data_9EOB
# 
_entry.id   9EOB 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EOB         pdb_00009eob 10.2210/pdb9eob/pdb 
WWPDB D_1292137303 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-26 ? 
2 'Structure model' 1 1 2025-05-21 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.country'              
2 2 'Structure model' '_citation.journal_abbrev'       
3 2 'Structure model' '_citation.journal_id_CSD'       
4 2 'Structure model' '_citation.journal_id_ISSN'      
5 2 'Structure model' '_citation.pdbx_database_id_DOI' 
6 2 'Structure model' '_citation.year'                 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EOB 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-14 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 maha@bio.dtu.dk Maher         'Abou Hachem' ? 'principal investigator/group leader' 0000-0001-8250-1842 
3 premo@dtu.dk    'Jens Preben' Morth         ? 'principal investigator/group leader' 0000-0003-4077-0192 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Pichler, M.J.'   1 ? 
'Banerjee, S.'    2 ? 
'Nielsen, T.S.'   3 ? 
'Morth, J.P.'     4 ? 
'Abou Hachem, M.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Catalysis' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2155-5435 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Engineered GH181 sialidase from Akkermansia muciniphila' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscatal.5c01023 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Pichler, M.J.'   1 ? 
primary 'Corbella, M.'    2 ? 
primary 'Banerjee, S.'    3 ? 
primary 'Nielsen, T.S.'   4 ? 
primary 'Morth, J.P.'     5 ? 
primary 'Rovira, C.'      6 ? 
primary 'Abou Hachem, M.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man exo-alpha-sialidase     64915.113 1   3.2.1.18 ? ? ? 
2 non-polymer syn 'NICKEL (II) ION'       58.693    1   ?        ? ? ? 
3 non-polymer syn 1,2-ETHANEDIOL          62.068    18  ?        ? ? ? 
4 non-polymer syn 'DI(HYDROXYETHYL)ETHER' 106.120   1   ?        ? ? ? 
5 non-polymer syn 'CHLORIDE ION'          35.453    8   ?        ? ? ? 
6 water       nat water                   18.015    566 ?        ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;PVPEPEVVATPPADAGRGLIRVDSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTRE
FIRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKGRRVIVPFHNMGGGTKFHISD
DGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVLEMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGT
LTMNTLGRLDDGTIVSLWTNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATLDGP
EDRGKAYSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQWTIHTYIPQKKGHCSYNRKPSAELV
QDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGATWNFPNGTTGLVKFRFRVVDGEQADDSGLQVSLTDRLFNACDSTT
KDYALFTFPIRLKPAPHLLLGMKKVPFTPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGASYIHFISTGSQPDA
GILLDTVNARVKLEHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;PVPEPEVVATPPADAGRGLIRVDSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTRE
FIRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKGRRVIVPFHNMGGGTKFHISD
DGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVLEMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGT
LTMNTLGRLDDGTIVSLWTNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATLDGP
EDRGKAYSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQWTIHTYIPQKKGHCSYNRKPSAELV
QDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGATWNFPNGTTGLVKFRFRVVDGEQADDSGLQVSLTDRLFNACDSTT
KDYALFTFPIRLKPAPHLLLGMKKVPFTPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGASYIHFISTGSQPDA
GILLDTVNARVKLEHHHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'NICKEL (II) ION'       NI  
3 1,2-ETHANEDIOL          EDO 
4 'DI(HYDROXYETHYL)ETHER' PEG 
5 'CHLORIDE ION'          CL  
6 water                   HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PRO n 
1 2   VAL n 
1 3   PRO n 
1 4   GLU n 
1 5   PRO n 
1 6   GLU n 
1 7   VAL n 
1 8   VAL n 
1 9   ALA n 
1 10  THR n 
1 11  PRO n 
1 12  PRO n 
1 13  ALA n 
1 14  ASP n 
1 15  ALA n 
1 16  GLY n 
1 17  ARG n 
1 18  GLY n 
1 19  LEU n 
1 20  ILE n 
1 21  ARG n 
1 22  VAL n 
1 23  ASP n 
1 24  SER n 
1 25  ARG n 
1 26  GLU n 
1 27  ILE n 
1 28  ARG n 
1 29  HIS n 
1 30  TYR n 
1 31  SER n 
1 32  GLY n 
1 33  THR n 
1 34  ARG n 
1 35  LYS n 
1 36  GLU n 
1 37  PRO n 
1 38  ASP n 
1 39  TYR n 
1 40  LEU n 
1 41  VAL n 
1 42  SER n 
1 43  ARG n 
1 44  ASP n 
1 45  ASN n 
1 46  GLY n 
1 47  LYS n 
1 48  THR n 
1 49  TRP n 
1 50  GLU n 
1 51  MET n 
1 52  LYS n 
1 53  ALA n 
1 54  ALA n 
1 55  PRO n 
1 56  ALA n 
1 57  GLY n 
1 58  TYR n 
1 59  PRO n 
1 60  PRO n 
1 61  ASN n 
1 62  TYR n 
1 63  GLY n 
1 64  GLY n 
1 65  ILE n 
1 66  PRO n 
1 67  LYS n 
1 68  GLU n 
1 69  SER n 
1 70  PRO n 
1 71  ALA n 
1 72  ILE n 
1 73  VAL n 
1 74  ARG n 
1 75  ASN n 
1 76  PRO n 
1 77  LEU n 
1 78  THR n 
1 79  ARG n 
1 80  GLU n 
1 81  PHE n 
1 82  ILE n 
1 83  ARG n 
1 84  VAL n 
1 85  GLN n 
1 86  PRO n 
1 87  ILE n 
1 88  GLY n 
1 89  GLY n 
1 90  PHE n 
1 91  VAL n 
1 92  PHE n 
1 93  LEU n 
1 94  SER n 
1 95  ARG n 
1 96  GLY n 
1 97  GLY n 
1 98  LEU n 
1 99  ASP n 
1 100 GLY n 
1 101 LYS n 
1 102 TRP n 
1 103 LEU n 
1 104 ALA n 
1 105 VAL n 
1 106 THR n 
1 107 ASN n 
1 108 ASP n 
1 109 GLY n 
1 110 LYS n 
1 111 LEU n 
1 112 GLU n 
1 113 GLU n 
1 114 ASP n 
1 115 TRP n 
1 116 LYS n 
1 117 ASP n 
1 118 PRO n 
1 119 GLU n 
1 120 LYS n 
1 121 ARG n 
1 122 LYS n 
1 123 ASN n 
1 124 LEU n 
1 125 LYS n 
1 126 LYS n 
1 127 LEU n 
1 128 GLY n 
1 129 GLY n 
1 130 ILE n 
1 131 MET n 
1 132 ARG n 
1 133 THR n 
1 134 PRO n 
1 135 VAL n 
1 136 PHE n 
1 137 VAL n 
1 138 ASN n 
1 139 LYS n 
1 140 GLY n 
1 141 ARG n 
1 142 ARG n 
1 143 VAL n 
1 144 ILE n 
1 145 VAL n 
1 146 PRO n 
1 147 PHE n 
1 148 HIS n 
1 149 ASN n 
1 150 MET n 
1 151 GLY n 
1 152 GLY n 
1 153 GLY n 
1 154 THR n 
1 155 LYS n 
1 156 PHE n 
1 157 HIS n 
1 158 ILE n 
1 159 SER n 
1 160 ASP n 
1 161 ASP n 
1 162 GLY n 
1 163 GLY n 
1 164 LEU n 
1 165 THR n 
1 166 TRP n 
1 167 HIS n 
1 168 VAL n 
1 169 SER n 
1 170 ARG n 
1 171 ASN n 
1 172 GLY n 
1 173 VAL n 
1 174 THR n 
1 175 SER n 
1 176 PRO n 
1 177 ARG n 
1 178 HIS n 
1 179 GLU n 
1 180 ALA n 
1 181 ARG n 
1 182 PRO n 
1 183 PRO n 
1 184 HIS n 
1 185 GLN n 
1 186 GLY n 
1 187 VAL n 
1 188 ARG n 
1 189 TRP n 
1 190 PHE n 
1 191 ASN n 
1 192 ASN n 
1 193 ALA n 
1 194 VAL n 
1 195 GLU n 
1 196 ALA n 
1 197 THR n 
1 198 VAL n 
1 199 LEU n 
1 200 GLU n 
1 201 MET n 
1 202 LYS n 
1 203 ASP n 
1 204 GLY n 
1 205 THR n 
1 206 LEU n 
1 207 TRP n 
1 208 ALA n 
1 209 LEU n 
1 210 ALA n 
1 211 ARG n 
1 212 THR n 
1 213 SER n 
1 214 GLN n 
1 215 ASP n 
1 216 GLN n 
1 217 ALA n 
1 218 TRP n 
1 219 GLN n 
1 220 ALA n 
1 221 PHE n 
1 222 SER n 
1 223 LYS n 
1 224 ASP n 
1 225 TYR n 
1 226 GLY n 
1 227 GLU n 
1 228 THR n 
1 229 TRP n 
1 230 SER n 
1 231 LYS n 
1 232 PRO n 
1 233 GLU n 
1 234 PRO n 
1 235 SER n 
1 236 ARG n 
1 237 PHE n 
1 238 PHE n 
1 239 GLY n 
1 240 THR n 
1 241 LEU n 
1 242 THR n 
1 243 MET n 
1 244 ASN n 
1 245 THR n 
1 246 LEU n 
1 247 GLY n 
1 248 ARG n 
1 249 LEU n 
1 250 ASP n 
1 251 ASP n 
1 252 GLY n 
1 253 THR n 
1 254 ILE n 
1 255 VAL n 
1 256 SER n 
1 257 LEU n 
1 258 TRP n 
1 259 THR n 
1 260 ASN n 
1 261 THR n 
1 262 MET n 
1 263 ALA n 
1 264 LEU n 
1 265 PRO n 
1 266 GLU n 
1 267 ASN n 
1 268 ALA n 
1 269 THR n 
1 270 ALA n 
1 271 GLY n 
1 272 ASN n 
1 273 GLY n 
1 274 THR n 
1 275 TRP n 
1 276 GLU n 
1 277 ASP n 
1 278 VAL n 
1 279 PHE n 
1 280 THR n 
1 281 ASN n 
1 282 ARG n 
1 283 ASP n 
1 284 SER n 
1 285 HIS n 
1 286 HIS n 
1 287 ILE n 
1 288 ALA n 
1 289 MET n 
1 290 SER n 
1 291 GLY n 
1 292 ASP n 
1 293 GLU n 
1 294 GLY n 
1 295 LYS n 
1 296 THR n 
1 297 TRP n 
1 298 TYR n 
1 299 GLY n 
1 300 PHE n 
1 301 ARG n 
1 302 GLU n 
1 303 ILE n 
1 304 ILE n 
1 305 LEU n 
1 306 ASP n 
1 307 GLU n 
1 308 HIS n 
1 309 ARG n 
1 310 ASN n 
1 311 HIS n 
1 312 PRO n 
1 313 GLY n 
1 314 TYR n 
1 315 ALA n 
1 316 THR n 
1 317 LEU n 
1 318 ASP n 
1 319 GLY n 
1 320 PRO n 
1 321 GLU n 
1 322 ASP n 
1 323 ARG n 
1 324 GLY n 
1 325 LYS n 
1 326 ALA n 
1 327 TYR n 
1 328 SER n 
1 329 GLU n 
1 330 MET n 
1 331 VAL n 
1 332 GLN n 
1 333 LEU n 
1 334 ASP n 
1 335 LYS n 
1 336 ASN n 
1 337 ARG n 
1 338 ILE n 
1 339 LEU n 
1 340 ILE n 
1 341 SER n 
1 342 LEU n 
1 343 GLY n 
1 344 GLN n 
1 345 HIS n 
1 346 LYS n 
1 347 ASN n 
1 348 HIS n 
1 349 ARG n 
1 350 ARG n 
1 351 LEU n 
1 352 VAL n 
1 353 ILE n 
1 354 VAL n 
1 355 ASP n 
1 356 ARG n 
1 357 ARG n 
1 358 TRP n 
1 359 VAL n 
1 360 GLY n 
1 361 ALA n 
1 362 LYS n 
1 363 THR n 
1 364 ARG n 
1 365 ALA n 
1 366 THR n 
1 367 GLN n 
1 368 THR n 
1 369 GLY n 
1 370 LYS n 
1 371 ASP n 
1 372 LEU n 
1 373 ASP n 
1 374 SER n 
1 375 GLN n 
1 376 TRP n 
1 377 THR n 
1 378 ILE n 
1 379 HIS n 
1 380 THR n 
1 381 TYR n 
1 382 ILE n 
1 383 PRO n 
1 384 GLN n 
1 385 LYS n 
1 386 LYS n 
1 387 GLY n 
1 388 HIS n 
1 389 CYS n 
1 390 SER n 
1 391 TYR n 
1 392 ASN n 
1 393 ARG n 
1 394 LYS n 
1 395 PRO n 
1 396 SER n 
1 397 ALA n 
1 398 GLU n 
1 399 LEU n 
1 400 VAL n 
1 401 GLN n 
1 402 ASP n 
1 403 PRO n 
1 404 SER n 
1 405 GLY n 
1 406 GLY n 
1 407 THR n 
1 408 LYS n 
1 409 LYS n 
1 410 VAL n 
1 411 LEU n 
1 412 GLN n 
1 413 ILE n 
1 414 LYS n 
1 415 ARG n 
1 416 LEU n 
1 417 ASP n 
1 418 ASP n 
1 419 PRO n 
1 420 GLU n 
1 421 LEU n 
1 422 VAL n 
1 423 ASN n 
1 424 GLU n 
1 425 LYS n 
1 426 SER n 
1 427 ASN n 
1 428 VAL n 
1 429 ASP n 
1 430 TYR n 
1 431 ARG n 
1 432 ASN n 
1 433 GLY n 
1 434 GLY n 
1 435 ALA n 
1 436 THR n 
1 437 TRP n 
1 438 ASN n 
1 439 PHE n 
1 440 PRO n 
1 441 ASN n 
1 442 GLY n 
1 443 THR n 
1 444 THR n 
1 445 GLY n 
1 446 LEU n 
1 447 VAL n 
1 448 LYS n 
1 449 PHE n 
1 450 ARG n 
1 451 PHE n 
1 452 ARG n 
1 453 VAL n 
1 454 VAL n 
1 455 ASP n 
1 456 GLY n 
1 457 GLU n 
1 458 GLN n 
1 459 ALA n 
1 460 ASP n 
1 461 ASP n 
1 462 SER n 
1 463 GLY n 
1 464 LEU n 
1 465 GLN n 
1 466 VAL n 
1 467 SER n 
1 468 LEU n 
1 469 THR n 
1 470 ASP n 
1 471 ARG n 
1 472 LEU n 
1 473 PHE n 
1 474 ASN n 
1 475 ALA n 
1 476 CYS n 
1 477 ASP n 
1 478 SER n 
1 479 THR n 
1 480 THR n 
1 481 LYS n 
1 482 ASP n 
1 483 TYR n 
1 484 ALA n 
1 485 LEU n 
1 486 PHE n 
1 487 THR n 
1 488 PHE n 
1 489 PRO n 
1 490 ILE n 
1 491 ARG n 
1 492 LEU n 
1 493 LYS n 
1 494 PRO n 
1 495 ALA n 
1 496 PRO n 
1 497 HIS n 
1 498 LEU n 
1 499 LEU n 
1 500 LEU n 
1 501 GLY n 
1 502 MET n 
1 503 LYS n 
1 504 LYS n 
1 505 VAL n 
1 506 PRO n 
1 507 PHE n 
1 508 THR n 
1 509 PRO n 
1 510 GLY n 
1 511 ALA n 
1 512 TRP n 
1 513 HIS n 
1 514 GLU n 
1 515 ILE n 
1 516 SER n 
1 517 LEU n 
1 518 LEU n 
1 519 TRP n 
1 520 GLN n 
1 521 GLY n 
1 522 GLY n 
1 523 GLN n 
1 524 ALA n 
1 525 VAL n 
1 526 VAL n 
1 527 SER n 
1 528 LEU n 
1 529 ASP n 
1 530 GLY n 
1 531 LYS n 
1 532 LYS n 
1 533 ALA n 
1 534 GLY n 
1 535 THR n 
1 536 LEU n 
1 537 LYS n 
1 538 MET n 
1 539 ALA n 
1 540 ASN n 
1 541 LYS n 
1 542 SER n 
1 543 PRO n 
1 544 ASN n 
1 545 GLY n 
1 546 ALA n 
1 547 SER n 
1 548 TYR n 
1 549 ILE n 
1 550 HIS n 
1 551 PHE n 
1 552 ILE n 
1 553 SER n 
1 554 THR n 
1 555 GLY n 
1 556 SER n 
1 557 GLN n 
1 558 PRO n 
1 559 ASP n 
1 560 ALA n 
1 561 GLY n 
1 562 ILE n 
1 563 LEU n 
1 564 LEU n 
1 565 ASP n 
1 566 THR n 
1 567 VAL n 
1 568 ASN n 
1 569 ALA n 
1 570 ARG n 
1 571 VAL n 
1 572 LYS n 
1 573 LEU n 
1 574 GLU n 
1 575 HIS n 
1 576 HIS n 
1 577 HIS n 
1 578 HIS n 
1 579 HIS n 
1 580 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   580 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 HXS70_08015 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Akkermansia muciniphila ATCC BAA-835' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     349741 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                 ?                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                ?                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE              ?                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'         ?                 'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'          ?                 'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE                ?                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL          'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE               ?                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'         ?                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                 ?                 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE               ?                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                   ?                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE              ?                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                 ?                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                  ?                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE              ?                 'C5 H11 N O2 S'  149.211 
NI  non-polymer         . 'NICKEL (II) ION'       ?                 'Ni 2'           58.693  
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER' ?                 'C4 H10 O3'      106.120 
PHE 'L-peptide linking' y PHENYLALANINE           ?                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                 ?                 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                  ?                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE               ?                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN              ?                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                ?                 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                  ?                 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PRO 1   24  ?   ?   ?   A . n 
A 1 2   VAL 2   25  25  VAL VAL A . n 
A 1 3   PRO 3   26  26  PRO PRO A . n 
A 1 4   GLU 4   27  27  GLU GLU A . n 
A 1 5   PRO 5   28  28  PRO PRO A . n 
A 1 6   GLU 6   29  29  GLU GLU A . n 
A 1 7   VAL 7   30  30  VAL VAL A . n 
A 1 8   VAL 8   31  31  VAL VAL A . n 
A 1 9   ALA 9   32  32  ALA ALA A . n 
A 1 10  THR 10  33  33  THR THR A . n 
A 1 11  PRO 11  34  34  PRO PRO A . n 
A 1 12  PRO 12  35  35  PRO PRO A . n 
A 1 13  ALA 13  36  36  ALA ALA A . n 
A 1 14  ASP 14  37  37  ASP ASP A . n 
A 1 15  ALA 15  38  38  ALA ALA A . n 
A 1 16  GLY 16  39  39  GLY GLY A . n 
A 1 17  ARG 17  40  40  ARG ARG A . n 
A 1 18  GLY 18  41  41  GLY GLY A . n 
A 1 19  LEU 19  42  42  LEU LEU A . n 
A 1 20  ILE 20  43  43  ILE ILE A . n 
A 1 21  ARG 21  44  44  ARG ARG A . n 
A 1 22  VAL 22  45  45  VAL VAL A . n 
A 1 23  ASP 23  46  46  ASP ASP A . n 
A 1 24  SER 24  47  47  SER SER A . n 
A 1 25  ARG 25  48  48  ARG ARG A . n 
A 1 26  GLU 26  49  49  GLU GLU A . n 
A 1 27  ILE 27  50  50  ILE ILE A . n 
A 1 28  ARG 28  51  51  ARG ARG A . n 
A 1 29  HIS 29  52  52  HIS HIS A . n 
A 1 30  TYR 30  53  53  TYR TYR A . n 
A 1 31  SER 31  54  54  SER SER A . n 
A 1 32  GLY 32  55  55  GLY GLY A . n 
A 1 33  THR 33  56  56  THR THR A . n 
A 1 34  ARG 34  57  57  ARG ARG A . n 
A 1 35  LYS 35  58  58  LYS LYS A . n 
A 1 36  GLU 36  59  59  GLU GLU A . n 
A 1 37  PRO 37  60  60  PRO PRO A . n 
A 1 38  ASP 38  61  61  ASP ASP A . n 
A 1 39  TYR 39  62  62  TYR TYR A . n 
A 1 40  LEU 40  63  63  LEU LEU A . n 
A 1 41  VAL 41  64  64  VAL VAL A . n 
A 1 42  SER 42  65  65  SER SER A . n 
A 1 43  ARG 43  66  66  ARG ARG A . n 
A 1 44  ASP 44  67  67  ASP ASP A . n 
A 1 45  ASN 45  68  68  ASN ASN A . n 
A 1 46  GLY 46  69  69  GLY GLY A . n 
A 1 47  LYS 47  70  70  LYS LYS A . n 
A 1 48  THR 48  71  71  THR THR A . n 
A 1 49  TRP 49  72  72  TRP TRP A . n 
A 1 50  GLU 50  73  73  GLU GLU A . n 
A 1 51  MET 51  74  74  MET MET A . n 
A 1 52  LYS 52  75  75  LYS LYS A . n 
A 1 53  ALA 53  76  76  ALA ALA A . n 
A 1 54  ALA 54  77  77  ALA ALA A . n 
A 1 55  PRO 55  78  78  PRO PRO A . n 
A 1 56  ALA 56  79  79  ALA ALA A . n 
A 1 57  GLY 57  80  80  GLY GLY A . n 
A 1 58  TYR 58  81  81  TYR TYR A . n 
A 1 59  PRO 59  82  82  PRO PRO A . n 
A 1 60  PRO 60  83  83  PRO PRO A . n 
A 1 61  ASN 61  84  84  ASN ASN A . n 
A 1 62  TYR 62  85  85  TYR TYR A . n 
A 1 63  GLY 63  86  86  GLY GLY A . n 
A 1 64  GLY 64  87  87  GLY GLY A . n 
A 1 65  ILE 65  88  88  ILE ILE A . n 
A 1 66  PRO 66  89  89  PRO PRO A . n 
A 1 67  LYS 67  90  90  LYS LYS A . n 
A 1 68  GLU 68  91  91  GLU GLU A . n 
A 1 69  SER 69  92  92  SER SER A . n 
A 1 70  PRO 70  93  93  PRO PRO A . n 
A 1 71  ALA 71  94  94  ALA ALA A . n 
A 1 72  ILE 72  95  95  ILE ILE A . n 
A 1 73  VAL 73  96  96  VAL VAL A . n 
A 1 74  ARG 74  97  97  ARG ARG A . n 
A 1 75  ASN 75  98  98  ASN ASN A . n 
A 1 76  PRO 76  99  99  PRO PRO A . n 
A 1 77  LEU 77  100 100 LEU LEU A . n 
A 1 78  THR 78  101 101 THR THR A . n 
A 1 79  ARG 79  102 102 ARG ARG A . n 
A 1 80  GLU 80  103 103 GLU GLU A . n 
A 1 81  PHE 81  104 104 PHE PHE A . n 
A 1 82  ILE 82  105 105 ILE ILE A . n 
A 1 83  ARG 83  106 106 ARG ARG A . n 
A 1 84  VAL 84  107 107 VAL VAL A . n 
A 1 85  GLN 85  108 108 GLN GLN A . n 
A 1 86  PRO 86  109 109 PRO PRO A . n 
A 1 87  ILE 87  110 110 ILE ILE A . n 
A 1 88  GLY 88  111 111 GLY GLY A . n 
A 1 89  GLY 89  112 112 GLY GLY A . n 
A 1 90  PHE 90  113 113 PHE PHE A . n 
A 1 91  VAL 91  114 114 VAL VAL A . n 
A 1 92  PHE 92  115 115 PHE PHE A . n 
A 1 93  LEU 93  116 116 LEU LEU A . n 
A 1 94  SER 94  117 117 SER SER A . n 
A 1 95  ARG 95  118 118 ARG ARG A . n 
A 1 96  GLY 96  119 119 GLY GLY A . n 
A 1 97  GLY 97  120 120 GLY GLY A . n 
A 1 98  LEU 98  121 121 LEU LEU A . n 
A 1 99  ASP 99  122 122 ASP ASP A . n 
A 1 100 GLY 100 123 123 GLY GLY A . n 
A 1 101 LYS 101 124 124 LYS LYS A . n 
A 1 102 TRP 102 125 125 TRP TRP A . n 
A 1 103 LEU 103 126 126 LEU LEU A . n 
A 1 104 ALA 104 127 127 ALA ALA A . n 
A 1 105 VAL 105 128 128 VAL VAL A . n 
A 1 106 THR 106 129 129 THR THR A . n 
A 1 107 ASN 107 130 130 ASN ASN A . n 
A 1 108 ASP 108 131 131 ASP ASP A . n 
A 1 109 GLY 109 132 132 GLY GLY A . n 
A 1 110 LYS 110 133 133 LYS LYS A . n 
A 1 111 LEU 111 134 134 LEU LEU A . n 
A 1 112 GLU 112 135 135 GLU GLU A . n 
A 1 113 GLU 113 136 136 GLU GLU A . n 
A 1 114 ASP 114 137 137 ASP ASP A . n 
A 1 115 TRP 115 138 138 TRP TRP A . n 
A 1 116 LYS 116 139 139 LYS LYS A . n 
A 1 117 ASP 117 140 140 ASP ASP A . n 
A 1 118 PRO 118 141 141 PRO PRO A . n 
A 1 119 GLU 119 142 142 GLU GLU A . n 
A 1 120 LYS 120 143 143 LYS LYS A . n 
A 1 121 ARG 121 144 144 ARG ARG A . n 
A 1 122 LYS 122 145 145 LYS LYS A . n 
A 1 123 ASN 123 146 146 ASN ASN A . n 
A 1 124 LEU 124 147 147 LEU LEU A . n 
A 1 125 LYS 125 148 148 LYS LYS A . n 
A 1 126 LYS 126 149 149 LYS LYS A . n 
A 1 127 LEU 127 150 150 LEU LEU A . n 
A 1 128 GLY 128 151 151 GLY GLY A . n 
A 1 129 GLY 129 152 152 GLY GLY A . n 
A 1 130 ILE 130 153 153 ILE ILE A . n 
A 1 131 MET 131 154 154 MET MET A . n 
A 1 132 ARG 132 155 155 ARG ARG A . n 
A 1 133 THR 133 156 156 THR THR A . n 
A 1 134 PRO 134 157 157 PRO PRO A . n 
A 1 135 VAL 135 158 158 VAL VAL A . n 
A 1 136 PHE 136 159 159 PHE PHE A . n 
A 1 137 VAL 137 160 160 VAL VAL A . n 
A 1 138 ASN 138 161 161 ASN ASN A . n 
A 1 139 LYS 139 162 162 LYS LYS A . n 
A 1 140 GLY 140 163 163 GLY GLY A . n 
A 1 141 ARG 141 164 164 ARG ARG A . n 
A 1 142 ARG 142 165 165 ARG ARG A . n 
A 1 143 VAL 143 166 166 VAL VAL A . n 
A 1 144 ILE 144 167 167 ILE ILE A . n 
A 1 145 VAL 145 168 168 VAL VAL A . n 
A 1 146 PRO 146 169 169 PRO PRO A . n 
A 1 147 PHE 147 170 170 PHE PHE A . n 
A 1 148 HIS 148 171 171 HIS HIS A . n 
A 1 149 ASN 149 172 172 ASN ASN A . n 
A 1 150 MET 150 173 173 MET MET A . n 
A 1 151 GLY 151 174 174 GLY GLY A . n 
A 1 152 GLY 152 175 175 GLY GLY A . n 
A 1 153 GLY 153 176 176 GLY GLY A . n 
A 1 154 THR 154 177 177 THR THR A . n 
A 1 155 LYS 155 178 178 LYS LYS A . n 
A 1 156 PHE 156 179 179 PHE PHE A . n 
A 1 157 HIS 157 180 180 HIS HIS A . n 
A 1 158 ILE 158 181 181 ILE ILE A . n 
A 1 159 SER 159 182 182 SER SER A . n 
A 1 160 ASP 160 183 183 ASP ASP A . n 
A 1 161 ASP 161 184 184 ASP ASP A . n 
A 1 162 GLY 162 185 185 GLY GLY A . n 
A 1 163 GLY 163 186 186 GLY GLY A . n 
A 1 164 LEU 164 187 187 LEU LEU A . n 
A 1 165 THR 165 188 188 THR THR A . n 
A 1 166 TRP 166 189 189 TRP TRP A . n 
A 1 167 HIS 167 190 190 HIS HIS A . n 
A 1 168 VAL 168 191 191 VAL VAL A . n 
A 1 169 SER 169 192 192 SER SER A . n 
A 1 170 ARG 170 193 193 ARG ARG A . n 
A 1 171 ASN 171 194 194 ASN ASN A . n 
A 1 172 GLY 172 195 195 GLY GLY A . n 
A 1 173 VAL 173 196 196 VAL VAL A . n 
A 1 174 THR 174 197 197 THR THR A . n 
A 1 175 SER 175 198 198 SER SER A . n 
A 1 176 PRO 176 199 199 PRO PRO A . n 
A 1 177 ARG 177 200 200 ARG ARG A . n 
A 1 178 HIS 178 201 201 HIS HIS A . n 
A 1 179 GLU 179 202 202 GLU GLU A . n 
A 1 180 ALA 180 203 203 ALA ALA A . n 
A 1 181 ARG 181 204 204 ARG ARG A . n 
A 1 182 PRO 182 205 205 PRO PRO A . n 
A 1 183 PRO 183 206 206 PRO PRO A . n 
A 1 184 HIS 184 207 207 HIS HIS A . n 
A 1 185 GLN 185 208 208 GLN GLN A . n 
A 1 186 GLY 186 209 209 GLY GLY A . n 
A 1 187 VAL 187 210 210 VAL VAL A . n 
A 1 188 ARG 188 211 211 ARG ARG A . n 
A 1 189 TRP 189 212 212 TRP TRP A . n 
A 1 190 PHE 190 213 213 PHE PHE A . n 
A 1 191 ASN 191 214 214 ASN ASN A . n 
A 1 192 ASN 192 215 215 ASN ASN A . n 
A 1 193 ALA 193 216 216 ALA ALA A . n 
A 1 194 VAL 194 217 217 VAL VAL A . n 
A 1 195 GLU 195 218 218 GLU GLU A . n 
A 1 196 ALA 196 219 219 ALA ALA A . n 
A 1 197 THR 197 220 220 THR THR A . n 
A 1 198 VAL 198 221 221 VAL VAL A . n 
A 1 199 LEU 199 222 222 LEU LEU A . n 
A 1 200 GLU 200 223 223 GLU GLU A . n 
A 1 201 MET 201 224 224 MET MET A . n 
A 1 202 LYS 202 225 225 LYS LYS A . n 
A 1 203 ASP 203 226 226 ASP ASP A . n 
A 1 204 GLY 204 227 227 GLY GLY A . n 
A 1 205 THR 205 228 228 THR THR A . n 
A 1 206 LEU 206 229 229 LEU LEU A . n 
A 1 207 TRP 207 230 230 TRP TRP A . n 
A 1 208 ALA 208 231 231 ALA ALA A . n 
A 1 209 LEU 209 232 232 LEU LEU A . n 
A 1 210 ALA 210 233 233 ALA ALA A . n 
A 1 211 ARG 211 234 234 ARG ARG A . n 
A 1 212 THR 212 235 235 THR THR A . n 
A 1 213 SER 213 236 236 SER SER A . n 
A 1 214 GLN 214 237 237 GLN GLN A . n 
A 1 215 ASP 215 238 238 ASP ASP A . n 
A 1 216 GLN 216 239 239 GLN GLN A . n 
A 1 217 ALA 217 240 240 ALA ALA A . n 
A 1 218 TRP 218 241 241 TRP TRP A . n 
A 1 219 GLN 219 242 242 GLN GLN A . n 
A 1 220 ALA 220 243 243 ALA ALA A . n 
A 1 221 PHE 221 244 244 PHE PHE A . n 
A 1 222 SER 222 245 245 SER SER A . n 
A 1 223 LYS 223 246 246 LYS LYS A . n 
A 1 224 ASP 224 247 247 ASP ASP A . n 
A 1 225 TYR 225 248 248 TYR TYR A . n 
A 1 226 GLY 226 249 249 GLY GLY A . n 
A 1 227 GLU 227 250 250 GLU GLU A . n 
A 1 228 THR 228 251 251 THR THR A . n 
A 1 229 TRP 229 252 252 TRP TRP A . n 
A 1 230 SER 230 253 253 SER SER A . n 
A 1 231 LYS 231 254 254 LYS LYS A . n 
A 1 232 PRO 232 255 255 PRO PRO A . n 
A 1 233 GLU 233 256 256 GLU GLU A . n 
A 1 234 PRO 234 257 257 PRO PRO A . n 
A 1 235 SER 235 258 258 SER SER A . n 
A 1 236 ARG 236 259 259 ARG ARG A . n 
A 1 237 PHE 237 260 260 PHE PHE A . n 
A 1 238 PHE 238 261 261 PHE PHE A . n 
A 1 239 GLY 239 262 262 GLY GLY A . n 
A 1 240 THR 240 263 263 THR THR A . n 
A 1 241 LEU 241 264 264 LEU LEU A . n 
A 1 242 THR 242 265 265 THR THR A . n 
A 1 243 MET 243 266 266 MET MET A . n 
A 1 244 ASN 244 267 267 ASN ASN A . n 
A 1 245 THR 245 268 268 THR THR A . n 
A 1 246 LEU 246 269 269 LEU LEU A . n 
A 1 247 GLY 247 270 270 GLY GLY A . n 
A 1 248 ARG 248 271 271 ARG ARG A . n 
A 1 249 LEU 249 272 272 LEU LEU A . n 
A 1 250 ASP 250 273 273 ASP ASP A . n 
A 1 251 ASP 251 274 274 ASP ASP A . n 
A 1 252 GLY 252 275 275 GLY GLY A . n 
A 1 253 THR 253 276 276 THR THR A . n 
A 1 254 ILE 254 277 277 ILE ILE A . n 
A 1 255 VAL 255 278 278 VAL VAL A . n 
A 1 256 SER 256 279 279 SER SER A . n 
A 1 257 LEU 257 280 280 LEU LEU A . n 
A 1 258 TRP 258 281 281 TRP TRP A . n 
A 1 259 THR 259 282 282 THR THR A . n 
A 1 260 ASN 260 283 283 ASN ASN A . n 
A 1 261 THR 261 284 284 THR THR A . n 
A 1 262 MET 262 285 285 MET MET A . n 
A 1 263 ALA 263 286 286 ALA ALA A . n 
A 1 264 LEU 264 287 287 LEU LEU A . n 
A 1 265 PRO 265 288 288 PRO PRO A . n 
A 1 266 GLU 266 289 289 GLU GLU A . n 
A 1 267 ASN 267 290 290 ASN ASN A . n 
A 1 268 ALA 268 291 291 ALA ALA A . n 
A 1 269 THR 269 292 292 THR THR A . n 
A 1 270 ALA 270 293 293 ALA ALA A . n 
A 1 271 GLY 271 294 294 GLY GLY A . n 
A 1 272 ASN 272 295 295 ASN ASN A . n 
A 1 273 GLY 273 296 296 GLY GLY A . n 
A 1 274 THR 274 297 297 THR THR A . n 
A 1 275 TRP 275 298 298 TRP TRP A . n 
A 1 276 GLU 276 299 299 GLU GLU A . n 
A 1 277 ASP 277 300 300 ASP ASP A . n 
A 1 278 VAL 278 301 301 VAL VAL A . n 
A 1 279 PHE 279 302 302 PHE PHE A . n 
A 1 280 THR 280 303 303 THR THR A . n 
A 1 281 ASN 281 304 304 ASN ASN A . n 
A 1 282 ARG 282 305 305 ARG ARG A . n 
A 1 283 ASP 283 306 306 ASP ASP A . n 
A 1 284 SER 284 307 307 SER SER A . n 
A 1 285 HIS 285 308 308 HIS HIS A . n 
A 1 286 HIS 286 309 309 HIS HIS A . n 
A 1 287 ILE 287 310 310 ILE ILE A . n 
A 1 288 ALA 288 311 311 ALA ALA A . n 
A 1 289 MET 289 312 312 MET MET A . n 
A 1 290 SER 290 313 313 SER SER A . n 
A 1 291 GLY 291 314 314 GLY GLY A . n 
A 1 292 ASP 292 315 315 ASP ASP A . n 
A 1 293 GLU 293 316 316 GLU GLU A . n 
A 1 294 GLY 294 317 317 GLY GLY A . n 
A 1 295 LYS 295 318 318 LYS LYS A . n 
A 1 296 THR 296 319 319 THR THR A . n 
A 1 297 TRP 297 320 320 TRP TRP A . n 
A 1 298 TYR 298 321 321 TYR TYR A . n 
A 1 299 GLY 299 322 322 GLY GLY A . n 
A 1 300 PHE 300 323 323 PHE PHE A . n 
A 1 301 ARG 301 324 324 ARG ARG A . n 
A 1 302 GLU 302 325 325 GLU GLU A . n 
A 1 303 ILE 303 326 326 ILE ILE A . n 
A 1 304 ILE 304 327 327 ILE ILE A . n 
A 1 305 LEU 305 328 328 LEU LEU A . n 
A 1 306 ASP 306 329 329 ASP ASP A . n 
A 1 307 GLU 307 330 330 GLU GLU A . n 
A 1 308 HIS 308 331 331 HIS HIS A . n 
A 1 309 ARG 309 332 332 ARG ARG A . n 
A 1 310 ASN 310 333 333 ASN ASN A . n 
A 1 311 HIS 311 334 334 HIS HIS A . n 
A 1 312 PRO 312 335 335 PRO PRO A . n 
A 1 313 GLY 313 336 336 GLY GLY A . n 
A 1 314 TYR 314 337 337 TYR TYR A . n 
A 1 315 ALA 315 338 338 ALA ALA A . n 
A 1 316 THR 316 339 339 THR THR A . n 
A 1 317 LEU 317 340 340 LEU LEU A . n 
A 1 318 ASP 318 341 341 ASP ASP A . n 
A 1 319 GLY 319 342 342 GLY GLY A . n 
A 1 320 PRO 320 343 343 PRO PRO A . n 
A 1 321 GLU 321 344 344 GLU GLU A . n 
A 1 322 ASP 322 345 345 ASP ASP A . n 
A 1 323 ARG 323 346 346 ARG ARG A . n 
A 1 324 GLY 324 347 347 GLY GLY A . n 
A 1 325 LYS 325 348 348 LYS LYS A . n 
A 1 326 ALA 326 349 349 ALA ALA A . n 
A 1 327 TYR 327 350 350 TYR TYR A . n 
A 1 328 SER 328 351 351 SER SER A . n 
A 1 329 GLU 329 352 352 GLU GLU A . n 
A 1 330 MET 330 353 353 MET MET A . n 
A 1 331 VAL 331 354 354 VAL VAL A . n 
A 1 332 GLN 332 355 355 GLN GLN A . n 
A 1 333 LEU 333 356 356 LEU LEU A . n 
A 1 334 ASP 334 357 357 ASP ASP A . n 
A 1 335 LYS 335 358 358 LYS LYS A . n 
A 1 336 ASN 336 359 359 ASN ASN A . n 
A 1 337 ARG 337 360 360 ARG ARG A . n 
A 1 338 ILE 338 361 361 ILE ILE A . n 
A 1 339 LEU 339 362 362 LEU LEU A . n 
A 1 340 ILE 340 363 363 ILE ILE A . n 
A 1 341 SER 341 364 364 SER SER A . n 
A 1 342 LEU 342 365 365 LEU LEU A . n 
A 1 343 GLY 343 366 366 GLY GLY A . n 
A 1 344 GLN 344 367 367 GLN GLN A . n 
A 1 345 HIS 345 368 368 HIS HIS A . n 
A 1 346 LYS 346 369 369 LYS LYS A . n 
A 1 347 ASN 347 370 370 ASN ASN A . n 
A 1 348 HIS 348 371 371 HIS HIS A . n 
A 1 349 ARG 349 372 372 ARG ARG A . n 
A 1 350 ARG 350 373 373 ARG ARG A . n 
A 1 351 LEU 351 374 374 LEU LEU A . n 
A 1 352 VAL 352 375 375 VAL VAL A . n 
A 1 353 ILE 353 376 376 ILE ILE A . n 
A 1 354 VAL 354 377 377 VAL VAL A . n 
A 1 355 ASP 355 378 378 ASP ASP A . n 
A 1 356 ARG 356 379 379 ARG ARG A . n 
A 1 357 ARG 357 380 380 ARG ARG A . n 
A 1 358 TRP 358 381 381 TRP TRP A . n 
A 1 359 VAL 359 382 382 VAL VAL A . n 
A 1 360 GLY 360 383 383 GLY GLY A . n 
A 1 361 ALA 361 384 384 ALA ALA A . n 
A 1 362 LYS 362 385 385 LYS LYS A . n 
A 1 363 THR 363 386 386 THR THR A . n 
A 1 364 ARG 364 387 387 ARG ARG A . n 
A 1 365 ALA 365 388 388 ALA ALA A . n 
A 1 366 THR 366 389 389 THR THR A . n 
A 1 367 GLN 367 390 390 GLN GLN A . n 
A 1 368 THR 368 391 391 THR THR A . n 
A 1 369 GLY 369 392 392 GLY GLY A . n 
A 1 370 LYS 370 393 393 LYS LYS A . n 
A 1 371 ASP 371 394 394 ASP ASP A . n 
A 1 372 LEU 372 395 395 LEU LEU A . n 
A 1 373 ASP 373 396 396 ASP ASP A . n 
A 1 374 SER 374 397 397 SER SER A . n 
A 1 375 GLN 375 398 398 GLN GLN A . n 
A 1 376 TRP 376 399 399 TRP TRP A . n 
A 1 377 THR 377 400 400 THR THR A . n 
A 1 378 ILE 378 401 401 ILE ILE A . n 
A 1 379 HIS 379 402 402 HIS HIS A . n 
A 1 380 THR 380 403 403 THR THR A . n 
A 1 381 TYR 381 404 404 TYR TYR A . n 
A 1 382 ILE 382 405 405 ILE ILE A . n 
A 1 383 PRO 383 406 406 PRO PRO A . n 
A 1 384 GLN 384 407 407 GLN GLN A . n 
A 1 385 LYS 385 408 408 LYS LYS A . n 
A 1 386 LYS 386 409 409 LYS LYS A . n 
A 1 387 GLY 387 410 410 GLY GLY A . n 
A 1 388 HIS 388 411 411 HIS HIS A . n 
A 1 389 CYS 389 412 412 CYS CYS A . n 
A 1 390 SER 390 413 413 SER SER A . n 
A 1 391 TYR 391 414 414 TYR TYR A . n 
A 1 392 ASN 392 415 415 ASN ASN A . n 
A 1 393 ARG 393 416 416 ARG ARG A . n 
A 1 394 LYS 394 417 417 LYS LYS A . n 
A 1 395 PRO 395 418 418 PRO PRO A . n 
A 1 396 SER 396 419 419 SER SER A . n 
A 1 397 ALA 397 420 420 ALA ALA A . n 
A 1 398 GLU 398 421 421 GLU GLU A . n 
A 1 399 LEU 399 422 422 LEU LEU A . n 
A 1 400 VAL 400 423 423 VAL VAL A . n 
A 1 401 GLN 401 424 424 GLN GLN A . n 
A 1 402 ASP 402 425 425 ASP ASP A . n 
A 1 403 PRO 403 426 426 PRO PRO A . n 
A 1 404 SER 404 427 427 SER SER A . n 
A 1 405 GLY 405 428 428 GLY GLY A . n 
A 1 406 GLY 406 429 429 GLY GLY A . n 
A 1 407 THR 407 430 430 THR THR A . n 
A 1 408 LYS 408 431 431 LYS LYS A . n 
A 1 409 LYS 409 432 432 LYS LYS A . n 
A 1 410 VAL 410 433 433 VAL VAL A . n 
A 1 411 LEU 411 434 434 LEU LEU A . n 
A 1 412 GLN 412 435 435 GLN GLN A . n 
A 1 413 ILE 413 436 436 ILE ILE A . n 
A 1 414 LYS 414 437 437 LYS LYS A . n 
A 1 415 ARG 415 438 438 ARG ARG A . n 
A 1 416 LEU 416 439 439 LEU LEU A . n 
A 1 417 ASP 417 440 440 ASP ASP A . n 
A 1 418 ASP 418 441 441 ASP ASP A . n 
A 1 419 PRO 419 442 442 PRO PRO A . n 
A 1 420 GLU 420 443 443 GLU GLU A . n 
A 1 421 LEU 421 444 444 LEU LEU A . n 
A 1 422 VAL 422 445 445 VAL VAL A . n 
A 1 423 ASN 423 446 446 ASN ASN A . n 
A 1 424 GLU 424 447 447 GLU GLU A . n 
A 1 425 LYS 425 448 448 LYS LYS A . n 
A 1 426 SER 426 449 449 SER SER A . n 
A 1 427 ASN 427 450 450 ASN ASN A . n 
A 1 428 VAL 428 451 451 VAL VAL A . n 
A 1 429 ASP 429 452 452 ASP ASP A . n 
A 1 430 TYR 430 453 453 TYR TYR A . n 
A 1 431 ARG 431 454 454 ARG ARG A . n 
A 1 432 ASN 432 455 455 ASN ASN A . n 
A 1 433 GLY 433 456 456 GLY GLY A . n 
A 1 434 GLY 434 457 457 GLY GLY A . n 
A 1 435 ALA 435 458 458 ALA ALA A . n 
A 1 436 THR 436 459 459 THR THR A . n 
A 1 437 TRP 437 460 460 TRP TRP A . n 
A 1 438 ASN 438 461 461 ASN ASN A . n 
A 1 439 PHE 439 462 462 PHE PHE A . n 
A 1 440 PRO 440 463 463 PRO PRO A . n 
A 1 441 ASN 441 464 464 ASN ASN A . n 
A 1 442 GLY 442 465 465 GLY GLY A . n 
A 1 443 THR 443 466 466 THR THR A . n 
A 1 444 THR 444 467 467 THR THR A . n 
A 1 445 GLY 445 468 468 GLY GLY A . n 
A 1 446 LEU 446 469 469 LEU LEU A . n 
A 1 447 VAL 447 470 470 VAL VAL A . n 
A 1 448 LYS 448 471 471 LYS LYS A . n 
A 1 449 PHE 449 472 472 PHE PHE A . n 
A 1 450 ARG 450 473 473 ARG ARG A . n 
A 1 451 PHE 451 474 474 PHE PHE A . n 
A 1 452 ARG 452 475 475 ARG ARG A . n 
A 1 453 VAL 453 476 476 VAL VAL A . n 
A 1 454 VAL 454 477 477 VAL VAL A . n 
A 1 455 ASP 455 478 478 ASP ASP A . n 
A 1 456 GLY 456 479 479 GLY GLY A . n 
A 1 457 GLU 457 480 480 GLU GLU A . n 
A 1 458 GLN 458 481 481 GLN GLN A . n 
A 1 459 ALA 459 482 482 ALA ALA A . n 
A 1 460 ASP 460 483 483 ASP ASP A . n 
A 1 461 ASP 461 484 484 ASP ASP A . n 
A 1 462 SER 462 485 485 SER SER A . n 
A 1 463 GLY 463 486 486 GLY GLY A . n 
A 1 464 LEU 464 487 487 LEU LEU A . n 
A 1 465 GLN 465 488 488 GLN GLN A . n 
A 1 466 VAL 466 489 489 VAL VAL A . n 
A 1 467 SER 467 490 490 SER SER A . n 
A 1 468 LEU 468 491 491 LEU LEU A . n 
A 1 469 THR 469 492 492 THR THR A . n 
A 1 470 ASP 470 493 493 ASP ASP A . n 
A 1 471 ARG 471 494 494 ARG ARG A . n 
A 1 472 LEU 472 495 495 LEU LEU A . n 
A 1 473 PHE 473 496 496 PHE PHE A . n 
A 1 474 ASN 474 497 497 ASN ASN A . n 
A 1 475 ALA 475 498 498 ALA ALA A . n 
A 1 476 CYS 476 499 499 CYS CYS A . n 
A 1 477 ASP 477 500 500 ASP ASP A . n 
A 1 478 SER 478 501 501 SER SER A . n 
A 1 479 THR 479 502 502 THR THR A . n 
A 1 480 THR 480 503 503 THR THR A . n 
A 1 481 LYS 481 504 504 LYS LYS A . n 
A 1 482 ASP 482 505 505 ASP ASP A . n 
A 1 483 TYR 483 506 506 TYR TYR A . n 
A 1 484 ALA 484 507 507 ALA ALA A . n 
A 1 485 LEU 485 508 508 LEU LEU A . n 
A 1 486 PHE 486 509 509 PHE PHE A . n 
A 1 487 THR 487 510 510 THR THR A . n 
A 1 488 PHE 488 511 511 PHE PHE A . n 
A 1 489 PRO 489 512 512 PRO PRO A . n 
A 1 490 ILE 490 513 513 ILE ILE A . n 
A 1 491 ARG 491 514 514 ARG ARG A . n 
A 1 492 LEU 492 515 515 LEU LEU A . n 
A 1 493 LYS 493 516 516 LYS LYS A . n 
A 1 494 PRO 494 517 517 PRO PRO A . n 
A 1 495 ALA 495 518 518 ALA ALA A . n 
A 1 496 PRO 496 519 519 PRO PRO A . n 
A 1 497 HIS 497 520 520 HIS HIS A . n 
A 1 498 LEU 498 521 521 LEU LEU A . n 
A 1 499 LEU 499 522 522 LEU LEU A . n 
A 1 500 LEU 500 523 523 LEU LEU A . n 
A 1 501 GLY 501 524 524 GLY GLY A . n 
A 1 502 MET 502 525 525 MET MET A . n 
A 1 503 LYS 503 526 526 LYS LYS A . n 
A 1 504 LYS 504 527 527 LYS LYS A . n 
A 1 505 VAL 505 528 528 VAL VAL A . n 
A 1 506 PRO 506 529 529 PRO PRO A . n 
A 1 507 PHE 507 530 530 PHE PHE A . n 
A 1 508 THR 508 531 531 THR THR A . n 
A 1 509 PRO 509 532 532 PRO PRO A . n 
A 1 510 GLY 510 533 533 GLY GLY A . n 
A 1 511 ALA 511 534 534 ALA ALA A . n 
A 1 512 TRP 512 535 535 TRP TRP A . n 
A 1 513 HIS 513 536 536 HIS HIS A . n 
A 1 514 GLU 514 537 537 GLU GLU A . n 
A 1 515 ILE 515 538 538 ILE ILE A . n 
A 1 516 SER 516 539 539 SER SER A . n 
A 1 517 LEU 517 540 540 LEU LEU A . n 
A 1 518 LEU 518 541 541 LEU LEU A . n 
A 1 519 TRP 519 542 542 TRP TRP A . n 
A 1 520 GLN 520 543 543 GLN GLN A . n 
A 1 521 GLY 521 544 544 GLY GLY A . n 
A 1 522 GLY 522 545 545 GLY GLY A . n 
A 1 523 GLN 523 546 546 GLN GLN A . n 
A 1 524 ALA 524 547 547 ALA ALA A . n 
A 1 525 VAL 525 548 548 VAL VAL A . n 
A 1 526 VAL 526 549 549 VAL VAL A . n 
A 1 527 SER 527 550 550 SER SER A . n 
A 1 528 LEU 528 551 551 LEU LEU A . n 
A 1 529 ASP 529 552 552 ASP ASP A . n 
A 1 530 GLY 530 553 553 GLY GLY A . n 
A 1 531 LYS 531 554 554 LYS LYS A . n 
A 1 532 LYS 532 555 555 LYS LYS A . n 
A 1 533 ALA 533 556 556 ALA ALA A . n 
A 1 534 GLY 534 557 557 GLY GLY A . n 
A 1 535 THR 535 558 558 THR THR A . n 
A 1 536 LEU 536 559 559 LEU LEU A . n 
A 1 537 LYS 537 560 560 LYS LYS A . n 
A 1 538 MET 538 561 561 MET MET A . n 
A 1 539 ALA 539 562 562 ALA ALA A . n 
A 1 540 ASN 540 563 563 ASN ASN A . n 
A 1 541 LYS 541 564 564 LYS LYS A . n 
A 1 542 SER 542 565 565 SER SER A . n 
A 1 543 PRO 543 566 566 PRO PRO A . n 
A 1 544 ASN 544 567 567 ASN ASN A . n 
A 1 545 GLY 545 568 568 GLY GLY A . n 
A 1 546 ALA 546 569 569 ALA ALA A . n 
A 1 547 SER 547 570 570 SER SER A . n 
A 1 548 TYR 548 571 571 TYR TYR A . n 
A 1 549 ILE 549 572 572 ILE ILE A . n 
A 1 550 HIS 550 573 573 HIS HIS A . n 
A 1 551 PHE 551 574 574 PHE PHE A . n 
A 1 552 ILE 552 575 575 ILE ILE A . n 
A 1 553 SER 553 576 576 SER SER A . n 
A 1 554 THR 554 577 577 THR THR A . n 
A 1 555 GLY 555 578 578 GLY GLY A . n 
A 1 556 SER 556 579 579 SER SER A . n 
A 1 557 GLN 557 580 580 GLN GLN A . n 
A 1 558 PRO 558 581 581 PRO PRO A . n 
A 1 559 ASP 559 582 582 ASP ASP A . n 
A 1 560 ALA 560 583 583 ALA ALA A . n 
A 1 561 GLY 561 584 584 GLY GLY A . n 
A 1 562 ILE 562 585 585 ILE ILE A . n 
A 1 563 LEU 563 586 586 LEU LEU A . n 
A 1 564 LEU 564 587 587 LEU LEU A . n 
A 1 565 ASP 565 588 588 ASP ASP A . n 
A 1 566 THR 566 589 589 THR THR A . n 
A 1 567 VAL 567 590 590 VAL VAL A . n 
A 1 568 ASN 568 591 591 ASN ASN A . n 
A 1 569 ALA 569 592 592 ALA ALA A . n 
A 1 570 ARG 570 593 593 ARG ARG A . n 
A 1 571 VAL 571 594 594 VAL VAL A . n 
A 1 572 LYS 572 595 595 LYS LYS A . n 
A 1 573 LEU 573 596 596 LEU LEU A . n 
A 1 574 GLU 574 597 597 GLU GLU A . n 
A 1 575 HIS 575 598 598 HIS HIS A . n 
A 1 576 HIS 576 599 599 HIS HIS A . n 
A 1 577 HIS 577 600 600 HIS HIS A . n 
A 1 578 HIS 578 601 601 HIS HIS A . n 
A 1 579 HIS 579 602 602 HIS HIS A . n 
A 1 580 HIS 580 603 603 HIS HIS A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B  2 NI  1   701  701 NI  NI  A . 
C  3 EDO 1   702  801 EDO EDO A . 
D  3 EDO 1   703  802 EDO EDO A . 
E  3 EDO 1   704  803 EDO EDO A . 
F  3 EDO 1   705  804 EDO EDO A . 
G  3 EDO 1   706  805 EDO EDO A . 
H  3 EDO 1   707  806 EDO EDO A . 
I  3 EDO 1   708  809 EDO EDO A . 
J  3 EDO 1   709  810 EDO EDO A . 
K  3 EDO 1   710  811 EDO EDO A . 
L  4 PEG 1   711  812 PEG PEG A . 
M  3 EDO 1   712  813 EDO EDO A . 
N  3 EDO 1   713  814 EDO EDO A . 
O  3 EDO 1   714  815 EDO EDO A . 
P  3 EDO 1   715  816 EDO EDO A . 
Q  3 EDO 1   716  817 EDO EDO A . 
R  3 EDO 1   717  818 EDO EDO A . 
S  3 EDO 1   718  819 EDO EDO A . 
T  3 EDO 1   719  820 EDO EDO A . 
U  3 EDO 1   720  821 EDO EDO A . 
V  5 CL  1   721  1   CL  CL  A . 
W  5 CL  1   722  4   CL  CL  A . 
X  5 CL  1   723  5   CL  CL  A . 
Y  5 CL  1   724  6   CL  CL  A . 
Z  5 CL  1   725  8   CL  CL  A . 
AA 5 CL  1   726  9   CL  CL  A . 
BA 5 CL  1   727  10  CL  CL  A . 
CA 5 CL  1   728  11  CL  CL  A . 
DA 6 HOH 1   801  778 HOH HOH A . 
DA 6 HOH 2   802  898 HOH HOH A . 
DA 6 HOH 3   803  713 HOH HOH A . 
DA 6 HOH 4   804  102 HOH HOH A . 
DA 6 HOH 5   805  678 HOH HOH A . 
DA 6 HOH 6   806  817 HOH HOH A . 
DA 6 HOH 7   807  884 HOH HOH A . 
DA 6 HOH 8   808  294 HOH HOH A . 
DA 6 HOH 9   809  872 HOH HOH A . 
DA 6 HOH 10  810  848 HOH HOH A . 
DA 6 HOH 11  811  288 HOH HOH A . 
DA 6 HOH 12  812  751 HOH HOH A . 
DA 6 HOH 13  813  856 HOH HOH A . 
DA 6 HOH 14  814  234 HOH HOH A . 
DA 6 HOH 15  815  871 HOH HOH A . 
DA 6 HOH 16  816  860 HOH HOH A . 
DA 6 HOH 17  817  627 HOH HOH A . 
DA 6 HOH 18  818  894 HOH HOH A . 
DA 6 HOH 19  819  25  HOH HOH A . 
DA 6 HOH 20  820  626 HOH HOH A . 
DA 6 HOH 21  821  217 HOH HOH A . 
DA 6 HOH 22  822  261 HOH HOH A . 
DA 6 HOH 23  823  846 HOH HOH A . 
DA 6 HOH 24  824  912 HOH HOH A . 
DA 6 HOH 25  825  338 HOH HOH A . 
DA 6 HOH 26  826  193 HOH HOH A . 
DA 6 HOH 27  827  744 HOH HOH A . 
DA 6 HOH 28  828  885 HOH HOH A . 
DA 6 HOH 29  829  797 HOH HOH A . 
DA 6 HOH 30  830  199 HOH HOH A . 
DA 6 HOH 31  831  158 HOH HOH A . 
DA 6 HOH 32  832  867 HOH HOH A . 
DA 6 HOH 33  833  725 HOH HOH A . 
DA 6 HOH 34  834  775 HOH HOH A . 
DA 6 HOH 35  835  831 HOH HOH A . 
DA 6 HOH 36  836  215 HOH HOH A . 
DA 6 HOH 37  837  658 HOH HOH A . 
DA 6 HOH 38  838  877 HOH HOH A . 
DA 6 HOH 39  839  318 HOH HOH A . 
DA 6 HOH 40  840  712 HOH HOH A . 
DA 6 HOH 41  841  630 HOH HOH A . 
DA 6 HOH 42  842  140 HOH HOH A . 
DA 6 HOH 43  843  132 HOH HOH A . 
DA 6 HOH 44  844  676 HOH HOH A . 
DA 6 HOH 45  845  788 HOH HOH A . 
DA 6 HOH 46  846  682 HOH HOH A . 
DA 6 HOH 47  847  796 HOH HOH A . 
DA 6 HOH 48  848  27  HOH HOH A . 
DA 6 HOH 49  849  737 HOH HOH A . 
DA 6 HOH 50  850  864 HOH HOH A . 
DA 6 HOH 51  851  209 HOH HOH A . 
DA 6 HOH 52  852  252 HOH HOH A . 
DA 6 HOH 53  853  114 HOH HOH A . 
DA 6 HOH 54  854  37  HOH HOH A . 
DA 6 HOH 55  855  20  HOH HOH A . 
DA 6 HOH 56  856  107 HOH HOH A . 
DA 6 HOH 57  857  250 HOH HOH A . 
DA 6 HOH 58  858  81  HOH HOH A . 
DA 6 HOH 59  859  823 HOH HOH A . 
DA 6 HOH 60  860  106 HOH HOH A . 
DA 6 HOH 61  861  210 HOH HOH A . 
DA 6 HOH 62  862  638 HOH HOH A . 
DA 6 HOH 63  863  223 HOH HOH A . 
DA 6 HOH 64  864  188 HOH HOH A . 
DA 6 HOH 65  865  843 HOH HOH A . 
DA 6 HOH 66  866  151 HOH HOH A . 
DA 6 HOH 67  867  192 HOH HOH A . 
DA 6 HOH 68  868  310 HOH HOH A . 
DA 6 HOH 69  869  76  HOH HOH A . 
DA 6 HOH 70  870  913 HOH HOH A . 
DA 6 HOH 71  871  110 HOH HOH A . 
DA 6 HOH 72  872  804 HOH HOH A . 
DA 6 HOH 73  873  161 HOH HOH A . 
DA 6 HOH 74  874  24  HOH HOH A . 
DA 6 HOH 75  875  706 HOH HOH A . 
DA 6 HOH 76  876  218 HOH HOH A . 
DA 6 HOH 77  877  667 HOH HOH A . 
DA 6 HOH 78  878  749 HOH HOH A . 
DA 6 HOH 79  879  123 HOH HOH A . 
DA 6 HOH 80  880  821 HOH HOH A . 
DA 6 HOH 81  881  243 HOH HOH A . 
DA 6 HOH 82  882  268 HOH HOH A . 
DA 6 HOH 83  883  264 HOH HOH A . 
DA 6 HOH 84  884  164 HOH HOH A . 
DA 6 HOH 85  885  642 HOH HOH A . 
DA 6 HOH 86  886  731 HOH HOH A . 
DA 6 HOH 87  887  300 HOH HOH A . 
DA 6 HOH 88  888  820 HOH HOH A . 
DA 6 HOH 89  889  9   HOH HOH A . 
DA 6 HOH 90  890  681 HOH HOH A . 
DA 6 HOH 91  891  44  HOH HOH A . 
DA 6 HOH 92  892  5   HOH HOH A . 
DA 6 HOH 93  893  738 HOH HOH A . 
DA 6 HOH 94  894  17  HOH HOH A . 
DA 6 HOH 95  895  722 HOH HOH A . 
DA 6 HOH 96  896  825 HOH HOH A . 
DA 6 HOH 97  897  23  HOH HOH A . 
DA 6 HOH 98  898  75  HOH HOH A . 
DA 6 HOH 99  899  768 HOH HOH A . 
DA 6 HOH 100 900  272 HOH HOH A . 
DA 6 HOH 101 901  202 HOH HOH A . 
DA 6 HOH 102 902  2   HOH HOH A . 
DA 6 HOH 103 903  675 HOH HOH A . 
DA 6 HOH 104 904  753 HOH HOH A . 
DA 6 HOH 105 905  259 HOH HOH A . 
DA 6 HOH 106 906  824 HOH HOH A . 
DA 6 HOH 107 907  904 HOH HOH A . 
DA 6 HOH 108 908  69  HOH HOH A . 
DA 6 HOH 109 909  875 HOH HOH A . 
DA 6 HOH 110 910  97  HOH HOH A . 
DA 6 HOH 111 911  12  HOH HOH A . 
DA 6 HOH 112 912  224 HOH HOH A . 
DA 6 HOH 113 913  52  HOH HOH A . 
DA 6 HOH 114 914  732 HOH HOH A . 
DA 6 HOH 115 915  652 HOH HOH A . 
DA 6 HOH 116 916  648 HOH HOH A . 
DA 6 HOH 117 917  771 HOH HOH A . 
DA 6 HOH 118 918  171 HOH HOH A . 
DA 6 HOH 119 919  808 HOH HOH A . 
DA 6 HOH 120 920  148 HOH HOH A . 
DA 6 HOH 121 921  363 HOH HOH A . 
DA 6 HOH 122 922  93  HOH HOH A . 
DA 6 HOH 123 923  84  HOH HOH A . 
DA 6 HOH 124 924  19  HOH HOH A . 
DA 6 HOH 125 925  80  HOH HOH A . 
DA 6 HOH 126 926  131 HOH HOH A . 
DA 6 HOH 127 927  639 HOH HOH A . 
DA 6 HOH 128 928  70  HOH HOH A . 
DA 6 HOH 129 929  694 HOH HOH A . 
DA 6 HOH 130 930  207 HOH HOH A . 
DA 6 HOH 131 931  679 HOH HOH A . 
DA 6 HOH 132 932  273 HOH HOH A . 
DA 6 HOH 133 933  62  HOH HOH A . 
DA 6 HOH 134 934  47  HOH HOH A . 
DA 6 HOH 135 935  666 HOH HOH A . 
DA 6 HOH 136 936  868 HOH HOH A . 
DA 6 HOH 137 937  137 HOH HOH A . 
DA 6 HOH 138 938  95  HOH HOH A . 
DA 6 HOH 139 939  125 HOH HOH A . 
DA 6 HOH 140 940  690 HOH HOH A . 
DA 6 HOH 141 941  66  HOH HOH A . 
DA 6 HOH 142 942  781 HOH HOH A . 
DA 6 HOH 143 943  765 HOH HOH A . 
DA 6 HOH 144 944  136 HOH HOH A . 
DA 6 HOH 145 945  298 HOH HOH A . 
DA 6 HOH 146 946  798 HOH HOH A . 
DA 6 HOH 147 947  230 HOH HOH A . 
DA 6 HOH 148 948  237 HOH HOH A . 
DA 6 HOH 149 949  349 HOH HOH A . 
DA 6 HOH 150 950  124 HOH HOH A . 
DA 6 HOH 151 951  562 HOH HOH A . 
DA 6 HOH 152 952  82  HOH HOH A . 
DA 6 HOH 153 953  180 HOH HOH A . 
DA 6 HOH 154 954  296 HOH HOH A . 
DA 6 HOH 155 955  635 HOH HOH A . 
DA 6 HOH 156 956  728 HOH HOH A . 
DA 6 HOH 157 957  680 HOH HOH A . 
DA 6 HOH 158 958  145 HOH HOH A . 
DA 6 HOH 159 959  747 HOH HOH A . 
DA 6 HOH 160 960  33  HOH HOH A . 
DA 6 HOH 161 961  108 HOH HOH A . 
DA 6 HOH 162 962  814 HOH HOH A . 
DA 6 HOH 163 963  64  HOH HOH A . 
DA 6 HOH 164 964  695 HOH HOH A . 
DA 6 HOH 165 965  907 HOH HOH A . 
DA 6 HOH 166 966  717 HOH HOH A . 
DA 6 HOH 167 967  688 HOH HOH A . 
DA 6 HOH 168 968  283 HOH HOH A . 
DA 6 HOH 169 969  557 HOH HOH A . 
DA 6 HOH 170 970  748 HOH HOH A . 
DA 6 HOH 171 971  715 HOH HOH A . 
DA 6 HOH 172 972  197 HOH HOH A . 
DA 6 HOH 173 973  201 HOH HOH A . 
DA 6 HOH 174 974  780 HOH HOH A . 
DA 6 HOH 175 975  646 HOH HOH A . 
DA 6 HOH 176 976  135 HOH HOH A . 
DA 6 HOH 177 977  645 HOH HOH A . 
DA 6 HOH 178 978  238 HOH HOH A . 
DA 6 HOH 179 979  116 HOH HOH A . 
DA 6 HOH 180 980  166 HOH HOH A . 
DA 6 HOH 181 981  92  HOH HOH A . 
DA 6 HOH 182 982  56  HOH HOH A . 
DA 6 HOH 183 983  79  HOH HOH A . 
DA 6 HOH 184 984  705 HOH HOH A . 
DA 6 HOH 185 985  130 HOH HOH A . 
DA 6 HOH 186 986  631 HOH HOH A . 
DA 6 HOH 187 987  876 HOH HOH A . 
DA 6 HOH 188 988  13  HOH HOH A . 
DA 6 HOH 189 989  10  HOH HOH A . 
DA 6 HOH 190 990  356 HOH HOH A . 
DA 6 HOH 191 991  229 HOH HOH A . 
DA 6 HOH 192 992  7   HOH HOH A . 
DA 6 HOH 193 993  42  HOH HOH A . 
DA 6 HOH 194 994  214 HOH HOH A . 
DA 6 HOH 195 995  699 HOH HOH A . 
DA 6 HOH 196 996  191 HOH HOH A . 
DA 6 HOH 197 997  785 HOH HOH A . 
DA 6 HOH 198 998  176 HOH HOH A . 
DA 6 HOH 199 999  767 HOH HOH A . 
DA 6 HOH 200 1000 34  HOH HOH A . 
DA 6 HOH 201 1001 54  HOH HOH A . 
DA 6 HOH 202 1002 41  HOH HOH A . 
DA 6 HOH 203 1003 206 HOH HOH A . 
DA 6 HOH 204 1004 236 HOH HOH A . 
DA 6 HOH 205 1005 643 HOH HOH A . 
DA 6 HOH 206 1006 184 HOH HOH A . 
DA 6 HOH 207 1007 128 HOH HOH A . 
DA 6 HOH 208 1008 316 HOH HOH A . 
DA 6 HOH 209 1009 156 HOH HOH A . 
DA 6 HOH 210 1010 73  HOH HOH A . 
DA 6 HOH 211 1011 302 HOH HOH A . 
DA 6 HOH 212 1012 170 HOH HOH A . 
DA 6 HOH 213 1013 36  HOH HOH A . 
DA 6 HOH 214 1014 812 HOH HOH A . 
DA 6 HOH 215 1015 704 HOH HOH A . 
DA 6 HOH 216 1016 889 HOH HOH A . 
DA 6 HOH 217 1017 43  HOH HOH A . 
DA 6 HOH 218 1018 818 HOH HOH A . 
DA 6 HOH 219 1019 126 HOH HOH A . 
DA 6 HOH 220 1020 219 HOH HOH A . 
DA 6 HOH 221 1021 686 HOH HOH A . 
DA 6 HOH 222 1022 144 HOH HOH A . 
DA 6 HOH 223 1023 659 HOH HOH A . 
DA 6 HOH 224 1024 162 HOH HOH A . 
DA 6 HOH 225 1025 697 HOH HOH A . 
DA 6 HOH 226 1026 330 HOH HOH A . 
DA 6 HOH 227 1027 326 HOH HOH A . 
DA 6 HOH 228 1028 159 HOH HOH A . 
DA 6 HOH 229 1029 661 HOH HOH A . 
DA 6 HOH 230 1030 881 HOH HOH A . 
DA 6 HOH 231 1031 59  HOH HOH A . 
DA 6 HOH 232 1032 840 HOH HOH A . 
DA 6 HOH 233 1033 182 HOH HOH A . 
DA 6 HOH 234 1034 651 HOH HOH A . 
DA 6 HOH 235 1035 101 HOH HOH A . 
DA 6 HOH 236 1036 870 HOH HOH A . 
DA 6 HOH 237 1037 723 HOH HOH A . 
DA 6 HOH 238 1038 633 HOH HOH A . 
DA 6 HOH 239 1039 53  HOH HOH A . 
DA 6 HOH 240 1040 32  HOH HOH A . 
DA 6 HOH 241 1041 154 HOH HOH A . 
DA 6 HOH 242 1042 120 HOH HOH A . 
DA 6 HOH 243 1043 248 HOH HOH A . 
DA 6 HOH 244 1044 762 HOH HOH A . 
DA 6 HOH 245 1045 305 HOH HOH A . 
DA 6 HOH 246 1046 693 HOH HOH A . 
DA 6 HOH 247 1047 189 HOH HOH A . 
DA 6 HOH 248 1048 4   HOH HOH A . 
DA 6 HOH 249 1049 168 HOH HOH A . 
DA 6 HOH 250 1050 277 HOH HOH A . 
DA 6 HOH 251 1051 669 HOH HOH A . 
DA 6 HOH 252 1052 644 HOH HOH A . 
DA 6 HOH 253 1053 647 HOH HOH A . 
DA 6 HOH 254 1054 246 HOH HOH A . 
DA 6 HOH 255 1055 65  HOH HOH A . 
DA 6 HOH 256 1056 660 HOH HOH A . 
DA 6 HOH 257 1057 157 HOH HOH A . 
DA 6 HOH 258 1058 134 HOH HOH A . 
DA 6 HOH 259 1059 172 HOH HOH A . 
DA 6 HOH 260 1060 198 HOH HOH A . 
DA 6 HOH 261 1061 782 HOH HOH A . 
DA 6 HOH 262 1062 90  HOH HOH A . 
DA 6 HOH 263 1063 242 HOH HOH A . 
DA 6 HOH 264 1064 708 HOH HOH A . 
DA 6 HOH 265 1065 707 HOH HOH A . 
DA 6 HOH 266 1066 649 HOH HOH A . 
DA 6 HOH 267 1067 35  HOH HOH A . 
DA 6 HOH 268 1068 196 HOH HOH A . 
DA 6 HOH 269 1069 279 HOH HOH A . 
DA 6 HOH 270 1070 670 HOH HOH A . 
DA 6 HOH 271 1071 86  HOH HOH A . 
DA 6 HOH 272 1072 103 HOH HOH A . 
DA 6 HOH 273 1073 181 HOH HOH A . 
DA 6 HOH 274 1074 260 HOH HOH A . 
DA 6 HOH 275 1075 284 HOH HOH A . 
DA 6 HOH 276 1076 822 HOH HOH A . 
DA 6 HOH 277 1077 698 HOH HOH A . 
DA 6 HOH 278 1078 141 HOH HOH A . 
DA 6 HOH 279 1079 175 HOH HOH A . 
DA 6 HOH 280 1080 15  HOH HOH A . 
DA 6 HOH 281 1081 628 HOH HOH A . 
DA 6 HOH 282 1082 850 HOH HOH A . 
DA 6 HOH 283 1083 903 HOH HOH A . 
DA 6 HOH 284 1084 178 HOH HOH A . 
DA 6 HOH 285 1085 656 HOH HOH A . 
DA 6 HOH 286 1086 67  HOH HOH A . 
DA 6 HOH 287 1087 6   HOH HOH A . 
DA 6 HOH 288 1088 61  HOH HOH A . 
DA 6 HOH 289 1089 83  HOH HOH A . 
DA 6 HOH 290 1090 905 HOH HOH A . 
DA 6 HOH 291 1091 634 HOH HOH A . 
DA 6 HOH 292 1092 50  HOH HOH A . 
DA 6 HOH 293 1093 21  HOH HOH A . 
DA 6 HOH 294 1094 740 HOH HOH A . 
DA 6 HOH 295 1095 222 HOH HOH A . 
DA 6 HOH 296 1096 133 HOH HOH A . 
DA 6 HOH 297 1097 89  HOH HOH A . 
DA 6 HOH 298 1098 879 HOH HOH A . 
DA 6 HOH 299 1099 45  HOH HOH A . 
DA 6 HOH 300 1100 26  HOH HOH A . 
DA 6 HOH 301 1101 18  HOH HOH A . 
DA 6 HOH 302 1102 672 HOH HOH A . 
DA 6 HOH 303 1103 221 HOH HOH A . 
DA 6 HOH 304 1104 185 HOH HOH A . 
DA 6 HOH 305 1105 716 HOH HOH A . 
DA 6 HOH 306 1106 799 HOH HOH A . 
DA 6 HOH 307 1107 28  HOH HOH A . 
DA 6 HOH 308 1108 16  HOH HOH A . 
DA 6 HOH 309 1109 851 HOH HOH A . 
DA 6 HOH 310 1110 39  HOH HOH A . 
DA 6 HOH 311 1111 146 HOH HOH A . 
DA 6 HOH 312 1112 3   HOH HOH A . 
DA 6 HOH 313 1113 866 HOH HOH A . 
DA 6 HOH 314 1114 553 HOH HOH A . 
DA 6 HOH 315 1115 581 HOH HOH A . 
DA 6 HOH 316 1116 769 HOH HOH A . 
DA 6 HOH 317 1117 60  HOH HOH A . 
DA 6 HOH 318 1118 325 HOH HOH A . 
DA 6 HOH 319 1119 152 HOH HOH A . 
DA 6 HOH 320 1120 816 HOH HOH A . 
DA 6 HOH 321 1121 700 HOH HOH A . 
DA 6 HOH 322 1122 204 HOH HOH A . 
DA 6 HOH 323 1123 730 HOH HOH A . 
DA 6 HOH 324 1124 119 HOH HOH A . 
DA 6 HOH 325 1125 113 HOH HOH A . 
DA 6 HOH 326 1126 68  HOH HOH A . 
DA 6 HOH 327 1127 869 HOH HOH A . 
DA 6 HOH 328 1128 112 HOH HOH A . 
DA 6 HOH 329 1129 632 HOH HOH A . 
DA 6 HOH 330 1130 203 HOH HOH A . 
DA 6 HOH 331 1131 741 HOH HOH A . 
DA 6 HOH 332 1132 721 HOH HOH A . 
DA 6 HOH 333 1133 63  HOH HOH A . 
DA 6 HOH 334 1134 11  HOH HOH A . 
DA 6 HOH 335 1135 177 HOH HOH A . 
DA 6 HOH 336 1136 228 HOH HOH A . 
DA 6 HOH 337 1137 834 HOH HOH A . 
DA 6 HOH 338 1138 127 HOH HOH A . 
DA 6 HOH 339 1139 1   HOH HOH A . 
DA 6 HOH 340 1140 684 HOH HOH A . 
DA 6 HOH 341 1141 784 HOH HOH A . 
DA 6 HOH 342 1142 629 HOH HOH A . 
DA 6 HOH 343 1143 703 HOH HOH A . 
DA 6 HOH 344 1144 655 HOH HOH A . 
DA 6 HOH 345 1145 48  HOH HOH A . 
DA 6 HOH 346 1146 153 HOH HOH A . 
DA 6 HOH 347 1147 674 HOH HOH A . 
DA 6 HOH 348 1148 803 HOH HOH A . 
DA 6 HOH 349 1149 211 HOH HOH A . 
DA 6 HOH 350 1150 245 HOH HOH A . 
DA 6 HOH 351 1151 637 HOH HOH A . 
DA 6 HOH 352 1152 650 HOH HOH A . 
DA 6 HOH 353 1153 567 HOH HOH A . 
DA 6 HOH 354 1154 71  HOH HOH A . 
DA 6 HOH 355 1155 98  HOH HOH A . 
DA 6 HOH 356 1156 241 HOH HOH A . 
DA 6 HOH 357 1157 720 HOH HOH A . 
DA 6 HOH 358 1158 169 HOH HOH A . 
DA 6 HOH 359 1159 878 HOH HOH A . 
DA 6 HOH 360 1160 220 HOH HOH A . 
DA 6 HOH 361 1161 689 HOH HOH A . 
DA 6 HOH 362 1162 78  HOH HOH A . 
DA 6 HOH 363 1163 226 HOH HOH A . 
DA 6 HOH 364 1164 30  HOH HOH A . 
DA 6 HOH 365 1165 99  HOH HOH A . 
DA 6 HOH 366 1166 696 HOH HOH A . 
DA 6 HOH 367 1167 149 HOH HOH A . 
DA 6 HOH 368 1168 173 HOH HOH A . 
DA 6 HOH 369 1169 244 HOH HOH A . 
DA 6 HOH 370 1170 819 HOH HOH A . 
DA 6 HOH 371 1171 72  HOH HOH A . 
DA 6 HOH 372 1172 121 HOH HOH A . 
DA 6 HOH 373 1173 104 HOH HOH A . 
DA 6 HOH 374 1174 255 HOH HOH A . 
DA 6 HOH 375 1175 143 HOH HOH A . 
DA 6 HOH 376 1176 111 HOH HOH A . 
DA 6 HOH 377 1177 847 HOH HOH A . 
DA 6 HOH 378 1178 759 HOH HOH A . 
DA 6 HOH 379 1179 194 HOH HOH A . 
DA 6 HOH 380 1180 726 HOH HOH A . 
DA 6 HOH 381 1181 854 HOH HOH A . 
DA 6 HOH 382 1182 118 HOH HOH A . 
DA 6 HOH 383 1183 40  HOH HOH A . 
DA 6 HOH 384 1184 208 HOH HOH A . 
DA 6 HOH 385 1185 662 HOH HOH A . 
DA 6 HOH 386 1186 874 HOH HOH A . 
DA 6 HOH 387 1187 586 HOH HOH A . 
DA 6 HOH 388 1188 285 HOH HOH A . 
DA 6 HOH 389 1189 55  HOH HOH A . 
DA 6 HOH 390 1190 138 HOH HOH A . 
DA 6 HOH 391 1191 654 HOH HOH A . 
DA 6 HOH 392 1192 908 HOH HOH A . 
DA 6 HOH 393 1193 551 HOH HOH A . 
DA 6 HOH 394 1194 701 HOH HOH A . 
DA 6 HOH 395 1195 313 HOH HOH A . 
DA 6 HOH 396 1196 886 HOH HOH A . 
DA 6 HOH 397 1197 212 HOH HOH A . 
DA 6 HOH 398 1198 692 HOH HOH A . 
DA 6 HOH 399 1199 46  HOH HOH A . 
DA 6 HOH 400 1200 890 HOH HOH A . 
DA 6 HOH 401 1201 85  HOH HOH A . 
DA 6 HOH 402 1202 887 HOH HOH A . 
DA 6 HOH 403 1203 772 HOH HOH A . 
DA 6 HOH 404 1204 87  HOH HOH A . 
DA 6 HOH 405 1205 58  HOH HOH A . 
DA 6 HOH 406 1206 160 HOH HOH A . 
DA 6 HOH 407 1207 142 HOH HOH A . 
DA 6 HOH 408 1208 94  HOH HOH A . 
DA 6 HOH 409 1209 807 HOH HOH A . 
DA 6 HOH 410 1210 909 HOH HOH A . 
DA 6 HOH 411 1211 105 HOH HOH A . 
DA 6 HOH 412 1212 583 HOH HOH A . 
DA 6 HOH 413 1213 258 HOH HOH A . 
DA 6 HOH 414 1214 758 HOH HOH A . 
DA 6 HOH 415 1215 571 HOH HOH A . 
DA 6 HOH 416 1216 247 HOH HOH A . 
DA 6 HOH 417 1217 251 HOH HOH A . 
DA 6 HOH 418 1218 653 HOH HOH A . 
DA 6 HOH 419 1219 179 HOH HOH A . 
DA 6 HOH 420 1220 691 HOH HOH A . 
DA 6 HOH 421 1221 664 HOH HOH A . 
DA 6 HOH 422 1222 687 HOH HOH A . 
DA 6 HOH 423 1223 826 HOH HOH A . 
DA 6 HOH 424 1224 685 HOH HOH A . 
DA 6 HOH 425 1225 743 HOH HOH A . 
DA 6 HOH 426 1226 752 HOH HOH A . 
DA 6 HOH 427 1227 22  HOH HOH A . 
DA 6 HOH 428 1228 793 HOH HOH A . 
DA 6 HOH 429 1229 773 HOH HOH A . 
DA 6 HOH 430 1230 309 HOH HOH A . 
DA 6 HOH 431 1231 902 HOH HOH A . 
DA 6 HOH 432 1232 14  HOH HOH A . 
DA 6 HOH 433 1233 227 HOH HOH A . 
DA 6 HOH 434 1234 835 HOH HOH A . 
DA 6 HOH 435 1235 736 HOH HOH A . 
DA 6 HOH 436 1236 891 HOH HOH A . 
DA 6 HOH 437 1237 789 HOH HOH A . 
DA 6 HOH 438 1238 746 HOH HOH A . 
DA 6 HOH 439 1239 813 HOH HOH A . 
DA 6 HOH 440 1240 366 HOH HOH A . 
DA 6 HOH 441 1241 640 HOH HOH A . 
DA 6 HOH 442 1242 714 HOH HOH A . 
DA 6 HOH 443 1243 683 HOH HOH A . 
DA 6 HOH 444 1244 718 HOH HOH A . 
DA 6 HOH 445 1245 810 HOH HOH A . 
DA 6 HOH 446 1246 906 HOH HOH A . 
DA 6 HOH 447 1247 559 HOH HOH A . 
DA 6 HOH 448 1248 710 HOH HOH A . 
DA 6 HOH 449 1249 852 HOH HOH A . 
DA 6 HOH 450 1250 549 HOH HOH A . 
DA 6 HOH 451 1251 739 HOH HOH A . 
DA 6 HOH 452 1252 815 HOH HOH A . 
DA 6 HOH 453 1253 745 HOH HOH A . 
DA 6 HOH 454 1254 883 HOH HOH A . 
DA 6 HOH 455 1255 734 HOH HOH A . 
DA 6 HOH 456 1256 361 HOH HOH A . 
DA 6 HOH 457 1257 837 HOH HOH A . 
DA 6 HOH 458 1258 838 HOH HOH A . 
DA 6 HOH 459 1259 842 HOH HOH A . 
DA 6 HOH 460 1260 555 HOH HOH A . 
DA 6 HOH 461 1261 861 HOH HOH A . 
DA 6 HOH 462 1262 205 HOH HOH A . 
DA 6 HOH 463 1263 677 HOH HOH A . 
DA 6 HOH 464 1264 346 HOH HOH A . 
DA 6 HOH 465 1265 117 HOH HOH A . 
DA 6 HOH 466 1266 845 HOH HOH A . 
DA 6 HOH 467 1267 829 HOH HOH A . 
DA 6 HOH 468 1268 900 HOH HOH A . 
DA 6 HOH 469 1269 240 HOH HOH A . 
DA 6 HOH 470 1270 641 HOH HOH A . 
DA 6 HOH 471 1271 787 HOH HOH A . 
DA 6 HOH 472 1272 577 HOH HOH A . 
DA 6 HOH 473 1273 895 HOH HOH A . 
DA 6 HOH 474 1274 863 HOH HOH A . 
DA 6 HOH 475 1275 873 HOH HOH A . 
DA 6 HOH 476 1276 805 HOH HOH A . 
DA 6 HOH 477 1277 836 HOH HOH A . 
DA 6 HOH 478 1278 853 HOH HOH A . 
DA 6 HOH 479 1279 702 HOH HOH A . 
DA 6 HOH 480 1280 795 HOH HOH A . 
DA 6 HOH 481 1281 231 HOH HOH A . 
DA 6 HOH 482 1282 174 HOH HOH A . 
DA 6 HOH 483 1283 839 HOH HOH A . 
DA 6 HOH 484 1284 282 HOH HOH A . 
DA 6 HOH 485 1285 859 HOH HOH A . 
DA 6 HOH 486 1286 892 HOH HOH A . 
DA 6 HOH 487 1287 729 HOH HOH A . 
DA 6 HOH 488 1288 323 HOH HOH A . 
DA 6 HOH 489 1289 147 HOH HOH A . 
DA 6 HOH 490 1290 901 HOH HOH A . 
DA 6 HOH 491 1291 882 HOH HOH A . 
DA 6 HOH 492 1292 51  HOH HOH A . 
DA 6 HOH 493 1293 750 HOH HOH A . 
DA 6 HOH 494 1294 49  HOH HOH A . 
DA 6 HOH 495 1295 914 HOH HOH A . 
DA 6 HOH 496 1296 830 HOH HOH A . 
DA 6 HOH 497 1297 213 HOH HOH A . 
DA 6 HOH 498 1298 91  HOH HOH A . 
DA 6 HOH 499 1299 766 HOH HOH A . 
DA 6 HOH 500 1300 262 HOH HOH A . 
DA 6 HOH 501 1301 663 HOH HOH A . 
DA 6 HOH 502 1302 724 HOH HOH A . 
DA 6 HOH 503 1303 893 HOH HOH A . 
DA 6 HOH 504 1304 911 HOH HOH A . 
DA 6 HOH 505 1305 915 HOH HOH A . 
DA 6 HOH 506 1306 235 HOH HOH A . 
DA 6 HOH 507 1307 657 HOH HOH A . 
DA 6 HOH 508 1308 833 HOH HOH A . 
DA 6 HOH 509 1309 828 HOH HOH A . 
DA 6 HOH 510 1310 865 HOH HOH A . 
DA 6 HOH 511 1311 668 HOH HOH A . 
DA 6 HOH 512 1312 276 HOH HOH A . 
DA 6 HOH 513 1313 74  HOH HOH A . 
DA 6 HOH 514 1314 770 HOH HOH A . 
DA 6 HOH 515 1315 858 HOH HOH A . 
DA 6 HOH 516 1316 585 HOH HOH A . 
DA 6 HOH 517 1317 800 HOH HOH A . 
DA 6 HOH 518 1318 763 HOH HOH A . 
DA 6 HOH 519 1319 801 HOH HOH A . 
DA 6 HOH 520 1320 783 HOH HOH A . 
DA 6 HOH 521 1321 910 HOH HOH A . 
DA 6 HOH 522 1322 333 HOH HOH A . 
DA 6 HOH 523 1323 790 HOH HOH A . 
DA 6 HOH 524 1324 709 HOH HOH A . 
DA 6 HOH 525 1325 190 HOH HOH A . 
DA 6 HOH 526 1326 257 HOH HOH A . 
DA 6 HOH 527 1327 888 HOH HOH A . 
DA 6 HOH 528 1328 155 HOH HOH A . 
DA 6 HOH 529 1329 671 HOH HOH A . 
DA 6 HOH 530 1330 794 HOH HOH A . 
DA 6 HOH 531 1331 880 HOH HOH A . 
DA 6 HOH 532 1332 760 HOH HOH A . 
DA 6 HOH 533 1333 862 HOH HOH A . 
DA 6 HOH 534 1334 122 HOH HOH A . 
DA 6 HOH 535 1335 756 HOH HOH A . 
DA 6 HOH 536 1336 827 HOH HOH A . 
DA 6 HOH 537 1337 100 HOH HOH A . 
DA 6 HOH 538 1338 266 HOH HOH A . 
DA 6 HOH 539 1339 896 HOH HOH A . 
DA 6 HOH 540 1340 857 HOH HOH A . 
DA 6 HOH 541 1341 791 HOH HOH A . 
DA 6 HOH 542 1342 779 HOH HOH A . 
DA 6 HOH 543 1343 186 HOH HOH A . 
DA 6 HOH 544 1344 774 HOH HOH A . 
DA 6 HOH 545 1345 263 HOH HOH A . 
DA 6 HOH 546 1346 764 HOH HOH A . 
DA 6 HOH 547 1347 719 HOH HOH A . 
DA 6 HOH 548 1348 200 HOH HOH A . 
DA 6 HOH 549 1349 832 HOH HOH A . 
DA 6 HOH 550 1350 233 HOH HOH A . 
DA 6 HOH 551 1351 844 HOH HOH A . 
DA 6 HOH 552 1352 167 HOH HOH A . 
DA 6 HOH 553 1353 849 HOH HOH A . 
DA 6 HOH 554 1354 809 HOH HOH A . 
DA 6 HOH 555 1355 755 HOH HOH A . 
DA 6 HOH 556 1356 757 HOH HOH A . 
DA 6 HOH 557 1357 564 HOH HOH A . 
DA 6 HOH 558 1358 761 HOH HOH A . 
DA 6 HOH 559 1359 855 HOH HOH A . 
DA 6 HOH 560 1360 792 HOH HOH A . 
DA 6 HOH 561 1361 777 HOH HOH A . 
DA 6 HOH 562 1362 841 HOH HOH A . 
DA 6 HOH 563 1363 554 HOH HOH A . 
DA 6 HOH 564 1364 899 HOH HOH A . 
DA 6 HOH 565 1365 897 HOH HOH A . 
DA 6 HOH 566 1366 806 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? TRUNCATE ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP   ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EOB 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     74.670 
_cell.length_a_esd                 ? 
_cell.length_b                     88.189 
_cell.length_b_esd                 ? 
_cell.length_c                     99.585 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EOB 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EOB 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.53 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          51.30 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '10% PEG 8000 W/V, 9% Ethylene glycol (v/v), 0.1M HEPES pH 7.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-02-03 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.98 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'MAX IV BEAMLINE BioMAX' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.98 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BioMAX 
_diffrn_source.pdbx_synchrotron_site       'MAX IV' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9EOB 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.77 
_reflns.d_resolution_low                               66.02 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     64414 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                9.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.77 
_reflns_shell.d_res_low                                     1.80 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             6073 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.503 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.045 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            0.647 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -0.692 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               24.106 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.972 
_refine.correlation_coeff_Fo_to_Fc_free          0.954 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9EOB 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.770 
_refine.ls_d_res_low                             66.02 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     64414 
_refine.ls_number_reflns_R_free                  3267 
_refine.ls_number_reflns_R_work                  61147 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.473 
_refine.ls_percent_reflns_R_free                 5.072 
_refine.ls_R_factor_all                          0.157 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1953 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1552 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.102 
_refine.pdbx_overall_ESU_R_Free                  0.104 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             2.430 
_refine.overall_SU_ML                            0.073 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        4572 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         88 
_refine_hist.number_atoms_solvent             566 
_refine_hist.number_atoms_total               5226 
_refine_hist.d_res_high                       1.770 
_refine_hist.d_res_low                        66.02 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.012  4852  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  4563  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.519  1.674  6556  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.515  1.593  10511 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 7.662  5.000  600   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 6.963  5.000  41    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.187 10.000 798   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 17.127 10.000 226   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.074  0.200  684   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.009  0.020  5867  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  1157  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.200  0.200  782   ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200  4288  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.173  0.200  2259  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.087  0.200  2547  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.167  0.200  420   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.149  0.200  5     ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.228  0.200  22    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.182  0.200  63    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.143  0.200  35    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.166  2.372  2370  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.165  2.372  2370  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.992  4.255  2980  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.992  4.255  2981  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 3.386  2.739  2482  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.385  2.740  2483  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 5.063  4.796  3576  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.062  4.798  3577  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 6.560  27.722 5328  ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.417  26.224 5203  ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.770 1.816 . . 242 4207 94.2186  . . . . 0.264 . . . . . . . . . . . 0.287 
'X-RAY DIFFRACTION' 1.816 1.866 . . 202 4328 98.6283  . . . . 0.236 . . . . . . . . . . . 0.256 
'X-RAY DIFFRACTION' 1.866 1.920 . . 244 4253 99.9778  . . . . 0.205 . . . . . . . . . . . 0.230 
'X-RAY DIFFRACTION' 1.920 1.979 . . 226 4100 100.0000 . . . . 0.184 . . . . . . . . . . . 0.218 
'X-RAY DIFFRACTION' 1.979 2.044 . . 222 4024 100.0000 . . . . 0.170 . . . . . . . . . . . 0.224 
'X-RAY DIFFRACTION' 2.044 2.115 . . 193 3912 100.0000 . . . . 0.175 . . . . . . . . . . . 0.222 
'X-RAY DIFFRACTION' 2.115 2.195 . . 202 3735 100.0000 . . . . 0.141 . . . . . . . . . . . 0.174 
'X-RAY DIFFRACTION' 2.195 2.285 . . 197 3618 100.0000 . . . . 0.144 . . . . . . . . . . . 0.180 
'X-RAY DIFFRACTION' 2.285 2.386 . . 189 3482 100.0000 . . . . 0.145 . . . . . . . . . . . 0.198 
'X-RAY DIFFRACTION' 2.386 2.502 . . 200 3321 100.0000 . . . . 0.147 . . . . . . . . . . . 0.190 
'X-RAY DIFFRACTION' 2.502 2.637 . . 173 3140 100.0000 . . . . 0.143 . . . . . . . . . . . 0.179 
'X-RAY DIFFRACTION' 2.637 2.797 . . 157 3005 100.0000 . . . . 0.144 . . . . . . . . . . . 0.191 
'X-RAY DIFFRACTION' 2.797 2.990 . . 143 2859 100.0000 . . . . 0.138 . . . . . . . . . . . 0.181 
'X-RAY DIFFRACTION' 2.990 3.229 . . 142 2641 100.0000 . . . . 0.148 . . . . . . . . . . . 0.184 
'X-RAY DIFFRACTION' 3.229 3.536 . . 118 2467 100.0000 . . . . 0.163 . . . . . . . . . . . 0.219 
'X-RAY DIFFRACTION' 3.536 3.952 . . 128 2209 100.0000 . . . . 0.156 . . . . . . . . . . . 0.191 
'X-RAY DIFFRACTION' 3.952 4.561 . . 98  1977 100.0000 . . . . 0.128 . . . . . . . . . . . 0.148 
'X-RAY DIFFRACTION' 4.561 5.579 . . 82  1709 100.0000 . . . . 0.119 . . . . . . . . . . . 0.166 
'X-RAY DIFFRACTION' 5.579 7.862 . . 57  1349 100.0000 . . . . 0.163 . . . . . . . . . . . 0.207 
'X-RAY DIFFRACTION' 7.862 66.02 . . 51  793  99.8817  . . . . 0.169 . . . . . . . . . . . 0.214 
# 
_struct.entry_id                     9EOB 
_struct.title                        'Engineered GH181 sialidase from Akkermansia muciniphila' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EOB 
_struct_keywords.text            'Akkermansia muciniphila, gut microbiome, mucin, retaining mechanism, Sialidase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A  N N 1 ? 
B  N N 2 ? 
C  N N 3 ? 
D  N N 3 ? 
E  N N 3 ? 
F  N N 3 ? 
G  N N 3 ? 
H  N N 3 ? 
I  N N 3 ? 
J  N N 3 ? 
K  N N 3 ? 
L  N N 4 ? 
M  N N 3 ? 
N  N N 3 ? 
O  N N 3 ? 
P  N N 3 ? 
Q  N N 3 ? 
R  N N 3 ? 
S  N N 3 ? 
T  N N 3 ? 
U  N N 3 ? 
V  N N 5 ? 
W  N N 5 ? 
X  N N 5 ? 
Y  N N 5 ? 
Z  N N 5 ? 
AA N N 5 ? 
BA N N 5 ? 
CA N N 5 ? 
DA N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A7G6DVF6_9BACT 
_struct_ref.pdbx_db_accession          A0A7G6DVF6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PVPEPEVVATPPADAGRGLIRVDSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTRE
FIRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKGRRVIVPFHNMGGGTKFHISD
DGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVLEMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGT
LTMNTLGRLDDGTIVSLWTNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATLDGP
EDRGKHQSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQWTIHTYIPQKKGHCSYNRKPSAELV
QDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGATWNFPNGTTGLVKFRFRVADGEQADDSGLQVSLTDRLFNACDSTT
KDYALFTFPIRLRPAPHLLLGMKKVPFTPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGASYIHFISTGSQPDA
GILLDTVNARVK
;
_struct_ref.pdbx_align_begin           24 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9EOB 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 572 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A7G6DVF6 
_struct_ref_seq.db_align_beg                  24 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  595 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       24 
_struct_ref_seq.pdbx_auth_seq_align_end       595 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9EOB ALA A 326 ? UNP A0A7G6DVF6 HIS 349 conflict         349 1  
1 9EOB TYR A 327 ? UNP A0A7G6DVF6 GLN 350 conflict         350 2  
1 9EOB VAL A 454 ? UNP A0A7G6DVF6 ALA 477 conflict         477 3  
1 9EOB LYS A 493 ? UNP A0A7G6DVF6 ARG 516 conflict         516 4  
1 9EOB LEU A 573 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 596 5  
1 9EOB GLU A 574 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 597 6  
1 9EOB HIS A 575 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 598 7  
1 9EOB HIS A 576 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 599 8  
1 9EOB HIS A 577 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 600 9  
1 9EOB HIS A 578 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 601 10 
1 9EOB HIS A 579 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 602 11 
1 9EOB HIS A 580 ? UNP A0A7G6DVF6 ?   ?   'expression tag' 603 12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 4830  ? 
1 MORE         -23   ? 
1 'SSA (A^2)'  22990 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 GLU A 119 ? LEU A 124 ? GLU A 142 LEU A 147 5 ? 6 
HELX_P HELX_P2 AA2 ARG A 356 ? GLY A 360 ? ARG A 379 GLY A 383 1 ? 5 
HELX_P HELX_P3 AA3 THR A 368 ? TRP A 376 ? THR A 391 TRP A 399 1 ? 9 
HELX_P HELX_P4 AA4 ASP A 418 ? GLU A 420 ? ASP A 441 GLU A 443 5 ? 3 
HELX_P HELX_P5 AA5 THR A 479 ? ALA A 484 ? THR A 502 ALA A 507 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A GLU 276 OE1 ? ? ? 1_555 B NI . NI ? ? A GLU 299 A NI 701 1_555 ? ? ? ? ? ? ? 1.955 ? ? 
metalc2 metalc ? ? A GLU 276 OE2 ? ? ? 1_555 B NI . NI ? ? A GLU 299 A NI 701 1_555 ? ? ? ? ? ? ? 2.630 ? ? 
metalc3 metalc ? ? A HIS 388 NE2 ? ? ? 1_555 B NI . NI ? ? A HIS 411 A NI 701 1_555 ? ? ? ? ? ? ? 1.987 ? ? 
metalc4 metalc ? ? A HIS 576 NE2 ? ? ? 1_555 B NI . NI ? ? A HIS 599 A NI 701 3_545 ? ? ? ? ? ? ? 2.096 ? ? 
metalc5 metalc ? ? A HIS 578 NE2 ? ? ? 1_555 B NI . NI ? ? A HIS 601 A NI 701 3_545 ? ? ? ? ? ? ? 2.065 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE1 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 OE2 ? A GLU 276 ? A GLU 299 ? 1_555 53.2  ? 
2  OE1 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 388 ? A HIS 411 ? 1_555 96.1  ? 
3  OE2 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 388 ? A HIS 411 ? 1_555 137.3 ? 
4  OE1 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 576 ? A HIS 599 ? 1_555 68.2  ? 
5  OE2 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 576 ? A HIS 599 ? 1_555 60.0  ? 
6  NE2 ? A HIS 388 ? A HIS 411 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 576 ? A HIS 599 ? 1_555 142.2 ? 
7  OE1 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 578 ? A HIS 601 ? 1_555 69.0  ? 
8  OE2 ? A GLU 276 ? A GLU 299 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 578 ? A HIS 601 ? 1_555 59.1  ? 
9  NE2 ? A HIS 388 ? A HIS 411 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 578 ? A HIS 601 ? 1_555 144.0 ? 
10 NE2 ? A HIS 576 ? A HIS 599 ? 1_555 NI ? B NI . ? A NI 701 ? 1_555 NE2 ? A HIS 578 ? A HIS 601 ? 1_555 1.8   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PRO 182 A . ? PRO 205 A PRO 183 A ? PRO 206 A 1 7.23  
2 LYS 493 A . ? LYS 516 A PRO 494 A ? PRO 517 A 1 -1.47 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 5 ? 
AA4 ? 3 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 2 ? 
AB3 ? 2 ? 
AB4 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 6   ? ALA A 9   ? GLU A 29  ALA A 32  
AA1 2 ARG A 350 ? ASP A 355 ? ARG A 373 ASP A 378 
AA1 3 ARG A 337 ? GLN A 344 ? ARG A 360 GLN A 367 
AA1 4 GLY A 324 ? GLN A 332 ? GLY A 347 GLN A 355 
AA2 1 LEU A 19  ? ARG A 21  ? LEU A 42  ARG A 44  
AA2 2 ILE A 27  ? TYR A 30  ? ILE A 50  TYR A 53  
AA2 3 ASP A 38  ? SER A 42  ? ASP A 61  SER A 65  
AA2 4 GLU A 50  ? ALA A 53  ? GLU A 73  ALA A 76  
AA3 1 ALA A 71  ? ARG A 74  ? ALA A 94  ARG A 97  
AA3 2 PHE A 81  ? VAL A 84  ? PHE A 104 VAL A 107 
AA3 3 PHE A 92  ? ARG A 95  ? PHE A 115 ARG A 118 
AA3 4 LYS A 101 ? VAL A 105 ? LYS A 124 VAL A 128 
AA3 5 LEU A 111 ? GLU A 112 ? LEU A 134 GLU A 135 
AA4 1 ILE A 130 ? MET A 131 ? ILE A 153 MET A 154 
AA4 2 ARG A 142 ? ASN A 149 ? ARG A 165 ASN A 172 
AA4 3 VAL A 135 ? VAL A 137 ? VAL A 158 VAL A 160 
AA5 1 ILE A 130 ? MET A 131 ? ILE A 153 MET A 154 
AA5 2 ARG A 142 ? ASN A 149 ? ARG A 165 ASN A 172 
AA5 3 GLY A 153 ? SER A 159 ? GLY A 176 SER A 182 
AA5 4 HIS A 167 ? VAL A 168 ? HIS A 190 VAL A 191 
AA6 1 VAL A 194 ? GLU A 200 ? VAL A 217 GLU A 223 
AA6 2 LEU A 206 ? ARG A 211 ? LEU A 229 ARG A 234 
AA6 3 GLN A 216 ? SER A 222 ? GLN A 239 SER A 245 
AA6 4 GLU A 233 ? PHE A 238 ? GLU A 256 PHE A 261 
AA7 1 THR A 245 ? ARG A 248 ? THR A 268 ARG A 271 
AA7 2 ILE A 254 ? TRP A 258 ? ILE A 277 TRP A 281 
AA7 3 SER A 284 ? SER A 290 ? SER A 307 SER A 313 
AA7 4 TYR A 298 ? LEU A 305 ? TYR A 321 LEU A 328 
AA8 1 THR A 261 ? MET A 262 ? THR A 284 MET A 285 
AA8 2 LEU A 472 ? PHE A 473 ? LEU A 495 PHE A 496 
AA9 1 THR A 363 ? GLN A 367 ? THR A 386 GLN A 390 
AA9 2 ILE A 562 ? VAL A 571 ? ILE A 585 VAL A 594 
AA9 3 LYS A 409 ? ILE A 413 ? LYS A 432 ILE A 436 
AA9 4 GLU A 398 ? GLN A 401 ? GLU A 421 GLN A 424 
AB1 1 THR A 363 ? GLN A 367 ? THR A 386 GLN A 390 
AB1 2 ILE A 562 ? VAL A 571 ? ILE A 585 VAL A 594 
AB1 3 THR A 444 ? VAL A 453 ? THR A 467 VAL A 476 
AB1 4 TRP A 512 ? GLN A 520 ? TRP A 535 GLN A 543 
AB1 5 GLN A 523 ? LEU A 528 ? GLN A 546 LEU A 551 
AB1 6 LYS A 531 ? LYS A 537 ? LYS A 554 LYS A 560 
AB2 1 HIS A 379 ? TYR A 381 ? HIS A 402 TYR A 404 
AB2 2 ARG A 393 ? PRO A 395 ? ARG A 416 PRO A 418 
AB3 1 VAL A 422 ? ASN A 423 ? VAL A 445 ASN A 446 
AB3 2 VAL A 428 ? ASP A 429 ? VAL A 451 ASP A 452 
AB4 1 GLY A 434 ? GLY A 442 ? GLY A 457 GLY A 465 
AB4 2 ALA A 546 ? SER A 553 ? ALA A 569 SER A 576 
AB4 3 GLY A 463 ? THR A 469 ? GLY A 486 THR A 492 
AB4 4 PHE A 486 ? ARG A 491 ? PHE A 509 ARG A 514 
AB4 5 HIS A 497 ? LEU A 500 ? HIS A 520 LEU A 523 
AB4 6 LYS A 503 ? PRO A 506 ? LYS A 526 PRO A 529 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ALA A 9   ? N ALA A 32  O LEU A 351 ? O LEU A 374 
AA1 2 3 O ARG A 350 ? O ARG A 373 N LEU A 342 ? N LEU A 365 
AA1 3 4 O LEU A 339 ? O LEU A 362 N VAL A 331 ? N VAL A 354 
AA2 1 2 N ILE A 20  ? N ILE A 43  O ARG A 28  ? O ARG A 51  
AA2 2 3 N HIS A 29  ? N HIS A 52  O LEU A 40  ? O LEU A 63  
AA2 3 4 N VAL A 41  ? N VAL A 64  O GLU A 50  ? O GLU A 73  
AA3 1 2 N ALA A 71  ? N ALA A 94  O VAL A 84  ? O VAL A 107 
AA3 2 3 N PHE A 81  ? N PHE A 104 O SER A 94  ? O SER A 117 
AA3 3 4 N ARG A 95  ? N ARG A 118 O LYS A 101 ? O LYS A 124 
AA3 4 5 N ALA A 104 ? N ALA A 127 O GLU A 112 ? O GLU A 135 
AA4 1 2 N ILE A 130 ? N ILE A 153 O HIS A 148 ? O HIS A 171 
AA4 2 3 O ARG A 142 ? O ARG A 165 N VAL A 137 ? N VAL A 160 
AA5 1 2 N ILE A 130 ? N ILE A 153 O HIS A 148 ? O HIS A 171 
AA5 2 3 N VAL A 145 ? N VAL A 168 O HIS A 157 ? O HIS A 180 
AA5 3 4 N ILE A 158 ? N ILE A 181 O HIS A 167 ? O HIS A 190 
AA6 1 2 N LEU A 199 ? N LEU A 222 O TRP A 207 ? O TRP A 230 
AA6 2 3 N ALA A 210 ? N ALA A 233 O TRP A 218 ? O TRP A 241 
AA6 3 4 N ALA A 217 ? N ALA A 240 O SER A 235 ? O SER A 258 
AA7 1 2 N GLY A 247 ? N GLY A 270 O VAL A 255 ? O VAL A 278 
AA7 2 3 N TRP A 258 ? N TRP A 281 O HIS A 286 ? O HIS A 309 
AA7 3 4 N HIS A 285 ? N HIS A 308 O ILE A 303 ? O ILE A 326 
AA8 1 2 N MET A 262 ? N MET A 285 O LEU A 472 ? O LEU A 495 
AA9 1 2 N ARG A 364 ? N ARG A 387 O ALA A 569 ? O ALA A 592 
AA9 2 3 O ILE A 562 ? O ILE A 585 N ILE A 413 ? N ILE A 436 
AA9 3 4 O GLN A 412 ? O GLN A 435 N GLU A 398 ? N GLU A 421 
AB1 1 2 N ARG A 364 ? N ARG A 387 O ALA A 569 ? O ALA A 592 
AB1 2 3 O LEU A 563 ? O LEU A 586 N ARG A 452 ? N ARG A 475 
AB1 3 4 N PHE A 449 ? N PHE A 472 O ILE A 515 ? O ILE A 538 
AB1 4 5 N LEU A 518 ? N LEU A 541 O VAL A 525 ? O VAL A 548 
AB1 5 6 N VAL A 526 ? N VAL A 549 O ALA A 533 ? O ALA A 556 
AB2 1 2 N THR A 380 ? N THR A 403 O LYS A 394 ? O LYS A 417 
AB3 1 2 N ASN A 423 ? N ASN A 446 O VAL A 428 ? O VAL A 451 
AB4 1 2 N ALA A 435 ? N ALA A 458 O PHE A 551 ? O PHE A 574 
AB4 2 3 O ILE A 552 ? O ILE A 575 N GLN A 465 ? N GLN A 488 
AB4 3 4 N VAL A 466 ? N VAL A 489 O PHE A 488 ? O PHE A 511 
AB4 4 5 N ARG A 491 ? N ARG A 514 O HIS A 497 ? O HIS A 520 
AB4 5 6 N LEU A 498 ? N LEU A 521 O VAL A 505 ? O VAL A 528 
# 
_pdbx_entry_details.entry_id                   9EOB 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NH2 A ARG 438  ? B O A HOH 801  ? ? 1.59 
2 1 O   A HOH 1261 ? ? O A HOH 1327 ? ? 2.11 
3 1 OE1 A GLU 73   ? ? O A HOH 802  ? ? 2.15 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             250 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OE1 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             250 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.182 
_pdbx_validate_rmsd_bond.bond_target_value         1.252 
_pdbx_validate_rmsd_bond.bond_deviation            -0.070 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.011 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 58  ? ? -94.35  -150.26 
2  1 ASP A 137 ? ? -99.26  56.13   
3  1 ARG A 155 ? ? -107.56 -135.52 
4  1 ALA A 216 ? ? 38.23   67.70   
5  1 ASP A 300 ? ? -96.81  -73.42  
6  1 ASP A 300 ? ? -96.81  -78.07  
7  1 ASN A 304 ? ? -151.68 22.19   
8  1 ILE A 327 ? ? -170.56 148.69  
9  1 TYR A 350 ? ? 78.71   142.78  
10 1 ASP A 357 ? ? -160.65 -164.43 
11 1 HIS A 368 ? ? 85.05   140.03  
12 1 CYS A 412 ? ? -161.54 35.29   
13 1 ASN A 450 ? ? 70.91   47.97   
14 1 ASP A 588 ? ? -105.40 -87.84  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 97  ? ? 0.093 'SIDE CHAIN' 
2 1 ARG A 204 ? ? 0.073 'SIDE CHAIN' 
# 
_pdbx_unobs_or_zero_occ_residues.id               1 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_residues.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id     PRO 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id      24 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_residues.label_asym_id    A 
_pdbx_unobs_or_zero_occ_residues.label_comp_id    PRO 
_pdbx_unobs_or_zero_occ_residues.label_seq_id     1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
EDO C1   C  N N 89  
EDO O1   O  N N 90  
EDO C2   C  N N 91  
EDO O2   O  N N 92  
EDO H11  H  N N 93  
EDO H12  H  N N 94  
EDO HO1  H  N N 95  
EDO H21  H  N N 96  
EDO H22  H  N N 97  
EDO HO2  H  N N 98  
GLN N    N  N N 99  
GLN CA   C  N S 100 
GLN C    C  N N 101 
GLN O    O  N N 102 
GLN CB   C  N N 103 
GLN CG   C  N N 104 
GLN CD   C  N N 105 
GLN OE1  O  N N 106 
GLN NE2  N  N N 107 
GLN OXT  O  N N 108 
GLN H    H  N N 109 
GLN H2   H  N N 110 
GLN HA   H  N N 111 
GLN HB2  H  N N 112 
GLN HB3  H  N N 113 
GLN HG2  H  N N 114 
GLN HG3  H  N N 115 
GLN HE21 H  N N 116 
GLN HE22 H  N N 117 
GLN HXT  H  N N 118 
GLU N    N  N N 119 
GLU CA   C  N S 120 
GLU C    C  N N 121 
GLU O    O  N N 122 
GLU CB   C  N N 123 
GLU CG   C  N N 124 
GLU CD   C  N N 125 
GLU OE1  O  N N 126 
GLU OE2  O  N N 127 
GLU OXT  O  N N 128 
GLU H    H  N N 129 
GLU H2   H  N N 130 
GLU HA   H  N N 131 
GLU HB2  H  N N 132 
GLU HB3  H  N N 133 
GLU HG2  H  N N 134 
GLU HG3  H  N N 135 
GLU HE2  H  N N 136 
GLU HXT  H  N N 137 
GLY N    N  N N 138 
GLY CA   C  N N 139 
GLY C    C  N N 140 
GLY O    O  N N 141 
GLY OXT  O  N N 142 
GLY H    H  N N 143 
GLY H2   H  N N 144 
GLY HA2  H  N N 145 
GLY HA3  H  N N 146 
GLY HXT  H  N N 147 
HIS N    N  N N 148 
HIS CA   C  N S 149 
HIS C    C  N N 150 
HIS O    O  N N 151 
HIS CB   C  N N 152 
HIS CG   C  Y N 153 
HIS ND1  N  Y N 154 
HIS CD2  C  Y N 155 
HIS CE1  C  Y N 156 
HIS NE2  N  Y N 157 
HIS OXT  O  N N 158 
HIS H    H  N N 159 
HIS H2   H  N N 160 
HIS HA   H  N N 161 
HIS HB2  H  N N 162 
HIS HB3  H  N N 163 
HIS HD1  H  N N 164 
HIS HD2  H  N N 165 
HIS HE1  H  N N 166 
HIS HE2  H  N N 167 
HIS HXT  H  N N 168 
HOH O    O  N N 169 
HOH H1   H  N N 170 
HOH H2   H  N N 171 
ILE N    N  N N 172 
ILE CA   C  N S 173 
ILE C    C  N N 174 
ILE O    O  N N 175 
ILE CB   C  N S 176 
ILE CG1  C  N N 177 
ILE CG2  C  N N 178 
ILE CD1  C  N N 179 
ILE OXT  O  N N 180 
ILE H    H  N N 181 
ILE H2   H  N N 182 
ILE HA   H  N N 183 
ILE HB   H  N N 184 
ILE HG12 H  N N 185 
ILE HG13 H  N N 186 
ILE HG21 H  N N 187 
ILE HG22 H  N N 188 
ILE HG23 H  N N 189 
ILE HD11 H  N N 190 
ILE HD12 H  N N 191 
ILE HD13 H  N N 192 
ILE HXT  H  N N 193 
LEU N    N  N N 194 
LEU CA   C  N S 195 
LEU C    C  N N 196 
LEU O    O  N N 197 
LEU CB   C  N N 198 
LEU CG   C  N N 199 
LEU CD1  C  N N 200 
LEU CD2  C  N N 201 
LEU OXT  O  N N 202 
LEU H    H  N N 203 
LEU H2   H  N N 204 
LEU HA   H  N N 205 
LEU HB2  H  N N 206 
LEU HB3  H  N N 207 
LEU HG   H  N N 208 
LEU HD11 H  N N 209 
LEU HD12 H  N N 210 
LEU HD13 H  N N 211 
LEU HD21 H  N N 212 
LEU HD22 H  N N 213 
LEU HD23 H  N N 214 
LEU HXT  H  N N 215 
LYS N    N  N N 216 
LYS CA   C  N S 217 
LYS C    C  N N 218 
LYS O    O  N N 219 
LYS CB   C  N N 220 
LYS CG   C  N N 221 
LYS CD   C  N N 222 
LYS CE   C  N N 223 
LYS NZ   N  N N 224 
LYS OXT  O  N N 225 
LYS H    H  N N 226 
LYS H2   H  N N 227 
LYS HA   H  N N 228 
LYS HB2  H  N N 229 
LYS HB3  H  N N 230 
LYS HG2  H  N N 231 
LYS HG3  H  N N 232 
LYS HD2  H  N N 233 
LYS HD3  H  N N 234 
LYS HE2  H  N N 235 
LYS HE3  H  N N 236 
LYS HZ1  H  N N 237 
LYS HZ2  H  N N 238 
LYS HZ3  H  N N 239 
LYS HXT  H  N N 240 
MET N    N  N N 241 
MET CA   C  N S 242 
MET C    C  N N 243 
MET O    O  N N 244 
MET CB   C  N N 245 
MET CG   C  N N 246 
MET SD   S  N N 247 
MET CE   C  N N 248 
MET OXT  O  N N 249 
MET H    H  N N 250 
MET H2   H  N N 251 
MET HA   H  N N 252 
MET HB2  H  N N 253 
MET HB3  H  N N 254 
MET HG2  H  N N 255 
MET HG3  H  N N 256 
MET HE1  H  N N 257 
MET HE2  H  N N 258 
MET HE3  H  N N 259 
MET HXT  H  N N 260 
NI  NI   NI N N 261 
PEG C1   C  N N 262 
PEG O1   O  N N 263 
PEG C2   C  N N 264 
PEG O2   O  N N 265 
PEG C3   C  N N 266 
PEG C4   C  N N 267 
PEG O4   O  N N 268 
PEG H11  H  N N 269 
PEG H12  H  N N 270 
PEG HO1  H  N N 271 
PEG H21  H  N N 272 
PEG H22  H  N N 273 
PEG H31  H  N N 274 
PEG H32  H  N N 275 
PEG H41  H  N N 276 
PEG H42  H  N N 277 
PEG HO4  H  N N 278 
PHE N    N  N N 279 
PHE CA   C  N S 280 
PHE C    C  N N 281 
PHE O    O  N N 282 
PHE CB   C  N N 283 
PHE CG   C  Y N 284 
PHE CD1  C  Y N 285 
PHE CD2  C  Y N 286 
PHE CE1  C  Y N 287 
PHE CE2  C  Y N 288 
PHE CZ   C  Y N 289 
PHE OXT  O  N N 290 
PHE H    H  N N 291 
PHE H2   H  N N 292 
PHE HA   H  N N 293 
PHE HB2  H  N N 294 
PHE HB3  H  N N 295 
PHE HD1  H  N N 296 
PHE HD2  H  N N 297 
PHE HE1  H  N N 298 
PHE HE2  H  N N 299 
PHE HZ   H  N N 300 
PHE HXT  H  N N 301 
PRO N    N  N N 302 
PRO CA   C  N S 303 
PRO C    C  N N 304 
PRO O    O  N N 305 
PRO CB   C  N N 306 
PRO CG   C  N N 307 
PRO CD   C  N N 308 
PRO OXT  O  N N 309 
PRO H    H  N N 310 
PRO HA   H  N N 311 
PRO HB2  H  N N 312 
PRO HB3  H  N N 313 
PRO HG2  H  N N 314 
PRO HG3  H  N N 315 
PRO HD2  H  N N 316 
PRO HD3  H  N N 317 
PRO HXT  H  N N 318 
SER N    N  N N 319 
SER CA   C  N S 320 
SER C    C  N N 321 
SER O    O  N N 322 
SER CB   C  N N 323 
SER OG   O  N N 324 
SER OXT  O  N N 325 
SER H    H  N N 326 
SER H2   H  N N 327 
SER HA   H  N N 328 
SER HB2  H  N N 329 
SER HB3  H  N N 330 
SER HG   H  N N 331 
SER HXT  H  N N 332 
THR N    N  N N 333 
THR CA   C  N S 334 
THR C    C  N N 335 
THR O    O  N N 336 
THR CB   C  N R 337 
THR OG1  O  N N 338 
THR CG2  C  N N 339 
THR OXT  O  N N 340 
THR H    H  N N 341 
THR H2   H  N N 342 
THR HA   H  N N 343 
THR HB   H  N N 344 
THR HG1  H  N N 345 
THR HG21 H  N N 346 
THR HG22 H  N N 347 
THR HG23 H  N N 348 
THR HXT  H  N N 349 
TRP N    N  N N 350 
TRP CA   C  N S 351 
TRP C    C  N N 352 
TRP O    O  N N 353 
TRP CB   C  N N 354 
TRP CG   C  Y N 355 
TRP CD1  C  Y N 356 
TRP CD2  C  Y N 357 
TRP NE1  N  Y N 358 
TRP CE2  C  Y N 359 
TRP CE3  C  Y N 360 
TRP CZ2  C  Y N 361 
TRP CZ3  C  Y N 362 
TRP CH2  C  Y N 363 
TRP OXT  O  N N 364 
TRP H    H  N N 365 
TRP H2   H  N N 366 
TRP HA   H  N N 367 
TRP HB2  H  N N 368 
TRP HB3  H  N N 369 
TRP HD1  H  N N 370 
TRP HE1  H  N N 371 
TRP HE3  H  N N 372 
TRP HZ2  H  N N 373 
TRP HZ3  H  N N 374 
TRP HH2  H  N N 375 
TRP HXT  H  N N 376 
TYR N    N  N N 377 
TYR CA   C  N S 378 
TYR C    C  N N 379 
TYR O    O  N N 380 
TYR CB   C  N N 381 
TYR CG   C  Y N 382 
TYR CD1  C  Y N 383 
TYR CD2  C  Y N 384 
TYR CE1  C  Y N 385 
TYR CE2  C  Y N 386 
TYR CZ   C  Y N 387 
TYR OH   O  N N 388 
TYR OXT  O  N N 389 
TYR H    H  N N 390 
TYR H2   H  N N 391 
TYR HA   H  N N 392 
TYR HB2  H  N N 393 
TYR HB3  H  N N 394 
TYR HD1  H  N N 395 
TYR HD2  H  N N 396 
TYR HE1  H  N N 397 
TYR HE2  H  N N 398 
TYR HH   H  N N 399 
TYR HXT  H  N N 400 
VAL N    N  N N 401 
VAL CA   C  N S 402 
VAL C    C  N N 403 
VAL O    O  N N 404 
VAL CB   C  N N 405 
VAL CG1  C  N N 406 
VAL CG2  C  N N 407 
VAL OXT  O  N N 408 
VAL H    H  N N 409 
VAL H2   H  N N 410 
VAL HA   H  N N 411 
VAL HB   H  N N 412 
VAL HG11 H  N N 413 
VAL HG12 H  N N 414 
VAL HG13 H  N N 415 
VAL HG21 H  N N 416 
VAL HG22 H  N N 417 
VAL HG23 H  N N 418 
VAL HXT  H  N N 419 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PEG C1  O1   sing N N 246 
PEG C1  C2   sing N N 247 
PEG C1  H11  sing N N 248 
PEG C1  H12  sing N N 249 
PEG O1  HO1  sing N N 250 
PEG C2  O2   sing N N 251 
PEG C2  H21  sing N N 252 
PEG C2  H22  sing N N 253 
PEG O2  C3   sing N N 254 
PEG C3  C4   sing N N 255 
PEG C3  H31  sing N N 256 
PEG C3  H32  sing N N 257 
PEG C4  O4   sing N N 258 
PEG C4  H41  sing N N 259 
PEG C4  H42  sing N N 260 
PEG O4  HO4  sing N N 261 
PHE N   CA   sing N N 262 
PHE N   H    sing N N 263 
PHE N   H2   sing N N 264 
PHE CA  C    sing N N 265 
PHE CA  CB   sing N N 266 
PHE CA  HA   sing N N 267 
PHE C   O    doub N N 268 
PHE C   OXT  sing N N 269 
PHE CB  CG   sing N N 270 
PHE CB  HB2  sing N N 271 
PHE CB  HB3  sing N N 272 
PHE CG  CD1  doub Y N 273 
PHE CG  CD2  sing Y N 274 
PHE CD1 CE1  sing Y N 275 
PHE CD1 HD1  sing N N 276 
PHE CD2 CE2  doub Y N 277 
PHE CD2 HD2  sing N N 278 
PHE CE1 CZ   doub Y N 279 
PHE CE1 HE1  sing N N 280 
PHE CE2 CZ   sing Y N 281 
PHE CE2 HE2  sing N N 282 
PHE CZ  HZ   sing N N 283 
PHE OXT HXT  sing N N 284 
PRO N   CA   sing N N 285 
PRO N   CD   sing N N 286 
PRO N   H    sing N N 287 
PRO CA  C    sing N N 288 
PRO CA  CB   sing N N 289 
PRO CA  HA   sing N N 290 
PRO C   O    doub N N 291 
PRO C   OXT  sing N N 292 
PRO CB  CG   sing N N 293 
PRO CB  HB2  sing N N 294 
PRO CB  HB3  sing N N 295 
PRO CG  CD   sing N N 296 
PRO CG  HG2  sing N N 297 
PRO CG  HG3  sing N N 298 
PRO CD  HD2  sing N N 299 
PRO CD  HD3  sing N N 300 
PRO OXT HXT  sing N N 301 
SER N   CA   sing N N 302 
SER N   H    sing N N 303 
SER N   H2   sing N N 304 
SER CA  C    sing N N 305 
SER CA  CB   sing N N 306 
SER CA  HA   sing N N 307 
SER C   O    doub N N 308 
SER C   OXT  sing N N 309 
SER CB  OG   sing N N 310 
SER CB  HB2  sing N N 311 
SER CB  HB3  sing N N 312 
SER OG  HG   sing N N 313 
SER OXT HXT  sing N N 314 
THR N   CA   sing N N 315 
THR N   H    sing N N 316 
THR N   H2   sing N N 317 
THR CA  C    sing N N 318 
THR CA  CB   sing N N 319 
THR CA  HA   sing N N 320 
THR C   O    doub N N 321 
THR C   OXT  sing N N 322 
THR CB  OG1  sing N N 323 
THR CB  CG2  sing N N 324 
THR CB  HB   sing N N 325 
THR OG1 HG1  sing N N 326 
THR CG2 HG21 sing N N 327 
THR CG2 HG22 sing N N 328 
THR CG2 HG23 sing N N 329 
THR OXT HXT  sing N N 330 
TRP N   CA   sing N N 331 
TRP N   H    sing N N 332 
TRP N   H2   sing N N 333 
TRP CA  C    sing N N 334 
TRP CA  CB   sing N N 335 
TRP CA  HA   sing N N 336 
TRP C   O    doub N N 337 
TRP C   OXT  sing N N 338 
TRP CB  CG   sing N N 339 
TRP CB  HB2  sing N N 340 
TRP CB  HB3  sing N N 341 
TRP CG  CD1  doub Y N 342 
TRP CG  CD2  sing Y N 343 
TRP CD1 NE1  sing Y N 344 
TRP CD1 HD1  sing N N 345 
TRP CD2 CE2  doub Y N 346 
TRP CD2 CE3  sing Y N 347 
TRP NE1 CE2  sing Y N 348 
TRP NE1 HE1  sing N N 349 
TRP CE2 CZ2  sing Y N 350 
TRP CE3 CZ3  doub Y N 351 
TRP CE3 HE3  sing N N 352 
TRP CZ2 CH2  doub Y N 353 
TRP CZ2 HZ2  sing N N 354 
TRP CZ3 CH2  sing Y N 355 
TRP CZ3 HZ3  sing N N 356 
TRP CH2 HH2  sing N N 357 
TRP OXT HXT  sing N N 358 
TYR N   CA   sing N N 359 
TYR N   H    sing N N 360 
TYR N   H2   sing N N 361 
TYR CA  C    sing N N 362 
TYR CA  CB   sing N N 363 
TYR CA  HA   sing N N 364 
TYR C   O    doub N N 365 
TYR C   OXT  sing N N 366 
TYR CB  CG   sing N N 367 
TYR CB  HB2  sing N N 368 
TYR CB  HB3  sing N N 369 
TYR CG  CD1  doub Y N 370 
TYR CG  CD2  sing Y N 371 
TYR CD1 CE1  sing Y N 372 
TYR CD1 HD1  sing N N 373 
TYR CD2 CE2  doub Y N 374 
TYR CD2 HD2  sing N N 375 
TYR CE1 CZ   doub Y N 376 
TYR CE1 HE1  sing N N 377 
TYR CE2 CZ   sing Y N 378 
TYR CE2 HE2  sing N N 379 
TYR CZ  OH   sing N N 380 
TYR OH  HH   sing N N 381 
TYR OXT HXT  sing N N 382 
VAL N   CA   sing N N 383 
VAL N   H    sing N N 384 
VAL N   H2   sing N N 385 
VAL CA  C    sing N N 386 
VAL CA  CB   sing N N 387 
VAL CA  HA   sing N N 388 
VAL C   O    doub N N 389 
VAL C   OXT  sing N N 390 
VAL CB  CG1  sing N N 391 
VAL CB  CG2  sing N N 392 
VAL CB  HB   sing N N 393 
VAL CG1 HG11 sing N N 394 
VAL CG1 HG12 sing N N 395 
VAL CG1 HG13 sing N N 396 
VAL CG2 HG21 sing N N 397 
VAL CG2 HG22 sing N N 398 
VAL CG2 HG23 sing N N 399 
VAL OXT HXT  sing N N 400 
# 
_pdbx_audit_support.funding_organization   'Independent Research Fund Denmark - Medical Sciences' 
_pdbx_audit_support.country                Denmark 
_pdbx_audit_support.grant_number           1026-00386B 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8AXT 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9EOB 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013392 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011339 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.010042 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
CL 17 17 11.4601 0.0104  7.1962 1.1662  6.2554 18.5194 1.6455 47.7784 -9.3452  
H  1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
NI 28 28 12.8433 3.8785  7.2953 0.2565  4.4458 12.1763 2.3811 66.3421 1.0985   
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0486   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N  N   . VAL A  1 2   ? -21.323 -38.817 14.108  1.000 67.045 0 25   VAL A N   1 ? 
