data_9EBO
# 
_entry.id   9EBO 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9EBO         pdb_00009ebo 10.2210/pdb9ebo/pdb 
WWPDB D_1000289746 ?            ?                   
EMDB  EMD-47883    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-03-26 ? 
2  'EM metadata'     1 0 2025-03-26 ? 
3  'Additional map'  1 0 2025-03-26 1 
4  'Additional map'  1 0 2025-03-26 2 
5  'Additional map'  1 0 2025-03-26 3 
6  FSC               1 0 2025-03-26 ? 
7  'Half map'        1 0 2025-03-26 1 
8  'Half map'        1 0 2025-03-26 2 
9  Image             1 0 2025-03-26 ? 
10 Mask              1 0 2025-03-26 1 
11 'Primary map'     1 0 2025-03-26 ? 
12 'Structure model' 1 1 2025-04-16 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  'Additional map'  repository 'Initial release' ? ? 
4  4  'Additional map'  repository 'Initial release' ? ? 
5  5  'Additional map'  repository 'Initial release' ? ? 
6  6  FSC               repository 'Initial release' ? ? 
7  7  'Half map'        repository 'Initial release' ? ? 
8  8  'Half map'        repository 'Initial release' ? ? 
9  9  Image             repository 'Initial release' ? ? 
10 10 Mask              repository 'Initial release' ? ? 
11 11 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 12 'Structure model' 'Data collection'     
2 12 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 12 'Structure model' citation        
2 12 'Structure model' citation_author 
3 12 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  12 'Structure model' '_citation.country'                 
2  12 'Structure model' '_citation.journal_abbrev'          
3  12 'Structure model' '_citation.journal_id_ASTM'         
4  12 'Structure model' '_citation.journal_id_CSD'          
5  12 'Structure model' '_citation.journal_id_ISSN'         
6  12 'Structure model' '_citation.journal_volume'          
7  12 'Structure model' '_citation.page_first'              
8  12 'Structure model' '_citation.page_last'               
9  12 'Structure model' '_citation.pdbx_database_id_DOI'    
10 12 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 12 'Structure model' '_citation.title'                   
12 12 'Structure model' '_citation.year'                    
13 12 'Structure model' '_citation_author.identifier_ORCID' 
14 12 'Structure model' '_citation_author.name'             
15 12 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9EBO 
_pdbx_database_status.recvd_initial_deposition_date   2024-11-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 1)' 
_pdbx_database_related.db_id          EMD-47883 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 gellman@chem.wisc.edu     Samuel  Gellman H 'principal investigator/group leader' 0000-0001-5617-0058 
3 patrick.sexton@monash.edu Patrick Sexton  M 'principal investigator/group leader' 0000-0001-8902-2473 
4 denise.wootten@monash.edu Denise  Wootten ? 'principal investigator/group leader' 0000-0003-4563-1642 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Cary, B.P.'      1 0000-0001-9523-2522 
'Hager, M.V.'     2 0000-0001-8050-4943 
'Mariam, Z.'      3 0000-0002-4563-9559 
'Morris, R.K.'    4 0000-0001-5305-6006 
'Belousoff, M.J.' 5 0000-0002-3229-474X 
'Deganutti, G.'   6 0000-0001-8780-2986 
'Wootten, D.'     7 0000-0003-4563-1642 
'Sexton, P.M.'    8 0000-0002-6813-1336 
'Gellman, S.H.'   9 0000-0001-5617-0058 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            122 
_citation.language                  ? 
_citation.page_first                e2407574122 
_citation.page_last                 e2407574122 
_citation.title                     
'Prolonged signaling of backbone-modified glucagon-like peptide- 1 analogues with diverse receptor trafficking.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2407574122 
_citation.pdbx_database_id_PubMed   40168114 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cary, B.P.'      1 0000-0001-9523-2522 
primary 'Hager, M.V.'     2 ?                   
primary 'Mariam, Z.'      3 ?                   
primary 'Morris, R.K.'    4 ?                   
primary 'Belousoff, M.J.' 5 ?                   
primary 'Deganutti, G.'   6 0000-0001-8780-2986 
primary 'Sexton, P.M.'    7 0000-0001-8902-2473 
primary 'Wootten, D.'     8 ?                   
primary 'Gellman, S.H.'   9 0000-0001-5617-0058 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Guanine nucleotide-binding protein G(s) subunit alpha isoforms short' 45683.434 1 ? ? ? ? 
2 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'     37413.863 1 ? ? ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'    6375.332  1 ? ? ? ? 
4 polymer man Nanobody35                                                             13885.439 1 ? ? ? ? 
5 polymer syn 'Glucagon-like peptide 1(7-36)'                                        3326.712  1 ? ? ? ? 
6 polymer man 'Glucagon-like peptide 1 receptor'                                     56748.418 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-stimulating G alpha protein' 
2 'Transducin beta chain 1'                       
3 'G gamma-I'                                     
5 'GLP-1(7-36)'                                   
6 GLP-1R                                          
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKNTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQAALKLFDSIWNNKWLRDTSVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKNTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQAALKLFDSIWNNKWLRDTSVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
A ? 
2 'polypeptide(L)' no no  
;QSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
;
;QSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLI
IWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS
SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV
TDDGMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no  NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR 
NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR G ? 
4 'polypeptide(L)' no no  
;QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLY
LQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSS
;
;QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLY
LQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSS
;
N ? 
5 'polypeptide(L)' no yes 'HAEGTFTSDVS(XCP)YLEGQAAKEFIAWLVKGR' HAEGTFTSDVSXYLEGQAAKEFIAWLVKGR P ? 
6 'polypeptide(L)' no no  
;MKTIIALSYIFCLVFADYKDDDDLEVLFQGPARPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYAC
WPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVG
YALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFL
LMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRL
PILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFT
SFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCSPAGLEVLF
QGPHHHHHHHH
;
;MKTIIALSYIFCLVFADYKDDDDLEVLFQGPARPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYAC
WPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVG
YALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFL
LMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRL
PILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFT
SFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCSPAGLEVLF
QGPHHHHHHHH
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   LEU n 
1 5   GLY n 
1 6   ASN n 
1 7   SER n 
1 8   LYS n 
1 9   THR n 
1 10  GLU n 
1 11  ASP n 
1 12  GLN n 
1 13  ARG n 
1 14  ASN n 
1 15  GLU n 
1 16  GLU n 
1 17  LYS n 
1 18  ALA n 
1 19  GLN n 
1 20  ARG n 
1 21  GLU n 
1 22  ALA n 
1 23  ASN n 
1 24  LYS n 
1 25  LYS n 
1 26  ILE n 
1 27  GLU n 
1 28  LYS n 
1 29  GLN n 
1 30  LEU n 
1 31  GLN n 
1 32  LYS n 
1 33  ASP n 
1 34  LYS n 
1 35  GLN n 
1 36  VAL n 
1 37  TYR n 
1 38  ARG n 
1 39  ALA n 
1 40  THR n 
1 41  HIS n 
1 42  ARG n 
1 43  LEU n 
1 44  LEU n 
1 45  LEU n 
1 46  LEU n 
1 47  GLY n 
1 48  ALA n 
1 49  GLY n 
1 50  GLU n 
1 51  SER n 
1 52  GLY n 
1 53  LYS n 
1 54  ASN n 
1 55  THR n 
1 56  ILE n 
1 57  VAL n 
1 58  LYS n 
1 59  GLN n 
1 60  MET n 
1 61  ARG n 
1 62  ILE n 
1 63  LEU n 
1 64  HIS n 
1 65  VAL n 
1 66  ASN n 
1 67  GLY n 
1 68  PHE n 
1 69  ASN n 
1 70  GLY n 
1 71  GLU n 
1 72  GLY n 
1 73  GLY n 
1 74  GLU n 
1 75  GLU n 
1 76  ASP n 
1 77  PRO n 
1 78  GLN n 
1 79  ALA n 
1 80  ALA n 
1 81  ARG n 
1 82  SER n 
1 83  ASN n 
1 84  SER n 
1 85  ASP n 
1 86  GLY n 
1 87  GLU n 
1 88  LYS n 
1 89  ALA n 
1 90  THR n 
1 91  LYS n 
1 92  VAL n 
1 93  GLN n 
1 94  ASP n 
1 95  ILE n 
1 96  LYS n 
1 97  ASN n 
1 98  ASN n 
1 99  LEU n 
1 100 LYS n 
1 101 GLU n 
1 102 ALA n 
1 103 ILE n 
1 104 GLU n 
1 105 THR n 
1 106 ILE n 
1 107 VAL n 
1 108 ALA n 
1 109 ALA n 
1 110 MET n 
1 111 SER n 
1 112 ASN n 
1 113 LEU n 
1 114 VAL n 
1 115 PRO n 
1 116 PRO n 
1 117 VAL n 
1 118 GLU n 
1 119 LEU n 
1 120 ALA n 
1 121 ASN n 
1 122 PRO n 
1 123 GLU n 
1 124 ASN n 
1 125 GLN n 
1 126 PHE n 
1 127 ARG n 
1 128 VAL n 
1 129 ASP n 
1 130 TYR n 
1 131 ILE n 
1 132 LEU n 
1 133 SER n 
1 134 VAL n 
1 135 MET n 
1 136 ASN n 
1 137 VAL n 
1 138 PRO n 
1 139 ASP n 
1 140 PHE n 
1 141 ASP n 
1 142 PHE n 
1 143 PRO n 
1 144 PRO n 
1 145 GLU n 
1 146 PHE n 
1 147 TYR n 
1 148 GLU n 
1 149 HIS n 
1 150 ALA n 
1 151 LYS n 
1 152 ALA n 
1 153 LEU n 
1 154 TRP n 
1 155 GLU n 
1 156 ASP n 
1 157 GLU n 
1 158 GLY n 
1 159 VAL n 
1 160 ARG n 
1 161 ALA n 
1 162 CYS n 
1 163 TYR n 
1 164 GLU n 
1 165 ARG n 
1 166 SER n 
1 167 ASN n 
1 168 GLU n 
1 169 TYR n 
1 170 GLN n 
1 171 LEU n 
1 172 ILE n 
1 173 ASP n 
1 174 CYS n 
1 175 ALA n 
1 176 GLN n 
1 177 TYR n 
1 178 PHE n 
1 179 LEU n 
1 180 ASP n 
1 181 LYS n 
1 182 ILE n 
1 183 ASP n 
1 184 VAL n 
1 185 ILE n 
1 186 LYS n 
1 187 GLN n 
1 188 ALA n 
1 189 ASP n 
1 190 TYR n 
1 191 VAL n 
1 192 PRO n 
1 193 SER n 
1 194 ASP n 
1 195 GLN n 
1 196 ASP n 
1 197 LEU n 
1 198 LEU n 
1 199 ARG n 
1 200 CYS n 
1 201 ARG n 
1 202 VAL n 
1 203 LEU n 
1 204 THR n 
1 205 SER n 
1 206 GLY n 
1 207 ILE n 
1 208 PHE n 
1 209 GLU n 
1 210 THR n 
1 211 LYS n 
1 212 PHE n 
1 213 GLN n 
1 214 VAL n 
1 215 ASP n 
1 216 LYS n 
1 217 VAL n 
1 218 ASN n 
1 219 PHE n 
1 220 HIS n 
1 221 MET n 
1 222 PHE n 
1 223 ASP n 
1 224 VAL n 
1 225 GLY n 
1 226 ALA n 
1 227 GLN n 
1 228 ARG n 
1 229 ASP n 
1 230 GLU n 
1 231 ARG n 
1 232 ARG n 
1 233 LYS n 
1 234 TRP n 
1 235 ILE n 
1 236 GLN n 
1 237 CYS n 
1 238 PHE n 
1 239 ASN n 
1 240 ASP n 
1 241 VAL n 
1 242 THR n 
1 243 ALA n 
1 244 ILE n 
1 245 ILE n 
1 246 PHE n 
1 247 VAL n 
1 248 VAL n 
1 249 ALA n 
1 250 SER n 
1 251 SER n 
1 252 SER n 
1 253 TYR n 
1 254 ASN n 
1 255 MET n 
1 256 VAL n 
1 257 ILE n 
1 258 ARG n 
1 259 GLU n 
1 260 ASP n 
1 261 ASN n 
1 262 GLN n 
1 263 THR n 
1 264 ASN n 
1 265 ARG n 
1 266 LEU n 
1 267 GLN n 
1 268 ALA n 
1 269 ALA n 
1 270 LEU n 
1 271 LYS n 
1 272 LEU n 
1 273 PHE n 
1 274 ASP n 
1 275 SER n 
1 276 ILE n 
1 277 TRP n 
1 278 ASN n 
1 279 ASN n 
1 280 LYS n 
1 281 TRP n 
1 282 LEU n 
1 283 ARG n 
1 284 ASP n 
1 285 THR n 
1 286 SER n 
1 287 VAL n 
1 288 ILE n 
1 289 LEU n 
1 290 PHE n 
1 291 LEU n 
1 292 ASN n 
1 293 LYS n 
1 294 GLN n 
1 295 ASP n 
1 296 LEU n 
1 297 LEU n 
1 298 ALA n 
1 299 GLU n 
1 300 LYS n 
1 301 VAL n 
1 302 LEU n 
1 303 ALA n 
1 304 GLY n 
1 305 LYS n 
1 306 SER n 
1 307 LYS n 
1 308 ILE n 
1 309 GLU n 
1 310 ASP n 
1 311 TYR n 
1 312 PHE n 
1 313 PRO n 
1 314 GLU n 
1 315 PHE n 
1 316 ALA n 
1 317 ARG n 
1 318 TYR n 
1 319 THR n 
1 320 THR n 
1 321 PRO n 
1 322 GLU n 
1 323 ASP n 
1 324 ALA n 
1 325 THR n 
1 326 PRO n 
1 327 GLU n 
1 328 PRO n 
1 329 GLY n 
1 330 GLU n 
1 331 ASP n 
1 332 PRO n 
1 333 ARG n 
1 334 VAL n 
1 335 THR n 
1 336 ARG n 
1 337 ALA n 
1 338 LYS n 
1 339 TYR n 
1 340 PHE n 
1 341 ILE n 
1 342 ARG n 
1 343 ASP n 
1 344 GLU n 
1 345 PHE n 
1 346 LEU n 
1 347 ARG n 
1 348 ILE n 
1 349 SER n 
1 350 THR n 
1 351 ALA n 
1 352 SER n 
1 353 GLY n 
1 354 ASP n 
1 355 GLY n 
1 356 ARG n 
1 357 HIS n 
1 358 TYR n 
1 359 CYS n 
1 360 TYR n 
1 361 PRO n 
1 362 HIS n 
1 363 PHE n 
1 364 THR n 
1 365 CYS n 
1 366 ALA n 
1 367 VAL n 
1 368 ASP n 
1 369 THR n 
1 370 GLU n 
1 371 ASN n 
1 372 ILE n 
1 373 ARG n 
1 374 ARG n 
1 375 VAL n 
1 376 PHE n 
1 377 ASN n 
1 378 ASP n 
1 379 CYS n 
1 380 ARG n 
1 381 ASP n 
1 382 ILE n 
1 383 ILE n 
1 384 GLN n 
1 385 ARG n 
1 386 MET n 
1 387 HIS n 
1 388 LEU n 
1 389 ARG n 
1 390 GLN n 
1 391 TYR n 
1 392 GLU n 
1 393 LEU n 
1 394 LEU n 
2 1   GLN n 
2 2   SER n 
2 3   GLU n 
2 4   LEU n 
2 5   ASP n 
2 6   GLN n 
2 7   LEU n 
2 8   ARG n 
2 9   GLN n 
2 10  GLU n 
2 11  ALA n 
2 12  GLU n 
2 13  GLN n 
2 14  LEU n 
2 15  LYS n 
2 16  ASN n 
2 17  GLN n 
2 18  ILE n 
2 19  ARG n 
2 20  ASP n 
2 21  ALA n 
2 22  ARG n 
2 23  LYS n 
2 24  ALA n 
2 25  CYS n 
2 26  ALA n 
2 27  ASP n 
2 28  ALA n 
2 29  THR n 
2 30  LEU n 
2 31  SER n 
2 32  GLN n 
2 33  ILE n 
2 34  THR n 
2 35  ASN n 
2 36  ASN n 
2 37  ILE n 
2 38  ASP n 
2 39  PRO n 
2 40  VAL n 
2 41  GLY n 
2 42  ARG n 
2 43  ILE n 
2 44  GLN n 
2 45  MET n 
2 46  ARG n 
2 47  THR n 
2 48  ARG n 
2 49  ARG n 
2 50  THR n 
2 51  LEU n 
2 52  ARG n 
2 53  GLY n 
2 54  HIS n 
2 55  LEU n 
2 56  ALA n 
2 57  LYS n 
2 58  ILE n 
2 59  TYR n 
2 60  ALA n 
2 61  MET n 
2 62  HIS n 
2 63  TRP n 
2 64  GLY n 
2 65  THR n 
2 66  ASP n 
2 67  SER n 
2 68  ARG n 
2 69  LEU n 
2 70  LEU n 
2 71  VAL n 
2 72  SER n 
2 73  ALA n 
2 74  SER n 
2 75  GLN n 
2 76  ASP n 
2 77  GLY n 
2 78  LYS n 
2 79  LEU n 
2 80  ILE n 
2 81  ILE n 
2 82  TRP n 
2 83  ASP n 
2 84  SER n 
2 85  TYR n 
2 86  THR n 
2 87  THR n 
2 88  ASN n 
2 89  LYS n 
2 90  VAL n 
2 91  HIS n 
2 92  ALA n 
2 93  ILE n 
2 94  PRO n 
2 95  LEU n 
2 96  ARG n 
2 97  SER n 
2 98  SER n 
2 99  TRP n 
2 100 VAL n 
2 101 MET n 
2 102 THR n 
2 103 CYS n 
2 104 ALA n 
2 105 TYR n 
2 106 ALA n 
2 107 PRO n 
2 108 SER n 
2 109 GLY n 
2 110 ASN n 
2 111 TYR n 
2 112 VAL n 
2 113 ALA n 
2 114 CYS n 
2 115 GLY n 
2 116 GLY n 
2 117 LEU n 
2 118 ASP n 
2 119 ASN n 
2 120 ILE n 
2 121 CYS n 
2 122 SER n 
2 123 ILE n 
2 124 TYR n 
2 125 ASN n 
2 126 LEU n 
2 127 LYS n 
2 128 THR n 
2 129 ARG n 
2 130 GLU n 
2 131 GLY n 
2 132 ASN n 
2 133 VAL n 
2 134 ARG n 
2 135 VAL n 
2 136 SER n 
2 137 ARG n 
2 138 GLU n 
2 139 LEU n 
2 140 ALA n 
2 141 GLY n 
2 142 HIS n 
2 143 THR n 
2 144 GLY n 
2 145 TYR n 
2 146 LEU n 
2 147 SER n 
2 148 CYS n 
2 149 CYS n 
2 150 ARG n 
2 151 PHE n 
2 152 LEU n 
2 153 ASP n 
2 154 ASP n 
2 155 ASN n 
2 156 GLN n 
2 157 ILE n 
2 158 VAL n 
2 159 THR n 
2 160 SER n 
2 161 SER n 
2 162 GLY n 
2 163 ASP n 
2 164 THR n 
2 165 THR n 
2 166 CYS n 
2 167 ALA n 
2 168 LEU n 
2 169 TRP n 
2 170 ASP n 
2 171 ILE n 
2 172 GLU n 
2 173 THR n 
2 174 GLY n 
2 175 GLN n 
2 176 GLN n 
2 177 THR n 
2 178 THR n 
2 179 THR n 
2 180 PHE n 
2 181 THR n 
2 182 GLY n 
2 183 HIS n 
2 184 THR n 
2 185 GLY n 
2 186 ASP n 
2 187 VAL n 
2 188 MET n 
2 189 SER n 
2 190 LEU n 
2 191 SER n 
2 192 LEU n 
2 193 ALA n 
2 194 PRO n 
2 195 ASP n 
2 196 THR n 
2 197 ARG n 
2 198 LEU n 
2 199 PHE n 
2 200 VAL n 
2 201 SER n 
2 202 GLY n 
2 203 ALA n 
2 204 CYS n 
2 205 ASP n 
2 206 ALA n 
2 207 SER n 
2 208 ALA n 
2 209 LYS n 
2 210 LEU n 
2 211 TRP n 
2 212 ASP n 
2 213 VAL n 
2 214 ARG n 
2 215 GLU n 
2 216 GLY n 
2 217 MET n 
2 218 CYS n 
2 219 ARG n 
2 220 GLN n 
2 221 THR n 
2 222 PHE n 
2 223 THR n 
2 224 GLY n 
2 225 HIS n 
2 226 GLU n 
2 227 SER n 
2 228 ASP n 
2 229 ILE n 
2 230 ASN n 
2 231 ALA n 
2 232 ILE n 
2 233 CYS n 
2 234 PHE n 
2 235 PHE n 
2 236 PRO n 
2 237 ASN n 
2 238 GLY n 
2 239 ASN n 
2 240 ALA n 
2 241 PHE n 
2 242 ALA n 
2 243 THR n 
2 244 GLY n 
2 245 SER n 
2 246 ASP n 
2 247 ASP n 
2 248 ALA n 
2 249 THR n 
2 250 CYS n 
2 251 ARG n 
2 252 LEU n 
2 253 PHE n 
2 254 ASP n 
2 255 LEU n 
2 256 ARG n 
2 257 ALA n 
2 258 ASP n 
2 259 GLN n 
2 260 GLU n 
2 261 LEU n 
2 262 MET n 
2 263 THR n 
2 264 TYR n 
2 265 SER n 
2 266 HIS n 
2 267 ASP n 
2 268 ASN n 
2 269 ILE n 
2 270 ILE n 
2 271 CYS n 
2 272 GLY n 
2 273 ILE n 
2 274 THR n 
2 275 SER n 
2 276 VAL n 
2 277 SER n 
2 278 PHE n 
2 279 SER n 
2 280 LYS n 
2 281 SER n 
2 282 GLY n 
2 283 ARG n 
2 284 LEU n 
2 285 LEU n 
2 286 LEU n 
2 287 ALA n 
2 288 GLY n 
2 289 TYR n 
2 290 ASP n 
2 291 ASP n 
2 292 PHE n 
2 293 ASN n 
2 294 CYS n 
2 295 ASN n 
2 296 VAL n 
2 297 TRP n 
2 298 ASP n 
2 299 ALA n 
2 300 LEU n 
2 301 LYS n 
2 302 ALA n 
2 303 ASP n 
2 304 ARG n 
2 305 ALA n 
2 306 GLY n 
2 307 VAL n 
2 308 LEU n 
2 309 ALA n 
2 310 GLY n 
2 311 HIS n 
2 312 ASP n 
2 313 ASN n 
2 314 ARG n 
2 315 VAL n 
2 316 SER n 
2 317 CYS n 
2 318 LEU n 
2 319 GLY n 
2 320 VAL n 
2 321 THR n 
2 322 ASP n 
2 323 ASP n 
2 324 GLY n 
2 325 MET n 
2 326 ALA n 
2 327 VAL n 
2 328 ALA n 
2 329 THR n 
2 330 GLY n 
2 331 SER n 
2 332 TRP n 
2 333 ASP n 
2 334 SER n 
2 335 PHE n 
2 336 LEU n 
2 337 LYS n 
2 338 ILE n 
2 339 TRP n 
2 340 ASN n 
3 1   ASN n 
3 2   THR n 
3 3   ALA n 
3 4   SER n 
3 5   ILE n 
3 6   ALA n 
3 7   GLN n 
3 8   ALA n 
3 9   ARG n 
3 10  LYS n 
3 11  LEU n 
3 12  VAL n 
3 13  GLU n 
3 14  GLN n 
3 15  LEU n 
3 16  LYS n 
3 17  MET n 
3 18  GLU n 
3 19  ALA n 
3 20  ASN n 
3 21  ILE n 
3 22  ASP n 
3 23  ARG n 
3 24  ILE n 
3 25  LYS n 
3 26  VAL n 
3 27  SER n 
3 28  LYS n 
3 29  ALA n 
3 30  ALA n 
3 31  ALA n 
3 32  ASP n 
3 33  LEU n 
3 34  MET n 
3 35  ALA n 
3 36  TYR n 
3 37  CYS n 
3 38  GLU n 
3 39  ALA n 
3 40  HIS n 
3 41  ALA n 
3 42  LYS n 
3 43  GLU n 
3 44  ASP n 
3 45  PRO n 
3 46  LEU n 
3 47  LEU n 
3 48  THR n 
3 49  PRO n 
3 50  VAL n 
3 51  PRO n 
3 52  ALA n 
3 53  SER n 
3 54  GLU n 
3 55  ASN n 
3 56  PRO n 
3 57  PHE n 
3 58  ARG n 
4 1   GLN n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   GLN n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  LEU n 
4 19  ARG n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  ALA n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  THR n 
4 29  PHE n 
4 30  SER n 
4 31  ASN n 
4 32  TYR n 
4 33  LYS n 
4 34  MET n 
4 35  ASN n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLY n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  VAL n 
4 49  SER n 
4 50  ASP n 
4 51  ILE n 
4 52  SER n 
4 53  GLN n 
4 54  SER n 
4 55  GLY n 
4 56  ALA n 
4 57  SER n 
4 58  ILE n 
4 59  SER n 
4 60  TYR n 
4 61  THR n 
4 62  GLY n 
4 63  SER n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  ILE n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASN n 
4 75  ALA n 
4 76  LYS n 
4 77  ASN n 
4 78  THR n 
4 79  LEU n 
4 80  TYR n 
4 81  LEU n 
4 82  GLN n 
4 83  MET n 
4 84  ASN n 
4 85  SER n 
4 86  LEU n 
4 87  LYS n 
4 88  PRO n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  VAL n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  ALA n 
4 98  ARG n 
4 99  CYS n 
4 100 PRO n 
4 101 ALA n 
4 102 PRO n 
4 103 PHE n 
4 104 THR n 
4 105 ARG n 
4 106 ASP n 
4 107 CYS n 
4 108 PHE n 
4 109 ASP n 
4 110 VAL n 
4 111 THR n 
4 112 SER n 
4 113 THR n 
4 114 THR n 
4 115 TYR n 
4 116 ALA n 
4 117 TYR n 
4 118 ARG n 
4 119 GLY n 
4 120 GLN n 
4 121 GLY n 
4 122 THR n 
4 123 GLN n 
4 124 VAL n 
4 125 THR n 
4 126 VAL n 
4 127 SER n 
4 128 SER n 
5 1   HIS n 
5 2   ALA n 
5 3   GLU n 
5 4   GLY n 
5 5   THR n 
5 6   PHE n 
5 7   THR n 
5 8   SER n 
5 9   ASP n 
5 10  VAL n 
5 11  SER n 
5 12  XCP n 
5 13  TYR n 
5 14  LEU n 
5 15  GLU n 
5 16  GLY n 
5 17  GLN n 
5 18  ALA n 
5 19  ALA n 
5 20  LYS n 
5 21  GLU n 
5 22  PHE n 
5 23  ILE n 
5 24  ALA n 
5 25  TRP n 
5 26  LEU n 
5 27  VAL n 
5 28  LYS n 
5 29  GLY n 
5 30  ARG n 
6 1   MET n 
6 2   LYS n 
6 3   THR n 
6 4   ILE n 
6 5   ILE n 
6 6   ALA n 
6 7   LEU n 
6 8   SER n 
6 9   TYR n 
6 10  ILE n 
6 11  PHE n 
6 12  CYS n 
6 13  LEU n 
6 14  VAL n 
6 15  PHE n 
6 16  ALA n 
6 17  ASP n 
6 18  TYR n 
6 19  LYS n 
6 20  ASP n 
6 21  ASP n 
6 22  ASP n 
6 23  ASP n 
6 24  LEU n 
6 25  GLU n 
6 26  VAL n 
6 27  LEU n 
6 28  PHE n 
6 29  GLN n 
6 30  GLY n 
6 31  PRO n 
6 32  ALA n 
6 33  ARG n 
6 34  PRO n 
6 35  GLN n 
6 36  GLY n 
6 37  ALA n 
6 38  THR n 
6 39  VAL n 
6 40  SER n 
6 41  LEU n 
6 42  TRP n 
6 43  GLU n 
6 44  THR n 
6 45  VAL n 
6 46  GLN n 
6 47  LYS n 
6 48  TRP n 
6 49  ARG n 
6 50  GLU n 
6 51  TYR n 
6 52  ARG n 
6 53  ARG n 
6 54  GLN n 
6 55  CYS n 
6 56  GLN n 
6 57  ARG n 
6 58  SER n 
6 59  LEU n 
6 60  THR n 
6 61  GLU n 
6 62  ASP n 
6 63  PRO n 
6 64  PRO n 
6 65  PRO n 
6 66  ALA n 
6 67  THR n 
6 68  ASP n 
6 69  LEU n 
6 70  PHE n 
6 71  CYS n 
6 72  ASN n 
6 73  ARG n 
6 74  THR n 
6 75  PHE n 
6 76  ASP n 
6 77  GLU n 
6 78  TYR n 
6 79  ALA n 
6 80  CYS n 
6 81  TRP n 
6 82  PRO n 
6 83  ASP n 
6 84  GLY n 
6 85  GLU n 
6 86  PRO n 
6 87  GLY n 
6 88  SER n 
6 89  PHE n 
6 90  VAL n 
6 91  ASN n 
6 92  VAL n 
6 93  SER n 
6 94  CYS n 
6 95  PRO n 
6 96  TRP n 
6 97  TYR n 
6 98  LEU n 
6 99  PRO n 
6 100 TRP n 
6 101 ALA n 
6 102 SER n 
6 103 SER n 
6 104 VAL n 
6 105 PRO n 
6 106 GLN n 
6 107 GLY n 
6 108 HIS n 
6 109 VAL n 
6 110 TYR n 
6 111 ARG n 
6 112 PHE n 
6 113 CYS n 
6 114 THR n 
6 115 ALA n 
6 116 GLU n 
6 117 GLY n 
6 118 LEU n 
6 119 TRP n 
6 120 LEU n 
6 121 GLN n 
6 122 LYS n 
6 123 ASP n 
6 124 ASN n 
6 125 SER n 
6 126 SER n 
6 127 LEU n 
6 128 PRO n 
6 129 TRP n 
6 130 ARG n 
6 131 ASP n 
6 132 LEU n 
6 133 SER n 
6 134 GLU n 
6 135 CYS n 
6 136 GLU n 
6 137 GLU n 
6 138 SER n 
6 139 LYS n 
6 140 ARG n 
6 141 GLY n 
6 142 GLU n 
6 143 ARG n 
6 144 SER n 
6 145 SER n 
6 146 PRO n 
6 147 GLU n 
6 148 GLU n 
6 149 GLN n 
6 150 LEU n 
6 151 LEU n 
6 152 PHE n 
6 153 LEU n 
6 154 TYR n 
6 155 ILE n 
6 156 ILE n 
6 157 TYR n 
6 158 THR n 
6 159 VAL n 
6 160 GLY n 
6 161 TYR n 
6 162 ALA n 
6 163 LEU n 
6 164 SER n 
6 165 PHE n 
6 166 SER n 
6 167 ALA n 
6 168 LEU n 
6 169 VAL n 
6 170 ILE n 
6 171 ALA n 
6 172 SER n 
6 173 ALA n 
6 174 ILE n 
6 175 LEU n 
6 176 LEU n 
6 177 GLY n 
6 178 PHE n 
6 179 ARG n 
6 180 HIS n 
6 181 LEU n 
6 182 HIS n 
6 183 CYS n 
6 184 THR n 
6 185 ARG n 
6 186 ASN n 
6 187 TYR n 
6 188 ILE n 
6 189 HIS n 
6 190 LEU n 
6 191 ASN n 
6 192 LEU n 
6 193 PHE n 
6 194 ALA n 
6 195 SER n 
6 196 PHE n 
6 197 ILE n 
6 198 LEU n 
6 199 ARG n 
6 200 ALA n 
6 201 LEU n 
6 202 SER n 
6 203 VAL n 
6 204 PHE n 
6 205 ILE n 
6 206 LYS n 
6 207 ASP n 
6 208 ALA n 
6 209 ALA n 
6 210 LEU n 
6 211 LYS n 
6 212 TRP n 
6 213 MET n 
6 214 TYR n 
6 215 SER n 
6 216 THR n 
6 217 ALA n 
6 218 ALA n 
6 219 GLN n 
6 220 GLN n 
6 221 HIS n 
6 222 GLN n 
6 223 TRP n 
6 224 ASP n 
6 225 GLY n 
6 226 LEU n 
6 227 LEU n 
6 228 SER n 
6 229 TYR n 
6 230 GLN n 
6 231 ASP n 
6 232 SER n 
6 233 LEU n 
6 234 SER n 
6 235 CYS n 
6 236 ARG n 
6 237 LEU n 
6 238 VAL n 
6 239 PHE n 
6 240 LEU n 
6 241 LEU n 
6 242 MET n 
6 243 GLN n 
6 244 TYR n 
6 245 CYS n 
6 246 VAL n 
6 247 ALA n 
6 248 ALA n 
6 249 ASN n 
6 250 TYR n 
6 251 TYR n 
6 252 TRP n 
6 253 LEU n 
6 254 LEU n 
6 255 VAL n 
6 256 GLU n 
6 257 GLY n 
6 258 VAL n 
6 259 TYR n 
6 260 LEU n 
6 261 TYR n 
6 262 THR n 
6 263 LEU n 
6 264 LEU n 
6 265 ALA n 
6 266 PHE n 
6 267 SER n 
6 268 VAL n 
6 269 PHE n 
6 270 SER n 
6 271 GLU n 
6 272 GLN n 
6 273 TRP n 
6 274 ILE n 
6 275 PHE n 
6 276 ARG n 
6 277 LEU n 
6 278 TYR n 
6 279 VAL n 
6 280 SER n 
6 281 ILE n 
6 282 GLY n 
6 283 TRP n 
6 284 GLY n 
6 285 VAL n 
6 286 PRO n 
6 287 LEU n 
6 288 LEU n 
6 289 PHE n 
6 290 VAL n 
6 291 VAL n 
6 292 PRO n 
6 293 TRP n 
6 294 GLY n 
6 295 ILE n 
6 296 VAL n 
6 297 LYS n 
6 298 TYR n 
6 299 LEU n 
6 300 TYR n 
6 301 GLU n 
6 302 ASP n 
6 303 GLU n 
6 304 GLY n 
6 305 CYS n 
6 306 TRP n 
6 307 THR n 
6 308 ARG n 
6 309 ASN n 
6 310 SER n 
6 311 ASN n 
6 312 MET n 
6 313 ASN n 
6 314 TYR n 
6 315 TRP n 
6 316 LEU n 
6 317 ILE n 
6 318 ILE n 
6 319 ARG n 
6 320 LEU n 
6 321 PRO n 
6 322 ILE n 
6 323 LEU n 
6 324 PHE n 
6 325 ALA n 
6 326 ILE n 
6 327 GLY n 
6 328 VAL n 
6 329 ASN n 
6 330 PHE n 
6 331 LEU n 
6 332 ILE n 
6 333 PHE n 
6 334 VAL n 
6 335 ARG n 
6 336 VAL n 
6 337 ILE n 
6 338 CYS n 
6 339 ILE n 
6 340 VAL n 
6 341 VAL n 
6 342 SER n 
6 343 LYS n 
6 344 LEU n 
6 345 LYS n 
6 346 ALA n 
6 347 ASN n 
6 348 LEU n 
6 349 MET n 
6 350 CYS n 
6 351 LYS n 
6 352 THR n 
6 353 ASP n 
6 354 ILE n 
6 355 LYS n 
6 356 CYS n 
6 357 ARG n 
6 358 LEU n 
6 359 ALA n 
6 360 LYS n 
6 361 SER n 
6 362 THR n 
6 363 LEU n 
6 364 THR n 
6 365 LEU n 
6 366 ILE n 
6 367 PRO n 
6 368 LEU n 
6 369 LEU n 
6 370 GLY n 
6 371 THR n 
6 372 HIS n 
6 373 GLU n 
6 374 VAL n 
6 375 ILE n 
6 376 PHE n 
6 377 ALA n 
6 378 PHE n 
6 379 VAL n 
6 380 MET n 
6 381 ASP n 
6 382 GLU n 
6 383 HIS n 
6 384 ALA n 
6 385 ARG n 
6 386 GLY n 
6 387 THR n 
6 388 LEU n 
6 389 ARG n 
6 390 PHE n 
6 391 ILE n 
6 392 LYS n 
6 393 LEU n 
6 394 PHE n 
6 395 THR n 
6 396 GLU n 
6 397 LEU n 
6 398 SER n 
6 399 PHE n 
6 400 THR n 
6 401 SER n 
6 402 PHE n 
6 403 GLN n 
6 404 GLY n 
6 405 LEU n 
6 406 MET n 
6 407 VAL n 
6 408 ALA n 
6 409 ILE n 
6 410 LEU n 
6 411 TYR n 
6 412 CYS n 
6 413 PHE n 
6 414 VAL n 
6 415 ASN n 
6 416 ASN n 
6 417 GLU n 
6 418 VAL n 
6 419 GLN n 
6 420 LEU n 
6 421 GLU n 
6 422 PHE n 
6 423 ARG n 
6 424 LYS n 
6 425 SER n 
6 426 TRP n 
6 427 GLU n 
6 428 ARG n 
6 429 TRP n 
6 430 ARG n 
6 431 LEU n 
6 432 GLU n 
6 433 HIS n 
6 434 LEU n 
6 435 HIS n 
6 436 ILE n 
6 437 GLN n 
6 438 ARG n 
6 439 ASP n 
6 440 SER n 
6 441 SER n 
6 442 MET n 
6 443 LYS n 
6 444 PRO n 
6 445 LEU n 
6 446 LYS n 
6 447 CYS n 
6 448 PRO n 
6 449 THR n 
6 450 SER n 
6 451 SER n 
6 452 LEU n 
6 453 SER n 
6 454 SER n 
6 455 GLY n 
6 456 ALA n 
6 457 THR n 
6 458 ALA n 
6 459 GLY n 
6 460 SER n 
6 461 SER n 
6 462 MET n 
6 463 TYR n 
6 464 THR n 
6 465 ALA n 
6 466 THR n 
6 467 CYS n 
6 468 GLN n 
6 469 ALA n 
6 470 SER n 
6 471 CYS n 
6 472 SER n 
6 473 PRO n 
6 474 ALA n 
6 475 GLY n 
6 476 LEU n 
6 477 GLU n 
6 478 VAL n 
6 479 LEU n 
6 480 PHE n 
6 481 GLN n 
6 482 GLY n 
6 483 PRO n 
6 484 HIS n 
6 485 HIS n 
6 486 HIS n 
6 487 HIS n 
6 488 HIS n 
6 489 HIS n 
6 490 HIS n 
6 491 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 394 human ? 'GNAS, GNAS1, GSP' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni'  7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 340 human ? GNB1               ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni'  7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 58  human ? GNG2               ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni'  7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 128 ?     ? ?                  ? ? ? ? ? ? 'Lama glama'   9844 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
6 1 sample 'Biological sequence' 1 491 human ? GLP1R              ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni'  7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              5 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       30 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                      ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                     ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                   ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                              ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                     ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                    ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                              ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                      ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                    ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                   ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                      ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                       ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                   ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                      ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                       ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                    ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                   ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                     ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                       ? 'C5 H11 N O2'    117.146 
XCP peptide-like        . '(1S,2S)-2-aminocyclopentanecarboxylic acid' ? 'C6 H11 N O2'    129.157 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLY 2   2   ?   ?   ?   A . n 
A 1 3   CYS 3   3   ?   ?   ?   A . n 
A 1 4   LEU 4   4   ?   ?   ?   A . n 
A 1 5   GLY 5   5   ?   ?   ?   A . n 
A 1 6   ASN 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   ?   ?   ?   A . n 
A 1 8   LYS 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  GLU 10  10  ?   ?   ?   A . n 
A 1 11  ASP 11  11  ?   ?   ?   A . n 
A 1 12  GLN 12  12  ?   ?   ?   A . n 
A 1 13  ARG 13  13  ?   ?   ?   A . n 
A 1 14  ASN 14  14  ?   ?   ?   A . n 
A 1 15  GLU 15  15  ?   ?   ?   A . n 
A 1 16  GLU 16  16  16  GLU GLU A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  ALA 18  18  18  ALA ALA A . n 
A 1 19  GLN 19  19  19  GLN GLN A . n 
A 1 20  ARG 20  20  20  ARG ARG A . n 
A 1 21  GLU 21  21  21  GLU GLU A . n 
A 1 22  ALA 22  22  22  ALA ALA A . n 
A 1 23  ASN 23  23  23  ASN ASN A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  LYS 25  25  25  LYS LYS A . n 
A 1 26  ILE 26  26  26  ILE ILE A . n 
A 1 27  GLU 27  27  27  GLU GLU A . n 
A 1 28  LYS 28  28  28  LYS LYS A . n 
A 1 29  GLN 29  29  29  GLN GLN A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  GLN 31  31  31  GLN GLN A . n 
A 1 32  LYS 32  32  32  LYS LYS A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  LYS 34  34  34  LYS LYS A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  ARG 38  38  38  ARG ARG A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  THR 40  40  40  THR THR A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  ARG 42  42  42  ARG ARG A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  GLY 47  47  47  GLY GLY A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  SER 51  51  51  SER SER A . n 
A 1 52  GLY 52  52  52  GLY GLY A . n 
A 1 53  LYS 53  53  53  LYS LYS A . n 
A 1 54  ASN 54  54  54  ASN ASN A . n 
A 1 55  THR 55  55  55  THR THR A . n 
A 1 56  ILE 56  56  56  ILE ILE A . n 
A 1 57  VAL 57  57  57  VAL VAL A . n 
A 1 58  LYS 58  58  58  LYS LYS A . n 
A 1 59  GLN 59  59  59  GLN GLN A . n 
A 1 60  MET 60  60  60  MET MET A . n 
A 1 61  ARG 61  61  61  ARG ARG A . n 
A 1 62  ILE 62  62  ?   ?   ?   A . n 
A 1 63  LEU 63  63  ?   ?   ?   A . n 
A 1 64  HIS 64  64  ?   ?   ?   A . n 
A 1 65  VAL 65  65  ?   ?   ?   A . n 
A 1 66  ASN 66  66  ?   ?   ?   A . n 
A 1 67  GLY 67  67  ?   ?   ?   A . n 
A 1 68  PHE 68  68  ?   ?   ?   A . n 
A 1 69  ASN 69  69  ?   ?   ?   A . n 
A 1 70  GLY 70  70  ?   ?   ?   A . n 
A 1 71  GLU 71  71  ?   ?   ?   A . n 
A 1 72  GLY 72  72  ?   ?   ?   A . n 
A 1 73  GLY 73  73  ?   ?   ?   A . n 
A 1 74  GLU 74  74  ?   ?   ?   A . n 
A 1 75  GLU 75  75  ?   ?   ?   A . n 
A 1 76  ASP 76  76  ?   ?   ?   A . n 
A 1 77  PRO 77  77  ?   ?   ?   A . n 
A 1 78  GLN 78  78  ?   ?   ?   A . n 
A 1 79  ALA 79  79  ?   ?   ?   A . n 
A 1 80  ALA 80  80  ?   ?   ?   A . n 
A 1 81  ARG 81  81  ?   ?   ?   A . n 
A 1 82  SER 82  82  ?   ?   ?   A . n 
A 1 83  ASN 83  83  ?   ?   ?   A . n 
A 1 84  SER 84  84  ?   ?   ?   A . n 
A 1 85  ASP 85  85  ?   ?   ?   A . n 
A 1 86  GLY 86  86  ?   ?   ?   A . n 
A 1 87  GLU 87  87  ?   ?   ?   A . n 
A 1 88  LYS 88  88  ?   ?   ?   A . n 
A 1 89  ALA 89  89  ?   ?   ?   A . n 
A 1 90  THR 90  90  ?   ?   ?   A . n 
A 1 91  LYS 91  91  ?   ?   ?   A . n 
A 1 92  VAL 92  92  ?   ?   ?   A . n 
A 1 93  GLN 93  93  ?   ?   ?   A . n 
A 1 94  ASP 94  94  ?   ?   ?   A . n 
A 1 95  ILE 95  95  ?   ?   ?   A . n 
A 1 96  LYS 96  96  ?   ?   ?   A . n 
A 1 97  ASN 97  97  ?   ?   ?   A . n 
A 1 98  ASN 98  98  ?   ?   ?   A . n 
A 1 99  LEU 99  99  ?   ?   ?   A . n 
A 1 100 LYS 100 100 ?   ?   ?   A . n 
A 1 101 GLU 101 101 ?   ?   ?   A . n 
A 1 102 ALA 102 102 ?   ?   ?   A . n 
A 1 103 ILE 103 103 ?   ?   ?   A . n 
A 1 104 GLU 104 104 ?   ?   ?   A . n 
A 1 105 THR 105 105 ?   ?   ?   A . n 
A 1 106 ILE 106 106 ?   ?   ?   A . n 
A 1 107 VAL 107 107 ?   ?   ?   A . n 
A 1 108 ALA 108 108 ?   ?   ?   A . n 
A 1 109 ALA 109 109 ?   ?   ?   A . n 
A 1 110 MET 110 110 ?   ?   ?   A . n 
A 1 111 SER 111 111 ?   ?   ?   A . n 
A 1 112 ASN 112 112 ?   ?   ?   A . n 
A 1 113 LEU 113 113 ?   ?   ?   A . n 
A 1 114 VAL 114 114 ?   ?   ?   A . n 
A 1 115 PRO 115 115 ?   ?   ?   A . n 
A 1 116 PRO 116 116 ?   ?   ?   A . n 
A 1 117 VAL 117 117 ?   ?   ?   A . n 
A 1 118 GLU 118 118 ?   ?   ?   A . n 
A 1 119 LEU 119 119 ?   ?   ?   A . n 
A 1 120 ALA 120 120 ?   ?   ?   A . n 
A 1 121 ASN 121 121 ?   ?   ?   A . n 
A 1 122 PRO 122 122 ?   ?   ?   A . n 
A 1 123 GLU 123 123 ?   ?   ?   A . n 
A 1 124 ASN 124 124 ?   ?   ?   A . n 
A 1 125 GLN 125 125 ?   ?   ?   A . n 
A 1 126 PHE 126 126 ?   ?   ?   A . n 
A 1 127 ARG 127 127 ?   ?   ?   A . n 
A 1 128 VAL 128 128 ?   ?   ?   A . n 
A 1 129 ASP 129 129 ?   ?   ?   A . n 
A 1 130 TYR 130 130 ?   ?   ?   A . n 
A 1 131 ILE 131 131 ?   ?   ?   A . n 
A 1 132 LEU 132 132 ?   ?   ?   A . n 
A 1 133 SER 133 133 ?   ?   ?   A . n 
A 1 134 VAL 134 134 ?   ?   ?   A . n 
A 1 135 MET 135 135 ?   ?   ?   A . n 
A 1 136 ASN 136 136 ?   ?   ?   A . n 
A 1 137 VAL 137 137 ?   ?   ?   A . n 
A 1 138 PRO 138 138 ?   ?   ?   A . n 
A 1 139 ASP 139 139 ?   ?   ?   A . n 
A 1 140 PHE 140 140 ?   ?   ?   A . n 
A 1 141 ASP 141 141 ?   ?   ?   A . n 
A 1 142 PHE 142 142 ?   ?   ?   A . n 
A 1 143 PRO 143 143 ?   ?   ?   A . n 
A 1 144 PRO 144 144 ?   ?   ?   A . n 
A 1 145 GLU 145 145 ?   ?   ?   A . n 
A 1 146 PHE 146 146 ?   ?   ?   A . n 
A 1 147 TYR 147 147 ?   ?   ?   A . n 
A 1 148 GLU 148 148 ?   ?   ?   A . n 
A 1 149 HIS 149 149 ?   ?   ?   A . n 
A 1 150 ALA 150 150 ?   ?   ?   A . n 
A 1 151 LYS 151 151 ?   ?   ?   A . n 
A 1 152 ALA 152 152 ?   ?   ?   A . n 
A 1 153 LEU 153 153 ?   ?   ?   A . n 
A 1 154 TRP 154 154 ?   ?   ?   A . n 
A 1 155 GLU 155 155 ?   ?   ?   A . n 
A 1 156 ASP 156 156 ?   ?   ?   A . n 
A 1 157 GLU 157 157 ?   ?   ?   A . n 
A 1 158 GLY 158 158 ?   ?   ?   A . n 
A 1 159 VAL 159 159 ?   ?   ?   A . n 
A 1 160 ARG 160 160 ?   ?   ?   A . n 
A 1 161 ALA 161 161 ?   ?   ?   A . n 
A 1 162 CYS 162 162 ?   ?   ?   A . n 
A 1 163 TYR 163 163 ?   ?   ?   A . n 
A 1 164 GLU 164 164 ?   ?   ?   A . n 
A 1 165 ARG 165 165 ?   ?   ?   A . n 
A 1 166 SER 166 166 ?   ?   ?   A . n 
A 1 167 ASN 167 167 ?   ?   ?   A . n 
A 1 168 GLU 168 168 ?   ?   ?   A . n 
A 1 169 TYR 169 169 ?   ?   ?   A . n 
A 1 170 GLN 170 170 ?   ?   ?   A . n 
A 1 171 LEU 171 171 ?   ?   ?   A . n 
A 1 172 ILE 172 172 ?   ?   ?   A . n 
A 1 173 ASP 173 173 ?   ?   ?   A . n 
A 1 174 CYS 174 174 ?   ?   ?   A . n 
A 1 175 ALA 175 175 ?   ?   ?   A . n 
A 1 176 GLN 176 176 ?   ?   ?   A . n 
A 1 177 TYR 177 177 ?   ?   ?   A . n 
A 1 178 PHE 178 178 ?   ?   ?   A . n 
A 1 179 LEU 179 179 ?   ?   ?   A . n 
A 1 180 ASP 180 180 ?   ?   ?   A . n 
A 1 181 LYS 181 181 ?   ?   ?   A . n 
A 1 182 ILE 182 182 ?   ?   ?   A . n 
A 1 183 ASP 183 183 ?   ?   ?   A . n 
A 1 184 VAL 184 184 ?   ?   ?   A . n 
A 1 185 ILE 185 185 ?   ?   ?   A . n 
A 1 186 LYS 186 186 ?   ?   ?   A . n 
A 1 187 GLN 187 187 ?   ?   ?   A . n 
A 1 188 ALA 188 188 ?   ?   ?   A . n 
A 1 189 ASP 189 189 ?   ?   ?   A . n 
A 1 190 TYR 190 190 ?   ?   ?   A . n 
A 1 191 VAL 191 191 ?   ?   ?   A . n 
A 1 192 PRO 192 192 ?   ?   ?   A . n 
A 1 193 SER 193 193 ?   ?   ?   A . n 
A 1 194 ASP 194 194 ?   ?   ?   A . n 
A 1 195 GLN 195 195 ?   ?   ?   A . n 
A 1 196 ASP 196 196 ?   ?   ?   A . n 
A 1 197 LEU 197 197 ?   ?   ?   A . n 
A 1 198 LEU 198 198 ?   ?   ?   A . n 
A 1 199 ARG 199 199 ?   ?   ?   A . n 
A 1 200 CYS 200 200 ?   ?   ?   A . n 
A 1 201 ARG 201 201 ?   ?   ?   A . n 
A 1 202 VAL 202 202 ?   ?   ?   A . n 
A 1 203 LEU 203 203 ?   ?   ?   A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 ILE 207 207 207 ILE ILE A . n 
A 1 208 PHE 208 208 208 PHE PHE A . n 
A 1 209 GLU 209 209 209 GLU GLU A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 LYS 211 211 211 LYS LYS A . n 
A 1 212 PHE 212 212 212 PHE PHE A . n 
A 1 213 GLN 213 213 213 GLN GLN A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 ASP 215 215 215 ASP ASP A . n 
A 1 216 LYS 216 216 216 LYS LYS A . n 
A 1 217 VAL 217 217 217 VAL VAL A . n 
A 1 218 ASN 218 218 218 ASN ASN A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 HIS 220 220 220 HIS HIS A . n 
A 1 221 MET 221 221 221 MET MET A . n 
A 1 222 PHE 222 222 222 PHE PHE A . n 
A 1 223 ASP 223 223 223 ASP ASP A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 GLY 225 225 225 GLY GLY A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 GLU 230 230 230 GLU GLU A . n 
A 1 231 ARG 231 231 231 ARG ARG A . n 
A 1 232 ARG 232 232 232 ARG ARG A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 TRP 234 234 234 TRP TRP A . n 
A 1 235 ILE 235 235 235 ILE ILE A . n 
A 1 236 GLN 236 236 236 GLN GLN A . n 
A 1 237 CYS 237 237 237 CYS CYS A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 ASN 239 239 239 ASN ASN A . n 
A 1 240 ASP 240 240 240 ASP ASP A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 THR 242 242 242 THR THR A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 PHE 246 246 246 PHE PHE A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 VAL 248 248 248 VAL VAL A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 TYR 253 253 253 TYR TYR A . n 
A 1 254 ASN 254 254 254 ASN ASN A . n 
A 1 255 MET 255 255 ?   ?   ?   A . n 
A 1 256 VAL 256 256 ?   ?   ?   A . n 
A 1 257 ILE 257 257 ?   ?   ?   A . n 
A 1 258 ARG 258 258 ?   ?   ?   A . n 
A 1 259 GLU 259 259 ?   ?   ?   A . n 
A 1 260 ASP 260 260 ?   ?   ?   A . n 
A 1 261 ASN 261 261 ?   ?   ?   A . n 
A 1 262 GLN 262 262 262 GLN GLN A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 ASN 264 264 264 ASN ASN A . n 
A 1 265 ARG 265 265 265 ARG ARG A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 GLN 267 267 267 GLN GLN A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 ALA 269 269 269 ALA ALA A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 LYS 271 271 271 LYS LYS A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 PHE 273 273 273 PHE PHE A . n 
A 1 274 ASP 274 274 274 ASP ASP A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 TRP 277 277 277 TRP TRP A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 ASN 279 279 279 ASN ASN A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 TRP 281 281 281 TRP TRP A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 ARG 283 283 283 ARG ARG A . n 
A 1 284 ASP 284 284 284 ASP ASP A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 SER 286 286 286 SER SER A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 PHE 290 290 290 PHE PHE A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 ASN 292 292 292 ASN ASN A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 VAL 301 301 301 VAL VAL A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 GLY 304 304 304 GLY GLY A . n 
A 1 305 LYS 305 305 305 LYS LYS A . n 
A 1 306 SER 306 306 306 SER SER A . n 
A 1 307 LYS 307 307 307 LYS LYS A . n 
A 1 308 ILE 308 308 308 ILE ILE A . n 
A 1 309 GLU 309 309 309 GLU GLU A . n 
A 1 310 ASP 310 310 310 ASP ASP A . n 
A 1 311 TYR 311 311 311 TYR TYR A . n 
A 1 312 PHE 312 312 312 PHE PHE A . n 
A 1 313 PRO 313 313 313 PRO PRO A . n 
A 1 314 GLU 314 314 314 GLU GLU A . n 
A 1 315 PHE 315 315 315 PHE PHE A . n 
A 1 316 ALA 316 316 316 ALA ALA A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 TYR 318 318 318 TYR TYR A . n 
A 1 319 THR 319 319 319 THR THR A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 PRO 321 321 321 PRO PRO A . n 
A 1 322 GLU 322 322 322 GLU GLU A . n 
A 1 323 ASP 323 323 323 ASP ASP A . n 
A 1 324 ALA 324 324 324 ALA ALA A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 PRO 328 328 328 PRO PRO A . n 
A 1 329 GLY 329 329 329 GLY GLY A . n 
A 1 330 GLU 330 330 330 GLU GLU A . n 
A 1 331 ASP 331 331 331 ASP ASP A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 ARG 333 333 333 ARG ARG A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 THR 335 335 335 THR THR A . n 
A 1 336 ARG 336 336 336 ARG ARG A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 LYS 338 338 338 LYS LYS A . n 
A 1 339 TYR 339 339 339 TYR TYR A . n 
A 1 340 PHE 340 340 340 PHE PHE A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 ARG 342 342 342 ARG ARG A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 GLU 344 344 344 GLU GLU A . n 
A 1 345 PHE 345 345 345 PHE PHE A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 ARG 347 347 347 ARG ARG A . n 
A 1 348 ILE 348 348 348 ILE ILE A . n 
A 1 349 SER 349 349 349 SER SER A . n 
A 1 350 THR 350 350 350 THR THR A . n 
A 1 351 ALA 351 351 351 ALA ALA A . n 
A 1 352 SER 352 352 352 SER SER A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 ASP 354 354 354 ASP ASP A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 HIS 357 357 357 HIS HIS A . n 
A 1 358 TYR 358 358 358 TYR TYR A . n 
A 1 359 CYS 359 359 359 CYS CYS A . n 
A 1 360 TYR 360 360 360 TYR TYR A . n 
A 1 361 PRO 361 361 361 PRO PRO A . n 
A 1 362 HIS 362 362 362 HIS HIS A . n 
A 1 363 PHE 363 363 363 PHE PHE A . n 
A 1 364 THR 364 364 364 THR THR A . n 
A 1 365 CYS 365 365 365 CYS CYS A . n 
A 1 366 ALA 366 366 366 ALA ALA A . n 
A 1 367 VAL 367 367 367 VAL VAL A . n 
A 1 368 ASP 368 368 368 ASP ASP A . n 
A 1 369 THR 369 369 369 THR THR A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 ASN 371 371 371 ASN ASN A . n 
A 1 372 ILE 372 372 372 ILE ILE A . n 
A 1 373 ARG 373 373 373 ARG ARG A . n 
A 1 374 ARG 374 374 374 ARG ARG A . n 
A 1 375 VAL 375 375 375 VAL VAL A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 ASN 377 377 377 ASN ASN A . n 
A 1 378 ASP 378 378 378 ASP ASP A . n 
A 1 379 CYS 379 379 379 CYS CYS A . n 
A 1 380 ARG 380 380 380 ARG ARG A . n 
A 1 381 ASP 381 381 381 ASP ASP A . n 
A 1 382 ILE 382 382 382 ILE ILE A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 GLN 384 384 384 GLN GLN A . n 
A 1 385 ARG 385 385 385 ARG ARG A . n 
A 1 386 MET 386 386 386 MET MET A . n 
A 1 387 HIS 387 387 387 HIS HIS A . n 
A 1 388 LEU 388 388 388 LEU LEU A . n 
A 1 389 ARG 389 389 389 ARG ARG A . n 
A 1 390 GLN 390 390 390 GLN GLN A . n 
A 1 391 TYR 391 391 391 TYR TYR A . n 
A 1 392 GLU 392 392 392 GLU GLU A . n 
A 1 393 LEU 393 393 393 LEU LEU A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
B 2 1   GLN 1   1   ?   ?   ?   B . n 
B 2 2   SER 2   2   ?   ?   ?   B . n 
B 2 3   GLU 3   3   ?   ?   ?   B . n 
B 2 4   LEU 4   4   4   LEU LEU B . n 
B 2 5   ASP 5   5   5   ASP ASP B . n 
B 2 6   GLN 6   6   6   GLN GLN B . n 
B 2 7   LEU 7   7   7   LEU LEU B . n 
B 2 8   ARG 8   8   8   ARG ARG B . n 
B 2 9   GLN 9   9   9   GLN GLN B . n 
B 2 10  GLU 10  10  10  GLU GLU B . n 
B 2 11  ALA 11  11  11  ALA ALA B . n 
B 2 12  GLU 12  12  12  GLU GLU B . n 
B 2 13  GLN 13  13  13  GLN GLN B . n 
B 2 14  LEU 14  14  14  LEU LEU B . n 
B 2 15  LYS 15  15  15  LYS LYS B . n 
B 2 16  ASN 16  16  16  ASN ASN B . n 
B 2 17  GLN 17  17  17  GLN GLN B . n 
B 2 18  ILE 18  18  18  ILE ILE B . n 
B 2 19  ARG 19  19  19  ARG ARG B . n 
B 2 20  ASP 20  20  20  ASP ASP B . n 
B 2 21  ALA 21  21  21  ALA ALA B . n 
B 2 22  ARG 22  22  22  ARG ARG B . n 
B 2 23  LYS 23  23  23  LYS LYS B . n 
B 2 24  ALA 24  24  24  ALA ALA B . n 
B 2 25  CYS 25  25  25  CYS CYS B . n 
B 2 26  ALA 26  26  26  ALA ALA B . n 
B 2 27  ASP 27  27  27  ASP ASP B . n 
B 2 28  ALA 28  28  28  ALA ALA B . n 
B 2 29  THR 29  29  29  THR THR B . n 
B 2 30  LEU 30  30  30  LEU LEU B . n 
B 2 31  SER 31  31  31  SER SER B . n 
B 2 32  GLN 32  32  32  GLN GLN B . n 
B 2 33  ILE 33  33  33  ILE ILE B . n 
B 2 34  THR 34  34  34  THR THR B . n 
B 2 35  ASN 35  35  35  ASN ASN B . n 
B 2 36  ASN 36  36  36  ASN ASN B . n 
B 2 37  ILE 37  37  37  ILE ILE B . n 
B 2 38  ASP 38  38  38  ASP ASP B . n 
B 2 39  PRO 39  39  39  PRO PRO B . n 
B 2 40  VAL 40  40  40  VAL VAL B . n 
B 2 41  GLY 41  41  41  GLY GLY B . n 
B 2 42  ARG 42  42  42  ARG ARG B . n 
B 2 43  ILE 43  43  43  ILE ILE B . n 
B 2 44  GLN 44  44  44  GLN GLN B . n 
B 2 45  MET 45  45  45  MET MET B . n 
B 2 46  ARG 46  46  46  ARG ARG B . n 
B 2 47  THR 47  47  47  THR THR B . n 
B 2 48  ARG 48  48  48  ARG ARG B . n 
B 2 49  ARG 49  49  49  ARG ARG B . n 
B 2 50  THR 50  50  50  THR THR B . n 
B 2 51  LEU 51  51  51  LEU LEU B . n 
B 2 52  ARG 52  52  52  ARG ARG B . n 
B 2 53  GLY 53  53  53  GLY GLY B . n 
B 2 54  HIS 54  54  54  HIS HIS B . n 
B 2 55  LEU 55  55  55  LEU LEU B . n 
B 2 56  ALA 56  56  56  ALA ALA B . n 
B 2 57  LYS 57  57  57  LYS LYS B . n 
B 2 58  ILE 58  58  58  ILE ILE B . n 
B 2 59  TYR 59  59  59  TYR TYR B . n 
B 2 60  ALA 60  60  60  ALA ALA B . n 
B 2 61  MET 61  61  61  MET MET B . n 
B 2 62  HIS 62  62  62  HIS HIS B . n 
B 2 63  TRP 63  63  63  TRP TRP B . n 
B 2 64  GLY 64  64  64  GLY GLY B . n 
B 2 65  THR 65  65  65  THR THR B . n 
B 2 66  ASP 66  66  66  ASP ASP B . n 
B 2 67  SER 67  67  67  SER SER B . n 
B 2 68  ARG 68  68  68  ARG ARG B . n 
B 2 69  LEU 69  69  69  LEU LEU B . n 
B 2 70  LEU 70  70  70  LEU LEU B . n 
B 2 71  VAL 71  71  71  VAL VAL B . n 
B 2 72  SER 72  72  72  SER SER B . n 
B 2 73  ALA 73  73  73  ALA ALA B . n 
B 2 74  SER 74  74  74  SER SER B . n 
B 2 75  GLN 75  75  75  GLN GLN B . n 
B 2 76  ASP 76  76  76  ASP ASP B . n 
B 2 77  GLY 77  77  77  GLY GLY B . n 
B 2 78  LYS 78  78  78  LYS LYS B . n 
B 2 79  LEU 79  79  79  LEU LEU B . n 
B 2 80  ILE 80  80  80  ILE ILE B . n 
B 2 81  ILE 81  81  81  ILE ILE B . n 
B 2 82  TRP 82  82  82  TRP TRP B . n 
B 2 83  ASP 83  83  83  ASP ASP B . n 
B 2 84  SER 84  84  84  SER SER B . n 
B 2 85  TYR 85  85  85  TYR TYR B . n 
B 2 86  THR 86  86  86  THR THR B . n 
B 2 87  THR 87  87  87  THR THR B . n 
B 2 88  ASN 88  88  88  ASN ASN B . n 
B 2 89  LYS 89  89  89  LYS LYS B . n 
B 2 90  VAL 90  90  90  VAL VAL B . n 
B 2 91  HIS 91  91  91  HIS HIS B . n 
B 2 92  ALA 92  92  92  ALA ALA B . n 
B 2 93  ILE 93  93  93  ILE ILE B . n 
B 2 94  PRO 94  94  94  PRO PRO B . n 
B 2 95  LEU 95  95  95  LEU LEU B . n 
B 2 96  ARG 96  96  96  ARG ARG B . n 
B 2 97  SER 97  97  97  SER SER B . n 
B 2 98  SER 98  98  98  SER SER B . n 
B 2 99  TRP 99  99  99  TRP TRP B . n 
B 2 100 VAL 100 100 100 VAL VAL B . n 
B 2 101 MET 101 101 101 MET MET B . n 
B 2 102 THR 102 102 102 THR THR B . n 
B 2 103 CYS 103 103 103 CYS CYS B . n 
B 2 104 ALA 104 104 104 ALA ALA B . n 
B 2 105 TYR 105 105 105 TYR TYR B . n 
B 2 106 ALA 106 106 106 ALA ALA B . n 
B 2 107 PRO 107 107 107 PRO PRO B . n 
B 2 108 SER 108 108 108 SER SER B . n 
B 2 109 GLY 109 109 109 GLY GLY B . n 
B 2 110 ASN 110 110 110 ASN ASN B . n 
B 2 111 TYR 111 111 111 TYR TYR B . n 
B 2 112 VAL 112 112 112 VAL VAL B . n 
B 2 113 ALA 113 113 113 ALA ALA B . n 
B 2 114 CYS 114 114 114 CYS CYS B . n 
B 2 115 GLY 115 115 115 GLY GLY B . n 
B 2 116 GLY 116 116 116 GLY GLY B . n 
B 2 117 LEU 117 117 117 LEU LEU B . n 
B 2 118 ASP 118 118 118 ASP ASP B . n 
B 2 119 ASN 119 119 119 ASN ASN B . n 
B 2 120 ILE 120 120 120 ILE ILE B . n 
B 2 121 CYS 121 121 121 CYS CYS B . n 
B 2 122 SER 122 122 122 SER SER B . n 
B 2 123 ILE 123 123 123 ILE ILE B . n 
B 2 124 TYR 124 124 124 TYR TYR B . n 
B 2 125 ASN 125 125 125 ASN ASN B . n 
B 2 126 LEU 126 126 126 LEU LEU B . n 
B 2 127 LYS 127 127 127 LYS LYS B . n 
B 2 128 THR 128 128 128 THR THR B . n 
B 2 129 ARG 129 129 129 ARG ARG B . n 
B 2 130 GLU 130 130 130 GLU GLU B . n 
B 2 131 GLY 131 131 131 GLY GLY B . n 
B 2 132 ASN 132 132 132 ASN ASN B . n 
B 2 133 VAL 133 133 133 VAL VAL B . n 
B 2 134 ARG 134 134 134 ARG ARG B . n 
B 2 135 VAL 135 135 135 VAL VAL B . n 
B 2 136 SER 136 136 136 SER SER B . n 
B 2 137 ARG 137 137 137 ARG ARG B . n 
B 2 138 GLU 138 138 138 GLU GLU B . n 
B 2 139 LEU 139 139 139 LEU LEU B . n 
B 2 140 ALA 140 140 140 ALA ALA B . n 
B 2 141 GLY 141 141 141 GLY GLY B . n 
B 2 142 HIS 142 142 142 HIS HIS B . n 
B 2 143 THR 143 143 143 THR THR B . n 
B 2 144 GLY 144 144 144 GLY GLY B . n 
B 2 145 TYR 145 145 145 TYR TYR B . n 
B 2 146 LEU 146 146 146 LEU LEU B . n 
B 2 147 SER 147 147 147 SER SER B . n 
B 2 148 CYS 148 148 148 CYS CYS B . n 
B 2 149 CYS 149 149 149 CYS CYS B . n 
B 2 150 ARG 150 150 150 ARG ARG B . n 
B 2 151 PHE 151 151 151 PHE PHE B . n 
B 2 152 LEU 152 152 152 LEU LEU B . n 
B 2 153 ASP 153 153 153 ASP ASP B . n 
B 2 154 ASP 154 154 154 ASP ASP B . n 
B 2 155 ASN 155 155 155 ASN ASN B . n 
B 2 156 GLN 156 156 156 GLN GLN B . n 
B 2 157 ILE 157 157 157 ILE ILE B . n 
B 2 158 VAL 158 158 158 VAL VAL B . n 
B 2 159 THR 159 159 159 THR THR B . n 
B 2 160 SER 160 160 160 SER SER B . n 
B 2 161 SER 161 161 161 SER SER B . n 
B 2 162 GLY 162 162 162 GLY GLY B . n 
B 2 163 ASP 163 163 163 ASP ASP B . n 
B 2 164 THR 164 164 164 THR THR B . n 
B 2 165 THR 165 165 165 THR THR B . n 
B 2 166 CYS 166 166 166 CYS CYS B . n 
B 2 167 ALA 167 167 167 ALA ALA B . n 
B 2 168 LEU 168 168 168 LEU LEU B . n 
B 2 169 TRP 169 169 169 TRP TRP B . n 
B 2 170 ASP 170 170 170 ASP ASP B . n 
B 2 171 ILE 171 171 171 ILE ILE B . n 
B 2 172 GLU 172 172 172 GLU GLU B . n 
B 2 173 THR 173 173 173 THR THR B . n 
B 2 174 GLY 174 174 174 GLY GLY B . n 
B 2 175 GLN 175 175 175 GLN GLN B . n 
B 2 176 GLN 176 176 176 GLN GLN B . n 
B 2 177 THR 177 177 177 THR THR B . n 
B 2 178 THR 178 178 178 THR THR B . n 
B 2 179 THR 179 179 179 THR THR B . n 
B 2 180 PHE 180 180 180 PHE PHE B . n 
B 2 181 THR 181 181 181 THR THR B . n 
B 2 182 GLY 182 182 182 GLY GLY B . n 
B 2 183 HIS 183 183 183 HIS HIS B . n 
B 2 184 THR 184 184 184 THR THR B . n 
B 2 185 GLY 185 185 185 GLY GLY B . n 
B 2 186 ASP 186 186 186 ASP ASP B . n 
B 2 187 VAL 187 187 187 VAL VAL B . n 
B 2 188 MET 188 188 188 MET MET B . n 
B 2 189 SER 189 189 189 SER SER B . n 
B 2 190 LEU 190 190 190 LEU LEU B . n 
B 2 191 SER 191 191 191 SER SER B . n 
B 2 192 LEU 192 192 192 LEU LEU B . n 
B 2 193 ALA 193 193 193 ALA ALA B . n 
B 2 194 PRO 194 194 194 PRO PRO B . n 
B 2 195 ASP 195 195 195 ASP ASP B . n 
B 2 196 THR 196 196 196 THR THR B . n 
B 2 197 ARG 197 197 197 ARG ARG B . n 
B 2 198 LEU 198 198 198 LEU LEU B . n 
B 2 199 PHE 199 199 199 PHE PHE B . n 
B 2 200 VAL 200 200 200 VAL VAL B . n 
B 2 201 SER 201 201 201 SER SER B . n 
B 2 202 GLY 202 202 202 GLY GLY B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 CYS 204 204 204 CYS CYS B . n 
B 2 205 ASP 205 205 205 ASP ASP B . n 
B 2 206 ALA 206 206 206 ALA ALA B . n 
B 2 207 SER 207 207 207 SER SER B . n 
B 2 208 ALA 208 208 208 ALA ALA B . n 
B 2 209 LYS 209 209 209 LYS LYS B . n 
B 2 210 LEU 210 210 210 LEU LEU B . n 
B 2 211 TRP 211 211 211 TRP TRP B . n 
B 2 212 ASP 212 212 212 ASP ASP B . n 
B 2 213 VAL 213 213 213 VAL VAL B . n 
B 2 214 ARG 214 214 214 ARG ARG B . n 
B 2 215 GLU 215 215 215 GLU GLU B . n 
B 2 216 GLY 216 216 216 GLY GLY B . n 
B 2 217 MET 217 217 217 MET MET B . n 
B 2 218 CYS 218 218 218 CYS CYS B . n 
B 2 219 ARG 219 219 219 ARG ARG B . n 
B 2 220 GLN 220 220 220 GLN GLN B . n 
B 2 221 THR 221 221 221 THR THR B . n 
B 2 222 PHE 222 222 222 PHE PHE B . n 
B 2 223 THR 223 223 223 THR THR B . n 
B 2 224 GLY 224 224 224 GLY GLY B . n 
B 2 225 HIS 225 225 225 HIS HIS B . n 
B 2 226 GLU 226 226 226 GLU GLU B . n 
B 2 227 SER 227 227 227 SER SER B . n 
B 2 228 ASP 228 228 228 ASP ASP B . n 
B 2 229 ILE 229 229 229 ILE ILE B . n 
B 2 230 ASN 230 230 230 ASN ASN B . n 
B 2 231 ALA 231 231 231 ALA ALA B . n 
B 2 232 ILE 232 232 232 ILE ILE B . n 
B 2 233 CYS 233 233 233 CYS CYS B . n 
B 2 234 PHE 234 234 234 PHE PHE B . n 
B 2 235 PHE 235 235 235 PHE PHE B . n 
B 2 236 PRO 236 236 236 PRO PRO B . n 
B 2 237 ASN 237 237 237 ASN ASN B . n 
B 2 238 GLY 238 238 238 GLY GLY B . n 
B 2 239 ASN 239 239 239 ASN ASN B . n 
B 2 240 ALA 240 240 240 ALA ALA B . n 
B 2 241 PHE 241 241 241 PHE PHE B . n 
B 2 242 ALA 242 242 242 ALA ALA B . n 
B 2 243 THR 243 243 243 THR THR B . n 
B 2 244 GLY 244 244 244 GLY GLY B . n 
B 2 245 SER 245 245 245 SER SER B . n 
B 2 246 ASP 246 246 246 ASP ASP B . n 
B 2 247 ASP 247 247 247 ASP ASP B . n 
B 2 248 ALA 248 248 248 ALA ALA B . n 
B 2 249 THR 249 249 249 THR THR B . n 
B 2 250 CYS 250 250 250 CYS CYS B . n 
B 2 251 ARG 251 251 251 ARG ARG B . n 
B 2 252 LEU 252 252 252 LEU LEU B . n 
B 2 253 PHE 253 253 253 PHE PHE B . n 
B 2 254 ASP 254 254 254 ASP ASP B . n 
B 2 255 LEU 255 255 255 LEU LEU B . n 
B 2 256 ARG 256 256 256 ARG ARG B . n 
B 2 257 ALA 257 257 257 ALA ALA B . n 
B 2 258 ASP 258 258 258 ASP ASP B . n 
B 2 259 GLN 259 259 259 GLN GLN B . n 
B 2 260 GLU 260 260 260 GLU GLU B . n 
B 2 261 LEU 261 261 261 LEU LEU B . n 
B 2 262 MET 262 262 262 MET MET B . n 
B 2 263 THR 263 263 263 THR THR B . n 
B 2 264 TYR 264 264 264 TYR TYR B . n 
B 2 265 SER 265 265 265 SER SER B . n 
B 2 266 HIS 266 266 266 HIS HIS B . n 
B 2 267 ASP 267 267 267 ASP ASP B . n 
B 2 268 ASN 268 268 268 ASN ASN B . n 
B 2 269 ILE 269 269 269 ILE ILE B . n 
B 2 270 ILE 270 270 270 ILE ILE B . n 
B 2 271 CYS 271 271 271 CYS CYS B . n 
B 2 272 GLY 272 272 272 GLY GLY B . n 
B 2 273 ILE 273 273 273 ILE ILE B . n 
B 2 274 THR 274 274 274 THR THR B . n 
B 2 275 SER 275 275 275 SER SER B . n 
B 2 276 VAL 276 276 276 VAL VAL B . n 
B 2 277 SER 277 277 277 SER SER B . n 
B 2 278 PHE 278 278 278 PHE PHE B . n 
B 2 279 SER 279 279 279 SER SER B . n 
B 2 280 LYS 280 280 280 LYS LYS B . n 
B 2 281 SER 281 281 281 SER SER B . n 
B 2 282 GLY 282 282 282 GLY GLY B . n 
B 2 283 ARG 283 283 283 ARG ARG B . n 
B 2 284 LEU 284 284 284 LEU LEU B . n 
B 2 285 LEU 285 285 285 LEU LEU B . n 
B 2 286 LEU 286 286 286 LEU LEU B . n 
B 2 287 ALA 287 287 287 ALA ALA B . n 
B 2 288 GLY 288 288 288 GLY GLY B . n 
B 2 289 TYR 289 289 289 TYR TYR B . n 
B 2 290 ASP 290 290 290 ASP ASP B . n 
B 2 291 ASP 291 291 291 ASP ASP B . n 
B 2 292 PHE 292 292 292 PHE PHE B . n 
B 2 293 ASN 293 293 293 ASN ASN B . n 
B 2 294 CYS 294 294 294 CYS CYS B . n 
B 2 295 ASN 295 295 295 ASN ASN B . n 
B 2 296 VAL 296 296 296 VAL VAL B . n 
B 2 297 TRP 297 297 297 TRP TRP B . n 
B 2 298 ASP 298 298 298 ASP ASP B . n 
B 2 299 ALA 299 299 299 ALA ALA B . n 
B 2 300 LEU 300 300 300 LEU LEU B . n 
B 2 301 LYS 301 301 301 LYS LYS B . n 
B 2 302 ALA 302 302 302 ALA ALA B . n 
B 2 303 ASP 303 303 303 ASP ASP B . n 
B 2 304 ARG 304 304 304 ARG ARG B . n 
B 2 305 ALA 305 305 305 ALA ALA B . n 
B 2 306 GLY 306 306 306 GLY GLY B . n 
B 2 307 VAL 307 307 307 VAL VAL B . n 
B 2 308 LEU 308 308 308 LEU LEU B . n 
B 2 309 ALA 309 309 309 ALA ALA B . n 
B 2 310 GLY 310 310 310 GLY GLY B . n 
B 2 311 HIS 311 311 311 HIS HIS B . n 
B 2 312 ASP 312 312 312 ASP ASP B . n 
B 2 313 ASN 313 313 313 ASN ASN B . n 
B 2 314 ARG 314 314 314 ARG ARG B . n 
B 2 315 VAL 315 315 315 VAL VAL B . n 
B 2 316 SER 316 316 316 SER SER B . n 
B 2 317 CYS 317 317 317 CYS CYS B . n 
B 2 318 LEU 318 318 318 LEU LEU B . n 
B 2 319 GLY 319 319 319 GLY GLY B . n 
B 2 320 VAL 320 320 320 VAL VAL B . n 
B 2 321 THR 321 321 321 THR THR B . n 
B 2 322 ASP 322 322 322 ASP ASP B . n 
B 2 323 ASP 323 323 323 ASP ASP B . n 
B 2 324 GLY 324 324 324 GLY GLY B . n 
B 2 325 MET 325 325 325 MET MET B . n 
B 2 326 ALA 326 326 326 ALA ALA B . n 
B 2 327 VAL 327 327 327 VAL VAL B . n 
B 2 328 ALA 328 328 328 ALA ALA B . n 
B 2 329 THR 329 329 329 THR THR B . n 
B 2 330 GLY 330 330 330 GLY GLY B . n 
B 2 331 SER 331 331 331 SER SER B . n 
B 2 332 TRP 332 332 332 TRP TRP B . n 
B 2 333 ASP 333 333 333 ASP ASP B . n 
B 2 334 SER 334 334 334 SER SER B . n 
B 2 335 PHE 335 335 335 PHE PHE B . n 
B 2 336 LEU 336 336 336 LEU LEU B . n 
B 2 337 LYS 337 337 337 LYS LYS B . n 
B 2 338 ILE 338 338 338 ILE ILE B . n 
B 2 339 TRP 339 339 339 TRP TRP B . n 
B 2 340 ASN 340 340 340 ASN ASN B . n 
C 3 1   ASN 1   5   ?   ?   ?   G . n 
C 3 2   THR 2   6   ?   ?   ?   G . n 
C 3 3   ALA 3   7   ?   ?   ?   G . n 
C 3 4   SER 4   8   8   SER SER G . n 
C 3 5   ILE 5   9   9   ILE ILE G . n 
C 3 6   ALA 6   10  10  ALA ALA G . n 
C 3 7   GLN 7   11  11  GLN GLN G . n 
C 3 8   ALA 8   12  12  ALA ALA G . n 
C 3 9   ARG 9   13  13  ARG ARG G . n 
C 3 10  LYS 10  14  14  LYS LYS G . n 
C 3 11  LEU 11  15  15  LEU LEU G . n 
C 3 12  VAL 12  16  16  VAL VAL G . n 
C 3 13  GLU 13  17  17  GLU GLU G . n 
C 3 14  GLN 14  18  18  GLN GLN G . n 
C 3 15  LEU 15  19  19  LEU LEU G . n 
C 3 16  LYS 16  20  20  LYS LYS G . n 
C 3 17  MET 17  21  21  MET MET G . n 
C 3 18  GLU 18  22  22  GLU GLU G . n 
C 3 19  ALA 19  23  23  ALA ALA G . n 
C 3 20  ASN 20  24  24  ASN ASN G . n 
C 3 21  ILE 21  25  25  ILE ILE G . n 
C 3 22  ASP 22  26  26  ASP ASP G . n 
C 3 23  ARG 23  27  27  ARG ARG G . n 
C 3 24  ILE 24  28  28  ILE ILE G . n 
C 3 25  LYS 25  29  29  LYS LYS G . n 
C 3 26  VAL 26  30  30  VAL VAL G . n 
C 3 27  SER 27  31  31  SER SER G . n 
C 3 28  LYS 28  32  32  LYS LYS G . n 
C 3 29  ALA 29  33  33  ALA ALA G . n 
C 3 30  ALA 30  34  34  ALA ALA G . n 
C 3 31  ALA 31  35  35  ALA ALA G . n 
C 3 32  ASP 32  36  36  ASP ASP G . n 
C 3 33  LEU 33  37  37  LEU LEU G . n 
C 3 34  MET 34  38  38  MET MET G . n 
C 3 35  ALA 35  39  39  ALA ALA G . n 
C 3 36  TYR 36  40  40  TYR TYR G . n 
C 3 37  CYS 37  41  41  CYS CYS G . n 
C 3 38  GLU 38  42  42  GLU GLU G . n 
C 3 39  ALA 39  43  43  ALA ALA G . n 
C 3 40  HIS 40  44  44  HIS HIS G . n 
C 3 41  ALA 41  45  45  ALA ALA G . n 
C 3 42  LYS 42  46  46  LYS LYS G . n 
C 3 43  GLU 43  47  47  GLU GLU G . n 
C 3 44  ASP 44  48  48  ASP ASP G . n 
C 3 45  PRO 45  49  49  PRO PRO G . n 
C 3 46  LEU 46  50  50  LEU LEU G . n 
C 3 47  LEU 47  51  51  LEU LEU G . n 
C 3 48  THR 48  52  52  THR THR G . n 
C 3 49  PRO 49  53  53  PRO PRO G . n 
C 3 50  VAL 50  54  54  VAL VAL G . n 
C 3 51  PRO 51  55  55  PRO PRO G . n 
C 3 52  ALA 52  56  56  ALA ALA G . n 
C 3 53  SER 53  57  57  SER SER G . n 
C 3 54  GLU 54  58  58  GLU GLU G . n 
C 3 55  ASN 55  59  59  ASN ASN G . n 
C 3 56  PRO 56  60  60  PRO PRO G . n 
C 3 57  PHE 57  61  61  PHE PHE G . n 
C 3 58  ARG 58  62  62  ARG ARG G . n 
D 4 1   GLN 1   1   1   GLN GLN N . n 
D 4 2   VAL 2   2   2   VAL VAL N . n 
D 4 3   GLN 3   3   3   GLN GLN N . n 
D 4 4   LEU 4   4   4   LEU LEU N . n 
D 4 5   GLN 5   5   5   GLN GLN N . n 
D 4 6   GLU 6   6   6   GLU GLU N . n 
D 4 7   SER 7   7   7   SER SER N . n 
D 4 8   GLY 8   8   8   GLY GLY N . n 
D 4 9   GLY 9   9   9   GLY GLY N . n 
D 4 10  GLY 10  10  10  GLY GLY N . n 
D 4 11  LEU 11  11  11  LEU LEU N . n 
D 4 12  VAL 12  12  12  VAL VAL N . n 
D 4 13  GLN 13  13  13  GLN GLN N . n 
D 4 14  PRO 14  14  14  PRO PRO N . n 
D 4 15  GLY 15  15  15  GLY GLY N . n 
D 4 16  GLY 16  16  16  GLY GLY N . n 
D 4 17  SER 17  17  17  SER SER N . n 
D 4 18  LEU 18  18  18  LEU LEU N . n 
D 4 19  ARG 19  19  19  ARG ARG N . n 
D 4 20  LEU 20  20  20  LEU LEU N . n 
D 4 21  SER 21  21  21  SER SER N . n 
D 4 22  CYS 22  22  22  CYS CYS N . n 
D 4 23  ALA 23  23  23  ALA ALA N . n 
D 4 24  ALA 24  24  24  ALA ALA N . n 
D 4 25  SER 25  25  25  SER SER N . n 
D 4 26  GLY 26  26  26  GLY GLY N . n 
D 4 27  PHE 27  27  27  PHE PHE N . n 
D 4 28  THR 28  28  28  THR THR N . n 
D 4 29  PHE 29  29  29  PHE PHE N . n 
D 4 30  SER 30  30  30  SER SER N . n 
D 4 31  ASN 31  31  31  ASN ASN N . n 
D 4 32  TYR 32  32  32  TYR TYR N . n 
D 4 33  LYS 33  33  33  LYS LYS N . n 
D 4 34  MET 34  34  34  MET MET N . n 
D 4 35  ASN 35  35  35  ASN ASN N . n 
D 4 36  TRP 36  36  36  TRP TRP N . n 
D 4 37  VAL 37  37  37  VAL VAL N . n 
D 4 38  ARG 38  38  38  ARG ARG N . n 
D 4 39  GLN 39  39  39  GLN GLN N . n 
D 4 40  ALA 40  40  40  ALA ALA N . n 
D 4 41  PRO 41  41  41  PRO PRO N . n 
D 4 42  GLY 42  42  42  GLY GLY N . n 
D 4 43  LYS 43  43  43  LYS LYS N . n 
D 4 44  GLY 44  44  44  GLY GLY N . n 
D 4 45  LEU 45  45  45  LEU LEU N . n 
D 4 46  GLU 46  46  46  GLU GLU N . n 
D 4 47  TRP 47  47  47  TRP TRP N . n 
D 4 48  VAL 48  48  48  VAL VAL N . n 
D 4 49  SER 49  49  49  SER SER N . n 
D 4 50  ASP 50  50  50  ASP ASP N . n 
D 4 51  ILE 51  51  51  ILE ILE N . n 
D 4 52  SER 52  52  52  SER SER N . n 
D 4 53  GLN 53  53  53  GLN GLN N . n 
D 4 54  SER 54  54  54  SER SER N . n 
D 4 55  GLY 55  55  55  GLY GLY N . n 
D 4 56  ALA 56  56  56  ALA ALA N . n 
D 4 57  SER 57  57  57  SER SER N . n 
D 4 58  ILE 58  58  58  ILE ILE N . n 
D 4 59  SER 59  59  59  SER SER N . n 
D 4 60  TYR 60  60  60  TYR TYR N . n 
D 4 61  THR 61  61  61  THR THR N . n 
D 4 62  GLY 62  62  62  GLY GLY N . n 
D 4 63  SER 63  63  63  SER SER N . n 
D 4 64  VAL 64  64  64  VAL VAL N . n 
D 4 65  LYS 65  65  65  LYS LYS N . n 
D 4 66  GLY 66  66  66  GLY GLY N . n 
D 4 67  ARG 67  67  67  ARG ARG N . n 
D 4 68  PHE 68  68  68  PHE PHE N . n 
D 4 69  THR 69  69  69  THR THR N . n 
D 4 70  ILE 70  70  70  ILE ILE N . n 
D 4 71  SER 71  71  71  SER SER N . n 
D 4 72  ARG 72  72  72  ARG ARG N . n 
D 4 73  ASP 73  73  73  ASP ASP N . n 
D 4 74  ASN 74  74  74  ASN ASN N . n 
D 4 75  ALA 75  75  75  ALA ALA N . n 
D 4 76  LYS 76  76  76  LYS LYS N . n 
D 4 77  ASN 77  77  77  ASN ASN N . n 
D 4 78  THR 78  78  78  THR THR N . n 
D 4 79  LEU 79  79  79  LEU LEU N . n 
D 4 80  TYR 80  80  80  TYR TYR N . n 
D 4 81  LEU 81  81  81  LEU LEU N . n 
D 4 82  GLN 82  82  82  GLN GLN N . n 
D 4 83  MET 83  83  83  MET MET N . n 
D 4 84  ASN 84  84  84  ASN ASN N . n 
D 4 85  SER 85  85  85  SER SER N . n 
D 4 86  LEU 86  86  86  LEU LEU N . n 
D 4 87  LYS 87  87  87  LYS LYS N . n 
D 4 88  PRO 88  88  88  PRO PRO N . n 
D 4 89  GLU 89  89  89  GLU GLU N . n 
D 4 90  ASP 90  90  90  ASP ASP N . n 
D 4 91  THR 91  91  91  THR THR N . n 
D 4 92  ALA 92  92  92  ALA ALA N . n 
D 4 93  VAL 93  93  93  VAL VAL N . n 
D 4 94  TYR 94  94  94  TYR TYR N . n 
D 4 95  TYR 95  95  95  TYR TYR N . n 
D 4 96  CYS 96  96  96  CYS CYS N . n 
D 4 97  ALA 97  97  97  ALA ALA N . n 
D 4 98  ARG 98  98  98  ARG ARG N . n 
D 4 99  CYS 99  99  99  CYS CYS N . n 
D 4 100 PRO 100 100 100 PRO PRO N . n 
D 4 101 ALA 101 101 101 ALA ALA N . n 
D 4 102 PRO 102 102 102 PRO PRO N . n 
D 4 103 PHE 103 103 103 PHE PHE N . n 
D 4 104 THR 104 104 104 THR THR N . n 
D 4 105 ARG 105 105 105 ARG ARG N . n 
D 4 106 ASP 106 106 106 ASP ASP N . n 
D 4 107 CYS 107 107 107 CYS CYS N . n 
D 4 108 PHE 108 108 108 PHE PHE N . n 
D 4 109 ASP 109 109 109 ASP ASP N . n 
D 4 110 VAL 110 110 110 VAL VAL N . n 
D 4 111 THR 111 111 111 THR THR N . n 
D 4 112 SER 112 112 112 SER SER N . n 
D 4 113 THR 113 113 113 THR THR N . n 
D 4 114 THR 114 114 114 THR THR N . n 
D 4 115 TYR 115 115 115 TYR TYR N . n 
D 4 116 ALA 116 116 116 ALA ALA N . n 
D 4 117 TYR 117 117 117 TYR TYR N . n 
D 4 118 ARG 118 118 118 ARG ARG N . n 
D 4 119 GLY 119 119 119 GLY GLY N . n 
D 4 120 GLN 120 120 120 GLN GLN N . n 
D 4 121 GLY 121 121 121 GLY GLY N . n 
D 4 122 THR 122 122 122 THR THR N . n 
D 4 123 GLN 123 123 123 GLN GLN N . n 
D 4 124 VAL 124 124 124 VAL VAL N . n 
D 4 125 THR 125 125 125 THR THR N . n 
D 4 126 VAL 126 126 126 VAL VAL N . n 
D 4 127 SER 127 127 ?   ?   ?   N . n 
D 4 128 SER 128 128 ?   ?   ?   N . n 
E 5 1   HIS 1   7   7   HIS HIS P . n 
E 5 2   ALA 2   8   8   ALA ALA P . n 
E 5 3   GLU 3   9   9   GLU GLU P . n 
E 5 4   GLY 4   10  10  GLY GLY P . n 
E 5 5   THR 5   11  11  THR THR P . n 
E 5 6   PHE 6   12  12  PHE PHE P . n 
E 5 7   THR 7   13  13  THR THR P . n 
E 5 8   SER 8   14  14  SER SER P . n 
E 5 9   ASP 9   15  15  ASP ASP P . n 
E 5 10  VAL 10  16  16  VAL VAL P . n 
E 5 11  SER 11  17  17  SER SER P . n 
E 5 12  XCP 12  18  18  XCP XCP P . n 
E 5 13  TYR 13  19  19  TYR TYR P . n 
E 5 14  LEU 14  20  20  LEU LEU P . n 
E 5 15  GLU 15  21  21  GLU GLU P . n 
E 5 16  GLY 16  22  22  GLY GLY P . n 
E 5 17  GLN 17  23  23  GLN GLN P . n 
E 5 18  ALA 18  24  24  ALA ALA P . n 
E 5 19  ALA 19  25  25  ALA ALA P . n 
E 5 20  LYS 20  26  26  LYS LYS P . n 
E 5 21  GLU 21  27  27  GLU GLU P . n 
E 5 22  PHE 22  28  28  PHE PHE P . n 
E 5 23  ILE 23  29  29  ILE ILE P . n 
E 5 24  ALA 24  30  30  ALA ALA P . n 
E 5 25  TRP 25  31  31  TRP TRP P . n 
E 5 26  LEU 26  32  32  LEU LEU P . n 
E 5 27  VAL 27  33  33  VAL VAL P . n 
E 5 28  LYS 28  34  34  LYS LYS P . n 
E 5 29  GLY 29  35  ?   ?   ?   P . n 
E 5 30  ARG 30  36  ?   ?   ?   P . n 
F 6 1   MET 1   -8  ?   ?   ?   R . n 
F 6 2   LYS 2   -7  ?   ?   ?   R . n 
F 6 3   THR 3   -6  ?   ?   ?   R . n 
F 6 4   ILE 4   -5  ?   ?   ?   R . n 
F 6 5   ILE 5   -4  ?   ?   ?   R . n 
F 6 6   ALA 6   -3  ?   ?   ?   R . n 
F 6 7   LEU 7   -2  ?   ?   ?   R . n 
F 6 8   SER 8   -1  ?   ?   ?   R . n 
F 6 9   TYR 9   0   ?   ?   ?   R . n 
F 6 10  ILE 10  1   ?   ?   ?   R . n 
F 6 11  PHE 11  2   ?   ?   ?   R . n 
