data_9EJI
# 
_entry.id   9EJI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EJI         pdb_00009eji 10.2210/pdb9eji/pdb 
WWPDB D_1000290631 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-26 ? 
2 'Structure model' 1 1 2025-04-02 ? 
3 'Structure model' 1 2 2025-05-21 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 3 'Structure model' citation        
3 3 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.title'                   
2  3 'Structure model' '_citation.country'                 
3  3 'Structure model' '_citation.journal_abbrev'          
4  3 'Structure model' '_citation.journal_id_CSD'          
5  3 'Structure model' '_citation.journal_id_ISSN'         
6  3 'Structure model' '_citation.journal_volume'          
7  3 'Structure model' '_citation.page_first'              
8  3 'Structure model' '_citation.page_last'               
9  3 'Structure model' '_citation.pdbx_database_id_DOI'    
10 3 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 3 'Structure model' '_citation.title'                   
12 3 'Structure model' '_citation.year'                    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EJI 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 9EJG unspecified 
PDB . 9EJH unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jamie.rossjohn@monash.edu 
_pdbx_contact_author.name_first         Jamie 
_pdbx_contact_author.name_last          Rossjohn 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2020-7522 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lim, J.J.'    1 ? 
'Loh, T.J.'    2 ? 
'Reid, H.H.'   3 ? 
'Rossjohn, J.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                3330 
_citation.page_last                 3330 
_citation.title                     
'A naturally selected alpha beta T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-58690-w 
_citation.pdbx_database_id_PubMed   40199885 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lim, J.J.'      1 0000-0002-6097-6238 
primary 'Jones, C.M.'    2 0000-0001-8594-9554 
primary 'Loh, T.J.'      3 0000-0001-8470-6868 
primary 'Dao, H.T.'      4 ?                   
primary 'Tran, M.T.'     5 ?                   
primary 'Tye-Din, J.A.'  6 0000-0001-7687-9654 
primary 'La Gruta, N.L.' 7 0000-0001-5358-9363 
primary 'Rossjohn, J.'   8 0000-0002-2020-7522 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1  polymer     man 'HLA class II histocompatibility antigen DQ alpha chain'                                  20951.402 1   ? ? ? ? 
2  polymer     man 'HLA class II histocompatibility antigen DQ beta chain'                                   22839.727 1   ? ? ? ? 
3  polymer     man 'glut-L1 peptide'                                                                         1419.533  1   ? ? ? ? 
4  polymer     man 'G9 T cell receptor alpha chain'                                                          22841.359 1   ? ? ? ? 
5  polymer     man 'G9 T cell receptor beta chain'                                                           27296.340 1   ? ? ? ? 
6  branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   1   ? ? ? ? 
7  non-polymer syn GLYCEROL                                                                                  92.094    2   ? ? ? ? 
8  non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                                                  221.208   1   ? ? ? ? 
9  non-polymer syn 'ACETATE ION'                                                                             59.044    3   ? ? ? ? 
10 water       nat water                                                                                     18.015    524 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'HLA-DQA1 protein,MHC class II antigen,Major histocompatibility complex,class II,DQ alpha 1' 
2 'MHC class II antigen'                                                                       
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYVDLERKETVWKLPLFHRLRFDPQFALTNIAVLKHNLNILIKRSN
STAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD
EIYDCKVEHWGLDEPLLKHWEPET
;
;EDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYVDLERKETVWKLPLFHRLRFDPQFALTNIAVLKHNLNILIKRSN
STAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD
EIYDCKVEHWGLDEPLLKHWEPET
;
A ? 
2 'polypeptide(L)' no no 
;RDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCR
HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQ
;
;RDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCR
HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQ
;
B ? 
3 'polypeptide(L)' no no QPPASEQEQPVLP QPPASEQEQPVLP C ? 
4 'polypeptide(L)' no no 
;MQRKEVEQDPGPFNVPEGATVAFNCTYSNSASQSFFWYRQDCRKEPKLLMSVYSSGNEDGRFTAQLNRASQYISLLIRDS
KLSDSATYLCVVMGFQKLVFGTGTRLLVSPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVL
DMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS
;
;MQRKEVEQDPGPFNVPEGATVAFNCTYSNSASQSFFWYRQDCRKEPKLLMSVYSSGNEDGRFTAQLNRASQYISLLIRDS
KLSDSATYLCVVMGFQKLVFGTGTRLLVSPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVL
DMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS
;
D ? 
5 'polypeptide(L)' no no 
;MGVTQTPRYLIKTRGQQVTLSCSPISGHRSVSWYQQTPGQGLQFLFEYFSETQRNKGNFPGRFSGRQFSNSRSEMNVSTL
ELGDSALYLCASSLRAESGELFFGEGSRLTVLEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHVELSWWVN
GKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGR
AD
;
;MGVTQTPRYLIKTRGQQVTLSCSPISGHRSVSWYQQTPGQGLQFLFEYFSETQRNKGNFPGRFSGRQFSNSRSEMNVSTL
ELGDSALYLCASSLRAESGELFFGEGSRLTVLEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHVELSWWVN
GKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGR
AD
;
E ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
7  GLYCEROL                                 GOL 
8  2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
9  'ACETATE ION'                            ACT 
10 water                                    HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   ASP n 
1 3   ILE n 
1 4   VAL n 
1 5   ALA n 
1 6   ASP n 
1 7   HIS n 
1 8   VAL n 
1 9   ALA n 
1 10  SER n 
1 11  TYR n 
1 12  GLY n 
1 13  VAL n 
1 14  ASN n 
1 15  LEU n 
1 16  TYR n 
1 17  GLN n 
1 18  SER n 
1 19  TYR n 
1 20  GLY n 
1 21  PRO n 
1 22  SER n 
1 23  GLY n 
1 24  GLN n 
1 25  PHE n 
1 26  THR n 
1 27  HIS n 
1 28  GLU n 
1 29  PHE n 
1 30  ASP n 
1 31  GLY n 
1 32  ASP n 
1 33  GLU n 
1 34  GLU n 
1 35  PHE n 
1 36  TYR n 
1 37  VAL n 
1 38  ASP n 
1 39  LEU n 
1 40  GLU n 
1 41  ARG n 
1 42  LYS n 
1 43  GLU n 
1 44  THR n 
1 45  VAL n 
1 46  TRP n 
1 47  LYS n 
1 48  LEU n 
1 49  PRO n 
1 50  LEU n 
1 51  PHE n 
1 52  HIS n 
1 53  ARG n 
1 54  LEU n 
1 55  ARG n 
1 56  PHE n 
1 57  ASP n 
1 58  PRO n 
1 59  GLN n 
1 60  PHE n 
1 61  ALA n 
1 62  LEU n 
1 63  THR n 
1 64  ASN n 
1 65  ILE n 
1 66  ALA n 
1 67  VAL n 
1 68  LEU n 
1 69  LYS n 
1 70  HIS n 
1 71  ASN n 
1 72  LEU n 
1 73  ASN n 
1 74  ILE n 
1 75  LEU n 
1 76  ILE n 
1 77  LYS n 
1 78  ARG n 
1 79  SER n 
1 80  ASN n 
1 81  SER n 
1 82  THR n 
1 83  ALA n 
1 84  ALA n 
1 85  THR n 
1 86  ASN n 
1 87  GLU n 
1 88  VAL n 
1 89  PRO n 
1 90  GLU n 
1 91  VAL n 
1 92  THR n 
1 93  VAL n 
1 94  PHE n 
1 95  SER n 
1 96  LYS n 
1 97  SER n 
1 98  PRO n 
1 99  VAL n 
1 100 THR n 
1 101 LEU n 
1 102 GLY n 
1 103 GLN n 
1 104 PRO n 
1 105 ASN n 
1 106 THR n 
1 107 LEU n 
1 108 ILE n 
1 109 CYS n 
1 110 LEU n 
1 111 VAL n 
1 112 ASP n 
1 113 ASN n 
1 114 ILE n 
1 115 PHE n 
1 116 PRO n 
1 117 PRO n 
1 118 VAL n 
1 119 VAL n 
1 120 ASN n 
1 121 ILE n 
1 122 THR n 
1 123 TRP n 
1 124 LEU n 
1 125 SER n 
1 126 ASN n 
1 127 GLY n 
1 128 HIS n 
1 129 SER n 
1 130 VAL n 
1 131 THR n 
1 132 GLU n 
1 133 GLY n 
1 134 VAL n 
1 135 SER n 
1 136 GLU n 
1 137 THR n 
1 138 SER n 
1 139 PHE n 
1 140 LEU n 
1 141 SER n 
1 142 LYS n 
1 143 SER n 
1 144 ASP n 
1 145 HIS n 
1 146 SER n 
1 147 PHE n 
1 148 PHE n 
1 149 LYS n 
1 150 ILE n 
1 151 SER n 
1 152 TYR n 
1 153 LEU n 
1 154 THR n 
1 155 PHE n 
1 156 LEU n 
1 157 PRO n 
1 158 SER n 
1 159 ALA n 
1 160 ASP n 
1 161 GLU n 
1 162 ILE n 
1 163 TYR n 
1 164 ASP n 
1 165 CYS n 
1 166 LYS n 
1 167 VAL n 
1 168 GLU n 
1 169 HIS n 
1 170 TRP n 
1 171 GLY n 
1 172 LEU n 
1 173 ASP n 
1 174 GLU n 
1 175 PRO n 
1 176 LEU n 
1 177 LEU n 
1 178 LYS n 
1 179 HIS n 
1 180 TRP n 
1 181 GLU n 
1 182 PRO n 
1 183 GLU n 
1 184 THR n 
2 1   ARG n 
2 2   ASP n 
2 3   SER n 
2 4   PRO n 
2 5   GLU n 
2 6   ASP n 
2 7   PHE n 
2 8   VAL n 
2 9   TYR n 
2 10  GLN n 
2 11  PHE n 
2 12  LYS n 
2 13  GLY n 
2 14  MET n 
2 15  CYS n 
2 16  TYR n 
2 17  PHE n 
2 18  THR n 
2 19  ASN n 
2 20  GLY n 
2 21  THR n 
2 22  GLU n 
2 23  ARG n 
2 24  VAL n 
2 25  ARG n 
2 26  LEU n 
2 27  VAL n 
2 28  SER n 
2 29  ARG n 
2 30  SER n 
2 31  ILE n 
2 32  TYR n 
2 33  ASN n 
2 34  ARG n 
2 35  GLU n 
2 36  GLU n 
2 37  ILE n 
2 38  VAL n 
2 39  ARG n 
2 40  PHE n 
2 41  ASP n 
2 42  SER n 
2 43  ASP n 
2 44  VAL n 
2 45  GLY n 
2 46  GLU n 
2 47  PHE n 
2 48  ARG n 
2 49  ALA n 
2 50  VAL n 
2 51  THR n 
2 52  LEU n 
2 53  LEU n 
2 54  GLY n 
2 55  LEU n 
2 56  PRO n 
2 57  ALA n 
2 58  ALA n 
2 59  GLU n 
2 60  TYR n 
2 61  TRP n 
2 62  ASN n 
2 63  SER n 
2 64  GLN n 
2 65  LYS n 
2 66  ASP n 
2 67  ILE n 
2 68  LEU n 
2 69  GLU n 
2 70  ARG n 
2 71  LYS n 
2 72  ARG n 
2 73  ALA n 
2 74  ALA n 
2 75  VAL n 
2 76  ASP n 
2 77  ARG n 
2 78  VAL n 
2 79  CYS n 
2 80  ARG n 
2 81  HIS n 
2 82  ASN n 
2 83  TYR n 
2 84  GLN n 
2 85  LEU n 
2 86  GLU n 
2 87  LEU n 
2 88  ARG n 
2 89  THR n 
2 90  THR n 
2 91  LEU n 
2 92  GLN n 
2 93  ARG n 
2 94  ARG n 
2 95  VAL n 
2 96  GLU n 
2 97  PRO n 
2 98  THR n 
2 99  VAL n 
2 100 THR n 
2 101 ILE n 
2 102 SER n 
2 103 PRO n 
2 104 SER n 
2 105 ARG n 
2 106 THR n 
2 107 GLU n 
2 108 ALA n 
2 109 LEU n 
2 110 ASN n 
2 111 HIS n 
2 112 HIS n 
2 113 ASN n 
2 114 LEU n 
2 115 LEU n 
2 116 VAL n 
2 117 CYS n 
2 118 SER n 
2 119 VAL n 
2 120 THR n 
2 121 ASP n 
2 122 PHE n 
2 123 TYR n 
2 124 PRO n 
2 125 ALA n 
2 126 GLN n 
2 127 ILE n 
2 128 LYS n 
2 129 VAL n 
2 130 ARG n 
2 131 TRP n 
2 132 PHE n 
2 133 ARG n 
2 134 ASN n 
2 135 GLY n 
2 136 GLN n 
2 137 GLU n 
2 138 GLU n 
2 139 THR n 
2 140 ALA n 
2 141 GLY n 
2 142 VAL n 
2 143 VAL n 
2 144 SER n 
2 145 THR n 
2 146 PRO n 
2 147 LEU n 
2 148 ILE n 
2 149 ARG n 
2 150 ASN n 
2 151 GLY n 
2 152 ASP n 
2 153 TRP n 
2 154 THR n 
2 155 PHE n 
2 156 GLN n 
2 157 ILE n 
2 158 LEU n 
2 159 VAL n 
2 160 MET n 
2 161 LEU n 
2 162 GLU n 
2 163 MET n 
2 164 THR n 
2 165 PRO n 
2 166 GLN n 
2 167 ARG n 
2 168 GLY n 
2 169 ASP n 
2 170 VAL n 
2 171 TYR n 
2 172 THR n 
2 173 CYS n 
2 174 HIS n 
2 175 VAL n 
2 176 GLU n 
2 177 HIS n 
2 178 PRO n 
2 179 SER n 
2 180 LEU n 
2 181 GLN n 
2 182 SER n 
2 183 PRO n 
2 184 ILE n 
2 185 THR n 
2 186 VAL n 
2 187 GLU n 
2 188 TRP n 
2 189 ARG n 
2 190 ALA n 
2 191 GLN n 
2 192 SER n 
2 193 GLU n 
2 194 SER n 
2 195 ALA n 
2 196 GLN n 
3 1   GLN n 
3 2   PRO n 
3 3   PRO n 
3 4   ALA n 
3 5   SER n 
3 6   GLU n 
3 7   GLN n 
3 8   GLU n 
3 9   GLN n 
3 10  PRO n 
3 11  VAL n 
3 12  LEU n 
3 13  PRO n 
4 1   MET n 
4 2   GLN n 
4 3   ARG n 
4 4   LYS n 
4 5   GLU n 
4 6   VAL n 
4 7   GLU n 
4 8   GLN n 
4 9   ASP n 
4 10  PRO n 
4 11  GLY n 
4 12  PRO n 
4 13  PHE n 
4 14  ASN n 
4 15  VAL n 
4 16  PRO n 
4 17  GLU n 
4 18  GLY n 
4 19  ALA n 
4 20  THR n 
4 21  VAL n 
4 22  ALA n 
4 23  PHE n 
4 24  ASN n 
4 25  CYS n 
4 26  THR n 
4 27  TYR n 
4 28  SER n 
4 29  ASN n 
4 30  SER n 
4 31  ALA n 
4 32  SER n 
4 33  GLN n 
4 34  SER n 
4 35  PHE n 
4 36  PHE n 
4 37  TRP n 
4 38  TYR n 
4 39  ARG n 
4 40  GLN n 
4 41  ASP n 
4 42  CYS n 
4 43  ARG n 
4 44  LYS n 
4 45  GLU n 
4 46  PRO n 
4 47  LYS n 
4 48  LEU n 
4 49  LEU n 
4 50  MET n 
4 51  SER n 
4 52  VAL n 
4 53  TYR n 
4 54  SER n 
4 55  SER n 
4 56  GLY n 
4 57  ASN n 
4 58  GLU n 
4 59  ASP n 
4 60  GLY n 
4 61  ARG n 
4 62  PHE n 
4 63  THR n 
4 64  ALA n 
4 65  GLN n 
4 66  LEU n 
4 67  ASN n 
4 68  ARG n 
4 69  ALA n 
4 70  SER n 
4 71  GLN n 
4 72  TYR n 
4 73  ILE n 
4 74  SER n 
4 75  LEU n 
4 76  LEU n 
4 77  ILE n 
4 78  ARG n 
4 79  ASP n 
4 80  SER n 
4 81  LYS n 
4 82  LEU n 
4 83  SER n 
4 84  ASP n 
4 85  SER n 
4 86  ALA n 
4 87  THR n 
4 88  TYR n 
4 89  LEU n 
4 90  CYS n 
4 91  VAL n 
4 92  VAL n 
4 93  MET n 
4 94  GLY n 
4 95  PHE n 
4 96  GLN n 
4 97  LYS n 
4 98  LEU n 
4 99  VAL n 
4 100 PHE n 
4 101 GLY n 
4 102 THR n 
4 103 GLY n 
4 104 THR n 
4 105 ARG n 
4 106 LEU n 
4 107 LEU n 
4 108 VAL n 
4 109 SER n 
4 110 PRO n 
4 111 ASN n 
4 112 ILE n 
4 113 GLN n 
4 114 ASN n 
4 115 PRO n 
4 116 ASP n 
4 117 PRO n 
4 118 ALA n 
4 119 VAL n 
4 120 TYR n 
4 121 GLN n 
4 122 LEU n 
4 123 ARG n 
4 124 ASP n 
4 125 SER n 
4 126 LYS n 
4 127 SER n 
4 128 SER n 
4 129 ASP n 
4 130 LYS n 
4 131 SER n 
4 132 VAL n 
4 133 CYS n 
4 134 LEU n 
4 135 PHE n 
4 136 THR n 
4 137 ASP n 
4 138 PHE n 
4 139 ASP n 
4 140 SER n 
4 141 GLN n 
4 142 THR n 
4 143 ASN n 
4 144 VAL n 
4 145 SER n 
4 146 GLN n 
4 147 SER n 
4 148 LYS n 
4 149 ASP n 
4 150 SER n 
4 151 ASP n 
4 152 VAL n 
4 153 TYR n 
4 154 ILE n 
4 155 THR n 
4 156 ASP n 
4 157 LYS n 
4 158 CYS n 
4 159 VAL n 
4 160 LEU n 
4 161 ASP n 
4 162 MET n 
4 163 ARG n 
4 164 SER n 
4 165 MET n 
4 166 ASP n 
4 167 PHE n 
4 168 LYS n 
4 169 SER n 
4 170 ASN n 
4 171 SER n 
4 172 ALA n 
4 173 VAL n 
4 174 ALA n 
4 175 TRP n 
4 176 SER n 
4 177 ASN n 
4 178 LYS n 
4 179 SER n 
4 180 ASP n 
4 181 PHE n 
4 182 ALA n 
4 183 CYS n 
4 184 ALA n 
4 185 ASN n 
4 186 ALA n 
4 187 PHE n 
4 188 ASN n 
4 189 ASN n 
4 190 SER n 
4 191 ILE n 
4 192 ILE n 
4 193 PRO n 
4 194 GLU n 
4 195 ASP n 
4 196 THR n 
4 197 PHE n 
4 198 PHE n 
4 199 PRO n 
4 200 SER n 
4 201 PRO n 
4 202 GLU n 
4 203 SER n 
4 204 SER n 
5 1   MET n 
5 2   GLY n 
5 3   VAL n 
5 4   THR n 
5 5   GLN n 
5 6   THR n 
5 7   PRO n 
5 8   ARG n 
5 9   TYR n 
5 10  LEU n 
5 11  ILE n 
5 12  LYS n 
5 13  THR n 
5 14  ARG n 
5 15  GLY n 
5 16  GLN n 
5 17  GLN n 
5 18  VAL n 
5 19  THR n 
5 20  LEU n 
5 21  SER n 
5 22  CYS n 
5 23  SER n 
5 24  PRO n 
5 25  ILE n 
5 26  SER n 
5 27  GLY n 
5 28  HIS n 
5 29  ARG n 
5 30  SER n 
5 31  VAL n 
5 32  SER n 
5 33  TRP n 
5 34  TYR n 
5 35  GLN n 
5 36  GLN n 
5 37  THR n 
5 38  PRO n 
5 39  GLY n 
5 40  GLN n 
5 41  GLY n 
5 42  LEU n 
5 43  GLN n 
5 44  PHE n 
5 45  LEU n 
5 46  PHE n 
5 47  GLU n 
5 48  TYR n 
5 49  PHE n 
5 50  SER n 
5 51  GLU n 
5 52  THR n 
5 53  GLN n 
5 54  ARG n 
5 55  ASN n 
5 56  LYS n 
5 57  GLY n 
5 58  ASN n 
5 59  PHE n 
5 60  PRO n 
5 61  GLY n 
5 62  ARG n 
5 63  PHE n 
5 64  SER n 
5 65  GLY n 
5 66  ARG n 
5 67  GLN n 
5 68  PHE n 
5 69  SER n 
5 70  ASN n 
5 71  SER n 
5 72  ARG n 
5 73  SER n 
5 74  GLU n 
5 75  MET n 
5 76  ASN n 
5 77  VAL n 
5 78  SER n 
5 79  THR n 
5 80  LEU n 
5 81  GLU n 
5 82  LEU n 
5 83  GLY n 
5 84  ASP n 
5 85  SER n 
5 86  ALA n 
5 87  LEU n 
5 88  TYR n 
5 89  LEU n 
5 90  CYS n 
5 91  ALA n 
5 92  SER n 
5 93  SER n 
5 94  LEU n 
5 95  ARG n 
5 96  ALA n 
5 97  GLU n 
5 98  SER n 
5 99  GLY n 
5 100 GLU n 
5 101 LEU n 
5 102 PHE n 
5 103 PHE n 
5 104 GLY n 
5 105 GLU n 
5 106 GLY n 
5 107 SER n 
5 108 ARG n 
5 109 LEU n 
5 110 THR n 
5 111 VAL n 
5 112 LEU n 
5 113 GLU n 
5 114 ASP n 
5 115 LEU n 
5 116 ASN n 
5 117 LYS n 
5 118 VAL n 
5 119 PHE n 
5 120 PRO n 
5 121 PRO n 
5 122 GLU n 
5 123 VAL n 
5 124 ALA n 
5 125 VAL n 
5 126 PHE n 
5 127 GLU n 
5 128 PRO n 
5 129 SER n 
5 130 GLU n 
5 131 ALA n 
5 132 GLU n 
5 133 ILE n 
5 134 SER n 
5 135 HIS n 
5 136 THR n 
5 137 GLN n 
5 138 LYS n 
5 139 ALA n 
5 140 THR n 
5 141 LEU n 
5 142 VAL n 
5 143 CYS n 
5 144 LEU n 
5 145 ALA n 
5 146 THR n 
5 147 GLY n 
5 148 PHE n 
5 149 PHE n 
5 150 PRO n 
5 151 ASP n 
5 152 HIS n 
5 153 VAL n 
5 154 GLU n 
5 155 LEU n 
5 156 SER n 
5 157 TRP n 
5 158 TRP n 
5 159 VAL n 
5 160 ASN n 
5 161 GLY n 
5 162 LYS n 
5 163 GLU n 
5 164 VAL n 
5 165 HIS n 
5 166 SER n 
5 167 GLY n 
5 168 VAL n 
5 169 CYS n 
5 170 THR n 
5 171 ASP n 
5 172 PRO n 
5 173 GLN n 
5 174 PRO n 
5 175 LEU n 
5 176 LYS n 
5 177 GLU n 
5 178 GLN n 
5 179 PRO n 
5 180 ALA n 
5 181 LEU n 
5 182 ASN n 
5 183 ASP n 
5 184 SER n 
5 185 ARG n 
5 186 TYR n 
5 187 ALA n 
5 188 LEU n 
5 189 SER n 
5 190 SER n 
5 191 ARG n 
5 192 LEU n 
5 193 ARG n 
5 194 VAL n 
5 195 SER n 
5 196 ALA n 
5 197 THR n 
5 198 PHE n 
5 199 TRP n 
5 200 GLN n 
5 201 ASN n 
5 202 PRO n 
5 203 ARG n 
5 204 ASN n 
5 205 HIS n 
5 206 PHE n 
5 207 ARG n 
5 208 CYS n 
5 209 GLN n 
5 210 VAL n 
5 211 GLN n 
5 212 PHE n 
5 213 TYR n 
5 214 GLY n 
5 215 LEU n 
5 216 SER n 
5 217 GLU n 
5 218 ASN n 
5 219 ASP n 
5 220 GLU n 
5 221 TRP n 
5 222 THR n 
5 223 GLN n 
5 224 ASP n 
5 225 ARG n 
5 226 ALA n 
5 227 LYS n 
5 228 PRO n 
5 229 VAL n 
5 230 THR n 
5 231 GLN n 
5 232 ILE n 
5 233 VAL n 
5 234 SER n 
5 235 ALA n 
5 236 GLU n 
5 237 ALA n 
5 238 TRP n 
5 239 GLY n 
5 240 ARG n 
5 241 ALA n 
5 242 ASP n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 184 human ? HLA-DQA1 ? ? ? ? ? ? 'Homo sapiens'      9606 ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 196 human ? HLA-DQB1 ? ? ? ? ? ? 'Homo sapiens'      9606 ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 13  wheat ? ?        ? ? ? ? ? ? 'Triticum aestivum' 4565 ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 204 human ? ?        ? ? ? ? ? ? 'Homo sapiens'      9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)'                 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 242 human ? ?        ? ? ? ? ? ? 'Homo sapiens'      9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)'                 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   6 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 6 DGlcpNAcb1-4DGlcpNAcb1-                               'Glycam Condensed Sequence' GMML       1.0   
2 6 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 6 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'    LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  6 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ACT non-polymer                  . 'ACETATE ION'                            ? 'C2 H3 O2 -1'    59.044  
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
GOL non-polymer                  . GLYCEROL                                 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       
92.094  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                  . WATER                                    ? 'H2 O'           18.015  
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   -2  ?   ?   ?   A . n 
A 1 2   ASP 2   -1  ?   ?   ?   A . n 
A 1 3   ILE 3   0   0   ILE ILE A . n 
A 1 4   VAL 4   1   1   VAL VAL A . n 
A 1 5   ALA 5   2   2   ALA ALA A . n 
A 1 6   ASP 6   3   3   ASP ASP A . n 
A 1 7   HIS 7   4   4   HIS HIS A . n 
A 1 8   VAL 8   5   5   VAL VAL A . n 
A 1 9   ALA 9   6   6   ALA ALA A . n 
A 1 10  SER 10  7   7   SER SER A . n 
A 1 11  TYR 11  8   8   TYR TYR A . n 
A 1 12  GLY 12  9   9   GLY GLY A . n 
A 1 13  VAL 13  10  10  VAL VAL A . n 
A 1 14  ASN 14  11  11  ASN ASN A . n 
A 1 15  LEU 15  12  12  LEU LEU A . n 
A 1 16  TYR 16  13  13  TYR TYR A . n 
A 1 17  GLN 17  14  14  GLN GLN A . n 
A 1 18  SER 18  15  15  SER SER A . n 
A 1 19  TYR 19  16  16  TYR TYR A . n 
A 1 20  GLY 20  17  17  GLY GLY A . n 
A 1 21  PRO 21  18  18  PRO PRO A . n 
A 1 22  SER 22  19  19  SER SER A . n 
A 1 23  GLY 23  20  20  GLY GLY A . n 
A 1 24  GLN 24  21  21  GLN GLN A . n 
A 1 25  PHE 25  22  22  PHE PHE A . n 
A 1 26  THR 26  23  23  THR THR A . n 
A 1 27  HIS 27  24  24  HIS HIS A . n 
A 1 28  GLU 28  25  25  GLU GLU A . n 
A 1 29  PHE 29  26  26  PHE PHE A . n 
A 1 30  ASP 30  27  27  ASP ASP A . n 
A 1 31  GLY 31  28  28  GLY GLY A . n 
A 1 32  ASP 32  29  29  ASP ASP A . n 
A 1 33  GLU 33  30  30  GLU GLU A . n 
A 1 34  GLU 34  31  31  GLU GLU A . n 
A 1 35  PHE 35  32  32  PHE PHE A . n 
A 1 36  TYR 36  33  33  TYR TYR A . n 
A 1 37  VAL 37  34  34  VAL VAL A . n 
A 1 38  ASP 38  35  35  ASP ASP A . n 
A 1 39  LEU 39  36  36  LEU LEU A . n 
A 1 40  GLU 40  37  37  GLU GLU A . n 
A 1 41  ARG 41  38  38  ARG ARG A . n 
A 1 42  LYS 42  39  39  LYS LYS A . n 
A 1 43  GLU 43  40  40  GLU GLU A . n 
A 1 44  THR 44  41  41  THR THR A . n 
A 1 45  VAL 45  42  42  VAL VAL A . n 
A 1 46  TRP 46  43  43  TRP TRP A . n 
A 1 47  LYS 47  44  44  LYS LYS A . n 
A 1 48  LEU 48  45  45  LEU LEU A . n 
A 1 49  PRO 49  46  46  PRO PRO A . n 
A 1 50  LEU 50  47  47  LEU LEU A . n 
A 1 51  PHE 51  48  48  PHE PHE A . n 
A 1 52  HIS 52  49  49  HIS HIS A . n 
A 1 53  ARG 53  50  50  ARG ARG A . n 
A 1 54  LEU 54  51  51  LEU LEU A . n 
A 1 55  ARG 55  52  52  ARG ARG A . n 
A 1 56  PHE 56  53  53  PHE PHE A . n 
A 1 57  ASP 57  54  54  ASP ASP A . n 
A 1 58  PRO 58  55  55  PRO PRO A . n 
A 1 59  GLN 59  56  56  GLN GLN A . n 
A 1 60  PHE 60  57  57  PHE PHE A . n 
A 1 61  ALA 61  58  58  ALA ALA A . n 
A 1 62  LEU 62  59  59  LEU LEU A . n 
A 1 63  THR 63  60  60  THR THR A . n 
A 1 64  ASN 64  61  61  ASN ASN A . n 
A 1 65  ILE 65  62  62  ILE ILE A . n 
A 1 66  ALA 66  63  63  ALA ALA A . n 
A 1 67  VAL 67  64  64  VAL VAL A . n 
A 1 68  LEU 68  65  65  LEU LEU A . n 
A 1 69  LYS 69  66  66  LYS LYS A . n 
A 1 70  HIS 70  67  67  HIS HIS A . n 
A 1 71  ASN 71  68  68  ASN ASN A . n 
A 1 72  LEU 72  69  69  LEU LEU A . n 
A 1 73  ASN 73  70  70  ASN ASN A . n 
A 1 74  ILE 74  71  71  ILE ILE A . n 
A 1 75  LEU 75  72  72  LEU LEU A . n 
A 1 76  ILE 76  73  73  ILE ILE A . n 
A 1 77  LYS 77  74  74  LYS LYS A . n 
A 1 78  ARG 78  75  75  ARG ARG A . n 
A 1 79  SER 79  76  76  SER SER A . n 
A 1 80  ASN 80  77  77  ASN ASN A . n 
A 1 81  SER 81  78  78  SER SER A . n 
A 1 82  THR 82  79  79  THR THR A . n 
A 1 83  ALA 83  80  80  ALA ALA A . n 
A 1 84  ALA 84  81  81  ALA ALA A . n 
A 1 85  THR 85  82  82  THR THR A . n 
A 1 86  ASN 86  83  83  ASN ASN A . n 
A 1 87  GLU 87  84  84  GLU GLU A . n 
A 1 88  VAL 88  85  85  VAL VAL A . n 
A 1 89  PRO 89  86  86  PRO PRO A . n 
A 1 90  GLU 90  87  87  GLU GLU A . n 
A 1 91  VAL 91  88  88  VAL VAL A . n 
A 1 92  THR 92  89  89  THR THR A . n 
A 1 93  VAL 93  90  90  VAL VAL A . n 
A 1 94  PHE 94  91  91  PHE PHE A . n 
A 1 95  SER 95  92  92  SER SER A . n 
A 1 96  LYS 96  93  93  LYS LYS A . n 
A 1 97  SER 97  94  94  SER SER A . n 
A 1 98  PRO 98  95  95  PRO PRO A . n 
A 1 99  VAL 99  96  96  VAL VAL A . n 
A 1 100 THR 100 97  97  THR THR A . n 
A 1 101 LEU 101 98  98  LEU LEU A . n 
A 1 102 GLY 102 99  99  GLY GLY A . n 
A 1 103 GLN 103 100 100 GLN GLN A . n 
A 1 104 PRO 104 101 101 PRO PRO A . n 
A 1 105 ASN 105 102 102 ASN ASN A . n 
A 1 106 THR 106 103 103 THR THR A . n 
A 1 107 LEU 107 104 104 LEU LEU A . n 
A 1 108 ILE 108 105 105 ILE ILE A . n 
A 1 109 CYS 109 106 106 CYS CYS A . n 
A 1 110 LEU 110 107 107 LEU LEU A . n 
A 1 111 VAL 111 108 108 VAL VAL A . n 
A 1 112 ASP 112 109 109 ASP ASP A . n 
A 1 113 ASN 113 110 110 ASN ASN A . n 
A 1 114 ILE 114 111 111 ILE ILE A . n 
A 1 115 PHE 115 112 112 PHE PHE A . n 
A 1 116 PRO 116 113 113 PRO PRO A . n 
A 1 117 PRO 117 114 114 PRO PRO A . n 
A 1 118 VAL 118 115 115 VAL VAL A . n 
A 1 119 VAL 119 116 116 VAL VAL A . n 
A 1 120 ASN 120 117 117 ASN ASN A . n 
A 1 121 ILE 121 118 118 ILE ILE A . n 
A 1 122 THR 122 119 119 THR THR A . n 
A 1 123 TRP 123 120 120 TRP TRP A . n 
A 1 124 LEU 124 121 121 LEU LEU A . n 
A 1 125 SER 125 122 122 SER SER A . n 
A 1 126 ASN 126 123 123 ASN ASN A . n 
A 1 127 GLY 127 124 124 GLY GLY A . n 
A 1 128 HIS 128 125 125 HIS HIS A . n 
A 1 129 SER 129 126 126 SER SER A . n 
A 1 130 VAL 130 127 127 VAL VAL A . n 
A 1 131 THR 131 128 128 THR THR A . n 
A 1 132 GLU 132 129 129 GLU GLU A . n 
A 1 133 GLY 133 130 130 GLY GLY A . n 
A 1 134 VAL 134 131 131 VAL VAL A . n 
A 1 135 SER 135 132 132 SER SER A . n 
A 1 136 GLU 136 133 133 GLU GLU A . n 
A 1 137 THR 137 134 134 THR THR A . n 
A 1 138 SER 138 135 135 SER SER A . n 
A 1 139 PHE 139 136 136 PHE PHE A . n 
A 1 140 LEU 140 137 137 LEU LEU A . n 
A 1 141 SER 141 138 138 SER SER A . n 
A 1 142 LYS 142 139 139 LYS LYS A . n 
A 1 143 SER 143 140 140 SER SER A . n 
A 1 144 ASP 144 141 141 ASP ASP A . n 
A 1 145 HIS 145 142 142 HIS HIS A . n 
A 1 146 SER 146 143 143 SER SER A . n 
A 1 147 PHE 147 144 144 PHE PHE A . n 
A 1 148 PHE 148 145 145 PHE PHE A . n 
A 1 149 LYS 149 146 146 LYS LYS A . n 
A 1 150 ILE 150 147 147 ILE ILE A . n 
A 1 151 SER 151 148 148 SER SER A . n 
A 1 152 TYR 152 149 149 TYR TYR A . n 
A 1 153 LEU 153 150 150 LEU LEU A . n 
A 1 154 THR 154 151 151 THR THR A . n 
A 1 155 PHE 155 152 152 PHE PHE A . n 
A 1 156 LEU 156 153 153 LEU LEU A . n 
A 1 157 PRO 157 154 154 PRO PRO A . n 
A 1 158 SER 158 155 155 SER SER A . n 
A 1 159 ALA 159 156 156 ALA ALA A . n 
A 1 160 ASP 160 157 157 ASP ASP A . n 
A 1 161 GLU 161 158 158 GLU GLU A . n 
A 1 162 ILE 162 159 159 ILE ILE A . n 
A 1 163 TYR 163 160 160 TYR TYR A . n 
A 1 164 ASP 164 161 161 ASP ASP A . n 
A 1 165 CYS 165 162 162 CYS CYS A . n 
A 1 166 LYS 166 163 163 LYS LYS A . n 
A 1 167 VAL 167 164 164 VAL VAL A . n 
A 1 168 GLU 168 165 165 GLU GLU A . n 
A 1 169 HIS 169 166 166 HIS HIS A . n 
A 1 170 TRP 170 167 167 TRP TRP A . n 
A 1 171 GLY 171 168 168 GLY GLY A . n 
A 1 172 LEU 172 169 169 LEU LEU A . n 
A 1 173 ASP 173 170 170 ASP ASP A . n 
A 1 174 GLU 174 171 171 GLU GLU A . n 
A 1 175 PRO 175 172 172 PRO PRO A . n 
A 1 176 LEU 176 173 173 LEU LEU A . n 
A 1 177 LEU 177 174 174 LEU LEU A . n 
A 1 178 LYS 178 175 175 LYS LYS A . n 
A 1 179 HIS 179 176 176 HIS HIS A . n 
A 1 180 TRP 180 177 177 TRP TRP A . n 
A 1 181 GLU 181 178 178 GLU GLU A . n 
A 1 182 PRO 182 179 179 PRO PRO A . n 
A 1 183 GLU 183 180 180 GLU GLU A . n 
A 1 184 THR 184 181 181 THR THR A . n 
B 2 1   ARG 1   1   ?   ?   ?   B . n 
B 2 2   ASP 2   2   ?   ?   ?   B . n 
B 2 3   SER 3   3   3   SER SER B . n 
B 2 4   PRO 4   4   4   PRO PRO B . n 
B 2 5   GLU 5   5   5   GLU GLU B . n 
B 2 6   ASP 6   6   6   ASP ASP B . n 
B 2 7   PHE 7   7   7   PHE PHE B . n 
B 2 8   VAL 8   8   8   VAL VAL B . n 
B 2 9   TYR 9   9   9   TYR TYR B . n 
B 2 10  GLN 10  10  10  GLN GLN B . n 
B 2 11  PHE 11  11  11  PHE PHE B . n 
B 2 12  LYS 12  12  12  LYS LYS B . n 
B 2 13  GLY 13  13  13  GLY GLY B . n 
B 2 14  MET 14  14  14  MET MET B . n 
B 2 15  CYS 15  15  15  CYS CYS B . n 
B 2 16  TYR 16  16  16  TYR TYR B . n 
B 2 17  PHE 17  17  17  PHE PHE B . n 
B 2 18  THR 18  18  18  THR THR B . n 
B 2 19  ASN 19  19  19  ASN ASN B . n 
B 2 20  GLY 20  20  20  GLY GLY B . n 
B 2 21  THR 21  21  21  THR THR B . n 
B 2 22  GLU 22  22  22  GLU GLU B . n 
B 2 23  ARG 23  23  23  ARG ARG B . n 
B 2 24  VAL 24  24  24  VAL VAL B . n 
B 2 25  ARG 25  25  25  ARG ARG B . n 
B 2 26  LEU 26  26  26  LEU LEU B . n 
B 2 27  VAL 27  27  27  VAL VAL B . n 
B 2 28  SER 28  28  28  SER SER B . n 
B 2 29  ARG 29  29  29  ARG ARG B . n 
B 2 30  SER 30  30  30  SER SER B . n 
B 2 31  ILE 31  31  31  ILE ILE B . n 
B 2 32  TYR 32  32  32  TYR TYR B . n 
B 2 33  ASN 33  33  33  ASN ASN B . n 
B 2 34  ARG 34  34  34  ARG ARG B . n 
B 2 35  GLU 35  35  35  GLU GLU B . n 
B 2 36  GLU 36  36  36  GLU GLU B . n 
B 2 37  ILE 37  37  37  ILE ILE B . n 
B 2 38  VAL 38  38  38  VAL VAL B . n 
B 2 39  ARG 39  39  39  ARG ARG B . n 
B 2 40  PHE 40  40  40  PHE PHE B . n 
B 2 41  ASP 41  41  41  ASP ASP B . n 
B 2 42  SER 42  42  42  SER SER B . n 
B 2 43  ASP 43  43  43  ASP ASP B . n 
B 2 44  VAL 44  44  44  VAL VAL B . n 
B 2 45  GLY 45  45  45  GLY GLY B . n 
B 2 46  GLU 46  46  46  GLU GLU B . n 
B 2 47  PHE 47  47  47  PHE PHE B . n 
B 2 48  ARG 48  48  48  ARG ARG B . n 
B 2 49  ALA 49  49  49  ALA ALA B . n 
B 2 50  VAL 50  50  50  VAL VAL B . n 
B 2 51  THR 51  51  51  THR THR B . n 
B 2 52  LEU 52  52  52  LEU LEU B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  GLY 54  54  54  GLY GLY B . n 
B 2 55  LEU 55  55  55  LEU LEU B . n 
B 2 56  PRO 56  56  56  PRO PRO B . n 
B 2 57  ALA 57  57  57  ALA ALA B . n 
B 2 58  ALA 58  58  58  ALA ALA B . n 
B 2 59  GLU 59  59  59  GLU GLU B . n 
B 2 60  TYR 60  60  60  TYR TYR B . n 
B 2 61  TRP 61  61  61  TRP TRP B . n 
B 2 62  ASN 62  62  62  ASN ASN B . n 
B 2 63  SER 63  63  63  SER SER B . n 
B 2 64  GLN 64  64  64  GLN GLN B . n 
B 2 65  LYS 65  65  65  LYS LYS B . n 
B 2 66  ASP 66  66  66  ASP ASP B . n 
B 2 67  ILE 67  67  67  ILE ILE B . n 
B 2 68  LEU 68  68  68  LEU LEU B . n 
B 2 69  GLU 69  69  69  GLU GLU B . n 
B 2 70  ARG 70  70  70  ARG ARG B . n 
B 2 71  LYS 71  71  71  LYS LYS B . n 
B 2 72  ARG 72  72  72  ARG ARG B . n 
B 2 73  ALA 73  73  73  ALA ALA B . n 
B 2 74  ALA 74  74  74  ALA ALA B . n 
B 2 75  VAL 75  75  75  VAL VAL B . n 
B 2 76  ASP 76  76  76  ASP ASP B . n 
B 2 77  ARG 77  77  77  ARG ARG B . n 
B 2 78  VAL 78  78  78  VAL VAL B . n 
B 2 79  CYS 79  79  79  CYS CYS B . n 
B 2 80  ARG 80  80  80  ARG ARG B . n 
B 2 81  HIS 81  81  81  HIS HIS B . n 
B 2 82  ASN 82  82  82  ASN ASN B . n 
B 2 83  TYR 83  83  83  TYR TYR B . n 
B 2 84  GLN 84  84  84  GLN GLN B . n 
B 2 85  LEU 85  85  85  LEU LEU B . n 
B 2 86  GLU 86  86  86  GLU GLU B . n 
B 2 87  LEU 87  87  87  LEU LEU B . n 
B 2 88  ARG 88  88  88  ARG ARG B . n 
B 2 89  THR 89  89  89  THR THR B . n 
B 2 90  THR 90  90  90  THR THR B . n 
B 2 91  LEU 91  91  91  LEU LEU B . n 
B 2 92  GLN 92  92  92  GLN GLN B . n 
B 2 93  ARG 93  93  93  ARG ARG B . n 
B 2 94  ARG 94  94  94  ARG ARG B . n 
B 2 95  VAL 95  95  95  VAL VAL B . n 
B 2 96  GLU 96  96  96  GLU GLU B . n 
B 2 97  PRO 97  97  97  PRO PRO B . n 
B 2 98  THR 98  98  98  THR THR B . n 
B 2 99  VAL 99  99  99  VAL VAL B . n 
B 2 100 THR 100 100 100 THR THR B . n 
B 2 101 ILE 101 101 101 ILE ILE B . n 
B 2 102 SER 102 102 102 SER SER B . n 
B 2 103 PRO 103 103 103 PRO PRO B . n 
B 2 104 SER 104 104 104 SER SER B . n 
B 2 105 ARG 105 105 ?   ?   ?   B . n 
B 2 106 THR 106 106 ?   ?   ?   B . n 
B 2 107 GLU 107 107 ?   ?   ?   B . n 
B 2 108 ALA 108 108 ?   ?   ?   B . n 
B 2 109 LEU 109 109 ?   ?   ?   B . n 
B 2 110 ASN 110 110 ?   ?   ?   B . n 
B 2 111 HIS 111 111 ?   ?   ?   B . n 
B 2 112 HIS 112 112 ?   ?   ?   B . n 
B 2 113 ASN 113 113 113 ASN ASN B . n 
B 2 114 LEU 114 114 114 LEU LEU B . n 
B 2 115 LEU 115 115 115 LEU LEU B . n 
B 2 116 VAL 116 116 116 VAL VAL B . n 
B 2 117 CYS 117 117 117 CYS CYS B . n 
B 2 118 SER 118 118 118 SER SER B . n 
B 2 119 VAL 119 119 119 VAL VAL B . n 
B 2 120 THR 120 120 120 THR THR B . n 
B 2 121 ASP 121 121 121 ASP ASP B . n 
B 2 122 PHE 122 122 122 PHE PHE B . n 
B 2 123 TYR 123 123 123 TYR TYR B . n 
B 2 124 PRO 124 124 124 PRO PRO B . n 
B 2 125 ALA 125 125 125 ALA ALA B . n 
B 2 126 GLN 126 126 126 GLN GLN B . n 
B 2 127 ILE 127 127 127 ILE ILE B . n 
B 2 128 LYS 128 128 128 LYS LYS B . n 
B 2 129 VAL 129 129 129 VAL VAL B . n 
B 2 130 ARG 130 130 130 ARG ARG B . n 
B 2 131 TRP 131 131 131 TRP TRP B . n 
B 2 132 PHE 132 132 132 PHE PHE B . n 
B 2 133 ARG 133 133 133 ARG ARG B . n 
B 2 134 ASN 134 134 134 ASN ASN B . n 
B 2 135 GLY 135 135 135 GLY GLY B . n 
B 2 136 GLN 136 136 136 GLN GLN B . n 
B 2 137 GLU 137 137 137 GLU GLU B . n 
B 2 138 GLU 138 138 138 GLU GLU B . n 
B 2 139 THR 139 139 139 THR THR B . n 
B 2 140 ALA 140 140 140 ALA ALA B . n 
B 2 141 GLY 141 141 141 GLY GLY B . n 
B 2 142 VAL 142 142 142 VAL VAL B . n 
B 2 143 VAL 143 143 143 VAL VAL B . n 
B 2 144 SER 144 144 144 SER SER B . n 
B 2 145 THR 145 145 145 THR THR B . n 
B 2 146 PRO 146 146 146 PRO PRO B . n 
B 2 147 LEU 147 147 147 LEU LEU B . n 
B 2 148 ILE 148 148 148 ILE ILE B . n 
B 2 149 ARG 149 149 149 ARG ARG B . n 
B 2 150 ASN 150 150 150 ASN ASN B . n 
B 2 151 GLY 151 151 151 GLY GLY B . n 
B 2 152 ASP 152 152 152 ASP ASP B . n 
B 2 153 TRP 153 153 153 TRP TRP B . n 
B 2 154 THR 154 154 154 THR THR B . n 
B 2 155 PHE 155 155 155 PHE PHE B . n 
B 2 156 GLN 156 156 156 GLN GLN B . n 
B 2 157 ILE 157 157 157 ILE ILE B . n 
B 2 158 LEU 158 158 158 LEU LEU B . n 
B 2 159 VAL 159 159 159 VAL VAL B . n 
B 2 160 MET 160 160 160 MET MET B . n 
B 2 161 LEU 161 161 161 LEU LEU B . n 
B 2 162 GLU 162 162 162 GLU GLU B . n 
B 2 163 MET 163 163 163 MET MET B . n 
B 2 164 THR 164 164 164 THR THR B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 GLN 166 166 166 GLN GLN B . n 
B 2 167 ARG 167 167 167 ARG ARG B . n 
B 2 168 GLY 168 168 168 GLY GLY B . n 
B 2 169 ASP 169 169 169 ASP ASP B . n 
B 2 170 VAL 170 170 170 VAL VAL B . n 
B 2 171 TYR 171 171 171 TYR TYR B . n 
B 2 172 THR 172 172 172 THR THR B . n 
B 2 173 CYS 173 173 173 CYS CYS B . n 
B 2 174 HIS 174 174 174 HIS HIS B . n 
B 2 175 VAL 175 175 175 VAL VAL B . n 
B 2 176 GLU 176 176 176 GLU GLU B . n 
B 2 177 HIS 177 177 177 HIS HIS B . n 
B 2 178 PRO 178 178 178 PRO PRO B . n 
B 2 179 SER 179 179 179 SER SER B . n 
B 2 180 LEU 180 180 180 LEU LEU B . n 
B 2 181 GLN 181 181 181 GLN GLN B . n 
B 2 182 SER 182 182 182 SER SER B . n 
B 2 183 PRO 183 183 183 PRO PRO B . n 
B 2 184 ILE 184 184 184 ILE ILE B . n 
B 2 185 THR 185 185 185 THR THR B . n 
B 2 186 VAL 186 186 186 VAL VAL B . n 
B 2 187 GLU 187 187 187 GLU GLU B . n 
B 2 188 TRP 188 188 188 TRP TRP B . n 
B 2 189 ARG 189 189 189 ARG ARG B . n 
B 2 190 ALA 190 189 ?   ?   ?   B A n 
B 2 191 GLN 191 189 ?   ?   ?   B B n 
B 2 192 SER 192 189 ?   ?   ?   B C n 
B 2 193 GLU 193 189 ?   ?   ?   B D n 
B 2 194 SER 194 189 ?   ?   ?   B E n 
B 2 195 ALA 195 193 190 ALA ALA B . n 
B 2 196 GLN 196 194 191 GLN GLN B . n 
C 3 1   GLN 1   0   0   GLN GLN C . n 
C 3 2   PRO 2   1   1   PRO PRO C . n 
C 3 3   PRO 3   2   2   PRO PRO C . n 
C 3 4   ALA 4   3   3   ALA ALA C . n 
C 3 5   SER 5   4   4   SER SER C . n 
C 3 6   GLU 6   5   5   GLU GLU C . n 
C 3 7   GLN 7   6   6   GLN GLN C . n 
C 3 8   GLU 8   7   7   GLU GLU C . n 
C 3 9   GLN 9   8   8   GLN GLN C . n 
C 3 10  PRO 10  9   9   PRO PRO C . n 
C 3 11  VAL 11  10  10  VAL VAL C . n 
C 3 12  LEU 12  11  11  LEU LEU C . n 
C 3 13  PRO 13  12  12  PRO PRO C . n 
D 4 1   MET 1   -1  ?   ?   ?   D . n 
D 4 2   GLN 2   0   ?   ?   ?   D . n 
D 4 3   ARG 3   1   1   ARG ARG D . n 
D 4 4   LYS 4   2   2   LYS LYS D . n 
D 4 5   GLU 5   3   3   GLU GLU D . n 
D 4 6   VAL 6   4   4   VAL VAL D . n 
D 4 7   GLU 7   5   5   GLU GLU D . n 
D 4 8   GLN 8   6   6   GLN GLN D . n 
D 4 9   ASP 9   7   7   ASP ASP D . n 
D 4 10  PRO 10  8   8   PRO PRO D . n 
D 4 11  GLY 11  9   9   GLY GLY D . n 
D 4 12  PRO 12  10  10  PRO PRO D . n 
D 4 13  PHE 13  11  11  PHE PHE D . n 
D 4 14  ASN 14  12  12  ASN ASN D . n 
D 4 15  VAL 15  13  13  VAL VAL D . n 
D 4 16  PRO 16  14  14  PRO PRO D . n 
D 4 17  GLU 17  15  15  GLU GLU D . n 
D 4 18  GLY 18  16  16  GLY GLY D . n 
D 4 19  ALA 19  17  17  ALA ALA D . n 
D 4 20  THR 20  18  18  THR THR D . n 
D 4 21  VAL 21  19  19  VAL VAL D . n 
D 4 22  ALA 22  20  20  ALA ALA D . n 
D 4 23  PHE 23  21  21  PHE PHE D . n 
D 4 24  ASN 24  22  22  ASN ASN D . n 
D 4 25  CYS 25  23  23  CYS CYS D . n 
D 4 26  THR 26  24  24  THR THR D . n 
D 4 27  TYR 27  25  25  TYR TYR D . n 
D 4 28  SER 28  26  26  SER SER D . n 
D 4 29  ASN 29  27  27  ASN ASN D . n 
D 4 30  SER 30  28  28  SER SER D . n 
D 4 31  ALA 31  29  29  ALA ALA D . n 
D 4 32  SER 32  36  36  SER SER D . n 
D 4 33  GLN 33  37  37  GLN GLN D . n 
D 4 34  SER 34  38  38  SER SER D . n 
D 4 35  PHE 35  39  39  PHE PHE D . n 
D 4 36  PHE 36  40  40  PHE PHE D . n 
D 4 37  TRP 37  41  41  TRP TRP D . n 
D 4 38  TYR 38  42  42  TYR TYR D . n 
D 4 39  ARG 39  43  43  ARG ARG D . n 
D 4 40  GLN 40  44  44  GLN GLN D . n 
D 4 41  ASP 41  45  45  ASP ASP D . n 
D 4 42  CYS 42  46  46  CYS CYS D . n 
D 4 43  ARG 43  47  47  ARG ARG D . n 
D 4 44  LYS 44  48  48  LYS LYS D . n 
D 4 45  GLU 45  49  49  GLU GLU D . n 
D 4 46  PRO 46  50  50  PRO PRO D . n 
D 4 47  LYS 47  51  51  LYS LYS D . n 
D 4 48  LEU 48  52  52  LEU LEU D . n 
D 4 49  LEU 49  53  53  LEU LEU D . n 
D 4 50  MET 50  54  54  MET MET D . n 
D 4 51  SER 51  55  55  SER SER D . n 
D 4 52  VAL 52  56  56  VAL VAL D . n 
D 4 53  TYR 53  57  57  TYR TYR D . n 
D 4 54  SER 54  58  58  SER SER D . n 
D 4 55  SER 55  63  63  SER SER D . n 
D 4 56  GLY 56  64  64  GLY GLY D . n 
D 4 57  ASN 57  65  65  ASN ASN D . n 
D 4 58  GLU 58  67  67  GLU GLU D . n 
D 4 59  ASP 59  68  68  ASP ASP D . n 
D 4 60  GLY 60  74  74  GLY GLY D . n 
D 4 61  ARG 61  75  75  ARG ARG D . n 
D 4 62  PHE 62  76  76  PHE PHE D . n 
D 4 63  THR 63  77  77  THR THR D . n 
D 4 64  ALA 64  78  78  ALA ALA D . n 
D 4 65  GLN 65  79  79  GLN GLN D . n 
D 4 66  LEU 66  80  80  LEU LEU D . n 
D 4 67  ASN 67  81  81  ASN ASN D . n 
D 4 68  ARG 68  82  82  ARG ARG D . n 
D 4 69  ALA 69  83  83  ALA ALA D . n 
D 4 70  SER 70  84  84  SER SER D . n 
D 4 71  GLN 71  85  85  GLN GLN D . n 
D 4 72  TYR 72  86  86  TYR TYR D . n 
D 4 73  ILE 73  87  87  ILE ILE D . n 
D 4 74  SER 74  88  88  SER SER D . n 
D 4 75  LEU 75  89  89  LEU LEU D . n 
D 4 76  LEU 76  90  90  LEU LEU D . n 
D 4 77  ILE 77  91  91  ILE ILE D . n 
D 4 78  ARG 78  92  92  ARG ARG D . n 
D 4 79  ASP 79  93  93  ASP ASP D . n 
D 4 80  SER 80  94  94  SER SER D . n 
D 4 81  LYS 81  95  95  LYS LYS D . n 
D 4 82  LEU 82  96  96  LEU LEU D . n 
D 4 83  SER 83  97  97  SER SER D . n 
D 4 84  ASP 84  98  98  ASP ASP D . n 
D 4 85  SER 85  99  99  SER SER D . n 
D 4 86  ALA 86  100 100 ALA ALA D . n 
D 4 87  THR 87  101 101 THR THR D . n 
D 4 88  TYR 88  102 102 TYR TYR D . n 
D 4 89  LEU 89  103 103 LEU LEU D . n 
D 4 90  CYS 90  104 104 CYS CYS D . n 
D 4 91  VAL 91  105 105 VAL VAL D . n 
D 4 92  VAL 92  106 106 VAL VAL D . n 
D 4 93  MET 93  107 107 MET MET D . n 
D 4 94  GLY 94  108 108 GLY GLY D . n 
D 4 95  PHE 95  109 109 PHE PHE D . n 
D 4 96  GLN 96  110 110 GLN GLN D . n 
D 4 97  LYS 97  111 111 LYS LYS D . n 
D 4 98  LEU 98  112 112 LEU LEU D . n 
D 4 99  VAL 99  113 113 VAL VAL D . n 
D 4 100 PHE 100 114 114 PHE PHE D . n 
D 4 101 GLY 101 115 115 GLY GLY D . n 
D 4 102 THR 102 116 116 THR THR D . n 
D 4 103 GLY 103 117 117 GLY GLY D . n 
D 4 104 THR 104 118 118 THR THR D . n 
D 4 105 ARG 105 119 119 ARG ARG D . n 
D 4 106 LEU 106 120 120 LEU LEU D . n 
D 4 107 LEU 107 121 121 LEU LEU D . n 
D 4 108 VAL 108 122 122 VAL VAL D . n 
D 4 109 SER 109 123 123 SER SER D . n 
D 4 110 PRO 110 124 124 PRO PRO D . n 
D 4 111 ASN 111 125 125 ASN ASN D . n 
D 4 112 ILE 112 126 126 ILE ILE D . n 
D 4 113 GLN 113 127 127 GLN GLN D . n 
D 4 114 ASN 114 128 128 ASN ASN D . n 
D 4 115 PRO 115 129 129 PRO PRO D . n 
D 4 116 ASP 116 130 130 ASP ASP D . n 
D 4 117 PRO 117 131 131 PRO PRO D . n 
D 4 118 ALA 118 132 132 ALA ALA D . n 
D 4 119 VAL 119 133 133 VAL VAL D . n 
D 4 120 TYR 120 134 134 TYR TYR D . n 
D 4 121 GLN 121 135 135 GLN GLN D . n 
D 4 122 LEU 122 136 136 LEU LEU D . n 
D 4 123 ARG 123 137 137 ARG ARG D . n 
D 4 124 ASP 124 138 138 ASP ASP D . n 
D 4 125 SER 125 139 139 SER SER D . n 
D 4 126 LYS 126 140 140 LYS LYS D . n 
D 4 127 SER 127 141 141 SER SER D . n 
D 4 128 SER 128 142 142 SER SER D . n 
D 4 129 ASP 129 143 143 ASP ASP D . n 
D 4 130 LYS 130 144 144 LYS LYS D . n 
D 4 131 SER 131 145 145 SER SER D . n 
D 4 132 VAL 132 146 146 VAL VAL D . n 
D 4 133 CYS 133 147 147 CYS CYS D . n 
D 4 134 LEU 134 148 148 LEU LEU D . n 
D 4 135 PHE 135 149 149 PHE PHE D . n 
D 4 136 THR 136 150 150 THR THR D . n 
D 4 137 ASP 137 151 151 ASP ASP D . n 
D 4 138 PHE 138 152 152 PHE PHE D . n 
D 4 139 ASP 139 153 153 ASP ASP D . n 
D 4 140 SER 140 154 154 SER SER D . n 
D 4 141 GLN 141 155 155 GLN GLN D . n 
D 4 142 THR 142 156 156 THR THR D . n 
D 4 143 ASN 143 157 157 ASN ASN D . n 
D 4 144 VAL 144 158 158 VAL VAL D . n 
D 4 145 SER 145 159 159 SER SER D . n 
D 4 146 GLN 146 160 160 GLN GLN D . n 
D 4 147 SER 147 161 161 SER SER D . n 
D 4 148 LYS 148 162 162 LYS LYS D . n 
D 4 149 ASP 149 163 163 ASP ASP D . n 
D 4 150 SER 150 164 164 SER SER D . n 
D 4 151 ASP 151 165 165 ASP ASP D . n 
D 4 152 VAL 152 166 166 VAL VAL D . n 
D 4 153 TYR 153 167 167 TYR TYR D . n 
D 4 154 ILE 154 168 168 ILE ILE D . n 
D 4 155 THR 155 169 169 THR THR D . n 
D 4 156 ASP 156 170 170 ASP ASP D . n 
D 4 157 LYS 157 171 171 LYS LYS D . n 
D 4 158 CYS 158 172 172 CYS CYS D . n 
D 4 159 VAL 159 173 173 VAL VAL D . n 
D 4 160 LEU 160 174 174 LEU LEU D . n 
D 4 161 ASP 161 175 175 ASP ASP D . n 
D 4 162 MET 162 176 176 MET MET D . n 
D 4 163 ARG 163 177 177 ARG ARG D . n 
D 4 164 SER 164 178 178 SER SER D . n 
D 4 165 MET 165 179 179 MET MET D . n 
D 4 166 ASP 166 180 180 ASP ASP D . n 
D 4 167 PHE 167 181 181 PHE PHE D . n 
D 4 168 LYS 168 182 182 LYS LYS D . n 
D 4 169 SER 169 183 183 SER SER D . n 
D 4 170 ASN 170 184 184 ASN ASN D . n 
D 4 171 SER 171 185 185 SER SER D . n 
D 4 172 ALA 172 186 186 ALA ALA D . n 
D 4 173 VAL 173 187 187 VAL VAL D . n 
D 4 174 ALA 174 188 188 ALA ALA D . n 
D 4 175 TRP 175 189 189 TRP TRP D . n 
D 4 176 SER 176 190 190 SER SER D . n 
D 4 177 ASN 177 191 191 ASN ASN D . n 
D 4 178 LYS 178 192 192 LYS LYS D . n 
D 4 179 SER 179 193 193 SER SER D . n 
D 4 180 ASP 180 194 194 ASP ASP D . n 
D 4 181 PHE 181 195 195 PHE PHE D . n 
D 4 182 ALA 182 196 196 ALA ALA D . n 
D 4 183 CYS 183 197 197 CYS CYS D . n 
D 4 184 ALA 184 198 198 ALA ALA D . n 
D 4 185 ASN 185 199 199 ASN ASN D . n 
D 4 186 ALA 186 200 200 ALA ALA D . n 
D 4 187 PHE 187 201 201 PHE PHE D . n 
D 4 188 ASN 188 202 202 ASN ASN D . n 
D 4 189 ASN 189 203 203 ASN ASN D . n 
D 4 190 SER 190 204 204 SER SER D . n 
D 4 191 ILE 191 205 205 ILE ILE D . n 
D 4 192 ILE 192 206 206 ILE ILE D . n 
D 4 193 PRO 193 207 207 PRO PRO D . n 
D 4 194 GLU 194 208 208 GLU GLU D . n 
D 4 195 ASP 195 209 209 ASP ASP D . n 
D 4 196 THR 196 210 210 THR THR D . n 
D 4 197 PHE 197 211 211 PHE PHE D . n 
D 4 198 PHE 198 212 212 PHE PHE D . n 
D 4 199 PRO 199 213 213 PRO PRO D . n 
D 4 200 SER 200 214 214 SER SER D . n 
D 4 201 PRO 201 215 215 PRO PRO D . n 
D 4 202 GLU 202 216 ?   ?   ?   D . n 
D 4 203 SER 203 217 ?   ?   ?   D . n 
D 4 204 SER 204 218 ?   ?   ?   D . n 
E 5 1   MET 1   2   ?   ?   ?   E . n 
E 5 2   GLY 2   3   3   GLY GLY E . n 
E 5 3   VAL 3   4   4   VAL VAL E . n 
E 5 4   THR 4   5   5   THR THR E . n 
E 5 5   GLN 5   6   6   GLN GLN E . n 
E 5 6   THR 6   7   7   THR THR E . n 
E 5 7   PRO 7   8   8   PRO PRO E . n 
E 5 8   ARG 8   9   9   ARG ARG E . n 
E 5 9   TYR 9   10  10  TYR TYR E . n 
E 5 10  LEU 10  11  11  LEU LEU E . n 
E 5 11  ILE 11  12  12  ILE ILE E . n 
E 5 12  LYS 12  13  13  LYS LYS E . n 
E 5 13  THR 13  14  14  THR THR E . n 
E 5 14  ARG 14  15  15  ARG ARG E . n 
E 5 15  GLY 15  16  16  GLY GLY E . n 
E 5 16  GLN 16  17  17  GLN GLN E . n 
E 5 17  GLN 17  18  18  GLN GLN E . n 
E 5 18  VAL 18  19  19  VAL VAL E . n 
E 5 19  THR 19  20  20  THR THR E . n 
E 5 20  LEU 20  21  21  LEU LEU E . n 
E 5 21  SER 21  22  22  SER SER E . n 
E 5 22  CYS 22  23  23  CYS CYS E . n 
E 5 23  SER 23  24  24  SER SER E . n 
E 5 24  PRO 24  25  25  PRO PRO E . n 
E 5 25  ILE 25  26  26  ILE ILE E . n 
E 5 26  SER 26  27  27  SER SER E . n 
E 5 27  GLY 27  28  28  GLY GLY E . n 
E 5 28  HIS 28  29  29  HIS HIS E . n 
E 5 29  ARG 29  37  37  ARG ARG E . n 
E 5 30  SER 30  38  38  SER SER E . n 
E 5 31  VAL 31  39  39  VAL VAL E . n 
E 5 32  SER 32  40  40  SER SER E . n 
E 5 33  TRP 33  41  41  TRP TRP E . n 
E 5 34  TYR 34  42  42  TYR TYR E . n 
E 5 35  GLN 35  43  43  GLN GLN E . n 
E 5 36  GLN 36  44  44  GLN GLN E . n 
E 5 37  THR 37  45  45  THR THR E . n 
E 5 38  PRO 38  46  46  PRO PRO E . n 
E 5 39  GLY 39  47  47  GLY GLY E . n 
E 5 40  GLN 40  48  48  GLN GLN E . n 
E 5 41  GLY 41  49  49  GLY GLY E . n 
E 5 42  LEU 42  50  50  LEU LEU E . n 
E 5 43  GLN 43  51  51  GLN GLN E . n 
E 5 44  PHE 44  52  52  PHE PHE E . n 
E 5 45  LEU 45  53  53  LEU LEU E . n 
E 5 46  PHE 46  54  54  PHE PHE E . n 
E 5 47  GLU 47  55  55  GLU GLU E . n 
E 5 48  TYR 48  56  56  TYR TYR E . n 
E 5 49  PHE 49  57  57  PHE PHE E . n 
E 5 50  SER 50  58  58  SER SER E . n 
E 5 51  GLU 51  63  63  GLU GLU E . n 
E 5 52  THR 52  64  64  THR THR E . n 
E 5 53  GLN 53  65  65  GLN GLN E . n 
E 5 54  ARG 54  66  66  ARG ARG E . n 
E 5 55  ASN 55  67  67  ASN ASN E . n 
E 5 56  LYS 56  68  68  LYS LYS E . n 
E 5 57  GLY 57  69  69  GLY GLY E . n 
E 5 58  ASN 58  70  70  ASN ASN E . n 
E 5 59  PHE 59  71  71  PHE PHE E . n 
E 5 60  PRO 60  72  72  PRO PRO E . n 
E 5 61  GLY 61  74  74  GLY GLY E . n 
E 5 62  ARG 62  75  75  ARG ARG E . n 
E 5 63  PHE 63  76  76  PHE PHE E . n 
E 5 64  SER 64  77  77  SER SER E . n 
E 5 65  GLY 65  78  78  GLY GLY E . n 
E 5 66  ARG 66  79  79  ARG ARG E . n 
E 5 67  GLN 67  80  80  GLN GLN E . n 
E 5 68  PHE 68  81  81  PHE PHE E . n 
E 5 69  SER 69  83  83  SER SER E . n 
E 5 70  ASN 70  84  84  ASN ASN E . n 
E 5 71  SER 71  85  85  SER SER E . n 
E 5 72  ARG 72  86  86  ARG ARG E . n 
E 5 73  SER 73  87  87  SER SER E . n 
E 5 74  GLU 74  88  88  GLU GLU E . n 
E 5 75  MET 75  89  89  MET MET E . n 
E 5 76  ASN 76  90  90  ASN ASN E . n 
E 5 77  VAL 77  91  91  VAL VAL E . n 
E 5 78  SER 78  92  92  SER SER E . n 
E 5 79  THR 79  93  93  THR THR E . n 
E 5 80  LEU 80  94  94  LEU LEU E . n 
E 5 81  GLU 81  95  95  GLU GLU E . n 
E 5 82  LEU 82  96  96  LEU LEU E . n 
E 5 83  GLY 83  97  97  GLY GLY E . n 
E 5 84  ASP 84  98  98  ASP ASP E . n 
E 5 85  SER 85  99  99  SER SER E . n 
E 5 86  ALA 86  100 100 ALA ALA E . n 
E 5 87  LEU 87  101 101 LEU LEU E . n 
E 5 88  TYR 88  102 102 TYR TYR E . n 
E 5 89  LEU 89  103 103 LEU LEU E . n 
E 5 90  CYS 90  104 104 CYS CYS E . n 
E 5 91  ALA 91  105 105 ALA ALA E . n 
E 5 92  SER 92  106 106 SER SER E . n 
E 5 93  SER 93  107 107 SER SER E . n 
E 5 94  LEU 94  108 108 LEU LEU E . n 
E 5 95  ARG 95  109 109 ARG ARG E . n 
E 5 96  ALA 96  110 110 ALA ALA E . n 
E 5 97  GLU 97  111 111 GLU GLU E . n 
E 5 98  SER 98  112 112 SER SER E . n 
E 5 99  GLY 99  113 113 GLY GLY E . n 
E 5 100 GLU 100 114 114 GLU GLU E . n 
E 5 101 LEU 101 115 115 LEU LEU E . n 
E 5 102 PHE 102 116 116 PHE PHE E . n 
E 5 103 PHE 103 117 117 PHE PHE E . n 
E 5 104 GLY 104 118 118 GLY GLY E . n 
E 5 105 GLU 105 119 119 GLU GLU E . n 
E 5 106 GLY 106 120 120 GLY GLY E . n 
E 5 107 SER 107 121 121 SER SER E . n 
E 5 108 ARG 108 122 122 ARG ARG E . n 
E 5 109 LEU 109 123 123 LEU LEU E . n 
E 5 110 THR 110 124 124 THR THR E . n 
E 5 111 VAL 111 125 125 VAL VAL E . n 
E 5 112 LEU 112 126 126 LEU LEU E . n 
E 5 113 GLU 113 127 127 GLU GLU E . n 
E 5 114 ASP 114 128 128 ASP ASP E . n 
E 5 115 LEU 115 129 129 LEU LEU E . n 
E 5 116 ASN 116 130 130 ASN ASN E . n 
E 5 117 LYS 117 131 131 LYS LYS E . n 
E 5 118 VAL 118 132 132 VAL VAL E . n 
E 5 119 PHE 119 133 133 PHE PHE E . n 
E 5 120 PRO 120 134 134 PRO PRO E . n 
E 5 121 PRO 121 135 135 PRO PRO E . n 
E 5 122 GLU 122 136 136 GLU GLU E . n 
E 5 123 VAL 123 137 137 VAL VAL E . n 
E 5 124 ALA 124 138 138 ALA ALA E . n 
E 5 125 VAL 125 139 139 VAL VAL E . n 
E 5 126 PHE 126 140 140 PHE PHE E . n 
E 5 127 GLU 127 141 141 GLU GLU E . n 
E 5 128 PRO 128 142 142 PRO PRO E . n 
E 5 129 SER 129 143 143 SER SER E . n 
E 5 130 GLU 130 144 144 GLU GLU E . n 
E 5 131 ALA 131 145 145 ALA ALA E . n 
E 5 132 GLU 132 146 146 GLU GLU E . n 
E 5 133 ILE 133 147 147 ILE ILE E . n 
E 5 134 SER 134 148 148 SER SER E . n 
E 5 135 HIS 135 149 149 HIS HIS E . n 
E 5 136 THR 136 150 150 THR THR E . n 
E 5 137 GLN 137 151 151 GLN GLN E . n 
E 5 138 LYS 138 152 152 LYS LYS E . n 
E 5 139 ALA 139 153 153 ALA ALA E . n 
E 5 140 THR 140 154 154 THR THR E . n 
E 5 141 LEU 141 155 155 LEU LEU E . n 
E 5 142 VAL 142 156 156 VAL VAL E . n 
E 5 143 CYS 143 157 157 CYS CYS E . n 
E 5 144 LEU 144 158 158 LEU LEU E . n 
E 5 145 ALA 145 159 159 ALA ALA E . n 
E 5 146 THR 146 160 160 THR THR E . n 
E 5 147 GLY 147 161 161 GLY GLY E . n 
E 5 148 PHE 148 162 162 PHE PHE E . n 
E 5 149 PHE 149 163 163 PHE PHE E . n 
E 5 150 PRO 150 164 164 PRO PRO E . n 
E 5 151 ASP 151 165 165 ASP ASP E . n 
E 5 152 HIS 152 166 166 HIS HIS E . n 
E 5 153 VAL 153 167 167 VAL VAL E . n 
E 5 154 GLU 154 168 168 GLU GLU E . n 
E 5 155 LEU 155 169 169 LEU LEU E . n 
E 5 156 SER 156 170 170 SER SER E . n 
E 5 157 TRP 157 171 171 TRP TRP E . n 
E 5 158 TRP 158 172 172 TRP TRP E . n 
E 5 159 VAL 159 173 173 VAL VAL E . n 
E 5 160 ASN 160 174 174 ASN ASN E . n 
E 5 161 GLY 161 175 175 GLY GLY E . n 
E 5 162 LYS 162 176 176 LYS LYS E . n 
E 5 163 GLU 163 177 177 GLU GLU E . n 
E 5 164 VAL 164 178 178 VAL VAL E . n 
E 5 165 HIS 165 179 179 HIS HIS E . n 
E 5 166 SER 166 180 180 SER SER E . n 
E 5 167 GLY 167 181 181 GLY GLY E . n 
E 5 168 VAL 168 182 182 VAL VAL E . n 
E 5 169 CYS 169 183 183 CYS CYS E . n 
E 5 170 THR 170 184 184 THR THR E . n 
E 5 171 ASP 171 185 185 ASP ASP E . n 
E 5 172 PRO 172 186 186 PRO PRO E . n 
E 5 173 GLN 173 187 187 GLN GLN E . n 
E 5 174 PRO 174 188 188 PRO PRO E . n 
E 5 175 LEU 175 189 189 LEU LEU E . n 
E 5 176 LYS 176 190 190 LYS LYS E . n 
E 5 177 GLU 177 191 191 GLU GLU E . n 
E 5 178 GLN 178 192 192 GLN GLN E . n 
E 5 179 PRO 179 193 193 PRO PRO E . n 
E 5 180 ALA 180 194 194 ALA ALA E . n 
E 5 181 LEU 181 195 195 LEU LEU E . n 
E 5 182 ASN 182 196 196 ASN ASN E . n 
E 5 183 ASP 183 197 197 ASP ASP E . n 
E 5 184 SER 184 198 198 SER SER E . n 
E 5 185 ARG 185 199 199 ARG ARG E . n 
E 5 186 TYR 186 200 200 TYR TYR E . n 
E 5 187 ALA 187 201 201 ALA ALA E . n 
E 5 188 LEU 188 202 202 LEU LEU E . n 
E 5 189 SER 189 203 203 SER SER E . n 
E 5 190 SER 190 204 204 SER SER E . n 
E 5 191 ARG 191 205 205 ARG ARG E . n 
E 5 192 LEU 192 206 206 LEU LEU E . n 
E 5 193 ARG 193 207 207 ARG ARG E . n 
E 5 194 VAL 194 208 208 VAL VAL E . n 
E 5 195 SER 195 209 209 SER SER E . n 
E 5 196 ALA 196 210 210 ALA ALA E . n 
E 5 197 THR 197 211 211 THR THR E . n 
E 5 198 PHE 198 212 212 PHE PHE E . n 
E 5 199 TRP 199 213 213 TRP TRP E . n 
E 5 200 GLN 200 214 214 GLN GLN E . n 
E 5 201 ASN 201 215 215 ASN ASN E . n 
E 5 202 PRO 202 216 216 PRO PRO E . n 
E 5 203 ARG 203 217 217 ARG ARG E . n 
E 5 204 ASN 204 218 218 ASN ASN E . n 
E 5 205 HIS 205 219 219 HIS HIS E . n 
E 5 206 PHE 206 220 220 PHE PHE E . n 
E 5 207 ARG 207 221 221 ARG ARG E . n 
E 5 208 CYS 208 222 222 CYS CYS E . n 
E 5 209 GLN 209 223 223 GLN GLN E . n 
E 5 210 VAL 210 224 224 VAL VAL E . n 
E 5 211 GLN 211 225 225 GLN GLN E . n 
E 5 212 PHE 212 226 226 PHE PHE E . n 
E 5 213 TYR 213 227 227 TYR TYR E . n 
E 5 214 GLY 214 228 228 GLY GLY E . n 
E 5 215 LEU 215 229 229 LEU LEU E . n 
E 5 216 SER 216 230 230 SER SER E . n 
E 5 217 GLU 217 231 231 GLU GLU E . n 
E 5 218 ASN 218 232 232 ASN ASN E . n 
E 5 219 ASP 219 233 233 ASP ASP E . n 
E 5 220 GLU 220 234 234 GLU GLU E . n 
E 5 221 TRP 221 235 235 TRP TRP E . n 
E 5 222 THR 222 236 236 THR THR E . n 
E 5 223 GLN 223 237 237 GLN GLN E . n 
E 5 224 ASP 224 238 238 ASP ASP E . n 
E 5 225 ARG 225 239 239 ARG ARG E . n 
E 5 226 ALA 226 240 240 ALA ALA E . n 
E 5 227 LYS 227 241 241 LYS LYS E . n 
E 5 228 PRO 228 242 242 PRO PRO E . n 
E 5 229 VAL 229 243 243 VAL VAL E . n 
E 5 230 THR 230 244 244 THR THR E . n 
E 5 231 GLN 231 245 245 GLN GLN E . n 
E 5 232 ILE 232 246 246 ILE ILE E . n 
E 5 233 VAL 233 247 247 VAL VAL E . n 
E 5 234 SER 234 248 248 SER SER E . n 
E 5 235 ALA 235 249 249 ALA ALA E . n 
E 5 236 GLU 236 250 250 GLU GLU E . n 
E 5 237 ALA 237 251 251 ALA ALA E . n 
E 5 238 TRP 238 252 252 TRP TRP E . n 
E 5 239 GLY 239 253 253 GLY GLY E . n 
E 5 240 ARG 240 254 254 ARG ARG E . n 
E 5 241 ALA 241 255 255 ALA ALA E . n 
E 5 242 ASP 242 256 256 ASP ASP E . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
F 6 NAG 1 F NAG 1 A NAG 182 n 
F 6 NAG 2 F NAG 2 A NAG 183 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 7  GOL 1   201 184 GOL GOL A . 
H 8  NAG 1   201 192 NAG NAG B . 
I 9  ACT 1   101 101 ACT ACT C . 
J 9  ACT 1   301 301 ACT ACT D . 
K 9  ACT 1   301 302 ACT ACT E . 
L 7  GOL 1   302 303 GOL GOL E . 
M 10 HOH 1   301 151 HOH HOH A . 
M 10 HOH 2   302 22  HOH HOH A . 
M 10 HOH 3   303 71  HOH HOH A . 
M 10 HOH 4   304 284 HOH HOH A . 
M 10 HOH 5   305 318 HOH HOH A . 
M 10 HOH 6   306 125 HOH HOH A . 
M 10 HOH 7   307 520 HOH HOH A . 
M 10 HOH 8   308 486 HOH HOH A . 
M 10 HOH 9   309 120 HOH HOH A . 
M 10 HOH 10  310 59  HOH HOH A . 
M 10 HOH 11  311 5   HOH HOH A . 
M 10 HOH 12  312 158 HOH HOH A . 
M 10 HOH 13  313 199 HOH HOH A . 
M 10 HOH 14  314 212 HOH HOH A . 
M 10 HOH 15  315 74  HOH HOH A . 
M 10 HOH 16  316 101 HOH HOH A . 
M 10 HOH 17  317 111 HOH HOH A . 
M 10 HOH 18  318 78  HOH HOH A . 
M 10 HOH 19  319 118 HOH HOH A . 
M 10 HOH 20  320 381 HOH HOH A . 
M 10 HOH 21  321 138 HOH HOH A . 
M 10 HOH 22  322 197 HOH HOH A . 
M 10 HOH 23  323 40  HOH HOH A . 
M 10 HOH 24  324 20  HOH HOH A . 
M 10 HOH 25  325 291 HOH HOH A . 
M 10 HOH 26  326 259 HOH HOH A . 
M 10 HOH 27  327 103 HOH HOH A . 
M 10 HOH 28  328 117 HOH HOH A . 
M 10 HOH 29  329 18  HOH HOH A . 
M 10 HOH 30  330 51  HOH HOH A . 
M 10 HOH 31  331 205 HOH HOH A . 
M 10 HOH 32  332 430 HOH HOH A . 
M 10 HOH 33  333 41  HOH HOH A . 
M 10 HOH 34  334 379 HOH HOH A . 
M 10 HOH 35  335 348 HOH HOH A . 
M 10 HOH 36  336 67  HOH HOH A . 
M 10 HOH 37  337 63  HOH HOH A . 
M 10 HOH 38  338 43  HOH HOH A . 
M 10 HOH 39  339 176 HOH HOH A . 
M 10 HOH 40  340 95  HOH HOH A . 
M 10 HOH 41  341 189 HOH HOH A . 
M 10 HOH 42  342 436 HOH HOH A . 
M 10 HOH 43  343 164 HOH HOH A . 
M 10 HOH 44  344 86  HOH HOH A . 
M 10 HOH 45  345 237 HOH HOH A . 
M 10 HOH 46  346 282 HOH HOH A . 
M 10 HOH 47  347 6   HOH HOH A . 
M 10 HOH 48  348 245 HOH HOH A . 
M 10 HOH 49  349 137 HOH HOH A . 
M 10 HOH 50  350 81  HOH HOH A . 
M 10 HOH 51  351 57  HOH HOH A . 
M 10 HOH 52  352 126 HOH HOH A . 
M 10 HOH 53  353 244 HOH HOH A . 
M 10 HOH 54  354 278 HOH HOH A . 
M 10 HOH 55  355 390 HOH HOH A . 
M 10 HOH 56  356 286 HOH HOH A . 
M 10 HOH 57  357 96  HOH HOH A . 
M 10 HOH 58  358 419 HOH HOH A . 
M 10 HOH 59  359 144 HOH HOH A . 
M 10 HOH 60  360 160 HOH HOH A . 
M 10 HOH 61  361 204 HOH HOH A . 
M 10 HOH 62  362 208 HOH HOH A . 
M 10 HOH 63  363 185 HOH HOH A . 
M 10 HOH 64  364 388 HOH HOH A . 
M 10 HOH 65  365 236 HOH HOH A . 
M 10 HOH 66  366 112 HOH HOH A . 
M 10 HOH 67  367 382 HOH HOH A . 
M 10 HOH 68  368 433 HOH HOH A . 
M 10 HOH 69  369 279 HOH HOH A . 
M 10 HOH 70  370 206 HOH HOH A . 
M 10 HOH 71  371 400 HOH HOH A . 
M 10 HOH 72  372 297 HOH HOH A . 
M 10 HOH 73  373 481 HOH HOH A . 
M 10 HOH 74  374 399 HOH HOH A . 
M 10 HOH 75  375 298 HOH HOH A . 
M 10 HOH 76  376 154 HOH HOH A . 
M 10 HOH 77  377 336 HOH HOH A . 
M 10 HOH 78  378 415 HOH HOH A . 
M 10 HOH 79  379 173 HOH HOH A . 
M 10 HOH 80  380 222 HOH HOH A . 
M 10 HOH 81  381 308 HOH HOH A . 
M 10 HOH 82  382 141 HOH HOH A . 
M 10 HOH 83  383 200 HOH HOH A . 
M 10 HOH 84  384 385 HOH HOH A . 
M 10 HOH 85  385 502 HOH HOH A . 
M 10 HOH 86  386 440 HOH HOH A . 
M 10 HOH 87  387 242 HOH HOH A . 
M 10 HOH 88  388 484 HOH HOH A . 
M 10 HOH 89  389 476 HOH HOH A . 
M 10 HOH 90  390 253 HOH HOH A . 
M 10 HOH 91  391 231 HOH HOH A . 
M 10 HOH 92  392 374 HOH HOH A . 
M 10 HOH 93  393 479 HOH HOH A . 
M 10 HOH 94  394 532 HOH HOH A . 
M 10 HOH 95  395 210 HOH HOH A . 
M 10 HOH 96  396 529 HOH HOH A . 
M 10 HOH 97  397 355 HOH HOH A . 
M 10 HOH 98  398 477 HOH HOH A . 
M 10 HOH 99  399 528 HOH HOH A . 
M 10 HOH 100 400 427 HOH HOH A . 
M 10 HOH 101 401 438 HOH HOH A . 
M 10 HOH 102 402 209 HOH HOH A . 
M 10 HOH 103 403 530 HOH HOH A . 
M 10 HOH 104 404 482 HOH HOH A . 
M 10 HOH 105 405 527 HOH HOH A . 
M 10 HOH 106 406 202 HOH HOH A . 
M 10 HOH 107 407 410 HOH HOH A . 
M 10 HOH 108 408 539 HOH HOH A . 
M 10 HOH 109 409 354 HOH HOH A . 
M 10 HOH 110 410 409 HOH HOH A . 
M 10 HOH 111 411 269 HOH HOH A . 
M 10 HOH 112 412 483 HOH HOH A . 
M 10 HOH 113 413 325 HOH HOH A . 
M 10 HOH 114 414 437 HOH HOH A . 
M 10 HOH 115 415 480 HOH HOH A . 
M 10 HOH 116 416 429 HOH HOH A . 
M 10 HOH 117 417 489 HOH HOH A . 
M 10 HOH 118 418 311 HOH HOH A . 
M 10 HOH 119 419 247 HOH HOH A . 
N 10 HOH 1   301 414 HOH HOH B . 
N 10 HOH 2   302 122 HOH HOH B . 
N 10 HOH 3   303 53  HOH HOH B . 
N 10 HOH 4   304 540 HOH HOH B . 
N 10 HOH 5   305 90  HOH HOH B . 
N 10 HOH 6   306 220 HOH HOH B . 
N 10 HOH 7   307 66  HOH HOH B . 
N 10 HOH 8   308 56  HOH HOH B . 
N 10 HOH 9   309 142 HOH HOH B . 
N 10 HOH 10  310 170 HOH HOH B . 
N 10 HOH 11  311 11  HOH HOH B . 
N 10 HOH 12  312 216 HOH HOH B . 
N 10 HOH 13  313 132 HOH HOH B . 
N 10 HOH 14  314 426 HOH HOH B . 
N 10 HOH 15  315 341 HOH HOH B . 
N 10 HOH 16  316 4   HOH HOH B . 
N 10 HOH 17  317 243 HOH HOH B . 
N 10 HOH 18  318 188 HOH HOH B . 
N 10 HOH 19  319 352 HOH HOH B . 
N 10 HOH 20  320 349 HOH HOH B . 
N 10 HOH 21  321 192 HOH HOH B . 
N 10 HOH 22  322 72  HOH HOH B . 
N 10 HOH 23  323 340 HOH HOH B . 
N 10 HOH 24  324 21  HOH HOH B . 
N 10 HOH 25  325 168 HOH HOH B . 
N 10 HOH 26  326 108 HOH HOH B . 
N 10 HOH 27  327 165 HOH HOH B . 
N 10 HOH 28  328 39  HOH HOH B . 
N 10 HOH 29  329 89  HOH HOH B . 
N 10 HOH 30  330 364 HOH HOH B . 
N 10 HOH 31  331 54  HOH HOH B . 
N 10 HOH 32  332 523 HOH HOH B . 
N 10 HOH 33  333 171 HOH HOH B . 
N 10 HOH 34  334 45  HOH HOH B . 
N 10 HOH 35  335 166 HOH HOH B . 
N 10 HOH 36  336 17  HOH HOH B . 
N 10 HOH 37  337 343 HOH HOH B . 
N 10 HOH 38  338 211 HOH HOH B . 
N 10 HOH 39  339 183 HOH HOH B . 
N 10 HOH 40  340 323 HOH HOH B . 
N 10 HOH 41  341 405 HOH HOH B . 
N 10 HOH 42  342 281 HOH HOH B . 
N 10 HOH 43  343 294 HOH HOH B . 
N 10 HOH 44  344 61  HOH HOH B . 
N 10 HOH 45  345 320 HOH HOH B . 
N 10 HOH 46  346 149 HOH HOH B . 
N 10 HOH 47  347 304 HOH HOH B . 
N 10 HOH 48  348 338 HOH HOH B . 
N 10 HOH 49  349 504 HOH HOH B . 
N 10 HOH 50  350 544 HOH HOH B . 
N 10 HOH 51  351 48  HOH HOH B . 
N 10 HOH 52  352 299 HOH HOH B . 
N 10 HOH 53  353 295 HOH HOH B . 
N 10 HOH 54  354 487 HOH HOH B . 
N 10 HOH 55  355 181 HOH HOH B . 
N 10 HOH 56  356 439 HOH HOH B . 
N 10 HOH 57  357 272 HOH HOH B . 
N 10 HOH 58  358 519 HOH HOH B . 
N 10 HOH 59  359 447 HOH HOH B . 
N 10 HOH 60  360 526 HOH HOH B . 
N 10 HOH 61  361 412 HOH HOH B . 
N 10 HOH 62  362 123 HOH HOH B . 
N 10 HOH 63  363 224 HOH HOH B . 
N 10 HOH 64  364 44  HOH HOH B . 
N 10 HOH 65  365 444 HOH HOH B . 
N 10 HOH 66  366 121 HOH HOH B . 
N 10 HOH 67  367 274 HOH HOH B . 
N 10 HOH 68  368 445 HOH HOH B . 
N 10 HOH 69  369 357 HOH HOH B . 
N 10 HOH 70  370 503 HOH HOH B . 
N 10 HOH 71  371 443 HOH HOH B . 
N 10 HOH 72  372 280 HOH HOH B . 
N 10 HOH 73  373 233 HOH HOH B . 
N 10 HOH 74  374 285 HOH HOH B . 
N 10 HOH 75  375 442 HOH HOH B . 
N 10 HOH 76  376 239 HOH HOH B . 
N 10 HOH 77  377 524 HOH HOH B . 
N 10 HOH 78  378 321 HOH HOH B . 
N 10 HOH 79  379 332 HOH HOH B . 
N 10 HOH 80  380 425 HOH HOH B . 
N 10 HOH 81  381 314 HOH HOH B . 
N 10 HOH 82  382 372 HOH HOH B . 
N 10 HOH 83  383 525 HOH HOH B . 
N 10 HOH 84  384 500 HOH HOH B . 
N 10 HOH 85  385 448 HOH HOH B . 
N 10 HOH 86  386 522 HOH HOH B . 
N 10 HOH 87  387 542 HOH HOH B . 
N 10 HOH 88  388 441 HOH HOH B . 
N 10 HOH 89  389 535 HOH HOH B . 
N 10 HOH 90  390 98  HOH HOH B . 
N 10 HOH 91  391 361 HOH HOH B . 
N 10 HOH 92  392 521 HOH HOH B . 
N 10 HOH 93  393 485 HOH HOH B . 
N 10 HOH 94  394 411 HOH HOH B . 
N 10 HOH 95  395 517 HOH HOH B . 
N 10 HOH 96  396 490 HOH HOH B . 
N 10 HOH 97  397 478 HOH HOH B . 
O 10 HOH 1   501 501 HOH HOH C . 
O 10 HOH 2   502 435 HOH HOH C . 
O 10 HOH 3   503 115 HOH HOH C . 
O 10 HOH 4   504 273 HOH HOH C . 
P 10 HOH 1   401 317 HOH HOH D . 
P 10 HOH 2   402 346 HOH HOH D . 
P 10 HOH 3   403 92  HOH HOH D . 
P 10 HOH 4   404 162 HOH HOH D . 
P 10 HOH 5   405 135 HOH HOH D . 
P 10 HOH 6   406 432 HOH HOH D . 
P 10 HOH 7   407 384 HOH HOH D . 
P 10 HOH 8   408 306 HOH HOH D . 
P 10 HOH 9   409 428 HOH HOH D . 
P 10 HOH 10  410 100 HOH HOH D . 
P 10 HOH 11  411 344 HOH HOH D . 
P 10 HOH 12  412 146 HOH HOH D . 
P 10 HOH 13  413 25  HOH HOH D . 
P 10 HOH 14  414 250 HOH HOH D . 
P 10 HOH 15  415 191 HOH HOH D . 
P 10 HOH 16  416 207 HOH HOH D . 
P 10 HOH 17  417 226 HOH HOH D . 
P 10 HOH 18  418 47  HOH HOH D . 
P 10 HOH 19  419 116 HOH HOH D . 
P 10 HOH 20  420 228 HOH HOH D . 
P 10 HOH 21  421 538 HOH HOH D . 
P 10 HOH 22  422 16  HOH HOH D . 
P 10 HOH 23  423 262 HOH HOH D . 
P 10 HOH 24  424 3   HOH HOH D . 
P 10 HOH 25  425 536 HOH HOH D . 
P 10 HOH 26  426 19  HOH HOH D . 
P 10 HOH 27  427 37  HOH HOH D . 
P 10 HOH 28  428 58  HOH HOH D . 
P 10 HOH 29  429 1   HOH HOH D . 
P 10 HOH 30  430 75  HOH HOH D . 
P 10 HOH 31  431 406 HOH HOH D . 
P 10 HOH 32  432 470 HOH HOH D . 
P 10 HOH 33  433 182 HOH HOH D . 
P 10 HOH 34  434 155 HOH HOH D . 
P 10 HOH 35  435 69  HOH HOH D . 
P 10 HOH 36  436 261 HOH HOH D . 
P 10 HOH 37  437 38  HOH HOH D . 
P 10 HOH 38  438 24  HOH HOH D . 
P 10 HOH 39  439 270 HOH HOH D . 
P 10 HOH 40  440 35  HOH HOH D . 
P 10 HOH 41  441 221 HOH HOH D . 
P 10 HOH 42  442 394 HOH HOH D . 
P 10 HOH 43  443 12  HOH HOH D . 
P 10 HOH 44  444 507 HOH HOH D . 
P 10 HOH 45  445 307 HOH HOH D . 
P 10 HOH 46  446 133 HOH HOH D . 
P 10 HOH 47  447 264 HOH HOH D . 
P 10 HOH 48  448 107 HOH HOH D . 
P 10 HOH 49  449 187 HOH HOH D . 
P 10 HOH 50  450 9   HOH HOH D . 
P 10 HOH 51  451 337 HOH HOH D . 
P 10 HOH 52  452 213 HOH HOH D . 
P 10 HOH 53  453 26  HOH HOH D . 
P 10 HOH 54  454 83  HOH HOH D . 
P 10 HOH 55  455 104 HOH HOH D . 
P 10 HOH 56  456 147 HOH HOH D . 
P 10 HOH 57  457 275 HOH HOH D . 
P 10 HOH 58  458 506 HOH HOH D . 
P 10 HOH 59  459 60  HOH HOH D . 
P 10 HOH 60  460 240 HOH HOH D . 
P 10 HOH 61  461 324 HOH HOH D . 
P 10 HOH 62  462 68  HOH HOH D . 
P 10 HOH 63  463 156 HOH HOH D . 
P 10 HOH 64  464 64  HOH HOH D . 
P 10 HOH 65  465 105 HOH HOH D . 
P 10 HOH 66  466 73  HOH HOH D . 
P 10 HOH 67  467 225 HOH HOH D . 
P 10 HOH 68  468 31  HOH HOH D . 
P 10 HOH 69  469 15  HOH HOH D . 
P 10 HOH 70  470 263 HOH HOH D . 
P 10 HOH 71  471 194 HOH HOH D . 
P 10 HOH 72  472 362 HOH HOH D . 
P 10 HOH 73  473 518 HOH HOH D . 
P 10 HOH 74  474 203 HOH HOH D . 
P 10 HOH 75  475 163 HOH HOH D . 
P 10 HOH 76  476 84  HOH HOH D . 
P 10 HOH 77  477 99  HOH HOH D . 
P 10 HOH 78  478 359 HOH HOH D . 
P 10 HOH 79  479 190 HOH HOH D . 
P 10 HOH 80  480 249 HOH HOH D . 
P 10 HOH 81  481 94  HOH HOH D . 
P 10 HOH 82  482 234 HOH HOH D . 
P 10 HOH 83  483 79  HOH HOH D . 
P 10 HOH 84  484 106 HOH HOH D . 
P 10 HOH 85  485 396 HOH HOH D . 
P 10 HOH 86  486 128 HOH HOH D . 
P 10 HOH 87  487 416 HOH HOH D . 
P 10 HOH 88  488 33  HOH HOH D . 
P 10 HOH 89  489 129 HOH HOH D . 
P 10 HOH 90  490 30  HOH HOH D . 
P 10 HOH 91  491 254 HOH HOH D . 
P 10 HOH 92  492 322 HOH HOH D . 
P 10 HOH 93  493 217 HOH HOH D . 
P 10 HOH 94  494 365 HOH HOH D . 
P 10 HOH 95  495 201 HOH HOH D . 
P 10 HOH 96  496 497 HOH HOH D . 
P 10 HOH 97  497 387 HOH HOH D . 
P 10 HOH 98  498 350 HOH HOH D . 
P 10 HOH 99  499 174 HOH HOH D . 
P 10 HOH 100 500 7   HOH HOH D . 
P 10 HOH 101 501 386 HOH HOH D . 
P 10 HOH 102 502 131 HOH HOH D . 
P 10 HOH 103 503 452 HOH HOH D . 
P 10 HOH 104 504 161 HOH HOH D . 
P 10 HOH 105 505 287 HOH HOH D . 
P 10 HOH 106 506 292 HOH HOH D . 
P 10 HOH 107 507 113 HOH HOH D . 
P 10 HOH 108 508 119 HOH HOH D . 
P 10 HOH 109 509 283 HOH HOH D . 
P 10 HOH 110 510 319 HOH HOH D . 
P 10 HOH 111 511 423 HOH HOH D . 
P 10 HOH 112 512 36  HOH HOH D . 
P 10 HOH 113 513 260 HOH HOH D . 
P 10 HOH 114 514 455 HOH HOH D . 
P 10 HOH 115 515 373 HOH HOH D . 
P 10 HOH 116 516 309 HOH HOH D . 
P 10 HOH 117 517 246 HOH HOH D . 
P 10 HOH 118 518 91  HOH HOH D . 
P 10 HOH 119 519 229 HOH HOH D . 
P 10 HOH 120 520 378 HOH HOH D . 
P 10 HOH 121 521 303 HOH HOH D . 
P 10 HOH 122 522 153 HOH HOH D . 
P 10 HOH 123 523 398 HOH HOH D . 
P 10 HOH 124 524 360 HOH HOH D . 
P 10 HOH 125 525 469 HOH HOH D . 
P 10 HOH 126 526 508 HOH HOH D . 
P 10 HOH 127 527 330 HOH HOH D . 
P 10 HOH 128 528 498 HOH HOH D . 
P 10 HOH 129 529 313 HOH HOH D . 
P 10 HOH 130 530 537 HOH HOH D . 
P 10 HOH 131 531 454 HOH HOH D . 
P 10 HOH 132 532 334 HOH HOH D . 
P 10 HOH 133 533 277 HOH HOH D . 
P 10 HOH 134 534 491 HOH HOH D . 
P 10 HOH 135 535 383 HOH HOH D . 
P 10 HOH 136 536 505 HOH HOH D . 
P 10 HOH 137 537 214 HOH HOH D . 
P 10 HOH 138 538 422 HOH HOH D . 
P 10 HOH 139 539 541 HOH HOH D . 
P 10 HOH 140 540 391 HOH HOH D . 
P 10 HOH 141 541 327 HOH HOH D . 
P 10 HOH 142 542 377 HOH HOH D . 
P 10 HOH 143 543 235 HOH HOH D . 
P 10 HOH 144 544 289 HOH HOH D . 
P 10 HOH 145 545 495 HOH HOH D . 
P 10 HOH 146 546 456 HOH HOH D . 
P 10 HOH 147 547 534 HOH HOH D . 
P 10 HOH 148 548 175 HOH HOH D . 
P 10 HOH 149 549 453 HOH HOH D . 
P 10 HOH 150 550 408 HOH HOH D . 
P 10 HOH 151 551 276 HOH HOH D . 
P 10 HOH 152 552 434 HOH HOH D . 
Q 10 HOH 1   401 157 HOH HOH E . 
Q 10 HOH 2   402 167 HOH HOH E . 
Q 10 HOH 3   403 180 HOH HOH E . 
Q 10 HOH 4   404 77  HOH HOH E . 
Q 10 HOH 5   405 143 HOH HOH E . 
Q 10 HOH 6   406 150 HOH HOH E . 
Q 10 HOH 7   407 417 HOH HOH E . 
Q 10 HOH 8   408 10  HOH HOH E . 
Q 10 HOH 9   409 196 HOH HOH E . 
Q 10 HOH 10  410 339 HOH HOH E . 
Q 10 HOH 11  411 401 HOH HOH E . 
Q 10 HOH 12  412 493 HOH HOH E . 
Q 10 HOH 13  413 193 HOH HOH E . 
Q 10 HOH 14  414 62  HOH HOH E . 
Q 10 HOH 15  415 8   HOH HOH E . 
Q 10 HOH 16  416 42  HOH HOH E . 
Q 10 HOH 17  417 76  HOH HOH E . 
Q 10 HOH 18  418 139 HOH HOH E . 
Q 10 HOH 19  419 223 HOH HOH E . 
Q 10 HOH 20  420 315 HOH HOH E . 
Q 10 HOH 21  421 356 HOH HOH E . 
Q 10 HOH 22  422 265 HOH HOH E . 
Q 10 HOH 23  423 252 HOH HOH E . 
Q 10 HOH 24  424 375 HOH HOH E . 
Q 10 HOH 25  425 82  HOH HOH E . 
Q 10 HOH 26  426 300 HOH HOH E . 
Q 10 HOH 27  427 110 HOH HOH E . 
Q 10 HOH 28  428 140 HOH HOH E . 
Q 10 HOH 29  429 184 HOH HOH E . 
Q 10 HOH 30  430 218 HOH HOH E . 
Q 10 HOH 31  431 329 HOH HOH E . 
Q 10 HOH 32  432 29  HOH HOH E . 
Q 10 HOH 33  433 449 HOH HOH E . 
Q 10 HOH 34  434 2   HOH HOH E . 
Q 10 HOH 35  435 363 HOH HOH E . 
Q 10 HOH 36  436 46  HOH HOH E . 
Q 10 HOH 37  437 238 HOH HOH E . 
Q 10 HOH 38  438 178 HOH HOH E . 
Q 10 HOH 39  439 109 HOH HOH E . 
Q 10 HOH 40  440 227 HOH HOH E . 
Q 10 HOH 41  441 305 HOH HOH E . 
Q 10 HOH 42  442 219 HOH HOH E . 
Q 10 HOH 43  443 14  HOH HOH E . 
Q 10 HOH 44  444 88  HOH HOH E . 
Q 10 HOH 45  445 85  HOH HOH E . 
Q 10 HOH 46  446 50  HOH HOH E . 
Q 10 HOH 47  447 230 HOH HOH E . 
Q 10 HOH 48  448 172 HOH HOH E . 
Q 10 HOH 49  449 52  HOH HOH E . 
Q 10 HOH 50  450 130 HOH HOH E . 
Q 10 HOH 51  451 145 HOH HOH E . 
Q 10 HOH 52  452 169 HOH HOH E . 
Q 10 HOH 53  453 257 HOH HOH E . 
Q 10 HOH 54  454 148 HOH HOH E . 
Q 10 HOH 55  455 288 HOH HOH E . 
Q 10 HOH 56  456 70  HOH HOH E . 
Q 10 HOH 57  457 368 HOH HOH E . 
Q 10 HOH 58  458 241 HOH HOH E . 
Q 10 HOH 59  459 271 HOH HOH E . 
Q 10 HOH 60  460 114 HOH HOH E . 
Q 10 HOH 61  461 65  HOH HOH E . 
Q 10 HOH 62  462 268 HOH HOH E . 
Q 10 HOH 63  463 32  HOH HOH E . 
Q 10 HOH 64  464 516 HOH HOH E . 
Q 10 HOH 65  465 55  HOH HOH E . 
Q 10 HOH 66  466 290 HOH HOH E . 
Q 10 HOH 67  467 393 HOH HOH E . 
Q 10 HOH 68  468 251 HOH HOH E . 
Q 10 HOH 69  469 97  HOH HOH E . 
Q 10 HOH 70  470 472 HOH HOH E . 
Q 10 HOH 71  471 450 HOH HOH E . 
Q 10 HOH 72  472 13  HOH HOH E . 
Q 10 HOH 73  473 451 HOH HOH E . 
Q 10 HOH 74  474 159 HOH HOH E . 
Q 10 HOH 75  475 23  HOH HOH E . 
Q 10 HOH 76  476 49  HOH HOH E . 
Q 10 HOH 77  477 466 HOH HOH E . 
Q 10 HOH 78  478 256 HOH HOH E . 
Q 10 HOH 79  479 370 HOH HOH E . 
Q 10 HOH 80  480 389 HOH HOH E . 
Q 10 HOH 81  481 302 HOH HOH E . 
Q 10 HOH 82  482 331 HOH HOH E . 
Q 10 HOH 83  483 457 HOH HOH E . 
Q 10 HOH 84  484 514 HOH HOH E . 
Q 10 HOH 85  485 420 HOH HOH E . 
Q 10 HOH 86  486 395 HOH HOH E . 
Q 10 HOH 87  487 87  HOH HOH E . 
Q 10 HOH 88  488 543 HOH HOH E . 
Q 10 HOH 89  489 345 HOH HOH E . 
Q 10 HOH 90  490 397 HOH HOH E . 
Q 10 HOH 91  491 34  HOH HOH E . 
Q 10 HOH 92  492 27  HOH HOH E . 
Q 10 HOH 93  493 392 HOH HOH E . 
Q 10 HOH 94  494 255 HOH HOH E . 
Q 10 HOH 95  495 464 HOH HOH E . 
Q 10 HOH 96  496 511 HOH HOH E . 
Q 10 HOH 97  497 446 HOH HOH E . 
Q 10 HOH 98  498 353 HOH HOH E . 
Q 10 HOH 99  499 266 HOH HOH E . 
Q 10 HOH 100 500 407 HOH HOH E . 
Q 10 HOH 101 501 248 HOH HOH E . 
Q 10 HOH 102 502 267 HOH HOH E . 
Q 10 HOH 103 503 403 HOH HOH E . 
Q 10 HOH 104 504 509 HOH HOH E . 
Q 10 HOH 105 505 326 HOH HOH E . 
Q 10 HOH 106 506 471 HOH HOH E . 
Q 10 HOH 107 507 468 HOH HOH E . 
Q 10 HOH 108 508 460 HOH HOH E . 
Q 10 HOH 109 509 312 HOH HOH E . 
Q 10 HOH 110 510 232 HOH HOH E . 
Q 10 HOH 111 511 404 HOH HOH E . 
Q 10 HOH 112 512 127 HOH HOH E . 
Q 10 HOH 113 513 475 HOH HOH E . 
Q 10 HOH 114 514 152 HOH HOH E . 
Q 10 HOH 115 515 293 HOH HOH E . 
Q 10 HOH 116 516 459 HOH HOH E . 
Q 10 HOH 117 517 367 HOH HOH E . 
Q 10 HOH 118 518 492 HOH HOH E . 
Q 10 HOH 119 519 296 HOH HOH E . 
Q 10 HOH 120 520 380 HOH HOH E . 
Q 10 HOH 121 521 333 HOH HOH E . 
Q 10 HOH 122 522 102 HOH HOH E . 
Q 10 HOH 123 523 531 HOH HOH E . 
Q 10 HOH 124 524 413 HOH HOH E . 
Q 10 HOH 125 525 461 HOH HOH E . 
Q 10 HOH 126 526 301 HOH HOH E . 
Q 10 HOH 127 527 366 HOH HOH E . 
Q 10 HOH 128 528 510 HOH HOH E . 
Q 10 HOH 129 529 328 HOH HOH E . 
Q 10 HOH 130 530 463 HOH HOH E . 
Q 10 HOH 131 531 421 HOH HOH E . 
Q 10 HOH 132 532 474 HOH HOH E . 
Q 10 HOH 133 533 358 HOH HOH E . 
Q 10 HOH 134 534 467 HOH HOH E . 
Q 10 HOH 135 535 458 HOH HOH E . 
Q 10 HOH 136 536 424 HOH HOH E . 
Q 10 HOH 137 537 533 HOH HOH E . 
Q 10 HOH 138 538 499 HOH HOH E . 
Q 10 HOH 139 539 179 HOH HOH E . 
Q 10 HOH 140 540 465 HOH HOH E . 
Q 10 HOH 141 541 473 HOH HOH E . 
Q 10 HOH 142 542 80  HOH HOH E . 
Q 10 HOH 143 543 177 HOH HOH E . 
Q 10 HOH 144 544 496 HOH HOH E . 
Q 10 HOH 145 545 371 HOH HOH E . 
Q 10 HOH 146 546 513 HOH HOH E . 
Q 10 HOH 147 547 198 HOH HOH E . 
Q 10 HOH 148 548 462 HOH HOH E . 
Q 10 HOH 149 549 512 HOH HOH E . 
Q 10 HOH 150 550 494 HOH HOH E . 
Q 10 HOH 151 551 418 HOH HOH E . 
Q 10 HOH 152 552 342 HOH HOH E . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 50  ? CG  ? A ARG 53  CG  
2  1 Y 1 A ARG 50  ? CD  ? A ARG 53  CD  
3  1 Y 1 A ARG 50  ? NE  ? A ARG 53  NE  
4  1 Y 1 A ARG 50  ? CZ  ? A ARG 53  CZ  
5  1 Y 1 A ARG 50  ? NH1 ? A ARG 53  NH1 
6  1 Y 1 A ARG 50  ? NH2 ? A ARG 53  NH2 
7  1 Y 1 B LYS 128 ? CG  ? B LYS 128 CG  
8  1 Y 1 B LYS 128 ? CD  ? B LYS 128 CD  
9  1 Y 1 B LYS 128 ? CE  ? B LYS 128 CE  
10 1 Y 1 B LYS 128 ? NZ  ? B LYS 128 NZ  
11 1 Y 1 B GLN 136 ? CG  ? B GLN 136 CG  
12 1 Y 1 B GLN 136 ? CD  ? B GLN 136 CD  
13 1 Y 1 B GLN 136 ? OE1 ? B GLN 136 OE1 
14 1 Y 1 B GLN 136 ? NE2 ? B GLN 136 NE2 
15 1 Y 1 B GLU 162 ? CG  ? B GLU 162 CG  
16 1 Y 1 B GLU 162 ? CD  ? B GLU 162 CD  
17 1 Y 1 B GLU 162 ? OE1 ? B GLU 162 OE1 
18 1 Y 1 B GLU 162 ? OE2 ? B GLU 162 OE2 
19 1 Y 1 B THR 164 ? OG1 ? B THR 164 OG1 
20 1 Y 1 B THR 164 ? CG2 ? B THR 164 CG2 
21 1 Y 1 B GLN 166 ? CG  ? B GLN 166 CG  
22 1 Y 1 B GLN 166 ? CD  ? B GLN 166 CD  
23 1 Y 1 B GLN 166 ? OE1 ? B GLN 166 OE1 
24 1 Y 1 B GLN 166 ? NE2 ? B GLN 166 NE2 
25 1 Y 1 B ARG 167 ? CG  ? B ARG 167 CG  
26 1 Y 1 B ARG 167 ? CD  ? B ARG 167 CD  
27 1 Y 1 B ARG 167 ? NE  ? B ARG 167 NE  
28 1 Y 1 B ARG 167 ? CZ  ? B ARG 167 CZ  
29 1 Y 1 B ARG 167 ? NH1 ? B ARG 167 NH1 
30 1 Y 1 B ARG 167 ? NH2 ? B ARG 167 NH2 
31 1 Y 1 B GLN 181 ? CG  ? B GLN 181 CG  
32 1 Y 1 B GLN 181 ? CD  ? B GLN 181 CD  
33 1 Y 1 B GLN 181 ? OE1 ? B GLN 181 OE1 
34 1 Y 1 B GLN 181 ? NE2 ? B GLN 181 NE2 
35 1 Y 1 B GLN 194 ? CG  ? B GLN 196 CG  
36 1 Y 1 B GLN 194 ? CD  ? B GLN 196 CD  
37 1 Y 1 B GLN 194 ? OE1 ? B GLN 196 OE1 
38 1 Y 1 B GLN 194 ? NE2 ? B GLN 196 NE2 
39 1 Y 1 D GLN 155 ? CG  ? D GLN 141 CG  
40 1 Y 1 D GLN 155 ? CD  ? D GLN 141 CD  
41 1 Y 1 D GLN 155 ? OE1 ? D GLN 141 OE1 
42 1 Y 1 D GLN 155 ? NE2 ? D GLN 141 NE2 
43 1 Y 1 D LYS 162 ? CG  ? D LYS 148 CG  
44 1 Y 1 D LYS 162 ? CD  ? D LYS 148 CD  
45 1 Y 1 D LYS 162 ? CE  ? D LYS 148 CE  
46 1 Y 1 D LYS 162 ? NZ  ? D LYS 148 NZ  
47 1 Y 1 D ASP 163 ? CG  ? D ASP 149 CG  
48 1 Y 1 D ASP 163 ? OD1 ? D ASP 149 OD1 
49 1 Y 1 D ASP 163 ? OD2 ? D ASP 149 OD2 
50 1 Y 1 D SER 164 ? OG  ? D SER 150 OG  
51 1 Y 1 D LYS 192 ? CG  ? D LYS 178 CG  
52 1 Y 1 D LYS 192 ? CD  ? D LYS 178 CD  
53 1 Y 1 D LYS 192 ? CE  ? D LYS 178 CE  
54 1 Y 1 D LYS 192 ? NZ  ? D LYS 178 NZ  
55 1 Y 1 D ASP 194 ? CG  ? D ASP 180 CG  
56 1 Y 1 D ASP 194 ? OD1 ? D ASP 180 OD1 
57 1 Y 1 D ASP 194 ? OD2 ? D ASP 180 OD2 
58 1 Y 1 E LYS 131 ? CG  ? E LYS 117 CG  
59 1 Y 1 E LYS 131 ? CD  ? E LYS 117 CD  
60 1 Y 1 E LYS 131 ? CE  ? E LYS 117 CE  
61 1 Y 1 E LYS 131 ? NZ  ? E LYS 117 NZ  
62 1 Y 1 E ASN 196 ? CG  ? E ASN 182 CG  
63 1 Y 1 E ASN 196 ? OD1 ? E ASN 182 OD1 
64 1 Y 1 E ASN 196 ? ND2 ? E ASN 182 ND2 
65 1 Y 1 E GLU 231 ? CG  ? E GLU 217 CG  
66 1 Y 1 E GLU 231 ? CD  ? E GLU 217 CD  
67 1 Y 1 E GLU 231 ? OE1 ? E GLU 217 OE1 
68 1 Y 1 E GLU 231 ? OE2 ? E GLU 217 OE2 
69 1 Y 1 E ASN 232 ? CG  ? E ASN 218 CG  
70 1 Y 1 E ASN 232 ? OD1 ? E ASN 218 OD1 
71 1 Y 1 E ASN 232 ? ND2 ? E ASN 218 ND2 
72 1 Y 1 E GLU 234 ? CG  ? E GLU 220 CG  
73 1 Y 1 E GLU 234 ? CD  ? E GLU 220 CD  
74 1 Y 1 E GLU 234 ? OE1 ? E GLU 220 OE1 
75 1 Y 1 E GLU 234 ? OE2 ? E GLU 220 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.19.2_4158 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.19.2_4158 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   107.924 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EJI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     101.840 
_cell.length_a_esd                 ? 
_cell.length_b                     81.827 
_cell.length_b_esd                 ? 
_cell.length_c                     143.167 
_cell.length_c_esd                 ? 
_cell.volume                       1135144.173 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EJI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            'C 2y (x,y,-x+z)' 
_symmetry.space_group_name_H-M             'I 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EJI 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.98 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58.77 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '8% Tacsimate pH 8.0, 20-24% w/v PEG3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-08-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.95373 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'AUSTRALIAN SYNCHROTRON BEAMLINE MX2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.95373 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MX2 
_diffrn_source.pdbx_synchrotron_site       'Australian Synchrotron' 
# 
_reflns.B_iso_Wilson_estimate                          27.11 
_reflns.entry_id                                       9EJI 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.2 
_reflns.d_resolution_low                               48.45 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     56955 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.996 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.20 
_reflns_shell.d_res_low                                     2.26 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4668 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.974 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               34.46 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9EJI 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.20 
_refine.ls_d_res_low                             48.45 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     56912 
_refine.ls_number_reflns_R_free                  2955 
_refine.ls_number_reflns_R_work                  53957 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.92 
_refine.ls_percent_reflns_R_free                 5.19 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1871 
_refine.ls_R_factor_R_free                       0.2202 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1852 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 24.1253 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2359 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.20 
_refine_hist.d_res_low                        48.45 
_refine_hist.number_atoms_solvent             524 
_refine_hist.number_atoms_total               7042 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6442 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         76 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0022 ? 6676 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5693 ? 9078 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0429 ? 1004 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0046 ? 1183 ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 5.3095 ? 902  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.20 2.24  . . 122 2566 99.78  . . . . 0.2209 . . . . . . . . . . . 0.2772 
'X-RAY DIFFRACTION' 2.24 2.27  . . 144 2572 99.71  . . . . 0.2123 . . . . . . . . . . . 0.3079 
'X-RAY DIFFRACTION' 2.27 2.32  . . 159 2508 99.93  . . . . 0.2167 . . . . . . . . . . . 0.2560 
'X-RAY DIFFRACTION' 2.32 2.36  . . 134 2555 99.85  . . . . 0.2088 . . . . . . . . . . . 0.2815 
'X-RAY DIFFRACTION' 2.36 2.41  . . 152 2546 99.93  . . . . 0.2153 . . . . . . . . . . . 0.2486 
'X-RAY DIFFRACTION' 2.41 2.46  . . 125 2593 100.00 . . . . 0.2093 . . . . . . . . . . . 0.2998 
'X-RAY DIFFRACTION' 2.46 2.52  . . 140 2535 99.93  . . . . 0.2119 . . . . . . . . . . . 0.2657 
'X-RAY DIFFRACTION' 2.52 2.58  . . 140 2542 100.00 . . . . 0.2080 . . . . . . . . . . . 0.2404 
'X-RAY DIFFRACTION' 2.58 2.65  . . 142 2579 99.82  . . . . 0.2058 . . . . . . . . . . . 0.2884 
'X-RAY DIFFRACTION' 2.65 2.73  . . 125 2581 100.00 . . . . 0.2150 . . . . . . . . . . . 0.2536 
'X-RAY DIFFRACTION' 2.73 2.82  . . 136 2580 99.89  . . . . 0.2128 . . . . . . . . . . . 0.2620 
'X-RAY DIFFRACTION' 2.82 2.92  . . 150 2552 99.93  . . . . 0.2085 . . . . . . . . . . . 0.2495 
'X-RAY DIFFRACTION' 2.92 3.03  . . 156 2531 99.96  . . . . 0.2171 . . . . . . . . . . . 0.2461 
'X-RAY DIFFRACTION' 3.03 3.17  . . 118 2597 100.00 . . . . 0.1888 . . . . . . . . . . . 0.2433 
'X-RAY DIFFRACTION' 3.17 3.34  . . 157 2525 99.96  . . . . 0.1833 . . . . . . . . . . . 0.1937 
'X-RAY DIFFRACTION' 3.34 3.55  . . 150 2590 100.00 . . . . 0.1767 . . . . . . . . . . . 0.1953 
'X-RAY DIFFRACTION' 3.55 3.82  . . 133 2575 99.96  . . . . 0.1701 . . . . . . . . . . . 0.2435 
'X-RAY DIFFRACTION' 3.82 4.21  . . 150 2575 100.00 . . . . 0.1631 . . . . . . . . . . . 0.1759 
'X-RAY DIFFRACTION' 4.21 4.82  . . 146 2593 100.00 . . . . 0.1398 . . . . . . . . . . . 0.1675 
'X-RAY DIFFRACTION' 4.82 6.07  . . 139 2600 100.00 . . . . 0.1618 . . . . . . . . . . . 0.1838 
'X-RAY DIFFRACTION' 6.07 48.45 . . 137 2662 99.68  . . . . 0.1881 . . . . . . . . . . . 0.1897 
# 
_struct.entry_id                     9EJI 
_struct.title                        'Peptide-independent T cell receptor recognition of HLA-DQ2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EJI 
_struct_keywords.text            'T cell receptor, immune receptor, human leukocyte antigen, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1  ? 
B N N 2  ? 
C N N 3  ? 
D N N 4  ? 
E N N 5  ? 
F N N 6  ? 
G N N 7  ? 
H N N 8  ? 
I N N 9  ? 
J N N 9  ? 
K N N 9  ? 
L N N 7  ? 
M N N 10 ? 
N N N 10 ? 
O N N 10 ? 
P N N 10 ? 
Q N N 10 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP Q08AS3_HUMAN     Q08AS3     ? 1 
;EDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYVDLERKETVWKLPLFHRLRFDPQFALTNIAVLKHNLNILIKRSN
STAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSAD
EIYDCKVEHWGLDEPLLKHWEPE
;
24 
2 UNP A0A0U5IHY9_HUMAN A0A0U5IHY9 ? 2 
;RDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCR
HNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQ
;
33 
3 PDB 9EJI             9EJI       ? 3 ? 1  
4 PDB 9EJI             9EJI       ? 4 ? 1  
5 PDB 9EJI             9EJI       ? 5 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9EJI A 1 ? 183 ? Q08AS3     24 ? 206 ? -2 180 
2 2 9EJI B 1 ? 196 ? A0A0U5IHY9 33 ? 228 ? 1  194 
3 3 9EJI C 1 ? 13  ? 9EJI       0  ? 12  ? 0  12  
4 4 9EJI D 1 ? 204 ? 9EJI       -1 ? 218 ? -1 218 
5 5 9EJI E 1 ? 242 ? 9EJI       2  ? 256 ? 2  256 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9EJI 
_struct_ref_seq_dif.mon_id                       THR 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      184 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   Q08AS3 
_struct_ref_seq_dif.db_mon_id                    ? 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          ? 
_struct_ref_seq_dif.details                      'expression tag' 
_struct_ref_seq_dif.pdbx_auth_seq_num            181 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'surface plasmon resonance' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 57  ? SER A 79  ? ASP A 54  SER A 76  1 ? 23 
HELX_P HELX_P2  AA2 THR B 51  ? LEU B 53  ? THR B 51  LEU B 53  5 ? 3  
HELX_P HELX_P3  AA3 GLY B 54  ? GLN B 64  ? GLY B 54  GLN B 64  1 ? 11 
HELX_P HELX_P4  AA4 GLN B 64  ? VAL B 78  ? GLN B 64  VAL B 78  1 ? 15 
HELX_P HELX_P5  AA5 VAL B 78  ? ARG B 88  ? VAL B 78  ARG B 88  1 ? 11 
HELX_P HELX_P6  AA6 THR B 89  ? ARG B 93  ? THR B 89  ARG B 93  5 ? 5  
HELX_P HELX_P7  AA7 LYS D 81  ? SER D 85  ? LYS D 95  SER D 99  5 ? 5  
HELX_P HELX_P8  AA8 ALA D 182 ? ALA D 186 ? ALA D 196 ALA D 200 5 ? 5  
HELX_P HELX_P9  AA9 GLU E 81  ? SER E 85  ? GLU E 95  SER E 99  5 ? 5  
HELX_P HELX_P10 AB1 ASP E 114 ? VAL E 118 ? ASP E 128 VAL E 132 5 ? 5  
HELX_P HELX_P11 AB2 SER E 129 ? GLN E 137 ? SER E 143 GLN E 151 1 ? 9  
HELX_P HELX_P12 AB3 ALA E 196 ? ASN E 201 ? ALA E 210 ASN E 215 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 109 SG  ? ? ? 1_555 A CYS 165 SG ? ? A CYS 106 A CYS 162 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf2 disulf ?    ? B CYS 15  SG  ? ? ? 1_555 B CYS 79  SG ? ? B CYS 15  B CYS 79  1_555 ? ? ? ? ? ? ? 2.036 ? ?               
disulf3 disulf ?    ? B CYS 117 SG  ? ? ? 1_555 B CYS 173 SG ? ? B CYS 117 B CYS 173 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf4 disulf ?    ? D CYS 25  SG  ? ? ? 1_555 D CYS 90  SG ? ? D CYS 23  D CYS 104 1_555 ? ? ? ? ? ? ? 2.041 ? ?               
disulf5 disulf ?    ? D CYS 133 SG  ? ? ? 1_555 D CYS 183 SG ? ? D CYS 147 D CYS 197 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf6 disulf ?    ? D CYS 158 SG  ? ? ? 1_555 E CYS 169 SG ? ? D CYS 172 E CYS 183 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf7 disulf ?    ? E CYS 22  SG  ? ? ? 1_555 E CYS 90  SG ? ? E CYS 23  E CYS 104 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf8 disulf ?    ? E CYS 143 SG  ? ? ? 1_555 E CYS 208 SG ? ? E CYS 157 E CYS 222 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1 covale one  ? A ASN 120 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 117 F NAG 1   1_555 ? ? ? ? ? ? ? 1.437 ? N-Glycosylation 
covale2 covale one  ? B ASN 19  ND2 ? ? ? 1_555 H NAG .   C1 ? ? B ASN 19  B NAG 201 1_555 ? ? ? ? ? ? ? 1.438 ? N-Glycosylation 
covale3 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN A 120 ? NAG F 1   ? 1_555 ASN A 117 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG H .   ? ASN B 19  ? NAG B 201 ? 1_555 ASN B 19  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  CYS A 109 ? CYS A 165 ? CYS A 106 ? 1_555 CYS A 162 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4  CYS B 15  ? CYS B 79  ? CYS B 15  ? 1_555 CYS B 79  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS B 117 ? CYS B 173 ? CYS B 117 ? 1_555 CYS B 173 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS D 25  ? CYS D 90  ? CYS D 23  ? 1_555 CYS D 104 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS D 133 ? CYS D 183 ? CYS D 147 ? 1_555 CYS D 197 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS D 158 ? CYS E 169 ? CYS D 172 ? 1_555 CYS E 183 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS E 22  ? CYS E 90  ? CYS E 23  ? 1_555 CYS E 104 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS E 143 ? CYS E 208 ? CYS E 157 ? 1_555 CYS E 222 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 11  A . ? TYR 8   A GLY 12  A ? GLY 9   A 1 -1.75 
2 PHE 115 A . ? PHE 112 A PRO 116 A ? PRO 113 A 1 -0.59 
3 TYR 123 B . ? TYR 123 B PRO 124 B ? PRO 124 B 1 3.60  
4 THR 6   E . ? THR 7   E PRO 7   E ? PRO 8   E 1 -5.62 
5 PHE 149 E . ? PHE 163 E PRO 150 E ? PRO 164 E 1 -0.21 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 5 ? 
AA9 ? 5 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
AB5 ? 6 ? 
AB6 ? 4 ? 