ATOM   2    C  CA  . VAL A  1 2   ? -21.702 -38.467 15.513  1.000 61.887 0 25   VAL A CA  1 ? 
ATOM   3    C  C   . VAL A  1 2   ? -22.023 -36.972 15.597  1.000 50.059 0 25   VAL A C   1 ? 
ATOM   4    O  O   . VAL A  1 2   ? -21.657 -36.210 14.708  1.000 43.447 0 25   VAL A O   1 ? 
ATOM   5    C  CB  . VAL A  1 2   ? -20.611 -38.934 16.494  1.000 60.622 0 25   VAL A CB  1 ? 
ATOM   6    C  CG1 . VAL A  1 2   ? -20.349 -37.925 17.609  1.000 57.782 0 25   VAL A CG1 1 ? 
ATOM   7    C  CG2 . VAL A  1 2   ? -20.929 -40.332 17.035  1.000 51.363 0 25   VAL A CG2 1 ? 
ATOM   8    N  N   . PRO A  1 3   ? -22.789 -36.534 16.624  1.000 48.845 0 26   PRO A N   1 ? 
ATOM   9    C  CA  . PRO A  1 3   ? -23.293 -35.164 16.720  1.000 43.018 0 26   PRO A CA  1 ? 
ATOM   10   C  C   . PRO A  1 3   ? -22.218 -34.092 16.581  1.000 34.144 0 26   PRO A C   1 ? 
ATOM   11   O  O   . PRO A  1 3   ? -21.198 -34.139 17.232  1.000 28.716 0 26   PRO A O   1 ? 
ATOM   12   C  CB  . PRO A  1 3   ? -23.957 -35.096 18.108  1.000 49.026 0 26   PRO A CB  1 ? 
ATOM   13   C  CG  . PRO A  1 3   ? -23.493 -36.351 18.805  1.000 46.005 0 26   PRO A CG  1 ? 
ATOM   14   C  CD  . PRO A  1 3   ? -23.338 -37.367 17.703  1.000 51.415 0 26   PRO A CD  1 ? 
ATOM   15   N  N   . GLU A  1 4   ? -22.493 -33.149 15.691  1.000 28.149 0 27   GLU A N   1 ? 
ATOM   16   C  CA  . GLU A  1 4   ? -21.738 -31.927 15.534  1.000 28.566 0 27   GLU A CA  1 ? 
ATOM   17   C  C   . GLU A  1 4   ? -21.994 -31.027 16.745  1.000 25.407 0 27   GLU A C   1 ? 
ATOM   18   O  O   . GLU A  1 4   ? -22.981 -31.167 17.466  1.000 26.320 0 27   GLU A O   1 ? 
ATOM   19   C  CB  . GLU A  1 4   ? -22.193 -31.247 14.234  1.000 28.656 0 27   GLU A CB  1 ? 
ATOM   20   C  CG  . GLU A  1 4   ? -21.909 -32.070 12.973  1.000 32.891 0 27   GLU A CG  1 ? 
ATOM   21   C  CD  . GLU A  1 4   ? -20.434 -32.116 12.602  1.000 34.810 0 27   GLU A CD  1 ? 
ATOM   22   O  OE1 . GLU A  1 4   ? -19.854 -31.039 12.559  1.000 39.321 0 27   GLU A OE1 1 ? 
ATOM   23   O  OE2 . GLU A  1 4   ? -19.865 -33.203 12.359  1.000 35.162 0 27   GLU A OE2 1 ? 
ATOM   24   N  N   . PRO A  1 5   ? -21.096 -30.073 17.021  1.000 22.282 0 28   PRO A N   1 ? 
ATOM   25   C  CA  . PRO A  1 5   ? -21.318 -29.103 18.097  1.000 22.980 0 28   PRO A CA  1 ? 
ATOM   26   C  C   . PRO A  1 5   ? -22.668 -28.434 17.924  1.000 23.716 0 28   PRO A C   1 ? 
ATOM   27   O  O   . PRO A  1 5   ? -23.037 -28.135 16.792  1.000 26.018 0 28   PRO A O   1 ? 
ATOM   28   C  CB  . PRO A  1 5   ? -20.185 -28.099 17.866  1.000 22.527 0 28   PRO A CB  1 ? 
ATOM   29   C  CG  . PRO A  1 5   ? -19.084 -28.956 17.321  1.000 24.775 0 28   PRO A CG  1 ? 
ATOM   30   C  CD  . PRO A  1 5   ? -19.811 -29.879 16.355  1.000 23.840 0 28   PRO A CD  1 ? 
ATOM   31   N  N   . GLU A  1 6   ? -23.345 -28.180 19.046  1.000 22.180 0 29   GLU A N   1 ? 
ATOM   32   C  CA  . GLU A  1 6   ? -24.674 -27.594 19.071  1.000 24.169 0 29   GLU A CA  1 ? 
ATOM   33   C  C   . GLU A  1 6   ? -24.652 -26.357 19.961  1.000 20.102 0 29   GLU A C   1 ? 
ATOM   34   O  O   . GLU A  1 6   ? -24.360 -26.468 21.143  1.000 19.481 0 29   GLU A O   1 ? 
ATOM   35   C  CB  . GLU A  1 6   ? -25.646 -28.643 19.618  1.000 27.110 0 29   GLU A CB  1 ? 
ATOM   36   C  CG  . GLU A  1 6   ? -27.088 -28.208 19.700  1.000 35.789 0 29   GLU A CG  1 ? 
ATOM   37   C  CD  . GLU A  1 6   ? -27.993 -29.170 20.470  1.000 45.915 0 29   GLU A CD  1 ? 
ATOM   38   O  OE1 . GLU A  1 6   ? -27.474 -30.180 21.041  1.000 48.815 0 29   GLU A OE1 1 ? 
ATOM   39   O  OE2 . GLU A  1 6   ? -29.212 -28.883 20.537  1.000 51.987 0 29   GLU A OE2 1 ? 
ATOM   40   N  N   . VAL A  1 7   ? -24.989 -25.196 19.392  1.000 20.036 0 30   VAL A N   1 ? 
ATOM   41   C  CA  . VAL A  1 7   ? -25.165 -24.017 20.209  1.000 20.940 0 30   VAL A CA  1 ? 
ATOM   42   C  C   . VAL A  1 7   ? -26.471 -24.125 20.987  1.000 23.169 0 30   VAL A C   1 ? 
ATOM   43   O  O   . VAL A  1 7   ? -27.513 -24.380 20.386  1.000 25.049 0 30   VAL A O   1 ? 
ATOM   44   C  CB  . VAL A  1 7   ? -25.152 -22.748 19.342  1.000 24.994 0 30   VAL A CB  1 ? 
ATOM   45   C  CG1 . VAL A  1 7   ? -25.540 -21.547 20.171  1.000 24.688 0 30   VAL A CG1 1 ? 
ATOM   46   C  CG2 . VAL A  1 7   ? -23.791 -22.558 18.677  1.000 30.475 0 30   VAL A CG2 1 ? 
ATOM   47   N  N   . VAL A  1 8   ? -26.447 -23.866 22.302  1.000 23.520 0 31   VAL A N   1 ? 
ATOM   48   C  CA  . VAL A  1 8   ? -27.638 -24.001 23.124  1.000 23.127 0 31   VAL A CA  1 ? 
ATOM   49   C  C   . VAL A  1 8   ? -28.066 -22.687 23.770  1.000 24.407 0 31   VAL A C   1 ? 
ATOM   50   O  O   . VAL A  1 8   ? -29.209 -22.588 24.199  1.000 25.520 0 31   VAL A O   1 ? 
ATOM   51   C  CB  . VAL A  1 8   ? -27.470 -25.083 24.205  1.000 25.909 0 31   VAL A CB  1 ? 
ATOM   52   C  CG1 . VAL A  1 8   ? -27.394 -26.451 23.584  1.000 26.957 0 31   VAL A CG1 1 ? 
ATOM   53   C  CG2 . VAL A  1 8   ? -26.264 -24.852 25.077  1.000 25.022 0 31   VAL A CG2 1 ? 
ATOM   54   N  N   . ALA A  1 9   ? -27.164 -21.727 23.951  1.000 24.256 0 32   ALA A N   1 ? 
ATOM   55   C  CA  . ALA A  1 9   ? -27.501 -20.460 24.596  1.000 24.194 0 32   ALA A CA  1 ? 
ATOM   56   C  C   . ALA A  1 9   ? -26.390 -19.438 24.407  1.000 26.119 0 32   ALA A C   1 ? 
ATOM   57   O  O   . ALA A  1 9   ? -25.342 -19.751 23.834  1.000 21.756 0 32   ALA A O   1 ? 
ATOM   58   C  CB  . ALA A  1 9   ? -27.754 -20.673 26.063  1.000 26.069 0 32   ALA A CB  1 ? 
ATOM   59   N  N   . THR A  1 10  ? -26.661 -18.221 24.911  1.000 24.077 0 33   THR A N   1 ? 
ATOM   60   C  CA  . THR A  1 10  ? -25.698 -17.150 25.005  1.000 23.449 0 33   THR A CA  1 ? 
ATOM   61   C  C   . THR A  1 10  ? -25.475 -16.910 26.492  1.000 23.402 0 33   THR A C   1 ? 
ATOM   62   O  O   . THR A  1 10  ? -26.455 -16.618 27.193  1.000 23.518 0 33   THR A O   1 ? 
ATOM   63   C  CB  . THR A  1 10  ? -26.257 -15.868 24.362  1.000 25.338 0 33   THR A CB  1 ? 
ATOM   64   O  OG1 . THR A  1 10  ? -26.442 -16.107 22.966  1.000 25.522 0 33   THR A OG1 1 ? 
ATOM   65   C  CG2 . THR A  1 10  ? -25.348 -14.683 24.576  1.000 24.269 0 33   THR A CG2 1 ? 
ATOM   66   N  N   . PRO A  1 11  ? -24.239 -17.031 27.031  1.000 21.075 0 34   PRO A N   1 ? 
ATOM   67   C  CA  . PRO A  1 11  ? -24.001 -16.758 28.445  1.000 21.116 0 34   PRO A CA  1 ? 
ATOM   68   C  C   . PRO A  1 11  ? -24.152 -15.272 28.740  1.000 20.577 0 34   PRO A C   1 ? 
ATOM   69   O  O   . PRO A  1 11  ? -24.046 -14.420 27.853  1.000 21.794 0 34   PRO A O   1 ? 
ATOM   70   C  CB  . PRO A  1 11  ? -22.565 -17.261 28.694  1.000 23.204 0 34   PRO A CB  1 ? 
ATOM   71   C  CG  . PRO A  1 11  ? -21.916 -17.115 27.352  1.000 22.651 0 34   PRO A CG  1 ? 
ATOM   72   C  CD  . PRO A  1 11  ? -23.004 -17.380 26.322  1.000 20.102 0 34   PRO A CD  1 ? 
ATOM   73   N  N   . PRO A  1 12  ? -24.488 -14.935 29.998  1.000 19.926 0 35   PRO A N   1 ? 
ATOM   74   C  CA  . PRO A  1 12  ? -24.732 -13.555 30.408  1.000 20.983 0 35   PRO A CA  1 ? 
ATOM   75   C  C   . PRO A  1 12  ? -23.472 -12.777 30.767  1.000 21.835 0 35   PRO A C   1 ? 
ATOM   76   O  O   . PRO A  1 12  ? -23.534 -11.659 31.279  1.000 22.282 0 35   PRO A O   1 ? 
ATOM   77   C  CB  . PRO A  1 12  ? -25.558 -13.797 31.671  1.000 20.601 0 35   PRO A CB  1 ? 
ATOM   78   C  CG  . PRO A  1 12  ? -24.942 -15.003 32.261  1.000 20.203 0 35   PRO A CG  1 ? 
ATOM   79   C  CD  . PRO A  1 12  ? -24.725 -15.909 31.078  1.000 19.737 0 35   PRO A CD  1 ? 
ATOM   80   N  N   . ALA A  1 13  ? -22.322 -13.391 30.494  1.000 21.879 0 36   ALA A N   1 ? 
ATOM   81   C  CA  . ALA A  1 13  ? -21.031 -12.740 30.640  1.000 20.009 0 36   ALA A CA  1 ? 
ATOM   82   C  C   . ALA A  1 13  ? -20.117 -13.400 29.623  1.000 19.942 0 36   ALA A C   1 ? 
ATOM   83   O  O   . ALA A  1 13  ? -20.415 -14.486 29.107  1.000 18.544 0 36   ALA A O   1 ? 
ATOM   84   C  CB  . ALA A  1 13  ? -20.500 -12.960 32.053  1.000 21.368 0 36   ALA A CB  1 ? 
ATOM   85   N  N   . ASP A  1 14  ? -19.000 -12.732 29.359  1.000 19.610 0 37   ASP A N   1 ? 
ATOM   86   C  CA  . ASP A  1 14  ? -17.966 -13.321 28.555  1.000 19.301 0 37   ASP A CA  1 ? 
ATOM   87   C  C   . ASP A  1 14  ? -17.601 -14.656 29.194  1.000 19.862 0 37   ASP A C   1 ? 
ATOM   88   O  O   . ASP A  1 14  ? -17.689 -14.860 30.390  1.000 21.470 0 37   ASP A O   1 ? 
ATOM   89   C  CB  . ASP A  1 14  ? -16.797 -12.358 28.383  1.000 18.992 0 37   ASP A CB  1 ? 
ATOM   90   C  CG  . ASP A  1 14  ? -17.063 -11.146 27.495  1.000 22.197 0 37   ASP A CG  1 ? 
ATOM   91   O  OD1 . ASP A  1 14  ? -18.213 -11.012 26.996  1.000 22.992 0 37   ASP A OD1 1 ? 
ATOM   92   O  OD2 . ASP A  1 14  ? -16.142 -10.338 27.338  1.000 20.446 0 37   ASP A OD2 1 ? 
ATOM   93   N  N   . ALA A  1 15  ? -17.130 -15.578 28.364  1.000 20.917 0 38   ALA A N   1 ? 
ATOM   94   C  CA  . ALA A  1 15  ? -16.752 -16.883 28.852  1.000 18.641 0 38   ALA A CA  1 ? 
ATOM   95   C  C   . ALA A  1 15  ? -15.449 -16.812 29.647  1.000 21.806 0 38   ALA A C   1 ? 
ATOM   96   O  O   . ALA A  1 15  ? -14.691 -15.856 29.530  1.000 19.356 0 38   ALA A O   1 ? 
ATOM   97   C  CB  . ALA A  1 15  ? -16.582 -17.811 27.679  1.000 18.821 0 38   ALA A CB  1 ? 
ATOM   98   N  N   . GLY A  1 16  ? -15.223 -17.831 30.481  1.000 19.807 0 39   GLY A N   1 ? 
ATOM   99   C  CA  . GLY A  1 16  ? -13.949 -18.007 31.168  1.000 19.919 0 39   GLY A CA  1 ? 
ATOM   100  C  C   . GLY A  1 16  ? -14.104 -18.186 32.678  1.000 18.745 0 39   GLY A C   1 ? 
ATOM   101  O  O   . GLY A  1 16  ? -13.207 -18.679 33.358  1.000 20.180 0 39   GLY A O   1 ? 
ATOM   102  N  N   . ARG A  1 17  ? -15.214 -17.684 33.201  1.000 19.017 0 40   ARG A N   1 ? 
ATOM   103  C  CA  . ARG A  1 17  ? -15.501 -17.682 34.622  1.000 19.484 0 40   ARG A CA  1 ? 
ATOM   104  C  C   . ARG A  1 17  ? -17.022 -17.725 34.782  1.000 19.253 0 40   ARG A C   1 ? 
ATOM   105  O  O   . ARG A  1 17  ? -17.733 -17.063 34.023  1.000 21.037 0 40   ARG A O   1 ? 
ATOM   106  C  CB  . ARG A  1 17  ? -14.957 -16.421 35.323  1.000 17.400 0 40   ARG A CB  1 ? 
ATOM   107  C  CG  . ARG A  1 17  ? -13.463 -16.154 35.141  1.000 16.865 0 40   ARG A CG  1 ? 
ATOM   108  C  CD  . ARG A  1 17  ? -13.078 -14.775 35.686  1.000 15.915 0 40   ARG A CD  1 ? 
ATOM   109  N  NE  . ARG A  1 17  ? -11.680 -14.508 35.464  1.000 16.842 0 40   ARG A NE  1 ? 
ATOM   110  C  CZ  . ARG A  1 17  ? -11.151 -14.074 34.323  1.000 16.769 0 40   ARG A CZ  1 ? 
ATOM   111  N  NH1 . ARG A  1 17  ? -11.892 -13.946 33.226  1.000 18.686 0 40   ARG A NH1 1 ? 
ATOM   112  N  NH2 . ARG A  1 17  ? -9.875  -13.766 34.279  1.000 17.398 0 40   ARG A NH2 1 ? 
ATOM   113  N  N   . GLY A  1 18  ? -17.451 -18.396 35.847  1.000 20.415 0 41   GLY A N   1 ? 
ATOM   114  C  CA  . GLY A  1 18  ? -18.804 -18.294 36.363  1.000 20.091 0 41   GLY A CA  1 ? 
ATOM   115  C  C   . GLY A  1 18  ? -19.710 -19.459 35.969  1.000 20.457 0 41   GLY A C   1 ? 
ATOM   116  O  O   . GLY A  1 18  ? -20.865 -19.498 36.391  1.000 21.545 0 41   GLY A O   1 ? 
ATOM   117  N  N   . LEU A  1 19  ? -19.184 -20.403 35.167  1.000 20.794 0 42   LEU A N   1 ? 
ATOM   118  C  CA  . LEU A  1 19  ? -19.950 -21.575 34.752  1.000 20.830 0 42   LEU A CA  1 ? 
ATOM   119  C  C   . LEU A  1 19  ? -19.743 -22.660 35.805  1.000 20.978 0 42   LEU A C   1 ? 
ATOM   120  O  O   . LEU A  1 19  ? -18.601 -23.003 36.105  1.000 20.585 0 42   LEU A O   1 ? 
ATOM   121  C  CB  . LEU A  1 19  ? -19.482 -22.055 33.371  1.000 20.517 0 42   LEU A CB  1 ? 
ATOM   122  C  CG  . LEU A  1 19  ? -20.176 -23.326 32.875  1.000 20.863 0 42   LEU A CG  1 ? 
ATOM   123  C  CD1 . LEU A  1 19  ? -21.645 -23.043 32.587  1.000 20.334 0 42   LEU A CD1 1 ? 
ATOM   124  C  CD2 . LEU A  1 19  ? -19.457 -23.875 31.652  1.000 21.596 0 42   LEU A CD2 1 ? 
ATOM   125  N  N   . ILE A  1 20  ? -20.845 -23.137 36.433  1.000 21.068 0 43   ILE A N   1 ? 
ATOM   126  C  CA  . ILE A  1 20  ? -20.695 -24.038 37.563  1.000 20.713 0 43   ILE A CA  1 ? 
ATOM   127  C  C   . ILE A  1 20  ? -21.842 -25.041 37.640  1.000 22.392 0 43   ILE A C   1 ? 
ATOM   128  O  O   . ILE A  1 20  ? -23.005 -24.661 37.590  1.000 23.185 0 43   ILE A O   1 ? 
ATOM   129  C  CB  . ILE A  1 20  ? -20.540 -23.247 38.881  1.000 22.908 0 43   ILE A CB  1 ? 
ATOM   130  C  CG1 . ILE A  1 20  ? -20.334 -24.178 40.083  1.000 22.950 0 43   ILE A CG1 1 ? 
ATOM   131  C  CG2 . ILE A  1 20  ? -21.686 -22.269 39.126  1.000 21.829 0 43   ILE A CG2 1 ? 
ATOM   132  C  CD1 . ILE A  1 20  ? -18.982 -24.839 40.130  1.000 23.453 0 43   ILE A CD1 1 ? 
ATOM   133  N  N   . ARG A  1 21  ? -21.482 -26.313 37.821  1.000 21.943 0 44   ARG A N   1 ? 
ATOM   134  C  CA  . ARG A  1 21  ? -22.473 -27.344 38.086  1.000 26.449 0 44   ARG A CA  1 ? 
ATOM   135  C  C   . ARG A  1 21  ? -22.947 -27.270 39.542  1.000 26.126 0 44   ARG A C   1 ? 
ATOM   136  O  O   . ARG A  1 21  ? -22.134 -27.249 40.464  1.000 26.192 0 44   ARG A O   1 ? 
ATOM   137  C  CB  . ARG A  1 21  ? -21.902 -28.731 37.782  1.000 24.765 0 44   ARG A CB  1 ? 
ATOM   138  C  CG  . ARG A  1 21  ? -22.914 -29.843 38.064  1.000 28.165 0 44   ARG A CG  1 ? 
ATOM   139  C  CD  . ARG A  1 21  ? -22.404 -31.228 37.693  1.000 24.999 0 44   ARG A CD  1 ? 
ATOM   140  N  NE  . ARG A  1 21  ? -22.445 -31.446 36.254  1.000 25.548 0 44   ARG A NE  1 ? 
ATOM   141  C  CZ  . ARG A  1 21  ? -23.520 -31.669 35.503  1.000 25.263 0 44   ARG A CZ  1 ? 
ATOM   142  N  NH1 . ARG A  1 21  ? -24.750 -31.556 35.988  1.000 26.076 0 44   ARG A NH1 1 ? 
ATOM   143  N  NH2 . ARG A  1 21  ? -23.374 -31.937 34.216  1.000 28.119 0 44   ARG A NH2 1 ? 
ATOM   144  N  N   . VAL A  1 22  ? -24.271 -27.204 39.722  1.000 27.771 0 45   VAL A N   1 ? 
ATOM   145  C  CA  . VAL A  1 22  ? -24.915 -27.189 41.032  1.000 27.890 0 45   VAL A CA  1 ? 
ATOM   146  C  C   . VAL A  1 22  ? -25.213 -28.629 41.468  1.000 30.880 0 45   VAL A C   1 ? 
ATOM   147  O  O   . VAL A  1 22  ? -24.862 -29.019 42.574  1.000 30.315 0 45   VAL A O   1 ? 
ATOM   148  C  CB  . VAL A  1 22  ? -26.198 -26.349 40.987  1.000 30.683 0 45   VAL A CB  1 ? 
ATOM   149  C  CG1 . VAL A  1 22  ? -26.902 -26.283 42.346  1.000 32.323 0 45   VAL A CG1 1 ? 
ATOM   150  C  CG2 . VAL A  1 22  ? -25.889 -24.958 40.472  1.000 28.898 0 45   VAL A CG2 1 ? 
ATOM   151  N  N   . ASP A  1 23  ? -25.863 -29.413 40.599  1.000 27.810 0 46   ASP A N   1 ? 
ATOM   152  C  CA  . ASP A  1 23  ? -26.128 -30.824 40.884  1.000 29.522 0 46   ASP A CA  1 ? 
ATOM   153  C  C   . ASP A  1 23  ? -26.222 -31.590 39.565  1.000 29.872 0 46   ASP A C   1 ? 
ATOM   154  O  O   . ASP A  1 23  ? -25.822 -31.073 38.523  1.000 28.752 0 46   ASP A O   1 ? 
ATOM   155  C  CB  . ASP A  1 23  ? -27.380 -30.997 41.760  1.000 32.720 0 46   ASP A CB  1 ? 
ATOM   156  C  CG  . ASP A  1 23  ? -28.697 -30.506 41.185  1.000 34.283 0 46   ASP A CG  1 ? 
ATOM   157  O  OD1 . ASP A  1 23  ? -28.889 -30.597 39.958  1.000 33.912 0 46   ASP A OD1 1 ? 
ATOM   158  O  OD2 . ASP A  1 23  ? -29.518 -30.006 41.987  1.000 35.639 0 46   ASP A OD2 1 ? 
ATOM   159  N  N   . SER A  1 24  ? -26.725 -32.836 39.568  1.000 31.803 0 47   SER A N   1 ? 
ATOM   160  C  CA  . SER A  1 24  ? -26.638 -33.642 38.353  1.000 26.993 0 47   SER A CA  1 ? 
ATOM   161  C  C   . SER A  1 24  ? -27.495 -33.037 37.235  1.000 27.038 0 47   SER A C   1 ? 
ATOM   162  O  O   . SER A  1 24  ? -27.295 -33.347 36.066  1.000 29.729 0 47   SER A O   1 ? 
ATOM   163  C  CB  . SER A  1 24  ? -26.985 -35.095 38.629  1.000 33.522 0 47   SER A CB  1 ? 
ATOM   164  O  OG  . SER A  1 24  ? -28.348 -35.169 38.995  1.000 31.715 0 47   SER A OG  1 ? 
ATOM   165  N  N   . ARG A  1 25  ? -28.450 -32.157 37.539  1.000 29.536 0 48   ARG A N   1 ? 
ATOM   166  C  CA  . ARG A  1 25  ? -29.299 -31.622 36.487  1.000 28.777 0 48   ARG A CA  1 ? 
ATOM   167  C  C   . ARG A  1 25  ? -29.190 -30.101 36.349  1.000 29.496 0 48   ARG A C   1 ? 
ATOM   168  O  O   . ARG A  1 25  ? -29.653 -29.533 35.339  1.000 30.208 0 48   ARG A O   1 ? 
ATOM   169  C  CB  . ARG A  1 25  ? -30.732 -32.110 36.726  1.000 37.904 0 48   ARG A CB  1 ? 
ATOM   170  C  CG  . ARG A  1 25  ? -30.865 -33.619 36.527  1.000 45.465 0 48   ARG A CG  1 ? 
ATOM   171  C  CD  . ARG A  1 25  ? -32.228 -34.124 36.073  1.000 53.219 0 48   ARG A CD  1 ? 
ATOM   172  N  NE  . ARG A  1 25  ? -32.630 -33.703 34.723  1.000 56.991 0 48   ARG A NE  1 ? 
ATOM   173  C  CZ  . ARG A  1 25  ? -32.030 -34.029 33.571  1.000 57.541 0 48   ARG A CZ  1 ? 
ATOM   174  N  NH1 . ARG A  1 25  ? -30.916 -34.742 33.534  1.000 60.788 0 48   ARG A NH1 1 ? 
ATOM   175  N  NH2 . ARG A  1 25  ? -32.558 -33.630 32.431  1.000 60.488 0 48   ARG A NH2 1 ? 
ATOM   176  N  N   . GLU A  1 26  ? -28.678 -29.423 37.391  1.000 24.680 0 49   GLU A N   1 ? 
ATOM   177  C  CA  . GLU A  1 26  ? -28.693 -27.965 37.400  1.000 26.053 0 49   GLU A CA  1 ? 
ATOM   178  C  C   . GLU A  1 26  ? -27.276 -27.426 37.159  1.000 22.464 0 49   GLU A C   1 ? 
ATOM   179  O  O   . GLU A  1 26  ? -26.349 -27.834 37.831  1.000 23.601 0 49   GLU A O   1 ? 
ATOM   180  C  CB  . GLU A  1 26  ? -29.261 -27.412 38.707  1.000 26.564 0 49   GLU A CB  1 ? 
ATOM   181  C  CG  . GLU A  1 26  ? -29.417 -25.895 38.690  1.000 27.138 0 49   GLU A CG  1 ? 
ATOM   182  C  CD  . GLU A  1 26  ? -30.149 -25.265 39.867  1.000 34.038 0 49   GLU A CD  1 ? 
ATOM   183  O  OE1 . GLU A  1 26  ? -30.844 -26.041 40.594  1.000 34.068 0 49   GLU A OE1 1 ? 
ATOM   184  O  OE2 . GLU A  1 26  ? -30.027 -23.986 40.061  1.000 31.186 0 49   GLU A OE2 1 ? 
ATOM   185  N  N   . ILE A  1 27  ? -27.154 -26.501 36.185  1.000 26.398 0 50   ILE A N   1 ? 
ATOM   186  C  CA  . ILE A  1 27  ? -25.898 -25.835 35.853  1.000 24.598 0 50   ILE A CA  1 ? 
ATOM   187  C  C   . ILE A  1 27  ? -26.208 -24.345 35.745  1.000 23.162 0 50   ILE A C   1 ? 
ATOM   188  O  O   . ILE A  1 27  ? -27.254 -23.947 35.182  1.000 22.913 0 50   ILE A O   1 ? 
ATOM   189  C  CB  . ILE A  1 27  ? -25.313 -26.389 34.531  1.000 25.703 0 50   ILE A CB  1 ? 
ATOM   190  C  CG1 . ILE A  1 27  ? -25.127 -27.909 34.575  1.000 26.640 0 50   ILE A CG1 1 ? 
ATOM   191  C  CG2 . ILE A  1 27  ? -24.009 -25.677 34.150  1.000 25.695 0 50   ILE A CG2 1 ? 
ATOM   192  C  CD1 . ILE A  1 27  ? -24.894 -28.535 33.206  1.000 25.422 0 50   ILE A CD1 1 ? 
ATOM   193  N  N   . ARG A  1 28  ? -25.292 -23.524 36.269  1.000 21.241 0 51   ARG A N   1 ? 
ATOM   194  C  CA  . ARG A  1 28  ? -25.499 -22.085 36.253  1.000 21.898 0 51   ARG A CA  1 ? 
ATOM   195  C  C   . ARG A  1 28  ? -24.329 -21.385 35.575  1.000 18.595 0 51   ARG A C   1 ? 
ATOM   196  O  O   . ARG A  1 28  ? -23.229 -21.866 35.636  1.000 20.389 0 51   ARG A O   1 ? 
ATOM   197  C  CB  . ARG A  1 28  ? -25.612 -21.547 37.681  1.000 22.260 0 51   ARG A CB  1 ? 
ATOM   198  C  CG  . ARG A  1 28  ? -26.910 -21.903 38.383  1.000 23.838 0 51   ARG A CG  1 ? 
ATOM   199  C  CD  . ARG A  1 28  ? -26.899 -21.459 39.836  1.000 25.813 0 51   ARG A CD  1 ? 
ATOM   200  N  NE  . ARG A  1 28  ? -27.970 -22.091 40.594  1.000 26.274 0 51   ARG A NE  1 ? 
ATOM   201  C  CZ  . ARG A  1 28  ? -28.267 -21.795 41.844  1.000 28.720 0 51   ARG A CZ  1 ? 
ATOM   202  N  NH1 . ARG A  1 28  ? -27.637 -20.821 42.470  1.000 25.133 0 51   ARG A NH1 1 ? 
ATOM   203  N  NH2 . ARG A  1 28  ? -29.231 -22.454 42.460  1.000 28.662 0 51   ARG A NH2 1 ? 
ATOM   204  N  N   . HIS A  1 29  ? -24.597 -20.222 34.997  1.000 19.592 0 52   HIS A N   1 ? 
ATOM   205  C  CA  . HIS A  1 29  ? -23.549 -19.318 34.575  1.000 20.595 0 52   HIS A CA  1 ? 
ATOM   206  C  C   . HIS A  1 29  ? -23.828 -17.965 35.193  1.000 20.436 0 52   HIS A C   1 ? 
ATOM   207  O  O   . HIS A  1 29  ? -24.834 -17.326 34.853  1.000 21.810 0 52   HIS A O   1 ? 
ATOM   208  C  CB  . HIS A  1 29  ? -23.516 -19.194 33.043  1.000 21.502 0 52   HIS A CB  1 ? 
ATOM   209  C  CG  . HIS A  1 29  ? -22.212 -18.653 32.526  1.000 20.452 0 52   HIS A CG  1 ? 
ATOM   210  N  ND1 . HIS A  1 29  ? -21.665 -17.452 32.942  1.000 22.297 0 52   HIS A ND1 1 ? 
ATOM   211  C  CD2 . HIS A  1 29  ? -21.367 -19.162 31.602  1.000 22.832 0 52   HIS A CD2 1 ? 
ATOM   212  C  CE1 . HIS A  1 29  ? -20.481 -17.282 32.305  1.000 22.623 0 52   HIS A CE1 1 ? 
ATOM   213  N  NE2 . HIS A  1 29  ? -20.306 -18.295 31.453  1.000 22.924 0 52   HIS A NE2 1 ? 
ATOM   214  N  N   . TYR A  1 30  ? -22.940 -17.534 36.095  1.000 21.530 0 53   TYR A N   1 ? 
ATOM   215  C  CA  . TYR A  1 30  ? -23.086 -16.248 36.745  1.000 19.688 0 53   TYR A CA  1 ? 
ATOM   216  C  C   . TYR A  1 30  ? -22.617 -15.139 35.812  1.000 20.801 0 53   TYR A C   1 ? 
ATOM   217  O  O   . TYR A  1 30  ? -22.192 -15.389 34.684  1.000 18.815 0 53   TYR A O   1 ? 
ATOM   218  C  CB  . TYR A  1 30  ? -22.387 -16.276 38.101  1.000 20.926 0 53   TYR A CB  1 ? 
ATOM   219  C  CG  . TYR A  1 30  ? -23.193 -17.008 39.181  1.000 20.472 0 53   TYR A CG  1 ? 
ATOM   220  C  CD1 . TYR A  1 30  ? -23.228 -18.401 39.220  1.000 22.313 0 53   TYR A CD1 1 ? 
ATOM   221  C  CD2 . TYR A  1 30  ? -23.943 -16.313 40.120  1.000 22.038 0 53   TYR A CD2 1 ? 
ATOM   222  C  CE1 . TYR A  1 30  ? -23.921 -19.077 40.208  1.000 21.429 0 53   TYR A CE1 1 ? 
ATOM   223  C  CE2 . TYR A  1 30  ? -24.638 -16.979 41.122  1.000 20.492 0 53   TYR A CE2 1 ? 
ATOM   224  C  CZ  . TYR A  1 30  ? -24.627 -18.358 41.160  1.000 20.849 0 53   TYR A CZ  1 ? 
ATOM   225  O  OH  . TYR A  1 30  ? -25.351 -19.025 42.095  1.000 21.722 0 53   TYR A OH  1 ? 
ATOM   226  N  N   . SER A  1 31  ? -22.750 -13.896 36.301  1.000 20.855 0 54   SER A N   1 ? 
ATOM   227  C  CA  . SER A  1 31  ? -22.587 -12.711 35.479  1.000 21.652 0 54   SER A CA  1 ? 
ATOM   228  C  C   . SER A  1 31  ? -21.729 -11.709 36.220  1.000 19.140 0 54   SER A C   1 ? 
ATOM   229  O  O   . SER A  1 31  ? -21.569 -11.819 37.428  1.000 20.937 0 54   SER A O   1 ? 
ATOM   230  C  CB  . SER A  1 31  ? -23.944 -12.099 35.120  1.000 23.448 0 54   SER A CB  1 ? 
ATOM   231  O  OG  . SER A  1 31  ? -24.400 -11.258 36.175  1.000 22.862 0 54   SER A OG  1 ? 
ATOM   232  N  N   . GLY A  1 32  ? -21.277 -10.693 35.483  1.000 19.629 0 55   GLY A N   1 ? 
ATOM   233  C  CA  . GLY A  1 32  ? -20.594 -9.551  36.045  1.000 21.697 0 55   GLY A CA  1 ? 
ATOM   234  C  C   . GLY A  1 32  ? -21.528 -8.375  36.336  1.000 20.612 0 55   GLY A C   1 ? 
ATOM   235  O  O   . GLY A  1 32  ? -21.053 -7.257  36.489  1.000 21.580 0 55   GLY A O   1 ? 
ATOM   236  N  N   . THR A  1 33  ? -22.836 -8.616  36.467  1.000 21.329 0 56   THR A N   1 ? 
ATOM   237  C  CA  . THR A  1 33  ? -23.739 -7.480  36.627  1.000 22.311 0 56   THR A CA  1 ? 
ATOM   238  C  C   . THR A  1 33  ? -23.340 -6.623  37.840  1.000 21.090 0 56   THR A C   1 ? 
ATOM   239  O  O   . THR A  1 33  ? -22.912 -7.142  38.875  1.000 21.177 0 56   THR A O   1 ? 
ATOM   240  C  CB  . THR A  1 33  ? -25.208 -7.909  36.791  1.000 26.912 0 56   THR A CB  1 ? 
ATOM   241  O  OG1 . THR A  1 33  ? -25.953 -6.699  36.943  1.000 28.818 0 56   THR A OG1 1 ? 
ATOM   242  C  CG2 . THR A  1 33  ? -25.453 -8.802  37.988  1.000 25.953 0 56   THR A CG2 1 ? 
ATOM   243  N  N   . ARG A  1 34  ? -23.453 -5.289  37.698  1.000 21.393 0 57   ARG A N   1 ? 
ATOM   244  C  CA  . ARG A  1 34  ? -23.219 -4.356  38.811  1.000 23.469 0 57   ARG A CA  1 ? 
ATOM   245  C  C   . ARG A  1 34  ? -24.496 -4.182  39.625  1.000 30.825 0 57   ARG A C   1 ? 
ATOM   246  O  O   . ARG A  1 34  ? -24.459 -3.596  40.706  1.000 32.227 0 57   ARG A O   1 ? 
ATOM   247  C  CB  . ARG A  1 34  ? -22.791 -2.955  38.344  1.000 24.964 0 57   ARG A CB  1 ? 
ATOM   248  C  CG  . ARG A  1 34  ? -21.566 -2.893  37.436  1.000 25.832 0 57   ARG A CG  1 ? 
ATOM   249  C  CD  . ARG A  1 34  ? -20.304 -3.334  38.185  1.000 26.493 0 57   ARG A CD  1 ? 
ATOM   250  N  NE  . ARG A  1 34  ? -20.041 -4.756  38.022  1.000 29.326 0 57   ARG A NE  1 ? 
ATOM   251  C  CZ  . ARG A  1 34  ? -19.023 -5.432  38.583  1.000 28.637 0 57   ARG A CZ  1 ? 
ATOM   252  N  NH1 . ARG A  1 34  ? -18.265 -4.837  39.493  1.000 26.723 0 57   ARG A NH1 1 ? 
ATOM   253  N  NH2 . ARG A  1 34  ? -18.831 -6.723  38.288  1.000 26.903 0 57   ARG A NH2 1 ? 
ATOM   254  N  N   . LYS A  1 35  ? -25.615 -4.710  39.147  1.000 30.371 0 58   LYS A N   1 ? 
ATOM   255  C  CA  . LYS A  1 35  ? -26.871 -4.565  39.870  1.000 35.262 0 58   LYS A CA  1 ? 
ATOM   256  C  C   . LYS A  1 35  ? -27.063 -5.798  40.745  1.000 31.345 0 58   LYS A C   1 ? 
ATOM   257  O  O   . LYS A  1 35  ? -26.085 -6.387  41.214  1.000 32.362 0 58   LYS A O   1 ? 
ATOM   258  C  CB  . LYS A  1 35  ? -28.024 -4.349  38.887  1.000 40.046 0 58   LYS A CB  1 ? 
ATOM   259  C  CG  . LYS A  1 35  ? -27.937 -3.078  38.054  1.000 46.893 0 58   LYS A CG  1 ? 
ATOM   260  C  CD  . LYS A  1 35  ? -29.090 -2.968  37.059  1.000 58.043 0 58   LYS A CD  1 ? 
ATOM   261  C  CE  . LYS A  1 35  ? -28.737 -2.236  35.780  1.000 64.077 0 58   LYS A CE  1 ? 
ATOM   262  N  NZ  . LYS A  1 35  ? -28.361 -0.828  36.057  1.000 62.662 0 58   LYS A NZ  1 ? 
ATOM   263  N  N   . GLU A  1 36  ? -28.322 -6.176  40.998  1.000 32.427 0 59   GLU A N   1 ? 
ATOM   264  C  CA  . GLU A  1 36  ? -28.591 -7.341  41.820  1.000 31.718 0 59   GLU A CA  1 ? 
ATOM   265  C  C   . GLU A  1 36  ? -28.102 -8.584  41.084  1.000 27.667 0 59   GLU A C   1 ? 
ATOM   266  O  O   . GLU A  1 36  ? -28.359 -8.760  39.897  1.000 25.220 0 59   GLU A O   1 ? 
ATOM   267  C  CB  . GLU A  1 36  ? -30.069 -7.387  42.237  1.000 36.384 0 59   GLU A CB  1 ? 
ATOM   268  C  CG  . GLU A  1 36  ? -30.346 -6.456  43.424  1.000 40.503 0 59   GLU A CG  1 ? 
ATOM   269  C  CD  . GLU A  1 36  ? -31.757 -6.467  43.999  1.000 56.835 0 59   GLU A CD  1 ? 
ATOM   270  O  OE1 . GLU A  1 36  ? -32.643 -7.152  43.435  1.000 63.177 0 59   GLU A OE1 1 ? 
ATOM   271  O  OE2 . GLU A  1 36  ? -31.969 -5.795  45.027  1.000 68.729 0 59   GLU A OE2 1 ? 
ATOM   272  N  N   . PRO A  1 37  ? -27.312 -9.455  41.751  1.000 30.820 0 60   PRO A N   1 ? 
ATOM   273  C  CA  . PRO A  1 37  ? -26.721 -10.614 41.078  1.000 30.485 0 60   PRO A CA  1 ? 
ATOM   274  C  C   . PRO A  1 37  ? -27.736 -11.527 40.428  1.000 28.706 0 60   PRO A C   1 ? 
ATOM   275  O  O   . PRO A  1 37  ? -28.848 -11.682 40.938  1.000 27.480 0 60   PRO A O   1 ? 
ATOM   276  C  CB  . PRO A  1 37  ? -25.956 -11.384 42.155  1.000 31.843 0 60   PRO A CB  1 ? 
ATOM   277  C  CG  . PRO A  1 37  ? -25.869 -10.452 43.336  1.000 35.419 0 60   PRO A CG  1 ? 
ATOM   278  C  CD  . PRO A  1 37  ? -26.805 -9.286  43.118  1.000 32.546 0 60   PRO A CD  1 ? 
ATOM   279  N  N   . ASP A  1 38  ? -27.322 -12.149 39.308  1.000 24.121 0 61   ASP A N   1 ? 
ATOM   280  C  CA  . ASP A  1 38  ? -28.199 -13.020 38.543  1.000 24.518 0 61   ASP A CA  1 ? 
ATOM   281  C  C   . ASP A  1 38  ? -27.335 -14.087 37.881  1.000 23.585 0 61   ASP A C   1 ? 
ATOM   282  O  O   . ASP A  1 38  ? -26.101 -14.022 37.935  1.000 25.237 0 61   ASP A O   1 ? 
ATOM   283  C  CB  . ASP A  1 38  ? -29.034 -12.210 37.541  1.000 25.711 0 61   ASP A CB  1 ? 
ATOM   284  C  CG  . ASP A  1 38  ? -28.200 -11.453 36.527  1.000 30.790 0 61   ASP A CG  1 ? 
ATOM   285  O  OD1 . ASP A  1 38  ? -26.932 -11.592 36.537  1.000 30.658 0 61   ASP A OD1 1 ? 
ATOM   286  O  OD2 . ASP A  1 38  ? -28.810 -10.773 35.698  1.000 34.214 0 61   ASP A OD2 1 ? 
ATOM   287  N  N   . TYR A  1 39  ? -27.986 -15.090 37.318  1.000 23.118 0 62   TYR A N   1 ? 
ATOM   288  C  CA  . TYR A  1 39  ? -27.291 -16.135 36.589  1.000 22.156 0 62   TYR A CA  1 ? 
ATOM   289  C  C   . TYR A  1 39  ? -28.237 -16.718 35.547  1.000 24.868 0 62   TYR A C   1 ? 
ATOM   290  O  O   . TYR A  1 39  ? -29.478 -16.595 35.656  1.000 22.942 0 62   TYR A O   1 ? 
ATOM   291  C  CB  . TYR A  1 39  ? -26.779 -17.173 37.598  1.000 22.752 0 62   TYR A CB  1 ? 
ATOM   292  C  CG  . TYR A  1 39  ? -27.833 -17.824 38.485  1.000 23.576 0 62   TYR A CG  1 ? 
ATOM   293  C  CD1 . TYR A  1 39  ? -28.653 -18.830 38.012  1.000 24.293 0 62   TYR A CD1 1 ? 
ATOM   294  C  CD2 . TYR A  1 39  ? -28.004 -17.417 39.808  1.000 26.025 0 62   TYR A CD2 1 ? 
ATOM   295  C  CE1 . TYR A  1 39  ? -29.605 -19.422 38.823  1.000 25.521 0 62   TYR A CE1 1 ? 
ATOM   296  C  CE2 . TYR A  1 39  ? -28.938 -18.017 40.636  1.000 24.838 0 62   TYR A CE2 1 ? 
ATOM   297  C  CZ  . TYR A  1 39  ? -29.758 -19.006 40.135  1.000 26.701 0 62   TYR A CZ  1 ? 
ATOM   298  O  OH  . TYR A  1 39  ? -30.676 -19.609 40.941  1.000 28.060 0 62   TYR A OH  1 ? 
ATOM   299  N  N   . LEU A  1 40  ? -27.621 -17.294 34.512  1.000 22.476 0 63   LEU A N   1 ? 
ATOM   300  C  CA  . LEU A  1 40  ? -28.324 -18.148 33.585  1.000 22.337 0 63   LEU A CA  1 ? 
ATOM   301  C  C   . LEU A  1 40  ? -28.329 -19.566 34.131  1.000 22.555 0 63   LEU A C   1 ? 
ATOM   302  O  O   . LEU A  1 40  ? -27.317 -20.044 34.609  1.000 24.073 0 63   LEU A O   1 ? 
ATOM   303  C  CB  . LEU A  1 40  ? -27.642 -18.083 32.226  1.000 22.563 0 63   LEU A CB  1 ? 
ATOM   304  C  CG  . LEU A  1 40  ? -28.453 -18.694 31.094  1.000 25.309 0 63   LEU A CG  1 ? 
ATOM   305  C  CD1 . LEU A  1 40  ? -29.543 -17.725 30.667  1.000 25.879 0 63   LEU A CD1 1 ? 
ATOM   306  C  CD2 . LEU A  1 40  ? -27.542 -19.047 29.905  1.000 24.693 0 63   LEU A CD2 1 ? 
ATOM   307  N  N   . VAL A  1 41  ? -29.489 -20.229 34.081  1.000 23.844 0 64   VAL A N   1 ? 
ATOM   308  C  CA  . VAL A  1 41  ? -29.592 -21.556 34.654  1.000 24.672 0 64   VAL A CA  1 ? 
ATOM   309  C  C   . VAL A  1 41  ? -30.267 -22.524 33.684  1.000 24.094 0 64   VAL A C   1 ? 
ATOM   310  O  O   . VAL A  1 41  ? -31.192 -22.155 32.974  1.000 26.356 0 64   VAL A O   1 ? 
ATOM   311  C  CB  . VAL A  1 41  ? -30.337 -21.565 36.010  1.000 27.854 0 64   VAL A CB  1 ? 
ATOM   312  C  CG1 . VAL A  1 41  ? -31.748 -21.007 35.895  1.000 28.175 0 64   VAL A CG1 1 ? 
ATOM   313  C  CG2 . VAL A  1 41  ? -30.379 -22.960 36.618  1.000 26.769 0 64   VAL A CG2 1 ? 
ATOM   314  N  N   . SER A  1 42  ? -29.771 -23.765 33.731  1.000 22.054 0 65   SER A N   1 ? 
ATOM   315  C  CA  . SER A  1 42  ? -30.303 -24.927 33.057  1.000 25.605 0 65   SER A CA  1 ? 
ATOM   316  C  C   . SER A  1 42  ? -30.708 -25.929 34.126  1.000 26.783 0 65   SER A C   1 ? 
ATOM   317  O  O   . SER A  1 42  ? -29.942 -26.180 35.043  1.000 26.532 0 65   SER A O   1 ? 
ATOM   318  C  CB  . SER A  1 42  ? -29.314 -25.549 32.125  1.000 27.991 0 65   SER A CB  1 ? 
ATOM   319  O  OG  . SER A  1 42  ? -29.806 -26.759 31.546  1.000 26.540 0 65   SER A OG  1 ? 
ATOM   320  N  N   . ARG A  1 43  ? -31.917 -26.481 33.987  1.000 27.257 0 66   ARG A N   1 ? 
ATOM   321  C  CA  . ARG A  1 43  ? -32.383 -27.507 34.910  1.000 29.151 0 66   ARG A CA  1 ? 
ATOM   322  C  C   . ARG A  1 43  ? -32.494 -28.848 34.192  1.000 33.547 0 66   ARG A C   1 ? 
ATOM   323  O  O   . ARG A  1 43  ? -32.914 -29.828 34.815  1.000 33.750 0 66   ARG A O   1 ? 
ATOM   324  C  CB  . ARG A  1 43  ? -33.731 -27.097 35.514  1.000 34.435 0 66   ARG A CB  1 ? 
ATOM   325  C  CG  . ARG A  1 43  ? -33.678 -25.780 36.265  1.000 39.882 0 66   ARG A CG  1 ? 
ATOM   326  C  CD  . ARG A  1 43  ? -35.070 -25.308 36.686  1.000 52.717 0 66   ARG A CD  1 ? 
ATOM   327  N  NE  . ARG A  1 43  ? -35.029 -23.968 37.266  1.000 56.685 0 66   ARG A NE  1 ? 
ATOM   328  C  CZ  . ARG A  1 43  ? -34.343 -23.640 38.363  1.000 51.903 0 66   ARG A CZ  1 ? 
ATOM   329  N  NH1 . ARG A  1 43  ? -34.108 -22.367 38.643  1.000 39.618 0 66   ARG A NH1 1 ? 
ATOM   330  N  NH2 . ARG A  1 43  ? -33.843 -24.591 39.140  1.000 54.323 0 66   ARG A NH2 1 ? 
ATOM   331  N  N   . ASP A  1 44  ? -32.041 -28.913 32.925  1.000 29.026 0 67   ASP A N   1 ? 
ATOM   332  C  CA  . ASP A  1 44  ? -32.060 -30.167 32.175  1.000 31.028 0 67   ASP A CA  1 ? 
ATOM   333  C  C   . ASP A  1 44  ? -30.651 -30.550 31.719  1.000 32.378 0 67   ASP A C   1 ? 
ATOM   334  O  O   . ASP A  1 44  ? -30.456 -31.013 30.594  1.000 33.335 0 67   ASP A O   1 ? 
ATOM   335  C  CB  . ASP A  1 44  ? -33.031 -30.086 30.996  1.000 28.885 0 67   ASP A CB  1 ? 
ATOM   336  C  CG  . ASP A  1 44  ? -32.831 -28.889 30.096  1.000 33.679 0 67   ASP A CG  1 ? 
ATOM   337  O  OD1 . ASP A  1 44  ? -31.785 -28.199 30.259  1.000 29.117 0 67   ASP A OD1 1 ? 
ATOM   338  O  OD2 . ASP A  1 44  ? -33.743 -28.595 29.300  1.000 33.998 0 67   ASP A OD2 1 ? 
ATOM   339  N  N   . ASN A  1 45  ? -29.670 -30.346 32.605  1.000 28.884 0 68   ASN A N   1 ? 
ATOM   340  C  CA  . ASN A  1 45  ? -28.296 -30.732 32.347  1.000 28.491 0 68   ASN A CA  1 ? 
ATOM   341  C  C   . ASN A  1 45  ? -27.765 -30.135 31.044  1.000 29.275 0 68   ASN A C   1 ? 
ATOM   342  O  O   . ASN A  1 45  ? -27.048 -30.798 30.304  1.000 26.890 0 68   ASN A O   1 ? 
ATOM   343  C  CB  . ASN A  1 45  ? -28.142 -32.246 32.310  1.000 28.353 0 68   ASN A CB  1 ? 
ATOM   344  C  CG  . ASN A  1 45  ? -26.701 -32.662 32.489  1.000 26.920 0 68   ASN A CG  1 ? 
ATOM   345  O  OD1 . ASN A  1 45  ? -25.918 -31.999 33.157  1.000 29.125 0 68   ASN A OD1 1 ? 
ATOM   346  N  ND2 . ASN A  1 45  ? -26.353 -33.794 31.932  1.000 28.403 0 68   ASN A ND2 1 ? 
ATOM   347  N  N   . GLY A  1 46  ? -28.096 -28.862 30.808  1.000 28.619 0 69   GLY A N   1 ? 
ATOM   348  C  CA  . GLY A  1 46  ? -27.382 -28.032 29.847  1.000 31.270 0 69   GLY A CA  1 ? 
ATOM   349  C  C   . GLY A  1 46  ? -28.124 -27.791 28.539  1.000 31.261 0 69   GLY A C   1 ? 
ATOM   350  O  O   . GLY A  1 46  ? -27.613 -27.086 27.661  1.000 31.848 0 69   GLY A O   1 ? 
ATOM   351  N  N   . LYS A  1 47  ? -29.331 -28.357 28.380  1.000 29.951 0 70   LYS A N   1 ? 
ATOM   352  C  CA  . LYS A  1 47  ? -30.052 -28.246 27.120  1.000 31.879 0 70   LYS A CA  1 ? 
ATOM   353  C  C   . LYS A  1 47  ? -30.720 -26.877 26.965  1.000 30.881 0 70   LYS A C   1 ? 
ATOM   354  O  O   . LYS A  1 47  ? -30.596 -26.253 25.908  1.000 30.228 0 70   LYS A O   1 ? 
ATOM   355  C  CB  . LYS A  1 47  ? -31.131 -29.332 27.004  1.000 36.085 0 70   LYS A CB  1 ? 
ATOM   356  C  CG  . LYS A  1 47  ? -30.616 -30.739 26.757  1.000 44.071 0 70   LYS A CG  1 ? 
ATOM   357  C  CD  . LYS A  1 47  ? -29.875 -30.883 25.434  1.000 57.884 0 70   LYS A CD  1 ? 
ATOM   358  C  CE  . LYS A  1 47  ? -30.515 -30.121 24.292  1.000 63.531 0 70   LYS A CE  1 ? 
ATOM   359  N  NZ  . LYS A  1 47  ? -29.927 -30.511 22.990  1.000 66.988 0 70   LYS A NZ  1 ? 
ATOM   360  N  N   . THR A  1 48  ? -31.489 -26.448 27.978  1.000 27.072 0 71   THR A N   1 ? 
ATOM   361  C  CA  . THR A  1 48  ? -32.259 -25.218 27.877  1.000 27.536 0 71   THR A CA  1 ? 
ATOM   362  C  C   . THR A  1 48  ? -31.890 -24.329 29.055  1.000 24.572 0 71   THR A C   1 ? 
ATOM   363  O  O   . THR A  1 48  ? -31.505 -24.847 30.078  1.000 25.403 0 71   THR A O   1 ? 
ATOM   364  C  CB  . THR A  1 48  ? -33.772 -25.487 27.913  1.000 32.755 0 71   THR A CB  1 ? 
ATOM   365  O  OG1 . THR A  1 48  ? -34.103 -26.230 29.089  1.000 32.238 0 71   THR A OG1 1 ? 
ATOM   366  C  CG2 . THR A  1 48  ? -34.227 -26.281 26.708  1.000 37.731 0 71   THR A CG2 1 ? 
ATOM   367  N  N   . TRP A  1 49  ? -32.112 -23.032 28.910  1.000 23.310 0 72   TRP A N   1 ? 
ATOM   368  C  CA  . TRP A  1 49  ? -31.556 -22.033 29.799  1.000 26.897 0 72   TRP A CA  1 ? 
ATOM   369  C  C   . TRP A  1 49  ? -32.496 -20.853 29.967  1.000 25.611 0 72   TRP A C   1 ? 
ATOM   370  O  O   . TRP A  1 49  ? -33.088 -20.414 28.976  1.000 28.831 0 72   TRP A O   1 ? 
ATOM   371  C  CB  . TRP A  1 49  ? -30.231 -21.524 29.195  1.000 27.253 0 72   TRP A CB  1 ? 
ATOM   372  C  CG  . TRP A  1 49  ? -29.199 -22.598 29.038  1.000 26.842 0 72   TRP A CG  1 ? 
ATOM   373  C  CD1 . TRP A  1 49  ? -29.088 -23.505 28.020  1.000 28.113 0 72   TRP A CD1 1 ? 
ATOM   374  C  CD2 . TRP A  1 49  ? -28.106 -22.860 29.933  1.000 26.005 0 72   TRP A CD2 1 ? 
ATOM   375  N  NE1 . TRP A  1 49  ? -28.032 -24.343 28.247  1.000 25.528 0 72   TRP A NE1 1 ? 
ATOM   376  C  CE2 . TRP A  1 49  ? -27.412 -23.977 29.411  1.000 25.309 0 72   TRP A CE2 1 ? 
ATOM   377  C  CE3 . TRP A  1 49  ? -27.675 -22.296 31.136  1.000 26.706 0 72   TRP A CE3 1 ? 
ATOM   378  C  CZ2 . TRP A  1 49  ? -26.285 -24.505 30.023  1.000 24.857 0 72   TRP A CZ2 1 ? 
ATOM   379  C  CZ3 . TRP A  1 49  ? -26.579 -22.849 31.762  1.000 25.643 0 72   TRP A CZ3 1 ? 
ATOM   380  C  CH2 . TRP A  1 49  ? -25.870 -23.914 31.196  1.000 25.831 0 72   TRP A CH2 1 ? 
ATOM   381  N  N   . GLU A  1 50  ? -32.498 -20.232 31.161  1.000 26.344 0 73   GLU A N   1 ? 
ATOM   382  C  CA  . GLU A  1 50  ? -33.153 -18.936 31.346  1.000 27.587 0 73   GLU A CA  1 ? 
ATOM   383  C  C   . GLU A  1 50  ? -32.449 -18.154 32.449  1.000 24.941 0 73   GLU A C   1 ? 
ATOM   384  O  O   . GLU A  1 50  ? -31.767 -18.738 33.278  1.000 25.122 0 73   GLU A O   1 ? 
ATOM   385  C  CB  . GLU A  1 50  ? -34.647 -19.137 31.683  1.000 29.856 0 73   GLU A CB  1 ? 
ATOM   386  C  CG  . GLU A  1 50  ? -34.884 -19.888 32.985  1.000 29.991 0 73   GLU A CG  1 ? 
ATOM   387  C  CD  . GLU A  1 50  ? -36.332 -20.125 33.428  1.000 40.165 0 73   GLU A CD  1 ? 
ATOM   388  O  OE1 . GLU A  1 50  ? -36.536 -20.987 34.294  1.000 43.185 0 73   GLU A OE1 1 ? 
ATOM   389  O  OE2 . GLU A  1 50  ? -37.234 -19.420 32.959  1.000 38.386 0 73   GLU A OE2 1 ? 
ATOM   390  N  N   . MET A  1 51  ? -32.689 -16.846 32.508  1.000 23.704 0 74   MET A N   1 ? 
ATOM   391  C  CA  . MET A  1 51  ? -32.106 -16.013 33.545  1.000 24.318 0 74   MET A CA  1 ? 
ATOM   392  C  C   . MET A  1 51  ? -32.919 -16.119 34.837  1.000 29.484 0 74   MET A C   1 ? 
ATOM   393  O  O   . MET A  1 51  ? -34.134 -16.301 34.804  1.000 24.850 0 74   MET A O   1 ? 
ATOM   394  C  CB  . MET A  1 51  ? -32.032 -14.548 33.097  1.000 28.127 0 74   MET A CB  1 ? 
ATOM   395  C  CG  . MET A  1 51  ? -31.055 -14.288 31.981  1.000 28.781 0 74   MET A CG  1 ? 
ATOM   396  S  SD  . MET A  1 51  ? -29.310 -14.630 32.444  1.000 28.210 0 74   MET A SD  1 ? 
ATOM   397  C  CE  . MET A  1 51  ? -29.012 -13.391 33.712  1.000 27.799 0 74   MET A CE  1 ? 
ATOM   398  N  N   . LYS A  1 52  ? -32.223 -15.966 35.967  1.000 26.381 0 75   LYS A N   1 ? 
ATOM   399  C  CA  . LYS A  1 52  ? -32.815 -16.000 37.287  1.000 28.623 0 75   LYS A CA  1 ? 
ATOM   400  C  C   . LYS A  1 52  ? -32.020 -15.102 38.222  1.000 31.166 0 75   LYS A C   1 ? 
ATOM   401  O  O   . LYS A  1 52  ? -30.774 -15.070 38.167  1.000 26.782 0 75   LYS A O   1 ? 
ATOM   402  C  CB  . LYS A  1 52  ? -32.814 -17.448 37.754  1.000 31.438 0 75   LYS A CB  1 ? 
ATOM   403  C  CG  . LYS A  1 52  ? -33.502 -17.692 39.081  1.000 40.062 0 75   LYS A CG  1 ? 
ATOM   404  C  CD  . LYS A  1 52  ? -33.484 -19.149 39.461  1.000 48.073 0 75   LYS A CD  1 ? 
ATOM   405  C  CE  . LYS A  1 52  ? -33.798 -19.375 40.927  1.000 51.707 0 75   LYS A CE  1 ? 
ATOM   406  N  NZ  . LYS A  1 52  ? -35.206 -19.023 41.206  1.000 54.782 0 75   LYS A NZ  1 ? 
ATOM   407  N  N   . ALA A  1 53  ? -32.749 -14.392 39.097  1.000 30.797 0 76   ALA A N   1 ? 
ATOM   408  C  CA  . ALA A  1 53  ? -32.121 -13.575 40.125  1.000 31.040 0 76   ALA A CA  1 ? 
ATOM   409  C  C   . ALA A  1 53  ? -31.489 -14.495 41.174  1.000 29.964 0 76   ALA A C   1 ? 
ATOM   410  O  O   . ALA A  1 53  ? -32.081 -15.485 41.579  1.000 26.597 0 76   ALA A O   1 ? 
ATOM   411  C  CB  . ALA A  1 53  ? -33.142 -12.636 40.761  1.000 31.826 0 76   ALA A CB  1 ? 
ATOM   412  N  N   . ALA A  1 54  ? -30.276 -14.137 41.638  1.000 25.537 0 77   ALA A N   1 ? 
ATOM   413  C  CA  . ALA A  1 54  ? -29.676 -14.809 42.767  1.000 27.110 0 77   ALA A CA  1 ? 
ATOM   414  C  C   . ALA A  1 54  ? -30.355 -14.340 44.063  1.000 27.323 0 77   ALA A C   1 ? 
ATOM   415  O  O   . ALA A  1 54  ? -30.840 -13.209 44.169  1.000 25.358 0 77   ALA A O   1 ? 
ATOM   416  C  CB  . ALA A  1 54  ? -28.186 -14.518 42.796  1.000 27.863 0 77   ALA A CB  1 ? 
ATOM   417  N  N   . PRO A  1 55  ? -30.358 -15.173 45.122  1.000 28.977 0 78   PRO A N   1 ? 
ATOM   418  C  CA  . PRO A  1 55  ? -30.934 -14.739 46.398  1.000 30.639 0 78   PRO A CA  1 ? 
ATOM   419  C  C   . PRO A  1 55  ? -30.102 -13.608 47.004  1.000 32.023 0 78   PRO A C   1 ? 
ATOM   420  O  O   . PRO A  1 55  ? -28.925 -13.417 46.656  1.000 29.213 0 78   PRO A O   1 ? 
ATOM   421  C  CB  . PRO A  1 55  ? -30.921 -15.997 47.273  1.000 31.817 0 78   PRO A CB  1 ? 
ATOM   422  C  CG  . PRO A  1 55  ? -30.033 -17.016 46.560  1.000 32.084 0 78   PRO A CG  1 ? 
ATOM   423  C  CD  . PRO A  1 55  ? -29.788 -16.524 45.148  1.000 28.180 0 78   PRO A CD  1 ? 
ATOM   424  N  N   . ALA A  1 56  ? -30.687 -12.912 47.991  1.000 32.571 0 79   ALA A N   1 ? 
ATOM   425  C  CA  . ALA A  1 56  ? -30.055 -11.753 48.606  1.000 29.161 0 79   ALA A CA  1 ? 
ATOM   426  C  C   . ALA A  1 56  ? -28.793 -12.123 49.396  1.000 29.992 0 79   ALA A C   1 ? 
ATOM   427  O  O   . ALA A  1 56  ? -27.981 -11.235 49.630  1.000 29.581 0 79   ALA A O   1 ? 
ATOM   428  C  CB  . ALA A  1 56  ? -31.064 -11.011 49.470  1.000 34.093 0 79   ALA A CB  1 ? 
ATOM   429  N  N   . GLY A  1 57  ? -28.659 -13.390 49.850  1.000 25.583 0 80   GLY A N   1 ? 
ATOM   430  C  CA  . GLY A  1 57  ? -27.476 -13.844 50.567  1.000 27.331 0 80   GLY A CA  1 ? 
ATOM   431  C  C   . GLY A  1 57  ? -26.232 -14.048 49.675  1.000 27.431 0 80   GLY A C   1 ? 
ATOM   432  O  O   . GLY A  1 57  ? -25.110 -14.165 50.166  1.000 28.154 0 80   GLY A O   1 ? 
ATOM   433  N  N   . TYR A  1 58  ? -26.417 -14.071 48.352  1.000 27.799 0 81   TYR A N   1 ? 
ATOM   434  C  CA  . TYR A  1 58  ? -25.331 -14.228 47.409  1.000 25.556 0 81   TYR A CA  1 ? 
ATOM   435  C  C   . TYR A  1 58  ? -24.764 -12.847 47.141  1.000 25.535 0 81   TYR A C   1 ? 
ATOM   436  O  O   . TYR A  1 58  ? -25.511 -11.940 46.785  1.000 23.462 0 81   TYR A O   1 ? 
ATOM   437  C  CB  . TYR A  1 58  ? -25.824 -14.850 46.098  1.000 25.201 0 81   TYR A CB  1 ? 
ATOM   438  C  CG  . TYR A  1 58  ? -24.710 -14.936 45.064  1.000 23.712 0 81   TYR A CG  1 ? 
ATOM   439  C  CD1 . TYR A  1 58  ? -23.791 -15.980 45.050  1.000 26.422 0 81   TYR A CD1 1 ? 
ATOM   440  C  CD2 . TYR A  1 58  ? -24.560 -13.929 44.123  1.000 25.316 0 81   TYR A CD2 1 ? 
ATOM   441  C  CE1 . TYR A  1 58  ? -22.750 -16.011 44.134  1.000 22.693 0 81   TYR A CE1 1 ? 
ATOM   442  C  CE2 . TYR A  1 58  ? -23.536 -13.959 43.195  1.000 24.301 0 81   TYR A CE2 1 ? 
ATOM   443  C  CZ  . TYR A  1 58  ? -22.615 -14.987 43.213  1.000 23.363 0 81   TYR A CZ  1 ? 
ATOM   444  O  OH  . TYR A  1 58  ? -21.629 -14.916 42.271  1.000 23.764 0 81   TYR A OH  1 ? 
ATOM   445  N  N   . PRO A  1 59  ? -23.454 -12.616 47.388  1.000 22.721 0 82   PRO A N   1 ? 
ATOM   446  C  CA  . PRO A  1 59  ? -22.944 -11.257 47.443  1.000 20.987 0 82   PRO A CA  1 ? 
ATOM   447  C  C   . PRO A  1 59  ? -22.907 -10.574 46.086  1.000 21.037 0 82   PRO A C   1 ? 
ATOM   448  O  O   . PRO A  1 59  ? -22.710 -11.204 45.060  1.000 24.400 0 82   PRO A O   1 ? 
ATOM   449  C  CB  . PRO A  1 59  ? -21.507 -11.404 48.014  1.000 23.703 0 82   PRO A CB  1 ? 
ATOM   450  C  CG  . PRO A  1 59  ? -21.162 -12.874 47.855  1.000 23.573 0 82   PRO A CG  1 ? 
ATOM   451  C  CD  . PRO A  1 59  ? -22.478 -13.627 47.837  1.000 23.628 0 82   PRO A CD  1 ? 
ATOM   452  N  N   . PRO A  1 60  ? -23.080 -9.250  46.038  1.000 23.056 0 83   PRO A N   1 ? 
ATOM   453  C  CA  . PRO A  1 60  ? -22.922 -8.535  44.776  1.000 24.302 0 83   PRO A CA  1 ? 
ATOM   454  C  C   . PRO A  1 60  ? -21.480 -8.612  44.317  1.000 20.006 0 83   PRO A C   1 ? 
ATOM   455  O  O   . PRO A  1 60  ? -20.597 -9.013  45.075  1.000 19.413 0 83   PRO A O   1 ? 
ATOM   456  C  CB  . PRO A  1 60  ? -23.287 -7.093  45.082  1.000 25.391 0 83   PRO A CB  1 ? 
ATOM   457  C  CG  . PRO A  1 60  ? -23.253 -6.997  46.557  1.000 25.977 0 83   PRO A CG  1 ? 
ATOM   458  C  CD  . PRO A  1 60  ? -23.428 -8.377  47.156  1.000 24.798 0 83   PRO A CD  1 ? 
ATOM   459  N  N   . ASN A  1 61  ? -21.291 -8.221  43.073  1.000 21.167 0 84   ASN A N   1 ? 
ATOM   460  C  CA  . ASN A  1 61  ? -19.949 -8.127  42.518  1.000 21.891 0 84   ASN A CA  1 ? 
ATOM   461  C  C   . ASN A  1 61  ? -19.313 -6.835  43.003  1.000 22.035 0 84   ASN A C   1 ? 
ATOM   462  O  O   . ASN A  1 61  ? -19.429 -5.837  42.322  1.000 25.195 0 84   ASN A O   1 ? 
ATOM   463  C  CB  . ASN A  1 61  ? -19.982 -8.190  40.999  1.000 20.502 0 84   ASN A CB  1 ? 
ATOM   464  C  CG  . ASN A  1 61  ? -20.389 -9.549  40.483  1.000 20.186 0 84   ASN A CG  1 ? 
ATOM   465  O  OD1 . ASN A  1 61  ? -19.975 -10.581 41.026  1.000 20.542 0 84   ASN A OD1 1 ? 
ATOM   466  N  ND2 . ASN A  1 61  ? -21.291 -9.559  39.517  1.000 22.094 0 84   ASN A ND2 1 ? 
ATOM   467  N  N   . TYR A  1 62  ? -18.600 -6.879  44.137  1.000 22.445 0 85   TYR A N   1 ? 
ATOM   468  C  CA  . TYR A  1 62  ? -17.934 -5.701  44.689  1.000 22.704 0 85   TYR A CA  1 ? 
ATOM   469  C  C   . TYR A  1 62  ? -16.707 -5.390  43.845  1.000 25.404 0 85   TYR A C   1 ? 
ATOM   470  O  O   . TYR A  1 62  ? -16.472 -4.243  43.483  1.000 24.727 0 85   TYR A O   1 ? 
ATOM   471  C  CB  . TYR A  1 62  ? -17.501 -5.880  46.145  1.000 23.822 0 85   TYR A CB  1 ? 
ATOM   472  C  CG  . TYR A  1 62  ? -18.692 -5.937  47.094  1.000 21.268 0 85   TYR A CG  1 ? 
ATOM   473  C  CD1 . TYR A  1 62  ? -19.430 -4.786  47.372  1.000 22.140 0 85   TYR A CD1 1 ? 
ATOM   474  C  CD2 . TYR A  1 62  ? -19.105 -7.120  47.671  1.000 21.296 0 85   TYR A CD2 1 ? 
ATOM   475  C  CE1 . TYR A  1 62  ? -20.566 -4.833  48.166  1.000 22.356 0 85   TYR A CE1 1 ? 
ATOM   476  C  CE2 . TYR A  1 62  ? -20.212 -7.173  48.502  1.000 20.122 0 85   TYR A CE2 1 ? 
ATOM   477  C  CZ  . TYR A  1 62  ? -20.930 -6.017  48.776  1.000 22.203 0 85   TYR A CZ  1 ? 
ATOM   478  O  OH  . TYR A  1 62  ? -22.012 -6.085  49.612  1.000 20.026 0 85   TYR A OH  1 ? 
ATOM   479  N  N   . GLY A  1 63  ? -15.992 -6.437  43.429  1.000 23.800 0 86   GLY A N   1 ? 
ATOM   480  C  CA  . GLY A  1 63  ? -14.964 -6.282  42.421  1.000 21.922 0 86   GLY A CA  1 ? 
ATOM   481  C  C   . GLY A  1 63  ? -15.464 -6.722  41.046  1.000 21.070 0 86   GLY A C   1 ? 
ATOM   482  O  O   . GLY A  1 63  ? -16.669 -6.825  40.782  1.000 22.133 0 86   GLY A O   1 ? 
ATOM   483  N  N   . GLY A  1 64  ? -14.499 -7.018  40.177  1.000 19.847 0 87   GLY A N   1 ? 
ATOM   484  C  CA  . GLY A  1 64  ? -14.800 -7.510  38.858  1.000 19.544 0 87   GLY A CA  1 ? 
ATOM   485  C  C   . GLY A  1 64  ? -15.270 -6.365  37.982  1.000 20.528 0 87   GLY A C   1 ? 
ATOM   486  O  O   . GLY A  1 64  ? -15.018 -5.209  38.302  1.000 21.829 0 87   GLY A O   1 ? 
ATOM   487  N  N   . ILE A  1 65  ? -15.823 -6.726  36.844  1.000 20.837 0 88   ILE A N   1 ? 
ATOM   488  C  CA  . ILE A  1 65  ? -16.156 -5.785  35.798  1.000 21.501 0 88   ILE A CA  1 ? 
ATOM   489  C  C   . ILE A  1 65  ? -17.470 -6.242  35.187  1.000 20.204 0 88   ILE A C   1 ? 
ATOM   490  O  O   . ILE A  1 65  ? -17.821 -7.418  35.271  1.000 21.093 0 88   ILE A O   1 ? 
ATOM   491  C  CB  . ILE A  1 65  ? -15.037 -5.703  34.757  1.000 21.540 0 88   ILE A CB  1 ? 
ATOM   492  C  CG1 . ILE A  1 65  ? -14.801 -7.070  34.109  1.000 23.553 0 88   ILE A CG1 1 ? 
ATOM   493  C  CG2 . ILE A  1 65  ? -13.787 -5.152  35.382  1.000 22.184 0 88   ILE A CG2 1 ? 
ATOM   494  C  CD1 . ILE A  1 65  ? -13.718 -7.081  33.081  1.000 25.336 0 88   ILE A CD1 1 ? 
ATOM   495  N  N   . PRO A  1 66  ? -18.215 -5.353  34.514  1.000 20.145 0 89   PRO A N   1 ? 
ATOM   496  C  CA  . PRO A  1 66  ? -19.517 -5.758  33.986  1.000 21.802 0 89   PRO A CA  1 ? 
ATOM   497  C  C   . PRO A  1 66  ? -19.532 -6.967  33.049  1.000 19.190 0 89   PRO A C   1 ? 
ATOM   498  O  O   . PRO A  1 66  ? -20.503 -7.693  33.034  1.000 22.689 0 89   PRO A O   1 ? 
ATOM   499  C  CB  . PRO A  1 66  ? -19.995 -4.470  33.292  1.000 22.921 0 89   PRO A CB  1 ? 
ATOM   500  C  CG  . PRO A  1 66  ? -19.404 -3.378  34.154  1.000 25.987 0 89   PRO A CG  1 ? 
ATOM   501  C  CD  . PRO A  1 66  ? -18.023 -3.889  34.504  1.000 23.658 0 89   PRO A CD  1 ? 
ATOM   502  N  N   . LYS A  1 67  ? -18.489 -7.158  32.231  1.000 19.562 0 90   LYS A N   1 ? 
ATOM   503  C  CA  . LYS A  1 67  ? -18.534 -8.166  31.175  1.000 21.904 0 90   LYS A CA  1 ? 
ATOM   504  C  C   . LYS A  1 67  ? -18.058 -9.533  31.639  1.000 18.987 0 90   LYS A C   1 ? 
ATOM   505  O  O   . LYS A  1 67  ? -18.093 -10.480 30.838  1.000 20.001 0 90   LYS A O   1 ? 
ATOM   506  C  CB  . LYS A  1 67  ? -17.686 -7.775  29.971  1.000 25.490 0 90   LYS A CB  1 ? 
ATOM   507  C  CG  . LYS A  1 67  ? -16.187 -7.779  30.249  1.000 25.228 0 90   LYS A CG  1 ? 
ATOM   508  C  CD  . LYS A  1 67  ? -15.364 -7.263  29.081  1.000 31.135 0 90   LYS A CD  1 ? 
ATOM   509  C  CE  . LYS A  1 67  ? -13.955 -6.910  29.497  1.000 35.391 0 90   LYS A CE  1 ? 
ATOM   510  N  NZ  . LYS A  1 67  ? -13.129 -6.475  28.340  1.000 42.581 0 90   LYS A NZ  1 ? 
ATOM   511  N  N   . GLU A  1 68  ? -17.533 -9.638  32.864  1.000 18.973 0 91   GLU A N   1 ? 
ATOM   512  C  CA  . GLU A  1 68  ? -16.999 -10.920 33.327  1.000 20.690 0 91   GLU A CA  1 ? 
ATOM   513  C  C   . GLU A  1 68  ? -17.582 -11.304 34.684  1.000 19.583 0 91   GLU A C   1 ? 
ATOM   514  O  O   . GLU A  1 68  ? -17.625 -10.490 35.606  1.000 22.861 0 91   GLU A O   1 ? 
ATOM   515  C  CB  . GLU A  1 68  ? -15.469 -10.896 33.409  1.000 19.565 0 91   GLU A CB  1 ? 
ATOM   516  C  CG  . GLU A  1 68  ? -14.782 -10.942 32.048  1.000 24.435 0 91   GLU A CG  1 ? 
ATOM   517  C  CD  . GLU A  1 68  ? -13.296 -10.613 32.031  1.000 26.903 0 91   GLU A CD  1 ? 
ATOM   518  O  OE1 . GLU A  1 68  ? -12.748 -10.281 33.128  1.000 26.815 0 91   GLU A OE1 1 ? 
ATOM   519  O  OE2 . GLU A  1 68  ? -12.693 -10.582 30.915  1.000 27.069 0 91   GLU A OE2 1 ? 
ATOM   520  N  N   . SER A  1 69  ? -17.983 -12.579 34.805  1.000 19.243 0 92   SER A N   1 ? 
ATOM   521  C  CA  . SER A  1 69  ? -18.401 -13.170 36.062  1.000 18.639 0 92   SER A CA  1 ? 
ATOM   522  C  C   . SER A  1 69  ? -17.186 -13.387 36.956  1.000 20.763 0 92   SER A C   1 ? 
ATOM   523  O  O   . SER A  1 69  ? -16.072 -13.615 36.474  1.000 20.720 0 92   SER A O   1 ? 
ATOM   524  C  CB  . SER A  1 69  ? -19.082 -14.487 35.822  1.000 20.373 0 92   SER A CB  1 ? 
ATOM   525  O  OG  . SER A  1 69  ? -19.515 -15.102 37.028  1.000 21.284 0 92   SER A OG  1 ? 
ATOM   526  N  N   . PRO A  1 70  ? -17.374 -13.420 38.284  1.000 20.499 0 93   PRO A N   1 ? 
ATOM   527  C  CA  . PRO A  1 70  ? -16.375 -14.050 39.154  1.000 19.390 0 93   PRO A CA  1 ? 
ATOM   528  C  C   . PRO A  1 70  ? -16.260 -15.532 38.827  1.000 19.913 0 93   PRO A C   1 ? 
ATOM   529  O  O   . PRO A  1 70  ? -17.198 -16.134 38.277  1.000 18.585 0 93   PRO A O   1 ? 
ATOM   530  C  CB  . PRO A  1 70  ? -16.930 -13.797 40.562  1.000 19.851 0 93   PRO A CB  1 ? 
ATOM   531  C  CG  . PRO A  1 70  ? -18.422 -13.677 40.354  1.000 20.069 0 93   PRO A CG  1 ? 
ATOM   532  C  CD  . PRO A  1 70  ? -18.539 -12.937 39.035  1.000 20.293 0 93   PRO A CD  1 ? 
ATOM   533  N  N   . ALA A  1 71  ? -15.077 -16.088 39.144  1.000 17.718 0 94   ALA A N   1 ? 
ATOM   534  C  CA  . ALA A  1 71  ? -14.869 -17.521 39.115  1.000 18.191 0 94   ALA A CA  1 ? 
ATOM   535  C  C   . ALA A  1 71  ? -15.470 -18.138 40.356  1.000 18.142 0 94   ALA A C   1 ? 
ATOM   536  O  O   . ALA A  1 71  ? -15.321 -17.584 41.430  1.000 20.280 0 94   ALA A O   1 ? 
ATOM   537  C  CB  . ALA A  1 71  ? -13.403 -17.815 39.034  1.000 18.481 0 94   ALA A CB  1 ? 
ATOM   538  N  N   . ILE A  1 72  ? -16.091 -19.316 40.184  1.000 19.965 0 95   ILE A N   1 ? 
ATOM   539  C  CA  . ILE A  1 72  ? -16.796 -20.024 41.247  1.000 19.626 0 95   ILE A CA  1 ? 
ATOM   540  C  C   . ILE A  1 72  ? -16.392 -21.479 41.109  1.000 20.070 0 95   ILE A C   1 ? 
ATOM   541  O  O   . ILE A  1 72  ? -16.585 -22.046 40.025  1.000 20.198 0 95   ILE A O   1 ? 
ATOM   542  C  CB  . ILE A  1 72  ? -18.327 -19.871 41.152  1.000 19.433 0 95   ILE A CB  1 ? 
ATOM   543  C  CG1 . ILE A  1 72  ? -18.766 -18.409 41.355  1.000 20.727 0 95   ILE A CG1 1 ? 
ATOM   544  C  CG2 . ILE A  1 72  ? -19.002 -20.801 42.139  1.000 22.195 0 95   ILE A CG2 1 ? 
ATOM   545  C  CD1 . ILE A  1 72  ? -20.189 -18.119 40.941  1.000 21.309 0 95   ILE A CD1 1 ? 
ATOM   546  N  N   . VAL A  1 73  ? -15.826 -22.022 42.191  1.000 20.478 0 96   VAL A N   1 ? 
ATOM   547  C  CA  . VAL A  1 73  ? -15.190 -23.328 42.163  1.000 20.554 0 96   VAL A CA  1 ? 
ATOM   548  C  C   . VAL A  1 73  ? -15.569 -24.072 43.426  1.000 23.096 0 96   VAL A C   1 ? 
ATOM   549  O  O   . VAL A  1 73  ? -15.591 -23.495 44.510  1.000 22.094 0 96   VAL A O   1 ? 
ATOM   550  C  CB  . VAL A  1 73  ? -13.663 -23.184 42.046  1.000 21.046 0 96   VAL A CB  1 ? 
ATOM   551  C  CG1 . VAL A  1 73  ? -12.956 -24.554 42.017  1.000 21.932 0 96   VAL A CG1 1 ? 
ATOM   552  C  CG2 . VAL A  1 73  ? -13.292 -22.354 40.814  1.000 20.808 0 96   VAL A CG2 1 ? 
ATOM   553  N  N   . ARG A  1 74  ? -15.906 -25.354 43.248  1.000 22.235 0 97   ARG A N   1 ? 
ATOM   554  C  CA  . ARG A  1 74  ? -16.295 -26.194 44.361  1.000 21.162 0 97   ARG A CA  1 ? 
ATOM   555  C  C   . ARG A  1 74  ? -15.053 -26.807 45.014  1.000 22.180 0 97   ARG A C   1 ? 
ATOM   556  O  O   . ARG A  1 74  ? -14.194 -27.378 44.370  1.000 22.301 0 97   ARG A O   1 ? 
ATOM   557  C  CB  . ARG A  1 74  ? -17.288 -27.271 43.916  1.000 24.840 0 97   ARG A CB  1 ? 
ATOM   558  C  CG  . ARG A  1 74  ? -17.826 -28.083 45.092  1.000 26.920 0 97   ARG A CG  1 ? 
ATOM   559  C  CD  . ARG A  1 74  ? -18.721 -29.228 44.721  1.000 30.309 0 97   ARG A CD  1 ? 
ATOM   560  N  NE  . ARG A  1 74  ? -19.906 -28.810 44.009  1.000 31.398 0 97   ARG A NE  1 ? 
ATOM   561  C  CZ  . ARG A  1 74  ? -21.139 -28.724 44.511  1.000 32.118 0 97   ARG A CZ  1 ? 
ATOM   562  N  NH1 . ARG A  1 74  ? -21.335 -28.549 45.805  1.000 34.831 0 97   ARG A NH1 1 ? 
ATOM   563  N  NH2 . ARG A  1 74  ? -22.165 -28.683 43.687  1.000 31.401 0 97   ARG A NH2 1 ? 
ATOM   564  N  N   . ASN A  1 75  ? -14.989 -26.672 46.333  1.000 22.641 0 98   ASN A N   1 ? 
ATOM   565  C  CA  . ASN A  1 75  ? -14.007 -27.329 47.165  1.000 23.385 0 98   ASN A CA  1 ? 
ATOM   566  C  C   . ASN A  1 75  ? -14.391 -28.807 47.241  1.000 26.371 0 98   ASN A C   1 ? 
ATOM   567  O  O   . ASN A  1 75  ? -15.497 -29.111 47.659  1.000 25.450 0 98   ASN A O   1 ? 
ATOM   568  C  CB  . ASN A  1 75  ? -13.989 -26.667 48.543  1.000 25.159 0 98   ASN A CB  1 ? 
ATOM   569  C  CG  . ASN A  1 75  ? -13.040 -27.351 49.507  1.000 25.317 0 98   ASN A CG  1 ? 
ATOM   570  O  OD1 . ASN A  1 75  ? -12.906 -28.585 49.494  1.000 26.299 0 98   ASN A OD1 1 ? 
ATOM   571  N  ND2 . ASN A  1 75  ? -12.397 -26.560 50.342  1.000 25.288 0 98   ASN A ND2 1 ? 
ATOM   572  N  N   . PRO A  1 76  ? -13.538 -29.745 46.808  1.000 24.940 0 99   PRO A N   1 ? 
ATOM   573  C  CA  . PRO A  1 76  ? -13.955 -31.151 46.683  1.000 27.120 0 99   PRO A CA  1 ? 
ATOM   574  C  C   . PRO A  1 76  ? -14.100 -31.868 48.028  1.000 25.797 0 99   PRO A C   1 ? 
ATOM   575  O  O   . PRO A  1 76  ? -14.798 -32.867 48.091  1.000 28.745 0 99   PRO A O   1 ? 
ATOM   576  C  CB  . PRO A  1 76  ? -12.889 -31.797 45.790  1.000 27.329 0 99   PRO A CB  1 ? 
ATOM   577  C  CG  . PRO A  1 76  ? -11.694 -30.892 45.905  1.000 28.210 0 99   PRO A CG  1 ? 
ATOM   578  C  CD  . PRO A  1 76  ? -12.200 -29.493 46.258  1.000 28.209 0 99   PRO A CD  1 ? 
ATOM   579  N  N   . LEU A  1 77  ? -13.458 -31.350 49.078  1.000 25.817 0 100  LEU A N   1 ? 
ATOM   580  C  CA  . LEU A  1 77  ? -13.519 -31.938 50.408  1.000 28.125 0 100  LEU A CA  1 ? 
ATOM   581  C  C   . LEU A  1 77  ? -14.755 -31.424 51.153  1.000 33.196 0 100  LEU A C   1 ? 
ATOM   582  O  O   . LEU A  1 77  ? -15.545 -32.232 51.616  1.000 35.056 0 100  LEU A O   1 ? 
ATOM   583  C  CB  . LEU A  1 77  ? -12.224 -31.627 51.145  1.000 30.305 0 100  LEU A CB  1 ? 
ATOM   584  C  CG  . LEU A  1 77  ? -10.952 -32.132 50.463  1.000 29.809 0 100  LEU A CG  1 ? 
ATOM   585  C  CD1 . LEU A  1 77  ? -9.726  -31.884 51.330  1.000 30.585 0 100  LEU A CD1 1 ? 
ATOM   586  C  CD2 . LEU A  1 77  ? -11.084 -33.610 50.105  1.000 34.180 0 100  LEU A CD2 1 ? 
ATOM   587  N  N   . THR A  1 78  ? -14.981 -30.103 51.182  1.000 26.802 0 101  THR A N   1 ? 
ATOM   588  C  CA  . THR A  1 78  ? -16.112 -29.541 51.908  1.000 27.868 0 101  THR A CA  1 ? 
ATOM   589  C  C   . THR A  1 78  ? -17.391 -29.504 51.065  1.000 27.021 0 101  THR A C   1 ? 
ATOM   590  O  O   . THR A  1 78  ? -18.504 -29.397 51.603  1.000 27.105 0 101  THR A O   1 ? 
ATOM   591  C  CB  . THR A  1 78  ? -15.736 -28.132 52.388  1.000 29.098 0 101  THR A CB  1 ? 
ATOM   592  O  OG1 . THR A  1 78  ? -15.680 -27.291 51.221  1.000 26.334 0 101  THR A OG1 1 ? 
ATOM   593  C  CG2 . THR A  1 78  ? -14.440 -28.108 53.168  1.000 27.045 0 101  THR A CG2 1 ? 
ATOM   594  N  N   . ARG A  1 79  ? -17.253 -29.547 49.732  1.000 24.181 0 102  ARG A N   1 ? 
ATOM   595  C  CA  . ARG A  1 79  ? -18.336 -29.346 48.781  1.000 26.515 0 102  ARG A CA  1 ? 
ATOM   596  C  C   . ARG A  1 79  ? -18.931 -27.932 48.847  1.000 24.731 0 102  ARG A C   1 ? 
ATOM   597  O  O   . ARG A  1 79  ? -19.920 -27.687 48.173  1.000 25.938 0 102  ARG A O   1 ? 
ATOM   598  C  CB  . ARG A  1 79  ? -19.394 -30.442 48.913  1.000 32.264 0 102  ARG A CB  1 ? 
ATOM   599  C  CG  . ARG A  1 79  ? -18.793 -31.840 48.860  1.000 40.901 0 102  ARG A CG  1 ? 
ATOM   600  C  CD  . ARG A  1 79  ? -19.665 -32.845 48.142  1.000 48.120 0 102  ARG A CD  1 ? 
ATOM   601  N  NE  . ARG A  1 79  ? -19.347 -32.793 46.729  1.000 53.379 0 102  ARG A NE  1 ? 
ATOM   602  C  CZ  . ARG A  1 79  ? -20.194 -32.417 45.793  1.000 51.480 0 102  ARG A CZ  1 ? 
ATOM   603  N  NH1 . ARG A  1 79  ? -21.415 -32.062 46.142  1.000 51.248 0 102  ARG A NH1 1 ? 
ATOM   604  N  NH2 . ARG A  1 79  ? -19.820 -32.421 44.525  1.000 56.215 0 102  ARG A NH2 1 ? 
ATOM   605  N  N   . GLU A  1 80  ? -18.327 -27.017 49.617  1.000 23.708 0 103  GLU A N   1 ? 
ATOM   606  C  CA  . GLU A  1 80  ? -18.651 -25.594 49.542  1.000 23.533 0 103  GLU A CA  1 ? 
ATOM   607  C  C   . GLU A  1 80  ? -17.880 -24.947 48.377  1.000 25.394 0 103  GLU A C   1 ? 
ATOM   608  O  O   . GLU A  1 80  ? -17.127 -25.623 47.692  1.000 27.067 0 103  GLU A O   1 ? 
ATOM   609  C  CB  . GLU A  1 80  ? -18.307 -24.905 50.859  1.000 26.375 0 103  GLU A CB  1 ? 
ATOM   610  C  CG  . GLU A  1 80  ? -19.101 -25.398 52.057  1.000 26.241 0 103  GLU A CG  1 ? 
ATOM   611  C  CD  . GLU A  1 80  ? -20.596 -25.159 51.963  1.000 28.384 0 103  GLU A CD  1 ? 
ATOM   612  O  OE1 . GLU A  1 80  ? -21.046 -24.415 51.074  1.000 27.242 0 103  GLU A OE1 1 ? 
ATOM   613  O  OE2 . GLU A  1 80  ? -21.337 -25.714 52.802  1.000 30.983 0 103  GLU A OE2 1 ? 
ATOM   614  N  N   . PHE A  1 81  ? -18.077 -23.639 48.167  1.000 22.707 0 104  PHE A N   1 ? 
ATOM   615  C  CA  . PHE A  1 81  ? -17.571 -22.933 47.009  1.000 19.654 0 104  PHE A CA  1 ? 
ATOM   616  C  C   . PHE A  1 81  ? -16.667 -21.794 47.450  1.000 22.507 0 104  PHE A C   1 ? 
ATOM   617  O  O   . PHE A  1 81  ? -16.888 -21.197 48.528  1.000 22.116 0 104  PHE A O   1 ? 
ATOM   618  C  CB  . PHE A  1 81  ? -18.727 -22.400 46.175  1.000 21.692 0 104  PHE A CB  1 ? 
ATOM   619  C  CG  . PHE A  1 81  ? -19.657 -23.445 45.611  1.000 23.570 0 104  PHE A CG  1 ? 
ATOM   620  C  CD1 . PHE A  1 81  ? -20.746 -23.904 46.350  1.000 26.059 0 104  PHE A CD1 1 ? 
ATOM   621  C  CD2 . PHE A  1 81  ? -19.426 -24.000 44.358  1.000 21.584 0 104  PHE A CD2 1 ? 
ATOM   622  C  CE1 . PHE A  1 81  ? -21.598 -24.872 45.832  1.000 25.505 0 104  PHE A CE1 1 ? 
ATOM   623  C  CE2 . PHE A  1 81  ? -20.295 -24.944 43.827  1.000 23.805 0 104  PHE A CE2 1 ? 
ATOM   624  C  CZ  . PHE A  1 81  ? -21.378 -25.386 44.569  1.000 26.593 0 104  PHE A CZ  1 ? 
ATOM   625  N  N   . ILE A  1 82  ? -15.726 -21.445 46.543  1.000 19.996 0 105  ILE A N   1 ? 
ATOM   626  C  CA  . ILE A  1 82  ? -14.887 -20.255 46.676  1.000 18.948 0 105  ILE A CA  1 ? 
ATOM   627  C  C   . ILE A  1 82  ? -15.153 -19.383 45.454  1.000 17.715 0 105  ILE A C   1 ? 
ATOM   628  O  O   . ILE A  1 82  ? -15.358 -19.906 44.342  1.000 17.520 0 105  ILE A O   1 ? 
ATOM   629  C  CB  . ILE A  1 82  ? -13.387 -20.593 46.835  1.000 18.236 0 105  ILE A CB  1 ? 
ATOM   630  C  CG1 . ILE A  1 82  ? -12.528 -19.337 47.000  1.000 20.182 0 105  ILE A CG1 1 ? 
ATOM   631  C  CG2 . ILE A  1 82  ? -12.898 -21.489 45.695  1.000 20.291 0 105  ILE A CG2 1 ? 
ATOM   632  C  CD1 . ILE A  1 82  ? -11.062 -19.624 47.309  1.000 21.443 0 105  ILE A CD1 1 ? 
ATOM   633  N  N   . ARG A  1 83  ? -15.259 -18.073 45.718  1.000 17.434 0 106  ARG A N   1 ? 
ATOM   634  C  CA  . ARG A  1 83  ? -15.497 -17.116 44.643  1.000 19.657 0 106  ARG A CA  1 ? 
ATOM   635  C  C   . ARG A  1 83  ? -14.415 -16.055 44.680  1.000 17.611 0 106  ARG A C   1 ? 
ATOM   636  O  O   . ARG A  1 83  ? -14.213 -15.455 45.754  1.000 17.493 0 106  ARG A O   1 ? 
ATOM   637  C  CB  . ARG A  1 83  ? -16.879 -16.457 44.807  1.000 19.255 0 106  ARG A CB  1 ? 
ATOM   638  C  CG  . ARG A  1 83  ? -17.285 -15.606 43.617  1.000 19.332 0 106  ARG A CG  1 ? 
ATOM   639  C  CD  . ARG A  1 83  ? -18.572 -14.828 43.805  1.000 20.626 0 106  ARG A CD  1 ? 
ATOM   640  N  NE  . ARG A  1 83  ? -18.292 -13.475 44.266  1.000 20.808 0 106  ARG A NE  1 ? 
ATOM   641  C  CZ  . ARG A  1 83  ? -19.222 -12.562 44.476  1.000 21.370 0 106  ARG A CZ  1 ? 
ATOM   642  N  NH1 . ARG A  1 83  ? -20.478 -12.863 44.199  1.000 20.480 0 106  ARG A NH1 1 ? 
ATOM   643  N  NH2 . ARG A  1 83  ? -18.877 -11.375 44.953  1.000 19.257 0 106  ARG A NH2 1 ? 
ATOM   644  N  N   . VAL A  1 84  ? -13.788 -15.802 43.512  1.000 18.386 0 107  VAL A N   1 ? 
ATOM   645  C  CA  . VAL A  1 84  ? -12.911 -14.677 43.306  1.000 19.183 0 107  VAL A CA  1 ? 
ATOM   646  C  C   . VAL A  1 84  ? -13.285 -14.006 41.985  1.000 17.110 0 107  VAL A C   1 ? 
ATOM   647  O  O   . VAL A  1 84  ? -13.849 -14.588 41.073  1.000 19.063 0 107  VAL A O   1 ? 
ATOM   648  C  CB  . VAL A  1 84  ? -11.421 -15.052 43.308  1.000 20.435 0 107  VAL A CB  1 ? 
ATOM   649  C  CG1 . VAL A  1 84  ? -11.014 -15.744 44.592  1.000 23.006 0 107  VAL A CG1 1 ? 
ATOM   650  C  CG2 . VAL A  1 84  ? -11.095 -15.890 42.096  1.000 21.744 0 107  VAL A CG2 1 ? 
ATOM   651  N  N   . GLN A  1 85  ? -12.966 -12.733 41.907  1.000 17.942 0 108  GLN A N   1 ? 
ATOM   652  C  CA  . GLN A  1 85  ? -13.266 -11.941 40.736  1.000 16.100 0 108  GLN A CA  1 ? 
ATOM   653  C  C   . GLN A  1 85  ? -12.147 -12.058 39.699  1.000 17.514 0 108  GLN A C   1 ? 
ATOM   654  O  O   . GLN A  1 85  ? -11.033 -12.473 40.037  1.000 17.890 0 108  GLN A O   1 ? 
ATOM   655  C  CB  . GLN A  1 85  ? -13.431 -10.496 41.155  1.000 19.621 0 108  GLN A CB  1 ? 
ATOM   656  C  CG  . GLN A  1 85  ? -14.664 -10.239 41.996  1.000 17.353 0 108  GLN A CG  1 ? 
ATOM   657  C  CD  . GLN A  1 85  ? -15.966 -10.382 41.256  1.000 18.241 0 108  GLN A CD  1 ? 
ATOM   658  O  OE1 . GLN A  1 85  ? -16.051 -10.473 40.025  1.000 18.796 0 108  GLN A OE1 1 ? 
ATOM   659  N  NE2 . GLN A  1 85  ? -17.026 -10.415 42.039  1.000 19.818 0 108  GLN A NE2 1 ? 
ATOM   660  N  N   . PRO A  1 86  ? -12.356 -11.609 38.428  1.000 18.346 0 109  PRO A N   1 ? 
ATOM   661  C  CA  . PRO A  1 86  ? -11.257 -11.415 37.497  1.000 17.411 0 109  PRO A CA  1 ? 
ATOM   662  C  C   . PRO A  1 86  ? -10.225 -10.408 37.966  1.000 19.638 0 109  PRO A C   1 ? 
ATOM   663  O  O   . PRO A  1 86  ? -9.056  -10.525 37.630  1.000 19.666 0 109  PRO A O   1 ? 
ATOM   664  C  CB  . PRO A  1 86  ? -11.910 -10.915 36.214  1.000 20.808 0 109  PRO A CB  1 ? 
ATOM   665  C  CG  . PRO A  1 86  ? -13.276 -10.472 36.626  1.000 18.176 0 109  PRO A CG  1 ? 
ATOM   666  C  CD  . PRO A  1 86  ? -13.657 -11.331 37.808  1.000 17.839 0 109  PRO A CD  1 ? 
ATOM   667  N  N   . ILE A  1 87  ? -10.655 -9.431  38.767  1.000 18.975 0 110  ILE A N   1 ? 
ATOM   668  C  CA  . ILE A  1 87  ? -9.742  -8.394  39.202  1.000 19.833 0 110  ILE A CA  1 ? 
ATOM   669  C  C   . ILE A  1 87  ? -10.485 -7.702  40.334  1.000 18.575 0 110  ILE A C   1 ? 
ATOM   670  O  O   . ILE A  1 87  ? -11.697 -7.545  40.252  1.000 18.299 0 110  ILE A O   1 ? 
ATOM   671  C  CB  . ILE A  1 87  ? -9.363  -7.428  38.053  1.000 19.564 0 110  ILE A CB  1 ? 
ATOM   672  C  CG1 . ILE A  1 87  ? -8.414  -6.324  38.534  1.000 21.735 0 110  ILE A CG1 1 ? 
ATOM   673  C  CG2 . ILE A  1 87  ? -10.620 -6.847  37.427  1.000 20.873 0 110  ILE A CG2 1 ? 
ATOM   674  C  CD1 . ILE A  1 87  ? -7.785  -5.479  37.434  1.000 24.319 0 110  ILE A CD1 1 ? 
ATOM   675  N  N   . GLY A  1 88  ? -9.774  -7.389  41.399  1.000 19.456 0 111  GLY A N   1 ? 
ATOM   676  C  CA  . GLY A  1 88  ? -10.362 -6.697  42.533  1.000 21.366 0 111  GLY A CA  1 ? 
ATOM   677  C  C   . GLY A  1 88  ? -11.297 -7.586  43.354  1.000 20.698 0 111  GLY A C   1 ? 
ATOM   678  O  O   . GLY A  1 88  ? -11.354 -8.823  43.210  1.000 19.930 0 111  GLY A O   1 ? 
ATOM   679  N  N   . GLY A  1 89  ? -11.994 -6.916  44.280  1.000 21.696 0 112  GLY A N   1 ? 
ATOM   680  C  CA  . GLY A  1 89  ? -12.937 -7.577  45.164  1.000 20.430 0 112  GLY A CA  1 ? 
ATOM   681  C  C   . GLY A  1 89  ? -12.268 -8.512  46.163  1.000 18.358 0 112  GLY A C   1 ? 
ATOM   682  O  O   . GLY A  1 89  ? -11.074 -8.420  46.484  1.000 20.345 0 112  GLY A O   1 ? 
ATOM   683  N  N   . PHE A  1 90  ? -13.072 -9.451  46.597  1.000 19.134 0 113  PHE A N   1 ? 
ATOM   684  C  CA  . PHE A  1 90  ? -12.850 -10.173 47.835  1.000 20.053 0 113  PHE A CA  1 ? 
ATOM   685  C  C   . PHE A  1 90  ? -12.868 -11.668 47.581  1.000 19.046 0 113  PHE A C   1 ? 
ATOM   686  O  O   . PHE A  1 90  ? -13.182 -12.119 46.484  1.000 20.647 0 113  PHE A O   1 ? 
ATOM   687  C  CB  . PHE A  1 90  ? -13.910 -9.741  48.866  1.000 21.373 0 113  PHE A CB  1 ? 
ATOM   688  C  CG  . PHE A  1 90  ? -13.936 -8.252  49.074  1.000 21.154 0 113  PHE A CG  1 ? 
ATOM   689  C  CD1 . PHE A  1 90  ? -12.812 -7.592  49.542  1.000 22.607 0 113  PHE A CD1 1 ? 
ATOM   690  C  CD2 . PHE A  1 90  ? -15.041 -7.500  48.699  1.000 21.642 0 113  PHE A CD2 1 ? 
ATOM   691  C  CE1 . PHE A  1 90  ? -12.793 -6.210  49.659  1.000 23.442 0 113  PHE A CE1 1 ? 
ATOM   692  C  CE2 . PHE A  1 90  ? -15.025 -6.118  48.813  1.000 22.187 0 113  PHE A CE2 1 ? 
ATOM   693  C  CZ  . PHE A  1 90  ? -13.888 -5.472  49.271  1.000 22.104 0 113  PHE A CZ  1 ? 
ATOM   694  N  N   . VAL A  1 91  ? -12.607 -12.432 48.645  1.000 20.043 0 114  VAL A N   1 ? 
ATOM   695  C  CA  . VAL A  1 91  ? -12.620 -13.888 48.607  1.000 21.281 0 114  VAL A CA  1 ? 
