TRP B 1 227 ? 14.709  26.389  -10.826 0.33  12.102 ? 395 TRP D HB3  1 c 
ATOM   7160 H HD1  . TRP B 1 227 ? 18.275  25.497  -10.773 0.33  12.062 ? 395 TRP D HD1  1 c 
ATOM   7161 H HE1  . TRP B 1 227 ? 18.694  23.406  -11.9   0.33  11.871 ? 395 TRP D HE1  1 c 
ATOM   7162 H HE3  . TRP B 1 227 ? 13.798  24.716  -12.669 0.33  11.568 ? 395 TRP D HE3  1 c 
ATOM   7163 H HZ2  . TRP B 1 227 ? 17.286  21.633  -13.503 0.33  11.718 ? 395 TRP D HZ2  1 c 
ATOM   7164 H HZ3  . TRP B 1 227 ? 13.45   22.832  -13.983 0.33  11.626 ? 395 TRP D HZ3  1 c 
ATOM   7165 H HH2  . TRP B 1 227 ? 15.157  21.352  -14.377 0.33  11.808 ? 395 TRP D HH2  1 c 
ATOM   7166 N N    . SER B 1 228 ? 13.666  28.845  -12.669 0.33  12.597 ? 396 SER D N    1 ? 
ATOM   7167 C CA   . SER B 1 228 ? 12.674  29.902  -12.554 0.33  13.163 ? 396 SER D CA   1 ? 
ATOM   7168 C C    . SER B 1 228 ? 11.318  29.286  -12.238 0.33  13.115 ? 396 SER D C    1 ? 
ATOM   7169 O O    . SER B 1 228 ? 10.654  28.766  -13.131 0.33  12.819 ? 396 SER D O    1 ? 
ATOM   7170 C CB   . SER B 1 228 ? 12.593  30.742  -13.802 0.33  14.016 ? 396 SER D CB   1 ? 
ATOM   7171 O OG   . SER B 1 228 ? 13.89   31.119  -14.241 0.33  16.307 ? 396 SER D OG   1 ? 
ATOM   7172 H H    . SER B 1 228 ? 13.534  28.195  -13.298 0.33  12.71  ? 396 SER D H    1 c 
ATOM   7173 H HA   . SER B 1 228 ? 12.933  30.488  -11.798 0.33  13.195 ? 396 SER D HA   1 c 
ATOM   7174 H HB2  . SER B 1 228 ? 12.146  30.235  -14.506 0.33  14.326 ? 396 SER D HB2  1 c 
ATOM   7175 H HB3  . SER B 1 228 ? 12.066  31.543  -13.62  0.33  14.326 ? 396 SER D HB3  1 c 
ATOM   7176 N N    . ASP B 1 229 ? 10.931  29.338  -10.962 0.33  13.478 ? 397 ASP D N    1 ? 
ATOM   7177 C CA   . ASP B 1 229 ? 9.709   28.723  -10.463 0.33  14.634 ? 397 ASP D CA   1 ? 
ATOM   7178 C C    . ASP B 1 229 ? 9.671   27.253  -10.901 0.33  14.626 ? 397 ASP D C    1 ? 
ATOM   7179 O O    . ASP B 1 229 ? 8.679   26.773  -11.458 0.33  13.147 ? 397 ASP D O    1 ? 
ATOM   7180 C CB   . ASP B 1 229 ? 8.484   29.54   -10.857 0.33  16.489 ? 397 ASP D CB   1 ? 
ATOM   7181 C CG   . ASP B 1 229 ? 8.445   30.994  -10.405 0.33  19.655 ? 397 ASP D CG   1 ? 
ATOM   7182 O OD1  . ASP B 1 229 ? 9.146   31.347  -9.435  0.33  20.4   ? 397 ASP D OD1  1 ? 
ATOM   7183 O OD2  . ASP B 1 229 ? 7.738   31.787  -11.063 0.33  26.421 ? 397 ASP D OD2  1 ? 
ATOM   7184 H H    . ASP B 1 229 ? 11.462  29.785  -10.367 0.33  13.643 ? 397 ASP D H    1 c 
ATOM   7185 H HA   . ASP B 1 229 ? 9.747   28.742  -9.48   0.33  14.728 ? 397 ASP D HA   1 c 
ATOM   7186 H HB2  . ASP B 1 229 ? 8.41    29.528  -11.834 0.33  16.708 ? 397 ASP D HB2  1 c 
ATOM   7187 H HB3  . ASP B 1 229 ? 7.69    29.093  -10.495 0.33  16.708 ? 397 ASP D HB3  1 c 
ATOM   7188 N N    . ASP B 1 230 ? 10.793  26.558  -10.662 0.33  13.301 ? 398 ASP D N    1 ? 
ATOM   7189 C CA   . ASP B 1 230 ? 10.975  25.141  -10.944 0.33  13.33  ? 398 ASP D CA   1 ? 
ATOM   7190 C C    . ASP B 1 230 ? 10.941  24.832  -12.439 0.33  13.552 ? 398 ASP D C    1 ? 
ATOM   7191 O O    . ASP B 1 230 ? 10.736  23.678  -12.804 0.33  13.618 ? 398 ASP D O    1 ? 
ATOM   7192 C CB   . ASP B 1 230 ? 10.037  24.264  -10.122 0.33  12.809 ? 398 ASP D CB   1 ? 
ATOM   7193 C CG   . ASP B 1 230 ? 10.515  24.045  -8.697  0.33  12.001 ? 398 ASP D CG   1 ? 
ATOM   7194 O OD1  . ASP B 1 230 ? 11.577  23.408  -8.516  0.33  12.085 ? 398 ASP D OD1  1 ? 
ATOM   7195 O OD2  . ASP B 1 230 ? 9.867   24.56   -7.801  0.33  10.41  ? 398 ASP D OD2  1 ? 
ATOM   7196 H H    . ASP B 1 230 ? 11.498  27.01   -10.294 0.33  13.612 ? 398 ASP D H    1 c 
ATOM   7197 H HA   . ASP B 1 230 ? 11.873  24.899  -10.624 0.33  13.264 ? 398 ASP D HA   1 c 
ATOM   7198 H HB2  . ASP B 1 230 ? 9.151   24.682  -10.093 0.33  12.734 ? 398 ASP D HB2  1 c 
ATOM   7199 H HB3  . ASP B 1 230 ? 9.95    23.391  -10.559 0.33  12.734 ? 398 ASP D HB3  1 c 
ATOM   7200 N N    . VAL B 1 231 ? 11.207  25.835  -13.288 0.33  14.202 ? 399 VAL D N    1 ? 
ATOM   7201 C CA   . VAL B 1 231 ? 11.354  25.654  -14.725 0.33  15.505 ? 399 VAL D CA   1 ? 
ATOM   7202 C C    . VAL B 1 231 ? 12.779  26.016  -15.139 0.33  15.123 ? 399 VAL D C    1 ? 
ATOM   7203 O O    . VAL B 1 231 ? 13.301  27.06   -14.743 0.33  13.854 ? 399 VAL D O    1 ? 
ATOM   7204 C CB   . VAL B 1 231 ? 10.334  26.523  -15.481 0.33  15.387 ? 399 VAL D CB   1 ? 
ATOM   7205 C CG1  . VAL B 1 231 ? 10.524  26.426  -16.99  0.33  15.942 ? 399 VAL D CG1  1 ? 
ATOM   7206 C CG2  . VAL B 1 231 ? 8.903   26.165  -15.091 0.33  15.109 ? 399 VAL D CG2  1 ? 
ATOM   7207 H H    . VAL B 1 231 ? 11.302  26.678  -12.947 0.33  14.326 ? 399 VAL D H    1 c 
ATOM   7208 H HA   . VAL B 1 231 ? 11.191  24.715  -14.94  0.33  15.15  ? 399 VAL D HA   1 c 
ATOM   7209 H HB   . VAL B 1 231 ? 10.495  27.458  -15.215 0.33  15.458 ? 399 VAL D HB   1 c 
ATOM   7210 H HG11 . VAL B 1 231 ? 10.408  25.504  -17.274 0.33  15.776 ? 399 VAL D HG11 1 c 
ATOM   7211 H HG12 . VAL B 1 231 ? 11.418  26.726  -17.225 0.33  15.776 ? 399 VAL D HG12 1 c 
ATOM   7212 H HG13 . VAL B 1 231 ? 9.868   26.987  -17.437 0.33  15.776 ? 399 VAL D HG13 1 c 
ATOM   7213 H HG21 . VAL B 1 231 ? 8.282   26.724  -15.587 0.33  15.19  ? 399 VAL D HG21 1 c 
ATOM   7214 H HG22 . VAL B 1 231 ? 8.78    26.311  -14.138 0.33  15.19  ? 399 VAL D HG22 1 c 
ATOM   7215 H HG23 . VAL B 1 231 ? 8.734   25.231  -15.3   0.33  15.19  ? 399 VAL D HG23 1 c 
ATOM   7216 N N    . ALA B 1 232 ? 13.411  25.118  -15.907 0.33  14.362 ? 400 ALA D N    1 ? 
ATOM   7217 C CA   . ALA B 1 232 ? 14.803  25.281  -16.284 0.33  15.033 ? 400 ALA D CA   1 ? 
ATOM   7218 C C    . ALA B 1 232 ? 15.012  26.519  -17.153 0.33  15.044 ? 400 ALA D C    1 ? 
ATOM   7219 O O    . ALA B 1 232 ? 14.259  26.768  -18.089 0.33  13.858 ? 400 ALA D O    1 ? 
ATOM   7220 C CB   . ALA B 1 232 ? 15.284  24.033  -16.999 0.33  15.63  ? 400 ALA D CB   1 ? 
ATOM   7221 H H    . ALA B 1 232 ? 12.957  24.382  -16.203 0.33  14.69  ? 400 ALA D H    1 c 
ATOM   7222 H HA   . ALA B 1 232 ? 15.335  25.399  -15.449 0.33  15.008 ? 400 ALA D HA   1 c 
ATOM   7223 H HB1  . ALA B 1 232 ? 15.202  23.266  -16.408 0.33  15.451 ? 400 ALA D HB1  1 c 
ATOM   7224 H HB2  . ALA B 1 232 ? 14.747  23.884  -17.795 0.33  15.451 ? 400 ALA D HB2  1 c 
ATOM   7225 H HB3  . ALA B 1 232 ? 16.215  24.142  -17.255 0.33  15.451 ? 400 ALA D HB3  1 c 
ATOM   7226 N N    . CYS B 1 233 ? 16.049  27.288  -16.814 0.33  15.38  ? 401 CYS D N    1 ? 
ATOM   7227 C CA   . CYS B 1 233 ? 16.539  28.342  -17.682 0.33  18.274 ? 401 CYS D CA   1 ? 
ATOM   7228 C C    . CYS B 1 233 ? 17.473  27.689  -18.696 0.33  17.831 ? 401 CYS D C    1 ? 
ATOM   7229 O O    . CYS B 1 233 ? 18.682  27.632  -18.489 0.33  16.551 ? 401 CYS D O    1 ? 
ATOM   7230 C CB   . CYS B 1 233 ? 17.231  29.433  -16.863 0.33  20.18  ? 401 CYS D CB   1 ? 
ATOM   7231 S SG   . CYS B 1 233 ? 17.272  31.071  -17.636 0.33  24.136 ? 401 CYS D SG   1 ? 
ATOM   7232 H H    . CYS B 1 233 ? 16.466  27.148  -16.012 0.33  15.908 ? 401 CYS D H    1 c 
ATOM   7233 H HA   . CYS B 1 233 ? 15.766  28.731  -18.165 0.33  17.905 ? 401 CYS D HA   1 c 
ATOM   7234 H HB2  . CYS B 1 233 ? 16.773  29.516  -15.997 0.33  20.393 ? 401 CYS D HB2  1 c 
ATOM   7235 H HB3  . CYS B 1 233 ? 18.157  29.156  -16.685 0.33  20.393 ? 401 CYS D HB3  1 c 
ATOM   7236 N N    . ASP B 1 234 ? 16.892  27.161  -19.779 0.33  19.833 ? 402 ASP D N    1 ? 
ATOM   7237 C CA   . ASP B 1 234 ? 17.648  26.364  -20.732 0.33  22.538 ? 402 ASP D CA   1 ? 
ATOM   7238 C C    . ASP B 1 234 ? 17.634  27.015  -22.119 0.33  24.966 ? 402 ASP D C    1 ? 
ATOM   7239 O O    . ASP B 1 234 ? 17.862  26.338  -23.118 0.33  24.509 ? 402 ASP D O    1 ? 
ATOM   7240 C CB   . ASP B 1 234 ? 17.126  24.937  -20.775 0.33  23.588 ? 402 ASP D CB   1 ? 
ATOM   7241 C CG   . ASP B 1 234 ? 15.652  24.8    -21.138 0.33  23.693 ? 402 ASP D CG   1 ? 
ATOM   7242 O OD1  . ASP B 1 234 ? 15.027  25.808  -21.493 0.33  25.25  ? 402 ASP D OD1  1 ? 
ATOM   7243 O OD2  . ASP B 1 234 ? 15.138  23.685  -21.056 0.33  25.616 ? 402 ASP D OD2  1 ? 
ATOM   7244 H H    . ASP B 1 234 ? 16.001  27.302  -19.926 0.33  19.9   ? 402 ASP D H    1 c 
ATOM   7245 H HA   . ASP B 1 234 ? 18.581  26.324  -20.42  0.33  22.589 ? 402 ASP D HA   1 c 
ATOM   7246 H HB2  . ASP B 1 234 ? 17.65   24.431  -21.431 0.33  23.368 ? 402 ASP D HB2  1 c 
ATOM   7247 H HB3  . ASP B 1 234 ? 17.264  24.525  -19.897 0.33  23.368 ? 402 ASP D HB3  1 c 
ATOM   7248 N N    . GLU B 1 235 ? 17.381  28.328  -22.169 0.33  27.975 ? 403 GLU D N    1 ? 
ATOM   7249 C CA   . GLU B 1 235 ? 17.316  29.059  -23.422 0.33  31.31  ? 403 GLU D CA   1 ? 
ATOM   7250 C C    . GLU B 1 235 ? 18.65   29.752  -23.693 0.33  32.779 ? 403 GLU D C    1 ? 
ATOM   7251 O O    . GLU B 1 235 ? 19.538  29.772  -22.84  0.33  31.836 ? 403 GLU D O    1 ? 
ATOM   7252 C CB   . GLU B 1 235 ? 16.177  30.077  -23.389 0.33  35.562 ? 403 GLU D CB   1 ? 
ATOM   7253 C CG   . GLU B 1 235 ? 14.79   29.439  -23.37  0.33  38.844 ? 403 GLU D CG   1 ? 
ATOM   7254 C CD   . GLU B 1 235 ? 13.639  30.367  -23.716 0.33  43.349 ? 403 GLU D CD   1 ? 
ATOM   7255 O OE1  . GLU B 1 235 ? 13.897  31.455  -24.285 0.33  47.108 ? 403 GLU D OE1  1 ? 
ATOM   7256 O OE2  . GLU B 1 235 ? 12.478  30.004  -23.409 0.33  44.077 ? 403 GLU D OE2  1 ? 
ATOM   7257 H H    . GLU B 1 235 ? 17.245  28.784  -21.388 0.33  27.928 ? 403 GLU D H    1 c 
ATOM   7258 H HA   . GLU B 1 235 ? 17.144  28.411  -24.151 0.33  31.611 ? 403 GLU D HA   1 c 
ATOM   7259 H HB2  . GLU B 1 235 ? 16.279  30.64   -22.594 0.33  35.246 ? 403 GLU D HB2  1 c 
ATOM   7260 H HB3  . GLU B 1 235 ? 16.249  30.657  -24.176 0.33  35.246 ? 403 GLU D HB3  1 c 
ATOM   7261 H HG2  . GLU B 1 235 ? 14.78   28.688  -24.001 0.33  39.046 ? 403 GLU D HG2  1 c 
ATOM   7262 H HG3  . GLU B 1 235 ? 14.627  29.068  -22.476 0.33  39.046 ? 403 GLU D HG3  1 c 
ATOM   7263 N N    . GLY B 1 236 ? 18.776  30.317  -24.901 0.33  30.617 ? 404 GLY D N    1 ? 
ATOM   7264 C CA   . GLY B 1 236 ? 19.992  31.01   -25.289 0.33  30.485 ? 404 GLY D CA   1 ? 
ATOM   7265 C C    . GLY B 1 236 ? 20.257  32.189  -24.36  0.33  28.162 ? 404 GLY D C    1 ? 
ATOM   7266 O O    . GLY B 1 236 ? 21.391  32.441  -23.95  0.33  26.15  ? 404 GLY D O    1 ? 
ATOM   7267 H H    . GLY B 1 236 ? 18.085  30.267  -25.496 0.33  31.089 ? 404 GLY D H    1 c 
ATOM   7268 H HA2  . GLY B 1 236 ? 20.75   30.381  -25.255 0.33  29.983 ? 404 GLY D HA2  1 c 
ATOM   7269 H HA3  . GLY B 1 236 ? 19.901  31.331  -26.217 0.33  29.983 ? 404 GLY D HA3  1 c 
ATOM   7270 N N    . TRP B 1 237 ? 19.19   32.911  -24.02  0.33  29.032 ? 405 TRP D N    1 ? 
ATOM   7271 C CA   . TRP B 1 237 ? 19.349  34.086  -23.182 0.33  29.523 ? 405 TRP D CA   1 ? 
ATOM   7272 C C    . TRP B 1 237 ? 19.892  33.68   -21.813 0.33  26.408 ? 405 TRP D C    1 ? 
ATOM   7273 O O    . TRP B 1 237 ? 20.647  34.436  -21.199 0.33  26.792 ? 405 TRP D O    1 ? 
ATOM   7274 C CB   . TRP B 1 237 ? 18.044  34.895  -23.097 0.33  32.362 ? 405 TRP D CB   1 ? 
ATOM   7275 C CG   . TRP B 1 237 ? 16.875  34.248  -22.4   0.33  34.174 ? 405 TRP D CG   1 ? 
ATOM   7276 C CD1  . TRP B 1 237 ? 15.845  33.556  -22.974 0.33  35.538 ? 405 TRP D CD1  1 ? 
ATOM   7277 C CD2  . TRP B 1 237 ? 16.571  34.315  -20.989 0.33  35.829 ? 405 TRP D CD2  1 ? 
ATOM   7278 N NE1  . TRP B 1 237 ? 14.942  33.164  -22.021 0.33  35.325 ? 405 TRP D NE1  1 ? 
ATOM   7279 C CE2  . TRP B 1 237 ? 15.356  33.619  -20.796 0.33  35.798 ? 405 TRP D CE2  1 ? 
ATOM   7280 C CE3  . TRP B 1 237 ? 17.206  34.886  -19.882 0.33  36.106 ? 405 TRP D CE3  1 ? 
ATOM   7281 C CZ2  . TRP B 1 237 ? 14.773  33.481  -19.539 0.33  35.91  ? 405 TRP D CZ2  1 ? 
ATOM   7282 C CZ3  . TRP B 1 237 ? 16.62   34.761  -18.641 0.33  37.847 ? 405 TRP D CZ3  1 ? 
ATOM   7283 C CH2  . TRP B 1 237 ? 15.421  34.069  -18.475 0.33  37.976 ? 405 TRP D CH2  1 ? 
ATOM   7284 H H    . TRP B 1 237 ? 18.357  32.672  -24.309 0.33  28.93  ? 405 TRP D H    1 c 
ATOM   7285 H HA   . TRP B 1 237 ? 20.03   34.668  -23.615 0.33  29.317 ? 405 TRP D HA   1 c 
ATOM   7286 H HB2  . TRP B 1 237 ? 18.242  35.744  -22.647 0.33  32.099 ? 405 TRP D HB2  1 c 
ATOM   7287 H HB3  . TRP B 1 237 ? 17.771  35.126  -24.01  0.33  32.099 ? 405 TRP D HB3  1 c 
ATOM   7288 H HD1  . TRP B 1 237 ? 15.768  33.358  -23.893 0.33  35.17  ? 405 TRP D HD1  1 c 
ATOM   7289 H HE1  . TRP B 1 237 ? 14.219  32.7    -22.172 0.33  35.475 ? 405 TRP D HE1  1 c 
ATOM   7290 H HE3  . TRP B 1 237 ? 18.015  35.357  -19.986 0.33  36.437 ? 405 TRP D HE3  1 c 
ATOM   7291 H HZ2  . TRP B 1 237 ? 13.958  33.022  -19.426 0.33  36.356 ? 405 TRP D HZ2  1 c 
ATOM   7292 H HZ3  . TRP B 1 237 ? 17.043  35.141  -17.888 0.33  37.421 ? 405 TRP D HZ3  1 c 
ATOM   7293 H HH2  . TRP B 1 237 ? 15.049  33.994  -17.614 0.33  37.412 ? 405 TRP D HH2  1 c 
ATOM   7294 N N    . CYS B 1 238 ? 19.554  32.458  -21.375 0.33  25.604 ? 406 CYS D N    1 ? 
ATOM   7295 C CA   . CYS B 1 238 ? 20.019  31.926  -20.102 0.33  24.578 ? 406 CYS D CA   1 ? 
ATOM   7296 C C    . CYS B 1 238 ? 21.537  31.747  -20.127 0.33  23.939 ? 406 CYS D C    1 ? 
ATOM   7297 O O    . CYS B 1 238 ? 22.249  32.117  -19.191 0.33  22.894 ? 406 CYS D O    1 ? 
ATOM   7298 C CB   . CYS B 1 238 ? 19.314  30.611  -19.781 0.33  24.111 ? 406 CYS D CB   1 ? 
ATOM   7299 S SG   . CYS B 1 238 ? 17.516  30.765  -19.648 0.33  25.714 ? 406 CYS D SG   1 ? 
ATOM   7300 H H    . CYS B 1 238 ? 19.01   31.937  -21.894 0.33  25.557 ? 406 CYS D H    1 c 
ATOM   7301 H HA   . CYS B 1 238 ? 19.794  32.584  -19.396 0.33  24.57  ? 406 CYS D HA   1 c 
ATOM   7302 H HB2  . CYS B 1 238 ? 19.519  29.956  -20.485 0.33  24.519 ? 406 CYS D HB2  1 c 
ATOM   7303 H HB3  . CYS B 1 238 ? 19.66   30.26   -18.93  0.33  24.519 ? 406 CYS D HB3  1 c 
ATOM   7304 N N    . GLU B 1 239 ? 22.026  31.129  -21.202 0.33  24.02  ? 407 GLU D N    1 ? 
ATOM   7305 C CA   . GLU B 1 239 ? 23.439  30.833  -21.322 0.33  24.005 ? 407 GLU D CA   1 ? 
ATOM   7306 C C    . GLU B 1 239 ? 24.253  32.124  -21.383 0.33  21.52  ? 407 GLU D C    1 ? 
ATOM   7307 O O    . GLU B 1 239 ? 25.318  32.198  -20.784 0.33  21.668 ? 407 GLU D O    1 ? 
ATOM   7308 C CB   . GLU B 1 239 ? 23.686  30      -22.575 0.33  28.712 ? 407 GLU D CB   1 ? 
ATOM   7309 C CG   . GLU B 1 239 ? 25.161  29.677  -22.764 0.33  31.613 ? 407 GLU D CG   1 ? 
ATOM   7310 C CD   . GLU B 1 239 ? 25.407  28.351  -23.458 0.33  38.443 ? 407 GLU D CD   1 ? 
ATOM   7311 O OE1  . GLU B 1 239 ? 24.456  27.567  -23.688 0.33  39.584 ? 407 GLU D OE1  1 ? 
ATOM   7312 O OE2  . GLU B 1 239 ? 26.59   28.102  -23.776 0.33  43.027 ? 407 GLU D OE2  1 ? 
ATOM   7313 H H    . GLU B 1 239 ? 21.463  30.885  -21.879 0.33  23.998 ? 407 GLU D H    1 c 
ATOM   7314 H HA   . GLU B 1 239 ? 23.72   30.315  -20.525 0.33  24.316 ? 407 GLU D HA   1 c 
ATOM   7315 H HB2  . GLU B 1 239 ? 23.175  29.166  -22.509 0.33  28.171 ? 407 GLU D HB2  1 c 
ATOM   7316 H HB3  . GLU B 1 239 ? 23.357  30.493  -23.355 0.33  28.171 ? 407 GLU D HB3  1 c 
ATOM   7317 H HG2  . GLU B 1 239 ? 25.58   30.389  -23.293 0.33  32.353 ? 407 GLU D HG2  1 c 
ATOM   7318 H HG3  . GLU B 1 239 ? 25.6    29.657  -21.887 0.33  32.353 ? 407 GLU D HG3  1 c 
ATOM   7319 N N    . GLU B 1 240 ? 23.752  33.127  -22.113 0.33  20.942 ? 408 GLU D N    1 ? 
ATOM   7320 C CA   . GLU B 1 240 ? 24.404  34.425  -22.222 0.33  21.42  ? 408 GLU D CA   1 ? 
ATOM   7321 C C    . GLU B 1 240 ? 24.524  35.073  -20.841 0.33  21.648 ? 408 GLU D C    1 ? 
ATOM   7322 O O    . GLU B 1 240 ? 25.568  35.647  -20.516 0.33  20.603 ? 408 GLU D O    1 ? 
ATOM   7323 C CB   . GLU B 1 240 ? 23.634  35.327  -23.186 0.33  23.345 ? 408 GLU D CB   1 ? 
ATOM   7324 C CG   . GLU B 1 240 ? 24.153  36.763  -23.254 0.33  26.128 ? 408 GLU D CG   1 ? 
ATOM   7325 C CD   . GLU B 1 240 ? 23.177  37.761  -23.858 0.33  29.53  ? 408 GLU D CD   1 ? 
ATOM   7326 O OE1  . GLU B 1 240 ? 22.205  37.324  -24.523 0.33  30.762 ? 408 GLU D OE1  1 ? 
ATOM   7327 O OE2  . GLU B 1 240 ? 23.367  38.986  -23.645 0.33  30.479 ? 408 GLU D OE2  1 ? 
ATOM   7328 H H    . GLU B 1 240 ? 22.968  32.994  -22.564 0.33  21.186 ? 408 GLU D H    1 c 
ATOM   7329 H HA   . GLU B 1 240 ? 25.317  34.283  -22.582 0.33  21.705 ? 408 GLU D HA   1 c 
ATOM   7330 H HB2  . GLU B 1 240 ? 23.676  34.936  -24.083 0.33  23.487 ? 408 GLU D HB2  1 c 
ATOM   7331 H HB3  . GLU B 1 240 ? 22.693  35.347  -22.914 0.33  23.487 ? 408 GLU D HB3  1 c 
ATOM   7332 H HG2  . GLU B 1 240 ? 24.381  37.062  -22.347 0.33  26.195 ? 408 GLU D HG2  1 c 
ATOM   7333 H HG3  . GLU B 1 240 ? 24.979  36.777  -23.784 0.33  26.195 ? 408 GLU D HG3  1 c 
ATOM   7334 N N    . ASN B 1 241 ? 23.453  34.959  -20.034 0.33  20.724 ? 409 ASN D N    1 ? 
ATOM   7335 C CA   . ASN B 1 241 ? 23.458  35.503  -18.68  0.33  19.809 ? 409 ASN D CA   1 ? 
ATOM   7336 C C    . ASN B 1 241 ? 24.536  34.819  -17.842 0.33  18.906 ? 409 ASN D C    1 ? 
ATOM   7337 O O    . ASN B 1 241 ? 25.23   35.48   -17.074 0.33  17.358 ? 409 ASN D O    1 ? 
ATOM   7338 C CB   . ASN B 1 241 ? 22.102  35.388  -17.986 0.33  21.118 ? 409 ASN D CB   1 ? 
ATOM   7339 C CG   . ASN B 1 241 ? 21.117  36.435  -18.437 0.33  20.973 ? 409 ASN D CG   1 ? 
ATOM   7340 O OD1  . ASN B 1 241 ? 21.491  37.403  -19.11  0.33  21.053 ? 409 ASN D OD1  1 ? 
ATOM   7341 N ND2  . ASN B 1 241 ? 19.859  36.279  -18.049 0.33  21.447 ? 409 ASN D ND2  1 ? 
ATOM   7342 H H    . ASN B 1 241 ? 22.704  34.533  -20.338 0.33  20.73  ? 409 ASN D H    1 c 
ATOM   7343 H HA   . ASN B 1 241 ? 23.676  36.461  -18.739 0.33  20.05  ? 409 ASN D HA   1 c 
ATOM   7344 H HB2  . ASN B 1 241 ? 21.728  34.502  -18.165 0.33  20.781 ? 409 ASN D HB2  1 c 
ATOM   7345 H HB3  . ASN B 1 241 ? 22.232  35.469  -17.02  0.33  20.781 ? 409 ASN D HB3  1 c 
ATOM   7346 H HD21 . ASN B 1 241 ? 19.243  36.866  -18.298 0.33  21.3   ? 409 ASN D HD21 1 c 
ATOM   7347 H HD22 . ASN B 1 241 ? 19.636  35.587  -17.54  0.33  21.3   ? 409 ASN D HD22 1 c 
ATOM   7348 N N    . ARG B 1 242 ? 24.686  33.497  -17.992 0.33  17.616 ? 410 ARG D N    1 ? 