AB7 ? 4 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 43  ? TRP A 46  ? GLU A 40  TRP A 43  
AA1 2 ASP A 32  ? ASP A 38  ? ASP A 29  ASP A 35  
AA1 3 SER A 22  ? PHE A 29  ? SER A 19  PHE A 26  
AA1 4 HIS A 7   ? GLN A 17  ? HIS A 4   GLN A 14  
AA1 5 VAL B 8   ? THR B 18  ? VAL B 8   THR B 18  
AA1 6 ARG B 23  ? TYR B 32  ? ARG B 23  TYR B 32  
AA1 7 GLU B 35  ? ASP B 41  ? GLU B 35  ASP B 41  
AA1 8 PHE B 47  ? ALA B 49  ? PHE B 47  ALA B 49  
AA2 1 GLU A 90  ? SER A 95  ? GLU A 87  SER A 92  
AA2 2 ASN A 105 ? ILE A 114 ? ASN A 102 ILE A 111 
AA2 3 PHE A 147 ? PHE A 155 ? PHE A 144 PHE A 152 
AA2 4 VAL A 134 ? GLU A 136 ? VAL A 131 GLU A 133 
AA3 1 GLU A 90  ? SER A 95  ? GLU A 87  SER A 92  
AA3 2 ASN A 105 ? ILE A 114 ? ASN A 102 ILE A 111 
AA3 3 PHE A 147 ? PHE A 155 ? PHE A 144 PHE A 152 
AA3 4 LEU A 140 ? SER A 141 ? LEU A 137 SER A 138 
AA4 1 HIS A 128 ? VAL A 130 ? HIS A 125 VAL A 127 
AA4 2 ASN A 120 ? SER A 125 ? ASN A 117 SER A 122 
AA4 3 TYR A 163 ? GLU A 168 ? TYR A 160 GLU A 165 
AA4 4 LEU A 176 ? TRP A 180 ? LEU A 173 TRP A 177 
AA5 1 THR B 98  ? PRO B 103 ? THR B 98  PRO B 103 
AA5 2 LEU B 114 ? PHE B 122 ? LEU B 114 PHE B 122 
AA5 3 PHE B 155 ? GLU B 162 ? PHE B 155 GLU B 162 
AA5 4 VAL B 142 ? SER B 144 ? VAL B 142 SER B 144 
AA6 1 THR B 98  ? PRO B 103 ? THR B 98  PRO B 103 
AA6 2 LEU B 114 ? PHE B 122 ? LEU B 114 PHE B 122 
AA6 3 PHE B 155 ? GLU B 162 ? PHE B 155 GLU B 162 
AA6 4 ILE B 148 ? ARG B 149 ? ILE B 148 ARG B 149 
AA7 1 GLN B 136 ? GLU B 138 ? GLN B 136 GLU B 138 
AA7 2 LYS B 128 ? ARG B 133 ? LYS B 128 ARG B 133 
AA7 3 TYR B 171 ? GLU B 176 ? TYR B 171 GLU B 176 
AA7 4 ILE B 184 ? TRP B 188 ? ILE B 184 TRP B 188 
AA8 1 VAL D 6   ? GLN D 8   ? VAL D 4   GLN D 6   
AA8 2 VAL D 21  ? TYR D 27  ? VAL D 19  TYR D 25  
AA8 3 TYR D 72  ? ILE D 77  ? TYR D 86  ILE D 91  
AA8 4 PHE D 62  ? ASN D 67  ? PHE D 76  ASN D 81  
AA8 5 ASN D 57  ? ASP D 59  ? ASN D 65  ASP D 68  
AA9 1 PHE D 13  ? PRO D 16  ? PHE D 11  PRO D 14  
AA9 2 THR D 104 ? SER D 109 ? THR D 118 SER D 123 
AA9 3 ALA D 86  ? GLY D 94  ? ALA D 100 GLY D 108 
AA9 4 SER D 34  ? GLN D 40  ? SER D 38  GLN D 44  
AA9 5 PRO D 46  ? SER D 51  ? PRO D 50  SER D 55  
AB1 1 PHE D 13  ? PRO D 16  ? PHE D 11  PRO D 14  
AB1 2 THR D 104 ? SER D 109 ? THR D 118 SER D 123 
AB1 3 ALA D 86  ? GLY D 94  ? ALA D 100 GLY D 108 
AB1 4 LYS D 97  ? PHE D 100 ? LYS D 111 PHE D 114 
AB2 1 ALA D 118 ? GLN D 121 ? ALA D 132 GLN D 135 
AB2 2 SER D 131 ? THR D 136 ? SER D 145 THR D 150 
AB2 3 PHE D 167 ? SER D 176 ? PHE D 181 SER D 190 
AB2 4 TYR D 153 ? ILE D 154 ? TYR D 167 ILE D 168 
AB3 1 ALA D 118 ? GLN D 121 ? ALA D 132 GLN D 135 
AB3 2 SER D 131 ? THR D 136 ? SER D 145 THR D 150 
AB3 3 PHE D 167 ? SER D 176 ? PHE D 181 SER D 190 
AB3 4 CYS D 158 ? MET D 162 ? CYS D 172 MET D 176 
AB4 1 THR E 4   ? THR E 6   ? THR E 5   THR E 7   
AB4 2 VAL E 18  ? SER E 23  ? VAL E 19  SER E 24  
AB4 3 SER E 73  ? VAL E 77  ? SER E 87  VAL E 91  
AB4 4 PHE E 63  ? GLN E 67  ? PHE E 76  GLN E 80  
AB5 1 TYR E 9   ? THR E 13  ? TYR E 10  THR E 14  
AB5 2 SER E 107 ? LEU E 112 ? SER E 121 LEU E 126 
AB5 3 ALA E 86  ? SER E 93  ? ALA E 100 SER E 107 
AB5 4 SER E 30  ? GLN E 36  ? SER E 38  GLN E 44  
AB5 5 GLN E 43  ? PHE E 49  ? GLN E 51  PHE E 57  
AB5 6 THR E 52  ? LYS E 56  ? THR E 64  LYS E 68  
AB6 1 TYR E 9   ? THR E 13  ? TYR E 10  THR E 14  
AB6 2 SER E 107 ? LEU E 112 ? SER E 121 LEU E 126 
AB6 3 ALA E 86  ? SER E 93  ? ALA E 100 SER E 107 
AB6 4 PHE E 102 ? PHE E 103 ? PHE E 116 PHE E 117 
AB7 1 GLU E 122 ? PHE E 126 ? GLU E 136 PHE E 140 
AB7 2 LYS E 138 ? PHE E 148 ? LYS E 152 PHE E 162 
AB7 3 TYR E 186 ? SER E 195 ? TYR E 200 SER E 209 
AB7 4 VAL E 168 ? THR E 170 ? VAL E 182 THR E 184 
AB8 1 GLU E 122 ? PHE E 126 ? GLU E 136 PHE E 140 
AB8 2 LYS E 138 ? PHE E 148 ? LYS E 152 PHE E 162 
AB8 3 TYR E 186 ? SER E 195 ? TYR E 200 SER E 209 
AB8 4 LEU E 175 ? LYS E 176 ? LEU E 189 LYS E 190 
AB9 1 LYS E 162 ? VAL E 164 ? LYS E 176 VAL E 178 
AB9 2 VAL E 153 ? VAL E 159 ? VAL E 167 VAL E 173 
AB9 3 HIS E 205 ? PHE E 212 ? HIS E 219 PHE E 226 
AB9 4 GLN E 231 ? TRP E 238 ? GLN E 245 TRP E 252 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLU A 43  ? O GLU A 40  N ASP A 38  ? N ASP A 35  
AA1 2 3 O GLU A 34  ? O GLU A 31  N HIS A 27  ? N HIS A 24  
AA1 3 4 O THR A 26  ? O THR A 23  N VAL A 13  ? N VAL A 10  
AA1 4 5 N TYR A 11  ? N TYR A 8   O GLY B 13  ? O GLY B 13  
AA1 5 6 N GLN B 10  ? N GLN B 10  O ILE B 31  ? O ILE B 31  
AA1 6 7 N TYR B 32  ? N TYR B 32  O GLU B 35  ? O GLU B 35  
AA1 7 8 N ARG B 39  ? N ARG B 39  O ARG B 48  ? O ARG B 48  
AA2 1 2 N GLU A 90  ? N GLU A 87  O ASP A 112 ? O ASP A 109 
AA2 2 3 N ILE A 114 ? N ILE A 111 O PHE A 147 ? O PHE A 144 
AA2 3 4 O TYR A 152 ? O TYR A 149 N SER A 135 ? N SER A 132 
AA3 1 2 N GLU A 90  ? N GLU A 87  O ASP A 112 ? O ASP A 109 
AA3 2 3 N ILE A 114 ? N ILE A 111 O PHE A 147 ? O PHE A 144 
AA3 3 4 O PHE A 148 ? O PHE A 145 N LEU A 140 ? N LEU A 137 
AA4 1 2 O HIS A 128 ? O HIS A 125 N SER A 125 ? N SER A 122 
AA4 2 3 N THR A 122 ? N THR A 119 O LYS A 166 ? O LYS A 163 
AA4 3 4 N VAL A 167 ? N VAL A 164 O LEU A 176 ? O LEU A 173 
AA5 1 2 N THR B 100 ? N THR B 100 O SER B 118 ? O SER B 118 
AA5 2 3 N CYS B 117 ? N CYS B 117 O VAL B 159 ? O VAL B 159 
AA5 3 4 O MET B 160 ? O MET B 160 N VAL B 143 ? N VAL B 143 
AA6 1 2 N THR B 100 ? N THR B 100 O SER B 118 ? O SER B 118 
AA6 2 3 N CYS B 117 ? N CYS B 117 O VAL B 159 ? O VAL B 159 
AA6 3 4 O GLN B 156 ? O GLN B 156 N ILE B 148 ? N ILE B 148 
AA7 1 2 O GLN B 136 ? O GLN B 136 N ARG B 133 ? N ARG B 133 
AA7 2 3 N LYS B 128 ? N LYS B 128 O GLU B 176 ? O GLU B 176 
AA7 3 4 N TYR B 171 ? N TYR B 171 O TRP B 188 ? O TRP B 188 
AA8 1 2 N GLU D 7   ? N GLU D 5   O THR D 26  ? O THR D 24  
AA8 2 3 N CYS D 25  ? N CYS D 23  O ILE D 73  ? O ILE D 87  
AA8 3 4 O LEU D 76  ? O LEU D 90  N THR D 63  ? N THR D 77  
AA8 4 5 O PHE D 62  ? O PHE D 76  N ASP D 59  ? N ASP D 68  
AA9 1 2 N PHE D 13  ? N PHE D 11  O LEU D 107 ? O LEU D 121 
AA9 2 3 O LEU D 106 ? O LEU D 120 N ALA D 86  ? N ALA D 100 
AA9 3 4 O MET D 93  ? O MET D 107 N SER D 34  ? N SER D 38  
AA9 4 5 N TRP D 37  ? N TRP D 41  O LEU D 49  ? O LEU D 53  
AB1 1 2 N PHE D 13  ? N PHE D 11  O LEU D 107 ? O LEU D 121 
AB1 2 3 O LEU D 106 ? O LEU D 120 N ALA D 86  ? N ALA D 100 
AB1 3 4 N GLY D 94  ? N GLY D 108 O LYS D 97  ? O LYS D 111 
AB2 1 2 N TYR D 120 ? N TYR D 134 O LEU D 134 ? O LEU D 148 
AB2 2 3 N CYS D 133 ? N CYS D 147 O ALA D 174 ? O ALA D 188 
AB2 3 4 O TRP D 175 ? O TRP D 189 N TYR D 153 ? N TYR D 167 
AB3 1 2 N TYR D 120 ? N TYR D 134 O LEU D 134 ? O LEU D 148 
AB3 2 3 N CYS D 133 ? N CYS D 147 O ALA D 174 ? O ALA D 188 
AB3 3 4 O PHE D 167 ? O PHE D 181 N MET D 162 ? N MET D 176 
AB4 1 2 N THR E 6   ? N THR E 7   O SER E 21  ? O SER E 22  
AB4 2 3 N LEU E 20  ? N LEU E 21  O MET E 75  ? O MET E 89  
AB4 3 4 O ASN E 76  ? O ASN E 90  N SER E 64  ? N SER E 77  
AB5 1 2 N LYS E 12  ? N LYS E 13  O LEU E 112 ? O LEU E 126 
AB5 2 3 O SER E 107 ? O SER E 121 N TYR E 88  ? N TYR E 102 
AB5 3 4 O LEU E 89  ? O LEU E 103 N TYR E 34  ? N TYR E 42  
AB5 4 5 N VAL E 31  ? N VAL E 39  O TYR E 48  ? O TYR E 56  
AB5 5 6 N GLU E 47  ? N GLU E 55  O ARG E 54  ? O ARG E 66  
AB6 1 2 N LYS E 12  ? N LYS E 13  O LEU E 112 ? O LEU E 126 
AB6 2 3 O SER E 107 ? O SER E 121 N TYR E 88  ? N TYR E 102 
AB6 3 4 N SER E 92  ? N SER E 106 O PHE E 102 ? O PHE E 116 
AB7 1 2 N PHE E 126 ? N PHE E 140 O VAL E 142 ? O VAL E 156 
AB7 2 3 N LEU E 141 ? N LEU E 155 O LEU E 192 ? O LEU E 206 
AB7 3 4 O ARG E 191 ? O ARG E 205 N CYS E 169 ? N CYS E 183 
AB8 1 2 N PHE E 126 ? N PHE E 140 O VAL E 142 ? O VAL E 156 
AB8 2 3 N LEU E 141 ? N LEU E 155 O LEU E 192 ? O LEU E 206 
AB8 3 4 O ALA E 187 ? O ALA E 201 N LEU E 175 ? N LEU E 189 
AB9 1 2 O LYS E 162 ? O LYS E 176 N VAL E 159 ? N VAL E 173 
AB9 2 3 N SER E 156 ? N SER E 170 O GLN E 209 ? O GLN E 223 
AB9 3 4 N PHE E 212 ? N PHE E 226 O GLN E 231 ? O GLN E 245 
# 
_pdbx_entry_details.entry_id                   9EJI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NZ D LYS 171 ? ? O D HOH 401 ? ? 2.16 
2 1 O  B HOH 301 ? ? O B HOH 389 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR A 8   ? ? -119.35 76.42   
2  1 PRO A 18  ? ? -33.31  97.06   
3  1 ASN B 33  ? ? 54.46   -112.09 
4  1 THR B 89  ? ? -130.30 -89.56  
5  1 PRO B 124 ? ? -78.47  -169.17 
6  1 PRO B 165 ? ? -52.81  104.35  
7  1 ARG B 167 ? ? 59.71   -138.37 
8  1 PRO D 8   ? ? -74.66  -88.30  
9  1 LYS D 48  ? ? -118.32 -169.00 
10 1 ALA D 100 ? ? -174.79 -178.67 
11 1 GLN E 48  ? ? -135.71 -45.84  
12 1 LEU E 53  ? ? -96.38  -65.43  
13 1 GLU E 63  ? ? 72.40   -3.28   
14 1 SER E 85  ? ? 70.53   -5.19   
15 1 ASP E 128 ? ? -173.60 132.67  
16 1 ASP E 165 ? ? -83.37  47.49   
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    D 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     550 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   P 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 -x,y,-z             
3 x+1/2,y+1/2,z+1/2   
4 -x+1/2,y+1/2,-z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLU -2  ? A GLU 1   
2  1 Y 1 A ASP -1  ? A ASP 2   
3  1 Y 1 B ARG 1   ? B ARG 1   
4  1 Y 1 B ASP 2   ? B ASP 2   
5  1 Y 1 B ARG 105 ? B ARG 105 
6  1 Y 1 B THR 106 ? B THR 106 
7  1 Y 1 B GLU 107 ? B GLU 107 
8  1 Y 1 B ALA 108 ? B ALA 108 
9  1 Y 1 B LEU 109 ? B LEU 109 
10 1 Y 1 B ASN 110 ? B ASN 110 
11 1 Y 1 B HIS 111 ? B HIS 111 
12 1 Y 1 B HIS 112 ? B HIS 112 
13 1 Y 1 B ALA 189 A B ALA 190 
14 1 Y 1 B GLN 189 B B GLN 191 
15 1 Y 1 B SER 189 C B SER 192 
16 1 Y 1 B GLU 189 D B GLU 193 
17 1 Y 1 B SER 189 E B SER 194 
18 1 Y 1 D MET -1  ? D MET 1   
19 1 Y 1 D GLN 0   ? D GLN 2   
20 1 Y 1 D GLU 216 ? D GLU 202 
21 1 Y 1 D SER 217 ? D SER 203 
22 1 Y 1 D SER 218 ? D SER 204 
23 1 Y 1 E MET 2   ? E MET 1   
24 1 N 0 E ACT 301 ? K ACT ?   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ACT C    C N N 1   
ACT O    O N N 2   
ACT OXT  O N N 3   
ACT CH3  C N N 4   
ACT H1   H N N 5   
ACT H2   H N N 6   
ACT H3   H N N 7   
ALA N    N N N 8   
ALA CA   C N S 9   
ALA C    C N N 10  
ALA O    O N N 11  
ALA CB   C N N 12  
ALA OXT  O N N 13  
ALA H    H N N 14  
ALA H2   H N N 15  
ALA HA   H N N 16  
ALA HB1  H N N 17  
ALA HB2  H N N 18  
ALA HB3  H N N 19  
ALA HXT  H N N 20  
ARG N    N N N 21  
ARG CA   C N S 22  
ARG C    C N N 23  
ARG O    O N N 24  
ARG CB   C N N 25  
ARG CG   C N N 26  
ARG CD   C N N 27  
ARG NE   N N N 28  
ARG CZ   C N N 29  
ARG NH1  N N N 30  
ARG NH2  N N N 31  
ARG OXT  O N N 32  
ARG H    H N N 33  
ARG H2   H N N 34  
ARG HA   H N N 35  
ARG HB2  H N N 36  
ARG HB3  H N N 37  
ARG HG2  H N N 38  
ARG HG3  H N N 39  
ARG HD2  H N N 40  
ARG HD3  H N N 41  
ARG HE   H N N 42  
ARG HH11 H N N 43  
ARG HH12 H N N 44  
ARG HH21 H N N 45  
ARG HH22 H N N 46  
ARG HXT  H N N 47  
ASN N    N N N 48  
ASN CA   C N S 49  
ASN C    C N N 50  
ASN O    O N N 51  
ASN CB   C N N 52  
ASN CG   C N N 53  
ASN OD1  O N N 54  
ASN ND2  N N N 55  
ASN OXT  O N N 56  
ASN H    H N N 57  
ASN H2   H N N 58  
ASN HA   H N N 59  
ASN HB2  H N N 60  
ASN HB3  H N N 61  
ASN HD21 H N N 62  
ASN HD22 H N N 63  
ASN HXT  H N N 64  
ASP N    N N N 65  
ASP CA   C N S 66  
ASP C    C N N 67  
ASP O    O N N 68  
ASP CB   C N N 69  
ASP CG   C N N 70  
ASP OD1  O N N 71  
ASP OD2  O N N 72  
ASP OXT  O N N 73  
ASP H    H N N 74  
ASP H2   H N N 75  
ASP HA   H N N 76  
ASP HB2  H N N 77  
ASP HB3  H N N 78  
ASP HD2  H N N 79  
ASP HXT  H N N 80  
CYS N    N N N 81  
CYS CA   C N R 82  
CYS C    C N N 83  
CYS O    O N N 84  
CYS CB   C N N 85  
CYS SG   S N N 86  
CYS OXT  O N N 87  
CYS H    H N N 88  
CYS H2   H N N 89  
CYS HA   H N N 90  
CYS HB2  H N N 91  
CYS HB3  H N N 92  
CYS HG   H N N 93  
CYS HXT  H N N 94  
GLN N    N N N 95  
GLN CA   C N S 96  
GLN C    C N N 97  
GLN O    O N N 98  
GLN CB   C N N 99  
GLN CG   C N N 100 
GLN CD   C N N 101 
GLN OE1  O N N 102 
GLN NE2  N N N 103 
GLN OXT  O N N 104 
GLN H    H N N 105 
GLN H2   H N N 106 
GLN HA   H N N 107 
GLN HB2  H N N 108 
GLN HB3  H N N 109 
GLN HG2  H N N 110 
GLN HG3  H N N 111 
GLN HE21 H N N 112 
GLN HE22 H N N 113 
GLN HXT  H N N 114 
GLU N    N N N 115 
GLU CA   C N S 116 
GLU C    C N N 117 
GLU O    O N N 118 
GLU CB   C N N 119 
GLU CG   C N N 120 
GLU CD   C N N 121 
GLU OE1  O N N 122 
GLU OE2  O N N 123 
GLU OXT  O N N 124 
GLU H    H N N 125 
GLU H2   H N N 126 
GLU HA   H N N 127 
GLU HB2  H N N 128 
GLU HB3  H N N 129 
GLU HG2  H N N 130 
GLU HG3  H N N 131 
GLU HE2  H N N 132 
GLU HXT  H N N 133 
GLY N    N N N 134 
GLY CA   C N N 135 
GLY C    C N N 136 
GLY O    O N N 137 
GLY OXT  O N N 138 
GLY H    H N N 139 
GLY H2   H N N 140 
GLY HA2  H N N 141 
GLY HA3  H N N 142 
GLY HXT  H N N 143 
GOL C1   C N N 144 
GOL O1   O N N 145 
GOL C2   C N N 146 
GOL O2   O N N 147 
GOL C3   C N N 148 
GOL O3   O N N 149 
GOL H11  H N N 150 
GOL H12  H N N 151 
GOL HO1  H N N 152 
GOL H2   H N N 153 
GOL HO2  H N N 154 
GOL H31  H N N 155 
GOL H32  H N N 156 
GOL HO3  H N N 157 
HIS N    N N N 158 
HIS CA   C N S 159 
HIS C    C N N 160 
HIS O    O N N 161 
HIS CB   C N N 162 
HIS CG   C Y N 163 
HIS ND1  N Y N 164 
HIS CD2  C Y N 165 
HIS CE1  C Y N 166 
HIS NE2  N Y N 167 
HIS OXT  O N N 168 
HIS H    H N N 169 
HIS H2   H N N 170 
HIS HA   H N N 171 
HIS HB2  H N N 172 
HIS HB3  H N N 173 
HIS HD1  H N N 174 
HIS HD2  H N N 175 
HIS HE1  H N N 176 
HIS HE2  H N N 177 
HIS HXT  H N N 178 
HOH O    O N N 179 
HOH H1   H N N 180 
HOH H2   H N N 181 
ILE N    N N N 182 
ILE CA   C N S 183 
ILE C    C N N 184 
ILE O    O N N 185 
ILE CB   C N S 186 
ILE CG1  C N N 187 
ILE CG2  C N N 188 
ILE CD1  C N N 189 
ILE OXT  O N N 190 
ILE H    H N N 191 
ILE H2   H N N 192 
ILE HA   H N N 193 
ILE HB   H N N 194 
ILE HG12 H N N 195 
ILE HG13 H N N 196 
ILE HG21 H N N 197 
ILE HG22 H N N 198 
ILE HG23 H N N 199 
ILE HD11 H N N 200 
ILE HD12 H N N 201 
ILE HD13 H N N 202 
ILE HXT  H N N 203 
LEU N    N N N 204 
LEU CA   C N S 205 
LEU C    C N N 206 
LEU O    O N N 207 
LEU CB   C N N 208 
LEU CG   C N N 209 
LEU CD1  C N N 210 
LEU CD2  C N N 211 
LEU OXT  O N N 212 
LEU H    H N N 213 
LEU H2   H N N 214 
LEU HA   H N N 215 
LEU HB2  H N N 216 
LEU HB3  H N N 217 
LEU HG   H N N 218 
LEU HD11 H N N 219 
LEU HD12 H N N 220 
LEU HD13 H N N 221 
LEU HD21 H N N 222 
LEU HD22 H N N 223 
LEU HD23 H N N 224 
LEU HXT  H N N 225 
LYS N    N N N 226 
LYS CA   C N S 227 
LYS C    C N N 228 
LYS O    O N N 229 
LYS CB   C N N 230 
LYS CG   C N N 231 
LYS CD   C N N 232 
LYS CE   C N N 233 
LYS NZ   N N N 234 
LYS OXT  O N N 235 
LYS H    H N N 236 
LYS H2   H N N 237 
LYS HA   H N N 238 
LYS HB2  H N N 239 
LYS HB3  H N N 240 
LYS HG2  H N N 241 
LYS HG3  H N N 242 
LYS HD2  H N N 243 
LYS HD3  H N N 244 
LYS HE2  H N N 245 
LYS HE3  H N N 246 
LYS HZ1  H N N 247 
LYS HZ2  H N N 248 
LYS HZ3  H N N 249 
LYS HXT  H N N 250 
MET N    N N N 251 
MET CA   C N S 252 
MET C    C N N 253 
MET O    O N N 254 
MET CB   C N N 255 
MET CG   C N N 256 
MET SD   S N N 257 
MET CE   C N N 258 
MET OXT  O N N 259 
MET H    H N N 260 
MET H2   H N N 261 
MET HA   H N N 262 
MET HB2  H N N 263 
MET HB3  H N N 264 
MET HG2  H N N 265 
MET HG3  H N N 266 
MET HE1  H N N 267 
MET HE2  H N N 268 
MET HE3  H N N 269 
MET HXT  H N N 270 
NAG C1   C N R 271 
NAG C2   C N R 272 
NAG C3   C N R 273 
NAG C4   C N S 274 
NAG C5   C N R 275 
NAG C6   C N N 276 
NAG C7   C N N 277 
NAG C8   C N N 278 
NAG N2   N N N 279 
NAG O1   O N N 280 
NAG O3   O N N 281 
NAG O4   O N N 282 
NAG O5   O N N 283 
NAG O6   O N N 284 
NAG O7   O N N 285 
NAG H1   H N N 286 
NAG H2   H N N 287 
NAG H3   H N N 288 
NAG H4   H N N 289 
NAG H5   H N N 290 
NAG H61  H N N 291 
NAG H62  H N N 292 
NAG H81  H N N 293 
NAG H82  H N N 294 
NAG H83  H N N 295 
NAG HN2  H N N 296 
NAG HO1  H N N 297 
NAG HO3  H N N 298 
NAG HO4  H N N 299 
NAG HO6  H N N 300 
PHE N    N N N 301 
PHE CA   C N S 302 
PHE C    C N N 303 
PHE O    O N N 304 
PHE CB   C N N 305 
PHE CG   C Y N 306 
PHE CD1  C Y N 307 
PHE CD2  C Y N 308 
PHE CE1  C Y N 309 
PHE CE2  C Y N 310 
PHE CZ   C Y N 311 
PHE OXT  O N N 312 
PHE H    H N N 313 
PHE H2   H N N 314 
PHE HA   H N N 315 
PHE HB2  H N N 316 
PHE HB3  H N N 317 
PHE HD1  H N N 318 
PHE HD2  H N N 319 
PHE HE1  H N N 320 
PHE HE2  H N N 321 
PHE HZ   H N N 322 
PHE HXT  H N N 323 
PRO N    N N N 324 
PRO CA   C N S 325 
PRO C    C N N 326 
PRO O    O N N 327 
PRO CB   C N N 328 
PRO CG   C N N 329 
PRO CD   C N N 330 
PRO OXT  O N N 331 
PRO H    H N N 332 
PRO HA   H N N 333 
PRO HB2  H N N 334 
PRO HB3  H N N 335 
PRO HG2  H N N 336 
PRO HG3  H N N 337 
PRO HD2  H N N 338 
PRO HD3  H N N 339 
PRO HXT  H N N 340 
SER N    N N N 341 
SER CA   C N S 342 
SER C    C N N 343 
SER O    O N N 344 
SER CB   C N N 345 
SER OG   O N N 346 
SER OXT  O N N 347 
SER H    H N N 348 
SER H2   H N N 349 
SER HA   H N N 350 
SER HB2  H N N 351 
SER HB3  H N N 352 
SER HG   H N N 353 
SER HXT  H N N 354 
THR N    N N N 355 
THR CA   C N S 356 
THR C    C N N 357 
THR O    O N N 358 
THR CB   C N R 359 
THR OG1  O N N 360 
THR CG2  C N N 361 
THR OXT  O N N 362 
THR H    H N N 363 
THR H2   H N N 364 
THR HA   H N N 365 
THR HB   H N N 366 
THR HG1  H N N 367 
THR HG21 H N N 368 
THR HG22 H N N 369 
THR HG23 H N N 370 
THR HXT  H N N 371 
TRP N    N N N 372 
TRP CA   C N S 373 
TRP C    C N N 374 
TRP O    O N N 375 
TRP CB   C N N 376 
TRP CG   C Y N 377 
TRP CD1  C Y N 378 
TRP CD2  C Y N 379 
TRP NE1  N Y N 380 
TRP CE2  C Y N 381 
TRP CE3  C Y N 382 
TRP CZ2  C Y N 383 
TRP CZ3  C Y N 384 
TRP CH2  C Y N 385 
TRP OXT  O N N 386 
TRP H    H N N 387 
TRP H2   H N N 388 
TRP HA   H N N 389 
TRP HB2  H N N 390 
TRP HB3  H N N 391 
TRP HD1  H N N 392 
TRP HE1  H N N 393 
TRP HE3  H N N 394 
TRP HZ2  H N N 395 
TRP HZ3  H N N 396 
TRP HH2  H N N 397 
TRP HXT  H N N 398 
TYR N    N N N 399 
TYR CA   C N S 400 
TYR C    C N N 401 
TYR O    O N N 402 
TYR CB   C N N 403 
TYR CG   C Y N 404 
TYR CD1  C Y N 405 
TYR CD2  C Y N 406 
TYR CE1  C Y N 407 
TYR CE2  C Y N 408 
TYR CZ   C Y N 409 
TYR OH   O N N 410 
TYR OXT  O N N 411 
TYR H    H N N 412 
TYR H2   H N N 413 
TYR HA   H N N 414 
TYR HB2  H N N 415 
TYR HB3  H N N 416 
TYR HD1  H N N 417 
TYR HD2  H N N 418 
TYR HE1  H N N 419 
TYR HE2  H N N 420 
TYR HH   H N N 421 
TYR HXT  H N N 422 
VAL N    N N N 423 
VAL CA   C N S 424 
VAL C    C N N 425 
VAL O    O N N 426 
VAL CB   C N N 427 
VAL CG1  C N N 428 
VAL CG2  C N N 429 
VAL OXT  O N N 430 
VAL H    H N N 431 
VAL H2   H N N 432 
VAL HA   H N N 433 
VAL HB   H N N 434 
VAL HG11 H N N 435 
VAL HG12 H N N 436 
VAL HG13 H N N 437 
VAL HG21 H N N 438 
VAL HG22 H N N 439 
VAL HG23 H N N 440 
VAL HXT  H N N 441 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ACT C   O    doub N N 1   
ACT C   OXT  sing N N 2   
ACT C   CH3  sing N N 3   
ACT CH3 H1   sing N N 4   
ACT CH3 H2   sing N N 5   
ACT CH3 H3   sing N N 6   
ALA N   CA   sing N N 7   
ALA N   H    sing N N 8   
ALA N   H2   sing N N 9   
ALA CA  C    sing N N 10  
ALA CA  CB   sing N N 11  
ALA CA  HA   sing N N 12  
ALA C   O    doub N N 13  
ALA C   OXT  sing N N 14  
ALA CB  HB1  sing N N 15  
ALA CB  HB2  sing N N 16  
ALA CB  HB3  sing N N 17  
ALA OXT HXT  sing N N 18  
ARG N   CA   sing N N 19  
ARG N   H    sing N N 20  
ARG N   H2   sing N N 21  
ARG CA  C    sing N N 22  
ARG CA  CB   sing N N 23  
ARG CA  HA   sing N N 24  
ARG C   O    doub N N 25  
ARG C   OXT  sing N N 26  
ARG CB  CG   sing N N 27  
ARG CB  HB2  sing N N 28  
ARG CB  HB3  sing N N 29  
ARG CG  CD   sing N N 30  
ARG CG  HG2  sing N N 31  
ARG CG  HG3  sing N N 32  
ARG CD  NE   sing N N 33  
ARG CD  HD2  sing N N 34  
ARG CD  HD3  sing N N 35  
ARG NE  CZ   sing N N 36  
ARG NE  HE   sing N N 37  
ARG CZ  NH1  sing N N 38  
ARG CZ  NH2  doub N N 39  
ARG NH1 HH11 sing N N 40  
ARG NH1 HH12 sing N N 41  
ARG NH2 HH21 sing N N 42  
ARG NH2 HH22 sing N N 43  
ARG OXT HXT  sing N N 44  
ASN N   CA   sing N N 45  
ASN N   H    sing N N 46  
ASN N   H2   sing N N 47  
ASN CA  C    sing N N 48  
ASN CA  CB   sing N N 49  
ASN CA  HA   sing N N 50  
ASN C   O    doub N N 51  
ASN C   OXT  sing N N 52  
ASN CB  CG   sing N N 53  
ASN CB  HB2  sing N N 54  
ASN CB  HB3  sing N N 55  
ASN CG  OD1  doub N N 56  
ASN CG  ND2  sing N N 57  
ASN ND2 HD21 sing N N 58  
ASN ND2 HD22 sing N N 59  
ASN OXT HXT  sing N N 60  
ASP N   CA   sing N N 61  
ASP N   H    sing N N 62  
ASP N   H2   sing N N 63  
ASP CA  C    sing N N 64  
ASP CA  CB   sing N N 65  
ASP CA  HA   sing N N 66  
ASP C   O    doub N N 67  
ASP C   OXT  sing N N 68  
ASP CB  CG   sing N N 69  
ASP CB  HB2  sing N N 70  
ASP CB  HB3  sing N N 71  
ASP CG  OD1  doub N N 72  
ASP CG  OD2  sing N N 73  
ASP OD2 HD2  sing N N 74  
ASP OXT HXT  sing N N 75  
CYS N   CA   sing N N 76  
CYS N   H    sing N N 77  
CYS N   H2   sing N N 78  
CYS CA  C    sing N N 79  
CYS CA  CB   sing N N 80  
CYS CA  HA   sing N N 81  
CYS C   O    doub N N 82  
CYS C   OXT  sing N N 83  
CYS CB  SG   sing N N 84  
CYS CB  HB2  sing N N 85  
CYS CB  HB3  sing N N 86  
CYS SG  HG   sing N N 87  
CYS OXT HXT  sing N N 88  
GLN N   CA   sing N N 89  
GLN N   H    sing N N 90  
GLN N   H2   sing N N 91  
GLN CA  C    sing N N 92  
GLN CA  CB   sing N N 93  
GLN CA  HA   sing N N 94  
GLN C   O    doub N N 95  
GLN C   OXT  sing N N 96  
GLN CB  CG   sing N N 97  
GLN CB  HB2  sing N N 98  
GLN CB  HB3  sing N N 99  
GLN CG  CD   sing N N 100 
GLN CG  HG2  sing N N 101 
GLN CG  HG3  sing N N 102 
GLN CD  OE1  doub N N 103 
GLN CD  NE2  sing N N 104 
GLN NE2 HE21 sing N N 105 
GLN NE2 HE22 sing N N 106 
GLN OXT HXT  sing N N 107 
GLU N   CA   sing N N 108 
GLU N   H    sing N N 109 
GLU N   H2   sing N N 110 
GLU CA  C    sing N N 111 
GLU CA  CB   sing N N 112 
GLU CA  HA   sing N N 113 
GLU C   O    doub N N 114 
GLU C   OXT  sing N N 115 
GLU CB  CG   sing N N 116 
GLU CB  HB2  sing N N 117 
GLU CB  HB3  sing N N 118 
GLU CG  CD   sing N N 119 
GLU CG  HG2  sing N N 120 
GLU CG  HG3  sing N N 121 
GLU CD  OE1  doub N N 122 
GLU CD  OE2  sing N N 123 
GLU OE2 HE2  sing N N 124 
GLU OXT HXT  sing N N 125 
GLY N   CA   sing N N 126 
GLY N   H    sing N N 127 
GLY N   H2   sing N N 128 
GLY CA  C    sing N N 129 
GLY CA  HA2  sing N N 130 
GLY CA  HA3  sing N N 131 
GLY C   O    doub N N 132 
GLY C   OXT  sing N N 133 
GLY OXT HXT  sing N N 134 
GOL C1  O1   sing N N 135 
GOL C1  C2   sing N N 136 
GOL C1  H11  sing N N 137 
GOL C1  H12  sing N N 138 
GOL O1  HO1  sing N N 139 
GOL C2  O2   sing N N 140 
GOL C2  C3   sing N N 141 
GOL C2  H2   sing N N 142 
GOL O2  HO2  sing N N 143 
GOL C3  O3   sing N N 144 
GOL C3  H31  sing N N 145 
GOL C3  H32  sing N N 146 
GOL O3  HO3  sing N N 147 
HIS N   CA   sing N N 148 
HIS N   H    sing N N 149 
HIS N   H2   sing N N 150 
HIS CA  C    sing N N 151 
HIS CA  CB   sing N N 152 
HIS CA  HA   sing N N 153 
HIS C   O    doub N N 154 
HIS C   OXT  sing N N 155 
HIS CB  CG   sing N N 156 
HIS CB  HB2  sing N N 157 
HIS CB  HB3  sing N N 158 
HIS CG  ND1  sing Y N 159 
HIS CG  CD2  doub Y N 160 
HIS ND1 CE1  doub Y N 161 
HIS ND1 HD1  sing N N 162 
HIS CD2 NE2  sing Y N 163 
HIS CD2 HD2  sing N N 164 
HIS CE1 NE2  sing Y N 165 
HIS CE1 HE1  sing N N 166 
HIS NE2 HE2  sing N N 167 
HIS OXT HXT  sing N N 168 
HOH O   H1   sing N N 169 
HOH O   H2   sing N N 170 
ILE N   CA   sing N N 171 
ILE N   H    sing N N 172 
ILE N   H2   sing N N 173 
ILE CA  C    sing N N 174 
ILE CA  CB   sing N N 175 
ILE CA  HA   sing N N 176 
ILE C   O    doub N N 177 
ILE C   OXT  sing N N 178 
ILE CB  CG1  sing N N 179 
ILE CB  CG2  sing N N 180 
ILE CB  HB   sing N N 181 
ILE CG1 CD1  sing N N 182 
ILE CG1 HG12 sing N N 183 
ILE CG1 HG13 sing N N 184 
ILE CG2 HG21 sing N N 185 
ILE CG2 HG22 sing N N 186 
ILE CG2 HG23 sing N N 187 
ILE CD1 HD11 sing N N 188 
ILE CD1 HD12 sing N N 189 
ILE CD1 HD13 sing N N 190 
ILE OXT HXT  sing N N 191 
LEU N   CA   sing N N 192 
LEU N   H    sing N N 193 
LEU N   H2   sing N N 194 
LEU CA  C    sing N N 195 
LEU CA  CB   sing N N 196 
LEU CA  HA   sing N N 197 
LEU C   O    doub N N 198 
LEU C   OXT  sing N N 199 
LEU CB  CG   sing N N 200 
LEU CB  HB2  sing N N 201 
LEU CB  HB3  sing N N 202 
LEU CG  CD1  sing N N 203 
LEU CG  CD2  sing N N 204 
LEU CG  HG   sing N N 205 
LEU CD1 HD11 sing N N 206 
LEU CD1 HD12 sing N N 207 
LEU CD1 HD13 sing N N 208 
LEU CD2 HD21 sing N N 209 
LEU CD2 HD22 sing N N 210 
LEU CD2 HD23 sing N N 211 
LEU OXT HXT  sing N N 212 
LYS N   CA   sing N N 213 
LYS N   H    sing N N 214 
LYS N   H2   sing N N 215 
LYS CA  C    sing N N 216 
LYS CA  CB   sing N N 217 
LYS CA  HA   sing N N 218 
LYS C   O    doub N N 219 
LYS C   OXT  sing N N 220 
LYS CB  CG   sing N N 221 
LYS CB  HB2  sing N N 222 
LYS CB  HB3  sing N N 223 
LYS CG  CD   sing N N 224 
LYS CG  HG2  sing N N 225 
LYS CG  HG3  sing N N 226 
LYS CD  CE   sing N N 227 
LYS CD  HD2  sing N N 228 
LYS CD  HD3  sing N N 229 
LYS CE  NZ   sing N N 230 
LYS CE  HE2  sing N N 231 
LYS CE  HE3  sing N N 232 
LYS NZ  HZ1  sing N N 233 
LYS NZ  HZ2  sing N N 234 
LYS NZ  HZ3  sing N N 235 
LYS OXT HXT  sing N N 236 
MET N   CA   sing N N 237 
MET N   H    sing N N 238 
MET N   H2   sing N N 239 
MET CA  C    sing N N 240 
MET CA  CB   sing N N 241 
MET CA  HA   sing N N 242 
MET C   O    doub N N 243 
MET C   OXT  sing N N 244 
MET CB  CG   sing N N 245 
MET CB  HB2  sing N N 246 
MET CB  HB3  sing N N 247 
MET CG  SD   sing N N 248 
MET CG  HG2  sing N N 249 
MET CG  HG3  sing N N 250 
MET SD  CE   sing N N 251 
MET CE  HE1  sing N N 252 
MET CE  HE2  sing N N 253 
MET CE  HE3  sing N N 254 
MET OXT HXT  sing N N 255 
NAG C1  C2   sing N N 256 
NAG C1  O1   sing N N 257 
NAG C1  O5   sing N N 258 
NAG C1  H1   sing N N 259 
NAG C2  C3   sing N N 260 
NAG C2  N2   sing N N 261 
NAG C2  H2   sing N N 262 
NAG C3  C4   sing N N 263 
NAG C3  O3   sing N N 264 
NAG C3  H3   sing N N 265 
NAG C4  C5   sing N N 266 
NAG C4  O4   sing N N 267 
NAG C4  H4   sing N N 268 
NAG C5  C6   sing N N 269 
NAG C5  O5   sing N N 270 
NAG C5  H5   sing N N 271 
NAG C6  O6   sing N N 272 
NAG C6  H61  sing N N 273 
NAG C6  H62  sing N N 274 
NAG C7  C8   sing N N 275 
NAG C7  N2   sing N N 276 
NAG C7  O7   doub N N 277 
NAG C8  H81  sing N N 278 
NAG C8  H82  sing N N 279 
NAG C8  H83  sing N N 280 
NAG N2  HN2  sing N N 281 
NAG O1  HO1  sing N N 282 
NAG O3  HO3  sing N N 283 
NAG O4  HO4  sing N N 284 
NAG O6  HO6  sing N N 285 
PHE N   CA   sing N N 286 
PHE N   H    sing N N 287 
PHE N   H2   sing N N 288 
PHE CA  C    sing N N 289 
PHE CA  CB   sing N N 290 
PHE CA  HA   sing N N 291 
PHE C   O    doub N N 292 
PHE C   OXT  sing N N 293 
PHE CB  CG   sing N N 294 
PHE CB  HB2  sing N N 295 
PHE CB  HB3  sing N N 296 
PHE CG  CD1  doub Y N 297 
PHE CG  CD2  sing Y N 298 
PHE CD1 CE1  sing Y N 299 
PHE CD1 HD1  sing N N 300 
PHE CD2 CE2  doub Y N 301 
PHE CD2 HD2  sing N N 302 
PHE CE1 CZ   doub Y N 303 
PHE CE1 HE1  sing N N 304 
PHE CE2 CZ   sing Y N 305 
PHE CE2 HE2  sing N N 306 
PHE CZ  HZ   sing N N 307 
PHE OXT HXT  sing N N 308 
PRO N   CA   sing N N 309 
PRO N   CD   sing N N 310 
PRO N   H    sing N N 311 
PRO CA  C    sing N N 312 
PRO CA  CB   sing N N 313 
PRO CA  HA   sing N N 314 
PRO C   O    doub N N 315 
PRO C   OXT  sing N N 316 
PRO CB  CG   sing N N 317 
PRO CB  HB2  sing N N 318 
PRO CB  HB3  sing N N 319 
PRO CG  CD   sing N N 320 
PRO CG  HG2  sing N N 321 
PRO CG  HG3  sing N N 322 
PRO CD  HD2  sing N N 323 
PRO CD  HD3  sing N N 324 
PRO OXT HXT  sing N N 325 
SER N   CA   sing N N 326 
SER N   H    sing N N 327 
SER N   H2   sing N N 328 
SER CA  C    sing N N 329 
SER CA  CB   sing N N 330 
SER CA  HA   sing N N 331 
SER C   O    doub N N 332 
SER C   OXT  sing N N 333 
SER CB  OG   sing N N 334 
SER CB  HB2  sing N N 335 
SER CB  HB3  sing N N 336 
SER OG  HG   sing N N 337 
SER OXT HXT  sing N N 338 
THR N   CA   sing N N 339 
THR N   H    sing N N 340 
THR N   H2   sing N N 341 
THR CA  C    sing N N 342 
THR CA  CB   sing N N 343 
THR CA  HA   sing N N 344 
THR C   O    doub N N 345 
THR C   OXT  sing N N 346 
THR CB  OG1  sing N N 347 
THR CB  CG2  sing N N 348 
THR CB  HB   sing N N 349 
THR OG1 HG1  sing N N 350 
THR CG2 HG21 sing N N 351 
THR CG2 HG22 sing N N 352 
THR CG2 HG23 sing N N 353 
THR OXT HXT  sing N N 354 
TRP N   CA   sing N N 355 
TRP N   H    sing N N 356 
TRP N   H2   sing N N 357 
TRP CA  C    sing N N 358 
TRP CA  CB   sing N N 359 
TRP CA  HA   sing N N 360 
TRP C   O    doub N N 361 
TRP C   OXT  sing N N 362 
TRP CB  CG   sing N N 363 
TRP CB  HB2  sing N N 364 
TRP CB  HB3  sing N N 365 
TRP CG  CD1  doub Y N 366 
TRP CG  CD2  sing Y N 367 
TRP CD1 NE1  sing Y N 368 
TRP CD1 HD1  sing N N 369 
TRP CD2 CE2  doub Y N 370 
TRP CD2 CE3  sing Y N 371 
TRP NE1 CE2  sing Y N 372 
TRP NE1 HE1  sing N N 373 
TRP CE2 CZ2  sing Y N 374 
TRP CE3 CZ3  doub Y N 375 
TRP CE3 HE3  sing N N 376 
TRP CZ2 CH2  doub Y N 377 
TRP CZ2 HZ2  sing N N 378 
TRP CZ3 CH2  sing Y N 379 
TRP CZ3 HZ3  sing N N 380 
TRP CH2 HH2  sing N N 381 
TRP OXT HXT  sing N N 382 
TYR N   CA   sing N N 383 
TYR N   H    sing N N 384 
TYR N   H2   sing N N 385 
TYR CA  C    sing N N 386 
TYR CA  CB   sing N N 387 
TYR CA  HA   sing N N 388 
TYR C   O    doub N N 389 
TYR C   OXT  sing N N 390 
TYR CB  CG   sing N N 391 
TYR CB  HB2  sing N N 392 
TYR CB  HB3  sing N N 393 
TYR CG  CD1  doub Y N 394 
TYR CG  CD2  sing Y N 395 
TYR CD1 CE1  sing Y N 396 
TYR CD1 HD1  sing N N 397 
TYR CD2 CE2  doub Y N 398 
TYR CD2 HD2  sing N N 399 
TYR CE1 CZ   doub Y N 400 
TYR CE1 HE1  sing N N 401 
TYR CE2 CZ   sing Y N 402 
TYR CE2 HE2  sing N N 403 
TYR CZ  OH   sing N N 404 
TYR OH  HH   sing N N 405 
TYR OXT HXT  sing N N 406 
VAL N   CA   sing N N 407 
VAL N   H    sing N N 408 
VAL N   H2   sing N N 409 
VAL CA  C    sing N N 410 
VAL CA  CB   sing N N 411 
VAL CA  HA   sing N N 412 
VAL C   O    doub N N 413 
VAL C   OXT  sing N N 414 
VAL CB  CG1  sing N N 415 
VAL CB  CG2  sing N N 416 
VAL CB  HB   sing N N 417 
VAL CG1 HG11 sing N N 418 
VAL CG1 HG12 sing N N 419 
VAL CG1 HG13 sing N N 420 
VAL CG2 HG21 sing N N 421 
VAL CG2 HG22 sing N N 422 
VAL CG2 HG23 sing N N 423 
VAL OXT HXT  sing N N 424 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
6 NAG 1 n 
6 NAG 2 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6V1A 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'I 1 2 1' 
_space_group.name_Hall        'C 2y (x,y,-x+z)' 
_space_group.IT_number        5 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9EJI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009819 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003176 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012221 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007341 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ILE A 1  3   ? 1.94321   -15.61776 30.63143  1.000 49.82173 ? 0   ILE A N   1 
ATOM   2    C CA  . ILE A 1  3   ? 0.85288   -14.88873 29.99530  1.000 50.90054 ? 0   ILE A CA  1 
ATOM   3    C C   . ILE A 1  3   ? 1.17108   -14.65407 28.52110  1.000 40.69368 ? 0   ILE A C   1 
ATOM   4    O O   . ILE A 1  3   ? 2.27338   -14.22927 28.17525  1.000 45.59881 ? 0   ILE A O   1 
ATOM   5    C CB  . ILE A 1  3   ? 0.57715   -13.55790 30.72087  1.000 39.44065 ? 0   ILE A CB  1 
ATOM   6    C CG1 . ILE A 1  3   ? 0.20675   -13.81529 32.18318  1.000 38.46189 ? 0   ILE A CG1 1 
ATOM   7    C CG2 . ILE A 1  3   ? -0.52886  -12.78187 30.01933  1.000 35.65951 ? 0   ILE A CG2 1 
ATOM   8    C CD1 . ILE A 1  3   ? -0.08801  -12.55772 32.97049  1.000 28.98922 ? 0   ILE A CD1 1 
ATOM   9    N N   . VAL A 1  4   ? 0.19928   -14.93633 27.65644  1.000 38.31999 ? 1   VAL A N   1 
ATOM   10   C CA  . VAL A 1  4   ? 0.35064   -14.78888 26.21297  1.000 37.84439 ? 1   VAL A CA  1 
ATOM   11   C C   . VAL A 1  4   ? -0.29149  -13.47688 25.78599  1.000 33.93020 ? 1   VAL A C   1 
ATOM   12   O O   . VAL A 1  4   ? -1.45985  -13.21651 26.10058  1.000 43.58404 ? 1   VAL A O   1 
ATOM   13   C CB  . VAL A 1  4   ? -0.27516  -15.97827 25.46453  1.000 39.74591 ? 1   VAL A CB  1 
ATOM   14   C CG1 . VAL A 1  4   ? -0.24384  -15.74035 23.96006  1.000 35.71702 ? 1   VAL A CG1 1 
ATOM   15   C CG2 . VAL A 1  4   ? 0.44711   -17.26819 25.82376  1.000 38.37014 ? 1   VAL A CG2 1 
ATOM   16   N N   . ALA A 1  5   ? 0.46855   -12.65146 25.06946  1.000 29.70589 ? 2   ALA A N   1 
ATOM   17   C CA  . ALA A 1  5   ? -0.02780  -11.36581 24.60052  1.000 28.65325 ? 2   ALA A CA  1 
ATOM   18   C C   . ALA A 1  5   ? 0.76441   -10.95105 23.37021  1.000 30.90460 ? 2   ALA A C   1 
ATOM   19   O O   . ALA A 1  5   ? 1.89029   -11.40603 23.15169  1.000 28.34974 ? 2   ALA A O   1 
ATOM   20   C CB  . ALA A 1  5   ? 0.06829   -10.29303 25.69085  1.000 25.35544 ? 2   ALA A CB  1 
ATOM   21   N N   . ASP A 1  6   ? 0.15402   -10.07820 22.56367  1.000 28.06726 ? 3   ASP A N   1 
ATOM   22   C CA  . ASP A 1  6   ? 0.84395   -9.55485  21.38830  1.000 27.50948 ? 3   ASP A CA  1 
ATOM   23   C C   . ASP A 1  6   ? 1.91154   -8.54128  21.78225  1.000 27.52484 ? 3   ASP A C   1 
ATOM   24   O O   . ASP A 1  6   ? 3.00413   -8.52631  21.20505  1.000 26.19537 ? 3   ASP A O   1 
ATOM   25   C CB  . ASP A 1  6   ? -0.15896  -8.92255  20.42411  1.000 26.84610 ? 3   ASP A CB  1 
ATOM   26   C CG  . ASP A 1  6   ? -1.11760  -9.93543  19.82716  1.000 32.86614 ? 3   ASP A CG  1 
ATOM   27   O OD1 . ASP A 1  6   ? -0.79791  -11.14245 19.83432  1.000 34.71784 ? 3   ASP A OD1 1 
ATOM   28   O OD2 . ASP A 1  6   ? -2.19402  -9.52116  19.34889  1.000 37.35008 ? 3   ASP A OD2 1 
ATOM   29   N N   . HIS A 1  7   ? 1.61157   -7.68344  22.75578  1.000 25.42063 ? 4   HIS A N   1 
ATOM   30   C CA  . HIS A 1  7   ? 2.54902   -6.68633  23.24980  1.000 25.36185 ? 4   HIS A CA  1 
ATOM   31   C C   . HIS A 1  7   ? 2.55300   -6.70752  24.77058  1.000 28.02312 ? 4   HIS A C   1 
ATOM   32   O O   . HIS A 1  7   ? 1.50627   -6.88975  25.39963  1.000 21.76468 ? 4   HIS A O   1 
ATOM   33   C CB  . HIS A 1  7   ? 2.19214   -5.27694  22.75372  1.000 24.13901 ? 4   HIS A CB  1 
ATOM   34   C CG  . HIS A 1  7   ? 2.11674   -5.15795  21.26375  1.000 28.79189 ? 4   HIS A CG  1 
ATOM   35   N ND1 . HIS A 1  7   ? 3.23521   -5.16902  20.45802  1.000 29.54278 ? 4   HIS A ND1 1 
ATOM   36   C CD2 . HIS A 1  7   ? 1.05620   -5.01773  20.43312  1.000 23.53592 ? 4   HIS A CD2 1 
ATOM   37   C CE1 . HIS A 1  7   ? 2.86671   -5.04476  19.19516  1.000 28.13032 ? 4   HIS A CE1 1 
ATOM   38   N NE2 . HIS A 1  7   ? 1.54968   -4.95107  19.15269  1.000 29.63734 ? 4   HIS A NE2 1 
ATOM   39   N N   . VAL A 1  8   ? 3.73471   -6.52623  25.35692  1.000 23.28347 ? 5   VAL A N   1 
ATOM   40   C CA  . VAL A 1  8   ? 3.89738   -6.44071  26.80332  1.000 20.90165 ? 5   VAL A CA  1 
ATOM   41   C C   . VAL A 1  8   ? 4.69033   -5.18239  27.11943  1.000 26.18378 ? 5   VAL A C   1 
ATOM   42   O O   . VAL A 1  8   ? 5.75440   -4.94991  26.53404  1.000 24.32368 ? 5   VAL A O   1 
ATOM   43   C CB  . VAL A 1  8   ? 4.60568   -7.67921  27.38682  1.000 27.76866 ? 5   VAL A CB  1 
ATOM   44   C CG1 . VAL A 1  8   ? 4.61627   -7.60999  28.90907  1.000 22.76891 ? 5   VAL A CG1 1 
ATOM   45   C CG2 . VAL A 1  8   ? 3.93340   -8.95915  26.91320  1.000 30.27915 ? 5   VAL A CG2 1 
ATOM   46   N N   . ALA A 1  9   ? 4.18087   -4.37929  28.04841  1.000 23.92661 ? 6   ALA A N   1 
ATOM   47   C CA  . ALA A 1  9   ? 4.83922   -3.14835  28.45201  1.000 23.88510 ? 6   ALA A CA  1 
ATOM   48   C C   . ALA A 1  9   ? 4.97335   -3.10032  29.96611  1.000 26.45517 ? 6   ALA A C   1 
ATOM   49   O O   . ALA A 1  9   ? 4.19325   -3.71653  30.69760  1.000 24.78668 ? 6   ALA A O   1 
ATOM   50   C CB  . ALA A 1  9   ? 4.07250   -1.91700  27.96017  1.000 20.43625 ? 6   ALA A CB  1 
ATOM   51   N N   . SER A 1  10  ? 5.97900   -2.36130  30.42755  1.000 20.72174 ? 7   SER A N   1 
ATOM   52   C CA  . SER A 1  10  ? 6.17782   -2.07951  31.84520  1.000 23.49021 ? 7   SER A CA  1 
ATOM   53   C C   . SER A 1  10  ? 6.16292   -0.56828  32.02616  1.000 24.74176 ? 7   SER A C   1 
ATOM   54   O O   . SER A 1  10  ? 7.10559   0.11776   31.61536  1.000 22.79587 ? 7   SER A O   1 
ATOM   55   C CB  . SER A 1  10  ? 7.48957   -2.67652  32.35552  1.000 24.95701 ? 7   SER A CB  1 
ATOM   56   O OG  . SER A 1  10  ? 7.39303   -4.07783  32.54044  1.000 27.00604 ? 7   SER A OG  1 
ATOM   57   N N   . TYR A 1  11  ? 5.09964   -0.05132  32.64014  1.000 19.52131 ? 8   TYR A N   1 
ATOM   58   C CA  . TYR A 1  11  ? 4.97149   1.37053   32.96625  1.000 22.46381 ? 8   TYR A CA  1 
ATOM   59   C C   . TYR A 1  11  ? 4.83704   1.51381   34.48288  1.000 25.84063 ? 8   TYR A C   1 
ATOM   60   O O   . TYR A 1  11  ? 3.74022   1.75931   34.98928  1.000 25.18833 ? 8   TYR A O   1 
ATOM   61   C CB  . TYR A 1  11  ? 3.75493   2.01291   32.25355  1.000 24.51847 ? 8   TYR A CB  1 
ATOM   62   C CG  . TYR A 1  11  ? 3.63533   1.77409   30.76311  1.000 30.21650 ? 8   TYR A CG  1 
ATOM   63   C CD1 . TYR A 1  11  ? 4.68399   2.06363   29.89887  1.000 24.47622 ? 8   TYR A CD1 1 
ATOM   64   C CD2 . TYR A 1  11  ? 2.45015   1.29613   30.21730  1.000 25.97739 ? 8   TYR A CD2 1 
ATOM   65   C CE1 . TYR A 1  11  ? 4.56009   1.86052   28.53395  1.000 27.76622 ? 8   TYR A CE1 1 
ATOM   66   C CE2 . TYR A 1  11  ? 2.31709   1.09092   28.85806  1.000 26.05946 ? 8   TYR A CE2 1 
ATOM   67   C CZ  . TYR A 1  11  ? 3.37311   1.37628   28.02114  1.000 26.04830 ? 8   TYR A CZ  1 
ATOM   68   O OH  . TYR A 1  11  ? 3.23864   1.17026   26.66819  1.000 27.68686 ? 8   TYR A OH  1 
ATOM   69   N N   . GLY A 1  12  ? 5.94536   1.37655   35.20934  1.000 24.30658 ? 9   GLY A N   1 
ATOM   70   C CA  . GLY A 1  12  ? 7.24952   1.06642   34.65454  1.000 25.85238 ? 9   GLY A CA  1 
ATOM   71   C C   . GLY A 1  12  ? 7.93959   -0.00500  35.47534  1.000 25.98765 ? 9   GLY A C   1 
ATOM   72   O O   . GLY A 1  12  ? 7.28445   -0.74409  36.21124  1.000 24.66583 ? 9   GLY A O   1 
ATOM   73   N N   . VAL A 1  13  ? 9.25931   -0.09660  35.35094  1.000 22.62405 ? 10  VAL A N   1 
ATOM   74   C CA  . VAL A 1  13  ? 10.06575  -0.99753  36.16597  1.000 23.17929 ? 10  VAL A CA  1 
ATOM   75   C C   . VAL A 1  13  ? 10.69077  -0.16854  37.27944  1.000 28.76947 ? 10  VAL A C   1 
ATOM   76   O O   . VAL A 1  13  ? 11.52551  0.70597   37.02306  1.000 26.55651 ? 10  VAL A O   1 
ATOM   77   C CB  . VAL A 1  13  ? 11.13905  -1.71584  35.33854  1.000 22.44411 ? 10  VAL A CB  1 
ATOM   78   C CG1 . VAL A 1  13  ? 11.99536  -2.59011  36.24085  1.000 16.89879 ? 10  VAL A CG1 1 
ATOM   79   C CG2 . VAL A 1  13  ? 10.49909  -2.55008  34.24108  1.000 19.75310 ? 10  VAL A CG2 1 
ATOM   80   N N   . ASN A 1  14  ? 10.28576  -0.43952  38.51608  1.000 26.45788 ? 11  ASN A N   1 
ATOM   81   C CA  . ASN A 1  14  ? 10.78198  0.26366   39.69053  1.000 24.21149 ? 11  ASN A CA  1 
ATOM   82   C C   . ASN A 1  14  ? 11.69002  -0.66904  40.47867  1.000 23.50047 ? 11  ASN A C   1 
ATOM   83   O O   . ASN A 1  14  ? 11.32127  -1.81578  40.75148  1.000 26.01813 ? 11  ASN A O   1 
ATOM   84   C CB  . ASN A 1  14  ? 9.62655   0.74944   40.57124  1.000 27.09730 ? 11  ASN A CB  1 
ATOM   85   C CG  . ASN A 1  14  ? 8.74536   1.77389   39.87638  1.000 29.27169 ? 11  ASN A CG  1 
ATOM   86   O OD1 . ASN A 1  14  ? 8.77103   2.95883   40.21184  1.000 25.87625 ? 11  ASN A OD1 1 
ATOM   87   N ND2 . ASN A 1  14  ? 7.95070   1.31960   38.91253  1.000 24.85460 ? 11  ASN A ND2 1 
ATOM   88   N N   . LEU A 1  15  ? 12.87006  -0.17813  40.84498  1.000 23.78112 ? 12  LEU A N   1 
ATOM   89   C CA  . LEU A 1  15  ? 13.85673  -0.99081  41.53981  1.000 26.50945 ? 12  LEU A CA  1 
ATOM   90   C C   . LEU A 1  15  ? 14.51120  -0.16928  42.63948  1.000 24.00348 ? 12  LEU A C   1 
ATOM   91   O O   . LEU A 1  15  ? 14.83148  1.00492   42.43938  1.000 29.98409 ? 12  LEU A O   1 
ATOM   92   C CB  . LEU A 1  15  ? 14.91781  -1.51993  40.56221  1.000 21.65340 ? 12  LEU A CB  1 
ATOM   93   C CG  . LEU A 1  15  ? 16.21465  -2.08858  41.13665  1.000 29.04897 ? 12  LEU A CG  1 
ATOM   94   C CD1 . LEU A 1  15  ? 15.96777  -3.45793  41.73944  1.000 28.33597 ? 12  LEU A CD1 1 
ATOM   95   C CD2 . LEU A 1  15  ? 17.28647  -2.16169  40.05750  1.000 27.90988 ? 12  LEU A CD2 1 
ATOM   96   N N   . TYR A 1  16  ? 14.69150  -0.78993  43.80355  1.000 27.36354 ? 13  TYR A N   1 
ATOM   97   C CA  . TYR A 1  16  ? 15.41883  -0.18540  44.91044  1.000 24.37650 ? 13  TYR A CA  1 
ATOM   98   C C   . TYR A 1  16  ? 16.07901  -1.29778  45.70940  1.000 27.78765 ? 13  TYR A C   1 
ATOM   99   O O   . TYR A 1  16  ? 15.44756  -2.31748  45.99820  1.000 25.97475 ? 13  TYR A O   1 
ATOM   100  C CB  . TYR A 1  16  ? 14.50264  0.64469   45.81974  1.000 28.10177 ? 13  TYR A CB  1 
ATOM   101  C CG  . TYR A 1  16  ? 15.24544  1.35582   46.93445  1.000 38.86022 ? 13  TYR A CG  1 
ATOM   102  C CD1 . TYR A 1  16  ? 15.36274  0.78274   48.19697  1.000 38.49768 ? 13  TYR A CD1 1 
ATOM   103  C CD2 . TYR A 1  16  ? 15.83317  2.59679   46.72295  1.000 34.70311 ? 13  TYR A CD2 1 
ATOM   104  C CE1 . TYR A 1  16  ? 16.04380  1.42670   49.21608  1.000 33.70142 ? 13  TYR A CE1 1 
ATOM   105  C CE2 . TYR A 1  16  ? 16.51462  3.24864   47.73600  1.000 41.11128 ? 13  TYR A CE2 1 
ATOM   106  C CZ  . TYR A 1  16  ? 16.61631  2.65984   48.97984  1.000 41.97226 ? 13  TYR A CZ  1 
ATOM   107  O OH  . TYR A 1  16  ? 17.29423  3.30828   49.98755  1.000 40.64385 ? 13  TYR A OH  1 
ATOM   108  N N   . GLN A 1  17  ? 17.34622  -1.09828  46.06553  1.000 30.58968 ? 14  GLN A N   1 
ATOM   109  C CA  . GLN A 1  17  ? 18.10084  -2.11516  46.78181  1.000 31.14573 ? 14  GLN A CA  1 
ATOM   110  C C   . GLN A 1  17  ? 18.93787  -1.46774  47.87680  1.000 33.16336 ? 14  GLN A C   1 
ATOM   111  O O   . GLN A 1  17  ? 19.21105  -0.26523  47.85465  1.000 33.97109 ? 14  GLN A O   1 
ATOM   112  C CB  . GLN A 1  17  ? 18.99264  -2.92682  45.83343  1.000 24.73263 ? 14  GLN A CB  1 
ATOM   113  C CG  . GLN A 1  17  ? 19.97407  -2.09591  45.03068  1.000 29.46848 ? 14  GLN A CG  1 
ATOM   114  C CD  . GLN A 1  17  ? 20.58705  -2.87605  43.88280  1.000 34.03831 ? 14  GLN A CD  1 
ATOM   115  O OE1 . GLN A 1  17  ? 20.93797  -4.04612  44.03280  1.000 26.08439 ? 14  GLN A OE1 1 
ATOM   116  N NE2 . GLN A 1  17  ? 20.71653  -2.23152  42.72766  1.000 30.81754 ? 14  GLN A NE2 1 
ATOM   117  N N   . SER A 1  18  ? 19.35050  -2.29680  48.83937  1.000 35.87567 ? 15  SER A N   1 
ATOM   118  C CA  . SER A 1  18  ? 20.06641  -1.80533  50.01211  1.000 36.10021 ? 15  SER A CA  1 
ATOM   119  C C   . SER A 1  18  ? 21.54021  -1.53325  49.73214  1.000 39.29249 ? 15  SER A C   1 
ATOM   120  O O   . SER A 1  18  ? 22.11502  -0.61800  50.33247  1.000 42.18448 ? 15  SER A O   1 
ATOM   121  C CB  . SER A 1  18  ? 19.92961  -2.80368  51.16383  1.000 25.98996 ? 15  SER A CB  1 
ATOM   122  O OG  . SER A 1  18  ? 20.52854  -4.04583  50.83724  1.000 34.23918 ? 15  SER A OG  1 
ATOM   123  N N   . TYR A 1  19  ? 22.16714  -2.30413  48.84351  1.000 37.38185 ? 16  TYR A N   1 
ATOM   124  C CA  . TYR A 1  19  ? 23.58515  -2.11232  48.55729  1.000 39.77251 ? 16  TYR A CA  1 
ATOM   125  C C   . TYR A 1  19  ? 23.82970  -0.73336  47.96512  1.000 42.45968 ? 16  TYR A C   1 
ATOM   126  O O   . TYR A 1  19  ? 23.34045  -0.42795  46.87248  1.000 44.27765 ? 16  TYR A O   1 
ATOM   127  C CB  . TYR A 1  19  ? 24.09234  -3.18555  47.59705  1.000 34.82567 ? 16  TYR A CB  1 
ATOM   128  C CG  . TYR A 1  19  ? 25.57057  -3.05454  47.30001  1.000 42.94038 ? 16  TYR A CG  1 
ATOM   129  C CD1 . TYR A 1  19  ? 26.52310  -3.46429  48.22379  1.000 43.82392 ? 16  TYR A CD1 1 
ATOM   130  C CD2 . TYR A 1  19  ? 26.01348  -2.49477  46.10713  1.000 39.72735 ? 16  TYR A CD2 1 
ATOM   131  C CE1 . TYR A 1  19  ? 27.87484  -3.33927  47.96113  1.000 46.63415 ? 16  TYR A CE1 1 
ATOM   132  C CE2 . TYR A 1  19  ? 27.36411  -2.36298  45.83732  1.000 41.92103 ? 16  TYR A CE2 1 
ATOM   133  C CZ  . TYR A 1  19  ? 28.28950  -2.78748  46.76812  1.000 37.55574 ? 16  TYR A CZ  1 
ATOM   134  O OH  . TYR A 1  19  ? 29.63486  -2.66005  46.50741  1.000 50.68367 ? 16  TYR A OH  1 
ATOM   135  N N   . GLY A 1  20  ? 24.60716  0.08244   48.68331  1.000 51.11806 ? 17  GLY A N   1 
ATOM   136  C CA  . GLY A 1  20  ? 24.92354  1.43165   48.27500  1.000 45.03811 ? 17  GLY A CA  1 
ATOM   137  C C   . GLY A 1  20  ? 23.69596  2.14407   47.76098  1.000 49.65436 ? 17  GLY A C   1 
ATOM   138  O O   . GLY A 1  20  ? 23.56001  2.38362   46.55709  1.000 60.69494 ? 17  GLY A O   1 
ATOM   139  N N   . PRO A 1  21  ? 22.80587  2.55649   48.68961  1.000 54.91098 ? 18  PRO A N   1 
ATOM   140  C CA  . PRO A 1  21  ? 21.37159  2.69360   48.37114  1.000 43.63497 ? 18  PRO A CA  1 
ATOM   141  C C   . PRO A 1  21  ? 21.07352  3.12499   46.94435  1.000 44.38429 ? 18  PRO A C   1 
ATOM   142  O O   . PRO A 1  21  ? 21.12444  4.31455   46.61871  1.000 56.54369 ? 18  PRO A O   1 
ATOM   143  C CB  . PRO A 1  21  ? 20.88913  3.73921   49.38654  1.000 44.63126 ? 18  PRO A CB  1 
ATOM   144  C CG  . PRO A 1  21  ? 21.86346  3.64533   50.51165  1.000 44.01287 ? 18  PRO A CG  1 
ATOM   145  C CD  . PRO A 1  21  ? 23.18262  3.33520   49.88134  1.000 49.87825 ? 18  PRO A CD  1 
ATOM   146  N N   . SER A 1  22  ? 20.77967  2.15453   46.08090  1.000 39.34671 ? 19  SER A N   1 
ATOM   147  C CA  . SER A 1  22  ? 20.63496  2.39666   44.65373  1.000 38.30427 ? 19  SER A CA  1 
ATOM   148  C C   . SER A 1  22  ? 19.21741  2.09122   44.18832  1.000 34.10320 ? 19  SER A C   1 
ATOM   149  O O   . SER A 1  22  ? 18.53715  1.21236   44.72852  1.000 29.04605 ? 19  SER A O   1 
ATOM   150  C CB  . SER A 1  22  ? 21.63954  1.56178   43.84364  1.000 30.19058 ? 19  SER A CB  1 
ATOM   151  O OG  . SER A 1  22  ? 21.90756  0.32182   44.47480  1.000 52.96887 ? 19  SER A OG  1 
ATOM   152  N N   . GLY A 1  23  ? 18.78355  2.83535   43.16647  1.000 31.64818 ? 20  GLY A N   1 
ATOM   153  C CA  . GLY A 1  23  ? 17.48047  2.62949   42.57575  1.000 28.60607 ? 20  GLY A CA  1 
ATOM   154  C C   . GLY A 1  23  ? 17.53011  2.82451   41.07341  1.000 33.27435 ? 20  GLY A C   1 
ATOM   155  O O   . GLY A 1  23  ? 18.50981  3.33280   40.52153  1.000 25.59874 ? 20  GLY A O   1 
ATOM   156  N N   . GLN A 1  24  ? 16.44832  2.40847   40.41866  1.000 26.90402 ? 21  GLN A N   1 
ATOM   157  C CA  . GLN A 1  24  ? 16.32751  2.53386   38.97395  1.000 24.17587 ? 21  GLN A CA  1 
ATOM   158  C C   . GLN A 1  24  ? 14.85484  2.64521   38.60902  1.000 29.34347 ? 21  GLN A C   1 
ATOM   159  O O   . GLN A 1  24  ? 14.00704  1.98313   39.21429  1.000 25.68981 ? 21  GLN A O   1 
ATOM   160  C CB  . GLN A 1  24  ? 16.96688  1.34095   38.25049  1.000 19.31825 ? 21  GLN A CB  1 
ATOM   161  C CG  . GLN A 1  24  ? 17.17505  1.55834   36.75731  1.000 26.97916 ? 21  GLN A CG  1 
ATOM   162  C CD  . GLN A 1  24  ? 17.50328  0.27462   36.01590  1.000 29.48582 ? 21  GLN A CD  1 
ATOM   163  O OE1 . GLN A 1  24  ? 18.66047  0.00900   35.69164  1.000 31.26807 ? 21  GLN A OE1 1 
ATOM   164  N NE2 . GLN A 1  24  ? 16.48254  -0.53023  35.74620  1.000 25.70841 ? 21  GLN A NE2 1 
ATOM   165  N N   . PHE A 1  25  ? 14.56041  3.49119   37.62276  1.000 27.22727 ? 22  PHE A N   1 
ATOM   166  C CA  . PHE A 1  25  ? 13.20396  3.66846   37.11512  1.000 25.38443 ? 22  PHE A CA  1 
ATOM   167  C C   . PHE A 1  25  ? 13.26150  3.69377   35.59752  1.000 29.02875 ? 22  PHE A C   1 
ATOM   168  O O   . PHE A 1  25  ? 13.98057  4.51404   35.01929  1.000 31.33832 ? 22  PHE A O   1 
ATOM   169  C CB  . PHE A 1  25  ? 12.56848  4.95751   37.64749  1.000 28.49597 ? 22  PHE A CB  1 
ATOM   170  C CG  . PHE A 1  25  ? 11.14835  5.16958   37.19034  1.000 28.95896 ? 22  PHE A CG  1 
ATOM   171  C CD1 . PHE A 1  25  ? 10.87599  5.79623   35.98255  1.000 27.91252 ? 22  PHE A CD1 1 
ATOM   172  C CD2 . PHE A 1  25  ? 10.08657  4.74372   37.97068  1.000 26.30665 ? 22  PHE A CD2 1 
ATOM   173  C CE1 . PHE A 1  25  ? 9.57431   5.98877   35.56214  1.000 29.66150 ? 22  PHE A CE1 1 
ATOM   174  C CE2 . PHE A 1  25  ? 8.78058   4.93606   37.55748  1.000 26.94772 ? 22  PHE A CE2 1 
ATOM   175  C CZ  . PHE A 1  25  ? 8.52389   5.55971   36.35236  1.000 28.86552 ? 22  PHE A CZ  1 
ATOM   176  N N   . THR A 1  26  ? 12.50262  2.80666   34.95644  1.000 27.69867 ? 23  THR A N   1 
ATOM   177  C CA  . THR A 1  26  ? 12.47103  2.71555   33.50414  1.000 22.60333 ? 23  THR A CA  1 
ATOM   178  C C   . THR A 1  26  ? 11.06301  2.37140   33.04398  1.000 27.87784 ? 23  THR A C   1 
ATOM   179  O O   . THR A 1  26  ? 10.25926  1.81467   33.79466  1.000 25.71713 ? 23  THR A O   1 
ATOM   180  C CB  . THR A 1  26  ? 13.43617  1.64680   32.96559  1.000 25.93150 ? 23  THR A CB  1 
ATOM   181  O OG1 . THR A 1  26  ? 13.20653  0.40842   33.64971  1.000 27.42493 ? 23  THR A OG1 1 
ATOM   182  C CG2 . THR A 1  26  ? 14.88903  2.06351   33.14864  1.000 24.19302 ? 23  THR A CG2 1 
ATOM   183  N N   . HIS A 1  27  ? 10.77712  2.70822   31.78995  1.000 22.79590 ? 24  HIS A N   1 
ATOM   184  C CA  . HIS A 1  27  ? 9.62952   2.17752   31.07183  1.000 25.38471 ? 24  HIS A CA  1 
ATOM   185  C C   . HIS A 1  27  ? 10.13012  1.25619   29.96851  1.000 29.02276 ? 24  HIS A C   1 
ATOM   186  O O   . HIS A 1  27  ? 11.08129  1.58980   29.25425  1.000 27.74519 ? 24  HIS A O   1 
ATOM   187  C CB  . HIS A 1  27  ? 8.76957   3.29424   30.47190  1.000 25.12587 ? 24  HIS A CB  1 
ATOM   188  C CG  . HIS A 1  27  ? 7.78041   3.88096   31.43085  1.000 29.42751 ? 24  HIS A CG  1 
ATOM   189  N ND1 . HIS A 1  27  ? 6.60967   4.48069   31.01776  1.000 30.10898 ? 24  HIS A ND1 1 
ATOM   190  C CD2 . HIS A 1  27  ? 7.78866   3.96396   32.78252  1.000 23.33839 ? 24  HIS A CD2 1 
ATOM   191  C CE1 . HIS A 1  27  ? 5.93869   4.90582   32.07353  1.000 28.02038 ? 24  HIS A CE1 1 
ATOM   192  N NE2 . HIS A 1  27  ? 6.63232   4.60465   33.15667  1.000 27.23709 ? 24  HIS A NE2 1 
ATOM   193  N N   . GLU A 1  28  ? 9.49735   0.09390   29.83955  1.000 24.30188 ? 25  GLU A N   1 
ATOM   194  C CA  . GLU A 1  28  ? 9.85905   -0.88978  28.82988  1.000 23.07282 ? 25  GLU A CA  1 
ATOM   195  C C   . GLU A 1  28  ? 8.65716   -1.17520  27.94125  1.000 28.04405 ? 25  GLU A C   1 
ATOM   196  O O   . GLU A 1  28  ? 7.51552   -1.18759  28.41234  1.000 23.49321 ? 25  GLU A O   1 
ATOM   197  C CB  . GLU A 1  28  ? 10.35401  -2.19251  29.47259  1.000 22.19432 ? 25  GLU A CB  1 
ATOM   198  C CG  . GLU A 1  28  ? 11.62072  -2.04630  30.30440  1.000 22.99024 ? 25  GLU A CG  1 
ATOM   199  C CD  . GLU A 1  28  ? 12.05381  -3.35630  30.94027  1.000 26.83703 ? 25  GLU A CD  1 
ATOM   200  O OE1 . GLU A 1  28  ? 11.37138  -4.37905  30.72215  1.000 29.00152 ? 25  GLU A OE1 1 
ATOM   201  O OE2 . GLU A 1  28  ? 13.07696  -3.36583  31.65716  1.000 29.43326 ? 25  GLU A OE2 1 
ATOM   202  N N   . PHE A 1  29  ? 8.91572   -1.39549  26.65258  1.000 21.98419 ? 26  PHE A N   1 
ATOM   203  C CA  . PHE A 1  29  ? 7.87221   -1.79008  25.71282  1.000 27.71497 ? 26  PHE A CA  1 
ATOM   204  C C   . PHE A 1  29  ? 8.39616   -2.91745  24.83931  1.000 24.64741 ? 26  PHE A C   1 
ATOM   205  O O   . PHE A 1  29  ? 9.39889   -2.74637  24.13856  1.000 25.86831 ? 26  PHE A O   1 
ATOM   206  C CB  . PHE A 1  29  ? 7.40993   -0.61760  24.84469  1.000 25.77215 ? 26  PHE A CB  1 
ATOM   207  C CG  . PHE A 1  29  ? 6.24545   -0.95607  23.96049  1.000 28.54969 ? 26  PHE A CG  1 
ATOM   208  C CD1 . PHE A 1  29  ? 4.95780   -0.98422  24.47181  1.000 25.21336 ? 26  PHE A CD1 1 
ATOM   209  C CD2 . PHE A 1  29  ? 6.43841   -1.26820  22.62570  1.000 29.21689 ? 26  PHE A CD2 1 
ATOM   210  C CE1 . PHE A 1  29  ? 3.88222   -1.30556  23.66435  1.000 28.54322 ? 26  PHE A CE1 1 
ATOM   211  C CE2 . PHE A 1  29  ? 5.36657   -1.59027  21.81283  1.000 33.46507 ? 26  PHE A CE2 1 
ATOM   212  C CZ  . PHE A 1  29  ? 4.08697   -1.60846  22.33339  1.000 29.07316 ? 26  PHE A CZ  1 
ATOM   213  N N   . ASP A 1  30  ? 7.70614   -4.05847  24.87889  1.000 19.44167 ? 27  ASP A N   1 
ATOM   214  C CA  . ASP A 1  30  ? 8.09835   -5.25697  24.13793  1.000 22.08604 ? 27  ASP A CA  1 
ATOM   215  C C   . ASP A 1  30  ? 9.56130   -5.61276  24.39301  1.000 27.87109 ? 27  ASP A C   1 
ATOM   216  O O   . ASP A 1  30  ? 10.28174  -6.06229  23.49843  1.000 25.00239 ? 27  ASP A O   1 
ATOM   217  C CB  . ASP A 1  30  ? 7.81859   -5.09628  22.64207  1.000 29.07047 ? 27  ASP A CB  1 
ATOM   218  C CG  . ASP A 1  30  ? 6.38540   -5.44395  22.28029  1.000 34.05357 ? 27  ASP A CG  1 
ATOM   219  O OD1 . ASP A 1  30  ? 5.67101   -5.98740  23.14910  1.000 33.97158 ? 27  ASP A OD1 1 
ATOM   220  O OD2 . ASP A 1  30  ? 5.97209   -5.17705  21.13182  1.000 35.52371 ? 27  ASP A OD2 1 
ATOM   221  N N   . GLY A 1  31  ? 10.00489  -5.39793  25.63202  1.000 25.05198 ? 28  GLY A N   1 
ATOM   222  C CA  . GLY A 1  31  ? 11.32022  -5.81123  26.07003  1.000 22.41648 ? 28  GLY A CA  1 
ATOM   223  C C   . GLY A 1  31  ? 12.43237  -4.79887  25.89411  1.000 29.86514 ? 28  GLY A C   1 
ATOM   224  O O   . GLY A 1  31  ? 13.57469  -5.09542  26.26755  1.000 25.66897 ? 28  GLY A O   1 
ATOM   225  N N   . ASP A 1  32  ? 12.14821  -3.61787  25.35156  1.000 23.75248 ? 29  ASP A N   1 
ATOM   226  C CA  . ASP A 1  32  ? 13.17610  -2.62212  25.08539  1.000 27.26070 ? 29  ASP A CA  1 
ATOM   227  C C   . ASP A 1  32  ? 12.97265  -1.38405  25.95062  1.000 27.88892 ? 29  ASP A C   1 
ATOM   228  O O   . ASP A 1  32  ? 11.84456  -1.02014  26.29319  1.000 26.73256 ? 29  ASP A O   1 
ATOM   229  C CB  . ASP A 1  32  ? 13.18710  -2.22894  23.60618  1.000 24.67873 ? 29  ASP A CB  1 
ATOM   230  C CG  . ASP A 1  32  ? 13.72138  -3.33289  22.71904  1.000 27.72168 ? 29  ASP A CG  1 
ATOM   231  O OD1 . ASP A 1  32  ? 14.78359  -3.89931  23.05358  1.000 28.27360 ? 29  ASP A OD1 1 
ATOM   232  O OD2 . ASP A 1  32  ? 13.07759  -3.63974  21.69359  1.000 25.78184 ? 29  ASP A OD2 1 
ATOM   233  N N   . GLU A 1  33  ? 14.08544  -0.73568  26.28992  1.000 26.80871 ? 30  GLU A N   1 
ATOM   234  C CA  . GLU A 1  33  ? 14.07629  0.42388   27.17422  1.000 27.59808 ? 30  GLU A CA  1 
ATOM   235  C C   . GLU A 1  33  ? 13.58533  1.65568   26.42136  1.000 26.47480 ? 30  GLU A C   1 
ATOM   236  O O   . GLU A 1  33  ? 14.16090  2.03429   25.39575  1.000 29.59977 ? 30  GLU A O   1 
ATOM   237  C CB  . GLU A 1  33  ? 15.47649  0.66091   27.73807  1.000 26.53874 ? 30  GLU A CB  1 
ATOM   238  C CG  . GLU A 1  33  ? 15.57793  1.81897   28.71773  1.000 29.58495 ? 30  GLU A CG  1 
ATOM   239  C CD  . GLU A 1  33  ? 16.92952  1.87853   29.41324  1.000 38.83922 ? 30  GLU A CD  1 
ATOM   240  O OE1 . GLU A 1  33  ? 17.84273  1.12435   29.01320  1.000 28.59927 ? 30  GLU A OE1 1 
ATOM   241  O OE2 . GLU A 1  33  ? 17.07924  2.68091   30.35945  1.000 35.29078 ? 30  GLU A OE2 1 
ATOM   242  N N   . GLU A 1  34  ? 12.52574  2.28382   26.93187  1.000 28.08927 ? 31  GLU A N   1 
ATOM   243  C CA  . GLU A 1  34  ? 12.01903  3.51941   26.34537  1.000 33.33481 ? 31  GLU A CA  1 
ATOM   244  C C   . GLU A 1  34  ? 12.69933  4.75028   26.93145  1.000 30.83701 ? 31  GLU A C   1 
ATOM   245  O O   . GLU A 1  34  ? 13.05047  5.67577   26.19067  1.000 31.18165 ? 31  GLU A O   1 
ATOM   246  C CB  . GLU A 1  34  ? 10.50335  3.61915   26.54194  1.000 21.94502 ? 31  GLU A CB  1 
ATOM   247  C CG  . GLU A 1  34  ? 9.71632   2.48509   25.90578  1.000 22.59626 ? 31  GLU A CG  1 
ATOM   248  C CD  . GLU A 1  34  ? 8.21821   2.72100   25.94663  1.000 28.08594 ? 31  GLU A CD  1 
ATOM   249  O OE1 . GLU A 1  34  ? 7.65217   2.77016   27.05851  1.000 29.33791 ? 31  GLU A OE1 1 
ATOM   250  O OE2 . GLU A 1  34  ? 7.60614   2.85696   24.86655  1.000 30.46673 ? 31  GLU A OE2 1 
ATOM   251  N N   . PHE A 1  35  ? 12.88988  4.77448   28.24777  1.000 25.85258 ? 32  PHE A N   1 
ATOM   252  C CA  . PHE A 1  35  ? 13.59585  5.85368   28.92474  1.000 31.16439 ? 32  PHE A CA  1 
ATOM   253  C C   . PHE A 1  35  ? 13.93602  5.39369   30.33260  1.000 31.64284 ? 32  PHE A C   1 
ATOM   254  O O   . PHE A 1  35  ? 13.38491  4.40898   30.83314  1.000 28.38399 ? 32  PHE A O   1 
ATOM   255  C CB  . PHE A 1  35  ? 12.76977  7.14965   28.96694  1.000 29.91999 ? 32  PHE A CB  1 
ATOM   256  C CG  . PHE A 1  35  ? 11.55239  7.08066   29.85762  1.000 30.19932 ? 32  PHE A CG  1 
ATOM   257  C CD1 . PHE A 1  35  ? 11.64172  7.37070   31.21331  1.000 32.11752 ? 32  PHE A CD1 1 
ATOM   258  C CD2 . PHE A 1  35  ? 10.31350  6.75182   29.33212  1.000 30.89738 ? 32  PHE A CD2 1 
ATOM   259  C CE1 . PHE A 1  35  ? 10.52413  7.31268   32.02778  1.000 30.24957 ? 32  PHE A CE1 1 
ATOM   260  C CE2 . PHE A 1  35  ? 9.19043   6.69823   30.14134  1.000 31.86035 ? 32  PHE A CE2 1 
ATOM   261  C CZ  . PHE A 1  35  ? 9.29694   6.97689   31.49088  1.000 29.74221 ? 32  PHE A CZ  1 
ATOM   262  N N   . TYR A 1  36  ? 14.85416  6.12078   30.96233  1.000 30.37847 ? 33  TYR A N   1 
ATOM   263  C CA  . TYR A 1  36  ? 15.11862  5.97762   32.38351  1.000 30.12278 ? 33  TYR A CA  1 
ATOM   264  C C   . TYR A 1  36  ? 15.16949  7.35974   33.01523  1.000 32.32402 ? 33  TYR A C   1 
ATOM   265  O O   . TYR A 1  36  ? 15.37052  8.37033   32.33690  1.000 34.33490 ? 33  TYR A O   1 
ATOM   266  C CB  . TYR A 1  36  ? 16.42298  5.20571   32.66263  1.000 28.85448 ? 33  TYR A CB  1 
ATOM   267  C CG  . TYR A 1  36  ? 17.70841  5.94835   32.36115  1.000 30.98728 ? 33  TYR A CG  1 
ATOM   268  C CD1 . TYR A 1  36  ? 18.31373  6.75222   33.32082  1.000 36.62177 ? 33  TYR A CD1 1 
ATOM   269  C CD2 . TYR A 1  36  ? 18.33471  5.81753   31.12871  1.000 35.09894 ? 33  TYR A CD2 1 
ATOM   270  C CE1 . TYR A 1  36  ? 19.49295  7.42181   33.05313  1.000 39.07854 ? 33  TYR A CE1 1 
ATOM   271  C CE2 . TYR A 1  36  ? 19.51563  6.48154   30.85226  1.000 37.92938 ? 33  TYR A CE2 1 
ATOM   272  C CZ  . TYR A 1  36  ? 20.08976  7.28267   31.81804  1.000 43.02404 ? 33  TYR A CZ  1 
ATOM   273  O OH  . TYR A 1  36  ? 21.26439  7.94695   31.54830  1.000 42.30535 ? 33  TYR A OH  1 
ATOM   274  N N   . VAL A 1  37  ? 14.96936  7.39379   34.32777  1.000 33.93252 ? 34  VAL A N   1 
ATOM   275  C CA  . VAL A 1  37  ? 15.05143  8.62159   35.10737  1.000 34.93080 ? 34  VAL A CA  1 
ATOM   276  C C   . VAL A 1  37  ? 16.34279  8.57711   35.90860  1.000 35.08129 ? 34  VAL A C   1 
ATOM   277  O O   . VAL A 1  37  ? 16.55379  7.65877   36.71092  1.000 29.62772 ? 34  VAL A O   1 
ATOM   278  C CB  . VAL A 1  37  ? 13.83597  8.79734   36.02966  1.000 34.71665 ? 34  VAL A CB  1 
ATOM   279  C CG1 . VAL A 1  37  ? 14.07440  9.94432   36.99918  1.000 33.20834 ? 34  VAL A CG1 1 
ATOM   280  C CG2 . VAL A 1  37  ? 12.57930  9.04107   35.20966  1.000 30.60676 ? 34  VAL A CG2 1 
ATOM   281  N N   . ASP A 1  38  ? 17.21261  9.55526   35.67801  1.000 38.37113 ? 35  ASP A N   1 
ATOM   282  C CA  . ASP A 1  38  ? 18.40984  9.72819   36.49466  1.000 38.03357 ? 35  ASP A CA  1 
ATOM   283  C C   . ASP A 1  38  ? 17.97231  10.25510  37.85416  1.000 40.39346 ? 35  ASP A C   1 
ATOM   284  O O   . ASP A 1  38  ? 17.73424  11.45258  38.02258  1.000 42.80096 ? 35  ASP A O   1 
ATOM   285  C CB  . ASP A 1  38  ? 19.38769  10.67914  35.81333  1.000 40.17959 ? 35  ASP A CB  1 
ATOM   286  C CG  . ASP A 1  38  ? 20.76730  10.65491  36.44703  1.000 46.30648 ? 35  ASP A CG  1 
ATOM   287  O OD1 . ASP A 1  38  ? 20.87054  10.85141  37.67715  1.000 47.99979 ? 35  ASP A OD1 1 
ATOM   288  O OD2 . ASP A 1  38  ? 21.75262  10.44124  35.71016  1.000 48.41280 ? 35  ASP A OD2 1 
ATOM   289  N N   . LEU A 1  39  ? 17.85420  9.35448   38.83280  1.000 43.70325 ? 36  LEU A N   1 
ATOM   290  C CA  . LEU A 1  39  ? 17.32051  9.73228   40.13661  1.000 43.94241 ? 36  LEU A CA  1 
ATOM   291  C C   . LEU A 1  39  ? 18.23911  10.68198  40.89511  1.000 50.75696 ? 36  LEU A C   1 
ATOM   292  O O   . LEU A 1  39  ? 17.76492  11.40733  41.77587  1.000 50.96234 ? 36  LEU A O   1 
ATOM   293  C CB  . LEU A 1  39  ? 17.05152  8.48184   40.97496  1.000 40.92677 ? 36  LEU A CB  1 
ATOM   294  C CG  . LEU A 1  39  ? 16.10292  7.45743   40.34709  1.000 37.87609 ? 36  LEU A CG  1 
ATOM   295  C CD1 . LEU A 1  39  ? 16.19034  6.12538   41.07565  1.000 34.71639 ? 36  LEU A CD1 1 
ATOM   296  C CD2 . LEU A 1  39  ? 14.67111  7.97626   40.33484  1.000 37.86172 ? 36  LEU A CD2 1 
ATOM   297  N N   . GLU A 1  40  ? 19.53541  10.69622  40.57969  1.000 51.51571 ? 37  GLU A N   1 
ATOM   298  C CA  . GLU A 1  40  ? 20.43926  11.64869  41.21548  1.000 48.83267 ? 37  GLU A CA  1 
ATOM   299  C C   . GLU A 1  40  ? 20.34638  13.01891  40.55467  1.000 51.52058 ? 37  GLU A C   1 
ATOM   300  O O   . GLU A 1  40  ? 20.25968  14.04349  41.24021  1.000 52.25590 ? 37  GLU A O   1 
ATOM   301  C CB  . GLU A 1  40  ? 21.87732  11.12795  41.16823  1.000 56.47438 ? 37  GLU A CB  1 
ATOM   302  C CG  . GLU A 1  40  ? 22.00696  9.62777   41.37201  1.000 61.98828 ? 37  GLU A CG  1 
ATOM   303  C CD  . GLU A 1  40  ? 22.20564  8.87963   40.06757  1.000 74.58795 ? 37  GLU A CD  1 
ATOM   304  O OE1 . GLU A 1  40  ? 23.00260  9.34838   39.22659  1.000 77.57607 ? 37  GLU A OE1 1 
ATOM   305  O OE2 . GLU A 1  40  ? 21.56371  7.82361   39.88272  1.000 73.10125 ? 37  GLU A OE2 1 
ATOM   306  N N   . ARG A 1  41  ? 20.35964  13.05425  39.22198  1.000 48.74734 ? 38  ARG A N   1 
ATOM   307  C CA  . ARG A 1  41  ? 20.28824  14.31080  38.48908  1.000 49.02454 ? 38  ARG A CA  1 
ATOM   308  C C   . ARG A 1  41  ? 18.86519  14.82559  38.32231  1.000 51.70070 ? 38  ARG A C   1 
ATOM   309  O O   . ARG A 1  41  ? 18.69077  15.96481  37.87396  1.000 45.36046 ? 38  ARG A O   1 
ATOM   310  C CB  . ARG A 1  41  ? 20.93551  14.15411  37.11019  1.000 52.14200 ? 38  ARG A CB  1 
ATOM   311  C CG  . ARG A 1  41  ? 22.45437  14.15265  37.13188  1.000 56.32321 ? 38  ARG A CG  1 
ATOM   312  C CD  . ARG A 1  41  ? 23.02469  14.14510  35.72120  1.000 57.34082 ? 38  ARG A CD  1 
ATOM   313  N NE  . ARG A 1  41  ? 22.65424  15.33939  34.96998  1.000 70.18902 ? 38  ARG A NE  1 
ATOM   314  C CZ  . ARG A 1  41  ? 23.15068  16.55040  35.18606  1.000 75.25205 ? 38  ARG A CZ  1 
ATOM   315  N NH1 . ARG A 1  41  ? 24.05678  16.77023  36.12535  1.000 70.95549 ? 38  ARG A NH1 1 
ATOM   316  N NH2 . ARG A 1  41  ? 22.73004  17.56653  34.43787  1.000 78.03767 ? 38  ARG A NH2 1 
ATOM   317  N N   . LYS A 1  42  ? 17.85571  14.02258  38.66578  1.000 49.26011 ? 39  LYS A N   1 
ATOM   318  C CA  . LYS A 1  42  ? 16.45032  14.40543  38.52822  1.000 43.23534 ? 39  LYS A CA  1 
ATOM   319  C C   . LYS A 1  42  ? 16.13099  14.73048  37.06758  1.000 46.12076 ? 39  LYS A C   1 
ATOM   320  O O   . LYS A 1  42  ? 15.64208  15.80958  36.72768  1.000 50.11882 ? 39  LYS A O   1 
ATOM   321  C CB  . LYS A 1  42  ? 16.10746  15.58210  39.45152  1.000 48.82004 ? 39  LYS A CB  1 
ATOM   322  C CG  . LYS A 1  42  ? 15.87129  15.20438  40.90838  1.000 54.11079 ? 39  LYS A CG  1 
ATOM   323  C CD  . LYS A 1  42  ? 17.14975  14.78873  41.62511  1.000 55.52810 ? 39  LYS A CD  1 
ATOM   324  C CE  . LYS A 1  42  ? 17.03582  14.98125  43.13056  1.000 63.34617 ? 39  LYS A CE  1 
ATOM   325  N NZ  . LYS A 1  42  ? 17.51683  13.78689  43.88393  1.000 62.28340 ? 39  LYS A NZ  1 
ATOM   326  N N   . GLU A 1  43  ? 16.41895  13.76124  36.20185  1.000 43.73163 ? 40  GLU A N   1 
ATOM   327  C CA  . GLU A 1  43  ? 16.43333  13.98677  34.76388  1.000 44.65355 ? 40  GLU A CA  1 
ATOM   328  C C   . GLU A 1  43  ? 15.87305  12.77259  34.04149  1.000 40.73092 ? 40  GLU A C   1 
ATOM   329  O O   . GLU A 1  43  ? 16.23849  11.63675  34.35755  1.000 40.77483 ? 40  GLU A O   1 
ATOM   330  C CB  . GLU A 1  43  ? 17.86188  14.27171  34.28598  1.000 49.92786 ? 40  GLU A CB  1 
ATOM   331  C CG  . GLU A 1  43  ? 17.96777  14.99168  32.95831  1.000 55.53901 ? 40  GLU A CG  1 
ATOM   332  C CD  . GLU A 1  43  ? 19.41064  15.19092  32.53373  1.000 68.83353 ? 40  GLU A CD  1 
ATOM   333  O OE1 . GLU A 1  43  ? 20.18503  15.78343  33.31591  1.000 65.99195 ? 40  GLU A OE1 1 
ATOM   334  O OE2 . GLU A 1  43  ? 19.77200  14.75087  31.42222  1.000 68.82026 ? 40  GLU A OE2 1 
ATOM   335  N N   . THR A 1  44  ? 14.99320  13.01509  33.07323  1.000 41.72794 ? 41  THR A N   1 
ATOM   336  C CA  . THR A 1  44  ? 14.48460  11.96169  32.20392  1.000 38.60829 ? 41  THR A CA  1 
ATOM   337  C C   . THR A 1  44  ? 15.40748  11.83496  30.99807  1.000 37.76067 ? 41  THR A C   1 
ATOM   338  O O   . THR A 1  44  ? 15.61120  12.80709  30.26283  1.000 41.95953 ? 41  THR A O   1 
ATOM   339  C CB  . THR A 1  44  ? 13.05450  12.25953  31.75215  1.000 37.98515 ? 41  THR A CB  1 
ATOM   340  O OG1 . THR A 1  44  ? 12.18055  12.27235  32.88729  1.000 37.63512 ? 41  THR A OG1 1 
ATOM   341  C CG2 . THR A 1  44  ? 12.57687  11.20149  30.76857  1.000 36.62273 ? 41  THR A CG2 1 
ATOM   342  N N   . VAL A 1  45  ? 15.96844  10.64530  30.80097  1.000 36.59838 ? 42  VAL A N   1 
ATOM   343  C CA  . VAL A 1  45  ? 16.85867  10.36303  29.68030  1.000 37.36973 ? 42  VAL A CA  1 
ATOM   344  C C   . VAL A 1  45  ? 16.12936  9.42694   28.72839  1.000 34.44652 ? 42  VAL A C   1 
ATOM   345  O O   . VAL A 1  45  ? 15.81785  8.28424   29.08618  1.000 35.02645 ? 42  VAL A O   1 
ATOM   346  C CB  . VAL A 1  45  ? 18.18714  9.75063   30.14720  1.000 41.01457 ? 42  VAL A CB  1 
ATOM   347  C CG1 . VAL A 1  45  ? 19.07570  9.44943   28.95116  1.000 32.33604 ? 42  VAL A CG1 1 
ATOM   348  C CG2 . VAL A 1  45  ? 18.88864  10.68481  31.12205  1.000 37.38172 ? 42  VAL A CG2 1 
ATOM   349  N N   . TRP A 1  46  ? 15.86773  9.90476   27.51594  1.000 34.22410 ? 43  TRP A N   1 
ATOM   350  C CA  . TRP A 1  46  ? 15.07404  9.16206   26.54864  1.000 35.05891 ? 43  TRP A CA  1 
ATOM   351  C C   . TRP A 1  46  ? 15.94893  8.22639   25.72609  1.000 41.76420 ? 43  TRP A C   1 
ATOM   352  O O   . TRP A 1  46  ? 17.05368  8.58839   25.31050  1.000 37.37378 ? 43  TRP A O   1 
ATOM   353  C CB  . TRP A 1  46  ? 14.32123  10.12234  25.62836  1.000 34.31991 ? 43  TRP A CB  1 
ATOM   354  C CG  . TRP A 1  46  ? 13.12364  10.72109  26.28487  1.000 35.06331 ? 43  TRP A CG  1 
ATOM   355  C CD1 . TRP A 1  46  ? 13.04563  11.93682  26.89739  1.000 42.29486 ? 43  TRP A CD1 1 
ATOM   356  C CD2 . TRP A 1  46  ? 11.83029  10.12249  26.41329  1.000 38.07407 ? 43  TRP A CD2 1 
ATOM   357  N NE1 . TRP A 1  46  ? 11.78024  12.13619  27.39348  1.000 39.43296 ? 43  TRP A NE1 1 
ATOM   358  C CE2 . TRP A 1  46  ? 11.01470  11.03620  27.10897  1.000 40.22827 ? 43  TRP A CE2 1 
ATOM   359  C CE3 . TRP A 1  46  ? 11.28114  8.90410   26.00312  1.000 35.34119 ? 43  TRP A CE3 1 
ATOM   360  C CZ2 . TRP A 1  46  ? 9.67998   10.77002  27.40387  1.000 41.95943 ? 43  TRP A CZ2 1 
ATOM   361  C CZ3 . TRP A 1  46  ? 9.95669   8.64179   26.29653  1.000 37.49277 ? 43  TRP A CZ3 1 
ATOM   362  C CH2 . TRP A 1  46  ? 9.17108   9.56962   26.99091  1.000 39.45464 ? 43  TRP A CH2 1 
ATOM   363  N N   . LYS A 1  47  ? 15.44144  7.01484   25.49710  1.000 38.31603 ? 44  LYS A N   1 
ATOM   364  C CA  . LYS A 1  47  ? 16.13452  6.00818   24.70879  1.000 32.55096 ? 44  LYS A CA  1 
ATOM   365  C C   . LYS A 1  47  ? 15.36383  5.59781   23.46331  1.000 38.15659 ? 44  LYS A C   1 
ATOM   366  O O   . LYS A 1  47  ? 15.79805  4.67562   22.76268  1.000 39.63118 ? 44  LYS A O   1 
ATOM   367  C CB  . LYS A 1  47  ? 16.42011  4.76335   25.56155  1.000 38.99648 ? 44  LYS A CB  1 
ATOM   368  C CG  . LYS A 1  47  ? 17.15558  5.04456   26.86467  1.000 37.74695 ? 44  LYS A CG  1 
ATOM   369  C CD  . LYS A 1  47  ? 18.39724  5.88922   26.63546  1.000 39.36963 ? 44  LYS A CD  1 
ATOM   370  C CE  . LYS A 1  47  ? 19.65356  5.03469   26.63537  1.000 45.54959 ? 44  LYS A CE  1 
ATOM   371  N NZ  . LYS A 1  47  ? 19.74160  4.17641   27.84918  1.000 49.48623 ? 44  LYS A NZ  1 
ATOM   372  N N   . LEU A 1  48  ? 14.23951  6.24423   23.17233  1.000 38.53118 ? 45  LEU A N   1 
ATOM   373  C CA  . LEU A 1  48  ? 13.46035  5.89919   21.99227  1.000 37.88128 ? 45  LEU A CA  1 
ATOM   374  C C   . LEU A 1  48  ? 14.26867  6.19782   20.73239  1.000 38.47069 ? 45  LEU A C   1 
ATOM   375  O O   . LEU A 1  48  ? 14.83382  7.29349   20.61023  1.000 34.66634 ? 45  LEU A O   1 
ATOM   376  C CB  . LEU A 1  48  ? 12.14585  6.67941   21.97107  1.000 33.80247 ? 45  LEU A CB  1 
ATOM   377  C CG  . LEU A 1  48  ? 11.04944  6.24710   22.94767  1.000 32.44122 ? 45  LEU A CG  1 
ATOM   378  C CD1 . LEU A 1  48  ? 9.74565   6.97142   22.63977  1.000 29.28768 ? 45  LEU A CD1 1 
ATOM   379  C CD2 . LEU A 1  48  ? 10.85192  4.73996   22.91013  1.000 29.01788 ? 45  LEU A CD2 1 
ATOM   380  N N   . PRO A 1  49  ? 14.34881  5.25844   19.77355  1.000 37.53885 ? 46  PRO A N   1 
ATOM   381  C CA  . PRO A 1  49  ? 15.13421  5.45809   18.54809  1.000 38.04841 ? 46  PRO A CA  1 
ATOM   382  C C   . PRO A 1  49  ? 14.38075  6.23432   17.46850  1.000 41.52094 ? 46  PRO A C   1 
ATOM   383  O O   . PRO A 1  49  ? 14.29227  5.80528   16.31633  1.000 37.80385 ? 46  PRO A O   1 
ATOM   384  C CB  . PRO A 1  49  ? 15.43716  4.02377   18.10909  1.000 34.82253 ? 46  PRO A CB  1 
ATOM   385  C CG  . PRO A 1  49  ? 14.22951  3.25251   18.55321  1.000 34.89598 ? 46  PRO A CG  1 
ATOM   386  C CD  . PRO A 1  49  ? 13.67869  3.94561   19.78615  1.000 34.38073 ? 46  PRO A CD  1 
ATOM   387  N N   . LEU A 1  50  ? 13.83936  7.39026   17.84533  1.000 39.70416 ? 47  LEU A N   1 
ATOM   388  C CA  . LEU A 1  50  ? 13.00576  8.18009   16.95095  1.000 37.58633 ? 47  LEU A CA  1 
ATOM   389  C C   . LEU A 1  50  ? 12.88559  9.59215   17.50525  1.000 41.69859 ? 47  LEU A C   1 
ATOM   390  O O   . LEU A 1  50  ? 13.18570  9.84753   18.67464  1.000 38.74725 ? 47  LEU A O   1 
ATOM   391  C CB  . LEU A 1  50  ? 11.62379  7.53829   16.77331  1.000 44.64626 ? 47  LEU A CB  1 
ATOM   392  C CG  . LEU A 1  50  ? 10.69212  7.55684   17.98969  1.000 40.55411 ? 47  LEU A CG  1 
ATOM   393  C CD1 . LEU A 1  50  ? 9.61295   8.62167   17.85569  1.000 51.60543 ? 47  LEU A CD1 1 
ATOM   394  C CD2 . LEU A 1  50  ? 10.07335  6.18133   18.20785  1.000 37.53758 ? 47  LEU A CD2 1 
ATOM   395  N N   . PHE A 1  51  ? 12.45314  10.50917  16.64101  1.000 49.06171 ? 48  PHE A N   1 
ATOM   396  C CA  . PHE A 1  51  ? 12.20781  11.88601  17.04875  1.000 52.92125 ? 48  PHE A CA  1 
ATOM   397  C C   . PHE A 1  51  ? 10.80609  12.03177  17.62368  1.000 45.59417 ? 48  PHE A C   1 
ATOM   398  O O   . PHE A 1  51  ? 9.82187   11.59800  17.01893  1.000 47.45528 ? 48  PHE A O   1 
ATOM   399  C CB  . PHE A 1  51  ? 12.37468  12.84383  15.86891  1.000 53.27349 ? 48  PHE A CB  1 
ATOM   400  C CG  . PHE A 1  51  ? 12.01488  14.26691  16.19559  1.000 58.11828 ? 48  PHE A CG  1 
ATOM   401  C CD1 . PHE A 1  51  ? 12.88540  15.06483  16.91795  1.000 61.92307 ? 48  PHE A CD1 1 
ATOM   402  C CD2 . PHE A 1  51  ? 10.79651  14.79943  15.79944  1.000 59.07333 ? 48  PHE A CD2 1 
ATOM   403  C CE1 . PHE A 1  51  ? 12.55687  16.37003  17.22850  1.000 61.97954 ? 48  PHE A CE1 1 
ATOM   404  C CE2 . PHE A 1  51  ? 10.46089  16.10474  16.10863  1.000 61.51221 ? 48  PHE A CE2 1 
ATOM   405  C CZ  . PHE A 1  51  ? 11.34296  16.89097  16.82402  1.000 61.63324 ? 48  PHE A CZ  1 
ATOM   406  N N   . HIS A 1  52  ? 10.71674  12.67652  18.78284  1.000 51.31670 ? 49  HIS A N   1 
ATOM   407  C CA  . HIS A 1  52  ? 9.44354   12.80602  19.47473  1.000 43.45622 ? 49  HIS A CA  1 
ATOM   408  C C   . HIS A 1  52  ? 9.51161   13.98749  20.42943  1.000 40.19078 ? 49  HIS A C   1 
ATOM   409  O O   . HIS A 1  52  ? 10.58982  14.50306  20.73587  1.000 46.71350 ? 49  HIS A O   1 
ATOM   410  C CB  . HIS A 1  52  ? 9.09882   11.52241  20.23184  1.000 41.44469 ? 49  HIS A CB  1 
ATOM   411  C CG  . HIS A 1  52  ? 10.09062  11.17555  21.29613  1.000 42.49788 ? 49  HIS A CG  1 
ATOM   412  N ND1 . HIS A 1  52  ? 10.04057  11.71572  22.56297  1.000 42.25460 ? 49  HIS A ND1 1 
ATOM   413  C CD2 . HIS A 1  52  ? 11.17216  10.36119  21.27620  1.000 36.92571 ? 49  HIS A CD2 1 
ATOM   414  C CE1 . HIS A 1  52  ? 11.04215  11.24083  23.28135  1.000 40.72696 ? 49  HIS A CE1 1 
ATOM   415  N NE2 . HIS A 1  52  ? 11.74364  10.41646  22.52431  1.000 45.90218 ? 49  HIS A NE2 1 
ATOM   416  N N   . ARG A 1  53  ? 8.33716   14.40578  20.90100  1.000 50.47830 ? 50  ARG A N   1 
ATOM   417  C CA  . ARG A 1  53  ? 8.21879   15.48655  21.87102  1.000 53.21634 ? 50  ARG A CA  1 
ATOM   418  C C   . ARG A 1  53  ? 7.70574   14.99414  23.21986  1.000 53.24975 ? 50  ARG A C   1 
ATOM   419  O O   . ARG A 1  53  ? 7.16492   15.78450  23.99993  1.000 51.53360 ? 50  ARG A O   1 
ATOM   420  C CB  . ARG A 1  53  ? 7.30807   16.58859  21.32809  1.000 54.29041 ? 50  ARG A CB  1 
ATOM   421  N N   . LEU A 1  54  ? 7.86886   13.70579  23.50986  1.000 47.04364 ? 51  LEU A N   1 
ATOM   422  C CA  . LEU A 1  54  ? 7.32935   13.13640  24.73666  1.000 45.43147 ? 51  LEU A CA  1 
ATOM   423  C C   . LEU A 1  54  ? 8.03862   13.70697  25.95851  1.000 46.15316 ? 51  LEU A C   1 
ATOM   424  O O   . LEU A 1  54  ? 9.25429   13.92010  25.95206  1.000 48.86359 ? 51  LEU A O   1 
ATOM   425  C CB  . LEU A 1  54  ? 7.46276   11.61409  24.71651  1.000 42.88687 ? 51  LEU A CB  1 
ATOM   426  C CG  . LEU A 1  54  ? 6.54056   10.84412  23.76940  1.000 44.22820 ? 51  LEU A CG  1 
ATOM   427  C CD1 . LEU A 1  54  ? 6.56969   9.35897   24.09272  1.000 44.31883 ? 51  LEU A CD1 1 
ATOM   428  C CD2 . LEU A 1  54  ? 5.11823   11.38367  23.83876  1.000 42.37608 ? 51  LEU A CD2 1 
ATOM   429  N N   . ARG A 1  55  ? 7.26682   13.95479  27.01304  1.000 44.60633 ? 52  ARG A N   1 
ATOM   430  C CA  . ARG A 1  55  ? 7.78862   14.48262  28.26413  1.000 49.37180 ? 52  ARG A CA  1 
ATOM   431  C C   . ARG A 1  55  ? 7.36064   13.57839  29.40832  1.000 44.28360 ? 52  ARG A C   1 
ATOM   432  O O   . ARG A 1  55  ? 6.24119   13.05917  29.41383  1.000 44.04856 ? 52  ARG A O   1 
ATOM   433  C CB  . ARG A 1  55  ? 7.29510   15.91288  28.51779  1.000 46.35082 ? 52  ARG A CB  1 
ATOM   434  C CG  . ARG A 1  55  ? 7.71119   16.91202  27.45245  1.000 54.64538 ? 52  ARG A CG  1 
ATOM   435  C CD  . ARG A 1  55  ? 9.15923   17.33378  27.63225  1.000 60.79600 ? 52  ARG A CD  1 
ATOM   436  N NE  . ARG A 1  55  ? 9.27297   18.58408  28.37303  1.000 68.77948 ? 52  ARG A NE  1 
ATOM   437  C CZ  . ARG A 1  55  ? 9.64626   19.73937  27.84032  1.000 66.32651 ? 52  ARG A CZ  1 
ATOM   438  N NH1 . ARG A 1  55  ? 9.94924   19.84294  26.55638  1.000 58.46481 ? 52  ARG A NH1 1 
ATOM   439  N NH2 . ARG A 1  55  ? 9.71812   20.81767  28.61550  1.000 66.30010 ? 52  ARG A NH2 1 
ATOM   440  N N   . PHE A 1  56  ? 8.25458   13.39012  30.37573  1.000 40.03637 ? 53  PHE A N   1 
ATOM   441  C CA  . PHE A 1  56  ? 7.94768   12.60195  31.56320  1.000 39.65047 ? 53  PHE A CA  1 
ATOM   442  C C   . PHE A 1  56  ? 8.54730   13.29372  32.77506  1.000 40.21239 ? 53  PHE A C   1 
ATOM   443  O O   . PHE A 1  56  ? 9.77024   13.43448  32.86796  1.000 41.78878 ? 53  PHE A O   1 
ATOM   444  C CB  . PHE A 1  56  ? 8.47947   11.17050  31.44289  1.000 39.30115 ? 53  PHE A CB  1 
ATOM   445  C CG  . PHE A 1  56  ? 7.96926   10.24637  32.51256  1.000 37.27567 ? 53  PHE A CG  1 
ATOM   446  C CD1 . PHE A 1  56  ? 6.76183   9.58552   32.35758  1.000 33.56632 ? 53  PHE A CD1 1 
ATOM   447  C CD2 . PHE A 1  56  ? 8.69337   10.04471  33.67668  1.000 36.79381 ? 53  PHE A CD2 1 
ATOM   448  C CE1 . PHE A 1  56  ? 6.28820   8.73716   33.34078  1.000 34.84255 ? 53  PHE A CE1 1 
ATOM   449  C CE2 . PHE A 1  56  ? 8.22390   9.19865   34.66542  1.000 31.80848 ? 53  PHE A CE2 1 
ATOM   450  C CZ  . PHE A 1  56  ? 7.02070   8.54372   34.49685  1.000 33.97077 ? 53  PHE A CZ  1 
ATOM   451  N N   . ASP A 1  57  ? 7.68475   13.72262  33.69431  1.000 40.38667 ? 54  ASP A N   1 
ATOM   452  C CA  . ASP A 1  57  ? 8.08654   14.35575  34.94287  1.000 39.60631 ? 54  ASP A CA  1 
ATOM   453  C C   . ASP A 1  57  ? 8.96572   13.40455  35.74563  1.000 43.21081 ? 54  ASP A C   1 
ATOM   454  O O   . ASP A 1  57  ? 8.49126   12.35569  36.20001  1.000 42.78496 ? 54  ASP A O   1 
ATOM   455  C CB  . ASP A 1  57  ? 6.85119   14.76107  35.75207  1.000 41.27649 ? 54  ASP A CB  1 
ATOM   456  C CG  . ASP A 1  57  ? 7.16943   15.74395  36.86743  1.000 49.92058 ? 54  ASP A CG  1 
ATOM   457  O OD1 . ASP A 1  57  ? 8.34298   15.82913  37.28838  1.000 50.61917 ? 54  ASP A OD1 1 
ATOM   458  O OD2 . ASP A 1  57  ? 6.23513   16.43316  37.32837  1.000 56.90319 ? 54  ASP A OD2 1 
ATOM   459  N N   . PRO A 1  58  ? 10.24746  13.72889  35.94018  1.000 38.05825 ? 55  PRO A N   1 
ATOM   460  C CA  . PRO A 1  58  ? 11.10816  12.84591  36.74356  1.000 41.32123 ? 55  PRO A CA  1 
ATOM   461  C C   . PRO A 1  58  ? 10.72220  12.79611  38.21089  1.000 43.42151 ? 55  PRO A C   1 
ATOM   462  O O   . PRO A 1  58  ? 11.14118  11.86494  38.90993  1.000 41.22579 ? 55  PRO A O   1 
ATOM   463  C CB  . PRO A 1  58  ? 12.51011  13.44312  36.55615  1.000 38.59284 ? 55  PRO A CB  1 
ATOM   464  C CG  . PRO A 1  58  ? 12.28322  14.85100  36.13077  1.000 46.88124 ? 55  PRO A CG  1 
ATOM   465  C CD  . PRO A 1  58  ? 10.97314  14.89264  35.40360  1.000 37.97899 ? 55  PRO A CD  1 
ATOM   466  N N   . GLN A 1  59  ? 9.93949   13.76096  38.70131  1.000 42.78584 ? 56  GLN A N   1 
ATOM   467  C CA  . GLN A 1  59  ? 9.50705   13.73071  40.09321  1.000 42.97215 ? 56  GLN A CA  1 
ATOM   468  C C   . GLN A 1  59  ? 8.60319   12.53955  40.38738  1.000 44.73167 ? 56  GLN A C   1 
ATOM   469  O O   . GLN A 1  59  ? 8.53753   12.09808  41.54015  1.000 37.39676 ? 56  GLN A O   1 
ATOM   470  C CB  . GLN A 1  59  ? 8.79917   15.04095  40.45102  1.000 44.55361 ? 56  GLN A CB  1 
ATOM   471  C CG  . GLN A 1  59  ? 8.37638   15.16080  41.90973  1.000 37.58931 ? 56  GLN A CG  1 
ATOM   472  C CD  . GLN A 1  59  ? 9.54832   15.07932  42.87158  1.000 48.94350 ? 56  GLN A CD  1 
ATOM   473  O OE1 . GLN A 1  59  ? 9.54374   14.27838  43.80797  1.000 43.48248 ? 56  GLN A OE1 1 
ATOM   474  N NE2 . GLN A 1  59  ? 10.55798  15.91210  42.64711  1.000 50.12653 ? 56  GLN A NE2 1 
ATOM   475  N N   . PHE A 1  60  ? 7.91396   12.00313  39.37532  1.000 41.86154 ? 57  PHE A N   1 
ATOM   476  C CA  . PHE A 1  60  ? 7.13350   10.78889  39.58947  1.000 38.82240 ? 57  PHE A CA  1 
ATOM   477  C C   . PHE A 1  60  ? 8.02763   9.63584   40.02400  1.000 38.27347 ? 57  PHE A C   1 
ATOM   478  O O   . PHE A 1  60  ? 7.68574   8.88831   40.94824  1.000 40.04471 ? 57  PHE A O   1 
ATOM   479  C CB  . PHE A 1  60  ? 6.36408   10.41226  38.32137  1.000 36.00336 ? 57  PHE A CB  1 
ATOM   480  C CG  . PHE A 1  60  ? 5.54283   9.15708   38.46477  1.000 37.01980 ? 57  PHE A CG  1 
ATOM   481  C CD1 . PHE A 1  60  ? 6.11533   7.90676   38.27814  1.000 31.84491 ? 57  PHE A CD1 1 
ATOM   482  C CD2 . PHE A 1  60  ? 4.20033   9.22805   38.79608  1.000 35.51873 ? 57  PHE A CD2 1 
ATOM   483  C CE1 . PHE A 1  60  ? 5.36916   6.75709   38.42541  1.000 31.99470 ? 57  PHE A CE1 1 
ATOM   484  C CE2 . PHE A 1  60  ? 3.44505   8.07887   38.93575  1.000 37.09927 ? 57  PHE A CE2 1 
ATOM   485  C CZ  . PHE A 1  60  ? 4.03053   6.84196   38.74953  1.000 34.52518 ? 57  PHE A CZ  1 
ATOM   486  N N   . ALA A 1  61  ? 9.17279   9.46976   39.35849  1.000 35.76121 ? 58  ALA A N   1 
ATOM   487  C CA  . ALA A 1  61  ? 10.06572  8.36317   39.68234  1.000 33.57808 ? 58  ALA A CA  1 
ATOM   488  C C   . ALA A 1  61  ? 10.60345  8.48271   41.10195  1.000 38.94044 ? 58  ALA A C   1 
ATOM   489  O O   . ALA A 1  61  ? 10.62848  7.49731   41.84799  1.000 39.21304 ? 58  ALA A O   1 
ATOM   490  C CB  . ALA A 1  61  ? 11.21312  8.30638   38.67484  1.000 30.97757 ? 58  ALA A CB  1 
ATOM   491  N N   . LEU A 1  62  ? 11.03186  9.68440   41.49598  1.000 31.56335 ? 59  LEU A N   1 
ATOM   492  C CA  . LEU A 1  62  ? 11.56332  9.87449   42.84148  1.000 37.69078 ? 59  LEU A CA  1 
ATOM   493  C C   . LEU A 1  62  ? 10.51630  9.55527   43.89909  1.000 37.26310 ? 59  LEU A C   1 
ATOM   494  O O   . LEU A 1  62  ? 10.82452  8.93046   44.92111  1.000 35.77025 ? 59  LEU A O   1 
ATOM   495  C CB  . LEU A 1  62  ? 12.06214  11.30630  43.00788  1.000 38.45592 ? 59  LEU A CB  1 
ATOM   496  C CG  . LEU A 1  62  ? 13.41075  11.62788  42.37446  1.000 45.98395 ? 59  LEU A CG  1 
ATOM   497  C CD1 . LEU A 1  62  ? 13.37233  13.04601  41.86558  1.000 48.52309 ? 59  LEU A CD1 1 
ATOM   498  C CD2 . LEU A 1  62  ? 14.53949  11.43824  43.37438  1.000 47.44809 ? 59  LEU A CD2 1 
ATOM   499  N N   . THR A 1  63  ? 9.27157   9.97967   43.67167  1.000 39.05386 ? 60  THR A N   1 
ATOM   500  C CA  . THR A 1  63  ? 8.20760   9.69527   44.62800  1.000 38.06810 ? 60  THR A CA  1 
ATOM   501  C C   . THR A 1  63  ? 7.90371   8.20361   44.68506  1.000 36.77876 ? 60  THR A C   1 
ATOM   502  O O   . THR A 1  63  ? 7.70197   7.64629   45.77044  1.000 38.46155 ? 60  THR A O   1 
ATOM   503  C CB  . THR A 1  63  ? 6.95150   10.48757  44.26525  1.000 40.56915 ? 60  THR A CB  1 
ATOM   504  O OG1 . THR A 1  63  ? 7.23570   11.89065  44.33175  1.000 42.64198 ? 60  THR A OG1 1 
ATOM   505  C CG2 . THR A 1  63  ? 5.81652   10.16148  45.22519  1.000 32.00758 ? 60  THR A CG2 1 
ATOM   506  N N   . ASN A 1  64  ? 7.87955   7.53707   43.52873  1.000 33.29667 ? 61  ASN A N   1 
ATOM   507  C CA  . ASN A 1  64  ? 7.60072   6.10542   43.51600  1.000 29.45931 ? 61  ASN A CA  1 
ATOM   508  C C   . ASN A 1  64  ? 8.72014   5.31490   44.18344  1.000 33.56769 ? 61  ASN A C   1 
ATOM   509  O O   . ASN A 1  64  ? 8.45308   4.38571   44.95442  1.000 34.38518 ? 61  ASN A O   1 
ATOM   510  C CB  . ASN A 1  64  ? 7.37944   5.62340   42.08297  1.000 34.39036 ? 61  ASN A CB  1 
ATOM   511  C CG  . ASN A 1  64  ? 6.20583   4.67137   41.96742  1.000 33.88464 ? 61  ASN A CG  1 
ATOM   512  O OD1 . ASN A 1  64  ? 5.25976   4.73900   42.75330  1.000 31.98483 ? 61  ASN A OD1 1 
ATOM   513  N ND2 . ASN A 1  64  ? 6.26280   3.77367   40.98961  1.000 29.17658 ? 61  ASN A ND2 1 
ATOM   514  N N   . ILE A 1  65  ? 9.97830   5.67184   43.90946  1.000 29.82606 ? 62  ILE A N   1 
ATOM   515  C CA  . ILE A 1  65  ? 11.09946  4.95099   44.50987  1.000 31.60773 ? 62  ILE A CA  1 
ATOM   516  C C   . ILE A 1  65  ? 11.10619  5.13564   46.02329  1.000 28.57625 ? 62  ILE A C   1 
ATOM   517  O O   . ILE A 1  65  ? 11.45148  4.21433   46.77383  1.000 33.35241 ? 62  ILE A O   1 
ATOM   518  C CB  . ILE A 1  65  ? 12.42931  5.39686   43.87254  1.000 30.60217 ? 62  ILE A CB  1 
ATOM   519  C CG1 . ILE A 1  65  ? 12.45151  5.04338   42.38282  1.000 36.25215 ? 62  ILE A CG1 1 
ATOM   520  C CG2 . ILE A 1  65  ? 13.61135  4.75263   44.58101  1.000 29.80038 ? 62  ILE A CG2 1 
ATOM   521  C CD1 . ILE A 1  65  ? 12.55868  3.55883   42.10364  1.000 34.56102 ? 62  ILE A CD1 1 
ATOM   522  N N   . ALA A 1  66  ? 10.71598  6.32268   46.49750  1.000 30.66031 ? 63  ALA A N   1 
ATOM   523  C CA  . ALA A 1  66  ? 10.60211  6.53936   47.93722  1.000 30.50850 ? 63  ALA A CA  1 
ATOM   524  C C   . ALA A 1  66  ? 9.60283   5.57997   48.57102  1.000 29.04766 ? 63  ALA A C   1 
ATOM   525  O O   . ALA A 1  66  ? 9.79170   5.15563   49.71674  1.000 37.36561 ? 63  ALA A O   1 
ATOM   526  C CB  . ALA A 1  66  ? 10.20274  7.98660   48.22497  1.000 29.69066 ? 63  ALA A CB  1 
ATOM   527  N N   . VAL A 1  67  ? 8.53686   5.22861   47.84767  1.000 28.69663 ? 64  VAL A N   1 
ATOM   528  C CA  . VAL A 1  67  ? 7.60299   4.22423   48.34661  1.000 30.46333 ? 64  VAL A CA  1 
ATOM   529  C C   . VAL A 1  67  ? 8.27189   2.85632   48.39720  1.000 32.74376 ? 64  VAL A C   1 
ATOM   530  O O   . VAL A 1  67  ? 8.10664   2.10468   49.36609  1.000 35.70535 ? 64  VAL A O   1 
ATOM   531  C CB  . VAL A 1  67  ? 6.32890   4.19980   47.48235  1.000 34.12054 ? 64  VAL A CB  1 
ATOM   532  C CG1 . VAL A 1  67  ? 5.36416   3.13471   47.98540  1.000 32.00019 ? 64  VAL A CG1 1 
ATOM   533  C CG2 . VAL A 1  67  ? 5.66522   5.56807   47.47235  1.000 31.72223 ? 64  VAL A CG2 1 
ATOM   534  N N   . LEU A 1  68  ? 9.03635   2.51196   47.35639  1.000 31.64585 ? 65  LEU A N   1 
ATOM   535  C CA  . LEU A 1  68  ? 9.75308   1.23999   47.34564  1.000 31.83003 ? 65  LEU A CA  1 
ATOM   536  C C   . LEU A 1  68  ? 10.72819  1.14697   48.51292  1.000 31.44222 ? 65  LEU A C   1 
ATOM   537  O O   . LEU A 1  68  ? 10.84659  0.09433   49.15194  1.000 31.69871 ? 65  LEU A O   1 
ATOM   538  C CB  . LEU A 1  68  ? 10.49085  1.06483   46.01684  1.000 24.68987 ? 65  LEU A CB  1 
ATOM   539  C CG  . LEU A 1  68  ? 9.74973   0.36470   44.87231  1.000 26.59308 ? 65  LEU A CG  1 
ATOM   540  C CD1 . LEU A 1  68  ? 8.79101   1.31176   44.17080  1.000 24.33160 ? 65  LEU A CD1 1 
ATOM   541  C CD2 . LEU A 1  68  ? 10.73728  -0.23590  43.87791  1.000 22.52157 ? 65  LEU A CD2 1 
ATOM   542  N N   . LYS A 1  69  ? 11.43720  2.24029   48.80386  1.000 32.31226 ? 66  LYS A N   1 
ATOM   543  C CA  . LYS A 1  69  ? 12.34576  2.25449   49.94585  1.000 34.95826 ? 66  LYS A CA  1 
ATOM   544  C C   . LYS A 1  69  ? 11.58878  2.04008   51.24964  1.000 33.35209 ? 66  LYS A C   1 
ATOM   545  O O   . LYS A 1  69  ? 12.06127  1.32620   52.14283  1.000 35.73896 ? 66  LYS A O   1 
ATOM   546  C CB  . LYS A 1  69  ? 13.11756  3.57389   49.97876  1.000 37.76821 ? 66  LYS A CB  1 
ATOM   547  C CG  . LYS A 1  69  ? 13.87011  3.83737   51.27428  1.000 37.05035 ? 66  LYS A CG  1 
ATOM   548  C CD  . LYS A 1  69  ? 14.66831  5.12941   51.18573  1.000 32.66468 ? 66  LYS A CD  1 
ATOM   549  C CE  . LYS A 1  69  ? 15.35845  5.44953   52.50071  1.000 35.79127 ? 66  LYS A CE  1 
ATOM   550  N NZ  . LYS A 1  69  ? 16.23976  6.64233   52.37624  1.000 40.95298 ? 66  LYS A NZ  1 
ATOM   551  N N   . HIS A 1  70  ? 10.40601  2.64533   51.37145  1.000 31.85965 ? 67  HIS A N   1 
ATOM   552  C CA  . HIS A 1  70  ? 9.58337   2.44838   52.56045  1.000 39.55347 ? 67  HIS A CA  1 
ATOM   553  C C   . HIS A 1  70  ? 9.16848   0.98841   52.70392  1.000 40.68975 ? 67  HIS A C   1 
ATOM   554  O O   . HIS A 1  70  ? 9.25377   0.40967   53.79354  1.000 39.63961 ? 67  HIS A O   1 
ATOM   555  C CB  . HIS A 1  70  ? 8.35636   3.35965   52.49454  1.000 30.89249 ? 67  HIS A CB  1 
ATOM   556  C CG  . HIS A 1  70  ? 7.34363   3.09432   53.56435  1.000 41.53325 ? 67  HIS A CG  1 
ATOM   557  N ND1 . HIS A 1  70  ? 7.51035   3.51037   54.86768  1.000 49.41896 ? 67  HIS A ND1 1 
ATOM   558  C CD2 . HIS A 1  70  ? 6.14972   2.45687   53.52301  1.000 41.74609 ? 67  HIS A CD2 1 
ATOM   559  C CE1 . HIS A 1  70  ? 6.46296   3.14072   55.58311  1.000 47.11275 ? 67  HIS A CE1 1 
ATOM   560  N NE2 . HIS A 1  70  ? 5.62310   2.49889   54.79114  1.000 44.68597 ? 67  HIS A NE2 1 
ATOM   561  N N   . ASN A 1  71  ? 8.72841   0.37073   51.60449  1.000 32.49907 ? 68  ASN A N   1 
ATOM   562  C CA  . ASN A 1  71  ? 8.25945   -1.01023  51.66887  1.000 33.74260 ? 68  ASN A CA  1 
ATOM   563  C C   . ASN A 1  71  ? 9.40718   -1.97983  51.92548  1.000 31.30665 ? 68  ASN A C   1 
ATOM   564  O O   . ASN A 1  71  ? 9.25842   -2.93247  52.70005  1.000 34.28321 ? 68  ASN A O   1 
ATOM   565  C CB  . ASN A 1  71  ? 7.52954   -1.37787  50.37648  1.000 34.06078 ? 68  ASN A CB  1 
ATOM   566  C CG  . ASN A 1  71  ? 6.20563   -0.65348  50.22724  1.000 33.80913 ? 68  ASN A CG  1 
ATOM   567  O OD1 . ASN A 1  71  ? 5.80813   0.12338   51.09488  1.000 34.54976 ? 68  ASN A OD1 1 
ATOM   568  N ND2 . ASN A 1  71  ? 5.51641   -0.90343  49.12058  1.000 32.24517 ? 68  ASN A ND2 1 
ATOM   569  N N   . LEU A 1  72  ? 10.55658  -1.75850  51.28148  1.000 30.56623 ? 69  LEU A N   1 
ATOM   570  C CA  . LEU A 1  72  ? 11.67969  -2.67875  51.43561  1.000 34.18661 ? 69  LEU A CA  1 
ATOM   571  C C   . LEU A 1  72  ? 12.15158  -2.74438  52.88309  1.000 37.05272 ? 69  LEU A C   1 
ATOM   572  O O   . LEU A 1  72  ? 12.40655  -3.83349  53.41101  1.000 30.43024 ? 69  LEU A O   1 
ATOM   573  C CB  . LEU A 1  72  ? 12.83088  -2.26398  50.51831  1.000 34.39416 ? 69  LEU A CB  1 
ATOM   574  C CG  . LEU A 1  72  ? 14.16334  -2.98544  50.74190  1.000 28.71415 ? 69  LEU A CG  1 
ATOM   575  C CD1 . LEU A 1  72  ? 14.01072  -4.49176  50.56736  1.000 25.38986 ? 69  LEU A CD1 1 
ATOM   576  C CD2 . LEU A 1  72  ? 15.23948  -2.44207  49.81392  1.000 34.82744 ? 69  LEU A CD2 1 
ATOM   577  N N   . ASN A 1  73  ? 12.26859  -1.58931  53.54313  1.000 30.88810 ? 70  ASN A N   1 
ATOM   578  C CA  . ASN A 1  73  ? 12.77632  -1.57080  54.91112  1.000 37.83841 ? 70  ASN A CA  1 
ATOM   579  C C   . ASN A 1  73  ? 11.84019  -2.29431  55.87087  1.000 37.76452 ? 70  ASN A C   1 
ATOM   580  O O   . ASN A 1  73  ? 12.30002  -2.90340  56.84329  1.000 36.57106 ? 70  ASN A O   1 
ATOM   581  C CB  . ASN A 1  73  ? 13.00561  -0.12875  55.36301  1.000 38.10536 ? 70  ASN A CB  1 
ATOM   582  C CG  . ASN A 1  73  ? 14.32121  0.43450   54.85749  1.000 44.36169 ? 70  ASN A CG  1 
ATOM   583  O OD1 . ASN A 1  73  ? 15.27069  -0.30881  54.60733  1.000 37.79502 ? 70  ASN A OD1 1 
ATOM   584  N ND2 . ASN A 1  73  ? 14.38249  1.75256   54.70051  1.000 43.29195 ? 70  ASN A ND2 1 
ATOM   585  N N   . ILE A 1  74  ? 10.53140  -2.24918  55.61590  1.000 36.12457 ? 71  ILE A N   1 
ATOM   586  C CA  . ILE A 1  74  ? 9.59874   -3.00894  56.44175  1.000 32.45654 ? 71  ILE A CA  1 
ATOM   587  C C   . ILE A 1  74  ? 9.70528   -4.49658  56.13060  1.000 38.39467 ? 71  ILE A C   1 
ATOM   588  O O   . ILE A 1  74  ? 9.70027   -5.33806  57.03785  1.000 38.70985 ? 71  ILE A O   1 
ATOM   589  C CB  . ILE A 1  74  ? 8.16311   -2.48639  56.24638  1.000 38.11586 ? 71  ILE A CB  1 
ATOM   590  C CG1 . ILE A 1  74  ? 7.95374   -1.19295  57.03505  1.000 43.29626 ? 71  ILE A CG1 1 
ATOM   591  C CG2 . ILE A 1  74  ? 7.14017   -3.53352  56.66624  1.000 37.30691 ? 71  ILE A CG2 1 
ATOM   592  C CD1 . ILE A 1  74  ? 7.11282   -0.16987  56.31086  1.000 40.24722 ? 71  ILE A CD1 1 
ATOM   593  N N   . LEU A 1  75  ? 9.82503   -4.84398  54.84629  1.000 35.84530 ? 72  LEU A N   1 
ATOM   594  C CA  . LEU A 1  75  ? 9.85213   -6.24975  54.45608  1.000 35.01181 ? 72  LEU A CA  1 
ATOM   595  C C   . LEU A 1  75  ? 11.15053  -6.93168  54.86809  1.000 34.22523 ? 72  LEU A C   1 
ATOM   596  O O   . LEU A 1  75  ? 11.17099  -8.15384  55.05672  1.000 32.17680 ? 72  LEU A O   1 
ATOM   597  C CB  . LEU A 1  75  ? 9.63743   -6.37720  52.94929  1.000 29.91362 ? 72  LEU A CB  1 
ATOM   598  C CG  . LEU A 1  75  ? 8.20640   -6.10970  52.48244  1.000 31.77904 ? 72  LEU A CG  1 
ATOM   599  C CD1 . LEU A 1  75  ? 8.10594   -6.23564  50.97413  1.000 34.27750 ? 72  LEU A CD1 1 
ATOM   600  C CD2 . LEU A 1  75  ? 7.23531   -7.05643  53.16902  1.000 33.27665 ? 72  LEU A CD2 1 
ATOM   601  N N   . ILE A 1  76  ? 12.24099  -6.17222  54.99829  1.000 33.50658 ? 73  ILE A N   1 
ATOM   602  C CA  . ILE A 1  76  ? 13.47575  -6.74420  55.52803  1.000 34.90212 ? 73  ILE A CA  1 
ATOM   603  C C   . ILE A 1  76  ? 13.24335  -7.27540  56.93642  1.000 34.73603 ? 73  ILE A C   1 
ATOM   604  O O   . ILE A 1  76  ? 13.71714  -8.36086  57.29565  1.000 38.43859 ? 73  ILE A O   1 
ATOM   605  C CB  . ILE A 1  76  ? 14.60983  -5.70224  55.48906  1.000 35.00336 ? 73  ILE A CB  1 
ATOM   606  C CG1 . ILE A 1  76  ? 15.07621  -5.47173  54.04947  1.000 35.55618 ? 73  ILE A CG1 1 
ATOM   607  C CG2 . ILE A 1  76  ? 15.77976  -6.14322  56.35733  1.000 32.51883 ? 73  ILE A CG2 1 
ATOM   608  C CD1 . ILE A 1  76  ? 15.90487  -4.21693  53.87112  1.000 31.39523 ? 73  ILE A CD1 1 
ATOM   609  N N   . LYS A 1  77  ? 12.48902  -6.53011  57.74730  1.000 36.48235 ? 74  LYS A N   1 
ATOM   610  C CA  . LYS A 1  77  ? 12.14576  -6.99797  59.08621  1.000 43.22973 ? 74  LYS A CA  1 
ATOM   611  C C   . LYS A 1  77  ? 11.22458  -8.21081  59.02570  1.000 42.44644 ? 74  LYS A C   1 
ATOM   612  O O   . LYS A 1  77  ? 11.49035  -9.23643  59.66333  1.000 37.83630 ? 74  LYS A O   1 
ATOM   613  C CB  . LYS A 1  77  ? 11.48902  -5.87034  59.88506  1.000 45.18640 ? 74  LYS A CB  1 
ATOM   614  C CG  . LYS A 1  77  ? 12.16048  -4.51390  59.73735  1.000 50.71910 ? 74  LYS A CG  1 
ATOM   615  C CD  . LYS A 1  77  ? 12.07287  -3.71385  61.02858  1.000 58.90692 ? 74  LYS A CD  1 
ATOM   616  C CE  . LYS A 1  77  ? 12.70699  -2.34006  60.87616  1.000 53.82289 ? 74  LYS A CE  1 
ATOM   617  N NZ  . LYS A 1  77  ? 11.86614  -1.42813  60.05106  1.000 57.87807 ? 74  LYS A NZ  1 
ATOM   618  N N   . ARG A 1  78  ? 10.13758  -8.11311  58.25239  1.000 39.99437 ? 75  ARG A N   1 
ATOM   619  C CA  . ARG A 1  78  ? 9.12324   -9.16426  58.25080  1.000 34.80177 ? 75  ARG A CA  1 
ATOM   620  C C   . ARG A 1  78  ? 9.67274   -10.49097 57.74381  1.000 36.24560 ? 75  ARG A C   1 
ATOM   621  O O   . ARG A 1  78  ? 9.17319   -11.55441 58.12903  1.000 35.15359 ? 75  ARG A O   1 
ATOM   622  C CB  . ARG A 1  78  ? 7.92195   -8.73592  57.40648  1.000 36.32193 ? 75  ARG A CB  1 
ATOM   623  C CG  . ARG A 1  78  ? 7.30865   -7.40797  57.82110  1.000 44.06303 ? 75  ARG A CG  1 
ATOM   624  C CD  . ARG A 1  78  ? 6.41685   -7.56406  59.04399  1.000 57.00859 ? 75  ARG A CD  1 
ATOM   625  N NE  . ARG A 1  78  ? 6.62725   -6.49495  60.01345  1.000 63.96678 ? 75  ARG A NE  1 
ATOM   626  C CZ  . ARG A 1  78  ? 7.51888   -6.53703  60.99449  1.000 65.94153 ? 75  ARG A CZ  1 
ATOM   627  N NH1 . ARG A 1  78  ? 8.30683   -7.58567  61.16838  1.000 59.97937 ? 75  ARG A NH1 1 
ATOM   628  N NH2 . ARG A 1  78  ? 7.62210   -5.50115  61.82260  1.000 74.88002 ? 75  ARG A NH2 1 
ATOM   629  N N   . SER A 1  79  ? 10.69142  -10.45506 56.88794  1.000 31.74892 ? 76  SER A N   1 
ATOM   630  C CA  . SER A 1  79  ? 11.28651  -11.66291 56.33356  1.000 35.13266 ? 76  SER A CA  1 
ATOM   631  C C   . SER A 1  79  ? 12.41858  -12.21248 57.19238  1.000 37.05483 ? 76  SER A C   1 
ATOM   632  O O   . SER A 1  79  ? 13.09044  -13.16019 56.77154  1.000 41.03744 ? 76  SER A O   1 
ATOM   633  C CB  . SER A 1  79  ? 11.80141  -11.39508 54.91589  1.000 31.33347 ? 76  SER A CB  1 
ATOM   634  O OG  . SER A 1  79  ? 12.92398  -10.52959 54.93744  1.000 30.00343 ? 76  SER A OG  1 
ATOM   635  N N   . ASN A 1  80  ? 12.63778  -11.64439 58.38056  1.000 38.74417 ? 77  ASN A N   1 
ATOM   636  C CA  . ASN A 1  80  ? 13.75544  -12.01733 59.25048  1.000 40.14457 ? 77  ASN A CA  1 
ATOM   637  C C   . ASN A 1  80  ? 15.08745  -11.85849 58.51626  1.000 40.09035 ? 77  ASN A C   1 
ATOM   638  O O   . ASN A 1  80  ? 15.95119  -12.73870 58.54032  1.000 39.06965 ? 77  ASN A O   1 
ATOM   639  C CB  . ASN A 1  80  ? 13.58570  -13.43805 59.79972  1.000 49.40399 ? 77  ASN A CB  1 
ATOM   640  C CG  . ASN A 1  80  ? 14.56234  -13.75259 60.92159  1.000 60.89295 ? 77  ASN A CG  1 
ATOM   641  O OD1 . ASN A 1  80  ? 14.99957  -12.85948 61.64844  1.000 60.23068 ? 77  ASN A OD1 1 
ATOM   642  N ND2 . ASN A 1  80  ? 14.90956  -15.02719 61.06530  1.000 61.44777 ? 77  ASN A ND2 1 
ATOM   643  N N   . SER A 1  81  ? 15.23737  -10.71409 57.84558  1.000 41.15018 ? 78  SER A N   1 
ATOM   644  C CA  . SER A 1  81  ? 16.46602  -10.35842 57.13308  1.000 41.69633 ? 78  SER A CA  1 
ATOM   645  C C   . SER A 1  81  ? 16.86084  -11.42639 56.11532  1.000 37.13625 ? 78  SER A C   1 
ATOM   646  O O   . SER A 1  81  ? 18.02979  -11.80319 56.00621  1.000 41.09579 ? 78  SER A O   1 
ATOM   647  C CB  . SER A 1  81  ? 17.61278  -10.08943 58.10998  1.000 36.48246 ? 78  SER A CB  1 
ATOM   648  O OG  . SER A 1  81  ? 17.39554  -8.88587  58.82537  1.000 47.75482 ? 78  SER A OG  1 
ATOM   649  N N   . THR A 1  82  ? 15.87912  -11.92403 55.36674  1.000 28.18950 ? 79  THR A N   1 
ATOM   650  C CA  . THR A 1  82  ? 16.16126  -12.84200 54.26825  1.000 32.01013 ? 79  THR A CA  1 
ATOM   651  C C   . THR A 1  82  ? 16.79635  -12.05740 53.12748  1.000 36.02120 ? 79  THR A C   1 
ATOM   652  O O   . THR A 1  82  ? 16.14534  -11.20987 52.50765  1.000 34.46119 ? 79  THR A O   1 
ATOM   653  C CB  . THR A 1  82  ? 14.88682  -13.54243 53.80704  1.000 37.22601 ? 79  THR A CB  1 
ATOM   654  O OG1 . THR A 1  82  ? 14.43522  -14.43998 54.82876  1.000 38.39411 ? 79  THR A OG1 1 
ATOM   655  C CG2 . THR A 1  82  ? 15.14869  -14.33135 52.53059  1.000 28.09933 ? 79  THR A CG2 1 
ATOM   656  N N   . ALA A 1  83  ? 18.06685  -12.32976 52.85553  1.000 33.24478 ? 80  ALA A N   1 
ATOM   657  C CA  . ALA A 1  83  ? 18.82582  -11.57900 51.86933  1.000 36.10987 ? 80  ALA A CA  1 
ATOM   658  C C   . ALA A 1  83  ? 18.64954  -12.16767 50.47493  1.000 30.75799 ? 80  ALA A C   1 
ATOM   659  O O   . ALA A 1  83  ? 18.20552  -13.30518 50.30069  1.000 32.65946 ? 80  ALA A O   1 
ATOM   660  C CB  . ALA A 1  83  ? 20.30846  -11.55816 52.23586  1.000 27.97550 ? 80  ALA A CB  1 
ATOM   661  N N   . ALA A 1  84  ? 19.01513  -11.37041 49.47528  1.000 28.43857 ? 81  ALA A N   1 
ATOM   662  C CA  . ALA A 1  84  ? 18.97512  -11.83120 48.09681  1.000 30.24173 ? 81  ALA A CA  1 
ATOM   663  C C   . ALA A 1  84  ? 19.99507  -12.94134 47.87391  1.000 27.97480 ? 81  ALA A C   1 
ATOM   664  O O   . ALA A 1  84  ? 21.06614  -12.96793 48.48684  1.000 30.85990 ? 81  ALA A O   1 
ATOM   665  C CB  . ALA A 1  84  ? 19.24517  -10.67323 47.13606  1.000 26.51635 ? 81  ALA A CB  1 
ATOM   666  N N   . THR A 1  85  ? 19.64671  -13.86856 46.98859  1.000 26.68665 ? 82  THR A N   1 
ATOM   667  C CA  . THR A 1  85  ? 20.52233  -14.97022 46.61312  1.000 35.62284 ? 82  THR A CA  1 
ATOM   668  C C   . THR A 1  85  ? 21.28216  -14.59995 45.34605  1.000 31.41473 ? 82  THR A C   1 
ATOM   669  O O   . THR A 1  85  ? 20.67847  -14.15628 44.36399  1.000 31.85763 ? 82  THR A O   1 
ATOM   670  C CB  . THR A 1  85  ? 19.71932  -16.25428 46.39436  1.000 33.56624 ? 82  THR A CB  1 
ATOM   671  O OG1 . THR A 1  85  ? 19.07732  -16.63261 47.61856  1.000 46.10655 ? 82  THR A OG1 1 
ATOM   672  C CG2 . THR A 1  85  ? 20.62657  -17.38390 45.93273  1.000 35.39873 ? 82  THR A CG2 1 
ATOM   673  N N   . ASN A 1  86  ? 22.60197  -14.77637 45.37347  1.000 32.35679 ? 83  ASN A N   1 
ATOM   674  C CA  . ASN A 1  86  ? 23.44208  -14.44973 44.22716  1.000 30.73631 ? 83  ASN A CA  1 
ATOM   675  C C   . ASN A 1  86  ? 23.27879  -15.51375 43.14942  1.000 38.12269 ? 83  ASN A C   1 
ATOM   676  O O   . ASN A 1  86  ? 23.49912  -16.70295 43.40342  1.000 41.68595 ? 83  ASN A O   1 
ATOM   677  C CB  . ASN A 1  86  ? 24.90741  -14.33934 44.64379  1.000 32.29436 ? 83  ASN A CB  1 
ATOM   678  C CG  . ASN A 1  86  ? 25.14125  -13.26532 45.68495  1.000 30.02804 ? 83  ASN A CG  1 
ATOM   679  O OD1 . ASN A 1  86  ? 24.64563  -12.14611 45.56212  1.000 32.56678 ? 83  ASN A OD1 1 
ATOM   680  N ND2 . ASN A 1  86  ? 25.91306  -13.59754 46.71273  1.000 36.62375 ? 83  ASN A ND2 1 
ATOM   681  N N   . GLU A 1  87  ? 22.89950  -15.08763 41.95010  1.000 32.45945 ? 84  GLU A N   1 
ATOM   682  C CA  . GLU A 1  87  ? 22.78077  -15.97604 40.80584  1.000 33.44770 ? 84  GLU A CA  1 
ATOM   683  C C   . GLU A 1  87  ? 24.05566  -15.93453 39.97405  1.000 30.11215 ? 84  GLU A C   1 
ATOM   684  O O   . GLU A 1  87  ? 24.78881  -14.94259 39.97633  1.000 27.30648 ? 84  GLU A O   1 
ATOM   685  C CB  . GLU A 1  87  ? 21.58124  -15.59159 39.93692  1.000 34.20055 ? 84  GLU A CB  1 
ATOM   686  C CG  . GLU A 1  87  ? 20.24452  -15.78049 40.62573  1.000 36.51444 ? 84  GLU A CG  1 
ATOM   687  C CD  . GLU A 1  87  ? 19.84910  -17.23856 40.71884  1.000 44.70543 ? 84  GLU A CD  1 
ATOM   688  O OE1 . GLU A 1  87  ? 20.20660  -18.00882 39.80285  1.000 47.81667 ? 84  GLU A OE1 1 
ATOM   689  O OE2 . GLU A 1  87  ? 19.19068  -17.61647 41.71121  1.000 46.83295 ? 84  GLU A OE2 1 
ATOM   690  N N   . VAL A 1  88  ? 24.31604  -17.02838 39.26564  1.000 33.00830 ? 85  VAL A N   1 
ATOM   691  C CA  . VAL A 1  88  ? 25.44719  -17.09961 38.34485  1.000 31.07333 ? 85  VAL A CA  1 
ATOM   692  C C   . VAL A 1  88  ? 25.03195  -16.46094 37.02462  1.000 30.33922 ? 85  VAL A C   1 
ATOM   693  O O   . VAL A 1  88  ? 24.14745  -16.98780 36.33420  1.000 32.19288 ? 85  VAL A O   1 
ATOM   694  C CB  . VAL A 1  88  ? 25.91608  -18.54856 38.13860  1.000 31.86822 ? 85  VAL A CB  1 
ATOM   695  C CG1 . VAL A 1  88  ? 27.06340  -18.59776 37.13681  1.000 28.22603 ? 85  VAL A CG1 1 
ATOM   696  C CG2 . VAL A 1  88  ? 26.33351  -19.16541 39.46412  1.000 33.37693 ? 85  VAL A CG2 1 
ATOM   697  N N   . PRO A 1  89  ? 25.62557  -15.33515 36.63777  1.000 30.56016 ? 86  PRO A N   1 
ATOM   698  C CA  . PRO A 1  89  ? 25.25561  -14.71270 35.36320  1.000 32.65413 ? 86  PRO A CA  1 
ATOM   699  C C   . PRO A 1  89  ? 25.79279  -15.50015 34.17847  1.000 29.35663 ? 86  PRO A C   1 
ATOM   700  O O   . PRO A 1  89  ? 26.79409  -16.21365 34.27656  1.000 30.69078 ? 86  PRO A O   1 
ATOM   701  C CB  . PRO A 1  89  ? 25.90018  -13.32507 35.44723  1.000 32.73007 ? 86  PRO A CB  1 
ATOM   702  C CG  . PRO A 1  89  ? 27.06744  -13.51720 36.35859  1.000 29.23937 ? 86  PRO A CG  1 
ATOM   703  C CD  . PRO A 1  89  ? 26.65076  -14.56163 37.36019  1.000 27.93882 ? 86  PRO A CD  1 
ATOM   704  N N   . GLU A 1  90  ? 25.10259  -15.36389 33.04706  1.000 31.23794 ? 87  GLU A N   1 
ATOM   705  C CA  . GLU A 1  90  ? 25.48062  -16.00592 31.79456  1.000 30.50955 ? 87  GLU A CA  1 
ATOM   706  C C   . GLU A 1  90  ? 25.83429  -14.92863 30.77975  1.000 32.69667 ? 87  GLU A C   1 
ATOM   707  O O   . GLU A 1  90  ? 25.04348  -14.00839 30.54630  1.000 30.87057 ? 87  GLU A O   1 
ATOM   708  C CB  . GLU A 1  90  ? 24.35026  -16.89269 31.26354  1.000 39.12116 ? 87  GLU A CB  1 
ATOM   709  C CG  . GLU A 1  90  ? 24.11631  -18.15705 32.07882  1.000 48.26672 ? 87  GLU A CG  1 
ATOM   710  C CD  . GLU A 1  90  ? 22.64277  -18.44011 32.31149  1.000 57.38002 ? 87  GLU A CD  1 
ATOM   711  O OE1 . GLU A 1  90  ? 21.81082  -17.98935 31.49529  1.000 54.29598 ? 87  GLU A OE1 1 
ATOM   712  O OE2 . GLU A 1  90  ? 22.31600  -19.11415 33.31168  1.000 65.92551 ? 87  GLU A OE2 1 
ATOM   713  N N   . VAL A 1  91  ? 27.01354  -15.04844 30.17393  1.000 23.46883 ? 88  VAL A N   1 
ATOM   714  C CA  . VAL A 1  91  ? 27.59477  -13.99046 29.35639  1.000 24.93310 ? 88  VAL A CA  1 
ATOM   715  C C   . VAL A 1  91  ? 27.76726  -14.49586 27.93105  1.000 32.62977 ? 88  VAL A C   1 
ATOM   716  O O   . VAL A 1  91  ? 28.27381  -15.60315 27.71478  1.000 29.27234 ? 88  VAL A O   1 
ATOM   717  C CB  . VAL A 1  91  ? 28.94012  -13.51341 29.93213  1.000 26.77351 ? 88  VAL A CB  1 
ATOM   718  C CG1 . VAL A 1  91  ? 29.46609  -12.32398 29.14462  1.000 22.82037 ? 88  VAL A CG1 1 
ATOM   719  C CG2 . VAL A 1  91  ? 28.78357  -13.16181 31.40270  1.000 28.47914 ? 88  VAL A CG2 1 
ATOM   720  N N   . THR A 1  92  ? 27.35141  -13.67804 26.96459  1.000 28.10498 ? 89  THR A N   1 
ATOM   721  C CA  . THR A 1  92  ? 27.51618  -13.95943 25.54561  1.000 27.38440 ? 89  THR A CA  1 
ATOM   722  C C   . THR A 1  92  ? 28.05378  -12.71606 24.85314  1.000 24.46697 ? 89  THR A C   1 
ATOM   723  O O   . THR A 1  92  ? 27.58578  -11.60311 25.11129  1.000 23.80995 ? 89  THR A O   1 
ATOM   724  C CB  . THR A 1  92  ? 26.18814  -14.38081 24.89006  1.000 26.46362 ? 89  THR A CB  1 
ATOM   725  O OG1 . THR A 1  92  ? 25.56929  -15.41132 25.66796  1.000 30.84654 ? 89  THR A OG1 1 
ATOM   726  C CG2 . THR A 1  92  ? 26.42576  -14.89569 23.47519  1.000 31.12040 ? 89  THR A CG2 1 
ATOM   727  N N   . VAL A 1  93  ? 29.03574  -12.90654 23.97478  1.000 23.23194 ? 90  VAL A N   1 
ATOM   728  C CA  . VAL A 1  93  ? 29.61901  -11.82340 23.19194  1.000 24.27069 ? 90  VAL A CA  1 
ATOM   729  C C   . VAL A 1  93  ? 29.39472  -12.12267 21.71764  1.000 21.81351 ? 90  VAL A C   1 
ATOM   730  O O   . VAL A 1  93  ? 29.68385  -13.23150 21.25304  1.000 25.09076 ? 90  VAL A O   1 
ATOM   731  C CB  . VAL A 1  93  ? 31.11808  -11.64136 23.49054  1.000 29.42987 ? 90  VAL A CB  1 
ATOM   732  C CG1 . VAL A 1  93  ? 31.69621  -10.52875 22.63119  1.000 26.33826 ? 90  VAL A CG1 1 
ATOM   733  C CG2 . VAL A 1  93  ? 31.32277  -11.33124 24.95364  1.000 30.09714 ? 90  VAL A CG2 1 
ATOM   734  N N   . PHE A 1  94  ? 28.88299  -11.13559 20.98689  1.000 22.41418 ? 91  PHE A N   1 
ATOM   735  C CA  . PHE A 1  94  ? 28.59752  -11.30569 19.56977  1.000 26.75429 ? 91  PHE A CA  1 
ATOM   736  C C   . PHE A 1  94  ? 28.57312  -9.93735  18.90654  1.000 25.59433 ? 91  PHE A C   1 
ATOM   737  O O   . PHE A 1  94  ? 28.43498  -8.90679  19.57059  1.000 27.90016 ? 91  PHE A O   1 
ATOM   738  C CB  . PHE A 1  94  ? 27.27213  -12.04694 19.34357  1.000 22.66233 ? 91  PHE A CB  1 
ATOM   739  C CG  . PHE A 1  94  ? 26.10695  -11.47325 20.10914  1.000 24.83761 ? 91  PHE A CG  1 