ATOM   696  C  C   . VAL A  1 91  ? -13.825 -14.316 49.427  1.000 22.256 0 114  VAL A C   1 ? 
ATOM   697  O  O   . VAL A  1 91  ? -13.862 -14.014 50.614  1.000 21.690 0 114  VAL A O   1 ? 
ATOM   698  C  CB  . VAL A  1 91  ? -11.337 -14.535 49.171  1.000 21.502 0 114  VAL A CB  1 ? 
ATOM   699  C  CG1 . VAL A  1 91  ? -11.407 -16.058 49.124  1.000 22.012 0 114  VAL A CG1 1 ? 
ATOM   700  C  CG2 . VAL A  1 91  ? -10.064 -14.069 48.490  1.000 22.033 0 114  VAL A CG2 1 ? 
ATOM   701  N  N   . PHE A  1 92  ? -14.822 -14.927 48.777  1.000 20.608 0 115  PHE A N   1 ? 
ATOM   702  C  CA  . PHE A  1 92  ? -16.007 -15.400 49.468  1.000 21.626 0 115  PHE A CA  1 ? 
ATOM   703  C  C   . PHE A  1 92  ? -16.038 -16.919 49.496  1.000 22.069 0 115  PHE A C   1 ? 
ATOM   704  O  O   . PHE A  1 92  ? -15.818 -17.568 48.479  1.000 21.519 0 115  PHE A O   1 ? 
ATOM   705  C  CB  . PHE A  1 92  ? -17.266 -14.865 48.786  1.000 20.728 0 115  PHE A CB  1 ? 
ATOM   706  C  CG  . PHE A  1 92  ? -17.558 -13.396 49.025  1.000 21.742 0 115  PHE A CG  1 ? 
ATOM   707  C  CD1 . PHE A  1 92  ? -18.255 -12.986 50.145  1.000 22.506 0 115  PHE A CD1 1 ? 
ATOM   708  C  CD2 . PHE A  1 92  ? -17.176 -12.418 48.118  1.000 20.196 0 115  PHE A CD2 1 ? 
ATOM   709  C  CE1 . PHE A  1 92  ? -18.551 -11.647 50.365  1.000 20.778 0 115  PHE A CE1 1 ? 
ATOM   710  C  CE2 . PHE A  1 92  ? -17.446 -11.077 48.356  1.000 18.819 0 115  PHE A CE2 1 ? 
ATOM   711  C  CZ  . PHE A  1 92  ? -18.141 -10.697 49.472  1.000 21.090 0 115  PHE A CZ  1 ? 
ATOM   712  N  N   . LEU A  1 93  ? -16.428 -17.464 50.655  1.000 23.496 0 116  LEU A N   1 ? 
ATOM   713  C  CA  . LEU A  1 93  ? -16.585 -18.897 50.855  1.000 22.896 0 116  LEU A CA  1 ? 
ATOM   714  C  C   . LEU A  1 93  ? -18.034 -19.176 51.264  1.000 24.183 0 116  LEU A C   1 ? 
ATOM   715  O  O   . LEU A  1 93  ? -18.599 -18.420 52.064  1.000 24.064 0 116  LEU A O   1 ? 
ATOM   716  C  CB  . LEU A  1 93  ? -15.634 -19.330 51.978  1.000 23.295 0 116  LEU A CB  1 ? 
ATOM   717  C  CG  . LEU A  1 93  ? -14.154 -18.943 51.839  1.000 27.186 0 116  LEU A CG  1 ? 
ATOM   718  C  CD1 . LEU A  1 93  ? -13.340 -19.467 53.009  1.000 29.136 0 116  LEU A CD1 1 ? 
ATOM   719  C  CD2 . LEU A  1 93  ? -13.564 -19.473 50.544  1.000 28.090 0 116  LEU A CD2 1 ? 
ATOM   720  N  N   . SER A  1 94  ? -18.628 -20.248 50.707  1.000 22.003 0 117  SER A N   1 ? 
ATOM   721  C  CA  . SER A  1 94  ? -20.026 -20.543 50.970  1.000 23.404 0 117  SER A CA  1 ? 
ATOM   722  C  C   . SER A  1 94  ? -20.166 -21.441 52.198  1.000 26.131 0 117  SER A C   1 ? 
ATOM   723  O  O   . SER A  1 94  ? -19.250 -22.153 52.563  1.000 25.627 0 117  SER A O   1 ? 
ATOM   724  C  CB  . SER A  1 94  ? -20.730 -21.148 49.777  1.000 21.610 0 117  SER A CB  1 ? 
ATOM   725  O  OG  . SER A  1 94  ? -20.328 -22.491 49.511  1.000 21.835 0 117  SER A OG  1 ? 
ATOM   726  N  N   A ARG A  1 95  ? -21.349 -21.381 52.810  0.500 26.877 0 118  ARG A N   1 ? 
ATOM   727  N  N   B ARG A  1 95  ? -21.348 -21.385 52.808  0.500 24.649 0 118  ARG A N   1 ? 
ATOM   728  C  CA  A ARG A  1 95  ? -21.744 -22.264 53.890  0.500 31.838 0 118  ARG A CA  1 ? 
ATOM   729  C  CA  B ARG A  1 95  ? -21.741 -22.279 53.878  0.500 27.599 0 118  ARG A CA  1 ? 
ATOM   730  C  C   A ARG A  1 95  ? -23.188 -22.643 53.587  0.500 29.236 0 118  ARG A C   1 ? 
ATOM   731  C  C   B ARG A  1 95  ? -23.188 -22.645 53.585  0.500 27.085 0 118  ARG A C   1 ? 
ATOM   732  O  O   A ARG A  1 95  ? -24.074 -21.795 53.690  0.500 30.477 0 118  ARG A O   1 ? 
ATOM   733  O  O   B ARG A  1 95  ? -24.071 -21.794 53.694  0.500 28.593 0 118  ARG A O   1 ? 
ATOM   734  C  CB  A ARG A  1 95  ? -21.612 -21.552 55.246  0.500 39.224 0 118  ARG A CB  1 ? 
ATOM   735  C  CB  B ARG A  1 95  ? -21.599 -21.589 55.242  0.500 30.442 0 118  ARG A CB  1 ? 
ATOM   736  C  CG  A ARG A  1 95  ? -21.476 -22.486 56.446  0.500 45.666 0 118  ARG A CG  1 ? 
ATOM   737  C  CG  B ARG A  1 95  ? -21.817 -22.505 56.443  0.500 31.830 0 118  ARG A CG  1 ? 
ATOM   738  C  CD  A ARG A  1 95  ? -21.832 -21.858 57.790  0.500 51.027 0 118  ARG A CD  1 ? 
ATOM   739  C  CD  B ARG A  1 95  ? -21.621 -21.777 57.765  0.500 33.153 0 118  ARG A CD  1 ? 
ATOM   740  N  NE  A ARG A  1 95  ? -20.990 -20.752 58.232  0.500 55.099 0 118  ARG A NE  1 ? 
ATOM   741  N  NE  B ARG A  1 95  ? -20.218 -21.505 58.060  0.500 31.011 0 118  ARG A NE  1 ? 
ATOM   742  C  CZ  A ARG A  1 95  ? -19.712 -20.854 58.593  0.500 53.717 0 118  ARG A CZ  1 ? 
ATOM   743  C  CZ  B ARG A  1 95  ? -19.803 -20.549 58.883  0.500 30.743 0 118  ARG A CZ  1 ? 
ATOM   744  N  NH1 A ARG A  1 95  ? -19.082 -22.011 58.510  0.500 57.060 0 118  ARG A NH1 1 ? 
ATOM   745  N  NH1 B ARG A  1 95  ? -20.681 -19.768 59.496  0.500 30.372 0 118  ARG A NH1 1 ? 
ATOM   746  N  NH2 A ARG A  1 95  ? -19.068 -19.788 59.037  0.500 51.336 0 118  ARG A NH2 1 ? 
ATOM   747  N  NH2 B ARG A  1 95  ? -18.511 -20.372 59.077  0.500 32.243 0 118  ARG A NH2 1 ? 
ATOM   748  N  N   . GLY A  1 96  ? -23.392 -23.872 53.114  1.000 26.896 0 119  GLY A N   1 ? 
ATOM   749  C  CA  . GLY A  1 96  ? -24.698 -24.313 52.636  1.000 29.001 0 119  GLY A CA  1 ? 
ATOM   750  C  C   . GLY A  1 96  ? -24.884 -24.141 51.133  1.000 29.231 0 119  GLY A C   1 ? 
ATOM   751  O  O   . GLY A  1 96  ? -26.008 -24.073 50.666  1.000 29.609 0 119  GLY A O   1 ? 
ATOM   752  N  N   . GLY A  1 97  ? -23.784 -24.046 50.360  1.000 27.680 0 120  GLY A N   1 ? 
ATOM   753  C  CA  . GLY A  1 97  ? -23.902 -23.974 48.913  1.000 26.032 0 120  GLY A CA  1 ? 
ATOM   754  C  C   . GLY A  1 97  ? -24.158 -22.562 48.392  1.000 26.490 0 120  GLY A C   1 ? 
ATOM   755  O  O   . GLY A  1 97  ? -24.097 -21.566 49.116  1.000 28.411 0 120  GLY A O   1 ? 
ATOM   756  N  N   . LEU A  1 98  ? -24.443 -22.495 47.092  1.000 26.437 0 121  LEU A N   1 ? 
ATOM   757  C  CA  . LEU A  1 98  ? -24.474 -21.246 46.347  1.000 25.495 0 121  LEU A CA  1 ? 
ATOM   758  C  C   . LEU A  1 98  ? -25.588 -20.333 46.838  1.000 29.085 0 121  LEU A C   1 ? 
ATOM   759  O  O   . LEU A  1 98  ? -25.462 -19.097 46.814  1.000 26.989 0 121  LEU A O   1 ? 
ATOM   760  C  CB  . LEU A  1 98  ? -24.685 -21.577 44.870  1.000 25.089 0 121  LEU A CB  1 ? 
ATOM   761  C  CG  . LEU A  1 98  ? -23.497 -22.239 44.179  1.000 24.753 0 121  LEU A CG  1 ? 
ATOM   762  C  CD1 . LEU A  1 98  ? -23.870 -22.622 42.759  1.000 27.062 0 121  LEU A CD1 1 ? 
ATOM   763  C  CD2 . LEU A  1 98  ? -22.276 -21.324 44.200  1.000 24.988 0 121  LEU A CD2 1 ? 
ATOM   764  N  N   . ASP A  1 99  ? -26.679 -20.975 47.285  1.000 29.344 0 122  ASP A N   1 ? 
ATOM   765  C  CA  . ASP A  1 99  ? -27.823 -20.257 47.798  1.000 29.019 0 122  ASP A CA  1 ? 
ATOM   766  C  C   . ASP A  1 99  ? -27.837 -20.260 49.333  1.000 31.304 0 122  ASP A C   1 ? 
ATOM   767  O  O   . ASP A  1 99  ? -28.860 -19.956 49.923  1.000 31.927 0 122  ASP A O   1 ? 
ATOM   768  C  CB  . ASP A  1 99  ? -29.087 -20.885 47.217  1.000 29.092 0 122  ASP A CB  1 ? 
ATOM   769  C  CG  . ASP A  1 99  ? -29.113 -20.918 45.698  1.000 31.108 0 122  ASP A CG  1 ? 
ATOM   770  O  OD1 . ASP A  1 99  ? -28.607 -19.986 45.054  1.000 30.075 0 122  ASP A OD1 1 ? 
ATOM   771  O  OD2 . ASP A  1 99  ? -29.697 -21.849 45.175  1.000 33.973 0 122  ASP A OD2 1 ? 
ATOM   772  N  N   . GLY A  1 100 ? -26.703 -20.555 49.955  1.000 26.754 0 123  GLY A N   1 ? 
ATOM   773  C  CA  . GLY A  1 100 ? -26.556 -20.553 51.399  1.000 30.223 0 123  GLY A CA  1 ? 
ATOM   774  C  C   . GLY A  1 100 ? -26.032 -19.215 51.904  1.000 27.914 0 123  GLY A C   1 ? 
ATOM   775  O  O   . GLY A  1 100 ? -26.318 -18.162 51.323  1.000 26.135 0 123  GLY A O   1 ? 
ATOM   776  N  N   . LYS A  1 101 ? -25.222 -19.300 52.964  1.000 26.244 0 124  LYS A N   1 ? 
ATOM   777  C  CA  . LYS A  1 101 ? -24.635 -18.143 53.613  1.000 26.448 0 124  LYS A CA  1 ? 
ATOM   778  C  C   . LYS A  1 101 ? -23.249 -17.989 53.003  1.000 28.587 0 124  LYS A C   1 ? 
ATOM   779  O  O   . LYS A  1 101 ? -22.565 -18.982 52.773  1.000 27.268 0 124  LYS A O   1 ? 
ATOM   780  C  CB  . LYS A  1 101 ? -24.547 -18.411 55.119  1.000 32.939 0 124  LYS A CB  1 ? 
ATOM   781  C  CG  . LYS A  1 101 ? -23.898 -17.342 55.983  1.000 36.171 0 124  LYS A CG  1 ? 
ATOM   782  C  CD  . LYS A  1 101 ? -23.889 -17.693 57.460  1.000 39.621 0 124  LYS A CD  1 ? 
ATOM   783  C  CE  . LYS A  1 101 ? -25.301 -17.802 58.004  1.000 50.422 0 124  LYS A CE  1 ? 
ATOM   784  N  NZ  . LYS A  1 101 ? -25.360 -17.661 59.481  1.000 61.110 0 124  LYS A NZ  1 ? 
ATOM   785  N  N   . TRP A  1 102 ? -22.877 -16.759 52.644  1.000 24.811 0 125  TRP A N   1 ? 
ATOM   786  C  CA  . TRP A  1 102 ? -21.529 -16.498 52.187  1.000 23.594 0 125  TRP A CA  1 ? 
ATOM   787  C  C   . TRP A  1 102 ? -20.779 -15.692 53.230  1.000 23.903 0 125  TRP A C   1 ? 
ATOM   788  O  O   . TRP A  1 102 ? -21.340 -14.785 53.848  1.000 24.566 0 125  TRP A O   1 ? 
ATOM   789  C  CB  . TRP A  1 102 ? -21.579 -15.768 50.839  1.000 23.082 0 125  TRP A CB  1 ? 
ATOM   790  C  CG  . TRP A  1 102 ? -22.055 -16.637 49.710  1.000 21.186 0 125  TRP A CG  1 ? 
ATOM   791  C  CD1 . TRP A  1 102 ? -23.342 -16.863 49.323  1.000 21.735 0 125  TRP A CD1 1 ? 
ATOM   792  C  CD2 . TRP A  1 102 ? -21.216 -17.324 48.755  1.000 21.477 0 125  TRP A CD2 1 ? 
ATOM   793  N  NE1 . TRP A  1 102 ? -23.360 -17.708 48.234  1.000 22.261 0 125  TRP A NE1 1 ? 
ATOM   794  C  CE2 . TRP A  1 102 ? -22.071 -17.973 47.845  1.000 20.877 0 125  TRP A CE2 1 ? 
ATOM   795  C  CE3 . TRP A  1 102 ? -19.833 -17.453 48.592  1.000 23.606 0 125  TRP A CE3 1 ? 
ATOM   796  C  CZ2 . TRP A  1 102 ? -21.581 -18.737 46.789  1.000 21.373 0 125  TRP A CZ2 1 ? 
ATOM   797  C  CZ3 . TRP A  1 102 ? -19.353 -18.210 47.551  1.000 23.956 0 125  TRP A CZ3 1 ? 
ATOM   798  C  CH2 . TRP A  1 102 ? -20.216 -18.819 46.643  1.000 22.429 0 125  TRP A CH2 1 ? 
ATOM   799  N  N   . LEU A  1 103 ? -19.497 -16.003 53.390  1.000 25.926 0 126  LEU A N   1 ? 
ATOM   800  C  CA  . LEU A  1 103 ? -18.634 -15.247 54.287  1.000 24.784 0 126  LEU A CA  1 ? 
ATOM   801  C  C   . LEU A  1 103 ? -17.450 -14.722 53.513  1.000 24.673 0 126  LEU A C   1 ? 
ATOM   802  O  O   . LEU A  1 103 ? -16.918 -15.412 52.660  1.000 22.404 0 126  LEU A O   1 ? 
ATOM   803  C  CB  . LEU A  1 103 ? -18.190 -16.172 55.428  1.000 28.448 0 126  LEU A CB  1 ? 
ATOM   804  C  CG  . LEU A  1 103 ? -19.358 -16.714 56.252  1.000 31.847 0 126  LEU A CG  1 ? 
ATOM   805  C  CD1 . LEU A  1 103 ? -19.662 -18.151 55.846  1.000 31.699 0 126  LEU A CD1 1 ? 
ATOM   806  C  CD2 . LEU A  1 103 ? -19.088 -16.577 57.726  1.000 34.711 0 126  LEU A CD2 1 ? 
ATOM   807  N  N   . ALA A  1 104 ? -16.984 -13.535 53.879  1.000 23.526 0 127  ALA A N   1 ? 
ATOM   808  C  CA  . ALA A  1 104 ? -15.801 -12.998 53.236  1.000 21.897 0 127  ALA A CA  1 ? 
ATOM   809  C  C   . ALA A  1 104 ? -14.576 -13.220 54.121  1.000 22.817 0 127  ALA A C   1 ? 
ATOM   810  O  O   . ALA A  1 104 ? -14.682 -13.121 55.336  1.000 24.233 0 127  ALA A O   1 ? 
ATOM   811  C  CB  . ALA A  1 104 ? -16.059 -11.546 52.952  1.000 20.880 0 127  ALA A CB  1 ? 
ATOM   812  N  N   . VAL A  1 105 ? -13.426 -13.533 53.501  1.000 19.726 0 128  VAL A N   1 ? 
ATOM   813  C  CA  . VAL A  1 105 ? -12.162 -13.763 54.194  1.000 21.142 0 128  VAL A CA  1 ? 
ATOM   814  C  C   . VAL A  1 105 ? -11.518 -12.439 54.602  1.000 23.660 0 128  VAL A C   1 ? 
ATOM   815  O  O   . VAL A  1 105 ? -11.332 -11.534 53.781  1.000 20.931 0 128  VAL A O   1 ? 
ATOM   816  C  CB  . VAL A  1 105 ? -11.229 -14.591 53.305  1.000 21.869 0 128  VAL A CB  1 ? 
ATOM   817  C  CG1 . VAL A  1 105 ? -9.867  -14.781 53.940  1.000 25.157 0 128  VAL A CG1 1 ? 
ATOM   818  C  CG2 . VAL A  1 105 ? -11.844 -15.937 52.985  1.000 25.052 0 128  VAL A CG2 1 ? 
ATOM   819  N  N   . THR A  1 106 ? -11.136 -12.335 55.887  1.000 23.500 0 129  THR A N   1 ? 
ATOM   820  C  CA  . THR A  1 106 ? -10.496 -11.124 56.379  1.000 23.273 0 129  THR A CA  1 ? 
ATOM   821  C  C   . THR A  1 106 ? -8.977  -11.176 56.204  1.000 23.435 0 129  THR A C   1 ? 
ATOM   822  O  O   . THR A  1 106 ? -8.383  -12.239 55.945  1.000 24.928 0 129  THR A O   1 ? 
ATOM   823  C  CB  . THR A  1 106 ? -10.799 -10.860 57.866  1.000 22.114 0 129  THR A CB  1 ? 
ATOM   824  O  OG1 . THR A  1 106 ? -10.069 -11.844 58.610  1.000 22.750 0 129  THR A OG1 1 ? 
ATOM   825  C  CG2 . THR A  1 106 ? -12.274 -10.902 58.174  1.000 24.413 0 129  THR A CG2 1 ? 
ATOM   826  N  N   . ASN A  1 107 ? -8.333  -10.016 56.398  1.000 24.719 0 130  ASN A N   1 ? 
ATOM   827  C  CA  . ASN A  1 107 ? -6.882  -9.963  56.298  1.000 27.790 0 130  ASN A CA  1 ? 
ATOM   828  C  C   . ASN A  1 107 ? -6.207  -10.820 57.357  1.000 30.490 0 130  ASN A C   1 ? 
ATOM   829  O  O   . ASN A  1 107 ? -5.087  -11.245 57.132  1.000 29.357 0 130  ASN A O   1 ? 
ATOM   830  C  CB  . ASN A  1 107 ? -6.286  -8.571  56.395  1.000 27.615 0 130  ASN A CB  1 ? 
ATOM   831  C  CG  . ASN A  1 107 ? -6.431  -7.818  55.103  1.000 29.558 0 130  ASN A CG  1 ? 
ATOM   832  O  OD1 . ASN A  1 107 ? -6.183  -8.379  54.040  1.000 29.756 0 130  ASN A OD1 1 ? 
ATOM   833  N  ND2 . ASN A  1 107 ? -6.852  -6.569  55.193  1.000 29.832 0 130  ASN A ND2 1 ? 
ATOM   834  N  N   . ASP A  1 108 ? -6.880  -11.113 58.474  1.000 28.530 0 131  ASP A N   1 ? 
ATOM   835  C  CA  . ASP A  1 108 ? -6.254  -11.924 59.504  1.000 30.981 0 131  ASP A CA  1 ? 
ATOM   836  C  C   . ASP A  1 108 ? -6.779  -13.346 59.503  1.000 31.711 0 131  ASP A C   1 ? 
ATOM   837  O  O   . ASP A  1 108 ? -6.597  -14.062 60.480  1.000 30.793 0 131  ASP A O   1 ? 
ATOM   838  C  CB  . ASP A  1 108 ? -6.331  -11.279 60.890  1.000 36.078 0 131  ASP A CB  1 ? 
ATOM   839  C  CG  . ASP A  1 108 ? -7.714  -10.914 61.388  1.000 46.063 0 131  ASP A CG  1 ? 
ATOM   840  O  OD1 . ASP A  1 108 ? -8.653  -10.822 60.575  1.000 52.496 0 131  ASP A OD1 1 ? 
ATOM   841  O  OD2 . ASP A  1 108 ? -7.829  -10.677 62.599  1.000 55.855 0 131  ASP A OD2 1 ? 
ATOM   842  N  N   . GLY A  1 109 ? -7.394  -13.784 58.404  1.000 27.569 0 132  GLY A N   1 ? 
ATOM   843  C  CA  . GLY A  1 109 ? -7.683  -15.199 58.245  1.000 28.089 0 132  GLY A CA  1 ? 
ATOM   844  C  C   . GLY A  1 109 ? -8.937  -15.644 59.002  1.000 32.231 0 132  GLY A C   1 ? 
ATOM   845  O  O   . GLY A  1 109 ? -9.079  -16.814 59.313  1.000 33.106 0 132  GLY A O   1 ? 
ATOM   846  N  N   . LYS A  1 110 ? -9.866  -14.712 59.230  1.000 27.275 0 133  LYS A N   1 ? 
ATOM   847  C  CA  . LYS A  1 110 ? -11.162 -14.990 59.806  1.000 26.758 0 133  LYS A CA  1 ? 
ATOM   848  C  C   . LYS A  1 110 ? -12.246 -14.797 58.750  1.000 26.356 0 133  LYS A C   1 ? 
ATOM   849  O  O   . LYS A  1 110 ? -11.959 -14.399 57.601  1.000 30.099 0 133  LYS A O   1 ? 
ATOM   850  C  CB  . LYS A  1 110 ? -11.379 -14.063 61.018  1.000 29.374 0 133  LYS A CB  1 ? 
ATOM   851  C  CG  . LYS A  1 110 ? -10.397 -14.312 62.159  1.000 34.557 0 133  LYS A CG  1 ? 
ATOM   852  C  CD  . LYS A  1 110 ? -10.519 -13.317 63.275  1.000 42.957 0 133  LYS A CD  1 ? 
ATOM   853  C  CE  . LYS A  1 110 ? -9.681  -13.677 64.485  1.000 51.437 0 133  LYS A CE  1 ? 
ATOM   854  N  NZ  . LYS A  1 110 ? -9.758  -12.597 65.506  1.000 56.572 0 133  LYS A NZ  1 ? 
ATOM   855  N  N   . LEU A  1 111 ? -13.492 -15.073 59.155  1.000 24.484 0 134  LEU A N   1 ? 
ATOM   856  C  CA  . LEU A  1 111 ? -14.623 -15.014 58.251  1.000 25.592 0 134  LEU A CA  1 ? 
ATOM   857  C  C   . LEU A  1 111 ? -15.578 -13.908 58.669  1.000 25.653 0 134  LEU A C   1 ? 
ATOM   858  O  O   . LEU A  1 111 ? -15.995 -13.885 59.814  1.000 27.950 0 134  LEU A O   1 ? 
ATOM   859  C  CB  . LEU A  1 111 ? -15.327 -16.365 58.261  1.000 26.377 0 134  LEU A CB  1 ? 
ATOM   860  C  CG  . LEU A  1 111 ? -14.506 -17.480 57.632  1.000 29.816 0 134  LEU A CG  1 ? 
ATOM   861  C  CD1 . LEU A  1 111 ? -15.214 -18.816 57.676  1.000 31.148 0 134  LEU A CD1 1 ? 
ATOM   862  C  CD2 . LEU A  1 111 ? -14.183 -17.112 56.195  1.000 30.157 0 134  LEU A CD2 1 ? 
ATOM   863  N  N   . GLU A  1 112 ? -15.919 -13.013 57.736  1.000 23.851 0 135  GLU A N   1 ? 
ATOM   864  C  CA  . GLU A  1 112 ? -16.844 -11.908 57.988  1.000 24.080 0 135  GLU A CA  1 ? 
ATOM   865  C  C   . GLU A  1 112 ? -18.222 -12.233 57.414  1.000 24.113 0 135  GLU A C   1 ? 
ATOM   866  O  O   . GLU A  1 112 ? -18.395 -12.352 56.196  1.000 24.018 0 135  GLU A O   1 ? 
ATOM   867  C  CB  . GLU A  1 112 ? -16.260 -10.648 57.357  1.000 24.248 0 135  GLU A CB  1 ? 
ATOM   868  C  CG  . GLU A  1 112 ? -17.134 -9.412  57.413  1.000 27.874 0 135  GLU A CG  1 ? 
ATOM   869  C  CD  . GLU A  1 112 ? -17.389 -8.958  58.842  1.000 26.543 0 135  GLU A CD  1 ? 
ATOM   870  O  OE1 . GLU A  1 112 ? -16.454 -8.375  59.446  1.000 26.177 0 135  GLU A OE1 1 ? 
ATOM   871  O  OE2 . GLU A  1 112 ? -18.483 -9.222  59.332  1.000 25.900 0 135  GLU A OE2 1 ? 
ATOM   872  N  N   . GLU A  1 113 ? -19.229 -12.351 58.289  1.000 22.154 0 136  GLU A N   1 ? 
ATOM   873  C  CA  . GLU A  1 113 ? -20.598 -12.583 57.861  1.000 26.077 0 136  GLU A CA  1 ? 
ATOM   874  C  C   . GLU A  1 113 ? -21.239 -11.313 57.329  1.000 25.866 0 136  GLU A C   1 ? 
ATOM   875  O  O   . GLU A  1 113 ? -22.124 -11.387 56.474  1.000 26.895 0 136  GLU A O   1 ? 
ATOM   876  C  CB  . GLU A  1 113 ? -21.491 -13.104 58.990  1.000 36.440 0 136  GLU A CB  1 ? 
ATOM   877  C  CG  . GLU A  1 113 ? -21.099 -14.487 59.484  1.000 47.035 0 136  GLU A CG  1 ? 
ATOM   878  C  CD  . GLU A  1 113 ? -22.048 -15.148 60.484  1.000 58.856 0 136  GLU A CD  1 ? 
ATOM   879  O  OE1 . GLU A  1 113 ? -23.171 -14.633 60.654  1.000 57.024 0 136  GLU A OE1 1 ? 
ATOM   880  O  OE2 . GLU A  1 113 ? -21.654 -16.181 61.091  1.000 66.307 0 136  GLU A OE2 1 ? 
ATOM   881  N  N   . ASP A  1 114 ? -20.845 -10.151 57.879  1.000 24.724 0 137  ASP A N   1 ? 
ATOM   882  C  CA  . ASP A  1 114 ? -21.555 -8.912  57.634  1.000 23.752 0 137  ASP A CA  1 ? 
ATOM   883  C  C   . ASP A  1 114 ? -20.814 -8.127  56.558  1.000 24.463 0 137  ASP A C   1 ? 
ATOM   884  O  O   . ASP A  1 114 ? -20.439 -6.988  56.775  1.000 23.333 0 137  ASP A O   1 ? 
ATOM   885  C  CB  . ASP A  1 114 ? -21.709 -8.119  58.944  1.000 25.831 0 137  ASP A CB  1 ? 
ATOM   886  C  CG  . ASP A  1 114 ? -22.580 -6.883  58.868  1.000 25.811 0 137  ASP A CG  1 ? 
ATOM   887  O  OD1 . ASP A  1 114 ? -23.368 -6.799  57.921  1.000 22.870 0 137  ASP A OD1 1 ? 
ATOM   888  O  OD2 . ASP A  1 114 ? -22.408 -5.979  59.744  1.000 25.883 0 137  ASP A OD2 1 ? 
ATOM   889  N  N   . TRP A  1 115 ? -20.603 -8.744  55.386  1.000 24.635 0 138  TRP A N   1 ? 
ATOM   890  C  CA  . TRP A  1 115 ? -19.810 -8.142  54.321  1.000 23.684 0 138  TRP A CA  1 ? 
ATOM   891  C  C   . TRP A  1 115 ? -20.591 -7.024  53.626  1.000 22.346 0 138  TRP A C   1 ? 
ATOM   892  O  O   . TRP A  1 115 ? -20.042 -6.256  52.840  1.000 22.783 0 138  TRP A O   1 ? 
ATOM   893  C  CB  . TRP A  1 115 ? -19.352 -9.244  53.339  1.000 25.555 0 138  TRP A CB  1 ? 
ATOM   894  C  CG  . TRP A  1 115 ? -20.425 -10.250 53.008  1.000 21.964 0 138  TRP A CG  1 ? 
ATOM   895  C  CD1 . TRP A  1 115 ? -20.515 -11.529 53.480  1.000 24.827 0 138  TRP A CD1 1 ? 
ATOM   896  C  CD2 . TRP A  1 115 ? -21.587 -10.057 52.179  1.000 20.850 0 138  TRP A CD2 1 ? 
ATOM   897  N  NE1 . TRP A  1 115 ? -21.612 -12.155 52.964  1.000 25.117 0 138  TRP A NE1 1 ? 
ATOM   898  C  CE2 . TRP A  1 115 ? -22.303 -11.269 52.186  1.000 24.394 0 138  TRP A CE2 1 ? 
ATOM   899  C  CE3 . TRP A  1 115 ? -22.077 -8.992  51.419  1.000 22.333 0 138  TRP A CE3 1 ? 
ATOM   900  C  CZ2 . TRP A  1 115 ? -23.476 -11.437 51.477  1.000 25.250 0 138  TRP A CZ2 1 ? 
ATOM   901  C  CZ3 . TRP A  1 115 ? -23.261 -9.151  50.735  1.000 24.097 0 138  TRP A CZ3 1 ? 
ATOM   902  C  CH2 . TRP A  1 115 ? -23.963 -10.354 50.787  1.000 26.673 0 138  TRP A CH2 1 ? 
ATOM   903  N  N   . LYS A  1 116 ? -21.900 -6.885  53.898  1.000 20.693 0 139  LYS A N   1 ? 
ATOM   904  C  CA  . LYS A  1 116 ? -22.641 -5.808  53.258  1.000 21.542 0 139  LYS A CA  1 ? 
ATOM   905  C  C   . LYS A  1 116 ? -22.254 -4.451  53.850  1.000 21.348 0 139  LYS A C   1 ? 
ATOM   906  O  O   . LYS A  1 116 ? -22.492 -3.408  53.246  1.000 22.383 0 139  LYS A O   1 ? 
ATOM   907  C  CB  . LYS A  1 116 ? -24.143 -6.088  53.355  1.000 27.042 0 139  LYS A CB  1 ? 
ATOM   908  C  CG  . LYS A  1 116 ? -24.761 -5.739  54.692  1.000 33.191 0 139  LYS A CG  1 ? 
ATOM   909  C  CD  . LYS A  1 116 ? -26.265 -5.624  54.650  1.000 40.798 0 139  LYS A CD  1 ? 
ATOM   910  C  CE  . LYS A  1 116 ? -26.968 -6.936  54.867  1.000 47.360 0 139  LYS A CE  1 ? 
ATOM   911  N  NZ  . LYS A  1 116 ? -28.336 -6.688  55.376  1.000 58.207 0 139  LYS A NZ  1 ? 
ATOM   912  N  N   . ASP A  1 117 ? -21.573 -4.469  54.998  1.000 22.204 0 140  ASP A N   1 ? 
ATOM   913  C  CA  . ASP A  1 117 ? -21.144 -3.262  55.692  1.000 23.037 0 140  ASP A CA  1 ? 
ATOM   914  C  C   . ASP A  1 117 ? -19.844 -2.746  55.085  1.000 22.865 0 140  ASP A C   1 ? 
ATOM   915  O  O   . ASP A  1 117 ? -18.811 -3.410  55.193  1.000 23.224 0 140  ASP A O   1 ? 
ATOM   916  C  CB  . ASP A  1 117 ? -20.965 -3.586  57.178  1.000 22.756 0 140  ASP A CB  1 ? 
ATOM   917  C  CG  . ASP A  1 117 ? -20.526 -2.435  58.064  1.000 25.170 0 140  ASP A CG  1 ? 
ATOM   918  O  OD1 . ASP A  1 117 ? -19.740 -1.647  57.609  1.000 23.026 0 140  ASP A OD1 1 ? 
ATOM   919  O  OD2 . ASP A  1 117 ? -20.879 -2.450  59.259  1.000 24.601 0 140  ASP A OD2 1 ? 
ATOM   920  N  N   . PRO A  1 118 ? -19.833 -1.560  54.434  1.000 21.629 0 141  PRO A N   1 ? 
ATOM   921  C  CA  . PRO A  1 118 ? -18.657 -1.123  53.677  1.000 24.389 0 141  PRO A CA  1 ? 
ATOM   922  C  C   . PRO A  1 118 ? -17.443 -0.849  54.552  1.000 27.133 0 141  PRO A C   1 ? 
ATOM   923  O  O   . PRO A  1 118 ? -16.308 -0.980  54.074  1.000 26.539 0 141  PRO A O   1 ? 
ATOM   924  C  CB  . PRO A  1 118 ? -19.136 0.134   52.927  1.000 26.972 0 141  PRO A CB  1 ? 
ATOM   925  C  CG  . PRO A  1 118 ? -20.332 0.608   53.697  1.000 24.912 0 141  PRO A CG  1 ? 
ATOM   926  C  CD  . PRO A  1 118 ? -20.972 -0.661  54.211  1.000 24.043 0 141  PRO A CD  1 ? 
ATOM   927  N  N   . GLU A  1 119 ? -17.686 -0.473  55.813  1.000 25.572 0 142  GLU A N   1 ? 
ATOM   928  C  CA  . GLU A  1 119 ? -16.601 -0.266  56.745  1.000 26.011 0 142  GLU A CA  1 ? 
ATOM   929  C  C   . GLU A  1 119 ? -15.914 -1.602  57.039  1.000 25.267 0 142  GLU A C   1 ? 
ATOM   930  O  O   . GLU A  1 119 ? -14.683 -1.641  57.033  1.000 22.598 0 142  GLU A O   1 ? 
ATOM   931  C  CB  . GLU A  1 119 ? -17.050 0.449   58.034  1.000 27.055 0 142  GLU A CB  1 ? 
ATOM   932  C  CG  . GLU A  1 119 ? -15.875 0.873   58.918  1.000 27.505 0 142  GLU A CG  1 ? 
ATOM   933  C  CD  . GLU A  1 119 ? -15.005 2.017   58.384  1.000 28.734 0 142  GLU A CD  1 ? 
ATOM   934  O  OE1 . GLU A  1 119 ? -15.364 2.616   57.365  1.000 28.414 0 142  GLU A OE1 1 ? 
ATOM   935  O  OE2 . GLU A  1 119 ? -13.929 2.303   58.988  1.000 35.288 0 142  GLU A OE2 1 ? 
ATOM   936  N  N   . LYS A  1 120 ? -16.687 -2.668  57.294  1.000 25.116 0 143  LYS A N   1 ? 
ATOM   937  C  CA  . LYS A  1 120 ? -16.119 -3.982  57.571  1.000 27.145 0 143  LYS A CA  1 ? 
ATOM   938  C  C   . LYS A  1 120 ? -15.397 -4.582  56.354  1.000 27.230 0 143  LYS A C   1 ? 
ATOM   939  O  O   . LYS A  1 120 ? -14.465 -5.403  56.518  1.000 25.347 0 143  LYS A O   1 ? 
ATOM   940  C  CB  . LYS A  1 120 ? -17.222 -4.947  58.016  1.000 29.072 0 143  LYS A CB  1 ? 
ATOM   941  C  CG  . LYS A  1 120 ? -17.760 -4.625  59.414  1.000 27.758 0 143  LYS A CG  1 ? 
ATOM   942  C  CD  . LYS A  1 120 ? -18.820 -5.555  59.866  1.000 26.664 0 143  LYS A CD  1 ? 
ATOM   943  C  CE  . LYS A  1 120 ? -19.261 -5.200  61.280  1.000 27.232 0 143  LYS A CE  1 ? 
ATOM   944  N  NZ  . LYS A  1 120 ? -20.401 -6.039  61.688  1.000 26.660 0 143  LYS A NZ  1 ? 
ATOM   945  N  N   . ARG A  1 121 ? -15.793 -4.127  55.153  1.000 21.416 0 144  ARG A N   1 ? 
ATOM   946  C  CA  . ARG A  1 121 ? -15.165 -4.597  53.914  1.000 22.200 0 144  ARG A CA  1 ? 
ATOM   947  C  C   . ARG A  1 121 ? -13.731 -4.091  53.794  1.000 25.067 0 144  ARG A C   1 ? 
ATOM   948  O  O   . ARG A  1 121 ? -12.904 -4.642  53.043  1.000 21.131 0 144  ARG A O   1 ? 
ATOM   949  C  CB  . ARG A  1 121 ? -16.012 -4.223  52.692  1.000 24.145 0 144  ARG A CB  1 ? 
ATOM   950  C  CG  . ARG A  1 121 ? -17.254 -5.089  52.537  1.000 21.499 0 144  ARG A CG  1 ? 
ATOM   951  C  CD  . ARG A  1 121 ? -17.672 -5.170  51.082  1.000 22.307 0 144  ARG A CD  1 ? 
ATOM   952  N  NE  . ARG A  1 121 ? -18.021 -3.905  50.487  1.000 22.620 0 144  ARG A NE  1 ? 
ATOM   953  C  CZ  . ARG A  1 121 ? -19.177 -3.276  50.661  1.000 22.824 0 144  ARG A CZ  1 ? 
ATOM   954  N  NH1 . ARG A  1 121 ? -20.123 -3.783  51.443  1.000 22.094 0 144  ARG A NH1 1 ? 
ATOM   955  N  NH2 . ARG A  1 121 ? -19.381 -2.133  50.041  1.000 24.962 0 144  ARG A NH2 1 ? 
ATOM   956  N  N   . LYS A  1 122 ? -13.408 -3.031  54.556  1.000 21.865 0 145  LYS A N   1 ? 
ATOM   957  C  CA  . LYS A  1 122 ? -12.047 -2.506  54.520  1.000 22.886 0 145  LYS A CA  1 ? 
ATOM   958  C  C   . LYS A  1 122 ? -11.010 -3.461  55.126  1.000 23.377 0 145  LYS A C   1 ? 
ATOM   959  O  O   . LYS A  1 122 ? -9.824  -3.285  54.840  1.000 26.615 0 145  LYS A O   1 ? 
ATOM   960  C  CB  . LYS A  1 122 ? -12.022 -1.169  55.259  1.000 24.751 0 145  LYS A CB  1 ? 
ATOM   961  C  CG  . LYS A  1 122 ? -12.797 -0.075  54.548  1.000 25.545 0 145  LYS A CG  1 ? 
ATOM   962  C  CD  . LYS A  1 122 ? -12.789 1.238   55.320  1.000 26.093 0 145  LYS A CD  1 ? 
ATOM   963  C  CE  . LYS A  1 122 ? -13.497 2.331   54.542  1.000 31.736 0 145  LYS A CE  1 ? 
ATOM   964  N  NZ  . LYS A  1 122 ? -13.588 3.594   55.324  1.000 38.039 0 145  LYS A NZ  1 ? 
ATOM   965  N  N   A ASN A  1 123 ? -11.361 -4.422  55.990  0.500 21.753 0 146  ASN A N   1 ? 
ATOM   966  N  N   B ASN A  1 123 ? -11.508 -4.445  55.898  0.500 21.412 0 146  ASN A N   1 ? 
ATOM   967  C  CA  A ASN A  1 123 ? -10.323 -5.342  56.464  0.500 23.185 0 146  ASN A CA  1 ? 
ATOM   968  C  CA  B ASN A  1 123 ? -10.733 -5.412  56.672  0.500 22.927 0 146  ASN A CA  1 ? 
ATOM   969  C  C   A ASN A  1 123 ? -10.527 -6.732  55.858  0.500 21.860 0 146  ASN A C   1 ? 
ATOM   970  C  C   B ASN A  1 123 ? -10.424 -6.649  55.810  0.500 21.839 0 146  ASN A C   1 ? 
ATOM   971  O  O   A ASN A  1 123 ? -10.204 -7.754  56.480  0.500 23.429 0 146  ASN A O   1 ? 
ATOM   972  O  O   B ASN A  1 123 ? -9.575  -7.457  56.180  0.500 23.783 0 146  ASN A O   1 ? 
ATOM   973  C  CB  A ASN A  1 123 ? -10.197 -5.433  57.997  0.500 22.472 0 146  ASN A CB  1 ? 
ATOM   974  C  CB  B ASN A  1 123 ? -11.488 -5.688  57.991  0.500 22.867 0 146  ASN A CB  1 ? 
ATOM   975  C  CG  A ASN A  1 123 ? -8.873  -6.053  58.427  0.500 21.849 0 146  ASN A CG  1 ? 
ATOM   976  C  CG  B ASN A  1 123 ? -10.892 -6.679  58.977  0.500 22.150 0 146  ASN A CG  1 ? 
ATOM   977  O  OD1 A ASN A  1 123 ? -8.867  -7.044  59.160  0.500 31.900 0 146  ASN A OD1 1 ? 
ATOM   978  O  OD1 B ASN A  1 123 ? -9.711  -6.605  59.300  0.500 23.050 0 146  ASN A OD1 1 ? 
ATOM   979  N  ND2 A ASN A  1 123 ? -7.756  -5.522  57.951  0.500 17.770 0 146  ASN A ND2 1 ? 
ATOM   980  N  ND2 B ASN A  1 123 ? -11.715 -7.544  59.568  0.500 19.815 0 146  ASN A ND2 1 ? 
ATOM   981  N  N   . LEU A  1 124 ? -11.070 -6.772  54.640  1.000 21.426 0 147  LEU A N   1 ? 
ATOM   982  C  CA  . LEU A  1 124 ? -11.130 -8.038  53.903  1.000 19.415 0 147  LEU A CA  1 ? 
ATOM   983  C  C   . LEU A  1 124 ? -9.876  -8.255  53.070  1.000 19.365 0 147  LEU A C   1 ? 
ATOM   984  O  O   . LEU A  1 124 ? -9.324  -7.331  52.497  1.000 19.692 0 147  LEU A O   1 ? 
ATOM   985  C  CB  . LEU A  1 124 ? -12.380 -8.073  53.026  1.000 19.267 0 147  LEU A CB  1 ? 
ATOM   986  C  CG  . LEU A  1 124 ? -13.714 -8.034  53.759  1.000 19.597 0 147  LEU A CG  1 ? 
ATOM   987  C  CD1 . LEU A  1 124 ? -14.849 -8.000  52.770  1.000 21.398 0 147  LEU A CD1 1 ? 
ATOM   988  C  CD2 . LEU A  1 124 ? -13.855 -9.212  54.721  1.000 21.889 0 147  LEU A CD2 1 ? 
ATOM   989  N  N   . LYS A  1 125 ? -9.491  -9.520  52.946  1.000 20.652 0 148  LYS A N   1 ? 
ATOM   990  C  CA  . LYS A  1 125 ? -8.450  -9.955  52.027  1.000 22.229 0 148  LYS A CA  1 ? 
ATOM   991  C  C   . LYS A  1 125 ? -8.768  -9.537  50.586  1.000 20.996 0 148  LYS A C   1 ? 
ATOM   992  O  O   . LYS A  1 125 ? -9.831  -9.842  50.045  1.000 21.928 0 148  LYS A O   1 ? 
ATOM   993  C  CB  . LYS A  1 125 ? -8.316  -11.480 52.097  1.000 23.416 0 148  LYS A CB  1 ? 
ATOM   994  C  CG  . LYS A  1 125 ? -7.110  -12.022 51.314  1.000 25.844 0 148  LYS A CG  1 ? 
ATOM   995  C  CD  . LYS A  1 125 ? -5.792  -11.553 51.883  1.000 28.138 0 148  LYS A CD  1 ? 
ATOM   996  C  CE  . LYS A  1 125 ? -4.615  -12.208 51.193  1.000 31.324 0 148  LYS A CE  1 ? 
ATOM   997  N  NZ  . LYS A  1 125 ? -3.349  -11.651 51.693  1.000 31.474 0 148  LYS A NZ  1 ? 
ATOM   998  N  N   . LYS A  1 126 ? -7.802  -8.877  49.944  1.000 19.798 0 149  LYS A N   1 ? 
ATOM   999  C  CA  . LYS A  1 126 ? -7.880  -8.511  48.543  1.000 21.912 0 149  LYS A CA  1 ? 
ATOM   1000 C  C   . LYS A  1 126 ? -6.717  -9.169  47.814  1.000 21.812 0 149  LYS A C   1 ? 
ATOM   1001 O  O   . LYS A  1 126 ? -5.556  -8.785  47.996  1.000 22.667 0 149  LYS A O   1 ? 
ATOM   1002 C  CB  . LYS A  1 126 ? -7.807  -6.987  48.449  1.000 24.890 0 149  LYS A CB  1 ? 
ATOM   1003 C  CG  . LYS A  1 126 ? -9.037  -6.286  49.027  1.000 30.717 0 149  LYS A CG  1 ? 
ATOM   1004 C  CD  . LYS A  1 126 ? -8.966  -4.792  48.936  1.000 35.425 0 149  LYS A CD  1 ? 
ATOM   1005 C  CE  . LYS A  1 126 ? -9.145  -4.254  47.530  1.000 50.186 0 149  LYS A CE  1 ? 
ATOM   1006 N  NZ  . LYS A  1 126 ? -10.554 -4.288  47.061  1.000 59.179 0 149  LYS A NZ  1 ? 
ATOM   1007 N  N   . LEU A  1 127 ? -7.020  -10.199 47.030  1.000 20.007 0 150  LEU A N   1 ? 
ATOM   1008 C  CA  . LEU A  1 127 ? -5.975  -10.816 46.233  1.000 19.131 0 150  LEU A CA  1 ? 
ATOM   1009 C  C   . LEU A  1 127 ? -5.689  -9.910  45.033  1.000 19.746 0 150  LEU A C   1 ? 
ATOM   1010 O  O   . LEU A  1 127 ? -6.620  -9.472  44.325  1.000 21.905 0 150  LEU A O   1 ? 
ATOM   1011 C  CB  . LEU A  1 127 ? -6.430  -12.197 45.763  1.000 18.099 0 150  LEU A CB  1 ? 
ATOM   1012 C  CG  . LEU A  1 127 ? -6.706  -13.236 46.847  1.000 20.604 0 150  LEU A CG  1 ? 
ATOM   1013 C  CD1 . LEU A  1 127 ? -7.138  -14.546 46.234  1.000 22.108 0 150  LEU A CD1 1 ? 
ATOM   1014 C  CD2 . LEU A  1 127 ? -5.508  -13.460 47.722  1.000 21.942 0 150  LEU A CD2 1 ? 
ATOM   1015 N  N   . GLY A  1 128 ? -4.400  -9.745  44.730  1.000 18.977 0 151  GLY A N   1 ? 
ATOM   1016 C  CA  . GLY A  1 128 ? -3.947  -8.804  43.720  1.000 19.400 0 151  GLY A CA  1 ? 
ATOM   1017 C  C   . GLY A  1 128 ? -3.859  -9.421  42.329  1.000 18.840 0 151  GLY A C   1 ? 
ATOM   1018 O  O   . GLY A  1 128 ? -4.052  -10.631 42.169  1.000 20.846 0 151  GLY A O   1 ? 
ATOM   1019 N  N   . GLY A  1 129 ? -3.692  -8.556  41.327  1.000 19.437 0 152  GLY A N   1 ? 
ATOM   1020 C  CA  . GLY A  1 129 ? -3.489  -8.980  39.956  1.000 20.310 0 152  GLY A CA  1 ? 
ATOM   1021 C  C   . GLY A  1 129 ? -4.786  -9.319  39.226  1.000 19.261 0 152  GLY A C   1 ? 
ATOM   1022 O  O   . GLY A  1 129 ? -5.889  -9.247  39.747  1.000 20.718 0 152  GLY A O   1 ? 
ATOM   1023 N  N   . ILE A  1 130 ? -4.637  -9.703  37.968  1.000 19.258 0 153  ILE A N   1 ? 
ATOM   1024 C  CA  . ILE A  1 130 ? -5.737  -10.277 37.228  1.000 18.150 0 153  ILE A CA  1 ? 
ATOM   1025 C  C   . ILE A  1 130 ? -5.700  -11.777 37.489  1.000 17.992 0 153  ILE A C   1 ? 
ATOM   1026 O  O   . ILE A  1 130 ? -4.675  -12.417 37.248  1.000 15.782 0 153  ILE A O   1 ? 
ATOM   1027 C  CB  . ILE A  1 130 ? -5.594  -9.911  35.746  1.000 19.574 0 153  ILE A CB  1 ? 
ATOM   1028 C  CG1 . ILE A  1 130 ? -5.727  -8.394  35.551  1.000 21.447 0 153  ILE A CG1 1 ? 
ATOM   1029 C  CG2 . ILE A  1 130 ? -6.582  -10.681 34.881  1.000 19.641 0 153  ILE A CG2 1 ? 
ATOM   1030 C  CD1 . ILE A  1 130 ? -5.168  -7.922  34.252  1.000 22.922 0 153  ILE A CD1 1 ? 
ATOM   1031 N  N   . MET A  1 131 ? -6.835  -12.296 37.967  1.000 16.144 0 154  MET A N   1 ? 
ATOM   1032 C  CA  . MET A  1 131 ? -6.951  -13.663 38.401  1.000 17.064 0 154  MET A CA  1 ? 
ATOM   1033 C  C   . MET A  1 131 ? -7.729  -14.475 37.371  1.000 17.567 0 154  MET A C   1 ? 
ATOM   1034 O  O   . MET A  1 131 ? -8.668  -13.960 36.743  1.000 18.350 0 154  MET A O   1 ? 
ATOM   1035 C  CB  . MET A  1 131 ? -7.662  -13.682 39.751  1.000 19.837 0 154  MET A CB  1 ? 
ATOM   1036 C  CG  . MET A  1 131 ? -6.763  -13.207 40.873  1.000 21.441 0 154  MET A CG  1 ? 
ATOM   1037 S  SD  . MET A  1 131 ? -7.594  -13.225 42.466  1.000 23.872 0 154  MET A SD  1 ? 
ATOM   1038 C  CE  . MET A  1 131 ? -8.659  -11.789 42.358  1.000 24.934 0 154  MET A CE  1 ? 
ATOM   1039 N  N   . ARG A  1 132 ? -7.361  -15.762 37.254  1.000 18.038 0 155  ARG A N   1 ? 
ATOM   1040 C  CA  . ARG A  1 132 ? -8.181  -16.754 36.576  1.000 16.956 0 155  ARG A CA  1 ? 
ATOM   1041 C  C   . ARG A  1 132 ? -8.803  -17.696 37.605  1.000 19.456 0 155  ARG A C   1 ? 
ATOM   1042 O  O   . ARG A  1 132 ? -9.311  -17.234 38.621  1.000 19.649 0 155  ARG A O   1 ? 
ATOM   1043 C  CB  . ARG A  1 132 ? -7.415  -17.385 35.416  1.000 18.362 0 155  ARG A CB  1 ? 
ATOM   1044 C  CG  . ARG A  1 132 ? -7.381  -16.483 34.185  1.000 18.759 0 155  ARG A CG  1 ? 
ATOM   1045 C  CD  . ARG A  1 132 ? -7.074  -17.252 32.936  1.000 20.547 0 155  ARG A CD  1 ? 
ATOM   1046 N  NE  . ARG A  1 132 ? -8.128  -18.172 32.564  1.000 19.951 0 155  ARG A NE  1 ? 
ATOM   1047 C  CZ  . ARG A  1 132 ? -7.984  -19.054 31.577  1.000 21.716 0 155  ARG A CZ  1 ? 
ATOM   1048 N  NH1 . ARG A  1 132 ? -6.905  -19.018 30.814  1.000 21.210 0 155  ARG A NH1 1 ? 
ATOM   1049 N  NH2 . ARG A  1 132 ? -8.927  -19.946 31.332  1.000 22.466 0 155  ARG A NH2 1 ? 
ATOM   1050 N  N   . THR A  1 133 ? -8.783  -19.004 37.345  1.000 17.307 0 156  THR A N   1 ? 
ATOM   1051 C  CA  . THR A  1 133 ? -9.672  -19.932 38.032  1.000 18.286 0 156  THR A CA  1 ? 
ATOM   1052 C  C   . THR A  1 133 ? -8.990  -20.602 39.218  1.000 19.734 0 156  THR A C   1 ? 
ATOM   1053 O  O   . THR A  1 133 ? -7.936  -21.203 39.041  1.000 19.669 0 156  THR A O   1 ? 
ATOM   1054 C  CB  . THR A  1 133 ? -10.182 -21.022 37.079  1.000 20.811 0 156  THR A CB  1 ? 
ATOM   1055 O  OG1 . THR A  1 133 ? -10.670 -20.385 35.896  1.000 20.081 0 156  THR A OG1 1 ? 
ATOM   1056 C  CG2 . THR A  1 133 ? -11.296 -21.845 37.710  1.000 21.055 0 156  THR A CG2 1 ? 
ATOM   1057 N  N   . PRO A  1 134 ? -9.545  -20.494 40.444  1.000 19.690 0 157  PRO A N   1 ? 
ATOM   1058 C  CA  . PRO A  1 134 ? -9.087  -21.294 41.574  1.000 19.598 0 157  PRO A CA  1 ? 
ATOM   1059 C  C   . PRO A  1 134 ? -9.095  -22.758 41.163  1.000 18.902 0 157  PRO A C   1 ? 
ATOM   1060 O  O   . PRO A  1 134 ? -10.045 -23.188 40.521  1.000 19.002 0 157  PRO A O   1 ? 
ATOM   1061 C  CB  . PRO A  1 134 ? -10.098 -21.033 42.677  1.000 20.871 0 157  PRO A CB  1 ? 
ATOM   1062 C  CG  . PRO A  1 134 ? -10.616 -19.624 42.356  1.000 20.129 0 157  PRO A CG  1 ? 
ATOM   1063 C  CD  . PRO A  1 134 ? -10.659 -19.610 40.831  1.000 21.270 0 157  PRO A CD  1 ? 
ATOM   1064 N  N   . VAL A  1 135 ? -8.043  -23.498 41.554  1.000 17.697 0 158  VAL A N   1 ? 
ATOM   1065 C  CA  . VAL A  1 135 ? -8.001  -24.929 41.281  1.000 20.091 0 158  VAL A CA  1 ? 
ATOM   1066 C  C   . VAL A  1 135 ? -7.534  -25.637 42.555  1.000 20.764 0 158  VAL A C   1 ? 
ATOM   1067 O  O   . VAL A  1 135 ? -6.493  -25.281 43.098  1.000 19.616 0 158  VAL A O   1 ? 
ATOM   1068 C  CB  . VAL A  1 135 ? -7.139  -25.267 40.056  1.000 22.577 0 158  VAL A CB  1 ? 
ATOM   1069 C  CG1 . VAL A  1 135 ? -5.698  -24.833 40.218  1.000 22.819 0 158  VAL A CG1 1 ? 
ATOM   1070 C  CG2 . VAL A  1 135 ? -7.209  -26.762 39.665  1.000 25.444 0 158  VAL A CG2 1 ? 
ATOM   1071 N  N   . PHE A  1 136 ? -8.303  -26.664 42.976  1.000 20.374 0 159  PHE A N   1 ? 
ATOM   1072 C  CA  . PHE A  1 136 ? -7.947  -27.469 44.145  1.000 20.065 0 159  PHE A CA  1 ? 
ATOM   1073 C  C   . PHE A  1 136 ? -7.018  -28.590 43.685  1.000 21.263 0 159  PHE A C   1 ? 
ATOM   1074 O  O   . PHE A  1 136 ? -7.328  -29.260 42.704  1.000 20.167 0 159  PHE A O   1 ? 
ATOM   1075 C  CB  . PHE A  1 136 ? -9.212  -27.985 44.836  1.000 21.157 0 159  PHE A CB  1 ? 
ATOM   1076 C  CG  . PHE A  1 136 ? -9.963  -26.932 45.604  1.000 22.241 0 159  PHE A CG  1 ? 
ATOM   1077 C  CD1 . PHE A  1 136 ? -10.821 -26.066 44.939  1.000 21.314 0 159  PHE A CD1 1 ? 
ATOM   1078 C  CD2 . PHE A  1 136 ? -9.764  -26.746 46.968  1.000 21.808 0 159  PHE A CD2 1 ? 
ATOM   1079 C  CE1 . PHE A  1 136 ? -11.528 -25.102 45.637  1.000 22.439 0 159  PHE A CE1 1 ? 
ATOM   1080 C  CE2 . PHE A  1 136 ? -10.450 -25.748 47.655  1.000 20.261 0 159  PHE A CE2 1 ? 
ATOM   1081 C  CZ  . PHE A  1 136 ? -11.310 -24.909 46.976  1.000 19.764 0 159  PHE A CZ  1 ? 
ATOM   1082 N  N   . VAL A  1 137 ? -5.875  -28.733 44.359  1.000 20.521 0 160  VAL A N   1 ? 
ATOM   1083 C  CA  . VAL A  1 137 ? -4.849  -29.708 44.008  1.000 21.953 0 160  VAL A CA  1 ? 
ATOM   1084 C  C   . VAL A  1 137 ? -4.472  -30.515 45.260  1.000 23.299 0 160  VAL A C   1 ? 
ATOM   1085 O  O   . VAL A  1 137 ? -4.884  -30.156 46.375  1.000 22.822 0 160  VAL A O   1 ? 
ATOM   1086 C  CB  . VAL A  1 137 ? -3.652  -28.984 43.384  1.000 21.779 0 160  VAL A CB  1 ? 
ATOM   1087 C  CG1 . VAL A  1 137 ? -4.100  -28.266 42.114  1.000 23.668 0 160  VAL A CG1 1 ? 
ATOM   1088 C  CG2 . VAL A  1 137 ? -2.959  -28.003 44.323  1.000 21.258 0 160  VAL A CG2 1 ? 
ATOM   1089 N  N   . ASN A  1 138 ? -3.672  -31.576 45.057  1.000 22.505 0 161  ASN A N   1 ? 
ATOM   1090 C  CA  . ASN A  1 138 ? -3.135  -32.390 46.140  1.000 25.628 0 161  ASN A CA  1 ? 
ATOM   1091 C  C   . ASN A  1 138 ? -4.286  -32.955 46.983  1.000 25.189 0 161  ASN A C   1 ? 
ATOM   1092 O  O   . ASN A  1 138 ? -4.416  -32.687 48.196  1.000 25.051 0 161  ASN A O   1 ? 
ATOM   1093 C  CB  . ASN A  1 138 ? -2.137  -31.626 46.998  1.000 27.871 0 161  ASN A CB  1 ? 
ATOM   1094 C  CG  . ASN A  1 138 ? -1.499  -32.539 48.018  1.000 31.956 0 161  ASN A CG  1 ? 
ATOM   1095 O  OD1 . ASN A  1 138 ? -1.473  -33.739 47.794  1.000 32.202 0 161  ASN A OD1 1 ? 
ATOM   1096 N  ND2 . ASN A  1 138 ? -0.984  -31.998 49.107  1.000 33.597 0 161  ASN A ND2 1 ? 
ATOM   1097 N  N   . LYS A  1 139 ? -5.138  -33.700 46.282  1.000 26.720 0 162  LYS A N   1 ? 
ATOM   1098 C  CA  . LYS A  1 139 ? -6.344  -34.324 46.802  1.000 30.922 0 162  LYS A CA  1 ? 
ATOM   1099 C  C   . LYS A  1 139 ? -7.161  -33.317 47.595  1.000 32.718 0 162  LYS A C   1 ? 
ATOM   1100 O  O   . LYS A  1 139 ? -7.641  -33.628 48.694  1.000 26.681 0 162  LYS A O   1 ? 
ATOM   1101 C  CB  . LYS A  1 139 ? -5.948  -35.519 47.682  1.000 31.833 0 162  LYS A CB  1 ? 
ATOM   1102 C  CG  . LYS A  1 139 ? -4.917  -36.413 47.011  1.000 37.356 0 162  LYS A CG  1 ? 
ATOM   1103 C  CD  . LYS A  1 139 ? -4.815  -37.775 47.583  1.000 39.520 0 162  LYS A CD  1 ? 
ATOM   1104 C  CE  . LYS A  1 139 ? -3.991  -38.674 46.694  1.000 43.509 0 162  LYS A CE  1 ? 
ATOM   1105 N  NZ  . LYS A  1 139 ? -4.011  -40.042 47.236  1.000 49.301 0 162  LYS A NZ  1 ? 
ATOM   1106 N  N   . GLY A  1 140 ? -7.302  -32.108 47.017  1.000 28.491 0 163  GLY A N   1 ? 
ATOM   1107 C  CA  . GLY A  1 140 ? -8.234  -31.110 47.515  1.000 27.066 0 163  GLY A CA  1 ? 
ATOM   1108 C  C   . GLY A  1 140 ? -7.703  -30.302 48.688  1.000 25.253 0 163  GLY A C   1 ? 
ATOM   1109 O  O   . GLY A  1 140 ? -8.403  -29.429 49.182  1.000 28.480 0 163  GLY A O   1 ? 
ATOM   1110 N  N   . ARG A  1 141 ? -6.456  -30.524 49.093  1.000 22.958 0 164  ARG A N   1 ? 
ATOM   1111 C  CA  . ARG A  1 141 ? -5.953  -29.938 50.314  1.000 25.626 0 164  ARG A CA  1 ? 
ATOM   1112 C  C   . ARG A  1 141 ? -5.347  -28.560 50.089  1.000 26.489 0 164  ARG A C   1 ? 
ATOM   1113 O  O   . ARG A  1 141 ? -5.095  -27.836 51.051  1.000 25.244 0 164  ARG A O   1 ? 
ATOM   1114 C  CB  . ARG A  1 141 ? -4.971  -30.896 51.001  1.000 28.979 0 164  ARG A CB  1 ? 
ATOM   1115 C  CG  . ARG A  1 141 ? -5.664  -32.138 51.564  1.000 28.751 0 164  ARG A CG  1 ? 
ATOM   1116 C  CD  . ARG A  1 141 ? -4.688  -33.197 52.042  1.000 29.904 0 164  ARG A CD  1 ? 
ATOM   1117 N  NE  . ARG A  1 141 ? -3.932  -33.781 50.942  1.000 34.569 0 164  ARG A NE  1 ? 
ATOM   1118 C  CZ  . ARG A  1 141 ? -3.113  -34.832 51.072  1.000 39.889 0 164  ARG A CZ  1 ? 
ATOM   1119 N  NH1 . ARG A  1 141 ? -3.013  -35.439 52.236  1.000 37.562 0 164  ARG A NH1 1 ? 
ATOM   1120 N  NH2 . ARG A  1 141 ? -2.386  -35.261 50.056  1.000 34.763 0 164  ARG A NH2 1 ? 
ATOM   1121 N  N   . ARG A  1 142 ? -5.180  -28.153 48.823  1.000 24.861 0 165  ARG A N   1 ? 
ATOM   1122 C  CA  . ARG A  1 142 ? -4.607  -26.841 48.544  1.000 22.077 0 165  ARG A CA  1 ? 
ATOM   1123 C  C   . ARG A  1 142 ? -5.424  -26.195 47.430  1.000 22.698 0 165  ARG A C   1 ? 
ATOM   1124 O  O   . ARG A  1 142 ? -5.836  -26.881 46.490  1.000 20.412 0 165  ARG A O   1 ? 
ATOM   1125 C  CB  . ARG A  1 142 ? -3.132  -26.974 48.154  1.000 22.456 0 165  ARG A CB  1 ? 
ATOM   1126 C  CG  . ARG A  1 142 ? -2.536  -25.713 47.550  1.000 22.483 0 165  ARG A CG  1 ? 
ATOM   1127 C  CD  . ARG A  1 142 ? -1.075  -25.797 47.228  1.000 23.488 0 165  ARG A CD  1 ? 
ATOM   1128 N  NE  . ARG A  1 142 ? -0.311  -25.632 48.449  1.000 26.032 0 165  ARG A NE  1 ? 
ATOM   1129 C  CZ  . ARG A  1 142 ? 0.981   -25.360 48.504  1.000 25.205 0 165  ARG A CZ  1 ? 
ATOM   1130 N  NH1 . ARG A  1 142 ? 1.706   -25.391 47.402  1.000 23.889 0 165  ARG A NH1 1 ? 
ATOM   1131 N  NH2 . ARG A  1 142 ? 1.554   -25.080 49.667  1.000 25.191 0 165  ARG A NH2 1 ? 
ATOM   1132 N  N   . VAL A  1 143 ? -5.669  -24.887 47.527  1.000 21.279 0 166  VAL A N   1 ? 
ATOM   1133 C  CA  . VAL A  1 143 ? -6.262  -24.192 46.380  1.000 20.172 0 166  VAL A CA  1 ? 
ATOM   1134 C  C   . VAL A  1 143 ? -5.277  -23.139 45.900  1.000 19.244 0 166  VAL A C   1 ? 
ATOM   1135 O  O   . VAL A  1 143 ? -4.624  -22.477 46.696  1.000 20.873 0 166  VAL A O   1 ? 
ATOM   1136 C  CB  . VAL A  1 143 ? -7.658  -23.621 46.676  1.000 21.690 0 166  VAL A CB  1 ? 
ATOM   1137 C  CG1 . VAL A  1 143 ? -7.638  -22.628 47.827  1.000 22.183 0 166  VAL A CG1 1 ? 
ATOM   1138 C  CG2 . VAL A  1 143 ? -8.287  -22.992 45.427  1.000 21.272 0 166  VAL A CG2 1 ? 
ATOM   1139 N  N   . ILE A  1 144 ? -5.047  -23.100 44.572  1.000 19.914 0 167  ILE A N   1 ? 
ATOM   1140 C  CA  . ILE A  1 144 ? -4.221  -22.062 44.000  1.000 20.244 0 167  ILE A CA  1 ? 
ATOM   1141 C  C   . ILE A  1 144 ? -5.016  -21.246 42.983  1.000 19.021 0 167  ILE A C   1 ? 
ATOM   1142 O  O   . ILE A  1 144 ? -5.856  -21.771 42.269  1.000 18.651 0 167  ILE A O   1 ? 
ATOM   1143 C  CB  . ILE A  1 144 ? -2.909  -22.606 43.418  1.000 24.695 0 167  ILE A CB  1 ? 
ATOM   1144 C  CG1 . ILE A  1 144 ? -3.075  -23.252 42.045  1.000 26.640 0 167  ILE A CG1 1 ? 
ATOM   1145 C  CG2 . ILE A  1 144 ? -2.250  -23.551 44.401  1.000 27.135 0 167  ILE A CG2 1 ? 
ATOM   1146 C  CD1 . ILE A  1 144 ? -1.741  -23.623 41.471  1.000 27.461 0 167  ILE A CD1 1 ? 
ATOM   1147 N  N   . VAL A  1 145 ? -4.681  -19.956 42.901  1.000 17.216 0 168  VAL A N   1 ? 
ATOM   1148 C  CA  . VAL A  1 145 ? -5.332  -19.065 41.947  1.000 18.079 0 168  VAL A CA  1 ? 
ATOM   1149 C  C   . VAL A  1 145 ? -4.273  -18.419 41.077  1.000 17.795 0 168  VAL A C   1 ? 
ATOM   1150 O  O   . VAL A  1 145 ? -3.505  -17.620 41.586  1.000 19.363 0 168  VAL A O   1 ? 
ATOM   1151 C  CB  . VAL A  1 145 ? -6.154  -17.969 42.656  1.000 17.654 0 168  VAL A CB  1 ? 
ATOM   1152 C  CG1 . VAL A  1 145 ? -6.943  -17.157 41.630  1.000 18.610 0 168  VAL A CG1 1 ? 
ATOM   1153 C  CG2 . VAL A  1 145 ? -7.081  -18.542 43.699  1.000 18.653 0 168  VAL A CG2 1 ? 
ATOM   1154 N  N   . PRO A  1 146 ? -4.236  -18.652 39.751  1.000 17.807 0 169  PRO A N   1 ? 
ATOM   1155 C  CA  . PRO A  1 146 ? -3.277  -17.960 38.891  1.000 19.126 0 169  PRO A CA  1 ? 
ATOM   1156 C  C   . PRO A  1 146 ? -3.592  -16.463 38.869  1.000 17.519 0 169  PRO A C   1 ? 
ATOM   1157 O  O   . PRO A  1 146 ? -4.770  -16.111 38.793  1.000 18.266 0 169  PRO A O   1 ? 
ATOM   1158 C  CB  . PRO A  1 146 ? -3.500  -18.586 37.509  1.000 21.104 0 169  PRO A CB  1 ? 
ATOM   1159 C  CG  . PRO A  1 146 ? -4.300  -19.847 37.778  1.000 19.991 0 169  PRO A CG  1 ? 
ATOM   1160 C  CD  . PRO A  1 146 ? -5.128  -19.534 38.995  1.000 21.172 0 169  PRO A CD  1 ? 
ATOM   1161 N  N   . PHE A  1 147 ? -2.549  -15.631 38.946  1.000 17.966 0 170  PHE A N   1 ? 
ATOM   1162 C  CA  . PHE A  1 147 ? -2.713  -14.196 38.769  1.000 16.958 0 170  PHE A CA  1 ? 
ATOM   1163 C  C   . PHE A  1 147 ? -1.564  -13.631 37.961  1.000 17.747 0 170  PHE A C   1 ? 
ATOM   1164 O  O   . PHE A  1 147 ? -0.435  -14.147 38.014  1.000 18.611 0 170  PHE A O   1 ? 
ATOM   1165 C  CB  . PHE A  1 147 ? -2.887  -13.433 40.091  1.000 17.990 0 170  PHE A CB  1 ? 
ATOM   1166 C  CG  . PHE A  1 147 ? -1.651  -13.239 40.932  1.000 19.418 0 170  PHE A CG  1 ? 
ATOM   1167 C  CD1 . PHE A  1 147 ? -1.204  -14.254 41.756  1.000 18.352 0 170  PHE A CD1 1 ? 
ATOM   1168 C  CD2 . PHE A  1 147 ? -0.927  -12.054 40.890  1.000 21.807 0 170  PHE A CD2 1 ? 
ATOM   1169 C  CE1 . PHE A  1 147 ? -0.073  -14.077 42.538  1.000 20.510 0 170  PHE A CE1 1 ? 
ATOM   1170 C  CE2 . PHE A  1 147 ? 0.247   -11.894 41.633  1.000 23.044 0 170  PHE A CE2 1 ? 
ATOM   1171 C  CZ  . PHE A  1 147 ? 0.633   -12.896 42.498  1.000 21.311 0 170  PHE A CZ  1 ? 
ATOM   1172 N  N   . HIS A  1 148 ? -1.820  -12.526 37.253  1.000 18.475 0 171  HIS A N   1 ? 
ATOM   1173 C  CA  . HIS A  1 148 ? -0.729  -11.934 36.510  1.000 19.132 0 171  HIS A CA  1 ? 
ATOM   1174 C  C   . HIS A  1 148 ? -0.725  -10.418 36.590  1.000 20.119 0 171  HIS A C   1 ? 
ATOM   1175 O  O   . HIS A  1 148 ? -1.726  -9.808  36.920  1.000 21.884 0 171  HIS A O   1 ? 
ATOM   1176 C  CB  . HIS A  1 148 ? -0.720  -12.371 35.044  1.000 19.331 0 171  HIS A CB  1 ? 
ATOM   1177 C  CG  . HIS A  1 148 ? -1.870  -11.855 34.234  1.000 19.352 0 171  HIS A CG  1 ? 
ATOM   1178 N  ND1 . HIS A  1 148 ? -3.086  -12.507 34.085  1.000 19.104 0 171  HIS A ND1 1 ? 
ATOM   1179 C  CD2 . HIS A  1 148 ? -1.962  -10.709 33.563  1.000 18.587 0 171  HIS A CD2 1 ? 
ATOM   1180 C  CE1 . HIS A  1 148 ? -3.853  -11.738 33.324  1.000 20.990 0 171  HIS A CE1 1 ? 
ATOM   1181 N  NE2 . HIS A  1 148 ? -3.190  -10.653 32.981  1.000 19.751 0 171  HIS A NE2 1 ? 
ATOM   1182 N  N   . ASN A  1 149 ? 0.453   -9.920  36.229  1.000 20.555 0 172  ASN A N   1 ? 
ATOM   1183 C  CA  . ASN A  1 149 ? 0.805   -8.559  35.842  1.000 25.366 0 172  ASN A CA  1 ? 
ATOM   1184 C  C   . ASN A  1 149 ? 1.244   -8.642  34.364  1.000 25.025 0 172  ASN A C   1 ? 
ATOM   1185 O  O   . ASN A  1 149 ? 1.993   -9.556  33.929  1.000 23.011 0 172  ASN A O   1 ? 
ATOM   1186 C  CB  . ASN A  1 149 ? 1.900   -8.058  36.807  1.000 26.768 0 172  ASN A CB  1 ? 
ATOM   1187 C  CG  . ASN A  1 149 ? 2.476   -6.707  36.445  1.000 28.809 0 172  ASN A CG  1 ? 
ATOM   1188 O  OD1 . ASN A  1 149 ? 2.234   -5.713  37.134  1.000 31.871 0 172  ASN A OD1 1 ? 
ATOM   1189 N  ND2 . ASN A  1 149 ? 3.228   -6.669  35.366  1.000 25.576 0 172  ASN A ND2 1 ? 
ATOM   1190 N  N   . MET A  1 150 ? 0.800   -7.696  33.541  1.000 21.862 0 173  MET A N   1 ? 
ATOM   1191 C  CA  . MET A  1 150 ? 0.905   -7.904  32.101  1.000 23.599 0 173  MET A CA  1 ? 
ATOM   1192 C  C   . MET A  1 150 ? 2.372   -8.020  31.662  1.000 25.625 0 173  MET A C   1 ? 
ATOM   1193 O  O   . MET A  1 150 ? 2.662   -8.741  30.708  1.000 21.998 0 173  MET A O   1 ? 
ATOM   1194 C  CB  . MET A  1 150 ? 0.271   -6.748  31.345  1.000 24.829 0 173  MET A CB  1 ? 
ATOM   1195 C  CG  . MET A  1 150 ? -1.182  -6.527  31.675  1.000 24.777 0 173  MET A CG  1 ? 
ATOM   1196 S  SD  . MET A  1 150 ? -2.244  -7.968  31.333  1.000 27.297 0 173  MET A SD  1 ? 
ATOM   1197 C  CE  . MET A  1 150 ? -2.201  -8.151  29.557  1.000 27.064 0 173  MET A CE  1 ? 
ATOM   1198 N  N   . GLY A  1 151 ? 3.245   -7.261  32.354  1.000 24.668 0 174  GLY A N   1 ? 
ATOM   1199 C  CA  . GLY A  1 151 ? 4.672   -7.136  32.075  1.000 26.160 0 174  GLY A CA  1 ? 
ATOM   1200 C  C   . GLY A  1 151 ? 5.535   -8.098  32.894  1.000 28.711 0 174  GLY A C   1 ? 
ATOM   1201 O  O   . GLY A  1 151 ? 6.611   -8.484  32.425  1.000 28.967 0 174  GLY A O   1 ? 
ATOM   1202 N  N   . GLY A  1 152 ? 5.060   -8.474  34.096  1.000 27.658 0 175  GLY A N   1 ? 
ATOM   1203 C  CA  . GLY A  1 152 ? 5.817   -9.226  35.095  1.000 27.319 0 175  GLY A CA  1 ? 
ATOM   1204 C  C   . GLY A  1 152 ? 5.568   -10.736 35.110  1.000 25.270 0 175  GLY A C   1 ? 
ATOM   1205 O  O   . GLY A  1 152 ? 6.395   -11.515 35.571  1.000 26.341 0 175  GLY A O   1 ? 
ATOM   1206 N  N   . GLY A  1 153 ? 4.424   -11.180 34.612  1.000 22.460 0 176  GLY A N   1 ? 
ATOM   1207 C  CA  . GLY A  1 153 ? 4.191   -12.605 34.436  1.000 21.783 0 176  GLY A CA  1 ? 
ATOM   1208 C  C   . GLY A  1 153 ? 3.166   -13.131 35.431  1.000 20.225 0 176  GLY A C   1 ? 
ATOM   1209 O  O   . GLY A  1 153 ? 2.507   -12.342 36.089  1.000 20.396 0 176  GLY A O   1 ? 
ATOM   1210 N  N   . THR A  1 154 ? 2.972   -14.460 35.406  1.000 19.360 0 177  THR A N   1 ? 
ATOM   1211 C  CA  . THR A  1 154 ? 2.004   -15.156 36.223  1.000 18.799 0 177  THR A CA  1 ? 
ATOM   1212 C  C   . THR A  1 154 ? 2.704   -15.699 37.466  1.000 20.574 0 177  THR A C   1 ? 
ATOM   1213 O  O   . THR A  1 154 ? 3.810   -16.253 37.380  1.000 20.583 0 177  THR A O   1 ? 
ATOM   1214 C  CB  . THR A  1 154 ? 1.368   -16.331 35.460  1.000 20.079 0 177  THR A CB  1 ? 
ATOM   1215 O  OG1 . THR A  1 154 ? 0.421   -15.824 34.505  1.000 19.541 0 177  THR A OG1 1 ? 
ATOM   1216 C  CG2 . THR A  1 154 ? 0.699   -17.364 36.360  1.000 18.419 0 177  THR A CG2 1 ? 
ATOM   1217 N  N   . LYS A  1 155 ? 2.047   -15.520 38.616  1.000 17.879 0 178  LYS A N   1 ? 
ATOM   1218 C  CA  . LYS A  1 155 ? 2.321   -16.272 39.829  1.000 18.437 0 178  LYS A CA  1 ? 
ATOM   1219 C  C   . LYS A  1 155 ? 1.012   -16.841 40.388  1.000 19.962 0 178  LYS A C   1 ? 
ATOM   1220 O  O   . LYS A  1 155 ? -0.022  -16.773 39.749  1.000 20.933 0 178  LYS A O   1 ? 
ATOM   1221 C  CB  . LYS A  1 155 ? 2.980   -15.316 40.809  1.000 19.230 0 178  LYS A CB  1 ? 
ATOM   1222 C  CG  . LYS A  1 155 ? 4.373   -14.876 40.412  1.000 23.947 0 178  LYS A CG  1 ? 
ATOM   1223 C  CD  . LYS A  1 155 ? 5.075   -14.240 41.587  1.000 30.868 0 178  LYS A CD  1 ? 
ATOM   1224 C  CE  . LYS A  1 155 ? 6.448   -13.701 41.270  1.000 40.316 0 178  LYS A CE  1 ? 
ATOM   1225 N  NZ  . LYS A  1 155 ? 7.064   -13.135 42.502  1.000 47.569 0 178  LYS A NZ  1 ? 
ATOM   1226 N  N   . PHE A  1 156 ? 1.054   -17.393 41.602  1.000 19.874 0 179  PHE A N   1 ? 
ATOM   1227 C  CA  . PHE A  1 156 ? -0.096  -18.076 42.138  1.000 20.525 0 179  PHE A CA  1 ? 
ATOM   1228 C  C   . PHE A  1 156 ? -0.324  -17.649 43.576  1.000 18.585 0 179  PHE A C   1 ? 
ATOM   1229 O  O   . PHE A  1 156 ? 0.596   -17.631 44.390  1.000 20.287 0 179  PHE A O   1 ? 
ATOM   1230 C  CB  . PHE A  1 156 ? 0.058   -19.598 42.006  1.000 20.914 0 179  PHE A CB  1 ? 
ATOM   1231 C  CG  . PHE A  1 156 ? 0.330   -20.029 40.586  1.000 19.008 0 179  PHE A CG  1 ? 
ATOM   1232 C  CD1 . PHE A  1 156 ? 1.610   -20.017 40.089  1.000 17.787 0 179  PHE A CD1 1 ? 
ATOM   1233 C  CD2 . PHE A  1 156 ? -0.728  -20.343 39.721  1.000 20.424 0 179  PHE A CD2 1 ? 
ATOM   1234 C  CE1 . PHE A  1 156 ? 1.855   -20.394 38.773  1.000 20.140 0 179  PHE A CE1 1 ? 
ATOM   1235 C  CE2 . PHE A  1 156 ? -0.478  -20.709 38.408  1.000 19.751 0 179  PHE A CE2 1 ? 
ATOM   1236 C  CZ  . PHE A  1 156 ? 0.814   -20.700 37.939  1.000 20.496 0 179  PHE A CZ  1 ? 
ATOM   1237 N  N   . HIS A  1 157 ? -1.590  -17.322 43.849  1.000 19.990 0 180  HIS A N   1 ? 
ATOM   1238 C  CA  . HIS A  1 157 ? -2.055  -17.164 45.216  1.000 19.761 0 180  HIS A CA  1 ? 
ATOM   1239 C  C   . HIS A  1 157 ? -2.376  -18.566 45.734  1.000 18.717 0 180  HIS A C   1 ? 
ATOM   1240 O  O   . HIS A  1 157 ? -3.089  -19.301 45.081  1.000 18.533 0 180  HIS A O   1 ? 
ATOM   1241 C  CB  . HIS A  1 157 ? -3.336  -16.330 45.236  1.000 19.983 0 180  HIS A CB  1 ? 
ATOM   1242 C  CG  . HIS A  1 157 ? -3.180  -14.935 44.715  1.000 19.663 0 180  HIS A CG  1 ? 
ATOM   1243 N  ND1 . HIS A  1 157 ? -2.315  -14.024 45.266  1.000 22.440 0 180  HIS A ND1 1 ? 
ATOM   1244 C  CD2 . HIS A  1 157 ? -3.887  -14.265 43.794  1.000 22.185 0 180  HIS A CD2 1 ? 
ATOM   1245 C  CE1 . HIS A  1 157 ? -2.470  -12.844 44.644  1.000 22.235 0 180  HIS A CE1 1 ? 
ATOM   1246 N  NE2 . HIS A  1 157 ? -3.425  -12.983 43.729  1.000 19.735 0 180  HIS A NE2 1 ? 
ATOM   1247 N  N   . ILE A  1 158 ? -1.851  -18.932 46.886  1.000 19.931 0 181  ILE A N   1 ? 
ATOM   1248 C  CA  . ILE A  1 158 ? -1.914  -20.297 47.394  1.000 19.183 0 181  ILE A CA  1 ? 
ATOM   1249 C  C   . ILE A  1 158 ? -2.505  -20.247 48.798  1.000 20.040 0 181  ILE A C   1 ? 
ATOM   1250 O  O   . ILE A  1 158 ? -2.003  -19.498 49.646  1.000 21.740 0 181  ILE A O   1 ? 
ATOM   1251 C  CB  . ILE A  1 158 ? -0.507  -20.918 47.443  1.000 21.331 0 181  ILE A CB  1 ? 
ATOM   1252 C  CG1 . ILE A  1 158 ? 0.164   -20.975 46.063  1.000 19.949 0 181  ILE A CG1 1 ? 
ATOM   1253 C  CG2 . ILE A  1 158 ? -0.553  -22.301 48.088  1.000 21.013 0 181  ILE A CG2 1 ? 
ATOM   1254 C  CD1 . ILE A  1 158 ? 1.593   -21.462 46.078  1.000 20.644 0 181  ILE A CD1 1 ? 
ATOM   1255 N  N   . SER A  1 159 ? -3.524  -21.070 49.037  1.000 20.665 0 182  SER A N   1 ? 
ATOM   1256 C  CA  . SER A  1 159 ? -4.052  -21.314 50.396  1.000 21.182 0 182  SER A CA  1 ? 
ATOM   1257 C  C   . SER A  1 159 ? -4.073  -22.819 50.724  1.000 21.843 0 182  SER A C   1 ? 
ATOM   1258 O  O   . SER A  1 159 ? -4.578  -23.642 49.941  1.000 21.480 0 182  SER A O   1 ? 
ATOM   1259 C  CB  . SER A  1 159 ? -5.455  -20.802 50.492  1.000 21.058 0 182  SER A CB  1 ? 
ATOM   1260 O  OG  . SER A  1 159 ? -6.004  -21.067 51.779  1.000 22.559 0 182  SER A OG  1 ? 
ATOM   1261 N  N   . ASP A  1 160 ? -3.616  -23.167 51.931  1.000 25.969 0 183  ASP A N   1 ? 
ATOM   1262 C  CA  . ASP A  1 160 ? -3.644  -24.550 52.394  1.000 26.906 0 183  ASP A CA  1 ? 
ATOM   1263 C  C   . ASP A  1 160 ? -4.746  -24.734 53.432  1.000 30.713 0 183  ASP A C   1 ? 
ATOM   1264 O  O   . ASP A  1 160 ? -4.806  -25.761 54.084  1.000 30.914 0 183  ASP A O   1 ? 
ATOM   1265 C  CB  . ASP A  1 160 ? -2.275  -24.940 52.962  1.000 27.677 0 183  ASP A CB  1 ? 
ATOM   1266 C  CG  . ASP A  1 160 ? -1.232  -25.052 51.868  1.000 30.271 0 183  ASP A CG  1 ? 
ATOM   1267 O  OD1 . ASP A  1 160 ? -1.529  -25.771 50.906  1.000 27.706 0 183  ASP A OD1 1 ? 
ATOM   1268 O  OD2 . ASP A  1 160 ? -0.196  -24.357 51.951  1.000 28.546 0 183  ASP A OD2 1 ? 
ATOM   1269 N  N   . ASP A  1 161 ? -5.645  -23.764 53.584  1.000 30.004 0 184  ASP A N   1 ? 
ATOM   1270 C  CA  . ASP A  1 161 ? -6.725  -23.925 54.549  1.000 30.023 0 184  ASP A CA  1 ? 
ATOM   1271 C  C   . ASP A  1 161 ? -8.071  -23.528 53.953  1.000 30.373 0 184  ASP A C   1 ? 
ATOM   1272 O  O   . ASP A  1 161 ? -8.907  -22.971 54.664  1.000 32.701 0 184  ASP A O   1 ? 
ATOM   1273 C  CB  . ASP A  1 161 ? -6.386  -23.178 55.844  1.000 31.723 0 184  ASP A CB  1 ? 
ATOM   1274 C  CG  . ASP A  1 161 ? -6.113  -21.706 55.638  1.000 29.556 0 184  ASP A CG  1 ? 
ATOM   1275 O  OD1 . ASP A  1 161 ? -6.389  -21.198 54.484  1.000 26.395 0 184  ASP A OD1 1 ? 
ATOM   1276 O  OD2 . ASP A  1 161 ? -5.565  -21.089 56.574  1.000 29.647 0 184  ASP A OD2 1 ? 
ATOM   1277 N  N   . GLY A  1 162 ? -8.303  -23.891 52.678  1.000 26.555 0 185  GLY A N   1 ? 
ATOM   1278 C  CA  . GLY A  1 162 ? -9.601  -23.725 52.039  1.000 27.697 0 185  GLY A CA  1 ? 
ATOM   1279 C  C   . GLY A  1 162 ? -9.915  -22.275 51.640  1.000 25.540 0 185  GLY A C   1 ? 
ATOM   1280 O  O   . GLY A  1 162 ? -11.038 -21.987 51.234  1.000 26.616 0 185  GLY A O   1 ? 
ATOM   1281 N  N   . GLY A  1 163 ? -8.913  -21.391 51.712  1.000 24.800 0 186  GLY A N   1 ? 
ATOM   1282 C  CA  . GLY A  1 163 ? -9.072  -19.994 51.313  1.000 23.726 0 186  GLY A CA  1 ? 
ATOM   1283 C  C   . GLY A  1 163 ? -9.054  -18.972 52.459  1.000 23.066 0 186  GLY A C   1 ? 
ATOM   1284 O  O   . GLY A  1 163 ? -9.243  -17.784 52.204  1.000 20.691 0 186  GLY A O   1 ? 
ATOM   1285 N  N   . LEU A  1 164 ? -8.755  -19.389 53.705  1.000 25.181 0 187  LEU A N   1 ? 
ATOM   1286 C  CA  . LEU A  1 164 ? -8.738  -18.472 54.844  1.000 23.363 0 187  LEU A CA  1 ? 
ATOM   1287 C  C   . LEU A  1 164 ? -7.472  -17.654 54.891  1.000 23.486 0 187  LEU A C   1 ? 
ATOM   1288 O  O   . LEU A  1 164 ? -7.538  -16.455 55.166  1.000 28.404 0 187  LEU A O   1 ? 
ATOM   1289 C  CB  . LEU A  1 164 ? -8.837  -19.251 56.164  1.000 27.880 0 187  LEU A CB  1 ? 
ATOM   1290 C  CG  . LEU A  1 164 ? -10.163 -19.927 56.460  1.000 32.342 0 187  LEU A CG  1 ? 
ATOM   1291 C  CD1 . LEU A  1 164 ? -10.030 -20.796 57.706  1.000 34.744 0 187  LEU A CD1 1 ? 
ATOM   1292 C  CD2 . LEU A  1 164 ? -11.271 -18.894 56.651  1.000 36.055 0 187  LEU A CD2 1 ? 
ATOM   1293 N  N   . THR A  1 165 ? -6.321  -18.296 54.663  1.000 22.010 0 188  THR A N   1 ? 
ATOM   1294 C  CA  . THR A  1 165 ? -5.040  -17.609 54.634  1.000 23.275 0 188  THR A CA  1 ? 
ATOM   1295 C  C   . THR A  1 165 ? -4.262  -17.939 53.360  1.000 22.062 0 188  THR A C   1 ? 
ATOM   1296 O  O   . THR A  1 165 ? -4.440  -19.003 52.787  1.000 25.279 0 188  THR A O   1 ? 
ATOM   1297 C  CB  . THR A  1 165 ? -4.193  -17.931 55.874  1.000 27.728 0 188  THR A CB  1 ? 
ATOM   1298 O  OG1 . THR A  1 165 ? -3.899  -19.318 55.825  1.000 25.479 0 188  THR A OG1 1 ? 
ATOM   1299 C  CG2 . THR A  1 165 ? -4.911  -17.577 57.160  1.000 28.933 0 188  THR A CG2 1 ? 
ATOM   1300 N  N   . TRP A  1 166 ? -3.456  -16.968 52.909  1.000 23.915 0 189  TRP A N   1 ? 
ATOM   1301 C  CA  . TRP A  1 166 ? -2.838  -17.016 51.590  1.000 25.497 0 189  TRP A CA  1 ? 
ATOM   1302 C  C   . TRP A  1 166 ? -1.351  -16.682 51.648  1.000 25.817 0 189  TRP A C   1 ? 
ATOM   1303 O  O   . TRP A  1 166 ? -0.945  -15.829 52.438  1.000 23.045 0 189  TRP A O   1 ? 
ATOM   1304 C  CB  . TRP A  1 166 ? -3.539  -16.011 50.666  1.000 22.370 0 189  TRP A CB  1 ? 
ATOM   1305 C  CG  . TRP A  1 166 ? -5.005  -16.301 50.486  1.000 22.273 0 189  TRP A CG  1 ? 
ATOM   1306 C  CD1 . TRP A  1 166 ? -6.066  -15.944 51.260  1.000 22.504 0 189  TRP A CD1 1 ? 
ATOM   1307 C  CD2 . TRP A  1 166 ? -5.533  -17.128 49.438  1.000 20.876 0 189  TRP A CD2 1 ? 
ATOM   1308 N  NE1 . TRP A  1 166 ? -7.225  -16.457 50.754  1.000 23.470 0 189  TRP A NE1 1 ? 
ATOM   1309 C  CE2 . TRP A  1 166 ? -6.923  -17.204 49.639  1.000 23.133 0 189  TRP A CE2 1 ? 
ATOM   1310 C  CE3 . TRP A  1 166 ? -4.944  -17.797 48.352  1.000 23.035 0 189  TRP A CE3 1 ? 
ATOM   1311 C  CZ2 . TRP A  1 166 ? -7.744  -17.909 48.781  1.000 23.031 0 189  TRP A CZ2 1 ? 
ATOM   1312 C  CZ3 . TRP A  1 166 ? -5.763  -18.508 47.504  1.000 21.517 0 189  TRP A CZ3 1 ? 
ATOM   1313 C  CH2 . TRP A  1 166 ? -7.140  -18.558 47.722  1.000 22.198 0 189  TRP A CH2 1 ? 
ATOM   1314 N  N   . HIS A  1 167 ? -0.605  -17.210 50.670  1.000 21.980 0 190  HIS A N   1 ? 
ATOM   1315 C  CA  . HIS A  1 167 ? 0.746   -16.757 50.341  1.000 23.780 0 190  HIS A CA  1 ? 
ATOM   1316 C  C   . HIS A  1 167 ? 0.925   -16.819 48.823  1.000 23.521 0 190  HIS A C   1 ? 
ATOM   1317 O  O   . HIS A  1 167 ? 0.035   -17.253 48.106  1.000 25.706 0 190  HIS A O   1 ? 
ATOM   1318 C  CB  . HIS A  1 167 ? 1.803   -17.582 51.085  1.000 24.402 0 190  HIS A CB  1 ? 
ATOM   1319 C  CG  . HIS A  1 167 ? 1.893   -19.020 50.700  1.000 25.456 0 190  HIS A CG  1 ? 
ATOM   1320 N  ND1 . HIS A  1 167 ? 1.096   -20.018 51.221  1.000 29.195 0 190  HIS A ND1 1 ? 
ATOM   1321 C  CD2 . HIS A  1 167 ? 2.746   -19.626 49.877  1.000 28.483 0 190  HIS A CD2 1 ? 
ATOM   1322 C  CE1 . HIS A  1 167 ? 1.449   -21.193 50.699  1.000 29.575 0 190  HIS A CE1 1 ? 
ATOM   1323 N  NE2 . HIS A  1 167 ? 2.434   -20.979 49.842  1.000 28.924 0 190  HIS A NE2 1 ? 
ATOM   1324 N  N   . VAL A  1 168 ? 2.048   -16.300 48.333  1.000 24.095 0 191  VAL A N   1 ? 
ATOM   1325 C  CA  . VAL A  1 168 ? 2.310   -16.250 46.903  1.000 23.238 0 191  VAL A CA  1 ? 
ATOM   1326 C  C   . VAL A  1 168 ? 3.382   -17.276 46.563  1.000 22.437 0 191  VAL A C   1 ? 
ATOM   1327 O  O   . VAL A  1 168 ? 4.293   -17.529 47.351  1.000 23.536 0 191  VAL A O   1 ? 
ATOM   1328 C  CB  . VAL A  1 168 ? 2.708   -14.835 46.468  1.000 23.199 0 191  VAL A CB  1 ? 
ATOM   1329 C  CG1 . VAL A  1 168 ? 3.000   -14.728 44.984  1.000 22.304 0 191  VAL A CG1 1 ? 
ATOM   1330 C  CG2 . VAL A  1 168 ? 1.609   -13.856 46.829  1.000 28.667 0 191  VAL A CG2 1 ? 
ATOM   1331 N  N   . SER A  1 169 ? 3.233   -17.917 45.402  1.000 21.335 0 192  SER A N   1 ? 
ATOM   1332 C  CA  . SER A  1 169 ? 4.295   -18.754 44.865  1.000 21.132 0 192  SER A CA  1 ? 
ATOM   1333 C  C   . SER A  1 169 ? 5.623   -17.985 44.798  1.000 21.244 0 192  SER A C   1 ? 
ATOM   1334 O  O   . SER A  1 169 ? 5.679   -16.747 44.657  1.000 21.358 0 192  SER A O   1 ? 
ATOM   1335 C  CB  . SER A  1 169 ? 3.905   -19.303 43.508  1.000 18.530 0 192  SER A CB  1 ? 
ATOM   1336 O  OG  . SER A  1 169 ? 3.727   -18.247 42.566  1.000 18.241 0 192  SER A OG  1 ? 
ATOM   1337 N  N   . ARG A  1 170 ? 6.721   -18.739 44.780  1.000 22.830 0 193  ARG A N   1 ? 
ATOM   1338 C  CA  . ARG A  1 170 ? 8.045   -18.142 44.736  1.000 25.814 0 193  ARG A CA  1 ? 
ATOM   1339 C  C   . ARG A  1 170 ? 8.337   -17.645 43.326  1.000 29.930 0 193  ARG A C   1 ? 
ATOM   1340 O  O   . ARG A  1 170 ? 9.020   -16.635 43.168  1.000 28.785 0 193  ARG A O   1 ? 
ATOM   1341 C  CB  . ARG A  1 170 ? 9.064   -19.133 45.322  1.000 31.181 0 193  ARG A CB  1 ? 
ATOM   1342 C  CG  . ARG A  1 170 ? 8.645   -19.792 46.642  1.000 33.776 0 193  ARG A CG  1 ? 
ATOM   1343 C  CD  . ARG A  1 170 ? 8.259   -18.804 47.733  1.000 41.989 0 193  ARG A CD  1 ? 
ATOM   1344 N  NE  . ARG A  1 170 ? 9.380   -17.913 48.018  1.000 52.621 0 193  ARG A NE  1 ? 
ATOM   1345 C  CZ  . ARG A  1 170 ? 9.335   -16.795 48.752  1.000 63.101 0 193  ARG A CZ  1 ? 
ATOM   1346 N  NH1 . ARG A  1 170 ? 10.471  -16.239 49.144  1.000 63.134 0 193  ARG A NH1 1 ? 
ATOM   1347 N  NH2 . ARG A  1 170 ? 8.181   -16.270 49.144  1.000 60.004 0 193  ARG A NH2 1 ? 
ATOM   1348 N  N   . ASN A  1 171 ? 7.761   -18.297 42.296  1.000 24.895 0 194  ASN A N   1 ? 
ATOM   1349 C  CA  . ASN A  1 171 ? 7.880   -17.856 40.922  1.000 25.122 0 194  ASN A CA  1 ? 
ATOM   1350 C  C   . ASN A  1 171 ? 6.650   -18.359 40.188  1.000 26.472 0 194  ASN A C   1 ? 
ATOM   1351 O  O   . ASN A  1 171 ? 5.672   -18.741 40.838  1.000 25.663 0 194  ASN A O   1 ? 
ATOM   1352 C  CB  . ASN A  1 171 ? 9.218   -18.270 40.282  1.000 26.364 0 194  ASN A CB  1 ? 
ATOM   1353 C  CG  . ASN A  1 171 ? 9.251   -19.743 39.966  1.000 25.250 0 194  ASN A CG  1 ? 
ATOM   1354 O  OD1 . ASN A  1 171 ? 8.559   -20.521 40.617  1.000 21.763 0 194  ASN A OD1 1 ? 
ATOM   1355 N  ND2 . ASN A  1 171 ? 10.016  -20.134 38.952  1.000 25.054 0 194  ASN A ND2 1 ? 
ATOM   1356 N  N   . GLY A  1 172 ? 6.665   -18.326 38.848  1.000 26.205 0 195  GLY A N   1 ? 
ATOM   1357 C  CA  . GLY A  1 172 ? 5.478   -18.691 38.100  1.000 24.951 0 195  GLY A CA  1 ? 
ATOM   1358 C  C   . GLY A  1 172 ? 5.767   -19.011 36.643  1.000 28.555 0 195  GLY A C   1 ? 
ATOM   1359 O  O   . GLY A  1 172 ? 6.513   -19.941 36.337  1.000 29.456 0 195  GLY A O   1 ? 
ATOM   1360 N  N   . VAL A  1 173 ? 5.123   -18.269 35.737  1.000 22.591 0 196  VAL A N   1 ? 
ATOM   1361 C  CA  . VAL A  1 173 ? 5.358   -18.481 34.330  1.000 20.596 0 196  VAL A CA  1 ? 
ATOM   1362 C  C   . VAL A  1 173 ? 5.700   -17.125 33.718  1.000 19.883 0 196  VAL A C   1 ? 
ATOM   1363 O  O   . VAL A  1 173 ? 5.067   -16.120 34.056  1.000 20.061 0 196  VAL A O   1 ? 
ATOM   1364 C  CB  . VAL A  1 173 ? 4.114   -19.078 33.657  1.000 21.583 0 196  VAL A CB  1 ? 
ATOM   1365 C  CG1 . VAL A  1 173 ? 4.452   -19.705 32.310  1.000 23.517 0 196  VAL A CG1 1 ? 
ATOM   1366 C  CG2 . VAL A  1 173 ? 3.437   -20.084 34.562  1.000 26.105 0 196  VAL A CG2 1 ? 
ATOM   1367 N  N   . THR A  1 174 ? 6.665   -17.142 32.798  1.000 19.999 0 197  THR A N   1 ? 
ATOM   1368 C  CA  . THR A  1 174 ? 7.043   -15.985 31.997  1.000 20.699 0 197  THR A CA  1 ? 
ATOM   1369 C  C   . THR A  1 174 ? 7.207   -16.438 30.556  1.000 21.532 0 197  THR A C   1 ? 
ATOM   1370 O  O   . THR A  1 174 ? 7.280   -17.638 30.272  1.000 20.207 0 197  THR A O   1 ? 
ATOM   1371 C  CB  . THR A  1 174 ? 8.320   -15.328 32.549  1.000 22.713 0 197  THR A CB  1 ? 
ATOM   1372 O  OG1 . THR A  1 174 ? 9.347   -16.327 32.611  1.000 21.496 0 197  THR A OG1 1 ? 
ATOM   1373 C  CG2 . THR A  1 174 ? 8.095   -14.705 33.908  1.000 24.758 0 197  THR A CG2 1 ? 
ATOM   1374 N  N   . SER A  1 175 ? 7.268   -15.465 29.652  1.000 19.017 0 198  SER A N   1 ? 
ATOM   1375 C  CA  . SER A  1 175 ? 7.446   -15.739 28.241  1.000 20.606 0 198  SER A CA  1 ? 
ATOM   1376 C  C   . SER A  1 175 ? 8.100   -14.524 27.605  1.000 20.647 0 198  SER A C   1 ? 
ATOM   1377 O  O   . SER A  1 175 ? 8.017   -13.399 28.121  1.000 21.595 0 198  SER A O   1 ? 
ATOM   1378 C  CB  . SER A  1 175 ? 6.130   -16.083 27.556  1.000 20.683 0 198  SER A CB  1 ? 
ATOM   1379 O  OG  . SER A  1 175 ? 5.225   -14.978 27.608  1.000 20.102 0 198  SER A OG  1 ? 
ATOM   1380 N  N   . PRO A  1 176 ? 8.821   -14.724 26.502  1.000 22.448 0 199  PRO A N   1 ? 
ATOM   1381 C  CA  . PRO A  1 176 ? 9.580   -13.628 25.903  1.000 23.476 0 199  PRO A CA  1 ? 
ATOM   1382 C  C   . PRO A  1 176 ? 8.756   -12.621 25.107  1.000 25.151 0 199  PRO A C   1 ? 
ATOM   1383 O  O   . PRO A  1 176 ? 7.690   -12.951 24.590  1.000 20.885 0 199  PRO A O   1 ? 
ATOM   1384 C  CB  . PRO A  1 176 ? 10.591  -14.328 24.979  1.000 27.425 0 199  PRO A CB  1 ? 
ATOM   1385 C  CG  . PRO A  1 176 ? 10.106  -15.735 24.802  1.000 26.920 0 199  PRO A CG  1 ? 
ATOM   1386 C  CD  . PRO A  1 176 ? 9.114   -16.033 25.914  1.000 24.801 0 199  PRO A CD  1 ? 
ATOM   1387 N  N   . ARG A  1 177 ? 9.289   -11.399 25.023  1.000 22.868 0 200  ARG A N   1 ? 
ATOM   1388 C  CA  . ARG A  1 177 ? 8.805   -10.393 24.088  1.000 23.653 0 200  ARG A CA  1 ? 
ATOM   1389 C  C   . ARG A  1 177 ? 8.860   -10.890 22.645  1.000 22.809 0 200  ARG A C   1 ? 
ATOM   1390 O  O   . ARG A  1 177 ? 9.716   -11.699 22.245  1.000 19.037 0 200  ARG A O   1 ? 
ATOM   1391 C  CB  . ARG A  1 177 ? 9.630   -9.108  24.228  1.000 21.872 0 200  ARG A CB  1 ? 
ATOM   1392 C  CG  . ARG A  1 177 ? 9.439   -8.395  25.551  1.000 24.060 0 200  ARG A CG  1 ? 
ATOM   1393 C  CD  . ARG A  1 177 ? 10.464  -7.287  25.707  1.000 26.436 0 200  ARG A CD  1 ? 
ATOM   1394 N  NE  . ARG A  1 177 ? 10.267  -6.484  26.911  1.000 28.361 0 200  ARG A NE  1 ? 
ATOM   1395 C  CZ  . ARG A  1 177 ? 9.264   -5.633  27.123  1.000 33.793 0 200  ARG A CZ  1 ? 
ATOM   1396 N  NH1 . ARG A  1 177 ? 8.472   -5.235  26.132  1.000 31.586 0 200  ARG A NH1 1 ? 
ATOM   1397 N  NH2 . ARG A  1 177 ? 9.108   -5.133  28.340  1.000 31.888 0 200  ARG A NH2 1 ? 
ATOM   1398 N  N   . HIS A  1 178 ? 7.947   -10.334 21.850  1.000 20.973 0 201  HIS A N   1 ? 
ATOM   1399 C  CA  . HIS A  1 178 ? 7.883   -10.581 20.424  1.000 22.473 0 201  HIS A CA  1 ? 
ATOM   1400 C  C   . HIS A  1 178 ? 8.920   -9.683  19.756  1.000 24.842 0 201  HIS A C   1 ? 
ATOM   1401 O  O   . HIS A  1 178 ? 9.145   -8.558  20.205  1.000 24.504 0 201  HIS A O   1 ? 
ATOM   1402 C  CB  . HIS A  1 178 ? 6.478   -10.273 19.886  1.000 21.459 0 201  HIS A CB  1 ? 
ATOM   1403 C  CG  . HIS A  1 178 ? 6.337   -10.340 18.404  1.000 22.760 0 201  HIS A CG  1 ? 
ATOM   1404 N  ND1 . HIS A  1 178 ? 6.084   -9.242  17.602  1.000 19.202 0 201  HIS A ND1 1 ? 
ATOM   1405 C  CD2 . HIS A  1 178 ? 6.453   -11.390 17.576  1.000 23.448 0 201  HIS A CD2 1 ? 
ATOM   1406 C  CE1 . HIS A  1 178 ? 6.050   -9.643  16.351  1.000 21.082 0 201  HIS A CE1 1 ? 
ATOM   1407 N  NE2 . HIS A  1 178 ? 6.283   -10.941 16.314  1.000 21.943 0 201  HIS A NE2 1 ? 
ATOM   1408 N  N   . GLU A  1 179 ? 9.513   -10.188 18.674  1.000 29.087 0 202  GLU A N   1 ? 
ATOM   1409 C  CA  . GLU A  1 179 ? 10.452  -9.422  17.842  1.000 28.501 0 202  GLU A CA  1 ? 
ATOM   1410 C  C   . GLU A  1 179 ? 9.847   -9.147  16.466  1.000 29.566 0 202  GLU A C   1 ? 
ATOM   1411 O  O   . GLU A  1 179 ? 9.284   -10.032 15.820  1.000 32.890 0 202  GLU A O   1 ? 
ATOM   1412 C  CB  . GLU A  1 179 ? 11.729  -10.225 17.658  1.000 29.901 0 202  GLU A CB  1 ? 
ATOM   1413 C  CG  . GLU A  1 179 ? 12.394  -10.612 18.973  1.000 34.071 0 202  GLU A CG  1 ? 
ATOM   1414 C  CD  . GLU A  1 179 ? 13.740  -11.308 18.820  1.000 42.341 0 202  GLU A CD  1 ? 
ATOM   1415 O  OE1 . GLU A  1 179 ? 14.187  -11.480 17.687  1.000 47.361 0 202  GLU A OE1 1 ? 
ATOM   1416 O  OE2 . GLU A  1 179 ? 14.311  -11.734 19.832  1.000 46.621 0 202  GLU A OE2 1 ? 
ATOM   1417 N  N   . ALA A  1 180 ? 9.992   -7.910  16.006  1.000 30.064 0 203  ALA A N   1 ? 
ATOM   1418 C  CA  . ALA A  1 180 ? 9.489   -7.494  14.710  1.000 31.526 0 203  ALA A CA  1 ? 
ATOM   1419 C  C   . ALA A  1 180 ? 10.401  -7.984  13.579  1.000 31.348 0 203  ALA A C   1 ? 
ATOM   1420 O  O   . ALA A  1 180 ? 10.872  -7.178  12.779  1.000 40.523 0 203  ALA A O   1 ? 
ATOM   1421 C  CB  . ALA A  1 180 ? 9.371   -5.978  14.688  1.000 32.129 0 203  ALA A CB  1 ? 
ATOM   1422 N  N   . ARG A  1 181 ? 10.611  -9.295  13.457  1.000 25.525 0 204  ARG A N   1 ? 
ATOM   1423 C  CA  . ARG A  1 181 ? 11.249  -9.845  12.272  1.000 23.953 0 204  ARG A CA  1 ? 
ATOM   1424 C  C   . ARG A  1 181 ? 10.221  -10.054 11.151  1.000 25.314 0 204  ARG A C   1 ? 
ATOM   1425 O  O   . ARG A  1 181 ? 9.031   -10.318 11.415  1.000 22.529 0 204  ARG A O   1 ? 
ATOM   1426 C  CB  . ARG A  1 181 ? 11.839  -11.199 12.624  1.000 24.263 0 204  ARG A CB  1 ? 
ATOM   1427 C  CG  . ARG A  1 181 ? 13.017  -11.151 13.590  1.000 29.011 0 204  ARG A CG  1 ? 
ATOM   1428 C  CD  . ARG A  1 181 ? 13.340  -12.566 14.070  1.000 29.460 0 204  ARG A CD  1 ? 
ATOM   1429 N  NE  . ARG A  1 181 ? 14.343  -12.452 15.120  1.000 34.540 0 204  ARG A NE  1 ? 
ATOM   1430 C  CZ  . ARG A  1 181 ? 15.624  -12.180 14.914  1.000 35.538 0 204  ARG A CZ  1 ? 
ATOM   1431 N  NH1 . ARG A  1 181 ? 16.170  -12.373 13.718  1.000 36.770 0 204  ARG A NH1 1 ? 
ATOM   1432 N  NH2 . ARG A  1 181 ? 16.389  -11.845 15.941  1.000 32.715 0 204  ARG A NH2 1 ? 
ATOM   1433 N  N   . PRO A  1 182 ? 10.634  -10.017 9.872   1.000 24.206 0 205  PRO A N   1 ? 
ATOM   1434 C  CA  . PRO A  1 182 ? 9.718   -10.310 8.765   1.000 24.930 0 205  PRO A CA  1 ? 
ATOM   1435 C  C   . PRO A  1 182 ? 8.969   -11.608 9.031   1.000 22.251 0 205  PRO A C   1 ? 
ATOM   1436 O  O   . PRO A  1 182 ? 9.533   -12.615 9.540   1.000 21.628 0 205  PRO A O   1 ? 
ATOM   1437 C  CB  . PRO A  1 182 ? 10.642  -10.385 7.519   1.000 27.850 0 205  PRO A CB  1 ? 
ATOM   1438 C  CG  . PRO A  1 182 ? 11.801  -9.439  7.877   1.000 26.289 0 205  PRO A CG  1 ? 
ATOM   1439 C  CD  . PRO A  1 182 ? 11.989  -9.657  9.376   1.000 26.919 0 205  PRO A CD  1 ? 
ATOM   1440 N  N   . PRO A  1 183 ? 7.661   -11.656 8.692   1.000 22.533 0 206  PRO A N   1 ? 
ATOM   1441 C  CA  . PRO A  1 183 ? 6.957   -10.602 7.951   1.000 22.318 0 206  PRO A CA  1 ? 
ATOM   1442 C  C   . PRO A  1 183 ? 6.333   -9.461  8.761   1.000 21.284 0 206  PRO A C   1 ? 
ATOM   1443 O  O   . PRO A  1 183 ? 5.663   -8.589  8.213   1.000 21.562 0 206  PRO A O   1 ? 
ATOM   1444 C  CB  . PRO A  1 183 ? 5.845   -11.413 7.300   1.000 23.805 0 206  PRO A CB  1 ? 
ATOM   1445 C  CG  . PRO A  1 183 ? 5.494   -12.474 8.312   1.000 24.151 0 206  PRO A CG  1 ? 
ATOM   1446 C  CD  . PRO A  1 183 ? 6.835   -12.855 8.915   1.000 24.248 0 206  PRO A CD  1 ? 
ATOM   1447 N  N   . HIS A  1 184 ? 6.613   -9.426  10.058  1.000 21.013 0 207  HIS A N   1 ? 
ATOM   1448 C  CA  . HIS A  1 184 ? 6.120   -8.349  10.913  1.000 21.063 0 207  HIS A CA  1 ? 
ATOM   1449 C  C   . HIS A  1 184 ? 6.781   -7.029  10.542  1.000 24.414 0 207  HIS A C   1 ? 
ATOM   1450 O  O   . HIS A  1 184 ? 7.985   -6.985  10.222  1.000 22.306 0 207  HIS A O   1 ? 
ATOM   1451 C  CB  . HIS A  1 184 ? 6.359   -8.679  12.375  1.000 21.567 0 207  HIS A CB  1 ? 
ATOM   1452 C  CG  . HIS A  1 184 ? 5.637   -9.877  12.855  1.000 21.672 0 207  HIS A CG  1 ? 
ATOM   1453 N  ND1 . HIS A  1 184 ? 4.271   -9.891  13.073  1.000 19.684 0 207  HIS A ND1 1 ? 
ATOM   1454 C  CD2 . HIS A  1 184 ? 6.097   -11.091 13.165  1.000 23.386 0 207  HIS A CD2 1 ? 
ATOM   1455 C  CE1 . HIS A  1 184 ? 3.920   -11.091 13.458  1.000 21.323 0 207  HIS A CE1 1 ? 
ATOM   1456 N  NE2 . HIS A  1 184 ? 5.003   -11.855 13.530  1.000 21.056 0 207  HIS A NE2 1 ? 
ATOM   1457 N  N   . GLN A  1 185 ? 5.990   -5.951  10.613  1.000 22.727 0 208  GLN A N   1 ? 
ATOM   1458 C  CA  . GLN A  1 185 ? 6.536   -4.609  10.456  1.000 23.478 0 208  GLN A CA  1 ? 
ATOM   1459 C  C   . GLN A  1 185 ? 6.552   -3.845  11.775  1.000 24.921 0 208  GLN A C   1 ? 
ATOM   1460 O  O   . GLN A  1 185 ? 6.776   -2.628  11.799  1.000 24.703 0 208  GLN A O   1 ? 
ATOM   1461 C  CB  . GLN A  1 185 ? 5.741   -3.882  9.376   1.000 23.499 0 208  GLN A CB  1 ? 
ATOM   1462 C  CG  . GLN A  1 185 ? 5.840   -4.524  8.006   1.000 23.674 0 208  GLN A CG  1 ? 
ATOM   1463 C  CD  . GLN A  1 185 ? 5.073   -3.684  7.023   1.000 24.689 0 208  GLN A CD  1 ? 
ATOM   1464 O  OE1 . GLN A  1 185 ? 5.449   -2.560  6.696   1.000 27.203 0 208  GLN A OE1 1 ? 
ATOM   1465 N  NE2 . GLN A  1 185 ? 3.898   -4.164  6.660   1.000 24.723 0 208  GLN A NE2 1 ? 
ATOM   1466 N  N   . GLY A  1 186 ? 6.271   -4.544  12.882  1.000 20.720 0 209  GLY A N   1 ? 
ATOM   1467 C  CA  . GLY A  1 186 ? 6.210   -3.902  14.176  1.000 22.411 0 209  GLY A CA  1 ? 
ATOM   1468 C  C   . GLY A  1 186 ? 6.036   -4.978  15.243  1.000 20.848 0 209  GLY A C   1 ? 
ATOM   1469 O  O   . GLY A  1 186 ? 5.962   -6.150  14.917  1.000 22.402 0 209  GLY A O   1 ? 
ATOM   1470 N  N   . VAL A  1 187 ? 5.900   -4.559  16.487  1.000 21.259 0 210  VAL A N   1 ? 
ATOM   1471 C  CA  . VAL A  1 187 ? 5.906   -5.486  17.609  1.000 22.094 0 210  VAL A CA  1 ? 