ATOM   7349 C CA   . ARG B 1 242 ? 25.631  32.74   -17.188 0.33  17.834 ? 410 ARG D CA   1 ? 
ATOM   7350 C C    . ARG B 1 242 ? 27.069  33.099  -17.575 0.33  17.901 ? 410 ARG D C    1 ? 
ATOM   7351 O O    . ARG B 1 242 ? 27.936  33.179  -16.706 0.33  17.396 ? 410 ARG D O    1 ? 
ATOM   7352 C CB   . ARG B 1 242 ? 25.348  31.233  -17.3   0.33  18.077 ? 410 ARG D CB   1 ? 
ATOM   7353 C CG   . ARG B 1 242 ? 24.102  30.794  -16.537 0.33  18.323 ? 410 ARG D CG   1 ? 
ATOM   7354 C CD   . ARG B 1 242 ? 23.861  29.283  -16.449 0.33  19.152 ? 410 ARG D CD   1 ? 
ATOM   7355 N NE   . ARG B 1 242 ? 23.744  28.641  -17.765 0.33  19.487 ? 410 ARG D NE   1 ? 
ATOM   7356 C CZ   . ARG B 1 242 ? 22.621  28.382  -18.415 0.33  19.474 ? 410 ARG D CZ   1 ? 
ATOM   7357 N NH1  . ARG B 1 242 ? 21.455  28.724  -17.902 0.33  21.12  ? 410 ARG D NH1  1 ? 
ATOM   7358 N NH2  . ARG B 1 242 ? 22.67   27.782  -19.591 0.33  19.008 ? 410 ARG D NH2  1 ? 
ATOM   7359 H H    . ARG B 1 242 ? 24.184  33.057  -18.616 0.33  17.965 ? 410 ARG D H    1 c 
ATOM   7360 H HA   . ARG B 1 242 ? 25.497  33      -16.242 0.33  17.848 ? 410 ARG D HA   1 c 
ATOM   7361 H HB2  . ARG B 1 242 ? 25.239  30.999  -18.246 0.33  18.078 ? 410 ARG D HB2  1 c 
ATOM   7362 H HB3  . ARG B 1 242 ? 26.122  30.738  -16.955 0.33  18.078 ? 410 ARG D HB3  1 c 
ATOM   7363 H HG2  . ARG B 1 242 ? 24.155  31.152  -15.624 0.33  18.451 ? 410 ARG D HG2  1 c 
ATOM   7364 H HG3  . ARG B 1 242 ? 23.318  31.208  -16.958 0.33  18.451 ? 410 ARG D HG3  1 c 
ATOM   7365 H HD2  . ARG B 1 242 ? 24.601  28.872  -15.957 0.33  19.041 ? 410 ARG D HD2  1 c 
ATOM   7366 H HD3  . ARG B 1 242 ? 23.039  29.123  -15.941 0.33  19.041 ? 410 ARG D HD3  1 c 
ATOM   7367 H HE   . ARG B 1 242 ? 24.483  28.405  -18.16  0.33  19.406 ? 410 ARG D HE   1 c 
ATOM   7368 H HH11 . ARG B 1 242 ? 21.423  29.126  -17.115 0.33  20.599 ? 410 ARG D HH11 1 c 
ATOM   7369 H HH12 . ARG B 1 242 ? 20.712  28.549  -18.347 0.33  20.599 ? 410 ARG D HH12 1 c 
ATOM   7370 H HH21 . ARG B 1 242 ? 23.452  27.559  -19.939 0.33  19.15  ? 410 ARG D HH21 1 c 
ATOM   7371 H HH22 . ARG B 1 242 ? 21.92   27.606  -20.026 0.33  19.15  ? 410 ARG D HH22 1 c 
ATOM   7372 N N    . THR B 1 243 ? 27.309  33.296  -18.882 0.33  20.039 ? 411 THR D N    1 ? 
ATOM   7373 C CA   . THR B 1 243 ? 28.632  33.639  -19.395 0.33  20.024 ? 411 THR D CA   1 ? 
ATOM   7374 C C    . THR B 1 243 ? 29.024  35.033  -18.912 0.33  18.741 ? 411 THR D C    1 ? 
ATOM   7375 O O    . THR B 1 243 ? 30.168  35.285  -18.567 0.33  17.54  ? 411 THR D O    1 ? 
ATOM   7376 C CB   . THR B 1 243 ? 28.645  33.652  -20.925 0.33  21.624 ? 411 THR D CB   1 ? 
ATOM   7377 O OG1  . THR B 1 243 ? 28.157  32.434  -21.478 0.33  21.641 ? 411 THR D OG1  1 ? 
ATOM   7378 C CG2  . THR B 1 243 ? 30.03   33.931  -21.481 0.33  21.297 ? 411 THR D CG2  1 ? 
ATOM   7379 H H    . THR B 1 243 ? 26.619  33.213  -19.475 0.33  19.504 ? 411 THR D H    1 c 
ATOM   7380 H HA   . THR B 1 243 ? 29.285  32.983  -19.069 0.33  20.066 ? 411 THR D HA   1 c 
ATOM   7381 H HB   . THR B 1 243 ? 28.058  34.386  -21.225 0.33  21.264 ? 411 THR D HB   1 c 
ATOM   7382 H HG21 . THR B 1 243 ? 30.002  33.9    -22.452 0.33  21.393 ? 411 THR D HG21 1 c 
ATOM   7383 H HG22 . THR B 1 243 ? 30.652  33.26   -21.154 0.33  21.393 ? 411 THR D HG22 1 c 
ATOM   7384 H HG23 . THR B 1 243 ? 30.323  34.812  -21.195 0.33  21.393 ? 411 THR D HG23 1 c 
ATOM   7385 N N    . ASN B 1 244 ? 28.055  35.942  -18.93  0.33  19.205 ? 412 ASN D N    1 ? 
ATOM   7386 C CA   . ASN B 1 244 ? 28.334  37.318  -18.568 0.33  20.079 ? 412 ASN D CA   1 ? 
ATOM   7387 C C    . ASN B 1 244 ? 28.564  37.423  -17.063 0.33  19.811 ? 412 ASN D C    1 ? 
ATOM   7388 O O    . ASN B 1 244 ? 29.429  38.181  -16.63  0.33  18.981 ? 412 ASN D O    1 ? 
ATOM   7389 C CB   . ASN B 1 244 ? 27.28   38.256  -19.134 0.33  19.984 ? 412 ASN D CB   1 ? 
ATOM   7390 C CG   . ASN B 1 244 ? 27.464  38.487  -20.615 0.33  20.33  ? 412 ASN D CG   1 ? 
ATOM   7391 O OD1  . ASN B 1 244 ? 28.599  38.532  -21.096 0.33  22.631 ? 412 ASN D OD1  1 ? 
ATOM   7392 N ND2  . ASN B 1 244 ? 26.376  38.666  -21.345 0.33  20.475 ? 412 ASN D ND2  1 ? 
ATOM   7393 H H    . ASN B 1 244 ? 27.205  35.705  -19.172 0.33  19.285 ? 412 ASN D H    1 c 
ATOM   7394 H HA   . ASN B 1 244 ? 29.183  37.562  -19.003 0.33  19.84  ? 412 ASN D HA   1 c 
ATOM   7395 H HB2  . ASN B 1 244 ? 26.394  37.875  -18.976 0.33  20.085 ? 412 ASN D HB2  1 c 
ATOM   7396 H HB3  . ASN B 1 244 ? 27.329  39.114  -18.667 0.33  20.085 ? 412 ASN D HB3  1 c 
ATOM   7397 H HD21 . ASN B 1 244 ? 26.447  38.797  -22.219 0.33  20.43  ? 412 ASN D HD21 1 c 
ATOM   7398 H HD22 . ASN B 1 244 ? 25.578  38.656  -20.959 0.33  20.43  ? 412 ASN D HD22 1 c 
ATOM   7399 N N    . ALA B 1 245 ? 27.811  36.64   -16.272 0.33  20.214 ? 413 ALA D N    1 ? 
ATOM   7400 C CA   . ALA B 1 245 ? 28.05   36.564  -14.839 0.33  19.787 ? 413 ALA D CA   1 ? 
ATOM   7401 C C    . ALA B 1 245 ? 29.456  36.046  -14.557 0.33  19.037 ? 413 ALA D C    1 ? 
ATOM   7402 O O    . ALA B 1 245 ? 30.094  36.513  -13.616 0.33  17.766 ? 413 ALA D O    1 ? 
ATOM   7403 C CB   . ALA B 1 245 ? 27.022  35.685  -14.152 0.33  19.916 ? 413 ALA D CB   1 ? 
ATOM   7404 H H    . ALA B 1 245 ? 27.134  36.145  -16.636 0.33  20.021 ? 413 ALA D H    1 c 
ATOM   7405 H HA   . ALA B 1 245 ? 27.983  37.487  -14.467 0.33  19.753 ? 413 ALA D HA   1 c 
ATOM   7406 H HB1  . ALA B 1 245 ? 26.132  36.049  -14.297 0.33  19.878 ? 413 ALA D HB1  1 c 
ATOM   7407 H HB2  . ALA B 1 245 ? 27.064  34.786  -14.518 0.33  19.878 ? 413 ALA D HB2  1 c 
ATOM   7408 H HB3  . ALA B 1 245 ? 27.204  35.653  -13.198 0.33  19.878 ? 413 ALA D HB3  1 c 
ATOM   7409 N N    . ALA B 1 246 ? 29.885  35.031  -15.325 0.33  20.317 ? 414 ALA D N    1 ? 
ATOM   7410 C CA   . ALA B 1 246 ? 31.222  34.475  -15.203 0.33  21.015 ? 414 ALA D CA   1 ? 
ATOM   7411 C C    . ALA B 1 246 ? 32.27   35.554  -15.47  0.33  20.55  ? 414 ALA D C    1 ? 
ATOM   7412 O O    . ALA B 1 246 ? 33.27   35.629  -14.756 0.33  20.14  ? 414 ALA D O    1 ? 
ATOM   7413 C CB   . ALA B 1 246 ? 31.396  33.281  -16.117 0.33  22.089 ? 414 ALA D CB   1 ? 
ATOM   7414 H H    . ALA B 1 246 ? 29.318  34.674  -15.947 0.33  20.158 ? 414 ALA D H    1 c 
ATOM   7415 H HA   . ALA B 1 246 ? 31.337  34.17   -14.261 0.33  20.983 ? 414 ALA D HA   1 c 
ATOM   7416 H HB1  . ALA B 1 246 ? 30.75   32.593  -15.883 0.33  21.766 ? 414 ALA D HB1  1 c 
ATOM   7417 H HB2  . ALA B 1 246 ? 31.256  33.552  -17.04  0.33  21.766 ? 414 ALA D HB2  1 c 
ATOM   7418 H HB3  . ALA B 1 246 ? 32.294  32.923  -16.02  0.33  21.766 ? 414 ALA D HB3  1 c 
ATOM   7419 N N    . ARG B 1 247 ? 32.003  36.423  -16.446 0.33  21.217 ? 415 ARG D N    1 ? 
ATOM   7420 C CA   . ARG B 1 247 ? 32.9    37.532  -16.747 0.33  21.725 ? 415 ARG D CA   1 ? 
ATOM   7421 C C    . ARG B 1 247 ? 33.032  38.455  -15.537 0.33  21.002 ? 415 ARG D C    1 ? 
ATOM   7422 O O    . ARG B 1 247 ? 34.142  38.87   -15.19  0.33  22.369 ? 415 ARG D O    1 ? 
ATOM   7423 C CB   . ARG B 1 247 ? 32.399  38.266  -17.996 0.33  22.802 ? 415 ARG D CB   1 ? 
ATOM   7424 C CG   . ARG B 1 247 ? 32.603  37.477  -19.282 0.33  23.948 ? 415 ARG D CG   1 ? 
ATOM   7425 C CD   . ARG B 1 247 ? 31.89   38.113  -20.464 0.33  26.33  ? 415 ARG D CD   1 ? 
ATOM   7426 N NE   . ARG B 1 247 ? 32.511  39.374  -20.883 0.33  27.329 ? 415 ARG D NE   1 ? 
ATOM   7427 C CZ   . ARG B 1 247 ? 31.981  40.251  -21.726 0.33  28.524 ? 415 ARG D CZ   1 ? 
ATOM   7428 N NH1  . ARG B 1 247 ? 30.74   40.112  -22.157 0.33  29.256 ? 415 ARG D NH1  1 ? 
ATOM   7429 N NH2  . ARG B 1 247 ? 32.685  41.299  -22.099 0.33  29.959 ? 415 ARG D NH2  1 ? 
ATOM   7430 H H    . ARG B 1 247 ? 31.241  36.325  -16.94  0.33  21.168 ? 415 ARG D H    1 c 
ATOM   7431 H HA   . ARG B 1 247 ? 33.795  37.155  -16.948 0.33  21.681 ? 415 ARG D HA   1 c 
ATOM   7432 H HB2  . ARG B 1 247 ? 31.442  38.458  -17.89  0.33  22.808 ? 415 ARG D HB2  1 c 
ATOM   7433 H HB3  . ARG B 1 247 ? 32.87   39.123  -18.072 0.33  22.808 ? 415 ARG D HB3  1 c 
ATOM   7434 H HG2  . ARG B 1 247 ? 33.564  37.422  -19.479 0.33  24.201 ? 415 ARG D HG2  1 c 
ATOM   7435 H HG3  . ARG B 1 247 ? 32.265  36.563  -19.158 0.33  24.201 ? 415 ARG D HG3  1 c 
ATOM   7436 H HD2  . ARG B 1 247 ? 31.897  37.486  -21.216 0.33  26     ? 415 ARG D HD2  1 c 
ATOM   7437 H HD3  . ARG B 1 247 ? 30.956  38.28   -20.221 0.33  26     ? 415 ARG D HD3  1 c 
ATOM   7438 H HE   . ARG B 1 247 ? 33.293  39.568  -20.553 0.33  27.37  ? 415 ARG D HE   1 c 
ATOM   7439 H HH11 . ARG B 1 247 ? 30.252  39.43   -21.877 0.33  29.029 ? 415 ARG D HH11 1 c 
ATOM   7440 H HH12 . ARG B 1 247 ? 30.404  40.702  -22.723 0.33  29.029 ? 415 ARG D HH12 1 c 
ATOM   7441 H HH21 . ARG B 1 247 ? 33.501  41.415  -21.78  0.33  29.51  ? 415 ARG D HH21 1 c 
ATOM   7442 H HH22 . ARG B 1 247 ? 32.338  41.881  -22.667 0.33  29.51  ? 415 ARG D HH22 1 c 
ATOM   7443 N N    . VAL B 1 248 ? 31.908  38.747  -14.871 0.33  19.602 ? 416 VAL D N    1 ? 
ATOM   7444 C CA   . VAL B 1 248 ? 31.911  39.65   -13.735 0.33  19.098 ? 416 VAL D CA   1 ? 
ATOM   7445 C C    . VAL B 1 248 ? 32.649  39.002  -12.57  0.33  19.878 ? 416 VAL D C    1 ? 
ATOM   7446 O O    . VAL B 1 248 ? 33.445  39.655  -11.91  0.33  22.154 ? 416 VAL D O    1 ? 
ATOM   7447 C CB   . VAL B 1 248 ? 30.475  40.062  -13.361 0.33  18.448 ? 416 VAL D CB   1 ? 
ATOM   7448 C CG1  . VAL B 1 248 ? 30.41   40.841  -12.051 0.33  17.419 ? 416 VAL D CG1  1 ? 
ATOM   7449 C CG2  . VAL B 1 248 ? 29.823  40.853  -14.484 0.33  18.675 ? 416 VAL D CG2  1 ? 
ATOM   7450 H H    . VAL B 1 248 ? 31.118  38.37   -15.135 0.33  19.811 ? 416 VAL D H    1 c 
ATOM   7451 H HA   . VAL B 1 248 ? 32.4    40.456  -13.993 0.33  19.216 ? 416 VAL D HA   1 c 
ATOM   7452 H HB   . VAL B 1 248 ? 29.958  39.232  -13.241 0.33  18.411 ? 416 VAL D HB   1 c 
ATOM   7453 H HG11 . VAL B 1 248 ? 30.939  41.652  -12.128 0.33  17.716 ? 416 VAL D HG11 1 c 
ATOM   7454 H HG12 . VAL B 1 248 ? 30.762  40.293  -11.329 0.33  17.716 ? 416 VAL D HG12 1 c 
ATOM   7455 H HG13 . VAL B 1 248 ? 29.486  41.075  -11.857 0.33  17.716 ? 416 VAL D HG13 1 c 
ATOM   7456 H HG21 . VAL B 1 248 ? 28.92   41.101  -14.225 0.33  18.608 ? 416 VAL D HG21 1 c 
ATOM   7457 H HG22 . VAL B 1 248 ? 29.79   40.307  -15.288 0.33  18.608 ? 416 VAL D HG22 1 c 
ATOM   7458 H HG23 . VAL B 1 248 ? 30.342  41.656  -14.66  0.33  18.608 ? 416 VAL D HG23 1 c 
ATOM   7459 N N    . ARG B 1 249 ? 32.417  37.703  -12.337 0.33  21.345 ? 417 ARG D N    1 ? 
ATOM   7460 C CA   . ARG B 1 249 ? 33.1    36.976  -11.273 0.33  20.991 ? 417 ARG D CA   1 ? 
ATOM   7461 C C    . ARG B 1 249 ? 34.612  36.943  -11.526 0.33  22.618 ? 417 ARG D C    1 ? 
ATOM   7462 O O    . ARG B 1 249 ? 35.403  37.09   -10.592 0.33  21.288 ? 417 ARG D O    1 ? 
ATOM   7463 C CB   . ARG B 1 249 ? 32.519  35.566  -11.112 0.33  20.42  ? 417 ARG D CB   1 ? 
ATOM   7464 C CG   . ARG B 1 249 ? 33.21   34.691  -10.077 0.33  21.206 ? 417 ARG D CG   1 ? 
ATOM   7465 C CD   . ARG B 1 249 ? 33.166  35.255  -8.681  0.33  23.001 ? 417 ARG D CD   1 ? 
ATOM   7466 N NE   . ARG B 1 249 ? 33.977  34.453  -7.756  0.33  23.741 ? 417 ARG D NE   1 ? 
ATOM   7467 C CZ   . ARG B 1 249 ? 35.292  34.544  -7.571  0.33  23.59  ? 417 ARG D CZ   1 ? 
ATOM   7468 N NH1  . ARG B 1 249 ? 35.977  35.526  -8.136  0.33  22.749 ? 417 ARG D NH1  1 ? 
ATOM   7469 N NH2  . ARG B 1 249 ? 35.905  33.676  -6.789  0.33  22.996 ? 417 ARG D NH2  1 ? 
ATOM   7470 H H    . ARG B 1 249 ? 31.815  37.256  -12.859 0.33  20.907 ? 417 ARG D H    1 c 
ATOM   7471 H HA   . ARG B 1 249 ? 32.943  37.464  -10.425 0.33  21.241 ? 417 ARG D HA   1 c 
ATOM   7472 H HB2  . ARG B 1 249 ? 31.573  35.647  -10.869 0.33  20.727 ? 417 ARG D HB2  1 c 
ATOM   7473 H HB3  . ARG B 1 249 ? 32.563  35.113  -11.981 0.33  20.727 ? 417 ARG D HB3  1 c 
ATOM   7474 H HG2  . ARG B 1 249 ? 32.785  33.805  -10.073 0.33  21.423 ? 417 ARG D HG2  1 c 
ATOM   7475 H HG3  . ARG B 1 249 ? 34.148  34.567  -10.338 0.33  21.423 ? 417 ARG D HG3  1 c 
ATOM   7476 H HD2  . ARG B 1 249 ? 33.502  36.174  -8.692  0.33  22.748 ? 417 ARG D HD2  1 c 
ATOM   7477 H HD3  . ARG B 1 249 ? 32.239  35.273  -8.367  0.33  22.748 ? 417 ARG D HD3  1 c 
ATOM   7478 H HE   . ARG B 1 249 ? 33.56   33.856  -7.278  0.33  23.532 ? 417 ARG D HE   1 c 
ATOM   7479 H HH11 . ARG B 1 249 ? 35.56   36.114  -8.648  0.33  23.005 ? 417 ARG D HH11 1 c 
ATOM   7480 H HH12 . ARG B 1 249 ? 36.848  35.589  -7.998  0.33  23.005 ? 417 ARG D HH12 1 c 
ATOM   7481 H HH21 . ARG B 1 249 ? 35.441  33.032  -6.4    0.33  23.177 ? 417 ARG D HH21 1 c 
ATOM   7482 H HH22 . ARG B 1 249 ? 36.776  33.742  -6.658  0.33  23.177 ? 417 ARG D HH22 1 c 
ATOM   7483 N N    . ALA B 1 250 ? 35.02   36.776  -12.791 0.33  23.461 ? 418 ALA D N    1 ? 
ATOM   7484 C CA   . ALA B 1 250 ? 36.435  36.683  -13.13  0.33  24.642 ? 418 ALA D CA   1 ? 
ATOM   7485 C C    . ALA B 1 250 ? 37.146  38      -12.829 0.33  25.204 ? 418 ALA D C    1 ? 
ATOM   7486 O O    . ALA B 1 250 ? 38.367  38.017  -12.7   0.33  27.054 ? 418 ALA D O    1 ? 
ATOM   7487 C CB   . ALA B 1 250 ? 36.612  36.28   -14.581 0.33  22.698 ? 418 ALA D CB   1 ? 
ATOM   7488 H H    . ALA B 1 250 ? 34.4    36.718  -13.46  0.33  23.515 ? 418 ALA D H    1 c 
ATOM   7489 H HA   . ALA B 1 250 ? 36.841  35.979  -12.552 0.33  24.143 ? 418 ALA D HA   1 c 
ATOM   7490 H HB1  . ALA B 1 250 ? 36.199  35.413  -14.732 0.33  23.257 ? 418 ALA D HB1  1 c 
ATOM   7491 H HB2  . ALA B 1 250 ? 36.192  36.941  -15.157 0.33  23.257 ? 418 ALA D HB2  1 c 
ATOM   7492 H HB3  . ALA B 1 250 ? 37.559  36.226  -14.792 0.33  23.257 ? 418 ALA D HB3  1 c 
ATOM   7493 N N    . ALA B 1 251 ? 36.374  39.088  -12.717 0.33  25.567 ? 419 ALA D N    1 ? 
ATOM   7494 C CA   . ALA B 1 251 ? 36.915  40.41   -12.45  0.33  26.061 ? 419 ALA D CA   1 ? 
ATOM   7495 C C    . ALA B 1 251 ? 36.859  40.731  -10.958 0.33  26.39  ? 419 ALA D C    1 ? 
ATOM   7496 O O    . ALA B 1 251 ? 37.036  41.882  -10.557 0.33  28.214 ? 419 ALA D O    1 ? 
ATOM   7497 C CB   . ALA B 1 251 ? 36.142  41.419  -13.255 0.33  26.762 ? 419 ALA D CB   1 ? 
ATOM   7498 H H    . ALA B 1 251 ? 35.47   38.997  -12.811 0.33  25.591 ? 419 ALA D H    1 c 
ATOM   7499 H HA   . ALA B 1 251 ? 37.869  40.423  -12.738 0.33  26.151 ? 419 ALA D HA   1 c 
ATOM   7500 H HB1  . ALA B 1 251 ? 36.222  41.213  -14.202 0.33  26.551 ? 419 ALA D HB1  1 c 
ATOM   7501 H HB2  . ALA B 1 251 ? 35.204  41.393  -12.999 0.33  26.551 ? 419 ALA D HB2  1 c 
ATOM   7502 H HB3  . ALA B 1 251 ? 36.495  42.31   -13.089 0.33  26.551 ? 419 ALA D HB3  1 c 
ATOM   7503 N N    . GLY B 1 252 ? 36.586  39.71   -10.141 0.33  23.805 ? 420 GLY D N    1 ? 
ATOM   7504 C CA   . GLY B 1 252 ? 36.761  39.793  -8.701  0.33  23.493 ? 420 GLY D CA   1 ? 
ATOM   7505 C C    . GLY B 1 252 ? 35.553  40.383  -7.971  0.33  22.813 ? 420 GLY D C    1 ? 
ATOM   7506 O O    . GLY B 1 252 ? 35.683  40.805  -6.825  0.33  24.197 ? 420 GLY D O    1 ? 
ATOM   7507 H H    . GLY B 1 252 ? 36.276  38.928  -10.499 0.33  24.324 ? 420 GLY D H    1 c 
ATOM   7508 H HA2  . GLY B 1 252 ? 36.94   38.889  -8.352  0.33  23.414 ? 420 GLY D HA2  1 c 
ATOM   7509 H HA3  . GLY B 1 252 ? 37.555  40.347  -8.512  0.33  23.414 ? 420 GLY D HA3  1 c 
ATOM   7510 N N    . LYS B 1 253 ? 34.381  40.383  -8.615  0.33  20.638 ? 421 LYS D N    1 ? 
ATOM   7511 C CA   . LYS B 1 253 ? 33.161  40.845  -7.97   0.33  18.94  ? 421 LYS D CA   1 ? 
ATOM   7512 C C    . LYS B 1 253 ? 32.469  39.677  -7.274  0.33  17.383 ? 421 LYS D C    1 ? 
ATOM   7513 O O    . LYS B 1 253 ? 32.594  38.535  -7.691  0.33  16.948 ? 421 LYS D O    1 ? 
ATOM   7514 C CB   . LYS B 1 253 ? 32.222  41.518  -8.973  0.33  18.08  ? 421 LYS D CB   1 ? 
ATOM   7515 C CG   . LYS B 1 253 ? 32.924  42.542  -9.864  0.33  17.977 ? 421 LYS D CG   1 ? 
ATOM   7516 C CD   . LYS B 1 253 ? 33.616  43.641  -9.066  0.33  17.866 ? 421 LYS D CD   1 ? 
ATOM   7517 C CE   . LYS B 1 253 ? 34.368  44.634  -9.902  0.33  17.215 ? 421 LYS D CE   1 ? 
ATOM   7518 N NZ   . LYS B 1 253 ? 34.917  45.707  -9.073  0.33  17.395 ? 421 LYS D NZ   1 ? 
ATOM   7519 H H    . LYS B 1 253 ? 34.34   40.087  -9.479  0.33  20.733 ? 421 LYS D H    1 c 
ATOM   7520 H HA   . LYS B 1 253 ? 33.412  41.513  -7.282  0.33  18.8   ? 421 LYS D HA   1 c 
ATOM   7521 H HB2  . LYS B 1 253 ? 31.817  40.83   -9.544  0.33  18.248 ? 421 LYS D HB2  1 c 
ATOM   7522 H HB3  . LYS B 1 253 ? 31.5    41.968  -8.485  0.33  18.248 ? 421 LYS D HB3  1 c 
ATOM   7523 H HG2  . LYS B 1 253 ? 33.589  42.076  -10.416 0.33  17.975 ? 421 LYS D HG2  1 c 
ATOM   7524 H HG3  . LYS B 1 253 ? 32.26   42.947  -10.463 0.33  17.975 ? 421 LYS D HG3  1 c 
ATOM   7525 H HD2  . LYS B 1 253 ? 32.94   44.12   -8.539  0.33  17.738 ? 421 LYS D HD2  1 c 
ATOM   7526 H HD3  . LYS B 1 253 ? 34.241  43.224  -8.434  0.33  17.738 ? 421 LYS D HD3  1 c 
ATOM   7527 H HE2  . LYS B 1 253 ? 35.097  44.186  -10.368 0.33  17.404 ? 421 LYS D HE2  1 c 
ATOM   7528 H HE3  . LYS B 1 253 ? 33.771  45.02   -10.568 0.33  17.404 ? 421 LYS D HE3  1 c 
ATOM   7529 H HZ1  . LYS B 1 253 ? 35.478  45.357  -8.453  0.33  17.339 ? 421 LYS D HZ1  1 c 
ATOM   7530 H HZ2  . LYS B 1 253 ? 34.244  46.145  -8.653  0.33  17.339 ? 421 LYS D HZ2  1 c 
ATOM   7531 H HZ3  . LYS B 1 253 ? 35.375  46.291  -9.592  0.33  17.339 ? 421 LYS D HZ3  1 c 
ATOM   7532 N N    . LEU B 1 254 ? 31.744  39.983  -6.202  0.33  17.36  ? 422 LEU D N    1 ? 
ATOM   7533 C CA   . LEU B 1 254 ? 30.912  38.992  -5.538  0.33  16.528 ? 422 LEU D CA   1 ? 
ATOM   7534 C C    . LEU B 1 254 ? 29.67   38.747  -6.383  0.33  16.189 ? 422 LEU D C    1 ? 
ATOM   7535 O O    . LEU B 1 254 ? 28.934  39.689  -6.632  0.33  17.365 ? 422 LEU D O    1 ? 
ATOM   7536 C CB   . LEU B 1 254 ? 30.515  39.54   -4.175  0.33  15.634 ? 422 LEU D CB   1 ? 
ATOM   7537 C CG   . LEU B 1 254 ? 29.54   38.683  -3.369  0.33  14.713 ? 422 LEU D CG   1 ? 