F 6 12  CYS 12  3   ?   ?   ?   R . n 
F 6 13  LEU 13  4   ?   ?   ?   R . n 
F 6 14  VAL 14  5   ?   ?   ?   R . n 
F 6 15  PHE 15  6   ?   ?   ?   R . n 
F 6 16  ALA 16  7   ?   ?   ?   R . n 
F 6 17  ASP 17  8   ?   ?   ?   R . n 
F 6 18  TYR 18  9   ?   ?   ?   R . n 
F 6 19  LYS 19  10  ?   ?   ?   R . n 
F 6 20  ASP 20  11  ?   ?   ?   R . n 
F 6 21  ASP 21  12  ?   ?   ?   R . n 
F 6 22  ASP 22  13  ?   ?   ?   R . n 
F 6 23  ASP 23  14  ?   ?   ?   R . n 
F 6 24  LEU 24  15  ?   ?   ?   R . n 
F 6 25  GLU 25  16  ?   ?   ?   R . n 
F 6 26  VAL 26  17  ?   ?   ?   R . n 
F 6 27  LEU 27  18  ?   ?   ?   R . n 
F 6 28  PHE 28  19  ?   ?   ?   R . n 
F 6 29  GLN 29  20  ?   ?   ?   R . n 
F 6 30  GLY 30  21  ?   ?   ?   R . n 
F 6 31  PRO 31  22  ?   ?   ?   R . n 
F 6 32  ALA 32  23  ?   ?   ?   R . n 
F 6 33  ARG 33  24  ?   ?   ?   R . n 
F 6 34  PRO 34  25  ?   ?   ?   R . n 
F 6 35  GLN 35  26  ?   ?   ?   R . n 
F 6 36  GLY 36  27  ?   ?   ?   R . n 
F 6 37  ALA 37  28  ?   ?   ?   R . n 
F 6 38  THR 38  29  ?   ?   ?   R . n 
F 6 39  VAL 39  30  30  VAL VAL R . n 
F 6 40  SER 40  31  31  SER SER R . n 
F 6 41  LEU 41  32  32  LEU LEU R . n 
F 6 42  TRP 42  33  33  TRP TRP R . n 
F 6 43  GLU 43  34  34  GLU GLU R . n 
F 6 44  THR 44  35  35  THR THR R . n 
F 6 45  VAL 45  36  36  VAL VAL R . n 
F 6 46  GLN 46  37  37  GLN GLN R . n 
F 6 47  LYS 47  38  38  LYS LYS R . n 
F 6 48  TRP 48  39  39  TRP TRP R . n 
F 6 49  ARG 49  40  40  ARG ARG R . n 
F 6 50  GLU 50  41  41  GLU GLU R . n 
F 6 51  TYR 51  42  42  TYR TYR R . n 
F 6 52  ARG 52  43  43  ARG ARG R . n 
F 6 53  ARG 53  44  44  ARG ARG R . n 
F 6 54  GLN 54  45  45  GLN GLN R . n 
F 6 55  CYS 55  46  46  CYS CYS R . n 
F 6 56  GLN 56  47  47  GLN GLN R . n 
F 6 57  ARG 57  48  48  ARG ARG R . n 
F 6 58  SER 58  49  49  SER SER R . n 
F 6 59  LEU 59  50  50  LEU LEU R . n 
F 6 60  THR 60  51  51  THR THR R . n 
F 6 61  GLU 61  52  52  GLU GLU R . n 
F 6 62  ASP 62  53  53  ASP ASP R . n 
F 6 63  PRO 63  54  54  PRO PRO R . n 
F 6 64  PRO 64  55  55  PRO PRO R . n 
F 6 65  PRO 65  56  56  PRO PRO R . n 
F 6 66  ALA 66  57  57  ALA ALA R . n 
F 6 67  THR 67  58  58  THR THR R . n 
F 6 68  ASP 68  59  59  ASP ASP R . n 
F 6 69  LEU 69  60  60  LEU LEU R . n 
F 6 70  PHE 70  61  61  PHE PHE R . n 
F 6 71  CYS 71  62  62  CYS CYS R . n 
F 6 72  ASN 72  63  63  ASN ASN R . n 
F 6 73  ARG 73  64  64  ARG ARG R . n 
F 6 74  THR 74  65  65  THR THR R . n 
F 6 75  PHE 75  66  66  PHE PHE R . n 
F 6 76  ASP 76  67  67  ASP ASP R . n 
F 6 77  GLU 77  68  68  GLU GLU R . n 
F 6 78  TYR 78  69  69  TYR TYR R . n 
F 6 79  ALA 79  70  70  ALA ALA R . n 
F 6 80  CYS 80  71  71  CYS CYS R . n 
F 6 81  TRP 81  72  72  TRP TRP R . n 
F 6 82  PRO 82  73  73  PRO PRO R . n 
F 6 83  ASP 83  74  74  ASP ASP R . n 
F 6 84  GLY 84  75  75  GLY GLY R . n 
F 6 85  GLU 85  76  76  GLU GLU R . n 
F 6 86  PRO 86  77  77  PRO PRO R . n 
F 6 87  GLY 87  78  78  GLY GLY R . n 
F 6 88  SER 88  79  79  SER SER R . n 
F 6 89  PHE 89  80  80  PHE PHE R . n 
F 6 90  VAL 90  81  81  VAL VAL R . n 
F 6 91  ASN 91  82  82  ASN ASN R . n 
F 6 92  VAL 92  83  83  VAL VAL R . n 
F 6 93  SER 93  84  84  SER SER R . n 
F 6 94  CYS 94  85  85  CYS CYS R . n 
F 6 95  PRO 95  86  86  PRO PRO R . n 
F 6 96  TRP 96  87  87  TRP TRP R . n 
F 6 97  TYR 97  88  88  TYR TYR R . n 
F 6 98  LEU 98  89  89  LEU LEU R . n 
F 6 99  PRO 99  90  90  PRO PRO R . n 
F 6 100 TRP 100 91  91  TRP TRP R . n 
F 6 101 ALA 101 92  92  ALA ALA R . n 
F 6 102 SER 102 93  93  SER SER R . n 
F 6 103 SER 103 94  94  SER SER R . n 
F 6 104 VAL 104 95  95  VAL VAL R . n 
F 6 105 PRO 105 96  96  PRO PRO R . n 
F 6 106 GLN 106 97  97  GLN GLN R . n 
F 6 107 GLY 107 98  98  GLY GLY R . n 
F 6 108 HIS 108 99  99  HIS HIS R . n 
F 6 109 VAL 109 100 100 VAL VAL R . n 
F 6 110 TYR 110 101 101 TYR TYR R . n 
F 6 111 ARG 111 102 102 ARG ARG R . n 
F 6 112 PHE 112 103 103 PHE PHE R . n 
F 6 113 CYS 113 104 104 CYS CYS R . n 
F 6 114 THR 114 105 105 THR THR R . n 
F 6 115 ALA 115 106 106 ALA ALA R . n 
F 6 116 GLU 116 107 107 GLU GLU R . n 
F 6 117 GLY 117 108 108 GLY GLY R . n 
F 6 118 LEU 118 109 109 LEU LEU R . n 
F 6 119 TRP 119 110 110 TRP TRP R . n 
F 6 120 LEU 120 111 111 LEU LEU R . n 
F 6 121 GLN 121 112 112 GLN GLN R . n 
F 6 122 LYS 122 113 113 LYS LYS R . n 
F 6 123 ASP 123 114 114 ASP ASP R . n 
F 6 124 ASN 124 115 115 ASN ASN R . n 
F 6 125 SER 125 116 116 SER SER R . n 
F 6 126 SER 126 117 117 SER SER R . n 
F 6 127 LEU 127 118 118 LEU LEU R . n 
F 6 128 PRO 128 119 119 PRO PRO R . n 
F 6 129 TRP 129 120 120 TRP TRP R . n 
F 6 130 ARG 130 121 121 ARG ARG R . n 
F 6 131 ASP 131 122 122 ASP ASP R . n 
F 6 132 LEU 132 123 123 LEU LEU R . n 
F 6 133 SER 133 124 124 SER SER R . n 
F 6 134 GLU 134 125 125 GLU GLU R . n 
F 6 135 CYS 135 126 126 CYS CYS R . n 
F 6 136 GLU 136 127 127 GLU GLU R . n 
F 6 137 GLU 137 128 128 GLU GLU R . n 
F 6 138 SER 138 129 129 SER SER R . n 
F 6 139 LYS 139 130 ?   ?   ?   R . n 
F 6 140 ARG 140 131 ?   ?   ?   R . n 
F 6 141 GLY 141 132 ?   ?   ?   R . n 
F 6 142 GLU 142 133 ?   ?   ?   R . n 
F 6 143 ARG 143 134 ?   ?   ?   R . n 
F 6 144 SER 144 135 ?   ?   ?   R . n 
F 6 145 SER 145 136 ?   ?   ?   R . n 
F 6 146 PRO 146 137 ?   ?   ?   R . n 
F 6 147 GLU 147 138 138 GLU GLU R . n 
F 6 148 GLU 148 139 139 GLU GLU R . n 
F 6 149 GLN 149 140 140 GLN GLN R . n 
F 6 150 LEU 150 141 141 LEU LEU R . n 
F 6 151 LEU 151 142 142 LEU LEU R . n 
F 6 152 PHE 152 143 143 PHE PHE R . n 
F 6 153 LEU 153 144 144 LEU LEU R . n 
F 6 154 TYR 154 145 145 TYR TYR R . n 
F 6 155 ILE 155 146 146 ILE ILE R . n 
F 6 156 ILE 156 147 147 ILE ILE R . n 
F 6 157 TYR 157 148 148 TYR TYR R . n 
F 6 158 THR 158 149 149 THR THR R . n 
F 6 159 VAL 159 150 150 VAL VAL R . n 
F 6 160 GLY 160 151 151 GLY GLY R . n 
F 6 161 TYR 161 152 152 TYR TYR R . n 
F 6 162 ALA 162 153 153 ALA ALA R . n 
F 6 163 LEU 163 154 154 LEU LEU R . n 
F 6 164 SER 164 155 155 SER SER R . n 
F 6 165 PHE 165 156 156 PHE PHE R . n 
F 6 166 SER 166 157 157 SER SER R . n 
F 6 167 ALA 167 158 158 ALA ALA R . n 
F 6 168 LEU 168 159 159 LEU LEU R . n 
F 6 169 VAL 169 160 160 VAL VAL R . n 
F 6 170 ILE 170 161 161 ILE ILE R . n 
F 6 171 ALA 171 162 162 ALA ALA R . n 
F 6 172 SER 172 163 163 SER SER R . n 
F 6 173 ALA 173 164 164 ALA ALA R . n 
F 6 174 ILE 174 165 165 ILE ILE R . n 
F 6 175 LEU 175 166 166 LEU LEU R . n 
F 6 176 LEU 176 167 167 LEU LEU R . n 
F 6 177 GLY 177 168 168 GLY GLY R . n 
F 6 178 PHE 178 169 169 PHE PHE R . n 
F 6 179 ARG 179 170 170 ARG ARG R . n 
F 6 180 HIS 180 171 171 HIS HIS R . n 
F 6 181 LEU 181 172 172 LEU LEU R . n 
F 6 182 HIS 182 173 173 HIS HIS R . n 
F 6 183 CYS 183 174 174 CYS CYS R . n 
F 6 184 THR 184 175 175 THR THR R . n 
F 6 185 ARG 185 176 176 ARG ARG R . n 
F 6 186 ASN 186 177 177 ASN ASN R . n 
F 6 187 TYR 187 178 178 TYR TYR R . n 
F 6 188 ILE 188 179 179 ILE ILE R . n 
F 6 189 HIS 189 180 180 HIS HIS R . n 
F 6 190 LEU 190 181 181 LEU LEU R . n 
F 6 191 ASN 191 182 182 ASN ASN R . n 
F 6 192 LEU 192 183 183 LEU LEU R . n 
F 6 193 PHE 193 184 184 PHE PHE R . n 
F 6 194 ALA 194 185 185 ALA ALA R . n 
F 6 195 SER 195 186 186 SER SER R . n 
F 6 196 PHE 196 187 187 PHE PHE R . n 
F 6 197 ILE 197 188 188 ILE ILE R . n 
F 6 198 LEU 198 189 189 LEU LEU R . n 
F 6 199 ARG 199 190 190 ARG ARG R . n 
F 6 200 ALA 200 191 191 ALA ALA R . n 
F 6 201 LEU 201 192 192 LEU LEU R . n 
F 6 202 SER 202 193 193 SER SER R . n 
F 6 203 VAL 203 194 194 VAL VAL R . n 
F 6 204 PHE 204 195 195 PHE PHE R . n 
F 6 205 ILE 205 196 196 ILE ILE R . n 
F 6 206 LYS 206 197 197 LYS LYS R . n 
F 6 207 ASP 207 198 198 ASP ASP R . n 
F 6 208 ALA 208 199 199 ALA ALA R . n 
F 6 209 ALA 209 200 200 ALA ALA R . n 
F 6 210 LEU 210 201 201 LEU LEU R . n 
F 6 211 LYS 211 202 202 LYS LYS R . n 
F 6 212 TRP 212 203 203 TRP TRP R . n 
F 6 213 MET 213 204 204 MET MET R . n 
F 6 214 TYR 214 205 205 TYR TYR R . n 
F 6 215 SER 215 206 206 SER SER R . n 
F 6 216 THR 216 207 207 THR THR R . n 
F 6 217 ALA 217 208 208 ALA ALA R . n 
F 6 218 ALA 218 209 209 ALA ALA R . n 
F 6 219 GLN 219 210 210 GLN GLN R . n 
F 6 220 GLN 220 211 211 GLN GLN R . n 
F 6 221 HIS 221 212 212 HIS HIS R . n 
F 6 222 GLN 222 213 213 GLN GLN R . n 
F 6 223 TRP 223 214 214 TRP TRP R . n 
F 6 224 ASP 224 215 215 ASP ASP R . n 
F 6 225 GLY 225 216 ?   ?   ?   R . n 
F 6 226 LEU 226 217 ?   ?   ?   R . n 
F 6 227 LEU 227 218 ?   ?   ?   R . n 
F 6 228 SER 228 219 219 SER SER R . n 
F 6 229 TYR 229 220 220 TYR TYR R . n 
F 6 230 GLN 230 221 221 GLN GLN R . n 
F 6 231 ASP 231 222 222 ASP ASP R . n 
F 6 232 SER 232 223 223 SER SER R . n 
F 6 233 LEU 233 224 224 LEU LEU R . n 
F 6 234 SER 234 225 225 SER SER R . n 
F 6 235 CYS 235 226 226 CYS CYS R . n 
F 6 236 ARG 236 227 227 ARG ARG R . n 
F 6 237 LEU 237 228 228 LEU LEU R . n 
F 6 238 VAL 238 229 229 VAL VAL R . n 
F 6 239 PHE 239 230 230 PHE PHE R . n 
F 6 240 LEU 240 231 231 LEU LEU R . n 
F 6 241 LEU 241 232 232 LEU LEU R . n 
F 6 242 MET 242 233 233 MET MET R . n 
F 6 243 GLN 243 234 234 GLN GLN R . n 
F 6 244 TYR 244 235 235 TYR TYR R . n 
F 6 245 CYS 245 236 236 CYS CYS R . n 
F 6 246 VAL 246 237 237 VAL VAL R . n 
F 6 247 ALA 247 238 238 ALA ALA R . n 
F 6 248 ALA 248 239 239 ALA ALA R . n 
F 6 249 ASN 249 240 240 ASN ASN R . n 
F 6 250 TYR 250 241 241 TYR TYR R . n 
F 6 251 TYR 251 242 242 TYR TYR R . n 
F 6 252 TRP 252 243 243 TRP TRP R . n 
F 6 253 LEU 253 244 244 LEU LEU R . n 
F 6 254 LEU 254 245 245 LEU LEU R . n 
F 6 255 VAL 255 246 246 VAL VAL R . n 
F 6 256 GLU 256 247 247 GLU GLU R . n 
F 6 257 GLY 257 248 248 GLY GLY R . n 
F 6 258 VAL 258 249 249 VAL VAL R . n 
F 6 259 TYR 259 250 250 TYR TYR R . n 
F 6 260 LEU 260 251 251 LEU LEU R . n 
F 6 261 TYR 261 252 252 TYR TYR R . n 
F 6 262 THR 262 253 253 THR THR R . n 
F 6 263 LEU 263 254 254 LEU LEU R . n 
F 6 264 LEU 264 255 255 LEU LEU R . n 
F 6 265 ALA 265 256 256 ALA ALA R . n 
F 6 266 PHE 266 257 257 PHE PHE R . n 
F 6 267 SER 267 258 258 SER SER R . n 
F 6 268 VAL 268 259 259 VAL VAL R . n 
F 6 269 PHE 269 260 260 PHE PHE R . n 
F 6 270 SER 270 261 261 SER SER R . n 
F 6 271 GLU 271 262 262 GLU GLU R . n 
F 6 272 GLN 272 263 263 GLN GLN R . n 
F 6 273 TRP 273 264 264 TRP TRP R . n 
F 6 274 ILE 274 265 265 ILE ILE R . n 
F 6 275 PHE 275 266 266 PHE PHE R . n 
F 6 276 ARG 276 267 267 ARG ARG R . n 
F 6 277 LEU 277 268 268 LEU LEU R . n 
F 6 278 TYR 278 269 269 TYR TYR R . n 
F 6 279 VAL 279 270 270 VAL VAL R . n 
F 6 280 SER 280 271 271 SER SER R . n 
F 6 281 ILE 281 272 272 ILE ILE R . n 
F 6 282 GLY 282 273 273 GLY GLY R . n 
F 6 283 TRP 283 274 274 TRP TRP R . n 
F 6 284 GLY 284 275 275 GLY GLY R . n 
F 6 285 VAL 285 276 276 VAL VAL R . n 
F 6 286 PRO 286 277 277 PRO PRO R . n 
F 6 287 LEU 287 278 278 LEU LEU R . n 
F 6 288 LEU 288 279 279 LEU LEU R . n 
F 6 289 PHE 289 280 280 PHE PHE R . n 
F 6 290 VAL 290 281 281 VAL VAL R . n 
F 6 291 VAL 291 282 282 VAL VAL R . n 
F 6 292 PRO 292 283 283 PRO PRO R . n 
F 6 293 TRP 293 284 284 TRP TRP R . n 
F 6 294 GLY 294 285 285 GLY GLY R . n 
F 6 295 ILE 295 286 286 ILE ILE R . n 
F 6 296 VAL 296 287 287 VAL VAL R . n 
F 6 297 LYS 297 288 288 LYS LYS R . n 
F 6 298 TYR 298 289 289 TYR TYR R . n 
F 6 299 LEU 299 290 290 LEU LEU R . n 
F 6 300 TYR 300 291 291 TYR TYR R . n 
F 6 301 GLU 301 292 292 GLU GLU R . n 
F 6 302 ASP 302 293 293 ASP ASP R . n 
F 6 303 GLU 303 294 294 GLU GLU R . n 
F 6 304 GLY 304 295 295 GLY GLY R . n 
F 6 305 CYS 305 296 296 CYS CYS R . n 
F 6 306 TRP 306 297 297 TRP TRP R . n 
F 6 307 THR 307 298 298 THR THR R . n 
F 6 308 ARG 308 299 299 ARG ARG R . n 
F 6 309 ASN 309 300 300 ASN ASN R . n 
F 6 310 SER 310 301 301 SER SER R . n 
F 6 311 ASN 311 302 302 ASN ASN R . n 
F 6 312 MET 312 303 303 MET MET R . n 
F 6 313 ASN 313 304 304 ASN ASN R . n 
F 6 314 TYR 314 305 305 TYR TYR R . n 
F 6 315 TRP 315 306 306 TRP TRP R . n 
F 6 316 LEU 316 307 307 LEU LEU R . n 
F 6 317 ILE 317 308 308 ILE ILE R . n 
F 6 318 ILE 318 309 309 ILE ILE R . n 
F 6 319 ARG 319 310 310 ARG ARG R . n 
F 6 320 LEU 320 311 311 LEU LEU R . n 
F 6 321 PRO 321 312 312 PRO PRO R . n 
F 6 322 ILE 322 313 313 ILE ILE R . n 
F 6 323 LEU 323 314 314 LEU LEU R . n 
F 6 324 PHE 324 315 315 PHE PHE R . n 
F 6 325 ALA 325 316 316 ALA ALA R . n 
F 6 326 ILE 326 317 317 ILE ILE R . n 
F 6 327 GLY 327 318 318 GLY GLY R . n 
F 6 328 VAL 328 319 319 VAL VAL R . n 
F 6 329 ASN 329 320 320 ASN ASN R . n 
F 6 330 PHE 330 321 321 PHE PHE R . n 
F 6 331 LEU 331 322 322 LEU LEU R . n 
F 6 332 ILE 332 323 323 ILE ILE R . n 
F 6 333 PHE 333 324 324 PHE PHE R . n 
F 6 334 VAL 334 325 325 VAL VAL R . n 
F 6 335 ARG 335 326 326 ARG ARG R . n 
F 6 336 VAL 336 327 327 VAL VAL R . n 
F 6 337 ILE 337 328 328 ILE ILE R . n 
F 6 338 CYS 338 329 329 CYS CYS R . n 
F 6 339 ILE 339 330 330 ILE ILE R . n 
F 6 340 VAL 340 331 331 VAL VAL R . n 
F 6 341 VAL 341 332 332 VAL VAL R . n 
F 6 342 SER 342 333 333 SER SER R . n 
F 6 343 LYS 343 334 334 LYS LYS R . n 
F 6 344 LEU 344 335 335 LEU LEU R . n 
F 6 345 LYS 345 336 336 LYS LYS R . n 
F 6 346 ALA 346 337 337 ALA ALA R . n 
F 6 347 ASN 347 338 338 ASN ASN R . n 
F 6 348 LEU 348 339 ?   ?   ?   R . n 
F 6 349 MET 349 340 ?   ?   ?   R . n 
F 6 350 CYS 350 341 ?   ?   ?   R . n 
F 6 351 LYS 351 342 ?   ?   ?   R . n 
F 6 352 THR 352 343 ?   ?   ?   R . n 
F 6 353 ASP 353 344 344 ASP ASP R . n 
F 6 354 ILE 354 345 345 ILE ILE R . n 
F 6 355 LYS 355 346 346 LYS LYS R . n 
F 6 356 CYS 356 347 347 CYS CYS R . n 
F 6 357 ARG 357 348 348 ARG ARG R . n 
F 6 358 LEU 358 349 349 LEU LEU R . n 
F 6 359 ALA 359 350 350 ALA ALA R . n 
F 6 360 LYS 360 351 351 LYS LYS R . n 
F 6 361 SER 361 352 352 SER SER R . n 
F 6 362 THR 362 353 353 THR THR R . n 
F 6 363 LEU 363 354 354 LEU LEU R . n 
F 6 364 THR 364 355 355 THR THR R . n 
F 6 365 LEU 365 356 356 LEU LEU R . n 
F 6 366 ILE 366 357 357 ILE ILE R . n 
F 6 367 PRO 367 358 358 PRO PRO R . n 
F 6 368 LEU 368 359 359 LEU LEU R . n 
F 6 369 LEU 369 360 360 LEU LEU R . n 
F 6 370 GLY 370 361 361 GLY GLY R . n 
F 6 371 THR 371 362 362 THR THR R . n 
F 6 372 HIS 372 363 363 HIS HIS R . n 
F 6 373 GLU 373 364 364 GLU GLU R . n 
F 6 374 VAL 374 365 365 VAL VAL R . n 
F 6 375 ILE 375 366 366 ILE ILE R . n 
F 6 376 PHE 376 367 367 PHE PHE R . n 
F 6 377 ALA 377 368 368 ALA ALA R . n 
F 6 378 PHE 378 369 369 PHE PHE R . n 
F 6 379 VAL 379 370 370 VAL VAL R . n 
F 6 380 MET 380 371 371 MET MET R . n 
F 6 381 ASP 381 372 372 ASP ASP R . n 
F 6 382 GLU 382 373 373 GLU GLU R . n 
F 6 383 HIS 383 374 374 HIS HIS R . n 
F 6 384 ALA 384 375 375 ALA ALA R . n 
F 6 385 ARG 385 376 376 ARG ARG R . n 
F 6 386 GLY 386 377 377 GLY GLY R . n 
F 6 387 THR 387 378 378 THR THR R . n 
F 6 388 LEU 388 379 379 LEU LEU R . n 
F 6 389 ARG 389 380 380 ARG ARG R . n 
F 6 390 PHE 390 381 381 PHE PHE R . n 
F 6 391 ILE 391 382 382 ILE ILE R . n 
F 6 392 LYS 392 383 383 LYS LYS R . n 
F 6 393 LEU 393 384 384 LEU LEU R . n 
F 6 394 PHE 394 385 385 PHE PHE R . n 
F 6 395 THR 395 386 386 THR THR R . n 
F 6 396 GLU 396 387 387 GLU GLU R . n 
F 6 397 LEU 397 388 388 LEU LEU R . n 
F 6 398 SER 398 389 389 SER SER R . n 
F 6 399 PHE 399 390 390 PHE PHE R . n 
F 6 400 THR 400 391 391 THR THR R . n 
F 6 401 SER 401 392 392 SER SER R . n 
F 6 402 PHE 402 393 393 PHE PHE R . n 
F 6 403 GLN 403 394 394 GLN GLN R . n 
F 6 404 GLY 404 395 395 GLY GLY R . n 
F 6 405 LEU 405 396 396 LEU LEU R . n 
F 6 406 MET 406 397 397 MET MET R . n 
F 6 407 VAL 407 398 398 VAL VAL R . n 
F 6 408 ALA 408 399 399 ALA ALA R . n 
F 6 409 ILE 409 400 400 ILE ILE R . n 
F 6 410 LEU 410 401 401 LEU LEU R . n 
F 6 411 TYR 411 402 402 TYR TYR R . n 
F 6 412 CYS 412 403 403 CYS CYS R . n 
F 6 413 PHE 413 404 404 PHE PHE R . n 
F 6 414 VAL 414 405 405 VAL VAL R . n 
F 6 415 ASN 415 406 406 ASN ASN R . n 
F 6 416 ASN 416 407 407 ASN ASN R . n 
F 6 417 GLU 417 408 408 GLU GLU R . n 
F 6 418 VAL 418 409 409 VAL VAL R . n 
F 6 419 GLN 419 410 410 GLN GLN R . n 
F 6 420 LEU 420 411 411 LEU LEU R . n 
F 6 421 GLU 421 412 412 GLU GLU R . n 
F 6 422 PHE 422 413 413 PHE PHE R . n 
F 6 423 ARG 423 414 414 ARG ARG R . n 
F 6 424 LYS 424 415 415 LYS LYS R . n 
F 6 425 SER 425 416 416 SER SER R . n 
F 6 426 TRP 426 417 417 TRP TRP R . n 
F 6 427 GLU 427 418 418 GLU GLU R . n 
F 6 428 ARG 428 419 419 ARG ARG R . n 
F 6 429 TRP 429 420 420 TRP TRP R . n 
F 6 430 ARG 430 421 421 ARG ARG R . n 
F 6 431 LEU 431 422 422 LEU LEU R . n 
F 6 432 GLU 432 423 423 GLU GLU R . n 
F 6 433 HIS 433 424 ?   ?   ?   R . n 
F 6 434 LEU 434 425 ?   ?   ?   R . n 
F 6 435 HIS 435 426 ?   ?   ?   R . n 
F 6 436 ILE 436 427 ?   ?   ?   R . n 
F 6 437 GLN 437 428 ?   ?   ?   R . n 
F 6 438 ARG 438 429 ?   ?   ?   R . n 
F 6 439 ASP 439 430 ?   ?   ?   R . n 
F 6 440 SER 440 431 ?   ?   ?   R . n 
F 6 441 SER 441 432 ?   ?   ?   R . n 
F 6 442 MET 442 433 ?   ?   ?   R . n 
F 6 443 LYS 443 434 ?   ?   ?   R . n 
F 6 444 PRO 444 435 ?   ?   ?   R . n 
F 6 445 LEU 445 436 ?   ?   ?   R . n 
F 6 446 LYS 446 437 ?   ?   ?   R . n 
F 6 447 CYS 447 438 ?   ?   ?   R . n 
F 6 448 PRO 448 439 ?   ?   ?   R . n 
F 6 449 THR 449 440 ?   ?   ?   R . n 
F 6 450 SER 450 441 ?   ?   ?   R . n 
F 6 451 SER 451 442 ?   ?   ?   R . n 
F 6 452 LEU 452 443 ?   ?   ?   R . n 
F 6 453 SER 453 444 ?   ?   ?   R . n 
F 6 454 SER 454 445 ?   ?   ?   R . n 
F 6 455 GLY 455 446 ?   ?   ?   R . n 
F 6 456 ALA 456 447 ?   ?   ?   R . n 
F 6 457 THR 457 448 ?   ?   ?   R . n 
F 6 458 ALA 458 449 ?   ?   ?   R . n 
F 6 459 GLY 459 450 ?   ?   ?   R . n 
F 6 460 SER 460 451 ?   ?   ?   R . n 
F 6 461 SER 461 452 ?   ?   ?   R . n 
F 6 462 MET 462 453 ?   ?   ?   R . n 
F 6 463 TYR 463 454 ?   ?   ?   R . n 
F 6 464 THR 464 455 ?   ?   ?   R . n 
F 6 465 ALA 465 456 ?   ?   ?   R . n 
F 6 466 THR 466 457 ?   ?   ?   R . n 
F 6 467 CYS 467 458 ?   ?   ?   R . n 
F 6 468 GLN 468 459 ?   ?   ?   R . n 
F 6 469 ALA 469 460 ?   ?   ?   R . n 
F 6 470 SER 470 461 ?   ?   ?   R . n 
F 6 471 CYS 471 462 ?   ?   ?   R . n 
F 6 472 SER 472 463 ?   ?   ?   R . n 
F 6 473 PRO 473 464 ?   ?   ?   R . n 
F 6 474 ALA 474 465 ?   ?   ?   R . n 
F 6 475 GLY 475 466 ?   ?   ?   R . n 
F 6 476 LEU 476 467 ?   ?   ?   R . n 
F 6 477 GLU 477 468 ?   ?   ?   R . n 
F 6 478 VAL 478 469 ?   ?   ?   R . n 
F 6 479 LEU 479 470 ?   ?   ?   R . n 
F 6 480 PHE 480 471 ?   ?   ?   R . n 
F 6 481 GLN 481 472 ?   ?   ?   R . n 
F 6 482 GLY 482 473 ?   ?   ?   R . n 
F 6 483 PRO 483 474 ?   ?   ?   R . n 
F 6 484 HIS 484 475 ?   ?   ?   R . n 
F 6 485 HIS 485 476 ?   ?   ?   R . n 
F 6 486 HIS 486 477 ?   ?   ?   R . n 
F 6 487 HIS 487 478 ?   ?   ?   R . n 
F 6 488 HIS 488 479 ?   ?   ?   R . n 
F 6 489 HIS 489 480 ?   ?   ?   R . n 
F 6 490 HIS 490 481 ?   ?   ?   R . n 
F 6 491 HIS 491 482 ?   ?   ?   R . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XCP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XCP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A LYS 17  ? CG  ? A LYS 17  CG  
2   1 Y 1 A LYS 17  ? CD  ? A LYS 17  CD  
3   1 Y 1 A LYS 17  ? CE  ? A LYS 17  CE  
4   1 Y 1 A LYS 17  ? NZ  ? A LYS 17  NZ  
5   1 Y 1 A ARG 20  ? CG  ? A ARG 20  CG  
6   1 Y 1 A ARG 20  ? CD  ? A ARG 20  CD  
7   1 Y 1 A ARG 20  ? NE  ? A ARG 20  NE  
8   1 Y 1 A ARG 20  ? CZ  ? A ARG 20  CZ  
9   1 Y 1 A ARG 20  ? NH1 ? A ARG 20  NH1 
10  1 Y 1 A ARG 20  ? NH2 ? A ARG 20  NH2 
11  1 Y 1 A GLU 21  ? CG  ? A GLU 21  CG  
12  1 Y 1 A GLU 21  ? CD  ? A GLU 21  CD  
13  1 Y 1 A GLU 21  ? OE1 ? A GLU 21  OE1 
14  1 Y 1 A GLU 21  ? OE2 ? A GLU 21  OE2 
15  1 Y 1 A LYS 24  ? CG  ? A LYS 24  CG  
16  1 Y 1 A LYS 24  ? CD  ? A LYS 24  CD  
17  1 Y 1 A LYS 24  ? CE  ? A LYS 24  CE  
18  1 Y 1 A LYS 24  ? NZ  ? A LYS 24  NZ  
19  1 Y 1 A GLU 50  ? CG  ? A GLU 50  CG  
20  1 Y 1 A GLU 50  ? CD  ? A GLU 50  CD  
21  1 Y 1 A GLU 50  ? OE1 ? A GLU 50  OE1 
22  1 Y 1 A GLU 50  ? OE2 ? A GLU 50  OE2 
23  1 Y 1 A LYS 216 ? CG  ? A LYS 216 CG  
24  1 Y 1 A LYS 216 ? CD  ? A LYS 216 CD  
25  1 Y 1 A LYS 216 ? CE  ? A LYS 216 CE  
26  1 Y 1 A LYS 216 ? NZ  ? A LYS 216 NZ  
27  1 Y 1 A GLN 262 ? CG  ? A GLN 262 CG  
28  1 Y 1 A GLN 262 ? CD  ? A GLN 262 CD  
29  1 Y 1 A GLN 262 ? OE1 ? A GLN 262 OE1 
30  1 Y 1 A GLN 262 ? NE2 ? A GLN 262 NE2 
31  1 Y 1 A THR 263 ? OG1 ? A THR 263 OG1 
32  1 Y 1 A THR 263 ? CG2 ? A THR 263 CG2 
33  1 Y 1 A ARG 265 ? CG  ? A ARG 265 CG  
34  1 Y 1 A ARG 265 ? CD  ? A ARG 265 CD  
35  1 Y 1 A ARG 265 ? NE  ? A ARG 265 NE  
36  1 Y 1 A ARG 265 ? CZ  ? A ARG 265 CZ  
37  1 Y 1 A ARG 265 ? NH1 ? A ARG 265 NH1 
38  1 Y 1 A ARG 265 ? NH2 ? A ARG 265 NH2 
39  1 Y 1 A GLU 299 ? CG  ? A GLU 299 CG  
40  1 Y 1 A GLU 299 ? CD  ? A GLU 299 CD  
41  1 Y 1 A GLU 299 ? OE1 ? A GLU 299 OE1 
42  1 Y 1 A GLU 299 ? OE2 ? A GLU 299 OE2 
43  1 Y 1 A LYS 305 ? CG  ? A LYS 305 CG  
44  1 Y 1 A LYS 305 ? CD  ? A LYS 305 CD  
45  1 Y 1 A LYS 305 ? CE  ? A LYS 305 CE  
46  1 Y 1 A LYS 305 ? NZ  ? A LYS 305 NZ  
47  1 Y 1 A SER 306 ? OG  ? A SER 306 OG  
48  1 Y 1 A ARG 317 ? CG  ? A ARG 317 CG  
49  1 Y 1 A ARG 317 ? CD  ? A ARG 317 CD  
50  1 Y 1 A ARG 317 ? NE  ? A ARG 317 NE  
51  1 Y 1 A ARG 317 ? CZ  ? A ARG 317 CZ  
52  1 Y 1 A ARG 317 ? NH1 ? A ARG 317 NH1 
53  1 Y 1 A ARG 317 ? NH2 ? A ARG 317 NH2 
54  1 Y 1 A GLU 322 ? CG  ? A GLU 322 CG  
55  1 Y 1 A GLU 322 ? CD  ? A GLU 322 CD  
56  1 Y 1 A GLU 322 ? OE1 ? A GLU 322 OE1 
57  1 Y 1 A GLU 322 ? OE2 ? A GLU 322 OE2 
58  1 Y 1 A THR 325 ? OG1 ? A THR 325 OG1 
59  1 Y 1 A THR 325 ? CG2 ? A THR 325 CG2 
60  1 Y 1 A GLU 327 ? CG  ? A GLU 327 CG  
61  1 Y 1 A GLU 327 ? CD  ? A GLU 327 CD  
62  1 Y 1 A GLU 327 ? OE1 ? A GLU 327 OE1 
63  1 Y 1 A GLU 327 ? OE2 ? A GLU 327 OE2 
64  1 Y 1 A GLU 330 ? CG  ? A GLU 330 CG  
65  1 Y 1 A GLU 330 ? CD  ? A GLU 330 CD  
66  1 Y 1 A GLU 330 ? OE1 ? A GLU 330 OE1 
67  1 Y 1 A GLU 330 ? OE2 ? A GLU 330 OE2 
68  1 Y 1 B ASP 5   ? CG  ? B ASP 5   CG  
69  1 Y 1 B ASP 5   ? OD1 ? B ASP 5   OD1 
70  1 Y 1 B ASP 5   ? OD2 ? B ASP 5   OD2 
71  1 Y 1 B GLN 6   ? CG  ? B GLN 6   CG  
72  1 Y 1 B GLN 6   ? CD  ? B GLN 6   CD  
73  1 Y 1 B GLN 6   ? OE1 ? B GLN 6   OE1 
74  1 Y 1 B GLN 6   ? NE2 ? B GLN 6   NE2 
75  1 Y 1 B GLU 10  ? CG  ? B GLU 10  CG  
76  1 Y 1 B GLU 10  ? CD  ? B GLU 10  CD  
77  1 Y 1 B GLU 10  ? OE1 ? B GLU 10  OE1 
78  1 Y 1 B GLU 10  ? OE2 ? B GLU 10  OE2 
79  1 Y 1 B LYS 15  ? CG  ? B LYS 15  CG  
80  1 Y 1 B LYS 15  ? CD  ? B LYS 15  CD  
81  1 Y 1 B LYS 15  ? CE  ? B LYS 15  CE  
82  1 Y 1 B LYS 15  ? NZ  ? B LYS 15  NZ  
83  1 Y 1 B ARG 129 ? CG  ? B ARG 129 CG  
84  1 Y 1 B ARG 129 ? CD  ? B ARG 129 CD  
85  1 Y 1 B ARG 129 ? NE  ? B ARG 129 NE  
86  1 Y 1 B ARG 129 ? CZ  ? B ARG 129 CZ  
87  1 Y 1 B ARG 129 ? NH1 ? B ARG 129 NH1 
88  1 Y 1 B ARG 129 ? NH2 ? B ARG 129 NH2 
89  1 Y 1 B GLU 130 ? CG  ? B GLU 130 CG  
90  1 Y 1 B GLU 130 ? CD  ? B GLU 130 CD  
91  1 Y 1 B GLU 130 ? OE1 ? B GLU 130 OE1 
92  1 Y 1 B GLU 130 ? OE2 ? B GLU 130 OE2 
93  1 Y 1 B ARG 134 ? CG  ? B ARG 134 CG  
94  1 Y 1 B ARG 134 ? CD  ? B ARG 134 CD  
95  1 Y 1 B ARG 134 ? NE  ? B ARG 134 NE  
96  1 Y 1 B ARG 134 ? CZ  ? B ARG 134 CZ  
97  1 Y 1 B ARG 134 ? NH1 ? B ARG 134 NH1 
98  1 Y 1 B ARG 134 ? NH2 ? B ARG 134 NH2 
99  1 Y 1 B GLU 172 ? CG  ? B GLU 172 CG  
100 1 Y 1 B GLU 172 ? CD  ? B GLU 172 CD  
101 1 Y 1 B GLU 172 ? OE1 ? B GLU 172 OE1 
102 1 Y 1 B GLU 172 ? OE2 ? B GLU 172 OE2 
103 1 Y 1 B ARG 214 ? CG  ? B ARG 214 CG  
104 1 Y 1 B ARG 214 ? CD  ? B ARG 214 CD  
105 1 Y 1 B ARG 214 ? NE  ? B ARG 214 NE  
106 1 Y 1 B ARG 214 ? CZ  ? B ARG 214 CZ  
107 1 Y 1 B ARG 214 ? NH1 ? B ARG 214 NH1 
108 1 Y 1 B ARG 214 ? NH2 ? B ARG 214 NH2 
109 1 Y 1 G LYS 20  ? CG  ? C LYS 16  CG  
110 1 Y 1 G LYS 20  ? CD  ? C LYS 16  CD  
111 1 Y 1 G LYS 20  ? CE  ? C LYS 16  CE  
112 1 Y 1 G LYS 20  ? NZ  ? C LYS 16  NZ  
113 1 Y 1 G VAL 54  ? CG1 ? C VAL 50  CG1 
114 1 Y 1 G VAL 54  ? CG2 ? C VAL 50  CG2 
115 1 Y 1 G SER 57  ? OG  ? C SER 53  OG  
116 1 Y 1 G GLU 58  ? CG  ? C GLU 54  CG  
117 1 Y 1 G GLU 58  ? CD  ? C GLU 54  CD  
118 1 Y 1 G GLU 58  ? OE1 ? C GLU 54  OE1 
119 1 Y 1 G GLU 58  ? OE2 ? C GLU 54  OE2 
120 1 Y 1 G ARG 62  ? CG  ? C ARG 58  CG  
121 1 Y 1 G ARG 62  ? CD  ? C ARG 58  CD  
122 1 Y 1 G ARG 62  ? NE  ? C ARG 58  NE  
123 1 Y 1 G ARG 62  ? CZ  ? C ARG 58  CZ  
124 1 Y 1 G ARG 62  ? NH1 ? C ARG 58  NH1 
125 1 Y 1 G ARG 62  ? NH2 ? C ARG 58  NH2 
126 1 Y 1 N LYS 43  ? CG  ? D LYS 43  CG  
127 1 Y 1 N LYS 43  ? CD  ? D LYS 43  CD  
128 1 Y 1 N LYS 43  ? CE  ? D LYS 43  CE  
129 1 Y 1 N LYS 43  ? NZ  ? D LYS 43  NZ  
130 1 Y 1 N LYS 76  ? CG  ? D LYS 76  CG  
131 1 Y 1 N LYS 76  ? CD  ? D LYS 76  CD  
132 1 Y 1 N LYS 76  ? CE  ? D LYS 76  CE  
133 1 Y 1 N LYS 76  ? NZ  ? D LYS 76  NZ  
134 1 Y 1 N LYS 87  ? CG  ? D LYS 87  CG  
135 1 Y 1 N LYS 87  ? CD  ? D LYS 87  CD  
136 1 Y 1 N LYS 87  ? CE  ? D LYS 87  CE  
137 1 Y 1 N LYS 87  ? NZ  ? D LYS 87  NZ  
138 1 Y 1 P VAL 33  ? CG1 ? E VAL 27  CG1 
139 1 Y 1 P VAL 33  ? CG2 ? E VAL 27  CG2 
140 1 Y 1 P LYS 34  ? CG  ? E LYS 28  CG  
141 1 Y 1 P LYS 34  ? CD  ? E LYS 28  CD  
142 1 Y 1 P LYS 34  ? CE  ? E LYS 28  CE  
143 1 Y 1 P LYS 34  ? NZ  ? E LYS 28  NZ  
144 1 Y 1 R SER 31  ? OG  ? F SER 40  OG  
145 1 Y 1 R GLU 34  ? CG  ? F GLU 43  CG  
146 1 Y 1 R GLU 34  ? CD  ? F GLU 43  CD  
147 1 Y 1 R GLU 34  ? OE1 ? F GLU 43  OE1 
148 1 Y 1 R GLU 34  ? OE2 ? F GLU 43  OE2 
149 1 Y 1 R THR 35  ? OG1 ? F THR 44  OG1 
150 1 Y 1 R THR 35  ? CG2 ? F THR 44  CG2 
151 1 Y 1 R GLN 37  ? CG  ? F GLN 46  CG  
152 1 Y 1 R GLN 37  ? CD  ? F GLN 46  CD  
153 1 Y 1 R GLN 37  ? OE1 ? F GLN 46  OE1 
154 1 Y 1 R GLN 37  ? NE2 ? F GLN 46  NE2 
155 1 Y 1 R ARG 40  ? CG  ? F ARG 49  CG  
156 1 Y 1 R ARG 40  ? CD  ? F ARG 49  CD  
157 1 Y 1 R ARG 40  ? NE  ? F ARG 49  NE  
158 1 Y 1 R ARG 40  ? CZ  ? F ARG 49  CZ  
159 1 Y 1 R ARG 40  ? NH1 ? F ARG 49  NH1 
160 1 Y 1 R ARG 40  ? NH2 ? F ARG 49  NH2 
161 1 Y 1 R GLU 41  ? CG  ? F GLU 50  CG  
162 1 Y 1 R GLU 41  ? CD  ? F GLU 50  CD  
163 1 Y 1 R GLU 41  ? OE1 ? F GLU 50  OE1 
164 1 Y 1 R GLU 41  ? OE2 ? F GLU 50  OE2 
165 1 Y 1 R TYR 42  ? CG  ? F TYR 51  CG  
166 1 Y 1 R TYR 42  ? CD1 ? F TYR 51  CD1 
167 1 Y 1 R TYR 42  ? CD2 ? F TYR 51  CD2 
168 1 Y 1 R TYR 42  ? CE1 ? F TYR 51  CE1 
169 1 Y 1 R TYR 42  ? CE2 ? F TYR 51  CE2 
170 1 Y 1 R TYR 42  ? CZ  ? F TYR 51  CZ  
171 1 Y 1 R TYR 42  ? OH  ? F TYR 51  OH  
172 1 Y 1 R ARG 44  ? CG  ? F ARG 53  CG  
173 1 Y 1 R ARG 44  ? CD  ? F ARG 53  CD  
174 1 Y 1 R ARG 44  ? NE  ? F ARG 53  NE  
175 1 Y 1 R ARG 44  ? CZ  ? F ARG 53  CZ  
176 1 Y 1 R ARG 44  ? NH1 ? F ARG 53  NH1 
177 1 Y 1 R ARG 44  ? NH2 ? F ARG 53  NH2 
178 1 Y 1 R GLN 45  ? CG  ? F GLN 54  CG  
179 1 Y 1 R GLN 45  ? CD  ? F GLN 54  CD  
180 1 Y 1 R GLN 45  ? OE1 ? F GLN 54  OE1 
181 1 Y 1 R GLN 45  ? NE2 ? F GLN 54  NE2 
182 1 Y 1 R GLN 47  ? CG  ? F GLN 56  CG  
183 1 Y 1 R GLN 47  ? CD  ? F GLN 56  CD  
184 1 Y 1 R GLN 47  ? OE1 ? F GLN 56  OE1 
185 1 Y 1 R GLN 47  ? NE2 ? F GLN 56  NE2 
186 1 Y 1 R ARG 48  ? CG  ? F ARG 57  CG  
187 1 Y 1 R ARG 48  ? CD  ? F ARG 57  CD  
188 1 Y 1 R ARG 48  ? NE  ? F ARG 57  NE  
189 1 Y 1 R ARG 48  ? CZ  ? F ARG 57  CZ  
190 1 Y 1 R ARG 48  ? NH1 ? F ARG 57  NH1 
191 1 Y 1 R ARG 48  ? NH2 ? F ARG 57  NH2 
192 1 Y 1 R SER 49  ? OG  ? F SER 58  OG  
193 1 Y 1 R LEU 50  ? CG  ? F LEU 59  CG  
194 1 Y 1 R LEU 50  ? CD1 ? F LEU 59  CD1 
195 1 Y 1 R LEU 50  ? CD2 ? F LEU 59  CD2 
196 1 Y 1 R THR 51  ? OG1 ? F THR 60  OG1 
197 1 Y 1 R THR 51  ? CG2 ? F THR 60  CG2 
198 1 Y 1 R GLU 52  ? CG  ? F GLU 61  CG  
199 1 Y 1 R GLU 52  ? CD  ? F GLU 61  CD  
200 1 Y 1 R GLU 52  ? OE1 ? F GLU 61  OE1 
201 1 Y 1 R GLU 52  ? OE2 ? F GLU 61  OE2 
202 1 Y 1 R ASP 53  ? CG  ? F ASP 62  CG  
203 1 Y 1 R ASP 53  ? OD1 ? F ASP 62  OD1 
204 1 Y 1 R ASP 53  ? OD2 ? F ASP 62  OD2 
205 1 Y 1 R THR 58  ? OG1 ? F THR 67  OG1 
206 1 Y 1 R THR 58  ? CG2 ? F THR 67  CG2 
207 1 Y 1 R ASP 59  ? CG  ? F ASP 68  CG  
208 1 Y 1 R ASP 59  ? OD1 ? F ASP 68  OD1 
209 1 Y 1 R ASP 59  ? OD2 ? F ASP 68  OD2 
210 1 Y 1 R LEU 60  ? CG  ? F LEU 69  CG  
211 1 Y 1 R LEU 60  ? CD1 ? F LEU 69  CD1 
212 1 Y 1 R LEU 60  ? CD2 ? F LEU 69  CD2 
213 1 Y 1 R PHE 61  ? CG  ? F PHE 70  CG  
214 1 Y 1 R PHE 61  ? CD1 ? F PHE 70  CD1 
215 1 Y 1 R PHE 61  ? CD2 ? F PHE 70  CD2 
216 1 Y 1 R PHE 61  ? CE1 ? F PHE 70  CE1 
217 1 Y 1 R PHE 61  ? CE2 ? F PHE 70  CE2 
218 1 Y 1 R PHE 61  ? CZ  ? F PHE 70  CZ  
219 1 Y 1 R ARG 64  ? CG  ? F ARG 73  CG  
220 1 Y 1 R ARG 64  ? CD  ? F ARG 73  CD  
221 1 Y 1 R ARG 64  ? NE  ? F ARG 73  NE  
222 1 Y 1 R ARG 64  ? CZ  ? F ARG 73  CZ  
223 1 Y 1 R ARG 64  ? NH1 ? F ARG 73  NH1 
224 1 Y 1 R ARG 64  ? NH2 ? F ARG 73  NH2 
225 1 Y 1 R THR 65  ? OG1 ? F THR 74  OG1 
226 1 Y 1 R THR 65  ? CG2 ? F THR 74  CG2 
227 1 Y 1 R PHE 66  ? CG  ? F PHE 75  CG  
228 1 Y 1 R PHE 66  ? CD1 ? F PHE 75  CD1 
229 1 Y 1 R PHE 66  ? CD2 ? F PHE 75  CD2 
230 1 Y 1 R PHE 66  ? CE1 ? F PHE 75  CE1 
231 1 Y 1 R PHE 66  ? CE2 ? F PHE 75  CE2 
232 1 Y 1 R PHE 66  ? CZ  ? F PHE 75  CZ  
233 1 Y 1 R ASP 67  ? CG  ? F ASP 76  CG  
234 1 Y 1 R ASP 67  ? OD1 ? F ASP 76  OD1 
235 1 Y 1 R ASP 67  ? OD2 ? F ASP 76  OD2 
236 1 Y 1 R GLU 68  ? CG  ? F GLU 77  CG  
237 1 Y 1 R GLU 68  ? CD  ? F GLU 77  CD  
238 1 Y 1 R GLU 68  ? OE1 ? F GLU 77  OE1 
239 1 Y 1 R GLU 68  ? OE2 ? F GLU 77  OE2 
240 1 Y 1 R ASP 74  ? CG  ? F ASP 83  CG  
241 1 Y 1 R ASP 74  ? OD1 ? F ASP 83  OD1 
242 1 Y 1 R ASP 74  ? OD2 ? F ASP 83  OD2 
243 1 Y 1 R GLU 76  ? CG  ? F GLU 85  CG  
244 1 Y 1 R GLU 76  ? CD  ? F GLU 85  CD  
245 1 Y 1 R GLU 76  ? OE1 ? F GLU 85  OE1 
246 1 Y 1 R GLU 76  ? OE2 ? F GLU 85  OE2 
247 1 Y 1 R SER 79  ? OG  ? F SER 88  OG  
248 1 Y 1 R PHE 80  ? CG  ? F PHE 89  CG  
249 1 Y 1 R PHE 80  ? CD1 ? F PHE 89  CD1 
250 1 Y 1 R PHE 80  ? CD2 ? F PHE 89  CD2 
251 1 Y 1 R PHE 80  ? CE1 ? F PHE 89  CE1 
252 1 Y 1 R PHE 80  ? CE2 ? F PHE 89  CE2 
253 1 Y 1 R PHE 80  ? CZ  ? F PHE 89  CZ  
254 1 Y 1 R VAL 81  ? CG1 ? F VAL 90  CG1 
255 1 Y 1 R VAL 81  ? CG2 ? F VAL 90  CG2 
256 1 Y 1 R ASN 82  ? CG  ? F ASN 91  CG  
257 1 Y 1 R ASN 82  ? OD1 ? F ASN 91  OD1 
258 1 Y 1 R ASN 82  ? ND2 ? F ASN 91  ND2 
259 1 Y 1 R VAL 83  ? CG1 ? F VAL 92  CG1 
260 1 Y 1 R VAL 83  ? CG2 ? F VAL 92  CG2 
261 1 Y 1 R SER 84  ? OG  ? F SER 93  OG  
262 1 Y 1 R TYR 88  ? CG  ? F TYR 97  CG  
263 1 Y 1 R TYR 88  ? CD1 ? F TYR 97  CD1 
264 1 Y 1 R TYR 88  ? CD2 ? F TYR 97  CD2 
265 1 Y 1 R TYR 88  ? CE1 ? F TYR 97  CE1 
266 1 Y 1 R TYR 88  ? CE2 ? F TYR 97  CE2 
267 1 Y 1 R TYR 88  ? CZ  ? F TYR 97  CZ  
268 1 Y 1 R TYR 88  ? OH  ? F TYR 97  OH  
269 1 Y 1 R PRO 90  ? CG  ? F PRO 99  CG  
270 1 Y 1 R PRO 90  ? CD  ? F PRO 99  CD  
271 1 Y 1 R SER 93  ? OG  ? F SER 102 OG  
272 1 Y 1 R SER 94  ? OG  ? F SER 103 OG  
273 1 Y 1 R VAL 95  ? CG1 ? F VAL 104 CG1 
274 1 Y 1 R VAL 95  ? CG2 ? F VAL 104 CG2 
275 1 Y 1 R GLN 97  ? CG  ? F GLN 106 CG  
276 1 Y 1 R GLN 97  ? CD  ? F GLN 106 CD  
277 1 Y 1 R GLN 97  ? OE1 ? F GLN 106 OE1 
278 1 Y 1 R GLN 97  ? NE2 ? F GLN 106 NE2 
279 1 Y 1 R HIS 99  ? CG  ? F HIS 108 CG  
280 1 Y 1 R HIS 99  ? ND1 ? F HIS 108 ND1 
281 1 Y 1 R HIS 99  ? CD2 ? F HIS 108 CD2 
282 1 Y 1 R HIS 99  ? CE1 ? F HIS 108 CE1 
283 1 Y 1 R HIS 99  ? NE2 ? F HIS 108 NE2 
284 1 Y 1 R VAL 100 ? CG1 ? F VAL 109 CG1 
285 1 Y 1 R VAL 100 ? CG2 ? F VAL 109 CG2 
286 1 Y 1 R TYR 101 ? CG  ? F TYR 110 CG  
287 1 Y 1 R TYR 101 ? CD1 ? F TYR 110 CD1 
288 1 Y 1 R TYR 101 ? CD2 ? F TYR 110 CD2 
289 1 Y 1 R TYR 101 ? CE1 ? F TYR 110 CE1 
290 1 Y 1 R TYR 101 ? CE2 ? F TYR 110 CE2 
291 1 Y 1 R TYR 101 ? CZ  ? F TYR 110 CZ  
292 1 Y 1 R TYR 101 ? OH  ? F TYR 110 OH  
293 1 Y 1 R ARG 102 ? CG  ? F ARG 111 CG  
294 1 Y 1 R ARG 102 ? CD  ? F ARG 111 CD  
295 1 Y 1 R ARG 102 ? NE  ? F ARG 111 NE  
296 1 Y 1 R ARG 102 ? CZ  ? F ARG 111 CZ  
297 1 Y 1 R ARG 102 ? NH1 ? F ARG 111 NH1 
298 1 Y 1 R ARG 102 ? NH2 ? F ARG 111 NH2 
299 1 Y 1 R PHE 103 ? CG  ? F PHE 112 CG  
300 1 Y 1 R PHE 103 ? CD1 ? F PHE 112 CD1 
301 1 Y 1 R PHE 103 ? CD2 ? F PHE 112 CD2 
302 1 Y 1 R PHE 103 ? CE1 ? F PHE 112 CE1 
303 1 Y 1 R PHE 103 ? CE2 ? F PHE 112 CE2 
304 1 Y 1 R PHE 103 ? CZ  ? F PHE 112 CZ  
305 1 Y 1 R THR 105 ? OG1 ? F THR 114 OG1 
306 1 Y 1 R THR 105 ? CG2 ? F THR 114 CG2 
307 1 Y 1 R GLU 107 ? CG  ? F GLU 116 CG  
308 1 Y 1 R GLU 107 ? CD  ? F GLU 116 CD  
309 1 Y 1 R GLU 107 ? OE1 ? F GLU 116 OE1 
310 1 Y 1 R GLU 107 ? OE2 ? F GLU 116 OE2 
311 1 Y 1 R LEU 109 ? CG  ? F LEU 118 CG  
312 1 Y 1 R LEU 109 ? CD1 ? F LEU 118 CD1 
313 1 Y 1 R LEU 109 ? CD2 ? F LEU 118 CD2 
314 1 Y 1 R TRP 110 ? CG  ? F TRP 119 CG  
315 1 Y 1 R TRP 110 ? CD1 ? F TRP 119 CD1 
316 1 Y 1 R TRP 110 ? CD2 ? F TRP 119 CD2 
317 1 Y 1 R TRP 110 ? NE1 ? F TRP 119 NE1 
318 1 Y 1 R TRP 110 ? CE2 ? F TRP 119 CE2 
319 1 Y 1 R TRP 110 ? CE3 ? F TRP 119 CE3 
320 1 Y 1 R TRP 110 ? CZ2 ? F TRP 119 CZ2 
321 1 Y 1 R TRP 110 ? CZ3 ? F TRP 119 CZ3 
322 1 Y 1 R TRP 110 ? CH2 ? F TRP 119 CH2 
323 1 Y 1 R LEU 111 ? CG  ? F LEU 120 CG  
324 1 Y 1 R LEU 111 ? CD1 ? F LEU 120 CD1 
325 1 Y 1 R LEU 111 ? CD2 ? F LEU 120 CD2 
326 1 Y 1 R GLN 112 ? CG  ? F GLN 121 CG  
327 1 Y 1 R GLN 112 ? CD  ? F GLN 121 CD  
328 1 Y 1 R GLN 112 ? OE1 ? F GLN 121 OE1 
329 1 Y 1 R GLN 112 ? NE2 ? F GLN 121 NE2 
330 1 Y 1 R LYS 113 ? CG  ? F LYS 122 CG  
331 1 Y 1 R LYS 113 ? CD  ? F LYS 122 CD  
332 1 Y 1 R LYS 113 ? CE  ? F LYS 122 CE  
333 1 Y 1 R LYS 113 ? NZ  ? F LYS 122 NZ  
334 1 Y 1 R ASP 114 ? CG  ? F ASP 123 CG  
335 1 Y 1 R ASP 114 ? OD1 ? F ASP 123 OD1 
336 1 Y 1 R ASP 114 ? OD2 ? F ASP 123 OD2 
337 1 Y 1 R ASN 115 ? CG  ? F ASN 124 CG  
338 1 Y 1 R ASN 115 ? OD1 ? F ASN 124 OD1 
339 1 Y 1 R ASN 115 ? ND2 ? F ASN 124 ND2 
340 1 Y 1 R SER 116 ? OG  ? F SER 125 OG  
341 1 Y 1 R SER 117 ? OG  ? F SER 126 OG  
342 1 Y 1 R LEU 118 ? CG  ? F LEU 127 CG  
343 1 Y 1 R LEU 118 ? CD1 ? F LEU 127 CD1 
344 1 Y 1 R LEU 118 ? CD2 ? F LEU 127 CD2 
345 1 Y 1 R PRO 119 ? CG  ? F PRO 128 CG  
346 1 Y 1 R PRO 119 ? CD  ? F PRO 128 CD  
347 1 Y 1 R ASP 122 ? CG  ? F ASP 131 CG  
348 1 Y 1 R ASP 122 ? OD1 ? F ASP 131 OD1 
349 1 Y 1 R ASP 122 ? OD2 ? F ASP 131 OD2 
350 1 Y 1 R LEU 123 ? CG  ? F LEU 132 CG  
351 1 Y 1 R LEU 123 ? CD1 ? F LEU 132 CD1 
352 1 Y 1 R LEU 123 ? CD2 ? F LEU 132 CD2 
353 1 Y 1 R SER 124 ? OG  ? F SER 133 OG  
354 1 Y 1 R GLU 125 ? CG  ? F GLU 134 CG  
355 1 Y 1 R GLU 125 ? CD  ? F GLU 134 CD  
356 1 Y 1 R GLU 125 ? OE1 ? F GLU 134 OE1 
357 1 Y 1 R GLU 125 ? OE2 ? F GLU 134 OE2 
358 1 Y 1 R GLU 127 ? CG  ? F GLU 136 CG  
359 1 Y 1 R GLU 127 ? CD  ? F GLU 136 CD  
360 1 Y 1 R GLU 127 ? OE1 ? F GLU 136 OE1 
361 1 Y 1 R GLU 127 ? OE2 ? F GLU 136 OE2 
362 1 Y 1 R GLU 128 ? CG  ? F GLU 137 CG  
363 1 Y 1 R GLU 128 ? CD  ? F GLU 137 CD  
364 1 Y 1 R GLU 128 ? OE1 ? F GLU 137 OE1 
365 1 Y 1 R GLU 128 ? OE2 ? F GLU 137 OE2 
366 1 Y 1 R SER 129 ? OG  ? F SER 138 OG  
367 1 Y 1 R ASP 215 ? CG  ? F ASP 224 CG  
368 1 Y 1 R ASP 215 ? OD1 ? F ASP 224 OD1 
369 1 Y 1 R ASP 215 ? OD2 ? F ASP 224 OD2 
370 1 Y 1 R SER 219 ? OG  ? F SER 228 OG  
371 1 Y 1 R GLU 262 ? CG  ? F GLU 271 CG  
372 1 Y 1 R GLU 262 ? CD  ? F GLU 271 CD  
373 1 Y 1 R GLU 262 ? OE1 ? F GLU 271 OE1 
374 1 Y 1 R GLU 262 ? OE2 ? F GLU 271 OE2 
375 1 Y 1 R ASP 344 ? CG  ? F ASP 353 CG  
376 1 Y 1 R ASP 344 ? OD1 ? F ASP 353 OD1 
377 1 Y 1 R ASP 344 ? OD2 ? F ASP 353 OD2 
378 1 Y 1 R LYS 346 ? CG  ? F LYS 355 CG  
379 1 Y 1 R LYS 346 ? CD  ? F LYS 355 CD  
380 1 Y 1 R LYS 346 ? CE  ? F LYS 355 CE  
381 1 Y 1 R LYS 346 ? NZ  ? F LYS 355 NZ  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9EBO 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9EBO 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9EBO 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9EBO 
_struct.title                        'Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 1)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9EBO 
_struct_keywords.text            'G protein, agonist, backbone, GLP-1, glucagon, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAS2_HUMAN P63092 ? 1 
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
1  
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2  
3 UNP GBG2_HUMAN  P59768 ? 3 NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR 5  
4 PDB 9EBO        9EBO   ? 4 ? 1  
5 UNP GLUC_BOVIN  P01272 ? 5 HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR 98 
6 UNP GLP1R_HUMAN P43220 ? 6 
;RPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRF
CTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNL
FASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQ
WIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKT
DIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLE
HLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
;
24 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9EBO A 1  ? 394 ? P63092 1  ? 394 ? 1  394 
2 2 9EBO B 2  ? 340 ? P62873 2  ? 340 ? 2  340 
3 3 9EBO G 1  ? 58  ? P59768 5  ? 62  ? 5  62  
4 4 9EBO N 1  ? 128 ? 9EBO   1  ? 128 ? 1  128 
5 5 9EBO P 1  ? 30  ? P01272 98 ? 127 ? 7  36  
6 6 9EBO R 33 ? 472 ? P43220 24 ? 463 ? 24 463 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9EBO ASN A 54  ? UNP P63092 SER 54  'engineered mutation' 54  1  
1 9EBO ALA A 226 ? UNP P63092 GLY 226 'engineered mutation' 226 2  
1 9EBO ALA A 268 ? UNP P63092 GLU 268 'engineered mutation' 268 3  
1 9EBO LYS A 271 ? UNP P63092 ASN 271 'engineered mutation' 271 4  
1 9EBO ASP A 274 ? UNP P63092 LYS 274 'engineered mutation' 274 5  
1 9EBO LYS A 280 ? UNP P63092 ARG 280 'engineered mutation' 280 6  
1 9EBO ASP A 284 ? UNP P63092 THR 284 'engineered mutation' 284 7  
1 9EBO THR A 285 ? UNP P63092 ILE 285 'engineered mutation' 285 8  
2 9EBO GLN B 1   ? UNP P62873 ?   ?   'expression tag'      1   9  
5 9EBO XCP P 12  ? UNP P01272 SER 109 conflict              18  10 
6 9EBO MET R 1   ? UNP P43220 ?   ?   'expression tag'      -8  11 
6 9EBO LYS R 2   ? UNP P43220 ?   ?   'expression tag'      -7  12 
6 9EBO THR R 3   ? UNP P43220 ?   ?   'expression tag'      -6  13 
6 9EBO ILE R 4   ? UNP P43220 ?   ?   'expression tag'      -5  14 
6 9EBO ILE R 5   ? UNP P43220 ?   ?   'expression tag'      -4  15 
6 9EBO ALA R 6   ? UNP P43220 ?   ?   'expression tag'      -3  16 
6 9EBO LEU R 7   ? UNP P43220 ?   ?   'expression tag'      -2  17 
6 9EBO SER R 8   ? UNP P43220 ?   ?   'expression tag'      -1  18 
6 9EBO TYR R 9   ? UNP P43220 ?   ?   'expression tag'      0   19 
6 9EBO ILE R 10  ? UNP P43220 ?   ?   'expression tag'      1   20 
6 9EBO PHE R 11  ? UNP P43220 ?   ?   'expression tag'      2   21 
6 9EBO CYS R 12  ? UNP P43220 ?   ?   'expression tag'      3   22 
6 9EBO LEU R 13  ? UNP P43220 ?   ?   'expression tag'      4   23 
6 9EBO VAL R 14  ? UNP P43220 ?   ?   'expression tag'      5   24 
6 9EBO PHE R 15  ? UNP P43220 ?   ?   'expression tag'      6   25 
6 9EBO ALA R 16  ? UNP P43220 ?   ?   'expression tag'      7   26 
6 9EBO ASP R 17  ? UNP P43220 ?   ?   'expression tag'      8   27 
6 9EBO TYR R 18  ? UNP P43220 ?   ?   'expression tag'      9   28 
6 9EBO LYS R 19  ? UNP P43220 ?   ?   'expression tag'      10  29 
6 9EBO ASP R 20  ? UNP P43220 ?   ?   'expression tag'      11  30 
6 9EBO ASP R 21  ? UNP P43220 ?   ?   'expression tag'      12  31 
6 9EBO ASP R 22  ? UNP P43220 ?   ?   'expression tag'      13  32 
6 9EBO ASP R 23  ? UNP P43220 ?   ?   'expression tag'      14  33 
6 9EBO LEU R 24  ? UNP P43220 ?   ?   'expression tag'      15  34 
6 9EBO GLU R 25  ? UNP P43220 ?   ?   'expression tag'      16  35 
6 9EBO VAL R 26  ? UNP P43220 ?   ?   'expression tag'      17  36 
6 9EBO LEU R 27  ? UNP P43220 ?   ?   'expression tag'      18  37 
6 9EBO PHE R 28  ? UNP P43220 ?   ?   'expression tag'      19  38 
6 9EBO GLN R 29  ? UNP P43220 ?   ?   'expression tag'      20  39 
6 9EBO GLY R 30  ? UNP P43220 ?   ?   'expression tag'      21  40 
6 9EBO PRO R 31  ? UNP P43220 ?   ?   'expression tag'      22  41 
6 9EBO ALA R 32  ? UNP P43220 ?   ?   'expression tag'      23  42 
6 9EBO PHE R 269 ? UNP P43220 LEU 260 conflict              260 43 
6 9EBO PRO R 473 ? UNP P43220 ?   ?   'expression tag'      464 44 
6 9EBO ALA R 474 ? UNP P43220 ?   ?   'expression tag'      465 45 
6 9EBO GLY R 475 ? UNP P43220 ?   ?   'expression tag'      466 46 
6 9EBO LEU R 476 ? UNP P43220 ?   ?   'expression tag'      467 47 
6 9EBO GLU R 477 ? UNP P43220 ?   ?   'expression tag'      468 48 
6 9EBO VAL R 478 ? UNP P43220 ?   ?   'expression tag'      469 49 
6 9EBO LEU R 479 ? UNP P43220 ?   ?   'expression tag'      470 50 
6 9EBO PHE R 480 ? UNP P43220 ?   ?   'expression tag'      471 51 
6 9EBO GLN R 481 ? UNP P43220 ?   ?   'expression tag'      472 52 
6 9EBO GLY R 482 ? UNP P43220 ?   ?   'expression tag'      473 53 
6 9EBO PRO R 483 ? UNP P43220 ?   ?   'expression tag'      474 54 
6 9EBO HIS R 484 ? UNP P43220 ?   ?   'expression tag'      475 55 
6 9EBO HIS R 485 ? UNP P43220 ?   ?   'expression tag'      476 56 
6 9EBO HIS R 486 ? UNP P43220 ?   ?   'expression tag'      477 57 
6 9EBO HIS R 487 ? UNP P43220 ?   ?   'expression tag'      478 58 
6 9EBO HIS R 488 ? UNP P43220 ?   ?   'expression tag'      479 59 
6 9EBO HIS R 489 ? UNP P43220 ?   ?   'expression tag'      480 60 
6 9EBO HIS R 490 ? UNP P43220 ?   ?   'expression tag'      481 61 
6 9EBO HIS R 491 ? UNP P43220 ?   ?   'expression tag'      482 62 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 16  ? ALA A 39  ? GLU A 16  ALA A 39  1 ? 24 
HELX_P HELX_P2  AA2 GLY A 49  ? SER A 51  ? GLY A 49  SER A 51  5 ? 3  
HELX_P HELX_P3  AA3 GLY A 52  ? ARG A 61  ? GLY A 52  ARG A 61  1 ? 10 
HELX_P HELX_P4  AA4 TRP A 234 ? ASN A 239 ? TRP A 234 ASN A 239 5 ? 6  
HELX_P HELX_P5  AA5 ALA A 249 ? TYR A 253 ? ALA A 249 TYR A 253 5 ? 5  
HELX_P HELX_P6  AA6 ASN A 264 ? ASN A 278 ? ASN A 264 ASN A 278 1 ? 15 
HELX_P HELX_P7  AA7 ASN A 279 ? ARG A 283 ? ASN A 279 ARG A 283 5 ? 5  
HELX_P HELX_P8  AA8 LYS A 293 ? ALA A 303 ? LYS A 293 ALA A 303 1 ? 11 
HELX_P HELX_P9  AA9 LYS A 307 ? PHE A 312 ? LYS A 307 PHE A 312 1 ? 6  
HELX_P HELX_P10 AB1 PRO A 313 ? ALA A 316 ? PRO A 313 ALA A 316 5 ? 4  
HELX_P HELX_P11 AB2 ASP A 331 ? THR A 350 ? ASP A 331 THR A 350 1 ? 20 
HELX_P HELX_P12 AB3 GLU A 370 ? TYR A 391 ? GLU A 370 TYR A 391 1 ? 22 
HELX_P HELX_P13 AB4 ASP B 5   ? CYS B 25  ? ASP B 5   CYS B 25  1 ? 21 
HELX_P HELX_P14 AB5 THR B 29  ? THR B 34  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P15 AB6 ILE C 5   ? ASN C 20  ? ILE G 9   ASN G 24  1 ? 16 
HELX_P HELX_P16 AB7 LYS C 25  ? HIS C 40  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P17 AB8 ALA C 41  ? ASP C 44  ? ALA G 45  ASP G 48  5 ? 4  
HELX_P HELX_P18 AB9 THR D 28  ? TYR D 32  ? THR N 28  TYR N 32  5 ? 5  
HELX_P HELX_P19 AC1 LYS D 87  ? THR D 91  ? LYS N 87  THR N 91  5 ? 5  
HELX_P HELX_P20 AC2 ALA E 2   ? LYS E 28  ? ALA P 8   LYS P 34  1 ? 27 
HELX_P HELX_P21 AC3 SER F 40  ? ASP F 62  ? SER R 31  ASP R 53  1 ? 23 
HELX_P HELX_P22 AC4 GLU F 148 ? PHE F 178 ? GLU R 139 PHE R 169 1 ? 31 
HELX_P HELX_P23 AC5 CYS F 183 ? TYR F 214 ? CYS R 174 TYR R 205 1 ? 32 
HELX_P HELX_P24 AC6 SER F 215 ? ASP F 224 ? SER R 206 ASP R 215 1 ? 10 
HELX_P HELX_P25 AC7 SER F 232 ? ALA F 265 ? SER R 223 ALA R 256 1 ? 34 
HELX_P HELX_P26 AC8 SER F 270 ? GLU F 301 ? SER R 261 GLU R 292 1 ? 32 
HELX_P HELX_P27 AC9 GLU F 303 ? THR F 307 ? GLU R 294 THR R 298 5 ? 5  
HELX_P HELX_P28 AD1 ASN F 311 ? ILE F 318 ? ASN R 302 ILE R 309 5 ? 8  
HELX_P HELX_P29 AD2 ARG F 319 ? ASN F 347 ? ARG R 310 ASN R 338 1 ? 29 
HELX_P HELX_P30 AD3 ILE F 354 ? GLY F 370 ? ILE R 345 GLY R 361 1 ? 17 
HELX_P HELX_P31 AD4 THR F 371 ? PHE F 376 ? THR R 362 PHE R 367 5 ? 6  
HELX_P HELX_P32 AD5 MET F 380 ? ALA F 384 ? MET R 371 ALA R 375 5 ? 5  
HELX_P HELX_P33 AD6 ARG F 385 ? PHE F 413 ? ARG R 376 PHE R 404 1 ? 29 
HELX_P HELX_P34 AD7 ASN F 415 ? GLU F 432 ? ASN R 406 GLU R 423 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? D CYS 22  SG ? ? ? 1_555 D CYS 96  SG ? ? N CYS 22  N CYS 96  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2 disulf ?    ? D CYS 99  SG ? ? ? 1_555 D CYS 107 SG ? ? N CYS 99  N CYS 107 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf3 disulf ?    ? F CYS 55  SG ? ? ? 1_555 F CYS 80  SG ? ? R CYS 46  R CYS 71  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf4 disulf ?    ? F CYS 71  SG ? ? ? 1_555 F CYS 113 SG ? ? R CYS 62  R CYS 104 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf5 disulf ?    ? F CYS 94  SG ? ? ? 1_555 F CYS 135 SG ? ? R CYS 85  R CYS 126 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf6 disulf ?    ? F CYS 235 SG ? ? ? 1_555 F CYS 305 SG ? ? R CYS 226 R CYS 296 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
covale1 covale both ? E SER 11  C  ? ? ? 1_555 E XCP 12  N  ? ? P SER 17  P XCP 18  1_555 ? ? ? ? ? ? ? 1.322 ? ? 
covale2 covale both ? E XCP 12  C  ? ? ? 1_555 E TYR 13  N  ? ? P XCP 18  P TYR 19  1_555 ? ? ? ? ? ? ? 1.328 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 XCP E 12  ? .   . .   . XCP P 18  ? 1_555 .   . .   . .     .  .  DPR 1 XCP 'Beta-amino acid' 'Named protein modification' 
2 CYS D 22  ? CYS D 96  ? CYS N 22  ? 1_555 CYS N 96  ? 1_555 SG SG .   . .   None              'Disulfide bridge'           
3 CYS D 99  ? CYS D 107 ? CYS N 99  ? 1_555 CYS N 107 ? 1_555 SG SG .   . .   None              'Disulfide bridge'           
4 CYS F 55  ? CYS F 80  ? CYS R 46  ? 1_555 CYS R 71  ? 1_555 SG SG .   . .   None              'Disulfide bridge'           
5 CYS F 71  ? CYS F 113 ? CYS R 62  ? 1_555 CYS R 104 ? 1_555 SG SG .   . .   None              'Disulfide bridge'           
6 CYS F 94  ? CYS F 135 ? CYS R 85  ? 1_555 CYS R 126 ? 1_555 SG SG .   . .   None              'Disulfide bridge'           
7 CYS F 235 ? CYS F 305 ? CYS R 226 ? 1_555 CYS R 296 ? 1_555 SG SG .   . .   None              'Disulfide bridge'           
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 6 ? 
AB3 ? 2 ? 
AB4 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 207 ? VAL A 214 ? ILE A 207 VAL A 214 
AA1 2 VAL A 217 ? VAL A 224 ? VAL A 217 VAL A 224 
AA1 3 THR A 40  ? GLY A 47  ? THR A 40  GLY A 47  
AA1 4 ALA A 243 ? VAL A 248 ? ALA A 243 VAL A 248 
AA1 5 SER A 286 ? LEU A 291 ? SER A 286 LEU A 291 
AA1 6 CYS A 359 ? PHE A 363 ? CYS A 359 PHE A 363 
AA2 1 ILE B 58  ? TRP B 63  ? ILE B 58  TRP B 63  
AA2 2 LEU B 69  ? SER B 74  ? LEU B 69  SER B 74  
AA2 3 LYS B 78  ? ASP B 83  ? LYS B 78  ASP B 83  
AA2 4 ASN B 88  ? PRO B 94  ? ASN B 88  PRO B 94  
AA3 1 VAL B 100 ? TYR B 105 ? VAL B 100 TYR B 105 
AA3 2 TYR B 111 ? GLY B 116 ? TYR B 111 GLY B 116 
AA3 3 ILE B 120 ? ASN B 125 ? ILE B 120 ASN B 125 
AA3 4 ARG B 134 ? ALA B 140 ? ARG B 134 ALA B 140 
AA4 1 LEU B 146 ? ASP B 153 ? LEU B 146 ASP B 153 
AA4 2 GLN B 156 ? SER B 161 ? GLN B 156 SER B 161 
AA4 3 THR B 165 ? ASP B 170 ? THR B 165 ASP B 170 
AA4 4 GLN B 176 ? PHE B 180 ? GLN B 176 PHE B 180 
AA5 1 VAL B 187 ? LEU B 192 ? VAL B 187 LEU B 192 
AA5 2 LEU B 198 ? ALA B 203 ? LEU B 198 ALA B 203 
AA5 3 SER B 207 ? ASP B 212 ? SER B 207 ASP B 212 
AA5 4 CYS B 218 ? THR B 223 ? CYS B 218 THR B 223 
AA6 1 ILE B 229 ? PHE B 234 ? ILE B 229 PHE B 234 
AA6 2 PHE B 241 ? SER B 245 ? PHE B 241 SER B 245 
AA6 3 CYS B 250 ? ASP B 254 ? CYS B 250 ASP B 254 
AA6 4 GLN B 259 ? TYR B 264 ? GLN B 259 TYR B 264 
AA7 1 ILE B 273 ? PHE B 278 ? ILE B 273 PHE B 278 
AA7 2 LEU B 284 ? TYR B 289 ? LEU B 284 TYR B 289 
AA7 3 ASN B 295 ? ASP B 298 ? ASN B 295 ASP B 298 
AA7 4 ARG B 304 ? VAL B 307 ? ARG B 304 VAL B 307 
AA8 1 GLY B 319 ? VAL B 320 ? GLY B 319 VAL B 320 
AA8 2 VAL B 327 ? GLY B 330 ? VAL B 327 GLY B 330 
AA8 3 LEU B 336 ? TRP B 339 ? LEU B 336 TRP B 339 
AA9 1 GLN D 3   ? SER D 7   ? GLN N 3   SER N 7   
AA9 2 SER D 21  ? SER D 25  ? SER N 21  SER N 25  
AA9 3 THR D 78  ? MET D 83  ? THR N 78  MET N 83  
AA9 4 LEU D 18  ? ARG D 19  ? LEU N 18  ARG N 19  
AB1 1 GLN D 3   ? SER D 7   ? GLN N 3   SER N 7   
AB1 2 SER D 21  ? SER D 25  ? SER N 21  SER N 25  
AB1 3 THR D 78  ? MET D 83  ? THR N 78  MET N 83  
AB1 4 THR D 69  ? ASP D 73  ? THR N 69  ASP N 73  
AB2 1 GLY D 10  ? LEU D 11  ? GLY N 10  LEU N 11  
AB2 2 THR D 122 ? THR D 125 ? THR N 122 THR N 125 
AB2 3 ALA D 92  ? ARG D 98  ? ALA N 92  ARG N 98  
AB2 4 MET D 34  ? GLN D 39  ? MET N 34  GLN N 39  
AB2 5 SER D 49  ? ILE D 51  ? SER N 49  ILE N 51  
AB2 6 ILE D 58  ? TYR D 60  ? ILE N 58  TYR N 60  
AB3 1 THR F 74  ? PHE F 75  ? THR R 65  PHE R 66  
AB3 2 CYS F 80  ? TRP F 81  ? CYS R 71  TRP R 72  
AB4 1 SER F 88  ? SER F 93  ? SER R 79  SER R 84  
AB4 2 HIS F 108 ? CYS F 113 ? HIS R 99  CYS R 104 
AB4 3 ARG F 130 ? ASP F 131 ? ARG R 121 ASP R 122 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 212 ? N PHE A 212 O PHE A 219 ? O PHE A 219 
AA1 2 3 O HIS A 220 ? O HIS A 220 N LEU A 43  ? N LEU A 43  
AA1 3 4 N LEU A 44  ? N LEU A 44  O ILE A 245 ? O ILE A 245 
AA1 4 5 N ILE A 244 ? N ILE A 244 O ILE A 288 ? O ILE A 288 
AA1 5 6 N LEU A 291 ? N LEU A 291 O HIS A 362 ? O HIS A 362 
AA2 1 2 N HIS B 62  ? N HIS B 62  O VAL B 71  ? O VAL B 71  
AA2 2 3 N LEU B 70  ? N LEU B 70  O TRP B 82  ? O TRP B 82  
AA2 3 4 N LEU B 79  ? N LEU B 79  O ILE B 93  ? O ILE B 93  
AA3 1 2 N MET B 101 ? N MET B 101 O GLY B 115 ? O GLY B 115 
AA3 2 3 N VAL B 112 ? N VAL B 112 O TYR B 124 ? O TYR B 124 
AA3 3 4 N CYS B 121 ? N CYS B 121 O LEU B 139 ? O LEU B 139 
AA4 1 2 N ARG B 150 ? N ARG B 150 O VAL B 158 ? O VAL B 158 
AA4 2 3 N THR B 159 ? N THR B 159 O ALA B 167 ? O ALA B 167 
AA4 3 4 N CYS B 166 ? N CYS B 166 O PHE B 180 ? O PHE B 180 
AA5 1 2 N MET B 188 ? N MET B 188 O GLY B 202 ? O GLY B 202 
AA5 2 3 N PHE B 199 ? N PHE B 199 O TRP B 211 ? O TRP B 211 
AA5 3 4 N LEU B 210 ? N LEU B 210 O ARG B 219 ? O ARG B 219 
AA6 1 2 N ASN B 230 ? N ASN B 230 O GLY B 244 ? O GLY B 244 
AA6 2 3 N PHE B 241 ? N PHE B 241 O PHE B 253 ? O PHE B 253 
AA6 3 4 N LEU B 252 ? N LEU B 252 O LEU B 261 ? O LEU B 261 
AA7 1 2 N THR B 274 ? N THR B 274 O GLY B 288 ? O GLY B 288 
AA7 2 3 N LEU B 285 ? N LEU B 285 O TRP B 297 ? O TRP B 297 
AA7 3 4 N VAL B 296 ? N VAL B 296 O ALA B 305 ? O ALA B 305 
AA8 1 2 N GLY B 319 ? N GLY B 319 O ALA B 328 ? O ALA B 328 
AA8 2 3 N VAL B 327 ? N VAL B 327 O TRP B 339 ? O TRP B 339 
AA9 1 2 N GLN D 5   ? N GLN N 5   O ALA D 23  ? O ALA N 23  
AA9 2 3 N CYS D 22  ? N CYS N 22  O LEU D 79  ? O LEU N 79  
AA9 3 4 O MET D 83  ? O MET N 83  N LEU D 18  ? N LEU N 18  
AB1 1 2 N GLN D 5   ? N GLN N 5   O ALA D 23  ? O ALA N 23  
AB1 2 3 N CYS D 22  ? N CYS N 22  O LEU D 79  ? O LEU N 79  
AB1 3 4 O TYR D 80  ? O TYR N 80  N SER D 71  ? N SER N 71  
AB2 1 2 N GLY D 10  ? N GLY N 10  O THR D 125 ? O THR N 125 
AB2 2 3 O VAL D 124 ? O VAL N 124 N ALA D 92  ? N ALA N 92  
AB2 3 4 O TYR D 95  ? O TYR N 95  N VAL D 37  ? N VAL N 37  
AB2 4 5 N TRP D 36  ? N TRP N 36  O SER D 49  ? O SER N 49  
AB2 5 6 N ASP D 50  ? N ASP N 50  O SER D 59  ? O SER N 59  
AB3 1 2 N THR F 74  ? N THR R 65  O TRP F 81  ? O TRP R 72  
AB4 1 2 N VAL F 90  ? N VAL R 81  O ARG F 111 ? O ARG R 102 
AB4 2 3 N TYR F 110 ? N TYR R 101 O ASP F 131 ? O ASP R 122 
# 
_pdbx_entry_details.entry_id                   9EBO 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 232 ? ? -69.58  2.65   
2  1 LYS A 293 ? ? -141.62 44.74  
3  1 PHE A 312 ? ? -153.02 87.62  
4  1 THR A 320 ? ? -38.87  125.21 
5  1 THR B 34  ? ? -91.45  30.36  
6  1 CYS B 148 ? ? -170.71 148.71 
7  1 SER B 191 ? ? -160.30 117.91 
8  1 CYS B 233 ? ? -170.39 142.02 
9  1 PHE B 235 ? ? -46.56  150.40 
10 1 SER B 277 ? ? -171.91 141.66 
11 1 PHE B 292 ? ? 80.10   9.42   
12 1 ALA B 302 ? ? 70.27   -3.18  
13 1 SER B 334 ? ? 74.90   32.29  
14 1 PHE N 103 ? ? 67.82   -0.74  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   SER 
_pdbx_validate_peptide_omega.auth_asym_id_1   P 
_pdbx_validate_peptide_omega.auth_seq_id_1    17 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   XCP 
_pdbx_validate_peptide_omega.auth_asym_id_2   P 
_pdbx_validate_peptide_omega.auth_seq_id_2    18 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            139.97 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9EBO 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  6x18 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                6x18 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9EBO 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.13 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               187621 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Hetero-6-mer of peptide 2 (GLP-1 (ACPC-18)) bound to GLP-1R/G-alpha-S complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5, 6' 
# 
_em_imaging.entry_id                        9EBO 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             700 
_em_imaging.nominal_defocus_max             1400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'UltrAuFoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9EBO 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9EBO 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9EBO 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLY 2   ? A GLY 2   
3   1 Y 1 A CYS 3   ? A CYS 3   
4   1 Y 1 A LEU 4   ? A LEU 4   
5   1 Y 1 A GLY 5   ? A GLY 5   
6   1 Y 1 A ASN 6   ? A ASN 6   
7   1 Y 1 A SER 7   ? A SER 7   
8   1 Y 1 A LYS 8   ? A LYS 8   
9   1 Y 1 A THR 9   ? A THR 9   
10  1 Y 1 A GLU 10  ? A GLU 10  
11  1 Y 1 A ASP 11  ? A ASP 11  
12  1 Y 1 A GLN 12  ? A GLN 12  
13  1 Y 1 A ARG 13  ? A ARG 13  
14  1 Y 1 A ASN 14  ? A ASN 14  
15  1 Y 1 A GLU 15  ? A GLU 15  
16  1 Y 1 A ILE 62  ? A ILE 62  
17  1 Y 1 A LEU 63  ? A LEU 63  
18  1 Y 1 A HIS 64  ? A HIS 64  
19  1 Y 1 A VAL 65  ? A VAL 65  
20  1 Y 1 A ASN 66  ? A ASN 66  
21  1 Y 1 A GLY 67  ? A GLY 67  
22  1 Y 1 A PHE 68  ? A PHE 68  
23  1 Y 1 A ASN 69  ? A ASN 69  
24  1 Y 1 A GLY 70  ? A GLY 70  
25  1 Y 1 A GLU 71  ? A GLU 71  
26  1 Y 1 A GLY 72  ? A GLY 72  
27  1 Y 1 A GLY 73  ? A GLY 73  
28  1 Y 1 A GLU 74  ? A GLU 74  
29  1 Y 1 A GLU 75  ? A GLU 75  
30  1 Y 1 A ASP 76  ? A ASP 76  
31  1 Y 1 A PRO 77  ? A PRO 77  
32  1 Y 1 A GLN 78  ? A GLN 78  
33  1 Y 1 A ALA 79  ? A ALA 79  
34  1 Y 1 A ALA 80  ? A ALA 80  
35  1 Y 1 A ARG 81  ? A ARG 81  
36  1 Y 1 A SER 82  ? A SER 82  
37  1 Y 1 A ASN 83  ? A ASN 83  
38  1 Y 1 A SER 84  ? A SER 84  
39  1 Y 1 A ASP 85  ? A ASP 85  
40  1 Y 1 A GLY 86  ? A GLY 86  
41  1 Y 1 A GLU 87  ? A GLU 87  
42  1 Y 1 A LYS 88  ? A LYS 88  
43  1 Y 1 A ALA 89  ? A ALA 89  
44  1 Y 1 A THR 90  ? A THR 90  
45  1 Y 1 A LYS 91  ? A LYS 91  
46  1 Y 1 A VAL 92  ? A VAL 92  
47  1 Y 1 A GLN 93  ? A GLN 93  
48  1 Y 1 A ASP 94  ? A ASP 94  
49  1 Y 1 A ILE 95  ? A ILE 95  
50  1 Y 1 A LYS 96  ? A LYS 96  
51  1 Y 1 A ASN 97  ? A ASN 97  
52  1 Y 1 A ASN 98  ? A ASN 98  
53  1 Y 1 A LEU 99  ? A LEU 99  
54  1 Y 1 A LYS 100 ? A LYS 100 
55  1 Y 1 A GLU 101 ? A GLU 101 
56  1 Y 1 A ALA 102 ? A ALA 102 
57  1 Y 1 A ILE 103 ? A ILE 103 
58  1 Y 1 A GLU 104 ? A GLU 104 
59  1 Y 1 A THR 105 ? A THR 105 
60  1 Y 1 A ILE 106 ? A ILE 106 
61  1 Y 1 A VAL 107 ? A VAL 107 
62  1 Y 1 A ALA 108 ? A ALA 108 
63  1 Y 1 A ALA 109 ? A ALA 109 
64  1 Y 1 A MET 110 ? A MET 110 
65  1 Y 1 A SER 111 ? A SER 111 
66  1 Y 1 A ASN 112 ? A ASN 112 
67  1 Y 1 A LEU 113 ? A LEU 113 
68  1 Y 1 A VAL 114 ? A VAL 114 
69  1 Y 1 A PRO 115 ? A PRO 115 
70  1 Y 1 A PRO 116 ? A PRO 116 
71  1 Y 1 A VAL 117 ? A VAL 117 
72  1 Y 1 A GLU 118 ? A GLU 118 
73  1 Y 1 A LEU 119 ? A LEU 119 
74  1 Y 1 A ALA 120 ? A ALA 120 
75  1 Y 1 A ASN 121 ? A ASN 121 
76  1 Y 1 A PRO 122 ? A PRO 122 
77  1 Y 1 A GLU 123 ? A GLU 123 
78  1 Y 1 A ASN 124 ? A ASN 124 
79  1 Y 1 A GLN 125 ? A GLN 125 
80  1 Y 1 A PHE 126 ? A PHE 126 
81  1 Y 1 A ARG 127 ? A ARG 127 
82  1 Y 1 A VAL 128 ? A VAL 128 
83  1 Y 1 A ASP 129 ? A ASP 129 
84  1 Y 1 A TYR 130 ? A TYR 130 
85  1 Y 1 A ILE 131 ? A ILE 131 
86  1 Y 1 A LEU 132 ? A LEU 132 
87  1 Y 1 A SER 133 ? A SER 133 
88  1 Y 1 A VAL 134 ? A VAL 134 
89  1 Y 1 A MET 135 ? A MET 135 
90  1 Y 1 A ASN 136 ? A ASN 136 
91  1 Y 1 A VAL 137 ? A VAL 137 
92  1 Y 1 A PRO 138 ? A PRO 138 
93  1 Y 1 A ASP 139 ? A ASP 139 
94  1 Y 1 A PHE 140 ? A PHE 140 
95  1 Y 1 A ASP 141 ? A ASP 141 
96  1 Y 1 A PHE 142 ? A PHE 142 
97  1 Y 1 A PRO 143 ? A PRO 143 
98  1 Y 1 A PRO 144 ? A PRO 144 
99  1 Y 1 A GLU 145 ? A GLU 145 
100 1 Y 1 A PHE 146 ? A PHE 146 
101 1 Y 1 A TYR 147 ? A TYR 147 
102 1 Y 1 A GLU 148 ? A GLU 148 
103 1 Y 1 A HIS 149 ? A HIS 149 
104 1 Y 1 A ALA 150 ? A ALA 150 
105 1 Y 1 A LYS 151 ? A LYS 151 
106 1 Y 1 A ALA 152 ? A ALA 152 
107 1 Y 1 A LEU 153 ? A LEU 153 
108 1 Y 1 A TRP 154 ? A TRP 154 
109 1 Y 1 A GLU 155 ? A GLU 155 
110 1 Y 1 A ASP 156 ? A ASP 156 
111 1 Y 1 A GLU 157 ? A GLU 157 
112 1 Y 1 A GLY 158 ? A GLY 158 
113 1 Y 1 A VAL 159 ? A VAL 159 
114 1 Y 1 A ARG 160 ? A ARG 160 
115 1 Y 1 A ALA 161 ? A ALA 161 
116 1 Y 1 A CYS 162 ? A CYS 162 
117 1 Y 1 A TYR 163 ? A TYR 163 
118 1 Y 1 A GLU 164 ? A GLU 164 
119 1 Y 1 A ARG 165 ? A ARG 165 
120 1 Y 1 A SER 166 ? A SER 166 
121 1 Y 1 A ASN 167 ? A ASN 167 
122 1 Y 1 A GLU 168 ? A GLU 168 
123 1 Y 1 A TYR 169 ? A TYR 169 
124 1 Y 1 A GLN 170 ? A GLN 170 
125 1 Y 1 A LEU 171 ? A LEU 171 
126 1 Y 1 A ILE 172 ? A ILE 172 
127 1 Y 1 A ASP 173 ? A ASP 173 
128 1 Y 1 A CYS 174 ? A CYS 174 
129 1 Y 1 A ALA 175 ? A ALA 175 
130 1 Y 1 A GLN 176 ? A GLN 176 
131 1 Y 1 A TYR 177 ? A TYR 177 
132 1 Y 1 A PHE 178 ? A PHE 178 
133 1 Y 1 A LEU 179 ? A LEU 179 
134 1 Y 1 A ASP 180 ? A ASP 180 
135 1 Y 1 A LYS 181 ? A LYS 181 
136 1 Y 1 A ILE 182 ? A ILE 182 
137 1 Y 1 A ASP 183 ? A ASP 183 
138 1 Y 1 A VAL 184 ? A VAL 184 
139 1 Y 1 A ILE 185 ? A ILE 185 
140 1 Y 1 A LYS 186 ? A LYS 186 
141 1 Y 1 A GLN 187 ? A GLN 187 
142 1 Y 1 A ALA 188 ? A ALA 188 
143 1 Y 1 A ASP 189 ? A ASP 189 
144 1 Y 1 A TYR 190 ? A TYR 190 
145 1 Y 1 A VAL 191 ? A VAL 191 
146 1 Y 1 A PRO 192 ? A PRO 192 
147 1 Y 1 A SER 193 ? A SER 193 
148 1 Y 1 A ASP 194 ? A ASP 194 
149 1 Y 1 A GLN 195 ? A GLN 195 
150 1 Y 1 A ASP 196 ? A ASP 196 
151 1 Y 1 A LEU 197 ? A LEU 197 
152 1 Y 1 A LEU 198 ? A LEU 198 
153 1 Y 1 A ARG 199 ? A ARG 199 
154 1 Y 1 A CYS 200 ? A CYS 200 
155 1 Y 1 A ARG 201 ? A ARG 201 
156 1 Y 1 A VAL 202 ? A VAL 202 
157 1 Y 1 A LEU 203 ? A LEU 203 
158 1 Y 1 A MET 255 ? A MET 255 
159 1 Y 1 A VAL 256 ? A VAL 256 
160 1 Y 1 A ILE 257 ? A ILE 257 
161 1 Y 1 A ARG 258 ? A ARG 258 
162 1 Y 1 A GLU 259 ? A GLU 259 
163 1 Y 1 A ASP 260 ? A ASP 260 
164 1 Y 1 A ASN 261 ? A ASN 261 
165 1 Y 1 B GLN 1   ? B GLN 1   
166 1 Y 1 B SER 2   ? B SER 2   
167 1 Y 1 B GLU 3   ? B GLU 3   
168 1 Y 1 G ASN 5   ? C ASN 1   
169 1 Y 1 G THR 6   ? C THR 2   
170 1 Y 1 G ALA 7   ? C ALA 3   
171 1 Y 1 N SER 127 ? D SER 127 
172 1 Y 1 N SER 128 ? D SER 128 
173 1 Y 1 P GLY 35  ? E GLY 29  
174 1 Y 1 P ARG 36  ? E ARG 30  
175 1 Y 1 R MET -8  ? F MET 1   
176 1 Y 1 R LYS -7  ? F LYS 2   
177 1 Y 1 R THR -6  ? F THR 3   
178 1 Y 1 R ILE -5  ? F ILE 4   
179 1 Y 1 R ILE -4  ? F ILE 5   
180 1 Y 1 R ALA -3  ? F ALA 6   
181 1 Y 1 R LEU -2  ? F LEU 7   
182 1 Y 1 R SER -1  ? F SER 8   
183 1 Y 1 R TYR 0   ? F TYR 9   
184 1 Y 1 R ILE 1   ? F ILE 10  
185 1 Y 1 R PHE 2   ? F PHE 11  
186 1 Y 1 R CYS 3   ? F CYS 12  
187 1 Y 1 R LEU 4   ? F LEU 13  
188 1 Y 1 R VAL 5   ? F VAL 14  
189 1 Y 1 R PHE 6   ? F PHE 15  
190 1 Y 1 R ALA 7   ? F ALA 16  
191 1 Y 1 R ASP 8   ? F ASP 17  
192 1 Y 1 R TYR 9   ? F TYR 18  
193 1 Y 1 R LYS 10  ? F LYS 19  
194 1 Y 1 R ASP 11  ? F ASP 20  
195 1 Y 1 R ASP 12  ? F ASP 21  
196 1 Y 1 R ASP 13  ? F ASP 22  
197 1 Y 1 R ASP 14  ? F ASP 23  
198 1 Y 1 R LEU 15  ? F LEU 24  
199 1 Y 1 R GLU 16  ? F GLU 25  
200 1 Y 1 R VAL 17  ? F VAL 26  
201 1 Y 1 R LEU 18  ? F LEU 27  
202 1 Y 1 R PHE 19  ? F PHE 28  
203 1 Y 1 R GLN 20  ? F GLN 29  
204 1 Y 1 R GLY 21  ? F GLY 30  
205 1 Y 1 R PRO 22  ? F PRO 31  
206 1 Y 1 R ALA 23  ? F ALA 32  
207 1 Y 1 R ARG 24  ? F ARG 33  
208 1 Y 1 R PRO 25  ? F PRO 34  
209 1 Y 1 R GLN 26  ? F GLN 35  
210 1 Y 1 R GLY 27  ? F GLY 36  
211 1 Y 1 R ALA 28  ? F ALA 37  
212 1 Y 1 R THR 29  ? F THR 38  
213 1 Y 1 R LYS 130 ? F LYS 139 
214 1 Y 1 R ARG 131 ? F ARG 140 
215 1 Y 1 R GLY 132 ? F GLY 141 
216 1 Y 1 R GLU 133 ? F GLU 142 
217 1 Y 1 R ARG 134 ? F ARG 143 
218 1 Y 1 R SER 135 ? F SER 144 
219 1 Y 1 R SER 136 ? F SER 145 
220 1 Y 1 R PRO 137 ? F PRO 146 
221 1 Y 1 R GLY 216 ? F GLY 225 
222 1 Y 1 R LEU 217 ? F LEU 226 
223 1 Y 1 R LEU 218 ? F LEU 227 
224 1 Y 1 R LEU 339 ? F LEU 348 
225 1 Y 1 R MET 340 ? F MET 349 
226 1 Y 1 R CYS 341 ? F CYS 350 
227 1 Y 1 R LYS 342 ? F LYS 351 
228 1 Y 1 R THR 343 ? F THR 352 
229 1 Y 1 R HIS 424 ? F HIS 433 
230 1 Y 1 R LEU 425 ? F LEU 434 
231 1 Y 1 R HIS 426 ? F HIS 435 
232 1 Y 1 R ILE 427 ? F ILE 436 
233 1 Y 1 R GLN 428 ? F GLN 437 
234 1 Y 1 R ARG 429 ? F ARG 438 
235 1 Y 1 R ASP 430 ? F ASP 439 
236 1 Y 1 R SER 431 ? F SER 440 
237 1 Y 1 R SER 432 ? F SER 441 
238 1 Y 1 R MET 433 ? F MET 442 
239 1 Y 1 R LYS 434 ? F LYS 443 
240 1 Y 1 R PRO 435 ? F PRO 444 
241 1 Y 1 R LEU 436 ? F LEU 445 
242 1 Y 1 R LYS 437 ? F LYS 446 
243 1 Y 1 R CYS 438 ? F CYS 447 
244 1 Y 1 R PRO 439 ? F PRO 448 
245 1 Y 1 R THR 440 ? F THR 449 
246 1 Y 1 R SER 441 ? F SER 450 
247 1 Y 1 R SER 442 ? F SER 451 
248 1 Y 1 R LEU 443 ? F LEU 452 
249 1 Y 1 R SER 444 ? F SER 453 
250 1 Y 1 R SER 445 ? F SER 454 
251 1 Y 1 R GLY 446 ? F GLY 455 
252 1 Y 1 R ALA 447 ? F ALA 456 
253 1 Y 1 R THR 448 ? F THR 457 
254 1 Y 1 R ALA 449 ? F ALA 458 
255 1 Y 1 R GLY 450 ? F GLY 459 
256 1 Y 1 R SER 451 ? F SER 460 
257 1 Y 1 R SER 452 ? F SER 461 
258 1 Y 1 R MET 453 ? F MET 462 
259 1 Y 1 R TYR 454 ? F TYR 463 
260 1 Y 1 R THR 455 ? F THR 464 
261 1 Y 1 R ALA 456 ? F ALA 465 
262 1 Y 1 R THR 457 ? F THR 466 
263 1 Y 1 R CYS 458 ? F CYS 467 
264 1 Y 1 R GLN 459 ? F GLN 468 
265 1 Y 1 R ALA 460 ? F ALA 469 
266 1 Y 1 R SER 461 ? F SER 470 
267 1 Y 1 R CYS 462 ? F CYS 471 
268 1 Y 1 R SER 463 ? F SER 472 
269 1 Y 1 R PRO 464 ? F PRO 473 
270 1 Y 1 R ALA 465 ? F ALA 474 
271 1 Y 1 R GLY 466 ? F GLY 475 
272 1 Y 1 R LEU 467 ? F LEU 476 
273 1 Y 1 R GLU 468 ? F GLU 477 
274 1 Y 1 R VAL 469 ? F VAL 478 
275 1 Y 1 R LEU 470 ? F LEU 479 
276 1 Y 1 R PHE 471 ? F PHE 480 
277 1 Y 1 R GLN 472 ? F GLN 481 
278 1 Y 1 R GLY 473 ? F GLY 482 
279 1 Y 1 R PRO 474 ? F PRO 483 
280 1 Y 1 R HIS 475 ? F HIS 484 
281 1 Y 1 R HIS 476 ? F HIS 485 
282 1 Y 1 R HIS 477 ? F HIS 486 
283 1 Y 1 R HIS 478 ? F HIS 487 
284 1 Y 1 R HIS 479 ? F HIS 488 
285 1 Y 1 R HIS 480 ? F HIS 489 
286 1 Y 1 R HIS 481 ? F HIS 490 
287 1 Y 1 R HIS 482 ? F HIS 491 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
XCP N    N N N 388 
XCP CB   C N S 389 
XCP CG   C N N 390 
XCP CD   C N N 391 
XCP CE   C N N 392 
XCP CA   C N S 393 
XCP C    C N N 394 
XCP O    O N N 395 
XCP H    H N N 396 
XCP HB   H N N 397 
XCP HG   H N N 398 
XCP HGA  H N N 399 
XCP HD   H N N 400 
XCP HDA  H N N 401 
XCP HE   H N N 402 
XCP HEA  H N N 403 
XCP HA   H N N 404 
XCP H2   H N N 405 
XCP OXT  O N N 406 
XCP HXT  H N N 407 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
XCP N   H    sing N N 374 
XCP N   H2   sing N N 375 
XCP CB  N    sing N N 376 
XCP CB  CG   sing N N 377 
XCP CG  HGA  sing N N 378 
XCP CD  CG   sing N N 379 
XCP CD  HD   sing N N 380 
XCP CE  CD   sing N N 381 
XCP CE  CA   sing N N 382 
XCP CE  HE   sing N N 383 
XCP CA  CB   sing N N 384 
XCP CA  HA   sing N N 385 
XCP C   CA   sing N N 386 
XCP C   OXT  sing N N 387 
XCP O   C    doub N N 388 
XCP HB  CB   sing N N 389 
XCP HG  CG   sing N N 390 
XCP HDA CD   sing N N 391 
XCP HEA CE   sing N N 392 
XCP OXT HXT  sing N N 393 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-11-12 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9EBO 
_em_admin.last_update        2025-04-16 
_em_admin.map_release_date   2025-03-26 
_em_admin.title              'Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 1)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.15 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               7.39 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     5908 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   2506249 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? crYOLO    1.7.6  
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       2.12   
MASKING                    ? 3  ? ? ? ?         ?      
'CTF CORRECTION'           ? 4  1 ? ? CTFFIND   4.1.14 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?      
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?      
'MODEL FITTING'            ? 7  ? 1 ? Coot      0.9.6  
OTHER                      ? 8  ? ? ? ?         ?      
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? cryoSPARC 3.2.0  
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? cryoSPARC 3.2.0  
CLASSIFICATION             ? 11 1 ? ? ?         ?      