ATOM   740  C CD1 . PHE A 1  94  ? 25.87501  -11.83677 21.42765  1.000 28.74575 ? 91  PHE A CD1 1 
ATOM   741  C CD2 . PHE A 1  94  ? 25.23425  -10.58270 19.50330  1.000 24.65075 ? 91  PHE A CD2 1 
ATOM   742  C CE1 . PHE A 1  94  ? 24.79989  -11.31550 22.12964  1.000 28.64923 ? 91  PHE A CE1 1 
ATOM   743  C CE2 . PHE A 1  94  ? 24.15804  -10.05858 20.19899  1.000 27.87728 ? 91  PHE A CE2 1 
ATOM   744  C CZ  . PHE A 1  94  ? 23.94043  -10.42613 21.51409  1.000 21.89508 ? 91  PHE A CZ  1 
ATOM   745  N N   . SER A 1  95  ? 28.71270  -9.94272  17.58491  1.000 25.70985 ? 92  SER A N   1 
ATOM   746  C CA  . SER A 1  95  ? 28.71574  -8.71334  16.80853  1.000 25.87867 ? 92  SER A CA  1 
ATOM   747  C C   . SER A 1  95  ? 27.29724  -8.32695  16.40973  1.000 26.65291 ? 92  SER A C   1 
ATOM   748  O O   . SER A 1  95  ? 26.41624  -9.17845  16.25981  1.000 24.57987 ? 92  SER A O   1 
ATOM   749  C CB  . SER A 1  95  ? 29.58655  -8.86190  15.55917  1.000 21.48392 ? 92  SER A CB  1 
ATOM   750  O OG  . SER A 1  95  ? 28.87289  -9.48875  14.50781  1.000 24.50361 ? 92  SER A OG  1 
ATOM   751  N N   . LYS A 1  96  ? 27.08616  -7.01979  16.23988  1.000 24.29497 ? 93  LYS A N   1 
ATOM   752  C CA  . LYS A 1  96  ? 25.77479  -6.52655  15.83436  1.000 26.50516 ? 93  LYS A CA  1 
ATOM   753  C C   . LYS A 1  96  ? 25.48069  -6.86730  14.37812  1.000 27.84050 ? 93  LYS A C   1 
ATOM   754  O O   . LYS A 1  96  ? 24.35697  -7.25831  14.04196  1.000 26.61608 ? 93  LYS A O   1 
ATOM   755  C CB  . LYS A 1  96  ? 25.69353  -5.01607  16.06132  1.000 29.12529 ? 93  LYS A CB  1 
ATOM   756  C CG  . LYS A 1  96  ? 24.41227  -4.36414  15.55345  1.000 26.75254 ? 93  LYS A CG  1 
ATOM   757  C CD  . LYS A 1  96  ? 24.39526  -2.87339  15.86808  1.000 28.64767 ? 93  LYS A CD  1 
ATOM   758  C CE  . LYS A 1  96  ? 23.30481  -2.14292  15.09564  1.000 27.58069 ? 93  LYS A CE  1 
ATOM   759  N NZ  . LYS A 1  96  ? 21.93594  -2.50159  15.56558  1.000 29.20066 ? 93  LYS A NZ  1 
ATOM   760  N N   . SER A 1  97  ? 26.47254  -6.73594  13.51036  1.000 30.26609 ? 94  SER A N   1 
ATOM   761  C CA  . SER A 1  97  ? 26.32619  -6.91392  12.06968  1.000 29.96882 ? 94  SER A CA  1 
ATOM   762  C C   . SER A 1  97  ? 27.36761  -7.89271  11.56546  1.000 27.12221 ? 94  SER A C   1 
ATOM   763  O O   . SER A 1  97  ? 28.31721  -8.23297  12.28000  1.000 26.90065 ? 94  SER A O   1 
ATOM   764  C CB  . SER A 1  97  ? 26.47259  -5.56160  11.35142  1.000 30.91303 ? 94  SER A CB  1 
ATOM   765  O OG  . SER A 1  97  ? 25.43974  -4.66851  11.73159  1.000 43.39747 ? 94  SER A OG  1 
ATOM   766  N N   . PRO A 1  98  ? 27.20825  -8.39369  10.33700  1.000 24.96767 ? 95  PRO A N   1 
ATOM   767  C CA  . PRO A 1  98  ? 28.28765  -9.16707  9.71316   1.000 27.71229 ? 95  PRO A CA  1 
ATOM   768  C C   . PRO A 1  98  ? 29.59270  -8.38373  9.72519   1.000 23.51679 ? 95  PRO A C   1 
ATOM   769  O O   . PRO A 1  98  ? 29.61012  -7.16476  9.54234   1.000 22.95543 ? 95  PRO A O   1 
ATOM   770  C CB  . PRO A 1  98  ? 27.77494  -9.40101  8.28960   1.000 27.73647 ? 95  PRO A CB  1 
ATOM   771  C CG  . PRO A 1  98  ? 26.29423  -9.41994  8.44141   1.000 27.90436 ? 95  PRO A CG  1 
ATOM   772  C CD  . PRO A 1  98  ? 25.97376  -8.42703  9.52915   1.000 29.39095 ? 95  PRO A CD  1 
ATOM   773  N N   . VAL A 1  99  ? 30.69191  -9.09595  9.94832   1.000 22.23575 ? 96  VAL A N   1 
ATOM   774  C CA  . VAL A 1  99  ? 31.97450  -8.48260  10.27233  1.000 30.50427 ? 96  VAL A CA  1 
ATOM   775  C C   . VAL A 1  99  ? 32.81348  -8.37035  9.00768   1.000 27.13237 ? 96  VAL A C   1 
ATOM   776  O O   . VAL A 1  99  ? 33.20281  -9.38484  8.41662   1.000 30.22265 ? 96  VAL A O   1 
ATOM   777  C CB  . VAL A 1  99  ? 32.71662  -9.28316  11.35280  1.000 26.28459 ? 96  VAL A CB  1 
ATOM   778  C CG1 . VAL A 1  99  ? 34.10945  -8.70680  11.57487  1.000 25.02012 ? 96  VAL A CG1 1 
ATOM   779  C CG2 . VAL A 1  99  ? 31.91370  -9.29058  12.64563  1.000 22.15957 ? 96  VAL A CG2 1 
ATOM   780  N N   . THR A 1  100 ? 33.10485  -7.13710  8.60443   1.000 27.10883 ? 97  THR A N   1 
ATOM   781  C CA  . THR A 1  100 ? 34.02823  -6.85138  7.51500   1.000 32.97710 ? 97  THR A CA  1 
ATOM   782  C C   . THR A 1  100 ? 35.24254  -6.12241  8.07346   1.000 32.43255 ? 97  THR A C   1 
ATOM   783  O O   . THR A 1  100 ? 35.09768  -5.14902  8.82126   1.000 26.21996 ? 97  THR A O   1 
ATOM   784  C CB  . THR A 1  100 ? 33.36121  -6.00754  6.42614   1.000 28.46623 ? 97  THR A CB  1 
ATOM   785  O OG1 . THR A 1  100 ? 32.25237  -6.72732  5.87419   1.000 34.53408 ? 97  THR A OG1 1 
ATOM   786  C CG2 . THR A 1  100 ? 34.35391  -5.68467  5.31589   1.000 27.37329 ? 97  THR A CG2 1 
ATOM   787  N N   . LEU A 1  101 ? 36.43165  -6.59832  7.71286   1.000 29.78626 ? 98  LEU A N   1 
ATOM   788  C CA  . LEU A 1  101 ? 37.66438  -5.97706  8.17779   1.000 34.93096 ? 98  LEU A CA  1 
ATOM   789  C C   . LEU A 1  101 ? 37.72278  -4.51999  7.73445   1.000 33.24871 ? 98  LEU A C   1 
ATOM   790  O O   . LEU A 1  101 ? 37.52104  -4.20728  6.55767   1.000 31.29965 ? 98  LEU A O   1 
ATOM   791  C CB  . LEU A 1  101 ? 38.87589  -6.74354  7.64170   1.000 37.36612 ? 98  LEU A CB  1 
ATOM   792  C CG  . LEU A 1  101 ? 39.36085  -8.00459  8.37008   1.000 40.13114 ? 98  LEU A CG  1 
ATOM   793  C CD1 . LEU A 1  101 ? 39.99235  -7.64184  9.69827   1.000 49.69229 ? 98  LEU A CD1 1 
ATOM   794  C CD2 . LEU A 1  101 ? 38.25470  -9.03485  8.56881   1.000 52.07167 ? 98  LEU A CD2 1 
ATOM   795  N N   . GLY A 1  102 ? 37.98501  -3.62662  8.68614   1.000 31.07595 ? 99  GLY A N   1 
ATOM   796  C CA  . GLY A 1  102 ? 38.09605  -2.21273  8.39121   1.000 30.01370 ? 99  GLY A CA  1 
ATOM   797  C C   . GLY A 1  102 ? 36.78687  -1.47153  8.25077   1.000 36.91352 ? 99  GLY A C   1 
ATOM   798  O O   . GLY A 1  102 ? 36.79555  -0.31016  7.82677   1.000 37.68468 ? 99  GLY A O   1 
ATOM   799  N N   . GLN A 1  103 ? 35.66388  -2.09646  8.59579   1.000 38.23103 ? 100 GLN A N   1 
ATOM   800  C CA  . GLN A 1  103 ? 34.34704  -1.48532  8.46289   1.000 32.62318 ? 100 GLN A CA  1 
ATOM   801  C C   . GLN A 1  103 ? 33.70991  -1.35500  9.83900   1.000 32.12766 ? 100 GLN A C   1 
ATOM   802  O O   . GLN A 1  103 ? 33.55218  -2.37153  10.53615  1.000 31.83504 ? 100 GLN A O   1 
ATOM   803  C CB  . GLN A 1  103 ? 33.45868  -2.31718  7.53649   1.000 29.95366 ? 100 GLN A CB  1 
ATOM   804  C CG  . GLN A 1  103 ? 31.99066  -1.93565  7.57114   1.000 43.44138 ? 100 GLN A CG  1 
ATOM   805  C CD  . GLN A 1  103 ? 31.16451  -2.73406  6.58268   1.000 44.55867 ? 100 GLN A CD  1 
ATOM   806  O OE1 . GLN A 1  103 ? 31.50626  -2.82671  5.40368   1.000 45.29993 ? 100 GLN A OE1 1 
ATOM   807  N NE2 . GLN A 1  103 ? 30.07334  -3.32084  7.06042   1.000 41.25132 ? 100 GLN A NE2 1 
ATOM   808  N N   . PRO A 1  104 ? 33.31762  -0.15164  10.26074  1.000 32.19351 ? 101 PRO A N   1 
ATOM   809  C CA  . PRO A 1  104 ? 32.82247  0.04047   11.63098  1.000 35.45375 ? 101 PRO A CA  1 
ATOM   810  C C   . PRO A 1  104 ? 31.70429  -0.92805  11.99617  1.000 34.00689 ? 101 PRO A C   1 
ATOM   811  O O   . PRO A 1  104 ? 30.81439  -1.21686  11.19385  1.000 31.04824 ? 101 PRO A O   1 
ATOM   812  C CB  . PRO A 1  104 ? 32.32752  1.49024   11.62156  1.000 35.89434 ? 101 PRO A CB  1 
ATOM   813  C CG  . PRO A 1  104 ? 33.15675  2.15536   10.57624  1.000 37.96290 ? 101 PRO A CG  1 
ATOM   814  C CD  . PRO A 1  104 ? 33.38787  1.11552   9.51291   1.000 39.14045 ? 101 PRO A CD  1 
ATOM   815  N N   . ASN A 1  105 ? 31.76567  -1.43146  13.22758  1.000 30.55673 ? 102 ASN A N   1 
ATOM   816  C CA  . ASN A 1  105 ? 30.81745  -2.41378  13.73208  1.000 25.98412 ? 102 ASN A CA  1 
ATOM   817  C C   . ASN A 1  105 ? 30.62887  -2.16938  15.22500  1.000 28.59595 ? 102 ASN A C   1 
ATOM   818  O O   . ASN A 1  105 ? 31.16135  -1.20880  15.78834  1.000 25.78679 ? 102 ASN A O   1 
ATOM   819  C CB  . ASN A 1  105 ? 31.30390  -3.83982  13.44559  1.000 21.99687 ? 102 ASN A CB  1 
ATOM   820  C CG  . ASN A 1  105 ? 30.16508  -4.83513  13.32150  1.000 27.36129 ? 102 ASN A CG  1 
ATOM   821  O OD1 . ASN A 1  105 ? 29.21460  -4.81193  14.10593  1.000 23.74251 ? 102 ASN A OD1 1 
ATOM   822  N ND2 . ASN A 1  105 ? 30.26123  -5.72428  12.33815  1.000 26.33270 ? 102 ASN A ND2 1 
ATOM   823  N N   . THR A 1  106 ? 29.86299  -3.04956  15.86844  1.000 26.58630 ? 103 THR A N   1 
ATOM   824  C CA  . THR A 1  106 ? 29.59715  -2.94646  17.29777  1.000 22.48992 ? 103 THR A CA  1 
ATOM   825  C C   . THR A 1  106 ? 29.67029  -4.32816  17.92658  1.000 27.01396 ? 103 THR A C   1 
ATOM   826  O O   . THR A 1  106 ? 29.01002  -5.26031  17.45833  1.000 23.74013 ? 103 THR A O   1 
ATOM   827  C CB  . THR A 1  106 ? 28.21920  -2.32673  17.57350  1.000 23.24895 ? 103 THR A CB  1 
ATOM   828  O OG1 . THR A 1  106 ? 28.15367  -1.01433  17.00374  1.000 25.14757 ? 103 THR A OG1 1 
ATOM   829  C CG2 . THR A 1  106 ? 27.96601  -2.23301  19.07332  1.000 24.78592 ? 103 THR A CG2 1 
ATOM   830  N N   . LEU A 1  107 ? 30.47207  -4.45692  18.98078  1.000 23.74010 ? 104 LEU A N   1 
ATOM   831  C CA  . LEU A 1  107 ? 30.48310  -5.66311  19.79438  1.000 22.59478 ? 104 LEU A CA  1 
ATOM   832  C C   . LEU A 1  107 ? 29.41959  -5.55181  20.87836  1.000 20.57429 ? 104 LEU A C   1 
ATOM   833  O O   . LEU A 1  107 ? 29.23134  -4.48817  21.47476  1.000 23.70536 ? 104 LEU A O   1 
ATOM   834  C CB  . LEU A 1  107 ? 31.85781  -5.88920  20.42707  1.000 23.73901 ? 104 LEU A CB  1 
ATOM   835  C CG  . LEU A 1  107 ? 32.90283  -6.62155  19.58069  1.000 36.11319 ? 104 LEU A CG  1 
ATOM   836  C CD1 . LEU A 1  107 ? 34.02112  -7.17004  20.46198  1.000 27.61362 ? 104 LEU A CD1 1 
ATOM   837  C CD2 . LEU A 1  107 ? 32.26489  -7.73410  18.75590  1.000 27.43992 ? 104 LEU A CD2 1 
ATOM   838  N N   . ILE A 1  108 ? 28.72244  -6.65544  21.12672  1.000 22.32860 ? 105 ILE A N   1 
ATOM   839  C CA  . ILE A 1  108 ? 27.61797  -6.69821  22.07671  1.000 20.52649 ? 105 ILE A CA  1 
ATOM   840  C C   . ILE A 1  108 ? 27.94941  -7.72329  23.15008  1.000 21.59508 ? 105 ILE A C   1 
ATOM   841  O O   . ILE A 1  108 ? 28.26039  -8.87807  22.83632  1.000 25.68987 ? 105 ILE A O   1 
ATOM   842  C CB  . ILE A 1  108 ? 26.28750  -7.04318  21.38178  1.000 23.44788 ? 105 ILE A CB  1 
ATOM   843  C CG1 . ILE A 1  108 ? 25.93302  -5.98068  20.33965  1.000 26.09306 ? 105 ILE A CG1 1 
ATOM   844  C CG2 . ILE A 1  108 ? 25.17014  -7.18256  22.39878  1.000 25.33388 ? 105 ILE A CG2 1 
ATOM   845  C CD1 . ILE A 1  108 ? 24.61137  -6.23444  19.64035  1.000 27.11967 ? 105 ILE A CD1 1 
ATOM   846  N N   . CYS A 1  109 ? 27.89212  -7.30107  24.41029  1.000 17.82829 ? 106 CYS A N   1 
ATOM   847  C CA  . CYS A 1  109 ? 28.10816  -8.18728  25.54879  1.000 20.36185 ? 106 CYS A CA  1 
ATOM   848  C C   . CYS A 1  109 ? 26.79958  -8.29919  26.31744  1.000 22.26642 ? 106 CYS A C   1 
ATOM   849  O O   . CYS A 1  109 ? 26.38350  -7.35040  26.99145  1.000 22.69679 ? 106 CYS A O   1 
ATOM   850  C CB  . CYS A 1  109 ? 29.23008  -7.67850  26.45030  1.000 22.87234 ? 106 CYS A CB  1 
ATOM   851  S SG  . CYS A 1  109 ? 29.71166  -8.84726  27.74584  1.000 26.58562 ? 106 CYS A SG  1 
ATOM   852  N N   . LEU A 1  110 ? 26.15373  -9.45400  26.21110  1.000 23.70183 ? 107 LEU A N   1 
ATOM   853  C CA  . LEU A 1  110 ? 24.91048  -9.71414  26.92090  1.000 26.18824 ? 107 LEU A CA  1 
ATOM   854  C C   . LEU A 1  110 ? 25.22747  -10.41662 28.23516  1.000 25.66493 ? 107 LEU A C   1 
ATOM   855  O O   . LEU A 1  110 ? 25.80534  -11.50913 28.23719  1.000 23.72202 ? 107 LEU A O   1 
ATOM   856  C CB  . LEU A 1  110 ? 23.96839  -10.56187 26.06740  1.000 20.56982 ? 107 LEU A CB  1 
ATOM   857  C CG  . LEU A 1  110 ? 22.77749  -11.18131 26.80210  1.000 26.87857 ? 107 LEU A CG  1 
ATOM   858  C CD1 . LEU A 1  110 ? 21.83458  -10.09849 27.30543  1.000 18.10659 ? 107 LEU A CD1 1 
ATOM   859  C CD2 . LEU A 1  110 ? 22.04349  -12.16673 25.90421  1.000 26.03160 ? 107 LEU A CD2 1 
ATOM   860  N N   . VAL A 1  111 ? 24.86301  -9.78554  29.34590  1.000 21.48915 ? 108 VAL A N   1 
ATOM   861  C CA  . VAL A 1  111 ? 24.99184  -10.37602 30.67237  1.000 25.03299 ? 108 VAL A CA  1 
ATOM   862  C C   . VAL A 1  111 ? 23.58491  -10.70445 31.15087  1.000 26.31147 ? 108 VAL A C   1 
ATOM   863  O O   . VAL A 1  111 ? 22.81185  -9.80377  31.49872  1.000 21.54306 ? 108 VAL A O   1 
ATOM   864  C CB  . VAL A 1  111 ? 25.71591  -9.44244  31.65076  1.000 21.94339 ? 108 VAL A CB  1 
ATOM   865  C CG1 . VAL A 1  111 ? 26.02717  -10.17840 32.93945  1.000 21.72007 ? 108 VAL A CG1 1 
ATOM   866  C CG2 . VAL A 1  111 ? 26.99689  -8.90607  31.02048  1.000 20.63198 ? 108 VAL A CG2 1 
ATOM   867  N N   . ASP A 1  112 ? 23.25051  -11.99141 31.16288  1.000 26.41021 ? 109 ASP A N   1 
ATOM   868  C CA  . ASP A 1  112 ? 21.90896  -12.46964 31.45794  1.000 28.04535 ? 109 ASP A CA  1 
ATOM   869  C C   . ASP A 1  112 ? 21.86382  -13.11609 32.83711  1.000 26.97490 ? 109 ASP A C   1 
ATOM   870  O O   . ASP A 1  112 ? 22.89231  -13.49177 33.40704  1.000 22.95326 ? 109 ASP A O   1 
ATOM   871  C CB  . ASP A 1  112 ? 21.44754  -13.47210 30.39178  1.000 25.28137 ? 109 ASP A CB  1 
ATOM   872  C CG  . ASP A 1  112 ? 19.93743  -13.51099 30.23307  1.000 30.77823 ? 109 ASP A CG  1 
ATOM   873  O OD1 . ASP A 1  112 ? 19.22804  -12.85004 31.02108  1.000 27.22713 ? 109 ASP A OD1 1 
ATOM   874  O OD2 . ASP A 1  112 ? 19.45918  -14.20458 29.31106  1.000 39.19270 ? 109 ASP A OD2 1 
ATOM   875  N N   . ASN A 1  113 ? 20.64413  -13.23981 33.36610  1.000 25.94185 ? 110 ASN A N   1 
ATOM   876  C CA  . ASN A 1  113 ? 20.39770  -13.85464 34.67289  1.000 29.60272 ? 110 ASN A CA  1 
ATOM   877  C C   . ASN A 1  113 ? 21.17162  -13.13622 35.77951  1.000 25.67357 ? 110 ASN A C   1 
ATOM   878  O O   . ASN A 1  113 ? 21.88476  -13.75156 36.57453  1.000 28.29116 ? 110 ASN A O   1 
ATOM   879  C CB  . ASN A 1  113 ? 20.73128  -15.35012 34.64877  1.000 28.77057 ? 110 ASN A CB  1 
ATOM   880  C CG  . ASN A 1  113 ? 20.20996  -16.08518 35.87306  1.000 37.91310 ? 110 ASN A CG  1 
ATOM   881  O OD1 . ASN A 1  113 ? 19.05161  -15.92858 36.25754  1.000 36.65733 ? 110 ASN A OD1 1 
ATOM   882  N ND2 . ASN A 1  113 ? 21.06901  -16.88576 36.49531  1.000 31.84954 ? 110 ASN A ND2 1 
ATOM   883  N N   . ILE A 1  114 ? 21.02568  -11.81620 35.82709  1.000 26.15262 ? 111 ILE A N   1 
ATOM   884  C CA  . ILE A 1  114 ? 21.70781  -10.99659 36.82280  1.000 23.13210 ? 111 ILE A CA  1 
ATOM   885  C C   . ILE A 1  114 ? 20.81456  -10.86165 38.04804  1.000 26.57213 ? 111 ILE A C   1 
ATOM   886  O O   . ILE A 1  114 ? 19.70679  -10.32046 37.96179  1.000 21.93534 ? 111 ILE A O   1 
ATOM   887  C CB  . ILE A 1  114 ? 22.06323  -9.61087  36.26493  1.000 23.28958 ? 111 ILE A CB  1 
ATOM   888  C CG1 . ILE A 1  114 ? 22.91083  -9.72219  34.99912  1.000 23.44387 ? 111 ILE A CG1 1 
ATOM   889  C CG2 . ILE A 1  114 ? 22.78945  -8.78616  37.32237  1.000 20.80892 ? 111 ILE A CG2 1 
ATOM   890  C CD1 . ILE A 1  114 ? 23.24361  -8.37420  34.39666  1.000 21.00568 ? 111 ILE A CD1 1 
ATOM   891  N N   . PHE A 1  115 ? 21.29571  -11.34512 39.18894  1.000 23.42053 ? 112 PHE A N   1 
ATOM   892  C CA  . PHE A 1  115 ? 20.66856  -11.00244 40.45840  1.000 29.66303 ? 112 PHE A CA  1 
ATOM   893  C C   . PHE A 1  115 ? 21.64989  -11.19937 41.60566  1.000 27.95768 ? 112 PHE A C   1 
ATOM   894  O O   . PHE A 1  115 ? 22.28589  -12.25661 41.70420  1.000 26.10229 ? 112 PHE A O   1 
ATOM   895  C CB  . PHE A 1  115 ? 19.40271  -11.81990 40.71043  1.000 24.12027 ? 112 PHE A CB  1 
ATOM   896  C CG  . PHE A 1  115 ? 18.45526  -11.15430 41.65917  1.000 29.13353 ? 112 PHE A CG  1 
ATOM   897  C CD1 . PHE A 1  115 ? 17.54447  -10.21719 41.20119  1.000 24.50021 ? 112 PHE A CD1 1 
ATOM   898  C CD2 . PHE A 1  115 ? 18.50110  -11.43321 43.01558  1.000 25.55468 ? 112 PHE A CD2 1 
ATOM   899  C CE1 . PHE A 1  115 ? 16.68139  -9.58551  42.07624  1.000 30.98102 ? 112 PHE A CE1 1 
ATOM   900  C CE2 . PHE A 1  115 ? 17.64063  -10.80478 43.89548  1.000 26.42391 ? 112 PHE A CE2 1 
ATOM   901  C CZ  . PHE A 1  115 ? 16.73010  -9.88030  43.42581  1.000 27.38835 ? 112 PHE A CZ  1 
ATOM   902  N N   . PRO A 1  116 ? 21.79895  -10.20919 42.50017  1.000 29.17808 ? 113 PRO A N   1 
ATOM   903  C CA  . PRO A 1  116 ? 21.11371  -8.90824  42.49864  1.000 26.49192 ? 113 PRO A CA  1 
ATOM   904  C C   . PRO A 1  116 ? 21.61506  -7.97734  41.38539  1.000 27.38101 ? 113 PRO A C   1 
ATOM   905  O O   . PRO A 1  116 ? 22.65110  -8.27259  40.78621  1.000 28.27468 ? 113 PRO A O   1 
ATOM   906  C CB  . PRO A 1  116 ? 21.44881  -8.34650  43.88495  1.000 27.95737 ? 113 PRO A CB  1 
ATOM   907  C CG  . PRO A 1  116 ? 22.74509  -8.97090  44.23109  1.000 32.12562 ? 113 PRO A CG  1 
ATOM   908  C CD  . PRO A 1  116 ? 22.68523  -10.35833 43.66762  1.000 29.19538 ? 113 PRO A CD  1 
ATOM   909  N N   . PRO A 1  117 ? 20.89229  -6.87500  41.10332  1.000 27.87079 ? 114 PRO A N   1 
ATOM   910  C CA  . PRO A 1  117 ? 21.31967  -5.99662  39.98894  1.000 25.11560 ? 114 PRO A CA  1 
ATOM   911  C C   . PRO A 1  117 ? 22.51957  -5.13128  40.35638  1.000 22.94895 ? 114 PRO A C   1 
ATOM   912  O O   . PRO A 1  117 ? 22.45367  -3.90192  40.46437  1.000 25.65080 ? 114 PRO A O   1 
ATOM   913  C CB  . PRO A 1  117 ? 20.05623  -5.16983  39.70854  1.000 25.68176 ? 114 PRO A CB  1 
ATOM   914  C CG  . PRO A 1  117 ? 19.02411  -5.57407  40.73763  1.000 29.70982 ? 114 PRO A CG  1 
ATOM   915  C CD  . PRO A 1  117 ? 19.71325  -6.33812  41.80089  1.000 23.92394 ? 114 PRO A CD  1 
ATOM   916  N N   . VAL A 1  118 ? 23.65675  -5.79028  40.56570  1.000 25.19189 ? 115 VAL A N   1 
ATOM   917  C CA  . VAL A 1  118 ? 24.93120  -5.12413  40.81283  1.000 29.92143 ? 115 VAL A CA  1 
ATOM   918  C C   . VAL A 1  118 ? 25.97854  -5.83880  39.97369  1.000 23.78208 ? 115 VAL A C   1 
ATOM   919  O O   . VAL A 1  118 ? 26.23500  -7.02902  40.18442  1.000 26.32305 ? 115 VAL A O   1 
ATOM   920  C CB  . VAL A 1  118 ? 25.33198  -5.14458  42.29898  1.000 29.06052 ? 115 VAL A CB  1 
ATOM   921  C CG1 . VAL A 1  118 ? 26.68681  -4.47920  42.48955  1.000 25.85275 ? 115 VAL A CG1 1 
ATOM   922  C CG2 . VAL A 1  118 ? 24.26967  -4.46386  43.15718  1.000 25.19391 ? 115 VAL A CG2 1 
ATOM   923  N N   . VAL A 1  119 ? 26.57987  -5.12778  39.02119  1.000 26.29236 ? 116 VAL A N   1 
ATOM   924  C CA  . VAL A 1  119 ? 27.49818  -5.75831  38.08213  1.000 27.99415 ? 116 VAL A CA  1 
ATOM   925  C C   . VAL A 1  119 ? 28.47818  -4.72021  37.55493  1.000 26.90297 ? 116 VAL A C   1 
ATOM   926  O O   . VAL A 1  119 ? 28.17110  -3.52767  37.47063  1.000 27.04715 ? 116 VAL A O   1 
ATOM   927  C CB  . VAL A 1  119 ? 26.72904  -6.44786  36.92657  1.000 27.99122 ? 116 VAL A CB  1 
ATOM   928  C CG1 . VAL A 1  119 ? 26.23639  -5.42250  35.90988  1.000 28.16349 ? 116 VAL A CG1 1 
ATOM   929  C CG2 . VAL A 1  119 ? 27.59228  -7.51051  36.25956  1.000 22.98613 ? 116 VAL A CG2 1 
ATOM   930  N N   . ASN A 1  120 ? 29.67795  -5.18798  37.22287  1.000 25.92918 ? 117 ASN A N   1 
ATOM   931  C CA  . ASN A 1  120 ? 30.67512  -4.40998  36.50367  1.000 25.06618 ? 117 ASN A CA  1 
ATOM   932  C C   . ASN A 1  120 ? 30.92191  -5.08443  35.16358  1.000 26.53978 ? 117 ASN A C   1 
ATOM   933  O O   . ASN A 1  120 ? 31.23005  -6.27906  35.11825  1.000 39.39582 ? 117 ASN A O   1 
ATOM   934  C CB  . ASN A 1  120 ? 31.98869  -4.31505  37.28441  1.000 28.25985 ? 117 ASN A CB  1 
ATOM   935  C CG  . ASN A 1  120 ? 31.86882  -3.49221  38.55187  1.000 31.42866 ? 117 ASN A CG  1 
ATOM   936  O OD1 . ASN A 1  120 ? 31.07558  -2.55419  38.63721  1.000 31.81364 ? 117 ASN A OD1 1 
ATOM   937  N ND2 . ASN A 1  120 ? 32.67263  -3.84469  39.54645  1.000 38.41095 ? 117 ASN A ND2 1 
ATOM   938  N N   . ILE A 1  121 ? 30.77729  -4.32957  34.07828  1.000 27.62271 ? 118 ILE A N   1 
ATOM   939  C CA  . ILE A 1  121 ? 31.02051  -4.83401  32.73091  1.000 28.48629 ? 118 ILE A CA  1 
ATOM   940  C C   . ILE A 1  121 ? 32.04659  -3.92741  32.07002  1.000 28.66781 ? 118 ILE A C   1 
ATOM   941  O O   . ILE A 1  121 ? 31.80097  -2.72700  31.89638  1.000 30.55391 ? 118 ILE A O   1 
ATOM   942  C CB  . ILE A 1  121 ? 29.73280  -4.90382  31.89514  1.000 24.54198 ? 118 ILE A CB  1 
ATOM   943  C CG1 . ILE A 1  121 ? 28.62393  -5.61091  32.67427  1.000 23.15006 ? 118 ILE A CG1 1 
ATOM   944  C CG2 . ILE A 1  121 ? 29.99675  -5.62934  30.58693  1.000 28.62472 ? 118 ILE A CG2 1 
ATOM   945  C CD1 . ILE A 1  121 ? 27.24392  -5.40250  32.09254  1.000 29.79243 ? 118 ILE A CD1 1 
ATOM   946  N N   . THR A 1  122 ? 33.19195  -4.49932  31.70433  1.000 22.10655 ? 119 THR A N   1 
ATOM   947  C CA  . THR A 1  122 ? 34.27894  -3.75843  31.08424  1.000 25.99937 ? 119 THR A CA  1 
ATOM   948  C C   . THR A 1  122 ? 34.74923  -4.49102  29.83579  1.000 30.24149 ? 119 THR A C   1 
ATOM   949  O O   . THR A 1  122 ? 34.51456  -5.69047  29.66555  1.000 30.11362 ? 119 THR A O   1 
ATOM   950  C CB  . THR A 1  122 ? 35.45928  -3.56679  32.04857  1.000 27.53081 ? 119 THR A CB  1 
ATOM   951  O OG1 . THR A 1  122 ? 35.86836  -4.84080  32.56153  1.000 30.50795 ? 119 THR A OG1 1 
ATOM   952  C CG2 . THR A 1  122 ? 35.06462  -2.66148  33.20676  1.000 26.94946 ? 119 THR A CG2 1 
ATOM   953  N N   . TRP A 1  123 ? 35.42402  -3.75040  28.96231  1.000 18.96756 ? 120 TRP A N   1 
ATOM   954  C CA  . TRP A 1  123 ? 35.94441  -4.28171  27.71270  1.000 28.97450 ? 120 TRP A CA  1 
ATOM   955  C C   . TRP A 1  123 ? 37.46607  -4.25727  27.72937  1.000 29.28504 ? 120 TRP A C   1 
ATOM   956  O O   . TRP A 1  123 ? 38.07786  -3.33189  28.27231  1.000 29.36958 ? 120 TRP A O   1 
ATOM   957  C CB  . TRP A 1  123 ? 35.43196  -3.47924  26.51220  1.000 22.58278 ? 120 TRP A CB  1 
ATOM   958  C CG  . TRP A 1  123 ? 33.97557  -3.67302  26.21792  1.000 28.62720 ? 120 TRP A CG  1 
ATOM   959  C CD1 . TRP A 1  123 ? 32.94292  -2.89514  26.65132  1.000 24.41212 ? 120 TRP A CD1 1 
ATOM   960  C CD2 . TRP A 1  123 ? 33.38965  -4.70772  25.41670  1.000 25.59005 ? 120 TRP A CD2 1 
ATOM   961  N NE1 . TRP A 1  123 ? 31.75088  -3.38048  26.17270  1.000 24.57168 ? 120 TRP A NE1 1 
ATOM   962  C CE2 . TRP A 1  123 ? 31.99704  -4.49336  25.41251  1.000 24.70252 ? 120 TRP A CE2 1 
ATOM   963  C CE3 . TRP A 1  123 ? 33.90698  -5.79500  24.70539  1.000 23.32736 ? 120 TRP A CE3 1 
ATOM   964  C CZ2 . TRP A 1  123 ? 31.11474  -5.32342  24.72215  1.000 20.00943 ? 120 TRP A CZ2 1 
ATOM   965  C CZ3 . TRP A 1  123 ? 33.02915  -6.61982  24.02270  1.000 28.12816 ? 120 TRP A CZ3 1 
ATOM   966  C CH2 . TRP A 1  123 ? 31.64795  -6.37908  24.03673  1.000 20.64723 ? 120 TRP A CH2 1 
ATOM   967  N N   . LEU A 1  124 ? 38.06876  -5.27977  27.13277  1.000 28.64228 ? 121 LEU A N   1 
ATOM   968  C CA  . LEU A 1  124 ? 39.50729  -5.34606  26.93194  1.000 28.67194 ? 121 LEU A CA  1 
ATOM   969  C C   . LEU A 1  124 ? 39.79303  -5.55130  25.45270  1.000 31.00349 ? 121 LEU A C   1 
ATOM   970  O O   . LEU A 1  124 ? 39.06645  -6.27708  24.76844  1.000 28.76764 ? 121 LEU A O   1 
ATOM   971  C CB  . LEU A 1  124 ? 40.13938  -6.48084  27.74545  1.000 28.35827 ? 121 LEU A CB  1 
ATOM   972  C CG  . LEU A 1  124 ? 40.01239  -6.40435  29.26770  1.000 33.36691 ? 121 LEU A CG  1 
ATOM   973  C CD1 . LEU A 1  124 ? 40.39445  -7.73367  29.89942  1.000 30.23756 ? 121 LEU A CD1 1 
ATOM   974  C CD2 . LEU A 1  124 ? 40.87135  -5.27907  29.81695  1.000 30.21457 ? 121 LEU A CD2 1 
ATOM   975  N N   . SER A 1  125 ? 40.84579  -4.90079  24.96188  1.000 33.68569 ? 122 SER A N   1 
ATOM   976  C CA  . SER A 1  125 ? 41.32277  -5.08192  23.59389  1.000 32.49076 ? 122 SER A CA  1 
ATOM   977  C C   . SER A 1  125 ? 42.81936  -5.35127  23.65637  1.000 37.03078 ? 122 SER A C   1 
ATOM   978  O O   . SER A 1  125 ? 43.59261  -4.47323  24.05405  1.000 32.93269 ? 122 SER A O   1 
ATOM   979  C CB  . SER A 1  125 ? 41.01978  -3.85986  22.72711  1.000 30.67229 ? 122 SER A CB  1 
ATOM   980  O OG  . SER A 1  125 ? 41.81431  -3.85676  21.55474  1.000 38.08700 ? 122 SER A OG  1 
ATOM   981  N N   . ASN A 1  126 ? 43.22055  -6.56339  23.26654  1.000 30.47133 ? 123 ASN A N   1 
ATOM   982  C CA  . ASN A 1  126 ? 44.61049  -7.00908  23.37069  1.000 37.58578 ? 123 ASN A CA  1 
ATOM   983  C C   . ASN A 1  126 ? 45.12638  -6.86005  24.79972  1.000 38.45388 ? 123 ASN A C   1 
ATOM   984  O O   . ASN A 1  126 ? 46.27550  -6.48113  25.03414  1.000 41.56893 ? 123 ASN A O   1 
ATOM   985  C CB  . ASN A 1  126 ? 45.51001  -6.26179  22.38314  1.000 36.66996 ? 123 ASN A CB  1 
ATOM   986  C CG  . ASN A 1  126 ? 45.17277  -6.56999  20.93767  1.000 39.96925 ? 123 ASN A CG  1 
ATOM   987  O OD1 . ASN A 1  126 ? 44.50005  -7.55733  20.64021  1.000 40.56299 ? 123 ASN A OD1 1 
ATOM   988  N ND2 . ASN A 1  126 ? 45.64472  -5.72584  20.02873  1.000 47.61103 ? 123 ASN A ND2 1 
ATOM   989  N N   . GLY A 1  127 ? 44.25970  -7.15620  25.76720  1.000 39.67078 ? 124 GLY A N   1 
ATOM   990  C CA  . GLY A 1  127 ? 44.61141  -7.06633  27.16762  1.000 36.98597 ? 124 GLY A CA  1 
ATOM   991  C C   . GLY A 1  127 ? 44.60951  -5.67040  27.75010  1.000 37.55060 ? 124 GLY A C   1 
ATOM   992  O O   . GLY A 1  127 ? 44.90485  -5.51705  28.94186  1.000 42.05580 ? 124 GLY A O   1 
ATOM   993  N N   . HIS A 1  128 ? 44.29174  -4.65154  26.95863  1.000 39.69262 ? 125 HIS A N   1 
ATOM   994  C CA  . HIS A 1  128 ? 44.25324  -3.27396  27.42348  1.000 33.71479 ? 125 HIS A CA  1 
ATOM   995  C C   . HIS A 1  128 ? 42.81632  -2.84178  27.68793  1.000 37.20014 ? 125 HIS A C   1 
ATOM   996  O O   . HIS A 1  128 ? 41.88654  -3.25638  26.99182  1.000 33.58210 ? 125 HIS A O   1 
ATOM   997  C CB  . HIS A 1  128 ? 44.88679  -2.33427  26.39672  1.000 35.62929 ? 125 HIS A CB  1 
ATOM   998  C CG  . HIS A 1  128 ? 46.25646  -2.74700  25.95541  1.000 45.89223 ? 125 HIS A CG  1 
ATOM   999  N ND1 . HIS A 1  128 ? 46.57196  -2.98292  24.63432  1.000 46.61810 ? 125 HIS A ND1 1 
ATOM   1000 C CD2 . HIS A 1  128 ? 47.39578  -2.95538  26.65699  1.000 45.14658 ? 125 HIS A CD2 1 
ATOM   1001 C CE1 . HIS A 1  128 ? 47.84489  -3.32400  24.54175  1.000 43.18028 ? 125 HIS A CE1 1 
ATOM   1002 N NE2 . HIS A 1  128 ? 48.36784  -3.31447  25.75466  1.000 41.84854 ? 125 HIS A NE2 1 
ATOM   1003 N N   . SER A 1  129 ? 42.64480  -1.99049  28.69613  1.000 35.71312 ? 126 SER A N   1 
ATOM   1004 C CA  . SER A 1  129 ? 41.32230  -1.47065  29.01703  1.000 31.91060 ? 126 SER A CA  1 
ATOM   1005 C C   . SER A 1  129 ? 40.84983  -0.50838  27.93458  1.000 38.11419 ? 126 SER A C   1 
ATOM   1006 O O   . SER A 1  129 ? 41.62886  0.29068   27.40684  1.000 41.23437 ? 126 SER A O   1 
ATOM   1007 C CB  . SER A 1  129 ? 41.34164  -0.76232  30.36973  1.000 43.83090 ? 126 SER A CB  1 
ATOM   1008 O OG  . SER A 1  129 ? 41.66858  0.60845   30.21572  1.000 52.88581 ? 126 SER A OG  1 
ATOM   1009 N N   . VAL A 1  130 ? 39.56255  -0.58587  27.60537  1.000 30.33533 ? 127 VAL A N   1 
ATOM   1010 C CA  . VAL A 1  130 ? 38.95704  0.24847   26.57428  1.000 31.46410 ? 127 VAL A CA  1 
ATOM   1011 C C   . VAL A 1  130 ? 37.77013  0.98152   27.17943  1.000 31.27745 ? 127 VAL A C   1 
ATOM   1012 O O   . VAL A 1  130 ? 36.86881  0.35342   27.74657  1.000 37.05171 ? 127 VAL A O   1 
ATOM   1013 C CB  . VAL A 1  130 ? 38.51899  -0.58056  25.35287  1.000 33.19583 ? 127 VAL A CB  1 
ATOM   1014 C CG1 . VAL A 1  130 ? 37.86067  0.31290   24.31229  1.000 31.73973 ? 127 VAL A CG1 1 
ATOM   1015 C CG2 . VAL A 1  130 ? 39.70844  -1.30088  24.75573  1.000 35.01518 ? 127 VAL A CG2 1 
ATOM   1016 N N   . THR A 1  131 ? 37.77401  2.30964   27.06001  1.000 29.08976 ? 128 THR A N   1 
ATOM   1017 C CA  . THR A 1  131 ? 36.66381  3.13653   27.50721  1.000 29.25945 ? 128 THR A CA  1 
ATOM   1018 C C   . THR A 1  131 ? 36.01816  3.94257   26.39203  1.000 30.41250 ? 128 THR A C   1 
ATOM   1019 O O   . THR A 1  131 ? 34.84432  4.30640   26.52021  1.000 27.75622 ? 128 THR A O   1 
ATOM   1020 C CB  . THR A 1  131 ? 37.11937  4.10543   28.61113  1.000 34.77058 ? 128 THR A CB  1 
ATOM   1021 O OG1 . THR A 1  131 ? 38.09645  5.00963   28.08228  1.000 40.37514 ? 128 THR A OG1 1 
ATOM   1022 C CG2 . THR A 1  131 ? 37.72435  3.33969   29.77898  1.000 38.01044 ? 128 THR A CG2 1 
ATOM   1023 N N   . GLU A 1  132 ? 36.74069  4.22808   25.31224  1.000 26.23680 ? 129 GLU A N   1 
ATOM   1024 C CA  . GLU A 1  132 ? 36.16774  4.95477   24.18871  1.000 31.81942 ? 129 GLU A CA  1 
ATOM   1025 C C   . GLU A 1  132 ? 35.16100  4.07857   23.45351  1.000 28.93053 ? 129 GLU A C   1 
ATOM   1026 O O   . GLU A 1  132 ? 35.42654  2.90400   23.18096  1.000 30.77570 ? 129 GLU A O   1 
ATOM   1027 C CB  . GLU A 1  132 ? 37.27560  5.40539   23.23725  1.000 32.04840 ? 129 GLU A CB  1 
ATOM   1028 C CG  . GLU A 1  132 ? 36.81542  6.31429   22.11077  1.000 39.81056 ? 129 GLU A CG  1 
ATOM   1029 C CD  . GLU A 1  132 ? 37.89691  6.53718   21.06970  1.000 52.99132 ? 129 GLU A CD  1 
ATOM   1030 O OE1 . GLU A 1  132 ? 38.02675  5.69787   20.15344  1.000 61.44614 ? 129 GLU A OE1 1 
ATOM   1031 O OE2 . GLU A 1  132 ? 38.62134  7.54974   21.17050  1.000 61.08479 ? 129 GLU A OE2 1 
ATOM   1032 N N   . GLY A 1  133 ? 34.00158  4.65117   23.13721  1.000 24.28772 ? 130 GLY A N   1 
ATOM   1033 C CA  . GLY A 1  133 ? 32.99323  3.92907   22.38757  1.000 30.76129 ? 130 GLY A CA  1 
ATOM   1034 C C   . GLY A 1  133 ? 32.23558  2.88131   23.16938  1.000 33.82155 ? 130 GLY A C   1 
ATOM   1035 O O   . GLY A 1  133 ? 31.61378  2.00399   22.56466  1.000 25.89159 ? 130 GLY A O   1 
ATOM   1036 N N   . VAL A 1  134 ? 32.26318  2.94671   24.49869  1.000 28.15848 ? 131 VAL A N   1 
ATOM   1037 C CA  . VAL A 1  134 ? 31.59020  1.97547   25.35429  1.000 27.00432 ? 131 VAL A CA  1 
ATOM   1038 C C   . VAL A 1  134 ? 30.31094  2.59764   25.89579  1.000 26.81742 ? 131 VAL A C   1 
ATOM   1039 O O   . VAL A 1  134 ? 30.31717  3.74098   26.36822  1.000 31.67372 ? 131 VAL A O   1 
ATOM   1040 C CB  . VAL A 1  134 ? 32.50462  1.51606   26.50342  1.000 27.10914 ? 131 VAL A CB  1 
ATOM   1041 C CG1 . VAL A 1  134 ? 31.73250  0.64037   27.48570  1.000 25.61207 ? 131 VAL A CG1 1 
ATOM   1042 C CG2 . VAL A 1  134 ? 33.71454  0.77382   25.95707  1.000 29.25095 ? 131 VAL A CG2 1 
ATOM   1043 N N   . SER A 1  135 ? 29.21329  1.84894   25.82265  1.000 30.63665 ? 132 SER A N   1 
ATOM   1044 C CA  . SER A 1  135 ? 27.95534  2.25185   26.43404  1.000 28.66484 ? 132 SER A CA  1 
ATOM   1045 C C   . SER A 1  135 ? 27.23323  0.99804   26.90408  1.000 28.11951 ? 132 SER A C   1 
ATOM   1046 O O   . SER A 1  135 ? 27.66668  -0.12679  26.64088  1.000 26.20817 ? 132 SER A O   1 
ATOM   1047 C CB  . SER A 1  135 ? 27.08599  3.05790   25.46357  1.000 22.57825 ? 132 SER A CB  1 
ATOM   1048 O OG  . SER A 1  135 ? 26.78997  2.30287   24.30268  1.000 30.90112 ? 132 SER A OG  1 
ATOM   1049 N N   . GLU A 1  136 ? 26.12102  1.19828   27.60739  1.000 27.12250 ? 133 GLU A N   1 
ATOM   1050 C CA  . GLU A 1  136 ? 25.36112  0.06461   28.11251  1.000 27.63829 ? 133 GLU A CA  1 
ATOM   1051 C C   . GLU A 1  136 ? 23.91970  0.48133   28.36009  1.000 32.16252 ? 133 GLU A C   1 
ATOM   1052 O O   . GLU A 1  136 ? 23.60801  1.66480   28.51847  1.000 31.33998 ? 133 GLU A O   1 
ATOM   1053 C CB  . GLU A 1  136 ? 25.98208  -0.50702  29.39402  1.000 29.76124 ? 133 GLU A CB  1 
ATOM   1054 C CG  . GLU A 1  136 ? 25.91459  0.41769   30.59941  1.000 33.03814 ? 133 GLU A CG  1 
ATOM   1055 C CD  . GLU A 1  136 ? 26.56709  -0.18461  31.83297  1.000 45.35330 ? 133 GLU A CD  1 
ATOM   1056 O OE1 . GLU A 1  136 ? 27.66671  -0.76504  31.70544  1.000 40.33141 ? 133 GLU A OE1 1 
ATOM   1057 O OE2 . GLU A 1  136 ? 25.98072  -0.07737  32.93163  1.000 46.31498 ? 133 GLU A OE2 1 
ATOM   1058 N N   . THR A 1  137 ? 23.04516  -0.51901  28.38279  1.000 26.89957 ? 134 THR A N   1 
ATOM   1059 C CA  . THR A 1  137 ? 21.64922  -0.32780  28.72984  1.000 29.76790 ? 134 THR A CA  1 
ATOM   1060 C C   . THR A 1  137 ? 21.48270  -0.27279  30.24580  1.000 26.37974 ? 134 THR A C   1 
ATOM   1061 O O   . THR A 1  137 ? 22.41139  -0.53831  31.01280  1.000 23.56101 ? 134 THR A O   1 
ATOM   1062 C CB  . THR A 1  137 ? 20.79879  -1.46296  28.16726  1.000 28.45084 ? 134 THR A CB  1 
ATOM   1063 O OG1 . THR A 1  137 ? 21.01833  -2.64437  28.95090  1.000 22.84244 ? 134 THR A OG1 1 
ATOM   1064 C CG2 . THR A 1  137 ? 21.17247  -1.74458  26.71904  1.000 22.34805 ? 134 THR A CG2 1 
ATOM   1065 N N   . SER A 1  138 ? 20.27181  0.07023   30.67749  1.000 28.39603 ? 135 SER A N   1 
ATOM   1066 C CA  . SER A 1  138 ? 19.91342  -0.07699  32.07873  1.000 25.94152 ? 135 SER A CA  1 
ATOM   1067 C C   . SER A 1  138 ? 19.73453  -1.55811  32.40664  1.000 24.01179 ? 135 SER A C   1 
ATOM   1068 O O   . SER A 1  138 ? 19.81347  -2.43214  31.53850  1.000 22.66524 ? 135 SER A O   1 
ATOM   1069 C CB  . SER A 1  138 ? 18.63381  0.69787   32.39111  1.000 26.30124 ? 135 SER A CB  1 
ATOM   1070 O OG  . SER A 1  138 ? 18.73661  2.06046   32.01819  1.000 28.85965 ? 135 SER A OG  1 
ATOM   1071 N N   . PHE A 1  139 ? 19.48782  -1.84883  33.68004  1.000 23.89147 ? 136 PHE A N   1 
ATOM   1072 C CA  . PHE A 1  139 ? 19.04773  -3.18566  34.05381  1.000 23.84803 ? 136 PHE A CA  1 
ATOM   1073 C C   . PHE A 1  139 ? 17.65922  -3.42718  33.47340  1.000 23.95018 ? 136 PHE A C   1 
ATOM   1074 O O   . PHE A 1  139 ? 16.71084  -2.70388  33.79417  1.000 25.35213 ? 136 PHE A O   1 
ATOM   1075 C CB  . PHE A 1  139 ? 19.04022  -3.34490  35.57153  1.000 23.46549 ? 136 PHE A CB  1 
ATOM   1076 C CG  . PHE A 1  139 ? 20.41191  -3.44482  36.17753  1.000 26.32015 ? 136 PHE A CG  1 
ATOM   1077 C CD1 . PHE A 1  139 ? 21.15911  -4.60387  36.04079  1.000 21.78722 ? 136 PHE A CD1 1 
ATOM   1078 C CD2 . PHE A 1  139 ? 20.95255  -2.38451  36.88738  1.000 23.88183 ? 136 PHE A CD2 1 
ATOM   1079 C CE1 . PHE A 1  139 ? 22.41922  -4.70338  36.59805  1.000 24.29528 ? 136 PHE A CE1 1 
ATOM   1080 C CE2 . PHE A 1  139 ? 22.21374  -2.47819  37.44804  1.000 23.22500 ? 136 PHE A CE2 1 
ATOM   1081 C CZ  . PHE A 1  139 ? 22.94770  -3.63923  37.30240  1.000 29.24848 ? 136 PHE A CZ  1 
ATOM   1082 N N   . LEU A 1  140 ? 17.54434  -4.42414  32.60254  1.000 22.21307 ? 137 LEU A N   1 
ATOM   1083 C CA  . LEU A 1  140 ? 16.29779  -4.72562  31.91409  1.000 23.80231 ? 137 LEU A CA  1 
ATOM   1084 C C   . LEU A 1  140 ? 15.63822  -5.93947  32.55812  1.000 21.79309 ? 137 LEU A C   1 
ATOM   1085 O O   . LEU A 1  140 ? 16.31077  -6.91693  32.89975  1.000 19.58479 ? 137 LEU A O   1 
ATOM   1086 C CB  . LEU A 1  140 ? 16.55419  -4.97072  30.42407  1.000 28.48352 ? 137 LEU A CB  1 
ATOM   1087 C CG  . LEU A 1  140 ? 17.14308  -3.76766  29.67367  1.000 28.40507 ? 137 LEU A CG  1 
ATOM   1088 C CD1 . LEU A 1  140 ? 17.65823  -4.15971  28.30046  1.000 29.55734 ? 137 LEU A CD1 1 
ATOM   1089 C CD2 . LEU A 1  140 ? 16.12739  -2.64096  29.55454  1.000 30.91541 ? 137 LEU A CD2 1 
ATOM   1090 N N   . SER A 1  141 ? 14.31933  -5.87069  32.71983  1.000 24.84693 ? 138 SER A N   1 
ATOM   1091 C CA  . SER A 1  141 ? 13.60067  -6.82124  33.55464  1.000 24.98916 ? 138 SER A CA  1 
ATOM   1092 C C   . SER A 1  141 ? 13.38664  -8.15260  32.83750  1.000 25.70562 ? 138 SER A C   1 
ATOM   1093 O O   . SER A 1  141 ? 13.37045  -8.23675  31.60660  1.000 21.98365 ? 138 SER A O   1 
ATOM   1094 C CB  . SER A 1  141 ? 12.24929  -6.24412  33.98253  1.000 23.36836 ? 138 SER A CB  1 
ATOM   1095 O OG  . SER A 1  141 ? 11.33759  -6.21286  32.89542  1.000 21.22735 ? 138 SER A OG  1 
ATOM   1096 N N   . LYS A 1  142 ? 13.21598  -9.20275  33.64123  1.000 23.40509 ? 139 LYS A N   1 
ATOM   1097 C CA  . LYS A 1  142 ? 12.87051  -10.53404 33.16542  1.000 23.05905 ? 139 LYS A CA  1 
ATOM   1098 C C   . LYS A 1  142 ? 11.68545  -11.05846 33.96605  1.000 29.35490 ? 139 LYS A C   1 
ATOM   1099 O O   . LYS A 1  142 ? 11.43118  -10.62585 35.09373  1.000 22.41827 ? 139 LYS A O   1 
ATOM   1100 C CB  . LYS A 1  142 ? 14.05297  -11.50627 33.27932  1.000 21.07120 ? 139 LYS A CB  1 
ATOM   1101 C CG  . LYS A 1  142 ? 15.22105  -11.17438 32.36340  1.000 23.14241 ? 139 LYS A CG  1 
ATOM   1102 C CD  . LYS A 1  142 ? 16.47992  -11.91395 32.78432  1.000 23.22500 ? 139 LYS A CD  1 
ATOM   1103 C CE  . LYS A 1  142 ? 16.31897  -13.41984 32.63492  1.000 27.67359 ? 139 LYS A CE  1 
ATOM   1104 N NZ  . LYS A 1  142 ? 16.57962  -13.88657 31.24509  1.000 28.50333 ? 139 LYS A NZ  1 
ATOM   1105 N N   . SER A 1  143 ? 10.96227  -12.01191 33.37150  1.000 24.37356 ? 140 SER A N   1 
ATOM   1106 C CA  . SER A 1  143 ? 9.73907   -12.50656 33.99455  1.000 26.99529 ? 140 SER A CA  1 
ATOM   1107 C C   . SER A 1  143 ? 10.00756  -13.34044 35.24230  1.000 28.62474 ? 140 SER A C   1 
ATOM   1108 O O   . SER A 1  143 ? 9.09888   -13.50585 36.06232  1.000 24.69447 ? 140 SER A O   1 
ATOM   1109 C CB  . SER A 1  143 ? 8.91735   -13.31684 32.98841  1.000 22.18700 ? 140 SER A CB  1 
ATOM   1110 O OG  . SER A 1  143 ? 9.61562   -14.47125 32.55976  1.000 32.83304 ? 140 SER A OG  1 
ATOM   1111 N N   . ASP A 1  144 ? 11.21763  -13.87198 35.41201  1.000 25.50375 ? 141 ASP A N   1 
ATOM   1112 C CA  . ASP A 1  144 ? 11.57654  -14.52117 36.66591  1.000 21.66384 ? 141 ASP A CA  1 
ATOM   1113 C C   . ASP A 1  144 ? 12.17317  -13.54292 37.67036  1.000 28.08106 ? 141 ASP A C   1 
ATOM   1114 O O   . ASP A 1  144 ? 12.71582  -13.97276 38.69408  1.000 26.60692 ? 141 ASP A O   1 
ATOM   1115 C CB  . ASP A 1  144 ? 12.53110  -15.69948 36.41879  1.000 27.48593 ? 141 ASP A CB  1 
ATOM   1116 C CG  . ASP A 1  144 ? 13.87374  -15.28129 35.82333  1.000 28.10250 ? 141 ASP A CG  1 
ATOM   1117 O OD1 . ASP A 1  144 ? 14.19744  -14.07542 35.78015  1.000 27.65095 ? 141 ASP A OD1 1 
ATOM   1118 O OD2 . ASP A 1  144 ? 14.62223  -16.18689 35.40199  1.000 30.77277 ? 141 ASP A OD2 1 
ATOM   1119 N N   . HIS A 1  145 ? 12.09332  -12.24296 37.38385  1.000 24.55749 ? 142 HIS A N   1 
ATOM   1120 C CA  . HIS A 1  145 ? 12.47761  -11.14386 38.26428  1.000 24.01713 ? 142 HIS A CA  1 
ATOM   1121 C C   . HIS A 1  145 ? 13.98122  -11.04699 38.48381  1.000 26.89078 ? 142 HIS A C   1 
ATOM   1122 O O   . HIS A 1  145 ? 14.42433  -10.32054 39.38274  1.000 24.35611 ? 142 HIS A O   1 
ATOM   1123 C CB  . HIS A 1  145 ? 11.73645  -11.22694 39.60231  1.000 22.09677 ? 142 HIS A CB  1 
ATOM   1124 C CG  . HIS A 1  145 ? 10.26396  -11.43967 39.44292  1.000 25.02253 ? 142 HIS A CG  1 
ATOM   1125 N ND1 . HIS A 1  145 ? 9.48765   -10.65166 38.62032  1.000 20.38055 ? 142 HIS A ND1 1 
ATOM   1126 C CD2 . HIS A 1  145 ? 9.43126   -12.36781 39.97002  1.000 27.84691 ? 142 HIS A CD2 1 
ATOM   1127 C CE1 . HIS A 1  145 ? 8.23721   -11.07534 38.65961  1.000 22.78587 ? 142 HIS A CE1 1 
ATOM   1128 N NE2 . HIS A 1  145 ? 8.17558   -12.11484 39.47246  1.000 31.60966 ? 142 HIS A NE2 1 
ATOM   1129 N N   . SER A 1  146 ? 14.78026  -11.75214 37.68912  1.000 24.98658 ? 143 SER A N   1 
ATOM   1130 C CA  . SER A 1  146 ? 16.18874  -11.41631 37.54498  1.000 24.69975 ? 143 SER A CA  1 
ATOM   1131 C C   . SER A 1  146 ? 16.29439  -10.31544 36.48991  1.000 25.78741 ? 143 SER A C   1 
ATOM   1132 O O   . SER A 1  146 ? 15.28607  -9.79305  36.00510  1.000 20.14936 ? 143 SER A O   1 
ATOM   1133 C CB  . SER A 1  146 ? 17.00667  -12.65687 37.19247  1.000 26.31250 ? 143 SER A CB  1 
ATOM   1134 O OG  . SER A 1  146 ? 16.74700  -13.08803 35.86676  1.000 27.05481 ? 143 SER A OG  1 
ATOM   1135 N N   . PHE A 1  147 ? 17.51547  -9.94886  36.11334  1.000 19.22162 ? 144 PHE A N   1 
ATOM   1136 C CA  . PHE A 1  147 ? 17.73716  -8.88182  35.14981  1.000 24.44897 ? 144 PHE A CA  1 
ATOM   1137 C C   . PHE A 1  147 ? 18.74553  -9.33196  34.10258  1.000 25.81875 ? 144 PHE A C   1 
ATOM   1138 O O   . PHE A 1  147 ? 19.43324  -10.34536 34.25732  1.000 24.09066 ? 144 PHE A O   1 
ATOM   1139 C CB  . PHE A 1  147 ? 18.24079  -7.59964  35.83095  1.000 25.20240 ? 144 PHE A CB  1 
ATOM   1140 C CG  . PHE A 1  147 ? 17.24050  -6.96142  36.75156  1.000 22.76852 ? 144 PHE A CG  1 
ATOM   1141 C CD1 . PHE A 1  147 ? 17.17692  -7.32578  38.08549  1.000 27.81958 ? 144 PHE A CD1 1 
ATOM   1142 C CD2 . PHE A 1  147 ? 16.37569  -5.98536  36.28705  1.000 22.35767 ? 144 PHE A CD2 1 
ATOM   1143 C CE1 . PHE A 1  147 ? 16.25975  -6.73671  38.93781  1.000 24.03424 ? 144 PHE A CE1 1 
ATOM   1144 C CE2 . PHE A 1  147 ? 15.45724  -5.39206  37.13360  1.000 27.56127 ? 144 PHE A CE2 1 
ATOM   1145 C CZ  . PHE A 1  147 ? 15.40075  -5.76764  38.46154  1.000 24.85283 ? 144 PHE A CZ  1 
ATOM   1146 N N   . PHE A 1  148 ? 18.82134  -8.56106  33.02038  1.000 23.95514 ? 145 PHE A N   1 
ATOM   1147 C CA  . PHE A 1  148 ? 19.91638  -8.67587  32.07155  1.000 21.42544 ? 145 PHE A CA  1 
ATOM   1148 C C   . PHE A 1  148 ? 20.37013  -7.27569  31.68964  1.000 21.04066 ? 145 PHE A C   1 
ATOM   1149 O O   . PHE A 1  148 ? 19.63039  -6.29927  31.83112  1.000 24.30178 ? 145 PHE A O   1 
ATOM   1150 C CB  . PHE A 1  148 ? 19.54031  -9.50695  30.82845  1.000 20.39328 ? 145 PHE A CB  1 
ATOM   1151 C CG  . PHE A 1  148 ? 18.55760  -8.84144  29.89918  1.000 21.43881 ? 145 PHE A CG  1 
ATOM   1152 C CD1 . PHE A 1  148 ? 17.19505  -8.91328  30.13904  1.000 21.44500 ? 145 PHE A CD1 1 
ATOM   1153 C CD2 . PHE A 1  148 ? 18.99720  -8.18557  28.75823  1.000 25.65889 ? 145 PHE A CD2 1 
ATOM   1154 C CE1 . PHE A 1  148 ? 16.28926  -8.31972  29.27383  1.000 26.66073 ? 145 PHE A CE1 1 
ATOM   1155 C CE2 . PHE A 1  148 ? 18.09865  -7.59119  27.88772  1.000 22.11282 ? 145 PHE A CE2 1 
ATOM   1156 C CZ  . PHE A 1  148 ? 16.74192  -7.65835  28.14554  1.000 24.85247 ? 145 PHE A CZ  1 
ATOM   1157 N N   . LYS A 1  149 ? 21.61746  -7.18633  31.23657  1.000 23.18208 ? 146 LYS A N   1 
ATOM   1158 C CA  . LYS A 1  149 ? 22.22387  -5.91126  30.88945  1.000 22.23735 ? 146 LYS A CA  1 
ATOM   1159 C C   . LYS A 1  149 ? 23.14195  -6.12800  29.69919  1.000 19.50390 ? 146 LYS A C   1 
ATOM   1160 O O   . LYS A 1  149 ? 23.83110  -7.14763  29.61756  1.000 23.76290 ? 146 LYS A O   1 
ATOM   1161 C CB  . LYS A 1  149 ? 23.00359  -5.31802  32.07008  1.000 24.57713 ? 146 LYS A CB  1 
ATOM   1162 C CG  . LYS A 1  149 ? 23.51613  -3.90617  31.83087  1.000 25.58793 ? 146 LYS A CG  1 
ATOM   1163 C CD  . LYS A 1  149 ? 24.29710  -3.38935  33.02933  1.000 26.52322 ? 146 LYS A CD  1 
ATOM   1164 C CE  . LYS A 1  149 ? 23.48246  -2.39044  33.83194  1.000 29.01162 ? 146 LYS A CE  1 
ATOM   1165 N NZ  . LYS A 1  149 ? 23.82597  -0.98698  33.47522  1.000 36.04312 ? 146 LYS A NZ  1 
ATOM   1166 N N   . ILE A 1  150 ? 23.14200  -5.17103  28.77767  1.000 20.13784 ? 147 ILE A N   1 
ATOM   1167 C CA  . ILE A 1  150 ? 23.90727  -5.26925  27.54275  1.000 25.20936 ? 147 ILE A CA  1 
ATOM   1168 C C   . ILE A 1  150 ? 24.89265  -4.11219  27.48628  1.000 23.66140 ? 147 ILE A C   1 
ATOM   1169 O O   . ILE A 1  150 ? 24.51090  -2.95474  27.69211  1.000 23.43752 ? 147 ILE A O   1 
ATOM   1170 C CB  . ILE A 1  150 ? 22.99014  -5.26623  26.30715  1.000 23.04200 ? 147 ILE A CB  1 
ATOM   1171 C CG1 . ILE A 1  150 ? 22.07065  -6.48913  26.32422  1.000 24.32512 ? 147 ILE A CG1 1 
ATOM   1172 C CG2 . ILE A 1  150 ? 23.82030  -5.23429  25.04191  1.000 22.33206 ? 147 ILE A CG2 1 
ATOM   1173 C CD1 . ILE A 1  150 ? 20.84768  -6.34977  25.44067  1.000 22.92040 ? 147 ILE A CD1 1 
ATOM   1174 N N   . SER A 1  151 ? 26.15442  -4.42670  27.20873  1.000 22.67626 ? 148 SER A N   1 
ATOM   1175 C CA  . SER A 1  151 ? 27.19343  -3.42932  27.00160  1.000 21.76452 ? 148 SER A CA  1 
ATOM   1176 C C   . SER A 1  151 ? 27.64242  -3.46048  25.54619  1.000 18.98440 ? 148 SER A C   1 
ATOM   1177 O O   . SER A 1  151 ? 27.74235  -4.53321  24.94167  1.000 22.02495 ? 148 SER A O   1 
ATOM   1178 C CB  . SER A 1  151 ? 28.38541  -3.67705  27.92998  1.000 20.39993 ? 148 SER A CB  1 
ATOM   1179 O OG  . SER A 1  151 ? 29.38949  -2.69750  27.73934  1.000 25.21737 ? 148 SER A OG  1 
ATOM   1180 N N   . TYR A 1  152 ? 27.90666  -2.28208  24.98537  1.000 18.21062 ? 149 TYR A N   1 
ATOM   1181 C CA  . TYR A 1  152 ? 28.29100  -2.14553  23.58777  1.000 21.97438 ? 149 TYR A CA  1 
ATOM   1182 C C   . TYR A 1  152 ? 29.69404  -1.56702  23.47233  1.000 25.02635 ? 149 TYR A C   1 
ATOM   1183 O O   . TYR A 1  152 ? 30.12717  -0.76778  24.30781  1.000 24.57309 ? 149 TYR A O   1 
ATOM   1184 C CB  . TYR A 1  152 ? 27.31622  -1.24610  22.81741  1.000 18.68222 ? 149 TYR A CB  1 
ATOM   1185 C CG  . TYR A 1  152 ? 25.86521  -1.62032  22.98249  1.000 22.25907 ? 149 TYR A CG  1 
ATOM   1186 C CD1 . TYR A 1  152 ? 25.10595  -1.09102  24.01783  1.000 21.40485 ? 149 TYR A CD1 1 
ATOM   1187 C CD2 . TYR A 1  152 ? 25.25326  -2.50315  22.10325  1.000 21.56400 ? 149 TYR A CD2 1 
ATOM   1188 C CE1 . TYR A 1  152 ? 23.77943  -1.42928  24.17235  1.000 24.74797 ? 149 TYR A CE1 1 
ATOM   1189 C CE2 . TYR A 1  152 ? 23.92708  -2.84702  22.24884  1.000 21.62851 ? 149 TYR A CE2 1 
ATOM   1190 C CZ  . TYR A 1  152 ? 23.19549  -2.30717  23.28511  1.000 28.38075 ? 149 TYR A CZ  1 
ATOM   1191 O OH  . TYR A 1  152 ? 21.87477  -2.64706  23.43612  1.000 26.52892 ? 149 TYR A OH  1 
ATOM   1192 N N   . LEU A 1  153 ? 30.39592  -1.97415  22.41631  1.000 25.34249 ? 150 LEU A N   1 
ATOM   1193 C CA  . LEU A 1  153 ? 31.71330  -1.43403  22.09044  1.000 21.83215 ? 150 LEU A CA  1 
ATOM   1194 C C   . LEU A 1  153 ? 31.77351  -1.22629  20.58446  1.000 23.37311 ? 150 LEU A C   1 
ATOM   1195 O O   . LEU A 1  153 ? 31.87993  -2.19585  19.82674  1.000 23.64236 ? 150 LEU A O   1 
ATOM   1196 C CB  . LEU A 1  153 ? 32.83494  -2.36423  22.55626  1.000 20.27283 ? 150 LEU A CB  1 
ATOM   1197 C CG  . LEU A 1  153 ? 34.23411  -2.07816  21.99640  1.000 21.91770 ? 150 LEU A CG  1 
ATOM   1198 C CD1 . LEU A 1  153 ? 34.78774  -0.77302  22.54878  1.000 21.93194 ? 150 LEU A CD1 1 
ATOM   1199 C CD2 . LEU A 1  153 ? 35.18479  -3.22916  22.29355  1.000 24.83630 ? 150 LEU A CD2 1 
ATOM   1200 N N   . THR A 1  154 ? 31.68594  0.02716   20.14925  1.000 20.65073 ? 151 THR A N   1 
ATOM   1201 C CA  . THR A 1  154 ? 31.92276  0.33732   18.74727  1.000 24.49884 ? 151 THR A CA  1 
ATOM   1202 C C   . THR A 1  154 ? 33.40700  0.17743   18.44892  1.000 28.80904 ? 151 THR A C   1 
ATOM   1203 O O   . THR A 1  154 ? 34.25539  0.64421   19.21484  1.000 25.43185 ? 151 THR A O   1 
ATOM   1204 C CB  . THR A 1  154 ? 31.45737  1.75586   18.42255  1.000 28.25353 ? 151 THR A CB  1 
ATOM   1205 O OG1 . THR A 1  154 ? 32.18383  2.69517   19.22394  1.000 29.22276 ? 151 THR A OG1 1 
ATOM   1206 C CG2 . THR A 1  154 ? 29.96684  1.90463   18.70063  1.000 27.76815 ? 151 THR A CG2 1 
ATOM   1207 N N   . PHE A 1  155 ? 33.72516  -0.49652  17.34589  1.000 25.67681 ? 152 PHE A N   1 
ATOM   1208 C CA  . PHE A 1  155 ? 35.11033  -0.84712  17.07250  1.000 28.42329 ? 152 PHE A CA  1 
ATOM   1209 C C   . PHE A 1  155 ? 35.33147  -0.98504  15.57405  1.000 33.35273 ? 152 PHE A C   1 
ATOM   1210 O O   . PHE A 1  155 ? 34.38638  -1.08960  14.78715  1.000 27.29597 ? 152 PHE A O   1 
ATOM   1211 C CB  . PHE A 1  155 ? 35.50994  -2.14354  17.78939  1.000 24.18037 ? 152 PHE A CB  1 
ATOM   1212 C CG  . PHE A 1  155 ? 34.98432  -3.39141  17.13317  1.000 28.63280 ? 152 PHE A CG  1 
ATOM   1213 C CD1 . PHE A 1  155 ? 33.62484  -3.66243  17.11362  1.000 22.12100 ? 152 PHE A CD1 1 
ATOM   1214 C CD2 . PHE A 1  155 ? 35.85158  -4.29845  16.54480  1.000 27.58021 ? 152 PHE A CD2 1 
ATOM   1215 C CE1 . PHE A 1  155 ? 33.14005  -4.81110  16.51484  1.000 24.67977 ? 152 PHE A CE1 1 
ATOM   1216 C CE2 . PHE A 1  155 ? 35.37415  -5.44948  15.94480  1.000 22.12545 ? 152 PHE A CE2 1 
ATOM   1217 C CZ  . PHE A 1  155 ? 34.01650  -5.70562  15.92880  1.000 32.28326 ? 152 PHE A CZ  1 
ATOM   1218 N N   . LEU A 1  156 ? 36.60628  -0.97983  15.19448  1.000 32.50505 ? 153 LEU A N   1 
ATOM   1219 C CA  . LEU A 1  156 ? 37.02433  -1.18195  13.81338  1.000 29.81781 ? 153 LEU A CA  1 
ATOM   1220 C C   . LEU A 1  156 ? 37.63345  -2.57017  13.68707  1.000 27.55557 ? 153 LEU A C   1 
ATOM   1221 O O   . LEU A 1  156 ? 38.76112  -2.78804  14.15849  1.000 36.73620 ? 153 LEU A O   1 
ATOM   1222 C CB  . LEU A 1  156 ? 38.03417  -0.11267  13.39580  1.000 31.66665 ? 153 LEU A CB  1 
ATOM   1223 C CG  . LEU A 1  156 ? 38.04027  0.30686   11.92600  1.000 45.69751 ? 153 LEU A CG  1 
ATOM   1224 C CD1 . LEU A 1  156 ? 36.80826  1.13965   11.60367  1.000 45.80375 ? 153 LEU A CD1 1 
ATOM   1225 C CD2 . LEU A 1  156 ? 39.31362  1.07216   11.59710  1.000 36.96659 ? 153 LEU A CD2 1 
ATOM   1226 N N   . PRO A 1  157 ? 36.93580  -3.53289  13.08594  1.000 28.29645 ? 154 PRO A N   1 
ATOM   1227 C CA  . PRO A 1  157 ? 37.46363  -4.90227  13.01368  1.000 32.57961 ? 154 PRO A CA  1 
ATOM   1228 C C   . PRO A 1  157 ? 38.81635  -4.94635  12.31953  1.000 32.37069 ? 154 PRO A C   1 
ATOM   1229 O O   . PRO A 1  157 ? 39.00122  -4.38020  11.23978  1.000 33.30121 ? 154 PRO A O   1 
ATOM   1230 C CB  . PRO A 1  157 ? 36.39236  -5.65141  12.21228  1.000 30.87784 ? 154 PRO A CB  1 
ATOM   1231 C CG  . PRO A 1  157 ? 35.14622  -4.85860  12.41400  1.000 30.07934 ? 154 PRO A CG  1 
ATOM   1232 C CD  . PRO A 1  157 ? 35.58740  -3.42822  12.50807  1.000 31.94276 ? 154 PRO A CD  1 
ATOM   1233 N N   . SER A 1  158 ? 39.76480  -5.62796  12.95637  1.000 31.17173 ? 155 SER A N   1 
ATOM   1234 C CA  . SER A 1  158 ? 41.12656  -5.71410  12.45583  1.000 38.51345 ? 155 SER A CA  1 
ATOM   1235 C C   . SER A 1  158 ? 41.69103  -7.08568  12.78899  1.000 43.59405 ? 155 SER A C   1 
ATOM   1236 O O   . SER A 1  158 ? 41.34894  -7.68153  13.81412  1.000 37.40317 ? 155 SER A O   1 
ATOM   1237 C CB  . SER A 1  158 ? 42.01667  -4.61713  13.05094  1.000 36.57690 ? 155 SER A CB  1 
ATOM   1238 O OG  . SER A 1  158 ? 43.38755  -4.95131  12.92024  1.000 45.91101 ? 155 SER A OG  1 
ATOM   1239 N N   . ALA A 1  159 ? 42.56228  -7.58211  11.90884  1.000 42.97000 ? 156 ALA A N   1 
ATOM   1240 C CA  . ALA A 1  159 ? 43.23354  -8.85039  12.16039  1.000 44.80886 ? 156 ALA A CA  1 
ATOM   1241 C C   . ALA A 1  159 ? 44.22423  -8.76814  13.31290  1.000 41.07828 ? 156 ALA A C   1 
ATOM   1242 O O   . ALA A 1  159 ? 44.66293  -9.81262  13.80639  1.000 44.38657 ? 156 ALA A O   1 
ATOM   1243 C CB  . ALA A 1  159 ? 43.94815  -9.32700  10.89447  1.000 40.62089 ? 156 ALA A CB  1 
ATOM   1244 N N   . ASP A 1  160 ? 44.57633  -7.56136  13.75531  1.000 42.01893 ? 157 ASP A N   1 
ATOM   1245 C CA  . ASP A 1  160 ? 45.54347  -7.36586  14.82460  1.000 43.50709 ? 157 ASP A CA  1 
ATOM   1246 C C   . ASP A 1  160 ? 44.90228  -7.13671  16.18723  1.000 44.63135 ? 157 ASP A C   1 
ATOM   1247 O O   . ASP A 1  160 ? 45.62612  -7.06172  17.18535  1.000 41.36120 ? 157 ASP A O   1 
ATOM   1248 C CB  . ASP A 1  160 ? 46.45453  -6.17263  14.50055  1.000 48.34359 ? 157 ASP A CB  1 
ATOM   1249 C CG  . ASP A 1  160 ? 47.18713  -6.33387  13.18153  1.000 61.62041 ? 157 ASP A CG  1 
ATOM   1250 O OD1 . ASP A 1  160 ? 46.94753  -5.51802  12.26564  1.000 62.89054 ? 157 ASP A OD1 1 
ATOM   1251 O OD2 . ASP A 1  160 ? 48.00712  -7.26873  13.06220  1.000 65.35898 ? 157 ASP A OD2 1 
ATOM   1252 N N   . GLU A 1  161 ? 43.57815  -7.02294  16.26166  1.000 41.67832 ? 158 GLU A N   1 
ATOM   1253 C CA  . GLU A 1  161 ? 42.90254  -6.59704  17.47994  1.000 40.58630 ? 158 GLU A CA  1 
ATOM   1254 C C   . GLU A 1  161 ? 41.96853  -7.68976  17.97984  1.000 40.44605 ? 158 GLU A C   1 
ATOM   1255 O O   . GLU A 1  161 ? 41.20281  -8.26863  17.20170  1.000 39.27491 ? 158 GLU A O   1 
ATOM   1256 C CB  . GLU A 1  161 ? 42.13431  -5.29755  17.24663  1.000 49.00507 ? 158 GLU A CB  1 
ATOM   1257 C CG  . GLU A 1  161 ? 42.80428  -4.09084  17.87374  1.000 51.02811 ? 158 GLU A CG  1 
ATOM   1258 C CD  . GLU A 1  161 ? 41.80950  -3.04693  18.32738  1.000 63.84397 ? 158 GLU A CD  1 
ATOM   1259 O OE1 . GLU A 1  161 ? 40.93053  -2.67487  17.52159  1.000 70.34879 ? 158 GLU A OE1 1 
ATOM   1260 O OE2 . GLU A 1  161 ? 41.90229  -2.60344  19.49096  1.000 69.85882 ? 158 GLU A OE2 1 
ATOM   1261 N N   . ILE A 1  162 ? 42.03122  -7.95299  19.28277  1.000 39.17921 ? 159 ILE A N   1 
ATOM   1262 C CA  . ILE A 1  162 ? 41.36102  -9.08174  19.91900  1.000 37.58309 ? 159 ILE A CA  1 
ATOM   1263 C C   . ILE A 1  162 ? 40.69825  -8.57799  21.19831  1.000 36.24149 ? 159 ILE A C   1 
ATOM   1264 O O   . ILE A 1  162 ? 41.28205  -7.76989  21.92696  1.000 33.31235 ? 159 ILE A O   1 
ATOM   1265 C CB  . ILE A 1  162 ? 42.36912  -10.22114 20.20168  1.000 46.14938 ? 159 ILE A CB  1 
ATOM   1266 C CG1 . ILE A 1  162 ? 42.53627  -11.14528 18.98472  1.000 44.15589 ? 159 ILE A CG1 1 
ATOM   1267 C CG2 . ILE A 1  162 ? 42.00948  -10.98833 21.44622  1.000 44.75001 ? 159 ILE A CG2 1 
ATOM   1268 C CD1 . ILE A 1  162 ? 43.40915  -10.58105 17.87759  1.000 54.82370 ? 159 ILE A CD1 1 
ATOM   1269 N N   . TYR A 1  163 ? 39.47745  -9.04896  21.47672  1.000 28.36986 ? 160 TYR A N   1 
ATOM   1270 C CA  . TYR A 1  163 ? 38.64418  -8.44180  22.50830  1.000 30.17461 ? 160 TYR A CA  1 
ATOM   1271 C C   . TYR A 1  163 ? 38.17309  -9.45655  23.54210  1.000 30.23106 ? 160 TYR A C   1 
ATOM   1272 O O   . TYR A 1  163 ? 38.03357  -10.64971 23.26044  1.000 30.22141 ? 160 TYR A O   1 
ATOM   1273 C CB  . TYR A 1  163 ? 37.41658  -7.74897  21.89979  1.000 27.41560 ? 160 TYR A CB  1 
ATOM   1274 C CG  . TYR A 1  163 ? 37.76188  -6.73792  20.83550  1.000 31.77331 ? 160 TYR A CG  1 
ATOM   1275 C CD1 . TYR A 1  163 ? 38.02559  -5.41553  21.16675  1.000 32.31047 ? 160 TYR A CD1 1 
ATOM   1276 C CD2 . TYR A 1  163 ? 37.82944  -7.10594  19.49950  1.000 29.21098 ? 160 TYR A CD2 1 
ATOM   1277 C CE1 . TYR A 1  163 ? 38.34644  -4.48689  20.19433  1.000 36.96166 ? 160 TYR A CE1 1 
ATOM   1278 C CE2 . TYR A 1  163 ? 38.14949  -6.18625  18.52139  1.000 37.73682 ? 160 TYR A CE2 1 
ATOM   1279 C CZ  . TYR A 1  163 ? 38.40629  -4.87840  18.87386  1.000 34.54083 ? 160 TYR A CZ  1 
ATOM   1280 O OH  . TYR A 1  163 ? 38.72417  -3.96058  17.89979  1.000 49.81968 ? 160 TYR A OH  1 
ATOM   1281 N N   . ASP A 1  164 ? 37.91808  -8.94892  24.74786  1.000 25.96586 ? 161 ASP A N   1 
ATOM   1282 C CA  . ASP A 1  164 ? 37.31252  -9.70266  25.83532  1.000 28.44553 ? 161 ASP A CA  1 
ATOM   1283 C C   . ASP A 1  164 ? 36.26080  -8.83389  26.50621  1.000 31.43125 ? 161 ASP A C   1 
ATOM   1284 O O   . ASP A 1  164 ? 36.46038  -7.62712  26.67285  1.000 25.52022 ? 161 ASP A O   1 
ATOM   1285 C CB  . ASP A 1  164 ? 38.34748  -10.13545 26.88765  1.000 32.46251 ? 161 ASP A CB  1 
ATOM   1286 C CG  . ASP A 1  164 ? 39.28370  -11.21567 26.38575  1.000 37.68497 ? 161 ASP A CG  1 
ATOM   1287 O OD1 . ASP A 1  164 ? 38.84227  -12.37708 26.25704  1.000 40.61139 ? 161 ASP A OD1 1 
ATOM   1288 O OD2 . ASP A 1  164 ? 40.46638  -10.90413 26.13223  1.000 44.15770 ? 161 ASP A OD2 1 
ATOM   1289 N N   . CYS A 1  165 ? 35.14352  -9.44686  26.88644  1.000 25.20437 ? 162 CYS A N   1 
ATOM   1290 C CA  . CYS A 1  165 ? 34.18041  -8.82001  27.78044  1.000 26.91594 ? 162 CYS A CA  1 
ATOM   1291 C C   . CYS A 1  165 ? 34.40024  -9.36584  29.18448  1.000 26.87767 ? 162 CYS A C   1 
ATOM   1292 O O   . CYS A 1  165 ? 34.39292  -10.58406 29.38839  1.000 27.68978 ? 162 CYS A O   1 
ATOM   1293 C CB  . CYS A 1  165 ? 32.73915  -9.07363  27.33360  1.000 27.12225 ? 162 CYS A CB  1 
ATOM   1294 S SG  . CYS A 1  165 ? 31.53552  -8.18896  28.34969  1.000 35.92258 ? 162 CYS A SG  1 
ATOM   1295 N N   . LYS A 1  166 ? 34.60157  -8.46672  30.14445  1.000 24.60985 ? 163 LYS A N   1 
ATOM   1296 C CA  . LYS A 1  166 ? 34.94525  -8.83475  31.51304  1.000 28.19422 ? 163 LYS A CA  1 
ATOM   1297 C C   . LYS A 1  166 ? 33.82628  -8.38677  32.43976  1.000 23.65000 ? 163 LYS A C   1 
ATOM   1298 O O   . LYS A 1  166 ? 33.52375  -7.19113  32.52005  1.000 26.20581 ? 163 LYS A O   1 
ATOM   1299 C CB  . LYS A 1  166 ? 36.27617  -8.20561  31.93018  1.000 26.16624 ? 163 LYS A CB  1 
ATOM   1300 C CG  . LYS A 1  166 ? 36.53719  -8.22813  33.42631  1.000 32.12549 ? 163 LYS A CG  1 
ATOM   1301 C CD  . LYS A 1  166 ? 38.02761  -8.17210  33.72107  1.000 30.03456 ? 163 LYS A CD  1 
ATOM   1302 C CE  . LYS A 1  166 ? 38.32213  -7.25440  34.89634  1.000 44.04636 ? 163 LYS A CE  1 
ATOM   1303 N NZ  . LYS A 1  166 ? 39.56392  -7.65701  35.61361  1.000 46.12716 ? 163 LYS A NZ  1 
ATOM   1304 N N   . VAL A 1  167 ? 33.21463  -9.34001  33.13656  1.000 20.36061 ? 164 VAL A N   1 
ATOM   1305 C CA  . VAL A 1  167 ? 32.09901  -9.05965  34.03092  1.000 28.59190 ? 164 VAL A CA  1 
ATOM   1306 C C   . VAL A 1  167 ? 32.44906  -9.57422  35.42102  1.000 28.46270 ? 164 VAL A C   1 
ATOM   1307 O O   . VAL A 1  167 ? 32.98024  -10.68204 35.56943  1.000 24.34236 ? 164 VAL A O   1 
ATOM   1308 C CB  . VAL A 1  167 ? 30.77991  -9.66993  33.51134  1.000 33.84652 ? 164 VAL A CB  1 
ATOM   1309 C CG1 . VAL A 1  167 ? 31.01992  -10.46706 32.23644  1.000 34.81604 ? 164 VAL A CG1 1 
ATOM   1310 C CG2 . VAL A 1  167 ? 30.08145  -10.51545 34.57933  1.000 25.79419 ? 164 VAL A CG2 1 
ATOM   1311 N N   . GLU A 1  168 ? 32.18506  -8.75069  36.42932  1.000 30.51815 ? 165 GLU A N   1 
ATOM   1312 C CA  . GLU A 1  168 ? 32.34410  -9.12281  37.82613  1.000 32.90821 ? 165 GLU A CA  1 
ATOM   1313 C C   . GLU A 1  168 ? 30.97204  -9.13534  38.48053  1.000 29.40504 ? 165 GLU A C   1 
ATOM   1314 O O   . GLU A 1  168 ? 30.19974  -8.18322  38.32689  1.000 26.25223 ? 165 GLU A O   1 
ATOM   1315 C CB  . GLU A 1  168 ? 33.27290  -8.15188  38.55893  1.000 30.69092 ? 165 GLU A CB  1 
ATOM   1316 C CG  . GLU A 1  168 ? 34.53086  -7.77958  37.78850  1.000 40.13635 ? 165 GLU A CG  1 
ATOM   1317 C CD  . GLU A 1  168 ? 35.22867  -6.56593  38.37309  1.000 49.68774 ? 165 GLU A CD  1 
ATOM   1318 O OE1 . GLU A 1  168 ? 35.44395  -6.53754  39.60334  1.000 50.68703 ? 165 GLU A OE1 1 
ATOM   1319 O OE2 . GLU A 1  168 ? 35.55973  -5.63910  37.60319  1.000 58.47454 ? 165 GLU A OE2 1 
ATOM   1320 N N   . HIS A 1  169 ? 30.67056  -10.21646 39.19514  1.000 30.68868 ? 166 HIS A N   1 
ATOM   1321 C CA  . HIS A 1  169 ? 29.40644  -10.35253 39.90091  1.000 33.53051 ? 166 HIS A CA  1 
ATOM   1322 C C   . HIS A 1  169 ? 29.62734  -11.23990 41.11618  1.000 32.28780 ? 166 HIS A C   1 
ATOM   1323 O O   . HIS A 1  169 ? 30.45367  -12.15570 41.08818  1.000 30.52475 ? 166 HIS A O   1 
ATOM   1324 C CB  . HIS A 1  169 ? 28.31117  -10.93568 38.99674  1.000 25.06903 ? 166 HIS A CB  1 
ATOM   1325 C CG  . HIS A 1  169 ? 26.93936  -10.87573 39.59438  1.000 30.75940 ? 166 HIS A CG  1 
ATOM   1326 N ND1 . HIS A 1  169 ? 26.42371  -11.88480 40.37836  1.000 30.54805 ? 166 HIS A ND1 1 
ATOM   1327 C CD2 . HIS A 1  169 ? 25.97814  -9.92456  39.52678  1.000 27.66209 ? 166 HIS A CD2 1 
ATOM   1328 C CE1 . HIS A 1  169 ? 25.20446  -11.55840 40.76851  1.000 30.49574 ? 166 HIS A CE1 1 
ATOM   1329 N NE2 . HIS A 1  169 ? 24.91019  -10.37295 40.26592  1.000 30.36271 ? 166 HIS A NE2 1 
ATOM   1330 N N   . TRP A 1  170 ? 28.87794  -10.95793 42.18641  1.000 30.43302 ? 167 TRP A N   1 
ATOM   1331 C CA  . TRP A 1  170 ? 29.05188  -11.70470 43.42954  1.000 32.59352 ? 167 TRP A CA  1 
ATOM   1332 C C   . TRP A 1  170 ? 28.75065  -13.18631 43.24669  1.000 36.08237 ? 167 TRP A C   1 
ATOM   1333 O O   . TRP A 1  170 ? 29.31879  -14.02604 43.95410  1.000 34.92471 ? 167 TRP A O   1 
ATOM   1334 C CB  . TRP A 1  170 ? 28.16879  -11.11053 44.52605  1.000 29.24138 ? 167 TRP A CB  1 
ATOM   1335 C CG  . TRP A 1  170 ? 28.49244  -9.68251  44.82956  1.000 30.18998 ? 167 TRP A CG  1 
ATOM   1336 C CD1 . TRP A 1  170 ? 29.72666  -9.09979  44.80726  1.000 34.66117 ? 167 TRP A CD1 1 
ATOM   1337 C CD2 . TRP A 1  170 ? 27.56889  -8.65205  45.19812  1.000 30.55651 ? 167 TRP A CD2 1 
ATOM   1338 N NE1 . TRP A 1  170 ? 29.62834  -7.77037  45.13954  1.000 29.54643 ? 167 TRP A NE1 1 
ATOM   1339 C CE2 . TRP A 1  170 ? 28.31414  -7.47037  45.38409  1.000 31.21281 ? 167 TRP A CE2 1 
ATOM   1340 C CE3 . TRP A 1  170 ? 26.18421  -8.61307  45.38785  1.000 31.26731 ? 167 TRP A CE3 1 
ATOM   1341 C CZ2 . TRP A 1  170 ? 27.72148  -6.26407  45.75140  1.000 34.90984 ? 167 TRP A CZ2 1 
ATOM   1342 C CZ3 . TRP A 1  170 ? 25.59818  -7.41427  45.75279  1.000 29.67019 ? 167 TRP A CZ3 1 
ATOM   1343 C CH2 . TRP A 1  170 ? 26.36607  -6.25680  45.93132  1.000 29.92676 ? 167 TRP A CH2 1 
ATOM   1344 N N   . GLY A 1  171 ? 27.87070  -13.52815 42.30693  1.000 34.27018 ? 168 GLY A N   1 
ATOM   1345 C CA  . GLY A 1  171 ? 27.61493  -14.91671 41.97841  1.000 30.82828 ? 168 GLY A CA  1 
ATOM   1346 C C   . GLY A 1  171 ? 28.75436  -15.63014 41.28439  1.000 35.62761 ? 168 GLY A C   1 
ATOM   1347 O O   . GLY A 1  171 ? 28.64899  -16.83429 41.03320  1.000 36.73167 ? 168 GLY A O   1 
ATOM   1348 N N   . LEU A 1  172 ? 29.83588  -14.92434 40.96553  1.000 32.92724 ? 169 LEU A N   1 
ATOM   1349 C CA  . LEU A 1  172 ? 31.01010  -15.50532 40.33063  1.000 40.04169 ? 169 LEU A CA  1 
ATOM   1350 C C   . LEU A 1  172 ? 32.16313  -15.53133 41.32370  1.000 38.46799 ? 169 LEU A C   1 
ATOM   1351 O O   . LEU A 1  172 ? 32.43769  -14.52589 41.98787  1.000 35.36327 ? 169 LEU A O   1 
ATOM   1352 C CB  . LEU A 1  172 ? 31.41555  -14.70883 39.08843  1.000 37.22460 ? 169 LEU A CB  1 
ATOM   1353 C CG  . LEU A 1  172 ? 30.41353  -14.60204 37.93953  1.000 38.43904 ? 169 LEU A CG  1 
ATOM   1354 C CD1 . LEU A 1  172 ? 30.89021  -13.56895 36.93025  1.000 30.28812 ? 169 LEU A CD1 1 
ATOM   1355 C CD2 . LEU A 1  172 ? 30.21191  -15.95371 37.27564  1.000 35.76858 ? 169 LEU A CD2 1 
ATOM   1356 N N   . ASP A 1  173 ? 32.83614  -16.68065 41.42093  1.000 41.46285 ? 170 ASP A N   1 
ATOM   1357 C CA  . ASP A 1  173 ? 34.05523  -16.76301 42.21750  1.000 51.82069 ? 170 ASP A CA  1 
ATOM   1358 C C   . ASP A 1  173 ? 35.18498  -15.94097 41.61626  1.000 48.19925 ? 170 ASP A C   1 
ATOM   1359 O O   . ASP A 1  173 ? 36.11073  -15.55564 42.33831  1.000 51.42005 ? 170 ASP A O   1 
ATOM   1360 C CB  . ASP A 1  173 ? 34.51266  -18.21775 42.34855  1.000 52.49889 ? 170 ASP A CB  1 
ATOM   1361 C CG  . ASP A 1  173 ? 33.42964  -19.12663 42.89108  1.000 62.27485 ? 170 ASP A CG  1 
ATOM   1362 O OD1 . ASP A 1  173 ? 32.70572  -18.70706 43.81731  1.000 66.54407 ? 170 ASP A OD1 1 
ATOM   1363 O OD2 . ASP A 1  173 ? 33.30462  -20.26395 42.38820  1.000 69.49206 ? 170 ASP A OD2 1 
ATOM   1364 N N   . GLU A 1  174 ? 35.11993  -15.66031 40.31963  1.000 46.25021 ? 171 GLU A N   1 
ATOM   1365 C CA  . GLU A 1  174 ? 36.20421  -15.07155 39.55501  1.000 53.36140 ? 171 GLU A CA  1 
ATOM   1366 C C   . GLU A 1  174 ? 35.62146  -14.12530 38.51975  1.000 46.56731 ? 171 GLU A C   1 
ATOM   1367 O O   . GLU A 1  174 ? 34.49522  -14.33367 38.05206  1.000 40.33175 ? 171 GLU A O   1 
ATOM   1368 C CB  . GLU A 1  174 ? 37.02511  -16.16186 38.84872  1.000 53.33777 ? 171 GLU A CB  1 
ATOM   1369 C CG  . GLU A 1  174 ? 38.50519  -16.16742 39.16152  1.000 57.28598 ? 171 GLU A CG  1 
ATOM   1370 C CD  . GLU A 1  174 ? 39.18443  -17.42335 38.64938  1.000 74.58428 ? 171 GLU A CD  1 
ATOM   1371 O OE1 . GLU A 1  174 ? 38.85269  -17.86201 37.52730  1.000 74.38916 ? 171 GLU A OE1 1 
ATOM   1372 O OE2 . GLU A 1  174 ? 40.04131  -17.97722 39.37015  1.000 76.56286 ? 171 GLU A OE2 1 
ATOM   1373 N N   . PRO A 1  175 ? 36.35276  -13.07534 38.14916  1.000 48.62204 ? 172 PRO A N   1 
ATOM   1374 C CA  . PRO A 1  175 ? 35.93068  -12.25638 37.00640  1.000 41.88543 ? 172 PRO A CA  1 
ATOM   1375 C C   . PRO A 1  175 ? 35.78562  -13.11773 35.76037  1.000 39.40138 ? 172 PRO A C   1 
ATOM   1376 O O   . PRO A 1  175 ? 36.66370  -13.91899 35.43297  1.000 43.30019 ? 172 PRO A O   1 
ATOM   1377 C CB  . PRO A 1  175 ? 37.06253  -11.23300 36.86582  1.000 42.54236 ? 172 PRO A CB  1 
ATOM   1378 C CG  . PRO A 1  175 ? 37.64619  -11.13721 38.24287  1.000 44.05715 ? 172 PRO A CG  1 
ATOM   1379 C CD  . PRO A 1  175 ? 37.54142  -12.52191 38.82089  1.000 36.82717 ? 172 PRO A CD  1 
ATOM   1380 N N   . LEU A 1  176 ? 34.65516  -12.96384 35.07722  1.000 32.07540 ? 173 LEU A N   1 
ATOM   1381 C CA  . LEU A 1  176 ? 34.33385  -13.76580 33.90371  1.000 35.06402 ? 173 LEU A CA  1 
ATOM   1382 C C   . LEU A 1  176 ? 34.75024  -13.01157 32.64846  1.000 32.33994 ? 173 LEU A C   1 
ATOM   1383 O O   . LEU A 1  176 ? 34.30329  -11.88236 32.42009  1.000 31.31434 ? 173 LEU A O   1 
ATOM   1384 C CB  . LEU A 1  176 ? 32.84335  -14.10014 33.85722  1.000 34.21138 ? 173 LEU A CB  1 
ATOM   1385 C CG  . LEU A 1  176 ? 32.47018  -15.24472 32.91309  1.000 39.29297 ? 173 LEU A CG  1 
ATOM   1386 C CD1 . LEU A 1  176 ? 33.36078  -16.45140 33.16424  1.000 43.35266 ? 173 LEU A CD1 1 
ATOM   1387 C CD2 . LEU A 1  176 ? 31.00220  -15.61675 33.05663  1.000 34.15287 ? 173 LEU A CD2 1 
ATOM   1388 N N   . LEU A 1  177 ? 35.60092  -13.63746 31.84142  1.000 32.63433 ? 174 LEU A N   1 
ATOM   1389 C CA  . LEU A 1  177 ? 36.07838  -13.06663 30.58980  1.000 28.30792 ? 174 LEU A CA  1 
ATOM   1390 C C   . LEU A 1  177 ? 35.51448  -13.88603 29.43845  1.000 34.06529 ? 174 LEU A C   1 
ATOM   1391 O O   . LEU A 1  177 ? 35.71494  -15.10415 29.38299  1.000 36.76404 ? 174 LEU A O   1 
ATOM   1392 C CB  . LEU A 1  177 ? 37.60674  -13.04766 30.53952  1.000 34.40451 ? 174 LEU A CB  1 
ATOM   1393 C CG  . LEU A 1  177 ? 38.30459  -11.78392 31.04684  1.000 29.47375 ? 174 LEU A CG  1 
ATOM   1394 C CD1 . LEU A 1  177 ? 38.24925  -11.71010 32.56661  1.000 39.25868 ? 174 LEU A CD1 1 
ATOM   1395 C CD2 . LEU A 1  177 ? 39.74311  -11.73324 30.55314  1.000 41.42329 ? 174 LEU A CD2 1 
ATOM   1396 N N   . LYS A 1  178 ? 34.80671  -13.22241 28.53062  1.000 28.45979 ? 175 LYS A N   1 
ATOM   1397 C CA  . LYS A 1  178 ? 34.24638  -13.86186 27.34799  1.000 32.46633 ? 175 LYS A CA  1 
ATOM   1398 C C   . LYS A 1  178 ? 34.98197  -13.34011 26.12214  1.000 30.02419 ? 175 LYS A C   1 
ATOM   1399 O O   . LYS A 1  178 ? 35.04146  -12.12651 25.89625  1.000 26.68010 ? 175 LYS A O   1 
ATOM   1400 C CB  . LYS A 1  178 ? 32.74411  -13.60665 27.24036  1.000 34.20526 ? 175 LYS A CB  1 
ATOM   1401 C CG  . LYS A 1  178 ? 31.89451  -14.79933 27.64844  1.000 46.64708 ? 175 LYS A CG  1 
ATOM   1402 C CD  . LYS A 1  178 ? 32.16242  -15.99646 26.74809  1.000 41.91243 ? 175 LYS A CD  1 
ATOM   1403 C CE  . LYS A 1  178 ? 31.27865  -17.17605 27.11834  1.000 41.24562 ? 175 LYS A CE  1 
ATOM   1404 N NZ  . LYS A 1  178 ? 31.26955  -17.41444 28.58893  1.000 50.30650 ? 175 LYS A NZ  1 
ATOM   1405 N N   . HIS A 1  179 ? 35.53050  -14.25842 25.33705  1.000 33.29725 ? 176 HIS A N   1 
ATOM   1406 C CA  . HIS A 1  179 ? 36.44828  -13.93110 24.25882  1.000 32.59971 ? 176 HIS A CA  1 
ATOM   1407 C C   . HIS A 1  179 ? 35.70790  -13.71995 22.94393  1.000 30.03715 ? 176 HIS A C   1 
ATOM   1408 O O   . HIS A 1  179 ? 34.66009  -14.32094 22.69436  1.000 38.98789 ? 176 HIS A O   1 
ATOM   1409 C CB  . HIS A 1  179 ? 37.47650  -15.05016 24.09930  1.000 32.49492 ? 176 HIS A CB  1 
ATOM   1410 C CG  . HIS A 1  179 ? 38.69071  -14.65009 23.32683  1.000 39.38516 ? 176 HIS A CG  1 
ATOM   1411 N ND1 . HIS A 1  179 ? 39.47682  -13.57680 23.68376  1.000 42.34132 ? 176 HIS A ND1 1 
ATOM   1412 C CD2 . HIS A 1  179 ? 39.25651  -15.18058 22.21741  1.000 40.75383 ? 176 HIS A CD2 1 
ATOM   1413 C CE1 . HIS A 1  179 ? 40.47596  -13.46466 22.82813  1.000 42.26320 ? 176 HIS A CE1 1 
ATOM   1414 N NE2 . HIS A 1  179 ? 40.36515  -14.42415 21.92780  1.000 40.37985 ? 176 HIS A NE2 1 
ATOM   1415 N N   . TRP A 1  180 ? 36.27087  -12.85819 22.09733  1.000 35.67259 ? 177 TRP A N   1 
ATOM   1416 C CA  . TRP A 1  180 ? 35.74976  -12.65672 20.75083  1.000 35.50707 ? 177 TRP A CA  1 
ATOM   1417 C C   . TRP A 1  180 ? 36.88005  -12.23064 19.82731  1.000 33.58799 ? 177 TRP A C   1 
ATOM   1418 O O   . TRP A 1  180 ? 37.61232  -11.28545 20.13547  1.000 29.90982 ? 177 TRP A O   1 
ATOM   1419 C CB  . TRP A 1  180 ? 34.63260  -11.60818 20.72577  1.000 29.11368 ? 177 TRP A CB  1 
ATOM   1420 C CG  . TRP A 1  180 ? 33.89175  -11.58876 19.42268  1.000 33.58840 ? 177 TRP A CG  1 
ATOM   1421 C CD1 . TRP A 1  180 ? 32.75818  -12.28315 19.11487  1.000 34.36534 ? 177 TRP A CD1 1 
ATOM   1422 C CD2 . TRP A 1  180 ? 34.24385  -10.85338 18.24303  1.000 33.19038 ? 177 TRP A CD2 1 
ATOM   1423 N NE1 . TRP A 1  180 ? 32.37782  -12.02017 17.82107  1.000 30.32331 ? 177 TRP A NE1 1 
ATOM   1424 C CE2 . TRP A 1  180 ? 33.27310  -11.14567 17.26387  1.000 34.75201 ? 177 TRP A CE2 1 
ATOM   1425 C CE3 . TRP A 1  180 ? 35.28085  -9.97184  17.92199  1.000 28.09879 ? 177 TRP A CE3 1 
ATOM   1426 C CZ2 . TRP A 1  180 ? 33.30849  -10.58824 15.98712  1.000 24.74168 ? 177 TRP A CZ2 1 
ATOM   1427 C CZ3 . TRP A 1  180 ? 35.31474  -9.42058  16.65193  1.000 32.14648 ? 177 TRP A CZ3 1 
ATOM   1428 C CH2 . TRP A 1  180 ? 34.33481  -9.73087  15.70138  1.000 29.22942 ? 177 TRP A CH2 1 
ATOM   1429 N N   . GLU A 1  181 ? 37.00804  -12.92226 18.69823  1.000 34.53857 ? 178 GLU A N   1 
ATOM   1430 C CA  . GLU A 1  181 ? 37.98134  -12.60472 17.66626  1.000 40.81852 ? 178 GLU A CA  1 
ATOM   1431 C C   . GLU A 1  181 ? 37.28786  -12.45189 16.32286  1.000 33.22249 ? 178 GLU A C   1 
ATOM   1432 O O   . GLU A 1  181 ? 36.26033  -13.08957 16.07166  1.000 32.76382 ? 178 GLU A O   1 
ATOM   1433 C CB  . GLU A 1  181 ? 39.05397  -13.69583 17.53570  1.000 35.02002 ? 178 GLU A CB  1 
ATOM   1434 C CG  . GLU A 1  181 ? 39.50059  -14.31747 18.83445  1.000 43.04387 ? 178 GLU A CG  1 
ATOM   1435 C CD  . GLU A 1  181 ? 40.92911  -14.81456 18.76743  1.000 39.41275 ? 178 GLU A CD  1 
ATOM   1436 O OE1 . GLU A 1  181 ? 41.31705  -15.36262 17.71376  1.000 51.69635 ? 178 GLU A OE1 1 
ATOM   1437 O OE2 . GLU A 1  181 ? 41.66348  -14.65805 19.76480  1.000 45.77637 ? 178 GLU A OE2 1 
ATOM   1438 N N   . PRO A 1  182 ? 37.82987  -11.61712 15.43920  1.000 36.63485 ? 179 PRO A N   1 
ATOM   1439 C CA  . PRO A 1  182 ? 37.36622  -11.62697 14.04810  1.000 41.08088 ? 179 PRO A CA  1 
ATOM   1440 C C   . PRO A 1  182 ? 37.75191  -12.93196 13.37074  1.000 42.95765 ? 179 PRO A C   1 
ATOM   1441 O O   . PRO A 1  182 ? 38.84766  -13.45955 13.57631  1.000 43.58559 ? 179 PRO A O   1 
ATOM   1442 C CB  . PRO A 1  182 ? 38.09032  -10.43032 13.41737  1.000 36.52863 ? 179 PRO A CB  1 
ATOM   1443 C CG  . PRO A 1  182 ? 38.55607  -9.59646  14.57637  1.000 43.02398 ? 179 PRO A CG  1 
ATOM   1444 C CD  . PRO A 1  182 ? 38.82530  -10.56171 15.68367  1.000 36.94797 ? 179 PRO A CD  1 
ATOM   1445 N N   . GLU A 1  183 ? 36.83459  -13.45461 12.56237  1.000 53.22596 ? 180 GLU A N   1 
ATOM   1446 C CA  . GLU A 1  183 ? 37.06181  -14.72556 11.88537  1.000 65.56677 ? 180 GLU A CA  1 
ATOM   1447 C C   . GLU A 1  183 ? 38.11470  -14.55949 10.79522  1.000 68.34921 ? 180 GLU A C   1 
ATOM   1448 O O   . GLU A 1  183 ? 37.94228  -13.75618 9.87203   1.000 66.67389 ? 180 GLU A O   1 
ATOM   1449 C CB  . GLU A 1  183 ? 35.75498  -15.24772 11.29459  1.000 64.65478 ? 180 GLU A CB  1 
ATOM   1450 C CG  . GLU A 1  183 ? 35.43020  -16.68242 11.67560  1.000 72.10163 ? 180 GLU A CG  1 
ATOM   1451 C CD  . GLU A 1  183 ? 34.02756  -17.08850 11.26744  1.000 89.49078 ? 180 GLU A CD  1 
ATOM   1452 O OE1 . GLU A 1  183 ? 33.65600  -16.85345 10.09825  1.000 95.40019 ? 180 GLU A OE1 1 
ATOM   1453 O OE2 . GLU A 1  183 ? 33.29657  -17.64313 12.11488  1.000 96.29156 ? 180 GLU A OE2 1 
ATOM   1454 N N   . THR A 1  184 ? 39.20179  -15.31838 10.90220  1.000 67.32704 ? 181 THR A N   1 
ATOM   1455 C CA  . THR A 1  184 ? 40.26249  -15.29311 9.90035   1.000 76.97364 ? 181 THR A CA  1 
ATOM   1456 C C   . THR A 1  184 ? 41.15166  -16.52826 10.01409  1.000 80.28180 ? 181 THR A C   1 
ATOM   1457 O O   . THR A 1  184 ? 40.66054  -17.65448 10.09384  1.000 81.35741 ? 181 THR A O   1 
ATOM   1458 C CB  . THR A 1  184 ? 41.13568  -14.02884 10.02635  1.000 75.23277 ? 181 THR A CB  1 
ATOM   1459 O OG1 . THR A 1  184 ? 41.71588  -13.71864 8.75319   1.000 76.11878 ? 181 THR A OG1 1 
ATOM   1460 C CG2 . THR A 1  184 ? 42.24435  -14.24145 11.04766  1.000 66.37065 ? 181 THR A CG2 1 
ATOM   1461 N N   . SER B 2  3   ? 31.28286  -11.77214 49.98855  1.000 55.73365 ? 3   SER B N   1 
ATOM   1462 C CA  . SER B 2  3   ? 30.09971  -11.29806 49.28036  1.000 51.41214 ? 3   SER B CA  1 
ATOM   1463 C C   . SER B 2  3   ? 29.19325  -10.49586 50.20775  1.000 43.12089 ? 3   SER B C   1 
ATOM   1464 O O   . SER B 2  3   ? 28.65792  -11.03526 51.17566  1.000 45.60731 ? 3   SER B O   1 
ATOM   1465 C CB  . SER B 2  3   ? 29.32818  -12.47335 48.67618  1.000 53.51813 ? 3   SER B CB  1 
ATOM   1466 O OG  . SER B 2  3   ? 28.02765  -12.07700 48.27487  1.000 54.93625 ? 3   SER B OG  1 
ATOM   1467 N N   . PRO B 2  4   ? 29.02728  -9.20846  49.91508  1.000 39.66069 ? 4   PRO B N   1 
ATOM   1468 C CA  . PRO B 2  4   ? 28.16547  -8.36621  50.75091  1.000 39.61173 ? 4   PRO B CA  1 
ATOM   1469 C C   . PRO B 2  4   ? 26.69841  -8.74624  50.61611  1.000 44.12261 ? 4   PRO B C   1 
ATOM   1470 O O   . PRO B 2  4   ? 26.27952  -9.43057  49.67954  1.000 43.47165 ? 4   PRO B O   1 
ATOM   1471 C CB  . PRO B 2  4   ? 28.42039  -6.94952  50.22301  1.000 36.62728 ? 4   PRO B CB  1 
ATOM   1472 C CG  . PRO B 2  4   ? 28.98979  -7.13625  48.86049  1.000 43.23467 ? 4   PRO B CG  1 
ATOM   1473 C CD  . PRO B 2  4   ? 29.72468  -8.43850  48.87174  1.000 40.17884 ? 4   PRO B CD  1 
ATOM   1474 N N   . GLU B 2  5   ? 25.91413  -8.27838  51.58198  1.000 42.18372 ? 5   GLU B N   1 
ATOM   1475 C CA  . GLU B 2  5   ? 24.49229  -8.57569  51.65294  1.000 43.06251 ? 5   GLU B CA  1 
ATOM   1476 C C   . GLU B 2  5   ? 23.68509  -7.51481  50.91445  1.000 38.64124 ? 5   GLU B C   1 
ATOM   1477 O O   . GLU B 2  5   ? 24.03498  -6.33141  50.90928  1.000 40.48058 ? 5   GLU B O   1 
ATOM   1478 C CB  . GLU B 2  5   ? 24.03630  -8.65645  53.11073  1.000 36.64983 ? 5   GLU B CB  1 
ATOM   1479 C CG  . GLU B 2  5   ? 23.06302  -9.78145  53.38809  1.000 43.05323 ? 5   GLU B CG  1 
ATOM   1480 C CD  . GLU B 2  5   ? 22.76119  -9.95097  54.86447  1.000 46.33551 ? 5   GLU B CD  1 
ATOM   1481 O OE1 . GLU B 2  5   ? 22.83424  -8.94897  55.60663  1.000 44.67802 ? 5   GLU B OE1 1 
ATOM   1482 O OE2 . GLU B 2  5   ? 22.44472  -11.08580 55.28141  1.000 51.44326 ? 5   GLU B OE2 1 
ATOM   1483 N N   . ASP B 2  6   ? 22.58965  -7.95012  50.29343  1.000 34.62942 ? 6   ASP B N   1 
ATOM   1484 C CA  . ASP B 2  6   ? 21.74559  -7.05862  49.51148  1.000 28.53162 ? 6   ASP B CA  1 
ATOM   1485 C C   . ASP B 2  6   ? 20.28534  -7.45429  49.66654  1.000 28.21241 ? 6   ASP B C   1 
ATOM   1486 O O   . ASP B 2  6   ? 19.94728  -8.64088  49.64247  1.000 29.53188 ? 6   ASP B O   1 
ATOM   1487 C CB  . ASP B 2  6   ? 22.13917  -7.08060  48.02961  1.000 27.86324 ? 6   ASP B CB  1 
ATOM   1488 C CG  . ASP B 2  6   ? 21.59138  -5.89386  47.26118  1.000 32.75000 ? 6   ASP B CG  1 
ATOM   1489 O OD1 . ASP B 2  6   ? 21.09336  -4.94120  47.89932  1.000 30.71525 ? 6   ASP B OD1 1 
ATOM   1490 O OD2 . ASP B 2  6   ? 21.66497  -5.91381  46.01446  1.000 28.67703 ? 6   ASP B OD2 1 
ATOM   1491 N N   . PHE B 2  7   ? 19.42772  -6.44964  49.82734  1.000 29.42836 ? 7   PHE B N   1 
ATOM   1492 C CA  . PHE B 2  7   ? 17.98377  -6.62712  49.89986  1.000 27.12009 ? 7   PHE B CA  1 
ATOM   1493 C C   . PHE B 2  7   ? 17.34853  -5.80855  48.78609  1.000 28.92553 ? 7   PHE B C   1 
ATOM   1494 O O   . PHE B 2  7   ? 17.62199  -4.61048  48.66338  1.000 28.12867 ? 7   PHE B O   1 
ATOM   1495 C CB  . PHE B 2  7   ? 17.43852  -6.19488  51.26403  1.000 27.20887 ? 7   PHE B CB  1 
ATOM   1496 C CG  . PHE B 2  7   ? 18.06601  -6.91553  52.42783  1.000 31.29414 ? 7   PHE B CG  1 
ATOM   1497 C CD1 . PHE B 2  7   ? 19.23548  -6.44446  53.00624  1.000 36.54680 ? 7   PHE B CD1 1 
ATOM   1498 C CD2 . PHE B 2  7   ? 17.48489  -8.06267  52.94495  1.000 30.91950 ? 7   PHE B CD2 1 
ATOM   1499 C CE1 . PHE B 2  7   ? 19.81448  -7.10575  54.07874  1.000 33.29198 ? 7   PHE B CE1 1 
ATOM   1500 C CE2 . PHE B 2  7   ? 18.05811  -8.72807  54.01613  1.000 34.28175 ? 7   PHE B CE2 1 
ATOM   1501 C CZ  . PHE B 2  7   ? 19.22469  -8.24852  54.58318  1.000 31.22818 ? 7   PHE B CZ  1 
ATOM   1502 N N   . VAL B 2  8   ? 16.50450  -6.45050  47.97998  1.000 23.88812 ? 8   VAL B N   1 
ATOM   1503 C CA  . VAL B 2  8   ? 16.01699  -5.87698  46.73084  1.000 26.74436 ? 8   VAL B CA  1 
ATOM   1504 C C   . VAL B 2  8   ? 14.49448  -5.85370  46.73488  1.000 25.74852 ? 8   VAL B C   1 
ATOM   1505 O O   . VAL B 2  8   ? 13.84740  -6.82345  47.14583  1.000 25.66289 ? 8   VAL B O   1 
ATOM   1506 C CB  . VAL B 2  8   ? 16.54822  -6.66640  45.51521  1.000 26.78239 ? 8   VAL B CB  1 
ATOM   1507 C CG1 . VAL B 2  8   ? 16.03582  -6.06977  44.21694  1.000 28.03579 ? 8   VAL B CG1 1 
ATOM   1508 C CG2 . VAL B 2  8   ? 18.06996  -6.69553  45.52748  1.000 26.03091 ? 8   VAL B CG2 1 
ATOM   1509 N N   . TYR B 2  9   ? 13.92610  -4.74183  46.26828  1.000 24.71213 ? 9   TYR B N   1 
ATOM   1510 C CA  . TYR B 2  9   ? 12.48730  -4.59858  46.09017  1.000 25.60455 ? 9   TYR B CA  1 
ATOM   1511 C C   . TYR B 2  9   ? 12.21120  -4.11068  44.67633  1.000 26.73610 ? 9   TYR B C   1 
ATOM   1512 O O   . TYR B 2  9   ? 12.84862  -3.16187  44.20785  1.000 23.89923 ? 9   TYR B O   1 
ATOM   1513 C CB  . TYR B 2  9   ? 11.89180  -3.62507  47.11258  1.000 27.91531 ? 9   TYR B CB  1 
ATOM   1514 C CG  . TYR B 2  9   ? 10.37821  -3.59665  47.13915  1.000 26.15612 ? 9   TYR B CG  1 
ATOM   1515 C CD1 . TYR B 2  9   ? 9.66221   -2.80188  46.25436  1.000 27.38579 ? 9   TYR B CD1 1 
ATOM   1516 C CD2 . TYR B 2  9   ? 9.66547   -4.35490  48.05828  1.000 34.51883 ? 9   TYR B CD2 1 
ATOM   1517 C CE1 . TYR B 2  9   ? 8.27882   -2.76819  46.27782  1.000 26.28463 ? 9   TYR B CE1 1 
ATOM   1518 C CE2 . TYR B 2  9   ? 8.28178   -4.32709  48.08934  1.000 25.72078 ? 9   TYR B CE2 1 
ATOM   1519 C CZ  . TYR B 2  9   ? 7.59494   -3.53201  47.19985  1.000 29.37334 ? 9   TYR B CZ  1 
ATOM   1520 O OH  . TYR B 2  9   ? 6.21952   -3.50426  47.23093  1.000 29.96338 ? 9   TYR B OH  1 
ATOM   1521 N N   . GLN B 2  10  ? 11.26077  -4.75568  44.00355  1.000 24.28791 ? 10  GLN B N   1 
ATOM   1522 C CA  . GLN B 2  10  ? 10.86521  -4.38467  42.65364  1.000 27.93840 ? 10  GLN B CA  1 
ATOM   1523 C C   . GLN B 2  10  ? 9.36150   -4.16569  42.59794  1.000 25.05591 ? 10  GLN B C   1 
ATOM   1524 O O   . GLN B 2  10  ? 8.59544   -4.89128  43.23923  1.000 25.47853 ? 10  GLN B O   1 
ATOM   1525 C CB  . GLN B 2  10  ? 11.25447  -5.46102  41.63081  1.000 21.96756 ? 10  GLN B CB  1 
ATOM   1526 C CG  . GLN B 2  10  ? 12.69082  -5.93493  41.71200  1.000 20.01434 ? 10  GLN B CG  1 
ATOM   1527 C CD  . GLN B 2  10  ? 12.99242  -7.02043  40.69698  1.000 27.50955 ? 10  GLN B CD  1 
ATOM   1528 O OE1 . GLN B 2  10  ? 12.63465  -6.90517  39.52284  1.000 23.82597 ? 10  GLN B OE1 1 
ATOM   1529 N NE2 . GLN B 2  10  ? 13.65233  -8.08302  41.14368  1.000 22.14264 ? 10  GLN B NE2 1 
ATOM   1530 N N   . PHE B 2  11  ? 8.94576   -3.16487  41.82380  1.000 23.56867 ? 11  PHE B N   1 
ATOM   1531 C CA  . PHE B 2  11  ? 7.54264   -2.94935  41.49868  1.000 23.29682 ? 11  PHE B CA  1 
ATOM   1532 C C   . PHE B 2  11  ? 7.41074   -2.78605  39.99316  1.000 25.64075 ? 11  PHE B C   1 
ATOM   1533 O O   . PHE B 2  11  ? 8.06824   -1.92554  39.39929  1.000 27.78138 ? 11  PHE B O   1 
ATOM   1534 C CB  . PHE B 2  11  ? 6.96847   -1.72107  42.20883  1.000 24.51742 ? 11  PHE B CB  1 
ATOM   1535 C CG  . PHE B 2  11  ? 5.55683   -1.40013  41.80237  1.000 27.79144 ? 11  PHE B CG  1 
ATOM   1536 C CD1 . PHE B 2  11  ? 4.49984   -2.17063  42.26166  1.000 26.59001 ? 11  PHE B CD1 1 
ATOM   1537 C CD2 . PHE B 2  11  ? 5.28695   -0.34142  40.94954  1.000 25.67843 ? 11  PHE B CD2 1 
ATOM   1538 C CE1 . PHE B 2  11  ? 3.19896   -1.88604  41.88619  1.000 24.49452 ? 11  PHE B CE1 1 
ATOM   1539 C CE2 . PHE B 2  11  ? 3.98670   -0.05178  40.56923  1.000 31.23131 ? 11  PHE B CE2 1 
ATOM   1540 C CZ  . PHE B 2  11  ? 2.94207   -0.82531  41.03916  1.000 28.04566 ? 11  PHE B CZ  1 
ATOM   1541 N N   . LYS B 2  12  ? 6.55896   -3.60409  39.38166  1.000 22.94071 ? 12  LYS B N   1 
ATOM   1542 C CA  . LYS B 2  12  ? 6.37447   -3.61346  37.93618  1.000 24.82832 ? 12  LYS B CA  1 
ATOM   1543 C C   . LYS B 2  12  ? 4.91123   -3.34523  37.61769  1.000 25.18649 ? 12  LYS B C   1 
ATOM   1544 O O   . LYS B 2  12  ? 4.03820   -4.13166  37.99697  1.000 23.38192 ? 12  LYS B O   1 
ATOM   1545 C CB  . LYS B 2  12  ? 6.81353   -4.95130  37.33678  1.000 22.22043 ? 12  LYS B CB  1 
ATOM   1546 C CG  . LYS B 2  12  ? 8.24623   -5.34436  37.65940  1.000 23.53687 ? 12  LYS B CG  1 
ATOM   1547 C CD  . LYS B 2  12  ? 8.53399   -6.77143  37.21508  1.000 23.12068 ? 12  LYS B CD  1 
ATOM   1548 C CE  . LYS B 2  12  ? 10.00727  -7.11274  37.36586  1.000 20.57332 ? 12  LYS B CE  1 
ATOM   1549 N NZ  . LYS B 2  12  ? 10.33404  -8.44260  36.77832  1.000 24.24280 ? 12  LYS B NZ  1 
ATOM   1550 N N   . GLY B 2  13  ? 4.64621   -2.23784  36.92897  1.000 20.80768 ? 13  GLY B N   1 
ATOM   1551 C CA  . GLY B 2  13  ? 3.31746   -1.97031  36.41318  1.000 22.64618 ? 13  GLY B CA  1 
ATOM   1552 C C   . GLY B 2  13  ? 3.20443   -2.44188  34.97883  1.000 26.94526 ? 13  GLY B C   1 
ATOM   1553 O O   . GLY B 2  13  ? 3.55888   -1.71088  34.04895  1.000 27.65587 ? 13  GLY B O   1 
ATOM   1554 N N   . MET B 2  14  ? 2.71548   -3.66252  34.78472  1.000 25.70811 ? 14  MET B N   1 
ATOM   1555 C CA  . MET B 2  14  ? 2.81028   -4.34220  33.50149  1.000 20.68065 ? 14  MET B CA  1 
ATOM   1556 C C   . MET B 2  14  ? 1.47406   -4.33437  32.76999  1.000 26.92768 ? 14  MET B C   1 
ATOM   1557 O O   . MET B 2  14  ? 0.41965   -4.56907  33.36870  1.000 22.38926 ? 14  MET B O   1 
ATOM   1558 C CB  . MET B 2  14  ? 3.30210   -5.77720  33.69754  1.000 21.35814 ? 14  MET B CB  1 
ATOM   1559 C CG  . MET B 2  14  ? 4.69514   -5.84808  34.30947  1.000 22.91513 ? 14  MET B CG  1 
ATOM   1560 S SD  . MET B 2  14  ? 5.40904   -7.50020  34.30289  1.000 25.21543 ? 14  MET B SD  1 
ATOM   1561 C CE  . MET B 2  14  ? 5.90549   -7.64154  32.58754  1.000 20.40605 ? 14  MET B CE  1 
ATOM   1562 N N   . CYS B 2  15  ? 1.53250   -4.06221  31.46732  1.000 27.64165 ? 15  CYS B N   1 
ATOM   1563 C CA  . CYS B 2  15  ? 0.36455   -4.01708  30.60033  1.000 23.72290 ? 15  CYS B CA  1 
ATOM   1564 C C   . CYS B 2  15  ? 0.50007   -5.06601  29.50638  1.000 28.19255 ? 15  CYS B C   1 
ATOM   1565 O O   . CYS B 2  15  ? 1.56786   -5.21163  28.90235  1.000 27.66843 ? 15  CYS B O   1 
ATOM   1566 C CB  . CYS B 2  15  ? 0.19788   -2.63247  29.96827  1.000 25.76110 ? 15  CYS B CB  1 
ATOM   1567 S SG  . CYS B 2  15  ? -0.07327  -1.29744  31.14667  1.000 33.72629 ? 15  CYS B SG  1 
ATOM   1568 N N   . TYR B 2  16  ? -0.58577  -5.79082  29.24926  1.000 22.59940 ? 16  TYR B N   1 
ATOM   1569 C CA  . TYR B 2  16  ? -0.61649  -6.82830  28.22749  1.000 21.04752 ? 16  TYR B CA  1 
ATOM   1570 C C   . TYR B 2  16  ? -1.68357  -6.48491  27.19878  1.000 30.07129 ? 16  TYR B C   1 
ATOM   1571 O O   . TYR B 2  16  ? -2.84603  -6.26172  27.55383  1.000 30.20382 ? 16  TYR B O   1 
ATOM   1572 C CB  . TYR B 2  16  ? -0.88407  -8.20537  28.84435  1.000 20.80622 ? 16  TYR B CB  1 
ATOM   1573 C CG  . TYR B 2  16  ? 0.15385   -8.62807  29.86295  1.000 25.83263 ? 16  TYR B CG  1 
ATOM   1574 C CD1 . TYR B 2  16  ? 0.04788   -8.24166  31.19449  1.000 23.69721 ? 16  TYR B CD1 1 
ATOM   1575 C CD2 . TYR B 2  16  ? 1.24383   -9.40798  29.49225  1.000 28.50082 ? 16  TYR B CD2 1 
ATOM   1576 C CE1 . TYR B 2  16  ? 0.99578   -8.62119  32.12811  1.000 20.85596 ? 16  TYR B CE1 1 
ATOM   1577 C CE2 . TYR B 2  16  ? 2.19893   -9.79388  30.42239  1.000 23.61832 ? 16  TYR B CE2 1 
ATOM   1578 C CZ  . TYR B 2  16  ? 2.06790   -9.39623  31.73753  1.000 24.21421 ? 16  TYR B CZ  1 
ATOM   1579 O OH  . TYR B 2  16  ? 3.01097   -9.77500  32.66680  1.000 26.87843 ? 16  TYR B OH  1 
ATOM   1580 N N   . PHE B 2  17  ? -1.28700  -6.44366  25.92936  1.000 24.24336 ? 17  PHE B N   1 
ATOM   1581 C CA  . PHE B 2  17  ? -2.17280  -6.07019  24.83550  1.000 25.67943 ? 17  PHE B CA  1 
ATOM   1582 C C   . PHE B 2  17  ? -2.29927  -7.23441  23.86469  1.000 28.96579 ? 17  PHE B C   1 
ATOM   1583 O O   . PHE B 2  17  ? -1.29429  -7.84909  23.49103  1.000 26.94241 ? 17  PHE B O   1 
ATOM   1584 C CB  . PHE B 2  17  ? -1.65254  -4.83057  24.09953  1.000 26.39671 ? 17  PHE B CB  1 
ATOM   1585 C CG  . PHE B 2  17  ? -1.36378  -3.66064  24.99984  1.000 22.04075 ? 17  PHE B CG  1 
ATOM   1586 C CD1 . PHE B 2  17  ? -2.34952  -2.73222  25.29031  1.000 20.68442 ? 17  PHE B CD1 1 
ATOM   1587 C CD2 . PHE B 2  17  ? -0.10268  -3.48627  25.54872  1.000 23.36664 ? 17  PHE B CD2 1 
ATOM   1588 C CE1 . PHE B 2  17  ? -2.08539  -1.65295  26.11510  1.000 24.85326 ? 17  PHE B CE1 1 
ATOM   1589 C CE2 . PHE B 2  17  ? 0.16871   -2.41018  26.37451  1.000 25.10796 ? 17  PHE B CE2 1 
ATOM   1590 C CZ  . PHE B 2  17  ? -0.82442  -1.49256  26.65891  1.000 29.93293 ? 17  PHE B CZ  1 
ATOM   1591 N N   . THR B 2  18  ? -3.53173  -7.53097  23.45860  1.000 28.02603 ? 18  THR B N   1 
ATOM   1592 C CA  . THR B 2  18  ? -3.80984  -8.54397  22.44970  1.000 33.21826 ? 18  THR B CA  1 
ATOM   1593 C C   . THR B 2  18  ? -4.77646  -7.95970  21.43134  1.000 32.65901 ? 18  THR B C   1 
ATOM   1594 O O   . THR B 2  18  ? -5.82857  -7.43130  21.80610  1.000 31.22014 ? 18  THR B O   1 
ATOM   1595 C CB  . THR B 2  18  ? -4.39657  -9.81491  23.07334  1.000 34.34429 ? 18  THR B CB  1 
ATOM   1596 O OG1 . THR B 2  18  ? -3.52370  -10.28966 24.10608  1.000 36.08967 ? 18  THR B OG1 1 
ATOM   1597 C CG2 . THR B 2  18  ? -4.55790  -10.89807 22.01733  1.000 40.62628 ? 18  THR B CG2 1 
ATOM   1598 N N   . ASN B 2  19  ? -4.41408  -8.05222  20.14928  1.000 31.62758 ? 19  ASN B N   1 
ATOM   1599 C CA  . ASN B 2  19  ? -5.19970  -7.46987  19.05890  1.000 36.82756 ? 19  ASN B CA  1 
ATOM   1600 C C   . ASN B 2  19  ? -5.37975  -5.96663  19.26068  1.000 35.63890 ? 19  ASN B C   1 
ATOM   1601 O O   . ASN B 2  19  ? -6.49584  -5.44245  19.25416  1.000 37.55499 ? 19  ASN B O   1 
ATOM   1602 C CB  . ASN B 2  19  ? -6.55518  -8.16607  18.91839  1.000 35.25984 ? 19  ASN B CB  1 
ATOM   1603 C CG  . ASN B 2  19  ? -6.43368  -9.57532  18.38857  1.000 44.01180 ? 19  ASN B CG  1 
ATOM   1604 O OD1 . ASN B 2  19  ? -5.36970  -9.99214  17.93105  1.000 44.55100 ? 19  ASN B OD1 1 
ATOM   1605 N ND2 . ASN B 2  19  ? -7.52916  -10.32001 18.44587  1.000 57.54901 ? 19  ASN B ND2 1 
ATOM   1606 N N   . GLY B 2  20  ? -4.26195  -5.27041  19.44307  1.000 31.51360 ? 20  GLY B N   1 
ATOM   1607 C CA  . GLY B 2  20  ? -4.30718  -3.85846  19.76284  1.000 33.66869 ? 20  GLY B CA  1 
ATOM   1608 C C   . GLY B 2  20  ? -4.91089  -3.60169  21.12764  1.000 35.98360 ? 20  GLY B C   1 
ATOM   1609 O O   . GLY B 2  20  ? -4.36896  -4.04457  22.14509  1.000 33.65955 ? 20  GLY B O   1 
ATOM   1610 N N   . THR B 2  21  ? -6.04005  -2.89346  21.16442  1.000 34.94289 ? 21  THR B N   1 
ATOM   1611 C CA  . THR B 2  21  ? -6.72952  -2.59008  22.41028  1.000 31.45443 ? 21  THR B CA  1 
ATOM   1612 C C   . THR B 2  21  ? -7.97670  -3.44303  22.60531  1.000 32.97639 ? 21  THR B C   1 
ATOM   1613 O O   . THR B 2  21  ? -8.86208  -3.06584  23.38033  1.000 33.76063 ? 21  THR B O   1 
ATOM   1614 C CB  . THR B 2  21  ? -7.09770  -1.10679  22.47304  1.000 33.93506 ? 21  THR B CB  1 
ATOM   1615 O OG1 . THR B 2  21  ? -7.72362  -0.70991  21.24643  1.000 26.59459 ? 21  THR B OG1 1 
ATOM   1616 C CG2 . THR B 2  21  ? -5.84987  -0.26447  22.69703  1.000 38.62574 ? 21  THR B CG2 1 
ATOM   1617 N N   . GLU B 2  22  ? -8.06610  -4.58277  21.91625  1.000 36.91776 ? 22  GLU B N   1 
ATOM   1618 C CA  . GLU B 2  22  ? -9.22432  -5.45458  22.08050  1.000 33.05050 ? 22  GLU B CA  1 
ATOM   1619 C C   . GLU B 2  22  ? -9.23897  -6.08318  23.46862  1.000 34.82071 ? 22  GLU B C   1 
ATOM   1620 O O   . GLU B 2  22  ? -10.26861 -6.07561  24.15266  1.000 35.66358 ? 22  GLU B O   1 
ATOM   1621 C CB  . GLU B 2  22  ? -9.23335  -6.52847  20.99271  1.000 35.30787 ? 22  GLU B CB  1 
ATOM   1622 C CG  . GLU B 2  22  ? -10.22147 -7.65398  21.24466  1.000 41.57437 ? 22  GLU B CG  1 
ATOM   1623 C CD  . GLU B 2  22  ? -10.21653 -8.69200  20.14069  1.000 56.39954 ? 22  GLU B CD  1 
ATOM   1624 O OE1 . GLU B 2  22  ? -10.33066 -9.89530  20.45500  1.000 67.95136 ? 22  GLU B OE1 1 
ATOM   1625 O OE2 . GLU B 2  22  ? -10.10301 -8.30518  18.95806  1.000 62.19167 ? 22  GLU B OE2 1 
ATOM   1626 N N   . ARG B 2  23  ? -8.10529  -6.63149  23.90283  1.000 30.21954 ? 23  ARG B N   1 
ATOM   1627 C CA  . ARG B 2  23  ? -7.93011  -7.09754  25.27345  1.000 38.77167 ? 23  ARG B CA  1 
ATOM   1628 C C   . ARG B 2  23  ? -6.74938  -6.36743  25.89428  1.000 32.84905 ? 23  ARG B C   1 
ATOM   1629 O O   . ARG B 2  23  ? -5.61210  -6.51460  25.43486  1.000 33.27804 ? 23  ARG B O   1 
ATOM   1630 C CB  . ARG B 2  23  ? -7.71379  -8.61110  25.34246  1.000 37.05274 ? 23  ARG B CB  1 
ATOM   1631 C CG  . ARG B 2  23  ? -7.50871  -9.10285  26.77499  1.000 41.87441 ? 23  ARG B CG  1 
ATOM   1632 C CD  . ARG B 2  23  ? -8.18883  -10.43826 27.03767  1.000 46.23083 ? 23  ARG B CD  1 
ATOM   1633 N NE  . ARG B 2  23  ? -7.44591  -11.26483 27.98342  1.000 49.16291 ? 23  ARG B NE  1 
ATOM   1634 C CZ  . ARG B 2  23  ? -7.40140  -11.05660 29.29344  1.000 45.55323 ? 23  ARG B CZ  1 
ATOM   1635 N NH1 . ARG B 2  23  ? -8.03900  -10.04184 29.85633  1.000 31.40888 ? 23  ARG B NH1 1 
ATOM   1636 N NH2 . ARG B 2  23  ? -6.70207  -11.88979 30.05932  1.000 46.03977 ? 23  ARG B NH2 1 
ATOM   1637 N N   . VAL B 2  24  ? -7.02261  -5.58540  26.93398  1.000 31.60677 ? 24  VAL B N   1 
ATOM   1638 C CA  . VAL B 2  24  ? -6.00402  -4.85904  27.68019  1.000 29.36475 ? 24  VAL B CA  1 
ATOM   1639 C C   . VAL B 2  24  ? -6.05508  -5.33380  29.12540  1.000 30.16600 ? 24  VAL B C   1 
ATOM   1640 O O   . VAL B 2  24  ? -7.12959  -5.35916  29.73715  1.000 29.00054 ? 24  VAL B O   1 
ATOM   1641 C CB  . VAL B 2  24  ? -6.21299  -3.33668  27.59114  1.000 28.34573 ? 24  VAL B CB  1 
ATOM   1642 C CG1 . VAL B 2  24  ? -5.06793  -2.61048  28.25977  1.000 25.24901 ? 24  VAL B CG1 1 
ATOM   1643 C CG2 . VAL B 2  24  ? -6.34852  -2.90371  26.13686  1.000 29.54228 ? 24  VAL B CG2 1 
ATOM   1644 N N   . ARG B 2  25  ? -4.89723  -5.70633  29.66771  1.000 25.94195 ? 25  ARG B N   1 
ATOM   1645 C CA  . ARG B 2  25  ? -4.81796  -6.31128  30.99060  1.000 26.45985 ? 25  ARG B CA  1 
ATOM   1646 C C   . ARG B 2  25  ? -3.63738  -5.72948  31.75024  1.000 27.82132 ? 25  ARG B C   1 
ATOM   1647 O O   . ARG B 2  25  ? -2.51910  -5.69315  31.22896  1.000 26.73535 ? 25  ARG B O   1 
ATOM   1648 C CB  . ARG B 2  25  ? -4.67650  -7.83236  30.87887  1.000 26.97936 ? 25  ARG B CB  1 
ATOM   1649 C CG  . ARG B 2  25  ? -4.49860  -8.56344  32.19745  1.000 24.25168 ? 25  ARG B CG  1 
ATOM   1650 C CD  . ARG B 2  25  ? -4.44831  -10.05842 31.93894  1.000 24.95471 ? 25  ARG B CD  1 
ATOM   1651 N NE  . ARG B 2  25  ? -4.18336  -10.83834 33.14058  1.000 26.77866 ? 25  ARG B NE  1 
ATOM   1652 C CZ  . ARG B 2  25  ? -3.81729  -12.11236 33.13039  1.000 30.60000 ? 25  ARG B CZ  1 
ATOM   1653 N NH1 . ARG B 2  25  ? -3.64897  -12.77309 31.99626  1.000 24.08590 ? 25  ARG B NH1 1 
ATOM   1654 N NH2 . ARG B 2  25  ? -3.61993  -12.74029 34.28558  1.000 25.02417 ? 25  ARG B NH2 1 
ATOM   1655 N N   . LEU B 2  26  ? -3.88458  -5.28478  32.97850  1.000 27.04793 ? 26  LEU B N   1 
ATOM   1656 C CA  . LEU B 2  26  ? -2.84696  -4.73897  33.84183  1.000 24.71747 ? 26  LEU B CA  1 
ATOM   1657 C C   . LEU B 2  26  ? -2.54297  -5.72491  34.96009  1.000 27.99725 ? 26  LEU B C   1 
ATOM   1658 O O   . LEU B 2  26  ? -3.46023  -6.22626  35.61948  1.000 25.36973 ? 26  LEU B O   1 
ATOM   1659 C CB  . LEU B 2  26  ? -3.26679  -3.39062  34.43242  1.000 23.95446 ? 26  LEU B CB  1 
ATOM   1660 C CG  . LEU B 2  26  ? -2.27119  -2.78257  35.42711  1.000 30.08657 ? 26  LEU B CG  1 
ATOM   1661 C CD1 . LEU B 2  26  ? -1.84118  -1.39012  34.99633  1.000 38.80420 ? 26  LEU B CD1 1 
ATOM   1662 C CD2 . LEU B 2  26  ? -2.85821  -2.74839  36.82735  1.000 30.58870 ? 26  LEU B CD2 1 
ATOM   1663 N N   . VAL B 2  27  ? -1.25831  -6.00535  35.16462  1.000 25.36533 ? 27  VAL B N   1 
ATOM   1664 C CA  . VAL B 2  27  ? -0.78950  -6.83474  36.27091  1.000 25.97169 ? 27  VAL B CA  1 
ATOM   1665 C C   . VAL B 2  27  ? 0.35284   -6.07575  36.93337  1.000 25.16064 ? 27  VAL B C   1 
ATOM   1666 O O   . VAL B 2  27  ? 1.46297   -6.01898  36.39344  1.000 26.44576 ? 27  VAL B O   1 
ATOM   1667 C CB  . VAL B 2  27  ? -0.33695  -8.22802  35.81793  1.000 23.84047 ? 27  VAL B CB  1 
ATOM   1668 C CG1 . VAL B 2  27  ? 0.03768   -9.07828  37.02493  1.000 24.52288 ? 27  VAL B CG1 1 
ATOM   1669 C CG2 . VAL B 2  27  ? -1.42486  -8.91160  35.00215  1.000 21.85184 ? 27  VAL B CG2 1 
ATOM   1670 N N   . SER B 2  28  ? 0.08626   -5.48141  38.09372  1.000 23.59444 ? 28  SER B N   1 
ATOM   1671 C CA  . SER B 2  28  ? 1.12544   -4.83813  38.88541  1.000 24.73993 ? 28  SER B CA  1 
ATOM   1672 C C   . SER B 2  28  ? 1.67162   -5.83749  39.89758  1.000 27.77208 ? 28  SER B C   1 
ATOM   1673 O O   . SER B 2  28  ? 0.90249   -6.49836  40.60298  1.000 27.96468 ? 28  SER B O   1 
ATOM   1674 C CB  . SER B 2  28  ? 0.58806   -3.59366  39.59390  1.000 27.11991 ? 28  SER B CB  1 
ATOM   1675 O OG  . SER B 2  28  ? -0.48164  -3.91772  40.46201  1.000 30.20736 ? 28  SER B OG  1 
ATOM   1676 N N   . ARG B 2  29  ? 2.99720   -5.94942  39.96231  1.000 22.81554 ? 29  ARG B N   1 
ATOM   1677 C CA  . ARG B 2  29  ? 3.66503   -6.97522  40.75494  1.000 25.68862 ? 29  ARG B CA  1 
ATOM   1678 C C   . ARG B 2  29  ? 4.59929   -6.31967  41.76217  1.000 27.68887 ? 29  ARG B C   1 
ATOM   1679 O O   . ARG B 2  29  ? 5.49152   -5.55430  41.38014  1.000 25.60238 ? 29  ARG B O   1 
ATOM   1680 C CB  . ARG B 2  29  ? 4.44580   -7.93660  39.85480  1.000 25.69441 ? 29  ARG B CB  1 
ATOM   1681 C CG  . ARG B 2  29  ? 3.67769   -8.41888  38.63339  1.000 21.99335 ? 29  ARG B CG  1 
ATOM   1682 C CD  . ARG B 2  29  ? 4.54756   -9.30459  37.75478  1.000 23.51172 ? 29  ARG B CD  1 
ATOM   1683 N NE  . ARG B 2  29  ? 3.87651   -9.68688  36.51732  1.000 26.48444 ? 29  ARG B NE  1 
ATOM   1684 C CZ  . ARG B 2  29  ? 3.11861   -10.76636 36.38026  1.000 27.14823 ? 29  ARG B CZ  1 
ATOM   1685 N NH1 . ARG B 2  29  ? 2.90008   -11.59077 37.39224  1.000 23.08922 ? 29  ARG B NH1 1 
ATOM   1686 N NH2 . ARG B 2  29  ? 2.56572   -11.02554 35.19866  1.000 24.71423 ? 29  ARG B NH2 1 
ATOM   1687 N N   . SER B 2  30  ? 4.39730   -6.62741  43.04119  1.000 25.75760 ? 30  SER B N   1 
ATOM   1688 C CA  . SER B 2  30  ? 5.29944   -6.21875  44.11086  1.000 22.06449 ? 30  SER B CA  1 
ATOM   1689 C C   . SER B 2  30  ? 6.18570   -7.40641  44.46655  1.000 22.45072 ? 30  SER B C   1 
ATOM   1690 O O   . SER B 2  30  ? 5.68068   -8.47701  44.82214  1.000 22.12448 ? 30  SER B O   1 
ATOM   1691 C CB  . SER B 2  30  ? 4.51891   -5.73668  45.33316  1.000 26.53075 ? 30  SER B CB  1 
ATOM   1692 O OG  . SER B 2  30  ? 3.68860   -4.63587  45.00594  1.000 25.47856 ? 30  SER B OG  1 
ATOM   1693 N N   . ILE B 2  31  ? 7.49984   -7.21935  44.36827  1.000 20.82169 ? 31  ILE B N   1 
ATOM   1694 C CA  . ILE B 2  31  ? 8.45682   -8.31585  44.44919  1.000 22.72258 ? 31  ILE B CA  1 
ATOM   1695 C C   . ILE B 2  31  ? 9.48568   -8.00356  45.52683  1.000 25.37541 ? 31  ILE B C   1 
ATOM   1696 O O   . ILE B 2  31  ? 10.09203  -6.92638  45.52139  1.000 20.85968 ? 31  ILE B O   1 
ATOM   1697 C CB  . ILE B 2  31  ? 9.15101   -8.55988  43.09419  1.000 25.29881 ? 31  ILE B CB  1 
ATOM   1698 C CG1 . ILE B 2  31  ? 8.11441   -8.86171  42.00786  1.000 23.01902 ? 31  ILE B CG1 1 
ATOM   1699 C CG2 . ILE B 2  31  ? 10.16380  -9.69330  43.19800  1.000 22.05003 ? 31  ILE B CG2 1 
ATOM   1700 C CD1 . ILE B 2  31  ? 8.34692   -8.10709  40.72040  1.000 24.52099 ? 31  ILE B CD1 1 
ATOM   1701 N N   . TYR B 2  32  ? 9.67693   -8.94311  46.44879  1.000 26.96370 ? 32  TYR B N   1 
ATOM   1702 C CA  . TYR B 2  32  ? 10.74813  -8.88015  47.43406  1.000 23.08838 ? 32  TYR B CA  1 
ATOM   1703 C C   . TYR B 2  32  ? 11.86625  -9.80304  46.96879  1.000 23.56763 ? 32  TYR B C   1 
ATOM   1704 O O   . TYR B 2  32  ? 11.64931  -11.00965 46.80874  1.000 25.31911 ? 32  TYR B O   1 
ATOM   1705 C CB  . TYR B 2  32  ? 10.24957  -9.28444  48.82097  1.000 26.36145 ? 32  TYR B CB  1 
ATOM   1706 C CG  . TYR B 2  32  ? 11.32458  -9.26161  49.88555  1.000 23.86182 ? 32  TYR B CG  1 
ATOM   1707 C CD1 . TYR B 2  32  ? 11.86085  -8.06134  50.33272  1.000 27.12471 ? 32  TYR B CD1 1 
ATOM   1708 C CD2 . TYR B 2  32  ? 11.80424  -10.44021 50.44080  1.000 27.58431 ? 32  TYR B CD2 1 
ATOM   1709 C CE1 . TYR B 2  32  ? 12.84443  -8.03497  51.30619  1.000 33.29295 ? 32  TYR B CE1 1 
ATOM   1710 C CE2 . TYR B 2  32  ? 12.78788  -10.42446 51.41540  1.000 31.16417 ? 32  TYR B CE2 1 
ATOM   1711 C CZ  . TYR B 2  32  ? 13.30299  -9.21911  51.84423  1.000 32.48155 ? 32  TYR B CZ  1 
ATOM   1712 O OH  . TYR B 2  32  ? 14.28210  -9.19870  52.81130  1.000 32.50634 ? 32  TYR B OH  1 
ATOM   1713 N N   . ASN B 2  33  ? 13.05438  -9.23369  46.75326  1.000 24.51711 ? 33  ASN B N   1 
ATOM   1714 C CA  . ASN B 2  33  ? 14.14477  -9.93089  46.07862  1.000 25.49687 ? 33  ASN B CA  1 
ATOM   1715 C C   . ASN B 2  33  ? 13.66487  -10.44879 44.72628  1.000 24.97722 ? 33  ASN B C   1 
ATOM   1716 O O   . ASN B 2  33  ? 13.38125  -9.65451  43.82431  1.000 22.79929 ? 33  ASN B O   1 
ATOM   1717 C CB  . ASN B 2  33  ? 14.69631  -11.06475 46.94929  1.000 23.80376 ? 33  ASN B CB  1 
ATOM   1718 C CG  . ASN B 2  33  ? 15.45147  -10.55040 48.16421  1.000 32.76025 ? 33  ASN B CG  1 
ATOM   1719 O OD1 . ASN B 2  33  ? 16.11657  -9.51513  48.10141  1.000 31.73135 ? 33  ASN B OD1 1 
ATOM   1720 N ND2 . ASN B 2  33  ? 15.35302  -11.27247 49.27671  1.000 28.22343 ? 33  ASN B ND2 1 
ATOM   1721 N N   . ARG B 2  34  ? 13.56315  -11.76851 44.57077  1.000 24.19288 ? 34  ARG B N   1 
ATOM   1722 C CA  . ARG B 2  34  ? 13.04360  -12.36716 43.34662  1.000 24.97391 ? 34  ARG B CA  1 
ATOM   1723 C C   . ARG B 2  34  ? 11.70362  -13.06075 43.55484  1.000 30.36837 ? 34  ARG B C   1 
ATOM   1724 O O   . ARG B 2  34  ? 11.26115  -13.81250 42.67975  1.000 34.52445 ? 34  ARG B O   1 
ATOM   1725 C CB  . ARG B 2  34  ? 14.05532  -13.35421 42.76325  1.000 30.68469 ? 34  ARG B CB  1 
ATOM   1726 C CG  . ARG B 2  34  ? 15.06893  -12.70870 41.83769  1.000 31.46423 ? 34  ARG B CG  1 
ATOM   1727 C CD  . ARG B 2  34  ? 16.04921  -13.72802 41.29459  1.000 29.82875 ? 34  ARG B CD  1 
ATOM   1728 N NE  . ARG B 2  34  ? 15.51823  -14.42077 40.12838  1.000 33.29406 ? 34  ARG B NE  1 
ATOM   1729 C CZ  . ARG B 2  34  ? 15.72544  -15.70232 39.86157  1.000 42.44218 ? 34  ARG B CZ  1 
ATOM   1730 N NH1 . ARG B 2  34  ? 16.43870  -16.46918 40.66966  1.000 39.06435 ? 34  ARG B NH1 1 
ATOM   1731 N NH2 . ARG B 2  34  ? 15.20650  -16.22666 38.75469  1.000 43.70131 ? 34  ARG B NH2 1 
ATOM   1732 N N   . GLU B 2  35  ? 11.04607  -12.82301 44.68314  1.000 22.88665 ? 35  GLU B N   1 
ATOM   1733 C CA  . GLU B 2  35  ? 9.78710   -13.47538 45.02266  1.000 32.47974 ? 35  GLU B CA  1 
ATOM   1734 C C   . GLU B 2  35  ? 8.66229   -12.45624 44.89266  1.000 23.65854 ? 35  GLU B C   1 
ATOM   1735 O O   . GLU B 2  35  ? 8.60588   -11.48625 45.65632  1.000 21.99402 ? 35  GLU B O   1 
ATOM   1736 C CB  . GLU B 2  35  ? 9.84889   -14.05632 46.43526  1.000 31.14378 ? 35  GLU B CB  1 
ATOM   1737 C CG  . GLU B 2  35  ? 8.51563   -14.53073 46.99476  1.000 34.97424 ? 35  GLU B CG  1 
ATOM   1738 C CD  . GLU B 2  35  ? 8.65306   -15.12939 48.38693  1.000 55.68522 ? 35  GLU B CD  1 
ATOM   1739 O OE1 . GLU B 2  35  ? 9.50155   -16.02966 48.56432  1.000 60.23073 ? 35  GLU B OE1 1 
ATOM   1740 O OE2 . GLU B 2  35  ? 7.91769   -14.69981 49.30333  1.000 38.20432 ? 35  GLU B OE2 1 
ATOM   1741 N N   . GLU B 2  36  ? 7.78038   -12.66306 43.91750  1.000 21.18655 ? 36  GLU B N   1 
ATOM   1742 C CA  . GLU B 2  36  ? 6.55630   -11.87632 43.85863  1.000 26.85348 ? 36  GLU B CA  1 
ATOM   1743 C C   . GLU B 2  36  ? 5.68762   -12.21270 45.06298  1.000 21.51278 ? 36  GLU B C   1 
ATOM   1744 O O   . GLU B 2  36  ? 5.39708   -13.38446 45.32051  1.000 24.38042 ? 36  GLU B O   1 
ATOM   1745 C CB  . GLU B 2  36  ? 5.79722   -12.14963 42.56130  1.000 21.28887 ? 36  GLU B CB  1 
ATOM   1746 C CG  . GLU B 2  36  ? 4.62772   -11.20243 42.32368  1.000 23.43054 ? 36  GLU B CG  1 
ATOM   1747 C CD  . GLU B 2  36  ? 3.77080   -11.60513 41.13428  1.000 32.94268 ? 36  GLU B CD  1 
ATOM   1748 O OE1 . GLU B 2  36  ? 4.00574   -12.68992 40.56184  1.000 31.43303 ? 36  GLU B OE1 1 
ATOM   1749 O OE2 . GLU B 2  36  ? 2.86144   -10.83169 40.76891  1.000 36.84454 ? 36  GLU B OE2 1 
ATOM   1750 N N   . ILE B 2  37  ? 5.28379   -11.18716 45.81094  1.000 20.57337 ? 37  ILE B N   1 
ATOM   1751 C CA  . ILE B 2  37  ? 4.52930   -11.39090 47.03576  1.000 22.31510 ? 37  ILE B CA  1 
ATOM   1752 C C   . ILE B 2  37  ? 3.09156   -10.88827 46.93465  1.000 27.13900 ? 37  ILE B C   1 
ATOM   1753 O O   . ILE B 2  37  ? 2.19751   -11.49064 47.54144  1.000 24.13950 ? 37  ILE B O   1 
ATOM   1754 C CB  . ILE B 2  37  ? 5.24982   -10.74449 48.23892  1.000 22.28865 ? 37  ILE B CB  1 
ATOM   1755 C CG1 . ILE B 2  37  ? 5.37417   -9.23135  48.05086  1.000 24.22836 ? 37  ILE B CG1 1 
ATOM   1756 C CG2 . ILE B 2  37  ? 6.62534   -11.36653 48.43143  1.000 23.27878 ? 37  ILE B CG2 1 
ATOM   1757 C CD1 . ILE B 2  37  ? 5.67514   -8.48212  49.33054  1.000 30.58915 ? 37  ILE B CD1 1 
ATOM   1758 N N   . VAL B 2  38  ? 2.84151   -9.80004  46.20402  1.000 22.11292 ? 38  VAL B N   1 
ATOM   1759 C CA  . VAL B 2  38  ? 1.49838   -9.27215  45.99903  1.000 24.48073 ? 38  VAL B CA  1 
ATOM   1760 C C   . VAL B 2  38  ? 1.33112   -8.96144  44.51947  1.000 25.74990 ? 38  VAL B C   1 
ATOM   1761 O O   . VAL B 2  38  ? 2.29964   -8.65952  43.81494  1.000 27.56902 ? 38  VAL B O   1 
ATOM   1762 C CB  . VAL B 2  38  ? 1.21144   -8.00711  46.84526  1.000 30.08646 ? 38  VAL B CB  1 
ATOM   1763 C CG1 . VAL B 2  38  ? -0.29053  -7.74671  46.92803  1.000 26.97960 ? 38  VAL B CG1 1 
ATOM   1764 C CG2 . VAL B 2  38  ? 1.80639   -8.12749  48.23494  1.000 35.41688 ? 38  VAL B CG2 1 
ATOM   1765 N N   . ARG B 2  39  ? 0.08681   -9.02495  44.05258  1.000 25.91342 ? 39  ARG B N   1 
ATOM   1766 C CA  . ARG B 2  39  ? -0.22262  -8.81164  42.64819  1.000 23.80834 ? 39  ARG B CA  1 
ATOM   1767 C C   . ARG B 2  39  ? -1.62395  -8.23334  42.52917  1.000 26.81857 ? 39  ARG B C   1 
ATOM   1768 O O   . ARG B 2  39  ? -2.54278  -8.67663  43.22330  1.000 26.40965 ? 39  ARG B O   1 
ATOM   1769 C CB  . ARG B 2  39  ? -0.11406  -10.12667 41.86524  1.000 26.20972 ? 39  ARG B CB  1 
ATOM   1770 C CG  . ARG B 2  39  ? -0.81198  -10.13550 40.51877  1.000 33.84682 ? 39  ARG B CG  1 
ATOM   1771 C CD  . ARG B 2  39  ? -0.99618  -11.56029 40.01481  1.000 32.06971 ? 39  ARG B CD  1 
ATOM   1772 N NE  . ARG B 2  39  ? 0.27592   -12.26091 39.88242  1.000 34.59264 ? 39  ARG B NE  1 
ATOM   1773 C CZ  . ARG B 2  39  ? 0.42784   -13.43206 39.27890  1.000 33.52989 ? 39  ARG B CZ  1 
ATOM   1774 N NH1 . ARG B 2  39  ? -0.59811  -14.07049 38.73919  1.000 27.34081 ? 39  ARG B NH1 1 
ATOM   1775 N NH2 . ARG B 2  39  ? 1.63905   -13.97777 39.21738  1.000 30.16937 ? 39  ARG B NH2 1 
ATOM   1776 N N   . PHE B 2  40  ? -1.77975  -7.23309  41.66198  1.000 28.99805 ? 40  PHE B N   1 
ATOM   1777 C CA  . PHE B 2  40  ? -3.09584  -6.75449  41.25071  1.000 21.08609 ? 40  PHE B CA  1 
ATOM   1778 C C   . PHE B 2  40  ? -3.27821  -7.07831  39.77467  1.000 23.13613 ? 40  PHE B C   1 
ATOM   1779 O O   . PHE B 2  40  ? -2.67289  -6.43408  38.91114  1.000 24.72806 ? 40  PHE B O   1 
ATOM   1780 C CB  . PHE B 2  40  ? -3.27957  -5.25844  41.49475  1.000 17.39475 ? 40  PHE B CB  1 
ATOM   1781 C CG  . PHE B 2  40  ? -4.64440  -4.75762  41.09584  1.000 29.66090 ? 40  PHE B CG  1 
ATOM   1782 C CD1 . PHE B 2  40  ? -5.70686  -4.82207  41.98510  1.000 24.48158 ? 40  PHE B CD1 1 
ATOM   1783 C CD2 . PHE B 2  40  ? -4.87361  -4.25593  39.82159  1.000 26.12377 ? 40  PHE B CD2 1 
ATOM   1784 C CE1 . PHE B 2  40  ? -6.96649  -4.37951  41.61851  1.000 27.59548 ? 40  PHE B CE1 1 
ATOM   1785 C CE2 . PHE B 2  40  ? -6.13052  -3.81339  39.44826  1.000 25.16727 ? 40  PHE B CE2 1 
ATOM   1786 C CZ  . PHE B 2  40  ? -7.17828  -3.87479  40.34752  1.000 32.07729 ? 40  PHE B CZ  1 
ATOM   1787 N N   . ASP B 2  41  ? -4.11517  -8.06903  39.49290  1.000 23.15645 ? 41  ASP B N   1 
ATOM   1788 C CA  . ASP B 2  41  ? -4.47684  -8.44371  38.13395  1.000 21.52232 ? 41  ASP B CA  1 
ATOM   1789 C C   . ASP B 2  41  ? -5.83252  -7.82211  37.81735  1.000 24.66904 ? 41  ASP B C   1 
ATOM   1790 O O   . ASP B 2  41  ? -6.80613  -8.04739  38.54472  1.000 26.33913 ? 41  ASP B O   1 