ATOM   7538 C CD1  . LEU B 1 254 ? 30.172  37.334  -3.15   0.33  14.832 ? 422 LEU D CD1  1 ? 
ATOM   7539 C CD2  . LEU B 1 254 ? 29.223  39.372  -2.064  0.33  14.377 ? 422 LEU D CD2  1 ? 
ATOM   7540 H H    . LEU B 1 254 ? 31.767  40.835  -5.871  0.33  17.175 ? 422 LEU D H    1 c 
ATOM   7541 H HA   . LEU B 1 254 ? 31.423  38.15   -5.433  0.33  16.457 ? 422 LEU D HA   1 c 
ATOM   7542 H HB2  . LEU B 1 254 ? 31.334  39.661  -3.642  0.33  15.617 ? 422 LEU D HB2  1 c 
ATOM   7543 H HB3  . LEU B 1 254 ? 30.111  40.428  -4.306  0.33  15.617 ? 422 LEU D HB3  1 c 
ATOM   7544 H HG   . LEU B 1 254 ? 28.704  38.57   -3.89   0.33  14.836 ? 422 LEU D HG   1 c 
ATOM   7545 H HD11 . LEU B 1 254 ? 30.348  36.915  -4.009  0.33  14.796 ? 422 LEU D HD11 1 c 
ATOM   7546 H HD12 . LEU B 1 254 ? 29.569  36.773  -2.634  0.33  14.796 ? 422 LEU D HD12 1 c 
ATOM   7547 H HD13 . LEU B 1 254 ? 31.008  37.442  -2.665  0.33  14.796 ? 422 LEU D HD13 1 c 
ATOM   7548 H HD21 . LEU B 1 254 ? 28.82   40.238  -2.243  0.33  14.476 ? 422 LEU D HD21 1 c 
ATOM   7549 H HD22 . LEU B 1 254 ? 30.041  39.495  -1.554  0.33  14.476 ? 422 LEU D HD22 1 c 
ATOM   7550 H HD23 . LEU B 1 254 ? 28.602  38.827  -1.552  0.33  14.476 ? 422 LEU D HD23 1 c 
ATOM   7551 N N    . VAL B 1 255 ? 29.4    37.499  -6.762  0.33  15.4   ? 423 VAL D N    1 ? 
ATOM   7552 C CA   . VAL B 1 255 ? 28.217  37.207  -7.555  0.33  14.257 ? 423 VAL D CA   1 ? 
ATOM   7553 C C    . VAL B 1 255 ? 27.244  36.396  -6.714  0.33  14.247 ? 423 VAL D C    1 ? 
ATOM   7554 O O    . VAL B 1 255 ? 27.588  35.308  -6.27   0.33  13.764 ? 423 VAL D O    1 ? 
ATOM   7555 C CB   . VAL B 1 255 ? 28.509  36.489  -8.883  0.33  14.452 ? 423 VAL D CB   1 ? 
ATOM   7556 C CG1  . VAL B 1 255 ? 27.215  36.098  -9.591  0.33  13.843 ? 423 VAL D CG1  1 ? 
ATOM   7557 C CG2  . VAL B 1 255 ? 29.352  37.369  -9.796  0.33  14.506 ? 423 VAL D CG2  1 ? 
ATOM   7558 H H    . VAL B 1 255 ? 29.96   36.817  -6.525  0.33  15.317 ? 423 VAL D H    1 c 
ATOM   7559 H HA   . VAL B 1 255 ? 27.788  38.059  -7.767  0.33  14.506 ? 423 VAL D HA   1 c 
ATOM   7560 H HB   . VAL B 1 255 ? 29.017  35.67   -8.674  0.33  14.311 ? 423 VAL D HB   1 c 
ATOM   7561 H HG11 . VAL B 1 255 ? 26.692  36.896  -9.775  0.33  14.02  ? 423 VAL D HG11 1 c 
ATOM   7562 H HG12 . VAL B 1 255 ? 26.702  35.5    -9.022  0.33  14.02  ? 423 VAL D HG12 1 c 
ATOM   7563 H HG13 . VAL B 1 255 ? 27.425  35.649  -10.427 0.33  14.02  ? 423 VAL D HG13 1 c 
ATOM   7564 H HG21 . VAL B 1 255 ? 29.531  36.898  -10.627 0.33  14.49  ? 423 VAL D HG21 1 c 
ATOM   7565 H HG22 . VAL B 1 255 ? 30.192  37.582  -9.356  0.33  14.49  ? 423 VAL D HG22 1 c 
ATOM   7566 H HG23 . VAL B 1 255 ? 28.871  38.192  -9.988  0.33  14.49  ? 423 VAL D HG23 1 c 
ATOM   7567 N N    . LEU B 1 256 ? 26.061  36.974  -6.479  0.33  13.738 ? 424 LEU D N    1 ? 
ATOM   7568 C CA   . LEU B 1 256 ? 25.028  36.388  -5.642  0.33  13.899 ? 424 LEU D CA   1 ? 
ATOM   7569 C C    . LEU B 1 256 ? 23.932  35.87   -6.56   0.33  13.569 ? 424 LEU D C    1 ? 
ATOM   7570 O O    . LEU B 1 256 ? 23.256  36.677  -7.189  0.33  14.775 ? 424 LEU D O    1 ? 
ATOM   7571 C CB   . LEU B 1 256 ? 24.448  37.452  -4.714  0.33  14.922 ? 424 LEU D CB   1 ? 
ATOM   7572 C CG   . LEU B 1 256 ? 25.419  38.192  -3.791  0.33  14.555 ? 424 LEU D CG   1 ? 
ATOM   7573 C CD1  . LEU B 1 256 ? 24.69   39.306  -3.057  0.33  15.128 ? 424 LEU D CD1  1 ? 
ATOM   7574 C CD2  . LEU B 1 256 ? 26.04   37.19   -2.829  0.33  15.224 ? 424 LEU D CD2  1 ? 
ATOM   7575 H H    . LEU B 1 256 ? 25.891  37.784  -6.867  0.33  13.894 ? 424 LEU D H    1 c 
ATOM   7576 H HA   . LEU B 1 256 ? 25.413  35.644  -5.113  0.33  13.986 ? 424 LEU D HA   1 c 
ATOM   7577 H HB2  . LEU B 1 256 ? 23.986  38.12   -5.271  0.33  14.599 ? 424 LEU D HB2  1 c 
ATOM   7578 H HB3  . LEU B 1 256 ? 23.759  37.024  -4.155  0.33  14.599 ? 424 LEU D HB3  1 c 
ATOM   7579 H HG   . LEU B 1 256 ? 26.139  38.591  -4.344  0.33  14.85  ? 424 LEU D HG   1 c 
ATOM   7580 H HD11 . LEU B 1 256 ? 24.312  39.927  -3.702  0.33  14.956 ? 424 LEU D HD11 1 c 
ATOM   7581 H HD12 . LEU B 1 256 ? 25.314  39.778  -2.481  0.33  14.956 ? 424 LEU D HD12 1 c 
ATOM   7582 H HD13 . LEU B 1 256 ? 23.976  38.927  -2.517  0.33  14.956 ? 424 LEU D HD13 1 c 
ATOM   7583 H HD21 . LEU B 1 256 ? 26.533  36.52   -3.331  0.33  15.023 ? 424 LEU D HD21 1 c 
ATOM   7584 H HD22 . LEU B 1 256 ? 25.339  36.756  -2.314  0.33  15.023 ? 424 LEU D HD22 1 c 
ATOM   7585 H HD23 . LEU B 1 256 ? 26.646  37.652  -2.225  0.33  15.023 ? 424 LEU D HD23 1 c 
ATOM   7586 N N    . SER B 1 257 ? 23.769  34.55   -6.665  0.33  12.995 ? 425 SER D N    1 ? 
ATOM   7587 C CA   . SER B 1 257 ? 22.76   34.03   -7.572  0.33  11.793 ? 425 SER D CA   1 ? 
ATOM   7588 C C    . SER B 1 257 ? 21.519  33.678  -6.759  0.33  11.555 ? 425 SER D C    1 ? 
ATOM   7589 O O    . SER B 1 257 ? 21.608  33.087  -5.691  0.33  11.036 ? 425 SER D O    1 ? 
ATOM   7590 C CB   . SER B 1 257 ? 23.256  32.863  -8.406  0.33  11.199 ? 425 SER D CB   1 ? 
ATOM   7591 O OG   . SER B 1 257 ? 23.528  31.722  -7.599  0.33  10.832 ? 425 SER D OG   1 ? 
ATOM   7592 H H    . SER B 1 257 ? 24.282  33.973  -6.176  0.33  12.847 ? 425 SER D H    1 c 
ATOM   7593 H HA   . SER B 1 257 ? 22.513  34.762  -8.193  0.33  11.859 ? 425 SER D HA   1 c 
ATOM   7594 H HB2  . SER B 1 257 ? 22.581  32.634  -9.072  0.33  11.241 ? 425 SER D HB2  1 c 
ATOM   7595 H HB3  . SER B 1 257 ? 24.069  33.127  -8.877  0.33  11.241 ? 425 SER D HB3  1 c 
ATOM   7596 N N    . THR B 1 258 ? 20.364  34.105  -7.261  0.33  11.496 ? 426 THR D N    1 ? 
ATOM   7597 C CA   . THR B 1 258 ? 19.093  33.747  -6.669  0.33  10.924 ? 426 THR D CA   1 ? 
ATOM   7598 C C    . THR B 1 258 ? 18.307  32.95   -7.707  0.33  11.117 ? 426 THR D C    1 ? 
ATOM   7599 O O    . THR B 1 258 ? 18.017  33.452  -8.789  0.33  10.309 ? 426 THR D O    1 ? 
ATOM   7600 C CB   . THR B 1 258 ? 18.301  34.974  -6.229  0.33  10.849 ? 426 THR D CB   1 ? 
ATOM   7601 O OG1  . THR B 1 258 ? 19.033  35.696  -5.242  0.33  11.795 ? 426 THR D OG1  1 ? 
ATOM   7602 C CG2  . THR B 1 258 ? 16.98   34.562  -5.61   0.33  11.063 ? 426 THR D CG2  1 ? 
ATOM   7603 H H    . THR B 1 258 ? 20.369  34.64   -8.002  0.33  11.378 ? 426 THR D H    1 c 
ATOM   7604 H HA   . THR B 1 258 ? 19.26   33.178  -5.886  0.33  11.055 ? 426 THR D HA   1 c 
ATOM   7605 H HB   . THR B 1 258 ? 18.131  35.558  -7.006  0.33  11.082 ? 426 THR D HB   1 c 
ATOM   7606 H HG21 . THR B 1 258 ? 16.491  35.355  -5.33   0.33  10.999 ? 426 THR D HG21 1 c 
ATOM   7607 H HG22 . THR B 1 258 ? 17.145  33.995  -4.838  0.33  10.999 ? 426 THR D HG22 1 c 
ATOM   7608 H HG23 . THR B 1 258 ? 16.453  34.072  -6.264  0.33  10.999 ? 426 THR D HG23 1 c 
ATOM   7609 N N    . ASP B 1 259 ? 17.94   31.716  -7.34   0.33  10.752 ? 427 ASP D N    1 ? 
ATOM   7610 C CA   . ASP B 1 259 ? 17.061  30.92   -8.173  0.33  11.081 ? 427 ASP D CA   1 ? 
ATOM   7611 C C    . ASP B 1 259 ? 15.801  30.608  -7.384  0.33  11.327 ? 427 ASP D C    1 ? 
ATOM   7612 O O    . ASP B 1 259 ? 15.756  30.798  -6.183  0.33  10.379 ? 427 ASP D O    1 ? 
ATOM   7613 C CB   . ASP B 1 259 ? 17.789  29.734  -8.769  0.33  11.408 ? 427 ASP D CB   1 ? 
ATOM   7614 C CG   . ASP B 1 259 ? 18.795  30.175  -9.815  0.33  11.592 ? 427 ASP D CG   1 ? 
ATOM   7615 O OD1  . ASP B 1 259 ? 19.887  30.585  -9.411  0.33  11.621 ? 427 ASP D OD1  1 ? 
ATOM   7616 O OD2  . ASP B 1 259 ? 18.418  30.171  -10.997 0.33  11.87  ? 427 ASP D OD2  1 ? 
ATOM   7617 H H    . ASP B 1 259 ? 18.246  31.366  -6.553  0.33  10.912 ? 427 ASP D H    1 c 
ATOM   7618 H HA   . ASP B 1 259 ? 16.798  31.478  -8.94   0.33  11.123 ? 427 ASP D HA   1 c 
ATOM   7619 H HB2  . ASP B 1 259 ? 18.261  29.248  -8.061  0.33  11.374 ? 427 ASP D HB2  1 c 
ATOM   7620 H HB3  . ASP B 1 259 ? 17.142  29.128  -9.187  0.33  11.374 ? 427 ASP D HB3  1 c 
ATOM   7621 N N    . TYR B 1 260 ? 14.763  30.205  -8.103  0.33  11.725 ? 428 TYR D N    1 ? 
ATOM   7622 C CA   . TYR B 1 260 ? 13.446  30.091  -7.509  0.33  12.102 ? 428 TYR D CA   1 ? 
ATOM   7623 C C    . TYR B 1 260 ? 12.937  28.692  -7.803  0.33  11.733 ? 428 TYR D C    1 ? 
ATOM   7624 O O    . TYR B 1 260 ? 12.624  28.38   -8.951  0.33  12.942 ? 428 TYR D O    1 ? 
ATOM   7625 C CB   . TYR B 1 260 ? 12.545  31.192  -8.063  0.33  12.569 ? 428 TYR D CB   1 ? 
ATOM   7626 C CG   . TYR B 1 260 ? 13.022  32.6    -7.743  0.33  12.508 ? 428 TYR D CG   1 ? 
ATOM   7627 C CD1  . TYR B 1 260 ? 12.891  33.113  -6.466  0.33  12.247 ? 428 TYR D CD1  1 ? 
ATOM   7628 C CD2  . TYR B 1 260 ? 13.563  33.42   -8.727  0.33  12.039 ? 428 TYR D CD2  1 ? 
ATOM   7629 C CE1  . TYR B 1 260 ? 13.302  34.396  -6.157  0.33  12.015 ? 428 TYR D CE1  1 ? 
ATOM   7630 C CE2  . TYR B 1 260 ? 13.964  34.71   -8.435  0.33  12.51  ? 428 TYR D CE2  1 ? 
ATOM   7631 C CZ   . TYR B 1 260 ? 13.823  35.203  -7.151  0.33  11.97  ? 428 TYR D CZ   1 ? 
ATOM   7632 O OH   . TYR B 1 260 ? 14.227  36.454  -6.786  0.33  11.309 ? 428 TYR D OH   1 ? 
ATOM   7633 H H    . TYR B 1 260 ? 14.873  29.994  -8.986  0.33  11.712 ? 428 TYR D H    1 c 
ATOM   7634 H HA   . TYR B 1 260 ? 13.527  30.205  -6.525  0.33  12.042 ? 428 TYR D HA   1 c 
ATOM   7635 H HB2  . TYR B 1 260 ? 12.491  31.088  -9.04   0.33  12.447 ? 428 TYR D HB2  1 c 
ATOM   7636 H HB3  . TYR B 1 260 ? 11.642  31.07   -7.696  0.33  12.447 ? 428 TYR D HB3  1 c 
ATOM   7637 H HD1  . TYR B 1 260 ? 12.522  32.571  -5.786  0.33  12.249 ? 428 TYR D HD1  1 c 
ATOM   7638 H HD2  . TYR B 1 260 ? 13.647  33.096  -9.609  0.33  12.252 ? 428 TYR D HD2  1 c 
ATOM   7639 H HE1  . TYR B 1 260 ? 13.208  34.727  -5.28   0.33  12.06  ? 428 TYR D HE1  1 c 
ATOM   7640 H HE2  . TYR B 1 260 ? 14.335  35.253  -9.109  0.33  12.266 ? 428 TYR D HE2  1 c 
ATOM   7641 N N    . ALA B 1 261 ? 12.892  27.859  -6.757  0.33  11.56  ? 429 ALA D N    1 ? 
ATOM   7642 C CA   . ALA B 1 261 ? 12.582  26.456  -6.925  0.33  11.763 ? 429 ALA D CA   1 ? 
ATOM   7643 C C    . ALA B 1 261 ? 12.388  25.826  -5.556  0.33  11.522 ? 429 ALA D C    1 ? 
ATOM   7644 O O    . ALA B 1 261 ? 13.046  26.226  -4.607  0.33  10.653 ? 429 ALA D O    1 ? 
ATOM   7645 C CB   . ALA B 1 261 ? 13.716  25.764  -7.668  0.33  12.21  ? 429 ALA D CB   1 ? 
ATOM   7646 H H    . ALA B 1 261 ? 13.059  28.179  -5.917  0.33  11.647 ? 429 ALA D H    1 c 
ATOM   7647 H HA   . ALA B 1 261 ? 11.735  26.372  -7.443  0.33  11.758 ? 429 ALA D HA   1 c 
ATOM   7648 H HB1  . ALA B 1 261 ? 13.836  26.176  -8.54   0.33  12.077 ? 429 ALA D HB1  1 c 
ATOM   7649 H HB2  . ALA B 1 261 ? 14.54   25.846  -7.158  0.33  12.077 ? 429 ALA D HB2  1 c 
ATOM   7650 H HB3  . ALA B 1 261 ? 13.504  24.822  -7.785  0.33  12.077 ? 429 ALA D HB3  1 c 
ATOM   7651 N N    . THR B 1 262 ? 11.546  24.787  -5.49   0.33  12.047 ? 430 THR D N    1 ? 
ATOM   7652 C CA   . THR B 1 262 ? 11.431  23.988  -4.278  0.33  12.255 ? 430 THR D CA   1 ? 
ATOM   7653 C C    . THR B 1 262 ? 11.795  22.525  -4.519  0.33  12.601 ? 430 THR D C    1 ? 
ATOM   7654 O O    . THR B 1 262 ? 12.034  21.802  -3.567  0.33  13.724 ? 430 THR D O    1 ? 
ATOM   7655 C CB   . THR B 1 262 ? 10.021  24.082  -3.704  0.33  12.343 ? 430 THR D CB   1 ? 
ATOM   7656 O OG1  . THR B 1 262 ? 9.168   23.694  -4.772  0.33  12.641 ? 430 THR D OG1  1 ? 
ATOM   7657 C CG2  . THR B 1 262 ? 9.706   25.449  -3.119  0.33  12.76  ? 430 THR D CG2  1 ? 
ATOM   7658 H H    . THR B 1 262 ? 11.032  24.571  -6.215  0.33  11.966 ? 430 THR D H    1 c 
ATOM   7659 H HA   . THR B 1 262 ? 12.055  24.356  -3.616  0.33  12.293 ? 430 THR D HA   1 c 
ATOM   7660 H HB   . THR B 1 262 ? 9.946   23.42   -2.978  0.33  12.523 ? 430 THR D HB   1 c 
ATOM   7661 H HG21 . THR B 1 262 ? 8.8     25.45   -2.767  0.33  12.636 ? 430 THR D HG21 1 c 
ATOM   7662 H HG22 . THR B 1 262 ? 9.784   26.125  -3.813  0.33  12.636 ? 430 THR D HG22 1 c 
ATOM   7663 H HG23 . THR B 1 262 ? 10.332  25.647  -2.403  0.33  12.636 ? 430 THR D HG23 1 c 
ATOM   7664 N N    . GLN B 1 263 ? 11.817  22.068  -5.776  0.33  13.919 ? 431 GLN D N    1 ? 
ATOM   7665 C CA   . GLN B 1 263 ? 12.061  20.657  -6.028  0.33  16.481 ? 431 GLN D CA   1 ? 
ATOM   7666 C C    . GLN B 1 263 ? 13.525  20.336  -5.738  0.33  15.949 ? 431 GLN D C    1 ? 
ATOM   7667 O O    . GLN B 1 263 ? 14.424  21.037  -6.18   0.33  14.62  ? 431 GLN D O    1 ? 
ATOM   7668 C CB   . GLN B 1 263 ? 11.645  20.237  -7.439  0.33  18.769 ? 431 GLN D CB   1 ? 
ATOM   7669 C CG   . GLN B 1 263 ? 11.661  18.723  -7.636  0.33  21.489 ? 431 GLN D CG   1 ? 
ATOM   7670 C CD   . GLN B 1 263 ? 11.845  18.269  -9.068  0.33  23.415 ? 431 GLN D CD   1 ? 
ATOM   7671 O OE1  . GLN B 1 263 ? 11.024  18.547  -9.947  0.33  24.746 ? 431 GLN D OE1  1 ? 
ATOM   7672 N NE2  . GLN B 1 263 ? 12.894  17.495  -9.294  0.33  24.547 ? 431 GLN D NE2  1 ? 
ATOM   7673 H H    . GLN B 1 263 ? 11.68   22.636  -6.479  0.33  14.118 ? 431 GLN D H    1 c 
ATOM   7674 H HA   . GLN B 1 263 ? 11.509  20.138  -5.39   0.33  16.322 ? 431 GLN D HA   1 c 
ATOM   7675 H HB2  . GLN B 1 263 ? 10.742  20.574  -7.618  0.33  18.793 ? 431 GLN D HB2  1 c 
ATOM   7676 H HB3  . GLN B 1 263 ? 12.253  20.651  -8.086  0.33  18.793 ? 431 GLN D HB3  1 c 
ATOM   7677 H HG2  . GLN B 1 263 ? 12.386  18.34   -7.096  0.33  21.257 ? 431 GLN D HG2  1 c 
ATOM   7678 H HG3  . GLN B 1 263 ? 10.818  18.35   -7.301  0.33  21.257 ? 431 GLN D HG3  1 c 
ATOM   7679 H HE21 . GLN B 1 263 ? 13.057  17.199  -10.114 0.33  24.193 ? 431 GLN D HE21 1 c 
ATOM   7680 H HE22 . GLN B 1 263 ? 13.433  17.273  -8.625  0.33  24.193 ? 431 GLN D HE22 1 c 
ATOM   7681 N N    . SER B 1 264 ? 13.761  19.239  -5.018  0.33  15.585 ? 432 SER D N    1 ? 
ATOM   7682 C CA   . SER B 1 264 ? 15.086  18.933  -4.494  0.33  15.871 ? 432 SER D CA   1 ? 
ATOM   7683 C C    . SER B 1 264 ? 16.147  18.83   -5.592  0.33  14.111 ? 432 SER D C    1 ? 
ATOM   7684 O O    . SER B 1 264 ? 17.262  19.297  -5.397  0.33  13.953 ? 432 SER D O    1 ? 
ATOM   7685 C CB   . SER B 1 264 ? 15.045  17.67   -3.659  0.33  17.467 ? 432 SER D CB   1 ? 
ATOM   7686 O OG   . SER B 1 264 ? 13.826  17.636  -2.936  0.33  21.841 ? 432 SER D OG   1 ? 
ATOM   7687 H H    . SER B 1 264 ? 13.075  18.66   -4.847  0.33  15.735 ? 432 SER D H    1 c 
ATOM   7688 H HA   . SER B 1 264 ? 15.347  19.68   -3.897  0.33  15.841 ? 432 SER D HA   1 c 
ATOM   7689 H HB2  . SER B 1 264 ? 15.107  16.888  -4.241  0.33  18.034 ? 432 SER D HB2  1 c 
ATOM   7690 H HB3  . SER B 1 264 ? 15.799  17.661  -3.039  0.33  18.034 ? 432 SER D HB3  1 c 
ATOM   7691 N N    . ALA B 1 265 ? 15.827  18.244  -6.757  0.33  13.153 ? 433 ALA D N    1 ? 
ATOM   7692 C CA   . ALA B 1 265 ? 16.829  18.111  -7.803  0.33  12.855 ? 433 ALA D CA   1 ? 
ATOM   7693 C C    . ALA B 1 265 ? 17.205  19.478  -8.38   0.33  11.933 ? 433 ALA D C    1 ? 
ATOM   7694 O O    . ALA B 1 265 ? 18.355  19.69   -8.763  0.33  12.158 ? 433 ALA D O    1 ? 
ATOM   7695 C CB   . ALA B 1 265 ? 16.365  17.169  -8.898  0.33  13.506 ? 433 ALA D CB   1 ? 
ATOM   7696 H H    . ALA B 1 265 ? 14.981  17.927  -6.899  0.33  13.308 ? 433 ALA D H    1 c 
ATOM   7697 H HA   . ALA B 1 265 ? 17.649  17.726  -7.385  0.33  12.854 ? 433 ALA D HA   1 c 
ATOM   7698 H HB1  . ALA B 1 265 ? 16.198  16.288  -8.523  0.33  13.31  ? 433 ALA D HB1  1 c 
ATOM   7699 H HB2  . ALA B 1 265 ? 15.546  17.508  -9.297  0.33  13.31  ? 433 ALA D HB2  1 c 
ATOM   7700 H HB3  . ALA B 1 265 ? 17.051  17.1    -9.583  0.33  13.31  ? 433 ALA D HB3  1 c 
ATOM   7701 N N    . HIS B 1 266 ? 16.209  20.367  -8.455  0.33  11.318 ? 434 HIS D N    1 ? 
ATOM   7702 C CA   . HIS B 1 266 ? 16.367  21.729  -8.944  0.33  11.651 ? 434 HIS D CA   1 ? 
ATOM   7703 C C    . HIS B 1 266 ? 17.192  22.566  -7.96   0.33  10.967 ? 434 HIS D C    1 ? 
ATOM   7704 O O    . HIS B 1 266 ? 18.104  23.282  -8.361  0.33  10.147 ? 434 HIS D O    1 ? 
ATOM   7705 C CB   . HIS B 1 266 ? 14.992  22.363  -9.198  0.33  11.783 ? 434 HIS D CB   1 ? 
ATOM   7706 C CG   . HIS B 1 266 ? 14.132  21.613  -10.172 0.33  11.992 ? 434 HIS D CG   1 ? 
ATOM   7707 N ND1  . HIS B 1 266 ? 12.812  21.931  -10.405 0.33  12.651 ? 434 HIS D ND1  1 ? 
ATOM   7708 C CD2  . HIS B 1 266 ? 14.409  20.587  -10.998 0.33  12.083 ? 434 HIS D CD2  1 ? 
ATOM   7709 C CE1  . HIS B 1 266 ? 12.322  21.126  -11.338 0.33  12.23  ? 434 HIS D CE1  1 ? 
ATOM   7710 N NE2  . HIS B 1 266 ? 13.278  20.313  -11.714 0.33  12.222 ? 434 HIS D NE2  1 ? 
ATOM   7711 H H    . HIS B 1 266 ? 15.377  20.104  -8.183  0.33  11.537 ? 434 HIS D H    1 c 
ATOM   7712 H HA   . HIS B 1 266 ? 16.859  21.687  -9.801  0.33  11.481 ? 434 HIS D HA   1 c 
ATOM   7713 H HB2  . HIS B 1 266 ? 14.516  22.43   -8.342  0.33  11.801 ? 434 HIS D HB2  1 c 
ATOM   7714 H HB3  . HIS B 1 266 ? 15.126  23.276  -9.533  0.33  11.801 ? 434 HIS D HB3  1 c 
ATOM   7715 H HD2  . HIS B 1 266 ? 15.232  20.149  -11.089 0.33  12.095 ? 434 HIS D HD2  1 c 
ATOM   7716 H HE1  . HIS B 1 266 ? 11.44   21.133  -11.667 0.33  12.32  ? 434 HIS D HE1  1 c 
ATOM   7717 N N    . VAL B 1 267 ? 16.865  22.484  -6.669  0.33  10.932 ? 435 VAL D N    1 ? 
ATOM   7718 C CA   . VAL B 1 267 ? 17.615  23.191  -5.639  0.33  12.002 ? 435 VAL D CA   1 ? 
ATOM   7719 C C    . VAL B 1 267 ? 19.084  22.787  -5.725  0.33  12.606 ? 435 VAL D C    1 ? 
ATOM   7720 O O    . VAL B 1 267 ? 19.961  23.627  -5.816  0.33  12.786 ? 435 VAL D O    1 ? 
ATOM   7721 C CB   . VAL B 1 267 ? 17.033  22.913  -4.238  0.33  11.523 ? 435 VAL D CB   1 ? 
ATOM   7722 C CG1  . VAL B 1 267 ? 17.887  23.498  -3.112  0.33  11.035 ? 435 VAL D CG1  1 ? 
ATOM   7723 C CG2  . VAL B 1 267 ? 15.612  23.425  -4.125  0.33  11.723 ? 435 VAL D CG2  1 ? 