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC 3.2.0  
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX    1.19.2 
# 
_em_specimen.concentration           4.3 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' GM056414       1  
'National Health and Medical Research Council (NHMRC, Australia)'                          Australia       1154434        2  
'National Health and Medical Research Council (NHMRC, Australia)'                          Australia       1155302        3  
'Australian Research Council (ARC)'                                                        Australia       IC200100052    4  
'National Health and Medical Research Council (NHMRC, Australia)'                          Australia       1150083        5  
'National Health and Medical Research Council (NHMRC, Australia)'                          Australia       1184726        6  
'National Science Foundation (NSF, United States)'                                         'United States' DGE-1747503    7  
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' 'T32 GM008349' 8  
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' 'T32 GM008505' 9  
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' 'R35 GM151985' 10 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6x18 
# 
_atom_sites.entry_id                    9EBO 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 16  ? 114.868 163.232 120.981 1.00 49.89  ? 16  GLU A N   1 
ATOM   2    C CA  . GLU A 1 16  ? 115.456 161.970 121.413 1.00 49.89  ? 16  GLU A CA  1 
ATOM   3    C C   . GLU A 1 16  ? 114.498 161.192 122.306 1.00 49.89  ? 16  GLU A C   1 
ATOM   4    O O   . GLU A 1 16  ? 114.413 159.962 122.214 1.00 49.89  ? 16  GLU A O   1 
ATOM   5    C CB  . GLU A 1 16  ? 116.775 162.230 122.138 1.00 49.89  ? 16  GLU A CB  1 
ATOM   6    C CG  . GLU A 1 16  ? 117.730 161.048 122.121 1.00 49.89  ? 16  GLU A CG  1 
ATOM   7    C CD  . GLU A 1 16  ? 117.255 159.900 122.987 1.00 49.89  ? 16  GLU A CD  1 
ATOM   8    O OE1 . GLU A 1 16  ? 116.607 160.162 124.021 1.00 49.89  ? 16  GLU A OE1 1 
ATOM   9    O OE2 . GLU A 1 16  ? 117.526 158.734 122.631 1.00 49.89  ? 16  GLU A OE2 1 
ATOM   10   N N   . LYS A 1 17  ? 113.771 161.887 123.182 1.00 44.43  ? 17  LYS A N   1 
ATOM   11   C CA  . LYS A 1 17  ? 112.826 161.199 124.056 1.00 44.43  ? 17  LYS A CA  1 
ATOM   12   C C   . LYS A 1 17  ? 111.759 160.473 123.247 1.00 44.43  ? 17  LYS A C   1 
ATOM   13   O O   . LYS A 1 17  ? 111.422 159.321 123.543 1.00 44.43  ? 17  LYS A O   1 
ATOM   14   C CB  . LYS A 1 17  ? 112.177 162.195 125.017 1.00 44.43  ? 17  LYS A CB  1 
ATOM   15   N N   . ALA A 1 18  ? 111.218 161.130 122.219 1.00 36.41  ? 18  ALA A N   1 
ATOM   16   C CA  . ALA A 1 18  ? 110.221 160.478 121.379 1.00 36.41  ? 18  ALA A CA  1 
ATOM   17   C C   . ALA A 1 18  ? 110.793 159.244 120.697 1.00 36.41  ? 18  ALA A C   1 
ATOM   18   O O   . ALA A 1 18  ? 110.061 158.284 120.435 1.00 36.41  ? 18  ALA A O   1 
ATOM   19   C CB  . ALA A 1 18  ? 109.687 161.459 120.338 1.00 36.41  ? 18  ALA A CB  1 
ATOM   20   N N   . GLN A 1 19  ? 112.090 159.251 120.394 1.00 28.85  ? 19  GLN A N   1 
ATOM   21   C CA  . GLN A 1 19  ? 112.714 158.072 119.806 1.00 28.85  ? 19  GLN A CA  1 
ATOM   22   C C   . GLN A 1 19  ? 112.829 156.944 120.822 1.00 28.85  ? 19  GLN A C   1 
ATOM   23   O O   . GLN A 1 19  ? 112.635 155.772 120.480 1.00 28.85  ? 19  GLN A O   1 
ATOM   24   C CB  . GLN A 1 19  ? 114.092 158.432 119.254 1.00 28.85  ? 19  GLN A CB  1 
ATOM   25   C CG  . GLN A 1 19  ? 114.614 157.459 118.213 1.00 28.85  ? 19  GLN A CG  1 
ATOM   26   C CD  . GLN A 1 19  ? 115.923 157.911 117.602 1.00 28.85  ? 19  GLN A CD  1 
ATOM   27   O OE1 . GLN A 1 19  ? 116.893 158.172 118.311 1.00 28.85  ? 19  GLN A OE1 1 
ATOM   28   N NE2 . GLN A 1 19  ? 115.956 158.009 116.279 1.00 28.85  ? 19  GLN A NE2 1 
ATOM   29   N N   . ARG A 1 20  ? 113.152 157.276 122.072 1.00 32.78  ? 20  ARG A N   1 
ATOM   30   C CA  . ARG A 1 20  ? 113.377 156.240 123.073 1.00 32.78  ? 20  ARG A CA  1 
ATOM   31   C C   . ARG A 1 20  ? 112.087 155.512 123.426 1.00 32.78  ? 20  ARG A C   1 
ATOM   32   O O   . ARG A 1 20  ? 112.086 154.286 123.587 1.00 32.78  ? 20  ARG A O   1 
ATOM   33   C CB  . ARG A 1 20  ? 113.998 156.851 124.326 1.00 32.78  ? 20  ARG A CB  1 
ATOM   34   N N   . GLU A 1 21  ? 110.979 156.245 123.556 1.00 25.34  ? 21  GLU A N   1 
ATOM   35   C CA  . GLU A 1 21  ? 109.732 155.615 123.977 1.00 25.34  ? 21  GLU A CA  1 
ATOM   36   C C   . GLU A 1 21  ? 109.263 154.582 122.958 1.00 25.34  ? 21  GLU A C   1 
ATOM   37   O O   . GLU A 1 21  ? 108.824 153.488 123.331 1.00 25.34  ? 21  GLU A O   1 
ATOM   38   C CB  . GLU A 1 21  ? 108.656 156.679 124.206 1.00 25.34  ? 21  GLU A CB  1 
ATOM   39   N N   . ALA A 1 22  ? 109.351 154.906 121.668 1.00 21.32  ? 22  ALA A N   1 
ATOM   40   C CA  . ALA A 1 22  ? 108.929 153.959 120.643 1.00 21.32  ? 22  ALA A CA  1 
ATOM   41   C C   . ALA A 1 22  ? 109.780 152.700 120.680 1.00 21.32  ? 22  ALA A C   1 
ATOM   42   O O   . ALA A 1 22  ? 109.262 151.586 120.542 1.00 21.32  ? 22  ALA A O   1 
ATOM   43   C CB  . ALA A 1 22  ? 108.995 154.610 119.265 1.00 21.32  ? 22  ALA A CB  1 
ATOM   44   N N   . ASN A 1 23  ? 111.093 152.853 120.869 1.00 18.38  ? 23  ASN A N   1 
ATOM   45   C CA  . ASN A 1 23  ? 111.959 151.684 120.965 1.00 18.38  ? 23  ASN A CA  1 
ATOM   46   C C   . ASN A 1 23  ? 111.518 150.778 122.105 1.00 18.38  ? 23  ASN A C   1 
ATOM   47   O O   . ASN A 1 23  ? 111.520 149.550 121.968 1.00 18.38  ? 23  ASN A O   1 
ATOM   48   C CB  . ASN A 1 23  ? 113.409 152.123 121.158 1.00 18.38  ? 23  ASN A CB  1 
ATOM   49   C CG  . ASN A 1 23  ? 114.370 150.955 121.212 1.00 18.38  ? 23  ASN A CG  1 
ATOM   50   O OD1 . ASN A 1 23  ? 113.966 149.799 121.118 1.00 18.38  ? 23  ASN A OD1 1 
ATOM   51   N ND2 . ASN A 1 23  ? 115.653 151.253 121.368 1.00 18.38  ? 23  ASN A ND2 1 
ATOM   52   N N   . LYS A 1 24  ? 111.136 151.364 123.241 1.00 18.53  ? 24  LYS A N   1 
ATOM   53   C CA  . LYS A 1 24  ? 110.597 150.563 124.333 1.00 18.53  ? 24  LYS A CA  1 
ATOM   54   C C   . LYS A 1 24  ? 109.331 149.839 123.901 1.00 18.53  ? 24  LYS A C   1 
ATOM   55   O O   . LYS A 1 24  ? 109.148 148.655 124.206 1.00 18.53  ? 24  LYS A O   1 
ATOM   56   C CB  . LYS A 1 24  ? 110.318 151.454 125.543 1.00 18.53  ? 24  LYS A CB  1 
ATOM   57   N N   . LYS A 1 25  ? 108.443 150.535 123.191 1.00 16.78  ? 25  LYS A N   1 
ATOM   58   C CA  . LYS A 1 25  ? 107.224 149.901 122.704 1.00 16.78  ? 25  LYS A CA  1 
ATOM   59   C C   . LYS A 1 25  ? 107.540 148.809 121.690 1.00 16.78  ? 25  LYS A C   1 
ATOM   60   O O   . LYS A 1 25  ? 106.942 147.729 121.724 1.00 16.78  ? 25  LYS A O   1 
ATOM   61   C CB  . LYS A 1 25  ? 106.306 150.955 122.090 1.00 16.78  ? 25  LYS A CB  1 
ATOM   62   C CG  . LYS A 1 25  ? 105.745 151.951 123.080 1.00 16.78  ? 25  LYS A CG  1 
ATOM   63   C CD  . LYS A 1 25  ? 104.868 152.969 122.377 1.00 16.78  ? 25  LYS A CD  1 
ATOM   64   C CE  . LYS A 1 25  ? 104.277 153.963 123.358 1.00 16.78  ? 25  LYS A CE  1 
ATOM   65   N NZ  . LYS A 1 25  ? 103.434 154.981 122.673 1.00 16.78  ? 25  LYS A NZ  1 
ATOM   66   N N   . ILE A 1 26  ? 108.473 149.075 120.776 1.00 16.38  ? 26  ILE A N   1 
ATOM   67   C CA  . ILE A 1 26  ? 108.849 148.070 119.786 1.00 16.38  ? 26  ILE A CA  1 
ATOM   68   C C   . ILE A 1 26  ? 109.501 146.877 120.469 1.00 16.38  ? 26  ILE A C   1 
ATOM   69   O O   . ILE A 1 26  ? 109.154 145.721 120.202 1.00 16.38  ? 26  ILE A O   1 
ATOM   70   C CB  . ILE A 1 26  ? 109.774 148.688 118.723 1.00 16.38  ? 26  ILE A CB  1 
ATOM   71   C CG1 . ILE A 1 26  ? 108.947 149.387 117.646 1.00 16.38  ? 26  ILE A CG1 1 
ATOM   72   C CG2 . ILE A 1 26  ? 110.656 147.625 118.088 1.00 16.38  ? 26  ILE A CG2 1 
ATOM   73   C CD1 . ILE A 1 26  ? 109.730 150.386 116.834 1.00 16.38  ? 26  ILE A CD1 1 
ATOM   74   N N   . GLU A 1 27  ? 110.457 147.137 121.360 1.00 17.19  ? 27  GLU A N   1 
ATOM   75   C CA  . GLU A 1 27  ? 111.128 146.046 122.055 1.00 17.19  ? 27  GLU A CA  1 
ATOM   76   C C   . GLU A 1 27  ? 110.140 145.262 122.907 1.00 17.19  ? 27  GLU A C   1 
ATOM   77   O O   . GLU A 1 27  ? 110.193 144.028 122.961 1.00 17.19  ? 27  GLU A O   1 
ATOM   78   C CB  . GLU A 1 27  ? 112.267 146.602 122.910 1.00 17.19  ? 27  GLU A CB  1 
ATOM   79   C CG  . GLU A 1 27  ? 112.948 145.598 123.832 1.00 17.19  ? 27  GLU A CG  1 
ATOM   80   C CD  . GLU A 1 27  ? 113.071 144.214 123.225 1.00 17.19  ? 27  GLU A CD  1 
ATOM   81   O OE1 . GLU A 1 27  ? 113.852 144.052 122.266 1.00 17.19  ? 27  GLU A OE1 1 
ATOM   82   O OE2 . GLU A 1 27  ? 112.407 143.283 123.723 1.00 17.19  ? 27  GLU A OE2 1 
ATOM   83   N N   . LYS A 1 28  ? 109.218 145.961 123.569 1.00 16.18  ? 28  LYS A N   1 
ATOM   84   C CA  . LYS A 1 28  ? 108.203 145.277 124.362 1.00 16.18  ? 28  LYS A CA  1 
ATOM   85   C C   . LYS A 1 28  ? 107.402 144.304 123.506 1.00 16.18  ? 28  LYS A C   1 
ATOM   86   O O   . LYS A 1 28  ? 106.951 143.262 123.994 1.00 16.18  ? 28  LYS A O   1 
ATOM   87   C CB  . LYS A 1 28  ? 107.278 146.302 125.017 1.00 16.18  ? 28  LYS A CB  1 
ATOM   88   C CG  . LYS A 1 28  ? 106.130 145.700 125.815 1.00 16.18  ? 28  LYS A CG  1 
ATOM   89   C CD  . LYS A 1 28  ? 105.199 146.776 126.363 1.00 16.18  ? 28  LYS A CD  1 
ATOM   90   C CE  . LYS A 1 28  ? 105.926 147.758 127.272 1.00 16.18  ? 28  LYS A CE  1 
ATOM   91   N NZ  . LYS A 1 28  ? 106.826 147.079 128.245 1.00 16.18  ? 28  LYS A NZ  1 
ATOM   92   N N   . GLN A 1 29  ? 107.208 144.632 122.228 1.00 17.18  ? 29  GLN A N   1 
ATOM   93   C CA  . GLN A 1 29  ? 106.464 143.742 121.344 1.00 17.18  ? 29  GLN A CA  1 
ATOM   94   C C   . GLN A 1 29  ? 107.292 142.524 120.960 1.00 17.18  ? 29  GLN A C   1 
ATOM   95   O O   . GLN A 1 29  ? 106.771 141.405 120.912 1.00 17.18  ? 29  GLN A O   1 
ATOM   96   C CB  . GLN A 1 29  ? 106.020 144.497 120.094 1.00 17.18  ? 29  GLN A CB  1 
ATOM   97   C CG  . GLN A 1 29  ? 105.092 143.708 119.191 1.00 17.18  ? 29  GLN A CG  1 
ATOM   98   C CD  . GLN A 1 29  ? 103.764 143.407 119.846 1.00 17.18  ? 29  GLN A CD  1 
ATOM   99   O OE1 . GLN A 1 29  ? 103.227 144.226 120.590 1.00 17.18  ? 29  GLN A OE1 1 
ATOM   100  N NE2 . GLN A 1 29  ? 103.221 142.229 119.569 1.00 17.18  ? 29  GLN A NE2 1 
ATOM   101  N N   . LEU A 1 30  ? 108.581 142.718 120.680 1.00 18.18  ? 30  LEU A N   1 
ATOM   102  C CA  . LEU A 1 30  ? 109.422 141.600 120.273 1.00 18.18  ? 30  LEU A CA  1 
ATOM   103  C C   . LEU A 1 30  ? 109.527 140.536 121.353 1.00 18.18  ? 30  LEU A C   1 
ATOM   104  O O   . LEU A 1 30  ? 109.887 139.394 121.048 1.00 18.18  ? 30  LEU A O   1 
ATOM   105  C CB  . LEU A 1 30  ? 110.819 142.097 119.904 1.00 18.18  ? 30  LEU A CB  1 
ATOM   106  C CG  . LEU A 1 30  ? 110.915 143.070 118.728 1.00 18.18  ? 30  LEU A CG  1 
ATOM   107  C CD1 . LEU A 1 30  ? 112.369 143.366 118.415 1.00 18.18  ? 30  LEU A CD1 1 
ATOM   108  C CD2 . LEU A 1 30  ? 110.207 142.525 117.502 1.00 18.18  ? 30  LEU A CD2 1 
ATOM   109  N N   . GLN A 1 31  ? 109.237 140.880 122.609 1.00 21.36  ? 31  GLN A N   1 
ATOM   110  C CA  . GLN A 1 31  ? 109.253 139.878 123.667 1.00 21.36  ? 31  GLN A CA  1 
ATOM   111  C C   . GLN A 1 31  ? 108.116 138.882 123.489 1.00 21.36  ? 31  GLN A C   1 
ATOM   112  O O   . GLN A 1 31  ? 108.318 137.668 123.603 1.00 21.36  ? 31  GLN A O   1 
ATOM   113  C CB  . GLN A 1 31  ? 109.162 140.558 125.035 1.00 21.36  ? 31  GLN A CB  1 
ATOM   114  C CG  . GLN A 1 31  ? 110.493 140.996 125.649 1.00 21.36  ? 31  GLN A CG  1 
ATOM   115  C CD  . GLN A 1 31  ? 111.576 139.935 125.582 1.00 21.36  ? 31  GLN A CD  1 
ATOM   116  O OE1 . GLN A 1 31  ? 111.294 138.747 125.428 1.00 21.36  ? 31  GLN A OE1 1 
ATOM   117  N NE2 . GLN A 1 31  ? 112.827 140.362 125.700 1.00 21.36  ? 31  GLN A NE2 1 
ATOM   118  N N   . LYS A 1 32  ? 106.910 139.378 123.210 1.00 21.42  ? 32  LYS A N   1 
ATOM   119  C CA  . LYS A 1 32  ? 105.781 138.480 122.992 1.00 21.42  ? 32  LYS A CA  1 
ATOM   120  C C   . LYS A 1 32  ? 105.992 137.629 121.747 1.00 21.42  ? 32  LYS A C   1 
ATOM   121  O O   . LYS A 1 32  ? 105.690 136.430 121.747 1.00 21.42  ? 32  LYS A O   1 
ATOM   122  C CB  . LYS A 1 32  ? 104.487 139.283 122.883 1.00 21.42  ? 32  LYS A CB  1 
ATOM   123  C CG  . LYS A 1 32  ? 104.077 139.944 124.187 1.00 21.42  ? 32  LYS A CG  1 
ATOM   124  C CD  . LYS A 1 32  ? 102.687 140.546 124.104 1.00 21.42  ? 32  LYS A CD  1 
ATOM   125  C CE  . LYS A 1 32  ? 102.652 141.734 123.161 1.00 21.42  ? 32  LYS A CE  1 
ATOM   126  N NZ  . LYS A 1 32  ? 101.323 142.401 123.166 1.00 21.42  ? 32  LYS A NZ  1 
ATOM   127  N N   . ASP A 1 33  ? 106.510 138.229 120.675 1.00 20.91  ? 33  ASP A N   1 
ATOM   128  C CA  . ASP A 1 33  ? 106.806 137.467 119.469 1.00 20.91  ? 33  ASP A CA  1 
ATOM   129  C C   . ASP A 1 33  ? 107.929 136.465 119.683 1.00 20.91  ? 33  ASP A C   1 
ATOM   130  O O   . ASP A 1 33  ? 108.041 135.506 118.916 1.00 20.91  ? 33  ASP A O   1 
ATOM   131  C CB  . ASP A 1 33  ? 107.174 138.412 118.326 1.00 20.91  ? 33  ASP A CB  1 
ATOM   132  C CG  . ASP A 1 33  ? 106.021 139.302 117.914 1.00 20.91  ? 33  ASP A CG  1 
ATOM   133  O OD1 . ASP A 1 33  ? 104.958 139.236 118.565 1.00 20.91  ? 33  ASP A OD1 1 
ATOM   134  O OD2 . ASP A 1 33  ? 106.177 140.067 116.939 1.00 20.91  ? 33  ASP A OD2 1 
ATOM   135  N N   . LYS A 1 34  ? 108.765 136.667 120.701 1.00 21.89  ? 34  LYS A N   1 
ATOM   136  C CA  . LYS A 1 34  ? 109.820 135.707 120.997 1.00 21.89  ? 34  LYS A CA  1 
ATOM   137  C C   . LYS A 1 34  ? 109.273 134.451 121.659 1.00 21.89  ? 34  LYS A C   1 
ATOM   138  O O   . LYS A 1 34  ? 109.848 133.371 121.496 1.00 21.89  ? 34  LYS A O   1 
ATOM   139  C CB  . LYS A 1 34  ? 110.875 136.351 121.894 1.00 21.89  ? 34  LYS A CB  1 
ATOM   140  C CG  . LYS A 1 34  ? 112.137 135.530 122.059 1.00 21.89  ? 34  LYS A CG  1 
ATOM   141  C CD  . LYS A 1 34  ? 113.041 136.135 123.120 1.00 21.89  ? 34  LYS A CD  1 
ATOM   142  C CE  . LYS A 1 34  ? 114.264 135.274 123.387 1.00 21.89  ? 34  LYS A CE  1 
ATOM   143  N NZ  . LYS A 1 34  ? 114.755 134.580 122.167 1.00 21.89  ? 34  LYS A NZ  1 
ATOM   144  N N   . GLN A 1 35  ? 108.178 134.571 122.411 1.00 27.05  ? 35  GLN A N   1 
ATOM   145  C CA  . GLN A 1 35  ? 107.570 133.397 123.024 1.00 27.05  ? 35  GLN A CA  1 
ATOM   146  C C   . GLN A 1 35  ? 106.981 132.473 121.967 1.00 27.05  ? 35  GLN A C   1 
ATOM   147  O O   . GLN A 1 35  ? 107.220 131.261 121.982 1.00 27.05  ? 35  GLN A O   1 
ATOM   148  C CB  . GLN A 1 35  ? 106.490 133.823 124.016 1.00 27.05  ? 35  GLN A CB  1 
ATOM   149  C CG  . GLN A 1 35  ? 107.019 134.219 125.381 1.00 27.05  ? 35  GLN A CG  1 
ATOM   150  C CD  . GLN A 1 35  ? 105.950 134.839 126.257 1.00 27.05  ? 35  GLN A CD  1 
ATOM   151  O OE1 . GLN A 1 35  ? 104.756 134.655 126.022 1.00 27.05  ? 35  GLN A OE1 1 
ATOM   152  N NE2 . GLN A 1 35  ? 106.374 135.580 127.273 1.00 27.05  ? 35  GLN A NE2 1 
ATOM   153  N N   . VAL A 1 36  ? 106.209 133.033 121.035 1.00 23.50  ? 36  VAL A N   1 
ATOM   154  C CA  . VAL A 1 36  ? 105.550 132.212 120.024 1.00 23.50  ? 36  VAL A CA  1 
ATOM   155  C C   . VAL A 1 36  ? 106.579 131.528 119.137 1.00 23.50  ? 36  VAL A C   1 
ATOM   156  O O   . VAL A 1 36  ? 106.452 130.341 118.815 1.00 23.50  ? 36  VAL A O   1 
ATOM   157  C CB  . VAL A 1 36  ? 104.574 133.069 119.200 1.00 23.50  ? 36  VAL A CB  1 
ATOM   158  C CG1 . VAL A 1 36  ? 104.052 132.284 118.010 1.00 23.50  ? 36  VAL A CG1 1 
ATOM   159  C CG2 . VAL A 1 36  ? 103.431 133.553 120.075 1.00 23.50  ? 36  VAL A CG2 1 
ATOM   160  N N   . TYR A 1 37  ? 107.613 132.261 118.725 1.00 20.27  ? 37  TYR A N   1 
ATOM   161  C CA  . TYR A 1 37  ? 108.622 131.677 117.848 1.00 20.27  ? 37  TYR A CA  1 
ATOM   162  C C   . TYR A 1 37  ? 109.317 130.501 118.516 1.00 20.27  ? 37  TYR A C   1 
ATOM   163  O O   . TYR A 1 37  ? 109.551 129.466 117.881 1.00 20.27  ? 37  TYR A O   1 
ATOM   164  C CB  . TYR A 1 37  ? 109.643 132.739 117.445 1.00 20.27  ? 37  TYR A CB  1 
ATOM   165  C CG  . TYR A 1 37  ? 110.716 132.228 116.513 1.00 20.27  ? 37  TYR A CG  1 
ATOM   166  C CD1 . TYR A 1 37  ? 110.505 132.174 115.143 1.00 20.27  ? 37  TYR A CD1 1 
ATOM   167  C CD2 . TYR A 1 37  ? 111.940 131.799 117.001 1.00 20.27  ? 37  TYR A CD2 1 
ATOM   168  C CE1 . TYR A 1 37  ? 111.479 131.707 114.289 1.00 20.27  ? 37  TYR A CE1 1 
ATOM   169  C CE2 . TYR A 1 37  ? 112.921 131.331 116.154 1.00 20.27  ? 37  TYR A CE2 1 
ATOM   170  C CZ  . TYR A 1 37  ? 112.685 131.289 114.800 1.00 20.27  ? 37  TYR A CZ  1 
ATOM   171  O OH  . TYR A 1 37  ? 113.661 130.823 113.953 1.00 20.27  ? 37  TYR A OH  1 
ATOM   172  N N   . ARG A 1 38  ? 109.655 130.636 119.796 1.00 23.92  ? 38  ARG A N   1 
ATOM   173  C CA  . ARG A 1 38  ? 110.382 129.595 120.508 1.00 23.92  ? 38  ARG A CA  1 
ATOM   174  C C   . ARG A 1 38  ? 109.504 128.419 120.913 1.00 23.92  ? 38  ARG A C   1 
ATOM   175  O O   . ARG A 1 38  ? 110.040 127.367 121.273 1.00 23.92  ? 38  ARG A O   1 
ATOM   176  C CB  . ARG A 1 38  ? 111.042 130.183 121.755 1.00 23.92  ? 38  ARG A CB  1 
ATOM   177  C CG  . ARG A 1 38  ? 112.123 131.201 121.454 1.00 23.92  ? 38  ARG A CG  1 
ATOM   178  C CD  . ARG A 1 38  ? 113.500 130.659 121.780 1.00 23.92  ? 38  ARG A CD  1 
ATOM   179  N NE  . ARG A 1 38  ? 114.549 131.626 121.484 1.00 23.92  ? 38  ARG A NE  1 
ATOM   180  C CZ  . ARG A 1 38  ? 115.004 131.890 120.266 1.00 23.92  ? 38  ARG A CZ  1 
ATOM   181  N NH1 . ARG A 1 38  ? 114.519 131.280 119.197 1.00 23.92  ? 38  ARG A NH1 1 
ATOM   182  N NH2 . ARG A 1 38  ? 115.971 132.792 120.117 1.00 23.92  ? 38  ARG A NH2 1 
ATOM   183  N N   . ALA A 1 39  ? 108.181 128.564 120.861 1.00 22.80  ? 39  ALA A N   1 
ATOM   184  C CA  . ALA A 1 39  ? 107.263 127.516 121.281 1.00 22.80  ? 39  ALA A CA  1 
ATOM   185  C C   . ALA A 1 39  ? 106.706 126.715 120.112 1.00 22.80  ? 39  ALA A C   1 
ATOM   186  O O   . ALA A 1 39  ? 105.764 125.940 120.301 1.00 22.80  ? 39  ALA A O   1 
ATOM   187  C CB  . ALA A 1 39  ? 106.112 128.121 122.086 1.00 22.80  ? 39  ALA A CB  1 
ATOM   188  N N   . THR A 1 40  ? 107.261 126.881 118.914 1.00 22.74  ? 40  THR A N   1 
ATOM   189  C CA  . THR A 1 40  ? 106.778 126.199 117.722 1.00 22.74  ? 40  THR A CA  1 
ATOM   190  C C   . THR A 1 40  ? 107.946 125.564 116.983 1.00 22.74  ? 40  THR A C   1 
ATOM   191  O O   . THR A 1 40  ? 109.063 126.087 116.986 1.00 22.74  ? 40  THR A O   1 
ATOM   192  C CB  . THR A 1 40  ? 106.032 127.166 116.793 1.00 22.74  ? 40  THR A CB  1 
ATOM   193  O OG1 . THR A 1 40  ? 104.924 127.744 117.492 1.00 22.74  ? 40  THR A OG1 1 
ATOM   194  C CG2 . THR A 1 40  ? 105.521 126.445 115.559 1.00 22.74  ? 40  THR A CG2 1 
ATOM   195  N N   . HIS A 1 41  ? 107.675 124.427 116.349 1.00 19.61  ? 41  HIS A N   1 
ATOM   196  C CA  . HIS A 1 41  ? 108.669 123.680 115.597 1.00 19.61  ? 41  HIS A CA  1 
ATOM   197  C C   . HIS A 1 41  ? 108.411 123.824 114.103 1.00 19.61  ? 41  HIS A C   1 
ATOM   198  O O   . HIS A 1 41  ? 107.265 123.936 113.662 1.00 19.61  ? 41  HIS A O   1 
ATOM   199  C CB  . HIS A 1 41  ? 108.650 122.200 115.979 1.00 19.61  ? 41  HIS A CB  1 
ATOM   200  C CG  . HIS A 1 41  ? 108.894 121.948 117.433 1.00 19.61  ? 41  HIS A CG  1 
ATOM   201  N ND1 . HIS A 1 41  ? 107.949 121.378 118.259 1.00 19.61  ? 41  HIS A ND1 1 
ATOM   202  C CD2 . HIS A 1 41  ? 109.978 122.185 118.209 1.00 19.61  ? 41  HIS A CD2 1 
ATOM   203  C CE1 . HIS A 1 41  ? 108.440 121.276 119.481 1.00 19.61  ? 41  HIS A CE1 1 
ATOM   204  N NE2 . HIS A 1 41  ? 109.670 121.759 119.478 1.00 19.61  ? 41  HIS A NE2 1 
ATOM   205  N N   . ARG A 1 42  ? 109.492 123.813 113.330 1.00 17.34  ? 42  ARG A N   1 
ATOM   206  C CA  . ARG A 1 42  ? 109.436 123.943 111.880 1.00 17.34  ? 42  ARG A CA  1 
ATOM   207  C C   . ARG A 1 42  ? 109.864 122.630 111.241 1.00 17.34  ? 42  ARG A C   1 
ATOM   208  O O   . ARG A 1 42  ? 110.871 122.040 111.644 1.00 17.34  ? 42  ARG A O   1 
ATOM   209  C CB  . ARG A 1 42  ? 110.335 125.081 111.396 1.00 17.34  ? 42  ARG A CB  1 
ATOM   210  C CG  . ARG A 1 42  ? 109.784 126.466 111.675 1.00 17.34  ? 42  ARG A CG  1 
ATOM   211  C CD  . ARG A 1 42  ? 110.894 127.449 111.981 1.00 17.34  ? 42  ARG A CD  1 
ATOM   212  N NE  . ARG A 1 42  ? 111.330 127.357 113.368 1.00 17.34  ? 42  ARG A NE  1 
ATOM   213  C CZ  . ARG A 1 42  ? 110.622 127.786 114.404 1.00 17.34  ? 42  ARG A CZ  1 
ATOM   214  N NH1 . ARG A 1 42  ? 109.435 128.345 114.247 1.00 17.34  ? 42  ARG A NH1 1 
ATOM   215  N NH2 . ARG A 1 42  ? 111.119 127.650 115.630 1.00 17.34  ? 42  ARG A NH2 1 
ATOM   216  N N   . LEU A 1 43  ? 109.099 122.179 110.252 1.00 17.28  ? 43  LEU A N   1 
ATOM   217  C CA  . LEU A 1 43  ? 109.349 120.915 109.578 1.00 17.28  ? 43  LEU A CA  1 
ATOM   218  C C   . LEU A 1 43  ? 109.290 121.126 108.075 1.00 17.28  ? 43  LEU A C   1 
ATOM   219  O O   . LEU A 1 43  ? 108.335 121.721 107.569 1.00 17.28  ? 43  LEU A O   1 
ATOM   220  C CB  . LEU A 1 43  ? 108.321 119.864 110.001 1.00 17.28  ? 43  LEU A CB  1 
ATOM   221  C CG  . LEU A 1 43  ? 108.375 119.431 111.466 1.00 17.28  ? 43  LEU A CG  1 
ATOM   222  C CD1 . LEU A 1 43  ? 107.221 118.503 111.774 1.00 17.28  ? 43  LEU A CD1 1 
ATOM   223  C CD2 . LEU A 1 43  ? 109.697 118.760 111.781 1.00 17.28  ? 43  LEU A CD2 1 
ATOM   224  N N   . LEU A 1 44  ? 110.303 120.636 107.365 1.00 16.03  ? 44  LEU A N   1 
ATOM   225  C CA  . LEU A 1 44  ? 110.333 120.699 105.910 1.00 16.03  ? 44  LEU A CA  1 
ATOM   226  C C   . LEU A 1 44  ? 109.865 119.369 105.339 1.00 16.03  ? 44  LEU A C   1 
ATOM   227  O O   . LEU A 1 44  ? 110.266 118.306 105.821 1.00 16.03  ? 44  LEU A O   1 
ATOM   228  C CB  . LEU A 1 44  ? 111.738 121.023 105.407 1.00 16.03  ? 44  LEU A CB  1 
ATOM   229  C CG  . LEU A 1 44  ? 111.949 120.880 103.898 1.00 16.03  ? 44  LEU A CG  1 
ATOM   230  C CD1 . LEU A 1 44  ? 111.040 121.826 103.135 1.00 16.03  ? 44  LEU A CD1 1 
ATOM   231  C CD2 . LEU A 1 44  ? 113.401 121.120 103.532 1.00 16.03  ? 44  LEU A CD2 1 
ATOM   232  N N   . LEU A 1 45  ? 109.026 119.431 104.313 1.00 21.15  ? 45  LEU A N   1 
ATOM   233  C CA  . LEU A 1 45  ? 108.447 118.244 103.688 1.00 21.15  ? 45  LEU A CA  1 
ATOM   234  C C   . LEU A 1 45  ? 109.010 118.112 102.277 1.00 21.15  ? 45  LEU A C   1 
ATOM   235  O O   . LEU A 1 45  ? 108.602 118.835 101.365 1.00 21.15  ? 45  LEU A O   1 
ATOM   236  C CB  . LEU A 1 45  ? 106.926 118.337 103.677 1.00 21.15  ? 45  LEU A CB  1 
ATOM   237  C CG  . LEU A 1 45  ? 106.179 117.119 103.141 1.00 21.15  ? 45  LEU A CG  1 
ATOM   238  C CD1 . LEU A 1 45  ? 106.564 115.866 103.895 1.00 21.15  ? 45  LEU A CD1 1 
ATOM   239  C CD2 . LEU A 1 45  ? 104.691 117.350 103.238 1.00 21.15  ? 45  LEU A CD2 1 
ATOM   240  N N   . LEU A 1 46  ? 109.949 117.184 102.103 1.00 17.25  ? 46  LEU A N   1 
ATOM   241  C CA  . LEU A 1 46  ? 110.541 116.892 100.809 1.00 17.25  ? 46  LEU A CA  1 
ATOM   242  C C   . LEU A 1 46  ? 109.921 115.623 100.230 1.00 17.25  ? 46  LEU A C   1 
ATOM   243  O O   . LEU A 1 46  ? 108.989 115.042 100.789 1.00 17.25  ? 46  LEU A O   1 
ATOM   244  C CB  . LEU A 1 46  ? 112.057 116.754 100.937 1.00 17.25  ? 46  LEU A CB  1 
ATOM   245  C CG  . LEU A 1 46  ? 112.853 118.050 100.793 1.00 17.25  ? 46  LEU A CG  1 
ATOM   246  C CD1 . LEU A 1 46  ? 114.295 117.827 101.196 1.00 17.25  ? 46  LEU A CD1 1 
ATOM   247  C CD2 . LEU A 1 46  ? 112.773 118.570 99.371  1.00 17.25  ? 46  LEU A CD2 1 
ATOM   248  N N   . GLY A 1 47  ? 110.447 115.194 99.086  1.00 21.98  ? 47  GLY A N   1 
ATOM   249  C CA  . GLY A 1 47  ? 109.965 113.993 98.435  1.00 21.98  ? 47  GLY A CA  1 
ATOM   250  C C   . GLY A 1 47  ? 109.542 114.228 97.001  1.00 21.98  ? 47  GLY A C   1 
ATOM   251  O O   . GLY A 1 47  ? 108.956 115.267 96.681  0.00 21.98  ? 47  GLY A O   1 
ATOM   252  N N   . ALA A 1 48  ? 109.832 113.265 96.128  1.00 39.01  ? 48  ALA A N   1 
ATOM   253  C CA  . ALA A 1 48  ? 109.487 113.380 94.716  1.00 39.01  ? 48  ALA A CA  1 
ATOM   254  C C   . ALA A 1 48  ? 107.987 113.583 94.542  1.00 39.01  ? 48  ALA A C   1 
ATOM   255  O O   . ALA A 1 48  ? 107.213 113.374 95.481  1.00 39.01  ? 48  ALA A O   1 
ATOM   256  C CB  . ALA A 1 48  ? 109.949 112.140 93.949  1.00 39.01  ? 48  ALA A CB  1 
ATOM   257  N N   . GLY A 1 49  ? 107.572 113.998 93.345  1.00 58.38  ? 49  GLY A N   1 
ATOM   258  C CA  . GLY A 1 49  ? 106.162 114.271 93.120  1.00 58.38  ? 49  GLY A CA  1 
ATOM   259  C C   . GLY A 1 49  ? 105.292 113.044 93.320  1.00 58.38  ? 49  GLY A C   1 
ATOM   260  O O   . GLY A 1 49  ? 104.235 113.113 93.950  1.00 58.38  ? 49  GLY A O   1 
ATOM   261  N N   . GLU A 1 50  ? 105.730 111.903 92.792  1.00 45.30  ? 50  GLU A N   1 
ATOM   262  C CA  . GLU A 1 50  ? 104.957 110.670 92.837  1.00 45.30  ? 50  GLU A CA  1 
ATOM   263  C C   . GLU A 1 50  ? 105.200 109.866 94.111  1.00 45.30  ? 50  GLU A C   1 
ATOM   264  O O   . GLU A 1 50  ? 104.961 108.653 94.122  1.00 45.30  ? 50  GLU A O   1 
ATOM   265  C CB  . GLU A 1 50  ? 105.268 109.811 91.607  1.00 45.30  ? 50  GLU A CB  1 
ATOM   266  N N   . SER A 1 51  ? 105.663 110.512 95.180  1.00 34.74  ? 51  SER A N   1 
ATOM   267  C CA  . SER A 1 51  ? 105.927 109.831 96.439  1.00 34.74  ? 51  SER A CA  1 
ATOM   268  C C   . SER A 1 51  ? 104.714 109.779 97.359  1.00 34.74  ? 51  SER A C   1 
ATOM   269  O O   . SER A 1 51  ? 104.778 109.119 98.401  1.00 34.74  ? 51  SER A O   1 
ATOM   270  C CB  . SER A 1 51  ? 107.082 110.518 97.173  1.00 34.74  ? 51  SER A CB  1 
ATOM   271  O OG  . SER A 1 51  ? 106.869 111.914 97.268  1.00 34.74  ? 51  SER A OG  1 
ATOM   272  N N   . GLY A 1 52  ? 103.620 110.447 97.005  1.00 36.09  ? 52  GLY A N   1 
ATOM   273  C CA  . GLY A 1 52  ? 102.428 110.430 97.826  1.00 36.09  ? 52  GLY A CA  1 
ATOM   274  C C   . GLY A 1 52  ? 102.416 111.417 98.971  1.00 36.09  ? 52  GLY A C   1 
ATOM   275  O O   . GLY A 1 52  ? 101.573 111.291 99.865  1.00 36.09  ? 52  GLY A O   1 
ATOM   276  N N   . LYS A 1 53  ? 103.323 112.396 98.979  1.00 32.50  ? 53  LYS A N   1 
ATOM   277  C CA  . LYS A 1 53  ? 103.374 113.347 100.084 1.00 32.50  ? 53  LYS A CA  1 
ATOM   278  C C   . LYS A 1 53  ? 102.090 114.165 100.168 1.00 32.50  ? 53  LYS A C   1 
ATOM   279  O O   . LYS A 1 53  ? 101.580 114.431 101.263 1.00 32.50  ? 53  LYS A O   1 
ATOM   280  C CB  . LYS A 1 53  ? 104.589 114.262 99.927  1.00 32.50  ? 53  LYS A CB  1 
ATOM   281  C CG  . LYS A 1 53  ? 104.483 115.251 98.782  1.00 32.50  ? 53  LYS A CG  1 
ATOM   282  C CD  . LYS A 1 53  ? 105.744 116.083 98.649  1.00 32.50  ? 53  LYS A CD  1 
ATOM   283  C CE  . LYS A 1 53  ? 105.426 117.534 98.330  1.00 32.50  ? 53  LYS A CE  1 
ATOM   284  N NZ  . LYS A 1 53  ? 106.615 118.415 98.480  1.00 32.50  ? 53  LYS A NZ  1 
ATOM   285  N N   . ASN A 1 54  ? 101.555 114.577 99.017  1.00 48.59  ? 54  ASN A N   1 
ATOM   286  C CA  . ASN A 1 54  ? 100.368 115.424 99.019  1.00 48.59  ? 54  ASN A CA  1 
ATOM   287  C C   . ASN A 1 54  ? 99.203  114.749 99.723  1.00 48.59  ? 54  ASN A C   1 
ATOM   288  O O   . ASN A 1 54  ? 98.403  115.422 100.382 1.00 48.59  ? 54  ASN A O   1 
ATOM   289  C CB  . ASN A 1 54  ? 99.988  115.790 97.587  1.00 48.59  ? 54  ASN A CB  1 
ATOM   290  C CG  . ASN A 1 54  ? 101.000 116.710 96.938  1.00 48.59  ? 54  ASN A CG  1 
ATOM   291  O OD1 . ASN A 1 54  ? 101.708 117.450 97.619  1.00 48.59  ? 54  ASN A OD1 1 
ATOM   292  N ND2 . ASN A 1 54  ? 101.084 116.658 95.616  1.00 48.59  ? 54  ASN A ND2 1 
ATOM   293  N N   . THR A 1 55  ? 99.085  113.427 99.599  1.00 47.78  ? 55  THR A N   1 
ATOM   294  C CA  . THR A 1 55  ? 98.057  112.718 100.353 1.00 47.78  ? 55  THR A CA  1 
ATOM   295  C C   . THR A 1 55  ? 98.265  112.899 101.851 1.00 47.78  ? 55  THR A C   1 
ATOM   296  O O   . THR A 1 55  ? 97.305  113.126 102.592 1.00 47.78  ? 55  THR A O   1 
ATOM   297  C CB  . THR A 1 55  ? 98.060  111.234 99.989  1.00 47.78  ? 55  THR A CB  1 
ATOM   298  O OG1 . THR A 1 55  ? 99.324  110.656 100.336 1.00 47.78  ? 55  THR A OG1 1 
ATOM   299  C CG2 . THR A 1 55  ? 97.822  111.042 98.492  1.00 47.78  ? 55  THR A CG2 1 
ATOM   300  N N   . ILE A 1 56  ? 99.515  112.811 102.313 1.00 37.88  ? 56  ILE A N   1 
ATOM   301  C CA  . ILE A 1 56  ? 99.805  113.000 103.735 1.00 37.88  ? 56  ILE A CA  1 
ATOM   302  C C   . ILE A 1 56  ? 99.436  114.414 104.165 1.00 37.88  ? 56  ILE A C   1 
ATOM   303  O O   . ILE A 1 56  ? 98.867  114.629 105.247 1.00 37.88  ? 56  ILE A O   1 
ATOM   304  C CB  . ILE A 1 56  ? 101.290 112.707 104.021 1.00 37.88  ? 56  ILE A CB  1 
ATOM   305  C CG1 . ILE A 1 56  ? 101.675 111.305 103.548 1.00 37.88  ? 56  ILE A CG1 1 
ATOM   306  C CG2 . ILE A 1 56  ? 101.586 112.852 105.511 1.00 37.88  ? 56  ILE A CG2 1 
ATOM   307  C CD1 . ILE A 1 56  ? 103.172 111.112 103.397 1.00 37.88  ? 56  ILE A CD1 1 
ATOM   308  N N   . VAL A 1 57  ? 99.782  115.403 103.338 1.00 41.31  ? 57  VAL A N   1 
ATOM   309  C CA  . VAL A 1 57  ? 99.498  116.794 103.679 1.00 41.31  ? 57  VAL A CA  1 
ATOM   310  C C   . VAL A 1 57  ? 97.996  117.016 103.781 1.00 41.31  ? 57  VAL A C   1 
ATOM   311  O O   . VAL A 1 57  ? 97.510  117.655 104.720 1.00 41.31  ? 57  VAL A O   1 
ATOM   312  C CB  . VAL A 1 57  ? 100.138 117.740 102.645 1.00 41.31  ? 57  VAL A CB  1 
ATOM   313  C CG1 . VAL A 1 57  ? 99.873  119.195 103.007 1.00 41.31  ? 57  VAL A CG1 1 
ATOM   314  C CG2 . VAL A 1 57  ? 101.628 117.481 102.546 1.00 41.31  ? 57  VAL A CG2 1 
ATOM   315  N N   . LYS A 1 58  ? 97.237  116.493 102.817 1.00 54.89  ? 58  LYS A N   1 
ATOM   316  C CA  . LYS A 1 58  ? 95.786  116.607 102.882 1.00 54.89  ? 58  LYS A CA  1 
ATOM   317  C C   . LYS A 1 58  ? 95.240  115.885 104.107 1.00 54.89  ? 58  LYS A C   1 
ATOM   318  O O   . LYS A 1 58  ? 94.300  116.363 104.751 1.00 54.89  ? 58  LYS A O   1 
ATOM   319  C CB  . LYS A 1 58  ? 95.156  116.051 101.606 1.00 54.89  ? 58  LYS A CB  1 
ATOM   320  C CG  . LYS A 1 58  ? 95.431  114.577 101.377 1.00 54.89  ? 58  LYS A CG  1 
ATOM   321  C CD  . LYS A 1 58  ? 94.780  114.085 100.097 1.00 54.89  ? 58  LYS A CD  1 
ATOM   322  C CE  . LYS A 1 58  ? 95.433  114.695 98.869  1.00 54.89  ? 58  LYS A CE  1 
ATOM   323  N NZ  . LYS A 1 58  ? 94.803  114.220 97.607  1.00 54.89  ? 58  LYS A NZ  1 
ATOM   324  N N   . GLN A 1 59  ? 95.811  114.725 104.436 1.00 50.72  ? 59  GLN A N   1 
ATOM   325  C CA  . GLN A 1 59  ? 95.373  113.984 105.612 1.00 50.72  ? 59  GLN A CA  1 
ATOM   326  C C   . GLN A 1 59  ? 95.506  114.830 106.870 1.00 50.72  ? 59  GLN A C   1 
ATOM   327  O O   . GLN A 1 59  ? 94.553  114.968 107.646 1.00 50.72  ? 59  GLN A O   1 
ATOM   328  C CB  . GLN A 1 59  ? 96.189  112.699 105.748 1.00 50.72  ? 59  GLN A CB  1 
ATOM   329  C CG  . GLN A 1 59  ? 95.752  111.809 106.895 1.00 50.72  ? 59  GLN A CG  1 
ATOM   330  C CD  . GLN A 1 59  ? 96.543  110.520 106.965 1.00 50.72  ? 59  GLN A CD  1 
ATOM   331  O OE1 . GLN A 1 59  ? 97.459  110.293 106.173 1.00 50.72  ? 59  GLN A OE1 1 
ATOM   332  N NE2 . GLN A 1 59  ? 96.191  109.664 107.916 1.00 50.72  ? 59  GLN A NE2 1 
ATOM   333  N N   . MET A 1 60  ? 96.688  115.405 107.092 1.00 46.16  ? 60  MET A N   1 
ATOM   334  C CA  . MET A 1 60  ? 96.872  116.241 108.277 1.00 46.16  ? 60  MET A CA  1 
ATOM   335  C C   . MET A 1 60  ? 95.997  117.489 108.224 1.00 46.16  ? 60  MET A C   1 
ATOM   336  O O   . MET A 1 60  ? 95.449  117.909 109.249 1.00 46.16  ? 60  MET A O   1 
ATOM   337  C CB  . MET A 1 60  ? 98.343  116.611 108.458 1.00 46.16  ? 60  MET A CB  1 
ATOM   338  C CG  . MET A 1 60  ? 99.287  115.422 108.422 1.00 46.16  ? 60  MET A CG  1 
ATOM   339  S SD  . MET A 1 60  ? 101.022 115.899 108.506 1.00 46.16  ? 60  MET A SD  1 
ATOM   340  C CE  . MET A 1 60  ? 101.800 114.286 108.546 1.00 46.16  ? 60  MET A CE  1 
ATOM   341  N N   . ARG A 1 61  ? 95.849  118.098 107.046 1.00 57.26  ? 61  ARG A N   1 
ATOM   342  C CA  . ARG A 1 61  ? 95.034  119.305 106.951 1.00 57.26  ? 61  ARG A CA  1 
ATOM   343  C C   . ARG A 1 61  ? 93.589  119.025 107.349 1.00 57.26  ? 61  ARG A C   1 
ATOM   344  O O   . ARG A 1 61  ? 92.998  119.767 108.141 1.00 57.26  ? 61  ARG A O   1 
ATOM   345  C CB  . ARG A 1 61  ? 95.101  119.877 105.534 1.00 57.26  ? 61  ARG A CB  1 
ATOM   346  C CG  . ARG A 1 61  ? 95.048  121.397 105.488 1.00 57.26  ? 61  ARG A CG  1 
ATOM   347  C CD  . ARG A 1 61  ? 94.632  121.901 104.115 1.00 57.26  ? 61  ARG A CD  1 
ATOM   348  N NE  . ARG A 1 61  ? 95.719  121.857 103.144 1.00 57.26  ? 61  ARG A NE  1 
ATOM   349  C CZ  . ARG A 1 61  ? 96.778  122.655 103.164 1.00 57.26  ? 61  ARG A CZ  1 
ATOM   350  N NH1 . ARG A 1 61  ? 96.929  123.580 104.099 1.00 57.26  ? 61  ARG A NH1 1 
ATOM   351  N NH2 . ARG A 1 61  ? 97.705  122.529 102.219 1.00 57.26  ? 61  ARG A NH2 1 
ATOM   352  N N   . THR A 1 204 ? 100.602 128.342 91.528  1.00 46.35  ? 204 THR A N   1 
ATOM   353  C CA  . THR A 1 204 ? 101.000 129.745 91.537  1.00 46.35  ? 204 THR A CA  1 
ATOM   354  C C   . THR A 1 204 ? 101.800 130.097 92.786  1.00 46.35  ? 204 THR A C   1 
ATOM   355  O O   . THR A 1 204 ? 102.852 130.737 92.693  1.00 46.35  ? 204 THR A O   1 
ATOM   356  C CB  . THR A 1 204 ? 99.762  130.641 91.437  1.00 46.35  ? 204 THR A CB  1 
ATOM   357  O OG1 . THR A 1 204 ? 98.905  130.404 92.561  1.00 46.35  ? 204 THR A OG1 1 
ATOM   358  C CG2 . THR A 1 204 ? 99.000  130.357 90.151  1.00 46.35  ? 204 THR A CG2 1 
ATOM   359  N N   . SER A 1 205 ? 101.318 129.686 93.955  1.00 29.98  ? 205 SER A N   1 
ATOM   360  C CA  . SER A 1 205 ? 102.018 129.980 95.197  1.00 29.98  ? 205 SER A CA  1 
ATOM   361  C C   . SER A 1 205 ? 103.348 129.241 95.242  1.00 29.98  ? 205 SER A C   1 
ATOM   362  O O   . SER A 1 205 ? 103.440 128.069 94.870  1.00 29.98  ? 205 SER A O   1 
ATOM   363  C CB  . SER A 1 205 ? 101.156 129.588 96.395  1.00 29.98  ? 205 SER A CB  1 
ATOM   364  O OG  . SER A 1 205 ? 101.822 129.868 97.612  1.00 29.98  ? 205 SER A OG  1 
ATOM   365  N N   . GLY A 1 206 ? 104.386 129.937 95.701  1.00 21.26  ? 206 GLY A N   1 
ATOM   366  C CA  . GLY A 1 206 ? 105.713 129.356 95.759  1.00 21.26  ? 206 GLY A CA  1 
ATOM   367  C C   . GLY A 1 206 ? 105.985 128.493 96.968  1.00 21.26  ? 206 GLY A C   1 
ATOM   368  O O   . GLY A 1 206 ? 107.021 127.824 97.009  1.00 21.26  ? 206 GLY A O   1 
ATOM   369  N N   . ILE A 1 207 ? 105.087 128.492 97.952  1.00 19.78  ? 207 ILE A N   1 
ATOM   370  C CA  . ILE A 1 207 ? 105.248 127.667 99.143  1.00 19.78  ? 207 ILE A CA  1 
ATOM   371  C C   . ILE A 1 207 ? 103.905 127.608 99.849  1.00 19.78  ? 207 ILE A C   1 
ATOM   372  O O   . ILE A 1 207 ? 103.084 128.518 99.723  1.00 19.78  ? 207 ILE A O   1 
ATOM   373  C CB  . ILE A 1 207 ? 106.364 128.222 100.064 1.00 19.78  ? 207 ILE A CB  1 
ATOM   374  C CG1 . ILE A 1 207 ? 106.939 127.106 100.937 1.00 19.78  ? 207 ILE A CG1 1 
ATOM   375  C CG2 . ILE A 1 207 ? 105.831 129.351 100.927 1.00 19.78  ? 207 ILE A CG2 1 
ATOM   376  C CD1 . ILE A 1 207 ? 108.315 127.406 101.472 1.00 19.78  ? 207 ILE A CD1 1 
ATOM   377  N N   . PHE A 1 208 ? 103.684 126.531 100.596 1.00 26.10  ? 208 PHE A N   1 
ATOM   378  C CA  . PHE A 1 208 ? 102.421 126.285 101.271 1.00 26.10  ? 208 PHE A CA  1 
ATOM   379  C C   . PHE A 1 208 ? 102.659 126.072 102.760 1.00 26.10  ? 208 PHE A C   1 
ATOM   380  O O   . PHE A 1 208 ? 103.766 125.743 103.192 1.00 26.10  ? 208 PHE A O   1 
ATOM   381  C CB  . PHE A 1 208 ? 101.704 125.069 100.676 1.00 26.10  ? 208 PHE A CB  1 
ATOM   382  C CG  . PHE A 1 208 ? 101.413 125.198 99.209  1.00 26.10  ? 208 PHE A CG  1 
ATOM   383  C CD1 . PHE A 1 208 ? 102.421 125.049 98.274  1.00 26.10  ? 208 PHE A CD1 1 
ATOM   384  C CD2 . PHE A 1 208 ? 100.133 125.473 98.768  1.00 26.10  ? 208 PHE A CD2 1 
ATOM   385  C CE1 . PHE A 1 208 ? 102.156 125.169 96.927  1.00 26.10  ? 208 PHE A CE1 1 
ATOM   386  C CE2 . PHE A 1 208 ? 99.863  125.595 97.421  1.00 26.10  ? 208 PHE A CE2 1 
ATOM   387  C CZ  . PHE A 1 208 ? 100.875 125.444 96.500  1.00 26.10  ? 208 PHE A CZ  1 
ATOM   388  N N   . GLU A 1 209 ? 101.602 126.268 103.541 1.00 26.60  ? 209 GLU A N   1 
ATOM   389  C CA  . GLU A 1 209 ? 101.672 126.203 104.992 1.00 26.60  ? 209 GLU A CA  1 
ATOM   390  C C   . GLU A 1 209 ? 100.693 125.166 105.519 1.00 26.60  ? 209 GLU A C   1 
ATOM   391  O O   . GLU A 1 209 ? 99.597  124.990 104.976 1.00 26.60  ? 209 GLU A O   1 
ATOM   392  C CB  . GLU A 1 209 ? 101.358 127.562 105.618 1.00 26.60  ? 209 GLU A CB  1 
ATOM   393  C CG  . GLU A 1 209 ? 102.342 128.652 105.247 1.00 26.60  ? 209 GLU A CG  1 
ATOM   394  C CD  . GLU A 1 209 ? 103.690 128.460 105.898 1.00 26.60  ? 209 GLU A CD  1 
ATOM   395  O OE1 . GLU A 1 209 ? 103.742 127.811 106.963 1.00 26.60  ? 209 GLU A OE1 1 
ATOM   396  O OE2 . GLU A 1 209 ? 104.693 128.963 105.351 1.00 26.60  ? 209 GLU A OE2 1 
ATOM   397  N N   . THR A 1 210 ? 101.096 124.481 106.588 1.00 30.56  ? 210 THR A N   1 
ATOM   398  C CA  . THR A 1 210 ? 100.241 123.484 107.230 1.00 30.56  ? 210 THR A CA  1 
ATOM   399  C C   . THR A 1 210 ? 100.579 123.492 108.718 1.00 30.56  ? 210 THR A C   1 
ATOM   400  O O   . THR A 1 210 ? 101.540 122.843 109.141 1.00 30.56  ? 210 THR A O   1 
ATOM   401  C CB  . THR A 1 210 ? 100.443 122.104 106.621 1.00 30.56  ? 210 THR A CB  1 
ATOM   402  O OG1 . THR A 1 210 ? 100.034 122.121 105.248 1.00 30.56  ? 210 THR A OG1 1 
ATOM   403  C CG2 . THR A 1 210 ? 99.631  121.061 107.373 1.00 30.56  ? 210 THR A CG2 1 
ATOM   404  N N   . LYS A 1 211 ? 99.787  124.222 109.499 1.00 26.56  ? 211 LYS A N   1 
ATOM   405  C CA  . LYS A 1 211 ? 100.002 124.354 110.933 1.00 26.56  ? 211 LYS A CA  1 
ATOM   406  C C   . LYS A 1 211 ? 99.035  123.440 111.671 1.00 26.56  ? 211 LYS A C   1 
ATOM   407  O O   . LYS A 1 211 ? 97.816  123.543 111.489 1.00 26.56  ? 211 LYS A O   1 
ATOM   408  C CB  . LYS A 1 211 ? 99.815  125.803 111.380 1.00 26.56  ? 211 LYS A CB  1 
ATOM   409  C CG  . LYS A 1 211 ? 100.608 126.801 110.559 1.00 26.56  ? 211 LYS A CG  1 
ATOM   410  C CD  . LYS A 1 211 ? 100.503 128.215 111.114 1.00 26.56  ? 211 LYS A CD  1 
ATOM   411  C CE  . LYS A 1 211 ? 101.052 128.323 112.531 1.00 26.56  ? 211 LYS A CE  1 
ATOM   412  N NZ  . LYS A 1 211 ? 102.327 127.576 112.714 1.00 26.56  ? 211 LYS A NZ  1 
ATOM   413  N N   . PHE A 1 212 ? 99.577  122.550 112.497 1.00 33.43  ? 212 PHE A N   1 
ATOM   414  C CA  . PHE A 1 212 ? 98.775  121.656 113.317 1.00 33.43  ? 212 PHE A CA  1 
ATOM   415  C C   . PHE A 1 212 ? 99.416  121.549 114.691 1.00 33.43  ? 212 PHE A C   1 
ATOM   416  O O   . PHE A 1 212 ? 100.582 121.904 114.883 1.00 33.43  ? 212 PHE A O   1 
ATOM   417  C CB  . PHE A 1 212 ? 98.628  120.266 112.676 1.00 33.43  ? 212 PHE A CB  1 
ATOM   418  C CG  . PHE A 1 212 ? 99.932  119.548 112.468 1.00 33.43  ? 212 PHE A CG  1 
ATOM   419  C CD1 . PHE A 1 212 ? 100.798 119.931 111.461 1.00 33.43  ? 212 PHE A CD1 1 
ATOM   420  C CD2 . PHE A 1 212 ? 100.284 118.478 113.270 1.00 33.43  ? 212 PHE A CD2 1 
ATOM   421  C CE1 . PHE A 1 212 ? 101.993 119.267 111.266 1.00 33.43  ? 212 PHE A CE1 1 
ATOM   422  C CE2 . PHE A 1 212 ? 101.477 117.812 113.078 1.00 33.43  ? 212 PHE A CE2 1 
ATOM   423  C CZ  . PHE A 1 212 ? 102.332 118.207 112.075 1.00 33.43  ? 212 PHE A CZ  1 
ATOM   424  N N   . GLN A 1 213 ? 98.634  121.069 115.655 1.00 39.38  ? 213 GLN A N   1 
ATOM   425  C CA  . GLN A 1 213 ? 99.084  120.950 117.034 1.00 39.38  ? 213 GLN A CA  1 
ATOM   426  C C   . GLN A 1 213 ? 98.870  119.529 117.531 1.00 39.38  ? 213 GLN A C   1 
ATOM   427  O O   . GLN A 1 213 ? 97.826  118.922 117.275 1.00 39.38  ? 213 GLN A O   1 
ATOM   428  C CB  . GLN A 1 213 ? 98.347  121.940 117.945 1.00 39.38  ? 213 GLN A CB  1 
ATOM   429  C CG  . GLN A 1 213 ? 96.975  121.472 118.410 1.00 39.38  ? 213 GLN A CG  1 
ATOM   430  C CD  . GLN A 1 213 ? 96.230  122.541 119.182 1.00 39.38  ? 213 GLN A CD  1 
ATOM   431  O OE1 . GLN A 1 213 ? 96.833  123.472 119.718 1.00 39.38  ? 213 GLN A OE1 1 
ATOM   432  N NE2 . GLN A 1 213 ? 94.909  122.413 119.247 1.00 39.38  ? 213 GLN A NE2 1 
ATOM   433  N N   . VAL A 1 214 ? 99.867  119.006 118.241 1.00 35.30  ? 214 VAL A N   1 
ATOM   434  C CA  . VAL A 1 214 ? 99.799  117.694 118.870 1.00 35.30  ? 214 VAL A CA  1 
ATOM   435  C C   . VAL A 1 214 ? 100.210 117.849 120.327 1.00 35.30  ? 214 VAL A C   1 
ATOM   436  O O   . VAL A 1 214 ? 101.230 118.480 120.623 1.00 35.30  ? 214 VAL A O   1 
ATOM   437  C CB  . VAL A 1 214 ? 100.702 116.671 118.156 1.00 35.30  ? 214 VAL A CB  1 
ATOM   438  C CG1 . VAL A 1 214 ? 100.805 115.391 118.966 1.00 35.30  ? 214 VAL A CG1 1 
ATOM   439  C CG2 . VAL A 1 214 ? 100.170 116.382 116.769 1.00 35.30  ? 214 VAL A CG2 1 
ATOM   440  N N   . ASP A 1 215 ? 99.414  117.282 121.234 1.00 38.55  ? 215 ASP A N   1 
ATOM   441  C CA  . ASP A 1 215 ? 99.693  117.364 122.667 1.00 38.55  ? 215 ASP A CA  1 
ATOM   442  C C   . ASP A 1 215 ? 99.894  118.815 123.094 1.00 38.55  ? 215 ASP A C   1 
ATOM   443  O O   . ASP A 1 215 ? 100.779 119.137 123.890 1.00 38.55  ? 215 ASP A O   1 
ATOM   444  C CB  . ASP A 1 215 ? 100.913 116.518 123.035 1.00 38.55  ? 215 ASP A CB  1 
ATOM   445  C CG  . ASP A 1 215 ? 100.654 115.031 122.903 1.00 38.55  ? 215 ASP A CG  1 
ATOM   446  O OD1 . ASP A 1 215 ? 99.492  114.608 123.073 1.00 38.55  ? 215 ASP A OD1 1 
ATOM   447  O OD2 . ASP A 1 215 ? 101.615 114.281 122.629 1.00 38.55  ? 215 ASP A OD2 1 
ATOM   448  N N   . LYS A 1 216 ? 99.064  119.704 122.554 1.00 38.71  ? 216 LYS A N   1 
ATOM   449  C CA  . LYS A 1 216 ? 99.151  121.138 122.815 1.00 38.71  ? 216 LYS A CA  1 
ATOM   450  C C   . LYS A 1 216 ? 100.495 121.717 122.394 1.00 38.71  ? 216 LYS A C   1 
ATOM   451  O O   . LYS A 1 216 ? 100.886 122.789 122.867 1.00 38.71  ? 216 LYS A O   1 
ATOM   452  C CB  . LYS A 1 216 ? 98.886  121.446 124.292 1.00 38.71  ? 216 LYS A CB  1 
ATOM   453  N N   . VAL A 1 217 ? 101.213 121.025 121.514 1.00 32.53  ? 217 VAL A N   1 
ATOM   454  C CA  . VAL A 1 217 ? 102.463 121.508 120.941 1.00 32.53  ? 217 VAL A CA  1 
ATOM   455  C C   . VAL A 1 217 ? 102.202 121.833 119.480 1.00 32.53  ? 217 VAL A C   1 
ATOM   456  O O   . VAL A 1 217 ? 101.662 121.001 118.741 1.00 32.53  ? 217 VAL A O   1 
ATOM   457  C CB  . VAL A 1 217 ? 103.590 120.470 121.082 1.00 32.53  ? 217 VAL A CB  1 
ATOM   458  C CG1 . VAL A 1 217 ? 104.921 121.072 120.665 1.00 32.53  ? 217 VAL A CG1 1 
ATOM   459  C CG2 . VAL A 1 217 ? 103.656 119.952 122.507 1.00 32.53  ? 217 VAL A CG2 1 
ATOM   460  N N   . ASN A 1 218 ? 102.581 123.036 119.062 1.00 28.09  ? 218 ASN A N   1 
ATOM   461  C CA  . ASN A 1 218 ? 102.269 123.530 117.730 1.00 28.09  ? 218 ASN A CA  1 
ATOM   462  C C   . ASN A 1 218 ? 103.435 123.259 116.789 1.00 28.09  ? 218 ASN A C   1 
ATOM   463  O O   . ASN A 1 218 ? 104.583 123.592 117.102 1.00 28.09  ? 218 ASN A O   1 
ATOM   464  C CB  . ASN A 1 218 ? 101.960 125.026 117.766 1.00 28.09  ? 218 ASN A CB  1 
ATOM   465  C CG  . ASN A 1 218 ? 100.689 125.339 118.529 1.00 28.09  ? 218 ASN A CG  1 
ATOM   466  O OD1 . ASN A 1 218 ? 99.593  124.962 118.115 1.00 28.09  ? 218 ASN A OD1 1 
ATOM   467  N ND2 . ASN A 1 218 ? 100.829 126.037 119.649 1.00 28.09  ? 218 ASN A ND2 1 
ATOM   468  N N   . PHE A 1 219 ? 103.135 122.657 115.643 1.00 25.71  ? 219 PHE A N   1 
ATOM   469  C CA  . PHE A 1 219 ? 104.102 122.407 114.584 1.00 25.71  ? 219 PHE A CA  1 
ATOM   470  C C   . PHE A 1 219 ? 103.792 123.313 113.399 1.00 25.71  ? 219 PHE A C   1 
ATOM   471  O O   . PHE A 1 219 ? 102.752 123.973 113.344 1.00 25.71  ? 219 PHE A O   1 
ATOM   472  C CB  . PHE A 1 219 ? 104.082 120.935 114.171 1.00 25.71  ? 219 PHE A CB  1 
ATOM   473  C CG  . PHE A 1 219 ? 104.542 120.001 115.247 1.00 25.71  ? 219 PHE A CG  1 
ATOM   474  C CD1 . PHE A 1 219 ? 105.883 119.698 115.387 1.00 25.71  ? 219 PHE A CD1 1 
ATOM   475  C CD2 . PHE A 1 219 ? 103.637 119.427 116.120 1.00 25.71  ? 219 PHE A CD2 1 
ATOM   476  C CE1 . PHE A 1 219 ? 106.313 118.840 116.375 1.00 25.71  ? 219 PHE A CE1 1 
ATOM   477  C CE2 . PHE A 1 219 ? 104.062 118.570 117.110 1.00 25.71  ? 219 PHE A CE2 1 
ATOM   478  C CZ  . PHE A 1 219 ? 105.403 118.277 117.237 1.00 25.71  ? 219 PHE A CZ  1 
ATOM   479  N N   . HIS A 1 220 ? 104.706 123.336 112.435 1.00 23.02  ? 220 HIS A N   1 
ATOM   480  C CA  . HIS A 1 220 ? 104.599 124.275 111.324 1.00 23.02  ? 220 HIS A CA  1 
ATOM   481  C C   . HIS A 1 220 ? 105.351 123.673 110.146 1.00 23.02  ? 220 HIS A C   1 
ATOM   482  O O   . HIS A 1 220 ? 106.584 123.718 110.114 1.00 23.02  ? 220 HIS A O   1 
ATOM   483  C CB  . HIS A 1 220 ? 105.166 125.632 111.735 1.00 23.02  ? 220 HIS A CB  1 
ATOM   484  C CG  . HIS A 1 220 ? 104.890 126.734 110.763 1.00 23.02  ? 220 HIS A CG  1 
ATOM   485  N ND1 . HIS A 1 220 ? 105.511 127.962 110.843 1.00 23.02  ? 220 HIS A ND1 1 
ATOM   486  C CD2 . HIS A 1 220 ? 104.052 126.803 109.704 1.00 23.02  ? 220 HIS A CD2 1 
ATOM   487  C CE1 . HIS A 1 220 ? 105.065 128.740 109.873 1.00 23.02  ? 220 HIS A CE1 1 
ATOM   488  N NE2 . HIS A 1 220 ? 104.182 128.060 109.165 1.00 23.02  ? 220 HIS A NE2 1 
ATOM   489  N N   . MET A 1 221 ? 104.618 123.114 109.185 1.00 24.01  ? 221 MET A N   1 
ATOM   490  C CA  . MET A 1 221 ? 105.197 122.341 108.092 1.00 24.01  ? 221 MET A CA  1 
ATOM   491  C C   . MET A 1 221 ? 105.100 123.117 106.787 1.00 24.01  ? 221 MET A C   1 
ATOM   492  O O   . MET A 1 221 ? 104.073 123.739 106.505 1.00 24.01  ? 221 MET A O   1 
ATOM   493  C CB  . MET A 1 221 ? 104.490 120.994 107.938 1.00 24.01  ? 221 MET A CB  1 
ATOM   494  C CG  . MET A 1 221 ? 105.076 120.139 106.831 1.00 24.01  ? 221 MET A CG  1 
ATOM   495  S SD  . MET A 1 221 ? 104.802 118.372 107.039 1.00 24.01  ? 221 MET A SD  1 
ATOM   496  C CE  . MET A 1 221 ? 103.015 118.309 107.121 1.00 24.01  ? 221 MET A CE  1 
ATOM   497  N N   . PHE A 1 222 ? 106.165 123.067 105.993 1.00 19.36  ? 222 PHE A N   1 
ATOM   498  C CA  . PHE A 1 222 ? 106.271 123.821 104.751 1.00 19.36  ? 222 PHE A CA  1 
ATOM   499  C C   . PHE A 1 222 ? 106.419 122.863 103.578 1.00 19.36  ? 222 PHE A C   1 
ATOM   500  O O   . PHE A 1 222 ? 107.363 122.067 103.537 1.00 19.36  ? 222 PHE A O   1 
ATOM   501  C CB  . PHE A 1 222 ? 107.454 124.781 104.815 1.00 19.36  ? 222 PHE A CB  1 
ATOM   502  C CG  . PHE A 1 222 ? 107.476 125.608 106.057 1.00 19.36  ? 222 PHE A CG  1 
ATOM   503  C CD1 . PHE A 1 222 ? 106.606 126.666 106.212 1.00 19.36  ? 222 PHE A CD1 1 
ATOM   504  C CD2 . PHE A 1 222 ? 108.346 125.309 107.085 1.00 19.36  ? 222 PHE A CD2 1 
ATOM   505  C CE1 . PHE A 1 222 ? 106.620 127.424 107.358 1.00 19.36  ? 222 PHE A CE1 1 
ATOM   506  C CE2 . PHE A 1 222 ? 108.358 126.061 108.238 1.00 19.36  ? 222 PHE A CE2 1 
ATOM   507  C CZ  . PHE A 1 222 ? 107.496 127.120 108.372 1.00 19.36  ? 222 PHE A CZ  1 
ATOM   508  N N   . ASP A 1 223 ? 105.498 122.957 102.625 1.00 22.05  ? 223 ASP A N   1 
ATOM   509  C CA  . ASP A 1 223 ? 105.520 122.154 101.410 1.00 22.05  ? 223 ASP A CA  1 
ATOM   510  C C   . ASP A 1 223 ? 106.027 123.012 100.260 1.00 22.05  ? 223 ASP A C   1 
ATOM   511  O O   . ASP A 1 223 ? 105.441 124.054 99.955  1.00 22.05  ? 223 ASP A O   1 
ATOM   512  C CB  . ASP A 1 223 ? 104.126 121.612 101.099 1.00 22.05  ? 223 ASP A CB  1 
ATOM   513  C CG  . ASP A 1 223 ? 104.130 120.611 99.965  1.00 22.05  ? 223 ASP A CG  1 
ATOM   514  O OD1 . ASP A 1 223 ? 105.211 120.358 99.396  1.00 22.05  ? 223 ASP A OD1 1 
ATOM   515  O OD2 . ASP A 1 223 ? 103.045 120.085 99.634  1.00 22.05  ? 223 ASP A OD2 1 
ATOM   516  N N   . VAL A 1 224 ? 107.112 122.573 99.620  1.00 21.10  ? 224 VAL A N   1 
ATOM   517  C CA  . VAL A 1 224 ? 107.644 123.315 98.487  1.00 21.10  ? 224 VAL A CA  1 
ATOM   518  C C   . VAL A 1 224 ? 106.647 123.260 97.333  1.00 21.10  ? 224 VAL A C   1 
ATOM   519  O O   . VAL A 1 224 ? 105.803 122.360 97.250  1.00 21.10  ? 224 VAL A O   1 
ATOM   520  C CB  . VAL A 1 224 ? 109.011 122.755 98.060  1.00 21.10  ? 224 VAL A CB  1 
ATOM   521  C CG1 . VAL A 1 224 ? 109.606 123.595 96.947  1.00 21.10  ? 224 VAL A CG1 1 
ATOM   522  C CG2 . VAL A 1 224 ? 109.953 122.701 99.249  1.00 21.10  ? 224 VAL A CG2 1 
ATOM   523  N N   . GLY A 1 225 ? 106.740 124.239 96.439  1.00 22.97  ? 225 GLY A N   1 
ATOM   524  C CA  . GLY A 1 225 ? 105.866 124.289 95.286  1.00 22.97  ? 225 GLY A CA  1 
ATOM   525  C C   . GLY A 1 225 ? 106.241 125.390 94.319  1.00 22.97  ? 225 GLY A C   1 
ATOM   526  O O   . GLY A 1 225 ? 106.757 126.434 94.725  1.00 22.97  ? 225 GLY A O   1 
ATOM   527  N N   . ALA A 1 226 ? 105.940 125.198 93.033  1.00 27.97  ? 226 ALA A N   1 
ATOM   528  C CA  . ALA A 1 226 ? 106.200 126.211 91.985  1.00 27.97  ? 226 ALA A CA  1 
ATOM   529  C C   . ALA A 1 226 ? 107.679 126.597 91.987  1.00 27.97  ? 226 ALA A C   1 
ATOM   530  O O   . ALA A 1 226 ? 107.964 127.801 91.857  1.00 27.97  ? 226 ALA A O   1 
ATOM   531  C CB  . ALA A 1 226 ? 105.317 127.411 92.211  1.00 27.97  ? 226 ALA A CB  1 
ATOM   532  N N   . GLN A 1 227 ? 108.581 125.624 92.127  1.00 17.81  ? 227 GLN A N   1 
ATOM   533  C CA  . GLN A 1 227 ? 110.046 125.873 92.096  1.00 17.81  ? 227 GLN A CA  1 
ATOM   534  C C   . GLN A 1 227 ? 110.707 124.859 91.162  1.00 17.81  ? 227 GLN A C   1 
ATOM   535  O O   . GLN A 1 227 ? 110.115 123.784 90.960  1.00 17.81  ? 227 GLN A O   1 
ATOM   536  C CB  . GLN A 1 227 ? 110.636 125.792 93.505  1.00 17.81  ? 227 GLN A CB  1 
ATOM   537  C CG  . GLN A 1 227 ? 110.178 126.914 94.425  1.00 17.81  ? 227 GLN A CG  1 
ATOM   538  C CD  . GLN A 1 227 ? 110.890 128.216 94.153  1.00 17.81  ? 227 GLN A CD  1 
ATOM   539  O OE1 . GLN A 1 227 ? 111.676 128.335 93.216  1.00 17.81  ? 227 GLN A OE1 1 
ATOM   540  N NE2 . GLN A 1 227 ? 110.614 129.212 94.979  1.00 17.81  ? 227 GLN A NE2 1 
ATOM   541  N N   . ARG A 1 228 ? 111.881 125.179 90.618  1.00 17.90  ? 228 ARG A N   1 
ATOM   542  C CA  . ARG A 1 228 ? 112.616 124.313 89.714  1.00 17.90  ? 228 ARG A CA  1 
ATOM   543  C C   . ARG A 1 228 ? 113.248 123.159 90.489  1.00 17.90  ? 228 ARG A C   1 
ATOM   544  O O   . ARG A 1 228 ? 113.145 123.065 91.714  1.00 17.90  ? 228 ARG A O   1 
ATOM   545  C CB  . ARG A 1 228 ? 113.682 125.106 88.961  1.00 17.90  ? 228 ARG A CB  1 
ATOM   546  C CG  . ARG A 1 228 ? 113.113 126.107 87.974  1.00 17.90  ? 228 ARG A CG  1 
ATOM   547  C CD  . ARG A 1 228 ? 114.132 126.484 86.918  1.00 17.90  ? 228 ARG A CD  1 
ATOM   548  N NE  . ARG A 1 228 ? 115.465 126.659 87.484  1.00 17.90  ? 228 ARG A NE  1 
ATOM   549  C CZ  . ARG A 1 228 ? 116.594 126.557 86.796  1.00 17.90  ? 228 ARG A CZ  1 
ATOM   550  N NH1 . ARG A 1 228 ? 116.594 126.287 85.502  1.00 17.90  ? 228 ARG A NH1 1 
ATOM   551  N NH2 . ARG A 1 228 ? 117.752 126.731 87.423  1.00 17.90  ? 228 ARG A NH2 1 
ATOM   552  N N   . ASP A 1 229 ? 113.908 122.267 89.754  1.00 21.73  ? 229 ASP A N   1 
ATOM   553  C CA  . ASP A 1 229 ? 114.474 121.059 90.335  1.00 21.73  ? 229 ASP A CA  1 
ATOM   554  C C   . ASP A 1 229 ? 115.927 121.218 90.762  1.00 21.73  ? 229 ASP A C   1 
ATOM   555  O O   . ASP A 1 229 ? 116.513 120.254 91.263  1.00 21.73  ? 229 ASP A O   1 
ATOM   556  C CB  . ASP A 1 229 ? 114.368 119.900 89.341  1.00 21.73  ? 229 ASP A CB  1 
ATOM   557  C CG  . ASP A 1 229 ? 115.105 120.173 88.048  1.00 21.73  ? 229 ASP A CG  1 
ATOM   558  O OD1 . ASP A 1 229 ? 115.218 121.357 87.669  1.00 21.73  ? 229 ASP A OD1 1 
ATOM   559  O OD2 . ASP A 1 229 ? 115.566 119.205 87.410  1.00 21.73  ? 229 ASP A OD2 1 
ATOM   560  N N   . GLU A 1 230 ? 116.524 122.396 90.578  1.00 19.73  ? 230 GLU A N   1 
ATOM   561  C CA  . GLU A 1 230 ? 117.898 122.643 91.013  1.00 19.73  ? 230 GLU A CA  1 
ATOM   562  C C   . GLU A 1 230 ? 117.855 123.165 92.446  1.00 19.73  ? 230 GLU A C   1 
ATOM   563  O O   . GLU A 1 230 ? 117.719 124.362 92.711  1.00 19.73  ? 230 GLU A O   1 
ATOM   564  C CB  . GLU A 1 230 ? 118.591 123.612 90.066  1.00 19.73  ? 230 GLU A CB  1 
ATOM   565  C CG  . GLU A 1 230 ? 118.436 123.233 88.601  1.00 19.73  ? 230 GLU A CG  1 
ATOM   566  C CD  . GLU A 1 230 ? 119.573 123.744 87.735  1.00 19.73  ? 230 GLU A CD  1 
ATOM   567  O OE1 . GLU A 1 230 ? 119.653 124.970 87.512  1.00 19.73  ? 230 GLU A OE1 1 
ATOM   568  O OE2 . GLU A 1 230 ? 120.385 122.917 87.271  1.00 19.73  ? 230 GLU A OE2 1 
ATOM   569  N N   . ARG A 1 231 ? 117.982 122.230 93.391  1.00 14.64  ? 231 ARG A N   1 
ATOM   570  C CA  . ARG A 1 231 ? 117.725 122.531 94.795  1.00 14.64  ? 231 ARG A CA  1 
ATOM   571  C C   . ARG A 1 231 ? 118.944 123.075 95.524  1.00 14.64  ? 231 ARG A C   1 
ATOM   572  O O   . ARG A 1 231 ? 118.814 123.512 96.670  1.00 14.64  ? 231 ARG A O   1 
ATOM   573  C CB  . ARG A 1 231 ? 117.254 121.271 95.516  1.00 14.64  ? 231 ARG A CB  1 
ATOM   574  C CG  . ARG A 1 231 ? 116.053 120.596 94.893  1.00 14.64  ? 231 ARG A CG  1 
ATOM   575  C CD  . ARG A 1 231 ? 115.622 119.404 95.725  1.00 14.64  ? 231 ARG A CD  1 
ATOM   576  N NE  . ARG A 1 231 ? 114.434 118.749 95.191  1.00 14.64  ? 231 ARG A NE  1 
ATOM   577  C CZ  . ARG A 1 231 ? 114.450 117.841 94.225  1.00 14.64  ? 231 ARG A CZ  1 
ATOM   578  N NH1 . ARG A 1 231 ? 115.579 117.455 93.654  1.00 14.64  ? 231 ARG A NH1 1 
ATOM   579  N NH2 . ARG A 1 231 ? 113.302 117.305 93.823  1.00 14.64  ? 231 ARG A NH2 1 
ATOM   580  N N   . ARG A 1 232 ? 120.121 123.066 94.899  1.00 12.50  ? 232 ARG A N   1 
ATOM   581  C CA  . ARG A 1 232 ? 121.350 123.292 95.650  1.00 12.50  ? 232 ARG A CA  1 
ATOM   582  C C   . ARG A 1 232 ? 121.499 124.719 96.157  1.00 12.50  ? 232 ARG A C   1 
ATOM   583  O O   . ARG A 1 232 ? 122.530 125.029 96.764  1.00 12.50  ? 232 ARG A O   1 
ATOM   584  C CB  . ARG A 1 232 ? 122.563 122.921 94.793  1.00 12.50  ? 232 ARG A CB  1 
ATOM   585  C CG  . ARG A 1 232 ? 122.980 123.967 93.782  1.00 12.50  ? 232 ARG A CG  1 
ATOM   586  C CD  . ARG A 1 232 ? 124.107 123.443 92.919  1.00 12.50  ? 232 ARG A CD  1 
ATOM   587  N NE  . ARG A 1 232 ? 124.518 124.397 91.896  1.00 12.50  ? 232 ARG A NE  1 
ATOM   588  C CZ  . ARG A 1 232 ? 123.998 124.466 90.679  1.00 12.50  ? 232 ARG A CZ  1 
ATOM   589  N NH1 . ARG A 1 232 ? 123.011 123.670 90.301  1.00 12.50  ? 232 ARG A NH1 1 
ATOM   590  N NH2 . ARG A 1 232 ? 124.480 125.356 89.819  1.00 12.50  ? 232 ARG A NH2 1 
ATOM   591  N N   . LYS A 1 233 ? 120.519 125.593 95.935  1.00 13.51  ? 233 LYS A N   1 
ATOM   592  C CA  . LYS A 1 233 ? 120.591 126.971 96.402  1.00 13.51  ? 233 LYS A CA  1 
ATOM   593  C C   . LYS A 1 233 ? 119.483 127.330 97.379  1.00 13.51  ? 233 LYS A C   1 
ATOM   594  O O   . LYS A 1 233 ? 119.758 127.918 98.429  1.00 13.51  ? 233 LYS A O   1 
ATOM   595  C CB  . LYS A 1 233 ? 120.562 127.928 95.205  1.00 13.51  ? 233 LYS A CB  1 
ATOM   596  C CG  . LYS A 1 233 ? 121.830 127.892 94.371  1.00 13.51  ? 233 LYS A CG  1 
ATOM   597  C CD  . LYS A 1 233 ? 123.042 128.297 95.190  1.00 13.51  ? 233 LYS A CD  1 
ATOM   598  C CE  . LYS A 1 233 ? 124.206 128.701 94.307  1.00 13.51  ? 233 LYS A CE  1 
ATOM   599  N NZ  . LYS A 1 233 ? 125.399 129.088 95.108  1.00 13.51  ? 233 LYS A NZ  1 
ATOM   600  N N   . TRP A 1 234 ? 118.230 127.003 97.069  1.00 13.82  ? 234 TRP A N   1 
ATOM   601  C CA  . TRP A 1 234 ? 117.150 127.296 98.000  1.00 13.82  ? 234 TRP A CA  1 
ATOM   602  C C   . TRP A 1 234 ? 117.022 126.250 99.096  1.00 13.82  ? 234 TRP A C   1 
ATOM   603  O O   . TRP A 1 234 ? 116.214 126.435 100.011 1.00 13.82  ? 234 TRP A O   1 
ATOM   604  C CB  . TRP A 1 234 ? 115.821 127.435 97.253  1.00 13.82  ? 234 TRP A CB  1 
ATOM   605  C CG  . TRP A 1 234 ? 115.336 126.195 96.574  1.00 13.82  ? 234 TRP A CG  1 
ATOM   606  C CD1 . TRP A 1 234 ? 115.428 125.905 95.247  1.00 13.82  ? 234 TRP A CD1 1 
ATOM   607  C CD2 . TRP A 1 234 ? 114.654 125.092 97.179  1.00 13.82  ? 234 TRP A CD2 1 
ATOM   608  N NE1 . TRP A 1 234 ? 114.858 124.686 94.988  1.00 13.82  ? 234 TRP A NE1 1 
ATOM   609  C CE2 . TRP A 1 234 ? 114.374 124.165 96.159  1.00 13.82  ? 234 TRP A CE2 1 
ATOM   610  C CE3 . TRP A 1 234 ? 114.258 124.793 98.485  1.00 13.82  ? 234 TRP A CE3 1 
ATOM   611  C CZ2 . TRP A 1 234 ? 113.722 122.962 96.403  1.00 13.82  ? 234 TRP A CZ2 1 
ATOM   612  C CZ3 . TRP A 1 234 ? 113.609 123.599 98.725  1.00 13.82  ? 234 TRP A CZ3 1 
ATOM   613  C CH2 . TRP A 1 234 ? 113.347 122.699 97.690  1.00 13.82  ? 234 TRP A CH2 1 
ATOM   614  N N   . ILE A 1 235 ? 117.792 125.164 99.031  1.00 15.06  ? 235 ILE A N   1 
ATOM   615  C CA  . ILE A 1 235 ? 117.752 124.166 100.095 1.00 15.06  ? 235 ILE A CA  1 
ATOM   616  C C   . ILE A 1 235 ? 118.379 124.711 101.370 1.00 15.06  ? 235 ILE A C   1 
ATOM   617  O O   . ILE A 1 235 ? 117.935 124.384 102.476 1.00 15.06  ? 235 ILE A O   1 
ATOM   618  C CB  . ILE A 1 235 ? 118.449 122.873 99.636  1.00 15.06  ? 235 ILE A CB  1 
ATOM   619  C CG1 . ILE A 1 235 ? 118.135 121.720 100.591 1.00 15.06  ? 235 ILE A CG1 1 
ATOM   620  C CG2 . ILE A 1 235 ? 119.948 123.079 99.548  1.00 15.06  ? 235 ILE A CG2 1 
ATOM   621  C CD1 . ILE A 1 235 ? 116.687 121.303 100.596 1.00 15.06  ? 235 ILE A CD1 1 
ATOM   622  N N   . GLN A 1 236 ? 119.413 125.545 101.244 1.00 14.43  ? 236 GLN A N   1 
ATOM   623  C CA  . GLN A 1 236 ? 120.151 125.997 102.420 1.00 14.43  ? 236 GLN A CA  1 
ATOM   624  C C   . GLN A 1 236 ? 119.278 126.801 103.371 1.00 14.43  ? 236 GLN A C   1 
ATOM   625  O O   . GLN A 1 236 ? 119.625 126.954 104.546 1.00 14.43  ? 236 GLN A O   1 
ATOM   626  C CB  . GLN A 1 236 ? 121.353 126.832 101.987 1.00 14.43  ? 236 GLN A CB  1 
ATOM   627  C CG  . GLN A 1 236 ? 122.344 126.082 101.124 1.00 14.43  ? 236 GLN A CG  1 
ATOM   628  C CD  . GLN A 1 236 ? 123.246 127.007 100.340 1.00 14.43  ? 236 GLN A CD  1 
ATOM   629  O OE1 . GLN A 1 236 ? 123.219 128.222 100.526 1.00 14.43  ? 236 GLN A OE1 1 
ATOM   630  N NE2 . GLN A 1 236 ? 124.053 126.436 99.455  1.00 14.43  ? 236 GLN A NE2 1 
ATOM   631  N N   . CYS A 1 237 ? 118.150 127.327 102.891 1.00 16.43  ? 237 CYS A N   1 
ATOM   632  C CA  . CYS A 1 237 ? 117.296 128.134 103.755 1.00 16.43  ? 237 CYS A CA  1 
ATOM   633  C C   . CYS A 1 237 ? 116.785 127.339 104.947 1.00 16.43  ? 237 CYS A C   1 
ATOM   634  O O   . CYS A 1 237 ? 116.447 127.923 105.981 1.00 16.43  ? 237 CYS A O   1 
ATOM   635  C CB  . CYS A 1 237 ? 116.121 128.695 102.958 1.00 16.43  ? 237 CYS A CB  1 
ATOM   636  S SG  . CYS A 1 237 ? 116.586 129.904 101.707 1.00 16.43  ? 237 CYS A SG  1 
ATOM   637  N N   . PHE A 1 238 ? 116.723 126.014 104.829 1.00 15.62  ? 238 PHE A N   1 
ATOM   638  C CA  . PHE A 1 238 ? 116.147 125.156 105.857 1.00 15.62  ? 238 PHE A CA  1 
ATOM   639  C C   . PHE A 1 238 ? 117.208 124.488 106.723 1.00 15.62  ? 238 PHE A C   1 
ATOM   640  O O   . PHE A 1 238 ? 117.029 123.342 107.143 1.00 15.62  ? 238 PHE A O   1 
ATOM   641  C CB  . PHE A 1 238 ? 115.252 124.100 105.214 1.00 15.62  ? 238 PHE A CB  1 
ATOM   642  C CG  . PHE A 1 238 ? 114.147 124.671 104.380 1.00 15.62  ? 238 PHE A CG  1 
ATOM   643  C CD1 . PHE A 1 238 ? 114.354 124.977 103.050 1.00 15.62  ? 238 PHE A CD1 1 
ATOM   644  C CD2 . PHE A 1 238 ? 112.900 124.903 104.927 1.00 15.62  ? 238 PHE A CD2 1 
ATOM   645  C CE1 . PHE A 1 238 ? 113.339 125.502 102.283 1.00 15.62  ? 238 PHE A CE1 1 
ATOM   646  C CE2 . PHE A 1 238 ? 111.884 125.426 104.163 1.00 15.62  ? 238 PHE A CE2 1 
ATOM   647  C CZ  . PHE A 1 238 ? 112.104 125.727 102.840 1.00 15.62  ? 238 PHE A CZ  1 
ATOM   648  N N   . ASN A 1 239 ? 118.311 125.179 107.001 1.00 15.98  ? 239 ASN A N   1 
ATOM   649  C CA  . ASN A 1 239 ? 119.362 124.602 107.828 1.00 15.98  ? 239 ASN A CA  1 
ATOM   650  C C   . ASN A 1 239 ? 119.064 124.696 109.316 1.00 15.98  ? 239 ASN A C   1 
ATOM   651  O O   . ASN A 1 239 ? 119.832 124.148 110.115 1.00 15.98  ? 239 ASN A O   1 
ATOM   652  C CB  . ASN A 1 239 ? 120.696 125.287 107.540 1.00 15.98  ? 239 ASN A CB  1 
ATOM   653  C CG  . ASN A 1 239 ? 120.889 126.544 108.357 1.00 15.98  ? 239 ASN A CG  1 
ATOM   654  O OD1 . ASN A 1 239 ? 119.939 127.276 108.623 1.00 15.98  ? 239 ASN A OD1 1 
ATOM   655  N ND2 . ASN A 1 239 ? 122.124 126.799 108.767 1.00 15.98  ? 239 ASN A ND2 1 
ATOM   656  N N   . ASP A 1 240 ? 117.986 125.371 109.707 1.00 16.02  ? 240 ASP A N   1 
ATOM   657  C CA  . ASP A 1 240 ? 117.634 125.545 111.109 1.00 16.02  ? 240 ASP A CA  1 
ATOM   658  C C   . ASP A 1 240 ? 116.317 124.880 111.479 1.00 16.02  ? 240 ASP A C   1 
ATOM   659  O O   . ASP A 1 240 ? 115.838 125.070 112.601 1.00 16.02  ? 240 ASP A O   1 
ATOM   660  C CB  . ASP A 1 240 ? 117.568 127.037 111.451 1.00 16.02  ? 240 ASP A CB  1 
ATOM   661  C CG  . ASP A 1 240 ? 116.636 127.805 110.535 1.00 16.02  ? 240 ASP A CG  1 
ATOM   662  O OD1 . ASP A 1 240 ? 115.635 127.220 110.072 1.00 16.02  ? 240 ASP A OD1 1 
ATOM   663  O OD2 . ASP A 1 240 ? 116.907 128.997 110.273 1.00 16.02  ? 240 ASP A OD2 1 
ATOM   664  N N   . VAL A 1 241 ? 115.716 124.114 110.571 1.00 16.18  ? 241 VAL A N   1 
ATOM   665  C CA  . VAL A 1 241 ? 114.467 123.434 110.882 1.00 16.18  ? 241 VAL A CA  1 
ATOM   666  C C   . VAL A 1 241 ? 114.718 122.350 111.922 1.00 16.18  ? 241 VAL A C   1 
ATOM   667  O O   . VAL A 1 241 ? 115.841 121.857 112.086 1.00 16.18  ? 241 VAL A O   1 
ATOM   668  C CB  . VAL A 1 241 ? 113.842 122.839 109.608 1.00 16.18  ? 241 VAL A CB  1 
ATOM   669  C CG1 . VAL A 1 241 ? 113.568 123.933 108.596 1.00 16.18  ? 241 VAL A CG1 1 
ATOM   670  C CG2 . VAL A 1 241 ? 114.750 121.772 109.014 1.00 16.18  ? 241 VAL A CG2 1 
ATOM   671  N N   . THR A 1 242 ? 113.657 121.975 112.638 1.00 15.84  ? 242 THR A N   1 
ATOM   672  C CA  . THR A 1 242 ? 113.773 120.897 113.613 1.00 15.84  ? 242 THR A CA  1 
ATOM   673  C C   . THR A 1 242 ? 114.221 119.604 112.941 1.00 15.84  ? 242 THR A C   1 
ATOM   674  O O   . THR A 1 242 ? 115.141 118.930 113.414 1.00 15.84  ? 242 THR A O   1 
ATOM   675  C CB  . THR A 1 242 ? 112.437 120.693 114.328 1.00 15.84  ? 242 THR A CB  1 
ATOM   676  O OG1 . THR A 1 242 ? 111.874 121.967 114.662 1.00 15.84  ? 242 THR A OG1 1 
ATOM   677  C CG2 . THR A 1 242 ? 112.623 119.884 115.598 1.00 15.84  ? 242 THR A CG2 1 
ATOM   678  N N   . ALA A 1 243 ? 113.581 119.248 111.830 1.00 15.17  ? 243 ALA A N   1 
ATOM   679  C CA  . ALA A 1 243 ? 113.923 118.040 111.097 1.00 15.17  ? 243 ALA A CA  1 
ATOM   680  C C   . ALA A 1 243 ? 113.337 118.140 109.698 1.00 15.17  ? 243 ALA A C   1 
ATOM   681  O O   . ALA A 1 243 ? 112.423 118.926 109.444 1.00 15.17  ? 243 ALA A O   1 
ATOM   682  C CB  . ALA A 1 243 ? 113.407 116.787 111.808 1.00 15.17  ? 243 ALA A CB  1 
ATOM   683  N N   . ILE A 1 244 ? 113.874 117.324 108.795 1.00 14.16  ? 244 ILE A N   1 
ATOM   684  C CA  . ILE A 1 244 ? 113.430 117.268 107.407 1.00 14.16  ? 244 ILE A CA  1 
ATOM   685  C C   . ILE A 1 244 ? 112.776 115.915 107.177 1.00 14.16  ? 244 ILE A C   1 
ATOM   686  O O   . ILE A 1 244 ? 113.363 114.873 107.488 1.00 14.16  ? 244 ILE A O   1 
ATOM   687  C CB  . ILE A 1 244 ? 114.594 117.482 106.428 1.00 14.16  ? 244 ILE A CB  1 
ATOM   688  C CG1 . ILE A 1 244 ? 115.158 118.893 106.571 1.00 14.16  ? 244 ILE A CG1 1 
ATOM   689  C CG2 . ILE A 1 244 ? 114.136 117.237 105.003 1.00 14.16  ? 244 ILE A CG2 1 
ATOM   690  C CD1 . ILE A 1 244 ? 116.525 119.066 105.948 1.00 14.16  ? 244 ILE A CD1 1 
ATOM   691  N N   . ILE A 1 245 ? 111.565 115.929 106.634 1.00 15.10  ? 245 ILE A N   1 
ATOM   692  C CA  . ILE A 1 245 ? 110.877 114.706 106.242 1.00 15.10  ? 245 ILE A CA  1 
ATOM   693  C C   . ILE A 1 245 ? 111.247 114.393 104.800 1.00 15.10  ? 245 ILE A C   1 
ATOM   694  O O   . ILE A 1 245 ? 111.206 115.274 103.933 1.00 15.10  ? 245 ILE A O   1 
ATOM   695  C CB  . ILE A 1 245 ? 109.355 114.849 106.408 1.00 15.10  ? 245 ILE A CB  1 
ATOM   696  C CG1 . ILE A 1 245 ? 109.030 115.336 107.818 1.00 15.10  ? 245 ILE A CG1 1 
ATOM   697  C CG2 . ILE A 1 245 ? 108.663 113.527 106.134 1.00 15.10  ? 245 ILE A CG2 1 
ATOM   698  C CD1 . ILE A 1 245 ? 107.556 115.423 108.108 1.00 15.10  ? 245 ILE A CD1 1 
ATOM   699  N N   . PHE A 1 246 ? 111.622 113.142 104.542 1.00 14.45  ? 246 PHE A N   1 
ATOM   700  C CA  . PHE A 1 246 ? 112.076 112.700 103.225 1.00 14.45  ? 246 PHE A CA  1 
ATOM   701  C C   . PHE A 1 246 ? 111.235 111.499 102.811 1.00 14.45  ? 246 PHE A C   1 
ATOM   702  O O   . PHE A 1 246 ? 111.598 110.351 103.065 1.00 14.45  ? 246 PHE A O   1 
ATOM   703  C CB  . PHE A 1 246 ? 113.557 112.365 103.258 1.00 14.45  ? 246 PHE A CB  1 
ATOM   704  C CG  . PHE A 1 246 ? 114.186 112.267 101.899 1.00 14.45  ? 246 PHE A CG  1 
ATOM   705  C CD1 . PHE A 1 246 ? 114.737 113.381 101.294 1.00 14.45  ? 246 PHE A CD1 1 
ATOM   706  C CD2 . PHE A 1 246 ? 114.229 111.059 101.228 1.00 14.45  ? 246 PHE A CD2 1 
ATOM   707  C CE1 . PHE A 1 246 ? 115.313 113.291 100.047 1.00 14.45  ? 246 PHE A CE1 1 
ATOM   708  C CE2 . PHE A 1 246 ? 114.805 110.968 99.981  1.00 14.45  ? 246 PHE A CE2 1 
ATOM   709  C CZ  . PHE A 1 246 ? 115.346 112.083 99.392  1.00 14.45  ? 246 PHE A CZ  1 
ATOM   710  N N   . VAL A 1 247 ? 110.103 111.771 102.166 1.00 19.49  ? 247 VAL A N   1 
ATOM   711  C CA  . VAL A 1 247 ? 109.233 110.701 101.691 1.00 19.49  ? 247 VAL A CA  1 
ATOM   712  C C   . VAL A 1 247 ? 109.865 110.072 100.458 1.00 19.49  ? 247 VAL A C   1 
ATOM   713  O O   . VAL A 1 247 ? 110.269 110.771 99.522  1.00 19.49  ? 247 VAL A O   1 
ATOM   714  C CB  . VAL A 1 247 ? 107.828 111.232 101.386 1.00 19.49  ? 247 VAL A CB  1 
ATOM   715  C CG1 . VAL A 1 247 ? 106.882 110.083 101.065 1.00 19.49  ? 247 VAL A CG1 1 
ATOM   716  C CG2 . VAL A 1 247 ? 107.309 112.050 102.555 1.00 19.49  ? 247 VAL A CG2 1 
ATOM   717  N N   . VAL A 1 248 ? 109.955 108.747 100.451 1.00 21.64  ? 248 VAL A N   1 
ATOM   718  C CA  . VAL A 1 248 ? 110.562 108.005 99.355  1.00 21.64  ? 248 VAL A CA  1 
ATOM   719  C C   . VAL A 1 248 ? 109.506 107.106 98.732  1.00 21.64  ? 248 VAL A C   1 
ATOM   720  O O   . VAL A 1 248 ? 108.516 106.734 99.374  1.00 21.64  ? 248 VAL A O   1 
ATOM   721  C CB  . VAL A 1 248 ? 111.774 107.181 99.835  1.00 21.64  ? 248 VAL A CB  1 
ATOM   722  C CG1 . VAL A 1 248 ? 112.320 106.309 98.715  1.00 21.64  ? 248 VAL A CG1 1 
ATOM   723  C CG2 . VAL A 1 248 ? 112.853 108.099 100.372 1.00 21.64  ? 248 VAL A CG2 1 
ATOM   724  N N   . ALA A 1 249 ? 109.718 106.765 97.461  1.00 28.41  ? 249 ALA A N   1 
ATOM   725  C CA  . ALA A 1 249 ? 108.853 105.835 96.742  1.00 28.41  ? 249 ALA A CA  1 
ATOM   726  C C   . ALA A 1 249 ? 109.580 104.496 96.658  1.00 28.41  ? 249 ALA A C   1 
ATOM   727  O O   . ALA A 1 249 ? 110.261 104.180 95.683  1.00 28.41  ? 249 ALA A O   1 
ATOM   728  C CB  . ALA A 1 249 ? 108.498 106.385 95.367  1.00 28.41  ? 249 ALA A CB  1 
ATOM   729  N N   . SER A 1 250 ? 109.421 103.697 97.713  1.00 29.35  ? 250 SER A N   1 
ATOM   730  C CA  . SER A 1 250 ? 110.121 102.420 97.792  1.00 29.35  ? 250 SER A CA  1 
ATOM   731  C C   . SER A 1 250 ? 109.695 101.481 96.673  1.00 29.35  ? 250 SER A C   1 
ATOM   732  O O   . SER A 1 250 ? 110.528 100.775 96.095  1.00 29.35  ? 250 SER A O   1 
ATOM   733  C CB  . SER A 1 250 ? 109.870 101.771 99.150  1.00 29.35  ? 250 SER A CB  1 
ATOM   734  O OG  . SER A 1 250 ? 108.702 100.973 99.113  1.00 29.35  ? 250 SER A OG  1 
ATOM   735  N N   . SER A 1 251 ? 108.402 101.450 96.359  1.00 36.69  ? 251 SER A N   1 
ATOM   736  C CA  . SER A 1 251 ? 107.892 100.555 95.329  1.00 36.69  ? 251 SER A CA  1 
ATOM   737  C C   . SER A 1 251 ? 108.137 101.074 93.918  1.00 36.69  ? 251 SER A C   1 
ATOM   738  O O   . SER A 1 251 ? 107.850 100.357 92.954  1.00 36.69  ? 251 SER A O   1 
ATOM   739  C CB  . SER A 1 251 ? 106.394 100.324 95.526  1.00 36.69  ? 251 SER A CB  1 
ATOM   740  O OG  . SER A 1 251 ? 105.659 101.485 95.192  1.00 36.69  ? 251 SER A OG  1 
ATOM   741  N N   . SER A 1 252 ? 108.660 102.293 93.772  1.00 34.65  ? 252 SER A N   1 
ATOM   742  C CA  . SER A 1 252 ? 108.897 102.868 92.455  1.00 34.65  ? 252 SER A CA  1 
ATOM   743  C C   . SER A 1 252 ? 110.030 102.187 91.700  1.00 34.65  ? 252 SER A C   1 
ATOM   744  O O   . SER A 1 252 ? 110.197 102.454 90.506  1.00 34.65  ? 252 SER A O   1 
ATOM   745  C CB  . SER A 1 252 ? 109.202 104.359 92.587  1.00 34.65  ? 252 SER A CB  1 
ATOM   746  O OG  . SER A 1 252 ? 110.389 104.572 93.330  1.00 34.65  ? 252 SER A OG  1 
ATOM   747  N N   . TYR A 1 253 ? 110.813 101.334 92.360  1.00 40.68  ? 253 TYR A N   1 
ATOM   748  C CA  . TYR A 1 253 ? 111.877 100.608 91.679  1.00 40.68  ? 253 TYR A CA  1 
ATOM   749  C C   . TYR A 1 253 ? 111.336 99.929  90.428  1.00 40.68  ? 253 TYR A C   1 
ATOM   750  O O   . TYR A 1 253 ? 110.153 99.590  90.341  1.00 40.68  ? 253 TYR A O   1 
ATOM   751  C CB  . TYR A 1 253 ? 112.489 99.560  92.610  1.00 40.68  ? 253 TYR A CB  1 
ATOM   752  C CG  . TYR A 1 253 ? 111.537 98.437  92.959  1.00 40.68  ? 253 TYR A CG  1 
ATOM   753  C CD1 . TYR A 1 253 ? 110.458 98.653  93.804  1.00 40.68  ? 253 TYR A CD1 1 
ATOM   754  C CD2 . TYR A 1 253 ? 111.711 97.163  92.437  1.00 40.68  ? 253 TYR A CD2 1 
ATOM   755  C CE1 . TYR A 1 253 ? 109.584 97.635  94.121  1.00 40.68  ? 253 TYR A CE1 1 
ATOM   756  C CE2 . TYR A 1 253 ? 110.839 96.137  92.750  1.00 40.68  ? 253 TYR A CE2 1 
ATOM   757  C CZ  . TYR A 1 253 ? 109.778 96.381  93.594  1.00 40.68  ? 253 TYR A CZ  1 
ATOM   758  O OH  . TYR A 1 253 ? 108.901 95.372  93.916  1.00 40.68  ? 253 TYR A OH  1 
ATOM   759  N N   . ASN A 1 254 ? 112.214 99.733  89.451  1.00 44.80  ? 254 ASN A N   1 
ATOM   760  C CA  . ASN A 1 254 ? 111.836 99.078  88.205  1.00 44.80  ? 254 ASN A CA  1 
ATOM   761  C C   . ASN A 1 254 ? 110.828 99.920  87.434  1.00 44.80  ? 254 ASN A C   1 
ATOM   762  O O   . ASN A 1 254 ? 111.127 100.427 86.354  1.00 44.80  ? 254 ASN A O   1 
ATOM   763  C CB  . ASN A 1 254 ? 111.258 97.689  88.486  1.00 44.80  ? 254 ASN A CB  1 
ATOM   764  C CG  . ASN A 1 254 ? 111.320 96.777  87.278  1.00 44.80  ? 254 ASN A CG  1 
ATOM   765  O OD1 . ASN A 1 254 ? 111.297 97.237  86.137  1.00 44.80  ? 254 ASN A OD1 1 