ATOM   1791 C CB  . ASP B 2  41  ? -4.51711  -9.96635  37.99562  1.000 22.02689 ? 41  ASP B CB  1 
ATOM   1792 C CG  . ASP B 2  41  ? -4.76301  -10.42850 36.57086  1.000 26.30675 ? 41  ASP B CG  1 
ATOM   1793 O OD1 . ASP B 2  41  ? -4.98692  -9.58107  35.67982  1.000 26.27359 ? 41  ASP B OD1 1 
ATOM   1794 O OD2 . ASP B 2  41  ? -4.72908  -11.65685 36.34468  1.000 25.84758 ? 41  ASP B OD2 1 
ATOM   1795 N N   . SER B 2  42  ? -5.89135  -7.03559  36.73816  1.000 24.00530 ? 42  SER B N   1 
ATOM   1796 C CA  . SER B 2  42  ? -7.13543  -6.35621  36.38968  1.000 23.45408 ? 42  SER B CA  1 
ATOM   1797 C C   . SER B 2  42  ? -8.24401  -7.34708  36.06052  1.000 23.30250 ? 42  SER B C   1 
ATOM   1798 O O   . SER B 2  42  ? -9.42779  -7.02731  36.21956  1.000 29.13357 ? 42  SER B O   1 
ATOM   1799 C CB  . SER B 2  42  ? -6.90527  -5.40124  35.21740  1.000 29.09514 ? 42  SER B CB  1 
ATOM   1800 O OG  . SER B 2  42  ? -6.56376  -6.10905  34.03978  1.000 23.55244 ? 42  SER B OG  1 
ATOM   1801 N N   . ASP B 2  43  ? -7.88549  -8.54919  35.60071  1.000 24.02994 ? 43  ASP B N   1 
ATOM   1802 C CA  . ASP B 2  43  ? -8.88798  -9.59057  35.40403  1.000 21.90200 ? 43  ASP B CA  1 
ATOM   1803 C C   . ASP B 2  43  ? -9.52104  -10.00456 36.72444  1.000 24.58739 ? 43  ASP B C   1 
ATOM   1804 O O   . ASP B 2  43  ? -10.70019 -10.37588 36.76049  1.000 21.94971 ? 43  ASP B O   1 
ATOM   1805 C CB  . ASP B 2  43  ? -8.26289  -10.80856 34.72211  1.000 23.14721 ? 43  ASP B CB  1 
ATOM   1806 C CG  . ASP B 2  43  ? -7.81392  -10.52201 33.30072  1.000 29.77693 ? 43  ASP B CG  1 
ATOM   1807 O OD1 . ASP B 2  43  ? -8.08262  -9.41159  32.79445  1.000 27.98708 ? 43  ASP B OD1 1 
ATOM   1808 O OD2 . ASP B 2  43  ? -7.19186  -11.41521 32.68892  1.000 23.93950 ? 43  ASP B OD2 1 
ATOM   1809 N N   . VAL B 2  44  ? -8.75971  -9.93957  37.81339  1.000 25.96117 ? 44  VAL B N   1 
ATOM   1810 C CA  . VAL B 2  44  ? -9.23860  -10.37907 39.11961  1.000 23.01221 ? 44  VAL B CA  1 
ATOM   1811 C C   . VAL B 2  44  ? -9.94060  -9.25028  39.86578  1.000 23.64617 ? 44  VAL B C   1 
ATOM   1812 O O   . VAL B 2  44  ? -10.96890 -9.47120  40.50842  1.000 26.38892 ? 44  VAL B O   1 
ATOM   1813 C CB  . VAL B 2  44  ? -8.05814  -10.95570 39.92666  1.000 25.32423 ? 44  VAL B CB  1 
ATOM   1814 C CG1 . VAL B 2  44  ? -8.47519  -11.27160 41.36116  1.000 19.05083 ? 44  VAL B CG1 1 
ATOM   1815 C CG2 . VAL B 2  44  ? -7.50965  -12.19557 39.23023  1.000 19.96981 ? 44  VAL B CG2 1 
ATOM   1816 N N   . GLY B 2  45  ? -9.40801  -8.03215  39.79700  1.000 23.56920 ? 45  GLY B N   1 
ATOM   1817 C CA  . GLY B 2  45  ? -10.07404 -6.87787  40.36161  1.000 22.92271 ? 45  GLY B CA  1 
ATOM   1818 C C   . GLY B 2  45  ? -9.70502  -6.53290  41.78742  1.000 23.73022 ? 45  GLY B C   1 
ATOM   1819 O O   . GLY B 2  45  ? -10.27208 -5.58150  42.33997  1.000 25.39108 ? 45  GLY B O   1 
ATOM   1820 N N   . GLU B 2  46  ? -8.77993  -7.26478  42.40274  1.000 24.39317 ? 46  GLU B N   1 
ATOM   1821 C CA  . GLU B 2  46  ? -8.37529  -6.97705  43.77163  1.000 27.00364 ? 46  GLU B CA  1 
ATOM   1822 C C   . GLU B 2  46  ? -6.97725  -7.53140  43.99601  1.000 21.59660 ? 46  GLU B C   1 
ATOM   1823 O O   . GLU B 2  46  ? -6.50494  -8.39472  43.25240  1.000 23.01278 ? 46  GLU B O   1 
ATOM   1824 C CB  . GLU B 2  46  ? -9.36179  -7.56645  44.78768  1.000 23.78676 ? 46  GLU B CB  1 
ATOM   1825 C CG  . GLU B 2  46  ? -9.28141  -9.07897  44.92135  1.000 27.79370 ? 46  GLU B CG  1 
ATOM   1826 C CD  . GLU B 2  46  ? -10.20248 -9.62576  45.99735  1.000 38.39006 ? 46  GLU B CD  1 
ATOM   1827 O OE1 . GLU B 2  46  ? -11.05218 -8.86219  46.50395  1.000 39.81214 ? 46  GLU B OE1 1 
ATOM   1828 O OE2 . GLU B 2  46  ? -10.07879 -10.82284 46.33334  1.000 32.07279 ? 46  GLU B OE2 1 
ATOM   1829 N N   . PHE B 2  47  ? -6.32048  -7.02029  45.03354  1.000 22.01485 ? 47  PHE B N   1 
ATOM   1830 C CA  . PHE B 2  47  ? -4.98581  -7.49176  45.37092  1.000 23.04614 ? 47  PHE B CA  1 
ATOM   1831 C C   . PHE B 2  47  ? -5.03929  -8.93590  45.85051  1.000 26.14028 ? 47  PHE B C   1 
ATOM   1832 O O   . PHE B 2  47  ? -5.93120  -9.32388  46.61062  1.000 28.76425 ? 47  PHE B O   1 
ATOM   1833 C CB  . PHE B 2  47  ? -4.36013  -6.60035  46.44251  1.000 20.76851 ? 47  PHE B CB  1 
ATOM   1834 C CG  . PHE B 2  47  ? -3.93953  -5.25044  45.93603  1.000 22.20319 ? 47  PHE B CG  1 
ATOM   1835 C CD1 . PHE B 2  47  ? -2.73906  -5.09119  45.26340  1.000 27.24637 ? 47  PHE B CD1 1 
ATOM   1836 C CD2 . PHE B 2  47  ? -4.74735  -4.14157  46.12663  1.000 28.33651 ? 47  PHE B CD2 1 
ATOM   1837 C CE1 . PHE B 2  47  ? -2.34951  -3.85021  44.79381  1.000 28.31517 ? 47  PHE B CE1 1 
ATOM   1838 C CE2 . PHE B 2  47  ? -4.36383  -2.89760  45.65911  1.000 25.22508 ? 47  PHE B CE2 1 
ATOM   1839 C CZ  . PHE B 2  47  ? -3.16286  -2.75253  44.99239  1.000 28.86871 ? 47  PHE B CZ  1 
ATOM   1840 N N   . ARG B 2  48  ? -4.07972  -9.73724  45.39367  1.000 23.50706 ? 48  ARG B N   1 
ATOM   1841 C CA  . ARG B 2  48  ? -3.98960  -11.14051 45.77158  1.000 21.49689 ? 48  ARG B CA  1 
ATOM   1842 C C   . ARG B 2  48  ? -2.59191  -11.43118 46.29341  1.000 29.28463 ? 48  ARG B C   1 
ATOM   1843 O O   . ARG B 2  48  ? -1.59769  -11.05737 45.66218  1.000 25.10816 ? 48  ARG B O   1 
ATOM   1844 C CB  . ARG B 2  48  ? -4.32110  -12.05932 44.59142  1.000 22.22618 ? 48  ARG B CB  1 
ATOM   1845 C CG  . ARG B 2  48  ? -5.78463  -12.01409 44.16684  1.000 24.10558 ? 48  ARG B CG  1 
ATOM   1846 C CD  . ARG B 2  48  ? -6.69208  -12.55783 45.26358  1.000 26.94394 ? 48  ARG B CD  1 
ATOM   1847 N NE  . ARG B 2  48  ? -8.10250  -12.51726 44.89331  1.000 27.84830 ? 48  ARG B NE  1 
ATOM   1848 C CZ  . ARG B 2  48  ? -8.71980  -13.45497 44.18763  1.000 27.14011 ? 48  ARG B CZ  1 
ATOM   1849 N NH1 . ARG B 2  48  ? -8.07240  -14.51424 43.73004  1.000 21.51478 ? 48  ARG B NH1 1 
ATOM   1850 N NH2 . ARG B 2  48  ? -10.02161 -13.33139 43.94261  1.000 29.69594 ? 48  ARG B NH2 1 
ATOM   1851 N N   . ALA B 2  49  ? -2.52149  -12.09159 47.44569  1.000 26.38818 ? 49  ALA B N   1 
ATOM   1852 C CA  . ALA B 2  49  ? -1.24453  -12.47296 48.03209  1.000 28.88771 ? 49  ALA B CA  1 
ATOM   1853 C C   . ALA B 2  49  ? -0.67417  -13.66238 47.27158  1.000 25.20224 ? 49  ALA B C   1 
ATOM   1854 O O   . ALA B 2  49  ? -1.33016  -14.70256 47.15105  1.000 27.42320 ? 49  ALA B O   1 
ATOM   1855 C CB  . ALA B 2  49  ? -1.41492  -12.81084 49.51117  1.000 25.64191 ? 49  ALA B CB  1 
ATOM   1856 N N   . VAL B 2  50  ? 0.54236   -13.50797 46.75245  1.000 23.88261 ? 50  VAL B N   1 
ATOM   1857 C CA  . VAL B 2  50  ? 1.20333   -14.62372 46.08627  1.000 26.11013 ? 50  VAL B CA  1 
ATOM   1858 C C   . VAL B 2  50  ? 1.88625   -15.52487 47.10718  1.000 27.56230 ? 50  VAL B C   1 
ATOM   1859 O O   . VAL B 2  50  ? 1.88070   -16.75350 46.97066  1.000 25.56751 ? 50  VAL B O   1 
ATOM   1860 C CB  . VAL B 2  50  ? 2.19316   -14.09746 45.03104  1.000 27.03944 ? 50  VAL B CB  1 
ATOM   1861 C CG1 . VAL B 2  50  ? 2.85279   -15.25210 44.29217  1.000 26.53232 ? 50  VAL B CG1 1 
ATOM   1862 C CG2 . VAL B 2  50  ? 1.48005   -13.17147 44.05628  1.000 25.05368 ? 50  VAL B CG2 1 
ATOM   1863 N N   . THR B 2  51  ? 2.47906   -14.93316 48.14265  1.000 22.63354 ? 51  THR B N   1 
ATOM   1864 C CA  . THR B 2  51  ? 3.10953   -15.66480 49.23119  1.000 27.12132 ? 51  THR B CA  1 
ATOM   1865 C C   . THR B 2  51  ? 2.64398   -15.08176 50.55900  1.000 22.72462 ? 51  THR B C   1 
ATOM   1866 O O   . THR B 2  51  ? 1.99897   -14.03112 50.60990  1.000 21.61472 ? 51  THR B O   1 
ATOM   1867 C CB  . THR B 2  51  ? 4.64237   -15.60780 49.14584  1.000 28.99319 ? 51  THR B CB  1 
ATOM   1868 O OG1 . THR B 2  51  ? 5.07966   -14.25959 49.35167  1.000 27.47737 ? 51  THR B OG1 1 
ATOM   1869 C CG2 . THR B 2  51  ? 5.13398   -16.09844 47.78558  1.000 25.44488 ? 51  THR B CG2 1 
ATOM   1870 N N   . LEU B 2  52  ? 2.99474   -15.77485 51.64657  1.000 24.87502 ? 52  LEU B N   1 
ATOM   1871 C CA  . LEU B 2  52  ? 2.60190   -15.32003 52.97791  1.000 25.80367 ? 52  LEU B CA  1 
ATOM   1872 C C   . LEU B 2  52  ? 3.14907   -13.93249 53.28878  1.000 27.25726 ? 52  LEU B C   1 
ATOM   1873 O O   . LEU B 2  52  ? 2.48912   -13.14625 53.97794  1.000 27.65221 ? 52  LEU B O   1 
ATOM   1874 C CB  . LEU B 2  52  ? 3.07282   -16.32074 54.03464  1.000 24.61840 ? 52  LEU B CB  1 
ATOM   1875 C CG  . LEU B 2  52  ? 2.70847   -15.99400 55.48456  1.000 31.29658 ? 52  LEU B CG  1 
ATOM   1876 C CD1 . LEU B 2  52  ? 1.19704   -15.96121 55.66583  1.000 22.44295 ? 52  LEU B CD1 1 
ATOM   1877 C CD2 . LEU B 2  52  ? 3.34951   -16.98543 56.44353  1.000 27.29238 ? 52  LEU B CD2 1 
ATOM   1878 N N   . LEU B 2  53  ? 4.34548   -13.61236 52.78870  1.000 24.58378 ? 53  LEU B N   1 
ATOM   1879 C CA  . LEU B 2  53  ? 4.94433   -12.30955 53.06298  1.000 27.34220 ? 53  LEU B CA  1 
ATOM   1880 C C   . LEU B 2  53  ? 4.07206   -11.16549 52.55984  1.000 28.33624 ? 53  LEU B C   1 
ATOM   1881 O O   . LEU B 2  53  ? 4.08103   -10.07598 53.14354  1.000 31.07840 ? 53  LEU B O   1 
ATOM   1882 C CB  . LEU B 2  53  ? 6.33624   -12.23491 52.43267  1.000 27.46500 ? 53  LEU B CB  1 
ATOM   1883 C CG  . LEU B 2  53  ? 7.23612   -11.06385 52.83182  1.000 32.14709 ? 53  LEU B CG  1 
ATOM   1884 C CD1 . LEU B 2  53  ? 7.46358   -11.04452 54.33636  1.000 31.03640 ? 53  LEU B CD1 1 
ATOM   1885 C CD2 . LEU B 2  53  ? 8.56290   -11.12888 52.08333  1.000 29.24931 ? 53  LEU B CD2 1 
ATOM   1886 N N   . GLY B 2  54  ? 3.31102   -11.38843 51.49290  1.000 26.03122 ? 54  GLY B N   1 
ATOM   1887 C CA  . GLY B 2  54  ? 2.47234   -10.34829 50.94213  1.000 25.81770 ? 54  GLY B CA  1 
ATOM   1888 C C   . GLY B 2  54  ? 1.04278   -10.30985 51.43278  1.000 25.28794 ? 54  GLY B C   1 
ATOM   1889 O O   . GLY B 2  54  ? 0.29660   -9.40416  51.04809  1.000 22.86545 ? 54  GLY B O   1 
ATOM   1890 N N   . LEU B 2  55  ? 0.63092   -11.25672 52.27629  1.000 25.51320 ? 55  LEU B N   1 
ATOM   1891 C CA  . LEU B 2  55  ? -0.76512  -11.29840 52.70997  1.000 21.91811 ? 55  LEU B CA  1 
ATOM   1892 C C   . LEU B 2  55  ? -1.18464  -10.06498 53.50232  1.000 25.20646 ? 55  LEU B C   1 
ATOM   1893 O O   . LEU B 2  55  ? -2.26796  -9.52383  53.21920  1.000 24.05444 ? 55  LEU B O   1 
ATOM   1894 C CB  . LEU B 2  55  ? -1.02771  -12.58851 53.49560  1.000 23.25539 ? 55  LEU B CB  1 
ATOM   1895 C CG  . LEU B 2  55  ? -2.45024  -12.73889 54.04184  1.000 28.45061 ? 55  LEU B CG  1 
ATOM   1896 C CD1 . LEU B 2  55  ? -3.46560  -12.74489 52.90721  1.000 23.76128 ? 55  LEU B CD1 1 
ATOM   1897 C CD2 . LEU B 2  55  ? -2.58166  -13.99395 54.89527  1.000 27.44213 ? 55  LEU B CD2 1 
ATOM   1898 N N   . PRO B 2  56  ? -0.42019  -9.57269  54.49013  1.000 25.29521 ? 56  PRO B N   1 
ATOM   1899 C CA  . PRO B 2  56  ? -0.86200  -8.34146  55.17472  1.000 28.84607 ? 56  PRO B CA  1 
ATOM   1900 C C   . PRO B 2  56  ? -1.00232  -7.15374  54.23814  1.000 25.83146 ? 56  PRO B C   1 
ATOM   1901 O O   . PRO B 2  56  ? -1.89980  -6.32343  54.42820  1.000 32.13657 ? 56  PRO B O   1 
ATOM   1902 C CB  . PRO B 2  56  ? 0.22038   -8.09540  56.23837  1.000 26.66264 ? 56  PRO B CB  1 
ATOM   1903 C CG  . PRO B 2  56  ? 1.12821   -9.25143  56.21656  1.000 30.57616 ? 56  PRO B CG  1 
ATOM   1904 C CD  . PRO B 2  56  ? 0.71486   -10.22422 55.17104  1.000 28.99689 ? 56  PRO B CD  1 
ATOM   1905 N N   . ALA B 2  57  ? -0.14245  -7.05136  53.22286  1.000 30.63604 ? 57  ALA B N   1 
ATOM   1906 C CA  . ALA B 2  57  ? -0.24670  -5.94515  52.27658  1.000 28.95732 ? 57  ALA B CA  1 
ATOM   1907 C C   . ALA B 2  57  ? -1.51289  -6.05868  51.43553  1.000 30.80225 ? 57  ALA B C   1 
ATOM   1908 O O   . ALA B 2  57  ? -2.23330  -5.07161  51.24275  1.000 25.41242 ? 57  ALA B O   1 
ATOM   1909 C CB  . ALA B 2  57  ? 0.99346   -5.89851  51.38337  1.000 35.75395 ? 57  ALA B CB  1 
ATOM   1910 N N   . ALA B 2  58  ? -1.80249  -7.26063  50.92991  1.000 27.96615 ? 58  ALA B N   1 
ATOM   1911 C CA  . ALA B 2  58  ? -2.97695  -7.44596  50.08297  1.000 25.63021 ? 58  ALA B CA  1 
ATOM   1912 C C   . ALA B 2  58  ? -4.26447  -7.18078  50.85282  1.000 32.96492 ? 58  ALA B C   1 
ATOM   1913 O O   . ALA B 2  58  ? -5.19339  -6.55633  50.32720  1.000 28.33580 ? 58  ALA B O   1 
ATOM   1914 C CB  . ALA B 2  58  ? -2.98403  -8.85764  49.49771  1.000 25.08059 ? 58  ALA B CB  1 
ATOM   1915 N N   . GLU B 2  59  ? -4.33797  -7.64512  52.10190  1.000 30.25610 ? 59  GLU B N   1 
ATOM   1916 C CA  . GLU B 2  59  ? -5.53931  -7.42495  52.90040  1.000 33.01205 ? 59  GLU B CA  1 
ATOM   1917 C C   . GLU B 2  59  ? -5.73398  -5.94629  53.21304  1.000 31.50435 ? 59  GLU B C   1 
ATOM   1918 O O   . GLU B 2  59  ? -6.85921  -5.43680  53.15077  1.000 34.22017 ? 59  GLU B O   1 
ATOM   1919 C CB  . GLU B 2  59  ? -5.46866  -8.24162  54.19051  1.000 31.50432 ? 59  GLU B CB  1 
ATOM   1920 C CG  . GLU B 2  59  ? -5.79497  -9.71387  54.01123  1.000 41.48804 ? 59  GLU B CG  1 
ATOM   1921 C CD  . GLU B 2  59  ? -6.23938  -10.37172 55.30338  1.000 53.59797 ? 59  GLU B CD  1 
ATOM   1922 O OE1 . GLU B 2  59  ? -5.45298  -10.37046 56.27511  1.000 57.10311 ? 59  GLU B OE1 1 
ATOM   1923 O OE2 . GLU B 2  59  ? -7.37626  -10.88785 55.34799  1.000 54.93146 ? 59  GLU B OE2 1 
ATOM   1924 N N   . TYR B 2  60  ? -4.65098  -5.24050  53.54654  1.000 27.85152 ? 60  TYR B N   1 
ATOM   1925 C CA  . TYR B 2  60  ? -4.76462  -3.82259  53.87275  1.000 31.39662 ? 60  TYR B CA  1 
ATOM   1926 C C   . TYR B 2  60  ? -5.20297  -3.00912  52.66066  1.000 34.66633 ? 60  TYR B C   1 
ATOM   1927 O O   . TYR B 2  60  ? -6.17948  -2.25304  52.72970  1.000 34.23545 ? 60  TYR B O   1 
ATOM   1928 C CB  . TYR B 2  60  ? -3.43687  -3.29523  54.41531  1.000 32.90888 ? 60  TYR B CB  1 
ATOM   1929 C CG  . TYR B 2  60  ? -3.41719  -1.79134  54.56642  1.000 42.55882 ? 60  TYR B CG  1 
ATOM   1930 C CD1 . TYR B 2  60  ? -4.29649  -1.15062  55.43057  1.000 43.65524 ? 60  TYR B CD1 1 
ATOM   1931 C CD2 . TYR B 2  60  ? -2.53211  -1.01066  53.83455  1.000 47.03025 ? 60  TYR B CD2 1 
ATOM   1932 C CE1 . TYR B 2  60  ? -4.28870  0.22416   55.56906  1.000 45.21596 ? 60  TYR B CE1 1 
ATOM   1933 C CE2 . TYR B 2  60  ? -2.51684  0.36625   53.96621  1.000 52.76659 ? 60  TYR B CE2 1 
ATOM   1934 C CZ  . TYR B 2  60  ? -3.39737  0.97754   54.83445  1.000 58.44332 ? 60  TYR B CZ  1 
ATOM   1935 O OH  . TYR B 2  60  ? -3.38604  2.34683   54.96909  1.000 70.88966 ? 60  TYR B OH  1 
ATOM   1936 N N   . TRP B 2  61  ? -4.48684  -3.14794  51.54012  1.000 34.25186 ? 61  TRP B N   1 
ATOM   1937 C CA  . TRP B 2  61  ? -4.82758  -2.38574  50.34179  1.000 30.59259 ? 61  TRP B CA  1 
ATOM   1938 C C   . TRP B 2  61  ? -6.24825  -2.68425  49.87990  1.000 28.22039 ? 61  TRP B C   1 
ATOM   1939 O O   . TRP B 2  61  ? -6.94578  -1.79452  49.37853  1.000 30.70404 ? 61  TRP B O   1 
ATOM   1940 C CB  . TRP B 2  61  ? -3.83088  -2.68744  49.22178  1.000 30.37816 ? 61  TRP B CB  1 
ATOM   1941 C CG  . TRP B 2  61  ? -2.41501  -2.31476  49.54130  1.000 31.79876 ? 61  TRP B CG  1 
ATOM   1942 C CD1 . TRP B 2  61  ? -1.99452  -1.37436  50.43659  1.000 32.12445 ? 61  TRP B CD1 1 
ATOM   1943 C CD2 . TRP B 2  61  ? -1.23008  -2.87403  48.96064  1.000 32.68343 ? 61  TRP B CD2 1 
ATOM   1944 N NE1 . TRP B 2  61  ? -0.62090  -1.31578  50.45151  1.000 33.68499 ? 61  TRP B NE1 1 
ATOM   1945 C CE2 . TRP B 2  61  ? -0.12799  -2.22653  49.55416  1.000 37.42576 ? 61  TRP B CE2 1 
ATOM   1946 C CE3 . TRP B 2  61  ? -0.99447  -3.86046  47.99814  1.000 30.10843 ? 61  TRP B CE3 1 
ATOM   1947 C CZ2 . TRP B 2  61  ? 1.18945   -2.53289  49.21553  1.000 35.92632 ? 61  TRP B CZ2 1 
ATOM   1948 C CZ3 . TRP B 2  61  ? 0.31473   -4.16301  47.66267  1.000 29.81852 ? 61  TRP B CZ3 1 
ATOM   1949 C CH2 . TRP B 2  61  ? 1.38917   -3.50162  48.27011  1.000 31.95611 ? 61  TRP B CH2 1 
ATOM   1950 N N   . ASN B 2  62  ? -6.69577  -3.93215  50.04206  1.000 26.71630 ? 62  ASN B N   1 
ATOM   1951 C CA  . ASN B 2  62  ? -8.05513  -4.28635  49.64721  1.000 29.26004 ? 62  ASN B CA  1 
ATOM   1952 C C   . ASN B 2  62  ? -9.09485  -3.60893  50.53158  1.000 37.68507 ? 62  ASN B C   1 
ATOM   1953 O O   . ASN B 2  62  ? -10.22651 -3.37945  50.08932  1.000 36.73855 ? 62  ASN B O   1 
ATOM   1954 C CB  . ASN B 2  62  ? -8.23618  -5.80385  49.68505  1.000 26.73448 ? 62  ASN B CB  1 
ATOM   1955 C CG  . ASN B 2  62  ? -7.76911  -6.47808  48.40924  1.000 27.74669 ? 62  ASN B CG  1 
ATOM   1956 O OD1 . ASN B 2  62  ? -7.44412  -5.81318  47.42584  1.000 24.50318 ? 62  ASN B OD1 1 
ATOM   1957 N ND2 . ASN B 2  62  ? -7.73475  -7.80541  48.41902  1.000 22.54923 ? 62  ASN B ND2 1 
ATOM   1958 N N   . SER B 2  63  ? -8.73660  -3.28404  51.77490  1.000 33.44166 ? 63  SER B N   1 
ATOM   1959 C CA  . SER B 2  63  ? -9.65577  -2.60525  52.67851  1.000 36.57624 ? 63  SER B CA  1 
ATOM   1960 C C   . SER B 2  63  ? -9.75852  -1.11011  52.40699  1.000 42.59818 ? 63  SER B C   1 
ATOM   1961 O O   . SER B 2  63  ? -10.66901 -0.46441  52.93620  1.000 38.17276 ? 63  SER B O   1 
ATOM   1962 C CB  . SER B 2  63  ? -9.23062  -2.83272  54.13166  1.000 32.22946 ? 63  SER B CB  1 
ATOM   1963 O OG  . SER B 2  63  ? -8.19995  -1.93570  54.50798  1.000 37.27870 ? 63  SER B OG  1 
ATOM   1964 N N   . GLN B 2  64  ? -8.85703  -0.54881  51.60488  1.000 38.12336 ? 64  GLN B N   1 
ATOM   1965 C CA  . GLN B 2  64  ? -8.88125  0.86991   51.27411  1.000 38.16843 ? 64  GLN B CA  1 
ATOM   1966 C C   . GLN B 2  64  ? -9.68051  1.07049   49.99124  1.000 46.98168 ? 64  GLN B C   1 
ATOM   1967 O O   . GLN B 2  64  ? -9.27523  0.60234   48.92098  1.000 39.33719 ? 64  GLN B O   1 
ATOM   1968 C CB  . GLN B 2  64  ? -7.46128  1.40982   51.11627  1.000 45.09680 ? 64  GLN B CB  1 
ATOM   1969 C CG  . GLN B 2  64  ? -6.69374  1.53507   52.42105  1.000 44.30200 ? 64  GLN B CG  1 
ATOM   1970 C CD  . GLN B 2  64  ? -7.50975  2.19144   53.51690  1.000 56.10779 ? 64  GLN B CD  1 
ATOM   1971 O OE1 . GLN B 2  64  ? -7.76075  3.39636   53.48227  1.000 61.40664 ? 64  GLN B OE1 1 
ATOM   1972 N NE2 . GLN B 2  64  ? -7.92687  1.40063   54.49944  1.000 49.78702 ? 64  GLN B NE2 1 
ATOM   1973 N N   . LYS B 2  65  ? -10.81012 1.77429   50.10040  1.000 45.13335 ? 65  LYS B N   1 
ATOM   1974 C CA  . LYS B 2  65  ? -11.70511 1.92765   48.95721  1.000 43.38579 ? 65  LYS B CA  1 
ATOM   1975 C C   . LYS B 2  65  ? -11.09400 2.81696   47.88047  1.000 43.57751 ? 65  LYS B C   1 
ATOM   1976 O O   . LYS B 2  65  ? -11.26286 2.55510   46.68364  1.000 38.00876 ? 65  LYS B O   1 
ATOM   1977 C CB  . LYS B 2  65  ? -13.04922 2.48969   49.41997  1.000 43.84811 ? 65  LYS B CB  1 
ATOM   1978 C CG  . LYS B 2  65  ? -14.03618 2.75124   48.29459  1.000 52.33629 ? 65  LYS B CG  1 
ATOM   1979 C CD  . LYS B 2  65  ? -15.42466 2.23993   48.64385  1.000 70.11655 ? 65  LYS B CD  1 
ATOM   1980 C CE  . LYS B 2  65  ? -16.45883 2.72720   47.64083  1.000 68.77976 ? 65  LYS B CE  1 
ATOM   1981 N NZ  . LYS B 2  65  ? -17.81421 2.18111   47.92774  1.000 67.13827 ? 65  LYS B NZ  1 
ATOM   1982 N N   . ASP B 2  66  ? -10.38651 3.87585   48.28187  1.000 41.77304 ? 66  ASP B N   1 
ATOM   1983 C CA  . ASP B 2  66  ? -9.79324  4.77545   47.29759  1.000 44.83153 ? 66  ASP B CA  1 
ATOM   1984 C C   . ASP B 2  66  ? -8.66251  4.10378   46.52756  1.000 42.37253 ? 66  ASP B C   1 
ATOM   1985 O O   . ASP B 2  66  ? -8.47592  4.38279   45.33768  1.000 42.52566 ? 66  ASP B O   1 
ATOM   1986 C CB  . ASP B 2  66  ? -9.29327  6.04872   47.98092  1.000 41.85948 ? 66  ASP B CB  1 
ATOM   1987 C CG  . ASP B 2  66  ? -8.21590  5.77357   49.01121  1.000 51.03882 ? 66  ASP B CG  1 
ATOM   1988 O OD1 . ASP B 2  66  ? -8.43000  4.90224   49.88036  1.000 57.79599 ? 66  ASP B OD1 1 
ATOM   1989 O OD2 . ASP B 2  66  ? -7.15483  6.42953   48.95281  1.000 59.48537 ? 66  ASP B OD2 1 
ATOM   1990 N N   . ILE B 2  67  ? -7.90427  3.21980   47.18005  1.000 41.97297 ? 67  ILE B N   1 
ATOM   1991 C CA  . ILE B 2  67  ? -6.83941  2.50393   46.48472  1.000 39.89061 ? 67  ILE B CA  1 
ATOM   1992 C C   . ILE B 2  67  ? -7.42622  1.53237   45.46868  1.000 38.07852 ? 67  ILE B C   1 
ATOM   1993 O O   . ILE B 2  67  ? -6.95555  1.44706   44.32768  1.000 34.39079 ? 67  ILE B O   1 
ATOM   1994 C CB  . ILE B 2  67  ? -5.92725  1.78459   47.49533  1.000 37.63886 ? 67  ILE B CB  1 
ATOM   1995 C CG1 . ILE B 2  67  ? -5.25023  2.79756   48.41987  1.000 39.53590 ? 67  ILE B CG1 1 
ATOM   1996 C CG2 . ILE B 2  67  ? -4.88201  0.94735   46.77205  1.000 35.16509 ? 67  ILE B CG2 1 
ATOM   1997 C CD1 . ILE B 2  67  ? -4.32638  2.16760   49.44137  1.000 42.48601 ? 67  ILE B CD1 1 
ATOM   1998 N N   . LEU B 2  68  ? -8.46338  0.78794   45.86303  1.000 34.54360 ? 68  LEU B N   1 
ATOM   1999 C CA  . LEU B 2  68  ? -9.09652  -0.15111  44.94198  1.000 37.16820 ? 68  LEU B CA  1 
ATOM   2000 C C   . LEU B 2  68  ? -9.67846  0.56983   43.73388  1.000 39.74514 ? 68  LEU B C   1 
ATOM   2001 O O   . LEU B 2  68  ? -9.56977  0.08692   42.60015  1.000 39.12221 ? 68  LEU B O   1 
ATOM   2002 C CB  . LEU B 2  68  ? -10.18631 -0.94054  45.66535  1.000 34.76778 ? 68  LEU B CB  1 
ATOM   2003 C CG  . LEU B 2  68  ? -9.77714  -2.26040  46.31881  1.000 38.06374 ? 68  LEU B CG  1 
ATOM   2004 C CD1 . LEU B 2  68  ? -11.00754 -3.00548  46.80902  1.000 40.03274 ? 68  LEU B CD1 1 
ATOM   2005 C CD2 . LEU B 2  68  ? -8.97553  -3.11959  45.35301  1.000 31.65707 ? 68  LEU B CD2 1 
ATOM   2006 N N   . GLU B 2  69  ? -10.30033 1.72971   43.95911  1.000 36.18410 ? 69  GLU B N   1 
ATOM   2007 C CA  . GLU B 2  69  ? -10.85853 2.50146   42.85429  1.000 43.78703 ? 69  GLU B CA  1 
ATOM   2008 C C   . GLU B 2  69  ? -9.77185  2.93174   41.87670  1.000 37.82971 ? 69  GLU B C   1 
ATOM   2009 O O   . GLU B 2  69  ? -9.95372  2.84344   40.65678  1.000 37.06397 ? 69  GLU B O   1 
ATOM   2010 C CB  . GLU B 2  69  ? -11.60868 3.71868   43.39573  1.000 41.23323 ? 69  GLU B CB  1 
ATOM   2011 C CG  . GLU B 2  69  ? -12.31833 4.54003   42.33268  1.000 54.35784 ? 69  GLU B CG  1 
ATOM   2012 C CD  . GLU B 2  69  ? -13.40242 5.42910   42.91151  1.000 73.13587 ? 69  GLU B CD  1 
ATOM   2013 O OE1 . GLU B 2  69  ? -14.58533 5.02876   42.87638  1.000 75.44020 ? 69  GLU B OE1 1 
ATOM   2014 O OE2 . GLU B 2  69  ? -13.07066 6.52811   43.40399  1.000 79.02530 ? 69  GLU B OE2 1 
ATOM   2015 N N   . ARG B 2  70  ? -8.63118  3.39557   42.39257  1.000 39.69674 ? 70  ARG B N   1 
ATOM   2016 C CA  . ARG B 2  70  ? -7.54652  3.81568   41.51149  1.000 41.46836 ? 70  ARG B CA  1 
ATOM   2017 C C   . ARG B 2  70  ? -6.96399  2.63284   40.74678  1.000 38.15434 ? 70  ARG B C   1 
ATOM   2018 O O   . ARG B 2  70  ? -6.66689  2.74565   39.55137  1.000 38.09193 ? 70  ARG B O   1 
ATOM   2019 C CB  . ARG B 2  70  ? -6.45457  4.52244   42.31400  1.000 43.76451 ? 70  ARG B CB  1 
ATOM   2020 C CG  . ARG B 2  70  ? -5.27778  4.96064   41.45879  1.000 51.90573 ? 70  ARG B CG  1 
ATOM   2021 C CD  . ARG B 2  70  ? -4.13727  5.54088   42.28882  1.000 56.90376 ? 70  ARG B CD  1 
ATOM   2022 N NE  . ARG B 2  70  ? -3.24824  4.54351   42.88431  1.000 56.59944 ? 70  ARG B NE  1 
ATOM   2023 C CZ  . ARG B 2  70  ? -2.63962  3.55334   42.23927  1.000 54.32659 ? 70  ARG B CZ  1 
ATOM   2024 N NH1 . ARG B 2  70  ? -2.78161  3.37566   40.93467  1.000 48.08888 ? 70  ARG B NH1 1 
ATOM   2025 N NH2 . ARG B 2  70  ? -1.85311  2.72518   42.92138  1.000 50.85015 ? 70  ARG B NH2 1 
ATOM   2026 N N   . LYS B 2  71  ? -6.79524  1.49037   41.41802  1.000 34.77862 ? 71  LYS B N   1 
ATOM   2027 C CA  . LYS B 2  71  ? -6.24803  0.31268   40.75120  1.000 34.32047 ? 71  LYS B CA  1 
ATOM   2028 C C   . LYS B 2  71  ? -7.17563  -0.18402  39.64922  1.000 34.93139 ? 71  LYS B C   1 
ATOM   2029 O O   . LYS B 2  71  ? -6.71315  -0.60231  38.58076  1.000 28.94412 ? 71  LYS B O   1 
ATOM   2030 C CB  . LYS B 2  71  ? -5.99035  -0.79688  41.77087  1.000 28.52952 ? 71  LYS B CB  1 
ATOM   2031 C CG  . LYS B 2  71  ? -4.83144  -0.52169  42.71017  1.000 30.67048 ? 71  LYS B CG  1 
ATOM   2032 C CD  . LYS B 2  71  ? -3.57848  -0.13220  41.94286  1.000 36.73245 ? 71  LYS B CD  1 
ATOM   2033 C CE  . LYS B 2  71  ? -2.80430  -1.35641  41.48072  1.000 34.00006 ? 71  LYS B CE  1 
ATOM   2034 N NZ  . LYS B 2  71  ? -1.37373  -1.03372  41.21347  1.000 33.14375 ? 71  LYS B NZ  1 
ATOM   2035 N N   . ARG B 2  72  ? -8.48966  -0.14604  39.88968  1.000 31.73655 ? 72  ARG B N   1 
ATOM   2036 C CA  . ARG B 2  72  ? -9.43944  -0.64431  38.89893  1.000 28.75186 ? 72  ARG B CA  1 
ATOM   2037 C C   . ARG B 2  72  ? -9.47714  0.23660   37.65635  1.000 29.39750 ? 72  ARG B C   1 
ATOM   2038 O O   . ARG B 2  72  ? -9.80627  -0.24550  36.56628  1.000 25.51628 ? 72  ARG B O   1 
ATOM   2039 C CB  . ARG B 2  72  ? -10.83443 -0.75338  39.51636  1.000 32.23683 ? 72  ARG B CB  1 
ATOM   2040 C CG  . ARG B 2  72  ? -11.17116 -2.13983  40.04481  1.000 33.41183 ? 72  ARG B CG  1 
ATOM   2041 C CD  . ARG B 2  72  ? -12.03221 -2.06969  41.30037  1.000 30.64089 ? 72  ARG B CD  1 
ATOM   2042 N NE  . ARG B 2  72  ? -12.16032 -3.37276  41.94308  1.000 31.05590 ? 72  ARG B NE  1 
ATOM   2043 C CZ  . ARG B 2  72  ? -12.80492 -3.59020  43.08201  1.000 41.36308 ? 72  ARG B CZ  1 
ATOM   2044 N NH1 . ARG B 2  72  ? -13.40027 -2.60760  43.73899  1.000 33.07847 ? 72  ARG B NH1 1 
ATOM   2045 N NH2 . ARG B 2  72  ? -12.85341 -4.82506  43.57456  1.000 27.70343 ? 72  ARG B NH2 1 
ATOM   2046 N N   . ALA B 2  73  ? -9.15264  1.51983   37.79536  1.000 28.90172 ? 73  ALA B N   1 
ATOM   2047 C CA  . ALA B 2  73  ? -9.07299  2.41807   36.65285  1.000 32.54862 ? 73  ALA B CA  1 
ATOM   2048 C C   . ALA B 2  73  ? -7.70498  2.40858   35.98402  1.000 34.50740 ? 73  ALA B C   1 
ATOM   2049 O O   . ALA B 2  73  ? -7.56519  2.96975   34.89172  1.000 31.36760 ? 73  ALA B O   1 
ATOM   2050 C CB  . ALA B 2  73  ? -9.41860  3.84891   37.07941  1.000 29.88995 ? 73  ALA B CB  1 
ATOM   2051 N N   . ALA B 2  74  ? -6.70576  1.77033   36.60233  1.000 32.01011 ? 74  ALA B N   1 
ATOM   2052 C CA  . ALA B 2  74  ? -5.33410  1.86433   36.11169  1.000 27.76148 ? 74  ALA B CA  1 
ATOM   2053 C C   . ALA B 2  74  ? -5.17742  1.26708   34.72048  1.000 30.94290 ? 74  ALA B C   1 
ATOM   2054 O O   . ALA B 2  74  ? -4.35329  1.74610   33.93291  1.000 26.28021 ? 74  ALA B O   1 
ATOM   2055 C CB  . ALA B 2  74  ? -4.37970  1.17820   37.08878  1.000 29.98039 ? 74  ALA B CB  1 
ATOM   2056 N N   . VAL B 2  75  ? -5.94899  0.22571   34.39774  1.000 30.84572 ? 75  VAL B N   1 
ATOM   2057 C CA  . VAL B 2  75  ? -5.83609  -0.39401  33.08061  1.000 22.83007 ? 75  VAL B CA  1 
ATOM   2058 C C   . VAL B 2  75  ? -6.23768  0.58796   31.98732  1.000 32.39391 ? 75  VAL B C   1 
ATOM   2059 O O   . VAL B 2  75  ? -5.76794  0.48750   30.84694  1.000 30.34676 ? 75  VAL B O   1 
ATOM   2060 C CB  . VAL B 2  75  ? -6.67237  -1.69059  33.02742  1.000 33.00861 ? 75  VAL B CB  1 
ATOM   2061 C CG1 . VAL B 2  75  ? -8.16301  -1.38425  33.15390  1.000 26.56314 ? 75  VAL B CG1 1 
ATOM   2062 C CG2 . VAL B 2  75  ? -6.37798  -2.47224  31.75224  1.000 26.52403 ? 75  VAL B CG2 1 
ATOM   2063 N N   . ASP B 2  76  ? -7.09306  1.55828   32.31205  1.000 29.50479 ? 76  ASP B N   1 
ATOM   2064 C CA  . ASP B 2  76  ? -7.47417  2.58624   31.35147  1.000 31.15710 ? 76  ASP B CA  1 
ATOM   2065 C C   . ASP B 2  76  ? -6.58543  3.82015   31.44764  1.000 30.20412 ? 76  ASP B C   1 
ATOM   2066 O O   . ASP B 2  76  ? -6.17975  4.37174   30.41905  1.000 35.21840 ? 76  ASP B O   1 
ATOM   2067 C CB  . ASP B 2  76  ? -8.93891  2.98808   31.55296  1.000 28.81442 ? 76  ASP B CB  1 
ATOM   2068 C CG  . ASP B 2  76  ? -9.88183  1.80008   31.52921  1.000 29.67622 ? 76  ASP B CG  1 
ATOM   2069 O OD1 . ASP B 2  76  ? -9.70766  0.91304   30.66730  1.000 31.70420 ? 76  ASP B OD1 1 
ATOM   2070 O OD2 . ASP B 2  76  ? -10.80395 1.75764   32.37076  1.000 32.53032 ? 76  ASP B OD2 1 
ATOM   2071 N N   . ARG B 2  77  ? -6.26883  4.26122   32.66731  1.000 32.17055 ? 77  ARG B N   1 
ATOM   2072 C CA  . ARG B 2  77  ? -5.47026  5.46838   32.84335  1.000 33.33172 ? 77  ARG B CA  1 
ATOM   2073 C C   . ARG B 2  77  ? -3.99893  5.25469   32.51111  1.000 37.38392 ? 77  ARG B C   1 
ATOM   2074 O O   . ARG B 2  77  ? -3.27192  6.23726   32.33058  1.000 29.33169 ? 77  ARG B O   1 
ATOM   2075 C CB  . ARG B 2  77  ? -5.60064  5.98510   34.27799  1.000 29.98369 ? 77  ARG B CB  1 
ATOM   2076 C CG  . ARG B 2  77  ? -7.03267  6.09899   34.78007  1.000 47.74229 ? 77  ARG B CG  1 
ATOM   2077 C CD  . ARG B 2  77  ? -7.30239  7.47063   35.37870  1.000 54.04378 ? 77  ARG B CD  1 
ATOM   2078 N NE  . ARG B 2  77  ? -6.94072  7.53433   36.79033  1.000 66.71078 ? 77  ARG B NE  1 
ATOM   2079 C CZ  . ARG B 2  77  ? -7.81257  7.62544   37.78572  1.000 73.26442 ? 77  ARG B CZ  1 
ATOM   2080 N NH1 . ARG B 2  77  ? -9.11630  7.65900   37.56212  1.000 72.95263 ? 77  ARG B NH1 1 
ATOM   2081 N NH2 . ARG B 2  77  ? -7.36500  7.68514   39.03712  1.000 61.25578 ? 77  ARG B NH2 1 
ATOM   2082 N N   . VAL B 2  78  ? -3.53988  4.00617   32.43339  1.000 32.60716 ? 78  VAL B N   1 
ATOM   2083 C CA  . VAL B 2  78  ? -2.13276  3.73506   32.15996  1.000 31.06588 ? 78  VAL B CA  1 
ATOM   2084 C C   . VAL B 2  78  ? -1.99308  2.95295   30.86048  1.000 31.89016 ? 78  VAL B C   1 
ATOM   2085 O O   . VAL B 2  78  ? -1.41683  3.45024   29.88649  1.000 30.53746 ? 78  VAL B O   1 
ATOM   2086 C CB  . VAL B 2  78  ? -1.46732  2.98172   33.32702  1.000 30.90327 ? 78  VAL B CB  1 
ATOM   2087 C CG1 . VAL B 2  78  ? -0.00893  2.68694   33.00346  1.000 28.34780 ? 78  VAL B CG1 1 
ATOM   2088 C CG2 . VAL B 2  78  ? -1.57576  3.78731   34.61223  1.000 32.38895 ? 78  VAL B CG2 1 
ATOM   2089 N N   . CYS B 2  79  ? -2.52552  1.72820   30.83352  1.000 28.39247 ? 79  CYS B N   1 
ATOM   2090 C CA  . CYS B 2  79  ? -2.29268  0.84142   29.69593  1.000 27.85254 ? 79  CYS B CA  1 
ATOM   2091 C C   . CYS B 2  79  ? -2.94642  1.37422   28.42493  1.000 35.66058 ? 79  CYS B C   1 
ATOM   2092 O O   . CYS B 2  79  ? -2.28091  1.53032   27.39376  1.000 30.29871 ? 79  CYS B O   1 
ATOM   2093 C CB  . CYS B 2  79  ? -2.80263  -0.56344  30.01183  1.000 24.03667 ? 79  CYS B CB  1 
ATOM   2094 S SG  . CYS B 2  79  ? -2.08179  -1.33048  31.47589  1.000 27.99011 ? 79  CYS B SG  1 
ATOM   2095 N N   . ARG B 2  80  ? -4.25523  1.64255   28.47282  1.000 29.99244 ? 80  ARG B N   1 
ATOM   2096 C CA  . ARG B 2  80  ? -4.94637  2.15838   27.29337  1.000 31.45554 ? 80  ARG B CA  1 
ATOM   2097 C C   . ARG B 2  80  ? -4.42456  3.53511   26.90659  1.000 24.72424 ? 80  ARG B C   1 
ATOM   2098 O O   . ARG B 2  80  ? -4.25515  3.83339   25.71836  1.000 32.64593 ? 80  ARG B O   1 
ATOM   2099 C CB  . ARG B 2  80  ? -6.45431  2.22035   27.54334  1.000 28.27418 ? 80  ARG B CB  1 
ATOM   2100 C CG  . ARG B 2  80  ? -7.16316  0.87972   27.50960  1.000 36.31542 ? 80  ARG B CG  1 
ATOM   2101 C CD  . ARG B 2  80  ? -8.66536  1.05404   27.29627  1.000 28.22082 ? 80  ARG B CD  1 
ATOM   2102 N NE  . ARG B 2  80  ? -9.42657  0.01543   27.97888  1.000 29.34498 ? 80  ARG B NE  1 
ATOM   2103 C CZ  . ARG B 2  80  ? -9.75035  -1.15177  27.44009  1.000 28.32900 ? 80  ARG B CZ  1 
ATOM   2104 N NH1 . ARG B 2  80  ? -9.41035  -1.45765  26.19947  1.000 29.25915 ? 80  ARG B NH1 1 
ATOM   2105 N NH2 . ARG B 2  80  ? -10.42967 -2.03551  28.16604  1.000 40.15161 ? 80  ARG B NH2 1 
ATOM   2106 N N   . HIS B 2  81  ? -4.17530  4.39016   27.89994  1.000 28.10936 ? 81  HIS B N   1 
ATOM   2107 C CA  . HIS B 2  81  ? -3.68963  5.73729   27.62480  1.000 28.99506 ? 81  HIS B CA  1 
ATOM   2108 C C   . HIS B 2  81  ? -2.34897  5.70469   26.90152  1.000 35.19686 ? 81  HIS B C   1 
ATOM   2109 O O   . HIS B 2  81  ? -2.13588  6.45111   25.93827  1.000 33.90571 ? 81  HIS B O   1 
ATOM   2110 C CB  . HIS B 2  81  ? -3.58438  6.51817   28.93542  1.000 28.74981 ? 81  HIS B CB  1 
ATOM   2111 C CG  . HIS B 2  81  ? -3.01717  7.89516   28.78457  1.000 38.78743 ? 81  HIS B CG  1 
ATOM   2112 N ND1 . HIS B 2  81  ? -1.66217  8.14036   28.71797  1.000 39.53528 ? 81  HIS B ND1 1 
ATOM   2113 C CD2 . HIS B 2  81  ? -3.62218  9.10391   28.70667  1.000 37.82636 ? 81  HIS B CD2 1 
ATOM   2114 C CE1 . HIS B 2  81  ? -1.45749  9.43970   28.59612  1.000 39.75804 ? 81  HIS B CE1 1 
ATOM   2115 N NE2 . HIS B 2  81  ? -2.63055  10.04698  28.58715  1.000 48.40384 ? 81  HIS B NE2 1 
ATOM   2116 N N   . ASN B 2  82  ? -1.43943  4.83081   27.33810  1.000 30.55604 ? 82  ASN B N   1 
ATOM   2117 C CA  . ASN B 2  82  ? -0.09772  4.80695   26.76760  1.000 31.74694 ? 82  ASN B CA  1 
ATOM   2118 C C   . ASN B 2  82  ? -0.05098  4.11445   25.41127  1.000 29.47777 ? 82  ASN B C   1 
ATOM   2119 O O   . ASN B 2  82  ? 0.84463   4.40377   24.61123  1.000 32.51323 ? 82  ASN B O   1 
ATOM   2120 C CB  . ASN B 2  82  ? 0.87318   4.13130   27.73784  1.000 22.99653 ? 82  ASN B CB  1 
ATOM   2121 C CG  . ASN B 2  82  ? 1.27683   5.03840   28.88369  1.000 29.05507 ? 82  ASN B CG  1 
ATOM   2122 O OD1 . ASN B 2  82  ? 0.87129   6.19892   28.94294  1.000 32.73958 ? 82  ASN B OD1 1 
ATOM   2123 N ND2 . ASN B 2  82  ? 2.08061   4.51322   29.80126  1.000 28.62810 ? 82  ASN B ND2 1 
ATOM   2124 N N   . TYR B 2  83  ? -0.99152  3.20730   25.12903  1.000 32.42055 ? 83  TYR B N   1 
ATOM   2125 C CA  . TYR B 2  83  ? -0.99910  2.54857   23.82550  1.000 30.71694 ? 83  TYR B CA  1 
ATOM   2126 C C   . TYR B 2  83  ? -1.23854  3.54362   22.69848  1.000 35.09672 ? 83  TYR B C   1 
ATOM   2127 O O   . TYR B 2  83  ? -0.76630  3.33480   21.57434  1.000 29.24227 ? 83  TYR B O   1 
ATOM   2128 C CB  . TYR B 2  83  ? -2.05635  1.44450   23.78863  1.000 25.15297 ? 83  TYR B CB  1 
ATOM   2129 C CG  . TYR B 2  83  ? -1.83908  0.43297   22.68377  1.000 27.35431 ? 83  TYR B CG  1 
ATOM   2130 C CD1 . TYR B 2  83  ? -1.00110  -0.65942  22.86906  1.000 32.02511 ? 83  TYR B CD1 1 
ATOM   2131 C CD2 . TYR B 2  83  ? -2.46642  0.57496   21.45227  1.000 31.92870 ? 83  TYR B CD2 1 
ATOM   2132 C CE1 . TYR B 2  83  ? -0.79858  -1.58574  21.86029  1.000 31.41578 ? 83  TYR B CE1 1 
ATOM   2133 C CE2 . TYR B 2  83  ? -2.26991  -0.34396  20.43908  1.000 28.95486 ? 83  TYR B CE2 1 
ATOM   2134 C CZ  . TYR B 2  83  ? -1.43519  -1.42145  20.64727  1.000 32.17377 ? 83  TYR B CZ  1 
ATOM   2135 O OH  . TYR B 2  83  ? -1.23932  -2.33726  19.63866  1.000 28.39172 ? 83  TYR B OH  1 
ATOM   2136 N N   . GLN B 2  84  ? -1.96984  4.62519   22.97583  1.000 32.33348 ? 84  GLN B N   1 
ATOM   2137 C CA  . GLN B 2  84  ? -2.13971  5.67431   21.97720  1.000 37.10524 ? 84  GLN B CA  1 
ATOM   2138 C C   . GLN B 2  84  ? -0.80466  6.32815   21.64362  1.000 36.44255 ? 84  GLN B C   1 
ATOM   2139 O O   . GLN B 2  84  ? -0.53153  6.64520   20.47978  1.000 32.19283 ? 84  GLN B O   1 
ATOM   2140 C CB  . GLN B 2  84  ? -3.14618  6.71151   22.47775  1.000 35.83854 ? 84  GLN B CB  1 
ATOM   2141 C CG  . GLN B 2  84  ? -3.11795  8.03152   21.72811  1.000 38.57609 ? 84  GLN B CG  1 
ATOM   2142 C CD  . GLN B 2  84  ? -3.95073  7.99959   20.46572  1.000 48.95588 ? 84  GLN B CD  1 
ATOM   2143 O OE1 . GLN B 2  84  ? -3.49110  7.54862   19.41608  1.000 59.22075 ? 84  GLN B OE1 1 
ATOM   2144 N NE2 . GLN B 2  84  ? -5.18571  8.47986   20.55960  1.000 60.50426 ? 84  GLN B NE2 1 
ATOM   2145 N N   . LEU B 2  85  ? 0.04744   6.52422   22.65288  1.000 35.90196 ? 85  LEU B N   1 
ATOM   2146 C CA  . LEU B 2  85  ? 1.36656   7.09566   22.40491  1.000 33.51984 ? 85  LEU B CA  1 
ATOM   2147 C C   . LEU B 2  85  ? 2.27064   6.10741   21.67846  1.000 33.40532 ? 85  LEU B C   1 
ATOM   2148 O O   . LEU B 2  85  ? 3.09030   6.50771   20.84359  1.000 37.00186 ? 85  LEU B O   1 
ATOM   2149 C CB  . LEU B 2  85  ? 2.00159   7.54133   23.72142  1.000 33.05616 ? 85  LEU B CB  1 
ATOM   2150 C CG  . LEU B 2  85  ? 1.28026   8.67400   24.45240  1.000 37.85123 ? 85  LEU B CG  1 
ATOM   2151 C CD1 . LEU B 2  85  ? 1.81131   8.82201   25.86585  1.000 39.84339 ? 85  LEU B CD1 1 
ATOM   2152 C CD2 . LEU B 2  85  ? 1.41503   9.97980   23.68608  1.000 43.26655 ? 85  LEU B CD2 1 
ATOM   2153 N N   . GLU B 2  86  ? 2.13915   4.81302   21.98069  1.000 30.23528 ? 86  GLU B N   1 
ATOM   2154 C CA  . GLU B 2  86  ? 2.93376   3.81245   21.27488  1.000 29.23465 ? 86  GLU B CA  1 
ATOM   2155 C C   . GLU B 2  86  ? 2.53580   3.72900   19.80678  1.000 37.05740 ? 86  GLU B C   1 
ATOM   2156 O O   . GLU B 2  86  ? 3.39188   3.52615   18.93622  1.000 28.38586 ? 86  GLU B O   1 
ATOM   2157 C CB  . GLU B 2  86  ? 2.78645   2.44536   21.94518  1.000 26.92290 ? 86  GLU B CB  1 
ATOM   2158 C CG  . GLU B 2  86  ? 3.06273   2.42882   23.44522  1.000 26.76877 ? 86  GLU B CG  1 
ATOM   2159 C CD  . GLU B 2  86  ? 4.52221   2.67168   23.79284  1.000 28.34314 ? 86  GLU B CD  1 
ATOM   2160 O OE1 . GLU B 2  86  ? 5.36709   2.70407   22.87370  1.000 29.36830 ? 86  GLU B OE1 1 
ATOM   2161 O OE2 . GLU B 2  86  ? 4.82679   2.82059   24.99530  1.000 30.86868 ? 86  GLU B OE2 1 
ATOM   2162 N N   . LEU B 2  87  ? 1.24004   3.88497   19.51477  1.000 31.06233 ? 87  LEU B N   1 
ATOM   2163 C CA  . LEU B 2  87  ? 0.77256   3.83849   18.13292  1.000 31.63037 ? 87  LEU B CA  1 
ATOM   2164 C C   . LEU B 2  87  ? 1.41375   4.92795   17.28551  1.000 34.40816 ? 87  LEU B C   1 
ATOM   2165 O O   . LEU B 2  87  ? 1.56840   4.75907   16.07082  1.000 39.68195 ? 87  LEU B O   1 
ATOM   2166 C CB  . LEU B 2  87  ? -0.75034  3.96850   18.08879  1.000 37.16362 ? 87  LEU B CB  1 
ATOM   2167 C CG  . LEU B 2  87  ? -1.57055  2.69927   18.32246  1.000 32.85533 ? 87  LEU B CG  1 
ATOM   2168 C CD1 . LEU B 2  87  ? -3.02847  3.04854   18.57078  1.000 35.74673 ? 87  LEU B CD1 1 
ATOM   2169 C CD2 . LEU B 2  87  ? -1.43674  1.75256   17.14267  1.000 30.49716 ? 87  LEU B CD2 1 
ATOM   2170 N N   . ARG B 2  88  ? 1.79343   6.04407   17.90257  1.000 32.33129 ? 88  ARG B N   1 
ATOM   2171 C CA  . ARG B 2  88  ? 2.41550   7.15621   17.20123  1.000 40.02997 ? 88  ARG B CA  1 
ATOM   2172 C C   . ARG B 2  88  ? 3.93745   7.11954   17.25586  1.000 43.41359 ? 88  ARG B C   1 
ATOM   2173 O O   . ARG B 2  88  ? 4.58402   7.96432   16.62892  1.000 43.26639 ? 88  ARG B O   1 
ATOM   2174 C CB  . ARG B 2  88  ? 1.90729   8.48383   17.77495  1.000 39.86465 ? 88  ARG B CB  1 
ATOM   2175 C CG  . ARG B 2  88  ? 0.39777   8.65546   17.67269  1.000 47.91725 ? 88  ARG B CG  1 
ATOM   2176 C CD  . ARG B 2  88  ? -0.06168  10.00991  18.19496  1.000 56.92750 ? 88  ARG B CD  1 
ATOM   2177 N NE  . ARG B 2  88  ? 0.94647   10.65842  19.02499  1.000 62.12960 ? 88  ARG B NE  1 
ATOM   2178 C CZ  . ARG B 2  88  ? 1.05927   11.97113  19.17669  1.000 76.05024 ? 88  ARG B CZ  1 
ATOM   2179 N NH1 . ARG B 2  88  ? 0.24046   12.81077  18.56379  1.000 76.25998 ? 88  ARG B NH1 1 
ATOM   2180 N NH2 . ARG B 2  88  ? 2.01692   12.45368  19.96373  1.000 66.63943 ? 88  ARG B NH2 1 
ATOM   2181 N N   . THR B 2  89  ? 4.52537   6.16679   17.98304  1.000 39.12525 ? 89  THR B N   1 
ATOM   2182 C CA  . THR B 2  89  ? 5.97693   6.09882   18.11497  1.000 30.19742 ? 89  THR B CA  1 
ATOM   2183 C C   . THR B 2  89  ? 6.50884   4.69873   17.82828  1.000 33.26483 ? 89  THR B C   1 
ATOM   2184 O O   . THR B 2  89  ? 6.83353   4.37470   16.68147  1.000 34.37946 ? 89  THR B O   1 
ATOM   2185 C CB  . THR B 2  89  ? 6.41488   6.53809   19.51661  1.000 39.96866 ? 89  THR B CB  1 
ATOM   2186 O OG1 . THR B 2  89  ? 5.70949   5.77751   20.50634  1.000 31.47485 ? 89  THR B OG1 1 
ATOM   2187 C CG2 . THR B 2  89  ? 6.14103   8.02046   19.72934  1.000 36.69059 ? 89  THR B CG2 1 
ATOM   2188 N N   . THR B 2  90  ? 6.59094   3.86433   18.86971  1.000 33.83455 ? 90  THR B N   1 
ATOM   2189 C CA  . THR B 2  90  ? 7.26502   2.57274   18.75409  1.000 28.06168 ? 90  THR B CA  1 
ATOM   2190 C C   . THR B 2  90  ? 6.61191   1.68057   17.70693  1.000 27.08862 ? 90  THR B C   1 
ATOM   2191 O O   . THR B 2  90  ? 7.30549   0.98564   16.95529  1.000 28.27065 ? 90  THR B O   1 
ATOM   2192 C CB  . THR B 2  90  ? 7.27465   1.86399   20.10834  1.000 32.57507 ? 90  THR B CB  1 
ATOM   2193 O OG1 . THR B 2  90  ? 5.93532   1.78323   20.61323  1.000 26.89745 ? 90  THR B OG1 1 
ATOM   2194 C CG2 . THR B 2  90  ? 8.14281   2.62055   21.10075  1.000 30.46916 ? 90  THR B CG2 1 
ATOM   2195 N N   . LEU B 2  91  ? 5.28081   1.67548   17.64604  1.000 30.04658 ? 91  LEU B N   1 
ATOM   2196 C CA  . LEU B 2  91  ? 4.58180   0.76818   16.74584  1.000 27.70063 ? 91  LEU B CA  1 
ATOM   2197 C C   . LEU B 2  91  ? 4.65282   1.19864   15.28576  1.000 28.79285 ? 91  LEU B C   1 
ATOM   2198 O O   . LEU B 2  91  ? 4.23398   0.43118   14.41292  1.000 30.88587 ? 91  LEU B O   1 
ATOM   2199 C CB  . LEU B 2  91  ? 3.12373   0.62058   17.18425  1.000 29.89117 ? 91  LEU B CB  1 
ATOM   2200 C CG  . LEU B 2  91  ? 2.95671   -0.10619  18.52138  1.000 27.83254 ? 91  LEU B CG  1 
ATOM   2201 C CD1 . LEU B 2  91  ? 1.52835   0.00358   19.02924  1.000 29.40517 ? 91  LEU B CD1 1 
ATOM   2202 C CD2 . LEU B 2  91  ? 3.37915   -1.56561  18.39916  1.000 23.57959 ? 91  LEU B CD2 1 
ATOM   2203 N N   . GLN B 2  92  ? 5.16816   2.39306   14.99816  1.000 30.83428 ? 92  GLN B N   1 
ATOM   2204 C CA  . GLN B 2  92  ? 5.44783   2.80231   13.62835  1.000 34.54156 ? 92  GLN B CA  1 
ATOM   2205 C C   . GLN B 2  92  ? 6.83483   2.38519   13.16247  1.000 36.96688 ? 92  GLN B C   1 
ATOM   2206 O O   . GLN B 2  92  ? 7.10975   2.43847   11.95922  1.000 31.71197 ? 92  GLN B O   1 
ATOM   2207 C CB  . GLN B 2  92  ? 5.31721   4.32211   13.48303  1.000 33.78810 ? 92  GLN B CB  1 
ATOM   2208 C CG  . GLN B 2  92  ? 4.08988   4.91611   14.13467  1.000 46.03681 ? 92  GLN B CG  1 
ATOM   2209 C CD  . GLN B 2  92  ? 2.98203   5.18633   13.13991  1.000 51.60418 ? 92  GLN B CD  1 
ATOM   2210 O OE1 . GLN B 2  92  ? 2.37834   4.25980   12.59959  1.000 57.08805 ? 92  GLN B OE1 1 
ATOM   2211 N NE2 . GLN B 2  92  ? 2.71048   6.46228   12.88860  1.000 59.34710 ? 92  GLN B NE2 1 
ATOM   2212 N N   . ARG B 2  93  ? 7.70446   1.97463   14.08225  1.000 30.75237 ? 93  ARG B N   1 
ATOM   2213 C CA  . ARG B 2  93  ? 9.09318   1.68152   13.75326  1.000 31.85530 ? 93  ARG B CA  1 
ATOM   2214 C C   . ARG B 2  93  ? 9.17998   0.46514   12.83970  1.000 30.57293 ? 93  ARG B C   1 
ATOM   2215 O O   . ARG B 2  93  ? 8.67823   -0.61315  13.17507  1.000 27.85629 ? 93  ARG B O   1 
ATOM   2216 C CB  . ARG B 2  93  ? 9.89056   1.45031   15.03398  1.000 23.94061 ? 93  ARG B CB  1 
ATOM   2217 C CG  . ARG B 2  93  ? 11.32981  1.02100   14.81692  1.000 26.58738 ? 93  ARG B CG  1 
ATOM   2218 C CD  . ARG B 2  93  ? 12.09824  1.06364   16.13036  1.000 28.00581 ? 93  ARG B CD  1 
ATOM   2219 N NE  . ARG B 2  93  ? 13.41747  0.45336   16.02531  1.000 27.25173 ? 93  ARG B NE  1 
ATOM   2220 C CZ  . ARG B 2  93  ? 14.49863  1.08040   15.58335  1.000 27.16960 ? 93  ARG B CZ  1 
ATOM   2221 N NH1 . ARG B 2  93  ? 14.44953  2.33749   15.17436  1.000 29.01685 ? 93  ARG B NH1 1 
ATOM   2222 N NH2 . ARG B 2  93  ? 15.65851  0.43083   15.55401  1.000 28.02182 ? 93  ARG B NH2 1 
ATOM   2223 N N   . ARG B 2  94  ? 9.81231   0.64345   11.68181  1.000 28.75036 ? 94  ARG B N   1 
ATOM   2224 C CA  . ARG B 2  94  ? 10.06996  -0.44679  10.74793  1.000 32.05935 ? 94  ARG B CA  1 
ATOM   2225 C C   . ARG B 2  94  ? 11.50211  -0.31998  10.25780  1.000 32.91895 ? 94  ARG B C   1 
ATOM   2226 O O   . ARG B 2  94  ? 11.85250  0.67525   9.61684   1.000 39.86248 ? 94  ARG B O   1 
ATOM   2227 C CB  . ARG B 2  94  ? 9.09583   -0.42353  9.56382   1.000 32.11308 ? 94  ARG B CB  1 
ATOM   2228 C CG  . ARG B 2  94  ? 7.62924   -0.38424  9.95174   1.000 36.18519 ? 94  ARG B CG  1 
ATOM   2229 C CD  . ARG B 2  94  ? 7.03055   -1.78336  9.99015   1.000 33.45767 ? 94  ARG B CD  1 
ATOM   2230 N NE  . ARG B 2  94  ? 5.58201   -1.76293  10.15995  1.000 40.77172 ? 94  ARG B NE  1 
ATOM   2231 C CZ  . ARG B 2  94  ? 4.95524   -1.37883  11.26429  1.000 42.83170 ? 94  ARG B CZ  1 
ATOM   2232 N NH1 . ARG B 2  94  ? 5.62108   -0.98966  12.33966  1.000 34.84801 ? 94  ARG B NH1 1 
ATOM   2233 N NH2 . ARG B 2  94  ? 3.62543   -1.39004  11.29201  1.000 41.05330 ? 94  ARG B NH2 1 
ATOM   2234 N N   . VAL B 2  95  ? 12.32677  -1.31604  10.56745  1.000 28.52624 ? 95  VAL B N   1 
ATOM   2235 C CA  . VAL B 2  95  ? 13.71376  -1.36687  10.12214  1.000 22.87450 ? 95  VAL B CA  1 
ATOM   2236 C C   . VAL B 2  95  ? 13.89662  -2.65922  9.34181   1.000 30.94188 ? 95  VAL B C   1 
ATOM   2237 O O   . VAL B 2  95  ? 13.69355  -3.75257  9.88600   1.000 23.10049 ? 95  VAL B O   1 
ATOM   2238 C CB  . VAL B 2  95  ? 14.69954  -1.28396  11.29778  1.000 30.07170 ? 95  VAL B CB  1 
ATOM   2239 C CG1 . VAL B 2  95  ? 16.13253  -1.24981  10.78571  1.000 25.99728 ? 95  VAL B CG1 1 
ATOM   2240 C CG2 . VAL B 2  95  ? 14.40305  -0.05860  12.15066  1.000 23.94133 ? 95  VAL B CG2 1 
ATOM   2241 N N   . GLU B 2  96  ? 14.27509  -2.53270  8.07187   1.000 27.08236 ? 96  GLU B N   1 
ATOM   2242 C CA  . GLU B 2  96  ? 14.35422  -3.69256  7.19724   1.000 29.08469 ? 96  GLU B CA  1 
ATOM   2243 C C   . GLU B 2  96  ? 15.56885  -4.54817  7.54854   1.000 27.98598 ? 96  GLU B C   1 
ATOM   2244 O O   . GLU B 2  96  ? 16.63360  -4.01537  7.87560   1.000 31.09282 ? 96  GLU B O   1 
ATOM   2245 C CB  . GLU B 2  96  ? 14.43316  -3.25927  5.73496   1.000 31.27110 ? 96  GLU B CB  1 
ATOM   2246 C CG  . GLU B 2  96  ? 13.14691  -2.65831  5.19681   1.000 43.03023 ? 96  GLU B CG  1 
ATOM   2247 C CD  . GLU B 2  96  ? 13.31849  -2.07570  3.80851   1.000 49.40241 ? 96  GLU B CD  1 
ATOM   2248 O OE1 . GLU B 2  96  ? 14.10673  -2.64115  3.02136   1.000 41.73068 ? 96  GLU B OE1 1 
ATOM   2249 O OE2 . GLU B 2  96  ? 12.66663  -1.05457  3.50446   1.000 51.41943 ? 96  GLU B OE2 1 
ATOM   2250 N N   . PRO B 2  97  ? 15.44448  -5.86939  7.47927   1.000 25.73989 ? 97  PRO B N   1 
ATOM   2251 C CA  . PRO B 2  97  ? 16.56741  -6.74129  7.83024   1.000 23.24798 ? 97  PRO B CA  1 
ATOM   2252 C C   . PRO B 2  97  ? 17.62411  -6.81078  6.73958   1.000 27.71661 ? 97  PRO B C   1 
ATOM   2253 O O   . PRO B 2  97  ? 17.33803  -6.70015  5.54489   1.000 24.21420 ? 97  PRO B O   1 
ATOM   2254 C CB  . PRO B 2  97  ? 15.89895  -8.10710  8.02119   1.000 23.72001 ? 97  PRO B CB  1 
ATOM   2255 C CG  . PRO B 2  97  ? 14.69313  -8.05154  7.14396   1.000 25.72765 ? 97  PRO B CG  1 
ATOM   2256 C CD  . PRO B 2  97  ? 14.21362  -6.62956  7.19837   1.000 22.25761 ? 97  PRO B CD  1 
ATOM   2257 N N   . THR B 2  98  ? 18.86544  -7.00199  7.18115   1.000 24.54864 ? 98  THR B N   1 
ATOM   2258 C CA  . THR B 2  98  ? 19.97932  -7.31655  6.29695   1.000 25.74775 ? 98  THR B CA  1 
ATOM   2259 C C   . THR B 2  98  ? 20.13024  -8.83108  6.23020   1.000 27.79930 ? 98  THR B C   1 
ATOM   2260 O O   . THR B 2  98  ? 20.16251  -9.50041  7.26786   1.000 25.39328 ? 98  THR B O   1 
ATOM   2261 C CB  . THR B 2  98  ? 21.27215  -6.67218  6.80315   1.000 28.02901 ? 98  THR B CB  1 
ATOM   2262 O OG1 . THR B 2  98  ? 21.14215  -5.24531  6.77410   1.000 25.75169 ? 98  THR B OG1 1 
ATOM   2263 C CG2 . THR B 2  98  ? 22.45795  -7.08814  5.94375   1.000 28.27477 ? 98  THR B CG2 1 
ATOM   2264 N N   . VAL B 2  99  ? 20.21282  -9.36972  5.01585   1.000 21.47510 ? 99  VAL B N   1 
ATOM   2265 C CA  . VAL B 2  99  ? 20.19289  -10.81212 4.79139   1.000 24.38373 ? 99  VAL B CA  1 
ATOM   2266 C C   . VAL B 2  99  ? 21.48593  -11.21404 4.09599   1.000 23.59028 ? 99  VAL B C   1 
ATOM   2267 O O   . VAL B 2  99  ? 21.80917  -10.68859 3.02358   1.000 25.71674 ? 99  VAL B O   1 
ATOM   2268 C CB  . VAL B 2  99  ? 18.97241  -11.24172 3.96258   1.000 22.19127 ? 99  VAL B CB  1 
ATOM   2269 C CG1 . VAL B 2  99  ? 18.92265  -12.75733 3.83912   1.000 24.78118 ? 99  VAL B CG1 1 
ATOM   2270 C CG2 . VAL B 2  99  ? 17.69336  -10.70583 4.58316   1.000 22.79785 ? 99  VAL B CG2 1 
ATOM   2271 N N   . THR B 2  100 ? 22.21861  -12.14932 4.70020   1.000 21.56346 ? 100 THR B N   1 
ATOM   2272 C CA  . THR B 2  100 ? 23.46778  -12.64526 4.14112   1.000 32.83865 ? 100 THR B CA  1 
ATOM   2273 C C   . THR B 2  100 ? 23.56448  -14.14742 4.36623   1.000 33.62775 ? 100 THR B C   1 
ATOM   2274 O O   . THR B 2  100 ? 23.05136  -14.67777 5.35506   1.000 32.90366 ? 100 THR B O   1 
ATOM   2275 C CB  . THR B 2  100 ? 24.69535  -11.95477 4.76201   1.000 28.55482 ? 100 THR B CB  1 
ATOM   2276 O OG1 . THR B 2  100 ? 24.62235  -12.03174 6.19071   1.000 32.04976 ? 100 THR B OG1 1 
ATOM   2277 C CG2 . THR B 2  100 ? 24.76411  -10.49506 4.34120   1.000 28.13829 ? 100 THR B CG2 1 
ATOM   2278 N N   . ILE B 2  101 ? 24.23122  -14.82778 3.43629   1.000 28.86603 ? 101 ILE B N   1 
ATOM   2279 C CA  . ILE B 2  101 ? 24.48358  -16.26025 3.52530   1.000 32.56248 ? 101 ILE B CA  1 
ATOM   2280 C C   . ILE B 2  101 ? 25.98757  -16.48888 3.49485   1.000 39.39156 ? 101 ILE B C   1 
ATOM   2281 O O   . ILE B 2  101 ? 26.70082  -15.88382 2.68656   1.000 34.90988 ? 101 ILE B O   1 
ATOM   2282 C CB  . ILE B 2  101 ? 23.79545  -17.04005 2.38603   1.000 32.56718 ? 101 ILE B CB  1 
ATOM   2283 C CG1 . ILE B 2  101 ? 22.28724  -16.79218 2.39532   1.000 28.25797 ? 101 ILE B CG1 1 
ATOM   2284 C CG2 . ILE B 2  101 ? 24.08494  -18.52812 2.50934   1.000 39.38474 ? 101 ILE B CG2 1 
ATOM   2285 C CD1 . ILE B 2  101 ? 21.55930  -17.45725 1.24332   1.000 40.73865 ? 101 ILE B CD1 1 
ATOM   2286 N N   . SER B 2  102 ? 26.46797  -17.36737 4.37725   1.000 35.12044 ? 102 SER B N   1 
ATOM   2287 C CA  . SER B 2  102 ? 27.88004  -17.69477 4.44411   1.000 37.38542 ? 102 SER B CA  1 
ATOM   2288 C C   . SER B 2  102 ? 28.03862  -19.08697 5.03465   1.000 46.70321 ? 102 SER B C   1 
ATOM   2289 O O   . SER B 2  102 ? 27.26707  -19.46174 5.92984   1.000 46.57657 ? 102 SER B O   1 
ATOM   2290 C CB  . SER B 2  102 ? 28.65696  -16.67919 5.28759   1.000 39.13027 ? 102 SER B CB  1 
ATOM   2291 O OG  . SER B 2  102 ? 30.05403  -16.88052 5.16732   1.000 51.75845 ? 102 SER B OG  1 
ATOM   2292 N N   . PRO B 2  103 ? 29.00387  -19.87106 4.56019   1.000 48.80578 ? 103 PRO B N   1 
ATOM   2293 C CA  . PRO B 2  103 ? 29.23715  -21.18832 5.15922   1.000 51.49889 ? 103 PRO B CA  1 
ATOM   2294 C C   . PRO B 2  103 ? 29.86203  -21.06825 6.53982   1.000 54.55723 ? 103 PRO B C   1 
ATOM   2295 O O   . PRO B 2  103 ? 30.57224  -20.10784 6.84903   1.000 50.64037 ? 103 PRO B O   1 
ATOM   2296 C CB  . PRO B 2  103 ? 30.19537  -21.86378 4.17148   1.000 52.02543 ? 103 PRO B CB  1 
ATOM   2297 C CG  . PRO B 2  103 ? 30.88760  -20.73104 3.49130   1.000 51.74385 ? 103 PRO B CG  1 
ATOM   2298 C CD  . PRO B 2  103 ? 29.87077  -19.62982 3.39373   1.000 47.27261 ? 103 PRO B CD  1 
ATOM   2299 N N   . SER B 2  104 ? 29.58538  -22.06441 7.37493   1.000 57.14487 ? 104 SER B N   1 
ATOM   2300 C CA  . SER B 2  104 ? 30.11800  -22.09429 8.73165   1.000 54.77155 ? 104 SER B CA  1 
ATOM   2301 C C   . SER B 2  104 ? 31.39969  -22.91628 8.80048   1.000 51.23979 ? 104 SER B C   1 
ATOM   2302 O O   . SER B 2  104 ? 32.27188  -22.65245 9.62753   1.000 62.77929 ? 104 SER B O   1 
ATOM   2303 C CB  . SER B 2  104 ? 29.08096  -22.65765 9.70396   1.000 58.91943 ? 104 SER B CB  1 
ATOM   2304 O OG  . SER B 2  104 ? 29.66227  -22.91487 10.97011  1.000 68.41645 ? 104 SER B OG  1 
ATOM   2305 N N   . ASN B 2  113 ? 28.39422  -29.97378 7.49565   1.000 77.57281 ? 113 ASN B N   1 
ATOM   2306 C CA  . ASN B 2  113 ? 28.52440  -28.73537 6.73650   1.000 73.95159 ? 113 ASN B CA  1 
ATOM   2307 C C   . ASN B 2  113 ? 27.25871  -27.89494 6.86469   1.000 68.04233 ? 113 ASN B C   1 
ATOM   2308 O O   . ASN B 2  113 ? 26.16667  -28.34207 6.51259   1.000 65.58530 ? 113 ASN B O   1 
ATOM   2309 C CB  . ASN B 2  113 ? 28.82248  -29.03798 5.26871   1.000 76.67460 ? 113 ASN B CB  1 
ATOM   2310 C CG  . ASN B 2  113 ? 30.27246  -29.41100 5.03832   1.000 82.88599 ? 113 ASN B CG  1 
ATOM   2311 O OD1 . ASN B 2  113 ? 31.06598  -29.46695 5.97776   1.000 84.45973 ? 113 ASN B OD1 1 
ATOM   2312 N ND2 . ASN B 2  113 ? 30.62608  -29.67261 3.78610   1.000 86.62417 ? 113 ASN B ND2 1 
ATOM   2313 N N   . LEU B 2  114 ? 27.41258  -26.67253 7.36763   1.000 66.15861 ? 114 LEU B N   1 
ATOM   2314 C CA  . LEU B 2  114 ? 26.28742  -25.81321 7.70808   1.000 63.83048 ? 114 LEU B CA  1 
ATOM   2315 C C   . LEU B 2  114 ? 26.32840  -24.53746 6.88066   1.000 54.16242 ? 114 LEU B C   1 
ATOM   2316 O O   . LEU B 2  114 ? 27.38399  -23.90934 6.74735   1.000 54.89934 ? 114 LEU B O   1 
ATOM   2317 C CB  . LEU B 2  114 ? 26.29478  -25.46999 9.20035   1.000 60.23744 ? 114 LEU B CB  1 
ATOM   2318 C CG  . LEU B 2  114 ? 25.72279  -26.53454 10.13774  1.000 63.41795 ? 114 LEU B CG  1 
ATOM   2319 C CD1 . LEU B 2  114 ? 25.96165  -26.15844 11.59253  1.000 59.14941 ? 114 LEU B CD1 1 
ATOM   2320 C CD2 . LEU B 2  114 ? 24.24047  -26.74074 9.86858   1.000 56.17795 ? 114 LEU B CD2 1 
ATOM   2321 N N   . LEU B 2  115 ? 25.17652  -24.16145 6.33440   1.000 48.80140 ? 115 LEU B N   1 
ATOM   2322 C CA  . LEU B 2  115 ? 24.98924  -22.89571 5.64013   1.000 49.03140 ? 115 LEU B CA  1 
ATOM   2323 C C   . LEU B 2  115 ? 24.16328  -21.97479 6.52646   1.000 49.61520 ? 115 LEU B C   1 
ATOM   2324 O O   . LEU B 2  115 ? 23.06315  -22.34236 6.95083   1.000 44.98329 ? 115 LEU B O   1 
ATOM   2325 C CB  . LEU B 2  115 ? 24.28986  -23.10783 4.29694   1.000 48.54664 ? 115 LEU B CB  1 
ATOM   2326 C CG  . LEU B 2  115 ? 24.62739  -22.13520 3.16844   1.000 54.68222 ? 115 LEU B CG  1 
ATOM   2327 C CD1 . LEU B 2  115 ? 26.13073  -22.06558 2.93794   1.000 48.35717 ? 115 LEU B CD1 1 
ATOM   2328 C CD2 . LEU B 2  115 ? 23.89969  -22.54383 1.90020   1.000 50.48451 ? 115 LEU B CD2 1 
ATOM   2329 N N   . VAL B 2  116 ? 24.68815  -20.78433 6.80102   1.000 44.47344 ? 116 VAL B N   1 
ATOM   2330 C CA  . VAL B 2  116 ? 24.09204  -19.86030 7.76009   1.000 36.34059 ? 116 VAL B CA  1 
ATOM   2331 C C   . VAL B 2  116 ? 23.45933  -18.70342 7.00019   1.000 36.56323 ? 116 VAL B C   1 
ATOM   2332 O O   . VAL B 2  116 ? 24.15816  -17.94451 6.31734   1.000 41.44701 ? 116 VAL B O   1 
ATOM   2333 C CB  . VAL B 2  116 ? 25.13119  -19.34200 8.76606   1.000 36.27793 ? 116 VAL B CB  1 
ATOM   2334 C CG1 . VAL B 2  116 ? 24.44987  -18.54592 9.86882   1.000 33.14304 ? 116 VAL B CG1 1 
ATOM   2335 C CG2 . VAL B 2  116 ? 25.93894  -20.49379 9.34264   1.000 36.10476 ? 116 VAL B CG2 1 
ATOM   2336 N N   . CYS B 2  117 ? 22.14103  -18.56309 7.12159   1.000 34.03100 ? 117 CYS B N   1 
ATOM   2337 C CA  . CYS B 2  117 ? 21.45237  -17.35428 6.68684   1.000 34.78117 ? 117 CYS B CA  1 
ATOM   2338 C C   . CYS B 2  117 ? 21.38525  -16.39329 7.86767   1.000 36.70409 ? 117 CYS B C   1 
ATOM   2339 O O   . CYS B 2  117 ? 20.76288  -16.70034 8.89078   1.000 32.18992 ? 117 CYS B O   1 
ATOM   2340 C CB  . CYS B 2  117 ? 20.05028  -17.66032 6.16129   1.000 28.96752 ? 117 CYS B CB  1 
ATOM   2341 S SG  . CYS B 2  117 ? 19.17715  -16.19301 5.55943   1.000 33.47530 ? 117 CYS B SG  1 
ATOM   2342 N N   . SER B 2  118 ? 22.03068  -15.24010 7.72913   1.000 32.50608 ? 118 SER B N   1 
ATOM   2343 C CA  . SER B 2  118 ? 22.15059  -14.26569 8.80558   1.000 34.60938 ? 118 SER B CA  1 
ATOM   2344 C C   . SER B 2  118 ? 21.20242  -13.10517 8.53360   1.000 33.63905 ? 118 SER B C   1 
ATOM   2345 O O   . SER B 2  118 ? 21.31257  -12.43597 7.49997   1.000 27.81125 ? 118 SER B O   1 
ATOM   2346 C CB  . SER B 2  118 ? 23.59373  -13.77668 8.93538   1.000 34.13006 ? 118 SER B CB  1 
ATOM   2347 O OG  . SER B 2  118 ? 23.65392  -12.53321 9.60880   1.000 38.43080 ? 118 SER B OG  1 
ATOM   2348 N N   . VAL B 2  119 ? 20.27644  -12.87386 9.46024   1.000 25.83815 ? 119 VAL B N   1 
ATOM   2349 C CA  . VAL B 2  119 ? 19.25149  -11.84250 9.33872   1.000 25.83639 ? 119 VAL B CA  1 
ATOM   2350 C C   . VAL B 2  119 ? 19.44257  -10.88502 10.50628  1.000 27.93161 ? 119 VAL B C   1 
ATOM   2351 O O   . VAL B 2  119 ? 19.14799  -11.23671 11.65524  1.000 24.00328 ? 119 VAL B O   1 
ATOM   2352 C CB  . VAL B 2  119 ? 17.83873  -12.44108 9.33883   1.000 26.56393 ? 119 VAL B CB  1 
ATOM   2353 C CG1 . VAL B 2  119 ? 16.82652  -11.41703 8.87416   1.000 24.53828 ? 119 VAL B CG1 1 
ATOM   2354 C CG2 . VAL B 2  119 ? 17.78982  -13.68726 8.46489   1.000 28.44068 ? 119 VAL B CG2 1 
ATOM   2355 N N   . THR B 2  120 ? 19.92546  -9.67549  10.22107  1.000 27.72311 ? 120 THR B N   1 
ATOM   2356 C CA  . THR B 2  120 ? 20.39679  -8.77192  11.26057  1.000 24.07785 ? 120 THR B CA  1 
ATOM   2357 C C   . THR B 2  120 ? 19.71897  -7.41129  11.16424  1.000 25.04377 ? 120 THR B C   1 
ATOM   2358 O O   . THR B 2  120 ? 19.29906  -6.97710  10.08732  1.000 26.26277 ? 120 THR B O   1 
ATOM   2359 C CB  . THR B 2  120 ? 21.92409  -8.58469  11.18531  1.000 25.30597 ? 120 THR B CB  1 
ATOM   2360 O OG1 . THR B 2  120 ? 22.30809  -8.28149  9.83846   1.000 23.34315 ? 120 THR B OG1 1 
ATOM   2361 C CG2 . THR B 2  120 ? 22.63955  -9.84843  11.63241  1.000 24.79353 ? 120 THR B CG2 1 
ATOM   2362 N N   . ASP B 2  121 ? 19.61102  -6.75409  12.32200  1.000 25.38204 ? 121 ASP B N   1 
ATOM   2363 C CA  . ASP B 2  121 ? 19.21599  -5.34821  12.43989  1.000 27.25102 ? 121 ASP B CA  1 
ATOM   2364 C C   . ASP B 2  121 ? 17.81613  -5.09591  11.87423  1.000 24.42798 ? 121 ASP B C   1 
ATOM   2365 O O   . ASP B 2  121 ? 17.61502  -4.26307  10.98769  1.000 33.76087 ? 121 ASP B O   1 
ATOM   2366 C CB  . ASP B 2  121 ? 20.24945  -4.43619  11.76835  1.000 23.91896 ? 121 ASP B CB  1 
ATOM   2367 C CG  . ASP B 2  121 ? 21.57401  -4.41003  12.50815  1.000 31.37289 ? 121 ASP B CG  1 
ATOM   2368 O OD1 . ASP B 2  121 ? 21.56920  -4.51965  13.75291  1.000 29.99151 ? 121 ASP B OD1 1 
ATOM   2369 O OD2 . ASP B 2  121 ? 22.62208  -4.28082  11.84249  1.000 32.34169 ? 121 ASP B OD2 1 
ATOM   2370 N N   . PHE B 2  122 ? 16.83717  -5.81518  12.41779  1.000 24.74102 ? 122 PHE B N   1 
ATOM   2371 C CA  . PHE B 2  122 ? 15.45211  -5.62742  12.01404  1.000 21.90423 ? 122 PHE B CA  1 
ATOM   2372 C C   . PHE B 2  122 ? 14.57616  -5.35926  13.23027  1.000 28.71996 ? 122 PHE B C   1 
ATOM   2373 O O   . PHE B 2  122 ? 14.93614  -5.66598  14.37083  1.000 21.32851 ? 122 PHE B O   1 
ATOM   2374 C CB  . PHE B 2  122 ? 14.91265  -6.83212  11.22054  1.000 25.59050 ? 122 PHE B CB  1 
ATOM   2375 C CG  . PHE B 2  122 ? 14.93574  -8.13363  11.97488  1.000 26.46815 ? 122 PHE B CG  1 
ATOM   2376 C CD1 . PHE B 2  122 ? 13.86436  -8.51214  12.76904  1.000 24.88708 ? 122 PHE B CD1 1 
ATOM   2377 C CD2 . PHE B 2  122 ? 16.01750  -8.99300  11.86500  1.000 23.73649 ? 122 PHE B CD2 1 
ATOM   2378 C CE1 . PHE B 2  122 ? 13.87903  -9.71368  13.45336  1.000 21.00613 ? 122 PHE B CE1 1 
ATOM   2379 C CE2 . PHE B 2  122 ? 16.03778  -10.19674 12.54581  1.000 22.10451 ? 122 PHE B CE2 1 
ATOM   2380 C CZ  . PHE B 2  122 ? 14.96818  -10.55693 13.34206  1.000 20.57779 ? 122 PHE B CZ  1 
ATOM   2381 N N   . TYR B 2  123 ? 13.41071  -4.76423  12.95794  1.000 26.00256 ? 123 TYR B N   1 
ATOM   2382 C CA  . TYR B 2  123 ? 12.39963  -4.44136  13.95376  1.000 27.28194 ? 123 TYR B CA  1 
ATOM   2383 C C   . TYR B 2  123 ? 11.08908  -4.24646  13.21322  1.000 28.54277 ? 123 TYR B C   1 
ATOM   2384 O O   . TYR B 2  123 ? 11.08402  -3.57511  12.17239  1.000 27.39273 ? 123 TYR B O   1 
ATOM   2385 C CB  . TYR B 2  123 ? 12.76412  -3.17853  14.74431  1.000 26.51943 ? 123 TYR B CB  1 
ATOM   2386 C CG  . TYR B 2  123 ? 11.91292  -2.95218  15.97671  1.000 26.98502 ? 123 TYR B CG  1 
ATOM   2387 C CD1 . TYR B 2  123 ? 10.69196  -2.29375  15.89004  1.000 29.41961 ? 123 TYR B CD1 1 
ATOM   2388 C CD2 . TYR B 2  123 ? 12.32919  -3.39779  17.22605  1.000 22.54922 ? 123 TYR B CD2 1 
ATOM   2389 C CE1 . TYR B 2  123 ? 9.90798   -2.08541  17.01020  1.000 25.57167 ? 123 TYR B CE1 1 
ATOM   2390 C CE2 . TYR B 2  123 ? 11.55054  -3.19257  18.35545  1.000 21.55254 ? 123 TYR B CE2 1 
ATOM   2391 C CZ  . TYR B 2  123 ? 10.34085  -2.53587  18.23891  1.000 26.19727 ? 123 TYR B CZ  1 
ATOM   2392 O OH  . TYR B 2  123 ? 9.55849   -2.32571  19.35092  1.000 26.60744 ? 123 TYR B OH  1 
ATOM   2393 N N   . PRO B 2  124 ? 9.96643   -4.79980  13.70259  1.000 30.44013 ? 124 PRO B N   1 
ATOM   2394 C CA  . PRO B 2  124 ? 9.83117   -5.54539  14.95993  1.000 30.76599 ? 124 PRO B CA  1 
ATOM   2395 C C   . PRO B 2  124 ? 10.33119  -6.98598  14.88537  1.000 29.76238 ? 124 PRO B C   1 
ATOM   2396 O O   . PRO B 2  124 ? 10.96589  -7.38319  13.90565  1.000 27.10786 ? 124 PRO B O   1 
ATOM   2397 C CB  . PRO B 2  124 ? 8.31547   -5.52279  15.22581  1.000 34.14146 ? 124 PRO B CB  1 
ATOM   2398 C CG  . PRO B 2  124 ? 7.70253   -4.69211  14.11885  1.000 31.14018 ? 124 PRO B CG  1 
ATOM   2399 C CD  . PRO B 2  124 ? 8.67968   -4.69811  12.99868  1.000 24.25053 ? 124 PRO B CD  1 
ATOM   2400 N N   . ALA B 2  125 ? 10.02180  -7.75872  15.92896  1.000 23.92443 ? 125 ALA B N   1 
ATOM   2401 C CA  . ALA B 2  125 ? 10.54715  -9.11214  16.06343  1.000 31.94653 ? 125 ALA B CA  1 
ATOM   2402 C C   . ALA B 2  125 ? 9.88012   -10.10696 15.12282  1.000 30.09044 ? 125 ALA B C   1 
ATOM   2403 O O   . ALA B 2  125 ? 10.47795  -11.14555 14.82136  1.000 28.65079 ? 125 ALA B O   1 
ATOM   2404 C CB  . ALA B 2  125 ? 10.38829  -9.58769  17.50734  1.000 30.23301 ? 125 ALA B CB  1 
ATOM   2405 N N   . GLN B 2  126 ? 8.66166   -9.82413  14.66758  1.000 30.07018 ? 126 GLN B N   1 
ATOM   2406 C CA  . GLN B 2  126 ? 7.94124   -10.74685 13.79766  1.000 35.21859 ? 126 GLN B CA  1 
ATOM   2407 C C   . GLN B 2  126 ? 8.70974   -10.96446 12.50088  1.000 33.13712 ? 126 GLN B C   1 
ATOM   2408 O O   . GLN B 2  126 ? 8.97558   -10.01236 11.76266  1.000 34.76963 ? 126 GLN B O   1 
ATOM   2409 C CB  . GLN B 2  126 ? 6.54655   -10.19610 13.50580  1.000 38.94851 ? 126 GLN B CB  1 
ATOM   2410 C CG  . GLN B 2  126 ? 5.51803   -11.24417 13.12502  1.000 51.50878 ? 126 GLN B CG  1 
ATOM   2411 C CD  . GLN B 2  126 ? 4.10817   -10.68518 13.10963  1.000 70.16096 ? 126 GLN B CD  1 
ATOM   2412 O OE1 . GLN B 2  126 ? 3.12997   -11.43273 13.11036  1.000 79.26346 ? 126 GLN B OE1 1 
ATOM   2413 N NE2 . GLN B 2  126 ? 3.99781   -9.36091  13.09638  1.000 68.21764 ? 126 GLN B NE2 1 
ATOM   2414 N N   . ILE B 2  127 ? 9.06702   -12.21791 12.22063  1.000 29.73515 ? 127 ILE B N   1 
ATOM   2415 C CA  . ILE B 2  127 ? 9.85456   -12.53743 11.03556  1.000 33.59495 ? 127 ILE B CA  1 
ATOM   2416 C C   . ILE B 2  127 ? 9.68651   -14.01676 10.72487  1.000 30.91153 ? 127 ILE B C   1 
ATOM   2417 O O   . ILE B 2  127 ? 9.50730   -14.84010 11.62620  1.000 35.07001 ? 127 ILE B O   1 
ATOM   2418 C CB  . ILE B 2  127 ? 11.34442  -12.15525 11.23741  1.000 31.34496 ? 127 ILE B CB  1 
ATOM   2419 C CG1 . ILE B 2  127 ? 12.10156  -12.20067 9.90881   1.000 30.34929 ? 127 ILE B CG1 1 
ATOM   2420 C CG2 . ILE B 2  127 ? 12.00506  -13.05260 12.27847  1.000 29.01727 ? 127 ILE B CG2 1 
ATOM   2421 C CD1 . ILE B 2  127 ? 13.31524  -11.30432 9.87656   1.000 26.64719 ? 127 ILE B CD1 1 
ATOM   2422 N N   . LYS B 2  128 ? 9.73794   -14.35112 9.43615   1.000 33.73970 ? 128 LYS B N   1 
ATOM   2423 C CA  . LYS B 2  128 ? 9.71163   -15.73084 8.96921   1.000 34.69171 ? 128 LYS B CA  1 
ATOM   2424 C C   . LYS B 2  128 ? 10.83680  -15.92847 7.96454   1.000 36.76451 ? 128 LYS B C   1 
ATOM   2425 O O   . LYS B 2  128 ? 10.97931  -15.14055 7.02365   1.000 33.30414 ? 128 LYS B O   1 
ATOM   2426 C CB  . LYS B 2  128 ? 8.36129   -16.08372 8.33503   1.000 33.72380 ? 128 LYS B CB  1 
ATOM   2427 N N   . VAL B 2  129 ? 11.63297  -16.97577 8.16883   1.000 36.08970 ? 129 VAL B N   1 
ATOM   2428 C CA  . VAL B 2  129 ? 12.78763  -17.27853 7.33222   1.000 38.91731 ? 129 VAL B CA  1 
ATOM   2429 C C   . VAL B 2  129 ? 12.69080  -18.73625 6.90429   1.000 46.76287 ? 129 VAL B C   1 
ATOM   2430 O O   . VAL B 2  129 ? 12.40451  -19.60906 7.73125   1.000 45.36839 ? 129 VAL B O   1 
ATOM   2431 C CB  . VAL B 2  129 ? 14.11237  -17.02054 8.07811   1.000 43.07243 ? 129 VAL B CB  1 
ATOM   2432 C CG1 . VAL B 2  129 ? 15.30410  -17.36076 7.19503   1.000 30.72375 ? 129 VAL B CG1 1 
ATOM   2433 C CG2 . VAL B 2  129 ? 14.18532  -15.57825 8.56740   1.000 35.87855 ? 129 VAL B CG2 1 
ATOM   2434 N N   . ARG B 2  130 ? 12.92823  -19.00238 5.61941   1.000 44.34844 ? 130 ARG B N   1 
ATOM   2435 C CA  . ARG B 2  130 ? 12.85637  -20.36072 5.09958   1.000 42.69855 ? 130 ARG B CA  1 
ATOM   2436 C C   . ARG B 2  130 ? 13.99843  -20.61646 4.12814   1.000 45.03096 ? 130 ARG B C   1 
ATOM   2437 O O   . ARG B 2  130 ? 14.43685  -19.71905 3.40385   1.000 45.15875 ? 130 ARG B O   1 
ATOM   2438 C CB  . ARG B 2  130 ? 11.51500  -20.63910 4.40910   1.000 48.57677 ? 130 ARG B CB  1 
ATOM   2439 C CG  . ARG B 2  130 ? 10.45599  -21.19869 5.34262   1.000 45.95977 ? 130 ARG B CG  1 
ATOM   2440 C CD  . ARG B 2  130 ? 9.41205   -20.15351 5.67704   1.000 58.54774 ? 130 ARG B CD  1 
ATOM   2441 N NE  . ARG B 2  130 ? 8.79976   -19.61210 4.47021   1.000 67.43573 ? 130 ARG B NE  1 
ATOM   2442 C CZ  . ARG B 2  130 ? 7.83168   -20.21096 3.79006   1.000 68.24814 ? 130 ARG B CZ  1 
ATOM   2443 N NH1 . ARG B 2  130 ? 7.32979   -21.37221 4.17876   1.000 69.57199 ? 130 ARG B NH1 1 
ATOM   2444 N NH2 . ARG B 2  130 ? 7.35505   -19.63044 2.69248   1.000 59.59819 ? 130 ARG B NH2 1 
ATOM   2445 N N   . TRP B 2  131 ? 14.46537  -21.86184 4.11891   1.000 44.65067 ? 131 TRP B N   1 
ATOM   2446 C CA  . TRP B 2  131 ? 15.56400  -22.29780 3.27043   1.000 44.45005 ? 131 TRP B CA  1 
ATOM   2447 C C   . TRP B 2  131 ? 15.02668  -23.05467 2.06249   1.000 57.50866 ? 131 TRP B C   1 
ATOM   2448 O O   . TRP B 2  131 ? 14.07408  -23.83218 2.17629   1.000 54.66193 ? 131 TRP B O   1 
ATOM   2449 C CB  . TRP B 2  131 ? 16.52762  -23.19273 4.05159   1.000 46.86751 ? 131 TRP B CB  1 
ATOM   2450 C CG  . TRP B 2  131 ? 17.66366  -22.46409 4.70288   1.000 50.25829 ? 131 TRP B CG  1 
ATOM   2451 C CD1 . TRP B 2  131 ? 17.82474  -22.22195 6.03625   1.000 47.75062 ? 131 TRP B CD1 1 
ATOM   2452 C CD2 . TRP B 2  131 ? 18.80838  -21.90031 4.05197   1.000 46.02921 ? 131 TRP B CD2 1 
ATOM   2453 N NE1 . TRP B 2  131 ? 18.99466  -21.53634 6.25511   1.000 46.14904 ? 131 TRP B NE1 1 
ATOM   2454 C CE2 . TRP B 2  131 ? 19.61715  -21.32635 5.05287   1.000 47.57888 ? 131 TRP B CE2 1 
ATOM   2455 C CE3 . TRP B 2  131 ? 19.22585  -21.82144 2.71996   1.000 44.12948 ? 131 TRP B CE3 1 
ATOM   2456 C CZ2 . TRP B 2  131 ? 20.81955  -20.68470 4.76390   1.000 43.08542 ? 131 TRP B CZ2 1 
ATOM   2457 C CZ3 . TRP B 2  131 ? 20.41853  -21.18152 2.43503   1.000 43.75917 ? 131 TRP B CZ3 1 
ATOM   2458 C CH2 . TRP B 2  131 ? 21.20097  -20.62106 3.45227   1.000 49.91553 ? 131 TRP B CH2 1 
ATOM   2459 N N   . PHE B 2  132 ? 15.64697  -22.82541 0.90649   1.000 53.60806 ? 132 PHE B N   1 
ATOM   2460 C CA  . PHE B 2  132 ? 15.29644  -23.50939 -0.33029  1.000 56.43333 ? 132 PHE B CA  1 
ATOM   2461 C C   . PHE B 2  132 ? 16.56188  -24.03839 -0.98792  1.000 55.78812 ? 132 PHE B C   1 
ATOM   2462 O O   . PHE B 2  132 ? 17.60365  -23.37633 -0.96735  1.000 54.00284 ? 132 PHE B O   1 
ATOM   2463 C CB  . PHE B 2  132 ? 14.55871  -22.57826 -1.30495  1.000 51.44601 ? 132 PHE B CB  1 
ATOM   2464 C CG  . PHE B 2  132 ? 13.19135  -22.16520 -0.83892  1.000 54.67212 ? 132 PHE B CG  1 
ATOM   2465 C CD1 . PHE B 2  132 ? 13.03683  -21.13168 0.07060   1.000 56.00996 ? 132 PHE B CD1 1 
ATOM   2466 C CD2 . PHE B 2  132 ? 12.05922  -22.80394 -1.31819  1.000 57.50598 ? 132 PHE B CD2 1 
ATOM   2467 C CE1 . PHE B 2  132 ? 11.77957  -20.74684 0.49883   1.000 52.84587 ? 132 PHE B CE1 1 
ATOM   2468 C CE2 . PHE B 2  132 ? 10.79885  -22.42376 -0.89369  1.000 56.64339 ? 132 PHE B CE2 1 
ATOM   2469 C CZ  . PHE B 2  132 ? 10.65925  -21.39370 0.01581   1.000 54.61710 ? 132 PHE B CZ  1 
ATOM   2470 N N   . ARG B 2  133 ? 16.46862  -25.23340 -1.56914  1.000 57.59282 ? 133 ARG B N   1 
ATOM   2471 C CA  . ARG B 2  133 ? 17.57583  -25.84085 -2.29913  1.000 60.11834 ? 133 ARG B CA  1 
ATOM   2472 C C   . ARG B 2  133 ? 17.05921  -26.33161 -3.64184  1.000 66.42006 ? 133 ARG B C   1 
ATOM   2473 O O   . ARG B 2  133 ? 16.22879  -27.24543 -3.69067  1.000 70.98191 ? 133 ARG B O   1 
ATOM   2474 C CB  . ARG B 2  133 ? 18.20393  -26.99346 -1.51048  1.000 58.77604 ? 133 ARG B CB  1 
ATOM   2475 C CG  . ARG B 2  133 ? 19.47371  -27.54399 -2.14185  1.000 65.60382 ? 133 ARG B CG  1 
ATOM   2476 C CD  . ARG B 2  133 ? 19.76598  -28.96033 -1.67542  1.000 71.67433 ? 133 ARG B CD  1 
ATOM   2477 N NE  . ARG B 2  133 ? 18.64515  -29.85882 -1.92344  1.000 82.73604 ? 133 ARG B NE  1 
ATOM   2478 C CZ  . ARG B 2  133 ? 18.76615  -31.10275 -2.36634  1.000 84.24399 ? 133 ARG B CZ  1 
ATOM   2479 N NH1 . ARG B 2  133 ? 19.95055  -31.63135 -2.62753  1.000 78.43338 ? 133 ARG B NH1 1 
ATOM   2480 N NH2 . ARG B 2  133 ? 17.67118  -31.83434 -2.55300  1.000 87.28781 ? 133 ARG B NH2 1 
ATOM   2481 N N   . ASN B 2  134 ? 17.55378  -25.72613 -4.72374  1.000 62.30170 ? 134 ASN B N   1 
ATOM   2482 C CA  . ASN B 2  134 ? 17.11345  -26.04609 -6.08267  1.000 58.14154 ? 134 ASN B CA  1 
ATOM   2483 C C   . ASN B 2  134 ? 15.59925  -25.90601 -6.21622  1.000 61.05122 ? 134 ASN B C   1 
ATOM   2484 O O   . ASN B 2  134 ? 14.92994  -26.71690 -6.85985  1.000 63.72022 ? 134 ASN B O   1 
ATOM   2485 C CB  . ASN B 2  134 ? 17.57523  -27.44407 -6.50015  1.000 54.62335 ? 134 ASN B CB  1 
ATOM   2486 C CG  . ASN B 2  134 ? 19.07971  -27.60933 -6.41579  1.000 59.02023 ? 134 ASN B CG  1 
ATOM   2487 O OD1 . ASN B 2  134 ? 19.83340  -26.83230 -7.00131  1.000 64.68759 ? 134 ASN B OD1 1 
ATOM   2488 N ND2 . ASN B 2  134 ? 19.52503  -28.62772 -5.68850  1.000 61.79824 ? 134 ASN B ND2 1 
ATOM   2489 N N   . GLY B 2  135 ? 15.05329  -24.86198 -5.59253  1.000 60.86469 ? 135 GLY B N   1 
ATOM   2490 C CA  . GLY B 2  135 ? 13.63460  -24.58603 -5.64697  1.000 62.25889 ? 135 GLY B CA  1 
ATOM   2491 C C   . GLY B 2  135 ? 12.78325  -25.33766 -4.64762  1.000 62.18973 ? 135 GLY B C   1 
ATOM   2492 O O   . GLY B 2  135 ? 11.60351  -24.99765 -4.48833  1.000 60.24394 ? 135 GLY B O   1 
ATOM   2493 N N   . GLN B 2  136 ? 13.32983  -26.34105 -3.96731  1.000 60.67836 ? 136 GLN B N   1 
ATOM   2494 C CA  . GLN B 2  136 ? 12.57597  -27.14772 -3.01651  1.000 65.52914 ? 136 GLN B CA  1 
ATOM   2495 C C   . GLN B 2  136 ? 12.83428  -26.65352 -1.59922  1.000 61.52558 ? 136 GLN B C   1 
ATOM   2496 O O   . GLN B 2  136 ? 13.99061  -26.51531 -1.18585  1.000 62.01253 ? 136 GLN B O   1 
ATOM   2497 C CB  . GLN B 2  136 ? 12.95322  -28.62522 -3.13759  1.000 63.86499 ? 136 GLN B CB  1 
ATOM   2498 N N   . GLU B 2  137 ? 11.75819  -26.39348 -0.85970  1.000 57.89398 ? 137 GLU B N   1 
ATOM   2499 C CA  . GLU B 2  137 ? 11.89008  -25.93676 0.51721   1.000 61.05755 ? 137 GLU B CA  1 
ATOM   2500 C C   . GLU B 2  137 ? 12.46768  -27.04337 1.39036   1.000 64.80594 ? 137 GLU B C   1 
ATOM   2501 O O   . GLU B 2  137 ? 11.95890  -28.16831 1.40572   1.000 69.89893 ? 137 GLU B O   1 
ATOM   2502 C CB  . GLU B 2  137 ? 10.53684  -25.48761 1.06603   1.000 57.13884 ? 137 GLU B CB  1 
ATOM   2503 C CG  . GLU B 2  137 ? 10.61299  -24.91796 2.47574   1.000 61.91515 ? 137 GLU B CG  1 
ATOM   2504 C CD  . GLU B 2  137 ? 9.34782   -24.19247 2.88958   1.000 63.67595 ? 137 GLU B CD  1 
ATOM   2505 O OE1 . GLU B 2  137 ? 8.60018   -23.73838 1.99838   1.000 64.57502 ? 137 GLU B OE1 1 
ATOM   2506 O OE2 . GLU B 2  137 ? 9.10396   -24.07250 4.10906   1.000 67.59414 ? 137 GLU B OE2 1 
ATOM   2507 N N   . GLU B 2  138 ? 13.53396  -26.72119 2.11774   1.000 58.47807 ? 138 GLU B N   1 
ATOM   2508 C CA  . GLU B 2  138 ? 14.16784  -27.66128 3.03537   1.000 64.74307 ? 138 GLU B CA  1 
ATOM   2509 C C   . GLU B 2  138 ? 13.53762  -27.49225 4.41302   1.000 69.13088 ? 138 GLU B C   1 
ATOM   2510 O O   . GLU B 2  138 ? 13.69844  -26.44791 5.05293   1.000 67.36748 ? 138 GLU B O   1 
ATOM   2511 C CB  . GLU B 2  138 ? 15.67564  -27.43070 3.08796   1.000 61.92664 ? 138 GLU B CB  1 
ATOM   2512 C CG  . GLU B 2  138 ? 16.36780  -27.52947 1.73848   1.000 67.91996 ? 138 GLU B CG  1 
ATOM   2513 C CD  . GLU B 2  138 ? 16.83669  -28.93684 1.42604   1.000 71.56195 ? 138 GLU B CD  1 
ATOM   2514 O OE1 . GLU B 2  138 ? 17.89051  -29.34482 1.95830   1.000 64.37229 ? 138 GLU B OE1 1 
ATOM   2515 O OE2 . GLU B 2  138 ? 16.15174  -29.63501 0.64871   1.000 75.68699 ? 138 GLU B OE2 1 
ATOM   2516 N N   . THR B 2  139 ? 12.81705  -28.51661 4.86852   1.000 67.70141 ? 139 THR B N   1 
ATOM   2517 C CA  . THR B 2  139 ? 12.17934  -28.47085 6.17881   1.000 70.06377 ? 139 THR B CA  1 
ATOM   2518 C C   . THR B 2  139 ? 13.07432  -29.05249 7.26959   1.000 72.23359 ? 139 THR B C   1 
ATOM   2519 O O   . THR B 2  139 ? 13.21037  -28.46038 8.34495   1.000 69.40108 ? 139 THR B O   1 
ATOM   2520 C CB  . THR B 2  139 ? 10.83552  -29.20913 6.14201   1.000 69.75021 ? 139 THR B CB  1 
ATOM   2521 O OG1 . THR B 2  139 ? 10.38505  -29.45386 7.48037   1.000 82.78941 ? 139 THR B OG1 1 
ATOM   2522 C CG2 . THR B 2  139 ? 10.95971  -30.53293 5.39547   1.000 71.81831 ? 139 THR B CG2 1 
ATOM   2523 N N   . ALA B 2  140 ? 13.69001  -30.20063 7.00871   1.000 69.14164 ? 140 ALA B N   1 
ATOM   2524 C CA  . ALA B 2  140 ? 14.57417  -30.83960 7.96889   1.000 66.35880 ? 140 ALA B CA  1 
ATOM   2525 C C   . ALA B 2  140 ? 16.01620  -30.40666 7.73137   1.000 68.61880 ? 140 ALA B C   1 
ATOM   2526 O O   . ALA B 2  140 ? 16.38551  -29.94908 6.64733   1.000 71.83003 ? 140 ALA B O   1 
ATOM   2527 C CB  . ALA B 2  140 ? 14.45694  -32.36152 7.88549   1.000 73.81104 ? 140 ALA B CB  1 
ATOM   2528 N N   . GLY B 2  141 ? 16.83634  -30.56511 8.76701   1.000 67.21000 ? 141 GLY B N   1 
ATOM   2529 C CA  . GLY B 2  141 ? 18.18200  -30.03869 8.74870   1.000 63.57515 ? 141 GLY B CA  1 
ATOM   2530 C C   . GLY B 2  141 ? 18.27483  -28.54883 8.98321   1.000 58.22655 ? 141 GLY B C   1 
ATOM   2531 O O   . GLY B 2  141 ? 19.38950  -28.01194 9.01852   1.000 61.41464 ? 141 GLY B O   1 
ATOM   2532 N N   . VAL B 2  142 ? 17.14517  -27.86589 9.14313   1.000 54.64098 ? 142 VAL B N   1 
ATOM   2533 C CA  . VAL B 2  142 ? 17.12194  -26.43022 9.39298   1.000 54.16219 ? 142 VAL B CA  1 
ATOM   2534 C C   . VAL B 2  142 ? 17.12148  -26.22324 10.90352  1.000 60.02680 ? 142 VAL B C   1 
ATOM   2535 O O   . VAL B 2  142 ? 16.13135  -26.50966 11.58224  1.000 54.64092 ? 142 VAL B O   1 
ATOM   2536 C CB  . VAL B 2  142 ? 15.90868  -25.76343 8.73293   1.000 54.46346 ? 142 VAL B CB  1 
ATOM   2537 C CG1 . VAL B 2  142 ? 15.65546  -24.38545 9.33273   1.000 47.84154 ? 142 VAL B CG1 1 
ATOM   2538 C CG2 . VAL B 2  142 ? 16.11459  -25.66354 7.22915   1.000 56.11041 ? 142 VAL B CG2 1 
ATOM   2539 N N   . VAL B 2  143 ? 18.24306  -25.74470 11.43336  1.000 59.10199 ? 143 VAL B N   1 
ATOM   2540 C CA  . VAL B 2  143 ? 18.38192  -25.41710 12.84665  1.000 53.72275 ? 143 VAL B CA  1 
ATOM   2541 C C   . VAL B 2  143 ? 18.52160  -23.90693 12.96365  1.000 55.17585 ? 143 VAL B C   1 
ATOM   2542 O O   . VAL B 2  143 ? 19.33865  -23.29633 12.26377  1.000 52.19064 ? 143 VAL B O   1 
ATOM   2543 C CB  . VAL B 2  143 ? 19.58236  -26.14039 13.48168  1.000 55.30368 ? 143 VAL B CB  1 
ATOM   2544 C CG1 . VAL B 2  143 ? 19.19583  -27.55805 13.87390  1.000 60.18677 ? 143 VAL B CG1 1 
ATOM   2545 C CG2 . VAL B 2  143 ? 20.76416  -26.15533 12.52406  1.000 60.13547 ? 143 VAL B CG2 1 
ATOM   2546 N N   . SER B 2  144 ? 17.72188  -23.30477 13.83782  1.000 51.78211 ? 144 SER B N   1 
ATOM   2547 C CA  . SER B 2  144 ? 17.66647  -21.85781 13.97509  1.000 47.26802 ? 144 SER B CA  1 
ATOM   2548 C C   . SER B 2  144 ? 18.04476  -21.44419 15.38934  1.000 50.39232 ? 144 SER B C   1 
ATOM   2549 O O   . SER B 2  144 ? 17.66632  -22.10173 16.36402  1.000 54.70152 ? 144 SER B O   1 
ATOM   2550 C CB  . SER B 2  144 ? 16.27077  -21.32644 13.63549  1.000 49.68500 ? 144 SER B CB  1 
ATOM   2551 O OG  . SER B 2  144 ? 16.16413  -19.94731 13.94057  1.000 51.36835 ? 144 SER B OG  1 
ATOM   2552 N N   . THR B 2  145 ? 18.79939  -20.35374 15.49185  1.000 48.38901 ? 145 THR B N   1 
ATOM   2553 C CA  . THR B 2  145 ? 19.07694  -19.75499 16.78144  1.000 38.86457 ? 145 THR B CA  1 
ATOM   2554 C C   . THR B 2  145 ? 17.80772  -19.10861 17.32657  1.000 39.22490 ? 145 THR B C   1 
ATOM   2555 O O   . THR B 2  145 ? 16.85512  -18.86692 16.58157  1.000 40.38330 ? 145 THR B O   1 
ATOM   2556 C CB  . THR B 2  145 ? 20.17888  -18.70407 16.66039  1.000 42.19593 ? 145 THR B CB  1 
ATOM   2557 O OG1 . THR B 2  145 ? 19.69672  -17.59191 15.89464  1.000 39.13003 ? 145 THR B OG1 1 
ATOM   2558 C CG2 . THR B 2  145 ? 21.40910  -19.29064 15.98420  1.000 43.15600 ? 145 THR B CG2 1 
ATOM   2559 N N   . PRO B 2  146 ? 17.76089  -18.82919 18.62592  1.000 38.46647 ? 146 PRO B N   1 
ATOM   2560 C CA  . PRO B 2  146 ? 16.66415  -18.01429 19.15201  1.000 33.47337 ? 146 PRO B CA  1 
ATOM   2561 C C   . PRO B 2  146 ? 16.73731  -16.59850 18.60325  1.000 32.61820 ? 146 PRO B C   1 
ATOM   2562 O O   . PRO B 2  146 ? 17.76747  -16.14643 18.09860  1.000 39.73083 ? 146 PRO B O   1 
ATOM   2563 C CB  . PRO B 2  146 ? 16.89125  -18.03422 20.66897  1.000 33.38807 ? 146 PRO B CB  1 
ATOM   2564 C CG  . PRO B 2  146 ? 17.77806  -19.21119 20.91314  1.000 42.29714 ? 146 PRO B CG  1 
ATOM   2565 C CD  . PRO B 2  146 ? 18.64335  -19.31784 19.69939  1.000 37.18440 ? 146 PRO B CD  1 
ATOM   2566 N N   . LEU B 2  147 ? 15.61186  -15.89945 18.69638  1.000 31.93592 ? 147 LEU B N   1 
ATOM   2567 C CA  . LEU B 2  147 ? 15.59412  -14.48137 18.36908  1.000 34.82303 ? 147 LEU B CA  1 
ATOM   2568 C C   . LEU B 2  147 ? 16.49764  -13.72395 19.33456  1.000 33.54812 ? 147 LEU B C   1 
ATOM   2569 O O   . LEU B 2  147 ? 16.31335  -13.79153 20.55366  1.000 33.10942 ? 147 LEU B O   1 
ATOM   2570 C CB  . LEU B 2  147 ? 14.16592  -13.94728 18.43167  1.000 28.11483 ? 147 LEU B CB  1 
ATOM   2571 C CG  . LEU B 2  147 ? 13.98667  -12.46552 18.11048  1.000 36.74128 ? 147 LEU B CG  1 
ATOM   2572 C CD1 . LEU B 2  147 ? 13.91014  -12.24481 16.60383  1.000 28.24387 ? 147 LEU B CD1 1 
ATOM   2573 C CD2 . LEU B 2  147 ? 12.74534  -11.93674 18.80175  1.000 34.15498 ? 147 LEU B CD2 1 
ATOM   2574 N N   . ILE B 2  148 ? 17.48056  -13.01305 18.79119  1.000 29.27205 ? 148 ILE B N   1 
ATOM   2575 C CA  . ILE B 2  148 ? 18.50161  -12.34301 19.58780  1.000 27.63217 ? 148 ILE B CA  1 
ATOM   2576 C C   . ILE B 2  148 ? 18.13946  -10.87008 19.70917  1.000 28.60734 ? 148 ILE B C   1 
ATOM   2577 O O   . ILE B 2  148 ? 18.04938  -10.15656 18.70235  1.000 24.43874 ? 148 ILE B O   1 
ATOM   2578 C CB  . ILE B 2  148 ? 19.89832  -12.51992 18.97272  1.000 30.98930 ? 148 ILE B CB  1 
ATOM   2579 C CG1 . ILE B 2  148 ? 20.28369  -14.00069 18.95276  1.000 28.72851 ? 148 ILE B CG1 1 
ATOM   2580 C CG2 . ILE B 2  148 ? 20.92681  -11.70685 19.74491  1.000 24.30481 ? 148 ILE B CG2 1 
ATOM   2581 C CD1 . ILE B 2  148 ? 21.33049  -14.34581 17.92253  1.000 30.62384 ? 148 ILE B CD1 1 
ATOM   2582 N N   . ARG B 2  149 ? 17.93945  -10.41536 20.94284  1.000 24.29065 ? 149 ARG B N   1 
ATOM   2583 C CA  . ARG B 2  149 ? 17.64703  -9.01703  21.22557  1.000 24.22666 ? 149 ARG B CA  1 
ATOM   2584 C C   . ARG B 2  149 ? 18.96066  -8.26367  21.39907  1.000 26.66174 ? 149 ARG B C   1 
ATOM   2585 O O   . ARG B 2  149 ? 19.76699  -8.60727  22.27005  1.000 22.82030 ? 149 ARG B O   1 
ATOM   2586 C CB  . ARG B 2  149 ? 16.78038  -8.89790  22.47824  1.000 22.92341 ? 149 ARG B CB  1 
ATOM   2587 C CG  . ARG B 2  149 ? 16.31486  -7.48924  22.79730  1.000 27.60957 ? 149 ARG B CG  1 
ATOM   2588 C CD  . ARG B 2  149 ? 15.50012  -7.47038  24.08487  1.000 32.82613 ? 149 ARG B CD  1 
ATOM   2589 N NE  . ARG B 2  149 ? 14.29264  -8.28079  23.97710  1.000 29.70850 ? 149 ARG B NE  1 
ATOM   2590 C CZ  . ARG B 2  149 ? 13.14687  -7.85187  23.46574  1.000 27.84906 ? 149 ARG B CZ  1 
ATOM   2591 N NH1 . ARG B 2  149 ? 13.00994  -6.61434  23.01849  1.000 26.26257 ? 149 ARG B NH1 1 
ATOM   2592 N NH2 . ARG B 2  149 ? 12.11230  -8.68527  23.40177  1.000 29.24140 ? 149 ARG B NH2 1 
ATOM   2593 N N   . ASN B 2  150 ? 19.17970  -7.24447  20.56552  1.000 27.09417 ? 150 ASN B N   1 
ATOM   2594 C CA  . ASN B 2  150 ? 20.41504  -6.47426  20.63920  1.000 28.40601 ? 150 ASN B CA  1 
ATOM   2595 C C   . ASN B 2  150 ? 20.36860  -5.38633  21.70357  1.000 29.73299 ? 150 ASN B C   1 
ATOM   2596 O O   . ASN B 2  150 ? 21.42707  -4.90361  22.12171  1.000 29.30488 ? 150 ASN B O   1 
ATOM   2597 C CB  . ASN B 2  150 ? 20.73303  -5.84590  19.27937  1.000 22.74416 ? 150 ASN B CB  1 
ATOM   2598 C CG  . ASN B 2  150 ? 21.06443  -6.87956  18.22050  1.000 24.73609 ? 150 ASN B CG  1 
ATOM   2599 O OD1 . ASN B 2  150 ? 21.73103  -7.87768  18.49607  1.000 25.21539 ? 150 ASN B OD1 1 
ATOM   2600 N ND2 . ASN B 2  150 ? 20.60527  -6.64031  16.99684  1.000 21.01332 ? 150 ASN B ND2 1 
ATOM   2601 N N   . GLY B 2  151 ? 19.17599  -4.99279  22.15081  1.000 26.35998 ? 151 GLY B N   1 
ATOM   2602 C CA  . GLY B 2  151 ? 19.02979  -3.96192  23.15449  1.000 19.97442 ? 151 GLY B CA  1 
ATOM   2603 C C   . GLY B 2  151 ? 18.94585  -2.55003  22.61634  1.000 27.10124 ? 151 GLY B C   1 
ATOM   2604 O O   . GLY B 2  151 ? 18.63050  -1.63075  23.38237  1.000 19.53104 ? 151 GLY B O   1 
ATOM   2605 N N   . ASP B 2  152 ? 19.21941  -2.34436  21.32801  1.000 21.85967 ? 152 ASP B N   1 
ATOM   2606 C CA  . ASP B 2  152 ? 19.13166  -1.03217  20.69996  1.000 23.21328 ? 152 ASP B CA  1 
ATOM   2607 C C   . ASP B 2  152 ? 17.90426  -0.91846  19.79961  1.000 28.93400 ? 152 ASP B C   1 
ATOM   2608 O O   . ASP B 2  152 ? 17.92954  -0.20401  18.79396  1.000 26.08443 ? 152 ASP B O   1 
ATOM   2609 C CB  . ASP B 2  152 ? 20.40348  -0.73462  19.90734  1.000 24.60572 ? 152 ASP B CB  1 
ATOM   2610 C CG  . ASP B 2  152 ? 20.67955  -1.77334  18.83494  1.000 27.73285 ? 152 ASP B CG  1 
ATOM   2611 O OD1 . ASP B 2  152 ? 19.90607  -2.74985  18.73141  1.000 27.82629 ? 152 ASP B OD1 1 
ATOM   2612 O OD2 . ASP B 2  152 ? 21.67073  -1.61233  18.09208  1.000 30.87681 ? 152 ASP B OD2 1 
ATOM   2613 N N   . TRP B 2  153 ? 16.83118  -1.63062  20.15225  1.000 26.06720 ? 153 TRP B N   1 
ATOM   2614 C CA  . TRP B 2  153 ? 15.59862  -1.68834  19.36279  1.000 27.46507 ? 153 TRP B CA  1 
ATOM   2615 C C   . TRP B 2  153 ? 15.82944  -2.32192  17.99156  1.000 26.49762 ? 153 TRP B C   1 
ATOM   2616 O O   . TRP B 2  153 ? 15.18683  -1.95062  17.00621  1.000 23.57919 ? 153 TRP B O   1 
ATOM   2617 C CB  . TRP B 2  153 ? 14.95287  -0.30518  19.22087  1.000 22.00228 ? 153 TRP B CB  1 
ATOM   2618 C CG  . TRP B 2  153 ? 14.50215  0.27819   20.52775  1.000 26.75414 ? 153 TRP B CG  1 
ATOM   2619 C CD1 . TRP B 2  153 ? 15.28273  0.88775   21.46707  1.000 29.21225 ? 153 TRP B CD1 1 
ATOM   2620 C CD2 . TRP B 2  153 ? 13.16433  0.30217   21.04169  1.000 30.80337 ? 153 TRP B CD2 1 
ATOM   2621 N NE1 . TRP B 2  153 ? 14.51405  1.29149   22.53226  1.000 28.76978 ? 153 TRP B NE1 1 
ATOM   2622 C CE2 . TRP B 2  153 ? 13.20982  0.94485   22.29484  1.000 30.65532 ? 153 TRP B CE2 1 
ATOM   2623 C CE3 . TRP B 2  153 ? 11.93249  -0.15582  20.56255  1.000 27.70873 ? 153 TRP B CE3 1 
ATOM   2624 C CZ2 . TRP B 2  153 ? 12.07177  1.13862   23.07631  1.000 31.96499 ? 153 TRP B CZ2 1 
ATOM   2625 C CZ3 . TRP B 2  153 ? 10.80466  0.03856   21.33856  1.000 28.18643 ? 153 TRP B CZ3 1 
ATOM   2626 C CH2 . TRP B 2  153 ? 10.88202  0.67946   22.58205  1.000 29.22158 ? 153 TRP B CH2 1 
ATOM   2627 N N   . THR B 2  154 ? 16.75535  -3.27759  17.91693  1.000 21.94511 ? 154 THR B N   1 
ATOM   2628 C CA  . THR B 2  154 ? 16.92235  -4.11949  16.74017  1.000 22.63740 ? 154 THR B CA  1 
ATOM   2629 C C   . THR B 2  154 ? 17.11325  -5.56042  17.19074  1.000 21.81646 ? 154 THR B C   1 
ATOM   2630 O O   . THR B 2  154 ? 17.51772  -5.83076  18.32447  1.000 25.30112 ? 154 THR B O   1 
ATOM   2631 C CB  . THR B 2  154 ? 18.11393  -3.69596  15.85898  1.000 25.09053 ? 154 THR B CB  1 
ATOM   2632 O OG1 . THR B 2  154 ? 19.34417  -4.04147  16.50813  1.000 22.24625 ? 154 THR B OG1 1 
ATOM   2633 C CG2 . THR B 2  154 ? 18.08967  -2.20019  15.56519  1.000 27.30565 ? 154 THR B CG2 1 
ATOM   2634 N N   . PHE B 2  155 ? 16.81490  -6.48423  16.28299  1.000 22.75279 ? 155 PHE B N   1 
ATOM   2635 C CA  . PHE B 2  155 ? 16.96076  -7.91396  16.50801  1.000 20.40365 ? 155 PHE B CA  1 
ATOM   2636 C C   . PHE B 2  155 ? 17.88630  -8.51197  15.45693  1.000 24.32728 ? 155 PHE B C   1 
ATOM   2637 O O   . PHE B 2  155 ? 18.21553  -7.88238  14.44838  1.000 22.08636 ? 155 PHE B O   1 
ATOM   2638 C CB  . PHE B 2  155 ? 15.60513  -8.63320  16.45100  1.000 24.60365 ? 155 PHE B CB  1 
ATOM   2639 C CG  . PHE B 2  155 ? 14.68347  -8.30075  17.58599  1.000 26.27529 ? 155 PHE B CG  1 
ATOM   2640 C CD1 . PHE B 2  155 ? 14.83446  -8.91058  18.82053  1.000 26.89597 ? 155 PHE B CD1 1 
ATOM   2641 C CD2 . PHE B 2  155 ? 13.64793  -7.39631  17.41093  1.000 26.74771 ? 155 PHE B CD2 1 
ATOM   2642 C CE1 . PHE B 2  155 ? 13.97774  -8.61323  19.86690  1.000 29.82927 ? 155 PHE B CE1 1 
ATOM   2643 C CE2 . PHE B 2  155 ? 12.78779  -7.09515  18.45204  1.000 30.97687 ? 155 PHE B CE2 1 
ATOM   2644 C CZ  . PHE B 2  155 ? 12.95464  -7.70366  19.68246  1.000 28.13261 ? 155 PHE B CZ  1 
ATOM   2645 N N   . GLN B 2  156 ? 18.29858  -9.75280  15.70459  1.000 25.34549 ? 156 GLN B N   1 
ATOM   2646 C CA  . GLN B 2  156 ? 18.95460  -10.55720 14.68667  1.000 25.66090 ? 156 GLN B CA  1 
ATOM   2647 C C   . GLN B 2  156 ? 18.63515  -12.02092 14.94747  1.000 28.59179 ? 156 GLN B C   1 
ATOM   2648 O O   . GLN B 2  156 ? 18.25376  -12.40605 16.05613  1.000 27.91868 ? 156 GLN B O   1 
ATOM   2649 C CB  . GLN B 2  156 ? 20.47309  -10.32947 14.64802  1.000 26.85461 ? 156 GLN B CB  1 
ATOM   2650 C CG  . GLN B 2  156 ? 21.19575  -10.52877 15.96805  1.000 24.40148 ? 156 GLN B CG  1 
ATOM   2651 C CD  . GLN B 2  156 ? 22.70381  -10.39245 15.82206  1.000 28.90480 ? 156 GLN B CD  1 
ATOM   2652 O OE1 . GLN B 2  156 ? 23.33369  -11.12675 15.05945  1.000 25.25539 ? 156 GLN B OE1 1 
ATOM   2653 N NE2 . GLN B 2  156 ? 23.28781  -9.44519  16.54818  1.000 22.68592 ? 156 GLN B NE2 1 
ATOM   2654 N N   . ILE B 2  157 ? 18.78061  -12.83263 13.90411  1.000 27.64290 ? 157 ILE B N   1 
ATOM   2655 C CA  . ILE B 2  157 ? 18.53083  -14.26639 13.99905  1.000 27.22148 ? 157 ILE B CA  1 
ATOM   2656 C C   . ILE B 2  157 ? 19.37890  -14.97078 12.95020  1.000 29.55905 ? 157 ILE B C   1 
ATOM   2657 O O   . ILE B 2  157 ? 19.61185  -14.44091 11.85950  1.000 34.47048 ? 157 ILE B O   1 
ATOM   2658 C CB  . ILE B 2  157 ? 17.02770  -14.59313 13.83874  1.000 28.97177 ? 157 ILE B CB  1 
ATOM   2659 C CG1 . ILE B 2  157 ? 16.75509  -16.06372 14.16807  1.000 36.29429 ? 157 ILE B CG1 1 
ATOM   2660 C CG2 . ILE B 2  157 ? 16.53266  -14.24422 12.44086  1.000 29.27806 ? 157 ILE B CG2 1 
ATOM   2661 C CD1 . ILE B 2  157 ? 15.32429  -16.34465 14.57981  1.000 32.62034 ? 157 ILE B CD1 1 
ATOM   2662 N N   . LEU B 2  158 ? 19.85817  -16.16275 13.29668  1.000 28.74352 ? 158 LEU B N   1 
ATOM   2663 C CA  . LEU B 2  158 ? 20.67907  -16.98269 12.41474  1.000 33.84013 ? 158 LEU B CA  1 
ATOM   2664 C C   . LEU B 2  158 ? 19.96639  -18.30834 12.19244  1.000 41.27133 ? 158 LEU B C   1 
ATOM   2665 O O   . LEU B 2  158 ? 19.62465  -19.00096 13.15732  1.000 42.00885 ? 158 LEU B O   1 
ATOM   2666 C CB  . LEU B 2  158 ? 22.06971  -17.21025 13.01274  1.000 43.28299 ? 158 LEU B CB  1 
ATOM   2667 C CG  . LEU B 2  158 ? 23.19167  -16.23561 12.64400  1.000 45.13164 ? 158 LEU B CG  1 
ATOM   2668 C CD1 . LEU B 2  158 ? 22.81701  -14.79897 12.97853  1.000 43.76742 ? 158 LEU B CD1 1 
ATOM   2669 C CD2 . LEU B 2  158 ? 24.48017  -16.62912 13.35154  1.000 47.59187 ? 158 LEU B CD2 1 
ATOM   2670 N N   . VAL B 2  159 ? 19.73863  -18.65651 10.92883  1.000 36.68542 ? 159 VAL B N   1 
ATOM   2671 C CA  . VAL B 2  159 ? 19.04444  -19.88501 10.55808  1.000 39.34990 ? 159 VAL B CA  1 
ATOM   2672 C C   . VAL B 2  159 ? 19.99145  -20.72555 9.71433   1.000 43.03373 ? 159 VAL B C   1 
ATOM   2673 O O   . VAL B 2  159 ? 20.36663  -20.32475 8.60502   1.000 41.20514 ? 159 VAL B O   1 
ATOM   2674 C CB  . VAL B 2  159 ? 17.73794  -19.59991 9.80178   1.000 40.59797 ? 159 VAL B CB  1 
ATOM   2675 C CG1 . VAL B 2  159 ? 16.98768  -20.89545 9.53896   1.000 44.43050 ? 159 VAL B CG1 1 
ATOM   2676 C CG2 . VAL B 2  159 ? 16.87082  -18.62691 10.58924  1.000 36.67528 ? 159 VAL B CG2 1 
ATOM   2677 N N   . MET B 2  160 ? 20.37083  -21.88740 10.23554  1.000 47.23048 ? 160 MET B N   1 
ATOM   2678 C CA  . MET B 2  160 ? 21.33203  -22.76540 9.58804   1.000 49.42449 ? 160 MET B CA  1 
ATOM   2679 C C   . MET B 2  160 ? 20.62256  -23.89112 8.84654   1.000 53.41091 ? 160 MET B C   1 
ATOM   2680 O O   . MET B 2  160 ? 19.50378  -24.28020 9.19007   1.000 54.35560 ? 160 MET B O   1 
ATOM   2681 C CB  . MET B 2  160 ? 22.30375  -23.35405 10.61217  1.000 51.02385 ? 160 MET B CB  1 
ATOM   2682 C CG  . MET B 2  160 ? 23.38617  -22.39054 11.05944  1.000 53.40296 ? 160 MET B CG  1 
ATOM   2683 S SD  . MET B 2  160 ? 22.99124  -21.58367 12.62054  1.000 69.41049 ? 160 MET B SD  1 
ATOM   2684 C CE  . MET B 2  160 ? 23.10564  -22.96634 13.75289  1.000 65.18719 ? 160 MET B CE  1 
ATOM   2685 N N   . LEU B 2  161 ? 21.29220  -24.41310 7.82086   1.000 50.85338 ? 161 LEU B N   1 
ATOM   2686 C CA  . LEU B 2  161 ? 20.78237  -25.52356 7.02600   1.000 53.49927 ? 161 LEU B CA  1 
ATOM   2687 C C   . LEU B 2  161 ? 21.88691  -26.55592 6.87080   1.000 56.94521 ? 161 LEU B C   1 
ATOM   2688 O O   . LEU B 2  161 ? 22.97754  -26.23207 6.38906   1.000 59.64127 ? 161 LEU B O   1 
ATOM   2689 C CB  . LEU B 2  161 ? 20.29606  -25.04810 5.65323   1.000 49.55756 ? 161 LEU B CB  1 
ATOM   2690 C CG  . LEU B 2  161 ? 20.08661  -26.12932 4.58889   1.000 56.19885 ? 161 LEU B CG  1 
ATOM   2691 C CD1 . LEU B 2  161 ? 19.05383  -27.15300 5.04278   1.000 59.82027 ? 161 LEU B CD1 1 
ATOM   2692 C CD2 . LEU B 2  161 ? 19.68484  -25.50947 3.25776   1.000 53.46906 ? 161 LEU B CD2 1 
ATOM   2693 N N   . GLU B 2  162 ? 21.60840  -27.78993 7.28479   1.000 62.14712 ? 162 GLU B N   1 
ATOM   2694 C CA  . GLU B 2  162 ? 22.53843  -28.89281 7.06877   1.000 61.03245 ? 162 GLU B CA  1 
ATOM   2695 C C   . GLU B 2  162 ? 22.60938  -29.18631 5.57663   1.000 63.21940 ? 162 GLU B C   1 
ATOM   2696 O O   . GLU B 2  162 ? 21.63199  -29.64809 4.97930   1.000 66.85029 ? 162 GLU B O   1 
ATOM   2697 C CB  . GLU B 2  162 ? 22.09495  -30.12459 7.85170   1.000 64.93170 ? 162 GLU B CB  1 
ATOM   2698 N N   . MET B 2  163 ? 23.75787  -28.91070 4.96873   1.000 66.32248 ? 163 MET B N   1 
ATOM   2699 C CA  . MET B 2  163 ? 23.92023  -29.02432 3.52976   1.000 68.69161 ? 163 MET B CA  1 
ATOM   2700 C C   . MET B 2  163 ? 24.95697  -30.08543 3.19282   1.000 75.92073 ? 163 MET B C   1 
ATOM   2701 O O   . MET B 2  163 ? 25.85611  -30.38085 3.98667   1.000 79.24145 ? 163 MET B O   1 
ATOM   2702 C CB  . MET B 2  163 ? 24.33700  -27.68332 2.91067   1.000 70.57974 ? 163 MET B CB  1 
ATOM   2703 C CG  . MET B 2  163 ? 25.82302  -27.38189 3.03313   1.000 70.24198 ? 163 MET B CG  1 
ATOM   2704 S SD  . MET B 2  163 ? 26.25258  -25.70613 2.53206   1.000 77.67992 ? 163 MET B SD  1 
ATOM   2705 C CE  . MET B 2  163 ? 28.04134  -25.80499 2.52590   1.000 66.36826 ? 163 MET B CE  1 
ATOM   2706 N N   . THR B 2  164 ? 24.81011  -30.66240 2.00503   1.000 76.88697 ? 164 THR B N   1 
ATOM   2707 C CA  . THR B 2  164 ? 25.81291  -31.55462 1.42689   1.000 84.52233 ? 164 THR B CA  1 
ATOM   2708 C C   . THR B 2  164 ? 26.31162  -30.90896 0.14425   1.000 85.54791 ? 164 THR B C   1 
ATOM   2709 O O   . THR B 2  164 ? 25.60311  -30.93266 -0.87874  1.000 82.00299 ? 164 THR B O   1 
ATOM   2710 C CB  . THR B 2  164 ? 25.23461  -32.94049 1.14623   1.000 82.22639 ? 164 THR B CB  1 
ATOM   2711 N N   . PRO B 2  165 ? 27.50297  -30.29034 0.15284   1.000 85.88786 ? 165 PRO B N   1 
ATOM   2712 C CA  . PRO B 2  165 ? 28.03124  -29.67683 -1.07406  1.000 91.26772 ? 165 PRO B CA  1 
ATOM   2713 C C   . PRO B 2  165 ? 28.04572  -30.64742 -2.24273  1.000 91.64217 ? 165 PRO B C   1 
ATOM   2714 O O   . PRO B 2  165 ? 28.88830  -31.54878 -2.31165  1.000 89.20546 ? 165 PRO B O   1 
ATOM   2715 C CB  . PRO B 2  165 ? 29.44749  -29.25238 -0.66577  1.000 84.09287 ? 165 PRO B CB  1 
ATOM   2716 C CG  . PRO B 2  165 ? 29.33463  -29.00586 0.80200   1.000 84.22128 ? 165 PRO B CG  1 
ATOM   2717 C CD  . PRO B 2  165 ? 28.39952  -30.07553 1.30214   1.000 83.18353 ? 165 PRO B CD  1 
ATOM   2718 N N   . GLN B 2  166 ? 27.09328  -30.47264 -3.16078  1.000 87.45335 ? 166 GLN B N   1 
ATOM   2719 C CA  . GLN B 2  166 ? 26.89559  -31.39655 -4.27969  1.000 86.96333 ? 166 GLN B CA  1 
ATOM   2720 C C   . GLN B 2  166 ? 26.68217  -30.57042 -5.54920  1.000 89.79760 ? 166 GLN B C   1 
ATOM   2721 O O   . GLN B 2  166 ? 25.54532  -30.22534 -5.89396  1.000 87.84779 ? 166 GLN B O   1 
ATOM   2722 C CB  . GLN B 2  166 ? 25.73061  -32.33991 -4.01659  1.000 84.06429 ? 166 GLN B CB  1 
ATOM   2723 N N   . ARG B 2  167 ? 27.78300  -30.25904 -6.22642  1.000 91.17276 ? 167 ARG B N   1 
ATOM   2724 C CA  . ARG B 2  167 ? 27.79182  -29.66067 -7.56983  1.000 81.51735 ? 167 ARG B CA  1 
ATOM   2725 C C   . ARG B 2  167 ? 27.05046  -28.32014 -7.50492  1.000 84.26941 ? 167 ARG B C   1 
ATOM   2726 O O   . ARG B 2  167 ? 27.23680  -27.56387 -6.54009  1.000 82.39225 ? 167 ARG B O   1 
ATOM   2727 C CB  . ARG B 2  167 ? 27.24105  -30.66731 -8.56201  1.000 77.98460 ? 167 ARG B CB  1 
ATOM   2728 N N   . GLY B 2  168 ? 26.21712  -27.99360 -8.49311  1.000 78.18545 ? 168 GLY B N   1 
ATOM   2729 C CA  . GLY B 2  168 ? 25.56023  -26.69984 -8.52637  1.000 71.81848 ? 168 GLY B CA  1 
ATOM   2730 C C   . GLY B 2  168 ? 24.21979  -26.65708 -7.82362  1.000 71.72198 ? 168 GLY B C   1 
ATOM   2731 O O   . GLY B 2  168 ? 23.21348  -26.23525 -8.40435  1.000 67.81540 ? 168 GLY B O   1 
ATOM   2732 N N   . ASP B 2  169 ? 24.19722  -27.10257 -6.57130  1.000 77.21704 ? 169 ASP B N   1 
ATOM   2733 C CA  . ASP B 2  169 ? 23.01327  -26.94419 -5.74240  1.000 70.45131 ? 169 ASP B CA  1 
ATOM   2734 C C   . ASP B 2  169 ? 22.80540  -25.46641 -5.44322  1.000 62.83626 ? 169 ASP B C   1 
ATOM   2735 O O   . ASP B 2  169 ? 23.71670  -24.78530 -4.96287  1.000 65.15526 ? 169 ASP B O   1 
ATOM   2736 C CB  . ASP B 2  169 ? 23.16177  -27.74227 -4.44838  1.000 74.63754 ? 169 ASP B CB  1 
ATOM   2737 C CG  . ASP B 2  169 ? 22.78114  -29.20133 -4.61562  1.000 76.87138 ? 169 ASP B CG  1 
ATOM   2738 O OD1 . ASP B 2  169 ? 22.20302  -29.55102 -5.66613  1.000 71.83072 ? 169 ASP B OD1 1 
ATOM   2739 O OD2 . ASP B 2  169 ? 23.05392  -29.99783 -3.69283  1.000 83.17710 ? 169 ASP B OD2 1 
ATOM   2740 N N   . VAL B 2  170 ? 21.61406  -24.96699 -5.74713  1.000 59.85863 ? 170 VAL B N   1 
ATOM   2741 C CA  . VAL B 2  170 ? 21.29071  -23.55391 -5.59967  1.000 59.04511 ? 170 VAL B CA  1 
ATOM   2742 C C   . VAL B 2  170 ? 20.52936  -23.38192 -4.29255  1.000 55.88765 ? 170 VAL B C   1 
ATOM   2743 O O   . VAL B 2  170 ? 19.37430  -23.80492 -4.17370  1.000 53.36929 ? 170 VAL B O   1 
ATOM   2744 C CB  . VAL B 2  170 ? 20.47941  -23.03389 -6.79247  1.000 53.63202 ? 170 VAL B CB  1 
ATOM   2745 C CG1 . VAL B 2  170 ? 20.15169  -21.56273 -6.60419  1.000 50.31526 ? 170 VAL B CG1 1 
ATOM   2746 C CG2 . VAL B 2  170 ? 21.24538  -23.25677 -8.08855  1.000 57.60338 ? 170 VAL B CG2 1 
ATOM   2747 N N   . TYR B 2  171 ? 21.17487  -22.75787 -3.31175  1.000 51.52252 ? 171 TYR B N   1 
ATOM   2748 C CA  . TYR B 2  171 ? 20.57442  -22.49475 -2.01238  1.000 47.81870 ? 171 TYR B CA  1 
ATOM   2749 C C   . TYR B 2  171 ? 20.05850  -21.06267 -1.95936  1.000 44.45033 ? 171 TYR B C   1 
ATOM   2750 O O   . TYR B 2  171 ? 20.74250  -20.12885 -2.38931  1.000 41.42476 ? 171 TYR B O   1 
ATOM   2751 C CB  . TYR B 2  171 ? 21.58487  -22.72578 -0.88852  1.000 39.67178 ? 171 TYR B CB  1 
ATOM   2752 C CG  . TYR B 2  171 ? 22.10958  -24.14137 -0.80448  1.000 50.42432 ? 171 TYR B CG  1 
ATOM   2753 C CD1 . TYR B 2  171 ? 21.47750  -25.09078 -0.01233  1.000 56.61531 ? 171 TYR B CD1 1 
ATOM   2754 C CD2 . TYR B 2  171 ? 23.24276  -24.52627 -1.51020  1.000 54.31618 ? 171 TYR B CD2 1 
ATOM   2755 C CE1 . TYR B 2  171 ? 21.95634  -26.38520 0.07226   1.000 62.02058 ? 171 TYR B CE1 1 
ATOM   2756 C CE2 . TYR B 2  171 ? 23.72833  -25.81870 -1.43303  1.000 60.44509 ? 171 TYR B CE2 1 
ATOM   2757 C CZ  . TYR B 2  171 ? 23.08111  -26.74393 -0.64050  1.000 65.73172 ? 171 TYR B CZ  1 
ATOM   2758 O OH  . TYR B 2  171 ? 23.56051  -28.03161 -0.55938  1.000 68.51367 ? 171 TYR B OH  1 
ATOM   2759 N N   . THR B 2  172 ? 18.85038  -20.89409 -1.42420  1.000 37.23057 ? 172 THR B N   1 
ATOM   2760 C CA  . THR B 2  172 ? 18.20495  -19.58900 -1.37003  1.000 34.73187 ? 172 THR B CA  1 
ATOM   2761 C C   . THR B 2  172 ? 17.57538  -19.38097 -0.00161  1.000 46.75633 ? 172 THR B C   1 
ATOM   2762 O O   . THR B 2  172 ? 16.81669  -20.23265 0.47136   1.000 43.59190 ? 172 THR B O   1 
ATOM   2763 C CB  . THR B 2  172 ? 17.13450  -19.45201 -2.46048  1.000 41.16776 ? 172 THR B CB  1 
ATOM   2764 O OG1 . THR B 2  172 ? 17.74120  -19.58550 -3.75249  1.000 50.29219 ? 172 THR B OG1 1 
ATOM   2765 C CG2 . THR B 2  172 ? 16.44846  -18.09832 -2.36554  1.000 36.14007 ? 172 THR B CG2 1 
ATOM   2766 N N   . CYS B 2  173 ? 17.88843  -18.25076 0.62735   1.000 38.54600 ? 173 CYS B N   1 
ATOM   2767 C CA  . CYS B 2  173 ? 17.26063  -17.85083 1.87920   1.000 37.67183 ? 173 CYS B CA  1 
ATOM   2768 C C   . CYS B 2  173 ? 16.11473  -16.89427 1.57748   1.000 34.50586 ? 173 CYS B C   1 
ATOM   2769 O O   . CYS B 2  173 ? 16.27146  -15.96130 0.78319   1.000 37.92856 ? 173 CYS B O   1 
ATOM   2770 C CB  . CYS B 2  173 ? 18.26842  -17.19337 2.82378   1.000 36.41345 ? 173 CYS B CB  1 
ATOM   2771 S SG  . CYS B 2  173 ? 17.61128  -16.91380 4.48407   1.000 45.75210 ? 173 CYS B SG  1 
ATOM   2772 N N   . HIS B 2  174 ? 14.97046  -17.12649 2.21815   1.000 37.09567 ? 174 HIS B N   1 
ATOM   2773 C CA  . HIS B 2  174 ? 13.73128  -16.41196 1.93075   1.000 34.34204 ? 174 HIS B CA  1 
ATOM   2774 C C   . HIS B 2  174 ? 13.21167  -15.81297 3.22989   1.000 35.06034 ? 174 HIS B C   1 
ATOM   2775 O O   . HIS B 2  174 ? 12.91474  -16.54841 4.17633   1.000 32.58065 ? 174 HIS B O   1 
ATOM   2776 C CB  . HIS B 2  174 ? 12.70731  -17.36544 1.30232   1.000 39.27888 ? 174 HIS B CB  1 
ATOM   2777 C CG  . HIS B 2  174 ? 11.33678  -16.78522 1.14061   1.000 42.48861 ? 174 HIS B CG  1 
ATOM   2778 N ND1 . HIS B 2  174 ? 10.85479  -16.34712 -0.07427  1.000 48.25653 ? 174 HIS B ND1 1 
ATOM   2779 C CD2 . HIS B 2  174 ? 10.33111  -16.60726 2.02999   1.000 47.79440 ? 174 HIS B CD2 1 
ATOM   2780 C CE1 . HIS B 2  174 ? 9.61887   -15.90565 0.07754   1.000 42.20717 ? 174 HIS B CE1 1 
ATOM   2781 N NE2 . HIS B 2  174 ? 9.27753   -16.05154 1.34519   1.000 48.74470 ? 174 HIS B NE2 1 
ATOM   2782 N N   . VAL B 2  175 ? 13.10008  -14.48613 3.27618   1.000 29.33384 ? 175 VAL B N   1 
ATOM   2783 C CA  . VAL B 2  175 ? 12.82087  -13.75678 4.50846   1.000 32.85812 ? 175 VAL B CA  1 
ATOM   2784 C C   . VAL B 2  175 ? 11.58597  -12.88897 4.31128   1.000 29.65924 ? 175 VAL B C   1 
ATOM   2785 O O   . VAL B 2  175 ? 11.50124  -12.13308 3.33649   1.000 26.99769 ? 175 VAL B O   1 
ATOM   2786 C CB  . VAL B 2  175 ? 14.02269  -12.89413 4.93700   1.000 28.35048 ? 175 VAL B CB  1 
ATOM   2787 C CG1 . VAL B 2  175 ? 13.64600  -12.00152 6.11122   1.000 32.76368 ? 175 VAL B CG1 1 
ATOM   2788 C CG2 . VAL B 2  175 ? 15.20797  -13.77524 5.29032   1.000 26.73925 ? 175 VAL B CG2 1 
ATOM   2789 N N   . GLU B 2  176 ? 10.64253  -12.98505 5.24831   1.000 28.62836 ? 176 GLU B N   1 
ATOM   2790 C CA  . GLU B 2  176 ? 9.44999   -12.14907 5.27538   1.000 34.26024 ? 176 GLU B CA  1 
ATOM   2791 C C   . GLU B 2  176 ? 9.40110   -11.38067 6.58971   1.000 33.23589 ? 176 GLU B C   1 
ATOM   2792 O O   . GLU B 2  176 ? 9.73400   -11.92348 7.64778   1.000 29.22498 ? 176 GLU B O   1 
ATOM   2793 C CB  . GLU B 2  176 ? 8.17936   -12.98991 5.10635   1.000 38.74853 ? 176 GLU B CB  1 
ATOM   2794 C CG  . GLU B 2  176 ? 8.26005   -14.01271 3.98201   1.000 45.49129 ? 176 GLU B CG  1 
ATOM   2795 C CD  . GLU B 2  176 ? 6.99990   -14.84774 3.86080   1.000 60.56140 ? 176 GLU B CD  1 
ATOM   2796 O OE1 . GLU B 2  176 ? 5.93672   -14.27592 3.54066   1.000 59.26542 ? 176 GLU B OE1 1 
ATOM   2797 O OE2 . GLU B 2  176 ? 7.07249   -16.07511 4.08459   1.000 57.40841 ? 176 GLU B OE2 1 
ATOM   2798 N N   . HIS B 2  177 ? 8.97565   -10.11914 6.52042   1.000 28.95355 ? 177 HIS B N   1 
ATOM   2799 C CA  . HIS B 2  177 ? 9.04168   -9.21749  7.66289   1.000 31.96753 ? 177 HIS B CA  1 
ATOM   2800 C C   . HIS B 2  177 ? 8.06775   -8.07290  7.42939   1.000 30.31840 ? 177 HIS B C   1 
ATOM   2801 O O   . HIS B 2  177 ? 7.86702   -7.66600  6.27956   1.000 32.54536 ? 177 HIS B O   1 
ATOM   2802 C CB  . HIS B 2  177 ? 10.47253  -8.68567  7.85486   1.000 31.14928 ? 177 HIS B CB  1 
ATOM   2803 C CG  . HIS B 2  177 ? 10.64986  -7.83591  9.07449   1.000 26.75109 ? 177 HIS B CG  1 
ATOM   2804 N ND1 . HIS B 2  177 ? 10.56337  -6.46111  9.04229   1.000 27.23851 ? 177 HIS B ND1 1 
ATOM   2805 C CD2 . HIS B 2  177 ? 10.90674  -8.16610  10.36233  1.000 24.44184 ? 177 HIS B CD2 1 
ATOM   2806 C CE1 . HIS B 2  177 ? 10.75766  -5.98057  10.25744  1.000 26.70871 ? 177 HIS B CE1 1 
ATOM   2807 N NE2 . HIS B 2  177 ? 10.96669  -6.99447  11.07752  1.000 25.60940 ? 177 HIS B NE2 1 
ATOM   2808 N N   . PRO B 2  178 ? 7.44626   -7.53809  8.48684   1.000 31.28283 ? 178 PRO B N   1 
ATOM   2809 C CA  . PRO B 2  178 ? 6.45698   -6.46115  8.29528   1.000 31.44766 ? 178 PRO B CA  1 
ATOM   2810 C C   . PRO B 2  178 ? 7.00723   -5.21314  7.62447   1.000 38.54629 ? 178 PRO B C   1 
ATOM   2811 O O   . PRO B 2  178 ? 6.21700   -4.40466  7.12210   1.000 35.90921 ? 178 PRO B O   1 
ATOM   2812 C CB  . PRO B 2  178 ? 5.98812   -6.15792  9.72487   1.000 33.12014 ? 178 PRO B CB  1 
ATOM   2813 C CG  . PRO B 2  178 ? 6.23996   -7.41177  10.47910  1.000 29.98674 ? 178 PRO B CG  1 
ATOM   2814 C CD  . PRO B 2  178 ? 7.47116   -8.02203  9.87776   1.000 28.77601 ? 178 PRO B CD  1 
ATOM   2815 N N   . SER B 2  179 ? 8.32507   -5.01730  7.60629   1.000 31.84135 ? 179 SER B N   1 
ATOM   2816 C CA  . SER B 2  179 ? 8.89939   -3.85820  6.93609   1.000 31.52898 ? 179 SER B CA  1 
ATOM   2817 C C   . SER B 2  179 ? 8.99239   -4.02980  5.42624   1.000 33.95289 ? 179 SER B C   1 
ATOM   2818 O O   . SER B 2  179 ? 9.22283   -3.04147  4.72146   1.000 39.89783 ? 179 SER B O   1 
ATOM   2819 C CB  . SER B 2  179 ? 10.29300  -3.56425  7.49286   1.000 35.80556 ? 179 SER B CB  1 
ATOM   2820 O OG  . SER B 2  179 ? 11.22277  -4.53257  7.04027   1.000 25.92965 ? 179 SER B OG  1 
ATOM   2821 N N   . LEU B 2  180 ? 8.81977   -5.24534  4.91660   1.000 31.57421 ? 180 LEU B N   1 
ATOM   2822 C CA  . LEU B 2  180 ? 9.03058   -5.54567  3.50710   1.000 37.12885 ? 180 LEU B CA  1 
ATOM   2823 C C   . LEU B 2  180 ? 7.69378   -5.67119  2.78903   1.000 43.48197 ? 180 LEU B C   1 
ATOM   2824 O O   . LEU B 2  180 ? 6.82613   -6.44285  3.21166   1.000 44.83985 ? 180 LEU B O   1 
ATOM   2825 C CB  . LEU B 2  180 ? 9.83115   -6.83862  3.34539   1.000 34.95291 ? 180 LEU B CB  1 
ATOM   2826 C CG  . LEU B 2  180 ? 11.16808  -6.91595  4.08261   1.000 34.64943 ? 180 LEU B CG  1 
ATOM   2827 C CD1 . LEU B 2  180 ? 11.68896  -8.34484  4.09336   1.000 31.40181 ? 180 LEU B CD1 1 
ATOM   2828 C CD2 . LEU B 2  180 ? 12.17618  -5.97774  3.44555   1.000 31.44333 ? 180 LEU B CD2 1 
ATOM   2829 N N   . GLN B 2  181 ? 7.53277   -4.91248  1.70222   1.000 39.75540 ? 181 GLN B N   1 
ATOM   2830 C CA  . GLN B 2  181 ? 6.35866   -5.08870  0.85508   1.000 42.39998 ? 181 GLN B CA  1 
ATOM   2831 C C   . GLN B 2  181 ? 6.39936   -6.42509  0.12548   1.000 44.37669 ? 181 GLN B C   1 
ATOM   2832 O O   . GLN B 2  181 ? 5.34904   -7.02549  -0.12953  1.000 47.24768 ? 181 GLN B O   1 
ATOM   2833 C CB  . GLN B 2  181 ? 6.25315   -3.93749  -0.14532  1.000 44.12397 ? 181 GLN B CB  1 
ATOM   2834 N N   . SER B 2  182 ? 7.59302   -6.90192  -0.21141  1.000 36.48042 ? 182 SER B N   1 
ATOM   2835 C CA  . SER B 2  182 ? 7.81418   -8.18763  -0.84973  1.000 42.80572 ? 182 SER B CA  1 
ATOM   2836 C C   . SER B 2  182 ? 8.92854   -8.92288  -0.12208  1.000 37.68361 ? 182 SER B C   1 
ATOM   2837 O O   . SER B 2  182 ? 9.82576   -8.29004  0.44320   1.000 36.06161 ? 182 SER B O   1 
ATOM   2838 C CB  . SER B 2  182 ? 8.18848   -8.01889  -2.33074  1.000 41.83607 ? 182 SER B CB  1 
ATOM   2839 O OG  . SER B 2  182 ? 7.52502   -6.90490  -2.90218  1.000 54.96052 ? 182 SER B OG  1 
ATOM   2840 N N   . PRO B 2  183 ? 8.89812   -10.25409 -0.11491  1.000 37.00883 ? 183 PRO B N   1 