ATOM   7724 H H    . VAL B 1 267 ? 16.151  21.97   -6.42   0.33  11.173 ? 435 VAL D H    1 c 
ATOM   7725 H HA   . VAL B 1 267 ? 17.547  24.15   -5.817  0.33  11.805 ? 435 VAL D HA   1 c 
ATOM   7726 H HB   . VAL B 1 267 ? 17.011  21.934  -4.122  0.33  11.554 ? 435 VAL D HB   1 c 
ATOM   7727 H HG11 . VAL B 1 267 ? 17.944  24.463  -3.215  0.33  11.176 ? 435 VAL D HG11 1 c 
ATOM   7728 H HG12 . VAL B 1 267 ? 18.779  23.116  -3.148  0.33  11.176 ? 435 VAL D HG12 1 c 
ATOM   7729 H HG13 . VAL B 1 267 ? 17.48   23.289  -2.254  0.33  11.176 ? 435 VAL D HG13 1 c 
ATOM   7730 H HG21 . VAL B 1 267 ? 15.271  23.242  -3.234  0.33  11.663 ? 435 VAL D HG21 1 c 
ATOM   7731 H HG22 . VAL B 1 267 ? 15.053  22.979  -4.783  0.33  11.663 ? 435 VAL D HG22 1 c 
ATOM   7732 H HG23 . VAL B 1 267 ? 15.599  24.383  -4.286  0.33  11.663 ? 435 VAL D HG23 1 c 
ATOM   7733 N N    . ALA B 1 268 ? 19.338  21.48   -5.754  0.33  13.29  ? 436 ALA D N    1 ? 
ATOM   7734 C CA   . ALA B 1 268 ? 20.69   20.952  -5.751  0.33  12.997 ? 436 ALA D CA   1 ? 
ATOM   7735 C C    . ALA B 1 268 ? 21.436  21.436  -6.989  0.33  12.546 ? 436 ALA D C    1 ? 
ATOM   7736 O O    . ALA B 1 268 ? 22.627  21.755  -6.918  0.33  12.776 ? 436 ALA D O    1 ? 
ATOM   7737 C CB   . ALA B 1 268 ? 20.663  19.449  -5.683  0.33  12.666 ? 436 ALA D CB   1 ? 
ATOM   7738 H H    . ALA B 1 268 ? 18.639  20.892  -5.777  0.33  13.058 ? 436 ALA D H    1 c 
ATOM   7739 H HA   . ALA B 1 268 ? 21.16   21.306  -4.946  0.33  12.908 ? 436 ALA D HA   1 c 
ATOM   7740 H HB1  . ALA B 1 268 ? 20.216  19.166  -4.867  0.33  12.764 ? 436 ALA D HB1  1 c 
ATOM   7741 H HB2  . ALA B 1 268 ? 20.184  19.095  -6.451  0.33  12.764 ? 436 ALA D HB2  1 c 
ATOM   7742 H HB3  . ALA B 1 268 ? 21.572  19.105  -5.686  0.33  12.764 ? 436 ALA D HB3  1 c 
ATOM   7743 N N    . ASP B 1 269 ? 20.73   21.464  -8.123  0.33  13.022 ? 437 ASP D N    1 ? 
ATOM   7744 C CA   . ASP B 1 269 ? 21.321  21.865  -9.387  0.33  13.192 ? 437 ASP D CA   1 ? 
ATOM   7745 C C    . ASP B 1 269 ? 21.755  23.33   -9.329  0.33  13.108 ? 437 ASP D C    1 ? 
ATOM   7746 O O    . ASP B 1 269 ? 22.844  23.665  -9.801  0.33  12.712 ? 437 ASP D O    1 ? 
ATOM   7747 C CB   . ASP B 1 269 ? 20.375  21.62   -10.549 0.33  12.973 ? 437 ASP D CB   1 ? 
ATOM   7748 C CG   . ASP B 1 269 ? 20.966  21.93   -11.914 0.33  12.831 ? 437 ASP D CG   1 ? 
ATOM   7749 O OD1  . ASP B 1 269 ? 21.886  21.208  -12.309 0.33  13.014 ? 437 ASP D OD1  1 ? 
ATOM   7750 O OD2  . ASP B 1 269 ? 20.5    22.89   -12.557 0.33  12.287 ? 437 ASP D OD2  1 ? 
ATOM   7751 H H    . ASP B 1 269 ? 19.848  21.226  -8.105  0.33  12.945 ? 437 ASP D H    1 c 
ATOM   7752 H HA   . ASP B 1 269 ? 22.121  21.311  -9.537  0.33  13.102 ? 437 ASP D HA   1 c 
ATOM   7753 H HB2  . ASP B 1 269 ? 20.099  20.68   -10.539 0.33  12.99  ? 437 ASP D HB2  1 c 
ATOM   7754 H HB3  . ASP B 1 269 ? 19.575  22.173  -10.427 0.33  12.99  ? 437 ASP D HB3  1 c 
ATOM   7755 N N    . ALA B 1 270 ? 20.895  24.215  -8.798  0.33  13.079 ? 438 ALA D N    1 ? 
ATOM   7756 C CA   . ALA B 1 270 ? 21.24   25.628  -8.709  0.33  13.218 ? 438 ALA D CA   1 ? 
ATOM   7757 C C    . ALA B 1 270 ? 22.459  25.815  -7.802  0.33  12.554 ? 438 ALA D C    1 ? 
ATOM   7758 O O    . ALA B 1 270 ? 23.434  26.467  -8.177  0.33  12.567 ? 438 ALA D O    1 ? 
ATOM   7759 C CB   . ALA B 1 270 ? 20.059  26.441  -8.232  0.33  13.216 ? 438 ALA D CB   1 ? 
ATOM   7760 H H    . ALA B 1 270 ? 20.083  23.933  -8.488  0.33  13.117 ? 438 ALA D H    1 c 
ATOM   7761 H HA   . ALA B 1 270 ? 21.491  25.937  -9.623  0.33  13.067 ? 438 ALA D HA   1 c 
ATOM   7762 H HB1  . ALA B 1 270 ? 19.318  26.337  -8.853  0.33  13.217 ? 438 ALA D HB1  1 c 
ATOM   7763 H HB2  . ALA B 1 270 ? 19.785  26.135  -7.351  0.33  13.217 ? 438 ALA D HB2  1 c 
ATOM   7764 H HB3  . ALA B 1 270 ? 20.307  27.38   -8.183  0.33  13.217 ? 438 ALA D HB3  1 c 
ATOM   7765 N N    . TYR B 1 271 ? 22.417  25.227  -6.602  0.33  11.769 ? 439 TYR D N    1 ? 
ATOM   7766 C CA   . TYR B 1 271 ? 23.516  25.377  -5.659  0.33  12.16  ? 439 TYR D CA   1 ? 
ATOM   7767 C C    . TYR B 1 271 ? 24.811  24.842  -6.26   0.33  12.612 ? 439 TYR D C    1 ? 
ATOM   7768 O O    . TYR B 1 271 ? 25.849  25.472  -6.127  0.33  12.98  ? 439 TYR D O    1 ? 
ATOM   7769 C CB   . TYR B 1 271 ? 23.221  24.69   -4.325  0.33  11.84  ? 439 TYR D CB   1 ? 
ATOM   7770 C CG   . TYR B 1 271 ? 22.439  25.584  -3.375  0.33  11.552 ? 439 TYR D CG   1 ? 
ATOM   7771 C CD1  . TYR B 1 271 ? 21.05   25.609  -3.383  0.33  11.5   ? 439 TYR D CD1  1 ? 
ATOM   7772 C CD2  . TYR B 1 271 ? 23.094  26.447  -2.502  0.33  11.265 ? 439 TYR D CD2  1 ? 
ATOM   7773 C CE1  . TYR B 1 271 ? 20.336  26.419  -2.517  0.33  11.295 ? 439 TYR D CE1  1 ? 
ATOM   7774 C CE2  . TYR B 1 271 ? 22.392  27.278  -1.641  0.33  11.894 ? 439 TYR D CE2  1 ? 
ATOM   7775 C CZ   . TYR B 1 271 ? 21.007  27.276  -1.66   0.33  11.099 ? 439 TYR D CZ   1 ? 
ATOM   7776 O OH   . TYR B 1 271 ? 20.302  28.109  -0.838  0.33  12.677 ? 439 TYR D OH   1 ? 
ATOM   7777 H H    . TYR B 1 271 ? 21.692  24.724  -6.366  0.33  12.04  ? 439 TYR D H    1 c 
ATOM   7778 H HA   . TYR B 1 271 ? 23.636  26.348  -5.484  0.33  12.105 ? 439 TYR D HA   1 c 
ATOM   7779 H HB2  . TYR B 1 271 ? 22.705  23.872  -4.497  0.33  11.845 ? 439 TYR D HB2  1 c 
ATOM   7780 H HB3  . TYR B 1 271 ? 24.073  24.439  -3.904  0.33  11.845 ? 439 TYR D HB3  1 c 
ATOM   7781 H HD1  . TYR B 1 271 ? 20.581  25.032  -3.965  0.33  11.467 ? 439 TYR D HD1  1 c 
ATOM   7782 H HD2  . TYR B 1 271 ? 24.037  26.459  -2.487  0.33  11.478 ? 439 TYR D HD2  1 c 
ATOM   7783 H HE1  . TYR B 1 271 ? 19.395  26.423  -2.543  0.33  11.312 ? 439 TYR D HE1  1 c 
ATOM   7784 H HE2  . TYR B 1 271 ? 22.855  27.857  -1.059  0.33  11.563 ? 439 TYR D HE2  1 c 
ATOM   7785 N N    . THR B 1 272 ? 24.74   23.693  -6.94   0.33  12.765 ? 440 THR D N    1 ? 
ATOM   7786 C CA   . THR B 1 272 ? 25.924  23.019  -7.442  0.33  13.586 ? 440 THR D CA   1 ? 
ATOM   7787 C C    . THR B 1 272 ? 26.547  23.839  -8.565  0.33  14.375 ? 440 THR D C    1 ? 
ATOM   7788 O O    . THR B 1 272 ? 27.751  24.037  -8.576  0.33  14.732 ? 440 THR D O    1 ? 
ATOM   7789 C CB   . THR B 1 272 ? 25.577  21.605  -7.916  0.33  13.85  ? 440 THR D CB   1 ? 
ATOM   7790 O OG1  . THR B 1 272 ? 25.188  20.944  -6.721  0.33  14.114 ? 440 THR D OG1  1 ? 
ATOM   7791 C CG2  . THR B 1 272 ? 26.755  20.877  -8.537  0.33  13.782 ? 440 THR D CG2  1 ? 
ATOM   7792 H H    . THR B 1 272 ? 23.921  23.317  -7.095  0.33  12.909 ? 440 THR D H    1 c 
ATOM   7793 H HA   . THR B 1 272 ? 26.572  22.95   -6.707  0.33  13.61  ? 440 THR D HA   1 c 
ATOM   7794 H HB   . THR B 1 272 ? 24.819  21.629  -8.547  0.33  13.841 ? 440 THR D HB   1 c 
ATOM   7795 H HG21 . THR B 1 272 ? 26.476  19.989  -8.817  0.33  13.802 ? 440 THR D HG21 1 c 
ATOM   7796 H HG22 . THR B 1 272 ? 27.471  20.8    -7.884  0.33  13.802 ? 440 THR D HG22 1 c 
ATOM   7797 H HG23 . THR B 1 272 ? 27.074  21.374  -9.309  0.33  13.802 ? 440 THR D HG23 1 c 
ATOM   7798 N N    . ARG B 1 273 ? 25.732  24.266  -9.536  0.33  14.806 ? 441 ARG D N    1 ? 
ATOM   7799 C CA   . ARG B 1 273 ? 26.274  24.942  -10.703 0.33  15.802 ? 441 ARG D CA   1 ? 
ATOM   7800 C C    . ARG B 1 273 ? 26.778  26.321  -10.293 0.33  16.231 ? 441 ARG D C    1 ? 
ATOM   7801 O O    . ARG B 1 273 ? 27.825  26.779  -10.762 0.33  16.856 ? 441 ARG D O    1 ? 
ATOM   7802 C CB   . ARG B 1 273 ? 25.218  25.031  -11.799 0.33  16.206 ? 441 ARG D CB   1 ? 
ATOM   7803 C CG   . ARG B 1 273 ? 24.924  23.678  -12.425 0.33  16.661 ? 441 ARG D CG   1 ? 
ATOM   7804 C CD   . ARG B 1 273 ? 23.644  23.711  -13.234 0.33  18.373 ? 441 ARG D CD   1 ? 
ATOM   7805 N NE   . ARG B 1 273 ? 23.726  24.526  -14.447 0.33  19.075 ? 441 ARG D NE   1 ? 
ATOM   7806 C CZ   . ARG B 1 273 ? 22.672  24.773  -15.217 0.33  21.002 ? 441 ARG D CZ   1 ? 
ATOM   7807 N NH1  . ARG B 1 273 ? 21.472  24.316  -14.885 0.33  20.505 ? 441 ARG D NH1  1 ? 
ATOM   7808 N NH2  . ARG B 1 273 ? 22.823  25.527  -16.289 0.33  22.439 ? 441 ARG D NH2  1 ? 
ATOM   7809 H H    . ARG B 1 273 ? 24.83   24.135  -9.47   0.33  14.918 ? 441 ARG D H    1 c 
ATOM   7810 H HA   . ARG B 1 273 ? 27.04   24.412  -11.041 0.33  15.751 ? 441 ARG D HA   1 c 
ATOM   7811 H HB2  . ARG B 1 273 ? 24.391  25.396  -11.419 0.33  16.216 ? 441 ARG D HB2  1 c 
ATOM   7812 H HB3  . ARG B 1 273 ? 25.53   25.647  -12.496 0.33  16.216 ? 441 ARG D HB3  1 c 
ATOM   7813 H HG2  . ARG B 1 273 ? 25.669  23.421  -13.011 0.33  16.931 ? 441 ARG D HG2  1 c 
ATOM   7814 H HG3  . ARG B 1 273 ? 24.841  23.002  -11.717 0.33  16.931 ? 441 ARG D HG3  1 c 
ATOM   7815 H HD2  . ARG B 1 273 ? 23.409  22.794  -13.482 0.33  18.129 ? 441 ARG D HD2  1 c 
ATOM   7816 H HD3  . ARG B 1 273 ? 22.925  24.057  -12.666 0.33  18.129 ? 441 ARG D HD3  1 c 
ATOM   7817 H HE   . ARG B 1 273 ? 24.496  24.863  -14.674 0.33  19.348 ? 441 ARG D HE   1 c 
ATOM   7818 H HH11 . ARG B 1 273 ? 21.372  23.842  -14.146 0.33  20.657 ? 441 ARG D HH11 1 c 
ATOM   7819 H HH12 . ARG B 1 273 ? 20.778  24.487  -15.404 0.33  20.657 ? 441 ARG D HH12 1 c 
ATOM   7820 H HH21 . ARG B 1 273 ? 23.615  25.871  -16.476 0.33  21.987 ? 441 ARG D HH21 1 c 
ATOM   7821 H HH22 . ARG B 1 273 ? 22.13   25.686  -16.815 0.33  21.987 ? 441 ARG D HH22 1 c 
ATOM   7822 N N    . SER B 1 274 ? 26.029  26.966  -9.394  0.33  15.394 ? 442 SER D N    1 ? 
ATOM   7823 C CA   . SER B 1 274 ? 26.399  28.292  -8.921  0.33  16.574 ? 442 SER D CA   1 ? 
ATOM   7824 C C    . SER B 1 274 ? 27.779  28.255  -8.25   0.33  16.523 ? 442 SER D C    1 ? 
ATOM   7825 O O    . SER B 1 274 ? 28.658  29.056  -8.556  0.33  16.189 ? 442 SER D O    1 ? 
ATOM   7826 C CB   . SER B 1 274 ? 25.358  28.854  -8.006  0.33  16.298 ? 442 SER D CB   1 ? 
ATOM   7827 O OG   . SER B 1 274 ? 25.764  30.126  -7.524  0.33  15.791 ? 442 SER D OG   1 ? 
ATOM   7828 H H    . SER B 1 274 ? 25.271  26.572  -9.067  0.33  15.85  ? 442 SER D H    1 c 
ATOM   7829 H HA   . SER B 1 274 ? 26.464  28.886  -9.712  0.33  16.278 ? 442 SER D HA   1 c 
ATOM   7830 H HB2  . SER B 1 274 ? 24.513  28.941  -8.488  0.33  16.238 ? 442 SER D HB2  1 c 
ATOM   7831 H HB3  . SER B 1 274 ? 25.223  28.247  -7.254  0.33  16.238 ? 442 SER D HB3  1 c 
ATOM   7832 N N    . ARG B 1 275 ? 27.978  27.32   -7.32   0.33  16.654 ? 443 ARG D N    1 ? 
ATOM   7833 C CA   . ARG B 1 275 ? 29.24   27.213  -6.603  0.33  16.847 ? 443 ARG D CA   1 ? 
ATOM   7834 C C    . ARG B 1 275 ? 30.366  26.774  -7.54   0.33  17.754 ? 443 ARG D C    1 ? 
ATOM   7835 O O    . ARG B 1 275 ? 31.49   27.239  -7.391  0.33  17.208 ? 443 ARG D O    1 ? 
ATOM   7836 C CB   . ARG B 1 275 ? 29.071  26.273  -5.404  0.33  17.105 ? 443 ARG D CB   1 ? 
ATOM   7837 C CG   . ARG B 1 275 ? 28.33   26.928  -4.249  0.33  17.113 ? 443 ARG D CG   1 ? 
ATOM   7838 C CD   . ARG B 1 275 ? 27.991  25.92   -3.159  0.33  17.735 ? 443 ARG D CD   1 ? 
ATOM   7839 N NE   . ARG B 1 275 ? 27.356  26.618  -2.042  0.33  18.439 ? 443 ARG D NE   1 ? 
ATOM   7840 C CZ   . ARG B 1 275 ? 26.675  26.015  -1.092  0.33  19.021 ? 443 ARG D CZ   1 ? 
ATOM   7841 N NH1  . ARG B 1 275 ? 26.574  24.703  -1.083  0.33  21.123 ? 443 ARG D NH1  1 ? 
ATOM   7842 N NH2  . ARG B 1 275 ? 26.103  26.726  -0.148  0.33  19.653 ? 443 ARG D NH2  1 ? 
ATOM   7843 H H    . ARG B 1 275 ? 27.308  26.73   -7.125  0.33  16.666 ? 443 ARG D H    1 c 
ATOM   7844 H HA   . ARG B 1 275 ? 29.466  28.112  -6.252  0.33  17.019 ? 443 ARG D HA   1 c 
ATOM   7845 H HB2  . ARG B 1 275 ? 28.578  25.474  -5.69   0.33  17.048 ? 443 ARG D HB2  1 c 
ATOM   7846 H HB3  . ARG B 1 275 ? 29.957  25.986  -5.094  0.33  17.048 ? 443 ARG D HB3  1 c 
ATOM   7847 H HG2  . ARG B 1 275 ? 28.887  27.64   -3.866  0.33  17.251 ? 443 ARG D HG2  1 c 
ATOM   7848 H HG3  . ARG B 1 275 ? 27.499  27.332  -4.582  0.33  17.251 ? 443 ARG D HG3  1 c 
ATOM   7849 H HD2  . ARG B 1 275 ? 27.38   25.239  -3.51   0.33  17.757 ? 443 ARG D HD2  1 c 
ATOM   7850 H HD3  . ARG B 1 275 ? 28.806  25.476  -2.848  0.33  17.757 ? 443 ARG D HD3  1 c 
ATOM   7851 H HE   . ARG B 1 275 ? 27.432  27.485  -2.002  0.33  18.409 ? 443 ARG D HE   1 c 
ATOM   7852 H HH11 . ARG B 1 275 ? 26.962  24.229  -1.72   0.33  20.452 ? 443 ARG D HH11 1 c 
ATOM   7853 H HH12 . ARG B 1 275 ? 26.12   24.302  -0.439  0.33  20.452 ? 443 ARG D HH12 1 c 
ATOM   7854 H HH21 . ARG B 1 275 ? 26.17   27.607  -0.16   0.33  19.457 ? 443 ARG D HH21 1 c 
ATOM   7855 H HH22 . ARG B 1 275 ? 25.654  26.319  0.496   0.33  19.457 ? 443 ARG D HH22 1 c 
ATOM   7856 N N    . ALA B 1 276 ? 30.071  25.927  -8.538  0.33  17.454 ? 444 ALA D N    1 ? 
ATOM   7857 C CA   . ALA B 1 276 ? 31.077  25.508  -9.503  0.33  18.184 ? 444 ALA D CA   1 ? 
ATOM   7858 C C    . ALA B 1 276 ? 31.583  26.709  -10.306 0.33  19.183 ? 444 ALA D C    1 ? 
ATOM   7859 O O    . ALA B 1 276 ? 32.759  26.762  -10.663 0.33  19.48  ? 444 ALA D O    1 ? 
ATOM   7860 C CB   . ALA B 1 276 ? 30.53   24.425  -10.408 0.33  18.594 ? 444 ALA D CB   1 ? 
ATOM   7861 H H    . ALA B 1 276 ? 29.22   25.604  -8.617  0.33  17.687 ? 444 ALA D H    1 c 
ATOM   7862 H HA   . ALA B 1 276 ? 31.849  25.136  -8.994  0.33  18.291 ? 444 ALA D HA   1 c 
ATOM   7863 H HB1  . ALA B 1 276 ? 30.269  23.655  -9.876  0.33  18.471 ? 444 ALA D HB1  1 c 
ATOM   7864 H HB2  . ALA B 1 276 ? 29.755  24.761  -10.889 0.33  18.471 ? 444 ALA D HB2  1 c 
ATOM   7865 H HB3  . ALA B 1 276 ? 31.212  24.157  -11.047 0.33  18.471 ? 444 ALA D HB3  1 c 
ATOM   7866 N N    . ALA B 1 277 ? 30.716  27.708  -10.521 0.33  17.911 ? 445 ALA D N    1 ? 
ATOM   7867 C CA   . ALA B 1 277 ? 31.082  28.887  -11.288 0.33  18.333 ? 445 ALA D CA   1 ? 
ATOM   7868 C C    . ALA B 1 277 ? 31.775  29.942  -10.419 0.33  18.475 ? 445 ALA D C    1 ? 
ATOM   7869 O O    . ALA B 1 277 ? 32.186  30.977  -10.932 0.33  21.667 ? 445 ALA D O    1 ? 
ATOM   7870 C CB   . ALA B 1 277 ? 29.851  29.432  -11.962 0.33  18.17  ? 445 ALA D CB   1 ? 
ATOM   7871 H H    . ALA B 1 277 ? 29.871  27.65   -10.178 0.33  18.302 ? 445 ALA D H    1 c 
ATOM   7872 H HA   . ALA B 1 277 ? 31.728  28.602  -11.991 0.33  18.245 ? 445 ALA D HA   1 c 
ATOM   7873 H HB1  . ALA B 1 277 ? 29.476  28.758  -12.554 0.33  18.218 ? 445 ALA D HB1  1 c 
ATOM   7874 H HB2  . ALA B 1 277 ? 29.19   29.673  -11.291 0.33  18.218 ? 445 ALA D HB2  1 c 
ATOM   7875 H HB3  . ALA B 1 277 ? 30.084  30.221  -12.481 0.33  18.218 ? 445 ALA D HB3  1 c 
ATOM   7876 N N    . GLY B 1 278 ? 31.87   29.701  -9.105  0.33  18.401 ? 446 GLY D N    1 ? 
ATOM   7877 C CA   . GLY B 1 278 ? 32.442  30.653  -8.158  0.33  17.656 ? 446 GLY D CA   1 ? 
ATOM   7878 C C    . GLY B 1 278 ? 31.43   31.713  -7.714  0.33  16.541 ? 446 GLY D C    1 ? 
ATOM   7879 O O    . GLY B 1 278 ? 31.799  32.782  -7.229  0.33  16.259 ? 446 GLY D O    1 ? 
ATOM   7880 H H    . GLY B 1 278 ? 31.563  28.902  -8.784  0.33  18.248 ? 446 GLY D H    1 c 
ATOM   7881 H HA2  . GLY B 1 278 ? 32.769  30.162  -7.369  0.33  17.574 ? 446 GLY D HA2  1 c 
ATOM   7882 H HA3  . GLY B 1 278 ? 33.216  31.097  -8.579  0.33  17.574 ? 446 GLY D HA3  1 c 
ATOM   7883 N N    . PHE B 1 279 ? 30.144  31.419  -7.89   0.33  15.138 ? 447 PHE D N    1 ? 
ATOM   7884 C CA   . PHE B 1 279 ? 29.104  32.313  -7.428  0.33  15.241 ? 447 PHE D CA   1 ? 
ATOM   7885 C C    . PHE B 1 279 ? 28.66   31.86   -6.04   0.33  15.603 ? 447 PHE D C    1 ? 
ATOM   7886 O O    . PHE B 1 279 ? 29.01   30.776  -5.576  0.33  16.994 ? 447 PHE D O    1 ? 
ATOM   7887 C CB   . PHE B 1 279 ? 27.891  32.351  -8.363  0.33  15.267 ? 447 PHE D CB   1 ? 
ATOM   7888 C CG   . PHE B 1 279 ? 28.158  32.545  -9.848  0.33  15.615 ? 447 PHE D CG   1 ? 
ATOM   7889 C CD1  . PHE B 1 279 ? 29.321  33.165  -10.293 0.33  15.464 ? 447 PHE D CD1  1 ? 
ATOM   7890 C CD2  . PHE B 1 279 ? 27.244  32.088  -10.794 0.33  15.066 ? 447 PHE D CD2  1 ? 
ATOM   7891 C CE1  . PHE B 1 279 ? 29.514  33.393  -11.645 0.33  15.814 ? 447 PHE D CE1  1 ? 
ATOM   7892 C CE2  . PHE B 1 279 ? 27.471  32.272  -12.15  0.33  15.315 ? 447 PHE D CE2  1 ? 
ATOM   7893 C CZ   . PHE B 1 279 ? 28.602  32.926  -12.571 0.33  15.573 ? 447 PHE D CZ   1 ? 
ATOM   7894 H H    . PHE B 1 279 ? 29.909  30.641  -8.308  0.33  15.485 ? 447 PHE D H    1 c 
ATOM   7895 H HA   . PHE B 1 279 ? 29.483  33.23   -7.36   0.33  15.291 ? 447 PHE D HA   1 c 
ATOM   7896 H HB2  . PHE B 1 279 ? 27.395  31.511  -8.247  0.33  15.34  ? 447 PHE D HB2  1 c 
ATOM   7897 H HB3  . PHE B 1 279 ? 27.299  33.074  -8.059  0.33  15.34  ? 447 PHE D HB3  1 c 
ATOM   7898 H HD1  . PHE B 1 279 ? 29.937  33.508  -9.666  0.33  15.574 ? 447 PHE D HD1  1 c 
ATOM   7899 H HD2  . PHE B 1 279 ? 26.458  31.651  -10.507 0.33  15.256 ? 447 PHE D HD2  1 c 
ATOM   7900 H HE1  . PHE B 1 279 ? 30.305  33.815  -11.939 0.33  15.668 ? 447 PHE D HE1  1 c 
ATOM   7901 H HE2  . PHE B 1 279 ? 26.839  31.965  -12.78  0.33  15.323 ? 447 PHE D HE2  1 c 
ATOM   7902 H HZ   . PHE B 1 279 ? 28.762  33.047  -13.494 0.33  15.563 ? 447 PHE D HZ   1 c 
ATOM   7903 N N    . VAL B 1 280 ? 27.874  32.721  -5.389  0.33  15.17  ? 448 VAL D N    1 ? 
ATOM   7904 C CA   . VAL B 1 280 ? 27.304  32.401  -4.101  0.33  15.102 ? 448 VAL D CA   1 ? 
ATOM   7905 C C    . VAL B 1 280 ? 25.804  32.249  -4.273  0.33  14.469 ? 448 VAL D C    1 ? 
ATOM   7906 O O    . VAL B 1 280 ? 25.12   33.213  -4.585  0.33  14.678 ? 448 VAL D O    1 ? 
ATOM   7907 C CB   . VAL B 1 280 ? 27.651  33.487  -3.078  0.33  15.158 ? 448 VAL D CB   1 ? 
ATOM   7908 C CG1  . VAL B 1 280 ? 26.975  33.192  -1.755  0.33  15.423 ? 448 VAL D CG1  1 ? 
ATOM   7909 C CG2  . VAL B 1 280 ? 29.157  33.618  -2.917  0.33  14.703 ? 448 VAL D CG2  1 ? 
ATOM   7910 H H    . VAL B 1 280 ? 27.691  33.534  -5.764  0.33  15.257 ? 448 VAL D H    1 c 
ATOM   7911 H HA   . VAL B 1 280 ? 27.676  31.55   -3.797  0.33  15.006 ? 448 VAL D HA   1 c 
ATOM   7912 H HB   . VAL B 1 280 ? 27.3    34.341  -3.423  0.33  15.111 ? 448 VAL D HB   1 c 
ATOM   7913 H HG11 . VAL B 1 280 ? 27.273  32.329  -1.422  0.33  15.344 ? 448 VAL D HG11 1 c 
ATOM   7914 H HG12 . VAL B 1 280 ? 26.011  33.175  -1.88   0.33  15.344 ? 448 VAL D HG12 1 c 
ATOM   7915 H HG13 . VAL B 1 280 ? 27.204  33.883  -1.111  0.33  15.344 ? 448 VAL D HG13 1 c 
ATOM   7916 H HG21 . VAL B 1 280 ? 29.355  34.314  -2.268  0.33  14.836 ? 448 VAL D HG21 1 c 
ATOM   7917 H HG22 . VAL B 1 280 ? 29.556  33.85   -3.772  0.33  14.836 ? 448 VAL D HG22 1 c 
ATOM   7918 H HG23 . VAL B 1 280 ? 29.526  32.774  -2.607  0.33  14.836 ? 448 VAL D HG23 1 c 
ATOM   7919 N N    . PRO B 1 281 ? 25.282  31.004  -4.16   0.33  13.637 ? 449 PRO D N    1 ? 