ATOM   766  N ND2 . ASN A 1 254 ? 111.402 95.474  87.523  1.00 44.80  ? 254 ASN A ND2 1 
ATOM   767  N N   . GLN A 1 262 ? 111.531 107.872 84.020  1.00 32.01  ? 262 GLN A N   1 
ATOM   768  C CA  . GLN A 1 262 ? 112.856 107.456 84.464  1.00 32.01  ? 262 GLN A CA  1 
ATOM   769  C C   . GLN A 1 262 ? 112.760 106.014 84.957  1.00 32.01  ? 262 GLN A C   1 
ATOM   770  O O   . GLN A 1 262 ? 111.741 105.614 85.517  1.00 32.01  ? 262 GLN A O   1 
ATOM   771  C CB  . GLN A 1 262 ? 113.370 108.390 85.563  1.00 32.01  ? 262 GLN A CB  1 
ATOM   772  N N   . THR A 1 263 ? 113.821 105.232 84.748  1.00 37.56  ? 263 THR A N   1 
ATOM   773  C CA  . THR A 1 263 ? 113.749 103.801 85.020  1.00 37.56  ? 263 THR A CA  1 
ATOM   774  C C   . THR A 1 263 ? 113.980 103.484 86.496  1.00 37.56  ? 263 THR A C   1 
ATOM   775  O O   . THR A 1 263 ? 113.254 102.674 87.083  1.00 37.56  ? 263 THR A O   1 
ATOM   776  C CB  . THR A 1 263 ? 114.757 103.052 84.141  1.00 37.56  ? 263 THR A CB  1 
ATOM   777  N N   . ASN A 1 264 ? 114.978 104.111 87.115  1.00 30.43  ? 264 ASN A N   1 
ATOM   778  C CA  . ASN A 1 264 ? 115.406 103.785 88.476  1.00 30.43  ? 264 ASN A CA  1 
ATOM   779  C C   . ASN A 1 264 ? 115.116 104.976 89.383  1.00 30.43  ? 264 ASN A C   1 
ATOM   780  O O   . ASN A 1 264 ? 115.969 105.841 89.588  1.00 30.43  ? 264 ASN A O   1 
ATOM   781  C CB  . ASN A 1 264 ? 116.895 103.411 88.480  1.00 30.43  ? 264 ASN A CB  1 
ATOM   782  C CG  . ASN A 1 264 ? 117.324 102.731 89.761  1.00 30.43  ? 264 ASN A CG  1 
ATOM   783  O OD1 . ASN A 1 264 ? 116.866 103.081 90.849  1.00 30.43  ? 264 ASN A OD1 1 
ATOM   784  N ND2 . ASN A 1 264 ? 118.212 101.750 89.641  1.00 30.43  ? 264 ASN A ND2 1 
ATOM   785  N N   . ARG A 1 265 ? 113.899 105.018 89.929  1.00 30.86  ? 265 ARG A N   1 
ATOM   786  C CA  . ARG A 1 265 ? 113.550 106.079 90.870  1.00 30.86  ? 265 ARG A CA  1 
ATOM   787  C C   . ARG A 1 265 ? 114.279 105.898 92.197  1.00 30.86  ? 265 ARG A C   1 
ATOM   788  O O   . ARG A 1 265 ? 114.702 106.880 92.823  1.00 30.86  ? 265 ARG A O   1 
ATOM   789  C CB  . ARG A 1 265 ? 112.040 106.102 91.090  1.00 30.86  ? 265 ARG A CB  1 
ATOM   790  N N   . LEU A 1 266 ? 114.431 104.651 92.641  1.00 26.75  ? 266 LEU A N   1 
ATOM   791  C CA  . LEU A 1 266 ? 115.074 104.393 93.923  1.00 26.75  ? 266 LEU A CA  1 
ATOM   792  C C   . LEU A 1 266 ? 116.498 104.924 93.935  1.00 26.75  ? 266 LEU A C   1 
ATOM   793  O O   . LEU A 1 266 ? 116.948 105.493 94.932  1.00 26.75  ? 266 LEU A O   1 
ATOM   794  C CB  . LEU A 1 266 ? 115.057 102.897 94.227  1.00 26.75  ? 266 LEU A CB  1 
ATOM   795  C CG  . LEU A 1 266 ? 113.855 102.397 95.022  1.00 26.75  ? 266 LEU A CG  1 
ATOM   796  C CD1 . LEU A 1 266 ? 113.971 102.816 96.476  1.00 26.75  ? 266 LEU A CD1 1 
ATOM   797  C CD2 . LEU A 1 266 ? 112.569 102.920 94.413  1.00 26.75  ? 266 LEU A CD2 1 
ATOM   798  N N   . GLN A 1 267 ? 117.231 104.733 92.836  1.00 19.55  ? 267 GLN A N   1 
ATOM   799  C CA  . GLN A 1 267 ? 118.589 105.261 92.765  1.00 19.55  ? 267 GLN A CA  1 
ATOM   800  C C   . GLN A 1 267 ? 118.589 106.784 92.831  1.00 19.55  ? 267 GLN A C   1 
ATOM   801  O O   . GLN A 1 267 ? 119.476 107.385 93.448  1.00 19.55  ? 267 GLN A O   1 
ATOM   802  C CB  . GLN A 1 267 ? 119.276 104.779 91.490  1.00 19.55  ? 267 GLN A CB  1 
ATOM   803  C CG  . GLN A 1 267 ? 120.756 105.113 91.423  1.00 19.55  ? 267 GLN A CG  1 
ATOM   804  C CD  . GLN A 1 267 ? 121.592 104.265 92.357  1.00 19.55  ? 267 GLN A CD  1 
ATOM   805  O OE1 . GLN A 1 267 ? 121.404 104.287 93.569  1.00 19.55  ? 267 GLN A OE1 1 
ATOM   806  N NE2 . GLN A 1 267 ? 122.526 103.514 91.792  1.00 19.55  ? 267 GLN A NE2 1 
ATOM   807  N N   . ALA A 1 268 ? 117.615 107.426 92.187  1.00 16.82  ? 268 ALA A N   1 
ATOM   808  C CA  . ALA A 1 268 ? 117.515 108.878 92.272  1.00 16.82  ? 268 ALA A CA  1 
ATOM   809  C C   . ALA A 1 268 ? 117.322 109.324 93.714  1.00 16.82  ? 268 ALA A C   1 
ATOM   810  O O   . ALA A 1 268 ? 117.994 110.250 94.189  1.00 16.82  ? 268 ALA A O   1 
ATOM   811  C CB  . ALA A 1 268 ? 116.363 109.372 91.397  1.00 16.82  ? 268 ALA A CB  1 
ATOM   812  N N   . ALA A 1 269 ? 116.408 108.668 94.432  1.00 17.21  ? 269 ALA A N   1 
ATOM   813  C CA  . ALA A 1 269 ? 116.189 109.016 95.832  1.00 17.21  ? 269 ALA A CA  1 
ATOM   814  C C   . ALA A 1 269 ? 117.438 108.752 96.661  1.00 17.21  ? 269 ALA A C   1 
ATOM   815  O O   . ALA A 1 269 ? 117.767 109.523 97.571  1.00 17.21  ? 269 ALA A O   1 
ATOM   816  C CB  . ALA A 1 269 ? 115.002 108.232 96.388  1.00 17.21  ? 269 ALA A CB  1 
ATOM   817  N N   . LEU A 1 270 ? 118.148 107.666 96.358  1.00 16.13  ? 270 LEU A N   1 
ATOM   818  C CA  . LEU A 1 270 ? 119.375 107.341 97.075  1.00 16.13  ? 270 LEU A CA  1 
ATOM   819  C C   . LEU A 1 270 ? 120.416 108.435 96.897  1.00 16.13  ? 270 LEU A C   1 
ATOM   820  O O   . LEU A 1 270 ? 121.034 108.888 97.868  1.00 16.13  ? 270 LEU A O   1 
ATOM   821  C CB  . LEU A 1 270 ? 119.912 106.001 96.574  1.00 16.13  ? 270 LEU A CB  1 
ATOM   822  C CG  . LEU A 1 270 ? 120.868 105.231 97.478  1.00 16.13  ? 270 LEU A CG  1 
ATOM   823  C CD1 . LEU A 1 270 ? 120.133 104.621 98.655  1.00 16.13  ? 270 LEU A CD1 1 
ATOM   824  C CD2 . LEU A 1 270 ? 121.574 104.151 96.679  1.00 16.13  ? 270 LEU A CD2 1 
ATOM   825  N N   . LYS A 1 271 ? 120.623 108.876 95.657  1.00 15.49  ? 271 LYS A N   1 
ATOM   826  C CA  . LYS A 1 271 ? 121.609 109.922 95.401  1.00 15.49  ? 271 LYS A CA  1 
ATOM   827  C C   . LYS A 1 271 ? 121.193 111.231 96.054  1.00 15.49  ? 271 LYS A C   1 
ATOM   828  O O   . LYS A 1 271 ? 122.032 111.964 96.588  1.00 15.49  ? 271 LYS A O   1 
ATOM   829  C CB  . LYS A 1 271 ? 121.810 110.110 93.898  1.00 15.49  ? 271 LYS A CB  1 
ATOM   830  C CG  . LYS A 1 271 ? 122.315 108.879 93.151  1.00 15.49  ? 271 LYS A CG  1 
ATOM   831  C CD  . LYS A 1 271 ? 123.503 108.220 93.833  1.00 15.49  ? 271 LYS A CD  1 
ATOM   832  C CE  . LYS A 1 271 ? 124.656 109.184 94.019  1.00 15.49  ? 271 LYS A CE  1 
ATOM   833  N NZ  . LYS A 1 271 ? 125.844 108.511 94.608  1.00 15.49  ? 271 LYS A NZ  1 
ATOM   834  N N   . LEU A 1 272 ? 119.899 111.551 96.019  1.00 13.04  ? 272 LEU A N   1 
ATOM   835  C CA  . LEU A 1 272 ? 119.439 112.783 96.652  1.00 13.04  ? 272 LEU A CA  1 
ATOM   836  C C   . LEU A 1 272 ? 119.687 112.753 98.156  1.00 13.04  ? 272 LEU A C   1 
ATOM   837  O O   . LEU A 1 272 ? 120.188 113.728 98.733  1.00 13.04  ? 272 LEU A O   1 
ATOM   838  C CB  . LEU A 1 272 ? 117.957 112.999 96.355  1.00 13.04  ? 272 LEU A CB  1 
ATOM   839  C CG  . LEU A 1 272 ? 117.347 114.287 96.907  1.00 13.04  ? 272 LEU A CG  1 
ATOM   840  C CD1 . LEU A 1 272 ? 118.056 115.504 96.340  1.00 13.04  ? 272 LEU A CD1 1 
ATOM   841  C CD2 . LEU A 1 272 ? 115.863 114.344 96.601  1.00 13.04  ? 272 LEU A CD2 1 
ATOM   842  N N   . PHE A 1 273 ? 119.348 111.640 98.809  1.00 13.95  ? 273 PHE A N   1 
ATOM   843  C CA  . PHE A 1 273 ? 119.575 111.529 100.245 1.00 13.95  ? 273 PHE A CA  1 
ATOM   844  C C   . PHE A 1 273 ? 121.061 111.598 100.565 1.00 13.95  ? 273 PHE A C   1 
ATOM   845  O O   . PHE A 1 273 ? 121.469 112.237 101.541 1.00 13.95  ? 273 PHE A O   1 
ATOM   846  C CB  . PHE A 1 273 ? 118.967 110.231 100.773 1.00 13.95  ? 273 PHE A CB  1 
ATOM   847  C CG  . PHE A 1 273 ? 119.443 109.858 102.144 1.00 13.95  ? 273 PHE A CG  1 
ATOM   848  C CD1 . PHE A 1 273 ? 119.156 110.659 103.232 1.00 13.95  ? 273 PHE A CD1 1 
ATOM   849  C CD2 . PHE A 1 273 ? 120.175 108.705 102.346 1.00 13.95  ? 273 PHE A CD2 1 
ATOM   850  C CE1 . PHE A 1 273 ? 119.594 110.317 104.494 1.00 13.95  ? 273 PHE A CE1 1 
ATOM   851  C CE2 . PHE A 1 273 ? 120.614 108.361 103.605 1.00 13.95  ? 273 PHE A CE2 1 
ATOM   852  C CZ  . PHE A 1 273 ? 120.323 109.169 104.680 1.00 13.95  ? 273 PHE A CZ  1 
ATOM   853  N N   . ASP A 1 274 ? 121.892 110.944 99.751  1.00 16.24  ? 274 ASP A N   1 
ATOM   854  C CA  . ASP A 1 274 ? 123.333 110.993 99.971  1.00 16.24  ? 274 ASP A CA  1 
ATOM   855  C C   . ASP A 1 274 ? 123.861 112.417 99.850  1.00 16.24  ? 274 ASP A C   1 
ATOM   856  O O   . ASP A 1 274 ? 124.691 112.851 100.657 1.00 16.24  ? 274 ASP A O   1 
ATOM   857  C CB  . ASP A 1 274 ? 124.037 110.072 98.975  1.00 16.24  ? 274 ASP A CB  1 
ATOM   858  C CG  . ASP A 1 274 ? 125.536 110.035 99.169  1.00 16.24  ? 274 ASP A CG  1 
ATOM   859  O OD1 . ASP A 1 274 ? 126.043 110.727 100.076 1.00 16.24  ? 274 ASP A OD1 1 
ATOM   860  O OD2 . ASP A 1 274 ? 126.214 109.309 98.413  1.00 16.24  ? 274 ASP A OD2 1 
ATOM   861  N N   . SER A 1 275 ? 123.399 113.159 98.841  1.00 15.60  ? 275 SER A N   1 
ATOM   862  C CA  . SER A 1 275 ? 123.832 114.543 98.683  1.00 15.60  ? 275 SER A CA  1 
ATOM   863  C C   . SER A 1 275 ? 123.390 115.392 99.864  1.00 15.60  ? 275 SER A C   1 
ATOM   864  O O   . SER A 1 275 ? 124.139 116.261 100.321 1.00 15.60  ? 275 SER A O   1 
ATOM   865  C CB  . SER A 1 275 ? 123.283 115.116 97.377  1.00 15.60  ? 275 SER A CB  1 
ATOM   866  O OG  . SER A 1 275 ? 123.656 114.312 96.274  1.00 15.60  ? 275 SER A OG  1 
ATOM   867  N N   . ILE A 1 276 ? 122.175 115.164 100.366 1.00 14.24  ? 276 ILE A N   1 
ATOM   868  C CA  . ILE A 1 276 ? 121.725 115.884 101.555 1.00 14.24  ? 276 ILE A CA  1 
ATOM   869  C C   . ILE A 1 276 ? 122.632 115.571 102.738 1.00 14.24  ? 276 ILE A C   1 
ATOM   870  O O   . ILE A 1 276 ? 123.018 116.466 103.500 1.00 14.24  ? 276 ILE A O   1 
ATOM   871  C CB  . ILE A 1 276 ? 120.255 115.546 101.863 1.00 14.24  ? 276 ILE A CB  1 
ATOM   872  C CG1 . ILE A 1 276 ? 119.327 116.426 101.026 1.00 14.24  ? 276 ILE A CG1 1 
ATOM   873  C CG2 . ILE A 1 276 ? 119.962 115.714 103.351 1.00 14.24  ? 276 ILE A CG2 1 
ATOM   874  C CD1 . ILE A 1 276 ? 117.854 116.106 101.185 1.00 14.24  ? 276 ILE A CD1 1 
ATOM   875  N N   . TRP A 1 277 ? 122.991 114.299 102.906 1.00 17.26  ? 277 TRP A N   1 
ATOM   876  C CA  . TRP A 1 277 ? 123.771 113.880 104.066 1.00 17.26  ? 277 TRP A CA  1 
ATOM   877  C C   . TRP A 1 277 ? 125.070 114.668 104.177 1.00 17.26  ? 277 TRP A C   1 
ATOM   878  O O   . TRP A 1 277 ? 125.429 115.145 105.259 1.00 17.26  ? 277 TRP A O   1 
ATOM   879  C CB  . TRP A 1 277 ? 124.062 112.383 103.970 1.00 17.26  ? 277 TRP A CB  1 
ATOM   880  C CG  . TRP A 1 277 ? 124.246 111.693 105.286 1.00 17.26  ? 277 TRP A CG  1 
ATOM   881  C CD1 . TRP A 1 277 ? 125.356 111.026 105.712 1.00 17.26  ? 277 TRP A CD1 1 
ATOM   882  C CD2 . TRP A 1 277 ? 123.286 111.587 106.343 1.00 17.26  ? 277 TRP A CD2 1 
ATOM   883  N NE1 . TRP A 1 277 ? 125.150 110.517 106.970 1.00 17.26  ? 277 TRP A NE1 1 
ATOM   884  C CE2 . TRP A 1 277 ? 123.886 110.846 107.378 1.00 17.26  ? 277 TRP A CE2 1 
ATOM   885  C CE3 . TRP A 1 277 ? 121.979 112.050 106.514 1.00 17.26  ? 277 TRP A CE3 1 
ATOM   886  C CZ2 . TRP A 1 277 ? 123.226 110.563 108.569 1.00 17.26  ? 277 TRP A CZ2 1 
ATOM   887  C CZ3 . TRP A 1 277 ? 121.325 111.764 107.696 1.00 17.26  ? 277 TRP A CZ3 1 
ATOM   888  C CH2 . TRP A 1 277 ? 121.949 111.029 108.708 1.00 17.26  ? 277 TRP A CH2 1 
ATOM   889  N N   . ASN A 1 278 ? 125.786 114.824 103.064 1.00 16.31  ? 278 ASN A N   1 
ATOM   890  C CA  . ASN A 1 278 ? 127.161 115.302 103.089 1.00 16.31  ? 278 ASN A CA  1 
ATOM   891  C C   . ASN A 1 278 ? 127.304 116.803 102.862 1.00 16.31  ? 278 ASN A C   1 
ATOM   892  O O   . ASN A 1 278 ? 128.435 117.284 102.732 1.00 16.31  ? 278 ASN A O   1 
ATOM   893  C CB  . ASN A 1 278 ? 127.987 114.557 102.036 1.00 16.31  ? 278 ASN A CB  1 
ATOM   894  C CG  . ASN A 1 278 ? 128.148 113.089 102.360 1.00 16.31  ? 278 ASN A CG  1 
ATOM   895  O OD1 . ASN A 1 278 ? 127.450 112.242 101.807 1.00 16.31  ? 278 ASN A OD1 1 
ATOM   896  N ND2 . ASN A 1 278 ? 129.068 112.779 103.261 1.00 16.31  ? 278 ASN A ND2 1 
ATOM   897  N N   . ASN A 1 279 ? 126.209 117.556 102.808 1.00 18.91  ? 279 ASN A N   1 
ATOM   898  C CA  . ASN A 1 279 ? 126.306 118.999 102.625 1.00 18.91  ? 279 ASN A CA  1 
ATOM   899  C C   . ASN A 1 279 ? 126.645 119.659 103.954 1.00 18.91  ? 279 ASN A C   1 
ATOM   900  O O   . ASN A 1 279 ? 126.025 119.358 104.979 1.00 18.91  ? 279 ASN A O   1 
ATOM   901  C CB  . ASN A 1 279 ? 125.000 119.555 102.066 1.00 18.91  ? 279 ASN A CB  1 
ATOM   902  C CG  . ASN A 1 279 ? 125.133 120.990 101.607 1.00 18.91  ? 279 ASN A CG  1 
ATOM   903  O OD1 . ASN A 1 279 ? 126.229 121.547 101.591 1.00 18.91  ? 279 ASN A OD1 1 
ATOM   904  N ND2 . ASN A 1 279 ? 124.019 121.594 101.219 1.00 18.91  ? 279 ASN A ND2 1 
ATOM   905  N N   . LYS A 1 280 ? 127.621 120.569 103.938 1.00 18.08  ? 280 LYS A N   1 
ATOM   906  C CA  . LYS A 1 280 ? 128.132 121.116 105.190 1.00 18.08  ? 280 LYS A CA  1 
ATOM   907  C C   . LYS A 1 280 ? 127.069 121.899 105.948 1.00 18.08  ? 280 LYS A C   1 
ATOM   908  O O   . LYS A 1 280 ? 126.999 121.813 107.177 1.00 18.08  ? 280 LYS A O   1 
ATOM   909  C CB  . LYS A 1 280 ? 129.352 121.996 104.928 1.00 18.08  ? 280 LYS A CB  1 
ATOM   910  C CG  . LYS A 1 280 ? 129.154 123.077 103.885 1.00 18.08  ? 280 LYS A CG  1 
ATOM   911  C CD  . LYS A 1 280 ? 130.443 123.851 103.671 1.00 18.08  ? 280 LYS A CD  1 
ATOM   912  C CE  . LYS A 1 280 ? 130.362 124.761 102.463 1.00 18.08  ? 280 LYS A CE  1 
ATOM   913  N NZ  . LYS A 1 280 ? 131.657 125.447 102.212 1.00 18.08  ? 280 LYS A NZ  1 
ATOM   914  N N   . TRP A 1 281 ? 126.235 122.665 105.243 1.00 14.90  ? 281 TRP A N   1 
ATOM   915  C CA  . TRP A 1 281 ? 125.207 123.447 105.920 1.00 14.90  ? 281 TRP A CA  1 
ATOM   916  C C   . TRP A 1 281 ? 124.107 122.575 106.501 1.00 14.90  ? 281 TRP A C   1 
ATOM   917  O O   . TRP A 1 281 ? 123.266 123.078 107.250 1.00 14.90  ? 281 TRP A O   1 
ATOM   918  C CB  . TRP A 1 281 ? 124.603 124.467 104.959 1.00 14.90  ? 281 TRP A CB  1 
ATOM   919  C CG  . TRP A 1 281 ? 125.633 125.262 104.245 1.00 14.90  ? 281 TRP A CG  1 
ATOM   920  C CD1 . TRP A 1 281 ? 125.812 125.353 102.899 1.00 14.90  ? 281 TRP A CD1 1 
ATOM   921  C CD2 . TRP A 1 281 ? 126.648 126.073 104.841 1.00 14.90  ? 281 TRP A CD2 1 
ATOM   922  N NE1 . TRP A 1 281 ? 126.872 126.177 102.618 1.00 14.90  ? 281 TRP A NE1 1 
ATOM   923  C CE2 . TRP A 1 281 ? 127.404 126.631 103.795 1.00 14.90  ? 281 TRP A CE2 1 
ATOM   924  C CE3 . TRP A 1 281 ? 126.991 126.383 106.159 1.00 14.90  ? 281 TRP A CE3 1 
ATOM   925  C CZ2 . TRP A 1 281 ? 128.479 127.482 104.026 1.00 14.90  ? 281 TRP A CZ2 1 
ATOM   926  C CZ3 . TRP A 1 281 ? 128.057 127.225 106.385 1.00 14.90  ? 281 TRP A CZ3 1 
ATOM   927  C CH2 . TRP A 1 281 ? 128.789 127.766 105.325 1.00 14.90  ? 281 TRP A CH2 1 
ATOM   928  N N   . LEU A 1 282 ? 124.095 121.286 106.172 1.00 18.09  ? 282 LEU A N   1 
ATOM   929  C CA  . LEU A 1 282 ? 123.092 120.358 106.666 1.00 18.09  ? 282 LEU A CA  1 
ATOM   930  C C   . LEU A 1 282 ? 123.681 119.239 107.512 1.00 18.09  ? 282 LEU A C   1 
ATOM   931  O O   . LEU A 1 282 ? 122.994 118.242 107.750 1.00 18.09  ? 282 LEU A O   1 
ATOM   932  C CB  . LEU A 1 282 ? 122.321 119.748 105.488 1.00 18.09  ? 282 LEU A CB  1 
ATOM   933  C CG  . LEU A 1 282 ? 121.768 120.767 104.490 1.00 18.09  ? 282 LEU A CG  1 
ATOM   934  C CD1 . LEU A 1 282 ? 121.153 120.063 103.295 1.00 18.09  ? 282 LEU A CD1 1 
ATOM   935  C CD2 . LEU A 1 282 ? 120.751 121.673 105.159 1.00 18.09  ? 282 LEU A CD2 1 
ATOM   936  N N   . ARG A 1 283 ? 124.925 119.378 107.970 1.00 22.64  ? 283 ARG A N   1 
ATOM   937  C CA  . ARG A 1 283 ? 125.591 118.329 108.733 1.00 22.64  ? 283 ARG A CA  1 
ATOM   938  C C   . ARG A 1 283 ? 125.192 118.372 110.203 1.00 22.64  ? 283 ARG A C   1 
ATOM   939  O O   . ARG A 1 283 ? 125.865 117.776 111.047 1.00 22.64  ? 283 ARG A O   1 
ATOM   940  C CB  . ARG A 1 283 ? 127.108 118.461 108.595 1.00 22.64  ? 283 ARG A CB  1 
ATOM   941  C CG  . ARG A 1 283 ? 127.680 117.767 107.373 1.00 22.64  ? 283 ARG A CG  1 
ATOM   942  C CD  . ARG A 1 283 ? 129.196 117.701 107.431 1.00 22.64  ? 283 ARG A CD  1 
ATOM   943  N NE  . ARG A 1 283 ? 129.797 117.969 106.129 1.00 22.64  ? 283 ARG A NE  1 
ATOM   944  C CZ  . ARG A 1 283 ? 130.899 118.682 105.933 1.00 22.64  ? 283 ARG A CZ  1 
ATOM   945  N NH1 . ARG A 1 283 ? 131.588 119.189 106.943 1.00 22.64  ? 283 ARG A NH1 1 
ATOM   946  N NH2 . ARG A 1 283 ? 131.321 118.893 104.689 1.00 22.64  ? 283 ARG A NH2 1 
ATOM   947  N N   . ASP A 1 284 ? 124.119 119.091 110.523 1.00 20.41  ? 284 ASP A N   1 
ATOM   948  C CA  . ASP A 1 284 ? 123.572 119.119 111.871 1.00 20.41  ? 284 ASP A CA  1 
ATOM   949  C C   . ASP A 1 284 ? 122.053 119.047 111.892 1.00 20.41  ? 284 ASP A C   1 
ATOM   950  O O   . ASP A 1 284 ? 121.462 119.087 112.976 1.00 20.41  ? 284 ASP A O   1 
ATOM   951  C CB  . ASP A 1 284 ? 124.026 120.387 112.606 1.00 20.41  ? 284 ASP A CB  1 
ATOM   952  C CG  . ASP A 1 284 ? 125.508 120.385 112.918 1.00 20.41  ? 284 ASP A CG  1 
ATOM   953  O OD1 . ASP A 1 284 ? 126.078 119.290 113.097 1.00 20.41  ? 284 ASP A OD1 1 
ATOM   954  O OD2 . ASP A 1 284 ? 126.104 121.478 112.989 1.00 20.41  ? 284 ASP A OD2 1 
ATOM   955  N N   . THR A 1 285 ? 121.408 118.946 110.735 1.00 17.07  ? 285 THR A N   1 
ATOM   956  C CA  . THR A 1 285 ? 119.955 118.916 110.638 1.00 17.07  ? 285 THR A CA  1 
ATOM   957  C C   . THR A 1 285 ? 119.496 117.470 110.528 1.00 17.07  ? 285 THR A C   1 
ATOM   958  O O   . THR A 1 285 ? 119.920 116.749 109.620 1.00 17.07  ? 285 THR A O   1 
ATOM   959  C CB  . THR A 1 285 ? 119.481 119.721 109.429 1.00 17.07  ? 285 THR A CB  1 
ATOM   960  O OG1 . THR A 1 285 ? 119.878 121.089 109.581 1.00 17.07  ? 285 THR A OG1 1 
ATOM   961  C CG2 . THR A 1 285 ? 117.974 119.645 109.291 1.00 17.07  ? 285 THR A CG2 1 
ATOM   962  N N   . SER A 1 286 ? 118.636 117.050 111.449 1.00 16.52  ? 286 SER A N   1 
ATOM   963  C CA  . SER A 1 286 ? 118.135 115.686 111.430 1.00 16.52  ? 286 SER A CA  1 
ATOM   964  C C   . SER A 1 286 ? 117.171 115.490 110.268 1.00 16.52  ? 286 SER A C   1 
ATOM   965  O O   . SER A 1 286 ? 116.489 116.419 109.832 1.00 16.52  ? 286 SER A O   1 
ATOM   966  C CB  . SER A 1 286 ? 117.441 115.359 112.747 1.00 16.52  ? 286 SER A CB  1 
ATOM   967  O OG  . SER A 1 286 ? 118.342 115.503 113.827 1.00 16.52  ? 286 SER A OG  1 
ATOM   968  N N   . VAL A 1 287 ? 117.120 114.260 109.764 1.00 13.72  ? 287 VAL A N   1 
ATOM   969  C CA  . VAL A 1 287 ? 116.289 113.911 108.619 1.00 13.72  ? 287 VAL A CA  1 
ATOM   970  C C   . VAL A 1 287 ? 115.464 112.690 108.992 1.00 13.72  ? 287 VAL A C   1 
ATOM   971  O O   . VAL A 1 287 ? 116.021 111.626 109.285 1.00 13.72  ? 287 VAL A O   1 
ATOM   972  C CB  . VAL A 1 287 ? 117.126 113.634 107.364 1.00 13.72  ? 287 VAL A CB  1 
ATOM   973  C CG1 . VAL A 1 287 ? 116.278 112.969 106.293 1.00 13.72  ? 287 VAL A CG1 1 
ATOM   974  C CG2 . VAL A 1 287 ? 117.737 114.923 106.844 1.00 13.72  ? 287 VAL A CG2 1 
ATOM   975  N N   . ILE A 1 288 ? 114.153 112.832 108.977 1.00 13.30  ? 288 ILE A N   1 
ATOM   976  C CA  . ILE A 1 288 ? 113.252 111.700 109.138 1.00 13.30  ? 288 ILE A CA  1 
ATOM   977  C C   . ILE A 1 288 ? 113.052 111.072 107.769 1.00 13.30  ? 288 ILE A C   1 
ATOM   978  O O   . ILE A 1 288 ? 113.062 111.759 106.742 1.00 13.30  ? 288 ILE A O   1 
ATOM   979  C CB  . ILE A 1 288 ? 111.914 112.131 109.772 1.00 13.30  ? 288 ILE A CB  1 
ATOM   980  C CG1 . ILE A 1 288 ? 112.158 112.714 111.162 1.00 13.30  ? 288 ILE A CG1 1 
ATOM   981  C CG2 . ILE A 1 288 ? 110.961 110.953 109.861 1.00 13.30  ? 288 ILE A CG2 1 
ATOM   982  C CD1 . ILE A 1 288 ? 110.963 113.411 111.745 1.00 13.30  ? 288 ILE A CD1 1 
ATOM   983  N N   . LEU A 1 289 ? 112.878 109.755 107.744 1.00 15.00  ? 289 LEU A N   1 
ATOM   984  C CA  . LEU A 1 289 ? 112.807 108.997 106.502 1.00 15.00  ? 289 LEU A CA  1 
ATOM   985  C C   . LEU A 1 289 ? 111.509 108.206 106.473 1.00 15.00  ? 289 LEU A C   1 
ATOM   986  O O   . LEU A 1 289 ? 111.224 107.438 107.397 1.00 15.00  ? 289 LEU A O   1 
ATOM   987  C CB  . LEU A 1 289 ? 114.009 108.061 106.369 1.00 15.00  ? 289 LEU A CB  1 
ATOM   988  C CG  . LEU A 1 289 ? 114.262 107.475 104.981 1.00 15.00  ? 289 LEU A CG  1 
ATOM   989  C CD1 . LEU A 1 289 ? 114.711 108.557 104.016 1.00 15.00  ? 289 LEU A CD1 1 
ATOM   990  C CD2 . LEU A 1 289 ? 115.286 106.365 105.056 1.00 15.00  ? 289 LEU A CD2 1 
ATOM   991  N N   . PHE A 1 290 ? 110.725 108.402 105.420 1.00 19.43  ? 290 PHE A N   1 
ATOM   992  C CA  . PHE A 1 290 ? 109.498 107.655 105.186 1.00 19.43  ? 290 PHE A CA  1 
ATOM   993  C C   . PHE A 1 290 ? 109.653 106.857 103.901 1.00 19.43  ? 290 PHE A C   1 
ATOM   994  O O   . PHE A 1 290 ? 110.085 107.397 102.877 1.00 19.43  ? 290 PHE A O   1 
ATOM   995  C CB  . PHE A 1 290 ? 108.285 108.586 105.076 1.00 19.43  ? 290 PHE A CB  1 
ATOM   996  C CG  . PHE A 1 290 ? 107.736 109.049 106.396 1.00 19.43  ? 290 PHE A CG  1 
ATOM   997  C CD1 . PHE A 1 290 ? 108.522 109.080 107.533 1.00 19.43  ? 290 PHE A CD1 1 
ATOM   998  C CD2 . PHE A 1 290 ? 106.423 109.470 106.493 1.00 19.43  ? 290 PHE A CD2 1 
ATOM   999  C CE1 . PHE A 1 290 ? 108.004 109.513 108.742 1.00 19.43  ? 290 PHE A CE1 1 
ATOM   1000 C CE2 . PHE A 1 290 ? 105.902 109.903 107.697 1.00 19.43  ? 290 PHE A CE2 1 
ATOM   1001 C CZ  . PHE A 1 290 ? 106.694 109.925 108.822 1.00 19.43  ? 290 PHE A CZ  1 
ATOM   1002 N N   . LEU A 1 291 ? 109.302 105.579 103.956 1.00 24.05  ? 291 LEU A N   1 
ATOM   1003 C CA  . LEU A 1 291 ? 109.275 104.695 102.795 1.00 24.05  ? 291 LEU A CA  1 
ATOM   1004 C C   . LEU A 1 291 ? 107.798 104.412 102.536 1.00 24.05  ? 291 LEU A C   1 
ATOM   1005 O O   . LEU A 1 291 ? 107.217 103.485 103.102 1.00 24.05  ? 291 LEU A O   1 
ATOM   1006 C CB  . LEU A 1 291 ? 110.085 103.429 103.056 1.00 24.05  ? 291 LEU A CB  1 
ATOM   1007 C CG  . LEU A 1 291 ? 111.474 103.680 103.654 1.00 24.05  ? 291 LEU A CG  1 
ATOM   1008 C CD1 . LEU A 1 291 ? 111.996 102.443 104.342 1.00 24.05  ? 291 LEU A CD1 1 
ATOM   1009 C CD2 . LEU A 1 291 ? 112.447 104.136 102.589 1.00 24.05  ? 291 LEU A CD2 1 
ATOM   1010 N N   . ASN A 1 292 ? 107.192 105.221 101.670 1.00 27.24  ? 292 ASN A N   1 
ATOM   1011 C CA  . ASN A 1 292 ? 105.745 105.428 101.658 1.00 27.24  ? 292 ASN A CA  1 
ATOM   1012 C C   . ASN A 1 292 ? 105.043 104.705 100.520 1.00 27.24  ? 292 ASN A C   1 
ATOM   1013 O O   . ASN A 1 292 ? 104.119 105.254 99.918  1.00 27.24  ? 292 ASN A O   1 
ATOM   1014 C CB  . ASN A 1 292 ? 105.442 106.921 101.597 1.00 27.24  ? 292 ASN A CB  1 
ATOM   1015 C CG  . ASN A 1 292 ? 104.070 107.264 102.147 1.00 27.24  ? 292 ASN A CG  1 
ATOM   1016 O OD1 . ASN A 1 292 ? 103.064 106.671 101.759 1.00 27.24  ? 292 ASN A OD1 1 
ATOM   1017 N ND2 . ASN A 1 292 ? 104.026 108.220 103.065 1.00 27.24  ? 292 ASN A ND2 1 
ATOM   1018 N N   . LYS A 1 293 ? 105.451 103.488 100.180 1.00 31.89  ? 293 LYS A N   1 
ATOM   1019 C CA  . LYS A 1 293 ? 104.702 102.700 99.209  1.00 31.89  ? 293 LYS A CA  1 
ATOM   1020 C C   . LYS A 1 293 ? 104.678 101.233 99.612  1.00 31.89  ? 293 LYS A C   1 
ATOM   1021 O O   . LYS A 1 293 ? 104.890 100.341 98.785  1.00 31.89  ? 293 LYS A O   1 
ATOM   1022 C CB  . LYS A 1 293 ? 105.274 102.869 97.805  1.00 31.89  ? 293 LYS A CB  1 
ATOM   1023 C CG  . LYS A 1 293 ? 104.981 104.227 97.179  1.00 31.89  ? 293 LYS A CG  1 
ATOM   1024 C CD  . LYS A 1 293 ? 103.492 104.417 96.936  1.00 31.89  ? 293 LYS A CD  1 
ATOM   1025 C CE  . LYS A 1 293 ? 103.227 105.505 95.912  1.00 31.89  ? 293 LYS A CE  1 
ATOM   1026 N NZ  . LYS A 1 293 ? 103.480 105.039 94.522  1.00 31.89  ? 293 LYS A NZ  1 
ATOM   1027 N N   . GLN A 1 294 ? 104.425 100.959 100.892 1.00 31.00  ? 294 GLN A N   1 
ATOM   1028 C CA  . GLN A 1 294 ? 104.456 99.579  101.368 1.00 31.00  ? 294 GLN A CA  1 
ATOM   1029 C C   . GLN A 1 294 ? 103.346 98.749  100.737 1.00 31.00  ? 294 GLN A C   1 
ATOM   1030 O O   . GLN A 1 294 ? 103.577 97.617  100.295 1.00 31.00  ? 294 GLN A O   1 
ATOM   1031 C CB  . GLN A 1 294 ? 104.347 99.549  102.894 1.00 31.00  ? 294 GLN A CB  1 
ATOM   1032 C CG  . GLN A 1 294 ? 105.556 100.107 103.632 1.00 31.00  ? 294 GLN A CG  1 
ATOM   1033 C CD  . GLN A 1 294 ? 106.874 99.592  103.094 1.00 31.00  ? 294 GLN A CD  1 
ATOM   1034 O OE1 . GLN A 1 294 ? 106.953 98.485  102.565 1.00 31.00  ? 294 GLN A OE1 1 
ATOM   1035 N NE2 . GLN A 1 294 ? 107.920 100.394 103.231 1.00 31.00  ? 294 GLN A NE2 1 
ATOM   1036 N N   . ASP A 1 295 ? 102.128 99.293  100.684 1.00 38.32  ? 295 ASP A N   1 
ATOM   1037 C CA  . ASP A 1 295 ? 100.996 98.527  100.178 1.00 38.32  ? 295 ASP A CA  1 
ATOM   1038 C C   . ASP A 1 295 ? 101.066 98.292  98.677  1.00 38.32  ? 295 ASP A C   1 
ATOM   1039 O O   . ASP A 1 295 ? 100.308 97.463  98.162  1.00 38.32  ? 295 ASP A O   1 
ATOM   1040 C CB  . ASP A 1 295 ? 99.688  99.232  100.529 1.00 38.32  ? 295 ASP A CB  1 
ATOM   1041 C CG  . ASP A 1 295 ? 99.172  98.842  101.898 1.00 38.32  ? 295 ASP A CG  1 
ATOM   1042 O OD1 . ASP A 1 295 ? 99.999  98.494  102.766 1.00 38.32  ? 295 ASP A OD1 1 
ATOM   1043 O OD2 . ASP A 1 295 ? 97.942  98.878  102.105 1.00 38.32  ? 295 ASP A OD2 1 
ATOM   1044 N N   . LEU A 1 296 ? 101.941 98.998  97.966  1.00 40.53  ? 296 LEU A N   1 
ATOM   1045 C CA  . LEU A 1 296 ? 102.215 98.736  96.559  1.00 40.53  ? 296 LEU A CA  1 
ATOM   1046 C C   . LEU A 1 296 ? 103.450 97.867  96.366  1.00 40.53  ? 296 LEU A C   1 
ATOM   1047 O O   . LEU A 1 296 ? 103.473 97.013  95.473  1.00 40.53  ? 296 LEU A O   1 
ATOM   1048 C CB  . LEU A 1 296 ? 102.393 100.058 95.805  1.00 40.53  ? 296 LEU A CB  1 
ATOM   1049 C CG  . LEU A 1 296 ? 102.764 99.973  94.325  1.00 40.53  ? 296 LEU A CG  1 
ATOM   1050 C CD1 . LEU A 1 296 ? 101.824 99.034  93.585  1.00 40.53  ? 296 LEU A CD1 1 
ATOM   1051 C CD2 . LEU A 1 296 ? 102.738 101.356 93.696  1.00 40.53  ? 296 LEU A CD2 1 
ATOM   1052 N N   . LEU A 1 297 ? 104.474 98.068  97.198  1.00 39.25  ? 297 LEU A N   1 
ATOM   1053 C CA  . LEU A 1 297 ? 105.626 97.176  97.181  1.00 39.25  ? 297 LEU A CA  1 
ATOM   1054 C C   . LEU A 1 297 ? 105.213 95.744  97.479  1.00 39.25  ? 297 LEU A C   1 
ATOM   1055 O O   . LEU A 1 297 ? 105.794 94.804  96.924  1.00 39.25  ? 297 LEU A O   1 
ATOM   1056 C CB  . LEU A 1 297 ? 106.668 97.649  98.195  1.00 39.25  ? 297 LEU A CB  1 
ATOM   1057 C CG  . LEU A 1 297 ? 107.842 96.709  98.479  1.00 39.25  ? 297 LEU A CG  1 
ATOM   1058 C CD1 . LEU A 1 297 ? 108.554 96.313  97.197  1.00 39.25  ? 297 LEU A CD1 1 
ATOM   1059 C CD2 . LEU A 1 297 ? 108.815 97.361  99.442  1.00 39.25  ? 297 LEU A CD2 1 
ATOM   1060 N N   . ALA A 1 298 ? 104.218 95.557  98.346  1.00 44.26  ? 298 ALA A N   1 
ATOM   1061 C CA  . ALA A 1 298 ? 103.758 94.207  98.657  1.00 44.26  ? 298 ALA A CA  1 
ATOM   1062 C C   . ALA A 1 298 ? 103.286 93.489  97.400  1.00 44.26  ? 298 ALA A C   1 
ATOM   1063 O O   . ALA A 1 298 ? 103.729 92.372  97.103  1.00 44.26  ? 298 ALA A O   1 
ATOM   1064 C CB  . ALA A 1 298 ? 102.640 94.265  99.697  1.00 44.26  ? 298 ALA A CB  1 
ATOM   1065 N N   . GLU A 1 299 ? 102.389 94.119  96.639  1.00 47.22  ? 299 GLU A N   1 
ATOM   1066 C CA  . GLU A 1 299 ? 101.905 93.498  95.410  1.00 47.22  ? 299 GLU A CA  1 
ATOM   1067 C C   . GLU A 1 299 ? 103.021 93.359  94.384  1.00 47.22  ? 299 GLU A C   1 
ATOM   1068 O O   . GLU A 1 299 ? 103.098 92.345  93.682  1.00 47.22  ? 299 GLU A O   1 
ATOM   1069 C CB  . GLU A 1 299 ? 100.746 94.309  94.833  1.00 47.22  ? 299 GLU A CB  1 
ATOM   1070 N N   . LYS A 1 300 ? 103.896 94.362  94.277  1.00 45.43  ? 300 LYS A N   1 
ATOM   1071 C CA  . LYS A 1 300 ? 104.967 94.295  93.288  1.00 45.43  ? 300 LYS A CA  1 
ATOM   1072 C C   . LYS A 1 300 ? 105.873 93.096  93.540  1.00 45.43  ? 300 LYS A C   1 
ATOM   1073 O O   . LYS A 1 300 ? 106.195 92.340  92.616  1.00 45.43  ? 300 LYS A O   1 
ATOM   1074 C CB  . LYS A 1 300 ? 105.779 95.591  93.304  1.00 45.43  ? 300 LYS A CB  1 
ATOM   1075 C CG  . LYS A 1 300 ? 105.140 96.727  92.528  1.00 45.43  ? 300 LYS A CG  1 
ATOM   1076 C CD  . LYS A 1 300 ? 106.063 97.932  92.447  1.00 45.43  ? 300 LYS A CD  1 
ATOM   1077 C CE  . LYS A 1 300 ? 107.128 97.745  91.381  1.00 45.43  ? 300 LYS A CE  1 
ATOM   1078 N NZ  . LYS A 1 300 ? 107.869 99.004  91.104  1.00 45.43  ? 300 LYS A NZ  1 
ATOM   1079 N N   . VAL A 1 301 ? 106.296 92.904  94.790  1.00 45.29  ? 301 VAL A N   1 
ATOM   1080 C CA  . VAL A 1 301 ? 107.183 91.790  95.105  1.00 45.29  ? 301 VAL A CA  1 
ATOM   1081 C C   . VAL A 1 301 ? 106.432 90.465  95.027  1.00 45.29  ? 301 VAL A C   1 
ATOM   1082 O O   . VAL A 1 301 ? 106.974 89.460  94.552  1.00 45.29  ? 301 VAL A O   1 
ATOM   1083 C CB  . VAL A 1 301 ? 107.833 91.998  96.485  1.00 45.29  ? 301 VAL A CB  1 
ATOM   1084 C CG1 . VAL A 1 301 ? 106.808 91.855  97.597  1.00 45.29  ? 301 VAL A CG1 1 
ATOM   1085 C CG2 . VAL A 1 301 ? 108.981 91.019  96.682  1.00 45.29  ? 301 VAL A CG2 1 
ATOM   1086 N N   . LEU A 1 302 ? 105.182 90.435  95.493  1.00 46.96  ? 302 LEU A N   1 
ATOM   1087 C CA  . LEU A 1 302 ? 104.440 89.178  95.533  1.00 46.96  ? 302 LEU A CA  1 
ATOM   1088 C C   . LEU A 1 302 ? 104.163 88.651  94.130  1.00 46.96  ? 302 LEU A C   1 
ATOM   1089 O O   . LEU A 1 302 ? 104.334 87.457  93.860  1.00 46.96  ? 302 LEU A O   1 
ATOM   1090 C CB  . LEU A 1 302 ? 103.130 89.368  96.299  1.00 46.96  ? 302 LEU A CB  1 
ATOM   1091 C CG  . LEU A 1 302 ? 103.187 89.365  97.829  1.00 46.96  ? 302 LEU A CG  1 
ATOM   1092 C CD1 . LEU A 1 302 ? 101.777 89.369  98.396  1.00 46.96  ? 302 LEU A CD1 1 
ATOM   1093 C CD2 . LEU A 1 302 ? 103.969 88.178  98.366  1.00 46.96  ? 302 LEU A CD2 1 
ATOM   1094 N N   . ALA A 1 303 ? 103.734 89.526  93.220  1.00 51.48  ? 303 ALA A N   1 
ATOM   1095 C CA  . ALA A 1 303 ? 103.317 89.089  91.895  1.00 51.48  ? 303 ALA A CA  1 
ATOM   1096 C C   . ALA A 1 303 ? 104.460 88.516  91.068  1.00 51.48  ? 303 ALA A C   1 
ATOM   1097 O O   . ALA A 1 303 ? 104.195 87.880  90.042  1.00 51.48  ? 303 ALA A O   1 
ATOM   1098 C CB  . ALA A 1 303 ? 102.675 90.252  91.138  1.00 51.48  ? 303 ALA A CB  1 
ATOM   1099 N N   . GLY A 1 304 ? 105.708 88.719  91.478  1.00 55.13  ? 304 GLY A N   1 
ATOM   1100 C CA  . GLY A 1 304 ? 106.845 88.225  90.730  1.00 55.13  ? 304 GLY A CA  1 
ATOM   1101 C C   . GLY A 1 304 ? 107.389 89.173  89.687  1.00 55.13  ? 304 GLY A C   1 
ATOM   1102 O O   . GLY A 1 304 ? 108.300 88.791  88.943  1.00 55.13  ? 304 GLY A O   1 
ATOM   1103 N N   . LYS A 1 305 ? 106.860 90.394  89.603  1.00 51.72  ? 305 LYS A N   1 
ATOM   1104 C CA  . LYS A 1 305 ? 107.350 91.384  88.652  1.00 51.72  ? 305 LYS A CA  1 
ATOM   1105 C C   . LYS A 1 305 ? 108.589 92.120  89.148  1.00 51.72  ? 305 LYS A C   1 
ATOM   1106 O O   . LYS A 1 305 ? 109.267 92.768  88.344  1.00 51.72  ? 305 LYS A O   1 
ATOM   1107 C CB  . LYS A 1 305 ? 106.238 92.392  88.346  1.00 51.72  ? 305 LYS A CB  1 
ATOM   1108 N N   . SER A 1 306 ? 108.907 92.028  90.438  1.00 53.11  ? 306 SER A N   1 
ATOM   1109 C CA  . SER A 1 306 ? 109.984 92.820  91.017  1.00 53.11  ? 306 SER A CA  1 
ATOM   1110 C C   . SER A 1 306 ? 111.334 92.509  90.384  1.00 53.11  ? 306 SER A C   1 
ATOM   1111 O O   . SER A 1 306 ? 111.916 93.359  89.704  1.00 53.11  ? 306 SER A O   1 
ATOM   1112 C CB  . SER A 1 306 ? 110.060 92.576  92.524  1.00 53.11  ? 306 SER A CB  1 
ATOM   1113 N N   . LYS A 1 307 ? 111.823 91.291  90.592  1.00 51.94  ? 307 LYS A N   1 
ATOM   1114 C CA  . LYS A 1 307 ? 113.162 90.888  90.168  1.00 51.94  ? 307 LYS A CA  1 
ATOM   1115 C C   . LYS A 1 307 ? 114.178 91.986  90.482  1.00 51.94  ? 307 LYS A C   1 
ATOM   1116 O O   . LYS A 1 307 ? 114.890 92.492  89.615  1.00 51.94  ? 307 LYS A O   1 
ATOM   1117 C CB  . LYS A 1 307 ? 113.179 90.532  88.681  1.00 51.94  ? 307 LYS A CB  1 
ATOM   1118 C CG  . LYS A 1 307 ? 114.427 89.778  88.225  1.00 51.94  ? 307 LYS A CG  1 
ATOM   1119 C CD  . LYS A 1 307 ? 114.717 88.523  89.047  1.00 51.94  ? 307 LYS A CD  1 
ATOM   1120 C CE  . LYS A 1 307 ? 113.462 87.715  89.351  1.00 51.94  ? 307 LYS A CE  1 
ATOM   1121 N NZ  . LYS A 1 307 ? 113.792 86.327  89.775  1.00 51.94  ? 307 LYS A NZ  1 
ATOM   1122 N N   . ILE A 1 308 ? 114.233 92.346  91.766  1.00 42.17  ? 308 ILE A N   1 
ATOM   1123 C CA  . ILE A 1 308 ? 115.125 93.409  92.213  1.00 42.17  ? 308 ILE A CA  1 
ATOM   1124 C C   . ILE A 1 308 ? 116.584 93.044  91.993  1.00 42.17  ? 308 ILE A C   1 
ATOM   1125 O O   . ILE A 1 308 ? 117.455 93.919  92.042  1.00 42.17  ? 308 ILE A O   1 
ATOM   1126 C CB  . ILE A 1 308 ? 114.859 93.732  93.699  1.00 42.17  ? 308 ILE A CB  1 
ATOM   1127 C CG1 . ILE A 1 308 ? 113.429 94.242  93.889  1.00 42.17  ? 308 ILE A CG1 1 
ATOM   1128 C CG2 . ILE A 1 308 ? 115.843 94.771  94.206  1.00 42.17  ? 308 ILE A CG2 1 
ATOM   1129 C CD1 . ILE A 1 308 ? 112.905 94.065  95.296  1.00 42.17  ? 308 ILE A CD1 1 
ATOM   1130 N N   . GLU A 1 309 ? 116.879 91.767  91.745  1.00 41.53  ? 309 GLU A N   1 
ATOM   1131 C CA  . GLU A 1 309 ? 118.266 91.350  91.575  1.00 41.53  ? 309 GLU A CA  1 
ATOM   1132 C C   . GLU A 1 309 ? 118.910 92.027  90.372  1.00 41.53  ? 309 GLU A C   1 
ATOM   1133 O O   . GLU A 1 309 ? 120.084 92.412  90.424  1.00 41.53  ? 309 GLU A O   1 
ATOM   1134 C CB  . GLU A 1 309 ? 118.337 89.830  91.435  1.00 41.53  ? 309 GLU A CB  1 
ATOM   1135 C CG  . GLU A 1 309 ? 119.747 89.281  91.292  1.00 41.53  ? 309 GLU A CG  1 
ATOM   1136 C CD  . GLU A 1 309 ? 120.594 89.509  92.527  1.00 41.53  ? 309 GLU A CD  1 
ATOM   1137 O OE1 . GLU A 1 309 ? 120.021 89.628  93.631  1.00 41.53  ? 309 GLU A OE1 1 
ATOM   1138 O OE2 . GLU A 1 309 ? 121.833 89.563  92.395  1.00 41.53  ? 309 GLU A OE2 1 
ATOM   1139 N N   . ASP A 1 310 ? 118.162 92.179  89.275  1.00 42.94  ? 310 ASP A N   1 
ATOM   1140 C CA  . ASP A 1 310 ? 118.748 92.733  88.058  1.00 42.94  ? 310 ASP A CA  1 
ATOM   1141 C C   . ASP A 1 310 ? 119.240 94.158  88.276  1.00 42.94  ? 310 ASP A C   1 
ATOM   1142 O O   . ASP A 1 310 ? 120.316 94.531  87.796  1.00 42.94  ? 310 ASP A O   1 
ATOM   1143 C CB  . ASP A 1 310 ? 117.732 92.684  86.916  1.00 42.94  ? 310 ASP A CB  1 
ATOM   1144 C CG  . ASP A 1 310 ? 116.502 93.526  87.192  1.00 42.94  ? 310 ASP A CG  1 
ATOM   1145 O OD1 . ASP A 1 310 ? 116.420 94.128  88.282  1.00 42.94  ? 310 ASP A OD1 1 
ATOM   1146 O OD2 . ASP A 1 310 ? 115.616 93.588  86.314  1.00 42.94  ? 310 ASP A OD2 1 
ATOM   1147 N N   . TYR A 1 311 ? 118.469 94.968  88.994  1.00 37.81  ? 311 TYR A N   1 
ATOM   1148 C CA  . TYR A 1 311 ? 118.844 96.348  89.274  1.00 37.81  ? 311 TYR A CA  1 
ATOM   1149 C C   . TYR A 1 311 ? 119.632 96.493  90.567  1.00 37.81  ? 311 TYR A C   1 
ATOM   1150 O O   . TYR A 1 311 ? 119.975 97.619  90.942  1.00 37.81  ? 311 TYR A O   1 
ATOM   1151 C CB  . TYR A 1 311 ? 117.594 97.233  89.332  1.00 37.81  ? 311 TYR A CB  1 
ATOM   1152 C CG  . TYR A 1 311 ? 116.864 97.371  88.011  1.00 37.81  ? 311 TYR A CG  1 
ATOM   1153 C CD1 . TYR A 1 311 ? 117.270 96.665  86.885  1.00 37.81  ? 311 TYR A CD1 1 
ATOM   1154 C CD2 . TYR A 1 311 ? 115.769 98.215  87.890  1.00 37.81  ? 311 TYR A CD2 1 
ATOM   1155 C CE1 . TYR A 1 311 ? 116.605 96.792  85.683  1.00 37.81  ? 311 TYR A CE1 1 
ATOM   1156 C CE2 . TYR A 1 311 ? 115.100 98.349  86.690  1.00 37.81  ? 311 TYR A CE2 1 
ATOM   1157 C CZ  . TYR A 1 311 ? 115.521 97.635  85.591  1.00 37.81  ? 311 TYR A CZ  1 
ATOM   1158 O OH  . TYR A 1 311 ? 114.857 97.764  84.393  1.00 37.81  ? 311 TYR A OH  1 
ATOM   1159 N N   . PHE A 1 312 ? 119.923 95.392  91.255  1.00 35.39  ? 312 PHE A N   1 
ATOM   1160 C CA  . PHE A 1 312 ? 120.733 95.418  92.473  1.00 35.39  ? 312 PHE A CA  1 
ATOM   1161 C C   . PHE A 1 312 ? 121.419 94.071  92.619  1.00 35.39  ? 312 PHE A C   1 
ATOM   1162 O O   . PHE A 1 312 ? 120.899 93.153  93.266  1.00 35.39  ? 312 PHE A O   1 
ATOM   1163 C CB  . PHE A 1 312 ? 119.881 95.733  93.704  1.00 35.39  ? 312 PHE A CB  1 
ATOM   1164 C CG  . PHE A 1 312 ? 119.502 97.184  93.836  1.00 35.39  ? 312 PHE A CG  1 
ATOM   1165 C CD1 . PHE A 1 312 ? 120.473 98.170  93.891  1.00 35.39  ? 312 PHE A CD1 1 
ATOM   1166 C CD2 . PHE A 1 312 ? 118.171 97.560  93.925  1.00 35.39  ? 312 PHE A CD2 1 
ATOM   1167 C CE1 . PHE A 1 312 ? 120.125 99.502  94.020  1.00 35.39  ? 312 PHE A CE1 1 
ATOM   1168 C CE2 . PHE A 1 312 ? 117.818 98.891  94.055  1.00 35.39  ? 312 PHE A CE2 1 
ATOM   1169 C CZ  . PHE A 1 312 ? 118.797 99.862  94.102  1.00 35.39  ? 312 PHE A CZ  1 
ATOM   1170 N N   . PRO A 1 313 ? 122.599 93.907  92.016  1.00 34.95  ? 313 PRO A N   1 
ATOM   1171 C CA  . PRO A 1 313 ? 123.300 92.619  92.130  1.00 34.95  ? 313 PRO A CA  1 
ATOM   1172 C C   . PRO A 1 313 ? 123.592 92.218  93.561  1.00 34.95  ? 313 PRO A C   1 
ATOM   1173 O O   . PRO A 1 313 ? 123.701 91.021  93.852  1.00 34.95  ? 313 PRO A O   1 
ATOM   1174 C CB  . PRO A 1 313 ? 124.591 92.853  91.334  1.00 34.95  ? 313 PRO A CB  1 
ATOM   1175 C CG  . PRO A 1 313 ? 124.243 93.914  90.363  1.00 34.95  ? 313 PRO A CG  1 
ATOM   1176 C CD  . PRO A 1 313 ? 123.255 94.806  91.054  1.00 34.95  ? 313 PRO A CD  1 
ATOM   1177 N N   . GLU A 1 314 ? 123.590 93.175  94.488  1.00 35.71  ? 314 GLU A N   1 
ATOM   1178 C CA  . GLU A 1 314 ? 123.925 92.917  95.916  1.00 35.71  ? 314 GLU A CA  1 
ATOM   1179 C C   . GLU A 1 314 ? 122.748 92.308  96.689  1.00 35.71  ? 314 GLU A C   1 
ATOM   1180 O O   . GLU A 1 314 ? 122.914 92.124  97.908  1.00 35.71  ? 314 GLU A O   1 
ATOM   1181 C CB  . GLU A 1 314 ? 124.342 94.231  96.579  1.00 35.71  ? 314 GLU A CB  1 
ATOM   1182 C CG  . GLU A 1 314 ? 125.651 94.799  96.049  1.00 35.71  ? 314 GLU A CG  1 
ATOM   1183 C CD  . GLU A 1 314 ? 126.052 96.140  96.640  1.00 35.71  ? 314 GLU A CD  1 
ATOM   1184 O OE1 . GLU A 1 314 ? 125.221 96.748  97.340  1.00 35.71  ? 314 GLU A OE1 1 
ATOM   1185 O OE2 . GLU A 1 314 ? 127.197 96.570  96.402  1.00 35.71  ? 314 GLU A OE2 1 
ATOM   1186 N N   . PHE A 1 315 ? 121.616 91.999  96.049  1.00 36.66  ? 315 PHE A N   1 
ATOM   1187 C CA  . PHE A 1 315 ? 120.394 91.509  96.749  1.00 36.66  ? 315 PHE A CA  1 
ATOM   1188 C C   . PHE A 1 315 ? 120.167 90.018  96.491  1.00 36.66  ? 315 PHE A C   1 
ATOM   1189 O O   . PHE A 1 315 ? 119.005 89.579  96.599  1.00 36.66  ? 315 PHE A O   1 
ATOM   1190 C CB  . PHE A 1 315 ? 119.174 92.317  96.299  1.00 36.66  ? 315 PHE A CB  1 
ATOM   1191 C CG  . PHE A 1 315 ? 117.909 92.060  97.078  1.00 36.66  ? 315 PHE A CG  1 
ATOM   1192 C CD1 . PHE A 1 315 ? 117.925 91.973  98.461  1.00 36.66  ? 315 PHE A CD1 1 
ATOM   1193 C CD2 . PHE A 1 315 ? 116.699 91.904  96.422  1.00 36.66  ? 315 PHE A CD2 1 
ATOM   1194 C CE1 . PHE A 1 315 ? 116.757 91.736  99.170  1.00 36.66  ? 315 PHE A CE1 1 
ATOM   1195 C CE2 . PHE A 1 315 ? 115.533 91.668  97.132  1.00 36.66  ? 315 PHE A CE2 1 
ATOM   1196 C CZ  . PHE A 1 315 ? 115.564 91.588  98.504  1.00 36.66  ? 315 PHE A CZ  1 
ATOM   1197 N N   . ALA A 1 316 ? 121.218 89.261  96.164  1.00 40.15  ? 316 ALA A N   1 
ATOM   1198 C CA  . ALA A 1 316 ? 121.122 87.806  95.891  1.00 40.15  ? 316 ALA A CA  1 
ATOM   1199 C C   . ALA A 1 316 ? 121.562 87.012  97.123  1.00 40.15  ? 316 ALA A C   1 
ATOM   1200 O O   . ALA A 1 316 ? 121.189 85.828  97.208  1.00 40.15  ? 316 ALA A O   1 
ATOM   1201 C CB  . ALA A 1 316 ? 121.959 87.451  94.690  1.00 40.15  ? 316 ALA A CB  1 
ATOM   1202 N N   . ARG A 1 317 ? 122.329 87.623  98.030  1.00 40.54  ? 317 ARG A N   1 
ATOM   1203 C CA  . ARG A 1 317 ? 122.842 86.945  99.251  1.00 40.54  ? 317 ARG A CA  1 
ATOM   1204 C C   . ARG A 1 317 ? 122.250 87.605  100.497 1.00 40.54  ? 317 ARG A C   1 
ATOM   1205 O O   . ARG A 1 317 ? 122.555 87.127  101.605 1.00 40.54  ? 317 ARG A O   1 
ATOM   1206 C CB  . ARG A 1 317 ? 124.370 87.021  99.297  1.00 40.54  ? 317 ARG A CB  1 
ATOM   1207 N N   . TYR A 1 318 ? 121.443 88.655  100.335 1.00 35.99  ? 318 TYR A N   1 
ATOM   1208 C CA  . TYR A 1 318 ? 120.825 89.390  101.467 1.00 35.99  ? 318 TYR A CA  1 
ATOM   1209 C C   . TYR A 1 318 ? 120.000 88.415  102.305 1.00 35.99  ? 318 TYR A C   1 
ATOM   1210 O O   . TYR A 1 318 ? 119.233 87.642  101.706 1.00 35.99  ? 318 TYR A O   1 
ATOM   1211 C CB  . TYR A 1 318 ? 119.961 90.537  100.940 1.00 35.99  ? 318 TYR A CB  1 
ATOM   1212 C CG  . TYR A 1 318 ? 119.163 91.265  101.991 1.00 35.99  ? 318 TYR A CG  1 
ATOM   1213 C CD1 . TYR A 1 318 ? 118.017 90.710  102.534 1.00 35.99  ? 318 TYR A CD1 1 
ATOM   1214 C CD2 . TYR A 1 318 ? 119.550 92.517  102.437 1.00 35.99  ? 318 TYR A CD2 1 
ATOM   1215 C CE1 . TYR A 1 318 ? 117.279 91.376  103.498 1.00 35.99  ? 318 TYR A CE1 1 
ATOM   1216 C CE2 . TYR A 1 318 ? 118.824 93.196  103.401 1.00 35.99  ? 318 TYR A CE2 1 
ATOM   1217 C CZ  . TYR A 1 318 ? 117.683 92.624  103.932 1.00 35.99  ? 318 TYR A CZ  1 
ATOM   1218 O OH  . TYR A 1 318 ? 116.960 93.285  104.880 1.00 35.99  ? 318 TYR A OH  1 
ATOM   1219 N N   . THR A 1 319 ? 120.154 88.431  103.631 1.00 40.54  ? 319 THR A N   1 
ATOM   1220 C CA  . THR A 1 319 ? 119.378 87.566  104.561 1.00 40.54  ? 319 THR A CA  1 
ATOM   1221 C C   . THR A 1 319 ? 118.730 88.469  105.610 1.00 40.54  ? 319 THR A C   1 
ATOM   1222 O O   . THR A 1 319 ? 119.470 89.258  106.230 1.00 40.54  ? 319 THR A O   1 
ATOM   1223 C CB  . THR A 1 319 ? 120.263 86.480  105.188 1.00 40.54  ? 319 THR A CB  1 
ATOM   1224 O OG1 . THR A 1 319 ? 120.698 86.929  106.471 1.00 40.54  ? 319 THR A OG1 1 
ATOM   1225 C CG2 . THR A 1 319 ? 121.467 86.142  104.337 1.00 40.54  ? 319 THR A CG2 1 
ATOM   1226 N N   . THR A 1 320 ? 117.414 88.377  105.802 1.00 40.59  ? 320 THR A N   1 
ATOM   1227 C CA  . THR A 1 320 ? 116.682 89.264  106.742 1.00 40.59  ? 320 THR A CA  1 
ATOM   1228 C C   . THR A 1 320 ? 117.558 89.472  107.981 1.00 40.59  ? 320 THR A C   1 
ATOM   1229 O O   . THR A 1 320 ? 117.978 88.462  108.576 1.00 40.59  ? 320 THR A O   1 
ATOM   1230 C CB  . THR A 1 320 ? 115.305 88.692  107.095 1.00 40.59  ? 320 THR A CB  1 
ATOM   1231 O OG1 . THR A 1 320 ? 114.621 88.408  105.874 1.00 40.59  ? 320 THR A OG1 1 
ATOM   1232 C CG2 . THR A 1 320 ? 114.476 89.635  107.938 1.00 40.59  ? 320 THR A CG2 1 
ATOM   1233 N N   . PRO A 1 321 ? 117.867 90.724  108.386 1.00 46.68  ? 321 PRO A N   1 
ATOM   1234 C CA  . PRO A 1 321 ? 118.741 90.968  109.533 1.00 46.68  ? 321 PRO A CA  1 
ATOM   1235 C C   . PRO A 1 321 ? 118.160 90.210  110.733 1.00 46.68  ? 321 PRO A C   1 
ATOM   1236 O O   . PRO A 1 321 ? 116.956 90.036  110.754 1.00 46.68  ? 321 PRO A O   1 
ATOM   1237 C CB  . PRO A 1 321 ? 118.720 92.493  109.712 1.00 46.68  ? 321 PRO A CB  1 
ATOM   1238 C CG  . PRO A 1 321 ? 117.472 92.933  108.981 1.00 46.68  ? 321 PRO A CG  1 
ATOM   1239 C CD  . PRO A 1 321 ? 117.357 91.971  107.819 1.00 46.68  ? 321 PRO A CD  1 
ATOM   1240 N N   . GLU A 1 322 ? 118.987 89.776  111.689 1.00 63.89  ? 322 GLU A N   1 
ATOM   1241 C CA  . GLU A 1 322 ? 118.509 88.953  112.796 1.00 63.89  ? 322 GLU A CA  1 
ATOM   1242 C C   . GLU A 1 322 ? 117.515 89.713  113.663 1.00 63.89  ? 322 GLU A C   1 
ATOM   1243 O O   . GLU A 1 322 ? 116.506 89.149  114.104 1.00 63.89  ? 322 GLU A O   1 
ATOM   1244 C CB  . GLU A 1 322 ? 119.695 88.469  113.628 1.00 63.89  ? 322 GLU A CB  1 
ATOM   1245 N N   . ASP A 1 323 ? 117.775 90.992  113.915 1.00 64.82  ? 323 ASP A N   1 
ATOM   1246 C CA  . ASP A 1 323 ? 116.893 91.812  114.746 1.00 64.82  ? 323 ASP A CA  1 
ATOM   1247 C C   . ASP A 1 323 ? 115.608 92.220  114.031 1.00 64.82  ? 323 ASP A C   1 
ATOM   1248 O O   . ASP A 1 323 ? 114.890 93.088  114.548 1.00 64.82  ? 323 ASP A O   1 
ATOM   1249 C CB  . ASP A 1 323 ? 117.636 93.062  115.225 1.00 64.82  ? 323 ASP A CB  1 
ATOM   1250 C CG  . ASP A 1 323 ? 118.294 93.823  114.090 1.00 64.82  ? 323 ASP A CG  1 
ATOM   1251 O OD1 . ASP A 1 323 ? 118.479 93.232  113.006 1.00 64.82  ? 323 ASP A OD1 1 
ATOM   1252 O OD2 . ASP A 1 323 ? 118.627 95.011  114.281 1.00 64.82  ? 323 ASP A OD2 1 
ATOM   1253 N N   . ALA A 1 324 ? 115.295 91.633  112.878 1.00 56.01  ? 324 ALA A N   1 
ATOM   1254 C CA  . ALA A 1 324 ? 114.082 91.995  112.159 1.00 56.01  ? 324 ALA A CA  1 
ATOM   1255 C C   . ALA A 1 324 ? 112.852 91.738  113.020 1.00 56.01  ? 324 ALA A C   1 
ATOM   1256 O O   . ALA A 1 324 ? 112.811 90.790  113.808 1.00 56.01  ? 324 ALA A O   1 
ATOM   1257 C CB  . ALA A 1 324 ? 113.987 91.202  110.856 1.00 56.01  ? 324 ALA A CB  1 
ATOM   1258 N N   . THR A 1 325 ? 111.846 92.596  112.869 1.00 57.73  ? 325 THR A N   1 
ATOM   1259 C CA  . THR A 1 325 ? 110.593 92.501  113.615 1.00 57.73  ? 325 THR A CA  1 
ATOM   1260 C C   . THR A 1 325 ? 109.437 92.550  112.624 1.00 57.73  ? 325 THR A C   1 
ATOM   1261 O O   . THR A 1 325 ? 108.729 93.557  112.518 1.00 57.73  ? 325 THR A O   1 
ATOM   1262 C CB  . THR A 1 325 ? 110.484 93.623  114.648 1.00 57.73  ? 325 THR A CB  1 
ATOM   1263 N N   . PRO A 1 326 ? 109.224 91.473  111.873 1.00 59.73  ? 326 PRO A N   1 
ATOM   1264 C CA  . PRO A 1 326 ? 108.155 91.478  110.869 1.00 59.73  ? 326 PRO A CA  1 
ATOM   1265 C C   . PRO A 1 326 ? 106.778 91.575  111.502 1.00 59.73  ? 326 PRO A C   1 
ATOM   1266 O O   . PRO A 1 326 ? 106.543 91.108  112.619 1.00 59.73  ? 326 PRO A O   1 
ATOM   1267 C CB  . PRO A 1 326 ? 108.330 90.142  110.135 1.00 59.73  ? 326 PRO A CB  1 
ATOM   1268 C CG  . PRO A 1 326 ? 109.294 89.338  110.919 1.00 59.73  ? 326 PRO A CG  1 
ATOM   1269 C CD  . PRO A 1 326 ? 109.936 90.187  111.960 1.00 59.73  ? 326 PRO A CD  1 
ATOM   1270 N N   . GLU A 1 327 ? 105.862 92.195  110.765 1.00 69.31  ? 327 GLU A N   1 
ATOM   1271 C CA  . GLU A 1 327 ? 104.472 92.231  111.176 1.00 69.31  ? 327 GLU A CA  1 
ATOM   1272 C C   . GLU A 1 327 ? 103.850 90.845  111.022 1.00 69.31  ? 327 GLU A C   1 
ATOM   1273 O O   . GLU A 1 327 ? 104.330 90.022  110.240 1.00 69.31  ? 327 GLU A O   1 
ATOM   1274 C CB  . GLU A 1 327 ? 103.698 93.250  110.343 1.00 69.31  ? 327 GLU A CB  1 
ATOM   1275 N N   . PRO A 1 328 ? 102.779 90.561  111.762 1.00 72.49  ? 328 PRO A N   1 
ATOM   1276 C CA  . PRO A 1 328 ? 102.154 89.237  111.660 1.00 72.49  ? 328 PRO A CA  1 
ATOM   1277 C C   . PRO A 1 328 ? 101.620 88.973  110.260 1.00 72.49  ? 328 PRO A C   1 
ATOM   1278 O O   . PRO A 1 328 ? 101.171 89.881  109.557 1.00 72.49  ? 328 PRO A O   1 
ATOM   1279 C CB  . PRO A 1 328 ? 101.021 89.296  112.692 1.00 72.49  ? 328 PRO A CB  1 
ATOM   1280 C CG  . PRO A 1 328 ? 100.765 90.748  112.908 1.00 72.49  ? 328 PRO A CG  1 
ATOM   1281 C CD  . PRO A 1 328 ? 102.084 91.428  112.728 1.00 72.49  ? 328 PRO A CD  1 
ATOM   1282 N N   . GLY A 1 329 ? 101.676 87.704  109.859 1.00 68.72  ? 329 GLY A N   1 
ATOM   1283 C CA  . GLY A 1 329 ? 101.151 87.293  108.572 1.00 68.72  ? 329 GLY A CA  1 
ATOM   1284 C C   . GLY A 1 329 ? 101.839 87.953  107.396 1.00 68.72  ? 329 GLY A C   1 
ATOM   1285 O O   . GLY A 1 329 ? 101.173 88.472  106.495 1.00 68.72  ? 329 GLY A O   1 
ATOM   1286 N N   . GLU A 1 330 ? 103.170 87.944  107.390 1.00 60.25  ? 330 GLU A N   1 
ATOM   1287 C CA  . GLU A 1 330 ? 103.959 88.568  106.336 1.00 60.25  ? 330 GLU A CA  1 
ATOM   1288 C C   . GLU A 1 330 ? 104.770 87.512  105.598 1.00 60.25  ? 330 GLU A C   1 
ATOM   1289 O O   . GLU A 1 330 ? 105.419 86.668  106.225 1.00 60.25  ? 330 GLU A O   1 
ATOM   1290 C CB  . GLU A 1 330 ? 104.894 89.636  106.906 1.00 60.25  ? 330 GLU A CB  1 
ATOM   1291 N N   . ASP A 1 331 ? 104.727 87.566  104.274 1.00 49.18  ? 331 ASP A N   1 
ATOM   1292 C CA  . ASP A 1 331 ? 105.573 86.711  103.458 1.00 49.18  ? 331 ASP A CA  1 
ATOM   1293 C C   . ASP A 1 331 ? 107.036 87.082  103.687 1.00 49.18  ? 331 ASP A C   1 
ATOM   1294 O O   . ASP A 1 331 ? 107.386 88.268  103.603 1.00 49.18  ? 331 ASP A O   1 
ATOM   1295 C CB  . ASP A 1 331 ? 105.200 86.874  101.983 1.00 49.18  ? 331 ASP A CB  1 
ATOM   1296 C CG  . ASP A 1 331 ? 106.065 86.044  101.055 1.00 49.18  ? 331 ASP A CG  1 
ATOM   1297 O OD1 . ASP A 1 331 ? 106.940 85.301  101.539 1.00 49.18  ? 331 ASP A OD1 1 
ATOM   1298 O OD2 . ASP A 1 331 ? 105.866 86.138  99.827  1.00 49.18  ? 331 ASP A OD2 1 
ATOM   1299 N N   . PRO A 1 332 ? 107.917 86.119  103.975 1.00 47.50  ? 332 PRO A N   1 
ATOM   1300 C CA  . PRO A 1 332 ? 109.317 86.485  104.252 1.00 47.50  ? 332 PRO A CA  1 
ATOM   1301 C C   . PRO A 1 332 ? 109.982 87.273  103.137 1.00 47.50  ? 332 PRO A C   1 
ATOM   1302 O O   . PRO A 1 332 ? 110.827 88.127  103.425 1.00 47.50  ? 332 PRO A O   1 
ATOM   1303 C CB  . PRO A 1 332 ? 110.004 85.125  104.469 1.00 47.50  ? 332 PRO A CB  1 
ATOM   1304 C CG  . PRO A 1 332 ? 109.018 84.088  104.024 1.00 47.50  ? 332 PRO A CG  1 
ATOM   1305 C CD  . PRO A 1 332 ? 107.675 84.691  104.237 1.00 47.50  ? 332 PRO A CD  1 
ATOM   1306 N N   . ARG A 1 333 ? 109.638 87.015  101.873 1.00 44.91  ? 333 ARG A N   1 
ATOM   1307 C CA  . ARG A 1 333 ? 110.245 87.773  100.781 1.00 44.91  ? 333 ARG A CA  1 
ATOM   1308 C C   . ARG A 1 333 ? 109.885 89.250  100.869 1.00 44.91  ? 333 ARG A C   1 
ATOM   1309 O O   . ARG A 1 333 ? 110.730 90.122  100.628 1.00 44.91  ? 333 ARG A O   1 
ATOM   1310 C CB  . ARG A 1 333 ? 109.809 87.199  99.434  1.00 44.91  ? 333 ARG A CB  1 
ATOM   1311 C CG  . ARG A 1 333 ? 110.089 85.712  99.262  1.00 44.91  ? 333 ARG A CG  1 
ATOM   1312 C CD  . ARG A 1 333 ? 109.336 85.141  98.071  1.00 44.91  ? 333 ARG A CD  1 
ATOM   1313 N NE  . ARG A 1 333 ? 107.891 85.150  98.279  1.00 44.91  ? 333 ARG A NE  1 
ATOM   1314 C CZ  . ARG A 1 333 ? 106.989 85.321  97.321  1.00 44.91  ? 333 ARG A CZ  1 
ATOM   1315 N NH1 . ARG A 1 333 ? 107.341 85.503  96.059  1.00 44.91  ? 333 ARG A NH1 1 
ATOM   1316 N NH2 . ARG A 1 333 ? 105.698 85.310  97.639  1.00 44.91  ? 333 ARG A NH2 1 
ATOM   1317 N N   . VAL A 1 334 ? 108.629 89.552  101.204 1.00 42.55  ? 334 VAL A N   1 
ATOM   1318 C CA  . VAL A 1 334 ? 108.198 90.944  101.303 1.00 42.55  ? 334 VAL A CA  1 
ATOM   1319 C C   . VAL A 1 334 ? 109.037 91.679  102.338 1.00 42.55  ? 334 VAL A C   1 
ATOM   1320 O O   . VAL A 1 334 ? 109.594 92.752  102.070 1.00 42.55  ? 334 VAL A O   1 
ATOM   1321 C CB  . VAL A 1 334 ? 106.700 91.014  101.649 1.00 42.55  ? 334 VAL A CB  1 
ATOM   1322 C CG1 . VAL A 1 334 ? 106.322 92.413  102.106 1.00 42.55  ? 334 VAL A CG1 1 
ATOM   1323 C CG2 . VAL A 1 334 ? 105.858 90.581  100.462 1.00 42.55  ? 334 VAL A CG2 1 
ATOM   1324 N N   . THR A 1 335 ? 109.145 91.103  103.537 1.00 40.58  ? 335 THR A N   1 
ATOM   1325 C CA  . THR A 1 335 ? 109.910 91.738  104.602 1.00 40.58  ? 335 THR A CA  1 
ATOM   1326 C C   . THR A 1 335 ? 111.385 91.828  104.240 1.00 40.58  ? 335 THR A C   1 
ATOM   1327 O O   . THR A 1 335 ? 112.038 92.837  104.522 1.00 40.58  ? 335 THR A O   1 
ATOM   1328 C CB  . THR A 1 335 ? 109.723 90.966  105.905 1.00 40.58  ? 335 THR A CB  1 
ATOM   1329 O OG1 . THR A 1 335 ? 108.332 90.681  106.098 1.00 40.58  ? 335 THR A OG1 1 
ATOM   1330 C CG2 . THR A 1 335 ? 110.235 91.773  107.079 1.00 40.58  ? 335 THR A CG2 1 
ATOM   1331 N N   . ARG A 1 336 ? 111.901 90.771  103.605 1.00 36.58  ? 336 ARG A N   1 
ATOM   1332 C CA  . ARG A 1 336 ? 113.323 90.715  103.188 1.00 36.58  ? 336 ARG A CA  1 
ATOM   1333 C C   . ARG A 1 336 ? 113.617 91.902  102.268 1.00 36.58  ? 336 ARG A C   1 
ATOM   1334 O O   . ARG A 1 336 ? 114.599 92.620  102.540 1.00 36.58  ? 336 ARG A O   1 
ATOM   1335 C CB  . ARG A 1 336 ? 113.610 89.381  102.494 1.00 36.58  ? 336 ARG A CB  1 
ATOM   1336 C CG  . ARG A 1 336 ? 115.073 89.172  102.139 1.00 36.58  ? 336 ARG A CG  1 
ATOM   1337 C CD  . ARG A 1 336 ? 115.330 87.832  101.482 1.00 36.58  ? 336 ARG A CD  1 
ATOM   1338 N NE  . ARG A 1 336 ? 116.636 87.795  100.840 1.00 36.58  ? 336 ARG A NE  1 
ATOM   1339 C CZ  . ARG A 1 336 ? 116.907 88.261  99.624  1.00 36.58  ? 336 ARG A CZ  1 
ATOM   1340 N NH1 . ARG A 1 336 ? 115.958 88.805  98.881  1.00 36.58  ? 336 ARG A NH1 1 
ATOM   1341 N NH2 . ARG A 1 336 ? 118.135 88.175  99.146  1.00 36.58  ? 336 ARG A NH2 1 
ATOM   1342 N N   . ALA A 1 337 ? 112.809 92.108  101.223 1.00 33.22  ? 337 ALA A N   1 
ATOM   1343 C CA  . ALA A 1 337 ? 113.029 93.199  100.280 1.00 33.22  ? 337 ALA A CA  1 
ATOM   1344 C C   . ALA A 1 337 ? 112.832 94.553  100.948 1.00 33.22  ? 337 ALA A C   1 
ATOM   1345 O O   . ALA A 1 337 ? 113.615 95.486  100.726 1.00 33.22  ? 337 ALA A O   1 
ATOM   1346 C CB  . ALA A 1 337 ? 112.093 93.053  99.082  1.00 33.22  ? 337 ALA A CB  1 
ATOM   1347 N N   . LYS A 1 338 ? 111.784 94.684  101.761 1.00 31.25  ? 338 LYS A N   1 
ATOM   1348 C CA  . LYS A 1 338 ? 111.503 95.958  102.411 1.00 31.25  ? 338 LYS A CA  1 
ATOM   1349 C C   . LYS A 1 338 ? 112.672 96.391  103.288 1.00 31.25  ? 338 LYS A C   1 
ATOM   1350 O O   . LYS A 1 338 ? 113.145 97.536  103.211 1.00 31.25  ? 338 LYS A O   1 
ATOM   1351 C CB  . LYS A 1 338 ? 110.216 95.824  103.225 1.00 31.25  ? 338 LYS A CB  1 
ATOM   1352 C CG  . LYS A 1 338 ? 110.077 96.789  104.376 1.00 31.25  ? 338 LYS A CG  1 
ATOM   1353 C CD  . LYS A 1 338 ? 108.651 96.806  104.899 1.00 31.25  ? 338 LYS A CD  1 
ATOM   1354 C CE  . LYS A 1 338 ? 108.267 95.485  105.538 1.00 31.25  ? 338 LYS A CE  1 
ATOM   1355 N NZ  . LYS A 1 338 ? 106.905 95.533  106.132 1.00 31.25  ? 338 LYS A NZ  1 
ATOM   1356 N N   . TYR A 1 339 ? 113.165 95.452  104.092 1.00 31.17  ? 339 TYR A N   1 
ATOM   1357 C CA  . TYR A 1 339 ? 114.292 95.718  105.015 1.00 31.17  ? 339 TYR A CA  1 
ATOM   1358 C C   . TYR A 1 339 ? 115.533 96.010  104.173 1.00 31.17  ? 339 TYR A C   1 
ATOM   1359 O O   . TYR A 1 339 ? 116.344 96.843  104.610 1.00 31.17  ? 339 TYR A O   1 
ATOM   1360 C CB  . TYR A 1 339 ? 114.473 94.531  105.961 1.00 31.17  ? 339 TYR A CB  1 
ATOM   1361 C CG  . TYR A 1 339 ? 113.467 94.459  107.082 1.00 31.17  ? 339 TYR A CG  1 
ATOM   1362 C CD1 . TYR A 1 339 ? 112.121 94.704  106.864 1.00 31.17  ? 339 TYR A CD1 1 
ATOM   1363 C CD2 . TYR A 1 339 ? 113.863 94.144  108.370 1.00 31.17  ? 339 TYR A CD2 1 
ATOM   1364 C CE1 . TYR A 1 339 ? 111.198 94.640  107.893 1.00 31.17  ? 339 TYR A CE1 1 
ATOM   1365 C CE2 . TYR A 1 339 ? 112.952 94.077  109.410 1.00 31.17  ? 339 TYR A CE2 1 
ATOM   1366 C CZ  . TYR A 1 339 ? 111.614 94.325  109.172 1.00 31.17  ? 339 TYR A CZ  1 
ATOM   1367 O OH  . TYR A 1 339 ? 110.708 94.257  110.190 1.00 31.17  ? 339 TYR A OH  1 
ATOM   1368 N N   . PHE A 1 340 ? 115.671 95.368  103.009 1.00 29.24  ? 340 PHE A N   1 
ATOM   1369 C CA  . PHE A 1 340 ? 116.827 95.576  102.094 1.00 29.24  ? 340 PHE A CA  1 
ATOM   1370 C C   . PHE A 1 340 ? 116.826 97.032  101.630 1.00 29.24  ? 340 PHE A C   1 
ATOM   1371 O O   . PHE A 1 340 ? 117.889 97.669  101.696 1.00 29.24  ? 340 PHE A O   1 
ATOM   1372 C CB  . PHE A 1 340 ? 116.765 94.599  100.918 1.00 29.24  ? 340 PHE A CB  1 
ATOM   1373 C CG  . PHE A 1 340 ? 117.678 94.929  99.765  1.00 29.24  ? 340 PHE A CG  1 
ATOM   1374 C CD1 . PHE A 1 340 ? 119.041 95.083  99.959  1.00 29.24  ? 340 PHE A CD1 1 
ATOM   1375 C CD2 . PHE A 1 340 ? 117.174 95.074  98.483  1.00 29.24  ? 340 PHE A CD2 1 
ATOM   1376 C CE1 . PHE A 1 340 ? 119.878 95.382  98.896  1.00 29.24  ? 340 PHE A CE1 1 
ATOM   1377 C CE2 . PHE A 1 340 ? 118.013 95.374  97.421  1.00 29.24  ? 340 PHE A CE2 1 
ATOM   1378 C CZ  . PHE A 1 340 ? 119.363 95.530  97.630  1.00 29.24  ? 340 PHE A CZ  1 
ATOM   1379 N N   . ILE A 1 341 ? 115.676 97.544  101.187 1.00 26.42  ? 341 ILE A N   1 
ATOM   1380 C CA  . ILE A 1 341 ? 115.545 98.927  100.741 1.00 26.42  ? 341 ILE A CA  1 
ATOM   1381 C C   . ILE A 1 341 ? 115.877 99.873  101.886 1.00 26.42  ? 341 ILE A C   1 
ATOM   1382 O O   . ILE A 1 341 ? 116.628 100.840 101.717 1.00 26.42  ? 341 ILE A O   1 
ATOM   1383 C CB  . ILE A 1 341 ? 114.135 99.190  100.184 1.00 26.42  ? 341 ILE A CB  1 
ATOM   1384 C CG1 . ILE A 1 341 ? 113.798 98.205  99.063  1.00 26.42  ? 341 ILE A CG1 1 
ATOM   1385 C CG2 . ILE A 1 341 ? 114.030 100.613 99.673  1.00 26.42  ? 341 ILE A CG2 1 
ATOM   1386 C CD1 . ILE A 1 341 ? 114.865 98.081  98.002  1.00 26.42  ? 341 ILE A CD1 1 
ATOM   1387 N N   . ARG A 1 342 ? 115.336 99.599  103.075 1.00 22.90  ? 342 ARG A N   1 
ATOM   1388 C CA  . ARG A 1 342 ? 115.679 100.427 104.230 1.00 22.90  ? 342 ARG A CA  1 
ATOM   1389 C C   . ARG A 1 342 ? 117.176 100.383 104.515 1.00 22.90  ? 342 ARG A C   1 
ATOM   1390 O O   . ARG A 1 342 ? 117.782 101.403 104.871 1.00 22.90  ? 342 ARG A O   1 
ATOM   1391 C CB  . ARG A 1 342 ? 114.894 99.974  105.458 1.00 22.90  ? 342 ARG A CB  1 
ATOM   1392 C CG  . ARG A 1 342 ? 114.989 100.937 106.630 1.00 22.90  ? 342 ARG A CG  1 
ATOM   1393 C CD  . ARG A 1 342 ? 114.752 100.241 107.954 1.00 22.90  ? 342 ARG A CD  1 
ATOM   1394 N NE  . ARG A 1 342 ? 115.872 99.390  108.333 1.00 22.90  ? 342 ARG A NE  1 
ATOM   1395 C CZ  . ARG A 1 342 ? 116.014 98.826  109.522 1.00 22.90  ? 342 ARG A CZ  1 
ATOM   1396 N NH1 . ARG A 1 342 ? 115.117 98.996  110.480 1.00 22.90  ? 342 ARG A NH1 1 
ATOM   1397 N NH2 . ARG A 1 342 ? 117.082 98.069  109.758 1.00 22.90  ? 342 ARG A NH2 1 
ATOM   1398 N N   . ASP A 1 343 ? 117.751 99.184  104.372 1.00 21.59  ? 343 ASP A N   1 
ATOM   1399 C CA  . ASP A 1 343 ? 119.181 98.934  104.684 1.00 21.59  ? 343 ASP A CA  1 
ATOM   1400 C C   . ASP A 1 343 ? 120.100 99.765  103.790 1.00 21.59  ? 343 ASP A C   1 
ATOM   1401 O O   . ASP A 1 343 ? 121.187 100.122 104.268 1.00 21.59  ? 343 ASP A O   1 
ATOM   1402 C CB  . ASP A 1 343 ? 119.532 97.454  104.518 1.00 21.59  ? 343 ASP A CB  1 
ATOM   1403 C CG  . ASP A 1 343 ? 120.754 97.213  103.650 1.00 21.59  ? 343 ASP A CG  1 
ATOM   1404 O OD1 . ASP A 1 343 ? 121.869 97.183  104.204 1.00 21.59  ? 343 ASP A OD1 1 
ATOM   1405 O OD2 . ASP A 1 343 ? 120.580 97.060  102.425 1.00 21.59  ? 343 ASP A OD2 1 
ATOM   1406 N N   . GLU A 1 344 ? 119.717 100.025 102.538 1.00 19.77  ? 344 GLU A N   1 
ATOM   1407 C CA  . GLU A 1 344 ? 120.547 100.847 101.656 1.00 19.77  ? 344 GLU A CA  1 
ATOM   1408 C C   . GLU A 1 344 ? 120.722 102.255 102.227 1.00 19.77  ? 344 GLU A C   1 
ATOM   1409 O O   . GLU A 1 344 ? 121.846 102.758 102.393 1.00 19.77  ? 344 GLU A O   1 
ATOM   1410 C CB  . GLU A 1 344 ? 119.926 100.909 100.260 1.00 19.77  ? 344 GLU A CB  1 
ATOM   1411 C CG  . GLU A 1 344 ? 119.695 99.558  99.610  1.00 19.77  ? 344 GLU A CG  1 
ATOM   1412 C CD  . GLU A 1 344 ? 120.868 99.114  98.766  1.00 19.77  ? 344 GLU A CD  1 
ATOM   1413 O OE1 . GLU A 1 344 ? 122.022 99.311  99.201  1.00 19.77  ? 344 GLU A OE1 1 
ATOM   1414 O OE2 . GLU A 1 344 ? 120.637 98.570  97.668  1.00 19.77  ? 344 GLU A OE2 1 
ATOM   1415 N N   . PHE A 1 345 ? 119.601 102.900 102.550 1.00 16.38  ? 345 PHE A N   1 
ATOM   1416 C CA  . PHE A 1 345 ? 119.656 104.240 103.117 1.00 16.38  ? 345 PHE A CA  1 
ATOM   1417 C C   . PHE A 1 345 ? 120.352 104.232 104.469 1.00 16.38  ? 345 PHE A C   1 
ATOM   1418 O O   . PHE A 1 345 ? 121.127 105.140 104.784 1.00 16.38  ? 345 PHE A O   1 
ATOM   1419 C CB  . PHE A 1 345 ? 118.247 104.816 103.232 1.00 16.38  ? 345 PHE A CB  1 
ATOM   1420 C CG  . PHE A 1 345 ? 117.635 105.167 101.907 1.00 16.38  ? 345 PHE A CG  1 
ATOM   1421 C CD1 . PHE A 1 345 ? 117.093 104.187 101.096 1.00 16.38  ? 345 PHE A CD1 1 
ATOM   1422 C CD2 . PHE A 1 345 ? 117.613 106.477 101.468 1.00 16.38  ? 345 PHE A CD2 1 
ATOM   1423 C CE1 . PHE A 1 345 ? 116.533 104.509 99.880  1.00 16.38  ? 345 PHE A CE1 1 
ATOM   1424 C CE2 . PHE A 1 345 ? 117.055 106.801 100.255 1.00 16.38  ? 345 PHE A CE2 1 
ATOM   1425 C CZ  . PHE A 1 345 ? 116.514 105.817 99.460  1.00 16.38  ? 345 PHE A CZ  1 
ATOM   1426 N N   . LEU A 1 346 ? 120.086 103.215 105.293 1.00 19.52  ? 346 LEU A N   1 
ATOM   1427 C CA  . LEU A 1 346 ? 120.754 103.148 106.588 1.00 19.52  ? 346 LEU A CA  1 
ATOM   1428 C C   . LEU A 1 346 ? 122.251 102.897 106.456 1.00 19.52  ? 346 LEU A C   1 
ATOM   1429 O O   . LEU A 1 346 ? 123.001 103.211 107.384 1.00 19.52  ? 346 LEU A O   1 
ATOM   1430 C CB  . LEU A 1 346 ? 120.119 102.063 107.457 1.00 19.52  ? 346 LEU A CB  1 
ATOM   1431 C CG  . LEU A 1 346 ? 118.875 102.500 108.234 1.00 19.52  ? 346 LEU A CG  1 
ATOM   1432 C CD1 . LEU A 1 346 ? 118.180 101.301 108.847 1.00 19.52  ? 346 LEU A CD1 1 
ATOM   1433 C CD2 . LEU A 1 346 ? 119.238 103.508 109.307 1.00 19.52  ? 346 LEU A CD2 1 
ATOM   1434 N N   . ARG A 1 347 ? 122.702 102.331 105.337 1.00 17.93  ? 347 ARG A N   1 
ATOM   1435 C CA  . ARG A 1 347 ? 124.134 102.196 105.105 1.00 17.93  ? 347 ARG A CA  1 
ATOM   1436 C C   . ARG A 1 347 ? 124.739 103.528 104.701 1.00 17.93  ? 347 ARG A C   1 
ATOM   1437 O O   . ARG A 1 347 ? 125.858 103.860 105.108 1.00 17.93  ? 347 ARG A O   1 
ATOM   1438 C CB  . ARG A 1 347 ? 124.410 101.152 104.024 1.00 17.93  ? 347 ARG A CB  1 
ATOM   1439 C CG  . ARG A 1 347 ? 125.891 100.838 103.840 1.00 17.93  ? 347 ARG A CG  1 
ATOM   1440 C CD  . ARG A 1 347 ? 126.195 100.257 102.469 1.00 17.93  ? 347 ARG A CD  1 
ATOM   1441 N NE  . ARG A 1 347 ? 125.313 99.147  102.128 1.00 17.93  ? 347 ARG A NE  1 
ATOM   1442 C CZ  . ARG A 1 347 ? 124.232 99.243  101.365 1.00 17.93  ? 347 ARG A CZ  1 
ATOM   1443 N NH1 . ARG A 1 347 ? 123.861 100.394 100.827 1.00 17.93  ? 347 ARG A NH1 1 
ATOM   1444 N NH2 . ARG A 1 347 ? 123.502 98.156  101.135 1.00 17.93  ? 347 ARG A NH2 1 
ATOM   1445 N N   . ILE A 1 348 ? 124.018 104.300 103.888 1.00 17.04  ? 348 ILE A N   1 
ATOM   1446 C CA  . ILE A 1 348 ? 124.500 105.643 103.562 1.00 17.04  ? 348 ILE A CA  1 
ATOM   1447 C C   . ILE A 1 348 ? 124.582 106.489 104.828 1.00 17.04  ? 348 ILE A C   1 
ATOM   1448 O O   . ILE A 1 348 ? 125.561 107.208 105.056 1.00 17.04  ? 348 ILE A O   1 
ATOM   1449 C CB  . ILE A 1 348 ? 123.602 106.306 102.503 1.00 17.04  ? 348 ILE A CB  1 
ATOM   1450 C CG1 . ILE A 1 348 ? 123.965 105.796 101.112 1.00 17.04  ? 348 ILE A CG1 1 
ATOM   1451 C CG2 . ILE A 1 348 ? 123.762 107.816 102.539 1.00 17.04  ? 348 ILE A CG2 1 
ATOM   1452 C CD1 . ILE A 1 348 ? 122.892 106.022 100.088 1.00 17.04  ? 348 ILE A CD1 1 
ATOM   1453 N N   . SER A 1 349 ? 123.552 106.409 105.672 1.00 17.80  ? 349 SER A N   1 
ATOM   1454 C CA  . SER A 1 349 ? 123.444 107.308 106.817 1.00 17.80  ? 349 SER A CA  1 
ATOM   1455 C C   . SER A 1 349 ? 124.557 107.066 107.830 1.00 17.80  ? 349 SER A C   1 
ATOM   1456 O O   . SER A 1 349 ? 125.152 108.016 108.352 1.00 17.80  ? 349 SER A O   1 
ATOM   1457 C CB  . SER A 1 349 ? 122.076 107.141 107.477 1.00 17.80  ? 349 SER A CB  1 
ATOM   1458 O OG  . SER A 1 349 ? 122.103 106.123 108.457 1.00 17.80  ? 349 SER A OG  1 
ATOM   1459 N N   . THR A 1 350 ? 124.856 105.802 108.123 1.00 20.06  ? 350 THR A N   1 
ATOM   1460 C CA  . THR A 1 350 ? 125.777 105.455 109.200 1.00 20.06  ? 350 THR A CA  1 
ATOM   1461 C C   . THR A 1 350 ? 127.237 105.502 108.777 1.00 20.06  ? 350 THR A C   1 
ATOM   1462 O O   . THR A 1 350 ? 128.070 104.850 109.417 1.00 20.06  ? 350 THR A O   1 
ATOM   1463 C CB  . THR A 1 350 ? 125.449 104.064 109.751 1.00 20.06  ? 350 THR A CB  1 
ATOM   1464 O OG1 . THR A 1 350 ? 125.628 103.084 108.722 1.00 20.06  ? 350 THR A OG1 1 
ATOM   1465 C CG2 . THR A 1 350 ? 124.021 104.009 110.268 1.00 20.06  ? 350 THR A CG2 1 
ATOM   1466 N N   . ALA A 1 351 ? 127.570 106.237 107.722 1.00 28.74  ? 351 ALA A N   1 
ATOM   1467 C CA  . ALA A 1 351 ? 128.952 106.447 107.312 1.00 28.74  ? 351 ALA A CA  1 
ATOM   1468 C C   . ALA A 1 351 ? 129.266 107.932 107.418 1.00 28.74  ? 351 ALA A C   1 
ATOM   1469 O O   . ALA A 1 351 ? 128.639 108.752 106.740 1.00 28.74  ? 351 ALA A O   1 
ATOM   1470 C CB  . ALA A 1 351 ? 129.189 105.944 105.888 1.00 28.74  ? 351 ALA A CB  1 
ATOM   1471 N N   . SER A 1 352 ? 130.237 108.273 108.263 1.00 34.38  ? 352 SER A N   1 
ATOM   1472 C CA  . SER A 1 352 ? 130.643 109.664 108.460 1.00 34.38  ? 352 SER A CA  1 
ATOM   1473 C C   . SER A 1 352 ? 129.528 110.489 109.099 1.00 34.38  ? 352 SER A C   1 
ATOM   1474 O O   . SER A 1 352 ? 129.482 111.713 108.955 1.00 34.38  ? 352 SER A O   1 
ATOM   1475 C CB  . SER A 1 352 ? 131.082 110.295 107.138 1.00 34.38  ? 352 SER A CB  1 
ATOM   1476 O OG  . SER A 1 352 ? 129.969 110.527 106.293 1.00 34.38  ? 352 SER A OG  1 
ATOM   1477 N N   . GLY A 1 353 ? 128.616 109.824 109.809 1.00 41.19  ? 353 GLY A N   1 
ATOM   1478 C CA  . GLY A 1 353 ? 127.584 110.556 110.529 1.00 41.19  ? 353 GLY A CA  1 
ATOM   1479 C C   . GLY A 1 353 ? 128.161 111.431 111.624 1.00 41.19  ? 353 GLY A C   1 
ATOM   1480 O O   . GLY A 1 353 ? 127.787 112.597 111.769 1.00 41.19  ? 353 GLY A O   1 
ATOM   1481 N N   . ASP A 1 354 ? 129.077 110.875 112.417 1.00 46.68  ? 354 ASP A N   1 
ATOM   1482 C CA  . ASP A 1 354 ? 129.849 111.604 113.420 1.00 46.68  ? 354 ASP A CA  1 
ATOM   1483 C C   . ASP A 1 354 ? 129.014 112.039 114.620 1.00 46.68  ? 354 ASP A C   1 
ATOM   1484 O O   . ASP A 1 354 ? 129.433 112.920 115.376 1.00 46.68  ? 354 ASP A O   1 
ATOM   1485 C CB  . ASP A 1 354 ? 130.533 112.826 112.801 1.00 46.68  ? 354 ASP A CB  1 
ATOM   1486 C CG  . ASP A 1 354 ? 131.414 112.465 111.620 1.00 46.68  ? 354 ASP A CG  1 
ATOM   1487 O OD1 . ASP A 1 354 ? 131.953 111.339 111.601 1.00 46.68  ? 354 ASP A OD1 1 
ATOM   1488 O OD2 . ASP A 1 354 ? 131.566 113.307 110.710 1.00 46.68  ? 354 ASP A OD2 1 
ATOM   1489 N N   . GLY A 1 355 ? 127.839 111.447 114.816 1.00 42.43  ? 355 GLY A N   1 
ATOM   1490 C CA  . GLY A 1 355 ? 127.054 111.698 116.011 1.00 42.43  ? 355 GLY A CA  1 
ATOM   1491 C C   . GLY A 1 355 ? 126.649 113.145 116.206 1.00 42.43  ? 355 GLY A C   1 
ATOM   1492 O O   . GLY A 1 355 ? 126.716 113.667 117.323 1.00 42.43  ? 355 GLY A O   1 
ATOM   1493 N N   . ARG A 1 356 ? 126.225 113.803 115.127 1.00 33.50  ? 356 ARG A N   1 
ATOM   1494 C CA  . ARG A 1 356 ? 125.710 115.166 115.194 1.00 33.50  ? 356 ARG A CA  1 
ATOM   1495 C C   . ARG A 1 356 ? 124.362 115.345 114.512 1.00 33.50  ? 356 ARG A C   1 
ATOM   1496 O O   . ARG A 1 356 ? 123.640 116.284 114.863 1.00 33.50  ? 356 ARG A O   1 
ATOM   1497 C CB  . ARG A 1 356 ? 126.716 116.147 114.573 1.00 33.50  ? 356 ARG A CB  1 
ATOM   1498 C CG  . ARG A 1 356 ? 127.096 115.806 113.148 1.00 33.50  ? 356 ARG A CG  1 
ATOM   1499 C CD  . ARG A 1 356 ? 128.240 116.662 112.644 1.00 33.50  ? 356 ARG A CD  1 
ATOM   1500 N NE  . ARG A 1 356 ? 128.712 116.210 111.340 1.00 33.50  ? 356 ARG A NE  1 
ATOM   1501 C CZ  . ARG A 1 356 ? 129.933 115.762 111.079 1.00 33.50  ? 356 ARG A CZ  1 
ATOM   1502 N NH1 . ARG A 1 356 ? 130.876 115.725 112.009 1.00 33.50  ? 356 ARG A NH1 1 
ATOM   1503 N NH2 . ARG A 1 356 ? 130.221 115.342 109.851 1.00 33.50  ? 356 ARG A NH2 1 
ATOM   1504 N N   . HIS A 1 357 ? 124.000 114.488 113.561 1.00 22.21  ? 357 HIS A N   1 
ATOM   1505 C CA  . HIS A 1 357 ? 122.666 114.454 112.984 1.00 22.21  ? 357 HIS A CA  1 
ATOM   1506 C C   . HIS A 1 357 ? 122.330 113.001 112.694 1.00 22.21  ? 357 HIS A C   1 
ATOM   1507 O O   . HIS A 1 357 ? 123.225 112.175 112.497 1.00 22.21  ? 357 HIS A O   1 
ATOM   1508 C CB  . HIS A 1 357 ? 122.580 115.306 111.714 1.00 22.21  ? 357 HIS A CB  1 
ATOM   1509 C CG  . HIS A 1 357 ? 123.484 114.848 110.615 1.00 22.21  ? 357 HIS A CG  1 
ATOM   1510 N ND1 . HIS A 1 357 ? 123.080 113.975 109.630 1.00 22.21  ? 357 HIS A ND1 1 
ATOM   1511 C CD2 . HIS A 1 357 ? 124.784 115.126 110.358 1.00 22.21  ? 357 HIS A CD2 1 
ATOM   1512 C CE1 . HIS A 1 357 ? 124.087 113.751 108.805 1.00 22.21  ? 357 HIS A CE1 1 
ATOM   1513 N NE2 . HIS A 1 357 ? 125.133 114.435 109.227 1.00 22.21  ? 357 HIS A NE2 1 
ATOM   1514 N N   . TYR A 1 358 ? 121.038 112.686 112.675 1.00 21.09  ? 358 TYR A N   1 
ATOM   1515 C CA  . TYR A 1 358 ? 120.595 111.299 112.686 1.00 21.09  ? 358 TYR A CA  1 
ATOM   1516 C C   . TYR A 1 358 ? 119.565 111.063 111.589 1.00 21.09  ? 358 TYR A C   1 
ATOM   1517 O O   . TYR A 1 358 ? 119.247 111.950 110.793 1.00 21.09  ? 358 TYR A O   1 
ATOM   1518 C CB  . TYR A 1 358 ? 120.024 110.924 114.058 1.00 21.09  ? 358 TYR A CB  1 
ATOM   1519 C CG  . TYR A 1 358 ? 120.990 111.166 115.193 1.00 21.09  ? 358 TYR A CG  1 
ATOM   1520 C CD1 . TYR A 1 358 ? 121.182 112.441 115.705 1.00 21.09  ? 358 TYR A CD1 1 
ATOM   1521 C CD2 . TYR A 1 358 ? 121.717 110.123 115.746 1.00 21.09  ? 358 TYR A CD2 1 
ATOM   1522 C CE1 . TYR A 1 358 ? 122.067 112.670 116.737 1.00 21.09  ? 358 TYR A CE1 1 
ATOM   1523 C CE2 . TYR A 1 358 ? 122.606 110.341 116.780 1.00 21.09  ? 358 TYR A CE2 1 
ATOM   1524 C CZ  . TYR A 1 358 ? 122.775 111.618 117.271 1.00 21.09  ? 358 TYR A CZ  1 
ATOM   1525 O OH  . TYR A 1 358 ? 123.657 111.843 118.301 1.00 21.09  ? 358 TYR A OH  1 
ATOM   1526 N N   . CYS A 1 359 ? 119.057 109.833 111.554 1.00 18.37  ? 359 CYS A N   1 
ATOM   1527 C CA  . CYS A 1 359 ? 118.042 109.415 110.598 1.00 18.37  ? 359 CYS A CA  1 
ATOM   1528 C C   . CYS A 1 359 ? 117.121 108.428 111.297 1.00 18.37  ? 359 CYS A C   1 
ATOM   1529 O O   . CYS A 1 359 ? 117.581 107.594 112.080 1.00 18.37  ? 359 CYS A O   1 
ATOM   1530 C CB  . CYS A 1 359 ? 118.670 108.775 109.355 1.00 18.37  ? 359 CYS A CB  1 
ATOM   1531 S SG  . CYS A 1 359 ? 117.495 108.390 108.042 1.00 18.37  ? 359 CYS A SG  1 
ATOM   1532 N N   . TYR A 1 360 ? 115.825 108.522 111.011 1.00 16.60  ? 360 TYR A N   1 
ATOM   1533 C CA  . TYR A 1 360 ? 114.797 107.756 111.714 1.00 16.60  ? 360 TYR A CA  1 
ATOM   1534 C C   . TYR A 1 360 ? 113.923 107.040 110.695 1.00 16.60  ? 360 TYR A C   1 
ATOM   1535 O O   . TYR A 1 360 ? 112.811 107.489 110.392 1.00 16.60  ? 360 TYR A O   1 
ATOM   1536 C CB  . TYR A 1 360 ? 113.951 108.662 112.610 1.00 16.60  ? 360 TYR A CB  1 
ATOM   1537 C CG  . TYR A 1 360 ? 114.736 109.380 113.684 1.00 16.60  ? 360 TYR A CG  1 
ATOM   1538 C CD1 . TYR A 1 360 ? 115.657 110.365 113.358 1.00 16.60  ? 360 TYR A CD1 1 
ATOM   1539 C CD2 . TYR A 1 360 ? 114.554 109.076 115.024 1.00 16.60  ? 360 TYR A CD2 1 
ATOM   1540 C CE1 . TYR A 1 360 ? 116.374 111.021 114.334 1.00 16.60  ? 360 TYR A CE1 1 
ATOM   1541 C CE2 . TYR A 1 360 ? 115.268 109.728 116.006 1.00 16.60  ? 360 TYR A CE2 1 
ATOM   1542 C CZ  . TYR A 1 360 ? 116.176 110.699 115.654 1.00 16.60  ? 360 TYR A CZ  1 
ATOM   1543 O OH  . TYR A 1 360 ? 116.892 111.351 116.628 1.00 16.60  ? 360 TYR A OH  1 
ATOM   1544 N N   . PRO A 1 361 ? 114.389 105.917 110.150 1.00 16.24  ? 361 PRO A N   1 