ATOM   2841 C CA  . PRO B 2  183 ? 9.93384   -11.00518 0.60220   1.000 31.86437 ? 183 PRO B CA  1 
ATOM   2842 C C   . PRO B 2  183 ? 11.30407  -10.82705 -0.03060  1.000 37.47789 ? 183 PRO B C   1 
ATOM   2843 O O   . PRO B 2  183 ? 11.43733  -10.58641 -1.23270  1.000 34.75486 ? 183 PRO B O   1 
ATOM   2844 C CB  . PRO B 2  183 ? 9.46064   -12.45995 0.49598   1.000 38.86921 ? 183 PRO B CB  1 
ATOM   2845 C CG  . PRO B 2  183 ? 8.54837   -12.48399 -0.68303  1.000 42.21793 ? 183 PRO B CG  1 
ATOM   2846 C CD  . PRO B 2  183 ? 7.88983   -11.13866 -0.72425  1.000 42.21275 ? 183 PRO B CD  1 
ATOM   2847 N N   . ILE B 2  184 ? 12.33102  -10.94045 0.80491   1.000 32.19843 ? 184 ILE B N   1 
ATOM   2848 C CA  . ILE B 2  184 ? 13.71488  -10.88323 0.35123   1.000 31.86639 ? 184 ILE B CA  1 
ATOM   2849 C C   . ILE B 2  184 ? 14.18922  -12.30103 0.07091   1.000 28.61519 ? 184 ILE B C   1 
ATOM   2850 O O   . ILE B 2  184 ? 13.99323  -13.20585 0.89109   1.000 28.99281 ? 184 ILE B O   1 
ATOM   2851 C CB  . ILE B 2  184 ? 14.61319  -10.19925 1.39593   1.000 30.51206 ? 184 ILE B CB  1 
ATOM   2852 C CG1 . ILE B 2  184 ? 14.40351  -8.68473  1.38493   1.000 32.31720 ? 184 ILE B CG1 1 
ATOM   2853 C CG2 . ILE B 2  184 ? 16.07845  -10.52691 1.14111   1.000 26.99587 ? 184 ILE B CG2 1 
ATOM   2854 C CD1 . ILE B 2  184 ? 15.15604  -7.96302  2.49253   1.000 28.04352 ? 184 ILE B CD1 1 
ATOM   2855 N N   . THR B 2  185 ? 14.80448  -12.49942 -1.09088  1.000 28.94075 ? 185 THR B N   1 
ATOM   2856 C CA  . THR B 2  185 ? 15.39371  -13.77835 -1.46293  1.000 31.77744 ? 185 THR B CA  1 
ATOM   2857 C C   . THR B 2  185 ? 16.85727  -13.54849 -1.80522  1.000 29.96842 ? 185 THR B C   1 
ATOM   2858 O O   . THR B 2  185 ? 17.17356  -12.72679 -2.67148  1.000 29.67992 ? 185 THR B O   1 
ATOM   2859 C CB  . THR B 2  185 ? 14.65348  -14.41165 -2.64275  1.000 34.87855 ? 185 THR B CB  1 
ATOM   2860 O OG1 . THR B 2  185 ? 14.38060  -13.41011 -3.62994  1.000 36.42999 ? 185 THR B OG1 1 
ATOM   2861 C CG2 . THR B 2  185 ? 13.34056  -15.02909 -2.17515  1.000 35.77458 ? 185 THR B CG2 1 
ATOM   2862 N N   . VAL B 2  186 ? 17.74222  -14.26304 -1.11699  1.000 31.26941 ? 186 VAL B N   1 
ATOM   2863 C CA  . VAL B 2  186 ? 19.18072  -14.16816 -1.32079  1.000 31.25754 ? 186 VAL B CA  1 
ATOM   2864 C C   . VAL B 2  186 ? 19.68477  -15.54103 -1.73934  1.000 35.20686 ? 186 VAL B C   1 
ATOM   2865 O O   . VAL B 2  186 ? 19.28305  -16.55833 -1.16462  1.000 34.57624 ? 186 VAL B O   1 
ATOM   2866 C CB  . VAL B 2  186 ? 19.89929  -13.66962 -0.04787  1.000 28.95700 ? 186 VAL B CB  1 
ATOM   2867 C CG1 . VAL B 2  186 ? 21.39340  -13.94551 -0.12166  1.000 32.41455 ? 186 VAL B CG1 1 
ATOM   2868 C CG2 . VAL B 2  186 ? 19.63894  -12.18556 0.15577   1.000 23.75327 ? 186 VAL B CG2 1 
ATOM   2869 N N   . GLU B 2  187 ? 20.55359  -15.57021 -2.74623  1.000 34.69741 ? 187 GLU B N   1 
ATOM   2870 C CA  . GLU B 2  187 ? 21.00838  -16.81074 -3.35668  1.000 39.55825 ? 187 GLU B CA  1 
ATOM   2871 C C   . GLU B 2  187 ? 22.47794  -17.05866 -3.04384  1.000 37.91986 ? 187 GLU B C   1 
ATOM   2872 O O   . GLU B 2  187 ? 23.29422  -16.13180 -3.06602  1.000 38.35752 ? 187 GLU B O   1 
ATOM   2873 C CB  . GLU B 2  187 ? 20.79947  -16.77644 -4.87342  1.000 34.10514 ? 187 GLU B CB  1 
ATOM   2874 C CG  . GLU B 2  187 ? 21.18611  -18.06122 -5.58281  1.000 42.30132 ? 187 GLU B CG  1 
ATOM   2875 C CD  . GLU B 2  187 ? 20.73781  -18.08451 -7.02996  1.000 43.88266 ? 187 GLU B CD  1 
ATOM   2876 O OE1 . GLU B 2  187 ? 19.51272  -18.06336 -7.27334  1.000 42.45587 ? 187 GLU B OE1 1 
ATOM   2877 O OE2 . GLU B 2  187 ? 21.61047  -18.12641 -7.92314  1.000 47.51152 ? 187 GLU B OE2 1 
ATOM   2878 N N   . TRP B 2  188 ? 22.80768  -18.31795 -2.76023  1.000 38.05747 ? 188 TRP B N   1 
ATOM   2879 C CA  . TRP B 2  188 ? 24.17823  -18.74531 -2.51369  1.000 39.17714 ? 188 TRP B CA  1 
ATOM   2880 C C   . TRP B 2  188 ? 24.46390  -19.99661 -3.32724  1.000 45.44942 ? 188 TRP B C   1 
ATOM   2881 O O   . TRP B 2  188 ? 23.65517  -20.93027 -3.34204  1.000 47.49809 ? 188 TRP B O   1 
ATOM   2882 C CB  . TRP B 2  188 ? 24.42006  -19.02611 -1.02685  1.000 40.83921 ? 188 TRP B CB  1 
ATOM   2883 C CG  . TRP B 2  188 ? 25.84597  -19.37699 -0.68874  1.000 39.25621 ? 188 TRP B CG  1 
ATOM   2884 C CD1 . TRP B 2  188 ? 26.84440  -18.50961 -0.35133  1.000 39.87347 ? 188 TRP B CD1 1 
ATOM   2885 C CD2 . TRP B 2  188 ? 26.42576  -20.68946 -0.64674  1.000 39.42309 ? 188 TRP B CD2 1 
ATOM   2886 N NE1 . TRP B 2  188 ? 28.00808  -19.19801 -0.10479  1.000 42.84137 ? 188 TRP B NE1 1 
ATOM   2887 C CE2 . TRP B 2  188 ? 27.77824  -20.53709 -0.27943  1.000 41.99116 ? 188 TRP B CE2 1 
ATOM   2888 C CE3 . TRP B 2  188 ? 25.93384  -21.97627 -0.88653  1.000 38.77416 ? 188 TRP B CE3 1 
ATOM   2889 C CZ2 . TRP B 2  188 ? 28.64339  -21.62219 -0.14514  1.000 45.43486 ? 188 TRP B CZ2 1 
ATOM   2890 C CZ3 . TRP B 2  188 ? 26.79504  -23.05307 -0.75140  1.000 43.23796 ? 188 TRP B CZ3 1 
ATOM   2891 C CH2 . TRP B 2  188 ? 28.13374  -22.86860 -0.38417  1.000 46.76947 ? 188 TRP B CH2 1 
ATOM   2892 N N   . ARG B 2  189 ? 25.60606  -20.00862 -4.00356  1.000 44.56014 ? 189 ARG B N   1 
ATOM   2893 C CA  . ARG B 2  189 ? 26.08814  -21.20639 -4.67526  1.000 46.10251 ? 189 ARG B CA  1 
ATOM   2894 C C   . ARG B 2  189 ? 27.52215  -21.47311 -4.24723  1.000 49.28331 ? 189 ARG B C   1 
ATOM   2895 O O   . ARG B 2  189 ? 28.17682  -20.60467 -3.67115  1.000 58.03390 ? 189 ARG B O   1 
ATOM   2896 C CB  . ARG B 2  189 ? 26.01157  -21.06557 -6.19481  1.000 49.76493 ? 189 ARG B CB  1 
ATOM   2897 C CG  . ARG B 2  189 ? 24.60797  -21.00600 -6.76769  1.000 50.37952 ? 189 ARG B CG  1 
ATOM   2898 C CD  . ARG B 2  189 ? 24.64974  -20.34529 -8.12998  1.000 49.66998 ? 189 ARG B CD  1 
ATOM   2899 N NE  . ARG B 2  189 ? 23.33177  -20.04344 -8.67438  1.000 51.12401 ? 189 ARG B NE  1 
ATOM   2900 C CZ  . ARG B 2  189 ? 22.89391  -20.47375 -9.84993  1.000 50.69455 ? 189 ARG B CZ  1 
ATOM   2901 N NH1 . ARG B 2  189 ? 23.63941  -21.24482 -10.62546 1.000 46.29383 ? 189 ARG B NH1 1 
ATOM   2902 N NH2 . ARG B 2  189 ? 21.68044  -20.11687 -10.26048 1.000 47.86770 ? 189 ARG B NH2 1 
ATOM   2903 N N   . ALA B 2  195 ? 27.77378  -24.47772 -3.96773  1.000 63.36244 ? 193 ALA B N   1 
ATOM   2904 C CA  . ALA B 2  195 ? 29.13793  -24.38789 -3.45990  1.000 65.35446 ? 193 ALA B CA  1 
ATOM   2905 C C   . ALA B 2  195 ? 30.03270  -23.61290 -4.42280  1.000 71.76674 ? 193 ALA B C   1 
ATOM   2906 O O   . ALA B 2  195 ? 29.81141  -23.62130 -5.63404  1.000 75.76131 ? 193 ALA B O   1 
ATOM   2907 C CB  . ALA B 2  195 ? 29.70164  -25.77626 -3.21273  1.000 69.69640 ? 193 ALA B CB  1 
ATOM   2908 N N   . GLN B 2  196 ? 31.04285  -22.94416 -3.87543  1.000 70.91460 ? 194 GLN B N   1 
ATOM   2909 C CA  . GLN B 2  196 ? 31.97832  -22.16616 -4.68028  1.000 69.12116 ? 194 GLN B CA  1 
ATOM   2910 C C   . GLN B 2  196 ? 32.98850  -23.06658 -5.38337  1.000 68.22146 ? 194 GLN B C   1 
ATOM   2911 O O   . GLN B 2  196 ? 32.61665  -23.98113 -6.11895  1.000 63.15467 ? 194 GLN B O   1 
ATOM   2912 C CB  . GLN B 2  196 ? 32.70885  -21.14355 -3.80951  1.000 68.82201 ? 194 GLN B CB  1 
ATOM   2913 N N   . GLN C 3  1   ? -0.80738  15.19640  26.25168  1.000 62.67598 ? 0   GLN C N   1 
ATOM   2914 C CA  . GLN C 3  1   ? -0.79043  14.32456  27.42046  1.000 62.69035 ? 0   GLN C CA  1 
ATOM   2915 C C   . GLN C 3  1   ? 0.51173   13.53191  27.49451  1.000 57.47533 ? 0   GLN C C   1 
ATOM   2916 O O   . GLN C 3  1   ? 0.90604   12.88316  26.52527  1.000 59.60872 ? 0   GLN C O   1 
ATOM   2917 C CB  . GLN C 3  1   ? -1.98803  13.37185  27.39676  1.000 61.78200 ? 0   GLN C CB  1 
ATOM   2918 C CG  . GLN C 3  1   ? -3.31069  14.02589  27.76525  1.000 61.44565 ? 0   GLN C CG  1 
ATOM   2919 C CD  . GLN C 3  1   ? -4.33128  13.94946  26.64577  1.000 74.25839 ? 0   GLN C CD  1 
ATOM   2920 O OE1 . GLN C 3  1   ? -4.00670  14.16524  25.47749  1.000 72.10292 ? 0   GLN C OE1 1 
ATOM   2921 N NE2 . GLN C 3  1   ? -5.57415  13.64016  26.99829  1.000 77.20060 ? 0   GLN C NE2 1 
ATOM   2922 N N   . PRO C 3  2   ? 1.18093   13.58888  28.64157  1.000 51.41900 ? 1   PRO C N   1 
ATOM   2923 C CA  . PRO C 3  2   ? 2.43190   12.84795  28.81088  1.000 44.63181 ? 1   PRO C CA  1 
ATOM   2924 C C   . PRO C 3  2   ? 2.15907   11.38296  29.09732  1.000 43.64721 ? 1   PRO C C   1 
ATOM   2925 O O   . PRO C 3  2   ? 1.03319   11.01370  29.46375  1.000 43.95745 ? 1   PRO C O   1 
ATOM   2926 C CB  . PRO C 3  2   ? 3.08372   13.54076  30.01522  1.000 46.72736 ? 1   PRO C CB  1 
ATOM   2927 C CG  . PRO C 3  2   ? 1.92279   14.01054  30.82420  1.000 48.48019 ? 1   PRO C CG  1 
ATOM   2928 C CD  . PRO C 3  2   ? 0.84602   14.38993  29.83292  1.000 50.50214 ? 1   PRO C CD  1 
ATOM   2929 N N   . PRO C 3  3   ? 3.15590   10.51432  28.92688  1.000 43.20127 ? 2   PRO C N   1 
ATOM   2930 C CA  . PRO C 3  3   ? 2.97112   9.10459   29.29143  1.000 42.43453 ? 2   PRO C CA  1 
ATOM   2931 C C   . PRO C 3  3   ? 2.67104   8.94349   30.77485  1.000 42.51533 ? 2   PRO C C   1 
ATOM   2932 O O   . PRO C 3  3   ? 3.16504   9.69340   31.62036  1.000 42.59316 ? 2   PRO C O   1 
ATOM   2933 C CB  . PRO C 3  3   ? 4.31182   8.45534   28.91809  1.000 40.40545 ? 2   PRO C CB  1 
ATOM   2934 C CG  . PRO C 3  3   ? 5.25863   9.59134   28.65338  1.000 42.08834 ? 2   PRO C CG  1 
ATOM   2935 C CD  . PRO C 3  3   ? 4.42087   10.74049  28.21126  1.000 41.40320 ? 2   PRO C CD  1 
ATOM   2936 N N   . ALA C 3  4   ? 1.84601   7.94893   31.08247  1.000 34.79812 ? 3   ALA C N   1 
ATOM   2937 C CA  . ALA C 3  4   ? 1.44323   7.65194   32.44799  1.000 33.74930 ? 3   ALA C CA  1 
ATOM   2938 C C   . ALA C 3  4   ? 2.23751   6.47287   32.99721  1.000 28.70496 ? 3   ALA C C   1 
ATOM   2939 O O   . ALA C 3  4   ? 2.82195   5.68265   32.25238  1.000 27.91810 ? 3   ALA C O   1 
ATOM   2940 C CB  . ALA C 3  4   ? -0.05685  7.35257   32.51930  1.000 31.61205 ? 3   ALA C CB  1 
ATOM   2941 N N   . SER C 3  5   ? 2.24583   6.36208   34.32397  1.000 29.58088 ? 4   SER C N   1 
ATOM   2942 C CA  . SER C 3  5   ? 2.97735   5.30320   35.00161  1.000 28.51673 ? 4   SER C CA  1 
ATOM   2943 C C   . SER C 3  5   ? 2.22968   4.91794   36.27046  1.000 35.95855 ? 4   SER C C   1 
ATOM   2944 O O   . SER C 3  5   ? 1.51734   5.73438   36.86121  1.000 37.09338 ? 4   SER C O   1 
ATOM   2945 C CB  . SER C 3  5   ? 4.41098   5.73837   35.32426  1.000 26.63327 ? 4   SER C CB  1 
ATOM   2946 O OG  . SER C 3  5   ? 5.23188   4.62417   35.62628  1.000 31.62838 ? 4   SER C OG  1 
ATOM   2947 N N   . GLU C 3  6   ? 2.40123   3.66557   36.68460  1.000 33.88949 ? 5   GLU C N   1 
ATOM   2948 C CA  . GLU C 3  6   ? 1.65194   3.11156   37.80418  1.000 31.29270 ? 5   GLU C CA  1 
ATOM   2949 C C   . GLU C 3  6   ? 2.39804   3.31415   39.11710  1.000 29.13799 ? 5   GLU C C   1 
ATOM   2950 O O   . GLU C 3  6   ? 3.60953   3.09469   39.20089  1.000 28.98832 ? 5   GLU C O   1 
ATOM   2951 C CB  . GLU C 3  6   ? 1.38144   1.62223   37.57700  1.000 30.43038 ? 5   GLU C CB  1 
ATOM   2952 C CG  . GLU C 3  6   ? 0.50046   0.96424   38.63038  1.000 36.78741 ? 5   GLU C CG  1 
ATOM   2953 C CD  . GLU C 3  6   ? -0.92997  1.47792   38.62347  1.000 37.44231 ? 5   GLU C CD  1 
ATOM   2954 O OE1 . GLU C 3  6   ? -1.30900  2.21632   37.68983  1.000 42.79470 ? 5   GLU C OE1 1 
ATOM   2955 O OE2 . GLU C 3  6   ? -1.68163  1.13355   39.55651  1.000 36.86961 ? 5   GLU C OE2 1 
ATOM   2956 N N   . GLN C 3  7   ? 1.66305   3.73049   40.14350  1.000 32.60246 ? 6   GLN C N   1 
ATOM   2957 C CA  . GLN C 3  7   ? 2.24005   3.97409   41.45654  1.000 35.34068 ? 6   GLN C CA  1 
ATOM   2958 C C   . GLN C 3  7   ? 2.21716   2.70939   42.30440  1.000 29.88641 ? 6   GLN C C   1 
ATOM   2959 O O   . GLN C 3  7   ? 1.30113   1.88850   42.21053  1.000 32.01665 ? 6   GLN C O   1 
ATOM   2960 C CB  . GLN C 3  7   ? 1.48485   5.08490   42.18801  1.000 36.57508 ? 6   GLN C CB  1 
ATOM   2961 C CG  . GLN C 3  7   ? 1.51052   6.43403   41.49623  1.000 45.90954 ? 6   GLN C CG  1 
ATOM   2962 C CD  . GLN C 3  7   ? 0.62671   7.45114   42.19180  1.000 53.27169 ? 6   GLN C CD  1 
ATOM   2963 O OE1 . GLN C 3  7   ? -0.52835  7.64856   41.81438  1.000 52.85811 ? 6   GLN C OE1 1 
ATOM   2964 N NE2 . GLN C 3  7   ? 1.16569   8.10019   43.21704  1.000 51.34096 ? 6   GLN C NE2 1 
ATOM   2965 N N   . GLU C 3  8   ? 3.24081   2.56209   43.13811  1.000 30.09441 ? 7   GLU C N   1 
ATOM   2966 C CA  . GLU C 3  8   ? 3.25921   1.52706   44.15862  1.000 34.22571 ? 7   GLU C CA  1 
ATOM   2967 C C   . GLU C 3  8   ? 2.60872   2.05625   45.43172  1.000 31.36238 ? 7   GLU C C   1 
ATOM   2968 O O   . GLU C 3  8   ? 2.66176   3.25349   45.72554  1.000 28.84817 ? 7   GLU C O   1 
ATOM   2969 C CB  . GLU C 3  8   ? 4.69376   1.06503   44.43816  1.000 28.94517 ? 7   GLU C CB  1 
ATOM   2970 C CG  . GLU C 3  8   ? 4.87150   0.13243   45.64416  1.000 31.50201 ? 7   GLU C CG  1 
ATOM   2971 C CD  . GLU C 3  8   ? 4.23317   -1.24004  45.45731  1.000 35.31171 ? 7   GLU C CD  1 
ATOM   2972 O OE1 . GLU C 3  8   ? 2.99918   -1.31867  45.26915  1.000 30.37631 ? 7   GLU C OE1 1 
ATOM   2973 O OE2 . GLU C 3  8   ? 4.97037   -2.24844  45.51013  1.000 26.70972 ? 7   GLU C OE2 1 
ATOM   2974 N N   . GLN C 3  9   ? 1.97091   1.15294   46.17649  1.000 32.72751 ? 8   GLN C N   1 
ATOM   2975 C CA  . GLN C 3  9   ? 1.33082   1.56093   47.41970  1.000 31.22738 ? 8   GLN C CA  1 
ATOM   2976 C C   . GLN C 3  9   ? 2.23550   1.27872   48.61171  1.000 34.24070 ? 8   GLN C C   1 
ATOM   2977 O O   . GLN C 3  9   ? 2.92897   0.25558   48.63729  1.000 37.34308 ? 8   GLN C O   1 
ATOM   2978 C CB  . GLN C 3  9   ? 0.00367   0.82661   47.61515  1.000 30.44304 ? 8   GLN C CB  1 
ATOM   2979 C CG  . GLN C 3  9   ? -1.02783  1.10248   46.53552  1.000 38.06007 ? 8   GLN C CG  1 
ATOM   2980 C CD  . GLN C 3  9   ? -1.52917  2.53323   46.55756  1.000 42.47865 ? 8   GLN C CD  1 
ATOM   2981 O OE1 . GLN C 3  9   ? -1.86251  3.10031   45.51765  1.000 48.99450 ? 8   GLN C OE1 1 
ATOM   2982 N NE2 . GLN C 3  9   ? -1.58734  3.12421   47.74645  1.000 45.41362 ? 8   GLN C NE2 1 
ATOM   2983 N N   . PRO C 3  10  ? 2.25308   2.16280   49.60742  1.000 36.01957 ? 9   PRO C N   1 
ATOM   2984 C CA  . PRO C 3  10  ? 3.03215   1.88385   50.81902  1.000 35.01955 ? 9   PRO C CA  1 
ATOM   2985 C C   . PRO C 3  10  ? 2.39003   0.77935   51.64281  1.000 36.18039 ? 9   PRO C C   1 
ATOM   2986 O O   . PRO C 3  10  ? 1.16418   0.67279   51.72581  1.000 36.55201 ? 9   PRO C O   1 
ATOM   2987 C CB  . PRO C 3  10  ? 3.01537   3.22123   51.56880  1.000 33.76215 ? 9   PRO C CB  1 
ATOM   2988 C CG  . PRO C 3  10  ? 1.77935   3.90476   51.08078  1.000 37.68230 ? 9   PRO C CG  1 
ATOM   2989 C CD  . PRO C 3  10  ? 1.63444   3.49887   49.64013  1.000 38.30564 ? 9   PRO C CD  1 
ATOM   2990 N N   . VAL C 3  11  ? 3.23293   -0.05161  52.24768  1.000 37.12367 ? 10  VAL C N   1 
ATOM   2991 C CA  . VAL C 3  11  ? 2.76320   -1.08247  53.16027  1.000 39.65555 ? 10  VAL C CA  1 
ATOM   2992 C C   . VAL C 3  11  ? 2.68768   -0.49531  54.56395  1.000 45.70587 ? 10  VAL C C   1 
ATOM   2993 O O   . VAL C 3  11  ? 3.31220   0.52173   54.87578  1.000 49.52066 ? 10  VAL C O   1 
ATOM   2994 C CB  . VAL C 3  11  ? 3.66538   -2.33350  53.13149  1.000 41.10056 ? 10  VAL C CB  1 
ATOM   2995 C CG1 . VAL C 3  11  ? 3.61063   -3.00290  51.76520  1.000 32.27940 ? 10  VAL C CG1 1 
ATOM   2996 C CG2 . VAL C 3  11  ? 5.09431   -1.96884  53.50247  1.000 39.18314 ? 10  VAL C CG2 1 
ATOM   2997 N N   . LEU C 3  12  ? 1.91164   -1.14398  55.42311  1.000 46.67215 ? 11  LEU C N   1 
ATOM   2998 C CA  . LEU C 3  12  ? 1.78570   -0.65149  56.78785  1.000 47.35629 ? 11  LEU C CA  1 
ATOM   2999 C C   . LEU C 3  12  ? 2.96743   -1.12573  57.63291  1.000 51.10998 ? 11  LEU C C   1 
ATOM   3000 O O   . LEU C 3  12  ? 3.38054   -2.28378  57.52741  1.000 50.46354 ? 11  LEU C O   1 
ATOM   3001 C CB  . LEU C 3  12  ? 0.47697   -1.12680  57.41326  1.000 54.55323 ? 11  LEU C CB  1 
ATOM   3002 C CG  . LEU C 3  12  ? -0.76593  -0.28878  57.10639  1.000 54.85978 ? 11  LEU C CG  1 
ATOM   3003 C CD1 . LEU C 3  12  ? -1.82797  -0.49862  58.17294  1.000 55.66237 ? 11  LEU C CD1 1 
ATOM   3004 C CD2 . LEU C 3  12  ? -0.41152  1.18623   56.98156  1.000 59.70311 ? 11  LEU C CD2 1 
ATOM   3005 N N   . PRO C 3  13  ? 3.53759   -0.24570  58.47269  1.000 51.47450 ? 12  PRO C N   1 
ATOM   3006 C CA  . PRO C 3  13  ? 4.65882   -0.59800  59.35596  1.000 52.56283 ? 12  PRO C CA  1 
ATOM   3007 C C   . PRO C 3  13  ? 4.31488   -1.73643  60.31319  1.000 55.42139 ? 12  PRO C C   1 
ATOM   3008 O O   . PRO C 3  13  ? 5.12136   -2.65577  60.45716  1.000 53.90715 ? 12  PRO C O   1 
ATOM   3009 C CB  . PRO C 3  13  ? 4.93717   0.69132   60.14074  1.000 54.46994 ? 12  PRO C CB  1 
ATOM   3010 C CG  . PRO C 3  13  ? 4.08271   1.74877   59.56250  1.000 53.82162 ? 12  PRO C CG  1 
ATOM   3011 C CD  . PRO C 3  13  ? 3.18984   1.18494   58.51439  1.000 50.20346 ? 12  PRO C CD  1 
ATOM   3012 N N   . ARG D 4  3   ? -2.50580  -34.55167 56.26220  1.000 48.65840 ? 1   ARG D N   1 
ATOM   3013 C CA  . ARG D 4  3   ? -3.90550  -34.14473 56.31746  1.000 55.64461 ? 1   ARG D CA  1 
ATOM   3014 C C   . ARG D 4  3   ? -4.34440  -33.48851 55.01227  1.000 53.18769 ? 1   ARG D C   1 
ATOM   3015 O O   . ARG D 4  3   ? -3.51378  -33.13285 54.17499  1.000 47.93887 ? 1   ARG D O   1 
ATOM   3016 C CB  . ARG D 4  3   ? -4.14005  -33.18268 57.48568  1.000 46.59996 ? 1   ARG D CB  1 
ATOM   3017 C CG  . ARG D 4  3   ? -3.29502  -31.91680 57.42722  1.000 47.01484 ? 1   ARG D CG  1 
ATOM   3018 C CD  . ARG D 4  3   ? -3.86998  -30.81982 58.31398  1.000 49.89515 ? 1   ARG D CD  1 
ATOM   3019 N NE  . ARG D 4  3   ? -5.03980  -30.18962 57.71261  1.000 41.28928 ? 1   ARG D NE  1 
ATOM   3020 C CZ  . ARG D 4  3   ? -5.79585  -29.27975 58.31245  1.000 37.16329 ? 1   ARG D CZ  1 
ATOM   3021 N NH1 . ARG D 4  3   ? -5.54347  -28.87442 59.54639  1.000 32.49727 ? 1   ARG D NH1 1 
ATOM   3022 N NH2 . ARG D 4  3   ? -6.83069  -28.76238 57.65676  1.000 31.50981 ? 1   ARG D NH2 1 
ATOM   3023 N N   . LYS D 4  4   ? -5.65552  -33.33651 54.84261  1.000 41.75183 ? 2   LYS D N   1 
ATOM   3024 C CA  . LYS D 4  4   ? -6.17646  -32.58432 53.71347  1.000 38.48342 ? 2   LYS D CA  1 
ATOM   3025 C C   . LYS D 4  4   ? -5.94730  -31.09130 53.92846  1.000 32.43197 ? 2   LYS D C   1 
ATOM   3026 O O   . LYS D 4  4   ? -5.76771  -30.61809 55.05371  1.000 33.17588 ? 2   LYS D O   1 
ATOM   3027 C CB  . LYS D 4  4   ? -7.66799  -32.86085 53.51908  1.000 44.61843 ? 2   LYS D CB  1 
ATOM   3028 C CG  . LYS D 4  4   ? -7.98701  -34.24718 52.98642  1.000 50.68841 ? 2   LYS D CG  1 
ATOM   3029 C CD  . LYS D 4  4   ? -9.48832  -34.49436 52.96678  1.000 47.57012 ? 2   LYS D CD  1 
ATOM   3030 C CE  . LYS D 4  4   ? -10.02694 -34.51739 51.54497  1.000 53.94264 ? 2   LYS D CE  1 
ATOM   3031 N NZ  . LYS D 4  4   ? -10.15816 -33.14706 50.97523  1.000 62.35496 ? 2   LYS D NZ  1 
ATOM   3032 N N   . GLU D 4  5   ? -5.95385  -30.34294 52.82389  1.000 32.60724 ? 3   GLU D N   1 
ATOM   3033 C CA  . GLU D 4  5   ? -5.76244  -28.89973 52.92100  1.000 31.23677 ? 3   GLU D CA  1 
ATOM   3034 C C   . GLU D 4  5   ? -6.90732  -28.24141 53.68113  1.000 29.67304 ? 3   GLU D C   1 
ATOM   3035 O O   . GLU D 4  5   ? -6.69211  -27.28481 54.43351  1.000 26.68747 ? 3   GLU D O   1 
ATOM   3036 C CB  . GLU D 4  5   ? -5.62225  -28.28939 51.52673  1.000 27.18941 ? 3   GLU D CB  1 
ATOM   3037 C CG  . GLU D 4  5   ? -4.50802  -27.25996 51.42409  1.000 48.45845 ? 3   GLU D CG  1 
ATOM   3038 C CD  . GLU D 4  5   ? -4.46445  -26.57377 50.07371  1.000 63.13259 ? 3   GLU D CD  1 
ATOM   3039 O OE1 . GLU D 4  5   ? -4.37785  -27.28091 49.04681  1.000 59.34050 ? 3   GLU D OE1 1 
ATOM   3040 O OE2 . GLU D 4  5   ? -4.51434  -25.32548 50.04070  1.000 61.34073 ? 3   GLU D OE2 1 
ATOM   3041 N N   . VAL D 4  6   ? -8.12894  -28.73939 53.49838  1.000 20.92489 ? 4   VAL D N   1 
ATOM   3042 C CA  . VAL D 4  6   ? -9.31204  -28.22810 54.18129  1.000 23.10922 ? 4   VAL D CA  1 
ATOM   3043 C C   . VAL D 4  6   ? -9.99826  -29.40414 54.86094  1.000 24.68844 ? 4   VAL D C   1 
ATOM   3044 O O   . VAL D 4  6   ? -10.35743 -30.38369 54.19635  1.000 25.00147 ? 4   VAL D O   1 
ATOM   3045 C CB  . VAL D 4  6   ? -10.27710 -27.52075 53.21468  1.000 21.57555 ? 4   VAL D CB  1 
ATOM   3046 C CG1 . VAL D 4  6   ? -11.58158 -27.17499 53.92019  1.000 17.67595 ? 4   VAL D CG1 1 
ATOM   3047 C CG2 . VAL D 4  6   ? -9.62833  -26.27358 52.63652  1.000 27.09388 ? 4   VAL D CG2 1 
ATOM   3048 N N   . GLU D 4  7   ? -10.17951 -29.31116 56.17703  1.000 25.22971 ? 5   GLU D N   1 
ATOM   3049 C CA  . GLU D 4  7   ? -10.74742 -30.39177 56.97328  1.000 21.92002 ? 5   GLU D CA  1 
ATOM   3050 C C   . GLU D 4  7   ? -11.96791 -29.88245 57.72547  1.000 21.88623 ? 5   GLU D C   1 
ATOM   3051 O O   . GLU D 4  7   ? -11.92197 -28.81008 58.33753  1.000 22.14525 ? 5   GLU D O   1 
ATOM   3052 C CB  . GLU D 4  7   ? -9.71518  -30.95295 57.95630  1.000 24.60036 ? 5   GLU D CB  1 
ATOM   3053 C CG  . GLU D 4  7   ? -8.54323  -31.66914 57.29337  1.000 42.33572 ? 5   GLU D CG  1 
ATOM   3054 C CD  . GLU D 4  7   ? -8.86072  -33.10861 56.93010  1.000 51.74487 ? 5   GLU D CD  1 
ATOM   3055 O OE1 . GLU D 4  7   ? -10.03766 -33.51025 57.04881  1.000 56.77376 ? 5   GLU D OE1 1 
ATOM   3056 O OE2 . GLU D 4  7   ? -7.93041  -33.84116 56.53065  1.000 53.23161 ? 5   GLU D OE2 1 
ATOM   3057 N N   . GLN D 4  8   ? -13.04893 -30.65965 57.69132  1.000 22.13443 ? 6   GLN D N   1 
ATOM   3058 C CA  . GLN D 4  8   ? -14.32299 -30.26787 58.27545  1.000 22.59313 ? 6   GLN D CA  1 
ATOM   3059 C C   . GLN D 4  8   ? -14.81102 -31.34486 59.23426  1.000 27.40818 ? 6   GLN D C   1 
ATOM   3060 O O   . GLN D 4  8   ? -14.29718 -32.46559 59.26106  1.000 28.21608 ? 6   GLN D O   1 
ATOM   3061 C CB  . GLN D 4  8   ? -15.38260 -30.02550 57.19215  1.000 19.65208 ? 6   GLN D CB  1 
ATOM   3062 C CG  . GLN D 4  8   ? -15.17369 -28.76371 56.38313  1.000 25.49605 ? 6   GLN D CG  1 
ATOM   3063 C CD  . GLN D 4  8   ? -16.35273 -28.46086 55.48723  1.000 26.16240 ? 6   GLN D CD  1 
ATOM   3064 O OE1 . GLN D 4  8   ? -16.24885 -28.51401 54.26022  1.000 22.61848 ? 6   GLN D OE1 1 
ATOM   3065 N NE2 . GLN D 4  8   ? -17.49060 -28.14867 56.09834  1.000 18.90603 ? 6   GLN D NE2 1 
ATOM   3066 N N   . ASP D 4  9   ? -15.82501 -30.98728 60.01862  1.000 30.40725 ? 7   ASP D N   1 
ATOM   3067 C CA  . ASP D 4  9   ? -16.49069 -31.95395 60.87907  1.000 27.43438 ? 7   ASP D CA  1 
ATOM   3068 C C   . ASP D 4  9   ? -16.98844 -33.13213 60.04532  1.000 30.06932 ? 7   ASP D C   1 
ATOM   3069 O O   . ASP D 4  9   ? -17.65908 -32.92549 59.02490  1.000 25.57380 ? 7   ASP D O   1 
ATOM   3070 C CB  . ASP D 4  9   ? -17.65661 -31.29509 61.62068  1.000 29.41792 ? 7   ASP D CB  1 
ATOM   3071 C CG  . ASP D 4  9   ? -17.20412 -30.20917 62.58472  1.000 31.50524 ? 7   ASP D CG  1 
ATOM   3072 O OD1 . ASP D 4  9   ? -16.42805 -30.52079 63.51267  1.000 40.85926 ? 7   ASP D OD1 1 
ATOM   3073 O OD2 . ASP D 4  9   ? -17.62586 -29.04546 62.42012  1.000 32.46701 ? 7   ASP D OD2 1 
ATOM   3074 N N   . PRO D 4  10  ? -16.67871 -34.36646 60.43378  1.000 37.10228 ? 8   PRO D N   1 
ATOM   3075 C CA  . PRO D 4  10  ? -17.00753 -35.52844 59.58419  1.000 34.25052 ? 8   PRO D CA  1 
ATOM   3076 C C   . PRO D 4  10  ? -18.48325 -35.90706 59.57794  1.000 47.96631 ? 8   PRO D C   1 
ATOM   3077 O O   . PRO D 4  10  ? -19.24334 -35.45162 58.72008  1.000 39.71968 ? 8   PRO D O   1 
ATOM   3078 C CB  . PRO D 4  10  ? -16.16329 -36.66757 60.18900  1.000 42.55038 ? 8   PRO D CB  1 
ATOM   3079 C CG  . PRO D 4  10  ? -15.66048 -36.17392 61.49560  1.000 46.55114 ? 8   PRO D CG  1 
ATOM   3080 C CD  . PRO D 4  10  ? -15.74703 -34.69301 61.53363  1.000 39.10088 ? 8   PRO D CD  1 
ATOM   3081 N N   . GLY D 4  11  ? -18.88359 -36.75809 60.52504  1.000 62.60347 ? 9   GLY D N   1 
ATOM   3082 C CA  . GLY D 4  11  ? -20.19313 -37.37336 60.52713  1.000 40.36792 ? 9   GLY D CA  1 
ATOM   3083 C C   . GLY D 4  11  ? -21.34580 -36.39006 60.55350  1.000 38.95436 ? 9   GLY D C   1 
ATOM   3084 O O   . GLY D 4  11  ? -21.16621 -35.19084 60.78895  1.000 41.57807 ? 9   GLY D O   1 
ATOM   3085 N N   . PRO D 4  12  ? -22.56015 -36.88682 60.31874  1.000 36.79243 ? 10  PRO D N   1 
ATOM   3086 C CA  . PRO D 4  12  ? -23.71532 -35.98898 60.20996  1.000 30.53866 ? 10  PRO D CA  1 
ATOM   3087 C C   . PRO D 4  12  ? -24.06889 -35.34228 61.53987  1.000 28.64809 ? 10  PRO D C   1 
ATOM   3088 O O   . PRO D 4  12  ? -23.88560 -35.92159 62.61345  1.000 29.97145 ? 10  PRO D O   1 
ATOM   3089 C CB  . PRO D 4  12  ? -24.84480 -36.91251 59.73047  1.000 31.43059 ? 10  PRO D CB  1 
ATOM   3090 C CG  . PRO D 4  12  ? -24.17018 -38.17512 59.27413  1.000 38.99728 ? 10  PRO D CG  1 
ATOM   3091 C CD  . PRO D 4  12  ? -22.93411 -38.29333 60.10236  1.000 34.14926 ? 10  PRO D CD  1 
ATOM   3092 N N   . PHE D 4  13  ? -24.58427 -34.11686 61.45078  1.000 24.21465 ? 11  PHE D N   1 
ATOM   3093 C CA  . PHE D 4  13  ? -25.09262 -33.37885 62.60293  1.000 25.60959 ? 11  PHE D CA  1 
ATOM   3094 C C   . PHE D 4  13  ? -26.60805 -33.55684 62.64912  1.000 28.04302 ? 11  PHE D C   1 
ATOM   3095 O O   . PHE D 4  13  ? -27.31713 -33.11434 61.73874  1.000 21.98799 ? 11  PHE D O   1 
ATOM   3096 C CB  . PHE D 4  13  ? -24.73031 -31.89643 62.51097  1.000 26.61357 ? 11  PHE D CB  1 
ATOM   3097 C CG  . PHE D 4  13  ? -23.29299 -31.58584 62.83952  1.000 25.61799 ? 11  PHE D CG  1 
ATOM   3098 C CD1 . PHE D 4  13  ? -22.42443 -32.57620 63.26752  1.000 19.80075 ? 11  PHE D CD1 1 
ATOM   3099 C CD2 . PHE D 4  13  ? -22.81576 -30.28893 62.72306  1.000 21.78670 ? 11  PHE D CD2 1 
ATOM   3100 C CE1 . PHE D 4  13  ? -21.10441 -32.27774 63.56830  1.000 30.09491 ? 11  PHE D CE1 1 
ATOM   3101 C CE2 . PHE D 4  13  ? -21.50070 -29.98402 63.02282  1.000 23.28752 ? 11  PHE D CE2 1 
ATOM   3102 C CZ  . PHE D 4  13  ? -20.64357 -30.97930 63.44594  1.000 22.48997 ? 11  PHE D CZ  1 
ATOM   3103 N N   . ASN D 4  14  ? -27.10411 -34.20500 63.70311  1.000 23.04453 ? 12  ASN D N   1 
ATOM   3104 C CA  . ASN D 4  14  ? -28.53935 -34.35564 63.93147  1.000 27.18409 ? 12  ASN D CA  1 
ATOM   3105 C C   . ASN D 4  14  ? -28.94980 -33.38666 65.03419  1.000 27.30674 ? 12  ASN D C   1 
ATOM   3106 O O   . ASN D 4  14  ? -28.65004 -33.61048 66.21068  1.000 23.28988 ? 12  ASN D O   1 
ATOM   3107 C CB  . ASN D 4  14  ? -28.89490 -35.79505 64.29632  1.000 27.66874 ? 12  ASN D CB  1 
ATOM   3108 C CG  . ASN D 4  14  ? -28.69132 -36.75486 63.14074  1.000 32.30111 ? 12  ASN D CG  1 
ATOM   3109 O OD1 . ASN D 4  14  ? -29.46240 -36.75846 62.18125  1.000 38.48684 ? 12  ASN D OD1 1 
ATOM   3110 N ND2 . ASN D 4  14  ? -27.65693 -37.58058 63.23059  1.000 34.78528 ? 12  ASN D ND2 1 
ATOM   3111 N N   . VAL D 4  15  ? -29.64141 -32.31825 64.65248  1.000 22.54424 ? 13  VAL D N   1 
ATOM   3112 C CA  . VAL D 4  15  ? -29.89790 -31.19598 65.55118  1.000 23.01158 ? 13  VAL D CA  1 
ATOM   3113 C C   . VAL D 4  15  ? -31.40227 -30.96458 65.64996  1.000 27.11209 ? 13  VAL D C   1 
ATOM   3114 O O   . VAL D 4  15  ? -32.09970 -30.98738 64.62524  1.000 23.15302 ? 13  VAL D O   1 
ATOM   3115 C CB  . VAL D 4  15  ? -29.15934 -29.93712 65.06347  1.000 30.51619 ? 13  VAL D CB  1 
ATOM   3116 C CG1 . VAL D 4  15  ? -29.76299 -28.67456 65.65388  1.000 26.46562 ? 13  VAL D CG1 1 
ATOM   3117 C CG2 . VAL D 4  15  ? -27.67313 -30.03323 65.38907  1.000 28.38566 ? 13  VAL D CG2 1 
ATOM   3118 N N   . PRO D 4  16  ? -31.94972 -30.74840 66.84492  1.000 22.45388 ? 14  PRO D N   1 
ATOM   3119 C CA  . PRO D 4  16  ? -33.38094 -30.44523 66.94697  1.000 21.25237 ? 14  PRO D CA  1 
ATOM   3120 C C   . PRO D 4  16  ? -33.67773 -29.02408 66.49464  1.000 26.55922 ? 14  PRO D C   1 
ATOM   3121 O O   . PRO D 4  16  ? -32.87845 -28.10446 66.69209  1.000 21.58729 ? 14  PRO D O   1 
ATOM   3122 C CB  . PRO D 4  16  ? -33.69093 -30.63346 68.43942  1.000 25.80809 ? 14  PRO D CB  1 
ATOM   3123 C CG  . PRO D 4  16  ? -32.37804 -30.73787 69.13948  1.000 23.73682 ? 14  PRO D CG  1 
ATOM   3124 C CD  . PRO D 4  16  ? -31.26257 -30.69798 68.14629  1.000 24.91179 ? 14  PRO D CD  1 
ATOM   3125 N N   . GLU D 4  17  ? -34.84244 -28.86319 65.86799  1.000 20.46270 ? 15  GLU D N   1 
ATOM   3126 C CA  . GLU D 4  17  ? -35.29237 -27.56514 65.38057  1.000 20.30277 ? 15  GLU D CA  1 
ATOM   3127 C C   . GLU D 4  17  ? -35.27502 -26.52746 66.49683  1.000 25.91082 ? 15  GLU D C   1 
ATOM   3128 O O   . GLU D 4  17  ? -35.77174 -26.77369 67.59879  1.000 21.74794 ? 15  GLU D O   1 
ATOM   3129 C CB  . GLU D 4  17  ? -36.70346 -27.70509 64.80244  1.000 23.07007 ? 15  GLU D CB  1 
ATOM   3130 C CG  . GLU D 4  17  ? -37.29772 -26.43684 64.22587  1.000 31.29094 ? 15  GLU D CG  1 
ATOM   3131 C CD  . GLU D 4  17  ? -38.70152 -26.65612 63.68290  1.000 47.60446 ? 15  GLU D CD  1 
ATOM   3132 O OE1 . GLU D 4  17  ? -39.24707 -27.76486 63.86781  1.000 43.13263 ? 15  GLU D OE1 1 
ATOM   3133 O OE2 . GLU D 4  17  ? -39.25885 -25.72251 63.06811  1.000 43.27443 ? 15  GLU D OE2 1 
ATOM   3134 N N   . GLY D 4  18  ? -34.69359 -25.36330 66.20509  1.000 20.25395 ? 16  GLY D N   1 
ATOM   3135 C CA  . GLY D 4  18  ? -34.56593 -24.29250 67.17101  1.000 18.70735 ? 16  GLY D CA  1 
ATOM   3136 C C   . GLY D 4  18  ? -33.23125 -24.23360 67.88674  1.000 20.66062 ? 16  GLY D C   1 
ATOM   3137 O O   . GLY D 4  18  ? -32.93783 -23.21913 68.53222  1.000 18.93365 ? 16  GLY D O   1 
ATOM   3138 N N   . ALA D 4  19  ? -32.41745 -25.28022 67.79265  1.000 17.78496 ? 17  ALA D N   1 
ATOM   3139 C CA  . ALA D 4  19  ? -31.12120 -25.28524 68.45005  1.000 25.60064 ? 17  ALA D CA  1 
ATOM   3140 C C   . ALA D 4  19  ? -30.07689 -24.56216 67.60314  1.000 20.99926 ? 17  ALA D C   1 
ATOM   3141 O O   . ALA D 4  19  ? -30.21819 -24.40459 66.38787  1.000 17.64237 ? 17  ALA D O   1 
ATOM   3142 C CB  . ALA D 4  19  ? -30.66312 -26.71667 68.73042  1.000 22.95951 ? 17  ALA D CB  1 
ATOM   3143 N N   . THR D 4  20  ? -29.01622 -24.11851 68.27106  1.000 20.47883 ? 18  THR D N   1 
ATOM   3144 C CA  . THR D 4  20  ? -27.87863 -23.49405 67.61159  1.000 16.54904 ? 18  THR D CA  1 
ATOM   3145 C C   . THR D 4  20  ? -26.83758 -24.55628 67.28085  1.000 23.24073 ? 18  THR D C   1 
ATOM   3146 O O   . THR D 4  20  ? -26.55519 -25.43971 68.09536  1.000 21.88760 ? 18  THR D O   1 
ATOM   3147 C CB  . THR D 4  20  ? -27.26757 -22.40976 68.50374  1.000 25.07587 ? 18  THR D CB  1 
ATOM   3148 O OG1 . THR D 4  20  ? -28.21003 -21.34378 68.67732  1.000 24.18569 ? 18  THR D OG1 1 
ATOM   3149 C CG2 . THR D 4  20  ? -25.99175 -21.85045 67.88764  1.000 22.20162 ? 18  THR D CG2 1 
ATOM   3150 N N   . VAL D 4  21  ? -26.27741 -24.47255 66.07582  1.000 20.01823 ? 19  VAL D N   1 
ATOM   3151 C CA  . VAL D 4  21  ? -25.32371 -25.45357 65.57373  1.000 21.25700 ? 19  VAL D CA  1 
ATOM   3152 C C   . VAL D 4  21  ? -24.03703 -24.73759 65.18394  1.000 21.37941 ? 19  VAL D C   1 
ATOM   3153 O O   . VAL D 4  21  ? -24.07251 -23.64870 64.60004  1.000 24.52456 ? 19  VAL D O   1 
ATOM   3154 C CB  . VAL D 4  21  ? -25.91177 -26.24142 64.38198  1.000 20.46422 ? 19  VAL D CB  1 
ATOM   3155 C CG1 . VAL D 4  21  ? -26.54269 -25.29516 63.38198  1.000 22.83260 ? 19  VAL D CG1 1 
ATOM   3156 C CG2 . VAL D 4  21  ? -24.84496 -27.10239 63.71337  1.000 21.75841 ? 19  VAL D CG2 1 
ATOM   3157 N N   . ALA D 4  22  ? -22.90063 -25.34881 65.51574  1.000 18.28640 ? 20  ALA D N   1 
ATOM   3158 C CA  . ALA D 4  22  ? -21.58384 -24.79113 65.22913  1.000 21.28002 ? 20  ALA D CA  1 
ATOM   3159 C C   . ALA D 4  22  ? -20.83721 -25.72218 64.28550  1.000 22.02289 ? 20  ALA D C   1 
ATOM   3160 O O   . ALA D 4  22  ? -20.64863 -26.90326 64.59558  1.000 23.03710 ? 20  ALA D O   1 
ATOM   3161 C CB  . ALA D 4  22  ? -20.78195 -24.58560 66.51634  1.000 23.96495 ? 20  ALA D CB  1 
ATOM   3162 N N   . PHE D 4  23  ? -20.41592 -25.19158 63.14073  1.000 15.73395 ? 21  PHE D N   1 
ATOM   3163 C CA  . PHE D 4  23  ? -19.56143 -25.90973 62.20677  1.000 17.01438 ? 21  PHE D CA  1 
ATOM   3164 C C   . PHE D 4  23  ? -18.12810 -25.42861 62.36990  1.000 16.33505 ? 21  PHE D C   1 
ATOM   3165 O O   . PHE D 4  23  ? -17.88532 -24.23863 62.58800  1.000 17.94354 ? 21  PHE D O   1 
ATOM   3166 C CB  . PHE D 4  23  ? -19.99987 -25.69506 60.75522  1.000 13.35608 ? 21  PHE D CB  1 
ATOM   3167 C CG  . PHE D 4  23  ? -21.40977 -26.12042 60.46467  1.000 17.75159 ? 21  PHE D CG  1 
ATOM   3168 C CD1 . PHE D 4  23  ? -22.46713 -25.24981 60.66761  1.000 17.48994 ? 21  PHE D CD1 1 
ATOM   3169 C CD2 . PHE D 4  23  ? -21.67522 -27.38263 59.95774  1.000 19.23720 ? 21  PHE D CD2 1 
ATOM   3170 C CE1 . PHE D 4  23  ? -23.76584 -25.63490 60.38185  1.000 17.89991 ? 21  PHE D CE1 1 
ATOM   3171 C CE2 . PHE D 4  23  ? -22.97213 -27.77333 59.67204  1.000 21.77743 ? 21  PHE D CE2 1 
ATOM   3172 C CZ  . PHE D 4  23  ? -24.01823 -26.89706 59.88442  1.000 14.42344 ? 21  PHE D CZ  1 
ATOM   3173 N N   . ASN D 4  24  ? -17.17966 -26.35074 62.24822  1.000 12.50322 ? 22  ASN D N   1 
ATOM   3174 C CA  . ASN D 4  24  ? -15.77081 -26.01197 62.35819  1.000 20.72965 ? 22  ASN D CA  1 
ATOM   3175 C C   . ASN D 4  24  ? -15.00839 -26.52788 61.14967  1.000 22.91787 ? 22  ASN D C   1 
ATOM   3176 O O   . ASN D 4  24  ? -15.33191 -27.57686 60.58607  1.000 21.42085 ? 22  ASN D O   1 
ATOM   3177 C CB  . ASN D 4  24  ? -15.16233 -26.56803 63.64148  1.000 17.24824 ? 22  ASN D CB  1 
ATOM   3178 C CG  . ASN D 4  24  ? -15.67189 -25.85323 64.86582  1.000 21.34454 ? 22  ASN D CG  1 
ATOM   3179 O OD1 . ASN D 4  24  ? -16.57671 -26.33360 65.54901  1.000 25.88813 ? 22  ASN D OD1 1 
ATOM   3180 N ND2 . ASN D 4  24  ? -15.11543 -24.67830 65.13427  1.000 15.76611 ? 22  ASN D ND2 1 
ATOM   3181 N N   . CYS D 4  25  ? -13.98477 -25.76996 60.76670  1.000 19.22717 ? 23  CYS D N   1 
ATOM   3182 C CA  . CYS D 4  25  ? -13.16898 -26.07306 59.60339  1.000 20.98713 ? 23  CYS D CA  1 
ATOM   3183 C C   . CYS D 4  25  ? -11.76372 -25.54459 59.85262  1.000 17.24688 ? 23  CYS D C   1 
ATOM   3184 O O   . CYS D 4  25  ? -11.59674 -24.45458 60.40693  1.000 21.26993 ? 23  CYS D O   1 
ATOM   3185 C CB  . CYS D 4  25  ? -13.77604 -25.45052 58.33793  1.000 19.85194 ? 23  CYS D CB  1 
ATOM   3186 S SG  . CYS D 4  25  ? -12.70068 -25.41808 56.88320  1.000 23.97007 ? 23  CYS D SG  1 
ATOM   3187 N N   . THR D 4  26  ? -10.75891 -26.32531 59.46108  1.000 16.49253 ? 24  THR D N   1 
ATOM   3188 C CA  . THR D 4  26  ? -9.36725  -25.90919 59.56003  1.000 19.82851 ? 24  THR D CA  1 
ATOM   3189 C C   . THR D 4  26  ? -8.69503  -25.99670 58.19690  1.000 20.43150 ? 24  THR D C   1 
ATOM   3190 O O   . THR D 4  26  ? -9.01806  -26.86322 57.37824  1.000 23.35651 ? 24  THR D O   1 
ATOM   3191 C CB  . THR D 4  26  ? -8.57699  -26.76275 60.56422  1.000 23.04861 ? 24  THR D CB  1 
ATOM   3192 O OG1 . THR D 4  26  ? -8.60245  -28.13630 60.15512  1.000 27.19021 ? 24  THR D OG1 1 
ATOM   3193 C CG2 . THR D 4  26  ? -9.16033  -26.63091 61.96628  1.000 22.14221 ? 24  THR D CG2 1 
ATOM   3194 N N   . TYR D 4  27  ? -7.74718  -25.09114 57.96829  1.000 20.44077 ? 25  TYR D N   1 
ATOM   3195 C CA  . TYR D 4  27  ? -6.97109  -25.04943 56.73950  1.000 23.34198 ? 25  TYR D CA  1 
ATOM   3196 C C   . TYR D 4  27  ? -5.48905  -25.03677 57.08780  1.000 26.53532 ? 25  TYR D C   1 
ATOM   3197 O O   . TYR D 4  27  ? -5.08558  -24.50878 58.12775  1.000 22.19021 ? 25  TYR D O   1 
ATOM   3198 C CB  . TYR D 4  27  ? -7.33521  -23.82207 55.88850  1.000 18.64112 ? 25  TYR D CB  1 
ATOM   3199 C CG  . TYR D 4  27  ? -7.03875  -22.49947 56.56043  1.000 20.18119 ? 25  TYR D CG  1 
ATOM   3200 C CD1 . TYR D 4  27  ? -7.95397  -21.91755 57.42931  1.000 16.94863 ? 25  TYR D CD1 1 
ATOM   3201 C CD2 . TYR D 4  27  ? -5.84377  -21.83162 56.32466  1.000 17.97855 ? 25  TYR D CD2 1 
ATOM   3202 C CE1 . TYR D 4  27  ? -7.68538  -20.70869 58.04657  1.000 21.70261 ? 25  TYR D CE1 1 
ATOM   3203 C CE2 . TYR D 4  27  ? -5.56658  -20.62431 56.93613  1.000 19.84643 ? 25  TYR D CE2 1 
ATOM   3204 C CZ  . TYR D 4  27  ? -6.48926  -20.06697 57.79635  1.000 24.61628 ? 25  TYR D CZ  1 
ATOM   3205 O OH  . TYR D 4  27  ? -6.21233  -18.86399 58.40654  1.000 21.57594 ? 25  TYR D OH  1 
ATOM   3206 N N   . SER D 4  28  ? -4.67764  -25.62227 56.20759  1.000 24.17467 ? 26  SER D N   1 
ATOM   3207 C CA  . SER D 4  28  ? -3.25454  -25.79225 56.47946  1.000 33.52827 ? 26  SER D CA  1 
ATOM   3208 C C   . SER D 4  28  ? -2.38103  -24.68181 55.91165  1.000 22.04892 ? 26  SER D C   1 
ATOM   3209 O O   . SER D 4  28  ? -1.34051  -24.37257 56.50050  1.000 28.11136 ? 26  SER D O   1 
ATOM   3210 C CB  . SER D 4  28  ? -2.76508  -27.13879 55.93342  1.000 28.14556 ? 26  SER D CB  1 
ATOM   3211 O OG  . SER D 4  28  ? -3.27675  -27.38408 54.63608  1.000 38.74122 ? 26  SER D OG  1 
ATOM   3212 N N   . ASN D 4  29  ? -2.76726  -24.07140 54.79345  1.000 25.14035 ? 27  ASN D N   1 
ATOM   3213 C CA  . ASN D 4  29  ? -1.93652  -23.05578 54.15078  1.000 28.46425 ? 27  ASN D CA  1 
ATOM   3214 C C   . ASN D 4  29  ? -2.15125  -21.71592 54.84629  1.000 26.26522 ? 27  ASN D C   1 
ATOM   3215 O O   . ASN D 4  29  ? -3.20613  -21.09134 54.69468  1.000 25.45701 ? 27  ASN D O   1 
ATOM   3216 C CB  . ASN D 4  29  ? -2.26107  -22.96514 52.66206  1.000 27.81882 ? 27  ASN D CB  1 
ATOM   3217 C CG  . ASN D 4  29  ? -1.59279  -21.77894 51.98705  1.000 35.26895 ? 27  ASN D CG  1 
ATOM   3218 O OD1 . ASN D 4  29  ? -0.55402  -21.29072 52.43994  1.000 26.06304 ? 27  ASN D OD1 1 
ATOM   3219 N ND2 . ASN D 4  29  ? -2.18755  -21.31046 50.89322  1.000 32.86408 ? 27  ASN D ND2 1 
ATOM   3220 N N   . SER D 4  30  ? -1.13854  -21.26427 55.59344  1.000 22.32511 ? 28  SER D N   1 
ATOM   3221 C CA  . SER D 4  30  ? -1.23766  -20.01172 56.33678  1.000 21.76342 ? 28  SER D CA  1 
ATOM   3222 C C   . SER D 4  30  ? -1.39683  -18.79782 55.42957  1.000 26.28241 ? 28  SER D C   1 
ATOM   3223 O O   . SER D 4  30  ? -1.83917  -17.74310 55.89917  1.000 25.80943 ? 28  SER D O   1 
ATOM   3224 C CB  . SER D 4  30  ? -0.00168  -19.82739 57.22037  1.000 31.33136 ? 28  SER D CB  1 
ATOM   3225 O OG  . SER D 4  30  ? 0.38026   -21.04845 57.82824  1.000 38.05122 ? 28  SER D OG  1 
ATOM   3226 N N   . ALA D 4  31  ? -1.03775  -18.91361 54.15192  1.000 25.53352 ? 29  ALA D N   1 
ATOM   3227 C CA  . ALA D 4  31  ? -1.16097  -17.80488 53.21359  1.000 26.52630 ? 29  ALA D CA  1 
ATOM   3228 C C   . ALA D 4  31  ? -2.56574  -17.65465 52.64259  1.000 26.93460 ? 29  ALA D C   1 
ATOM   3229 O O   . ALA D 4  31  ? -2.79702  -16.72196 51.86555  1.000 23.75417 ? 29  ALA D O   1 
ATOM   3230 C CB  . ALA D 4  31  ? -0.16001  -17.97092 52.06796  1.000 23.21165 ? 29  ALA D CB  1 
ATOM   3231 N N   . SER D 4  32  ? -3.49457  -18.54260 52.99921  1.000 25.27938 ? 36  SER D N   1 
ATOM   3232 C CA  . SER D 4  32  ? -4.87021  -18.44942 52.52164  1.000 26.28943 ? 36  SER D CA  1 
ATOM   3233 C C   . SER D 4  32  ? -5.43623  -17.05903 52.77746  1.000 21.14489 ? 36  SER D C   1 
ATOM   3234 O O   . SER D 4  32  ? -5.30473  -16.51333 53.87607  1.000 23.30859 ? 36  SER D O   1 
ATOM   3235 C CB  . SER D 4  32  ? -5.73219  -19.50669 53.21230  1.000 19.12158 ? 36  SER D CB  1 
ATOM   3236 O OG  . SER D 4  32  ? -5.29771  -20.81383 52.87989  1.000 22.68916 ? 36  SER D OG  1 
ATOM   3237 N N   . GLN D 4  33  ? -6.06248  -16.48498 51.75170  1.000 23.03820 ? 37  GLN D N   1 
ATOM   3238 C CA  . GLN D 4  33  ? -6.48811  -15.09103 51.78893  1.000 21.05083 ? 37  GLN D CA  1 
ATOM   3239 C C   . GLN D 4  33  ? -7.97008  -14.91103 52.09132  1.000 20.75929 ? 37  GLN D C   1 
ATOM   3240 O O   . GLN D 4  33  ? -8.32597  -14.05135 52.90256  1.000 25.31266 ? 37  GLN D O   1 
ATOM   3241 C CB  . GLN D 4  33  ? -6.15686  -14.40368 50.46038  1.000 20.46953 ? 37  GLN D CB  1 
ATOM   3242 C CG  . GLN D 4  33  ? -6.35739  -12.89869 50.48591  1.000 21.32888 ? 37  GLN D CG  1 
ATOM   3243 C CD  . GLN D 4  33  ? -5.92723  -12.22436 49.19815  1.000 27.48304 ? 37  GLN D CD  1 
ATOM   3244 O OE1 . GLN D 4  33  ? -5.12371  -12.76401 48.43463  1.000 28.74438 ? 37  GLN D OE1 1 
ATOM   3245 N NE2 . GLN D 4  33  ? -6.46232  -11.03426 48.95009  1.000 28.00767 ? 37  GLN D NE2 1 
ATOM   3246 N N   . SER D 4  34  ? -8.84821  -15.68879 51.46127  1.000 21.13406 ? 38  SER D N   1 
ATOM   3247 C CA  . SER D 4  34  ? -10.28453 -15.50750 51.61369  1.000 20.17329 ? 38  SER D CA  1 
ATOM   3248 C C   . SER D 4  34  ? -10.95270 -16.83382 51.94304  1.000 21.99562 ? 38  SER D C   1 
ATOM   3249 O O   . SER D 4  34  ? -10.46290 -17.90564 51.57558  1.000 17.55780 ? 38  SER D O   1 
ATOM   3250 C CB  . SER D 4  34  ? -10.91051 -14.90632 50.35042  1.000 23.55715 ? 38  SER D CB  1 
ATOM   3251 O OG  . SER D 4  34  ? -10.41133 -13.60146 50.11688  1.000 29.18908 ? 38  SER D OG  1 
ATOM   3252 N N   . PHE D 4  35  ? -12.08865 -16.74350 52.63593  1.000 18.45977 ? 39  PHE D N   1 
ATOM   3253 C CA  . PHE D 4  35  ? -12.77945 -17.90449 53.17636  1.000 21.96552 ? 39  PHE D CA  1 
ATOM   3254 C C   . PHE D 4  35  ? -14.28136 -17.72210 53.01071  1.000 21.01108 ? 39  PHE D C   1 
ATOM   3255 O O   . PHE D 4  35  ? -14.80180 -16.61491 53.17461  1.000 22.11246 ? 39  PHE D O   1 
ATOM   3256 C CB  . PHE D 4  35  ? -12.41795 -18.11433 54.65596  1.000 16.78442 ? 39  PHE D CB  1 
ATOM   3257 C CG  . PHE D 4  35  ? -10.94285 -17.99529 54.93904  1.000 20.13218 ? 39  PHE D CG  1 
ATOM   3258 C CD1 . PHE D 4  35  ? -10.36937 -16.76262 55.21203  1.000 17.26708 ? 39  PHE D CD1 1 
ATOM   3259 C CD2 . PHE D 4  35  ? -10.12810 -19.11430 54.91505  1.000 20.77886 ? 39  PHE D CD2 1 
ATOM   3260 C CE1 . PHE D 4  35  ? -9.01279  -16.65074 55.45960  1.000 22.66318 ? 39  PHE D CE1 1 
ATOM   3261 C CE2 . PHE D 4  35  ? -8.77003  -19.00934 55.16696  1.000 25.52640 ? 39  PHE D CE2 1 
ATOM   3262 C CZ  . PHE D 4  35  ? -8.21280  -17.77573 55.43887  1.000 20.91694 ? 39  PHE D CZ  1 
ATOM   3263 N N   . PHE D 4  36  ? -14.97291 -18.81167 52.67856  1.000 18.12644 ? 40  PHE D N   1 
ATOM   3264 C CA  . PHE D 4  36  ? -16.39425 -18.76172 52.36707  1.000 19.80893 ? 40  PHE D CA  1 
ATOM   3265 C C   . PHE D 4  36  ? -17.07735 -20.02434 52.86686  1.000 22.97630 ? 40  PHE D C   1 
ATOM   3266 O O   . PHE D 4  36  ? -16.45327 -21.08205 52.98704  1.000 22.68384 ? 40  PHE D O   1 
ATOM   3267 C CB  . PHE D 4  36  ? -16.65014 -18.61986 50.85475  1.000 18.14901 ? 40  PHE D CB  1 
ATOM   3268 C CG  . PHE D 4  36  ? -15.84729 -17.53146 50.19821  1.000 19.07533 ? 40  PHE D CG  1 
ATOM   3269 C CD1 . PHE D 4  36  ? -14.55791 -17.77469 49.75206  1.000 20.03419 ? 40  PHE D CD1 1 
ATOM   3270 C CD2 . PHE D 4  36  ? -16.38264 -16.26544 50.02679  1.000 18.18378 ? 40  PHE D CD2 1 
ATOM   3271 C CE1 . PHE D 4  36  ? -13.81610 -16.77549 49.15447  1.000 23.42588 ? 40  PHE D CE1 1 
ATOM   3272 C CE2 . PHE D 4  36  ? -15.64598 -15.26150 49.42866  1.000 22.87981 ? 40  PHE D CE2 1 
ATOM   3273 C CZ  . PHE D 4  36  ? -14.36075 -15.51755 48.99053  1.000 24.52485 ? 40  PHE D CZ  1 
ATOM   3274 N N   . TRP D 4  37  ? -18.37086 -19.90094 53.15142  1.000 16.50273 ? 41  TRP D N   1 
ATOM   3275 C CA  . TRP D 4  37  ? -19.23245 -21.03998 53.42903  1.000 16.74289 ? 41  TRP D CA  1 
ATOM   3276 C C   . TRP D 4  37  ? -20.22708 -21.18948 52.28780  1.000 20.67571 ? 41  TRP D C   1 
ATOM   3277 O O   . TRP D 4  37  ? -20.83058 -20.20400 51.85147  1.000 18.51092 ? 41  TRP D O   1 
ATOM   3278 C CB  . TRP D 4  37  ? -19.97403 -20.87307 54.75859  1.000 17.21284 ? 41  TRP D CB  1 
ATOM   3279 C CG  . TRP D 4  37  ? -19.11237 -21.09982 55.96445  1.000 18.27132 ? 41  TRP D CG  1 
ATOM   3280 C CD1 . TRP D 4  37  ? -18.53187 -20.14519 56.74789  1.000 16.51106 ? 41  TRP D CD1 1 
ATOM   3281 C CD2 . TRP D 4  37  ? -18.73101 -22.36409 56.52348  1.000 17.72876 ? 41  TRP D CD2 1 
ATOM   3282 N NE1 . TRP D 4  37  ? -17.81317 -20.73610 57.75978  1.000 21.38201 ? 41  TRP D NE1 1 
ATOM   3283 C CE2 . TRP D 4  37  ? -17.91883 -22.09724 57.64373  1.000 18.11421 ? 41  TRP D CE2 1 
ATOM   3284 C CE3 . TRP D 4  37  ? -18.99827 -23.69459 56.18578  1.000 16.10768 ? 41  TRP D CE3 1 
ATOM   3285 C CZ2 . TRP D 4  37  ? -17.37411 -23.11129 58.43071  1.000 20.66075 ? 41  TRP D CZ2 1 
ATOM   3286 C CZ3 . TRP D 4  37  ? -18.45619 -24.69971 56.96810  1.000 16.49949 ? 41  TRP D CZ3 1 
ATOM   3287 C CH2 . TRP D 4  37  ? -17.65312 -24.40232 58.07647  1.000 19.78628 ? 41  TRP D CH2 1 
ATOM   3288 N N   . TYR D 4  38  ? -20.37712 -22.41344 51.79489  1.000 18.38507 ? 42  TYR D N   1 
ATOM   3289 C CA  . TYR D 4  38  ? -21.37775 -22.73946 50.79390  1.000 18.83946 ? 42  TYR D CA  1 
ATOM   3290 C C   . TYR D 4  38  ? -22.34264 -23.76354 51.36981  1.000 19.67115 ? 42  TYR D C   1 
ATOM   3291 O O   . TYR D 4  38  ? -21.99320 -24.53414 52.26891  1.000 19.11110 ? 42  TYR D O   1 
ATOM   3292 C CB  . TYR D 4  38  ? -20.74915 -23.29801 49.50846  1.000 18.89900 ? 42  TYR D CB  1 
ATOM   3293 C CG  . TYR D 4  38  ? -20.16737 -22.25755 48.57429  1.000 23.45115 ? 42  TYR D CG  1 
ATOM   3294 C CD1 . TYR D 4  38  ? -19.05782 -21.50747 48.94037  1.000 20.10644 ? 42  TYR D CD1 1 
ATOM   3295 C CD2 . TYR D 4  38  ? -20.71958 -22.03889 47.31795  1.000 19.91728 ? 42  TYR D CD2 1 
ATOM   3296 C CE1 . TYR D 4  38  ? -18.51791 -20.56291 48.08611  1.000 20.62233 ? 42  TYR D CE1 1 
ATOM   3297 C CE2 . TYR D 4  38  ? -20.18688 -21.09662 46.45594  1.000 23.45210 ? 42  TYR D CE2 1 
ATOM   3298 C CZ  . TYR D 4  38  ? -19.08613 -20.36208 46.84498  1.000 23.56678 ? 42  TYR D CZ  1 
ATOM   3299 O OH  . TYR D 4  38  ? -18.55226 -19.42248 45.99204  1.000 21.19555 ? 42  TYR D OH  1 
ATOM   3300 N N   . ARG D 4  39  ? -23.55773 -23.76382 50.83562  1.000 14.01216 ? 43  ARG D N   1 
ATOM   3301 C CA  . ARG D 4  39  ? -24.60526 -24.69428 51.22168  1.000 22.40674 ? 43  ARG D CA  1 
ATOM   3302 C C   . ARG D 4  39  ? -25.01606 -25.50585 49.99973  1.000 25.09647 ? 43  ARG D C   1 
ATOM   3303 O O   . ARG D 4  39  ? -25.13201 -24.96254 48.89645  1.000 20.44508 ? 43  ARG D O   1 
ATOM   3304 C CB  . ARG D 4  39  ? -25.80000 -23.93349 51.80258  1.000 24.20850 ? 43  ARG D CB  1 
ATOM   3305 C CG  . ARG D 4  39  ? -26.97773 -24.78760 52.18463  1.000 32.48903 ? 43  ARG D CG  1 
ATOM   3306 C CD  . ARG D 4  39  ? -28.24984 -23.96169 52.19643  1.000 26.10321 ? 43  ARG D CD  1 
ATOM   3307 N NE  . ARG D 4  39  ? -29.40490 -24.75298 51.79531  1.000 31.32864 ? 43  ARG D NE  1 
ATOM   3308 C CZ  . ARG D 4  39  ? -30.47613 -24.94458 52.55087  1.000 29.90762 ? 43  ARG D CZ  1 
ATOM   3309 N NH1 . ARG D 4  39  ? -30.58026 -24.39910 53.75159  1.000 28.39303 ? 43  ARG D NH1 1 
ATOM   3310 N NH2 . ARG D 4  39  ? -31.46764 -25.70157 52.09001  1.000 36.31232 ? 43  ARG D NH2 1 
ATOM   3311 N N   . GLN D 4  40  ? -25.22691 -26.80805 50.19052  1.000 23.69723 ? 44  GLN D N   1 
ATOM   3312 C CA  . GLN D 4  40  ? -25.48974 -27.71258 49.07537  1.000 23.63182 ? 44  GLN D CA  1 
ATOM   3313 C C   . GLN D 4  40  ? -26.54572 -28.73160 49.47349  1.000 26.52597 ? 44  GLN D C   1 
ATOM   3314 O O   . GLN D 4  40  ? -26.36189 -29.47264 50.44428  1.000 21.83120 ? 44  GLN D O   1 
ATOM   3315 C CB  . GLN D 4  40  ? -24.20563 -28.42141 48.63190  1.000 22.25862 ? 44  GLN D CB  1 
ATOM   3316 C CG  . GLN D 4  40  ? -24.41040 -29.46453 47.54179  1.000 25.10830 ? 44  GLN D CG  1 
ATOM   3317 C CD  . GLN D 4  40  ? -23.09811 -29.99954 46.99593  1.000 31.48277 ? 44  GLN D CD  1 
ATOM   3318 O OE1 . GLN D 4  40  ? -22.14287 -30.21398 47.74367  1.000 31.42610 ? 44  GLN D OE1 1 
ATOM   3319 N NE2 . GLN D 4  40  ? -23.04595 -30.21815 45.68654  1.000 22.74748 ? 44  GLN D NE2 1 
ATOM   3320 N N   . ASP D 4  41  ? -27.64002 -28.77343 48.71688  1.000 22.34434 ? 45  ASP D N   1 
ATOM   3321 C CA  . ASP D 4  41  ? -28.66340 -29.78838 48.90251  1.000 26.78248 ? 45  ASP D CA  1 
ATOM   3322 C C   . ASP D 4  41  ? -28.23770 -31.09828 48.24481  1.000 27.50046 ? 45  ASP D C   1 
ATOM   3323 O O   . ASP D 4  41  ? -27.36865 -31.13205 47.36899  1.000 25.03929 ? 45  ASP D O   1 
ATOM   3324 C CB  . ASP D 4  41  ? -29.99952 -29.32385 48.32036  1.000 31.42661 ? 45  ASP D CB  1 
ATOM   3325 C CG  . ASP D 4  41  ? -30.66278 -28.25239 49.16203  1.000 34.72709 ? 45  ASP D CG  1 
ATOM   3326 O OD1 . ASP D 4  41  ? -30.17043 -27.97617 50.27686  1.000 36.57804 ? 45  ASP D OD1 1 
ATOM   3327 O OD2 . ASP D 4  41  ? -31.67679 -27.68395 48.70577  1.000 42.62638 ? 45  ASP D OD2 1 
ATOM   3328 N N   . CYS D 4  42  ? -28.87321 -32.18559 48.67759  1.000 26.40020 ? 46  CYS D N   1 
ATOM   3329 C CA  . CYS D 4  42  ? -28.54292 -33.50910 48.16368  1.000 33.79973 ? 46  CYS D CA  1 
ATOM   3330 C C   . CYS D 4  42  ? -28.76991 -33.57853 46.65681  1.000 36.39636 ? 46  CYS D C   1 
ATOM   3331 O O   . CYS D 4  42  ? -29.83482 -33.20151 46.15826  1.000 28.17615 ? 46  CYS D O   1 
ATOM   3332 C CB  . CYS D 4  42  ? -29.38175 -34.56973 48.87823  1.000 34.56813 ? 46  CYS D CB  1 
ATOM   3333 S SG  . CYS D 4  42  ? -28.95425 -36.27706 48.46490  1.000 55.46228 ? 46  CYS D SG  1 
ATOM   3334 N N   . ARG D 4  43  ? -27.75133 -34.05348 45.93578  1.000 26.26523 ? 47  ARG D N   1 
ATOM   3335 C CA  . ARG D 4  43  ? -27.76597 -34.20759 44.47995  1.000 35.94116 ? 47  ARG D CA  1 
ATOM   3336 C C   . ARG D 4  43  ? -27.90954 -32.87635 43.74616  1.000 31.13636 ? 47  ARG D C   1 
ATOM   3337 O O   . ARG D 4  43  ? -28.22899 -32.85610 42.55335  1.000 32.90521 ? 47  ARG D O   1 
ATOM   3338 C CB  . ARG D 4  43  ? -28.86861 -35.17606 44.02780  1.000 34.55352 ? 47  ARG D CB  1 
ATOM   3339 C CG  . ARG D 4  43  ? -28.69321 -36.60236 44.52908  1.000 40.06694 ? 47  ARG D CG  1 
ATOM   3340 C CD  . ARG D 4  43  ? -29.94242 -37.43963 44.28323  1.000 37.77836 ? 47  ARG D CD  1 
ATOM   3341 N NE  . ARG D 4  43  ? -30.32571 -37.46182 42.87612  1.000 41.69637 ? 47  ARG D NE  1 
ATOM   3342 C CZ  . ARG D 4  43  ? -29.92719 -38.37807 42.00401  1.000 38.01563 ? 47  ARG D CZ  1 
ATOM   3343 N NH1 . ARG D 4  43  ? -29.12331 -39.36709 42.35886  1.000 38.61413 ? 47  ARG D NH1 1 
ATOM   3344 N NH2 . ARG D 4  43  ? -30.34609 -38.30027 40.74395  1.000 36.89915 ? 47  ARG D NH2 1 
ATOM   3345 N N   . LYS D 4  44  ? -27.67202 -31.75845 44.42359  1.000 32.93602 ? 48  LYS D N   1 
ATOM   3346 C CA  . LYS D 4  44  ? -27.82511 -30.43799 43.82647  1.000 27.79565 ? 48  LYS D CA  1 
ATOM   3347 C C   . LYS D 4  44  ? -26.47963 -29.70927 43.82764  1.000 27.22046 ? 48  LYS D C   1 
ATOM   3348 O O   . LYS D 4  44  ? -25.42748 -30.29442 44.10137  1.000 24.25722 ? 48  LYS D O   1 
ATOM   3349 C CB  . LYS D 4  44  ? -28.90545 -29.63892 44.55950  1.000 26.00036 ? 48  LYS D CB  1 
ATOM   3350 C CG  . LYS D 4  44  ? -30.27897 -29.69706 43.90330  1.000 38.69543 ? 48  LYS D CG  1 
ATOM   3351 C CD  . LYS D 4  44  ? -30.82954 -31.11573 43.88202  1.000 48.31045 ? 48  LYS D CD  1 
ATOM   3352 C CE  . LYS D 4  44  ? -32.26085 -31.15906 43.36863  1.000 55.87365 ? 48  LYS D CE  1 
ATOM   3353 N NZ  . LYS D 4  44  ? -33.05917 -29.99219 43.83587  1.000 61.65220 ? 48  LYS D NZ  1 
ATOM   3354 N N   . GLU D 4  45  ? -26.52475 -28.40778 43.51927  1.000 27.30546 ? 49  GLU D N   1 
ATOM   3355 C CA  . GLU D 4  45  ? -25.33119 -27.59791 43.34739  1.000 26.66204 ? 49  GLU D CA  1 
ATOM   3356 C C   . GLU D 4  45  ? -25.09357 -26.70901 44.56406  1.000 25.98760 ? 49  GLU D C   1 
ATOM   3357 O O   . GLU D 4  45  ? -26.03702 -26.35465 45.27910  1.000 23.73310 ? 49  GLU D O   1 
ATOM   3358 C CB  . GLU D 4  45  ? -25.45255 -26.72948 42.08922  1.000 21.11664 ? 49  GLU D CB  1 
ATOM   3359 C CG  . GLU D 4  45  ? -26.14472 -25.38977 42.30172  1.000 22.78867 ? 49  GLU D CG  1 
ATOM   3360 C CD  . GLU D 4  45  ? -27.65943 -25.48975 42.23857  1.000 34.09192 ? 49  GLU D CD  1 
ATOM   3361 O OE1 . GLU D 4  45  ? -28.18450 -26.61691 42.11647  1.000 28.68312 ? 49  GLU D OE1 1 
ATOM   3362 O OE2 . GLU D 4  45  ? -28.32600 -24.43620 42.31135  1.000 35.81140 ? 49  GLU D OE2 1 
ATOM   3363 N N   . PRO D 4  46  ? -23.83980 -26.34439 44.82792  1.000 20.70499 ? 50  PRO D N   1 
ATOM   3364 C CA  . PRO D 4  46  ? -23.55473 -25.46933 45.96894  1.000 21.99943 ? 50  PRO D CA  1 
ATOM   3365 C C   . PRO D 4  46  ? -23.99101 -24.03921 45.70029  1.000 23.14086 ? 50  PRO D C   1 
ATOM   3366 O O   . PRO D 4  46  ? -23.96558 -23.55623 44.56514  1.000 17.78445 ? 50  PRO D O   1 
ATOM   3367 C CB  . PRO D 4  46  ? -22.02912 -25.55942 46.12407  1.000 23.12834 ? 50  PRO D CB  1 
ATOM   3368 C CG  . PRO D 4  46  ? -21.58022 -26.65938 45.20699  1.000 20.75026 ? 50  PRO D CG  1 
ATOM   3369 C CD  . PRO D 4  46  ? -22.61191 -26.77498 44.14086  1.000 21.20207 ? 50  PRO D CD  1 
ATOM   3370 N N   . LYS D 4  47  ? -24.39512 -23.36014 46.77266  1.000 14.66512 ? 51  LYS D N   1 
ATOM   3371 C CA  . LYS D 4  47  ? -24.79051 -21.96053 46.71962  1.000 17.57493 ? 51  LYS D CA  1 
ATOM   3372 C C   . LYS D 4  47  ? -24.02584 -21.18559 47.78073  1.000 20.17164 ? 51  LYS D C   1 
ATOM   3373 O O   . LYS D 4  47  ? -23.90201 -21.63892 48.92214  1.000 20.53185 ? 51  LYS D O   1 
ATOM   3374 C CB  . LYS D 4  47  ? -26.30218 -21.78903 46.93452  1.000 23.17729 ? 51  LYS D CB  1 
ATOM   3375 C CG  . LYS D 4  47  ? -27.15587 -22.87929 46.30654  1.000 33.13605 ? 51  LYS D CG  1 
ATOM   3376 C CD  . LYS D 4  47  ? -28.55449 -22.37005 45.98893  1.000 40.19343 ? 51  LYS D CD  1 
ATOM   3377 C CE  . LYS D 4  47  ? -29.42053 -23.46455 45.38390  1.000 42.35514 ? 51  LYS D CE  1 
ATOM   3378 N NZ  . LYS D 4  47  ? -30.83446 -23.37383 45.84224  1.000 50.84635 ? 51  LYS D NZ  1 
ATOM   3379 N N   . LEU D 4  48  ? -23.51576 -20.01698 47.39847  1.000 19.86478 ? 52  LEU D N   1 
ATOM   3380 C CA  . LEU D 4  48  ? -22.75046 -19.19383 48.32525  1.000 23.15408 ? 52  LEU D CA  1 
ATOM   3381 C C   . LEU D 4  48  ? -23.62090 -18.75083 49.49451  1.000 22.89085 ? 52  LEU D C   1 
ATOM   3382 O O   . LEU D 4  48  ? -24.72843 -18.24025 49.30283  1.000 21.18845 ? 52  LEU D O   1 
ATOM   3383 C CB  . LEU D 4  48  ? -22.18277 -17.97507 47.59890  1.000 20.83285 ? 52  LEU D CB  1 
ATOM   3384 C CG  . LEU D 4  48  ? -21.47311 -16.94079 48.47464  1.000 24.69660 ? 52  LEU D CG  1 
ATOM   3385 C CD1 . LEU D 4  48  ? -20.14904 -17.48878 48.99091  1.000 16.79545 ? 52  LEU D CD1 1 
ATOM   3386 C CD2 . LEU D 4  48  ? -21.26386 -15.64250 47.70770  1.000 25.04502 ? 52  LEU D CD2 1 
ATOM   3387 N N   . LEU D 4  49  ? -23.11452 -18.94963 50.71207  1.000 24.64958 ? 53  LEU D N   1 
ATOM   3388 C CA  . LEU D 4  49  ? -23.82063 -18.54763 51.92428  1.000 21.59231 ? 53  LEU D CA  1 
ATOM   3389 C C   . LEU D 4  49  ? -23.28936 -17.22913 52.47975  1.000 27.97264 ? 53  LEU D C   1 
ATOM   3390 O O   . LEU D 4  49  ? -24.05324 -16.27387 52.64464  1.000 26.88874 ? 53  LEU D O   1 
ATOM   3391 C CB  . LEU D 4  49  ? -23.73183 -19.65605 52.98226  1.000 22.45917 ? 53  LEU D CB  1 
ATOM   3392 C CG  . LEU D 4  49  ? -24.66595 -19.50550 54.18478  1.000 28.14373 ? 53  LEU D CG  1 
ATOM   3393 C CD1 . LEU D 4  49  ? -26.09998 -19.84194 53.80028  1.000 24.54825 ? 53  LEU D CD1 1 
ATOM   3394 C CD2 . LEU D 4  49  ? -24.19814 -20.37451 55.34242  1.000 25.25496 ? 53  LEU D CD2 1 
ATOM   3395 N N   . MET D 4  50  ? -21.99117 -17.15373 52.76834  1.000 23.13797 ? 54  MET D N   1 
ATOM   3396 C CA  . MET D 4  50  ? -21.41721 -15.90887 53.26526  1.000 28.69243 ? 54  MET D CA  1 
ATOM   3397 C C   . MET D 4  50  ? -19.90114 -15.97453 53.16982  1.000 24.69283 ? 54  MET D C   1 
ATOM   3398 O O   . MET D 4  50  ? -19.30964 -17.05500 53.08498  1.000 22.76356 ? 54  MET D O   1 
ATOM   3399 C CB  . MET D 4  50  ? -21.82703 -15.63024 54.71490  1.000 29.71992 ? 54  MET D CB  1 
ATOM   3400 C CG  . MET D 4  50  ? -21.67553 -16.82500 55.63985  1.000 22.17042 ? 54  MET D CG  1 
ATOM   3401 S SD  . MET D 4  50  ? -22.66276 -16.65189 57.13464  1.000 37.52214 ? 54  MET D SD  1 
ATOM   3402 C CE  . MET D 4  50  ? -22.32510 -14.94709 57.56937  1.000 27.49005 ? 54  MET D CE  1 
ATOM   3403 N N   . SER D 4  51  ? -19.28394 -14.79651 53.19906  1.000 24.80813 ? 55  SER D N   1 
ATOM   3404 C CA  . SER D 4  51  ? -17.84535 -14.67912 53.36382  1.000 31.77665 ? 55  SER D CA  1 
ATOM   3405 C C   . SER D 4  51  ? -17.48641 -14.70076 54.84671  1.000 29.37110 ? 55  SER D C   1 
ATOM   3406 O O   . SER D 4  51  ? -18.31534 -14.42191 55.71726  1.000 31.82953 ? 55  SER D O   1 
ATOM   3407 C CB  . SER D 4  51  ? -17.32922 -13.39179 52.72073  1.000 33.54322 ? 55  SER D CB  1 
ATOM   3408 O OG  . SER D 4  51  ? -17.98030 -13.13585 51.49029  1.000 38.73156 ? 55  SER D OG  1 
ATOM   3409 N N   . VAL D 4  52  ? -16.22896 -15.03105 55.12949  1.000 29.38434 ? 56  VAL D N   1 
ATOM   3410 C CA  . VAL D 4  52  ? -15.73287 -15.16763 56.49506  1.000 30.71347 ? 56  VAL D CA  1 
ATOM   3411 C C   . VAL D 4  52  ? -14.72967 -14.05536 56.76479  1.000 38.21267 ? 56  VAL D C   1 
ATOM   3412 O O   . VAL D 4  52  ? -13.78413 -13.86224 55.99043  1.000 36.12517 ? 56  VAL D O   1 
ATOM   3413 C CB  . VAL D 4  52  ? -15.09686 -16.54881 56.72785  1.000 27.44108 ? 56  VAL D CB  1 
ATOM   3414 C CG1 . VAL D 4  52  ? -14.73126 -16.72165 58.19230  1.000 33.41492 ? 56  VAL D CG1 1 
ATOM   3415 C CG2 . VAL D 4  52  ? -16.04201 -17.65060 56.27799  1.000 22.07266 ? 56  VAL D CG2 1 
ATOM   3416 N N   . TYR D 4  53  ? -14.93053 -13.33258 57.86733  1.000 38.66727 ? 57  TYR D N   1 
ATOM   3417 C CA  . TYR D 4  53  ? -14.06600 -12.22771 58.25665  1.000 45.32917 ? 57  TYR D CA  1 
ATOM   3418 C C   . TYR D 4  53  ? -13.58602 -12.42457 59.68803  1.000 44.65575 ? 57  TYR D C   1 
ATOM   3419 O O   . TYR D 4  53  ? -14.24627 -13.08310 60.49708  1.000 36.89318 ? 57  TYR D O   1 
ATOM   3420 C CB  . TYR D 4  53  ? -14.78828 -10.87704 58.13203  1.000 47.42696 ? 57  TYR D CB  1 
ATOM   3421 C CG  . TYR D 4  53  ? -15.35868 -10.61261 56.75641  1.000 48.95883 ? 57  TYR D CG  1 
ATOM   3422 C CD1 . TYR D 4  53  ? -16.62801 -10.07074 56.60184  1.000 47.70141 ? 57  TYR D CD1 1 
ATOM   3423 C CD2 . TYR D 4  53  ? -14.62612 -10.90116 55.61217  1.000 48.99176 ? 57  TYR D CD2 1 
ATOM   3424 C CE1 . TYR D 4  53  ? -17.15305 -9.82722  55.34565  1.000 46.21584 ? 57  TYR D CE1 1 
ATOM   3425 C CE2 . TYR D 4  53  ? -15.14346 -10.66282 54.35240  1.000 47.98869 ? 57  TYR D CE2 1 
ATOM   3426 C CZ  . TYR D 4  53  ? -16.40687 -10.12531 54.22570  1.000 41.79902 ? 57  TYR D CZ  1 
ATOM   3427 O OH  . TYR D 4  53  ? -16.92493 -9.88457  52.97410  1.000 62.03384 ? 57  TYR D OH  1 
ATOM   3428 N N   . SER D 4  54  ? -12.42412 -11.83878 59.99293  1.000 41.39817 ? 58  SER D N   1 
ATOM   3429 C CA  . SER D 4  54  ? -11.85691 -11.96815 61.33249  1.000 44.65166 ? 58  SER D CA  1 
ATOM   3430 C C   . SER D 4  54  ? -12.77753 -11.36624 62.38662  1.000 46.08208 ? 58  SER D C   1 
ATOM   3431 O O   . SER D 4  54  ? -12.93559 -11.92820 63.47699  1.000 45.29624 ? 58  SER D O   1 
ATOM   3432 C CB  . SER D 4  54  ? -10.47918 -11.30813 61.38660  1.000 45.97953 ? 58  SER D CB  1 
ATOM   3433 O OG  . SER D 4  54  ? -9.45129  -12.25186 61.14137  1.000 46.66554 ? 58  SER D OG  1 
ATOM   3434 N N   . SER D 4  55  ? -13.39670 -10.22380 62.07908  1.000 49.68650 ? 63  SER D N   1 
ATOM   3435 C CA  . SER D 4  55  ? -14.30636 -9.58754  63.02443  1.000 48.91402 ? 63  SER D CA  1 
ATOM   3436 C C   . SER D 4  55  ? -15.55682 -10.41874 63.27536  1.000 49.15188 ? 63  SER D C   1 
ATOM   3437 O O   . SER D 4  55  ? -16.20352 -10.24462 64.31353  1.000 55.54407 ? 63  SER D O   1 
ATOM   3438 C CB  . SER D 4  55  ? -14.70190 -8.19854  62.52007  1.000 50.92300 ? 63  SER D CB  1 
ATOM   3439 O OG  . SER D 4  55  ? -14.91778 -8.20713  61.11871  1.000 53.80452 ? 63  SER D OG  1 
ATOM   3440 N N   . GLY D 4  56  ? -15.90783 -11.31481 62.35739  1.000 50.86582 ? 64  GLY D N   1 
ATOM   3441 C CA  . GLY D 4  56  ? -17.10403 -12.11778 62.50449  1.000 49.43763 ? 64  GLY D CA  1 
ATOM   3442 C C   . GLY D 4  56  ? -18.27125 -11.57415 61.70816  1.000 45.73706 ? 64  GLY D C   1 
ATOM   3443 O O   . GLY D 4  56  ? -19.01931 -10.72087 62.19512  1.000 55.17789 ? 64  GLY D O   1 
ATOM   3444 N N   . ASN D 4  57  ? -18.43400 -12.05797 60.47904  1.000 45.88583 ? 65  ASN D N   1 
ATOM   3445 C CA  . ASN D 4  57  ? -19.53282 -11.61562 59.63003  1.000 34.59482 ? 65  ASN D CA  1 
ATOM   3446 C C   . ASN D 4  57  ? -20.85388 -12.14479 60.17586  1.000 40.95837 ? 65  ASN D C   1 
ATOM   3447 O O   . ASN D 4  57  ? -21.04323 -13.36037 60.29147  1.000 32.42249 ? 65  ASN D O   1 
ATOM   3448 C CB  . ASN D 4  57  ? -19.31365 -12.09080 58.19586  1.000 38.87281 ? 65  ASN D CB  1 
ATOM   3449 C CG  . ASN D 4  57  ? -20.29336 -11.47067 57.21911  1.000 40.91330 ? 65  ASN D CG  1 
ATOM   3450 O OD1 . ASN D 4  57  ? -20.92466 -10.45496 57.51359  1.000 47.01723 ? 65  ASN D OD1 1 
ATOM   3451 N ND2 . ASN D 4  57  ? -20.42603 -12.08135 56.04762  1.000 40.32093 ? 65  ASN D ND2 1 
ATOM   3452 N N   . GLU D 4  58  ? -21.76270 -11.23539 60.51764  1.000 38.97661 ? 67  GLU D N   1 
ATOM   3453 C CA  . GLU D 4  58  ? -23.08799 -11.59035 61.00247  1.000 45.04075 ? 67  GLU D CA  1 
ATOM   3454 C C   . GLU D 4  58  ? -24.13692 -11.20408 59.96896  1.000 44.96373 ? 67  GLU D C   1 
ATOM   3455 O O   . GLU D 4  58  ? -24.09855 -10.10305 59.41027  1.000 46.33536 ? 67  GLU D O   1 
ATOM   3456 C CB  . GLU D 4  58  ? -23.39626 -10.90827 62.33882  1.000 44.85452 ? 67  GLU D CB  1 
ATOM   3457 C CG  . GLU D 4  58  ? -24.63197 -11.46472 63.03389  1.000 48.86250 ? 67  GLU D CG  1 
ATOM   3458 C CD  . GLU D 4  58  ? -24.82403 -10.90971 64.43329  1.000 57.96499 ? 67  GLU D CD  1 
ATOM   3459 O OE1 . GLU D 4  58  ? -23.88784 -11.02020 65.25232  1.000 64.12583 ? 67  GLU D OE1 1 
ATOM   3460 O OE2 . GLU D 4  58  ? -25.91459 -10.36959 64.71693  1.000 65.83200 ? 67  GLU D OE2 1 
ATOM   3461 N N   . ASP D 4  59  ? -25.07345 -12.11988 59.71909  1.000 36.36647 ? 68  ASP D N   1 
ATOM   3462 C CA  . ASP D 4  59  ? -26.14004 -11.89882 58.74062  1.000 38.85392 ? 68  ASP D CA  1 
ATOM   3463 C C   . ASP D 4  59  ? -27.34341 -12.72971 59.19188  1.000 31.74146 ? 68  ASP D C   1 
ATOM   3464 O O   . ASP D 4  59  ? -27.44749 -13.91677 58.87582  1.000 31.33109 ? 68  ASP D O   1 
ATOM   3465 C CB  . ASP D 4  59  ? -25.69065 -12.26978 57.33437  1.000 37.92707 ? 68  ASP D CB  1 
ATOM   3466 C CG  . ASP D 4  59  ? -26.71560 -11.90434 56.27443  1.000 49.26084 ? 68  ASP D CG  1 
ATOM   3467 O OD1 . ASP D 4  59  ? -27.71543 -11.23301 56.60836  1.000 44.47877 ? 68  ASP D OD1 1 
ATOM   3468 O OD2 . ASP D 4  59  ? -26.52018 -12.29209 55.10295  1.000 54.96994 ? 68  ASP D OD2 1 
ATOM   3469 N N   . GLY D 4  60  ? -28.24387 -12.08926 59.93349  1.000 36.04458 ? 74  GLY D N   1 
ATOM   3470 C CA  . GLY D 4  60  ? -29.43070 -12.75964 60.42547  1.000 27.51278 ? 74  GLY D CA  1 
ATOM   3471 C C   . GLY D 4  60  ? -29.11988 -13.83094 61.44917  1.000 27.27365 ? 74  GLY D C   1 
ATOM   3472 O O   . GLY D 4  60  ? -28.52995 -13.54730 62.49613  1.000 29.34506 ? 74  GLY D O   1 
ATOM   3473 N N   . ARG D 4  61  ? -29.51001 -15.06972 61.15570  1.000 24.70723 ? 75  ARG D N   1 
ATOM   3474 C CA  . ARG D 4  61  ? -29.25463 -16.19082 62.05051  1.000 28.13758 ? 75  ARG D CA  1 
ATOM   3475 C C   . ARG D 4  61  ? -27.86214 -16.78399 61.88128  1.000 28.62083 ? 75  ARG D C   1 
ATOM   3476 O O   . ARG D 4  61  ? -27.53356 -17.75289 62.57494  1.000 24.19912 ? 75  ARG D O   1 
ATOM   3477 C CB  . ARG D 4  61  ? -30.30087 -17.28787 61.83083  1.000 23.13858 ? 75  ARG D CB  1 
ATOM   3478 C CG  . ARG D 4  61  ? -31.73774 -16.85347 62.09164  1.000 28.25017 ? 75  ARG D CG  1 
ATOM   3479 C CD  . ARG D 4  61  ? -32.71618 -17.99718 61.84384  1.000 23.30661 ? 75  ARG D CD  1 
ATOM   3480 N NE  . ARG D 4  61  ? -32.67794 -18.46938 60.46416  1.000 24.38041 ? 75  ARG D NE  1 
ATOM   3481 C CZ  . ARG D 4  61  ? -32.21429 -19.65406 60.08814  1.000 29.29875 ? 75  ARG D CZ  1 
ATOM   3482 N NH1 . ARG D 4  61  ? -31.72741 -20.51661 60.96558  1.000 22.59704 ? 75  ARG D NH1 1 
ATOM   3483 N NH2 . ARG D 4  61  ? -32.23973 -19.98196 58.79904  1.000 23.34208 ? 75  ARG D NH2 1 
ATOM   3484 N N   . PHE D 4  62  ? -27.03964 -16.23196 60.99402  1.000 19.21791 ? 76  PHE D N   1 
ATOM   3485 C CA  . PHE D 4  62  ? -25.76482 -16.82934 60.62760  1.000 26.18704 ? 76  PHE D CA  1 
ATOM   3486 C C   . PHE D 4  62  ? -24.60679 -15.95228 61.08474  1.000 25.93813 ? 76  PHE D C   1 
ATOM   3487 O O   . PHE D 4  62  ? -24.67624 -14.72121 61.01044  1.000 29.43865 ? 76  PHE D O   1 
ATOM   3488 C CB  . PHE D 4  62  ? -25.68316 -17.05495 59.11287  1.000 24.91852 ? 76  PHE D CB  1 
ATOM   3489 C CG  . PHE D 4  62  ? -26.76067 -17.95823 58.57357  1.000 27.51182 ? 76  PHE D CG  1 
ATOM   3490 C CD1 . PHE D 4  62  ? -28.02524 -17.46374 58.29132  1.000 35.90260 ? 76  PHE D CD1 1 
ATOM   3491 C CD2 . PHE D 4  62  ? -26.50898 -19.30169 58.34988  1.000 26.64327 ? 76  PHE D CD2 1 
ATOM   3492 C CE1 . PHE D 4  62  ? -29.01725 -18.29245 57.79694  1.000 29.53061 ? 76  PHE D CE1 1 
ATOM   3493 C CE2 . PHE D 4  62  ? -27.49725 -20.13556 57.85434  1.000 26.76668 ? 76  PHE D CE2 1 
ATOM   3494 C CZ  . PHE D 4  62  ? -28.75190 -19.62997 57.57812  1.000 28.49189 ? 76  PHE D CZ  1 
ATOM   3495 N N   . THR D 4  63  ? -23.54268 -16.59836 61.55739  1.000 22.31150 ? 77  THR D N   1 
ATOM   3496 C CA  . THR D 4  63  ? -22.31263 -15.91998 61.94278  1.000 25.64299 ? 77  THR D CA  1 
ATOM   3497 C C   . THR D 4  63  ? -21.13320 -16.75749 61.47486  1.000 23.90347 ? 77  THR D C   1 
ATOM   3498 O O   . THR D 4  63  ? -21.07536 -17.95847 61.75411  1.000 23.56965 ? 77  THR D O   1 
ATOM   3499 C CB  . THR D 4  63  ? -22.23646 -15.70396 63.46070  1.000 26.12447 ? 77  THR D CB  1 
ATOM   3500 O OG1 . THR D 4  63  ? -23.18685 -14.70695 63.85466  1.000 32.16954 ? 77  THR D OG1 1 
ATOM   3501 C CG2 . THR D 4  63  ? -20.84146 -15.24700 63.86526  1.000 30.88433 ? 77  THR D CG2 1 
ATOM   3502 N N   . ALA D 4  64  ? -20.20383 -16.12798 60.76044  1.000 24.57690 ? 78  ALA D N   1 
ATOM   3503 C CA  . ALA D 4  64  ? -18.99882 -16.78440 60.27121  1.000 24.06406 ? 78  ALA D CA  1 
ATOM   3504 C C   . ALA D 4  64  ? -17.78230 -16.03796 60.79713  1.000 29.01734 ? 78  ALA D C   1 
ATOM   3505 O O   . ALA D 4  64  ? -17.70480 -14.81049 60.67907  1.000 32.89146 ? 78  ALA D O   1 
ATOM   3506 C CB  . ALA D 4  64  ? -18.97716 -16.83346 58.74118  1.000 21.85079 ? 78  ALA D CB  1 
ATOM   3507 N N   . GLN D 4  65  ? -16.83511 -16.77548 61.37225  1.000 19.47441 ? 79  GLN D N   1 
ATOM   3508 C CA  . GLN D 4  65  ? -15.68340 -16.17473 62.02572  1.000 26.45791 ? 79  GLN D CA  1 
ATOM   3509 C C   . GLN D 4  65  ? -14.40395 -16.87666 61.59726  1.000 24.44011 ? 79  GLN D C   1 
ATOM   3510 O O   . GLN D 4  65  ? -14.39698 -18.07606 61.30771  1.000 25.32308 ? 79  GLN D O   1 
ATOM   3511 C CB  . GLN D 4  65  ? -15.81581 -16.22963 63.55304  1.000 31.39910 ? 79  GLN D CB  1 
ATOM   3512 C CG  . GLN D 4  65  ? -15.12293 -15.08627 64.27243  1.000 41.67034 ? 79  GLN D CG  1 
ATOM   3513 C CD  . GLN D 4  65  ? -15.76506 -14.76738 65.60668  1.000 57.18505 ? 79  GLN D CD  1 
ATOM   3514 O OE1 . GLN D 4  65  ? -15.13436 -14.18354 66.48841  1.000 62.06227 ? 79  GLN D OE1 1 
ATOM   3515 N NE2 . GLN D 4  65  ? -17.02769 -15.15137 65.76270  1.000 55.68174 ? 79  GLN D NE2 1 
ATOM   3516 N N   . LEU D 4  66  ? -13.31712 -16.11118 61.57093  1.000 26.96393 ? 80  LEU D N   1 
ATOM   3517 C CA  . LEU D 4  66  ? -12.00446 -16.60314 61.18454  1.000 22.20096 ? 80  LEU D CA  1 
ATOM   3518 C C   . LEU D 4  66  ? -11.00659 -16.32804 62.30173  1.000 26.04910 ? 80  LEU D C   1 
ATOM   3519 O O   . LEU D 4  66  ? -11.03716 -15.26295 62.92659  1.000 22.22978 ? 80  LEU D O   1 
ATOM   3520 C CB  . LEU D 4  66  ? -11.53664 -15.94361 59.87926  1.000 21.42468 ? 80  LEU D CB  1 
ATOM   3521 C CG  . LEU D 4  66  ? -10.04227 -15.98879 59.54813  1.000 24.48924 ? 80  LEU D CG  1 
ATOM   3522 C CD1 . LEU D 4  66  ? -9.63393  -17.38109 59.09138  1.000 25.09751 ? 80  LEU D CD1 1 
ATOM   3523 C CD2 . LEU D 4  66  ? -9.69072  -14.94694 58.49245  1.000 24.85607 ? 80  LEU D CD2 1 
ATOM   3524 N N   . ASN D 4  67  ? -10.13178 -17.29887 62.55865  1.000 22.22394 ? 81  ASN D N   1 
ATOM   3525 C CA  . ASN D 4  67  ? -9.02982  -17.14872 63.50902  1.000 22.71920 ? 81  ASN D CA  1 
ATOM   3526 C C   . ASN D 4  67  ? -7.75979  -17.58674 62.78738  1.000 21.43039 ? 81  ASN D C   1 
ATOM   3527 O O   . ASN D 4  67  ? -7.52910  -18.78490 62.60060  1.000 18.76180 ? 81  ASN D O   1 
ATOM   3528 C CB  . ASN D 4  67  ? -9.26639  -17.96490 64.77932  1.000 22.39532 ? 81  ASN D CB  1 
ATOM   3529 C CG  . ASN D 4  67  ? -8.22488  -17.69183 65.85926  1.000 25.76532 ? 81  ASN D CG  1 
ATOM   3530 O OD1 . ASN D 4  67  ? -7.04236  -17.50004 65.57102  1.000 24.40858 ? 81  ASN D OD1 1 
ATOM   3531 N ND2 . ASN D 4  67  ? -8.66396  -17.68057 67.11153  1.000 22.43130 ? 81  ASN D ND2 1 
ATOM   3532 N N   . ARG D 4  68  ? -6.93723  -16.61379 62.38591  1.000 20.45725 ? 82  ARG D N   1 
ATOM   3533 C CA  . ARG D 4  68  ? -5.72808  -16.93294 61.63390  1.000 25.89048 ? 82  ARG D CA  1 
ATOM   3534 C C   . ARG D 4  68  ? -4.64920  -17.54278 62.52030  1.000 25.53375 ? 82  ARG D C   1 
ATOM   3535 O O   . ARG D 4  68  ? -3.80059  -18.29435 62.02731  1.000 26.42864 ? 82  ARG D O   1 
ATOM   3536 C CB  . ARG D 4  68  ? -5.19442  -15.68056 60.93787  1.000 26.94381 ? 82  ARG D CB  1 
ATOM   3537 C CG  . ARG D 4  68  ? -5.97989  -15.27438 59.69729  1.000 27.33845 ? 82  ARG D CG  1 
ATOM   3538 C CD  . ARG D 4  68  ? -5.28793  -14.13642 58.96245  1.000 25.39574 ? 82  ARG D CD  1 
ATOM   3539 N NE  . ARG D 4  68  ? -5.98203  -13.76231 57.73586  1.000 32.01337 ? 82  ARG D NE  1 
ATOM   3540 C CZ  . ARG D 4  68  ? -5.90823  -14.43553 56.59529  1.000 27.24406 ? 82  ARG D CZ  1 
ATOM   3541 N NH1 . ARG D 4  68  ? -5.18924  -15.54135 56.48965  1.000 27.37942 ? 82  ARG D NH1 1 
ATOM   3542 N NH2 . ARG D 4  68  ? -6.57188  -13.98742 55.53350  1.000 26.02240 ? 82  ARG D NH2 1 
ATOM   3543 N N   . ALA D 4  69  ? -4.65873  -17.23452 63.82012  1.000 25.38202 ? 83  ALA D N   1 
ATOM   3544 C CA  . ALA D 4  69  ? -3.64386  -17.78637 64.71327  1.000 26.57618 ? 83  ALA D CA  1 
ATOM   3545 C C   . ALA D 4  69  ? -3.76139  -19.30219 64.81151  1.000 25.32093 ? 83  ALA D C   1 
ATOM   3546 O O   . ALA D 4  69  ? -2.75230  -20.01477 64.78323  1.000 29.58303 ? 83  ALA D O   1 
ATOM   3547 C CB  . ALA D 4  69  ? -3.75430  -17.14636 66.09727  1.000 24.60913 ? 83  ALA D CB  1 
ATOM   3548 N N   . SER D 4  70  ? -4.98454  -19.81394 64.92439  1.000 22.84781 ? 84  SER D N   1 
ATOM   3549 C CA  . SER D 4  70  ? -5.22270  -21.24908 64.95440  1.000 19.53646 ? 84  SER D CA  1 
ATOM   3550 C C   . SER D 4  70  ? -5.60248  -21.81185 63.59300  1.000 18.93246 ? 84  SER D C   1 
ATOM   3551 O O   . SER D 4  70  ? -5.68048  -23.03797 63.44597  1.000 14.00734 ? 84  SER D O   1 
ATOM   3552 C CB  . SER D 4  70  ? -6.32694  -21.57671 65.96517  1.000 20.97835 ? 84  SER D CB  1 
ATOM   3553 O OG  . SER D 4  70  ? -7.47546  -20.78142 65.72067  1.000 23.61241 ? 84  SER D OG  1 
ATOM   3554 N N   . GLN D 4  71  ? -5.83269  -20.94659 62.60357  1.000 19.87638 ? 85  GLN D N   1 
ATOM   3555 C CA  . GLN D 4  71  ? -6.28103  -21.35230 61.27270  1.000 22.69718 ? 85  GLN D CA  1 
ATOM   3556 C C   . GLN D 4  71  ? -7.58107  -22.15199 61.36319  1.000 20.14259 ? 85  GLN D C   1 
ATOM   3557 O O   . GLN D 4  71  ? -7.70599  -23.25809 60.83280  1.000 22.40044 ? 85  GLN D O   1 
ATOM   3558 C CB  . GLN D 4  71  ? -5.17990  -22.11746 60.53070  1.000 17.67850 ? 85  GLN D CB  1 
ATOM   3559 C CG  . GLN D 4  71  ? -4.02469  -21.19887 60.13162  1.000 24.23887 ? 85  GLN D CG  1 
ATOM   3560 C CD  . GLN D 4  71  ? -2.85662  -21.91782 59.48003  1.000 23.39103 ? 85  GLN D CD  1 
ATOM   3561 O OE1 . GLN D 4  71  ? -1.71038  -21.48760 59.60202  1.000 30.66089 ? 85  GLN D OE1 1 
ATOM   3562 N NE2 . GLN D 4  71  ? -3.14122  -23.00681 58.77502  1.000 26.32427 ? 85  GLN D NE2 1 
ATOM   3563 N N   . TYR D 4  72  ? -8.55795  -21.56612 62.05215  1.000 18.38757 ? 86  TYR D N   1 
ATOM   3564 C CA  . TYR D 4  72  ? -9.88231  -22.14140 62.23172  1.000 19.54915 ? 86  TYR D CA  1 
ATOM   3565 C C   . TYR D 4  72  ? -10.92094 -21.28531 61.52039  1.000 21.40900 ? 86  TYR D C   1 
ATOM   3566 O O   . TYR D 4  72  ? -10.83131 -20.05329 61.52221  1.000 22.61207 ? 86  TYR D O   1 
ATOM   3567 C CB  . TYR D 4  72  ? -10.24272 -22.24334 63.71839  1.000 19.69802 ? 86  TYR D CB  1 
ATOM   3568 C CG  . TYR D 4  72  ? -10.22633 -23.64920 64.27142  1.000 20.03456 ? 86  TYR D CG  1 
ATOM   3569 C CD1 . TYR D 4  72  ? -11.33228 -24.47963 64.14350  1.000 20.16937 ? 86  TYR D CD1 1 
ATOM   3570 C CD2 . TYR D 4  72  ? -9.10612  -24.14480 64.92689  1.000 21.26647 ? 86  TYR D CD2 1 
ATOM   3571 C CE1 . TYR D 4  72  ? -11.32228 -25.76758 64.65029  1.000 17.33927 ? 86  TYR D CE1 1 
ATOM   3572 C CE2 . TYR D 4  72  ? -9.08647  -25.42964 65.43768  1.000 21.85855 ? 86  TYR D CE2 1 
ATOM   3573 C CZ  . TYR D 4  72  ? -10.19660 -26.23579 65.29659  1.000 18.34707 ? 86  TYR D CZ  1 
ATOM   3574 O OH  . TYR D 4  72  ? -10.17884 -27.51520 65.80067  1.000 28.80828 ? 86  TYR D OH  1 
ATOM   3575 N N   . ILE D 4  73  ? -11.90837 -21.94443 60.92041  1.000 20.08073 ? 87  ILE D N   1 
ATOM   3576 C CA  . ILE D 4  73  ? -13.06703 -21.28711 60.32773  1.000 23.10957 ? 87  ILE D CA  1 
ATOM   3577 C C   . ILE D 4  73  ? -14.31146 -21.87789 60.97285  1.000 16.29299 ? 87  ILE D C   1 
ATOM   3578 O O   . ILE D 4  73  ? -14.41656 -23.10125 61.11912  1.000 20.18611 ? 87  ILE D O   1 
ATOM   3579 C CB  . ILE D 4  73  ? -13.10882 -21.46474 58.79867  1.000 23.97503 ? 87  ILE D CB  1 
ATOM   3580 C CG1 . ILE D 4  73  ? -11.84051 -20.90588 58.15375  1.000 21.43309 ? 87  ILE D CG1 1 
ATOM   3581 C CG2 . ILE D 4  73  ? -14.34468 -20.79763 58.21190  1.000 22.21472 ? 87  ILE D CG2 1 
ATOM   3582 C CD1 . ILE D 4  73  ? -11.43300 -21.64945 56.90432  1.000 24.75001 ? 87  ILE D CD1 1 
ATOM   3583 N N   . SER D 4  74  ? -15.24836 -21.01682 61.36000  1.000 15.51150 ? 88  SER D N   1 
ATOM   3584 C CA  . SER D 4  74  ? -16.46244 -21.45917 62.02685  1.000 21.34930 ? 88  SER D CA  1 
ATOM   3585 C C   . SER D 4  74  ? -17.68816 -20.84362 61.36873  1.000 19.88598 ? 88  SER D C   1 
ATOM   3586 O O   . SER D 4  74  ? -17.63614 -19.73974 60.81934  1.000 22.56797 ? 88  SER D O   1 
ATOM   3587 C CB  . SER D 4  74  ? -16.44754 -21.10204 63.52059  1.000 20.47867 ? 88  SER D CB  1 
ATOM   3588 O OG  . SER D 4  74  ? -16.39894 -19.69869 63.70883  1.000 27.82167 ? 88  SER D OG  1 
ATOM   3589 N N   . LEU D 4  75  ? -18.79606 -21.57777 61.43211  1.000 21.44023 ? 89  LEU D N   1 
ATOM   3590 C CA  . LEU D 4  75  ? -20.10118 -21.07713 61.02617  1.000 21.95281 ? 89  LEU D CA  1 
ATOM   3591 C C   . LEU D 4  75  ? -21.09734 -21.38144 62.13160  1.000 18.26408 ? 89  LEU D C   1 
ATOM   3592 O O   . LEU D 4  75  ? -21.17860 -22.52148 62.60005  1.000 18.15300 ? 89  LEU D O   1 
ATOM   3593 C CB  . LEU D 4  75  ? -20.57217 -21.70325 59.70960  1.000 19.44978 ? 89  LEU D CB  1 
ATOM   3594 C CG  . LEU D 4  75  ? -22.02756 -21.38171 59.35318  1.000 21.41204 ? 89  LEU D CG  1 
ATOM   3595 C CD1 . LEU D 4  75  ? -22.16943 -19.91766 58.95999  1.000 21.01697 ? 89  LEU D CD1 1 
ATOM   3596 C CD2 . LEU D 4  75  ? -22.54660 -22.29540 58.25244  1.000 17.60561 ? 89  LEU D CD2 1 
ATOM   3597 N N   . LEU D 4  76  ? -21.84501 -20.36480 62.54742  1.000 15.29715 ? 90  LEU D N   1 
ATOM   3598 C CA  . LEU D 4  76  ? -22.87021 -20.50201 63.57192  1.000 23.72316 ? 90  LEU D CA  1 
ATOM   3599 C C   . LEU D 4  76  ? -24.23655 -20.24942 62.95342  1.000 19.18556 ? 90  LEU D C   1 
ATOM   3600 O O   . LEU D 4  76  ? -24.42712 -19.25520 62.24556  1.000 23.13746 ? 90  LEU D O   1 
ATOM   3601 C CB  . LEU D 4  76  ? -22.62673 -19.52723 64.72600  1.000 24.52717 ? 90  LEU D CB  1 
ATOM   3602 C CG  . LEU D 4  76  ? -21.38106 -19.80334 65.56674  1.000 29.78892 ? 90  LEU D CG  1 
ATOM   3603 C CD1 . LEU D 4  76  ? -21.06630 -18.62780 66.47997  1.000 29.30944 ? 90  LEU D CD1 1 
ATOM   3604 C CD2 . LEU D 4  76  ? -21.57272 -21.07522 66.36693  1.000 29.85655 ? 90  LEU D CD2 1 
ATOM   3605 N N   . ILE D 4  77  ? -25.17744 -21.15146 63.21133  1.000 17.51310 ? 91  ILE D N   1 
ATOM   3606 C CA  . ILE D 4  77  ? -26.56297 -20.99165 62.78793  1.000 19.67240 ? 91  ILE D CA  1 
ATOM   3607 C C   . ILE D 4  77  ? -27.41933 -21.00541 64.04471  1.000 21.66576 ? 91  ILE D C   1 
ATOM   3608 O O   . ILE D 4  77  ? -27.53486 -22.04009 64.71435  1.000 18.79458 ? 91  ILE D O   1 
ATOM   3609 C CB  . ILE D 4  77  ? -27.00566 -22.08522 61.80662  1.000 19.31414 ? 91  ILE D CB  1 
ATOM   3610 C CG1 . ILE D 4  77  ? -26.07653 -22.13122 60.59216  1.000 20.16499 ? 91  ILE D CG1 1 
ATOM   3611 C CG2 . ILE D 4  77  ? -28.44672 -21.85455 61.36619  1.000 16.10014 ? 91  ILE D CG2 1 
ATOM   3612 C CD1 . ILE D 4  77  ? -26.34680 -23.30022 59.67155  1.000 19.59462 ? 91  ILE D CD1 1 
ATOM   3613 N N   . ARG D 4  78  ? -28.00463 -19.85957 64.37456  1.000 25.25226 ? 92  ARG D N   1 
ATOM   3614 C CA  . ARG D 4  78  ? -28.92521 -19.75533 65.49460  1.000 24.46381 ? 92  ARG D CA  1 
ATOM   3615 C C   . ARG D 4  78  ? -30.34101 -20.07856 65.03769  1.000 24.31675 ? 92  ARG D C   1 
ATOM   3616 O O   . ARG D 4  78  ? -30.70026 -19.86133 63.87629  1.000 21.34951 ? 92  ARG D O   1 
ATOM   3617 C CB  . ARG D 4  78  ? -28.88706 -18.35225 66.10299  1.000 26.97617 ? 92  ARG D CB  1 
ATOM   3618 C CG  . ARG D 4  78  ? -27.49426 -17.76701 66.23072  1.000 39.24945 ? 92  ARG D CG  1 
ATOM   3619 C CD  . ARG D 4  78  ? -27.54152 -16.28762 66.59513  1.000 46.32525 ? 92  ARG D CD  1 
ATOM   3620 N NE  . ARG D 4  78  ? -27.41934 -15.41887 65.42875  1.000 45.42371 ? 92  ARG D NE  1 
ATOM   3621 C CZ  . ARG D 4  78  ? -26.31683 -15.27574 64.70460  1.000 39.03225 ? 92  ARG D CZ  1 
ATOM   3622 N NH1 . ARG D 4  78  ? -25.20680 -15.93523 64.99413  1.000 35.49818 ? 92  ARG D NH1 1 
ATOM   3623 N NH2 . ARG D 4  78  ? -26.32751 -14.44722 63.66406  1.000 42.94352 ? 92  ARG D NH2 1 
ATOM   3624 N N   . ASP D 4  79  ? -31.13917 -20.60567 65.96771  1.000 22.96947 ? 93  ASP D N   1 
ATOM   3625 C CA  . ASP D 4  79  ? -32.55816 -20.89256 65.75002  1.000 18.18342 ? 93  ASP D CA  1 
ATOM   3626 C C   . ASP D 4  79  ? -32.77144 -21.68242 64.45764  1.000 21.97208 ? 93  ASP D C   1 
ATOM   3627 O O   . ASP D 4  79  ? -33.45592 -21.24413 63.53088  1.000 19.58306 ? 93  ASP D O   1 
ATOM   3628 C CB  . ASP D 4  79  ? -33.37355 -19.59721 65.74190  1.000 23.01313 ? 93  ASP D CB  1 
ATOM   3629 C CG  . ASP D 4  79  ? -33.00204 -18.66619 66.88132  1.000 39.93801 ? 93  ASP D CG  1 
ATOM   3630 O OD1 . ASP D 4  79  ? -33.04237 -19.10418 68.05205  1.000 34.73267 ? 93  ASP D OD1 1 
ATOM   3631 O OD2 . ASP D 4  79  ? -32.66569 -17.49489 66.60480  1.000 39.42847 ? 93  ASP D OD2 1 
ATOM   3632 N N   . SER D 4  80  ? -32.16390 -22.86677 64.41188  1.000 22.00718 ? 94  SER D N   1 
ATOM   3633 C CA  . SER D 4  80  ? -32.15640 -23.65433 63.18535  1.000 25.45878 ? 94  SER D CA  1 
ATOM   3634 C C   . SER D 4  80  ? -33.57070 -24.06411 62.79071  1.000 22.02489 ? 94  SER D C   1 
ATOM   3635 O O   . SER D 4  80  ? -34.40958 -24.36759 63.64310  1.000 21.14508 ? 94  SER D O   1 
ATOM   3636 C CB  . SER D 4  80  ? -31.28279 -24.89678 63.35807  1.000 18.19991 ? 94  SER D CB  1 
ATOM   3637 O OG  . SER D 4  80  ? -31.60798 -25.58390 64.55380  1.000 25.94593 ? 94  SER D OG  1 
ATOM   3638 N N   . LYS D 4  81  ? -33.83016 -24.06657 61.48599  1.000 29.02713 ? 95  LYS D N   1 
ATOM   3639 C CA  . LYS D 4  81  ? -35.10589 -24.48343 60.92296  1.000 30.38147 ? 95  LYS D CA  1 
ATOM   3640 C C   . LYS D 4  81  ? -34.91387 -25.73190 60.07144  1.000 28.79846 ? 95  LYS D C   1 
ATOM   3641 O O   . LYS D 4  81  ? -33.79170 -26.11710 59.73150  1.000 23.09371 ? 95  LYS D O   1 
ATOM   3642 C CB  . LYS D 4  81  ? -35.73647 -23.37341 60.07187  1.000 29.73145 ? 95  LYS D CB  1 
ATOM   3643 C CG  . LYS D 4  81  ? -35.45184 -21.95700 60.53459  1.000 32.98220 ? 95  LYS D CG  1 
ATOM   3644 C CD  . LYS D 4  81  ? -35.58406 -20.99192 59.36524  1.000 36.14596 ? 95  LYS D CD  1 
ATOM   3645 C CE  . LYS D 4  81  ? -36.22819 -19.67963 59.78206  1.000 43.60977 ? 95  LYS D CE  1 
ATOM   3646 N NZ  . LYS D 4  81  ? -35.99964 -18.61430 58.76401  1.000 46.42983 ? 95  LYS D NZ  1 
ATOM   3647 N N   . LEU D 4  82  ? -36.03919 -26.35990 59.71797  1.000 24.56623 ? 96  LEU D N   1 
ATOM   3648 C CA  . LEU D 4  82  ? -35.99065 -27.54053 58.86030  1.000 31.06966 ? 96  LEU D CA  1 
ATOM   3649 C C   . LEU D 4  82  ? -35.34995 -27.22316 57.51517  1.000 23.01262 ? 96  LEU D C   1 
ATOM   3650 O O   . LEU D 4  82  ? -34.64396 -28.06131 56.94305  1.000 24.63535 ? 96  LEU D O   1 
ATOM   3651 C CB  . LEU D 4  82  ? -37.39642 -28.10359 58.65504  1.000 26.37462 ? 96  LEU D CB  1 
ATOM   3652 C CG  . LEU D 4  82  ? -38.19099 -28.48510 59.90170  1.000 31.40789 ? 96  LEU D CG  1 
ATOM   3653 C CD1 . LEU D 4  82  ? -39.56954 -28.97736 59.50140  1.000 37.29385 ? 96  LEU D CD1 1 
ATOM   3654 C CD2 . LEU D 4  82  ? -37.45406 -29.54270 60.70390  1.000 28.23799 ? 96  LEU D CD2 1 
ATOM   3655 N N   . SER D 4  83  ? -35.58190 -26.01604 56.99436  1.000 21.48684 ? 97  SER D N   1 
ATOM   3656 C CA  . SER D 4  83  ? -35.01824 -25.63272 55.70551  1.000 29.99853 ? 97  SER D CA  1 
ATOM   3657 C C   . SER D 4  83  ? -33.50683 -25.44627 55.75009  1.000 27.48163 ? 97  SER D C   1 
ATOM   3658 O O   . SER D 4  83  ? -32.89319 -25.28692 54.68947  1.000 26.26445 ? 97  SER D O   1 
ATOM   3659 C CB  . SER D 4  83  ? -35.68413 -24.35051 55.20066  1.000 22.51658 ? 97  SER D CB  1 
ATOM   3660 O OG  . SER D 4  83  ? -35.71292 -23.35884 56.21221  1.000 28.33417 ? 97  SER D OG  1 
ATOM   3661 N N   . ASP D 4  84  ? -32.89632 -25.45731 56.93896  1.000 21.70763 ? 98  ASP D N   1 
ATOM   3662 C CA  . ASP D 4  84  ? -31.44385 -25.38330 57.04718  1.000 22.60699 ? 98  ASP D CA  1 
ATOM   3663 C C   . ASP D 4  84  ? -30.76448 -26.70946 56.73122  1.000 21.26519 ? 98  ASP D C   1 
ATOM   3664 O O   . ASP D 4  84  ? -29.54762 -26.72750 56.51046  1.000 22.43415 ? 98  ASP D O   1 
ATOM   3665 C CB  . ASP D 4  84  ? -31.03373 -24.93030 58.45336  1.000 22.13707 ? 98  ASP D CB  1 
ATOM   3666 C CG  . ASP D 4  84  ? -31.39021 -23.48050 58.73286  1.000 22.78990 ? 98  ASP D CG  1 
ATOM   3667 O OD1 . ASP D 4  84  ? -31.32124 -22.65379 57.79990  1.000 27.59686 ? 98  ASP D OD1 1 
ATOM   3668 O OD2 . ASP D 4  84  ? -31.73220 -23.16653 59.89240  1.000 20.31075 ? 98  ASP D OD2 1 
ATOM   3669 N N   . SER D 4  85  ? -31.51665 -27.81022 56.71544  1.000 19.69752 ? 99  SER D N   1 
ATOM   3670 C CA  . SER D 4  85  ? -30.94998 -29.12509 56.43633  1.000 22.95121 ? 99  SER D CA  1 
ATOM   3671 C C   . SER D 4  85  ? -30.26092 -29.13432 55.07811  1.000 26.79155 ? 99  SER D C   1 
ATOM   3672 O O   . SER D 4  85  ? -30.90668 -28.94040 54.04360  1.000 22.41627 ? 99  SER D O   1 
ATOM   3673 C CB  . SER D 4  85  ? -32.05043 -30.18595 56.47694  1.000 19.65186 ? 99  SER D CB  1 
ATOM   3674 O OG  . SER D 4  85  ? -32.49010 -30.42432 57.80219  1.000 23.96432 ? 99  SER D OG  1 
ATOM   3675 N N   . ALA D 4  86  ? -28.95327 -29.36904 55.08737  1.000 20.40928 ? 100 ALA D N   1 
ATOM   3676 C CA  . ALA D 4  86  ? -28.13074 -29.37630 53.88120  1.000 21.32615 ? 100 ALA D CA  1 
ATOM   3677 C C   . ALA D 4  86  ? -26.72509 -29.80802 54.27776  1.000 23.25203 ? 100 ALA D C   1 
ATOM   3678 O O   . ALA D 4  86  ? -26.45096 -30.10315 55.44449  1.000 21.13217 ? 100 ALA D O   1 
ATOM   3679 C CB  . ALA D 4  86  ? -28.11511 -28.00377 53.20026  1.000 22.29582 ? 100 ALA D CB  1 
ATOM   3680 N N   . THR D 4  87  ? -25.83431 -29.84149 53.29269  1.000 21.08657 ? 101 THR D N   1 
ATOM   3681 C CA  . THR D 4  87  ? -24.41236 -30.04672 53.52610  1.000 18.14882 ? 101 THR D CA  1 
ATOM   3682 C C   . THR D 4  87  ? -23.70683 -28.70341 53.41010  1.000 23.76350 ? 101 THR D C   1 
ATOM   3683 O O   . THR D 4  87  ? -23.90826 -27.97463 52.43297  1.000 20.07278 ? 101 THR D O   1 
ATOM   3684 C CB  . THR D 4  87  ? -23.82102 -31.04617 52.53074  1.000 22.84850 ? 101 THR D CB  1 
ATOM   3685 O OG1 . THR D 4  87  ? -24.42709 -32.33019 52.72058  1.000 23.03194 ? 101 THR D OG1 1 
ATOM   3686 C CG2 . THR D 4  87  ? -22.31417 -31.17395 52.73250  1.000 23.05279 ? 101 THR D CG2 1 
ATOM   3687 N N   . TYR D 4  88  ? -22.89019 -28.37651 54.40589  1.000 20.88010 ? 102 TYR D N   1 
ATOM   3688 C CA  . TYR D 4  88  ? -22.24508 -27.07377 54.49619  1.000 18.03031 ? 102 TYR D CA  1 
ATOM   3689 C C   . TYR D 4  88  ? -20.76835 -27.22897 54.16568  1.000 19.42041 ? 102 TYR D C   1 
ATOM   3690 O O   . TYR D 4  88  ? -20.04916 -27.97358 54.84107  1.000 18.68027 ? 102 TYR D O   1 
ATOM   3691 C CB  . TYR D 4  88  ? -22.46125 -26.46286 55.88186  1.000 17.33736 ? 102 TYR D CB  1 
ATOM   3692 C CG  . TYR D 4  88  ? -23.88945 -26.00081 56.04916  1.000 17.67190 ? 102 TYR D CG  1 
ATOM   3693 C CD1 . TYR D 4  88  ? -24.90959 -26.91420 56.28234  1.000 13.85531 ? 102 TYR D CD1 1 
ATOM   3694 C CD2 . TYR D 4  88  ? -24.22797 -24.66068 55.91330  1.000 17.60428 ? 102 TYR D CD2 1 
ATOM   3695 C CE1 . TYR D 4  88  ? -26.22095 -26.50509 56.40170  1.000 17.10203 ? 102 TYR D CE1 1 
ATOM   3696 C CE2 . TYR D 4  88  ? -25.54072 -24.23952 56.03582  1.000 17.76652 ? 102 TYR D CE2 1 
ATOM   3697 C CZ  . TYR D 4  88  ? -26.53205 -25.16819 56.27986  1.000 20.52067 ? 102 TYR D CZ  1 
ATOM   3698 O OH  . TYR D 4  88  ? -27.84156 -24.76375 56.40302  1.000 25.08154 ? 102 TYR D OH  1 
ATOM   3699 N N   . LEU D 4  89  ? -20.32873 -26.53616 53.11934  1.000 20.30899 ? 103 LEU D N   1 
ATOM   3700 C CA  . LEU D 4  89  ? -18.98193 -26.67767 52.58697  1.000 20.60981 ? 103 LEU D CA  1 
ATOM   3701 C C   . LEU D 4  89  ? -18.12514 -25.49547 53.01379  1.000 18.90956 ? 103 LEU D C   1 
ATOM   3702 O O   . LEU D 4  89  ? -18.51269 -24.33747 52.82490  1.000 16.46153 ? 103 LEU D O   1 
ATOM   3703 C CB  . LEU D 4  89  ? -19.00556 -26.77950 51.06043  1.000 20.61366 ? 103 LEU D CB  1 
ATOM   3704 C CG  . LEU D 4  89  ? -20.01659 -27.74747 50.44406  1.000 22.53666 ? 103 LEU D CG  1 
ATOM   3705 C CD1 . LEU D 4  89  ? -20.08300 -27.55787 48.93502  1.000 21.09646 ? 103 LEU D CD1 1 
ATOM   3706 C CD2 . LEU D 4  89  ? -19.66247 -29.18294 50.78800  1.000 20.06789 ? 103 LEU D CD2 1 
ATOM   3707 N N   . CYS D 4  90  ? -16.96715 -25.79716 53.59038  1.000 17.86868 ? 104 CYS D N   1 
ATOM   3708 C CA  . CYS D 4  90  ? -15.95253 -24.80171 53.89790  1.000 21.31235 ? 104 CYS D CA  1 
ATOM   3709 C C   . CYS D 4  90  ? -15.05816 -24.62582 52.67551  1.000 19.25188 ? 104 CYS D C   1 
ATOM   3710 O O   . CYS D 4  90  ? -14.52452 -25.60652 52.14812  1.000 19.37025 ? 104 CYS D O   1 
ATOM   3711 C CB  . CYS D 4  90  ? -15.14345 -25.24981 55.11646  1.000 20.81189 ? 104 CYS D CB  1 
ATOM   3712 S SG  . CYS D 4  90  ? -13.71348 -24.25641 55.54553  1.000 27.46226 ? 104 CYS D SG  1 
ATOM   3713 N N   . VAL D 4  91  ? -14.91321 -23.38380 52.21364  1.000 17.92892 ? 105 VAL D N   1 
ATOM   3714 C CA  . VAL D 4  91  ? -14.21577 -23.08319 50.96622  1.000 17.87600 ? 105 VAL D CA  1 
ATOM   3715 C C   . VAL D 4  91  ? -13.11223 -22.07265 51.24871  1.000 20.47148 ? 105 VAL D C   1 
ATOM   3716 O O   . VAL D 4  91  ? -13.36744 -21.01542 51.83691  1.000 20.69900 ? 105 VAL D O   1 
ATOM   3717 C CB  . VAL D 4  91  ? -15.18211 -22.55044 49.89105  1.000 23.63976 ? 105 VAL D CB  1 
ATOM   3718 C CG1 . VAL D 4  91  ? -14.44711 -22.30760 48.58324  1.000 18.09417 ? 105 VAL D CG1 1 
ATOM   3719 C CG2 . VAL D 4  91  ? -16.33176 -23.52880 49.68767  1.000 21.33096 ? 105 VAL D CG2 1 
ATOM   3720 N N   . VAL D 4  92  ? -11.89198 -22.39153 50.81710  1.000 16.22476 ? 106 VAL D N   1 
ATOM   3721 C CA  . VAL D 4  92  ? -10.70040 -21.62588 51.16517  1.000 19.12105 ? 106 VAL D CA  1 
ATOM   3722 C C   . VAL D 4  92  ? -9.98272  -21.21358 49.88764  1.000 21.03551 ? 106 VAL D C   1 
ATOM   3723 O O   . VAL D 4  92  ? -9.67403  -22.06031 49.04139  1.000 20.53048 ? 106 VAL D O   1 
ATOM   3724 C CB  . VAL D 4  92  ? -9.75859  -22.43452 52.07750  1.000 23.40399 ? 106 VAL D CB  1 
ATOM   3725 C CG1 . VAL D 4  92  ? -8.47583  -21.66433 52.33689  1.000 17.94425 ? 106 VAL D CG1 1 
ATOM   3726 C CG2 . VAL D 4  92  ? -10.45700 -22.77692 53.38350  1.000 17.56375 ? 106 VAL D CG2 1 
ATOM   3727 N N   . MET D 4  93  ? -9.70011  -19.91988 49.75905  1.000 22.47120 ? 107 MET D N   1 
ATOM   3728 C CA  . MET D 4  93  ? -9.06724  -19.36253 48.57026  1.000 20.91433 ? 107 MET D CA  1 
ATOM   3729 C C   . MET D 4  93  ? -7.61925  -19.00141 48.87937  1.000 25.49997 ? 107 MET D C   1 
ATOM   3730 O O   . MET D 4  93  ? -7.35534  -18.15186 49.73773  1.000 22.02841 ? 107 MET D O   1 
ATOM   3731 C CB  . MET D 4  93  ? -9.82658  -18.13270 48.07291  1.000 23.37164 ? 107 MET D CB  1 
ATOM   3732 C CG  . MET D 4  93  ? -9.20090  -17.47971 46.84736  1.000 31.16272 ? 107 MET D CG  1 
ATOM   3733 S SD  . MET D 4  93  ? -9.98523  -15.91975 46.40227  1.000 31.66397 ? 107 MET D SD  1 
ATOM   3734 C CE  . MET D 4  93  ? -8.95836  -14.76705 47.31479  1.000 20.47941 ? 107 MET D CE  1 
ATOM   3735 N N   . GLY D 4  94  ? -6.68985  -19.64759 48.17989  1.000 25.62133 ? 108 GLY D N   1 
ATOM   3736 C CA  . GLY D 4  94  ? -5.29019  -19.27155 48.22003  1.000 29.71215 ? 108 GLY D CA  1 
ATOM   3737 C C   . GLY D 4  94  ? -4.83413  -18.79032 46.85785  1.000 31.87781 ? 108 GLY D C   1 
ATOM   3738 O O   . GLY D 4  94  ? -5.66389  -18.61583 45.95979  1.000 29.69123 ? 108 GLY D O   1 
ATOM   3739 N N   . PHE D 4  95  ? -3.53108  -18.57132 46.67808  1.000 26.57237 ? 109 PHE D N   1 
ATOM   3740 C CA  . PHE D 4  95  ? -3.04017  -18.12197 45.38052  1.000 26.41988 ? 109 PHE D CA  1 
ATOM   3741 C C   . PHE D 4  95  ? -3.26557  -19.19337 44.32287  1.000 28.36986 ? 109 PHE D C   1 
ATOM   3742 O O   . PHE D 4  95  ? -2.68196  -20.28006 44.39445  1.000 26.26709 ? 109 PHE D O   1 
ATOM   3743 C CB  . PHE D 4  95  ? -1.55674  -17.75226 45.43746  1.000 27.15990 ? 109 PHE D CB  1 
ATOM   3744 C CG  . PHE D 4  95  ? -1.00295  -17.29761 44.11377  1.000 29.83582 ? 109 PHE D CG  1 
ATOM   3745 C CD1 . PHE D 4  95  ? -1.49003  -16.15323 43.50182  1.000 29.82738 ? 109 PHE D CD1 1 
ATOM   3746 C CD2 . PHE D 4  95  ? -0.01265  -18.02348 43.47172  1.000 31.58813 ? 109 PHE D CD2 1 
ATOM   3747 C CE1 . PHE D 4  95  ? -0.99077  -15.73406 42.28026  1.000 32.00123 ? 109 PHE D CE1 1 
ATOM   3748 C CE2 . PHE D 4  95  ? 0.49018   -17.60982 42.24903  1.000 35.52501 ? 109 PHE D CE2 1 
ATOM   3749 C CZ  . PHE D 4  95  ? -0.00012  -16.46407 41.65281  1.000 27.05216 ? 109 PHE D CZ  1 
ATOM   3750 N N   . GLN D 4  96  ? -4.11998  -18.89166 43.34474  1.000 28.80526 ? 110 GLN D N   1 
ATOM   3751 C CA  . GLN D 4  96  ? -4.42349  -19.80182 42.24193  1.000 33.75352 ? 110 GLN D CA  1 
ATOM   3752 C C   . GLN D 4  96  ? -4.92452  -21.15547 42.74149  1.000 34.15738 ? 110 GLN D C   1 
ATOM   3753 O O   . GLN D 4  96  ? -4.65743  -22.19333 42.13110  1.000 31.21583 ? 110 GLN D O   1 
ATOM   3754 C CB  . GLN D 4  96  ? -3.21039  -19.97754 41.32180  1.000 33.14020 ? 110 GLN D CB  1 
ATOM   3755 C CG  . GLN D 4  96  ? -3.00625  -18.81520 40.35836  1.000 38.25464 ? 110 GLN D CG  1 
ATOM   3756 C CD  . GLN D 4  96  ? -1.77090  -18.97436 39.49364  1.000 45.31365 ? 110 GLN D CD  1 
ATOM   3757 O OE1 . GLN D 4  96  ? -0.92361  -19.83033 39.75035  1.000 41.41919 ? 110 GLN D OE1 1 
ATOM   3758 N NE2 . GLN D 4  96  ? -1.66357  -18.14749 38.45898  1.000 43.41278 ? 110 GLN D NE2 1 
ATOM   3759 N N   . LYS D 4  97  ? -5.67403  -21.15678 43.84283  1.000 34.01540 ? 111 LYS D N   1 
ATOM   3760 C CA  . LYS D 4  97  ? -6.25355  -22.38742 44.36430  1.000 30.33665 ? 111 LYS D CA  1 
ATOM   3761 C C   . LYS D 4  97  ? -7.50984  -22.06142 45.15694  1.000 29.62227 ? 111 LYS D C   1 
ATOM   3762 O O   . LYS D 4  97  ? -7.47413  -21.22968 46.06819  1.000 29.85611 ? 111 LYS D O   1 
ATOM   3763 C CB  . LYS D 4  97  ? -5.25158  -23.14345 45.24417  1.000 38.11091 ? 111 LYS D CB  1 
ATOM   3764 C CG  . LYS D 4  97  ? -4.80762  -24.47879 44.66575  1.000 48.14448 ? 111 LYS D CG  1 
ATOM   3765 C CD  . LYS D 4  97  ? -5.60322  -25.62944 45.26130  1.000 48.36197 ? 111 LYS D CD  1 
ATOM   3766 C CE  . LYS D 4  97  ? -5.00774  -26.97618 44.88003  1.000 58.69411 ? 111 LYS D CE  1 
ATOM   3767 N NZ  . LYS D 4  97  ? -5.82055  -28.11257 45.39978  1.000 64.96048 ? 111 LYS D NZ  1 
ATOM   3768 N N   . LEU D 4  98  ? -8.61318  -22.71674 44.80327  1.000 26.78198 ? 112 LEU D N   1 
ATOM   3769 C CA  . LEU D 4  98  ? -9.87509  -22.61760 45.53041  1.000 25.16658 ? 112 LEU D CA  1 
ATOM   3770 C C   . LEU D 4  98  ? -10.28686 -24.03243 45.91302  1.000 24.80443 ? 112 LEU D C   1 
ATOM   3771 O O   . LEU D 4  98  ? -10.62397 -24.84085 45.04153  1.000 23.28397 ? 112 LEU D O   1 
ATOM   3772 C CB  . LEU D 4  98  ? -10.94911 -21.93351 44.68519  1.000 26.71256 ? 112 LEU D CB  1 
ATOM   3773 C CG  . LEU D 4  98  ? -12.28552 -21.64675 45.37495  1.000 25.22715 ? 112 LEU D CG  1 
ATOM   3774 C CD1 . LEU D 4  98  ? -12.13666 -20.53497 46.40416  1.000 18.06450 ? 112 LEU D CD1 1 
ATOM   3775 C CD2 . LEU D 4  98  ? -13.34562 -21.28786 44.34625  1.000 23.21946 ? 112 LEU D CD2 1 
ATOM   3776 N N   . VAL D 4  99  ? -10.24939 -24.33812 47.20760  1.000 18.28131 ? 113 VAL D N   1 
ATOM   3777 C CA  . VAL D 4  99  ? -10.43985 -25.69776 47.69888  1.000 19.15448 ? 113 VAL D CA  1 
ATOM   3778 C C   . VAL D 4  99  ? -11.80479 -25.80279 48.36187  1.000 22.04196 ? 113 VAL D C   1 
ATOM   3779 O O   . VAL D 4  99  ? -12.12634 -25.02621 49.27011  1.000 20.58014 ? 113 VAL D O   1 
ATOM   3780 C CB  . VAL D 4  99  ? -9.32456  -26.10802 48.67486  1.000 23.87110 ? 113 VAL D CB  1 
ATOM   3781 C CG1 . VAL D 4  99  ? -9.56390  -27.52276 49.17628  1.000 22.94909 ? 113 VAL D CG1 1 
ATOM   3782 C CG2 . VAL D 4  99  ? -7.96319  -25.99856 48.00095  1.000 24.18810 ? 113 VAL D CG2 1 
ATOM   3783 N N   . PHE D 4  100 ? -12.59967 -26.76834 47.91071  1.000 19.85612 ? 114 PHE D N   1 
ATOM   3784 C CA  . PHE D 4  100 ? -13.88677 -27.08537 48.51267  1.000 20.23263 ? 114 PHE D CA  1 
ATOM   3785 C C   . PHE D 4  100 ? -13.69667 -28.24074 49.48688  1.000 23.24055 ? 114 PHE D C   1 
ATOM   3786 O O   . PHE D 4  100 ? -13.20680 -29.30788 49.10018  1.000 20.96895 ? 114 PHE D O   1 
ATOM   3787 C CB  . PHE D 4  100 ? -14.91654 -27.45739 47.44421  1.000 16.00992 ? 114 PHE D CB  1 
ATOM   3788 C CG  . PHE D 4  100 ? -15.47797 -26.27913 46.69982  1.000 20.63551 ? 114 PHE D CG  1 
ATOM   3789 C CD1 . PHE D 4  100 ? -14.74281 -25.65497 45.70597  1.000 23.88725 ? 114 PHE D CD1 1 
ATOM   3790 C CD2 . PHE D 4  100 ? -16.74649 -25.80177 46.98808  1.000 25.12833 ? 114 PHE D CD2 1 
ATOM   3791 C CE1 . PHE D 4  100 ? -15.25857 -24.57268 45.01847  1.000 22.90114 ? 114 PHE D CE1 1 
ATOM   3792 C CE2 . PHE D 4  100 ? -17.26792 -24.71884 46.30449  1.000 20.28523 ? 114 PHE D CE2 1 
ATOM   3793 C CZ  . PHE D 4  100 ? -16.52325 -24.10431 45.31827  1.000 20.47859 ? 114 PHE D CZ  1 
ATOM   3794 N N   . GLY D 4  101 ? -14.07133 -28.02668 50.74519  1.000 20.10233 ? 115 GLY D N   1 
ATOM   3795 C CA  . GLY D 4  101 ? -14.10615 -29.12123 51.68917  1.000 16.21122 ? 115 GLY D CA  1 
ATOM   3796 C C   . GLY D 4  101 ? -15.17732 -30.13247 51.33266  1.000 23.09560 ? 115 GLY D C   1 
ATOM   3797 O O   . GLY D 4  101 ? -16.07688 -29.87600 50.53053  1.000 22.08713 ? 115 GLY D O   1 
ATOM   3798 N N   . THR D 4  102 ? -15.07434 -31.31662 51.93531  1.000 19.92130 ? 116 THR D N   1 
ATOM   3799 C CA  . THR D 4  102 ? -16.06006 -32.35742 51.67161  1.000 22.66784 ? 116 THR D CA  1 
ATOM   3800 C C   . THR D 4  102 ? -17.37051 -32.13088 52.41468  1.000 24.97957 ? 116 THR D C   1 
ATOM   3801 O O   . THR D 4  102 ? -18.34114 -32.85140 52.15802  1.000 22.64928 ? 116 THR D O   1 
ATOM   3802 C CB  . THR D 4  102 ? -15.48925 -33.73569 52.01881  1.000 23.08592 ? 116 THR D CB  1 
ATOM   3803 O OG1 . THR D 4  102 ? -14.78950 -33.66883 53.26673  1.000 28.39150 ? 116 THR D OG1 1 
ATOM   3804 C CG2 . THR D 4  102 ? -14.52967 -34.19847 50.92543  1.000 27.68329 ? 116 THR D CG2 1 
ATOM   3805 N N   . GLY D 4  103 ? -17.42220 -31.16064 53.32013  1.000 23.87076 ? 117 GLY D N   1 
ATOM   3806 C CA  . GLY D 4  103 ? -18.67425 -30.70835 53.88677  1.000 25.53189 ? 117 GLY D CA  1 
ATOM   3807 C C   . GLY D 4  103 ? -19.05469 -31.42428 55.17180  1.000 25.06348 ? 117 GLY D C   1 
ATOM   3808 O O   . GLY D 4  103 ? -18.50922 -32.46620 55.53264  1.000 25.11349 ? 117 GLY D O   1 
ATOM   3809 N N   . THR D 4  104 ? -20.01749 -30.82794 55.87258  1.000 23.75658 ? 118 THR D N   1 
ATOM   3810 C CA  . THR D 4  104 ? -20.63290 -31.41616 57.05612  1.000 20.08710 ? 118 THR D CA  1 
ATOM   3811 C C   . THR D 4  104 ? -22.13920 -31.42799 56.84287  1.000 22.80514 ? 118 THR D C   1 
ATOM   3812 O O   . THR D 4  104 ? -22.75075 -30.36871 56.66988  1.000 19.25165 ? 118 THR D O   1 
ATOM   3813 C CB  . THR D 4  104 ? -20.27572 -30.63141 58.32255  1.000 20.69599 ? 118 THR D CB  1 
ATOM   3814 O OG1 . THR D 4  104 ? -18.85114 -30.52131 58.43836  1.000 25.15921 ? 118 THR D OG1 1 
ATOM   3815 C CG2 . THR D 4  104 ? -20.83080 -31.32900 59.55832  1.000 20.96825 ? 118 THR D CG2 1 
ATOM   3816 N N   . ARG D 4  105 ? -22.73327 -32.61742 56.84716  1.000 20.07926 ? 119 ARG D N   1 
ATOM   3817 C CA  . ARG D 4  105 ? -24.16310 -32.74820 56.60249  1.000 23.81256 ? 119 ARG D CA  1 
ATOM   3818 C C   . ARG D 4  105 ? -24.95160 -32.38052 57.85544  1.000 23.78275 ? 119 ARG D C   1 
ATOM   3819 O O   . ARG D 4  105 ? -24.66690 -32.87936 58.94892  1.000 23.47197 ? 119 ARG D O   1 
ATOM   3820 C CB  . ARG D 4  105 ? -24.49769 -34.17230 56.15961  1.000 21.79353 ? 119 ARG D CB  1 
ATOM   3821 C CG  . ARG D 4  105 ? -25.98336 -34.43161 55.97001  1.000 33.00305 ? 119 ARG D CG  1 
ATOM   3822 C CD  . ARG D 4  105 ? -26.22967 -35.58585 55.01122  1.000 36.60572 ? 119 ARG D CD  1 
ATOM   3823 N NE  . ARG D 4  105 ? -27.59360 -35.58105 54.49528  1.000 57.43535 ? 119 ARG D NE  1 
ATOM   3824 C CZ  . ARG D 4  105 ? -28.41301 -36.62339 54.53175  1.000 65.71986 ? 119 ARG D CZ  1 
ATOM   3825 N NH1 . ARG D 4  105 ? -28.03604 -37.78154 55.04892  1.000 58.28615 ? 119 ARG D NH1 1 
ATOM   3826 N NH2 . ARG D 4  105 ? -29.64190 -36.50065 54.03717  1.000 56.40947 ? 119 ARG D NH2 1 
ATOM   3827 N N   . LEU D 4  106 ? -25.94057 -31.50504 57.69248  1.000 20.75087 ? 120 LEU D N   1 
ATOM   3828 C CA  . LEU D 4  106 ? -26.80854 -31.06886 58.77848  1.000 24.17058 ? 120 LEU D CA  1 
ATOM   3829 C C   . LEU D 4  106 ? -28.21896 -31.59243 58.54558  1.000 23.69071 ? 120 LEU D C   1 
ATOM   3830 O O   . LEU D 4  106 ? -28.78275 -31.40793 57.46125  1.000 24.02440 ? 120 LEU D O   1 
ATOM   3831 C CB  . LEU D 4  106 ? -26.83036 -29.54211 58.88941  1.000 18.35078 ? 120 LEU D CB  1 
ATOM   3832 C CG  . LEU D 4  106 ? -27.89902 -28.97291 59.82836  1.000 22.07662 ? 120 LEU D CG  1 
ATOM   3833 C CD1 . LEU D 4  106 ? -27.63917 -29.40606 61.26639  1.000 20.13143 ? 120 LEU D CD1 1 
ATOM   3834 C CD2 . LEU D 4  106 ? -27.97891 -27.45604 59.72598  1.000 15.84171 ? 120 LEU D CD2 1 
ATOM   3835 N N   . LEU D 4  107 ? -28.78617 -32.23589 59.56482  1.000 24.75508 ? 121 LEU D N   1 
ATOM   3836 C CA  . LEU D 4  107 ? -30.14629 -32.76609 59.51787  1.000 25.34454 ? 121 LEU D CA  1 
ATOM   3837 C C   . LEU D 4  107 ? -30.93454 -32.16646 60.67544  1.000 28.58982 ? 121 LEU D C   1 
ATOM   3838 O O   . LEU D 4  107 ? -30.71755 -32.53345 61.83543  1.000 27.53839 ? 121 LEU D O   1 
ATOM   3839 C CB  . LEU D 4  107 ? -30.14326 -34.29275 59.58986  1.000 31.69457 ? 121 LEU D CB  1 
ATOM   3840 C CG  . LEU D 4  107 ? -29.51379 -35.03615 58.40896  1.000 42.14482 ? 121 LEU D CG  1 
ATOM   3841 C CD1 . LEU D 4  107 ? -29.63487 -36.54042 58.59575  1.000 48.47025 ? 121 LEU D CD1 1 
ATOM   3842 C CD2 . LEU D 4  107 ? -30.15218 -34.60449 57.09740  1.000 45.50240 ? 121 LEU D CD2 1 
ATOM   3843 N N   . VAL D 4  108 ? -31.84608 -31.25039 60.36434  1.000 26.71855 ? 122 VAL D N   1 
ATOM   3844 C CA  . VAL D 4  108 ? -32.65867 -30.58705 61.37838  1.000 23.32292 ? 122 VAL D CA  1 
ATOM   3845 C C   . VAL D 4  108 ? -33.96870 -31.35072 61.52904  1.000 27.28927 ? 122 VAL D C   1 
ATOM   3846 O O   . VAL D 4  108 ? -34.72243 -31.50788 60.56271  1.000 24.63806 ? 122 VAL D O   1 
ATOM   3847 C CB  . VAL D 4  108 ? -32.91299 -29.11646 61.01650  1.000 26.08121 ? 122 VAL D CB  1 
ATOM   3848 C CG1 . VAL D 4  108 ? -33.79839 -28.45822 62.06817  1.000 23.32701 ? 122 VAL D CG1 1 
ATOM   3849 C CG2 . VAL D 4  108 ? -31.59420 -28.36978 60.88096  1.000 22.77457 ? 122 VAL D CG2 1 
ATOM   3850 N N   . SER D 4  109 ? -34.24170 -31.81876 62.74556  1.000 24.75935 ? 123 SER D N   1 
ATOM   3851 C CA  . SER D 4  109 ? -35.34594 -32.64960 63.20488  1.000 28.18346 ? 123 SER D CA  1 
ATOM   3852 C C   . SER D 4  109 ? -36.45458 -31.80203 63.81666  1.000 24.94033 ? 123 SER D C   1 
ATOM   3853 O O   . SER D 4  109 ? -36.17453 -30.85896 64.56415  1.000 26.95755 ? 123 SER D O   1 
ATOM   3854 C CB  . SER D 4  109 ? -34.85608 -33.65731 64.24517  1.000 31.20082 ? 123 SER D CB  1 
ATOM   3855 O OG  . SER D 4  109 ? -34.49400 -34.88103 63.63150  1.000 39.83678 ? 123 SER D OG  1 
ATOM   3856 N N   . PRO D 4  110 ? -37.71631 -32.10367 63.51990  1.000 30.29447 ? 124 PRO D N   1 
ATOM   3857 C CA  . PRO D 4  110 ? -38.81303 -31.39886 64.18664  1.000 27.86636 ? 124 PRO D CA  1 
ATOM   3858 C C   . PRO D 4  110 ? -38.96619 -31.83449 65.63396  1.000 26.10842 ? 124 PRO D C   1 
ATOM   3859 O O   . PRO D 4  110 ? -38.64601 -32.96488 66.01050  1.000 21.11247 ? 124 PRO D O   1 
ATOM   3860 C CB  . PRO D 4  110 ? -40.03980 -31.79896 63.35930  1.000 27.04742 ? 124 PRO D CB  1 
ATOM   3861 C CG  . PRO D 4  110 ? -39.67132 -33.13428 62.80565  1.000 24.56275 ? 124 PRO D CG  1 
ATOM   3862 C CD  . PRO D 4  110 ? -38.21796 -32.98024 62.44952  1.000 27.32373 ? 124 PRO D CD  1 
ATOM   3863 N N   . ASN D 4  111 ? -39.46494 -30.91194 66.45049  1.000 25.18406 ? 125 ASN D N   1 
ATOM   3864 C CA  . ASN D 4  111 ? -39.83066 -31.22525 67.82568  1.000 28.97517 ? 125 ASN D CA  1 
ATOM   3865 C C   . ASN D 4  111 ? -41.25163 -31.77603 67.82209  1.000 28.32966 ? 125 ASN D C   1 
ATOM   3866 O O   . ASN D 4  111 ? -42.21555 -31.02827 67.62950  1.000 27.39788 ? 125 ASN D O   1 
ATOM   3867 C CB  . ASN D 4  111 ? -39.70842 -29.98687 68.70959  1.000 34.76109 ? 125 ASN D CB  1 
ATOM   3868 C CG  . ASN D 4  111 ? -38.32324 -29.36250 68.65198  1.000 40.61356 ? 125 ASN D CG  1 
ATOM   3869 O OD1 . ASN D 4  111 ? -37.31070 -30.06395 68.67300  1.000 39.58884 ? 125 ASN D OD1 1 
ATOM   3870 N ND2 . ASN D 4  111 ? -38.27389 -28.03703 68.57279  1.000 36.39206 ? 125 ASN D ND2 1 
ATOM   3871 N N   . ILE D 4  112 ? -41.38138 -33.08569 68.00706  1.000 24.67750 ? 126 ILE D N   1 
ATOM   3872 C CA  . ILE D 4  112 ? -42.67987 -33.74868 68.02224  1.000 27.43068 ? 126 ILE D CA  1 
ATOM   3873 C C   . ILE D 4  112 ? -43.21728 -33.67726 69.44710  1.000 30.44910 ? 126 ILE D C   1 
ATOM   3874 O O   . ILE D 4  112 ? -42.72614 -34.36930 70.34255  1.000 27.13507 ? 126 ILE D O   1 
ATOM   3875 C CB  . ILE D 4  112 ? -42.57658 -35.19741 67.53266  1.000 25.55332 ? 126 ILE D CB  1 
ATOM   3876 C CG1 . ILE D 4  112 ? -41.82328 -35.25413 66.20110  1.000 22.77982 ? 126 ILE D CG1 1 
ATOM   3877 C CG2 . ILE D 4  112 ? -43.96077 -35.81052 67.38978  1.000 25.80367 ? 126 ILE D CG2 1 
ATOM   3878 C CD1 . ILE D 4  112 ? -42.52515 -34.52716 65.07259  1.000 24.09101 ? 126 ILE D CD1 1 
ATOM   3879 N N   . GLN D 4  113 ? -44.23188 -32.83774 69.65755  1.000 32.49693 ? 127 GLN D N   1 
ATOM   3880 C CA  . GLN D 4  113 ? -44.72217 -32.59511 71.01073  1.000 43.30343 ? 127 GLN D CA  1 
ATOM   3881 C C   . GLN D 4  113 ? -45.49432 -33.79550 71.54807  1.000 40.49425 ? 127 GLN D C   1 
ATOM   3882 O O   . GLN D 4  113 ? -45.28582 -34.21684 72.69155  1.000 38.55832 ? 127 GLN D O   1 
ATOM   3883 C CB  . GLN D 4  113 ? -45.58755 -31.33467 71.03473  1.000 45.79392 ? 127 GLN D CB  1 
ATOM   3884 C CG  . GLN D 4  113 ? -44.78777 -30.04222 71.11468  1.000 49.81280 ? 127 GLN D CG  1 
ATOM   3885 C CD  . GLN D 4  113 ? -43.82236 -30.02447 72.28668  1.000 67.98258 ? 127 GLN D CD  1 
ATOM   3886 O OE1 . GLN D 4  113 ? -44.23473 -30.04222 73.44695  1.000 70.04282 ? 127 GLN D OE1 1 
ATOM   3887 N NE2 . GLN D 4  113 ? -42.52821 -29.99033 71.98715  1.000 64.81070 ? 127 GLN D NE2 1 
ATOM   3888 N N   . ASN D 4  114 ? -46.39307 -34.36239 70.73967  1.000 31.74416 ? 128 ASN D N   1 
ATOM   3889 C CA  . ASN D 4  114 ? -47.21056 -35.50798 71.13616  1.000 39.78176 ? 128 ASN D CA  1 
ATOM   3890 C C   . ASN D 4  114 ? -46.93721 -36.66082 70.17676  1.000 34.15702 ? 128 ASN D C   1 
ATOM   3891 O O   . ASN D 4  114 ? -47.69600 -36.87744 69.21970  1.000 31.44359 ? 128 ASN D O   1 