ATOM   7920 C CA   . PRO B 1 281 ? 23.864  30.735  -4.411  0.33  13.415 ? 449 PRO D CA   1 ? 
ATOM   7921 C C    . PRO B 1 281 ? 22.905  30.865  -3.239  0.33  11.726 ? 449 PRO D C    1 ? 
ATOM   7922 O O    . PRO B 1 281 ? 23.27   30.701  -2.068  0.33  11.32  ? 449 PRO D O    1 ? 
ATOM   7923 C CB   . PRO B 1 281 ? 23.886  29.296  -4.915  0.33  13.5   ? 449 PRO D CB   1 ? 
ATOM   7924 C CG   . PRO B 1 281 ? 25.049  28.672  -4.163  0.33  14.509 ? 449 PRO D CG   1 ? 
ATOM   7925 C CD   . PRO B 1 281 ? 26.08   29.779  -4.025  0.33  13.991 ? 449 PRO D CD   1 ? 
ATOM   7926 H HA   . PRO B 1 281 ? 23.564  31.328  -5.144  0.33  13.145 ? 449 PRO D HA   1 c 
ATOM   7927 H HB2  . PRO B 1 281 ? 23.04   28.835  -4.704  0.33  13.701 ? 449 PRO D HB2  1 c 
ATOM   7928 H HB3  . PRO B 1 281 ? 24.037  29.264  -5.889  0.33  13.701 ? 449 PRO D HB3  1 c 
ATOM   7929 H HG2  . PRO B 1 281 ? 24.762  28.356  -3.281  0.33  14.158 ? 449 PRO D HG2  1 c 
ATOM   7930 H HG3  . PRO B 1 281 ? 25.42   27.915  -4.663  0.33  14.158 ? 449 PRO D HG3  1 c 
ATOM   7931 H HD2  . PRO B 1 281 ? 26.524  29.74   -3.149  0.33  14.021 ? 449 PRO D HD2  1 c 
ATOM   7932 H HD3  . PRO B 1 281 ? 26.759  29.718  -4.734  0.33  14.021 ? 449 PRO D HD3  1 c 
ATOM   7933 N N    . TYR B 1 282 ? 21.67   31.168  -3.625  0.33  11.505 ? 450 TYR D N    1 ? 
ATOM   7934 C CA   . TYR B 1 282 ? 20.509  31.063  -2.773  0.33  11.188 ? 450 TYR D CA   1 ? 
ATOM   7935 C C    . TYR B 1 282 ? 19.35   30.606  -3.647  0.33  11.749 ? 450 TYR D C    1 ? 
ATOM   7936 O O    . TYR B 1 282 ? 19.236  31.007  -4.806  0.33  10.579 ? 450 TYR D O    1 ? 
ATOM   7937 C CB   . TYR B 1 282 ? 20.139  32.407  -2.155  0.33  11.142 ? 450 TYR D CB   1 ? 
ATOM   7938 C CG   . TYR B 1 282 ? 19.118  32.361  -1.035  0.33  11.247 ? 450 TYR D CG   1 ? 
ATOM   7939 C CD1  . TYR B 1 282 ? 19.114  31.338  -0.086  0.33  10.821 ? 450 TYR D CD1  1 ? 
ATOM   7940 C CD2  . TYR B 1 282 ? 18.156  33.353  -0.934  0.33  11.332 ? 450 TYR D CD2  1 ? 
ATOM   7941 C CE1  . TYR B 1 282 ? 18.198  31.342  0.95    0.33  11.809 ? 450 TYR D CE1  1 ? 
ATOM   7942 C CE2  . TYR B 1 282 ? 17.235  33.366  0.095   0.33  11.708 ? 450 TYR D CE2  1 ? 
ATOM   7943 C CZ   . TYR B 1 282 ? 17.261  32.364  1.042   0.33  11.65  ? 450 TYR D CZ   1 ? 
ATOM   7944 O OH   . TYR B 1 282 ? 16.332  32.418  2.031   0.33  13.148 ? 450 TYR D OH   1 ? 
ATOM   7945 H H    . TYR B 1 282 ? 21.548  31.461  -4.483  0.33  11.484 ? 450 TYR D H    1 c 
ATOM   7946 H HA   . TYR B 1 282 ? 20.677  30.395  -2.057  0.33  11.341 ? 450 TYR D HA   1 c 
ATOM   7947 H HB2  . TYR B 1 282 ? 20.96   32.823  -1.812  0.33  11.176 ? 450 TYR D HB2  1 c 
ATOM   7948 H HB3  . TYR B 1 282 ? 19.794  32.988  -2.869  0.33  11.176 ? 450 TYR D HB3  1 c 
ATOM   7949 H HD1  . TYR B 1 282 ? 19.766  30.657  -0.13   0.33  11.155 ? 450 TYR D HD1  1 c 
ATOM   7950 H HD2  . TYR B 1 282 ? 18.151  34.056  -1.564  0.33  11.402 ? 450 TYR D HD2  1 c 
ATOM   7951 H HE1  . TYR B 1 282 ? 18.21   30.655  1.595   0.33  11.54  ? 450 TYR D HE1  1 c 
ATOM   7952 H HE2  . TYR B 1 282 ? 16.598  34.058  0.155   0.33  11.61  ? 450 TYR D HE2  1 c 
ATOM   7953 N N    . VAL B 1 283 ? 18.506  29.754  -3.078  0.33  11.39  ? 451 VAL D N    1 ? 
ATOM   7954 C CA   . VAL B 1 283 ? 17.278  29.385  -3.751  0.33  12.396 ? 451 VAL D CA   1 ? 
ATOM   7955 C C    . VAL B 1 283 ? 16.119  29.698  -2.818  0.33  12.469 ? 451 VAL D C    1 ? 
ATOM   7956 O O    . VAL B 1 283 ? 16.161  29.379  -1.626  0.33  13.107 ? 451 VAL D O    1 ? 
ATOM   7957 C CB   . VAL B 1 283 ? 17.278  27.904  -4.16   0.33  12.145 ? 451 VAL D CB   1 ? 
ATOM   7958 C CG1  . VAL B 1 283 ? 15.956  27.525  -4.791  0.33  12.76  ? 451 VAL D CG1  1 ? 
ATOM   7959 C CG2  . VAL B 1 283 ? 18.418  27.589  -5.117  0.33  12.124 ? 451 VAL D CG2  1 ? 
ATOM   7960 H H    . VAL B 1 283 ? 18.696  29.396  -2.258  0.33  11.695 ? 451 VAL D H    1 c 
ATOM   7961 H HA   . VAL B 1 283 ? 17.189  29.932  -4.555  0.33  12.161 ? 451 VAL D HA   1 c 
ATOM   7962 H HB   . VAL B 1 283 ? 17.399  27.369  -3.341  0.33  12.3   ? 451 VAL D HB   1 c 
ATOM   7963 H HG11 . VAL B 1 283 ? 15.804  28.071  -5.581  0.33  12.574 ? 451 VAL D HG11 1 c 
ATOM   7964 H HG12 . VAL B 1 283 ? 15.238  27.672  -4.153  0.33  12.574 ? 451 VAL D HG12 1 c 
ATOM   7965 H HG13 . VAL B 1 283 ? 15.975  26.587  -5.046  0.33  12.574 ? 451 VAL D HG13 1 c 
ATOM   7966 H HG21 . VAL B 1 283 ? 18.387  26.649  -5.362  0.33  12.13  ? 451 VAL D HG21 1 c 
ATOM   7967 H HG22 . VAL B 1 283 ? 19.267  27.783  -4.685  0.33  12.13  ? 451 VAL D HG22 1 c 
ATOM   7968 H HG23 . VAL B 1 283 ? 18.331  28.134  -5.917  0.33  12.13  ? 451 VAL D HG23 1 c 
ATOM   7969 N N    . THR B 1 284 ? 15.095  30.338  -3.361  0.33  12.038 ? 452 THR D N    1 ? 
ATOM   7970 C CA   . THR B 1 284 ? 13.996  30.777  -2.529  0.33  12.311 ? 452 THR D CA   1 ? 
ATOM   7971 C C    . THR B 1 284 ? 12.741  30.861  -3.394  0.33  12.431 ? 452 THR D C    1 ? 
ATOM   7972 O O    . THR B 1 284 ? 12.675  30.204  -4.436  0.33  12.212 ? 452 THR D O    1 ? 
ATOM   7973 C CB   . THR B 1 284 ? 14.412  32.079  -1.831  0.33  11.698 ? 452 THR D CB   1 ? 
ATOM   7974 O OG1  . THR B 1 284 ? 13.369  32.372  -0.908  0.33  12.041 ? 452 THR D OG1  1 ? 
ATOM   7975 C CG2  . THR B 1 284 ? 14.631  33.226  -2.801  0.33  12.029 ? 452 THR D CG2  1 ? 
ATOM   7976 H H    . THR B 1 284 ? 15.076  30.504  -4.259  0.33  12.201 ? 452 THR D H    1 c 
ATOM   7977 H HA   . THR B 1 284 ? 13.848  30.095  -1.838  0.33  12.165 ? 452 THR D HA   1 c 
ATOM   7978 H HB   . THR B 1 284 ? 15.25   31.924  -1.333  0.33  11.935 ? 452 THR D HB   1 c 
ATOM   7979 H HG21 . THR B 1 284 ? 14.901  34.019  -2.31   0.33  11.93  ? 452 THR D HG21 1 c 
ATOM   7980 H HG22 . THR B 1 284 ? 13.805  33.408  -3.28   0.33  11.93  ? 452 THR D HG22 1 c 
ATOM   7981 H HG23 . THR B 1 284 ? 15.326  32.986  -3.436  0.33  11.93  ? 452 THR D HG23 1 c 
ATOM   7982 N N    . VAL B 1 285 ? 11.756  31.627  -2.917  0.33  12.997 ? 453 VAL D N    1 ? 
ATOM   7983 C CA   . VAL B 1 285 ? 10.48   31.805  -3.588  0.33  14.31  ? 453 VAL D CA   1 ? 
ATOM   7984 C C    . VAL B 1 285 ? 10.425  33.209  -4.194  0.33  14.191 ? 453 VAL D C    1 ? 
ATOM   7985 O O    . VAL B 1 285 ? 10.988  34.159  -3.659  0.33  12.202 ? 453 VAL D O    1 ? 
ATOM   7986 C CB   . VAL B 1 285 ? 9.303   31.547  -2.629  0.33  15.64  ? 453 VAL D CB   1 ? 
ATOM   7987 C CG1  . VAL B 1 285 ? 9.202   30.068  -2.27   0.33  17.606 ? 453 VAL D CG1  1 ? 
ATOM   7988 C CG2  . VAL B 1 285 ? 9.385   32.423  -1.386  0.33  14.26  ? 453 VAL D CG2  1 ? 
ATOM   7989 H H    . VAL B 1 285 ? 11.891  32.063  -2.125  0.33  13.144 ? 453 VAL D H    1 c 
ATOM   7990 H HA   . VAL B 1 285 ? 10.428  31.155  -4.316  0.33  14.252 ? 453 VAL D HA   1 c 
ATOM   7991 H HB   . VAL B 1 285 ? 8.479   31.793  -3.112  0.33  15.459 ? 453 VAL D HB   1 c 
ATOM   7992 H HG11 . VAL B 1 285 ? 10.024  29.782  -1.837  0.33  17.003 ? 453 VAL D HG11 1 c 
ATOM   7993 H HG12 . VAL B 1 285 ? 9.064   29.546  -3.078  0.33  17.003 ? 453 VAL D HG12 1 c 
ATOM   7994 H HG13 . VAL B 1 285 ? 8.453   29.931  -1.665  0.33  17.003 ? 453 VAL D HG13 1 c 
ATOM   7995 H HG21 . VAL B 1 285 ? 8.628   32.236  -0.805  0.33  14.653 ? 453 VAL D HG21 1 c 
ATOM   7996 H HG22 . VAL B 1 285 ? 9.368   33.36   -1.646  0.33  14.653 ? 453 VAL D HG22 1 c 
ATOM   7997 H HG23 . VAL B 1 285 ? 10.211  32.236  -0.91   0.33  14.653 ? 453 VAL D HG23 1 c 
ATOM   7998 N N    . ARG B 1 286 ? 9.711   33.354  -5.31   0.33  14.99  ? 454 ARG D N    1 ? 
ATOM   7999 C CA   . ARG B 1 286 ? 9.746   34.604  -6.062  0.33  15.297 ? 454 ARG D CA   1 ? 
ATOM   8000 C C    . ARG B 1 286 ? 9.166   35.769  -5.255  0.33  14.498 ? 454 ARG D C    1 ? 
ATOM   8001 O O    . ARG B 1 286 ? 9.521   36.92   -5.472  0.33  14     ? 454 ARG D O    1 ? 
ATOM   8002 C CB   . ARG B 1 286 ? 9.033   34.507  -7.408  0.33  16.926 ? 454 ARG D CB   1 ? 
ATOM   8003 C CG   . ARG B 1 286 ? 9.473   35.675  -8.283  0.33  17.612 ? 454 ARG D CG   1 ? 
ATOM   8004 C CD   . ARG B 1 286 ? 9.221   35.475  -9.756  0.33  19.083 ? 454 ARG D CD   1 ? 
ATOM   8005 N NE   . ARG B 1 286 ? 9.864   34.25   -10.251 0.33  20.679 ? 454 ARG D NE   1 ? 
ATOM   8006 C CZ   . ARG B 1 286 ? 11.033  34.185  -10.864 0.33  18.847 ? 454 ARG D CZ   1 ? 
ATOM   8007 N NH1  . ARG B 1 286 ? 11.402  33.063  -11.45  0.33  19.25  ? 454 ARG D NH1  1 ? 
ATOM   8008 N NH2  . ARG B 1 286 ? 11.808  35.247  -10.938 0.33  18.267 ? 454 ARG D NH2  1 ? 
ATOM   8009 H H    . ARG B 1 286 ? 9.192   32.665  -5.612  0.33  14.862 ? 454 ARG D H    1 c 
ATOM   8010 H HA   . ARG B 1 286 ? 10.697  34.813  -6.25   0.33  15.373 ? 454 ARG D HA   1 c 
ATOM   8011 H HB2  . ARG B 1 286 ? 9.26    33.66   -7.848  0.33  16.694 ? 454 ARG D HB2  1 c 
ATOM   8012 H HB3  . ARG B 1 286 ? 8.061   34.541  -7.275  0.33  16.694 ? 454 ARG D HB3  1 c 
ATOM   8013 H HG2  . ARG B 1 286 ? 9.001   36.485  -7.991  0.33  17.78  ? 454 ARG D HG2  1 c 
ATOM   8014 H HG3  . ARG B 1 286 ? 10.432  35.829  -8.146  0.33  17.78  ? 454 ARG D HG3  1 c 
ATOM   8015 H HD2  . ARG B 1 286 ? 8.257   35.421  -9.916  0.33  19.096 ? 454 ARG D HD2  1 c 
ATOM   8016 H HD3  . ARG B 1 286 ? 9.568   36.245  -10.251 0.33  19.096 ? 454 ARG D HD3  1 c 
ATOM   8017 H HE   . ARG B 1 286 ? 9.44    33.498  -10.133 0.33  19.858 ? 454 ARG D HE   1 c 
ATOM   8018 H HH11 . ARG B 1 286 ? 10.865  32.361  -11.431 0.33  19.125 ? 454 ARG D HH11 1 c 
ATOM   8019 H HH12 . ARG B 1 286 ? 12.184  33.018  -11.86  0.33  19.125 ? 454 ARG D HH12 1 c 
ATOM   8020 H HH21 . ARG B 1 286 ? 11.546  36.007  -10.572 0.33  18.443 ? 454 ARG D HH21 1 c 
ATOM   8021 H HH22 . ARG B 1 286 ? 12.586  35.194  -11.353 0.33  18.443 ? 454 ARG D HH22 1 c 
ATOM   8022 N N    . ALA B 1 287 ? 8.274   35.462  -4.32   0.33  14.375 ? 455 ALA D N    1 ? 
ATOM   8023 C CA   . ALA B 1 287 ? 7.666   36.452  -3.45   0.33  14.511 ? 455 ALA D CA   1 ? 
ATOM   8024 C C    . ALA B 1 287 ? 8.691   37.103  -2.519  0.33  14.635 ? 455 ALA D C    1 ? 
ATOM   8025 O O    . ALA B 1 287 ? 8.427   38.173  -1.968  0.33  15.317 ? 455 ALA D O    1 ? 
ATOM   8026 C CB   . ALA B 1 287 ? 6.563   35.779  -2.651  0.33  15.62  ? 455 ALA D CB   1 ? 
ATOM   8027 H H    . ALA B 1 287 ? 8.032   34.586  -4.217  0.33  14.435 ? 455 ALA D H    1 c 
ATOM   8028 H HA   . ALA B 1 287 ? 7.266   37.165  -4.022  0.33  14.703 ? 455 ALA D HA   1 c 
ATOM   8029 H HB1  . ALA B 1 287 ? 5.897   35.413  -3.257  0.33  15.284 ? 455 ALA D HB1  1 c 
ATOM   8030 H HB2  . ALA B 1 287 ? 6.939   35.061  -2.116  0.33  15.284 ? 455 ALA D HB2  1 c 
ATOM   8031 H HB3  . ALA B 1 287 ? 6.141   36.43   -2.064  0.33  15.284 ? 455 ALA D HB3  1 c 
ATOM   8032 N N    . LEU B 1 288 ? 9.838   36.445  -2.309  0.33  14.342 ? 456 LEU D N    1 ? 
ATOM   8033 C CA   . LEU B 1 288 ? 10.875  36.948  -1.423  0.33  14.513 ? 456 LEU D CA   1 ? 
ATOM   8034 C C    . LEU B 1 288 ? 10.267  37.385  -0.092  0.33  13.806 ? 456 LEU D C    1 ? 
ATOM   8035 O O    . LEU B 1 288 ? 10.566  38.467  0.398   0.33  13.408 ? 456 LEU D O    1 ? 
ATOM   8036 C CB   . LEU B 1 288 ? 11.61   38.087  -2.126  0.33  15.371 ? 456 LEU D CB   1 ? 
ATOM   8037 C CG   . LEU B 1 288 ? 12.405  37.699  -3.377  0.33  16.257 ? 456 LEU D CG   1 ? 
ATOM   8038 C CD1  . LEU B 1 288 ? 12.994  38.925  -4.064  0.33  16.537 ? 456 LEU D CD1  1 ? 
ATOM   8039 C CD2  . LEU B 1 288 ? 13.499  36.715  -3.063  0.33  16.347 ? 456 LEU D CD2  1 ? 
ATOM   8040 H H    . LEU B 1 288 ? 9.976   35.649  -2.736  0.33  14.45  ? 456 LEU D H    1 c 
ATOM   8041 H HA   . LEU B 1 288 ? 11.515  36.212  -1.248  0.33  14.498 ? 456 LEU D HA   1 c 
ATOM   8042 H HB2  . LEU B 1 288 ? 10.947  38.77   -2.379  0.33  15.365 ? 456 LEU D HB2  1 c 
ATOM   8043 H HB3  . LEU B 1 288 ? 12.23   38.498  -1.48   0.33  15.365 ? 456 LEU D HB3  1 c 
ATOM   8044 H HG   . LEU B 1 288 ? 11.781  37.265  -4.014  0.33  16.158 ? 456 LEU D HG   1 c 
ATOM   8045 H HD11 . LEU B 1 288 ? 12.276  39.526  -4.327  0.33  16.454 ? 456 LEU D HD11 1 c 
ATOM   8046 H HD12 . LEU B 1 288 ? 13.49   38.65   -4.853  0.33  16.454 ? 456 LEU D HD12 1 c 
ATOM   8047 H HD13 . LEU B 1 288 ? 13.591  39.386  -3.451  0.33  16.454 ? 456 LEU D HD13 1 c 
ATOM   8048 H HD21 . LEU B 1 288 ? 13.111  35.907  -2.687  0.33  16.32  ? 456 LEU D HD21 1 c 
ATOM   8049 H HD22 . LEU B 1 288 ? 14.115  37.107  -2.422  0.33  16.32  ? 456 LEU D HD22 1 c 
ATOM   8050 H HD23 . LEU B 1 288 ? 13.98   36.492  -3.878  0.33  16.32  ? 456 LEU D HD23 1 c 
ATOM   8051 N N    . ASP B 1 289 ? 9.465   36.494  0.519   0.33  13.101 ? 457 ASP D N    1 ? 
ATOM   8052 C CA   . ASP B 1 289 ? 8.599   36.871  1.621   0.33  13.207 ? 457 ASP D CA   1 ? 
ATOM   8053 C C    . ASP B 1 289 ? 8.894   36.032  2.863   0.33  12.288 ? 457 ASP D C    1 ? 
ATOM   8054 O O    . ASP B 1 289 ? 8.068   35.945  3.769   0.33  12.861 ? 457 ASP D O    1 ? 
ATOM   8055 C CB   . ASP B 1 289 ? 7.136   36.742  1.236   0.33  14.023 ? 457 ASP D CB   1 ? 
ATOM   8056 C CG   . ASP B 1 289 ? 6.697   35.318  0.934   0.33  14.84  ? 457 ASP D CG   1 ? 
ATOM   8057 O OD1  . ASP B 1 289 ? 7.568   34.5    0.697   0.33  14.219 ? 457 ASP D OD1  1 ? 
ATOM   8058 O OD2  . ASP B 1 289 ? 5.5     35.025  0.978   0.33  17.278 ? 457 ASP D OD2  1 ? 
ATOM   8059 H H    . ASP B 1 289 ? 9.462   35.626  0.234   0.33  13.29  ? 457 ASP D H    1 c 
ATOM   8060 H HA   . ASP B 1 289 ? 8.771   37.815  1.836   0.33  13.159 ? 457 ASP D HA   1 c 
ATOM   8061 H HB2  . ASP B 1 289 ? 6.584   37.087  1.969   0.33  14.013 ? 457 ASP D HB2  1 c 
ATOM   8062 H HB3  . ASP B 1 289 ? 6.967   37.292  0.443   0.33  14.013 ? 457 ASP D HB3  1 c 
ATOM   8063 N N    . ARG B 1 290 ? 10.092  35.456  2.928   0.33  12.582 ? 458 ARG D N    1 ? 
ATOM   8064 C CA   . ARG B 1 290 ? 10.435  34.516  3.986   0.33  12.434 ? 458 ARG D CA   1 ? 
ATOM   8065 C C    . ARG B 1 290 ? 11.911  34.163  3.853   0.33  11.804 ? 458 ARG D C    1 ? 
ATOM   8066 O O    . ARG B 1 290 ? 12.523  34.382  2.8     0.33  12.261 ? 458 ARG D O    1 ? 
ATOM   8067 C CB   . ARG B 1 290 ? 9.54    33.271  3.923   0.33  13.018 ? 458 ARG D CB   1 ? 
ATOM   8068 C CG   . ARG B 1 290 ? 9.87    32.373  2.747   0.33  14.351 ? 458 ARG D CG   1 ? 
ATOM   8069 C CD   . ARG B 1 290 ? 8.784   31.37   2.416   0.33  17.249 ? 458 ARG D CD   1 ? 
ATOM   8070 N NE   . ARG B 1 290 ? 7.552   32.015  1.945   0.33  20.019 ? 458 ARG D NE   1 ? 
ATOM   8071 C CZ   . ARG B 1 290 ? 6.323   31.648  2.279   0.33  23.28  ? 458 ARG D CZ   1 ? 
ATOM   8072 N NH1  . ARG B 1 290 ? 6.127   30.684  3.157   0.33  25.013 ? 458 ARG D NH1  1 ? 
ATOM   8073 N NH2  . ARG B 1 290 ? 5.282   32.252  1.731   0.33  24.788 ? 458 ARG D NH2  1 ? 
ATOM   8074 H H    . ARG B 1 290 ? 10.72   35.655  2.294   0.33  12.478 ? 458 ARG D H    1 c 
ATOM   8075 H HA   . ARG B 1 290 ? 10.295  34.965  4.858   0.33  12.448 ? 458 ARG D HA   1 c 
ATOM   8076 H HB2  . ARG B 1 290 ? 9.64    32.763  4.755   0.33  13.245 ? 458 ARG D HB2  1 c 
ATOM   8077 H HB3  . ARG B 1 290 ? 8.604   33.554  3.854   0.33  13.189 ? 458 ARG D HB3  1 c 
ATOM   8078 H HG2  . ARG B 1 290 ? 10.035  32.932  1.956   0.33  14.64  ? 458 ARG D HG2  1 c 
ATOM   8079 H HG3  . ARG B 1 290 ? 10.701  31.886  2.941   0.33  14.64  ? 458 ARG D HG3  1 c 
ATOM   8080 H HD2  . ARG B 1 290 ? 9.111   30.759  1.724   0.33  17.151 ? 458 ARG D HD2  1 c 
ATOM   8081 H HD3  . ARG B 1 290 ? 8.582   30.841  3.214   0.33  17.215 ? 458 ARG D HD3  1 c 
ATOM   8082 H HE   . ARG B 1 290 ? 7.631   32.692  1.404   0.33  20.046 ? 458 ARG D HE   1 c 
ATOM   8083 H HH11 . ARG B 1 290 ? 6.82    30.283  3.532   0.33  24.466 ? 458 ARG D HH11 1 c 
ATOM   8084 H HH12 . ARG B 1 290 ? 5.303   30.443  3.368   0.33  24.466 ? 458 ARG D HH12 1 c 
ATOM   8085 H HH21 . ARG B 1 290 ? 5.409   32.888  1.131   0.33  24.314 ? 458 ARG D HH21 1 c 
ATOM   8086 H HH22 . ARG B 1 290 ? 4.463   32.017  1.968   0.33  24.314 ? 458 ARG D HH22 1 c 
ATOM   8087 N N    . VAL B 1 291 ? 12.472  33.669  4.944   0.33  10.996 ? 459 VAL D N    1 ? 
ATOM   8088 C CA   . VAL B 1 291 ? 13.86   33.249  4.984   0.33  11.593 ? 459 VAL D CA   1 ? 
ATOM   8089 C C    . VAL B 1 291 ? 13.888  31.766  4.658   0.33  10.793 ? 459 VAL D C    1 ? 
ATOM   8090 O O    . VAL B 1 291 ? 13.848  30.949  5.577   0.33  10.828 ? 459 VAL D O    1 ? 
ATOM   8091 C CB   . VAL B 1 291 ? 14.502  33.519  6.361   0.33  12.269 ? 459 VAL D CB   1 ? 
ATOM   8092 C CG1  . VAL B 1 291 ? 15.984  33.142  6.37    0.33  12.15  ? 459 VAL D CG1  1 ? 
ATOM   8093 C CG2  . VAL B 1 291 ? 14.292  34.958  6.798   0.33  12.838 ? 459 VAL D CG2  1 ? 
ATOM   8094 H H    . VAL B 1 291 ? 11.968  33.588  5.702   0.33  11.318 ? 459 VAL D H    1 c 
ATOM   8095 H HA   . VAL B 1 291 ? 14.357  33.737  4.299   0.33  11.44  ? 459 VAL D HA   1 c 
ATOM   8096 H HB   . VAL B 1 291 ? 14.042  32.939  7.013   0.33  12.223 ? 459 VAL D HB   1 c 
ATOM   8097 H HG11 . VAL B 1 291 ? 16.458  33.674  5.71    0.33  12.185 ? 459 VAL D HG11 1 c 
ATOM   8098 H HG12 . VAL B 1 291 ? 16.08   32.199  6.156   0.33  12.185 ? 459 VAL D HG12 1 c 
ATOM   8099 H HG13 . VAL B 1 291 ? 16.357  33.312  7.251   0.33  12.185 ? 459 VAL D HG13 1 c 
ATOM   8100 H HG21 . VAL B 1 291 ? 14.706  35.098  7.666   0.33  12.667 ? 459 VAL D HG21 1 c 
ATOM   8101 H HG22 . VAL B 1 291 ? 13.34   35.144  6.86    0.33  12.667 ? 459 VAL D HG22 1 c 
ATOM   8102 H HG23 . VAL B 1 291 ? 14.696  35.557  6.148   0.33  12.667 ? 459 VAL D HG23 1 c 
ATOM   8103 N N    . THR B 1 292 ? 13.921  31.446  3.36    0.33  10.475 ? 460 THR D N    1 ? 
ATOM   8104 C CA   . THR B 1 292 ? 14.071  30.077  2.906   0.33  11.132 ? 460 THR D CA   1 ? 
ATOM   8105 C C    . THR B 1 292 ? 15.396  29.544  3.437   0.33  11.988 ? 460 THR D C    1 ? 
ATOM   8106 O O    . THR B 1 292 ? 16.432  30.206  3.379   0.33  10.692 ? 460 THR D O    1 ? 
ATOM   8107 C CB   . THR B 1 292 ? 13.997  29.968  1.386   0.33  10.898 ? 460 THR D CB   1 ? 
ATOM   8108 O OG1  . THR B 1 292 ? 12.743  30.51   1       0.33  11.308 ? 460 THR D OG1  1 ? 