ATOM   1545 C CA  . PRO A 1 361 ? 113.570 105.186 109.177 1.00 16.24  ? 361 PRO A CA  1 
ATOM   1546 C C   . PRO A 1 361 ? 112.231 104.774 109.768 1.00 16.24  ? 361 PRO A C   1 
ATOM   1547 O O   . PRO A 1 361 ? 112.134 104.401 110.938 1.00 16.24  ? 361 PRO A O   1 
ATOM   1548 C CB  . PRO A 1 361 ? 114.432 103.968 108.823 1.00 16.24  ? 361 PRO A CB  1 
ATOM   1549 C CG  . PRO A 1 361 ? 115.506 103.917 109.850 1.00 16.24  ? 361 PRO A CG  1 
ATOM   1550 C CD  . PRO A 1 361 ? 115.715 105.309 110.321 1.00 16.24  ? 361 PRO A CD  1 
ATOM   1551 N N   . HIS A 1 362 ? 111.191 104.842 108.939 1.00 19.68  ? 362 HIS A N   1 
ATOM   1552 C CA  . HIS A 1 362 ? 109.830 104.551 109.382 1.00 19.68  ? 362 HIS A CA  1 
ATOM   1553 C C   . HIS A 1 362 ? 109.020 104.103 108.176 1.00 19.68  ? 362 HIS A C   1 
ATOM   1554 O O   . HIS A 1 362 ? 108.646 104.933 107.344 1.00 19.68  ? 362 HIS A O   1 
ATOM   1555 C CB  . HIS A 1 362 ? 109.191 105.777 110.025 1.00 19.68  ? 362 HIS A CB  1 
ATOM   1556 C CG  . HIS A 1 362 ? 109.636 106.033 111.430 1.00 19.68  ? 362 HIS A CG  1 
ATOM   1557 N ND1 . HIS A 1 362 ? 109.445 105.125 112.448 1.00 19.68  ? 362 HIS A ND1 1 
ATOM   1558 C CD2 . HIS A 1 362 ? 110.242 107.105 111.991 1.00 19.68  ? 362 HIS A CD2 1 
ATOM   1559 C CE1 . HIS A 1 362 ? 109.925 105.622 113.574 1.00 19.68  ? 362 HIS A CE1 1 
ATOM   1560 N NE2 . HIS A 1 362 ? 110.414 106.822 113.324 1.00 19.68  ? 362 HIS A NE2 1 
ATOM   1561 N N   . PHE A 1 363 ? 108.742 102.805 108.079 1.00 24.86  ? 363 PHE A N   1 
ATOM   1562 C CA  . PHE A 1 363 ? 107.847 102.323 107.036 1.00 24.86  ? 363 PHE A CA  1 
ATOM   1563 C C   . PHE A 1 363 ? 106.460 102.913 107.240 1.00 24.86  ? 363 PHE A C   1 
ATOM   1564 O O   . PHE A 1 363 ? 105.951 102.964 108.363 1.00 24.86  ? 363 PHE A O   1 
ATOM   1565 C CB  . PHE A 1 363 ? 107.770 100.797 107.049 1.00 24.86  ? 363 PHE A CB  1 
ATOM   1566 C CG  . PHE A 1 363 ? 109.108 100.122 107.040 1.00 24.86  ? 363 PHE A CG  1 
ATOM   1567 C CD1 . PHE A 1 363 ? 109.868 100.083 105.892 1.00 24.86  ? 363 PHE A CD1 1 
ATOM   1568 C CD2 . PHE A 1 363 ? 109.599 99.522  108.182 1.00 24.86  ? 363 PHE A CD2 1 
ATOM   1569 C CE1 . PHE A 1 363 ? 111.095 99.466  105.886 1.00 24.86  ? 363 PHE A CE1 1 
ATOM   1570 C CE2 . PHE A 1 363 ? 110.824 98.904  108.177 1.00 24.86  ? 363 PHE A CE2 1 
ATOM   1571 C CZ  . PHE A 1 363 ? 111.571 98.874  107.027 1.00 24.86  ? 363 PHE A CZ  1 
ATOM   1572 N N   . THR A 1 364 ? 105.843 103.356 106.148 1.00 26.50  ? 364 THR A N   1 
ATOM   1573 C CA  . THR A 1 364 ? 104.554 104.023 106.241 1.00 26.50  ? 364 THR A CA  1 
ATOM   1574 C C   . THR A 1 364 ? 103.740 103.757 104.986 1.00 26.50  ? 364 THR A C   1 
ATOM   1575 O O   . THR A 1 364 ? 104.280 103.437 103.925 0.00 26.50  ? 364 THR A O   1 
ATOM   1576 C CB  . THR A 1 364 ? 104.717 105.535 106.439 1.00 26.50  ? 364 THR A CB  1 
ATOM   1577 O OG1 . THR A 1 364 ? 103.425 106.149 106.529 1.00 26.50  ? 364 THR A OG1 1 
ATOM   1578 C CG2 . THR A 1 364 ? 105.488 106.151 105.280 1.00 26.50  ? 364 THR A CG2 1 
ATOM   1579 N N   . CYS A 1 365 ? 102.427 103.889 105.130 1.00 35.29  ? 365 CYS A N   1 
ATOM   1580 C CA  . CYS A 1 365 ? 101.516 103.922 103.998 1.00 35.29  ? 365 CYS A CA  1 
ATOM   1581 C C   . CYS A 1 365 ? 101.287 105.380 103.607 1.00 35.29  ? 365 CYS A C   1 
ATOM   1582 O O   . CYS A 1 365 ? 101.986 106.285 104.070 1.00 35.29  ? 365 CYS A O   1 
ATOM   1583 C CB  . CYS A 1 365 ? 100.214 103.206 104.343 1.00 35.29  ? 365 CYS A CB  1 
ATOM   1584 S SG  . CYS A 1 365 ? 99.168  102.845 102.916 1.00 35.29  ? 365 CYS A SG  1 
ATOM   1585 N N   . ALA A 1 366 ? 100.304 105.630 102.746 1.00 42.46  ? 366 ALA A N   1 
ATOM   1586 C CA  . ALA A 1 366 ? 99.984  106.983 102.316 1.00 42.46  ? 366 ALA A CA  1 
ATOM   1587 C C   . ALA A 1 366 ? 98.866  107.625 103.126 1.00 42.46  ? 366 ALA A C   1 
ATOM   1588 O O   . ALA A 1 366 ? 98.690  108.845 103.047 1.00 42.46  ? 366 ALA A O   1 
ATOM   1589 C CB  . ALA A 1 366 ? 99.598  106.989 100.833 1.00 42.46  ? 366 ALA A CB  1 
ATOM   1590 N N   . VAL A 1 367 ? 98.110  106.844 103.898 1.00 44.79  ? 367 VAL A N   1 
ATOM   1591 C CA  . VAL A 1 367 ? 96.999  107.377 104.679 1.00 44.79  ? 367 VAL A CA  1 
ATOM   1592 C C   . VAL A 1 367 ? 97.097  106.905 106.124 1.00 44.79  ? 367 VAL A C   1 
ATOM   1593 O O   . VAL A 1 367 ? 96.098  106.890 106.850 1.00 44.79  ? 367 VAL A O   1 
ATOM   1594 C CB  . VAL A 1 367 ? 95.648  106.967 104.063 1.00 44.79  ? 367 VAL A CB  1 
ATOM   1595 C CG1 . VAL A 1 367 ? 95.561  107.438 102.623 1.00 44.79  ? 367 VAL A CG1 1 
ATOM   1596 C CG2 . VAL A 1 367 ? 95.458  105.462 104.146 1.00 44.79  ? 367 VAL A CG2 1 
ATOM   1597 N N   . ASP A 1 368 ? 98.296  106.515 106.551 1.00 40.91  ? 368 ASP A N   1 
ATOM   1598 C CA  . ASP A 1 368 ? 98.481  106.048 107.920 1.00 40.91  ? 368 ASP A CA  1 
ATOM   1599 C C   . ASP A 1 368 ? 98.130  107.154 108.907 1.00 40.91  ? 368 ASP A C   1 
ATOM   1600 O O   . ASP A 1 368 ? 98.560  108.301 108.755 1.00 40.91  ? 368 ASP A O   1 
ATOM   1601 C CB  . ASP A 1 368 ? 99.922  105.586 108.132 1.00 40.91  ? 368 ASP A CB  1 
ATOM   1602 C CG  . ASP A 1 368 ? 100.173 104.187 107.599 1.00 40.91  ? 368 ASP A CG  1 
ATOM   1603 O OD1 . ASP A 1 368 ? 99.193  103.457 107.345 1.00 40.91  ? 368 ASP A OD1 1 
ATOM   1604 O OD2 . ASP A 1 368 ? 101.355 103.818 107.433 1.00 40.91  ? 368 ASP A OD2 1 
ATOM   1605 N N   . THR A 1 369 ? 97.345  106.801 109.926 1.00 40.88  ? 369 THR A N   1 
ATOM   1606 C CA  . THR A 1 369 ? 96.895  107.794 110.894 1.00 40.88  ? 369 THR A CA  1 
ATOM   1607 C C   . THR A 1 369 ? 98.027  108.254 111.805 1.00 40.88  ? 369 THR A C   1 
ATOM   1608 O O   . THR A 1 369 ? 98.057  109.422 112.207 1.00 40.88  ? 369 THR A O   1 
ATOM   1609 C CB  . THR A 1 369 ? 95.751  107.224 111.731 1.00 40.88  ? 369 THR A CB  1 
ATOM   1610 O OG1 . THR A 1 369 ? 94.572  107.119 110.925 1.00 40.88  ? 369 THR A OG1 1 
ATOM   1611 C CG2 . THR A 1 369 ? 95.464  108.113 112.933 1.00 40.88  ? 369 THR A CG2 1 
ATOM   1612 N N   . GLU A 1 370 ? 98.958  107.365 112.137 1.00 32.29  ? 370 GLU A N   1 
ATOM   1613 C CA  . GLU A 1 370 ? 99.973  107.647 113.142 1.00 32.29  ? 370 GLU A CA  1 
ATOM   1614 C C   . GLU A 1 370 ? 101.156 108.443 112.607 1.00 32.29  ? 370 GLU A C   1 
ATOM   1615 O O   . GLU A 1 370 ? 102.191 108.497 113.279 1.00 32.29  ? 370 GLU A O   1 
ATOM   1616 C CB  . GLU A 1 370 ? 100.470 106.333 113.760 1.00 32.29  ? 370 GLU A CB  1 
ATOM   1617 C CG  . GLU A 1 370 ? 101.460 105.535 112.909 1.00 32.29  ? 370 GLU A CG  1 
ATOM   1618 C CD  . GLU A 1 370 ? 100.778 104.658 111.881 1.00 32.29  ? 370 GLU A CD  1 
ATOM   1619 O OE1 . GLU A 1 370 ? 99.535  104.712 111.778 1.00 32.29  ? 370 GLU A OE1 1 
ATOM   1620 O OE2 . GLU A 1 370 ? 101.487 103.914 111.173 1.00 32.29  ? 370 GLU A OE2 1 
ATOM   1621 N N   . ASN A 1 371 ? 101.048 109.053 111.426 1.00 31.72  ? 371 ASN A N   1 
ATOM   1622 C CA  . ASN A 1 371 ? 102.167 109.834 110.910 1.00 31.72  ? 371 ASN A CA  1 
ATOM   1623 C C   . ASN A 1 371 ? 102.435 111.051 111.786 1.00 31.72  ? 371 ASN A C   1 
ATOM   1624 O O   . ASN A 1 371 ? 103.596 111.379 112.072 1.00 31.72  ? 371 ASN A O   1 
ATOM   1625 C CB  . ASN A 1 371 ? 101.889 110.256 109.468 1.00 31.72  ? 371 ASN A CB  1 
ATOM   1626 C CG  . ASN A 1 371 ? 102.186 109.153 108.472 1.00 31.72  ? 371 ASN A CG  1 
ATOM   1627 O OD1 . ASN A 1 371 ? 103.199 108.464 108.575 1.00 31.72  ? 371 ASN A OD1 1 
ATOM   1628 N ND2 . ASN A 1 371 ? 101.297 108.978 107.502 1.00 31.72  ? 371 ASN A ND2 1 
ATOM   1629 N N   . ILE A 1 372 ? 101.376 111.729 112.228 1.00 31.70  ? 372 ILE A N   1 
ATOM   1630 C CA  . ILE A 1 372 ? 101.552 112.875 113.112 1.00 31.70  ? 372 ILE A CA  1 
ATOM   1631 C C   . ILE A 1 372 ? 102.234 112.442 114.401 1.00 31.70  ? 372 ILE A C   1 
ATOM   1632 O O   . ILE A 1 372 ? 103.148 113.112 114.894 1.00 31.70  ? 372 ILE A O   1 
ATOM   1633 C CB  . ILE A 1 372 ? 100.196 113.554 113.384 1.00 31.70  ? 372 ILE A CB  1 
ATOM   1634 C CG1 . ILE A 1 372 ? 99.259  112.611 114.144 1.00 31.70  ? 372 ILE A CG1 1 
ATOM   1635 C CG2 . ILE A 1 372 ? 99.555  113.991 112.079 1.00 31.70  ? 372 ILE A CG2 1 
ATOM   1636 C CD1 . ILE A 1 372 ? 97.846  113.131 114.288 1.00 31.70  ? 372 ILE A CD1 1 
ATOM   1637 N N   . ARG A 1 373 ? 101.807 111.311 114.964 1.00 27.87  ? 373 ARG A N   1 
ATOM   1638 C CA  . ARG A 1 373 ? 102.404 110.831 116.205 1.00 27.87  ? 373 ARG A CA  1 
ATOM   1639 C C   . ARG A 1 373 ? 103.868 110.458 116.006 1.00 27.87  ? 373 ARG A C   1 
ATOM   1640 O O   . ARG A 1 373 ? 104.707 110.744 116.868 1.00 27.87  ? 373 ARG A O   1 
ATOM   1641 C CB  . ARG A 1 373 ? 101.610 109.637 116.732 1.00 27.87  ? 373 ARG A CB  1 
ATOM   1642 C CG  . ARG A 1 373 ? 101.970 109.224 118.150 1.00 27.87  ? 373 ARG A CG  1 
ATOM   1643 C CD  . ARG A 1 373 ? 101.484 110.235 119.175 1.00 27.87  ? 373 ARG A CD  1 
ATOM   1644 N NE  . ARG A 1 373 ? 100.035 110.383 119.154 1.00 27.87  ? 373 ARG A NE  1 
ATOM   1645 C CZ  . ARG A 1 373 ? 99.345  111.127 120.009 1.00 27.87  ? 373 ARG A CZ  1 
ATOM   1646 N NH1 . ARG A 1 373 ? 99.944  111.805 120.974 1.00 27.87  ? 373 ARG A NH1 1 
ATOM   1647 N NH2 . ARG A 1 373 ? 98.023  111.189 119.893 1.00 27.87  ? 373 ARG A NH2 1 
ATOM   1648 N N   . ARG A 1 374 ? 104.192 109.816 114.884 1.00 24.95  ? 374 ARG A N   1 
ATOM   1649 C CA  . ARG A 1 374 ? 105.579 109.445 114.618 1.00 24.95  ? 374 ARG A CA  1 
ATOM   1650 C C   . ARG A 1 374 ? 106.461 110.681 114.514 1.00 24.95  ? 374 ARG A C   1 
ATOM   1651 O O   . ARG A 1 374 ? 107.547 110.739 115.106 1.00 24.95  ? 374 ARG A O   1 
ATOM   1652 C CB  . ARG A 1 374 ? 105.662 108.620 113.334 1.00 24.95  ? 374 ARG A CB  1 
ATOM   1653 C CG  . ARG A 1 374 ? 106.009 107.158 113.552 1.00 24.95  ? 374 ARG A CG  1 
ATOM   1654 C CD  . ARG A 1 374 ? 106.474 106.500 112.264 1.00 24.95  ? 374 ARG A CD  1 
ATOM   1655 N NE  . ARG A 1 374 ? 105.362 106.236 111.358 1.00 24.95  ? 374 ARG A NE  1 
ATOM   1656 C CZ  . ARG A 1 374 ? 104.607 105.147 111.391 1.00 24.95  ? 374 ARG A CZ  1 
ATOM   1657 N NH1 . ARG A 1 374 ? 104.813 104.187 112.278 1.00 24.95  ? 374 ARG A NH1 1 
ATOM   1658 N NH2 . ARG A 1 374 ? 103.617 105.019 110.514 1.00 24.95  ? 374 ARG A NH2 1 
ATOM   1659 N N   . VAL A 1 375 ? 106.007 111.687 113.763 1.00 22.62  ? 375 VAL A N   1 
ATOM   1660 C CA  . VAL A 1 375 ? 106.791 112.910 113.627 1.00 22.62  ? 375 VAL A CA  1 
ATOM   1661 C C   . VAL A 1 375 ? 106.929 113.603 114.976 1.00 22.62  ? 375 VAL A C   1 
ATOM   1662 O O   . VAL A 1 375 ? 107.999 114.118 115.320 1.00 22.62  ? 375 VAL A O   1 
ATOM   1663 C CB  . VAL A 1 375 ? 106.158 113.841 112.579 1.00 22.62  ? 375 VAL A CB  1 
ATOM   1664 C CG1 . VAL A 1 375 ? 106.881 115.176 112.553 1.00 22.62  ? 375 VAL A CG1 1 
ATOM   1665 C CG2 . VAL A 1 375 ? 106.186 113.189 111.209 1.00 22.62  ? 375 VAL A CG2 1 
ATOM   1666 N N   . PHE A 1 376 ? 105.848 113.634 115.760 1.00 23.99  ? 376 PHE A N   1 
ATOM   1667 C CA  . PHE A 1 376 ? 105.897 114.257 117.078 1.00 23.99  ? 376 PHE A CA  1 
ATOM   1668 C C   . PHE A 1 376 ? 106.939 113.584 117.964 1.00 23.99  ? 376 PHE A C   1 
ATOM   1669 O O   . PHE A 1 376 ? 107.770 114.252 118.590 1.00 23.99  ? 376 PHE A O   1 
ATOM   1670 C CB  . PHE A 1 376 ? 104.510 114.191 117.719 1.00 23.99  ? 376 PHE A CB  1 
ATOM   1671 C CG  . PHE A 1 376 ? 104.505 114.464 119.193 1.00 23.99  ? 376 PHE A CG  1 
ATOM   1672 C CD1 . PHE A 1 376 ? 104.696 115.744 119.678 1.00 23.99  ? 376 PHE A CD1 1 
ATOM   1673 C CD2 . PHE A 1 376 ? 104.297 113.440 120.097 1.00 23.99  ? 376 PHE A CD2 1 
ATOM   1674 C CE1 . PHE A 1 376 ? 104.690 115.995 121.033 1.00 23.99  ? 376 PHE A CE1 1 
ATOM   1675 C CE2 . PHE A 1 376 ? 104.288 113.687 121.453 1.00 23.99  ? 376 PHE A CE2 1 
ATOM   1676 C CZ  . PHE A 1 376 ? 104.484 114.966 121.921 1.00 23.99  ? 376 PHE A CZ  1 
ATOM   1677 N N   . ASN A 1 377 ? 106.914 112.253 118.019 1.00 22.01  ? 377 ASN A N   1 
ATOM   1678 C CA  . ASN A 1 377 ? 107.852 111.537 118.873 1.00 22.01  ? 377 ASN A CA  1 
ATOM   1679 C C   . ASN A 1 377 ? 109.286 111.725 118.398 1.00 22.01  ? 377 ASN A C   1 
ATOM   1680 O O   . ASN A 1 377 ? 110.201 111.883 119.215 1.00 22.01  ? 377 ASN A O   1 
ATOM   1681 C CB  . ASN A 1 377 ? 107.484 110.056 118.918 1.00 22.01  ? 377 ASN A CB  1 
ATOM   1682 C CG  . ASN A 1 377 ? 106.086 109.824 119.454 1.00 22.01  ? 377 ASN A CG  1 
ATOM   1683 O OD1 . ASN A 1 377 ? 105.554 110.643 120.201 1.00 22.01  ? 377 ASN A OD1 1 
ATOM   1684 N ND2 . ASN A 1 377 ? 105.483 108.705 119.076 1.00 22.01  ? 377 ASN A ND2 1 
ATOM   1685 N N   . ASP A 1 378 ? 109.510 111.712 117.082 1.00 19.85  ? 378 ASP A N   1 
ATOM   1686 C CA  . ASP A 1 378 ? 110.869 111.901 116.583 1.00 19.85  ? 378 ASP A CA  1 
ATOM   1687 C C   . ASP A 1 378 ? 111.374 113.309 116.882 1.00 19.85  ? 378 ASP A C   1 
ATOM   1688 O O   . ASP A 1 378 ? 112.548 113.495 117.223 1.00 19.85  ? 378 ASP A O   1 
ATOM   1689 C CB  . ASP A 1 378 ? 110.923 111.606 115.084 1.00 19.85  ? 378 ASP A CB  1 
ATOM   1690 C CG  . ASP A 1 378 ? 111.187 110.136 114.788 1.00 19.85  ? 378 ASP A CG  1 
ATOM   1691 O OD1 . ASP A 1 378 ? 111.576 109.395 115.714 1.00 19.85  ? 378 ASP A OD1 1 
ATOM   1692 O OD2 . ASP A 1 378 ? 111.004 109.718 113.626 1.00 19.85  ? 378 ASP A OD2 1 
ATOM   1693 N N   . CYS A 1 379 ? 110.502 114.313 116.773 1.00 19.98  ? 379 CYS A N   1 
ATOM   1694 C CA  . CYS A 1 379 ? 110.893 115.664 117.157 1.00 19.98  ? 379 CYS A CA  1 
ATOM   1695 C C   . CYS A 1 379 ? 111.250 115.727 118.636 1.00 19.98  ? 379 CYS A C   1 
ATOM   1696 O O   . CYS A 1 379 ? 112.244 116.357 119.018 1.00 19.98  ? 379 CYS A O   1 
ATOM   1697 C CB  . CYS A 1 379 ? 109.764 116.643 116.839 1.00 19.98  ? 379 CYS A CB  1 
ATOM   1698 S SG  . CYS A 1 379 ? 109.569 117.010 115.084 1.00 19.98  ? 379 CYS A SG  1 
ATOM   1699 N N   . ARG A 1 380 ? 110.446 115.083 119.484 1.00 22.71  ? 380 ARG A N   1 
ATOM   1700 C CA  . ARG A 1 380 ? 110.753 115.064 120.910 1.00 22.71  ? 380 ARG A CA  1 
ATOM   1701 C C   . ARG A 1 380 ? 112.119 114.444 121.162 1.00 22.71  ? 380 ARG A C   1 
ATOM   1702 O O   . ARG A 1 380 ? 112.915 114.966 121.953 1.00 22.71  ? 380 ARG A O   1 
ATOM   1703 C CB  . ARG A 1 380 ? 109.672 114.298 121.667 1.00 22.71  ? 380 ARG A CB  1 
ATOM   1704 C CG  . ARG A 1 380 ? 110.011 114.019 123.118 1.00 22.71  ? 380 ARG A CG  1 
ATOM   1705 C CD  . ARG A 1 380 ? 108.842 113.385 123.842 1.00 22.71  ? 380 ARG A CD  1 
ATOM   1706 N NE  . ARG A 1 380 ? 108.890 111.930 123.760 1.00 22.71  ? 380 ARG A NE  1 
ATOM   1707 C CZ  . ARG A 1 380 ? 107.828 111.138 123.701 1.00 22.71  ? 380 ARG A CZ  1 
ATOM   1708 N NH1 . ARG A 1 380 ? 106.597 111.624 123.727 1.00 22.71  ? 380 ARG A NH1 1 
ATOM   1709 N NH2 . ARG A 1 380 ? 108.004 109.823 123.613 1.00 22.71  ? 380 ARG A NH2 1 
ATOM   1710 N N   . ASP A 1 381 ? 112.408 113.327 120.495 1.00 20.14  ? 381 ASP A N   1 
ATOM   1711 C CA  . ASP A 1 381 ? 113.712 112.695 120.650 1.00 20.14  ? 381 ASP A CA  1 
ATOM   1712 C C   . ASP A 1 381 ? 114.832 113.625 120.205 1.00 20.14  ? 381 ASP A C   1 
ATOM   1713 O O   . ASP A 1 381 ? 115.887 113.685 120.844 1.00 20.14  ? 381 ASP A O   1 
ATOM   1714 C CB  . ASP A 1 381 ? 113.763 111.391 119.859 1.00 20.14  ? 381 ASP A CB  1 
ATOM   1715 C CG  . ASP A 1 381 ? 115.141 110.767 119.858 1.00 20.14  ? 381 ASP A CG  1 
ATOM   1716 O OD1 . ASP A 1 381 ? 115.543 110.203 120.895 1.00 20.14  ? 381 ASP A OD1 1 
ATOM   1717 O OD2 . ASP A 1 381 ? 115.827 110.843 118.819 1.00 20.14  ? 381 ASP A OD2 1 
ATOM   1718 N N   . ILE A 1 382 ? 114.629 114.350 119.104 1.00 19.73  ? 382 ILE A N   1 
ATOM   1719 C CA  . ILE A 1 382 ? 115.663 115.261 118.617 1.00 19.73  ? 382 ILE A CA  1 
ATOM   1720 C C   . ILE A 1 382 ? 115.953 116.336 119.656 1.00 19.73  ? 382 ILE A C   1 
ATOM   1721 O O   . ILE A 1 382 ? 117.114 116.629 119.970 1.00 19.73  ? 382 ILE A O   1 
ATOM   1722 C CB  . ILE A 1 382 ? 115.242 115.881 117.273 1.00 19.73  ? 382 ILE A CB  1 
ATOM   1723 C CG1 . ILE A 1 382 ? 115.322 114.842 116.149 1.00 19.73  ? 382 ILE A CG1 1 
ATOM   1724 C CG2 . ILE A 1 382 ? 116.100 117.094 116.952 1.00 19.73  ? 382 ILE A CG2 1 
ATOM   1725 C CD1 . ILE A 1 382 ? 116.718 114.302 115.893 1.00 19.73  ? 382 ILE A CD1 1 
ATOM   1726 N N   . ILE A 1 383 ? 114.898 116.945 120.203 1.00 21.50  ? 383 ILE A N   1 
ATOM   1727 C CA  . ILE A 1 383 ? 115.103 118.002 121.193 1.00 21.50  ? 383 ILE A CA  1 
ATOM   1728 C C   . ILE A 1 383 ? 115.805 117.450 122.426 1.00 21.50  ? 383 ILE A C   1 
ATOM   1729 O O   . ILE A 1 383 ? 116.722 118.080 122.968 1.00 21.50  ? 383 ILE A O   1 
ATOM   1730 C CB  . ILE A 1 383 ? 113.771 118.684 121.564 1.00 21.50  ? 383 ILE A CB  1 
ATOM   1731 C CG1 . ILE A 1 383 ? 112.975 119.074 120.317 1.00 21.50  ? 383 ILE A CG1 1 
ATOM   1732 C CG2 . ILE A 1 383 ? 114.030 119.905 122.423 1.00 21.50  ? 383 ILE A CG2 1 
ATOM   1733 C CD1 . ILE A 1 383 ? 113.678 120.076 119.425 1.00 21.50  ? 383 ILE A CD1 1 
ATOM   1734 N N   . GLN A 1 384 ? 115.383 116.276 122.899 1.00 20.82  ? 384 GLN A N   1 
ATOM   1735 C CA  . GLN A 1 384 ? 116.015 115.705 124.083 1.00 20.82  ? 384 GLN A CA  1 
ATOM   1736 C C   . GLN A 1 384 ? 117.489 115.409 123.834 1.00 20.82  ? 384 GLN A C   1 
ATOM   1737 O O   . GLN A 1 384 ? 118.336 115.673 124.696 1.00 20.82  ? 384 GLN A O   1 
ATOM   1738 C CB  . GLN A 1 384 ? 115.280 114.442 124.514 1.00 20.82  ? 384 GLN A CB  1 
ATOM   1739 C CG  . GLN A 1 384 ? 113.944 114.715 125.162 1.00 20.82  ? 384 GLN A CG  1 
ATOM   1740 C CD  . GLN A 1 384 ? 113.374 113.494 125.836 1.00 20.82  ? 384 GLN A CD  1 
ATOM   1741 O OE1 . GLN A 1 384 ? 113.975 112.423 125.811 1.00 20.82  ? 384 GLN A OE1 1 
ATOM   1742 N NE2 . GLN A 1 384 ? 112.205 113.644 126.443 1.00 20.82  ? 384 GLN A NE2 1 
ATOM   1743 N N   . ARG A 1 385 ? 117.817 114.855 122.666 1.00 26.12  ? 385 ARG A N   1 
ATOM   1744 C CA  . ARG A 1 385 ? 119.214 114.573 122.356 1.00 26.12  ? 385 ARG A CA  1 
ATOM   1745 C C   . ARG A 1 385 ? 120.034 115.853 122.324 1.00 26.12  ? 385 ARG A C   1 
ATOM   1746 O O   . ARG A 1 385 ? 121.153 115.898 122.846 1.00 26.12  ? 385 ARG A O   1 
ATOM   1747 C CB  . ARG A 1 385 ? 119.323 113.836 121.022 1.00 26.12  ? 385 ARG A CB  1 
ATOM   1748 C CG  . ARG A 1 385 ? 119.500 112.338 121.160 1.00 26.12  ? 385 ARG A CG  1 
ATOM   1749 C CD  . ARG A 1 385 ? 119.704 111.676 119.812 1.00 26.12  ? 385 ARG A CD  1 
ATOM   1750 N NE  . ARG A 1 385 ? 119.072 110.364 119.754 1.00 26.12  ? 385 ARG A NE  1 
ATOM   1751 C CZ  . ARG A 1 385 ? 119.652 109.233 120.128 1.00 26.12  ? 385 ARG A CZ  1 
ATOM   1752 N NH1 . ARG A 1 385 ? 120.891 109.208 120.589 1.00 26.12  ? 385 ARG A NH1 1 
ATOM   1753 N NH2 . ARG A 1 385 ? 118.970 108.095 120.038 1.00 26.12  ? 385 ARG A NH2 1 
ATOM   1754 N N   . MET A 1 386 ? 119.498 116.909 121.709 1.00 24.47  ? 386 MET A N   1 
ATOM   1755 C CA  . MET A 1 386 ? 120.234 118.170 121.661 1.00 24.47  ? 386 MET A CA  1 
ATOM   1756 C C   . MET A 1 386 ? 120.461 118.719 123.063 1.00 24.47  ? 386 MET A C   1 
ATOM   1757 O O   . MET A 1 386 ? 121.566 119.159 123.403 1.00 24.47  ? 386 MET A O   1 
ATOM   1758 C CB  . MET A 1 386 ? 119.482 119.184 120.800 1.00 24.47  ? 386 MET A CB  1 
ATOM   1759 C CG  . MET A 1 386 ? 120.194 120.522 120.668 1.00 24.47  ? 386 MET A CG  1 
ATOM   1760 S SD  . MET A 1 386 ? 119.481 121.862 121.648 1.00 24.47  ? 386 MET A SD  1 
ATOM   1761 C CE  . MET A 1 386 ? 117.756 121.812 121.161 1.00 24.47  ? 386 MET A CE  1 
ATOM   1762 N N   . HIS A 1 387 ? 119.421 118.689 123.899 1.00 23.31  ? 387 HIS A N   1 
ATOM   1763 C CA  . HIS A 1 387 ? 119.559 119.174 125.267 1.00 23.31  ? 387 HIS A CA  1 
ATOM   1764 C C   . HIS A 1 387 ? 120.633 118.397 126.014 1.00 23.31  ? 387 HIS A C   1 
ATOM   1765 O O   . HIS A 1 387 ? 121.504 118.985 126.662 1.00 23.31  ? 387 HIS A O   1 
ATOM   1766 C CB  . HIS A 1 387 ? 118.220 119.068 125.997 1.00 23.31  ? 387 HIS A CB  1 
ATOM   1767 C CG  . HIS A 1 387 ? 117.269 120.180 125.686 1.00 23.31  ? 387 HIS A CG  1 
ATOM   1768 N ND1 . HIS A 1 387 ? 117.688 121.444 125.338 1.00 23.31  ? 387 HIS A ND1 1 
ATOM   1769 C CD2 . HIS A 1 387 ? 115.916 120.215 125.672 1.00 23.31  ? 387 HIS A CD2 1 
ATOM   1770 C CE1 . HIS A 1 387 ? 116.635 122.212 125.123 1.00 23.31  ? 387 HIS A CE1 1 
ATOM   1771 N NE2 . HIS A 1 387 ? 115.547 121.490 125.318 1.00 23.31  ? 387 HIS A NE2 1 
ATOM   1772 N N   . LEU A 1 388 ? 120.588 117.067 125.931 1.00 24.93  ? 388 LEU A N   1 
ATOM   1773 C CA  . LEU A 1 388 ? 121.585 116.262 126.626 1.00 24.93  ? 388 LEU A CA  1 
ATOM   1774 C C   . LEU A 1 388 ? 122.983 116.537 126.098 1.00 24.93  ? 388 LEU A C   1 
ATOM   1775 O O   . LEU A 1 388 ? 123.946 116.541 126.871 1.00 24.93  ? 388 LEU A O   1 
ATOM   1776 C CB  . LEU A 1 388 ? 121.249 114.779 126.494 1.00 24.93  ? 388 LEU A CB  1 
ATOM   1777 C CG  . LEU A 1 388 ? 119.981 114.332 127.224 1.00 24.93  ? 388 LEU A CG  1 
ATOM   1778 C CD1 . LEU A 1 388 ? 119.538 112.960 126.756 1.00 24.93  ? 388 LEU A CD1 1 
ATOM   1779 C CD2 . LEU A 1 388 ? 120.201 114.335 128.722 1.00 24.93  ? 388 LEU A CD2 1 
ATOM   1780 N N   . ARG A 1 389 ? 123.121 116.771 124.793 1.00 28.80  ? 389 ARG A N   1 
ATOM   1781 C CA  . ARG A 1 389 ? 124.436 117.080 124.240 1.00 28.80  ? 389 ARG A CA  1 
ATOM   1782 C C   . ARG A 1 389 ? 124.937 118.429 124.734 1.00 28.80  ? 389 ARG A C   1 
ATOM   1783 O O   . ARG A 1 389 ? 126.150 118.644 124.843 1.00 28.80  ? 389 ARG A O   1 
ATOM   1784 C CB  . ARG A 1 389 ? 124.384 117.054 122.714 1.00 28.80  ? 389 ARG A CB  1 
ATOM   1785 C CG  . ARG A 1 389 ? 124.208 115.664 122.121 1.00 28.80  ? 389 ARG A CG  1 
ATOM   1786 C CD  . ARG A 1 389 ? 125.411 114.773 122.387 1.00 28.80  ? 389 ARG A CD  1 
ATOM   1787 N NE  . ARG A 1 389 ? 126.664 115.394 121.975 1.00 28.80  ? 389 ARG A NE  1 
ATOM   1788 C CZ  . ARG A 1 389 ? 127.082 115.480 120.720 1.00 28.80  ? 389 ARG A CZ  1 
ATOM   1789 N NH1 . ARG A 1 389 ? 126.365 114.999 119.717 1.00 28.80  ? 389 ARG A NH1 1 
ATOM   1790 N NH2 . ARG A 1 389 ? 128.250 116.062 120.463 1.00 28.80  ? 389 ARG A NH2 1 
ATOM   1791 N N   . GLN A 1 390 ? 124.024 119.357 125.030 1.00 25.46  ? 390 GLN A N   1 
ATOM   1792 C CA  . GLN A 1 390 ? 124.450 120.644 125.573 1.00 25.46  ? 390 GLN A CA  1 
ATOM   1793 C C   . GLN A 1 390 ? 125.134 120.472 126.923 1.00 25.46  ? 390 GLN A C   1 
ATOM   1794 O O   . GLN A 1 390 ? 126.167 121.097 127.186 1.00 25.46  ? 390 GLN A O   1 
ATOM   1795 C CB  . GLN A 1 390 ? 123.255 121.586 125.695 1.00 25.46  ? 390 GLN A CB  1 
ATOM   1796 C CG  . GLN A 1 390 ? 123.016 122.429 124.457 1.00 25.46  ? 390 GLN A CG  1 
ATOM   1797 C CD  . GLN A 1 390 ? 121.769 123.280 124.565 1.00 25.46  ? 390 GLN A CD  1 
ATOM   1798 O OE1 . GLN A 1 390 ? 121.084 123.273 125.588 1.00 25.46  ? 390 GLN A OE1 1 
ATOM   1799 N NE2 . GLN A 1 390 ? 121.465 124.019 123.505 1.00 25.46  ? 390 GLN A NE2 1 
ATOM   1800 N N   . TYR A 1 391 ? 124.578 119.627 127.789 1.00 21.84  ? 391 TYR A N   1 
ATOM   1801 C CA  . TYR A 1 391 ? 125.171 119.343 129.091 1.00 21.84  ? 391 TYR A CA  1 
ATOM   1802 C C   . TYR A 1 391 ? 126.350 118.385 129.011 1.00 21.84  ? 391 TYR A C   1 
ATOM   1803 O O   . TYR A 1 391 ? 126.902 118.019 130.054 1.00 21.84  ? 391 TYR A O   1 
ATOM   1804 C CB  . TYR A 1 391 ? 124.117 118.761 130.034 1.00 21.84  ? 391 TYR A CB  1 
ATOM   1805 C CG  . TYR A 1 391 ? 123.311 119.798 130.777 1.00 21.84  ? 391 TYR A CG  1 
ATOM   1806 C CD1 . TYR A 1 391 ? 123.825 120.426 131.901 1.00 21.84  ? 391 TYR A CD1 1 
ATOM   1807 C CD2 . TYR A 1 391 ? 122.039 120.149 130.357 1.00 21.84  ? 391 TYR A CD2 1 
ATOM   1808 C CE1 . TYR A 1 391 ? 123.092 121.373 132.586 1.00 21.84  ? 391 TYR A CE1 1 
ATOM   1809 C CE2 . TYR A 1 391 ? 121.300 121.095 131.034 1.00 21.84  ? 391 TYR A CE2 1 
ATOM   1810 C CZ  . TYR A 1 391 ? 121.830 121.702 132.149 1.00 21.84  ? 391 TYR A CZ  1 
ATOM   1811 O OH  . TYR A 1 391 ? 121.095 122.646 132.826 1.00 21.84  ? 391 TYR A OH  1 
ATOM   1812 N N   . GLU A 1 392 ? 126.741 117.963 127.810 1.00 30.52  ? 392 GLU A N   1 
ATOM   1813 C CA  . GLU A 1 392 ? 127.862 117.047 127.626 1.00 30.52  ? 392 GLU A CA  1 
ATOM   1814 C C   . GLU A 1 392 ? 127.635 115.725 128.346 1.00 30.52  ? 392 GLU A C   1 
ATOM   1815 O O   . GLU A 1 392 ? 128.589 115.037 128.716 1.00 30.52  ? 392 GLU A O   1 
ATOM   1816 C CB  . GLU A 1 392 ? 129.175 117.684 128.084 1.00 30.52  ? 392 GLU A CB  1 
ATOM   1817 C CG  . GLU A 1 392 ? 129.569 118.902 127.275 1.00 30.52  ? 392 GLU A CG  1 
ATOM   1818 C CD  . GLU A 1 392 ? 130.831 119.557 127.792 1.00 30.52  ? 392 GLU A CD  1 
ATOM   1819 O OE1 . GLU A 1 392 ? 130.909 119.830 129.008 1.00 30.52  ? 392 GLU A OE1 1 
ATOM   1820 O OE2 . GLU A 1 392 ? 131.747 119.806 126.979 1.00 30.52  ? 392 GLU A OE2 1 
ATOM   1821 N N   . LEU A 1 393 ? 126.371 115.356 128.558 1.00 27.72  ? 393 LEU A N   1 
ATOM   1822 C CA  . LEU A 1 393 ? 126.077 114.022 129.072 1.00 27.72  ? 393 LEU A CA  1 
ATOM   1823 C C   . LEU A 1 393 ? 126.315 112.966 128.003 1.00 27.72  ? 393 LEU A C   1 
ATOM   1824 O O   . LEU A 1 393 ? 126.905 111.915 128.281 1.00 27.72  ? 393 LEU A O   1 
ATOM   1825 C CB  . LEU A 1 393 ? 124.637 113.952 129.577 1.00 27.72  ? 393 LEU A CB  1 
ATOM   1826 C CG  . LEU A 1 393 ? 124.339 114.684 130.887 1.00 27.72  ? 393 LEU A CG  1 
ATOM   1827 C CD1 . LEU A 1 393 ? 122.844 114.693 131.159 1.00 27.72  ? 393 LEU A CD1 1 
ATOM   1828 C CD2 . LEU A 1 393 ? 125.089 114.051 132.045 1.00 27.72  ? 393 LEU A CD2 1 
ATOM   1829 N N   . LEU A 1 394 ? 125.871 113.228 126.779 1.00 29.65  ? 394 LEU A N   1 
ATOM   1830 C CA  . LEU A 1 394 ? 126.060 112.300 125.670 1.00 29.65  ? 394 LEU A CA  1 
ATOM   1831 C C   . LEU A 1 394 ? 127.177 112.782 124.755 1.00 29.65  ? 394 LEU A C   1 
ATOM   1832 O O   . LEU A 1 394 ? 127.418 113.984 124.635 0.00 29.65  ? 394 LEU A O   1 
ATOM   1833 C CB  . LEU A 1 394 ? 124.761 112.144 124.876 1.00 29.65  ? 394 LEU A CB  1 
ATOM   1834 C CG  . LEU A 1 394 ? 123.805 111.057 125.370 1.00 29.65  ? 394 LEU A CG  1 
ATOM   1835 C CD1 . LEU A 1 394 ? 123.410 111.304 126.816 1.00 29.65  ? 394 LEU A CD1 1 
ATOM   1836 C CD2 . LEU A 1 394 ? 122.575 110.992 124.483 1.00 29.65  ? 394 LEU A CD2 1 
ATOM   1837 N N   . LEU B 2 4   ? 120.650 120.831 62.726  1.00 86.32  ? 4   LEU B N   1 
ATOM   1838 C CA  . LEU B 2 4   ? 121.119 121.377 63.993  1.00 86.32  ? 4   LEU B CA  1 
ATOM   1839 C C   . LEU B 2 4   ? 122.638 121.435 64.082  1.00 86.32  ? 4   LEU B C   1 
ATOM   1840 O O   . LEU B 2 4   ? 123.175 122.283 64.804  1.00 86.32  ? 4   LEU B O   1 
ATOM   1841 C CB  . LEU B 2 4   ? 120.565 120.545 65.153  1.00 86.32  ? 4   LEU B CB  1 
ATOM   1842 C CG  . LEU B 2 4   ? 120.805 121.082 66.565  1.00 86.32  ? 4   LEU B CG  1 
ATOM   1843 C CD1 . LEU B 2 4   ? 119.603 120.797 67.449  1.00 86.32  ? 4   LEU B CD1 1 
ATOM   1844 C CD2 . LEU B 2 4   ? 122.061 120.475 67.174  1.00 86.32  ? 4   LEU B CD2 1 
ATOM   1845 N N   . ASP B 2 5   ? 123.342 120.561 63.360  1.00 95.89  ? 5   ASP B N   1 
ATOM   1846 C CA  . ASP B 2 5   ? 124.800 120.551 63.428  1.00 95.89  ? 5   ASP B CA  1 
ATOM   1847 C C   . ASP B 2 5   ? 125.387 121.861 62.915  1.00 95.89  ? 5   ASP B C   1 
ATOM   1848 O O   . ASP B 2 5   ? 126.371 122.369 63.468  1.00 95.89  ? 5   ASP B O   1 
ATOM   1849 C CB  . ASP B 2 5   ? 125.350 119.371 62.629  1.00 95.89  ? 5   ASP B CB  1 
ATOM   1850 N N   . GLN B 2 6   ? 124.803 122.419 61.853  1.00 88.75  ? 6   GLN B N   1 
ATOM   1851 C CA  . GLN B 2 6   ? 125.325 123.660 61.291  1.00 88.75  ? 6   GLN B CA  1 
ATOM   1852 C C   . GLN B 2 6   ? 125.263 124.793 62.308  1.00 88.75  ? 6   GLN B C   1 
ATOM   1853 O O   . GLN B 2 6   ? 126.183 125.615 62.389  1.00 88.75  ? 6   GLN B O   1 
ATOM   1854 C CB  . GLN B 2 6   ? 124.552 124.028 60.025  1.00 88.75  ? 6   GLN B CB  1 
ATOM   1855 N N   . LEU B 2 7   ? 124.182 124.858 63.088  1.00 83.99  ? 7   LEU B N   1 
ATOM   1856 C CA  . LEU B 2 7   ? 124.078 125.894 64.110  1.00 83.99  ? 7   LEU B CA  1 
ATOM   1857 C C   . LEU B 2 7   ? 125.157 125.728 65.171  1.00 83.99  ? 7   LEU B C   1 
ATOM   1858 O O   . LEU B 2 7   ? 125.751 126.712 65.625  1.00 83.99  ? 7   LEU B O   1 
ATOM   1859 C CB  . LEU B 2 7   ? 122.688 125.865 64.742  1.00 83.99  ? 7   LEU B CB  1 
ATOM   1860 C CG  . LEU B 2 7   ? 121.519 126.000 63.763  1.00 83.99  ? 7   LEU B CG  1 
ATOM   1861 C CD1 . LEU B 2 7   ? 120.197 126.020 64.509  1.00 83.99  ? 7   LEU B CD1 1 
ATOM   1862 C CD2 . LEU B 2 7   ? 121.667 127.246 62.900  1.00 83.99  ? 7   LEU B CD2 1 
ATOM   1863 N N   . ARG B 2 8   ? 125.425 124.486 65.581  1.00 80.14  ? 8   ARG B N   1 
ATOM   1864 C CA  . ARG B 2 8   ? 126.494 124.243 66.544  1.00 80.14  ? 8   ARG B CA  1 
ATOM   1865 C C   . ARG B 2 8   ? 127.839 124.685 65.984  1.00 80.14  ? 8   ARG B C   1 
ATOM   1866 O O   . ARG B 2 8   ? 128.646 125.305 66.685  1.00 80.14  ? 8   ARG B O   1 
ATOM   1867 C CB  . ARG B 2 8   ? 126.533 122.764 66.923  1.00 80.14  ? 8   ARG B CB  1 
ATOM   1868 C CG  . ARG B 2 8   ? 125.396 122.320 67.826  1.00 80.14  ? 8   ARG B CG  1 
ATOM   1869 C CD  . ARG B 2 8   ? 125.577 120.874 68.260  1.00 80.14  ? 8   ARG B CD  1 
ATOM   1870 N NE  . ARG B 2 8   ? 124.661 120.499 69.330  1.00 80.14  ? 8   ARG B NE  1 
ATOM   1871 C CZ  . ARG B 2 8   ? 124.670 119.326 69.948  1.00 80.14  ? 8   ARG B CZ  1 
ATOM   1872 N NH1 . ARG B 2 8   ? 125.543 118.384 69.630  1.00 80.14  ? 8   ARG B NH1 1 
ATOM   1873 N NH2 . ARG B 2 8   ? 123.781 119.091 70.909  1.00 80.14  ? 8   ARG B NH2 1 
ATOM   1874 N N   . GLN B 2 9   ? 128.099 124.370 64.713  1.00 80.39  ? 9   GLN B N   1 
ATOM   1875 C CA  . GLN B 2 9   ? 129.360 124.775 64.100  1.00 80.39  ? 9   GLN B CA  1 
ATOM   1876 C C   . GLN B 2 9   ? 129.480 126.293 64.043  1.00 80.39  ? 9   GLN B C   1 
ATOM   1877 O O   . GLN B 2 9   ? 130.550 126.852 64.320  1.00 80.39  ? 9   GLN B O   1 
ATOM   1878 C CB  . GLN B 2 9   ? 129.476 124.175 62.699  1.00 80.39  ? 9   GLN B CB  1 
ATOM   1879 C CG  . GLN B 2 9   ? 130.901 124.070 62.187  1.00 80.39  ? 9   GLN B CG  1 
ATOM   1880 C CD  . GLN B 2 9   ? 131.724 123.057 62.958  1.00 80.39  ? 9   GLN B CD  1 
ATOM   1881 O OE1 . GLN B 2 9   ? 131.204 122.345 63.818  1.00 80.39  ? 9   GLN B OE1 1 
ATOM   1882 N NE2 . GLN B 2 9   ? 133.014 122.986 62.653  1.00 80.39  ? 9   GLN B NE2 1 
ATOM   1883 N N   . GLU B 2 10  ? 128.393 126.978 63.680  1.00 80.48  ? 10  GLU B N   1 
ATOM   1884 C CA  . GLU B 2 10  ? 128.423 128.435 63.627  1.00 80.48  ? 10  GLU B CA  1 
ATOM   1885 C C   . GLU B 2 10  ? 128.678 129.029 65.005  1.00 80.48  ? 10  GLU B C   1 
ATOM   1886 O O   . GLU B 2 10  ? 129.456 129.981 65.147  1.00 80.48  ? 10  GLU B O   1 
ATOM   1887 C CB  . GLU B 2 10  ? 127.111 128.964 63.050  1.00 80.48  ? 10  GLU B CB  1 
ATOM   1888 N N   . ALA B 2 11  ? 128.027 128.484 66.035  1.00 75.43  ? 11  ALA B N   1 
ATOM   1889 C CA  . ALA B 2 11  ? 128.257 128.974 67.390  1.00 75.43  ? 11  ALA B CA  1 
ATOM   1890 C C   . ALA B 2 11  ? 129.703 128.754 67.813  1.00 75.43  ? 11  ALA B C   1 
ATOM   1891 O O   . ALA B 2 11  ? 130.316 129.628 68.437  1.00 75.43  ? 11  ALA B O   1 
ATOM   1892 C CB  . ALA B 2 11  ? 127.301 128.290 68.365  1.00 75.43  ? 11  ALA B CB  1 
ATOM   1893 N N   . GLU B 2 12  ? 130.264 127.589 67.483  1.00 75.74  ? 12  GLU B N   1 
ATOM   1894 C CA  . GLU B 2 12  ? 131.656 127.321 67.828  1.00 75.74  ? 12  GLU B CA  1 
ATOM   1895 C C   . GLU B 2 12  ? 132.591 128.300 67.130  1.00 75.74  ? 12  GLU B C   1 
ATOM   1896 O O   . GLU B 2 12  ? 133.537 128.813 67.741  1.00 75.74  ? 12  GLU B O   1 
ATOM   1897 C CB  . GLU B 2 12  ? 132.015 125.881 67.461  1.00 75.74  ? 12  GLU B CB  1 
ATOM   1898 C CG  . GLU B 2 12  ? 133.393 125.439 67.933  1.00 75.74  ? 12  GLU B CG  1 
ATOM   1899 C CD  . GLU B 2 12  ? 134.503 125.837 66.977  1.00 75.74  ? 12  GLU B CD  1 
ATOM   1900 O OE1 . GLU B 2 12  ? 134.214 126.065 65.783  1.00 75.74  ? 12  GLU B OE1 1 
ATOM   1901 O OE2 . GLU B 2 12  ? 135.667 125.922 67.421  1.00 75.74  ? 12  GLU B OE2 1 
ATOM   1902 N N   . GLN B 2 13  ? 132.345 128.571 65.847  1.00 79.10  ? 13  GLN B N   1 
ATOM   1903 C CA  . GLN B 2 13  ? 133.196 129.508 65.120  1.00 79.10  ? 13  GLN B CA  1 
ATOM   1904 C C   . GLN B 2 13  ? 133.087 130.914 65.697  1.00 79.10  ? 13  GLN B C   1 
ATOM   1905 O O   . GLN B 2 13  ? 134.091 131.624 65.818  1.00 79.10  ? 13  GLN B O   1 
ATOM   1906 C CB  . GLN B 2 13  ? 132.829 129.506 63.635  1.00 79.10  ? 13  GLN B CB  1 
ATOM   1907 C CG  . GLN B 2 13  ? 133.230 128.239 62.892  1.00 79.10  ? 13  GLN B CG  1 
ATOM   1908 C CD  . GLN B 2 13  ? 134.687 127.873 63.094  1.00 79.10  ? 13  GLN B CD  1 
ATOM   1909 O OE1 . GLN B 2 13  ? 135.549 128.746 63.186  1.00 79.10  ? 13  GLN B OE1 1 
ATOM   1910 N NE2 . GLN B 2 13  ? 134.968 126.578 63.171  1.00 79.10  ? 13  GLN B NE2 1 
ATOM   1911 N N   . LEU B 2 14  ? 131.872 131.337 66.055  1.00 74.55  ? 14  LEU B N   1 
ATOM   1912 C CA  . LEU B 2 14  ? 131.708 132.654 66.664  1.00 74.55  ? 14  LEU B CA  1 
ATOM   1913 C C   . LEU B 2 14  ? 132.438 132.736 67.998  1.00 74.55  ? 14  LEU B C   1 
ATOM   1914 O O   . LEU B 2 14  ? 133.079 133.748 68.304  1.00 74.55  ? 14  LEU B O   1 
ATOM   1915 C CB  . LEU B 2 14  ? 130.224 132.966 66.844  1.00 74.55  ? 14  LEU B CB  1 
ATOM   1916 C CG  . LEU B 2 14  ? 129.457 133.216 65.546  1.00 74.55  ? 14  LEU B CG  1 
ATOM   1917 C CD1 . LEU B 2 14  ? 127.975 132.955 65.745  1.00 74.55  ? 14  LEU B CD1 1 
ATOM   1918 C CD2 . LEU B 2 14  ? 129.694 134.633 65.051  1.00 74.55  ? 14  LEU B CD2 1 
ATOM   1919 N N   . LYS B 2 15  ? 132.351 131.679 68.810  1.00 74.42  ? 15  LYS B N   1 
ATOM   1920 C CA  . LYS B 2 15  ? 133.068 131.671 70.080  1.00 74.42  ? 15  LYS B CA  1 
ATOM   1921 C C   . LYS B 2 15  ? 134.573 131.748 69.855  1.00 74.42  ? 15  LYS B C   1 
ATOM   1922 O O   . LYS B 2 15  ? 135.281 132.464 70.573  1.00 74.42  ? 15  LYS B O   1 
ATOM   1923 C CB  . LYS B 2 15  ? 132.708 130.418 70.876  1.00 74.42  ? 15  LYS B CB  1 
ATOM   1924 N N   . ASN B 2 16  ? 135.080 131.016 68.861  1.00 75.96  ? 16  ASN B N   1 
ATOM   1925 C CA  . ASN B 2 16  ? 136.506 131.071 68.563  1.00 75.96  ? 16  ASN B CA  1 
ATOM   1926 C C   . ASN B 2 16  ? 136.920 132.470 68.120  1.00 75.96  ? 16  ASN B C   1 
ATOM   1927 O O   . ASN B 2 16  ? 137.979 132.969 68.518  1.00 75.96  ? 16  ASN B O   1 
ATOM   1928 C CB  . ASN B 2 16  ? 136.856 130.042 67.488  1.00 75.96  ? 16  ASN B CB  1 
ATOM   1929 C CG  . ASN B 2 16  ? 138.278 129.531 67.609  1.00 75.96  ? 16  ASN B CG  1 
ATOM   1930 O OD1 . ASN B 2 16  ? 139.016 129.921 68.513  1.00 75.96  ? 16  ASN B OD1 1 
ATOM   1931 N ND2 . ASN B 2 16  ? 138.669 128.650 66.696  1.00 75.96  ? 16  ASN B ND2 1 
ATOM   1932 N N   . GLN B 2 17  ? 136.096 133.118 67.294  1.00 74.93  ? 17  GLN B N   1 
ATOM   1933 C CA  . GLN B 2 17  ? 136.408 134.476 66.860  1.00 74.93  ? 17  GLN B CA  1 
ATOM   1934 C C   . GLN B 2 17  ? 136.429 135.437 68.041  1.00 74.93  ? 17  GLN B C   1 
ATOM   1935 O O   . GLN B 2 17  ? 137.303 136.308 68.127  1.00 74.93  ? 17  GLN B O   1 
ATOM   1936 C CB  . GLN B 2 17  ? 135.396 134.941 65.813  1.00 74.93  ? 17  GLN B CB  1 
ATOM   1937 C CG  . GLN B 2 17  ? 135.191 136.451 65.780  1.00 74.93  ? 17  GLN B CG  1 
ATOM   1938 C CD  . GLN B 2 17  ? 134.522 136.925 64.506  1.00 74.93  ? 17  GLN B CD  1 
ATOM   1939 O OE1 . GLN B 2 17  ? 134.365 136.164 63.552  1.00 74.93  ? 17  GLN B OE1 1 
ATOM   1940 N NE2 . GLN B 2 17  ? 134.123 138.192 64.485  1.00 74.93  ? 17  GLN B NE2 1 
ATOM   1941 N N   . ILE B 2 18  ? 135.463 135.309 68.952  1.00 68.69  ? 18  ILE B N   1 
ATOM   1942 C CA  . ILE B 2 18  ? 135.441 136.179 70.125  1.00 68.69  ? 18  ILE B CA  1 
ATOM   1943 C C   . ILE B 2 18  ? 136.683 135.950 70.976  1.00 68.69  ? 18  ILE B C   1 
ATOM   1944 O O   . ILE B 2 18  ? 137.286 136.901 71.488  1.00 68.69  ? 18  ILE B O   1 
ATOM   1945 C CB  . ILE B 2 18  ? 134.148 135.963 70.932  1.00 68.69  ? 18  ILE B CB  1 
ATOM   1946 C CG1 . ILE B 2 18  ? 132.930 136.357 70.091  1.00 68.69  ? 18  ILE B CG1 1 
ATOM   1947 C CG2 . ILE B 2 18  ? 134.188 136.768 72.226  1.00 68.69  ? 18  ILE B CG2 1 
ATOM   1948 C CD1 . ILE B 2 18  ? 131.605 135.944 70.692  1.00 68.69  ? 18  ILE B CD1 1 
ATOM   1949 N N   . ARG B 2 19  ? 137.083 134.689 71.147  1.00 65.61  ? 19  ARG B N   1 
ATOM   1950 C CA  . ARG B 2 19  ? 138.297 134.400 71.903  1.00 65.61  ? 19  ARG B CA  1 
ATOM   1951 C C   . ARG B 2 19  ? 139.512 135.037 71.242  1.00 65.61  ? 19  ARG B C   1 
ATOM   1952 O O   . ARG B 2 19  ? 140.374 135.614 71.917  1.00 65.61  ? 19  ARG B O   1 
ATOM   1953 C CB  . ARG B 2 19  ? 138.489 132.889 72.028  1.00 65.61  ? 19  ARG B CB  1 
ATOM   1954 C CG  . ARG B 2 19  ? 137.551 132.219 73.012  1.00 65.61  ? 19  ARG B CG  1 
ATOM   1955 C CD  . ARG B 2 19  ? 137.832 130.729 73.100  1.00 65.61  ? 19  ARG B CD  1 
ATOM   1956 N NE  . ARG B 2 19  ? 137.071 130.085 74.162  1.00 65.61  ? 19  ARG B NE  1 
ATOM   1957 C CZ  . ARG B 2 19  ? 137.106 128.786 74.427  1.00 65.61  ? 19  ARG B CZ  1 
ATOM   1958 N NH1 . ARG B 2 19  ? 137.852 127.955 73.715  1.00 65.61  ? 19  ARG B NH1 1 
ATOM   1959 N NH2 . ARG B 2 19  ? 136.376 128.307 75.430  1.00 65.61  ? 19  ARG B NH2 1 
ATOM   1960 N N   . ASP B 2 20  ? 139.600 134.939 69.915  1.00 73.92  ? 20  ASP B N   1 
ATOM   1961 C CA  . ASP B 2 20  ? 140.736 135.519 69.208  1.00 73.92  ? 20  ASP B CA  1 
ATOM   1962 C C   . ASP B 2 20  ? 140.763 137.035 69.360  1.00 73.92  ? 20  ASP B C   1 
ATOM   1963 O O   . ASP B 2 20  ? 141.828 137.626 69.560  1.00 73.92  ? 20  ASP B O   1 
ATOM   1964 C CB  . ASP B 2 20  ? 140.690 135.126 67.733  1.00 73.92  ? 20  ASP B CB  1 
ATOM   1965 C CG  . ASP B 2 20  ? 141.056 133.673 67.507  1.00 73.92  ? 20  ASP B CG  1 
ATOM   1966 O OD1 . ASP B 2 20  ? 141.383 132.983 68.495  1.00 73.92  ? 20  ASP B OD1 1 
ATOM   1967 O OD2 . ASP B 2 20  ? 141.020 133.222 66.344  1.00 73.92  ? 20  ASP B OD2 1 
ATOM   1968 N N   . ALA B 2 21  ? 139.599 137.682 69.265  1.00 67.24  ? 21  ALA B N   1 
ATOM   1969 C CA  . ALA B 2 21  ? 139.548 139.129 69.452  1.00 67.24  ? 21  ALA B CA  1 
ATOM   1970 C C   . ALA B 2 21  ? 139.960 139.515 70.868  1.00 67.24  ? 21  ALA B C   1 
ATOM   1971 O O   . ALA B 2 21  ? 140.711 140.479 71.066  1.00 67.24  ? 21  ALA B O   1 
ATOM   1972 C CB  . ALA B 2 21  ? 138.144 139.649 69.144  1.00 67.24  ? 21  ALA B CB  1 
ATOM   1973 N N   . ARG B 2 22  ? 139.479 138.769 71.865  1.00 56.57  ? 22  ARG B N   1 
ATOM   1974 C CA  . ARG B 2 22  ? 139.851 139.056 73.246  1.00 56.57  ? 22  ARG B CA  1 
ATOM   1975 C C   . ARG B 2 22  ? 141.355 138.923 73.441  1.00 56.57  ? 22  ARG B C   1 
ATOM   1976 O O   . ARG B 2 22  ? 141.976 139.745 74.124  1.00 56.57  ? 22  ARG B O   1 
ATOM   1977 C CB  . ARG B 2 22  ? 139.101 138.122 74.195  1.00 56.57  ? 22  ARG B CB  1 
ATOM   1978 C CG  . ARG B 2 22  ? 137.635 138.476 74.390  1.00 56.57  ? 22  ARG B CG  1 
ATOM   1979 C CD  . ARG B 2 22  ? 136.959 137.534 75.375  1.00 56.57  ? 22  ARG B CD  1 
ATOM   1980 N NE  . ARG B 2 22  ? 135.574 137.911 75.633  1.00 56.57  ? 22  ARG B NE  1 
ATOM   1981 C CZ  . ARG B 2 22  ? 134.872 137.522 76.690  1.00 56.57  ? 22  ARG B CZ  1 
ATOM   1982 N NH1 . ARG B 2 22  ? 135.395 136.737 77.618  1.00 56.57  ? 22  ARG B NH1 1 
ATOM   1983 N NH2 . ARG B 2 22  ? 133.613 137.931 76.819  1.00 56.57  ? 22  ARG B NH2 1 
ATOM   1984 N N   . LYS B 2 23  ? 141.957 137.892 72.848  1.00 67.55  ? 23  LYS B N   1 
ATOM   1985 C CA  . LYS B 2 23  ? 143.408 137.751 72.915  1.00 67.55  ? 23  LYS B CA  1 
ATOM   1986 C C   . LYS B 2 23  ? 144.100 138.920 72.227  1.00 67.55  ? 23  LYS B C   1 
ATOM   1987 O O   . LYS B 2 23  ? 145.087 139.459 72.741  1.00 67.55  ? 23  LYS B O   1 
ATOM   1988 C CB  . LYS B 2 23  ? 143.830 136.422 72.286  1.00 67.55  ? 23  LYS B CB  1 
ATOM   1989 C CG  . LYS B 2 23  ? 145.295 136.034 72.492  1.00 67.55  ? 23  LYS B CG  1 
ATOM   1990 C CD  . LYS B 2 23  ? 146.244 136.813 71.589  1.00 67.55  ? 23  LYS B CD  1 
ATOM   1991 C CE  . LYS B 2 23  ? 147.587 136.116 71.457  1.00 67.55  ? 23  LYS B CE  1 
ATOM   1992 N NZ  . LYS B 2 23  ? 148.469 136.800 70.472  1.00 67.55  ? 23  LYS B NZ  1 
ATOM   1993 N N   . ALA B 2 24  ? 143.589 139.334 71.066  1.00 68.15  ? 24  ALA B N   1 
ATOM   1994 C CA  . ALA B 2 24  ? 144.229 140.406 70.311  1.00 68.15  ? 24  ALA B CA  1 
ATOM   1995 C C   . ALA B 2 24  ? 144.215 141.717 71.085  1.00 68.15  ? 24  ALA B C   1 
ATOM   1996 O O   . ALA B 2 24  ? 145.188 142.478 71.049  1.00 68.15  ? 24  ALA B O   1 
ATOM   1997 C CB  . ALA B 2 24  ? 143.536 140.578 68.961  1.00 68.15  ? 24  ALA B CB  1 
ATOM   1998 N N   . CYS B 2 25  ? 143.121 142.000 71.793  1.00 61.87  ? 25  CYS B N   1 
ATOM   1999 C CA  . CYS B 2 25  ? 142.992 143.250 72.532  1.00 61.87  ? 25  CYS B CA  1 
ATOM   2000 C C   . CYS B 2 25  ? 143.722 143.230 73.874  1.00 61.87  ? 25  CYS B C   1 
ATOM   2001 O O   . CYS B 2 25  ? 143.444 144.084 74.725  1.00 61.87  ? 25  CYS B O   1 
ATOM   2002 C CB  . CYS B 2 25  ? 141.514 143.581 72.746  1.00 61.87  ? 25  CYS B CB  1 
ATOM   2003 S SG  . CYS B 2 25  ? 140.689 144.227 71.275  1.00 61.87  ? 25  CYS B SG  1 
ATOM   2004 N N   . ALA B 2 26  ? 144.641 142.292 74.087  1.00 57.80  ? 26  ALA B N   1 
ATOM   2005 C CA  . ALA B 2 26  ? 145.421 142.206 75.314  1.00 57.80  ? 26  ALA B CA  1 
ATOM   2006 C C   . ALA B 2 26  ? 146.889 142.456 75.001  1.00 57.80  ? 26  ALA B C   1 
ATOM   2007 O O   . ALA B 2 26  ? 147.452 141.826 74.100  1.00 57.80  ? 26  ALA B O   1 
ATOM   2008 C CB  . ALA B 2 26  ? 145.249 140.838 75.978  1.00 57.80  ? 26  ALA B CB  1 
ATOM   2009 N N   . ASP B 2 27  ? 147.504 143.372 75.745  1.00 59.44  ? 27  ASP B N   1 
ATOM   2010 C CA  . ASP B 2 27  ? 148.910 143.719 75.571  1.00 59.44  ? 27  ASP B CA  1 
ATOM   2011 C C   . ASP B 2 27  ? 149.727 143.571 76.843  1.00 59.44  ? 27  ASP B C   1 
ATOM   2012 O O   . ASP B 2 27  ? 150.884 143.148 76.779  1.00 59.44  ? 27  ASP B O   1 
ATOM   2013 C CB  . ASP B 2 27  ? 149.038 145.162 75.060  1.00 59.44  ? 27  ASP B CB  1 
ATOM   2014 C CG  . ASP B 2 27  ? 148.500 146.181 76.047  1.00 59.44  ? 27  ASP B CG  1 
ATOM   2015 O OD1 . ASP B 2 27  ? 147.745 145.785 76.959  1.00 59.44  ? 27  ASP B OD1 1 
ATOM   2016 O OD2 . ASP B 2 27  ? 148.829 147.378 75.910  1.00 59.44  ? 27  ASP B OD2 1 
ATOM   2017 N N   . ALA B 2 28  ? 149.160 143.908 77.998  1.00 61.71  ? 28  ALA B N   1 
ATOM   2018 C CA  . ALA B 2 28  ? 149.880 143.817 79.258  1.00 61.71  ? 28  ALA B CA  1 
ATOM   2019 C C   . ALA B 2 28  ? 148.873 143.681 80.389  1.00 61.71  ? 28  ALA B C   1 
ATOM   2020 O O   . ALA B 2 28  ? 147.821 144.322 80.370  1.00 61.71  ? 28  ALA B O   1 
ATOM   2021 C CB  . ALA B 2 28  ? 150.770 145.044 79.480  1.00 61.71  ? 28  ALA B CB  1 
ATOM   2022 N N   . THR B 2 29  ? 149.208 142.848 81.369  1.00 59.16  ? 29  THR B N   1 
ATOM   2023 C CA  . THR B 2 29  ? 148.316 142.616 82.493  1.00 59.16  ? 29  THR B CA  1 
ATOM   2024 C C   . THR B 2 29  ? 148.253 143.841 83.398  1.00 59.16  ? 29  THR B C   1 
ATOM   2025 O O   . THR B 2 29  ? 149.179 144.656 83.444  1.00 59.16  ? 29  THR B O   1 
ATOM   2026 C CB  . THR B 2 29  ? 148.777 141.404 83.300  1.00 59.16  ? 29  THR B CB  1 
ATOM   2027 O OG1 . THR B 2 29  ? 150.106 141.632 83.787  1.00 59.16  ? 29  THR B OG1 1 
ATOM   2028 C CG2 . THR B 2 29  ? 148.759 140.148 82.441  1.00 59.16  ? 29  THR B CG2 1 
ATOM   2029 N N   . LEU B 2 30  ? 147.142 143.961 84.128  1.00 45.84  ? 30  LEU B N   1 
ATOM   2030 C CA  . LEU B 2 30  ? 146.987 145.072 85.060  1.00 45.84  ? 30  LEU B CA  1 
ATOM   2031 C C   . LEU B 2 30  ? 148.115 145.102 86.082  1.00 45.84  ? 30  LEU B C   1 
ATOM   2032 O O   . LEU B 2 30  ? 148.463 146.174 86.591  1.00 45.84  ? 30  LEU B O   1 
ATOM   2033 C CB  . LEU B 2 30  ? 145.631 144.976 85.762  1.00 45.84  ? 30  LEU B CB  1 
ATOM   2034 C CG  . LEU B 2 30  ? 145.372 145.911 86.947  1.00 45.84  ? 30  LEU B CG  1 
ATOM   2035 C CD1 . LEU B 2 30  ? 145.422 147.361 86.513  1.00 45.84  ? 30  LEU B CD1 1 
ATOM   2036 C CD2 . LEU B 2 30  ? 144.030 145.596 87.585  1.00 45.84  ? 30  LEU B CD2 1 
ATOM   2037 N N   . SER B 2 31  ? 148.694 143.942 86.398  1.00 55.64  ? 31  SER B N   1 
ATOM   2038 C CA  . SER B 2 31  ? 149.799 143.908 87.350  1.00 55.64  ? 31  SER B CA  1 
ATOM   2039 C C   . SER B 2 31  ? 150.988 144.711 86.841  1.00 55.64  ? 31  SER B C   1 
ATOM   2040 O O   . SER B 2 31  ? 151.594 145.483 87.594  1.00 55.64  ? 31  SER B O   1 
ATOM   2041 C CB  . SER B 2 31  ? 150.207 142.461 87.624  1.00 55.64  ? 31  SER B CB  1 
ATOM   2042 O OG  . SER B 2 31  ? 149.106 141.702 88.092  1.00 55.64  ? 31  SER B OG  1 
ATOM   2043 N N   . GLN B 2 32  ? 151.337 144.548 85.563  1.00 63.15  ? 32  GLN B N   1 
ATOM   2044 C CA  . GLN B 2 32  ? 152.469 145.282 85.010  1.00 63.15  ? 32  GLN B CA  1 
ATOM   2045 C C   . GLN B 2 32  ? 152.218 146.785 85.039  1.00 63.15  ? 32  GLN B C   1 
ATOM   2046 O O   . GLN B 2 32  ? 153.122 147.567 85.353  1.00 63.15  ? 32  GLN B O   1 
ATOM   2047 C CB  . GLN B 2 32  ? 152.755 144.805 83.587  1.00 63.15  ? 32  GLN B CB  1 
ATOM   2048 C CG  . GLN B 2 32  ? 153.365 143.410 83.528  1.00 63.15  ? 32  GLN B CG  1 
ATOM   2049 C CD  . GLN B 2 32  ? 152.825 142.569 82.385  1.00 63.15  ? 32  GLN B CD  1 
ATOM   2050 O OE1 . GLN B 2 32  ? 152.001 143.024 81.593  1.00 63.15  ? 32  GLN B OE1 1 
ATOM   2051 N NE2 . GLN B 2 32  ? 153.289 141.328 82.298  1.00 63.15  ? 32  GLN B NE2 1 
ATOM   2052 N N   . ILE B 2 33  ? 150.995 147.209 84.715  1.00 55.33  ? 33  ILE B N   1 
ATOM   2053 C CA  . ILE B 2 33  ? 150.652 148.625 84.813  1.00 55.33  ? 33  ILE B CA  1 
ATOM   2054 C C   . ILE B 2 33  ? 150.755 149.091 86.258  1.00 55.33  ? 33  ILE B C   1 
ATOM   2055 O O   . ILE B 2 33  ? 151.253 150.187 86.540  1.00 55.33  ? 33  ILE B O   1 
ATOM   2056 C CB  . ILE B 2 33  ? 149.248 148.879 84.234  1.00 55.33  ? 33  ILE B CB  1 
ATOM   2057 C CG1 . ILE B 2 33  ? 149.181 148.455 82.764  1.00 55.33  ? 33  ILE B CG1 1 
ATOM   2058 C CG2 . ILE B 2 33  ? 148.868 150.344 84.386  1.00 55.33  ? 33  ILE B CG2 1 
ATOM   2059 C CD1 . ILE B 2 33  ? 150.095 149.241 81.843  1.00 55.33  ? 33  ILE B CD1 1 
ATOM   2060 N N   . THR B 2 34  ? 150.292 148.263 87.197  1.00 52.80  ? 34  THR B N   1 
ATOM   2061 C CA  . THR B 2 34  ? 150.354 148.561 88.622  1.00 52.80  ? 34  THR B CA  1 
ATOM   2062 C C   . THR B 2 34  ? 151.625 148.027 89.269  1.00 52.80  ? 34  THR B C   1 
ATOM   2063 O O   . THR B 2 34  ? 151.615 147.672 90.456  1.00 52.80  ? 34  THR B O   1 
ATOM   2064 C CB  . THR B 2 34  ? 149.124 147.993 89.332  1.00 52.80  ? 34  THR B CB  1 
ATOM   2065 O OG1 . THR B 2 34  ? 148.953 146.618 88.969  1.00 52.80  ? 34  THR B OG1 1 
ATOM   2066 C CG2 . THR B 2 34  ? 147.876 148.775 88.955  1.00 52.80  ? 34  THR B CG2 1 
ATOM   2067 N N   . ASN B 2 35  ? 152.721 147.953 88.513  1.00 60.22  ? 35  ASN B N   1 
ATOM   2068 C CA  . ASN B 2 35  ? 153.942 147.349 89.030  1.00 60.22  ? 35  ASN B CA  1 
ATOM   2069 C C   . ASN B 2 35  ? 154.481 148.119 90.230  1.00 60.22  ? 35  ASN B C   1 
ATOM   2070 O O   . ASN B 2 35  ? 154.956 147.513 91.198  1.00 60.22  ? 35  ASN B O   1 
ATOM   2071 C CB  . ASN B 2 35  ? 154.990 147.279 87.918  1.00 60.22  ? 35  ASN B CB  1 
ATOM   2072 C CG  . ASN B 2 35  ? 156.286 146.623 88.365  1.00 60.22  ? 35  ASN B CG  1 
ATOM   2073 O OD1 . ASN B 2 35  ? 156.802 146.903 89.446  1.00 60.22  ? 35  ASN B OD1 1 
ATOM   2074 N ND2 . ASN B 2 35  ? 156.818 145.743 87.526  1.00 60.22  ? 35  ASN B ND2 1 
ATOM   2075 N N   . ASN B 2 36  ? 154.417 149.448 90.191  1.00 63.19  ? 36  ASN B N   1 
ATOM   2076 C CA  . ASN B 2 36  ? 155.077 150.297 91.181  1.00 63.19  ? 36  ASN B CA  1 
ATOM   2077 C C   . ASN B 2 36  ? 154.098 151.305 91.773  1.00 63.19  ? 36  ASN B C   1 
ATOM   2078 O O   . ASN B 2 36  ? 154.373 152.505 91.851  1.00 63.19  ? 36  ASN B O   1 
ATOM   2079 C CB  . ASN B 2 36  ? 156.273 151.007 90.554  1.00 63.19  ? 36  ASN B CB  1 
ATOM   2080 C CG  . ASN B 2 36  ? 157.526 150.152 90.559  1.00 63.19  ? 36  ASN B CG  1 
ATOM   2081 O OD1 . ASN B 2 36  ? 157.711 149.302 91.430  1.00 63.19  ? 36  ASN B OD1 1 
ATOM   2082 N ND2 . ASN B 2 36  ? 158.396 150.372 89.580  1.00 63.19  ? 36  ASN B ND2 1 
ATOM   2083 N N   . ILE B 2 37  ? 152.931 150.830 92.202  1.00 50.46  ? 37  ILE B N   1 
ATOM   2084 C CA  . ILE B 2 37  ? 151.982 151.671 92.924  1.00 50.46  ? 37  ILE B CA  1 
ATOM   2085 C C   . ILE B 2 37  ? 152.294 151.605 94.414  1.00 50.46  ? 37  ILE B C   1 
ATOM   2086 O O   . ILE B 2 37  ? 153.045 150.734 94.864  1.00 50.46  ? 37  ILE B O   1 
ATOM   2087 C CB  . ILE B 2 37  ? 150.527 151.255 92.642  1.00 50.46  ? 37  ILE B CB  1 
ATOM   2088 C CG1 . ILE B 2 37  ? 149.584 152.433 92.903  1.00 50.46  ? 37  ILE B CG1 1 
ATOM   2089 C CG2 . ILE B 2 37  ? 150.130 150.062 93.501  1.00 50.46  ? 37  ILE B CG2 1 
ATOM   2090 C CD1 . ILE B 2 37  ? 148.225 152.273 92.272  1.00 50.46  ? 37  ILE B CD1 1 
ATOM   2091 N N   . ASP B 2 38  ? 151.725 152.525 95.184  1.00 56.83  ? 38  ASP B N   1 
ATOM   2092 C CA  . ASP B 2 38  ? 151.954 152.555 96.624  1.00 56.83  ? 38  ASP B CA  1 
ATOM   2093 C C   . ASP B 2 38  ? 151.150 151.454 97.306  1.00 56.83  ? 38  ASP B C   1 
ATOM   2094 O O   . ASP B 2 38  ? 149.923 151.426 97.166  1.00 56.83  ? 38  ASP B O   1 
ATOM   2095 C CB  . ASP B 2 38  ? 151.555 153.910 97.195  1.00 56.83  ? 38  ASP B CB  1 
ATOM   2096 C CG  . ASP B 2 38  ? 152.416 155.040 96.671  1.00 56.83  ? 38  ASP B CG  1 
ATOM   2097 O OD1 . ASP B 2 38  ? 153.612 154.804 96.405  1.00 56.83  ? 38  ASP B OD1 1 
ATOM   2098 O OD2 . ASP B 2 38  ? 151.893 156.165 96.526  1.00 56.83  ? 38  ASP B OD2 1 
ATOM   2099 N N   . PRO B 2 39  ? 151.782 150.537 98.041  1.00 41.34  ? 39  PRO B N   1 
ATOM   2100 C CA  . PRO B 2 39  ? 151.003 149.575 98.827  1.00 41.34  ? 39  PRO B CA  1 
ATOM   2101 C C   . PRO B 2 39  ? 150.144 150.286 99.863  1.00 41.34  ? 39  PRO B C   1 
ATOM   2102 O O   . PRO B 2 39  ? 150.558 151.281 100.461 1.00 41.34  ? 39  PRO B O   1 
ATOM   2103 C CB  . PRO B 2 39  ? 152.073 148.696 99.484  1.00 41.34  ? 39  PRO B CB  1 
ATOM   2104 C CG  . PRO B 2 39  ? 153.286 148.871 98.646  1.00 41.34  ? 39  PRO B CG  1 
ATOM   2105 C CD  . PRO B 2 39  ? 153.228 150.265 98.117  1.00 41.34  ? 39  PRO B CD  1 
ATOM   2106 N N   . VAL B 2 40  ? 148.935 149.762 100.074 1.00 31.08  ? 40  VAL B N   1 
ATOM   2107 C CA  . VAL B 2 40  ? 148.012 150.400 101.008 1.00 31.08  ? 40  VAL B CA  1 
ATOM   2108 C C   . VAL B 2 40  ? 148.494 150.230 102.443 1.00 31.08  ? 40  VAL B C   1 
ATOM   2109 O O   . VAL B 2 40  ? 148.387 151.153 103.259 1.00 31.08  ? 40  VAL B O   1 
ATOM   2110 C CB  . VAL B 2 40  ? 146.588 149.847 100.820 1.00 31.08  ? 40  VAL B CB  1 
ATOM   2111 C CG1 . VAL B 2 40  ? 146.084 150.148 99.422  1.00 31.08  ? 40  VAL B CG1 1 
ATOM   2112 C CG2 . VAL B 2 40  ? 146.542 148.351 101.100 1.00 31.08  ? 40  VAL B CG2 1 
ATOM   2113 N N   . GLY B 2 41  ? 149.026 149.060 102.774 1.00 37.14  ? 41  GLY B N   1 
ATOM   2114 C CA  . GLY B 2 41  ? 149.446 148.766 104.127 1.00 37.14  ? 41  GLY B CA  1 
ATOM   2115 C C   . GLY B 2 41  ? 148.367 148.052 104.925 1.00 37.14  ? 41  GLY B C   1 
ATOM   2116 O O   . GLY B 2 41  ? 147.191 148.032 104.567 1.00 37.14  ? 41  GLY B O   1 
ATOM   2117 N N   . ARG B 2 42  ? 148.792 147.457 106.036 1.00 34.91  ? 42  ARG B N   1 
ATOM   2118 C CA  . ARG B 2 42  ? 147.875 146.682 106.860 1.00 34.91  ? 42  ARG B CA  1 
ATOM   2119 C C   . ARG B 2 42  ? 146.704 147.543 107.313 1.00 34.91  ? 42  ARG B C   1 
ATOM   2120 O O   . ARG B 2 42  ? 146.879 148.686 107.743 1.00 34.91  ? 42  ARG B O   1 
ATOM   2121 C CB  . ARG B 2 42  ? 148.609 146.113 108.074 1.00 34.91  ? 42  ARG B CB  1 
ATOM   2122 C CG  . ARG B 2 42  ? 147.859 144.991 108.778 1.00 34.91  ? 42  ARG B CG  1 
ATOM   2123 C CD  . ARG B 2 42  ? 148.805 143.895 109.247 1.00 34.91  ? 42  ARG B CD  1 
ATOM   2124 N NE  . ARG B 2 42  ? 149.339 143.121 108.131 1.00 34.91  ? 42  ARG B NE  1 
ATOM   2125 C CZ  . ARG B 2 42  ? 148.759 142.048 107.608 1.00 34.91  ? 42  ARG B CZ  1 
ATOM   2126 N NH1 . ARG B 2 42  ? 147.610 141.584 108.074 1.00 34.91  ? 42  ARG B NH1 1 
ATOM   2127 N NH2 . ARG B 2 42  ? 149.343 141.427 106.589 1.00 34.91  ? 42  ARG B NH2 1 
ATOM   2128 N N   . ILE B 2 43  ? 145.501 146.983 107.214 1.00 28.38  ? 43  ILE B N   1 
ATOM   2129 C CA  . ILE B 2 43  ? 144.266 147.654 107.603 1.00 28.38  ? 43  ILE B CA  1 
ATOM   2130 C C   . ILE B 2 43  ? 143.802 147.055 108.922 1.00 28.38  ? 43  ILE B C   1 
ATOM   2131 O O   . ILE B 2 43  ? 143.751 145.828 109.068 1.00 28.38  ? 43  ILE B O   1 
ATOM   2132 C CB  . ILE B 2 43  ? 143.180 147.514 106.522 1.00 28.38  ? 43  ILE B CB  1 
ATOM   2133 C CG1 . ILE B 2 43  ? 143.713 147.963 105.158 1.00 28.38  ? 43  ILE B CG1 1 
ATOM   2134 C CG2 . ILE B 2 43  ? 141.951 148.319 106.897 1.00 28.38  ? 43  ILE B CG2 1 
ATOM   2135 C CD1 . ILE B 2 43  ? 144.132 149.414 105.100 1.00 28.38  ? 43  ILE B CD1 1 
ATOM   2136 N N   . GLN B 2 44  ? 143.457 147.917 109.877 1.00 28.20  ? 44  GLN B N   1 
ATOM   2137 C CA  . GLN B 2 44  ? 143.134 147.471 111.226 1.00 28.20  ? 44  GLN B CA  1 
ATOM   2138 C C   . GLN B 2 44  ? 141.752 147.942 111.655 1.00 28.20  ? 44  GLN B C   1 
ATOM   2139 O O   . GLN B 2 44  ? 141.587 148.453 112.767 1.00 28.20  ? 44  GLN B O   1 
ATOM   2140 C CB  . GLN B 2 44  ? 144.178 147.979 112.224 1.00 28.20  ? 44  GLN B CB  1 
ATOM   2141 C CG  . GLN B 2 44  ? 145.626 147.661 111.860 1.00 28.20  ? 44  GLN B CG  1 
ATOM   2142 C CD  . GLN B 2 44  ? 146.174 146.454 112.601 1.00 28.20  ? 44  GLN B CD  1 
ATOM   2143 O OE1 . GLN B 2 44  ? 145.616 146.017 113.607 1.00 28.20  ? 44  GLN B OE1 1 
ATOM   2144 N NE2 . GLN B 2 44  ? 147.283 145.916 112.109 1.00 28.20  ? 44  GLN B NE2 1 
ATOM   2145 N N   . MET B 2 45  ? 140.754 147.782 110.792 1.00 22.08  ? 45  MET B N   1 
ATOM   2146 C CA  . MET B 2 45  ? 139.405 148.190 111.152 1.00 22.08  ? 45  MET B CA  1 
ATOM   2147 C C   . MET B 2 45  ? 138.902 147.359 112.326 1.00 22.08  ? 45  MET B C   1 
ATOM   2148 O O   . MET B 2 45  ? 139.237 146.181 112.471 1.00 22.08  ? 45  MET B O   1 
ATOM   2149 C CB  . MET B 2 45  ? 138.462 148.041 109.959 1.00 22.08  ? 45  MET B CB  1 
ATOM   2150 C CG  . MET B 2 45  ? 138.591 149.159 108.935 1.00 22.08  ? 45  MET B CG  1 
ATOM   2151 S SD  . MET B 2 45  ? 137.853 148.794 107.330 1.00 22.08  ? 45  MET B SD  1 
ATOM   2152 C CE  . MET B 2 45  ? 136.634 147.557 107.761 1.00 22.08  ? 45  MET B CE  1 
ATOM   2153 N N   . ARG B 2 46  ? 138.092 147.988 113.175 1.00 21.71  ? 46  ARG B N   1 
ATOM   2154 C CA  . ARG B 2 46  ? 137.576 147.346 114.374 1.00 21.71  ? 46  ARG B CA  1 
ATOM   2155 C C   . ARG B 2 46  ? 136.092 147.645 114.514 1.00 21.71  ? 46  ARG B C   1 
ATOM   2156 O O   . ARG B 2 46  ? 135.597 148.655 114.012 1.00 21.71  ? 46  ARG B O   1 
ATOM   2157 C CB  . ARG B 2 46  ? 138.322 147.816 115.625 1.00 21.71  ? 46  ARG B CB  1 
ATOM   2158 C CG  . ARG B 2 46  ? 139.809 147.520 115.599 1.00 21.71  ? 46  ARG B CG  1 
ATOM   2159 C CD  . ARG B 2 46  ? 140.482 147.944 116.891 1.00 21.71  ? 46  ARG B CD  1 
ATOM   2160 N NE  . ARG B 2 46  ? 141.764 147.277 117.083 1.00 21.71  ? 46  ARG B NE  1 
ATOM   2161 C CZ  . ARG B 2 46  ? 142.889 147.622 116.473 1.00 21.71  ? 46  ARG B CZ  1 
ATOM   2162 N NH1 . ARG B 2 46  ? 142.932 148.628 115.613 1.00 21.71  ? 46  ARG B NH1 1 
ATOM   2163 N NH2 . ARG B 2 46  ? 144.002 146.940 116.730 1.00 21.71  ? 46  ARG B NH2 1 
ATOM   2164 N N   . THR B 2 47  ? 135.389 146.756 115.211 1.00 15.82  ? 47  THR B N   1 
ATOM   2165 C CA  . THR B 2 47  ? 133.953 146.915 115.392 1.00 15.82  ? 47  THR B CA  1 
ATOM   2166 C C   . THR B 2 47  ? 133.654 148.180 116.187 1.00 15.82  ? 47  THR B C   1 
ATOM   2167 O O   . THR B 2 47  ? 134.466 148.641 116.992 1.00 15.82  ? 47  THR B O   1 
ATOM   2168 C CB  . THR B 2 47  ? 133.369 145.701 116.111 1.00 15.82  ? 47  THR B CB  1 
ATOM   2169 O OG1 . THR B 2 47  ? 133.842 144.502 115.490 1.00 15.82  ? 47  THR B OG1 1 
ATOM   2170 C CG2 . THR B 2 47  ? 131.853 145.724 116.058 1.00 15.82  ? 47  THR B CG2 1 
ATOM   2171 N N   . ARG B 2 48  ? 132.475 148.749 115.944 1.00 17.75  ? 48  ARG B N   1 
ATOM   2172 C CA  . ARG B 2 48  ? 132.067 149.971 116.624 1.00 17.75  ? 48  ARG B CA  1 
ATOM   2173 C C   . ARG B 2 48  ? 130.670 149.837 117.210 1.00 17.75  ? 48  ARG B C   1 
ATOM   2174 O O   . ARG B 2 48  ? 130.338 150.512 118.188 1.00 17.75  ? 48  ARG B O   1 
ATOM   2175 C CB  . ARG B 2 48  ? 132.119 151.154 115.662 1.00 17.75  ? 48  ARG B CB  1 
ATOM   2176 C CG  . ARG B 2 48  ? 133.483 151.386 115.046 1.00 17.75  ? 48  ARG B CG  1 
ATOM   2177 C CD  . ARG B 2 48  ? 134.489 151.848 116.079 1.00 17.75  ? 48  ARG B CD  1 
ATOM   2178 N NE  . ARG B 2 48  ? 135.770 152.189 115.475 1.00 17.75  ? 48  ARG B NE  1 
ATOM   2179 C CZ  . ARG B 2 48  ? 136.928 152.194 116.121 1.00 17.75  ? 48  ARG B CZ  1 
ATOM   2180 N NH1 . ARG B 2 48  ? 137.005 151.889 117.407 1.00 17.75  ? 48  ARG B NH1 1 
ATOM   2181 N NH2 . ARG B 2 48  ? 138.038 152.511 115.461 1.00 17.75  ? 48  ARG B NH2 1 
ATOM   2182 N N   . ARG B 2 49  ? 129.843 148.977 116.620 1.00 16.84  ? 49  ARG B N   1 
ATOM   2183 C CA  . ARG B 2 49  ? 128.479 148.774 117.081 1.00 16.84  ? 49  ARG B CA  1 
ATOM   2184 C C   . ARG B 2 49  ? 128.146 147.292 117.022 1.00 16.84  ? 49  ARG B C   1 
ATOM   2185 O O   . ARG B 2 49  ? 128.924 146.475 116.526 1.00 16.84  ? 49  ARG B O   1 
ATOM   2186 C CB  . ARG B 2 49  ? 127.470 149.566 116.240 1.00 16.84  ? 49  ARG B CB  1 
ATOM   2187 C CG  . ARG B 2 49  ? 127.536 151.069 116.422 1.00 16.84  ? 49  ARG B CG  1 
ATOM   2188 C CD  . ARG B 2 49  ? 126.734 151.520 117.624 1.00 16.84  ? 49  ARG B CD  1 
ATOM   2189 N NE  . ARG B 2 49  ? 126.538 152.963 117.633 1.00 16.84  ? 49  ARG B NE  1 
ATOM   2190 C CZ  . ARG B 2 49  ? 127.499 153.852 117.842 1.00 16.84  ? 49  ARG B CZ  1 
ATOM   2191 N NH1 . ARG B 2 49  ? 128.748 153.480 118.071 1.00 16.84  ? 49  ARG B NH1 1 
ATOM   2192 N NH2 . ARG B 2 49  ? 127.200 155.148 117.820 1.00 16.84  ? 49  ARG B NH2 1 
ATOM   2193 N N   . THR B 2 50  ? 126.974 146.953 117.546 1.00 15.19  ? 50  THR B N   1 
ATOM   2194 C CA  . THR B 2 50  ? 126.435 145.601 117.422 1.00 15.19  ? 50  THR B CA  1 
ATOM   2195 C C   . THR B 2 50  ? 124.944 145.680 117.699 1.00 15.19  ? 50  THR B C   1 
ATOM   2196 O O   . THR B 2 50  ? 124.543 146.116 118.782 1.00 15.19  ? 50  THR B O   1 
ATOM   2197 C CB  . THR B 2 50  ? 127.114 144.633 118.384 1.00 15.19  ? 50  THR B CB  1 
ATOM   2198 O OG1 . THR B 2 50  ? 128.524 144.620 118.138 1.00 15.19  ? 50  THR B OG1 1 
ATOM   2199 C CG2 . THR B 2 50  ? 126.562 143.230 118.203 1.00 15.19  ? 50  THR B CG2 1 
ATOM   2200 N N   . LEU B 2 51  ? 124.132 145.268 116.733 1.00 14.48  ? 51  LEU B N   1 
ATOM   2201 C CA  . LEU B 2 51  ? 122.685 145.377 116.826 1.00 14.48  ? 51  LEU B CA  1 
ATOM   2202 C C   . LEU B 2 51  ? 122.091 144.019 117.166 1.00 14.48  ? 51  LEU B C   1 
ATOM   2203 O O   . LEU B 2 51  ? 122.458 143.007 116.561 1.00 14.48  ? 51  LEU B O   1 
ATOM   2204 C CB  . LEU B 2 51  ? 122.099 145.903 115.516 1.00 14.48  ? 51  LEU B CB  1 
ATOM   2205 C CG  . LEU B 2 51  ? 122.897 147.022 114.846 1.00 14.48  ? 51  LEU B CG  1 
ATOM   2206 C CD1 . LEU B 2 51  ? 122.165 147.534 113.626 1.00 14.48  ? 51  LEU B CD1 1 
ATOM   2207 C CD2 . LEU B 2 51  ? 123.161 148.154 115.818 1.00 14.48  ? 51  LEU B CD2 1 
ATOM   2208 N N   . ARG B 2 52  ? 121.179 144.000 118.133 1.00 17.89  ? 52  ARG B N   1 
ATOM   2209 C CA  . ARG B 2 52  ? 120.554 142.774 118.599 1.00 17.89  ? 52  ARG B CA  1 
ATOM   2210 C C   . ARG B 2 52  ? 119.042 142.924 118.553 1.00 17.89  ? 52  ARG B C   1 
ATOM   2211 O O   . ARG B 2 52  ? 118.508 144.029 118.677 1.00 17.89  ? 52  ARG B O   1 
ATOM   2212 C CB  . ARG B 2 52  ? 120.997 142.433 120.022 1.00 17.89  ? 52  ARG B CB  1 
ATOM   2213 C CG  . ARG B 2 52  ? 122.489 142.580 120.250 1.00 17.89  ? 52  ARG B CG  1 
ATOM   2214 C CD  . ARG B 2 52  ? 122.900 142.046 121.609 1.00 17.89  ? 52  ARG B CD  1 
ATOM   2215 N NE  . ARG B 2 52  ? 124.300 141.643 121.631 1.00 17.89  ? 52  ARG B NE  1 
ATOM   2216 C CZ  . ARG B 2 52  ? 125.323 142.487 121.683 1.00 17.89  ? 52  ARG B CZ  1 
ATOM   2217 N NH1 . ARG B 2 52  ? 125.138 143.796 121.728 1.00 17.89  ? 52  ARG B NH1 1 
ATOM   2218 N NH2 . ARG B 2 52  ? 126.561 142.004 121.689 1.00 17.89  ? 52  ARG B NH2 1 
ATOM   2219 N N   . GLY B 2 53  ? 118.355 141.798 118.383 1.00 16.82  ? 53  GLY B N   1 
ATOM   2220 C CA  . GLY B 2 53  ? 116.909 141.803 118.304 1.00 16.82  ? 53  GLY B CA  1 
ATOM   2221 C C   . GLY B 2 53  ? 116.360 140.800 117.312 1.00 16.82  ? 53  GLY B C   1 
ATOM   2222 O O   . GLY B 2 53  ? 115.218 140.353 117.447 1.00 16.82  ? 53  GLY B O   1 
ATOM   2223 N N   . HIS B 2 54  ? 117.156 140.439 116.313 1.00 14.43  ? 54  HIS B N   1 
ATOM   2224 C CA  . HIS B 2 54  ? 116.750 139.414 115.366 1.00 14.43  ? 54  HIS B CA  1 
ATOM   2225 C C   . HIS B 2 54  ? 116.848 138.036 116.004 1.00 14.43  ? 54  HIS B C   1 
ATOM   2226 O O   . HIS B 2 54  ? 117.724 137.771 116.831 1.00 14.43  ? 54  HIS B O   1 
ATOM   2227 C CB  . HIS B 2 54  ? 117.615 139.470 114.107 1.00 14.43  ? 54  HIS B CB  1 
ATOM   2228 C CG  . HIS B 2 54  ? 117.068 140.364 113.039 1.00 14.43  ? 54  HIS B CG  1 
ATOM   2229 N ND1 . HIS B 2 54  ? 115.781 140.250 112.561 1.00 14.43  ? 54  HIS B ND1 1 
ATOM   2230 C CD2 . HIS B 2 54  ? 117.635 141.386 112.354 1.00 14.43  ? 54  HIS B CD2 1 
ATOM   2231 C CE1 . HIS B 2 54  ? 115.578 141.163 111.630 1.00 14.43  ? 54  HIS B CE1 1 
ATOM   2232 N NE2 . HIS B 2 54  ? 116.686 141.865 111.485 1.00 14.43  ? 54  HIS B NE2 1 
ATOM   2233 N N   . LEU B 2 55  ? 115.935 137.150 115.608 1.00 17.20  ? 55  LEU B N   1 
ATOM   2234 C CA  . LEU B 2 55  ? 115.875 135.807 116.172 1.00 17.20  ? 55  LEU B CA  1 
ATOM   2235 C C   . LEU B 2 55  ? 116.626 134.789 115.318 1.00 17.20  ? 55  LEU B C   1 
ATOM   2236 O O   . LEU B 2 55  ? 117.404 133.989 115.846 1.00 17.20  ? 55  LEU B O   1 
ATOM   2237 C CB  . LEU B 2 55  ? 114.416 135.376 116.336 1.00 17.20  ? 55  LEU B CB  1 
ATOM   2238 C CG  . LEU B 2 55  ? 113.594 136.187 117.336 1.00 17.20  ? 55  LEU B CG  1 
ATOM   2239 C CD1 . LEU B 2 55  ? 112.122 135.848 117.212 1.00 17.20  ? 55  LEU B CD1 1 
ATOM   2240 C CD2 . LEU B 2 55  ? 114.079 135.943 118.750 1.00 17.20  ? 55  LEU B CD2 1 
ATOM   2241 N N   . ALA B 2 56  ? 116.407 134.805 114.009 1.00 17.09  ? 56  ALA B N   1 
ATOM   2242 C CA  . ALA B 2 56  ? 116.996 133.842 113.091 1.00 17.09  ? 56  ALA B CA  1 
ATOM   2243 C C   . ALA B 2 56  ? 118.107 134.499 112.282 1.00 17.09  ? 56  ALA B C   1 
ATOM   2244 O O   . ALA B 2 56  ? 118.435 135.674 112.461 1.00 17.09  ? 56  ALA B O   1 
ATOM   2245 C CB  . ALA B 2 56  ? 115.924 133.256 112.172 1.00 17.09  ? 56  ALA B CB  1 
ATOM   2246 N N   . LYS B 2 57  ? 118.692 133.718 111.378 1.00 28.35  ? 57  LYS B N   1 
ATOM   2247 C CA  . LYS B 2 57  ? 119.809 134.199 110.579 1.00 28.35  ? 57  LYS B CA  1 
ATOM   2248 C C   . LYS B 2 57  ? 119.360 135.275 109.598 1.00 28.35  ? 57  LYS B C   1 
ATOM   2249 O O   . LYS B 2 57  ? 118.196 135.342 109.200 1.00 28.35  ? 57  LYS B O   1 
ATOM   2250 C CB  . LYS B 2 57  ? 120.463 133.037 109.835 1.00 28.35  ? 57  LYS B CB  1 
ATOM   2251 C CG  . LYS B 2 57  ? 119.554 132.278 108.895 1.00 28.35  ? 57  LYS B CG  1 
ATOM   2252 C CD  . LYS B 2 57  ? 120.317 131.125 108.265 1.00 28.35  ? 57  LYS B CD  1 
ATOM   2253 C CE  . LYS B 2 57  ? 119.423 130.176 107.494 1.00 28.35  ? 57  LYS B CE  1 
ATOM   2254 N NZ  . LYS B 2 57  ? 118.102 129.938 108.136 1.00 28.35  ? 57  LYS B NZ  1 
ATOM   2255 N N   . ILE B 2 58  ? 120.309 136.123 109.210 1.00 13.74  ? 58  ILE B N   1 
ATOM   2256 C CA  . ILE B 2 58  ? 120.053 137.300 108.388 1.00 13.74  ? 58  ILE B CA  1 
ATOM   2257 C C   . ILE B 2 58  ? 120.578 137.037 106.982 1.00 13.74  ? 58  ILE B C   1 
ATOM   2258 O O   . ILE B 2 58  ? 121.739 136.648 106.810 1.00 13.74  ? 58  ILE B O   1 
ATOM   2259 C CB  . ILE B 2 58  ? 120.710 138.551 108.994 1.00 13.74  ? 58  ILE B CB  1 
ATOM   2260 C CG1 . ILE B 2 58  ? 119.987 138.964 110.274 1.00 13.74  ? 58  ILE B CG1 1 
ATOM   2261 C CG2 . ILE B 2 58  ? 120.706 139.694 107.995 1.00 13.74  ? 58  ILE B CG2 1 
ATOM   2262 C CD1 . ILE B 2 58  ? 120.813 139.834 111.183 1.00 13.74  ? 58  ILE B CD1 1 
ATOM   2263 N N   . TYR B 2 59  ? 119.717 137.341 105.998 1.00 13.74  ? 59  TYR B N   1 
ATOM   2264 C CA  . TYR B 2 59  ? 120.034 137.071 104.574 1.00 13.74  ? 59  TYR B CA  1 
ATOM   2265 C C   . TYR B 2 59  ? 120.357 138.360 103.793 1.00 13.74  ? 59  TYR B C   1 
ATOM   2266 O O   . TYR B 2 59  ? 121.094 138.245 102.795 1.00 13.74  ? 59  TYR B O   1 
ATOM   2267 C CB  . TYR B 2 59  ? 118.840 136.341 103.959 1.00 13.74  ? 59  TYR B CB  1 
ATOM   2268 C CG  . TYR B 2 59  ? 119.104 134.928 103.506 1.00 13.74  ? 59  TYR B CG  1 
ATOM   2269 C CD1 . TYR B 2 59  ? 119.303 133.908 104.421 1.00 13.74  ? 59  TYR B CD1 1 
ATOM   2270 C CD2 . TYR B 2 59  ? 119.137 134.607 102.161 1.00 13.74  ? 59  TYR B CD2 1 
ATOM   2271 C CE1 . TYR B 2 59  ? 119.540 132.607 104.011 1.00 13.74  ? 59  TYR B CE1 1 
ATOM   2272 C CE2 . TYR B 2 59  ? 119.372 133.312 101.733 1.00 13.74  ? 59  TYR B CE2 1 
ATOM   2273 C CZ  . TYR B 2 59  ? 119.575 132.308 102.662 1.00 13.74  ? 59  TYR B CZ  1 
ATOM   2274 O OH  . TYR B 2 59  ? 119.809 131.029 102.247 1.00 13.74  ? 59  TYR B OH  1 
ATOM   2275 N N   . ALA B 2 60  ? 119.835 139.530 104.194 1.00 12.93  ? 60  ALA B N   1 
ATOM   2276 C CA  . ALA B 2 60  ? 120.094 140.740 103.436 1.00 12.93  ? 60  ALA B CA  1 
ATOM   2277 C C   . ALA B 2 60  ? 119.893 141.955 104.319 1.00 12.93  ? 60  ALA B C   1 
ATOM   2278 O O   . ALA B 2 60  ? 118.994 141.989 105.161 1.00 12.93  ? 60  ALA B O   1 
ATOM   2279 C CB  . ALA B 2 60  ? 119.188 140.827 102.205 1.00 12.93  ? 60  ALA B CB  1 
ATOM   2280 N N   . MET B 2 61  ? 120.753 142.945 104.114 1.00 10.94  ? 61  MET B N   1 
ATOM   2281 C CA  . MET B 2 61  ? 120.601 144.260 104.708 1.00 10.94  ? 61  MET B CA  1 
ATOM   2282 C C   . MET B 2 61  ? 120.874 145.290 103.627 1.00 10.94  ? 61  MET B C   1 
ATOM   2283 O O   . MET B 2 61  ? 121.707 145.071 102.744 1.00 10.94  ? 61  MET B O   1 
ATOM   2284 C CB  . MET B 2 61  ? 121.556 144.470 105.889 1.00 10.94  ? 61  MET B CB  1 
ATOM   2285 C CG  . MET B 2 61  ? 123.025 144.231 105.567 1.00 10.94  ? 61  MET B CG  1 
ATOM   2286 S SD  . MET B 2 61  ? 123.844 145.600 104.727 1.00 10.94  ? 61  MET B SD  1 
ATOM   2287 C CE  . MET B 2 61  ? 123.606 146.931 105.896 1.00 10.94  ? 61  MET B CE  1 
ATOM   2288 N N   . HIS B 2 62  ? 120.164 146.410 103.695 1.00 11.44  ? 62  HIS B N   1 
ATOM   2289 C CA  . HIS B 2 62  ? 120.405 147.510 102.779 1.00 11.44  ? 62  HIS B CA  1 
ATOM   2290 C C   . HIS B 2 62  ? 120.482 148.803 103.572 1.00 11.44  ? 62  HIS B C   1 
ATOM   2291 O O   . HIS B 2 62  ? 119.895 148.927 104.647 1.00 11.44  ? 62  HIS B O   1 
ATOM   2292 C CB  . HIS B 2 62  ? 119.316 147.611 101.707 1.00 11.44  ? 62  HIS B CB  1 
ATOM   2293 C CG  . HIS B 2 62  ? 119.781 148.247 100.434 1.00 11.44  ? 62  HIS B CG  1 
ATOM   2294 N ND1 . HIS B 2 62  ? 118.915 148.827 99.534  1.00 11.44  ? 62  HIS B ND1 1 
ATOM   2295 C CD2 . HIS B 2 62  ? 121.020 148.390 99.908  1.00 11.44  ? 62  HIS B CD2 1 
ATOM   2296 C CE1 . HIS B 2 62  ? 119.601 149.305 98.511  1.00 11.44  ? 62  HIS B CE1 1 
ATOM   2297 N NE2 . HIS B 2 62  ? 120.881 149.052 98.713  1.00 11.44  ? 62  HIS B NE2 1 
ATOM   2298 N N   . TRP B 2 63  ? 121.222 149.760 103.029 1.00 10.89  ? 63  TRP B N   1 
ATOM   2299 C CA  . TRP B 2 63  ? 121.429 151.039 103.682 1.00 10.89  ? 63  TRP B CA  1 
ATOM   2300 C C   . TRP B 2 63  ? 120.329 152.018 103.280 1.00 10.89  ? 63  TRP B C   1 
ATOM   2301 O O   . TRP B 2 63  ? 119.396 151.687 102.547 1.00 10.89  ? 63  TRP B O   1 
ATOM   2302 C CB  . TRP B 2 63  ? 122.810 151.586 103.327 1.00 10.89  ? 63  TRP B CB  1 
ATOM   2303 C CG  . TRP B 2 63  ? 123.881 151.162 104.273 1.00 10.89  ? 63  TRP B CG  1 
ATOM   2304 C CD1 . TRP B 2 63  ? 124.872 150.262 104.035 1.00 10.89  ? 63  TRP B CD1 1 
ATOM   2305 C CD2 . TRP B 2 63  ? 124.073 151.626 105.611 1.00 10.89  ? 63  TRP B CD2 1 
ATOM   2306 N NE1 . TRP B 2 63  ? 125.669 150.133 105.142 1.00 10.89  ? 63  TRP B NE1 1 
ATOM   2307 C CE2 . TRP B 2 63  ? 125.198 150.961 106.125 1.00 10.89  ? 63  TRP B CE2 1 
ATOM   2308 C CE3 . TRP B 2 63  ? 123.401 152.540 106.424 1.00 10.89  ? 63  TRP B CE3 1 
ATOM   2309 C CZ2 . TRP B 2 63  ? 125.666 151.180 107.413 1.00 10.89  ? 63  TRP B CZ2 1 
ATOM   2310 C CZ3 . TRP B 2 63  ? 123.866 152.754 107.701 1.00 10.89  ? 63  TRP B CZ3 1 
ATOM   2311 C CH2 . TRP B 2 63  ? 124.988 152.078 108.184 1.00 10.89  ? 63  TRP B CH2 1 
ATOM   2312 N N   . GLY B 2 64  ? 120.436 153.242 103.781 1.00 12.32  ? 64  GLY B N   1 
ATOM   2313 C CA  . GLY B 2 64  ? 119.601 154.335 103.331 1.00 12.32  ? 64  GLY B CA  1 
ATOM   2314 C C   . GLY B 2 64  ? 120.468 155.393 102.680 1.00 12.32  ? 64  GLY B C   1 
ATOM   2315 O O   . GLY B 2 64  ? 121.656 155.514 102.982 1.00 12.32  ? 64  GLY B O   1 
ATOM   2316 N N   . THR B 2 65  ? 119.866 156.164 101.778 1.00 13.92  ? 65  THR B N   1 
ATOM   2317 C CA  . THR B 2 65  ? 120.635 157.171 101.058 1.00 13.92  ? 65  THR B CA  1 
ATOM   2318 C C   . THR B 2 65  ? 121.232 158.214 101.992 1.00 13.92  ? 65  THR B C   1 
ATOM   2319 O O   . THR B 2 65  ? 122.180 158.904 101.604 1.00 13.92  ? 65  THR B O   1 
ATOM   2320 C CB  . THR B 2 65  ? 119.760 157.853 100.009 1.00 13.92  ? 65  THR B CB  1 
ATOM   2321 O OG1 . THR B 2 65  ? 118.548 158.314 100.616 1.00 13.92  ? 65  THR B OG1 1 
ATOM   2322 C CG2 . THR B 2 65  ? 119.427 156.885 98.887  1.00 13.92  ? 65  THR B CG2 1 
ATOM   2323 N N   . ASP B 2 66  ? 120.708 158.345 103.209 1.00 16.53  ? 66  ASP B N   1 
ATOM   2324 C CA  . ASP B 2 66  ? 121.245 159.278 104.190 1.00 16.53  ? 66  ASP B CA  1 