ATOM   3892 C CB  . ASN D 4  114 ? -48.69611 -35.15139 71.15863  1.000 36.75196 ? 128 ASN D CB  1 
ATOM   3893 C CG  . ASN D 4  114 ? -48.98520 -33.91291 71.98397  1.000 46.71564 ? 128 ASN D CG  1 
ATOM   3894 O OD1 . ASN D 4  114 ? -48.61162 -33.83153 73.15492  1.000 51.89511 ? 128 ASN D OD1 1 
ATOM   3895 N ND2 . ASN D 4  114 ? -49.65293 -32.93872 71.37558  1.000 50.67738 ? 128 ASN D ND2 1 
ATOM   3896 N N   . PRO D 4  115 ? -45.86874 -37.42526 70.40459  1.000 31.00451 ? 129 PRO D N   1 
ATOM   3897 C CA  . PRO D 4  115 ? -45.56212 -38.54669 69.50805  1.000 27.80344 ? 129 PRO D CA  1 
ATOM   3898 C C   . PRO D 4  115 ? -46.67016 -39.58927 69.52668  1.000 31.74176 ? 129 PRO D C   1 
ATOM   3899 O O   . PRO D 4  115 ? -47.27043 -39.86884 70.56608  1.000 31.63317 ? 129 PRO D O   1 
ATOM   3900 C CB  . PRO D 4  115 ? -44.25074 -39.10732 70.07333  1.000 30.08154 ? 129 PRO D CB  1 
ATOM   3901 C CG  . PRO D 4  115 ? -43.67864 -37.99452 70.90541  1.000 34.76107 ? 129 PRO D CG  1 
ATOM   3902 C CD  . PRO D 4  115 ? -44.86850 -37.28685 71.47608  1.000 30.95186 ? 129 PRO D CD  1 
ATOM   3903 N N   . ASP D 4  116 ? -46.93709 -40.16563 68.35493  1.000 28.58209 ? 130 ASP D N   1 
ATOM   3904 C CA  . ASP D 4  116 ? -48.00975 -41.14793 68.18278  1.000 26.26425 ? 130 ASP D CA  1 
ATOM   3905 C C   . ASP D 4  116 ? -47.52988 -42.26113 67.25748  1.000 28.55091 ? 130 ASP D C   1 
ATOM   3906 O O   . ASP D 4  116 ? -48.10551 -42.49624 66.19165  1.000 20.41367 ? 130 ASP D O   1 
ATOM   3907 C CB  . ASP D 4  116 ? -49.26512 -40.47080 67.63260  1.000 28.51233 ? 130 ASP D CB  1 
ATOM   3908 C CG  . ASP D 4  116 ? -50.52835 -41.26706 67.89615  1.000 35.37969 ? 130 ASP D CG  1 
ATOM   3909 O OD1 . ASP D 4  116 ? -50.43902 -42.36543 68.48353  1.000 31.65763 ? 130 ASP D OD1 1 
ATOM   3910 O OD2 . ASP D 4  116 ? -51.61539 -40.79054 67.50833  1.000 37.89919 ? 130 ASP D OD2 1 
ATOM   3911 N N   . PRO D 4  117 ? -46.48154 -42.98588 67.65316  1.000 27.87727 ? 131 PRO D N   1 
ATOM   3912 C CA  . PRO D 4  117 ? -45.84161 -43.92955 66.72360  1.000 21.79985 ? 131 PRO D CA  1 
ATOM   3913 C C   . PRO D 4  117 ? -46.79084 -45.04492 66.30720  1.000 25.79224 ? 131 PRO D C   1 
ATOM   3914 O O   . PRO D 4  117 ? -47.47153 -45.64963 67.13845  1.000 22.60679 ? 131 PRO D O   1 
ATOM   3915 C CB  . PRO D 4  117 ? -44.65422 -44.46770 67.52892  1.000 25.31395 ? 131 PRO D CB  1 
ATOM   3916 C CG  . PRO D 4  117 ? -45.06771 -44.30692 68.96024  1.000 24.04659 ? 131 PRO D CG  1 
ATOM   3917 C CD  . PRO D 4  117 ? -45.90789 -43.06473 69.00959  1.000 20.70587 ? 131 PRO D CD  1 
ATOM   3918 N N   . ALA D 4  118 ? -46.83053 -45.31349 65.00340  1.000 23.87877 ? 132 ALA D N   1 
ATOM   3919 C CA  . ALA D 4  118 ? -47.72307 -46.33053 64.46768  1.000 22.37516 ? 132 ALA D CA  1 
ATOM   3920 C C   . ALA D 4  118 ? -47.17611 -46.84342 63.14397  1.000 24.69388 ? 132 ALA D C   1 
ATOM   3921 O O   . ALA D 4  118 ? -46.50287 -46.11524 62.40964  1.000 25.35722 ? 132 ALA D O   1 
ATOM   3922 C CB  . ALA D 4  118 ? -49.14315 -45.78564 64.27785  1.000 23.75692 ? 132 ALA D CB  1 
ATOM   3923 N N   . VAL D 4  119 ? -47.47651 -48.10622 62.85100  1.000 26.24586 ? 133 VAL D N   1 
ATOM   3924 C CA  . VAL D 4  119 ? -47.14304 -48.73149 61.57569  1.000 24.09370 ? 133 VAL D CA  1 
ATOM   3925 C C   . VAL D 4  119 ? -48.45380 -49.11851 60.90396  1.000 25.97758 ? 133 VAL D C   1 
ATOM   3926 O O   . VAL D 4  119 ? -49.16177 -50.01659 61.37863  1.000 27.23818 ? 133 VAL D O   1 
ATOM   3927 C CB  . VAL D 4  119 ? -46.22977 -49.95165 61.74674  1.000 27.67284 ? 133 VAL D CB  1 
ATOM   3928 C CG1 . VAL D 4  119 ? -45.93402 -50.57819 60.39269  1.000 27.58798 ? 133 VAL D CG1 1 
ATOM   3929 C CG2 . VAL D 4  119 ? -44.93644 -49.55708 62.45265  1.000 24.65341 ? 133 VAL D CG2 1 
ATOM   3930 N N   . TYR D 4  120 ? -48.78017 -48.44350 59.80565  1.000 22.86745 ? 134 TYR D N   1 
ATOM   3931 C CA  . TYR D 4  120 ? -50.00914 -48.68285 59.06282  1.000 25.88765 ? 134 TYR D CA  1 
ATOM   3932 C C   . TYR D 4  120 ? -49.70455 -49.41375 57.76328  1.000 26.97328 ? 134 TYR D C   1 
ATOM   3933 O O   . TYR D 4  120 ? -48.76414 -49.05621 57.04686  1.000 24.12015 ? 134 TYR D O   1 
ATOM   3934 C CB  . TYR D 4  120 ? -50.72525 -47.37000 58.73128  1.000 21.96153 ? 134 TYR D CB  1 
ATOM   3935 C CG  . TYR D 4  120 ? -51.06634 -46.50276 59.91913  1.000 28.25813 ? 134 TYR D CG  1 
ATOM   3936 C CD1 . TYR D 4  120 ? -52.12371 -46.82561 60.75956  1.000 24.33590 ? 134 TYR D CD1 1 
ATOM   3937 C CD2 . TYR D 4  120 ? -50.34309 -45.34679 60.18742  1.000 25.55055 ? 134 TYR D CD2 1 
ATOM   3938 C CE1 . TYR D 4  120 ? -52.44411 -46.02805 61.84285  1.000 30.11440 ? 134 TYR D CE1 1 
ATOM   3939 C CE2 . TYR D 4  120 ? -50.65605 -44.54269 61.26489  1.000 25.85494 ? 134 TYR D CE2 1 
ATOM   3940 C CZ  . TYR D 4  120 ? -51.70743 -44.88753 62.08985  1.000 29.64857 ? 134 TYR D CZ  1 
ATOM   3941 O OH  . TYR D 4  120 ? -52.02102 -44.08883 63.16481  1.000 24.81064 ? 134 TYR D OH  1 
ATOM   3942 N N   . GLN D 4  121 ? -50.50535 -50.43015 57.45234  1.000 26.50593 ? 135 GLN D N   1 
ATOM   3943 C CA  . GLN D 4  121 ? -50.47924 -51.00575 56.11466  1.000 29.99376 ? 135 GLN D CA  1 
ATOM   3944 C C   . GLN D 4  121 ? -51.35017 -50.15631 55.20368  1.000 29.11357 ? 135 GLN D C   1 
ATOM   3945 O O   . GLN D 4  121 ? -52.56827 -50.07919 55.39486  1.000 29.48688 ? 135 GLN D O   1 
ATOM   3946 C CB  . GLN D 4  121 ? -50.96409 -52.45235 56.10319  1.000 34.40725 ? 135 GLN D CB  1 
ATOM   3947 C CG  . GLN D 4  121 ? -51.00616 -53.02275 54.68785  1.000 39.98287 ? 135 GLN D CG  1 
ATOM   3948 C CD  . GLN D 4  121 ? -50.67796 -54.49809 54.62348  1.000 41.79021 ? 135 GLN D CD  1 
ATOM   3949 O OE1 . GLN D 4  121 ? -50.35223 -55.11979 55.63368  1.000 55.51566 ? 135 GLN D OE1 1 
ATOM   3950 N NE2 . GLN D 4  121 ? -50.74492 -55.06472 53.42353  1.000 50.27148 ? 135 GLN D NE2 1 
ATOM   3951 N N   . LEU D 4  122 ? -50.72968 -49.51077 54.22510  1.000 23.84451 ? 136 LEU D N   1 
ATOM   3952 C CA  . LEU D 4  122 ? -51.49708 -48.71033 53.29123  1.000 30.84155 ? 136 LEU D CA  1 
ATOM   3953 C C   . LEU D 4  122 ? -52.30089 -49.61574 52.36578  1.000 25.25343 ? 136 LEU D C   1 
ATOM   3954 O O   . LEU D 4  122 ? -52.01999 -50.80899 52.21974  1.000 25.69515 ? 136 LEU D O   1 
ATOM   3955 C CB  . LEU D 4  122 ? -50.57728 -47.79814 52.48165  1.000 30.03653 ? 136 LEU D CB  1 
ATOM   3956 C CG  . LEU D 4  122 ? -50.41516 -46.38759 53.05180  1.000 32.92904 ? 136 LEU D CG  1 
ATOM   3957 C CD1 . LEU D 4  122 ? -49.84064 -46.42683 54.45649  1.000 22.81122 ? 136 LEU D CD1 1 
ATOM   3958 C CD2 . LEU D 4  122 ? -49.54366 -45.55122 52.14713  1.000 26.13732 ? 136 LEU D CD2 1 
ATOM   3959 N N   . ARG D 4  123 ? -53.32858 -49.03603 51.75327  1.000 23.10663 ? 137 ARG D N   1 
ATOM   3960 C CA  . ARG D 4  123 ? -54.11937 -49.77714 50.78360  1.000 27.74546 ? 137 ARG D CA  1 
ATOM   3961 C C   . ARG D 4  123 ? -53.23904 -50.18809 49.61366  1.000 26.60584 ? 137 ARG D C   1 
ATOM   3962 O O   . ARG D 4  123 ? -52.46926 -49.37863 49.08721  1.000 27.63891 ? 137 ARG D O   1 
ATOM   3963 C CB  . ARG D 4  123 ? -55.29392 -48.93053 50.29680  1.000 27.85087 ? 137 ARG D CB  1 
ATOM   3964 C CG  . ARG D 4  123 ? -56.36246 -48.69285 51.35017  1.000 34.07343 ? 137 ARG D CG  1 
ATOM   3965 C CD  . ARG D 4  123 ? -57.26855 -49.90430 51.49302  1.000 47.13777 ? 137 ARG D CD  1 
ATOM   3966 N NE  . ARG D 4  123 ? -58.20371 -49.76351 52.60270  1.000 56.86755 ? 137 ARG D NE  1 
ATOM   3967 C CZ  . ARG D 4  123 ? -59.51094 -49.59009 52.46248  1.000 65.95333 ? 137 ARG D CZ  1 
ATOM   3968 N NH1 . ARG D 4  123 ? -60.07484 -49.52197 51.26744  1.000 65.50242 ? 137 ARG D NH1 1 
ATOM   3969 N NH2 . ARG D 4  123 ? -60.27168 -49.48253 53.54839  1.000 60.14734 ? 137 ARG D NH2 1 
ATOM   3970 N N   . ASP D 4  124 ? -53.33181 -51.45887 49.23081  1.000 30.09859 ? 138 ASP D N   1 
ATOM   3971 C CA  . ASP D 4  124 ? -52.59212 -51.93867 48.07422  1.000 31.13280 ? 138 ASP D CA  1 
ATOM   3972 C C   . ASP D 4  124 ? -52.96540 -51.12569 46.84160  1.000 31.20940 ? 138 ASP D C   1 
ATOM   3973 O O   . ASP D 4  124 ? -54.10495 -50.67856 46.68470  1.000 25.75338 ? 138 ASP D O   1 
ATOM   3974 C CB  . ASP D 4  124 ? -52.88347 -53.42120 47.82439  1.000 31.39552 ? 138 ASP D CB  1 
ATOM   3975 C CG  . ASP D 4  124 ? -51.88965 -54.34239 48.51175  1.000 38.12059 ? 138 ASP D CG  1 
ATOM   3976 O OD1 . ASP D 4  124 ? -50.93854 -53.84022 49.14884  1.000 39.34387 ? 138 ASP D OD1 1 
ATOM   3977 O OD2 . ASP D 4  124 ? -52.06444 -55.57599 48.41615  1.000 35.90120 ? 138 ASP D OD2 1 
ATOM   3978 N N   . SER D 4  125 ? -51.98197 -50.91039 45.97550  1.000 31.36255 ? 139 SER D N   1 
ATOM   3979 C CA  . SER D 4  125 ? -52.25699 -50.36811 44.65626  1.000 32.37668 ? 139 SER D CA  1 
ATOM   3980 C C   . SER D 4  125 ? -52.69485 -51.49155 43.73084  1.000 35.21999 ? 139 SER D C   1 
ATOM   3981 O O   . SER D 4  125 ? -52.14339 -52.59871 43.76815  1.000 38.22901 ? 139 SER D O   1 
ATOM   3982 C CB  . SER D 4  125 ? -51.02569 -49.66457 44.08484  1.000 31.85093 ? 139 SER D CB  1 
ATOM   3983 O OG  . SER D 4  125 ? -51.19717 -49.36169 42.70740  1.000 32.06318 ? 139 SER D OG  1 
ATOM   3984 N N   . LYS D 4  126 ? -53.69621 -51.20047 42.89774  1.000 39.30787 ? 140 LYS D N   1 
ATOM   3985 C CA  . LYS D 4  126 ? -54.16510 -52.20565 41.96142  1.000 39.29087 ? 140 LYS D CA  1 
ATOM   3986 C C   . LYS D 4  126 ? -53.26241 -52.28758 40.73111  1.000 42.04349 ? 140 LYS D C   1 
ATOM   3987 O O   . LYS D 4  126 ? -53.39963 -53.21353 39.92417  1.000 50.98753 ? 140 LYS D O   1 
ATOM   3988 C CB  . LYS D 4  126 ? -55.63858 -51.95967 41.59594  1.000 43.31591 ? 140 LYS D CB  1 
ATOM   3989 C CG  . LYS D 4  126 ? -56.14060 -53.28067 41.06691  1.000 53.46645 ? 140 LYS D CG  1 
ATOM   3990 C CD  . LYS D 4  126 ? -57.44273 -53.77918 41.67961  1.000 57.41068 ? 140 LYS D CD  1 
ATOM   3991 C CE  . LYS D 4  126 ? -58.72122 -52.98119 41.48863  1.000 61.50218 ? 140 LYS D CE  1 
ATOM   3992 N NZ  . LYS D 4  126 ? -59.20866 -52.69326 40.12691  1.000 72.80879 ? 140 LYS D NZ  1 
ATOM   3993 N N   . SER D 4  127 ? -52.25812 -51.41678 40.64196  1.000 37.90220 ? 141 SER D N   1 
ATOM   3994 C CA  . SER D 4  127 ? -51.28626 -51.43273 39.55704  1.000 42.91875 ? 141 SER D CA  1 
ATOM   3995 C C   . SER D 4  127 ? -49.90371 -51.89752 40.01604  1.000 27.54921 ? 141 SER D C   1 
ATOM   3996 O O   . SER D 4  127 ? -48.89269 -51.53918 39.40501  1.000 48.13833 ? 141 SER D O   1 
ATOM   3997 C CB  . SER D 4  127 ? -51.18435 -50.04567 38.92721  1.000 47.42386 ? 141 SER D CB  1 
ATOM   3998 O OG  . SER D 4  127 ? -50.26870 -49.22839 39.63577  1.000 49.28474 ? 141 SER D OG  1 
ATOM   3999 N N   . SER D 4  128 ? -49.83576 -52.69531 41.08213  1.000 31.14252 ? 142 SER D N   1 
ATOM   4000 C CA  . SER D 4  128 ? -48.54973 -53.02984 41.68058  1.000 31.94194 ? 142 SER D CA  1 
ATOM   4001 C C   . SER D 4  128 ? -48.61350 -54.37220 42.39541  1.000 32.27985 ? 142 SER D C   1 
ATOM   4002 O O   . SER D 4  128 ? -49.61632 -54.69930 43.03501  1.000 34.95501 ? 142 SER D O   1 
ATOM   4003 C CB  . SER D 4  128 ? -48.10940 -51.94260 42.66746  1.000 30.54108 ? 142 SER D CB  1 
ATOM   4004 O OG  . SER D 4  128 ? -46.85008 -52.24666 43.23901  1.000 29.43570 ? 142 SER D OG  1 
ATOM   4005 N N   . ASP D 4  129 ? -47.52480 -55.13414 42.29585  1.000 25.24195 ? 143 ASP D N   1 
ATOM   4006 C CA  . ASP D 4  129 ? -47.35401 -56.36998 43.04959  1.000 32.67150 ? 143 ASP D CA  1 
ATOM   4007 C C   . ASP D 4  129 ? -46.80843 -56.13475 44.45505  1.000 36.60626 ? 143 ASP D C   1 
ATOM   4008 O O   . ASP D 4  129 ? -46.53023 -57.10558 45.16737  1.000 38.36905 ? 143 ASP D O   1 
ATOM   4009 C CB  . ASP D 4  129 ? -46.42345 -57.32388 42.29150  1.000 28.20861 ? 143 ASP D CB  1 
ATOM   4010 C CG  . ASP D 4  129 ? -45.02375 -56.75619 42.10908  1.000 42.75599 ? 143 ASP D CG  1 
ATOM   4011 O OD1 . ASP D 4  129 ? -44.86734 -55.51791 42.16793  1.000 41.30689 ? 143 ASP D OD1 1 
ATOM   4012 O OD2 . ASP D 4  129 ? -44.07840 -57.54773 41.90261  1.000 38.69921 ? 143 ASP D OD2 1 
ATOM   4013 N N   . LYS D 4  130 ? -46.65635 -54.88082 44.86998  1.000 32.56016 ? 144 LYS D N   1 
ATOM   4014 C CA  . LYS D 4  130 ? -45.98872 -54.53819 46.11561  1.000 30.71001 ? 144 LYS D CA  1 
ATOM   4015 C C   . LYS D 4  130 ? -46.99609 -54.10809 47.17531  1.000 32.11516 ? 144 LYS D C   1 
ATOM   4016 O O   . LYS D 4  130 ? -48.08708 -53.62304 46.86323  1.000 28.92004 ? 144 LYS D O   1 
ATOM   4017 C CB  . LYS D 4  130 ? -44.96588 -53.41968 45.89150  1.000 31.71634 ? 144 LYS D CB  1 
ATOM   4018 C CG  . LYS D 4  130 ? -43.62185 -53.90570 45.36761  1.000 36.65263 ? 144 LYS D CG  1 
ATOM   4019 C CD  . LYS D 4  130 ? -42.80375 -52.76537 44.78029  1.000 31.60716 ? 144 LYS D CD  1 
ATOM   4020 C CE  . LYS D 4  130 ? -43.23124 -52.44949 43.35720  1.000 41.58380 ? 144 LYS D CE  1 
ATOM   4021 N NZ  . LYS D 4  130 ? -42.70731 -53.44636 42.38134  1.000 43.12248 ? 144 LYS D NZ  1 
ATOM   4022 N N   . SER D 4  131 ? -46.61471 -54.29721 48.43663  1.000 33.08334 ? 145 SER D N   1 
ATOM   4023 C CA  . SER D 4  131 ? -47.38109 -53.83526 49.58523  1.000 31.53460 ? 145 SER D CA  1 
ATOM   4024 C C   . SER D 4  131 ? -46.52018 -52.87683 50.39664  1.000 30.53028 ? 145 SER D C   1 
ATOM   4025 O O   . SER D 4  131 ? -45.30486 -53.06403 50.50252  1.000 28.87449 ? 145 SER D O   1 
ATOM   4026 C CB  . SER D 4  131 ? -47.84014 -55.00990 50.45637  1.000 31.49510 ? 145 SER D CB  1 
ATOM   4027 O OG  . SER D 4  131 ? -48.83957 -55.77071 49.79661  1.000 36.80224 ? 145 SER D OG  1 
ATOM   4028 N N   . VAL D 4  132 ? -47.14928 -51.85316 50.97076  1.000 25.72184 ? 146 VAL D N   1 
ATOM   4029 C CA  . VAL D 4  132 ? -46.44289 -50.74614 51.60651  1.000 25.11149 ? 146 VAL D CA  1 
ATOM   4030 C C   . VAL D 4  132 ? -46.85497 -50.65665 53.07020  1.000 31.02746 ? 146 VAL D C   1 
ATOM   4031 O O   . VAL D 4  132 ? -48.05028 -50.68580 53.38822  1.000 20.46636 ? 146 VAL D O   1 
ATOM   4032 C CB  . VAL D 4  132 ? -46.72129 -49.41434 50.88548  1.000 23.20786 ? 146 VAL D CB  1 
ATOM   4033 C CG1 . VAL D 4  132 ? -46.19053 -48.24146 51.70045  1.000 28.62584 ? 146 VAL D CG1 1 
ATOM   4034 C CG2 . VAL D 4  132 ? -46.10855 -49.42634 49.50355  1.000 19.43428 ? 146 VAL D CG2 1 
ATOM   4035 N N   . CYS D 4  133 ? -45.86387 -50.53873 53.95252  1.000 20.30657 ? 147 CYS D N   1 
ATOM   4036 C CA  . CYS D 4  133 ? -46.07158 -50.26374 55.36804  1.000 25.40814 ? 147 CYS D CA  1 
ATOM   4037 C C   . CYS D 4  133 ? -45.49423 -48.89541 55.70824  1.000 31.69075 ? 147 CYS D C   1 
ATOM   4038 O O   . CYS D 4  133 ? -44.37688 -48.56480 55.29646  1.000 24.83634 ? 147 CYS D O   1 
ATOM   4039 C CB  . CYS D 4  133 ? -45.41144 -51.33337 56.24222  1.000 31.77089 ? 147 CYS D CB  1 
ATOM   4040 S SG  . CYS D 4  133 ? -46.02824 -53.00722 55.97896  1.000 40.68754 ? 147 CYS D SG  1 
ATOM   4041 N N   . LEU D 4  134 ? -46.24980 -48.10335 56.46820  1.000 23.45054 ? 148 LEU D N   1 
ATOM   4042 C CA  . LEU D 4  134 ? -45.85413 -46.73969 56.81210  1.000 22.39363 ? 148 LEU D CA  1 
ATOM   4043 C C   . LEU D 4  134 ? -45.65563 -46.62483 58.31866  1.000 24.77870 ? 148 LEU D C   1 
ATOM   4044 O O   . LEU D 4  134 ? -46.62021 -46.70614 59.08715  1.000 23.79022 ? 148 LEU D O   1 
ATOM   4045 C CB  . LEU D 4  134 ? -46.89020 -45.72909 56.32577  1.000 21.57580 ? 148 LEU D CB  1 
ATOM   4046 C CG  . LEU D 4  134 ? -46.58180 -44.26424 56.64187  1.000 24.45937 ? 148 LEU D CG  1 
ATOM   4047 C CD1 . LEU D 4  134 ? -45.52883 -43.70942 55.69121  1.000 26.37813 ? 148 LEU D CD1 1 
ATOM   4048 C CD2 . LEU D 4  134 ? -47.85161 -43.43415 56.58247  1.000 24.48357 ? 148 LEU D CD2 1 
ATOM   4049 N N   . PHE D 4  135 ? -44.40641 -46.42853 58.73067  1.000 22.06707 ? 149 PHE D N   1 
ATOM   4050 C CA  . PHE D 4  135 ? -44.06118 -46.11516 60.11204  1.000 20.00263 ? 149 PHE D CA  1 
ATOM   4051 C C   . PHE D 4  135 ? -43.98864 -44.59788 60.24267  1.000 23.52969 ? 149 PHE D C   1 
ATOM   4052 O O   . PHE D 4  135 ? -43.15332 -43.96133 59.59317  1.000 23.06393 ? 149 PHE D O   1 
ATOM   4053 C CB  . PHE D 4  135 ? -42.72737 -46.77093 60.47601  1.000 19.35940 ? 149 PHE D CB  1 
ATOM   4054 C CG  . PHE D 4  135 ? -42.25209 -46.48347 61.87744  1.000 29.09408 ? 149 PHE D CG  1 
ATOM   4055 C CD1 . PHE D 4  135 ? -43.14805 -46.36860 62.92936  1.000 18.87518 ? 149 PHE D CD1 1 
ATOM   4056 C CD2 . PHE D 4  135 ? -40.89687 -46.34143 62.14029  1.000 20.55088 ? 149 PHE D CD2 1 
ATOM   4057 C CE1 . PHE D 4  135 ? -42.70019 -46.11020 64.21559  1.000 26.08574 ? 149 PHE D CE1 1 
ATOM   4058 C CE2 . PHE D 4  135 ? -40.44379 -46.08313 63.42340  1.000 24.53022 ? 149 PHE D CE2 1 
ATOM   4059 C CZ  . PHE D 4  135 ? -41.34648 -45.96843 64.46216  1.000 21.76762 ? 149 PHE D CZ  1 
ATOM   4060 N N   . THR D 4  136 ? -44.86151 -44.01617 61.06602  1.000 19.06722 ? 150 THR D N   1 
ATOM   4061 C CA  . THR D 4  136 ? -45.01400 -42.56651 61.07902  1.000 20.56140 ? 150 THR D CA  1 
ATOM   4062 C C   . THR D 4  136 ? -45.35581 -42.07185 62.47931  1.000 22.79781 ? 150 THR D C   1 
ATOM   4063 O O   . THR D 4  136 ? -45.66868 -42.84959 63.38467  1.000 20.73058 ? 150 THR D O   1 
ATOM   4064 C CB  . THR D 4  136 ? -46.09355 -42.11175 60.08837  1.000 21.53339 ? 150 THR D CB  1 
ATOM   4065 O OG1 . THR D 4  136 ? -46.13810 -40.67996 60.04807  1.000 23.36666 ? 150 THR D OG1 1 
ATOM   4066 C CG2 . THR D 4  136 ? -47.45825 -42.64075 60.50820  1.000 21.42849 ? 150 THR D CG2 1 
ATOM   4067 N N   . ASP D 4  137 ? -45.28806 -40.74669 62.63371  1.000 20.69594 ? 151 ASP D N   1 
ATOM   4068 C CA  . ASP D 4  137 ? -45.66752 -40.01952 63.84474  1.000 26.36367 ? 151 ASP D CA  1 
ATOM   4069 C C   . ASP D 4  137 ? -44.80013 -40.37810 65.04947  1.000 27.06912 ? 151 ASP D C   1 
ATOM   4070 O O   . ASP D 4  137 ? -45.21148 -40.17623 66.19629  1.000 23.56046 ? 151 ASP D O   1 
ATOM   4071 C CB  . ASP D 4  137 ? -47.15207 -40.22472 64.17168  1.000 21.03207 ? 151 ASP D CB  1 
ATOM   4072 C CG  . ASP D 4  137 ? -48.06663 -39.61285 63.12358  1.000 27.94365 ? 151 ASP D CG  1 
ATOM   4073 O OD1 . ASP D 4  137 ? -47.60688 -38.71582 62.38526  1.000 29.88826 ? 151 ASP D OD1 1 
ATOM   4074 O OD2 . ASP D 4  137 ? -49.24139 -40.02903 63.03266  1.000 29.10178 ? 151 ASP D OD2 1 
ATOM   4075 N N   . PHE D 4  138 ? -43.59518 -40.88646 64.81997  1.000 24.57326 ? 152 PHE D N   1 
ATOM   4076 C CA  . PHE D 4  138 ? -42.69257 -41.19618 65.91595  1.000 22.77790 ? 152 PHE D CA  1 
ATOM   4077 C C   . PHE D 4  138 ? -41.83478 -39.98304 66.26288  1.000 25.96614 ? 152 PHE D C   1 
ATOM   4078 O O   . PHE D 4  138 ? -41.73880 -39.01617 65.50239  1.000 22.84586 ? 152 PHE D O   1 
ATOM   4079 C CB  . PHE D 4  138 ? -41.80283 -42.39531 65.57533  1.000 25.77113 ? 152 PHE D CB  1 
ATOM   4080 C CG  . PHE D 4  138 ? -41.11719 -42.29577 64.23801  1.000 29.11805 ? 152 PHE D CG  1 
ATOM   4081 C CD1 . PHE D 4  138 ? -41.71930 -42.79882 63.09492  1.000 23.55806 ? 152 PHE D CD1 1 
ATOM   4082 C CD2 . PHE D 4  138 ? -39.86068 -41.72075 64.12897  1.000 25.17913 ? 152 PHE D CD2 1 
ATOM   4083 C CE1 . PHE D 4  138 ? -41.08683 -42.71985 61.86573  1.000 26.31330 ? 152 PHE D CE1 1 
ATOM   4084 C CE2 . PHE D 4  138 ? -39.22288 -41.63835 62.90397  1.000 27.30935 ? 152 PHE D CE2 1 
ATOM   4085 C CZ  . PHE D 4  138 ? -39.83745 -42.13810 61.77021  1.000 29.11148 ? 152 PHE D CZ  1 
ATOM   4086 N N   . ASP D 4  139 ? -41.21714 -40.04422 67.43900  1.000 21.39786 ? 153 ASP D N   1 
ATOM   4087 C CA  . ASP D 4  139 ? -40.35808 -38.96258 67.89494  1.000 26.61080 ? 153 ASP D CA  1 
ATOM   4088 C C   . ASP D 4  139 ? -39.05580 -38.93589 67.09989  1.000 21.61198 ? 153 ASP D C   1 
ATOM   4089 O O   . ASP D 4  139 ? -38.59041 -39.95682 66.58697  1.000 23.01382 ? 153 ASP D O   1 
ATOM   4090 C CB  . ASP D 4  139 ? -40.06097 -39.11230 69.38790  1.000 28.83593 ? 153 ASP D CB  1 
ATOM   4091 C CG  . ASP D 4  139 ? -39.20951 -37.98191 69.92835  1.000 33.08403 ? 153 ASP D CG  1 
ATOM   4092 O OD1 . ASP D 4  139 ? -39.76914 -36.90754 70.23477  1.000 35.05871 ? 153 ASP D OD1 1 
ATOM   4093 O OD2 . ASP D 4  139 ? -37.97848 -38.16584 70.03521  1.000 37.83742 ? 153 ASP D OD2 1 
ATOM   4094 N N   . SER D 4  140 ? -38.46066 -37.74397 67.01477  1.000 24.70291 ? 154 SER D N   1 
ATOM   4095 C CA  . SER D 4  140 ? -37.25001 -37.54941 66.22420  1.000 28.10301 ? 154 SER D CA  1 
ATOM   4096 C C   . SER D 4  140 ? -36.05383 -38.33110 66.75558  1.000 27.03370 ? 154 SER D C   1 
ATOM   4097 O O   . SER D 4  140 ? -35.07275 -38.50545 66.02487  1.000 25.87313 ? 154 SER D O   1 
ATOM   4098 C CB  . SER D 4  140 ? -36.91014 -36.06184 66.16300  1.000 32.30041 ? 154 SER D CB  1 
ATOM   4099 O OG  . SER D 4  140 ? -37.84322 -35.37040 65.34892  1.000 25.97869 ? 154 SER D OG  1 
ATOM   4100 N N   . GLN D 4  141 ? -36.10054 -38.80035 68.00325  1.000 28.07666 ? 155 GLN D N   1 
ATOM   4101 C CA  . GLN D 4  141 ? -34.99748 -39.59225 68.53443  1.000 28.82067 ? 155 GLN D CA  1 
ATOM   4102 C C   . GLN D 4  141 ? -34.99165 -41.01878 68.00190  1.000 27.94031 ? 155 GLN D C   1 
ATOM   4103 O O   . GLN D 4  141 ? -33.97926 -41.71349 68.13990  1.000 25.53453 ? 155 GLN D O   1 
ATOM   4104 C CB  . GLN D 4  141 ? -35.04745 -39.61512 70.06461  1.000 30.95468 ? 155 GLN D CB  1 
ATOM   4105 N N   . THR D 4  142 ? -36.08979 -41.46715 67.39991  1.000 27.55492 ? 156 THR D N   1 
ATOM   4106 C CA  . THR D 4  142 ? -36.15705 -42.82060 66.86605  1.000 32.27389 ? 156 THR D CA  1 
ATOM   4107 C C   . THR D 4  142 ? -35.30870 -42.93607 65.60508  1.000 32.50257 ? 156 THR D C   1 
ATOM   4108 O O   . THR D 4  142 ? -35.37391 -42.07946 64.71833  1.000 32.65034 ? 156 THR D O   1 
ATOM   4109 C CB  . THR D 4  142 ? -37.60701 -43.19973 66.56188  1.000 32.45387 ? 156 THR D CB  1 
ATOM   4110 O OG1 . THR D 4  142 ? -38.40689 -43.03318 67.74039  1.000 32.04002 ? 156 THR D OG1 1 
ATOM   4111 C CG2 . THR D 4  142 ? -37.69499 -44.64564 66.09341  1.000 28.58249 ? 156 THR D CG2 1 
ATOM   4112 N N   . ASN D 4  143 ? -34.50982 -43.99633 65.52879  1.000 34.29383 ? 157 ASN D N   1 
ATOM   4113 C CA  . ASN D 4  143 ? -33.68392 -44.28446 64.36617  1.000 42.36472 ? 157 ASN D CA  1 
ATOM   4114 C C   . ASN D 4  143 ? -34.26145 -45.47390 63.61092  1.000 40.50892 ? 157 ASN D C   1 
ATOM   4115 O O   . ASN D 4  143 ? -34.68833 -46.45998 64.21956  1.000 34.58079 ? 157 ASN D O   1 
ATOM   4116 C CB  . ASN D 4  143 ? -32.23744 -44.57684 64.77666  1.000 43.61327 ? 157 ASN D CB  1 
ATOM   4117 C CG  . ASN D 4  143 ? -31.47222 -43.32193 65.15156  1.000 50.26481 ? 157 ASN D CG  1 
ATOM   4118 O OD1 . ASN D 4  143 ? -31.70133 -42.24955 64.59164  1.000 56.94590 ? 157 ASN D OD1 1 
ATOM   4119 N ND2 . ASN D 4  143 ? -30.55575 -43.45071 66.10350  1.000 56.81993 ? 157 ASN D ND2 1 
ATOM   4120 N N   . VAL D 4  144 ? -34.27417 -45.37844 62.28539  1.000 36.59778 ? 158 VAL D N   1 
ATOM   4121 C CA  . VAL D 4  144 ? -34.79583 -46.43462 61.42616  1.000 31.10897 ? 158 VAL D CA  1 
ATOM   4122 C C   . VAL D 4  144 ? -33.61689 -47.15869 60.79123  1.000 42.48986 ? 158 VAL D C   1 
ATOM   4123 O O   . VAL D 4  144 ? -32.77516 -46.53557 60.13278  1.000 35.29458 ? 158 VAL D O   1 
ATOM   4124 C CB  . VAL D 4  144 ? -35.74327 -45.87251 60.35515  1.000 34.29793 ? 158 VAL D CB  1 
ATOM   4125 C CG1 . VAL D 4  144 ? -36.18263 -46.97722 59.40612  1.000 34.02002 ? 158 VAL D CG1 1 
ATOM   4126 C CG2 . VAL D 4  144 ? -36.94722 -45.21260 61.00780  1.000 27.97545 ? 158 VAL D CG2 1 
ATOM   4127 N N   . SER D 4  145 ? -33.55352 -48.47107 60.98688  1.000 38.68951 ? 159 SER D N   1 
ATOM   4128 C CA  . SER D 4  145 ? -32.48226 -49.27643 60.42524  1.000 35.24603 ? 159 SER D CA  1 
ATOM   4129 C C   . SER D 4  145 ? -32.91028 -49.88526 59.09267  1.000 42.06797 ? 159 SER D C   1 
ATOM   4130 O O   . SER D 4  145 ? -34.09180 -49.92308 58.74176  1.000 42.42049 ? 159 SER D O   1 
ATOM   4131 C CB  . SER D 4  145 ? -32.06528 -50.37508 61.40365  1.000 37.88731 ? 159 SER D CB  1 
ATOM   4132 O OG  . SER D 4  145 ? -31.79553 -49.84095 62.68777  1.000 43.78266 ? 159 SER D OG  1 
ATOM   4133 N N   . GLN D 4  146 ? -31.92224 -50.36793 58.34604  1.000 43.67482 ? 160 GLN D N   1 
ATOM   4134 C CA  . GLN D 4  146 ? -32.17598 -50.99209 57.05786  1.000 41.26368 ? 160 GLN D CA  1 
ATOM   4135 C C   . GLN D 4  146 ? -32.57230 -52.45242 57.24415  1.000 41.31760 ? 160 GLN D C   1 
ATOM   4136 O O   . GLN D 4  146 ? -32.22594 -53.09175 58.24181  1.000 44.75791 ? 160 GLN D O   1 
ATOM   4137 C CB  . GLN D 4  146 ? -30.94146 -50.88453 56.16203  1.000 48.96051 ? 160 GLN D CB  1 
ATOM   4138 C CG  . GLN D 4  146 ? -31.22880 -51.03086 54.67670  1.000 65.84048 ? 160 GLN D CG  1 
ATOM   4139 C CD  . GLN D 4  146 ? -32.26601 -50.04075 54.18230  1.000 60.71815 ? 160 GLN D CD  1 
ATOM   4140 O OE1 . GLN D 4  146 ? -32.15577 -48.83670 54.41768  1.000 58.72051 ? 160 GLN D OE1 1 
ATOM   4141 N NE2 . GLN D 4  146 ? -33.27994 -50.54509 53.48707  1.000 53.82550 ? 160 GLN D NE2 1 
ATOM   4142 N N   . SER D 4  147 ? -33.30814 -52.97674 56.26838  1.000 43.67778 ? 161 SER D N   1 
ATOM   4143 C CA  . SER D 4  147 ? -33.85805 -54.31927 56.38205  1.000 48.74293 ? 161 SER D CA  1 
ATOM   4144 C C   . SER D 4  147 ? -32.77800 -55.37849 56.19074  1.000 48.57622 ? 161 SER D C   1 
ATOM   4145 O O   . SER D 4  147 ? -31.82184 -55.19937 55.43158  1.000 48.95119 ? 161 SER D O   1 
ATOM   4146 C CB  . SER D 4  147 ? -34.97223 -54.52773 55.35671  1.000 53.80779 ? 161 SER D CB  1 
ATOM   4147 O OG  . SER D 4  147 ? -35.53589 -55.82256 55.47699  1.000 54.52421 ? 161 SER D OG  1 
ATOM   4148 N N   . LYS D 4  148 ? -32.94548 -56.49957 56.89498  1.000 51.66790 ? 162 LYS D N   1 
ATOM   4149 C CA  . LYS D 4  148 ? -32.04103 -57.63020 56.72241  1.000 55.26686 ? 162 LYS D CA  1 
ATOM   4150 C C   . LYS D 4  148 ? -32.42469 -58.46743 55.50837  1.000 58.04599 ? 162 LYS D C   1 
ATOM   4151 O O   . LYS D 4  148 ? -31.55219 -58.88119 54.73661  1.000 72.81338 ? 162 LYS D O   1 
ATOM   4152 C CB  . LYS D 4  148 ? -32.03085 -58.49321 57.98459  1.000 52.23274 ? 162 LYS D CB  1 
ATOM   4153 N N   . ASP D 4  149 ? -33.71856 -58.72366 55.32418  1.000 58.43445 ? 163 ASP D N   1 
ATOM   4154 C CA  . ASP D 4  149 ? -34.17887 -59.48049 54.16790  1.000 56.75393 ? 163 ASP D CA  1 
ATOM   4155 C C   . ASP D 4  149 ? -33.93683 -58.68591 52.89071  1.000 55.92028 ? 163 ASP D C   1 
ATOM   4156 O O   . ASP D 4  149 ? -34.33124 -57.52026 52.78749  1.000 55.84799 ? 163 ASP D O   1 
ATOM   4157 C CB  . ASP D 4  149 ? -35.66202 -59.81797 54.31081  1.000 49.55323 ? 163 ASP D CB  1 
ATOM   4158 N N   . SER D 4  150 ? -33.28564 -59.32205 51.91410  1.000 51.95832 ? 164 SER D N   1 
ATOM   4159 C CA  . SER D 4  150 ? -32.95917 -58.65713 50.65805  1.000 54.73779 ? 164 SER D CA  1 
ATOM   4160 C C   . SER D 4  150 ? -34.18699 -58.34284 49.81296  1.000 52.02335 ? 164 SER D C   1 
ATOM   4161 O O   . SER D 4  150 ? -34.06327 -57.61463 48.82220  1.000 47.26483 ? 164 SER D O   1 
ATOM   4162 C CB  . SER D 4  150 ? -31.98501 -59.51630 49.84890  1.000 50.57183 ? 164 SER D CB  1 
ATOM   4163 N N   . ASP D 4  151 ? -35.35741 -58.86629 50.17178  1.000 45.13507 ? 165 ASP D N   1 
ATOM   4164 C CA  . ASP D 4  151 ? -36.58568 -58.61749 49.43141  1.000 48.80517 ? 165 ASP D CA  1 
ATOM   4165 C C   . ASP D 4  151 ? -37.47675 -57.57970 50.10256  1.000 48.91148 ? 165 ASP D C   1 
ATOM   4166 O O   . ASP D 4  151 ? -38.61596 -57.38312 49.66825  1.000 38.04456 ? 165 ASP D O   1 
ATOM   4167 C CB  . ASP D 4  151 ? -37.35646 -59.92467 49.23909  1.000 51.11314 ? 165 ASP D CB  1 
ATOM   4168 C CG  . ASP D 4  151 ? -36.60049 -60.92523 48.38726  1.000 59.64953 ? 165 ASP D CG  1 
ATOM   4169 O OD1 . ASP D 4  151 ? -36.00838 -60.51225 47.36745  1.000 59.01307 ? 165 ASP D OD1 1 
ATOM   4170 O OD2 . ASP D 4  151 ? -36.59493 -62.12379 48.73980  1.000 62.43277 ? 165 ASP D OD2 1 
ATOM   4171 N N   . VAL D 4  152 ? -36.98848 -56.91753 51.14895  1.000 39.82945 ? 166 VAL D N   1 
ATOM   4172 C CA  . VAL D 4  152 ? -37.72294 -55.86834 51.84580  1.000 35.23911 ? 166 VAL D CA  1 
ATOM   4173 C C   . VAL D 4  152 ? -36.89849 -54.59137 51.77660  1.000 35.32550 ? 166 VAL D C   1 
ATOM   4174 O O   . VAL D 4  152 ? -35.70486 -54.59988 52.09841  1.000 33.73755 ? 166 VAL D O   1 
ATOM   4175 C CB  . VAL D 4  152 ? -38.01831 -56.25230 53.30723  1.000 35.63387 ? 166 VAL D CB  1 
ATOM   4176 C CG1 . VAL D 4  152 ? -38.78702 -55.13892 54.00417  1.000 33.45805 ? 166 VAL D CG1 1 
ATOM   4177 C CG2 . VAL D 4  152 ? -38.78996 -57.56198 53.36727  1.000 36.44956 ? 166 VAL D CG2 1 
ATOM   4178 N N   . TYR D 4  153 ? -37.53200 -53.49874 51.35871  1.000 30.63905 ? 167 TYR D N   1 
ATOM   4179 C CA  . TYR D 4  153 ? -36.85277 -52.22582 51.15026  1.000 28.55647 ? 167 TYR D CA  1 
ATOM   4180 C C   . TYR D 4  153 ? -37.40717 -51.19889 52.12547  1.000 29.47212 ? 167 TYR D C   1 
ATOM   4181 O O   . TYR D 4  153 ? -38.61937 -50.96388 52.16269  1.000 26.20301 ? 167 TYR D O   1 
ATOM   4182 C CB  . TYR D 4  153 ? -37.01817 -51.75512 49.70441  1.000 29.69742 ? 167 TYR D CB  1 
ATOM   4183 C CG  . TYR D 4  153 ? -36.52226 -52.76976 48.70080  1.000 36.06357 ? 167 TYR D CG  1 
ATOM   4184 C CD1 . TYR D 4  153 ? -35.18289 -52.81676 48.34050  1.000 34.67146 ? 167 TYR D CD1 1 
ATOM   4185 C CD2 . TYR D 4  153 ? -37.38800 -53.69438 48.13002  1.000 33.35629 ? 167 TYR D CD2 1 
ATOM   4186 C CE1 . TYR D 4  153 ? -34.72002 -53.74719 47.43219  1.000 40.90781 ? 167 TYR D CE1 1 
ATOM   4187 C CE2 . TYR D 4  153 ? -36.93346 -54.63081 47.21977  1.000 39.56573 ? 167 TYR D CE2 1 
ATOM   4188 C CZ  . TYR D 4  153 ? -35.59754 -54.65133 46.87483  1.000 41.42817 ? 167 TYR D CZ  1 
ATOM   4189 O OH  . TYR D 4  153 ? -35.13359 -55.57762 45.96986  1.000 46.78210 ? 167 TYR D OH  1 
ATOM   4190 N N   . ILE D 4  154 ? -36.52077 -50.59022 52.90846  1.000 30.62788 ? 168 ILE D N   1 
ATOM   4191 C CA  . ILE D 4  154 ? -36.89096 -49.60592 53.91721  1.000 28.86894 ? 168 ILE D CA  1 
ATOM   4192 C C   . ILE D 4  154 ? -36.17321 -48.30207 53.60227  1.000 33.89236 ? 168 ILE D C   1 
ATOM   4193 O O   . ILE D 4  154 ? -34.95124 -48.29060 53.41356  1.000 31.68101 ? 168 ILE D O   1 
ATOM   4194 C CB  . ILE D 4  154 ? -36.54606 -50.09144 55.33667  1.000 29.93001 ? 168 ILE D CB  1 
ATOM   4195 C CG1 . ILE D 4  154 ? -37.17447 -51.46256 55.59807  1.000 31.51458 ? 168 ILE D CG1 1 
ATOM   4196 C CG2 . ILE D 4  154 ? -37.00537 -49.07698 56.37320  1.000 29.16938 ? 168 ILE D CG2 1 
ATOM   4197 C CD1 . ILE D 4  154 ? -37.07322 -51.92010 57.03916  1.000 29.45728 ? 168 ILE D CD1 1 
ATOM   4198 N N   . THR D 4  155 ? -36.93098 -47.21028 53.54416  1.000 28.71482 ? 169 THR D N   1 
ATOM   4199 C CA  . THR D 4  155 ? -36.35499 -45.90179 53.28502  1.000 32.86113 ? 169 THR D CA  1 
ATOM   4200 C C   . THR D 4  155 ? -35.79192 -45.29961 54.56896  1.000 40.28559 ? 169 THR D C   1 
ATOM   4201 O O   . THR D 4  155 ? -35.99422 -45.80901 55.67482  1.000 38.91064 ? 169 THR D O   1 
ATOM   4202 C CB  . THR D 4  155 ? -37.39833 -44.95336 52.69605  1.000 33.48756 ? 169 THR D CB  1 
ATOM   4203 O OG1 . THR D 4  155 ? -38.41243 -44.69209 53.67557  1.000 42.26230 ? 169 THR D OG1 1 
ATOM   4204 C CG2 . THR D 4  155 ? -38.03768 -45.56350 51.46840  1.000 33.18466 ? 169 THR D CG2 1 
ATOM   4205 N N   . ASP D 4  156 ? -35.07493 -44.19296 54.40831  1.000 36.34326 ? 170 ASP D N   1 
ATOM   4206 C CA  . ASP D 4  156 ? -34.65294 -43.40994 55.55370  1.000 36.93412 ? 170 ASP D CA  1 
ATOM   4207 C C   . ASP D 4  156 ? -35.81340 -42.55584 56.05630  1.000 35.64822 ? 170 ASP D C   1 
ATOM   4208 O O   . ASP D 4  156 ? -36.83752 -42.38748 55.38950  1.000 29.52914 ? 170 ASP D O   1 
ATOM   4209 C CB  . ASP D 4  156 ? -33.45803 -42.52824 55.19559  1.000 42.93973 ? 170 ASP D CB  1 
ATOM   4210 C CG  . ASP D 4  156 ? -32.19410 -43.32872 54.95189  1.000 58.84553 ? 170 ASP D CG  1 
ATOM   4211 O OD1 . ASP D 4  156 ? -32.07354 -44.44054 55.50939  1.000 66.53154 ? 170 ASP D OD1 1 
ATOM   4212 O OD2 . ASP D 4  156 ? -31.32048 -42.84459 54.20194  1.000 62.61023 ? 170 ASP D OD2 1 
ATOM   4213 N N   . LYS D 4  157 ? -35.64043 -42.01286 57.25428  1.000 36.14422 ? 171 LYS D N   1 
ATOM   4214 C CA  . LYS D 4  157 ? -36.65779 -41.15771 57.84321  1.000 32.64159 ? 171 LYS D CA  1 
ATOM   4215 C C   . LYS D 4  157 ? -36.76500 -39.84145 57.07936  1.000 28.46530 ? 171 LYS D C   1 
ATOM   4216 O O   . LYS D 4  157 ? -35.75753 -39.23428 56.70612  1.000 29.61228 ? 171 LYS D O   1 
ATOM   4217 C CB  . LYS D 4  157 ? -36.32859 -40.91238 59.31318  1.000 33.81438 ? 171 LYS D CB  1 
ATOM   4218 C CG  . LYS D 4  157 ? -36.86873 -39.62888 59.88341  1.000 39.80309 ? 171 LYS D CG  1 
ATOM   4219 C CD  . LYS D 4  157 ? -35.99202 -39.19018 61.03229  1.000 44.22776 ? 171 LYS D CD  1 
ATOM   4220 C CE  . LYS D 4  157 ? -36.09818 -37.70607 61.26555  1.000 46.51992 ? 171 LYS D CE  1 
ATOM   4221 N NZ  . LYS D 4  157 ? -35.94461 -37.39632 62.71325  1.000 38.24605 ? 171 LYS D NZ  1 
ATOM   4222 N N   . CYS D 4  158 ? -38.00275 -39.41143 56.83749  1.000 22.40352 ? 172 CYS D N   1 
ATOM   4223 C CA  . CYS D 4  158 ? -38.30128 -38.19526 56.09607  1.000 27.54516 ? 172 CYS D CA  1 
ATOM   4224 C C   . CYS D 4  158 ? -39.19749 -37.30635 56.94699  1.000 27.12387 ? 172 CYS D C   1 
ATOM   4225 O O   . CYS D 4  158 ? -40.02884 -37.79618 57.71643  1.000 27.64163 ? 172 CYS D O   1 
ATOM   4226 C CB  . CYS D 4  158 ? -38.99528 -38.51779 54.75590  1.000 37.29297 ? 172 CYS D CB  1 
ATOM   4227 S SG  . CYS D 4  158 ? -38.57252 -37.45352 53.34673  1.000 48.82582 ? 172 CYS D SG  1 
ATOM   4228 N N   . VAL D 4  159 ? -39.02916 -35.99480 56.80302  1.000 27.80502 ? 173 VAL D N   1 
ATOM   4229 C CA  . VAL D 4  159 ? -39.79348 -35.01273 57.56602  1.000 27.90804 ? 173 VAL D CA  1 
ATOM   4230 C C   . VAL D 4  159 ? -40.68720 -34.24013 56.60670  1.000 24.80936 ? 173 VAL D C   1 
ATOM   4231 O O   . VAL D 4  159 ? -40.19279 -33.54345 55.71248  1.000 26.34793 ? 173 VAL D O   1 
ATOM   4232 C CB  . VAL D 4  159 ? -38.87810 -34.05224 58.33985  1.000 30.31015 ? 173 VAL D CB  1 
ATOM   4233 C CG1 . VAL D 4  159 ? -39.71635 -33.11086 59.19174  1.000 28.26300 ? 173 VAL D CG1 1 
ATOM   4234 C CG2 . VAL D 4  159 ? -37.88695 -34.82704 59.19534  1.000 31.96417 ? 173 VAL D CG2 1 
ATOM   4235 N N   . LEU D 4  160 ? -41.99829 -34.34459 56.79858  1.000 24.48138 ? 174 LEU D N   1 
ATOM   4236 C CA  . LEU D 4  160 ? -42.94974 -33.54658 56.04275  1.000 26.63169 ? 174 LEU D CA  1 
ATOM   4237 C C   . LEU D 4  160 ? -43.55018 -32.47234 56.94067  1.000 31.07553 ? 174 LEU D C   1 
ATOM   4238 O O   . LEU D 4  160 ? -43.63529 -32.63240 58.16245  1.000 27.58224 ? 174 LEU D O   1 
ATOM   4239 C CB  . LEU D 4  160 ? -44.05334 -34.41783 55.42536  1.000 28.68227 ? 174 LEU D CB  1 
ATOM   4240 C CG  . LEU D 4  160 ? -45.08036 -35.14432 56.29611  1.000 33.49589 ? 174 LEU D CG  1 
ATOM   4241 C CD1 . LEU D 4  160 ? -46.30987 -34.28314 56.54305  1.000 31.49680 ? 174 LEU D CD1 1 
ATOM   4242 C CD2 . LEU D 4  160 ? -45.47711 -36.45372 55.63058  1.000 30.37609 ? 174 LEU D CD2 1 
ATOM   4243 N N   . ASP D 4  161 ? -43.96351 -31.37078 56.31745  1.000 30.18713 ? 175 ASP D N   1 
ATOM   4244 C CA  . ASP D 4  161 ? -44.44749 -30.19026 57.02623  1.000 30.66671 ? 175 ASP D CA  1 
ATOM   4245 C C   . ASP D 4  161 ? -45.77936 -29.76996 56.41897  1.000 34.11467 ? 175 ASP D C   1 
ATOM   4246 O O   . ASP D 4  161 ? -45.82051 -29.26648 55.29180  1.000 30.82365 ? 175 ASP D O   1 
ATOM   4247 C CB  . ASP D 4  161 ? -43.42364 -29.05482 56.94888  1.000 36.09680 ? 175 ASP D CB  1 
ATOM   4248 C CG  . ASP D 4  161 ? -43.86284 -27.81010 57.70053  1.000 45.20646 ? 175 ASP D CG  1 
ATOM   4249 O OD1 . ASP D 4  161 ? -44.87360 -27.86854 58.43232  1.000 44.46145 ? 175 ASP D OD1 1 
ATOM   4250 O OD2 . ASP D 4  161 ? -43.18762 -26.76818 57.56177  1.000 44.71048 ? 175 ASP D OD2 1 
ATOM   4251 N N   . MET D 4  162 ? -46.86406 -29.97614 57.16511  1.000 36.47752 ? 176 MET D N   1 
ATOM   4252 C CA  . MET D 4  162 ? -48.19463 -29.52161 56.76155  1.000 34.46744 ? 176 MET D CA  1 
ATOM   4253 C C   . MET D 4  162 ? -48.33933 -28.07672 57.22251  1.000 40.07769 ? 176 MET D C   1 
ATOM   4254 O O   . MET D 4  162 ? -48.72030 -27.79793 58.36022  1.000 42.20378 ? 176 MET D O   1 
ATOM   4255 C CB  . MET D 4  162 ? -49.27301 -30.42199 57.35038  1.000 33.48485 ? 176 MET D CB  1 
ATOM   4256 C CG  . MET D 4  162 ? -49.17487 -31.87819 56.91643  1.000 26.94316 ? 176 MET D CG  1 
ATOM   4257 S SD  . MET D 4  162 ? -50.45030 -32.91036 57.66935  1.000 39.35178 ? 176 MET D SD  1 
ATOM   4258 C CE  . MET D 4  162 ? -51.83035 -32.57906 56.57782  1.000 26.80769 ? 176 MET D CE  1 
ATOM   4259 N N   . ARG D 4  163 ? -48.03170 -27.14188 56.31914  1.000 40.38183 ? 177 ARG D N   1 
ATOM   4260 C CA  . ARG D 4  163 ? -47.91395 -25.74010 56.71048  1.000 47.18842 ? 177 ARG D CA  1 
ATOM   4261 C C   . ARG D 4  163 ? -49.25863 -25.12488 57.07890  1.000 47.86185 ? 177 ARG D C   1 
ATOM   4262 O O   . ARG D 4  163 ? -49.32004 -24.27703 57.97657  1.000 56.97384 ? 177 ARG D O   1 
ATOM   4263 C CB  . ARG D 4  163 ? -47.25379 -24.93875 55.58925  1.000 49.16406 ? 177 ARG D CB  1 
ATOM   4264 C CG  . ARG D 4  163 ? -45.90555 -25.48816 55.15586  1.000 52.67090 ? 177 ARG D CG  1 
ATOM   4265 C CD  . ARG D 4  163 ? -45.51204 -24.97519 53.78175  1.000 51.48388 ? 177 ARG D CD  1 
ATOM   4266 N NE  . ARG D 4  163 ? -44.35562 -25.68499 53.24815  1.000 62.33586 ? 177 ARG D NE  1 
ATOM   4267 C CZ  . ARG D 4  163 ? -44.02095 -25.71301 51.96550  1.000 55.13184 ? 177 ARG D CZ  1 
ATOM   4268 N NH1 . ARG D 4  163 ? -44.73338 -25.07473 51.05160  1.000 55.10568 ? 177 ARG D NH1 1 
ATOM   4269 N NH2 . ARG D 4  163 ? -42.94419 -26.39813 51.59042  1.000 59.03784 ? 177 ARG D NH2 1 
ATOM   4270 N N   . SER D 4  164 ? -50.33974 -25.52836 56.40660  1.000 48.04088 ? 178 SER D N   1 
ATOM   4271 C CA  . SER D 4  164 ? -51.64480 -24.94347 56.70075  1.000 48.46665 ? 178 SER D CA  1 
ATOM   4272 C C   . SER D 4  164 ? -52.14451 -25.34128 58.08386  1.000 52.56649 ? 178 SER D C   1 
ATOM   4273 O O   . SER D 4  164 ? -52.87899 -24.57611 58.71920  1.000 57.29215 ? 178 SER D O   1 
ATOM   4274 C CB  . SER D 4  164 ? -52.66073 -25.35215 55.63448  1.000 45.44700 ? 178 SER D CB  1 
ATOM   4275 O OG  . SER D 4  164 ? -52.86561 -26.75393 55.63486  1.000 52.04686 ? 178 SER D OG  1 
ATOM   4276 N N   . MET D 4  165 ? -51.76538 -26.52329 58.56345  1.000 48.52019 ? 179 MET D N   1 
ATOM   4277 C CA  . MET D 4  165 ? -52.14450 -26.98604 59.89014  1.000 43.16510 ? 179 MET D CA  1 
ATOM   4278 C C   . MET D 4  165 ? -51.02364 -26.83860 60.90883  1.000 41.89024 ? 179 MET D C   1 
ATOM   4279 O O   . MET D 4  165 ? -51.23052 -27.15788 62.08384  1.000 46.21089 ? 179 MET D O   1 
ATOM   4280 C CB  . MET D 4  165 ? -52.59851 -28.44858 59.82963  1.000 44.31705 ? 179 MET D CB  1 
ATOM   4281 C CG  . MET D 4  165 ? -53.86045 -28.67206 59.01048  1.000 51.24449 ? 179 MET D CG  1 
ATOM   4282 S SD  . MET D 4  165 ? -54.41039 -30.38951 59.02747  1.000 71.81288 ? 179 MET D SD  1 
ATOM   4283 C CE  . MET D 4  165 ? -56.04048 -30.21899 59.75351  1.000 64.06953 ? 179 MET D CE  1 
ATOM   4284 N N   . ASP D 4  166 ? -49.85264 -26.35771 60.48819  1.000 47.34061 ? 180 ASP D N   1 
ATOM   4285 C CA  . ASP D 4  166 ? -48.68360 -26.21816 61.35771  1.000 46.69480 ? 180 ASP D CA  1 
ATOM   4286 C C   . ASP D 4  166 ? -48.38983 -27.52752 62.08774  1.000 43.26936 ? 180 ASP D C   1 
ATOM   4287 O O   . ASP D 4  166 ? -48.30380 -27.58439 63.31608  1.000 43.13497 ? 180 ASP D O   1 
ATOM   4288 C CB  . ASP D 4  166 ? -48.86606 -25.06253 62.34391  1.000 53.88446 ? 180 ASP D CB  1 
ATOM   4289 C CG  . ASP D 4  166 ? -47.56483 -24.65211 63.00739  1.000 64.05216 ? 180 ASP D CG  1 
ATOM   4290 O OD1 . ASP D 4  166 ? -46.55824 -24.48118 62.28737  1.000 71.19975 ? 180 ASP D OD1 1 
ATOM   4291 O OD2 . ASP D 4  166 ? -47.54812 -24.49849 64.24702  1.000 70.02157 ? 180 ASP D OD2 1 
ATOM   4292 N N   . PHE D 4  167 ? -48.24189 -28.59563 61.30818  1.000 41.28415 ? 181 PHE D N   1 
ATOM   4293 C CA  . PHE D 4  167 ? -48.04225 -29.93763 61.83623  1.000 36.32810 ? 181 PHE D CA  1 
ATOM   4294 C C   . PHE D 4  167 ? -46.88697 -30.59473 61.09769  1.000 36.00921 ? 181 PHE D C   1 
ATOM   4295 O O   . PHE D 4  167 ? -46.87022 -30.62187 59.86279  1.000 32.59099 ? 181 PHE D O   1 
ATOM   4296 C CB  . PHE D 4  167 ? -49.31925 -30.77797 61.69532  1.000 30.90912 ? 181 PHE D CB  1 
ATOM   4297 C CG  . PHE D 4  167 ? -49.17841 -32.19448 62.18346  1.000 34.14597 ? 181 PHE D CG  1 
ATOM   4298 C CD1 . PHE D 4  167 ? -49.44045 -32.51494 63.50566  1.000 35.55806 ? 181 PHE D CD1 1 
ATOM   4299 C CD2 . PHE D 4  167 ? -48.79724 -33.20810 61.31689  1.000 35.76717 ? 181 PHE D CD2 1 
ATOM   4300 C CE1 . PHE D 4  167 ? -49.31680 -33.81703 63.95723  1.000 30.84968 ? 181 PHE D CE1 1 
ATOM   4301 C CE2 . PHE D 4  167 ? -48.67188 -34.51144 61.76246  1.000 31.28936 ? 181 PHE D CE2 1 
ATOM   4302 C CZ  . PHE D 4  167 ? -48.93243 -34.81566 63.08426  1.000 33.43386 ? 181 PHE D CZ  1 
ATOM   4303 N N   . LYS D 4  168 ? -45.93044 -31.12415 61.85470  1.000 28.73980 ? 182 LYS D N   1 
ATOM   4304 C CA  . LYS D 4  168 ? -44.78408 -31.83153 61.30834  1.000 31.75496 ? 182 LYS D CA  1 
ATOM   4305 C C   . LYS D 4  168 ? -44.80466 -33.27550 61.78897  1.000 31.56179 ? 182 LYS D C   1 
ATOM   4306 O O   . LYS D 4  168 ? -45.29483 -33.57318 62.88279  1.000 29.42599 ? 182 LYS D O   1 
ATOM   4307 C CB  . LYS D 4  168 ? -43.46962 -31.16059 61.72354  1.000 26.36163 ? 182 LYS D CB  1 
ATOM   4308 C CG  . LYS D 4  168 ? -43.21834 -29.82263 61.04912  1.000 32.76318 ? 182 LYS D CG  1 
ATOM   4309 C CD  . LYS D 4  168 ? -42.26976 -28.96481 61.86985  1.000 39.62102 ? 182 LYS D CD  1 
ATOM   4310 C CE  . LYS D 4  168 ? -42.36056 -27.49986 61.47389  1.000 40.37308 ? 182 LYS D CE  1 
ATOM   4311 N NZ  . LYS D 4  168 ? -42.47779 -26.61119 62.66200  1.000 52.13072 ? 182 LYS D NZ  1 
ATOM   4312 N N   . SER D 4  169 ? -44.27053 -34.17550 60.96501  1.000 25.73455 ? 183 SER D N   1 
ATOM   4313 C CA  . SER D 4  169 ? -44.24852 -35.58453 61.32991  1.000 23.42166 ? 183 SER D CA  1 
ATOM   4314 C C   . SER D 4  169 ? -43.12009 -36.29250 60.59585  1.000 25.09595 ? 183 SER D C   1 
ATOM   4315 O O   . SER D 4  169 ? -42.81665 -35.96747 59.44502  1.000 22.82497 ? 183 SER D O   1 
ATOM   4316 C CB  . SER D 4  169 ? -45.58766 -36.26367 61.01776  1.000 24.60967 ? 183 SER D CB  1 
ATOM   4317 O OG  . SER D 4  169 ? -45.96811 -36.06074 59.66815  1.000 25.60438 ? 183 SER D OG  1 
ATOM   4318 N N   . ASN D 4  170 ? -42.50708 -37.25599 61.27493  1.000 24.13556 ? 184 ASN D N   1 
ATOM   4319 C CA  . ASN D 4  170 ? -41.53340 -38.14922 60.67069  1.000 23.91192 ? 184 ASN D CA  1 
ATOM   4320 C C   . ASN D 4  170 ? -42.23255 -39.38390 60.11348  1.000 22.84934 ? 184 ASN D C   1 
ATOM   4321 O O   . ASN D 4  170 ? -43.33583 -39.74466 60.53126  1.000 22.84761 ? 184 ASN D O   1 
ATOM   4322 C CB  . ASN D 4  170 ? -40.47686 -38.57099 61.69201  1.000 25.34821 ? 184 ASN D CB  1 
ATOM   4323 C CG  . ASN D 4  170 ? -39.77434 -37.39083 62.32601  1.000 31.62412 ? 184 ASN D CG  1 
ATOM   4324 O OD1 . ASN D 4  170 ? -39.28179 -36.50139 61.63246  1.000 32.08920 ? 184 ASN D OD1 1 
ATOM   4325 N ND2 . ASN D 4  170 ? -39.72617 -37.37483 63.65328  1.000 22.44043 ? 184 ASN D ND2 1 
ATOM   4326 N N   . SER D 4  171 ? -41.57055 -40.03799 59.16239  1.000 23.72714 ? 185 SER D N   1 
ATOM   4327 C CA  . SER D 4  171 ? -42.10628 -41.26713 58.59742  1.000 23.69936 ? 185 SER D CA  1 
ATOM   4328 C C   . SER D 4  171 ? -40.99111 -42.03045 57.89930  1.000 25.88186 ? 185 SER D C   1 
ATOM   4329 O O   . SER D 4  171 ? -39.98038 -41.45660 57.48695  1.000 25.80014 ? 185 SER D O   1 
ATOM   4330 C CB  . SER D 4  171 ? -43.25933 -40.99066 57.62340  1.000 25.67053 ? 185 SER D CB  1 
ATOM   4331 O OG  . SER D 4  171 ? -42.79996 -40.34233 56.44985  1.000 27.34379 ? 185 SER D OG  1 
ATOM   4332 N N   . ALA D 4  172 ? -41.19252 -43.34221 57.78636  1.000 25.96476 ? 186 ALA D N   1 
ATOM   4333 C CA  . ALA D 4  172 ? -40.33334 -44.22160 57.00827  1.000 22.34165 ? 186 ALA D CA  1 
ATOM   4334 C C   . ALA D 4  172 ? -41.20944 -45.26342 56.32901  1.000 23.51733 ? 186 ALA D C   1 
ATOM   4335 O O   . ALA D 4  172 ? -42.22525 -45.69209 56.88097  1.000 20.06563 ? 186 ALA D O   1 
ATOM   4336 C CB  . ALA D 4  172 ? -39.26700 -44.90142 57.87748  1.000 24.32129 ? 186 ALA D CB  1 
ATOM   4337 N N   . VAL D 4  173 ? -40.81612 -45.66480 55.12327  1.000 24.78335 ? 187 VAL D N   1 
ATOM   4338 C CA  . VAL D 4  173 ? -41.62591 -46.54249 54.28658  1.000 22.73220 ? 187 VAL D CA  1 
ATOM   4339 C C   . VAL D 4  173 ? -40.89893 -47.86785 54.10464  1.000 23.06348 ? 187 VAL D C   1 
ATOM   4340 O O   . VAL D 4  173 ? -39.69063 -47.89006 53.84438  1.000 27.57034 ? 187 VAL D O   1 
ATOM   4341 C CB  . VAL D 4  173 ? -41.93858 -45.89080 52.92665  1.000 28.44250 ? 187 VAL D CB  1 
ATOM   4342 C CG1 . VAL D 4  173 ? -42.57748 -46.89509 51.98186  1.000 33.79426 ? 187 VAL D CG1 1 
ATOM   4343 C CG2 . VAL D 4  173 ? -42.85485 -44.69232 53.12016  1.000 28.73196 ? 187 VAL D CG2 1 
ATOM   4344 N N   . ALA D 4  174 ? -41.63575 -48.96674 54.25394  1.000 22.78061 ? 188 ALA D N   1 
ATOM   4345 C CA  . ALA D 4  174 ? -41.14908 -50.30764 53.96463  1.000 27.56861 ? 188 ALA D CA  1 
ATOM   4346 C C   . ALA D 4  174 ? -42.06753 -50.95925 52.93990  1.000 30.86079 ? 188 ALA D C   1 
ATOM   4347 O O   . ALA D 4  174 ? -43.28919 -50.78546 52.99435  1.000 27.03178 ? 188 ALA D O   1 
ATOM   4348 C CB  . ALA D 4  174 ? -41.08559 -51.16473 55.23312  1.000 23.21086 ? 188 ALA D CB  1 
ATOM   4349 N N   . TRP D 4  175 ? -41.48419 -51.70588 52.00251  1.000 26.56673 ? 189 TRP D N   1 
ATOM   4350 C CA  . TRP D 4  175 ? -42.28711 -52.35915 50.97867  1.000 31.46501 ? 189 TRP D CA  1 
ATOM   4351 C C   . TRP D 4  175 ? -41.59352 -53.62193 50.48883  1.000 29.98674 ? 189 TRP D C   1 
ATOM   4352 O O   . TRP D 4  175 ? -40.38349 -53.80087 50.65306  1.000 26.74924 ? 189 TRP D O   1 
ATOM   4353 C CB  . TRP D 4  175 ? -42.58576 -51.41413 49.80505  1.000 24.34084 ? 189 TRP D CB  1 
ATOM   4354 C CG  . TRP D 4  175 ? -41.44636 -51.20212 48.85270  1.000 31.39171 ? 189 TRP D CG  1 
ATOM   4355 C CD1 . TRP D 4  175 ? -41.08907 -52.00304 47.80386  1.000 36.83881 ? 189 TRP D CD1 1 
ATOM   4356 C CD2 . TRP D 4  175 ? -40.53246 -50.10004 48.84315  1.000 31.37501 ? 189 TRP D CD2 1 
ATOM   4357 N NE1 . TRP D 4  175 ? -40.00170 -51.47378 47.15307  1.000 29.94305 ? 189 TRP D NE1 1 
ATOM   4358 C CE2 . TRP D 4  175 ? -39.64170 -50.30482 47.77015  1.000 28.03019 ? 189 TRP D CE2 1 
ATOM   4359 C CE3 . TRP D 4  175 ? -40.37668 -48.96278 49.64138  1.000 32.64334 ? 189 TRP D CE3 1 
ATOM   4360 C CZ2 . TRP D 4  175 ? -38.61138 -49.41619 47.47645  1.000 31.58918 ? 189 TRP D CZ2 1 
ATOM   4361 C CZ3 . TRP D 4  175 ? -39.35194 -48.08094 49.34648  1.000 29.90079 ? 189 TRP D CZ3 1 
ATOM   4362 C CH2 . TRP D 4  175 ? -38.48332 -48.31300 48.27426  1.000 31.88016 ? 189 TRP D CH2 1 
ATOM   4363 N N   . SER D 4  176 ? -42.38983 -54.49336 49.87380  1.000 33.71122 ? 190 SER D N   1 
ATOM   4364 C CA  . SER D 4  176 ? -41.93911 -55.77934 49.35853  1.000 33.10403 ? 190 SER D CA  1 
ATOM   4365 C C   . SER D 4  176 ? -43.04075 -56.35788 48.48455  1.000 36.69731 ? 190 SER D C   1 
ATOM   4366 O O   . SER D 4  176 ? -44.21947 -56.03084 48.64839  1.000 32.53912 ? 190 SER D O   1 
ATOM   4367 C CB  . SER D 4  176 ? -41.59417 -56.75265 50.49240  1.000 34.32930 ? 190 SER D CB  1 
ATOM   4368 O OG  . SER D 4  176 ? -41.16216 -58.00153 49.97989  1.000 35.94380 ? 190 SER D OG  1 
ATOM   4369 N N   . ASN D 4  177 ? -42.64391 -57.22324 47.55347  1.000 32.32278 ? 191 ASN D N   1 
ATOM   4370 C CA  . ASN D 4  177 ? -43.59716 -57.98365 46.75872  1.000 36.16136 ? 191 ASN D CA  1 
ATOM   4371 C C   . ASN D 4  177 ? -43.69970 -59.43522 47.20945  1.000 37.47050 ? 191 ASN D C   1 
ATOM   4372 O O   . ASN D 4  177 ? -44.35199 -60.23920 46.53646  1.000 46.62815 ? 191 ASN D O   1 
ATOM   4373 C CB  . ASN D 4  177 ? -43.24025 -57.91078 45.26951  1.000 32.86504 ? 191 ASN D CB  1 
ATOM   4374 C CG  . ASN D 4  177 ? -41.86405 -58.47750 44.95742  1.000 39.33601 ? 191 ASN D CG  1 
ATOM   4375 O OD1 . ASN D 4  177 ? -41.24334 -59.14751 45.78273  1.000 38.21759 ? 191 ASN D OD1 1 
ATOM   4376 N ND2 . ASN D 4  177 ? -41.38643 -58.21566 43.74681  1.000 42.24095 ? 191 ASN D ND2 1 
ATOM   4377 N N   . LYS D 4  178 ? -43.06767 -59.78678 48.32618  1.000 36.02078 ? 192 LYS D N   1 
ATOM   4378 C CA  . LYS D 4  178 ? -43.15489 -61.14568 48.83961  1.000 40.87914 ? 192 LYS D CA  1 
ATOM   4379 C C   . LYS D 4  178 ? -44.55424 -61.41789 49.37645  1.000 46.08999 ? 192 LYS D C   1 
ATOM   4380 O O   . LYS D 4  178 ? -45.19679 -60.53900 49.95784  1.000 41.37484 ? 192 LYS D O   1 
ATOM   4381 C CB  . LYS D 4  178 ? -42.11361 -61.36895 49.93617  1.000 40.73318 ? 192 LYS D CB  1 
ATOM   4382 N N   . SER D 4  179 ? -45.02731 -62.64978 49.17369  1.000 45.22228 ? 193 SER D N   1 
ATOM   4383 C CA  . SER D 4  179 ? -46.37669 -63.01150 49.59088  1.000 53.19167 ? 193 SER D CA  1 
ATOM   4384 C C   . SER D 4  179 ? -46.53192 -63.04503 51.10548  1.000 55.50458 ? 193 SER D C   1 
ATOM   4385 O O   . SER D 4  179 ? -47.65331 -62.89698 51.60267  1.000 60.11074 ? 193 SER D O   1 
ATOM   4386 C CB  . SER D 4  179 ? -46.76255 -64.36801 48.99921  1.000 58.59434 ? 193 SER D CB  1 
ATOM   4387 O OG  . SER D 4  179 ? -47.10367 -64.24753 47.62892  1.000 56.89358 ? 193 SER D OG  1 
ATOM   4388 N N   . ASP D 4  180 ? -45.44141 -63.23293 51.84640  1.000 53.59598 ? 194 ASP D N   1 
ATOM   4389 C CA  . ASP D 4  180 ? -45.48124 -63.29232 53.30057  1.000 58.31643 ? 194 ASP D CA  1 
ATOM   4390 C C   . ASP D 4  180 ? -45.16096 -61.95346 53.95432  1.000 59.35013 ? 194 ASP D C   1 
ATOM   4391 O O   . ASP D 4  180 ? -44.90476 -61.91172 55.16180  1.000 60.26849 ? 194 ASP D O   1 
ATOM   4392 C CB  . ASP D 4  180 ? -44.51512 -64.36497 53.80909  1.000 52.28353 ? 194 ASP D CB  1 
ATOM   4393 N N   . PHE D 4  181 ? -45.17225 -60.86325 53.19131  1.000 56.13530 ? 195 PHE D N   1 
ATOM   4394 C CA  . PHE D 4  181 ? -44.82819 -59.56094 53.74497  1.000 49.70385 ? 195 PHE D CA  1 
ATOM   4395 C C   . PHE D 4  181 ? -45.94867 -59.03842 54.63469  1.000 46.28485 ? 195 PHE D C   1 
ATOM   4396 O O   . PHE D 4  181 ? -47.13102 -59.12774 54.29209  1.000 45.42873 ? 195 PHE D O   1 
ATOM   4397 C CB  . PHE D 4  181 ? -44.54645 -58.56295 52.62363  1.000 41.93143 ? 195 PHE D CB  1 
ATOM   4398 C CG  . PHE D 4  181 ? -44.04627 -57.23266 53.10925  1.000 34.16434 ? 195 PHE D CG  1 
ATOM   4399 C CD1 . PHE D 4  181 ? -42.87512 -57.14435 53.84405  1.000 31.84428 ? 195 PHE D CD1 1 
ATOM   4400 C CD2 . PHE D 4  181 ? -44.74755 -56.07076 52.83211  1.000 30.49073 ? 195 PHE D CD2 1 
ATOM   4401 C CE1 . PHE D 4  181 ? -42.41089 -55.92157 54.29091  1.000 32.72888 ? 195 PHE D CE1 1 
ATOM   4402 C CE2 . PHE D 4  181 ? -44.28973 -54.84481 53.27744  1.000 31.78329 ? 195 PHE D CE2 1 
ATOM   4403 C CZ  . PHE D 4  181 ? -43.11921 -54.77031 54.00722  1.000 30.31961 ? 195 PHE D CZ  1 
ATOM   4404 N N   . ALA D 4  182 ? -45.56870 -58.48248 55.78296  1.000 37.16494 ? 196 ALA D N   1 
ATOM   4405 C CA  . ALA D 4  182 ? -46.53731 -57.93448 56.71916  1.000 38.59040 ? 196 ALA D CA  1 
ATOM   4406 C C   . ALA D 4  182 ? -45.87253 -56.85718 57.56151  1.000 35.24428 ? 196 ALA D C   1 
ATOM   4407 O O   . ALA D 4  182 ? -44.67436 -56.92151 57.84942  1.000 37.17180 ? 196 ALA D O   1 
ATOM   4408 C CB  . ALA D 4  182 ? -47.12860 -59.02174 57.61802  1.000 41.26367 ? 196 ALA D CB  1 
ATOM   4409 N N   . CYS D 4  183 ? -46.67216 -55.86741 57.96217  1.000 37.32324 ? 197 CYS D N   1 
ATOM   4410 C CA  . CYS D 4  183 ? -46.14085 -54.72388 58.69249  1.000 36.66983 ? 197 CYS D CA  1 
ATOM   4411 C C   . CYS D 4  183 ? -45.72196 -55.07592 60.11221  1.000 40.77026 ? 197 CYS D C   1 
ATOM   4412 O O   . CYS D 4  183 ? -44.90313 -54.35659 60.69499  1.000 42.79534 ? 197 CYS D O   1 
ATOM   4413 C CB  . CYS D 4  183 ? -47.17586 -53.60087 58.72396  1.000 33.70269 ? 197 CYS D CB  1 
ATOM   4414 S SG  . CYS D 4  183 ? -47.72523 -53.07212 57.09052  1.000 48.63163 ? 197 CYS D SG  1 
ATOM   4415 N N   . ALA D 4  184 ? -46.25496 -56.16464 60.67498  1.000 36.83294 ? 198 ALA D N   1 
ATOM   4416 C CA  . ALA D 4  184 ? -45.96495 -56.50388 62.06518  1.000 37.51909 ? 198 ALA D CA  1 
ATOM   4417 C C   . ALA D 4  184 ? -44.47589 -56.72062 62.30357  1.000 42.85683 ? 198 ALA D C   1 
ATOM   4418 O O   . ALA D 4  184 ? -43.98527 -56.47666 63.41219  1.000 40.79770 ? 198 ALA D O   1 
ATOM   4419 C CB  . ALA D 4  184 ? -46.75302 -57.74723 62.47669  1.000 41.30688 ? 198 ALA D CB  1 
ATOM   4420 N N   . ASN D 4  185 ? -43.73885 -57.16804 61.28353  1.000 36.80294 ? 199 ASN D N   1 
ATOM   4421 C CA  . ASN D 4  185 ? -42.31404 -57.43611 61.42934  1.000 37.68207 ? 199 ASN D CA  1 
ATOM   4422 C C   . ASN D 4  185 ? -41.46476 -56.70519 60.39740  1.000 33.77134 ? 199 ASN D C   1 
ATOM   4423 O O   . ASN D 4  185 ? -40.27226 -57.00834 60.27284  1.000 34.87514 ? 199 ASN D O   1 
ATOM   4424 C CB  . ASN D 4  185 ? -42.04072 -58.94149 61.34454  1.000 44.59544 ? 199 ASN D CB  1 
ATOM   4425 C CG  . ASN D 4  185 ? -42.84682 -59.73525 62.34935  1.000 56.12537 ? 199 ASN D CG  1 
ATOM   4426 O OD1 . ASN D 4  185 ? -43.76050 -60.47343 61.98225  1.000 61.94782 ? 199 ASN D OD1 1 
ATOM   4427 N ND2 . ASN D 4  185 ? -42.51509 -59.58570 63.62736  1.000 56.91866 ? 199 ASN D ND2 1 
ATOM   4428 N N   . ALA D 4  186 ? -42.04047 -55.75140 59.66135  1.000 31.88892 ? 200 ALA D N   1 
ATOM   4429 C CA  . ALA D 4  186 ? -41.29389 -55.07840 58.60238  1.000 37.19047 ? 200 ALA D CA  1 
ATOM   4430 C C   . ALA D 4  186 ? -40.09883 -54.31449 59.16000  1.000 36.26155 ? 200 ALA D C   1 
ATOM   4431 O O   . ALA D 4  186 ? -39.02428 -54.29673 58.54865  1.000 32.38884 ? 200 ALA D O   1 
ATOM   4432 C CB  . ALA D 4  186 ? -42.21756 -54.13945 57.82713  1.000 28.86202 ? 200 ALA D CB  1 
ATOM   4433 N N   . PHE D 4  187 ? -40.26312 -53.68355 60.32077  1.000 31.39628 ? 201 PHE D N   1 
ATOM   4434 C CA  . PHE D 4  187 ? -39.20591 -52.89733 60.95404  1.000 37.29606 ? 201 PHE D CA  1 
ATOM   4435 C C   . PHE D 4  187 ? -38.56714 -53.63806 62.12139  1.000 39.04590 ? 201 PHE D C   1 
ATOM   4436 O O   . PHE D 4  187 ? -38.18928 -53.02490 63.12323  1.000 39.76274 ? 201 PHE D O   1 
ATOM   4437 C CB  . PHE D 4  187 ? -39.75530 -51.54993 61.41139  1.000 31.73437 ? 201 PHE D CB  1 
ATOM   4438 C CG  . PHE D 4  187 ? -40.31903 -50.71734 60.29710  1.000 29.11561 ? 201 PHE D CG  1 
ATOM   4439 C CD1 . PHE D 4  187 ? -39.51301 -49.83285 59.60140  1.000 27.09393 ? 201 PHE D CD1 1 
ATOM   4440 C CD2 . PHE D 4  187 ? -41.65514 -50.81923 59.94519  1.000 27.97751 ? 201 PHE D CD2 1 
ATOM   4441 C CE1 . PHE D 4  187 ? -40.02759 -49.06596 58.57443  1.000 29.43071 ? 201 PHE D CE1 1 
ATOM   4442 C CE2 . PHE D 4  187 ? -42.17655 -50.05522 58.91979  1.000 27.16930 ? 201 PHE D CE2 1 
ATOM   4443 C CZ  . PHE D 4  187 ? -41.36082 -49.17732 58.23251  1.000 30.10879 ? 201 PHE D CZ  1 
ATOM   4444 N N   . ASN D 4  188 ? -38.42682 -54.96177 62.01156  1.000 37.29482 ? 202 ASN D N   1 
ATOM   4445 C CA  . ASN D 4  188 ? -37.89020 -55.74512 63.11970  1.000 40.18256 ? 202 ASN D CA  1 
ATOM   4446 C C   . ASN D 4  188 ? -36.42418 -55.42960 63.38791  1.000 44.85120 ? 202 ASN D C   1 
ATOM   4447 O O   . ASN D 4  188 ? -35.96322 -55.56709 64.52627  1.000 45.26708 ? 202 ASN D O   1 
ATOM   4448 C CB  . ASN D 4  188 ? -38.06574 -57.23703 62.84251  1.000 42.17873 ? 202 ASN D CB  1 
ATOM   4449 C CG  . ASN D 4  188 ? -39.17558 -57.85427 63.66793  1.000 58.69039 ? 202 ASN D CG  1 
ATOM   4450 O OD1 . ASN D 4  188 ? -40.19273 -57.21554 63.94232  1.000 52.43939 ? 202 ASN D OD1 1 
ATOM   4451 N ND2 . ASN D 4  188 ? -38.98213 -59.10160 64.07619  1.000 66.86683 ? 202 ASN D ND2 1 
ATOM   4452 N N   . ASN D 4  189 ? -35.67803 -55.01201 62.36797  1.000 39.39088 ? 203 ASN D N   1 
ATOM   4453 C CA  . ASN D 4  189 ? -34.27684 -54.66071 62.55682  1.000 42.35853 ? 203 ASN D CA  1 
ATOM   4454 C C   . ASN D 4  189 ? -34.08815 -53.26987 63.14781  1.000 39.43917 ? 203 ASN D C   1 
ATOM   4455 O O   . ASN D 4  189 ? -32.94341 -52.84479 63.33599  1.000 36.52089 ? 203 ASN D O   1 
ATOM   4456 C CB  . ASN D 4  189 ? -33.52231 -54.76392 61.22891  1.000 42.05616 ? 203 ASN D CB  1 
ATOM   4457 C CG  . ASN D 4  189 ? -32.03101 -54.95356 61.42249  1.000 51.89624 ? 203 ASN D CG  1 
ATOM   4458 O OD1 . ASN D 4  189 ? -31.59844 -55.80126 62.20444  1.000 49.03031 ? 203 ASN D OD1 1 
ATOM   4459 N ND2 . ASN D 4  189 ? -31.23580 -54.16010 60.71328  1.000 46.57580 ? 203 ASN D ND2 1 
ATOM   4460 N N   . SER D 4  190 ? -35.16941 -52.55581 63.44312  1.000 35.48408 ? 204 SER D N   1 
ATOM   4461 C CA  . SER D 4  190 ? -35.10059 -51.22705 64.03023  1.000 33.59311 ? 204 SER D CA  1 
ATOM   4462 C C   . SER D 4  190 ? -35.57336 -51.27536 65.47597  1.000 42.90806 ? 204 SER D C   1 
ATOM   4463 O O   . SER D 4  190 ? -36.48179 -52.03968 65.81788  1.000 39.99068 ? 204 SER D O   1 
ATOM   4464 C CB  . SER D 4  190 ? -35.95338 -50.22906 63.24132  1.000 32.09652 ? 204 SER D CB  1 
ATOM   4465 O OG  . SER D 4  190 ? -35.43098 -50.01671 61.94226  1.000 38.13084 ? 204 SER D OG  1 
ATOM   4466 N N   . ILE D 4  191 ? -34.94781 -50.46120 66.32374  1.000 34.27435 ? 205 ILE D N   1 
ATOM   4467 C CA  . ILE D 4  191 ? -35.40727 -50.27823 67.69778  1.000 37.04072 ? 205 ILE D CA  1 
ATOM   4468 C C   . ILE D 4  191 ? -36.51692 -49.23168 67.65517  1.000 33.27053 ? 205 ILE D C   1 
ATOM   4469 O O   . ILE D 4  191 ? -36.25388 -48.03298 67.54859  1.000 32.97275 ? 205 ILE D O   1 
ATOM   4470 C CB  . ILE D 4  191 ? -34.27156 -49.86604 68.63674  1.000 38.53719 ? 205 ILE D CB  1 
ATOM   4471 C CG1 . ILE D 4  191 ? -33.03449 -50.73131 68.39135  1.000 35.65617 ? 205 ILE D CG1 1 
ATOM   4472 C CG2 . ILE D 4  191 ? -34.71784 -49.97124 70.08828  1.000 41.39338 ? 205 ILE D CG2 1 
ATOM   4473 C CD1 . ILE D 4  191 ? -31.79823 -50.24427 69.11570  1.000 45.13474 ? 205 ILE D CD1 1 
ATOM   4474 N N   . ILE D 4  192 ? -37.76378 -49.68523 67.72135  1.000 30.39312 ? 206 ILE D N   1 
ATOM   4475 C CA  . ILE D 4  192 ? -38.91843 -48.79459 67.64918  1.000 30.52682 ? 206 ILE D CA  1 
ATOM   4476 C C   . ILE D 4  192 ? -39.59063 -48.75750 69.01684  1.000 29.67860 ? 206 ILE D C   1 
ATOM   4477 O O   . ILE D 4  192 ? -39.43811 -49.70346 69.80407  1.000 25.90744 ? 206 ILE D O   1 
ATOM   4478 C CB  . ILE D 4  192 ? -39.89178 -49.23596 66.54325  1.000 31.68843 ? 206 ILE D CB  1 
ATOM   4479 C CG1 . ILE D 4  192 ? -40.75526 -50.40685 67.01357  1.000 25.64904 ? 206 ILE D CG1 1 
ATOM   4480 C CG2 . ILE D 4  192 ? -39.13047 -49.60317 65.27375  1.000 33.04911 ? 206 ILE D CG2 1 
ATOM   4481 C CD1 . ILE D 4  192 ? -41.87102 -50.75446 66.05233  1.000 37.08020 ? 206 ILE D CD1 1 
ATOM   4482 N N   . PRO D 4  193 ? -40.31151 -47.68698 69.35228  1.000 23.97645 ? 207 PRO D N   1 
ATOM   4483 C CA  . PRO D 4  193 ? -40.93549 -47.60682 70.67877  1.000 29.27658 ? 207 PRO D CA  1 
ATOM   4484 C C   . PRO D 4  193 ? -41.87573 -48.77683 70.93159  1.000 29.35409 ? 207 PRO D C   1 
ATOM   4485 O O   . PRO D 4  193 ? -42.59352 -49.22996 70.03715  1.000 29.70995 ? 207 PRO D O   1 
ATOM   4486 C CB  . PRO D 4  193 ? -41.69180 -46.27137 70.64384  1.000 26.70614 ? 207 PRO D CB  1 
ATOM   4487 C CG  . PRO D 4  193 ? -41.55165 -45.73668 69.24876  1.000 27.42462 ? 207 PRO D CG  1 
ATOM   4488 C CD  . PRO D 4  193 ? -40.39502 -46.41494 68.61709  1.000 21.51931 ? 207 PRO D CD  1 
ATOM   4489 N N   . GLU D 4  194 ? -41.85863 -49.26761 72.17358  1.000 24.72056 ? 208 GLU D N   1 
ATOM   4490 C CA  . GLU D 4  194 ? -42.66464 -50.42664 72.53850  1.000 30.63610 ? 208 GLU D CA  1 
ATOM   4491 C C   . GLU D 4  194 ? -44.15768 -50.12721 72.52761  1.000 27.93637 ? 208 GLU D C   1 
ATOM   4492 O O   . GLU D 4  194 ? -44.96263 -51.06369 72.49800  1.000 28.90943 ? 208 GLU D O   1 
ATOM   4493 C CB  . GLU D 4  194 ? -42.24726 -50.94324 73.91677  1.000 31.27601 ? 208 GLU D CB  1 
ATOM   4494 C CG  . GLU D 4  194 ? -40.98520 -51.79173 73.90379  1.000 36.13815 ? 208 GLU D CG  1 
ATOM   4495 C CD  . GLU D 4  194 ? -41.17546 -53.11858 73.19477  1.000 40.00890 ? 208 GLU D CD  1 
ATOM   4496 O OE1 . GLU D 4  194 ? -42.31302 -53.63512 73.18578  1.000 51.39549 ? 208 GLU D OE1 1 
ATOM   4497 O OE2 . GLU D 4  194 ? -40.18453 -53.64703 72.64829  1.000 52.82294 ? 208 GLU D OE2 1 
ATOM   4498 N N   . ASP D 4  195 ? -44.54596 -48.85286 72.55182  1.000 20.55350 ? 209 ASP D N   1 
ATOM   4499 C CA  . ASP D 4  195 ? -45.94539 -48.46288 72.47246  1.000 26.03291 ? 209 ASP D CA  1 
ATOM   4500 C C   . ASP D 4  195 ? -46.39603 -48.17735 71.04326  1.000 29.34456 ? 209 ASP D C   1 
ATOM   4501 O O   . ASP D 4  195 ? -47.44669 -47.55416 70.85038  1.000 27.73723 ? 209 ASP D O   1 
ATOM   4502 C CB  . ASP D 4  195 ? -46.20572 -47.23960 73.35487  1.000 25.78529 ? 209 ASP D CB  1 
ATOM   4503 C CG  . ASP D 4  195 ? -45.29601 -46.07441 73.01729  1.000 42.89942 ? 209 ASP D CG  1 
ATOM   4504 O OD1 . ASP D 4  195 ? -44.10485 -46.31357 72.73033  1.000 39.09989 ? 209 ASP D OD1 1 
ATOM   4505 O OD2 . ASP D 4  195 ? -45.77294 -44.91999 73.03149  1.000 50.59926 ? 209 ASP D OD2 1 
ATOM   4506 N N   . THR D 4  196 ? -45.62958 -48.61473 70.04365  1.000 23.90887 ? 210 THR D N   1 
ATOM   4507 C CA  . THR D 4  196 ? -46.00136 -48.37190 68.65455  1.000 25.80506 ? 210 THR D CA  1 
ATOM   4508 C C   . THR D 4  196 ? -47.31376 -49.07333 68.32074  1.000 23.29525 ? 210 THR D C   1 
ATOM   4509 O O   . THR D 4  196 ? -47.48456 -50.26573 68.59115  1.000 21.94577 ? 210 THR D O   1 
ATOM   4510 C CB  . THR D 4  196 ? -44.89306 -48.84783 67.71174  1.000 23.28096 ? 210 THR D CB  1 
ATOM   4511 O OG1 . THR D 4  196 ? -43.69995 -48.08708 67.94464  1.000 22.92217 ? 210 THR D OG1 1 
ATOM   4512 C CG2 . THR D 4  196 ? -45.31621 -48.67173 66.25747  1.000 26.06830 ? 210 THR D CG2 1 
ATOM   4513 N N   . PHE D 4  197 ? -48.24033 -48.32068 67.73330  1.000 19.79477 ? 211 PHE D N   1 
ATOM   4514 C CA  . PHE D 4  197 ? -49.55321 -48.83488 67.36146  1.000 19.39055 ? 211 PHE D CA  1 
ATOM   4515 C C   . PHE D 4  197 ? -49.43819 -49.66932 66.08810  1.000 26.04124 ? 211 PHE D C   1 
ATOM   4516 O O   . PHE D 4  197 ? -48.95424 -49.18091 65.06176  1.000 25.46689 ? 211 PHE D O   1 
ATOM   4517 C CB  . PHE D 4  197 ? -50.51819 -47.66593 67.17095  1.000 22.16011 ? 211 PHE D CB  1 
ATOM   4518 C CG  . PHE D 4  197 ? -51.93363 -48.07392 66.88301  1.000 27.12552 ? 211 PHE D CG  1 
ATOM   4519 C CD1 . PHE D 4  197 ? -52.48181 -49.20302 67.46648  1.000 27.64182 ? 211 PHE D CD1 1 
ATOM   4520 C CD2 . PHE D 4  197 ? -52.72331 -47.31146 66.03727  1.000 25.11205 ? 211 PHE D CD2 1 
ATOM   4521 C CE1 . PHE D 4  197 ? -53.78932 -49.57011 67.20267  1.000 28.85328 ? 211 PHE D CE1 1 
ATOM   4522 C CE2 . PHE D 4  197 ? -54.03063 -47.67175 65.77171  1.000 28.26256 ? 211 PHE D CE2 1 
ATOM   4523 C CZ  . PHE D 4  197 ? -54.56400 -48.80290 66.35509  1.000 26.04864 ? 211 PHE D CZ  1 
ATOM   4524 N N   . PHE D 4  198 ? -49.88384 -50.92637 66.15037  1.000 26.36775 ? 212 PHE D N   1 
ATOM   4525 C CA  . PHE D 4  198 ? -49.81972 -51.85909 65.02502  1.000 25.41474 ? 212 PHE D CA  1 
ATOM   4526 C C   . PHE D 4  198 ? -51.22937 -52.31688 64.65634  1.000 25.73012 ? 212 PHE D C   1 
ATOM   4527 O O   . PHE D 4  198 ? -51.58392 -53.48718 64.85572  1.000 27.53427 ? 212 PHE D O   1 
ATOM   4528 C CB  . PHE D 4  198 ? -48.94269 -53.06481 65.35942  1.000 25.12776 ? 212 PHE D CB  1 
ATOM   4529 C CG  . PHE D 4  198 ? -47.47293 -52.84279 65.12046  1.000 29.03115 ? 212 PHE D CG  1 
ATOM   4530 C CD1 . PHE D 4  198 ? -46.91224 -53.09153 63.87724  1.000 32.48530 ? 212 PHE D CD1 1 
ATOM   4531 C CD2 . PHE D 4  198 ? -46.64907 -52.40510 66.14476  1.000 25.24118 ? 212 PHE D CD2 1 
ATOM   4532 C CE1 . PHE D 4  198 ? -45.55749 -52.89676 63.65690  1.000 30.38018 ? 212 PHE D CE1 1 
ATOM   4533 C CE2 . PHE D 4  198 ? -45.29455 -52.20754 65.93087  1.000 33.36910 ? 212 PHE D CE2 1 
ATOM   4534 C CZ  . PHE D 4  198 ? -44.74909 -52.45301 64.68564  1.000 30.69249 ? 212 PHE D CZ  1 
ATOM   4535 N N   . PRO D 4  199 ? -52.05521 -51.42686 64.10535  1.000 22.84143 ? 213 PRO D N   1 
ATOM   4536 C CA  . PRO D 4  199 ? -53.44245 -51.80599 63.81139  1.000 29.83067 ? 213 PRO D CA  1 
ATOM   4537 C C   . PRO D 4  199 ? -53.51305 -52.90637 62.76362  1.000 34.93897 ? 213 PRO D C   1 
ATOM   4538 O O   . PRO D 4  199 ? -52.67571 -52.99513 61.86221  1.000 26.07426 ? 213 PRO D O   1 
ATOM   4539 C CB  . PRO D 4  199 ? -54.06841 -50.50452 63.29728  1.000 29.07778 ? 213 PRO D CB  1 
ATOM   4540 C CG  . PRO D 4  199 ? -52.91953 -49.71229 62.78117  1.000 28.96962 ? 213 PRO D CG  1 
ATOM   4541 C CD  . PRO D 4  199 ? -51.75035 -50.05644 63.65881  1.000 22.52162 ? 213 PRO D CD  1 
ATOM   4542 N N   . SER D 4  200 ? -54.52565 -53.75567 62.90247  1.000 35.36134 ? 214 SER D N   1 
ATOM   4543 C CA  . SER D 4  200 ? -54.72234 -54.83753 61.95127  1.000 40.48849 ? 214 SER D CA  1 
ATOM   4544 C C   . SER D 4  200 ? -55.04356 -54.26149 60.57349  1.000 36.85718 ? 214 SER D C   1 
ATOM   4545 O O   . SER D 4  200 ? -55.78030 -53.27283 60.47051  1.000 34.98077 ? 214 SER D O   1 
ATOM   4546 C CB  . SER D 4  200 ? -55.85084 -55.75958 62.41774  1.000 36.22867 ? 214 SER D CB  1 
ATOM   4547 O OG  . SER D 4  200 ? -55.63528 -57.09242 61.98762  1.000 49.59908 ? 214 SER D OG  1 
ATOM   4548 N N   . PRO D 4  201 ? -54.50215 -54.84517 59.49200  1.000 33.60232 ? 215 PRO D N   1 
ATOM   4549 C CA  . PRO D 4  201 ? -54.69294 -54.35115 58.12147  1.000 37.98290 ? 215 PRO D CA  1 
ATOM   4550 C C   . PRO D 4  201 ? -56.15521 -54.34642 57.67960  1.000 38.12003 ? 215 PRO D C   1 
ATOM   4551 O O   . PRO D 4  201 ? -56.95248 -55.10803 58.22726  1.000 43.07605 ? 215 PRO D O   1 
ATOM   4552 C CB  . PRO D 4  201 ? -53.87778 -55.33741 57.27500  1.000 31.31870 ? 215 PRO D CB  1 
ATOM   4553 C CG  . PRO D 4  201 ? -52.89875 -55.94314 58.22399  1.000 41.57174 ? 215 PRO D CG  1 
ATOM   4554 C CD  . PRO D 4  201 ? -53.61478 -56.01935 59.53436  1.000 34.15967 ? 215 PRO D CD  1 
ATOM   4555 N N   . GLY E 5  2   ? -29.30565 -16.12418 34.94521  1.000 36.42338 ? 3   GLY E N   1 
ATOM   4556 C CA  . GLY E 5  2   ? -28.90603 -17.33453 35.64072  1.000 37.68782 ? 3   GLY E CA  1 
ATOM   4557 C C   . GLY E 5  2   ? -28.00158 -18.22048 34.80657  1.000 35.66725 ? 3   GLY E C   1 
ATOM   4558 O O   . GLY E 5  2   ? -27.89669 -18.04171 33.59280  1.000 37.30005 ? 3   GLY E O   1 
ATOM   4559 N N   . VAL E 5  3   ? -27.34618 -19.17751 35.45743  1.000 30.83453 ? 4   VAL E N   1 
ATOM   4560 C CA  . VAL E 5  3   ? -26.44087 -20.09003 34.76726  1.000 27.51281 ? 4   VAL E CA  1 
ATOM   4561 C C   . VAL E 5  3   ? -27.24824 -21.21708 34.13661  1.000 28.55982 ? 4   VAL E C   1 
ATOM   4562 O O   . VAL E 5  3   ? -28.05152 -21.87501 34.80871  1.000 26.93017 ? 4   VAL E O   1 
ATOM   4563 C CB  . VAL E 5  3   ? -25.38232 -20.64314 35.73331  1.000 27.46020 ? 4   VAL E CB  1 
ATOM   4564 C CG1 . VAL E 5  3   ? -24.42012 -21.53781 34.98539  1.000 22.20104 ? 4   VAL E CG1 1 
ATOM   4565 C CG2 . VAL E 5  3   ? -24.63580 -19.50953 36.41722  1.000 22.25332 ? 4   VAL E CG2 1 
ATOM   4566 N N   . THR E 5  4   ? -27.02750 -21.45077 32.84587  1.000 27.06792 ? 5   THR E N   1 
ATOM   4567 C CA  . THR E 5  4   ? -27.73291 -22.47877 32.09145  1.000 31.34022 ? 5   THR E CA  1 
ATOM   4568 C C   . THR E 5  4   ? -26.75666 -23.57387 31.68310  1.000 26.87274 ? 5   THR E C   1 
ATOM   4569 O O   . THR E 5  4   ? -25.70472 -23.28749 31.10261  1.000 29.74006 ? 5   THR E O   1 
ATOM   4570 C CB  . THR E 5  4   ? -28.40394 -21.88414 30.85011  1.000 32.61482 ? 5   THR E CB  1 
ATOM   4571 O OG1 . THR E 5  4   ? -29.24438 -20.78974 31.23723  1.000 36.19175 ? 5   THR E OG1 1 
ATOM   4572 C CG2 . THR E 5  4   ? -29.24240 -22.93706 30.13936  1.000 32.76448 ? 5   THR E CG2 1 
ATOM   4573 N N   . GLN E 5  5   ? -27.11104 -24.82230 31.97956  1.000 24.60609 ? 6   GLN E N   1 
ATOM   4574 C CA  . GLN E 5  5   ? -26.28491 -25.98041 31.66671  1.000 23.95483 ? 6   GLN E CA  1 
ATOM   4575 C C   . GLN E 5  5   ? -27.08856 -26.95786 30.82317  1.000 27.07968 ? 6   GLN E C   1 
ATOM   4576 O O   . GLN E 5  5   ? -28.22603 -27.29147 31.17051  1.000 27.09316 ? 6   GLN E O   1 
ATOM   4577 C CB  . GLN E 5  5   ? -25.79046 -26.66886 32.94428  1.000 20.90623 ? 6   GLN E CB  1 
ATOM   4578 C CG  . GLN E 5  5   ? -24.44724 -26.16679 33.43468  1.000 19.32969 ? 6   GLN E CG  1 
ATOM   4579 C CD  . GLN E 5  5   ? -23.83473 -27.05946 34.49971  1.000 23.44513 ? 6   GLN E CD  1 
ATOM   4580 O OE1 . GLN E 5  5   ? -23.96823 -26.80083 35.69759  1.000 21.72602 ? 6   GLN E OE1 1 
ATOM   4581 N NE2 . GLN E 5  5   ? -23.15512 -28.11531 34.06680  1.000 19.84641 ? 6   GLN E NE2 1 
ATOM   4582 N N   . THR E 5  6   ? -26.49537 -27.41597 29.71864  1.000 19.79550 ? 7   THR E N   1 
ATOM   4583 C CA  . THR E 5  6   ? -27.12684 -28.37726 28.82940  1.000 24.91560 ? 7   THR E CA  1 
ATOM   4584 C C   . THR E 5  6   ? -26.09580 -29.40747 28.38751  1.000 28.20134 ? 7   THR E C   1 
ATOM   4585 O O   . THR E 5  6   ? -24.92133 -29.06381 28.18506  1.000 25.64377 ? 7   THR E O   1 
ATOM   4586 C CB  . THR E 5  6   ? -27.73881 -27.70511 27.58967  1.000 29.23319 ? 7   THR E CB  1 
ATOM   4587 O OG1 . THR E 5  6   ? -26.77670 -26.82778 26.99184  1.000 30.79698 ? 7   THR E OG1 1 
ATOM   4588 C CG2 . THR E 5  6   ? -28.98493 -26.91379 27.96341  1.000 30.12590 ? 7   THR E CG2 1 
ATOM   4589 N N   . PRO E 5  7   ? -26.49611 -30.67973 28.24645  1.000 29.32544 ? 8   PRO E N   1 
ATOM   4590 C CA  . PRO E 5  7   ? -27.83882 -31.14208 28.61034  1.000 26.21307 ? 8   PRO E CA  1 
ATOM   4591 C C   . PRO E 5  7   ? -27.91873 -31.50353 30.08711  1.000 23.56185 ? 8   PRO E C   1 
ATOM   4592 O O   . PRO E 5  7   ? -26.88817 -31.72761 30.71946  1.000 25.47299 ? 8   PRO E O   1 
ATOM   4593 C CB  . PRO E 5  7   ? -28.05023 -32.37112 27.72109  1.000 25.34782 ? 8   PRO E CB  1 
ATOM   4594 C CG  . PRO E 5  7   ? -26.68742 -32.76593 27.22512  1.000 36.04001 ? 8   PRO E CG  1 
ATOM   4595 C CD  . PRO E 5  7   ? -25.67345 -31.75523 27.67181  1.000 28.59258 ? 8   PRO E CD  1 
ATOM   4596 N N   . ARG E 5  8   ? -29.13463 -31.55576 30.62908  1.000 22.70308 ? 9   ARG E N   1 
ATOM   4597 C CA  . ARG E 5  8   ? -29.29707 -31.77011 32.06184  1.000 24.09951 ? 9   ARG E CA  1 
ATOM   4598 C C   . ARG E 5  8   ? -29.06226 -33.22226 32.46153  1.000 24.90470 ? 9   ARG E C   1 
ATOM   4599 O O   . ARG E 5  8   ? -28.55237 -33.48197 33.55735  1.000 24.66576 ? 9   ARG E O   1 
ATOM   4600 C CB  . ARG E 5  8   ? -30.68904 -31.30805 32.49667  1.000 25.65623 ? 9   ARG E CB  1 
ATOM   4601 C CG  . ARG E 5  8   ? -30.94850 -29.83540 32.20646  1.000 27.89833 ? 9   ARG E CG  1 
ATOM   4602 C CD  . ARG E 5  8   ? -32.42410 -29.48676 32.30408  1.000 41.56228 ? 9   ARG E CD  1 
ATOM   4603 N NE  . ARG E 5  8   ? -32.93829 -29.67056 33.65586  1.000 41.02724 ? 9   ARG E NE  1 
ATOM   4604 C CZ  . ARG E 5  8   ? -33.97744 -30.43437 33.96357  1.000 42.86198 ? 9   ARG E CZ  1 
ATOM   4605 N NH1 . ARG E 5  8   ? -34.64863 -31.09553 33.03423  1.000 37.82916 ? 9   ARG E NH1 1 
ATOM   4606 N NH2 . ARG E 5  8   ? -34.35379 -30.53623 35.23517  1.000 43.89756 ? 9   ARG E NH2 1 
ATOM   4607 N N   . TYR E 5  9   ? -29.41773 -34.17273 31.59980  1.000 22.32578 ? 10  TYR E N   1 
ATOM   4608 C CA  . TYR E 5  9   ? -29.23304 -35.59045 31.87515  1.000 24.10053 ? 10  TYR E CA  1 
ATOM   4609 C C   . TYR E 5  9   ? -28.67449 -36.26272 30.63078  1.000 25.50324 ? 10  TYR E C   1 
ATOM   4610 O O   . TYR E 5  9   ? -29.03687 -35.89653 29.50955  1.000 27.04346 ? 10  TYR E O   1 
ATOM   4611 C CB  . TYR E 5  9   ? -30.55099 -36.26127 32.29139  1.000 24.54385 ? 10  TYR E CB  1 
ATOM   4612 C CG  . TYR E 5  9   ? -31.14930 -35.72080 33.57310  1.000 28.30523 ? 10  TYR E CG  1 
ATOM   4613 C CD1 . TYR E 5  9   ? -31.90590 -34.55589 33.57441  1.000 30.24315 ? 10  TYR E CD1 1 
ATOM   4614 C CD2 . TYR E 5  9   ? -30.96182 -36.37980 34.78094  1.000 28.11133 ? 10  TYR E CD2 1 
ATOM   4615 C CE1 . TYR E 5  9   ? -32.45371 -34.06017 34.74283  1.000 27.13986 ? 10  TYR E CE1 1 
ATOM   4616 C CE2 . TYR E 5  9   ? -31.50824 -35.89286 35.95368  1.000 32.49279 ? 10  TYR E CE2 1 
ATOM   4617 C CZ  . TYR E 5  9   ? -32.25343 -34.73359 35.92781  1.000 32.01647 ? 10  TYR E CZ  1 
ATOM   4618 O OH  . TYR E 5  9   ? -32.79811 -34.24463 37.09215  1.000 31.83897 ? 10  TYR E OH  1 
ATOM   4619 N N   . LEU E 5  10  ? -27.79463 -37.24468 30.83004  1.000 24.37750 ? 11  LEU E N   1 
ATOM   4620 C CA  . LEU E 5  10  ? -27.11935 -37.90144 29.71809  1.000 30.99407 ? 11  LEU E CA  1 
ATOM   4621 C C   . LEU E 5  10  ? -26.87504 -39.36874 30.03446  1.000 29.71815 ? 11  LEU E C   1 
ATOM   4622 O O   . LEU E 5  10  ? -26.52632 -39.71983 31.16494  1.000 25.29474 ? 11  LEU E O   1 
ATOM   4623 C CB  . LEU E 5  10  ? -25.77504 -37.23863 29.40076  1.000 32.99056 ? 11  LEU E CB  1 
ATOM   4624 C CG  . LEU E 5  10  ? -25.76115 -35.81904 28.84686  1.000 31.90263 ? 11  LEU E CG  1 
ATOM   4625 C CD1 . LEU E 5  10  ? -25.44165 -34.82744 29.95447  1.000 34.22834 ? 11  LEU E CD1 1 
ATOM   4626 C CD2 . LEU E 5  10  ? -24.74817 -35.71971 27.72531  1.000 31.73254 ? 11  LEU E CD2 1 
ATOM   4627 N N   . ILE E 5  11  ? -27.04512 -40.21434 29.02109  1.000 22.31713 ? 12  ILE E N   1 
ATOM   4628 C CA  . ILE E 5  11  ? -26.62408 -41.60926 29.06104  1.000 24.93107 ? 12  ILE E CA  1 
ATOM   4629 C C   . ILE E 5  11  ? -25.64937 -41.83536 27.91428  1.000 33.77599 ? 12  ILE E C   1 
ATOM   4630 O O   . ILE E 5  11  ? -25.97329 -41.55392 26.75420  1.000 31.15611 ? 12  ILE E O   1 
ATOM   4631 C CB  . ILE E 5  11  ? -27.81518 -42.57921 28.95677  1.000 28.44035 ? 12  ILE E CB  1 
ATOM   4632 C CG1 . ILE E 5  11  ? -28.71077 -42.47440 30.19285  1.000 31.48055 ? 12  ILE E CG1 1 
ATOM   4633 C CG2 . ILE E 5  11  ? -27.31980 -44.00802 28.77489  1.000 26.66554 ? 12  ILE E CG2 1 
ATOM   4634 C CD1 . ILE E 5  11  ? -30.12260 -42.97137 29.95946  1.000 29.46397 ? 12  ILE E CD1 1 
ATOM   4635 N N   . LYS E 5  12  ? -24.46022 -42.33587 28.23930  1.000 28.13480 ? 13  LYS E N   1 
ATOM   4636 C CA  . LYS E 5  12  ? -23.44100 -42.65092 27.25060  1.000 31.78640 ? 13  LYS E CA  1 
ATOM   4637 C C   . LYS E 5  12  ? -22.91628 -44.05743 27.50475  1.000 33.44605 ? 13  LYS E C   1 
ATOM   4638 O O   . LYS E 5  12  ? -22.98726 -44.57582 28.62176  1.000 25.94531 ? 13  LYS E O   1 
ATOM   4639 C CB  . LYS E 5  12  ? -22.27936 -41.64529 27.29441  1.000 25.65715 ? 13  LYS E CB  1 
ATOM   4640 C CG  . LYS E 5  12  ? -22.61447 -40.25455 26.77415  1.000 30.11192 ? 13  LYS E CG  1 
ATOM   4641 C CD  . LYS E 5  12  ? -23.09236 -40.29263 25.33104  1.000 32.79032 ? 13  LYS E CD  1 
ATOM   4642 C CE  . LYS E 5  12  ? -23.37974 -38.89330 24.80911  1.000 34.91970 ? 13  LYS E CE  1 
ATOM   4643 N NZ  . LYS E 5  12  ? -22.98907 -38.74257 23.37775  1.000 46.19660 ? 13  LYS E NZ  1 
ATOM   4644 N N   . THR E 5  13  ? -22.39091 -44.67623 26.45357  1.000 26.90818 ? 14  THR E N   1 
ATOM   4645 C CA  . THR E 5  13  ? -21.74935 -45.97764 26.56379  1.000 29.55897 ? 14  THR E CA  1 
ATOM   4646 C C   . THR E 5  13  ? -20.23441 -45.80727 26.60672  1.000 29.83126 ? 14  THR E C   1 
ATOM   4647 O O   . THR E 5  13  ? -19.69349 -44.78038 26.18920  1.000 28.17177 ? 14  THR E O   1 
ATOM   4648 C CB  . THR E 5  13  ? -22.15297 -46.89117 25.40165  1.000 29.60826 ? 14  THR E CB  1 
ATOM   4649 O OG1 . THR E 5  13  ? -21.88037 -46.23940 24.15563  1.000 30.90728 ? 14  THR E OG1 1 
ATOM   4650 C CG2 . THR E 5  13  ? -23.63807 -47.22128 25.47997  1.000 33.41643 ? 14  THR E CG2 1 
ATOM   4651 N N   . ARG E 5  14  ? -19.55263 -46.82436 27.13778  1.000 29.34454 ? 15  ARG E N   1 
ATOM   4652 C CA  . ARG E 5  14  ? -18.10537 -46.74011 27.29637  1.000 32.88866 ? 15  ARG E CA  1 
ATOM   4653 C C   . ARG E 5  14  ? -17.43050 -46.52346 25.94752  1.000 32.76956 ? 15  ARG E C   1 
ATOM   4654 O O   . ARG E 5  14  ? -17.84001 -47.09010 24.93046  1.000 32.75427 ? 15  ARG E O   1 
ATOM   4655 C CB  . ARG E 5  14  ? -17.54327 -48.00673 27.94686  1.000 36.17105 ? 15  ARG E CB  1 
ATOM   4656 C CG  . ARG E 5  14  ? -16.02562 -48.10737 27.77470  1.000 49.89090 ? 15  ARG E CG  1 
ATOM   4657 C CD  . ARG E 5  14  ? -15.42859 -49.42030 28.21873  1.000 57.33748 ? 15  ARG E CD  1 
ATOM   4658 N NE  . ARG E 5  14  ? -16.35151 -50.22000 29.00702  1.000 69.29547 ? 15  ARG E NE  1 
ATOM   4659 C CZ  . ARG E 5  14  ? -16.75971 -51.43182 28.66378  1.000 77.53876 ? 15  ARG E CZ  1 
ATOM   4660 N NH1 . ARG E 5  14  ? -16.39030 -51.98996 27.52324  1.000 71.63530 ? 15  ARG E NH1 1 
ATOM   4661 N NH2 . ARG E 5  14  ? -17.55329 -52.10201 29.48591  1.000 64.89338 ? 15  ARG E NH2 1 
ATOM   4662 N N   . GLY E 5  15  ? -16.38638 -45.69348 25.94612  1.000 33.98141 ? 16  GLY E N   1 
ATOM   4663 C CA  . GLY E 5  15  ? -15.64005 -45.39279 24.74795  1.000 32.88730 ? 16  GLY E CA  1 
ATOM   4664 C C   . GLY E 5  15  ? -16.16568 -44.21845 23.95792  1.000 35.21834 ? 16  GLY E C   1 
ATOM   4665 O O   . GLY E 5  15  ? -15.46811 -43.73508 23.05735  1.000 32.85244 ? 16  GLY E O   1 
ATOM   4666 N N   . GLN E 5  16  ? -17.36681 -43.74199 24.26642  1.000 31.38718 ? 17  GLN E N   1 
ATOM   4667 C CA  . GLN E 5  16  ? -17.94212 -42.61809 23.55268  1.000 31.49215 ? 17  GLN E CA  1 
ATOM   4668 C C   . GLN E 5  16  ? -17.32749 -41.30621 24.03124  1.000 32.05797 ? 17  GLN E C   1 
ATOM   4669 O O   . GLN E 5  16  ? -16.54102 -41.25775 24.98119  1.000 29.81259 ? 17  GLN E O   1 
ATOM   4670 C CB  . GLN E 5  16  ? -19.45658 -42.58202 23.74016  1.000 26.69572 ? 17  GLN E CB  1 
ATOM   4671 C CG  . GLN E 5  16  ? -20.21757 -43.62548 22.94740  1.000 29.37133 ? 17  GLN E CG  1 
ATOM   4672 C CD  . GLN E 5  16  ? -21.69035 -43.28725 22.82485  1.000 37.72398 ? 17  GLN E CD  1 
ATOM   4673 O OE1 . GLN E 5  16  ? -22.49093 -43.62789 23.69515  1.000 34.38024 ? 17  GLN E OE1 1 
ATOM   4674 N NE2 . GLN E 5  16  ? -22.05471 -42.61000 21.74231  1.000 46.26009 ? 17  GLN E NE2 1 
ATOM   4675 N N   . GLN E 5  17  ? -17.70953 -40.22966 23.35472  1.000 30.77498 ? 18  GLN E N   1 
ATOM   4676 C CA  . GLN E 5  17  ? -17.31170 -38.87746 23.70565  1.000 33.48934 ? 18  GLN E CA  1 
ATOM   4677 C C   . GLN E 5  17  ? -18.55416 -38.07313 24.06890  1.000 30.11470 ? 18  GLN E C   1 
ATOM   4678 O O   . GLN E 5  17  ? -19.66077 -38.37429 23.61182  1.000 29.20692 ? 18  GLN E O   1 
ATOM   4679 C CB  . GLN E 5  17  ? -16.54158 -38.22234 22.54408  1.000 36.38295 ? 18  GLN E CB  1 
ATOM   4680 C CG  . GLN E 5  17  ? -16.95468 -36.80287 22.20056  1.000 42.14399 ? 18  GLN E CG  1 
ATOM   4681 C CD  . GLN E 5  17  ? -16.32244 -36.30650 20.92068  1.000 40.55155 ? 18  GLN E CD  1 
ATOM   4682 O OE1 . GLN E 5  17  ? -15.82158 -37.09228 20.11641  1.000 58.13359 ? 18  GLN E OE1 1 
ATOM   4683 N NE2 . GLN E 5  17  ? -16.33382 -34.99300 20.72684  1.000 52.77807 ? 18  GLN E NE2 1 
ATOM   4684 N N   . VAL E 5  18  ? -18.37307 -37.05970 24.91427  1.000 27.55584 ? 19  VAL E N   1 
ATOM   4685 C CA  . VAL E 5  18  ? -19.47602 -36.21758 25.35789  1.000 32.44587 ? 19  VAL E CA  1 
ATOM   4686 C C   . VAL E 5  18  ? -19.01249 -34.76712 25.40127  1.000 27.92301 ? 19  VAL E C   1 
ATOM   4687 O O   . VAL E 5  18  ? -17.85392 -34.47304 25.70977  1.000 27.05986 ? 19  VAL E O   1 
ATOM   4688 C CB  . VAL E 5  18  ? -20.01516 -36.67282 26.73486  1.000 29.24868 ? 19  VAL E CB  1 
ATOM   4689 C CG1 . VAL E 5  18  ? -18.92403 -36.59085 27.79328  1.000 26.19202 ? 19  VAL E CG1 1 
ATOM   4690 C CG2 . VAL E 5  18  ? -21.22617 -35.85175 27.13960  1.000 27.68449 ? 19  VAL E CG2 1 
ATOM   4691 N N   . THR E 5  19  ? -19.92791 -33.85655 25.07152  1.000 25.66189 ? 20  THR E N   1 
ATOM   4692 C CA  . THR E 5  19  ? -19.68173 -32.42272 25.15002  1.000 25.09999 ? 20  THR E CA  1 
ATOM   4693 C C   . THR E 5  19  ? -20.79500 -31.77146 25.95742  1.000 28.32366 ? 20  THR E C   1 
ATOM   4694 O O   . THR E 5  19  ? -21.97697 -31.94976 25.64596  1.000 28.16031 ? 20  THR E O   1 
ATOM   4695 C CB  . THR E 5  19  ? -19.60008 -31.79109 23.75509  1.000 31.19782 ? 20  THR E CB  1 
ATOM   4696 O OG1 . THR E 5  19  ? -18.51257 -32.37535 23.02861  1.000 34.50440 ? 20  THR E OG1 1 
ATOM   4697 C CG2 . THR E 5  19  ? -19.38097 -30.28657 23.85948  1.000 24.87453 ? 20  THR E CG2 1 
ATOM   4698 N N   . LEU E 5  20  ? -20.41625 -31.02681 26.99325  1.000 22.43368 ? 21  LEU E N   1 
ATOM   4699 C CA  . LEU E 5  20  ? -21.35118 -30.29133 27.83084  1.000 25.41018 ? 21  LEU E CA  1 
ATOM   4700 C C   . LEU E 5  20  ? -21.16548 -28.79436 27.61842  1.000 21.96686 ? 21  LEU E C   1 
ATOM   4701 O O   . LEU E 5  20  ? -20.06177 -28.32699 27.32930  1.000 21.59571 ? 21  LEU E O   1 
ATOM   4702 C CB  . LEU E 5  20  ? -21.15613 -30.63640 29.31150  1.000 19.90415 ? 21  LEU E CB  1 
ATOM   4703 C CG  . LEU E 5  20  ? -21.05000 -32.12715 29.63689  1.000 22.30844 ? 21  LEU E CG  1 
ATOM   4704 C CD1 . LEU E 5  20  ? -20.65451 -32.33587 31.08721  1.000 19.94183 ? 21  LEU E CD1 1 
ATOM   4705 C CD2 . LEU E 5  20  ? -22.35805 -32.84071 29.32507  1.000 23.73122 ? 21  LEU E CD2 1 
ATOM   4706 N N   . SER E 5  21  ? -22.25460 -28.04248 27.76966  1.000 19.03915 ? 22  SER E N   1 
ATOM   4707 C CA  . SER E 5  21  ? -22.24746 -26.60898 27.51921  1.000 22.72606 ? 22  SER E CA  1 
ATOM   4708 C C   . SER E 5  21  ? -22.74584 -25.85793 28.74507  1.000 22.76293 ? 22  SER E C   1 
ATOM   4709 O O   . SER E 5  21  ? -23.53973 -26.37713 29.53447  1.000 22.65355 ? 22  SER E O   1 
ATOM   4710 C CB  . SER E 5  21  ? -23.11141 -26.24801 26.30235  1.000 29.20347 ? 22  SER E CB  1 
ATOM   4711 O OG  . SER E 5  21  ? -23.11441 -24.84888 26.08070  1.000 31.02168 ? 22  SER E OG  1 
ATOM   4712 N N   . CYS E 5  22  ? -22.27880 -24.61933 28.88744  1.000 22.60082 ? 23  CYS E N   1 
ATOM   4713 C CA  . CYS E 5  22  ? -22.61033 -23.79997 30.04828  1.000 25.35969 ? 23  CYS E CA  1 
ATOM   4714 C C   . CYS E 5  22  ? -22.62402 -22.33784 29.63433  1.000 25.69791 ? 23  CYS E C   1 
ATOM   4715 O O   . CYS E 5  22  ? -21.61728 -21.82621 29.13518  1.000 26.65502 ? 23  CYS E O   1 
ATOM   4716 C CB  . CYS E 5  22  ? -21.60635 -24.02800 31.18256  1.000 26.79437 ? 23  CYS E CB  1 
ATOM   4717 S SG  . CYS E 5  22  ? -21.63429 -22.77405 32.48825  1.000 29.73225 ? 23  CYS E SG  1 
ATOM   4718 N N   . SER E 5  23  ? -23.75668 -21.66890 29.84849  1.000 21.29431 ? 24  SER E N   1 
ATOM   4719 C CA  . SER E 5  23  ? -23.88180 -20.24360 29.57690  1.000 30.77218 ? 24  SER E CA  1 
ATOM   4720 C C   . SER E 5  23  ? -23.88573 -19.47936 30.89113  1.000 23.98849 ? 24  SER E C   1 
ATOM   4721 O O   . SER E 5  23  ? -24.76499 -19.71450 31.73278  1.000 25.99219 ? 24  SER E O   1 
ATOM   4722 C CB  . SER E 5  23  ? -25.15413 -19.95145 28.78310  1.000 28.73116 ? 24  SER E CB  1 
ATOM   4723 O OG  . SER E 5  23  ? -25.20008 -20.73080 27.60042  1.000 37.37839 ? 24  SER E OG  1 
ATOM   4724 N N   . PRO E 5  24  ? -22.94114 -18.56975 31.11231  1.000 24.28437 ? 25  PRO E N   1 
ATOM   4725 C CA  . PRO E 5  24  ? -22.84971 -17.89116 32.41034  1.000 24.19644 ? 25  PRO E CA  1 
ATOM   4726 C C   . PRO E 5  24  ? -23.94112 -16.84514 32.58739  1.000 26.19418 ? 25  PRO E C   1 
ATOM   4727 O O   . PRO E 5  24  ? -24.72437 -16.54620 31.68438  1.000 25.99043 ? 25  PRO E O   1 
ATOM   4728 C CB  . PRO E 5  24  ? -21.46315 -17.24224 32.37292  1.000 19.23204 ? 25  PRO E CB  1 
ATOM   4729 C CG  . PRO E 5  24  ? -21.16442 -17.07182 30.92402  1.000 25.57754 ? 25  PRO E CG  1 
ATOM   4730 C CD  . PRO E 5  24  ? -21.82383 -18.21962 30.21864  1.000 28.80078 ? 25  PRO E CD  1 
ATOM   4731 N N   . ILE E 5  25  ? -23.97952 -16.28754 33.80130  1.000 28.90775 ? 26  ILE E N   1 
ATOM   4732 C CA  . ILE E 5  25  ? -24.86462 -15.16635 34.08979  1.000 24.56555 ? 26  ILE E CA  1 
ATOM   4733 C C   . ILE E 5  25  ? -24.47580 -13.97922 33.21547  1.000 26.35925 ? 26  ILE E C   1 
ATOM   4734 O O   . ILE E 5  25  ? -23.29373 -13.76663 32.91124  1.000 24.24166 ? 26  ILE E O   1 
ATOM   4735 C CB  . ILE E 5  25  ? -24.79664 -14.82224 35.58914  1.000 24.34804 ? 26  ILE E CB  1 
ATOM   4736 C CG1 . ILE E 5  25  ? -25.60228 -15.83557 36.40535  1.000 27.71763 ? 26  ILE E CG1 1 
ATOM   4737 C CG2 . ILE E 5  25  ? -25.29793 -13.40982 35.87384  1.000 24.37793 ? 26  ILE E CG2 1 
ATOM   4738 C CD1 . ILE E 5  25  ? -25.24970 -15.84983 37.87468  1.000 20.48579 ? 26  ILE E CD1 1 
ATOM   4739 N N   . SER E 5  26  ? -25.47911 -13.21611 32.77997  1.000 24.34395 ? 27  SER E N   1 
ATOM   4740 C CA  . SER E 5  26  ? -25.24617 -12.02159 31.97447  1.000 25.38023 ? 27  SER E CA  1 
ATOM   4741 C C   . SER E 5  26  ? -24.26592 -11.08153 32.65940  1.000 26.76625 ? 27  SER E C   1 
ATOM   4742 O O   . SER E 5  26  ? -24.49159 -10.64899 33.79303  1.000 25.00613 ? 27  SER E O   1 
ATOM   4743 C CB  . SER E 5  26  ? -26.56958 -11.30117 31.71736  1.000 30.48563 ? 27  SER E CB  1 
ATOM   4744 O OG  . SER E 5  26  ? -26.34470 -10.03204 31.12620  1.000 32.07550 ? 27  SER E OG  1 
ATOM   4745 N N   . GLY E 5  27  ? -23.17691 -10.75823 31.96142  1.000 26.32449 ? 28  GLY E N   1 
ATOM   4746 C CA  . GLY E 5  27  ? -22.11957 -9.93665  32.49397  1.000 31.37540 ? 28  GLY E CA  1 
ATOM   4747 C C   . GLY E 5  27  ? -20.93104 -10.72098 33.01350  1.000 24.44981 ? 28  GLY E C   1 
ATOM   4748 O O   . GLY E 5  27  ? -19.80222 -10.21993 32.96731  1.000 29.43192 ? 28  GLY E O   1 
ATOM   4749 N N   . HIS E 5  28  ? -21.15887 -11.93798 33.50016  1.000 23.21799 ? 29  HIS E N   1 
ATOM   4750 C CA  . HIS E 5  28  ? -20.07872 -12.74548 34.05147  1.000 27.50152 ? 29  HIS E CA  1 
ATOM   4751 C C   . HIS E 5  28  ? -19.14867 -13.22446 32.93927  1.000 27.00907 ? 29  HIS E C   1 
ATOM   4752 O O   . HIS E 5  28  ? -19.59819 -13.66158 31.87696  1.000 26.55509 ? 29  HIS E O   1 
ATOM   4753 C CB  . HIS E 5  28  ? -20.66009 -13.93461 34.81632  1.000 23.90824 ? 29  HIS E CB  1 
ATOM   4754 C CG  . HIS E 5  28  ? -21.26714 -13.56345 36.13439  1.000 22.93519 ? 29  HIS E CG  1 
ATOM   4755 N ND1 . HIS E 5  28  ? -21.56019 -14.49308 37.10902  1.000 22.47024 ? 29  HIS E ND1 1 
ATOM   4756 C CD2 . HIS E 5  28  ? -21.63619 -12.36147 36.63848  1.000 23.67344 ? 29  HIS E CD2 1 
ATOM   4757 C CE1 . HIS E 5  28  ? -22.08534 -13.88041 38.15530  1.000 21.86842 ? 29  HIS E CE1 1 
ATOM   4758 N NE2 . HIS E 5  28  ? -22.14120 -12.58641 37.89586  1.000 23.42071 ? 29  HIS E NE2 1 
ATOM   4759 N N   . ARG E 5  29  ? -17.83907 -13.14156 33.18688  1.000 28.90929 ? 37  ARG E N   1 
ATOM   4760 C CA  . ARG E 5  29  ? -16.84144 -13.45737 32.17494  1.000 25.46531 ? 37  ARG E CA  1 
ATOM   4761 C C   . ARG E 5  29  ? -15.96168 -14.65091 32.54917  1.000 21.28791 ? 37  ARG E C   1 
ATOM   4762 O O   . ARG E 5  29  ? -15.16155 -15.08907 31.71612  1.000 25.52318 ? 37  ARG E O   1 
ATOM   4763 C CB  . ARG E 5  29  ? -15.95756 -12.21940 31.91572  1.000 21.38497 ? 37  ARG E CB  1 
ATOM   4764 C CG  . ARG E 5  29  ? -16.76971 -10.94402 31.57307  1.000 36.70643 ? 37  ARG E CG  1 
ATOM   4765 C CD  . ARG E 5  29  ? -16.52095 -10.20375 30.23572  1.000 50.80449 ? 37  ARG E CD  1 
ATOM   4766 N NE  . ARG E 5  29  ? -15.14048 -9.69442  30.09246  1.000 61.70800 ? 37  ARG E NE  1 
ATOM   4767 C CZ  . ARG E 5  29  ? -14.62081 -9.24275  28.95728  1.000 75.61395 ? 37  ARG E CZ  1 
ATOM   4768 N NH1 . ARG E 5  29  ? -15.38216 -9.05825  27.87966  1.000 81.62682 ? 37  ARG E NH1 1 
ATOM   4769 N NH2 . ARG E 5  29  ? -13.33870 -8.87627  28.93331  1.000 81.35053 ? 37  ARG E NH2 1 
ATOM   4770 N N   . SER E 5  30  ? -16.09300 -15.20265 33.75716  1.000 23.27491 ? 38  SER E N   1 
ATOM   4771 C CA  . SER E 5  30  ? -15.33785 -16.37946 34.17838  1.000 19.84379 ? 38  SER E CA  1 
ATOM   4772 C C   . SER E 5  30  ? -16.27396 -17.57352 34.30971  1.000 19.04447 ? 38  SER E C   1 
ATOM   4773 O O   . SER E 5  30  ? -17.34926 -17.46024 34.90452  1.000 22.51551 ? 38  SER E O   1 
ATOM   4774 C CB  . SER E 5  30  ? -14.61781 -16.13086 35.50667  1.000 22.04394 ? 38  SER E CB  1 
ATOM   4775 O OG  . SER E 5  30  ? -14.22321 -17.35301 36.11001  1.000 20.33701 ? 38  SER E OG  1 
ATOM   4776 N N   . VAL E 5  31  ? -15.86402 -18.71191 33.75414  1.000 21.04864 ? 39  VAL E N   1 
ATOM   4777 C CA  . VAL E 5  31  ? -16.60562 -19.96343 33.86054  1.000 18.06140 ? 39  VAL E CA  1 
ATOM   4778 C C   . VAL E 5  31  ? -15.64806 -21.04745 34.33590  1.000 23.75786 ? 39  VAL E C   1 
ATOM   4779 O O   . VAL E 5  31  ? -14.56068 -21.21150 33.77138  1.000 25.30849 ? 39  VAL E O   1 
ATOM   4780 C CB  . VAL E 5  31  ? -17.25497 -20.36974 32.52251  1.000 25.17855 ? 39  VAL E CB  1 
ATOM   4781 C CG1 . VAL E 5  31  ? -17.90655 -21.74128 32.64723  1.000 25.16232 ? 39  VAL E CG1 1 
ATOM   4782 C CG2 . VAL E 5  31  ? -18.27944 -19.32994 32.08286  1.000 18.18506 ? 39  VAL E CG2 1 
ATOM   4783 N N   . SER E 5  32  ? -16.05118 -21.78392 35.36785  1.000 20.26904 ? 40  SER E N   1 
ATOM   4784 C CA  . SER E 5  32  ? -15.26343 -22.87716 35.91558  1.000 22.31095 ? 40  SER E CA  1 
ATOM   4785 C C   . SER E 5  32  ? -16.07514 -24.16306 35.86821  1.000 21.83587 ? 40  SER E C   1 
ATOM   4786 O O   . SER E 5  32  ? -17.29982 -24.14437 36.01015  1.000 25.32313 ? 40  SER E O   1 
ATOM   4787 C CB  . SER E 5  32  ? -14.83796 -22.59242 37.36198  1.000 20.60987 ? 40  SER E CB  1 
ATOM   4788 O OG  . SER E 5  32  ? -14.31316 -21.28455 37.49236  1.000 28.67410 ? 40  SER E OG  1 
ATOM   4789 N N   . TRP E 5  33  ? -15.38337 -25.28177 35.67341  1.000 20.01909 ? 41  TRP E N   1 
ATOM   4790 C CA  . TRP E 5  33  ? -16.00941 -26.59441 35.59668  1.000 19.26901 ? 41  TRP E CA  1 
ATOM   4791 C C   . TRP E 5  33  ? -15.58124 -27.44956 36.78324  1.000 22.82093 ? 41  TRP E C   1 
ATOM   4792 O O   . TRP E 5  33  ? -14.40304 -27.46766 37.15477  1.000 18.37805 ? 41  TRP E O   1 
ATOM   4793 C CB  . TRP E 5  33  ? -15.64201 -27.30237 34.28893  1.000 18.58675 ? 41  TRP E CB  1 
ATOM   4794 C CG  . TRP E 5  33  ? -16.33341 -26.75311 33.07457  1.000 20.39607 ? 41  TRP E CG  1 
ATOM   4795 C CD1 . TRP E 5  33  ? -15.83390 -25.84164 32.18813  1.000 21.09630 ? 41  TRP E CD1 1 
ATOM   4796 C CD2 . TRP E 5  33  ? -17.64480 -27.09189 32.60425  1.000 20.07569 ? 41  TRP E CD2 1 
ATOM   4797 N NE1 . TRP E 5  33  ? -16.75507 -25.58834 31.19929  1.000 20.55652 ? 41  TRP E NE1 1 
ATOM   4798 C CE2 . TRP E 5  33  ? -17.87455 -26.34344 31.43137  1.000 22.41415 ? 41  TRP E CE2 1 
ATOM   4799 C CE3 . TRP E 5  33  ? -18.64830 -27.95085 33.06332  1.000 22.19446 ? 41  TRP E CE3 1 
ATOM   4800 C CZ2 . TRP E 5  33  ? -19.06418 -26.43031 30.71150  1.000 21.24482 ? 41  TRP E CZ2 1 
ATOM   4801 C CZ3 . TRP E 5  33  ? -19.82733 -28.03720 32.34607  1.000 21.02453 ? 41  TRP E CZ3 1 
ATOM   4802 C CH2 . TRP E 5  33  ? -20.02573 -27.28045 31.18326  1.000 20.73002 ? 41  TRP E CH2 1 
ATOM   4803 N N   . TYR E 5  34  ? -16.54320 -28.16452 37.36713  1.000 19.28747 ? 42  TYR E N   1 
ATOM   4804 C CA  . TYR E 5  34  ? -16.30486 -29.03511 38.50920  1.000 18.84831 ? 42  TYR E CA  1 
ATOM   4805 C C   . TYR E 5  34  ? -16.98373 -30.37822 38.28197  1.000 16.64833 ? 42  TYR E C   1 
ATOM   4806 O O   . TYR E 5  34  ? -18.03354 -30.45972 37.63925  1.000 21.84368 ? 42  TYR E O   1 
ATOM   4807 C CB  . TYR E 5  34  ? -16.82788 -28.41312 39.81895  1.000 19.90670 ? 42  TYR E CB  1 
ATOM   4808 C CG  . TYR E 5  34  ? -16.01163 -27.24465 40.31850  1.000 18.64598 ? 42  TYR E CG  1 
ATOM   4809 C CD1 . TYR E 5  34  ? -16.23796 -25.96068 39.84030  1.000 18.65463 ? 42  TYR E CD1 1 
ATOM   4810 C CD2 . TYR E 5  34  ? -15.01455 -27.42483 41.26817  1.000 19.38449 ? 42  TYR E CD2 1 
ATOM   4811 C CE1 . TYR E 5  34  ? -15.49342 -24.88875 40.29173  1.000 17.66008 ? 42  TYR E CE1 1 
ATOM   4812 C CE2 . TYR E 5  34  ? -14.26446 -26.35834 41.72821  1.000 19.09464 ? 42  TYR E CE2 1 
ATOM   4813 C CZ  . TYR E 5  34  ? -14.50738 -25.09353 41.23532  1.000 22.13040 ? 42  TYR E CZ  1 
ATOM   4814 O OH  . TYR E 5  34  ? -13.76398 -24.02911 41.68699  1.000 20.09696 ? 42  TYR E OH  1 
ATOM   4815 N N   . GLN E 5  35  ? -16.37804 -31.43190 38.82228  1.000 23.12998 ? 43  GLN E N   1 
ATOM   4816 C CA  . GLN E 5  35  ? -16.94705 -32.77283 38.79127  1.000 23.81712 ? 43  GLN E CA  1 
ATOM   4817 C C   . GLN E 5  35  ? -17.37456 -33.17503 40.19598  1.000 29.89112 ? 43  GLN E C   1 
ATOM   4818 O O   . GLN E 5  35  ? -16.59491 -33.05137 41.14680  1.000 24.18432 ? 43  GLN E O   1 
ATOM   4819 C CB  . GLN E 5  35  ? -15.94725 -33.79035 38.23809  1.000 23.78723 ? 43  GLN E CB  1 
ATOM   4820 C CG  . GLN E 5  35  ? -16.46625 -35.22091 38.25303  1.000 25.03136 ? 43  GLN E CG  1 
ATOM   4821 C CD  . GLN E 5  35  ? -15.36521 -36.24837 38.08246  1.000 27.62797 ? 43  GLN E CD  1 
ATOM   4822 O OE1 . GLN E 5  35  ? -14.47275 -36.36475 38.92128  1.000 27.83292 ? 43  GLN E OE1 1 
ATOM   4823 N NE2 . GLN E 5  35  ? -15.42447 -37.00246 36.99049  1.000 30.22663 ? 43  GLN E NE2 1 
ATOM   4824 N N   . GLN E 5  36  ? -18.60922 -33.65418 40.32058  1.000 29.37568 ? 44  GLN E N   1 
ATOM   4825 C CA  . GLN E 5  36  ? -19.15891 -34.13777 41.58588  1.000 29.44523 ? 44  GLN E CA  1 
ATOM   4826 C C   . GLN E 5  36  ? -19.49265 -35.61597 41.41171  1.000 29.62306 ? 44  GLN E C   1 
ATOM   4827 O O   . GLN E 5  36  ? -20.56503 -35.96685 40.90902  1.000 22.33357 ? 44  GLN E O   1 
ATOM   4828 C CB  . GLN E 5  36  ? -20.38736 -33.33191 41.99700  1.000 28.46446 ? 44  GLN E CB  1 
ATOM   4829 C CG  . GLN E 5  36  ? -21.09474 -33.84764 43.24330  1.000 37.03027 ? 44  GLN E CG  1 
ATOM   4830 C CD  . GLN E 5  36  ? -20.71434 -33.08063 44.49173  1.000 31.95831 ? 44  GLN E CD  1 
ATOM   4831 O OE1 . GLN E 5  36  ? -21.41543 -32.15486 44.89782  1.000 41.77356 ? 44  GLN E OE1 1 
ATOM   4832 N NE2 . GLN E 5  36  ? -19.60967 -33.46982 45.11635  1.000 32.07214 ? 44  GLN E NE2 1 
ATOM   4833 N N   . THR E 5  37  ? -18.56938 -36.47580 41.81550  1.000 31.69194 ? 45  THR E N   1 
ATOM   4834 C CA  . THR E 5  37  ? -18.70275 -37.92551 41.80536  1.000 38.05674 ? 45  THR E CA  1 
ATOM   4835 C C   . THR E 5  37  ? -19.30787 -38.39775 43.12611  1.000 41.52724 ? 45  THR E C   1 
ATOM   4836 O O   . THR E 5  37  ? -18.98713 -37.84458 44.18271  1.000 39.85873 ? 45  THR E O   1 
ATOM   4837 C CB  . THR E 5  37  ? -17.33928 -38.58159 41.59077  1.000 42.19753 ? 45  THR E CB  1 
ATOM   4838 O OG1 . THR E 5  37  ? -16.85037 -38.24855 40.28486  1.000 40.92107 ? 45  THR E OG1 1 
ATOM   4839 C CG2 . THR E 5  37  ? -17.42736 -40.08690 41.71290  1.000 40.45084 ? 45  THR E CG2 1 
ATOM   4840 N N   . PRO E 5  38  ? -20.21901 -39.38966 43.08927  1.000 37.43800 ? 46  PRO E N   1 
ATOM   4841 C CA  . PRO E 5  38  ? -20.79761 -39.91685 44.33469  1.000 45.71974 ? 46  PRO E CA  1 
ATOM   4842 C C   . PRO E 5  38  ? -19.76548 -40.23594 45.40656  1.000 44.21469 ? 46  PRO E C   1 
ATOM   4843 O O   . PRO E 5  38  ? -18.87218 -41.06390 45.19980  1.000 50.21012 ? 46  PRO E O   1 
ATOM   4844 C CB  . PRO E 5  38  ? -21.51979 -41.18395 43.86389  1.000 44.06474 ? 46  PRO E CB  1 
ATOM   4845 C CG  . PRO E 5  38  ? -21.94931 -40.85395 42.47571  1.000 44.52585 ? 46  PRO E CG  1 
ATOM   4846 C CD  . PRO E 5  38  ? -20.88111 -39.95149 41.89657  1.000 37.56359 ? 46  PRO E CD  1 
ATOM   4847 N N   . GLY E 5  39  ? -19.87875 -39.56371 46.54822  1.000 37.56321 ? 47  GLY E N   1 
ATOM   4848 C CA  . GLY E 5  39  ? -19.00856 -39.80912 47.68711  1.000 33.97834 ? 47  GLY E CA  1 
ATOM   4849 C C   . GLY E 5  39  ? -17.58829 -39.30698 47.53834  1.000 44.91400 ? 47  GLY E C   1 
ATOM   4850 O O   . GLY E 5  39  ? -16.64791 -40.00078 47.94612  1.000 51.21918 ? 47  GLY E O   1 
ATOM   4851 N N   . GLN E 5  40  ? -17.40390 -38.10729 46.98520  1.000 46.57107 ? 48  GLN E N   1 
ATOM   4852 C CA  . GLN E 5  40  ? -16.05671 -37.63380 46.68699  1.000 51.12030 ? 48  GLN E CA  1 
ATOM   4853 C C   . GLN E 5  40  ? -15.82608 -36.18202 47.09254  1.000 45.44515 ? 48  GLN E C   1 
ATOM   4854 O O   . GLN E 5  40  ? -14.79539 -35.85853 47.69204  1.000 56.47782 ? 48  GLN E O   1 
ATOM   4855 C CB  . GLN E 5  40  ? -15.76380 -37.80225 45.19427  1.000 44.46731 ? 48  GLN E CB  1 
ATOM   4856 C CG  . GLN E 5  40  ? -14.29365 -37.98275 44.86523  1.000 52.13400 ? 48  GLN E CG  1 
ATOM   4857 C CD  . GLN E 5  40  ? -14.07998 -38.74463 43.57308  1.000 50.06649 ? 48  GLN E CD  1 
ATOM   4858 O OE1 . GLN E 5  40  ? -13.96222 -38.15132 42.49962  1.000 47.23010 ? 48  GLN E OE1 1 
ATOM   4859 N NE2 . GLN E 5  40  ? -14.03188 -40.06865 43.66919  1.000 43.93698 ? 48  GLN E NE2 1 
ATOM   4860 N N   . GLY E 5  41  ? -16.76376 -35.30259 46.76729  1.000 36.68748 ? 49  GLY E N   1 
ATOM   4861 C CA  . GLY E 5  41  ? -16.54028 -33.88026 46.90618  1.000 40.37110 ? 49  GLY E CA  1 
ATOM   4862 C C   . GLY E 5  41  ? -16.11012 -33.24554 45.59185  1.000 36.11347 ? 49  GLY E C   1 
ATOM   4863 O O   . GLY E 5  41  ? -15.60176 -33.90429 44.68117  1.000 31.82668 ? 49  GLY E O   1 
ATOM   4864 N N   . LEU E 5  42  ? -16.32519 -31.93310 45.49591  1.000 29.95360 ? 50  LEU E N   1 
ATOM   4865 C CA  . LEU E 5  42  ? -16.07421 -31.22345 44.24612  1.000 28.45369 ? 50  LEU E CA  1 
ATOM   4866 C C   . LEU E 5  42  ? -14.60749 -31.30286 43.84726  1.000 28.27697 ? 50  LEU E C   1 
ATOM   4867 O O   . LEU E 5  42  ? -13.71202 -31.07503 44.66571  1.000 26.25505 ? 50  LEU E O   1 
ATOM   4868 C CB  . LEU E 5  42  ? -16.49654 -29.75931 44.35885  1.000 24.09744 ? 50  LEU E CB  1 
ATOM   4869 C CG  . LEU E 5  42  ? -17.92105 -29.41734 43.92146  1.000 33.73040 ? 50  LEU E CG  1 
ATOM   4870 C CD1 . LEU E 5  42  ? -18.94607 -29.90821 44.93931  1.000 42.17578 ? 50  LEU E CD1 1 
ATOM   4871 C CD2 . LEU E 5  42  ? -18.06370 -27.92327 43.65648  1.000 27.11174 ? 50  LEU E CD2 1 
ATOM   4872 N N   . GLN E 5  43  ? -14.36992 -31.61779 42.57608  1.000 25.94447 ? 51  GLN E N   1 
ATOM   4873 C CA  . GLN E 5  43  ? -13.03277 -31.67433 42.00305  1.000 21.60822 ? 51  GLN E CA  1 
ATOM   4874 C C   . GLN E 5  43  ? -12.93185 -30.65281 40.87989  1.000 21.57393 ? 51  GLN E C   1 
ATOM   4875 O O   . GLN E 5  43  ? -13.78141 -30.62218 39.98283  1.000 21.39100 ? 51  GLN E O   1 
ATOM   4876 C CB  . GLN E 5  43  ? -12.71393 -33.07811 41.48359  1.000 25.36718 ? 51  GLN E CB  1 
ATOM   4877 C CG  . GLN E 5  43  ? -12.99820 -34.18783 42.48319  1.000 24.25645 ? 51  GLN E CG  1 
ATOM   4878 C CD  . GLN E 5  43  ? -12.01366 -34.19135 43.63272  1.000 37.06005 ? 51  GLN E CD  1 
ATOM   4879 O OE1 . GLN E 5  43  ? -10.81200 -34.01567 43.43358  1.000 40.69170 ? 51  GLN E OE1 1 
ATOM   4880 N NE2 . GLN E 5  43  ? -12.51746 -34.39068 44.84544  1.000 40.46812 ? 51  GLN E NE2 1 
ATOM   4881 N N   . PHE E 5  44  ? -11.89053 -29.82784 40.93067  1.000 21.61418 ? 52  PHE E N   1 
ATOM   4882 C CA  . PHE E 5  44  ? -11.72375 -28.73268 39.98604  1.000 19.09173 ? 52  PHE E CA  1 
ATOM   4883 C C   . PHE E 5  44  ? -11.20123 -29.25355 38.65218  1.000 21.27459 ? 52  PHE E C   1 
ATOM   4884 O O   . PHE E 5  44  ? -10.22208 -30.00469 38.60872  1.000 21.19180 ? 52  PHE E O   1 
ATOM   4885 C CB  . PHE E 5  44  ? -10.76723 -27.69336 40.57020  1.000 21.33854 ? 52  PHE E CB  1 
ATOM   4886 C CG  . PHE E 5  44  ? -10.44052 -26.56134 39.63719  1.000 25.37106 ? 52  PHE E CG  1 
ATOM   4887 C CD1 . PHE E 5  44  ? -11.43452 -25.71751 39.16789  1.000 19.13789 ? 52  PHE E CD1 1 
ATOM   4888 C CD2 . PHE E 5  44  ? -9.12963  -26.32698 39.24935  1.000 20.65027 ? 52  PHE E CD2 1 
ATOM   4889 C CE1 . PHE E 5  44  ? -11.12719 -24.66744 38.31737  1.000 19.12078 ? 52  PHE E CE1 1 
ATOM   4890 C CE2 . PHE E 5  44  ? -8.81608  -25.28222 38.40130  1.000 22.19420 ? 52  PHE E CE2 1 
ATOM   4891 C CZ  . PHE E 5  44  ? -9.81453  -24.44911 37.93667  1.000 21.24321 ? 52  PHE E CZ  1 
ATOM   4892 N N   . LEU E 5  45  ? -11.85904 -28.85737 37.56327  1.000 19.02240 ? 53  LEU E N   1 
ATOM   4893 C CA  . LEU E 5  45  ? -11.39032 -29.22405 36.23272  1.000 22.57452 ? 53  LEU E CA  1 
ATOM   4894 C C   . LEU E 5  45  ? -10.55285 -28.10069 35.63537  1.000 20.89250 ? 53  LEU E C   1 
ATOM   4895 O O   . LEU E 5  45  ? -9.35094  -28.27423 35.41075  1.000 20.85542 ? 53  LEU E O   1 
ATOM   4896 C CB  . LEU E 5  45  ? -12.56778 -29.57017 35.31656  1.000 21.17418 ? 53  LEU E CB  1 
ATOM   4897 C CG  . LEU E 5  45  ? -13.11132 -30.99342 35.48164  1.000 26.34859 ? 53  LEU E CG  1 
ATOM   4898 C CD1 . LEU E 5  45  ? -14.62901 -30.99618 35.59124  1.000 28.46817 ? 53  LEU E CD1 1 
ATOM   4899 C CD2 . LEU E 5  45  ? -12.65203 -31.88053 34.33467  1.000 26.68072 ? 53  LEU E CD2 1 
ATOM   4900 N N   . PHE E 5  46  ? -11.17356 -26.95166 35.37257  1.000 22.25217 ? 54  PHE E N   1 
ATOM   4901 C CA  . PHE E 5  46  ? -10.46691 -25.79812 34.82512  1.000 22.23950 ? 54  PHE E CA  1 
ATOM   4902 C C   . PHE E 5  46  ? -11.36340 -24.57159 34.92001  1.000 18.44837 ? 54  PHE E C   1 
ATOM   4903 O O   . PHE E 5  46  ? -12.58535 -24.68180 35.05741  1.000 19.97386 ? 54  PHE E O   1 
ATOM   4904 C CB  . PHE E 5  46  ? -10.02929 -26.02412 33.36912  1.000 20.25636 ? 54  PHE E CB  1 
ATOM   4905 C CG  . PHE E 5  46  ? -10.81057 -27.08895 32.65139  1.000 20.31800 ? 54  PHE E CG  1 
ATOM   4906 C CD1 . PHE E 5  46  ? -12.16912 -26.93838 32.41666  1.000 25.03946 ? 54  PHE E CD1 1 
ATOM   4907 C CD2 . PHE E 5  46  ? -10.18223 -28.24060 32.20413  1.000 26.82665 ? 54  PHE E CD2 1 
ATOM   4908 C CE1 . PHE E 5  46  ? -12.88659 -27.91947 31.75195  1.000 20.60030 ? 54  PHE E CE1 1 
ATOM   4909 C CE2 . PHE E 5  46  ? -10.89327 -29.22490 31.53830  1.000 21.49390 ? 54  PHE E CE2 1 
ATOM   4910 C CZ  . PHE E 5  46  ? -12.24796 -29.06335 31.31283  1.000 23.39845 ? 54  PHE E CZ  1 
ATOM   4911 N N   . GLU E 5  47  ? -10.73305 -23.40011 34.84617  1.000 19.10070 ? 55  GLU E N   1 
ATOM   4912 C CA  . GLU E 5  47  ? -11.42066 -22.11721 34.78389  1.000 20.77223 ? 55  GLU E CA  1 
ATOM   4913 C C   . GLU E 5  47  ? -11.02974 -21.39455 33.50234  1.000 28.45750 ? 55  GLU E C   1 
ATOM   4914 O O   . GLU E 5  47  ? -9.87429  -21.46127 33.07107  1.000 24.19535 ? 55  GLU E O   1 
ATOM   4915 C CB  . GLU E 5  47  ? -11.08095 -21.23191 35.98904  1.000 17.24085 ? 55  GLU E CB  1 
ATOM   4916 C CG  . GLU E 5  47  ? -11.84222 -19.91219 36.00595  1.000 25.28866 ? 55  GLU E CG  1 
ATOM   4917 C CD  . GLU E 5  47  ? -11.20358 -18.86446 36.89503  1.000 29.75963 ? 55  GLU E CD  1 
ATOM   4918 O OE1 . GLU E 5  47  ? -10.26937 -19.20882 37.64627  1.000 32.66185 ? 55  GLU E OE1 1 
ATOM   4919 O OE2 . GLU E 5  47  ? -11.64525 -17.69553 36.84907  1.000 29.81355 ? 55  GLU E OE2 1 
ATOM   4920 N N   . TYR E 5  48  ? -11.98944 -20.69173 32.90356  1.000 21.19317 ? 56  TYR E N   1 
ATOM   4921 C CA  . TYR E 5  48  ? -11.75720 -19.95066 31.67217  1.000 25.13740 ? 56  TYR E CA  1 
ATOM   4922 C C   . TYR E 5  48  ? -12.16430 -18.49540 31.84920  1.000 21.87359 ? 56  TYR E C   1 
ATOM   4923 O O   . TYR E 5  48  ? -13.18616 -18.19523 32.47338  1.000 25.79434 ? 56  TYR E O   1 
ATOM   4924 C CB  . TYR E 5  48  ? -12.51771 -20.58160 30.49645  1.000 20.71498 ? 56  TYR E CB  1 
ATOM   4925 C CG  . TYR E 5  48  ? -11.90506 -21.88748 30.05263  1.000 27.54101 ? 56  TYR E CG  1 
ATOM   4926 C CD1 . TYR E 5  48  ? -12.16943 -23.06585 30.73690  1.000 23.79541 ? 56  TYR E CD1 1 
ATOM   4927 C CD2 . TYR E 5  48  ? -11.04261 -21.93973 28.96558  1.000 27.82167 ? 56  TYR E CD2 1 
ATOM   4928 C CE1 . TYR E 5  48  ? -11.60125 -24.26086 30.34691  1.000 27.51265 ? 56  TYR E CE1 1 
ATOM   4929 C CE2 . TYR E 5  48  ? -10.46928 -23.13369 28.56604  1.000 29.09824 ? 56  TYR E CE2 1 
ATOM   4930 C CZ  . TYR E 5  48  ? -10.75064 -24.29023 29.26366  1.000 29.88220 ? 56  TYR E CZ  1 
ATOM   4931 O OH  . TYR E 5  48  ? -10.18498 -25.48348 28.87994  1.000 29.80683 ? 56  TYR E OH  1 
ATOM   4932 N N   . PHE E 5  49  ? -11.35185 -17.59729 31.29707  1.000 21.25941 ? 57  PHE E N   1 
ATOM   4933 C CA  . PHE E 5  49  ? -11.62037 -16.16382 31.34190  1.000 22.05657 ? 57  PHE E CA  1 
ATOM   4934 C C   . PHE E 5  49  ? -11.10437 -15.55157 30.04912  1.000 30.47840 ? 57  PHE E C   1 
ATOM   4935 O O   . PHE E 5  49  ? -9.91355  -15.67034 29.74145  1.000 22.60930 ? 57  PHE E O   1 
ATOM   4936 C CB  . PHE E 5  49  ? -10.95222 -15.51773 32.55891  1.000 22.43314 ? 57  PHE E CB  1 
ATOM   4937 C CG  . PHE E 5  49  ? -11.31327 -14.07100 32.76106  1.000 24.18538 ? 57  PHE E CG  1 
ATOM   4938 C CD1 . PHE E 5  49  ? -12.41035 -13.71501 33.53114  1.000 23.35026 ? 57  PHE E CD1 1 
ATOM   4939 C CD2 . PHE E 5  49  ? -10.54768 -13.06677 32.19101  1.000 23.44440 ? 57  PHE E CD2 1 
ATOM   4940 C CE1 . PHE E 5  49  ? -12.73874 -12.38402 33.72410  1.000 22.08036 ? 57  PHE E CE1 1 
ATOM   4941 C CE2 . PHE E 5  49  ? -10.87195 -11.73653 32.37760  1.000 27.44084 ? 57  PHE E CE2 1 