ATOM   8109 C CG2  . THR B 1 292 ? 14.119  28.526  0.909   0.33  11.072 ? 460 THR D CG2  1 ? 
ATOM   8110 H H    . THR B 1 292 ? 13.846  32.11   2.736   0.33  10.696 ? 460 THR D H    1 c 
ATOM   8111 H HA   . THR B 1 292 ? 13.342  29.545  3.292   0.33  11.173 ? 460 THR D HA   1 c 
ATOM   8112 H HB   . THR B 1 292 ? 14.721  30.503  0.982   0.33  11.051 ? 460 THR D HB   1 c 
ATOM   8113 H HG21 . THR B 1 292 ? 14.066  28.5    -0.061  0.33  11.02  ? 460 THR D HG21 1 c 
ATOM   8114 H HG22 . THR B 1 292 ? 13.396  27.997  1.287   0.33  11.02  ? 460 THR D HG22 1 c 
ATOM   8115 H HG23 . THR B 1 292 ? 14.972  28.16   1.196   0.33  11.02  ? 460 THR D HG23 1 c 
ATOM   8116 N N    . VAL B 1 293 ? 15.323  28.318  3.953   0.33  12.723 ? 461 VAL D N    1 ? 
ATOM   8117 C CA   . VAL B 1 293 ? 16.485  27.554  4.335   0.33  12.469 ? 461 VAL D CA   1 ? 
ATOM   8118 C C    . VAL B 1 293 ? 16.385  26.229  3.59    0.33  12.378 ? 461 VAL D C    1 ? 
ATOM   8119 O O    . VAL B 1 293 ? 15.395  25.505  3.715   0.33  13.583 ? 461 VAL D O    1 ? 
ATOM   8120 C CB   . VAL B 1 293 ? 16.528  27.343  5.858   0.33  13.103 ? 461 VAL D CB   1 ? 
ATOM   8121 C CG1  . VAL B 1 293 ? 17.593  26.327  6.261   0.33  13.533 ? 461 VAL D CG1  1 ? 
ATOM   8122 C CG2  . VAL B 1 293 ? 16.692  28.658  6.601   0.33  13.223 ? 461 VAL D CG2  1 ? 
ATOM   8123 H H    . VAL B 1 293 ? 14.498  27.942  4.071   0.33  12.487 ? 461 VAL D H    1 c 
ATOM   8124 H HA   . VAL B 1 293 ? 17.29   28.028  4.049   0.33  12.614 ? 461 VAL D HA   1 c 
ATOM   8125 H HB   . VAL B 1 293 ? 15.655  26.972  6.117   0.33  13.13  ? 461 VAL D HB   1 c 
ATOM   8126 H HG11 . VAL B 1 293 ? 18.467  26.642  5.974   0.33  13.405 ? 461 VAL D HG11 1 c 
ATOM   8127 H HG12 . VAL B 1 293 ? 17.404  25.473  5.839   0.33  13.405 ? 461 VAL D HG12 1 c 
ATOM   8128 H HG13 . VAL B 1 293 ? 17.59   26.218  7.227   0.33  13.405 ? 461 VAL D HG13 1 c 
ATOM   8129 H HG21 . VAL B 1 293 ? 16.692  28.491  7.558   0.33  13.315 ? 461 VAL D HG21 1 c 
ATOM   8130 H HG22 . VAL B 1 293 ? 15.956  29.252  6.376   0.33  13.311 ? 461 VAL D HG22 1 c 
ATOM   8131 H HG23 . VAL B 1 293 ? 17.532  29.073  6.345   0.33  13.236 ? 461 VAL D HG23 1 c 
ATOM   8132 N N    . ASN B 1 294 ? 17.41   25.944  2.794   0.33  11.625 ? 462 ASN D N    1 ? 
ATOM   8133 C CA   . ASN B 1 294 ? 17.493  24.705  2.038   0.33  10.723 ? 462 ASN D CA   1 ? 
ATOM   8134 C C    . ASN B 1 294 ? 18.456  23.782  2.767   0.33  10.875 ? 462 ASN D C    1 ? 
ATOM   8135 O O    . ASN B 1 294 ? 19.668  23.904  2.629   0.33  10.686 ? 462 ASN D O    1 ? 
ATOM   8136 C CB   . ASN B 1 294 ? 17.935  24.951  0.602   0.33  10.895 ? 462 ASN D CB   1 ? 
ATOM   8137 C CG   . ASN B 1 294 ? 17.002  25.872  -0.147  0.33  11.233 ? 462 ASN D CG   1 ? 
ATOM   8138 O OD1  . ASN B 1 294 ? 15.916  25.466  -0.568  0.33  10.637 ? 462 ASN D OD1  1 ? 
ATOM   8139 N ND2  . ASN B 1 294 ? 17.416  27.119  -0.331  0.33  11.272 ? 462 ASN D ND2  1 ? 
ATOM   8140 H H    . ASN B 1 294 ? 18.091  26.549  2.716   0.33  11.587 ? 462 ASN D H    1 c 
ATOM   8141 H HA   . ASN B 1 294 ? 16.601  24.289  2.016   0.33  10.953 ? 462 ASN D HA   1 c 
ATOM   8142 H HB2  . ASN B 1 294 ? 18.832  25.341  0.606   0.33  10.932 ? 462 ASN D HB2  1 c 
ATOM   8143 H HB3  . ASN B 1 294 ? 17.982  24.095  0.131   0.33  10.932 ? 462 ASN D HB3  1 c 
ATOM   8144 H HD21 . ASN B 1 294 ? 16.904  27.695  -0.771  0.33  11.26  ? 462 ASN D HD21 1 c 
ATOM   8145 H HD22 . ASN B 1 294 ? 18.204  27.375  -0.014  0.33  11.26  ? 462 ASN D HD22 1 c 
ATOM   8146 N N    . ALA B 1 295 ? 17.912  22.858  3.563   0.33  10.934 ? 463 ALA D N    1 ? 
ATOM   8147 C CA   . ALA B 1 295 ? 18.746  22      4.381   0.33  11.641 ? 463 ALA D CA   1 ? 
ATOM   8148 C C    . ALA B 1 295 ? 19.767  21.248  3.526   0.33  11.942 ? 463 ALA D C    1 ? 
ATOM   8149 O O    . ALA B 1 295 ? 19.438  20.661  2.489   0.33  11.844 ? 463 ALA D O    1 ? 
ATOM   8150 C CB   . ALA B 1 295 ? 17.859  21.073  5.147   0.33  10.924 ? 463 ALA D CB   1 ? 
ATOM   8151 H H    . ALA B 1 295 ? 17.004  22.761  3.596   0.33  11.076 ? 463 ALA D H    1 c 
ATOM   8152 H HA   . ALA B 1 295 ? 19.245  22.575  5.024   0.33  11.418 ? 463 ALA D HA   1 c 
ATOM   8153 H HB1  . ALA B 1 295 ? 17.191  21.589  5.625   0.33  11.289 ? 463 ALA D HB1  1 c 
ATOM   8154 H HB2  . ALA B 1 295 ? 17.412  20.466  4.534   0.33  11.291 ? 463 ALA D HB2  1 c 
ATOM   8155 H HB3  . ALA B 1 295 ? 18.387  20.561  5.781   0.33  11.235 ? 463 ALA D HB3  1 c 
ATOM   8156 N N    . GLY B 1 296 ? 21.021  21.276  3.984   0.33  12.876 ? 464 GLY D N    1 ? 
ATOM   8157 C CA   . GLY B 1 296 ? 22.1    20.607  3.293   0.33  13.396 ? 464 GLY D CA   1 ? 
ATOM   8158 C C    . GLY B 1 296 ? 22.84   21.553  2.342   0.33  13.551 ? 464 GLY D C    1 ? 
ATOM   8159 O O    . GLY B 1 296 ? 23.983  21.285  1.974   0.33  13.921 ? 464 GLY D O    1 ? 
ATOM   8160 H H    . GLY B 1 296 ? 21.206  21.73   4.756   0.33  12.761 ? 464 GLY D H    1 c 
ATOM   8161 H HA2  . GLY B 1 296 ? 22.734  20.248  3.957   0.33  13.326 ? 464 GLY D HA2  1 c 
ATOM   8162 H HA3  . GLY B 1 296 ? 21.735  19.85   2.783   0.33  13.422 ? 464 GLY D HA3  1 c 
ATOM   8163 N N    . TRP B 1 297 ? 22.201  22.671  1.988   0.33  13.109 ? 465 TRP D N    1 ? 
ATOM   8164 C CA   . TRP B 1 297 ? 22.785  23.635  1.066   0.33  12.732 ? 465 TRP D CA   1 ? 
ATOM   8165 C C    . TRP B 1 297 ? 23.089  24.951  1.78    0.33  13.058 ? 465 TRP D C    1 ? 
ATOM   8166 O O    . TRP B 1 297 ? 24.113  25.568  1.52    0.33  14.594 ? 465 TRP D O    1 ? 
ATOM   8167 C CB   . TRP B 1 297 ? 21.841  23.845  -0.116  0.33  12.634 ? 465 TRP D CB   1 ? 
ATOM   8168 C CG   . TRP B 1 297 ? 21.61   22.57   -0.872  0.33  11.999 ? 465 TRP D CG   1 ? 
ATOM   8169 C CD1  . TRP B 1 297 ? 20.504  21.77   -0.86   0.33  11.991 ? 465 TRP D CD1  1 ? 
ATOM   8170 C CD2  . TRP B 1 297 ? 22.57   21.919  -1.723  0.33  12.279 ? 465 TRP D CD2  1 ? 
ATOM   8171 N NE1  . TRP B 1 297 ? 20.702  20.691  -1.677  0.33  12.625 ? 465 TRP D NE1  1 ? 
ATOM   8172 C CE2  . TRP B 1 297 ? 21.951  20.756  -2.226  0.33  12.54  ? 465 TRP D CE2  1 ? 
ATOM   8173 C CE3  . TRP B 1 297 ? 23.866  22.234  -2.134  0.33  12.287 ? 465 TRP D CE3  1 ? 
ATOM   8174 C CZ2  . TRP B 1 297 ? 22.604  19.898  -3.102  0.33  12.949 ? 465 TRP D CZ2  1 ? 
ATOM   8175 C CZ3  . TRP B 1 297 ? 24.514  21.378  -2.999  0.33  12.241 ? 465 TRP D CZ3  1 ? 
ATOM   8176 C CH2  . TRP B 1 297 ? 23.882  20.235  -3.482  0.33  12.509 ? 465 TRP D CH2  1 ? 
ATOM   8177 H H    . TRP B 1 297 ? 21.371  22.839  2.333   0.33  13.127 ? 465 TRP D H    1 c 
ATOM   8178 H HA   . TRP B 1 297 ? 23.639  23.258  0.721   0.33  12.845 ? 465 TRP D HA   1 c 
ATOM   8179 H HB2  . TRP B 1 297 ? 20.983  24.181  0.22    0.33  12.507 ? 465 TRP D HB2  1 c 
ATOM   8180 H HB3  . TRP B 1 297 ? 22.233  24.511  -0.72   0.33  12.507 ? 465 TRP D HB3  1 c 
ATOM   8181 H HD1  . TRP B 1 297 ? 19.707  21.939  -0.383  0.33  12.145 ? 465 TRP D HD1  1 c 
ATOM   8182 H HE1  . TRP B 1 297 ? 20.118  20.06   -1.825  0.33  12.451 ? 465 TRP D HE1  1 c 
ATOM   8183 H HE3  . TRP B 1 297 ? 24.293  23.011  -1.815  0.33  12.28  ? 465 TRP D HE3  1 c 
ATOM   8184 H HZ2  . TRP B 1 297 ? 22.185  19.118  -3.425  0.33  12.74  ? 465 TRP D HZ2  1 c 
ATOM   8185 H HZ3  . TRP B 1 297 ? 25.392  21.579  -3.282  0.33  12.319 ? 465 TRP D HZ3  1 c 
ATOM   8186 H HH2  . TRP B 1 297 ? 24.349  19.667  -4.069  0.33  12.544 ? 465 TRP D HH2  1 c 
ATOM   8187 N N    . ASP B 1 298 ? 22.21   25.354  2.691   0.33  13.114 ? 466 ASP D N    1 ? 
ATOM   8188 C CA   . ASP B 1 298 ? 22.387  26.585  3.439   0.33  13.359 ? 466 ASP D CA   1 ? 
ATOM   8189 C C    . ASP B 1 298 ? 22.946  26.247  4.81    0.33  14.271 ? 466 ASP D C    1 ? 
ATOM   8190 O O    . ASP B 1 298 ? 22.725  25.144  5.332   0.33  13.425 ? 466 ASP D O    1 ? 
ATOM   8191 C CB   . ASP B 1 298 ? 21.108  27.388  3.556   0.33  13.044 ? 466 ASP D CB   1 ? 
ATOM   8192 C CG   . ASP B 1 298 ? 20.531  27.836  2.228   0.33  13.032 ? 466 ASP D CG   1 ? 
ATOM   8193 O OD1  . ASP B 1 298 ? 21.325  28.223  1.347   0.33  12.584 ? 466 ASP D OD1  1 ? 
ATOM   8194 O OD2  . ASP B 1 298 ? 19.3    27.785  2.093   0.33  12.835 ? 466 ASP D OD2  1 ? 
ATOM   8195 H H    . ASP B 1 298 ? 21.471  24.843  2.855   0.33  13.155 ? 466 ASP D H    1 c 
ATOM   8196 H HA   . ASP B 1 298 ? 23.046  27.14   2.962   0.33  13.414 ? 466 ASP D HA   1 c 
ATOM   8197 H HB2  . ASP B 1 298 ? 20.434  26.845  4.017   0.33  13.113 ? 466 ASP D HB2  1 c 
ATOM   8198 H HB3  . ASP B 1 298 ? 21.282  28.184  4.101   0.33  13.113 ? 466 ASP D HB3  1 c 
ATOM   8199 N N    . PRO B 1 299 ? 23.688  27.2    5.417   0.33  15.354 ? 467 PRO D N    1 ? 
ATOM   8200 C CA   . PRO B 1 299 ? 24.298  26.972  6.719   0.33  16.44  ? 467 PRO D CA   1 ? 
ATOM   8201 C C    . PRO B 1 299 ? 23.213  26.797  7.771   0.33  16.006 ? 467 PRO D C    1 ? 
ATOM   8202 O O    . PRO B 1 299 ? 22.182  27.453  7.725   0.33  14.665 ? 467 PRO D O    1 ? 
ATOM   8203 C CB   . PRO B 1 299 ? 25.198  28.2    6.97    0.33  16.683 ? 467 PRO D CB   1 ? 
ATOM   8204 C CG   . PRO B 1 299 ? 24.836  29.225  5.908   0.33  16.724 ? 467 PRO D CG   1 ? 
ATOM   8205 C CD   . PRO B 1 299 ? 23.985  28.529  4.859   0.33  15.978 ? 467 PRO D CD   1 ? 
ATOM   8206 H HA   . PRO B 1 299 ? 24.857  26.156  6.674   0.33  16.186 ? 467 PRO D HA   1 c 
ATOM   8207 H HB2  . PRO B 1 299 ? 25.041  28.565  7.872   0.33  16.638 ? 467 PRO D HB2  1 c 
ATOM   8208 H HB3  . PRO B 1 299 ? 26.15   27.951  6.901   0.33  16.638 ? 467 PRO D HB3  1 c 
ATOM   8209 H HG2  . PRO B 1 299 ? 24.336  29.967  6.309   0.33  16.543 ? 467 PRO D HG2  1 c 
ATOM   8210 H HG3  . PRO B 1 299 ? 25.647  29.59   5.497   0.33  16.543 ? 467 PRO D HG3  1 c 
ATOM   8211 H HD2  . PRO B 1 299 ? 23.157  29.031  4.695   0.33  15.993 ? 467 PRO D HD2  1 c 
ATOM   8212 H HD3  . PRO B 1 299 ? 24.477  28.449  4.011   0.33  15.993 ? 467 PRO D HD3  1 c 
ATOM   8213 N N    . GLN B 1 300 ? 23.463  25.879  8.706   0.33  14.882 ? 468 GLN D N    1 ? 
ATOM   8214 C CA   . GLN B 1 300 ? 22.581  25.637  9.83    0.33  15.681 ? 468 GLN D CA   1 ? 
ATOM   8215 C C    . GLN B 1 300 ? 23.406  25.338  11.098  0.33  16.137 ? 468 GLN D C    1 ? 
ATOM   8216 O O    . GLN B 1 300 ? 22.87   25.581  12.195  0.33  18.598 ? 468 GLN D O    1 ? 
ATOM   8217 C CB   . GLN B 1 300 ? 21.657  24.476  9.471   0.33  14.012 ? 468 GLN D CB   1 ? 
ATOM   8218 C CG   . GLN B 1 300 ? 20.434  24.904  8.673   0.33  12.288 ? 468 GLN D CG   1 ? 
ATOM   8219 C CD   . GLN B 1 300 ? 19.569  23.727  8.287   0.33  10.901 ? 468 GLN D CD   1 ? 
ATOM   8220 O OE1  . GLN B 1 300 ? 19.997  22.869  7.512   0.33  10.469 ? 468 GLN D OE1  1 ? 
ATOM   8221 N NE2  . GLN B 1 300 ? 18.37   23.669  8.849   0.33  9.253  ? 468 GLN D NE2  1 ? 
ATOM   8222 O OXT  . GLN B 1 300 ? 24.565  24.88   10.947  0.33  16.659 ? 468 GLN D OXT  1 ? 
ATOM   8223 H H    . GLN B 1 300 ? 24.225  25.38   8.637   0.33  15.322 ? 468 GLN D H    1 c 
ATOM   8224 H HA   . GLN B 1 300 ? 22.039  26.452  9.985   0.33  15.285 ? 468 GLN D HA   1 c 
ATOM   8225 H HB2  . GLN B 1 300 ? 22.164  23.821  8.947   0.33  13.964 ? 468 GLN D HB2  1 c 
ATOM   8226 H HB3  . GLN B 1 300 ? 21.364  24.035  10.293  0.33  14.019 ? 468 GLN D HB3  1 c 
ATOM   8227 H HG2  . GLN B 1 300 ? 19.9    25.532  9.206   0.33  12.316 ? 468 GLN D HG2  1 c 
ATOM   8228 H HG3  . GLN B 1 300 ? 20.722  25.37   7.859   0.33  12.316 ? 468 GLN D HG3  1 c 
ATOM   8229 H HE21 . GLN B 1 300 ? 17.827  22.993  8.663   0.33  9.733  ? 468 GLN D HE21 1 c 
ATOM   8230 H HE22 . GLN B 1 300 ? 18.114  24.307  9.41    0.33  9.733  ? 468 GLN D HE22 1 c 
HETATM 8231 S S    . SO4 C 2 .   ? -8.361  15.547  6.877   1     29.493 ? 501 SO4 A S    1 ? 
HETATM 8232 O O1   . SO4 C 2 .   ? -9.591  16.302  6.786   1     31.123 ? 501 SO4 A O1   1 ? 
HETATM 8233 O O2   . SO4 C 2 .   ? -8.188  14.723  5.677   1     27.175 ? 501 SO4 A O2   1 ? 
HETATM 8234 O O3   . SO4 C 2 .   ? -8.413  14.683  8.03    1     33.627 ? 501 SO4 A O3   1 ? 
HETATM 8235 O O4   . SO4 C 2 .   ? -7.257  16.451  7       1     31.679 ? 501 SO4 A O4   1 ? 
HETATM 8236 S S    . SO4 D 2 .   ? 26.538  25.792  -16.555 0.33  36.662 ? 501 SO4 D S    1 ? 
HETATM 8237 O O1   . SO4 D 2 .   ? 27.773  25.111  -16.831 0.33  36.561 ? 501 SO4 D O1   1 ? 
HETATM 8238 O O2   . SO4 D 2 .   ? 25.521  25.34   -17.464 0.33  32.803 ? 501 SO4 D O2   1 ? 
HETATM 8239 O O3   . SO4 D 2 .   ? 26.72   27.212  -16.71  0.33  33.414 ? 501 SO4 D O3   1 ? 
HETATM 8240 O O4   . SO4 D 2 .   ? 26.138  25.5    -15.205 0.33  38.545 ? 501 SO4 D O4   1 ? 
HETATM 8241 O O    . HOH E 3 .   ? 12.918  25.736  12.474  1     34.558 ? 601 HOH A O    1 ? 
HETATM 8242 O O    . HOH E 3 .   ? 7.737   27.865  2.929   1     34.873 ? 602 HOH A O    1 ? 
HETATM 8243 O O    . HOH E 3 .   ? 9.546   30.042  9.527   1     29.035 ? 603 HOH A O    1 ? 
HETATM 8244 O O    . HOH E 3 .   ? -5.024  -6.295  25.605  1     30.984 ? 604 HOH A O    1 ? 
HETATM 8245 O O    . HOH E 3 .   ? 11.424  17.459  -3.974  1     46.148 ? 605 HOH A O    1 ? 
HETATM 8246 O O    . HOH E 3 .   ? -5.203  -8.046  18.611  1     31.619 ? 606 HOH A O    1 ? 
HETATM 8247 O O    . HOH E 3 .   ? 29.631  2.02    14.869  1     22.218 ? 607 HOH A O    1 ? 
HETATM 8248 O O    . HOH E 3 .   ? 0.494   -0.745  10.713  1     18.939 ? 608 HOH A O    1 ? 
HETATM 8249 O O    . HOH E 3 .   ? -1.949  24.128  0.032   1     25.417 ? 609 HOH A O    1 ? 
HETATM 8250 O O    . HOH E 3 .   ? -0      4.555   32.098  0.5   23.905 ? 610 HOH A O    1 ? 
HETATM 8251 O O    . HOH E 3 .   ? 27.753  11.715  9.377   1     46.961 ? 611 HOH A O    1 ? 
HETATM 8252 O O    . HOH E 3 .   ? 23.166  6.269   9.593   1     44.809 ? 612 HOH A O    1 ? 
HETATM 8253 O O    . HOH E 3 .   ? 12.51   27.082  3.974   1     30.311 ? 613 HOH A O    1 ? 
HETATM 8254 O O    . HOH E 3 .   ? 5.054   5.521   5.857   1     28.655 ? 614 HOH A O    1 ? 
HETATM 8255 O O    . HOH E 3 .   ? 9.333   24.142  2.29    1     23.121 ? 615 HOH A O    1 ? 
HETATM 8256 O O    . HOH E 3 .   ? 3.042   -2.549  33.840  1     19.87  ? 616 HOH A O    1 ? 
HETATM 8257 O O    . HOH E 3 .   ? 19.088  4.129   17.539  1     20.195 ? 617 HOH A O    1 ? 
HETATM 8258 O O    . HOH E 3 .   ? 7.603   25.383  18.298  1     24.171 ? 618 HOH A O    1 ? 
HETATM 8259 O O    . HOH E 3 .   ? 9.515   15.004  28.628  1     28.605 ? 619 HOH A O    1 ? 
HETATM 8260 O O    . HOH E 3 .   ? 26.006  -8.586  19.634  1     41.034 ? 620 HOH A O    1 ? 
HETATM 8261 O O    . HOH E 3 .   ? 28.416  -4.259  8.898   1     41.832 ? 621 HOH A O    1 ? 
HETATM 8262 O O    . HOH E 3 .   ? 9.983   15.074  37.374  1     37.884 ? 622 HOH A O    1 ? 
HETATM 8263 O O    . HOH E 3 .   ? 9.217   4.625   7.727   1     34.592 ? 623 HOH A O    1 ? 
HETATM 8264 O O    . HOH E 3 .   ? 3.033   16.435  8.905   1     18.749 ? 624 HOH A O    1 ? 
HETATM 8265 O O    . HOH E 3 .   ? -8.407  0.679   12.217  1     27.508 ? 625 HOH A O    1 ? 
HETATM 8266 O O    . HOH E 3 .   ? 16.163  16.549  30.774  1     38.448 ? 626 HOH A O    1 ? 
HETATM 8267 O O    . HOH E 3 .   ? 7.496   12.486  36.601  1     37.942 ? 627 HOH A O    1 ? 
HETATM 8268 O O    . HOH E 3 .   ? -4.672  24.443  10.589  1     22.866 ? 628 HOH A O    1 ? 
HETATM 8269 O O    . HOH E 3 .   ? 11.732  -9.148  2.070   1     28.538 ? 629 HOH A O    1 ? 
HETATM 8270 O O    . HOH E 3 .   ? 12.979  12.615  35.588  1     17.147 ? 630 HOH A O    1 ? 
HETATM 8271 O O    . HOH E 3 .   ? 8.924   16.452  -5.1    1     42.893 ? 631 HOH A O    1 ? 
HETATM 8272 O O    . HOH E 3 .   ? 1.912   22.033  -5.7    1     33.024 ? 632 HOH A O    1 ? 
HETATM 8273 O O    . HOH E 3 .   ? 29.272  0.779   21.241  1     20.601 ? 633 HOH A O    1 ? 
HETATM 8274 O O    . HOH E 3 .   ? 7.801   20.669  13.206  1     17.77  ? 634 HOH A O    1 ? 
HETATM 8275 O O    . HOH E 3 .   ? -2.432  10.21   28.793  1     40.638 ? 635 HOH A O    1 ? 
HETATM 8276 O O    . HOH E 3 .   ? 31.538  4.795   13.094  1     22.731 ? 636 HOH A O    1 ? 
HETATM 8277 O O    . HOH E 3 .   ? 19.583  12.323  0.668   1     33.132 ? 637 HOH A O    1 ? 
HETATM 8278 O O    . HOH E 3 .   ? 21.247  -11.214 24.276  1     39.102 ? 638 HOH A O    1 ? 
HETATM 8279 O O    . HOH E 3 .   ? 8.902   14.981  -2.054  1     27.654 ? 639 HOH A O    1 ? 
HETATM 8280 O O    . HOH E 3 .   ? 2.887   -2.057  6.982   1     30.609 ? 640 HOH A O    1 ? 
HETATM 8281 O O    . HOH E 3 .   ? 9.54    -17.697 20.077  1     44.263 ? 641 HOH A O    1 ? 
HETATM 8282 O O    . HOH E 3 .   ? 7.924   5.508   37.667  1     20.065 ? 642 HOH A O    1 ? 
HETATM 8283 O O    . HOH E 3 .   ? 15.945  5.685   38.459  1     16.596 ? 643 HOH A O    1 ? 
HETATM 8284 O O    . HOH E 3 .   ? 14.674  15.331  8.186   1     20.276 ? 644 HOH A O    1 ? 
HETATM 8285 O O    . HOH E 3 .   ? 11.983  -22.855 16.945  1     36.025 ? 645 HOH A O    1 ? 
HETATM 8286 O O    . HOH E 3 .   ? 7.877   -18.601 12.988  1     41.93  ? 646 HOH A O    1 ? 
HETATM 8287 O O    . HOH E 3 .   ? 8.856   7.990   -3.761  1     40.153 ? 647 HOH A O    1 ? 
HETATM 8288 O O    . HOH E 3 .   ? 22.373  0.771   16.641  1     24.023 ? 648 HOH A O    1 ? 
HETATM 8289 O O    . HOH E 3 .   ? -7.112  1.436   28.168  1     19.519 ? 649 HOH A O    1 ? 
HETATM 8290 O O    . HOH E 3 .   ? 3.781   10.236  30.919  1     23.789 ? 650 HOH A O    1 ? 
HETATM 8291 O O    . HOH E 3 .   ? 24.796  24.187  17.731  1     30.463 ? 651 HOH A O    1 ? 
HETATM 8292 O O    . HOH E 3 .   ? 26.755  19.238  27.356  1     27.622 ? 652 HOH A O    1 ? 
HETATM 8293 O O    . HOH E 3 .   ? 1.316   -15.938 14.68   1     19.117 ? 653 HOH A O    1 ? 
HETATM 8294 O O    . HOH E 3 .   ? 30.017  19.773  13.355  1     39.732 ? 654 HOH A O    1 ? 
HETATM 8295 O O    . HOH E 3 .   ? 23.03   7.773   22.867  1     13.246 ? 655 HOH A O    1 ? 
HETATM 8296 O O    . HOH E 3 .   ? 6.507   -0.327  6.427   1     31.079 ? 656 HOH A O    1 ? 
HETATM 8297 O O    . HOH E 3 .   ? 10.828  12.89   0.433   1     24.955 ? 657 HOH A O    1 ? 
HETATM 8298 O O    . HOH E 3 .   ? -1.223  -16.107 22.43   1     41.403 ? 658 HOH A O    1 ? 
HETATM 8299 O O    . HOH E 3 .   ? 29.993  7.637   20.363  1     17.768 ? 659 HOH A O    1 ? 
HETATM 8300 O O    . HOH E 3 .   ? 19.693  -14.261 21.856  1     40.145 ? 660 HOH A O    1 ? 
HETATM 8301 O O    . HOH E 3 .   ? 1.534   2.129   17.238  1     17.934 ? 661 HOH A O    1 ? 
HETATM 8302 O O    . HOH E 3 .   ? 19.193  -12.502 23.872  1     34.18  ? 662 HOH A O    1 ? 
HETATM 8303 O O    . HOH E 3 .   ? 6.138   -14.237 24.293  1     48.535 ? 663 HOH A O    1 ? 