ATOM   2325 C C   . ASP B 2 66  ? 122.313 158.655 105.079 1.00 16.53  ? 66  ASP B C   1 
ATOM   2326 O O   . ASP B 2 66  ? 122.844 159.341 105.957 1.00 16.53  ? 66  ASP B O   1 
ATOM   2327 C CB  . ASP B 2 66  ? 120.116 159.835 105.062 1.00 16.53  ? 66  ASP B CB  1 
ATOM   2328 C CG  . ASP B 2 66  ? 119.371 158.751 105.811 1.00 16.53  ? 66  ASP B CG  1 
ATOM   2329 O OD1 . ASP B 2 66  ? 119.313 157.610 105.307 1.00 16.53  ? 66  ASP B OD1 1 
ATOM   2330 O OD2 . ASP B 2 66  ? 118.840 159.038 106.904 1.00 16.53  ? 66  ASP B OD2 1 
ATOM   2331 N N   . SER B 2 67  ? 122.634 157.378 104.882 1.00 14.25  ? 67  SER B N   1 
ATOM   2332 C CA  . SER B 2 67  ? 123.712 156.708 105.607 1.00 14.25  ? 67  SER B CA  1 
ATOM   2333 C C   . SER B 2 67  ? 123.506 156.755 107.118 1.00 14.25  ? 67  SER B C   1 
ATOM   2334 O O   . SER B 2 67  ? 124.471 156.724 107.885 1.00 14.25  ? 67  SER B O   1 
ATOM   2335 C CB  . SER B 2 67  ? 125.071 157.308 105.245 1.00 14.25  ? 67  SER B CB  1 
ATOM   2336 O OG  . SER B 2 67  ? 125.364 157.098 103.877 1.00 14.25  ? 67  SER B OG  1 
ATOM   2337 N N   . ARG B 2 68  ? 122.254 156.836 107.561 1.00 14.59  ? 68  ARG B N   1 
ATOM   2338 C CA  . ARG B 2 68  ? 121.919 156.744 108.978 1.00 14.59  ? 68  ARG B CA  1 
ATOM   2339 C C   . ARG B 2 68  ? 121.037 155.546 109.282 1.00 14.59  ? 68  ARG B C   1 
ATOM   2340 O O   . ARG B 2 68  ? 121.369 154.746 110.163 1.00 14.59  ? 68  ARG B O   1 
ATOM   2341 C CB  . ARG B 2 68  ? 121.221 158.031 109.446 1.00 14.59  ? 68  ARG B CB  1 
ATOM   2342 C CG  . ARG B 2 68  ? 120.716 157.963 110.880 1.00 14.59  ? 68  ARG B CG  1 
ATOM   2343 C CD  . ARG B 2 68  ? 120.441 159.342 111.456 1.00 14.59  ? 68  ARG B CD  1 
ATOM   2344 N NE  . ARG B 2 68  ? 120.394 159.324 112.915 1.00 14.59  ? 68  ARG B NE  1 
ATOM   2345 C CZ  . ARG B 2 68  ? 120.525 160.396 113.686 1.00 14.59  ? 68  ARG B CZ  1 
ATOM   2346 N NH1 . ARG B 2 68  ? 120.705 161.601 113.173 1.00 14.59  ? 68  ARG B NH1 1 
ATOM   2347 N NH2 . ARG B 2 68  ? 120.475 160.253 115.006 1.00 14.59  ? 68  ARG B NH2 1 
ATOM   2348 N N   . LEU B 2 69  ? 119.922 155.400 108.576 1.00 12.60  ? 69  LEU B N   1 
ATOM   2349 C CA  . LEU B 2 69  ? 119.011 154.287 108.782 1.00 12.60  ? 69  LEU B CA  1 
ATOM   2350 C C   . LEU B 2 69  ? 119.364 153.138 107.851 1.00 12.60  ? 69  LEU B C   1 
ATOM   2351 O O   . LEU B 2 69  ? 119.892 153.342 106.756 1.00 12.60  ? 69  LEU B O   1 
ATOM   2352 C CB  . LEU B 2 69  ? 117.567 154.723 108.537 1.00 12.60  ? 69  LEU B CB  1 
ATOM   2353 C CG  . LEU B 2 69  ? 116.992 155.753 109.509 1.00 12.60  ? 69  LEU B CG  1 
ATOM   2354 C CD1 . LEU B 2 69  ? 115.800 156.459 108.894 1.00 12.60  ? 69  LEU B CD1 1 
ATOM   2355 C CD2 . LEU B 2 69  ? 116.595 155.089 110.810 1.00 12.60  ? 69  LEU B CD2 1 
ATOM   2356 N N   . LEU B 2 70  ? 119.070 151.921 108.299 1.00 12.61  ? 70  LEU B N   1 
ATOM   2357 C CA  . LEU B 2 70  ? 119.232 150.747 107.456 1.00 12.61  ? 70  LEU B CA  1 
ATOM   2358 C C   . LEU B 2 70  ? 118.152 149.738 107.811 1.00 12.61  ? 70  LEU B C   1 
ATOM   2359 O O   . LEU B 2 70  ? 117.547 149.796 108.883 1.00 12.61  ? 70  LEU B O   1 
ATOM   2360 C CB  . LEU B 2 70  ? 120.626 150.123 107.598 1.00 12.61  ? 70  LEU B CB  1 
ATOM   2361 C CG  . LEU B 2 70  ? 120.978 149.360 108.873 1.00 12.61  ? 70  LEU B CG  1 
ATOM   2362 C CD1 . LEU B 2 70  ? 122.215 148.523 108.639 1.00 12.61  ? 70  LEU B CD1 1 
ATOM   2363 C CD2 . LEU B 2 70  ? 121.200 150.309 110.028 1.00 12.61  ? 70  LEU B CD2 1 
ATOM   2364 N N   . VAL B 2 71  ? 117.918 148.812 106.890 1.00 10.38  ? 71  VAL B N   1 
ATOM   2365 C CA  . VAL B 2 71  ? 116.861 147.815 107.006 1.00 10.38  ? 71  VAL B CA  1 
ATOM   2366 C C   . VAL B 2 71  ? 117.491 146.439 106.877 1.00 10.38  ? 71  VAL B C   1 
ATOM   2367 O O   . VAL B 2 71  ? 118.331 146.217 106.000 1.00 10.38  ? 71  VAL B O   1 
ATOM   2368 C CB  . VAL B 2 71  ? 115.773 148.022 105.937 1.00 10.38  ? 71  VAL B CB  1 
ATOM   2369 C CG1 . VAL B 2 71  ? 116.360 147.880 104.549 1.00 10.38  ? 71  VAL B CG1 1 
ATOM   2370 C CG2 . VAL B 2 71  ? 114.647 147.038 106.137 1.00 10.38  ? 71  VAL B CG2 1 
ATOM   2371 N N   . SER B 2 72  ? 117.089 145.521 107.751 1.00 10.77  ? 72  SER B N   1 
ATOM   2372 C CA  . SER B 2 72  ? 117.608 144.162 107.757 1.00 10.77  ? 72  SER B CA  1 
ATOM   2373 C C   . SER B 2 72  ? 116.452 143.178 107.788 1.00 10.77  ? 72  SER B C   1 
ATOM   2374 O O   . SER B 2 72  ? 115.422 143.439 108.415 1.00 10.77  ? 72  SER B O   1 
ATOM   2375 C CB  . SER B 2 72  ? 118.517 143.923 108.957 1.00 10.77  ? 72  SER B CB  1 
ATOM   2376 O OG  . SER B 2 72  ? 117.753 143.568 110.094 1.00 10.77  ? 72  SER B OG  1 
ATOM   2377 N N   . ALA B 2 73  ? 116.630 142.044 107.116 1.00 9.93   ? 73  ALA B N   1 
ATOM   2378 C CA  . ALA B 2 73  ? 115.601 141.022 107.003 1.00 9.93   ? 73  ALA B CA  1 
ATOM   2379 C C   . ALA B 2 73  ? 116.126 139.699 107.534 1.00 9.93   ? 73  ALA B C   1 
ATOM   2380 O O   . ALA B 2 73  ? 117.276 139.330 107.286 1.00 9.93   ? 73  ALA B O   1 
ATOM   2381 C CB  . ALA B 2 73  ? 115.150 140.854 105.551 1.00 9.93   ? 73  ALA B CB  1 
ATOM   2382 N N   . SER B 2 74  ? 115.273 138.988 108.264 1.00 15.45  ? 74  SER B N   1 
ATOM   2383 C CA  . SER B 2 74  ? 115.592 137.683 108.818 1.00 15.45  ? 74  SER B CA  1 
ATOM   2384 C C   . SER B 2 74  ? 114.438 136.735 108.534 1.00 15.45  ? 74  SER B C   1 
ATOM   2385 O O   . SER B 2 74  ? 113.367 137.147 108.083 1.00 15.45  ? 74  SER B O   1 
ATOM   2386 C CB  . SER B 2 74  ? 115.856 137.769 110.323 1.00 15.45  ? 74  SER B CB  1 
ATOM   2387 O OG  . SER B 2 74  ? 115.838 136.482 110.911 1.00 15.45  ? 74  SER B OG  1 
ATOM   2388 N N   . GLN B 2 75  ? 114.655 135.447 108.801 1.00 16.32  ? 75  GLN B N   1 
ATOM   2389 C CA  . GLN B 2 75  ? 113.632 134.441 108.558 1.00 16.32  ? 75  GLN B CA  1 
ATOM   2390 C C   . GLN B 2 75  ? 112.840 134.087 109.808 1.00 16.32  ? 75  GLN B C   1 
ATOM   2391 O O   . GLN B 2 75  ? 112.317 132.971 109.903 1.00 16.32  ? 75  GLN B O   1 
ATOM   2392 C CB  . GLN B 2 75  ? 114.245 133.182 107.950 1.00 16.32  ? 75  GLN B CB  1 
ATOM   2393 C CG  . GLN B 2 75  ? 114.566 133.341 106.484 1.00 16.32  ? 75  GLN B CG  1 
ATOM   2394 C CD  . GLN B 2 75  ? 114.999 132.051 105.841 1.00 16.32  ? 75  GLN B CD  1 
ATOM   2395 O OE1 . GLN B 2 75  ? 115.675 131.232 106.459 1.00 16.32  ? 75  GLN B OE1 1 
ATOM   2396 N NE2 . GLN B 2 75  ? 114.644 131.876 104.577 1.00 16.32  ? 75  GLN B NE2 1 
ATOM   2397 N N   . ASP B 2 76  ? 112.743 135.002 110.764 1.00 17.81  ? 76  ASP B N   1 
ATOM   2398 C CA  . ASP B 2 76  ? 111.694 134.944 111.769 1.00 17.81  ? 76  ASP B CA  1 
ATOM   2399 C C   . ASP B 2 76  ? 110.475 135.751 111.351 1.00 17.81  ? 76  ASP B C   1 
ATOM   2400 O O   . ASP B 2 76  ? 109.506 135.830 112.112 1.00 17.81  ? 76  ASP B O   1 
ATOM   2401 C CB  . ASP B 2 76  ? 112.211 135.441 113.125 1.00 17.81  ? 76  ASP B CB  1 
ATOM   2402 C CG  . ASP B 2 76  ? 113.004 136.724 113.017 1.00 17.81  ? 76  ASP B CG  1 
ATOM   2403 O OD1 . ASP B 2 76  ? 113.828 136.835 112.089 1.00 17.81  ? 76  ASP B OD1 1 
ATOM   2404 O OD2 . ASP B 2 76  ? 112.807 137.622 113.863 1.00 17.81  ? 76  ASP B OD2 1 
ATOM   2405 N N   . GLY B 2 77  ? 110.503 136.343 110.158 1.00 16.71  ? 77  GLY B N   1 
ATOM   2406 C CA  . GLY B 2 77  ? 109.379 137.094 109.646 1.00 16.71  ? 77  GLY B CA  1 
ATOM   2407 C C   . GLY B 2 77  ? 109.391 138.568 109.967 1.00 16.71  ? 77  GLY B C   1 
ATOM   2408 O O   . GLY B 2 77  ? 108.324 139.189 109.968 1.00 16.71  ? 77  GLY B O   1 
ATOM   2409 N N   . LYS B 2 78  ? 110.556 139.153 110.233 1.00 14.43  ? 78  LYS B N   1 
ATOM   2410 C CA  . LYS B 2 78  ? 110.653 140.527 110.700 1.00 14.43  ? 78  LYS B CA  1 
ATOM   2411 C C   . LYS B 2 78  ? 111.508 141.362 109.761 1.00 14.43  ? 78  LYS B C   1 
ATOM   2412 O O   . LYS B 2 78  ? 112.567 140.920 109.308 1.00 14.43  ? 78  LYS B O   1 
ATOM   2413 C CB  . LYS B 2 78  ? 111.252 140.586 112.106 1.00 14.43  ? 78  LYS B CB  1 
ATOM   2414 C CG  . LYS B 2 78  ? 110.303 140.149 113.203 1.00 14.43  ? 78  LYS B CG  1 
ATOM   2415 C CD  . LYS B 2 78  ? 109.244 141.196 113.478 1.00 14.43  ? 78  LYS B CD  1 
ATOM   2416 C CE  . LYS B 2 78  ? 108.291 140.740 114.565 1.00 14.43  ? 78  LYS B CE  1 
ATOM   2417 N NZ  . LYS B 2 78  ? 107.629 139.452 114.223 1.00 14.43  ? 78  LYS B NZ  1 
ATOM   2418 N N   . LEU B 2 79  ? 111.035 142.570 109.477 1.00 12.09  ? 79  LEU B N   1 
ATOM   2419 C CA  . LEU B 2 79  ? 111.834 143.627 108.873 1.00 12.09  ? 79  LEU B CA  1 
ATOM   2420 C C   . LEU B 2 79  ? 112.021 144.707 109.927 1.00 12.09  ? 79  LEU B C   1 
ATOM   2421 O O   . LEU B 2 79  ? 111.038 145.227 110.463 1.00 12.09  ? 79  LEU B O   1 
ATOM   2422 C CB  . LEU B 2 79  ? 111.149 144.204 107.635 1.00 12.09  ? 79  LEU B CB  1 
ATOM   2423 C CG  . LEU B 2 79  ? 111.561 143.684 106.261 1.00 12.09  ? 79  LEU B CG  1 
ATOM   2424 C CD1 . LEU B 2 79  ? 110.582 144.186 105.222 1.00 12.09  ? 79  LEU B CD1 1 
ATOM   2425 C CD2 . LEU B 2 79  ? 112.963 144.124 105.911 1.00 12.09  ? 79  LEU B CD2 1 
ATOM   2426 N N   . ILE B 2 80  ? 113.271 145.042 110.225 1.00 11.10  ? 80  ILE B N   1 
ATOM   2427 C CA  . ILE B 2 80  ? 113.596 145.988 111.283 1.00 11.10  ? 80  ILE B CA  1 
ATOM   2428 C C   . ILE B 2 80  ? 114.412 147.119 110.680 1.00 11.10  ? 80  ILE B C   1 
ATOM   2429 O O   . ILE B 2 80  ? 115.360 146.873 109.927 1.00 11.10  ? 80  ILE B O   1 
ATOM   2430 C CB  . ILE B 2 80  ? 114.362 145.312 112.432 1.00 11.10  ? 80  ILE B CB  1 
ATOM   2431 C CG1 . ILE B 2 80  ? 113.441 144.345 113.175 1.00 11.10  ? 80  ILE B CG1 1 
ATOM   2432 C CG2 . ILE B 2 80  ? 114.906 146.356 113.388 1.00 11.10  ? 80  ILE B CG2 1 
ATOM   2433 C CD1 . ILE B 2 80  ? 114.155 143.445 114.150 1.00 11.10  ? 80  ILE B CD1 1 
ATOM   2434 N N   . ILE B 2 81  ? 114.044 148.351 111.011 1.00 12.59  ? 81  ILE B N   1 
ATOM   2435 C CA  . ILE B 2 81  ? 114.733 149.543 110.536 1.00 12.59  ? 81  ILE B CA  1 
ATOM   2436 C C   . ILE B 2 81  ? 115.477 150.136 111.724 1.00 12.59  ? 81  ILE B C   1 
ATOM   2437 O O   . ILE B 2 81  ? 114.856 150.616 112.679 1.00 12.59  ? 81  ILE B O   1 
ATOM   2438 C CB  . ILE B 2 81  ? 113.758 150.556 109.923 1.00 12.59  ? 81  ILE B CB  1 
ATOM   2439 C CG1 . ILE B 2 81  ? 112.786 149.837 108.988 1.00 12.59  ? 81  ILE B CG1 1 
ATOM   2440 C CG2 . ILE B 2 81  ? 114.516 151.636 109.177 1.00 12.59  ? 81  ILE B CG2 1 
ATOM   2441 C CD1 . ILE B 2 81  ? 111.907 150.759 108.185 1.00 12.59  ? 81  ILE B CD1 1 
ATOM   2442 N N   . TRP B 2 82  ? 116.804 150.109 111.666 1.00 12.55  ? 82  TRP B N   1 
ATOM   2443 C CA  . TRP B 2 82  ? 117.642 150.581 112.756 1.00 12.55  ? 82  TRP B CA  1 
ATOM   2444 C C   . TRP B 2 82  ? 118.139 151.990 112.480 1.00 12.55  ? 82  TRP B C   1 
ATOM   2445 O O   . TRP B 2 82  ? 118.403 152.364 111.336 1.00 12.55  ? 82  TRP B O   1 
ATOM   2446 C CB  . TRP B 2 82  ? 118.849 149.668 112.964 1.00 12.55  ? 82  TRP B CB  1 
ATOM   2447 C CG  . TRP B 2 82  ? 118.544 148.211 112.953 1.00 12.55  ? 82  TRP B CG  1 
ATOM   2448 C CD1 . TRP B 2 82  ? 118.293 147.433 111.865 1.00 12.55  ? 82  TRP B CD1 1 
ATOM   2449 C CD2 . TRP B 2 82  ? 118.478 147.345 114.090 1.00 12.55  ? 82  TRP B CD2 1 
ATOM   2450 N NE1 . TRP B 2 82  ? 118.066 146.138 112.252 1.00 12.55  ? 82  TRP B NE1 1 
ATOM   2451 C CE2 . TRP B 2 82  ? 118.175 146.058 113.614 1.00 12.55  ? 82  TRP B CE2 1 
ATOM   2452 C CE3 . TRP B 2 82  ? 118.642 147.536 115.462 1.00 12.55  ? 82  TRP B CE3 1 
ATOM   2453 C CZ2 . TRP B 2 82  ? 118.031 144.968 114.462 1.00 12.55  ? 82  TRP B CZ2 1 
ATOM   2454 C CZ3 . TRP B 2 82  ? 118.499 146.453 116.302 1.00 12.55  ? 82  TRP B CZ3 1 
ATOM   2455 C CH2 . TRP B 2 82  ? 118.198 145.185 115.799 1.00 12.55  ? 82  TRP B CH2 1 
ATOM   2456 N N   . ASP B 2 83  ? 118.267 152.769 113.547 1.00 14.34  ? 83  ASP B N   1 
ATOM   2457 C CA  . ASP B 2 83  ? 118.982 154.040 113.518 1.00 14.34  ? 83  ASP B CA  1 
ATOM   2458 C C   . ASP B 2 83  ? 120.390 153.746 114.020 1.00 14.34  ? 83  ASP B C   1 
ATOM   2459 O O   . ASP B 2 83  ? 120.626 153.669 115.227 1.00 14.34  ? 83  ASP B O   1 
ATOM   2460 C CB  . ASP B 2 83  ? 118.276 155.088 114.369 1.00 14.34  ? 83  ASP B CB  1 
ATOM   2461 C CG  . ASP B 2 83  ? 118.951 156.435 114.308 1.00 14.34  ? 83  ASP B CG  1 
ATOM   2462 O OD1 . ASP B 2 83  ? 119.963 156.562 113.592 1.00 14.34  ? 83  ASP B OD1 1 
ATOM   2463 O OD2 . ASP B 2 83  ? 118.469 157.372 114.973 1.00 14.34  ? 83  ASP B OD2 1 
ATOM   2464 N N   . SER B 2 84  ? 121.326 153.574 113.086 1.00 14.07  ? 84  SER B N   1 
ATOM   2465 C CA  . SER B 2 84  ? 122.628 153.019 113.441 1.00 14.07  ? 84  SER B CA  1 
ATOM   2466 C C   . SER B 2 84  ? 123.336 153.874 114.482 1.00 14.07  ? 84  SER B C   1 
ATOM   2467 O O   . SER B 2 84  ? 123.961 153.342 115.406 1.00 14.07  ? 84  SER B O   1 
ATOM   2468 C CB  . SER B 2 84  ? 123.493 152.875 112.190 1.00 14.07  ? 84  SER B CB  1 
ATOM   2469 O OG  . SER B 2 84  ? 123.910 154.140 111.716 1.00 14.07  ? 84  SER B OG  1 
ATOM   2470 N N   . TYR B 2 85  ? 123.256 155.198 114.353 1.00 16.45  ? 85  TYR B N   1 
ATOM   2471 C CA  . TYR B 2 85  ? 123.967 156.074 115.277 1.00 16.45  ? 85  TYR B CA  1 
ATOM   2472 C C   . TYR B 2 85  ? 123.596 155.770 116.723 1.00 16.45  ? 85  TYR B C   1 
ATOM   2473 O O   . TYR B 2 85  ? 124.470 155.553 117.568 1.00 16.45  ? 85  TYR B O   1 
ATOM   2474 C CB  . TYR B 2 85  ? 123.664 157.536 114.950 1.00 16.45  ? 85  TYR B CB  1 
ATOM   2475 C CG  . TYR B 2 85  ? 124.180 158.001 113.608 1.00 16.45  ? 85  TYR B CG  1 
ATOM   2476 C CD1 . TYR B 2 85  ? 125.196 157.320 112.955 1.00 16.45  ? 85  TYR B CD1 1 
ATOM   2477 C CD2 . TYR B 2 85  ? 123.653 159.127 112.998 1.00 16.45  ? 85  TYR B CD2 1 
ATOM   2478 C CE1 . TYR B 2 85  ? 125.668 157.744 111.734 1.00 16.45  ? 85  TYR B CE1 1 
ATOM   2479 C CE2 . TYR B 2 85  ? 124.117 159.559 111.776 1.00 16.45  ? 85  TYR B CE2 1 
ATOM   2480 C CZ  . TYR B 2 85  ? 125.127 158.863 111.148 1.00 16.45  ? 85  TYR B CZ  1 
ATOM   2481 O OH  . TYR B 2 85  ? 125.600 159.286 109.927 1.00 16.45  ? 85  TYR B OH  1 
ATOM   2482 N N   . THR B 2 86  ? 122.300 155.745 117.024 1.00 14.90  ? 86  THR B N   1 
ATOM   2483 C CA  . THR B 2 86  ? 121.820 155.527 118.380 1.00 14.90  ? 86  THR B CA  1 
ATOM   2484 C C   . THR B 2 86  ? 121.343 154.101 118.624 1.00 14.90  ? 86  THR B C   1 
ATOM   2485 O O   . THR B 2 86  ? 120.935 153.783 119.744 1.00 14.90  ? 86  THR B O   1 
ATOM   2486 C CB  . THR B 2 86  ? 120.688 156.506 118.696 1.00 14.90  ? 86  THR B CB  1 
ATOM   2487 O OG1 . THR B 2 86  ? 119.557 156.220 117.866 1.00 14.90  ? 86  THR B OG1 1 
ATOM   2488 C CG2 . THR B 2 86  ? 121.138 157.934 118.449 1.00 14.90  ? 86  THR B CG2 1 
ATOM   2489 N N   . THR B 2 87  ? 121.381 153.239 117.613 1.00 14.10  ? 87  THR B N   1 
ATOM   2490 C CA  . THR B 2 87  ? 121.033 151.826 117.730 1.00 14.10  ? 87  THR B CA  1 
ATOM   2491 C C   . THR B 2 87  ? 119.571 151.598 118.087 1.00 14.10  ? 87  THR B C   1 
ATOM   2492 O O   . THR B 2 87  ? 119.195 150.476 118.443 1.00 14.10  ? 87  THR B O   1 
ATOM   2493 C CB  . THR B 2 87  ? 121.917 151.117 118.761 1.00 14.10  ? 87  THR B CB  1 
ATOM   2494 O OG1 . THR B 2 87  ? 121.450 151.417 120.081 1.00 14.10  ? 87  THR B OG1 1 
ATOM   2495 C CG2 . THR B 2 87  ? 123.359 151.563 118.621 1.00 14.10  ? 87  THR B CG2 1 
ATOM   2496 N N   . ASN B 2 88  ? 118.731 152.625 118.005 1.00 16.07  ? 88  ASN B N   1 
ATOM   2497 C CA  . ASN B 2 88  ? 117.317 152.441 118.282 1.00 16.07  ? 88  ASN B CA  1 
ATOM   2498 C C   . ASN B 2 88  ? 116.642 151.704 117.129 1.00 16.07  ? 88  ASN B C   1 
ATOM   2499 O O   . ASN B 2 88  ? 117.181 151.594 116.026 1.00 16.07  ? 88  ASN B O   1 
ATOM   2500 C CB  . ASN B 2 88  ? 116.634 153.789 118.504 1.00 16.07  ? 88  ASN B CB  1 
ATOM   2501 C CG  . ASN B 2 88  ? 117.339 154.633 119.541 1.00 16.07  ? 88  ASN B CG  1 
ATOM   2502 O OD1 . ASN B 2 88  ? 117.683 155.787 119.287 1.00 16.07  ? 88  ASN B OD1 1 
ATOM   2503 N ND2 . ASN B 2 88  ? 117.559 154.064 120.718 1.00 16.07  ? 88  ASN B ND2 1 
ATOM   2504 N N   . LYS B 2 89  ? 115.447 151.190 117.400 1.00 14.41  ? 89  LYS B N   1 
ATOM   2505 C CA  . LYS B 2 89  ? 114.609 150.572 116.382 1.00 14.41  ? 89  LYS B CA  1 
ATOM   2506 C C   . LYS B 2 89  ? 113.510 151.553 115.997 1.00 14.41  ? 89  LYS B C   1 
ATOM   2507 O O   . LYS B 2 89  ? 112.692 151.935 116.839 1.00 14.41  ? 89  LYS B O   1 
ATOM   2508 C CB  . LYS B 2 89  ? 113.996 149.267 116.884 1.00 14.41  ? 89  LYS B CB  1 
ATOM   2509 C CG  . LYS B 2 89  ? 114.997 148.213 117.299 1.00 14.41  ? 89  LYS B CG  1 
ATOM   2510 C CD  . LYS B 2 89  ? 114.285 146.950 117.744 1.00 14.41  ? 89  LYS B CD  1 
ATOM   2511 C CE  . LYS B 2 89  ? 115.236 145.975 118.403 1.00 14.41  ? 89  LYS B CE  1 
ATOM   2512 N NZ  . LYS B 2 89  ? 115.636 146.419 119.762 1.00 14.41  ? 89  LYS B NZ  1 
ATOM   2513 N N   . VAL B 2 90  ? 113.489 151.952 114.728 1.00 13.61  ? 90  VAL B N   1 
ATOM   2514 C CA  . VAL B 2 90  ? 112.477 152.896 114.271 1.00 13.61  ? 90  VAL B CA  1 
ATOM   2515 C C   . VAL B 2 90  ? 111.186 152.171 113.923 1.00 13.61  ? 90  VAL B C   1 
ATOM   2516 O O   . VAL B 2 90  ? 110.098 152.573 114.349 1.00 13.61  ? 90  VAL B O   1 
ATOM   2517 C CB  . VAL B 2 90  ? 113.006 153.707 113.075 1.00 13.61  ? 90  VAL B CB  1 
ATOM   2518 C CG1 . VAL B 2 90  ? 112.110 154.901 112.813 1.00 13.61  ? 90  VAL B CG1 1 
ATOM   2519 C CG2 . VAL B 2 90  ? 114.430 154.154 113.331 1.00 13.61  ? 90  VAL B CG2 1 
ATOM   2520 N N   . HIS B 2 91  ? 111.285 151.095 113.149 1.00 13.58  ? 91  HIS B N   1 
ATOM   2521 C CA  . HIS B 2 91  ? 110.128 150.320 112.734 1.00 13.58  ? 91  HIS B CA  1 
ATOM   2522 C C   . HIS B 2 91  ? 110.395 148.840 112.959 1.00 13.58  ? 91  HIS B C   1 
ATOM   2523 O O   . HIS B 2 91  ? 111.535 148.413 113.148 1.00 13.58  ? 91  HIS B O   1 
ATOM   2524 C CB  . HIS B 2 91  ? 109.785 150.557 111.257 1.00 13.58  ? 91  HIS B CB  1 
ATOM   2525 C CG  . HIS B 2 91  ? 109.274 151.933 110.965 1.00 13.58  ? 91  HIS B CG  1 
ATOM   2526 N ND1 . HIS B 2 91  ? 110.059 152.912 110.395 1.00 13.58  ? 91  HIS B ND1 1 
ATOM   2527 C CD2 . HIS B 2 91  ? 108.056 152.490 111.153 1.00 13.58  ? 91  HIS B CD2 1 
ATOM   2528 C CE1 . HIS B 2 91  ? 109.347 154.014 110.250 1.00 13.58  ? 91  HIS B CE1 1 
ATOM   2529 N NE2 . HIS B 2 91  ? 108.128 153.785 110.703 1.00 13.58  ? 91  HIS B NE2 1 
ATOM   2530 N N   . ALA B 2 92  ? 109.319 148.062 112.939 1.00 14.03  ? 92  ALA B N   1 
ATOM   2531 C CA  . ALA B 2 92  ? 109.411 146.607 112.974 1.00 14.03  ? 92  ALA B CA  1 
ATOM   2532 C C   . ALA B 2 92  ? 108.186 146.061 112.263 1.00 14.03  ? 92  ALA B C   1 
ATOM   2533 O O   . ALA B 2 92  ? 107.061 146.258 112.732 1.00 14.03  ? 92  ALA B O   1 
ATOM   2534 C CB  . ALA B 2 92  ? 109.492 146.086 114.406 1.00 14.03  ? 92  ALA B CB  1 
ATOM   2535 N N   . ILE B 2 93  ? 108.399 145.391 111.140 1.00 12.18  ? 93  ILE B N   1 
ATOM   2536 C CA  . ILE B 2 93  ? 107.328 144.981 110.238 1.00 12.18  ? 93  ILE B CA  1 
ATOM   2537 C C   . ILE B 2 93  ? 107.192 143.463 110.321 1.00 12.18  ? 93  ILE B C   1 
ATOM   2538 O O   . ILE B 2 93  ? 108.146 142.747 109.995 1.00 12.18  ? 93  ILE B O   1 
ATOM   2539 C CB  . ILE B 2 93  ? 107.611 145.426 108.795 1.00 12.18  ? 93  ILE B CB  1 
ATOM   2540 C CG1 . ILE B 2 93  ? 107.704 146.949 108.725 1.00 12.18  ? 93  ILE B CG1 1 
ATOM   2541 C CG2 . ILE B 2 93  ? 106.523 144.924 107.869 1.00 12.18  ? 93  ILE B CG2 1 
ATOM   2542 C CD1 . ILE B 2 93  ? 108.248 147.472 107.421 1.00 12.18  ? 93  ILE B CD1 1 
ATOM   2543 N N   . PRO B 2 94  ? 106.046 142.928 110.750 1.00 15.39  ? 94  PRO B N   1 
ATOM   2544 C CA  . PRO B 2 94  ? 105.852 141.470 110.723 1.00 15.39  ? 94  PRO B CA  1 
ATOM   2545 C C   . PRO B 2 94  ? 105.440 141.010 109.332 1.00 15.39  ? 94  PRO B C   1 
ATOM   2546 O O   . PRO B 2 94  ? 104.358 141.350 108.848 1.00 15.39  ? 94  PRO B O   1 
ATOM   2547 C CB  . PRO B 2 94  ? 104.734 141.246 111.745 1.00 15.39  ? 94  PRO B CB  1 
ATOM   2548 C CG  . PRO B 2 94  ? 103.947 142.501 111.704 1.00 15.39  ? 94  PRO B CG  1 
ATOM   2549 C CD  . PRO B 2 94  ? 104.905 143.618 111.378 1.00 15.39  ? 94  PRO B CD  1 
ATOM   2550 N N   . LEU B 2 95  ? 106.304 140.229 108.690 1.00 13.42  ? 95  LEU B N   1 
ATOM   2551 C CA  . LEU B 2 95  ? 106.057 139.791 107.326 1.00 13.42  ? 95  LEU B CA  1 
ATOM   2552 C C   . LEU B 2 95  ? 104.986 138.705 107.287 1.00 13.42  ? 95  LEU B C   1 
ATOM   2553 O O   . LEU B 2 95  ? 104.749 137.987 108.260 1.00 13.42  ? 95  LEU B O   1 
ATOM   2554 C CB  . LEU B 2 95  ? 107.343 139.266 106.693 1.00 13.42  ? 95  LEU B CB  1 
ATOM   2555 C CG  . LEU B 2 95  ? 108.452 140.291 106.471 1.00 13.42  ? 95  LEU B CG  1 
ATOM   2556 C CD1 . LEU B 2 95  ? 109.695 139.612 105.936 1.00 13.42  ? 95  LEU B CD1 1 
ATOM   2557 C CD2 . LEU B 2 95  ? 107.989 141.376 105.525 1.00 13.42  ? 95  LEU B CD2 1 
ATOM   2558 N N   . ARG B 2 96  ? 104.335 138.593 106.127 1.00 14.99  ? 96  ARG B N   1 
ATOM   2559 C CA  . ARG B 2 96  ? 103.331 137.551 105.938 1.00 14.99  ? 96  ARG B CA  1 
ATOM   2560 C C   . ARG B 2 96  ? 103.977 136.179 105.804 1.00 14.99  ? 96  ARG B C   1 
ATOM   2561 O O   . ARG B 2 96  ? 103.509 135.205 106.406 1.00 14.99  ? 96  ARG B O   1 
ATOM   2562 C CB  . ARG B 2 96  ? 102.484 137.862 104.708 1.00 14.99  ? 96  ARG B CB  1 
ATOM   2563 C CG  . ARG B 2 96  ? 101.178 137.096 104.651 1.00 14.99  ? 96  ARG B CG  1 
ATOM   2564 C CD  . ARG B 2 96  ? 99.996  137.970 105.040 1.00 14.99  ? 96  ARG B CD  1 
ATOM   2565 N NE  . ARG B 2 96  ? 99.868  139.138 104.178 1.00 14.99  ? 96  ARG B NE  1 
ATOM   2566 C CZ  . ARG B 2 96  ? 99.526  139.095 102.898 1.00 14.99  ? 96  ARG B CZ  1 
ATOM   2567 N NH1 . ARG B 2 96  ? 99.254  137.950 102.291 1.00 14.99  ? 96  ARG B NH1 1 
ATOM   2568 N NH2 . ARG B 2 96  ? 99.453  140.229 102.207 1.00 14.99  ? 96  ARG B NH2 1 
ATOM   2569 N N   . SER B 2 97  ? 105.045 136.080 105.019 1.00 15.64  ? 97  SER B N   1 
ATOM   2570 C CA  . SER B 2 97  ? 105.788 134.841 104.831 1.00 15.64  ? 97  SER B CA  1 
ATOM   2571 C C   . SER B 2 97  ? 107.171 134.997 105.442 1.00 15.64  ? 97  SER B C   1 
ATOM   2572 O O   . SER B 2 97  ? 107.866 135.982 105.172 1.00 15.64  ? 97  SER B O   1 
ATOM   2573 C CB  . SER B 2 97  ? 105.900 134.488 103.349 1.00 15.64  ? 97  SER B CB  1 
ATOM   2574 O OG  . SER B 2 97  ? 106.789 133.405 103.153 1.00 15.64  ? 97  SER B OG  1 
ATOM   2575 N N   . SER B 2 98  ? 107.571 134.025 106.255 1.00 16.53  ? 98  SER B N   1 
ATOM   2576 C CA  . SER B 2 98  ? 108.802 134.128 107.025 1.00 16.53  ? 98  SER B CA  1 
ATOM   2577 C C   . SER B 2 98  ? 110.045 133.739 106.237 1.00 16.53  ? 98  SER B C   1 
ATOM   2578 O O   . SER B 2 98  ? 111.150 133.855 106.772 1.00 16.53  ? 98  SER B O   1 
ATOM   2579 C CB  . SER B 2 98  ? 108.702 133.258 108.278 1.00 16.53  ? 98  SER B CB  1 
ATOM   2580 O OG  . SER B 2 98  ? 108.380 131.921 107.944 1.00 16.53  ? 98  SER B OG  1 
ATOM   2581 N N   . TRP B 2 99  ? 109.902 133.281 104.994 1.00 15.31  ? 99  TRP B N   1 
ATOM   2582 C CA  . TRP B 2 99  ? 111.050 132.852 104.195 1.00 15.31  ? 99  TRP B CA  1 
ATOM   2583 C C   . TRP B 2 99  ? 111.449 133.972 103.234 1.00 15.31  ? 99  TRP B C   1 
ATOM   2584 O O   . TRP B 2 99  ? 111.126 133.972 102.047 1.00 15.31  ? 99  TRP B O   1 
ATOM   2585 C CB  . TRP B 2 99  ? 110.723 131.563 103.455 1.00 15.31  ? 99  TRP B CB  1 
ATOM   2586 C CG  . TRP B 2 99  ? 110.285 130.471 104.372 1.00 15.31  ? 99  TRP B CG  1 
ATOM   2587 C CD1 . TRP B 2 99  ? 109.037 129.938 104.473 1.00 15.31  ? 99  TRP B CD1 1 
ATOM   2588 C CD2 . TRP B 2 99  ? 111.093 129.788 105.332 1.00 15.31  ? 99  TRP B CD2 1 
ATOM   2589 N NE1 . TRP B 2 99  ? 109.017 128.961 105.436 1.00 15.31  ? 99  TRP B NE1 1 
ATOM   2590 C CE2 . TRP B 2 99  ? 110.270 128.850 105.978 1.00 15.31  ? 99  TRP B CE2 1 
ATOM   2591 C CE3 . TRP B 2 99  ? 112.434 129.876 105.709 1.00 15.31  ? 99  TRP B CE3 1 
ATOM   2592 C CZ2 . TRP B 2 99  ? 110.745 128.009 106.976 1.00 15.31  ? 99  TRP B CZ2 1 
ATOM   2593 C CZ3 . TRP B 2 99  ? 112.901 129.039 106.699 1.00 15.31  ? 99  TRP B CZ3 1 
ATOM   2594 C CH2 . TRP B 2 99  ? 112.061 128.119 107.321 1.00 15.31  ? 99  TRP B CH2 1 
ATOM   2595 N N   . VAL B 2 100 ? 112.176 134.942 103.782 1.00 14.68  ? 100 VAL B N   1 
ATOM   2596 C CA  . VAL B 2 100 ? 112.571 136.147 103.059 1.00 14.68  ? 100 VAL B CA  1 
ATOM   2597 C C   . VAL B 2 100 ? 114.061 136.073 102.761 1.00 14.68  ? 100 VAL B C   1 
ATOM   2598 O O   . VAL B 2 100 ? 114.868 135.784 103.653 1.00 14.68  ? 100 VAL B O   1 
ATOM   2599 C CB  . VAL B 2 100 ? 112.232 137.414 103.862 1.00 14.68  ? 100 VAL B CB  1 
ATOM   2600 C CG1 . VAL B 2 100 ? 113.059 137.479 105.135 1.00 14.68  ? 100 VAL B CG1 1 
ATOM   2601 C CG2 . VAL B 2 100 ? 112.440 138.655 103.010 1.00 14.68  ? 100 VAL B CG2 1 
ATOM   2602 N N   . MET B 2 101 ? 114.429 136.341 101.507 1.00 14.03  ? 101 MET B N   1 
ATOM   2603 C CA  . MET B 2 101 ? 115.807 136.224 101.056 1.00 14.03  ? 101 MET B CA  1 
ATOM   2604 C C   . MET B 2 101 ? 116.406 137.530 100.557 1.00 14.03  ? 101 MET B C   1 
ATOM   2605 O O   . MET B 2 101 ? 117.515 137.508 100.014 1.00 14.03  ? 101 MET B O   1 
ATOM   2606 C CB  . MET B 2 101 ? 115.909 135.179 99.939  1.00 14.03  ? 101 MET B CB  1 
ATOM   2607 C CG  . MET B 2 101 ? 115.474 133.786 100.347 1.00 14.03  ? 101 MET B CG  1 
ATOM   2608 S SD  . MET B 2 101 ? 115.281 132.683 98.937  1.00 14.03  ? 101 MET B SD  1 
ATOM   2609 C CE  . MET B 2 101 ? 116.978 132.531 98.393  1.00 14.03  ? 101 MET B CE  1 
ATOM   2610 N N   . THR B 2 102 ? 115.719 138.658 100.708 1.00 11.58  ? 102 THR B N   1 
ATOM   2611 C CA  . THR B 2 102 ? 116.265 139.922 100.230 1.00 11.58  ? 102 THR B CA  1 
ATOM   2612 C C   . THR B 2 102 ? 115.434 141.071 100.780 1.00 11.58  ? 102 THR B C   1 
ATOM   2613 O O   . THR B 2 102 ? 114.291 140.888 101.204 1.00 11.58  ? 102 THR B O   1 
ATOM   2614 C CB  . THR B 2 102 ? 116.297 139.979 98.702  1.00 11.58  ? 102 THR B CB  1 
ATOM   2615 O OG1 . THR B 2 102 ? 117.005 141.150 98.283  1.00 11.58  ? 102 THR B OG1 1 
ATOM   2616 C CG2 . THR B 2 102 ? 114.889 140.012 98.136  1.00 11.58  ? 102 THR B CG2 1 
ATOM   2617 N N   . CYS B 2 103 ? 116.032 142.261 100.758 1.00 7.72   ? 103 CYS B N   1 
ATOM   2618 C CA  . CYS B 2 103 ? 115.369 143.475 101.204 1.00 7.72   ? 103 CYS B CA  1 
ATOM   2619 C C   . CYS B 2 103 ? 116.011 144.664 100.507 1.00 7.72   ? 103 CYS B C   1 
ATOM   2620 O O   . CYS B 2 103 ? 117.201 144.640 100.182 1.00 7.72   ? 103 CYS B O   1 
ATOM   2621 C CB  . CYS B 2 103 ? 115.456 143.643 102.724 1.00 7.72   ? 103 CYS B CB  1 
ATOM   2622 S SG  . CYS B 2 103 ? 117.137 143.684 103.364 1.00 7.72   ? 103 CYS B SG  1 
ATOM   2623 N N   . ALA B 2 104 ? 115.213 145.703 100.277 1.00 10.37  ? 104 ALA B N   1 
ATOM   2624 C CA  . ALA B 2 104 ? 115.689 146.908 99.618  1.00 10.37  ? 104 ALA B CA  1 
ATOM   2625 C C   . ALA B 2 104 ? 115.096 148.132 100.297 1.00 10.37  ? 104 ALA B C   1 
ATOM   2626 O O   . ALA B 2 104 ? 113.985 148.092 100.828 1.00 10.37  ? 104 ALA B O   1 
ATOM   2627 C CB  . ALA B 2 104 ? 115.329 146.915 98.130  1.00 10.37  ? 104 ALA B CB  1 
ATOM   2628 N N   . TYR B 2 105 ? 115.857 149.223 100.272 1.00 11.86  ? 105 TYR B N   1 
ATOM   2629 C CA  . TYR B 2 105 ? 115.449 150.504 100.833 1.00 11.86  ? 105 TYR B CA  1 
ATOM   2630 C C   . TYR B 2 105 ? 115.329 151.501 99.691  1.00 11.86  ? 105 TYR B C   1 
ATOM   2631 O O   . TYR B 2 105 ? 116.286 151.696 98.935  1.00 11.86  ? 105 TYR B O   1 
ATOM   2632 C CB  . TYR B 2 105 ? 116.462 150.990 101.871 1.00 11.86  ? 105 TYR B CB  1 
ATOM   2633 C CG  . TYR B 2 105 ? 115.860 151.806 102.989 1.00 11.86  ? 105 TYR B CG  1 
ATOM   2634 C CD1 . TYR B 2 105 ? 115.372 151.196 104.132 1.00 11.86  ? 105 TYR B CD1 1 
ATOM   2635 C CD2 . TYR B 2 105 ? 115.775 153.184 102.900 1.00 11.86  ? 105 TYR B CD2 1 
ATOM   2636 C CE1 . TYR B 2 105 ? 114.822 151.935 105.154 1.00 11.86  ? 105 TYR B CE1 1 
ATOM   2637 C CE2 . TYR B 2 105 ? 115.226 153.929 103.917 1.00 11.86  ? 105 TYR B CE2 1 
ATOM   2638 C CZ  . TYR B 2 105 ? 114.751 153.301 105.041 1.00 11.86  ? 105 TYR B CZ  1 
ATOM   2639 O OH  . TYR B 2 105 ? 114.202 154.044 106.058 1.00 11.86  ? 105 TYR B OH  1 
ATOM   2640 N N   . ALA B 2 106 ? 114.166 152.132 99.570  1.00 12.57  ? 106 ALA B N   1 
ATOM   2641 C CA  . ALA B 2 106 ? 113.938 153.033 98.454  1.00 12.57  ? 106 ALA B CA  1 
ATOM   2642 C C   . ALA B 2 106 ? 114.898 154.220 98.532  1.00 12.57  ? 106 ALA B C   1 
ATOM   2643 O O   . ALA B 2 106 ? 115.254 154.666 99.626  1.00 12.57  ? 106 ALA B O   1 
ATOM   2644 C CB  . ALA B 2 106 ? 112.495 153.529 98.455  1.00 12.57  ? 106 ALA B CB  1 
ATOM   2645 N N   . PRO B 2 107 ? 115.338 154.749 97.387  1.00 12.86  ? 107 PRO B N   1 
ATOM   2646 C CA  . PRO B 2 107 ? 116.228 155.922 97.437  1.00 12.86  ? 107 PRO B CA  1 
ATOM   2647 C C   . PRO B 2 107 ? 115.615 157.110 98.155  1.00 12.86  ? 107 PRO B C   1 
ATOM   2648 O O   . PRO B 2 107 ? 116.329 157.854 98.838  1.00 12.86  ? 107 PRO B O   1 
ATOM   2649 C CB  . PRO B 2 107 ? 116.490 156.226 95.956  1.00 12.86  ? 107 PRO B CB  1 
ATOM   2650 C CG  . PRO B 2 107 ? 116.204 154.962 95.244  1.00 12.86  ? 107 PRO B CG  1 
ATOM   2651 C CD  . PRO B 2 107 ? 115.113 154.292 96.008  1.00 12.86  ? 107 PRO B CD  1 
ATOM   2652 N N   . SER B 2 108 ? 114.305 157.313 98.018  1.00 11.64  ? 108 SER B N   1 
ATOM   2653 C CA  . SER B 2 108 ? 113.628 158.415 98.688  1.00 11.64  ? 108 SER B CA  1 
ATOM   2654 C C   . SER B 2 108 ? 113.261 158.096 100.130 1.00 11.64  ? 108 SER B C   1 
ATOM   2655 O O   . SER B 2 108 ? 112.847 159.001 100.858 1.00 11.64  ? 108 SER B O   1 
ATOM   2656 C CB  . SER B 2 108 ? 112.366 158.797 97.916  1.00 11.64  ? 108 SER B CB  1 
ATOM   2657 O OG  . SER B 2 108 ? 111.456 157.713 97.862  1.00 11.64  ? 108 SER B OG  1 
ATOM   2658 N N   . GLY B 2 109 ? 113.397 156.844 100.556 1.00 13.57  ? 109 GLY B N   1 
ATOM   2659 C CA  . GLY B 2 109 ? 113.135 156.469 101.928 1.00 13.57  ? 109 GLY B CA  1 
ATOM   2660 C C   . GLY B 2 109 ? 111.682 156.217 102.265 1.00 13.57  ? 109 GLY B C   1 
ATOM   2661 O O   . GLY B 2 109 ? 111.382 155.891 103.419 1.00 13.57  ? 109 GLY B O   1 
ATOM   2662 N N   . ASN B 2 110 ? 110.771 156.357 101.303 1.00 15.25  ? 110 ASN B N   1 
ATOM   2663 C CA  . ASN B 2 110 ? 109.353 156.187 101.598 1.00 15.25  ? 110 ASN B CA  1 
ATOM   2664 C C   . ASN B 2 110 ? 108.967 154.719 101.726 1.00 15.25  ? 110 ASN B C   1 
ATOM   2665 O O   . ASN B 2 110 ? 108.107 154.376 102.543 1.00 15.25  ? 110 ASN B O   1 
ATOM   2666 C CB  . ASN B 2 110 ? 108.509 156.856 100.515 1.00 15.25  ? 110 ASN B CB  1 
ATOM   2667 C CG  . ASN B 2 110 ? 108.482 158.362 100.644 1.00 15.25  ? 110 ASN B CG  1 
ATOM   2668 O OD1 . ASN B 2 110 ? 108.563 158.902 101.744 1.00 15.25  ? 110 ASN B OD1 1 
ATOM   2669 N ND2 . ASN B 2 110 ? 108.366 159.050 99.516  1.00 15.25  ? 110 ASN B ND2 1 
ATOM   2670 N N   . TYR B 2 111 ? 109.580 153.842 100.935 1.00 15.34  ? 111 TYR B N   1 
ATOM   2671 C CA  . TYR B 2 111 ? 109.144 152.457 100.836 1.00 15.34  ? 111 TYR B CA  1 
ATOM   2672 C C   . TYR B 2 111 ? 110.306 151.505 101.074 1.00 15.34  ? 111 TYR B C   1 
ATOM   2673 O O   . TYR B 2 111 ? 111.475 151.855 100.904 1.00 15.34  ? 111 TYR B O   1 
ATOM   2674 C CB  . TYR B 2 111 ? 108.532 152.154 99.462  1.00 15.34  ? 111 TYR B CB  1 
ATOM   2675 C CG  . TYR B 2 111 ? 107.464 153.123 99.024  1.00 15.34  ? 111 TYR B CG  1 
ATOM   2676 C CD1 . TYR B 2 111 ? 106.260 153.210 99.701  1.00 15.34  ? 111 TYR B CD1 1 
ATOM   2677 C CD2 . TYR B 2 111 ? 107.658 153.944 97.926  1.00 15.34  ? 111 TYR B CD2 1 
ATOM   2678 C CE1 . TYR B 2 111 ? 105.283 154.091 99.301  1.00 15.34  ? 111 TYR B CE1 1 
ATOM   2679 C CE2 . TYR B 2 111 ? 106.687 154.827 97.521  1.00 15.34  ? 111 TYR B CE2 1 
ATOM   2680 C CZ  . TYR B 2 111 ? 105.501 154.897 98.211  1.00 15.34  ? 111 TYR B CZ  1 
ATOM   2681 O OH  . TYR B 2 111 ? 104.526 155.780 97.808  1.00 15.34  ? 111 TYR B OH  1 
ATOM   2682 N N   . VAL B 2 112 ? 109.952 150.282 101.473 1.00 13.24  ? 112 VAL B N   1 
ATOM   2683 C CA  . VAL B 2 112 ? 110.869 149.154 101.512 1.00 13.24  ? 112 VAL B CA  1 
ATOM   2684 C C   . VAL B 2 112 ? 110.191 147.983 100.816 1.00 13.24  ? 112 VAL B C   1 
ATOM   2685 O O   . VAL B 2 112 ? 108.963 147.900 100.745 1.00 13.24  ? 112 VAL B O   1 
ATOM   2686 C CB  . VAL B 2 112 ? 111.276 148.763 102.949 1.00 13.24  ? 112 VAL B CB  1 
ATOM   2687 C CG1 . VAL B 2 112 ? 112.045 149.886 103.608 1.00 13.24  ? 112 VAL B CG1 1 
ATOM   2688 C CG2 . VAL B 2 112 ? 110.054 148.399 103.771 1.00 13.24  ? 112 VAL B CG2 1 
ATOM   2689 N N   . ALA B 2 113 ? 111.010 147.068 100.301 1.00 28.35  ? 113 ALA B N   1 
ATOM   2690 C CA  . ALA B 2 113 ? 110.511 145.900 99.593  1.00 28.35  ? 113 ALA B CA  1 
ATOM   2691 C C   . ALA B 2 113 ? 111.285 144.670 100.039 1.00 28.35  ? 113 ALA B C   1 
ATOM   2692 O O   . ALA B 2 113 ? 112.454 144.759 100.421 1.00 28.35  ? 113 ALA B O   1 
ATOM   2693 C CB  . ALA B 2 113 ? 110.630 146.070 98.077  1.00 28.35  ? 113 ALA B CB  1 
ATOM   2694 N N   . CYS B 2 114 ? 110.622 143.518 99.984  1.00 12.01  ? 114 CYS B N   1 
ATOM   2695 C CA  . CYS B 2 114 ? 111.242 142.265 100.387 1.00 12.01  ? 114 CYS B CA  1 
ATOM   2696 C C   . CYS B 2 114 ? 110.537 141.113 99.689  1.00 12.01  ? 114 CYS B C   1 
ATOM   2697 O O   . CYS B 2 114 ? 109.332 141.171 99.431  1.00 12.01  ? 114 CYS B O   1 
ATOM   2698 C CB  . CYS B 2 114 ? 111.186 142.080 101.905 1.00 12.01  ? 114 CYS B CB  1 
ATOM   2699 S SG  . CYS B 2 114 ? 109.523 141.826 102.545 1.00 12.01  ? 114 CYS B SG  1 
ATOM   2700 N N   . GLY B 2 115 ? 111.302 140.062 99.396  1.00 14.14  ? 115 GLY B N   1 
ATOM   2701 C CA  . GLY B 2 115 ? 110.758 138.882 98.755  1.00 14.14  ? 115 GLY B CA  1 
ATOM   2702 C C   . GLY B 2 115 ? 111.580 137.661 99.104  1.00 14.14  ? 115 GLY B C   1 
ATOM   2703 O O   . GLY B 2 115 ? 112.652 137.756 99.703  1.00 14.14  ? 115 GLY B O   1 
ATOM   2704 N N   . GLY B 2 116 ? 111.061 136.500 98.716  1.00 14.16  ? 116 GLY B N   1 
ATOM   2705 C CA  . GLY B 2 116 ? 111.731 135.252 99.016  1.00 14.16  ? 116 GLY B CA  1 
ATOM   2706 C C   . GLY B 2 116 ? 111.113 134.051 98.333  1.00 14.16  ? 116 GLY B C   1 
ATOM   2707 O O   . GLY B 2 116 ? 110.748 134.115 97.157  1.00 14.16  ? 116 GLY B O   1 
ATOM   2708 N N   . LEU B 2 117 ? 110.991 132.943 99.067  1.00 13.60  ? 117 LEU B N   1 
ATOM   2709 C CA  . LEU B 2 117 ? 110.476 131.712 98.480  1.00 13.60  ? 117 LEU B CA  1 
ATOM   2710 C C   . LEU B 2 117 ? 109.007 131.820 98.103  1.00 13.60  ? 117 LEU B C   1 
ATOM   2711 O O   . LEU B 2 117 ? 108.494 130.936 97.412  1.00 13.60  ? 117 LEU B O   1 
ATOM   2712 C CB  . LEU B 2 117 ? 110.672 130.545 99.445  1.00 13.60  ? 117 LEU B CB  1 
ATOM   2713 C CG  . LEU B 2 117 ? 112.120 130.142 99.727  1.00 13.60  ? 117 LEU B CG  1 
ATOM   2714 C CD1 . LEU B 2 117 ? 112.178 129.118 100.842 1.00 13.60  ? 117 LEU B CD1 1 
ATOM   2715 C CD2 . LEU B 2 117 ? 112.782 129.600 98.480  1.00 13.60  ? 117 LEU B CD2 1 
ATOM   2716 N N   . ASP B 2 118 ? 108.317 132.868 98.544  1.00 13.93  ? 118 ASP B N   1 
ATOM   2717 C CA  . ASP B 2 118 ? 106.914 133.044 98.197  1.00 13.93  ? 118 ASP B CA  1 
ATOM   2718 C C   . ASP B 2 118 ? 106.713 133.502 96.759  1.00 13.93  ? 118 ASP B C   1 
ATOM   2719 O O   . ASP B 2 118 ? 105.567 133.562 96.301  1.00 13.93  ? 118 ASP B O   1 
ATOM   2720 C CB  . ASP B 2 118 ? 106.262 134.048 99.146  1.00 13.93  ? 118 ASP B CB  1 
ATOM   2721 C CG  . ASP B 2 118 ? 106.906 135.418 99.075  1.00 13.93  ? 118 ASP B CG  1 
ATOM   2722 O OD1 . ASP B 2 118 ? 107.908 135.569 98.345  1.00 13.93  ? 118 ASP B OD1 1 
ATOM   2723 O OD2 . ASP B 2 118 ? 106.412 136.346 99.750  1.00 13.93  ? 118 ASP B OD2 1 
ATOM   2724 N N   . ASN B 2 119 ? 107.803 133.822 96.052  1.00 14.79  ? 119 ASN B N   1 
ATOM   2725 C CA  . ASN B 2 119 ? 107.763 134.248 94.625  1.00 14.79  ? 119 ASN B CA  1 
ATOM   2726 C C   . ASN B 2 119 ? 106.939 135.531 94.482  1.00 14.79  ? 119 ASN B C   1 
ATOM   2727 O O   . ASN B 2 119 ? 106.345 135.715 93.405  1.00 14.79  ? 119 ASN B O   1 
ATOM   2728 C CB  . ASN B 2 119 ? 107.239 133.129 93.720  1.00 14.79  ? 119 ASN B CB  1 
ATOM   2729 C CG  . ASN B 2 119 ? 108.127 131.903 93.726  1.00 14.79  ? 119 ASN B CG  1 
ATOM   2730 O OD1 . ASN B 2 119 ? 108.950 131.730 94.620  1.00 14.79  ? 119 ASN B OD1 1 
ATOM   2731 N ND2 . ASN B 2 119 ? 107.972 131.048 92.729  1.00 14.79  ? 119 ASN B ND2 1 
ATOM   2732 N N   . ILE B 2 120 ? 106.898 136.387 95.509  1.00 14.82  ? 120 ILE B N   1 
ATOM   2733 C CA  . ILE B 2 120 ? 106.182 137.656 95.466  1.00 14.82  ? 120 ILE B CA  1 
ATOM   2734 C C   . ILE B 2 120 ? 107.075 138.746 96.038  1.00 14.82  ? 120 ILE B C   1 
ATOM   2735 O O   . ILE B 2 120 ? 107.783 138.528 97.026  1.00 14.82  ? 120 ILE B O   1 
ATOM   2736 C CB  . ILE B 2 120 ? 104.853 137.590 96.246  1.00 14.82  ? 120 ILE B CB  1 
ATOM   2737 C CG1 . ILE B 2 120 ? 103.860 136.681 95.525  1.00 14.82  ? 120 ILE B CG1 1 
ATOM   2738 C CG2 . ILE B 2 120 ? 104.272 138.979 96.419  1.00 14.82  ? 120 ILE B CG2 1 
ATOM   2739 C CD1 . ILE B 2 120 ? 102.637 136.349 96.342  1.00 14.82  ? 120 ILE B CD1 1 
ATOM   2740 N N   . CYS B 2 121 ? 107.040 139.918 95.412  1.00 13.65  ? 121 CYS B N   1 
ATOM   2741 C CA  . CYS B 2 121 ? 107.711 141.108 95.917  1.00 13.65  ? 121 CYS B CA  1 
ATOM   2742 C C   . CYS B 2 121 ? 106.658 142.031 96.517  1.00 13.65  ? 121 CYS B C   1 
ATOM   2743 O O   . CYS B 2 121 ? 105.704 142.413 95.833  1.00 13.65  ? 121 CYS B O   1 
ATOM   2744 C CB  . CYS B 2 121 ? 108.481 141.816 94.804  1.00 13.65  ? 121 CYS B CB  1 
ATOM   2745 S SG  . CYS B 2 121 ? 109.750 142.953 95.383  1.00 13.65  ? 121 CYS B SG  1 
ATOM   2746 N N   . SER B 2 122 ? 106.829 142.381 97.788  1.00 11.39  ? 122 SER B N   1 
ATOM   2747 C CA  . SER B 2 122 ? 105.862 143.181 98.526  1.00 11.39  ? 122 SER B CA  1 
ATOM   2748 C C   . SER B 2 122 ? 106.456 144.546 98.829  1.00 11.39  ? 122 SER B C   1 
ATOM   2749 O O   . SER B 2 122 ? 107.582 144.637 99.326  1.00 11.39  ? 122 SER B O   1 
ATOM   2750 C CB  . SER B 2 122 ? 105.460 142.484 99.825  1.00 11.39  ? 122 SER B CB  1 
ATOM   2751 O OG  . SER B 2 122 ? 104.894 141.214 99.567  1.00 11.39  ? 122 SER B OG  1 
ATOM   2752 N N   . ILE B 2 123 ? 105.700 145.600 98.535  1.00 15.73  ? 123 ILE B N   1 
ATOM   2753 C CA  . ILE B 2 123 ? 106.126 146.976 98.766  1.00 15.73  ? 123 ILE B CA  1 
ATOM   2754 C C   . ILE B 2 123 ? 105.422 147.493 100.009 1.00 15.73  ? 123 ILE B C   1 
ATOM   2755 O O   . ILE B 2 123 ? 104.209 147.306 100.168 1.00 15.73  ? 123 ILE B O   1 
ATOM   2756 C CB  . ILE B 2 123 ? 105.816 147.870 97.554  1.00 15.73  ? 123 ILE B CB  1 
ATOM   2757 C CG1 . ILE B 2 123 ? 106.358 147.249 96.264  1.00 15.73  ? 123 ILE B CG1 1 
ATOM   2758 C CG2 . ILE B 2 123 ? 106.394 149.253 97.761  1.00 15.73  ? 123 ILE B CG2 1 
ATOM   2759 C CD1 . ILE B 2 123 ? 107.856 147.074 96.242  1.00 15.73  ? 123 ILE B CD1 1 
ATOM   2760 N N   . TYR B 2 124 ? 106.174 148.143 100.891 1.00 14.44  ? 124 TYR B N   1 
ATOM   2761 C CA  . TYR B 2 124 ? 105.649 148.653 102.149 1.00 14.44  ? 124 TYR B CA  1 
ATOM   2762 C C   . TYR B 2 124 ? 105.747 150.170 102.183 1.00 14.44  ? 124 TYR B C   1 
ATOM   2763 O O   . TYR B 2 124 ? 106.676 150.764 101.630 1.00 14.44  ? 124 TYR B O   1 
ATOM   2764 C CB  . TYR B 2 124 ? 106.400 148.067 103.343 1.00 14.44  ? 124 TYR B CB  1 
ATOM   2765 C CG  . TYR B 2 124 ? 106.059 146.627 103.631 1.00 14.44  ? 124 TYR B CG  1 
ATOM   2766 C CD1 . TYR B 2 124 ? 106.772 145.594 103.045 1.00 14.44  ? 124 TYR B CD1 1 
ATOM   2767 C CD2 . TYR B 2 124 ? 105.026 146.300 104.490 1.00 14.44  ? 124 TYR B CD2 1 
ATOM   2768 C CE1 . TYR B 2 124 ? 106.467 144.282 103.305 1.00 14.44  ? 124 TYR B CE1 1 
ATOM   2769 C CE2 . TYR B 2 124 ? 104.715 144.990 104.758 1.00 14.44  ? 124 TYR B CE2 1 
ATOM   2770 C CZ  . TYR B 2 124 ? 105.436 143.984 104.161 1.00 14.44  ? 124 TYR B CZ  1 
ATOM   2771 O OH  . TYR B 2 124 ? 105.125 142.672 104.426 1.00 14.44  ? 124 TYR B OH  1 
ATOM   2772 N N   . ASN B 2 125 ? 104.776 150.790 102.846 1.00 20.74  ? 125 ASN B N   1 
ATOM   2773 C CA  . ASN B 2 125 ? 104.690 152.237 102.977 1.00 20.74  ? 125 ASN B CA  1 
ATOM   2774 C C   . ASN B 2 125 ? 105.103 152.623 104.389 1.00 20.74  ? 125 ASN B C   1 
ATOM   2775 O O   . ASN B 2 125 ? 104.519 152.136 105.362 1.00 20.74  ? 125 ASN B O   1 
ATOM   2776 C CB  . ASN B 2 125 ? 103.273 152.723 102.679 1.00 20.74  ? 125 ASN B CB  1 
ATOM   2777 C CG  . ASN B 2 125 ? 103.212 154.206 102.402 1.00 20.74  ? 125 ASN B CG  1 
ATOM   2778 O OD1 . ASN B 2 125 ? 104.233 154.893 102.407 1.00 20.74  ? 125 ASN B OD1 1 
ATOM   2779 N ND2 . ASN B 2 125 ? 102.011 154.712 102.156 1.00 20.74  ? 125 ASN B ND2 1 
ATOM   2780 N N   . LEU B 2 126 ? 106.103 153.495 104.500 1.00 15.73  ? 126 LEU B N   1 
ATOM   2781 C CA  . LEU B 2 126 ? 106.612 153.916 105.798 1.00 15.73  ? 126 LEU B CA  1 
ATOM   2782 C C   . LEU B 2 126 ? 106.041 155.245 106.268 1.00 15.73  ? 126 LEU B C   1 
ATOM   2783 O O   . LEU B 2 126 ? 105.960 155.476 107.477 1.00 15.73  ? 126 LEU B O   1 
ATOM   2784 C CB  . LEU B 2 126 ? 108.138 154.026 105.758 1.00 15.73  ? 126 LEU B CB  1 
ATOM   2785 C CG  . LEU B 2 126 ? 108.916 152.751 105.434 1.00 15.73  ? 126 LEU B CG  1 
ATOM   2786 C CD1 . LEU B 2 126 ? 110.403 153.034 105.460 1.00 15.73  ? 126 LEU B CD1 1 
ATOM   2787 C CD2 . LEU B 2 126 ? 108.573 151.636 106.398 1.00 15.73  ? 126 LEU B CD2 1 
ATOM   2788 N N   . LYS B 2 127 ? 105.646 156.122 105.348 1.00 17.66  ? 127 LYS B N   1 
ATOM   2789 C CA  . LYS B 2 127 ? 105.165 157.461 105.680 1.00 17.66  ? 127 LYS B CA  1 
ATOM   2790 C C   . LYS B 2 127 ? 103.646 157.545 105.636 1.00 17.66  ? 127 LYS B C   1 
ATOM   2791 O O   . LYS B 2 127 ? 103.088 158.570 105.236 1.00 17.66  ? 127 LYS B O   1 
ATOM   2792 C CB  . LYS B 2 127 ? 105.778 158.492 104.737 1.00 17.66  ? 127 LYS B CB  1 
ATOM   2793 C CG  . LYS B 2 127 ? 107.297 158.445 104.647 1.00 17.66  ? 127 LYS B CG  1 
ATOM   2794 C CD  . LYS B 2 127 ? 107.958 159.051 105.869 1.00 17.66  ? 127 LYS B CD  1 
ATOM   2795 C CE  . LYS B 2 127 ? 109.470 158.967 105.774 1.00 17.66  ? 127 LYS B CE  1 
ATOM   2796 N NZ  . LYS B 2 127 ? 110.005 157.765 106.465 1.00 17.66  ? 127 LYS B NZ  1 
ATOM   2797 N N   . THR B 2 128 ? 102.959 156.460 105.996 1.00 30.21  ? 128 THR B N   1 
ATOM   2798 C CA  . THR B 2 128 ? 101.474 156.395 105.935 1.00 30.21  ? 128 THR B CA  1 
ATOM   2799 C C   . THR B 2 128 ? 100.881 157.587 106.689 1.00 30.21  ? 128 THR B C   1 
ATOM   2800 O O   . THR B 2 128 ? 101.593 158.148 107.545 1.00 30.21  ? 128 THR B O   1 
ATOM   2801 C CB  . THR B 2 128 ? 100.952 155.064 106.491 1.00 30.21  ? 128 THR B CB  1 
ATOM   2802 O OG1 . THR B 2 128 ? 101.149 155.078 107.903 1.00 30.21  ? 128 THR B OG1 1 
ATOM   2803 C CG2 . THR B 2 128 ? 101.637 153.862 105.879 1.00 30.21  ? 128 THR B CG2 1 
ATOM   2804 N N   . ARG B 2 129 ? 99.629  157.952 106.401 1.00 42.61  ? 129 ARG B N   1 
ATOM   2805 C CA  . ARG B 2 129 ? 98.948  159.098 107.062 1.00 42.61  ? 129 ARG B CA  1 
ATOM   2806 C C   . ARG B 2 129 ? 98.916  158.851 108.571 1.00 42.61  ? 129 ARG B C   1 
ATOM   2807 O O   . ARG B 2 129 ? 99.303  159.769 109.319 1.00 42.61  ? 129 ARG B O   1 
ATOM   2808 C CB  . ARG B 2 129 ? 97.533  159.274 106.504 1.00 42.61  ? 129 ARG B CB  1 
ATOM   2809 N N   . GLU B 2 130 ? 98.485  157.663 109.004 1.00 53.32  ? 130 GLU B N   1 
ATOM   2810 C CA  . GLU B 2 130 ? 98.443  157.295 110.444 1.00 53.32  ? 130 GLU B CA  1 
ATOM   2811 C C   . GLU B 2 130 ? 99.875  157.048 110.917 1.00 53.32  ? 130 GLU B C   1 
ATOM   2812 O O   . GLU B 2 130 ? 100.109 157.133 112.137 1.00 53.32  ? 130 GLU B O   1 
ATOM   2813 C CB  . GLU B 2 130 ? 97.567  156.060 110.655 1.00 53.32  ? 130 GLU B CB  1 
ATOM   2814 N N   . GLY B 2 131 ? 100.793 156.750 109.993 1.00 49.13  ? 131 GLY B N   1 
ATOM   2815 C CA  . GLY B 2 131 ? 102.205 156.472 110.318 1.00 49.13  ? 131 GLY B CA  1 
ATOM   2816 C C   . GLY B 2 131 ? 102.446 154.981 110.424 1.00 49.13  ? 131 GLY B C   1 
ATOM   2817 O O   . GLY B 2 131 ? 103.615 154.568 110.304 1.00 49.13  ? 131 GLY B O   1 
ATOM   2818 N N   . ASN B 2 132 ? 101.386 154.193 110.623 1.00 39.37  ? 132 ASN B N   1 
ATOM   2819 C CA  . ASN B 2 132 ? 101.482 152.714 110.723 1.00 39.37  ? 132 ASN B CA  1 
ATOM   2820 C C   . ASN B 2 132 ? 101.831 152.153 109.344 1.00 39.37  ? 132 ASN B C   1 
ATOM   2821 O O   . ASN B 2 132 ? 101.153 152.534 108.374 1.00 39.37  ? 132 ASN B O   1 
ATOM   2822 C CB  . ASN B 2 132 ? 100.189 152.104 111.266 1.00 39.37  ? 132 ASN B CB  1 
ATOM   2823 C CG  . ASN B 2 132 ? 98.994  152.373 110.377 1.00 39.37  ? 132 ASN B CG  1 
ATOM   2824 O OD1 . ASN B 2 132 ? 98.835  153.475 109.858 1.00 39.37  ? 132 ASN B OD1 1 
ATOM   2825 N ND2 . ASN B 2 132 ? 98.150  151.371 110.194 1.00 39.37  ? 132 ASN B ND2 1 
ATOM   2826 N N   . VAL B 2 133 ? 102.822 151.263 109.257 1.00 22.09  ? 133 VAL B N   1 
ATOM   2827 C CA  . VAL B 2 133 ? 103.258 150.689 107.989 1.00 22.09  ? 133 VAL B CA  1 
ATOM   2828 C C   . VAL B 2 133 ? 102.212 149.696 107.503 1.00 22.09  ? 133 VAL B C   1 
ATOM   2829 O O   . VAL B 2 133 ? 101.714 148.871 108.278 1.00 22.09  ? 133 VAL B O   1 
ATOM   2830 C CB  . VAL B 2 133 ? 104.631 150.020 108.143 1.00 22.09  ? 133 VAL B CB  1 
ATOM   2831 C CG1 . VAL B 2 133 ? 105.622 150.991 108.745 1.00 22.09  ? 133 VAL B CG1 1 
ATOM   2832 C CG2 . VAL B 2 133 ? 104.513 148.783 109.012 1.00 22.09  ? 133 VAL B CG2 1 
ATOM   2833 N N   . ARG B 2 134 ? 101.875 149.774 106.219 1.00 18.57  ? 134 ARG B N   1 
ATOM   2834 C CA  . ARG B 2 134 ? 100.854 148.928 105.622 1.00 18.57  ? 134 ARG B CA  1 
ATOM   2835 C C   . ARG B 2 134 ? 101.360 148.361 104.304 1.00 18.57  ? 134 ARG B C   1 
ATOM   2836 O O   . ARG B 2 134 ? 102.154 148.993 103.602 1.00 18.57  ? 134 ARG B O   1 
ATOM   2837 C CB  . ARG B 2 134 ? 99.557  149.714 105.390 1.00 18.57  ? 134 ARG B CB  1 
ATOM   2838 N N   . VAL B 2 135 ? 100.892 147.159 103.975 1.00 16.15  ? 135 VAL B N   1 
ATOM   2839 C CA  . VAL B 2 135 ? 101.236 146.528 102.703 1.00 16.15  ? 135 VAL B CA  1 
ATOM   2840 C C   . VAL B 2 135 ? 100.501 147.278 101.599 1.00 16.15  ? 135 VAL B C   1 
ATOM   2841 O O   . VAL B 2 135 ? 99.268  147.263 101.545 1.00 16.15  ? 135 VAL B O   1 
ATOM   2842 C CB  . VAL B 2 135 ? 100.875 145.039 102.693 1.00 16.15  ? 135 VAL B CB  1 
ATOM   2843 C CG1 . VAL B 2 135 ? 101.289 144.408 101.376 1.00 16.15  ? 135 VAL B CG1 1 
ATOM   2844 C CG2 . VAL B 2 135 ? 101.529 144.313 103.854 1.00 16.15  ? 135 VAL B CG2 1 
ATOM   2845 N N   . SER B 2 136 ? 101.250 147.929 100.711 1.00 18.27  ? 136 SER B N   1 
ATOM   2846 C CA  . SER B 2 136 ? 100.661 148.792 99.698  1.00 18.27  ? 136 SER B CA  1 
ATOM   2847 C C   . SER B 2 136 ? 100.621 148.168 98.309  1.00 18.27  ? 136 SER B C   1 
ATOM   2848 O O   . SER B 2 136 ? 99.982  148.734 97.419  1.00 18.27  ? 136 SER B O   1 
ATOM   2849 C CB  . SER B 2 136 ? 101.430 150.114 99.625  1.00 18.27  ? 136 SER B CB  1 
ATOM   2850 O OG  . SER B 2 136 ? 102.743 149.907 99.141  1.00 18.27  ? 136 SER B OG  1 
ATOM   2851 N N   . ARG B 2 137 ? 101.344 147.079 98.078  1.00 19.90  ? 137 ARG B N   1 
ATOM   2852 C CA  . ARG B 2 137 ? 101.416 146.505 96.713  1.00 19.90  ? 137 ARG B CA  1 
ATOM   2853 C C   . ARG B 2 137 ? 102.007 145.104 96.763  1.00 19.90  ? 137 ARG B C   1 
ATOM   2854 O O   . ARG B 2 137 ? 102.889 144.873 97.601  1.00 19.90  ? 137 ARG B O   1 
ATOM   2855 C CB  . ARG B 2 137 ? 102.254 147.423 95.816  1.00 19.90  ? 137 ARG B CB  1 
ATOM   2856 C CG  . ARG B 2 137 ? 102.726 146.793 94.513  1.00 19.90  ? 137 ARG B CG  1 
ATOM   2857 C CD  . ARG B 2 137 ? 101.598 146.675 93.510  1.00 19.90  ? 137 ARG B CD  1 
ATOM   2858 N NE  . ARG B 2 137 ? 101.292 147.955 92.890  1.00 19.90  ? 137 ARG B NE  1 
ATOM   2859 C CZ  . ARG B 2 137 ? 100.321 148.156 92.006  1.00 19.90  ? 137 ARG B CZ  1 
ATOM   2860 N NH1 . ARG B 2 137 ? 99.544  147.158 91.622  1.00 19.90  ? 137 ARG B NH1 1 
ATOM   2861 N NH2 . ARG B 2 137 ? 100.127 149.361 91.507  1.00 19.90  ? 137 ARG B NH2 1 
ATOM   2862 N N   . GLU B 2 138 ? 101.518 144.198 95.925  1.00 17.33  ? 138 GLU B N   1 
ATOM   2863 C CA  . GLU B 2 138 ? 102.074 142.856 95.792  1.00 17.33  ? 138 GLU B CA  1 
ATOM   2864 C C   . GLU B 2 138 ? 102.273 142.569 94.313  1.00 17.33  ? 138 GLU B C   1 
ATOM   2865 O O   . GLU B 2 138 ? 101.311 142.598 93.542  1.00 17.33  ? 138 GLU B O   1 
ATOM   2866 C CB  . GLU B 2 138 ? 101.156 141.807 96.420  1.00 17.33  ? 138 GLU B CB  1 
ATOM   2867 C CG  . GLU B 2 138 ? 101.097 141.865 97.931  1.00 17.33  ? 138 GLU B CG  1 
ATOM   2868 C CD  . GLU B 2 138 ? 100.479 140.623 98.533  1.00 17.33  ? 138 GLU B CD  1 
ATOM   2869 O OE1 . GLU B 2 138 ? 99.943  139.796 97.768  1.00 17.33  ? 138 GLU B OE1 1 
ATOM   2870 O OE2 . GLU B 2 138 ? 100.529 140.472 99.771  1.00 17.33  ? 138 GLU B OE2 1 
ATOM   2871 N N   . LEU B 2 139 ? 103.514 142.289 93.924  1.00 17.24  ? 139 LEU B N   1 
ATOM   2872 C CA  . LEU B 2 139 ? 103.869 142.048 92.530  1.00 17.24  ? 139 LEU B CA  1 
ATOM   2873 C C   . LEU B 2 139 ? 104.024 140.547 92.318  1.00 17.24  ? 139 LEU B C   1 
ATOM   2874 O O   . LEU B 2 139 ? 104.999 139.947 92.779  1.00 17.24  ? 139 LEU B O   1 
ATOM   2875 C CB  . LEU B 2 139 ? 105.154 142.786 92.164  1.00 17.24  ? 139 LEU B CB  1 
ATOM   2876 C CG  . LEU B 2 139 ? 105.230 144.260 92.563  1.00 17.24  ? 139 LEU B CG  1 
ATOM   2877 C CD1 . LEU B 2 139 ? 106.625 144.798 92.326  1.00 17.24  ? 139 LEU B CD1 1 
ATOM   2878 C CD2 . LEU B 2 139 ? 104.212 145.075 91.796  1.00 17.24  ? 139 LEU B CD2 1 
ATOM   2879 N N   . ALA B 2 140 ? 103.071 139.950 91.611  1.00 12.92  ? 140 ALA B N   1 
ATOM   2880 C CA  . ALA B 2 140 ? 103.065 138.522 91.333  1.00 12.92  ? 140 ALA B CA  1 
ATOM   2881 C C   . ALA B 2 140 ? 103.260 138.279 89.843  1.00 12.92  ? 140 ALA B C   1 
ATOM   2882 O O   . ALA B 2 140 ? 102.792 139.055 89.007  1.00 12.92  ? 140 ALA B O   1 
ATOM   2883 C CB  . ALA B 2 140 ? 101.755 137.881 91.794  1.00 12.92  ? 140 ALA B CB  1 
ATOM   2884 N N   . GLY B 2 141 ? 103.940 137.182 89.516  1.00 11.48  ? 141 GLY B N   1 
ATOM   2885 C CA  . GLY B 2 141 ? 104.218 136.867 88.128  1.00 11.48  ? 141 GLY B CA  1 
ATOM   2886 C C   . GLY B 2 141 ? 105.536 136.162 87.872  1.00 11.48  ? 141 GLY B C   1 
ATOM   2887 O O   . GLY B 2 141 ? 105.790 135.726 86.747  1.00 11.48  ? 141 GLY B O   1 
ATOM   2888 N N   . HIS B 2 142 ? 106.425 136.093 88.865  1.00 12.50  ? 142 HIS B N   1 
ATOM   2889 C CA  . HIS B 2 142 ? 107.711 135.353 88.741  1.00 12.50  ? 142 HIS B CA  1 
ATOM   2890 C C   . HIS B 2 142 ? 107.421 133.868 88.978  1.00 12.50  ? 142 HIS B C   1 
ATOM   2891 O O   . HIS B 2 142 ? 106.489 133.587 89.753  1.00 12.50  ? 142 HIS B O   1 
ATOM   2892 C CB  . HIS B 2 142 ? 108.766 135.920 89.699  1.00 12.50  ? 142 HIS B CB  1 
ATOM   2893 C CG  . HIS B 2 142 ? 109.783 136.786 89.036  1.00 12.50  ? 142 HIS B CG  1 
ATOM   2894 N ND1 . HIS B 2 142 ? 110.650 136.301 88.079  1.00 12.50  ? 142 HIS B ND1 1 
ATOM   2895 C CD2 . HIS B 2 142 ? 110.080 138.095 89.188  1.00 12.50  ? 142 HIS B CD2 1 
ATOM   2896 C CE1 . HIS B 2 142 ? 111.438 137.274 87.668  1.00 12.50  ? 142 HIS B CE1 1 
ATOM   2897 N NE2 . HIS B 2 142 ? 111.108 138.384 88.332  1.00 12.50  ? 142 HIS B NE2 1 
ATOM   2898 N N   . THR B 2 143 ? 108.168 132.954 88.353  1.00 12.33  ? 143 THR B N   1 
ATOM   2899 C CA  . THR B 2 143 ? 107.924 131.488 88.455  1.00 12.33  ? 143 THR B CA  1 
ATOM   2900 C C   . THR B 2 143 ? 109.007 130.821 89.307  1.00 12.33  ? 143 THR B C   1 
ATOM   2901 O O   . THR B 2 143 ? 109.170 129.596 89.178  1.00 12.33  ? 143 THR B O   1 
ATOM   2902 C CB  . THR B 2 143 ? 107.867 130.845 87.066  1.00 12.33  ? 143 THR B CB  1 
ATOM   2903 O OG1 . THR B 2 143 ? 109.206 130.691 86.597  1.00 12.33  ? 143 THR B OG1 1 
ATOM   2904 C CG2 . THR B 2 143 ? 107.067 131.659 86.074  1.00 12.33  ? 143 THR B CG2 1 
ATOM   2905 N N   . GLY B 2 144 ? 109.718 131.585 90.138  1.00 12.83  ? 144 GLY B N   1 
ATOM   2906 C CA  . GLY B 2 144 ? 110.776 131.046 91.012  1.00 12.83  ? 144 GLY B CA  1 
ATOM   2907 C C   . GLY B 2 144 ? 111.040 131.956 92.193  1.00 12.83  ? 144 GLY B C   1 
ATOM   2908 O O   . GLY B 2 144 ? 110.536 133.092 92.175  1.00 12.83  ? 144 GLY B O   1 
ATOM   2909 N N   . TYR B 2 145 ? 111.806 131.496 93.181  1.00 13.47  ? 145 TYR B N   1 
ATOM   2910 C CA  . TYR B 2 145 ? 112.155 132.297 94.380  1.00 13.47  ? 145 TYR B CA  1 
ATOM   2911 C C   . TYR B 2 145 ? 112.838 133.587 93.933  1.00 13.47  ? 145 TYR B C   1 
ATOM   2912 O O   . TYR B 2 145 ? 113.630 133.525 92.978  1.00 13.47  ? 145 TYR B O   1 
ATOM   2913 C CB  . TYR B 2 145 ? 113.059 131.495 95.318  1.00 13.47  ? 145 TYR B CB  1 
ATOM   2914 C CG  . TYR B 2 145 ? 114.430 131.185 94.773  1.00 13.47  ? 145 TYR B CG  1 
ATOM   2915 C CD1 . TYR B 2 145 ? 115.474 132.083 94.910  1.00 13.47  ? 145 TYR B CD1 1 
ATOM   2916 C CD2 . TYR B 2 145 ? 114.687 129.986 94.130  1.00 13.47  ? 145 TYR B CD2 1 
ATOM   2917 C CE1 . TYR B 2 145 ? 116.736 131.803 94.415  1.00 13.47  ? 145 TYR B CE1 1 
ATOM   2918 C CE2 . TYR B 2 145 ? 115.944 129.690 93.630  1.00 13.47  ? 145 TYR B CE2 1 
ATOM   2919 C CZ  . TYR B 2 145 ? 116.973 130.602 93.773  1.00 13.47  ? 145 TYR B CZ  1 
ATOM   2920 O OH  . TYR B 2 145 ? 118.215 130.320 93.284  1.00 13.47  ? 145 TYR B OH  1 
ATOM   2921 N N   . LEU B 2 146 ? 112.534 134.714 94.579  1.00 15.01  ? 146 LEU B N   1 
ATOM   2922 C CA  . LEU B 2 146 ? 113.190 136.012 94.270  1.00 15.01  ? 146 LEU B CA  1 
ATOM   2923 C C   . LEU B 2 146 ? 114.472 136.102 95.097  1.00 15.01  ? 146 LEU B C   1 
ATOM   2924 O O   . LEU B 2 146 ? 114.381 135.932 96.323  1.00 15.01  ? 146 LEU B O   1 
ATOM   2925 C CB  . LEU B 2 146 ? 112.232 137.166 94.580  1.00 15.01  ? 146 LEU B CB  1 
ATOM   2926 C CG  . LEU B 2 146 ? 112.678 138.532 94.063  1.00 15.01  ? 146 LEU B CG  1 
ATOM   2927 C CD1 . LEU B 2 146 ? 111.491 139.338 93.561  1.00 15.01  ? 146 LEU B CD1 1 
ATOM   2928 C CD2 . LEU B 2 146 ? 113.431 139.299 95.136  1.00 15.01  ? 146 LEU B CD2 1 
ATOM   2929 N N   . SER B 2 147 ? 115.614 136.354 94.462  1.00 13.52  ? 147 SER B N   1 
ATOM   2930 C CA  . SER B 2 147 ? 116.911 136.423 95.114  1.00 13.52  ? 147 SER B CA  1 
ATOM   2931 C C   . SER B 2 147 ? 117.500 137.824 95.181  1.00 13.52  ? 147 SER B C   1 
ATOM   2932 O O   . SER B 2 147 ? 118.549 138.001 95.808  1.00 13.52  ? 147 SER B O   1 
ATOM   2933 C CB  . SER B 2 147 ? 117.908 135.500 94.399  1.00 13.52  ? 147 SER B CB  1 
ATOM   2934 O OG  . SER B 2 147 ? 118.046 135.857 93.037  1.00 13.52  ? 147 SER B OG  1 
ATOM   2935 N N   . CYS B 2 148 ? 116.872 138.819 94.560  1.00 14.57  ? 148 CYS B N   1 
ATOM   2936 C CA  . CYS B 2 148 ? 117.381 140.180 94.642  1.00 14.57  ? 148 CYS B CA  1 
ATOM   2937 C C   . CYS B 2 148 ? 116.359 141.131 94.045  1.00 14.57  ? 148 CYS B C   1 
ATOM   2938 O O   . CYS B 2 148 ? 115.620 140.769 93.127  1.00 14.57  ? 148 CYS B O   1 
ATOM   2939 C CB  . CYS B 2 148 ? 118.723 140.327 93.918  1.00 14.57  ? 148 CYS B CB  1 
ATOM   2940 S SG  . CYS B 2 148 ? 119.697 141.743 94.461  1.00 14.57  ? 148 CYS B SG  1 
ATOM   2941 N N   . CYS B 2 149 ? 116.328 142.348 94.582  1.00 12.42  ? 149 CYS B N   1 
ATOM   2942 C CA  . CYS B 2 149 ? 115.466 143.400 94.072  1.00 12.42  ? 149 CYS B CA  1 
ATOM   2943 C C   . CYS B 2 149 ? 116.130 144.738 94.352  1.00 12.42  ? 149 CYS B C   1 
ATOM   2944 O O   . CYS B 2 149 ? 116.845 144.893 95.344  1.00 12.42  ? 149 CYS B O   1 
ATOM   2945 C CB  . CYS B 2 149 ? 114.075 143.349 94.708  1.00 12.42  ? 149 CYS B CB  1 
ATOM   2946 S SG  . CYS B 2 149 ? 114.067 143.623 96.485  1.00 12.42  ? 149 CYS B SG  1 
ATOM   2947 N N   . ARG B 2 150 ? 115.895 145.702 93.465  1.00 14.03  ? 150 ARG B N   1 
ATOM   2948 C CA  . ARG B 2 150 ? 116.515 147.014 93.588  1.00 14.03  ? 150 ARG B CA  1 
ATOM   2949 C C   . ARG B 2 150 ? 115.561 148.076 93.069  1.00 14.03  ? 150 ARG B C   1 
ATOM   2950 O O   . ARG B 2 150 ? 114.980 147.919 91.993  1.00 14.03  ? 150 ARG B O   1 
ATOM   2951 C CB  . ARG B 2 150 ? 117.839 147.070 92.822  1.00 14.03  ? 150 ARG B CB  1 
ATOM   2952 C CG  . ARG B 2 150 ? 118.977 146.320 93.492  1.00 14.03  ? 150 ARG B CG  1 
ATOM   2953 C CD  . ARG B 2 150 ? 119.464 147.045 94.730  1.00 14.03  ? 150 ARG B CD  1 
ATOM   2954 N NE  . ARG B 2 150 ? 120.604 146.380 95.350  1.00 14.03  ? 150 ARG B NE  1 
ATOM   2955 C CZ  . ARG B 2 150 ? 120.530 145.558 96.389  1.00 14.03  ? 150 ARG B CZ  1 
ATOM   2956 N NH1 . ARG B 2 150 ? 119.373 145.247 96.948  1.00 14.03  ? 150 ARG B NH1 1 
ATOM   2957 N NH2 . ARG B 2 150 ? 121.649 145.033 96.879  1.00 14.03  ? 150 ARG B NH2 1 
ATOM   2958 N N   . PHE B 2 151 ? 115.409 149.152 93.835  1.00 12.99  ? 151 PHE B N   1 
ATOM   2959 C CA  . PHE B 2 151 ? 114.543 150.254 93.451  1.00 12.99  ? 151 PHE B CA  1 
ATOM   2960 C C   . PHE B 2 151 ? 115.225 151.120 92.401  1.00 12.99  ? 151 PHE B C   1 
ATOM   2961 O O   . PHE B 2 151 ? 116.390 151.497 92.558  1.00 12.99  ? 151 PHE B O   1 
ATOM   2962 C CB  . PHE B 2 151 ? 114.200 151.108 94.669  1.00 12.99  ? 151 PHE B CB  1 
ATOM   2963 C CG  . PHE B 2 151 ? 112.934 150.710 95.361  1.00 12.99  ? 151 PHE B CG  1 
ATOM   2964 C CD1 . PHE B 2 151 ? 111.713 151.154 94.903  1.00 12.99  ? 151 PHE B CD1 1 
ATOM   2965 C CD2 . PHE B 2 151 ? 112.968 149.912 96.487  1.00 12.99  ? 151 PHE B CD2 1 
ATOM   2966 C CE1 . PHE B 2 151 ? 110.549 150.798 95.544  1.00 12.99  ? 151 PHE B CE1 1 
ATOM   2967 C CE2 . PHE B 2 151 ? 111.807 149.553 97.131  1.00 12.99  ? 151 PHE B CE2 1 
ATOM   2968 C CZ  . PHE B 2 151 ? 110.598 149.996 96.659  1.00 12.99  ? 151 PHE B CZ  1 
ATOM   2969 N N   . LEU B 2 152 ? 114.500 151.437 91.330  1.00 17.31  ? 152 LEU B N   1 
ATOM   2970 C CA  . LEU B 2 152 ? 114.936 152.479 90.409  1.00 17.31  ? 152 LEU B CA  1 
ATOM   2971 C C   . LEU B 2 152 ? 114.456 153.849 90.865  1.00 17.31  ? 152 LEU B C   1 
ATOM   2972 O O   . LEU B 2 152 ? 115.224 154.817 90.850  1.00 17.31  ? 152 LEU B O   1 
ATOM   2973 C CB  . LEU B 2 152 ? 114.418 152.190 88.999  1.00 17.31  ? 152 LEU B CB  1 
ATOM   2974 C CG  . LEU B 2 152 ? 115.258 151.234 88.157  1.00 17.31  ? 152 LEU B CG  1 
ATOM   2975 C CD1 . LEU B 2 152 ? 114.994 149.800 88.561  1.00 17.31  ? 152 LEU B CD1 1 
ATOM   2976 C CD2 . LEU B 2 152 ? 114.964 151.435 86.684  1.00 17.31  ? 152 LEU B CD2 1 
ATOM   2977 N N   . ASP B 2 153 ? 113.196 153.938 91.270  1.00 24.01  ? 153 ASP B N   1 
ATOM   2978 C CA  . ASP B 2 153 ? 112.627 155.126 91.889  1.00 24.01  ? 153 ASP B CA  1 
ATOM   2979 C C   . ASP B 2 153 ? 111.414 154.671 92.694  1.00 24.01  ? 153 ASP B C   1 
ATOM   2980 O O   . ASP B 2 153 ? 111.226 153.474 92.933  1.00 24.01  ? 153 ASP B O   1 
ATOM   2981 C CB  . ASP B 2 153 ? 112.283 156.181 90.834  1.00 24.01  ? 153 ASP B CB  1 
ATOM   2982 C CG  . ASP B 2 153 ? 111.249 155.701 89.843  1.00 24.01  ? 153 ASP B CG  1 
ATOM   2983 O OD1 . ASP B 2 153 ? 110.128 155.359 90.269  1.00 24.01  ? 153 ASP B OD1 1 
ATOM   2984 O OD2 . ASP B 2 153 ? 111.555 155.669 88.633  1.00 24.01  ? 153 ASP B OD2 1 
ATOM   2985 N N   . ASP B 2 154 ? 110.582 155.622 93.114  1.00 19.69  ? 154 ASP B N   1 
ATOM   2986 C CA  . ASP B 2 154 ? 109.426 155.273 93.929  1.00 19.69  ? 154 ASP B CA  1 
ATOM   2987 C C   . ASP B 2 154 ? 108.367 154.498 93.156  1.00 19.69  ? 154 ASP B C   1 
ATOM   2988 O O   . ASP B 2 154 ? 107.430 153.986 93.776  1.00 19.69  ? 154 ASP B O   1 
ATOM   2989 C CB  . ASP B 2 154 ? 108.799 156.534 94.522  1.00 19.69  ? 154 ASP B CB  1 
ATOM   2990 C CG  . ASP B 2 154 ? 108.314 157.497 93.461  1.00 19.69  ? 154 ASP B CG  1 
ATOM   2991 O OD1 . ASP B 2 154 ? 108.796 157.410 92.313  1.00 19.69  ? 154 ASP B OD1 1 
ATOM   2992 O OD2 . ASP B 2 154 ? 107.448 158.341 93.774  1.00 19.69  ? 154 ASP B OD2 1 
ATOM   2993 N N   . ASN B 2 155 ? 108.488 154.399 91.829  1.00 26.94  ? 155 ASN B N   1 
ATOM   2994 C CA  . ASN B 2 155 ? 107.476 153.750 91.005  1.00 26.94  ? 155 ASN B CA  1 
ATOM   2995 C C   . ASN B 2 155 ? 108.067 152.763 90.004  1.00 26.94  ? 155 ASN B C   1 
ATOM   2996 O O   . ASN B 2 155 ? 107.448 152.515 88.964  1.00 26.94  ? 155 ASN B O   1 
ATOM   2997 C CB  . ASN B 2 155 ? 106.648 154.804 90.265  1.00 26.94  ? 155 ASN B CB  1 
ATOM   2998 C CG  . ASN B 2 155 ? 105.304 154.281 89.825  1.00 26.94  ? 155 ASN B CG  1 
ATOM   2999 O OD1 . ASN B 2 155 ? 105.051 153.081 89.864  1.00 26.94  ? 155 ASN B OD1 1 
ATOM   3000 N ND2 . ASN B 2 155 ? 104.427 155.184 89.409  1.00 26.94  ? 155 ASN B ND2 1 
ATOM   3001 N N   . GLN B 2 156 ? 109.242 152.202 90.281  1.00 18.99  ? 156 GLN B N   1 
ATOM   3002 C CA  . GLN B 2 156 ? 109.847 151.185 89.434  1.00 18.99  ? 156 GLN B CA  1 
ATOM   3003 C C   . GLN B 2 156 ? 110.796 150.344 90.272  1.00 18.99  ? 156 GLN B C   1 
ATOM   3004 O O   . GLN B 2 156 ? 111.461 150.852 91.178  1.00 18.99  ? 156 GLN B O   1 
ATOM   3005 C CB  . GLN B 2 156 ? 110.613 151.798 88.259  1.00 18.99  ? 156 GLN B CB  1 
ATOM   3006 C CG  . GLN B 2 156 ? 109.732 152.345 87.160  1.00 18.99  ? 156 GLN B CG  1 
ATOM   3007 C CD  . GLN B 2 156 ? 110.436 152.376 85.821  1.00 18.99  ? 156 GLN B CD  1 
ATOM   3008 O OE1 . GLN B 2 156 ? 109.993 151.748 84.860  1.00 18.99  ? 156 GLN B OE1 1 
ATOM   3009 N NE2 . GLN B 2 156 ? 111.543 153.104 85.751  1.00 18.99  ? 156 GLN B NE2 1 
ATOM   3010 N N   . ILE B 2 157 ? 110.863 149.055 89.958  1.00 15.83  ? 157 ILE B N   1 
ATOM   3011 C CA  . ILE B 2 157 ? 111.728 148.132 90.684  1.00 15.83  ? 157 ILE B CA  1 
ATOM   3012 C C   . ILE B 2 157 ? 112.135 147.010 89.741  1.00 15.83  ? 157 ILE B C   1 
ATOM   3013 O O   . ILE B 2 157 ? 111.340 146.563 88.912  1.00 15.83  ? 157 ILE B O   1 
ATOM   3014 C CB  . ILE B 2 157 ? 111.025 147.588 91.946  1.00 15.83  ? 157 ILE B CB  1 
ATOM   3015 C CG1 . ILE B 2 157 ? 111.962 146.670 92.727  1.00 15.83  ? 157 ILE B CG1 1 
ATOM   3016 C CG2 . ILE B 2 157 ? 109.758 146.851 91.575  1.00 15.83  ? 157 ILE B CG2 1 
ATOM   3017 C CD1 . ILE B 2 157 ? 111.519 146.423 94.146  1.00 15.83  ? 157 ILE B CD1 1 
ATOM   3018 N N   . VAL B 2 158 ? 113.381 146.560 89.870  1.00 15.24  ? 158 VAL B N   1 
ATOM   3019 C CA  . VAL B 2 158 ? 113.930 145.483 89.052  1.00 15.24  ? 158 VAL B CA  1 
ATOM   3020 C C   . VAL B 2 158 ? 114.241 144.305 89.962  1.00 15.24  ? 158 VAL B C   1 
ATOM   3021 O O   . VAL B 2 158 ? 114.901 144.468 90.994  1.00 15.24  ? 158 VAL B O   1 
ATOM   3022 C CB  . VAL B 2 158 ? 115.190 145.932 88.288  1.00 15.24  ? 158 VAL B CB  1 
ATOM   3023 C CG1 . VAL B 2 158 ? 116.339 146.176 89.246  1.00 15.24  ? 158 VAL B CG1 1 
ATOM   3024 C CG2 . VAL B 2 158 ? 115.574 144.899 87.243  1.00 15.24  ? 158 VAL B CG2 1 
ATOM   3025 N N   . THR B 2 159 ? 113.762 143.121 89.582  1.00 14.60  ? 159 THR B N   1 
ATOM   3026 C CA  . THR B 2 159 ? 113.905 141.921 90.392  1.00 14.60  ? 159 THR B CA  1 
ATOM   3027 C C   . THR B 2 159 ? 114.515 140.803 89.562  1.00 14.60  ? 159 THR B C   1 
ATOM   3028 O O   . THR B 2 159 ? 114.336 140.744 88.343  1.00 14.60  ? 159 THR B O   1 
ATOM   3029 C CB  . THR B 2 159 ? 112.558 141.457 90.947  1.00 14.60  ? 159 THR B CB  1 
ATOM   3030 O OG1 . THR B 2 159 ? 111.739 140.980 89.875  1.00 14.60  ? 159 THR B OG1 1 
ATOM   3031 C CG2 . THR B 2 159 ? 111.848 142.596 91.646  1.00 14.60  ? 159 THR B CG2 1 
ATOM   3032 N N   . SER B 2 160 ? 115.241 139.915 90.237  1.00 12.30  ? 160 SER B N   1 
ATOM   3033 C CA  . SER B 2 160 ? 115.833 138.737 89.619  1.00 12.30  ? 160 SER B CA  1 
ATOM   3034 C C   . SER B 2 160 ? 115.413 137.509 90.406  1.00 12.30  ? 160 SER B C   1 
ATOM   3035 O O   . SER B 2 160 ? 115.562 137.475 91.631  1.00 12.30  ? 160 SER B O   1 
ATOM   3036 C CB  . SER B 2 160 ? 117.358 138.835 89.579  1.00 12.30  ? 160 SER B CB  1 
ATOM   3037 O OG  . SER B 2 160 ? 117.917 138.511 90.838  1.00 12.30  ? 160 SER B OG  1 
ATOM   3038 N N   . SER B 2 161 ? 114.903 136.489 89.712  1.00 11.81  ? 161 SER B N   1 
ATOM   3039 C CA  . SER B 2 161 ? 114.428 135.235 90.349  1.00 11.81  ? 161 SER B CA  1 
ATOM   3040 C C   . SER B 2 161 ? 115.248 134.049 89.843  1.00 11.81  ? 161 SER B C   1 
ATOM   3041 O O   . SER B 2 161 ? 115.939 134.213 88.821  1.00 11.81  ? 161 SER B O   1 
ATOM   3042 C CB  . SER B 2 161 ? 112.964 135.047 90.085  1.00 11.81  ? 161 SER B CB  1 
ATOM   3043 O OG  . SER B 2 161 ? 112.604 133.677 90.148  1.00 11.81  ? 161 SER B OG  1 
ATOM   3044 N N   . GLY B 2 162 ? 115.179 132.903 90.525  1.00 12.17  ? 162 GLY B N   1 
ATOM   3045 C CA  . GLY B 2 162 ? 115.926 131.689 90.142  1.00 12.17  ? 162 GLY B CA  1 
ATOM   3046 C C   . GLY B 2 162 ? 115.393 131.076 88.862  1.00 12.17  ? 162 GLY B C   1 
ATOM   3047 O O   . GLY B 2 162 ? 116.023 130.126 88.370  1.00 12.17  ? 162 GLY B O   1 
ATOM   3048 N N   . ASP B 2 163 ? 114.281 131.586 88.329  1.00 12.19  ? 163 ASP B N   1 
ATOM   3049 C CA  . ASP B 2 163 ? 113.693 131.093 87.055  1.00 12.19  ? 163 ASP B CA  1 
ATOM   3050 C C   . ASP B 2 163 ? 114.503 131.621 85.869  1.00 12.19  ? 163 ASP B C   1 
ATOM   3051 O O   . ASP B 2 163 ? 113.913 131.675 84.780  1.00 12.19  ? 163 ASP B O   1 
ATOM   3052 C CB  . ASP B 2 163 ? 112.219 131.484 86.940  1.00 12.19  ? 163 ASP B CB  1 
ATOM   3053 C CG  . ASP B 2 163 ? 111.984 132.982 86.891  1.00 12.19  ? 163 ASP B CG  1 
ATOM   3054 O OD1 . ASP B 2 163 ? 112.801 133.716 87.472  1.00 12.19  ? 163 ASP B OD1 1 
ATOM   3055 O OD2 . ASP B 2 163 ? 110.986 133.397 86.271  1.00 12.19  ? 163 ASP B OD2 1 
ATOM   3056 N N   . THR B 2 164 ? 115.755 132.056 86.067  1.00 13.85  ? 164 THR B N   1 
ATOM   3057 C CA  . THR B 2 164 ? 116.650 132.485 84.994  1.00 13.85  ? 164 THR B CA  1 
ATOM   3058 C C   . THR B 2 164 ? 116.132 133.718 84.259  1.00 13.85  ? 164 THR B C   1 
ATOM   3059 O O   . THR B 2 164 ? 116.356 133.863 83.057  1.00 13.85  ? 164 THR B O   1 
ATOM   3060 C CB  . THR B 2 164 ? 116.891 131.355 83.987  1.00 13.85  ? 164 THR B CB  1 
ATOM   3061 O OG1 . THR B 2 164 ? 115.679 131.074 83.280  1.00 13.85  ? 164 THR B OG1 1 
ATOM   3062 C CG2 . THR B 2 164 ? 117.371 130.091 84.683  1.00 13.85  ? 164 THR B CG2 1 
ATOM   3063 N N   . THR B 2 165 ? 115.443 134.620 84.956  1.00 12.36  ? 165 THR B N   1 
ATOM   3064 C CA  . THR B 2 165 ? 114.918 135.826 84.332  1.00 12.36  ? 165 THR B CA  1 
ATOM   3065 C C   . THR B 2 165 ? 114.972 136.986 85.312  1.00 12.36  ? 165 THR B C   1 
ATOM   3066 O O   . THR B 2 165 ? 114.813 136.810 86.522  1.00 12.36  ? 165 THR B O   1 
ATOM   3067 C CB  . THR B 2 165 ? 113.471 135.644 83.856  1.00 12.36  ? 165 THR B CB  1 
ATOM   3068 O OG1 . THR B 2 165 ? 112.614 135.448 84.986  1.00 12.36  ? 165 THR B OG1 1 
ATOM   3069 C CG2 . THR B 2 165 ? 113.353 134.457 82.919  1.00 12.36  ? 165 THR B CG2 1 
ATOM   3070 N N   . CYS B 2 166 ? 115.197 138.178 84.767  1.00 14.17  ? 166 CYS B N   1 
ATOM   3071 C CA  . CYS B 2 166 ? 115.084 139.431 85.497  1.00 14.17  ? 166 CYS B CA  1 
ATOM   3072 C C   . CYS B 2 166 ? 113.939 140.238 84.901  1.00 14.17  ? 166 CYS B C   1 
ATOM   3073 O O   . CYS B 2 166 ? 113.719 140.213 83.687  1.00 14.17  ? 166 CYS B O   1 
ATOM   3074 C CB  . CYS B 2 166 ? 116.386 140.232 85.429  1.00 14.17  ? 166 CYS B CB  1 
ATOM   3075 S SG  . CYS B 2 166 ? 117.866 139.258 85.747  1.00 14.17  ? 166 CYS B SG  1 
ATOM   3076 N N   . ALA B 2 167 ? 113.205 140.946 85.757  1.00 13.98  ? 167 ALA B N   1 
ATOM   3077 C CA  . ALA B 2 167 ? 111.998 141.644 85.346  1.00 13.98  ? 167 ALA B CA  1 
ATOM   3078 C C   . ALA B 2 167 ? 112.037 143.089 85.819  1.00 13.98  ? 167 ALA B C   1 
ATOM   3079 O O   . ALA B 2 167 ? 112.732 143.435 86.775  1.00 13.98  ? 167 ALA B O   1 
ATOM   3080 C CB  . ALA B 2 167 ? 110.744 140.958 85.897  1.00 13.98  ? 167 ALA B CB  1 
ATOM   3081 N N   . LEU B 2 168 ? 111.277 143.930 85.124  1.00 15.23  ? 168 LEU B N   1 
ATOM   3082 C CA  . LEU B 2 168 ? 111.080 145.325 85.490  1.00 15.23  ? 168 LEU B CA  1 
ATOM   3083 C C   . LEU B 2 168 ? 109.596 145.547 85.736  1.00 15.23  ? 168 LEU B C   1 
ATOM   3084 O O   . LEU B 2 168 ? 108.766 145.180 84.900  1.00 15.23  ? 168 LEU B O   1 
ATOM   3085 C CB  . LEU B 2 168 ? 111.588 146.260 84.392  1.00 15.23  ? 168 LEU B CB  1 
ATOM   3086 C CG  . LEU B 2 168 ? 111.609 147.748 84.734  1.00 15.23  ? 168 LEU B CG  1 
ATOM   3087 C CD1 . LEU B 2 168 ? 112.896 148.114 85.443  1.00 15.23  ? 168 LEU B CD1 1 
ATOM   3088 C CD2 . LEU B 2 168 ? 111.436 148.580 83.479  1.00 15.23  ? 168 LEU B CD2 1 
ATOM   3089 N N   . TRP B 2 169 ? 109.265 146.146 86.875  1.00 15.04  ? 169 TRP B N   1 
ATOM   3090 C CA  . TRP B 2 169 ? 107.889 146.256 87.327  1.00 15.04  ? 169 TRP B CA  1 
ATOM   3091 C C   . TRP B 2 169 ? 107.435 147.708 87.350  1.00 15.04  ? 169 TRP B C   1 
ATOM   3092 O O   . TRP B 2 169 ? 108.239 148.629 87.514  1.00 15.04  ? 169 TRP B O   1 
ATOM   3093 C CB  . TRP B 2 169 ? 107.724 145.654 88.723  1.00 15.04  ? 169 TRP B CB  1 
ATOM   3094 C CG  . TRP B 2 169 ? 107.975 144.184 88.777  1.00 15.04  ? 169 TRP B CG  1 
ATOM   3095 C CD1 . TRP B 2 169 ? 109.164 143.564 89.019  1.00 15.04  ? 169 TRP B CD1 1 
ATOM   3096 C CD2 . TRP B 2 169 ? 107.011 143.143 88.588  1.00 15.04  ? 169 TRP B CD2 1 
ATOM   3097 N NE1 . TRP B 2 169 ? 109.002 142.202 88.991  1.00 15.04  ? 169 TRP B NE1 1 
ATOM   3098 C CE2 . TRP B 2 169 ? 107.688 141.919 88.728  1.00 15.04  ? 169 TRP B CE2 1 
ATOM   3099 C CE3 . TRP B 2 169 ? 105.643 143.129 88.313  1.00 15.04  ? 169 TRP B CE3 1 
ATOM   3100 C CZ2 . TRP B 2 169 ? 107.044 140.695 88.603  1.00 15.04  ? 169 TRP B CZ2 1 
ATOM   3101 C CZ3 . TRP B 2 169 ? 105.008 141.916 88.189  1.00 15.04  ? 169 TRP B CZ3 1 
ATOM   3102 C CH2 . TRP B 2 169 ? 105.706 140.715 88.333  1.00 15.04  ? 169 TRP B CH2 1 
ATOM   3103 N N   . ASP B 2 170 ? 106.158 147.968 87.082  1.00 16.81  ? 170 ASP B N   1 
ATOM   3104 C CA  . ASP B 2 170 ? 105.602 149.344 87.161  1.00 16.81  ? 170 ASP B CA  1 