ATOM   4942 C CZ  . PHE E 5  49  ? -11.96829 -11.39419 33.14587  1.000 23.80056 ? 57  PHE E CZ  1 
ATOM   4943 N N   . SER E 5  50  ? -11.99833 -14.91366 29.29245  1.000 28.88102 ? 58  SER E N   1 
ATOM   4944 C CA  . SER E 5  50  ? -11.64846 -14.29082 28.01452  1.000 32.28632 ? 58  SER E CA  1 
ATOM   4945 C C   . SER E 5  50  ? -11.02327 -15.29914 27.04762  1.000 26.00070 ? 58  SER E C   1 
ATOM   4946 O O   . SER E 5  50  ? -9.96337  -15.06095 26.46330  1.000 29.14309 ? 58  SER E O   1 
ATOM   4947 C CB  . SER E 5  50  ? -10.72334 -13.09105 28.22559  1.000 36.30653 ? 58  SER E CB  1 
ATOM   4948 O OG  . SER E 5  50  ? -9.37611  -13.45571 27.97930  1.000 43.22517 ? 58  SER E OG  1 
ATOM   4949 N N   . GLU E 5  51  ? -11.69188 -16.44347 26.89466  1.000 22.87287 ? 63  GLU E N   1 
ATOM   4950 C CA  . GLU E 5  51  ? -11.42744 -17.49027 25.90599  1.000 33.68844 ? 63  GLU E CA  1 
ATOM   4951 C C   . GLU E 5  51  ? -10.17009 -18.31031 26.17795  1.000 31.41538 ? 63  GLU E C   1 
ATOM   4952 O O   . GLU E 5  51  ? -9.90450  -19.26022 25.43221  1.000 31.12516 ? 63  GLU E O   1 
ATOM   4953 C CB  . GLU E 5  51  ? -11.33486 -16.93484 24.47636  1.000 27.71127 ? 63  GLU E CB  1 
ATOM   4954 C CG  . GLU E 5  51  ? -12.48538 -16.02494 24.08450  1.000 28.17054 ? 63  GLU E CG  1 
ATOM   4955 C CD  . GLU E 5  51  ? -12.23637 -15.31010 22.77098  1.000 50.80813 ? 63  GLU E CD  1 
ATOM   4956 O OE1 . GLU E 5  51  ? -12.11846 -15.99316 21.73106  1.000 51.68130 ? 63  GLU E OE1 1 
ATOM   4957 O OE2 . GLU E 5  51  ? -12.15212 -14.06375 22.78056  1.000 53.37394 ? 63  GLU E OE2 1 
ATOM   4958 N N   . THR E 5  52  ? -9.39246  -17.99432 27.20840  1.000 28.67220 ? 64  THR E N   1 
ATOM   4959 C CA  . THR E 5  52  ? -8.15466  -18.70662 27.49198  1.000 34.62256 ? 64  THR E CA  1 
ATOM   4960 C C   . THR E 5  52  ? -8.26725  -19.45290 28.81555  1.000 35.57069 ? 64  THR E C   1 
ATOM   4961 O O   . THR E 5  52  ? -8.80203  -18.92167 29.79575  1.000 26.85115 ? 64  THR E O   1 
ATOM   4962 C CB  . THR E 5  52  ? -6.96012  -17.74537 27.53340  1.000 30.92891 ? 64  THR E CB  1 
ATOM   4963 O OG1 . THR E 5  52  ? -7.00524  -16.97146 28.73768  1.000 45.05453 ? 64  THR E OG1 1 
ATOM   4964 C CG2 . THR E 5  52  ? -6.98954  -16.80514 26.33796  1.000 32.80796 ? 64  THR E CG2 1 
ATOM   4965 N N   . GLN E 5  53  ? -7.76955  -20.69035 28.83692  1.000 34.63200 ? 65  GLN E N   1 
ATOM   4966 C CA  . GLN E 5  53  ? -7.73543  -21.44833 30.07990  1.000 33.16788 ? 65  GLN E CA  1 
ATOM   4967 C C   . GLN E 5  53  ? -6.83395  -20.74892 31.08369  1.000 34.54537 ? 65  GLN E C   1 
ATOM   4968 O O   . GLN E 5  53  ? -5.69752  -20.38207 30.77244  1.000 39.04255 ? 65  GLN E O   1 
ATOM   4969 C CB  . GLN E 5  53  ? -7.25122  -22.87892 29.84161  1.000 33.41341 ? 65  GLN E CB  1 
ATOM   4970 C CG  . GLN E 5  53  ? -7.62623  -23.82443 30.98209  1.000 26.74231 ? 65  GLN E CG  1 
ATOM   4971 C CD  . GLN E 5  53  ? -6.86145  -25.13344 30.95201  1.000 28.29618 ? 65  GLN E CD  1 
ATOM   4972 O OE1 . GLN E 5  53  ? -5.69169  -25.19169 31.33118  1.000 33.71590 ? 65  GLN E OE1 1 
ATOM   4973 N NE2 . GLN E 5  53  ? -7.52501  -26.19567 30.51422  1.000 27.63362 ? 65  GLN E NE2 1 
ATOM   4974 N N   . ARG E 5  54  ? -7.35050  -20.56182 32.29300  1.000 30.86639 ? 66  ARG E N   1 
ATOM   4975 C CA  . ARG E 5  54  ? -6.67898  -19.77188 33.31278  1.000 35.05445 ? 66  ARG E CA  1 
ATOM   4976 C C   . ARG E 5  54  ? -5.96365  -20.63386 34.34453  1.000 38.27932 ? 66  ARG E C   1 
ATOM   4977 O O   . ARG E 5  54  ? -4.81358  -20.35837 34.69719  1.000 40.87898 ? 66  ARG E O   1 
ATOM   4978 C CB  . ARG E 5  54  ? -7.69915  -18.86254 33.99879  1.000 39.57103 ? 66  ARG E CB  1 
ATOM   4979 C CG  . ARG E 5  54  ? -7.07237  -17.71893 34.73122  1.000 41.24975 ? 66  ARG E CG  1 
ATOM   4980 C CD  . ARG E 5  54  ? -8.10989  -16.71538 35.15081  1.000 36.48280 ? 66  ARG E CD  1 
ATOM   4981 N NE  . ARG E 5  54  ? -7.48492  -15.60807 35.85898  1.000 37.74365 ? 66  ARG E NE  1 
ATOM   4982 C CZ  . ARG E 5  54  ? -6.96400  -14.54259 35.26846  1.000 29.34185 ? 66  ARG E CZ  1 
ATOM   4983 N NH1 . ARG E 5  54  ? -7.00392  -14.39158 33.95379  1.000 23.73357 ? 66  ARG E NH1 1 
ATOM   4984 N NH2 . ARG E 5  54  ? -6.39495  -13.60195 36.01613  1.000 21.70224 ? 66  ARG E NH2 1 
ATOM   4985 N N   . ASN E 5  55  ? -6.63212  -21.66972 34.84218  1.000 36.37815 ? 67  ASN E N   1 
ATOM   4986 C CA  . ASN E 5  55  ? -6.01754  -22.64146 35.73179  1.000 29.27718 ? 67  ASN E CA  1 
ATOM   4987 C C   . ASN E 5  55  ? -6.65866  -23.99286 35.45809  1.000 29.28997 ? 67  ASN E C   1 
ATOM   4988 O O   . ASN E 5  55  ? -7.74224  -24.07798 34.87444  1.000 25.36711 ? 67  ASN E O   1 
ATOM   4989 C CB  . ASN E 5  55  ? -6.16924  -22.24318 37.20571  1.000 38.16125 ? 67  ASN E CB  1 
ATOM   4990 C CG  . ASN E 5  55  ? -5.20580  -21.14210 37.61611  1.000 45.76920 ? 67  ASN E CG  1 
ATOM   4991 O OD1 . ASN E 5  55  ? -3.99298  -21.34857 37.66404  1.000 47.38635 ? 67  ASN E OD1 1 
ATOM   4992 N ND2 . ASN E 5  55  ? -5.74365  -19.96438 37.91502  1.000 44.09424 ? 67  ASN E ND2 1 
ATOM   4993 N N   . LYS E 5  56  ? -5.97617  -25.05367 35.88043  1.000 23.06076 ? 68  LYS E N   1 
ATOM   4994 C CA  . LYS E 5  56  ? -6.39107  -26.40774 35.54815  1.000 26.18760 ? 68  LYS E CA  1 
ATOM   4995 C C   . LYS E 5  56  ? -6.17369  -27.31876 36.74832  1.000 26.55453 ? 68  LYS E C   1 
ATOM   4996 O O   . LYS E 5  56  ? -5.24540  -27.12160 37.53682  1.000 25.59197 ? 68  LYS E O   1 
ATOM   4997 C CB  . LYS E 5  56  ? -5.62216  -26.92397 34.31785  1.000 28.48567 ? 68  LYS E CB  1 
ATOM   4998 C CG  . LYS E 5  56  ? -5.79962  -28.40173 34.01375  1.000 41.75036 ? 68  LYS E CG  1 
ATOM   4999 C CD  . LYS E 5  56  ? -4.47148  -29.05266 33.65519  1.000 47.73357 ? 68  LYS E CD  1 
ATOM   5000 C CE  . LYS E 5  56  ? -4.66489  -30.49063 33.19565  1.000 53.37507 ? 68  LYS E CE  1 
ATOM   5001 N NZ  . LYS E 5  56  ? -4.67189  -31.44635 34.34265  1.000 43.53993 ? 68  LYS E NZ  1 
ATOM   5002 N N   . GLY E 5  57  ? -7.04779  -28.31051 36.88395  1.000 29.54577 ? 69  GLY E N   1 
ATOM   5003 C CA  . GLY E 5  57  ? -6.95888  -29.30370 37.93764  1.000 28.61952 ? 69  GLY E CA  1 
ATOM   5004 C C   . GLY E 5  57  ? -6.06257  -30.46933 37.57770  1.000 33.83298 ? 69  GLY E C   1 
ATOM   5005 O O   . GLY E 5  57  ? -5.09847  -30.33464 36.81715  1.000 34.02367 ? 69  GLY E O   1 
ATOM   5006 N N   . ASN E 5  58  ? -6.39479  -31.64062 38.12519  1.000 28.16482 ? 70  ASN E N   1 
ATOM   5007 C CA  . ASN E 5  58  ? -5.56190  -32.83205 38.00906  1.000 29.26573 ? 70  ASN E CA  1 
ATOM   5008 C C   . ASN E 5  58  ? -6.16964  -33.89245 37.09713  1.000 26.01445 ? 70  ASN E C   1 
ATOM   5009 O O   . ASN E 5  58  ? -5.76832  -35.05880 37.15810  1.000 28.01826 ? 70  ASN E O   1 
ATOM   5010 C CB  . ASN E 5  58  ? -5.29904  -33.42523 39.39398  1.000 32.95058 ? 70  ASN E CB  1 
ATOM   5011 C CG  . ASN E 5  58  ? -4.72122  -32.41328 40.36038  1.000 41.68247 ? 70  ASN E CG  1 
ATOM   5012 O OD1 . ASN E 5  58  ? -3.65034  -31.85278 40.12406  1.000 46.51264 ? 70  ASN E OD1 1 
ATOM   5013 N ND2 . ASN E 5  58  ? -5.43138  -32.16968 41.45654  1.000 47.73069 ? 70  ASN E ND2 1 
ATOM   5014 N N   . PHE E 5  59  ? -7.12180  -33.51827 36.25543  1.000 26.72866 ? 71  PHE E N   1 
ATOM   5015 C CA  . PHE E 5  59  ? -7.75468  -34.51155 35.40463  1.000 30.10161 ? 71  PHE E CA  1 
ATOM   5016 C C   . PHE E 5  59  ? -6.86865  -34.83962 34.20183  1.000 30.09883 ? 71  PHE E C   1 
ATOM   5017 O O   . PHE E 5  59  ? -6.06979  -34.00727 33.76370  1.000 23.66203 ? 71  PHE E O   1 
ATOM   5018 C CB  . PHE E 5  59  ? -9.11717  -34.01368 34.93360  1.000 27.84441 ? 71  PHE E CB  1 
ATOM   5019 C CG  . PHE E 5  59  ? -10.18447 -34.09242 35.98956  1.000 25.31036 ? 71  PHE E CG  1 
ATOM   5020 C CD1 . PHE E 5  59  ? -10.24025 -33.15496 37.00882  1.000 19.83199 ? 71  PHE E CD1 1 
ATOM   5021 C CD2 . PHE E 5  59  ? -11.12418 -35.11010 35.96974  1.000 32.44396 ? 71  PHE E CD2 1 
ATOM   5022 C CE1 . PHE E 5  59  ? -11.21728 -33.22667 37.98436  1.000 23.54495 ? 71  PHE E CE1 1 
ATOM   5023 C CE2 . PHE E 5  59  ? -12.10550 -35.18749 36.94273  1.000 29.50375 ? 71  PHE E CE2 1 
ATOM   5024 C CZ  . PHE E 5  59  ? -12.15138 -34.24417 37.95146  1.000 29.18571 ? 71  PHE E CZ  1 
ATOM   5025 N N   . PRO E 5  60  ? -6.98222  -36.05913 33.65781  1.000 27.02458 ? 72  PRO E N   1 
ATOM   5026 C CA  . PRO E 5  60  ? -6.15314  -36.43220 32.50139  1.000 29.24362 ? 72  PRO E CA  1 
ATOM   5027 C C   . PRO E 5  60  ? -6.49404  -35.64826 31.24209  1.000 29.09954 ? 72  PRO E C   1 
ATOM   5028 O O   . PRO E 5  60  ? -7.44015  -34.85363 31.22588  1.000 30.31440 ? 72  PRO E O   1 
ATOM   5029 C CB  . PRO E 5  60  ? -6.44747  -37.92865 32.32680  1.000 27.14612 ? 72  PRO E CB  1 
ATOM   5030 C CG  . PRO E 5  60  ? -7.77580  -38.13476 32.97975  1.000 33.90607 ? 72  PRO E CG  1 
ATOM   5031 C CD  . PRO E 5  60  ? -7.79496  -37.18848 34.14170  1.000 25.84237 ? 72  PRO E CD  1 
ATOM   5032 N N   . GLY E 5  61  ? -5.72595  -35.88211 30.17476  1.000 27.85115 ? 74  GLY E N   1 
ATOM   5033 C CA  . GLY E 5  61  ? -5.85850  -35.11128 28.94966  1.000 23.81986 ? 74  GLY E CA  1 
ATOM   5034 C C   . GLY E 5  61  ? -7.17448  -35.29476 28.22105  1.000 26.62630 ? 74  GLY E C   1 
ATOM   5035 O O   . GLY E 5  61  ? -7.59781  -34.38649 27.49832  1.000 26.82754 ? 74  GLY E O   1 
ATOM   5036 N N   . ARG E 5  62  ? -7.83334  -36.44409 28.38767  1.000 25.18285 ? 75  ARG E N   1 
ATOM   5037 C CA  . ARG E 5  62  ? -9.10941  -36.65439 27.71221  1.000 30.63623 ? 75  ARG E CA  1 
ATOM   5038 C C   . ARG E 5  62  ? -10.20101 -35.71602 28.21322  1.000 29.72052 ? 75  ARG E C   1 
ATOM   5039 O O   . ARG E 5  62  ? -11.25087 -35.61774 27.56905  1.000 25.94424 ? 75  ARG E O   1 
ATOM   5040 C CB  . ARG E 5  62  ? -9.55687  -38.11113 27.85787  1.000 29.51108 ? 75  ARG E CB  1 
ATOM   5041 C CG  . ARG E 5  62  ? -9.64401  -38.61012 29.28550  1.000 30.72465 ? 75  ARG E CG  1 
ATOM   5042 C CD  . ARG E 5  62  ? -9.76194  -40.12568 29.32187  1.000 27.87525 ? 75  ARG E CD  1 
ATOM   5043 N NE  . ARG E 5  62  ? -10.08002 -40.60963 30.65895  1.000 31.01054 ? 75  ARG E NE  1 
ATOM   5044 C CZ  . ARG E 5  62  ? -11.31068 -40.73449 31.13525  1.000 33.37462 ? 75  ARG E CZ  1 
ATOM   5045 N NH1 . ARG E 5  62  ? -12.36942 -40.43942 30.39888  1.000 21.98739 ? 75  ARG E NH1 1 
ATOM   5046 N NH2 . ARG E 5  62  ? -11.48330 -41.16659 32.38124  1.000 25.64890 ? 75  ARG E NH2 1 
ATOM   5047 N N   . PHE E 5  63  ? -9.98046  -35.03176 29.33423  1.000 23.88713 ? 76  PHE E N   1 
ATOM   5048 C CA  . PHE E 5  63  ? -10.85869 -33.96111 29.78763  1.000 23.61244 ? 76  PHE E CA  1 
ATOM   5049 C C   . PHE E 5  63  ? -10.32398 -32.63746 29.25181  1.000 23.85498 ? 76  PHE E C   1 
ATOM   5050 O O   . PHE E 5  63  ? -9.22366  -32.21366 29.62181  1.000 28.22927 ? 76  PHE E O   1 
ATOM   5051 C CB  . PHE E 5  63  ? -10.93722 -33.92301 31.31434  1.000 25.28940 ? 76  PHE E CB  1 
ATOM   5052 C CG  . PHE E 5  63  ? -11.55139 -35.15099 31.93081  1.000 27.34789 ? 76  PHE E CG  1 
ATOM   5053 C CD1 . PHE E 5  63  ? -10.81450 -36.31641 32.07637  1.000 25.01530 ? 76  PHE E CD1 1 
ATOM   5054 C CD2 . PHE E 5  63  ? -12.86250 -35.13288 32.38104  1.000 25.96124 ? 76  PHE E CD2 1 
ATOM   5055 C CE1 . PHE E 5  63  ? -11.37733 -37.44330 32.64886  1.000 29.17875 ? 76  PHE E CE1 1 
ATOM   5056 C CE2 . PHE E 5  63  ? -13.43099 -36.25621 32.95495  1.000 27.94171 ? 76  PHE E CE2 1 
ATOM   5057 C CZ  . PHE E 5  63  ? -12.68696 -37.41198 33.09036  1.000 31.10876 ? 76  PHE E CZ  1 
ATOM   5058 N N   . SER E 5  64  ? -11.09576 -31.98814 28.38342  1.000 20.17256 ? 77  SER E N   1 
ATOM   5059 C CA  . SER E 5  64  ? -10.68086 -30.73220 27.77683  1.000 23.64173 ? 77  SER E CA  1 
ATOM   5060 C C   . SER E 5  64  ? -11.84596 -29.75371 27.79734  1.000 24.61313 ? 77  SER E C   1 
ATOM   5061 O O   . SER E 5  64  ? -13.00744 -30.14412 27.93403  1.000 24.55860 ? 77  SER E O   1 
ATOM   5062 C CB  . SER E 5  64  ? -10.18037 -30.94165 26.34060  1.000 20.27135 ? 77  SER E CB  1 
ATOM   5063 O OG  . SER E 5  64  ? -11.25285 -31.27267 25.47642  1.000 24.48213 ? 77  SER E OG  1 
ATOM   5064 N N   . GLY E 5  65  ? -11.52097 -28.46659 27.65766  1.000 26.58662 ? 78  GLY E N   1 
ATOM   5065 C CA  . GLY E 5  65  ? -12.53455 -27.43090 27.67569  1.000 27.76218 ? 78  GLY E CA  1 
ATOM   5066 C C   . GLY E 5  65  ? -12.16313 -26.25956 26.79131  1.000 28.65163 ? 78  GLY E C   1 
ATOM   5067 O O   . GLY E 5  65  ? -11.05730 -26.18150 26.25079  1.000 23.36273 ? 78  GLY E O   1 
ATOM   5068 N N   . ARG E 5  66  ? -13.11212 -25.33395 26.66121  1.000 23.70508 ? 79  ARG E N   1 
ATOM   5069 C CA  . ARG E 5  66  ? -12.92844 -24.13891 25.84905  1.000 30.70150 ? 79  ARG E CA  1 
ATOM   5070 C C   . ARG E 5  66  ? -13.98917 -23.11543 26.23141  1.000 28.37480 ? 79  ARG E C   1 
ATOM   5071 O O   . ARG E 5  66  ? -15.06104 -23.47137 26.72709  1.000 26.10935 ? 79  ARG E O   1 
ATOM   5072 C CB  . ARG E 5  66  ? -13.00905 -24.46131 24.35005  1.000 25.72330 ? 79  ARG E CB  1 
ATOM   5073 C CG  . ARG E 5  66  ? -14.40834 -24.81286 23.86423  1.000 31.82193 ? 79  ARG E CG  1 
ATOM   5074 C CD  . ARG E 5  66  ? -14.37195 -25.59983 22.55996  1.000 53.75231 ? 79  ARG E CD  1 
ATOM   5075 N NE  . ARG E 5  66  ? -14.76736 -26.99077 22.75175  1.000 64.70685 ? 79  ARG E NE  1 
ATOM   5076 C CZ  . ARG E 5  66  ? -15.35401 -27.73917 21.82716  1.000 66.80040 ? 79  ARG E CZ  1 
ATOM   5077 N NH1 . ARG E 5  66  ? -15.63068 -27.26181 20.62431  1.000 65.92131 ? 79  ARG E NH1 1 
ATOM   5078 N NH2 . ARG E 5  66  ? -15.67290 -28.99777 22.11730  1.000 49.98922 ? 79  ARG E NH2 1 
ATOM   5079 N N   . GLN E 5  67  ? -13.67540 -21.84123 25.99884  1.000 25.42135 ? 80  GLN E N   1 
ATOM   5080 C CA  . GLN E 5  67  ? -14.61020 -20.74357 26.21607  1.000 25.59112 ? 80  GLN E CA  1 
ATOM   5081 C C   . GLN E 5  67  ? -14.65499 -19.87394 24.96952  1.000 22.64610 ? 80  GLN E C   1 
ATOM   5082 O O   . GLN E 5  67  ? -13.60727 -19.50823 24.42781  1.000 22.72778 ? 80  GLN E O   1 
ATOM   5083 C CB  . GLN E 5  67  ? -14.21619 -19.89657 27.42914  1.000 21.63287 ? 80  GLN E CB  1 
ATOM   5084 C CG  . GLN E 5  67  ? -15.22268 -18.80926 27.77179  1.000 19.34580 ? 80  GLN E CG  1 
ATOM   5085 C CD  . GLN E 5  67  ? -14.75176 -17.91053 28.90018  1.000 27.95028 ? 80  GLN E CD  1 
ATOM   5086 O OE1 . GLN E 5  67  ? -13.59975 -17.47204 28.92198  1.000 24.16745 ? 80  GLN E OE1 1 
ATOM   5087 N NE2 . GLN E 5  67  ? -15.64408 -17.62927 29.84513  1.000 21.60312 ? 80  GLN E NE2 1 
ATOM   5088 N N   . PHE E 5  68  ? -15.86440 -19.53515 24.52768  1.000 30.20209 ? 81  PHE E N   1 
ATOM   5089 C CA  . PHE E 5  68  ? -16.05942 -18.77028 23.30707  1.000 28.59550 ? 81  PHE E CA  1 
ATOM   5090 C C   . PHE E 5  68  ? -16.08389 -17.27094 23.60584  1.000 35.53110 ? 81  PHE E C   1 
ATOM   5091 O O   . PHE E 5  68  ? -15.94194 -16.83031 24.74992  1.000 29.85083 ? 81  PHE E O   1 
ATOM   5092 C CB  . PHE E 5  68  ? -17.34286 -19.21344 22.60596  1.000 26.50936 ? 81  PHE E CB  1 
ATOM   5093 C CG  . PHE E 5  68  ? -17.40561 -20.68990 22.33544  1.000 34.33880 ? 81  PHE E CG  1 
ATOM   5094 C CD1 . PHE E 5  68  ? -16.75062 -21.23685 21.24306  1.000 33.36657 ? 81  PHE E CD1 1 
ATOM   5095 C CD2 . PHE E 5  68  ? -18.11638 -21.53181 23.17406  1.000 30.19480 ? 81  PHE E CD2 1 
ATOM   5096 C CE1 . PHE E 5  68  ? -16.80615 -22.59670 20.99252  1.000 33.22715 ? 81  PHE E CE1 1 
ATOM   5097 C CE2 . PHE E 5  68  ? -18.17507 -22.89160 22.92957  1.000 34.36260 ? 81  PHE E CE2 1 
ATOM   5098 C CZ  . PHE E 5  68  ? -17.51982 -23.42462 21.83687  1.000 35.95295 ? 81  PHE E CZ  1 
ATOM   5099 N N   . SER E 5  69  ? -16.27985 -16.47400 22.55146  1.000 28.79280 ? 83  SER E N   1 
ATOM   5100 C CA  . SER E 5  69  ? -16.22680 -15.02106 22.67437  1.000 33.77756 ? 83  SER E CA  1 
ATOM   5101 C C   . SER E 5  69  ? -17.43516 -14.44817 23.40048  1.000 28.61241 ? 83  SER E C   1 
ATOM   5102 O O   . SER E 5  69  ? -17.37468 -13.30689 23.86863  1.000 39.04582 ? 83  SER E O   1 
ATOM   5103 C CB  . SER E 5  69  ? -16.10624 -14.38113 21.28968  1.000 37.02067 ? 83  SER E CB  1 
ATOM   5104 O OG  . SER E 5  69  ? -14.97962 -13.52530 21.22414  1.000 50.22567 ? 83  SER E OG  1 
ATOM   5105 N N   . ASN E 5  70  ? -18.52683 -15.20168 23.49505  1.000 25.79617 ? 84  ASN E N   1 
ATOM   5106 C CA  . ASN E 5  70  ? -19.70056 -14.78903 24.24973  1.000 33.52711 ? 84  ASN E CA  1 
ATOM   5107 C C   . ASN E 5  70  ? -19.65186 -15.23203 25.71258  1.000 29.89675 ? 84  ASN E C   1 
ATOM   5108 O O   . ASN E 5  70  ? -20.67819 -15.16516 26.39580  1.000 28.73579 ? 84  ASN E O   1 
ATOM   5109 C CB  . ASN E 5  70  ? -20.96785 -15.33288 23.58242  1.000 27.13578 ? 84  ASN E CB  1 
ATOM   5110 C CG  . ASN E 5  70  ? -20.94405 -16.84158 23.42804  1.000 36.49332 ? 84  ASN E CG  1 
ATOM   5111 O OD1 . ASN E 5  70  ? -19.95161 -17.49443 23.75245  1.000 35.16212 ? 84  ASN E OD1 1 
ATOM   5112 N ND2 . ASN E 5  70  ? -22.04064 -17.40422 22.93005  1.000 33.99462 ? 84  ASN E ND2 1 
ATOM   5113 N N   . SER E 5  71  ? -18.48873 -15.67407 26.20051  1.000 33.43130 ? 85  SER E N   1 
ATOM   5114 C CA  . SER E 5  71  ? -18.24261 -16.24990 27.52799  1.000 26.87846 ? 85  SER E CA  1 
ATOM   5115 C C   . SER E 5  71  ? -18.83850 -17.63274 27.73345  1.000 27.65638 ? 85  SER E C   1 
ATOM   5116 O O   . SER E 5  71  ? -18.61243 -18.22603 28.79717  1.000 26.30640 ? 85  SER E O   1 
ATOM   5117 C CB  . SER E 5  71  ? -18.73584 -15.37105 28.68632  1.000 29.70658 ? 85  SER E CB  1 
ATOM   5118 O OG  . SER E 5  71  ? -17.83815 -14.31945 28.96127  1.000 29.52747 ? 85  SER E OG  1 
ATOM   5119 N N   . ARG E 5  72  ? -19.60000 -18.16272 26.78325  1.000 25.61214 ? 86  ARG E N   1 
ATOM   5120 C CA  . ARG E 5  72  ? -20.08699 -19.52560 26.91861  1.000 27.97256 ? 86  ARG E CA  1 
ATOM   5121 C C   . ARG E 5  72  ? -18.91017 -20.49516 26.89872  1.000 25.25338 ? 86  ARG E C   1 
ATOM   5122 O O   . ARG E 5  72  ? -17.88235 -20.24648 26.26282  1.000 23.91541 ? 86  ARG E O   1 
ATOM   5123 C CB  . ARG E 5  72  ? -21.07873 -19.85230 25.80135  1.000 30.47208 ? 86  ARG E CB  1 
ATOM   5124 C CG  . ARG E 5  72  ? -21.71273 -21.23203 25.90070  1.000 26.93787 ? 86  ARG E CG  1 
ATOM   5125 C CD  . ARG E 5  72  ? -22.78658 -21.43236 24.83807  1.000 29.89092 ? 86  ARG E CD  1 
ATOM   5126 N NE  . ARG E 5  72  ? -22.21599 -21.54428 23.50105  1.000 38.58196 ? 86  ARG E NE  1 
ATOM   5127 C CZ  . ARG E 5  72  ? -21.85399 -22.68600 22.93131  1.000 40.96132 ? 86  ARG E CZ  1 
ATOM   5128 N NH1 . ARG E 5  72  ? -21.99940 -23.84580 23.55173  1.000 35.87259 ? 86  ARG E NH1 1 
ATOM   5129 N NH2 . ARG E 5  72  ? -21.32864 -22.66308 21.70960  1.000 41.51629 ? 86  ARG E NH2 1 
ATOM   5130 N N   . SER E 5  73  ? -19.05548 -21.59955 27.62456  1.000 20.60770 ? 87  SER E N   1 
ATOM   5131 C CA  . SER E 5  73  ? -17.97802 -22.56333 27.77278  1.000 24.41061 ? 87  SER E CA  1 
ATOM   5132 C C   . SER E 5  73  ? -18.48448 -23.96660 27.48204  1.000 23.77758 ? 87  SER E C   1 
ATOM   5133 O O   . SER E 5  73  ? -19.65559 -24.28361 27.70556  1.000 23.85324 ? 87  SER E O   1 
ATOM   5134 C CB  . SER E 5  73  ? -17.36952 -22.51172 29.18014  1.000 18.91826 ? 87  SER E CB  1 
ATOM   5135 O OG  . SER E 5  73  ? -16.31898 -23.45207 29.31538  1.000 21.68398 ? 87  SER E OG  1 
ATOM   5136 N N   . GLU E 5  74  ? -17.58054 -24.80240 26.97804  1.000 22.13081 ? 88  GLU E N   1 
ATOM   5137 C CA  . GLU E 5  74  ? -17.85284 -26.20382 26.70059  1.000 25.14613 ? 88  GLU E CA  1 
ATOM   5138 C C   . GLU E 5  74  ? -16.73159 -27.05221 27.28010  1.000 27.28547 ? 88  GLU E C   1 
ATOM   5139 O O   . GLU E 5  74  ? -15.56857 -26.64014 27.27253  1.000 26.30220 ? 88  GLU E O   1 
ATOM   5140 C CB  . GLU E 5  74  ? -17.97095 -26.46452 25.19016  1.000 22.87108 ? 88  GLU E CB  1 
ATOM   5141 C CG  . GLU E 5  74  ? -19.35632 -26.23075 24.61349  1.000 29.43642 ? 88  GLU E CG  1 
ATOM   5142 C CD  . GLU E 5  74  ? -19.39430 -26.39081 23.10319  1.000 35.76367 ? 88  GLU E CD  1 
ATOM   5143 O OE1 . GLU E 5  74  ? -18.43475 -26.95420 22.53609  1.000 35.20410 ? 88  GLU E OE1 1 
ATOM   5144 O OE2 . GLU E 5  74  ? -20.38709 -25.95679 22.48321  1.000 36.78567 ? 88  GLU E OE2 1 
ATOM   5145 N N   . MET E 5  75  ? -17.08010 -28.23292 27.78784  1.000 23.06195 ? 89  MET E N   1 
ATOM   5146 C CA  . MET E 5  75  ? -16.08665 -29.21296 28.20088  1.000 24.41124 ? 89  MET E CA  1 
ATOM   5147 C C   . MET E 5  75  ? -16.38432 -30.53809 27.51416  1.000 22.90381 ? 89  MET E C   1 
ATOM   5148 O O   . MET E 5  75  ? -17.53821 -30.85282 27.20939  1.000 23.19523 ? 89  MET E O   1 
ATOM   5149 C CB  . MET E 5  75  ? -16.04053 -29.39724 29.73478  1.000 21.15677 ? 89  MET E CB  1 
ATOM   5150 C CG  . MET E 5  75  ? -17.28020 -30.02429 30.36058  1.000 24.26315 ? 89  MET E CG  1 
ATOM   5151 S SD  . MET E 5  75  ? -16.93405 -30.71425 31.99946  1.000 25.42424 ? 89  MET E SD  1 
ATOM   5152 C CE  . MET E 5  75  ? -16.30346 -32.33254 31.56085  1.000 27.39464 ? 89  MET E CE  1 
ATOM   5153 N N   . ASN E 5  76  ? -15.32686 -31.30825 27.26507  1.000 22.74033 ? 90  ASN E N   1 
ATOM   5154 C CA  . ASN E 5  76  ? -15.41854 -32.53953 26.49442  1.000 25.69833 ? 90  ASN E CA  1 
ATOM   5155 C C   . ASN E 5  76  ? -14.61064 -33.63379 27.17615  1.000 27.48758 ? 90  ASN E C   1 
ATOM   5156 O O   . ASN E 5  76  ? -13.52340 -33.37733 27.70151  1.000 24.17756 ? 90  ASN E O   1 
ATOM   5157 C CB  . ASN E 5  76  ? -14.91270 -32.32585 25.05690  1.000 29.65878 ? 90  ASN E CB  1 
ATOM   5158 C CG  . ASN E 5  76  ? -14.92982 -33.60098 24.22809  1.000 34.24333 ? 90  ASN E CG  1 
ATOM   5159 O OD1 . ASN E 5  76  ? -15.90799 -33.89573 23.53775  1.000 27.75836 ? 90  ASN E OD1 1 
ATOM   5160 N ND2 . ASN E 5  76  ? -13.84055 -34.36010 24.28760  1.000 30.49859 ? 90  ASN E ND2 1 
ATOM   5161 N N   . VAL E 5  77  ? -15.15122 -34.85107 27.16928  1.000 26.62662 ? 91  VAL E N   1 
ATOM   5162 C CA  . VAL E 5  77  ? -14.44348 -36.04311 27.62385  1.000 33.70675 ? 91  VAL E CA  1 
ATOM   5163 C C   . VAL E 5  77  ? -14.37795 -37.01803 26.45516  1.000 35.67194 ? 91  VAL E C   1 
ATOM   5164 O O   . VAL E 5  77  ? -15.40979 -37.34750 25.85931  1.000 34.35874 ? 91  VAL E O   1 
ATOM   5165 C CB  . VAL E 5  77  ? -15.12289 -36.68650 28.84667  1.000 32.27879 ? 91  VAL E CB  1 
ATOM   5166 C CG1 . VAL E 5  77  ? -14.15102 -37.61468 29.55989  1.000 28.43570 ? 91  VAL E CG1 1 
ATOM   5167 C CG2 . VAL E 5  77  ? -15.63979 -35.61612 29.79800  1.000 25.25019 ? 91  VAL E CG2 1 
ATOM   5168 N N   . SER E 5  78  ? -13.16791 -37.48720 26.13996  1.000 33.92370 ? 92  SER E N   1 
ATOM   5169 C CA  . SER E 5  78  ? -12.91662 -38.14856 24.86012  1.000 38.97096 ? 92  SER E CA  1 
ATOM   5170 C C   . SER E 5  78  ? -13.39971 -39.59639 24.84748  1.000 44.56890 ? 92  SER E C   1 
ATOM   5171 O O   . SER E 5  78  ? -14.24149 -39.97265 24.02507  1.000 58.56585 ? 92  SER E O   1 
ATOM   5172 C CB  . SER E 5  78  ? -11.42334 -38.08617 24.52525  1.000 31.22372 ? 92  SER E CB  1 
ATOM   5173 O OG  . SER E 5  78  ? -10.97817 -36.74530 24.42231  1.000 50.93042 ? 92  SER E OG  1 
ATOM   5174 N N   . THR E 5  79  ? -12.85194 -40.43200 25.72602  1.000 35.95943 ? 93  THR E N   1 
ATOM   5175 C CA  . THR E 5  79  ? -13.14641 -41.86511 25.74997  1.000 35.28646 ? 93  THR E CA  1 
ATOM   5176 C C   . THR E 5  79  ? -13.68306 -42.20315 27.13724  1.000 37.77624 ? 93  THR E C   1 
ATOM   5177 O O   . THR E 5  79  ? -12.91753 -42.49161 28.06033  1.000 36.05064 ? 93  THR E O   1 
ATOM   5178 C CB  . THR E 5  79  ? -11.90694 -42.69296 25.40244  1.000 34.15772 ? 93  THR E CB  1 
ATOM   5179 O OG1 . THR E 5  79  ? -10.84451 -42.37298 26.30882  1.000 53.52783 ? 93  THR E OG1 1 
ATOM   5180 C CG2 . THR E 5  79  ? -11.45599 -42.39163 23.98678  1.000 42.88700 ? 93  THR E CG2 1 
ATOM   5181 N N   . LEU E 5  80  ? -15.00680 -42.17825 27.26796  1.000 27.60388 ? 94  LEU E N   1 
ATOM   5182 C CA  . LEU E 5  80  ? -15.64724 -42.28743 28.57099  1.000 30.21976 ? 94  LEU E CA  1 
ATOM   5183 C C   . LEU E 5  80  ? -15.44512 -43.66600 29.18685  1.000 29.80877 ? 94  LEU E C   1 
ATOM   5184 O O   . LEU E 5  80  ? -15.45882 -44.68759 28.49439  1.000 28.80204 ? 94  LEU E O   1 
ATOM   5185 C CB  . LEU E 5  80  ? -17.14091 -41.99053 28.44360  1.000 28.40953 ? 94  LEU E CB  1 
ATOM   5186 C CG  . LEU E 5  80  ? -17.49578 -40.53817 28.12819  1.000 26.54128 ? 94  LEU E CG  1 
ATOM   5187 C CD1 . LEU E 5  80  ? -18.96211 -40.40662 27.77101  1.000 30.17306 ? 94  LEU E CD1 1 
ATOM   5188 C CD2 . LEU E 5  80  ? -17.16239 -39.66314 29.32080  1.000 25.17449 ? 94  LEU E CD2 1 
ATOM   5189 N N   . GLU E 5  81  ? -15.26117 -43.68418 30.50357  1.000 28.64427 ? 95  GLU E N   1 
ATOM   5190 C CA  . GLU E 5  81  ? -15.22202 -44.90733 31.28548  1.000 30.22695 ? 95  GLU E CA  1 
ATOM   5191 C C   . GLU E 5  81  ? -16.40451 -44.92082 32.24418  1.000 30.61985 ? 95  GLU E C   1 
ATOM   5192 O O   . GLU E 5  81  ? -17.02122 -43.88606 32.51293  1.000 30.06797 ? 95  GLU E O   1 
ATOM   5193 C CB  . GLU E 5  81  ? -13.90494 -45.03243 32.06622  1.000 34.07077 ? 95  GLU E CB  1 
ATOM   5194 C CG  . GLU E 5  81  ? -12.65859 -44.72917 31.24228  1.000 39.47681 ? 95  GLU E CG  1 
ATOM   5195 C CD  . GLU E 5  81  ? -12.22608 -45.89411 30.36693  1.000 53.46615 ? 95  GLU E CD  1 
ATOM   5196 O OE1 . GLU E 5  81  ? -12.96718 -46.89756 30.28811  1.000 50.65327 ? 95  GLU E OE1 1 
ATOM   5197 O OE2 . GLU E 5  81  ? -11.14139 -45.80373 29.75255  1.000 56.31533 ? 95  GLU E OE2 1 
ATOM   5198 N N   . LEU E 5  82  ? -16.71835 -46.11316 32.75899  1.000 31.96110 ? 96  LEU E N   1 
ATOM   5199 C CA  . LEU E 5  82  ? -17.81784 -46.23906 33.71090  1.000 31.19067 ? 96  LEU E CA  1 
ATOM   5200 C C   . LEU E 5  82  ? -17.60452 -45.36203 34.93653  1.000 37.72802 ? 96  LEU E C   1 
ATOM   5201 O O   . LEU E 5  82  ? -18.57270 -44.84257 35.50498  1.000 33.31791 ? 96  LEU E O   1 
ATOM   5202 C CB  . LEU E 5  82  ? -17.98459 -47.69650 34.13711  1.000 39.27976 ? 96  LEU E CB  1 
ATOM   5203 C CG  . LEU E 5  82  ? -18.24363 -48.73188 33.04522  1.000 44.87735 ? 96  LEU E CG  1 
ATOM   5204 C CD1 . LEU E 5  82  ? -18.56519 -50.06746 33.68740  1.000 42.81994 ? 96  LEU E CD1 1 
ATOM   5205 C CD2 . LEU E 5  82  ? -19.36792 -48.28507 32.12703  1.000 42.26026 ? 96  LEU E CD2 1 
ATOM   5206 N N   . GLY E 5  83  ? -16.35363 -45.18459 35.35490  1.000 30.82839 ? 97  GLY E N   1 
ATOM   5207 C CA  . GLY E 5  83  ? -16.02216 -44.36502 36.50088  1.000 33.69152 ? 97  GLY E CA  1 
ATOM   5208 C C   . GLY E 5  83  ? -16.11748 -42.87424 36.28582  1.000 32.61932 ? 97  GLY E C   1 
ATOM   5209 O O   . GLY E 5  83  ? -15.89706 -42.11046 37.22941  1.000 25.67359 ? 97  GLY E O   1 
ATOM   5210 N N   . ASP E 5  84  ? -16.43083 -42.43218 35.06644  1.000 26.15246 ? 98  ASP E N   1 
ATOM   5211 C CA  . ASP E 5  84  ? -16.62532 -41.01416 34.79698  1.000 29.58725 ? 98  ASP E CA  1 
ATOM   5212 C C   . ASP E 5  84  ? -18.03659 -40.53837 35.11810  1.000 28.03555 ? 98  ASP E C   1 
ATOM   5213 O O   . ASP E 5  84  ? -18.29764 -39.33213 35.03564  1.000 21.00693 ? 98  ASP E O   1 
ATOM   5214 C CB  . ASP E 5  84  ? -16.30193 -40.70338 33.33128  1.000 27.19616 ? 98  ASP E CB  1 
ATOM   5215 C CG  . ASP E 5  84  ? -14.84695 -40.97215 32.98278  1.000 33.20752 ? 98  ASP E CG  1 
ATOM   5216 O OD1 . ASP E 5  84  ? -13.98529 -40.84893 33.87835  1.000 30.85539 ? 98  ASP E OD1 1 
ATOM   5217 O OD2 . ASP E 5  84  ? -14.56348 -41.29965 31.81084  1.000 31.27864 ? 98  ASP E OD2 1 
ATOM   5218 N N   . SER E 5  85  ? -18.94410 -41.44705 35.47322  1.000 25.82325 ? 99  SER E N   1 
ATOM   5219 C CA  . SER E 5  85  ? -20.30925 -41.06374 35.81117  1.000 29.02911 ? 99  SER E CA  1 
ATOM   5220 C C   . SER E 5  85  ? -20.30494 -40.12356 37.00791  1.000 24.74967 ? 99  SER E C   1 
ATOM   5221 O O   . SER E 5  85  ? -19.76253 -40.45538 38.06676  1.000 24.18843 ? 99  SER E O   1 
ATOM   5222 C CB  . SER E 5  85  ? -21.14610 -42.30768 36.10843  1.000 23.13906 ? 99  SER E CB  1 
ATOM   5223 O OG  . SER E 5  85  ? -21.07010 -43.24101 35.04353  1.000 23.45034 ? 99  SER E OG  1 
ATOM   5224 N N   . ALA E 5  86  ? -20.90214 -38.94823 36.83738  1.000 18.91523 ? 100 ALA E N   1 
ATOM   5225 C CA  . ALA E 5  86  ? -20.84719 -37.91765 37.86491  1.000 24.25443 ? 100 ALA E CA  1 
ATOM   5226 C C   . ALA E 5  86  ? -21.80045 -36.79465 37.48737  1.000 23.04145 ? 100 ALA E C   1 
ATOM   5227 O O   . ALA E 5  86  ? -22.36215 -36.76839 36.38907  1.000 22.86613 ? 100 ALA E O   1 
ATOM   5228 C CB  . ALA E 5  86  ? -19.42529 -37.37674 38.03999  1.000 17.32275 ? 100 ALA E CB  1 
ATOM   5229 N N   . LEU E 5  87  ? -21.97917 -35.86903 38.42495  1.000 20.11014 ? 101 LEU E N   1 
ATOM   5230 C CA  . LEU E 5  87  ? -22.64550 -34.60306 38.15756  1.000 23.33491 ? 101 LEU E CA  1 
ATOM   5231 C C   . LEU E 5  87  ? -21.58007 -33.56897 37.82088  1.000 23.64196 ? 101 LEU E C   1 
ATOM   5232 O O   . LEU E 5  87  ? -20.71424 -33.27021 38.65111  1.000 20.07357 ? 101 LEU E O   1 
ATOM   5233 C CB  . LEU E 5  87  ? -23.47443 -34.14999 39.35884  1.000 24.93490 ? 101 LEU E CB  1 
ATOM   5234 C CG  . LEU E 5  87  ? -24.26166 -32.85107 39.16142  1.000 23.40626 ? 101 LEU E CG  1 
ATOM   5235 C CD1 . LEU E 5  87  ? -25.33005 -33.02618 38.08926  1.000 26.49358 ? 101 LEU E CD1 1 
ATOM   5236 C CD2 . LEU E 5  87  ? -24.87966 -32.37600 40.47212  1.000 23.03083 ? 101 LEU E CD2 1 
ATOM   5237 N N   . TYR E 5  88  ? -21.63540 -33.03545 36.60615  1.000 24.02655 ? 102 TYR E N   1 
ATOM   5238 C CA  . TYR E 5  88  ? -20.66077 -32.06204 36.13482  1.000 20.28646 ? 102 TYR E CA  1 
ATOM   5239 C C   . TYR E 5  88  ? -21.26076 -30.66860 36.26508  1.000 22.45713 ? 102 TYR E C   1 
ATOM   5240 O O   . TYR E 5  88  ? -22.28542 -30.36523 35.64361  1.000 25.59537 ? 102 TYR E O   1 
ATOM   5241 C CB  . TYR E 5  88  ? -20.24546 -32.36845 34.69517  1.000 17.56548 ? 102 TYR E CB  1 
ATOM   5242 C CG  . TYR E 5  88  ? -19.40867 -33.62477 34.60798  1.000 19.69030 ? 102 TYR E CG  1 
ATOM   5243 C CD1 . TYR E 5  88  ? -18.02672 -33.56982 34.73589  1.000 21.83647 ? 102 TYR E CD1 1 
ATOM   5244 C CD2 . TYR E 5  88  ? -20.00191 -34.86952 34.43973  1.000 19.68129 ? 102 TYR E CD2 1 
ATOM   5245 C CE1 . TYR E 5  88  ? -17.25688 -34.71472 34.67981  1.000 22.61755 ? 102 TYR E CE1 1 
ATOM   5246 C CE2 . TYR E 5  88  ? -19.23833 -36.02310 34.38052  1.000 16.95799 ? 102 TYR E CE2 1 
ATOM   5247 C CZ  . TYR E 5  88  ? -17.86618 -35.93792 34.50230  1.000 21.96914 ? 102 TYR E CZ  1 
ATOM   5248 O OH  . TYR E 5  88  ? -17.09731 -37.07816 34.44822  1.000 24.57108 ? 102 TYR E OH  1 
ATOM   5249 N N   . LEU E 5  89  ? -20.62710 -29.83380 37.08030  1.000 17.94358 ? 103 LEU E N   1 
ATOM   5250 C CA  . LEU E 5  89  ? -21.14784 -28.52475 37.44090  1.000 20.63819 ? 103 LEU E CA  1 
ATOM   5251 C C   . LEU E 5  89  ? -20.27810 -27.42915 36.84583  1.000 21.19063 ? 103 LEU E C   1 
ATOM   5252 O O   . LEU E 5  89  ? -19.04709 -27.53255 36.84234  1.000 22.71281 ? 103 LEU E O   1 
ATOM   5253 C CB  . LEU E 5  89  ? -21.19929 -28.35747 38.96248  1.000 17.55890 ? 103 LEU E CB  1 
ATOM   5254 C CG  . LEU E 5  89  ? -22.13272 -29.28088 39.74385  1.000 21.69280 ? 103 LEU E CG  1 
ATOM   5255 C CD1 . LEU E 5  89  ? -21.69723 -29.36454 41.19912  1.000 19.60566 ? 103 LEU E CD1 1 
ATOM   5256 C CD2 . LEU E 5  89  ? -23.56112 -28.78724 39.63962  1.000 17.74661 ? 103 LEU E CD2 1 
ATOM   5257 N N   . CYS E 5  90  ? -20.92223 -26.37735 36.35342  1.000 16.85506 ? 104 CYS E N   1 
ATOM   5258 C CA  . CYS E 5  90  ? -20.22944 -25.17568 35.92327  1.000 18.68109 ? 104 CYS E CA  1 
ATOM   5259 C C   . CYS E 5  90  ? -20.64582 -24.01845 36.81905  1.000 18.66701 ? 104 CYS E C   1 
ATOM   5260 O O   . CYS E 5  90  ? -21.77379 -23.97150 37.32026  1.000 20.97392 ? 104 CYS E O   1 
ATOM   5261 C CB  . CYS E 5  90  ? -20.51470 -24.84329 34.44672  1.000 24.28540 ? 104 CYS E CB  1 
ATOM   5262 S SG  . CYS E 5  90  ? -21.98106 -23.83570 34.18775  1.000 40.15699 ? 104 CYS E SG  1 
ATOM   5263 N N   . ALA E 5  91  ? -19.71558 -23.09454 37.03440  1.000 21.54183 ? 105 ALA E N   1 
ATOM   5264 C CA  . ALA E 5  91  ? -19.95069 -21.94521 37.89213  1.000 21.50751 ? 105 ALA E CA  1 
ATOM   5265 C C   . ALA E 5  91  ? -19.38421 -20.70805 37.22000  1.000 22.42098 ? 105 ALA E C   1 
ATOM   5266 O O   . ALA E 5  91  ? -18.33770 -20.77220 36.56917  1.000 22.24563 ? 105 ALA E O   1 
ATOM   5267 C CB  . ALA E 5  91  ? -19.31265 -22.13258 39.27387  1.000 23.92776 ? 105 ALA E CB  1 
ATOM   5268 N N   . SER E 5  92  ? -20.07469 -19.58474 37.38040  1.000 20.77822 ? 106 SER E N   1 
ATOM   5269 C CA  . SER E 5  92  ? -19.65128 -18.33813 36.76919  1.000 20.92759 ? 106 SER E CA  1 
ATOM   5270 C C   . SER E 5  92  ? -19.48463 -17.25407 37.82506  1.000 19.52190 ? 106 SER E C   1 
ATOM   5271 O O   . SER E 5  92  ? -20.06178 -17.31493 38.91449  1.000 20.65760 ? 106 SER E O   1 
ATOM   5272 C CB  . SER E 5  92  ? -20.64417 -17.87976 35.69161  1.000 22.72890 ? 106 SER E CB  1 
ATOM   5273 O OG  . SER E 5  92  ? -21.77527 -17.24647 36.25661  1.000 22.87913 ? 106 SER E OG  1 
ATOM   5274 N N   . SER E 5  93  ? -18.66802 -16.26087 37.48329  1.000 19.14059 ? 107 SER E N   1 
ATOM   5275 C CA  . SER E 5  93  ? -18.44767 -15.10422 38.33495  1.000 20.51073 ? 107 SER E CA  1 
ATOM   5276 C C   . SER E 5  93  ? -18.12108 -13.91200 37.44940  1.000 22.21912 ? 107 SER E C   1 
ATOM   5277 O O   . SER E 5  93  ? -17.74255 -14.06439 36.28504  1.000 21.27370 ? 107 SER E O   1 
ATOM   5278 C CB  . SER E 5  93  ? -17.32400 -15.35142 39.34989  1.000 25.27813 ? 107 SER E CB  1 
ATOM   5279 O OG  . SER E 5  93  ? -16.12561 -15.74480 38.70138  1.000 24.90712 ? 107 SER E OG  1 
ATOM   5280 N N   . LEU E 5  94  ? -18.27481 -12.71570 38.01946  1.000 25.52740 ? 108 LEU E N   1 
ATOM   5281 C CA  . LEU E 5  94  ? -17.99313 -11.49449 37.27184  1.000 23.09326 ? 108 LEU E CA  1 
ATOM   5282 C C   . LEU E 5  94  ? -16.52339 -11.41840 36.87326  1.000 30.40464 ? 108 LEU E C   1 
ATOM   5283 O O   . LEU E 5  94  ? -16.19558 -11.19389 35.70194  1.000 26.67705 ? 108 LEU E O   1 
ATOM   5284 C CB  . LEU E 5  94  ? -18.39239 -10.27380 38.10162  1.000 29.70825 ? 108 LEU E CB  1 
ATOM   5285 C CG  . LEU E 5  94  ? -18.15747 -8.90366  37.46309  1.000 35.90407 ? 108 LEU E CG  1 
ATOM   5286 C CD1 . LEU E 5  94  ? -18.87951 -8.80172  36.12524  1.000 35.41992 ? 108 LEU E CD1 1 
ATOM   5287 C CD2 . LEU E 5  94  ? -18.60410 -7.79442  38.40486  1.000 27.02880 ? 108 LEU E CD2 1 
ATOM   5288 N N   . ARG E 5  95  ? -15.62418 -11.60898 37.83289  1.000 24.97187 ? 109 ARG E N   1 
ATOM   5289 C CA  . ARG E 5  95  ? -14.19121 -11.50260 37.60452  1.000 25.35780 ? 109 ARG E CA  1 
ATOM   5290 C C   . ARG E 5  95  ? -13.51904 -12.85868 37.78290  1.000 22.74606 ? 109 ARG E C   1 
ATOM   5291 O O   . ARG E 5  95  ? -14.09290 -13.80378 38.33014  1.000 24.87181 ? 109 ARG E O   1 
ATOM   5292 C CB  . ARG E 5  95  ? -13.57280 -10.46184 38.54450  1.000 28.11185 ? 109 ARG E CB  1 
ATOM   5293 C CG  . ARG E 5  95  ? -14.25303 -9.10454  38.46196  1.000 36.74919 ? 109 ARG E CG  1 
ATOM   5294 C CD  . ARG E 5  95  ? -13.69135 -8.12325  39.47365  1.000 41.15398 ? 109 ARG E CD  1 
ATOM   5295 N NE  . ARG E 5  95  ? -14.25008 -6.78883  39.29234  1.000 51.78555 ? 109 ARG E NE  1 
ATOM   5296 C CZ  . ARG E 5  95  ? -15.06168 -6.19289  40.15512  1.000 53.03144 ? 109 ARG E CZ  1 
ATOM   5297 N NH1 . ARG E 5  95  ? -15.42499 -6.78199  41.28264  1.000 49.70831 ? 109 ARG E NH1 1 
ATOM   5298 N NH2 . ARG E 5  95  ? -15.52074 -4.97544  39.87950  1.000 54.91342 ? 109 ARG E NH2 1 
ATOM   5299 N N   . ALA E 5  96  ? -12.28004 -12.93993 37.30653  1.000 22.37009 ? 110 ALA E N   1 
ATOM   5300 C CA  . ALA E 5  96  ? -11.54695 -14.19648 37.31756  1.000 22.77296 ? 110 ALA E CA  1 
ATOM   5301 C C   . ALA E 5  96  ? -11.07645 -14.55240 38.72416  1.000 19.56009 ? 110 ALA E C   1 
ATOM   5302 O O   . ALA E 5  96  ? -10.83457 -13.68061 39.56327  1.000 15.06612 ? 110 ALA E O   1 
ATOM   5303 C CB  . ALA E 5  96  ? -10.34531 -14.11646 36.37781  1.000 24.03635 ? 110 ALA E CB  1 
ATOM   5304 N N   . GLU E 5  97  ? -10.94554 -15.85974 38.96880  1.000 17.82992 ? 111 GLU E N   1 
ATOM   5305 C CA  . GLU E 5  97  ? -10.38182 -16.39228 40.21290  1.000 21.56982 ? 111 GLU E CA  1 
ATOM   5306 C C   . GLU E 5  97  ? -11.13564 -15.87635 41.43707  1.000 25.04982 ? 111 GLU E C   1 
ATOM   5307 O O   . GLU E 5  97  ? -10.54112 -15.50661 42.45205  1.000 23.36772 ? 111 GLU E O   1 
ATOM   5308 C CB  . GLU E 5  97  ? -8.88384  -16.08647 40.30989  1.000 22.36355 ? 111 GLU E CB  1 
ATOM   5309 C CG  . GLU E 5  97  ? -8.13285  -16.41631 39.02411  1.000 24.39348 ? 111 GLU E CG  1 
ATOM   5310 C CD  . GLU E 5  97  ? -6.62187  -16.36033 39.16693  1.000 34.32910 ? 111 GLU E CD  1 
ATOM   5311 O OE1 . GLU E 5  97  ? -6.11927  -16.35040 40.30949  1.000 30.11460 ? 111 GLU E OE1 1 
ATOM   5312 O OE2 . GLU E 5  97  ? -5.93471  -16.32552 38.12420  1.000 34.16830 ? 111 GLU E OE2 1 
ATOM   5313 N N   . SER E 5  98  ? -12.46012 -15.85786 41.33936  1.000 22.80587 ? 112 SER E N   1 
ATOM   5314 C CA  . SER E 5  98  ? -13.31168 -15.40462 42.42656  1.000 24.64282 ? 112 SER E CA  1 
ATOM   5315 C C   . SER E 5  98  ? -13.63980 -16.56281 43.35713  1.000 22.58377 ? 112 SER E C   1 
ATOM   5316 O O   . SER E 5  98  ? -13.79190 -17.70660 42.91887  1.000 19.99274 ? 112 SER E O   1 
ATOM   5317 C CB  . SER E 5  98  ? -14.60348 -14.79538 41.87795  1.000 22.64552 ? 112 SER E CB  1 
ATOM   5318 O OG  . SER E 5  98  ? -15.37493 -14.20399 42.90853  1.000 25.17706 ? 112 SER E OG  1 
ATOM   5319 N N   . GLY E 5  99  ? -13.73351 -16.26073 44.64611  1.000 22.71128 ? 113 GLY E N   1 
ATOM   5320 C CA  . GLY E 5  99  ? -14.24191 -17.21294 45.60491  1.000 25.00899 ? 113 GLY E CA  1 
ATOM   5321 C C   . GLY E 5  99  ? -15.74469 -17.20775 45.73825  1.000 25.34487 ? 113 GLY E C   1 
ATOM   5322 O O   . GLY E 5  99  ? -16.30175 -18.03645 46.46503  1.000 24.21690 ? 113 GLY E O   1 
ATOM   5323 N N   . GLU E 5  100 ? -16.42256 -16.29146 45.05007  1.000 23.16190 ? 114 GLU E N   1 
ATOM   5324 C CA  . GLU E 5  100 ? -17.87820 -16.17067 45.08130  1.000 23.37662 ? 114 GLU E CA  1 
ATOM   5325 C C   . GLU E 5  100 ? -18.41031 -16.67063 43.74250  1.000 25.04621 ? 114 GLU E C   1 
ATOM   5326 O O   . GLU E 5  100 ? -18.43303 -15.92905 42.75552  1.000 24.96992 ? 114 GLU E O   1 
ATOM   5327 C CB  . GLU E 5  100 ? -18.29573 -14.72861 45.35374  1.000 22.45161 ? 114 GLU E CB  1 
ATOM   5328 C CG  . GLU E 5  100 ? -17.94321 -14.24110 46.75130  1.000 23.64306 ? 114 GLU E CG  1 
ATOM   5329 C CD  . GLU E 5  100 ? -18.08365 -12.73847 46.89967  1.000 33.73555 ? 114 GLU E CD  1 
ATOM   5330 O OE1 . GLU E 5  100 ? -17.74070 -12.01067 45.94520  1.000 47.79217 ? 114 GLU E OE1 1 
ATOM   5331 O OE2 . GLU E 5  100 ? -18.53688 -12.28458 47.97062  1.000 39.60063 ? 114 GLU E OE2 1 
ATOM   5332 N N   . LEU E 5  101 ? -18.83566 -17.92927 43.71239  1.000 23.39492 ? 115 LEU E N   1 
ATOM   5333 C CA  . LEU E 5  101 ? -19.25695 -18.58655 42.48620  1.000 21.33221 ? 115 LEU E CA  1 
ATOM   5334 C C   . LEU E 5  101 ? -20.76290 -18.81298 42.48668  1.000 23.06384 ? 115 LEU E C   1 
ATOM   5335 O O   . LEU E 5  101 ? -21.38214 -19.00401 43.53700  1.000 19.96287 ? 115 LEU E O   1 
ATOM   5336 C CB  . LEU E 5  101 ? -18.53511 -19.92511 42.30583  1.000 16.17421 ? 115 LEU E CB  1 
ATOM   5337 C CG  . LEU E 5  101 ? -17.01213 -19.86144 42.18379  1.000 25.88773 ? 115 LEU E CG  1 
ATOM   5338 C CD1 . LEU E 5  101 ? -16.41861 -21.26173 42.20565  1.000 22.89217 ? 115 LEU E CD1 1 
ATOM   5339 C CD2 . LEU E 5  101 ? -16.60386 -19.11807 40.91783  1.000 23.93964 ? 115 LEU E CD2 1 
ATOM   5340 N N   . PHE E 5  102 ? -21.34296 -18.79109 41.28898  1.000 19.84007 ? 116 PHE E N   1 
ATOM   5341 C CA  . PHE E 5  102 ? -22.76399 -19.04739 41.07978  1.000 20.23825 ? 116 PHE E CA  1 
ATOM   5342 C C   . PHE E 5  102 ? -22.88038 -20.26033 40.16697  1.000 19.53011 ? 116 PHE E C   1 
ATOM   5343 O O   . PHE E 5  102 ? -22.56097 -20.18068 38.97531  1.000 23.29520 ? 116 PHE E O   1 
ATOM   5344 C CB  . PHE E 5  102 ? -23.46052 -17.82287 40.48760  1.000 24.69258 ? 116 PHE E CB  1 
ATOM   5345 C CG  . PHE E 5  102 ? -23.38008 -16.60437 41.36363  1.000 32.64083 ? 116 PHE E CG  1 
ATOM   5346 C CD1 . PHE E 5  102 ? -22.25186 -15.79825 41.35387  1.000 29.37060 ? 116 PHE E CD1 1 
ATOM   5347 C CD2 . PHE E 5  102 ? -24.42614 -16.27468 42.21066  1.000 35.39614 ? 116 PHE E CD2 1 
ATOM   5348 C CE1 . PHE E 5  102 ? -22.17162 -14.68197 42.16622  1.000 36.13011 ? 116 PHE E CE1 1 
ATOM   5349 C CE2 . PHE E 5  102 ? -24.35226 -15.15892 43.02648  1.000 39.11270 ? 116 PHE E CE2 1 
ATOM   5350 C CZ  . PHE E 5  102 ? -23.22390 -14.36171 43.00367  1.000 40.56462 ? 116 PHE E CZ  1 
ATOM   5351 N N   . PHE E 5  103 ? -23.32835 -21.37799 40.72847  1.000 14.63700 ? 117 PHE E N   1 
ATOM   5352 C CA  . PHE E 5  103 ? -23.30530 -22.65836 40.04069  1.000 17.36244 ? 117 PHE E CA  1 
ATOM   5353 C C   . PHE E 5  103 ? -24.57109 -22.86997 39.22076  1.000 23.16776 ? 117 PHE E C   1 
ATOM   5354 O O   . PHE E 5  103 ? -25.66372 -22.43894 39.59993  1.000 23.94561 ? 117 PHE E O   1 
ATOM   5355 C CB  . PHE E 5  103 ? -23.15495 -23.80426 41.04483  1.000 19.45293 ? 117 PHE E CB  1 
ATOM   5356 C CG  . PHE E 5  103 ? -21.74155 -24.03320 41.50671  1.000 22.00140 ? 117 PHE E CG  1 
ATOM   5357 C CD1 . PHE E 5  103 ? -21.21620 -23.30428 42.56078  1.000 23.18226 ? 117 PHE E CD1 1 
ATOM   5358 C CD2 . PHE E 5  103 ? -20.94374 -24.98629 40.89510  1.000 19.32157 ? 117 PHE E CD2 1 
ATOM   5359 C CE1 . PHE E 5  103 ? -19.91610 -23.51605 42.99234  1.000 23.15213 ? 117 PHE E CE1 1 
ATOM   5360 C CE2 . PHE E 5  103 ? -19.64295 -25.20262 41.32068  1.000 18.71796 ? 117 PHE E CE2 1 
ATOM   5361 C CZ  . PHE E 5  103 ? -19.12983 -24.46656 42.36945  1.000 21.28155 ? 117 PHE E CZ  1 
ATOM   5362 N N   . GLY E 5  104 ? -24.40865 -23.54301 38.08305  1.000 24.64930 ? 118 GLY E N   1 
ATOM   5363 C CA  . GLY E 5  104 ? -25.53471 -24.08296 37.35676  1.000 22.69776 ? 118 GLY E CA  1 
ATOM   5364 C C   . GLY E 5  104 ? -26.07337 -25.32445 38.04025  1.000 26.84267 ? 118 GLY E C   1 
ATOM   5365 O O   . GLY E 5  104 ? -25.56782 -25.77985 39.06530  1.000 23.92551 ? 118 GLY E O   1 
ATOM   5366 N N   . GLU E 5  105 ? -27.12428 -25.88863 37.44881  1.000 24.74314 ? 119 GLU E N   1 
ATOM   5367 C CA  . GLU E 5  105 ? -27.77351 -27.04590 38.05039  1.000 29.31013 ? 119 GLU E CA  1 
ATOM   5368 C C   . GLU E 5  105 ? -27.08098 -28.36145 37.71863  1.000 23.05275 ? 119 GLU E C   1 
ATOM   5369 O O   . GLU E 5  105 ? -27.41819 -29.38597 38.32130  1.000 27.41035 ? 119 GLU E O   1 
ATOM   5370 C CB  . GLU E 5  105 ? -29.24362 -27.09983 37.62754  1.000 26.13876 ? 119 GLU E CB  1 
ATOM   5371 C CG  . GLU E 5  105 ? -30.10096 -26.05208 38.32544  1.000 32.69962 ? 119 GLU E CG  1 
ATOM   5372 C CD  . GLU E 5  105 ? -31.58386 -26.22648 38.05930  1.000 50.32878 ? 119 GLU E CD  1 
ATOM   5373 O OE1 . GLU E 5  105 ? -31.93971 -26.90222 37.07100  1.000 48.12255 ? 119 GLU E OE1 1 
ATOM   5374 O OE2 . GLU E 5  105 ? -32.39454 -25.68679 38.84162  1.000 57.65296 ? 119 GLU E OE2 1 
ATOM   5375 N N   . GLY E 5  106 ? -26.13590 -28.36294 36.79411  1.000 19.30123 ? 120 GLY E N   1 
ATOM   5376 C CA  . GLY E 5  106 ? -25.31437 -29.53511 36.57285  1.000 20.90527 ? 120 GLY E CA  1 
ATOM   5377 C C   . GLY E 5  106 ? -25.79896 -30.38840 35.41549  1.000 26.26506 ? 120 GLY E C   1 
ATOM   5378 O O   . GLY E 5  106 ? -26.98944 -30.42825 35.08535  1.000 21.68482 ? 120 GLY E O   1 
ATOM   5379 N N   . SER E 5  107 ? -24.85347 -31.07970 34.77939  1.000 20.54340 ? 121 SER E N   1 
ATOM   5380 C CA  . SER E 5  107 ? -25.14606 -32.09885 33.77760  1.000 21.07119 ? 121 SER E CA  1 
ATOM   5381 C C   . SER E 5  107 ? -24.91333 -33.46216 34.42017  1.000 23.05616 ? 121 SER E C   1 
ATOM   5382 O O   . SER E 5  107 ? -23.77651 -33.81219 34.75431  1.000 24.61105 ? 121 SER E O   1 
ATOM   5383 C CB  . SER E 5  107 ? -24.27300 -31.92057 32.53603  1.000 19.59009 ? 121 SER E CB  1 
ATOM   5384 O OG  . SER E 5  107 ? -24.65140 -30.77245 31.79441  1.000 21.23106 ? 121 SER E OG  1 
ATOM   5385 N N   . ARG E 5  108 ? -25.98694 -34.22672 34.59735  1.000 22.86590 ? 122 ARG E N   1 
ATOM   5386 C CA  . ARG E 5  108 ? -25.91087 -35.54138 35.22614  1.000 22.02471 ? 122 ARG E CA  1 
ATOM   5387 C C   . ARG E 5  108 ? -25.58167 -36.57426 34.15547  1.000 28.42833 ? 122 ARG E C   1 
ATOM   5388 O O   . ARG E 5  108 ? -26.42992 -36.90768 33.32160  1.000 23.67340 ? 122 ARG E O   1 
ATOM   5389 C CB  . ARG E 5  108 ? -27.21952 -35.87745 35.93523  1.000 27.45210 ? 122 ARG E CB  1 
ATOM   5390 C CG  . ARG E 5  108 ? -27.16420 -37.14515 36.76779  1.000 30.02378 ? 122 ARG E CG  1 
ATOM   5391 C CD  . ARG E 5  108 ? -28.29479 -37.18029 37.78076  1.000 33.83445 ? 122 ARG E CD  1 
ATOM   5392 N NE  . ARG E 5  108 ? -28.08500 -36.22182 38.85894  1.000 37.30981 ? 122 ARG E NE  1 
ATOM   5393 C CZ  . ARG E 5  108 ? -27.35583 -36.46026 39.94071  1.000 36.65359 ? 122 ARG E CZ  1 
ATOM   5394 N NH1 . ARG E 5  108 ? -26.75291 -37.62341 40.12541  1.000 35.34393 ? 122 ARG E NH1 1 
ATOM   5395 N NH2 . ARG E 5  108 ? -27.22977 -35.50846 40.86090  1.000 32.88917 ? 122 ARG E NH2 1 
ATOM   5396 N N   . LEU E 5  109 ? -24.35313 -37.08181 34.18082  1.000 27.29209 ? 123 LEU E N   1 
ATOM   5397 C CA  . LEU E 5  109 ? -23.86301 -38.01685 33.17846  1.000 25.67504 ? 123 LEU E CA  1 
ATOM   5398 C C   . LEU E 5  109 ? -23.71963 -39.40446 33.78623  1.000 26.54234 ? 123 LEU E C   1 
ATOM   5399 O O   . LEU E 5  109 ? -23.04128 -39.57482 34.80456  1.000 26.15181 ? 123 LEU E O   1 
ATOM   5400 C CB  . LEU E 5  109 ? -22.51928 -37.55413 32.61118  1.000 24.17173 ? 123 LEU E CB  1 
ATOM   5401 C CG  . LEU E 5  109 ? -21.77199 -38.57568 31.75075  1.000 27.90918 ? 123 LEU E CG  1 
ATOM   5402 C CD1 . LEU E 5  109 ? -22.51679 -38.82888 30.44636  1.000 25.75723 ? 123 LEU E CD1 1 
ATOM   5403 C CD2 . LEU E 5  109 ? -20.34458 -38.12006 31.48191  1.000 24.97291 ? 123 LEU E CD2 1 
ATOM   5404 N N   . THR E 5  110 ? -24.35481 -40.38954 33.15720  1.000 24.13215 ? 124 THR E N   1 
ATOM   5405 C CA  . THR E 5  110 ? -24.19237 -41.79447 33.50897  1.000 25.42145 ? 124 THR E CA  1 
ATOM   5406 C C   . THR E 5  110 ? -23.55980 -42.51303 32.32550  1.000 25.55689 ? 124 THR E C   1 
ATOM   5407 O O   . THR E 5  110 ? -24.13263 -42.53228 31.23079  1.000 25.63598 ? 124 THR E O   1 
ATOM   5408 C CB  . THR E 5  110 ? -25.53339 -42.43701 33.87135  1.000 27.74866 ? 124 THR E CB  1 
ATOM   5409 O OG1 . THR E 5  110 ? -26.09860 -41.76794 35.00558  1.000 31.01807 ? 124 THR E OG1 1 
ATOM   5410 C CG2 . THR E 5  110 ? -25.34388 -43.90812 34.20106  1.000 25.07872 ? 124 THR E CG2 1 
ATOM   5411 N N   . VAL E 5  111 ? -22.37997 -43.09084 32.53983  1.000 26.95004 ? 125 VAL E N   1 
ATOM   5412 C CA  . VAL E 5  111 ? -21.68142 -43.86141 31.51625  1.000 25.82995 ? 125 VAL E CA  1 
ATOM   5413 C C   . VAL E 5  111 ? -21.98240 -45.33458 31.74273  1.000 32.33829 ? 125 VAL E C   1 
ATOM   5414 O O   . VAL E 5  111 ? -21.80696 -45.84779 32.85526  1.000 30.89490 ? 125 VAL E O   1 
ATOM   5415 C CB  . VAL E 5  111 ? -20.16713 -43.59566 31.54545  1.000 26.23221 ? 125 VAL E CB  1 
ATOM   5416 C CG1 . VAL E 5  111 ? -19.48519 -44.31939 30.39342  1.000 28.86710 ? 125 VAL E CG1 1 
ATOM   5417 C CG2 . VAL E 5  111 ? -19.89035 -42.10267 31.48178  1.000 24.15480 ? 125 VAL E CG2 1 
ATOM   5418 N N   . LEU E 5  112 ? -22.42435 -46.01907 30.69135  1.000 29.82155 ? 126 LEU E N   1 
ATOM   5419 C CA  . LEU E 5  112 ? -22.96651 -47.36084 30.82210  1.000 32.71858 ? 126 LEU E CA  1 
ATOM   5420 C C   . LEU E 5  112 ? -22.20571 -48.37640 29.98015  1.000 41.55827 ? 126 LEU E C   1 
ATOM   5421 O O   . LEU E 5  112 ? -21.50996 -48.04359 29.01678  1.000 33.71472 ? 126 LEU E O   1 
ATOM   5422 C CB  . LEU E 5  112 ? -24.44983 -47.40110 30.43566  1.000 36.12747 ? 126 LEU E CB  1 
ATOM   5423 C CG  . LEU E 5  112 ? -25.39887 -46.79653 31.46364  1.000 29.98783 ? 126 LEU E CG  1 
ATOM   5424 C CD1 . LEU E 5  112 ? -26.83619 -47.16982 31.13863  1.000 33.64041 ? 126 LEU E CD1 1 
ATOM   5425 C CD2 . LEU E 5  112 ? -25.00834 -47.26200 32.85770  1.000 34.47024 ? 126 LEU E CD2 1 
ATOM   5426 N N   . GLU E 5  113 ? -22.36310 -49.63638 30.38659  1.000 43.91988 ? 127 GLU E N   1 
ATOM   5427 C CA  . GLU E 5  113 ? -21.86992 -50.77260 29.61819  1.000 48.27453 ? 127 GLU E CA  1 
ATOM   5428 C C   . GLU E 5  113 ? -22.60043 -50.90651 28.29451  1.000 53.17503 ? 127 GLU E C   1 
ATOM   5429 O O   . GLU E 5  113 ? -21.98849 -51.17555 27.25381  1.000 45.70023 ? 127 GLU E O   1 
ATOM   5430 C CB  . GLU E 5  113 ? -22.08247 -52.05175 30.42544  1.000 63.89890 ? 127 GLU E CB  1 
ATOM   5431 C CG  . GLU E 5  113 ? -21.09801 -53.16051 30.18778  1.000 67.41543 ? 127 GLU E CG  1 
ATOM   5432 C CD  . GLU E 5  113 ? -19.79577 -52.92381 30.89901  1.000 81.56600 ? 127 GLU E CD  1 
ATOM   5433 O OE1 . GLU E 5  113 ? -19.51828 -51.76736 31.27692  1.000 84.55020 ? 127 GLU E OE1 1 
ATOM   5434 O OE2 . GLU E 5  113 ? -19.03199 -53.89340 31.07642  1.000 92.53563 ? 127 GLU E OE2 1 
ATOM   5435 N N   . ASP E 5  114 ? -23.91178 -50.71359 28.32669  1.000 46.27307 ? 128 ASP E N   1 
ATOM   5436 C CA  . ASP E 5  114 ? -24.82219 -51.33202 27.38295  1.000 50.45482 ? 128 ASP E CA  1 
ATOM   5437 C C   . ASP E 5  114 ? -26.20441 -50.75313 27.63474  1.000 50.07600 ? 128 ASP E C   1 
ATOM   5438 O O   . ASP E 5  114 ? -26.63297 -50.65153 28.78900  1.000 46.73275 ? 128 ASP E O   1 
ATOM   5439 C CB  . ASP E 5  114 ? -24.78340 -52.85326 27.57253  1.000 54.92054 ? 128 ASP E CB  1 
ATOM   5440 C CG  . ASP E 5  114 ? -25.99661 -53.55004 27.01619  1.000 66.62140 ? 128 ASP E CG  1 
ATOM   5441 O OD1 . ASP E 5  114 ? -26.40569 -53.23631 25.87907  1.000 63.87894 ? 128 ASP E OD1 1 
ATOM   5442 O OD2 . ASP E 5  114 ? -26.54373 -54.41992 27.72882  1.000 64.78345 ? 128 ASP E OD2 1 
ATOM   5443 N N   . LEU E 5  115 ? -26.89708 -50.34054 26.57969  1.000 40.43611 ? 129 LEU E N   1 
ATOM   5444 C CA  . LEU E 5  115 ? -28.17761 -49.67528 26.76235  1.000 39.35922 ? 129 LEU E CA  1 
ATOM   5445 C C   . LEU E 5  115 ? -29.29802 -50.63785 27.13358  1.000 44.25742 ? 129 LEU E C   1 
ATOM   5446 O O   . LEU E 5  115 ? -30.41934 -50.18544 27.39020  1.000 42.64790 ? 129 LEU E O   1 
ATOM   5447 C CB  . LEU E 5  115 ? -28.54002 -48.89526 25.49779  1.000 41.46389 ? 129 LEU E CB  1 
ATOM   5448 C CG  . LEU E 5  115 ? -27.51564 -47.81400 25.13991  1.000 40.99404 ? 129 LEU E CG  1 
ATOM   5449 C CD1 . LEU E 5  115 ? -27.95807 -47.01953 23.92228  1.000 41.02712 ? 129 LEU E CD1 1 
ATOM   5450 C CD2 . LEU E 5  115 ? -27.25057 -46.89134 26.32582  1.000 40.88329 ? 129 LEU E CD2 1 
ATOM   5451 N N   . ASN E 5  116 ? -29.02336 -51.94412 27.18554  1.000 44.20739 ? 130 ASN E N   1 
ATOM   5452 C CA  . ASN E 5  116 ? -30.03927 -52.91002 27.58531  1.000 51.11426 ? 130 ASN E CA  1 
ATOM   5453 C C   . ASN E 5  116 ? -30.31319 -52.88905 29.08238  1.000 42.40572 ? 130 ASN E C   1 
ATOM   5454 O O   . ASN E 5  116 ? -31.25719 -53.54932 29.52897  1.000 44.61836 ? 130 ASN E O   1 
ATOM   5455 C CB  . ASN E 5  116 ? -29.63252 -54.32377 27.16125  1.000 53.21529 ? 130 ASN E CB  1 
ATOM   5456 C CG  . ASN E 5  116 ? -29.22976 -54.40308 25.70064  1.000 71.72218 ? 130 ASN E CG  1 
ATOM   5457 O OD1 . ASN E 5  116 ? -29.95272 -53.94006 24.82076  1.000 71.38187 ? 130 ASN E OD1 1 
ATOM   5458 N ND2 . ASN E 5  116 ? -28.08114 -55.01381 25.43391  1.000 72.77161 ? 130 ASN E ND2 1 
ATOM   5459 N N   . LYS E 5  117 ? -29.51467 -52.16366 29.86157  1.000 37.96399 ? 131 LYS E N   1 
ATOM   5460 C CA  . LYS E 5  117 ? -29.73916 -52.01692 31.29236  1.000 42.06997 ? 131 LYS E CA  1 
ATOM   5461 C C   . LYS E 5  117 ? -30.63945 -50.83554 31.62928  1.000 35.02848 ? 131 LYS E C   1 
ATOM   5462 O O   . LYS E 5  117 ? -30.95023 -50.62826 32.80673  1.000 37.95998 ? 131 LYS E O   1 
ATOM   5463 C CB  . LYS E 5  117 ? -28.39944 -51.86786 32.02268  1.000 43.94427 ? 131 LYS E CB  1 
ATOM   5464 N N   . VAL E 5  118 ? -31.06607 -50.06559 30.63254  1.000 29.50722 ? 132 VAL E N   1 
ATOM   5465 C CA  . VAL E 5  118 ? -31.87055 -48.87052 30.85489  1.000 33.11343 ? 132 VAL E CA  1 
ATOM   5466 C C   . VAL E 5  118 ? -33.33553 -49.27226 30.96171  1.000 35.08540 ? 132 VAL E C   1 
ATOM   5467 O O   . VAL E 5  118 ? -33.87517 -49.93758 30.06972  1.000 34.25388 ? 132 VAL E O   1 
ATOM   5468 C CB  . VAL E 5  118 ? -31.65526 -47.84691 29.72741  1.000 29.31575 ? 132 VAL E CB  1 
ATOM   5469 C CG1 . VAL E 5  118 ? -32.53187 -46.62173 29.94208  1.000 25.26955 ? 132 VAL E CG1 1 
ATOM   5470 C CG2 . VAL E 5  118 ? -30.19054 -47.44726 29.65262  1.000 29.15410 ? 132 VAL E CG2 1 
ATOM   5471 N N   . PHE E 5  119 ? -33.97991 -48.87062 32.05846  1.000 31.00832 ? 133 PHE E N   1 
ATOM   5472 C CA  . PHE E 5  119 ? -35.37595 -49.18357 32.31949  1.000 28.51780 ? 133 PHE E CA  1 
ATOM   5473 C C   . PHE E 5  119 ? -36.09458 -47.94006 32.82257  1.000 25.43116 ? 133 PHE E C   1 
ATOM   5474 O O   . PHE E 5  119 ? -35.52934 -47.17665 33.61904  1.000 28.77941 ? 133 PHE E O   1 
ATOM   5475 C CB  . PHE E 5  119 ? -35.52330 -50.30491 33.35705  1.000 28.87815 ? 133 PHE E CB  1 
ATOM   5476 C CG  . PHE E 5  119 ? -35.12007 -51.65797 32.85200  1.000 36.01076 ? 133 PHE E CG  1 
ATOM   5477 C CD1 . PHE E 5  119 ? -36.01414 -52.44092 32.13980  1.000 37.96128 ? 133 PHE E CD1 1 
ATOM   5478 C CD2 . PHE E 5  119 ? -33.84807 -52.15049 33.09356  1.000 35.36261 ? 133 PHE E CD2 1 
ATOM   5479 C CE1 . PHE E 5  119 ? -35.64588 -53.68971 31.67602  1.000 39.91604 ? 133 PHE E CE1 1 
ATOM   5480 C CE2 . PHE E 5  119 ? -33.47339 -53.39807 32.63213  1.000 32.37916 ? 133 PHE E CE2 1 
ATOM   5481 C CZ  . PHE E 5  119 ? -34.37275 -54.16820 31.92211  1.000 36.24930 ? 133 PHE E CZ  1 
ATOM   5482 N N   . PRO E 5  120 ? -37.32547 -47.70775 32.37881  1.000 27.45894 ? 134 PRO E N   1 
ATOM   5483 C CA  . PRO E 5  120 ? -38.13485 -46.64123 32.96405  1.000 28.38153 ? 134 PRO E CA  1 
ATOM   5484 C C   . PRO E 5  120 ? -38.72527 -47.09358 34.28625  1.000 24.31734 ? 134 PRO E C   1 
ATOM   5485 O O   . PRO E 5  120 ? -38.79791 -48.30120 34.55957  1.000 24.03452 ? 134 PRO E O   1 
ATOM   5486 C CB  . PRO E 5  120 ? -39.22800 -46.41605 31.91035  1.000 30.61314 ? 134 PRO E CB  1 
ATOM   5487 C CG  . PRO E 5  120 ? -39.40674 -47.76288 31.29585  1.000 29.65303 ? 134 PRO E CG  1 
ATOM   5488 C CD  . PRO E 5  120 ? -38.03793 -48.41246 31.29733  1.000 28.46412 ? 134 PRO E CD  1 
ATOM   5489 N N   . PRO E 5  121 ? -39.15143 -46.16593 35.13656  1.000 24.07645 ? 135 PRO E N   1 
ATOM   5490 C CA  . PRO E 5  121 ? -39.74094 -46.56244 36.41678  1.000 27.46522 ? 135 PRO E CA  1 
ATOM   5491 C C   . PRO E 5  121 ? -41.17233 -47.04820 36.26713  1.000 29.43480 ? 135 PRO E C   1 
ATOM   5492 O O   . PRO E 5  121 ? -41.93591 -46.58104 35.41879  1.000 25.60960 ? 135 PRO E O   1 
ATOM   5493 C CB  . PRO E 5  121 ? -39.69062 -45.26958 37.23864  1.000 23.19709 ? 135 PRO E CB  1 
ATOM   5494 C CG  . PRO E 5  121 ? -39.80979 -44.19460 36.21249  1.000 23.62957 ? 135 PRO E CG  1 
ATOM   5495 C CD  . PRO E 5  121 ? -39.04743 -44.70110 35.00993  1.000 24.51013 ? 135 PRO E CD  1 
ATOM   5496 N N   . GLU E 5  122 ? -41.52318 -48.01502 37.10789  1.000 30.03826 ? 136 GLU E N   1 
ATOM   5497 C CA  . GLU E 5  122 ? -42.91570 -48.36164 37.34209  1.000 27.95154 ? 136 GLU E CA  1 
ATOM   5498 C C   . GLU E 5  122 ? -43.39389 -47.56971 38.55066  1.000 23.41341 ? 136 GLU E C   1 
ATOM   5499 O O   . GLU E 5  122 ? -42.71616 -47.53637 39.58224  1.000 28.02380 ? 136 GLU E O   1 
ATOM   5500 C CB  . GLU E 5  122 ? -43.07910 -49.86397 37.57325  1.000 25.83344 ? 136 GLU E CB  1 
ATOM   5501 C CG  . GLU E 5  122 ? -43.00753 -50.69227 36.29904  1.000 30.24164 ? 136 GLU E CG  1 
ATOM   5502 C CD  . GLU E 5  122 ? -42.92474 -52.18210 36.57200  1.000 42.61671 ? 136 GLU E CD  1 
ATOM   5503 O OE1 . GLU E 5  122 ? -42.95133 -52.57458 37.75805  1.000 33.77702 ? 136 GLU E OE1 1 
ATOM   5504 O OE2 . GLU E 5  122 ? -42.84049 -52.96141 35.59843  1.000 46.14284 ? 136 GLU E OE2 1 
ATOM   5505 N N   . VAL E 5  123 ? -44.54211 -46.91275 38.41394  1.000 26.13107 ? 137 VAL E N   1 
ATOM   5506 C CA  . VAL E 5  123 ? -45.04012 -45.98041 39.41761  1.000 23.08592 ? 137 VAL E CA  1 
ATOM   5507 C C   . VAL E 5  123 ? -46.39241 -46.46875 39.91342  1.000 29.80154 ? 137 VAL E C   1 
ATOM   5508 O O   . VAL E 5  123 ? -47.27037 -46.80622 39.11026  1.000 23.81970 ? 137 VAL E O   1 
ATOM   5509 C CB  . VAL E 5  123 ? -45.14546 -44.55007 38.85845  1.000 24.01737 ? 137 VAL E CB  1 
ATOM   5510 C CG1 . VAL E 5  123 ? -45.59021 -43.58597 39.94690  1.000 24.17852 ? 137 VAL E CG1 1 
ATOM   5511 C CG2 . VAL E 5  123 ? -43.81252 -44.11649 38.27192  1.000 21.42768 ? 137 VAL E CG2 1 
ATOM   5512 N N   . ALA E 5  124 ? -46.55452 -46.50514 41.23490  1.000 24.21921 ? 138 ALA E N   1 
ATOM   5513 C CA  . ALA E 5  124 ? -47.80524 -46.89616 41.86603  1.000 27.24566 ? 138 ALA E CA  1 
ATOM   5514 C C   . ALA E 5  124 ? -48.06660 -45.98930 43.05750  1.000 31.13050 ? 138 ALA E C   1 
ATOM   5515 O O   . ALA E 5  124 ? -47.13566 -45.60765 43.77296  1.000 27.33315 ? 138 ALA E O   1 
ATOM   5516 C CB  . ALA E 5  124 ? -47.77467 -48.36080 42.32002  1.000 18.11148 ? 138 ALA E CB  1 
ATOM   5517 N N   . VAL E 5  125 ? -49.33425 -45.64341 43.26169  1.000 27.75629 ? 139 VAL E N   1 
ATOM   5518 C CA  . VAL E 5  125 ? -49.76796 -44.84888 44.40428  1.000 26.34772 ? 139 VAL E CA  1 
ATOM   5519 C C   . VAL E 5  125 ? -50.53976 -45.75887 45.34672  1.000 28.78157 ? 139 VAL E C   1 
ATOM   5520 O O   . VAL E 5  125 ? -51.40041 -46.53235 44.90899  1.000 28.00649 ? 139 VAL E O   1 
ATOM   5521 C CB  . VAL E 5  125 ? -50.62342 -43.64563 43.97153  1.000 28.29194 ? 139 VAL E CB  1 
ATOM   5522 C CG1 . VAL E 5  125 ? -51.27973 -42.99480 45.18080  1.000 29.12402 ? 139 VAL E CG1 1 
ATOM   5523 C CG2 . VAL E 5  125 ? -49.76959 -42.63462 43.23192  1.000 34.06362 ? 139 VAL E CG2 1 
ATOM   5524 N N   . PHE E 5  126 ? -50.22214 -45.67476 46.63378  1.000 23.41755 ? 140 PHE E N   1 
ATOM   5525 C CA  . PHE E 5  126 ? -50.87369 -46.46273 47.66797  1.000 25.39365 ? 140 PHE E CA  1 
ATOM   5526 C C   . PHE E 5  126 ? -51.68507 -45.52530 48.55099  1.000 25.79453 ? 140 PHE E C   1 
ATOM   5527 O O   . PHE E 5  126 ? -51.15807 -44.52810 49.05447  1.000 25.96046 ? 140 PHE E O   1 
ATOM   5528 C CB  . PHE E 5  126 ? -49.84225 -47.24439 48.48708  1.000 25.19905 ? 140 PHE E CB  1 
ATOM   5529 C CG  . PHE E 5  126 ? -49.02524 -48.21181 47.66653  1.000 25.12889 ? 140 PHE E CG  1 
ATOM   5530 C CD1 . PHE E 5  126 ? -47.99554 -47.76015 46.85252  1.000 25.10844 ? 140 PHE E CD1 1 
ATOM   5531 C CD2 . PHE E 5  126 ? -49.29459 -49.57031 47.70163  1.000 22.77774 ? 140 PHE E CD2 1 
ATOM   5532 C CE1 . PHE E 5  126 ? -47.24889 -48.64496 46.09245  1.000 26.72919 ? 140 PHE E CE1 1 
ATOM   5533 C CE2 . PHE E 5  126 ? -48.55126 -50.46038 46.94629  1.000 27.79512 ? 140 PHE E CE2 1 
ATOM   5534 C CZ  . PHE E 5  126 ? -47.52638 -49.99694 46.14020  1.000 26.65501 ? 140 PHE E CZ  1 
ATOM   5535 N N   . GLU E 5  127 ? -52.95878 -45.84034 48.72436  1.000 22.36073 ? 141 GLU E N   1 
ATOM   5536 C CA  . GLU E 5  127 ? -53.91438 -44.94697 49.35768  1.000 27.76690 ? 141 GLU E CA  1 
ATOM   5537 C C   . GLU E 5  127 ? -53.87699 -45.08974 50.87420  1.000 24.27858 ? 141 GLU E C   1 
ATOM   5538 O O   . GLU E 5  127 ? -53.43372 -46.11421 51.40208  1.000 22.91169 ? 141 GLU E O   1 
ATOM   5539 C CB  . GLU E 5  127 ? -55.31510 -45.23310 48.82156  1.000 22.02546 ? 141 GLU E CB  1 
ATOM   5540 C CG  . GLU E 5  127 ? -55.53861 -44.66300 47.42818  1.000 28.55650 ? 141 GLU E CG  1 
ATOM   5541 C CD  . GLU E 5  127 ? -56.93827 -44.91191 46.90359  1.000 35.67359 ? 141 GLU E CD  1 
ATOM   5542 O OE1 . GLU E 5  127 ? -57.81871 -45.29261 47.70454  1.000 26.70643 ? 141 GLU E OE1 1 
ATOM   5543 O OE2 . GLU E 5  127 ? -57.15505 -44.72684 45.68665  1.000 35.92413 ? 141 GLU E OE2 1 
ATOM   5544 N N   . PRO E 5  128 ? -54.33111 -44.06768 51.60685  1.000 29.61519 ? 142 PRO E N   1 
ATOM   5545 C CA  . PRO E 5  128 ? -54.21715 -44.10297 53.06995  1.000 28.96464 ? 142 PRO E CA  1 
ATOM   5546 C C   . PRO E 5  128 ? -55.03343 -45.23058 53.67957  1.000 31.80936 ? 142 PRO E C   1 
ATOM   5547 O O   . PRO E 5  128 ? -56.09563 -45.60561 53.17823  1.000 28.61942 ? 142 PRO E O   1 
ATOM   5548 C CB  . PRO E 5  128 ? -54.75883 -42.73465 53.50592  1.000 29.59197 ? 142 PRO E CB  1 
ATOM   5549 C CG  . PRO E 5  128 ? -54.71086 -41.88256 52.28667  1.000 30.32533 ? 142 PRO E CG  1 
ATOM   5550 C CD  . PRO E 5  128 ? -54.92230 -42.80365 51.13523  1.000 27.67402 ? 142 PRO E CD  1 
ATOM   5551 N N   . SER E 5  129 ? -54.51934 -45.76934 54.77966  1.000 25.23132 ? 143 SER E N   1 
ATOM   5552 C CA  . SER E 5  129 ? -55.24645 -46.77170 55.53824  1.000 29.92066 ? 143 SER E CA  1 
ATOM   5553 C C   . SER E 5  129 ? -56.32500 -46.10758 56.38277  1.000 29.15608 ? 143 SER E C   1 
ATOM   5554 O O   . SER E 5  129 ? -56.16244 -44.98188 56.86331  1.000 26.93607 ? 143 SER E O   1 
ATOM   5555 C CB  . SER E 5  129 ? -54.29591 -47.56472 56.43518  1.000 36.16094 ? 143 SER E CB  1 
ATOM   5556 O OG  . SER E 5  129 ? -54.26254 -47.02917 57.74719  1.000 33.34380 ? 143 SER E OG  1 
ATOM   5557 N N   . GLU E 5  130 ? -57.44366 -46.81602 56.55327  1.000 34.76237 ? 144 GLU E N   1 
ATOM   5558 C CA  . GLU E 5  130 ? -58.51586 -46.29224 57.39188  1.000 33.71159 ? 144 GLU E CA  1 
ATOM   5559 C C   . GLU E 5  130 ? -58.07598 -46.17587 58.84339  1.000 28.78855 ? 144 GLU E C   1 
ATOM   5560 O O   . GLU E 5  130 ? -58.58772 -45.32563 59.58080  1.000 29.48128 ? 144 GLU E O   1 
ATOM   5561 C CB  . GLU E 5  130 ? -59.75729 -47.17863 57.28239  1.000 37.72770 ? 144 GLU E CB  1 
ATOM   5562 C CG  . GLU E 5  130 ? -60.51701 -47.03920 55.96920  1.000 51.61350 ? 144 GLU E CG  1 
ATOM   5563 C CD  . GLU E 5  130 ? -61.00271 -45.62276 55.70701  1.000 55.40244 ? 144 GLU E CD  1 
ATOM   5564 O OE1 . GLU E 5  130 ? -61.25968 -44.88147 56.68117  1.000 47.31587 ? 144 GLU E OE1 1 
ATOM   5565 O OE2 . GLU E 5  130 ? -61.12811 -45.25098 54.52020  1.000 52.59563 ? 144 GLU E OE2 1 
ATOM   5566 N N   . ALA E 5  131 ? -57.12808 -47.01461 59.26902  1.000 29.68071 ? 145 ALA E N   1 
ATOM   5567 C CA  . ALA E 5  131 ? -56.63486 -46.93549 60.63949  1.000 30.82499 ? 145 ALA E CA  1 
ATOM   5568 C C   . ALA E 5  131 ? -55.96561 -45.59395 60.90638  1.000 30.87880 ? 145 ALA E C   1 
ATOM   5569 O O   . ALA E 5  131 ? -56.17790 -44.98844 61.96277  1.000 26.83837 ? 145 ALA E O   1 
ATOM   5570 C CB  . ALA E 5  131 ? -55.67011 -48.08650 60.91948  1.000 23.18937 ? 145 ALA E CB  1 
ATOM   5571 N N   . GLU E 5  132 ? -55.16036 -45.10679 59.95663  1.000 30.72802 ? 146 GLU E N   1 
ATOM   5572 C CA  . GLU E 5  132 ? -54.52414 -43.80437 60.13385  1.000 31.50114 ? 146 GLU E CA  1 
ATOM   5573 C C   . GLU E 5  132 ? -55.55516 -42.68522 60.15006  1.000 27.03095 ? 146 GLU E C   1 
ATOM   5574 O O   . GLU E 5  132 ? -55.45079 -41.74897 60.95161  1.000 27.66353 ? 146 GLU E O   1 
ATOM   5575 C CB  . GLU E 5  132 ? -53.49398 -43.55288 59.03164  1.000 20.48520 ? 146 GLU E CB  1 
ATOM   5576 C CG  . GLU E 5  132 ? -52.74741 -42.23127 59.19881  1.000 21.92745 ? 146 GLU E CG  1 
ATOM   5577 C CD  . GLU E 5  132 ? -52.18487 -41.68387 57.89634  1.000 30.31059 ? 146 GLU E CD  1 
ATOM   5578 O OE1 . GLU E 5  132 ? -52.37490 -42.32068 56.83755  1.000 26.95363 ? 146 GLU E OE1 1 
ATOM   5579 O OE2 . GLU E 5  132 ? -51.55205 -40.60650 57.93422  1.000 26.14082 ? 146 GLU E OE2 1 
ATOM   5580 N N   . ILE E 5  133 ? -56.55368 -42.76543 59.26834  1.000 27.64509 ? 147 ILE E N   1 
ATOM   5581 C CA  . ILE E 5  133 ? -57.56825 -41.71833 59.18163  1.000 30.30503 ? 147 ILE E CA  1 
ATOM   5582 C C   . ILE E 5  133 ? -58.32307 -41.59983 60.49972  1.000 27.31468 ? 147 ILE E C   1 
ATOM   5583 O O   . ILE E 5  133 ? -58.52366 -40.49853 61.02530  1.000 29.74922 ? 147 ILE E O   1 
ATOM   5584 C CB  . ILE E 5  133 ? -58.52081 -41.99514 58.00363  1.000 28.55581 ? 147 ILE E CB  1 
ATOM   5585 C CG1 . ILE E 5  133 ? -57.81859 -41.70732 56.67294  1.000 29.00531 ? 147 ILE E CG1 1 
ATOM   5586 C CG2 . ILE E 5  133 ? -59.79550 -41.17130 58.13610  1.000 23.59424 ? 147 ILE E CG2 1 
ATOM   5587 C CD1 . ILE E 5  133 ? -58.44261 -42.40969 55.47769  1.000 27.62822 ? 147 ILE E CD1 1 
ATOM   5588 N N   . SER E 5  134 ? -58.73643 -42.73585 61.06465  1.000 25.10535 ? 148 SER E N   1 
ATOM   5589 C CA  . SER E 5  134 ? -59.49952 -42.69739 62.30744  1.000 31.38406 ? 148 SER E CA  1 
ATOM   5590 C C   . SER E 5  134 ? -58.61815 -42.36972 63.50793  1.000 32.35040 ? 148 SER E C   1 
ATOM   5591 O O   . SER E 5  134 ? -59.09132 -41.75670 64.47138  1.000 29.34343 ? 148 SER E O   1 
ATOM   5592 C CB  . SER E 5  134 ? -60.22062 -44.02889 62.51924  1.000 33.64421 ? 148 SER E CB  1 
ATOM   5593 O OG  . SER E 5  134 ? -59.36874 -44.98228 63.12845  1.000 45.02135 ? 148 SER E OG  1 
ATOM   5594 N N   . HIS E 5  135 ? -57.34126 -42.75491 63.46926  1.000 30.93182 ? 149 HIS E N   1 
ATOM   5595 C CA  . HIS E 5  135 ? -56.46390 -42.53733 64.61481  1.000 31.15054 ? 149 HIS E CA  1 
ATOM   5596 C C   . HIS E 5  135 ? -55.92617 -41.11229 64.67843  1.000 31.46257 ? 149 HIS E C   1 
ATOM   5597 O O   . HIS E 5  135 ? -55.70160 -40.59269 65.77677  1.000 34.01810 ? 149 HIS E O   1 
ATOM   5598 C CB  . HIS E 5  135 ? -55.29983 -43.53029 64.57838  1.000 29.02736 ? 149 HIS E CB  1 
ATOM   5599 C CG  . HIS E 5  135 ? -54.49474 -43.57264 65.84039  1.000 36.71856 ? 149 HIS E CG  1 
ATOM   5600 N ND1 . HIS E 5  135 ? -54.92887 -44.21542 66.97980  1.000 33.25177 ? 149 HIS E ND1 1 
ATOM   5601 C CD2 . HIS E 5  135 ? -53.27555 -43.06357 66.13764  1.000 29.31567 ? 149 HIS E CD2 1 
ATOM   5602 C CE1 . HIS E 5  135 ? -54.01510 -44.09532 67.92631  1.000 33.32784 ? 149 HIS E CE1 1 
ATOM   5603 N NE2 . HIS E 5  135 ? -53.00174 -43.40072 67.44111  1.000 34.31002 ? 149 HIS E NE2 1 
ATOM   5604 N N   . THR E 5  136 ? -55.71342 -40.46437 63.52941  1.000 26.19717 ? 150 THR E N   1 
ATOM   5605 C CA  . THR E 5  136 ? -55.04215 -39.17075 63.49672  1.000 28.42374 ? 150 THR E CA  1 
ATOM   5606 C C   . THR E 5  136 ? -55.81361 -38.06795 62.78681  1.000 26.35914 ? 150 THR E C   1 
ATOM   5607 O O   . THR E 5  136 ? -55.37367 -36.91341 62.83957  1.000 27.23998 ? 150 THR E O   1 
ATOM   5608 C CB  . THR E 5  136 ? -53.66380 -39.29405 62.82271  1.000 31.46674 ? 150 THR E CB  1 
ATOM   5609 O OG1 . THR E 5  136 ? -53.83631 -39.51018 61.41708  1.000 31.16070 ? 150 THR E OG1 1 
ATOM   5610 C CG2 . THR E 5  136 ? -52.86936 -40.44926 63.41273  1.000 30.96656 ? 150 THR E CG2 1 
ATOM   5611 N N   . GLN E 5  137 ? -56.93185 -38.37582 62.12642  1.000 28.66196 ? 151 GLN E N   1 
ATOM   5612 C CA  . GLN E 5  137 ? -57.64799 -37.41657 61.28155  1.000 30.08635 ? 151 GLN E CA  1 
ATOM   5613 C C   . GLN E 5  137 ? -56.75023 -36.85970 60.17840  1.000 31.42353 ? 151 GLN E C   1 
ATOM   5614 O O   . GLN E 5  137 ? -56.94504 -35.73427 59.71115  1.000 24.45315 ? 151 GLN E O   1 
ATOM   5615 C CB  . GLN E 5  137 ? -58.25463 -36.27644 62.10675  1.000 28.57006 ? 151 GLN E CB  1 
ATOM   5616 C CG  . GLN E 5  137 ? -59.20513 -36.73608 63.20382  1.000 34.21520 ? 151 GLN E CG  1 
ATOM   5617 C CD  . GLN E 5  137 ? -60.18344 -37.79181 62.72709  1.000 42.42384 ? 151 GLN E CD  1 
ATOM   5618 O OE1 . GLN E 5  137 ? -60.82188 -37.64123 61.68370  1.000 47.18225 ? 151 GLN E OE1 1 
ATOM   5619 N NE2 . GLN E 5  137 ? -60.30588 -38.87079 63.49208  1.000 48.29994 ? 151 GLN E NE2 1 
ATOM   5620 N N   . LYS E 5  138 ? -55.75818 -37.64531 59.76199  1.000 29.00704 ? 152 LYS E N   1 
ATOM   5621 C CA  . LYS E 5  138 ? -54.87539 -37.29925 58.65830  1.000 27.61400 ? 152 LYS E CA  1 
ATOM   5622 C C   . LYS E 5  138 ? -54.72265 -38.51177 57.74897  1.000 22.24980 ? 152 LYS E C   1 
ATOM   5623 O O   . LYS E 5  138 ? -54.95770 -39.65202 58.15669  1.000 24.66996 ? 152 LYS E O   1 
ATOM   5624 C CB  . LYS E 5  138 ? -53.50358 -36.82169 59.16118  1.000 27.32670 ? 152 LYS E CB  1 
ATOM   5625 C CG  . LYS E 5  138 ? -53.55855 -35.51556 59.94500  1.000 25.51999 ? 152 LYS E CG  1 
ATOM   5626 C CD  . LYS E 5  138 ? -52.19819 -35.13584 60.50546  1.000 29.44531 ? 152 LYS E CD  1 
ATOM   5627 C CE  . LYS E 5  138 ? -52.27736 -33.85232 61.32138  1.000 34.45107 ? 152 LYS E CE  1 
ATOM   5628 N NZ  . LYS E 5  138 ? -53.15100 -34.00101 62.51998  1.000 29.79713 ? 152 LYS E NZ  1 
ATOM   5629 N N   . ALA E 5  139 ? -54.32494 -38.25731 56.50384  1.000 22.96569 ? 153 ALA E N   1 
ATOM   5630 C CA  . ALA E 5  139 ? -54.27659 -39.29883 55.48272  1.000 23.72023 ? 153 ALA E CA  1 
ATOM   5631 C C   . ALA E 5  139 ? -52.99022 -39.16413 54.68332  1.000 24.78849 ? 153 ALA E C   1 
ATOM   5632 O O   . ALA E 5  139 ? -52.75230 -38.12350 54.06248  1.000 19.50642 ? 153 ALA E O   1 
ATOM   5633 C CB  . ALA E 5  139 ? -55.49491 -39.21250 54.56010  1.000 18.76148 ? 153 ALA E CB  1 
ATOM   5634 N N   . THR E 5  140 ? -52.17331 -40.21720 54.68610  1.000 21.32588 ? 154 THR E N   1 
ATOM   5635 C CA  . THR E 5  140 ? -50.88683 -40.21804 53.99963  1.000 23.62761 ? 154 THR E CA  1 
ATOM   5636 C C   . THR E 5  140 ? -50.97638 -41.04734 52.72339  1.000 22.15355 ? 154 THR E C   1 
ATOM   5637 O O   . THR E 5  140 ? -51.30319 -42.23827 52.77275  1.000 22.69382 ? 154 THR E O   1 
ATOM   5638 C CB  . THR E 5  140 ? -49.77974 -40.76699 54.90035  1.000 22.79541 ? 154 THR E CB  1 
ATOM   5639 O OG1 . THR E 5  140 ? -49.74484 -40.03089 56.12843  1.000 19.72561 ? 154 THR E OG1 1 
ATOM   5640 C CG2 . THR E 5  140 ? -48.42485 -40.64909 54.20520  1.000 15.91864 ? 154 THR E CG2 1 
ATOM   5641 N N   . LEU E 5  141 ? -50.68214 -40.41466 51.58951  1.000 23.12227 ? 155 LEU E N   1 
ATOM   5642 C CA  . LEU E 5  141 ? -50.49940 -41.10812 50.32150  1.000 23.12332 ? 155 LEU E CA  1 
ATOM   5643 C C   . LEU E 5  141 ? -49.02104 -41.42252 50.13867  1.000 24.40799 ? 155 LEU E C   1 
ATOM   5644 O O   . LEU E 5  141 ? -48.16285 -40.59891 50.46052  1.000 26.09449 ? 155 LEU E O   1 
ATOM   5645 C CB  . LEU E 5  141 ? -50.98213 -40.24922 49.14808  1.000 24.84338 ? 155 LEU E CB  1 
ATOM   5646 C CG  . LEU E 5  141 ? -52.46377 -40.01860 48.82940  1.000 26.76021 ? 155 LEU E CG  1 
ATOM   5647 C CD1 . LEU E 5  141 ? -53.14459 -41.32178 48.44634  1.000 33.42760 ? 155 LEU E CD1 1 
ATOM   5648 C CD2 . LEU E 5  141 ? -53.19809 -39.32423 49.96916  1.000 22.74333 ? 155 LEU E CD2 1 
ATOM   5649 N N   . VAL E 5  142 ? -48.72332 -42.60910 49.61392  1.000 20.92928 ? 156 VAL E N   1 
ATOM   5650 C CA  . VAL E 5  142 ? -47.35188 -43.01266 49.32170  1.000 25.19378 ? 156 VAL E CA  1 
ATOM   5651 C C   . VAL E 5  142 ? -47.25004 -43.35491 47.84204  1.000 30.75477 ? 156 VAL E C   1 
ATOM   5652 O O   . VAL E 5  142 ? -48.10923 -44.05943 47.29815  1.000 27.39756 ? 156 VAL E O   1 
ATOM   5653 C CB  . VAL E 5  142 ? -46.90069 -44.19752 50.19680  1.000 24.17141 ? 156 VAL E CB  1 
ATOM   5654 C CG1 . VAL E 5  142 ? -45.73662 -44.93792 49.55152  1.000 27.05324 ? 156 VAL E CG1 1 
ATOM   5655 C CG2 . VAL E 5  142 ? -46.50523 -43.70543 51.57812  1.000 22.40236 ? 156 VAL E CG2 1 
ATOM   5656 N N   . CYS E 5  143 ? -46.20725 -42.84412 47.19426  1.000 28.74929 ? 157 CYS E N   1 
ATOM   5657 C CA  . CYS E 5  143 ? -45.91592 -43.13168 45.79823  1.000 25.07320 ? 157 CYS E CA  1 
ATOM   5658 C C   . CYS E 5  143 ? -44.58977 -43.87145 45.71828  1.000 25.34091 ? 157 CYS E C   1 
ATOM   5659 O O   . CYS E 5  143 ? -43.58862 -43.41789 46.28265  1.000 25.15524 ? 157 CYS E O   1 
ATOM   5660 C CB  . CYS E 5  143 ? -45.86367 -41.84200 44.97613  1.000 22.14248 ? 157 CYS E CB  1 
ATOM   5661 S SG  . CYS E 5  143 ? -45.32339 -42.03790 43.26046  1.000 33.36722 ? 157 CYS E SG  1 
ATOM   5662 N N   . LEU E 5  144 ? -44.58824 -45.01113 45.03215  1.000 25.23521 ? 158 LEU E N   1 
ATOM   5663 C CA  . LEU E 5  144 ? -43.38527 -45.80316 44.81494  1.000 20.85194 ? 158 LEU E CA  1 
ATOM   5664 C C   . LEU E 5  144 ? -43.01802 -45.77844 43.33801  1.000 27.72355 ? 158 LEU E C   1 
ATOM   5665 O O   . LEU E 5  144 ? -43.84577 -46.10884 42.48246  1.000 22.47772 ? 158 LEU E O   1 
ATOM   5666 C CB  . LEU E 5  144 ? -43.57821 -47.25194 45.27125  1.000 20.35067 ? 158 LEU E CB  1 
ATOM   5667 C CG  . LEU E 5  144 ? -43.71642 -47.58863 46.75725  1.000 31.71364 ? 158 LEU E CG  1 
ATOM   5668 C CD1 . LEU E 5  144 ? -43.62246 -49.09596 46.94248  1.000 29.69086 ? 158 LEU E CD1 1 
ATOM   5669 C CD2 . LEU E 5  144 ? -42.66241 -46.87840 47.59549  1.000 26.41514 ? 158 LEU E CD2 1 
ATOM   5670 N N   . ALA E 5  145 ? -41.78293 -45.38393 43.04532  1.000 24.32236 ? 159 ALA E N   1 
ATOM   5671 C CA  . ALA E 5  145 ? -41.19866 -45.50866 41.71636  1.000 25.03079 ? 159 ALA E CA  1 
ATOM   5672 C C   . ALA E 5  145 ? -40.07844 -46.53422 41.80501  1.000 25.73825 ? 159 ALA E C   1 
ATOM   5673 O O   . ALA E 5  145 ? -39.11794 -46.33903 42.55615  1.000 24.17534 ? 159 ALA E O   1 
ATOM   5674 C CB  . ALA E 5  145 ? -40.67393 -44.16523 41.21155  1.000 23.89882 ? 159 ALA E CB  1 
ATOM   5675 N N   . THR E 5  146 ? -40.20672 -47.62773 41.05674  1.000 21.94086 ? 160 THR E N   1 
ATOM   5676 C CA  . THR E 5  146 ? -39.32816 -48.77518 41.22298  1.000 24.15741 ? 160 THR E CA  1 
ATOM   5677 C C   . THR E 5  146 ? -38.79577 -49.25123 39.87827  1.000 28.40663 ? 160 THR E C   1 
ATOM   5678 O O   . THR E 5  146 ? -39.39491 -49.01991 38.82462  1.000 27.55716 ? 160 THR E O   1 
ATOM   5679 C CB  . THR E 5  146 ? -40.05004 -49.93816 41.92063  1.000 24.39233 ? 160 THR E CB  1 
ATOM   5680 O OG1 . THR E 5  146 ? -41.25597 -50.24503 41.21008  1.000 25.84451 ? 160 THR E OG1 1 
ATOM   5681 C CG2 . THR E 5  146 ? -40.38814 -49.57841 43.36656  1.000 25.76417 ? 160 THR E CG2 1 
ATOM   5682 N N   . GLY E 5  147 ? -37.64840 -49.92486 39.93839  1.000 30.11521 ? 161 GLY E N   1 
ATOM   5683 C CA  . GLY E 5  147 ? -37.10606 -50.62626 38.79270  1.000 25.79227 ? 161 GLY E CA  1 
ATOM   5684 C C   . GLY E 5  147 ? -36.53422 -49.76469 37.69174  1.000 28.69592 ? 161 GLY E C   1 
ATOM   5685 O O   . GLY E 5  147 ? -36.41513 -50.23677 36.55906  1.000 31.20768 ? 161 GLY E O   1 
ATOM   5686 N N   . PHE E 5  148 ? -36.16359 -48.52067 37.97875  1.000 24.96726 ? 162 PHE E N   1 
ATOM   5687 C CA  . PHE E 5  148 ? -35.63741 -47.64245 36.94499  1.000 26.55950 ? 162 PHE E CA  1 
ATOM   5688 C C   . PHE E 5  148 ? -34.11298 -47.61942 36.96803  1.000 32.35507 ? 162 PHE E C   1 
ATOM   5689 O O   . PHE E 5  148 ? -33.47991 -47.81901 38.00814  1.000 27.65905 ? 162 PHE E O   1 
ATOM   5690 C CB  . PHE E 5  148 ? -36.18811 -46.21771 37.08022  1.000 27.63234 ? 162 PHE E CB  1 
ATOM   5691 C CG  . PHE E 5  148 ? -35.95233 -45.58081 38.42428  1.000 24.16745 ? 162 PHE E CG  1 
ATOM   5692 C CD1 . PHE E 5  148 ? -36.86665 -45.74139 39.45335  1.000 26.70272 ? 162 PHE E CD1 1 
ATOM   5693 C CD2 . PHE E 5  148 ? -34.83787 -44.78753 38.64432  1.000 25.41849 ? 162 PHE E CD2 1 
ATOM   5694 C CE1 . PHE E 5  148 ? -36.66220 -45.14433 40.68361  1.000 22.57257 ? 162 PHE E CE1 1 
ATOM   5695 C CE2 . PHE E 5  148 ? -34.62761 -44.18614 39.87178  1.000 32.11961 ? 162 PHE E CE2 1 
ATOM   5696 C CZ  . PHE E 5  148 ? -35.54210 -44.36511 40.89409  1.000 25.05792 ? 162 PHE E CZ  1 
ATOM   5697 N N   . PHE E 5  149 ? -33.53294 -47.39004 35.79115  1.000 25.56058 ? 163 PHE E N   1 
ATOM   5698 C CA  . PHE E 5  149 ? -32.09358 -47.26774 35.60252  1.000 33.33231 ? 163 PHE E CA  1 
ATOM   5699 C C   . PHE E 5  149 ? -31.82425 -46.46953 34.33226  1.000 29.49102 ? 163 PHE E C   1 
ATOM   5700 O O   . PHE E 5  149 ? -32.39456 -46.77626 33.27740  1.000 28.73947 ? 163 PHE E O   1 
ATOM   5701 C CB  . PHE E 5  149 ? -31.42666 -48.64232 35.52278  1.000 26.11002 ? 163 PHE E CB  1 
ATOM   5702 C CG  . PHE E 5  149 ? -29.92651 -48.58736 35.55974  1.000 33.74251 ? 163 PHE E CG  1 
ATOM   5703 C CD1 . PHE E 5  149 ? -29.25170 -48.51247 36.76616  1.000 32.94460 ? 163 PHE E CD1 1 
ATOM   5704 C CD2 . PHE E 5  149 ? -29.19099 -48.59469 34.38577  1.000 32.79510 ? 163 PHE E CD2 1 
ATOM   5705 C CE1 . PHE E 5  149 ? -27.87001 -48.45617 36.80277  1.000 35.20766 ? 163 PHE E CE1 1 
ATOM   5706 C CE2 . PHE E 5  149 ? -27.81228 -48.53960 34.41498  1.000 36.21778 ? 163 PHE E CE2 1 
ATOM   5707 C CZ  . PHE E 5  149 ? -27.14920 -48.46888 35.62472  1.000 36.15646 ? 163 PHE E CZ  1 
ATOM   5708 N N   . PRO E 5  150 ? -30.97275 -45.43315 34.38505  1.000 29.18793 ? 164 PRO E N   1 
ATOM   5709 C CA  . PRO E 5  150 ? -30.24704 -44.95934 35.56954  1.000 31.86358 ? 164 PRO E CA  1 
ATOM   5710 C C   . PRO E 5  150 ? -31.13358 -44.14235 36.51154  1.000 30.38383 ? 164 PRO E C   1 
ATOM   5711 O O   . PRO E 5  150 ? -32.34147 -44.06128 36.28457  1.000 28.53133 ? 164 PRO E O   1 
ATOM   5712 C CB  . PRO E 5  150 ? -29.14242 -44.09326 34.96521  1.000 30.18323 ? 164 PRO E CB  1 
ATOM   5713 C CG  . PRO E 5  150 ? -29.77440 -43.52838 33.73805  1.000 31.97920 ? 164 PRO E CG  1 
ATOM   5714 C CD  . PRO E 5  150 ? -30.66061 -44.62235 33.19400  1.000 28.04789 ? 164 PRO E CD  1 
ATOM   5715 N N   . ASP E 5  151 ? -30.54643 -43.54097 37.54825  1.000 31.85629 ? 165 ASP E N   1 
ATOM   5716 C CA  . ASP E 5  151 ? -31.33751 -42.80832 38.53233  1.000 29.97457 ? 165 ASP E CA  1 
ATOM   5717 C C   . ASP E 5  151 ? -31.63988 -41.38627 38.07040  1.000 30.69090 ? 165 ASP E C   1 
ATOM   5718 O O   . ASP E 5  151 ? -31.48241 -40.42979 38.83590  1.000 39.38874 ? 165 ASP E O   1 
ATOM   5719 C CB  . ASP E 5  151 ? -30.63247 -42.79614 39.89612  1.000 37.44066 ? 165 ASP E CB  1 
ATOM   5720 C CG  . ASP E 5  151 ? -29.26881 -42.11369 39.86253  1.000 41.25187 ? 165 ASP E CG  1 
ATOM   5721 O OD1 . ASP E 5  151 ? -28.83877 -41.64750 38.78666  1.000 45.26410 ? 165 ASP E OD1 1 
ATOM   5722 O OD2 . ASP E 5  151 ? -28.62726 -42.03596 40.93149  1.000 37.53267 ? 165 ASP E OD2 1 
ATOM   5723 N N   . HIS E 5  152 ? -32.09089 -41.23875 36.82465  1.000 28.00937 ? 166 HIS E N   1 
ATOM   5724 C CA  . HIS E 5  152 ? -32.41056 -39.93010 36.25585  1.000 28.61992 ? 166 HIS E CA  1 
ATOM   5725 C C   . HIS E 5  152 ? -33.92295 -39.73106 36.32385  1.000 30.77924 ? 166 HIS E C   1 
ATOM   5726 O O   . HIS E 5  152 ? -34.64168 -39.85323 35.33181  1.000 26.38136 ? 166 HIS E O   1 
ATOM   5727 C CB  . HIS E 5  152 ? -31.89192 -39.82750 34.82464  1.000 26.40383 ? 166 HIS E CB  1 
ATOM   5728 C CG  . HIS E 5  152 ? -30.40144 -39.91530 34.71036  1.000 30.97118 ? 166 HIS E CG  1 
ATOM   5729 N ND1 . HIS E 5  152 ? -29.74636 -39.87323 33.49868  1.000 29.53676 ? 166 HIS E ND1 1 
ATOM   5730 C CD2 . HIS E 5  152 ? -29.43843 -40.04231 35.65391  1.000 32.03925 ? 166 HIS E CD2 1 
ATOM   5731 C CE1 . HIS E 5  152 ? -28.44448 -39.97152 33.70017  1.000 30.25381 ? 166 HIS E CE1 1 
ATOM   5732 N NE2 . HIS E 5  152 ? -28.23099 -40.07597 34.99921  1.000 33.90663 ? 166 HIS E NE2 1 
ATOM   5733 N N   . VAL E 5  153 ? -34.40971 -39.41582 37.52389  1.000 23.30290 ? 167 VAL E N   1 
ATOM   5734 C CA  . VAL E 5  153 ? -35.83680 -39.23596 37.75623  1.000 28.73288 ? 167 VAL E CA  1 
ATOM   5735 C C   . VAL E 5  153 ? -36.07286 -37.98709 38.59359  1.000 30.22188 ? 167 VAL E C   1 
ATOM   5736 O O   . VAL E 5  153 ? -35.23767 -37.59346 39.41442  1.000 26.80155 ? 167 VAL E O   1 
ATOM   5737 C CB  . VAL E 5  153 ? -36.47128 -40.46361 38.44767  1.000 26.45809 ? 167 VAL E CB  1 
ATOM   5738 C CG1 . VAL E 5  153 ? -36.51718 -41.65142 37.49832  1.000 27.00659 ? 167 VAL E CG1 1 
ATOM   5739 C CG2 . VAL E 5  153 ? -35.71326 -40.80693 39.72331  1.000 35.28752 ? 167 VAL E CG2 1 
ATOM   5740 N N   . GLU E 5  154 ? -37.22908 -37.36262 38.37316  1.000 25.42442 ? 168 GLU E N   1 
ATOM   5741 C CA  . GLU E 5  154 ? -37.72645 -36.27049 39.19997  1.000 26.81581 ? 168 GLU E CA  1 
ATOM   5742 C C   . GLU E 5  154 ? -39.18423 -36.54887 39.53228  1.000 29.73785 ? 168 GLU E C   1 
ATOM   5743 O O   . GLU E 5  154 ? -40.00158 -36.74894 38.62771  1.000 25.38723 ? 168 GLU E O   1 
ATOM   5744 C CB  . GLU E 5  154 ? -37.59652 -34.91501 38.49587  1.000 25.60646 ? 168 GLU E CB  1 
ATOM   5745 C CG  . GLU E 5  154 ? -36.21592 -34.61730 37.93791  1.000 34.93048 ? 168 GLU E CG  1 
ATOM   5746 C CD  . GLU E 5  154 ? -36.22116 -33.44645 36.97404  1.000 39.54444 ? 168 GLU E CD  1 
ATOM   5747 O OE1 . GLU E 5  154 ? -37.27061 -33.19671 36.34247  1.000 43.71021 ? 168 GLU E OE1 1 
ATOM   5748 O OE2 . GLU E 5  154 ? -35.17620 -32.77498 36.84871  1.000 42.55822 ? 168 GLU E OE2 1 
ATOM   5749 N N   . LEU E 5  155 ? -39.50625 -36.56048 40.82232  1.000 24.77222 ? 169 LEU E N   1 
ATOM   5750 C CA  . LEU E 5  155 ? -40.83935 -36.89376 41.30277  1.000 24.45313 ? 169 LEU E CA  1 
ATOM   5751 C C   . LEU E 5  155 ? -41.54055 -35.64140 41.81236  1.000 27.13724 ? 169 LEU E C   1 
ATOM   5752 O O   . LEU E 5  155 ? -40.93895 -34.82521 42.51822  1.000 27.32644 ? 169 LEU E O   1 
ATOM   5753 C CB  . LEU E 5  155 ? -40.76666 -37.94525 42.41606  1.000 23.22926 ? 169 LEU E CB  1 
ATOM   5754 C CG  . LEU E 5  155 ? -42.06867 -38.56279 42.93656  1.000 24.93211 ? 169 LEU E CG  1 
ATOM   5755 C CD1 . LEU E 5  155 ? -41.82599 -39.99053 43.40632  1.000 21.94325 ? 169 LEU E CD1 1 
ATOM   5756 C CD2 . LEU E 5  155 ? -42.67501 -37.73116 44.05907  1.000 19.28672 ? 169 LEU E CD2 1 
ATOM   5757 N N   . SER E 5  156 ? -42.81962 -35.50168 41.46488  1.000 25.08617 ? 170 SER E N   1 
ATOM   5758 C CA  . SER E 5  156 ? -43.63030 -34.38886 41.93622  1.000 28.90479 ? 170 SER E CA  1 
ATOM   5759 C C   . SER E 5  156 ? -45.05342 -34.86436 42.19543  1.000 27.63773 ? 170 SER E C   1 
ATOM   5760 O O   . SER E 5  156 ? -45.51684 -35.84291 41.60356  1.000 25.81542 ? 170 SER E O   1 
ATOM   5761 C CB  . SER E 5  156 ? -43.63601 -33.22634 40.93293  1.000 26.39154 ? 170 SER E CB  1 
ATOM   5762 O OG  . SER E 5  156 ? -43.97722 -33.67124 39.63266  1.000 29.67645 ? 170 SER E OG  1 
ATOM   5763 N N   . TRP E 5  157 ? -45.73834 -34.16050 43.09420  1.000 25.21115 ? 171 TRP E N   1 
ATOM   5764 C CA  . TRP E 5  157 ? -47.12716 -34.43192 43.43842  1.000 23.97695 ? 171 TRP E CA  1 
ATOM   5765 C C   . TRP E 5  157 ? -48.02386 -33.35993 42.83438  1.000 22.84578 ? 171 TRP E C   1 
ATOM   5766 O O   . TRP E 5  157 ? -47.65793 -32.18086 42.79808  1.000 24.94237 ? 171 TRP E O   1 
ATOM   5767 C CB  . TRP E 5  157 ? -47.32648 -34.46442 44.95629  1.000 24.50312 ? 171 TRP E CB  1 
ATOM   5768 C CG  . TRP E 5  157 ? -46.83827 -35.71125 45.62520  1.000 25.48957 ? 171 TRP E CG  1 
ATOM   5769 C CD1 . TRP E 5  157 ? -45.62289 -35.90203 46.21471  1.000 23.42256 ? 171 TRP E CD1 1 
ATOM   5770 C CD2 . TRP E 5  157 ? -47.56306 -36.93613 45.79454  1.000 25.96232 ? 171 TRP E CD2 1 
ATOM   5771 N NE1 . TRP E 5  157 ? -45.54294 -37.17130 46.73491  1.000 25.53128 ? 171 TRP E NE1 1 
ATOM   5772 C CE2 . TRP E 5  157 ? -46.72095 -37.82647 46.48986  1.000 25.50699 ? 171 TRP E CE2 1 
ATOM   5773 C CE3 . TRP E 5  157 ? -48.84033 -37.36721 45.42281  1.000 21.06877 ? 171 TRP E CE3 1 
ATOM   5774 C CZ2 . TRP E 5  157 ? -47.11482 -39.12075 46.82179  1.000 23.46862 ? 171 TRP E CZ2 1 
ATOM   5775 C CZ3 . TRP E 5  157 ? -49.22855 -38.65321 45.75179  1.000 21.01804 ? 171 TRP E CZ3 1 
ATOM   5776 C CH2 . TRP E 5  157 ? -48.36887 -39.51478 46.44357  1.000 20.05410 ? 171 TRP E CH2 1 
ATOM   5777 N N   . TRP E 5  158 ? -49.20415 -33.76824 42.37242  1.000 21.88475 ? 172 TRP E N   1 
ATOM   5778 C CA  . TRP E 5  158 ? -50.15442 -32.85554 41.74683  1.000 26.91161 ? 172 TRP E CA  1 
ATOM   5779 C C   . TRP E 5  158 ? -51.53198 -33.07639 42.35178  1.000 28.76461 ? 172 TRP E C   1 
ATOM   5780 O O   . TRP E 5  158 ? -52.04533 -34.20021 42.34098  1.000 26.90431 ? 172 TRP E O   1 
ATOM   5781 C CB  . TRP E 5  158 ? -50.18642 -33.05248 40.22912  1.000 26.98441 ? 172 TRP E CB  1 
ATOM   5782 C CG  . TRP E 5  158 ? -48.86755 -32.76015 39.58160  1.000 33.32255 ? 172 TRP E CG  1 
ATOM   5783 C CD1 . TRP E 5  158 ? -47.76591 -33.56647 39.56437  1.000 29.71448 ? 172 TRP E CD1 1 
ATOM   5784 C CD2 . TRP E 5  158 ? -48.50329 -31.56887 38.87496  1.000 30.20540 ? 172 TRP E CD2 1 
ATOM   5785 N NE1 . TRP E 5  158 ? -46.74211 -32.95464 38.88395  1.000 31.02101 ? 172 TRP E NE1 1 
ATOM   5786 C CE2 . TRP E 5  158 ? -47.16874 -31.72707 38.45034  1.000 33.37708 ? 172 TRP E CE2 1 
ATOM   5787 C CE3 . TRP E 5  158 ? -49.17649 -30.38567 38.55694  1.000 32.50767 ? 172 TRP E CE3 1 
ATOM   5788 C CZ2 . TRP E 5  158 ? -46.49536 -30.74766 37.72292  1.000 32.30880 ? 172 TRP E CZ2 1 
ATOM   5789 C CZ3 . TRP E 5  158 ? -48.50587 -29.41379 37.83499  1.000 33.58743 ? 172 TRP E CZ3 1 
ATOM   5790 C CH2 . TRP E 5  158 ? -47.17920 -29.60109 37.42616  1.000 31.46090 ? 172 TRP E CH2 1 
ATOM   5791 N N   . VAL E 5  159 ? -52.12318 -32.00658 42.87772  1.000 28.38467 ? 173 VAL E N   1 
ATOM   5792 C CA  . VAL E 5  159 ? -53.44227 -32.04253 43.49953  1.000 26.20527 ? 173 VAL E CA  1 
ATOM   5793 C C   . VAL E 5  159 ? -54.35848 -31.12834 42.69846  1.000 29.71835 ? 173 VAL E C   1 
ATOM   5794 O O   . VAL E 5  159 ? -54.10819 -29.91954 42.60467  1.000 31.96464 ? 173 VAL E O   1 
ATOM   5795 C CB  . VAL E 5  159 ? -53.39109 -31.61584 44.97583  1.000 30.52876 ? 173 VAL E CB  1 
ATOM   5796 C CG1 . VAL E 5  159 ? -54.79326 -31.55978 45.56634  1.000 23.72281 ? 173 VAL E CG1 1 
ATOM   5797 C CG2 . VAL E 5  159 ? -52.51020 -32.56645 45.77417  1.000 24.05808 ? 173 VAL E CG2 1 
ATOM   5798 N N   . ASN E 5  160 ? -55.41153 -31.70754 42.11852  1.000 30.89332 ? 174 ASN E N   1 
ATOM   5799 C CA  . ASN E 5  160 ? -56.36693 -30.97236 41.28594  1.000 32.15240 ? 174 ASN E CA  1 
ATOM   5800 C C   . ASN E 5  160 ? -55.66118 -30.21150 40.16438  1.000 34.22214 ? 174 ASN E C   1 
ATOM   5801 O O   . ASN E 5  160 ? -56.01445 -29.07788 39.83215  1.000 35.40294 ? 174 ASN E O   1 
ATOM   5802 C CB  . ASN E 5  160 ? -57.22455 -30.03098 42.13400  1.000 28.28944 ? 174 ASN E CB  1 
ATOM   5803 C CG  . ASN E 5  160 ? -58.12762 -30.77817 43.09521  1.000 28.81288 ? 174 ASN E CG  1 
ATOM   5804 O OD1 . ASN E 5  160 ? -58.60738 -31.86954 42.78920  1.000 30.57339 ? 174 ASN E OD1 1 
ATOM   5805 N ND2 . ASN E 5  160 ? -58.36125 -30.19580 44.26602  1.000 27.35346 ? 174 ASN E ND2 1 
ATOM   5806 N N   . GLY E 5  161 ? -54.64647 -30.84328 39.57736  1.000 29.62921 ? 175 GLY E N   1 
ATOM   5807 C CA  . GLY E 5  161 ? -53.93793 -30.26521 38.45355  1.000 33.62039 ? 175 GLY E CA  1 
ATOM   5808 C C   . GLY E 5  161 ? -52.89238 -29.22949 38.79905  1.000 35.55675 ? 175 GLY E C   1 
ATOM   5809 O O   . GLY E 5  161 ? -52.32973 -28.61603 37.88523  1.000 36.88462 ? 175 GLY E O   1 
ATOM   5810 N N   . LYS E 5  162 ? -52.60995 -29.01280 40.08063  1.000 36.29492 ? 176 LYS E N   1 
ATOM   5811 C CA  . LYS E 5  162 ? -51.62272 -28.03635 40.51825  1.000 35.75873 ? 176 LYS E CA  1 
ATOM   5812 C C   . LYS E 5  162 ? -50.57050 -28.72356 41.37720  1.000 37.60295 ? 176 LYS E C   1 
ATOM   5813 O O   . LYS E 5  162 ? -50.90004 -29.54963 42.23532  1.000 28.57268 ? 176 LYS E O   1 
ATOM   5814 C CB  . LYS E 5  162 ? -52.28298 -26.89769 41.30626  1.000 32.55047 ? 176 LYS E CB  1 
ATOM   5815 C CG  . LYS E 5  162 ? -52.54291 -25.64210 40.48730  1.000 51.32343 ? 176 LYS E CG  1 
ATOM   5816 C CD  . LYS E 5  162 ? -53.95484 -25.63170 39.91546  1.000 56.38351 ? 176 LYS E CD  1 
ATOM   5817 C CE  . LYS E 5  162 ? -54.02679 -24.82403 38.62616  1.000 61.95903 ? 176 LYS E CE  1 
ATOM   5818 N NZ  . LYS E 5  162 ? -55.25887 -25.12387 37.84137  1.000 59.90889 ? 176 LYS E NZ  1 
ATOM   5819 N N   . GLU E 5  163 ? -49.30491 -28.38139 41.14320  1.000 34.04587 ? 177 GLU E N   1 
ATOM   5820 C CA  . GLU E 5  163 ? -48.22016 -28.97968 41.90896  1.000 28.06572 ? 177 GLU E CA  1 
ATOM   5821 C C   . GLU E 5  163 ? -48.23456 -28.46983 43.34450  1.000 30.50453 ? 177 GLU E C   1 
ATOM   5822 O O   . GLU E 5  163 ? -48.42922 -27.27756 43.59779  1.000 35.39351 ? 177 GLU E O   1 
ATOM   5823 C CB  . GLU E 5  163 ? -46.86810 -28.67882 41.25967  1.000 25.36870 ? 177 GLU E CB  1 
ATOM   5824 C CG  . GLU E 5  163 ? -45.68620 -29.20680 42.06010  1.000 29.36661 ? 177 GLU E CG  1 
ATOM   5825 C CD  . GLU E 5  163 ? -44.39074 -29.24197 41.27211  1.000 37.20370 ? 177 GLU E CD  1 
ATOM   5826 O OE1 . GLU E 5  163 ? -44.36952 -28.75297 40.12238  1.000 42.40929 ? 177 GLU E OE1 1 
ATOM   5827 O OE2 . GLU E 5  163 ? -43.39088 -29.76441 41.80933  1.000 34.54384 ? 177 GLU E OE2 1 
ATOM   5828 N N   . VAL E 5  164 ? -48.02476 -29.38574 44.28816  1.000 29.18019 ? 178 VAL E N   1 
ATOM   5829 C CA  . VAL E 5  164 ? -48.02996 -29.06558 45.70724  1.000 31.55004 ? 178 VAL E CA  1 
ATOM   5830 C C   . VAL E 5  164 ? -46.67794 -29.43357 46.30417  1.000 32.79106 ? 178 VAL E C   1 
ATOM   5831 O O   . VAL E 5  164 ? -45.95102 -30.28793 45.79030  1.000 30.97294 ? 178 VAL E O   1 
ATOM   5832 C CB  . VAL E 5  164 ? -49.16790 -29.78516 46.45856  1.000 32.98452 ? 178 VAL E CB  1 
ATOM   5833 C CG1 . VAL E 5  164 ? -50.51996 -29.30309 45.95879  1.000 32.49703 ? 178 VAL E CG1 1 
ATOM   5834 C CG2 . VAL E 5  164 ? -49.03926 -31.29170 46.29344  1.000 30.62675 ? 178 VAL E CG2 1 
ATOM   5835 N N   . HIS E 5  165 ? -46.34674 -28.76787 47.40983  1.000 32.99566 ? 179 HIS E N   1 
ATOM   5836 C CA  . HIS E 5  165 ? -45.11380 -29.04588 48.13619  1.000 35.62281 ? 179 HIS E CA  1 
ATOM   5837 C C   . HIS E 5  165 ? -45.40230 -29.22840 49.61997  1.000 34.02054 ? 179 HIS E C   1 
ATOM   5838 O O   . HIS E 5  165 ? -44.68174 -29.95081 50.31600  1.000 32.60277 ? 179 HIS E O   1 
ATOM   5839 C CB  . HIS E 5  165 ? -44.09746 -27.92278 47.92422  1.000 29.23504 ? 179 HIS E CB  1 
ATOM   5840 C CG  . HIS E 5  165 ? -43.60502 -27.81393 46.51549  1.000 38.34092 ? 179 HIS E CG  1 
ATOM   5841 N ND1 . HIS E 5  165 ? -44.12718 -26.91351 45.61213  1.000 42.91300 ? 179 HIS E ND1 1 
ATOM   5842 C CD2 . HIS E 5  165 ? -42.63968 -28.49474 45.85310  1.000 37.27029 ? 179 HIS E CD2 1 
ATOM   5843 C CE1 . HIS E 5  165 ? -43.50348 -27.04275 44.45451  1.000 38.55583 ? 179 HIS E CE1 1 
ATOM   5844 N NE2 . HIS E 5  165 ? -42.59654 -27.99562 44.57395  1.000 38.50420 ? 179 HIS E NE2 1 
ATOM   5845 N N   . SER E 5  166 ? -46.45316 -28.57597 50.10926  1.000 37.01704 ? 180 SER E N   1 
ATOM   5846 C CA  . SER E 5  166 ? -46.83236 -28.70776 51.50818  1.000 39.57145 ? 180 SER E CA  1 
ATOM   5847 C C   . SER E 5  166 ? -47.30640 -30.12641 51.79886  1.000 35.71259 ? 180 SER E C   1 
ATOM   5848 O O   . SER E 5  166 ? -48.07983 -30.71006 51.03448  1.000 37.68431 ? 180 SER E O   1 
ATOM   5849 C CB  . SER E 5  166 ? -47.92929 -27.70157 51.85693  1.000 40.41476 ? 180 SER E CB  1 
ATOM   5850 O OG  . SER E 5  166 ? -48.30938 -27.80933 53.21763  1.000 47.03987 ? 180 SER E OG  1 
ATOM   5851 N N   . GLY E 5  167 ? -46.83275 -30.68231 52.91230  1.000 34.12273 ? 181 GLY E N   1 
ATOM   5852 C CA  . GLY E 5  167 ? -47.18934 -32.03569 53.28717  1.000 30.14225 ? 181 GLY E CA  1 
ATOM   5853 C C   . GLY E 5  167 ? -46.51097 -33.12419 52.48932  1.000 28.80378 ? 181 GLY E C   1 
ATOM   5854 O O   . GLY E 5  167 ? -46.93729 -34.28069 52.56176  1.000 27.30762 ? 181 GLY E O   1 
ATOM   5855 N N   . VAL E 5  168 ? -45.46349 -32.79464 51.73739  1.000 25.65705 ? 182 VAL E N   1 
ATOM   5856 C CA  . VAL E 5  168 ? -44.76231 -33.74186 50.87922  1.000 26.86754 ? 182 VAL E CA  1 
ATOM   5857 C C   . VAL E 5  168 ? -43.35992 -33.96148 51.42720  1.000 27.78767 ? 182 VAL E C   1 
ATOM   5858 O O   . VAL E 5  168 ? -42.69885 -33.01242 51.86516  1.000 26.93225 ? 182 VAL E O   1 
ATOM   5859 C CB  . VAL E 5  168 ? -44.70603 -33.23579 49.42283  1.000 29.25597 ? 182 VAL E CB  1 
ATOM   5860 C CG1 . VAL E 5  168 ? -43.63382 -33.97555 48.62732  1.000 24.45811 ? 182 VAL E CG1 1 
ATOM   5861 C CG2 . VAL E 5  168 ? -46.06608 -33.37534 48.75589  1.000 24.05364 ? 182 VAL E CG2 1 
ATOM   5862 N N   . CYS E 5  169 ? -42.91074 -35.21637 51.41158  1.000 24.89465 ? 183 CYS E N   1 
ATOM   5863 C CA  . CYS E 5  169 ? -41.50931 -35.54311 51.65389  1.000 27.10751 ? 183 CYS E CA  1 
ATOM   5864 C C   . CYS E 5  169 ? -41.08556 -36.62045 50.67032  1.000 22.63801 ? 183 CYS E C   1 
ATOM   5865 O O   . CYS E 5  169 ? -41.70886 -37.68274 50.60331  1.000 24.99133 ? 183 CYS E O   1 
ATOM   5866 C CB  . CYS E 5  169 ? -41.26779 -36.01133 53.09245  1.000 26.72490 ? 183 CYS E CB  1 
ATOM   5867 S SG  . CYS E 5  169 ? -39.57673 -35.71475 53.66314  1.000 47.09006 ? 183 CYS E SG  1 
ATOM   5868 N N   . THR E 5  170 ? -40.03341 -36.34549 49.90951  1.000 26.86750 ? 184 THR E N   1 
ATOM   5869 C CA  . THR E 5  170 ? -39.44964 -37.30836 48.98925  1.000 25.48673 ? 184 THR E CA  1 
ATOM   5870 C C   . THR E 5  170 ? -38.09010 -37.73893 49.52125  1.000 26.23703 ? 184 THR E C   1 
ATOM   5871 O O   . THR E 5  170 ? -37.37342 -36.93518 50.12561  1.000 29.99053 ? 184 THR E O   1 
ATOM   5872 C CB  . THR E 5  170 ? -39.30686 -36.70588 47.58746  1.000 26.77418 ? 184 THR E CB  1 
ATOM   5873 O OG1 . THR E 5  170 ? -40.58007 -36.21449 47.14837  1.000 24.70445 ? 184 THR E OG1 1 
ATOM   5874 C CG2 . THR E 5  170 ? -38.79554 -37.74542 46.59180  1.000 18.35706 ? 184 THR E CG2 1 
ATOM   5875 N N   . ASP E 5  171 ? -37.75315 -39.01054 49.32316  1.000 24.52173 ? 185 ASP E N   1 
ATOM   5876 C CA  . ASP E 5  171 ? -36.42772 -39.48740 49.68600  1.000 26.62934 ? 185 ASP E CA  1 
ATOM   5877 C C   . ASP E 5  171 ? -35.36762 -38.62780 48.99920  1.000 27.50182 ? 185 ASP E C   1 
ATOM   5878 O O   . ASP E 5  171 ? -35.51090 -38.29919 47.81393  1.000 23.11060 ? 185 ASP E O   1 
ATOM   5879 C CB  . ASP E 5  171 ? -36.25081 -40.95558 49.28617  1.000 25.00868 ? 185 ASP E CB  1 
ATOM   5880 C CG  . ASP E 5  171 ? -37.28354 -41.86713 49.92056  1.000 34.38544 ? 185 ASP E CG  1 
ATOM   5881 O OD1 . ASP E 5  171 ? -37.89571 -41.46961 50.93468  1.000 35.09842 ? 185 ASP E OD1 1 
ATOM   5882 O OD2 . ASP E 5  171 ? -37.47928 -42.98801 49.40413  1.000 34.29617 ? 185 ASP E OD2 1 
ATOM   5883 N N   . PRO E 5  172 ? -34.31027 -38.22657 49.70886  1.000 31.13236 ? 186 PRO E N   1 
ATOM   5884 C CA  . PRO E 5  172 ? -33.28750 -37.37652 49.07565  1.000 33.28641 ? 186 PRO E CA  1 
ATOM   5885 C C   . PRO E 5  172 ? -32.59036 -38.03053 47.89478  1.000 30.51829 ? 186 PRO E C   1 
ATOM   5886 O O   . PRO E 5  172 ? -32.14793 -37.31886 46.98486  1.000 32.29007 ? 186 PRO E O   1 
ATOM   5887 C CB  . PRO E 5  172 ? -32.30525 -37.08723 50.22289  1.000 30.46665 ? 186 PRO E CB  1 
ATOM   5888 C CG  . PRO E 5  172 ? -32.63632 -38.07850 51.30112  1.000 35.12016 ? 186 PRO E CG  1 
ATOM   5889 C CD  . PRO E 5  172 ? -34.08893 -38.38344 51.15465  1.000 24.61667 ? 186 PRO E CD  1 
ATOM   5890 N N   . GLN E 5  173 ? -32.47953 -39.35663 47.87021  1.000 27.22346 ? 187 GLN E N   1 
ATOM   5891 C CA  . GLN E 5  173 ? -31.81057 -40.03700 46.77076  1.000 35.93225 ? 187 GLN E CA  1 
ATOM   5892 C C   . GLN E 5  173 ? -32.39796 -41.43035 46.60945  1.000 34.75973 ? 187 GLN E C   1 
ATOM   5893 O O   . GLN E 5  173 ? -32.93344 -41.99090 47.57324  1.000 27.03153 ? 187 GLN E O   1 
ATOM   5894 C CB  . GLN E 5  173 ? -30.29303 -40.11504 46.99933  1.000 43.66001 ? 187 GLN E CB  1 
ATOM   5895 C CG  . GLN E 5  173 ? -29.87416 -40.91106 48.21909  1.000 41.26343 ? 187 GLN E CG  1 
ATOM   5896 C CD  . GLN E 5  173 ? -28.50444 -40.50349 48.72674  1.000 57.10466 ? 187 GLN E CD  1 
ATOM   5897 O OE1 . GLN E 5  173 ? -27.57996 -40.28584 47.94317  1.000 62.68896 ? 187 GLN E OE1 1 
ATOM   5898 N NE2 . GLN E 5  173 ? -28.36681 -40.39892 50.04365  1.000 66.10697 ? 187 GLN E NE2 1 
ATOM   5899 N N   . PRO E 5  174 ? -32.32387 -42.00872 45.41109  1.000 32.88545 ? 188 PRO E N   1 
ATOM   5900 C CA  . PRO E 5  174 ? -32.94040 -43.32059 45.18657  1.000 32.79371 ? 188 PRO E CA  1 
ATOM   5901 C C   . PRO E 5  174 ? -32.18988 -44.44533 45.88302  1.000 35.55624 ? 188 PRO E C   1 
ATOM   5902 O O   . PRO E 5  174 ? -30.97127 -44.39831 46.06806  1.000 38.28545 ? 188 PRO E O   1 
ATOM   5903 C CB  . PRO E 5  174 ? -32.88195 -43.48555 43.66136  1.000 39.61871 ? 188 PRO E CB  1 
ATOM   5904 C CG  . PRO E 5  174 ? -32.64640 -42.10609 43.12278  1.000 40.70870 ? 188 PRO E CG  1 
ATOM   5905 C CD  . PRO E 5  174 ? -31.82073 -41.42006 44.15994  1.000 32.92008 ? 188 PRO E CD  1 
ATOM   5906 N N   . LEU E 5  175 ? -32.94691 -45.47050 46.26458  1.000 36.04636 ? 189 LEU E N   1 
ATOM   5907 C CA  . LEU E 5  175 ? -32.38605 -46.68851 46.82868  1.000 36.66518 ? 189 LEU E CA  1 
ATOM   5908 C C   . LEU E 5  175 ? -31.95996 -47.64247 45.71943  1.000 38.96320 ? 189 LEU E C   1 
ATOM   5909 O O   . LEU E 5  175 ? -32.50949 -47.62820 44.61575  1.000 29.57487 ? 189 LEU E O   1 
ATOM   5910 C CB  . LEU E 5  175 ? -33.41188 -47.38661 47.72269  1.000 39.56687 ? 189 LEU E CB  1 
ATOM   5911 C CG  . LEU E 5  175 ? -33.40971 -47.13940 49.23030  1.000 57.31368 ? 189 LEU E CG  1 
ATOM   5912 C CD1 . LEU E 5  175 ? -34.49624 -47.97904 49.88778  1.000 42.62355 ? 189 LEU E CD1 1 
ATOM   5913 C CD2 . LEU E 5  175 ? -32.04936 -47.45179 49.83209  1.000 50.37868 ? 189 LEU E CD2 1 
ATOM   5914 N N   . LYS E 5  176 ? -30.98026 -48.48792 46.02805  1.000 40.67125 ? 190 LYS E N   1 
ATOM   5915 C CA  . LYS E 5  176 ? -30.56886 -49.55669 45.12730  1.000 33.06057 ? 190 LYS E CA  1 
ATOM   5916 C C   . LYS E 5  176 ? -31.36071 -50.81869 45.44620  1.000 37.86689 ? 190 LYS E C   1 
ATOM   5917 O O   . LYS E 5  176 ? -31.39680 -51.26021 46.59908  1.000 44.49240 ? 190 LYS E O   1 
ATOM   5918 C CB  . LYS E 5  176 ? -29.06955 -49.82845 45.25304  1.000 46.33451 ? 190 LYS E CB  1 
ATOM   5919 C CG  . LYS E 5  176 ? -28.28610 -49.63556 43.96668  1.000 42.25693 ? 190 LYS E CG  1 
ATOM   5920 C CD  . LYS E 5  176 ? -26.78928 -49.63617 44.23650  1.000 45.95269 ? 190 LYS E CD  1 
ATOM   5921 C CE  . LYS E 5  176 ? -26.00939 -49.10650 43.04588  1.000 47.67448 ? 190 LYS E CE  1 
ATOM   5922 N NZ  . LYS E 5  176 ? -24.54223 -49.08885 43.30461  1.000 61.90805 ? 190 LYS E NZ  1 
ATOM   5923 N N   . GLU E 5  177 ? -31.99564 -51.39591 44.42353  1.000 35.88754 ? 191 GLU E N   1 
ATOM   5924 C CA  . GLU E 5  177 ? -32.81143 -52.58619 44.63781  1.000 37.08290 ? 191 GLU E CA  1 
ATOM   5925 C C   . GLU E 5  177 ? -31.96353 -53.83397 44.85221  1.000 45.94624 ? 191 GLU E C   1 
ATOM   5926 O O   . GLU E 5  177 ? -32.40185 -54.76496 45.53715  1.000 48.83044 ? 191 GLU E O   1 
ATOM   5927 C CB  . GLU E 5  177 ? -33.76559 -52.78925 43.45968  1.000 42.24748 ? 191 GLU E CB  1 
ATOM   5928 C CG  . GLU E 5  177 ? -34.79845 -51.68124 43.31081  1.000 38.04763 ? 191 GLU E CG  1 
ATOM   5929 C CD  . GLU E 5  177 ? -35.93603 -52.05918 42.38304  1.000 33.28547 ? 191 GLU E CD  1 
ATOM   5930 O OE1 . GLU E 5  177 ? -35.73545 -52.93729 41.51848  1.000 44.06059 ? 191 GLU E OE1 1 
ATOM   5931 O OE2 . GLU E 5  177 ? -37.03234 -51.47622 42.51829  1.000 41.62751 ? 191 GLU E OE2 1 
ATOM   5932 N N   . GLN E 5  178 ? -30.76233 -53.87581 44.27822  1.000 47.28737 ? 192 GLN E N   1 
ATOM   5933 C CA  . GLN E 5  178 ? -29.82624 -54.97802 44.49185  1.000 49.87075 ? 192 GLN E CA  1 
ATOM   5934 C C   . GLN E 5  178 ? -28.45307 -54.37096 44.73126  1.000 50.89062 ? 192 GLN E C   1 
ATOM   5935 O O   . GLN E 5  178 ? -27.65395 -54.21672 43.79890  1.000 50.37166 ? 192 GLN E O   1 
ATOM   5936 C CB  . GLN E 5  178 ? -29.80829 -55.94172 43.30426  1.000 59.48380 ? 192 GLN E CB  1 
ATOM   5937 C CG  . GLN E 5  178 ? -31.08949 -56.75222 43.11713  1.000 59.68845 ? 192 GLN E CG  1 
ATOM   5938 C CD  . GLN E 5  178 ? -31.25669 -57.85592 44.14990  1.000 73.77011 ? 192 GLN E CD  1 
ATOM   5939 O OE1 . GLN E 5  178 ? -31.03966 -59.03148 43.85507  1.000 85.36791 ? 192 GLN E OE1 1 
ATOM   5940 N NE2 . GLN E 5  178 ? -31.66370 -57.48491 45.35943  1.000 68.74309 ? 192 GLN E NE2 1 
ATOM   5941 N N   . PRO E 5  179 ? -28.13948 -54.02110 45.98208  1.000 50.47268 ? 193 PRO E N   1 
ATOM   5942 C CA  . PRO E 5  179 ? -26.90724 -53.25781 46.25249  1.000 54.84837 ? 193 PRO E CA  1 
ATOM   5943 C C   . PRO E 5  179 ? -25.62986 -53.93626 45.78308  1.000 54.86694 ? 193 PRO E C   1 
ATOM   5944 O O   . PRO E 5  179 ? -24.59970 -53.26094 45.66842  1.000 56.60721 ? 193 PRO E O   1 
ATOM   5945 C CB  . PRO E 5  179 ? -26.92265 -53.10101 47.77995  1.000 45.38497 ? 193 PRO E CB  1 
ATOM   5946 C CG  . PRO E 5  179 ? -28.35906 -53.25209 48.16489  1.000 41.84951 ? 193 PRO E CG  1 
ATOM   5947 C CD  . PRO E 5  179 ? -28.93154 -54.24921 47.20211  1.000 44.00415 ? 193 PRO E CD  1 
ATOM   5948 N N   . ALA E 5  180 ? -25.65882 -55.24042 45.50268  1.000 56.06487 ? 194 ALA E N   1 
ATOM   5949 C CA  . ALA E 5  180 ? -24.44590 -55.93196 45.07747  1.000 60.94753 ? 194 ALA E CA  1 
ATOM   5950 C C   . ALA E 5  180 ? -24.04877 -55.53591 43.65960  1.000 66.96841 ? 194 ALA E C   1 
ATOM   5951 O O   . ALA E 5  180 ? -22.87285 -55.26824 43.38561  1.000 68.95723 ? 194 ALA E O   1 
ATOM   5952 C CB  . ALA E 5  180 ? -24.64242 -57.44461 45.17983  1.000 61.28134 ? 194 ALA E CB  1 
ATOM   5953 N N   . LEU E 5  181 ? -25.01514 -55.49027 42.74607  1.000 60.12430 ? 195 LEU E N   1 
ATOM   5954 C CA  . LEU E 5  181 ? -24.71096 -55.22864 41.34600  1.000 57.32688 ? 195 LEU E CA  1 
ATOM   5955 C C   . LEU E 5  181 ? -24.30936 -53.77385 41.13248  1.000 63.53906 ? 195 LEU E C   1 
ATOM   5956 O O   . LEU E 5  181 ? -24.85766 -52.86041 41.75607  1.000 60.53246 ? 195 LEU E O   1 
ATOM   5957 C CB  . LEU E 5  181 ? -25.91573 -55.56965 40.46988  1.000 60.30647 ? 195 LEU E CB  1 
ATOM   5958 C CG  . LEU E 5  181 ? -26.37310 -57.02897 40.47792  1.000 60.33837 ? 195 LEU E CG  1 
ATOM   5959 C CD1 . LEU E 5  181 ? -27.88353 -57.11672 40.32838  1.000 61.02101 ? 195 LEU E CD1 1 
ATOM   5960 C CD2 . LEU E 5  181 ? -25.67551 -57.81528 39.37974  1.000 68.01684 ? 195 LEU E CD2 1 
ATOM   5961 N N   . ASN E 5  182 ? -23.34016 -53.56383 40.23900  1.000 63.12069 ? 196 ASN E N   1 
ATOM   5962 C CA  . ASN E 5  182 ? -22.92435 -52.22105 39.85458  1.000 61.71452 ? 196 ASN E CA  1 
ATOM   5963 C C   . ASN E 5  182 ? -23.90966 -51.55056 38.90836  1.000 60.17893 ? 196 ASN E C   1 
ATOM   5964 O O   . ASN E 5  182 ? -23.80866 -50.33842 38.68884  1.000 59.70511 ? 196 ASN E O   1 
ATOM   5965 C CB  . ASN E 5  182 ? -21.53947 -52.26391 39.20272  1.000 64.20201 ? 196 ASN E CB  1 
ATOM   5966 N N   . ASP E 5  183 ? -24.85226 -52.30734 38.34876  1.000 58.30926 ? 197 ASP E N   1 
ATOM   5967 C CA  . ASP E 5  183 ? -25.85685 -51.79304 37.42722  1.000 53.47858 ? 197 ASP E CA  1 
ATOM   5968 C C   . ASP E 5  183 ? -27.26484 -52.01406 37.96937  1.000 47.75307 ? 197 ASP E C   1 
ATOM   5969 O O   . ASP E 5  183 ? -28.22069 -52.14768 37.20202  1.000 40.57610 ? 197 ASP E O   1 
ATOM   5970 C CB  . ASP E 5  183 ? -25.70593 -52.44644 36.05519  1.000 56.52673 ? 197 ASP E CB  1 
ATOM   5971 C CG  . ASP E 5  183 ? -25.66835 -53.96231 36.13575  1.000 62.00941 ? 197 ASP E CG  1 
ATOM   5972 O OD1 . ASP E 5  183 ? -25.64819 -54.50032 37.26403  1.000 52.49629 ? 197 ASP E OD1 1 
ATOM   5973 O OD2 . ASP E 5  183 ? -25.65796 -54.61653 35.07193  1.000 72.74978 ? 197 ASP E OD2 1 
ATOM   5974 N N   . SER E 5  184 ? -27.39896 -52.06413 39.29245  1.000 44.20597 ? 198 SER E N   1 
ATOM   5975 C CA  . SER E 5  184 ? -28.68468 -52.36243 39.90594  1.000 40.60561 ? 198 SER E CA  1 
ATOM   5976 C C   . SER E 5  184 ? -29.71387 -51.29582 39.56085  1.000 31.50148 ? 198 SER E C   1 
ATOM   5977 O O   . SER E 5  184 ? -29.39778 -50.10706 39.46601  1.000 34.00514 ? 198 SER E O   1 
ATOM   5978 C CB  . SER E 5  184 ? -28.53451 -52.46391 41.42187  1.000 46.12346 ? 198 SER E CB  1 
ATOM   5979 O OG  . SER E 5  184 ? -29.79907 -52.45432 42.06035  1.000 43.16452 ? 198 SER E OG  1 
ATOM   5980 N N   . ARG E 5  185 ? -30.95324 -51.73107 39.36645  1.000 30.64938 ? 199 ARG E N   1 
ATOM   5981 C CA  . ARG E 5  185 ? -32.04139 -50.79112 39.16883  1.000 35.04584 ? 199 ARG E CA  1 
ATOM   5982 C C   . ARG E 5  185 ? -32.40686 -50.13735 40.49905  1.000 37.77854 ? 199 ARG E C   1 
ATOM   5983 O O   . ARG E 5  185 ? -32.09433 -50.64742 41.57873  1.000 34.47158 ? 199 ARG E O   1 
ATOM   5984 C CB  . ARG E 5  185 ? -33.24059 -51.49983 38.54118  1.000 35.12581 ? 199 ARG E CB  1 
ATOM   5985 C CG  . ARG E 5  185 ? -32.92702 -52.04614 37.15089  1.000 39.06450 ? 199 ARG E CG  1 
ATOM   5986 C CD  . ARG E 5  185 ? -33.73122 -53.28927 36.81659  1.000 35.22865 ? 199 ARG E CD  1 
ATOM   5987 N NE  . ARG E 5  185 ? -35.11571 -52.97339 36.49109  1.000 44.25698 ? 199 ARG E NE  1 
ATOM   5988 C CZ  . ARG E 5  185 ? -35.91579 -53.76051 35.78533  1.000 44.19129 ? 199 ARG E CZ  1 
ATOM   5989 N NH1 . ARG E 5  185 ? -35.49549 -54.91866 35.30278  1.000 41.18599 ? 199 ARG E NH1 1 
ATOM   5990 N NH2 . ARG E 5  185 ? -37.16811 -53.37467 35.55585  1.000 37.07031 ? 199 ARG E NH2 1 
ATOM   5991 N N   . TYR E 5  186 ? -33.05875 -48.98311 40.41320  1.000 35.12885 ? 200 TYR E N   1 
ATOM   5992 C CA  . TYR E 5  186 ? -33.28132 -48.13443 41.57405  1.000 28.46522 ? 200 TYR E CA  1 