ATOM   1472 C  C   . VAL A  1 187 ? 4.482   -5.773  18.101  1.000 21.161 0 210  VAL A C   1 ? 
ATOM   1473 O  O   . VAL A  1 187 ? 3.678   -4.874  18.318  1.000 23.392 0 210  VAL A O   1 ? 
ATOM   1474 C  CB  . VAL A  1 187 ? 6.801   -4.961  18.733  1.000 21.706 0 210  VAL A CB  1 ? 
ATOM   1475 C  CG1 . VAL A  1 187 ? 6.908   -5.994  19.853  1.000 22.275 0 210  VAL A CG1 1 ? 
ATOM   1476 C  CG2 . VAL A  1 187 ? 8.187   -4.588  18.223  1.000 24.348 0 210  VAL A CG2 1 ? 
ATOM   1477 N  N   . ARG A  1 188 ? 4.206   -7.061  18.370  1.000 21.295 0 211  ARG A N   1 ? 
ATOM   1478 C  CA  . ARG A  1 188 ? 2.972   -7.463  19.060  1.000 20.279 0 211  ARG A CA  1 ? 
ATOM   1479 C  C   . ARG A  1 188 ? 2.974   -6.944  20.504  1.000 20.212 0 211  ARG A C   1 ? 
ATOM   1480 O  O   . ARG A  1 188 ? 4.013   -6.873  21.169  1.000 20.337 0 211  ARG A O   1 ? 
ATOM   1481 C  CB  . ARG A  1 188 ? 2.802   -8.987  19.125  1.000 19.263 0 211  ARG A CB  1 ? 
ATOM   1482 C  CG  . ARG A  1 188 ? 2.639   -9.691  17.770  1.000 18.159 0 211  ARG A CG  1 ? 
ATOM   1483 C  CD  . ARG A  1 188 ? 2.647   -11.176 18.028  1.000 18.327 0 211  ARG A CD  1 ? 
ATOM   1484 N  NE  . ARG A  1 188 ? 2.387   -11.937 16.819  1.000 19.119 0 211  ARG A NE  1 ? 
ATOM   1485 C  CZ  . ARG A  1 188 ? 2.782   -13.179 16.622  1.000 18.999 0 211  ARG A CZ  1 ? 
ATOM   1486 N  NH1 . ARG A  1 188 ? 3.475   -13.828 17.546  1.000 20.834 0 211  ARG A NH1 1 ? 
ATOM   1487 N  NH2 . ARG A  1 188 ? 2.530   -13.754 15.473  1.000 19.594 0 211  ARG A NH2 1 ? 
ATOM   1488 N  N   . TRP A  1 189 ? 1.772   -6.606  20.978  1.000 18.874 0 212  TRP A N   1 ? 
ATOM   1489 C  CA  . TRP A  1 189 ? 1.536   -6.295  22.369  1.000 19.234 0 212  TRP A CA  1 ? 
ATOM   1490 C  C   . TRP A  1 189 ? 2.263   -7.325  23.213  1.000 20.275 0 212  TRP A C   1 ? 
ATOM   1491 O  O   . TRP A  1 189 ? 2.083   -8.523  22.957  1.000 19.925 0 212  TRP A O   1 ? 
ATOM   1492 C  CB  . TRP A  1 189 ? 0.029   -6.384  22.636  1.000 18.419 0 212  TRP A CB  1 ? 
ATOM   1493 C  CG  . TRP A  1 189 ? -0.427  -5.974  24.003  1.000 19.817 0 212  TRP A CG  1 ? 
ATOM   1494 C  CD1 . TRP A  1 189 ? 0.193   -5.176  24.911  1.000 19.711 0 212  TRP A CD1 1 ? 
ATOM   1495 C  CD2 . TRP A  1 189 ? -1.697  -6.316  24.568  1.000 18.011 0 212  TRP A CD2 1 ? 
ATOM   1496 N  NE1 . TRP A  1 189 ? -0.587  -4.993  26.015  1.000 18.570 0 212  TRP A NE1 1 ? 
ATOM   1497 C  CE2 . TRP A  1 189 ? -1.767  -5.665  25.825  1.000 18.335 0 212  TRP A CE2 1 ? 
ATOM   1498 C  CE3 . TRP A  1 189 ? -2.768  -7.081  24.125  1.000 19.426 0 212  TRP A CE3 1 ? 
ATOM   1499 C  CZ2 . TRP A  1 189 ? -2.867  -5.801  26.653  1.000 19.325 0 212  TRP A CZ2 1 ? 
ATOM   1500 C  CZ3 . TRP A  1 189 ? -3.878  -7.201  24.943  1.000 20.719 0 212  TRP A CZ3 1 ? 
ATOM   1501 C  CH2 . TRP A  1 189 ? -3.924  -6.544  26.184  1.000 20.542 0 212  TRP A CH2 1 ? 
ATOM   1502 N  N   . PHE A  1 190 ? 3.034   -6.850  24.202  1.000 19.711 0 213  PHE A N   1 ? 
ATOM   1503 C  CA  . PHE A  1 190 ? 3.763   -7.753  25.087  1.000 19.608 0 213  PHE A CA  1 ? 
ATOM   1504 C  C   . PHE A  1 190 ? 2.823   -8.202  26.199  1.000 19.246 0 213  PHE A C   1 ? 
ATOM   1505 O  O   . PHE A  1 190 ? 2.277   -7.389  26.956  1.000 20.954 0 213  PHE A O   1 ? 
ATOM   1506 C  CB  . PHE A  1 190 ? 5.007   -7.101  25.700  1.000 21.820 0 213  PHE A CB  1 ? 
ATOM   1507 C  CG  . PHE A  1 190 ? 5.757   -7.962  26.694  1.000 22.597 0 213  PHE A CG  1 ? 
ATOM   1508 C  CD1 . PHE A  1 190 ? 6.008   -9.301  26.428  1.000 23.939 0 213  PHE A CD1 1 ? 
ATOM   1509 C  CD2 . PHE A  1 190 ? 6.239   -7.434  27.887  1.000 24.602 0 213  PHE A CD2 1 ? 
ATOM   1510 C  CE1 . PHE A  1 190 ? 6.697   -10.096 27.334  1.000 25.795 0 213  PHE A CE1 1 ? 
ATOM   1511 C  CE2 . PHE A  1 190 ? 6.967   -8.224  28.769  1.000 25.708 0 213  PHE A CE2 1 ? 
ATOM   1512 C  CZ  . PHE A  1 190 ? 7.214   -9.552  28.477  1.000 22.228 0 213  PHE A CZ  1 ? 
ATOM   1513 N  N   . ASN A  1 191 ? 2.669   -9.516  26.307  1.000 17.274 0 214  ASN A N   1 ? 
ATOM   1514 C  CA  . ASN A  1 191 ? 2.043   -10.134 27.451  1.000 17.536 0 214  ASN A CA  1 ? 
ATOM   1515 C  C   . ASN A  1 191 ? 3.001   -11.187 27.974  1.000 17.900 0 214  ASN A C   1 ? 
ATOM   1516 O  O   . ASN A  1 191 ? 3.393   -12.086 27.237  1.000 19.736 0 214  ASN A O   1 ? 
ATOM   1517 C  CB  . ASN A  1 191 ? 0.717   -10.834 27.115  1.000 16.868 0 214  ASN A CB  1 ? 
ATOM   1518 C  CG  . ASN A  1 191 ? -0.480  -9.949  26.801  1.000 20.320 0 214  ASN A CG  1 ? 
ATOM   1519 O  OD1 . ASN A  1 191 ? -1.598  -10.466 26.651  1.000 19.502 0 214  ASN A OD1 1 ? 
ATOM   1520 N  ND2 . ASN A  1 191 ? -0.287  -8.644  26.670  1.000 20.896 0 214  ASN A ND2 1 ? 
ATOM   1521 N  N   . ASN A  1 192 ? 3.337   -11.097 29.262  1.000 18.206 0 215  ASN A N   1 ? 
ATOM   1522 C  CA  . ASN A  1 192 ? 4.322   -11.995 29.854  1.000 18.529 0 215  ASN A CA  1 ? 
ATOM   1523 C  C   . ASN A  1 192 ? 3.582   -13.168 30.506  1.000 17.232 0 215  ASN A C   1 ? 
ATOM   1524 O  O   . ASN A  1 192 ? 3.088   -13.069 31.616  1.000 21.896 0 215  ASN A O   1 ? 
ATOM   1525 C  CB  . ASN A  1 192 ? 5.177   -11.210 30.839  1.000 18.349 0 215  ASN A CB  1 ? 
ATOM   1526 C  CG  . ASN A  1 192 ? 6.390   -11.963 31.335  1.000 20.888 0 215  ASN A CG  1 ? 
ATOM   1527 O  OD1 . ASN A  1 192 ? 6.552   -13.143 31.066  1.000 21.965 0 215  ASN A OD1 1 ? 
ATOM   1528 N  ND2 . ASN A  1 192 ? 7.279   -11.267 32.019  1.000 21.512 0 215  ASN A ND2 1 ? 
ATOM   1529 N  N   . ALA A  1 193 ? 3.388   -14.245 29.737  1.000 17.719 0 216  ALA A N   1 ? 
ATOM   1530 C  CA  . ALA A  1 193 ? 2.748   -15.475 30.175  1.000 17.821 0 216  ALA A CA  1 ? 
ATOM   1531 C  C   . ALA A  1 193 ? 1.578   -15.188 31.110  1.000 18.481 0 216  ALA A C   1 ? 
ATOM   1532 O  O   . ALA A  1 193 ? 1.606   -15.585 32.253  1.000 19.575 0 216  ALA A O   1 ? 
ATOM   1533 C  CB  . ALA A  1 193 ? 3.782   -16.386 30.809  1.000 18.655 0 216  ALA A CB  1 ? 
ATOM   1534 N  N   . VAL A  1 194 ? 0.516   -14.584 30.566  1.000 17.516 0 217  VAL A N   1 ? 
ATOM   1535 C  CA  . VAL A  1 194 ? -0.652  -14.167 31.334  1.000 18.115 0 217  VAL A CA  1 ? 
ATOM   1536 C  C   . VAL A  1 194 ? -1.787  -15.173 31.192  1.000 16.876 0 217  VAL A C   1 ? 
ATOM   1537 O  O   . VAL A  1 194 ? -1.740  -16.098 30.381  1.000 16.566 0 217  VAL A O   1 ? 
ATOM   1538 C  CB  . VAL A  1 194 ? -1.121  -12.759 30.890  1.000 17.520 0 217  VAL A CB  1 ? 
ATOM   1539 C  CG1 . VAL A  1 194 ? -0.022  -11.705 30.994  1.000 18.393 0 217  VAL A CG1 1 ? 
ATOM   1540 C  CG2 . VAL A  1 194 ? -1.679  -12.791 29.484  1.000 19.344 0 217  VAL A CG2 1 ? 
ATOM   1541 N  N   . GLU A  1 195 ? -2.817  -14.996 32.027  1.000 17.193 0 218  GLU A N   1 ? 
ATOM   1542 C  CA  . GLU A  1 195 ? -4.088  -15.705 31.860  1.000 18.000 0 218  GLU A CA  1 ? 
ATOM   1543 C  C   . GLU A  1 195 ? -3.873  -17.224 31.849  1.000 17.440 0 218  GLU A C   1 ? 
ATOM   1544 O  O   . GLU A  1 195 ? -4.319  -17.932 30.932  1.000 19.478 0 218  GLU A O   1 ? 
ATOM   1545 C  CB  . GLU A  1 195 ? -4.746  -15.297 30.549  1.000 20.330 0 218  GLU A CB  1 ? 
ATOM   1546 C  CG  . GLU A  1 195 ? -5.080  -13.807 30.470  1.000 23.640 0 218  GLU A CG  1 ? 
ATOM   1547 C  CD  . GLU A  1 195 ? -6.445  -13.388 30.973  1.000 26.379 0 218  GLU A CD  1 ? 
ATOM   1548 O  OE1 . GLU A  1 195 ? -6.650  -12.155 31.101  1.000 27.676 0 218  GLU A OE1 1 ? 
ATOM   1549 O  OE2 . GLU A  1 195 ? -7.301  -14.259 31.250  1.000 27.493 0 218  GLU A OE2 1 ? 
ATOM   1550 N  N   . ALA A  1 196 ? -3.135  -17.722 32.849  1.000 16.987 0 219  ALA A N   1 ? 
ATOM   1551 C  CA  . ALA A  1 196 ? -2.820  -19.142 32.891  1.000 16.725 0 219  ALA A CA  1 ? 
ATOM   1552 C  C   . ALA A  1 196 ? -4.018  -19.993 33.260  1.000 16.282 0 219  ALA A C   1 ? 
ATOM   1553 O  O   . ALA A  1 196 ? -4.883  -19.613 34.039  1.000 17.416 0 219  ALA A O   1 ? 
ATOM   1554 C  CB  . ALA A  1 196 ? -1.675  -19.419 33.826  1.000 19.006 0 219  ALA A CB  1 ? 
ATOM   1555 N  N   . THR A  1 197 ? -4.010  -21.218 32.708  1.000 15.864 0 220  THR A N   1 ? 
ATOM   1556 C  CA  . THR A  1 197 ? -4.874  -22.302 33.117  1.000 17.564 0 220  THR A CA  1 ? 
ATOM   1557 C  C   . THR A  1 197 ? -3.951  -23.377 33.712  1.000 18.741 0 220  THR A C   1 ? 
ATOM   1558 O  O   . THR A  1 197 ? -2.799  -23.513 33.291  1.000 18.624 0 220  THR A O   1 ? 
ATOM   1559 C  CB  . THR A  1 197 ? -5.738  -22.823 31.957  1.000 16.395 0 220  THR A CB  1 ? 
ATOM   1560 O  OG1 . THR A  1 197 ? -6.639  -23.827 32.430  1.000 15.382 0 220  THR A OG1 1 ? 
ATOM   1561 C  CG2 . THR A  1 197 ? -4.941  -23.412 30.812  1.000 18.512 0 220  THR A CG2 1 ? 
ATOM   1562 N  N   . VAL A  1 198 ? -4.420  -24.058 34.753  1.000 18.115 0 221  VAL A N   1 ? 
ATOM   1563 C  CA  . VAL A  1 198 ? -3.589  -25.028 35.436  1.000 19.435 0 221  VAL A CA  1 ? 
ATOM   1564 C  C   . VAL A  1 198 ? -4.341  -26.341 35.494  1.000 19.215 0 221  VAL A C   1 ? 
ATOM   1565 O  O   . VAL A  1 198 ? -5.528  -26.379 35.832  1.000 18.874 0 221  VAL A O   1 ? 
ATOM   1566 C  CB  . VAL A  1 198 ? -3.205  -24.549 36.837  1.000 19.308 0 221  VAL A CB  1 ? 
ATOM   1567 C  CG1 . VAL A  1 198 ? -2.534  -25.661 37.606  1.000 20.478 0 221  VAL A CG1 1 ? 
ATOM   1568 C  CG2 . VAL A  1 198 ? -2.328  -23.319 36.815  1.000 18.907 0 221  VAL A CG2 1 ? 
ATOM   1569 N  N   . LEU A  1 199 ? -3.604  -27.424 35.195  1.000 18.904 0 222  LEU A N   1 ? 
ATOM   1570 C  CA  . LEU A  1 199 ? -4.108  -28.776 35.386  1.000 18.935 0 222  LEU A CA  1 ? 
ATOM   1571 C  C   . LEU A  1 199 ? -3.155  -29.584 36.264  1.000 18.411 0 222  LEU A C   1 ? 
ATOM   1572 O  O   . LEU A  1 199 ? -1.929  -29.587 36.083  1.000 19.107 0 222  LEU A O   1 ? 
ATOM   1573 C  CB  . LEU A  1 199 ? -4.243  -29.430 34.014  1.000 21.044 0 222  LEU A CB  1 ? 
ATOM   1574 C  CG  . LEU A  1 199 ? -4.931  -30.781 33.984  1.000 23.154 0 222  LEU A CG  1 ? 
ATOM   1575 C  CD1 . LEU A  1 199 ? -6.425  -30.622 34.123  1.000 23.572 0 222  LEU A CD1 1 ? 
ATOM   1576 C  CD2 . LEU A  1 199 ? -4.575  -31.505 32.688  1.000 26.146 0 222  LEU A CD2 1 ? 
ATOM   1577 N  N   . GLU A  1 200 ? -3.756  -30.327 37.180  1.000 19.645 0 223  GLU A N   1 ? 
ATOM   1578 C  CA  . GLU A  1 200 ? -3.019  -31.333 37.941  1.000 19.952 0 223  GLU A CA  1 ? 
ATOM   1579 C  C   . GLU A  1 200 ? -2.968  -32.617 37.134  1.000 19.475 0 223  GLU A C   1 ? 
ATOM   1580 O  O   . GLU A  1 200 ? -4.012  -33.186 36.807  1.000 21.541 0 223  GLU A O   1 ? 
ATOM   1581 C  CB  . GLU A  1 200 ? -3.722  -31.578 39.271  1.000 21.993 0 223  GLU A CB  1 ? 
ATOM   1582 C  CG  . GLU A  1 200 ? -2.918  -32.397 40.260  1.000 25.075 0 223  GLU A CG  1 ? 
ATOM   1583 C  CD  . GLU A  1 200 ? -3.589  -32.549 41.620  1.000 25.801 0 223  GLU A CD  1 ? 
ATOM   1584 O  OE1 . GLU A  1 200 ? -4.827  -32.393 41.730  1.000 28.886 0 223  GLU A OE1 1 ? 
ATOM   1585 O  OE2 . GLU A  1 200 ? -2.875  -32.897 42.536  1.000 30.767 0 223  GLU A OE2 1 ? 
ATOM   1586 N  N   . MET A  1 201 ? -1.747  -33.067 36.873  1.000 18.375 0 224  MET A N   1 ? 
ATOM   1587 C  CA  . MET A  1 201 ? -1.528  -34.302 36.151  1.000 20.254 0 224  MET A CA  1 ? 
ATOM   1588 C  C   . MET A  1 201 ? -1.753  -35.454 37.134  1.000 20.155 0 224  MET A C   1 ? 
ATOM   1589 O  O   . MET A  1 201 ? -1.808  -35.276 38.340  1.000 20.391 0 224  MET A O   1 ? 
ATOM   1590 C  CB  . MET A  1 201 ? -0.091  -34.343 35.620  1.000 21.317 0 224  MET A CB  1 ? 
ATOM   1591 C  CG  . MET A  1 201 ? 0.307   -33.154 34.732  1.000 23.583 0 224  MET A CG  1 ? 
ATOM   1592 S  SD  . MET A  1 201 ? -0.908  -32.754 33.449  1.000 27.353 0 224  MET A SD  1 ? 
ATOM   1593 C  CE  . MET A  1 201 ? -0.639  -34.143 32.348  1.000 29.291 0 224  MET A CE  1 ? 
ATOM   1594 N  N   . LYS A  1 202 ? -1.894  -36.665 36.607  1.000 21.190 0 225  LYS A N   1 ? 
ATOM   1595 C  CA  . LYS A  1 202 ? -2.179  -37.808 37.456  1.000 22.379 0 225  LYS A CA  1 ? 
ATOM   1596 C  C   . LYS A  1 202 ? -1.039  -38.066 38.440  1.000 23.920 0 225  LYS A C   1 ? 
ATOM   1597 O  O   . LYS A  1 202 ? -1.307  -38.558 39.538  1.000 22.978 0 225  LYS A O   1 ? 
ATOM   1598 C  CB  . LYS A  1 202 ? -2.506  -39.033 36.600  1.000 26.625 0 225  LYS A CB  1 ? 
ATOM   1599 C  CG  . LYS A  1 202 ? -3.956  -39.111 36.160  1.000 28.635 0 225  LYS A CG  1 ? 
ATOM   1600 C  CD  . LYS A  1 202 ? -4.251  -40.385 35.413  1.000 30.576 0 225  LYS A CD  1 ? 
ATOM   1601 C  CE  . LYS A  1 202 ? -5.680  -40.442 34.945  1.000 34.721 0 225  LYS A CE  1 ? 
ATOM   1602 N  NZ  . LYS A  1 202 ? -5.934  -41.703 34.215  1.000 36.716 0 225  LYS A NZ  1 ? 
ATOM   1603 N  N   . ASP A  1 203 ? 0.209   -37.720 38.113  1.000 22.275 0 226  ASP A N   1 ? 
ATOM   1604 C  CA  . ASP A  1 203 ? 1.277   -37.948 39.073  1.000 23.159 0 226  ASP A CA  1 ? 
ATOM   1605 C  C   . ASP A  1 203 ? 1.441   -36.809 40.071  1.000 24.486 0 226  ASP A C   1 ? 
ATOM   1606 O  O   . ASP A  1 203 ? 2.385   -36.842 40.841  1.000 25.004 0 226  ASP A O   1 ? 
ATOM   1607 C  CB  . ASP A  1 203 ? 2.634   -38.198 38.426  1.000 24.195 0 226  ASP A CB  1 ? 
ATOM   1608 C  CG  . ASP A  1 203 ? 3.238   -37.035 37.672  1.000 31.028 0 226  ASP A CG  1 ? 
ATOM   1609 O  OD1 . ASP A  1 203 ? 2.670   -35.909 37.705  1.000 29.047 0 226  ASP A OD1 1 ? 
ATOM   1610 O  OD2 . ASP A  1 203 ? 4.303   -37.262 37.081  1.000 29.931 0 226  ASP A OD2 1 ? 
ATOM   1611 N  N   . GLY A  1 204 ? 0.587   -35.779 40.008  1.000 23.130 0 227  GLY A N   1 ? 
ATOM   1612 C  CA  . GLY A  1 204 ? 0.710   -34.666 40.938  1.000 22.775 0 227  GLY A CA  1 ? 
ATOM   1613 C  C   . GLY A  1 204 ? 1.394   -33.438 40.374  1.000 23.573 0 227  GLY A C   1 ? 
ATOM   1614 O  O   . GLY A  1 204 ? 1.252   -32.355 40.940  1.000 24.659 0 227  GLY A O   1 ? 
ATOM   1615 N  N   . THR A  1 205 ? 2.129   -33.574 39.269  1.000 24.083 0 228  THR A N   1 ? 
ATOM   1616 C  CA  . THR A  1 205 ? 2.726   -32.397 38.631  1.000 22.713 0 228  THR A CA  1 ? 
ATOM   1617 C  C   . THR A  1 205 ? 1.609   -31.416 38.252  1.000 21.509 0 228  THR A C   1 ? 
ATOM   1618 O  O   . THR A  1 205 ? 0.557   -31.844 37.792  1.000 21.819 0 228  THR A O   1 ? 
ATOM   1619 C  CB  . THR A  1 205 ? 3.509   -32.829 37.384  1.000 23.642 0 228  THR A CB  1 ? 
ATOM   1620 O  OG1 . THR A  1 205 ? 4.477   -33.795 37.825  1.000 25.607 0 228  THR A OG1 1 ? 
ATOM   1621 C  CG2 . THR A  1 205 ? 4.209   -31.699 36.671  1.000 20.979 0 228  THR A CG2 1 ? 
ATOM   1622 N  N   . LEU A  1 206 ? 1.837   -30.112 38.435  1.000 21.774 0 229  LEU A N   1 ? 
ATOM   1623 C  CA  . LEU A  1 206 ? 0.949   -29.100 37.866  1.000 19.947 0 229  LEU A CA  1 ? 
ATOM   1624 C  C   . LEU A  1 206 ? 1.524   -28.593 36.546  1.000 18.599 0 229  LEU A C   1 ? 
ATOM   1625 O  O   . LEU A  1 206 ? 2.737   -28.366 36.411  1.000 21.416 0 229  LEU A O   1 ? 
ATOM   1626 C  CB  . LEU A  1 206 ? 0.787   -27.929 38.831  1.000 20.701 0 229  LEU A CB  1 ? 
ATOM   1627 C  CG  . LEU A  1 206 ? 0.326   -28.243 40.244  1.000 19.249 0 229  LEU A CG  1 ? 
ATOM   1628 C  CD1 . LEU A  1 206 ? 0.018   -26.916 40.932  1.000 21.537 0 229  LEU A CD1 1 ? 
ATOM   1629 C  CD2 . LEU A  1 206 ? -0.864  -29.185 40.308  1.000 22.452 0 229  LEU A CD2 1 ? 
ATOM   1630 N  N   . TRP A  1 207 ? 0.627   -28.457 35.578  1.000 18.701 0 230  TRP A N   1 ? 
ATOM   1631 C  CA  . TRP A  1 207 ? 0.947   -27.934 34.262  1.000 19.227 0 230  TRP A CA  1 ? 
ATOM   1632 C  C   . TRP A  1 207 ? 0.241   -26.600 34.125  1.000 19.195 0 230  TRP A C   1 ? 
ATOM   1633 O  O   . TRP A  1 207 ? -0.978  -26.560 34.262  1.000 19.520 0 230  TRP A O   1 ? 
ATOM   1634 C  CB  . TRP A  1 207 ? 0.480   -28.951 33.225  1.000 19.211 0 230  TRP A CB  1 ? 
ATOM   1635 C  CG  . TRP A  1 207 ? 0.542   -28.534 31.775  1.000 20.128 0 230  TRP A CG  1 ? 
ATOM   1636 C  CD1 . TRP A  1 207 ? 1.356   -27.609 31.200  1.000 19.828 0 230  TRP A CD1 1 ? 
ATOM   1637 C  CD2 . TRP A  1 207 ? -0.276  -29.073 30.716  1.000 18.788 0 230  TRP A CD2 1 ? 
ATOM   1638 N  NE1 . TRP A  1 207 ? 1.106   -27.530 29.858  1.000 20.858 0 230  TRP A NE1 1 ? 
ATOM   1639 C  CE2 . TRP A  1 207 ? 0.093   -28.394 29.535  1.000 20.159 0 230  TRP A CE2 1 ? 
ATOM   1640 C  CE3 . TRP A  1 207 ? -1.298  -30.023 30.661  1.000 20.809 0 230  TRP A CE3 1 ? 
ATOM   1641 C  CZ2 . TRP A  1 207 ? -0.497  -28.664 28.308  1.000 23.394 0 230  TRP A CZ2 1 ? 
ATOM   1642 C  CZ3 . TRP A  1 207 ? -1.891  -30.292 29.438  1.000 20.622 0 230  TRP A CZ3 1 ? 
ATOM   1643 C  CH2 . TRP A  1 207 ? -1.499  -29.613 28.284  1.000 20.416 0 230  TRP A CH2 1 ? 
ATOM   1644 N  N   . ALA A  1 208 ? 1.018   -25.543 33.897  1.000 19.513 0 231  ALA A N   1 ? 
ATOM   1645 C  CA  . ALA A  1 208 ? 0.470   -24.221 33.670  1.000 18.761 0 231  ALA A CA  1 ? 
ATOM   1646 C  C   . ALA A  1 208 ? 0.677   -23.858 32.204  1.000 19.041 0 231  ALA A C   1 ? 
ATOM   1647 O  O   . ALA A  1 208 ? 1.759   -24.044 31.655  1.000 18.546 0 231  ALA A O   1 ? 
ATOM   1648 C  CB  . ALA A  1 208 ? 1.112   -23.209 34.574  1.000 18.808 0 231  ALA A CB  1 ? 
ATOM   1649 N  N   . LEU A  1 209 ? -0.401  -23.400 31.564  1.000 18.498 0 232  LEU A N   1 ? 
ATOM   1650 C  CA  . LEU A  1 209 ? -0.384  -23.040 30.163  1.000 18.168 0 232  LEU A CA  1 ? 
ATOM   1651 C  C   . LEU A  1 209 ? -0.904  -21.613 30.051  1.000 17.922 0 232  LEU A C   1 ? 
ATOM   1652 O  O   . LEU A  1 209 ? -2.012  -21.371 30.520  1.000 18.612 0 232  LEU A O   1 ? 
ATOM   1653 C  CB  . LEU A  1 209 ? -1.297  -24.042 29.460  1.000 19.581 0 232  LEU A CB  1 ? 
ATOM   1654 C  CG  . LEU A  1 209 ? -1.370  -23.984 27.939  1.000 19.897 0 232  LEU A CG  1 ? 
ATOM   1655 C  CD1 . LEU A  1 209 ? -0.032  -24.261 27.315  1.000 21.957 0 232  LEU A CD1 1 ? 
ATOM   1656 C  CD2 . LEU A  1 209 ? -2.406  -24.985 27.465  1.000 21.377 0 232  LEU A CD2 1 ? 
ATOM   1657 N  N   . ALA A  1 210 ? -0.141  -20.732 29.376  1.000 16.719 0 233  ALA A N   1 ? 
ATOM   1658 C  CA  . ALA A  1 210 ? -0.362  -19.299 29.464  1.000 18.603 0 233  ALA A CA  1 ? 
ATOM   1659 C  C   . ALA A  1 210 ? -0.304  -18.647 28.078  1.000 17.712 0 233  ALA A C   1 ? 
ATOM   1660 O  O   . ALA A  1 210 ? 0.443   -19.070 27.190  1.000 18.753 0 233  ALA A O   1 ? 
ATOM   1661 C  CB  . ALA A  1 210 ? 0.667   -18.688 30.403  1.000 19.182 0 233  ALA A CB  1 ? 
ATOM   1662 N  N   . ARG A  1 211 ? -1.032  -17.539 27.995  1.000 17.948 0 234  ARG A N   1 ? 
ATOM   1663 C  CA  . ARG A  1 211 ? -1.119  -16.655 26.835  1.000 17.954 0 234  ARG A CA  1 ? 
ATOM   1664 C  C   . ARG A  1 211 ? 0.129   -15.785 26.698  1.000 18.271 0 234  ARG A C   1 ? 
ATOM   1665 O  O   . ARG A  1 211 ? 0.552   -15.152 27.682  1.000 16.272 0 234  ARG A O   1 ? 
ATOM   1666 C  CB  . ARG A  1 211 ? -2.355  -15.767 27.033  1.000 17.530 0 234  ARG A CB  1 ? 
ATOM   1667 C  CG  . ARG A  1 211 ? -2.436  -14.512 26.172  1.000 18.705 0 234  ARG A CG  1 ? 
ATOM   1668 C  CD  . ARG A  1 211 ? -3.766  -13.806 26.496  1.000 20.213 0 234  ARG A CD  1 ? 
ATOM   1669 N  NE  . ARG A  1 211 ? -3.660  -12.378 26.344  1.000 18.686 0 234  ARG A NE  1 ? 
ATOM   1670 C  CZ  . ARG A  1 211 ? -4.640  -11.509 26.499  1.000 26.196 0 234  ARG A CZ  1 ? 
ATOM   1671 N  NH1 . ARG A  1 211 ? -5.893  -11.905 26.696  1.000 22.776 0 234  ARG A NH1 1 ? 
ATOM   1672 N  NH2 . ARG A  1 211 ? -4.333  -10.228 26.533  1.000 26.732 0 234  ARG A NH2 1 ? 
ATOM   1673 N  N   . THR A  1 212 ? 0.633   -15.660 25.461  1.000 16.987 0 235  THR A N   1 ? 
ATOM   1674 C  CA  . THR A  1 212 ? 1.879   -14.963 25.201  1.000 17.930 0 235  THR A CA  1 ? 
ATOM   1675 C  C   . THR A  1 212 ? 1.768   -14.055 23.976  1.000 18.514 0 235  THR A C   1 ? 
ATOM   1676 O  O   . THR A  1 212 ? 0.756   -14.057 23.297  1.000 18.050 0 235  THR A O   1 ? 
ATOM   1677 C  CB  . THR A  1 212 ? 3.026   -15.954 24.985  1.000 18.169 0 235  THR A CB  1 ? 
ATOM   1678 O  OG1 . THR A  1 212 ? 2.963   -16.552 23.684  1.000 17.874 0 235  THR A OG1 1 ? 
ATOM   1679 C  CG2 . THR A  1 212 ? 3.006   -17.042 26.037  1.000 16.715 0 235  THR A CG2 1 ? 
ATOM   1680 N  N   . SER A  1 213 ? 2.889   -13.399 23.663  1.000 16.719 0 236  SER A N   1 ? 
ATOM   1681 C  CA  . SER A  1 213 ? 3.082   -12.637 22.454  1.000 18.677 0 236  SER A CA  1 ? 
ATOM   1682 C  C   . SER A  1 213 ? 3.724   -13.467 21.352  1.000 16.593 0 236  SER A C   1 ? 
ATOM   1683 O  O   . SER A  1 213 ? 3.954   -12.936 20.273  1.000 18.376 0 236  SER A O   1 ? 
ATOM   1684 C  CB  . SER A  1 213 ? 3.912   -11.428 22.769  1.000 18.039 0 236  SER A CB  1 ? 
ATOM   1685 O  OG  . SER A  1 213 ? 3.358   -10.729 23.864  1.000 20.921 0 236  SER A OG  1 ? 
ATOM   1686 N  N   . GLN A  1 214 ? 4.027   -14.743 21.635  1.000 16.994 0 237  GLN A N   1 ? 
ATOM   1687 C  CA  . GLN A  1 214 ? 4.651   -15.657 20.685  1.000 17.993 0 237  GLN A CA  1 ? 
ATOM   1688 C  C   . GLN A  1 214 ? 3.580   -16.335 19.832  1.000 17.289 0 237  GLN A C   1 ? 
ATOM   1689 O  O   . GLN A  1 214 ? 2.392   -16.074 20.033  1.000 16.963 0 237  GLN A O   1 ? 
ATOM   1690 C  CB  . GLN A  1 214 ? 5.471   -16.699 21.456  1.000 20.421 0 237  GLN A CB  1 ? 
ATOM   1691 C  CG  . GLN A  1 214 ? 6.619   -16.119 22.267  1.000 22.511 0 237  GLN A CG  1 ? 
ATOM   1692 C  CD  . GLN A  1 214 ? 7.622   -15.389 21.418  1.000 25.867 0 237  GLN A CD  1 ? 
ATOM   1693 O  OE1 . GLN A  1 214 ? 8.061   -15.904 20.400  1.000 27.087 0 237  GLN A OE1 1 ? 
ATOM   1694 N  NE2 . GLN A  1 214 ? 7.964   -14.173 21.815  1.000 24.159 0 237  GLN A NE2 1 ? 
ATOM   1695 N  N   . ASP A  1 215 ? 4.007   -17.226 18.925  1.000 17.160 0 238  ASP A N   1 ? 
ATOM   1696 C  CA  . ASP A  1 215 ? 3.125   -17.921 18.013  1.000 18.607 0 238  ASP A CA  1 ? 
ATOM   1697 C  C   . ASP A  1 215 ? 2.302   -18.981 18.739  1.000 18.913 0 238  ASP A C   1 ? 
ATOM   1698 O  O   . ASP A  1 215 ? 1.359   -19.505 18.166  1.000 17.425 0 238  ASP A O   1 ? 
ATOM   1699 C  CB  . ASP A  1 215 ? 3.924   -18.494 16.826  1.000 20.706 0 238  ASP A CB  1 ? 
ATOM   1700 C  CG  . ASP A  1 215 ? 4.471   -17.462 15.850  1.000 21.047 0 238  ASP A CG  1 ? 
ATOM   1701 O  OD1 . ASP A  1 215 ? 4.105   -16.266 15.955  1.000 20.953 0 238  ASP A OD1 1 ? 
ATOM   1702 O  OD2 . ASP A  1 215 ? 5.245   -17.857 14.947  1.000 22.541 0 238  ASP A OD2 1 ? 
ATOM   1703 N  N   . GLN A  1 216 ? 2.703   -19.350 19.957  1.000 18.761 0 239  GLN A N   1 ? 
ATOM   1704 C  CA  . GLN A  1 216 ? 2.038   -20.366 20.740  1.000 19.296 0 239  GLN A CA  1 ? 
ATOM   1705 C  C   . GLN A  1 216 ? 1.989   -19.959 22.211  1.000 18.931 0 239  GLN A C   1 ? 
ATOM   1706 O  O   . GLN A  1 216 ? 2.736   -19.080 22.655  1.000 19.601 0 239  GLN A O   1 ? 
ATOM   1707 C  CB  . GLN A  1 216 ? 2.730   -21.716 20.587  1.000 20.370 0 239  GLN A CB  1 ? 
ATOM   1708 C  CG  . GLN A  1 216 ? 4.183   -21.750 21.040  1.000 20.211 0 239  GLN A CG  1 ? 
ATOM   1709 C  CD  . GLN A  1 216 ? 5.103   -21.228 19.972  1.000 23.776 0 239  GLN A CD  1 ? 
ATOM   1710 O  OE1 . GLN A  1 216 ? 5.166   -21.748 18.861  1.000 29.672 0 239  GLN A OE1 1 ? 
ATOM   1711 N  NE2 . GLN A  1 216 ? 5.758   -20.148 20.325  1.000 26.851 0 239  GLN A NE2 1 ? 
ATOM   1712 N  N   . ALA A  1 217 ? 1.067   -20.592 22.948  1.000 19.896 0 240  ALA A N   1 ? 
ATOM   1713 C  CA  . ALA A  1 217 ? 1.052   -20.535 24.406  1.000 16.898 0 240  ALA A CA  1 ? 
ATOM   1714 C  C   . ALA A  1 217 ? 2.358   -21.113 24.960  1.000 18.234 0 240  ALA A C   1 ? 
ATOM   1715 O  O   . ALA A  1 217 ? 2.975   -21.947 24.300  1.000 17.433 0 240  ALA A O   1 ? 
ATOM   1716 C  CB  . ALA A  1 217 ? -0.095  -21.327 24.948  1.000 16.973 0 240  ALA A CB  1 ? 
ATOM   1717 N  N   . TRP A  1 218 ? 2.801   -20.598 26.106  1.000 18.701 0 241  TRP A N   1 ? 
ATOM   1718 C  CA  . TRP A  1 218 ? 3.954   -21.133 26.811  1.000 17.355 0 241  TRP A CA  1 ? 
ATOM   1719 C  C   . TRP A  1 218 ? 3.495   -21.860 28.068  1.000 21.091 0 241  TRP A C   1 ? 
ATOM   1720 O  O   . TRP A  1 218 ? 2.348   -21.732 28.505  1.000 20.735 0 241  TRP A O   1 ? 
ATOM   1721 C  CB  . TRP A  1 218 ? 4.967   -20.025 27.093  1.000 18.390 0 241  TRP A CB  1 ? 
ATOM   1722 C  CG  . TRP A  1 218 ? 5.835   -19.720 25.907  1.000 19.464 0 241  TRP A CG  1 ? 
ATOM   1723 C  CD1 . TRP A  1 218 ? 5.449   -19.571 24.606  1.000 18.726 0 241  TRP A CD1 1 ? 
ATOM   1724 C  CD2 . TRP A  1 218 ? 7.279   -19.599 25.925  1.000 19.157 0 241  TRP A CD2 1 ? 
ATOM   1725 N  NE1 . TRP A  1 218 ? 6.561   -19.428 23.831  1.000 19.410 0 241  TRP A NE1 1 ? 
ATOM   1726 C  CE2 . TRP A  1 218 ? 7.682   -19.397 24.600  1.000 19.332 0 241  TRP A CE2 1 ? 
ATOM   1727 C  CE3 . TRP A  1 218 ? 8.243   -19.620 26.942  1.000 21.468 0 241  TRP A CE3 1 ? 
ATOM   1728 C  CZ2 . TRP A  1 218 ? 9.021   -19.247 24.237  1.000 24.049 0 241  TRP A CZ2 1 ? 
ATOM   1729 C  CZ3 . TRP A  1 218 ? 9.561   -19.478 26.596  1.000 22.750 0 241  TRP A CZ3 1 ? 
ATOM   1730 C  CH2 . TRP A  1 218 ? 9.939   -19.271 25.260  1.000 24.480 0 241  TRP A CH2 1 ? 
ATOM   1731 N  N   . GLN A  1 219 ? 4.385   -22.689 28.618  1.000 19.327 0 242  GLN A N   1 ? 
ATOM   1732 C  CA  . GLN A  1 219 ? 4.021   -23.558 29.716  1.000 18.287 0 242  GLN A CA  1 ? 
ATOM   1733 C  C   . GLN A  1 219 ? 5.178   -23.672 30.707  1.000 19.657 0 242  GLN A C   1 ? 
ATOM   1734 O  O   . GLN A  1 219 ? 6.343   -23.445 30.354  1.000 19.915 0 242  GLN A O   1 ? 
ATOM   1735 C  CB  . GLN A  1 219 ? 3.600   -24.944 29.217  1.000 18.496 0 242  GLN A CB  1 ? 
ATOM   1736 C  CG  . GLN A  1 219 ? 4.689   -25.701 28.453  1.000 18.855 0 242  GLN A CG  1 ? 
ATOM   1737 C  CD  . GLN A  1 219 ? 4.145   -26.916 27.745  1.000 19.753 0 242  GLN A CD  1 ? 
ATOM   1738 O  OE1 . GLN A  1 219 ? 2.943   -27.052 27.520  1.000 20.729 0 242  GLN A OE1 1 ? 
ATOM   1739 N  NE2 . GLN A  1 219 ? 5.041   -27.812 27.372  1.000 22.980 0 242  GLN A NE2 1 ? 
ATOM   1740 N  N   . ALA A  1 220 ? 4.817   -24.113 31.920  1.000 19.172 0 243  ALA A N   1 ? 
ATOM   1741 C  CA  . ALA A  1 220 ? 5.765   -24.486 32.960  1.000 20.322 0 243  ALA A CA  1 ? 
ATOM   1742 C  C   . ALA A  1 220 ? 5.117   -25.513 33.862  1.000 18.617 0 243  ALA A C   1 ? 
ATOM   1743 O  O   . ALA A  1 220 ? 3.895   -25.707 33.819  1.000 18.803 0 243  ALA A O   1 ? 
ATOM   1744 C  CB  . ALA A  1 220 ? 6.225   -23.293 33.734  1.000 19.741 0 243  ALA A CB  1 ? 
ATOM   1745 N  N   . PHE A  1 221 ? 5.944   -26.141 34.698  1.000 21.054 0 244  PHE A N   1 ? 
ATOM   1746 C  CA  . PHE A  1 221 ? 5.501   -27.260 35.508  1.000 19.355 0 244  PHE A CA  1 ? 
ATOM   1747 C  C   . PHE A  1 221 ? 5.965   -27.108 36.950  1.000 21.548 0 244  PHE A C   1 ? 
ATOM   1748 O  O   . PHE A  1 221 ? 7.021   -26.578 37.223  1.000 21.255 0 244  PHE A O   1 ? 
ATOM   1749 C  CB  . PHE A  1 221 ? 6.031   -28.573 34.947  1.000 20.095 0 244  PHE A CB  1 ? 
ATOM   1750 C  CG  . PHE A  1 221 ? 5.648   -28.808 33.510  1.000 20.251 0 244  PHE A CG  1 ? 
ATOM   1751 C  CD1 . PHE A  1 221 ? 6.394   -28.266 32.475  1.000 23.527 0 244  PHE A CD1 1 ? 
ATOM   1752 C  CD2 . PHE A  1 221 ? 4.442   -29.427 33.213  1.000 19.784 0 244  PHE A CD2 1 ? 
ATOM   1753 C  CE1 . PHE A  1 221 ? 6.000   -28.471 31.155  1.000 22.799 0 244  PHE A CE1 1 ? 
ATOM   1754 C  CE2 . PHE A  1 221 ? 4.042   -29.617 31.902  1.000 22.437 0 244  PHE A CE2 1 ? 
ATOM   1755 C  CZ  . PHE A  1 221 ? 4.809   -29.109 30.881  1.000 22.237 0 244  PHE A CZ  1 ? 
ATOM   1756 N  N   . SER A  1 222 ? 5.133   -27.606 37.876  1.000 21.684 0 245  SER A N   1 ? 
ATOM   1757 C  CA  . SER A  1 222 ? 5.433   -27.555 39.294  1.000 23.003 0 245  SER A CA  1 ? 
ATOM   1758 C  C   . SER A  1 222 ? 5.351   -28.966 39.867  1.000 20.294 0 245  SER A C   1 ? 
ATOM   1759 O  O   . SER A  1 222 ? 4.392   -29.678 39.581  1.000 21.604 0 245  SER A O   1 ? 
ATOM   1760 C  CB  . SER A  1 222 ? 4.514   -26.634 40.036  1.000 22.011 0 245  SER A CB  1 ? 
ATOM   1761 O  OG  . SER A  1 222 ? 4.835   -26.639 41.440  1.000 21.331 0 245  SER A OG  1 ? 
ATOM   1762 N  N   . LYS A  1 223 ? 6.388   -29.321 40.623  1.000 20.447 0 246  LYS A N   1 ? 
ATOM   1763 C  CA  . LYS A  1 223 ? 6.457   -30.568 41.378  1.000 23.197 0 246  LYS A CA  1 ? 
ATOM   1764 C  C   . LYS A  1 223 ? 6.133   -30.385 42.859  1.000 24.856 0 246  LYS A C   1 ? 
ATOM   1765 O  O   . LYS A  1 223 ? 6.127   -31.352 43.636  1.000 25.903 0 246  LYS A O   1 ? 
ATOM   1766 C  CB  . LYS A  1 223 ? 7.863   -31.157 41.253  1.000 26.954 0 246  LYS A CB  1 ? 
ATOM   1767 C  CG  . LYS A  1 223 ? 8.362   -31.383 39.833  1.000 30.184 0 246  LYS A CG  1 ? 
ATOM   1768 C  CD  . LYS A  1 223 ? 7.556   -32.374 39.090  1.000 38.110 0 246  LYS A CD  1 ? 
ATOM   1769 C  CE  . LYS A  1 223 ? 8.200   -32.863 37.805  1.000 43.608 0 246  LYS A CE  1 ? 
ATOM   1770 N  NZ  . LYS A  1 223 ? 7.266   -33.756 37.061  1.000 39.222 0 246  LYS A NZ  1 ? 
ATOM   1771 N  N   . ASP A  1 224 ? 5.802   -29.164 43.278  1.000 23.228 0 247  ASP A N   1 ? 
ATOM   1772 C  CA  . ASP A  1 224 ? 5.462   -28.922 44.667  1.000 21.328 0 247  ASP A CA  1 ? 
ATOM   1773 C  C   . ASP A  1 224 ? 4.096   -28.240 44.817  1.000 23.664 0 247  ASP A C   1 ? 
ATOM   1774 O  O   . ASP A  1 224 ? 3.923   -27.390 45.682  1.000 23.047 0 247  ASP A O   1 ? 
ATOM   1775 C  CB  . ASP A  1 224 ? 6.616   -28.190 45.336  1.000 23.017 0 247  ASP A CB  1 ? 
ATOM   1776 C  CG  . ASP A  1 224 ? 6.976   -26.862 44.698  1.000 26.581 0 247  ASP A CG  1 ? 
ATOM   1777 O  OD1 . ASP A  1 224 ? 6.147   -26.335 43.894  1.000 24.686 0 247  ASP A OD1 1 ? 
ATOM   1778 O  OD2 . ASP A  1 224 ? 8.051   -26.334 45.051  1.000 26.755 0 247  ASP A OD2 1 ? 
ATOM   1779 N  N   . TYR A  1 225 ? 3.133   -28.610 43.963  1.000 21.963 0 248  TYR A N   1 ? 
ATOM   1780 C  CA  . TYR A  1 225 ? 1.771   -28.080 43.994  1.000 21.873 0 248  TYR A CA  1 ? 
ATOM   1781 C  C   . TYR A  1 225 ? 1.760   -26.549 43.972  1.000 21.916 0 248  TYR A C   1 ? 
ATOM   1782 O  O   . TYR A  1 225 ? 0.945   -25.936 44.658  1.000 22.511 0 248  TYR A O   1 ? 
ATOM   1783 C  CB  . TYR A  1 225 ? 1.027   -28.614 45.214  1.000 22.359 0 248  TYR A CB  1 ? 
ATOM   1784 C  CG  . TYR A  1 225 ? 0.940   -30.137 45.108  1.000 25.231 0 248  TYR A CG  1 ? 
ATOM   1785 C  CD1 . TYR A  1 225 ? 0.051   -30.736 44.220  1.000 26.320 0 248  TYR A CD1 1 ? 
ATOM   1786 C  CD2 . TYR A  1 225 ? 1.791   -30.958 45.849  1.000 27.541 0 248  TYR A CD2 1 ? 
ATOM   1787 C  CE1 . TYR A  1 225 ? 0.000   -32.111 44.079  1.000 29.052 0 248  TYR A CE1 1 ? 
ATOM   1788 C  CE2 . TYR A  1 225 ? 1.751   -32.336 45.711  1.000 31.574 0 248  TYR A CE2 1 ? 
ATOM   1789 C  CZ  . TYR A  1 225 ? 0.838   -32.907 44.837  1.000 31.382 0 248  TYR A CZ  1 ? 
ATOM   1790 O  OH  . TYR A  1 225 ? 0.787   -34.251 44.657  1.000 35.950 0 248  TYR A OH  1 ? 
ATOM   1791 N  N   . GLY A  1 226 ? 2.656   -25.969 43.167  1.000 22.844 0 249  GLY A N   1 ? 
ATOM   1792 C  CA  . GLY A  1 226 ? 2.554   -24.588 42.719  1.000 22.893 0 249  GLY A CA  1 ? 
ATOM   1793 C  C   . GLY A  1 226 ? 3.425   -23.600 43.483  1.000 21.528 0 249  GLY A C   1 ? 
ATOM   1794 O  O   . GLY A  1 226 ? 3.404   -22.401 43.185  1.000 20.763 0 249  GLY A O   1 ? 
ATOM   1795 N  N   . GLU A  1 227 ? 4.251   -24.083 44.425  1.000 20.456 0 250  GLU A N   1 ? 
ATOM   1796 C  CA  . GLU A  1 227 ? 5.183   -23.207 45.118  1.000 24.288 0 250  GLU A CA  1 ? 
ATOM   1797 C  C   . GLU A  1 227 ? 6.276   -22.719 44.182  1.000 21.602 0 250  GLU A C   1 ? 
ATOM   1798 O  O   . GLU A  1 227 ? 6.672   -21.551 44.216  1.000 22.012 0 250  GLU A O   1 ? 
ATOM   1799 C  CB  . GLU A  1 227 ? 5.988   -23.910 46.215  1.000 29.314 0 250  GLU A CB  1 ? 
ATOM   1800 C  CG  . GLU A  1 227 ? 5.414   -23.889 47.573  1.000 39.131 0 250  GLU A CG  1 ? 
ATOM   1801 C  CD  . GLU A  1 227 ? 4.858   -22.578 48.080  1.000 34.036 0 250  GLU A CD  1 ? 
ATOM   1802 O  OE1 . GLU A  1 227 ? 3.751   -22.680 48.481  1.000 35.582 0 250  GLU A OE1 1 ? 
ATOM   1803 O  OE2 . GLU A  1 227 ? 5.524   -21.513 48.038  1.000 37.647 0 250  GLU A OE2 1 ? 
ATOM   1804 N  N   . THR A  1 228 ? 6.819   -23.642 43.376  1.000 22.514 0 251  THR A N   1 ? 
ATOM   1805 C  CA  . THR A  1 228 ? 7.891   -23.290 42.468  1.000 22.224 0 251  THR A CA  1 ? 
ATOM   1806 C  C   . THR A  1 228 ? 7.654   -23.976 41.125  1.000 21.381 0 251  THR A C   1 ? 
ATOM   1807 O  O   . THR A  1 228 ? 7.051   -25.052 41.062  1.000 22.930 0 251  THR A O   1 ? 
ATOM   1808 C  CB  . THR A  1 228 ? 9.271   -23.711 43.006  1.000 24.915 0 251  THR A CB  1 ? 
ATOM   1809 O  OG1 . THR A  1 228 ? 9.293   -25.144 43.037  1.000 23.038 0 251  THR A OG1 1 ? 
ATOM   1810 C  CG2 . THR A  1 228 ? 9.561   -23.150 44.385  1.000 29.682 0 251  THR A CG2 1 ? 
ATOM   1811 N  N   . TRP A  1 229 ? 8.197   -23.351 40.081  1.000 20.986 0 252  TRP A N   1 ? 
ATOM   1812 C  CA  . TRP A  1 229 ? 7.893   -23.732 38.707  1.000 21.007 0 252  TRP A CA  1 ? 
ATOM   1813 C  C   . TRP A  1 229 ? 9.165   -23.809 37.893  1.000 20.116 0 252  TRP A C   1 ? 
ATOM   1814 O  O   . TRP A  1 229 ? 10.106  -23.053 38.106  1.000 21.674 0 252  TRP A O   1 ? 
ATOM   1815 C  CB  . TRP A  1 229 ? 6.953   -22.710 38.043  1.000 19.876 0 252  TRP A CB  1 ? 
ATOM   1816 C  CG  . TRP A  1 229 ? 5.632   -22.685 38.744  1.000 19.305 0 252  TRP A CG  1 ? 
ATOM   1817 C  CD1 . TRP A  1 229 ? 5.345   -22.036 39.903  1.000 17.778 0 252  TRP A CD1 1 ? 
ATOM   1818 C  CD2 . TRP A  1 229 ? 4.450   -23.396 38.370  1.000 18.345 0 252  TRP A CD2 1 ? 
ATOM   1819 N  NE1 . TRP A  1 229 ? 4.062   -22.305 40.270  1.000 18.432 0 252  TRP A NE1 1 ? 
ATOM   1820 C  CE2 . TRP A  1 229 ? 3.484   -23.119 39.344  1.000 17.609 0 252  TRP A CE2 1 ? 
ATOM   1821 C  CE3 . TRP A  1 229 ? 4.110   -24.211 37.290  1.000 17.676 0 252  TRP A CE3 1 ? 
ATOM   1822 C  CZ2 . TRP A  1 229 ? 2.193   -23.626 39.292  1.000 17.764 0 252  TRP A CZ2 1 ? 
ATOM   1823 C  CZ3 . TRP A  1 229 ? 2.832   -24.713 37.241  1.000 19.066 0 252  TRP A CZ3 1 ? 
ATOM   1824 C  CH2 . TRP A  1 229 ? 1.908   -24.471 38.248  1.000 17.976 0 252  TRP A CH2 1 ? 
ATOM   1825 N  N   . SER A  1 230 ? 9.138   -24.699 36.916  1.000 21.844 0 253  SER A N   1 ? 
ATOM   1826 C  CA  . SER A  1 230 ? 10.256  -24.910 36.010  1.000 23.703 0 253  SER A CA  1 ? 
ATOM   1827 C  C   . SER A  1 230 ? 10.479  -23.700 35.103  1.000 23.906 0 253  SER A C   1 ? 
ATOM   1828 O  O   . SER A  1 230 ? 9.624   -22.829 34.968  1.000 24.191 0 253  SER A O   1 ? 
ATOM   1829 C  CB  . SER A  1 230 ? 10.014  -26.150 35.171  1.000 23.347 0 253  SER A CB  1 ? 
ATOM   1830 O  OG  . SER A  1 230 ? 8.850   -26.015 34.330  1.000 24.121 0 253  SER A OG  1 ? 
ATOM   1831 N  N   . LYS A  1 231 ? 11.611  -23.734 34.398  1.000 22.429 0 254  LYS A N   1 ? 
ATOM   1832 C  CA  . LYS A  1 231 ? 11.899  -22.827 33.298  1.000 25.419 0 254  LYS A CA  1 ? 
ATOM   1833 C  C   . LYS A  1 231 ? 10.784  -22.933 32.245  1.000 23.614 0 254  LYS A C   1 ? 
ATOM   1834 O  O   . LYS A  1 231 ? 10.390  -24.024 31.829  1.000 23.400 0 254  LYS A O   1 ? 
ATOM   1835 C  CB  . LYS A  1 231 ? 13.239  -23.272 32.717  1.000 29.652 0 254  LYS A CB  1 ? 
ATOM   1836 C  CG  . LYS A  1 231 ? 13.810  -22.485 31.555  1.000 41.220 0 254  LYS A CG  1 ? 
ATOM   1837 C  CD  . LYS A  1 231 ? 15.116  -23.151 31.103  1.000 50.986 0 254  LYS A CD  1 ? 
ATOM   1838 C  CE  . LYS A  1 231 ? 15.363  -23.042 29.614  1.000 60.193 0 254  LYS A CE  1 ? 
ATOM   1839 N  NZ  . LYS A  1 231 ? 15.592  -21.634 29.216  1.000 61.415 0 254  LYS A NZ  1 ? 
ATOM   1840 N  N   . PRO A  1 232 ? 10.212  -21.805 31.796  1.000 22.591 0 255  PRO A N   1 ? 
ATOM   1841 C  CA  . PRO A  1 232 ? 9.116   -21.824 30.824  1.000 24.719 0 255  PRO A CA  1 ? 
ATOM   1842 C  C   . PRO A  1 232 ? 9.601   -22.190 29.418  1.000 22.998 0 255  PRO A C   1 ? 
ATOM   1843 O  O   . PRO A  1 232 ? 10.758  -21.958 29.030  1.000 22.046 0 255  PRO A O   1 ? 
ATOM   1844 C  CB  . PRO A  1 232 ? 8.542   -20.394 30.959  1.000 23.387 0 255  PRO A CB  1 ? 
ATOM   1845 C  CG  . PRO A  1 232 ? 9.717   -19.584 31.268  1.000 26.313 0 255  PRO A CG  1 ? 
ATOM   1846 C  CD  . PRO A  1 232 ? 10.601  -20.439 32.160  1.000 24.353 0 255  PRO A CD  1 ? 
ATOM   1847 N  N   . GLU A  1 233 ? 8.695   -22.812 28.652  1.000 21.152 0 256  GLU A N   1 ? 
ATOM   1848 C  CA  . GLU A  1 233 ? 9.000   -23.287 27.314  1.000 20.558 0 256  GLU A CA  1 ? 
ATOM   1849 C  C   . GLU A  1 233 ? 7.758   -23.133 26.430  1.000 21.089 0 256  GLU A C   1 ? 
ATOM   1850 O  O   . GLU A  1 233 ? 6.636   -23.101 26.931  1.000 20.488 0 256  GLU A O   1 ? 
ATOM   1851 C  CB  . GLU A  1 233 ? 9.403   -24.760 27.351  1.000 20.911 0 256  GLU A CB  1 ? 
ATOM   1852 C  CG  . GLU A  1 233 ? 8.308   -25.692 27.859  1.000 23.115 0 256  GLU A CG  1 ? 
ATOM   1853 C  CD  . GLU A  1 233 ? 8.726   -27.161 27.975  1.000 27.846 0 256  GLU A CD  1 ? 
ATOM   1854 O  OE1 . GLU A  1 233 ? 7.867   -28.040 28.081  1.000 24.171 0 256  GLU A OE1 1 ? 
ATOM   1855 O  OE2 . GLU A  1 233 ? 9.928   -27.406 27.964  1.000 29.922 0 256  GLU A OE2 1 ? 
ATOM   1856 N  N   . PRO A  1 234 ? 7.908   -23.124 25.087  1.000 22.748 0 257  PRO A N   1 ? 
ATOM   1857 C  CA  . PRO A  1 234 ? 6.752   -23.130 24.188  1.000 21.059 0 257  PRO A CA  1 ? 
ATOM   1858 C  C   . PRO A  1 234 ? 5.929   -24.381 24.368  1.000 21.680 0 257  PRO A C   1 ? 
ATOM   1859 O  O   . PRO A  1 234 ? 6.481   -25.470 24.548  1.000 21.855 0 257  PRO A O   1 ? 
ATOM   1860 C  CB  . PRO A  1 234 ? 7.315   -23.103 22.752  1.000 22.116 0 257  PRO A CB  1 ? 
ATOM   1861 C  CG  . PRO A  1 234 ? 8.842   -22.919 22.899  1.000 23.664 0 257  PRO A CG  1 ? 
ATOM   1862 C  CD  . PRO A  1 234 ? 9.186   -22.949 24.376  1.000 23.128 0 257  PRO A CD  1 ? 
ATOM   1863 N  N   . SER A  1 235 ? 4.602   -24.221 24.370  1.000 20.079 0 258  SER A N   1 ? 
ATOM   1864 C  CA  . SER A  1 235 ? 3.694   -25.345 24.311  1.000 19.163 0 258  SER A CA  1 ? 
ATOM   1865 C  C   . SER A  1 235 ? 3.400   -25.781 22.870  1.000 16.653 0 258  SER A C   1 ? 
ATOM   1866 O  O   . SER A  1 235 ? 3.750   -25.108 21.905  1.000 19.677 0 258  SER A O   1 ? 
ATOM   1867 C  CB  . SER A  1 235 ? 2.396   -25.017 25.000  1.000 19.740 0 258  SER A CB  1 ? 
ATOM   1868 O  OG  . SER A  1 235 ? 1.560   -24.280 24.116  1.000 20.333 0 258  SER A OG  1 ? 
ATOM   1869 N  N   . ARG A  1 236 ? 2.636   -26.863 22.748  1.000 18.364 0 259  ARG A N   1 ? 
ATOM   1870 C  CA  . ARG A  1 236 ? 2.216   -27.369 21.444  1.000 21.136 0 259  ARG A CA  1 ? 
ATOM   1871 C  C   . ARG A  1 236 ? 0.975   -26.621 20.936  1.000 20.011 0 259  ARG A C   1 ? 
ATOM   1872 O  O   . ARG A  1 236 ? 0.585   -26.848 19.791  1.000 20.820 0 259  ARG A O   1 ? 
ATOM   1873 C  CB  . ARG A  1 236 ? 1.878   -28.879 21.457  1.000 19.451 0 259  ARG A CB  1 ? 
ATOM   1874 C  CG  . ARG A  1 236 ? 0.584   -29.214 22.163  1.000 20.459 0 259  ARG A CG  1 ? 
ATOM   1875 C  CD  . ARG A  1 236 ? 0.180   -30.674 22.097  1.000 25.382 0 259  ARG A CD  1 ? 
ATOM   1876 N  NE  . ARG A  1 236 ? 1.273   -31.489 22.594  1.000 26.382 0 259  ARG A NE  1 ? 
ATOM   1877 C  CZ  . ARG A  1 236 ? 1.953   -32.385 21.899  1.000 32.159 0 259  ARG A CZ  1 ? 
ATOM   1878 N  NH1 . ARG A  1 236 ? 1.829   -32.500 20.599  1.000 32.828 0 259  ARG A NH1 1 ? 
ATOM   1879 N  NH2 . ARG A  1 236 ? 2.779   -33.189 22.526  1.000 31.931 0 259  ARG A NH2 1 ? 
ATOM   1880 N  N   . PHE A  1 237 ? 0.365   -25.753 21.769  1.000 19.770 0 260  PHE A N   1 ? 
ATOM   1881 C  CA  . PHE A  1 237 ? -0.897  -25.133 21.402  1.000 18.419 0 260  PHE A CA  1 ? 
ATOM   1882 C  C   . PHE A  1 237 ? -0.661  -23.743 20.806  1.000 18.231 0 260  PHE A C   1 ? 
ATOM   1883 O  O   . PHE A  1 237 ? -0.409  -22.760 21.522  1.000 20.421 0 260  PHE A O   1 ? 
ATOM   1884 C  CB  . PHE A  1 237 ? -1.845  -25.134 22.590  1.000 18.953 0 260  PHE A CB  1 ? 
ATOM   1885 C  CG  . PHE A  1 237 ? -2.185  -26.520 23.069  1.000 18.041 0 260  PHE A CG  1 ? 
ATOM   1886 C  CD1 . PHE A  1 237 ? -3.010  -27.332 22.317  1.000 18.997 0 260  PHE A CD1 1 ? 
ATOM   1887 C  CD2 . PHE A  1 237 ? -1.597  -27.051 24.205  1.000 19.807 0 260  PHE A CD2 1 ? 
ATOM   1888 C  CE1 . PHE A  1 237 ? -3.324  -28.615 22.742  1.000 20.518 0 260  PHE A CE1 1 ? 
ATOM   1889 C  CE2 . PHE A  1 237 ? -1.894  -28.344 24.617  1.000 20.047 0 260  PHE A CE2 1 ? 
ATOM   1890 C  CZ  . PHE A  1 237 ? -2.757  -29.120 23.888  1.000 20.755 0 260  PHE A CZ  1 ? 
ATOM   1891 N  N   . PHE A  1 238 ? -0.825  -23.661 19.486  1.000 17.473 0 261  PHE A N   1 ? 
ATOM   1892 C  CA  . PHE A  1 238 ? -0.613  -22.408 18.772  1.000 18.072 0 261  PHE A CA  1 ? 
ATOM   1893 C  C   . PHE A  1 238 ? -1.643  -21.374 19.171  1.000 17.427 0 261  PHE A C   1 ? 
ATOM   1894 O  O   . PHE A  1 238 ? -2.771  -21.701 19.507  1.000 19.404 0 261  PHE A O   1 ? 
ATOM   1895 C  CB  . PHE A  1 238 ? -0.622  -22.601 17.259  1.000 18.014 0 261  PHE A CB  1 ? 
ATOM   1896 C  CG  . PHE A  1 238 ? 0.584   -23.334 16.752  1.000 18.054 0 261  PHE A CG  1 ? 
ATOM   1897 C  CD1 . PHE A  1 238 ? 1.800   -22.688 16.615  1.000 18.160 0 261  PHE A CD1 1 ? 
ATOM   1898 C  CD2 . PHE A  1 238 ? 0.532   -24.707 16.528  1.000 19.923 0 261  PHE A CD2 1 ? 
ATOM   1899 C  CE1 . PHE A  1 238 ? 2.936   -23.361 16.184  1.000 20.274 0 261  PHE A CE1 1 ? 
ATOM   1900 C  CE2 . PHE A  1 238 ? 1.671   -25.373 16.087  1.000 20.890 0 261  PHE A CE2 1 ? 
ATOM   1901 C  CZ  . PHE A  1 238 ? 2.867   -24.708 15.936  1.000 19.122 0 261  PHE A CZ  1 ? 
ATOM   1902 N  N   . GLY A  1 239 ? -1.251  -20.115 19.053  1.000 17.422 0 262  GLY A N   1 ? 
ATOM   1903 C  CA  . GLY A  1 239 ? -2.133  -19.013 19.373  1.000 19.500 0 262  GLY A CA  1 ? 
ATOM   1904 C  C   . GLY A  1 239 ? -1.358  -17.892 20.076  1.000 19.254 0 262  GLY A C   1 ? 
ATOM   1905 O  O   . GLY A  1 239 ? -0.335  -18.137 20.728  1.000 19.424 0 262  GLY A O   1 ? 
ATOM   1906 N  N   . THR A  1 240 ? -1.854  -16.668 19.890  1.000 18.288 0 263  THR A N   1 ? 
ATOM   1907 C  CA  . THR A  1 240 ? -1.167  -15.444 20.288  1.000 19.243 0 263  THR A CA  1 ? 
ATOM   1908 C  C   . THR A  1 240 ? -2.213  -14.522 20.915  1.000 18.640 0 263  THR A C   1 ? 
ATOM   1909 O  O   . THR A  1 240 ? -3.196  -14.184 20.263  1.000 16.337 0 263  THR A O   1 ? 
ATOM   1910 C  CB  . THR A  1 240 ? -0.561  -14.767 19.044  1.000 20.633 0 263  THR A CB  1 ? 
ATOM   1911 O  OG1 . THR A  1 240 ? 0.316   -15.705 18.422  1.000 21.642 0 263  THR A OG1 1 ? 
ATOM   1912 C  CG2 . THR A  1 240 ? 0.164   -13.470 19.310  1.000 20.870 0 263  THR A CG2 1 ? 
ATOM   1913 N  N   . LEU A  1 241 ? -1.971  -14.083 22.158  1.000 16.570 0 264  LEU A N   1 ? 
ATOM   1914 C  CA  . LEU A  1 241 ? -2.788  -13.090 22.832  1.000 18.110 0 264  LEU A CA  1 ? 
ATOM   1915 C  C   . LEU A  1 241 ? -4.235  -13.583 22.960  1.000 20.413 0 264  LEU A C   1 ? 
ATOM   1916 O  O   . LEU A  1 241 ? -5.151  -12.762 23.069  1.000 18.603 0 264  LEU A O   1 ? 
ATOM   1917 C  CB  . LEU A  1 241 ? -2.661  -11.745 22.084  1.000 18.951 0 264  LEU A CB  1 ? 
ATOM   1918 C  CG  . LEU A  1 241 ? -1.266  -11.113 22.031  1.000 21.163 0 264  LEU A CG  1 ? 
ATOM   1919 C  CD1 . LEU A  1 241 ? -1.264  -9.863  21.129  1.000 22.407 0 264  LEU A CD1 1 ? 
ATOM   1920 C  CD2 . LEU A  1 241 ? -0.785  -10.719 23.412  1.000 23.460 0 264  LEU A CD2 1 ? 
ATOM   1921 N  N   . THR A  1 242 ? -4.414  -14.929 22.994  1.000 18.253 0 265  THR A N   1 ? 
ATOM   1922 C  CA  . THR A  1 242 ? -5.690  -15.610 23.202  1.000 18.897 0 265  THR A CA  1 ? 
ATOM   1923 C  C   . THR A  1 242 ? -5.516  -16.598 24.365  1.000 18.673 0 265  THR A C   1 ? 
ATOM   1924 O  O   . THR A  1 242 ? -4.401  -16.799 24.840  1.000 18.981 0 265  THR A O   1 ? 
ATOM   1925 C  CB  . THR A  1 242 ? -6.206  -16.296 21.926  1.000 20.749 0 265  THR A CB  1 ? 
ATOM   1926 O  OG1 . THR A  1 242 ? -5.223  -17.173 21.390  1.000 20.598 0 265  THR A OG1 1 ? 
ATOM   1927 C  CG2 . THR A  1 242 ? -6.577  -15.298 20.847  1.000 23.513 0 265  THR A CG2 1 ? 
ATOM   1928 N  N   . MET A  1 243 ? -6.617  -17.196 24.823  1.000 18.630 0 266  MET A N   1 ? 
ATOM   1929 C  CA  . MET A  1 243 ? -6.640  -17.845 26.110  1.000 17.701 0 266  MET A CA  1 ? 
ATOM   1930 C  C   . MET A  1 243 ? -6.816  -19.363 25.983  1.000 18.193 0 266  MET A C   1 ? 
ATOM   1931 O  O   . MET A  1 243 ? -7.461  -19.865 25.062  1.000 17.516 0 266  MET A O   1 ? 
ATOM   1932 C  CB  . MET A  1 243 ? -7.757  -17.226 26.953  1.000 20.996 0 266  MET A CB  1 ? 
ATOM   1933 C  CG  . MET A  1 243 ? -7.448  -15.770 27.356  1.000 21.966 0 266  MET A CG  1 ? 
ATOM   1934 S  SD  . MET A  1 243 ? -7.638  -14.527 26.026  1.000 25.962 0 266  MET A SD  1 ? 
ATOM   1935 C  CE  . MET A  1 243 ? -9.280  -13.898 26.396  1.000 29.309 0 266  MET A CE  1 ? 
ATOM   1936 N  N   . ASN A  1 244 ? -6.219  -20.064 26.954  1.000 17.124 0 267  ASN A N   1 ? 
ATOM   1937 C  CA  . ASN A  1 244 ? -6.201  -21.518 27.041  1.000 17.402 0 267  ASN A CA  1 ? 
ATOM   1938 C  C   . ASN A  1 244 ? -7.053  -21.952 28.226  1.000 17.548 0 267  ASN A C   1 ? 
ATOM   1939 O  O   . ASN A  1 244 ? -7.036  -21.281 29.261  1.000 16.003 0 267  ASN A O   1 ? 
ATOM   1940 C  CB  . ASN A  1 244 ? -4.780  -22.008 27.302  1.000 19.467 0 267  ASN A CB  1 ? 
ATOM   1941 C  CG  . ASN A  1 244 ? -3.829  -21.561 26.215  1.000 19.354 0 267  ASN A CG  1 ? 
ATOM   1942 O  OD1 . ASN A  1 244 ? -3.213  -20.497 26.300  1.000 19.135 0 267  ASN A OD1 1 ? 
ATOM   1943 N  ND2 . ASN A  1 244 ? -3.767  -22.350 25.162  1.000 18.910 0 267  ASN A ND2 1 ? 
ATOM   1944 N  N   . THR A  1 245 ? -7.750  -23.084 28.101  1.000 16.574 0 268  THR A N   1 ? 
ATOM   1945 C  CA  . THR A  1 245 ? -8.374  -23.711 29.252  1.000 16.981 0 268  THR A CA  1 ? 
ATOM   1946 C  C   . THR A  1 245 ? -8.113  -25.213 29.194  1.000 18.582 0 268  THR A C   1 ? 
ATOM   1947 O  O   . THR A  1 245 ? -8.419  -25.855 28.173  1.000 18.046 0 268  THR A O   1 ? 
ATOM   1948 C  CB  . THR A  1 245 ? -9.884  -23.418 29.264  1.000 18.212 0 268  THR A CB  1 ? 
ATOM   1949 O  OG1 . THR A  1 245 ? -10.095 -21.993 29.286  1.000 20.283 0 268  THR A OG1 1 ? 
ATOM   1950 C  CG2 . THR A  1 245 ? -10.587 -24.032 30.442  1.000 18.047 0 268  THR A CG2 1 ? 
ATOM   1951 N  N   . LEU A  1 246 ? -7.661  -25.759 30.322  1.000 18.823 0 269  LEU A N   1 ? 
ATOM   1952 C  CA  . LEU A  1 246 ? -7.455  -27.194 30.468  1.000 19.492 0 269  LEU A CA  1 ? 
ATOM   1953 C  C   . LEU A  1 246 ? -8.467  -27.764 31.431  1.000 20.788 0 269  LEU A C   1 ? 
ATOM   1954 O  O   . LEU A  1 246 ? -8.848  -27.113 32.405  1.000 19.825 0 269  LEU A O   1 ? 
ATOM   1955 C  CB  . LEU A  1 246 ? -6.047  -27.434 31.011  1.000 19.225 0 269  LEU A CB  1 ? 
ATOM   1956 C  CG  . LEU A  1 246 ? -4.948  -27.114 30.024  1.000 19.034 0 269  LEU A CG  1 ? 
ATOM   1957 C  CD1 . LEU A  1 246 ? -3.598  -27.079 30.701  1.000 19.035 0 269  LEU A CD1 1 ? 
ATOM   1958 C  CD2 . LEU A  1 246 ? -4.930  -28.130 28.890  1.000 20.818 0 269  LEU A CD2 1 ? 
ATOM   1959 N  N   . GLY A  1 247 ? -8.906  -28.980 31.146  1.000 20.131 0 270  GLY A N   1 ? 
ATOM   1960 C  CA  . GLY A  1 247 ? -9.791  -29.693 32.035  1.000 20.265 0 270  GLY A CA  1 ? 
ATOM   1961 C  C   . GLY A  1 247 ? -9.647  -31.205 31.891  1.000 20.327 0 270  GLY A C   1 ? 
ATOM   1962 O  O   . GLY A  1 247 ? -8.887  -31.714 31.071  1.000 20.379 0 270  GLY A O   1 ? 
ATOM   1963 N  N   . ARG A  1 248 ? -10.355 -31.912 32.755  1.000 23.919 0 271  ARG A N   1 ? 
ATOM   1964 C  CA  . ARG A  1 248 ? -10.228 -33.366 32.818  1.000 24.927 0 271  ARG A CA  1 ? 
ATOM   1965 C  C   . ARG A  1 248 ? -11.624 -33.966 32.935  1.000 23.721 0 271  ARG A C   1 ? 
ATOM   1966 O  O   . ARG A  1 248 ? -12.423 -33.519 33.758  1.000 23.524 0 271  ARG A O   1 ? 
ATOM   1967 C  CB  . ARG A  1 248 ? -9.376  -33.827 34.006  1.000 27.323 0 271  ARG A CB  1 ? 
ATOM   1968 C  CG  . ARG A  1 248 ? -9.030  -35.318 33.938  1.000 26.721 0 271  ARG A CG  1 ? 
ATOM   1969 C  CD  . ARG A  1 248 ? -8.180  -35.746 35.122  1.000 27.456 0 271  ARG A CD  1 ? 
ATOM   1970 N  NE  . ARG A  1 248 ? -6.851  -35.135 35.097  1.000 24.393 0 271  ARG A NE  1 ? 
ATOM   1971 C  CZ  . ARG A  1 248 ? -5.788  -35.619 34.472  1.000 21.751 0 271  ARG A CZ  1 ? 
ATOM   1972 N  NH1 . ARG A  1 248 ? -5.906  -36.666 33.674  1.000 21.915 0 271  ARG A NH1 1 ? 
ATOM   1973 N  NH2 . ARG A  1 248 ? -4.609  -35.052 34.635  1.000 22.339 0 271  ARG A NH2 1 ? 
ATOM   1974 N  N   . LEU A  1 249 ? -11.890 -34.997 32.117  1.000 25.254 0 272  LEU A N   1 ? 
ATOM   1975 C  CA  . LEU A  1 249 ? -13.158 -35.706 32.197  1.000 25.350 0 272  LEU A CA  1 ? 
ATOM   1976 C  C   . LEU A  1 249 ? -13.106 -36.768 33.298  1.000 24.418 0 272  LEU A C   1 ? 
ATOM   1977 O  O   . LEU A  1 249 ? -12.027 -37.174 33.701  1.000 25.014 0 272  LEU A O   1 ? 
ATOM   1978 C  CB  . LEU A  1 249 ? -13.425 -36.379 30.852  1.000 25.646 0 272  LEU A CB  1 ? 
ATOM   1979 C  CG  . LEU A  1 249 ? -13.473 -35.459 29.641  1.000 25.834 0 272  LEU A CG  1 ? 
ATOM   1980 C  CD1 . LEU A  1 249 ? -13.900 -36.271 28.434  1.000 28.160 0 272  LEU A CD1 1 ? 
ATOM   1981 C  CD2 . LEU A  1 249 ? -14.411 -34.290 29.877  1.000 26.046 0 272  LEU A CD2 1 ? 
ATOM   1982 N  N   . ASP A  1 250 ? -14.288 -37.300 33.639  1.000 26.541 0 273  ASP A N   1 ? 
ATOM   1983 C  CA  . ASP A  1 250 ? -14.451 -38.270 34.716  1.000 28.591 0 273  ASP A CA  1 ? 
ATOM   1984 C  C   . ASP A  1 250 ? -13.569 -39.482 34.509  1.000 29.590 0 273  ASP A C   1 ? 
ATOM   1985 O  O   . ASP A  1 250 ? -13.005 -39.949 35.487  1.000 35.802 0 273  ASP A O   1 ? 
ATOM   1986 C  CB  . ASP A  1 250 ? -15.895 -38.712 34.878  1.000 31.744 0 273  ASP A CB  1 ? 
ATOM   1987 C  CG  . ASP A  1 250 ? -16.772 -37.662 35.532  1.000 43.776 0 273  ASP A CG  1 ? 
ATOM   1988 O  OD1 . ASP A  1 250 ? -16.275 -36.947 36.432  1.000 55.083 0 273  ASP A OD1 1 ? 
ATOM   1989 O  OD2 . ASP A  1 250 ? -17.959 -37.587 35.163  1.000 60.231 0 273  ASP A OD2 1 ? 
ATOM   1990 N  N   . ASP A  1 251 ? -13.392 -39.930 33.266  1.000 27.120 0 274  ASP A N   1 ? 
ATOM   1991 C  CA  . ASP A  1 251 ? -12.568 -41.088 32.951  1.000 30.152 0 274  ASP A CA  1 ? 
ATOM   1992 C  C   . ASP A  1 251 ? -11.073 -40.768 32.891  1.000 29.206 0 274  ASP A C   1 ? 
ATOM   1993 O  O   . ASP A  1 251 ? -10.279 -41.630 32.510  1.000 28.606 0 274  ASP A O   1 ? 
ATOM   1994 C  CB  . ASP A  1 251 ? -12.990 -41.759 31.634  1.000 32.706 0 274  ASP A CB  1 ? 
ATOM   1995 C  CG  . ASP A  1 251 ? -12.595 -41.064 30.329  1.000 37.409 0 274  ASP A CG  1 ? 
ATOM   1996 O  OD1 . ASP A  1 251 ? -12.030 -39.974 30.374  1.000 37.136 0 274  ASP A OD1 1 ? 
ATOM   1997 O  OD2 . ASP A  1 251 ? -12.863 -41.636 29.248  1.000 36.714 0 274  ASP A OD2 1 ? 
ATOM   1998 N  N   . GLY A  1 252 ? -10.680 -39.515 33.133  1.000 27.858 0 275  GLY A N   1 ? 
ATOM   1999 C  CA  . GLY A  1 252 ? -9.250  -39.197 33.143  1.000 25.163 0 275  GLY A CA  1 ? 
ATOM   2000 C  C   . GLY A  1 252 ? -8.740  -38.465 31.896  1.000 23.861 0 275  GLY A C   1 ? 
ATOM   2001 O  O   . GLY A  1 252 ? -7.620  -37.974 31.898  1.000 25.316 0 275  GLY A O   1 ? 
ATOM   2002 N  N   . THR A  1 253 ? -9.529  -38.433 30.808  1.000 23.699 0 276  THR A N   1 ? 
ATOM   2003 C  CA  . THR A  1 253 ? -9.099  -37.815 29.568  1.000 22.711 0 276  THR A CA  1 ? 
ATOM   2004 C  C   . THR A  1 253 ? -8.935  -36.312 29.786  1.000 22.957 0 276  THR A C   1 ? 
ATOM   2005 O  O   . THR A  1 253 ? -9.757  -35.696 30.445  1.000 23.310 0 276  THR A O   1 ? 
ATOM   2006 C  CB  . THR A  1 253 ? -10.104 -38.081 28.446  1.000 27.891 0 276  THR A CB  1 ? 
ATOM   2007 O  OG1 . THR A  1 253 ? -10.189 -39.489 28.177  1.000 30.140 0 276  THR A OG1 1 ? 
ATOM   2008 C  CG2 . THR A  1 253 ? -9.734  -37.376 27.163  1.000 26.827 0 276  THR A CG2 1 ? 
ATOM   2009 N  N   . ILE A  1 254 ? -7.872  -35.754 29.220  1.000 22.978 0 277  ILE A N   1 ? 
ATOM   2010 C  CA  . ILE A  1 254 ? -7.601  -34.331 29.378  1.000 22.559 0 277  ILE A CA  1 ? 
ATOM   2011 C  C   . ILE A  1 254 ? -8.201  -33.612 28.172  1.000 21.827 0 277  ILE A C   1 ? 
ATOM   2012 O  O   . ILE A  1 254 ? -8.155  -34.133 27.055  1.000 20.349 0 277  ILE A O   1 ? 
ATOM   2013 C  CB  . ILE A  1 254 ? -6.092  -34.057 29.433  1.000 23.445 0 277  ILE A CB  1 ? 
ATOM   2014 C  CG1 . ILE A  1 254 ? -5.467  -34.689 30.667  1.000 24.359 0 277  ILE A CG1 1 ? 
ATOM   2015 C  CG2 . ILE A  1 254 ? -5.808  -32.540 29.355  1.000 25.346 0 277  ILE A CG2 1 ? 
ATOM   2016 C  CD1 . ILE A  1 254 ? -3.963  -34.664 30.635  1.000 23.633 0 277  ILE A CD1 1 ? 
ATOM   2017 N  N   . VAL A  1 255 ? -8.758  -32.425 28.410  1.000 20.480 0 278  VAL A N   1 ? 
ATOM   2018 C  CA  . VAL A  1 255 ? -9.303  -31.599 27.349  1.000 19.721 0 278  VAL A CA  1 ? 
ATOM   2019 C  C   . VAL A  1 255 ? -8.542  -30.286 27.332  1.000 18.257 0 278  VAL A C   1 ? 
ATOM   2020 O  O   . VAL A  1 255 ? -8.440  -29.636 28.386  1.000 19.916 0 278  VAL A O   1 ? 
ATOM   2021 C  CB  . VAL A  1 255 ? -10.799 -31.321 27.626  1.000 21.691 0 278  VAL A CB  1 ? 
ATOM   2022 C  CG1 . VAL A  1 255 ? -11.405 -30.497 26.514  1.000 20.031 0 278  VAL A CG1 1 ? 
ATOM   2023 C  CG2 . VAL A  1 255 ? -11.647 -32.586 27.871  1.000 22.060 0 278  VAL A CG2 1 ? 
ATOM   2024 N  N   . SER A  1 256 ? -8.116  -29.872 26.127  1.000 19.963 0 279  SER A N   1 ? 
ATOM   2025 C  CA  . SER A  1 256 ? -7.513  -28.582 25.877  1.000 19.157 0 279  SER A CA  1 ? 
ATOM   2026 C  C   . SER A  1 256 ? -8.442  -27.765 24.975  1.000 18.001 0 279  SER A C   1 ? 
ATOM   2027 O  O   . SER A  1 256 ? -8.805  -28.238 23.907  1.000 18.618 0 279  SER A O   1 ? 
ATOM   2028 C  CB  . SER A  1 256 ? -6.137  -28.750 25.261  1.000 18.824 0 279  SER A CB  1 ? 
ATOM   2029 O  OG  . SER A  1 256 ? -5.550  -27.481 24.952  1.000 18.595 0 279  SER A OG  1 ? 
ATOM   2030 N  N   . LEU A  1 257 ? -8.805  -26.551 25.420  1.000 17.230 0 280  LEU A N   1 ? 
ATOM   2031 C  CA  . LEU A  1 257 ? -9.633  -25.624 24.648  1.000 17.456 0 280  LEU A CA  1 ? 
ATOM   2032 C  C   . LEU A  1 257 ? -8.791  -24.384 24.422  1.000 16.609 0 280  LEU A C   1 ? 
ATOM   2033 O  O   . LEU A  1 257 ? -8.214  -23.894 25.376  1.000 17.972 0 280  LEU A O   1 ? 
ATOM   2034 C  CB  . LEU A  1 257 ? -10.898 -25.248 25.427  1.000 19.990 0 280  LEU A CB  1 ? 
ATOM   2035 C  CG  . LEU A  1 257 ? -11.735 -26.415 25.940  1.000 20.159 0 280  LEU A CG  1 ? 
ATOM   2036 C  CD1 . LEU A  1 257 ? -12.947 -25.923 26.699  1.000 21.778 0 280  LEU A CD1 1 ? 
ATOM   2037 C  CD2 . LEU A  1 257 ? -12.203 -27.258 24.760  1.000 21.354 0 280  LEU A CD2 1 ? 
ATOM   2038 N  N   . TRP A  1 258 ? -8.787  -23.847 23.210  1.000 17.168 0 281  TRP A N   1 ? 
ATOM   2039 C  CA  . TRP A  1 258 ? -7.997  -22.670 22.896  1.000 16.084 0 281  TRP A CA  1 ? 
ATOM   2040 C  C   . TRP A  1 258 ? -8.417  -22.149 21.539  1.000 17.517 0 281  TRP A C   1 ? 
ATOM   2041 O  O   . TRP A  1 258 ? -9.126  -22.842 20.825  1.000 17.422 0 281  TRP A O   1 ? 
ATOM   2042 C  CB  . TRP A  1 258 ? -6.480  -22.919 22.979  1.000 16.117 0 281  TRP A CB  1 ? 
ATOM   2043 C  CG  . TRP A  1 258 ? -5.857  -23.619 21.805  1.000 16.791 0 281  TRP A CG  1 ? 
ATOM   2044 C  CD1 . TRP A  1 258 ? -4.994  -23.081 20.918  1.000 17.511 0 281  TRP A CD1 1 ? 
ATOM   2045 C  CD2 . TRP A  1 258 ? -6.063  -24.993 21.404  1.000 16.226 0 281  TRP A CD2 1 ? 
ATOM   2046 N  NE1 . TRP A  1 258 ? -4.631  -24.024 20.000  1.000 18.053 0 281  TRP A NE1 1 ? 
ATOM   2047 C  CE2 . TRP A  1 258 ? -5.266  -25.196 20.267  1.000 16.770 0 281  TRP A CE2 1 ? 
ATOM   2048 C  CE3 . TRP A  1 258 ? -6.815  -26.055 21.918  1.000 16.737 0 281  TRP A CE3 1 ? 
ATOM   2049 C  CZ2 . TRP A  1 258 ? -5.223  -26.421 19.594  1.000 17.508 0 281  TRP A CZ2 1 ? 
ATOM   2050 C  CZ3 . TRP A  1 258 ? -6.763  -27.284 21.262  1.000 17.843 0 281  TRP A CZ3 1 ? 
ATOM   2051 C  CH2 . TRP A  1 258 ? -5.973  -27.447 20.122  1.000 18.162 0 281  TRP A CH2 1 ? 
ATOM   2052 N  N   . THR A  1 259 ? -7.903  -20.966 21.170  1.000 17.324 0 282  THR A N   1 ? 
ATOM   2053 C  CA  . THR A  1 259 ? -8.099  -20.417 19.836  1.000 15.660 0 282  THR A CA  1 ? 
ATOM   2054 C  C   . THR A  1 259 ? -6.892  -20.728 18.963  1.000 15.804 0 282  THR A C   1 ? 
ATOM   2055 O  O   . THR A  1 259 ? -5.848  -20.110 19.085  1.000 16.742 0 282  THR A O   1 ? 
ATOM   2056 C  CB  . THR A  1 259 ? -8.425  -18.917 19.921  1.000 15.773 0 282  THR A CB  1 ? 
ATOM   2057 O  OG1 . THR A  1 259 ? -9.654  -18.826 20.662  1.000 15.909 0 282  THR A OG1 1 ? 
ATOM   2058 C  CG2 . THR A  1 259 ? -8.572  -18.262 18.552  1.000 16.460 0 282  THR A CG2 1 ? 
ATOM   2059 N  N   . ASN A  1 260 ? -7.025  -21.749 18.107  1.000 16.161 0 283  ASN A N   1 ? 
ATOM   2060 C  CA  . ASN A  1 260 ? -5.909  -22.255 17.331  1.000 16.052 0 283  ASN A CA  1 ? 
ATOM   2061 C  C   . ASN A  1 260 ? -5.768  -21.464 16.031  1.000 15.470 0 283  ASN A C   1 ? 
ATOM   2062 O  O   . ASN A  1 260 ? -6.086  -21.975 14.958  1.000 15.717 0 283  ASN A O   1 ? 
ATOM   2063 C  CB  . ASN A  1 260 ? -6.089  -23.746 17.059  1.000 16.360 0 283  ASN A CB  1 ? 
ATOM   2064 C  CG  . ASN A  1 260 ? -4.775  -24.383 16.652  1.000 18.395 0 283  ASN A CG  1 ? 
ATOM   2065 O  OD1 . ASN A  1 260 ? -3.723  -24.000 17.157  1.000 18.062 0 283  ASN A OD1 1 ? 
ATOM   2066 N  ND2 . ASN A  1 260 ? -4.828  -25.337 15.738  1.000 17.265 0 283  ASN A ND2 1 ? 
ATOM   2067 N  N   . THR A  1 261 ? -5.276  -20.224 16.160  1.000 15.215 0 284  THR A N   1 ? 
ATOM   2068 C  CA  . THR A  1 261 ? -5.113  -19.315 15.041  1.000 16.734 0 284  THR A CA  1 ? 
ATOM   2069 C  C   . THR A  1 261 ? -3.706  -18.751 14.948  1.000 16.308 0 284  THR A C   1 ? 
ATOM   2070 O  O   . THR A  1 261 ? -2.941  -18.700 15.951  1.000 16.894 0 284  THR A O   1 ? 
ATOM   2071 C  CB  . THR A  1 261 ? -6.131  -18.191 15.146  1.000 16.597 0 284  THR A CB  1 ? 
ATOM   2072 O  OG1 . THR A  1 261 ? -5.860  -17.507 16.353  1.000 16.519 0 284  THR A OG1 1 ? 
ATOM   2073 C  CG2 . THR A  1 261 ? -7.552  -18.701 15.132  1.000 17.097 0 284  THR A CG2 1 ? 
ATOM   2074 N  N   . MET A  1 262 ? -3.398  -18.252 13.757  1.000 17.852 0 285  MET A N   1 ? 
ATOM   2075 C  CA  . MET A  1 262 ? -2.251  -17.381 13.556  1.000 20.375 0 285  MET A CA  1 ? 
ATOM   2076 C  C   . MET A  1 262 ? -2.759  -16.006 13.099  1.000 18.825 0 285  MET A C   1 ? 
ATOM   2077 O  O   . MET A  1 262 ? -3.483  -15.906 12.110  1.000 18.090 0 285  MET A O   1 ? 
ATOM   2078 C  CB  . MET A  1 262 ? -1.291  -17.947 12.509  1.000 19.215 0 285  MET A CB  1 ? 
ATOM   2079 C  CG  . MET A  1 262 ? -0.066  -17.084 12.252  1.000 21.722 0 285  MET A CG  1 ? 
ATOM   2080 S  SD  . MET A  1 262 ? 1.190   -17.242 13.568  1.000 20.588 0 285  MET A SD  1 ? 
ATOM   2081 C  CE  . MET A  1 262 ? 2.546   -16.343 12.814  1.000 21.031 0 285  MET A CE  1 ? 
ATOM   2082 N  N   . ALA A  1 263 ? -2.450  -14.974 13.881  1.000 18.348 0 286  ALA A N   1 ? 
ATOM   2083 C  CA  . ALA A  1 263 ? -2.761  -13.604 13.499  1.000 18.860 0 286  ALA A CA  1 ? 
ATOM   2084 C  C   . ALA A  1 263 ? -2.054  -13.221 12.205  1.000 19.109 0 286  ALA A C   1 ? 
ATOM   2085 O  O   . ALA A  1 263 ? -0.984  -13.736 11.889  1.000 18.556 0 286  ALA A O   1 ? 
ATOM   2086 C  CB  . ALA A  1 263 ? -2.349  -12.645 14.579  1.000 18.103 0 286  ALA A CB  1 ? 
ATOM   2087 N  N   . LEU A  1 264 ? -2.601  -12.206 11.527  1.000 19.384 0 287  LEU A N   1 ? 
ATOM   2088 C  CA  . LEU A  1 264 ? -1.877  -11.518 10.462  1.000 19.382 0 287  LEU A CA  1 ? 
ATOM   2089 C  C   . LEU A  1 264 ? -0.605  -10.895 11.030  1.000 18.987 0 287  LEU A C   1 ? 
ATOM   2090 O  O   . LEU A  1 264 ? -0.573  -10.444 12.189  1.000 19.340 0 287  LEU A O   1 ? 
ATOM   2091 C  CB  . LEU A  1 264 ? -2.770  -10.441 9.826   1.000 20.157 0 287  LEU A CB  1 ? 
ATOM   2092 C  CG  . LEU A  1 264 ? -3.843  -10.951 8.849   1.000 20.386 0 287  LEU A CG  1 ? 
ATOM   2093 C  CD1 . LEU A  1 264 ? -4.766  -9.831  8.418   1.000 21.600 0 287  LEU A CD1 1 ? 
ATOM   2094 C  CD2 . LEU A  1 264 ? -3.204  -11.571 7.615   1.000 22.382 0 287  LEU A CD2 1 ? 
ATOM   2095 N  N   . PRO A  1 265 ? 0.449   -10.752 10.201  1.000 19.673 0 288  PRO A N   1 ? 
ATOM   2096 C  CA  . PRO A  1 265 ? 1.657   -10.084 10.659  1.000 20.338 0 288  PRO A CA  1 ? 
ATOM   2097 C  C   . PRO A  1 265 ? 1.333   -8.647  11.066  1.000 21.517 0 288  PRO A C   1 ? 
ATOM   2098 O  O   . PRO A  1 265 ? 0.427   -8.023  10.516  1.000 20.258 0 288  PRO A O   1 ? 
ATOM   2099 C  CB  . PRO A  1 265 ? 2.603   -10.108 9.460   1.000 21.862 0 288  PRO A CB  1 ? 
ATOM   2100 C  CG  . PRO A  1 265 ? 2.025   -11.115 8.469   1.000 20.219 0 288  PRO A CG  1 ? 
ATOM   2101 C  CD  . PRO A  1 265 ? 0.552   -11.241 8.814   1.000 19.765 0 288  PRO A CD  1 ? 
ATOM   2102 N  N   . GLU A  1 266 ? 2.072   -8.136  12.060  1.000 19.432 0 289  GLU A N   1 ? 
ATOM   2103 C  CA  . GLU A  1 266 ? 1.953   -6.750  12.478  1.000 19.005 0 289  GLU A CA  1 ? 
ATOM   2104 C  C   . GLU A  1 266 ? 2.293   -5.831  11.307  1.000 19.407 0 289  GLU A C   1 ? 
ATOM   2105 O  O   . GLU A  1 266 ? 3.160   -6.146  10.465  1.000 21.759 0 289  GLU A O   1 ? 
ATOM   2106 C  CB  . GLU A  1 266 ? 2.865   -6.455  13.669  1.000 19.475 0 289  GLU A CB  1 ? 
ATOM   2107 C  CG  . GLU A  1 266 ? 2.471   -7.272  14.911  1.000 20.717 0 289  GLU A CG  1 ? 
ATOM   2108 C  CD  . GLU A  1 266 ? 1.016   -7.092  15.314  1.000 24.748 0 289  GLU A CD  1 ? 
ATOM   2109 O  OE1 . GLU A  1 266 ? 0.362   -8.137  15.541  1.000 23.586 0 289  GLU A OE1 1 ? 
ATOM   2110 O  OE2 . GLU A  1 266 ? 0.554   -5.917  15.458  1.000 24.286 0 289  GLU A OE2 1 ? 
ATOM   2111 N  N   . ASN A  1 267 ? 1.593   -4.696  11.299  1.000 19.626 0 290  ASN A N   1 ? 
ATOM   2112 C  CA  . ASN A  1 267 ? 1.747   -3.698  10.254  1.000 20.423 0 290  ASN A CA  1 ? 
ATOM   2113 C  C   . ASN A  1 267 ? 2.701   -2.594  10.732  1.000 21.790 0 290  ASN A C   1 ? 
ATOM   2114 O  O   . ASN A  1 267 ? 3.203   -2.621  11.857  1.000 23.195 0 290  ASN A O   1 ? 
ATOM   2115 C  CB  . ASN A  1 267 ? 0.373   -3.251  9.743   1.000 19.895 0 290  ASN A CB  1 ? 
ATOM   2116 C  CG  . ASN A  1 267 ? -0.411  -2.432  10.732  1.000 20.584 0 290  ASN A CG  1 ? 
ATOM   2117 O  OD1 . ASN A  1 267 ? 0.139   -1.553  11.411  1.000 20.799 0 290  ASN A OD1 1 ? 
ATOM   2118 N  ND2 . ASN A  1 267 ? -1.708  -2.695  10.790  1.000 20.858 0 290  ASN A ND2 1 ? 
ATOM   2119 N  N   . ALA A  1 268 ? 2.959   -1.621  9.845   1.000 23.085 0 291  ALA A N   1 ? 
ATOM   2120 C  CA  . ALA A  1 268 ? 3.918   -0.552  10.091  1.000 24.599 0 291  ALA A CA  1 ? 
ATOM   2121 C  C   . ALA A  1 268 ? 3.462   0.405   11.194  1.000 26.667 0 291  ALA A C   1 ? 
ATOM   2122 O  O   . ALA A  1 268 ? 4.278   1.198   11.692  1.000 27.045 0 291  ALA A O   1 ? 
ATOM   2123 C  CB  . ALA A  1 268 ? 4.191   0.207   8.799   1.000 25.105 0 291  ALA A CB  1 ? 
ATOM   2124 N  N   . THR A  1 269 ? 2.198   0.337   11.615  1.000 23.941 0 292  THR A N   1 ? 
ATOM   2125 C  CA  . THR A  1 269 ? 1.722   1.226   12.673  1.000 25.469 0 292  THR A CA  1 ? 
ATOM   2126 C  C   . THR A  1 269 ? 1.925   0.620   14.064  1.000 26.494 0 292  THR A C   1 ? 
ATOM   2127 O  O   . THR A  1 269 ? 1.734   1.303   15.058  1.000 29.613 0 292  THR A O   1 ? 
ATOM   2128 C  CB  . THR A  1 269 ? 0.250   1.631   12.533  1.000 27.526 0 292  THR A CB  1 ? 
ATOM   2129 O  OG1 . THR A  1 269 ? -0.616  0.559   12.944  1.000 29.025 0 292  THR A OG1 1 ? 
ATOM   2130 C  CG2 . THR A  1 269 ? -0.050  2.137   11.137  1.000 27.426 0 292  THR A CG2 1 ? 
ATOM   2131 N  N   . ALA A  1 270 ? 2.264   -0.666  14.137  1.000 25.723 0 293  ALA A N   1 ? 
ATOM   2132 C  CA  . ALA A  1 270 ? 2.397   -1.358  15.407  1.000 26.644 0 293  ALA A CA  1 ? 
ATOM   2133 C  C   . ALA A  1 270 ? 3.553   -0.763  16.214  1.000 26.683 0 293  ALA A C   1 ? 
ATOM   2134 O  O   . ALA A  1 270 ? 4.559   -0.282  15.651  1.000 29.230 0 293  ALA A O   1 ? 
ATOM   2135 C  CB  . ALA A  1 270 ? 2.589   -2.843  15.156  1.000 28.673 0 293  ALA A CB  1 ? 
ATOM   2136 N  N   . GLY A  1 271 ? 3.377   -0.790  17.538  1.000 28.634 0 294  GLY A N   1 ? 
ATOM   2137 C  CA  . GLY A  1 271 ? 4.304   -0.177  18.480  1.000 28.057 0 294  GLY A CA  1 ? 
ATOM   2138 C  C   . GLY A  1 271 ? 5.424   -1.113  18.936  1.000 26.937 0 294  GLY A C   1 ? 
ATOM   2139 O  O   . GLY A  1 271 ? 6.027   -1.820  18.139  1.000 29.435 0 294  GLY A O   1 ? 
ATOM   2140 N  N   . ASN A  1 272 ? 5.761   -1.036  20.227  1.000 27.141 0 295  ASN A N   1 ? 
ATOM   2141 C  CA  . ASN A  1 272 ? 6.987   -1.644  20.715  1.000 28.477 0 295  ASN A CA  1 ? 
ATOM   2142 C  C   . ASN A  1 272 ? 6.671   -2.693  21.780  1.000 25.138 0 295  ASN A C   1 ? 
ATOM   2143 O  O   . ASN A  1 272 ? 7.575   -3.213  22.445  1.000 26.692 0 295  ASN A O   1 ? 
ATOM   2144 C  CB  . ASN A  1 272 ? 7.911   -0.570  21.289  1.000 30.847 0 295  ASN A CB  1 ? 
ATOM   2145 C  CG  . ASN A  1 272 ? 7.333   0.040   22.552  1.000 34.516 0 295  ASN A CG  1 ? 
ATOM   2146 O  OD1 . ASN A  1 272 ? 6.134   -0.095  22.853  1.000 33.019 0 295  ASN A OD1 1 ? 
ATOM   2147 N  ND2 . ASN A  1 272 ? 8.185   0.723   23.301  1.000 33.755 0 295  ASN A ND2 1 ? 
ATOM   2148 N  N   . GLY A  1 273 ? 5.380   -2.984  21.940  1.000 23.368 0 296  GLY A N   1 ? 
ATOM   2149 C  CA  . GLY A  1 273 ? 4.927   -3.961  22.915  1.000 23.258 0 296  GLY A CA  1 ? 
ATOM   2150 C  C   . GLY A  1 273 ? 4.020   -3.366  23.979  1.000 24.295 0 296  GLY A C   1 ? 
ATOM   2151 O  O   . GLY A  1 273 ? 3.451   -4.112  24.785  1.000 22.596 0 296  GLY A O   1 ? 
ATOM   2152 N  N   . THR A  1 274 ? 3.898   -2.020  24.016  1.000 22.469 0 297  THR A N   1 ? 
ATOM   2153 C  CA  . THR A  1 274 ? 3.138   -1.357  25.057  1.000 23.596 0 297  THR A CA  1 ? 
ATOM   2154 C  C   . THR A  1 274 ? 1.636   -1.590  24.921  1.000 22.447 0 297  THR A C   1 ? 
ATOM   2155 O  O   . THR A  1 274 ? 0.891   -1.560  25.905  1.000 23.705 0 297  THR A O   1 ? 
ATOM   2156 C  CB  . THR A  1 274 ? 3.443   0.165   25.027  1.000 28.482 0 297  THR A CB  1 ? 
ATOM   2157 O  OG1 . THR A  1 274 ? 4.862   0.347   25.070  1.000 32.281 0 297  THR A OG1 1 ? 
ATOM   2158 C  CG2 . THR A  1 274 ? 2.822   0.908   26.183  1.000 34.398 0 297  THR A CG2 1 ? 
ATOM   2159 N  N   . TRP A  1 275 ? 1.160   -1.699  23.675  1.000 21.937 0 298  TRP A N   1 ? 
ATOM   2160 C  CA  . TRP A  1 275 ? -0.273  -1.678  23.393  1.000 22.136 0 298  TRP A CA  1 ? 
ATOM   2161 C  C   . TRP A  1 275 ? -0.481  -2.400  22.061  1.000 20.585 0 298  TRP A C   1 ? 
ATOM   2162 O  O   . TRP A  1 275 ? 0.379   -2.327  21.184  1.000 23.991 0 298  TRP A O   1 ? 
ATOM   2163 C  CB  . TRP A  1 275 ? -0.718  -0.197  23.376  1.000 21.595 0 298  TRP A CB  1 ? 
ATOM   2164 C  CG  . TRP A  1 275 ? -2.173  0.150   23.526  1.000 22.916 0 298  TRP A CG  1 ? 
ATOM   2165 C  CD1 . TRP A  1 275 ? -3.192  -0.149  22.666  1.000 26.324 0 298  TRP A CD1 1 ? 
ATOM   2166 C  CD2 . TRP A  1 275 ? -2.761  0.976   24.555  1.000 23.860 0 298  TRP A CD2 1 ? 
ATOM   2167 N  NE1 . TRP A  1 275 ? -4.372  0.373   23.115  1.000 26.728 0 298  TRP A NE1 1 ? 
ATOM   2168 C  CE2 . TRP A  1 275 ? -4.140  1.093   24.256  1.000 25.432 0 298  TRP A CE2 1 ? 
ATOM   2169 C  CE3 . TRP A  1 275 ? -2.268  1.610   25.696  1.000 23.802 0 298  TRP A CE3 1 ? 
ATOM   2170 C  CZ2 . TRP A  1 275 ? -5.019  1.833   25.042  1.000 27.802 0 298  TRP A CZ2 1 ? 
ATOM   2171 C  CZ3 . TRP A  1 275 ? -3.143  2.334   26.479  1.000 25.396 0 298  TRP A CZ3 1 ? 
ATOM   2172 C  CH2 . TRP A  1 275 ? -4.501  2.446   26.164  1.000 27.386 0 298  TRP A CH2 1 ? 
ATOM   2173 N  N   . GLU A  1 276 ? -1.591  -3.105  21.907  1.000 22.666 0 299  GLU A N   1 ? 
ATOM   2174 C  CA  . GLU A  1 276 ? -1.833  -3.800  20.653  1.000 25.726 0 299  GLU A CA  1 ? 
ATOM   2175 C  C   . GLU A  1 276 ? -2.321  -2.833  19.582  1.000 23.350 0 299  GLU A C   1 ? 
ATOM   2176 O  O   . GLU A  1 276 ? -2.685  -1.704  19.870  1.000 23.256 0 299  GLU A O   1 ? 
ATOM   2177 C  CB  . GLU A  1 276 ? -2.846  -4.954  20.725  1.000 29.270 0 299  GLU A CB  1 ? 
ATOM   2178 C  CG  . GLU A  1 276 ? -4.262  -4.734  21.293  1.000 31.717 0 299  GLU A CG  1 ? 
ATOM   2179 C  CD  . GLU A  1 276 ? -4.665  -3.763  22.396  1.000 28.518 0 299  GLU A CD  1 ? 
ATOM   2180 O  OE1 . GLU A  1 276 ? -5.843  -3.433  22.435  1.000 29.487 0 299  GLU A OE1 1 ? 
ATOM   2181 O  OE2 . GLU A  1 276 ? -3.879  -3.525  23.282  1.000 24.490 0 299  GLU A OE2 1 ? 
ATOM   2182 N  N   . ASP A  1 277 ? -2.309  -3.319  18.345  1.000 20.687 0 300  ASP A N   1 ? 
ATOM   2183 C  CA  . ASP A  1 277 ? -2.840  -2.593  17.203  1.000 22.531 0 300  ASP A CA  1 ? 
ATOM   2184 C  C   . ASP A  1 277 ? -4.270  -3.105  16.970  1.000 23.263 0 300  ASP A C   1 ? 
ATOM   2185 O  O   . ASP A  1 277 ? -5.246  -2.462  17.412  1.000 22.246 0 300  ASP A O   1 ? 
ATOM   2186 C  CB  . ASP A  1 277 ? -1.911  -2.732  15.997  1.000 23.452 0 300  ASP A CB  1 ? 
ATOM   2187 C  CG  . ASP A  1 277 ? -2.420  -1.991  14.765  1.000 23.995 0 300  ASP A CG  1 ? 
ATOM   2188 O  OD1 . ASP A  1 277 ? -3.292  -1.114  14.928  1.000 24.704 0 300  ASP A OD1 1 ? 
ATOM   2189 O  OD2 . ASP A  1 277 ? -2.023  -2.366  13.657  1.000 26.216 0 300  ASP A OD2 1 ? 
ATOM   2190 N  N   A VAL A  1 278 ? -4.358  -4.337  16.437  0.500 21.591 0 301  VAL A N   1 ? 
ATOM   2191 N  N   B VAL A  1 278 ? -4.381  -4.295  16.348  0.500 20.119 0 301  VAL A N   1 ? 
ATOM   2192 C  CA  A VAL A  1 278 ? -5.610  -4.935  16.015  0.500 22.159 0 301  VAL A CA  1 ? 
ATOM   2193 C  CA  B VAL A  1 278 ? -5.663  -4.922  16.067  0.500 19.538 0 301  VAL A CA  1 ? 
ATOM   2194 C  C   A VAL A  1 278 ? -5.552  -6.444  16.274  0.500 22.473 0 301  VAL A C   1 ? 
ATOM   2195 C  C   B VAL A  1 278 ? -5.557  -6.431  16.305  0.500 21.056 0 301  VAL A C   1 ? 
ATOM   2196 O  O   A VAL A  1 278 ? -4.477  -7.050  16.228  0.500 21.065 0 301  VAL A O   1 ? 
ATOM   2197 O  O   B VAL A  1 278 ? -4.472  -7.021  16.248  0.500 19.855 0 301  VAL A O   1 ? 
ATOM   2198 C  CB  A VAL A  1 278 ? -5.847  -4.617  14.527  0.500 27.182 0 301  VAL A CB  1 ? 
ATOM   2199 C  CB  B VAL A  1 278 ? -6.130  -4.638  14.626  0.500 21.490 0 301  VAL A CB  1 ? 
ATOM   2200 C  CG1 A VAL A  1 278 ? -4.790  -5.266  13.634  0.500 28.306 0 301  VAL A CG1 1 ? 
ATOM   2201 C  CG1 B VAL A  1 278 ? -6.641  -3.207  14.461  0.500 19.932 0 301  VAL A CG1 1 ? 
ATOM   2202 C  CG2 A VAL A  1 278 ? -7.243  -4.979  14.074  0.500 28.989 0 301  VAL A CG2 1 ? 
ATOM   2203 C  CG2 B VAL A  1 278 ? -5.023  -4.952  13.620  0.500 23.427 0 301  VAL A CG2 1 ? 
ATOM   2204 N  N   . PHE A  1 279 ? -6.712  -7.026  16.587  1.000 19.257 0 302  PHE A N   1 ? 
ATOM   2205 C  CA  . PHE A  1 279 ? -6.863  -8.462  16.667  1.000 19.866 0 302  PHE A CA  1 ? 
ATOM   2206 C  C   . PHE A  1 279 ? -7.379  -9.011  15.343  1.000 19.312 0 302  PHE A C   1 ? 
ATOM   2207 O  O   . PHE A  1 279 ? -8.485  -8.641  14.895  1.000 21.613 0 302  PHE A O   1 ? 
ATOM   2208 C  CB  . PHE A  1 279 ? -7.813  -8.815  17.797  1.000 23.348 0 302  PHE A CB  1 ? 
ATOM   2209 C  CG  . PHE A  1 279 ? -7.171  -8.649  19.154  1.000 26.391 0 302  PHE A CG  1 ? 
ATOM   2210 C  CD1 . PHE A  1 279 ? -6.251  -9.578  19.605  1.000 34.453 0 302  PHE A CD1 1 ? 
ATOM   2211 C  CD2 . PHE A  1 279 ? -7.523  -7.621  19.989  1.000 33.194 0 302  PHE A CD2 1 ? 
ATOM   2212 C  CE1 . PHE A  1 279 ? -5.670  -9.440  20.857  1.000 38.073 0 302  PHE A CE1 1 ? 
ATOM   2213 C  CE2 . PHE A  1 279 ? -6.927  -7.470  21.235  1.000 33.629 0 302  PHE A CE2 1 ? 
ATOM   2214 C  CZ  . PHE A  1 279 ? -5.972  -8.352  21.646  1.000 33.259 0 302  PHE A CZ  1 ? 
ATOM   2215 N  N   . THR A  1 280 ? -6.626  -9.975  14.785  1.000 18.232 0 303  THR A N   1 ? 
ATOM   2216 C  CA  . THR A  1 280 ? -7.005  -10.644 13.549  1.000 17.056 0 303  THR A CA  1 ? 
ATOM   2217 C  C   . THR A  1 280 ? -7.062  -12.162 13.737  1.000 16.887 0 303  THR A C   1 ? 
ATOM   2218 O  O   . THR A  1 280 ? -6.815  -12.893 12.795  1.000 17.328 0 303  THR A O   1 ? 
ATOM   2219 C  CB  . THR A  1 280 ? -6.074  -10.247 12.393  1.000 20.411 0 303  THR A CB  1 ? 
ATOM   2220 O  OG1 . THR A  1 280 ? -4.710  -10.585 12.672  1.000 20.347 0 303  THR A OG1 1 ? 
ATOM   2221 C  CG2 . THR A  1 280 ? -6.177  -8.768  12.075  1.000 22.698 0 303  THR A CG2 1 ? 
ATOM   2222 N  N   . ASN A  1 281 ? -7.394  -12.637 14.937  1.000 16.860 0 304  ASN A N   1 ? 
ATOM   2223 C  CA  . ASN A  1 281 ? -7.141  -14.017 15.270  1.000 17.825 0 304  ASN A CA  1 ? 
ATOM   2224 C  C   . ASN A  1 281 ? -8.116  -14.574 16.294  1.000 17.690 0 304  ASN A C   1 ? 
ATOM   2225 O  O   . ASN A  1 281 ? -7.797  -15.597 16.885  1.000 17.374 0 304  ASN A O   1 ? 
ATOM   2226 C  CB  . ASN A  1 281 ? -5.709  -14.185 15.785  1.000 18.455 0 304  ASN A CB  1 ? 
ATOM   2227 C  CG  . ASN A  1 281 ? -5.491  -13.464 17.099  1.000 20.703 0 304  ASN A CG  1 ? 
ATOM   2228 O  OD1 . ASN A  1 281 ? -6.182  -12.508 17.402  1.000 21.981 0 304  ASN A OD1 1 ? 
ATOM   2229 N  ND2 . ASN A  1 281 ? -4.559  -13.938 17.906  1.000 23.844 0 304  ASN A ND2 1 ? 
ATOM   2230 N  N   . ARG A  1 282 ? -9.325  -13.991 16.464  1.000 18.020 0 305  ARG A N   1 ? 
ATOM   2231 C  CA  . ARG A  1 282 ? -10.213 -14.458 17.508  1.000 17.894 0 305  ARG A CA  1 ? 
ATOM   2232 C  C   . ARG A  1 282 ? -11.577 -14.912 16.982  1.000 18.477 0 305  ARG A C   1 ? 
ATOM   2233 O  O   . ARG A  1 282 ? -12.560 -14.806 17.694  1.000 18.843 0 305  ARG A O   1 ? 
ATOM   2234 C  CB  . ARG A  1 282 ? -10.423 -13.309 18.502  1.000 19.594 0 305  ARG A CB  1 ? 
ATOM   2235 C  CG  . ARG A  1 282 ? -9.136  -12.882 19.194  1.000 21.975 0 305  ARG A CG  1 ? 
ATOM   2236 C  CD  . ARG A  1 282 ? -9.495  -11.917 20.306  1.000 25.223 0 305  ARG A CD  1 ? 
ATOM   2237 N  NE  . ARG A  1 282 ? -8.438  -11.945 21.308  1.000 34.210 0 305  ARG A NE  1 ? 
ATOM   2238 C  CZ  . ARG A  1 282 ? -8.518  -11.325 22.486  1.000 37.222 0 305  ARG A CZ  1 ? 
ATOM   2239 N  NH1 . ARG A  1 282 ? -9.579  -10.580 22.771  1.000 33.162 0 305  ARG A NH1 1 ? 
ATOM   2240 N  NH2 . ARG A  1 282 ? -7.514  -11.413 23.338  1.000 28.366 0 305  ARG A NH2 1 ? 
ATOM   2241 N  N   . ASP A  1 283 ? -11.630 -15.525 15.800  1.000 19.935 0 306  ASP A N   1 ? 
ATOM   2242 C  CA  . ASP A  1 283 ? -12.904 -15.882 15.201  1.000 18.635 0 306  ASP A CA  1 ? 
ATOM   2243 C  C   . ASP A  1 283 ? -13.112 -17.401 15.147  1.000 17.903 0 306  ASP A C   1 ? 
ATOM   2244 O  O   . ASP A  1 283 ? -13.910 -17.868 14.343  1.000 16.993 0 306  ASP A O   1 ? 