ATOM   3105 C C   . ASP B 2 170 ? 104.818 149.420 88.466  1.00 16.81  ? 170 ASP B C   1 
ATOM   3106 O O   . ASP B 2 170 ? 103.659 148.976 88.464  1.00 16.81  ? 170 ASP B O   1 
ATOM   3107 C CB  . ASP B 2 170 ? 104.734 149.684 85.951  1.00 16.81  ? 170 ASP B CB  1 
ATOM   3108 C CG  . ASP B 2 170 ? 103.819 150.871 86.189  1.00 16.81  ? 170 ASP B CG  1 
ATOM   3109 O OD1 . ASP B 2 170 ? 104.335 151.938 86.573  1.00 16.81  ? 170 ASP B OD1 1 
ATOM   3110 O OD2 . ASP B 2 170 ? 102.599 150.714 85.997  1.00 16.81  ? 170 ASP B OD2 1 
ATOM   3111 N N   . ILE B 2 171 ? 105.405 149.962 89.531  1.00 20.04  ? 171 ILE B N   1 
ATOM   3112 C CA  . ILE B 2 171 ? 104.761 149.964 90.878  1.00 20.04  ? 171 ILE B CA  1 
ATOM   3113 C C   . ILE B 2 171 ? 103.419 150.698 90.788  1.00 20.04  ? 171 ILE B C   1 
ATOM   3114 O O   . ILE B 2 171 ? 102.597 150.507 91.701  1.00 20.04  ? 171 ILE B O   1 
ATOM   3115 C CB  . ILE B 2 171 ? 105.704 150.579 91.929  1.00 20.04  ? 171 ILE B CB  1 
ATOM   3116 C CG1 . ILE B 2 171 ? 107.031 149.820 92.022  1.00 20.04  ? 171 ILE B CG1 1 
ATOM   3117 C CG2 . ILE B 2 171 ? 105.016 150.666 93.280  1.00 20.04  ? 171 ILE B CG2 1 
ATOM   3118 C CD1 . ILE B 2 171 ? 108.106 150.554 92.787  1.00 20.04  ? 171 ILE B CD1 1 
ATOM   3119 N N   . GLU B 2 172 ? 103.194 151.491 89.738  1.00 27.72  ? 172 GLU B N   1 
ATOM   3120 C CA  . GLU B 2 172 ? 101.942 152.272 89.553  1.00 27.72  ? 172 GLU B CA  1 
ATOM   3121 C C   . GLU B 2 172 ? 100.739 151.344 89.382  1.00 27.72  ? 172 GLU B C   1 
ATOM   3122 O O   . GLU B 2 172 ? 99.727  151.581 90.067  1.00 27.72  ? 172 GLU B O   1 
ATOM   3123 C CB  . GLU B 2 172 ? 102.051 153.146 88.304  1.00 27.72  ? 172 GLU B CB  1 
ATOM   3124 N N   . THR B 2 173 ? 100.826 150.351 88.493  1.00 31.18  ? 173 THR B N   1 
ATOM   3125 C CA  . THR B 2 173 ? 99.714  149.411 88.193  1.00 31.18  ? 173 THR B CA  1 
ATOM   3126 C C   . THR B 2 173 ? 100.122 147.982 88.549  1.00 31.18  ? 173 THR B C   1 
ATOM   3127 O O   . THR B 2 173 ? 99.262  147.090 88.440  1.00 31.18  ? 173 THR B O   1 
ATOM   3128 C CB  . THR B 2 173 ? 99.328  149.507 86.715  1.00 31.18  ? 173 THR B CB  1 
ATOM   3129 O OG1 . THR B 2 173 ? 100.323 148.811 85.965  1.00 31.18  ? 173 THR B OG1 1 
ATOM   3130 C CG2 . THR B 2 173 ? 99.220  150.935 86.231  1.00 31.18  ? 173 THR B CG2 1 
ATOM   3131 N N   . GLY B 2 174 ? 101.371 147.768 88.969  1.00 23.54  ? 174 GLY B N   1 
ATOM   3132 C CA  . GLY B 2 174 ? 101.887 146.428 89.306  1.00 23.54  ? 174 GLY B CA  1 
ATOM   3133 C C   . GLY B 2 174 ? 101.772 145.472 88.133  1.00 23.54  ? 174 GLY B C   1 
ATOM   3134 O O   . GLY B 2 174 ? 101.293 144.343 88.356  1.00 23.54  ? 174 GLY B O   1 
ATOM   3135 N N   . GLN B 2 175 ? 102.178 145.892 86.930  1.00 21.69  ? 175 GLN B N   1 
ATOM   3136 C CA  . GLN B 2 175 ? 102.148 145.035 85.713  1.00 21.69  ? 175 GLN B CA  1 
ATOM   3137 C C   . GLN B 2 175 ? 103.570 144.908 85.176  1.00 21.69  ? 175 GLN B C   1 
ATOM   3138 O O   . GLN B 2 175 ? 104.230 145.954 85.049  1.00 21.69  ? 175 GLN B O   1 
ATOM   3139 C CB  . GLN B 2 175 ? 101.236 145.632 84.644  1.00 21.69  ? 175 GLN B CB  1 
ATOM   3140 C CG  . GLN B 2 175 ? 99.857  144.993 84.603  1.00 21.69  ? 175 GLN B CG  1 
ATOM   3141 C CD  . GLN B 2 175 ? 99.046  145.340 85.826  1.00 21.69  ? 175 GLN B CD  1 
ATOM   3142 O OE1 . GLN B 2 175 ? 98.834  144.513 86.711  1.00 21.69  ? 175 GLN B OE1 1 
ATOM   3143 N NE2 . GLN B 2 175 ? 98.590  146.579 85.886  1.00 21.69  ? 175 GLN B NE2 1 
ATOM   3144 N N   . GLN B 2 176 ? 104.034 143.695 84.861  1.00 16.81  ? 176 GLN B N   1 
ATOM   3145 C CA  . GLN B 2 176 ? 105.412 143.524 84.426  1.00 16.81  ? 176 GLN B CA  1 
ATOM   3146 C C   . GLN B 2 176 ? 105.617 144.239 83.099  1.00 16.81  ? 176 GLN B C   1 
ATOM   3147 O O   . GLN B 2 176 ? 104.860 144.031 82.147  1.00 16.81  ? 176 GLN B O   1 
ATOM   3148 C CB  . GLN B 2 176 ? 105.732 142.038 84.288  1.00 16.81  ? 176 GLN B CB  1 
ATOM   3149 C CG  . GLN B 2 176 ? 107.207 141.699 84.378  1.00 16.81  ? 176 GLN B CG  1 
ATOM   3150 C CD  . GLN B 2 176 ? 107.486 140.203 84.328  1.00 16.81  ? 176 GLN B CD  1 
ATOM   3151 O OE1 . GLN B 2 176 ? 108.642 139.787 84.316  1.00 16.81  ? 176 GLN B OE1 1 
ATOM   3152 N NE2 . GLN B 2 176 ? 106.434 139.388 84.295  1.00 16.81  ? 176 GLN B NE2 1 
ATOM   3153 N N   . THR B 2 177 ? 106.645 145.081 83.034  1.00 15.57  ? 177 THR B N   1 
ATOM   3154 C CA  . THR B 2 177 ? 106.863 145.921 81.864  1.00 15.57  ? 177 THR B CA  1 
ATOM   3155 C C   . THR B 2 177 ? 107.904 145.367 80.906  1.00 15.57  ? 177 THR B C   1 
ATOM   3156 O O   . THR B 2 177 ? 107.772 145.558 79.694  1.00 15.57  ? 177 THR B O   1 
ATOM   3157 C CB  . THR B 2 177 ? 107.283 147.328 82.301  1.00 15.57  ? 177 THR B CB  1 
ATOM   3158 O OG1 . THR B 2 177 ? 106.186 147.972 82.957  1.00 15.57  ? 177 THR B OG1 1 
ATOM   3159 C CG2 . THR B 2 177 ? 107.699 148.161 81.102  1.00 15.57  ? 177 THR B CG2 1 
ATOM   3160 N N   . THR B 2 178 ? 108.930 144.684 81.409  1.00 16.53  ? 178 THR B N   1 
ATOM   3161 C CA  . THR B 2 178 ? 109.959 144.118 80.551  1.00 16.53  ? 178 THR B CA  1 
ATOM   3162 C C   . THR B 2 178 ? 110.459 142.822 81.170  1.00 16.53  ? 178 THR B C   1 
ATOM   3163 O O   . THR B 2 178 ? 110.377 142.627 82.384  1.00 16.53  ? 178 THR B O   1 
ATOM   3164 C CB  . THR B 2 178 ? 111.127 145.090 80.350  1.00 16.53  ? 178 THR B CB  1 
ATOM   3165 O OG1 . THR B 2 178 ? 110.625 146.361 79.924  1.00 16.53  ? 178 THR B OG1 1 
ATOM   3166 C CG2 . THR B 2 178 ? 112.095 144.563 79.303  1.00 16.53  ? 178 THR B CG2 1 
ATOM   3167 N N   . THR B 2 179 ? 110.974 141.939 80.320  1.00 14.26  ? 179 THR B N   1 
ATOM   3168 C CA  . THR B 2 179 ? 111.519 140.659 80.750  1.00 14.26  ? 179 THR B CA  1 
ATOM   3169 C C   . THR B 2 179 ? 112.890 140.472 80.126  1.00 14.26  ? 179 THR B C   1 
ATOM   3170 O O   . THR B 2 179 ? 113.045 140.607 78.908  1.00 14.26  ? 179 THR B O   1 
ATOM   3171 C CB  . THR B 2 179 ? 110.599 139.502 80.353  1.00 14.26  ? 179 THR B CB  1 
ATOM   3172 O OG1 . THR B 2 179 ? 109.262 139.784 80.781  1.00 14.26  ? 179 THR B OG1 1 
ATOM   3173 C CG2 . THR B 2 179 ? 111.068 138.208 80.991  1.00 14.26  ? 179 THR B CG2 1 
ATOM   3174 N N   . PHE B 2 180 ? 113.879 140.163 80.957  1.00 16.39  ? 180 PHE B N   1 
ATOM   3175 C CA  . PHE B 2 180 ? 115.244 139.923 80.515  1.00 16.39  ? 180 PHE B CA  1 
ATOM   3176 C C   . PHE B 2 180 ? 115.526 138.429 80.575  1.00 16.39  ? 180 PHE B C   1 
ATOM   3177 O O   . PHE B 2 180 ? 115.283 137.791 81.604  1.00 16.39  ? 180 PHE B O   1 
ATOM   3178 C CB  . PHE B 2 180 ? 116.240 140.694 81.383  1.00 16.39  ? 180 PHE B CB  1 
ATOM   3179 C CG  . PHE B 2 180 ? 115.928 142.159 81.511  1.00 16.39  ? 180 PHE B CG  1 
ATOM   3180 C CD1 . PHE B 2 180 ? 116.398 143.065 80.580  1.00 16.39  ? 180 PHE B CD1 1 
ATOM   3181 C CD2 . PHE B 2 180 ? 115.170 142.628 82.564  1.00 16.39  ? 180 PHE B CD2 1 
ATOM   3182 C CE1 . PHE B 2 180 ? 116.112 144.407 80.700  1.00 16.39  ? 180 PHE B CE1 1 
ATOM   3183 C CE2 . PHE B 2 180 ? 114.883 143.969 82.685  1.00 16.39  ? 180 PHE B CE2 1 
ATOM   3184 C CZ  . PHE B 2 180 ? 115.354 144.857 81.752  1.00 16.39  ? 180 PHE B CZ  1 
ATOM   3185 N N   . THR B 2 181 ? 116.035 137.876 79.478  1.00 14.95  ? 181 THR B N   1 
ATOM   3186 C CA  . THR B 2 181 ? 116.250 136.440 79.363  1.00 14.95  ? 181 THR B CA  1 
ATOM   3187 C C   . THR B 2 181 ? 117.599 136.173 78.715  1.00 14.95  ? 181 THR B C   1 
ATOM   3188 O O   . THR B 2 181 ? 118.144 137.013 77.996  1.00 14.95  ? 181 THR B O   1 
ATOM   3189 C CB  . THR B 2 181 ? 115.143 135.770 78.543  1.00 14.95  ? 181 THR B CB  1 
ATOM   3190 O OG1 . THR B 2 181 ? 115.148 136.301 77.213  1.00 14.95  ? 181 THR B OG1 1 
ATOM   3191 C CG2 . THR B 2 181 ? 113.785 136.013 79.177  1.00 14.95  ? 181 THR B CG2 1 
ATOM   3192 N N   . GLY B 2 182 ? 118.127 134.978 78.969  1.00 16.07  ? 182 GLY B N   1 
ATOM   3193 C CA  . GLY B 2 182 ? 119.395 134.578 78.391  1.00 16.07  ? 182 GLY B CA  1 
ATOM   3194 C C   . GLY B 2 182 ? 120.246 133.711 79.296  1.00 16.07  ? 182 GLY B C   1 
ATOM   3195 O O   . GLY B 2 182 ? 121.151 133.020 78.820  1.00 16.07  ? 182 GLY B O   1 
ATOM   3196 N N   . HIS B 2 183 ? 119.976 133.734 80.596  1.00 15.24  ? 183 HIS B N   1 
ATOM   3197 C CA  . HIS B 2 183 ? 120.729 132.913 81.530  1.00 15.24  ? 183 HIS B CA  1 
ATOM   3198 C C   . HIS B 2 183 ? 120.244 131.470 81.488  1.00 15.24  ? 183 HIS B C   1 
ATOM   3199 O O   . HIS B 2 183 ? 119.094 131.188 81.140  1.00 15.24  ? 183 HIS B O   1 
ATOM   3200 C CB  . HIS B 2 183 ? 120.600 133.458 82.952  1.00 15.24  ? 183 HIS B CB  1 
ATOM   3201 C CG  . HIS B 2 183 ? 121.579 134.541 83.274  1.00 15.24  ? 183 HIS B CG  1 
ATOM   3202 N ND1 . HIS B 2 183 ? 122.943 134.355 83.209  1.00 15.24  ? 183 HIS B ND1 1 
ATOM   3203 C CD2 . HIS B 2 183 ? 121.392 135.824 83.662  1.00 15.24  ? 183 HIS B CD2 1 
ATOM   3204 C CE1 . HIS B 2 183 ? 123.554 135.476 83.544  1.00 15.24  ? 183 HIS B CE1 1 
ATOM   3205 N NE2 . HIS B 2 183 ? 122.636 136.383 83.822  1.00 15.24  ? 183 HIS B NE2 1 
ATOM   3206 N N   . THR B 2 184 ? 121.139 130.553 81.845  1.00 18.84  ? 184 THR B N   1 
ATOM   3207 C CA  . THR B 2 184 ? 120.819 129.135 81.933  1.00 18.84  ? 184 THR B CA  1 
ATOM   3208 C C   . THR B 2 184 ? 120.818 128.619 83.364  1.00 18.84  ? 184 THR B C   1 
ATOM   3209 O O   . THR B 2 184 ? 120.704 127.408 83.570  1.00 18.84  ? 184 THR B O   1 
ATOM   3210 C CB  . THR B 2 184 ? 121.808 128.315 81.096  1.00 18.84  ? 184 THR B CB  1 
ATOM   3211 O OG1 . THR B 2 184 ? 123.037 128.163 81.814  1.00 18.84  ? 184 THR B OG1 1 
ATOM   3212 C CG2 . THR B 2 184 ? 122.082 128.999 79.767  1.00 18.84  ? 184 THR B CG2 1 
ATOM   3213 N N   . GLY B 2 185 ? 120.946 129.501 84.355  1.00 19.54  ? 185 GLY B N   1 
ATOM   3214 C CA  . GLY B 2 185 ? 120.924 129.097 85.745  1.00 19.54  ? 185 GLY B CA  1 
ATOM   3215 C C   . GLY B 2 185 ? 120.297 130.183 86.591  1.00 19.54  ? 185 GLY B C   1 
ATOM   3216 O O   . GLY B 2 185 ? 120.077 131.306 86.133  1.00 19.54  ? 185 GLY B O   1 
ATOM   3217 N N   . ASP B 2 186 ? 120.009 129.833 87.842  1.00 15.73  ? 186 ASP B N   1 
ATOM   3218 C CA  . ASP B 2 186 ? 119.368 130.777 88.746  1.00 15.73  ? 186 ASP B CA  1 
ATOM   3219 C C   . ASP B 2 186 ? 120.199 132.045 88.862  1.00 15.73  ? 186 ASP B C   1 
ATOM   3220 O O   . ASP B 2 186 ? 121.425 131.993 88.981  1.00 15.73  ? 186 ASP B O   1 
ATOM   3221 C CB  . ASP B 2 186 ? 119.183 130.147 90.127  1.00 15.73  ? 186 ASP B CB  1 
ATOM   3222 C CG  . ASP B 2 186 ? 118.416 128.847 90.075  1.00 15.73  ? 186 ASP B CG  1 
ATOM   3223 O OD1 . ASP B 2 186 ? 117.959 128.468 88.978  1.00 15.73  ? 186 ASP B OD1 1 
ATOM   3224 O OD2 . ASP B 2 186 ? 118.270 128.202 91.135  1.00 15.73  ? 186 ASP B OD2 1 
ATOM   3225 N N   . VAL B 2 187 ? 119.525 133.189 88.823  1.00 13.15  ? 187 VAL B N   1 
ATOM   3226 C CA  . VAL B 2 187 ? 120.178 134.485 88.946  1.00 13.15  ? 187 VAL B CA  1 
ATOM   3227 C C   . VAL B 2 187 ? 120.274 134.812 90.431  1.00 13.15  ? 187 VAL B C   1 
ATOM   3228 O O   . VAL B 2 187 ? 119.256 134.984 91.105  1.00 13.15  ? 187 VAL B O   1 
ATOM   3229 C CB  . VAL B 2 187 ? 119.419 135.572 88.180  1.00 13.15  ? 187 VAL B CB  1 
ATOM   3230 C CG1 . VAL B 2 187 ? 120.153 136.892 88.276  1.00 13.15  ? 187 VAL B CG1 1 
ATOM   3231 C CG2 . VAL B 2 187 ? 119.240 135.159 86.730  1.00 13.15  ? 187 VAL B CG2 1 
ATOM   3232 N N   . MET B 2 188 ? 121.498 134.897 90.942  1.00 13.82  ? 188 MET B N   1 
ATOM   3233 C CA  . MET B 2 188 ? 121.722 135.013 92.375  1.00 13.82  ? 188 MET B CA  1 
ATOM   3234 C C   . MET B 2 188 ? 121.911 136.447 92.851  1.00 13.82  ? 188 MET B C   1 
ATOM   3235 O O   . MET B 2 188 ? 122.019 136.663 94.062  1.00 13.82  ? 188 MET B O   1 
ATOM   3236 C CB  . MET B 2 188 ? 122.952 134.190 92.776  1.00 13.82  ? 188 MET B CB  1 
ATOM   3237 C CG  . MET B 2 188 ? 122.785 132.679 92.642  1.00 13.82  ? 188 MET B CG  1 
ATOM   3238 S SD  . MET B 2 188 ? 121.250 132.022 93.326  1.00 13.82  ? 188 MET B SD  1 
ATOM   3239 C CE  . MET B 2 188 ? 121.562 132.165 95.081  1.00 13.82  ? 188 MET B CE  1 
ATOM   3240 N N   . SER B 2 189 ? 121.954 137.426 91.957  1.00 15.00  ? 189 SER B N   1 
ATOM   3241 C CA  . SER B 2 189 ? 122.157 138.814 92.364  1.00 15.00  ? 189 SER B CA  1 
ATOM   3242 C C   . SER B 2 189 ? 122.035 139.708 91.137  1.00 15.00  ? 189 SER B C   1 
ATOM   3243 O O   . SER B 2 189 ? 121.865 139.237 90.010  1.00 15.00  ? 189 SER B O   1 
ATOM   3244 C CB  . SER B 2 189 ? 123.513 138.996 93.042  1.00 15.00  ? 189 SER B CB  1 
ATOM   3245 O OG  . SER B 2 189 ? 124.562 138.594 92.182  1.00 15.00  ? 189 SER B OG  1 
ATOM   3246 N N   . LEU B 2 190 ? 122.118 141.015 91.375  1.00 17.11  ? 190 LEU B N   1 
ATOM   3247 C CA  . LEU B 2 190 ? 122.174 142.013 90.316  1.00 17.11  ? 190 LEU B CA  1 
ATOM   3248 C C   . LEU B 2 190 ? 122.724 143.297 90.922  1.00 17.11  ? 190 LEU B C   1 
ATOM   3249 O O   . LEU B 2 190 ? 122.971 143.376 92.127  1.00 17.11  ? 190 LEU B O   1 
ATOM   3250 C CB  . LEU B 2 190 ? 120.801 142.217 89.669  1.00 17.11  ? 190 LEU B CB  1 
ATOM   3251 C CG  . LEU B 2 190 ? 119.703 142.847 90.525  1.00 17.11  ? 190 LEU B CG  1 
ATOM   3252 C CD1 . LEU B 2 190 ? 119.637 144.347 90.321  1.00 17.11  ? 190 LEU B CD1 1 
ATOM   3253 C CD2 . LEU B 2 190 ? 118.371 142.213 90.198  1.00 17.11  ? 190 LEU B CD2 1 
ATOM   3254 N N   . SER B 2 191 ? 122.924 144.308 90.079  1.00 28.35  ? 191 SER B N   1 
ATOM   3255 C CA  . SER B 2 191 ? 123.521 145.558 90.548  1.00 28.35  ? 191 SER B CA  1 
ATOM   3256 C C   . SER B 2 191 ? 123.199 146.672 89.567  1.00 28.35  ? 191 SER B C   1 
ATOM   3257 O O   . SER B 2 191 ? 123.609 146.611 88.404  1.00 28.35  ? 191 SER B O   1 
ATOM   3258 C CB  . SER B 2 191 ? 125.031 145.404 90.708  1.00 28.35  ? 191 SER B CB  1 
ATOM   3259 O OG  . SER B 2 191 ? 125.585 146.519 91.378  1.00 28.35  ? 191 SER B OG  1 
ATOM   3260 N N   . LEU B 2 192 ? 122.479 147.687 90.032  1.00 18.60  ? 192 LEU B N   1 
ATOM   3261 C CA  . LEU B 2 192 ? 122.167 148.834 89.193  1.00 18.60  ? 192 LEU B CA  1 
ATOM   3262 C C   . LEU B 2 192 ? 123.410 149.678 88.950  1.00 18.60  ? 192 LEU B C   1 
ATOM   3263 O O   . LEU B 2 192 ? 124.275 149.817 89.816  1.00 18.60  ? 192 LEU B O   1 
ATOM   3264 C CB  . LEU B 2 192 ? 121.086 149.694 89.844  1.00 18.60  ? 192 LEU B CB  1 
ATOM   3265 C CG  . LEU B 2 192 ? 119.651 149.178 89.778  1.00 18.60  ? 192 LEU B CG  1 
ATOM   3266 C CD1 . LEU B 2 192 ? 118.760 150.025 90.665  1.00 18.60  ? 192 LEU B CD1 1 
ATOM   3267 C CD2 . LEU B 2 192 ? 119.144 149.176 88.346  1.00 18.60  ? 192 LEU B CD2 1 
ATOM   3268 N N   . ALA B 2 193 ? 123.493 150.252 87.753  1.00 22.31  ? 193 ALA B N   1 
ATOM   3269 C CA  . ALA B 2 193 ? 124.583 151.152 87.433  1.00 22.31  ? 193 ALA B CA  1 
ATOM   3270 C C   . ALA B 2 193 ? 124.429 152.468 88.191  1.00 22.31  ? 193 ALA B C   1 
ATOM   3271 O O   . ALA B 2 193 ? 123.328 152.829 88.614  1.00 22.31  ? 193 ALA B O   1 
ATOM   3272 C CB  . ALA B 2 193 ? 124.629 151.428 85.932  1.00 22.31  ? 193 ALA B CB  1 
ATOM   3273 N N   . PRO B 2 194 ? 125.526 153.209 88.372  1.00 18.77  ? 194 PRO B N   1 
ATOM   3274 C CA  . PRO B 2 194 ? 125.395 154.545 88.975  1.00 18.77  ? 194 PRO B CA  1 
ATOM   3275 C C   . PRO B 2 194 ? 124.432 155.440 88.220  1.00 18.77  ? 194 PRO B C   1 
ATOM   3276 O O   . PRO B 2 194 ? 123.667 156.185 88.844  1.00 18.77  ? 194 PRO B O   1 
ATOM   3277 C CB  . PRO B 2 194 ? 126.830 155.086 88.933  1.00 18.77  ? 194 PRO B CB  1 
ATOM   3278 C CG  . PRO B 2 194 ? 127.690 153.881 88.892  1.00 18.77  ? 194 PRO B CG  1 
ATOM   3279 C CD  . PRO B 2 194 ? 126.930 152.853 88.120  1.00 18.77  ? 194 PRO B CD  1 
ATOM   3280 N N   . ASP B 2 195 ? 124.435 155.376 86.889  1.00 22.97  ? 195 ASP B N   1 
ATOM   3281 C CA  . ASP B 2 195 ? 123.476 156.129 86.091  1.00 22.97  ? 195 ASP B CA  1 
ATOM   3282 C C   . ASP B 2 195 ? 122.142 155.411 85.956  1.00 22.97  ? 195 ASP B C   1 
ATOM   3283 O O   . ASP B 2 195 ? 121.215 155.965 85.356  1.00 22.97  ? 195 ASP B O   1 
ATOM   3284 C CB  . ASP B 2 195 ? 124.049 156.417 84.699  1.00 22.97  ? 195 ASP B CB  1 
ATOM   3285 C CG  . ASP B 2 195 ? 124.431 155.158 83.948  1.00 22.97  ? 195 ASP B CG  1 
ATOM   3286 O OD1 . ASP B 2 195 ? 123.843 154.092 84.223  1.00 22.97  ? 195 ASP B OD1 1 
ATOM   3287 O OD2 . ASP B 2 195 ? 125.317 155.235 83.071  1.00 22.97  ? 195 ASP B OD2 1 
ATOM   3288 N N   . THR B 2 196 ? 122.026 154.195 86.493  1.00 22.79  ? 196 THR B N   1 
ATOM   3289 C CA  . THR B 2 196 ? 120.772 153.444 86.488  1.00 22.79  ? 196 THR B CA  1 
ATOM   3290 C C   . THR B 2 196 ? 120.235 153.265 85.071  1.00 22.79  ? 196 THR B C   1 
ATOM   3291 O O   . THR B 2 196 ? 119.035 153.398 84.821  1.00 22.79  ? 196 THR B O   1 
ATOM   3292 C CB  . THR B 2 196 ? 119.726 154.113 87.381  1.00 22.79  ? 196 THR B CB  1 
ATOM   3293 O OG1 . THR B 2 196 ? 119.371 155.390 86.838  1.00 22.79  ? 196 THR B OG1 1 
ATOM   3294 C CG2 . THR B 2 196 ? 120.266 154.298 88.792  1.00 22.79  ? 196 THR B CG2 1 
ATOM   3295 N N   . ARG B 2 197 ? 121.131 152.963 84.132  1.00 22.59  ? 197 ARG B N   1 
ATOM   3296 C CA  . ARG B 2 197 ? 120.745 152.604 82.776  1.00 22.59  ? 197 ARG B CA  1 
ATOM   3297 C C   . ARG B 2 197 ? 121.257 151.238 82.347  1.00 22.59  ? 197 ARG B C   1 
ATOM   3298 O O   . ARG B 2 197 ? 120.810 150.729 81.314  1.00 22.59  ? 197 ARG B O   1 
ATOM   3299 C CB  . ARG B 2 197 ? 121.239 153.662 81.779  1.00 22.59  ? 197 ARG B CB  1 
ATOM   3300 C CG  . ARG B 2 197 ? 120.187 154.702 81.422  1.00 22.59  ? 197 ARG B CG  1 
ATOM   3301 C CD  . ARG B 2 197 ? 120.684 155.695 80.380  1.00 22.59  ? 197 ARG B CD  1 
ATOM   3302 N NE  . ARG B 2 197 ? 122.008 156.222 80.694  1.00 22.59  ? 197 ARG B NE  1 
ATOM   3303 C CZ  . ARG B 2 197 ? 123.150 155.729 80.234  1.00 22.59  ? 197 ARG B CZ  1 
ATOM   3304 N NH1 . ARG B 2 197 ? 123.179 154.681 79.426  1.00 22.59  ? 197 ARG B NH1 1 
ATOM   3305 N NH2 . ARG B 2 197 ? 124.295 156.301 80.595  1.00 22.59  ? 197 ARG B NH2 1 
ATOM   3306 N N   . LEU B 2 198 ? 122.176 150.638 83.100  1.00 23.32  ? 198 LEU B N   1 
ATOM   3307 C CA  . LEU B 2 198 ? 122.638 149.279 82.863  1.00 23.32  ? 198 LEU B CA  1 
ATOM   3308 C C   . LEU B 2 198 ? 122.690 148.538 84.189  1.00 23.32  ? 198 LEU B C   1 
ATOM   3309 O O   . LEU B 2 198 ? 122.801 149.144 85.257  1.00 23.32  ? 198 LEU B O   1 
ATOM   3310 C CB  . LEU B 2 198 ? 124.027 149.247 82.211  1.00 23.32  ? 198 LEU B CB  1 
ATOM   3311 C CG  . LEU B 2 198 ? 124.212 150.003 80.900  1.00 23.32  ? 198 LEU B CG  1 
ATOM   3312 C CD1 . LEU B 2 198 ? 125.678 150.017 80.517  1.00 23.32  ? 198 LEU B CD1 1 
ATOM   3313 C CD2 . LEU B 2 198 ? 123.383 149.374 79.804  1.00 23.32  ? 198 LEU B CD2 1 
ATOM   3314 N N   . PHE B 2 199 ? 122.608 147.212 84.116  1.00 17.56  ? 199 PHE B N   1 
ATOM   3315 C CA  . PHE B 2 199 ? 122.776 146.386 85.300  1.00 17.56  ? 199 PHE B CA  1 
ATOM   3316 C C   . PHE B 2 199 ? 123.262 145.011 84.878  1.00 17.56  ? 199 PHE B C   1 
ATOM   3317 O O   . PHE B 2 199 ? 123.124 144.612 83.720  1.00 17.56  ? 199 PHE B O   1 
ATOM   3318 C CB  . PHE B 2 199 ? 121.478 146.280 86.106  1.00 17.56  ? 199 PHE B CB  1 
ATOM   3319 C CG  . PHE B 2 199 ? 120.494 145.296 85.551  1.00 17.56  ? 199 PHE B CG  1 
ATOM   3320 C CD1 . PHE B 2 199 ? 119.699 145.625 84.472  1.00 17.56  ? 199 PHE B CD1 1 
ATOM   3321 C CD2 . PHE B 2 199 ? 120.353 144.046 86.120  1.00 17.56  ? 199 PHE B CD2 1 
ATOM   3322 C CE1 . PHE B 2 199 ? 118.789 144.723 83.970  1.00 17.56  ? 199 PHE B CE1 1 
ATOM   3323 C CE2 . PHE B 2 199 ? 119.446 143.142 85.619  1.00 17.56  ? 199 PHE B CE2 1 
ATOM   3324 C CZ  . PHE B 2 199 ? 118.664 143.481 84.543  1.00 17.56  ? 199 PHE B CZ  1 
ATOM   3325 N N   . VAL B 2 200 ? 123.840 144.289 85.835  1.00 15.82  ? 200 VAL B N   1 
ATOM   3326 C CA  . VAL B 2 200 ? 124.396 142.967 85.593  1.00 15.82  ? 200 VAL B CA  1 
ATOM   3327 C C   . VAL B 2 200 ? 123.650 141.960 86.455  1.00 15.82  ? 200 VAL B C   1 
ATOM   3328 O O   . VAL B 2 200 ? 122.815 142.309 87.288  1.00 15.82  ? 200 VAL B O   1 
ATOM   3329 C CB  . VAL B 2 200 ? 125.904 142.893 85.889  1.00 15.82  ? 200 VAL B CB  1 
ATOM   3330 C CG1 . VAL B 2 200 ? 126.689 143.719 84.888  1.00 15.82  ? 200 VAL B CG1 1 
ATOM   3331 C CG2 . VAL B 2 200 ? 126.179 143.307 87.319  1.00 15.82  ? 200 VAL B CG2 1 
ATOM   3332 N N   . SER B 2 201 ? 123.979 140.692 86.244  1.00 13.13  ? 201 SER B N   1 
ATOM   3333 C CA  . SER B 2 201 ? 123.408 139.605 87.017  1.00 13.13  ? 201 SER B CA  1 
ATOM   3334 C C   . SER B 2 201 ? 124.398 138.454 87.034  1.00 13.13  ? 201 SER B C   1 
ATOM   3335 O O   . SER B 2 201 ? 125.069 138.193 86.034  1.00 13.13  ? 201 SER B O   1 
ATOM   3336 C CB  . SER B 2 201 ? 122.075 139.155 86.423  1.00 13.13  ? 201 SER B CB  1 
ATOM   3337 O OG  . SER B 2 201 ? 122.171 139.067 85.013  1.00 13.13  ? 201 SER B OG  1 
ATOM   3338 N N   . GLY B 2 202 ? 124.490 137.780 88.175  1.00 14.42  ? 202 GLY B N   1 
ATOM   3339 C CA  . GLY B 2 202 ? 125.337 136.612 88.296  1.00 14.42  ? 202 GLY B CA  1 
ATOM   3340 C C   . GLY B 2 202 ? 124.516 135.349 88.432  1.00 14.42  ? 202 GLY B C   1 
ATOM   3341 O O   . GLY B 2 202 ? 123.785 135.182 89.410  1.00 14.42  ? 202 GLY B O   1 
ATOM   3342 N N   . ALA B 2 203 ? 124.626 134.454 87.459  1.00 14.70  ? 203 ALA B N   1 
ATOM   3343 C CA  . ALA B 2 203 ? 123.825 133.243 87.427  1.00 14.70  ? 203 ALA B CA  1 
ATOM   3344 C C   . ALA B 2 203 ? 124.647 132.046 87.882  1.00 14.70  ? 203 ALA B C   1 
ATOM   3345 O O   . ALA B 2 203 ? 125.867 132.117 88.042  1.00 14.70  ? 203 ALA B O   1 
ATOM   3346 C CB  . ALA B 2 203 ? 123.271 133.006 86.021  1.00 14.70  ? 203 ALA B CB  1 
ATOM   3347 N N   . CYS B 2 204 ? 123.957 130.928 88.086  1.00 15.39  ? 204 CYS B N   1 
ATOM   3348 C CA  . CYS B 2 204 ? 124.595 129.690 88.510  1.00 15.39  ? 204 CYS B CA  1 
ATOM   3349 C C   . CYS B 2 204 ? 125.225 128.923 87.356  1.00 15.39  ? 204 CYS B C   1 
ATOM   3350 O O   . CYS B 2 204 ? 125.548 127.744 87.521  1.00 15.39  ? 204 CYS B O   1 
ATOM   3351 C CB  . CYS B 2 204 ? 123.580 128.798 89.227  1.00 15.39  ? 204 CYS B CB  1 
ATOM   3352 S SG  . CYS B 2 204 ? 123.044 129.431 90.825  1.00 15.39  ? 204 CYS B SG  1 
ATOM   3353 N N   . ASP B 2 205 ? 125.399 129.555 86.197  1.00 16.61  ? 205 ASP B N   1 
ATOM   3354 C CA  . ASP B 2 205 ? 126.125 128.962 85.085  1.00 16.61  ? 205 ASP B CA  1 
ATOM   3355 C C   . ASP B 2 205 ? 127.553 129.478 84.978  1.00 16.61  ? 205 ASP B C   1 
ATOM   3356 O O   . ASP B 2 205 ? 128.243 129.154 84.007  1.00 16.61  ? 205 ASP B O   1 
ATOM   3357 C CB  . ASP B 2 205 ? 125.380 129.220 83.771  1.00 16.61  ? 205 ASP B CB  1 
ATOM   3358 C CG  . ASP B 2 205 ? 125.268 130.694 83.437  1.00 16.61  ? 205 ASP B CG  1 
ATOM   3359 O OD1 . ASP B 2 205 ? 125.929 131.516 84.101  1.00 16.61  ? 205 ASP B OD1 1 
ATOM   3360 O OD2 . ASP B 2 205 ? 124.520 131.034 82.498  1.00 16.61  ? 205 ASP B OD2 1 
ATOM   3361 N N   . ALA B 2 206 ? 128.009 130.271 85.950  1.00 14.49  ? 206 ALA B N   1 
ATOM   3362 C CA  . ALA B 2 206 ? 129.354 130.843 85.942  1.00 14.49  ? 206 ALA B CA  1 
ATOM   3363 C C   . ALA B 2 206 ? 129.528 131.824 84.780  1.00 14.49  ? 206 ALA B C   1 
ATOM   3364 O O   . ALA B 2 206 ? 130.499 131.758 84.028  1.00 14.49  ? 206 ALA B O   1 
ATOM   3365 C CB  . ALA B 2 206 ? 130.417 129.745 85.894  1.00 14.49  ? 206 ALA B CB  1 
ATOM   3366 N N   . SER B 2 207 ? 128.574 132.743 84.644  1.00 16.31  ? 207 SER B N   1 
ATOM   3367 C CA  . SER B 2 207 ? 128.623 133.752 83.596  1.00 16.31  ? 207 SER B CA  1 
ATOM   3368 C C   . SER B 2 207 ? 127.818 134.968 84.031  1.00 16.31  ? 207 SER B C   1 
ATOM   3369 O O   . SER B 2 207 ? 126.763 134.829 84.654  1.00 16.31  ? 207 SER B O   1 
ATOM   3370 C CB  . SER B 2 207 ? 128.076 133.211 82.272  1.00 16.31  ? 207 SER B CB  1 
ATOM   3371 O OG  . SER B 2 207 ? 126.684 132.975 82.363  1.00 16.31  ? 207 SER B OG  1 
ATOM   3372 N N   . ALA B 2 208 ? 128.322 136.152 83.695  1.00 19.83  ? 208 ALA B N   1 
ATOM   3373 C CA  . ALA B 2 208 ? 127.675 137.414 84.018  1.00 19.83  ? 208 ALA B CA  1 
ATOM   3374 C C   . ALA B 2 208 ? 127.301 138.135 82.732  1.00 19.83  ? 208 ALA B C   1 
ATOM   3375 O O   . ALA B 2 208 ? 128.093 138.185 81.787  1.00 19.83  ? 208 ALA B O   1 
ATOM   3376 C CB  . ALA B 2 208 ? 128.586 138.301 84.867  1.00 19.83  ? 208 ALA B CB  1 
ATOM   3377 N N   . LYS B 2 209 ? 126.095 138.697 82.704  1.00 17.68  ? 209 LYS B N   1 
ATOM   3378 C CA  . LYS B 2 209 ? 125.555 139.348 81.520  1.00 17.68  ? 209 LYS B CA  1 
ATOM   3379 C C   . LYS B 2 209 ? 125.241 140.806 81.820  1.00 17.68  ? 209 LYS B C   1 
ATOM   3380 O O   . LYS B 2 209 ? 124.885 141.163 82.944  1.00 17.68  ? 209 LYS B O   1 
ATOM   3381 C CB  . LYS B 2 209 ? 124.288 138.641 81.032  1.00 17.68  ? 209 LYS B CB  1 
ATOM   3382 C CG  . LYS B 2 209 ? 124.528 137.234 80.528  1.00 17.68  ? 209 LYS B CG  1 
ATOM   3383 C CD  . LYS B 2 209 ? 123.347 136.721 79.733  1.00 17.68  ? 209 LYS B CD  1 
ATOM   3384 C CE  . LYS B 2 209 ? 123.541 135.272 79.332  1.00 17.68  ? 209 LYS B CE  1 
ATOM   3385 N NZ  . LYS B 2 209 ? 124.716 135.090 78.438  1.00 17.68  ? 209 LYS B NZ  1 
ATOM   3386 N N   . LEU B 2 210 ? 125.372 141.643 80.795  1.00 18.67  ? 210 LEU B N   1 
ATOM   3387 C CA  . LEU B 2 210 ? 125.153 143.080 80.901  1.00 18.67  ? 210 LEU B CA  1 
ATOM   3388 C C   . LEU B 2 210 ? 123.919 143.444 80.088  1.00 18.67  ? 210 LEU B C   1 
ATOM   3389 O O   . LEU B 2 210 ? 123.844 143.127 78.897  1.00 18.67  ? 210 LEU B O   1 
ATOM   3390 C CB  . LEU B 2 210 ? 126.375 143.847 80.402  1.00 18.67  ? 210 LEU B CB  1 
ATOM   3391 C CG  . LEU B 2 210 ? 126.312 145.370 80.479  1.00 18.67  ? 210 LEU B CG  1 
ATOM   3392 C CD1 . LEU B 2 210 ? 126.294 145.829 81.922  1.00 18.67  ? 210 LEU B CD1 1 
ATOM   3393 C CD2 . LEU B 2 210 ? 127.487 145.975 79.735  1.00 18.67  ? 210 LEU B CD2 1 
ATOM   3394 N N   . TRP B 2 211 ? 122.966 144.116 80.726  1.00 17.15  ? 211 TRP B N   1 
ATOM   3395 C CA  . TRP B 2 211 ? 121.671 144.408 80.131  1.00 17.15  ? 211 TRP B CA  1 
ATOM   3396 C C   . TRP B 2 211 ? 121.497 145.902 79.899  1.00 17.15  ? 211 TRP B C   1 
ATOM   3397 O O   . TRP B 2 211 ? 122.143 146.738 80.534  1.00 17.15  ? 211 TRP B O   1 
ATOM   3398 C CB  . TRP B 2 211 ? 120.534 143.911 81.027  1.00 17.15  ? 211 TRP B CB  1 
ATOM   3399 C CG  . TRP B 2 211 ? 120.678 142.498 81.467  1.00 17.15  ? 211 TRP B CG  1 
ATOM   3400 C CD1 . TRP B 2 211 ? 121.301 142.052 82.591  1.00 17.15  ? 211 TRP B CD1 1 
ATOM   3401 C CD2 . TRP B 2 211 ? 120.176 141.339 80.798  1.00 17.15  ? 211 TRP B CD2 1 
ATOM   3402 N NE1 . TRP B 2 211 ? 121.223 140.685 82.664  1.00 17.15  ? 211 TRP B NE1 1 
ATOM   3403 C CE2 . TRP B 2 211 ? 120.536 140.222 81.573  1.00 17.15  ? 211 TRP B CE2 1 
ATOM   3404 C CE3 . TRP B 2 211 ? 119.458 141.136 79.619  1.00 17.15  ? 211 TRP B CE3 1 
ATOM   3405 C CZ2 . TRP B 2 211 ? 120.205 138.925 81.207  1.00 17.15  ? 211 TRP B CZ2 1 
ATOM   3406 C CZ3 . TRP B 2 211 ? 119.132 139.848 79.257  1.00 17.15  ? 211 TRP B CZ3 1 
ATOM   3407 C CH2 . TRP B 2 211 ? 119.505 138.759 80.048  1.00 17.15  ? 211 TRP B CH2 1 
ATOM   3408 N N   . ASP B 2 212 ? 120.602 146.225 78.971  1.00 25.47  ? 212 ASP B N   1 
ATOM   3409 C CA  . ASP B 2 212 ? 120.128 147.584 78.750  1.00 25.47  ? 212 ASP B CA  1 
ATOM   3410 C C   . ASP B 2 212 ? 118.704 147.665 79.279  1.00 25.47  ? 212 ASP B C   1 
ATOM   3411 O O   . ASP B 2 212 ? 117.839 146.894 78.855  1.00 25.47  ? 212 ASP B O   1 
ATOM   3412 C CB  . ASP B 2 212 ? 120.184 147.950 77.267  1.00 25.47  ? 212 ASP B CB  1 
ATOM   3413 C CG  . ASP B 2 212 ? 119.680 149.353 76.991  1.00 25.47  ? 212 ASP B CG  1 
ATOM   3414 O OD1 . ASP B 2 212 ? 118.527 149.659 77.357  1.00 25.47  ? 212 ASP B OD1 1 
ATOM   3415 O OD2 . ASP B 2 212 ? 120.440 150.150 76.404  1.00 25.47  ? 212 ASP B OD2 1 
ATOM   3416 N N   . VAL B 2 213 ? 118.462 148.598 80.201  1.00 22.76  ? 213 VAL B N   1 
ATOM   3417 C CA  . VAL B 2 213 ? 117.196 148.606 80.926  1.00 22.76  ? 213 VAL B CA  1 
ATOM   3418 C C   . VAL B 2 213 ? 116.032 148.900 79.987  1.00 22.76  ? 213 VAL B C   1 
ATOM   3419 O O   . VAL B 2 213 ? 114.933 148.360 80.157  1.00 22.76  ? 213 VAL B O   1 
ATOM   3420 C CB  . VAL B 2 213 ? 117.256 149.614 82.086  1.00 22.76  ? 213 VAL B CB  1 
ATOM   3421 C CG1 . VAL B 2 213 ? 115.854 150.007 82.527  1.00 22.76  ? 213 VAL B CG1 1 
ATOM   3422 C CG2 . VAL B 2 213 ? 118.040 149.034 83.249  1.00 22.76  ? 213 VAL B CG2 1 
ATOM   3423 N N   . ARG B 2 214 ? 116.243 149.759 78.990  1.00 26.57  ? 214 ARG B N   1 
ATOM   3424 C CA  . ARG B 2 214 ? 115.144 150.161 78.118  1.00 26.57  ? 214 ARG B CA  1 
ATOM   3425 C C   . ARG B 2 214 ? 114.874 149.117 77.040  1.00 26.57  ? 214 ARG B C   1 
ATOM   3426 O O   . ARG B 2 214 ? 113.770 148.571 76.950  1.00 26.57  ? 214 ARG B O   1 
ATOM   3427 C CB  . ARG B 2 214 ? 115.453 151.517 77.479  1.00 26.57  ? 214 ARG B CB  1 
ATOM   3428 N N   . GLU B 2 215 ? 115.881 148.827 76.212  1.00 37.04  ? 215 GLU B N   1 
ATOM   3429 C CA  . GLU B 2 215 ? 115.679 147.932 75.077  1.00 37.04  ? 215 GLU B CA  1 
ATOM   3430 C C   . GLU B 2 215 ? 115.390 146.505 75.515  1.00 37.04  ? 215 GLU B C   1 
ATOM   3431 O O   . GLU B 2 215 ? 114.704 145.765 74.802  1.00 37.04  ? 215 GLU B O   1 
ATOM   3432 C CB  . GLU B 2 215 ? 116.910 147.955 74.176  1.00 37.04  ? 215 GLU B CB  1 
ATOM   3433 C CG  . GLU B 2 215 ? 117.138 149.278 73.480  1.00 37.04  ? 215 GLU B CG  1 
ATOM   3434 C CD  . GLU B 2 215 ? 118.378 149.265 72.613  1.00 37.04  ? 215 GLU B CD  1 
ATOM   3435 O OE1 . GLU B 2 215 ? 119.123 148.264 72.661  1.00 37.04  ? 215 GLU B OE1 1 
ATOM   3436 O OE2 . GLU B 2 215 ? 118.608 150.255 71.888  1.00 37.04  ? 215 GLU B OE2 1 
ATOM   3437 N N   . GLY B 2 216 ? 115.904 146.097 76.669  1.00 30.64  ? 216 GLY B N   1 
ATOM   3438 C CA  . GLY B 2 216 ? 115.727 144.732 77.126  1.00 30.64  ? 216 GLY B CA  1 
ATOM   3439 C C   . GLY B 2 216 ? 116.445 143.696 76.291  1.00 30.64  ? 216 GLY B C   1 
ATOM   3440 O O   . GLY B 2 216 ? 115.872 142.640 75.997  1.00 30.64  ? 216 GLY B O   1 
ATOM   3441 N N   . MET B 2 217 ? 117.691 143.968 75.901  1.00 36.33  ? 217 MET B N   1 
ATOM   3442 C CA  . MET B 2 217 ? 118.524 142.994 75.211  1.00 36.33  ? 217 MET B CA  1 
ATOM   3443 C C   . MET B 2 217 ? 119.893 142.943 75.867  1.00 36.33  ? 217 MET B C   1 
ATOM   3444 O O   . MET B 2 217 ? 120.477 143.982 76.185  1.00 36.33  ? 217 MET B O   1 
ATOM   3445 C CB  . MET B 2 217 ? 118.693 143.327 73.724  1.00 36.33  ? 217 MET B CB  1 
ATOM   3446 C CG  . MET B 2 217 ? 119.437 144.624 73.448  1.00 36.33  ? 217 MET B CG  1 
ATOM   3447 S SD  . MET B 2 217 ? 119.517 145.005 71.688  1.00 36.33  ? 217 MET B SD  1 
ATOM   3448 C CE  . MET B 2 217 ? 117.833 145.509 71.351  1.00 36.33  ? 217 MET B CE  1 
ATOM   3449 N N   . CYS B 2 218 ? 120.405 141.731 76.058  1.00 28.82  ? 218 CYS B N   1 
ATOM   3450 C CA  . CYS B 2 218 ? 121.741 141.566 76.610  1.00 28.82  ? 218 CYS B CA  1 
ATOM   3451 C C   . CYS B 2 218 ? 122.780 142.118 75.642  1.00 28.82  ? 218 CYS B C   1 
ATOM   3452 O O   . CYS B 2 218 ? 122.631 142.035 74.421  1.00 28.82  ? 218 CYS B O   1 
ATOM   3453 C CB  . CYS B 2 218 ? 122.018 140.093 76.897  1.00 28.82  ? 218 CYS B CB  1 
ATOM   3454 S SG  . CYS B 2 218 ? 123.730 139.729 77.313  1.00 28.82  ? 218 CYS B SG  1 
ATOM   3455 N N   . ARG B 2 219 ? 123.846 142.691 76.200  1.00 27.05  ? 219 ARG B N   1 
ATOM   3456 C CA  . ARG B 2 219 ? 124.885 143.332 75.409  1.00 27.05  ? 219 ARG B CA  1 
ATOM   3457 C C   . ARG B 2 219 ? 126.198 142.569 75.383  1.00 27.05  ? 219 ARG B C   1 
ATOM   3458 O O   . ARG B 2 219 ? 126.882 142.585 74.359  1.00 27.05  ? 219 ARG B O   1 
ATOM   3459 C CB  . ARG B 2 219 ? 125.160 144.745 75.938  1.00 27.05  ? 219 ARG B CB  1 
ATOM   3460 C CG  . ARG B 2 219 ? 124.025 145.719 75.711  1.00 27.05  ? 219 ARG B CG  1 
ATOM   3461 C CD  . ARG B 2 219 ? 124.514 147.155 75.768  1.00 27.05  ? 219 ARG B CD  1 
ATOM   3462 N NE  . ARG B 2 219 ? 123.449 148.104 75.470  1.00 27.05  ? 219 ARG B NE  1 
ATOM   3463 C CZ  . ARG B 2 219 ? 122.902 148.269 74.274  1.00 27.05  ? 219 ARG B CZ  1 
ATOM   3464 N NH1 . ARG B 2 219 ? 123.303 147.566 73.226  1.00 27.05  ? 219 ARG B NH1 1 
ATOM   3465 N NH2 . ARG B 2 219 ? 121.927 149.161 74.123  1.00 27.05  ? 219 ARG B NH2 1 
ATOM   3466 N N   . GLN B 2 220 ? 126.573 141.913 76.477  1.00 29.60  ? 220 GLN B N   1 
ATOM   3467 C CA  . GLN B 2 220 ? 127.841 141.204 76.549  1.00 29.60  ? 220 GLN B CA  1 
ATOM   3468 C C   . GLN B 2 220 ? 127.681 139.989 77.448  1.00 29.60  ? 220 GLN B C   1 
ATOM   3469 O O   . GLN B 2 220 ? 126.620 139.755 78.030  1.00 29.60  ? 220 GLN B O   1 
ATOM   3470 C CB  . GLN B 2 220 ? 128.961 142.108 77.068  1.00 29.60  ? 220 GLN B CB  1 
ATOM   3471 C CG  . GLN B 2 220 ? 129.086 143.430 76.340  1.00 29.60  ? 220 GLN B CG  1 
ATOM   3472 C CD  . GLN B 2 220 ? 130.140 144.330 76.947  1.00 29.60  ? 220 GLN B CD  1 
ATOM   3473 O OE1 . GLN B 2 220 ? 129.864 145.474 77.305  1.00 29.60  ? 220 GLN B OE1 1 
ATOM   3474 N NE2 . GLN B 2 220 ? 131.357 143.815 77.068  1.00 29.60  ? 220 GLN B NE2 1 
ATOM   3475 N N   . THR B 2 221 ? 128.753 139.212 77.551  1.00 24.70  ? 221 THR B N   1 
ATOM   3476 C CA  . THR B 2 221 ? 128.773 138.034 78.412  1.00 24.70  ? 221 THR B CA  1 
ATOM   3477 C C   . THR B 2 221 ? 130.214 137.772 78.812  1.00 24.70  ? 221 THR B C   1 
ATOM   3478 O O   . THR B 2 221 ? 131.082 137.623 77.946  1.00 24.70  ? 221 THR B O   1 
ATOM   3479 C CB  . THR B 2 221 ? 128.177 136.816 77.704  1.00 24.70  ? 221 THR B CB  1 
ATOM   3480 O OG1 . THR B 2 221 ? 126.902 137.159 77.150  1.00 24.70  ? 221 THR B OG1 1 
ATOM   3481 C CG2 . THR B 2 221 ? 128.007 135.661 78.677  1.00 24.70  ? 221 THR B CG2 1 
ATOM   3482 N N   . PHE B 2 222 ? 130.464 137.718 80.115  1.00 22.16  ? 222 PHE B N   1 
ATOM   3483 C CA  . PHE B 2 222 ? 131.805 137.562 80.660  1.00 22.16  ? 222 PHE B CA  1 
ATOM   3484 C C   . PHE B 2 222 ? 131.924 136.192 81.310  1.00 22.16  ? 222 PHE B C   1 
ATOM   3485 O O   . PHE B 2 222 ? 131.055 135.795 82.092  1.00 22.16  ? 222 PHE B O   1 
ATOM   3486 C CB  . PHE B 2 222 ? 132.108 138.663 81.675  1.00 22.16  ? 222 PHE B CB  1 
ATOM   3487 C CG  . PHE B 2 222 ? 131.799 140.048 81.178  1.00 22.16  ? 222 PHE B CG  1 
ATOM   3488 C CD1 . PHE B 2 222 ? 130.526 140.573 81.297  1.00 22.16  ? 222 PHE B CD1 1 
ATOM   3489 C CD2 . PHE B 2 222 ? 132.781 140.824 80.594  1.00 22.16  ? 222 PHE B CD2 1 
ATOM   3490 C CE1 . PHE B 2 222 ? 130.241 141.842 80.843  1.00 22.16  ? 222 PHE B CE1 1 
ATOM   3491 C CE2 . PHE B 2 222 ? 132.499 142.093 80.138  1.00 22.16  ? 222 PHE B CE2 1 
ATOM   3492 C CZ  . PHE B 2 222 ? 131.228 142.602 80.263  1.00 22.16  ? 222 PHE B CZ  1 
ATOM   3493 N N   . THR B 2 223 ? 132.999 135.476 80.986  1.00 23.20  ? 223 THR B N   1 
ATOM   3494 C CA  . THR B 2 223 ? 133.227 134.129 81.486  1.00 23.20  ? 223 THR B CA  1 
ATOM   3495 C C   . THR B 2 223 ? 134.642 134.016 82.034  1.00 23.20  ? 223 THR B C   1 
ATOM   3496 O O   . THR B 2 223 ? 135.514 134.838 81.745  1.00 23.20  ? 223 THR B O   1 
ATOM   3497 C CB  . THR B 2 223 ? 133.015 133.079 80.390  1.00 23.20  ? 223 THR B CB  1 
ATOM   3498 O OG1 . THR B 2 223 ? 133.868 133.368 79.276  1.00 23.20  ? 223 THR B OG1 1 
ATOM   3499 C CG2 . THR B 2 223 ? 131.567 133.070 79.931  1.00 23.20  ? 223 THR B CG2 1 
ATOM   3500 N N   . GLY B 2 224 ? 134.863 132.969 82.826  1.00 18.60  ? 224 GLY B N   1 
ATOM   3501 C CA  . GLY B 2 224 ? 136.157 132.739 83.437  1.00 18.60  ? 224 GLY B CA  1 
ATOM   3502 C C   . GLY B 2 224 ? 136.068 132.103 84.808  1.00 18.60  ? 224 GLY B C   1 
ATOM   3503 O O   . GLY B 2 224 ? 137.042 131.516 85.285  1.00 18.60  ? 224 GLY B O   1 
ATOM   3504 N N   . HIS B 2 225 ? 134.910 132.207 85.452  1.00 14.55  ? 225 HIS B N   1 
ATOM   3505 C CA  . HIS B 2 225 ? 134.717 131.552 86.737  1.00 14.55  ? 225 HIS B CA  1 
ATOM   3506 C C   . HIS B 2 225 ? 134.500 130.057 86.543  1.00 14.55  ? 225 HIS B C   1 
ATOM   3507 O O   . HIS B 2 225 ? 134.015 129.614 85.499  1.00 14.55  ? 225 HIS B O   1 
ATOM   3508 C CB  . HIS B 2 225 ? 133.527 132.166 87.473  1.00 14.55  ? 225 HIS B CB  1 
ATOM   3509 C CG  . HIS B 2 225 ? 133.891 133.317 88.359  1.00 14.55  ? 225 HIS B CG  1 
ATOM   3510 N ND1 . HIS B 2 225 ? 134.747 133.189 89.429  1.00 14.55  ? 225 HIS B ND1 1 
ATOM   3511 C CD2 . HIS B 2 225 ? 133.510 134.616 88.335  1.00 14.55  ? 225 HIS B CD2 1 
ATOM   3512 C CE1 . HIS B 2 225 ? 134.880 134.359 90.028  1.00 14.55  ? 225 HIS B CE1 1 
ATOM   3513 N NE2 . HIS B 2 225 ? 134.141 135.242 89.382  1.00 14.55  ? 225 HIS B NE2 1 
ATOM   3514 N N   . GLU B 2 226 ? 134.863 129.275 87.563  1.00 14.40  ? 226 GLU B N   1 
ATOM   3515 C CA  . GLU B 2 226 ? 134.748 127.825 87.481  1.00 14.40  ? 226 GLU B CA  1 
ATOM   3516 C C   . GLU B 2 226 ? 133.399 127.314 87.964  1.00 14.40  ? 226 GLU B C   1 
ATOM   3517 O O   . GLU B 2 226 ? 132.972 126.240 87.530  1.00 14.40  ? 226 GLU B O   1 
ATOM   3518 C CB  . GLU B 2 226 ? 135.847 127.143 88.303  1.00 14.40  ? 226 GLU B CB  1 
ATOM   3519 C CG  . GLU B 2 226 ? 137.220 127.804 88.246  1.00 14.40  ? 226 GLU B CG  1 
ATOM   3520 C CD  . GLU B 2 226 ? 138.027 127.371 87.043  1.00 14.40  ? 226 GLU B CD  1 
ATOM   3521 O OE1 . GLU B 2 226 ? 137.424 126.887 86.066  1.00 14.40  ? 226 GLU B OE1 1 
ATOM   3522 O OE2 . GLU B 2 226 ? 139.268 127.510 87.076  1.00 14.40  ? 226 GLU B OE2 1 
ATOM   3523 N N   . SER B 2 227 ? 132.725 128.045 88.847  1.00 12.43  ? 227 SER B N   1 
ATOM   3524 C CA  . SER B 2 227 ? 131.495 127.568 89.460  1.00 12.43  ? 227 SER B CA  1 
ATOM   3525 C C   . SER B 2 227 ? 130.527 128.735 89.597  1.00 12.43  ? 227 SER B C   1 
ATOM   3526 O O   . SER B 2 227 ? 130.727 129.807 89.019  1.00 12.43  ? 227 SER B O   1 
ATOM   3527 C CB  . SER B 2 227 ? 131.781 126.915 90.814  1.00 12.43  ? 227 SER B CB  1 
ATOM   3528 O OG  . SER B 2 227 ? 130.645 126.218 91.291  1.00 12.43  ? 227 SER B OG  1 
ATOM   3529 N N   . ASP B 2 228 ? 129.469 128.516 90.378  1.00 12.81  ? 228 ASP B N   1 
ATOM   3530 C CA  . ASP B 2 228 ? 128.399 129.498 90.507  1.00 12.81  ? 228 ASP B CA  1 
ATOM   3531 C C   . ASP B 2 228 ? 128.949 130.857 90.914  1.00 12.81  ? 228 ASP B C   1 
ATOM   3532 O O   . ASP B 2 228 ? 130.060 130.962 91.439  1.00 12.81  ? 228 ASP B O   1 
ATOM   3533 C CB  . ASP B 2 228 ? 127.375 129.029 91.542  1.00 12.81  ? 228 ASP B CB  1 
ATOM   3534 C CG  . ASP B 2 228 ? 126.905 127.616 91.297  1.00 12.81  ? 228 ASP B CG  1 
ATOM   3535 O OD1 . ASP B 2 228 ? 127.141 127.096 90.188  1.00 12.81  ? 228 ASP B OD1 1 
ATOM   3536 O OD2 . ASP B 2 228 ? 126.305 127.022 92.215  1.00 12.81  ? 228 ASP B OD2 1 
ATOM   3537 N N   . ILE B 2 229 ? 128.164 131.899 90.660  1.00 12.15  ? 229 ILE B N   1 
ATOM   3538 C CA  . ILE B 2 229 ? 128.477 133.255 91.092  1.00 12.15  ? 229 ILE B CA  1 
ATOM   3539 C C   . ILE B 2 229 ? 127.415 133.677 92.096  1.00 12.15  ? 229 ILE B C   1 
ATOM   3540 O O   . ILE B 2 229 ? 126.216 133.640 91.795  1.00 12.15  ? 229 ILE B O   1 
ATOM   3541 C CB  . ILE B 2 229 ? 128.537 134.227 89.905  1.00 12.15  ? 229 ILE B CB  1 
ATOM   3542 C CG1 . ILE B 2 229 ? 129.720 133.883 89.003  1.00 12.15  ? 229 ILE B CG1 1 
ATOM   3543 C CG2 . ILE B 2 229 ? 128.652 135.656 90.394  1.00 12.15  ? 229 ILE B CG2 1 
ATOM   3544 C CD1 . ILE B 2 229 ? 129.619 134.467 87.620  1.00 12.15  ? 229 ILE B CD1 1 
ATOM   3545 N N   . ASN B 2 230 ? 127.850 134.078 93.290  1.00 11.60  ? 230 ASN B N   1 
ATOM   3546 C CA  . ASN B 2 230 ? 126.920 134.371 94.373  1.00 11.60  ? 230 ASN B CA  1 
ATOM   3547 C C   . ASN B 2 230 ? 126.653 135.858 94.547  1.00 11.60  ? 230 ASN B C   1 
ATOM   3548 O O   . ASN B 2 230 ? 125.590 136.228 95.056  1.00 11.60  ? 230 ASN B O   1 
ATOM   3549 C CB  . ASN B 2 230 ? 127.452 133.808 95.691  1.00 11.60  ? 230 ASN B CB  1 
ATOM   3550 C CG  . ASN B 2 230 ? 127.822 132.346 95.593  1.00 11.60  ? 230 ASN B CG  1 
ATOM   3551 O OD1 . ASN B 2 230 ? 126.952 131.477 95.556  1.00 11.60  ? 230 ASN B OD1 1 
ATOM   3552 N ND2 . ASN B 2 230 ? 129.117 132.065 95.559  1.00 11.60  ? 230 ASN B ND2 1 
ATOM   3553 N N   . ALA B 2 231 ? 127.585 136.719 94.149  1.00 17.48  ? 231 ALA B N   1 
ATOM   3554 C CA  . ALA B 2 231 ? 127.446 138.146 94.392  1.00 17.48  ? 231 ALA B CA  1 
ATOM   3555 C C   . ALA B 2 231 ? 128.150 138.923 93.292  1.00 17.48  ? 231 ALA B C   1 
ATOM   3556 O O   . ALA B 2 231 ? 129.028 138.403 92.600  1.00 17.48  ? 231 ALA B O   1 
ATOM   3557 C CB  . ALA B 2 231 ? 128.015 138.531 95.757  1.00 17.48  ? 231 ALA B CB  1 
ATOM   3558 N N   . ILE B 2 232 ? 127.757 140.188 93.146  1.00 18.85  ? 232 ILE B N   1 
ATOM   3559 C CA  . ILE B 2 232 ? 128.286 141.050 92.096  1.00 18.85  ? 232 ILE B CA  1 
ATOM   3560 C C   . ILE B 2 232 ? 128.097 142.495 92.535  1.00 18.85  ? 232 ILE B C   1 
ATOM   3561 O O   . ILE B 2 232 ? 127.247 142.796 93.370  1.00 18.85  ? 232 ILE B O   1 
ATOM   3562 C CB  . ILE B 2 232 ? 127.585 140.757 90.746  1.00 18.85  ? 232 ILE B CB  1 
ATOM   3563 C CG1 . ILE B 2 232 ? 128.281 141.494 89.604  1.00 18.85  ? 232 ILE B CG1 1 
ATOM   3564 C CG2 . ILE B 2 232 ? 126.121 141.138 90.819  1.00 18.85  ? 232 ILE B CG2 1 
ATOM   3565 C CD1 . ILE B 2 232 ? 128.020 140.889 88.249  1.00 18.85  ? 232 ILE B CD1 1 
ATOM   3566 N N   . CYS B 2 233 ? 128.906 143.394 91.977  1.00 33.26  ? 233 CYS B N   1 
ATOM   3567 C CA  . CYS B 2 233 ? 128.829 144.805 92.332  1.00 33.26  ? 233 CYS B CA  1 
ATOM   3568 C C   . CYS B 2 233 ? 129.695 145.614 91.375  1.00 33.26  ? 233 CYS B C   1 
ATOM   3569 O O   . CYS B 2 233 ? 130.816 145.210 91.068  1.00 33.26  ? 233 CYS B O   1 
ATOM   3570 C CB  . CYS B 2 233 ? 129.288 145.028 93.777  1.00 33.26  ? 233 CYS B CB  1 
ATOM   3571 S SG  . CYS B 2 233 ? 129.111 146.724 94.367  1.00 33.26  ? 233 CYS B SG  1 
ATOM   3572 N N   . PHE B 2 234 ? 129.197 146.802 91.014  1.00 19.75  ? 234 PHE B N   1 
ATOM   3573 C CA  . PHE B 2 234 ? 129.866 147.664 90.009  1.00 19.75  ? 234 PHE B CA  1 
ATOM   3574 C C   . PHE B 2 234 ? 130.898 148.616 90.598  1.00 19.75  ? 234 PHE B C   1 
ATOM   3575 O O   . PHE B 2 234 ? 130.571 149.312 91.572  1.00 19.75  ? 234 PHE B O   1 
ATOM   3576 C CB  . PHE B 2 234 ? 128.823 148.585 89.377  1.00 19.75  ? 234 PHE B CB  1 
ATOM   3577 C CG  . PHE B 2 234 ? 128.496 148.337 87.927  1.00 19.75  ? 234 PHE B CG  1 
ATOM   3578 C CD1 . PHE B 2 234 ? 129.387 148.690 86.928  1.00 19.75  ? 234 PHE B CD1 1 
ATOM   3579 C CD2 . PHE B 2 234 ? 127.282 147.780 87.561  1.00 19.75  ? 234 PHE B CD2 1 
ATOM   3580 C CE1 . PHE B 2 234 ? 129.079 148.472 85.596  1.00 19.75  ? 234 PHE B CE1 1 
ATOM   3581 C CE2 . PHE B 2 234 ? 126.975 147.563 86.228  1.00 19.75  ? 234 PHE B CE2 1 
ATOM   3582 C CZ  . PHE B 2 234 ? 127.874 147.911 85.248  1.00 19.75  ? 234 PHE B CZ  1 
ATOM   3583 N N   . PHE B 2 235 ? 132.090 148.681 89.997  1.00 21.62  ? 235 PHE B N   1 
ATOM   3584 C CA  . PHE B 2 235 ? 133.081 149.655 90.409  1.00 21.62  ? 235 PHE B CA  1 
ATOM   3585 C C   . PHE B 2 235 ? 132.409 151.024 90.549  1.00 21.62  ? 235 PHE B C   1 
ATOM   3586 O O   . PHE B 2 235 ? 131.423 151.308 89.861  1.00 21.62  ? 235 PHE B O   1 
ATOM   3587 C CB  . PHE B 2 235 ? 134.196 149.704 89.366  1.00 21.62  ? 235 PHE B CB  1 
ATOM   3588 C CG  . PHE B 2 235 ? 135.475 150.310 89.850  1.00 21.62  ? 235 PHE B CG  1 
ATOM   3589 C CD1 . PHE B 2 235 ? 136.402 149.541 90.521  1.00 21.62  ? 235 PHE B CD1 1 
ATOM   3590 C CD2 . PHE B 2 235 ? 135.771 151.635 89.598  1.00 21.62  ? 235 PHE B CD2 1 
ATOM   3591 C CE1 . PHE B 2 235 ? 137.587 150.087 90.957  1.00 21.62  ? 235 PHE B CE1 1 
ATOM   3592 C CE2 . PHE B 2 235 ? 136.955 152.185 90.035  1.00 21.62  ? 235 PHE B CE2 1 
ATOM   3593 C CZ  . PHE B 2 235 ? 137.864 151.409 90.713  1.00 21.62  ? 235 PHE B CZ  1 
ATOM   3594 N N   . PRO B 2 236 ? 132.905 151.890 91.439  1.00 22.52  ? 236 PRO B N   1 
ATOM   3595 C CA  . PRO B 2 236 ? 132.238 153.191 91.614  1.00 22.52  ? 236 PRO B CA  1 
ATOM   3596 C C   . PRO B 2 236 ? 132.092 153.984 90.328  1.00 22.52  ? 236 PRO B C   1 
ATOM   3597 O O   . PRO B 2 236 ? 131.072 154.657 90.140  1.00 22.52  ? 236 PRO B O   1 
ATOM   3598 C CB  . PRO B 2 236 ? 133.144 153.905 92.624  1.00 22.52  ? 236 PRO B CB  1 
ATOM   3599 C CG  . PRO B 2 236 ? 133.735 152.806 93.418  1.00 22.52  ? 236 PRO B CG  1 
ATOM   3600 C CD  . PRO B 2 236 ? 133.943 151.671 92.462  1.00 22.52  ? 236 PRO B CD  1 
ATOM   3601 N N   . ASN B 2 237 ? 133.076 153.930 89.431  1.00 20.63  ? 237 ASN B N   1 
ATOM   3602 C CA  . ASN B 2 237 ? 133.019 154.729 88.213  1.00 20.63  ? 237 ASN B CA  1 
ATOM   3603 C C   . ASN B 2 237 ? 132.140 154.109 87.135  1.00 20.63  ? 237 ASN B C   1 
ATOM   3604 O O   . ASN B 2 237 ? 131.870 154.772 86.129  1.00 20.63  ? 237 ASN B O   1 
ATOM   3605 C CB  . ASN B 2 237 ? 134.432 154.957 87.665  1.00 20.63  ? 237 ASN B CB  1 
ATOM   3606 C CG  . ASN B 2 237 ? 134.963 153.771 86.892  1.00 20.63  ? 237 ASN B CG  1 
ATOM   3607 O OD1 . ASN B 2 237 ? 134.461 152.656 87.013  1.00 20.63  ? 237 ASN B OD1 1 
ATOM   3608 N ND2 . ASN B 2 237 ? 135.987 154.009 86.085  1.00 20.63  ? 237 ASN B ND2 1 
ATOM   3609 N N   . GLY B 2 238 ? 131.692 152.870 87.316  1.00 18.81  ? 238 GLY B N   1 
ATOM   3610 C CA  . GLY B 2 238 ? 130.752 152.273 86.388  1.00 18.81  ? 238 GLY B CA  1 
ATOM   3611 C C   . GLY B 2 238 ? 131.350 151.757 85.099  1.00 18.81  ? 238 GLY B C   1 
ATOM   3612 O O   . GLY B 2 238 ? 130.655 151.717 84.081  1.00 18.81  ? 238 GLY B O   1 
ATOM   3613 N N   . ASN B 2 239 ? 132.623 151.359 85.107  1.00 21.63  ? 239 ASN B N   1 
ATOM   3614 C CA  . ASN B 2 239 ? 133.269 150.802 83.924  1.00 21.63  ? 239 ASN B CA  1 
ATOM   3615 C C   . ASN B 2 239 ? 133.983 149.496 84.252  1.00 21.63  ? 239 ASN B C   1 
ATOM   3616 O O   . ASN B 2 239 ? 134.982 149.150 83.619  1.00 21.63  ? 239 ASN B O   1 
ATOM   3617 C CB  . ASN B 2 239 ? 134.246 151.804 83.314  1.00 21.63  ? 239 ASN B CB  1 
ATOM   3618 C CG  . ASN B 2 239 ? 133.544 152.924 82.581  1.00 21.63  ? 239 ASN B CG  1 
ATOM   3619 O OD1 . ASN B 2 239 ? 132.351 152.843 82.296  1.00 21.63  ? 239 ASN B OD1 1 
ATOM   3620 N ND2 . ASN B 2 239 ? 134.286 153.980 82.264  1.00 21.63  ? 239 ASN B ND2 1 
ATOM   3621 N N   . ALA B 2 240 ? 133.480 148.765 85.242  1.00 23.14  ? 240 ALA B N   1 
ATOM   3622 C CA  . ALA B 2 240 ? 134.024 147.472 85.639  1.00 23.14  ? 240 ALA B CA  1 
ATOM   3623 C C   . ALA B 2 240 ? 133.143 146.954 86.765  1.00 23.14  ? 240 ALA B C   1 
ATOM   3624 O O   . ALA B 2 240 ? 132.243 147.651 87.242  1.00 23.14  ? 240 ALA B O   1 
ATOM   3625 C CB  . ALA B 2 240 ? 135.483 147.569 86.083  1.00 23.14  ? 240 ALA B CB  1 
ATOM   3626 N N   . PHE B 2 241 ? 133.402 145.720 87.183  1.00 18.26  ? 241 PHE B N   1 
ATOM   3627 C CA  . PHE B 2 241 ? 132.707 145.157 88.332  1.00 18.26  ? 241 PHE B CA  1 
ATOM   3628 C C   . PHE B 2 241 ? 133.462 143.922 88.798  1.00 18.26  ? 241 PHE B C   1 
ATOM   3629 O O   . PHE B 2 241 ? 134.447 143.504 88.184  1.00 18.26  ? 241 PHE B O   1 
ATOM   3630 C CB  . PHE B 2 241 ? 131.250 144.839 88.000  1.00 18.26  ? 241 PHE B CB  1 
ATOM   3631 C CG  . PHE B 2 241 ? 131.073 143.903 86.847  1.00 18.26  ? 241 PHE B CG  1 
ATOM   3632 C CD1 . PHE B 2 241 ? 131.011 142.540 87.052  1.00 18.26  ? 241 PHE B CD1 1 
ATOM   3633 C CD2 . PHE B 2 241 ? 130.942 144.386 85.562  1.00 18.26  ? 241 PHE B CD2 1 
ATOM   3634 C CE1 . PHE B 2 241 ? 130.836 141.678 85.996  1.00 18.26  ? 241 PHE B CE1 1 
ATOM   3635 C CE2 . PHE B 2 241 ? 130.767 143.528 84.503  1.00 18.26  ? 241 PHE B CE2 1 
ATOM   3636 C CZ  . PHE B 2 241 ? 130.715 142.174 84.720  1.00 18.26  ? 241 PHE B CZ  1 
ATOM   3637 N N   . ALA B 2 242 ? 132.995 143.346 89.900  1.00 28.35  ? 242 ALA B N   1 
ATOM   3638 C CA  . ALA B 2 242 ? 133.613 142.180 90.504  1.00 28.35  ? 242 ALA B CA  1 
ATOM   3639 C C   . ALA B 2 242 ? 132.534 141.175 90.868  1.00 28.35  ? 242 ALA B C   1 
ATOM   3640 O O   . ALA B 2 242 ? 131.349 141.503 90.932  1.00 28.35  ? 242 ALA B O   1 
ATOM   3641 C CB  . ALA B 2 242 ? 134.422 142.555 91.748  1.00 28.35  ? 242 ALA B CB  1 
ATOM   3642 N N   . THR B 2 243 ? 132.956 139.935 91.102  1.00 17.31  ? 243 THR B N   1 
ATOM   3643 C CA  . THR B 2 243 ? 132.022 138.857 91.382  1.00 17.31  ? 243 THR B CA  1 
ATOM   3644 C C   . THR B 2 243 ? 132.663 137.864 92.334  1.00 17.31  ? 243 THR B C   1 
ATOM   3645 O O   . THR B 2 243 ? 133.889 137.747 92.399  1.00 17.31  ? 243 THR B O   1 
ATOM   3646 C CB  . THR B 2 243 ? 131.597 138.134 90.101  1.00 17.31  ? 243 THR B CB  1 
ATOM   3647 O OG1 . THR B 2 243 ? 132.762 137.772 89.348  1.00 17.31  ? 243 THR B OG1 1 
ATOM   3648 C CG2 . THR B 2 243 ? 130.701 139.020 89.254  1.00 17.31  ? 243 THR B CG2 1 
ATOM   3649 N N   . GLY B 2 244 ? 131.819 137.147 93.070  1.00 13.75  ? 244 GLY B N   1 
ATOM   3650 C CA  . GLY B 2 244 ? 132.280 136.087 93.943  1.00 13.75  ? 244 GLY B CA  1 
ATOM   3651 C C   . GLY B 2 244 ? 131.730 134.748 93.507  1.00 13.75  ? 244 GLY B C   1 
ATOM   3652 O O   . GLY B 2 244 ? 130.549 134.643 93.168  1.00 13.75  ? 244 GLY B O   1 
ATOM   3653 N N   . SER B 2 245 ? 132.568 133.716 93.511  1.00 11.39  ? 245 SER B N   1 
ATOM   3654 C CA  . SER B 2 245 ? 132.187 132.405 93.013  1.00 11.39  ? 245 SER B CA  1 
ATOM   3655 C C   . SER B 2 245 ? 132.581 131.331 94.015  1.00 11.39  ? 245 SER B C   1 
ATOM   3656 O O   . SER B 2 245 ? 133.469 131.530 94.847  1.00 11.39  ? 245 SER B O   1 
ATOM   3657 C CB  . SER B 2 245 ? 132.839 132.123 91.656  1.00 11.39  ? 245 SER B CB  1 
ATOM   3658 O OG  . SER B 2 245 ? 132.323 130.940 91.075  1.00 11.39  ? 245 SER B OG  1 
ATOM   3659 N N   . ASP B 2 246 ? 131.905 130.184 93.925  1.00 11.42  ? 246 ASP B N   1 
ATOM   3660 C CA  . ASP B 2 246 ? 132.174 129.075 94.834  1.00 11.42  ? 246 ASP B CA  1 
ATOM   3661 C C   . ASP B 2 246 ? 133.559 128.472 94.642  1.00 11.42  ? 246 ASP B C   1 
ATOM   3662 O O   . ASP B 2 246 ? 133.999 127.696 95.496  1.00 11.42  ? 246 ASP B O   1 
ATOM   3663 C CB  . ASP B 2 246 ? 131.120 127.984 94.660  1.00 11.42  ? 246 ASP B CB  1 
ATOM   3664 C CG  . ASP B 2 246 ? 129.831 128.307 95.375  1.00 11.42  ? 246 ASP B CG  1 
ATOM   3665 O OD1 . ASP B 2 246 ? 129.714 129.431 95.905  1.00 11.42  ? 246 ASP B OD1 1 
ATOM   3666 O OD2 . ASP B 2 246 ? 128.936 127.437 95.414  1.00 11.42  ? 246 ASP B OD2 1 
ATOM   3667 N N   . ASP B 2 247 ? 134.251 128.796 93.553  1.00 11.79  ? 247 ASP B N   1 
ATOM   3668 C CA  . ASP B 2 247 ? 135.616 128.321 93.375  1.00 11.79  ? 247 ASP B CA  1 
ATOM   3669 C C   . ASP B 2 247 ? 136.609 129.035 94.280  1.00 11.79  ? 247 ASP B C   1 
ATOM   3670 O O   . ASP B 2 247 ? 137.816 128.820 94.128  1.00 11.79  ? 247 ASP B O   1 
ATOM   3671 C CB  . ASP B 2 247 ? 136.038 128.479 91.915  1.00 11.79  ? 247 ASP B CB  1 
ATOM   3672 C CG  . ASP B 2 247 ? 136.062 129.920 91.470  1.00 11.79  ? 247 ASP B CG  1 
ATOM   3673 O OD1 . ASP B 2 247 ? 135.691 130.794 92.276  1.00 11.79  ? 247 ASP B OD1 1 
ATOM   3674 O OD2 . ASP B 2 247 ? 136.457 130.183 90.317  1.00 11.79  ? 247 ASP B OD2 1 
ATOM   3675 N N   . ALA B 2 248 ? 136.138 129.879 95.199  1.00 12.36  ? 248 ALA B N   1 
ATOM   3676 C CA  . ALA B 2 248 ? 136.994 130.546 96.178  1.00 12.36  ? 248 ALA B CA  1 
ATOM   3677 C C   . ALA B 2 248 ? 137.925 131.559 95.516  1.00 12.36  ? 248 ALA B C   1 
ATOM   3678 O O   . ALA B 2 248 ? 139.114 131.620 95.826  1.00 12.36  ? 248 ALA B O   1 
ATOM   3679 C CB  . ALA B 2 248 ? 137.799 129.530 96.990  1.00 12.36  ? 248 ALA B CB  1 
ATOM   3680 N N   . THR B 2 249 ? 137.383 132.362 94.603  1.00 13.76  ? 249 THR B N   1 
ATOM   3681 C CA  . THR B 2 249 ? 138.139 133.439 93.985  1.00 13.76  ? 249 THR B CA  1 
ATOM   3682 C C   . THR B 2 249 ? 137.190 134.559 93.595  1.00 13.76  ? 249 THR B C   1 
ATOM   3683 O O   . THR B 2 249 ? 135.987 134.344 93.424  1.00 13.76  ? 249 THR B O   1 
ATOM   3684 C CB  . THR B 2 249 ? 138.910 132.978 92.742  1.00 13.76  ? 249 THR B CB  1 
ATOM   3685 O OG1 . THR B 2 249 ? 137.999 132.404 91.799  1.00 13.76  ? 249 THR B OG1 1 
ATOM   3686 C CG2 . THR B 2 249 ? 139.976 131.960 93.104  1.00 13.76  ? 249 THR B CG2 1 
ATOM   3687 N N   . CYS B 2 250 ? 137.747 135.758 93.462  1.00 15.27  ? 250 CYS B N   1 
ATOM   3688 C CA  . CYS B 2 250 ? 137.039 136.919 92.950  1.00 15.27  ? 250 CYS B CA  1 
ATOM   3689 C C   . CYS B 2 250 ? 137.783 137.434 91.729  1.00 15.27  ? 250 CYS B C   1 
ATOM   3690 O O   . CYS B 2 250 ? 139.015 137.382 91.679  1.00 15.27  ? 250 CYS B O   1 
ATOM   3691 C CB  . CYS B 2 250 ? 136.935 138.022 94.004  1.00 15.27  ? 250 CYS B CB  1 
ATOM   3692 S SG  . CYS B 2 250 ? 136.027 137.550 95.487  1.00 15.27  ? 250 CYS B SG  1 
ATOM   3693 N N   . ARG B 2 251 ? 137.039 137.921 90.743  1.00 16.39  ? 251 ARG B N   1 
ATOM   3694 C CA  . ARG B 2 251 ? 137.623 138.424 89.511  1.00 16.39  ? 251 ARG B CA  1 
ATOM   3695 C C   . ARG B 2 251 ? 136.961 139.740 89.138  1.00 16.39  ? 251 ARG B C   1 
ATOM   3696 O O   . ARG B 2 251 ? 135.786 139.967 89.430  1.00 16.39  ? 251 ARG B O   1 
ATOM   3697 C CB  . ARG B 2 251 ? 137.476 137.412 88.364  1.00 16.39  ? 251 ARG B CB  1 
ATOM   3698 C CG  . ARG B 2 251 ? 137.976 136.008 88.698  1.00 16.39  ? 251 ARG B CG  1 
ATOM   3699 C CD  . ARG B 2 251 ? 137.319 134.940 87.837  1.00 16.39  ? 251 ARG B CD  1 
ATOM   3700 N NE  . ARG B 2 251 ? 137.708 133.595 88.242  1.00 16.39  ? 251 ARG B NE  1 
ATOM   3701 C CZ  . ARG B 2 251 ? 138.870 133.030 87.945  1.00 16.39  ? 251 ARG B CZ  1 
ATOM   3702 N NH1 . ARG B 2 251 ? 139.784 133.662 87.228  1.00 16.39  ? 251 ARG B NH1 1 
ATOM   3703 N NH2 . ARG B 2 251 ? 139.121 131.799 88.380  1.00 16.39  ? 251 ARG B NH2 1 
ATOM   3704 N N   . LEU B 2 252 ? 137.734 140.607 88.489  1.00 15.02  ? 252 LEU B N   1 
ATOM   3705 C CA  . LEU B 2 252 ? 137.290 141.944 88.115  1.00 15.02  ? 252 LEU B CA  1 
ATOM   3706 C C   . LEU B 2 252 ? 137.250 142.039 86.597  1.00 15.02  ? 252 LEU B C   1 
ATOM   3707 O O   . LEU B 2 252 ? 138.269 141.825 85.933  1.00 15.02  ? 252 LEU B O   1 
ATOM   3708 C CB  . LEU B 2 252 ? 138.223 143.005 88.702  1.00 15.02  ? 252 LEU B CB  1 
ATOM   3709 C CG  . LEU B 2 252 ? 137.767 144.463 88.643  1.00 15.02  ? 252 LEU B CG  1 
ATOM   3710 C CD1 . LEU B 2 252 ? 138.269 145.218 89.856  1.00 15.02  ? 252 LEU B CD1 1 
ATOM   3711 C CD2 . LEU B 2 252 ? 138.254 145.132 87.375  1.00 15.02  ? 252 LEU B CD2 1 
ATOM   3712 N N   . PHE B 2 253 ? 136.079 142.360 86.056  1.00 16.11  ? 253 PHE B N   1 
ATOM   3713 C CA  . PHE B 2 253 ? 135.884 142.516 84.623  1.00 16.11  ? 253 PHE B CA  1 
ATOM   3714 C C   . PHE B 2 253 ? 135.720 143.989 84.279  1.00 16.11  ? 253 PHE B C   1 
ATOM   3715 O O   . PHE B 2 253 ? 135.266 144.789 85.100  1.00 16.11  ? 253 PHE B O   1 
ATOM   3716 C CB  . PHE B 2 253 ? 134.655 141.743 84.145  1.00 16.11  ? 253 PHE B CB  1 
ATOM   3717 C CG  . PHE B 2 253 ? 134.595 140.331 84.640  1.00 16.11  ? 253 PHE B CG  1 
ATOM   3718 C CD1 . PHE B 2 253 ? 134.112 140.044 85.902  1.00 16.11  ? 253 PHE B CD1 1 
ATOM   3719 C CD2 . PHE B 2 253 ? 135.019 139.288 83.840  1.00 16.11  ? 253 PHE B CD2 1 
ATOM   3720 C CE1 . PHE B 2 253 ? 134.055 138.746 86.357  1.00 16.11  ? 253 PHE B CE1 1 
ATOM   3721 C CE2 . PHE B 2 253 ? 134.964 137.988 84.291  1.00 16.11  ? 253 PHE B CE2 1 
ATOM   3722 C CZ  . PHE B 2 253 ? 134.480 137.717 85.551  1.00 16.11  ? 253 PHE B CZ  1 
ATOM   3723 N N   . ASP B 2 254 ? 136.095 144.341 83.053  1.00 29.12  ? 254 ASP B N   1 
ATOM   3724 C CA  . ASP B 2 254 ? 135.978 145.704 82.554  1.00 29.12  ? 254 ASP B CA  1 
ATOM   3725 C C   . ASP B 2 254 ? 135.162 145.697 81.272  1.00 29.12  ? 254 ASP B C   1 
ATOM   3726 O O   . ASP B 2 254 ? 135.487 144.971 80.327  1.00 29.12  ? 254 ASP B O   1 
ATOM   3727 C CB  . ASP B 2 254 ? 137.357 146.319 82.315  1.00 29.12  ? 254 ASP B CB  1 
ATOM   3728 C CG  . ASP B 2 254 ? 138.271 145.401 81.547  1.00 29.12  ? 254 ASP B CG  1 
ATOM   3729 O OD1 . ASP B 2 254 ? 137.834 144.284 81.213  1.00 29.12  ? 254 ASP B OD1 1 
ATOM   3730 O OD2 . ASP B 2 254 ? 139.426 145.789 81.282  1.00 29.12  ? 254 ASP B OD2 1 
ATOM   3731 N N   . LEU B 2 255 ? 134.109 146.514 81.241  1.00 25.35  ? 255 LEU B N   1 
ATOM   3732 C CA  . LEU B 2 255 ? 133.160 146.463 80.135  1.00 25.35  ? 255 LEU B CA  1 
ATOM   3733 C C   . LEU B 2 255 ? 133.832 146.804 78.813  1.00 25.35  ? 255 LEU B C   1 
ATOM   3734 O O   . LEU B 2 255 ? 133.620 146.125 77.802  1.00 25.35  ? 255 LEU B O   1 
ATOM   3735 C CB  . LEU B 2 255 ? 131.997 147.418 80.403  1.00 25.35  ? 255 LEU B CB  1 
ATOM   3736 C CG  . LEU B 2 255 ? 131.445 147.449 81.830  1.00 25.35  ? 255 LEU B CG  1 
ATOM   3737 C CD1 . LEU B 2 255 ? 130.208 148.322 81.898  1.00 25.35  ? 255 LEU B CD1 1 
ATOM   3738 C CD2 . LEU B 2 255 ? 131.137 146.051 82.327  1.00 25.35  ? 255 LEU B CD2 1 
ATOM   3739 N N   . ARG B 2 256 ? 134.651 147.855 78.798  1.00 37.82  ? 256 ARG B N   1 
ATOM   3740 C CA  . ARG B 2 256 ? 135.205 148.340 77.538  1.00 37.82  ? 256 ARG B CA  1 
ATOM   3741 C C   . ARG B 2 256 ? 136.194 147.343 76.944  1.00 37.82  ? 256 ARG B C   1 
ATOM   3742 O O   . ARG B 2 256 ? 136.162 147.069 75.739  1.00 37.82  ? 256 ARG B O   1 
ATOM   3743 C CB  . ARG B 2 256 ? 135.865 149.702 77.750  1.00 37.82  ? 256 ARG B CB  1 
ATOM   3744 C CG  . ARG B 2 256 ? 134.867 150.837 77.923  1.00 37.82  ? 256 ARG B CG  1 
ATOM   3745 C CD  . ARG B 2 256 ? 135.531 152.101 78.441  1.00 37.82  ? 256 ARG B CD  1 
ATOM   3746 N NE  . ARG B 2 256 ? 135.958 151.968 79.829  1.00 37.82  ? 256 ARG B NE  1 
ATOM   3747 C CZ  . ARG B 2 256 ? 136.780 152.806 80.446  1.00 37.82  ? 256 ARG B CZ  1 
ATOM   3748 N NH1 . ARG B 2 256 ? 137.282 153.861 79.827  1.00 37.82  ? 256 ARG B NH1 1 
ATOM   3749 N NH2 . ARG B 2 256 ? 137.107 152.578 81.715  1.00 37.82  ? 256 ARG B NH2 1 
ATOM   3750 N N   . ALA B 2 257 ? 137.083 146.788 77.770  1.00 43.64  ? 257 ALA B N   1 
ATOM   3751 C CA  . ALA B 2 257 ? 138.035 145.808 77.259  1.00 43.64  ? 257 ALA B CA  1 
ATOM   3752 C C   . ALA B 2 257 ? 137.367 144.465 76.997  1.00 43.64  ? 257 ALA B C   1 
ATOM   3753 O O   . ALA B 2 257 ? 137.836 143.697 76.151  1.00 43.64  ? 257 ALA B O   1 
ATOM   3754 C CB  . ALA B 2 257 ? 139.196 145.634 78.234  1.00 43.64  ? 257 ALA B CB  1 
ATOM   3755 N N   . ASP B 2 258 ? 136.289 144.160 77.720  1.00 43.27  ? 258 ASP B N   1 
ATOM   3756 C CA  . ASP B 2 258 ? 135.469 142.988 77.437  1.00 43.27  ? 258 ASP B CA  1 
ATOM   3757 C C   . ASP B 2 258 ? 136.151 141.686 77.839  1.00 43.27  ? 258 ASP B C   1 
ATOM   3758 O O   . ASP B 2 258 ? 135.848 140.631 77.274  1.00 43.27  ? 258 ASP B O   1 
ATOM   3759 C CB  . ASP B 2 258 ? 135.110 142.944 75.950  1.00 43.27  ? 258 ASP B CB  1 
ATOM   3760 C CG  . ASP B 2 258 ? 133.911 142.070 75.666  1.00 43.27  ? 258 ASP B CG  1 
ATOM   3761 O OD1 . ASP B 2 258 ? 132.845 142.306 76.273  1.00 43.27  ? 258 ASP B OD1 1 
ATOM   3762 O OD2 . ASP B 2 258 ? 134.032 141.142 74.839  1.00 43.27  ? 258 ASP B OD2 1 
ATOM   3763 N N   . GLN B 2 259 ? 137.064 141.737 78.807  1.00 39.19  ? 259 GLN B N   1 
ATOM   3764 C CA  . GLN B 2 259 ? 137.742 140.529 79.252  1.00 39.19  ? 259 GLN B CA  1 
ATOM   3765 C C   . GLN B 2 259 ? 138.202 140.699 80.692  1.00 39.19  ? 259 GLN B C   1 
ATOM   3766 O O   . GLN B 2 259 ? 138.246 141.808 81.228  1.00 39.19  ? 259 GLN B O   1 
ATOM   3767 C CB  . GLN B 2 259 ? 138.932 140.183 78.352  1.00 39.19  ? 259 GLN B CB  1 
ATOM   3768 C CG  . GLN B 2 259 ? 140.156 141.041 78.583  1.00 39.19  ? 259 GLN B CG  1 
ATOM   3769 C CD  . GLN B 2 259 ? 141.133 140.963 77.433  1.00 39.19  ? 259 GLN B CD  1 
ATOM   3770 O OE1 . GLN B 2 259 ? 142.084 140.183 77.464  1.00 39.19  ? 259 GLN B OE1 1 
ATOM   3771 N NE2 . GLN B 2 259 ? 140.899 141.765 76.404  1.00 39.19  ? 259 GLN B NE2 1 
ATOM   3772 N N   . GLU B 2 260 ? 138.549 139.574 81.310  1.00 26.38  ? 260 GLU B N   1 
ATOM   3773 C CA  . GLU B 2 260 ? 138.931 139.569 82.714  1.00 26.38  ? 260 GLU B CA  1 
ATOM   3774 C C   . GLU B 2 260 ? 140.223 140.345 82.929  1.00 26.38  ? 260 GLU B C   1 
ATOM   3775 O O   . GLU B 2 260 ? 141.112 140.350 82.074  1.00 26.38  ? 260 GLU B O   1 
ATOM   3776 C CB  . GLU B 2 260 ? 139.098 138.134 83.199  1.00 26.38  ? 260 GLU B CB  1 
ATOM   3777 C CG  . GLU B 2 260 ? 139.220 138.007 84.692  1.00 26.38  ? 260 GLU B CG  1 
ATOM   3778 C CD  . GLU B 2 260 ? 138.572 136.747 85.201  1.00 26.38  ? 260 GLU B CD  1 
ATOM   3779 O OE1 . GLU B 2 260 ? 139.264 135.713 85.296  1.00 26.38  ? 260 GLU B OE1 1 
ATOM   3780 O OE2 . GLU B 2 260 ? 137.359 136.788 85.488  1.00 26.38  ? 260 GLU B OE2 1 
ATOM   3781 N N   . LEU B 2 261 ? 140.327 140.998 84.086  1.00 28.53  ? 261 LEU B N   1 
ATOM   3782 C CA  . LEU B 2 261 ? 141.475 141.834 84.417  1.00 28.53  ? 261 LEU B CA  1 
ATOM   3783 C C   . LEU B 2 261 ? 142.331 141.265 85.539  1.00 28.53  ? 261 LEU B C   1 
ATOM   3784 O O   . LEU B 2 261 ? 143.554 141.178 85.396  1.00 28.53  ? 261 LEU B O   1 
ATOM   3785 C CB  . LEU B 2 261 ? 141.002 143.243 84.802  1.00 28.53  ? 261 LEU B CB  1 
ATOM   3786 C CG  . LEU B 2 261 ? 140.843 144.260 83.669  1.00 28.53  ? 261 LEU B CG  1 
ATOM   3787 C CD1 . LEU B 2 261 ? 140.309 145.569 84.216  1.00 28.53  ? 261 LEU B CD1 1 
ATOM   3788 C CD2 . LEU B 2 261 ? 142.159 144.484 82.944  1.00 28.53  ? 261 LEU B CD2 1 
ATOM   3789 N N   . MET B 2 262 ? 141.724 140.878 86.659  1.00 26.48  ? 262 MET B N   1 
ATOM   3790 C CA  . MET B 2 262 ? 142.482 140.460 87.830  1.00 26.48  ? 262 MET B CA  1 
ATOM   3791 C C   . MET B 2 262 ? 141.735 139.340 88.538  1.00 26.48  ? 262 MET B C   1 
ATOM   3792 O O   . MET B 2 262 ? 140.521 139.187 88.392  1.00 26.48  ? 262 MET B O   1 
ATOM   3793 C CB  . MET B 2 262 ? 142.712 141.639 88.783  1.00 26.48  ? 262 MET B CB  1 
ATOM   3794 C CG  . MET B 2 262 ? 143.645 141.349 89.949  1.00 26.48  ? 262 MET B CG  1 
ATOM   3795 S SD  . MET B 2 262 ? 145.326 140.948 89.434  1.00 26.48  ? 262 MET B SD  1 
ATOM   3796 C CE  . MET B 2 262 ? 146.037 142.585 89.306  1.00 26.48  ? 262 MET B CE  1 
ATOM   3797 N N   . THR B 2 263 ? 142.483 138.550 89.307  1.00 19.51  ? 263 THR B N   1 
ATOM   3798 C CA  . THR B 2 263 ? 141.911 137.490 90.126  1.00 19.51  ? 263 THR B CA  1 
ATOM   3799 C C   . THR B 2 263 ? 142.603 137.480 91.479  1.00 19.51  ? 263 THR B C   1 
ATOM   3800 O O   . THR B 2 263 ? 143.829 137.601 91.553  1.00 19.51  ? 263 THR B O   1 
ATOM   3801 C CB  . THR B 2 263 ? 142.052 136.120 89.452  1.00 19.51  ? 263 THR B CB  1 
ATOM   3802 O OG1 . THR B 2 263 ? 141.304 135.147 90.190  1.00 19.51  ? 263 THR B OG1 1 
ATOM   3803 C CG2 . THR B 2 263 ? 143.511 135.696 89.390  1.00 19.51  ? 263 THR B CG2 1 
ATOM   3804 N N   . TYR B 2 264 ? 141.818 137.330 92.540  1.00 15.63  ? 264 TYR B N   1 
ATOM   3805 C CA  . TYR B 2 264 ? 142.308 137.376 93.915  1.00 15.63  ? 264 TYR B CA  1 
ATOM   3806 C C   . TYR B 2 264 ? 142.168 135.981 94.514  1.00 15.63  ? 264 TYR B C   1 
ATOM   3807 O O   . TYR B 2 264 ? 141.081 135.587 94.945  1.00 15.63  ? 264 TYR B O   1 
ATOM   3808 C CB  . TYR B 2 264 ? 141.535 138.412 94.724  1.00 15.63  ? 264 TYR B CB  1 
ATOM   3809 C CG  . TYR B 2 264 ? 141.326 139.715 93.993  1.00 15.63  ? 264 TYR B CG  1 
ATOM   3810 C CD1 . TYR B 2 264 ? 142.401 140.517 93.649  1.00 15.63  ? 264 TYR B CD1 1 
ATOM   3811 C CD2 . TYR B 2 264 ? 140.059 140.140 93.639  1.00 15.63  ? 264 TYR B CD2 1 
ATOM   3812 C CE1 . TYR B 2 264 ? 142.218 141.703 92.978  1.00 15.63  ? 264 TYR B CE1 1 
ATOM   3813 C CE2 . TYR B 2 264 ? 139.867 141.324 92.967  1.00 15.63  ? 264 TYR B CE2 1 
ATOM   3814 C CZ  . TYR B 2 264 ? 140.950 142.102 92.640  1.00 15.63  ? 264 TYR B CZ  1 
ATOM   3815 O OH  . TYR B 2 264 ? 140.765 143.284 91.971  1.00 15.63  ? 264 TYR B OH  1 
ATOM   3816 N N   . SER B 2 265 ? 143.274 135.242 94.550  1.00 19.41  ? 265 SER B N   1 
ATOM   3817 C CA  . SER B 2 265 ? 143.277 133.861 95.008  1.00 19.41  ? 265 SER B CA  1 
ATOM   3818 C C   . SER B 2 265 ? 144.447 133.624 95.949  1.00 19.41  ? 265 SER B C   1 
ATOM   3819 O O   . SER B 2 265 ? 145.553 134.120 95.717  1.00 19.41  ? 265 SER B O   1 
ATOM   3820 C CB  . SER B 2 265 ? 143.366 132.888 93.829  1.00 19.41  ? 265 SER B CB  1 
ATOM   3821 O OG  . SER B 2 265 ? 144.655 132.922 93.242  1.00 19.41  ? 265 SER B OG  1 
ATOM   3822 N N   . HIS B 2 266 ? 144.194 132.860 97.009  1.00 21.54  ? 266 HIS B N   1 
ATOM   3823 C CA  . HIS B 2 266 ? 145.224 132.433 97.943  1.00 21.54  ? 266 HIS B CA  1 
ATOM   3824 C C   . HIS B 2 266 ? 145.048 130.950 98.230  1.00 21.54  ? 266 HIS B C   1 
ATOM   3825 O O   . HIS B 2 266 ? 143.922 130.448 98.276  1.00 21.54  ? 266 HIS B O   1 
ATOM   3826 C CB  . HIS B 2 266 ? 145.166 133.226 99.250  1.00 21.54  ? 266 HIS B CB  1 
ATOM   3827 C CG  . HIS B 2 266 ? 146.470 133.282 99.979  1.00 21.54  ? 266 HIS B CG  1 
ATOM   3828 N ND1 . HIS B 2 266 ? 146.961 132.223 100.710 1.00 21.54  ? 266 HIS B ND1 1 
ATOM   3829 C CD2 . HIS B 2 266 ? 147.390 134.270 100.087 1.00 21.54  ? 266 HIS B CD2 1 
ATOM   3830 C CE1 . HIS B 2 266 ? 148.124 132.556 101.238 1.00 21.54  ? 266 HIS B CE1 1 
ATOM   3831 N NE2 . HIS B 2 266 ? 148.408 133.794 100.876 1.00 21.54  ? 266 HIS B NE2 1 
ATOM   3832 N N   . ASP B 2 267 ? 146.169 130.254 98.431  1.00 27.29  ? 267 ASP B N   1 
ATOM   3833 C CA  . ASP B 2 267 ? 146.116 128.814 98.656  1.00 27.29  ? 267 ASP B CA  1 
ATOM   3834 C C   . ASP B 2 267 ? 145.318 128.486 99.911  1.00 27.29  ? 267 ASP B C   1 
ATOM   3835 O O   . ASP B 2 267 ? 144.535 127.530 99.932  1.00 27.29  ? 267 ASP B O   1 
ATOM   3836 C CB  . ASP B 2 267 ? 147.532 128.251 98.759  1.00 27.29  ? 267 ASP B CB  1 
ATOM   3837 C CG  . ASP B 2 267 ? 148.276 128.300 97.438  1.00 27.29  ? 267 ASP B CG  1 
ATOM   3838 O OD1 . ASP B 2 267 ? 147.616 128.227 96.381  1.00 27.29  ? 267 ASP B OD1 1 
ATOM   3839 O OD2 . ASP B 2 267 ? 149.519 128.412 97.458  1.00 27.29  ? 267 ASP B OD2 1 
ATOM   3840 N N   . ASN B 2 268 ? 145.506 129.274 100.970 1.00 25.01  ? 268 ASN B N   1 
ATOM   3841 C CA  . ASN B 2 268 ? 144.830 128.995 102.231 1.00 25.01  ? 268 ASN B CA  1 
ATOM   3842 C C   . ASN B 2 268 ? 143.316 129.024 102.069 1.00 25.01  ? 268 ASN B C   1 
ATOM   3843 O O   . ASN B 2 268 ? 142.602 128.227 102.688 1.00 25.01  ? 268 ASN B O   1 
ATOM   3844 C CB  . ASN B 2 268 ? 145.268 130.007 103.289 1.00 25.01  ? 268 ASN B CB  1 
ATOM   3845 C CG  . ASN B 2 268 ? 146.706 129.811 103.717 1.00 25.01  ? 268 ASN B CG  1 
ATOM   3846 O OD1 . ASN B 2 268 ? 147.162 128.685 103.904 1.00 25.01  ? 268 ASN B OD1 1 
ATOM   3847 N ND2 . ASN B 2 268 ? 147.429 130.912 103.876 1.00 25.01  ? 268 ASN B ND2 1 
ATOM   3848 N N   . ILE B 2 269 ? 142.808 129.936 101.245 1.00 19.26  ? 269 ILE B N   1 
ATOM   3849 C CA  . ILE B 2 269 ? 141.368 130.117 101.087 1.00 19.26  ? 269 ILE B CA  1 
ATOM   3850 C C   . ILE B 2 269 ? 140.850 129.016 100.168 1.00 19.26  ? 269 ILE B C   1 
ATOM   3851 O O   . ILE B 2 269 ? 141.238 128.934 99.002  1.00 19.26  ? 269 ILE B O   1 
ATOM   3852 C CB  . ILE B 2 269 ? 141.036 131.505 100.531 1.00 19.26  ? 269 ILE B CB  1 
ATOM   3853 C CG1 . ILE B 2 269 ? 141.456 132.590 101.523 1.00 19.26  ? 269 ILE B CG1 1 
ATOM   3854 C CG2 . ILE B 2 269 ? 139.551 131.615 100.242 1.00 19.26  ? 269 ILE B CG2 1 
ATOM   3855 C CD1 . ILE B 2 269 ? 141.461 133.983 100.937 1.00 19.26  ? 269 ILE B CD1 1 
ATOM   3856 N N   . ILE B 2 270 ? 139.973 128.164 100.697 1.00 17.23  ? 270 ILE B N   1 
ATOM   3857 C CA  . ILE B 2 270 ? 139.399 127.067 99.928  1.00 17.23  ? 270 ILE B CA  1 
ATOM   3858 C C   . ILE B 2 270 ? 137.885 127.048 100.084 1.00 17.23  ? 270 ILE B C   1 
ATOM   3859 O O   . ILE B 2 270 ? 137.249 126.000 99.929  1.00 17.23  ? 270 ILE B O   1 
ATOM   3860 C CB  . ILE B 2 270 ? 140.017 125.721 100.349 1.00 17.23  ? 270 ILE B CB  1 
ATOM   3861 C CG1 . ILE B 2 270 ? 139.717 125.427 101.820 1.00 17.23  ? 270 ILE B CG1 1 
ATOM   3862 C CG2 . ILE B 2 270 ? 141.514 125.731 100.100 1.00 17.23  ? 270 ILE B CG2 1 
ATOM   3863 C CD1 . ILE B 2 270 ? 140.089 124.026 102.249 1.00 17.23  ? 270 ILE B CD1 1 
ATOM   3864 N N   . CYS B 2 271 ? 137.297 128.199 100.399 1.00 14.48  ? 271 CYS B N   1 
ATOM   3865 C CA  . CYS B 2 271 ? 135.859 128.325 100.575 1.00 14.48  ? 271 CYS B CA  1 
ATOM   3866 C C   . CYS B 2 271 ? 135.316 129.422 99.668  1.00 14.48  ? 271 CYS B C   1 
ATOM   3867 O O   . CYS B 2 271 ? 136.061 130.257 99.151  1.00 14.48  ? 271 CYS B O   1 
ATOM   3868 C CB  . CYS B 2 271 ? 135.505 128.628 102.034 1.00 14.48  ? 271 CYS B CB  1 
ATOM   3869 S SG  . CYS B 2 271 ? 136.152 130.199 102.622 1.00 14.48  ? 271 CYS B SG  1 
ATOM   3870 N N   . GLY B 2 272 ? 133.997 129.406 99.476  1.00 11.42  ? 272 GLY B N   1 
ATOM   3871 C CA  . GLY B 2 272 ? 133.365 130.328 98.559  1.00 11.42  ? 272 GLY B CA  1 
ATOM   3872 C C   . GLY B 2 272 ? 133.142 131.706 99.149  1.00 11.42  ? 272 GLY B C   1 
ATOM   3873 O O   . GLY B 2 272 ? 133.334 131.950 100.338 1.00 11.42  ? 272 GLY B O   1 
ATOM   3874 N N   . ILE B 2 273 ? 132.722 132.622 98.280  1.00 17.64  ? 273 ILE B N   1 
ATOM   3875 C CA  . ILE B 2 273 ? 132.437 134.005 98.638  1.00 17.64  ? 273 ILE B CA  1 
ATOM   3876 C C   . ILE B 2 273 ? 130.930 134.205 98.599  1.00 17.64  ? 273 ILE B C   1 
ATOM   3877 O O   . ILE B 2 273 ? 130.258 133.725 97.679  1.00 17.64  ? 273 ILE B O   1 
ATOM   3878 C CB  . ILE B 2 273 ? 133.147 134.989 97.694  1.00 17.64  ? 273 ILE B CB  1 
ATOM   3879 C CG1 . ILE B 2 273 ? 134.658 134.759 97.732  1.00 17.64  ? 273 ILE B CG1 1 
ATOM   3880 C CG2 . ILE B 2 273 ? 132.821 136.418 98.073  1.00 17.64  ? 273 ILE B CG2 1 
ATOM   3881 C CD1 . ILE B 2 273 ? 135.160 133.831 96.658  1.00 17.64  ? 273 ILE B CD1 1 
ATOM   3882 N N   . THR B 2 274 ? 130.400 134.909 99.598  1.00 13.30  ? 274 THR B N   1 
ATOM   3883 C CA  . THR B 2 274 ? 128.964 135.131 99.724  1.00 13.30  ? 274 THR B CA  1 
ATOM   3884 C C   . THR B 2 274 ? 128.542 136.567 99.442  1.00 13.30  ? 274 THR B C   1 