ATOM   5993 C C   . TYR E 5  186 ? -34.75493 -48.08769 41.95365  1.000 32.64382 ? 200 TYR E C   1 
ATOM   5994 O O   . TYR E 5  186 ? -35.64250 -48.48791 41.19473  1.000 30.31402 ? 200 TYR E O   1 
ATOM   5995 C CB  . TYR E 5  186 ? -32.76963 -46.71299 41.31720  1.000 30.03296 ? 200 TYR E CB  1 
ATOM   5996 C CG  . TYR E 5  186 ? -31.27441 -46.61468 41.14096  1.000 33.16422 ? 200 TYR E CG  1 
ATOM   5997 C CD1 . TYR E 5  186 ? -30.69409 -46.77190 39.89041  1.000 31.66832 ? 200 TYR E CD1 1 
ATOM   5998 C CD2 . TYR E 5  186 ? -30.44212 -46.35812 42.22361  1.000 33.55626 ? 200 TYR E CD2 1 
ATOM   5999 C CE1 . TYR E 5  186 ? -29.32714 -46.68125 39.72071  1.000 31.11609 ? 200 TYR E CE1 1 
ATOM   6000 C CE2 . TYR E 5  186 ? -29.07038 -46.26540 42.06338  1.000 35.45003 ? 200 TYR E CE2 1 
ATOM   6001 C CZ  . TYR E 5  186 ? -28.51981 -46.42803 40.80762  1.000 35.32859 ? 200 TYR E CZ  1 
ATOM   6002 O OH  . TYR E 5  186 ? -27.15798 -46.33780 40.63218  1.000 32.28163 ? 200 TYR E OH  1 
ATOM   6003 N N   . ALA E 5  187 ? -34.99618 -47.57821 43.15926  1.000 28.60987 ? 201 ALA E N   1 
ATOM   6004 C CA  . ALA E 5  187 ? -36.33576 -47.33514 43.66560  1.000 26.46268 ? 201 ALA E CA  1 
ATOM   6005 C C   . ALA E 5  187 ? -36.33396 -46.02411 44.43715  1.000 29.63693 ? 201 ALA E C   1 
ATOM   6006 O O   . ALA E 5  187 ? -35.30418 -45.59981 44.96758  1.000 27.54253 ? 201 ALA E O   1 
ATOM   6007 C CB  . ALA E 5  187 ? -36.82401 -48.48159 44.55856  1.000 26.73667 ? 201 ALA E CB  1 
ATOM   6008 N N   . LEU E 5  188 ? -37.49647 -45.38092 44.48688  1.000 21.75921 ? 202 LEU E N   1 
ATOM   6009 C CA  . LEU E 5  188 ? -37.63313 -44.09584 45.15394  1.000 20.42491 ? 202 LEU E CA  1 
ATOM   6010 C C   . LEU E 5  188 ? -39.04981 -43.97669 45.69372  1.000 25.32503 ? 202 LEU E C   1 
ATOM   6011 O O   . LEU E 5  188 ? -40.01181 -44.33279 45.00846  1.000 25.37168 ? 202 LEU E O   1 
ATOM   6012 C CB  . LEU E 5  188 ? -37.31941 -42.93911 44.19818  1.000 18.22231 ? 202 LEU E CB  1 
ATOM   6013 C CG  . LEU E 5  188 ? -37.57472 -41.51930 44.70671  1.000 27.74211 ? 202 LEU E CG  1 
ATOM   6014 C CD1 . LEU E 5  188 ? -36.44265 -41.06162 45.61238  1.000 24.99191 ? 202 LEU E CD1 1 
ATOM   6015 C CD2 . LEU E 5  188 ? -37.74787 -40.56160 43.53764  1.000 22.99110 ? 202 LEU E CD2 1 
ATOM   6016 N N   . SER E 5  189 ? -39.17131 -43.48316 46.92293  1.000 25.62315 ? 203 SER E N   1 
ATOM   6017 C CA  . SER E 5  189 ? -40.45938 -43.35236 47.58346  1.000 25.56132 ? 203 SER E CA  1 
ATOM   6018 C C   . SER E 5  189 ? -40.70956 -41.90105 47.96559  1.000 27.91446 ? 203 SER E C   1 
ATOM   6019 O O   . SER E 5  189 ? -39.77877 -41.14729 48.26576  1.000 24.81311 ? 203 SER E O   1 
ATOM   6020 C CB  . SER E 5  189 ? -40.53957 -44.23389 48.83686  1.000 25.57385 ? 203 SER E CB  1 
ATOM   6021 O OG  . SER E 5  189 ? -40.10965 -43.52376 49.98320  1.000 29.20897 ? 203 SER E OG  1 
ATOM   6022 N N   . SER E 5  190 ? -41.98348 -41.52110 47.94838  1.000 21.53031 ? 204 SER E N   1 
ATOM   6023 C CA  . SER E 5  190 ? -42.41929 -40.20463 48.38254  1.000 22.00584 ? 204 SER E CA  1 
ATOM   6024 C C   . SER E 5  190 ? -43.74451 -40.35700 49.10979  1.000 26.18385 ? 204 SER E C   1 
ATOM   6025 O O   . SER E 5  190 ? -44.45601 -41.35090 48.94337  1.000 24.29299 ? 204 SER E O   1 
ATOM   6026 C CB  . SER E 5  190 ? -42.56197 -39.23478 47.20364  1.000 21.19086 ? 204 SER E CB  1 
ATOM   6027 O OG  . SER E 5  190 ? -42.94512 -37.93979 47.63499  1.000 21.08051 ? 204 SER E OG  1 
ATOM   6028 N N   . ARG E 5  191 ? -44.07278 -39.36399 49.92803  1.000 20.91770 ? 205 ARG E N   1 
ATOM   6029 C CA  . ARG E 5  191 ? -45.31561 -39.40786 50.67731  1.000 25.01940 ? 205 ARG E CA  1 
ATOM   6030 C C   . ARG E 5  191 ? -45.95963 -38.02882 50.66443  1.000 25.43701 ? 205 ARG E C   1 
ATOM   6031 O O   . ARG E 5  191 ? -45.27379 -37.00376 50.63665  1.000 26.82712 ? 205 ARG E O   1 
ATOM   6032 C CB  . ARG E 5  191 ? -45.08743 -39.92825 52.11497  1.000 24.80259 ? 205 ARG E CB  1 
ATOM   6033 C CG  . ARG E 5  191 ? -44.33272 -39.00180 53.05502  1.000 31.43672 ? 205 ARG E CG  1 
ATOM   6034 C CD  . ARG E 5  191 ? -42.81271 -39.15704 52.98289  1.000 33.01460 ? 205 ARG E CD  1 
ATOM   6035 N NE  . ARG E 5  191 ? -42.29446 -40.48187 53.30608  1.000 35.84850 ? 205 ARG E NE  1 
ATOM   6036 C CZ  . ARG E 5  191 ? -41.21190 -41.01076 52.74784  1.000 43.11279 ? 205 ARG E CZ  1 
ATOM   6037 N NH1 . ARG E 5  191 ? -40.54444 -40.37768 51.79618  1.000 34.30927 ? 205 ARG E NH1 1 
ATOM   6038 N NH2 . ARG E 5  191 ? -40.77927 -42.19766 53.16341  1.000 48.78749 ? 205 ARG E NH2 1 
ATOM   6039 N N   . LEU E 5  192 ? -47.29206 -38.02069 50.63863  1.000 24.05283 ? 206 LEU E N   1 
ATOM   6040 C CA  . LEU E 5  192 ? -48.08688 -36.79800 50.66318  1.000 23.75981 ? 206 LEU E CA  1 
ATOM   6041 C C   . LEU E 5  192 ? -49.17226 -36.95887 51.71584  1.000 23.10517 ? 206 LEU E C   1 
ATOM   6042 O O   . LEU E 5  192 ? -49.99697 -37.87426 51.62278  1.000 22.28432 ? 206 LEU E O   1 
ATOM   6043 C CB  . LEU E 5  192 ? -48.70406 -36.50735 49.29041  1.000 21.35688 ? 206 LEU E CB  1 
ATOM   6044 C CG  . LEU E 5  192 ? -49.89611 -35.54494 49.25631  1.000 22.49956 ? 206 LEU E CG  1 
ATOM   6045 C CD1 . LEU E 5  192 ? -49.49814 -34.14882 49.71755  1.000 25.34823 ? 206 LEU E CD1 1 
ATOM   6046 C CD2 . LEU E 5  192 ? -50.51490 -35.49468 47.86823  1.000 22.76215 ? 206 LEU E CD2 1 
ATOM   6047 N N   . ARG E 5  193 ? -49.17385 -36.07706 52.71147  1.000 22.77368 ? 207 ARG E N   1 
ATOM   6048 C CA  . ARG E 5  193 ? -50.11645 -36.14981 53.82052  1.000 26.73692 ? 207 ARG E CA  1 
ATOM   6049 C C   . ARG E 5  193 ? -51.09592 -34.98630 53.74999  1.000 25.32630 ? 207 ARG E C   1 
ATOM   6050 O O   . ARG E 5  193 ? -50.68521 -33.82387 53.66089  1.000 23.66189 ? 207 ARG E O   1 
ATOM   6051 C CB  . ARG E 5  193 ? -49.38778 -36.14658 55.16750  1.000 18.40657 ? 207 ARG E CB  1 
ATOM   6052 C CG  . ARG E 5  193 ? -50.25977 -36.60180 56.33032  1.000 20.79674 ? 207 ARG E CG  1 
ATOM   6053 C CD  . ARG E 5  193 ? -49.44454 -36.85018 57.59217  1.000 24.94740 ? 207 ARG E CD  1 
ATOM   6054 N NE  . ARG E 5  193 ? -50.07150 -37.84609 58.45310  1.000 21.64424 ? 207 ARG E NE  1 
ATOM   6055 C CZ  . ARG E 5  193 ? -49.61204 -38.20629 59.64358  1.000 27.26670 ? 207 ARG E CZ  1 
ATOM   6056 N NH1 . ARG E 5  193 ? -48.50996 -37.67610 60.14866  1.000 21.80814 ? 207 ARG E NH1 1 
ATOM   6057 N NH2 . ARG E 5  193 ? -50.27610 -39.12066 60.34598  1.000 24.00856 ? 207 ARG E NH2 1 
ATOM   6058 N N   . VAL E 5  194 ? -52.38934 -35.30561 53.78678  1.000 24.27248 ? 208 VAL E N   1 
ATOM   6059 C CA  . VAL E 5  194 ? -53.45414 -34.31413 53.81370  1.000 26.20982 ? 208 VAL E CA  1 
ATOM   6060 C C   . VAL E 5  194 ? -54.37551 -34.63826 54.98226  1.000 24.91693 ? 208 VAL E C   1 
ATOM   6061 O O   . VAL E 5  194 ? -54.29229 -35.70464 55.59234  1.000 25.85835 ? 208 VAL E O   1 
ATOM   6062 C CB  . VAL E 5  194 ? -54.25281 -34.26688 52.49368  1.000 24.98040 ? 208 VAL E CB  1 
ATOM   6063 C CG1 . VAL E 5  194 ? -53.32510 -34.02413 51.31390  1.000 23.07749 ? 208 VAL E CG1 1 
ATOM   6064 C CG2 . VAL E 5  194 ? -55.04262 -35.55397 52.30651  1.000 21.75338 ? 208 VAL E CG2 1 
ATOM   6065 N N   . SER E 5  195 ? -55.25989 -33.69513 55.29214  1.000 29.35093 ? 209 SER E N   1 
ATOM   6066 C CA  . SER E 5  195 ? -56.27232 -33.93835 56.30800  1.000 33.28172 ? 209 SER E CA  1 
ATOM   6067 C C   . SER E 5  195 ? -57.24354 -35.01366 55.83483  1.000 28.13012 ? 209 SER E C   1 
ATOM   6068 O O   . SER E 5  195 ? -57.43404 -35.22530 54.63406  1.000 29.38386 ? 209 SER E O   1 
ATOM   6069 C CB  . SER E 5  195 ? -57.03086 -32.65065 56.63063  1.000 31.92405 ? 209 SER E CB  1 
ATOM   6070 O OG  . SER E 5  195 ? -57.86083 -32.26299 55.54936  1.000 30.92457 ? 209 SER E OG  1 
ATOM   6071 N N   . ALA E 5  196 ? -57.85158 -35.70868 56.79850  1.000 29.99735 ? 210 ALA E N   1 
ATOM   6072 C CA  . ALA E 5  196 ? -58.84987 -36.71754 56.45702  1.000 32.18213 ? 210 ALA E CA  1 
ATOM   6073 C C   . ALA E 5  196 ? -60.01700 -36.09932 55.69819  1.000 30.07638 ? 210 ALA E C   1 
ATOM   6074 O O   . ALA E 5  196 ? -60.57578 -36.72257 54.78788  1.000 31.61061 ? 210 ALA E O   1 
ATOM   6075 C CB  . ALA E 5  196 ? -59.34199 -37.42126 57.72158  1.000 30.59483 ? 210 ALA E CB  1 
ATOM   6076 N N   . THR E 5  197 ? -60.39202 -34.86824 56.05477  1.000 34.11454 ? 211 THR E N   1 
ATOM   6077 C CA  . THR E 5  197 ? -61.47789 -34.18334 55.35933  1.000 33.41272 ? 211 THR E CA  1 
ATOM   6078 C C   . THR E 5  197 ? -61.12946 -33.95135 53.89317  1.000 33.17794 ? 211 THR E C   1 
ATOM   6079 O O   . THR E 5  197 ? -61.95103 -34.19355 53.00055  1.000 32.91674 ? 211 THR E O   1 
ATOM   6080 C CB  . THR E 5  197 ? -61.78878 -32.85842 56.05982  1.000 39.14220 ? 211 THR E CB  1 
ATOM   6081 O OG1 . THR E 5  197 ? -62.55780 -33.11076 57.24248  1.000 49.06700 ? 211 THR E OG1 1 
ATOM   6082 C CG2 . THR E 5  197 ? -62.57297 -31.93082 55.14184  1.000 42.82105 ? 211 THR E CG2 1 
ATOM   6083 N N   . PHE E 5  198 ? -59.90624 -33.48608 53.62575  1.000 28.06509 ? 212 PHE E N   1 
ATOM   6084 C CA  . PHE E 5  198 ? -59.48187 -33.26956 52.24596  1.000 29.43753 ? 212 PHE E CA  1 
ATOM   6085 C C   . PHE E 5  198 ? -59.47126 -34.57432 51.46007  1.000 26.56792 ? 212 PHE E C   1 
ATOM   6086 O O   . PHE E 5  198 ? -59.87533 -34.60779 50.29183  1.000 32.62824 ? 212 PHE E O   1 
ATOM   6087 C CB  . PHE E 5  198 ? -58.09947 -32.61691 52.21862  1.000 34.53232 ? 212 PHE E CB  1 
ATOM   6088 C CG  . PHE E 5  198 ? -57.74030 -32.01020 50.89145  1.000 33.64465 ? 212 PHE E CG  1 
ATOM   6089 C CD1 . PHE E 5  198 ? -58.08961 -30.70304 50.59446  1.000 33.26177 ? 212 PHE E CD1 1 
ATOM   6090 C CD2 . PHE E 5  198 ? -57.05346 -32.74816 49.94032  1.000 28.29253 ? 212 PHE E CD2 1 
ATOM   6091 C CE1 . PHE E 5  198 ? -57.76054 -30.14272 49.37231  1.000 34.28090 ? 212 PHE E CE1 1 
ATOM   6092 C CE2 . PHE E 5  198 ? -56.72151 -32.19417 48.71704  1.000 30.57758 ? 212 PHE E CE2 1 
ATOM   6093 C CZ  . PHE E 5  198 ? -57.07522 -30.88988 48.43296  1.000 33.09423 ? 212 PHE E CZ  1 
ATOM   6094 N N   . TRP E 5  199 ? -59.01780 -35.66229 52.08659  1.000 26.78141 ? 213 TRP E N   1 
ATOM   6095 C CA  . TRP E 5  199 ? -58.96286 -36.94550 51.39428  1.000 28.05161 ? 213 TRP E CA  1 
ATOM   6096 C C   . TRP E 5  199 ? -60.35126 -37.53931 51.18627  1.000 29.45579 ? 213 TRP E C   1 
ATOM   6097 O O   . TRP E 5  199 ? -60.56928 -38.27649 50.21850  1.000 27.18374 ? 213 TRP E O   1 
ATOM   6098 C CB  . TRP E 5  199 ? -58.07837 -37.92017 52.17192  1.000 21.92088 ? 213 TRP E CB  1 
ATOM   6099 C CG  . TRP E 5  199 ? -58.24622 -39.35422 51.76421  1.000 20.57957 ? 213 TRP E CG  1 
ATOM   6100 C CD1 . TRP E 5  199 ? -58.77716 -40.36215 52.51511  1.000 20.55732 ? 213 TRP E CD1 1 
ATOM   6101 C CD2 . TRP E 5  199 ? -57.87691 -39.94067 50.50956  1.000 22.14940 ? 213 TRP E CD2 1 
ATOM   6102 N NE1 . TRP E 5  199 ? -58.76136 -41.53930 51.80711  1.000 24.35141 ? 213 TRP E NE1 1 
ATOM   6103 C CE2 . TRP E 5  199 ? -58.21557 -41.30727 50.57197  1.000 29.30979 ? 213 TRP E CE2 1 
ATOM   6104 C CE3 . TRP E 5  199 ? -57.29660 -39.44245 49.33891  1.000 25.61861 ? 213 TRP E CE3 1 
ATOM   6105 C CZ2 . TRP E 5  199 ? -57.99400 -42.18125 49.50882  1.000 26.68579 ? 213 TRP E CZ2 1 
ATOM   6106 C CZ3 . TRP E 5  199 ? -57.07547 -40.31244 48.28512  1.000 30.78636 ? 213 TRP E CZ3 1 
ATOM   6107 C CH2 . TRP E 5  199 ? -57.42352 -41.66617 48.37778  1.000 29.21330 ? 213 TRP E CH2 1 
ATOM   6108 N N   . GLN E 5  200 ? -61.29865 -37.23698 52.07049  1.000 29.10703 ? 214 GLN E N   1 
ATOM   6109 C CA  . GLN E 5  200 ? -62.63880 -37.79605 51.94708  1.000 37.30396 ? 214 GLN E CA  1 
ATOM   6110 C C   . GLN E 5  200 ? -63.51897 -37.02538 50.97018  1.000 35.05752 ? 214 GLN E C   1 
ATOM   6111 O O   . GLN E 5  200 ? -64.65591 -37.44339 50.72522  1.000 34.45403 ? 214 GLN E O   1 
ATOM   6112 C CB  . GLN E 5  200 ? -63.30615 -37.86327 53.32376  1.000 29.20914 ? 214 GLN E CB  1 
ATOM   6113 C CG  . GLN E 5  200 ? -62.90725 -39.09727 54.12304  1.000 28.57198 ? 214 GLN E CG  1 
ATOM   6114 C CD  . GLN E 5  200 ? -62.94324 -38.86886 55.62041  1.000 38.36261 ? 214 GLN E CD  1 
ATOM   6115 O OE1 . GLN E 5  200 ? -63.08664 -37.73822 56.08477  1.000 36.53649 ? 214 GLN E OE1 1 
ATOM   6116 N NE2 . GLN E 5  200 ? -62.80415 -39.94538 56.38615  1.000 33.02499 ? 214 GLN E NE2 1 
ATOM   6117 N N   . ASN E 5  201 ? -63.02528 -35.92374 50.40801  1.000 29.63534 ? 215 ASN E N   1 
ATOM   6118 C CA  . ASN E 5  201 ? -63.74181 -35.17200 49.38666  1.000 32.23076 ? 215 ASN E CA  1 
ATOM   6119 C C   . ASN E 5  201 ? -63.63488 -35.91269 48.05831  1.000 34.53719 ? 215 ASN E C   1 
ATOM   6120 O O   . ASN E 5  201 ? -62.53926 -36.01684 47.49213  1.000 34.27957 ? 215 ASN E O   1 
ATOM   6121 C CB  . ASN E 5  201 ? -63.17768 -33.75346 49.27377  1.000 30.21569 ? 215 ASN E CB  1 
ATOM   6122 C CG  . ASN E 5  201 ? -64.01321 -32.85370 48.37941  1.000 34.97222 ? 215 ASN E CG  1 
ATOM   6123 O OD1 . ASN E 5  201 ? -64.91536 -33.31093 47.67817  1.000 43.92555 ? 215 ASN E OD1 1 
ATOM   6124 N ND2 . ASN E 5  201 ? -63.71048 -31.56073 48.40060  1.000 43.09341 ? 215 ASN E ND2 1 
ATOM   6125 N N   . PRO E 5  202 ? -64.74583 -36.43397 47.52667  1.000 40.69969 ? 216 PRO E N   1 
ATOM   6126 C CA  . PRO E 5  202 ? -64.66937 -37.24992 46.30293  1.000 34.08386 ? 216 PRO E CA  1 
ATOM   6127 C C   . PRO E 5  202 ? -64.24593 -36.47890 45.06415  1.000 32.91064 ? 216 PRO E C   1 
ATOM   6128 O O   . PRO E 5  202 ? -63.93435 -37.11132 44.04556  1.000 30.08709 ? 216 PRO E O   1 
ATOM   6129 C CB  . PRO E 5  202 ? -66.09784 -37.78845 46.15259  1.000 37.38452 ? 216 PRO E CB  1 
ATOM   6130 C CG  . PRO E 5  202 ? -66.95057 -36.78964 46.86675  1.000 39.39987 ? 216 PRO E CG  1 
ATOM   6131 C CD  . PRO E 5  202 ? -66.12555 -36.31734 48.03026  1.000 35.75458 ? 216 PRO E CD  1 
ATOM   6132 N N   . ARG E 5  203 ? -64.22098 -35.15021 45.11053  1.000 27.99412 ? 217 ARG E N   1 
ATOM   6133 C CA  . ARG E 5  203 ? -63.84155 -34.34710 43.95705  1.000 38.70497 ? 217 ARG E CA  1 
ATOM   6134 C C   . ARG E 5  203 ? -62.36582 -33.96595 43.95199  1.000 38.62616 ? 217 ARG E C   1 
ATOM   6135 O O   . ARG E 5  203 ? -61.91634 -33.30527 43.01027  1.000 37.05315 ? 217 ARG E O   1 
ATOM   6136 C CB  . ARG E 5  203 ? -64.70586 -33.08428 43.89435  1.000 42.37391 ? 217 ARG E CB  1 
ATOM   6137 C CG  . ARG E 5  203 ? -66.14177 -33.35769 43.47358  1.000 49.91720 ? 217 ARG E CG  1 
ATOM   6138 C CD  . ARG E 5  203 ? -66.84739 -32.09224 43.03047  1.000 42.62626 ? 217 ARG E CD  1 
ATOM   6139 N NE  . ARG E 5  203 ? -68.29513 -32.26020 43.01971  1.000 45.81204 ? 217 ARG E NE  1 
ATOM   6140 C CZ  . ARG E 5  203 ? -69.16128 -31.27139 42.84750  1.000 54.71834 ? 217 ARG E CZ  1 
ATOM   6141 N NH1 . ARG E 5  203 ? -68.75891 -30.02255 42.67696  1.000 57.16740 ? 217 ARG E NH1 1 
ATOM   6142 N NH2 . ARG E 5  203 ? -70.46360 -31.54265 42.84298  1.000 44.86933 ? 217 ARG E NH2 1 
ATOM   6143 N N   . ASN E 5  204 ? -61.60484 -34.36222 44.96876  1.000 31.22459 ? 218 ASN E N   1 
ATOM   6144 C CA  . ASN E 5  204 ? -60.17901 -34.06944 45.02689  1.000 35.87305 ? 218 ASN E CA  1 
ATOM   6145 C C   . ASN E 5  204 ? -59.40482 -35.14197 44.27051  1.000 30.32007 ? 218 ASN E C   1 
ATOM   6146 O O   . ASN E 5  204 ? -59.62555 -36.33986 44.48013  1.000 26.00555 ? 218 ASN E O   1 
ATOM   6147 C CB  . ASN E 5  204 ? -59.70245 -33.98943 46.47807  1.000 27.67418 ? 218 ASN E CB  1 
ATOM   6148 C CG  . ASN E 5  204 ? -59.97380 -32.63572 47.10770  1.000 30.94367 ? 218 ASN E CG  1 
ATOM   6149 O OD1 . ASN E 5  204 ? -60.05434 -31.62028 46.41516  1.000 30.02617 ? 218 ASN E OD1 1 
ATOM   6150 N ND2 . ASN E 5  204 ? -60.11402 -32.61470 48.42947  1.000 33.62977 ? 218 ASN E ND2 1 
ATOM   6151 N N   . HIS E 5  205 ? -58.50030 -34.70842 43.39391  1.000 28.09321 ? 219 HIS E N   1 
ATOM   6152 C CA  . HIS E 5  205 ? -57.71833 -35.60351 42.55062  1.000 29.40726 ? 219 HIS E CA  1 
ATOM   6153 C C   . HIS E 5  205 ? -56.24270 -35.48960 42.90954  1.000 30.52724 ? 219 HIS E C   1 
ATOM   6154 O O   . HIS E 5  205 ? -55.71842 -34.38049 43.05774  1.000 28.47060 ? 219 HIS E O   1 
ATOM   6155 C CB  . HIS E 5  205 ? -57.93153 -35.28389 41.06767  1.000 27.30835 ? 219 HIS E CB  1 
ATOM   6156 C CG  . HIS E 5  205 ? -57.15000 -36.16339 40.14269  1.000 34.12128 ? 219 HIS E CG  1 
ATOM   6157 N ND1 . HIS E 5  205 ? -55.98794 -35.75017 39.52688  1.000 36.69449 ? 219 HIS E ND1 1 
ATOM   6158 C CD2 . HIS E 5  205 ? -57.36241 -37.43556 39.73035  1.000 33.73441 ? 219 HIS E CD2 1 
ATOM   6159 C CE1 . HIS E 5  205 ? -55.51880 -36.72953 38.77442  1.000 39.90594 ? 219 HIS E CE1 1 
ATOM   6160 N NE2 . HIS E 5  205 ? -56.33433 -37.76334 38.87989  1.000 40.38716 ? 219 HIS E NE2 1 
ATOM   6161 N N   . PHE E 5  206 ? -55.57733 -36.63553 43.03584  1.000 24.25136 ? 220 PHE E N   1 
ATOM   6162 C CA  . PHE E 5  206 ? -54.17750 -36.70986 43.43024  1.000 27.24660 ? 220 PHE E CA  1 
ATOM   6163 C C   . PHE E 5  206 ? -53.39284 -37.46218 42.36562  1.000 28.78249 ? 220 PHE E C   1 
ATOM   6164 O O   . PHE E 5  206 ? -53.85301 -38.48967 41.86139  1.000 29.21941 ? 220 PHE E O   1 
ATOM   6165 C CB  . PHE E 5  206 ? -54.01390 -37.42024 44.78406  1.000 28.59821 ? 220 PHE E CB  1 
ATOM   6166 C CG  . PHE E 5  206 ? -54.87460 -36.85670 45.88405  1.000 26.27916 ? 220 PHE E CG  1 
ATOM   6167 C CD1 . PHE E 5  206 ? -56.22307 -37.17492 45.96649  1.000 30.59931 ? 220 PHE E CD1 1 
ATOM   6168 C CD2 . PHE E 5  206 ? -54.32941 -36.02330 46.84672  1.000 25.98700 ? 220 PHE E CD2 1 
ATOM   6169 C CE1 . PHE E 5  206 ? -57.01192 -36.66019 46.97848  1.000 31.02264 ? 220 PHE E CE1 1 
ATOM   6170 C CE2 . PHE E 5  206 ? -55.11262 -35.50728 47.86348  1.000 26.57576 ? 220 PHE E CE2 1 
ATOM   6171 C CZ  . PHE E 5  206 ? -56.45540 -35.82613 47.92968  1.000 30.28176 ? 220 PHE E CZ  1 
ATOM   6172 N N   . ARG E 5  207 ? -52.20452 -36.95917 42.02991  1.000 22.37606 ? 221 ARG E N   1 
ATOM   6173 C CA  . ARG E 5  207 ? -51.36325 -37.59857 41.02395  1.000 27.27109 ? 221 ARG E CA  1 
ATOM   6174 C C   . ARG E 5  207 ? -49.90031 -37.52603 41.43499  1.000 24.97660 ? 221 ARG E C   1 
ATOM   6175 O O   . ARG E 5  207 ? -49.40091 -36.45013 41.77697  1.000 21.88207 ? 221 ARG E O   1 
ATOM   6176 C CB  . ARG E 5  207 ? -51.54685 -36.94839 39.64473  1.000 22.85777 ? 221 ARG E CB  1 
ATOM   6177 C CG  . ARG E 5  207 ? -50.74147 -37.62076 38.53547  1.000 26.61893 ? 221 ARG E CG  1 
ATOM   6178 C CD  . ARG E 5  207 ? -51.11010 -37.09214 37.14960  1.000 30.50780 ? 221 ARG E CD  1 
ATOM   6179 N NE  . ARG E 5  207 ? -50.77943 -35.68093 36.98570  1.000 31.78891 ? 221 ARG E NE  1 
ATOM   6180 C CZ  . ARG E 5  207 ? -49.66364 -35.23390 36.42371  1.000 41.28928 ? 221 ARG E CZ  1 
ATOM   6181 N NH1 . ARG E 5  207 ? -48.74178 -36.06305 35.96122  1.000 37.84218 ? 221 ARG E NH1 1 
ATOM   6182 N NH2 . ARG E 5  207 ? -49.46525 -33.92199 36.32707  1.000 38.24785 ? 221 ARG E NH2 1 
ATOM   6183 N N   . CYS E 5  208 ? -49.22225 -38.67121 41.39867  1.000 23.24464 ? 222 CYS E N   1 
ATOM   6184 C CA  . CYS E 5  208 ? -47.77334 -38.74054 41.53921  1.000 27.30950 ? 222 CYS E CA  1 
ATOM   6185 C C   . CYS E 5  208 ? -47.15443 -38.85031 40.15217  1.000 27.00057 ? 222 CYS E C   1 
ATOM   6186 O O   . CYS E 5  208 ? -47.50715 -39.74905 39.38230  1.000 29.17313 ? 222 CYS E O   1 
ATOM   6187 C CB  . CYS E 5  208 ? -47.35203 -39.93348 42.40030  1.000 18.03351 ? 222 CYS E CB  1 
ATOM   6188 S SG  . CYS E 5  208 ? -45.55988 -40.17720 42.48152  1.000 40.31604 ? 222 CYS E SG  1 
ATOM   6189 N N   . GLN E 5  209 ? -46.23587 -37.94034 39.83816  1.000 25.16804 ? 223 GLN E N   1 
ATOM   6190 C CA  . GLN E 5  209 ? -45.64320 -37.83989 38.51081  1.000 24.06185 ? 223 GLN E CA  1 
ATOM   6191 C C   . GLN E 5  209 ? -44.13599 -38.02712 38.60338  1.000 30.66435 ? 223 GLN E C   1 
ATOM   6192 O O   . GLN E 5  209 ? -43.46557 -37.32732 39.36954  1.000 30.47611 ? 223 GLN E O   1 
ATOM   6193 C CB  . GLN E 5  209 ? -45.97085 -36.48759 37.87413  1.000 27.80608 ? 223 GLN E CB  1 
ATOM   6194 C CG  . GLN E 5  209 ? -45.24597 -36.21626 36.57158  1.000 32.86847 ? 223 GLN E CG  1 
ATOM   6195 C CD  . GLN E 5  209 ? -45.54030 -34.83327 36.02504  1.000 39.99382 ? 223 GLN E CD  1 
ATOM   6196 O OE1 . GLN E 5  209 ? -46.68478 -34.51210 35.70178  1.000 35.48790 ? 223 GLN E OE1 1 
ATOM   6197 N NE2 . GLN E 5  209 ? -44.50594 -34.00569 35.91797  1.000 34.82317 ? 223 GLN E NE2 1 
ATOM   6198 N N   . VAL E 5  210 ? -43.60670 -38.96291 37.81995  1.000 24.07022 ? 224 VAL E N   1 
ATOM   6199 C CA  . VAL E 5  210 ? -42.17790 -39.25621 37.79001  1.000 24.38189 ? 224 VAL E CA  1 
ATOM   6200 C C   . VAL E 5  210 ? -41.67522 -39.00058 36.37642  1.000 28.18728 ? 224 VAL E C   1 
ATOM   6201 O O   . VAL E 5  210 ? -41.95076 -39.78441 35.45821  1.000 24.45013 ? 224 VAL E O   1 
ATOM   6202 C CB  . VAL E 5  210 ? -41.87227 -40.69405 38.22831  1.000 21.72908 ? 224 VAL E CB  1 
ATOM   6203 C CG1 . VAL E 5  210 ? -40.37014 -40.92435 38.26232  1.000 27.70206 ? 224 VAL E CG1 1 
ATOM   6204 C CG2 . VAL E 5  210 ? -42.48437 -40.97255 39.59037  1.000 25.97187 ? 224 VAL E CG2 1 
ATOM   6205 N N   . GLN E 5  211 ? -40.94242 -37.90632 36.19721  1.000 27.76766 ? 225 GLN E N   1 
ATOM   6206 C CA  . GLN E 5  211 ? -40.26640 -37.64643 34.93469  1.000 28.62327 ? 225 GLN E CA  1 
ATOM   6207 C C   . GLN E 5  211 ? -38.99559 -38.48340 34.87556  1.000 30.60248 ? 225 GLN E C   1 
ATOM   6208 O O   . GLN E 5  211 ? -38.15026 -38.40102 35.77258  1.000 26.53078 ? 225 GLN E O   1 
ATOM   6209 C CB  . GLN E 5  211 ? -39.94267 -36.16187 34.78900  1.000 25.90780 ? 225 GLN E CB  1 
ATOM   6210 C CG  . GLN E 5  211 ? -39.03210 -35.84812 33.61195  1.000 24.93400 ? 225 GLN E CG  1 
ATOM   6211 C CD  . GLN E 5  211 ? -39.76789 -35.86906 32.28625  1.000 30.87499 ? 225 GLN E CD  1 
ATOM   6212 O OE1 . GLN E 5  211 ? -40.65084 -35.04776 32.04128  1.000 27.74410 ? 225 GLN E OE1 1 
ATOM   6213 N NE2 . GLN E 5  211 ? -39.41024 -36.81437 31.42473  1.000 24.21654 ? 225 GLN E NE2 1 
ATOM   6214 N N   . PHE E 5  212 ? -38.86779 -39.29583 33.83198  1.000 26.77901 ? 226 PHE E N   1 
ATOM   6215 C CA  . PHE E 5  212 ? -37.70209 -40.14100 33.62573  1.000 21.10651 ? 226 PHE E CA  1 
ATOM   6216 C C   . PHE E 5  212 ? -36.93064 -39.64297 32.41370  1.000 29.27019 ? 226 PHE E C   1 
ATOM   6217 O O   . PHE E 5  212 ? -37.52383 -39.32245 31.37947  1.000 28.74964 ? 226 PHE E O   1 
ATOM   6218 C CB  . PHE E 5  212 ? -38.11351 -41.60355 33.42894  1.000 21.44553 ? 226 PHE E CB  1 
ATOM   6219 C CG  . PHE E 5  212 ? -36.97972 -42.51381 33.04137  1.000 25.20740 ? 226 PHE E CG  1 
ATOM   6220 C CD1 . PHE E 5  212 ? -35.98248 -42.82968 33.94968  1.000 21.93815 ? 226 PHE E CD1 1 
ATOM   6221 C CD2 . PHE E 5  212 ? -36.92020 -43.06472 31.77015  1.000 26.83723 ? 226 PHE E CD2 1 
ATOM   6222 C CE1 . PHE E 5  212 ? -34.94343 -43.67187 33.59712  1.000 23.27183 ? 226 PHE E CE1 1 
ATOM   6223 C CE2 . PHE E 5  212 ? -35.88249 -43.90619 31.40965  1.000 27.57370 ? 226 PHE E CE2 1 
ATOM   6224 C CZ  . PHE E 5  212 ? -34.89274 -44.21109 32.32524  1.000 28.57180 ? 226 PHE E CZ  1 
ATOM   6225 N N   . TYR E 5  213 ? -35.61056 -39.56239 32.54990  1.000 25.59121 ? 227 TYR E N   1 
ATOM   6226 C CA  . TYR E 5  213 ? -34.72862 -39.14938 31.46352  1.000 29.05028 ? 227 TYR E CA  1 
ATOM   6227 C C   . TYR E 5  213 ? -33.97198 -40.38195 30.98655  1.000 27.25867 ? 227 TYR E C   1 
ATOM   6228 O O   . TYR E 5  213 ? -33.14593 -40.93326 31.72107  1.000 27.32665 ? 227 TYR E O   1 
ATOM   6229 C CB  . TYR E 5  213 ? -33.77650 -38.04475 31.91694  1.000 27.98700 ? 227 TYR E CB  1 
ATOM   6230 C CG  . TYR E 5  213 ? -34.48291 -36.77606 32.34240  1.000 31.32009 ? 227 TYR E CG  1 
ATOM   6231 C CD1 . TYR E 5  213 ? -34.78223 -35.78072 31.41941  1.000 28.74984 ? 227 TYR E CD1 1 
ATOM   6232 C CD2 . TYR E 5  213 ? -34.85599 -36.57595 33.66666  1.000 32.00034 ? 227 TYR E CD2 1 
ATOM   6233 C CE1 . TYR E 5  213 ? -35.43116 -34.61982 31.80469  1.000 30.25710 ? 227 TYR E CE1 1 
ATOM   6234 C CE2 . TYR E 5  213 ? -35.50560 -35.41954 34.06080  1.000 28.31582 ? 227 TYR E CE2 1 
ATOM   6235 C CZ  . TYR E 5  213 ? -35.78937 -34.44544 33.12655  1.000 31.92251 ? 227 TYR E CZ  1 
ATOM   6236 O OH  . TYR E 5  213 ? -36.43347 -33.29367 33.51580  1.000 38.89739 ? 227 TYR E OH  1 
ATOM   6237 N N   . GLY E 5  214 ? -34.26597 -40.82014 29.76568  1.000 28.90995 ? 228 GLY E N   1 
ATOM   6238 C CA  . GLY E 5  214 ? -33.67292 -42.03454 29.24459  1.000 29.08839 ? 228 GLY E CA  1 
ATOM   6239 C C   . GLY E 5  214 ? -33.00458 -41.85607 27.89869  1.000 36.40997 ? 228 GLY E C   1 
ATOM   6240 O O   . GLY E 5  214 ? -32.23892 -40.90860 27.69704  1.000 35.77657 ? 228 GLY E O   1 
ATOM   6241 N N   . LEU E 5  215 ? -33.29075 -42.76244 26.96912  1.000 35.80862 ? 229 LEU E N   1 
ATOM   6242 C CA  . LEU E 5  215 ? -32.65689 -42.73614 25.66082  1.000 43.58966 ? 229 LEU E CA  1 
ATOM   6243 C C   . LEU E 5  215 ? -33.32966 -41.72069 24.74583  1.000 45.60583 ? 229 LEU E C   1 
ATOM   6244 O O   . LEU E 5  215 ? -34.50715 -41.38535 24.90594  1.000 42.28626 ? 229 LEU E O   1 
ATOM   6245 C CB  . LEU E 5  215 ? -32.70107 -44.11983 25.01219  1.000 40.56440 ? 229 LEU E CB  1 
ATOM   6246 C CG  . LEU E 5  215 ? -32.19260 -45.29684 25.84514  1.000 42.29973 ? 229 LEU E CG  1 
ATOM   6247 C CD1 . LEU E 5  215 ? -32.38175 -46.59916 25.08573  1.000 41.26304 ? 229 LEU E CD1 1 
ATOM   6248 C CD2 . LEU E 5  215 ? -30.73382 -45.10114 26.22217  1.000 39.64816 ? 229 LEU E CD2 1 
ATOM   6249 N N   . SER E 5  216 ? -32.56200 -41.23387 23.77489  1.000 57.74912 ? 230 SER E N   1 
ATOM   6250 C CA  . SER E 5  216 ? -33.06206 -40.30168 22.78005  1.000 61.21545 ? 230 SER E CA  1 
ATOM   6251 C C   . SER E 5  216 ? -33.58391 -41.06676 21.56650  1.000 61.05696 ? 230 SER E C   1 
ATOM   6252 O O   . SER E 5  216 ? -33.60409 -42.29969 21.53486  1.000 64.63306 ? 230 SER E O   1 
ATOM   6253 C CB  . SER E 5  216 ? -31.96489 -39.31976 22.37242  1.000 67.69408 ? 230 SER E CB  1 
ATOM   6254 O OG  . SER E 5  216 ? -30.69650 -39.95265 22.35920  1.000 72.95148 ? 230 SER E OG  1 
ATOM   6255 N N   . GLU E 5  217 ? -34.02009 -40.32280 20.54851  1.000 70.30578 ? 231 GLU E N   1 
ATOM   6256 C CA  . GLU E 5  217 ? -34.35934 -40.95738 19.28069  1.000 71.93632 ? 231 GLU E CA  1 
ATOM   6257 C C   . GLU E 5  217 ? -33.10562 -41.35260 18.51294  1.000 63.64620 ? 231 GLU E C   1 
ATOM   6258 O O   . GLU E 5  217 ? -33.13850 -42.29578 17.71459  1.000 72.62479 ? 231 GLU E O   1 
ATOM   6259 C CB  . GLU E 5  217 ? -35.23301 -40.02662 18.43914  1.000 63.49900 ? 231 GLU E CB  1 
ATOM   6260 N N   . ASN E 5  218 ? -31.99668 -40.65150 18.74544  1.000 68.31057 ? 232 ASN E N   1 
ATOM   6261 C CA  . ASN E 5  218 ? -30.71806 -40.98555 18.13289  1.000 76.48510 ? 232 ASN E CA  1 
ATOM   6262 C C   . ASN E 5  218 ? -30.01590 -42.14546 18.82630  1.000 77.17945 ? 232 ASN E C   1 
ATOM   6263 O O   . ASN E 5  218 ? -28.94423 -42.56022 18.37115  1.000 76.34776 ? 232 ASN E O   1 
ATOM   6264 C CB  . ASN E 5  218 ? -29.80252 -39.75795 18.12526  1.000 72.72134 ? 232 ASN E CB  1 
ATOM   6265 N N   . ASP E 5  219 ? -30.58142 -42.66823 19.91154  1.000 70.72392 ? 233 ASP E N   1 
ATOM   6266 C CA  . ASP E 5  219 ? -30.04327 -43.84554 20.57765  1.000 70.85371 ? 233 ASP E CA  1 
ATOM   6267 C C   . ASP E 5  219 ? -30.60920 -45.09582 19.91545  1.000 76.98756 ? 233 ASP E C   1 
ATOM   6268 O O   . ASP E 5  219 ? -31.82973 -45.24143 19.79175  1.000 72.44036 ? 233 ASP E O   1 
ATOM   6269 C CB  . ASP E 5  219 ? -30.38231 -43.82917 22.06973  1.000 62.75765 ? 233 ASP E CB  1 
ATOM   6270 C CG  . ASP E 5  219 ? -29.40243 -43.00143 22.88434  1.000 74.34549 ? 233 ASP E CG  1 
ATOM   6271 O OD1 . ASP E 5  219 ? -28.29152 -43.49827 23.16981  1.000 67.08810 ? 233 ASP E OD1 1 
ATOM   6272 O OD2 . ASP E 5  219 ? -29.74551 -41.85515 23.24463  1.000 76.06815 ? 233 ASP E OD2 1 
ATOM   6273 N N   . GLU E 5  220 ? -29.72170 -45.98896 19.48493  1.000 74.41325 ? 234 GLU E N   1 
ATOM   6274 C CA  . GLU E 5  220 ? -30.15069 -47.19179 18.78408  1.000 75.13228 ? 234 GLU E CA  1 
ATOM   6275 C C   . GLU E 5  220 ? -30.77367 -48.18876 19.75396  1.000 63.42159 ? 234 GLU E C   1 
ATOM   6276 O O   . GLU E 5  220 ? -30.28710 -48.38139 20.87173  1.000 67.06456 ? 234 GLU E O   1 
ATOM   6277 C CB  . GLU E 5  220 ? -28.96853 -47.83279 18.05756  1.000 75.16082 ? 234 GLU E CB  1 
ATOM   6278 N N   . TRP E 5  221 ? -31.85577 -48.83122 19.31562  1.000 55.72136 ? 235 TRP E N   1 
ATOM   6279 C CA  . TRP E 5  221 ? -32.58631 -49.78693 20.14548  1.000 60.47077 ? 235 TRP E CA  1 
ATOM   6280 C C   . TRP E 5  221 ? -32.97125 -50.98499 19.29001  1.000 58.77901 ? 235 TRP E C   1 
ATOM   6281 O O   . TRP E 5  221 ? -33.78277 -50.85677 18.36807  1.000 61.59420 ? 235 TRP E O   1 
ATOM   6282 C CB  . TRP E 5  221 ? -33.82632 -49.14574 20.76480  1.000 52.04363 ? 235 TRP E CB  1 
ATOM   6283 C CG  . TRP E 5  221 ? -34.47109 -49.98770 21.82241  1.000 54.66030 ? 235 TRP E CG  1 
ATOM   6284 C CD1 . TRP E 5  221 ? -35.67546 -50.62445 21.74303  1.000 50.48902 ? 235 TRP E CD1 1 
ATOM   6285 C CD2 . TRP E 5  221 ? -33.94507 -50.28479 23.12165  1.000 50.39574 ? 235 TRP E CD2 1 
ATOM   6286 N NE1 . TRP E 5  221 ? -35.93199 -51.29948 22.91208  1.000 49.16317 ? 235 TRP E NE1 1 
ATOM   6287 C CE2 . TRP E 5  221 ? -34.88492 -51.10656 23.77475  1.000 47.37781 ? 235 TRP E CE2 1 
ATOM   6288 C CE3 . TRP E 5  221 ? -32.77093 -49.93557 23.79561  1.000 48.91086 ? 235 TRP E CE3 1 
ATOM   6289 C CZ2 . TRP E 5  221 ? -34.68734 -51.58360 25.06873  1.000 44.10858 ? 235 TRP E CZ2 1 
ATOM   6290 C CZ3 . TRP E 5  221 ? -32.57629 -50.41082 25.07932  1.000 45.75505 ? 235 TRP E CZ3 1 
ATOM   6291 C CH2 . TRP E 5  221 ? -33.52860 -51.22700 25.70186  1.000 49.50282 ? 235 TRP E CH2 1 
ATOM   6292 N N   . THR E 5  222 ? -32.40229 -52.14763 19.60387  1.000 62.96631 ? 236 THR E N   1 
ATOM   6293 C CA  . THR E 5  222 ? -32.68266 -53.37827 18.87857  1.000 65.09226 ? 236 THR E CA  1 
ATOM   6294 C C   . THR E 5  222 ? -33.47090 -54.38808 19.70070  1.000 68.34191 ? 236 THR E C   1 
ATOM   6295 O O   . THR E 5  222 ? -33.76256 -55.47958 19.20051  1.000 74.79781 ? 236 THR E O   1 
ATOM   6296 C CB  . THR E 5  222 ? -31.37507 -54.02242 18.40050  1.000 67.02733 ? 236 THR E CB  1 
ATOM   6297 O OG1 . THR E 5  222 ? -30.75389 -54.71274 19.49219  1.000 70.03601 ? 236 THR E OG1 1 
ATOM   6298 C CG2 . THR E 5  222 ? -30.42038 -52.96322 17.87081  1.000 61.04544 ? 236 THR E CG2 1 
ATOM   6299 N N   . GLN E 5  223 ? -33.82665 -54.05763 20.93931  1.000 66.97414 ? 237 GLN E N   1 
ATOM   6300 C CA  . GLN E 5  223 ? -34.51050 -54.99645 21.81409  1.000 65.55754 ? 237 GLN E CA  1 
ATOM   6301 C C   . GLN E 5  223 ? -35.98109 -55.12916 21.42438  1.000 60.06041 ? 237 GLN E C   1 
ATOM   6302 O O   . GLN E 5  223 ? -36.47601 -54.47515 20.50216  1.000 67.84823 ? 237 GLN E O   1 
ATOM   6303 C CB  . GLN E 5  223 ? -34.37555 -54.56014 23.26959  1.000 59.72052 ? 237 GLN E CB  1 
ATOM   6304 C CG  . GLN E 5  223 ? -32.94741 -54.34545 23.71674  1.000 61.69080 ? 237 GLN E CG  1 
ATOM   6305 C CD  . GLN E 5  223 ? -32.37529 -55.56034 24.41413  1.000 74.09606 ? 237 GLN E CD  1 
ATOM   6306 O OE1 . GLN E 5  223 ? -32.63134 -55.78968 25.59652  1.000 72.26456 ? 237 GLN E OE1 1 
ATOM   6307 N NE2 . GLN E 5  223 ? -31.58962 -56.34496 23.68553  1.000 72.86920 ? 237 GLN E NE2 1 
ATOM   6308 N N   . ASP E 5  224 ? -36.69106 -55.99273 22.14968  1.000 59.70853 ? 238 ASP E N   1 
ATOM   6309 C CA  . ASP E 5  224 ? -38.10431 -56.24065 21.89671  1.000 61.21821 ? 238 ASP E CA  1 
ATOM   6310 C C   . ASP E 5  224 ? -39.00819 -55.35601 22.74489  1.000 60.78723 ? 238 ASP E C   1 
ATOM   6311 O O   . ASP E 5  224 ? -40.04533 -54.89004 22.26051  1.000 65.15705 ? 238 ASP E O   1 
ATOM   6312 C CB  . ASP E 5  224 ? -38.43208 -57.71384 22.15011  1.000 71.63982 ? 238 ASP E CB  1 
ATOM   6313 C CG  . ASP E 5  224 ? -37.79834 -58.63404 21.12706  1.000 83.19151 ? 238 ASP E CG  1 
ATOM   6314 O OD1 . ASP E 5  224 ? -37.59009 -58.19238 19.97700  1.000 82.84327 ? 238 ASP E OD1 1 
ATOM   6315 O OD2 . ASP E 5  224 ? -37.50685 -59.79804 21.47301  1.000 93.73990 ? 238 ASP E OD2 1 
ATOM   6316 N N   . ARG E 5  225 ? -38.64118 -55.11846 24.00188  1.000 54.77137 ? 239 ARG E N   1 
ATOM   6317 C CA  . ARG E 5  225 ? -39.42643 -54.23321 24.84556  1.000 47.78092 ? 239 ARG E CA  1 
ATOM   6318 C C   . ARG E 5  225 ? -39.35336 -52.80179 24.32192  1.000 42.96716 ? 239 ARG E C   1 
ATOM   6319 O O   . ARG E 5  225 ? -38.49279 -52.45091 23.50939  1.000 46.46791 ? 239 ARG E O   1 
ATOM   6320 C CB  . ARG E 5  225 ? -38.94314 -54.29491 26.29597  1.000 41.93820 ? 239 ARG E CB  1 
ATOM   6321 C CG  . ARG E 5  225 ? -37.49966 -53.85868 26.50809  1.000 45.50598 ? 239 ARG E CG  1 
ATOM   6322 C CD  . ARG E 5  225 ? -37.05846 -54.12753 27.94075  1.000 42.49352 ? 239 ARG E CD  1 
ATOM   6323 N NE  . ARG E 5  225 ? -35.62943 -53.91166 28.13849  1.000 47.17718 ? 239 ARG E NE  1 
ATOM   6324 C CZ  . ARG E 5  225 ? -35.08982 -52.76738 28.53731  1.000 43.74565 ? 239 ARG E CZ  1 
ATOM   6325 N NH1 . ARG E 5  225 ? -35.83295 -51.70032 28.78276  1.000 33.79247 ? 239 ARG E NH1 1 
ATOM   6326 N NH2 . ARG E 5  225 ? -33.77157 -52.69337 28.69939  1.000 37.37456 ? 239 ARG E NH2 1 
ATOM   6327 N N   . ALA E 5  226 ? -40.28303 -51.97413 24.79391  1.000 42.79160 ? 240 ALA E N   1 
ATOM   6328 C CA  . ALA E 5  226 ? -40.34690 -50.58889 24.35057  1.000 44.98176 ? 240 ALA E CA  1 
ATOM   6329 C C   . ALA E 5  226 ? -39.03657 -49.86909 24.64733  1.000 45.33318 ? 240 ALA E C   1 
ATOM   6330 O O   . ALA E 5  226 ? -38.36443 -50.13999 25.64659  1.000 36.38738 ? 240 ALA E O   1 
ATOM   6331 C CB  . ALA E 5  226 ? -41.51038 -49.86507 25.02996  1.000 41.11446 ? 240 ALA E CB  1 
ATOM   6332 N N   . LYS E 5  227 ? -38.66819 -48.95682 23.75601  1.000 43.26053 ? 241 LYS E N   1 
ATOM   6333 C CA  . LYS E 5  227 ? -37.45978 -48.16882 23.94223  1.000 40.79593 ? 241 LYS E CA  1 
ATOM   6334 C C   . LYS E 5  227 ? -37.58320 -47.33898 25.21432  1.000 33.01494 ? 241 LYS E C   1 
ATOM   6335 O O   . LYS E 5  227 ? -38.53892 -46.55861 25.34527  1.000 34.09849 ? 241 LYS E O   1 
ATOM   6336 C CB  . LYS E 5  227 ? -37.21010 -47.25985 22.74055  1.000 39.59523 ? 241 LYS E CB  1 
ATOM   6337 C CG  . LYS E 5  227 ? -35.75218 -46.84752 22.57594  1.000 40.04651 ? 241 LYS E CG  1 
ATOM   6338 C CD  . LYS E 5  227 ? -35.57332 -45.63385 21.66483  1.000 47.60852 ? 241 LYS E CD  1 
ATOM   6339 C CE  . LYS E 5  227 ? -36.67794 -45.51707 20.62369  1.000 57.97820 ? 241 LYS E CE  1 
ATOM   6340 N NZ  . LYS E 5  227 ? -36.55634 -46.54770 19.55519  1.000 63.82404 ? 241 LYS E NZ  1 
ATOM   6341 N N   . PRO E 5  228 ? -36.66581 -47.47741 26.16895  1.000 35.18842 ? 242 PRO E N   1 
ATOM   6342 C CA  . PRO E 5  228 ? -36.76068 -46.68662 27.40315  1.000 31.72300 ? 242 PRO E CA  1 
ATOM   6343 C C   . PRO E 5  228 ? -36.41012 -45.22711 27.16678  1.000 31.63234 ? 242 PRO E C   1 
ATOM   6344 O O   . PRO E 5  228 ? -35.33941 -44.75946 27.56790  1.000 31.96333 ? 242 PRO E O   1 
ATOM   6345 C CB  . PRO E 5  228 ? -35.75397 -47.36962 28.33519  1.000 31.27968 ? 242 PRO E CB  1 
ATOM   6346 C CG  . PRO E 5  228 ? -34.75415 -47.98909 27.41305  1.000 34.15800 ? 242 PRO E CG  1 
ATOM   6347 C CD  . PRO E 5  228 ? -35.49336 -48.36814 26.15867  1.000 33.52150 ? 242 PRO E CD  1 
ATOM   6348 N N   . VAL E 5  229 ? -37.31278 -44.50189 26.51014  1.000 28.55635 ? 243 VAL E N   1 
ATOM   6349 C CA  . VAL E 5  229 ? -37.08954 -43.10401 26.16248  1.000 28.89336 ? 243 VAL E CA  1 
ATOM   6350 C C   . VAL E 5  229 ? -37.42114 -42.21254 27.34958  1.000 33.00604 ? 243 VAL E C   1 
ATOM   6351 O O   . VAL E 5  229 ? -38.05369 -42.65344 28.31690  1.000 25.73152 ? 243 VAL E O   1 
ATOM   6352 C CB  . VAL E 5  229 ? -37.92828 -42.69696 24.93820  1.000 28.25264 ? 243 VAL E CB  1 
ATOM   6353 C CG1 . VAL E 5  229 ? -37.42127 -43.39341 23.69185  1.000 33.66914 ? 243 VAL E CG1 1 
ATOM   6354 C CG2 . VAL E 5  229 ? -39.39755 -43.01650 25.17633  1.000 23.17916 ? 243 VAL E CG2 1 
ATOM   6355 N N   . THR E 5  230 ? -36.99074 -40.95483 27.27945  1.000 28.93404 ? 244 THR E N   1 
ATOM   6356 C CA  . THR E 5  230 ? -37.44537 -39.94318 28.22290  1.000 25.69798 ? 244 THR E CA  1 
ATOM   6357 C C   . THR E 5  230 ? -38.96745 -39.88163 28.20567  1.000 29.28430 ? 244 THR E C   1 
ATOM   6358 O O   . THR E 5  230 ? -39.57707 -39.71951 27.14408  1.000 28.43566 ? 244 THR E O   1 
ATOM   6359 C CB  . THR E 5  230 ? -36.84224 -38.58563 27.85753  1.000 28.41665 ? 244 THR E CB  1 
ATOM   6360 O OG1 . THR E 5  230 ? -35.42127 -38.62549 28.04700  1.000 30.30419 ? 244 THR E OG1 1 
ATOM   6361 C CG2 . THR E 5  230 ? -37.43838 -37.47415 28.70930  1.000 21.67061 ? 244 THR E CG2 1 
ATOM   6362 N N   . GLN E 5  231 ? -39.58258 -40.03154 29.37559  1.000 28.55963 ? 245 GLN E N   1 
ATOM   6363 C CA  . GLN E 5  231 ? -41.03436 -40.11295 29.45659  1.000 26.12470 ? 245 GLN E CA  1 
ATOM   6364 C C   . GLN E 5  231 ? -41.48077 -39.73903 30.86128  1.000 33.66321 ? 245 GLN E C   1 
ATOM   6365 O O   . GLN E 5  231 ? -40.67911 -39.66178 31.79611  1.000 27.46159 ? 245 GLN E O   1 
ATOM   6366 C CB  . GLN E 5  231 ? -41.53313 -41.51509 29.09739  1.000 27.16495 ? 245 GLN E CB  1 
ATOM   6367 C CG  . GLN E 5  231 ? -41.01501 -42.59194 30.03581  1.000 27.16647 ? 245 GLN E CG  1 
ATOM   6368 C CD  . GLN E 5  231 ? -41.34672 -43.99240 29.56715  1.000 30.46214 ? 245 GLN E CD  1 
ATOM   6369 O OE1 . GLN E 5  231 ? -42.40478 -44.53238 29.88820  1.000 32.98426 ? 245 GLN E OE1 1 
ATOM   6370 N NE2 . GLN E 5  231 ? -40.43978 -44.59068 28.80289  1.000 29.56821 ? 245 GLN E NE2 1 
ATOM   6371 N N   . ILE E 5  232 ? -42.78475 -39.51809 30.99392  1.000 30.51735 ? 246 ILE E N   1 
ATOM   6372 C CA  . ILE E 5  232 ? -43.43248 -39.28337 32.27668  1.000 28.50156 ? 246 ILE E CA  1 
ATOM   6373 C C   . ILE E 5  232 ? -44.29324 -40.49668 32.59469  1.000 28.52228 ? 246 ILE E C   1 
ATOM   6374 O O   . ILE E 5  232 ? -45.10199 -40.92542 31.76333  1.000 30.70690 ? 246 ILE E O   1 
ATOM   6375 C CB  . ILE E 5  232 ? -44.27533 -37.99673 32.25584  1.000 29.89503 ? 246 ILE E CB  1 
ATOM   6376 C CG1 . ILE E 5  232 ? -43.36792 -36.76649 32.29381  1.000 30.85957 ? 246 ILE E CG1 1 
ATOM   6377 C CG2 . ILE E 5  232 ? -45.25847 -37.98089 33.41641  1.000 32.32030 ? 246 ILE E CG2 1 
ATOM   6378 C CD1 . ILE E 5  232 ? -44.11490 -35.45418 32.24496  1.000 31.05614 ? 246 ILE E CD1 1 
ATOM   6379 N N   . VAL E 5  233 ? -44.10514 -41.06058 33.78479  1.000 28.96039 ? 247 VAL E N   1 
ATOM   6380 C CA  . VAL E 5  233 ? -44.91109 -42.17108 34.27613  1.000 26.33419 ? 247 VAL E CA  1 
ATOM   6381 C C   . VAL E 5  233 ? -45.63774 -41.70044 35.52615  1.000 28.08780 ? 247 VAL E C   1 
ATOM   6382 O O   . VAL E 5  233 ? -45.01140 -41.16447 36.44826  1.000 31.23961 ? 247 VAL E O   1 
ATOM   6383 C CB  . VAL E 5  233 ? -44.05461 -43.41522 34.57156  1.000 27.41584 ? 247 VAL E CB  1 
ATOM   6384 C CG1 . VAL E 5  233 ? -44.94655 -44.62595 34.81331  1.000 23.33774 ? 247 VAL E CG1 1 
ATOM   6385 C CG2 . VAL E 5  233 ? -43.08671 -43.67561 33.42561  1.000 30.98465 ? 247 VAL E CG2 1 
ATOM   6386 N N   . SER E 5  234 ? -46.95325 -41.89879 35.55624  1.000 26.80394 ? 248 SER E N   1 
ATOM   6387 C CA  . SER E 5  234 ? -47.79264 -41.35693 36.61241  1.000 25.98255 ? 248 SER E CA  1 
ATOM   6388 C C   . SER E 5  234 ? -48.67371 -42.44333 37.21094  1.000 26.50802 ? 248 SER E C   1 
ATOM   6389 O O   . SER E 5  234 ? -48.89458 -43.50119 36.61605  1.000 29.11037 ? 248 SER E O   1 
ATOM   6390 C CB  . SER E 5  234 ? -48.67629 -40.21190 36.09449  1.000 28.31046 ? 248 SER E CB  1 
ATOM   6391 O OG  . SER E 5  234 ? -48.06882 -38.95217 36.31687  1.000 40.07114 ? 248 SER E OG  1 
ATOM   6392 N N   . ALA E 5  235 ? -49.16984 -42.15629 38.41214  1.000 26.71993 ? 249 ALA E N   1 
ATOM   6393 C CA  . ALA E 5  235 ? -50.19742 -42.94990 39.06816  1.000 24.82692 ? 249 ALA E CA  1 
ATOM   6394 C C   . ALA E 5  235 ? -51.03881 -41.99492 39.90095  1.000 27.45822 ? 249 ALA E C   1 
ATOM   6395 O O   . ALA E 5  235 ? -50.51144 -41.03177 40.46363  1.000 30.45909 ? 249 ALA E O   1 
ATOM   6396 C CB  . ALA E 5  235 ? -49.59606 -44.05758 39.93905  1.000 28.90968 ? 249 ALA E CB  1 
ATOM   6397 N N   . GLU E 5  236 ? -52.34351 -42.24909 39.96825  1.000 29.62525 ? 250 GLU E N   1 
ATOM   6398 C CA  . GLU E 5  236 ? -53.25961 -41.27216 40.53678  1.000 32.50153 ? 250 GLU E CA  1 
ATOM   6399 C C   . GLU E 5  236 ? -54.25199 -41.94431 41.47505  1.000 26.44896 ? 250 GLU E C   1 
ATOM   6400 O O   . GLU E 5  236 ? -54.32555 -43.17218 41.57734  1.000 25.72205 ? 250 GLU E O   1 
ATOM   6401 C CB  . GLU E 5  236 ? -54.00356 -40.50184 39.43775  1.000 33.36910 ? 250 GLU E CB  1 
ATOM   6402 C CG  . GLU E 5  236 ? -54.69128 -41.37800 38.40897  1.000 45.24708 ? 250 GLU E CG  1 
ATOM   6403 C CD  . GLU E 5  236 ? -55.37370 -40.56529 37.32432  1.000 50.66586 ? 250 GLU E CD  1 
ATOM   6404 O OE1 . GLU E 5  236 ? -54.66981 -39.82672 36.60257  1.000 45.91458 ? 250 GLU E OE1 1 
ATOM   6405 O OE2 . GLU E 5  236 ? -56.61257 -40.66133 37.19658  1.000 48.13414 ? 250 GLU E OE2 1 
ATOM   6406 N N   . ALA E 5  237 ? -55.01864 -41.10604 42.16832  1.000 27.82727 ? 251 ALA E N   1 
ATOM   6407 C CA  . ALA E 5  237 ? -56.04725 -41.55872 43.09140  1.000 29.23528 ? 251 ALA E CA  1 
ATOM   6408 C C   . ALA E 5  237 ? -57.07499 -40.44917 43.25093  1.000 30.99182 ? 251 ALA E C   1 
ATOM   6409 O O   . ALA E 5  237 ? -56.75830 -39.26607 43.09796  1.000 28.73295 ? 251 ALA E O   1 
ATOM   6410 C CB  . ALA E 5  237 ? -55.45692 -41.94377 44.45325  1.000 28.66490 ? 251 ALA E CB  1 
ATOM   6411 N N   . TRP E 5  238 ? -58.30845 -40.84736 43.54838  1.000 27.20785 ? 252 TRP E N   1 
ATOM   6412 C CA  . TRP E 5  238 ? -59.40424 -39.92492 43.79826  1.000 26.81229 ? 252 TRP E CA  1 
ATOM   6413 C C   . TRP E 5  238 ? -59.80974 -40.00380 45.26350  1.000 30.09175 ? 252 TRP E C   1 
ATOM   6414 O O   . TRP E 5  238 ? -59.60341 -41.02497 45.92628  1.000 28.01222 ? 252 TRP E O   1 
ATOM   6415 C CB  . TRP E 5  238 ? -60.61802 -40.24188 42.91393  1.000 27.04080 ? 252 TRP E CB  1 
ATOM   6416 C CG  . TRP E 5  238 ? -60.53193 -39.71553 41.50777  1.000 26.05332 ? 252 TRP E CG  1 
ATOM   6417 C CD1 . TRP E 5  238 ? -60.08526 -40.38889 40.40646  1.000 27.90890 ? 252 TRP E CD1 1 
ATOM   6418 C CD2 . TRP E 5  238 ? -60.92405 -38.41399 41.04947  1.000 24.13237 ? 252 TRP E CD2 1 
ATOM   6419 N NE1 . TRP E 5  238 ? -60.16713 -39.58536 39.29366  1.000 28.39638 ? 252 TRP E NE1 1 
ATOM   6420 C CE2 . TRP E 5  238 ? -60.67942 -38.36850 39.66122  1.000 30.15031 ? 252 TRP E CE2 1 
ATOM   6421 C CE3 . TRP E 5  238 ? -61.45528 -37.28292 41.67819  1.000 32.03068 ? 252 TRP E CE3 1 
ATOM   6422 C CZ2 . TRP E 5  238 ? -60.94422 -37.23525 38.89224  1.000 26.63571 ? 252 TRP E CZ2 1 
ATOM   6423 C CZ3 . TRP E 5  238 ? -61.71871 -36.15903 40.91260  1.000 27.91880 ? 252 TRP E CZ3 1 
ATOM   6424 C CH2 . TRP E 5  238 ? -61.46342 -36.14435 39.53468  1.000 31.04808 ? 252 TRP E CH2 1 
ATOM   6425 N N   . GLY E 5  239 ? -60.38857 -38.91494 45.76321  1.000 32.44765 ? 253 GLY E N   1 
ATOM   6426 C CA  . GLY E 5  239 ? -60.89814 -38.88934 47.12009  1.000 35.37804 ? 253 GLY E CA  1 
ATOM   6427 C C   . GLY E 5  239 ? -61.84395 -40.03878 47.40220  1.000 35.79959 ? 253 GLY E C   1 
ATOM   6428 O O   . GLY E 5  239 ? -62.60779 -40.44817 46.52313  1.000 30.28563 ? 253 GLY E O   1 
ATOM   6429 N N   . ARG E 5  240 ? -61.79246 -40.57844 48.61755  1.000 31.83590 ? 254 ARG E N   1 
ATOM   6430 C CA  . ARG E 5  240 ? -62.57389 -41.74933 49.00094  1.000 31.29320 ? 254 ARG E CA  1 
ATOM   6431 C C   . ARG E 5  240 ? -63.66855 -41.31126 49.96489  1.000 34.15573 ? 254 ARG E C   1 
ATOM   6432 O O   . ARG E 5  240 ? -63.38450 -40.94384 51.10997  1.000 40.29049 ? 254 ARG E O   1 
ATOM   6433 C CB  . ARG E 5  240 ? -61.68247 -42.81621 49.63302  1.000 36.49860 ? 254 ARG E CB  1 
ATOM   6434 C CG  . ARG E 5  240 ? -62.13605 -44.24485 49.37324  1.000 39.90722 ? 254 ARG E CG  1 
ATOM   6435 C CD  . ARG E 5  240 ? -61.01899 -45.23789 49.66460  1.000 48.85087 ? 254 ARG E CD  1 
ATOM   6436 N NE  . ARG E 5  240 ? -60.64887 -45.24394 51.07558  1.000 51.04422 ? 254 ARG E NE  1 
ATOM   6437 C CZ  . ARG E 5  240 ? -59.42855 -45.49410 51.53176  1.000 47.94372 ? 254 ARG E CZ  1 
ATOM   6438 N NH1 . ARG E 5  240 ? -58.42593 -45.76847 50.71295  1.000 40.19785 ? 254 ARG E NH1 1 
ATOM   6439 N NH2 . ARG E 5  240 ? -59.20810 -45.46706 52.84284  1.000 45.50580 ? 254 ARG E NH2 1 
ATOM   6440 N N   . ALA E 5  241 ? -64.91262 -41.35182 49.50124  1.000 35.65310 ? 255 ALA E N   1 
ATOM   6441 C CA  . ALA E 5  241 ? -66.06150 -41.03986 50.33484  1.000 41.27739 ? 255 ALA E CA  1 
ATOM   6442 C C   . ALA E 5  241 ? -66.60283 -42.30705 50.98979  1.000 49.08300 ? 255 ALA E C   1 
ATOM   6443 O O   . ALA E 5  241 ? -66.30427 -43.42894 50.57094  1.000 44.89863 ? 255 ALA E O   1 
ATOM   6444 C CB  . ALA E 5  241 ? -67.15690 -40.36012 49.51363  1.000 34.48709 ? 255 ALA E CB  1 
ATOM   6445 N N   . ASP E 5  242 ? -67.41143 -42.10690 52.02914  1.000 52.60394 ? 256 ASP E N   1 
ATOM   6446 C CA  . ASP E 5  242 ? -67.97869 -43.19508 52.82739  1.000 51.47815 ? 256 ASP E CA  1 
ATOM   6447 C C   . ASP E 5  242 ? -66.88594 -44.08621 53.41107  1.000 59.33554 ? 256 ASP E C   1 
ATOM   6448 O O   . ASP E 5  242 ? -66.55741 -43.98755 54.59391  1.000 56.89101 ? 256 ASP E O   1 
ATOM   6449 C CB  . ASP E 5  242 ? -68.95301 -44.03648 51.99630  1.000 48.47773 ? 256 ASP E CB  1 
ATOM   6450 C CG  . ASP E 5  242 ? -69.94420 -43.18955 51.22577  1.000 42.90815 ? 256 ASP E CG  1 
ATOM   6451 O OD1 . ASP E 5  242 ? -69.87963 -41.94784 51.33570  1.000 55.13431 ? 256 ASP E OD1 1 
ATOM   6452 O OD2 . ASP E 5  242 ? -70.79244 -43.76607 50.51462  1.000 46.03642 ? 256 ASP E OD2 1 
HETATM 6453 C C1  . NAG F 6  .   ? 32.72806  -3.18437  40.82130  1.000 44.67149 ? 1   NAG F C1  1 
HETATM 6454 C C2  . NAG F 6  .   ? 32.77198  -4.23787  41.93876  1.000 39.58858 ? 1   NAG F C2  1 
HETATM 6455 C C3  . NAG F 6  .   ? 33.08151  -3.58851  43.28862  1.000 44.98616 ? 1   NAG F C3  1 
HETATM 6456 C C4  . NAG F 6  .   ? 34.33329  -2.72753  43.19759  1.000 50.25768 ? 1   NAG F C4  1 
HETATM 6457 C C5  . NAG F 6  .   ? 34.15484  -1.70226  42.08512  1.000 55.14977 ? 1   NAG F C5  1 
HETATM 6458 C C6  . NAG F 6  .   ? 35.36394  -0.81962  41.87474  1.000 51.19416 ? 1   NAG F C6  1 
HETATM 6459 C C7  . NAG F 6  .   ? 31.42982  -6.29478  41.86321  1.000 35.65986 ? 1   NAG F C7  1 
HETATM 6460 C C8  . NAG F 6  .   ? 30.05108  -6.87594  41.95399  1.000 34.76165 ? 1   NAG F C8  1 
HETATM 6461 N N2  . NAG F 6  .   ? 31.51595  -4.96801  42.00254  1.000 34.42398 ? 1   NAG F N2  1 
HETATM 6462 O O3  . NAG F 6  .   ? 33.26445  -4.60459  44.26787  1.000 46.69355 ? 1   NAG F O3  1 
HETATM 6463 O O4  . NAG F 6  .   ? 34.56855  -2.07268  44.43940  1.000 60.30605 ? 1   NAG F O4  1 
HETATM 6464 O O5  . NAG F 6  .   ? 33.92743  -2.39219  40.84954  1.000 42.94580 ? 1   NAG F O5  1 
HETATM 6465 O O6  . NAG F 6  .   ? 36.48511  -1.56926  41.42695  1.000 44.11309 ? 1   NAG F O6  1 
HETATM 6466 O O7  . NAG F 6  .   ? 32.41964  -6.99448  41.67370  1.000 36.67992 ? 1   NAG F O7  1 
HETATM 6467 C C1  . NAG F 6  .   ? 35.89290  -2.40836  44.91806  1.000 56.72119 ? 2   NAG F C1  1 
HETATM 6468 C C2  . NAG F 6  .   ? 36.29448  -1.34874  45.94549  1.000 60.65825 ? 2   NAG F C2  1 
HETATM 6469 C C3  . NAG F 6  .   ? 37.67452  -1.66381  46.51694  1.000 61.35943 ? 2   NAG F C3  1 
HETATM 6470 C C4  . NAG F 6  .   ? 37.71833  -3.08729  47.05699  1.000 64.55028 ? 2   NAG F C4  1 
HETATM 6471 C C5  . NAG F 6  .   ? 37.25420  -4.07380  45.98879  1.000 61.49263 ? 2   NAG F C5  1 
HETATM 6472 C C6  . NAG F 6  .   ? 37.16169  -5.49456  46.49465  1.000 61.50711 ? 2   NAG F C6  1 
HETATM 6473 C C7  . NAG F 6  .   ? 35.24057  0.81501   45.46886  1.000 57.02121 ? 2   NAG F C7  1 
HETATM 6474 C C8  . NAG F 6  .   ? 35.38901  2.14393   44.79209  1.000 50.01708 ? 2   NAG F C8  1 
HETATM 6475 N N2  . NAG F 6  .   ? 36.27671  -0.02181  45.35164  1.000 53.60144 ? 2   NAG F N2  1 
HETATM 6476 O O3  . NAG F 6  .   ? 37.97970  -0.74022  47.55583  1.000 60.44965 ? 2   NAG F O3  1 
HETATM 6477 O O4  . NAG F 6  .   ? 39.04417  -3.41527  47.45716  1.000 67.97612 ? 2   NAG F O4  1 
HETATM 6478 O O5  . NAG F 6  .   ? 35.94455  -3.71164  45.52537  1.000 63.18257 ? 2   NAG F O5  1 
HETATM 6479 O O6  . NAG F 6  .   ? 37.31952  -6.43187  45.43838  1.000 76.17563 ? 2   NAG F O6  1 
HETATM 6480 O O7  . NAG F 6  .   ? 34.22941  0.51294   46.09482  1.000 71.13562 ? 2   NAG F O7  1 
HETATM 6481 C C1  . GOL G 7  .   ? 4.64598   11.79570  34.32635  1.000 50.00691 ? 201 GOL A C1  1 
HETATM 6482 O O1  . GOL G 7  .   ? 4.68935   13.10803  33.85746  1.000 48.04321 ? 201 GOL A O1  1 
HETATM 6483 C C2  . GOL G 7  .   ? 3.18636   11.51355  34.75661  1.000 47.99315 ? 201 GOL A C2  1 
HETATM 6484 O O2  . GOL G 7  .   ? 2.28431   11.78043  33.73791  1.000 64.25571 ? 201 GOL A O2  1 
HETATM 6485 C C3  . GOL G 7  .   ? 3.17473   10.02267  35.16717  1.000 40.21020 ? 201 GOL A C3  1 
HETATM 6486 O O3  . GOL G 7  .   ? 1.85584   9.70429   35.48525  1.000 46.90051 ? 201 GOL A O3  1 
HETATM 6487 C C1  . NAG H 8  .   ? -7.53932  -11.67421 17.96315  1.000 67.35914 ? 201 NAG B C1  1 
HETATM 6488 C C2  . NAG H 8  .   ? -8.38498  -12.57922 18.85717  1.000 72.43841 ? 201 NAG B C2  1 
HETATM 6489 C C3  . NAG H 8  .   ? -8.41370  -13.99780 18.29500  1.000 76.58784 ? 201 NAG B C3  1 
HETATM 6490 C C4  . NAG H 8  .   ? -8.87056  -13.98436 16.84207  1.000 85.52103 ? 201 NAG B C4  1 
HETATM 6491 C C5  . NAG H 8  .   ? -8.01213  -13.02147 16.02623  1.000 81.59501 ? 201 NAG B C5  1 
HETATM 6492 C C6  . NAG H 8  .   ? -8.49460  -12.86071 14.60325  1.000 79.92289 ? 201 NAG B C6  1 
HETATM 6493 C C7  . NAG H 8  .   ? -8.68101  -12.65064 21.29372  1.000 72.92639 ? 201 NAG B C7  1 
HETATM 6494 C C8  . NAG H 8  .   ? -7.99395  -12.63759 22.62622  1.000 70.16665 ? 201 NAG B C8  1 
HETATM 6495 N N2  . NAG H 8  .   ? -7.88398  -12.57916 20.22239  1.000 72.64800 ? 201 NAG B N2  1 
HETATM 6496 O O3  . NAG H 8  .   ? -9.29386  -14.80052 19.07348  1.000 69.72053 ? 201 NAG B O3  1 
HETATM 6497 O O4  . NAG H 8  .   ? -8.76881  -15.29014 16.28543  1.000 85.11013 ? 201 NAG B O4  1 
HETATM 6498 O O5  . NAG H 8  .   ? -8.04213  -11.71594 16.62162  1.000 76.21753 ? 201 NAG B O5  1 
HETATM 6499 O O6  . NAG H 8  .   ? -9.84646  -12.42473 14.55930  1.000 88.93037 ? 201 NAG B O6  1 
HETATM 6500 O O7  . NAG H 8  .   ? -9.90140  -12.72363 21.19200  1.000 78.24622 ? 201 NAG B O7  1 
HETATM 6501 C C   . ACT I 9  .   ? -1.89714  5.69963   37.88940  1.000 57.24936 ? 101 ACT C C   1 
HETATM 6502 O O   . ACT I 9  .   ? -1.64875  6.70535   37.16659  1.000 53.32445 ? 101 ACT C O   1 
HETATM 6503 O OXT . ACT I 9  .   ? -2.76113  4.79298   37.71796  1.000 54.64967 ? 101 ACT C OXT 1 
HETATM 6504 C CH3 . ACT I 9  .   ? -1.02764  5.54174   39.17363  1.000 44.27102 ? 101 ACT C CH3 1 
HETATM 6505 C C   . ACT J 9  .   ? -11.82317 -29.79706 62.76454  1.000 45.31790 ? 301 ACT D C   1 
HETATM 6506 O O   . ACT J 9  .   ? -11.88122 -29.17812 63.86575  1.000 42.77253 ? 301 ACT D O   1 
HETATM 6507 O OXT . ACT J 9  .   ? -10.83934 -29.93370 61.97821  1.000 40.03353 ? 301 ACT D OXT 1 
HETATM 6508 C CH3 . ACT J 9  .   ? -13.13840 -30.49389 62.29905  1.000 34.92486 ? 301 ACT D CH3 1 
HETATM 6509 C C   . ACT K 9  .   ? -23.45673 -34.33738 23.50052  0.000 30.88600 ? 301 ACT E C   1 
HETATM 6510 O O   . ACT K 9  .   ? -23.76433 -33.16756 23.14078  0.000 30.38373 ? 301 ACT E O   1 
HETATM 6511 O OXT . ACT K 9  .   ? -22.32547 -34.89866 23.48159  0.000 30.86594 ? 301 ACT E OXT 1 
HETATM 6512 C CH3 . ACT K 9  .   ? -24.62387 -35.22381 24.04541  0.000 31.60974 ? 301 ACT E CH3 1 
HETATM 6513 C C1  . GOL L 7  .   ? -7.68024  -21.14701 41.03985  1.000 41.02592 ? 302 GOL E C1  1 
HETATM 6514 O O1  . GOL L 7  .   ? -8.29659  -22.35746 40.74924  1.000 45.37463 ? 302 GOL E O1  1 
HETATM 6515 C C2  . GOL L 7  .   ? -8.34050  -20.07583 40.16233  1.000 47.60473 ? 302 GOL E C2  1 
HETATM 6516 O O2  . GOL L 7  .   ? -8.36487  -20.44533 38.82162  1.000 41.16499 ? 302 GOL E O2  1 
HETATM 6517 C C3  . GOL L 7  .   ? -9.75283  -19.91385 40.76336  1.000 32.47416 ? 302 GOL E C3  1 
HETATM 6518 O O3  . GOL L 7  .   ? -10.36009 -21.16260 40.68955  1.000 41.56807 ? 302 GOL E O3  1 
HETATM 6519 O O   . HOH M 10 .   ? 42.13418  -12.14833 25.04120  1.000 46.47349 ? 301 HOH A O   1 
HETATM 6520 O O   . HOH M 10 .   ? 42.26458  1.89885   32.13038  1.000 31.13762 ? 302 HOH A O   1 
HETATM 6521 O O   . HOH M 10 .   ? 30.10733  -6.59716  6.97723   1.000 31.54861 ? 303 HOH A O   1 
HETATM 6522 O O   . HOH M 10 .   ? 40.17349  -14.26976 26.97101  1.000 47.54489 ? 304 HOH A O   1 
HETATM 6523 O O   . HOH M 10 .   ? 16.74979  -15.01199 49.31262  1.000 37.86963 ? 305 HOH A O   1 
HETATM 6524 O O   . HOH M 10 .   ? 18.64981  0.64339   26.73336  1.000 34.71170 ? 306 HOH A O   1 
HETATM 6525 O O   . HOH M 10 .   ? 11.99976  9.93121   14.28222  1.000 55.27139 ? 307 HOH A O   1 
HETATM 6526 O O   . HOH M 10 .   ? 15.72498  -16.69116 62.74382  1.000 62.22471 ? 308 HOH A O   1 
HETATM 6527 O O   . HOH M 10 .   ? 16.00521  -4.44348  25.18163  1.000 36.47143 ? 309 HOH A O   1 
HETATM 6528 O O   . HOH M 10 .   ? 10.57419  -3.30791  21.51762  1.000 26.86383 ? 310 HOH A O   1 
HETATM 6529 O O   . HOH M 10 .   ? 14.51337  -1.42477  32.48059  1.000 29.79338 ? 311 HOH A O   1 
HETATM 6530 O O   . HOH M 10 .   ? 37.89965  7.17379   26.75339  1.000 36.62445 ? 312 HOH A O   1 
HETATM 6531 O O   . HOH M 10 .   ? 33.15274  6.96758   23.79562  1.000 38.48949 ? 313 HOH A O   1 
HETATM 6532 O O   . HOH M 10 .   ? 22.48021  -18.52078 29.08297  1.000 47.48999 ? 314 HOH A O   1 
HETATM 6533 O O   . HOH M 10 .   ? 27.80777  -0.55810  14.47510  1.000 24.33566 ? 315 HOH A O   1 
HETATM 6534 O O   . HOH M 10 .   ? 29.65623  -1.15070  30.08566  1.000 33.14914 ? 316 HOH A O   1 
HETATM 6535 O O   . HOH M 10 .   ? 27.05134  -8.58195  42.09645  1.000 28.98303 ? 317 HOH A O   1 
HETATM 6536 O O   . HOH M 10 .   ? 24.31745  -14.48580 27.74789  1.000 27.52379 ? 318 HOH A O   1 
HETATM 6537 O O   . HOH M 10 .   ? 17.07049  -16.07211 34.52905  1.000 34.36460 ? 319 HOH A O   1 
HETATM 6538 O O   . HOH M 10 .   ? 27.10316  -1.68628  34.64895  1.000 47.52664 ? 320 HOH A O   1 
HETATM 6539 O O   . HOH M 10 .   ? 28.26605  -18.13554 33.30511  1.000 33.11234 ? 321 HOH A O   1 
HETATM 6540 O O   . HOH M 10 .   ? 40.88648  7.09249   19.92392  1.000 42.55516 ? 322 HOH A O   1 
HETATM 6541 O O   . HOH M 10 .   ? 16.50222  -4.47979  21.15053  1.000 22.57986 ? 323 HOH A O   1 
HETATM 6542 O O   . HOH M 10 .   ? 14.05060  0.35323   36.22337  1.000 23.96587 ? 324 HOH A O   1 
HETATM 6543 O O   . HOH M 10 .   ? 12.42100  3.45170   55.14306  1.000 41.91197 ? 325 HOH A O   1 
HETATM 6544 O O   . HOH M 10 .   ? 35.40071  -1.01765  29.46122  1.000 28.64260 ? 326 HOH A O   1 
HETATM 6545 O O   . HOH M 10 .   ? 14.36374  9.45830   22.06750  1.000 36.50754 ? 327 HOH A O   1 
HETATM 6546 O O   . HOH M 10 .   ? 34.39840  -5.69617  34.59663  1.000 30.94320 ? 328 HOH A O   1 
HETATM 6547 O O   . HOH M 10 .   ? 23.59231  -13.02012 38.48263  1.000 24.97308 ? 329 HOH A O   1 
HETATM 6548 O O   . HOH M 10 .   ? 16.99739  5.02557   36.55348  1.000 25.65982 ? 330 HOH A O   1 
HETATM 6549 O O   . HOH M 10 .   ? 12.22421  -15.01281 32.84977  1.000 37.53925 ? 331 HOH A O   1 
HETATM 6550 O O   . HOH M 10 .   ? 4.24188   6.97330   43.84770  1.000 40.63063 ? 332 HOH A O   1 
HETATM 6551 O O   . HOH M 10 .   ? 7.10081   -4.24859  18.87171  1.000 22.63111 ? 333 HOH A O   1 
HETATM 6552 O O   . HOH M 10 .   ? 19.38419  6.75111   38.65195  1.000 44.83105 ? 334 HOH A O   1 
HETATM 6553 O O   . HOH M 10 .   ? 22.48740  -19.38834 39.20931  1.000 39.26049 ? 335 HOH A O   1 
HETATM 6554 O O   . HOH M 10 .   ? 25.96635  -2.44118  38.94688  1.000 29.87457 ? 336 HOH A O   1 
HETATM 6555 O O   . HOH M 10 .   ? 8.20398   -4.75312  27.79182  1.000 22.65451 ? 337 HOH A O   1 
HETATM 6556 O O   . HOH M 10 .   ? 6.49878   -12.59330 36.26835  1.000 23.74700 ? 338 HOH A O   1 
HETATM 6557 O O   . HOH M 10 .   ? 41.43669  -8.56216  25.03073  1.000 34.55880 ? 339 HOH A O   1 
HETATM 6558 O O   . HOH M 10 .   ? 39.12146  -6.51343  15.49632  1.000 31.29033 ? 340 HOH A O   1 
HETATM 6559 O O   . HOH M 10 .   ? 12.64889  -6.62458  29.46384  1.000 29.21836 ? 341 HOH A O   1 
HETATM 6560 O O   . HOH M 10 .   ? 8.79434   -6.08436  34.01296  1.000 21.40135 ? 342 HOH A O   1 
HETATM 6561 O O   . HOH M 10 .   ? 24.20563  -10.21488 47.51722  1.000 34.18770 ? 343 HOH A O   1 
HETATM 6562 O O   . HOH M 10 .   ? 28.84911  2.39599   22.30889  1.000 24.16835 ? 344 HOH A O   1 
HETATM 6563 O O   . HOH M 10 .   ? 10.97716  6.57019   51.83546  1.000 31.56361 ? 345 HOH A O   1 
HETATM 6564 O O   . HOH M 10 .   ? 23.48190  -1.28614  40.55736  1.000 34.97757 ? 346 HOH A O   1 
HETATM 6565 O O   . HOH M 10 .   ? 8.61583   -5.24932  30.29520  1.000 19.67097 ? 347 HOH A O   1 
HETATM 6566 O O   . HOH M 10 .   ? 22.49405  -10.82531 49.65551  1.000 28.80696 ? 348 HOH A O   1 
HETATM 6567 O O   . HOH M 10 .   ? -1.65520  -6.88720  18.45902  1.000 32.68462 ? 349 HOH A O   1 
HETATM 6568 O O   . HOH M 10 .   ? 11.32210  -12.49981 30.60102  1.000 32.58790 ? 350 HOH A O   1 
HETATM 6569 O O   . HOH M 10 .   ? 6.20988   5.00464   28.05699  1.000 34.03793 ? 351 HOH A O   1 
HETATM 6570 O O   . HOH M 10 .   ? 38.46086  -0.26431  17.22582  1.000 34.15157 ? 352 HOH A O   1 
HETATM 6571 O O   . HOH M 10 .   ? 14.51714  -4.77236  19.51961  1.000 28.03591 ? 353 HOH A O   1 
HETATM 6572 O O   . HOH M 10 .   ? 35.51474  -17.01669 26.03917  1.000 39.46619 ? 354 HOH A O   1 
HETATM 6573 O O   . HOH M 10 .   ? 4.57110   14.68767  26.44997  1.000 53.34959 ? 355 HOH A O   1 
HETATM 6574 O O   . HOH M 10 .   ? 36.74451  2.06455   20.79646  1.000 41.73269 ? 356 HOH A O   1 
HETATM 6575 O O   . HOH M 10 .   ? 16.54017  -1.85217  25.36456  1.000 28.10188 ? 357 HOH A O   1 
HETATM 6576 O O   . HOH M 10 .   ? 11.43632  14.88957  24.38564  1.000 52.01842 ? 358 HOH A O   1 
HETATM 6577 O O   . HOH M 10 .   ? 32.12146  -4.85551  10.19823  1.000 26.66698 ? 359 HOH A O   1 
HETATM 6578 O O   . HOH M 10 .   ? 4.17406   -17.30186 31.36304  1.000 49.28011 ? 360 HOH A O   1 
HETATM 6579 O O   . HOH M 10 .   ? 28.52927  -17.45125 30.80688  1.000 29.62429 ? 361 HOH A O   1 
HETATM 6580 O O   . HOH M 10 .   ? 40.96531  2.95651   28.40966  1.000 41.15607 ? 362 HOH A O   1 
HETATM 6581 O O   . HOH M 10 .   ? 35.36142  -15.33207 18.50221  1.000 38.16980 ? 363 HOH A O   1 
HETATM 6582 O O   . HOH M 10 .   ? 34.22773  -16.79786 36.49354  1.000 39.32223 ? 364 HOH A O   1 
HETATM 6583 O O   . HOH M 10 .   ? 18.12245  -15.19093 43.36742  1.000 39.22856 ? 365 HOH A O   1 
HETATM 6584 O O   . HOH M 10 .   ? 17.00807  -13.84260 45.69632  1.000 31.23090 ? 366 HOH A O   1 
HETATM 6585 O O   . HOH M 10 .   ? 36.97713  -8.49812  5.53612   1.000 38.91412 ? 367 HOH A O   1 
HETATM 6586 O O   . HOH M 10 .   ? 34.08299  -12.45715 12.17839  1.000 47.80206 ? 368 HOH A O   1 
HETATM 6587 O O   . HOH M 10 .   ? 44.25523  -7.74702  30.76665  1.000 43.22966 ? 369 HOH A O   1 
HETATM 6588 O O   . HOH M 10 .   ? 39.825    3.525     25.308    1.000 33.69477 ? 370 HOH A O   1 
HETATM 6589 O O   . HOH M 10 .   ? 28.41567  -1.79171  39.85406  1.000 41.88198 ? 371 HOH A O   1 
HETATM 6590 O O   . HOH M 10 .   ? 29.86337  -15.02304 18.89967  1.000 40.81127 ? 372 HOH A O   1 
HETATM 6591 O O   . HOH M 10 .   ? 17.30477  -12.72302 27.89391  1.000 33.61179 ? 373 HOH A O   1 
HETATM 6592 O O   . HOH M 10 .   ? 29.66325  0.56661   9.10530   1.000 44.01980 ? 374 HOH A O   1 
HETATM 6593 O O   . HOH M 10 .   ? 13.67980  8.82120   45.77193  1.000 46.30105 ? 375 HOH A O   1 
HETATM 6594 O O   . HOH M 10 .   ? 30.50257  -12.06131 10.19475  1.000 37.73840 ? 376 HOH A O   1 
HETATM 6595 O O   . HOH M 10 .   ? 26.87862  -2.35179  12.95706  1.000 37.25188 ? 377 HOH A O   1 
HETATM 6596 O O   . HOH M 10 .   ? 36.18730  -11.92488 8.28471   1.000 57.33086 ? 378 HOH A O   1 
HETATM 6597 O O   . HOH M 10 .   ? -3.29254  -12.21732 18.57279  1.000 55.76735 ? 379 HOH A O   1 
HETATM 6598 O O   . HOH M 10 .   ? 10.04501  2.10758   56.13518  1.000 42.73919 ? 380 HOH A O   1 
HETATM 6599 O O   . HOH M 10 .   ? 43.10734  -5.67660  9.65193   1.000 41.77303 ? 381 HOH A O   1 
HETATM 6600 O O   . HOH M 10 .   ? 10.20517  -6.36431  20.49710  1.000 28.41898 ? 382 HOH A O   1 
HETATM 6601 O O   . HOH M 10 .   ? 21.59714  -15.54420 27.62205  1.000 41.29150 ? 383 HOH A O   1 
HETATM 6602 O O   . HOH M 10 .   ? 29.33943  -1.65159  34.44222  1.000 37.51093 ? 384 HOH A O   1 
HETATM 6603 O O   . HOH M 10 .   ? 13.51918  15.69136  32.71228  1.000 40.96426 ? 385 HOH A O   1 
HETATM 6604 O O   . HOH M 10 .   ? 6.29738   -8.98717  23.42786  1.000 46.52314 ? 386 HOH A O   1 
HETATM 6605 O O   . HOH M 10 .   ? 17.59081  1.64811   52.57017  1.000 39.69208 ? 387 HOH A O   1 
HETATM 6606 O O   . HOH M 10 .   ? 32.51075  -10.34875 42.52821  1.000 43.53648 ? 388 HOH A O   1 
HETATM 6607 O O   . HOH M 10 .   ? 36.82570  -16.40942 32.53998  1.000 41.64587 ? 389 HOH A O   1 
HETATM 6608 O O   . HOH M 10 .   ? 13.40636  -8.03402  27.35300  1.000 35.13990 ? 390 HOH A O   1 
HETATM 6609 O O   . HOH M 10 .   ? 18.32747  2.81397   22.48824  1.000 38.27565 ? 391 HOH A O   1 
HETATM 6610 O O   . HOH M 10 .   ? 16.82778  12.80763  26.73667  1.000 38.58116 ? 392 HOH A O   1 
HETATM 6611 O O   . HOH M 10 .   ? 29.57572  -12.94003 16.64212  1.000 30.89709 ? 393 HOH A O   1 
HETATM 6612 O O   . HOH M 10 .   ? 36.85115  -2.01921  4.33137   1.000 49.94805 ? 394 HOH A O   1 
HETATM 6613 O O   . HOH M 10 .   ? 7.21927   -15.41377 30.64028  1.000 45.64506 ? 395 HOH A O   1 
HETATM 6614 O O   . HOH M 10 .   ? 25.64169  4.29534   28.45469  1.000 43.66031 ? 396 HOH A O   1 
HETATM 6615 O O   . HOH M 10 .   ? 4.64202   8.78149   42.20104  1.000 43.70379 ? 397 HOH A O   1 
HETATM 6616 O O   . HOH M 10 .   ? 30.14965  -15.98787 23.59051  1.000 32.40148 ? 398 HOH A O   1 
HETATM 6617 O O   . HOH M 10 .   ? 22.00921  3.73142   30.71517  1.000 42.78524 ? 399 HOH A O   1 
HETATM 6618 O O   . HOH M 10 .   ? 20.29059  0.05832   14.00999  1.000 44.57623 ? 400 HOH A O   1 
HETATM 6619 O O   . HOH M 10 .   ? 9.95620   -9.07454  31.61310  1.000 34.00083 ? 401 HOH A O   1 
HETATM 6620 O O   . HOH M 10 .   ? 25.88884  -1.09344  36.55250  1.000 43.01800 ? 402 HOH A O   1 
HETATM 6621 O O   . HOH M 10 .   ? 30.29061  6.26094   23.97145  1.000 48.67792 ? 403 HOH A O   1 
HETATM 6622 O O   . HOH M 10 .   ? 30.17650  1.72804   14.15067  1.000 46.39257 ? 404 HOH A O   1 
HETATM 6623 O O   . HOH M 10 .   ? 21.77855  3.44421   33.09848  1.000 48.09346 ? 405 HOH A O   1 
HETATM 6624 O O   . HOH M 10 .   ? 8.24209   -8.81444  24.60826  1.000 37.57839 ? 406 HOH A O   1 
HETATM 6625 O O   . HOH M 10 .   ? 25.00837  -4.44405  8.01955   1.000 39.99503 ? 407 HOH A O   1 
HETATM 6626 O O   . HOH M 10 .   ? 28.09347  1.44918   48.87776  1.000 52.16166 ? 408 HOH A O   1 
HETATM 6627 O O   . HOH M 10 .   ? 17.97792  6.16037   45.74098  1.000 50.24248 ? 409 HOH A O   1 
HETATM 6628 O O   . HOH M 10 .   ? 3.26445   -18.07116 33.27536  1.000 51.40721 ? 410 HOH A O   1 
HETATM 6629 O O   . HOH M 10 .   ? 5.40627   -4.78768  16.99734  1.000 32.21763 ? 411 HOH A O   1 
HETATM 6630 O O   . HOH M 10 .   ? 33.12059  3.68603   15.32508  1.000 42.61119 ? 412 HOH A O   1 
HETATM 6631 O O   . HOH M 10 .   ? 11.63676  5.52709   54.29449  1.000 41.63664 ? 413 HOH A O   1 
HETATM 6632 O O   . HOH M 10 .   ? 8.99811   -8.23203  29.61506  1.000 43.17118 ? 414 HOH A O   1 
HETATM 6633 O O   . HOH M 10 .   ? 17.78722  -11.51756 26.02259  1.000 38.40297 ? 415 HOH A O   1 
HETATM 6634 O O   . HOH M 10 .   ? 15.69499  8.13961   44.46720  1.000 42.26617 ? 416 HOH A O   1 
HETATM 6635 O O   . HOH M 10 .   ? 4.71236   6.86787   52.14255  1.000 52.72882 ? 417 HOH A O   1 
HETATM 6636 O O   . HOH M 10 .   ? 38.46212  -10.73516 5.24705   1.000 47.52945 ? 418 HOH A O   1 
HETATM 6637 O O   . HOH M 10 .   ? 4.40821   18.02492  30.65348  1.000 55.32692 ? 419 HOH A O   1 
HETATM 6638 O O   . HOH N 10 .   ? 34.562    -24.586   -7.445    1.000 84.73394 ? 301 HOH B O   1 
HETATM 6639 O O   . HOH N 10 .   ? -9.68126  -2.59872  35.89274  1.000 34.66349 ? 302 HOH B O   1 
HETATM 6640 O O   . HOH N 10 .   ? 5.77546   -13.60759 39.04351  1.000 26.96604 ? 303 HOH B O   1 
HETATM 6641 O O   . HOH N 10 .   ? 20.60729  -12.30151 56.51165  1.000 48.62508 ? 304 HOH B O   1 
HETATM 6642 O O   . HOH N 10 .   ? 19.12090  -3.72200  8.25860   1.000 35.06464 ? 305 HOH B O   1 
HETATM 6643 O O   . HOH N 10 .   ? -8.71056  -11.04879 53.16554  1.000 41.40290 ? 306 HOH B O   1 
HETATM 6644 O O   . HOH N 10 .   ? -8.63868  -6.90647  32.58199  1.000 29.13203 ? 307 HOH B O   1 
HETATM 6645 O O   . HOH N 10 .   ? -0.12658  -0.29144  43.37314  1.000 35.93322 ? 308 HOH B O   1 
HETATM 6646 O O   . HOH N 10 .   ? 6.22635   -15.61591 44.25896  1.000 28.91143 ? 309 HOH B O   1 
HETATM 6647 O O   . HOH N 10 .   ? -5.65082  4.59149   38.00922  1.000 38.77274 ? 310 HOH B O   1 
HETATM 6648 O O   . HOH N 10 .   ? -7.04617  -1.83600  36.29012  1.000 27.87440 ? 311 HOH B O   1 
HETATM 6649 O O   . HOH N 10 .   ? 23.30824  -5.49507  9.60719   1.000 29.57532 ? 312 HOH B O   1 
HETATM 6650 O O   . HOH N 10 .   ? 5.14650   -11.20367 32.07978  1.000 29.33433 ? 313 HOH B O   1 
HETATM 6651 O O   . HOH N 10 .   ? 12.51241  -24.12450 5.53129   1.000 54.01618 ? 314 HOH B O   1 
HETATM 6652 O O   . HOH N 10 .   ? 2.99326   -18.61995 45.44933  1.000 39.42923 ? 315 HOH B O   1 
HETATM 6653 O O   . HOH N 10 .   ? 21.65402  -7.10489  14.35467  1.000 26.04838 ? 316 HOH B O   1 
HETATM 6654 O O   . HOH N 10 .   ? -7.65001  -11.46613 57.93084  1.000 51.99969 ? 317 HOH B O   1 
HETATM 6655 O O   . HOH N 10 .   ? 7.89622   -14.82231 42.35235  1.000 34.95985 ? 318 HOH B O   1 
HETATM 6656 O O   . HOH N 10 .   ? -11.12631 -1.49865  30.69280  1.000 47.04649 ? 319 HOH B O   1 
HETATM 6657 O O   . HOH N 10 .   ? 3.54466   -18.38294 51.25770  1.000 30.88427 ? 320 HOH B O   1 
HETATM 6658 O O   . HOH N 10 .   ? 9.82395   -8.77791  21.94381  1.000 32.01913 ? 321 HOH B O   1 
HETATM 6659 O O   . HOH N 10 .   ? -10.10096 -4.86721  37.72908  1.000 28.25184 ? 322 HOH B O   1 
HETATM 6660 O O   . HOH N 10 .   ? 0.72182   -18.73880 48.45118  1.000 34.95445 ? 323 HOH B O   1 
HETATM 6661 O O   . HOH N 10 .   ? -4.80364  -9.87001  41.43485  1.000 21.60873 ? 324 HOH B O   1 
HETATM 6662 O O   . HOH N 10 .   ? 2.59960   -7.81227  53.57170  1.000 38.90078 ? 325 HOH B O   1 
HETATM 6663 O O   . HOH N 10 .   ? 3.10031   -12.32351 56.52154  1.000 27.98264 ? 326 HOH B O   1 
HETATM 6664 O O   . HOH N 10 .   ? 14.74970  -10.96743 24.32685  1.000 34.25618 ? 327 HOH B O   1 
HETATM 6665 O O   . HOH N 10 .   ? 22.92872  -10.23616 8.00298   1.000 21.19651 ? 328 HOH B O   1 
HETATM 6666 O O   . HOH N 10 .   ? 6.99831   -1.32345  15.24501  1.000 28.94344 ? 329 HOH B O   1 
HETATM 6667 O O   . HOH N 10 .   ? 25.91227  -11.94136 15.61449  1.000 42.77056 ? 330 HOH B O   1 
HETATM 6668 O O   . HOH N 10 .   ? 8.77928   -8.75958  34.49395  1.000 21.79469 ? 331 HOH B O   1 
HETATM 6669 O O   . HOH N 10 .   ? 14.44302  -0.34795  1.48277   1.000 67.65853 ? 332 HOH B O   1 
HETATM 6670 O O   . HOH N 10 .   ? 25.79154  -15.95281 7.39010   1.000 38.09479 ? 333 HOH B O   1 
HETATM 6671 O O   . HOH N 10 .   ? -11.63674 -12.66887 47.74822  1.000 28.07522 ? 334 HOH B O   1 
HETATM 6672 O O   . HOH N 10 .   ? 7.27188   -9.16202  3.72274   1.000 37.27629 ? 335 HOH B O   1 
HETATM 6673 O O   . HOH N 10 .   ? 13.13275  -8.04056  36.97724  1.000 19.59407 ? 336 HOH B O   1 
HETATM 6674 O O   . HOH N 10 .   ? 19.51360  -11.19016 23.40693  1.000 37.08305 ? 337 HOH B O   1 
HETATM 6675 O O   . HOH N 10 .   ? 14.90241  0.02715   7.03094   1.000 36.96018 ? 338 HOH B O   1 
HETATM 6676 O O   . HOH N 10 .   ? -9.17121  -7.08733  53.19102  1.000 40.72706 ? 339 HOH B O   1 
HETATM 6677 O O   . HOH N 10 .   ? 25.203    -15.262   -1.126    1.000 39.10781 ? 340 HOH B O   1 
HETATM 6678 O O   . HOH N 10 .   ? 14.12245  -13.85106 49.24194  1.000 35.84975 ? 341 HOH B O   1 
HETATM 6679 O O   . HOH N 10 .   ? 27.35638  -13.22674 1.85306   1.000 33.31526 ? 342 HOH B O   1 
HETATM 6680 O O   . HOH N 10 .   ? -4.10232  8.95633   32.00781  1.000 48.13218 ? 343 HOH B O   1 
HETATM 6681 O O   . HOH N 10 .   ? 24.85335  -13.46022 1.00073   1.000 27.31592 ? 344 HOH B O   1 
HETATM 6682 O O   . HOH N 10 .   ? 23.91104  -0.04284  18.93624  1.000 33.39152 ? 345 HOH B O   1 
HETATM 6683 O O   . HOH N 10 .   ? -3.90080  -8.98555  26.62700  1.000 32.68794 ? 346 HOH B O   1 
HETATM 6684 O O   . HOH N 10 .   ? 25.66605  -10.31477 13.59854  1.000 32.77829 ? 347 HOH B O   1 
HETATM 6685 O O   . HOH N 10 .   ? 12.23570  4.16381   15.02545  1.000 33.05790 ? 348 HOH B O   1 
HETATM 6686 O O   . HOH N 10 .   ? -8.52480  -9.48503  50.66269  1.000 39.94068 ? 349 HOH B O   1 
HETATM 6687 O O   . HOH N 10 .   ? -9.84010  -5.41470  27.70374  1.000 40.26423 ? 350 HOH B O   1 
HETATM 6688 O O   . HOH N 10 .   ? -3.43779  -13.36042 38.50604  1.000 23.12491 ? 351 HOH B O   1 
HETATM 6689 O O   . HOH N 10 .   ? 5.94898   5.51397   23.50659  1.000 34.84666 ? 352 HOH B O   1 
HETATM 6690 O O   . HOH N 10 .   ? 23.795    -16.194   -8.293    1.000 37.23684 ? 353 HOH B O   1 
HETATM 6691 O O   . HOH N 10 .   ? -2.96186  -10.60017 57.83049  1.000 47.76018 ? 354 HOH B O   1 
HETATM 6692 O O   . HOH N 10 .   ? 4.53251   5.51612   26.20312  1.000 39.73370 ? 355 HOH B O   1 
HETATM 6693 O O   . HOH N 10 .   ? 12.29848  -11.11435 25.10774  1.000 48.36978 ? 356 HOH B O   1 
HETATM 6694 O O   . HOH N 10 .   ? 10.59263  3.48598   11.24285  1.000 43.50545 ? 357 HOH B O   1 
HETATM 6695 O O   . HOH N 10 .   ? -10.80917 -17.05148 15.00495  1.000 65.98278 ? 358 HOH B O   1 
HETATM 6696 O O   . HOH N 10 .   ? -5.37255  -15.45905 44.75875  1.000 26.84642 ? 359 HOH B O   1 
HETATM 6697 O O   . HOH N 10 .   ? 19.54288  -20.98142 -12.26284 1.000 52.04788 ? 360 HOH B O   1 
HETATM 6698 O O   . HOH N 10 .   ? 19.18859  1.65491   16.69548  1.000 43.96791 ? 361 HOH B O   1 
HETATM 6699 O O   . HOH N 10 .   ? 6.50701   -15.69966 52.11544  1.000 37.50377 ? 362 HOH B O   1 
HETATM 6700 O O   . HOH N 10 .   ? -11.14195 -6.74996  33.65714  1.000 40.99676 ? 363 HOH B O   1 
HETATM 6701 O O   . HOH N 10 .   ? 8.76005   -6.31964  18.39400  1.000 25.48079 ? 364 HOH B O   1 
HETATM 6702 O O   . HOH N 10 .   ? -2.97527  -15.79583 34.12671  1.000 41.19647 ? 365 HOH B O   1 
HETATM 6703 O O   . HOH N 10 .   ? 11.77046  -18.49154 10.91433  1.000 43.71284 ? 366 HOH B O   1 
HETATM 6704 O O   . HOH N 10 .   ? 0.94193   -5.02773  43.38438  1.000 33.45352 ? 367 HOH B O   1 
HETATM 6705 O O   . HOH N 10 .   ? -3.08597  -15.86933 31.80227  1.000 43.74556 ? 368 HOH B O   1 
HETATM 6706 O O   . HOH N 10 .   ? 14.01250  -14.42464 46.33426  1.000 33.37471 ? 369 HOH B O   1 
HETATM 6707 O O   . HOH N 10 .   ? -10.58916 -9.55722  49.62850  1.000 47.69312 ? 370 HOH B O   1 
HETATM 6708 O O   . HOH N 10 .   ? 1.64666   -14.09725 35.72716  1.000 37.00862 ? 371 HOH B O   1 
HETATM 6709 O O   . HOH N 10 .   ? 23.37674  -2.94380  6.15094   1.000 41.96141 ? 372 HOH B O   1 
HETATM 6710 O O   . HOH N 10 .   ? -12.52370 -7.91120  35.57215  1.000 40.53518 ? 373 HOH B O   1 
HETATM 6711 O O   . HOH N 10 .   ? 4.54337   -9.86403  56.39137  1.000 44.45596 ? 374 HOH B O   1 
HETATM 6712 O O   . HOH N 10 .   ? 6.20507   -7.90387  15.93034  1.000 42.61800 ? 375 HOH B O   1 
HETATM 6713 O O   . HOH N 10 .   ? 10.87402  -17.58365 13.01744  1.000 45.11789 ? 376 HOH B O   1 
HETATM 6714 O O   . HOH N 10 .   ? 10.67648  -2.73864  1.36325   1.000 53.83480 ? 377 HOH B O   1 
HETATM 6715 O O   . HOH N 10 .   ? 28.367    -14.715   -0.021    1.000 43.26740 ? 378 HOH B O   1 
HETATM 6716 O O   . HOH N 10 .   ? 23.420    -14.103   -5.832    1.000 35.02604 ? 379 HOH B O   1 
HETATM 6717 O O   . HOH N 10 .   ? -10.77817 4.93562   52.46035  1.000 56.32229 ? 380 HOH B O   1 
HETATM 6718 O O   . HOH N 10 .   ? 6.53645   -10.51323 34.41642  1.000 30.37065 ? 381 HOH B O   1 
HETATM 6719 O O   . HOH N 10 .   ? 12.87889  -18.97699 12.82253  1.000 57.33192 ? 382 HOH B O   1 
HETATM 6720 O O   . HOH N 10 .   ? 5.99437   -10.75706 2.48617   1.000 48.31812 ? 383 HOH B O   1 
HETATM 6721 O O   . HOH N 10 .   ? -8.78707  6.95083   30.68982  1.000 42.59407 ? 384 HOH B O   1 
HETATM 6722 O O   . HOH N 10 .   ? -13.32808 -9.07373  43.61355  1.000 46.69686 ? 385 HOH B O   1 
HETATM 6723 O O   . HOH N 10 .   ? 17.32264  3.12657   12.74102  1.000 53.16461 ? 386 HOH B O   1 
HETATM 6724 O O   . HOH N 10 .   ? 4.21016   -16.79809 40.43103  1.000 49.25381 ? 387 HOH B O   1 
HETATM 6725 O O   . HOH N 10 .   ? 9.56141   -11.18291 21.21137  1.000 46.09292 ? 388 HOH B O   1 
HETATM 6726 O O   . HOH N 10 .   ? 35.82819  -26.21842 -8.15659  1.000 70.88424 ? 389 HOH B O   1 
HETATM 6727 O O   . HOH N 10 .   ? -4.06229  -12.31942 41.06633  1.000 23.42781 ? 390 HOH B O   1 
HETATM 6728 O O   . HOH N 10 .   ? 20.40163  -13.56120 23.01158  1.000 37.84059 ? 391 HOH B O   1 
HETATM 6729 O O   . HOH N 10 .   ? 14.12234  4.55482   11.14152  1.000 51.97125 ? 392 HOH B O   1 
HETATM 6730 O O   . HOH N 10 .   ? 29.92190  -15.08704 53.02208  1.000 56.49266 ? 393 HOH B O   1 
HETATM 6731 O O   . HOH N 10 .   ? 19.62777  -0.04422  11.79743  1.000 52.18825 ? 394 HOH B O   1 
HETATM 6732 O O   . HOH N 10 .   ? 12.66314  -20.10938 -4.59596  1.000 47.53132 ? 395 HOH B O   1 
HETATM 6733 O O   . HOH N 10 .   ? 28.074    -34.597   10.609    1.000 64.42020 ? 396 HOH B O   1 
HETATM 6734 O O   . HOH N 10 .   ? 25.09774  -15.15832 18.58315  1.000 54.19345 ? 397 HOH B O   1 
HETATM 6735 O O   . HOH O 10 .   ? -1.07295  17.33157  25.26467  1.000 60.39741 ? 501 HOH C O   1 
HETATM 6736 O O   . HOH O 10 .   ? 5.72711   3.04287   37.73195  1.000 23.82789 ? 502 HOH C O   1 
HETATM 6737 O O   . HOH O 10 .   ? 0.59832   -2.23728  44.77043  1.000 30.72503 ? 503 HOH C O   1 
HETATM 6738 O O   . HOH O 10 .   ? 3.89215   17.25203  28.10653  1.000 50.28588 ? 504 HOH C O   1 
HETATM 6739 O O   . HOH P 10 .   ? -37.04783 -35.59398 63.17615  1.000 57.54148 ? 401 HOH D O   1 
HETATM 6740 O O   . HOH P 10 .   ? -40.64437 -28.92809 65.15829  1.000 40.40130 ? 402 HOH D O   1 
HETATM 6741 O O   . HOH P 10 .   ? -38.31947 -25.17647 61.07763  1.000 37.84336 ? 403 HOH D O   1 
HETATM 6742 O O   . HOH P 10 .   ? -49.47401 -56.27956 57.38813  1.000 48.32370 ? 404 HOH D O   1 
HETATM 6743 O O   . HOH P 10 .   ? -19.66395 -13.93475 50.14505  1.000 37.79561 ? 405 HOH D O   1 
HETATM 6744 O O   . HOH P 10 .   ? -43.74373 -62.66767 61.22548  1.000 75.84776 ? 406 HOH D O   1 
HETATM 6745 O O   . HOH P 10 .   ? -19.87468 -11.27742 64.31049  1.000 51.49530 ? 407 HOH D O   1 
HETATM 6746 O O   . HOH P 10 .   ? -26.98830 -10.81774 53.30754  1.000 59.58865 ? 408 HOH D O   1 
HETATM 6747 O O   . HOH P 10 .   ? -22.38841 -9.37510  55.92863  1.000 52.38890 ? 409 HOH D O   1 
HETATM 6748 O O   . HOH P 10 .   ? -13.47173 -31.11758 47.51163  1.000 37.66524 ? 410 HOH D O   1 
HETATM 6749 O O   . HOH P 10 .   ? -44.54813 -53.54055 72.16504  1.000 38.08550 ? 411 HOH D O   1 
HETATM 6750 O O   . HOH P 10 .   ? -49.25436 -44.49093 68.96631  1.000 30.52395 ? 412 HOH D O   1 
HETATM 6751 O O   . HOH P 10 .   ? -42.67511 -37.82434 56.62664  1.000 23.79932 ? 413 HOH D O   1 
HETATM 6752 O O   . HOH P 10 .   ? -45.94088 -58.26447 49.13391  1.000 42.68308 ? 414 HOH D O   1 
HETATM 6753 O O   . HOH P 10 .   ? -11.13877 -30.94170 50.16012  1.000 32.23332 ? 415 HOH D O   1 
HETATM 6754 O O   . HOH P 10 .   ? -10.52326 -14.56609 65.32361  1.000 40.17907 ? 416 HOH D O   1 
HETATM 6755 O O   . HOH P 10 .   ? -3.23257  -16.73739 49.34958  1.000 31.66851 ? 417 HOH D O   1 
HETATM 6756 O O   . HOH P 10 .   ? -50.23818 -53.02514 45.43859  1.000 24.11584 ? 418 HOH D O   1 
HETATM 6757 O O   . HOH P 10 .   ? -41.74620 -41.89095 69.15912  1.000 31.68541 ? 419 HOH D O   1 
HETATM 6758 O O   . HOH P 10 .   ? -12.47669 -8.77428  60.15323  1.000 44.49859 ? 420 HOH D O   1 
HETATM 6759 O O   . HOH P 10 .   ? -5.81431  -23.08897 50.04347  1.000 45.50282 ? 421 HOH D O   1 
HETATM 6760 O O   . HOH P 10 .   ? -50.06532 -42.22617 64.12845  1.000 26.21185 ? 422 HOH D O   1 
HETATM 6761 O O   . HOH P 10 .   ? -22.48717 -13.08036 66.01678  1.000 49.45812 ? 423 HOH D O   1 
HETATM 6762 O O   . HOH P 10 .   ? -34.49694 -21.16656 68.92199  1.000 21.91898 ? 424 HOH D O   1 
HETATM 6763 O O   . HOH P 10 .   ? -21.49195 -35.39156 57.38900  1.000 32.24821 ? 425 HOH D O   1 
HETATM 6764 O O   . HOH P 10 .   ? -28.15399 -26.61550 46.79411  1.000 24.77885 ? 426 HOH D O   1 
HETATM 6765 O O   . HOH P 10 .   ? -45.06138 -38.19012 58.44583  1.000 32.13226 ? 427 HOH D O   1 
HETATM 6766 O O   . HOH P 10 .   ? -12.61575 -14.05527 53.65443  1.000 22.82349 ? 428 HOH D O   1 
HETATM 6767 O O   . HOH P 10 .   ? -11.19268 -24.98543 42.48257  1.000 18.52836 ? 429 HOH D O   1 
HETATM 6768 O O   . HOH P 10 .   ? -19.88689 -31.55890 47.76278  1.000 29.25946 ? 430 HOH D O   1 
HETATM 6769 O O   . HOH P 10 .   ? -31.17592 -30.32944 51.82952  1.000 37.95931 ? 431 HOH D O   1 
HETATM 6770 O O   . HOH P 10 .   ? -35.62603 -51.94439 60.14707  1.000 35.98219 ? 432 HOH D O   1 
HETATM 6771 O O   . HOH P 10 .   ? -45.55968 -26.12190 60.29774  1.000 42.79912 ? 433 HOH D O   1 
HETATM 6772 O O   . HOH P 10 .   ? -7.88026  -13.87996 62.51685  1.000 30.97166 ? 434 HOH D O   1 
HETATM 6773 O O   . HOH P 10 .   ? -30.83189 -21.14379 68.99300  1.000 32.79401 ? 435 HOH D O   1 
HETATM 6774 O O   . HOH P 10 .   ? -59.27205 -54.12671 59.06420  1.000 57.27986 ? 436 HOH D O   1 
HETATM 6775 O O   . HOH P 10 .   ? -51.24753 -46.96241 41.56394  1.000 26.96049 ? 437 HOH D O   1 
HETATM 6776 O O   . HOH P 10 .   ? -29.15752 -22.52352 55.79482  1.000 29.71900 ? 438 HOH D O   1 
HETATM 6777 O O   . HOH P 10 .   ? -14.71737 -29.78750 65.43289  1.000 37.50468 ? 439 HOH D O   1 
HETATM 6778 O O   . HOH P 10 .   ? -49.94619 -51.99020 50.80874  1.000 22.19569 ? 440 HOH D O   1 
HETATM 6779 O O   . HOH P 10 .   ? -16.00792 -18.70418 66.16931  1.000 37.27084 ? 441 HOH D O   1 
HETATM 6780 O O   . HOH P 10 .   ? -26.67826 -32.55413 51.26967  1.000 39.62991 ? 442 HOH D O   1 
HETATM 6781 O O   . HOH P 10 .   ? -24.71977 -21.30034 43.30810  1.000 17.71943 ? 443 HOH D O   1 
HETATM 6782 O O   . HOH P 10 .   ? -33.99163 -17.18544 57.68292  1.000 49.58431 ? 444 HOH D O   1 
HETATM 6783 O O   . HOH P 10 .   ? -45.75723 -51.85568 69.91852  1.000 30.56623 ? 445 HOH D O   1 
HETATM 6784 O O   . HOH P 10 .   ? -31.87867 -34.68199 63.00311  1.000 31.09119 ? 446 HOH D O   1 
HETATM 6785 O O   . HOH P 10 .   ? -45.33161 -51.16981 41.27913  1.000 32.01019 ? 447 HOH D O   1 
HETATM 6786 O O   . HOH P 10 .   ? -34.31457 -46.14958 67.62407  1.000 34.90112 ? 448 HOH D O   1 
HETATM 6787 O O   . HOH P 10 .   ? -54.06262 -57.24063 47.63897  1.000 38.27432 ? 449 HOH D O   1 
HETATM 6788 O O   . HOH P 10 .   ? -17.69778 -28.13318 59.01824  1.000 20.85323 ? 450 HOH D O   1 
HETATM 6789 O O   . HOH P 10 .   ? -38.70528 -53.60238 65.85344  1.000 40.61853 ? 451 HOH D O   1 
HETATM 6790 O O   . HOH P 10 .   ? -43.18858 -27.07885 65.24394  1.000 47.55535 ? 452 HOH D O   1 
HETATM 6791 O O   . HOH P 10 .   ? -18.58259 -28.56576 65.20957  1.000 28.91971 ? 453 HOH D O   1 
HETATM 6792 O O   . HOH P 10 .   ? -10.69839 -10.91479 58.10076  1.000 44.92748 ? 454 HOH D O   1 
HETATM 6793 O O   . HOH P 10 .   ? -16.14800 -33.75645 55.99444  1.000 35.72181 ? 455 HOH D O   1 
HETATM 6794 O O   . HOH P 10 .   ? -31.28591 -18.74322 70.12989  1.000 32.07142 ? 456 HOH D O   1 
HETATM 6795 O O   . HOH P 10 .   ? -34.69968 -38.49138 54.28099  1.000 37.75045 ? 457 HOH D O   1 
HETATM 6796 O O   . HOH P 10 .   ? -28.50053 -11.02320 64.03879  1.000 52.75407 ? 458 HOH D O   1 
HETATM 6797 O O   . HOH P 10 .   ? -25.97252 -28.12215 68.29666  1.000 24.55338 ? 459 HOH D O   1 
HETATM 6798 O O   . HOH P 10 .   ? -4.19690  -15.04555 47.20197  1.000 27.39221 ? 460 HOH D O   1 
HETATM 6799 O O   . HOH P 10 .   ? -51.17830 -57.99002 49.41168  1.000 41.14354 ? 461 HOH D O   1 
HETATM 6800 O O   . HOH P 10 .   ? -17.18083 -30.45321 48.07006  1.000 22.91303 ? 462 HOH D O   1 
HETATM 6801 O O   . HOH P 10 .   ? -12.74490 -31.69176 53.70956  1.000 29.06380 ? 463 HOH D O   1 
HETATM 6802 O O   . HOH P 10 .   ? -33.24337 -22.14127 55.84699  1.000 30.21268 ? 464 HOH D O   1 
HETATM 6803 O O   . HOH P 10 .   ? -45.36806 -31.31455 67.61674  1.000 37.01227 ? 465 HOH D O   1 
HETATM 6804 O O   . HOH P 10 .   ? -49.55020 -52.12651 68.85944  1.000 22.81437 ? 466 HOH D O   1 
HETATM 6805 O O   . HOH P 10 .   ? -45.38878 -56.04766 65.78871  1.000 35.72798 ? 467 HOH D O   1 
HETATM 6806 O O   . HOH P 10 .   ? -39.02978 -34.89803 68.43382  1.000 28.33554 ? 468 HOH D O   1 
HETATM 6807 O O   . HOH P 10 .   ? -43.54134 -37.54597 63.86359  1.000 23.13494 ? 469 HOH D O   1 
HETATM 6808 O O   . HOH P 10 .   ? -33.10547 -48.80137 64.99606  1.000 44.25866 ? 470 HOH D O   1 
HETATM 6809 O O   . HOH P 10 .   ? -57.39227 -52.17110 62.49611  1.000 39.60910 ? 471 HOH D O   1 
HETATM 6810 O O   . HOH P 10 .   ? -34.22307 -26.26738 52.02967  1.000 42.15127 ? 472 HOH D O   1 
HETATM 6811 O O   . HOH P 10 .   ? -25.29054 -34.78837 65.77406  1.000 35.43112 ? 473 HOH D O   1 
HETATM 6812 O O   . HOH P 10 .   ? -38.22932 -56.59269 57.12857  1.000 41.49140 ? 474 HOH D O   1 
HETATM 6813 O O   . HOH P 10 .   ? -54.34358 -47.88062 46.89678  1.000 29.13763 ? 475 HOH D O   1 
HETATM 6814 O O   . HOH P 10 .   ? -3.71375  -17.60646 57.99914  1.000 33.08289 ? 476 HOH D O   1 
HETATM 6815 O O   . HOH P 10 .   ? -22.85143 -27.83870 66.85598  1.000 26.03964 ? 477 HOH D O   1 
HETATM 6816 O O   . HOH P 10 .   ? -19.63763 -33.46305 49.71102  1.000 37.55016 ? 478 HOH D O   1 
HETATM 6817 O O   . HOH P 10 .   ? -5.07816  -24.61539 53.23991  1.000 27.77419 ? 479 HOH D O   1 
HETATM 6818 O O   . HOH P 10 .   ? -22.97516 -34.76420 52.45252  1.000 37.65636 ? 480 HOH D O   1 
HETATM 6819 O O   . HOH P 10 .   ? -39.70915 -57.02319 46.89938  1.000 37.78822 ? 481 HOH D O   1 
HETATM 6820 O O   . HOH P 10 .   ? -52.64434 -51.15796 59.19006  1.000 29.46391 ? 482 HOH D O   1 
HETATM 6821 O O   . HOH P 10 .   ? -24.60474 -33.02668 44.04273  1.000 25.44864 ? 483 HOH D O   1 
HETATM 6822 O O   . HOH P 10 .   ? -49.82934 -52.80188 61.60971  1.000 25.73535 ? 484 HOH D O   1 
HETATM 6823 O O   . HOH P 10 .   ? -34.98564 -57.09456 58.82855  1.000 53.76974 ? 485 HOH D O   1 
HETATM 6824 O O   . HOH P 10 .   ? -50.33297 -38.08892 64.85191  1.000 40.03186 ? 486 HOH D O   1 
HETATM 6825 O O   . HOH P 10 .   ? -38.48172 -52.59598 44.98192  1.000 39.96635 ? 487 HOH D O   1 
HETATM 6826 O O   . HOH P 10 .   ? -42.35381 -53.91366 62.30027  1.000 33.80629 ? 488 HOH D O   1 
HETATM 6827 O O   . HOH P 10 .   ? -1.66097  -18.78209 48.87253  1.000 27.65941 ? 489 HOH D O   1 
HETATM 6828 O O   . HOH P 10 .   ? -30.94782 -15.44688 58.66310  1.000 26.27584 ? 490 HOH D O   1 
HETATM 6829 O O   . HOH P 10 .   ? -41.07130 -54.53037 64.62963  1.000 36.05201 ? 491 HOH D O   1 
HETATM 6830 O O   . HOH P 10 .   ? -36.08906 -20.03471 63.27310  1.000 37.16985 ? 492 HOH D O   1 
HETATM 6831 O O   . HOH P 10 .   ? -36.31146 -54.26988 59.62468  1.000 34.99263 ? 493 HOH D O   1 
HETATM 6832 O O   . HOH P 10 .   ? -30.17584 -14.47032 65.31501  1.000 42.21360 ? 494 HOH D O   1 
HETATM 6833 O O   . HOH P 10 .   ? -36.56159 -35.03586 55.51701  1.000 36.19547 ? 495 HOH D O   1 
HETATM 6834 O O   . HOH P 10 .   ? -33.09604 -42.83477 58.48485  1.000 43.70026 ? 496 HOH D O   1 
HETATM 6835 O O   . HOH P 10 .   ? -47.87588 -36.90415 66.28082  1.000 37.12377 ? 497 HOH D O   1 
HETATM 6836 O O   . HOH P 10 .   ? -54.37165 -50.56638 57.67356  1.000 40.80704 ? 498 HOH D O   1 
HETATM 6837 O O   . HOH P 10 .   ? 1.36779   -22.82610 55.43760  1.000 36.48483 ? 499 HOH D O   1 
HETATM 6838 O O   . HOH P 10 .   ? -8.95931  -30.44037 51.04668  1.000 23.21189 ? 500 HOH D O   1 
HETATM 6839 O O   . HOH P 10 .   ? -0.673    -36.833   56.719    1.000 50.71954 ? 501 HOH D O   1 
HETATM 6840 O O   . HOH P 10 .   ? -5.12928  -25.33674 65.24130  1.000 38.24494 ? 502 HOH D O   1 
HETATM 6841 O O   . HOH P 10 .   ? -26.51184 -15.23703 54.67695  1.000 46.07885 ? 503 HOH D O   1 
HETATM 6842 O O   . HOH P 10 .   ? -32.97910 -43.05164 60.95575  1.000 43.45538 ? 504 HOH D O   1 
HETATM 6843 O O   . HOH P 10 .   ? -34.63963 -16.23675 64.75696  1.000 42.73027 ? 505 HOH D O   1 
HETATM 6844 O O   . HOH P 10 .   ? -33.33221 -29.53801 47.04618  1.000 47.69499 ? 506 HOH D O   1 
HETATM 6845 O O   . HOH P 10 .   ? -28.57355 -25.32141 48.96052  1.000 35.55583 ? 507 HOH D O   1 
HETATM 6846 O O   . HOH P 10 .   ? -13.09076 -33.05799 55.86772  1.000 26.84553 ? 508 HOH D O   1 
HETATM 6847 O O   . HOH P 10 .   ? -44.58452 -60.38998 40.99718  1.000 44.13842 ? 509 HOH D O   1 
HETATM 6848 O O   . HOH P 10 .   ? -38.098   -24.994   68.359    1.000 34.89012 ? 510 HOH D O   1 
HETATM 6849 O O   . HOH P 10 .   ? -6.52840  -17.62943 69.26066  1.000 40.66911 ? 511 HOH D O   1 
HETATM 6850 O O   . HOH P 10 .   ? -45.88713 -36.12651 64.42268  1.000 26.40706 ? 512 HOH D O   1 
HETATM 6851 O O   . HOH P 10 .   ? -46.21549 -54.87276 39.47536  1.000 31.54220 ? 513 HOH D O   1 
HETATM 6852 O O   . HOH P 10 .   ? -29.64656 -32.41820 51.65607  1.000 45.94738 ? 514 HOH D O   1 
HETATM 6853 O O   . HOH P 10 .   ? -48.42739 -44.02141 71.73412  1.000 38.92596 ? 515 HOH D O   1 
HETATM 6854 O O   . HOH P 10 .   ? -38.27169 -52.61802 68.59547  1.000 41.67657 ? 516 HOH D O   1 
HETATM 6855 O O   . HOH P 10 .   ? -41.68378 -56.20372 40.45109  1.000 46.31015 ? 517 HOH D O   1 
HETATM 6856 O O   . HOH P 10 .   ? -46.08179 -31.36876 64.96146  1.000 36.37846 ? 518 HOH D O   1 
HETATM 6857 O O   . HOH P 10 .   ? -38.20514 -24.40683 57.77979  1.000 32.53948 ? 519 HOH D O   1 
HETATM 6858 O O   . HOH P 10 .   ? -0.247    -35.234   58.331    1.000 46.51188 ? 520 HOH D O   1 
HETATM 6859 O O   . HOH P 10 .   ? -11.63206 -28.12533 45.23826  1.000 36.81892 ? 521 HOH D O   1 
HETATM 6860 O O   . HOH P 10 .   ? -21.34892 -12.41392 53.02122  1.000 38.54922 ? 522 HOH D O   1 
HETATM 6861 O O   . HOH P 10 .   ? -27.28776 -21.44390 42.20795  1.000 39.20964 ? 523 HOH D O   1 
HETATM 6862 O O   . HOH P 10 .   ? -20.98557 -8.18739  60.93669  1.000 58.57258 ? 524 HOH D O   1 
HETATM 6863 O O   . HOH P 10 .   ? -54.94750 -53.74375 50.77531  1.000 44.24457 ? 525 HOH D O   1 
HETATM 6864 O O   . HOH P 10 .   ? -23.96741 -13.07822 52.72336  1.000 50.35378 ? 526 HOH D O   1 
HETATM 6865 O O   . HOH P 10 .   ? -43.89938 -42.64135 71.72513  1.000 38.90689 ? 527 HOH D O   1 
HETATM 6866 O O   . HOH P 10 .   ? -51.33391 -26.31612 52.82652  1.000 56.28587 ? 528 HOH D O   1 
HETATM 6867 O O   . HOH P 10 .   ? -13.106   -19.668   63.958    1.000 26.96803 ? 529 HOH D O   1 
HETATM 6868 O O   . HOH P 10 .   ? -5.26987  -26.16479 62.39615  1.000 46.05765 ? 530 HOH D O   1 
HETATM 6869 O O   . HOH P 10 .   ? -32.12324 -34.24987 54.17671  1.000 53.56592 ? 531 HOH D O   1 
HETATM 6870 O O   . HOH P 10 .   ? -14.19656 -13.51492 51.99455  1.000 34.04245 ? 532 HOH D O   1 
HETATM 6871 O O   . HOH P 10 .   ? -9.02660  -27.82306 44.14625  1.000 37.80379 ? 533 HOH D O   1 
HETATM 6872 O O   . HOH P 10 .   ? -18.57733 -34.83064 63.42710  1.000 43.22381 ? 534 HOH D O   1 
HETATM 6873 O O   . HOH P 10 .   ? -7.38522  -26.90936 42.50418  1.000 45.85438 ? 535 HOH D O   1 
HETATM 6874 O O   . HOH P 10 .   ? -13.71584 -12.13442 49.98697  1.000 47.94424 ? 536 HOH D O   1 
HETATM 6875 O O   . HOH P 10 .   ? -22.61056 -13.52267 50.69716  1.000 40.92563 ? 537 HOH D O   1 
HETATM 6876 O O   . HOH P 10 .   ? -54.19897 -55.99547 51.38889  1.000 47.77518 ? 538 HOH D O   1 
HETATM 6877 O O   . HOH P 10 .   ? -31.56925 -46.18112 68.43501  1.000 50.58949 ? 539 HOH D O   1 
HETATM 6878 O O   . HOH P 10 .   ? -54.39931 -54.40086 53.02360  1.000 51.91141 ? 540 HOH D O   1 
HETATM 6879 O O   . HOH P 10 .   ? -7.823    -20.869   69.487    1.000 42.36543 ? 541 HOH D O   1 
HETATM 6880 O O   . HOH P 10 .   ? -39.55006 -54.81584 45.38801  1.000 46.08902 ? 542 HOH D O   1 
HETATM 6881 O O   . HOH P 10 .   ? -16.066   -30.024   67.327    1.000 34.43015 ? 543 HOH D O   1 
HETATM 6882 O O   . HOH P 10 .   ? -29.72577 -20.61416 53.88499  1.000 31.78297 ? 544 HOH D O   1 
HETATM 6883 O O   . HOH P 10 .   ? -31.75079 -33.95648 41.14036  1.000 48.04365 ? 545 HOH D O   1 
HETATM 6884 O O   . HOH P 10 .   ? -24.20581 -33.58994 48.92621  1.000 42.70073 ? 546 HOH D O   1 
HETATM 6885 O O   . HOH P 10 .   ? -35.99959 -57.05650 42.23910  1.000 56.05701 ? 547 HOH D O   1 
HETATM 6886 O O   . HOH P 10 .   ? -25.83858 -17.37890 45.25646  1.000 40.85824 ? 548 HOH D O   1 
HETATM 6887 O O   . HOH P 10 .   ? -28.78009 -15.79074 54.92009  1.000 52.83981 ? 549 HOH D O   1 
HETATM 6888 O O   . HOH P 10 .   ? -22.03019 -14.92136 68.10924  0.50  47.49923 ? 550 HOH D O   1 
HETATM 6889 O O   . HOH P 10 .   ? -42.27047 -54.27342 67.23896  1.000 41.72743 ? 551 HOH D O   1 
HETATM 6890 O O   . HOH P 10 .   ? -53.83642 -30.01046 51.40876  1.000 51.43991 ? 552 HOH D O   1 
HETATM 6891 O O   . HOH Q 10 .   ? -14.62485 -14.92306 29.58954  1.000 33.98868 ? 401 HOH E O   1 
HETATM 6892 O O   . HOH Q 10 .   ? -33.20641 -46.12528 18.23270  1.000 65.78781 ? 402 HOH E O   1 
HETATM 6893 O O   . HOH Q 10 .   ? -8.59085  -24.12853 42.16744  1.000 32.72347 ? 403 HOH E O   1 
HETATM 6894 O O   . HOH Q 10 .   ? -52.06598 -44.31477 55.63902  1.000 30.62801 ? 404 HOH E O   1 
HETATM 6895 O O   . HOH Q 10 .   ? -44.28848 -52.91932 39.69044  1.000 37.21122 ? 405 HOH E O   1 
HETATM 6896 O O   . HOH Q 10 .   ? -32.72724 -35.05551 46.51467  1.000 37.38491 ? 406 HOH E O   1 
HETATM 6897 O O   . HOH Q 10 .   ? -10.42171 -43.63997 29.02102  1.000 37.91967 ? 407 HOH E O   1 
HETATM 6898 O O   . HOH Q 10 .   ? -10.89235 -21.42624 24.96240  1.000 23.16454 ? 408 HOH E O   1 
HETATM 6899 O O   . HOH Q 10 .   ? -31.45210 -28.88972 35.42228  1.000 41.96638 ? 409 HOH E O   1 
HETATM 6900 O O   . HOH Q 10 .   ? -15.03908 -15.87415 26.81009  1.000 48.09980 ? 410 HOH E O   1 
HETATM 6901 O O   . HOH Q 10 .   ? -35.90653 -35.98261 47.11796  1.000 41.02746 ? 411 HOH E O   1 
HETATM 6902 O O   . HOH Q 10 .   ? -9.14781  -32.19216 43.61697  1.000 44.46748 ? 412 HOH E O   1 
HETATM 6903 O O   . HOH Q 10 .   ? -52.64804 -35.90845 64.01615  1.000 35.69495 ? 413 HOH E O   1 
HETATM 6904 O O   . HOH Q 10 .   ? -8.22225  -25.49417 27.35895  1.000 30.25284 ? 414 HOH E O   1 
HETATM 6905 O O   . HOH Q 10 .   ? -15.84764 -19.29796 37.43277  1.000 22.53122 ? 415 HOH E O   1 
HETATM 6906 O O   . HOH Q 10 .   ? -40.68367 -34.38292 45.38611  1.000 28.45329 ? 416 HOH E O   1 
HETATM 6907 O O   . HOH Q 10 .   ? -11.55964 -34.11237 25.46402  1.000 26.31970 ? 417 HOH E O   1 
HETATM 6908 O O   . HOH Q 10 .   ? -58.86867 -43.71403 44.02948  1.000 33.55780 ? 418 HOH E O   1 
HETATM 6909 O O   . HOH Q 10 .   ? -15.28115 -9.08427  34.46357  1.000 37.06351 ? 419 HOH E O   1 
HETATM 6910 O O   . HOH Q 10 .   ? -27.86378 -18.30175 30.98559  1.000 37.79696 ? 420 HOH E O   1 
HETATM 6911 O O   . HOH Q 10 .   ? -19.59876 -10.08073 48.96599  1.000 47.01673 ? 421 HOH E O   1 
HETATM 6912 O O   . HOH Q 10 .   ? -4.91788  -14.93806 42.19471  1.000 31.18485 ? 422 HOH E O   1 
HETATM 6913 O O   . HOH Q 10 .   ? -44.63970 -43.10401 29.94983  1.000 35.09316 ? 423 HOH E O   1 
HETATM 6914 O O   . HOH Q 10 .   ? -19.22759 -34.57771 21.72858  1.000 39.37182 ? 424 HOH E O   1 
HETATM 6915 O O   . HOH Q 10 .   ? -26.65390 -10.07246 35.22939  1.000 26.21338 ? 425 HOH E O   1 
HETATM 6916 O O   . HOH Q 10 .   ? -67.90943 -39.82466 53.32507  1.000 49.56172 ? 426 HOH E O   1 
HETATM 6917 O O   . HOH Q 10 .   ? -11.92650 -12.02641 41.36141  1.000 24.91598 ? 427 HOH E O   1 
HETATM 6918 O O   . HOH Q 10 .   ? -28.18275 -24.55183 35.12695  1.000 34.15462 ? 428 HOH E O   1 
HETATM 6919 O O   . HOH Q 10 .   ? -41.14885 -32.98309 33.72505  1.000 30.50047 ? 429 HOH E O   1 
HETATM 6920 O O   . HOH Q 10 .   ? -43.05528 -47.06172 30.62364  1.000 38.87688 ? 430 HOH E O   1 
HETATM 6921 O O   . HOH Q 10 .   ? -53.91803 -47.25730 44.18690  1.000 30.55794 ? 431 HOH E O   1 
HETATM 6922 O O   . HOH Q 10 .   ? -43.18267 -31.04557 53.68224  1.000 27.52475 ? 432 HOH E O   1 
HETATM 6923 O O   . HOH Q 10 .   ? -15.22556 -11.57667 44.99816  1.000 34.32049 ? 433 HOH E O   1 
HETATM 6924 O O   . HOH Q 10 .   ? -23.84928 -19.28611 44.66476  1.000 17.85617 ? 434 HOH E O   1 
HETATM 6925 O O   . HOH Q 10 .   ? -25.68310 -42.90849 23.71753  1.000 38.20753 ? 435 HOH E O   1 
HETATM 6926 O O   . HOH Q 10 .   ? -23.12901 -28.51161 31.19743  1.000 25.05530 ? 436 HOH E O   1 
HETATM 6927 O O   . HOH Q 10 .   ? -67.10697 -36.84498 51.80035  1.000 38.09004 ? 437 HOH E O   1 
HETATM 6928 O O   . HOH Q 10 .   ? -26.36504 -40.49796 38.49637  1.000 38.26250 ? 438 HOH E O   1 
HETATM 6929 O O   . HOH Q 10 .   ? -41.95089 -34.67591 38.06907  1.000 24.40069 ? 439 HOH E O   1 
HETATM 6930 O O   . HOH Q 10 .   ? -30.74815 -39.55847 30.95375  1.000 34.51573 ? 440 HOH E O   1 
HETATM 6931 O O   . HOH Q 10 .   ? -30.86807 -26.53106 30.96170  1.000 48.79132 ? 441 HOH E O   1 
HETATM 6932 O O   . HOH Q 10 .   ? -30.26813 -52.20414 34.96732  1.000 45.25987 ? 442 HOH E O   1 
HETATM 6933 O O   . HOH Q 10 .   ? -54.07378 -33.49868 40.08406  1.000 27.53376 ? 443 HOH E O   1 
HETATM 6934 O O   . HOH Q 10 .   ? -43.69564 -49.06917 41.79022  1.000 23.24560 ? 444 HOH E O   1 
HETATM 6935 O O   . HOH Q 10 .   ? -8.50247  -31.36109 40.31119  1.000 25.25983 ? 445 HOH E O   1 
HETATM 6936 O O   . HOH Q 10 .   ? -47.38335 -39.64982 57.54449  1.000 20.09143 ? 446 HOH E O   1 
HETATM 6937 O O   . HOH Q 10 .   ? -36.25270 -40.59049 53.00163  1.000 36.63624 ? 447 HOH E O   1 
HETATM 6938 O O   . HOH Q 10 .   ? -40.78931 -52.51534 39.66842  1.000 35.35091 ? 448 HOH E O   1 
HETATM 6939 O O   . HOH Q 10 .   ? -12.93894 -19.33543 40.82251  1.000 26.56387 ? 449 HOH E O   1 
HETATM 6940 O O   . HOH Q 10 .   ? -36.36512 -34.94857 51.81379  1.000 36.67620 ? 450 HOH E O   1 
HETATM 6941 O O   . HOH Q 10 .   ? -26.84401 -49.04089 39.90871  1.000 39.48014 ? 451 HOH E O   1 
HETATM 6942 O O   . HOH Q 10 .   ? -6.38282  -38.82610 28.70233  1.000 36.12711 ? 452 HOH E O   1 
HETATM 6943 O O   . HOH Q 10 .   ? -23.20875 -29.52654 24.94116  1.000 31.85450 ? 453 HOH E O   1 
HETATM 6944 O O   . HOH Q 10 .   ? -54.02483 -37.23009 35.73778  1.000 51.27935 ? 454 HOH E O   1 
HETATM 6945 O O   . HOH Q 10 .   ? -21.09221 -37.04101 46.27329  1.000 43.76030 ? 455 HOH E O   1 
HETATM 6946 O O   . HOH Q 10 .   ? -15.92385 -35.59052 42.45081  1.000 38.41625 ? 456 HOH E O   1 
HETATM 6947 O O   . HOH Q 10 .   ? -40.54831 -47.14913 27.63118  1.000 37.06906 ? 457 HOH E O   1 
HETATM 6948 O O   . HOH Q 10 .   ? -14.32127 -47.13194 35.19206  1.000 35.80759 ? 458 HOH E O   1 
HETATM 6949 O O   . HOH Q 10 .   ? -51.00456 -31.21132 52.64907  1.000 37.08450 ? 459 HOH E O   1 
HETATM 6950 O O   . HOH Q 10 .   ? -28.89598 -32.27407 36.08301  1.000 31.54339 ? 460 HOH E O   1 
HETATM 6951 O O   . HOH Q 10 .   ? -13.20260 -13.74922 45.82194  1.000 24.37811 ? 461 HOH E O   1 
HETATM 6952 O O   . HOH Q 10 .   ? -72.912   -45.482   51.276    1.000 34.56614 ? 462 HOH E O   1 
HETATM 6953 O O   . HOH Q 10 .   ? -13.41649 -21.64336 40.20134  1.000 22.75487 ? 463 HOH E O   1 
HETATM 6954 O O   . HOH Q 10 .   ? -22.12376 -46.94072 35.45371  1.000 46.72083 ? 464 HOH E O   1 
HETATM 6955 O O   . HOH Q 10 .   ? -13.77791 -17.25356 39.21593  1.000 19.94731 ? 465 HOH E O   1 
HETATM 6956 O O   . HOH Q 10 .   ? -7.52787  -15.39111 31.25557  1.000 31.59305 ? 466 HOH E O   1 
HETATM 6957 O O   . HOH Q 10 .   ? -43.749   -52.509   32.938    1.000 38.45821 ? 467 HOH E O   1 
HETATM 6958 O O   . HOH Q 10 .   ? -44.28242 -39.23659 28.55646  1.000 31.07900 ? 468 HOH E O   1 
HETATM 6959 O O   . HOH Q 10 .   ? -44.72088 -55.06647 35.04296  1.000 30.39814 ? 469 HOH E O   1 
HETATM 6960 O O   . HOH Q 10 .   ? -37.50700 -36.17043 42.85614  1.000 25.74303 ? 470 HOH E O   1 
HETATM 6961 O O   . HOH Q 10 .   ? -14.06686 -11.63861 42.98444  1.000 37.43320 ? 471 HOH E O   1 
HETATM 6962 O O   . HOH Q 10 .   ? -10.28937 -29.73753 43.33280  1.000 27.73123 ? 472 HOH E O   1 
HETATM 6963 O O   . HOH Q 10 .   ? -19.75084 -12.28433 40.46436  1.000 32.89860 ? 473 HOH E O   1 
HETATM 6964 O O   . HOH Q 10 .   ? -7.73766  -31.76730 32.06601  1.000 31.33044 ? 474 HOH E O   1 
HETATM 6965 O O   . HOH Q 10 .   ? -8.05084  -30.83459 35.03947  1.000 25.93079 ? 475 HOH E O   1 
HETATM 6966 O O   . HOH Q 10 .   ? -44.20136 -31.93233 44.17178  1.000 24.69214 ? 476 HOH E O   1 
HETATM 6967 O O   . HOH Q 10 .   ? -48.11339 -43.12952 33.20111  1.000 30.70134 ? 477 HOH E O   1 
HETATM 6968 O O   . HOH Q 10 .   ? -12.95439 -44.93183 22.23740  1.000 36.62493 ? 478 HOH E O   1 
HETATM 6969 O O   . HOH Q 10 .   ? -27.37526 -44.04763 38.05294  1.000 36.50131 ? 479 HOH E O   1 
HETATM 6970 O O   . HOH Q 10 .   ? -55.35367 -45.37136 43.48570  1.000 36.40847 ? 480 HOH E O   1 
HETATM 6971 O O   . HOH Q 10 .   ? -53.32735 -45.82266 40.81800  1.000 32.40391 ? 481 HOH E O   1 
HETATM 6972 O O   . HOH Q 10 .   ? -14.69184 -48.29796 32.21688  1.000 38.09651 ? 482 HOH E O   1 
HETATM 6973 O O   . HOH Q 10 .   ? -25.02711 -35.21727 42.79666  1.000 31.78603 ? 483 HOH E O   1 
HETATM 6974 O O   . HOH Q 10 .   ? -28.96243 -39.23659 27.00085  1.000 35.68142 ? 484 HOH E O   1 
HETATM 6975 O O   . HOH Q 10 .   ? -23.93720 -15.85771 21.25617  1.000 38.45129 ? 485 HOH E O   1 
HETATM 6976 O O   . HOH Q 10 .   ? -3.85810  -23.25995 32.63445  1.000 40.97555 ? 486 HOH E O   1 
HETATM 6977 O O   . HOH Q 10 .   ? -26.65215 -7.20234  31.96804  1.000 24.62671 ? 487 HOH E O   1 
HETATM 6978 O O   . HOH Q 10 .   ? -13.25868 -5.65957  36.72557  1.000 51.02953 ? 488 HOH E O   1 
HETATM 6979 O O   . HOH Q 10 .   ? -22.82643 -50.67157 33.14030  1.000 48.58099 ? 489 HOH E O   1 
HETATM 6980 O O   . HOH Q 10 .   ? -32.48672 -36.42324 39.37655  1.000 33.54457 ? 490 HOH E O   1 
HETATM 6981 O O   . HOH Q 10 .   ? -42.90978 -48.23778 33.09313  1.000 26.50916 ? 491 HOH E O   1 
HETATM 6982 O O   . HOH Q 10 .   ? -16.20814 -11.68805 40.79193  1.000 29.37372 ? 492 HOH E O   1 
HETATM 6983 O O   . HOH Q 10 .   ? -57.17217 -46.61646 64.39886  1.000 37.81316 ? 493 HOH E O   1 
HETATM 6984 O O   . HOH Q 10 .   ? -34.83467 -44.17643 48.44020  1.000 38.20375 ? 494 HOH E O   1 
HETATM 6985 O O   . HOH Q 10 .   ? -31.13194 -38.36960 28.92223  1.000 34.79594 ? 495 HOH E O   1 
HETATM 6986 O O   . HOH Q 10 .   ? -39.79813 -54.36280 34.42445  1.000 49.81876 ? 496 HOH E O   1 
HETATM 6987 O O   . HOH Q 10 .   ? -5.10121  -16.68897 31.07982  1.000 42.38185 ? 497 HOH E O   1 
HETATM 6988 O O   . HOH Q 10 .   ? -41.09433 -36.81323 28.90291  1.000 32.96021 ? 498 HOH E O   1 
HETATM 6989 O O   . HOH Q 10 .   ? -42.22979 -29.90538 38.26842  1.000 49.81249 ? 499 HOH E O   1 
HETATM 6990 O O   . HOH Q 10 .   ? -31.85015 -54.61942 39.83516  1.000 44.26003 ? 500 HOH E O   1 
HETATM 6991 O O   . HOH Q 10 .   ? -3.74033  -36.58512 35.44606  1.000 46.75769 ? 501 HOH E O   1 
HETATM 6992 O O   . HOH Q 10 .   ? -53.19953 -34.03158 37.87849  1.000 42.71996 ? 502 HOH E O   1 
HETATM 6993 O O   . HOH Q 10 .   ? -25.97387 -29.10752 25.10088  1.000 45.17257 ? 503 HOH E O   1 
HETATM 6994 O O   . HOH Q 10 .   ? -57.94258 -40.03193 67.80337  1.000 58.53656 ? 504 HOH E O   1 
HETATM 6995 O O   . HOH Q 10 .   ? -3.18181  -24.22056 36.92601  1.000 41.54985 ? 505 HOH E O   1 
HETATM 6996 O O   . HOH Q 10 .   ? -39.21232 -33.39561 49.61807  1.000 36.89345 ? 506 HOH E O   1 
HETATM 6997 O O   . HOH Q 10 .   ? -61.52500 -30.05559 49.98034  1.000 43.79105 ? 507 HOH E O   1 
HETATM 6998 O O   . HOH Q 10 .   ? -31.50338 -30.75284 28.80858  1.000 36.61934 ? 508 HOH E O   1 
HETATM 6999 O O   . HOH Q 10 .   ? -48.09255 -26.33021 48.17481  1.000 34.52714 ? 509 HOH E O   1 
HETATM 7000 O O   . HOH Q 10 .   ? -9.69407  -18.30569 43.54941  1.000 34.79934 ? 510 HOH E O   1 
HETATM 7001 O O   . HOH Q 10 .   ? -22.79746 -10.72396 40.31774  1.000 46.58170 ? 511 HOH E O   1 
HETATM 7002 O O   . HOH Q 10 .   ? -53.19075 -44.82603 38.40787  1.000 27.37313 ? 512 HOH E O   1 
HETATM 7003 O O   . HOH Q 10 .   ? -57.51766 -45.97925 67.07688  1.000 45.24948 ? 513 HOH E O   1 
HETATM 7004 O O   . HOH Q 10 .   ? -8.39669  -28.08258 27.54215  1.000 32.37695 ? 514 HOH E O   1 
HETATM 7005 O O   . HOH Q 10 .   ? -59.67653 -33.52349 58.81495  1.000 35.05927 ? 515 HOH E O   1 
HETATM 7006 O O   . HOH Q 10 .   ? -25.87744 -23.85412 27.53932  1.000 38.89677 ? 516 HOH E O   1 
HETATM 7007 O O   . HOH Q 10 .   ? -29.31889 -33.36600 38.31697  1.000 39.21356 ? 517 HOH E O   1 
HETATM 7008 O O   . HOH Q 10 .   ? -2.45208  -28.88806 37.76265  1.000 50.37157 ? 518 HOH E O   1 
HETATM 7009 O O   . HOH Q 10 .   ? -3.89345  -27.06364 29.45733  1.000 35.74961 ? 519 HOH E O   1 
HETATM 7010 O O   . HOH Q 10 .   ? -50.96577 -29.95924 49.81682  1.000 49.35819 ? 520 HOH E O   1 
HETATM 7011 O O   . HOH Q 10 .   ? -7.23380  -29.51923 41.82824  1.000 35.72511 ? 521 HOH E O   1 
HETATM 7012 O O   . HOH Q 10 .   ? -55.06663 -30.80068 53.87309  1.000 32.73457 ? 522 HOH E O   1 
HETATM 7013 O O   . HOH Q 10 .   ? -28.68104 -48.01501 48.30260  1.000 47.47154 ? 523 HOH E O   1 
HETATM 7014 O O   . HOH Q 10 .   ? -23.29522 -9.55083  38.30332  1.000 42.35109 ? 524 HOH E O   1 
HETATM 7015 O O   . HOH Q 10 .   ? -31.63993 -33.47558 29.28522  1.000 35.74310 ? 525 HOH E O   1 
HETATM 7016 O O   . HOH Q 10 .   ? -18.33691 -35.75267 49.63970  1.000 40.51669 ? 526 HOH E O   1 
HETATM 7017 O O   . HOH Q 10 .   ? -27.654   -16.178   30.093    1.000 40.49906 ? 527 HOH E O   1 
HETATM 7018 O O   . HOH Q 10 .   ? -57.34354 -48.41069 46.50411  1.000 46.73170 ? 528 HOH E O   1 
HETATM 7019 O O   . HOH Q 10 .   ? -24.22260 -40.83590 37.75646  1.000 39.42070 ? 529 HOH E O   1 
HETATM 7020 O O   . HOH Q 10 .   ? -32.31346 -36.42714 28.67826  1.000 35.92488 ? 530 HOH E O   1 
HETATM 7021 O O   . HOH Q 10 .   ? -39.06110 -30.92393 33.27492  1.000 47.95433 ? 531 HOH E O   1 
HETATM 7022 O O   . HOH Q 10 .   ? -60.68437 -48.01928 61.83807  1.000 49.49628 ? 532 HOH E O   1 
HETATM 7023 O O   . HOH Q 10 .   ? -8.92676  -23.49743 25.19826  1.000 38.89467 ? 533 HOH E O   1 
HETATM 7024 O O   . HOH Q 10 .   ? -52.54617 -42.68711 35.53468  1.000 50.54607 ? 534 HOH E O   1 
HETATM 7025 O O   . HOH Q 10 .   ? -23.75674 -37.08859 42.65717  1.000 47.19358 ? 535 HOH E O   1 
HETATM 7026 O O   . HOH Q 10 .   ? -41.82946 -50.70526 32.59389  1.000 47.33654 ? 536 HOH E O   1 
HETATM 7027 O O   . HOH Q 10 .   ? -30.25915 -55.44125 36.54806  1.000 59.01972 ? 537 HOH E O   1 
HETATM 7028 O O   . HOH Q 10 .   ? -41.18668 -30.90735 48.67692  1.000 51.74010 ? 538 HOH E O   1 
HETATM 7029 O O   . HOH Q 10 .   ? -37.67455 -34.42134 45.08134  1.000 36.79863 ? 539 HOH E O   1 
HETATM 7030 O O   . HOH Q 10 .   ? -43.61865 -45.02326 26.08242  1.000 52.23840 ? 540 HOH E O   1 
HETATM 7031 O O   . HOH Q 10 .   ? -35.13117 -37.08099 43.43882  1.000 49.12773 ? 541 HOH E O   1 
HETATM 7032 O O   . HOH Q 10 .   ? -26.94689 -36.53889 50.11037  1.000 47.12411 ? 542 HOH E O   1 
HETATM 7033 O O   . HOH Q 10 .   ? -42.05177 -32.24810 45.65560  1.000 32.90867 ? 543 HOH E O   1 
HETATM 7034 O O   . HOH Q 10 .   ? -35.34488 -36.17366 53.73564  1.000 41.35455 ? 544 HOH E O   1 
HETATM 7035 O O   . HOH Q 10 .   ? -19.814   -19.171   19.795    1.000 45.56330 ? 545 HOH E O   1 
HETATM 7036 O O   . HOH Q 10 .   ? -42.25824 -48.79669 28.85903  1.000 34.46944 ? 546 HOH E O   1 
HETATM 7037 O O   . HOH Q 10 .   ? -45.55585 -48.26013 33.46806  1.000 34.73276 ? 547 HOH E O   1 
HETATM 7038 O O   . HOH Q 10 .   ? -38.61926 -31.60061 29.98202  1.000 60.84420 ? 548 HOH E O   1 
HETATM 7039 O O   . HOH Q 10 .   ? -41.10343 -50.66720 29.55812  1.000 43.42393 ? 549 HOH E O   1 
HETATM 7040 O O   . HOH Q 10 .   ? -28.09977 -19.29831 42.85607  1.000 47.87463 ? 550 HOH E O   1 
HETATM 7041 O O   . HOH Q 10 .   ? -53.54070 -28.13999 47.56046  1.000 42.76157 ? 551 HOH E O   1 
HETATM 7042 O O   . HOH Q 10 .   ? -53.23691 -30.60478 49.28662  1.000 38.46688 ? 552 HOH E O   1 
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