HETATM 8304 O O    . HOH E 3 .   ? 6.391   11.372  12.901  1     18.293 ? 664 HOH A O    1 ? 
HETATM 8305 O O    . HOH E 3 .   ? 22.789  7.284   13.049  1     21.766 ? 665 HOH A O    1 ? 
HETATM 8306 O O    . HOH E 3 .   ? 3.705   -6.375  28.544  1     19.277 ? 666 HOH A O    1 ? 
HETATM 8307 O O    . HOH E 3 .   ? 15.186  -11.39  28.969  1     43.14  ? 667 HOH A O    1 ? 
HETATM 8308 O O    . HOH E 3 .   ? 7.747   -11.898 25.951  1     34.673 ? 668 HOH A O    1 ? 
HETATM 8309 O O    . HOH E 3 .   ? 18.582  7.996   4.757   1     31.285 ? 669 HOH A O    1 ? 
HETATM 8310 O O    . HOH E 3 .   ? 18.559  9.774   32.053  1     17.002 ? 670 HOH A O    1 ? 
HETATM 8311 O O    . HOH E 3 .   ? -11.493 5.83    9.156   1     37.919 ? 671 HOH A O    1 ? 
HETATM 8312 O O    . HOH E 3 .   ? 8.998   -2.033  6.725   1     36.18  ? 672 HOH A O    1 ? 
HETATM 8313 O O    . HOH E 3 .   ? 25.185  -1.783  21.634  1     31.348 ? 673 HOH A O    1 ? 
HETATM 8314 O O    . HOH E 3 .   ? 16.087  32.11   11.677  0.33  19.41  ? 674 HOH A O    1 ? 
HETATM 8315 O O    . HOH E 3 .   ? 29.594  22.262  14.228  1     35.497 ? 675 HOH A O    1 ? 
HETATM 8316 O O    . HOH E 3 .   ? 6.133   -7.842  4.543   1     35.451 ? 676 HOH A O    1 ? 
HETATM 8317 O O    . HOH E 3 .   ? -6.146  14.578  9.843   1     25.721 ? 677 HOH A O    1 ? 
HETATM 8318 O O    . HOH E 3 .   ? 16.186  -6.052  3.888   1     33.516 ? 678 HOH A O    1 ? 
HETATM 8319 O O    . HOH E 3 .   ? 22.934  16.598  7.352   1     28.412 ? 679 HOH A O    1 ? 
HETATM 8320 O O    . HOH E 3 .   ? -3.544  14.37   0.935   1     24.573 ? 680 HOH A O    1 ? 
HETATM 8321 O O    . HOH E 3 .   ? 20.64   -3.292  22.799  1     19.341 ? 681 HOH A O    1 ? 
HETATM 8322 O O    . HOH E 3 .   ? 22.384  -12.702 13.625  1     28.099 ? 682 HOH A O    1 ? 
HETATM 8323 O O    . HOH E 3 .   ? 6.116   25.505  22.183  1     31.745 ? 683 HOH A O    1 ? 
HETATM 8324 O O    . HOH E 3 .   ? -1.379  -20.461 13.067  1     35.642 ? 684 HOH A O    1 ? 
HETATM 8325 O O    . HOH E 3 .   ? 15.098  19.637  3.168   1     28.058 ? 685 HOH A O    1 ? 
HETATM 8326 O O    . HOH E 3 .   ? 11.93   5.794   39.558  1     16.985 ? 686 HOH A O    1 ? 
HETATM 8327 O O    . HOH E 3 .   ? 18.866  -19.15  21.656  1     33.418 ? 687 HOH A O    1 ? 
HETATM 8328 O O    . HOH E 3 .   ? 1.769   12.162  8.642   1     17.967 ? 688 HOH A O    1 ? 
HETATM 8329 O O    . HOH E 3 .   ? 25.931  10.301  10.586  1     31.619 ? 689 HOH A O    1 ? 
HETATM 8330 O O    . HOH E 3 .   ? 0.844   14.675  -6.435  1     18.605 ? 690 HOH A O    1 ? 
HETATM 8331 O O    . HOH E 3 .   ? -1.747  -6.513  24.188  1     17.584 ? 691 HOH A O    1 ? 
HETATM 8332 O O    . HOH E 3 .   ? 6.332   10.942  31.875  1     27.791 ? 692 HOH A O    1 ? 
HETATM 8333 O O    . HOH E 3 .   ? 11.147  6.352   10.067  1     30.38  ? 693 HOH A O    1 ? 
HETATM 8334 O O    . HOH E 3 .   ? 23.413  5.902   24.794  1     13.781 ? 694 HOH A O    1 ? 
HETATM 8335 O O    . HOH E 3 .   ? 2.064   23      15.741  1     22.525 ? 695 HOH A O    1 ? 
HETATM 8336 O O    . HOH E 3 .   ? 22.146  17.808  11.244  1     19.887 ? 696 HOH A O    1 ? 
HETATM 8337 O O    . HOH E 3 .   ? 20.898  5.701   10.832  1     43.189 ? 697 HOH A O    1 ? 
HETATM 8338 O O    . HOH E 3 .   ? 8.107   -11.933 30.298  1     42.809 ? 698 HOH A O    1 ? 
HETATM 8339 O O    . HOH E 3 .   ? -9.407  7.309   21.837  1     16.994 ? 699 HOH A O    1 ? 
HETATM 8340 O O    . HOH E 3 .   ? 9.715   -19.48  18.208  1     48.51  ? 700 HOH A O    1 ? 
HETATM 8341 O O    . HOH E 3 .   ? -9.25   2.28    21.73   1     22.864 ? 701 HOH A O    1 ? 
HETATM 8342 O O    . HOH E 3 .   ? -4.403  -4.31   13.869  1     32.248 ? 702 HOH A O    1 ? 
HETATM 8343 O O    . HOH E 3 .   ? -7.893  9.466   2.109   1     32.484 ? 703 HOH A O    1 ? 
HETATM 8344 O O    . HOH E 3 .   ? 18.811  1.716   32.924  1     22.077 ? 704 HOH A O    1 ? 
HETATM 8345 O O    . HOH E 3 .   ? -5.404  9.321   28.549  1     22.367 ? 705 HOH A O    1 ? 
HETATM 8346 O O    . HOH E 3 .   ? 29.061  18.351  19.285  1     31.595 ? 706 HOH A O    1 ? 
HETATM 8347 O O    . HOH E 3 .   ? 16.172  2.459   10.783  1     46.273 ? 707 HOH A O    1 ? 
HETATM 8348 O O    . HOH E 3 .   ? 7.307   11.166  -5.826  1     21.437 ? 708 HOH A O    1 ? 
HETATM 8349 O O    . HOH E 3 .   ? 3.264   0.124   30.732  1     18.181 ? 709 HOH A O    1 ? 
HETATM 8350 O O    . HOH E 3 .   ? -0.327  -0.165  7.357   1     39.426 ? 710 HOH A O    1 ? 
HETATM 8351 O O    . HOH E 3 .   ? -10.972 13.829  24.568  1     17.68  ? 711 HOH A O    1 ? 
HETATM 8352 O O    . HOH E 3 .   ? 25.503  19.975  19.6    1     21.662 ? 712 HOH A O    1 ? 
HETATM 8353 O O    . HOH E 3 .   ? -1.824  1.349   9.324   1     26.758 ? 713 HOH A O    1 ? 
HETATM 8354 O O    . HOH E 3 .   ? -6.78   1.816   1.079   1     35.53  ? 714 HOH A O    1 ? 
HETATM 8355 O O    . HOH E 3 .   ? 6.91    23.43   12.908  1     23.002 ? 715 HOH A O    1 ? 
HETATM 8356 O O    . HOH E 3 .   ? 5.359   -9.381  23.396  1     20.866 ? 716 HOH A O    1 ? 
HETATM 8357 O O    . HOH E 3 .   ? -7.293  18.474  8.864   1     25.625 ? 717 HOH A O    1 ? 
HETATM 8358 O O    . HOH E 3 .   ? 11.663  8.293   6.152   1     26.78  ? 718 HOH A O    1 ? 
HETATM 8359 O O    . HOH E 3 .   ? 10.046  20.237  2.798   1     21.824 ? 719 HOH A O    1 ? 
HETATM 8360 O O    . HOH E 3 .   ? 16.246  29.769  9.891   1     43.01  ? 720 HOH A O    1 ? 
HETATM 8361 O O    . HOH E 3 .   ? -0.079  21.678  16.652  1     30.193 ? 721 HOH A O    1 ? 
HETATM 8362 O O    . HOH E 3 .   ? 4.517   22.03   13.799  1     22.761 ? 722 HOH A O    1 ? 
HETATM 8363 O O    . HOH E 3 .   ? 16.198  9.564   30.576  1     16.645 ? 723 HOH A O    1 ? 
HETATM 8364 O O    . HOH E 3 .   ? -4.982  22.611  3.659   1     38.721 ? 724 HOH A O    1 ? 
HETATM 8365 O O    . HOH E 3 .   ? -4.598  2.605   10.938  1     18.53  ? 725 HOH A O    1 ? 
HETATM 8366 O O    . HOH E 3 .   ? -5.743  1.809   23.889  1     18.446 ? 726 HOH A O    1 ? 
HETATM 8367 O O    . HOH E 3 .   ? -0.686  16.476  19.221  1     19.251 ? 727 HOH A O    1 ? 
HETATM 8368 O O    . HOH E 3 .   ? -0.761  -1.288  29.216  1     19.681 ? 728 HOH A O    1 ? 
HETATM 8369 O O    . HOH E 3 .   ? -5.762  12.978  1.814   1     28.054 ? 729 HOH A O    1 ? 
HETATM 8370 O O    . HOH E 3 .   ? -2.621  9.813   -4.547  1     32.436 ? 730 HOH A O    1 ? 
HETATM 8371 O O    . HOH E 3 .   ? -3.778  -5.716  19.788  1     30.618 ? 731 HOH A O    1 ? 
HETATM 8372 O O    . HOH E 3 .   ? 17.45   -2.862  14.878  1     15.348 ? 732 HOH A O    1 ? 
HETATM 8373 O O    . HOH E 3 .   ? 20.449  -5.562  27.763  1     27.174 ? 733 HOH A O    1 ? 
HETATM 8374 O O    . HOH E 3 .   ? -11.67  14.832  7.93    1     26.741 ? 734 HOH A O    1 ? 
HETATM 8375 O O    . HOH E 3 .   ? -0.586  -7.556  6.627   1     34.61  ? 735 HOH A O    1 ? 
HETATM 8376 O O    . HOH E 3 .   ? 10.049  -16.283 24.755  1     25.324 ? 736 HOH A O    1 ? 
HETATM 8377 O O    . HOH E 3 .   ? 20.874  -16.38  11.461  1     29.818 ? 737 HOH A O    1 ? 
HETATM 8378 O O    . HOH E 3 .   ? 27.124  -5.981  13.927  1     34.915 ? 738 HOH A O    1 ? 
HETATM 8379 O O    . HOH E 3 .   ? 18.563  -0.256  34.74   1     38.362 ? 739 HOH A O    1 ? 
HETATM 8380 O O    . HOH E 3 .   ? 21.63   -0.101  19.24   1     21.068 ? 740 HOH A O    1 ? 
HETATM 8381 O O    . HOH E 3 .   ? -9.936  12.066  5.546   1     44.051 ? 741 HOH A O    1 ? 
HETATM 8382 O O    . HOH E 3 .   ? 6.526   1.064   12.847  1     18.569 ? 742 HOH A O    1 ? 
HETATM 8383 O O    . HOH E 3 .   ? -0.203  7.351   6.618   1     32.6   ? 743 HOH A O    1 ? 
HETATM 8384 O O    . HOH E 3 .   ? 19.603  -2.337  33.157  1     39.687 ? 744 HOH A O    1 ? 
HETATM 8385 O O    . HOH E 3 .   ? 26.821  -7.836  15.995  1     29.294 ? 745 HOH A O    1 ? 
HETATM 8386 O O    . HOH E 3 .   ? 21.768  14.198  28.616  1     22.133 ? 746 HOH A O    1 ? 
HETATM 8387 O O    . HOH E 3 .   ? -7.417  13.041  11.832  1     20.663 ? 747 HOH A O    1 ? 
HETATM 8388 O O    . HOH E 3 .   ? -2.492  -8.196  8.29    1     27.332 ? 748 HOH A O    1 ? 
HETATM 8389 O O    . HOH E 3 .   ? -5.887  -14.338 18.291  1     38.686 ? 749 HOH A O    1 ? 
HETATM 8390 O O    . HOH E 3 .   ? 31.021  15.114  19.757  1     31.638 ? 750 HOH A O    1 ? 
HETATM 8391 O O    . HOH E 3 .   ? 26.041  8.993   28.245  1     14.446 ? 751 HOH A O    1 ? 
HETATM 8392 O O    . HOH E 3 .   ? -8.131  14.503  15.318  1     34.354 ? 752 HOH A O    1 ? 
HETATM 8393 O O    . HOH E 3 .   ? 10.612  -9.5    23.732  1     18.328 ? 753 HOH A O    1 ? 
HETATM 8394 O O    . HOH E 3 .   ? 27.057  16.166  19.049  1     21.466 ? 754 HOH A O    1 ? 
HETATM 8395 O O    . HOH E 3 .   ? 11.798  13.327  29.876  1     19.189 ? 755 HOH A O    1 ? 
HETATM 8396 O O    . HOH E 3 .   ? 8.632   -3.948  32.045  1     16.787 ? 756 HOH A O    1 ? 
HETATM 8397 O O    . HOH E 3 .   ? 4.282   26.417  1.768   1     22.978 ? 757 HOH A O    1 ? 
HETATM 8398 O O    . HOH E 3 .   ? 0.643   9.793   28.739  1     26.463 ? 758 HOH A O    1 ? 
HETATM 8399 O O    . HOH E 3 .   ? -1.017  18.697  -6.511  1     33.812 ? 759 HOH A O    1 ? 
HETATM 8400 O O    . HOH E 3 .   ? 20.445  -13.469 8.598   1     31.272 ? 760 HOH A O    1 ? 
HETATM 8401 O O    . HOH E 3 .   ? 8.862   -9.294  25.732  1     19.947 ? 761 HOH A O    1 ? 
HETATM 8402 O O    . HOH E 3 .   ? 25.693  17.718  20.934  1     20.922 ? 762 HOH A O    1 ? 
HETATM 8403 O O    . HOH E 3 .   ? 3.01    24.242  -4.85   1     22.946 ? 763 HOH A O    1 ? 
HETATM 8404 O O    A HOH E 3 .   ? 20.678  16.438  31.181  0.5   32.015 ? 764 HOH A O    1 ? 
HETATM 8405 O O    B HOH E 3 .   ? 21.233  17.67   31.337  0.5   24.561 ? 764 HOH A O    1 ? 
HETATM 8406 O O    . HOH E 3 .   ? 27.5    18.969  13.607  1     31.777 ? 765 HOH A O    1 ? 
HETATM 8407 O O    . HOH E 3 .   ? 25.042  -4.979  6.511   1     34.302 ? 766 HOH A O    1 ? 
HETATM 8408 O O    . HOH E 3 .   ? 0.122   -13.238 23.232  1     33.794 ? 767 HOH A O    1 ? 
HETATM 8409 O O    . HOH E 3 .   ? -8.91   13.873  18.187  1     23.494 ? 768 HOH A O    1 ? 
HETATM 8410 O O    . HOH E 3 .   ? 2.727   -17.257 22.318  1     36.992 ? 769 HOH A O    1 ? 
HETATM 8411 O O    . HOH E 3 .   ? 9.884   2.625   9.321   1     29.067 ? 770 HOH A O    1 ? 
HETATM 8412 O O    . HOH E 3 .   ? -2.017  -11.304 6.919   1     22.421 ? 771 HOH A O    1 ? 
HETATM 8413 O O    . HOH E 3 .   ? 17.352  0.829   15.974  1     20.787 ? 772 HOH A O    1 ? 
HETATM 8414 O O    . HOH E 3 .   ? 29.935  -1.304  14.98   1     47.421 ? 773 HOH A O    1 ? 
HETATM 8415 O O    . HOH E 3 .   ? 7.344   -18.99  16.662  1     41.807 ? 774 HOH A O    1 ? 
HETATM 8416 O O    . HOH E 3 .   ? -2.964  -5.613  9.642   1     38.263 ? 775 HOH A O    1 ? 
HETATM 8417 O O    . HOH E 3 .   ? -10.13  4.844   20.766  1     19.145 ? 776 HOH A O    1 ? 
HETATM 8418 O O    . HOH E 3 .   ? -1.861  16.2    22.677  1     41.509 ? 777 HOH A O    1 ? 
HETATM 8419 O O    . HOH E 3 .   ? 1.174   1.835   9.938   1     24.933 ? 778 HOH A O    1 ? 
HETATM 8420 O O    . HOH E 3 .   ? 0.258   6.279   29.243  1     33.584 ? 779 HOH A O    1 ? 
HETATM 8421 O O    . HOH E 3 .   ? 10.165  -11.369 5.246   1     28.482 ? 780 HOH A O    1 ? 
HETATM 8422 O O    . HOH E 3 .   ? 22.689  -1.051  27.09   1     36.073 ? 781 HOH A O    1 ? 
HETATM 8423 O O    . HOH E 3 .   ? 13.899  13.016  31.626  1     19.798 ? 782 HOH A O    1 ? 
HETATM 8424 O O    . HOH E 3 .   ? 16.17   13.167  30.385  1     21.814 ? 783 HOH A O    1 ? 
HETATM 8425 O O    . HOH E 3 .   ? -4.327  1.868   7.538   1     35.438 ? 784 HOH A O    1 ? 
HETATM 8426 O O    . HOH E 3 .   ? 2.805   5.182   31.889  1     23.326 ? 785 HOH A O    1 ? 
HETATM 8427 O O    . HOH E 3 .   ? 15.084  -12.034 -0.604  1     26.703 ? 786 HOH A O    1 ? 
HETATM 8428 O O    . HOH E 3 .   ? 7.237   -18.089 19.035  1     31.16  ? 787 HOH A O    1 ? 
HETATM 8429 O O    . HOH E 3 .   ? 15.389  25.997  12.834  1     25.077 ? 788 HOH A O    1 ? 
HETATM 8430 O O    . HOH E 3 .   ? 18.66   -20.422 16.261  1     37.171 ? 789 HOH A O    1 ? 
HETATM 8431 O O    . HOH E 3 .   ? -9.757  -0.799  23.904  1     27.359 ? 790 HOH A O    1 ? 
HETATM 8432 O O    . HOH E 3 .   ? 25.615  15.868  30.566  1     28.36  ? 791 HOH A O    1 ? 
HETATM 8433 O O    . HOH E 3 .   ? 7.863   18.055  -6.933  1     41.708 ? 792 HOH A O    1 ? 
HETATM 8434 O O    . HOH E 3 .   ? 24.214  -1.258  24.948  1     28.648 ? 793 HOH A O    1 ? 
HETATM 8435 O O    . HOH E 3 .   ? 11.515  -2.624  36.119  1     25.304 ? 794 HOH A O    1 ? 
HETATM 8436 O O    . HOH E 3 .   ? 10.481  -6.152  31.958  1     23.004 ? 795 HOH A O    1 ? 
HETATM 8437 O O    . HOH E 3 .   ? -6.011  17.241  25.055  1     52.167 ? 796 HOH A O    1 ? 
HETATM 8438 O O    . HOH E 3 .   ? 22.924  -15.369 18.445  1     43.886 ? 797 HOH A O    1 ? 
HETATM 8439 O O    . HOH E 3 .   ? 22.093  10.974  3.197   1     52.492 ? 798 HOH A O    1 ? 
HETATM 8440 O O    . HOH E 3 .   ? 17.679  -3.368  34.668  1     32.117 ? 799 HOH A O    1 ? 
HETATM 8441 O O    . HOH E 3 .   ? -2.276  -17.629 10.897  1     37.606 ? 800 HOH A O    1 ? 
HETATM 8442 O O    . HOH E 3 .   ? 9.74    6.593   5.384   1     24.942 ? 801 HOH A O    1 ? 
HETATM 8443 O O    . HOH E 3 .   ? 7.144   2.195   10.519  1     21.758 ? 802 HOH A O    1 ? 
HETATM 8444 O O    . HOH E 3 .   ? 23.545  18.137  13.59   1     21.824 ? 803 HOH A O    1 ? 
HETATM 8445 O O    . HOH E 3 .   ? 2.895   6.102   29.157  1     30.827 ? 804 HOH A O    1 ? 
HETATM 8446 O O    . HOH E 3 .   ? 4.045   18.469  30.146  1     30.842 ? 805 HOH A O    1 ? 
HETATM 8447 O O    . HOH E 3 .   ? -1.365  13.53   -5.476  1     18.865 ? 806 HOH A O    1 ? 
HETATM 8448 O O    . HOH E 3 .   ? 22.029  -0.911  23.283  1     31.427 ? 807 HOH A O    1 ? 
HETATM 8449 O O    . HOH E 3 .   ? 25.599  9.063   7.862   1     34.903 ? 808 HOH A O    1 ? 
HETATM 8450 O O    . HOH E 3 .   ? 27.781  7.437   24.669  1     19.168 ? 809 HOH A O    1 ? 
HETATM 8451 O O    . HOH E 3 .   ? 5.97    -19.139 10.6    1     38.544 ? 810 HOH A O    1 ? 
HETATM 8452 O O    . HOH E 3 .   ? -4.386  -13.884 10.721  1     24.193 ? 811 HOH A O    1 ? 
HETATM 8453 O O    . HOH E 3 .   ? 14.997  -2.75   8.598   1     40.95  ? 812 HOH A O    1 ? 
HETATM 8454 O O    . HOH E 3 .   ? 27.804  15.228  6.574   1     50.471 ? 813 HOH A O    1 ? 
HETATM 8455 O O    . HOH E 3 .   ? -6.313  -12.323 13.216  1     21.908 ? 814 HOH A O    1 ? 
HETATM 8456 O O    . HOH E 3 .   ? 0.932   -16.952 7.785   1     27.553 ? 815 HOH A O    1 ? 
HETATM 8457 O O    . HOH E 3 .   ? -5.974  18.537  0.461   1     44.031 ? 816 HOH A O    1 ? 
HETATM 8458 O O    . HOH E 3 .   ? 22.102  -18.66  14.87   1     47.337 ? 817 HOH A O    1 ? 
HETATM 8459 O O    . HOH E 3 .   ? -9.582  19.128  5.627   1     42.7   ? 818 HOH A O    1 ? 
HETATM 8460 O O    . HOH E 3 .   ? 6.993   4.178   6.571   1     44.611 ? 819 HOH A O    1 ? 
HETATM 8461 O O    . HOH E 3 .   ? 7.179   -16.831 9.975   1     24.502 ? 820 HOH A O    1 ? 
HETATM 8462 O O    . HOH E 3 .   ? 17.048  -14.671 5.318   1     44.494 ? 821 HOH A O    1 ? 
HETATM 8463 O O    . HOH E 3 .   ? -4.907  -1.875  9.841   1     57.131 ? 822 HOH A O    1 ? 
HETATM 8464 O O    . HOH E 3 .   ? 29.333  19.471  6.935   1     41.443 ? 823 HOH A O    1 ? 
HETATM 8465 O O    . HOH E 3 .   ? 16.505  -13.742 27.318  1     44.374 ? 824 HOH A O    1 ? 
HETATM 8466 O O    . HOH E 3 .   ? 24.327  8.105   10.771  1     45.586 ? 825 HOH A O    1 ? 
HETATM 8467 O O    . HOH E 3 .   ? 26.149  -12.801 9.924   1     45.881 ? 826 HOH A O    1 ? 
HETATM 8468 O O    . HOH E 3 .   ? 10.509  23.421  -0.084  1     43.773 ? 827 HOH A O    1 ? 
HETATM 8469 O O    . HOH E 3 .   ? -5.515  -3.605  16.034  1     35.463 ? 828 HOH A O    1 ? 
HETATM 8470 O O    . HOH E 3 .   ? -9.405  12.558  10.106  1     33.479 ? 829 HOH A O    1 ? 
HETATM 8471 O O    . HOH E 3 .   ? 10.46   15.772  0.331   1     33.446 ? 830 HOH A O    1 ? 
HETATM 8472 O O    . HOH E 3 .   ? 20.92   3.442   32.098  0.5   24.561 ? 831 HOH A O    1 ? 
HETATM 8473 O O    . HOH E 3 .   ? 29.652  2.126   23.490  1     21.099 ? 832 HOH A O    1 ? 
HETATM 8474 O O    . HOH E 3 .   ? 29.584  4.509   22.13   1     16.646 ? 833 HOH A O    1 ? 
HETATM 8475 O O    . HOH E 3 .   ? 1.524   27.597  -1.768  1     50.134 ? 834 HOH A O    1 ? 
HETATM 8476 O O    . HOH E 3 .   ? -3.454  6.381   29.452  1     29.153 ? 835 HOH A O    1 ? 
HETATM 8477 O O    . HOH E 3 .   ? -7.431  14.431  26.039  1     41.193 ? 836 HOH A O    1 ? 
HETATM 8478 O O    . HOH E 3 .   ? 7.569   17.674  30.554  1     37.782 ? 837 HOH A O    1 ? 
HETATM 8479 O O    . HOH E 3 .   ? 6.26    25.641  14.345  1     36.527 ? 838 HOH A O    1 ? 
HETATM 8480 O O    . HOH E 3 .   ? 28.313  -0.824  10.792  1     48.062 ? 839 HOH A O    1 ? 
HETATM 8481 O O    . HOH E 3 .   ? 0.75    0.124   30.983  1     22.365 ? 840 HOH A O    1 ? 
HETATM 8482 O O    . HOH E 3 .   ? 5.443   28.662  13.131  0.33  27.549 ? 841 HOH A O    1 ? 
HETATM 8483 O O    . HOH E 3 .   ? 22.323  -5.164  23.828  1     29.801 ? 842 HOH A O    1 ? 
HETATM 8484 O O    . HOH E 3 .   ? 17.409  13.63   0.961   1     45.197 ? 843 HOH A O    1 ? 
HETATM 8485 O O    . HOH E 3 .   ? 3.722   -13.805 24.061  1     39.164 ? 844 HOH A O    1 ? 
HETATM 8486 O O    . HOH E 3 .   ? 28.006  14.547  30.515  1     25.506 ? 845 HOH A O    1 ? 
HETATM 8487 O O    . HOH E 3 .   ? 10.727  26.695  2.35    1     34.697 ? 846 HOH A O    1 ? 
HETATM 8488 O O    . HOH E 3 .   ? 6.492   -8.169  25.543  1     20.816 ? 847 HOH A O    1 ? 
HETATM 8489 O O    . HOH E 3 .   ? 26.252  -7.872  24.542  1     54.285 ? 848 HOH A O    1 ? 
HETATM 8490 O O    . HOH E 3 .   ? 19.364  1.205   17.988  1     23.263 ? 849 HOH A O    1 ? 
HETATM 8491 O O    . HOH E 3 .   ? 13.462  -5.004  35.514  1     37.333 ? 850 HOH A O    1 ? 
HETATM 8492 O O    . HOH E 3 .   ? 26.477  1.541   9.328   1     56.495 ? 851 HOH A O    1 ? 
HETATM 8493 O O    . HOH E 3 .   ? -5.515  24.619  13.42   1     35.452 ? 852 HOH A O    1 ? 
HETATM 8494 O O    . HOH E 3 .   ? 14.767  5.957   4.792   1     42.011 ? 853 HOH A O    1 ? 
HETATM 8495 O O    . HOH E 3 .   ? 29.043  17.728  23.954  1     36.221 ? 854 HOH A O    1 ? 
HETATM 8496 O O    . HOH E 3 .   ? 12.152  16.62   33.583  1     42.494 ? 855 HOH A O    1 ? 
HETATM 8497 O O    . HOH E 3 .   ? 4.129   -4.852  30.663  1     26.205 ? 856 HOH A O    1 ? 
HETATM 8498 O O    . HOH E 3 .   ? -7.642  -4.868  19.612  1     40.475 ? 857 HOH A O    1 ? 
HETATM 8499 O O    . HOH E 3 .   ? 26.545  21.211  11.835  1     40.907 ? 858 HOH A O    1 ? 
HETATM 8500 O O    . HOH E 3 .   ? -8.095  17.21   2.05    1     54.926 ? 859 HOH A O    1 ? 
HETATM 8501 O O    . HOH E 3 .   ? 33.400  20.680  7.812   1     30.896 ? 860 HOH A O    1 ? 
HETATM 8502 O O    . HOH E 3 .   ? 12.536  -6.371  32.871  1     46.67  ? 861 HOH A O    1 ? 
HETATM 8503 O O    . HOH E 3 .   ? 24.75   -4.243  22.369  1     32.455 ? 862 HOH A O    1 ? 
HETATM 8504 O O    . HOH E 3 .   ? 25.041  21.481  27.61   1     43.121 ? 863 HOH A O    1 ? 
HETATM 8505 O O    . HOH E 3 .   ? 16.162  -5.591  34.518  1     42.523 ? 864 HOH A O    1 ? 
HETATM 8506 O O    . HOH E 3 .   ? -5.223  -4.189  18.471  1     36.798 ? 865 HOH A O    1 ? 