ATOM   2245 C  CB  . ASP A  1 283 ? -13.039 -15.217 13.847  1.000 18.903 0 306  ASP A CB  1 ? 
ATOM   2246 C  CG  . ASP A  1 283 ? -13.239 -13.712 14.007  1.000 21.151 0 306  ASP A CG  1 ? 
ATOM   2247 O  OD1 . ASP A  1 283 ? -14.222 -13.325 14.664  1.000 21.555 0 306  ASP A OD1 1 ? 
ATOM   2248 O  OD2 . ASP A  1 283 ? -12.398 -12.968 13.491  1.000 20.373 0 306  ASP A OD2 1 ? 
ATOM   2249 N  N   . SER A  1 284 ? -12.567 -18.106 16.148  1.000 17.252 0 307  SER A N   1 ? 
ATOM   2250 C  CA  . SER A  1 284 ? -12.694 -19.550 16.238  1.000 16.811 0 307  SER A CA  1 ? 
ATOM   2251 C  C   . SER A  1 284 ? -12.327 -20.002 17.639  1.000 18.895 0 307  SER A C   1 ? 
ATOM   2252 O  O   . SER A  1 284 ? -11.665 -19.276 18.381  1.000 16.658 0 307  SER A O   1 ? 
ATOM   2253 C  CB  . SER A  1 284 ? -11.859 -20.246 15.181  1.000 17.677 0 307  SER A CB  1 ? 
ATOM   2254 O  OG  . SER A  1 284 ? -10.481 -19.902 15.293  1.000 16.088 0 307  SER A OG  1 ? 
ATOM   2255 N  N   . HIS A  1 285 ? -12.743 -21.232 17.984  1.000 17.827 0 308  HIS A N   1 ? 
ATOM   2256 C  CA  . HIS A  1 285 ? -12.262 -21.888 19.185  1.000 16.584 0 308  HIS A CA  1 ? 
ATOM   2257 C  C   . HIS A  1 285 ? -12.143 -23.367 18.840  1.000 18.352 0 308  HIS A C   1 ? 
ATOM   2258 O  O   . HIS A  1 285 ? -12.901 -23.847 17.988  1.000 18.543 0 308  HIS A O   1 ? 
ATOM   2259 C  CB  . HIS A  1 285 ? -13.233 -21.690 20.356  1.000 18.174 0 308  HIS A CB  1 ? 
ATOM   2260 C  CG  . HIS A  1 285 ? -12.599 -21.677 21.663  1.000 20.932 0 308  HIS A CG  1 ? 
ATOM   2261 N  ND1 . HIS A  1 285 ? -12.270 -20.491 22.293  1.000 18.638 0 308  HIS A ND1 1 ? 
ATOM   2262 C  CD2 . HIS A  1 285 ? -12.166 -22.671 22.467  1.000 19.459 0 308  HIS A CD2 1 ? 
ATOM   2263 C  CE1 . HIS A  1 285 ? -11.611 -20.791 23.417  1.000 19.259 0 308  HIS A CE1 1 ? 
ATOM   2264 N  NE2 . HIS A  1 285 ? -11.577 -22.084 23.565  1.000 17.940 0 308  HIS A NE2 1 ? 
ATOM   2265 N  N   . HIS A  1 286 ? -11.169 -24.050 19.480  1.000 18.290 0 309  HIS A N   1 ? 
ATOM   2266 C  CA  . HIS A  1 286 ? -10.789 -25.412 19.121  1.000 16.621 0 309  HIS A CA  1 ? 
ATOM   2267 C  C   . HIS A  1 286 ? -10.707 -26.306 20.346  1.000 18.591 0 309  HIS A C   1 ? 
ATOM   2268 O  O   . HIS A  1 286 ? -10.605 -25.817 21.471  1.000 18.279 0 309  HIS A O   1 ? 
ATOM   2269 C  CB  . HIS A  1 286 ? -9.399  -25.424 18.461  1.000 16.255 0 309  HIS A CB  1 ? 
ATOM   2270 C  CG  . HIS A  1 286 ? -9.360  -24.642 17.208  1.000 16.978 0 309  HIS A CG  1 ? 
ATOM   2271 N  ND1 . HIS A  1 286 ? -9.366  -23.259 17.147  1.000 17.221 0 309  HIS A ND1 1 ? 
ATOM   2272 C  CD2 . HIS A  1 286 ? -9.322  -25.079 15.951  1.000 16.572 0 309  HIS A CD2 1 ? 
ATOM   2273 C  CE1 . HIS A  1 286 ? -9.311  -22.886 15.887  1.000 16.885 0 309  HIS A CE1 1 ? 
ATOM   2274 N  NE2 . HIS A  1 286 ? -9.322  -23.979 15.133  1.000 16.077 0 309  HIS A NE2 1 ? 
ATOM   2275 N  N   . ILE A  1 287 ? -10.743 -27.629 20.098  1.000 17.850 0 310  ILE A N   1 ? 
ATOM   2276 C  CA  . ILE A  1 287 ? -10.653 -28.622 21.155  1.000 17.180 0 310  ILE A CA  1 ? 
ATOM   2277 C  C   . ILE A  1 287 ? -9.687  -29.733 20.742  1.000 20.355 0 310  ILE A C   1 ? 
ATOM   2278 O  O   . ILE A  1 287 ? -9.737  -30.199 19.601  1.000 18.727 0 310  ILE A O   1 ? 
ATOM   2279 C  CB  . ILE A  1 287 ? -12.047 -29.190 21.498  1.000 19.537 0 310  ILE A CB  1 ? 
ATOM   2280 C  CG1 . ILE A  1 287 ? -11.954 -30.315 22.544  1.000 20.864 0 310  ILE A CG1 1 ? 
ATOM   2281 C  CG2 . ILE A  1 287 ? -12.837 -29.633 20.265  1.000 19.749 0 310  ILE A CG2 1 ? 
ATOM   2282 C  CD1 . ILE A  1 287 ? -13.270 -30.607 23.234  1.000 20.778 0 310  ILE A CD1 1 ? 
ATOM   2283 N  N   . ALA A  1 288 ? -8.852  -30.176 21.703  1.000 21.397 0 311  ALA A N   1 ? 
ATOM   2284 C  CA  . ALA A  1 288 ? -8.029  -31.381 21.553  1.000 20.114 0 311  ALA A CA  1 ? 
ATOM   2285 C  C   . ALA A  1 288 ? -8.118  -32.166 22.850  1.000 21.622 0 311  ALA A C   1 ? 
ATOM   2286 O  O   . ALA A  1 288 ? -8.374  -31.605 23.915  1.000 18.199 0 311  ALA A O   1 ? 
ATOM   2287 C  CB  . ALA A  1 288 ? -6.605  -31.043 21.230  1.000 20.172 0 311  ALA A CB  1 ? 
ATOM   2288 N  N   . MET A  1 289 ? -7.942  -33.480 22.757  1.000 18.668 0 312  MET A N   1 ? 
ATOM   2289 C  CA  . MET A  1 289 ? -8.057  -34.337 23.912  1.000 19.442 0 312  MET A CA  1 ? 
ATOM   2290 C  C   . MET A  1 289 ? -6.850  -35.270 23.962  1.000 19.493 0 312  MET A C   1 ? 
ATOM   2291 O  O   . MET A  1 289 ? -6.176  -35.524 22.962  1.000 20.986 0 312  MET A O   1 ? 
ATOM   2292 C  CB  . MET A  1 289 ? -9.376  -35.117 23.869  1.000 20.895 0 312  MET A CB  1 ? 
ATOM   2293 C  CG  . MET A  1 289 ? -10.566 -34.273 24.203  1.000 22.757 0 312  MET A CG  1 ? 
ATOM   2294 S  SD  . MET A  1 289 ? -12.192 -35.051 23.952  1.000 27.835 0 312  MET A SD  1 ? 
ATOM   2295 C  CE  . MET A  1 289 ? -12.209 -36.260 25.254  1.000 36.277 0 312  MET A CE  1 ? 
ATOM   2296 N  N   . SER A  1 290 ? -6.554  -35.763 25.175  1.000 23.134 0 313  SER A N   1 ? 
ATOM   2297 C  CA  . SER A  1 290 ? -5.486  -36.723 25.368  1.000 23.358 0 313  SER A CA  1 ? 
ATOM   2298 C  C   . SER A  1 290 ? -5.901  -37.746 26.419  1.000 24.594 0 313  SER A C   1 ? 
ATOM   2299 O  O   . SER A  1 290 ? -6.330  -37.381 27.510  1.000 22.349 0 313  SER A O   1 ? 
ATOM   2300 C  CB  . SER A  1 290 ? -4.208  -36.057 25.800  1.000 25.532 0 313  SER A CB  1 ? 
ATOM   2301 O  OG  . SER A  1 290 ? -3.235  -37.056 26.157  1.000 23.604 0 313  SER A OG  1 ? 
ATOM   2302 N  N   . GLY A  1 291 ? -5.712  -39.030 26.094  1.000 26.754 0 314  GLY A N   1 ? 
ATOM   2303 C  CA  . GLY A  1 291 ? -5.970  -40.089 27.054  1.000 27.911 0 314  GLY A CA  1 ? 
ATOM   2304 C  C   . GLY A  1 291 ? -4.733  -40.633 27.772  1.000 28.207 0 314  GLY A C   1 ? 
ATOM   2305 O  O   . GLY A  1 291 ? -4.854  -41.586 28.552  1.000 31.769 0 314  GLY A O   1 ? 
ATOM   2306 N  N   . ASP A  1 292 ? -3.577  -39.998 27.598  1.000 28.942 0 315  ASP A N   1 ? 
ATOM   2307 C  CA  . ASP A  1 292 ? -2.340  -40.491 28.200  1.000 29.379 0 315  ASP A CA  1 ? 
ATOM   2308 C  C   . ASP A  1 292 ? -1.494  -39.368 28.807  1.000 23.789 0 315  ASP A C   1 ? 
ATOM   2309 O  O   . ASP A  1 292 ? -0.280  -39.292 28.641  1.000 24.172 0 315  ASP A O   1 ? 
ATOM   2310 C  CB  . ASP A  1 292 ? -1.552  -41.238 27.139  1.000 31.397 0 315  ASP A CB  1 ? 
ATOM   2311 C  CG  . ASP A  1 292 ? -1.243  -40.420 25.904  1.000 35.401 0 315  ASP A CG  1 ? 
ATOM   2312 O  OD1 . ASP A  1 292 ? -1.389  -39.154 25.935  1.000 25.961 0 315  ASP A OD1 1 ? 
ATOM   2313 O  OD2 . ASP A  1 292 ? -0.871  -41.061 24.914  1.000 32.628 0 315  ASP A OD2 1 ? 
ATOM   2314 N  N   . GLU A  1 293 ? -2.147  -38.493 29.560  1.000 26.748 0 316  GLU A N   1 ? 
ATOM   2315 C  CA  . GLU A  1 293 ? -1.445  -37.452 30.273  1.000 25.096 0 316  GLU A CA  1 ? 
ATOM   2316 C  C   . GLU A  1 293 ? -0.618  -36.607 29.311  1.000 24.700 0 316  GLU A C   1 ? 
ATOM   2317 O  O   . GLU A  1 293 ? 0.448   -36.124 29.680  1.000 25.378 0 316  GLU A O   1 ? 
ATOM   2318 C  CB  . GLU A  1 293 ? -0.607  -38.028 31.420  1.000 28.222 0 316  GLU A CB  1 ? 
ATOM   2319 C  CG  . GLU A  1 293 ? -1.488  -38.609 32.497  1.000 28.504 0 316  GLU A CG  1 ? 
ATOM   2320 C  CD  . GLU A  1 293 ? -2.576  -37.657 32.979  1.000 27.351 0 316  GLU A CD  1 ? 
ATOM   2321 O  OE1 . GLU A  1 293 ? -2.253  -36.768 33.793  1.000 26.801 0 316  GLU A OE1 1 ? 
ATOM   2322 O  OE2 . GLU A  1 293 ? -3.761  -37.836 32.590  1.000 29.523 0 316  GLU A OE2 1 ? 
ATOM   2323 N  N   . GLY A  1 294 ? -1.165  -36.371 28.114  1.000 23.625 0 317  GLY A N   1 ? 
ATOM   2324 C  CA  . GLY A  1 294 ? -0.616  -35.386 27.202  1.000 23.623 0 317  GLY A CA  1 ? 
ATOM   2325 C  C   . GLY A  1 294 ? 0.550   -35.880 26.341  1.000 26.799 0 317  GLY A C   1 ? 
ATOM   2326 O  O   . GLY A  1 294 ? 1.151   -35.077 25.646  1.000 26.950 0 317  GLY A O   1 ? 
ATOM   2327 N  N   . LYS A  1 295 ? 0.865   -37.181 26.358  1.000 27.287 0 318  LYS A N   1 ? 
ATOM   2328 C  CA  . LYS A  1 295 ? 1.908   -37.701 25.482  1.000 29.964 0 318  LYS A CA  1 ? 
ATOM   2329 C  C   . LYS A  1 295 ? 1.412   -37.724 24.030  1.000 28.455 0 318  LYS A C   1 ? 
ATOM   2330 O  O   . LYS A  1 295 ? 2.195   -37.426 23.120  1.000 28.454 0 318  LYS A O   1 ? 
ATOM   2331 C  CB  . LYS A  1 295 ? 2.368   -39.071 25.987  1.000 32.568 0 318  LYS A CB  1 ? 
ATOM   2332 C  CG  . LYS A  1 295 ? 3.048   -38.956 27.351  1.000 35.981 0 318  LYS A CG  1 ? 
ATOM   2333 C  CD  . LYS A  1 295 ? 3.786   -40.162 27.842  1.000 40.439 0 318  LYS A CD  1 ? 
ATOM   2334 C  CE  . LYS A  1 295 ? 2.858   -41.233 28.365  1.000 43.468 0 318  LYS A CE  1 ? 
ATOM   2335 N  NZ  . LYS A  1 295 ? 2.172   -40.856 29.623  1.000 45.534 0 318  LYS A NZ  1 ? 
ATOM   2336 N  N   . THR A  1 296 ? 0.102   -37.953 23.833  1.000 27.986 0 319  THR A N   1 ? 
ATOM   2337 C  CA  . THR A  1 296 ? -0.477  -37.829 22.501  1.000 27.348 0 319  THR A CA  1 ? 
ATOM   2338 C  C   . THR A  1 296 ? -1.826  -37.112 22.562  1.000 25.436 0 319  THR A C   1 ? 
ATOM   2339 O  O   . THR A  1 296 ? -2.565  -37.198 23.536  1.000 24.923 0 319  THR A O   1 ? 
ATOM   2340 C  CB  . THR A  1 296 ? -0.667  -39.187 21.809  1.000 31.181 0 319  THR A CB  1 ? 
ATOM   2341 O  OG1 . THR A  1 296 ? -1.647  -39.891 22.550  1.000 31.724 0 319  THR A OG1 1 ? 
ATOM   2342 C  CG2 . THR A  1 296 ? 0.594   -40.024 21.763  1.000 34.944 0 319  THR A CG2 1 ? 
ATOM   2343 N  N   . TRP A  1 297 ? -2.137  -36.398 21.472  1.000 23.916 0 320  TRP A N   1 ? 
ATOM   2344 C  CA  . TRP A  1 297 ? -3.338  -35.580 21.382  1.000 24.180 0 320  TRP A CA  1 ? 
ATOM   2345 C  C   . TRP A  1 297 ? -4.076  -35.878 20.088  1.000 23.217 0 320  TRP A C   1 ? 
ATOM   2346 O  O   . TRP A  1 297 ? -3.436  -36.184 19.085  1.000 24.693 0 320  TRP A O   1 ? 
ATOM   2347 C  CB  . TRP A  1 297 ? -2.935  -34.100 21.419  1.000 24.369 0 320  TRP A CB  1 ? 
ATOM   2348 C  CG  . TRP A  1 297 ? -2.339  -33.668 22.729  1.000 22.095 0 320  TRP A CG  1 ? 
ATOM   2349 C  CD1 . TRP A  1 297 ? -1.032  -33.751 23.109  1.000 23.032 0 320  TRP A CD1 1 ? 
ATOM   2350 C  CD2 . TRP A  1 297 ? -3.057  -33.094 23.845  1.000 23.203 0 320  TRP A CD2 1 ? 
ATOM   2351 N  NE1 . TRP A  1 297 ? -0.883  -33.296 24.393  1.000 22.641 0 320  TRP A NE1 1 ? 
ATOM   2352 C  CE2 . TRP A  1 297 ? -2.102  -32.895 24.866  1.000 21.274 0 320  TRP A CE2 1 ? 
ATOM   2353 C  CE3 . TRP A  1 297 ? -4.398  -32.751 24.088  1.000 22.232 0 320  TRP A CE3 1 ? 
ATOM   2354 C  CZ2 . TRP A  1 297 ? -2.445  -32.331 26.087  1.000 21.815 0 320  TRP A CZ2 1 ? 
ATOM   2355 C  CZ3 . TRP A  1 297 ? -4.732  -32.162 25.289  1.000 22.827 0 320  TRP A CZ3 1 ? 
ATOM   2356 C  CH2 . TRP A  1 297 ? -3.765  -32.003 26.291  1.000 22.860 0 320  TRP A CH2 1 ? 
ATOM   2357 N  N   . TYR A  1 298 ? -5.393  -35.702 20.123  1.000 23.829 0 321  TYR A N   1 ? 
ATOM   2358 C  CA  . TYR A  1 298 ? -6.230  -35.864 18.951  1.000 25.158 0 321  TYR A CA  1 ? 
ATOM   2359 C  C   . TYR A  1 298 ? -7.305  -34.785 18.926  1.000 25.128 0 321  TYR A C   1 ? 
ATOM   2360 O  O   . TYR A  1 298 ? -7.649  -34.203 19.944  1.000 24.320 0 321  TYR A O   1 ? 
ATOM   2361 C  CB  . TYR A  1 298 ? -6.913  -37.239 18.960  1.000 22.538 0 321  TYR A CB  1 ? 
ATOM   2362 C  CG  . TYR A  1 298 ? -7.795  -37.567 20.152  1.000 22.664 0 321  TYR A CG  1 ? 
ATOM   2363 C  CD1 . TYR A  1 298 ? -9.161  -37.314 20.147  1.000 25.010 0 321  TYR A CD1 1 ? 
ATOM   2364 C  CD2 . TYR A  1 298 ? -7.276  -38.187 21.285  1.000 23.848 0 321  TYR A CD2 1 ? 
ATOM   2365 C  CE1 . TYR A  1 298 ? -9.971  -37.639 21.227  1.000 23.232 0 321  TYR A CE1 1 ? 
ATOM   2366 C  CE2 . TYR A  1 298 ? -8.091  -38.551 22.347  1.000 23.115 0 321  TYR A CE2 1 ? 
ATOM   2367 C  CZ  . TYR A  1 298 ? -9.430  -38.254 22.342  1.000 21.586 0 321  TYR A CZ  1 ? 
ATOM   2368 O  OH  . TYR A  1 298 ? -10.253 -38.569 23.399  1.000 24.500 0 321  TYR A OH  1 ? 
ATOM   2369 N  N   . GLY A  1 299 ? -7.843  -34.562 17.738  1.000 23.977 0 322  GLY A N   1 ? 
ATOM   2370 C  CA  . GLY A  1 299 ? -8.876  -33.569 17.538  1.000 24.168 0 322  GLY A CA  1 ? 
ATOM   2371 C  C   . GLY A  1 299 ? -8.287  -32.344 16.855  1.000 20.067 0 322  GLY A C   1 ? 
ATOM   2372 O  O   . GLY A  1 299 ? -8.026  -32.366 15.667  1.000 20.428 0 322  GLY A O   1 ? 
ATOM   2373 N  N   . PHE A  1 300 ? -7.998  -31.288 17.622  1.000 19.785 0 323  PHE A N   1 ? 
ATOM   2374 C  CA  . PHE A  1 300 ? -7.650  -29.995 17.039  1.000 17.893 0 323  PHE A CA  1 ? 
ATOM   2375 C  C   . PHE A  1 300 ? -8.768  -29.528 16.098  1.000 17.696 0 323  PHE A C   1 ? 
ATOM   2376 O  O   . PHE A  1 300 ? -8.518  -28.936 15.062  1.000 19.456 0 323  PHE A O   1 ? 
ATOM   2377 C  CB  . PHE A  1 300 ? -6.263  -30.017 16.396  1.000 19.922 0 323  PHE A CB  1 ? 
ATOM   2378 C  CG  . PHE A  1 300 ? -5.131  -30.446 17.285  1.000 20.781 0 323  PHE A CG  1 ? 
ATOM   2379 C  CD1 . PHE A  1 300 ? -4.947  -31.786 17.633  1.000 21.713 0 323  PHE A CD1 1 ? 
ATOM   2380 C  CD2 . PHE A  1 300 ? -4.265  -29.515 17.830  1.000 20.436 0 323  PHE A CD2 1 ? 
ATOM   2381 C  CE1 . PHE A  1 300 ? -3.885  -32.166 18.446  1.000 21.491 0 323  PHE A CE1 1 ? 
ATOM   2382 C  CE2 . PHE A  1 300 ? -3.228  -29.887 18.650  1.000 19.405 0 323  PHE A CE2 1 ? 
ATOM   2383 C  CZ  . PHE A  1 300 ? -3.047  -31.226 18.976  1.000 21.659 0 323  PHE A CZ  1 ? 
ATOM   2384 N  N   . ARG A  1 301 ? -10.005 -29.829 16.472  1.000 17.971 0 324  ARG A N   1 ? 
ATOM   2385 C  CA  . ARG A  1 301 ? -11.182 -29.475 15.706  1.000 19.395 0 324  ARG A CA  1 ? 
ATOM   2386 C  C   . ARG A  1 301 ? -11.747 -28.116 16.108  1.000 19.575 0 324  ARG A C   1 ? 
ATOM   2387 O  O   . ARG A  1 301 ? -11.759 -27.767 17.290  1.000 17.730 0 324  ARG A O   1 ? 
ATOM   2388 C  CB  . ARG A  1 301 ? -12.231 -30.560 15.898  1.000 20.468 0 324  ARG A CB  1 ? 
ATOM   2389 C  CG  . ARG A  1 301 ? -11.775 -31.946 15.454  1.000 21.232 0 324  ARG A CG  1 ? 
ATOM   2390 C  CD  . ARG A  1 301 ? -12.973 -32.836 15.109  1.000 23.027 0 324  ARG A CD  1 ? 
ATOM   2391 N  NE  . ARG A  1 301 ? -13.632 -32.371 13.870  1.000 24.540 0 324  ARG A NE  1 ? 
ATOM   2392 C  CZ  . ARG A  1 301 ? -14.543 -33.060 13.200  1.000 26.178 0 324  ARG A CZ  1 ? 
ATOM   2393 N  NH1 . ARG A  1 301 ? -14.926 -34.249 13.634  1.000 26.078 0 324  ARG A NH1 1 ? 
ATOM   2394 N  NH2 . ARG A  1 301 ? -15.101 -32.543 12.121  1.000 25.278 0 324  ARG A NH2 1 ? 
ATOM   2395 N  N   . GLU A  1 302 ? -12.256 -27.381 15.109  1.000 19.637 0 325  GLU A N   1 ? 
ATOM   2396 C  CA  . GLU A  1 302 ? -13.035 -26.183 15.372  1.000 19.512 0 325  GLU A CA  1 ? 
ATOM   2397 C  C   . GLU A  1 302 ? -14.365 -26.531 16.007  1.000 22.941 0 325  GLU A C   1 ? 
ATOM   2398 O  O   . GLU A  1 302 ? -15.168 -27.293 15.447  1.000 22.996 0 325  GLU A O   1 ? 
ATOM   2399 C  CB  . GLU A  1 302 ? -13.461 -25.423 14.108  1.000 21.829 0 325  GLU A CB  1 ? 
ATOM   2400 C  CG  . GLU A  1 302 ? -12.361 -24.795 13.348  1.000 19.917 0 325  GLU A CG  1 ? 
ATOM   2401 C  CD  . GLU A  1 302 ? -12.686 -24.353 11.940  1.000 18.486 0 325  GLU A CD  1 ? 
ATOM   2402 O  OE1 . GLU A  1 302 ? -13.824 -24.614 11.431  1.000 20.481 0 325  GLU A OE1 1 ? 
ATOM   2403 O  OE2 . GLU A  1 302 ? -11.819 -23.717 11.346  1.000 19.725 0 325  GLU A OE2 1 ? 
ATOM   2404 N  N   . ILE A  1 303 ? -14.623 -25.886 17.140  1.000 20.217 0 326  ILE A N   1 ? 
ATOM   2405 C  CA  . ILE A  1 303 ? -15.878 -26.033 17.828  1.000 21.415 0 326  ILE A CA  1 ? 
ATOM   2406 C  C   . ILE A  1 303 ? -16.876 -25.177 17.071  1.000 24.804 0 326  ILE A C   1 ? 
ATOM   2407 O  O   . ILE A  1 303 ? -18.047 -25.546 16.994  1.000 23.585 0 326  ILE A O   1 ? 
ATOM   2408 C  CB  . ILE A  1 303 ? -15.771 -25.603 19.303  1.000 22.767 0 326  ILE A CB  1 ? 
ATOM   2409 C  CG1 . ILE A  1 303 ? -14.797 -26.469 20.105  1.000 25.273 0 326  ILE A CG1 1 ? 
ATOM   2410 C  CG2 . ILE A  1 303 ? -17.150 -25.589 19.961  1.000 24.293 0 326  ILE A CG2 1 ? 
ATOM   2411 C  CD1 . ILE A  1 303 ? -14.213 -25.746 21.286  1.000 28.260 0 326  ILE A CD1 1 ? 
ATOM   2412 N  N   . ILE A  1 304 ? -16.401 -24.024 16.565  1.000 21.342 0 327  ILE A N   1 ? 
ATOM   2413 C  CA  . ILE A  1 304 ? -17.290 -23.016 16.054  1.000 21.976 0 327  ILE A CA  1 ? 
ATOM   2414 C  C   . ILE A  1 304 ? -16.442 -21.971 15.356  1.000 21.385 0 327  ILE A C   1 ? 
ATOM   2415 O  O   . ILE A  1 304 ? -15.284 -21.754 15.753  1.000 20.010 0 327  ILE A O   1 ? 
ATOM   2416 C  CB  . ILE A  1 304 ? -18.143 -22.425 17.200  1.000 23.169 0 327  ILE A CB  1 ? 
ATOM   2417 C  CG1 . ILE A  1 304 ? -19.263 -21.535 16.679  1.000 25.078 0 327  ILE A CG1 1 ? 
ATOM   2418 C  CG2 . ILE A  1 304 ? -17.293 -21.729 18.245  1.000 23.120 0 327  ILE A CG2 1 ? 
ATOM   2419 C  CD1 . ILE A  1 304 ? -20.374 -21.318 17.668  1.000 27.870 0 327  ILE A CD1 1 ? 
ATOM   2420 N  N   . LEU A  1 305 ? -17.022 -21.360 14.320  1.000 18.223 0 328  LEU A N   1 ? 
ATOM   2421 C  CA  . LEU A  1 305 ? -16.488 -20.147 13.725  1.000 19.119 0 328  LEU A CA  1 ? 
ATOM   2422 C  C   . LEU A  1 305 ? -17.397 -18.978 14.083  1.000 21.057 0 328  LEU A C   1 ? 
ATOM   2423 O  O   . LEU A  1 305 ? -18.613 -19.125 14.203  1.000 19.723 0 328  LEU A O   1 ? 
ATOM   2424 C  CB  . LEU A  1 305 ? -16.413 -20.315 12.203  1.000 21.141 0 328  LEU A CB  1 ? 
ATOM   2425 C  CG  . LEU A  1 305 ? -15.489 -21.424 11.705  1.000 20.616 0 328  LEU A CG  1 ? 
ATOM   2426 C  CD1 . LEU A  1 305 ? -15.630 -21.590 10.205  1.000 23.135 0 328  LEU A CD1 1 ? 
ATOM   2427 C  CD2 . LEU A  1 305 ? -14.071 -21.123 12.096  1.000 18.976 0 328  LEU A CD2 1 ? 
ATOM   2428 N  N   . ASP A  1 306 ? -16.818 -17.790 14.173  1.000 20.315 0 329  ASP A N   1 ? 
ATOM   2429 C  CA  . ASP A  1 306 ? -17.603 -16.631 14.545  1.000 18.949 0 329  ASP A CA  1 ? 
ATOM   2430 C  C   . ASP A  1 306 ? -18.576 -16.248 13.420  1.000 20.377 0 329  ASP A C   1 ? 
ATOM   2431 O  O   . ASP A  1 306 ? -18.191 -16.004 12.273  1.000 19.967 0 329  ASP A O   1 ? 
ATOM   2432 C  CB  . ASP A  1 306 ? -16.716 -15.442 14.926  1.000 19.916 0 329  ASP A CB  1 ? 
ATOM   2433 C  CG  . ASP A  1 306 ? -17.549 -14.340 15.571  1.000 21.101 0 329  ASP A CG  1 ? 
ATOM   2434 O  OD1 . ASP A  1 306 ? -18.136 -13.515 14.819  1.000 21.684 0 329  ASP A OD1 1 ? 
ATOM   2435 O  OD2 . ASP A  1 306 ? -17.652 -14.367 16.817  1.000 21.015 0 329  ASP A OD2 1 ? 
ATOM   2436 N  N   . GLU A  1 307 ? -19.862 -16.126 13.771  1.000 20.759 0 330  GLU A N   1 ? 
ATOM   2437 C  CA  . GLU A  1 307 ? -20.933 -15.858 12.818  1.000 20.550 0 330  GLU A CA  1 ? 
ATOM   2438 C  C   . GLU A  1 307 ? -20.805 -14.527 12.092  1.000 20.705 0 330  GLU A C   1 ? 
ATOM   2439 O  O   . GLU A  1 307 ? -21.336 -14.366 10.982  1.000 23.082 0 330  GLU A O   1 ? 
ATOM   2440 C  CB  . GLU A  1 307 ? -22.259 -15.891 13.603  1.000 22.798 0 330  GLU A CB  1 ? 
ATOM   2441 C  CG  . GLU A  1 307 ? -22.498 -17.271 14.238  1.000 29.236 0 330  GLU A CG  1 ? 
ATOM   2442 C  CD  . GLU A  1 307 ? -22.058 -17.518 15.690  1.000 33.622 0 330  GLU A CD  1 ? 
ATOM   2443 O  OE1 . GLU A  1 307 ? -21.181 -16.771 16.172  1.000 26.250 0 330  GLU A OE1 1 ? 
ATOM   2444 O  OE2 . GLU A  1 307 ? -22.609 -18.483 16.355  1.000 33.524 0 330  GLU A OE2 1 ? 
ATOM   2445 N  N   . HIS A  1 308 ? -20.143 -13.567 12.738  1.000 18.306 0 331  HIS A N   1 ? 
ATOM   2446 C  CA  . HIS A  1 308 ? -20.001 -12.214 12.244  1.000 21.247 0 331  HIS A CA  1 ? 
ATOM   2447 C  C   . HIS A  1 308 ? -18.671 -11.995 11.520  1.000 21.587 0 331  HIS A C   1 ? 
ATOM   2448 O  O   . HIS A  1 308 ? -18.402 -10.888 11.056  1.000 21.691 0 331  HIS A O   1 ? 
ATOM   2449 C  CB  . HIS A  1 308 ? -20.101 -11.222 13.416  1.000 20.330 0 331  HIS A CB  1 ? 
ATOM   2450 C  CG  . HIS A  1 308 ? -21.414 -11.321 14.125  1.000 24.889 0 331  HIS A CG  1 ? 
ATOM   2451 N  ND1 . HIS A  1 308 ? -21.580 -11.828 15.404  1.000 32.485 0 331  HIS A ND1 1 ? 
ATOM   2452 C  CD2 . HIS A  1 308 ? -22.636 -11.030 13.698  1.000 30.684 0 331  HIS A CD2 1 ? 
ATOM   2453 C  CE1 . HIS A  1 308 ? -22.862 -11.828 15.736  1.000 26.667 0 331  HIS A CE1 1 ? 
ATOM   2454 N  NE2 . HIS A  1 308 ? -23.525 -11.376 14.708  1.000 34.626 0 331  HIS A NE2 1 ? 
ATOM   2455 N  N   . ARG A  1 309 ? -17.902 -13.065 11.315  1.000 18.695 0 332  ARG A N   1 ? 
ATOM   2456 C  CA  . ARG A  1 309 ? -16.520 -12.925 10.890  1.000 18.700 0 332  ARG A CA  1 ? 
ATOM   2457 C  C   . ARG A  1 309 ? -16.383 -12.180 9.555   1.000 19.469 0 332  ARG A C   1 ? 
ATOM   2458 O  O   . ARG A  1 309 ? -15.340 -11.570 9.329   1.000 19.470 0 332  ARG A O   1 ? 
ATOM   2459 C  CB  . ARG A  1 309 ? -15.851 -14.302 10.849  1.000 16.470 0 332  ARG A CB  1 ? 
ATOM   2460 C  CG  . ARG A  1 309 ? -16.385 -15.254 9.802   1.000 15.055 0 332  ARG A CG  1 ? 
ATOM   2461 C  CD  . ARG A  1 309 ? -15.821 -16.629 10.004  1.000 16.896 0 332  ARG A CD  1 ? 
ATOM   2462 N  NE  . ARG A  1 309 ? -16.365 -17.625 9.084   1.000 17.421 0 332  ARG A NE  1 ? 
ATOM   2463 C  CZ  . ARG A  1 309 ? -17.516 -18.293 9.244   1.000 19.902 0 332  ARG A CZ  1 ? 
ATOM   2464 N  NH1 . ARG A  1 309 ? -18.280 -18.083 10.304  1.000 18.757 0 332  ARG A NH1 1 ? 
ATOM   2465 N  NH2 . ARG A  1 309 ? -17.835 -19.254 8.385   1.000 19.861 0 332  ARG A NH2 1 ? 
ATOM   2466 N  N   . ASN A  1 310 ? -17.383 -12.274 8.652   1.000 17.953 0 333  ASN A N   1 ? 
ATOM   2467 C  CA  . ASN A  1 310 ? -17.269 -11.692 7.319   1.000 20.496 0 333  ASN A CA  1 ? 
ATOM   2468 C  C   . ASN A  1 310 ? -17.929 -10.307 7.215   1.000 22.009 0 333  ASN A C   1 ? 
ATOM   2469 O  O   . ASN A  1 310 ? -17.980 -9.730  6.120   1.000 24.187 0 333  ASN A O   1 ? 
ATOM   2470 C  CB  . ASN A  1 310 ? -17.929 -12.552 6.248   1.000 20.926 0 333  ASN A CB  1 ? 
ATOM   2471 C  CG  . ASN A  1 310 ? -17.266 -13.903 6.081   1.000 21.405 0 333  ASN A CG  1 ? 
ATOM   2472 O  OD1 . ASN A  1 310 ? -16.040 -14.000 6.033   1.000 21.298 0 333  ASN A OD1 1 ? 
ATOM   2473 N  ND2 . ASN A  1 310 ? -18.063 -14.943 6.000   1.000 21.852 0 333  ASN A ND2 1 ? 
ATOM   2474 N  N   . HIS A  1 311 ? -18.322 -9.746  8.353   1.000 23.488 0 334  HIS A N   1 ? 
ATOM   2475 C  CA  . HIS A  1 311 ? -19.251 -8.613  8.380   1.000 26.706 0 334  HIS A CA  1 ? 
ATOM   2476 C  C   . HIS A  1 311 ? -18.535 -7.260  8.330   1.000 24.475 0 334  HIS A C   1 ? 
ATOM   2477 O  O   . HIS A  1 311 ? -17.615 -6.996  9.105   1.000 21.454 0 334  HIS A O   1 ? 
ATOM   2478 C  CB  . HIS A  1 311 ? -20.173 -8.762  9.587   1.000 28.627 0 334  HIS A CB  1 ? 
ATOM   2479 C  CG  . HIS A  1 311 ? -21.227 -7.705  9.608   1.000 40.495 0 334  HIS A CG  1 ? 
ATOM   2480 N  ND1 . HIS A  1 311 ? -21.923 -7.369  8.463   1.000 44.629 0 334  HIS A ND1 1 ? 
ATOM   2481 C  CD2 . HIS A  1 311 ? -21.677 -6.889  10.582  1.000 45.438 0 334  HIS A CD2 1 ? 
ATOM   2482 C  CE1 . HIS A  1 311 ? -22.779 -6.396  8.748   1.000 44.791 0 334  HIS A CE1 1 ? 
ATOM   2483 N  NE2 . HIS A  1 311 ? -22.644 -6.091  10.028  1.000 44.819 0 334  HIS A NE2 1 ? 
ATOM   2484 N  N   . PRO A  1 312 ? -18.907 -6.342  7.399   1.000 25.124 0 335  PRO A N   1 ? 
ATOM   2485 C  CA  . PRO A  1 312 ? -18.336 -4.997  7.360   1.000 24.779 0 335  PRO A CA  1 ? 
ATOM   2486 C  C   . PRO A  1 312 ? -18.707 -4.094  8.536   1.000 21.156 0 335  PRO A C   1 ? 
ATOM   2487 O  O   . PRO A  1 312 ? -18.105 -3.033  8.657   1.000 23.854 0 335  PRO A O   1 ? 
ATOM   2488 C  CB  . PRO A  1 312 ? -18.823 -4.417  6.012   1.000 27.784 0 335  PRO A CB  1 ? 
ATOM   2489 C  CG  . PRO A  1 312 ? -20.066 -5.213  5.680   1.000 30.470 0 335  PRO A CG  1 ? 
ATOM   2490 C  CD  . PRO A  1 312 ? -19.800 -6.593  6.246   1.000 29.874 0 335  PRO A CD  1 ? 
ATOM   2491 N  N   . GLY A  1 313 ? -19.637 -4.544  9.391   1.000 20.723 0 336  GLY A N   1 ? 
ATOM   2492 C  CA  . GLY A  1 313 ? -19.999 -3.885  10.632  1.000 23.224 0 336  GLY A CA  1 ? 
ATOM   2493 C  C   . GLY A  1 313 ? -19.574 -4.650  11.881  1.000 22.798 0 336  GLY A C   1 ? 
ATOM   2494 O  O   . GLY A  1 313 ? -20.062 -4.355  12.953  1.000 24.567 0 336  GLY A O   1 ? 
ATOM   2495 N  N   . TYR A  1 314 ? -18.596 -5.571  11.753  1.000 22.930 0 337  TYR A N   1 ? 
ATOM   2496 C  CA  . TYR A  1 314 ? -18.136 -6.413  12.854  1.000 22.037 0 337  TYR A CA  1 ? 
ATOM   2497 C  C   . TYR A  1 314 ? -17.839 -5.627  14.126  1.000 24.626 0 337  TYR A C   1 ? 
ATOM   2498 O  O   . TYR A  1 314 ? -18.225 -6.047  15.216  1.000 25.075 0 337  TYR A O   1 ? 
ATOM   2499 C  CB  . TYR A  1 314 ? -16.866 -7.116  12.385  1.000 22.247 0 337  TYR A CB  1 ? 
ATOM   2500 C  CG  . TYR A  1 314 ? -16.231 -8.095  13.356  1.000 19.899 0 337  TYR A CG  1 ? 
ATOM   2501 C  CD1 . TYR A  1 314 ? -16.571 -9.443  13.295  1.000 21.300 0 337  TYR A CD1 1 ? 
ATOM   2502 C  CD2 . TYR A  1 314 ? -15.215 -7.714  14.224  1.000 19.959 0 337  TYR A CD2 1 ? 
ATOM   2503 C  CE1 . TYR A  1 314 ? -16.002 -10.379 14.146  1.000 19.246 0 337  TYR A CE1 1 ? 
ATOM   2504 C  CE2 . TYR A  1 314 ? -14.619 -8.653  15.083  1.000 19.524 0 337  TYR A CE2 1 ? 
ATOM   2505 C  CZ  . TYR A  1 314 ? -14.959 -9.998  14.985  1.000 21.144 0 337  TYR A CZ  1 ? 
ATOM   2506 O  OH  . TYR A  1 314 ? -14.386 -10.975 15.789  1.000 20.054 0 337  TYR A OH  1 ? 
ATOM   2507 N  N   . ALA A  1 315 ? -17.133 -4.513  14.001  1.000 24.831 0 338  ALA A N   1 ? 
ATOM   2508 C  CA  . ALA A  1 315 ? -16.758 -3.761  15.190  1.000 34.996 0 338  ALA A CA  1 ? 
ATOM   2509 C  C   . ALA A  1 315 ? -17.590 -2.502  15.381  1.000 37.671 0 338  ALA A C   1 ? 
ATOM   2510 O  O   . ALA A  1 315 ? -17.348 -1.782  16.333  1.000 51.587 0 338  ALA A O   1 ? 
ATOM   2511 C  CB  . ALA A  1 315 ? -15.318 -3.396  15.088  1.000 37.121 0 338  ALA A CB  1 ? 
ATOM   2512 N  N   . THR A  1 316 ? -18.559 -2.256  14.502  1.000 46.335 0 339  THR A N   1 ? 
ATOM   2513 C  CA  . THR A  1 316 ? -19.167 -0.936  14.340  1.000 52.698 0 339  THR A CA  1 ? 
ATOM   2514 C  C   . THR A  1 316 ? -19.841 -0.536  15.649  1.000 57.391 0 339  THR A C   1 ? 
ATOM   2515 O  O   . THR A  1 316 ? -19.688 0.607   16.091  1.000 61.085 0 339  THR A O   1 ? 
ATOM   2516 C  CB  . THR A  1 316 ? -20.077 -0.900  13.095  1.000 53.897 0 339  THR A CB  1 ? 
ATOM   2517 O  OG1 . THR A  1 316 ? -19.175 -0.950  11.989  1.000 49.798 0 339  THR A OG1 1 ? 
ATOM   2518 C  CG2 . THR A  1 316 ? -20.955 0.332   12.956  1.000 55.725 0 339  THR A CG2 1 ? 
ATOM   2519 N  N   . LEU A  1 317 ? -20.556 -1.487  16.265  1.000 56.278 0 340  LEU A N   1 ? 
ATOM   2520 C  CA  . LEU A  1 317 ? -21.216 -1.234  17.535  1.000 65.781 0 340  LEU A CA  1 ? 
ATOM   2521 C  C   . LEU A  1 317 ? -20.250 -1.583  18.668  1.000 69.172 0 340  LEU A C   1 ? 
ATOM   2522 O  O   . LEU A  1 317 ? -19.384 -2.437  18.468  1.000 65.006 0 340  LEU A O   1 ? 
ATOM   2523 C  CB  . LEU A  1 317 ? -22.509 -2.063  17.607  1.000 67.424 0 340  LEU A CB  1 ? 
ATOM   2524 C  CG  . LEU A  1 317 ? -23.701 -1.568  16.776  1.000 74.519 0 340  LEU A CG  1 ? 
ATOM   2525 C  CD1 . LEU A  1 317 ? -25.003 -2.101  17.357  1.000 78.281 0 340  LEU A CD1 1 ? 
ATOM   2526 C  CD2 . LEU A  1 317 ? -23.766 -0.041  16.674  1.000 71.849 0 340  LEU A CD2 1 ? 
ATOM   2527 N  N   . ASP A  1 318 ? -20.402 -0.913  19.833  1.000 63.699 0 341  ASP A N   1 ? 
ATOM   2528 C  CA  . ASP A  1 318 ? -19.661 -1.236  21.054  1.000 61.837 0 341  ASP A CA  1 ? 
ATOM   2529 C  C   . ASP A  1 318 ? -18.157 -1.286  20.792  1.000 58.681 0 341  ASP A C   1 ? 
ATOM   2530 O  O   . ASP A  1 318 ? -17.477 -2.172  21.311  1.000 56.106 0 341  ASP A O   1 ? 
ATOM   2531 C  CB  . ASP A  1 318 ? -20.122 -2.578  21.632  1.000 58.856 0 341  ASP A CB  1 ? 
ATOM   2532 C  CG  . ASP A  1 318 ? -21.587 -2.534  22.009  1.000 56.521 0 341  ASP A CG  1 ? 
ATOM   2533 O  OD1 . ASP A  1 318 ? -22.064 -1.423  22.223  1.000 57.625 0 341  ASP A OD1 1 ? 
ATOM   2534 O  OD2 . ASP A  1 318 ? -22.239 -3.590  22.034  1.000 52.517 0 341  ASP A OD2 1 ? 
ATOM   2535 N  N   . GLY A  1 319 ? -17.669 -0.311  20.000  1.000 63.104 0 342  GLY A N   1 ? 
ATOM   2536 C  CA  . GLY A  1 319 ? -16.288 -0.220  19.533  1.000 64.697 0 342  GLY A CA  1 ? 
ATOM   2537 C  C   . GLY A  1 319 ? -15.232 -0.622  20.569  1.000 59.967 0 342  GLY A C   1 ? 
ATOM   2538 O  O   . GLY A  1 319 ? -14.279 -1.331  20.245  1.000 53.937 0 342  GLY A O   1 ? 
ATOM   2539 N  N   . PRO A  1 320 ? -15.323 -0.172  21.842  1.000 75.299 0 343  PRO A N   1 ? 
ATOM   2540 C  CA  . PRO A  1 320 ? -14.317 -0.566  22.839  1.000 84.230 0 343  PRO A CA  1 ? 
ATOM   2541 C  C   . PRO A  1 320 ? -14.365 -1.996  23.404  1.000 70.327 0 343  PRO A C   1 ? 
ATOM   2542 O  O   . PRO A  1 320 ? -13.459 -2.387  24.146  1.000 76.749 0 343  PRO A O   1 ? 
ATOM   2543 C  CB  . PRO A  1 320 ? -14.511 0.484   23.955  1.000 91.988 0 343  PRO A CB  1 ? 
ATOM   2544 C  CG  . PRO A  1 320 ? -15.964 0.938   23.823  1.000 91.790 0 343  PRO A CG  1 ? 
ATOM   2545 C  CD  . PRO A  1 320 ? -16.304 0.807   22.352  1.000 80.541 0 343  PRO A CD  1 ? 
ATOM   2546 N  N   . GLU A  1 321 ? -15.372 -2.805  23.048  1.000 48.668 0 344  GLU A N   1 ? 
ATOM   2547 C  CA  . GLU A  1 321 ? -15.542 -4.072  23.741  1.000 43.658 0 344  GLU A CA  1 ? 
ATOM   2548 C  C   . GLU A  1 321 ? -14.965 -5.217  22.912  1.000 39.455 0 344  GLU A C   1 ? 
ATOM   2549 O  O   . GLU A  1 321 ? -15.299 -5.318  21.738  1.000 45.448 0 344  GLU A O   1 ? 
ATOM   2550 C  CB  . GLU A  1 321 ? -17.021 -4.282  24.009  1.000 50.893 0 344  GLU A CB  1 ? 
ATOM   2551 C  CG  . GLU A  1 321 ? -17.668 -3.021  24.507  1.000 58.576 0 344  GLU A CG  1 ? 
ATOM   2552 C  CD  . GLU A  1 321 ? -18.835 -3.313  25.413  1.000 72.757 0 344  GLU A CD  1 ? 
ATOM   2553 O  OE1 . GLU A  1 321 ? -19.932 -3.575  24.880  1.000 86.729 0 344  GLU A OE1 1 ? 
ATOM   2554 O  OE2 . GLU A  1 321 ? -18.618 -3.332  26.641  1.000 85.585 0 344  GLU A OE2 1 ? 
ATOM   2555 N  N   . ASP A  1 322 ? -14.136 -6.077  23.547  1.000 31.016 0 345  ASP A N   1 ? 
ATOM   2556 C  CA  . ASP A  1 322 ? -13.591 -7.272  22.915  1.000 30.059 0 345  ASP A CA  1 ? 
ATOM   2557 C  C   . ASP A  1 322 ? -14.712 -8.189  22.444  1.000 25.907 0 345  ASP A C   1 ? 
ATOM   2558 O  O   . ASP A  1 322 ? -15.700 -8.376  23.147  1.000 24.292 0 345  ASP A O   1 ? 
ATOM   2559 C  CB  . ASP A  1 322 ? -12.732 -8.035  23.913  1.000 29.727 0 345  ASP A CB  1 ? 
ATOM   2560 C  CG  . ASP A  1 322 ? -11.357 -7.405  24.028  1.000 40.867 0 345  ASP A CG  1 ? 
ATOM   2561 O  OD1 . ASP A  1 322 ? -11.089 -6.462  23.229  1.000 48.700 0 345  ASP A OD1 1 ? 
ATOM   2562 O  OD2 . ASP A  1 322 ? -10.562 -7.894  24.851  1.000 38.799 0 345  ASP A OD2 1 ? 
ATOM   2563 N  N   . ARG A  1 323 ? -14.505 -8.822  21.289  1.000 22.446 0 346  ARG A N   1 ? 
ATOM   2564 C  CA  . ARG A  1 323 ? -15.491 -9.678  20.704  1.000 22.263 0 346  ARG A CA  1 ? 
ATOM   2565 C  C   . ARG A  1 323 ? -14.797 -10.854 20.024  1.000 20.123 0 346  ARG A C   1 ? 
ATOM   2566 O  O   . ARG A  1 323 ? -13.593 -10.805 19.722  1.000 20.308 0 346  ARG A O   1 ? 
ATOM   2567 C  CB  . ARG A  1 323 ? -16.362 -8.884  19.727  1.000 25.904 0 346  ARG A CB  1 ? 
ATOM   2568 C  CG  . ARG A  1 323 ? -15.640 -8.445  18.461  1.000 29.123 0 346  ARG A CG  1 ? 
ATOM   2569 C  CD  . ARG A  1 323 ? -16.470 -7.366  17.755  1.000 30.416 0 346  ARG A CD  1 ? 
ATOM   2570 N  NE  . ARG A  1 323 ? -16.472 -6.173  18.597  1.000 33.432 0 346  ARG A NE  1 ? 
ATOM   2571 C  CZ  . ARG A  1 323 ? -17.530 -5.409  18.842  1.000 38.138 0 346  ARG A CZ  1 ? 
ATOM   2572 N  NH1 . ARG A  1 323 ? -18.697 -5.660  18.263  1.000 40.168 0 346  ARG A NH1 1 ? 
ATOM   2573 N  NH2 . ARG A  1 323 ? -17.400 -4.397  19.681  1.000 42.078 0 346  ARG A NH2 1 ? 
ATOM   2574 N  N   . GLY A  1 324 ? -15.585 -11.896 19.817  1.000 19.047 0 347  GLY A N   1 ? 
ATOM   2575 C  CA  . GLY A  1 324 ? -15.155 -13.055 19.050  1.000 19.532 0 347  GLY A CA  1 ? 
ATOM   2576 C  C   . GLY A  1 324 ? -15.379 -14.311 19.885  1.000 19.824 0 347  GLY A C   1 ? 
ATOM   2577 O  O   . GLY A  1 324 ? -16.276 -14.330 20.746  1.000 19.394 0 347  GLY A O   1 ? 
ATOM   2578 N  N   . LYS A  1 325 ? -14.553 -15.324 19.622  1.000 18.917 0 348  LYS A N   1 ? 
ATOM   2579 C  CA  . LYS A  1 325 ? -14.705 -16.665 20.164  1.000 18.963 0 348  LYS A CA  1 ? 
ATOM   2580 C  C   . LYS A  1 325 ? -13.562 -17.074 21.103  1.000 19.171 0 348  LYS A C   1 ? 
ATOM   2581 O  O   . LYS A  1 325 ? -13.490 -18.257 21.489  1.000 19.629 0 348  LYS A O   1 ? 
ATOM   2582 C  CB  . LYS A  1 325 ? -14.832 -17.624 18.964  1.000 18.904 0 348  LYS A CB  1 ? 
ATOM   2583 C  CG  . LYS A  1 325 ? -16.139 -17.554 18.181  1.000 21.502 0 348  LYS A CG  1 ? 
ATOM   2584 C  CD  . LYS A  1 325 ? -17.357 -17.845 19.005  1.000 20.748 0 348  LYS A CD  1 ? 
ATOM   2585 C  CE  . LYS A  1 325 ? -18.657 -17.847 18.223  1.000 22.516 0 348  LYS A CE  1 ? 
ATOM   2586 N  NZ  . LYS A  1 325 ? -19.120 -16.478 17.916  1.000 23.768 0 348  LYS A NZ  1 ? 
ATOM   2587 N  N   . ALA A  1 326 ? -12.735 -16.113 21.560  1.000 20.065 0 349  ALA A N   1 ? 
ATOM   2588 C  CA  . ALA A  1 326 ? -11.719 -16.396 22.570  1.000 21.177 0 349  ALA A CA  1 ? 
ATOM   2589 C  C   . ALA A  1 326 ? -12.347 -16.543 23.961  1.000 18.984 0 349  ALA A C   1 ? 
ATOM   2590 O  O   . ALA A  1 326 ? -13.451 -16.035 24.208  1.000 19.533 0 349  ALA A O   1 ? 
ATOM   2591 C  CB  . ALA A  1 326 ? -10.650 -15.339 22.574  1.000 22.698 0 349  ALA A CB  1 ? 
ATOM   2592 N  N   . TYR A  1 327 ? -11.618 -17.263 24.827  1.000 18.963 0 350  TYR A N   1 ? 
ATOM   2593 C  CA  . TYR A  1 327 ? -11.911 -17.613 26.212  1.000 18.902 0 350  TYR A CA  1 ? 
ATOM   2594 C  C   . TYR A  1 327 ? -12.903 -18.771 26.252  1.000 19.156 0 350  TYR A C   1 ? 
ATOM   2595 O  O   . TYR A  1 327 ? -13.845 -18.829 25.451  1.000 17.120 0 350  TYR A O   1 ? 
ATOM   2596 C  CB  . TYR A  1 327 ? -12.512 -16.489 27.062  1.000 21.966 0 350  TYR A CB  1 ? 
ATOM   2597 C  CG  . TYR A  1 327 ? -11.678 -15.773 28.112  1.000 22.683 0 350  TYR A CG  1 ? 
ATOM   2598 C  CD1 . TYR A  1 327 ? -10.748 -16.427 28.907  1.000 24.532 0 350  TYR A CD1 1 ? 
ATOM   2599 C  CD2 . TYR A  1 327 ? -11.951 -14.428 28.402  1.000 24.688 0 350  TYR A CD2 1 ? 
ATOM   2600 C  CE1 . TYR A  1 327 ? -10.061 -15.753 29.920  1.000 26.446 0 350  TYR A CE1 1 ? 
ATOM   2601 C  CE2 . TYR A  1 327 ? -11.285 -13.754 29.418  1.000 29.322 0 350  TYR A CE2 1 ? 
ATOM   2602 C  CZ  . TYR A  1 327 ? -10.312 -14.408 30.160  1.000 27.176 0 350  TYR A CZ  1 ? 
ATOM   2603 O  OH  . TYR A  1 327 ? -9.656  -13.673 31.124  1.000 25.566 0 350  TYR A OH  1 ? 
ATOM   2604 N  N   . SER A  1 328 ? -12.727 -19.685 27.219  1.000 17.512 0 351  SER A N   1 ? 
ATOM   2605 C  CA  . SER A  1 328 ? -13.694 -20.750 27.371  1.000 17.626 0 351  SER A CA  1 ? 
ATOM   2606 C  C   . SER A  1 328 ? -13.650 -21.322 28.783  1.000 16.991 0 351  SER A C   1 ? 
ATOM   2607 O  O   . SER A  1 328 ? -12.669 -21.158 29.497  1.000 18.714 0 351  SER A O   1 ? 
ATOM   2608 C  CB  . SER A  1 328 ? -13.436 -21.826 26.373  1.000 17.555 0 351  SER A CB  1 ? 
ATOM   2609 O  OG  . SER A  1 328 ? -12.129 -22.364 26.584  1.000 21.818 0 351  SER A OG  1 ? 
ATOM   2610 N  N   . GLU A  1 329 ? -14.735 -22.010 29.155  1.000 18.307 0 352  GLU A N   1 ? 
ATOM   2611 C  CA  . GLU A  1 329 ? -14.832 -22.758 30.394  1.000 19.027 0 352  GLU A CA  1 ? 
ATOM   2612 C  C   . GLU A  1 329 ? -15.689 -23.985 30.062  1.000 21.148 0 352  GLU A C   1 ? 
ATOM   2613 O  O   . GLU A  1 329 ? -16.559 -23.893 29.198  1.000 20.644 0 352  GLU A O   1 ? 
ATOM   2614 C  CB  . GLU A  1 329 ? -15.468 -21.886 31.497  1.000 20.313 0 352  GLU A CB  1 ? 
ATOM   2615 C  CG  . GLU A  1 329 ? -15.296 -22.434 32.900  1.000 23.068 0 352  GLU A CG  1 ? 
ATOM   2616 C  CD  . GLU A  1 329 ? -15.740 -21.520 34.061  1.000 27.003 0 352  GLU A CD  1 ? 
ATOM   2617 O  OE1 . GLU A  1 329 ? -16.515 -20.521 33.833  1.000 24.971 0 352  GLU A OE1 1 ? 
ATOM   2618 O  OE2 . GLU A  1 329 ? -15.310 -21.789 35.197  1.000 29.543 0 352  GLU A OE2 1 ? 
ATOM   2619 N  N   A MET A  1 330 ? -15.470 -25.114 30.744  0.500 20.292 0 353  MET A N   1 ? 
ATOM   2620 N  N   B MET A  1 330 ? -15.457 -25.122 30.731  0.500 19.808 0 353  MET A N   1 ? 
ATOM   2621 C  CA  A MET A  1 330 ? -16.164 -26.337 30.353  0.500 22.153 0 353  MET A CA  1 ? 
ATOM   2622 C  CA  B MET A  1 330 ? -16.164 -26.343 30.352  0.500 21.236 0 353  MET A CA  1 ? 
ATOM   2623 C  C   A MET A  1 330 ? -16.738 -27.076 31.553  0.500 22.298 0 353  MET A C   1 ? 
ATOM   2624 C  C   B MET A  1 330 ? -16.752 -27.058 31.559  0.500 21.834 0 353  MET A C   1 ? 
ATOM   2625 O  O   A MET A  1 330 ? -16.169 -27.030 32.641  0.500 22.264 0 353  MET A O   1 ? 
ATOM   2626 O  O   B MET A  1 330 ? -16.205 -26.978 32.655  0.500 22.013 0 353  MET A O   1 ? 
ATOM   2627 C  CB  A MET A  1 330 ? -15.233 -27.306 29.620  0.500 23.957 0 353  MET A CB  1 ? 
ATOM   2628 C  CB  B MET A  1 330 ? -15.252 -27.344 29.636  0.500 22.140 0 353  MET A CB  1 ? 
ATOM   2629 C  CG  A MET A  1 330 ? -14.032 -27.733 30.438  0.500 28.237 0 353  MET A CG  1 ? 
ATOM   2630 C  CG  B MET A  1 330 ? -14.252 -28.031 30.547  0.500 25.586 0 353  MET A CG  1 ? 
ATOM   2631 S  SD  A MET A  1 330 ? -13.122 -29.091 29.644  0.500 35.147 0 353  MET A SD  1 ? 
ATOM   2632 S  SD  B MET A  1 330 ? -13.022 -28.984 29.607  0.500 29.533 0 353  MET A SD  1 ? 
ATOM   2633 C  CE  A MET A  1 330 ? -13.629 -30.474 30.663  0.500 31.556 0 353  MET A CE  1 ? 
ATOM   2634 C  CE  B MET A  1 330 ? -11.691 -27.784 29.524  0.500 26.099 0 353  MET A CE  1 ? 
ATOM   2635 N  N   . VAL A  1 331 ? -17.842 -27.803 31.311  1.000 20.956 0 354  VAL A N   1 ? 
ATOM   2636 C  CA  . VAL A  1 331 ? -18.442 -28.685 32.306  1.000 24.085 0 354  VAL A CA  1 ? 
ATOM   2637 C  C   . VAL A  1 331 ? -18.837 -29.959 31.570  1.000 24.207 0 354  VAL A C   1 ? 
ATOM   2638 O  O   . VAL A  1 331 ? -19.600 -29.874 30.600  1.000 24.879 0 354  VAL A O   1 ? 
ATOM   2639 C  CB  . VAL A  1 331 ? -19.678 -28.047 32.968  1.000 26.119 0 354  VAL A CB  1 ? 
ATOM   2640 C  CG1 . VAL A  1 331 ? -20.551 -29.070 33.697  1.000 28.256 0 354  VAL A CG1 1 ? 
ATOM   2641 C  CG2 . VAL A  1 331 ? -19.297 -26.924 33.929  1.000 28.509 0 354  VAL A CG2 1 ? 
ATOM   2642 N  N   . GLN A  1 332 ? -18.390 -31.103 32.083  1.000 21.680 0 355  GLN A N   1 ? 
ATOM   2643 C  CA  . GLN A  1 332 ? -18.768 -32.379 31.480  1.000 23.564 0 355  GLN A CA  1 ? 
ATOM   2644 C  C   . GLN A  1 332 ? -20.267 -32.605 31.702  1.000 22.349 0 355  GLN A C   1 ? 
ATOM   2645 O  O   . GLN A  1 332 ? -20.736 -32.333 32.805  1.000 26.231 0 355  GLN A O   1 ? 
ATOM   2646 C  CB  . GLN A  1 332 ? -17.925 -33.508 32.062  1.000 25.317 0 355  GLN A CB  1 ? 
ATOM   2647 C  CG  . GLN A  1 332 ? -18.265 -34.826 31.369  1.000 24.717 0 355  GLN A CG  1 ? 
ATOM   2648 C  CD  . GLN A  1 332 ? -17.306 -35.921 31.739  1.000 24.719 0 355  GLN A CD  1 ? 
ATOM   2649 O  OE1 . GLN A  1 332 ? -16.505 -35.779 32.664  1.000 23.385 0 355  GLN A OE1 1 ? 
ATOM   2650 N  NE2 . GLN A  1 332 ? -17.344 -36.997 30.962  1.000 27.732 0 355  GLN A NE2 1 ? 
ATOM   2651 N  N   . LEU A  1 333 ? -21.029 -33.074 30.690  1.000 22.883 0 356  LEU A N   1 ? 
ATOM   2652 C  CA  . LEU A  1 333 ? -22.460 -33.313 30.883  1.000 23.477 0 356  LEU A CA  1 ? 
ATOM   2653 C  C   . LEU A  1 333 ? -22.771 -34.798 31.096  1.000 29.530 0 356  LEU A C   1 ? 
ATOM   2654 O  O   . LEU A  1 333 ? -23.686 -35.116 31.867  1.000 29.130 0 356  LEU A O   1 ? 
ATOM   2655 C  CB  . LEU A  1 333 ? -23.290 -32.827 29.691  1.000 24.546 0 356  LEU A CB  1 ? 
ATOM   2656 C  CG  . LEU A  1 333 ? -23.217 -31.341 29.389  1.000 24.671 0 356  LEU A CG  1 ? 
ATOM   2657 C  CD1 . LEU A  1 333 ? -24.109 -30.996 28.224  1.000 25.863 0 356  LEU A CD1 1 ? 
ATOM   2658 C  CD2 . LEU A  1 333 ? -23.593 -30.541 30.616  1.000 28.114 0 356  LEU A CD2 1 ? 
ATOM   2659 N  N   . ASP A  1 334 ? -22.070 -35.682 30.380  1.000 29.750 0 357  ASP A N   1 ? 
ATOM   2660 C  CA  . ASP A  1 334 ? -22.241 -37.118 30.572  1.000 30.704 0 357  ASP A CA  1 ? 
ATOM   2661 C  C   . ASP A  1 334 ? -20.999 -37.760 29.989  1.000 29.906 0 357  ASP A C   1 ? 
ATOM   2662 O  O   . ASP A  1 334 ? -20.016 -37.062 29.724  1.000 28.455 0 357  ASP A O   1 ? 
ATOM   2663 C  CB  . ASP A  1 334 ? -23.573 -37.597 29.969  1.000 31.134 0 357  ASP A CB  1 ? 
ATOM   2664 C  CG  . ASP A  1 334 ? -23.693 -37.416 28.468  1.000 32.587 0 357  ASP A CG  1 ? 
ATOM   2665 O  OD1 . ASP A  1 334 ? -22.662 -37.394 27.770  1.000 35.051 0 357  ASP A OD1 1 ? 
ATOM   2666 O  OD2 . ASP A  1 334 ? -24.820 -37.257 28.003  1.000 35.217 0 357  ASP A OD2 1 ? 
ATOM   2667 N  N   . LYS A  1 335 ? -21.033 -39.068 29.747  1.000 29.500 0 358  LYS A N   1 ? 
ATOM   2668 C  CA  . LYS A  1 335 ? -19.833 -39.741 29.283  1.000 30.370 0 358  LYS A CA  1 ? 
ATOM   2669 C  C   . LYS A  1 335 ? -19.282 -39.121 27.987  1.000 26.770 0 358  LYS A C   1 ? 
ATOM   2670 O  O   . LYS A  1 335 ? -18.080 -39.152 27.739  1.000 28.511 0 358  LYS A O   1 ? 
ATOM   2671 C  CB  . LYS A  1 335 ? -20.179 -41.216 29.058  1.000 38.066 0 358  LYS A CB  1 ? 
ATOM   2672 C  CG  . LYS A  1 335 ? -18.988 -42.122 28.804  1.000 51.436 0 358  LYS A CG  1 ? 
ATOM   2673 C  CD  . LYS A  1 335 ? -19.330 -43.581 29.074  1.000 65.608 0 358  LYS A CD  1 ? 
ATOM   2674 C  CE  . LYS A  1 335 ? -18.110 -44.475 29.160  1.000 76.759 0 358  LYS A CE  1 ? 
ATOM   2675 N  NZ  . LYS A  1 335 ? -17.491 -44.690 27.829  1.000 79.283 0 358  LYS A NZ  1 ? 
ATOM   2676 N  N   . ASN A  1 336 ? -20.152 -38.644 27.109  1.000 25.615 0 359  ASN A N   1 ? 
ATOM   2677 C  CA  . ASN A  1 336 ? -19.704 -38.248 25.780  1.000 29.781 0 359  ASN A CA  1 ? 
ATOM   2678 C  C   . ASN A  1 336 ? -19.720 -36.736 25.561  1.000 27.412 0 359  ASN A C   1 ? 
ATOM   2679 O  O   . ASN A  1 336 ? -19.065 -36.252 24.651  1.000 27.950 0 359  ASN A O   1 ? 
ATOM   2680 C  CB  . ASN A  1 336 ? -20.548 -38.890 24.691  1.000 28.814 0 359  ASN A CB  1 ? 
ATOM   2681 C  CG  . ASN A  1 336 ? -20.204 -40.354 24.501  1.000 32.605 0 359  ASN A CG  1 ? 
ATOM   2682 O  OD1 . ASN A  1 336 ? -19.042 -40.757 24.420  1.000 34.227 0 359  ASN A OD1 1 ? 
ATOM   2683 N  ND2 . ASN A  1 336 ? -21.232 -41.163 24.486  1.000 38.587 0 359  ASN A ND2 1 ? 
ATOM   2684 N  N   . ARG A  1 337 ? -20.482 -36.004 26.362  1.000 27.918 0 360  ARG A N   1 ? 
ATOM   2685 C  CA  . ARG A  1 337 ? -20.825 -34.631 26.006  1.000 24.285 0 360  ARG A CA  1 ? 
ATOM   2686 C  C   . ARG A  1 337 ? -20.233 -33.662 27.023  1.000 26.211 0 360  ARG A C   1 ? 
ATOM   2687 O  O   . ARG A  1 337 ? -20.203 -33.913 28.235  1.000 23.916 0 360  ARG A O   1 ? 
ATOM   2688 C  CB  . ARG A  1 337 ? -22.339 -34.474 25.903  1.000 26.646 0 360  ARG A CB  1 ? 
ATOM   2689 C  CG  . ARG A  1 337 ? -22.989 -35.351 24.837  1.000 30.335 0 360  ARG A CG  1 ? 
ATOM   2690 C  CD  . ARG A  1 337 ? -24.355 -35.818 25.323  1.000 35.486 0 360  ARG A CD  1 ? 
ATOM   2691 N  NE  . ARG A  1 337 ? -25.252 -34.707 25.283  1.000 36.162 0 360  ARG A NE  1 ? 
ATOM   2692 C  CZ  . ARG A  1 337 ? -25.915 -34.186 26.301  1.000 32.351 0 360  ARG A CZ  1 ? 
ATOM   2693 N  NH1 . ARG A  1 337 ? -25.987 -34.779 27.474  1.000 35.065 0 360  ARG A NH1 1 ? 
ATOM   2694 N  NH2 . ARG A  1 337 ? -26.540 -33.042 26.096  1.000 31.468 0 360  ARG A NH2 1 ? 
ATOM   2695 N  N   . ILE A  1 338 ? -19.782 -32.533 26.478  1.000 23.921 0 361  ILE A N   1 ? 
ATOM   2696 C  CA  . ILE A  1 338 ? -19.155 -31.471 27.244  1.000 24.737 0 361  ILE A CA  1 ? 
ATOM   2697 C  C   . ILE A  1 338 ? -19.856 -30.171 26.872  1.000 22.211 0 361  ILE A C   1 ? 
ATOM   2698 O  O   . ILE A  1 338 ? -19.951 -29.855 25.687  1.000 22.508 0 361  ILE A O   1 ? 
ATOM   2699 C  CB  . ILE A  1 338 ? -17.652 -31.376 26.926  1.000 25.964 0 361  ILE A CB  1 ? 
ATOM   2700 C  CG1 . ILE A  1 338 ? -16.934 -32.718 27.066  1.000 27.105 0 361  ILE A CG1 1 ? 
ATOM   2701 C  CG2 . ILE A  1 338 ? -16.988 -30.305 27.784  1.000 26.179 0 361  ILE A CG2 1 ? 
ATOM   2702 C  CD1 . ILE A  1 338 ? -15.517 -32.665 26.576  1.000 29.097 0 361  ILE A CD1 1 ? 
ATOM   2703 N  N   . LEU A  1 339 ? -20.234 -29.401 27.894  1.000 22.489 0 362  LEU A N   1 ? 
ATOM   2704 C  CA  . LEU A  1 339 ? -20.756 -28.053 27.734  1.000 22.173 0 362  LEU A CA  1 ? 
ATOM   2705 C  C   . LEU A  1 339 ? -19.588 -27.067 27.825  1.000 20.569 0 362  LEU A C   1 ? 
ATOM   2706 O  O   . LEU A  1 339 ? -18.812 -27.120 28.760  1.000 20.636 0 362  LEU A O   1 ? 
ATOM   2707 C  CB  . LEU A  1 339 ? -21.786 -27.803 28.828  1.000 22.379 0 362  LEU A CB  1 ? 
ATOM   2708 C  CG  . LEU A  1 339 ? -22.337 -26.379 28.917  1.000 23.152 0 362  LEU A CG  1 ? 
ATOM   2709 C  CD1 . LEU A  1 339 ? -23.216 -26.056 27.729  1.000 22.977 0 362  LEU A CD1 1 ? 
ATOM   2710 C  CD2 . LEU A  1 339 ? -23.092 -26.131 30.215  1.000 23.427 0 362  LEU A CD2 1 ? 
ATOM   2711 N  N   . ILE A  1 340 ? -19.489 -26.165 26.857  1.000 19.853 0 363  ILE A N   1 ? 
ATOM   2712 C  CA  . ILE A  1 340 ? -18.421 -25.172 26.808  1.000 19.907 0 363  ILE A CA  1 ? 
ATOM   2713 C  C   . ILE A  1 340 ? -19.052 -23.799 26.657  1.000 18.840 0 363  ILE A C   1 ? 
ATOM   2714 O  O   . ILE A  1 340 ? -19.846 -23.540 25.753  1.000 18.975 0 363  ILE A O   1 ? 
ATOM   2715 C  CB  . ILE A  1 340 ? -17.490 -25.443 25.621  1.000 22.476 0 363  ILE A CB  1 ? 
ATOM   2716 C  CG1 . ILE A  1 340 ? -17.011 -26.900 25.607  1.000 23.468 0 363  ILE A CG1 1 ? 
ATOM   2717 C  CG2 . ILE A  1 340 ? -16.344 -24.439 25.622  1.000 22.531 0 363  ILE A CG2 1 ? 
ATOM   2718 C  CD1 . ILE A  1 340 ? -16.209 -27.259 24.398  1.000 21.795 0 363  ILE A CD1 1 ? 
ATOM   2719 N  N   . SER A  1 341 ? -18.706 -22.900 27.566  1.000 20.904 0 364  SER A N   1 ? 
ATOM   2720 C  CA  . SER A  1 341 ? -19.000 -21.497 27.379  1.000 19.064 0 364  SER A CA  1 ? 
ATOM   2721 C  C   . SER A  1 341 ? -17.803 -20.906 26.665  1.000 18.732 0 364  SER A C   1 ? 
ATOM   2722 O  O   . SER A  1 341 ? -16.679 -21.203 27.074  1.000 21.257 0 364  SER A O   1 ? 
ATOM   2723 C  CB  . SER A  1 341 ? -19.198 -20.824 28.732  1.000 21.348 0 364  SER A CB  1 ? 
ATOM   2724 O  OG  . SER A  1 341 ? -19.528 -19.443 28.584  1.000 23.325 0 364  SER A OG  1 ? 
ATOM   2725 N  N   . LEU A  1 342 ? -18.009 -20.093 25.623  1.000 17.087 0 365  LEU A N   1 ? 
ATOM   2726 C  CA  . LEU A  1 342 ? -16.846 -19.547 24.945  1.000 18.849 0 365  LEU A CA  1 ? 
ATOM   2727 C  C   . LEU A  1 342 ? -17.221 -18.202 24.369  1.000 17.062 0 365  LEU A C   1 ? 
ATOM   2728 O  O   . LEU A  1 342 ? -18.403 -17.875 24.183  1.000 18.390 0 365  LEU A O   1 ? 
ATOM   2729 C  CB  . LEU A  1 342 ? -16.322 -20.547 23.896  1.000 18.598 0 365  LEU A CB  1 ? 
ATOM   2730 C  CG  . LEU A  1 342 ? -17.331 -21.037 22.853  1.000 21.181 0 365  LEU A CG  1 ? 
ATOM   2731 C  CD1 . LEU A  1 342 ? -17.597 -19.957 21.824  1.000 23.346 0 365  LEU A CD1 1 ? 
ATOM   2732 C  CD2 . LEU A  1 342 ? -16.841 -22.298 22.169  1.000 21.242 0 365  LEU A CD2 1 ? 
ATOM   2733 N  N   . GLY A  1 343 ? -16.190 -17.411 24.131  1.000 18.646 0 366  GLY A N   1 ? 
ATOM   2734 C  CA  . GLY A  1 343 ? -16.331 -16.147 23.411  1.000 17.192 0 366  GLY A CA  1 ? 
ATOM   2735 C  C   . GLY A  1 343 ? -16.533 -14.936 24.311  1.000 16.146 0 366  GLY A C   1 ? 
ATOM   2736 O  O   . GLY A  1 343 ? -16.718 -15.045 25.501  1.000 16.984 0 366  GLY A O   1 ? 
ATOM   2737 N  N   . GLN A  1 344 ? -16.567 -13.784 23.652  1.000 17.032 0 367  GLN A N   1 ? 
ATOM   2738 C  CA  . GLN A  1 344 ? -16.608 -12.458 24.237  1.000 18.689 0 367  GLN A CA  1 ? 
ATOM   2739 C  C   . GLN A  1 344 ? -17.609 -11.604 23.451  1.000 19.416 0 367  GLN A C   1 ? 
ATOM   2740 O  O   . GLN A  1 344 ? -17.648 -11.674 22.222  1.000 19.825 0 367  GLN A O   1 ? 
ATOM   2741 C  CB  . GLN A  1 344 ? -15.212 -11.848 24.177  1.000 19.777 0 367  GLN A CB  1 ? 
ATOM   2742 C  CG  . GLN A  1 344 ? -14.196 -12.611 25.014  1.000 19.986 0 367  GLN A CG  1 ? 
ATOM   2743 C  CD  . GLN A  1 344 ? -12.813 -12.028 24.831  1.000 23.740 0 367  GLN A CD  1 ? 
ATOM   2744 O  OE1 . GLN A  1 344 ? -12.288 -11.992 23.727  1.000 22.673 0 367  GLN A OE1 1 ? 
ATOM   2745 N  NE2 . GLN A  1 344 ? -12.213 -11.525 25.898  1.000 22.201 0 367  GLN A NE2 1 ? 
ATOM   2746 N  N   . HIS A  1 345 ? -18.343 -10.753 24.185  1.000 20.709 0 368  HIS A N   1 ? 
ATOM   2747 C  CA  . HIS A  1 345 ? -19.328 -9.796  23.696  1.000 22.267 0 368  HIS A CA  1 ? 
ATOM   2748 C  C   . HIS A  1 345 ? -20.672 -10.489 23.534  1.000 22.149 0 368  HIS A C   1 ? 
ATOM   2749 O  O   . HIS A  1 345 ? -20.749 -11.630 23.071  1.000 21.946 0 368  HIS A O   1 ? 
ATOM   2750 C  CB  . HIS A  1 345 ? -18.861 -9.036  22.448  1.000 23.805 0 368  HIS A CB  1 ? 
ATOM   2751 C  CG  . HIS A  1 345 ? -19.810 -7.968  21.994  1.000 25.547 0 368  HIS A CG  1 ? 
ATOM   2752 N  ND1 . HIS A  1 345 ? -21.000 -8.191  21.326  1.000 23.862 0 368  HIS A ND1 1 ? 
ATOM   2753 C  CD2 . HIS A  1 345 ? -19.664 -6.639  22.062  1.000 30.179 0 368  HIS A CD2 1 ? 
ATOM   2754 C  CE1 . HIS A  1 345 ? -21.548 -7.022  21.008  1.000 25.726 0 368  HIS A CE1 1 ? 
ATOM   2755 N  NE2 . HIS A  1 345 ? -20.766 -6.069  21.465  1.000 27.434 0 368  HIS A NE2 1 ? 
ATOM   2756 N  N   . LYS A  1 346 ? -21.735 -9.770  23.910  1.000 21.260 0 369  LYS A N   1 ? 
ATOM   2757 C  CA  . LYS A  1 346 ? -23.065 -10.379 23.964  1.000 25.116 0 369  LYS A CA  1 ? 
ATOM   2758 C  C   . LYS A  1 346 ? -23.524 -10.932 22.603  1.000 23.397 0 369  LYS A C   1 ? 
ATOM   2759 O  O   . LYS A  1 346 ? -24.407 -11.766 22.568  1.000 23.028 0 369  LYS A O   1 ? 
ATOM   2760 C  CB  . LYS A  1 346 ? -24.093 -9.357  24.491  1.000 28.983 0 369  LYS A CB  1 ? 
ATOM   2761 C  CG  . LYS A  1 346 ? -24.286 -8.127  23.615  1.000 33.362 0 369  LYS A CG  1 ? 
ATOM   2762 C  CD  . LYS A  1 346 ? -25.349 -7.159  24.121  1.000 41.938 0 369  LYS A CD  1 ? 
ATOM   2763 C  CE  . LYS A  1 346 ? -25.577 -6.019  23.150  1.000 48.292 0 369  LYS A CE  1 ? 
ATOM   2764 N  NZ  . LYS A  1 346 ? -26.350 -4.917  23.763  1.000 55.301 0 369  LYS A NZ  1 ? 
ATOM   2765 N  N   . ASN A  1 347 ? -23.022 -10.401 21.488  1.000 22.775 0 370  ASN A N   1 ? 
ATOM   2766 C  CA  . ASN A  1 347 ? -23.441 -10.870 20.177  1.000 24.716 0 370  ASN A CA  1 ? 
ATOM   2767 C  C   . ASN A  1 347 ? -22.612 -12.061 19.675  1.000 23.838 0 370  ASN A C   1 ? 
ATOM   2768 O  O   . ASN A  1 347 ? -22.929 -12.610 18.624  1.000 23.370 0 370  ASN A O   1 ? 
ATOM   2769 C  CB  . ASN A  1 347 ? -23.360 -9.725  19.163  1.000 27.999 0 370  ASN A CB  1 ? 
ATOM   2770 C  CG  . ASN A  1 347 ? -24.422 -8.675  19.413  1.000 31.399 0 370  ASN A CG  1 ? 
ATOM   2771 O  OD1 . ASN A  1 347 ? -25.446 -8.948  20.024  1.000 31.985 0 370  ASN A OD1 1 ? 
ATOM   2772 N  ND2 . ASN A  1 347 ? -24.180 -7.465  18.956  1.000 35.226 0 370  ASN A ND2 1 ? 
ATOM   2773 N  N   . HIS A  1 348 ? -21.569 -12.470 20.417  1.000 22.334 0 371  HIS A N   1 ? 
ATOM   2774 C  CA  . HIS A  1 348 ? -20.604 -13.459 19.958  1.000 20.472 0 371  HIS A CA  1 ? 
ATOM   2775 C  C   . HIS A  1 348 ? -20.432 -14.641 20.918  1.000 22.326 0 371  HIS A C   1 ? 
ATOM   2776 O  O   . HIS A  1 348 ? -20.130 -15.761 20.489  1.000 22.693 0 371  HIS A O   1 ? 
ATOM   2777 C  CB  . HIS A  1 348 ? -19.249 -12.780 19.805  1.000 18.419 0 371  HIS A CB  1 ? 
ATOM   2778 C  CG  . HIS A  1 348 ? -19.201 -11.681 18.797  1.000 18.674 0 371  HIS A CG  1 ? 
ATOM   2779 N  ND1 . HIS A  1 348 ? -18.617 -11.872 17.561  1.000 19.964 0 371  HIS A ND1 1 ? 
ATOM   2780 C  CD2 . HIS A  1 348 ? -19.637 -10.403 18.832  1.000 20.785 0 371  HIS A CD2 1 ? 
ATOM   2781 C  CE1 . HIS A  1 348 ? -18.624 -10.694 16.916  1.000 23.509 0 371  HIS A CE1 1 ? 
ATOM   2782 N  NE2 . HIS A  1 348 ? -19.274 -9.797  17.665  1.000 21.008 0 371  HIS A NE2 1 ? 
ATOM   2783 N  N   . ARG A  1 349 ? -20.570 -14.408 22.224  1.000 20.120 0 372  ARG A N   1 ? 
ATOM   2784 C  CA  . ARG A  1 349 ? -20.362 -15.491 23.192  1.000 16.781 0 372  ARG A CA  1 ? 
ATOM   2785 C  C   . ARG A  1 349 ? -21.479 -16.526 23.094  1.000 19.173 0 372  ARG A C   1 ? 
ATOM   2786 O  O   . ARG A  1 349 ? -22.639 -16.187 22.842  1.000 21.643 0 372  ARG A O   1 ? 
ATOM   2787 C  CB  . ARG A  1 349 ? -20.189 -14.860 24.578  1.000 17.819 0 372  ARG A CB  1 ? 
ATOM   2788 C  CG  . ARG A  1 349 ? -21.409 -14.155 25.155  1.000 17.173 0 372  ARG A CG  1 ? 
ATOM   2789 C  CD  . ARG A  1 349 ? -21.008 -13.168 26.234  1.000 18.485 0 372  ARG A CD  1 ? 
ATOM   2790 N  NE  . ARG A  1 349 ? -22.173 -12.515 26.794  1.000 22.058 0 372  ARG A NE  1 ? 
ATOM   2791 C  CZ  . ARG A  1 349 ? -22.144 -11.331 27.402  1.000 22.323 0 372  ARG A CZ  1 ? 
ATOM   2792 N  NH1 . ARG A  1 349 ? -23.257 -10.823 27.919  1.000 22.595 0 372  ARG A NH1 1 ? 
ATOM   2793 N  NH2 . ARG A  1 349 ? -21.015 -10.655 27.464  1.000 18.122 0 372  ARG A NH2 1 ? 
ATOM   2794 N  N   . ARG A  1 350 ? -21.138 -17.794 23.348  1.000 19.346 0 373  ARG A N   1 ? 
ATOM   2795 C  CA  . ARG A  1 350 ? -22.075 -18.885 23.190  1.000 21.847 0 373  ARG A CA  1 ? 
ATOM   2796 C  C   . ARG A  1 350 ? -21.786 -19.970 24.219  1.000 21.495 0 373  ARG A C   1 ? 
ATOM   2797 O  O   . ARG A  1 350 ? -20.642 -20.126 24.668  1.000 20.999 0 373  ARG A O   1 ? 
ATOM   2798 C  CB  . ARG A  1 350 ? -21.927 -19.574 21.828  1.000 25.381 0 373  ARG A CB  1 ? 
ATOM   2799 C  CG  . ARG A  1 350 ? -22.006 -18.616 20.658  1.000 26.721 0 373  ARG A CG  1 ? 
ATOM   2800 C  CD  . ARG A  1 350 ? -23.426 -18.216 20.391  1.000 32.142 0 373  ARG A CD  1 ? 
ATOM   2801 N  NE  . ARG A  1 350 ? -23.476 -17.282 19.277  1.000 32.720 0 373  ARG A NE  1 ? 
ATOM   2802 C  CZ  . ARG A  1 350 ? -23.733 -15.985 19.384  1.000 34.910 0 373  ARG A CZ  1 ? 
ATOM   2803 N  NH1 . ARG A  1 350 ? -23.798 -15.396 20.561  1.000 29.480 0 373  ARG A NH1 1 ? 
ATOM   2804 N  NH2 . ARG A  1 350 ? -23.816 -15.254 18.285  1.000 41.147 0 373  ARG A NH2 1 ? 
ATOM   2805 N  N   . LEU A  1 351 ? -22.841 -20.733 24.528  1.000 19.252 0 374  LEU A N   1 ? 
ATOM   2806 C  CA  . LEU A  1 351 ? -22.751 -22.017 25.197  1.000 18.534 0 374  LEU A CA  1 ? 
ATOM   2807 C  C   . LEU A  1 351 ? -23.017 -23.086 24.146  1.000 19.856 0 374  LEU A C   1 ? 
ATOM   2808 O  O   . LEU A  1 351 ? -23.976 -22.964 23.381  1.000 22.174 0 374  LEU A O   1 ? 
ATOM   2809 C  CB  . LEU A  1 351 ? -23.777 -22.098 26.321  1.000 23.472 0 374  LEU A CB  1 ? 
ATOM   2810 C  CG  . LEU A  1 351 ? -23.402 -21.397 27.625  1.000 24.786 0 374  LEU A CG  1 ? 
ATOM   2811 C  CD1 . LEU A  1 351 ? -24.628 -20.948 28.369  1.000 25.660 0 374  LEU A CD1 1 ? 
ATOM   2812 C  CD2 . LEU A  1 351 ? -22.583 -22.299 28.504  1.000 25.304 0 374  LEU A CD2 1 ? 
ATOM   2813 N  N   . VAL A  1 352 ? -22.117 -24.070 24.072  1.000 19.911 0 375  VAL A N   1 ? 
ATOM   2814 C  CA  . VAL A  1 352 ? -22.058 -25.045 22.988  1.000 21.158 0 375  VAL A CA  1 ? 
ATOM   2815 C  C   . VAL A  1 352 ? -21.888 -26.415 23.636  1.000 21.750 0 375  VAL A C   1 ? 
ATOM   2816 O  O   . VAL A  1 352 ? -21.084 -26.534 24.532  1.000 22.170 0 375  VAL A O   1 ? 
ATOM   2817 C  CB  . VAL A  1 352 ? -20.859 -24.763 22.058  1.000 23.560 0 375  VAL A CB  1 ? 
ATOM   2818 C  CG1 . VAL A  1 352 ? -20.826 -25.675 20.840  1.000 25.338 0 375  VAL A CG1 1 ? 
ATOM   2819 C  CG2 . VAL A  1 352 ? -20.836 -23.309 21.599  1.000 22.134 0 375  VAL A CG2 1 ? 
ATOM   2820 N  N   . ILE A  1 353 ? -22.548 -27.444 23.105  1.000 20.925 0 376  ILE A N   1 ? 
ATOM   2821 C  CA  . ILE A  1 353 ? -22.318 -28.808 23.537  1.000 22.295 0 376  ILE A CA  1 ? 
ATOM   2822 C  C   . ILE A  1 353 ? -21.550 -29.563 22.454  1.000 21.010 0 376  ILE A C   1 ? 
ATOM   2823 O  O   . ILE A  1 353 ? -21.950 -29.572 21.289  1.000 22.664 0 376  ILE A O   1 ? 
ATOM   2824 C  CB  . ILE A  1 353 ? -23.656 -29.508 23.863  1.000 24.084 0 376  ILE A CB  1 ? 
ATOM   2825 C  CG1 . ILE A  1 353 ? -24.411 -28.763 24.960  1.000 24.253 0 376  ILE A CG1 1 ? 
ATOM   2826 C  CG2 . ILE A  1 353 ? -23.399 -30.966 24.230  1.000 21.621 0 376  ILE A CG2 1 ? 
ATOM   2827 C  CD1 . ILE A  1 353 ? -25.782 -29.350 25.297  1.000 26.236 0 376  ILE A CD1 1 ? 
ATOM   2828 N  N   A VAL A  1 354 ? -20.511 -30.270 22.905  0.500 22.113 0 377  VAL A N   1 ? 
ATOM   2829 N  N   B VAL A  1 354 ? -20.395 -30.113 22.822  0.500 20.092 0 377  VAL A N   1 ? 
ATOM   2830 C  CA  A VAL A  1 354 ? -19.552 -30.948 22.052  0.500 23.572 0 377  VAL A CA  1 ? 
ATOM   2831 C  CA  B VAL A  1 354 ? -19.621 -30.938 21.912  0.500 20.302 0 377  VAL A CA  1 ? 
ATOM   2832 C  C   A VAL A  1 354 ? -19.425 -32.401 22.498  0.500 24.854 0 377  VAL A C   1 ? 
ATOM   2833 C  C   B VAL A  1 354 ? -19.686 -32.372 22.420  0.500 21.477 0 377  VAL A C   1 ? 
ATOM   2834 O  O   A VAL A  1 354 ? -19.292 -32.686 23.685  0.500 22.455 0 377  VAL A O   1 ? 
ATOM   2835 O  O   B VAL A  1 354 ? -20.049 -32.601 23.571  0.500 17.829 0 377  VAL A O   1 ? 
ATOM   2836 C  CB  A VAL A  1 354 ? -18.185 -30.239 22.103  0.500 23.311 0 377  VAL A CB  1 ? 
ATOM   2837 C  CB  B VAL A  1 354 ? -18.176 -30.421 21.743  0.500 18.577 0 377  VAL A CB  1 ? 
ATOM   2838 C  CG1 A VAL A  1 354 ? -17.118 -31.021 21.362  0.500 24.366 0 377  VAL A CG1 1 ? 
ATOM   2839 C  CG1 B VAL A  1 354 ? -18.192 -28.990 21.241  0.500 18.715 0 377  VAL A CG1 1 ? 
ATOM   2840 C  CG2 A VAL A  1 354 ? -18.287 -28.816 21.575  0.500 24.090 0 377  VAL A CG2 1 ? 
ATOM   2841 C  CG2 B VAL A  1 354 ? -17.341 -30.520 23.007  0.500 18.400 0 377  VAL A CG2 1 ? 
ATOM   2842 N  N   . ASP A  1 355 ? -19.354 -33.307 21.511  1.000 24.892 0 378  ASP A N   1 ? 
ATOM   2843 C  CA  . ASP A  1 355 ? -19.316 -34.743 21.774  1.000 24.405 0 378  ASP A CA  1 ? 
ATOM   2844 C  C   . ASP A  1 355 ? -17.902 -35.264 21.523  1.000 21.652 0 378  ASP A C   1 ? 
ATOM   2845 O  O   . ASP A  1 355 ? -17.311 -35.021 20.472  1.000 23.950 0 378  ASP A O   1 ? 
ATOM   2846 C  CB  . ASP A  1 355 ? -20.280 -35.476 20.829  1.000 25.586 0 378  ASP A CB  1 ? 
ATOM   2847 C  CG  . ASP A  1 355 ? -20.626 -36.905 21.243  1.000 29.389 0 378  ASP A CG  1 ? 
ATOM   2848 O  OD1 . ASP A  1 355 ? -19.720 -37.731 21.330  1.000 29.121 0 378  ASP A OD1 1 ? 
ATOM   2849 O  OD2 . ASP A  1 355 ? -21.812 -37.169 21.473  1.000 30.091 0 378  ASP A OD2 1 ? 
ATOM   2850 N  N   . ARG A  1 356 ? -17.368 -36.043 22.454  1.000 21.595 0 379  ARG A N   1 ? 
ATOM   2851 C  CA  . ARG A  1 356 ? -15.985 -36.470 22.369  1.000 22.900 0 379  ARG A CA  1 ? 
ATOM   2852 C  C   . ARG A  1 356 ? -15.784 -37.427 21.196  1.000 23.932 0 379  ARG A C   1 ? 
ATOM   2853 O  O   . ARG A  1 356 ? -14.681 -37.575 20.701  1.000 25.838 0 379  ARG A O   1 ? 
ATOM   2854 C  CB  . ARG A  1 356 ? -15.562 -37.140 23.682  1.000 27.410 0 379  ARG A CB  1 ? 
ATOM   2855 C  CG  . ARG A  1 356 ? -16.279 -38.460 23.927  1.000 28.843 0 379  ARG A CG  1 ? 
ATOM   2856 C  CD  . ARG A  1 356 ? -16.033 -39.016 25.316  1.000 29.916 0 379  ARG A CD  1 ? 
ATOM   2857 N  NE  . ARG A  1 356 ? -14.657 -39.356 25.607  1.000 32.325 0 379  ARG A NE  1 ? 
ATOM   2858 C  CZ  . ARG A  1 356 ? -14.257 -39.715 26.835  1.000 36.075 0 379  ARG A CZ  1 ? 
ATOM   2859 N  NH1 . ARG A  1 356 ? -15.125 -39.747 27.846  1.000 35.227 0 379  ARG A NH1 1 ? 
ATOM   2860 N  NH2 . ARG A  1 356 ? -13.000 -40.050 27.041  1.000 32.528 0 379  ARG A NH2 1 ? 
ATOM   2861 N  N   . ARG A  1 357 ? -16.845 -38.065 20.718  1.000 25.163 0 380  ARG A N   1 ? 
ATOM   2862 C  CA  . ARG A  1 357 ? -16.672 -39.017 19.622  1.000 27.788 0 380  ARG A CA  1 ? 
ATOM   2863 C  C   . ARG A  1 357 ? -16.472 -38.254 18.322  1.000 27.012 0 380  ARG A C   1 ? 
ATOM   2864 O  O   . ARG A  1 357 ? -15.741 -38.693 17.446  1.000 29.606 0 380  ARG A O   1 ? 
ATOM   2865 C  CB  . ARG A  1 357 ? -17.910 -39.913 19.527  1.000 29.469 0 380  ARG A CB  1 ? 
ATOM   2866 C  CG  . ARG A  1 357 ? -18.082 -40.799 20.755  1.000 31.951 0 380  ARG A CG  1 ? 
ATOM   2867 C  CD  . ARG A  1 357 ? -19.434 -41.464 20.773  1.000 30.849 0 380  ARG A CD  1 ? 
ATOM   2868 N  NE  . ARG A  1 357 ? -20.482 -40.484 20.933  1.000 30.993 0 380  ARG A NE  1 ? 
ATOM   2869 C  CZ  . ARG A  1 357 ? -21.750 -40.797 21.125  1.000 35.468 0 380  ARG A CZ  1 ? 
ATOM   2870 N  NH1 . ARG A  1 357 ? -22.132 -42.066 21.077  1.000 40.551 0 380  ARG A NH1 1 ? 
ATOM   2871 N  NH2 . ARG A  1 357 ? -22.632 -39.851 21.372  1.000 35.420 0 380  ARG A NH2 1 ? 
ATOM   2872 N  N   . TRP A  1 358 ? -17.079 -37.066 18.247  1.000 25.112 0 381  TRP A N   1 ? 
ATOM   2873 C  CA  . TRP A  1 358 ? -16.778 -36.125 17.179  1.000 23.286 0 381  TRP A CA  1 ? 
ATOM   2874 C  C   . TRP A  1 358 ? -15.334 -35.643 17.285  1.000 21.118 0 381  TRP A C   1 ? 
ATOM   2875 O  O   . TRP A  1 358 ? -14.665 -35.525 16.279  1.000 22.692 0 381  TRP A O   1 ? 
ATOM   2876 C  CB  . TRP A  1 358 ? -17.822 -35.003 17.214  1.000 23.160 0 381  TRP A CB  1 ? 
ATOM   2877 C  CG  . TRP A  1 358 ? -17.543 -33.812 16.343  1.000 24.107 0 381  TRP A CG  1 ? 
ATOM   2878 C  CD1 . TRP A  1 358 ? -17.964 -33.550 15.070  1.000 25.912 0 381  TRP A CD1 1 ? 
ATOM   2879 C  CD2 . TRP A  1 358 ? -16.832 -32.643 16.785  1.000 23.782 0 381  TRP A CD2 1 ? 
ATOM   2880 N  NE1 . TRP A  1 358 ? -17.513 -32.320 14.667  1.000 26.760 0 381  TRP A NE1 1 ? 
ATOM   2881 C  CE2 . TRP A  1 358 ? -16.832 -31.731 15.703  1.000 24.807 0 381  TRP A CE2 1 ? 
ATOM   2882 C  CE3 . TRP A  1 358 ? -16.220 -32.294 17.982  1.000 24.778 0 381  TRP A CE3 1 ? 
ATOM   2883 C  CZ2 . TRP A  1 358 ? -16.229 -30.484 15.802  1.000 24.629 0 381  TRP A CZ2 1 ? 
ATOM   2884 C  CZ3 . TRP A  1 358 ? -15.643 -31.047 18.085  1.000 24.681 0 381  TRP A CZ3 1 ? 
ATOM   2885 C  CH2 . TRP A  1 358 ? -15.634 -30.169 17.004  1.000 23.595 0 381  TRP A CH2 1 ? 
ATOM   2886 N  N   . VAL A  1 359 ? -14.823 -35.377 18.492  1.000 22.364 0 382  VAL A N   1 ? 
ATOM   2887 C  CA  . VAL A  1 359 ? -13.430 -34.968 18.623  1.000 21.820 0 382  VAL A CA  1 ? 
ATOM   2888 C  C   . VAL A  1 359 ? -12.500 -36.049 18.072  1.000 24.414 0 382  VAL A C   1 ? 
ATOM   2889 O  O   . VAL A  1 359 ? -11.448 -35.729 17.522  1.000 20.716 0 382  VAL A O   1 ? 
ATOM   2890 C  CB  . VAL A  1 359 ? -13.053 -34.580 20.068  1.000 21.534 0 382  VAL A CB  1 ? 
ATOM   2891 C  CG1 . VAL A  1 359 ? -11.600 -34.117 20.153  1.000 20.349 0 382  VAL A CG1 1 ? 
ATOM   2892 C  CG2 . VAL A  1 359 ? -14.014 -33.530 20.629  1.000 21.524 0 382  VAL A CG2 1 ? 
ATOM   2893 N  N   . GLY A  1 360 ? -12.866 -37.319 18.263  1.000 24.770 0 383  GLY A N   1 ? 
ATOM   2894 C  CA  . GLY A  1 360 ? -12.035 -38.445 17.879  1.000 25.641 0 383  GLY A CA  1 ? 
ATOM   2895 C  C   . GLY A  1 360 ? -12.236 -38.913 16.435  1.000 26.736 0 383  GLY A C   1 ? 
ATOM   2896 O  O   . GLY A  1 360 ? -11.576 -39.839 16.011  1.000 26.158 0 383  GLY A O   1 ? 
ATOM   2897 N  N   . ALA A  1 361 ? -13.053 -38.220 15.637  1.000 26.068 0 384  ALA A N   1 ? 
ATOM   2898 C  CA  . ALA A  1 361 ? -13.312 -38.641 14.267  1.000 25.751 0 384  ALA A CA  1 ? 
ATOM   2899 C  C   . ALA A  1 361 ? -12.048 -38.485 13.424  1.000 26.981 0 384  ALA A C   1 ? 
ATOM   2900 O  O   . ALA A  1 361 ? -11.211 -37.627 13.705  1.000 24.424 0 384  ALA A O   1 ? 
ATOM   2901 C  CB  . ALA A  1 361 ? -14.462 -37.846 13.697  1.000 26.428 0 384  ALA A CB  1 ? 
ATOM   2902 N  N   . LYS A  1 362 ? -11.917 -39.309 12.364  1.000 23.148 0 385  LYS A N   1 ? 
ATOM   2903 C  CA  . LYS A  1 362 ? -10.720 -39.295 11.540  1.000 25.394 0 385  LYS A CA  1 ? 
ATOM   2904 C  C   . LYS A  1 362 ? -11.008 -38.833 10.108  1.000 23.037 0 385  LYS A C   1 ? 
ATOM   2905 O  O   . LYS A  1 362 ? -10.084 -38.817 9.306   1.000 26.246 0 385  LYS A O   1 ? 
ATOM   2906 C  CB  . LYS A  1 362 ? -10.082 -40.691 11.584  1.000 32.418 0 385  LYS A CB  1 ? 
ATOM   2907 C  CG  . LYS A  1 362 ? -9.589  -41.135 12.965  1.000 33.863 0 385  LYS A CG  1 ? 
ATOM   2908 C  CD  . LYS A  1 362 ? -8.640  -40.136 13.611  1.000 42.126 0 385  LYS A CD  1 ? 
ATOM   2909 C  CE  . LYS A  1 362 ? -8.336  -40.363 15.082  1.000 48.711 0 385  LYS A CE  1 ? 
ATOM   2910 N  NZ  . LYS A  1 362 ? -7.548  -39.220 15.604  1.000 50.756 0 385  LYS A NZ  1 ? 
ATOM   2911 N  N   . THR A  1 363 ? -12.266 -38.476 9.789   1.000 24.171 0 386  THR A N   1 ? 
ATOM   2912 C  CA  . THR A  1 363 ? -12.564 -37.945 8.468   1.000 23.533 0 386  THR A CA  1 ? 
ATOM   2913 C  C   . THR A  1 363 ? -13.479 -36.732 8.525   1.000 22.276 0 386  THR A C   1 ? 
ATOM   2914 O  O   . THR A  1 363 ? -14.202 -36.508 9.498   1.000 22.051 0 386  THR A O   1 ? 
ATOM   2915 C  CB  . THR A  1 363 ? -13.260 -38.969 7.561   1.000 25.979 0 386  THR A CB  1 ? 
ATOM   2916 O  OG1 . THR A  1 363 ? -14.568 -39.236 8.059   1.000 29.515 0 386  THR A OG1 1 ? 
ATOM   2917 C  CG2 . THR A  1 363 ? -12.491 -40.264 7.429   1.000 28.620 0 386  THR A CG2 1 ? 
ATOM   2918 N  N   . ARG A  1 364 ? -13.415 -35.951 7.454   1.000 23.378 0 387  ARG A N   1 ? 
ATOM   2919 C  CA  . ARG A  1 364 ? -14.336 -34.853 7.267   1.000 25.011 0 387  ARG A CA  1 ? 
ATOM   2920 C  C   . ARG A  1 364 ? -14.423 -34.545 5.792   1.000 22.473 0 387  ARG A C   1 ? 
ATOM   2921 O  O   . ARG A  1 364 ? -13.441 -34.748 5.073   1.000 21.765 0 387  ARG A O   1 ? 
ATOM   2922 C  CB  . ARG A  1 364 ? -13.859 -33.597 8.007   1.000 21.999 0 387  ARG A CB  1 ? 
ATOM   2923 C  CG  . ARG A  1 364 ? -14.959 -32.585 8.281   1.000 20.837 0 387  ARG A CG  1 ? 
ATOM   2924 C  CD  . ARG A  1 364 ? -14.416 -31.292 8.886   1.000 20.945 0 387  ARG A CD  1 ? 
ATOM   2925 N  NE  . ARG A  1 364 ? -15.512 -30.433 9.271   1.000 19.891 0 387  ARG A NE  1 ? 
ATOM   2926 C  CZ  . ARG A  1 364 ? -15.425 -29.129 9.501   1.000 20.494 0 387  ARG A CZ  1 ? 
ATOM   2927 N  NH1 . ARG A  1 364 ? -14.295 -28.478 9.306   1.000 22.063 0 387  ARG A NH1 1 ? 
ATOM   2928 N  NH2 . ARG A  1 364 ? -16.507 -28.459 9.844   1.000 20.211 0 387  ARG A NH2 1 ? 
ATOM   2929 N  N   . ALA A  1 365 ? -15.572 -34.013 5.367   1.000 21.678 0 388  ALA A N   1 ? 
ATOM   2930 C  CA  . ALA A  1 365 ? -15.710 -33.607 3.973   1.000 21.669 0 388  ALA A CA  1 ? 
ATOM   2931 C  C   . ALA A  1 365 ? -16.589 -32.366 3.864   1.000 21.225 0 388  ALA A C   1 ? 
ATOM   2932 O  O   . ALA A  1 365 ? -17.424 -32.075 4.720   1.000 23.504 0 388  ALA A O   1 ? 
ATOM   2933 C  CB  . ALA A  1 365 ? -16.277 -34.729 3.142   1.000 23.098 0 388  ALA A CB  1 ? 
ATOM   2934 N  N   . THR A  1 366 ? -16.397 -31.635 2.769   1.000 21.465 0 389  THR A N   1 ? 
ATOM   2935 C  CA  . THR A  1 366 ? -17.054 -30.351 2.579   1.000 20.144 0 389  THR A CA  1 ? 
ATOM   2936 C  C   . THR A  1 366 ? -17.264 -30.091 1.089   1.000 19.637 0 389  THR A C   1 ? 
ATOM   2937 O  O   . THR A  1 366 ? -16.549 -30.618 0.228   1.000 18.963 0 389  THR A O   1 ? 
ATOM   2938 C  CB  . THR A  1 366 ? -16.250 -29.222 3.238   1.000 19.130 0 389  THR A CB  1 ? 
ATOM   2939 O  OG1 . THR A  1 366 ? -17.072 -28.056 3.307   1.000 18.935 0 389  THR A OG1 1 ? 
ATOM   2940 C  CG2 . THR A  1 366 ? -14.943 -28.923 2.526   1.000 19.790 0 389  THR A CG2 1 ? 
ATOM   2941 N  N   . GLN A  1 367 ? -18.209 -29.193 0.812   1.000 19.255 0 390  GLN A N   1 ? 
ATOM   2942 C  CA  . GLN A  1 367 ? -18.452 -28.638 -0.508  1.000 20.061 0 390  GLN A CA  1 ? 
ATOM   2943 C  C   . GLN A  1 367 ? -18.711 -27.160 -0.275  1.000 18.900 0 390  GLN A C   1 ? 
ATOM   2944 O  O   . GLN A  1 367 ? -19.549 -26.789 0.565   1.000 19.261 0 390  GLN A O   1 ? 
ATOM   2945 C  CB  . GLN A  1 367 ? -19.612 -29.367 -1.209  1.000 20.494 0 390  GLN A CB  1 ? 
ATOM   2946 C  CG  . GLN A  1 367 ? -19.719 -29.129 -2.712  1.000 21.492 0 390  GLN A CG  1 ? 
ATOM   2947 C  CD  . GLN A  1 367 ? -20.333 -27.792 -3.081  1.000 21.105 0 390  GLN A CD  1 ? 
ATOM   2948 O  OE1 . GLN A  1 367 ? -21.307 -27.330 -2.480  1.000 21.861 0 390  GLN A OE1 1 ? 
ATOM   2949 N  NE2 . GLN A  1 367 ? -19.783 -27.160 -4.092  1.000 20.177 0 390  GLN A NE2 1 ? 
ATOM   2950 N  N   . THR A  1 368 ? -17.975 -26.313 -0.976  1.000 18.493 0 391  THR A N   1 ? 
ATOM   2951 C  CA  . THR A  1 368 ? -17.962 -24.907 -0.610  1.000 19.178 0 391  THR A CA  1 ? 
ATOM   2952 C  C   . THR A  1 368 ? -19.376 -24.308 -0.656  1.000 19.269 0 391  THR A C   1 ? 
ATOM   2953 O  O   . THR A  1 368 ? -19.741 -23.479 0.180   1.000 20.005 0 391  THR A O   1 ? 
ATOM   2954 C  CB  . THR A  1 368 ? -17.020 -24.101 -1.494  1.000 19.643 0 391  THR A CB  1 ? 
ATOM   2955 O  OG1 . THR A  1 368 ? -17.296 -24.362 -2.867  1.000 17.476 0 391  THR A OG1 1 ? 
ATOM   2956 C  CG2 . THR A  1 368 ? -15.558 -24.410 -1.178  1.000 19.971 0 391  THR A CG2 1 ? 
ATOM   2957 N  N   . GLY A  1 369 ? -20.075 -24.581 -1.740  1.000 20.180 0 392  GLY A N   1 ? 
ATOM   2958 C  CA  . GLY A  1 369 ? -21.386 -24.004 -1.929  1.000 19.173 0 392  GLY A CA  1 ? 
ATOM   2959 C  C   . GLY A  1 369 ? -22.375 -24.358 -0.821  1.000 22.203 0 392  GLY A C   1 ? 
ATOM   2960 O  O   . GLY A  1 369 ? -23.183 -23.522 -0.467  1.000 26.349 0 392  GLY A O   1 ? 
ATOM   2961 N  N   . LYS A  1 370 ? -22.339 -25.588 -0.307  1.000 22.100 0 393  LYS A N   1 ? 
ATOM   2962 C  CA  . LYS A  1 370 ? -23.259 -26.019 0.741   1.000 23.739 0 393  LYS A CA  1 ? 
ATOM   2963 C  C   . LYS A  1 370 ? -22.798 -25.546 2.119   1.000 22.410 0 393  LYS A C   1 ? 
ATOM   2964 O  O   . LYS A  1 370 ? -23.615 -25.361 3.000   1.000 21.670 0 393  LYS A O   1 ? 
ATOM   2965 C  CB  . LYS A  1 370 ? -23.312 -27.544 0.859   1.000 28.172 0 393  LYS A CB  1 ? 
ATOM   2966 C  CG  . LYS A  1 370 ? -23.965 -28.261 -0.300  1.000 42.569 0 393  LYS A CG  1 ? 
ATOM   2967 C  CD  . LYS A  1 370 ? -23.880 -29.776 -0.214  1.000 47.862 0 393  LYS A CD  1 ? 
ATOM   2968 C  CE  . LYS A  1 370 ? -24.057 -30.381 -1.588  1.000 53.962 0 393  LYS A CE  1 ? 
ATOM   2969 N  NZ  . LYS A  1 370 ? -25.271 -29.820 -2.233  1.000 55.709 0 393  LYS A NZ  1 ? 
ATOM   2970 N  N   . ASP A  1 371 ? -21.483 -25.426 2.331   1.000 19.367 0 394  ASP A N   1 ? 
ATOM   2971 C  CA  . ASP A  1 371 ? -20.909 -25.443 3.668   1.000 19.954 0 394  ASP A CA  1 ? 
ATOM   2972 C  C   . ASP A  1 371 ? -20.160 -24.159 4.011   1.000 19.404 0 394  ASP A C   1 ? 
ATOM   2973 O  O   . ASP A  1 371 ? -19.528 -24.099 5.068   1.000 20.914 0 394  ASP A O   1 ? 
ATOM   2974 C  CB  . ASP A  1 371 ? -19.975 -26.654 3.853   1.000 20.178 0 394  ASP A CB  1 ? 
ATOM   2975 C  CG  . ASP A  1 371 ? -20.697 -27.998 3.723   1.000 23.530 0 394  ASP A CG  1 ? 
ATOM   2976 O  OD1 . ASP A  1 371 ? -21.817 -28.102 4.237   1.000 20.314 0 394  ASP A OD1 1 ? 
ATOM   2977 O  OD2 . ASP A  1 371 ? -20.153 -28.940 3.100   1.000 22.193 0 394  ASP A OD2 1 ? 
ATOM   2978 N  N   . LEU A  1 372 ? -20.213 -23.154 3.143   1.000 18.875 0 395  LEU A N   1 ? 
ATOM   2979 C  CA  . LEU A  1 372 ? -19.417 -21.949 3.330   1.000 19.727 0 395  LEU A CA  1 ? 
ATOM   2980 C  C   . LEU A  1 372 ? -19.676 -21.324 4.696   1.000 20.016 0 395  LEU A C   1 ? 
ATOM   2981 O  O   . LEU A  1 372 ? -18.768 -20.890 5.395   1.000 21.516 0 395  LEU A O   1 ? 
ATOM   2982 C  CB  . LEU A  1 372 ? -19.755 -20.909 2.259   1.000 19.784 0 395  LEU A CB  1 ? 
ATOM   2983 C  CG  . LEU A  1 372 ? -18.661 -19.885 1.947   1.000 20.219 0 395  LEU A CG  1 ? 
ATOM   2984 C  CD1 . LEU A  1 372 ? -17.439 -20.549 1.356   1.000 21.433 0 395  LEU A CD1 1 ? 
ATOM   2985 C  CD2 . LEU A  1 372 ? -19.179 -18.824 1.007   1.000 22.786 0 395  LEU A CD2 1 ? 
ATOM   2986 N  N   . ASP A  1 373 ? -20.949 -21.153 5.027   1.000 20.987 0 396  ASP A N   1 ? 
ATOM   2987 C  CA  . ASP A  1 373 ? -21.306 -20.354 6.185   1.000 22.996 0 396  ASP A CA  1 ? 
ATOM   2988 C  C   . ASP A  1 373 ? -20.819 -21.019 7.469   1.000 20.711 0 396  ASP A C   1 ? 
ATOM   2989 O  O   . ASP A  1 373 ? -20.420 -20.335 8.418   1.000 21.896 0 396  ASP A O   1 ? 
ATOM   2990 C  CB  . ASP A  1 373 ? -22.820 -20.111 6.230   1.000 23.880 0 396  ASP A CB  1 ? 
ATOM   2991 C  CG  . ASP A  1 373 ? -23.322 -19.106 5.212   1.000 28.619 0 396  ASP A CG  1 ? 
ATOM   2992 O  OD1 . ASP A  1 373 ? -22.512 -18.528 4.439   1.000 28.712 0 396  ASP A OD1 1 ? 
ATOM   2993 O  OD2 . ASP A  1 373 ? -24.543 -18.915 5.174   1.000 30.530 0 396  ASP A OD2 1 ? 
ATOM   2994 N  N   . SER A  1 374 ? -20.922 -22.337 7.528   1.000 21.863 0 397  SER A N   1 ? 
ATOM   2995 C  CA  . SER A  1 374 ? -20.674 -23.038 8.775   1.000 24.502 0 397  SER A CA  1 ? 
ATOM   2996 C  C   . SER A  1 374 ? -19.220 -23.464 8.912   1.000 23.650 0 397  SER A C   1 ? 
ATOM   2997 O  O   . SER A  1 374 ? -18.758 -23.619 10.033  1.000 25.691 0 397  SER A O   1 ? 
ATOM   2998 C  CB  . SER A  1 374 ? -21.576 -24.243 8.937   1.000 30.978 0 397  SER A CB  1 ? 
ATOM   2999 O  OG  . SER A  1 374 ? -21.585 -25.048 7.774   1.000 39.544 0 397  SER A OG  1 ? 
ATOM   3000 N  N   . GLN A  1 375 ? -18.516 -23.712 7.798   1.000 19.311 0 398  GLN A N   1 ? 
ATOM   3001 C  CA  . GLN A  1 375 ? -17.226 -24.390 7.885   1.000 18.230 0 398  GLN A CA  1 ? 
ATOM   3002 C  C   . GLN A  1 375 ? -16.068 -23.634 7.244   1.000 18.575 0 398  GLN A C   1 ? 
ATOM   3003 O  O   . GLN A  1 375 ? -14.906 -24.037 7.441   1.000 20.385 0 398  GLN A O   1 ? 
ATOM   3004 C  CB  . GLN A  1 375 ? -17.299 -25.738 7.154   1.000 20.243 0 398  GLN A CB  1 ? 
ATOM   3005 C  CG  . GLN A  1 375 ? -18.451 -26.615 7.583   1.000 21.045 0 398  GLN A CG  1 ? 
ATOM   3006 C  CD  . GLN A  1 375 ? -18.390 -27.973 6.920   1.000 22.799 0 398  GLN A CD  1 ? 
ATOM   3007 O  OE1 . GLN A  1 375 ? -17.439 -28.323 6.218   1.000 22.191 0 398  GLN A OE1 1 ? 
ATOM   3008 N  NE2 . GLN A  1 375 ? -19.441 -28.741 7.140   1.000 24.693 0 398  GLN A NE2 1 ? 
ATOM   3009 N  N   . TRP A  1 376 ? -16.320 -22.546 6.502   1.000 19.140 0 399  TRP A N   1 ? 
ATOM   3010 C  CA  . TRP A  1 376 ? -15.204 -21.940 5.772   1.000 18.785 0 399  TRP A CA  1 ? 
ATOM   3011 C  C   . TRP A  1 376 ? -14.811 -20.580 6.337   1.000 18.615 0 399  TRP A C   1 ? 
ATOM   3012 O  O   . TRP A  1 376 ? -15.643 -19.738 6.587   1.000 16.730 0 399  TRP A O   1 ? 
ATOM   3013 C  CB  . TRP A  1 376 ? -15.491 -21.827 4.274   1.000 17.831 0 399  TRP A CB  1 ? 
ATOM   3014 C  CG  . TRP A  1 376 ? -15.384 -23.154 3.593   1.000 17.064 0 399  TRP A CG  1 ? 
ATOM   3015 C  CD1 . TRP A  1 376 ? -16.305 -24.146 3.531   1.000 17.788 0 399  TRP A CD1 1 ? 