HETATM 8507 O O    . HOH E 3 .   ? 23.285  25.487  19.601  1     36.726 ? 866 HOH A O    1 ? 
HETATM 8508 O O    . HOH E 3 .   ? -8.55   -12.787 14.686  1     40.837 ? 867 HOH A O    1 ? 
HETATM 8509 O O    . HOH E 3 .   ? -3.312  24.408  2.618   1     36.171 ? 868 HOH A O    1 ? 
HETATM 8510 O O    . HOH E 3 .   ? 18.671  12.662  32.11   1     36.007 ? 869 HOH A O    1 ? 
HETATM 8511 O O    . HOH E 3 .   ? -0.724  21.7    -5.831  1     43.862 ? 870 HOH A O    1 ? 
HETATM 8512 O O    . HOH E 3 .   ? 9.792   1.838   39.954  1     24.619 ? 871 HOH A O    1 ? 
HETATM 8513 O O    . HOH E 3 .   ? 12.787  23.187  2.352   1     41.554 ? 872 HOH A O    1 ? 
HETATM 8514 O O    . HOH E 3 .   ? 0.741   -10.807 24.18   1     28.786 ? 873 HOH A O    1 ? 
HETATM 8515 O O    . HOH E 3 .   ? -3.107  8.755   30.855  1     37.103 ? 874 HOH A O    1 ? 
HETATM 8516 O O    . HOH E 3 .   ? -8.441  -13.486 18.181  1     51.095 ? 875 HOH A O    1 ? 
HETATM 8517 O O    . HOH E 3 .   ? 6.718   -9.293  30.327  1     33.194 ? 876 HOH A O    1 ? 
HETATM 8518 O O    . HOH E 3 .   ? -4.911  15.967  -0.929  1     28.276 ? 877 HOH A O    1 ? 
HETATM 8519 O O    . HOH E 3 .   ? -4.777  -7.347  13.947  1     31.119 ? 878 HOH A O    1 ? 
HETATM 8520 O O    . HOH E 3 .   ? 12.613  12.286  -1.051  1     45.666 ? 879 HOH A O    1 ? 
HETATM 8521 O O    . HOH E 3 .   ? 24.777  -13.745 13.836  1     46.251 ? 880 HOH A O    1 ? 
HETATM 8522 O O    . HOH E 3 .   ? 21.943  13.164  -0.571  1     42.344 ? 881 HOH A O    1 ? 
HETATM 8523 O O    . HOH E 3 .   ? 6.04    1.697   7.856   1     32.285 ? 882 HOH A O    1 ? 
HETATM 8524 O O    . HOH E 3 .   ? -6.694  -9.762  12.402  1     45.917 ? 883 HOH A O    1 ? 
HETATM 8525 O O    . HOH E 3 .   ? 20.144  -9.192  -1.098  1     40.05  ? 884 HOH A O    1 ? 
HETATM 8526 O O    . HOH E 3 .   ? 9.466   -3.525  34.630  1     23.795 ? 885 HOH A O    1 ? 
HETATM 8527 O O    . HOH E 3 .   ? 1.12    12.243  28.07   1     47.921 ? 886 HOH A O    1 ? 
HETATM 8528 O O    . HOH E 3 .   ? -4.344  -18.442 16.972  1     48.241 ? 887 HOH A O    1 ? 
HETATM 8529 O O    . HOH E 3 .   ? -1.934  20.971  -3.058  1     39.415 ? 888 HOH A O    1 ? 
HETATM 8530 O O    . HOH E 3 .   ? 8.434   31.994  10.492  0.33  19.723 ? 889 HOH A O    1 ? 
HETATM 8531 O O    . HOH E 3 .   ? 25.231  -10.097 25.434  1     55.172 ? 890 HOH A O    1 ? 
HETATM 8532 O O    . HOH E 3 .   ? 5.213   -8.641  28.053  1     23.8   ? 891 HOH A O    1 ? 
HETATM 8533 O O    . HOH E 3 .   ? 6.331   5.688   0.296   1     44.771 ? 892 HOH A O    1 ? 
HETATM 8534 O O    . HOH E 3 .   ? -7.604  2.655   25.777  1     15.312 ? 893 HOH A O    1 ? 
HETATM 8535 O O    . HOH E 3 .   ? 16.227  6.395   6.938   1     47.77  ? 894 HOH A O    1 ? 
HETATM 8536 O O    . HOH E 3 .   ? 9.228   -7.778  33.573  1     41.23  ? 895 HOH A O    1 ? 
HETATM 8537 O O    . HOH E 3 .   ? 18.204  -21.664 18.469  1     58.616 ? 896 HOH A O    1 ? 
HETATM 8538 O O    . HOH E 3 .   ? 2.011   -3.685  31.624  1     31.212 ? 897 HOH A O    1 ? 
HETATM 8539 O O    . HOH E 3 .   ? -0.369  18.402  21.215  1     35.102 ? 898 HOH A O    1 ? 
HETATM 8540 O O    . HOH E 3 .   ? 4.283   5.311   1.774   1     48.168 ? 899 HOH A O    1 ? 
HETATM 8541 O O    . HOH E 3 .   ? 30.702  1.089   12.478  1     42.887 ? 900 HOH A O    1 ? 
HETATM 8542 O O    . HOH E 3 .   ? 1.765   -15.03  25.49   1     51.305 ? 901 HOH A O    1 ? 
HETATM 8543 O O    . HOH E 3 .   ? -6.049  -5.703  27.718  1     50.87  ? 902 HOH A O    1 ? 
HETATM 8544 O O    . HOH E 3 .   ? 7.063   -7.945  32.345  1     35.254 ? 903 HOH A O    1 ? 
HETATM 8545 O O    . HOH E 3 .   ? 25.642  22.408  20.592  1     33.851 ? 904 HOH A O    1 ? 
HETATM 8546 O O    . HOH E 3 .   ? 27.766  -1.578  21.645  1     26.39  ? 905 HOH A O    1 ? 
HETATM 8547 O O    . HOH E 3 .   ? 3.347   2.035   7.938   1     39.549 ? 906 HOH A O    1 ? 
HETATM 8548 O O    . HOH E 3 .   ? 0.511   16.343  27.775  1     37.25  ? 907 HOH A O    1 ? 
HETATM 8549 O O    . HOH E 3 .   ? -7.190  25.013  9.321   0.33  14.676 ? 908 HOH A O    1 ? 
HETATM 8550 O O    . HOH E 3 .   ? 30.297  -2.270  25.322  1     35.727 ? 909 HOH A O    1 ? 
HETATM 8551 O O    . HOH E 3 .   ? -7.736  -6.101  21.964  1     49.978 ? 910 HOH A O    1 ? 
HETATM 8552 O O    . HOH E 3 .   ? 9.477   6.965   39.73   1     17.536 ? 911 HOH A O    1 ? 
HETATM 8553 O O    . HOH E 3 .   ? 24.262  1.962   8.495   1     59.827 ? 912 HOH A O    1 ? 
HETATM 8554 O O    . HOH E 3 .   ? 4.393   -4.903  34.489  1     25.894 ? 913 HOH A O    1 ? 
HETATM 8555 O O    . HOH E 3 .   ? -4.014  -12.066 8.523   1     27.039 ? 914 HOH A O    1 ? 
HETATM 8556 O O    . HOH E 3 .   ? 0.826   -6.056  28.305  1     43.265 ? 915 HOH A O    1 ? 
HETATM 8557 O O    . HOH E 3 .   ? -5.626  6.696   27.801  1     22.336 ? 916 HOH A O    1 ? 
HETATM 8558 O O    . HOH E 3 .   ? 22.776  18.994  8.79    1     22.138 ? 917 HOH A O    1 ? 
HETATM 8559 O O    . HOH E 3 .   ? -7.035  22.528  4.731   1     36.324 ? 918 HOH A O    1 ? 
HETATM 8560 O O    . HOH E 3 .   ? 18.896  -13.84  26.153  1     36.864 ? 919 HOH A O    1 ? 
HETATM 8561 O O    . HOH E 3 .   ? -9.139  -9.875  18.513  1     53.744 ? 920 HOH A O    1 ? 
HETATM 8562 O O    . HOH E 3 .   ? 10.53   13.532  -3.642  1     32.065 ? 921 HOH A O    1 ? 
HETATM 8563 O O    . HOH E 3 .   ? -1.083  -6.778  26.818  1     32.259 ? 922 HOH A O    1 ? 
HETATM 8564 O O    . HOH E 3 .   ? -6.368  -3.608  12.082  1     43.068 ? 923 HOH A O    1 ? 
HETATM 8565 O O    . HOH E 3 .   ? 27.989  18.773  22.076  1     31.713 ? 924 HOH A O    1 ? 
HETATM 8566 O O    . HOH E 3 .   ? -2.233  -20.668 10.097  1     40.871 ? 925 HOH A O    1 ? 
HETATM 8567 O O    . HOH E 3 .   ? 6.268   -5.232  32.455  1     21.073 ? 926 HOH A O    1 ? 
HETATM 8568 O O    . HOH E 3 .   ? 3.591   -11.175 24.591  1     27.739 ? 927 HOH A O    1 ? 
HETATM 8569 O O    . HOH E 3 .   ? 20.438  -20.675 19.624  1     49.839 ? 928 HOH A O    1 ? 
HETATM 8570 O O    . HOH E 3 .   ? 20.061  -16.594 22.399  1     53.143 ? 929 HOH A O    1 ? 
HETATM 8571 O O    . HOH E 3 .   ? 2.141   -7.028  3.428   1     45.828 ? 930 HOH A O    1 ? 
HETATM 8572 O O    . HOH E 3 .   ? -3.552  15.106  -5.362  1     27.772 ? 931 HOH A O    1 ? 
HETATM 8573 O O    . HOH E 3 .   ? -11.2   -4.798  24.231  1     43.781 ? 932 HOH A O    1 ? 
HETATM 8574 O O    . HOH E 3 .   ? -4.047  -16.532 9.727   1     41.351 ? 933 HOH A O    1 ? 
HETATM 8575 O O    . HOH E 3 .   ? 0.043   -4.047  29.857  1     25.752 ? 934 HOH A O    1 ? 
HETATM 8576 O O    . HOH E 3 .   ? -8.638  -8.925  15.074  1     54.671 ? 935 HOH A O    1 ? 
HETATM 8577 O O    . HOH E 3 .   ? -1.32   25.142  -5.725  1     49.11  ? 936 HOH A O    1 ? 
HETATM 8578 O O    . HOH E 3 .   ? -4.622  16.522  -3.591  1     35.663 ? 937 HOH A O    1 ? 
HETATM 8579 O O    . HOH E 3 .   ? -8.812  -5.917  28.5    1     28.593 ? 938 HOH A O    1 ? 
HETATM 8580 O O    . HOH F 3 .   ? 29.018  57.102  -6.725  0.33  23.089 ? 601 HOH D O    1 ? 
HETATM 8581 O O    . HOH F 3 .   ? 31.923  40.153  7.078   0.33  18.529 ? 602 HOH D O    1 ? 
HETATM 8582 O O    . HOH F 3 .   ? 33.479  40.631  2.227   0.33  20.613 ? 603 HOH D O    1 ? 
HETATM 8583 O O    . HOH F 3 .   ? 13.083  36.999  11.809  0.33  34.27  ? 604 HOH D O    1 ? 
HETATM 8584 O O    . HOH F 3 .   ? 34.074  57.792  -0.204  0.33  11.629 ? 605 HOH D O    1 ? 
HETATM 8585 O O    . HOH F 3 .   ? 34.878  48.124  -13.386 0.33  20.087 ? 606 HOH D O    1 ? 
HETATM 8586 O O    . HOH F 3 .   ? 31.869  38.659  1.518   0.33  22.039 ? 607 HOH D O    1 ? 
HETATM 8587 O O    . HOH F 3 .   ? 37.265  40.826  -6.886  0.33  18.849 ? 608 HOH D O    1 ? 
HETATM 8588 O O    . HOH F 3 .   ? 34.786  34.134  2.224   0.33  18.997 ? 609 HOH D O    1 ? 
HETATM 8589 O O    . HOH F 3 .   ? 12.747  57.853  3.405   0.33  48.443 ? 610 HOH D O    1 ? 
HETATM 8590 O O    . HOH F 3 .   ? 35.243  32.745  -2.317  0.33  26.18  ? 611 HOH D O    1 ? 
HETATM 8591 O O    . HOH F 3 .   ? 33.234  42.554  4.818   0.33  16.573 ? 612 HOH D O    1 ? 
HETATM 8592 O O    . HOH F 3 .   ? 22.313  66.897  -16.390 1     40.238 ? 613 HOH D O    1 ? 
HETATM 8593 O O    . HOH F 3 .   ? 15.656  21.843  -19.668 1     43.613 ? 614 HOH D O    1 ? 
HETATM 8594 O O    . HOH F 3 .   ? 17.278  20.353  1.573   0.33  22.778 ? 615 HOH D O    1 ? 
HETATM 8595 O O    . HOH F 3 .   ? 16.523  41.452  14.677  0.33  15.914 ? 616 HOH D O    1 ? 
HETATM 8596 O O    . HOH F 3 .   ? 35.107  52.088  7.261   0.33  29.887 ? 617 HOH D O    1 ? 
HETATM 8597 O O    . HOH F 3 .   ? 15.302  23.23   4.563   1     22.508 ? 618 HOH D O    1 ? 
HETATM 8598 O O    . HOH F 3 .   ? 12.649  16.484  -1.136  1     37.724 ? 619 HOH D O    1 ? 
HETATM 8599 O O    . HOH F 3 .   ? 30.233  46.332  -2.927  0.33  31.84  ? 620 HOH D O    1 ? 
HETATM 8600 O O    . HOH F 3 .   ? 22.317  22.807  6.036   0.33  18.45  ? 621 HOH D O    1 ? 
HETATM 8601 O O    . HOH F 3 .   ? 12.945  55.996  5.643   0.33  35.047 ? 622 HOH D O    1 ? 
HETATM 8602 O O    . HOH F 3 .   ? 31.918  59.591  -7.089  0.33  12.399 ? 623 HOH D O    1 ? 
HETATM 8603 O O    . HOH F 3 .   ? 32.794  55.552  -8.321  0.33  17.783 ? 624 HOH D O    1 ? 
HETATM 8604 O O    . HOH F 3 .   ? 12.855  18.219  -13.010 1     34.647 ? 625 HOH D O    1 ? 
HETATM 8605 O O    . HOH F 3 .   ? 30.632  40.201  -0.296  0.33  25.123 ? 626 HOH D O    1 ? 
HETATM 8606 O O    . HOH F 3 .   ? 19.246  42.847  -19.055 0.33  16.607 ? 627 HOH D O    1 ? 
HETATM 8607 O O    . HOH F 3 .   ? 24.451  44.846  -14.276 0.33  17.323 ? 628 HOH D O    1 ? 
HETATM 8608 O O    . HOH F 3 .   ? 11.920  38.861  13.499  0.33  24.583 ? 629 HOH D O    1 ? 
HETATM 8609 O O    . HOH F 3 .   ? 20.385  39.593  -19.719 0.33  24.555 ? 630 HOH D O    1 ? 
HETATM 8610 O O    . HOH F 3 .   ? 20.965  29.636  7.254   0.33  22.328 ? 631 HOH D O    1 ? 
HETATM 8611 O O    . HOH F 3 .   ? 21.517  60.827  -13.14  0.33  22.893 ? 632 HOH D O    1 ? 
HETATM 8612 O O    . HOH F 3 .   ? 18.306  66.387  -9.688  1     48.227 ? 633 HOH D O    1 ? 
HETATM 8613 O O    . HOH F 3 .   ? 6.845   24.753  -4.992  1     34.113 ? 634 HOH D O    1 ? 
HETATM 8614 O O    . HOH F 3 .   ? 17.108  54.655  6.587   0.33  16.19  ? 635 HOH D O    1 ? 
HETATM 8615 O O    . HOH F 3 .   ? 14.225  18.519  -0.548  1     47.418 ? 636 HOH D O    1 ? 
HETATM 8616 O O    . HOH F 3 .   ? 26.119  23.663  12.638  1     41.431 ? 637 HOH D O    1 ? 
HETATM 8617 O O    . HOH F 3 .   ? 32.343  31.69   -13.437 0.33  15.429 ? 638 HOH D O    1 ? 
HETATM 8618 O O    . HOH F 3 .   ? 18.105  66.126  -4.200  1     35.566 ? 639 HOH D O    1 ? 
HETATM 8619 O O    . HOH F 3 .   ? 14.699  37.36   -13.597 0.33  23.378 ? 640 HOH D O    1 ? 
HETATM 8620 O O    . HOH F 3 .   ? 13.649  26.085  -1.709  0.33  15.412 ? 641 HOH D O    1 ? 
HETATM 8621 O O    . HOH F 3 .   ? 16.952  56.078  -26.423 0.33  25.711 ? 642 HOH D O    1 ? 
HETATM 8622 O O    . HOH F 3 .   ? 8.924   30.948  -6.86   0.33  15.45  ? 643 HOH D O    1 ? 
HETATM 8623 O O    . HOH F 3 .   ? 20.293  17.94   -9.035  0.33  12.972 ? 644 HOH D O    1 ? 
HETATM 8624 O O    . HOH F 3 .   ? 11.405  37.919  -7.016  0.33  23.84  ? 645 HOH D O    1 ? 
HETATM 8625 O O    . HOH F 3 .   ? 23.756  29.2    1.621   0.33  16.004 ? 646 HOH D O    1 ? 
HETATM 8626 O O    . HOH F 3 .   ? 18.654  59.941  -13.009 0.33  11.853 ? 647 HOH D O    1 ? 
HETATM 8627 O O    . HOH F 3 .   ? 12.956  52.332  -30.434 0.33  37.183 ? 648 HOH D O    1 ? 
HETATM 8628 O O    . HOH F 3 .   ? 20.653  37.416  -6.433  0.33  14.415 ? 649 HOH D O    1 ? 
HETATM 8629 O O    . HOH F 3 .   ? 27.602  49.402  -6.402  0.33  20.958 ? 650 HOH D O    1 ? 
HETATM 8630 O O    . HOH F 3 .   ? 20.428  24.625  12.592  1     30.45  ? 651 HOH D O    1 ? 
HETATM 8631 O O    . HOH F 3 .   ? 28.385  26.265  -13.308 0.33  16.998 ? 652 HOH D O    1 ? 
HETATM 8632 O O    . HOH F 3 .   ? 26.813  29.239  -14.421 0.33  19.954 ? 653 HOH D O    1 ? 
HETATM 8633 O O    . HOH F 3 .   ? 32.269  50.348  -6.497  0.33  34.133 ? 654 HOH D O    1 ? 
HETATM 8634 O O    . HOH F 3 .   ? 22.635  31.424  0.422   0.33  9.655  ? 655 HOH D O    1 ? 
HETATM 8635 O O    . HOH F 3 .   ? 20.62   32.744  -10.816 0.33  11.661 ? 656 HOH D O    1 ? 
HETATM 8636 O O    . HOH F 3 .   ? 14.071  21.088  -1.98   1     41.328 ? 657 HOH D O    1 ? 
HETATM 8637 O O    . HOH F 3 .   ? 31.973  32.994  5.388   0.33  28.996 ? 658 HOH D O    1 ? 
HETATM 8638 O O    . HOH F 3 .   ? 9.470   16.601  -8.954  1     34.137 ? 659 HOH D O    1 ? 
HETATM 8639 O O    . HOH F 3 .   ? 22.09   58.058  -16.703 0.33  17.946 ? 660 HOH D O    1 ? 
HETATM 8640 O O    . HOH F 3 .   ? 13.625  49.637  -0.227  0.33  12.98  ? 661 HOH D O    1 ? 
HETATM 8641 O O    . HOH F 3 .   ? 25.522  29.607  -1.076  0.33  16.574 ? 662 HOH D O    1 ? 
HETATM 8642 O O    . HOH F 3 .   ? 16.912  44.33   13.915  0.33  15.926 ? 663 HOH D O    1 ? 
HETATM 8643 O O    . HOH F 3 .   ? 33.234  46.766  -17.301 0.33  17.393 ? 664 HOH D O    1 ? 
HETATM 8644 O O    . HOH F 3 .   ? 21.177  62.133  -15.434 0.33  27.222 ? 665 HOH D O    1 ? 
HETATM 8645 O O    . HOH F 3 .   ? 8.629   26.954  -8.062  0.33  20.304 ? 666 HOH D O    1 ? 
HETATM 8646 O O    . HOH F 3 .   ? 30.692  30.189  -3.528  0.33  23.539 ? 667 HOH D O    1 ? 
HETATM 8647 O O    . HOH F 3 .   ? 28.325  58.149  -13.985 0.33  15.665 ? 668 HOH D O    1 ? 
HETATM 8648 O O    . HOH F 3 .   ? 26.501  54.735  7.147   0.33  19.457 ? 669 HOH D O    1 ? 
HETATM 8649 O O    . HOH F 3 .   ? 29.707  22.798  -7.145  0.33  20.162 ? 670 HOH D O    1 ? 
HETATM 8650 O O    . HOH F 3 .   ? 30.934  35.073  -6.029  0.33  16.398 ? 671 HOH D O    1 ? 
HETATM 8651 O O    . HOH F 3 .   ? 17.444  44.554  -13.052 0.33  13.232 ? 672 HOH D O    1 ? 
HETATM 8652 O O    . HOH F 3 .   ? 30.98   54.208  -21.162 0.33  29.553 ? 673 HOH D O    1 ? 
HETATM 8653 O O    . HOH F 3 .   ? 13.611  16.357  -6.91   0.33  24.576 ? 674 HOH D O    1 ? 
HETATM 8654 O O    . HOH F 3 .   ? 30.24   48.383  4.085   0.33  14.494 ? 675 HOH D O    1 ? 
HETATM 8655 O O    . HOH F 3 .   ? 21.235  30.333  -7.011  0.33  12.141 ? 676 HOH D O    1 ? 
HETATM 8656 O O    . HOH F 3 .   ? 26.906  52.864  5.281   0.33  25.881 ? 677 HOH D O    1 ? 
HETATM 8657 O O    . HOH F 3 .   ? 31.587  55.31   -9.871  0.33  22.365 ? 678 HOH D O    1 ? 
HETATM 8658 O O    . HOH F 3 .   ? 17.924  25.085  11.181  1     29.549 ? 679 HOH D O    1 ? 
HETATM 8659 O O    . HOH F 3 .   ? 28.359  54.187  -19.304 0.33  20.161 ? 680 HOH D O    1 ? 
HETATM 8660 O O    . HOH F 3 .   ? 22.437  59.729  5.058   0.33  15.071 ? 681 HOH D O    1 ? 
HETATM 8661 O O    . HOH F 3 .   ? 36.227  39.551  -16.895 0.33  22.762 ? 682 HOH D O    1 ? 
HETATM 8662 O O    . HOH F 3 .   ? 15.032  22.858  -0.176  0.33  17.772 ? 683 HOH D O    1 ? 
HETATM 8663 O O    . HOH F 3 .   ? 10.473  28.52   -4.675  0.33  16.927 ? 684 HOH D O    1 ? 
HETATM 8664 O O    . HOH F 3 .   ? 9.026   20.928  -5.163  1     40.018 ? 685 HOH D O    1 ? 
HETATM 8665 O O    . HOH F 3 .   ? 20.511  20.169  8.058   1     24.332 ? 686 HOH D O    1 ? 
HETATM 8666 O O    . HOH F 3 .   ? 23.647  38.701  -20.446 0.33  15.658 ? 687 HOH D O    1 ? 
HETATM 8667 O O    . HOH F 3 .   ? 15.268  50.815  -2.793  0.33  33.136 ? 688 HOH D O    1 ? 
HETATM 8668 O O    . HOH F 3 .   ? 19.603  40.055  -17.078 0.33  20.599 ? 689 HOH D O    1 ? 
HETATM 8669 O O    . HOH F 3 .   ? 18.644  24.833  -15.882 0.33  26.848 ? 690 HOH D O    1 ? 
HETATM 8670 O O    . HOH F 3 .   ? 7.062   42.094  -7.258  0.33  30.384 ? 691 HOH D O    1 ? 
HETATM 8671 O O    . HOH F 3 .   ? 15.607  42.791  -12.42  0.33  15.91  ? 692 HOH D O    1 ? 
HETATM 8672 O O    . HOH F 3 .   ? 12.757  38.582  10.352  0.33  17.171 ? 693 HOH D O    1 ? 
HETATM 8673 O O    . HOH F 3 .   ? 18.287  19.423  -2.745  0.33  20.331 ? 694 HOH D O    1 ? 
HETATM 8674 O O    . HOH F 3 .   ? 28.732  29.154  -1.387  0.33  21.658 ? 695 HOH D O    1 ? 
HETATM 8675 O O    . HOH F 3 .   ? 11.843  37.854  -9.776  0.33  17.17  ? 696 HOH D O    1 ? 
HETATM 8676 O O    . HOH F 3 .   ? 28.79   30.682  -15.608 0.33  18.382 ? 697 HOH D O    1 ? 
HETATM 8677 O O    . HOH F 3 .   ? 10.476  28.789  0.703   0.33  20.092 ? 698 HOH D O    1 ? 
HETATM 8678 O O    . HOH F 3 .   ? 34.461  33.273  -13.623 0.33  28.168 ? 699 HOH D O    1 ? 
HETATM 8679 O O    . HOH F 3 .   ? 15.501  51.642  1.857   0.33  23.449 ? 700 HOH D O    1 ? 
HETATM 8680 O O    . HOH F 3 .   ? 16.179  63.296  -2.115  0.33  24.311 ? 701 HOH D O    1 ? 
HETATM 8681 O O    . HOH F 3 .   ? 16.559  60.289  2.575   0.33  28.105 ? 702 HOH D O    1 ? 
HETATM 8682 O O    . HOH F 3 .   ? 23.916  45.781  -23.744 0.33  28.271 ? 703 HOH D O    1 ? 
HETATM 8683 O O    . HOH F 3 .   ? 25.941  25.541  15.888  1     50.147 ? 704 HOH D O    1 ? 
HETATM 8684 O O    . HOH F 3 .   ? 15.812  46.213  -28.742 0.33  25.842 ? 705 HOH D O    1 ? 
HETATM 8685 O O    . HOH F 3 .   ? 24.874  50.051  -4.334  0.33  19.668 ? 706 HOH D O    1 ? 
HETATM 8686 O O    . HOH F 3 .   ? 28.867  28.897  -18.042 0.33  32.263 ? 707 HOH D O    1 ? 
HETATM 8687 O O    . HOH F 3 .   ? 30.683  50.036  5.508   0.33  21.697 ? 708 HOH D O    1 ? 
HETATM 8688 O O    . HOH F 3 .   ? 15.637  57.611  -31.823 0.33  30.305 ? 709 HOH D O    1 ? 
HETATM 8689 O O    . HOH F 3 .   ? 24.478  59.341  -22.502 0.33  26.767 ? 710 HOH D O    1 ? 
HETATM 8690 O O    . HOH F 3 .   ? 33.852  31.230  2.194   0.33  30.784 ? 711 HOH D O    1 ? 
HETATM 8691 O O    . HOH F 3 .   ? 31.891  58.069  -11.938 0.33  32.018 ? 712 HOH D O    1 ? 
HETATM 8692 O O    . HOH F 3 .   ? 8.957   35.528  15.696  0.33  26.503 ? 713 HOH D O    1 ? 
HETATM 8693 O O    . HOH F 3 .   ? 23.408  58.899  -14.304 0.33  14.916 ? 714 HOH D O    1 ? 
HETATM 8694 O O    . HOH F 3 .   ? 25.283  60.095  -14.373 0.33  24.669 ? 715 HOH D O    1 ? 
HETATM 8695 O O    . HOH F 3 .   ? 18.966  29.605  9.12    0.33  27.662 ? 716 HOH D O    1 ? 
HETATM 8696 O O    . HOH F 3 .   ? 25.232  58.038  -20.618 0.33  19.443 ? 717 HOH D O    1 ? 
HETATM 8697 O O    . HOH F 3 .   ? 11.026  36.414  14.286  0.33  22.675 ? 718 HOH D O    1 ? 
HETATM 8698 O O    . HOH F 3 .   ? 28.196  22.03   -11.666 0.33  18.874 ? 719 HOH D O    1 ? 
HETATM 8699 O O    . HOH F 3 .   ? 25.7    46.306  -23.503 0.33  29.378 ? 720 HOH D O    1 ? 
HETATM 8700 O O    . HOH F 3 .   ? 20.566  61.115  5.862   0.33  30.62  ? 721 HOH D O    1 ? 
HETATM 8701 O O    . HOH F 3 .   ? 22.978  17.335  -12.565 1     38.427 ? 722 HOH D O    1 ? 
HETATM 8702 O O    . HOH F 3 .   ? 8.470   36.326  18.240  0.33  28.622 ? 723 HOH D O    1 ? 
HETATM 8703 O O    . HOH F 3 .   ? 2.202   64.693  -18.649 1     41.995 ? 724 HOH D O    1 ? 
HETATM 8704 O O    . HOH F 3 .   ? 24.343  59.08   -19.071 0.33  26.623 ? 725 HOH D O    1 ? 
HETATM 8705 O O    . HOH F 3 .   ? 24.551  20.891  8.123   1     40.187 ? 726 HOH D O    1 ? 
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