ATOM   3016 C  CD2 . TRP A  1 376 ? -14.215 -23.654 2.931   1.000 17.633 0 399  TRP A CD2 1 ? 
ATOM   3017 N  NE1 . TRP A  1 376 ? -15.810 -25.222 2.859   1.000 18.659 0 399  TRP A NE1 1 ? 
ATOM   3018 C  CE2 . TRP A  1 376 ? -14.518 -24.954 2.481   1.000 18.020 0 399  TRP A CE2 1 ? 
ATOM   3019 C  CE3 . TRP A  1 376 ? -12.958 -23.117 2.683   1.000 18.870 0 399  TRP A CE3 1 ? 
ATOM   3020 C  CZ2 . TRP A  1 376 ? -13.606 -25.738 1.795   1.000 19.807 0 399  TRP A CZ2 1 ? 
ATOM   3021 C  CZ3 . TRP A  1 376 ? -12.057 -23.900 2.002   1.000 18.800 0 399  TRP A CZ3 1 ? 
ATOM   3022 C  CH2 . TRP A  1 376 ? -12.379 -25.178 1.557   1.000 19.205 0 399  TRP A CH2 1 ? 
ATOM   3023 N  N   . THR A  1 377 ? -13.496 -20.363 6.499   1.000 17.843 0 400  THR A N   1 ? 
ATOM   3024 C  CA  . THR A  1 377 ? -12.959 -19.050 6.822   1.000 16.642 0 400  THR A CA  1 ? 
ATOM   3025 C  C   . THR A  1 377 ? -12.482 -18.411 5.526   1.000 16.989 0 400  THR A C   1 ? 
ATOM   3026 O  O   . THR A  1 377 ? -11.583 -18.945 4.843   1.000 17.009 0 400  THR A O   1 ? 
ATOM   3027 C  CB  . THR A  1 377 ? -11.858 -19.146 7.879   1.000 15.966 0 400  THR A CB  1 ? 
ATOM   3028 O  OG1 . THR A  1 377 ? -12.445 -19.559 9.100   1.000 19.175 0 400  THR A OG1 1 ? 
ATOM   3029 C  CG2 . THR A  1 377 ? -11.190 -17.817 8.079   1.000 18.478 0 400  THR A CG2 1 ? 
ATOM   3030 N  N   . ILE A  1 378 ? -13.080 -17.264 5.185   1.000 16.060 0 401  ILE A N   1 ? 
ATOM   3031 C  CA  . ILE A  1 378 ? -12.822 -16.614 3.913   1.000 16.873 0 401  ILE A CA  1 ? 
ATOM   3032 C  C   . ILE A  1 378 ? -12.676 -15.117 4.052   1.000 17.227 0 401  ILE A C   1 ? 
ATOM   3033 O  O   . ILE A  1 378 ? -12.598 -14.437 3.037   1.000 18.194 0 401  ILE A O   1 ? 
ATOM   3034 C  CB  . ILE A  1 378 ? -13.968 -16.901 2.928   1.000 19.184 0 401  ILE A CB  1 ? 
ATOM   3035 C  CG1 . ILE A  1 378 ? -15.283 -16.267 3.397   1.000 19.510 0 401  ILE A CG1 1 ? 
ATOM   3036 C  CG2 . ILE A  1 378 ? -14.116 -18.394 2.694   1.000 17.984 0 401  ILE A CG2 1 ? 
ATOM   3037 C  CD1 . ILE A  1 378 ? -16.368 -16.341 2.317   1.000 19.635 0 401  ILE A CD1 1 ? 
ATOM   3038 N  N   . HIS A  1 379 ? -12.675 -14.595 5.280   1.000 17.145 0 402  HIS A N   1 ? 
ATOM   3039 C  CA  . HIS A  1 379 ? -12.726 -13.152 5.432   1.000 15.864 0 402  HIS A CA  1 ? 
ATOM   3040 C  C   . HIS A  1 379 ? -11.403 -12.493 5.079   1.000 16.404 0 402  HIS A C   1 ? 
ATOM   3041 O  O   . HIS A  1 379 ? -10.330 -12.988 5.425   1.000 18.821 0 402  HIS A O   1 ? 
ATOM   3042 C  CB  . HIS A  1 379 ? -13.219 -12.706 6.811   1.000 16.276 0 402  HIS A CB  1 ? 
ATOM   3043 C  CG  . HIS A  1 379 ? -12.551 -13.283 8.000   1.000 16.916 0 402  HIS A CG  1 ? 
ATOM   3044 N  ND1 . HIS A  1 379 ? -12.866 -14.536 8.467   1.000 17.739 0 402  HIS A ND1 1 ? 
ATOM   3045 C  CD2 . HIS A  1 379 ? -11.683 -12.763 8.883   1.000 18.168 0 402  HIS A CD2 1 ? 
ATOM   3046 C  CE1 . HIS A  1 379 ? -12.143 -14.768 9.562   1.000 20.352 0 402  HIS A CE1 1 ? 
ATOM   3047 N  NE2 . HIS A  1 379 ? -11.437 -13.702 9.841   1.000 16.516 0 402  HIS A NE2 1 ? 
ATOM   3048 N  N   . THR A  1 380 ? -11.537 -11.301 4.492   1.000 16.025 0 403  THR A N   1 ? 
ATOM   3049 C  CA  . THR A  1 380 ? -10.474 -10.319 4.453   1.000 17.714 0 403  THR A CA  1 ? 
ATOM   3050 C  C   . THR A  1 380 ? -10.890 -9.148  5.344   1.000 18.189 0 403  THR A C   1 ? 
ATOM   3051 O  O   . THR A  1 380 ? -11.989 -9.131  5.882   1.000 19.233 0 403  THR A O   1 ? 
ATOM   3052 C  CB  . THR A  1 380 ? -10.148 -9.950  3.009   1.000 19.118 0 403  THR A CB  1 ? 
ATOM   3053 O  OG1 . THR A  1 380 ? -8.998  -9.116  2.993   1.000 21.029 0 403  THR A OG1 1 ? 
ATOM   3054 C  CG2 . THR A  1 380 ? -11.316 -9.282  2.318   1.000 18.180 0 403  THR A CG2 1 ? 
ATOM   3055 N  N   . TYR A  1 381 ? -9.964  -8.217  5.534   1.000 17.431 0 404  TYR A N   1 ? 
ATOM   3056 C  CA  . TYR A  1 381 ? -10.123 -7.083  6.435   1.000 16.506 0 404  TYR A CA  1 ? 
ATOM   3057 C  C   . TYR A  1 381 ? -9.987  -5.812  5.634   1.000 16.830 0 404  TYR A C   1 ? 
ATOM   3058 O  O   . TYR A  1 381 ? -9.145  -5.719  4.746   1.000 19.637 0 404  TYR A O   1 ? 
ATOM   3059 C  CB  . TYR A  1 381 ? -9.018  -7.092  7.490   1.000 17.815 0 404  TYR A CB  1 ? 
ATOM   3060 C  CG  . TYR A  1 381 ? -9.018  -8.342  8.347   1.000 17.056 0 404  TYR A CG  1 ? 
ATOM   3061 C  CD1 . TYR A  1 381 ? -9.799  -8.437  9.476   1.000 18.686 0 404  TYR A CD1 1 ? 
ATOM   3062 C  CD2 . TYR A  1 381 ? -8.246  -9.437  7.991   1.000 18.544 0 404  TYR A CD2 1 ? 
ATOM   3063 C  CE1 . TYR A  1 381 ? -9.791  -9.577  10.266  1.000 19.663 0 404  TYR A CE1 1 ? 
ATOM   3064 C  CE2 . TYR A  1 381 ? -8.235  -10.582 8.770   1.000 19.841 0 404  TYR A CE2 1 ? 
ATOM   3065 C  CZ  . TYR A  1 381 ? -9.000  -10.659 9.917   1.000 18.008 0 404  TYR A CZ  1 ? 
ATOM   3066 O  OH  . TYR A  1 381 ? -9.000  -11.759 10.759  1.000 18.977 0 404  TYR A OH  1 ? 
ATOM   3067 N  N   . ILE A  1 382 ? -10.821 -4.842  5.994   1.000 18.880 0 405  ILE A N   1 ? 
ATOM   3068 C  CA  . ILE A  1 382 ? -10.616 -3.443  5.666   1.000 19.989 0 405  ILE A CA  1 ? 
ATOM   3069 C  C   . ILE A  1 382 ? -9.626  -2.892  6.673   1.000 18.206 0 405  ILE A C   1 ? 
ATOM   3070 O  O   . ILE A  1 382 ? -9.942  -2.799  7.874   1.000 18.059 0 405  ILE A O   1 ? 
ATOM   3071 C  CB  . ILE A  1 382 ? -11.963 -2.709  5.764   1.000 20.524 0 405  ILE A CB  1 ? 
ATOM   3072 C  CG1 . ILE A  1 382 ? -12.976 -3.324  4.804   1.000 21.406 0 405  ILE A CG1 1 ? 
ATOM   3073 C  CG2 . ILE A  1 382 ? -11.815 -1.204  5.544   1.000 20.664 0 405  ILE A CG2 1 ? 
ATOM   3074 C  CD1 . ILE A  1 382 ? -14.384 -3.032  5.208   1.000 24.583 0 405  ILE A CD1 1 ? 
ATOM   3075 N  N   . PRO A  1 383 ? -8.390  -2.551  6.240   1.000 19.807 0 406  PRO A N   1 ? 
ATOM   3076 C  CA  . PRO A  1 383 ? -7.332  -2.222  7.186   1.000 21.020 0 406  PRO A CA  1 ? 
ATOM   3077 C  C   . PRO A  1 383 ? -7.436  -0.788  7.690   1.000 20.595 0 406  PRO A C   1 ? 
ATOM   3078 O  O   . PRO A  1 383 ? -6.556  0.010   7.464   1.000 21.508 0 406  PRO A O   1 ? 
ATOM   3079 C  CB  . PRO A  1 383 ? -6.055  -2.496  6.381   1.000 21.062 0 406  PRO A CB  1 ? 
ATOM   3080 C  CG  . PRO A  1 383 ? -6.452  -2.226  4.947   1.000 19.625 0 406  PRO A CG  1 ? 
ATOM   3081 C  CD  . PRO A  1 383 ? -7.898  -2.663  4.847   1.000 19.898 0 406  PRO A CD  1 ? 
ATOM   3082 N  N   . GLN A  1 384 ? -8.560  -0.471  8.320   1.000 20.706 0 407  GLN A N   1 ? 
ATOM   3083 C  CA  . GLN A  1 384 ? -8.805  0.808   8.973   1.000 19.924 0 407  GLN A CA  1 ? 
ATOM   3084 C  C   . GLN A  1 384 ? -9.243  0.484   10.397  1.000 20.696 0 407  GLN A C   1 ? 
ATOM   3085 O  O   . GLN A  1 384 ? -10.201 -0.274  10.608  1.000 20.654 0 407  GLN A O   1 ? 
ATOM   3086 C  CB  . GLN A  1 384 ? -9.879  1.586   8.233   1.000 21.820 0 407  GLN A CB  1 ? 
ATOM   3087 C  CG  . GLN A  1 384 ? -9.585  1.903   6.768   1.000 23.315 0 407  GLN A CG  1 ? 
ATOM   3088 C  CD  . GLN A  1 384 ? -8.428  2.851   6.626   1.000 26.636 0 407  GLN A CD  1 ? 
ATOM   3089 O  OE1 . GLN A  1 384 ? -8.217  3.692   7.492   1.000 24.463 0 407  GLN A OE1 1 ? 
ATOM   3090 N  NE2 . GLN A  1 384 ? -7.661  2.690   5.554   1.000 25.385 0 407  GLN A NE2 1 ? 
ATOM   3091 N  N   . LYS A  1 385 ? -8.479  0.950   11.382  1.000 21.504 0 408  LYS A N   1 ? 
ATOM   3092 C  CA  . LYS A  1 385 ? -8.754  0.567   12.762  1.000 24.432 0 408  LYS A CA  1 ? 
ATOM   3093 C  C   . LYS A  1 385 ? -10.148 1.033   13.171  1.000 23.957 0 408  LYS A C   1 ? 
ATOM   3094 O  O   . LYS A  1 385 ? -10.549 2.153   12.847  1.000 22.568 0 408  LYS A O   1 ? 
ATOM   3095 C  CB  . LYS A  1 385 ? -7.717  1.146   13.723  1.000 31.869 0 408  LYS A CB  1 ? 
ATOM   3096 C  CG  . LYS A  1 385 ? -8.001  0.751   15.167  1.000 39.290 0 408  LYS A CG  1 ? 
ATOM   3097 C  CD  . LYS A  1 385 ? -6.984  1.187   16.144  1.000 45.456 0 408  LYS A CD  1 ? 
ATOM   3098 C  CE  . LYS A  1 385 ? -5.771  0.308   16.066  1.000 46.544 0 408  LYS A CE  1 ? 
ATOM   3099 N  NZ  . LYS A  1 385 ? -4.912  0.544   17.245  1.000 59.085 0 408  LYS A NZ  1 ? 
ATOM   3100 N  N   . LYS A  1 386 ? -10.862 0.154   13.878  1.000 20.119 0 409  LYS A N   1 ? 
ATOM   3101 C  CA  . LYS A  1 386 ? -12.223 0.393   14.320  1.000 23.350 0 409  LYS A CA  1 ? 
ATOM   3102 C  C   . LYS A  1 386 ? -12.316 0.071   15.799  1.000 25.296 0 409  LYS A C   1 ? 
ATOM   3103 O  O   . LYS A  1 386 ? -11.738 -0.901  16.277  1.000 26.116 0 409  LYS A O   1 ? 
ATOM   3104 C  CB  . LYS A  1 386 ? -13.214 -0.430  13.506  1.000 22.167 0 409  LYS A CB  1 ? 
ATOM   3105 C  CG  . LYS A  1 386 ? -13.267 -0.058  12.036  1.000 21.684 0 409  LYS A CG  1 ? 
ATOM   3106 C  CD  . LYS A  1 386 ? -13.915 1.278   11.849  1.000 25.093 0 409  LYS A CD  1 ? 
ATOM   3107 C  CE  . LYS A  1 386 ? -13.316 2.101   10.740  1.000 26.822 0 409  LYS A CE  1 ? 
ATOM   3108 N  NZ  . LYS A  1 386 ? -14.105 3.327   10.463  1.000 27.301 0 409  LYS A NZ  1 ? 
ATOM   3109 N  N   . GLY A  1 387 ? -12.998 0.945   16.519  1.000 29.592 0 410  GLY A N   1 ? 
ATOM   3110 C  CA  . GLY A  1 387 ? -13.116 0.824   17.966  1.000 32.029 0 410  GLY A CA  1 ? 
ATOM   3111 C  C   . GLY A  1 387 ? -11.743 0.762   18.619  1.000 27.415 0 410  GLY A C   1 ? 
ATOM   3112 O  O   . GLY A  1 387 ? -10.804 1.416   18.184  1.000 30.391 0 410  GLY A O   1 ? 
ATOM   3113 N  N   . HIS A  1 388 ? -11.614 -0.094  19.634  1.000 28.524 0 411  HIS A N   1 ? 
ATOM   3114 C  CA  . HIS A  1 388 ? -10.381 -0.135  20.407  1.000 27.430 0 411  HIS A CA  1 ? 
ATOM   3115 C  C   . HIS A  1 388 ? -9.273  -0.862  19.646  1.000 24.560 0 411  HIS A C   1 ? 
ATOM   3116 O  O   . HIS A  1 388 ? -8.112  -0.445  19.670  1.000 25.744 0 411  HIS A O   1 ? 
ATOM   3117 C  CB  . HIS A  1 388 ? -10.678 -0.749  21.781  1.000 29.765 0 411  HIS A CB  1 ? 
ATOM   3118 C  CG  . HIS A  1 388 ? -9.472  -0.863  22.647  1.000 30.316 0 411  HIS A CG  1 ? 
ATOM   3119 N  ND1 . HIS A  1 388 ? -8.999  0.149   23.456  1.000 28.754 0 411  HIS A ND1 1 ? 
ATOM   3120 C  CD2 . HIS A  1 388 ? -8.671  -1.932  22.858  1.000 29.747 0 411  HIS A CD2 1 ? 
ATOM   3121 C  CE1 . HIS A  1 388 ? -7.909  -0.290  24.092  1.000 29.074 0 411  HIS A CE1 1 ? 
ATOM   3122 N  NE2 . HIS A  1 388 ? -7.683  -1.555  23.733  1.000 27.157 0 411  HIS A NE2 1 ? 
ATOM   3123 N  N   . CYS A  1 389 ? -9.609  -1.976  18.981  1.000 23.100 0 412  CYS A N   1 ? 
ATOM   3124 C  CA  . CYS A  1 389 ? -8.585  -2.844  18.421  1.000 22.903 0 412  CYS A CA  1 ? 
ATOM   3125 C  C   . CYS A  1 389 ? -9.145  -3.781  17.345  1.000 24.041 0 412  CYS A C   1 ? 
ATOM   3126 O  O   . CYS A  1 389 ? -8.720  -4.922  17.272  1.000 23.163 0 412  CYS A O   1 ? 
ATOM   3127 C  CB  . CYS A  1 389 ? -7.956  -3.688  19.529  1.000 24.979 0 412  CYS A CB  1 ? 
ATOM   3128 S  SG  . CYS A  1 389 ? -9.155  -4.596  20.555  1.000 29.893 0 412  CYS A SG  1 ? 
ATOM   3129 N  N   . SER A  1 390 ? -10.115 -3.334  16.543  1.000 19.363 0 413  SER A N   1 ? 
ATOM   3130 C  CA  . SER A  1 390 ? -10.757 -4.223  15.599  1.000 20.213 0 413  SER A CA  1 ? 
ATOM   3131 C  C   . SER A  1 390 ? -10.584 -3.745  14.158  1.000 23.073 0 413  SER A C   1 ? 
ATOM   3132 O  O   . SER A  1 390 ? -10.231 -2.596  13.902  1.000 22.124 0 413  SER A O   1 ? 
ATOM   3133 C  CB  . SER A  1 390 ? -12.226 -4.350  15.932  1.000 24.231 0 413  SER A CB  1 ? 
ATOM   3134 O  OG  . SER A  1 390 ? -12.367 -4.861  17.246  1.000 28.438 0 413  SER A OG  1 ? 
ATOM   3135 N  N   . TYR A  1 391 ? -10.818 -4.668  13.219  1.000 21.220 0 414  TYR A N   1 ? 
ATOM   3136 C  CA  . TYR A  1 391 ? -11.037 -4.335  11.831  1.000 19.496 0 414  TYR A CA  1 ? 
ATOM   3137 C  C   . TYR A  1 391 ? -12.417 -4.841  11.419  1.000 20.835 0 414  TYR A C   1 ? 
ATOM   3138 O  O   . TYR A  1 391 ? -12.840 -5.923  11.847  1.000 23.523 0 414  TYR A O   1 ? 
ATOM   3139 C  CB  . TYR A  1 391 ? -10.081 -5.003  10.852  1.000 18.929 0 414  TYR A CB  1 ? 
ATOM   3140 C  CG  . TYR A  1 391 ? -8.662  -4.497  10.772  1.000 20.657 0 414  TYR A CG  1 ? 
ATOM   3141 C  CD1 . TYR A  1 391 ? -8.349  -3.153  10.902  1.000 19.082 0 414  TYR A CD1 1 ? 
ATOM   3142 C  CD2 . TYR A  1 391 ? -7.659  -5.368  10.423  1.000 20.026 0 414  TYR A CD2 1 ? 
ATOM   3143 C  CE1 . TYR A  1 391 ? -7.045  -2.722  10.738  1.000 20.306 0 414  TYR A CE1 1 ? 
ATOM   3144 C  CE2 . TYR A  1 391 ? -6.358  -4.942  10.210  1.000 21.397 0 414  TYR A CE2 1 ? 
ATOM   3145 C  CZ  . TYR A  1 391 ? -6.054  -3.610  10.369  1.000 21.240 0 414  TYR A CZ  1 ? 
ATOM   3146 O  OH  . TYR A  1 391 ? -4.775  -3.225  10.160  1.000 22.029 0 414  TYR A OH  1 ? 
ATOM   3147 N  N   . ASN A  1 392 ? -13.087 -4.102  10.527  1.000 19.044 0 415  ASN A N   1 ? 
ATOM   3148 C  CA  . ASN A  1 392 ? -14.281 -4.611  9.876   1.000 19.195 0 415  ASN A CA  1 ? 
ATOM   3149 C  C   . ASN A  1 392 ? -13.830 -5.473  8.709   1.000 18.508 0 415  ASN A C   1 ? 
ATOM   3150 O  O   . ASN A  1 392 ? -12.660 -5.416  8.335   1.000 19.130 0 415  ASN A O   1 ? 
ATOM   3151 C  CB  . ASN A  1 392 ? -15.202 -3.476  9.443   1.000 19.884 0 415  ASN A CB  1 ? 
ATOM   3152 C  CG  . ASN A  1 392 ? -15.907 -2.882  10.637  1.000 22.410 0 415  ASN A CG  1 ? 
ATOM   3153 O  OD1 . ASN A  1 392 ? -16.190 -3.583  11.598  1.000 22.759 0 415  ASN A OD1 1 ? 
ATOM   3154 N  ND2 . ASN A  1 392 ? -16.143 -1.590  10.613  1.000 22.020 0 415  ASN A ND2 1 ? 
ATOM   3155 N  N   . ARG A  1 393 ? -14.731 -6.300  8.210   1.000 17.942 0 416  ARG A N   1 ? 
ATOM   3156 C  CA  . ARG A  1 393 ? -14.364 -7.315  7.242   1.000 19.828 0 416  ARG A CA  1 ? 
ATOM   3157 C  C   . ARG A  1 393 ? -15.247 -7.291  6.001   1.000 18.600 0 416  ARG A C   1 ? 
ATOM   3158 O  O   . ARG A  1 393 ? -16.337 -6.701  5.961   1.000 20.368 0 416  ARG A O   1 ? 
ATOM   3159 C  CB  . ARG A  1 393 ? -14.422 -8.711  7.880   1.000 19.458 0 416  ARG A CB  1 ? 
ATOM   3160 C  CG  . ARG A  1 393 ? -13.513 -8.913  9.096   1.000 17.468 0 416  ARG A CG  1 ? 
ATOM   3161 C  CD  . ARG A  1 393 ? -14.131 -8.588  10.452  1.000 17.986 0 416  ARG A CD  1 ? 
ATOM   3162 N  NE  . ARG A  1 393 ? -13.217 -8.753  11.579  1.000 18.046 0 416  ARG A NE  1 ? 
ATOM   3163 C  CZ  . ARG A  1 393 ? -12.933 -9.935  12.147  1.000 20.236 0 416  ARG A CZ  1 ? 
ATOM   3164 N  NH1 . ARG A  1 393 ? -13.412 -11.055 11.637  1.000 20.006 0 416  ARG A NH1 1 ? 
ATOM   3165 N  NH2 . ARG A  1 393 ? -12.078 -10.011 13.154  1.000 21.561 0 416  ARG A NH2 1 ? 
ATOM   3166 N  N   . LYS A  1 394 ? -14.800 -8.074  5.007   1.000 17.323 0 417  LYS A N   1 ? 
ATOM   3167 C  CA  . LYS A  1 394 ? -15.628 -8.488  3.881   1.000 18.069 0 417  LYS A CA  1 ? 
ATOM   3168 C  C   . LYS A  1 394 ? -15.325 -9.953  3.596   1.000 19.784 0 417  LYS A C   1 ? 
ATOM   3169 O  O   . LYS A  1 394 ? -14.200 -10.412 3.858   1.000 17.967 0 417  LYS A O   1 ? 
ATOM   3170 C  CB  . LYS A  1 394 ? -15.276 -7.713  2.607   1.000 17.142 0 417  LYS A CB  1 ? 
ATOM   3171 C  CG  . LYS A  1 394 ? -15.446 -6.206  2.693   1.000 20.407 0 417  LYS A CG  1 ? 
ATOM   3172 C  CD  . LYS A  1 394 ? -15.142 -5.468  1.403   1.000 21.570 0 417  LYS A CD  1 ? 
ATOM   3173 C  CE  . LYS A  1 394 ? -15.088 -3.966  1.573   1.000 22.901 0 417  LYS A CE  1 ? 
ATOM   3174 N  NZ  . LYS A  1 394 ? -15.165 -3.308  0.261   1.000 22.454 0 417  LYS A NZ  1 ? 
ATOM   3175 N  N   . PRO A  1 395 ? -16.236 -10.700 2.964   1.000 19.864 0 418  PRO A N   1 ? 
ATOM   3176 C  CA  . PRO A  1 395 ? -15.863 -11.997 2.387   1.000 19.395 0 418  PRO A CA  1 ? 
ATOM   3177 C  C   . PRO A  1 395 ? -14.832 -11.784 1.289   1.000 19.252 0 418  PRO A C   1 ? 
ATOM   3178 O  O   . PRO A  1 395 ? -14.987 -10.910 0.455   1.000 19.185 0 418  PRO A O   1 ? 
ATOM   3179 C  CB  . PRO A  1 395 ? -17.199 -12.531 1.830   1.000 22.798 0 418  PRO A CB  1 ? 
ATOM   3180 C  CG  . PRO A  1 395 ? -18.040 -11.308 1.585   1.000 22.539 0 418  PRO A CG  1 ? 
ATOM   3181 C  CD  . PRO A  1 395 ? -17.631 -10.315 2.649   1.000 21.043 0 418  PRO A CD  1 ? 
ATOM   3182 N  N   . SER A  1 396 ? -13.770 -12.586 1.251   1.000 18.588 0 419  SER A N   1 ? 
ATOM   3183 C  CA  . SER A  1 396 ? -12.725 -12.372 0.253   1.000 18.907 0 419  SER A CA  1 ? 
ATOM   3184 C  C   . SER A  1 396 ? -12.976 -13.179 -1.030  1.000 19.280 0 419  SER A C   1 ? 
ATOM   3185 O  O   . SER A  1 396 ? -12.244 -13.053 -2.019  1.000 19.427 0 419  SER A O   1 ? 
ATOM   3186 C  CB  . SER A  1 396 ? -11.352 -12.733 0.821   1.000 18.331 0 419  SER A CB  1 ? 
ATOM   3187 O  OG  . SER A  1 396 ? -11.161 -14.147 0.783   1.000 17.910 0 419  SER A OG  1 ? 
ATOM   3188 N  N   . ALA A  1 397 ? -14.023 -14.005 -1.007  1.000 19.065 0 420  ALA A N   1 ? 
ATOM   3189 C  CA  . ALA A  1 397 ? -14.340 -14.910 -2.106  1.000 19.911 0 420  ALA A CA  1 ? 
ATOM   3190 C  C   . ALA A  1 397 ? -15.862 -15.072 -2.133  1.000 19.220 0 420  ALA A C   1 ? 
ATOM   3191 O  O   . ALA A  1 397 ? -16.481 -15.026 -1.088  1.000 18.989 0 420  ALA A O   1 ? 
ATOM   3192 C  CB  . ALA A  1 397 ? -13.717 -16.252 -1.871  1.000 22.308 0 420  ALA A CB  1 ? 
ATOM   3193 N  N   . GLU A  1 398 ? -16.432 -15.349 -3.299  1.000 22.894 0 421  GLU A N   1 ? 
ATOM   3194 C  CA  . GLU A  1 398 ? -17.882 -15.540 -3.376  1.000 23.002 0 421  GLU A CA  1 ? 
ATOM   3195 C  C   . GLU A  1 398 ? -18.183 -16.787 -4.197  1.000 22.224 0 421  GLU A C   1 ? 
ATOM   3196 O  O   . GLU A  1 398 ? -17.389 -17.253 -5.008  1.000 19.363 0 421  GLU A O   1 ? 
ATOM   3197 C  CB  . GLU A  1 398 ? -18.628 -14.322 -3.945  1.000 28.258 0 421  GLU A CB  1 ? 
ATOM   3198 C  CG  . GLU A  1 398 ? -18.426 -14.110 -5.425  1.000 31.848 0 421  GLU A CG  1 ? 
ATOM   3199 C  CD  . GLU A  1 398 ? -19.052 -12.854 -6.037  1.000 41.971 0 421  GLU A CD  1 ? 
ATOM   3200 O  OE1 . GLU A  1 398 ? -20.003 -12.289 -5.429  1.000 45.361 0 421  GLU A OE1 1 ? 
ATOM   3201 O  OE2 . GLU A  1 398 ? -18.592 -12.447 -7.154  1.000 44.624 0 421  GLU A OE2 1 ? 
ATOM   3202 N  N   . LEU A  1 399 ? -19.401 -17.272 -3.986  1.000 21.682 0 422  LEU A N   1 ? 
ATOM   3203 C  CA  . LEU A  1 399 ? -19.897 -18.438 -4.675  1.000 22.459 0 422  LEU A CA  1 ? 
ATOM   3204 C  C   . LEU A  1 399 ? -20.423 -18.027 -6.032  1.000 21.562 0 422  LEU A C   1 ? 
ATOM   3205 O  O   . LEU A  1 399 ? -21.026 -16.970 -6.182  1.000 21.947 0 422  LEU A O   1 ? 
ATOM   3206 C  CB  . LEU A  1 399 ? -21.013 -19.067 -3.842  1.000 21.604 0 422  LEU A CB  1 ? 
ATOM   3207 C  CG  . LEU A  1 399 ? -20.599 -19.773 -2.561  1.000 21.928 0 422  LEU A CG  1 ? 
ATOM   3208 C  CD1 . LEU A  1 399 ? -21.845 -20.275 -1.829  1.000 22.780 0 422  LEU A CD1 1 ? 
ATOM   3209 C  CD2 . LEU A  1 399 ? -19.634 -20.930 -2.800  1.000 19.978 0 422  LEU A CD2 1 ? 
ATOM   3210 N  N   . VAL A  1 400 ? -20.183 -18.898 -7.013  1.000 21.048 0 423  VAL A N   1 ? 
ATOM   3211 C  CA  . VAL A  1 400 ? -20.653 -18.715 -8.369  1.000 21.809 0 423  VAL A CA  1 ? 
ATOM   3212 C  C   . VAL A  1 400 ? -21.165 -20.062 -8.850  1.000 21.442 0 423  VAL A C   1 ? 
ATOM   3213 O  O   . VAL A  1 400 ? -20.834 -21.080 -8.257  1.000 18.737 0 423  VAL A O   1 ? 
ATOM   3214 C  CB  . VAL A  1 400 ? -19.559 -18.178 -9.310  1.000 22.571 0 423  VAL A CB  1 ? 
ATOM   3215 C  CG1 . VAL A  1 400 ? -19.067 -16.783 -8.895  1.000 23.964 0 423  VAL A CG1 1 ? 
ATOM   3216 C  CG2 . VAL A  1 400 ? -18.388 -19.144 -9.458  1.000 23.407 0 423  VAL A CG2 1 ? 
ATOM   3217 N  N   . GLN A  1 401 ? -21.949 -20.048 -9.937  1.000 21.685 0 424  GLN A N   1 ? 
ATOM   3218 C  CA  . GLN A  1 401 ? -22.424 -21.273 -10.595 1.000 22.773 0 424  GLN A CA  1 ? 
ATOM   3219 C  C   . GLN A  1 401 ? -21.268 -22.153 -11.079 1.000 19.355 0 424  GLN A C   1 ? 
ATOM   3220 O  O   . GLN A  1 401 ? -20.301 -21.666 -11.666 1.000 22.659 0 424  GLN A O   1 ? 
ATOM   3221 C  CB  . GLN A  1 401 ? -23.354 -20.864 -11.748 1.000 25.415 0 424  GLN A CB  1 ? 
ATOM   3222 C  CG  . GLN A  1 401 ? -23.814 -22.020 -12.635 1.000 26.445 0 424  GLN A CG  1 ? 
ATOM   3223 C  CD  . GLN A  1 401 ? -24.710 -23.009 -11.918 1.000 29.402 0 424  GLN A CD  1 ? 
ATOM   3224 O  OE1 . GLN A  1 401 ? -25.656 -22.653 -11.217 1.000 33.186 0 424  GLN A OE1 1 ? 
ATOM   3225 N  NE2 . GLN A  1 401 ? -24.432 -24.292 -12.087 1.000 28.567 0 424  GLN A NE2 1 ? 
ATOM   3226 N  N   . ASP A  1 402 ? -21.352 -23.470 -10.857 1.000 19.911 0 425  ASP A N   1 ? 
ATOM   3227 C  CA  . ASP A  1 402 ? -20.431 -24.402 -11.483 1.000 21.167 0 425  ASP A CA  1 ? 
ATOM   3228 C  C   . ASP A  1 402 ? -20.610 -24.286 -12.991 1.000 25.945 0 425  ASP A C   1 ? 
ATOM   3229 O  O   . ASP A  1 402 ? -21.727 -24.466 -13.474 1.000 23.334 0 425  ASP A O   1 ? 
ATOM   3230 C  CB  . ASP A  1 402 ? -20.674 -25.830 -11.005 1.000 22.183 0 425  ASP A CB  1 ? 
ATOM   3231 C  CG  . ASP A  1 402 ? -19.828 -26.924 -11.629 1.000 21.787 0 425  ASP A CG  1 ? 
ATOM   3232 O  OD1 . ASP A  1 402 ? -19.032 -26.615 -12.515 1.000 24.123 0 425  ASP A OD1 1 ? 
ATOM   3233 O  OD2 . ASP A  1 402 ? -19.950 -28.096 -11.178 1.000 22.777 0 425  ASP A OD2 1 ? 
ATOM   3234 N  N   . PRO A  1 403 ? -19.566 -23.943 -13.778 1.000 25.740 0 426  PRO A N   1 ? 
ATOM   3235 C  CA  . PRO A  1 403 ? -19.712 -23.812 -15.230 1.000 26.323 0 426  PRO A CA  1 ? 
ATOM   3236 C  C   . PRO A  1 403 ? -20.040 -25.121 -15.929 1.000 25.895 0 426  PRO A C   1 ? 
ATOM   3237 O  O   . PRO A  1 403 ? -20.466 -25.098 -17.066 1.000 25.680 0 426  PRO A O   1 ? 
ATOM   3238 C  CB  . PRO A  1 403 ? -18.333 -23.380 -15.740 1.000 31.922 0 426  PRO A CB  1 ? 
ATOM   3239 C  CG  . PRO A  1 403 ? -17.593 -22.911 -14.516 1.000 32.335 0 426  PRO A CG  1 ? 
ATOM   3240 C  CD  . PRO A  1 403 ? -18.208 -23.632 -13.336 1.000 28.143 0 426  PRO A CD  1 ? 
ATOM   3241 N  N   . SER A  1 404 ? -19.921 -26.249 -15.229 1.000 21.416 0 427  SER A N   1 ? 
ATOM   3242 C  CA  . SER A  1 404 ? -20.253 -27.551 -15.781 1.000 22.851 0 427  SER A CA  1 ? 
ATOM   3243 C  C   . SER A  1 404 ? -21.782 -27.728 -15.837 1.000 23.930 0 427  SER A C   1 ? 
ATOM   3244 O  O   . SER A  1 404 ? -22.278 -28.619 -16.527 1.000 26.585 0 427  SER A O   1 ? 
ATOM   3245 C  CB  . SER A  1 404 ? -19.625 -28.657 -14.957 1.000 24.116 0 427  SER A CB  1 ? 
ATOM   3246 O  OG  . SER A  1 404 ? -18.201 -28.633 -15.095 1.000 28.533 0 427  SER A OG  1 ? 
ATOM   3247 N  N   . GLY A  1 405 ? -22.522 -26.883 -15.120 1.000 24.047 0 428  GLY A N   1 ? 
ATOM   3248 C  CA  . GLY A  1 405 ? -23.964 -27.047 -14.976 1.000 26.803 0 428  GLY A CA  1 ? 
ATOM   3249 C  C   . GLY A  1 405 ? -24.326 -27.627 -13.617 1.000 26.928 0 428  GLY A C   1 ? 
ATOM   3250 O  O   . GLY A  1 405 ? -23.541 -27.575 -12.667 1.000 24.865 0 428  GLY A O   1 ? 
ATOM   3251 N  N   . GLY A  1 406 ? -25.563 -28.112 -13.490 1.000 24.416 0 429  GLY A N   1 ? 
ATOM   3252 C  CA  . GLY A  1 406 ? -26.040 -28.567 -12.198 1.000 24.276 0 429  GLY A CA  1 ? 
ATOM   3253 C  C   . GLY A  1 406 ? -26.387 -27.392 -11.290 1.000 22.806 0 429  GLY A C   1 ? 
ATOM   3254 O  O   . GLY A  1 406 ? -26.453 -26.262 -11.752 1.000 23.097 0 429  GLY A O   1 ? 
ATOM   3255 N  N   . THR A  1 407 ? -26.671 -27.682 -10.027 1.000 24.825 0 430  THR A N   1 ? 
ATOM   3256 C  CA  . THR A  1 407 ? -27.003 -26.660 -9.040  1.000 25.160 0 430  THR A CA  1 ? 
ATOM   3257 C  C   . THR A  1 407 ? -25.806 -26.310 -8.154  1.000 21.074 0 430  THR A C   1 ? 
ATOM   3258 O  O   . THR A  1 407 ? -25.878 -25.422 -7.317  1.000 21.716 0 430  THR A O   1 ? 
ATOM   3259 C  CB  . THR A  1 407 ? -28.141 -27.125 -8.131  1.000 25.580 0 430  THR A CB  1 ? 
ATOM   3260 O  OG1 . THR A  1 407 ? -27.819 -28.373 -7.513  1.000 24.136 0 430  THR A OG1 1 ? 
ATOM   3261 C  CG2 . THR A  1 407 ? -29.432 -27.286 -8.918  1.000 30.100 0 430  THR A CG2 1 ? 
ATOM   3262 N  N   . LYS A  1 408 ? -24.721 -27.050 -8.304  1.000 23.679 0 431  LYS A N   1 ? 
ATOM   3263 C  CA  . LYS A  1 408 ? -23.542 -26.798 -7.508  1.000 21.680 0 431  LYS A CA  1 ? 
ATOM   3264 C  C   . LYS A  1 408 ? -23.094 -25.334 -7.623  1.000 20.961 0 431  LYS A C   1 ? 
ATOM   3265 O  O   . LYS A  1 408 ? -22.949 -24.780 -8.729  1.000 20.100 0 431  LYS A O   1 ? 
ATOM   3266 C  CB  . LYS A  1 408 ? -22.527 -27.801 -8.034  1.000 27.245 0 431  LYS A CB  1 ? 
ATOM   3267 C  CG  . LYS A  1 408 ? -21.238 -27.884 -7.283  1.000 29.063 0 431  LYS A CG  1 ? 
ATOM   3268 C  CD  . LYS A  1 408 ? -20.433 -29.131 -7.671  1.000 30.552 0 431  LYS A CD  1 ? 
ATOM   3269 C  CE  . LYS A  1 408 ? -20.499 -30.190 -6.585  1.000 30.545 0 431  LYS A CE  1 ? 
ATOM   3270 N  NZ  . LYS A  1 408 ? -19.462 -31.213 -6.790  1.000 41.164 0 431  LYS A NZ  1 ? 
ATOM   3271 N  N   . LYS A  1 409 ? -22.804 -24.731 -6.454  1.000 21.094 0 432  LYS A N   1 ? 
ATOM   3272 C  CA  . LYS A  1 409 ? -22.165 -23.438 -6.382  1.000 20.396 0 432  LYS A CA  1 ? 
ATOM   3273 C  C   . LYS A  1 409 ? -20.759 -23.677 -5.837  1.000 21.210 0 432  LYS A C   1 ? 
ATOM   3274 O  O   . LYS A  1 409 ? -20.600 -24.540 -4.995  1.000 20.478 0 432  LYS A O   1 ? 
ATOM   3275 C  CB  . LYS A  1 409 ? -22.928 -22.515 -5.447  1.000 24.501 0 432  LYS A CB  1 ? 
ATOM   3276 C  CG  . LYS A  1 409 ? -24.369 -22.281 -5.855  1.000 31.926 0 432  LYS A CG  1 ? 
ATOM   3277 C  CD  . LYS A  1 409 ? -24.422 -21.548 -7.137  1.000 37.132 0 432  LYS A CD  1 ? 
ATOM   3278 C  CE  . LYS A  1 409 ? -25.833 -21.366 -7.646  1.000 48.885 0 432  LYS A CE  1 ? 
ATOM   3279 N  NZ  . LYS A  1 409 ? -26.431 -22.658 -8.058  1.000 58.723 0 432  LYS A NZ  1 ? 
ATOM   3280 N  N   . VAL A  1 410 ? -19.780 -22.933 -6.351  1.000 19.215 0 433  VAL A N   1 ? 
ATOM   3281 C  CA  . VAL A  1 410 ? -18.374 -23.193 -6.078  1.000 18.392 0 433  VAL A CA  1 ? 
ATOM   3282 C  C   . VAL A  1 410 ? -17.723 -21.853 -5.754  1.000 20.061 0 433  VAL A C   1 ? 
ATOM   3283 O  O   . VAL A  1 410 ? -18.210 -20.791 -6.184  1.000 19.465 0 433  VAL A O   1 ? 
ATOM   3284 C  CB  . VAL A  1 410 ? -17.712 -23.929 -7.257  1.000 19.633 0 433  VAL A CB  1 ? 
ATOM   3285 C  CG1 . VAL A  1 410 ? -18.152 -25.385 -7.372  1.000 19.411 0 433  VAL A CG1 1 ? 
ATOM   3286 C  CG2 . VAL A  1 410 ? -17.904 -23.218 -8.582  1.000 18.838 0 433  VAL A CG2 1 ? 
ATOM   3287 N  N   . LEU A  1 411 ? -16.565 -21.899 -5.065  1.000 18.454 0 434  LEU A N   1 ? 
ATOM   3288 C  CA  . LEU A  1 411 ? -16.004 -20.673 -4.521  1.000 19.453 0 434  LEU A CA  1 ? 
ATOM   3289 C  C   . LEU A  1 411 ? -14.948 -20.123 -5.484  1.000 18.610 0 434  LEU A C   1 ? 
ATOM   3290 O  O   . LEU A  1 411 ? -14.003 -20.839 -5.804  1.000 19.905 0 434  LEU A O   1 ? 
ATOM   3291 C  CB  . LEU A  1 411 ? -15.398 -20.989 -3.141  1.000 19.171 0 434  LEU A CB  1 ? 
ATOM   3292 C  CG  . LEU A  1 411 ? -14.881 -19.787 -2.348  1.000 17.788 0 434  LEU A CG  1 ? 
ATOM   3293 C  CD1 . LEU A  1 411 ? -16.057 -18.907 -1.958  1.000 18.276 0 434  LEU A CD1 1 ? 
ATOM   3294 C  CD2 . LEU A  1 411 ? -14.141 -20.290 -1.094  1.000 18.844 0 434  LEU A CD2 1 ? 
ATOM   3295 N  N   . GLN A  1 412 ? -15.114 -18.864 -5.901  1.000 18.804 0 435  GLN A N   1 ? 
ATOM   3296 C  CA  . GLN A  1 412 ? -14.167 -18.176 -6.761  1.000 19.246 0 435  GLN A CA  1 ? 
ATOM   3297 C  C   . GLN A  1 412 ? -13.122 -17.434 -5.919  1.000 20.645 0 435  GLN A C   1 ? 
ATOM   3298 O  O   . GLN A  1 412 ? -13.460 -16.483 -5.207  1.000 21.789 0 435  GLN A O   1 ? 
ATOM   3299 C  CB  . GLN A  1 412 ? -14.871 -17.161 -7.655  1.000 19.291 0 435  GLN A CB  1 ? 
ATOM   3300 C  CG  . GLN A  1 412 ? -13.924 -16.607 -8.712  1.000 20.858 0 435  GLN A CG  1 ? 
ATOM   3301 C  CD  . GLN A  1 412 ? -14.598 -15.897 -9.861  1.000 24.099 0 435  GLN A CD  1 ? 
ATOM   3302 O  OE1 . GLN A  1 412 ? -15.815 -15.868 -9.938  1.000 23.063 0 435  GLN A OE1 1 ? 
ATOM   3303 N  NE2 . GLN A  1 412 ? -13.814 -15.272 -10.726 1.000 23.512 0 435  GLN A NE2 1 ? 
ATOM   3304 N  N   . ILE A  1 413 ? -11.868 -17.855 -6.064  1.000 17.884 0 436  ILE A N   1 ? 
ATOM   3305 C  CA  . ILE A  1 413 ? -10.743 -17.329 -5.300  1.000 17.841 0 436  ILE A CA  1 ? 
ATOM   3306 C  C   . ILE A  1 413 ? -9.771  -16.627 -6.254  1.000 20.794 0 436  ILE A C   1 ? 
ATOM   3307 O  O   . ILE A  1 413 ? -9.210  -17.257 -7.149  1.000 19.921 0 436  ILE A O   1 ? 
ATOM   3308 C  CB  . ILE A  1 413 ? -10.041 -18.480 -4.548  1.000 17.632 0 436  ILE A CB  1 ? 
ATOM   3309 C  CG1 . ILE A  1 413 ? -10.949 -19.203 -3.562  1.000 18.115 0 436  ILE A CG1 1 ? 
ATOM   3310 C  CG2 . ILE A  1 413 ? -8.785  -17.977 -3.864  1.000 21.230 0 436  ILE A CG2 1 ? 
ATOM   3311 C  CD1 . ILE A  1 413 ? -10.365 -20.480 -3.036  1.000 18.492 0 436  ILE A CD1 1 ? 
ATOM   3312 N  N   . LYS A  1 414 ? -9.619  -15.322 -6.065  1.000 19.191 0 437  LYS A N   1 ? 
ATOM   3313 C  CA  . LYS A  1 414 ? -8.941  -14.460 -7.008  1.000 21.265 0 437  LYS A CA  1 ? 
ATOM   3314 C  C   . LYS A  1 414 ? -8.353  -13.251 -6.286  1.000 22.604 0 437  LYS A C   1 ? 
ATOM   3315 O  O   . LYS A  1 414 ? -8.708  -12.991 -5.142  1.000 19.219 0 437  LYS A O   1 ? 
ATOM   3316 C  CB  . LYS A  1 414 ? -9.949  -13.958 -8.041  1.000 21.797 0 437  LYS A CB  1 ? 
ATOM   3317 C  CG  . LYS A  1 414 ? -10.976 -12.964 -7.542  1.000 23.243 0 437  LYS A CG  1 ? 
ATOM   3318 C  CD  . LYS A  1 414 ? -12.141 -12.768 -8.525  1.000 25.028 0 437  LYS A CD  1 ? 
ATOM   3319 C  CE  . LYS A  1 414 ? -12.964 -11.554 -8.178  1.000 30.185 0 437  LYS A CE  1 ? 
ATOM   3320 N  NZ  . LYS A  1 414 ? -14.158 -11.433 -9.054  1.000 32.095 0 437  LYS A NZ  1 ? 
ATOM   3321 N  N   A ARG A  1 415 ? -7.510  -12.498 -7.008  0.500 21.009 0 438  ARG A N   1 ? 
ATOM   3322 N  N   B ARG A  1 415 ? -7.463  -12.523 -6.983  0.500 22.348 0 438  ARG A N   1 ? 
ATOM   3323 C  CA  A ARG A  1 415 ? -7.036  -11.191 -6.590  0.500 20.838 0 438  ARG A CA  1 ? 
ATOM   3324 C  CA  B ARG A  1 415 ? -7.053  -11.186 -6.583  0.500 23.327 0 438  ARG A CA  1 ? 
ATOM   3325 C  C   A ARG A  1 415 ? -8.131  -10.153 -6.874  0.500 22.627 0 438  ARG A C   1 ? 
ATOM   3326 C  C   B ARG A  1 415 ? -8.192  -10.205 -6.861  0.500 24.164 0 438  ARG A C   1 ? 
ATOM   3327 O  O   A ARG A  1 415 ? -8.540  -9.943  -8.023  0.500 23.636 0 438  ARG A O   1 ? 
ATOM   3328 O  O   B ARG A  1 415 ? -8.665  -10.071 -7.994  0.500 25.908 0 438  ARG A O   1 ? 
ATOM   3329 C  CB  A ARG A  1 415 ? -5.701  -10.960 -7.312  0.500 19.991 0 438  ARG A CB  1 ? 
ATOM   3330 C  CB  B ARG A  1 415 ? -5.782  -10.773 -7.332  0.500 24.331 0 438  ARG A CB  1 ? 
ATOM   3331 C  CG  A ARG A  1 415 ? -5.082  -9.596  -7.092  0.500 18.666 0 438  ARG A CG  1 ? 
ATOM   3332 C  CG  B ARG A  1 415 ? -5.507  -9.281  -7.298  0.500 24.608 0 438  ARG A CG  1 ? 
ATOM   3333 C  CD  A ARG A  1 415 ? -4.460  -9.375  -5.725  0.500 16.034 0 438  ARG A CD  1 ? 
ATOM   3334 C  CD  B ARG A  1 415 ? -5.313  -8.755  -5.888  0.500 24.098 0 438  ARG A CD  1 ? 
ATOM   3335 N  NE  A ARG A  1 415 ? -3.875  -8.047  -5.747  0.500 17.415 0 438  ARG A NE  1 ? 
ATOM   3336 N  NE  B ARG A  1 415 ? -4.405  -7.618  -5.837  0.500 26.509 0 438  ARG A NE  1 ? 
ATOM   3337 C  CZ  A ARG A  1 415 ? -3.112  -7.517  -4.808  0.500 15.640 0 438  ARG A CZ  1 ? 
ATOM   3338 C  CZ  B ARG A  1 415 ? -4.547  -6.460  -6.480  0.500 26.299 0 438  ARG A CZ  1 ? 
ATOM   3339 N  NH1 A ARG A  1 415 ? -2.719  -8.241  -3.789  0.500 16.184 0 438  ARG A NH1 1 ? 
ATOM   3340 N  NH1 B ARG A  1 415 ? -5.691  -6.083  -7.030  0.500 18.467 0 438  ARG A NH1 1 ? 
ATOM   3341 N  NH2 A ARG A  1 415 ? -2.747  -6.262  -4.917  0.500 16.808 0 438  ARG A NH2 1 ? 
ATOM   3342 N  NH2 B ARG A  1 415 ? -3.525  -5.622  -6.470  0.500 30.277 0 438  ARG A NH2 1 ? 
ATOM   3343 N  N   . LEU A  1 416 ? -8.604  -9.504  -5.805  1.000 22.026 0 439  LEU A N   1 ? 
ATOM   3344 C  CA  . LEU A  1 416 ? -9.725  -8.613  -5.840  1.000 21.409 0 439  LEU A CA  1 ? 
ATOM   3345 C  C   . LEU A  1 416 ? -9.245  -7.241  -6.293  1.000 25.073 0 439  LEU A C   1 ? 
ATOM   3346 O  O   . LEU A  1 416 ? -8.104  -6.848  -6.066  1.000 25.173 0 439  LEU A O   1 ? 
ATOM   3347 C  CB  . LEU A  1 416 ? -10.328 -8.508  -4.449  1.000 20.521 0 439  LEU A CB  1 ? 
ATOM   3348 C  CG  . LEU A  1 416 ? -10.732 -9.835  -3.817  1.000 22.375 0 439  LEU A CG  1 ? 
ATOM   3349 C  CD1 . LEU A  1 416 ? -11.019 -9.631  -2.331  1.000 24.323 0 439  LEU A CD1 1 ? 
ATOM   3350 C  CD2 . LEU A  1 416 ? -11.939 -10.435 -4.518  1.000 23.113 0 439  LEU A CD2 1 ? 
ATOM   3351 N  N   . ASP A  1 417 ? -10.161 -6.529  -6.923  1.000 25.552 0 440  ASP A N   1 ? 
ATOM   3352 C  CA  . ASP A  1 417 ? -10.004 -5.120  -7.214  1.000 25.478 0 440  ASP A CA  1 ? 
ATOM   3353 C  C   . ASP A  1 417 ? -10.835 -4.359  -6.183  1.000 28.828 0 440  ASP A C   1 ? 
ATOM   3354 O  O   . ASP A  1 417 ? -12.009 -4.047  -6.414  1.000 28.631 0 440  ASP A O   1 ? 
ATOM   3355 C  CB  . ASP A  1 417 ? -10.475 -4.838  -8.647  1.000 30.280 0 440  ASP A CB  1 ? 
ATOM   3356 C  CG  . ASP A  1 417 ? -10.198 -3.424  -9.124  1.000 35.830 0 440  ASP A CG  1 ? 
ATOM   3357 O  OD1 . ASP A  1 417 ? -9.531  -2.667  -8.404  1.000 36.222 0 440  ASP A OD1 1 ? 
ATOM   3358 O  OD2 . ASP A  1 417 ? -10.614 -3.115  -10.236 1.000 37.779 0 440  ASP A OD2 1 ? 
ATOM   3359 N  N   . ASP A  1 418 ? -10.213 -4.027  -5.056  1.000 26.145 0 441  ASP A N   1 ? 
ATOM   3360 C  CA  . ASP A  1 418 ? -10.941 -3.380  -3.995  1.000 26.286 0 441  ASP A CA  1 ? 
ATOM   3361 C  C   . ASP A  1 418 ? -9.988  -2.504  -3.202  1.000 25.555 0 441  ASP A C   1 ? 
ATOM   3362 O  O   . ASP A  1 418 ? -9.259  -2.971  -2.331  1.000 23.892 0 441  ASP A O   1 ? 
ATOM   3363 C  CB  . ASP A  1 418 ? -11.699 -4.408  -3.158  1.000 26.230 0 441  ASP A CB  1 ? 
ATOM   3364 C  CG  . ASP A  1 418 ? -12.587 -3.763  -2.106  1.000 28.379 0 441  ASP A CG  1 ? 
ATOM   3365 O  OD1 . ASP A  1 418 ? -12.501 -2.523  -1.946  1.000 27.098 0 441  ASP A OD1 1 ? 
ATOM   3366 O  OD2 . ASP A  1 418 ? -13.344 -4.513  -1.443  1.000 25.411 0 441  ASP A OD2 1 ? 
ATOM   3367 N  N   . PRO A  1 419 ? -9.974  -1.186  -3.446  1.000 25.600 0 442  PRO A N   1 ? 
ATOM   3368 C  CA  . PRO A  1 419 ? -9.050  -0.318  -2.728  1.000 27.390 0 442  PRO A CA  1 ? 
ATOM   3369 C  C   . PRO A  1 419 ? -9.289  -0.219  -1.224  1.000 26.111 0 442  PRO A C   1 ? 
ATOM   3370 O  O   . PRO A  1 419 ? -8.401  0.225   -0.499  1.000 24.241 0 442  PRO A O   1 ? 
ATOM   3371 C  CB  . PRO A  1 419 ? -9.220  1.055   -3.409  1.000 29.872 0 442  PRO A CB  1 ? 
ATOM   3372 C  CG  . PRO A  1 419 ? -10.520 0.969   -4.132  1.000 31.662 0 442  PRO A CG  1 ? 
ATOM   3373 C  CD  . PRO A  1 419 ? -10.736 -0.488  -4.494  1.000 29.737 0 442  PRO A CD  1 ? 
ATOM   3374 N  N   . GLU A  1 420 ? -10.496 -0.598  -0.763  1.000 23.333 0 443  GLU A N   1 ? 
ATOM   3375 C  CA  . GLU A  1 420 ? -10.815 -0.548  0.647   1.000 21.989 0 443  GLU A CA  1 ? 
ATOM   3376 C  C   . GLU A  1 420 ? -9.988  -1.584  1.397   1.000 21.890 0 443  GLU A C   1 ? 
ATOM   3377 O  O   . GLU A  1 420 ? -9.910  -1.508  2.597   1.000 21.437 0 443  GLU A O   1 ? 
ATOM   3378 C  CB  . GLU A  1 420 ? -12.319 -0.728  0.907   1.000 23.501 0 443  GLU A CB  1 ? 
ATOM   3379 C  CG  . GLU A  1 420 ? -13.119 0.502   0.476   1.000 23.178 0 443  GLU A CG  1 ? 
ATOM   3380 C  CD  . GLU A  1 420 ? -14.624 0.498   0.668   1.000 27.219 0 443  GLU A CD  1 ? 
ATOM   3381 O  OE1 . GLU A  1 420 ? -15.222 1.590   0.602   1.000 25.459 0 443  GLU A OE1 1 ? 
ATOM   3382 O  OE2 . GLU A  1 420 ? -15.195 -0.597  0.815   1.000 25.776 0 443  GLU A OE2 1 ? 
ATOM   3383 N  N   . LEU A  1 421 ? -9.409  -2.571  0.701   1.000 19.589 0 444  LEU A N   1 ? 
ATOM   3384 C  CA  . LEU A  1 421 ? -8.631  -3.613  1.384   1.000 20.107 0 444  LEU A CA  1 ? 
ATOM   3385 C  C   . LEU A  1 421 ? -7.141  -3.276  1.462   1.000 20.792 0 444  LEU A C   1 ? 
ATOM   3386 O  O   . LEU A  1 421 ? -6.344  -4.143  1.806   1.000 19.337 0 444  LEU A O   1 ? 
ATOM   3387 C  CB  . LEU A  1 421 ? -8.844  -4.915  0.609   1.000 19.206 0 444  LEU A CB  1 ? 
ATOM   3388 C  CG  . LEU A  1 421 ? -10.304 -5.346  0.477   1.000 20.116 0 444  LEU A CG  1 ? 
ATOM   3389 C  CD1 . LEU A  1 421 ? -10.373 -6.642  -0.299  1.000 20.890 0 444  LEU A CD1 1 ? 
ATOM   3390 C  CD2 . LEU A  1 421 ? -10.970 -5.492  1.853   1.000 20.135 0 444  LEU A CD2 1 ? 
ATOM   3391 N  N   . VAL A  1 422 ? -6.768  -2.028  1.159   1.000 20.991 0 445  VAL A N   1 ? 
ATOM   3392 C  CA  . VAL A  1 422 ? -5.376  -1.611  1.135   1.000 21.092 0 445  VAL A CA  1 ? 
ATOM   3393 C  C   . VAL A  1 422 ? -5.208  -0.432  2.079   1.000 22.128 0 445  VAL A C   1 ? 
ATOM   3394 O  O   . VAL A  1 422 ? -6.098  0.408   2.152   1.000 21.177 0 445  VAL A O   1 ? 
ATOM   3395 C  CB  . VAL A  1 422 ? -4.958  -1.183  -0.282  1.000 26.664 0 445  VAL A CB  1 ? 
ATOM   3396 C  CG1 . VAL A  1 422 ? -3.467  -0.851  -0.388  1.000 25.770 0 445  VAL A CG1 1 ? 
ATOM   3397 C  CG2 . VAL A  1 422 ? -5.347  -2.245  -1.275  1.000 26.842 0 445  VAL A CG2 1 ? 
ATOM   3398 N  N   . ASN A  1 423 ? -4.062  -0.391  2.770   1.000 20.781 0 446  ASN A N   1 ? 
ATOM   3399 C  CA  . ASN A  1 423 ? -3.677  0.762   3.569   1.000 21.234 0 446  ASN A CA  1 ? 
ATOM   3400 C  C   . ASN A  1 423 ? -2.183  1.018   3.311   1.000 22.809 0 446  ASN A C   1 ? 
ATOM   3401 O  O   . ASN A  1 423 ? -1.336  0.292   3.797   1.000 21.836 0 446  ASN A O   1 ? 
ATOM   3402 C  CB  . ASN A  1 423 ? -4.059  0.580   5.038   1.000 21.882 0 446  ASN A CB  1 ? 
ATOM   3403 C  CG  . ASN A  1 423 ? -3.700  1.768   5.918   1.000 25.014 0 446  ASN A CG  1 ? 
ATOM   3404 O  OD1 . ASN A  1 423 ? -2.684  2.424   5.688   1.000 26.362 0 446  ASN A OD1 1 ? 
ATOM   3405 N  ND2 . ASN A  1 423 ? -4.518  2.039   6.920   1.000 23.874 0 446  ASN A ND2 1 ? 
ATOM   3406 N  N   . GLU A  1 424 ? -1.859  2.051   2.520   1.000 24.750 0 447  GLU A N   1 ? 
ATOM   3407 C  CA  . GLU A  1 424 ? -0.485  2.342   2.124   1.000 28.639 0 447  GLU A CA  1 ? 
ATOM   3408 C  C   . GLU A  1 424 ? 0.364   2.812   3.298   1.000 24.815 0 447  GLU A C   1 ? 
ATOM   3409 O  O   . GLU A  1 424 ? 1.541   2.481   3.329   1.000 26.292 0 447  GLU A O   1 ? 
ATOM   3410 C  CB  . GLU A  1 424 ? -0.407  3.365   0.983   1.000 30.596 0 447  GLU A CB  1 ? 
ATOM   3411 C  CG  . GLU A  1 424 ? -0.806  2.714   -0.325  1.000 38.007 0 447  GLU A CG  1 ? 
ATOM   3412 C  CD  . GLU A  1 424 ? -0.837  3.637   -1.534  1.000 51.370 0 447  GLU A CD  1 ? 
ATOM   3413 O  OE1 . GLU A  1 424 ? -0.877  4.888   -1.353  1.000 52.185 0 447  GLU A OE1 1 ? 
ATOM   3414 O  OE2 . GLU A  1 424 ? -0.782  3.104   -2.654  1.000 55.200 0 447  GLU A OE2 1 ? 
ATOM   3415 N  N   . LYS A  1 425 ? -0.250  3.403   4.319   1.000 22.975 0 448  LYS A N   1 ? 
ATOM   3416 C  CA  . LYS A  1 425 ? 0.503   3.913   5.447   1.000 25.001 0 448  LYS A CA  1 ? 
ATOM   3417 C  C   . LYS A  1 425 ? 0.876   2.792   6.416   1.000 23.279 0 448  LYS A C   1 ? 
ATOM   3418 O  O   . LYS A  1 425 ? 2.031   2.704   6.821   1.000 22.613 0 448  LYS A O   1 ? 
ATOM   3419 C  CB  . LYS A  1 425 ? -0.278  5.089   6.031   1.000 30.323 0 448  LYS A CB  1 ? 
ATOM   3420 C  CG  . LYS A  1 425 ? 0.498   5.929   7.023   1.000 35.554 0 448  LYS A CG  1 ? 
ATOM   3421 C  CD  . LYS A  1 425 ? 1.873   6.434   6.538   1.000 35.968 0 448  LYS A CD  1 ? 
ATOM   3422 C  CE  . LYS A  1 425 ? 2.652   7.108   7.652   1.000 35.373 0 448  LYS A CE  1 ? 
ATOM   3423 N  NZ  . LYS A  1 425 ? 4.101   7.221   7.324   1.000 38.416 0 448  LYS A NZ  1 ? 
ATOM   3424 N  N   A SER A  1 426 ? -0.123  1.957   6.767   0.500 21.682 0 449  SER A N   1 ? 
ATOM   3425 N  N   B SER A  1 426 ? -0.065  1.913   6.765   0.500 21.579 0 449  SER A N   1 ? 
ATOM   3426 C  CA  A SER A  1 426 ? 0.064   0.662   7.435   0.500 22.501 0 449  SER A CA  1 ? 
ATOM   3427 C  CA  B SER A  1 426 ? 0.286   0.726   7.543   0.500 21.641 0 449  SER A CA  1 ? 
ATOM   3428 C  C   A SER A  1 426 ? 1.022   -0.244  6.674   0.500 22.660 0 449  SER A C   1 ? 
ATOM   3429 C  C   B SER A  1 426 ? 0.916   -0.359  6.663   0.500 22.553 0 449  SER A C   1 ? 
ATOM   3430 O  O   A SER A  1 426 ? 1.720   -1.077  7.264   0.500 21.590 0 449  SER A O   1 ? 
ATOM   3431 O  O   B SER A  1 426 ? 1.342   -1.409  7.156   0.500 22.764 0 449  SER A O   1 ? 
ATOM   3432 C  CB  A SER A  1 426 ? -1.242  -0.084  7.570   0.500 20.953 0 449  SER A CB  1 ? 
ATOM   3433 C  CB  B SER A  1 426 ? -0.915  0.203   8.264   0.500 20.578 0 449  SER A CB  1 ? 
ATOM   3434 O  OG  A SER A  1 426 ? -2.096  0.555   8.492   0.500 22.715 0 449  SER A OG  1 ? 
ATOM   3435 O  OG  B SER A  1 426 ? -1.882  -0.206  7.332   0.500 18.054 0 449  SER A OG  1 ? 
ATOM   3436 N  N   . ASN A  1 427 ? 0.980   -0.108  5.349   1.000 21.943 0 450  ASN A N   1 ? 
ATOM   3437 C  CA  . ASN A  1 427 ? 1.764   -0.898  4.413   1.000 20.901 0 450  ASN A CA  1 ? 
ATOM   3438 C  C   . ASN A  1 427 ? 1.261   -2.338  4.353   1.000 21.354 0 450  ASN A C   1 ? 
ATOM   3439 O  O   . ASN A  1 427 ? 2.041   -3.272  4.467   1.000 21.853 0 450  ASN A O   1 ? 
ATOM   3440 C  CB  . ASN A  1 427 ? 3.272   -0.793  4.666   1.000 20.443 0 450  ASN A CB  1 ? 
ATOM   3441 C  CG  . ASN A  1 427 ? 4.043   -1.393  3.507   1.000 24.310 0 450  ASN A CG  1 ? 
ATOM   3442 O  OD1 . ASN A  1 427 ? 3.654   -1.248  2.350   1.000 24.020 0 450  ASN A OD1 1 ? 
ATOM   3443 N  ND2 . ASN A  1 427 ? 5.087   -2.149  3.804   1.000 24.942 0 450  ASN A ND2 1 ? 
ATOM   3444 N  N   . VAL A  1 428 ? -0.058  -2.510  4.215   1.000 20.655 0 451  VAL A N   1 ? 
ATOM   3445 C  CA  . VAL A  1 428 ? -0.652  -3.821  4.049   1.000 20.831 0 451  VAL A CA  1 ? 
ATOM   3446 C  C   . VAL A  1 428 ? -1.658  -3.785  2.913   1.000 21.903 0 451  VAL A C   1 ? 
ATOM   3447 O  O   . VAL A  1 428 ? -2.227  -2.741  2.579   1.000 21.312 0 451  VAL A O   1 ? 
ATOM   3448 C  CB  . VAL A  1 428 ? -1.365  -4.327  5.324   1.000 21.266 0 451  VAL A CB  1 ? 
ATOM   3449 C  CG1 . VAL A  1 428 ? -0.416  -4.561  6.469   1.000 22.666 0 451  VAL A CG1 1 ? 
ATOM   3450 C  CG2 . VAL A  1 428 ? -2.498  -3.403  5.753   1.000 23.728 0 451  VAL A CG2 1 ? 
ATOM   3451 N  N   . ASP A  1 429 ? -1.915  -4.976  2.354   1.000 20.742 0 452  ASP A N   1 ? 
ATOM   3452 C  CA  . ASP A  1 429 ? -2.734  -5.098  1.161   1.000 21.451 0 452  ASP A CA  1 ? 
ATOM   3453 C  C   . ASP A  1 429 ? -3.404  -6.451  1.239   1.000 20.440 0 452  ASP A C   1 ? 
ATOM   3454 O  O   . ASP A  1 429 ? -2.716  -7.436  1.088   1.000 20.360 0 452  ASP A O   1 ? 
ATOM   3455 C  CB  . ASP A  1 429 ? -1.862  -4.933  -0.090  1.000 26.693 0 452  ASP A CB  1 ? 
ATOM   3456 C  CG  . ASP A  1 429 ? -2.553  -5.172  -1.428  1.000 27.067 0 452  ASP A CG  1 ? 
ATOM   3457 O  OD1 . ASP A  1 429 ? -3.748  -5.559  -1.450  1.000 23.741 0 452  ASP A OD1 1 ? 
ATOM   3458 O  OD2 . ASP A  1 429 ? -1.883  -4.988  -2.436  1.000 25.618 0 452  ASP A OD2 1 ? 
ATOM   3459 N  N   . TYR A  1 430 ? -4.705  -6.458  1.552   1.000 19.190 0 453  TYR A N   1 ? 
ATOM   3460 C  CA  . TYR A  1 430 ? -5.449  -7.695  1.774   1.000 19.923 0 453  TYR A CA  1 ? 
ATOM   3461 C  C   . TYR A  1 430 ? -6.355  -8.031  0.589   1.000 20.705 0 453  TYR A C   1 ? 
ATOM   3462 O  O   . TYR A  1 430 ? -7.405  -8.653  0.761   1.000 19.506 0 453  TYR A O   1 ? 
ATOM   3463 C  CB  . TYR A  1 430 ? -6.185  -7.562  3.117   1.000 18.711 0 453  TYR A CB  1 ? 
ATOM   3464 C  CG  . TYR A  1 430 ? -5.259  -7.327  4.309   1.000 19.071 0 453  TYR A CG  1 ? 
ATOM   3465 C  CD1 . TYR A  1 430 ? -4.071  -8.029  4.461   1.000 20.480 0 453  TYR A CD1 1 ? 
ATOM   3466 C  CD2 . TYR A  1 430 ? -5.616  -6.486  5.349   1.000 19.904 0 453  TYR A CD2 1 ? 
ATOM   3467 C  CE1 . TYR A  1 430 ? -3.223  -7.825  5.547   1.000 20.060 0 453  TYR A CE1 1 ? 
ATOM   3468 C  CE2 . TYR A  1 430 ? -4.801  -6.303  6.457   1.000 20.325 0 453  TYR A CE2 1 ? 
ATOM   3469 C  CZ  . TYR A  1 430 ? -3.582  -6.953  6.555   1.000 19.200 0 453  TYR A CZ  1 ? 
ATOM   3470 O  OH  . TYR A  1 430 ? -2.839  -6.750  7.692   1.000 19.805 0 453  TYR A OH  1 ? 
ATOM   3471 N  N   . ARG A  1 431 ? -5.905  -7.712  -0.633  1.000 19.034 0 454  ARG A N   1 ? 
ATOM   3472 C  CA  . ARG A  1 431 ? -6.716  -7.958  -1.810  1.000 19.867 0 454  ARG A CA  1 ? 
ATOM   3473 C  C   . ARG A  1 431 ? -6.602  -9.373  -2.366  1.000 20.167 0 454  ARG A C   1 ? 
ATOM   3474 O  O   . ARG A  1 431 ? -7.381  -9.702  -3.268  1.000 22.309 0 454  ARG A O   1 ? 
ATOM   3475 C  CB  . ARG A  1 431 ? -6.357  -6.969  -2.924  1.000 21.071 0 454  ARG A CB  1 ? 
ATOM   3476 C  CG  . ARG A  1 431 ? -6.850  -5.566  -2.628  1.000 21.147 0 454  ARG A CG  1 ? 
ATOM   3477 C  CD  . ARG A  1 431 ? -6.504  -4.562  -3.717  1.000 22.397 0 454  ARG A CD  1 ? 
ATOM   3478 N  NE  . ARG A  1 431 ? -5.079  -4.322  -3.728  1.000 23.112 0 454  ARG A NE  1 ? 
ATOM   3479 C  CZ  . ARG A  1 431 ? -4.483  -3.338  -4.382  1.000 26.872 0 454  ARG A CZ  1 ? 
ATOM   3480 N  NH1 . ARG A  1 431 ? -5.174  -2.601  -5.235  1.000 30.511 0 454  ARG A NH1 1 ? 
ATOM   3481 N  NH2 . ARG A  1 431 ? -3.208  -3.097  -4.143  1.000 27.727 0 454  ARG A NH2 1 ? 
ATOM   3482 N  N   . ASN A  1 432 ? -5.726  -10.229 -1.835  1.000 20.188 0 455  ASN A N   1 ? 
ATOM   3483 C  CA  . ASN A  1 432 ? -5.723  -11.616 -2.288  1.000 20.631 0 455  ASN A CA  1 ? 
ATOM   3484 C  C   . ASN A  1 432 ? -6.797  -12.409 -1.546  1.000 21.941 0 455  ASN A C   1 ? 
ATOM   3485 O  O   . ASN A  1 432 ? -6.681  -12.622 -0.349  1.000 21.532 0 455  ASN A O   1 ? 
ATOM   3486 C  CB  . ASN A  1 432 ? -4.353  -12.262 -2.170  1.000 22.340 0 455  ASN A CB  1 ? 
ATOM   3487 C  CG  . ASN A  1 432 ? -3.434  -11.803 -3.283  1.000 25.220 0 455  ASN A CG  1 ? 
ATOM   3488 O  OD1 . ASN A  1 432 ? -2.622  -10.907 -3.058  1.000 24.367 0 455  ASN A OD1 1 ? 
ATOM   3489 N  ND2 . ASN A  1 432 ? -3.592  -12.385 -4.475  1.000 23.970 0 455  ASN A ND2 1 ? 
ATOM   3490 N  N   . GLY A  1 433 ? -7.853  -12.827 -2.265  1.000 20.359 0 456  GLY A N   1 ? 
ATOM   3491 C  CA  . GLY A  1 433 ? -8.868  -13.723 -1.739  1.000 17.436 0 456  GLY A CA  1 ? 
ATOM   3492 C  C   . GLY A  1 433 ? -8.307  -15.112 -1.454  1.000 17.598 0 456  GLY A C   1 ? 
ATOM   3493 O  O   . GLY A  1 433 ? -7.331  -15.561 -2.071  1.000 19.779 0 456  GLY A O   1 ? 
ATOM   3494 N  N   . GLY A  1 434 ? -8.953  -15.796 -0.518  1.000 16.613 0 457  GLY A N   1 ? 
ATOM   3495 C  CA  . GLY A  1 434 ? -8.551  -17.106 -0.075  1.000 17.036 0 457  GLY A CA  1 ? 
ATOM   3496 C  C   . GLY A  1 434 ? -9.629  -17.776 0.765   1.000 18.101 0 457  GLY A C   1 ? 
ATOM   3497 O  O   . GLY A  1 434 ? -10.717 -17.216 0.958   1.000 18.643 0 457  GLY A O   1 ? 
ATOM   3498 N  N   . ALA A  1 435 ? -9.293  -18.969 1.253   1.000 17.061 0 458  ALA A N   1 ? 
ATOM   3499 C  CA  . ALA A  1 435 ? -10.213 -19.856 1.933   1.000 18.536 0 458  ALA A CA  1 ? 
ATOM   3500 C  C   . ALA A  1 435 ? -9.431  -20.894 2.732   1.000 18.520 0 458  ALA A C   1 ? 
ATOM   3501 O  O   . ALA A  1 435 ? -8.426  -21.407 2.271   1.000 18.699 0 458  ALA A O   1 ? 
ATOM   3502 C  CB  . ALA A  1 435 ? -11.132 -20.511 0.931   1.000 18.461 0 458  ALA A CB  1 ? 
ATOM   3503 N  N   . THR A  1 436 ? -9.902  -21.205 3.922   1.000 16.470 0 459  THR A N   1 ? 
ATOM   3504 C  CA  . THR A  1 436 ? -9.309  -22.244 4.738   1.000 16.629 0 459  THR A CA  1 ? 
ATOM   3505 C  C   . THR A  1 436 ? -10.388 -23.036 5.463   1.000 17.619 0 459  THR A C   1 ? 
ATOM   3506 O  O   . THR A  1 436 ? -11.459 -22.515 5.815   1.000 18.381 0 459  THR A O   1 ? 
ATOM   3507 C  CB  . THR A  1 436 ? -8.183  -21.658 5.625   1.000 18.346 0 459  THR A CB  1 ? 
ATOM   3508 O  OG1 . THR A  1 436 ? -7.463  -22.779 6.143   1.000 18.103 0 459  THR A OG1 1 ? 
ATOM   3509 C  CG2 . THR A  1 436 ? -8.665  -20.815 6.795   1.000 18.869 0 459  THR A CG2 1 ? 
ATOM   3510 N  N   . TRP A  1 437 ? -10.060 -24.314 5.723   1.000 18.476 0 460  TRP A N   1 ? 
ATOM   3511 C  CA  . TRP A  1 437 ? -10.974 -25.324 6.210   1.000 18.606 0 460  TRP A CA  1 ? 
ATOM   3512 C  C   . TRP A  1 437 ? -10.221 -26.322 7.076   1.000 17.852 0 460  TRP A C   1 ? 
ATOM   3513 O  O   . TRP A  1 437 ? -9.096  -26.716 6.733   1.000 17.504 0 460  TRP A O   1 ? 
ATOM   3514 C  CB  . TRP A  1 437 ? -11.625 -26.033 5.010   1.000 19.001 0 460  TRP A CB  1 ? 
ATOM   3515 C  CG  . TRP A  1 437 ? -12.642 -27.074 5.361   1.000 18.150 0 460  TRP A CG  1 ? 
ATOM   3516 C  CD1 . TRP A  1 437 ? -13.967 -26.900 5.692   1.000 18.699 0 460  TRP A CD1 1 ? 
ATOM   3517 C  CD2 . TRP A  1 437 ? -12.439 -28.504 5.260   1.000 18.219 0 460  TRP A CD2 1 ? 
ATOM   3518 N  NE1 . TRP A  1 437 ? -14.568 -28.125 5.889   1.000 18.856 0 460  TRP A NE1 1 ? 
ATOM   3519 C  CE2 . TRP A  1 437 ? -13.667 -29.117 5.599   1.000 19.385 0 460  TRP A CE2 1 ? 
ATOM   3520 C  CE3 . TRP A  1 437 ? -11.345 -29.299 4.925   1.000 18.815 0 460  TRP A CE3 1 ? 
ATOM   3521 C  CZ2 . TRP A  1 437 ? -13.819 -30.490 5.604   1.000 20.701 0 460  TRP A CZ2 1 ? 
ATOM   3522 C  CZ3 . TRP A  1 437 ? -11.515 -30.663 4.887   1.000 21.850 0 460  TRP A CZ3 1 ? 
ATOM   3523 C  CH2 . TRP A  1 437 ? -12.732 -31.246 5.226   1.000 19.809 0 460  TRP A CH2 1 ? 
ATOM   3524 N  N   . ASN A  1 438 ? -10.868 -26.668 8.196   1.000 18.746 0 461  ASN A N   1 ? 
ATOM   3525 C  CA  . ASN A  1 438 ? -10.331 -27.498 9.261   1.000 18.097 0 461  ASN A CA  1 ? 
ATOM   3526 C  C   . ASN A  1 438 ? -10.663 -28.971 8.996   1.000 19.788 0 461  ASN A C   1 ? 
ATOM   3527 O  O   . ASN A  1 438 ? -11.742 -29.284 8.509   1.000 19.630 0 461  ASN A O   1 ? 
ATOM   3528 C  CB  . ASN A  1 438 ? -10.911 -27.075 10.610  1.000 19.357 0 461  ASN A CB  1 ? 
ATOM   3529 C  CG  . ASN A  1 438 ? -10.544 -27.911 11.811  1.000 18.559 0 461  ASN A CG  1 ? 
ATOM   3530 O  OD1 . ASN A  1 438 ? -11.433 -28.396 12.484  1.000 19.984 0 461  ASN A OD1 1 ? 
ATOM   3531 N  ND2 . ASN A  1 438 ? -9.279  -27.954 12.179  1.000 19.548 0 461  ASN A ND2 1 ? 
ATOM   3532 N  N   . PHE A  1 439 ? -9.790  -29.858 9.507   1.000 18.617 0 462  PHE A N   1 ? 
ATOM   3533 C  CA  . PHE A  1 439 ? -10.090 -31.273 9.574   1.000 19.820 0 462  PHE A CA  1 ? 
ATOM   3534 C  C   . PHE A  1 439 ? -9.359  -31.880 10.760  1.000 19.923 0 462  PHE A C   1 ? 
ATOM   3535 O  O   . PHE A  1 439 ? -8.391  -31.305 11.239  1.000 19.921 0 462  PHE A O   1 ? 
ATOM   3536 C  CB  . PHE A  1 439 ? -9.729  -31.960 8.244   1.000 20.277 0 462  PHE A CB  1 ? 
ATOM   3537 C  CG  . PHE A  1 439 ? -8.304  -31.800 7.783   1.000 19.254 0 462  PHE A CG  1 ? 
ATOM   3538 C  CD1 . PHE A  1 439 ? -7.279  -32.578 8.301   1.000 20.213 0 462  PHE A CD1 1 ? 
ATOM   3539 C  CD2 . PHE A  1 439 ? -7.981  -30.800 6.886   1.000 18.137 0 462  PHE A CD2 1 ? 
ATOM   3540 C  CE1 . PHE A  1 439 ? -5.965  -32.353 7.908   1.000 19.432 0 462  PHE A CE1 1 ? 
ATOM   3541 C  CE2 . PHE A  1 439 ? -6.677  -30.607 6.475   1.000 19.133 0 462  PHE A CE2 1 ? 
ATOM   3542 C  CZ  . PHE A  1 439 ? -5.674  -31.397 6.974   1.000 19.416 0 462  PHE A CZ  1 ? 
ATOM   3543 N  N   . PRO A  1 440 ? -9.792  -33.046 11.284  1.000 21.441 0 463  PRO A N   1 ? 
ATOM   3544 C  CA  . PRO A  1 440 ? -9.105  -33.666 12.414  1.000 20.595 0 463  PRO A CA  1 ? 
ATOM   3545 C  C   . PRO A  1 440 ? -7.611  -33.825 12.156  1.000 22.292 0 463  PRO A C   1 ? 
ATOM   3546 O  O   . PRO A  1 440 ? -7.149  -34.182 11.081  1.000 23.493 0 463  PRO A O   1 ? 
ATOM   3547 C  CB  . PRO A  1 440 ? -9.838  -34.998 12.571  1.000 22.205 0 463  PRO A CB  1 ? 
ATOM   3548 C  CG  . PRO A  1 440 ? -11.210 -34.721 12.049  1.000 22.830 0 463  PRO A CG  1 ? 
ATOM   3549 C  CD  . PRO A  1 440 ? -10.984 -33.801 10.875  1.000 23.306 0 463  PRO A CD  1 ? 
ATOM   3550 N  N   . ASN A  1 441 ? -6.817  -33.503 13.167  1.000 21.998 0 464  ASN A N   1 ? 
ATOM   3551 C  CA  . ASN A  1 441 ? -5.387  -33.514 13.062  1.000 20.255 0 464  ASN A CA  1 ? 
ATOM   3552 C  C   . ASN A  1 441 ? -4.840  -34.908 12.696  1.000 20.393 0 464  ASN A C   1 ? 
ATOM   3553 O  O   . ASN A  1 441 ? -5.342  -35.907 13.197  1.000 24.664 0 464  ASN A O   1 ? 
ATOM   3554 C  CB  . ASN A  1 441 ? -4.803  -33.116 14.403  1.000 21.484 0 464  ASN A CB  1 ? 
ATOM   3555 C  CG  . ASN A  1 441 ? -3.296  -33.159 14.419  1.000 21.944 0 464  ASN A CG  1 ? 
ATOM   3556 O  OD1 . ASN A  1 441 ? -2.624  -32.293 13.873  1.000 22.975 0 464  ASN A OD1 1 ? 
ATOM   3557 N  ND2 . ASN A  1 441 ? -2.767  -34.210 15.017  1.000 24.009 0 464  ASN A ND2 1 ? 
ATOM   3558 N  N   . GLY A  1 442 ? -3.819  -34.923 11.850  1.000 23.817 0 465  GLY A N   1 ? 
ATOM   3559 C  CA  . GLY A  1 442 ? -3.058  -36.145 11.567  1.000 24.109 0 465  GLY A CA  1 ? 
ATOM   3560 C  C   . GLY A  1 442 ? -1.608  -35.830 11.251  1.000 22.389 0 465  GLY A C   1 ? 
ATOM   3561 O  O   . GLY A  1 442 ? -1.301  -34.872 10.521  1.000 22.781 0 465  GLY A O   1 ? 
ATOM   3562 N  N   . THR A  1 443 ? -0.683  -36.666 11.793  1.000 25.170 0 466  THR A N   1 ? 
ATOM   3563 C  CA  . THR A  1 443 ? 0.701   -36.686 11.336  1.000 27.063 0 466  THR A CA  1 ? 
ATOM   3564 C  C   . THR A  1 443 ? 0.852   -37.418 10.005  1.000 24.004 0 466  THR A C   1 ? 
ATOM   3565 O  O   . THR A  1 443 ? 1.816   -37.171 9.278   1.000 27.029 0 466  THR A O   1 ? 
ATOM   3566 C  CB  . THR A  1 443 ? 1.622   -37.389 12.344  1.000 28.989 0 466  THR A CB  1 ? 
ATOM   3567 O  OG1 . THR A  1 443 ? 0.923   -38.540 12.829  1.000 30.205 0 466  THR A OG1 1 ? 
ATOM   3568 C  CG2 . THR A  1 443 ? 1.978   -36.434 13.466  1.000 36.986 0 466  THR A CG2 1 ? 
ATOM   3569 N  N   A THR A  1 444 ? -0.104  -38.304 9.706   0.500 26.466 0 467  THR A N   1 ? 
ATOM   3570 N  N   B THR A  1 444 ? -0.140  -38.260 9.688   0.500 25.345 0 467  THR A N   1 ? 
ATOM   3571 C  CA  A THR A  1 444 ? -0.276  -38.759 8.330   0.500 27.273 0 467  THR A CA  1 ? 
ATOM   3572 C  CA  B THR A  1 444 ? -0.260  -38.847 8.353   0.500 25.236 0 467  THR A CA  1 ? 
ATOM   3573 C  C   A THR A  1 444 ? -1.730  -38.652 7.914   0.500 24.221 0 467  THR A C   1 ? 
ATOM   3574 C  C   B THR A  1 444 ? -1.713  -38.749 7.894   0.500 23.304 0 467  THR A C   1 ? 
ATOM   3575 O  O   A THR A  1 444 ? -2.643  -38.816 8.719   0.500 24.808 0 467  THR A O   1 ? 
ATOM   3576 O  O   B THR A  1 444 ? -2.632  -38.985 8.669   0.500 24.687 0 467  THR A O   1 ? 
ATOM   3577 C  CB  A THR A  1 444 ? 0.143   -40.209 8.078   0.500 26.770 0 467  THR A CB  1 ? 
ATOM   3578 C  CB  B THR A  1 444 ? 0.279   -40.283 8.344   0.500 23.894 0 467  THR A CB  1 ? 
ATOM   3579 O  OG1 A THR A  1 444 ? -0.859  -41.064 8.637   0.500 33.141 0 467  THR A OG1 1 ? 
ATOM   3580 O  OG1 B THR A  1 444 ? -0.057  -40.956 7.125   0.500 20.338 0 467  THR A OG1 1 ? 
ATOM   3581 C  CG2 A THR A  1 444 ? 1.525   -40.494 8.609   0.500 24.873 0 467  THR A CG2 1 ? 
ATOM   3582 C  CG2 B THR A  1 444 ? -0.255  -41.069 9.518   0.500 26.858 0 467  THR A CG2 1 ? 
ATOM   3583 N  N   . GLY A  1 445 ? -1.925  -38.348 6.637   1.000 24.450 0 468  GLY A N   1 ? 
ATOM   3584 C  CA  . GLY A  1 445 ? -3.277  -38.322 6.109   1.000 24.424 0 468  GLY A CA  1 ? 
ATOM   3585 C  C   . GLY A  1 445 ? -3.320  -38.127 4.598   1.000 21.570 0 468  GLY A C   1 ? 
ATOM   3586 O  O   . GLY A  1 445 ? -2.301  -38.025 3.936   1.000 24.295 0 468  GLY A O   1 ? 
ATOM   3587 N  N   . LEU A  1 446 ? -4.554  -37.999 4.102   1.000 22.421 0 469  LEU A N   1 ? 
ATOM   3588 C  CA  . LEU A  1 446 ? -4.854  -37.829 2.701   1.000 22.439 0 469  LEU A CA  1 ? 
ATOM   3589 C  C   . LEU A  1 446 ? -5.917  -36.745 2.581   1.000 22.286 0 469  LEU A C   1 ? 
ATOM   3590 O  O   . LEU A  1 446 ? -6.992  -36.879 3.157   1.000 22.960 0 469  LEU A O   1 ? 
ATOM   3591 C  CB  . LEU A  1 446 ? -5.397  -39.137 2.139   1.000 23.961 0 469  LEU A CB  1 ? 
ATOM   3592 C  CG  . LEU A  1 446 ? -5.766  -39.092 0.648   1.000 26.796 0 469  LEU A CG  1 ? 
ATOM   3593 C  CD1 . LEU A  1 446 ? -4.552  -38.783 -0.211  1.000 25.978 0 469  LEU A CD1 1 ? 
ATOM   3594 C  CD2 . LEU A  1 446 ? -6.454  -40.383 0.217   1.000 27.534 0 469  LEU A CD2 1 ? 
ATOM   3595 N  N   . VAL A  1 447 ? -5.575  -35.654 1.907   1.000 23.219 0 470  VAL A N   1 ? 
ATOM   3596 C  CA  . VAL A  1 447 ? -6.571  -34.632 1.609   1.000 23.384 0 470  VAL A CA  1 ? 
ATOM   3597 C  C   . VAL A  1 447 ? -6.726  -34.493 0.097   1.000 21.180 0 470  VAL A C   1 ? 
ATOM   3598 O  O   . VAL A  1 447 ? -5.735  -34.403 -0.631  1.000 22.553 0 470  VAL A O   1 ? 
ATOM   3599 C  CB  . VAL A  1 447 ? -6.176  -33.285 2.251   1.000 24.638 0 470  VAL A CB  1 ? 
ATOM   3600 C  CG1 . VAL A  1 447 ? -7.023  -32.133 1.727   1.000 28.482 0 470  VAL A CG1 1 ? 
ATOM   3601 C  CG2 . VAL A  1 447 ? -6.249  -33.359 3.755   1.000 28.616 0 470  VAL A CG2 1 ? 
ATOM   3602 N  N   . LYS A  1 448 ? -7.987  -34.454 -0.374  1.000 23.034 0 471  LYS A N   1 ? 
ATOM   3603 C  CA  . LYS A  1 448 ? -8.278  -34.246 -1.785  1.000 22.291 0 471  LYS A CA  1 ? 
ATOM   3604 C  C   . LYS A  1 448 ? -9.124  -33.002 -1.967  1.000 21.298 0 471  LYS A C   1 ? 
ATOM   3605 O  O   . LYS A  1 448 ? -10.042 -32.820 -1.193  1.000 21.301 0 471  LYS A O   1 ? 
ATOM   3606 C  CB  . LYS A  1 448 ? -9.035  -35.442 -2.345  1.000 27.826 0 471  LYS A CB  1 ? 
ATOM   3607 C  CG  . LYS A  1 448 ? -8.341  -36.787 -2.224  1.000 38.315 0 471  LYS A CG  1 ? 
ATOM   3608 C  CD  . LYS A  1 448 ? -8.843  -37.807 -3.250  1.000 48.952 0 471  LYS A CD  1 ? 
ATOM   3609 C  CE  . LYS A  1 448 ? -10.255 -38.295 -3.021  1.000 54.908 0 471  LYS A CE  1 ? 
ATOM   3610 N  NZ  . LYS A  1 448 ? -10.250 -39.709 -2.583  1.000 61.557 0 471  LYS A NZ  1 ? 
ATOM   3611 N  N   . PHE A  1 449 ? -8.843  -32.191 -3.000  1.000 19.615 0 472  PHE A N   1 ? 
ATOM   3612 C  CA  . PHE A  1 449 ? -9.717  -31.107 -3.387  1.000 20.359 0 472  PHE A CA  1 ? 
ATOM   3613 C  C   . PHE A  1 449 ? -9.866  -31.018 -4.907  1.000 22.381 0 472  PHE A C   1 ? 
ATOM   3614 O  O   . PHE A  1 449 ? -9.020  -31.488 -5.691  1.000 22.943 0 472  PHE A O   1 ? 
ATOM   3615 C  CB  . PHE A  1 449 ? -9.191  -29.777 -2.830  1.000 20.602 0 472  PHE A CB  1 ? 
ATOM   3616 C  CG  . PHE A  1 449 ? -7.845  -29.319 -3.344  1.000 20.398 0 472  PHE A CG  1 ? 
ATOM   3617 C  CD1 . PHE A  1 449 ? -6.673  -29.769 -2.754  1.000 20.607 0 472  PHE A CD1 1 ? 
ATOM   3618 C  CD2 . PHE A  1 449 ? -7.747  -28.406 -4.383  1.000 20.865 0 472  PHE A CD2 1 ? 
ATOM   3619 C  CE1 . PHE A  1 449 ? -5.435  -29.366 -3.229  1.000 20.850 0 472  PHE A CE1 1 ? 
ATOM   3620 C  CE2 . PHE A  1 449 ? -6.509  -27.998 -4.861  1.000 21.219 0 472  PHE A CE2 1 ? 
ATOM   3621 C  CZ  . PHE A  1 449 ? -5.351  -28.486 -4.281  1.000 21.896 0 472  PHE A CZ  1 ? 
ATOM   3622 N  N   . ARG A  1 450 ? -10.924 -30.332 -5.304  1.000 19.877 0 473  ARG A N   1 ? 
ATOM   3623 C  CA  . ARG A  1 450 ? -11.350 -30.242 -6.689  1.000 21.872 0 473  ARG A CA  1 ? 
ATOM   3624 C  C   . ARG A  1 450 ? -11.434 -28.771 -7.065  1.000 22.307 0 473  ARG A C   1 ? 
ATOM   3625 O  O   . ARG A  1 450 ? -12.117 -27.980 -6.395  1.000 21.250 0 473  ARG A O   1 ? 
ATOM   3626 C  CB  . ARG A  1 450 ? -12.708 -30.935 -6.819  1.000 24.584 0 473  ARG A CB  1 ? 
ATOM   3627 C  CG  . ARG A  1 450 ? -13.213 -31.152 -8.235  1.000 28.510 0 473  ARG A CG  1 ? 
ATOM   3628 C  CD  . ARG A  1 450 ? -14.360 -32.176 -8.143  1.000 28.284 0 473  ARG A CD  1 ? 
ATOM   3629 N  NE  . ARG A  1 450 ? -14.848 -32.533 -9.466  1.000 29.274 0 473  ARG A NE  1 ? 
ATOM   3630 C  CZ  . ARG A  1 450 ? -15.716 -31.850 -10.198 1.000 29.733 0 473  ARG A CZ  1 ? 
ATOM   3631 N  NH1 . ARG A  1 450 ? -16.350 -30.789 -9.730  1.000 25.613 0 473  ARG A NH1 1 ? 
ATOM   3632 N  NH2 . ARG A  1 450 ? -15.981 -32.260 -11.426 1.000 31.155 0 473  ARG A NH2 1 ? 
ATOM   3633 N  N   . PHE A  1 451 ? -10.768 -28.442 -8.159  1.000 21.069 0 474  PHE A N   1 ? 
ATOM   3634 C  CA  . PHE A  1 451 ? -10.614 -27.066 -8.585  1.000 19.878 0 474  PHE A CA  1 ? 
ATOM   3635 C  C   . PHE A  1 451 ? -10.666 -26.967 -10.106 1.000 21.515 0 474  PHE A C   1 ? 
ATOM   3636 O  O   . PHE A  1 451 ? -10.469 -27.960 -10.834 1.000 22.941 0 474  PHE A O   1 ? 
ATOM   3637 C  CB  . PHE A  1 451 ? -9.285  -26.458 -8.103  1.000 22.049 0 474  PHE A CB  1 ? 
ATOM   3638 C  CG  . PHE A  1 451 ? -8.078  -26.848 -8.917  1.000 23.001 0 474  PHE A CG  1 ? 
ATOM   3639 C  CD1 . PHE A  1 451 ? -7.536  -28.113 -8.810  1.000 25.422 0 474  PHE A CD1 1 ? 
ATOM   3640 C  CD2 . PHE A  1 451 ? -7.575  -26.003 -9.886  1.000 27.136 0 474  PHE A CD2 1 ? 
ATOM   3641 C  CE1 . PHE A  1 451 ? -6.462  -28.501 -9.604  1.000 25.077 0 474  PHE A CE1 1 ? 
ATOM   3642 C  CE2 . PHE A  1 451 ? -6.496  -26.391 -10.666 1.000 27.233 0 474  PHE A CE2 1 ? 
ATOM   3643 C  CZ  . PHE A  1 451 ? -5.942  -27.639 -10.515 1.000 24.840 0 474  PHE A CZ  1 ? 
ATOM   3644 N  N   . ARG A  1 452 ? -10.829 -25.727 -10.552 1.000 19.760 0 475  ARG A N   1 ? 
ATOM   3645 C  CA  . ARG A  1 452 ? -10.965 -25.436 -11.977 1.000 21.970 0 475  ARG A CA  1 ? 
ATOM   3646 C  C   . ARG A  1 452 ? -10.540 -24.002 -12.217 1.000 22.794 0 475  ARG A C   1 ? 
ATOM   3647 O  O   . ARG A  1 452 ? -10.848 -23.115 -11.400 1.000 24.205 0 475  ARG A O   1 ? 
ATOM   3648 C  CB  . ARG A  1 452 ? -12.413 -25.622 -12.417 1.000 24.398 0 475  ARG A CB  1 ? 
ATOM   3649 C  CG  . ARG A  1 452 ? -12.669 -25.213 -13.853 1.000 26.708 0 475  ARG A CG  1 ? 
ATOM   3650 C  CD  . ARG A  1 452 ? -14.088 -25.589 -14.185 1.000 29.277 0 475  ARG A CD  1 ? 
ATOM   3651 N  NE  . ARG A  1 452 ? -14.370 -25.169 -15.538 1.000 29.408 0 475  ARG A NE  1 ? 
ATOM   3652 C  CZ  . ARG A  1 452 ? -15.180 -25.820 -16.350 1.000 30.065 0 475  ARG A CZ  1 ? 
ATOM   3653 N  NH1 . ARG A  1 452 ? -15.844 -26.870 -15.913 1.000 27.831 0 475  ARG A NH1 1 ? 
ATOM   3654 N  NH2 . ARG A  1 452 ? -15.371 -25.376 -17.578 1.000 32.434 0 475  ARG A NH2 1 ? 
ATOM   3655 N  N   . VAL A  1 453 ? -9.866  -23.776 -13.354 1.000 21.525 0 476  VAL A N   1 ? 
ATOM   3656 C  CA  . VAL A  1 453 ? -9.467  -22.431 -13.754 1.000 22.790 0 476  VAL A CA  1 ? 
ATOM   3657 C  C   . VAL A  1 453 ? -10.663 -21.662 -14.288 1.000 24.353 0 476  VAL A C   1 ? 
ATOM   3658 O  O   . VAL A  1 453 ? -11.371 -22.173 -15.142 1.000 23.403 0 476  VAL A O   1 ? 
ATOM   3659 C  CB  . VAL A  1 453 ? -8.332  -22.441 -14.802 1.000 24.650 0 476  VAL A CB  1 ? 
ATOM   3660 C  CG1 . VAL A  1 453 ? -7.946  -21.027 -15.200 1.000 26.594 0 476  VAL A CG1 1 ? 
ATOM   3661 C  CG2 . VAL A  1 453 ? -7.133  -23.207 -14.285 1.000 23.123 0 476  VAL A CG2 1 ? 
ATOM   3662 N  N   . VAL A  1 454 ? -10.872 -20.430 -13.784 1.000 22.297 0 477  VAL A N   1 ? 
ATOM   3663 C  CA  . VAL A  1 454 ? -11.947 -19.571 -14.258 1.000 24.252 0 477  VAL A CA  1 ? 
ATOM   3664 C  C   . VAL A  1 454 ? -11.611 -19.086 -15.665 1.000 26.852 0 477  VAL A C   1 ? 
ATOM   3665 O  O   . VAL A  1 454 ? -10.489 -18.665 -15.968 1.000 24.633 0 477  VAL A O   1 ? 
ATOM   3666 C  CB  . VAL A  1 454 ? -12.215 -18.361 -13.338 1.000 24.450 0 477  VAL A CB  1 ? 
ATOM   3667 C  CG1 . VAL A  1 454 ? -13.282 -17.447 -13.938 1.000 25.264 0 477  VAL A CG1 1 ? 
ATOM   3668 C  CG2 . VAL A  1 454 ? -12.606 -18.757 -11.931 1.000 22.886 0 477  VAL A CG2 1 ? 
ATOM   3669 N  N   . ASP A  1 455 ? -12.615 -19.146 -16.538 1.000 28.015 0 478  ASP A N   1 ? 
ATOM   3670 C  CA  . ASP A  1 455 ? -12.416 -18.802 -17.932 1.000 34.087 0 478  ASP A CA  1 ? 
ATOM   3671 C  C   . ASP A  1 455 ? -12.431 -17.285 -18.039 1.000 34.996 0 478  ASP A C   1 ? 
ATOM   3672 O  O   . ASP A  1 455 ? -13.444 -16.717 -18.400 1.000 47.148 0 478  ASP A O   1 ? 
ATOM   3673 C  CB  . ASP A  1 455 ? -13.516 -19.457 -18.780 1.000 38.914 0 478  ASP A CB  1 ? 
ATOM   3674 C  CG  . ASP A  1 455 ? -13.320 -19.316 -20.283 1.000 47.489 0 478  ASP A CG  1 ? 
ATOM   3675 O  OD1 . ASP A  1 455 ? -12.211 -18.916 -20.699 1.000 43.641 0 478  ASP A OD1 1 ? 
ATOM   3676 O  OD2 . ASP A  1 455 ? -14.295 -19.576 -21.024 1.000 53.890 0 478  ASP A OD2 1 ? 
ATOM   3677 N  N   . GLY A  1 456 ? -11.321 -16.625 -17.742 1.000 30.518 0 479  GLY A N   1 ? 
ATOM   3678 C  CA  . GLY A  1 456 ? -11.256 -15.169 -17.772 1.000 28.670 0 479  GLY A CA  1 ? 
ATOM   3679 C  C   . GLY A  1 456 ? -9.809  -14.700 -17.815 1.000 28.331 0 479  GLY A C   1 ? 
ATOM   3680 O  O   . GLY A  1 456 ? -8.910  -15.523 -17.822 1.000 32.210 0 479  GLY A O   1 ? 
ATOM   3681 N  N   . GLU A  1 457 ? -9.592  -13.392 -17.899 1.000 28.254 0 480  GLU A N   1 ? 
ATOM   3682 C  CA  . GLU A  1 457 ? -8.250  -12.834 -17.948 1.000 34.827 0 480  GLU A CA  1 ? 
ATOM   3683 C  C   . GLU A  1 457 ? -7.506  -13.077 -16.630 1.000 31.054 0 480  GLU A C   1 ? 
ATOM   3684 O  O   . GLU A  1 457 ? -8.043  -12.825 -15.554 1.000 28.429 0 480  GLU A O   1 ? 
ATOM   3685 C  CB  . GLU A  1 457 ? -8.318  -11.340 -18.281 1.000 38.264 0 480  GLU A CB  1 ? 
ATOM   3686 C  CG  . GLU A  1 457 ? -8.667  -11.094 -19.737 1.000 54.402 0 480  GLU A CG  1 ? 
ATOM   3687 C  CD  . GLU A  1 457 ? -8.304  -9.716  -20.268 1.000 74.146 0 480  GLU A CD  1 ? 
ATOM   3688 O  OE1 . GLU A  1 457 ? -7.152  -9.278  -20.035 1.000 76.200 0 480  GLU A OE1 1 ? 
ATOM   3689 O  OE2 . GLU A  1 457 ? -9.165  -9.091  -20.936 1.000 84.363 0 480  GLU A OE2 1 ? 
ATOM   3690 N  N   . GLN A  1 458 ? -6.244  -13.500 -16.743 1.000 28.893 0 481  GLN A N   1 ? 
ATOM   3691 C  CA  . GLN A  1 458 ? -5.390  -13.807 -15.600 1.000 27.266 0 481  GLN A CA  1 ? 
ATOM   3692 C  C   . GLN A  1 458 ? -4.103  -12.995 -15.686 1.000 33.470 0 481  GLN A C   1 ? 
ATOM   3693 O  O   . GLN A  1 458 ? -3.634  -12.700 -16.779 1.000 30.226 0 481  GLN A O   1 ? 
ATOM   3694 C  CB  . GLN A  1 458 ? -4.990  -15.278 -15.598 1.000 27.992 0 481  GLN A CB  1 ? 
ATOM   3695 C  CG  . GLN A  1 458 ? -6.137  -16.262 -15.694 1.000 27.969 0 481  GLN A CG  1 ? 
ATOM   3696 C  CD  . GLN A  1 458 ? -6.931  -16.389 -14.417 1.000 28.190 0 481  GLN A CD  1 ? 
ATOM   3697 O  OE1 . GLN A  1 458 ? -6.715  -15.669 -13.441 1.000 22.320 0 481  GLN A OE1 1 ? 
ATOM   3698 N  NE2 . GLN A  1 458 ? -7.850  -17.340 -14.430 1.000 27.105 0 481  GLN A NE2 1 ? 
ATOM   3699 N  N   . ALA A  1 459 ? -3.506  -12.696 -14.531 1.000 29.110 0 482  ALA A N   1 ? 
ATOM   3700 C  CA  . ALA A  1 459 ? -2.250  -11.980 -14.469 1.000 26.324 0 482  ALA A CA  1 ? 
ATOM   3701 C  C   . ALA A  1 459 ? -1.121  -12.970 -14.574 1.000 25.869 0 482  ALA A C   1 ? 
ATOM   3702 O  O   . ALA A  1 459 ? -1.308  -14.174 -14.409 1.000 24.006 0 482  ALA A O   1 ? 
ATOM   3703 C  CB  . ALA A  1 459 ? -2.160  -11.183 -13.188 1.000 31.403 0 482  ALA A CB  1 ? 
ATOM   3704 N  N   . ASP A  1 460 ? 0.101   -12.442 -14.751 1.000 28.645 0 483  ASP A N   1 ? 
ATOM   3705 C  CA  . ASP A  1 460 ? 1.251   -13.307 -14.925 1.000 29.492 0 483  ASP A CA  1 ? 
ATOM   3706 C  C   . ASP A  1 460 ? 1.504   -14.188 -13.706 1.000 29.033 0 483  ASP A C   1 ? 
ATOM   3707 O  O   . ASP A  1 460 ? 2.046   -15.288 -13.840 1.000 28.432 0 483  ASP A O   1 ? 
ATOM   3708 C  CB  . ASP A  1 460 ? 2.478   -12.452 -15.274 1.000 40.191 0 483  ASP A CB  1 ? 
ATOM   3709 C  CG  . ASP A  1 460 ? 2.490   -11.921 -16.706 1.000 47.292 0 483  ASP A CG  1 ? 
ATOM   3710 O  OD1 . ASP A  1 460 ? 1.633   -12.342 -17.515 1.000 46.558 0 483  ASP A OD1 1 ? 
ATOM   3711 O  OD2 . ASP A  1 460 ? 3.351   -11.076 -17.004 1.000 52.804 0 483  ASP A OD2 1 ? 
ATOM   3712 N  N   . ASP A  1 461 ? 1.160   -13.713 -12.502 1.000 27.483 0 484  ASP A N   1 ? 
ATOM   3713 C  CA  . ASP A  1 461 ? 1.420   -14.484 -11.292 1.000 27.398 0 484  ASP A CA  1 ? 
ATOM   3714 C  C   . ASP A  1 461 ? 0.131   -15.068 -10.698 1.000 24.280 0 484  ASP A C   1 ? 
ATOM   3715 O  O   . ASP A  1 461 ? 0.127   -15.494 -9.546  1.000 24.544 0 484  ASP A O   1 ? 
ATOM   3716 C  CB  . ASP A  1 461 ? 2.141   -13.615 -10.252 1.000 28.914 0 484  ASP A CB  1 ? 
ATOM   3717 C  CG  . ASP A  1 461 ? 1.541   -12.236 -10.043 1.000 29.499 0 484  ASP A CG  1 ? 
ATOM   3718 O  OD1 . ASP A  1 461 ? 0.402   -11.940 -10.598 1.000 27.393 0 484  ASP A OD1 1 ? 
ATOM   3719 O  OD2 . ASP A  1 461 ? 2.168   -11.444 -9.292  1.000 30.283 0 484  ASP A OD2 1 ? 
ATOM   3720 N  N   . SER A  1 462 ? -0.954  -15.083 -11.468 1.000 27.716 0 485  SER A N   1 ? 
ATOM   3721 C  CA  . SER A  1 462 ? -2.214  -15.652 -10.996 1.000 22.997 0 485  SER A CA  1 ? 
ATOM   3722 C  C   . SER A  1 462 ? -2.076  -17.135 -10.699 1.000 24.466 0 485  SER A C   1 ? 
ATOM   3723 O  O   . SER A  1 462 ? -1.268  -17.883 -11.283 1.000 24.163 0 485  SER A O   1 ? 
ATOM   3724 C  CB  . SER A  1 462 ? -3.320  -15.403 -11.999 1.000 22.823 0 485  SER A CB  1 ? 
ATOM   3725 O  OG  . SER A  1 462 ? -3.574  -14.014 -12.096 1.000 26.867 0 485  SER A OG  1 ? 
ATOM   3726 N  N   . GLY A  1 463 ? -2.907  -17.589 -9.758  1.000 22.779 0 486  GLY A N   1 ? 
ATOM   3727 C  CA  . GLY A  1 463 ? -2.818  -18.952 -9.308  1.000 24.452 0 486  GLY A CA  1 ? 
ATOM   3728 C  C   . GLY A  1 463 ? -3.270  -19.070 -7.864  1.000 22.322 0 486  GLY A C   1 ? 
ATOM   3729 O  O   . GLY A  1 463 ? -3.967  -18.196 -7.365  1.000 22.131 0 486  GLY A O   1 ? 
ATOM   3730 N  N   . LEU A  1 464 ? -2.868  -20.178 -7.244  1.000 21.223 0 487  LEU A N   1 ? 
ATOM   3731 C  CA  . LEU A  1 464 ? -3.360  -20.542 -5.926  1.000 22.964 0 487  LEU A CA  1 ? 
ATOM   3732 C  C   . LEU A  1 464 ? -2.228  -21.190 -5.156  1.000 21.130 0 487  LEU A C   1 ? 
ATOM   3733 O  O   . LEU A  1 464 ? -1.727  -22.220 -5.582  1.000 21.888 0 487  LEU A O   1 ? 
ATOM   3734 C  CB  . LEU A  1 464 ? -4.513  -21.523 -6.103  1.000 23.601 0 487  LEU A CB  1 ? 
ATOM   3735 C  CG  . LEU A  1 464 ? -5.438  -21.700 -4.911  1.000 24.462 0 487  LEU A CG  1 ? 
ATOM   3736 C  CD1 . LEU A  1 464 ? -6.253  -20.439 -4.671  1.000 24.480 0 487  LEU A CD1 1 ? 
ATOM   3737 C  CD2 . LEU A  1 464 ? -6.333  -22.908 -5.087  1.000 23.960 0 487  LEU A CD2 1 ? 
ATOM   3738 N  N   . GLN A  1 465 ? -1.899  -20.627 -3.989  1.000 20.094 0 488  GLN A N   1 ? 
ATOM   3739 C  CA  . GLN A  1 465 ? -0.932  -21.263 -3.108  1.000 20.077 0 488  GLN A CA  1 ? 
ATOM   3740 C  C   . GLN A  1 465 ? -1.720  -22.166 -2.168  1.000 21.283 0 488  GLN A C   1 ? 
ATOM   3741 O  O   . GLN A  1 465 ? -2.593  -21.696 -1.426  1.000 20.487 0 488  GLN A O   1 ? 
ATOM   3742 C  CB  . GLN A  1 465 ? -0.122  -20.189 -2.376  1.000 19.751 0 488  GLN A CB  1 ? 
ATOM   3743 C  CG  . GLN A  1 465 ? 1.030   -20.751 -1.542  1.000 20.547 0 488  GLN A CG  1 ? 
ATOM   3744 C  CD  . GLN A  1 465 ? 2.273   -21.055 -2.359  1.000 21.106 0 488  GLN A CD  1 ? 
ATOM   3745 O  OE1 . GLN A  1 465 ? 2.586   -20.338 -3.310  1.000 21.896 0 488  GLN A OE1 1 ? 
ATOM   3746 N  NE2 . GLN A  1 465 ? 3.037   -22.059 -1.935  1.000 20.819 0 488  GLN A NE2 1 ? 
ATOM   3747 N  N   . VAL A  1 466 ? -1.367  -23.446 -2.155  1.000 18.705 0 489  VAL A N   1 ? 
ATOM   3748 C  CA  . VAL A  1 466 ? -2.053  -24.472 -1.399  1.000 19.630 0 489  VAL A CA  1 ? 
ATOM   3749 C  C   . VAL A  1 466 ? -1.146  -24.942 -0.269  1.000 22.793 0 489  VAL A C   1 ? 
ATOM   3750 O  O   . VAL A  1 466 ? 0.006   -25.308 -0.562  1.000 22.729 0 489  VAL A O   1 ? 
ATOM   3751 C  CB  . VAL A  1 466 ? -2.428  -25.635 -2.320  1.000 20.188 0 489  VAL A CB  1 ? 
ATOM   3752 C  CG1 . VAL A  1 466 ? -3.183  -26.703 -1.547  1.000 22.773 0 489  VAL A CG1 1 ? 
ATOM   3753 C  CG2 . VAL A  1 466 ? -3.221  -25.152 -3.536  1.000 20.905 0 489  VAL A CG2 1 ? 
ATOM   3754 N  N   . SER A  1 467 ? -1.631  -24.854 0.991   1.000 21.479 0 490  SER A N   1 ? 
ATOM   3755 C  CA  . SER A  1 467 ? -0.816  -25.134 2.178   1.000 20.144 0 490  SER A CA  1 ? 
ATOM   3756 C  C   . SER A  1 467 ? -1.544  -26.049 3.142   1.000 21.533 0 490  SER A C   1 ? 
ATOM   3757 O  O   . SER A  1 467 ? -2.758  -25.909 3.359   1.000 20.091 0 490  SER A O   1 ? 
ATOM   3758 C  CB  . SER A  1 467 ? -0.404  -23.887 2.923   1.000 18.406 0 490  SER A CB  1 ? 
ATOM   3759 O  OG  . SER A  1 467 ? 0.111   -22.899 2.076   1.000 18.732 0 490  SER A OG  1 ? 
ATOM   3760 N  N   . LEU A  1 468 ? -0.805  -26.997 3.726   1.000 19.133 0 491  LEU A N   1 ? 
ATOM   3761 C  CA  . LEU A  1 468 ? -1.292  -27.724 4.888   1.000 19.146 0 491  LEU A CA  1 ? 
ATOM   3762 C  C   . LEU A  1 468 ? -0.688  -27.059 6.119   1.000 19.962 0 491  LEU A C   1 ? 
ATOM   3763 O  O   . LEU A  1 468 ? 0.524   -26.790 6.131   1.000 21.076 0 491  LEU A O   1 ? 
ATOM   3764 C  CB  . LEU A  1 468 ? -0.938  -29.221 4.801   1.000 22.621 0 491  LEU A CB  1 ? 
ATOM   3765 C  CG  . LEU A  1 468 ? -1.567  -30.020 3.658   1.000 23.330 0 491  LEU A CG  1 ? 
ATOM   3766 C  CD1 . LEU A  1 468 ? -0.994  -31.425 3.577   1.000 23.450 0 491  LEU A CD1 1 ? 
ATOM   3767 C  CD2 . LEU A  1 468 ? -3.093  -30.113 3.838   1.000 24.899 0 491  LEU A CD2 1 ? 
ATOM   3768 N  N   . THR A  1 469 ? -1.540  -26.724 7.112   1.000 18.441 0 492  THR A N   1 ? 
ATOM   3769 C  CA  . THR A  1 469 ? -1.071  -25.981 8.269   1.000 19.957 0 492  THR A CA  1 ? 
ATOM   3770 C  C   . THR A  1 469 ? -1.524  -26.661 9.553   1.000 17.911 0 492  THR A C   1 ? 
ATOM   3771 O  O   . THR A  1 469 ? -2.404  -27.531 9.532   1.000 19.378 0 492  THR A O   1 ? 
ATOM   3772 C  CB  . THR A  1 469 ? -1.505  -24.505 8.236   1.000 19.056 0 492  THR A CB  1 ? 
ATOM   3773 O  OG1 . THR A  1 469 ? -2.920  -24.420 8.422   1.000 22.508 0 492  THR A OG1 1 ? 
ATOM   3774 C  CG2 . THR A  1 469 ? -1.146  -23.802 6.949   1.000 19.468 0 492  THR A CG2 1 ? 
ATOM   3775 N  N   . ASP A  1 470 ? -0.993  -26.157 10.693  1.000 18.775 0 493  ASP A N   1 ? 
ATOM   3776 C  CA  . ASP A  1 470 ? -1.308  -26.706 12.009  1.000 18.384 0 493  ASP A CA  1 ? 
ATOM   3777 C  C   . ASP A  1 470 ? -2.060  -25.691 12.879  1.000 19.236 0 493  ASP A C   1 ? 
ATOM   3778 O  O   . ASP A  1 470 ? -2.295  -25.966 14.048  1.000 19.698 0 493  ASP A O   1 ? 
ATOM   3779 C  CB  . ASP A  1 470 ? -0.088  -27.264 12.754  1.000 19.722 0 493  ASP A CB  1 ? 
ATOM   3780 C  CG  . ASP A  1 470 ? 1.096   -26.341 12.849  1.000 20.576 0 493  ASP A CG  1 ? 
ATOM   3781 O  OD1 . ASP A  1 470 ? 0.983   -25.166 12.405  1.000 21.472 0 493  ASP A OD1 1 ? 
ATOM   3782 O  OD2 . ASP A  1 470 ? 2.199   -26.851 13.207  1.000 25.152 0 493  ASP A OD2 1 ? 
ATOM   3783 N  N   . ARG A  1 471 ? -2.473  -24.563 12.274  1.000 19.034 0 494  ARG A N   1 ? 
ATOM   3784 C  CA  . ARG A  1 471 ? -3.511  -23.721 12.872  1.000 17.570 0 494  ARG A CA  1 ? 
ATOM   3785 C  C   . ARG A  1 471 ? -4.193  -22.899 11.768  1.000 18.337 0 494  ARG A C   1 ? 
ATOM   3786 O  O   . ARG A  1 471 ? -3.822  -22.985 10.594  1.000 18.174 0 494  ARG A O   1 ? 
ATOM   3787 C  CB  . ARG A  1 471 ? -2.905  -22.864 14.000  1.000 16.753 0 494  ARG A CB  1 ? 
ATOM   3788 C  CG  . ARG A  1 471 ? -1.887  -21.819 13.587  1.000 16.439 0 494  ARG A CG  1 ? 
ATOM   3789 C  CD  . ARG A  1 471 ? -0.442  -22.362 13.543  1.000 16.486 0 494  ARG A CD  1 ? 
ATOM   3790 N  NE  . ARG A  1 471 ? 0.530   -21.314 13.657  1.000 17.372 0 494  ARG A NE  1 ? 
ATOM   3791 C  CZ  . ARG A  1 471 ? 1.824   -21.443 13.308  1.000 20.164 0 494  ARG A CZ  1 ? 
ATOM   3792 N  NH1 . ARG A  1 471 ? 2.300   -22.610 12.884  1.000 18.973 0 494  ARG A NH1 1 ? 
ATOM   3793 N  NH2 . ARG A  1 471 ? 2.640   -20.411 13.406  1.000 19.766 0 494  ARG A NH2 1 ? 
ATOM   3794 N  N   . LEU A  1 472 ? -5.215  -22.133 12.147  1.000 17.196 0 495  LEU A N   1 ? 
ATOM   3795 C  CA  . LEU A  1 472 ? -6.020  -21.395 11.194  1.000 16.972 0 495  LEU A CA  1 ? 
ATOM   3796 C  C   . LEU A  1 472 ? -5.316  -20.084 10.843  1.000 17.267 0 495  LEU A C   1 ? 
ATOM   3797 O  O   . LEU A  1 472 ? -5.150  -19.200 11.695  1.000 17.161 0 495  LEU A O   1 ? 
ATOM   3798 C  CB  . LEU A  1 472 ? -7.399  -21.188 11.824  1.000 18.260 0 495  LEU A CB  1 ? 
ATOM   3799 C  CG  . LEU A  1 472 ? -8.490  -20.638 10.898  1.000 17.382 0 495  LEU A CG  1 ? 
ATOM   3800 C  CD1 . LEU A  1 472 ? -9.819  -20.631 11.630  1.000 20.124 0 495  LEU A CD1 1 ? 
ATOM   3801 C  CD2 . LEU A  1 472 ? -8.188  -19.265 10.394  1.000 17.382 0 495  LEU A CD2 1 ? 
ATOM   3802 N  N   . PHE A  1 473 ? -4.847  -19.994 9.594   1.000 17.327 0 496  PHE A N   1 ? 
ATOM   3803 C  CA  . PHE A  1 473 ? -4.312  -18.769 9.023   1.000 16.615 0 496  PHE A CA  1 ? 
ATOM   3804 C  C   . PHE A  1 473 ? -5.418  -18.005 8.298   1.000 15.877 0 496  PHE A C   1 ? 
ATOM   3805 O  O   . PHE A  1 473 ? -6.279  -18.605 7.655   1.000 17.557 0 496  PHE A O   1 ? 
ATOM   3806 C  CB  . PHE A  1 473 ? -3.197  -19.089 8.031   1.000 19.229 0 496  PHE A CB  1 ? 
ATOM   3807 C  CG  . PHE A  1 473 ? -1.900  -19.459 8.699   1.000 17.461 0 496  PHE A CG  1 ? 
ATOM   3808 C  CD1 . PHE A  1 473 ? -1.754  -20.687 9.315   1.000 18.496 0 496  PHE A CD1 1 ? 
ATOM   3809 C  CD2 . PHE A  1 473 ? -0.844  -18.556 8.730   1.000 19.148 0 496  PHE A CD2 1 ? 
ATOM   3810 C  CE1 . PHE A  1 473 ? -0.578  -20.998 9.980   1.000 19.866 0 496  PHE A CE1 1 ? 
ATOM   3811 C  CE2 . PHE A  1 473 ? 0.346   -18.896 9.357   1.000 20.530 0 496  PHE A CE2 1 ? 
ATOM   3812 C  CZ  . PHE A  1 473 ? 0.472   -20.106 9.977   1.000 17.967 0 496  PHE A CZ  1 ? 
ATOM   3813 N  N   . ASN A  1 474 ? -5.360  -16.671 8.366   1.000 16.959 0 497  ASN A N   1 ? 
ATOM   3814 C  CA  . ASN A  1 474 ? -6.357  -15.875 7.672   1.000 16.974 0 497  ASN A CA  1 ? 
ATOM   3815 C  C   . ASN A  1 474 ? -6.377  -16.232 6.192   1.000 17.329 0 497  ASN A C   1 ? 
ATOM   3816 O  O   . ASN A  1 474 ? -5.347  -16.432 5.555   1.000 17.443 0 497  ASN A O   1 ? 
ATOM   3817 C  CB  . ASN A  1 474 ? -6.126  -14.385 7.912   1.000 16.814 0 497  ASN A CB  1 ? 
ATOM   3818 C  CG  . ASN A  1 474 ? -6.679  -13.969 9.257   1.000 17.110 0 497  ASN A CG  1 ? 
ATOM   3819 O  OD1 . ASN A  1 474 ? -7.889  -13.861 9.444   1.000 17.703 0 497  ASN A OD1 1 ? 
ATOM   3820 N  ND2 . ASN A  1 474 ? -5.807  -13.692 10.199  1.000 18.114 0 497  ASN A ND2 1 ? 
ATOM   3821 N  N   . ALA A  1 475 ? -7.581  -16.138 5.622   1.000 17.350 0 498  ALA A N   1 ? 
ATOM   3822 C  CA  . ALA A  1 475 ? -7.824  -16.391 4.218   1.000 18.473 0 498  ALA A CA  1 ? 
ATOM   3823 C  C   . ALA A  1 475 ? -6.991  -15.450 3.358   1.000 20.028 0 498  ALA A C   1 ? 
ATOM   3824 O  O   . ALA A  1 475 ? -6.541  -15.866 2.298   1.000 20.404 0 498  ALA A O   1 ? 
ATOM   3825 C  CB  . ALA A  1 475 ? -9.308  -16.250 3.911   1.000 19.666 0 498  ALA A CB  1 ? 
ATOM   3826 N  N   . CYS A  1 476 ? -6.731  -14.225 3.851   1.000 21.313 0 499  CYS A N   1 ? 
ATOM   3827 C  CA  . CYS A  1 476 ? -6.022  -13.219 3.088   1.000 20.904 0 499  CYS A CA  1 ? 
ATOM   3828 C  C   . CYS A  1 476 ? -4.525  -13.144 3.433   1.000 20.094 0 499  CYS A C   1 ? 
ATOM   3829 O  O   . CYS A  1 476 ? -3.876  -12.206 2.997   1.000 21.991 0 499  CYS A O   1 ? 
ATOM   3830 C  CB  . CYS A  1 476 ? -6.647  -11.839 3.288   1.000 23.130 0 499  CYS A CB  1 ? 
ATOM   3831 S  SG  . CYS A  1 476 ? -6.694  -11.299 5.021   1.000 23.412 0 499  CYS A SG  1 ? 
ATOM   3832 N  N   . ASP A  1 477 ? -3.992  -14.124 4.183   1.000 20.711 0 500  ASP A N   1 ? 
ATOM   3833 C  CA  . ASP A  1 477 ? -2.596  -14.086 4.611   1.000 20.762 0 500  ASP A CA  1 ? 
ATOM   3834 C  C   . ASP A  1 477 ? -1.698  -14.806 3.596   1.000 17.832 0 500  ASP A C   1 ? 
ATOM   3835 O  O   . ASP A  1 477 ? -1.622  -16.028 3.584   1.000 20.450 0 500  ASP A O   1 ? 
ATOM   3836 C  CB  . ASP A  1 477 ? -2.458  -14.665 6.023   1.000 21.206 0 500  ASP A CB  1 ? 
ATOM   3837 C  CG  . ASP A  1 477 ? -1.097  -14.482 6.661   1.000 21.731 0 500  ASP A CG  1 ? 
ATOM   3838 O  OD1 . ASP A  1 477 ? -0.129  -14.087 5.914   1.000 22.029 0 500  ASP A OD1 1 ? 
ATOM   3839 O  OD2 . ASP A  1 477 ? -1.013  -14.732 7.910   1.000 21.023 0 500  ASP A OD2 1 ? 
ATOM   3840 N  N   . SER A  1 478 ? -1.007  -14.009 2.786   1.000 20.304 0 501  SER A N   1 ? 
ATOM   3841 C  CA  . SER A  1 478 ? -0.045  -14.503 1.795   1.000 21.220 0 501  SER A CA  1 ? 
ATOM   3842 C  C   . SER A  1 478 ? 1.228   -15.139 2.387   1.000 23.215 0 501  SER A C   1 ? 
ATOM   3843 O  O   . SER A  1 478 ? 1.935   -15.831 1.653   1.000 21.081 0 501  SER A O   1 ? 
ATOM   3844 C  CB  . SER A  1 478 ? 0.330   -13.371 0.835   1.000 24.878 0 501  SER A CB  1 ? 
ATOM   3845 O  OG  . SER A  1 478 ? -0.778  -13.059 -0.039  1.000 28.978 0 501  SER A OG  1 ? 
ATOM   3846 N  N   . THR A  1 479 ? 1.481   -15.017 3.710   1.000 21.702 0 502  THR A N   1 ? 
ATOM   3847 C  CA  . THR A  1 479 ? 2.685   -15.537 4.337   1.000 19.771 0 502  THR A CA  1 ? 
ATOM   3848 C  C   . THR A  1 479 ? 2.457   -16.949 4.864   1.000 20.926 0 502  THR A C   1 ? 
ATOM   3849 O  O   . THR A  1 479 ? 3.382   -17.604 5.361   1.000 21.423 0 502  THR A O   1 ? 
ATOM   3850 C  CB  . THR A  1 479 ? 3.198   -14.632 5.467   1.000 22.755 0 502  THR A CB  1 ? 
ATOM   3851 O  OG1 . THR A  1 479 ? 2.298   -14.723 6.574   1.000 22.001 0 502  THR A OG1 1 ? 
ATOM   3852 C  CG2 . THR A  1 479 ? 3.427   -13.202 5.026   1.000 21.498 0 502  THR A CG2 1 ? 
ATOM   3853 N  N   . THR A  1 480 ? 1.225   -17.462 4.722   1.000 19.427 0 503  THR A N   1 ? 
ATOM   3854 C  CA  . THR A  1 480 ? 0.869   -18.776 5.239   1.000 18.711 0 503  THR A CA  1 ? 
ATOM   3855 C  C   . THR A  1 480 ? 1.872   -19.850 4.787   1.000 17.849 0 503  THR A C   1 ? 
ATOM   3856 O  O   . THR A  1 480 ? 2.311   -20.674 5.576   1.000 19.018 0 503  THR A O   1 ? 
ATOM   3857 C  CB  . THR A  1 480 ? -0.567  -19.168 4.844   1.000 20.002 0 503  THR A CB  1 ? 
ATOM   3858 O  OG1 . THR A  1 480 ? -1.467  -18.200 5.383   1.000 18.413 0 503  THR A OG1 1 ? 
ATOM   3859 C  CG2 . THR A  1 480 ? -0.917  -20.546 5.346   1.000 18.883 0 503  THR A CG2 1 ? 
ATOM   3860 N  N   . LYS A  1 481 ? 2.240   -19.807 3.521   1.000 20.569 0 504  LYS A N   1 ? 
ATOM   3861 C  CA  . LYS A  1 481 ? 3.195   -20.736 2.940   1.000 19.794 0 504  LYS A CA  1 ? 
ATOM   3862 C  C   . LYS A  1 481 ? 4.534   -20.739 3.689   1.000 20.168 0 504  LYS A C   1 ? 
ATOM   3863 O  O   . LYS A  1 481 ? 5.188   -21.765 3.726   1.000 21.006 0 504  LYS A O   1 ? 
ATOM   3864 C  CB  . LYS A  1 481 ? 3.483   -20.348 1.495   1.000 20.206 0 504  LYS A CB  1 ? 
ATOM   3865 C  CG  . LYS A  1 481 ? 4.032   -18.956 1.279   1.000 22.173 0 504  LYS A CG  1 ? 
ATOM   3866 C  CD  . LYS A  1 481 ? 4.306   -18.607 -0.170  1.000 25.301 0 504  LYS A CD  1 ? 
ATOM   3867 C  CE  . LYS A  1 481 ? 5.064   -17.306 -0.274  1.000 29.637 0 504  LYS A CE  1 ? 
ATOM   3868 N  NZ  . LYS A  1 481 ? 5.062   -16.826 -1.668  1.000 33.696 0 504  LYS A NZ  1 ? 
ATOM   3869 N  N   . ASP A  1 482 ? 4.893   -19.643 4.340   1.000 19.565 0 505  ASP A N   1 ? 
ATOM   3870 C  CA  . ASP A  1 482 ? 6.167   -19.576 5.065   1.000 20.479 0 505  ASP A CA  1 ? 
ATOM   3871 C  C   . ASP A  1 482 ? 6.137   -20.348 6.394   1.000 20.740 0 505  ASP A C   1 ? 
ATOM   3872 O  O   . ASP A  1 482 ? 7.195   -20.709 6.915   1.000 23.965 0 505  ASP A O   1 ? 
ATOM   3873 C  CB  . ASP A  1 482 ? 6.565   -18.124 5.287   1.000 20.210 0 505  ASP A CB  1 ? 
ATOM   3874 C  CG  . ASP A  1 482 ? 6.771   -17.324 4.019   1.000 26.760 0 505  ASP A CG  1 ? 
ATOM   3875 O  OD1 . ASP A  1 482 ? 7.095   -17.938 3.009   1.000 28.568 0 505  ASP A OD1 1 ? 
ATOM   3876 O  OD2 . ASP A  1 482 ? 6.585   -16.092 4.063   1.000 27.601 0 505  ASP A OD2 1 ? 
ATOM   3877 N  N   . TYR A  1 483 ? 4.940   -20.638 6.936   1.000 19.050 0 506  TYR A N   1 ? 
ATOM   3878 C  CA  . TYR A  1 483 ? 4.745   -21.390 8.163   1.000 18.934 0 506  TYR A CA  1 ? 
ATOM   3879 C  C   . TYR A  1 483 ? 4.183   -22.782 7.921   1.000 18.087 0 506  TYR A C   1 ? 
ATOM   3880 O  O   . TYR A  1 483 ? 4.060   -23.562 8.850   1.000 19.963 0 506  TYR A O   1 ? 
ATOM   3881 C  CB  . TYR A  1 483 ? 3.739   -20.632 9.037   1.000 18.865 0 506  TYR A CB  1 ? 
ATOM   3882 C  CG  . TYR A  1 483 ? 4.146   -19.222 9.431   1.000 18.399 0 506  TYR A CG  1 ? 
ATOM   3883 C  CD1 . TYR A  1 483 ? 3.881   -18.126 8.616   1.000 17.660 0 506  TYR A CD1 1 ? 
ATOM   3884 C  CD2 . TYR A  1 483 ? 4.851   -19.001 10.604  1.000 18.301 0 506  TYR A CD2 1 ? 
ATOM   3885 C  CE1 . TYR A  1 483 ? 4.293   -16.850 8.976   1.000 18.799 0 506  TYR A CE1 1 ? 
ATOM   3886 C  CE2 . TYR A  1 483 ? 5.241   -17.726 10.999  1.000 17.516 0 506  TYR A CE2 1 ? 
ATOM   3887 C  CZ  . TYR A  1 483 ? 4.955   -16.651 10.173  1.000 18.827 0 506  TYR A CZ  1 ? 
ATOM   3888 O  OH  . TYR A  1 483 ? 5.301   -15.436 10.601  1.000 19.493 0 506  TYR A OH  1 ? 
ATOM   3889 N  N   . ALA A  1 484 ? 3.863   -23.109 6.664   1.000 20.308 0 507  ALA A N   1 ? 
ATOM   3890 C  CA  . ALA A  1 484 ? 3.128   -24.310 6.319   1.000 19.244 0 507  ALA A CA  1 ? 
ATOM   3891 C  C   . ALA A  1 484 ? 3.953   -25.586 6.527   1.000 21.246 0 507  ALA A C   1 ? 
ATOM   3892 O  O   . ALA A  1 484 ? 5.164   -25.593 6.353   1.000 23.012 0 507  ALA A O   1 ? 
ATOM   3893 C  CB  . ALA A  1 484 ? 2.657   -24.181 4.881   1.000 20.891 0 507  ALA A CB  1 ? 
ATOM   3894 N  N   . LEU A  1 485 ? 3.282   -26.673 6.849   1.000 21.128 0 508  LEU A N   1 ? 
ATOM   3895 C  CA  . LEU A  1 485 ? 3.930   -27.980 6.940   1.000 22.058 0 508  LEU A CA  1 ? 
ATOM   3896 C  C   . LEU A  1 485 ? 4.284   -28.414 5.525   1.000 23.178 0 508  LEU A C   1 ? 
ATOM   3897 O  O   . LEU A  1 485 ? 5.437   -28.794 5.239   1.000 23.044 0 508  LEU A O   1 ? 
ATOM   3898 C  CB  . LEU A  1 485 ? 3.014   -29.038 7.547   1.000 23.664 0 508  LEU A CB  1 ? 
ATOM   3899 C  CG  . LEU A  1 485 ? 2.805   -28.993 9.041   1.000 29.509 0 508  LEU A CG  1 ? 
ATOM   3900 C  CD1 . LEU A  1 485 ? 2.033   -27.779 9.408   1.000 33.348 0 508  LEU A CD1 1 ? 
ATOM   3901 C  CD2 . LEU A  1 485 ? 2.074   -30.226 9.509   1.000 30.973 0 508  LEU A CD2 1 ? 
ATOM   3902 N  N   . PHE A  1 486 ? 3.312   -28.264 4.617   1.000 21.669 0 509  PHE A N   1 ? 
ATOM   3903 C  CA  . PHE A  1 486 ? 3.554   -28.495 3.191   1.000 21.192 0 509  PHE A CA  1 ? 
ATOM   3904 C  C   . PHE A  1 486 ? 2.883   -27.382 2.391   1.000 23.289 0 509  PHE A C   1 ? 
ATOM   3905 O  O   . PHE A  1 486 ? 1.823   -26.889 2.780   1.000 23.727 0 509  PHE A O   1 ? 
ATOM   3906 C  CB  . PHE A  1 486 ? 3.041   -29.869 2.759   1.000 21.450 0 509  PHE A CB  1 ? 
ATOM   3907 C  CG  . PHE A  1 486 ? 3.629   -31.028 3.501   1.000 20.825 0 509  PHE A CG  1 ? 
ATOM   3908 C  CD1 . PHE A  1 486 ? 4.848   -31.567 3.105   1.000 23.487 0 509  PHE A CD1 1 ? 
ATOM   3909 C  CD2 . PHE A  1 486 ? 2.988   -31.576 4.589   1.000 24.460 0 509  PHE A CD2 1 ? 
ATOM   3910 C  CE1 . PHE A  1 486 ? 5.395   -32.636 3.795   1.000 21.002 0 509  PHE A CE1 1 ? 
ATOM   3911 C  CE2 . PHE A  1 486 ? 3.561   -32.616 5.305   1.000 24.388 0 509  PHE A CE2 1 ? 
ATOM   3912 C  CZ  . PHE A  1 486 ? 4.777   -33.130 4.903   1.000 23.215 0 509  PHE A CZ  1 ? 
ATOM   3913 N  N   . THR A  1 487 ? 3.503   -26.968 1.289   1.000 23.125 0 510  THR A N   1 ? 
ATOM   3914 C  CA  . THR A  1 487 ? 2.955   -25.909 0.467   1.000 21.820 0 510  THR A CA  1 ? 
ATOM   3915 C  C   . THR A  1 487 ? 3.448   -26.038 -0.974  1.000 28.373 0 510  THR A C   1 ? 
ATOM   3916 O  O   . THR A  1 487 ? 4.564   -26.506 -1.229  1.000 23.211 0 510  THR A O   1 ? 
ATOM   3917 C  CB  . THR A  1 487 ? 3.302   -24.539 1.066   1.000 21.754 0 510  THR A CB  1 ? 
ATOM   3918 O  OG1 . THR A  1 487 ? 2.469   -23.549 0.464   1.000 21.406 0 510  THR A OG1 1 ? 
ATOM   3919 C  CG2 . THR A  1 487 ? 4.749   -24.145 0.855   1.000 23.119 0 510  THR A CG2 1 ? 
ATOM   3920 N  N   . PHE A  1 488 ? 2.599   -25.609 -1.925  1.000 24.643 0 511  PHE A N   1 ? 
ATOM   3921 C  CA  . PHE A  1 488 ? 2.981   -25.554 -3.333  1.000 25.345 0 511  PHE A CA  1 ? 
ATOM   3922 C  C   . PHE A  1 488 ? 2.033   -24.624 -4.083  1.000 24.877 0 511  PHE A C   1 ? 
ATOM   3923 O  O   . PHE A  1 488 ? 0.883   -24.444 -3.667  1.000 21.245 0 511  PHE A O   1 ? 
ATOM   3924 C  CB  . PHE A  1 488 ? 2.976   -26.954 -3.965  1.000 24.246 0 511  PHE A CB  1 ? 
ATOM   3925 C  CG  . PHE A  1 488 ? 1.597   -27.510 -4.211  1.000 23.295 0 511  PHE A CG  1 ? 
ATOM   3926 C  CD1 . PHE A  1 488 ? 0.883   -28.124 -3.194  1.000 24.018 0 511  PHE A CD1 1 ? 
ATOM   3927 C  CD2 . PHE A  1 488 ? 0.994   -27.340 -5.448  1.000 28.442 0 511  PHE A CD2 1 ? 
ATOM   3928 C  CE1 . PHE A  1 488 ? -0.419  -28.548 -3.396  1.000 24.519 0 511  PHE A CE1 1 ? 
ATOM   3929 C  CE2 . PHE A  1 488 ? -0.297  -27.801 -5.667  1.000 27.282 0 511  PHE A CE2 1 ? 
ATOM   3930 C  CZ  . PHE A  1 488 ? -0.986  -28.412 -4.644  1.000 24.465 0 511  PHE A CZ  1 ? 
ATOM   3931 N  N   . PRO A  1 489 ? 2.475   -24.004 -5.201  1.000 25.290 0 512  PRO A N   1 ? 
ATOM   3932 C  CA  . PRO A  1 489 ? 1.599   -23.177 -6.031  1.000 24.465 0 512  PRO A CA  1 ? 
ATOM   3933 C  C   . PRO A  1 489 ? 1.003   -23.926 -7.223  1.000 28.091 0 512  PRO A C   1 ? 
ATOM   3934 O  O   . PRO A  1 489 ? 1.664   -24.760 -7.843  1.000 25.504 0 512  PRO A O   1 ? 
ATOM   3935 C  CB  . PRO A  1 489 ? 2.514   -22.055 -6.493  1.000 24.317 0 512  PRO A CB  1 ? 
ATOM   3936 C  CG  . PRO A  1 489 ? 3.915   -22.692 -6.518  1.000 24.709 0 512  PRO A CG  1 ? 
ATOM   3937 C  CD  . PRO A  1 489 ? 3.878   -23.926 -5.644  1.000 26.504 0 512  PRO A CD  1 ? 
ATOM   3938 N  N   . ILE A  1 490 ? -0.287  -23.659 -7.473  1.000 25.267 0 513  ILE A N   1 ? 
ATOM   3939 C  CA  . ILE A  1 490 ? -0.903  -23.848 -8.779  1.000 23.661 0 513  ILE A CA  1 ? 
ATOM   3940 C  C   . ILE A  1 490 ? -0.702  -22.553 -9.552  1.000 24.234 0 513  ILE A C   1 ? 
ATOM   3941 O  O   . ILE A  1 490 ? -1.073  -21.480 -9.065  1.000 25.176 0 513  ILE A O   1 ? 
ATOM   3942 C  CB  . ILE A  1 490 ? -2.396  -24.162 -8.610  1.000 23.575 0 513  ILE A CB  1 ? 
ATOM   3943 C  CG1 . ILE A  1 490 ? -2.629  -25.453 -7.838  1.000 24.266 0 513  ILE A CG1 1 ? 
ATOM   3944 C  CG2 . ILE A  1 490 ? -3.067  -24.157 -9.979  1.000 28.013 0 513  ILE A CG2 1 ? 
ATOM   3945 C  CD1 . ILE A  1 490 ? -4.103  -25.721 -7.480  1.000 24.923 0 513  ILE A CD1 1 ? 
ATOM   3946 N  N   . ARG A  1 491 ? -0.003  -22.615 -10.694 1.000 24.355 0 514  ARG A N   1 ? 
ATOM   3947 C  CA  . ARG A  1 491 ? 0.273   -21.429 -11.491 1.000 25.911 0 514  ARG A CA  1 ? 
ATOM   3948 C  C   . ARG A  1 491 ? -0.546  -21.479 -12.779 1.000 28.659 0 514  ARG A C   1 ? 
ATOM   3949 O  O   . ARG A  1 491 ? -0.689  -22.544 -13.366 1.000 27.613 0 514  ARG A O   1 ? 
ATOM   3950 C  CB  . ARG A  1 491 ? 1.769   -21.367 -11.826 1.000 32.790 0 514  ARG A CB  1 ? 
ATOM   3951 C  CG  . ARG A  1 491 ? 2.599   -20.877 -10.653 1.000 36.903 0 514  ARG A CG  1 ? 
ATOM   3952 C  CD  . ARG A  1 491 ? 4.068   -21.103 -10.855 1.000 46.186 0 514  ARG A CD  1 ? 
ATOM   3953 N  NE  . ARG A  1 491 ? 4.746   -20.464 -9.736  1.000 49.963 0 514  ARG A NE  1 ? 
ATOM   3954 C  CZ  . ARG A  1 491 ? 6.057   -20.304 -9.641  1.000 52.783 0 514  ARG A CZ  1 ? 
ATOM   3955 N  NH1 . ARG A  1 491 ? 6.858   -20.826 -10.558 1.000 49.057 0 514  ARG A NH1 1 ? 
ATOM   3956 N  NH2 . ARG A  1 491 ? 6.557   -19.636 -8.613  1.000 50.995 0 514  ARG A NH2 1 ? 
ATOM   3957 N  N   . LEU A  1 492 ? -1.065  -20.330 -13.198 1.000 25.959 0 515  LEU A N   1 ? 
ATOM   3958 C  CA  . LEU A  1 492 ? -1.950  -20.267 -14.347 1.000 28.638 0 515  LEU A CA  1 ? 
ATOM   3959 C  C   . LEU A  1 492 ? -1.209  -19.828 -15.597 1.000 30.411 0 515  LEU A C   1 ? 
ATOM   3960 O  O   . LEU A  1 492 ? -1.685  -20.106 -16.683 1.000 32.564 0 515  LEU A O   1 ? 
ATOM   3961 C  CB  . LEU A  1 492 ? -3.085  -19.286 -14.055 1.000 30.021 0 515  LEU A CB  1 ? 
ATOM   3962 C  CG  . LEU A  1 492 ? -3.925  -19.670 -12.842 1.000 29.270 0 515  LEU A CG  1 ? 
ATOM   3963 C  CD1 . LEU A  1 492 ? -5.194  -18.843 -12.798 1.000 33.404 0 515  LEU A CD1 1 ? 
ATOM   3964 C  CD2 . LEU A  1 492 ? -4.242  -21.154 -12.888 1.000 29.184 0 515  LEU A CD2 1 ? 
ATOM   3965 N  N   . LYS A  1 493 ? -0.080  -19.136 -15.446 1.000 36.811 0 516  LYS A N   1 ? 
ATOM   3966 C  CA  . LYS A  1 493 ? 0.677   -18.645 -16.601 1.000 38.204 0 516  LYS A CA  1 ? 
ATOM   3967 C  C   . LYS A  1 493 ? 2.106   -19.167 -16.553 1.000 41.421 0 516  LYS A C   1 ? 
ATOM   3968 O  O   . LYS A  1 493 ? 2.620   -19.446 -15.468 1.000 35.800 0 516  LYS A O   1 ? 
ATOM   3969 C  CB  . LYS A  1 493 ? 0.719   -17.118 -16.625 1.000 40.182 0 516  LYS A CB  1 ? 
ATOM   3970 C  CG  . LYS A  1 493 ? -0.606  -16.449 -16.939 1.000 45.122 0 516  LYS A CG  1 ? 
ATOM   3971 C  CD  . LYS A  1 493 ? -0.973  -16.637 -18.387 1.000 51.749 0 516  LYS A CD  1 ? 
ATOM   3972 C  CE  . LYS A  1 493 ? -2.203  -15.869 -18.798 1.000 54.115 0 516  LYS A CE  1 ? 
ATOM   3973 N  NZ  . LYS A  1 493 ? -2.001  -14.405 -18.690 1.000 59.527 0 516  LYS A NZ  1 ? 
ATOM   3974 N  N   . PRO A  1 494 ? 2.811   -19.340 -17.704 1.000 44.082 0 517  PRO A N   1 ? 
ATOM   3975 C  CA  . PRO A  1 494 ? 2.281   -19.084 -19.049 1.000 41.231 0 517  PRO A CA  1 ? 
ATOM   3976 C  C   . PRO A  1 494 ? 1.109   -19.967 -19.482 1.000 36.132 0 517  PRO A C   1 ? 
ATOM   3977 O  O   . PRO A  1 494 ? 0.247   -19.508 -20.218 1.000 36.241 0 517  PRO A O   1 ? 
ATOM   3978 C  CB  . PRO A  1 494 ? 3.456   -19.395 -19.999 1.000 41.950 0 517  PRO A CB  1 ? 
ATOM   3979 C  CG  . PRO A  1 494 ? 4.684   -19.350 -19.120 1.000 46.053 0 517  PRO A CG  1 ? 
ATOM   3980 C  CD  . PRO A  1 494 ? 4.219   -19.761 -17.734 1.000 44.898 0 517  PRO A CD  1 ? 
ATOM   3981 N  N   . ALA A  1 495 ? 1.132   -21.232 -19.049 1.000 40.786 0 518  ALA A N   1 ? 
ATOM   3982 C  CA  . ALA A  1 495 ? -0.012  -22.127 -19.107 1.000 42.316 0 518  ALA A CA  1 ? 
ATOM   3983 C  C   . ALA A  1 495 ? -0.201  -22.749 -17.724 1.000 35.371 0 518  ALA A C   1 ? 
ATOM   3984 O  O   . ALA A  1 495 ? 0.726   -22.753 -16.922 1.000 34.405 0 518  ALA A O   1 ? 
ATOM   3985 C  CB  . ALA A  1 495 ? 0.191   -23.194 -20.165 1.000 41.675 0 518  ALA A CB  1 ? 
ATOM   3986 N  N   . PRO A  1 496 ? -1.391  -23.281 -17.395 1.000 34.132 0 519  PRO A N   1 ? 
ATOM   3987 C  CA  . PRO A  1 496 ? -1.626  -23.855 -16.070 1.000 30.160 0 519  PRO A CA  1 ? 
ATOM   3988 C  C   . PRO A  1 496 ? -0.785  -25.075 -15.762 1.000 32.192 0 519  PRO A C   1 ? 
ATOM   3989 O  O   . PRO A  1 496 ? -0.697  -25.991 -16.578 1.000 30.556 0 519  PRO A O   1 ? 
ATOM   3990 C  CB  . PRO A  1 496 ? -3.115  -24.253 -16.099 1.000 32.431 0 519  PRO A CB  1 ? 
ATOM   3991 C  CG  . PRO A  1 496 ? -3.711  -23.357 -17.168 1.000 35.613 0 519  PRO A CG  1 ? 
ATOM   3992 C  CD  . PRO A  1 496 ? -2.620  -23.215 -18.211 1.000 34.330 0 519  PRO A CD  1 ? 
ATOM   3993 N  N   . HIS A  1 497 ? -0.202  -25.086 -14.556 1.000 28.638 0 520  HIS A N   1 ? 
ATOM   3994 C  CA  . HIS A  1 497 ? 0.631   -26.176 -14.105 1.000 29.264 0 520  HIS A CA  1 ? 
ATOM   3995 C  C   . HIS A  1 497 ? 0.781   -26.128 -12.589 1.000 27.819 0 520  HIS A C   1 ? 
ATOM   3996 O  O   . HIS A  1 497 ? 0.641   -25.061 -12.007 1.000 26.334 0 520  HIS A O   1 ? 
ATOM   3997 C  CB  . HIS A  1 497 ? 1.995   -26.117 -14.802 1.000 29.106 0 520  HIS A CB  1 ? 
ATOM   3998 C  CG  . HIS A  1 497 ? 2.790   -24.906 -14.490 1.000 29.044 0 520  HIS A CG  1 ? 
ATOM   3999 N  ND1 . HIS A  1 497 ? 2.547   -23.692 -15.088 1.000 29.362 0 520  HIS A ND1 1 ? 
ATOM   4000 C  CD2 . HIS A  1 497 ? 3.815   -24.722 -13.643 1.000 30.612 0 520  HIS A CD2 1 ? 
ATOM   4001 C  CE1 . HIS A  1 497 ? 3.389   -22.796 -14.593 1.000 31.893 0 520  HIS A CE1 1 ? 
ATOM   4002 N  NE2 . HIS A  1 497 ? 4.175   -23.404 -13.710 1.000 28.802 0 520  HIS A NE2 1 ? 
ATOM   4003 N  N   . LEU A  1 498 ? 1.023   -27.294 -11.980 1.000 25.985 0 521  LEU A N   1 ? 
ATOM   4004 C  CA  . LEU A  1 498 ? 1.498   -27.387 -10.602 1.000 26.360 0 521  LEU A CA  1 ? 
ATOM   4005 C  C   . LEU A  1 498 ? 3.023   -27.230 -10.601 1.000 33.825 0 521  LEU A C   1 ? 
ATOM   4006 O  O   . LEU A  1 498 ? 3.699   -27.783 -11.471 1.000 31.530 0 521  LEU A O   1 ? 
ATOM   4007 C  CB  . LEU A  1 498 ? 1.176   -28.750 -9.997  1.000 28.374 0 521  LEU A CB  1 ? 
ATOM   4008 C  CG  . LEU A  1 498 ? -0.196  -29.350 -10.277 1.000 30.237 0 521  LEU A CG  1 ? 
ATOM   4009 C  CD1 . LEU A  1 498 ? -0.370  -30.639 -9.504  1.000 33.433 0 521  LEU A CD1 1 ? 
ATOM   4010 C  CD2 . LEU A  1 498 ? -1.298  -28.367 -9.912  1.000 31.444 0 521  LEU A CD2 1 ? 
ATOM   4011 N  N   . LEU A  1 499 ? 3.583   -26.495 -9.632  1.000 29.707 0 522  LEU A N   1 ? 
ATOM   4012 C  CA  . LEU A  1 499 ? 5.028   -26.513 -9.421  1.000 30.928 0 522  LEU A CA  1 ? 
ATOM   4013 C  C   . LEU A  1 499 ? 5.329   -27.304 -8.158  1.000 33.138 0 522  LEU A C   1 ? 
ATOM   4014 O  O   . LEU A  1 499 ? 4.939   -26.869 -7.077  1.000 29.881 0 522  LEU A O   1 ? 
ATOM   4015 C  CB  . LEU A  1 499 ? 5.525   -25.079 -9.296  1.000 35.910 0 522  LEU A CB  1 ? 
ATOM   4016 C  CG  . LEU A  1 499 ? 7.020   -24.942 -9.006  1.000 44.911 0 522  LEU A CG  1 ? 
ATOM   4017 C  CD1 . LEU A  1 499 ? 7.857   -25.611 -10.109 1.000 47.087 0 522  LEU A CD1 1 ? 
ATOM   4018 C  CD2 . LEU A  1 499 ? 7.395   -23.477 -8.870  1.000 46.808 0 522  LEU A CD2 1 ? 
ATOM   4019 N  N   . LEU A  1 500 ? 5.940   -28.492 -8.300  1.000 30.359 0 523  LEU A N   1 ? 
ATOM   4020 C  CA  . LEU A  1 500 ? 6.227   -29.388 -7.193  1.000 32.745 0 523  LEU A CA  1 ? 
ATOM   4021 C  C   . LEU A  1 500 ? 7.739   -29.454 -7.011  1.000 46.799 0 523  LEU A C   1 ? 
ATOM   4022 O  O   . LEU A  1 500 ? 8.403   -30.381 -7.488  1.000 49.460 0 523  LEU A O   1 ? 
ATOM   4023 C  CB  . LEU A  1 500 ? 5.620   -30.766 -7.454  1.000 31.921 0 523  LEU A CB  1 ? 
ATOM   4024 C  CG  . LEU A  1 500 ? 4.110   -30.777 -7.680  1.000 33.407 0 523  LEU A CG  1 ? 
ATOM   4025 C  CD1 . LEU A  1 500 ? 3.615   -32.176 -7.957  1.000 36.933 0 523  LEU A CD1 1 ? 
ATOM   4026 C  CD2 . LEU A  1 500 ? 3.392   -30.221 -6.457  1.000 35.524 0 523  LEU A CD2 1 ? 
ATOM   4027 N  N   . GLY A  1 501 ? 8.229   -28.438 -6.295  1.000 51.290 0 524  GLY A N   1 ? 
ATOM   4028 C  CA  . GLY A  1 501 ? 9.633   -28.098 -6.219  1.000 49.682 0 524  GLY A CA  1 ? 
ATOM   4029 C  C   . GLY A  1 501 ? 10.121  -27.533 -7.540  1.000 46.744 0 524  GLY A C   1 ? 
ATOM   4030 O  O   . GLY A  1 501 ? 9.891   -26.373 -7.851  1.000 48.077 0 524  GLY A O   1 ? 
ATOM   4031 N  N   . MET A  1 502 ? 10.794  -28.405 -8.300  1.000 51.325 0 525  MET A N   1 ? 
ATOM   4032 C  CA  . MET A  1 502 ? 11.404  -28.080 -9.580  1.000 54.093 0 525  MET A CA  1 ? 
ATOM   4033 C  C   . MET A  1 502 ? 10.448  -28.419 -10.734 1.000 48.832 0 525  MET A C   1 ? 
ATOM   4034 O  O   . MET A  1 502 ? 10.371  -27.701 -11.727 1.000 57.595 0 525  MET A O   1 ? 
ATOM   4035 C  CB  . MET A  1 502 ? 12.682  -28.916 -9.712  1.000 59.042 0 525  MET A CB  1 ? 
ATOM   4036 C  CG  . MET A  1 502 ? 13.671  -28.711 -8.566  1.000 65.199 0 525  MET A CG  1 ? 
ATOM   4037 S  SD  . MET A  1 502 ? 14.183  -26.968 -8.355  1.000 80.083 0 525  MET A SD  1 ? 
ATOM   4038 C  CE  . MET A  1 502 ? 15.965  -27.093 -8.525  1.000 65.204 0 525  MET A CE  1 ? 
ATOM   4039 N  N   . LYS A  1 503 ? 9.668   -29.490 -10.544 1.000 47.196 0 526  LYS A N   1 ? 
ATOM   4040 C  CA  . LYS A  1 503 ? 8.881   -30.125 -11.592 1.000 42.726 0 526  LYS A CA  1 ? 
ATOM   4041 C  C   . LYS A  1 503 ? 7.593   -29.358 -11.879 1.000 45.760 0 526  LYS A C   1 ? 
ATOM   4042 O  O   . LYS A  1 503 ? 6.784   -29.171 -10.971 1.000 42.471 0 526  LYS A O   1 ? 
ATOM   4043 C  CB  . LYS A  1 503 ? 8.550   -31.543 -11.127 1.000 39.337 0 526  LYS A CB  1 ? 
ATOM   4044 C  CG  . LYS A  1 503 ? 7.813   -32.407 -12.123 1.000 37.561 0 526  LYS A CG  1 ? 
ATOM   4045 C  CD  . LYS A  1 503 ? 7.594   -33.767 -11.568 1.000 41.463 0 526  LYS A CD  1 ? 
ATOM   4046 C  CE  . LYS A  1 503 ? 6.937   -34.699 -12.562 1.000 44.659 0 526  LYS A CE  1 ? 
ATOM   4047 N  NZ  . LYS A  1 503 ? 6.720   -36.021 -11.932 1.000 47.126 0 526  LYS A NZ  1 ? 
ATOM   4048 N  N   . LYS A  1 504 ? 7.413   -28.923 -13.134 1.000 43.103 0 527  LYS A N   1 ? 
ATOM   4049 C  CA  . LYS A  1 504 ? 6.148   -28.390 -13.610 1.000 41.614 0 527  LYS A CA  1 ? 
ATOM   4050 C  C   . LYS A  1 504 ? 5.224   -29.525 -14.058 1.000 41.114 0 527  LYS A C   1 ? 
ATOM   4051 O  O   . LYS A  1 504 ? 5.634   -30.392 -14.820 1.000 35.353 0 527  LYS A O   1 ? 
ATOM   4052 C  CB  . LYS A  1 504 ? 6.388   -27.442 -14.775 1.000 42.488 0 527  LYS A CB  1 ? 
ATOM   4053 C  CG  . LYS A  1 504 ? 7.209   -26.205 -14.445 1.000 50.195 0 527  LYS A CG  1 ? 
ATOM   4054 C  CD  . LYS A  1 504 ? 7.297   -25.231 -15.625 1.000 58.014 0 527  LYS A CD  1 ? 
ATOM   4055 C  CE  . LYS A  1 504 ? 6.012   -25.156 -16.438 1.000 62.468 0 527  LYS A CE  1 ? 
ATOM   4056 N  NZ  . LYS A  1 504 ? 5.868   -23.885 -17.200 1.000 59.485 0 527  LYS A NZ  1 ? 
ATOM   4057 N  N   . VAL A  1 505 ? 3.976   -29.560 -13.562 1.000 34.692 0 528  VAL A N   1 ? 
ATOM   4058 C  CA  . VAL A  1 505 ? 3.032   -30.609 -13.927 1.000 31.659 0 528  VAL A CA  1 ? 
ATOM   4059 C  C   . VAL A  1 505 ? 1.843   -29.944 -14.602 1.000 34.626 0 528  VAL A C   1 ? 
ATOM   4060 O  O   . VAL A  1 505 ? 1.037   -29.308 -13.929 1.000 32.508 0 528  VAL A O   1 ? 
ATOM   4061 C  CB  . VAL A  1 505 ? 2.572   -31.420 -12.712 1.000 33.973 0 528  VAL A CB  1 ? 
ATOM   4062 C  CG1 . VAL A  1 505 ? 1.645   -32.561 -13.091 1.000 31.684 0 528  VAL A CG1 1 ? 
ATOM   4063 C  CG2 . VAL A  1 505 ? 3.759   -31.944 -11.922 1.000 37.198 0 528  VAL A CG2 1 ? 
ATOM   4064 N  N   . PRO A  1 506 ? 1.708   -30.016 -15.944 1.000 36.800 0 529  PRO A N   1 ? 
ATOM   4065 C  CA  . PRO A  1 506 ? 0.693   -29.224 -16.640 1.000 34.045 0 529  PRO A CA  1 ? 
ATOM   4066 C  C   . PRO A  1 506 ? -0.684  -29.840 -16.383 1.000 27.893 0 529  PRO A C   1 ? 
ATOM   4067 O  O   . PRO A  1 506 ? -0.797  -31.023 -16.091 1.000 31.125 0 529  PRO A O   1 ? 
ATOM   4068 C  CB  . PRO A  1 506 ? 1.121   -29.285 -18.123 1.000 37.826 0 529  PRO A CB  1 ? 
ATOM   4069 C  CG  . PRO A  1 506 ? 1.906   -30.577 -18.229 1.000 40.378 0 529  PRO A CG  1 ? 
ATOM   4070 C  CD  . PRO A  1 506 ? 2.513   -30.843 -16.861 1.000 39.839 0 529  PRO A CD  1 ? 
ATOM   4071 N  N   . PHE A  1 507 ? -1.721  -29.033 -16.552 1.000 29.790 0 530  PHE A N   1 ? 
ATOM   4072 C  CA  . PHE A  1 507 ? -3.089  -29.529 -16.534 1.000 30.852 0 530  PHE A CA  1 ? 
ATOM   4073 C  C   . PHE A  1 507 ? -3.955  -28.623 -17.416 1.000 29.826 0 530  PHE A C   1 ? 
ATOM   4074 O  O   . PHE A  1 507 ? -3.579  -27.507 -17.760 1.000 30.629 0 530  PHE A O   1 ? 
ATOM   4075 C  CB  . PHE A  1 507 ? -3.608  -29.627 -15.091 1.000 31.743 0 530  PHE A CB  1 ? 
ATOM   4076 C  CG  . PHE A  1 507 ? -3.732  -28.296 -14.395 1.000 28.199 0 530  PHE A CG  1 ? 
ATOM   4077 C  CD1 . PHE A  1 507 ? -4.878  -27.526 -14.535 1.000 28.015 0 530  PHE A CD1 1 ? 
ATOM   4078 C  CD2 . PHE A  1 507 ? -2.695  -27.817 -13.605 1.000 28.410 0 530  PHE A CD2 1 ? 
ATOM   4079 C  CE1 . PHE A  1 507 ? -4.975  -26.290 -13.910 1.000 28.800 0 530  PHE A CE1 1 ? 
ATOM   4080 C  CE2 . PHE A  1 507 ? -2.801  -26.590 -12.973 1.000 25.996 0 530  PHE A CE2 1 ? 
ATOM   4081 C  CZ  . PHE A  1 507 ? -3.937  -25.828 -13.131 1.000 27.337 0 530  PHE A CZ  1 ? 
ATOM   4082 N  N   . THR A  1 508 ? -5.140  -29.108 -17.789 1.000 33.558 0 531  THR A N   1 ? 
ATOM   4083 C  CA  . THR A  1 508 ? -5.967  -28.404 -18.760 1.000 33.523 0 531  THR A CA  1 ? 
ATOM   4084 C  C   . THR A  1 508 ? -6.762  -27.267 -18.120 1.000 32.669 0 531  THR A C   1 ? 
ATOM   4085 O  O   . THR A  1 508 ? -7.338  -27.420 -17.038 1.000 32.587 0 531  THR A O   1 ? 
ATOM   4086 C  CB  . THR A  1 508 ? -6.926  -29.388 -19.440 1.000 36.924 0 531  THR A CB  1 ? 
ATOM   4087 O  OG1 . THR A  1 508 ? -7.665  -30.118 -18.454 1.000 33.519 0 531  THR A OG1 1 ? 
ATOM   4088 C  CG2 . THR A  1 508 ? -6.208  -30.394 -20.311 1.000 35.768 0 531  THR A CG2 1 ? 
ATOM   4089 N  N   . PRO A  1 509 ? -6.938  -26.130 -18.811 1.000 31.471 0 532  PRO A N   1 ? 
ATOM   4090 C  CA  . PRO A  1 509 ? -7.970  -25.173 -18.413 1.000 33.711 0 532  PRO A CA  1 ? 
ATOM   4091 C  C   . PRO A  1 509 ? -9.352  -25.719 -18.774 1.000 33.797 0 532  PRO A C   1 ? 
ATOM   4092 O  O   . PRO A  1 509 ? -9.459  -26.745 -19.449 1.000 31.441 0 532  PRO A O   1 ? 
ATOM   4093 C  CB  . PRO A  1 509 ? -7.612  -23.956 -19.273 1.000 34.186 0 532  PRO A CB  1 ? 
ATOM   4094 C  CG  . PRO A  1 509 ? -7.089  -24.561 -20.540 1.000 30.978 0 532  PRO A CG  1 ? 
ATOM   4095 C  CD  . PRO A  1 509 ? -6.251  -25.724 -20.054 1.000 33.284 0 532  PRO A CD  1 ? 
ATOM   4096 N  N   . GLY A  1 510 ? -10.407 -25.014 -18.362 1.000 37.572 0 533  GLY A N   1 ? 
ATOM   4097 C  CA  . GLY A  1 510 ? -11.769 -25.347 -18.771 1.000 37.163 0 533  GLY A CA  1 ? 
ATOM   4098 C  C   . GLY A  1 510 ? -12.234 -26.728 -18.306 1.000 37.893 0 533  GLY A C   1 ? 
ATOM   4099 O  O   . GLY A  1 510 ? -13.125 -27.318 -18.908 1.000 32.726 0 533  GLY A O   1 ? 
ATOM   4100 N  N   . ALA A  1 511 ? -11.647 -27.252 -17.222 1.000 32.899 0 534  ALA A N   1 ? 
ATOM   4101 C  CA  . ALA A  1 511 ? -12.030 -28.557 -16.711 1.000 29.371 0 534  ALA A CA  1 ? 
ATOM   4102 C  C   . ALA A  1 511 ? -11.737 -28.606 -15.221 1.000 28.773 0 534  ALA A C   1 ? 
ATOM   4103 O  O   . ALA A  1 511 ? -10.769 -27.984 -14.771 1.000 29.339 0 534  ALA A O   1 ? 
ATOM   4104 C  CB  . ALA A  1 511 ? -11.277 -29.641 -17.414 1.000 28.889 0 534  ALA A CB  1 ? 
ATOM   4105 N  N   . TRP A  1 512 ? -12.556 -29.409 -14.520 1.000 27.047 0 535  TRP A N   1 ? 
ATOM   4106 C  CA  . TRP A  1 512 ? -12.326 -29.743 -13.128 1.000 26.322 0 535  TRP A CA  1 ? 
ATOM   4107 C  C   . TRP A  1 512 ? -11.156 -30.715 -13.000 1.000 27.867 0 535  TRP A C   1 ? 
ATOM   4108 O  O   . TRP A  1 512 ? -10.977 -31.607 -13.837 1.000 25.124 0 535  TRP A O   1 ? 
ATOM   4109 C  CB  . TRP A  1 512 ? -13.611 -30.316 -12.521 1.000 23.842 0 535  TRP A CB  1 ? 
ATOM   4110 C  CG  . TRP A  1 512 ? -14.651 -29.251 -12.313 1.000 22.114 0 535  TRP A CG  1 ? 
ATOM   4111 C  CD1 . TRP A  1 512 ? -15.795 -29.070 -13.040 1.000 22.835 0 535  TRP A CD1 1 ? 
ATOM   4112 C  CD2 . TRP A  1 512 ? -14.666 -28.239 -11.284 1.000 23.206 0 535  TRP A CD2 1 ? 
ATOM   4113 N  NE1 . TRP A  1 512 ? -16.498 -27.994 -12.558 1.000 25.788 0 535  TRP A NE1 1 ? 
ATOM   4114 C  CE2 . TRP A  1 512 ? -15.853 -27.477 -11.469 1.000 22.939 0 535  TRP A CE2 1 ? 
ATOM   4115 C  CE3 . TRP A  1 512 ? -13.823 -27.928 -10.205 1.000 23.860 0 535  TRP A CE3 1 ? 
ATOM   4116 C  CZ2 . TRP A  1 512 ? -16.190 -26.391 -10.656 1.000 24.066 0 535  TRP A CZ2 1 ? 
ATOM   4117 C  CZ3 . TRP A  1 512 ? -14.160 -26.859 -9.397  1.000 23.087 0 535  TRP A CZ3 1 ? 
ATOM   4118 C  CH2 . TRP A  1 512 ? -15.328 -26.101 -9.619  1.000 22.952 0 535  TRP A CH2 1 ? 
ATOM   4119 N  N   . HIS A  1 513 ? -10.329 -30.489 -11.972 1.000 23.728 0 536  HIS A N   1 ? 
ATOM   4120 C  CA  . HIS A  1 513 ? -9.215  -31.375 -11.653 1.000 22.985 0 536  HIS A CA  1 ? 
ATOM   4121 C  C   . HIS A  1 513 ? -9.251  -31.661 -10.163 1.000 25.711 0 536  HIS A C   1 ? 
ATOM   4122 O  O   . HIS A  1 513 ? -9.669  -30.792 -9.380  1.000 25.485 0 536  HIS A O   1 ? 
ATOM   4123 C  CB  . HIS A  1 513 ? -7.887  -30.728 -12.065 1.000 23.547 0 536  HIS A CB  1 ? 
ATOM   4124 C  CG  . HIS A  1 513 ? -7.754  -30.543 -13.534 1.000 24.638 0 536  HIS A CG  1 ? 
ATOM   4125 N  ND1 . HIS A  1 513 ? -7.604  -31.636 -14.371 1.000 25.439 0 536  HIS A ND1 1 ? 
ATOM   4126 C  CD2 . HIS A  1 513 ? -7.777  -29.451 -14.301 1.000 25.617 0 536  HIS A CD2 1 ? 
ATOM   4127 C  CE1 . HIS A  1 513 ? -7.514  -31.176 -15.631 1.000 28.158 0 536  HIS A CE1 1 ? 
ATOM   4128 N  NE2 . HIS A  1 513 ? -7.637  -29.859 -15.619 1.000 25.913 0 536  HIS A NE2 1 ? 
ATOM   4129 N  N   . GLU A  1 514 ? -8.852  -32.875 -9.778  1.000 25.443 0 537  GLU A N   1 ? 
ATOM   4130 C  CA  . GLU A  1 514 ? -8.721  -33.253 -8.374  1.000 26.896 0 537  GLU A CA  1 ? 
ATOM   4131 C  C   . GLU A  1 514 ? -7.239  -33.362 -8.049  1.000 26.758 0 537  GLU A C   1 ? 
ATOM   4132 O  O   . GLU A  1 514 ? -6.522  -34.069 -8.768  1.000 24.193 0 537  GLU A O   1 ? 
ATOM   4133 C  CB  . GLU A  1 514 ? -9.271  -34.648 -8.047  1.000 35.118 0 537  GLU A CB  1 ? 
ATOM   4134 C  CG  . GLU A  1 514 ? -10.752 -34.732 -7.715  1.000 49.990 0 537  GLU A CG  1 ? 
ATOM   4135 C  CD  . GLU A  1 514 ? -11.080 -35.645 -6.528  1.000 61.475 0 537  GLU A CD  1 ? 
ATOM   4136 O  OE1 . GLU A  1 514 ? -10.450 -36.737 -6.402  1.000 46.165 0 537  GLU A OE1 1 ? 
ATOM   4137 O  OE2 . GLU A  1 514 ? -11.972 -35.266 -5.711  1.000 57.529 0 537  GLU A OE2 1 ? 
ATOM   4138 N  N   . ILE A  1 515 ? -6.817  -32.735 -6.954  1.000 23.817 0 538  ILE A N   1 ? 
ATOM   4139 C  CA  . ILE A  1 515 ? -5.475  -32.970 -6.395  1.000 27.009 0 538  ILE A CA  1 ? 
ATOM   4140 C  C   . ILE A  1 515 ? -5.603  -33.702 -5.056  1.000 29.268 0 538  ILE A C   1 ? 
ATOM   4141 O  O   . ILE A  1 515 ? -6.463  -33.377 -4.234  1.000 26.413 0 538  ILE A O   1 ? 
ATOM   4142 C  CB  . ILE A  1 515 ? -4.702  -31.641 -6.288  1.000 28.632 0 538  ILE A CB  1 ? 
ATOM   4143 C  CG1 . ILE A  1 515 ? -4.296  -31.152 -7.681  1.000 28.034 0 538  ILE A CG1 1 ? 
ATOM   4144 C  CG2 . ILE A  1 515 ? -3.480  -31.728 -5.374  1.000 27.341 0 538  ILE A CG2 1 ? 
ATOM   4145 C  CD1 . ILE A  1 515 ? -4.026  -29.703 -7.763  1.000 31.576 0 538  ILE A CD1 1 ? 
ATOM   4146 N  N   . SER A  1 516 ? -4.697  -34.663 -4.830  1.000 24.002 0 539  SER A N   1 ? 
ATOM   4147 C  CA  . SER A  1 516 ? -4.532  -35.400 -3.586  1.000 26.186 0 539  SER A CA  1 ? 
ATOM   4148 C  C   . SER A  1 516 ? -3.172  -35.037 -3.000  1.000 26.573 0 539  SER A C   1 ? 
ATOM   4149 O  O   . SER A  1 516 ? -2.199  -34.968 -3.743  1.000 26.494 0 539  SER A O   1 ? 
ATOM   4150 C  CB  . SER A  1 516 ? -4.514  -36.910 -3.773  1.000 32.882 0 539  SER A CB  1 ? 
ATOM   4151 O  OG  . SER A  1 516 ? -5.769  -37.402 -4.219  1.000 48.763 0 539  SER A OG  1 ? 
ATOM   4152 N  N   . LEU A  1 517 ? -3.137  -34.914 -1.671  1.000 27.398 0 540  LEU A N   1 ? 
ATOM   4153 C  CA  . LEU A  1 517 ? -1.936  -34.753 -0.873  1.000 27.779 0 540  LEU A CA  1 ? 
ATOM   4154 C  C   . LEU A  1 517 ? -1.934  -35.855 0.165   1.000 26.376 0 540  LEU A C   1 ? 
ATOM   4155 O  O   . LEU A  1 517 ? -2.793  -35.900 1.056   1.000 24.264 0 540  LEU A O   1 ? 
ATOM   4156 C  CB  . LEU A  1 517 ? -1.996  -33.402 -0.158  1.000 31.867 0 540  LEU A CB  1 ? 
ATOM   4157 C  CG  . LEU A  1 517 ? -2.215  -32.218 -1.093  1.000 35.386 0 540  LEU A CG  1 ? 
ATOM   4158 C  CD1 . LEU A  1 517 ? -2.543  -30.964 -0.311  1.000 37.976 0 540  LEU A CD1 1 ? 
ATOM   4159 C  CD2 . LEU A  1 517 ? -0.983  -31.995 -1.949  1.000 40.030 0 540  LEU A CD2 1 ? 
ATOM   4160 N  N   . LEU A  1 518 ? -0.963  -36.761 0.033   1.000 25.744 0 541  LEU A N   1 ? 
ATOM   4161 C  CA  . LEU A  1 518 ? -0.805  -37.845 0.980   1.000 26.002 0 541  LEU A CA  1 ? 
ATOM   4162 C  C   . LEU A  1 518 ? 0.462   -37.561 1.778   1.000 27.259 0 541  LEU A C   1 ? 
ATOM   4163 O  O   . LEU A  1 518 ? 1.528   -37.558 1.189   1.000 26.174 0 541  LEU A O   1 ? 
ATOM   4164 C  CB  . LEU A  1 518 ? -0.667  -39.152 0.185   1.000 32.326 0 541  LEU A CB  1 ? 
ATOM   4165 C  CG  . LEU A  1 518 ? -0.401  -40.391 1.032   1.000 36.424 0 541  LEU A CG  1 ? 
ATOM   4166 C  CD1 . LEU A  1 518 ? -1.564  -40.649 1.945   1.000 39.462 0 541  LEU A CD1 1 ? 
ATOM   4167 C  CD2 . LEU A  1 518 ? -0.114  -41.617 0.145   1.000 43.201 0 541  LEU A CD2 1 ? 
ATOM   4168 N  N   . TRP A  1 519 ? 0.332   -37.155 3.051   1.000 27.634 0 542  TRP A N   1 ? 
ATOM   4169 C  CA  . TRP A  1 519 ? 1.509   -36.782 3.815   1.000 26.252 0 542  TRP A CA  1 ? 
ATOM   4170 C  C   . TRP A  1 519 ? 1.790   -37.846 4.873   1.000 23.771 0 542  TRP A C   1 ? 
ATOM   4171 O  O   . TRP A  1 519 ? 0.904   -38.522 5.401   1.000 24.176 0 542  TRP A O   1 ? 
ATOM   4172 C  CB  . TRP A  1 519 ? 1.425   -35.360 4.424   1.000 26.620 0 542  TRP A CB  1 ? 
ATOM   4173 C  CG  . TRP A  1 519 ? 0.456   -35.241 5.571   1.000 24.300 0 542  TRP A CG  1 ? 
ATOM   4174 C  CD1 . TRP A  1 519 ? 0.766   -35.275 6.898   1.000 25.147 0 542  TRP A CD1 1 ? 
ATOM   4175 C  CD2 . TRP A  1 519 ? -0.978  -35.026 5.489   1.000 23.068 0 542  TRP A CD2 1 ? 
ATOM   4176 N  NE1 . TRP A  1 519 ? -0.378  -35.149 7.649   1.000 26.853 0 542  TRP A NE1 1 ? 
ATOM   4177 C  CE2 . TRP A  1 519 ? -1.456  -34.968 6.813   1.000 24.683 0 542  TRP A CE2 1 ? 
ATOM   4178 C  CE3 . TRP A  1 519 ? -1.879  -34.847 4.436   1.000 23.273 0 542  TRP A CE3 1 ? 
ATOM   4179 C  CZ2 . TRP A  1 519 ? -2.806  -34.774 7.105   1.000 25.288 0 542  TRP A CZ2 1 ? 
ATOM   4180 C  CZ3 . TRP A  1 519 ? -3.204  -34.627 4.718   1.000 22.456 0 542  TRP A CZ3 1 ? 
ATOM   4181 C  CH2 . TRP A  1 519 ? -3.661  -34.597 6.037   1.000 23.440 0 542  TRP A CH2 1 ? 
ATOM   4182 N  N   A GLN A  1 520 ? 3.083   -38.023 5.136   0.500 26.128 0 543  GLN A N   1 ? 
ATOM   4183 N  N   B GLN A  1 520 ? 3.080   -38.009 5.137   0.500 27.582 0 543  GLN A N   1 ? 
ATOM   4184 C  CA  A GLN A  1 520 ? 3.565   -38.924 6.166   0.500 26.960 0 543  GLN A CA  1 ? 
ATOM   4185 C  CA  B GLN A  1 520 ? 3.538   -38.878 6.197   0.500 29.825 0 543  GLN A CA  1 ? 
ATOM   4186 C  C   A GLN A  1 520 ? 4.978   -38.457 6.502   0.500 29.451 0 543  GLN A C   1 ? 
ATOM   4187 C  C   B GLN A  1 520 ? 4.972   -38.467 6.508   0.500 31.198 0 543  GLN A C   1 ? 
ATOM   4188 O  O   A GLN A  1 520 ? 5.799   -38.280 5.609   0.500 29.584 0 543  GLN A O   1 ? 
ATOM   4189 O  O   B GLN A  1 520 ? 5.798   -38.362 5.608   0.500 31.485 0 543  GLN A O   1 ? 
ATOM   4190 C  CB  A GLN A  1 520 ? 3.533   -40.386 5.706   0.500 27.747 0 543  GLN A CB  1 ? 
ATOM   4191 C  CB  B GLN A  1 520 ? 3.433   -40.354 5.813   0.500 32.937 0 543  GLN A CB  1 ? 
ATOM   4192 C  CG  A GLN A  1 520 ? 3.568   -41.418 6.841   0.500 28.746 0 543  GLN A CG  1 ? 
ATOM   4193 C  CG  B GLN A  1 520 ? 3.922   -41.286 6.916   0.500 37.259 0 543  GLN A CG  1 ? 
ATOM   4194 C  CD  A GLN A  1 520 ? 4.955   -41.832 7.289   0.500 30.256 0 543  GLN A CD  1 ? 
ATOM   4195 C  CD  B GLN A  1 520 ? 3.458   -42.711 6.746   0.500 39.604 0 543  GLN A CD  1 ? 
ATOM   4196 O  OE1 A GLN A  1 520 ? 5.318   -41.725 8.460   0.500 37.406 0 543  GLN A OE1 1 ? 
ATOM   4197 O  OE1 B GLN A  1 520 ? 3.706   -43.345 5.723   0.500 44.578 0 543  GLN A OE1 1 ? 
ATOM   4198 N  NE2 A GLN A  1 520 ? 5.727   -42.372 6.368   0.500 28.209 0 543  GLN A NE2 1 ? 
ATOM   4199 N  NE2 B GLN A  1 520 ? 2.783   -43.225 7.764   0.500 40.665 0 543  GLN A NE2 1 ? 
ATOM   4200 N  N   . GLY A  1 521 ? 5.231   -38.185 7.784   1.000 32.998 0 544  GLY A N   1 ? 
ATOM   4201 C  CA  . GLY A  1 521 ? 6.520   -37.651 8.200   1.000 33.849 0 544  GLY A CA  1 ? 
ATOM   4202 C  C   . GLY A  1 521 ? 6.845   -36.324 7.532   1.000 36.302 0 544  GLY A C   1 ? 
ATOM   4203 O  O   . GLY A  1 521 ? 6.070   -35.360 7.567   1.000 40.973 0 544  GLY A O   1 ? 
ATOM   4204 N  N   . GLY A  1 522 ? 8.031   -36.285 6.927   1.000 29.549 0 545  GLY A N   1 ? 
ATOM   4205 C  CA  . GLY A  1 522 ? 8.518   -35.077 6.310   1.000 28.918 0 545  GLY A CA  1 ? 
ATOM   4206 C  C   . GLY A  1 522 ? 8.344   -35.065 4.795   1.000 26.196 0 545  GLY A C   1 ? 
ATOM   4207 O  O   . GLY A  1 522 ? 9.049   -34.311 4.118   1.000 26.623 0 545  GLY A O   1 ? 
ATOM   4208 N  N   . GLN A  1 523 ? 7.372   -35.836 4.263   1.000 26.215 0 546  GLN A N   1 ? 
ATOM   4209 C  CA  . GLN A  1 523 ? 7.125   -35.852 2.824   1.000 28.856 0 546  GLN A CA  1 ? 
ATOM   4210 C  C   . GLN A  1 523 ? 5.626   -35.933 2.511   1.000 22.534 0 546  GLN A C   1 ? 
ATOM   4211 O  O   . GLN A  1 523 ? 4.884   -36.578 3.251   1.000 25.090 0 546  GLN A O   1 ? 
ATOM   4212 C  CB  . GLN A  1 523 ? 7.775   -37.092 2.191   1.000 32.949 0 546  GLN A CB  1 ? 
ATOM   4213 C  CG  . GLN A  1 523 ? 9.296   -37.019 2.189   1.000 43.078 0 546  GLN A CG  1 ? 
ATOM   4214 C  CD  . GLN A  1 523 ? 9.867   -38.017 1.205   1.000 60.854 0 546  GLN A CD  1 ? 
ATOM   4215 O  OE1 . GLN A  1 523 ? 9.821   -39.224 1.427   1.000 70.413 0 546  GLN A OE1 1 ? 
ATOM   4216 N  NE2 . GLN A  1 523 ? 10.364  -37.533 0.078   1.000 64.216 0 546  GLN A NE2 1 ? 
ATOM   4217 N  N   . ALA A  1 524 ? 5.243   -35.336 1.382   1.000 24.848 0 547  ALA A N   1 ? 
ATOM   4218 C  CA  . ALA A  1 524 ? 3.888   -35.467 0.867   1.000 27.690 0 547  ALA A CA  1 ? 
ATOM   4219 C  C   . ALA A  1 524 ? 3.926   -35.875 -0.607  1.000 29.050 0 547  ALA A C   1 ? 
ATOM   4220 O  O   . ALA A  1 524 ? 4.643   -35.270 -1.398  1.000 33.924 0 547  ALA A O   1 ? 
ATOM   4221 C  CB  . ALA A  1 524 ? 3.146   -34.152 1.045   1.000 29.109 0 547  ALA A CB  1 ? 
ATOM   4222 N  N   . VAL A  1 525 ? 3.138   -36.892 -0.958  1.000 26.265 0 548  VAL A N   1 ? 
ATOM   4223 C  CA  . VAL A  1 525 ? 2.983   -37.270 -2.353  1.000 29.707 0 548  VAL A CA  1 ? 
ATOM   4224 C  C   . VAL A  1 525 ? 1.754   -36.543 -2.904  1.000 26.034 0 548  VAL A C   1 ? 
ATOM   4225 O  O   . VAL A  1 525 ? 0.679   -36.720 -2.340  1.000 27.018 0 548  VAL A O   1 ? 
ATOM   4226 C  CB  . VAL A  1 525 ? 2.773   -38.788 -2.465  1.000 31.299 0 548  VAL A CB  1 ? 
ATOM   4227 C  CG1 . VAL A  1 525 ? 2.441   -39.192 -3.897  1.000 36.017 0 548  VAL A CG1 1 ? 
ATOM   4228 C  CG2 . VAL A  1 525 ? 3.967   -39.563 -1.929  1.000 36.309 0 548  VAL A CG2 1 ? 
ATOM   4229 N  N   . VAL A  1 526 ? 1.947   -35.802 -3.994  1.000 26.427 0 549  VAL A N   1 ? 
ATOM   4230 C  CA  . VAL A  1 526 ? 0.916   -35.054 -4.686  1.000 28.967 0 549  VAL A CA  1 ? 
ATOM   4231 C  C   . VAL A  1 526 ? 0.481   -35.854 -5.916  1.000 31.372 0 549  VAL A C   1 ? 
ATOM   4232 O  O   . VAL A  1 526 ? 1.331   -36.299 -6.684  1.000 32.189 0 549  VAL A O   1 ? 
ATOM   4233 C  CB  . VAL A  1 526 ? 1.436   -33.665 -5.077  1.000 28.531 0 549  VAL A CB  1 ? 
ATOM   4234 C  CG1 . VAL A  1 526 ? 0.355   -32.827 -5.746  1.000 29.046 0 549  VAL A CG1 1 ? 
ATOM   4235 C  CG2 . VAL A  1 526 ? 2.025   -32.923 -3.885  1.000 32.896 0 549  VAL A CG2 1 ? 
ATOM   4236 N  N   . SER A  1 527 ? -0.834  -36.034 -6.080  1.000 27.500 0 550  SER A N   1 ? 
ATOM   4237 C  CA  . SER A  1 527 ? -1.425  -36.683 -7.251  1.000 30.832 0 550  SER A CA  1 ? 
ATOM   4238 C  C   . SER A  1 527 ? -2.360  -35.691 -7.937  1.000 31.399 0 550  SER A C   1 ? 
ATOM   4239 O  O   . SER A  1 527 ? -2.985  -34.877 -7.252  1.000 27.010 0 550  SER A O   1 ? 
ATOM   4240 C  CB  . SER A  1 527 ? -2.179  -37.943 -6.905  1.000 30.426 0 550  SER A CB  1 ? 
ATOM   4241 O  OG  . SER A  1 527 ? -1.369  -38.876 -6.188  1.000 35.062 0 550  SER A OG  1 ? 
ATOM   4242 N  N   . LEU A  1 528 ? -2.453  -35.812 -9.266  1.000 27.925 0 551  LEU A N   1 ? 
ATOM   4243 C  CA  . LEU A  1 528 ? -3.334  -35.019 -10.095 1.000 29.464 0 551  LEU A CA  1 ? 
ATOM   4244 C  C   . LEU A  1 528 ? -4.217  -35.969 -10.883 1.000 32.957 0 551  LEU A C   1 ? 
ATOM   4245 O  O   . LEU A  1 528 ? -3.692  -36.807 -11.614 1.000 31.848 0 551  LEU A O   1 ? 
ATOM   4246 C  CB  . LEU A  1 528 ? -2.485  -34.146 -11.004 1.000 29.979 0 551  LEU A CB  1 ? 
ATOM   4247 C  CG  . LEU A  1 528 ? -3.224  -33.374 -12.092 1.000 30.074 0 551  LEU A CG  1 ? 
ATOM   4248 C  CD1 . LEU A  1 528 ? -4.224  -32.384 -11.493 1.000 32.344 0 551  LEU A CD1 1 ? 
ATOM   4249 C  CD2 . LEU A  1 528 ? -2.219  -32.653 -12.967 1.000 30.284 0 551  LEU A CD2 1 ? 
ATOM   4250 N  N   . ASP A  1 529 ? -5.539  -35.891 -10.652 1.000 29.857 0 552  ASP A N   1 ? 
ATOM   4251 C  CA  . ASP A  1 529 ? -6.508  -36.733 -11.345 1.000 31.939 0 552  ASP A CA  1 ? 
ATOM   4252 C  C   . ASP A  1 529 ? -6.121  -38.203 -11.274 1.000 37.671 0 552  ASP A C   1 ? 
ATOM   4253 O  O   . ASP A  1 529 ? -6.163  -38.908 -12.272 1.000 38.654 0 552  ASP A O   1 ? 
ATOM   4254 C  CB  . ASP A  1 529 ? -6.691  -36.245 -12.777 1.000 32.751 0 552  ASP A CB  1 ? 
ATOM   4255 C  CG  . ASP A  1 529 ? -7.287  -34.844 -12.844 1.000 34.010 0 552  ASP A CG  1 ? 
ATOM   4256 O  OD1 . ASP A  1 529 ? -8.185  -34.547 -12.012 1.000 34.330 0 552  ASP A OD1 1 ? 
ATOM   4257 O  OD2 . ASP A  1 529 ? -6.896  -34.075 -13.731 1.000 32.118 0 552  ASP A OD2 1 ? 
ATOM   4258 N  N   . GLY A  1 530 ? -5.764  -38.672 -10.081 1.000 36.047 0 553  GLY A N   1 ? 
ATOM   4259 C  CA  . GLY A  1 530 ? -5.551  -40.092 -9.851  1.000 37.514 0 553  GLY A CA  1 ? 
ATOM   4260 C  C   . GLY A  1 530 ? -4.134  -40.590 -10.178 1.000 39.005 0 553  GLY A C   1 ? 
ATOM   4261 O  O   . GLY A  1 530 ? -3.851  -41.762 -9.930  1.000 40.332 0 553  GLY A O   1 ? 
ATOM   4262 N  N   . LYS A  1 531 ? -3.263  -39.735 -10.728 1.000 35.666 0 554  LYS A N   1 ? 
ATOM   4263 C  CA  . LYS A  1 531 ? -1.901  -40.125 -11.074 1.000 42.418 0 554  LYS A CA  1 ? 
ATOM   4264 C  C   . LYS A  1 531 ? -0.882  -39.344 -10.247 1.000 38.717 0 554  LYS A C   1 ? 
ATOM   4265 O  O   . LYS A  1 531 ? -0.867  -38.114 -10.251 1.000 37.778 0 554  LYS A O   1 ? 
ATOM   4266 C  CB  . LYS A  1 531 ? -1.522  -39.809 -12.526 1.000 50.791 0 554  LYS A CB  1 ? 
ATOM   4267 C  CG  . LYS A  1 531 ? -2.492  -40.255 -13.611 1.000 66.534 0 554  LYS A CG  1 ? 
ATOM   4268 C  CD  . LYS A  1 531 ? -2.199  -39.605 -14.954 1.000 73.603 0 554  LYS A CD  1 ? 
ATOM   4269 C  CE  . LYS A  1 531 ? -3.452  -39.262 -15.732 1.000 81.305 0 554  LYS A CE  1 ? 
ATOM   4270 N  NZ  . LYS A  1 531 ? -4.173  -40.484 -16.154 1.000 85.554 0 554  LYS A NZ  1 ? 
ATOM   4271 N  N   . LYS A  1 532 ? 0.076   -40.073 -9.678  1.000 37.912 0 555  LYS A N   1 ? 
ATOM   4272 C  CA  . LYS A  1 532 ? 1.139   -39.430 -8.934  1.000 38.513 0 555  LYS A CA  1 ? 
ATOM   4273 C  C   . LYS A  1 532 ? 1.762   -38.349 -9.802  1.000 32.078 0 555  LYS A C   1 ? 
ATOM   4274 O  O   . LYS A  1 532 ? 2.022   -38.560 -10.977 1.000 39.322 0 555  LYS A O   1 ? 
ATOM   4275 C  CB  . LYS A  1 532 ? 2.156   -40.464 -8.437  1.000 41.386 0 555  LYS A CB  1 ? 
ATOM   4276 C  CG  . LYS A  1 532 ? 3.398   -39.828 -7.840  1.000 48.307 0 555  LYS A CG  1 ? 
ATOM   4277 C  CD  . LYS A  1 532 ? 4.333   -40.788 -7.146  1.000 52.955 0 555  LYS A CD  1 ? 
ATOM   4278 C  CE  . LYS A  1 532 ? 5.537   -40.041 -6.616  1.000 54.130 0 555  LYS A CE  1 ? 
ATOM   4279 N  NZ  . LYS A  1 532 ? 6.376   -40.925 -5.783  1.000 59.075 0 555  LYS A NZ  1 ? 
ATOM   4280 N  N   . ALA A  1 533 ? 2.002   -37.172 -9.226  1.000 28.524 0 556  ALA A N   1 ? 
ATOM   4281 C  CA  . ALA A  1 533 ? 2.524   -36.045 -9.976  1.000 28.038 0 556  ALA A CA  1 ? 
ATOM   4282 C  C   . ALA A  1 533 ? 3.886   -35.593 -9.448  1.000 32.041 0 556  ALA A C   1 ? 
ATOM   4283 O  O   . ALA A  1 533 ? 4.681   -35.011 -10.183 1.000 31.284 0 556  ALA A O   1 ? 
ATOM   4284 C  CB  . ALA A  1 533 ? 1.539   -34.931 -9.912  1.000 32.400 0 556  ALA A CB  1 ? 
ATOM   4285 N  N   . GLY A  1 534 ? 4.141   -35.784 -8.154  1.000 33.428 0 557  GLY A N   1 ? 
ATOM   4286 C  CA  . GLY A  1 534 ? 5.392   -35.303 -7.591  1.000 35.004 0 557  GLY A CA  1 ? 
ATOM   4287 C  C   . GLY A  1 534 ? 5.412   -35.458 -6.075  1.000 33.276 0 557  GLY A C   1 ? 
ATOM   4288 O  O   . GLY A  1 534 ? 4.508   -36.054 -5.507  1.000 32.007 0 557  GLY A O   1 ? 
ATOM   4289 N  N   A THR A  1 535 ? 6.478   -34.965 -5.427  0.500 33.709 0 558  THR A N   1 ? 
ATOM   4290 N  N   B THR A  1 535 ? 6.463   -34.913 -5.464  0.500 33.940 0 558  THR A N   1 ? 
ATOM   4291 C  CA  A THR A  1 535 ? 6.626   -35.068 -3.979  0.500 35.031 0 558  THR A CA  1 ? 
ATOM   4292 C  CA  B THR A  1 535 ? 6.647   -34.989 -4.028  0.500 35.576 0 558  THR A CA  1 ? 
ATOM   4293 C  C   A THR A  1 535 ? 7.085   -33.718 -3.427  0.500 35.600 0 558  THR A C   1 ? 
ATOM   4294 C  C   B THR A  1 535 ? 6.891   -33.574 -3.516  0.500 35.376 0 558  THR A C   1 ? 
ATOM   4295 O  O   A THR A  1 535 ? 7.895   -33.037 -4.053  0.500 38.496 0 558  THR A O   1 ? 
ATOM   4296 O  O   B THR A  1 535 ? 7.287   -32.688 -4.277  0.500 37.065 0 558  THR A O   1 ? 
ATOM   4297 C  CB  A THR A  1 535 ? 7.611   -36.178 -3.560  0.500 35.825 0 558  THR A CB  1 ? 
ATOM   4298 C  CB  B THR A  1 535 ? 7.786   -35.957 -3.674  0.500 37.148 0 558  THR A CB  1 ? 
ATOM   4299 O  OG1 A THR A  1 535 ? 7.342   -37.378 -4.285  0.500 33.244 0 558  THR A OG1 1 ? 
ATOM   4300 O  OG1 B THR A  1 535 ? 8.934   -35.506 -4.389  0.500 38.591 0 558  THR A OG1 1 ? 
ATOM   4301 C  CG2 A THR A  1 535 ? 7.562   -36.488 -2.075  0.500 35.957 0 558  THR A CG2 1 ? 
ATOM   4302 C  CG2 B THR A  1 535 ? 7.489   -37.398 -4.030  0.500 36.049 0 558  THR A CG2 1 ? 
ATOM   4303 N  N   . LEU A  1 536 ? 6.583   -33.369 -2.233  1.000 32.539 0 559  LEU A N   1 ? 
ATOM   4304 C  CA  . LEU A  1 536 ? 6.949   -32.147 -1.529  1.000 32.494 0 559  LEU A CA  1 ? 
ATOM   4305 C  C   . LEU A  1 536 ? 7.703   -32.518 -0.260  1.000 29.040 0 559  LEU A C   1 ? 
ATOM   4306 O  O   . LEU A  1 536 ? 7.286   -33.421 0.458   1.000 29.146 0 559  LEU A O   1 ? 
ATOM   4307 C  CB  . LEU A  1 536 ? 5.662   -31.419 -1.142  1.000 31.976 0 559  LEU A CB  1 ? 
ATOM   4308 C  CG  . LEU A  1 536 ? 4.873   -30.854 -2.318  1.000 29.154 0 559  LEU A CG  1 ? 
ATOM   4309 C  CD1 . LEU A  1 536 ? 3.531   -30.313 -1.848  1.000 28.885 0 559  LEU A CD1 1 ? 
ATOM   4310 C  CD2 . LEU A  1 536 ? 5.686   -29.795 -3.027  1.000 27.642 0 559  LEU A CD2 1 ? 
ATOM   4311 N  N   . LYS A  1 537 ? 8.838   -31.862 -0.031  1.000 28.457 0 560  LYS A N   1 ? 
ATOM   4312 C  CA  . LYS A  1 537 ? 9.490   -31.959 1.253   1.000 29.965 0 560  LYS A CA  1 ? 
ATOM   4313 C  C   . LYS A  1 537 ? 8.760   -31.052 2.250   1.000 25.277 0 560  LYS A C   1 ? 
ATOM   4314 O  O   . LYS A  1 537 ? 8.358   -29.963 1.891   1.000 23.384 0 560  LYS A O   1 ? 
ATOM   4315 C  CB  . LYS A  1 537 ? 10.941  -31.497 1.112   1.000 32.366 0 560  LYS A CB  1 ? 
ATOM   4316 C  CG  . LYS A  1 537 ? 11.814  -31.843 2.306   1.000 36.544 0 560  LYS A CG  1 ? 
ATOM   4317 C  CD  . LYS A  1 537 ? 13.227  -31.282 2.168   1.000 38.089 0 560  LYS A CD  1 ? 
ATOM   4318 C  CE  . LYS A  1 537 ? 14.095  -31.571 3.371   1.000 37.412 0 560  LYS A CE  1 ? 
ATOM   4319 N  NZ  . LYS A  1 537 ? 15.456  -30.998 3.191   1.000 39.841 0 560  LYS A NZ  1 ? 
ATOM   4320 N  N   . MET A  1 538 ? 8.608   -31.522 3.477   1.000 25.949 0 561  MET A N   1 ? 
ATOM   4321 C  CA  . MET A  1 538 ? 8.094   -30.700 4.563   1.000 25.542 0 561  MET A CA  1 ? 
ATOM   4322 C  C   . MET A  1 538 ? 8.849   -29.388 4.628   1.000 28.364 0 561  MET A C   1 ? 
ATOM   4323 O  O   . MET A  1 538 ? 10.076  -29.386 4.662   1.000 28.812 0 561  MET A O   1 ? 
ATOM   4324 C  CB  . MET A  1 538 ? 8.259   -31.472 5.874   1.000 28.006 0 561  MET A CB  1 ? 
ATOM   4325 C  CG  . MET A  1 538 ? 7.967   -30.679 7.123   1.000 29.661 0 561  MET A CG  1 ? 
ATOM   4326 S  SD  . MET A  1 538 ? 7.785   -31.833 8.481   1.000 33.322 0 561  MET A SD  1 ? 
ATOM   4327 C  CE  . MET A  1 538 ? 6.003   -31.969 8.609   1.000 32.137 0 561  MET A CE  1 ? 
ATOM   4328 N  N   . ALA A  1 539 ? 8.117   -28.276 4.668   1.000 24.834 0 562  ALA A N   1 ? 
ATOM   4329 C  CA  . ALA A  1 539 ? 8.691   -26.950 4.741   1.000 25.731 0 562  ALA A CA  1 ? 
ATOM   4330 C  C   . ALA A  1 539 ? 8.898   -26.525 6.197   1.000 27.146 0 562  ALA A C   1 ? 
ATOM   4331 O  O   . ALA A  1 539 ? 9.788   -25.737 6.470   1.000 31.372 0 562  ALA A O   1 ? 
ATOM   4332 C  CB  . ALA A  1 539 ? 7.791   -25.962 4.051   1.000 29.627 0 562  ALA A CB  1 ? 
ATOM   4333 N  N   . ASN A  1 540 ? 8.032   -26.980 7.104   1.000 27.279 0 563  ASN A N   1 ? 
ATOM   4334 C  CA  . ASN A  1 540 ? 8.146   -26.658 8.520   1.000 26.268 0 563  ASN A CA  1 ? 
ATOM   4335 C  C   . ASN A  1 540 ? 7.655   -27.825 9.337   1.000 26.115 0 563  ASN A C   1 ? 
ATOM   4336 O  O   . ASN A  1 540 ? 6.625   -28.429 9.031   1.000 26.887 0 563  ASN A O   1 ? 
ATOM   4337 C  CB  . ASN A  1 540 ? 7.336   -25.432 8.952   1.000 26.780 0 563  ASN A CB  1 ? 
ATOM   4338 C  CG  . ASN A  1 540 ? 7.806   -24.166 8.301   1.000 24.516 0 563  ASN A CG  1 ? 
ATOM   4339 O  OD1 . ASN A  1 540 ? 8.722   -23.507 8.780   1.000 32.571 0 563  ASN A OD1 1 ? 
ATOM   4340 N  ND2 . ASN A  1 540 ? 7.206   -23.811 7.192   1.000 26.059 0 563  ASN A ND2 1 ? 
ATOM   4341 N  N   . LYS A  1 541 ? 8.405   -28.152 10.392  1.000 26.537 0 564  LYS A N   1 ? 
ATOM   4342 C  CA  . LYS A  1 541 ? 7.975   -29.185 11.327  1.000 25.202 0 564  LYS A CA  1 ? 
ATOM   4343 C  C   . LYS A  1 541 ? 6.791   -28.668 12.139  1.000 25.684 0 564  LYS A C   1 ? 
ATOM   4344 O  O   . LYS A  1 541 ? 6.616   -27.459 12.250  1.000 29.503 0 564  LYS A O   1 ? 
ATOM   4345 C  CB  . LYS A  1 541 ? 9.095   -29.532 12.314  1.000 34.837 0 564  LYS A CB  1 ? 
ATOM   4346 C  CG  . LYS A  1 541 ? 10.415  -29.977 11.696  1.000 47.137 0 564  LYS A CG  1 ? 
ATOM   4347 C  CD  . LYS A  1 541 ? 11.524  -30.106 12.744  1.000 54.138 0 564  LYS A CD  1 ? 
ATOM   4348 C  CE  . LYS A  1 541 ? 12.914  -30.183 12.151  1.000 62.037 0 564  LYS A CE  1 ? 
ATOM   4349 N  NZ  . LYS A  1 541 ? 13.108  -31.464 11.435  1.000 70.631 0 564  LYS A NZ  1 ? 
ATOM   4350 N  N   . SER A  1 542 ? 5.982   -29.592 12.647  1.000 26.970 0 565  SER A N   1 ? 
ATOM   4351 C  CA  . SER A  1 542 ? 4.882   -29.309 13.545  1.000 27.195 0 565  SER A CA  1 ? 
ATOM   4352 C  C   . SER A  1 542 ? 5.007   -30.196 14.778  1.000 27.248 0 565  SER A C   1 ? 
ATOM   4353 O  O   . SER A  1 542 ? 5.248   -31.398 14.671  1.000 23.504 0 565  SER A O   1 ? 
ATOM   4354 C  CB  . SER A  1 542 ? 3.564   -29.554 12.847  1.000 26.361 0 565  SER A CB  1 ? 
ATOM   4355 O  OG  . SER A  1 542 ? 2.477   -29.438 13.740  1.000 25.628 0 565  SER A OG  1 ? 
ATOM   4356 N  N   . PRO A  1 543 ? 4.673   -29.702 15.985  1.000 24.193 0 566  PRO A N   1 ? 
ATOM   4357 C  CA  . PRO A  1 543 ? 4.528   -30.593 17.139  1.000 24.385 0 566  PRO A CA  1 ? 
ATOM   4358 C  C   . PRO A  1 543 ? 3.304   -31.489 17.054  1.000 22.737 0 566  PRO A C   1 ? 
ATOM   4359 O  O   . PRO A  1 543 ? 3.220   -32.496 17.763  1.000 23.744 0 566  PRO A O   1 ? 
ATOM   4360 C  CB  . PRO A  1 543 ? 4.385   -29.626 18.333  1.000 27.370 0 566  PRO A CB  1 ? 
ATOM   4361 C  CG  . PRO A  1 543 ? 3.848   -28.360 17.697  1.000 28.506 0 566  PRO A CG  1 ? 
ATOM   4362 C  CD  . PRO A  1 543 ? 4.495   -28.282 16.335  1.000 27.344 0 566  PRO A CD  1 ? 
ATOM   4363 N  N   . ASN A  1 544 ? 2.346   -31.175 16.159  1.000 23.295 0 567  ASN A N   1 ? 
ATOM   4364 C  CA  . ASN A  1 544 ? 1.074   -31.883 16.206  1.000 23.368 0 567  ASN A CA  1 ? 
ATOM   4365 C  C   . ASN A  1 544 ? 0.722   -32.656 14.926  1.000 21.997 0 567  ASN A C   1 ? 
ATOM   4366 O  O   . ASN A  1 544 ? 0.173   -33.753 15.036  1.000 24.775 0 567  ASN A O   1 ? 
ATOM   4367 C  CB  . ASN A  1 544 ? -0.073  -30.918 16.527  1.000 25.217 0 567  ASN A CB  1 ? 
ATOM   4368 C  CG  . ASN A  1 544 ? 0.191   -30.162 17.810  1.000 26.120 0 567  ASN A CG  1 ? 
ATOM   4369 O  OD1 . ASN A  1 544 ? 0.577   -30.799 18.804  1.000 23.093 0 567  ASN A OD1 1 ? 
ATOM   4370 N  ND2 . ASN A  1 544 ? 0.012   -28.840 17.781  1.000 22.422 0 567  ASN A ND2 1 ? 
ATOM   4371 N  N   . GLY A  1 545 ? 0.913   -32.025 13.766  1.000 22.714 0 568  GLY A N   1 ? 
ATOM   4372 C  CA  . GLY A  1 545 ? 0.406   -32.527 12.496  1.000 25.193 0 568  GLY A CA  1 ? 
ATOM   4373 C  C   . GLY A  1 545 ? -0.404  -31.451 11.775  1.000 24.572 0 568  GLY A C   1 ? 
ATOM   4374 O  O   . GLY A  1 545 ? -0.427  -30.282 12.205  1.000 23.211 0 568  GLY A O   1 ? 
ATOM   4375 N  N   . ALA A  1 546 ? -1.077  -31.876 10.700  1.000 23.408 0 569  ALA A N   1 ? 
ATOM   4376 C  CA  . ALA A  1 546 ? -1.840  -30.969 9.857   1.000 20.271 0 569  ALA A CA  1 ? 
ATOM   4377 C  C   . ALA A  1 546 ? -3.301  -31.072 10.259  1.000 19.415 0 569  ALA A C   1 ? 
ATOM   4378 O  O   . ALA A  1 546 ? -3.827  -32.149 10.508  1.000 20.748 0 569  ALA A O   1 ? 
ATOM   4379 C  CB  . ALA A  1 546 ? -1.665  -31.314 8.391   1.000 21.967 0 569  ALA A CB  1 ? 
ATOM   4380 N  N   . SER A  1 547 ? -3.943  -29.914 10.361  1.000 19.753 0 570  SER A N   1 ? 
ATOM   4381 C  CA  . SER A  1 547 ? -5.354  -29.836 10.720  1.000 18.633 0 570  SER A CA  1 ? 
ATOM   4382 C  C   . SER A  1 547 ? -6.050  -28.756 9.883   1.000 17.197 0 570  SER A C   1 ? 
ATOM   4383 O  O   . SER A  1 547 ? -7.243  -28.512 10.070  1.000 18.328 0 570  SER A O   1 ? 
ATOM   4384 C  CB  . SER A  1 547 ? -5.546  -29.609 12.216  1.000 19.277 0 570  SER A CB  1 ? 
ATOM   4385 O  OG  . SER A  1 547 ? -4.797  -28.474 12.649  1.000 19.389 0 570  SER A OG  1 ? 
ATOM   4386 N  N   . TYR A  1 548 ? -5.355  -28.123 8.954   1.000 17.364 0 571  TYR A N   1 ? 
ATOM   4387 C  CA  . TYR A  1 548 ? -6.002  -27.197 8.035   1.000 19.558 0 571  TYR A CA  1 ? 
ATOM   4388 C  C   . TYR A  1 548 ? -5.446  -27.373 6.642   1.000 20.997 0 571  TYR A C   1 ? 
ATOM   4389 O  O   . TYR A  1 548 ? -4.252  -27.629 6.463   1.000 19.406 0 571  TYR A O   1 ? 
ATOM   4390 C  CB  . TYR A  1 548 ? -5.752  -25.715 8.373   1.000 20.158 0 571  TYR A CB  1 ? 
ATOM   4391 C  CG  . TYR A  1 548 ? -6.688  -25.213 9.459   1.000 17.575 0 571  TYR A CG  1 ? 
ATOM   4392 C  CD1 . TYR A  1 548 ? -6.452  -25.450 10.824  1.000 17.709 0 571  TYR A CD1 1 ? 
ATOM   4393 C  CD2 . TYR A  1 548 ? -7.895  -24.612 9.101   1.000 19.256 0 571  TYR A CD2 1 ? 
ATOM   4394 C  CE1 . TYR A  1 548 ? -7.335  -25.009 11.786  1.000 18.621 0 571  TYR A CE1 1 ? 
ATOM   4395 C  CE2 . TYR A  1 548 ? -8.806  -24.201 10.063  1.000 18.083 0 571  TYR A CE2 1 ? 
ATOM   4396 C  CZ  . TYR A  1 548 ? -8.542  -24.436 11.403  1.000 17.450 0 571  TYR A CZ  1 ? 
ATOM   4397 O  OH  . TYR A  1 548 ? -9.453  -24.083 12.358  1.000 20.460 0 571  TYR A OH  1 ? 
ATOM   4398 N  N   . ILE A  1 549 ? -6.311  -27.104 5.655   1.000 19.025 0 572  ILE A N   1 ? 
ATOM   4399 C  CA  . ILE A  1 549 ? -5.830  -26.740 4.345   1.000 18.326 0 572  ILE A CA  1 ? 
ATOM   4400 C  C   . ILE A  1 549 ? -6.237  -25.292 4.077   1.000 20.182 0 572  ILE A C   1 ? 
ATOM   4401 O  O   . ILE A  1 549 ? -7.339  -24.842 4.418   1.000 19.126 0 572  ILE A O   1 ? 
ATOM   4402 C  CB  . ILE A  1 549 ? -6.303  -27.755 3.286   1.000 19.576 0 572  ILE A CB  1 ? 
ATOM   4403 C  CG1 . ILE A  1 549 ? -5.730  -27.426 1.925   1.000 20.595 0 572  ILE A CG1 1 ? 
ATOM   4404 C  CG2 . ILE A  1 549 ? -7.834  -27.835 3.264   1.000 21.109 0 572  ILE A CG2 1 ? 
ATOM   4405 C  CD1 . ILE A  1 549 ? -5.790  -28.583 0.973   1.000 22.487 0 572  ILE A CD1 1 ? 
ATOM   4406 N  N   . HIS A  1 550 ? -5.286  -24.580 3.483   1.000 18.132 0 573  HIS A N   1 ? 
ATOM   4407 C  CA  . HIS A  1 550 ? -5.357  -23.154 3.206   1.000 20.093 0 573  HIS A CA  1 ? 
ATOM   4408 C  C   . HIS A  1 550 ? -5.081  -22.895 1.725   1.000 22.805 0 573  HIS A C   1 ? 
ATOM   4409 O  O   . HIS A  1 550 ? -4.107  -23.440 1.173   1.000 19.046 0 573  HIS A O   1 ? 
ATOM   4410 C  CB  . HIS A  1 550 ? -4.369  -22.399 4.107   1.000 18.847 0 573  HIS A CB  1 ? 
ATOM   4411 C  CG  . HIS A  1 550 ? -4.366  -20.907 3.949   1.000 18.197 0 573  HIS A CG  1 ? 
ATOM   4412 N  ND1 . HIS A  1 550 ? -3.591  -20.283 2.997   1.000 17.471 0 573  HIS A ND1 1 ? 
ATOM   4413 C  CD2 . HIS A  1 550 ? -4.876  -19.928 4.734   1.000 17.528 0 573  HIS A CD2 1 ? 
ATOM   4414 C  CE1 . HIS A  1 550 ? -3.741  -18.969 3.131   1.000 17.791 0 573  HIS A CE1 1 ? 
ATOM   4415 N  NE2 . HIS A  1 550 ? -4.539  -18.723 4.172   1.000 18.549 0 573  HIS A NE2 1 ? 
ATOM   4416 N  N   . PHE A  1 551 ? -5.964  -22.097 1.083   1.000 18.191 0 574  PHE A N   1 ? 
ATOM   4417 C  CA  . PHE A  1 551 ? -5.866  -21.807 -0.333  1.000 19.011 0 574  PHE A CA  1 ? 
ATOM   4418 C  C   . PHE A  1 551 ? -5.863  -20.301 -0.515  1.000 19.943 0 574  PHE A C   1 ? 
ATOM   4419 O  O   . PHE A  1 551 ? -6.828  -19.662 -0.086  1.000 22.106 0 574  PHE A O   1 ? 
ATOM   4420 C  CB  . PHE A  1 551 ? -7.085  -22.338 -1.125  1.000 18.996 0 574  PHE A CB  1 ? 
ATOM   4421 C  CG  . PHE A  1 551 ? -7.436  -23.782 -0.914  1.000 18.253 0 574  PHE A CG  1 ? 
ATOM   4422 C  CD1 . PHE A  1 551 ? -8.327  -24.151 0.076   1.000 18.646 0 574  PHE A CD1 1 ? 
ATOM   4423 C  CD2 . PHE A  1 551 ? -6.937  -24.777 -1.754  1.000 19.914 0 574  PHE A CD2 1 ? 
ATOM   4424 C  CE1 . PHE A  1 551 ? -8.655  -25.488 0.292   1.000 19.365 0 574  PHE A CE1 1 ? 
ATOM   4425 C  CE2 . PHE A  1 551 ? -7.285  -26.100 -1.551  1.000 19.621 0 574  PHE A CE2 1 ? 
ATOM   4426 C  CZ  . PHE A  1 551 ? -8.170  -26.451 -0.555  1.000 18.961 0 574  PHE A CZ  1 ? 
ATOM   4427 N  N   . ILE A  1 552 ? -4.835  -19.713 -1.134  1.000 17.732 0 575  ILE A N   1 ? 
ATOM   4428 C  CA  . ILE A  1 552 ? -4.890  -18.278 -1.328  1.000 18.256 0 575  ILE A CA  1 ? 
ATOM   4429 C  C   . ILE A  1 552 ? -4.473  -17.916 -2.746  1.000 20.874 0 575  ILE A C   1 ? 
ATOM   4430 O  O   . ILE A  1 552 ? -3.522  -18.476 -3.273  1.000 20.386 0 575  ILE A O   1 ? 
ATOM   4431 C  CB  . ILE A  1 552 ? -4.086  -17.524 -0.270  1.000 19.593 0 575  ILE A CB  1 ? 
ATOM   4432 C  CG1 . ILE A  1 552 ? -4.299  -16.021 -0.430  1.000 19.312 0 575  ILE A CG1 1 ? 
ATOM   4433 C  CG2 . ILE A  1 552 ? -2.595  -17.891 -0.308  1.000 20.653 0 575  ILE A CG2 1 ? 
ATOM   4434 C  CD1 . ILE A  1 552 ? -3.692  -15.177 0.673   1.000 19.929 0 575  ILE A CD1 1 ? 
ATOM   4435 N  N   . SER A  1 553 ? -5.174  -16.939 -3.356  1.000 20.161 0 576  SER A N   1 ? 
ATOM   4436 C  CA  . SER A  1 553 ? -4.817  -16.420 -4.665  1.000 19.671 0 576  SER A CA  1 ? 
ATOM   4437 C  C   . SER A  1 553 ? -3.411  -15.821 -4.631  1.000 21.642 0 576  SER A C   1 ? 
ATOM   4438 O  O   . SER A  1 553 ? -2.959  -15.368 -3.573  1.000 20.660 0 576  SER A O   1 ? 
ATOM   4439 C  CB  . SER A  1 553 ? -5.832  -15.412 -5.142  1.000 19.670 0 576  SER A CB  1 ? 
ATOM   4440 O  OG  . SER A  1 553 ? -5.907  -14.336 -4.231  1.000 18.830 0 576  SER A OG  1 ? 
ATOM   4441 N  N   . THR A  1 554 ? -2.723  -15.870 -5.783  1.000 22.261 0 577  THR A N   1 ? 
ATOM   4442 C  CA  . THR A  1 554 ? -1.347  -15.385 -5.887  1.000 22.654 0 577  THR A CA  1 ? 
ATOM   4443 C  C   . THR A  1 554 ? -1.214  -14.184 -6.815  1.000 25.810 0 577  THR A C   1 ? 
ATOM   4444 O  O   . THR A  1 554 ? -0.156  -13.553 -6.865  1.000 24.488 0 577  THR A O   1 ? 
ATOM   4445 C  CB  . THR A  1 554 ? -0.382  -16.491 -6.324  1.000 24.074 0 577  THR A CB  1 ? 
ATOM   4446 O  OG1 . THR A  1 554 ? -0.786  -17.084 -7.559  1.000 24.187 0 577  THR A OG1 1 ? 
ATOM   4447 C  CG2 . THR A  1 554 ? -0.268  -17.593 -5.304  1.000 25.803 0 577  THR A CG2 1 ? 
ATOM   4448 N  N   . GLY A  1 555 ? -2.278  -13.833 -7.546  1.000 24.141 0 578  GLY A N   1 ? 
ATOM   4449 C  CA  . GLY A  1 555 ? -2.198  -12.739 -8.505  1.000 22.556 0 578  GLY A CA  1 ? 
ATOM   4450 C  C   . GLY A  1 555 ? -1.879  -11.411 -7.829  1.000 25.803 0 578  GLY A C   1 ? 
ATOM   4451 O  O   . GLY A  1 555 ? -2.333  -11.192 -6.707  1.000 24.413 0 578  GLY A O   1 ? 
ATOM   4452 N  N   A SER A  1 556 ? -1.086  -10.559 -8.505  0.500 26.279 0 579  SER A N   1 ? 
ATOM   4453 N  N   B SER A  1 556 ? -1.085  -10.553 -8.495  0.500 23.723 0 579  SER A N   1 ? 
ATOM   4454 C  CA  A SER A  1 556 ? -0.733  -9.237  -8.012  0.500 27.942 0 579  SER A CA  1 ? 
ATOM   4455 C  CA  B SER A  1 556 ? -0.756  -9.237  -7.970  0.500 23.310 0 579  SER A CA  1 ? 
ATOM   4456 C  C   A SER A  1 556 ? -1.575  -8.156  -8.674  0.500 28.043 0 579  SER A C   1 ? 
ATOM   4457 C  C   B SER A  1 556 ? -1.497  -8.141  -8.734  0.500 25.299 0 579  SER A C   1 ? 
ATOM   4458 O  O   A SER A  1 556 ? -1.543  -7.002  -8.247  0.500 28.747 0 579  SER A O   1 ? 
ATOM   4459 O  O   B SER A  1 556 ? -1.354  -6.961  -8.415  0.500 26.346 0 579  SER A O   1 ? 
ATOM   4460 C  CB  A SER A  1 556 ? 0.732   -8.933  -8.220  0.500 33.334 0 579  SER A CB  1 ? 
ATOM   4461 C  CB  B SER A  1 556 ? 0.757   -9.000  -7.942  0.500 24.513 0 579  SER A CB  1 ? 
ATOM   4462 O  OG  A SER A  1 556 ? 1.521   -9.648  -7.294  0.500 38.091 0 579  SER A OG  1 ? 
ATOM   4463 O  OG  B SER A  1 556 ? 1.324   -9.020  -9.247  0.500 23.403 0 579  SER A OG  1 ? 
ATOM   4464 N  N   . GLN A  1 557 ? -2.320  -8.528  -9.721  1.000 26.551 0 580  GLN A N   1 ? 
ATOM   4465 C  CA  . GLN A  1 557 ? -3.269  -7.620  -10.340 1.000 27.647 0 580  GLN A CA  1 ? 
ATOM   4466 C  C   . GLN A  1 557 ? -4.640  -8.295  -10.416 1.000 25.027 0 580  GLN A C   1 ? 
ATOM   4467 O  O   . GLN A  1 557 ? -4.705  -9.519  -10.426 1.000 24.189 0 580  GLN A O   1 ? 
ATOM   4468 C  CB  . GLN A  1 557 ? -2.791  -7.267  -11.755 1.000 31.638 0 580  GLN A CB  1 ? 
ATOM   4469 C  CG  . GLN A  1 557 ? -1.529  -6.423  -11.795 1.000 34.335 0 580  GLN A CG  1 ? 
ATOM   4470 C  CD  . GLN A  1 557 ? -1.694  -5.081  -11.129 1.000 40.849 0 580  GLN A CD  1 ? 
ATOM   4471 O  OE1 . GLN A  1 557 ? -2.719  -4.426  -11.264 1.000 47.304 0 580  GLN A OE1 1 ? 
ATOM   4472 N  NE2 . GLN A  1 557 ? -0.687  -4.666  -10.378 1.000 46.844 0 580  GLN A NE2 1 ? 
ATOM   4473 N  N   . PRO A  1 558 ? -5.764  -7.559  -10.498 1.000 25.348 0 581  PRO A N   1 ? 
ATOM   4474 C  CA  . PRO A  1 558 ? -7.079  -8.203  -10.497 1.000 27.873 0 581  PRO A CA  1 ? 
ATOM   4475 C  C   . PRO A  1 558 ? -7.157  -9.246  -11.605 1.000 27.652 0 581  PRO A C   1 ? 
ATOM   4476 O  O   . PRO A  1 558 ? -6.703  -8.991  -12.721 1.000 24.900 0 581  PRO A O   1 ? 
ATOM   4477 C  CB  . PRO A  1 558 ? -8.054  -7.064  -10.746 1.000 27.456 0 581  PRO A CB  1 ? 
ATOM   4478 C  CG  . PRO A  1 558 ? -7.336  -5.866  -10.192 1.000 27.866 0 581  PRO A CG  1 ? 
ATOM   4479 C  CD  . PRO A  1 558 ? -5.865  -6.089  -10.482 1.000 27.670 0 581  PRO A CD  1 ? 
ATOM   4480 N  N   . ASP A  1 559 ? -7.719  -10.408 -11.271 1.000 22.882 0 582  ASP A N   1 ? 
ATOM   4481 C  CA  . ASP A  1 559 ? -7.708  -11.558 -12.153 1.000 22.691 0 582  ASP A CA  1 ? 
ATOM   4482 C  C   . ASP A  1 559 ? -9.012  -12.344 -12.001 1.000 21.041 0 582  ASP A C   1 ? 
ATOM   4483 O  O   . ASP A  1 559 ? -9.924  -11.952 -11.276 1.000 25.382 0 582  ASP A O   1 ? 
ATOM   4484 C  CB  . ASP A  1 559 ? -6.440  -12.391 -11.964 1.000 22.345 0 582  ASP A CB  1 ? 
ATOM   4485 C  CG  . ASP A  1 559 ? -6.275  -13.008 -10.572 1.000 26.365 0 582  ASP A CG  1 ? 
ATOM   4486 O  OD1 . ASP A  1 559 ? -7.250  -12.938 -9.759  1.000 24.211 0 582  ASP A OD1 1 ? 
ATOM   4487 O  OD2 . ASP A  1 559 ? -5.179  -13.507 -10.292 1.000 25.364 0 582  ASP A OD2 1 ? 
ATOM   4488 N  N   . ALA A  1 560 ? -9.113  -13.448 -12.725 1.000 21.345 0 583  ALA A N   1 ? 
ATOM   4489 C  CA  . ALA A  1 560 ? -10.312 -14.273 -12.676 1.000 23.184 0 583  ALA A CA  1 ? 
ATOM   4490 C  C   . ALA A  1 560 ? -10.177 -15.386 -11.652 1.000 22.282 0 583  ALA A C   1 ? 
ATOM   4491 O  O   . ALA A  1 560 ? -11.167 -15.801 -11.045 1.000 21.996 0 583  ALA A O   1 ? 
ATOM   4492 C  CB  . ALA A  1 560 ? -10.600 -14.831 -14.041 1.000 26.072 0 583  ALA A CB  1 ? 
ATOM   4493 N  N   . GLY A  1 561 ? -8.956  -15.910 -11.505 1.000 22.011 0 584  GLY A N   1 ? 
ATOM   4494 C  CA  . GLY A  1 561 ? -8.672  -16.849 -10.437 1.000 21.560 0 584  GLY A CA  1 ? 
ATOM   4495 C  C   . GLY A  1 561 ? -9.122  -18.265 -10.761 1.000 21.104 0 584  GLY A C   1 ? 
ATOM   4496 O  O   . GLY A  1 561 ? -9.135  -18.685 -11.934 1.000 22.485 0 584  GLY A O   1 ? 
ATOM   4497 N  N   . ILE A  1 562 ? -9.465  -18.991 -9.687  1.000 19.105 0 585  ILE A N   1 ? 
ATOM   4498 C  CA  . ILE A  1 562 ? -9.813  -20.395 -9.739  1.000 19.855 0 585  ILE A CA  1 ? 
ATOM   4499 C  C   . ILE A  1 562 ? -11.129 -20.604 -8.980  1.000 21.391 0 585  ILE A C   1 ? 
ATOM   4500 O  O   . ILE A  1 562 ? -11.508 -19.769 -8.160  1.000 21.055 0 585  ILE A O   1 ? 
ATOM   4501 C  CB  . ILE A  1 562 ? -8.680  -21.299 -9.195  1.000 22.016 0 585  ILE A CB  1 ? 
ATOM   4502 C  CG1 . ILE A  1 562 ? -8.462  -21.143 -7.687  1.000 24.767 0 585  ILE A CG1 1 ? 
ATOM   4503 C  CG2 . ILE A  1 562 ? -7.395  -21.025 -9.986  1.000 23.774 0 585  ILE A CG2 1 ? 
ATOM   4504 C  CD1 . ILE A  1 562 ? -9.409  -21.953 -6.772  1.000 25.538 0 585  ILE A CD1 1 ? 
ATOM   4505 N  N   . LEU A  1 563 ? -11.746 -21.772 -9.217  1.000 19.610 0 586  LEU A N   1 ? 
ATOM   4506 C  CA  . LEU A  1 563 ? -12.928 -22.222 -8.505  1.000 20.486 0 586  LEU A CA  1 ? 
ATOM   4507 C  C   . LEU A  1 563 ? -12.548 -23.419 -7.647  1.000 19.816 0 586  LEU A C   1 ? 
ATOM   4508 O  O   . LEU A  1 563 ? -11.836 -24.311 -8.099  1.000 18.140 0 586  LEU A O   1 ? 
ATOM   4509 C  CB  . LEU A  1 563 ? -13.995 -22.664 -9.517  1.000 20.976 0 586  LEU A CB  1 ? 
ATOM   4510 C  CG  . LEU A  1 563 ? -14.440 -21.625 -10.545 1.000 20.488 0 586  LEU A CG  1 ? 
ATOM   4511 C  CD1 . LEU A  1 563 ? -15.486 -22.229 -11.465 1.000 23.764 0 586  LEU A CD1 1 ? 
ATOM   4512 C  CD2 . LEU A  1 563 ? -14.951 -20.360 -9.881  1.000 19.234 0 586  LEU A CD2 1 ? 
ATOM   4513 N  N   . LEU A  1 564 ? -13.106 -23.463 -6.436  1.000 18.576 0 587  LEU A N   1 ? 
ATOM   4514 C  CA  . LEU A  1 564 ? -12.896 -24.557 -5.508  1.000 20.864 0 587  LEU A CA  1 ? 
ATOM   4515 C  C   . LEU A  1 564 ? -14.242 -25.199 -5.183  1.000 19.491 0 587  LEU A C   1 ? 
ATOM   4516 O  O   . LEU A  1 564 ? -15.147 -24.521 -4.709  1.000 19.434 0 587  LEU A O   1 ? 
ATOM   4517 C  CB  . LEU A  1 564 ? -12.238 -23.964 -4.259  1.000 21.302 0 587  LEU A CB  1 ? 
ATOM   4518 C  CG  . LEU A  1 564 ? -11.973 -24.920 -3.109  1.000 21.194 0 587  LEU A CG  1 ? 
ATOM   4519 C  CD1 . LEU A  1 564 ? -11.017 -26.021 -3.541  1.000 24.468 0 587  LEU A CD1 1 ? 
ATOM   4520 C  CD2 . LEU A  1 564 ? -11.397 -24.129 -1.915  1.000 20.789 0 587  LEU A CD2 1 ? 
ATOM   4521 N  N   . ASP A  1 565 ? -14.311 -26.528 -5.322  1.000 18.940 0 588  ASP A N   1 ? 
ATOM   4522 C  CA  . ASP A  1 565 ? -15.541 -27.268 -5.136  1.000 19.664 0 588  ASP A CA  1 ? 
ATOM   4523 C  C   . ASP A  1 565 ? -15.533 -28.029 -3.807  1.000 19.241 0 588  ASP A C   1 ? 
ATOM   4524 O  O   . ASP A  1 565 ? -16.050 -27.542 -2.803  1.000 23.658 0 588  ASP A O   1 ? 
ATOM   4525 C  CB  . ASP A  1 565 ? -15.761 -28.154 -6.372  1.000 20.754 0 588  ASP A CB  1 ? 
ATOM   4526 C  CG  . ASP A  1 565 ? -16.951 -29.084 -6.281  1.000 21.069 0 588  ASP A CG  1 ? 
ATOM   4527 O  OD1 . ASP A  1 565 ? -17.841 -28.805 -5.476  1.000 20.522 0 588  ASP A OD1 1 ? 
ATOM   4528 O  OD2 . ASP A  1 565 ? -16.973 -30.117 -7.012  1.000 22.760 0 588  ASP A OD2 1 ? 
ATOM   4529 N  N   . THR A  1 566 ? -15.006 -29.254 -3.811  1.000 19.770 0 589  THR A N   1 ? 
ATOM   4530 C  CA  . THR A  1 566 ? -15.037 -30.133 -2.666  1.000 19.474 0 589  THR A CA  1 ? 
ATOM   4531 C  C   . THR A  1 566 ? -13.661 -30.186 -2.024  1.000 20.308 0 589  THR A C   1 ? 
ATOM   4532 O  O   . THR A  1 566 ? -12.653 -30.022 -2.712  1.000 19.686 0 589  THR A O   1 ? 
ATOM   4533 C  CB  . THR A  1 566 ? -15.458 -31.544 -3.068  1.000 22.061 0 589  THR A CB  1 ? 
ATOM   4534 O  OG1 . THR A  1 566 ? -14.718 -31.926 -4.234  1.000 23.731 0 589  THR A OG1 1 ? 
ATOM   4535 C  CG2 . THR A  1 566 ? -16.950 -31.655 -3.333  1.000 23.677 0 589  THR A CG2 1 ? 
ATOM   4536 N  N   . VAL A  1 567 ? -13.669 -30.534 -0.740  1.000 21.643 0 590  VAL A N   1 ? 
ATOM   4537 C  CA  . VAL A  1 567 ? -12.455 -30.930 -0.050  1.000 21.535 0 590  VAL A CA  1 ? 
ATOM   4538 C  C   . VAL A  1 567 ? -12.815 -32.120 0.832   1.000 21.818 0 590  VAL A C   1 ? 
ATOM   4539 O  O   . VAL A  1 567 ? -13.895 -32.166 1.450   1.000 19.979 0 590  VAL A O   1 ? 
ATOM   4540 C  CB  . VAL A  1 567 ? -11.829 -29.804 0.805   1.000 20.626 0 590  VAL A CB  1 ? 
ATOM   4541 C  CG1 . VAL A  1 567 ? -10.499 -30.276 1.369   1.000 20.594 0 590  VAL A CG1 1 ? 
ATOM   4542 C  CG2 . VAL A  1 567 ? -11.635 -28.500 0.056   1.000 19.994 0 590  VAL A CG2 1 ? 
ATOM   4543 N  N   . ASN A  1 568 ? -11.924 -33.111 0.905   1.000 21.057 0 591  ASN A N   1 ? 
ATOM   4544 C  CA  . ASN A  1 568 ? -12.130 -34.124 1.918   1.000 23.146 0 591  ASN A CA  1 ? 
ATOM   4545 C  C   . ASN A  1 568 ? -10.800 -34.568 2.523   1.000 20.744 0 591  ASN A C   1 ? 
ATOM   4546 O  O   . ASN A  1 568 ? -9.730  -34.395 1.941   1.000 24.567 0 591  ASN A O   1 ? 
ATOM   4547 C  CB  . ASN A  1 568 ? -12.935 -35.305 1.416   1.000 26.509 0 591  ASN A CB  1 ? 
ATOM   4548 C  CG  . ASN A  1 568 ? -12.270 -35.952 0.237   1.000 31.100 0 591  ASN A CG  1 ? 
ATOM   4549 O  OD1 . ASN A  1 568 ? -11.144 -36.427 0.328   1.000 33.022 0 591  ASN A OD1 1 ? 
ATOM   4550 N  ND2 . ASN A  1 568 ? -12.918 -35.855 -0.907  1.000 41.679 0 591  ASN A ND2 1 ? 
ATOM   4551 N  N   . ALA A  1 569 ? -10.905 -35.127 3.724   1.000 22.332 0 592  ALA A N   1 ? 
ATOM   4552 C  CA  . ALA A  1 569 ? -9.726  -35.491 4.491   1.000 21.766 0 592  ALA A CA  1 ? 
ATOM   4553 C  C   . ALA A  1 569 ? -9.983  -36.786 5.241   1.000 20.882 0 592  ALA A C   1 ? 
ATOM   4554 O  O   . ALA A  1 569 ? -11.065 -37.027 5.778   1.000 20.048 0 592  ALA A O   1 ? 
ATOM   4555 C  CB  . ALA A  1 569 ? -9.395  -34.381 5.455   1.000 25.131 0 592  ALA A CB  1 ? 
ATOM   4556 N  N   . ARG A  1 570 ? -8.883  -37.531 5.382   1.000 21.460 0 593  ARG A N   1 ? 
ATOM   4557 C  CA  . ARG A  1 570 ? -8.846  -38.709 6.205   1.000 23.824 0 593  ARG A CA  1 ? 
ATOM   4558 C  C   . ARG A  1 570 ? -7.455  -38.720 6.829   1.000 23.071 0 593  ARG A C   1 ? 
ATOM   4559 O  O   . ARG A  1 570 ? -6.470  -38.532 6.113   1.000 23.090 0 593  ARG A O   1 ? 
ATOM   4560 C  CB  . ARG A  1 570 ? -9.061  -39.977 5.359   1.000 30.258 0 593  ARG A CB  1 ? 
ATOM   4561 C  CG  . ARG A  1 570 ? -8.848  -41.271 6.141   1.000 40.077 0 593  ARG A CG  1 ? 
ATOM   4562 C  CD  . ARG A  1 570 ? -8.787  -42.497 5.242   1.000 52.456 0 593  ARG A CD  1 ? 
ATOM   4563 N  NE  . ARG A  1 570 ? -9.995  -42.625 4.446   1.000 59.563 0 593  ARG A NE  1 ? 
ATOM   4564 C  CZ  . ARG A  1 570 ? -11.196 -42.934 4.934   1.000 70.130 0 593  ARG A CZ  1 ? 
ATOM   4565 N  NH1 . ARG A  1 570 ? -11.327 -43.420 6.159   1.000 69.942 0 593  ARG A NH1 1 ? 
ATOM   4566 N  NH2 . ARG A  1 570 ? -12.268 -42.794 4.169   1.000 72.766 0 593  ARG A NH2 1 ? 
ATOM   4567 N  N   . VAL A  1 571 ? -7.397  -38.944 8.147   1.000 24.190 0 594  VAL A N   1 ? 
ATOM   4568 C  CA  . VAL A  1 571 ? -6.117  -39.029 8.822   1.000 23.241 0 594  VAL A CA  1 ? 
ATOM   4569 C  C   . VAL A  1 571 ? -6.033  -40.390 9.523   1.000 23.583 0 594  VAL A C   1 ? 
ATOM   4570 O  O   . VAL A  1 571 ? -7.045  -41.008 9.749   1.000 26.810 0 594  VAL A O   1 ? 
ATOM   4571 C  CB  . VAL A  1 571 ? -5.973  -37.848 9.809   1.000 24.004 0 594  VAL A CB  1 ? 
ATOM   4572 C  CG1 . VAL A  1 571 ? -5.817  -36.529 9.073   1.000 25.153 0 594  VAL A CG1 1 ? 
ATOM   4573 C  CG2 . VAL A  1 571 ? -7.137  -37.797 10.770  1.000 26.494 0 594  VAL A CG2 1 ? 
ATOM   4574 N  N   . LYS A  1 572 ? -4.830  -40.855 9.894   1.000 30.896 0 595  LYS A N   1 ? 
ATOM   4575 C  CA  . LYS A  1 572 ? -4.750  -42.141 10.589  1.000 38.441 0 595  LYS A CA  1 ? 
ATOM   4576 C  C   . LYS A  1 572 ? -4.130  -41.962 11.968  1.000 34.783 0 595  LYS A C   1 ? 
ATOM   4577 O  O   . LYS A  1 572 ? -3.395  -41.003 12.161  1.000 30.724 0 595  LYS A O   1 ? 
ATOM   4578 C  CB  . LYS A  1 572 ? -3.923  -43.156 9.800   1.000 53.518 0 595  LYS A CB  1 ? 
ATOM   4579 C  CG  . LYS A  1 572 ? -4.395  -44.597 9.981   1.000 64.895 0 595  LYS A CG  1 ? 
ATOM   4580 C  CD  . LYS A  1 572 ? -5.410  -45.044 8.941   1.000 74.516 0 595  LYS A CD  1 ? 
ATOM   4581 C  CE  . LYS A  1 572 ? -4.902  -44.937 7.515   1.000 76.321 0 595  LYS A CE  1 ? 
ATOM   4582 N  NZ  . LYS A  1 572 ? -3.509  -45.436 7.384   1.000 78.771 0 595  LYS A NZ  1 ? 
ATOM   4583 N  N   . LEU A  1 573 ? -4.460  -42.850 12.934  1.000 33.802 0 596  LEU A N   1 ? 
ATOM   4584 C  CA  . LEU A  1 573 ? -3.699  -42.919 14.192  1.000 39.145 0 596  LEU A CA  1 ? 
ATOM   4585 C  C   . LEU A  1 573 ? -2.394  -43.654 13.937  1.000 42.918 0 596  LEU A C   1 ? 
ATOM   4586 O  O   . LEU A  1 573 ? -2.437  -44.754 13.386  1.000 38.224 0 596  LEU A O   1 ? 
ATOM   4587 C  CB  . LEU A  1 573 ? -4.457  -43.693 15.278  1.000 55.133 0 596  LEU A CB  1 ? 
ATOM   4588 C  CG  . LEU A  1 573 ? -5.983  -43.585 15.284  1.000 62.734 0 596  LEU A CG  1 ? 
ATOM   4589 C  CD1 . LEU A  1 573 ? -6.624  -44.662 14.402  1.000 64.539 0 596  LEU A CD1 1 ? 
ATOM   4590 C  CD2 . LEU A  1 573 ? -6.520  -43.653 16.709  1.000 60.138 0 596  LEU A CD2 1 ? 
ATOM   4591 N  N   . GLU A  1 574 ? -1.266  -43.047 14.337  1.000 43.102 0 597  GLU A N   1 ? 
ATOM   4592 C  CA  . GLU A  1 574 ? 0.046   -43.680 14.341  1.000 44.206 0 597  GLU A CA  1 ? 
ATOM   4593 C  C   . GLU A  1 574 ? 0.337   -44.030 15.806  1.000 46.504 0 597  GLU A C   1 ? 
ATOM   4594 O  O   . GLU A  1 574 ? 0.867   -43.197 16.538  1.000 44.528 0 597  GLU A O   1 ? 
ATOM   4595 C  CB  . GLU A  1 574 ? 1.147   -42.773 13.757  1.000 41.365 0 597  GLU A CB  1 ? 
ATOM   4596 C  CG  . GLU A  1 574 ? 0.932   -42.344 12.313  1.000 47.616 0 597  GLU A CG  1 ? 
ATOM   4597 C  CD  . GLU A  1 574 ? 2.150   -41.794 11.567  1.000 54.424 0 597  GLU A CD  1 ? 
ATOM   4598 O  OE1 . GLU A  1 574 ? 2.399   -40.537 11.607  1.000 41.430 0 597  GLU A OE1 1 ? 
ATOM   4599 O  OE2 . GLU A  1 574 ? 2.841   -42.612 10.898  1.000 45.901 0 597  GLU A OE2 1 ? 
ATOM   4600 N  N   . HIS A  1 575 ? -0.096  -45.233 16.219  1.000 35.497 0 598  HIS A N   1 ? 
ATOM   4601 C  CA  . HIS A  1 575 ? -0.076  -45.737 17.590  1.000 28.086 0 598  HIS A CA  1 ? 
ATOM   4602 C  C   . HIS A  1 575 ? 1.332   -45.732 18.195  1.000 26.848 0 598  HIS A C   1 ? 
ATOM   4603 O  O   . HIS A  1 575 ? 2.313   -45.920 17.498  1.000 24.016 0 598  HIS A O   1 ? 
ATOM   4604 C  CB  . HIS A  1 575 ? -0.537  -47.201 17.543  1.000 26.284 0 598  HIS A CB  1 ? 
ATOM   4605 C  CG  . HIS A  1 575 ? -1.935  -47.390 17.071  1.000 27.915 0 598  HIS A CG  1 ? 
ATOM   4606 N  ND1 . HIS A  1 575 ? -3.038  -47.075 17.843  1.000 33.787 0 598  HIS A ND1 1 ? 
ATOM   4607 C  CD2 . HIS A  1 575 ? -2.415  -47.842 15.907  1.000 31.487 0 598  HIS A CD2 1 ? 
ATOM   4608 C  CE1 . HIS A  1 575 ? -4.150  -47.381 17.167  1.000 34.005 0 598  HIS A CE1 1 ? 
ATOM   4609 N  NE2 . HIS A  1 575 ? -3.789  -47.829 15.976  1.000 30.276 0 598  HIS A NE2 1 ? 
ATOM   4610 N  N   . HIS A  1 576 ? 1.415   -45.626 19.529  1.000 25.936 0 599  HIS A N   1 ? 
ATOM   4611 C  CA  . HIS A  1 576 ? 2.668   -45.759 20.248  1.000 24.713 0 599  HIS A CA  1 ? 
ATOM   4612 C  C   . HIS A  1 576 ? 3.219   -47.188 20.088  1.000 21.732 0 599  HIS A C   1 ? 
ATOM   4613 O  O   . HIS A  1 576 ? 2.471   -48.148 20.228  1.000 21.302 0 599  HIS A O   1 ? 
ATOM   4614 C  CB  . HIS A  1 576 ? 2.389   -45.473 21.723  1.000 25.668 0 599  HIS A CB  1 ? 
ATOM   4615 C  CG  . HIS A  1 576 ? 3.605   -45.547 22.561  1.000 24.007 0 599  HIS A CG  1 ? 
ATOM   4616 N  ND1 . HIS A  1 576 ? 4.662   -44.716 22.274  1.000 22.124 0 599  HIS A ND1 1 ? 
ATOM   4617 C  CD2 . HIS A  1 576 ? 3.981   -46.316 23.598  1.000 22.224 0 599  HIS A CD2 1 ? 
ATOM   4618 C  CE1 . HIS A  1 576 ? 5.643   -44.985 23.129  1.000 27.606 0 599  HIS A CE1 1 ? 
ATOM   4619 N  NE2 . HIS A  1 576 ? 5.261   -45.965 23.926  1.000 22.712 0 599  HIS A NE2 1 ? 
ATOM   4620 N  N   . HIS A  1 577 ? 4.529   -47.311 19.842  1.000 22.208 0 600  HIS A N   1 ? 
ATOM   4621 C  CA  . HIS A  1 577 ? 5.213   -48.604 19.872  1.000 21.426 0 600  HIS A CA  1 ? 
ATOM   4622 C  C   . HIS A  1 577 ? 6.690   -48.333 20.105  1.000 22.071 0 600  HIS A C   1 ? 
ATOM   4623 O  O   . HIS A  1 577 ? 7.125   -47.163 20.139  1.000 22.946 0 600  HIS A O   1 ? 
ATOM   4624 C  CB  . HIS A  1 577 ? 4.957   -49.413 18.587  1.000 19.451 0 600  HIS A CB  1 ? 
ATOM   4625 C  CG  . HIS A  1 577 ? 5.623   -48.763 17.403  1.000 21.240 0 600  HIS A CG  1 ? 
ATOM   4626 N  ND1 . HIS A  1 577 ? 6.947   -49.005 17.074  1.000 21.116 0 600  HIS A ND1 1 ? 
ATOM   4627 C  CD2 . HIS A  1 577 ? 5.141   -47.951 16.461  1.000 22.353 0 600  HIS A CD2 1 ? 
ATOM   4628 C  CE1 . HIS A  1 577 ? 7.252   -48.290 15.981  1.000 24.852 0 600  HIS A CE1 1 ? 
ATOM   4629 N  NE2 . HIS A  1 577 ? 6.147   -47.674 15.576  1.000 23.993 0 600  HIS A NE2 1 ? 
ATOM   4630 N  N   . HIS A  1 578 ? 7.443   -49.422 20.328  1.000 22.175 0 601  HIS A N   1 ? 
ATOM   4631 C  CA  . HIS A  1 578 ? 8.817   -49.360 20.785  1.000 23.280 0 601  HIS A CA  1 ? 
ATOM   4632 C  C   . HIS A  1 578 ? 9.820   -49.734 19.698  1.000 23.821 0 601  HIS A C   1 ? 
ATOM   4633 O  O   . HIS A  1 578 ? 11.003  -49.843 19.990  1.000 26.364 0 601  HIS A O   1 ? 
ATOM   4634 C  CB  . HIS A  1 578 ? 8.989   -50.256 22.028  1.000 23.941 0 601  HIS A CB  1 ? 
ATOM   4635 C  CG  . HIS A  1 578 ? 8.364   -49.675 23.264  1.000 23.894 0 601  HIS A CG  1 ? 
ATOM   4636 N  ND1 . HIS A  1 578 ? 8.560   -50.158 24.536  1.000 25.306 0 601  HIS A ND1 1 ? 
ATOM   4637 C  CD2 . HIS A  1 578 ? 7.528   -48.617 23.401  1.000 23.091 0 601  HIS A CD2 1 ? 
ATOM   4638 C  CE1 . HIS A  1 578 ? 7.893   -49.395 25.389  1.000 27.291 0 601  HIS A CE1 1 ? 
ATOM   4639 N  NE2 . HIS A  1 578 ? 7.242   -48.480 24.728  1.000 24.340 0 601  HIS A NE2 1 ? 
ATOM   4640 N  N   . HIS A  1 579 ? 9.387   -49.993 18.459  1.000 24.156 0 602  HIS A N   1 ? 
ATOM   4641 C  CA  . HIS A  1 579 ? 10.315  -50.321 17.388  1.000 23.839 0 602  HIS A CA  1 ? 
ATOM   4642 C  C   . HIS A  1 579 ? 10.839  -49.034 16.723  1.000 24.483 0 602  HIS A C   1 ? 
ATOM   4643 O  O   . HIS A  1 579 ? 10.434  -48.748 15.594  1.000 22.523 0 602  HIS A O   1 ? 
ATOM   4644 C  CB  . HIS A  1 579 ? 9.637   -51.266 16.391  1.000 24.447 0 602  HIS A CB  1 ? 
ATOM   4645 C  CG  . HIS A  1 579 ? 9.347   -52.612 16.972  1.000 22.542 0 602  HIS A CG  1 ? 
ATOM   4646 N  ND1 . HIS A  1 579 ? 10.254  -53.644 16.990  1.000 21.368 0 602  HIS A ND1 1 ? 
ATOM   4647 C  CD2 . HIS A  1 579 ? 8.223   -53.097 17.514  1.000 24.890 0 602  HIS A CD2 1 ? 
ATOM   4648 C  CE1 . HIS A  1 579 ? 9.696   -54.720 17.542  1.000 24.387 0 602  HIS A CE1 1 ? 
ATOM   4649 N  NE2 . HIS A  1 579 ? 8.454   -54.426 17.872  1.000 23.516 0 602  HIS A NE2 1 ? 
ATOM   4650 N  N   . HIS A  1 580 ? 11.689  -48.267 17.448  1.000 26.339 0 603  HIS A N   1 ? 
ATOM   4651 C  CA  . HIS A  1 580 ? 12.298  -47.007 16.994  1.000 27.201 0 603  HIS A CA  1 ? 
ATOM   4652 C  C   . HIS A  1 580 ? 13.841  -46.993 17.144  1.000 30.574 0 603  HIS A C   1 ? 
ATOM   4653 O  O   . HIS A  1 580 ? 14.267  -47.721 18.118  1.000 33.269 0 603  HIS A O   1 ? 
ATOM   4654 C  CB  . HIS A  1 580 ? 11.729  -45.818 17.800  1.000 28.313 0 603  HIS A CB  1 ? 
ATOM   4655 C  CG  . HIS A  1 580 ? 10.281  -45.546 17.513  1.000 28.799 0 603  HIS A CG  1 ? 
ATOM   4656 N  ND1 . HIS A  1 580 ? 9.765   -45.019 16.339  1.000 29.325 0 603  HIS A ND1 1 ? 
ATOM   4657 C  CD2 . HIS A  1 580 ? 9.221   -45.794 18.305  1.000 28.980 0 603  HIS A CD2 1 ? 
ATOM   4658 C  CE1 . HIS A  1 580 ? 8.428   -44.968 16.426  1.000 30.564 0 603  HIS A CE1 1 ? 
ATOM   4659 N  NE2 . HIS A  1 580 ? 8.069   -45.477 17.605  1.000 30.346 0 603  HIS A NE2 1 ? 
HETATM 4660 NI NI  . NI  B  2 .   ? -6.215  -2.793  24.244  1.000 22.719 0 701  NI  A NI  1 ? 
HETATM 4661 C  C1  . EDO C  3 .   ? -17.126 -25.425 12.285  1.000 37.502 0 702  EDO A C1  1 ? 
HETATM 4662 O  O1  . EDO C  3 .   ? -16.127 -25.954 11.436  1.000 25.105 0 702  EDO A O1  1 ? 
HETATM 4663 C  C2  . EDO C  3 .   ? -18.218 -26.399 12.600  1.000 43.675 0 702  EDO A C2  1 ? 
HETATM 4664 O  O2  . EDO C  3 .   ? -19.130 -26.503 11.555  1.000 46.930 0 702  EDO A O2  1 ? 
HETATM 4665 C  C1  . EDO D  3 .   ? -1.821  -10.097 17.279  1.000 23.241 0 703  EDO A C1  1 ? 
HETATM 4666 O  O1  . EDO D  3 .   ? -1.541  -8.706  17.292  1.000 26.400 0 703  EDO A O1  1 ? 
HETATM 4667 C  C2  . EDO D  3 .   ? -3.307  -10.255 17.274  1.000 23.805 0 703  EDO A C2  1 ? 
HETATM 4668 O  O2  . EDO D  3 .   ? -3.891  -9.888  16.033  1.000 21.705 0 703  EDO A O2  1 ? 
HETATM 4669 C  C1  . EDO E  3 .   ? -14.249 -23.362 49.978  1.000 30.378 0 704  EDO A C1  1 ? 
HETATM 4670 O  O1  . EDO E  3 .   ? -12.825 -23.642 50.025  1.000 28.001 0 704  EDO A O1  1 ? 
HETATM 4671 C  C2  . EDO E  3 .   ? -14.896 -23.375 51.309  1.000 32.276 0 704  EDO A C2  1 ? 
HETATM 4672 O  O2  . EDO E  3 .   ? -14.961 -24.657 51.996  1.000 33.282 0 704  EDO A O2  1 ? 
HETATM 4673 C  C1  . EDO F  3 .   ? -5.745  -15.228 -20.060 1.000 48.531 0 705  EDO A C1  1 ? 
HETATM 4674 O  O1  . EDO F  3 .   ? -5.142  -14.151 -19.406 1.000 42.204 0 705  EDO A O1  1 ? 
HETATM 4675 C  C2  . EDO F  3 .   ? -5.064  -16.455 -19.686 1.000 47.613 0 705  EDO A C2  1 ? 
HETATM 4676 O  O2  . EDO F  3 .   ? -5.909  -17.527 -19.501 1.000 49.516 0 705  EDO A O2  1 ? 
HETATM 4677 C  C1  . EDO G  3 .   ? -14.560 3.428   15.370  1.000 42.742 0 706  EDO A C1  1 ? 
HETATM 4678 O  O1  . EDO G  3 .   ? -13.169 3.754   15.293  1.000 46.380 0 706  EDO A O1  1 ? 
HETATM 4679 C  C2  . EDO G  3 .   ? -15.322 4.394   14.540  1.000 49.326 0 706  EDO A C2  1 ? 
HETATM 4680 O  O2  . EDO G  3 .   ? -14.803 4.452   13.218  1.000 41.101 0 706  EDO A O2  1 ? 
HETATM 4681 C  C1  . EDO H  3 .   ? -16.903 -22.058 54.592  1.000 46.337 0 707  EDO A C1  1 ? 
HETATM 4682 O  O1  . EDO H  3 .   ? -18.022 -22.890 54.765  1.000 42.578 0 707  EDO A O1  1 ? 
HETATM 4683 C  C2  . EDO H  3 .   ? -16.131 -21.860 55.842  1.000 50.590 0 707  EDO A C2  1 ? 
HETATM 4684 O  O2  . EDO H  3 .   ? -16.990 -21.828 56.972  1.000 54.265 0 707  EDO A O2  1 ? 
HETATM 4685 C  C1  . EDO I  3 .   ? 4.421   -34.016 43.263  1.000 51.301 0 708  EDO A C1  1 ? 
HETATM 4686 O  O1  . EDO I  3 .   ? 4.123   -35.113 44.137  1.000 53.172 0 708  EDO A O1  1 ? 
HETATM 4687 C  C2  . EDO I  3 .   ? 5.559   -34.244 42.335  1.000 53.849 0 708  EDO A C2  1 ? 
HETATM 4688 O  O2  . EDO I  3 .   ? 5.153   -34.470 40.982  1.000 60.533 0 708  EDO A O2  1 ? 
HETATM 4689 C  C1  . EDO J  3 .   ? -0.095  -35.701 17.445  1.000 43.499 0 709  EDO A C1  1 ? 
HETATM 4690 O  O1  . EDO J  3 .   ? 1.274   -35.842 17.065  1.000 51.109 0 709  EDO A O1  1 ? 
HETATM 4691 C  C2  . EDO J  3 .   ? -0.181  -34.955 18.718  1.000 40.414 0 709  EDO A C2  1 ? 
HETATM 4692 O  O2  . EDO J  3 .   ? -0.073  -35.848 19.813  1.000 37.388 0 709  EDO A O2  1 ? 
HETATM 4693 C  C1  . EDO K  3 .   ? -24.159 -24.571 58.296  1.000 53.135 0 710  EDO A C1  1 ? 
HETATM 4694 O  O1  . EDO K  3 .   ? -23.765 -23.659 59.289  1.000 54.656 0 710  EDO A O1  1 ? 
HETATM 4695 C  C2  . EDO K  3 .   ? -25.141 -23.930 57.388  1.000 52.958 0 710  EDO A C2  1 ? 
HETATM 4696 O  O2  . EDO K  3 .   ? -25.233 -24.642 56.182  1.000 52.924 0 710  EDO A O2  1 ? 
HETATM 4697 C  C1  . PEG L  4 .   ? 5.169   -34.022 32.726  1.000 63.345 0 711  PEG A C1  1 ? 
HETATM 4698 O  O1  . PEG L  4 .   ? 3.959   -33.597 33.340  1.000 54.985 0 711  PEG A O1  1 ? 
HETATM 4699 C  C2  . PEG L  4 .   ? 6.224   -32.953 32.729  1.000 63.878 0 711  PEG A C2  1 ? 
HETATM 4700 O  O2  . PEG L  4 .   ? 7.076   -33.120 33.862  1.000 57.916 0 711  PEG A O2  1 ? 
HETATM 4701 C  C3  . PEG L  4 .   ? 7.644   -31.910 34.344  1.000 54.127 0 711  PEG A C3  1 ? 
HETATM 4702 C  C4  . PEG L  4 .   ? 8.933   -31.631 33.651  1.000 60.259 0 711  PEG A C4  1 ? 
HETATM 4703 O  O4  . PEG L  4 .   ? 9.604   -30.539 34.248  1.000 60.382 0 711  PEG A O4  1 ? 
HETATM 4704 C  C1  . EDO M  3 .   ? -21.326 -32.001 41.784  1.000 57.151 0 712  EDO A C1  1 ? 
HETATM 4705 O  O1  . EDO M  3 .   ? -20.307 -31.417 40.990  1.000 47.141 0 712  EDO A O1  1 ? 
HETATM 4706 C  C2  . EDO M  3 .   ? -22.692 -31.882 41.205  1.000 53.539 0 712  EDO A C2  1 ? 
HETATM 4707 O  O2  . EDO M  3 .   ? -23.305 -33.118 40.810  1.000 56.983 0 712  EDO A O2  1 ? 
HETATM 4708 C  C1  . EDO N  3 .   ? -23.284 -20.960 1.468   1.000 51.659 0 713  EDO A C1  1 ? 
HETATM 4709 O  O1  . EDO N  3 .   ? -23.487 -19.530 1.566   1.000 48.984 0 713  EDO A O1  1 ? 
HETATM 4710 C  C2  . EDO N  3 .   ? -24.037 -21.804 2.411   1.000 51.974 0 713  EDO A C2  1 ? 
HETATM 4711 O  O2  . EDO N  3 .   ? -23.389 -22.079 3.654   1.000 42.044 0 713  EDO A O2  1 ? 
HETATM 4712 C  C1  . EDO O  3 .   ? 11.922  -15.098 28.419  1.000 54.767 0 714  EDO A C1  1 ? 
HETATM 4713 O  O1  . EDO O  3 .   ? 12.735  -13.962 28.576  1.000 64.887 0 714  EDO A O1  1 ? 
HETATM 4714 C  C2  . EDO O  3 .   ? 11.343  -15.547 29.690  1.000 55.958 0 714  EDO A C2  1 ? 
HETATM 4715 O  O2  . EDO O  3 .   ? 10.780  -16.821 29.548  1.000 56.385 0 714  EDO A O2  1 ? 
HETATM 4716 C  C1  . EDO P  3 .   ? -2.877  -42.212 4.837   1.000 48.535 0 715  EDO A C1  1 ? 
HETATM 4717 O  O1  . EDO P  3 .   ? -2.799  -43.360 5.662   1.000 52.783 0 715  EDO A O1  1 ? 
HETATM 4718 C  C2  . EDO P  3 .   ? -4.253  -41.734 4.666   1.000 45.219 0 715  EDO A C2  1 ? 
HETATM 4719 O  O2  . EDO P  3 .   ? -5.046  -41.915 5.814   1.000 44.118 0 715  EDO A O2  1 ? 
HETATM 4720 C  C1  . EDO Q  3 .   ? -12.068 -34.263 -11.414 1.000 47.931 0 716  EDO A C1  1 ? 
HETATM 4721 O  O1  . EDO Q  3 .   ? -12.968 -34.537 -10.366 1.000 51.548 0 716  EDO A O1  1 ? 
HETATM 4722 C  C2  . EDO Q  3 .   ? -12.628 -34.539 -12.757 1.000 51.018 0 716  EDO A C2  1 ? 
HETATM 4723 O  O2  . EDO Q  3 .   ? -14.051 -34.564 -12.777 1.000 49.493 0 716  EDO A O2  1 ? 
HETATM 4724 C  C1  . EDO R  3 .   ? -4.517  -33.650 -15.665 1.000 50.185 0 717  EDO A C1  1 ? 
HETATM 4725 O  O1  . EDO R  3 .   ? -4.779  -34.978 -15.259 1.000 53.541 0 717  EDO A O1  1 ? 
HETATM 4726 C  C2  . EDO R  3 .   ? -4.895  -33.400 -17.076 1.000 43.673 0 717  EDO A C2  1 ? 
HETATM 4727 O  O2  . EDO R  3 .   ? -4.953  -32.046 -17.445 1.000 39.442 0 717  EDO A O2  1 ? 
HETATM 4728 C  C1  . EDO S  3 .   ? -14.250 -38.765 3.653   1.000 60.027 0 718  EDO A C1  1 ? 
HETATM 4729 O  O1  . EDO S  3 .   ? -12.887 -38.315 3.787   1.000 51.691 0 718  EDO A O1  1 ? 
HETATM 4730 C  C2  . EDO S  3 .   ? -15.282 -37.767 4.033   1.000 57.423 0 718  EDO A C2  1 ? 
HETATM 4731 O  O2  . EDO S  3 .   ? -15.863 -37.887 5.342   1.000 57.402 0 718  EDO A O2  1 ? 
HETATM 4732 C  C1  . EDO T  3 .   ? -5.627  -35.144 39.627  1.000 48.745 0 719  EDO A C1  1 ? 
HETATM 4733 O  O1  . EDO T  3 .   ? -4.277  -35.525 39.892  1.000 49.082 0 719  EDO A O1  1 ? 
HETATM 4734 C  C2  . EDO T  3 .   ? -6.161  -35.731 38.392  1.000 52.112 0 719  EDO A C2  1 ? 
HETATM 4735 O  O2  . EDO T  3 .   ? -6.084  -37.148 38.361  1.000 55.615 0 719  EDO A O2  1 ? 
HETATM 4736 C  C1  . EDO U  3 .   ? -20.281 -35.576 34.820  1.000 59.003 0 720  EDO A C1  1 ? 
HETATM 4737 O  O1  . EDO U  3 .   ? -20.618 -36.646 33.961  1.000 61.524 0 720  EDO A O1  1 ? 
HETATM 4738 C  C2  . EDO U  3 .   ? -21.416 -35.040 35.637  1.000 60.762 0 720  EDO A C2  1 ? 
HETATM 4739 O  O2  . EDO U  3 .   ? -22.633 -35.720 35.462  1.000 63.280 0 720  EDO A O2  1 ? 
HETATM 4740 CL CL  . CL  V  5 .   ? -16.192 -9.410  45.177  1.000 21.223 0 721  CL  A CL  1 ? 
HETATM 4741 CL CL  . CL  W  5 .   ? -16.487 -0.866  7.777   1.000 50.186 0 722  CL  A CL  1 ? 
HETATM 4742 CL CL  . CL  X  5 .   ? 19.385  -11.957 14.193  1.000 50.073 0 723  CL  A CL  1 ? 
HETATM 4743 CL CL  . CL  Y  5 .   ? -1.758  -14.587 47.895  1.000 56.556 0 724  CL  A CL  1 ? 
HETATM 4744 CL CL  . CL  Z  5 .   ? 1.901   -31.806 28.439  1.000 70.044 0 725  CL  A CL  1 ? 
HETATM 4745 CL CL  . CL  AA 5 .   ? -20.970 -15.022 6.557   1.000 63.982 0 726  CL  A CL  1 ? 
HETATM 4746 CL CL  . CL  BA 5 .   ? -11.907 -3.872  44.589  1.000 50.652 0 727  CL  A CL  1 ? 
HETATM 4747 CL CL  . CL  CA 5 .   ? -11.450 -3.696  26.054  1.000 70.698 0 728  CL  A CL  1 ? 
HETATM 4748 O  O   . HOH DA 6 .   ? -2.721  -4.824  -7.583  1.000 43.988 0 801  HOH A O   1 ? 
HETATM 4749 O  O   . HOH DA 6 .   ? -35.393 -22.582 35.161  1.000 44.672 0 802  HOH A O   1 ? 
HETATM 4750 O  O   . HOH DA 6 .   ? 7.672   -19.298 21.095  1.000 30.040 0 803  HOH A O   1 ? 
HETATM 4751 O  O   . HOH DA 6 .   ? -27.483 -23.444 -6.251  1.000 33.021 0 804  HOH A O   1 ? 
HETATM 4752 O  O   . HOH DA 6 .   ? -10.676 -9.958  61.285  1.000 35.556 0 805  HOH A O   1 ? 
HETATM 4753 O  O   . HOH DA 6 .   ? -5.321  -0.296  19.370  1.000 45.750 0 806  HOH A O   1 ? 
HETATM 4754 O  O   . HOH DA 6 .   ? -23.616 -39.165 13.955  1.000 54.088 0 807  HOH A O   1 ? 
HETATM 4755 O  O   . HOH DA 6 .   ? -3.049  -34.794 43.918  1.000 38.531 0 808  HOH A O   1 ? 
HETATM 4756 O  O   . HOH DA 6 .   ? -12.002 -8.358  27.486  1.000 39.552 0 809  HOH A O   1 ? 
HETATM 4757 O  O   . HOH DA 6 .   ? -20.582 -28.781 12.607  1.000 42.847 0 810  HOH A O   1 ? 
HETATM 4758 O  O   . HOH DA 6 .   ? 1.617   -45.172 7.066   1.000 59.436 0 811  HOH A O   1 ? 
HETATM 4759 O  O   . HOH DA 6 .   ? 3.873   -39.214 10.254  1.000 44.084 0 812  HOH A O   1 ? 
HETATM 4760 O  O   . HOH DA 6 .   ? 3.379   -34.865 16.435  1.000 50.371 0 813  HOH A O   1 ? 
HETATM 4761 O  O   . HOH DA 6 .   ? -25.936 -17.930 3.479   1.000 54.091 0 814  HOH A O   1 ? 
HETATM 4762 O  O   . HOH DA 6 .   ? -12.457 -40.592 3.143   1.000 55.071 0 815  HOH A O   1 ? 
HETATM 4763 O  O   . HOH DA 6 .   ? -6.146  -33.252 43.559  1.000 37.942 0 816  HOH A O   1 ? 
HETATM 4764 O  O   . HOH DA 6 .   ? -31.602 -28.319 40.933  1.000 42.571 0 817  HOH A O   1 ? 
HETATM 4765 O  O   . HOH DA 6 .   ? -11.179 -3.745  51.586  1.000 44.220 0 818  HOH A O   1 ? 
HETATM 4766 O  O   . HOH DA 6 .   ? -3.235  0.618   13.208  1.000 45.709 0 819  HOH A O   1 ? 
HETATM 4767 O  O   . HOH DA 6 .   ? -17.714 -33.598 11.269  1.000 36.331 0 820  HOH A O   1 ? 
HETATM 4768 O  O   . HOH DA 6 .   ? -30.876 -19.290 43.374  1.000 41.814 0 821  HOH A O   1 ? 
HETATM 4769 O  O   . HOH DA 6 .   ? -7.795  -27.106 35.199  1.000 29.328 0 822  HOH A O   1 ? 
HETATM 4770 O  O   . HOH DA 6 .   ? 9.390   -31.187 -4.701  1.000 53.007 0 823  HOH A O   1 ? 
HETATM 4771 O  O   . HOH DA 6 .   ? -1.451  -35.369 45.923  1.000 39.680 0 824  HOH A O   1 ? 
HETATM 4772 O  O   . HOH DA 6 .   ? -22.332 -29.228 -11.262 1.000 46.115 0 825  HOH A O   1 ? 
HETATM 4773 O  O   . HOH DA 6 .   ? -17.364 -0.958  -0.380  1.000 48.662 0 826  HOH A O   1 ? 
HETATM 4774 O  O   . HOH DA 6 .   ? 8.508   -30.460 28.095  1.000 40.015 0 827  HOH A O   1 ? 
HETATM 4775 O  O   . HOH DA 6 .   ? -8.228  -37.711 -7.027  1.000 52.337 0 828  HOH A O   1 ? 
HETATM 4776 O  O   . HOH DA 6 .   ? -1.795  -39.077 12.287  1.000 38.387 0 829  HOH A O   1 ? 
HETATM 4777 O  O   . HOH DA 6 .   ? -29.887 -26.471 20.388  1.000 48.587 0 830  HOH A O   1 ? 
HETATM 4778 O  O   . HOH DA 6 .   ? 9.099   -27.358 47.090  1.000 33.260 0 831  HOH A O   1 ? 
HETATM 4779 O  O   . HOH DA 6 .   ? -3.035  -36.513 -14.306 1.000 51.627 0 832  HOH A O   1 ? 
HETATM 4780 O  O   . HOH DA 6 .   ? -2.074  -28.151 51.509  1.000 36.223 0 833  HOH A O   1 ? 
HETATM 4781 O  O   . HOH DA 6 .   ? -27.882 -32.417 28.561  1.000 36.992 0 834  HOH A O   1 ? 
HETATM 4782 O  O   . HOH DA 6 .   ? -21.310 -29.925 -18.454 1.000 39.488 0 835  HOH A O   1 ? 
HETATM 4783 O  O   . HOH DA 6 .   ? 12.576  -20.209 29.188  1.000 35.068 0 836  HOH A O   1 ? 
HETATM 4784 O  O   . HOH DA 6 .   ? -17.768 1.052   11.340  1.000 33.297 0 837  HOH A O   1 ? 
HETATM 4785 O  O   . HOH DA 6 .   ? -34.495 -32.033 34.313  1.000 48.515 0 838  HOH A O   1 ? 
HETATM 4786 O  O   . HOH DA 6 .   ? -26.667 -9.883  47.722  1.000 43.874 0 839  HOH A O   1 ? 
HETATM 4787 O  O   . HOH DA 6 .   ? -3.282  -47.017 12.604  1.000 30.835 0 840  HOH A O   1 ? 
HETATM 4788 O  O   . HOH DA 6 .   ? -17.190 -14.698 32.875  1.000 18.053 0 841  HOH A O   1 ? 
HETATM 4789 O  O   . HOH DA 6 .   ? 7.353   -14.702 6.051   1.000 30.268 0 842  HOH A O   1 ? 
HETATM 4790 O  O   . HOH DA 6 .   ? 11.759  -13.795 9.153   1.000 27.287 0 843  HOH A O   1 ? 
HETATM 4791 O  O   . HOH DA 6 .   ? -4.158  -0.885  8.924   1.000 28.563 0 844  HOH A O   1 ? 
HETATM 4792 O  O   . HOH DA 6 .   ? 10.323  -23.934 10.723  1.000 39.103 0 845  HOH A O   1 ? 
HETATM 4793 O  O   . HOH DA 6 .   ? -18.736 -30.332 -11.427 1.000 27.873 0 846  HOH A O   1 ? 
HETATM 4794 O  O   . HOH DA 6 .   ? -9.064  -39.960 25.190  1.000 37.622 0 847  HOH A O   1 ? 
HETATM 4795 O  O   . HOH DA 6 .   ? -21.720 -12.933 40.647  1.000 20.641 0 848  HOH A O   1 ? 
HETATM 4796 O  O   . HOH DA 6 .   ? 8.342   -20.459 34.615  1.000 29.745 0 849  HOH A O   1 ? 
HETATM 4797 O  O   . HOH DA 6 .   ? 5.681   -35.626 35.656  1.000 45.101 0 850  HOH A O   1 ? 
HETATM 4798 O  O   . HOH DA 6 .   ? -9.896  4.260   11.517  1.000 35.059 0 851  HOH A O   1 ? 
HETATM 4799 O  O   . HOH DA 6 .   ? -8.994  -27.524 50.813  1.000 37.820 0 852  HOH A O   1 ? 
HETATM 4800 O  O   . HOH DA 6 .   ? -24.138 -12.639 38.873  1.000 21.695 0 853  HOH A O   1 ? 
HETATM 4801 O  O   . HOH DA 6 .   ? 1.730   -43.218 30.558  1.000 34.473 0 854  HOH A O   1 ? 
HETATM 4802 O  O   . HOH DA 6 .   ? -11.671 -14.338 -4.189  1.000 24.622 0 855  HOH A O   1 ? 
HETATM 4803 O  O   . HOH DA 6 .   ? -6.681  -30.960 40.626  1.000 25.957 0 856  HOH A O   1 ? 
HETATM 4804 O  O   . HOH DA 6 .   ? -30.358 -10.802 42.851  1.000 32.253 0 857  HOH A O   1 ? 
HETATM 4805 O  O   . HOH DA 6 .   ? -5.491  -19.654 22.092  1.000 22.506 0 858  HOH A O   1 ? 
HETATM 4806 O  O   . HOH DA 6 .   ? -14.666 -6.122  26.281  1.000 44.282 0 859  HOH A O   1 ? 
HETATM 4807 O  O   . HOH DA 6 .   ? -0.790  -40.589 15.017  1.000 37.211 0 860  HOH A O   1 ? 
HETATM 4808 O  O   . HOH DA 6 .   ? 7.671   -22.377 3.282   1.000 36.570 0 861  HOH A O   1 ? 
HETATM 4809 O  O   . HOH DA 6 .   ? -9.019  -26.085 -15.042 1.000 27.967 0 862  HOH A O   1 ? 
HETATM 4810 O  O   . HOH DA 6 .   ? 0.507   -3.957  -2.409  1.000 36.928 0 863  HOH A O   1 ? 
HETATM 4811 O  O   . HOH DA 6 .   ? 1.862   -6.719  -10.343 1.000 45.034 0 864  HOH A O   1 ? 
HETATM 4812 O  O   . HOH DA 6 .   ? 11.503  -34.143 4.976   1.000 40.338 0 865  HOH A O   1 ? 
HETATM 4813 O  O   . HOH DA 6 .   ? -20.208 -17.311 4.419   1.000 29.578 0 866  HOH A O   1 ? 
HETATM 4814 O  O   . HOH DA 6 .   ? -15.477 -0.038  51.790  1.000 35.914 0 867  HOH A O   1 ? 
HETATM 4815 O  O   . HOH DA 6 .   ? -9.565  -10.139 25.728  1.000 37.221 0 868  HOH A O   1 ? 
HETATM 4816 O  O   . HOH DA 6 .   ? -11.731 -7.389  17.153  1.000 26.380 0 869  HOH A O   1 ? 
HETATM 4817 O  O   . HOH DA 6 .   ? -25.071 -8.567  57.039  1.000 43.908 0 870  HOH A O   1 ? 
HETATM 4818 O  O   . HOH DA 6 .   ? -13.900 -6.911  -2.306  1.000 33.718 0 871  HOH A O   1 ? 
HETATM 4819 O  O   . HOH DA 6 .   ? 2.685   -36.905 30.776  1.000 37.397 0 872  HOH A O   1 ? 
HETATM 4820 O  O   . HOH DA 6 .   ? -2.928  -5.173  9.771   1.000 19.760 0 873  HOH A O   1 ? 
HETATM 4821 O  O   . HOH DA 6 .   ? -10.096 -13.686 12.489  1.000 19.250 0 874  HOH A O   1 ? 
HETATM 4822 O  O   . HOH DA 6 .   ? -19.935 -33.017 -4.959  1.000 35.734 0 875  HOH A O   1 ? 
HETATM 4823 O  O   . HOH DA 6 .   ? 10.281  -6.638  21.567  1.000 28.144 0 876  HOH A O   1 ? 
HETATM 4824 O  O   . HOH DA 6 .   ? 8.968   -12.442 14.855  1.000 26.905 0 877  HOH A O   1 ? 
HETATM 4825 O  O   . HOH DA 6 .   ? 6.635   -25.478 -2.453  1.000 35.052 0 878  HOH A O   1 ? 
HETATM 4826 O  O   . HOH DA 6 .   ? -1.915  -27.824 15.853  1.000 19.172 0 879  HOH A O   1 ? 
HETATM 4827 O  O   . HOH DA 6 .   ? -23.672 -3.980  19.872  1.000 49.721 0 880  HOH A O   1 ? 
HETATM 4828 O  O   . HOH DA 6 .   ? -23.156 -13.693 55.767  1.000 40.677 0 881  HOH A O   1 ? 
HETATM 4829 O  O   . HOH DA 6 .   ? -15.347 -25.928 34.902  1.000 31.474 0 882  HOH A O   1 ? 
HETATM 4830 O  O   . HOH DA 6 .   ? 7.642   -1.249  7.312   1.000 29.321 0 883  HOH A O   1 ? 
HETATM 4831 O  O   . HOH DA 6 .   ? -0.554  -8.037  7.869   1.000 21.863 0 884  HOH A O   1 ? 
HETATM 4832 O  O   . HOH DA 6 .   ? 0.826   -10.599 14.740  1.000 19.057 0 885  HOH A O   1 ? 
HETATM 4833 O  O   . HOH DA 6 .   ? -4.599  -15.376 -8.534  1.000 22.924 0 886  HOH A O   1 ? 
HETATM 4834 O  O   . HOH DA 6 .   ? -19.898 -28.485 41.098  1.000 32.671 0 887  HOH A O   1 ? 
HETATM 4835 O  O   . HOH DA 6 .   ? -22.323 -4.774  24.384  1.000 42.947 0 888  HOH A O   1 ? 
HETATM 4836 O  O   . HOH DA 6 .   ? -13.518 -25.683 9.044   1.000 17.136 0 889  HOH A O   1 ? 
HETATM 4837 O  O   . HOH DA 6 .   ? -15.761 -28.179 13.039  1.000 26.065 0 890  HOH A O   1 ? 
HETATM 4838 O  O   . HOH DA 6 .   ? -13.526 -23.724 35.298  1.000 28.217 0 891  HOH A O   1 ? 
HETATM 4839 O  O   . HOH DA 6 .   ? -17.447 -9.277  37.939  1.000 20.568 0 892  HOH A O   1 ? 
HETATM 4840 O  O   . HOH DA 6 .   ? -19.273 -8.626  61.776  1.000 29.980 0 893  HOH A O   1 ? 
HETATM 4841 O  O   . HOH DA 6 .   ? -2.727  -29.605 13.831  1.000 21.425 0 894  HOH A O   1 ? 
HETATM 4842 O  O   . HOH DA 6 .   ? 6.932   -14.464 45.099  1.000 34.428 0 895  HOH A O   1 ? 
HETATM 4843 O  O   . HOH DA 6 .   ? 9.007   -11.141 35.447  1.000 48.880 0 896  HOH A O   1 ? 
HETATM 4844 O  O   . HOH DA 6 .   ? 9.471   -17.929 34.708  1.000 26.371 0 897  HOH A O   1 ? 
HETATM 4845 O  O   . HOH DA 6 .   ? -19.406 -19.632 -13.096 1.000 28.512 0 898  HOH A O   1 ? 
HETATM 4846 O  O   . HOH DA 6 .   ? -15.722 -34.062 -5.423  1.000 35.663 0 899  HOH A O   1 ? 
HETATM 4847 O  O   . HOH DA 6 .   ? 7.533   -1.028  16.116  1.000 38.308 0 900  HOH A O   1 ? 
HETATM 4848 O  O   . HOH DA 6 .   ? 2.879   1.122   1.472   1.000 44.159 0 901  HOH A O   1 ? 
HETATM 4849 O  O   . HOH DA 6 .   ? 5.212   -13.238 25.469  1.000 18.913 0 902  HOH A O   1 ? 
HETATM 4850 O  O   . HOH DA 6 .   ? -6.559  -14.045 54.685  1.000 27.616 0 903  HOH A O   1 ? 
HETATM 4851 O  O   . HOH DA 6 .   ? -13.292 -20.029 35.884  1.000 36.072 0 904  HOH A O   1 ? 
HETATM 4852 O  O   . HOH DA 6 .   ? -14.346 -26.403 -21.071 1.000 45.265 0 905  HOH A O   1 ? 
HETATM 4853 O  O   . HOH DA 6 .   ? -1.965  -7.205  37.340  1.000 46.570 0 906  HOH A O   1 ? 
HETATM 4854 O  O   . HOH DA 6 .   ? -20.353 -26.667 55.068  1.000 42.407 0 907  HOH A O   1 ? 
HETATM 4855 O  O   . HOH DA 6 .   ? -11.943 -1.766  9.270   1.000 17.601 0 908  HOH A O   1 ? 
HETATM 4856 O  O   . HOH DA 6 .   ? -1.350  -10.488 -0.332  1.000 37.923 0 909  HOH A O   1 ? 
HETATM 4857 O  O   . HOH DA 6 .   ? -5.619  -7.693  51.542  1.000 23.517 0 910  HOH A O   1 ? 
HETATM 4858 O  O   . HOH DA 6 .   ? -13.451 -27.918 41.882  1.000 28.138 0 911  HOH A O   1 ? 
HETATM 4859 O  O   . HOH DA 6 .   ? -6.624  2.086   -1.143  1.000 58.073 0 912  HOH A O   1 ? 
HETATM 4860 O  O   . HOH DA 6 .   ? 5.419   -20.339 14.021  1.000 21.414 0 913  HOH A O   1 ? 
HETATM 4861 O  O   . HOH DA 6 .   ? -12.820 -13.114 21.380  1.000 20.190 0 914  HOH A O   1 ? 
HETATM 4862 O  O   . HOH DA 6 .   ? -0.757  -14.970 -1.886  1.000 20.665 0 915  HOH A O   1 ? 
HETATM 4863 O  O   . HOH DA 6 .   ? 7.064   -15.338 12.590  1.000 24.155 0 916  HOH A O   1 ? 
HETATM 4864 O  O   . HOH DA 6 .   ? 3.793   -34.983 8.889   1.000 37.425 0 917  HOH A O   1 ? 
HETATM 4865 O  O   . HOH DA 6 .   ? -7.509  -24.627 36.132  1.000 36.782 0 918  HOH A O   1 ? 
HETATM 4866 O  O   . HOH DA 6 .   ? -18.398 -2.565  40.874  1.000 40.189 0 919  HOH A O   1 ? 
HETATM 4867 O  O   . HOH DA 6 .   ? -8.408  -43.257 9.334   1.000 39.127 0 920  HOH A O   1 ? 
HETATM 4868 O  O   . HOH DA 6 .   ? 12.353  -12.029 22.407  1.000 39.795 0 921  HOH A O   1 ? 
HETATM 4869 O  O   . HOH DA 6 .   ? -10.586 -9.685  -9.797  1.000 26.737 0 922  HOH A O   1 ? 
HETATM 4870 O  O   . HOH DA 6 .   ? -1.601  -21.044 1.226   1.000 18.550 0 923  HOH A O   1 ? 
HETATM 4871 O  O   . HOH DA 6 .   ? -3.146  -15.089 9.467   1.000 17.432 0 924  HOH A O   1 ? 
HETATM 4872 O  O   . HOH DA 6 .   ? -5.453  -40.034 -3.938  1.000 49.804 0 925  HOH A O   1 ? 
HETATM 4873 O  O   . HOH DA 6 .   ? -23.410 -3.815  49.658  1.000 25.147 0 926  HOH A O   1 ? 
HETATM 4874 O  O   . HOH DA 6 .   ? -26.588 -18.136 44.284  1.000 28.511 0 927  HOH A O   1 ? 
HETATM 4875 O  O   . HOH DA 6 .   ? -10.725 -25.261 38.985  1.000 26.309 0 928  HOH A O   1 ? 
HETATM 4876 O  O   . HOH DA 6 .   ? 5.609   -44.857 18.432  1.000 29.686 0 929  HOH A O   1 ? 
HETATM 4877 O  O   . HOH DA 6 .   ? -9.429  -31.777 -19.578 1.000 42.438 0 930  HOH A O   1 ? 
HETATM 4878 O  O   . HOH DA 6 .   ? -16.509 -31.147 33.978  1.000 29.556 0 931  HOH A O   1 ? 
HETATM 4879 O  O   . HOH DA 6 .   ? 4.878   -19.961 -4.631  1.000 40.289 0 932  HOH A O   1 ? 
HETATM 4880 O  O   . HOH DA 6 .   ? -6.967  -25.371 50.898  1.000 30.183 0 933  HOH A O   1 ? 
HETATM 4881 O  O   . HOH DA 6 .   ? -7.047  -8.159  42.032  1.000 17.626 0 934  HOH A O   1 ? 
HETATM 4882 O  O   . HOH DA 6 .   ? 5.139   -42.885 20.378  1.000 30.607 0 935  HOH A O   1 ? 
HETATM 4883 O  O   . HOH DA 6 .   ? -10.515 -33.590 -15.580 1.000 56.368 0 936  HOH A O   1 ? 
HETATM 4884 O  O   . HOH DA 6 .   ? -10.815 -7.451  14.312  1.000 20.231 0 937  HOH A O   1 ? 
HETATM 4885 O  O   . HOH DA 6 .   ? -2.610  -18.830 24.287  1.000 19.596 0 938  HOH A O   1 ? 
HETATM 4886 O  O   . HOH DA 6 .   ? 6.069   -14.354 2.085   1.000 38.200 0 939  HOH A O   1 ? 
HETATM 4887 O  O   . HOH DA 6 .   ? -9.632  -36.968 15.772  1.000 29.084 0 940  HOH A O   1 ? 
HETATM 4888 O  O   . HOH DA 6 .   ? -24.683 -14.536 52.789  1.000 25.831 0 941  HOH A O   1 ? 
HETATM 4889 O  O   . HOH DA 6 .   ? 4.451   -27.146 48.303  1.000 33.733 0 942  HOH A O   1 ? 
HETATM 4890 O  O   . HOH DA 6 .   ? -14.378 5.452   53.553  1.000 46.926 0 943  HOH A O   1 ? 
HETATM 4891 O  O   . HOH DA 6 .   ? -13.714 -10.858 28.361  1.000 23.265 0 944  HOH A O   1 ? 
HETATM 4892 O  O   . HOH DA 6 .   ? 2.184   1.939   17.629  1.000 33.992 0 945  HOH A O   1 ? 
HETATM 4893 O  O   . HOH DA 6 .   ? -7.108  -18.411 60.198  1.000 39.743 0 946  HOH A O   1 ? 
HETATM 4894 O  O   . HOH DA 6 .   ? -7.621  -35.234 50.849  1.000 32.848 0 947  HOH A O   1 ? 
HETATM 4895 O  O   . HOH DA 6 .   ? 4.190   -12.108 -7.650  1.000 42.624 0 948  HOH A O   1 ? 
HETATM 4896 O  O   . HOH DA 6 .   ? -25.173 -18.832 17.084  1.000 55.420 0 949  HOH A O   1 ? 
HETATM 4897 O  O   . HOH DA 6 .   ? -17.082 -25.141 36.700  1.000 21.079 0 950  HOH A O   1 ? 
HETATM 4898 O  O   . HOH DA 6 .   ? 3.614   -38.901 42.062  1.000 25.917 0 951  HOH A O   1 ? 
HETATM 4899 O  O   . HOH DA 6 .   ? -16.437 -8.155  25.792  1.000 24.385 0 952  HOH A O   1 ? 
HETATM 4900 O  O   . HOH DA 6 .   ? 0.998   -1.419  28.590  1.000 28.330 0 953  HOH A O   1 ? 
HETATM 4901 O  O   . HOH DA 6 .   ? -14.579 -0.971  -2.668  1.000 41.293 0 954  HOH A O   1 ? 
HETATM 4902 O  O   . HOH DA 6 .   ? 1.401   -13.015 12.912  1.000 19.869 0 955  HOH A O   1 ? 
HETATM 4903 O  O   . HOH DA 6 .   ? -11.931 -11.176 51.079  1.000 21.166 0 956  HOH A O   1 ? 
HETATM 4904 O  O   . HOH DA 6 .   ? -3.030  -16.206 16.967  1.000 39.609 0 957  HOH A O   1 ? 
HETATM 4905 O  O   . HOH DA 6 .   ? -24.486 -31.149 44.181  1.000 35.208 0 958  HOH A O   1 ? 
HETATM 4906 O  O   . HOH DA 6 .   ? 0.577   -19.364 -8.014  1.000 36.306 0 959  HOH A O   1 ? 
HETATM 4907 O  O   . HOH DA 6 .   ? -23.482 -6.999  41.555  1.000 27.226 0 960  HOH A O   1 ? 
HETATM 4908 O  O   . HOH DA 6 .   ? 6.863   1.813   11.238  1.000 38.123 0 961  HOH A O   1 ? 
HETATM 4909 O  O   . HOH DA 6 .   ? -23.068 -23.750 5.746   1.000 31.551 0 962  HOH A O   1 ? 
HETATM 4910 O  O   . HOH DA 6 .   ? -1.271  -38.155 -3.531  1.000 33.816 0 963  HOH A O   1 ? 
HETATM 4911 O  O   . HOH DA 6 .   ? -27.758 -16.976 60.513  1.000 38.543 0 964  HOH A O   1 ? 
HETATM 4912 O  O   . HOH DA 6 .   ? 2.417   -36.592 20.545  1.000 39.150 0 965  HOH A O   1 ? 
HETATM 4913 O  O   . HOH DA 6 .   ? -14.172 -7.420  58.363  1.000 30.863 0 966  HOH A O   1 ? 
HETATM 4914 O  O   . HOH DA 6 .   ? 0.853   -17.908 -12.956 1.000 25.730 0 967  HOH A O   1 ? 
HETATM 4915 O  O   . HOH DA 6 .   ? -23.119 -26.737 6.171   1.000 41.248 0 968  HOH A O   1 ? 
HETATM 4916 O  O   . HOH DA 6 .   ? -10.096 4.992   8.936   1.000 30.638 0 969  HOH A O   1 ? 
HETATM 4917 O  O   . HOH DA 6 .   ? 6.675   -26.458 -5.046  1.000 32.867 0 970  HOH A O   1 ? 
HETATM 4918 O  O   . HOH DA 6 .   ? -31.901 -21.908 40.135  1.000 33.559 0 971  HOH A O   1 ? 
HETATM 4919 O  O   . HOH DA 6 .   ? -13.933 -22.494 -15.944 1.000 31.993 0 972  HOH A O   1 ? 
HETATM 4920 O  O   . HOH DA 6 .   ? 9.914   -12.218 29.646  1.000 29.097 0 973  HOH A O   1 ? 
HETATM 4921 O  O   . HOH DA 6 .   ? 5.619   -39.589 36.666  1.000 33.272 0 974  HOH A O   1 ? 
HETATM 4922 O  O   . HOH DA 6 .   ? -0.518  -4.585  13.281  1.000 21.546 0 975  HOH A O   1 ? 
HETATM 4923 O  O   . HOH DA 6 .   ? -32.077 -24.774 42.646  1.000 45.107 0 976  HOH A O   1 ? 
HETATM 4924 O  O   . HOH DA 6 .   ? 3.281   -24.795 19.255  1.000 23.128 0 977  HOH A O   1 ? 
HETATM 4925 O  O   . HOH DA 6 .   ? -14.737 -14.127 -5.610  1.000 29.914 0 978  HOH A O   1 ? 
HETATM 4926 O  O   . HOH DA 6 .   ? -19.872 -31.046 5.262   1.000 31.214 0 979  HOH A O   1 ? 
HETATM 4927 O  O   . HOH DA 6 .   ? -10.091 -11.117 -15.063 1.000 34.659 0 980  HOH A O   1 ? 
HETATM 4928 O  O   . HOH DA 6 .   ? -5.089  -9.950  30.860  1.000 24.095 0 981  HOH A O   1 ? 
HETATM 4929 O  O   . HOH DA 6 .   ? -8.572  0.688   3.461   1.000 28.100 0 982  HOH A O   1 ? 
HETATM 4930 O  O   . HOH DA 6 .   ? -10.448 -18.217 34.277  1.000 19.566 0 983  HOH A O   1 ? 
HETATM 4931 O  O   . HOH DA 6 .   ? -9.439  -37.975 1.766   1.000 30.148 0 984  HOH A O   1 ? 
HETATM 4932 O  O   . HOH DA 6 .   ? -2.659  -8.924  13.309  1.000 21.071 0 985  HOH A O   1 ? 
HETATM 4933 O  O   . HOH DA 6 .   ? -4.345  -14.510 35.428  1.000 20.909 0 986  HOH A O   1 ? 
HETATM 4934 O  O   . HOH DA 6 .   ? -1.798  -5.919  16.826  1.000 21.757 0 987  HOH A O   1 ? 
HETATM 4935 O  O   . HOH DA 6 .   ? -17.366 -33.173 -0.233  1.000 26.149 0 988  HOH A O   1 ? 
HETATM 4936 O  O   . HOH DA 6 .   ? -14.764 -16.157 7.099   1.000 17.031 0 989  HOH A O   1 ? 
HETATM 4937 O  O   . HOH DA 6 .   ? 6.360   -0.313  13.606  1.000 38.395 0 990  HOH A O   1 ? 
HETATM 4938 O  O   . HOH DA 6 .   ? -4.608  -16.922 18.702  1.000 29.283 0 991  HOH A O   1 ? 
HETATM 4939 O  O   . HOH DA 6 .   ? -4.281  -18.669 28.273  1.000 19.744 0 992  HOH A O   1 ? 
HETATM 4940 O  O   . HOH DA 6 .   ? -9.145  -18.337 23.554  1.000 16.458 0 993  HOH A O   1 ? 
HETATM 4941 O  O   . HOH DA 6 .   ? -6.590  -22.604 37.124  1.000 25.016 0 994  HOH A O   1 ? 
HETATM 4942 O  O   . HOH DA 6 .   ? -24.753 -2.005  53.857  1.000 25.566 0 995  HOH A O   1 ? 
HETATM 4943 O  O   . HOH DA 6 .   ? -16.946 -16.397 -12.366 1.000 34.475 0 996  HOH A O   1 ? 
HETATM 4944 O  O   . HOH DA 6 .   ? 0.161   -33.558 -16.426 1.000 38.296 0 997  HOH A O   1 ? 
HETATM 4945 O  O   . HOH DA 6 .   ? 5.669   -14.474 14.613  1.000 26.318 0 998  HOH A O   1 ? 
HETATM 4946 O  O   . HOH DA 6 .   ? -3.312  -8.953  51.260  1.000 43.283 0 999  HOH A O   1 ? 
HETATM 4947 O  O   . HOH DA 6 .   ? -21.227 -31.171 1.943   1.000 39.343 0 1000 HOH A O   1 ? 
HETATM 4948 O  O   . HOH DA 6 .   ? -21.913 -10.086 32.818  1.000 24.887 0 1001 HOH A O   1 ? 
HETATM 4949 O  O   . HOH DA 6 .   ? -11.718 -11.337 44.231  1.000 18.750 0 1002 HOH A O   1 ? 
HETATM 4950 O  O   . HOH DA 6 .   ? -6.653  1.136   21.365  1.000 39.752 0 1003 HOH A O   1 ? 
HETATM 4951 O  O   . HOH DA 6 .   ? -12.177 -22.280 8.936   1.000 20.709 0 1004 HOH A O   1 ? 
HETATM 4952 O  O   . HOH DA 6 .   ? -0.142  -48.140 21.056  1.000 22.120 0 1005 HOH A O   1 ? 
HETATM 4953 O  O   . HOH DA 6 .   ? -15.703 -8.649  -0.921  1.000 33.215 0 1006 HOH A O   1 ? 
HETATM 4954 O  O   . HOH DA 6 .   ? -1.122  -7.957  -1.082  1.000 51.057 0 1007 HOH A O   1 ? 
HETATM 4955 O  O   . HOH DA 6 .   ? -3.264  -45.255 19.884  1.000 42.209 0 1008 HOH A O   1 ? 
HETATM 4956 O  O   . HOH DA 6 .   ? -21.583 -35.263 11.766  1.000 59.588 0 1009 HOH A O   1 ? 
HETATM 4957 O  O   . HOH DA 6 .   ? -6.214  -16.672 11.850  1.000 18.136 0 1010 HOH A O   1 ? 
HETATM 4958 O  O   . HOH DA 6 .   ? -15.924 -2.675  37.746  1.000 38.314 0 1011 HOH A O   1 ? 
HETATM 4959 O  O   . HOH DA 6 .   ? -16.366 -20.548 37.411  1.000 25.510 0 1012 HOH A O   1 ? 
HETATM 4960 O  O   . HOH DA 6 .   ? -24.786 -33.533 14.223  1.000 40.239 0 1013 HOH A O   1 ? 
HETATM 4961 O  O   . HOH DA 6 .   ? -23.108 -20.881 15.103  1.000 47.334 0 1014 HOH A O   1 ? 
HETATM 4962 O  O   . HOH DA 6 .   ? 2.187   -28.456 25.275  1.000 25.475 0 1015 HOH A O   1 ? 
HETATM 4963 O  O   . HOH DA 6 .   ? -30.886 -18.111 49.650  1.000 44.170 0 1016 HOH A O   1 ? 
HETATM 4964 O  O   . HOH DA 6 .   ? -23.350 -26.284 -4.002  1.000 22.326 0 1017 HOH A O   1 ? 
HETATM 4965 O  O   . HOH DA 6 .   ? -18.628 1.887   18.288  1.000 42.667 0 1018 HOH A O   1 ? 
HETATM 4966 O  O   . HOH DA 6 .   ? -22.965 -6.482  33.288  1.000 29.195 0 1019 HOH A O   1 ? 
HETATM 4967 O  O   . HOH DA 6 .   ? 1.515   -44.899 10.116  1.000 51.202 0 1020 HOH A O   1 ? 
HETATM 4968 O  O   . HOH DA 6 .   ? 10.641  -47.010 13.463  1.000 29.995 0 1021 HOH A O   1 ? 
HETATM 4969 O  O   . HOH DA 6 .   ? 3.240   -6.894  7.811   1.000 30.529 0 1022 HOH A O   1 ? 
HETATM 4970 O  O   . HOH DA 6 .   ? 3.108   -30.592 41.968  1.000 23.092 0 1023 HOH A O   1 ? 
HETATM 4971 O  O   . HOH DA 6 .   ? -12.142 -10.256 17.226  1.000 25.056 0 1024 HOH A O   1 ? 
HETATM 4972 O  O   . HOH DA 6 .   ? -33.729 -23.243 32.974  1.000 29.559 0 1025 HOH A O   1 ? 
HETATM 4973 O  O   . HOH DA 6 .   ? -20.401 -19.558 11.281  1.000 33.090 0 1026 HOH A O   1 ? 
HETATM 4974 O  O   . HOH DA 6 .   ? -20.247 -25.066 15.394  1.000 36.782 0 1027 HOH A O   1 ? 
HETATM 4975 O  O   . HOH DA 6 .   ? -8.110  -18.147 -17.496 1.000 35.026 0 1028 HOH A O   1 ? 
HETATM 4976 O  O   . HOH DA 6 .   ? 1.540   -24.433 9.800   1.000 24.160 0 1029 HOH A O   1 ? 
HETATM 4977 O  O   . HOH DA 6 .   ? -26.635 -32.726 23.349  1.000 41.727 0 1030 HOH A O   1 ? 
HETATM 4978 O  O   . HOH DA 6 .   ? -9.778  -19.967 27.428  1.000 23.373 0 1031 HOH A O   1 ? 
HETATM 4979 O  O   . HOH DA 6 .   ? -25.027 -22.347 -2.163  1.000 37.200 0 1032 HOH A O   1 ? 
HETATM 4980 O  O   . HOH DA 6 .   ? 2.961   -3.009  20.456  1.000 23.962 0 1033 HOH A O   1 ? 
HETATM 4981 O  O   . HOH DA 6 .   ? 0.769   -16.891 -0.623  1.000 21.667 0 1034 HOH A O   1 ? 
HETATM 4982 O  O   . HOH DA 6 .   ? -0.303  -17.347 23.475  1.000 19.408 0 1035 HOH A O   1 ? 
HETATM 4983 O  O   . HOH DA 6 .   ? -1.475  -26.480 -19.241 1.000 45.258 0 1036 HOH A O   1 ? 
HETATM 4984 O  O   . HOH DA 6 .   ? 8.993   -26.627 24.369  1.000 33.671 0 1037 HOH A O   1 ? 
HETATM 4985 O  O   . HOH DA 6 .   ? -6.573  -17.365 -8.000  1.000 22.201 0 1038 HOH A O   1 ? 
HETATM 4986 O  O   . HOH DA 6 .   ? 1.368   -15.191 9.256   1.000 25.411 0 1039 HOH A O   1 ? 
HETATM 4987 O  O   . HOH DA 6 .   ? -13.771 -30.049 12.359  1.000 22.078 0 1040 HOH A O   1 ? 
HETATM 4988 O  O   . HOH DA 6 .   ? -3.778  -36.428 16.341  1.000 26.478 0 1041 HOH A O   1 ? 
HETATM 4989 O  O   . HOH DA 6 .   ? 0.913   -4.620  17.884  1.000 20.543 0 1042 HOH A O   1 ? 
HETATM 4990 O  O   . HOH DA 6 .   ? -25.035 -36.965 33.438  1.000 41.519 0 1043 HOH A O   1 ? 
HETATM 4991 O  O   . HOH DA 6 .   ? -17.874 -3.693  -0.216  1.000 49.620 0 1044 HOH A O   1 ? 
HETATM 4992 O  O   . HOH DA 6 .   ? -8.507  -22.581 34.065  1.000 30.554 0 1045 HOH A O   1 ? 
HETATM 4993 O  O   . HOH DA 6 .   ? -12.256 -2.998  19.325  1.000 28.647 0 1046 HOH A O   1 ? 
HETATM 4994 O  O   . HOH DA 6 .   ? 3.844   -15.788 -15.898 1.000 43.853 0 1047 HOH A O   1 ? 
HETATM 4995 O  O   . HOH DA 6 .   ? -9.519  -14.905 7.266   1.000 16.315 0 1048 HOH A O   1 ? 
HETATM 4996 O  O   . HOH DA 6 .   ? -20.150 -13.128 8.794   1.000 25.431 0 1049 HOH A O   1 ? 
HETATM 4997 O  O   . HOH DA 6 .   ? -23.071 -31.921 20.309  1.000 31.229 0 1050 HOH A O   1 ? 
HETATM 4998 O  O   . HOH DA 6 .   ? -7.004  -36.086 15.568  1.000 27.816 0 1051 HOH A O   1 ? 
HETATM 4999 O  O   . HOH DA 6 .   ? 4.818   -23.285 11.513  1.000 21.195 0 1052 HOH A O   1 ? 
HETATM 5000 O  O   . HOH DA 6 .   ? -24.715 -4.369  58.097  1.000 23.279 0 1053 HOH A O   1 ? 
HETATM 5001 O  O   . HOH DA 6 .   ? 4.358   2.821   5.297   1.000 34.644 0 1054 HOH A O   1 ? 
HETATM 5002 O  O   . HOH DA 6 .   ? 6.717   -17.172 18.281  1.000 23.820 0 1055 HOH A O   1 ? 
HETATM 5003 O  O   . HOH DA 6 .   ? 4.625   -25.508 12.919  1.000 23.055 0 1056 HOH A O   1 ? 
HETATM 5004 O  O   . HOH DA 6 .   ? 0.571   -42.636 -10.658 1.000 54.516 0 1057 HOH A O   1 ? 
HETATM 5005 O  O   . HOH DA 6 .   ? -2.174  -26.063 18.220  1.000 21.719 0 1058 HOH A O   1 ? 
HETATM 5006 O  O   . HOH DA 6 .   ? -30.081 -15.695 50.528  1.000 34.087 0 1059 HOH A O   1 ? 
HETATM 5007 O  O   . HOH DA 6 .   ? -0.364  -15.581 15.715  1.000 22.426 0 1060 HOH A O   1 ? 
HETATM 5008 O  O   . HOH DA 6 .   ? -0.548  -9.140  1.540   1.000 35.715 0 1061 HOH A O   1 ? 
HETATM 5009 O  O   . HOH DA 6 .   ? -6.632  -27.028 14.280  1.000 17.131 0 1062 HOH A O   1 ? 
HETATM 5010 O  O   . HOH DA 6 .   ? 4.949   -19.072 -13.969 1.000 44.801 0 1063 HOH A O   1 ? 
HETATM 5011 O  O   . HOH DA 6 .   ? 2.584   -5.419  28.915  1.000 29.272 0 1064 HOH A O   1 ? 
HETATM 5012 O  O   . HOH DA 6 .   ? -0.814  -19.759 53.246  1.000 33.689 0 1065 HOH A O   1 ? 
HETATM 5013 O  O   . HOH DA 6 .   ? -19.065 -14.847 -0.027  1.000 20.968 0 1066 HOH A O   1 ? 
HETATM 5014 O  O   . HOH DA 6 .   ? -12.412 -17.790 11.269  1.000 19.171 0 1067 HOH A O   1 ? 
HETATM 5015 O  O   . HOH DA 6 .   ? -21.640 -27.211 14.549  1.000 48.192 0 1068 HOH A O   1 ? 
HETATM 5016 O  O   . HOH DA 6 .   ? -20.347 -22.942 -18.848 1.000 46.220 0 1069 HOH A O   1 ? 
HETATM 5017 O  O   . HOH DA 6 .   ? -1.311  -11.090 3.136   1.000 26.394 0 1070 HOH A O   1 ? 
HETATM 5018 O  O   . HOH DA 6 .   ? -10.727 -9.335  29.356  1.000 35.427 0 1071 HOH A O   1 ? 
HETATM 5019 O  O   . HOH DA 6 .   ? -15.652 -24.398 38.820  1.000 20.321 0 1072 HOH A O   1 ? 
HETATM 5020 O  O   . HOH DA 6 .   ? -27.087 -38.264 29.308  1.000 45.523 0 1073 HOH A O   1 ? 
HETATM 5021 O  O   . HOH DA 6 .   ? -4.685  -39.651 23.559  1.000 32.573 0 1074 HOH A O   1 ? 
HETATM 5022 O  O   . HOH DA 6 .   ? -10.571 -22.000 -17.825 1.000 33.618 0 1075 HOH A O   1 ? 
HETATM 5023 O  O   . HOH DA 6 .   ? 13.533  -47.693 20.828  1.000 45.734 0 1076 HOH A O   1 ? 
HETATM 5024 O  O   . HOH DA 6 .   ? -32.942 -22.425 26.295  1.000 35.223 0 1077 HOH A O   1 ? 
HETATM 5025 O  O   . HOH DA 6 .   ? 6.212   -14.802 37.199  1.000 27.150 0 1078 HOH A O   1 ? 
HETATM 5026 O  O   . HOH DA 6 .   ? -11.528 -26.934 33.247  1.000 31.460 0 1079 HOH A O   1 ? 
HETATM 5027 O  O   . HOH DA 6 .   ? -8.663  -7.720  45.151  1.000 20.889 0 1080 HOH A O   1 ? 
HETATM 5028 O  O   . HOH DA 6 .   ? -14.456 -14.532 32.218  1.000 19.002 0 1081 HOH A O   1 ? 
HETATM 5029 O  O   . HOH DA 6 .   ? -16.843 -35.619 12.087  1.000 47.344 0 1082 HOH A O   1 ? 
HETATM 5030 O  O   . HOH DA 6 .   ? -12.833 -24.741 53.844  1.000 48.530 0 1083 HOH A O   1 ? 
HETATM 5031 O  O   . HOH DA 6 .   ? -11.690 -20.725 32.148  1.000 18.603 0 1084 HOH A O   1 ? 
HETATM 5032 O  O   . HOH DA 6 .   ? 2.429   -17.551 -2.887  1.000 25.281 0 1085 HOH A O   1 ? 
HETATM 5033 O  O   . HOH DA 6 .   ? 8.932   -13.298 12.215  1.000 24.846 0 1086 HOH A O   1 ? 
HETATM 5034 O  O   . HOH DA 6 .   ? -5.548  -24.814 25.891  1.000 18.665 0 1087 HOH A O   1 ? 
HETATM 5035 O  O   . HOH DA 6 .   ? -7.184  -20.642 35.324  1.000 20.634 0 1088 HOH A O   1 ? 
HETATM 5036 O  O   . HOH DA 6 .   ? -19.637 -31.788 35.357  1.000 24.520 0 1089 HOH A O   1 ? 
HETATM 5037 O  O   . HOH DA 6 .   ? -18.874 -29.257 54.408  1.000 46.842 0 1090 HOH A O   1 ? 
HETATM 5038 O  O   . HOH DA 6 .   ? -10.513 -17.630 13.598  1.000 17.616 0 1091 HOH A O   1 ? 
HETATM 5039 O  O   . HOH DA 6 .   ? -17.808 -34.654 6.990   1.000 28.990 0 1092 HOH A O   1 ? 
HETATM 5040 O  O   . HOH DA 6 .   ? -9.745  -10.927 46.414  1.000 20.215 0 1093 HOH A O   1 ? 
HETATM 5041 O  O   . HOH DA 6 .   ? -27.298 -13.988 27.852  1.000 32.043 0 1094 HOH A O   1 ? 
HETATM 5042 O  O   . HOH DA 6 .   ? 0.313   -5.588  -6.571  1.000 40.945 0 1095 HOH A O   1 ? 
HETATM 5043 O  O   . HOH DA 6 .   ? -12.871 -39.065 22.410  1.000 48.096 0 1096 HOH A O   1 ? 
HETATM 5044 O  O   . HOH DA 6 .   ? -4.282  -10.543 0.726   1.000 26.791 0 1097 HOH A O   1 ? 
HETATM 5045 O  O   . HOH DA 6 .   ? -33.184 -27.357 39.047  1.000 52.245 0 1098 HOH A O   1 ? 
HETATM 5046 O  O   . HOH DA 6 .   ? -27.235 -23.771 48.117  1.000 33.494 0 1099 HOH A O   1 ? 
HETATM 5047 O  O   . HOH DA 6 .   ? 16.880  -48.840 18.239  1.000 23.918 0 1100 HOH A O   1 ? 
HETATM 5048 O  O   . HOH DA 6 .   ? -21.444 -7.293  25.284  1.000 26.271 0 1101 HOH A O   1 ? 
HETATM 5049 O  O   . HOH DA 6 .   ? -33.795 -25.865 31.937  1.000 29.547 0 1102 HOH A O   1 ? 
HETATM 5050 O  O   . HOH DA 6 .   ? -7.879  -2.316  -6.110  1.000 36.708 0 1103 HOH A O   1 ? 
HETATM 5051 O  O   . HOH DA 6 .   ? -13.259 -4.014  40.199  1.000 36.100 0 1104 HOH A O   1 ? 
HETATM 5052 O  O   . HOH DA 6 .   ? -3.721  -5.733  41.730  1.000 36.283 0 1105 HOH A O   1 ? 
HETATM 5053 O  O   . HOH DA 6 .   ? -8.181  -41.774 35.973  1.000 42.592 0 1106 HOH A O   1 ? 
HETATM 5054 O  O   . HOH DA 6 .   ? -0.507  -6.899  19.284  1.000 22.534 0 1107 HOH A O   1 ? 
HETATM 5055 O  O   . HOH DA 6 .   ? -19.582 -32.319 18.726  1.000 24.007 0 1108 HOH A O   1 ? 
HETATM 5056 O  O   . HOH DA 6 .   ? -0.184  -19.412 15.731  1.000 18.788 0 1109 HOH A O   1 ? 
HETATM 5057 O  O   . HOH DA 6 .   ? -12.425 -33.466 -3.499  1.000 30.207 0 1110 HOH A O   1 ? 
HETATM 5058 O  O   . HOH DA 6 .   ? 7.969   -5.941  23.204  1.000 23.328 0 1111 HOH A O   1 ? 
HETATM 5059 O  O   . HOH DA 6 .   ? -17.538 -19.337 31.438  1.000 19.746 0 1112 HOH A O   1 ? 
HETATM 5060 O  O   . HOH DA 6 .   ? 5.790   2.152   27.086  1.000 39.665 0 1113 HOH A O   1 ? 
HETATM 5061 O  O   . HOH DA 6 .   ? 8.486   -27.506 41.416  1.000 20.808 0 1114 HOH A O   1 ? 
HETATM 5062 O  O   . HOH DA 6 .   ? 6.271   -32.117 46.394  1.000 42.488 0 1115 HOH A O   1 ? 
HETATM 5063 O  O   . HOH DA 6 .   ? -26.767 -17.295 48.620  1.000 38.862 0 1116 HOH A O   1 ? 
HETATM 5064 O  O   . HOH DA 6 .   ? 0.695   -1.854  18.375  1.000 25.657 0 1117 HOH A O   1 ? 
HETATM 5065 O  O   . HOH DA 6 .   ? 11.652  -44.872 14.186  1.000 50.559 0 1118 HOH A O   1 ? 
HETATM 5066 O  O   . HOH DA 6 .   ? -16.038 -13.478 -7.951  1.000 32.519 0 1119 HOH A O   1 ? 
HETATM 5067 O  O   . HOH DA 6 .   ? 8.400   -45.002 21.533  1.000 48.413 0 1120 HOH A O   1 ? 
HETATM 5068 O  O   . HOH DA 6 .   ? 6.222   -28.197 1.139   1.000 25.602 0 1121 HOH A O   1 ? 
HETATM 5069 O  O   . HOH DA 6 .   ? -6.922  -32.987 37.002  1.000 27.433 0 1122 HOH A O   1 ? 
HETATM 5070 O  O   . HOH DA 6 .   ? -2.398  -16.292 35.229  1.000 20.598 0 1123 HOH A O   1 ? 
HETATM 5071 O  O   . HOH DA 6 .   ? -4.711  -6.313  46.801  1.000 49.774 0 1124 HOH A O   1 ? 
HETATM 5072 O  O   . HOH DA 6 .   ? 11.147  -7.406  29.486  1.000 55.097 0 1125 HOH A O   1 ? 
HETATM 5073 O  O   . HOH DA 6 .   ? 8.418   -16.812 37.148  1.000 25.504 0 1126 HOH A O   1 ? 
HETATM 5074 O  O   . HOH DA 6 .   ? -6.980  -33.488 -18.884 1.000 45.090 0 1127 HOH A O   1 ? 
HETATM 5075 O  O   . HOH DA 6 .   ? -13.190 -25.090 32.500  1.000 23.717 0 1128 HOH A O   1 ? 
HETATM 5076 O  O   . HOH DA 6 .   ? -15.516 -12.586 44.869  1.000 20.137 0 1129 HOH A O   1 ? 
HETATM 5077 O  O   . HOH DA 6 .   ? -21.628 -27.712 8.859   1.000 44.947 0 1130 HOH A O   1 ? 
HETATM 5078 O  O   . HOH DA 6 .   ? 6.406   -3.243  26.342  1.000 34.066 0 1131 HOH A O   1 ? 
HETATM 5079 O  O   . HOH DA 6 .   ? -18.600 -12.538 61.093  1.000 34.708 0 1132 HOH A O   1 ? 
HETATM 5080 O  O   . HOH DA 6 .   ? -0.169  -11.254 -4.529  1.000 43.680 0 1133 HOH A O   1 ? 
HETATM 5081 O  O   . HOH DA 6 .   ? -20.510 -9.979  4.762   1.000 26.085 0 1134 HOH A O   1 ? 
HETATM 5082 O  O   . HOH DA 6 .   ? 0.080   -11.280 5.290   1.000 31.613 0 1135 HOH A O   1 ? 
HETATM 5083 O  O   . HOH DA 6 .   ? 10.950  0.641   22.478  1.000 43.842 0 1136 HOH A O   1 ? 
HETATM 5084 O  O   . HOH DA 6 .   ? -28.526 -23.629 -9.791  1.000 33.741 0 1137 HOH A O   1 ? 
HETATM 5085 O  O   . HOH DA 6 .   ? -5.615  4.304   4.311   1.000 39.277 0 1138 HOH A O   1 ? 
HETATM 5086 O  O   . HOH DA 6 .   ? -11.122 -14.998 38.371  1.000 17.925 0 1139 HOH A O   1 ? 
HETATM 5087 O  O   . HOH DA 6 .   ? -25.823 -11.827 27.038  1.000 27.942 0 1140 HOH A O   1 ? 
HETATM 5088 O  O   . HOH DA 6 .   ? 0.268   -9.566  -15.015 1.000 40.947 0 1141 HOH A O   1 ? 
HETATM 5089 O  O   . HOH DA 6 .   ? -5.080  -22.167 7.670   1.000 19.239 0 1142 HOH A O   1 ? 
HETATM 5090 O  O   . HOH DA 6 .   ? -5.121  -38.727 13.818  1.000 28.958 0 1143 HOH A O   1 ? 
HETATM 5091 O  O   A HOH DA 6 .   ? -0.639  -5.741  35.121  0.500 11.021 0 1144 HOH A O   1 ? 
HETATM 5092 O  O   B HOH DA 6 .   ? -1.812  -5.779  35.017  0.500 22.910 0 1144 HOH A O   1 ? 
HETATM 5093 O  O   . HOH DA 6 .   ? 7.966   2.184   25.793  1.000 30.488 0 1145 HOH A O   1 ? 
HETATM 5094 O  O   . HOH DA 6 .   ? -5.009  -38.351 29.989  1.000 27.965 0 1146 HOH A O   1 ? 
HETATM 5095 O  O   . HOH DA 6 .   ? 13.460  -25.919 34.884  1.000 29.750 0 1147 HOH A O   1 ? 
HETATM 5096 O  O   . HOH DA 6 .   ? 2.465   -35.998 34.013  1.000 38.989 0 1148 HOH A O   1 ? 
HETATM 5097 O  O   . HOH DA 6 .   ? 9.761   -6.506  7.970   1.000 53.190 0 1149 HOH A O   1 ? 
HETATM 5098 O  O   . HOH DA 6 .   ? -4.084  3.599   1.462   1.000 38.301 0 1150 HOH A O   1 ? 
HETATM 5099 O  O   . HOH DA 6 .   ? 0.397   -18.941 1.442   1.000 19.796 0 1151 HOH A O   1 ? 
HETATM 5100 O  O   . HOH DA 6 .   ? -2.761  -21.209 53.909  1.000 24.417 0 1152 HOH A O   1 ? 
HETATM 5101 O  O   . HOH DA 6 .   ? 16.938  -31.563 0.749   1.000 34.934 0 1153 HOH A O   1 ? 
HETATM 5102 O  O   . HOH DA 6 .   ? 11.897  -18.056 38.159  1.000 44.938 0 1154 HOH A O   1 ? 
HETATM 5103 O  O   . HOH DA 6 .   ? -25.228 -24.960 45.753  1.000 31.216 0 1155 HOH A O   1 ? 
HETATM 5104 O  O   . HOH DA 6 .   ? 3.393   -23.134 -18.545 1.000 47.602 0 1156 HOH A O   1 ? 
HETATM 5105 O  O   . HOH DA 6 .   ? 7.879   -17.532 13.738  1.000 33.194 0 1157 HOH A O   1 ? 
HETATM 5106 O  O   . HOH DA 6 .   ? 6.944   -3.104  1.766   1.000 49.421 0 1158 HOH A O   1 ? 
HETATM 5107 O  O   . HOH DA 6 .   ? -32.816 -29.547 37.718  1.000 57.443 0 1159 HOH A O   1 ? 
HETATM 5108 O  O   . HOH DA 6 .   ? -25.789 -9.862  30.806  1.000 47.304 0 1160 HOH A O   1 ? 
HETATM 5109 O  O   . HOH DA 6 .   ? -15.727 -26.537 40.582  1.000 26.295 0 1161 HOH A O   1 ? 
HETATM 5110 O  O   . HOH DA 6 .   ? -1.835  -6.621  11.724  1.000 22.760 0 1162 HOH A O   1 ? 
HETATM 5111 O  O   . HOH DA 6 .   ? -34.042 -15.633 30.211  1.000 33.216 0 1163 HOH A O   1 ? 
HETATM 5112 O  O   . HOH DA 6 .   ? -13.911 -41.445 12.043  1.000 40.448 0 1164 HOH A O   1 ? 
HETATM 5113 O  O   . HOH DA 6 .   ? -6.624  -30.318 37.851  1.000 22.240 0 1165 HOH A O   1 ? 
HETATM 5114 O  O   . HOH DA 6 .   ? -5.735  -3.427  -8.304  1.000 45.845 0 1166 HOH A O   1 ? 
HETATM 5115 O  O   . HOH DA 6 .   ? -10.355 -11.380 15.564  1.000 24.352 0 1167 HOH A O   1 ? 
HETATM 5116 O  O   . HOH DA 6 .   ? 6.735   -45.991 13.226  1.000 49.498 0 1168 HOH A O   1 ? 
HETATM 5117 O  O   . HOH DA 6 .   ? 11.777  -6.180  17.595  1.000 30.327 0 1169 HOH A O   1 ? 
HETATM 5118 O  O   . HOH DA 6 .   ? -26.008 -5.149  19.047  1.000 53.532 0 1170 HOH A O   1 ? 
HETATM 5119 O  O   . HOH DA 6 .   ? -1.463  -12.803 49.736  1.000 34.349 0 1171 HOH A O   1 ? 
HETATM 5120 O  O   . HOH DA 6 .   ? -22.807 -17.409 -10.964 1.000 31.996 0 1172 HOH A O   1 ? 
HETATM 5121 O  O   . HOH DA 6 .   ? 6.268   -8.000  22.727  1.000 20.363 0 1173 HOH A O   1 ? 
HETATM 5122 O  O   . HOH DA 6 .   ? -19.341 -22.438 12.690  1.000 31.196 0 1174 HOH A O   1 ? 
HETATM 5123 O  O   . HOH DA 6 .   ? 2.933   -13.648 10.683  1.000 21.132 0 1175 HOH A O   1 ? 
HETATM 5124 O  O   . HOH DA 6 .   ? -12.874 -7.636  -7.398  1.000 28.573 0 1176 HOH A O   1 ? 
HETATM 5125 O  O   . HOH DA 6 .   ? 9.658   -29.885 -2.090  1.000 44.222 0 1177 HOH A O   1 ? 
HETATM 5126 O  O   . HOH DA 6 .   ? -13.263 -11.761 -11.868 1.000 39.369 0 1178 HOH A O   1 ? 
HETATM 5127 O  O   . HOH DA 6 .   ? -35.712 -14.485 38.872  1.000 34.624 0 1179 HOH A O   1 ? 
HETATM 5128 O  O   . HOH DA 6 .   ? -6.357  2.965   10.857  1.000 34.355 0 1180 HOH A O   1 ? 
HETATM 5129 O  O   . HOH DA 6 .   ? 10.760  -26.410 10.913  1.000 39.563 0 1181 HOH A O   1 ? 
HETATM 5130 O  O   . HOH DA 6 .   ? 12.019  -10.898 26.116  1.000 27.316 0 1182 HOH A O   1 ? 
HETATM 5131 O  O   . HOH DA 6 .   ? -10.684 -27.460 41.360  1.000 21.700 0 1183 HOH A O   1 ? 
HETATM 5132 O  O   . HOH DA 6 .   ? -17.638 -17.827 5.352   1.000 22.130 0 1184 HOH A O   1 ? 
HETATM 5133 O  O   . HOH DA 6 .   ? -14.663 -30.833 -16.087 1.000 28.569 0 1185 HOH A O   1 ? 
HETATM 5134 O  O   . HOH DA 6 .   ? -8.087  -31.831 44.023  1.000 36.500 0 1186 HOH A O   1 ? 
HETATM 5135 O  O   . HOH DA 6 .   ? 5.328   -34.553 46.813  1.000 41.693 0 1187 HOH A O   1 ? 
HETATM 5136 O  O   . HOH DA 6 .   ? -25.511 -29.647 16.070  1.000 48.402 0 1188 HOH A O   1 ? 
HETATM 5137 O  O   . HOH DA 6 .   ? 0.008   -7.092  3.222   1.000 26.733 0 1189 HOH A O   1 ? 
HETATM 5138 O  O   . HOH DA 6 .   ? -26.032 -25.406 16.599  1.000 37.085 0 1190 HOH A O   1 ? 
HETATM 5139 O  O   . HOH DA 6 .   ? -3.834  -14.330 54.264  1.000 24.964 0 1191 HOH A O   1 ? 
HETATM 5140 O  O   . HOH DA 6 .   ? 1.680   -31.323 25.552  1.000 36.991 0 1192 HOH A O   1 ? 
HETATM 5141 O  O   . HOH DA 6 .   ? -25.498 -32.424 20.983  1.000 48.569 0 1193 HOH A O   1 ? 
HETATM 5142 O  O   . HOH DA 6 .   ? -23.907 -4.063  35.005  1.000 30.964 0 1194 HOH A O   1 ? 
HETATM 5143 O  O   . HOH DA 6 .   ? -4.480  -40.722 31.789  1.000 37.575 0 1195 HOH A O   1 ? 
HETATM 5144 O  O   . HOH DA 6 .   ? -18.703 -37.388 14.360  1.000 44.709 0 1196 HOH A O   1 ? 
HETATM 5145 O  O   . HOH DA 6 .   ? 10.082  -12.216 32.485  1.000 32.966 0 1197 HOH A O   1 ? 
HETATM 5146 O  O   . HOH DA 6 .   ? -29.492 -17.629 25.692  1.000 29.590 0 1198 HOH A O   1 ? 
HETATM 5147 O  O   . HOH DA 6 .   ? -20.962 -16.029 -1.751  1.000 21.063 0 1199 HOH A O   1 ? 
HETATM 5148 O  O   . HOH DA 6 .   ? -0.390  -29.101 49.591  1.000 41.651 0 1200 HOH A O   1 ? 
HETATM 5149 O  O   . HOH DA 6 .   ? -13.783 -16.681 61.667  1.000 32.694 0 1201 HOH A O   1 ? 
HETATM 5150 O  O   . HOH DA 6 .   ? -30.980 -4.876  40.499  1.000 52.370 0 1202 HOH A O   1 ? 
HETATM 5151 O  O   . HOH DA 6 .   ? -17.208 2.691   13.569  1.000 35.827 0 1203 HOH A O   1 ? 
HETATM 5152 O  O   . HOH DA 6 .   ? 5.879   -22.582 -2.767  1.000 29.887 0 1204 HOH A O   1 ? 
HETATM 5153 O  O   . HOH DA 6 .   ? -2.992  -20.928 22.628  1.000 18.314 0 1205 HOH A O   1 ? 
HETATM 5154 O  O   . HOH DA 6 .   ? -18.671 -27.352 37.559  1.000 23.473 0 1206 HOH A O   1 ? 
HETATM 5155 O  O   . HOH DA 6 .   ? -13.385 -4.205  -10.677 1.000 61.660 0 1207 HOH A O   1 ? 
HETATM 5156 O  O   . HOH DA 6 .   ? 9.410   -13.196 18.544  1.000 28.978 0 1208 HOH A O   1 ? 
HETATM 5157 O  O   . HOH DA 6 .   ? -15.467 -2.540  41.206  1.000 52.263 0 1209 HOH A O   1 ? 
HETATM 5158 O  O   . HOH DA 6 .   ? -6.197  -49.290 14.895  1.000 51.681 0 1210 HOH A O   1 ? 
HETATM 5159 O  O   . HOH DA 6 .   ? -4.229  -34.769 54.920  1.000 41.887 0 1211 HOH A O   1 ? 
HETATM 5160 O  O   . HOH DA 6 .   ? 6.775   -36.609 39.593  1.000 50.518 0 1212 HOH A O   1 ? 
HETATM 5161 O  O   . HOH DA 6 .   ? -21.864 -14.435 -7.606  1.000 49.505 0 1213 HOH A O   1 ? 
HETATM 5162 O  O   . HOH DA 6 .   ? -14.464 -13.662 -13.205 1.000 32.762 0 1214 HOH A O   1 ? 
HETATM 5163 O  O   . HOH DA 6 .   ? -2.966  -39.084 18.341  1.000 45.913 0 1215 HOH A O   1 ? 
HETATM 5164 O  O   . HOH DA 6 .   ? 0.835   6.465   -3.295  1.000 46.406 0 1216 HOH A O   1 ? 
HETATM 5165 O  O   . HOH DA 6 .   ? -10.983 -30.609 35.420  1.000 36.161 0 1217 HOH A O   1 ? 
HETATM 5166 O  O   . HOH DA 6 .   ? -15.392 -20.086 -15.761 1.000 23.841 0 1218 HOH A O   1 ? 
HETATM 5167 O  O   . HOH DA 6 .   ? -5.343  3.534   17.532  1.000 52.225 0 1219 HOH A O   1 ? 
HETATM 5168 O  O   . HOH DA 6 .   ? 6.521   -32.499 11.961  1.000 34.638 0 1220 HOH A O   1 ? 
HETATM 5169 O  O   . HOH DA 6 .   ? -2.116  -10.233 46.684  1.000 31.045 0 1221 HOH A O   1 ? 
HETATM 5170 O  O   . HOH DA 6 .   ? 3.426   -14.421 50.298  1.000 34.513 0 1222 HOH A O   1 ? 
HETATM 5171 O  O   . HOH DA 6 .   ? 11.706  -14.436 33.017  1.000 46.216 0 1223 HOH A O   1 ? 
HETATM 5172 O  O   . HOH DA 6 .   ? 1.024   -37.703 35.163  1.000 27.711 0 1224 HOH A O   1 ? 
HETATM 5173 O  O   . HOH DA 6 .   ? 4.721   -30.308 25.617  1.000 37.221 0 1225 HOH A O   1 ? 
HETATM 5174 O  O   . HOH DA 6 .   ? -11.258 -22.603 33.854  1.000 31.074 0 1226 HOH A O   1 ? 
HETATM 5175 O  O   . HOH DA 6 .   ? -16.192 -2.524  48.440  1.000 27.843 0 1227 HOH A O   1 ? 
HETATM 5176 O  O   . HOH DA 6 .   ? -15.897 -35.072 -0.962  1.000 40.265 0 1228 HOH A O   1 ? 
HETATM 5177 O  O   . HOH DA 6 .   ? 8.481   -33.541 -7.346  1.000 43.253 0 1229 HOH A O   1 ? 
HETATM 5178 O  O   . HOH DA 6 .   ? -13.796 -34.644 36.281  1.000 53.357 0 1230 HOH A O   1 ? 
HETATM 5179 O  O   . HOH DA 6 .   ? -11.976 -22.944 54.977  1.000 47.205 0 1231 HOH A O   1 ? 
HETATM 5180 O  O   . HOH DA 6 .   ? -23.700 -9.275  54.849  1.000 30.333 0 1232 HOH A O   1 ? 
HETATM 5181 O  O   . HOH DA 6 .   ? -27.858 -18.538 21.671  1.000 43.067 0 1233 HOH A O   1 ? 
HETATM 5182 O  O   . HOH DA 6 .   ? -28.847 -24.323 -12.089 1.000 48.706 0 1234 HOH A O   1 ? 
HETATM 5183 O  O   . HOH DA 6 .   ? 3.113   -0.117  21.698  1.000 36.036 0 1235 HOH A O   1 ? 
HETATM 5184 O  O   . HOH DA 6 .   ? -23.224 -41.022 30.748  1.000 45.535 0 1236 HOH A O   1 ? 
HETATM 5185 O  O   . HOH DA 6 .   ? -23.368 -7.727  27.595  1.000 41.927 0 1237 HOH A O   1 ? 
HETATM 5186 O  O   . HOH DA 6 .   ? 3.205   -18.770 -7.619  1.000 36.953 0 1238 HOH A O   1 ? 
HETATM 5187 O  O   . HOH DA 6 .   ? -23.036 -17.040 -0.266  1.000 34.833 0 1239 HOH A O   1 ? 
HETATM 5188 O  O   . HOH DA 6 .   ? -7.141  -9.083  25.743  1.000 30.809 0 1240 HOH A O   1 ? 
HETATM 5189 O  O   . HOH DA 6 .   ? -15.770 -39.730 31.223  1.000 21.723 0 1241 HOH A O   1 ? 
HETATM 5190 O  O   . HOH DA 6 .   ? -28.361 -35.588 30.301  1.000 37.391 0 1242 HOH A O   1 ? 
HETATM 5191 O  O   . HOH DA 6 .   ? -5.919  -37.038 -7.382  1.000 30.759 0 1243 HOH A O   1 ? 
HETATM 5192 O  O   . HOH DA 6 .   ? -10.852 -27.461 52.951  1.000 38.189 0 1244 HOH A O   1 ? 
HETATM 5193 O  O   . HOH DA 6 .   ? -28.151 -34.314 42.042  1.000 47.875 0 1245 HOH A O   1 ? 
HETATM 5194 O  O   . HOH DA 6 .   ? -22.805 -27.176 49.386  1.000 51.942 0 1246 HOH A O   1 ? 
HETATM 5195 O  O   . HOH DA 6 .   ? 3.903   -11.326 38.751  1.000 49.206 0 1247 HOH A O   1 ? 
HETATM 5196 O  O   . HOH DA 6 .   ? -17.712 -27.427 -18.418 1.000 36.193 0 1248 HOH A O   1 ? 
HETATM 5197 O  O   . HOH DA 6 .   ? 6.328   -22.041 15.904  1.000 34.420 0 1249 HOH A O   1 ? 
HETATM 5198 O  O   . HOH DA 6 .   ? 6.172   -52.290 20.959  1.000 11.575 0 1250 HOH A O   1 ? 
HETATM 5199 O  O   . HOH DA 6 .   ? 0.059   -1.299  0.860   1.000 33.185 0 1251 HOH A O   1 ? 
HETATM 5200 O  O   . HOH DA 6 .   ? -11.027 -8.840  20.475  1.000 37.420 0 1252 HOH A O   1 ? 
HETATM 5201 O  O   . HOH DA 6 .   ? -0.049  -47.299 13.737  1.000 37.359 0 1253 HOH A O   1 ? 
HETATM 5202 O  O   . HOH DA 6 .   ? -25.360 -41.618 21.638  1.000 54.791 0 1254 HOH A O   1 ? 
HETATM 5203 O  O   . HOH DA 6 .   ? -8.339  -10.459 28.306  1.000 33.634 0 1255 HOH A O   1 ? 
HETATM 5204 O  O   . HOH DA 6 .   ? 12.085  -24.979 4.264   1.000 43.377 0 1256 HOH A O   1 ? 
HETATM 5205 O  O   . HOH DA 6 .   ? -25.232 -29.983 -6.297  1.000 39.550 0 1257 HOH A O   1 ? 
HETATM 5206 O  O   . HOH DA 6 .   ? -26.025 -27.863 -4.761  1.000 58.646 0 1258 HOH A O   1 ? 
HETATM 5207 O  O   . HOH DA 6 .   ? 12.220  -26.396 8.626   1.000 59.876 0 1259 HOH A O   1 ? 
HETATM 5208 O  O   . HOH DA 6 .   ? -25.893 -11.658 17.017  1.000 47.008 0 1260 HOH A O   1 ? 
HETATM 5209 O  O   . HOH DA 6 .   ? -0.097  -6.599  39.325  1.000 40.715 0 1261 HOH A O   1 ? 
HETATM 5210 O  O   . HOH DA 6 .   ? -5.487  -37.227 50.924  1.000 52.243 0 1262 HOH A O   1 ? 
HETATM 5211 O  O   . HOH DA 6 .   ? -24.480 -27.461 45.891  1.000 34.614 0 1263 HOH A O   1 ? 
HETATM 5212 O  O   . HOH DA 6 .   ? -10.401 -29.436 -21.231 1.000 52.434 0 1264 HOH A O   1 ? 
HETATM 5213 O  O   . HOH DA 6 .   ? 7.616   -19.707 17.536  1.000 32.548 0 1265 HOH A O   1 ? 
HETATM 5214 O  O   . HOH DA 6 .   ? 11.177  -33.387 -2.964  1.000 57.572 0 1266 HOH A O   1 ? 
HETATM 5215 O  O   . HOH DA 6 .   ? 15.360  -10.800 10.815  1.000 47.496 0 1267 HOH A O   1 ? 
HETATM 5216 O  O   . HOH DA 6 .   ? 6.677   -3.973  30.459  1.000 49.872 0 1268 HOH A O   1 ? 
HETATM 5217 O  O   . HOH DA 6 .   ? 3.777   -12.967 1.193   1.000 31.676 0 1269 HOH A O   1 ? 
HETATM 5218 O  O   . HOH DA 6 .   ? -21.868 -7.980  29.451  1.000 27.748 0 1270 HOH A O   1 ? 
HETATM 5219 O  O   . HOH DA 6 .   ? -19.442 -33.058 1.996   1.000 41.419 0 1271 HOH A O   1 ? 
HETATM 5220 O  O   . HOH DA 6 .   ? 1.198   0.791   19.952  1.000 36.377 0 1272 HOH A O   1 ? 
HETATM 5221 O  O   . HOH DA 6 .   ? -17.862 -34.189 -9.158  1.000 45.922 0 1273 HOH A O   1 ? 
HETATM 5222 O  O   . HOH DA 6 .   ? -14.541 -11.437 61.819  1.000 42.004 0 1274 HOH A O   1 ? 
HETATM 5223 O  O   . HOH DA 6 .   ? -22.771 -29.605 -4.674  1.000 41.097 0 1275 HOH A O   1 ? 
HETATM 5224 O  O   . HOH DA 6 .   ? 16.701  -45.297 17.514  1.000 39.122 0 1276 HOH A O   1 ? 
HETATM 5225 O  O   . HOH DA 6 .   ? -26.539 -29.993 -16.286 1.000 45.884 0 1277 HOH A O   1 ? 
HETATM 5226 O  O   . HOH DA 6 .   ? 8.025   -28.620 15.790  1.000 41.366 0 1278 HOH A O   1 ? 
HETATM 5227 O  O   . HOH DA 6 .   ? -19.578 -32.360 -10.125 1.000 36.129 0 1279 HOH A O   1 ? 
HETATM 5228 O  O   . HOH DA 6 .   ? -9.842  -40.473 1.647   1.000 47.069 0 1280 HOH A O   1 ? 
HETATM 5229 O  O   . HOH DA 6 .   ? 8.527   -12.165 5.285   1.000 38.002 0 1281 HOH A O   1 ? 
HETATM 5230 O  O   . HOH DA 6 .   ? 9.537   -14.550 40.314  1.000 65.440 0 1282 HOH A O   1 ? 
HETATM 5231 O  O   . HOH DA 6 .   ? -25.524 -25.059 -2.746  1.000 56.473 0 1283 HOH A O   1 ? 
HETATM 5232 O  O   . HOH DA 6 .   ? 10.105  -29.246 45.647  1.000 32.998 0 1284 HOH A O   1 ? 
HETATM 5233 O  O   . HOH DA 6 .   ? 5.581   -28.844 23.603  1.000 49.883 0 1285 HOH A O   1 ? 
HETATM 5234 O  O   . HOH DA 6 .   ? 8.177   -1.752  27.094  1.000 49.728 0 1286 HOH A O   1 ? 
HETATM 5235 O  O   . HOH DA 6 .   ? -8.649  -16.012 13.051  1.000 21.885 0 1287 HOH A O   1 ? 
HETATM 5236 O  O   . HOH DA 6 .   ? -31.882 -13.883 51.453  1.000 40.453 0 1288 HOH A O   1 ? 
HETATM 5237 O  O   . HOH DA 6 .   ? -24.019 -25.290 -18.026 1.000 58.806 0 1289 HOH A O   1 ? 
HETATM 5238 O  O   . HOH DA 6 .   ? 4.592   -3.750  28.233  1.000 44.334 0 1290 HOH A O   1 ? 
HETATM 5239 O  O   . HOH DA 6 .   ? -28.888 -36.449 26.015  1.000 57.980 0 1291 HOH A O   1 ? 
HETATM 5240 O  O   . HOH DA 6 .   ? 3.600   -23.031 52.643  1.000 45.220 0 1292 HOH A O   1 ? 
HETATM 5241 O  O   . HOH DA 6 .   ? 7.977   -26.150 0.100   1.000 37.312 0 1293 HOH A O   1 ? 
HETATM 5242 O  O   . HOH DA 6 .   ? 4.815   -8.012  38.419  1.000 51.465 0 1294 HOH A O   1 ? 
HETATM 5243 O  O   . HOH DA 6 .   ? 3.555   -22.810 -21.353 1.000 46.361 0 1295 HOH A O   1 ? 
HETATM 5244 O  O   . HOH DA 6 .   ? 14.601  -8.265  15.900  1.000 52.225 0 1296 HOH A O   1 ? 
HETATM 5245 O  O   . HOH DA 6 .   ? 7.307   -14.645 16.956  1.000 35.831 0 1297 HOH A O   1 ? 
HETATM 5246 O  O   . HOH DA 6 .   ? -13.848 -0.082  8.066   1.000 20.051 0 1298 HOH A O   1 ? 
HETATM 5247 O  O   . HOH DA 6 .   ? -16.195 3.342   52.646  1.000 40.586 0 1299 HOH A O   1 ? 
HETATM 5248 O  O   . HOH DA 6 .   ? -8.691  -20.513 -18.703 1.000 40.823 0 1300 HOH A O   1 ? 
HETATM 5249 O  O   . HOH DA 6 .   ? -6.573  -5.548  42.203  1.000 28.240 0 1301 HOH A O   1 ? 
HETATM 5250 O  O   . HOH DA 6 .   ? -10.257 2.712   2.798   1.000 30.448 0 1302 HOH A O   1 ? 
HETATM 5251 O  O   . HOH DA 6 .   ? -2.215  -22.849 56.126  1.000 43.483 0 1303 HOH A O   1 ? 
HETATM 5252 O  O   . HOH DA 6 .   ? -11.884 2.465   22.456  1.000 47.401 0 1304 HOH A O   1 ? 
HETATM 5253 O  O   . HOH DA 6 .   ? -13.916 -14.032 -15.721 1.000 42.445 0 1305 HOH A O   1 ? 
HETATM 5254 O  O   . HOH DA 6 .   ? 10.025  -28.998 43.096  1.000 36.026 0 1306 HOH A O   1 ? 
HETATM 5255 O  O   . HOH DA 6 .   ? -24.253 -2.173  56.545  1.000 22.979 0 1307 HOH A O   1 ? 
HETATM 5256 O  O   . HOH DA 6 .   ? -23.936 -23.430 -16.487 1.000 48.099 0 1308 HOH A O   1 ? 
HETATM 5257 O  O   . HOH DA 6 .   ? 13.751  -18.382 31.491  1.000 48.632 0 1309 HOH A O   1 ? 
HETATM 5258 O  O   . HOH DA 6 .   ? -18.728 -33.921 36.526  1.000 44.299 0 1310 HOH A O   1 ? 
HETATM 5259 O  O   . HOH DA 6 .   ? -19.963 -15.166 2.605   1.000 26.287 0 1311 HOH A O   1 ? 
HETATM 5260 O  O   . HOH DA 6 .   ? -22.099 -11.266 8.502   1.000 46.044 0 1312 HOH A O   1 ? 
HETATM 5261 O  O   . HOH DA 6 .   ? -18.980 -7.207  26.353  1.000 38.987 0 1313 HOH A O   1 ? 
HETATM 5262 O  O   . HOH DA 6 .   ? -6.007  -21.288 -18.460 1.000 49.130 0 1314 HOH A O   1 ? 
HETATM 5263 O  O   . HOH DA 6 .   ? 8.562   -23.695 19.247  1.000 50.974 0 1315 HOH A O   1 ? 
HETATM 5264 O  O   . HOH DA 6 .   ? 12.797  -20.114 35.392  1.000 55.641 0 1316 HOH A O   1 ? 
HETATM 5265 O  O   . HOH DA 6 .   ? -0.208  -8.167  43.119  1.000 42.388 0 1317 HOH A O   1 ? 
HETATM 5266 O  O   . HOH DA 6 .   ? -18.589 -4.029  2.130   1.000 35.480 0 1318 HOH A O   1 ? 
HETATM 5267 O  O   . HOH DA 6 .   ? 6.135   -28.259 21.432  1.000 43.375 0 1319 HOH A O   1 ? 
HETATM 5268 O  O   . HOH DA 6 .   ? -23.330 -10.753 10.753  1.000 40.259 0 1320 HOH A O   1 ? 
HETATM 5269 O  O   . HOH DA 6 .   ? 4.088   -10.470 42.844  1.000 47.665 0 1321 HOH A O   1 ? 
HETATM 5270 O  O   . HOH DA 6 .   ? -13.556 2.687   -2.900  1.000 48.258 0 1322 HOH A O   1 ? 
HETATM 5271 O  O   . HOH DA 6 .   ? -28.715 -13.135 24.478  1.000 56.251 0 1323 HOH A O   1 ? 
HETATM 5272 O  O   . HOH DA 6 .   ? 6.149   -24.619 15.086  1.000 31.483 0 1324 HOH A O   1 ? 
HETATM 5273 O  O   . HOH DA 6 .   ? -7.377  -5.469  44.861  1.000 27.647 0 1325 HOH A O   1 ? 
HETATM 5274 O  O   . HOH DA 6 .   ? -29.494 -9.588  45.450  1.000 37.450 0 1326 HOH A O   1 ? 
HETATM 5275 O  O   . HOH DA 6 .   ? 0.272   -8.419  40.323  1.000 44.300 0 1327 HOH A O   1 ? 
HETATM 5276 O  O   . HOH DA 6 .   ? -8.631  -28.873 36.782  1.000 27.684 0 1328 HOH A O   1 ? 
HETATM 5277 O  O   . HOH DA 6 .   ? 14.228  -12.808 10.121  1.000 28.030 0 1329 HOH A O   1 ? 
HETATM 5278 O  O   . HOH DA 6 .   ? -16.316 -35.669 -3.647  1.000 48.332 0 1330 HOH A O   1 ? 
HETATM 5279 O  O   . HOH DA 6 .   ? -36.084 -27.250 32.575  1.000 46.632 0 1331 HOH A O   1 ? 
HETATM 5280 O  O   A HOH DA 6 .   ? -15.681 -10.862 -4.642  0.500 25.343 0 1332 HOH A O   1 ? 
HETATM 5281 O  O   B HOH DA 6 .   ? -16.035 -11.531 -3.033  0.500 28.393 0 1332 HOH A O   1 ? 
HETATM 5282 O  O   . HOH DA 6 .   ? -8.186  -3.534  40.997  1.000 36.449 0 1333 HOH A O   1 ? 
HETATM 5283 O  O   . HOH DA 6 .   ? -13.796 -30.545 41.620  1.000 40.669 0 1334 HOH A O   1 ? 
HETATM 5284 O  O   . HOH DA 6 .   ? -17.073 -20.211 -17.916 1.000 40.197 0 1335 HOH A O   1 ? 
HETATM 5285 O  O   . HOH DA 6 .   ? 13.437  -18.804 26.939  1.000 46.650 0 1336 HOH A O   1 ? 
HETATM 5286 O  O   . HOH DA 6 .   ? -20.787 -12.566 3.767   1.000 30.221 0 1337 HOH A O   1 ? 
HETATM 5287 O  O   . HOH DA 6 .   ? -17.661 -28.291 39.854  1.000 32.282 0 1338 HOH A O   1 ? 
HETATM 5288 O  O   . HOH DA 6 .   ? 12.539  -7.532  22.566  1.000 41.868 0 1339 HOH A O   1 ? 
HETATM 5289 O  O   . HOH DA 6 .   ? 5.573   -36.826 11.855  1.000 55.956 0 1340 HOH A O   1 ? 
HETATM 5290 O  O   . HOH DA 6 .   ? -21.794 -31.939 -0.793  1.000 45.273 0 1341 HOH A O   1 ? 
HETATM 5291 O  O   . HOH DA 6 .   ? -8.932  -41.288 19.147  1.000 42.803 0 1342 HOH A O   1 ? 
HETATM 5292 O  O   . HOH DA 6 .   ? -18.287 -29.743 36.270  1.000 27.210 0 1343 HOH A O   1 ? 
HETATM 5293 O  O   . HOH DA 6 .   ? -25.975 -4.269  50.386  1.000 35.739 0 1344 HOH A O   1 ? 
HETATM 5294 O  O   . HOH DA 6 .   ? 11.280  -4.657  20.072  1.000 45.027 0 1345 HOH A O   1 ? 
HETATM 5295 O  O   . HOH DA 6 .   ? -20.819 -7.993  3.107   1.000 35.619 0 1346 HOH A O   1 ? 
HETATM 5296 O  O   . HOH DA 6 .   ? -18.835 -6.820  2.221   1.000 33.834 0 1347 HOH A O   1 ? 
HETATM 5297 O  O   . HOH DA 6 .   ? -13.199 -24.921 37.694  1.000 28.069 0 1348 HOH A O   1 ? 
HETATM 5298 O  O   . HOH DA 6 .   ? -13.991 -31.791 -18.918 1.000 58.441 0 1349 HOH A O   1 ? 
HETATM 5299 O  O   . HOH DA 6 .   ? 7.331   -20.934 -0.876  1.000 47.901 0 1350 HOH A O   1 ? 
HETATM 5300 O  O   . HOH DA 6 .   ? 15.213  -32.070 -1.240  1.000 40.462 0 1351 HOH A O   1 ? 
HETATM 5301 O  O   . HOH DA 6 .   ? 1.241   -7.905  5.980   1.000 33.016 0 1352 HOH A O   1 ? 
HETATM 5302 O  O   . HOH DA 6 .   ? -23.029 -24.061 12.009  1.000 47.178 0 1353 HOH A O   1 ? 
HETATM 5303 O  O   . HOH DA 6 .   ? -20.818 -0.712  40.442  1.000 51.763 0 1354 HOH A O   1 ? 
HETATM 5304 O  O   . HOH DA 6 .   ? -16.688 -19.183 -13.378 1.000 32.900 0 1355 HOH A O   1 ? 
HETATM 5305 O  O   . HOH DA 6 .   ? -17.988 -17.375 -17.308 1.000 52.399 0 1356 HOH A O   1 ? 
HETATM 5306 O  O   . HOH DA 6 .   ? -7.944  -34.343 53.372  1.000 44.673 0 1357 HOH A O   1 ? 
HETATM 5307 O  O   . HOH DA 6 .   ? -18.162 -7.492  -0.297  1.000 37.318 0 1358 HOH A O   1 ? 
HETATM 5308 O  O   . HOH DA 6 .   ? 7.884   -31.721 18.854  1.000 53.441 0 1359 HOH A O   1 ? 
HETATM 5309 O  O   . HOH DA 6 .   ? -20.070 -33.003 -1.998  1.000 42.836 0 1360 HOH A O   1 ? 
HETATM 5310 O  O   . HOH DA 6 .   ? -3.397  -23.559 -21.764 1.000 40.923 0 1361 HOH A O   1 ? 
HETATM 5311 O  O   . HOH DA 6 .   ? 8.647   -24.243 1.366   1.000 44.093 0 1362 HOH A O   1 ? 
HETATM 5312 O  O   . HOH DA 6 .   ? -28.334 -10.496 30.813  1.000 54.975 0 1363 HOH A O   1 ? 
HETATM 5313 O  O   . HOH DA 6 .   ? -11.313 -29.581 54.601  1.000 46.347 0 1364 HOH A O   1 ? 
HETATM 5314 O  O   . HOH DA 6 .   ? -12.848 -20.787 59.754  1.000 48.845 0 1365 HOH A O   1 ? 
HETATM 5315 O  O   . HOH DA 6 .   ? -17.599 0.034   34.582  1.000 48.272 0 1366 HOH A O   1 ? 
# 