ATOM   3885 O O   . THR B 2 274 ? 127.340 136.839 99.399  1.00 13.30  ? 274 THR B O   1 
ATOM   3886 C CB  . THR B 2 274 ? 128.496 134.749 101.132 1.00 13.30  ? 274 THR B CB  1 
ATOM   3887 O OG1 . THR B 2 274 ? 129.124 135.601 102.094 1.00 13.30  ? 274 THR B OG1 1 
ATOM   3888 C CG2 . THR B 2 274 ? 128.844 133.311 101.438 1.00 13.30  ? 274 THR B CG2 1 
ATOM   3889 N N   . SER B 2 275 ? 129.486 137.484 99.253  1.00 29.40  ? 275 SER B N   1 
ATOM   3890 C CA  . SER B 2 275 ? 129.155 138.884 99.031  1.00 29.40  ? 275 SER B CA  1 
ATOM   3891 C C   . SER B 2 275 ? 130.425 139.632 98.670  1.00 29.40  ? 275 SER B C   1 
ATOM   3892 O O   . SER B 2 275 ? 131.534 139.182 98.967  1.00 29.40  ? 275 SER B O   1 
ATOM   3893 C CB  . SER B 2 275 ? 128.503 139.504 100.265 1.00 29.40  ? 275 SER B CB  1 
ATOM   3894 O OG  . SER B 2 275 ? 129.316 139.312 101.406 1.00 29.40  ? 275 SER B OG  1 
ATOM   3895 N N   . VAL B 2 276 ? 130.249 140.782 98.019  1.00 22.95  ? 276 VAL B N   1 
ATOM   3896 C CA  . VAL B 2 276 ? 131.360 141.656 97.661  1.00 22.95  ? 276 VAL B CA  1 
ATOM   3897 C C   . VAL B 2 276 ? 130.859 143.090 97.650  1.00 22.95  ? 276 VAL B C   1 
ATOM   3898 O O   . VAL B 2 276 ? 129.664 143.351 97.509  1.00 22.95  ? 276 VAL B O   1 
ATOM   3899 C CB  . VAL B 2 276 ? 131.982 141.304 96.289  1.00 22.95  ? 276 VAL B CB  1 
ATOM   3900 C CG1 . VAL B 2 276 ? 132.785 140.025 96.382  1.00 22.95  ? 276 VAL B CG1 1 
ATOM   3901 C CG2 . VAL B 2 276 ? 130.908 141.186 95.230  1.00 22.95  ? 276 VAL B CG2 1 
ATOM   3902 N N   . SER B 2 277 ? 131.788 144.027 97.810  1.00 20.75  ? 277 SER B N   1 
ATOM   3903 C CA  . SER B 2 277 ? 131.474 145.444 97.716  1.00 20.75  ? 277 SER B CA  1 
ATOM   3904 C C   . SER B 2 277 ? 132.769 146.233 97.745  1.00 20.75  ? 277 SER B C   1 
ATOM   3905 O O   . SER B 2 277 ? 133.692 145.884 98.480  1.00 20.75  ? 277 SER B O   1 
ATOM   3906 C CB  . SER B 2 277 ? 130.563 145.891 98.861  1.00 20.75  ? 277 SER B CB  1 
ATOM   3907 O OG  . SER B 2 277 ? 131.331 146.253 99.992  1.00 20.75  ? 277 SER B OG  1 
ATOM   3908 N N   . PHE B 2 278 ? 132.827 147.293 96.951  1.00 17.78  ? 278 PHE B N   1 
ATOM   3909 C CA  . PHE B 2 278 ? 133.974 148.183 96.936  1.00 17.78  ? 278 PHE B CA  1 
ATOM   3910 C C   . PHE B 2 278 ? 133.817 149.266 97.997  1.00 17.78  ? 278 PHE B C   1 
ATOM   3911 O O   . PHE B 2 278 ? 132.724 149.521 98.504  1.00 17.78  ? 278 PHE B O   1 
ATOM   3912 C CB  . PHE B 2 278 ? 134.141 148.831 95.561  1.00 17.78  ? 278 PHE B CB  1 
ATOM   3913 C CG  . PHE B 2 278 ? 134.788 147.941 94.539  1.00 17.78  ? 278 PHE B CG  1 
ATOM   3914 C CD1 . PHE B 2 278 ? 134.028 147.073 93.778  1.00 17.78  ? 278 PHE B CD1 1 
ATOM   3915 C CD2 . PHE B 2 278 ? 136.153 147.986 94.329  1.00 17.78  ? 278 PHE B CD2 1 
ATOM   3916 C CE1 . PHE B 2 278 ? 134.618 146.261 92.835  1.00 17.78  ? 278 PHE B CE1 1 
ATOM   3917 C CE2 . PHE B 2 278 ? 136.747 147.176 93.386  1.00 17.78  ? 278 PHE B CE2 1 
ATOM   3918 C CZ  . PHE B 2 278 ? 135.978 146.314 92.638  1.00 17.78  ? 278 PHE B CZ  1 
ATOM   3919 N N   . SER B 2 279 ? 134.933 149.908 98.325  1.00 25.73  ? 279 SER B N   1 
ATOM   3920 C CA  . SER B 2 279 ? 134.913 151.073 99.197  1.00 25.73  ? 279 SER B CA  1 
ATOM   3921 C C   . SER B 2 279 ? 134.438 152.276 98.384  1.00 25.73  ? 279 SER B C   1 
ATOM   3922 O O   . SER B 2 279 ? 133.986 152.143 97.244  1.00 25.73  ? 279 SER B O   1 
ATOM   3923 C CB  . SER B 2 279 ? 136.288 151.293 99.817  1.00 25.73  ? 279 SER B CB  1 
ATOM   3924 O OG  . SER B 2 279 ? 137.238 151.656 98.835  1.00 25.73  ? 279 SER B OG  1 
ATOM   3925 N N   . LYS B 2 280 ? 134.521 153.475 98.962  1.00 25.73  ? 280 LYS B N   1 
ATOM   3926 C CA  . LYS B 2 280 ? 134.031 154.653 98.254  1.00 25.73  ? 280 LYS B CA  1 
ATOM   3927 C C   . LYS B 2 280 ? 134.913 154.994 97.060  1.00 25.73  ? 280 LYS B C   1 
ATOM   3928 O O   . LYS B 2 280 ? 134.405 155.362 95.995  1.00 25.73  ? 280 LYS B O   1 
ATOM   3929 C CB  . LYS B 2 280 ? 133.946 155.844 99.205  1.00 25.73  ? 280 LYS B CB  1 
ATOM   3930 C CG  . LYS B 2 280 ? 133.563 157.140 98.513  1.00 25.73  ? 280 LYS B CG  1 
ATOM   3931 C CD  . LYS B 2 280 ? 132.779 158.053 99.436  1.00 25.73  ? 280 LYS B CD  1 
ATOM   3932 C CE  . LYS B 2 280 ? 132.257 159.268 98.695  1.00 25.73  ? 280 LYS B CE  1 
ATOM   3933 N NZ  . LYS B 2 280 ? 131.150 158.917 97.765  1.00 25.73  ? 280 LYS B NZ  1 
ATOM   3934 N N   . SER B 2 281 ? 136.230 154.891 97.216  1.00 26.05  ? 281 SER B N   1 
ATOM   3935 C CA  . SER B 2 281 ? 137.164 155.219 96.150  1.00 26.05  ? 281 SER B CA  1 
ATOM   3936 C C   . SER B 2 281 ? 137.507 154.026 95.272  1.00 26.05  ? 281 SER B C   1 
ATOM   3937 O O   . SER B 2 281 ? 138.219 154.192 94.278  1.00 26.05  ? 281 SER B O   1 
ATOM   3938 C CB  . SER B 2 281 ? 138.454 155.798 96.735  1.00 26.05  ? 281 SER B CB  1 
ATOM   3939 O OG  . SER B 2 281 ? 139.236 154.788 97.341  1.00 26.05  ? 281 SER B OG  1 
ATOM   3940 N N   . GLY B 2 282 ? 137.028 152.835 95.610  1.00 21.43  ? 282 GLY B N   1 
ATOM   3941 C CA  . GLY B 2 282 ? 137.296 151.664 94.797  1.00 21.43  ? 282 GLY B CA  1 
ATOM   3942 C C   . GLY B 2 282 ? 138.750 151.242 94.766  1.00 21.43  ? 282 GLY B C   1 
ATOM   3943 O O   . GLY B 2 282 ? 139.260 150.873 93.701  1.00 21.43  ? 282 GLY B O   1 
ATOM   3944 N N   . ARG B 2 283 ? 139.433 151.289 95.909  1.00 30.06  ? 283 ARG B N   1 
ATOM   3945 C CA  . ARG B 2 283 ? 140.790 150.776 96.025  1.00 30.06  ? 283 ARG B CA  1 
ATOM   3946 C C   . ARG B 2 283 ? 140.870 149.494 96.839  1.00 30.06  ? 283 ARG B C   1 
ATOM   3947 O O   . ARG B 2 283 ? 141.904 148.820 96.803  1.00 30.06  ? 283 ARG B O   1 
ATOM   3948 C CB  . ARG B 2 283 ? 141.709 151.835 96.655  1.00 30.06  ? 283 ARG B CB  1 
ATOM   3949 C CG  . ARG B 2 283 ? 143.150 151.385 96.872  1.00 30.06  ? 283 ARG B CG  1 
ATOM   3950 C CD  . ARG B 2 283 ? 143.779 150.859 95.595  1.00 30.06  ? 283 ARG B CD  1 
ATOM   3951 N NE  . ARG B 2 283 ? 145.145 150.395 95.804  1.00 30.06  ? 283 ARG B NE  1 
ATOM   3952 C CZ  . ARG B 2 283 ? 146.180 151.189 96.041  1.00 30.06  ? 283 ARG B CZ  1 
ATOM   3953 N NH1 . ARG B 2 283 ? 146.040 152.502 96.125  1.00 30.06  ? 283 ARG B NH1 1 
ATOM   3954 N NH2 . ARG B 2 283 ? 147.385 150.652 96.196  1.00 30.06  ? 283 ARG B NH2 1 
ATOM   3955 N N   . LEU B 2 284 ? 139.815 149.141 97.563  1.00 21.99  ? 284 LEU B N   1 
ATOM   3956 C CA  . LEU B 2 284 ? 139.742 147.897 98.309  1.00 21.99  ? 284 LEU B CA  1 
ATOM   3957 C C   . LEU B 2 284 ? 138.530 147.105 97.842  1.00 21.99  ? 284 LEU B C   1 
ATOM   3958 O O   . LEU B 2 284 ? 137.685 147.599 97.094  1.00 21.99  ? 284 LEU B O   1 
ATOM   3959 C CB  . LEU B 2 284 ? 139.663 148.161 99.817  1.00 21.99  ? 284 LEU B CB  1 
ATOM   3960 C CG  . LEU B 2 284 ? 140.649 149.192 100.364 1.00 21.99  ? 284 LEU B CG  1 
ATOM   3961 C CD1 . LEU B 2 284 ? 140.360 149.477 101.825 1.00 21.99  ? 284 LEU B CD1 1 
ATOM   3962 C CD2 . LEU B 2 284 ? 142.077 148.717 100.183 1.00 21.99  ? 284 LEU B CD2 1 
ATOM   3963 N N   . LEU B 2 285 ? 138.456 145.856 98.293  1.00 13.14  ? 285 LEU B N   1 
ATOM   3964 C CA  . LEU B 2 285 ? 137.401 144.944 97.852  1.00 13.14  ? 285 LEU B CA  1 
ATOM   3965 C C   . LEU B 2 285 ? 137.088 144.013 99.023  1.00 13.14  ? 285 LEU B C   1 
ATOM   3966 O O   . LEU B 2 285 ? 137.745 142.989 99.211  1.00 13.14  ? 285 LEU B O   1 
ATOM   3967 C CB  . LEU B 2 285 ? 137.833 144.166 96.617  1.00 13.14  ? 285 LEU B CB  1 
ATOM   3968 C CG  . LEU B 2 285 ? 136.737 143.532 95.760  1.00 13.14  ? 285 LEU B CG  1 
ATOM   3969 C CD1 . LEU B 2 285 ? 137.326 142.994 94.477  1.00 13.14  ? 285 LEU B CD1 1 
ATOM   3970 C CD2 . LEU B 2 285 ? 136.021 142.432 96.509  1.00 13.14  ? 285 LEU B CD2 1 
ATOM   3971 N N   . LEU B 2 286 ? 136.080 144.380 99.802  1.00 28.35  ? 286 LEU B N   1 
ATOM   3972 C CA  . LEU B 2 286 ? 135.619 143.506 100.866 1.00 28.35  ? 286 LEU B CA  1 
ATOM   3973 C C   . LEU B 2 286 ? 134.856 142.327 100.275 1.00 28.35  ? 286 LEU B C   1 
ATOM   3974 O O   . LEU B 2 286 ? 134.281 142.414 99.190  1.00 28.35  ? 286 LEU B O   1 
ATOM   3975 C CB  . LEU B 2 286 ? 134.738 144.279 101.844 1.00 28.35  ? 286 LEU B CB  1 
ATOM   3976 C CG  . LEU B 2 286 ? 135.407 145.492 102.494 1.00 28.35  ? 286 LEU B CG  1 
ATOM   3977 C CD1 . LEU B 2 286 ? 134.992 146.785 101.816 1.00 28.35  ? 286 LEU B CD1 1 
ATOM   3978 C CD2 . LEU B 2 286 ? 135.083 145.540 103.971 1.00 28.35  ? 286 LEU B CD2 1 
ATOM   3979 N N   . ALA B 2 287 ? 134.864 141.209 100.994 1.00 18.25  ? 287 ALA B N   1 
ATOM   3980 C CA  . ALA B 2 287 ? 134.199 140.003 100.511 1.00 18.25  ? 287 ALA B CA  1 
ATOM   3981 C C   . ALA B 2 287 ? 134.036 139.038 101.670 1.00 18.25  ? 287 ALA B C   1 
ATOM   3982 O O   . ALA B 2 287 ? 135.017 138.717 102.347 1.00 18.25  ? 287 ALA B O   1 
ATOM   3983 C CB  . ALA B 2 287 ? 134.998 139.360 99.384  1.00 18.25  ? 287 ALA B CB  1 
ATOM   3984 N N   . GLY B 2 288 ? 132.810 138.569 101.895 1.00 14.96  ? 288 GLY B N   1 
ATOM   3985 C CA  . GLY B 2 288 ? 132.529 137.679 103.004 1.00 14.96  ? 288 GLY B CA  1 
ATOM   3986 C C   . GLY B 2 288 ? 132.617 136.227 102.584 1.00 14.96  ? 288 GLY B C   1 
ATOM   3987 O O   . GLY B 2 288 ? 132.029 135.826 101.578 1.00 14.96  ? 288 GLY B O   1 
ATOM   3988 N N   . TYR B 2 289 ? 133.349 135.441 103.366 1.00 12.37  ? 289 TYR B N   1 
ATOM   3989 C CA  . TYR B 2 289 ? 133.573 134.031 103.085 1.00 12.37  ? 289 TYR B CA  1 
ATOM   3990 C C   . TYR B 2 289 ? 132.720 133.151 103.989 1.00 12.37  ? 289 TYR B C   1 
ATOM   3991 O O   . TYR B 2 289 ? 132.193 133.590 105.013 1.00 12.37  ? 289 TYR B O   1 
ATOM   3992 C CB  . TYR B 2 289 ? 135.050 133.676 103.258 1.00 12.37  ? 289 TYR B CB  1 
ATOM   3993 C CG  . TYR B 2 289 ? 135.957 134.325 102.243 1.00 12.37  ? 289 TYR B CG  1 
ATOM   3994 C CD1 . TYR B 2 289 ? 136.426 135.614 102.421 1.00 12.37  ? 289 TYR B CD1 1 
ATOM   3995 C CD2 . TYR B 2 289 ? 136.342 133.645 101.101 1.00 12.37  ? 289 TYR B CD2 1 
ATOM   3996 C CE1 . TYR B 2 289 ? 137.253 136.205 101.492 1.00 12.37  ? 289 TYR B CE1 1 
ATOM   3997 C CE2 . TYR B 2 289 ? 137.166 134.229 100.168 1.00 12.37  ? 289 TYR B CE2 1 
ATOM   3998 C CZ  . TYR B 2 289 ? 137.619 135.507 100.367 1.00 12.37  ? 289 TYR B CZ  1 
ATOM   3999 O OH  . TYR B 2 289 ? 138.443 136.090 99.434  1.00 12.37  ? 289 TYR B OH  1 
ATOM   4000 N N   . ASP B 2 290 ? 132.586 131.885 103.587 1.00 13.10  ? 290 ASP B N   1 
ATOM   4001 C CA  . ASP B 2 290 ? 131.847 130.918 104.388 1.00 13.10  ? 290 ASP B CA  1 
ATOM   4002 C C   . ASP B 2 290 ? 132.625 130.459 105.614 1.00 13.10  ? 290 ASP B C   1 
ATOM   4003 O O   . ASP B 2 290 ? 132.023 129.899 106.536 1.00 13.10  ? 290 ASP B O   1 
ATOM   4004 C CB  . ASP B 2 290 ? 131.469 129.707 103.532 1.00 13.10  ? 290 ASP B CB  1 
ATOM   4005 C CG  . ASP B 2 290 ? 130.263 129.966 102.652 1.00 13.10  ? 290 ASP B CG  1 
ATOM   4006 O OD1 . ASP B 2 290 ? 129.318 130.632 103.119 1.00 13.10  ? 290 ASP B OD1 1 
ATOM   4007 O OD2 . ASP B 2 290 ? 130.258 129.501 101.494 1.00 13.10  ? 290 ASP B OD2 1 
ATOM   4008 N N   . ASP B 2 291 ? 133.941 130.688 105.658 1.00 17.19  ? 291 ASP B N   1 
ATOM   4009 C CA  . ASP B 2 291 ? 134.736 130.371 106.839 1.00 17.19  ? 291 ASP B CA  1 
ATOM   4010 C C   . ASP B 2 291 ? 134.676 131.462 107.892 1.00 17.19  ? 291 ASP B C   1 
ATOM   4011 O O   . ASP B 2 291 ? 135.625 131.612 108.666 1.00 17.19  ? 291 ASP B O   1 
ATOM   4012 C CB  . ASP B 2 291 ? 136.197 130.100 106.463 1.00 17.19  ? 291 ASP B CB  1 
ATOM   4013 C CG  . ASP B 2 291 ? 136.936 131.347 106.025 1.00 17.19  ? 291 ASP B CG  1 
ATOM   4014 O OD1 . ASP B 2 291 ? 136.323 132.432 105.976 1.00 17.19  ? 291 ASP B OD1 1 
ATOM   4015 O OD2 . ASP B 2 291 ? 138.145 131.242 105.737 1.00 17.19  ? 291 ASP B OD2 1 
ATOM   4016 N N   . PHE B 2 292 ? 133.603 132.249 107.900 1.00 16.66  ? 292 PHE B N   1 
ATOM   4017 C CA  . PHE B 2 292 ? 133.215 133.139 108.983 1.00 16.66  ? 292 PHE B CA  1 
ATOM   4018 C C   . PHE B 2 292 ? 134.003 134.440 108.961 1.00 16.66  ? 292 PHE B C   1 
ATOM   4019 O O   . PHE B 2 292 ? 133.900 135.227 109.912 1.00 16.66  ? 292 PHE B O   1 
ATOM   4020 C CB  . PHE B 2 292 ? 133.407 132.465 110.346 1.00 16.66  ? 292 PHE B CB  1 
ATOM   4021 C CG  . PHE B 2 292 ? 132.476 131.306 110.590 1.00 16.66  ? 292 PHE B CG  1 
ATOM   4022 C CD1 . PHE B 2 292 ? 131.366 131.104 109.790 1.00 16.66  ? 292 PHE B CD1 1 
ATOM   4023 C CD2 . PHE B 2 292 ? 132.725 130.407 111.610 1.00 16.66  ? 292 PHE B CD2 1 
ATOM   4024 C CE1 . PHE B 2 292 ? 130.528 130.034 109.999 1.00 16.66  ? 292 PHE B CE1 1 
ATOM   4025 C CE2 . PHE B 2 292 ? 131.875 129.340 111.827 1.00 16.66  ? 292 PHE B CE2 1 
ATOM   4026 C CZ  . PHE B 2 292 ? 130.777 129.155 111.021 1.00 16.66  ? 292 PHE B CZ  1 
ATOM   4027 N N   . ASN B 2 293 ? 134.772 134.704 107.911 1.00 16.67  ? 293 ASN B N   1 
ATOM   4028 C CA  . ASN B 2 293 ? 135.673 135.842 107.876 1.00 16.67  ? 293 ASN B CA  1 
ATOM   4029 C C   . ASN B 2 293 ? 135.374 136.723 106.671 1.00 16.67  ? 293 ASN B C   1 
ATOM   4030 O O   . ASN B 2 293 ? 134.645 136.344 105.753 1.00 16.67  ? 293 ASN B O   1 
ATOM   4031 C CB  . ASN B 2 293 ? 137.132 135.379 107.825 1.00 16.67  ? 293 ASN B CB  1 
ATOM   4032 C CG  . ASN B 2 293 ? 137.733 135.209 109.197 1.00 16.67  ? 293 ASN B CG  1 
ATOM   4033 O OD1 . ASN B 2 293 ? 137.020 135.078 110.190 1.00 16.67  ? 293 ASN B OD1 1 
ATOM   4034 N ND2 . ASN B 2 293 ? 139.056 135.216 109.261 1.00 16.67  ? 293 ASN B ND2 1 
ATOM   4035 N N   . CYS B 2 294 ? 135.953 137.918 106.698 1.00 20.32  ? 294 CYS B N   1 
ATOM   4036 C CA  . CYS B 2 294 ? 135.980 138.818 105.558 1.00 20.32  ? 294 CYS B CA  1 
ATOM   4037 C C   . CYS B 2 294 ? 137.430 139.164 105.262 1.00 20.32  ? 294 CYS B C   1 
ATOM   4038 O O   . CYS B 2 294 ? 138.301 139.055 106.126 1.00 20.32  ? 294 CYS B O   1 
ATOM   4039 C CB  . CYS B 2 294 ? 135.178 140.098 105.816 1.00 20.32  ? 294 CYS B CB  1 
ATOM   4040 S SG  . CYS B 2 294 ? 133.471 139.835 106.336 1.00 20.32  ? 294 CYS B SG  1 
ATOM   4041 N N   . ASN B 2 295 ? 137.690 139.577 104.026 1.00 19.03  ? 295 ASN B N   1 
ATOM   4042 C CA  . ASN B 2 295 ? 139.040 139.921 103.614 1.00 19.03  ? 295 ASN B CA  1 
ATOM   4043 C C   . ASN B 2 295 ? 139.011 141.179 102.764 1.00 19.03  ? 295 ASN B C   1 
ATOM   4044 O O   . ASN B 2 295 ? 138.172 141.313 101.872 1.00 19.03  ? 295 ASN B O   1 
ATOM   4045 C CB  . ASN B 2 295 ? 139.690 138.780 102.831 1.00 19.03  ? 295 ASN B CB  1 
ATOM   4046 C CG  . ASN B 2 295 ? 140.262 137.710 103.733 1.00 19.03  ? 295 ASN B CG  1 
ATOM   4047 O OD1 . ASN B 2 295 ? 140.736 137.995 104.830 1.00 19.03  ? 295 ASN B OD1 1 
ATOM   4048 N ND2 . ASN B 2 295 ? 140.221 136.466 103.274 1.00 19.03  ? 295 ASN B ND2 1 
ATOM   4049 N N   . VAL B 2 296 ? 139.937 142.087 103.040 1.00 24.19  ? 296 VAL B N   1 
ATOM   4050 C CA  . VAL B 2 296 ? 140.059 143.344 102.312 1.00 24.19  ? 296 VAL B CA  1 
ATOM   4051 C C   . VAL B 2 296 ? 141.195 143.182 101.312 1.00 24.19  ? 296 VAL B C   1 
ATOM   4052 O O   . VAL B 2 296 ? 142.371 143.150 101.689 1.00 24.19  ? 296 VAL B O   1 
ATOM   4053 C CB  . VAL B 2 296 ? 140.305 144.522 103.262 1.00 24.19  ? 296 VAL B CB  1 
ATOM   4054 C CG1 . VAL B 2 296 ? 140.108 145.838 102.538 1.00 24.19  ? 296 VAL B CG1 1 
ATOM   4055 C CG2 . VAL B 2 296 ? 139.377 144.429 104.458 1.00 24.19  ? 296 VAL B CG2 1 
ATOM   4056 N N   . TRP B 2 297 ? 140.847 143.089 100.033 1.00 15.30  ? 297 TRP B N   1 
ATOM   4057 C CA  . TRP B 2 297 ? 141.795 142.771 98.976  1.00 15.30  ? 297 TRP B CA  1 
ATOM   4058 C C   . TRP B 2 297 ? 142.299 144.049 98.326  1.00 15.30  ? 297 TRP B C   1 
ATOM   4059 O O   . TRP B 2 297 ? 141.506 144.922 97.966  1.00 15.30  ? 297 TRP B O   1 
ATOM   4060 C CB  . TRP B 2 297 ? 141.141 141.878 97.923  1.00 15.30  ? 297 TRP B CB  1 
ATOM   4061 C CG  . TRP B 2 297 ? 140.994 140.461 98.352  1.00 15.30  ? 297 TRP B CG  1 
ATOM   4062 C CD1 . TRP B 2 297 ? 139.882 139.874 98.871  1.00 15.30  ? 297 TRP B CD1 1 
ATOM   4063 C CD2 . TRP B 2 297 ? 142.000 139.444 98.306  1.00 15.30  ? 297 TRP B CD2 1 
ATOM   4064 N NE1 . TRP B 2 297 ? 140.129 138.554 99.148  1.00 15.30  ? 297 TRP B NE1 1 
ATOM   4065 C CE2 . TRP B 2 297 ? 141.426 138.267 98.813  1.00 15.30  ? 297 TRP B CE2 1 
ATOM   4066 C CE3 . TRP B 2 297 ? 143.334 139.417 97.888  1.00 15.30  ? 297 TRP B CE3 1 
ATOM   4067 C CZ2 . TRP B 2 297 ? 142.135 137.075 98.909  1.00 15.30  ? 297 TRP B CZ2 1 
ATOM   4068 C CZ3 . TRP B 2 297 ? 144.033 138.234 97.983  1.00 15.30  ? 297 TRP B CZ3 1 
ATOM   4069 C CH2 . TRP B 2 297 ? 143.435 137.080 98.490  1.00 15.30  ? 297 TRP B CH2 1 
ATOM   4070 N N   . ASP B 2 298 ? 143.615 144.150 98.162  1.00 23.90  ? 298 ASP B N   1 
ATOM   4071 C CA  . ASP B 2 298 ? 144.201 145.297 97.485  1.00 23.90  ? 298 ASP B CA  1 
ATOM   4072 C C   . ASP B 2 298 ? 143.896 145.216 95.996  1.00 23.90  ? 298 ASP B C   1 
ATOM   4073 O O   . ASP B 2 298 ? 144.625 144.567 95.241  1.00 23.90  ? 298 ASP B O   1 
ATOM   4074 C CB  . ASP B 2 298 ? 145.708 145.347 97.730  1.00 23.90  ? 298 ASP B CB  1 
ATOM   4075 C CG  . ASP B 2 298 ? 146.346 146.596 97.169  1.00 23.90  ? 298 ASP B CG  1 
ATOM   4076 O OD1 . ASP B 2 298 ? 145.602 147.523 96.789  1.00 23.90  ? 298 ASP B OD1 1 
ATOM   4077 O OD2 . ASP B 2 298 ? 147.591 146.654 97.113  1.00 23.90  ? 298 ASP B OD2 1 
ATOM   4078 N N   . ALA B 2 299 ? 142.825 145.887 95.566  1.00 25.03  ? 299 ALA B N   1 
ATOM   4079 C CA  . ALA B 2 299 ? 142.287 145.665 94.226  1.00 25.03  ? 299 ALA B CA  1 
ATOM   4080 C C   . ALA B 2 299 ? 143.345 145.841 93.145  1.00 25.03  ? 299 ALA B C   1 
ATOM   4081 O O   . ALA B 2 299 ? 143.340 145.118 92.143  1.00 25.03  ? 299 ALA B O   1 
ATOM   4082 C CB  . ALA B 2 299 ? 141.117 146.613 93.971  1.00 25.03  ? 299 ALA B CB  1 
ATOM   4083 N N   . LEU B 2 300 ? 144.254 146.791 93.319  1.00 33.22  ? 300 LEU B N   1 
ATOM   4084 C CA  . LEU B 2 300 ? 145.230 147.107 92.286  1.00 33.22  ? 300 LEU B CA  1 
ATOM   4085 C C   . LEU B 2 300 ? 146.501 146.274 92.381  1.00 33.22  ? 300 LEU B C   1 
ATOM   4086 O O   . LEU B 2 300 ? 147.380 146.421 91.527  1.00 33.22  ? 300 LEU B O   1 
ATOM   4087 C CB  . LEU B 2 300 ? 145.583 148.596 92.336  1.00 33.22  ? 300 LEU B CB  1 
ATOM   4088 C CG  . LEU B 2 300 ? 144.681 149.502 91.491  1.00 33.22  ? 300 LEU B CG  1 
ATOM   4089 C CD1 . LEU B 2 300 ? 143.216 149.119 91.638  1.00 33.22  ? 300 LEU B CD1 1 
ATOM   4090 C CD2 . LEU B 2 300 ? 144.883 150.959 91.865  1.00 33.22  ? 300 LEU B CD2 1 
ATOM   4091 N N   . LYS B 2 301 ? 146.624 145.410 93.387  1.00 31.17  ? 301 LYS B N   1 
ATOM   4092 C CA  . LYS B 2 301 ? 147.766 144.515 93.489  1.00 31.17  ? 301 LYS B CA  1 
ATOM   4093 C C   . LYS B 2 301 ? 147.392 143.083 93.837  1.00 31.17  ? 301 LYS B C   1 
ATOM   4094 O O   . LYS B 2 301 ? 148.251 142.201 93.733  1.00 31.17  ? 301 LYS B O   1 
ATOM   4095 C CB  . LYS B 2 301 ? 148.764 145.032 94.535  1.00 31.17  ? 301 LYS B CB  1 
ATOM   4096 C CG  . LYS B 2 301 ? 149.404 146.359 94.170  1.00 31.17  ? 301 LYS B CG  1 
ATOM   4097 C CD  . LYS B 2 301 ? 150.477 146.752 95.171  1.00 31.17  ? 301 LYS B CD  1 
ATOM   4098 C CE  . LYS B 2 301 ? 151.824 146.155 94.804  1.00 31.17  ? 301 LYS B CE  1 
ATOM   4099 N NZ  . LYS B 2 301 ? 152.448 146.853 93.649  1.00 31.17  ? 301 LYS B NZ  1 
ATOM   4100 N N   . ALA B 2 302 ? 146.154 142.823 94.250  1.00 22.07  ? 302 ALA B N   1 
ATOM   4101 C CA  . ALA B 2 302 ? 145.631 141.505 94.588  1.00 22.07  ? 302 ALA B CA  1 
ATOM   4102 C C   . ALA B 2 302 ? 146.221 140.947 95.875  1.00 22.07  ? 302 ALA B C   1 
ATOM   4103 O O   . ALA B 2 302 ? 145.810 139.864 96.303  1.00 22.07  ? 302 ALA B O   1 
ATOM   4104 C CB  . ALA B 2 302 ? 145.855 140.486 93.463  1.00 22.07  ? 302 ALA B CB  1 
ATOM   4105 N N   . ASP B 2 303 ? 147.161 141.642 96.510  1.00 19.93  ? 303 ASP B N   1 
ATOM   4106 C CA  . ASP B 2 303 ? 147.701 141.197 97.785  1.00 19.93  ? 303 ASP B CA  1 
ATOM   4107 C C   . ASP B 2 303 ? 146.726 141.543 98.900  1.00 19.93  ? 303 ASP B C   1 
ATOM   4108 O O   . ASP B 2 303 ? 146.241 142.676 98.982  1.00 19.93  ? 303 ASP B O   1 
ATOM   4109 C CB  . ASP B 2 303 ? 149.057 141.848 98.049  1.00 19.93  ? 303 ASP B CB  1 
ATOM   4110 C CG  . ASP B 2 303 ? 150.024 141.664 96.901  1.00 19.93  ? 303 ASP B CG  1 
ATOM   4111 O OD1 . ASP B 2 303 ? 149.747 140.828 96.016  1.00 19.93  ? 303 ASP B OD1 1 
ATOM   4112 O OD2 . ASP B 2 303 ? 151.063 142.355 96.881  1.00 19.93  ? 303 ASP B OD2 1 
ATOM   4113 N N   . ARG B 2 304 ? 146.437 140.570 99.757  1.00 18.54  ? 304 ARG B N   1 
ATOM   4114 C CA  . ARG B 2 304 ? 145.499 140.803 100.844 1.00 18.54  ? 304 ARG B CA  1 
ATOM   4115 C C   . ARG B 2 304 ? 146.016 141.906 101.758 1.00 18.54  ? 304 ARG B C   1 
ATOM   4116 O O   . ARG B 2 304 ? 147.219 142.020 102.005 1.00 18.54  ? 304 ARG B O   1 
ATOM   4117 C CB  . ARG B 2 304 ? 145.277 139.517 101.637 1.00 18.54  ? 304 ARG B CB  1 
ATOM   4118 C CG  . ARG B 2 304 ? 144.314 139.674 102.799 1.00 18.54  ? 304 ARG B CG  1 
ATOM   4119 C CD  . ARG B 2 304 ? 143.234 138.609 102.793 1.00 18.54  ? 304 ARG B CD  1 
ATOM   4120 N NE  . ARG B 2 304 ? 143.767 137.268 102.592 1.00 18.54  ? 304 ARG B NE  1 
ATOM   4121 C CZ  . ARG B 2 304 ? 144.309 136.524 103.544 1.00 18.54  ? 304 ARG B CZ  1 
ATOM   4122 N NH1 . ARG B 2 304 ? 144.411 136.958 104.790 1.00 18.54  ? 304 ARG B NH1 1 
ATOM   4123 N NH2 . ARG B 2 304 ? 144.763 135.310 103.241 1.00 18.54  ? 304 ARG B NH2 1 
ATOM   4124 N N   . ALA B 2 305 ? 145.095 142.733 102.252 1.00 20.31  ? 305 ALA B N   1 
ATOM   4125 C CA  . ALA B 2 305 ? 145.434 143.835 103.144 1.00 20.31  ? 305 ALA B CA  1 
ATOM   4126 C C   . ALA B 2 305 ? 145.167 143.483 104.604 1.00 20.31  ? 305 ALA B C   1 
ATOM   4127 O O   . ALA B 2 305 ? 146.072 143.554 105.438 1.00 20.31  ? 305 ALA B O   1 
ATOM   4128 C CB  . ALA B 2 305 ? 144.650 145.091 102.745 1.00 20.31  ? 305 ALA B CB  1 
ATOM   4129 N N   . GLY B 2 306 ? 143.935 143.097 104.926 1.00 18.90  ? 306 GLY B N   1 
ATOM   4130 C CA  . GLY B 2 306 ? 143.585 142.773 106.294 1.00 18.90  ? 306 GLY B CA  1 
ATOM   4131 C C   . GLY B 2 306 ? 142.438 141.793 106.395 1.00 18.90  ? 306 GLY B C   1 
ATOM   4132 O O   . GLY B 2 306 ? 142.022 141.211 105.393 1.00 18.90  ? 306 GLY B O   1 
ATOM   4133 N N   . VAL B 2 307 ? 141.922 141.598 107.605 1.00 16.69  ? 307 VAL B N   1 
ATOM   4134 C CA  . VAL B 2 307 ? 140.830 140.665 107.860 1.00 16.69  ? 307 VAL B CA  1 
ATOM   4135 C C   . VAL B 2 307 ? 139.911 141.274 108.906 1.00 16.69  ? 307 VAL B C   1 
ATOM   4136 O O   . VAL B 2 307 ? 140.372 141.949 109.832 1.00 16.69  ? 307 VAL B O   1 
ATOM   4137 C CB  . VAL B 2 307 ? 141.354 139.297 108.334 1.00 16.69  ? 307 VAL B CB  1 
ATOM   4138 C CG1 . VAL B 2 307 ? 140.243 138.259 108.305 1.00 16.69  ? 307 VAL B CG1 1 
ATOM   4139 C CG2 . VAL B 2 307 ? 142.527 138.850 107.483 1.00 16.69  ? 307 VAL B CG2 1 
ATOM   4140 N N   . LEU B 2 308 ? 138.611 141.037 108.760 1.00 18.16  ? 308 LEU B N   1 
ATOM   4141 C CA  . LEU B 2 308 ? 137.607 141.473 109.729 1.00 18.16  ? 308 LEU B CA  1 
ATOM   4142 C C   . LEU B 2 308 ? 137.059 140.223 110.411 1.00 18.16  ? 308 LEU B C   1 
ATOM   4143 O O   . LEU B 2 308 ? 136.039 139.669 110.000 1.00 18.16  ? 308 LEU B O   1 
ATOM   4144 C CB  . LEU B 2 308 ? 136.492 142.273 109.061 1.00 18.16  ? 308 LEU B CB  1 
ATOM   4145 C CG  . LEU B 2 308 ? 136.894 143.435 108.151 1.00 18.16  ? 308 LEU B CG  1 
ATOM   4146 C CD1 . LEU B 2 308 ? 135.687 144.317 107.890 1.00 18.16  ? 308 LEU B CD1 1 
ATOM   4147 C CD2 . LEU B 2 308 ? 138.023 144.251 108.753 1.00 18.16  ? 308 LEU B CD2 1 
ATOM   4148 N N   . ALA B 2 309 ? 137.741 139.789 111.464 1.00 26.50  ? 309 ALA B N   1 
ATOM   4149 C CA  . ALA B 2 309 ? 137.340 138.610 112.214 1.00 26.50  ? 309 ALA B CA  1 
ATOM   4150 C C   . ALA B 2 309 ? 136.507 139.010 113.422 1.00 26.50  ? 309 ALA B C   1 
ATOM   4151 O O   . ALA B 2 309 ? 136.710 140.072 114.016 1.00 26.50  ? 309 ALA B O   1 
ATOM   4152 C CB  . ALA B 2 309 ? 138.566 137.817 112.666 1.00 26.50  ? 309 ALA B CB  1 
ATOM   4153 N N   . GLY B 2 310 ? 135.568 138.144 113.790 1.00 26.34  ? 310 GLY B N   1 
ATOM   4154 C CA  . GLY B 2 310 ? 134.706 138.424 114.920 1.00 26.34  ? 310 GLY B CA  1 
ATOM   4155 C C   . GLY B 2 310 ? 133.288 137.918 114.766 1.00 26.34  ? 310 GLY B C   1 
ATOM   4156 O O   . GLY B 2 310 ? 132.504 137.976 115.716 1.00 26.34  ? 310 GLY B O   1 
ATOM   4157 N N   . HIS B 2 311 ? 132.936 137.428 113.582 1.00 17.97  ? 311 HIS B N   1 
ATOM   4158 C CA  . HIS B 2 311 ? 131.619 136.851 113.364 1.00 17.97  ? 311 HIS B CA  1 
ATOM   4159 C C   . HIS B 2 311 ? 131.638 135.385 113.763 1.00 17.97  ? 311 HIS B C   1 
ATOM   4160 O O   . HIS B 2 311 ? 132.567 134.647 113.422 1.00 17.97  ? 311 HIS B O   1 
ATOM   4161 C CB  . HIS B 2 311 ? 131.195 137.003 111.903 1.00 17.97  ? 311 HIS B CB  1 
ATOM   4162 C CG  . HIS B 2 311 ? 130.383 138.233 111.642 1.00 17.97  ? 311 HIS B CG  1 
ATOM   4163 N ND1 . HIS B 2 311 ? 129.133 138.431 112.188 1.00 17.97  ? 311 HIS B ND1 1 
ATOM   4164 C CD2 . HIS B 2 311 ? 130.646 139.333 110.898 1.00 17.97  ? 311 HIS B CD2 1 
ATOM   4165 C CE1 . HIS B 2 311 ? 128.660 139.597 111.790 1.00 17.97  ? 311 HIS B CE1 1 
ATOM   4166 N NE2 . HIS B 2 311 ? 129.558 140.164 111.006 1.00 17.97  ? 311 HIS B NE2 1 
ATOM   4167 N N   . ASP B 2 312 ? 130.609 134.969 114.497 1.00 23.44  ? 312 ASP B N   1 
ATOM   4168 C CA  . ASP B 2 312 ? 130.538 133.615 115.027 1.00 23.44  ? 312 ASP B CA  1 
ATOM   4169 C C   . ASP B 2 312 ? 129.905 132.632 114.055 1.00 23.44  ? 312 ASP B C   1 
ATOM   4170 O O   . ASP B 2 312 ? 129.876 131.433 114.347 1.00 23.44  ? 312 ASP B O   1 
ATOM   4171 C CB  . ASP B 2 312 ? 129.755 133.599 116.345 1.00 23.44  ? 312 ASP B CB  1 
ATOM   4172 C CG  . ASP B 2 312 ? 130.349 134.525 117.391 1.00 23.44  ? 312 ASP B CG  1 
ATOM   4173 O OD1 . ASP B 2 312 ? 131.564 134.426 117.661 1.00 23.44  ? 312 ASP B OD1 1 
ATOM   4174 O OD2 . ASP B 2 312 ? 129.598 135.348 117.954 1.00 23.44  ? 312 ASP B OD2 1 
ATOM   4175 N N   . ASN B 2 313 ? 129.410 133.101 112.913 1.00 18.71  ? 313 ASN B N   1 
ATOM   4176 C CA  . ASN B 2 313 ? 128.803 132.221 111.931 1.00 18.71  ? 313 ASN B CA  1 
ATOM   4177 C C   . ASN B 2 313 ? 128.927 132.858 110.552 1.00 18.71  ? 313 ASN B C   1 
ATOM   4178 O O   . ASN B 2 313 ? 129.466 133.956 110.397 1.00 18.71  ? 313 ASN B O   1 
ATOM   4179 C CB  . ASN B 2 313 ? 127.345 131.927 112.290 1.00 18.71  ? 313 ASN B CB  1 
ATOM   4180 C CG  . ASN B 2 313 ? 126.876 130.600 111.734 1.00 18.71  ? 313 ASN B CG  1 
ATOM   4181 O OD1 . ASN B 2 313 ? 127.254 130.218 110.632 1.00 18.71  ? 313 ASN B OD1 1 
ATOM   4182 N ND2 . ASN B 2 313 ? 126.070 129.882 112.501 1.00 18.71  ? 313 ASN B ND2 1 
ATOM   4183 N N   . ARG B 2 314 ? 128.422 132.149 109.545 1.00 12.16  ? 314 ARG B N   1 
ATOM   4184 C CA  . ARG B 2 314 ? 128.580 132.536 108.149 1.00 12.16  ? 314 ARG B CA  1 
ATOM   4185 C C   . ARG B 2 314 ? 128.227 133.999 107.912 1.00 12.16  ? 314 ARG B C   1 
ATOM   4186 O O   . ARG B 2 314 ? 127.342 134.548 108.574 1.00 12.16  ? 314 ARG B O   1 
ATOM   4187 C CB  . ARG B 2 314 ? 127.708 131.641 107.271 1.00 12.16  ? 314 ARG B CB  1 
ATOM   4188 C CG  . ARG B 2 314 ? 127.883 131.854 105.780 1.00 12.16  ? 314 ARG B CG  1 
ATOM   4189 C CD  . ARG B 2 314 ? 126.793 131.158 105.003 1.00 12.16  ? 314 ARG B CD  1 
ATOM   4190 N NE  . ARG B 2 314 ? 127.067 131.141 103.574 1.00 12.16  ? 314 ARG B NE  1 
ATOM   4191 C CZ  . ARG B 2 314 ? 126.369 130.438 102.694 1.00 12.16  ? 314 ARG B CZ  1 
ATOM   4192 N NH1 . ARG B 2 314 ? 125.351 129.682 103.066 1.00 12.16  ? 314 ARG B NH1 1 
ATOM   4193 N NH2 . ARG B 2 314 ? 126.708 130.485 101.410 1.00 12.16  ? 314 ARG B NH2 1 
ATOM   4194 N N   . VAL B 2 315 ? 128.914 134.632 106.966 1.00 11.47  ? 315 VAL B N   1 
ATOM   4195 C CA  . VAL B 2 315 ? 128.625 135.999 106.548 1.00 11.47  ? 315 VAL B CA  1 
ATOM   4196 C C   . VAL B 2 315 ? 127.794 135.925 105.276 1.00 11.47  ? 315 VAL B C   1 
ATOM   4197 O O   . VAL B 2 315 ? 128.258 135.411 104.252 1.00 11.47  ? 315 VAL B O   1 
ATOM   4198 C CB  . VAL B 2 315 ? 129.914 136.799 106.311 1.00 11.47  ? 315 VAL B CB  1 
ATOM   4199 C CG1 . VAL B 2 315 ? 129.596 138.270 106.137 1.00 11.47  ? 315 VAL B CG1 1 
ATOM   4200 C CG2 . VAL B 2 315 ? 130.880 136.594 107.455 1.00 11.47  ? 315 VAL B CG2 1 
ATOM   4201 N N   . SER B 2 316 ? 126.568 136.450 105.332 1.00 9.80   ? 316 SER B N   1 
ATOM   4202 C CA  . SER B 2 316 ? 125.627 136.325 104.231 1.00 9.80   ? 316 SER B CA  1 
ATOM   4203 C C   . SER B 2 316 ? 125.347 137.628 103.503 1.00 9.80   ? 316 SER B C   1 
ATOM   4204 O O   . SER B 2 316 ? 124.844 137.587 102.377 1.00 9.80   ? 316 SER B O   1 
ATOM   4205 C CB  . SER B 2 316 ? 124.296 135.754 104.739 1.00 9.80   ? 316 SER B CB  1 
ATOM   4206 O OG  . SER B 2 316 ? 123.789 136.529 105.807 1.00 9.80   ? 316 SER B OG  1 
ATOM   4207 N N   . CYS B 2 317 ? 125.654 138.774 104.105 1.00 14.52  ? 317 CYS B N   1 
ATOM   4208 C CA  . CYS B 2 317 ? 125.373 140.057 103.485 1.00 14.52  ? 317 CYS B CA  1 
ATOM   4209 C C   . CYS B 2 317 ? 126.438 141.053 103.906 1.00 14.52  ? 317 CYS B C   1 
ATOM   4210 O O   . CYS B 2 317 ? 127.126 140.869 104.911 1.00 14.52  ? 317 CYS B O   1 
ATOM   4211 C CB  . CYS B 2 317 ? 123.978 140.558 103.863 1.00 14.52  ? 317 CYS B CB  1 
ATOM   4212 S SG  . CYS B 2 317 ? 123.780 140.904 105.615 1.00 14.52  ? 317 CYS B SG  1 
ATOM   4213 N N   . LEU B 2 318 ? 126.572 142.115 103.118 1.00 21.07  ? 318 LEU B N   1 
ATOM   4214 C CA  . LEU B 2 318 ? 127.637 143.085 103.328 1.00 21.07  ? 318 LEU B CA  1 
ATOM   4215 C C   . LEU B 2 318 ? 127.367 144.349 102.523 1.00 21.07  ? 318 LEU B C   1 
ATOM   4216 O O   . LEU B 2 318 ? 127.109 144.278 101.318 1.00 21.07  ? 318 LEU B O   1 
ATOM   4217 C CB  . LEU B 2 318 ? 128.982 142.464 102.941 1.00 21.07  ? 318 LEU B CB  1 
ATOM   4218 C CG  . LEU B 2 318 ? 130.219 143.359 102.947 1.00 21.07  ? 318 LEU B CG  1 
ATOM   4219 C CD1 . LEU B 2 318 ? 131.401 142.601 103.506 1.00 21.07  ? 318 LEU B CD1 1 
ATOM   4220 C CD2 . LEU B 2 318 ? 130.524 143.854 101.552 1.00 21.07  ? 318 LEU B CD2 1 
ATOM   4221 N N   . GLY B 2 319 ? 127.424 145.508 103.171 1.00 15.51  ? 319 GLY B N   1 
ATOM   4222 C CA  . GLY B 2 319 ? 127.136 146.758 102.494 1.00 15.51  ? 319 GLY B CA  1 
ATOM   4223 C C   . GLY B 2 319 ? 127.976 147.885 103.050 1.00 15.51  ? 319 GLY B C   1 
ATOM   4224 O O   . GLY B 2 319 ? 128.418 147.853 104.202 1.00 15.51  ? 319 GLY B O   1 
ATOM   4225 N N   . VAL B 2 320 ? 128.189 148.894 102.211 1.00 16.28  ? 320 VAL B N   1 
ATOM   4226 C CA  . VAL B 2 320 ? 128.989 150.061 102.558 1.00 16.28  ? 320 VAL B CA  1 
ATOM   4227 C C   . VAL B 2 320 ? 128.148 151.306 102.313 1.00 16.28  ? 320 VAL B C   1 
ATOM   4228 O O   . VAL B 2 320 ? 127.510 151.431 101.263 1.00 16.28  ? 320 VAL B O   1 
ATOM   4229 C CB  . VAL B 2 320 ? 130.297 150.120 101.745 1.00 16.28  ? 320 VAL B CB  1 
ATOM   4230 C CG1 . VAL B 2 320 ? 131.067 151.390 102.063 1.00 16.28  ? 320 VAL B CG1 1 
ATOM   4231 C CG2 . VAL B 2 320 ? 131.145 148.890 102.022 1.00 16.28  ? 320 VAL B CG2 1 
ATOM   4232 N N   . THR B 2 321 ? 128.147 152.218 103.281 1.00 15.54  ? 321 THR B N   1 
ATOM   4233 C CA  . THR B 2 321 ? 127.346 153.427 103.180 1.00 15.54  ? 321 THR B CA  1 
ATOM   4234 C C   . THR B 2 321 ? 127.707 154.214 101.925 1.00 15.54  ? 321 THR B C   1 
ATOM   4235 O O   . THR B 2 321 ? 128.775 154.044 101.336 1.00 15.54  ? 321 THR B O   1 
ATOM   4236 C CB  . THR B 2 321 ? 127.558 154.308 104.408 1.00 15.54  ? 321 THR B CB  1 
ATOM   4237 O OG1 . THR B 2 321 ? 128.960 154.490 104.626 1.00 15.54  ? 321 THR B OG1 1 
ATOM   4238 C CG2 . THR B 2 321 ? 126.951 153.670 105.634 1.00 15.54  ? 321 THR B CG2 1 
ATOM   4239 N N   . ASP B 2 322 ? 126.790 155.096 101.522 1.00 18.37  ? 322 ASP B N   1 
ATOM   4240 C CA  . ASP B 2 322 ? 127.034 155.930 100.349 1.00 18.37  ? 322 ASP B CA  1 
ATOM   4241 C C   . ASP B 2 322 ? 128.246 156.827 100.553 1.00 18.37  ? 322 ASP B C   1 
ATOM   4242 O O   . ASP B 2 322 ? 129.075 156.977 99.649  1.00 18.37  ? 322 ASP B O   1 
ATOM   4243 C CB  . ASP B 2 322 ? 125.800 156.774 100.037 1.00 18.37  ? 322 ASP B CB  1 
ATOM   4244 C CG  . ASP B 2 322 ? 124.672 155.962 99.441  1.00 18.37  ? 322 ASP B CG  1 
ATOM   4245 O OD1 . ASP B 2 322 ? 124.861 154.749 99.218  1.00 18.37  ? 322 ASP B OD1 1 
ATOM   4246 O OD2 . ASP B 2 322 ? 123.596 156.541 99.187  1.00 18.37  ? 322 ASP B OD2 1 
ATOM   4247 N N   . ASP B 2 323 ? 128.367 157.433 101.732 1.00 19.12  ? 323 ASP B N   1 
ATOM   4248 C CA  . ASP B 2 323 ? 129.473 158.336 102.021 1.00 19.12  ? 323 ASP B CA  1 
ATOM   4249 C C   . ASP B 2 323 ? 130.733 157.607 102.468 1.00 19.12  ? 323 ASP B C   1 
ATOM   4250 O O   . ASP B 2 323 ? 131.729 158.264 102.781 1.00 19.12  ? 323 ASP B O   1 
ATOM   4251 C CB  . ASP B 2 323 ? 129.066 159.355 103.090 1.00 19.12  ? 323 ASP B CB  1 
ATOM   4252 C CG  . ASP B 2 323 ? 128.356 158.720 104.266 1.00 19.12  ? 323 ASP B CG  1 
ATOM   4253 O OD1 . ASP B 2 323 ? 127.991 157.532 104.169 1.00 19.12  ? 323 ASP B OD1 1 
ATOM   4254 O OD2 . ASP B 2 323 ? 128.158 159.410 105.287 1.00 19.12  ? 323 ASP B OD2 1 
ATOM   4255 N N   . GLY B 2 324 ? 130.716 156.279 102.507 1.00 21.74  ? 324 GLY B N   1 
ATOM   4256 C CA  . GLY B 2 324 ? 131.903 155.523 102.866 1.00 21.74  ? 324 GLY B CA  1 
ATOM   4257 C C   . GLY B 2 324 ? 132.344 155.716 104.298 1.00 21.74  ? 324 GLY B C   1 
ATOM   4258 O O   . GLY B 2 324 ? 133.550 155.765 104.570 1.00 21.74  ? 324 GLY B O   1 
ATOM   4259 N N   . MET B 2 325 ? 131.395 155.829 105.225 1.00 23.07  ? 325 MET B N   1 
ATOM   4260 C CA  . MET B 2 325 ? 131.715 156.009 106.634 1.00 23.07  ? 325 MET B CA  1 
ATOM   4261 C C   . MET B 2 325 ? 131.734 154.703 107.411 1.00 23.07  ? 325 MET B C   1 
ATOM   4262 O O   . MET B 2 325 ? 132.520 154.570 108.355 1.00 23.07  ? 325 MET B O   1 
ATOM   4263 C CB  . MET B 2 325 ? 130.704 156.956 107.286 1.00 23.07  ? 325 MET B CB  1 
ATOM   4264 C CG  . MET B 2 325 ? 131.100 158.417 107.248 1.00 23.07  ? 325 MET B CG  1 
ATOM   4265 S SD  . MET B 2 325 ? 132.585 158.767 108.206 1.00 23.07  ? 325 MET B SD  1 
ATOM   4266 C CE  . MET B 2 325 ? 133.226 160.184 107.323 1.00 23.07  ? 325 MET B CE  1 
ATOM   4267 N N   . ALA B 2 326 ? 130.897 153.735 107.044 1.00 17.56  ? 326 ALA B N   1 
ATOM   4268 C CA  . ALA B 2 326 ? 130.745 152.525 107.835 1.00 17.56  ? 326 ALA B CA  1 
ATOM   4269 C C   . ALA B 2 326 ? 130.499 151.327 106.933 1.00 17.56  ? 326 ALA B C   1 
ATOM   4270 O O   . ALA B 2 326 ? 130.008 151.460 105.811 1.00 17.56  ? 326 ALA B O   1 
ATOM   4271 C CB  . ALA B 2 326 ? 129.591 152.654 108.830 1.00 17.56  ? 326 ALA B CB  1 
ATOM   4272 N N   . VAL B 2 327 ? 130.848 150.152 107.447 1.00 16.45  ? 327 VAL B N   1 
ATOM   4273 C CA  . VAL B 2 327 ? 130.622 148.875 106.783 1.00 16.45  ? 327 VAL B CA  1 
ATOM   4274 C C   . VAL B 2 327 ? 129.788 148.020 107.722 1.00 16.45  ? 327 VAL B C   1 
ATOM   4275 O O   . VAL B 2 327 ? 130.181 147.793 108.872 1.00 16.45  ? 327 VAL B O   1 
ATOM   4276 C CB  . VAL B 2 327 ? 131.939 148.165 106.435 1.00 16.45  ? 327 VAL B CB  1 
ATOM   4277 C CG1 . VAL B 2 327 ? 131.666 146.859 105.711 1.00 16.45  ? 327 VAL B CG1 1 
ATOM   4278 C CG2 . VAL B 2 327 ? 132.828 149.069 105.601 1.00 16.45  ? 327 VAL B CG2 1 
ATOM   4279 N N   . ALA B 2 328 ? 128.644 147.553 107.243 1.00 13.26  ? 328 ALA B N   1 
ATOM   4280 C CA  . ALA B 2 328 ? 127.777 146.671 108.007 1.00 13.26  ? 328 ALA B CA  1 
ATOM   4281 C C   . ALA B 2 328 ? 127.839 145.274 107.414 1.00 13.26  ? 328 ALA B C   1 
ATOM   4282 O O   . ALA B 2 328 ? 127.884 145.113 106.192 1.00 13.26  ? 328 ALA B O   1 
ATOM   4283 C CB  . ALA B 2 328 ? 126.335 147.175 108.006 1.00 13.26  ? 328 ALA B CB  1 
ATOM   4284 N N   . THR B 2 329 ? 127.851 144.266 108.283 1.00 13.79  ? 329 THR B N   1 
ATOM   4285 C CA  . THR B 2 329 ? 127.947 142.872 107.851 1.00 13.79  ? 329 THR B CA  1 
ATOM   4286 C C   . THR B 2 329 ? 127.000 142.043 108.709 1.00 13.79  ? 329 THR B C   1 
ATOM   4287 O O   . THR B 2 329 ? 127.312 141.730 109.860 1.00 13.79  ? 329 THR B O   1 
ATOM   4288 C CB  . THR B 2 329 ? 129.377 142.349 107.956 1.00 13.79  ? 329 THR B CB  1 
ATOM   4289 O OG1 . THR B 2 329 ? 129.740 142.212 109.333 1.00 13.79  ? 329 THR B OG1 1 
ATOM   4290 C CG2 . THR B 2 329 ? 130.350 143.290 107.272 1.00 13.79  ? 329 THR B CG2 1 
ATOM   4291 N N   . GLY B 2 330 ? 125.852 141.692 108.149 1.00 10.95  ? 330 GLY B N   1 
ATOM   4292 C CA  . GLY B 2 330 ? 124.997 140.715 108.782 1.00 10.95  ? 330 GLY B CA  1 
ATOM   4293 C C   . GLY B 2 330 ? 125.601 139.331 108.688 1.00 10.95  ? 330 GLY B C   1 
ATOM   4294 O O   . GLY B 2 330 ? 126.526 139.070 107.921 1.00 10.95  ? 330 GLY B O   1 
ATOM   4295 N N   . SER B 2 331 ? 125.067 138.423 109.492 1.00 9.57   ? 331 SER B N   1 
ATOM   4296 C CA  . SER B 2 331 ? 125.629 137.083 109.573 1.00 9.57   ? 331 SER B CA  1 
ATOM   4297 C C   . SER B 2 331 ? 124.544 136.121 110.023 1.00 9.57   ? 331 SER B C   1 
ATOM   4298 O O   . SER B 2 331 ? 123.475 136.525 110.481 1.00 9.57   ? 331 SER B O   1 
ATOM   4299 C CB  . SER B 2 331 ? 126.826 137.042 110.523 1.00 9.57   ? 331 SER B CB  1 
ATOM   4300 O OG  . SER B 2 331 ? 127.089 135.717 110.944 1.00 9.57   ? 331 SER B OG  1 
ATOM   4301 N N   . TRP B 2 332 ? 124.839 134.829 109.883 1.00 12.78  ? 332 TRP B N   1 
ATOM   4302 C CA  . TRP B 2 332 ? 123.876 133.801 110.244 1.00 12.78  ? 332 TRP B CA  1 
ATOM   4303 C C   . TRP B 2 332 ? 123.706 133.655 111.748 1.00 12.78  ? 332 TRP B C   1 
ATOM   4304 O O   . TRP B 2 332 ? 122.823 132.907 112.182 1.00 12.78  ? 332 TRP B O   1 
ATOM   4305 C CB  . TRP B 2 332 ? 124.288 132.462 109.631 1.00 12.78  ? 332 TRP B CB  1 
ATOM   4306 C CG  . TRP B 2 332 ? 123.893 132.324 108.194 1.00 12.78  ? 332 TRP B CG  1 
ATOM   4307 C CD1 . TRP B 2 332 ? 123.659 133.333 107.309 1.00 12.78  ? 332 TRP B CD1 1 
ATOM   4308 C CD2 . TRP B 2 332 ? 123.681 131.104 107.475 1.00 12.78  ? 332 TRP B CD2 1 
ATOM   4309 N NE1 . TRP B 2 332 ? 123.315 132.819 106.084 1.00 12.78  ? 332 TRP B NE1 1 
ATOM   4310 C CE2 . TRP B 2 332 ? 123.322 131.452 106.160 1.00 12.78  ? 332 TRP B CE2 1 
ATOM   4311 C CE3 . TRP B 2 332 ? 123.759 129.752 107.815 1.00 12.78  ? 332 TRP B CE3 1 
ATOM   4312 C CZ2 . TRP B 2 332 ? 123.042 130.499 105.186 1.00 12.78  ? 332 TRP B CZ2 1 
ATOM   4313 C CZ3 . TRP B 2 332 ? 123.482 128.808 106.847 1.00 12.78  ? 332 TRP B CZ3 1 
ATOM   4314 C CH2 . TRP B 2 332 ? 123.128 129.185 105.549 1.00 12.78  ? 332 TRP B CH2 1 
ATOM   4315 N N   . ASP B 2 333 ? 124.518 134.340 112.549 1.00 19.32  ? 333 ASP B N   1 
ATOM   4316 C CA  . ASP B 2 333 ? 124.353 134.351 113.995 1.00 19.32  ? 333 ASP B CA  1 
ATOM   4317 C C   . ASP B 2 333 ? 123.321 135.370 114.459 1.00 19.32  ? 333 ASP B C   1 
ATOM   4318 O O   . ASP B 2 333 ? 123.101 135.502 115.666 1.00 19.32  ? 333 ASP B O   1 
ATOM   4319 C CB  . ASP B 2 333 ? 125.693 134.629 114.680 1.00 19.32  ? 333 ASP B CB  1 
ATOM   4320 C CG  . ASP B 2 333 ? 126.340 135.901 114.190 1.00 19.32  ? 333 ASP B CG  1 
ATOM   4321 O OD1 . ASP B 2 333 ? 125.799 136.513 113.250 1.00 19.32  ? 333 ASP B OD1 1 
ATOM   4322 O OD2 . ASP B 2 333 ? 127.386 136.294 114.746 1.00 19.32  ? 333 ASP B OD2 1 
ATOM   4323 N N   . SER B 2 334 ? 122.687 136.091 113.533 1.00 18.02  ? 334 SER B N   1 
ATOM   4324 C CA  . SER B 2 334 ? 121.621 137.035 113.851 1.00 18.02  ? 334 SER B CA  1 
ATOM   4325 C C   . SER B 2 334 ? 122.147 138.322 114.476 1.00 18.02  ? 334 SER B C   1 
ATOM   4326 O O   . SER B 2 334 ? 121.474 138.932 115.307 1.00 18.02  ? 334 SER B O   1 
ATOM   4327 C CB  . SER B 2 334 ? 120.578 136.398 114.772 1.00 18.02  ? 334 SER B CB  1 
ATOM   4328 O OG  . SER B 2 334 ? 120.930 136.580 116.130 1.00 18.02  ? 334 SER B OG  1 
ATOM   4329 N N   . PHE B 2 335 ? 123.347 138.748 114.089 1.00 15.51  ? 335 PHE B N   1 
ATOM   4330 C CA  . PHE B 2 335 ? 123.915 140.003 114.554 1.00 15.51  ? 335 PHE B CA  1 
ATOM   4331 C C   . PHE B 2 335 ? 124.347 140.843 113.363 1.00 15.51  ? 335 PHE B C   1 
ATOM   4332 O O   . PHE B 2 335 ? 124.624 140.328 112.279 1.00 15.51  ? 335 PHE B O   1 
ATOM   4333 C CB  . PHE B 2 335 ? 125.120 139.779 115.477 1.00 15.51  ? 335 PHE B CB  1 
ATOM   4334 C CG  . PHE B 2 335 ? 124.762 139.204 116.813 1.00 15.51  ? 335 PHE B CG  1 
ATOM   4335 C CD1 . PHE B 2 335 ? 123.838 139.830 117.626 1.00 15.51  ? 335 PHE B CD1 1 
ATOM   4336 C CD2 . PHE B 2 335 ? 125.353 138.038 117.257 1.00 15.51  ? 335 PHE B CD2 1 
ATOM   4337 C CE1 . PHE B 2 335 ? 123.509 139.301 118.851 1.00 15.51  ? 335 PHE B CE1 1 
ATOM   4338 C CE2 . PHE B 2 335 ? 125.028 137.505 118.481 1.00 15.51  ? 335 PHE B CE2 1 
ATOM   4339 C CZ  . PHE B 2 335 ? 124.103 138.138 119.279 1.00 15.51  ? 335 PHE B CZ  1 
ATOM   4340 N N   . LEU B 2 336 ? 124.393 142.152 113.581 1.00 12.70  ? 336 LEU B N   1 
ATOM   4341 C CA  . LEU B 2 336 ? 124.961 143.099 112.635 1.00 12.70  ? 336 LEU B CA  1 
ATOM   4342 C C   . LEU B 2 336 ? 126.055 143.881 113.339 1.00 12.70  ? 336 LEU B C   1 
ATOM   4343 O O   . LEU B 2 336 ? 125.883 144.308 114.482 1.00 12.70  ? 336 LEU B O   1 
ATOM   4344 C CB  . LEU B 2 336 ? 123.905 144.064 112.093 1.00 12.70  ? 336 LEU B CB  1 
ATOM   4345 C CG  . LEU B 2 336 ? 122.828 143.478 111.183 1.00 12.70  ? 336 LEU B CG  1 
ATOM   4346 C CD1 . LEU B 2 336 ? 121.598 143.118 111.989 1.00 12.70  ? 336 LEU B CD1 1 
ATOM   4347 C CD2 . LEU B 2 336 ? 122.477 144.452 110.078 1.00 12.70  ? 336 LEU B CD2 1 
ATOM   4348 N N   . LYS B 2 337 ? 127.180 144.069 112.658 1.00 15.15  ? 337 LYS B N   1 
ATOM   4349 C CA  . LYS B 2 337 ? 128.325 144.755 113.234 1.00 15.15  ? 337 LYS B CA  1 
ATOM   4350 C C   . LYS B 2 337 ? 128.750 145.882 112.310 1.00 15.15  ? 337 LYS B C   1 
ATOM   4351 O O   . LYS B 2 337 ? 128.969 145.660 111.116 1.00 15.15  ? 337 LYS B O   1 
ATOM   4352 C CB  . LYS B 2 337 ? 129.487 143.787 113.462 1.00 15.15  ? 337 LYS B CB  1 
ATOM   4353 C CG  . LYS B 2 337 ? 129.230 142.779 114.565 1.00 15.15  ? 337 LYS B CG  1 
ATOM   4354 C CD  . LYS B 2 337 ? 130.424 141.871 114.778 1.00 15.15  ? 337 LYS B CD  1 
ATOM   4355 C CE  . LYS B 2 337 ? 130.155 140.853 115.868 1.00 15.15  ? 337 LYS B CE  1 
ATOM   4356 N NZ  . LYS B 2 337 ? 130.174 141.473 117.217 1.00 15.15  ? 337 LYS B NZ  1 
ATOM   4357 N N   . ILE B 2 338 ? 128.867 147.084 112.864 1.00 14.80  ? 338 ILE B N   1 
ATOM   4358 C CA  . ILE B 2 338 ? 129.303 148.260 112.125 1.00 14.80  ? 338 ILE B CA  1 
ATOM   4359 C C   . ILE B 2 338 ? 130.785 148.463 112.398 1.00 14.80  ? 338 ILE B C   1 
ATOM   4360 O O   . ILE B 2 338 ? 131.205 148.521 113.559 1.00 14.80  ? 338 ILE B O   1 
ATOM   4361 C CB  . ILE B 2 338 ? 128.494 149.504 112.527 1.00 14.80  ? 338 ILE B CB  1 
ATOM   4362 C CG1 . ILE B 2 338 ? 127.005 149.167 112.665 1.00 14.80  ? 338 ILE B CG1 1 
ATOM   4363 C CG2 . ILE B 2 338 ? 128.687 150.606 111.515 1.00 14.80  ? 338 ILE B CG2 1 
ATOM   4364 C CD1 . ILE B 2 338 ? 126.353 148.701 111.389 1.00 14.80  ? 338 ILE B CD1 1 
ATOM   4365 N N   . TRP B 2 339 ? 131.578 148.571 111.337 1.00 14.28  ? 339 TRP B N   1 
ATOM   4366 C CA  . TRP B 2 339 ? 133.027 148.641 111.441 1.00 14.28  ? 339 TRP B CA  1 
ATOM   4367 C C   . TRP B 2 339 ? 133.531 149.963 110.881 1.00 14.28  ? 339 TRP B C   1 
ATOM   4368 O O   . TRP B 2 339 ? 132.979 150.490 109.913 1.00 14.28  ? 339 TRP B O   1 
ATOM   4369 C CB  . TRP B 2 339 ? 133.696 147.485 110.690 1.00 14.28  ? 339 TRP B CB  1 
ATOM   4370 C CG  . TRP B 2 339 ? 133.069 146.141 110.919 1.00 14.28  ? 339 TRP B CG  1 
ATOM   4371 C CD1 . TRP B 2 339 ? 131.833 145.733 110.519 1.00 14.28  ? 339 TRP B CD1 1 
ATOM   4372 C CD2 . TRP B 2 339 ? 133.660 145.021 111.590 1.00 14.28  ? 339 TRP B CD2 1 
ATOM   4373 N NE1 . TRP B 2 339 ? 131.612 144.436 110.904 1.00 14.28  ? 339 TRP B NE1 1 
ATOM   4374 C CE2 . TRP B 2 339 ? 132.719 143.975 111.564 1.00 14.28  ? 339 TRP B CE2 1 
ATOM   4375 C CE3 . TRP B 2 339 ? 134.890 144.804 112.214 1.00 14.28  ? 339 TRP B CE3 1 
ATOM   4376 C CZ2 . TRP B 2 339 ? 132.968 142.734 112.137 1.00 14.28  ? 339 TRP B CZ2 1 
ATOM   4377 C CZ3 . TRP B 2 339 ? 135.135 143.571 112.782 1.00 14.28  ? 339 TRP B CZ3 1 
ATOM   4378 C CH2 . TRP B 2 339 ? 134.180 142.552 112.739 1.00 14.28  ? 339 TRP B CH2 1 
ATOM   4379 N N   . ASN B 2 340 ? 134.583 150.492 111.499 1.00 19.50  ? 340 ASN B N   1 
ATOM   4380 C CA  . ASN B 2 340 ? 135.266 151.681 110.999 1.00 19.50  ? 340 ASN B CA  1 
ATOM   4381 C C   . ASN B 2 340 ? 136.770 151.443 110.955 1.00 19.50  ? 340 ASN B C   1 
ATOM   4382 O O   . ASN B 2 340 ? 137.542 152.338 110.610 0.00 19.50  ? 340 ASN B O   1 
ATOM   4383 C CB  . ASN B 2 340 ? 134.963 152.902 111.871 1.00 19.50  ? 340 ASN B CB  1 
ATOM   4384 C CG  . ASN B 2 340 ? 133.677 153.594 111.480 1.00 19.50  ? 340 ASN B CG  1 
ATOM   4385 O OD1 . ASN B 2 340 ? 132.753 153.708 112.281 1.00 19.50  ? 340 ASN B OD1 1 
ATOM   4386 N ND2 . ASN B 2 340 ? 133.615 154.071 110.245 1.00 19.50  ? 340 ASN B ND2 1 
ATOM   4387 N N   . SER C 3 4   ? 114.727 122.444 69.895  1.00 79.07  ? 8   SER G N   1 
ATOM   4388 C CA  . SER C 3 4   ? 116.099 122.853 70.170  1.00 79.07  ? 8   SER G CA  1 
ATOM   4389 C C   . SER C 3 4   ? 116.662 123.685 69.022  1.00 79.07  ? 8   SER G C   1 
ATOM   4390 O O   . SER C 3 4   ? 117.631 124.425 69.197  1.00 79.07  ? 8   SER G O   1 
ATOM   4391 C CB  . SER C 3 4   ? 116.984 121.629 70.412  1.00 79.07  ? 8   SER G CB  1 
ATOM   4392 O OG  . SER C 3 4   ? 117.086 120.839 69.241  1.00 79.07  ? 8   SER G OG  1 
ATOM   4393 N N   . ILE C 3 5   ? 116.050 123.558 67.842  1.00 81.39  ? 9   ILE G N   1 
ATOM   4394 C CA  . ILE C 3 5   ? 116.505 124.327 66.688  1.00 81.39  ? 9   ILE G CA  1 
ATOM   4395 C C   . ILE C 3 5   ? 116.341 125.817 66.947  1.00 81.39  ? 9   ILE G C   1 
ATOM   4396 O O   . ILE C 3 5   ? 117.229 126.619 66.633  1.00 81.39  ? 9   ILE G O   1 
ATOM   4397 C CB  . ILE C 3 5   ? 115.751 123.883 65.421  1.00 81.39  ? 9   ILE G CB  1 
ATOM   4398 C CG1 . ILE C 3 5   ? 116.251 122.513 64.962  1.00 81.39  ? 9   ILE G CG1 1 
ATOM   4399 C CG2 . ILE C 3 5   ? 115.925 124.908 64.309  1.00 81.39  ? 9   ILE G CG2 1 
ATOM   4400 C CD1 . ILE C 3 5   ? 115.280 121.777 64.064  1.00 81.39  ? 9   ILE G CD1 1 
ATOM   4401 N N   . ALA C 3 6   ? 115.203 126.216 67.519  1.00 84.35  ? 10  ALA G N   1 
ATOM   4402 C CA  . ALA C 3 6   ? 114.992 127.625 67.834  1.00 84.35  ? 10  ALA G CA  1 
ATOM   4403 C C   . ALA C 3 6   ? 116.008 128.117 68.857  1.00 84.35  ? 10  ALA G C   1 
ATOM   4404 O O   . ALA C 3 6   ? 116.527 129.233 68.742  1.00 84.35  ? 10  ALA G O   1 
ATOM   4405 C CB  . ALA C 3 6   ? 113.568 127.841 68.345  1.00 84.35  ? 10  ALA G CB  1 
ATOM   4406 N N   . GLN C 3 7   ? 116.298 127.298 69.871  1.00 83.12  ? 11  GLN G N   1 
ATOM   4407 C CA  . GLN C 3 7   ? 117.284 127.689 70.872  1.00 83.12  ? 11  GLN G CA  1 
ATOM   4408 C C   . GLN C 3 7   ? 118.659 127.872 70.244  1.00 83.12  ? 11  GLN G C   1 
ATOM   4409 O O   . GLN C 3 7   ? 119.363 128.845 70.543  1.00 83.12  ? 11  GLN G O   1 
ATOM   4410 C CB  . GLN C 3 7   ? 117.340 126.645 71.987  1.00 83.12  ? 11  GLN G CB  1 
ATOM   4411 C CG  . GLN C 3 7   ? 118.125 127.087 73.211  1.00 83.12  ? 11  GLN G CG  1 
ATOM   4412 C CD  . GLN C 3 7   ? 118.555 125.922 74.081  1.00 83.12  ? 11  GLN G CD  1 
ATOM   4413 O OE1 . GLN C 3 7   ? 118.385 124.760 73.713  1.00 83.12  ? 11  GLN G OE1 1 
ATOM   4414 N NE2 . GLN C 3 7   ? 119.118 126.228 75.244  1.00 83.12  ? 11  GLN G NE2 1 
ATOM   4415 N N   . ALA C 3 8   ? 119.063 126.945 69.374  1.00 82.32  ? 12  ALA G N   1 
ATOM   4416 C CA  . ALA C 3 8   ? 120.354 127.075 68.707  1.00 82.32  ? 12  ALA G CA  1 
ATOM   4417 C C   . ALA C 3 8   ? 120.392 128.314 67.823  1.00 82.32  ? 12  ALA G C   1 
ATOM   4418 O O   . ALA C 3 8   ? 121.405 129.021 67.772  1.00 82.32  ? 12  ALA G O   1 
ATOM   4419 C CB  . ALA C 3 8   ? 120.651 125.820 67.888  1.00 82.32  ? 12  ALA G CB  1 
ATOM   4420 N N   . ARG C 3 9   ? 119.296 128.590 67.114  1.00 84.48  ? 13  ARG G N   1 
ATOM   4421 C CA  . ARG C 3 9   ? 119.235 129.781 66.275  1.00 84.48  ? 13  ARG G CA  1 
ATOM   4422 C C   . ARG C 3 9   ? 119.397 131.042 67.112  1.00 84.48  ? 13  ARG G C   1 
ATOM   4423 O O   . ARG C 3 9   ? 120.154 131.952 66.753  1.00 84.48  ? 13  ARG G O   1 
ATOM   4424 C CB  . ARG C 3 9   ? 117.910 129.809 65.513  1.00 84.48  ? 13  ARG G CB  1 
ATOM   4425 C CG  . ARG C 3 9   ? 117.894 130.744 64.316  1.00 84.48  ? 13  ARG G CG  1 
ATOM   4426 C CD  . ARG C 3 9   ? 118.137 129.987 63.022  1.00 84.48  ? 13  ARG G CD  1 
ATOM   4427 N NE  . ARG C 3 9   ? 117.017 129.115 62.686  1.00 84.48  ? 13  ARG G NE  1 
ATOM   4428 C CZ  . ARG C 3 9   ? 116.859 128.511 61.517  1.00 84.48  ? 13  ARG G CZ  1 
ATOM   4429 N NH1 . ARG C 3 9   ? 117.733 128.663 60.535  1.00 84.48  ? 13  ARG G NH1 1 
ATOM   4430 N NH2 . ARG C 3 9   ? 115.796 127.734 61.326  1.00 84.48  ? 13  ARG G NH2 1 
ATOM   4431 N N   . LYS C 3 10  ? 118.691 131.109 68.243  1.00 82.54  ? 14  LYS G N   1 
ATOM   4432 C CA  . LYS C 3 10  ? 118.796 132.277 69.111  1.00 82.54  ? 14  LYS G CA  1 
ATOM   4433 C C   . LYS C 3 10  ? 120.206 132.424 69.667  1.00 82.54  ? 14  LYS G C   1 
ATOM   4434 O O   . LYS C 3 10  ? 120.742 133.537 69.740  1.00 82.54  ? 14  LYS G O   1 
ATOM   4435 C CB  . LYS C 3 10  ? 117.782 132.175 70.249  1.00 82.54  ? 14  LYS G CB  1 
ATOM   4436 C CG  . LYS C 3 10  ? 117.471 133.500 70.921  1.00 82.54  ? 14  LYS G CG  1 
ATOM   4437 C CD  . LYS C 3 10  ? 116.169 133.437 71.700  1.00 82.54  ? 14  LYS G CD  1 
ATOM   4438 C CE  . LYS C 3 10  ? 114.963 133.585 70.788  1.00 82.54  ? 14  LYS G CE  1 
ATOM   4439 N NZ  . LYS C 3 10  ? 113.700 133.747 71.558  1.00 82.54  ? 14  LYS G NZ  1 
ATOM   4440 N N   . LEU C 3 11  ? 120.822 131.311 70.070  1.00 81.32  ? 15  LEU G N   1 
ATOM   4441 C CA  . LEU C 3 11  ? 122.179 131.373 70.599  1.00 81.32  ? 15  LEU G CA  1 
ATOM   4442 C C   . LEU C 3 11  ? 123.157 131.872 69.545  1.00 81.32  ? 15  LEU G C   1 
ATOM   4443 O O   . LEU C 3 11  ? 124.021 132.711 69.832  1.00 81.32  ? 15  LEU G O   1 
ATOM   4444 C CB  . LEU C 3 11  ? 122.599 129.995 71.110  1.00 81.32  ? 15  LEU G CB  1 
ATOM   4445 C CG  . LEU C 3 11  ? 123.897 129.940 71.918  1.00 81.32  ? 15  LEU G CG  1 
ATOM   4446 C CD1 . LEU C 3 11  ? 123.730 130.650 73.253  1.00 81.32  ? 15  LEU G CD1 1 
ATOM   4447 C CD2 . LEU C 3 11  ? 124.335 128.500 72.125  1.00 81.32  ? 15  LEU G CD2 1 
ATOM   4448 N N   . VAL C 3 12  ? 123.033 131.373 68.313  1.00 78.81  ? 16  VAL G N   1 
ATOM   4449 C CA  . VAL C 3 12  ? 123.922 131.816 67.243  1.00 78.81  ? 16  VAL G CA  1 
ATOM   4450 C C   . VAL C 3 12  ? 123.705 133.296 66.957  1.00 78.81  ? 16  VAL G C   1 
ATOM   4451 O O   . VAL C 3 12  ? 124.664 134.049 66.744  1.00 78.81  ? 16  VAL G O   1 
ATOM   4452 C CB  . VAL C 3 12  ? 123.711 130.959 65.981  1.00 78.81  ? 16  VAL G CB  1 
ATOM   4453 C CG1 . VAL C 3 12  ? 124.263 131.668 64.751  1.00 78.81  ? 16  VAL G CG1 1 
ATOM   4454 C CG2 . VAL C 3 12  ? 124.361 129.594 66.156  1.00 78.81  ? 16  VAL G CG2 1 
ATOM   4455 N N   . GLU C 3 13  ? 122.445 133.737 66.939  1.00 74.92  ? 17  GLU G N   1 
ATOM   4456 C CA  . GLU C 3 13  ? 122.167 135.148 66.690  1.00 74.92  ? 17  GLU G CA  1 
ATOM   4457 C C   . GLU C 3 13  ? 122.782 136.027 67.771  1.00 74.92  ? 17  GLU G C   1 
ATOM   4458 O O   . GLU C 3 13  ? 123.381 137.066 67.470  1.00 74.92  ? 17  GLU G O   1 
ATOM   4459 C CB  . GLU C 3 13  ? 120.658 135.377 66.607  1.00 74.92  ? 17  GLU G CB  1 
ATOM   4460 C CG  . GLU C 3 13  ? 120.273 136.801 66.243  1.00 74.92  ? 17  GLU G CG  1 
ATOM   4461 C CD  . GLU C 3 13  ? 118.774 136.989 66.133  1.00 74.92  ? 17  GLU G CD  1 
ATOM   4462 O OE1 . GLU C 3 13  ? 118.033 136.014 66.376  1.00 74.92  ? 17  GLU G OE1 1 
ATOM   4463 O OE2 . GLU C 3 13  ? 118.337 138.111 65.802  1.00 74.92  ? 17  GLU G OE2 1 
ATOM   4464 N N   . GLN C 3 14  ? 122.640 135.631 69.038  1.00 69.11  ? 18  GLN G N   1 
ATOM   4465 C CA  . GLN C 3 14  ? 123.210 136.425 70.121  1.00 69.11  ? 18  GLN G CA  1 
ATOM   4466 C C   . GLN C 3 14  ? 124.730 136.461 70.037  1.00 69.11  ? 18  GLN G C   1 
ATOM   4467 O O   . GLN C 3 14  ? 125.346 137.513 70.242  1.00 69.11  ? 18  GLN G O   1 
ATOM   4468 C CB  . GLN C 3 14  ? 122.763 135.871 71.473  1.00 69.11  ? 18  GLN G CB  1 
ATOM   4469 C CG  . GLN C 3 14  ? 122.679 136.919 72.572  1.00 69.11  ? 18  GLN G CG  1 
ATOM   4470 C CD  . GLN C 3 14  ? 121.623 137.971 72.297  1.00 69.11  ? 18  GLN G CD  1 
ATOM   4471 O OE1 . GLN C 3 14  ? 120.802 137.822 71.394  1.00 69.11  ? 18  GLN G OE1 1 
ATOM   4472 N NE2 . GLN C 3 14  ? 121.640 139.044 73.078  1.00 69.11  ? 18  GLN G NE2 1 
ATOM   4473 N N   . LEU C 3 15  ? 125.356 135.318 69.746  1.00 71.88  ? 19  LEU G N   1 
ATOM   4474 C CA  . LEU C 3 15  ? 126.809 135.299 69.616  1.00 71.88  ? 19  LEU G CA  1 
ATOM   4475 C C   . LEU C 3 15  ? 127.264 136.203 68.478  1.00 71.88  ? 19  LEU G C   1 
ATOM   4476 O O   . LEU C 3 15  ? 128.242 136.947 68.619  1.00 71.88  ? 19  LEU G O   1 
ATOM   4477 C CB  . LEU C 3 15  ? 127.298 133.870 69.396  1.00 71.88  ? 19  LEU G CB  1 
ATOM   4478 C CG  . LEU C 3 15  ? 127.402 133.023 70.664  1.00 71.88  ? 19  LEU G CG  1 
ATOM   4479 C CD1 . LEU C 3 15  ? 127.259 131.546 70.337  1.00 71.88  ? 19  LEU G CD1 1 
ATOM   4480 C CD2 . LEU C 3 15  ? 128.714 133.292 71.378  1.00 71.88  ? 19  LEU G CD2 1 
ATOM   4481 N N   . LYS C 3 16  ? 126.565 136.159 67.342  1.00 70.42  ? 20  LYS G N   1 
ATOM   4482 C CA  . LYS C 3 16  ? 126.921 137.028 66.226  1.00 70.42  ? 20  LYS G CA  1 
ATOM   4483 C C   . LYS C 3 16  ? 126.766 138.495 66.605  1.00 70.42  ? 20  LYS G C   1 
ATOM   4484 O O   . LYS C 3 16  ? 127.620 139.324 66.272  1.00 70.42  ? 20  LYS G O   1 
ATOM   4485 C CB  . LYS C 3 16  ? 126.059 136.696 65.009  1.00 70.42  ? 20  LYS G CB  1 
ATOM   4486 N N   . MET C 3 17  ? 125.680 138.836 67.303  1.00 64.88  ? 21  MET G N   1 
ATOM   4487 C CA  . MET C 3 17  ? 125.468 140.223 67.700  1.00 64.88  ? 21  MET G CA  1 
ATOM   4488 C C   . MET C 3 17  ? 126.567 140.697 68.644  1.00 64.88  ? 21  MET G C   1 
ATOM   4489 O O   . MET C 3 17  ? 127.047 141.830 68.531  1.00 64.88  ? 21  MET G O   1 
ATOM   4490 C CB  . MET C 3 17  ? 124.097 140.378 68.357  1.00 64.88  ? 21  MET G CB  1 
ATOM   4491 C CG  . MET C 3 17  ? 123.668 141.822 68.558  1.00 64.88  ? 21  MET G CG  1 
ATOM   4492 S SD  . MET C 3 17  ? 122.981 142.131 70.195  1.00 64.88  ? 21  MET G SD  1 
ATOM   4493 C CE  . MET C 3 17  ? 124.478 142.215 71.174  1.00 64.88  ? 21  MET G CE  1 
ATOM   4494 N N   . GLU C 3 18  ? 126.976 139.844 69.582  1.00 62.44  ? 22  GLU G N   1 
ATOM   4495 C CA  . GLU C 3 18  ? 128.024 140.205 70.529  1.00 62.44  ? 22  GLU G CA  1 
ATOM   4496 C C   . GLU C 3 18  ? 129.419 140.147 69.923  1.00 62.44  ? 22  GLU G C   1 
ATOM   4497 O O   . GLU C 3 18  ? 130.360 140.667 70.531  1.00 62.44  ? 22  GLU G O   1 
ATOM   4498 C CB  . GLU C 3 18  ? 127.968 139.286 71.751  1.00 62.44  ? 22  GLU G CB  1 
ATOM   4499 C CG  . GLU C 3 18  ? 126.758 139.508 72.639  1.00 62.44  ? 22  GLU G CG  1 
ATOM   4500 C CD  . GLU C 3 18  ? 126.555 138.385 73.634  1.00 62.44  ? 22  GLU G CD  1 
ATOM   4501 O OE1 . GLU C 3 18  ? 127.533 137.668 73.933  1.00 62.44  ? 22  GLU G OE1 1 
ATOM   4502 O OE2 . GLU C 3 18  ? 125.416 138.219 74.118  1.00 62.44  ? 22  GLU G OE2 1 
ATOM   4503 N N   . ALA C 3 19  ? 129.580 139.527 68.754  1.00 71.40  ? 23  ALA G N   1 
ATOM   4504 C CA  . ALA C 3 19  ? 130.907 139.422 68.155  1.00 71.40  ? 23  ALA G CA  1 
ATOM   4505 C C   . ALA C 3 19  ? 131.460 140.791 67.779  1.00 71.40  ? 23  ALA G C   1 
ATOM   4506 O O   . ALA C 3 19  ? 132.655 141.055 67.957  1.00 71.40  ? 23  ALA G O   1 
ATOM   4507 C CB  . ALA C 3 19  ? 130.854 138.514 66.927  1.00 71.40  ? 23  ALA G CB  1 
ATOM   4508 N N   . ASN C 3 20  ? 130.611 141.677 67.257  1.00 74.06  ? 24  ASN G N   1 
ATOM   4509 C CA  . ASN C 3 20  ? 131.051 142.968 66.724  1.00 74.06  ? 24  ASN G CA  1 
ATOM   4510 C C   . ASN C 3 20  ? 130.769 144.081 67.734  1.00 74.06  ? 24  ASN G C   1 
ATOM   4511 O O   . ASN C 3 20  ? 129.774 144.802 67.660  1.00 74.06  ? 24  ASN G O   1 
ATOM   4512 C CB  . ASN C 3 20  ? 130.395 143.225 65.367  1.00 74.06  ? 24  ASN G CB  1 
ATOM   4513 C CG  . ASN C 3 20  ? 128.879 143.336 65.447  1.00 74.06  ? 24  ASN G CG  1 
ATOM   4514 O OD1 . ASN C 3 20  ? 128.292 143.342 66.528  1.00 74.06  ? 24  ASN G OD1 1 
ATOM   4515 N ND2 . ASN C 3 20  ? 128.238 143.424 64.288  1.00 74.06  ? 24  ASN G ND2 1 
ATOM   4516 N N   . ILE C 3 21  ? 131.692 144.234 68.681  1.00 64.79  ? 25  ILE G N   1 
ATOM   4517 C CA  . ILE C 3 21  ? 131.648 145.312 69.661  1.00 64.79  ? 25  ILE G CA  1 
ATOM   4518 C C   . ILE C 3 21  ? 133.047 145.893 69.803  1.00 64.79  ? 25  ILE G C   1 
ATOM   4519 O O   . ILE C 3 21  ? 134.042 145.160 69.773  1.00 64.79  ? 25  ILE G O   1 
ATOM   4520 C CB  . ILE C 3 21  ? 131.106 144.829 71.024  1.00 64.79  ? 25  ILE G CB  1 
ATOM   4521 C CG1 . ILE C 3 21  ? 132.024 143.770 71.644  1.00 64.79  ? 25  ILE G CG1 1 
ATOM   4522 C CG2 . ILE C 3 21  ? 129.698 144.284 70.869  1.00 64.79  ? 25  ILE G CG2 1 
ATOM   4523 C CD1 . ILE C 3 21  ? 131.731 143.495 73.101  1.00 64.79  ? 25  ILE G CD1 1 
ATOM   4524 N N   . ASP C 3 22  ? 133.122 147.214 69.948  1.00 73.50  ? 26  ASP G N   1 
ATOM   4525 C CA  . ASP C 3 22  ? 134.412 147.875 70.086  1.00 73.50  ? 26  ASP G CA  1 
ATOM   4526 C C   . ASP C 3 22  ? 135.131 147.377 71.332  1.00 73.50  ? 26  ASP G C   1 
ATOM   4527 O O   . ASP C 3 22  ? 134.513 147.124 72.369  1.00 73.50  ? 26  ASP G O   1 
ATOM   4528 C CB  . ASP C 3 22  ? 134.225 149.391 70.159  1.00 73.50  ? 26  ASP G CB  1 
ATOM   4529 C CG  . ASP C 3 22  ? 133.459 149.940 68.973  1.00 73.50  ? 26  ASP G CG  1 
ATOM   4530 O OD1 . ASP C 3 22  ? 133.256 149.189 67.996  1.00 73.50  ? 26  ASP G OD1 1 
ATOM   4531 O OD2 . ASP C 3 22  ? 133.062 151.124 69.016  1.00 73.50  ? 26  ASP G OD2 1 
ATOM   4532 N N   . ARG C 3 23  ? 136.452 147.234 71.224  1.00 59.78  ? 27  ARG G N   1 
ATOM   4533 C CA  . ARG C 3 23  ? 137.275 146.734 72.324  1.00 59.78  ? 27  ARG G CA  1 
ATOM   4534 C C   . ARG C 3 23  ? 138.543 147.579 72.393  1.00 59.78  ? 27  ARG G C   1 
ATOM   4535 O O   . ARG C 3 23  ? 139.489 147.350 71.633  1.00 59.78  ? 27  ARG G O   1 
ATOM   4536 C CB  . ARG C 3 23  ? 137.609 145.260 72.136  1.00 59.78  ? 27  ARG G CB  1 
ATOM   4537 C CG  . ARG C 3 23  ? 136.422 144.325 72.279  1.00 59.78  ? 27  ARG G CG  1 
ATOM   4538 C CD  . ARG C 3 23  ? 136.872 142.872 72.307  1.00 59.78  ? 27  ARG G CD  1 
ATOM   4539 N NE  . ARG C 3 23  ? 135.756 141.956 72.510  1.00 59.78  ? 27  ARG G NE  1 
ATOM   4540 C CZ  . ARG C 3 23  ? 134.932 141.554 71.551  1.00 59.78  ? 27  ARG G CZ  1 
ATOM   4541 N NH1 . ARG C 3 23  ? 135.068 141.968 70.302  1.00 59.78  ? 27  ARG G NH1 1 
ATOM   4542 N NH2 . ARG C 3 23  ? 133.946 140.715 71.855  1.00 59.78  ? 27  ARG G NH2 1 
ATOM   4543 N N   . ILE C 3 24  ? 138.561 148.552 73.305  1.00 51.09  ? 28  ILE G N   1 
ATOM   4544 C CA  . ILE C 3 24  ? 139.784 149.309 73.537  1.00 51.09  ? 28  ILE G CA  1 
ATOM   4545 C C   . ILE C 3 24  ? 140.836 148.399 74.163  1.00 51.09  ? 28  ILE G C   1 
ATOM   4546 O O   . ILE C 3 24  ? 140.542 147.318 74.684  1.00 51.09  ? 28  ILE G O   1 
ATOM   4547 C CB  . ILE C 3 24  ? 139.515 150.539 74.420  1.00 51.09  ? 28  ILE G CB  1 
ATOM   4548 C CG1 . ILE C 3 24  ? 139.164 150.109 75.848  1.00 51.09  ? 28  ILE G CG1 1 
ATOM   4549 C CG2 . ILE C 3 24  ? 138.398 151.381 73.822  1.00 51.09  ? 28  ILE G CG2 1 
ATOM   4550 C CD1 . ILE C 3 24  ? 138.783 151.258 76.756  1.00 51.09  ? 28  ILE G CD1 1 
ATOM   4551 N N   . LYS C 3 25  ? 142.085 148.847 74.107  1.00 54.03  ? 29  LYS G N   1 
ATOM   4552 C CA  . LYS C 3 25  ? 143.172 148.057 74.662  1.00 54.03  ? 29  LYS G CA  1 
ATOM   4553 C C   . LYS C 3 25  ? 143.019 147.930 76.174  1.00 54.03  ? 29  LYS G C   1 
ATOM   4554 O O   . LYS C 3 25  ? 142.553 148.848 76.854  1.00 54.03  ? 29  LYS G O   1 
ATOM   4555 C CB  . LYS C 3 25  ? 144.521 148.687 74.316  1.00 54.03  ? 29  LYS G CB  1 
ATOM   4556 C CG  . LYS C 3 25  ? 145.729 147.834 74.690  1.00 54.03  ? 29  LYS G CG  1 
ATOM   4557 C CD  . LYS C 3 25  ? 145.785 146.529 73.903  1.00 54.03  ? 29  LYS G CD  1 
ATOM   4558 C CE  . LYS C 3 25  ? 146.158 146.756 72.444  1.00 54.03  ? 29  LYS G CE  1 
ATOM   4559 N NZ  . LYS C 3 25  ? 147.558 147.233 72.288  1.00 54.03  ? 29  LYS G NZ  1 
ATOM   4560 N N   . VAL C 3 26  ? 143.417 146.768 76.697  1.00 49.74  ? 30  VAL G N   1 
ATOM   4561 C CA  . VAL C 3 26  ? 143.252 146.495 78.124  1.00 49.74  ? 30  VAL G CA  1 
ATOM   4562 C C   . VAL C 3 26  ? 144.072 147.475 78.955  1.00 49.74  ? 30  VAL G C   1 
ATOM   4563 O O   . VAL C 3 26  ? 143.613 147.965 79.997  1.00 49.74  ? 30  VAL G O   1 
ATOM   4564 C CB  . VAL C 3 26  ? 143.628 145.035 78.431  1.00 49.74  ? 30  VAL G CB  1 
ATOM   4565 C CG1 . VAL C 3 26  ? 145.108 144.794 78.178  1.00 49.74  ? 30  VAL G CG1 1 
ATOM   4566 C CG2 . VAL C 3 26  ? 143.265 144.685 79.864  1.00 49.74  ? 30  VAL G CG2 1 
ATOM   4567 N N   . SER C 3 27  ? 145.299 147.769 78.518  1.00 53.10  ? 31  SER G N   1 
ATOM   4568 C CA  . SER C 3 27  ? 146.138 148.701 79.259  1.00 53.10  ? 31  SER G CA  1 
ATOM   4569 C C   . SER C 3 27  ? 145.435 150.036 79.464  1.00 53.10  ? 31  SER G C   1 
ATOM   4570 O O   . SER C 3 27  ? 145.633 150.686 80.496  1.00 53.10  ? 31  SER G O   1 
ATOM   4571 C CB  . SER C 3 27  ? 147.465 148.910 78.531  1.00 53.10  ? 31  SER G CB  1 
ATOM   4572 O OG  . SER C 3 27  ? 147.318 149.824 77.458  1.00 53.10  ? 31  SER G OG  1 
ATOM   4573 N N   . LYS C 3 28  ? 144.611 150.457 78.504  1.00 50.94  ? 32  LYS G N   1 
ATOM   4574 C CA  . LYS C 3 28  ? 143.853 151.690 78.682  1.00 50.94  ? 32  LYS G CA  1 
ATOM   4575 C C   . LYS C 3 28  ? 142.861 151.563 79.831  1.00 50.94  ? 32  LYS G C   1 
ATOM   4576 O O   . LYS C 3 28  ? 142.691 152.499 80.621  1.00 50.94  ? 32  LYS G O   1 
ATOM   4577 C CB  . LYS C 3 28  ? 143.132 152.053 77.386  1.00 50.94  ? 32  LYS G CB  1 
ATOM   4578 C CG  . LYS C 3 28  ? 142.554 153.456 77.384  1.00 50.94  ? 32  LYS G CG  1 
ATOM   4579 C CD  . LYS C 3 28  ? 142.345 153.970 75.972  1.00 50.94  ? 32  LYS G CD  1 
ATOM   4580 C CE  . LYS C 3 28  ? 141.387 155.149 75.949  1.00 50.94  ? 32  LYS G CE  1 
ATOM   4581 N NZ  . LYS C 3 28  ? 141.862 156.274 76.801  1.00 50.94  ? 32  LYS G NZ  1 
ATOM   4582 N N   . ALA C 3 29  ? 142.191 150.414 79.940  1.00 45.22  ? 33  ALA G N   1 
ATOM   4583 C CA  . ALA C 3 29  ? 141.280 150.200 81.059  1.00 45.22  ? 33  ALA G CA  1 
ATOM   4584 C C   . ALA C 3 29  ? 142.030 150.204 82.384  1.00 45.22  ? 33  ALA G C   1 
ATOM   4585 O O   . ALA C 3 29  ? 141.556 150.772 83.379  1.00 45.22  ? 33  ALA G O   1 
ATOM   4586 C CB  . ALA C 3 29  ? 140.525 148.886 80.875  1.00 45.22  ? 33  ALA G CB  1 
ATOM   4587 N N   . ALA C 3 30  ? 143.204 149.571 82.419  1.00 45.72  ? 34  ALA G N   1 
ATOM   4588 C CA  . ALA C 3 30  ? 144.010 149.586 83.635  1.00 45.72  ? 34  ALA G CA  1 
ATOM   4589 C C   . ALA C 3 30  ? 144.400 151.008 84.014  1.00 45.72  ? 34  ALA G C   1 
ATOM   4590 O O   . ALA C 3 30  ? 144.327 151.391 85.188  1.00 45.72  ? 34  ALA G O   1 
ATOM   4591 C CB  . ALA C 3 30  ? 145.257 148.723 83.445  1.00 45.72  ? 34  ALA G CB  1 
ATOM   4592 N N   . ALA C 3 31  ? 144.821 151.804 83.030  1.00 46.41  ? 35  ALA G N   1 
ATOM   4593 C CA  . ALA C 3 31  ? 145.189 153.188 83.300  1.00 46.41  ? 35  ALA G CA  1 
ATOM   4594 C C   . ALA C 3 31  ? 143.998 153.982 83.812  1.00 46.41  ? 35  ALA G C   1 
ATOM   4595 O O   . ALA C 3 31  ? 144.136 154.800 84.725  1.00 46.41  ? 35  ALA G O   1 
ATOM   4596 C CB  . ALA C 3 31  ? 145.762 153.833 82.041  1.00 46.41  ? 35  ALA G CB  1 
ATOM   4597 N N   . ASP C 3 32  ? 142.817 153.763 83.229  1.00 41.56  ? 36  ASP G N   1 
ATOM   4598 C CA  . ASP C 3 32  ? 141.628 154.472 83.690  1.00 41.56  ? 36  ASP G CA  1 
ATOM   4599 C C   . ASP C 3 32  ? 141.296 154.113 85.134  1.00 41.56  ? 36  ASP G C   1 
ATOM   4600 O O   . ASP C 3 32  ? 140.969 154.993 85.942  1.00 41.56  ? 36  ASP G O   1 
ATOM   4601 C CB  . ASP C 3 32  ? 140.443 154.155 82.782  1.00 41.56  ? 36  ASP G CB  1 
ATOM   4602 C CG  . ASP C 3 32  ? 139.232 155.014 83.084  1.00 41.56  ? 36  ASP G CG  1 
ATOM   4603 O OD1 . ASP C 3 32  ? 139.302 155.836 84.022  1.00 41.56  ? 36  ASP G OD1 1 
ATOM   4604 O OD2 . ASP C 3 32  ? 138.208 154.864 82.385  1.00 41.56  ? 36  ASP G OD2 1 
ATOM   4605 N N   . LEU C 3 33  ? 141.359 152.825 85.475  1.00 34.39  ? 37  LEU G N   1 
ATOM   4606 C CA  . LEU C 3 33  ? 141.079 152.419 86.850  1.00 34.39  ? 37  LEU G CA  1 
ATOM   4607 C C   . LEU C 3 33  ? 142.100 153.009 87.814  1.00 34.39  ? 37  LEU G C   1 
ATOM   4608 O O   . LEU C 3 33  ? 141.739 153.494 88.893  1.00 34.39  ? 37  LEU G O   1 
ATOM   4609 C CB  . LEU C 3 33  ? 141.055 150.897 86.955  1.00 34.39  ? 37  LEU G CB  1 
ATOM   4610 C CG  . LEU C 3 33  ? 139.768 150.234 86.468  1.00 34.39  ? 37  LEU G CG  1 
ATOM   4611 C CD1 . LEU C 3 33  ? 139.938 148.731 86.389  1.00 34.39  ? 37  LEU G CD1 1 
ATOM   4612 C CD2 . LEU C 3 33  ? 138.611 150.585 87.381  1.00 34.39  ? 37  LEU G CD2 1 
ATOM   4613 N N   . MET C 3 34  ? 143.381 152.982 87.442  1.00 43.90  ? 38  MET G N   1 
ATOM   4614 C CA  . MET C 3 34  ? 144.411 153.583 88.282  1.00 43.90  ? 38  MET G CA  1 
ATOM   4615 C C   . MET C 3 34  ? 144.148 155.069 88.486  1.00 43.90  ? 38  MET G C   1 
ATOM   4616 O O   . MET C 3 34  ? 144.255 155.590 89.604  1.00 43.90  ? 38  MET G O   1 
ATOM   4617 C CB  . MET C 3 34  ? 145.783 153.368 87.645  1.00 43.90  ? 38  MET G CB  1 
ATOM   4618 C CG  . MET C 3 34  ? 146.948 153.847 88.487  1.00 43.90  ? 38  MET G CG  1 
ATOM   4619 S SD  . MET C 3 34  ? 148.534 153.559 87.684  1.00 43.90  ? 38  MET G SD  1 
ATOM   4620 C CE  . MET C 3 34  ? 148.671 151.783 87.829  1.00 43.90  ? 38  MET G CE  1 
ATOM   4621 N N   . ALA C 3 35  ? 143.811 155.773 87.404  1.00 38.19  ? 39  ALA G N   1 
ATOM   4622 C CA  . ALA C 3 35  ? 143.565 157.204 87.501  1.00 38.19  ? 39  ALA G CA  1 
ATOM   4623 C C   . ALA C 3 35  ? 142.382 157.495 88.406  1.00 38.19  ? 39  ALA G C   1 
ATOM   4624 O O   . ALA C 3 35  ? 142.434 158.417 89.224  1.00 38.19  ? 39  ALA G O   1 
ATOM   4625 C CB  . ALA C 3 35  ? 143.332 157.789 86.109  1.00 38.19  ? 39  ALA G CB  1 
ATOM   4626 N N   . TYR C 3 36  ? 141.301 156.723 88.277  1.00 30.98  ? 40  TYR G N   1 
ATOM   4627 C CA  . TYR C 3 36  ? 140.154 156.957 89.146  1.00 30.98  ? 40  TYR G CA  1 
ATOM   4628 C C   . TYR C 3 36  ? 140.504 156.676 90.600  1.00 30.98  ? 40  TYR G C   1 
ATOM   4629 O O   . TYR C 3 36  ? 140.096 157.419 91.499  1.00 30.98  ? 40  TYR G O   1 
ATOM   4630 C CB  . TYR C 3 36  ? 138.960 156.108 88.718  1.00 30.98  ? 40  TYR G CB  1 
ATOM   4631 C CG  . TYR C 3 36  ? 137.701 156.492 89.462  1.00 30.98  ? 40  TYR G CG  1 
ATOM   4632 C CD1 . TYR C 3 36  ? 137.386 155.908 90.679  1.00 30.98  ? 40  TYR G CD1 1 
ATOM   4633 C CD2 . TYR C 3 36  ? 136.843 157.458 88.959  1.00 30.98  ? 40  TYR G CD2 1 
ATOM   4634 C CE1 . TYR C 3 36  ? 136.245 156.265 91.368  1.00 30.98  ? 40  TYR G CE1 1 
ATOM   4635 C CE2 . TYR C 3 36  ? 135.698 157.821 89.640  1.00 30.98  ? 40  TYR G CE2 1 
ATOM   4636 C CZ  . TYR C 3 36  ? 135.405 157.222 90.844  1.00 30.98  ? 40  TYR G CZ  1 
ATOM   4637 O OH  . TYR C 3 36  ? 134.267 157.580 91.526  1.00 30.98  ? 40  TYR G OH  1 
ATOM   4638 N N   . CYS C 3 37  ? 141.263 155.607 90.854  1.00 36.11  ? 41  CYS G N   1 
ATOM   4639 C CA  . CYS C 3 37  ? 141.631 155.288 92.228  1.00 36.11  ? 41  CYS G CA  1 
ATOM   4640 C C   . CYS C 3 37  ? 142.475 156.396 92.843  1.00 36.11  ? 41  CYS G C   1 
ATOM   4641 O O   . CYS C 3 37  ? 142.286 156.753 94.011  1.00 36.11  ? 41  CYS G O   1 
ATOM   4642 C CB  . CYS C 3 37  ? 142.380 153.957 92.278  1.00 36.11  ? 41  CYS G CB  1 
ATOM   4643 S SG  . CYS C 3 37  ? 141.308 152.508 92.245  1.00 36.11  ? 41  CYS G SG  1 
ATOM   4644 N N   . GLU C 3 38  ? 143.415 156.951 92.075  1.00 40.35  ? 42  GLU G N   1 
ATOM   4645 C CA  . GLU C 3 38  ? 144.262 158.009 92.617  1.00 40.35  ? 42  GLU G CA  1 
ATOM   4646 C C   . GLU C 3 38  ? 143.492 159.315 92.781  1.00 40.35  ? 42  GLU G C   1 
ATOM   4647 O O   . GLU C 3 38  ? 143.695 160.044 93.757  1.00 40.35  ? 42  GLU G O   1 
ATOM   4648 C CB  . GLU C 3 38  ? 145.482 158.218 91.721  1.00 40.35  ? 42  GLU G CB  1 
ATOM   4649 C CG  . GLU C 3 38  ? 146.543 157.143 91.869  1.00 40.35  ? 42  GLU G CG  1 
ATOM   4650 C CD  . GLU C 3 38  ? 147.820 157.485 91.132  1.00 40.35  ? 42  GLU G CD  1 
ATOM   4651 O OE1 . GLU C 3 38  ? 147.786 158.385 90.268  1.00 40.35  ? 42  GLU G OE1 1 
ATOM   4652 O OE2 . GLU C 3 38  ? 148.860 156.854 91.417  1.00 40.35  ? 42  GLU G OE2 1 
ATOM   4653 N N   . ALA C 3 39  ? 142.605 159.629 91.834  1.00 37.84  ? 43  ALA G N   1 
ATOM   4654 C CA  . ALA C 3 39  ? 141.905 160.909 91.868  1.00 37.84  ? 43  ALA G CA  1 
ATOM   4655 C C   . ALA C 3 39  ? 141.006 161.022 93.090  1.00 37.84  ? 43  ALA G C   1 
ATOM   4656 O O   . ALA C 3 39  ? 140.966 162.071 93.744  1.00 37.84  ? 43  ALA G O   1 
ATOM   4657 C CB  . ALA C 3 39  ? 141.089 161.092 90.589  1.00 37.84  ? 43  ALA G CB  1 
ATOM   4658 N N   . HIS C 3 40  ? 140.271 159.958 93.413  1.00 38.95  ? 44  HIS G N   1 
ATOM   4659 C CA  . HIS C 3 40  ? 139.344 159.954 94.538  1.00 38.95  ? 44  HIS G CA  1 
ATOM   4660 C C   . HIS C 3 40  ? 139.928 159.256 95.761  1.00 38.95  ? 44  HIS G C   1 
ATOM   4661 O O   . HIS C 3 40  ? 139.194 158.622 96.525  1.00 38.95  ? 44  HIS G O   1 
ATOM   4662 C CB  . HIS C 3 40  ? 138.026 159.298 94.129  1.00 38.95  ? 44  HIS G CB  1 
ATOM   4663 C CG  . HIS C 3 40  ? 137.203 160.131 93.197  1.00 38.95  ? 44  HIS G CG  1 
ATOM   4664 N ND1 . HIS C 3 40  ? 136.216 160.986 93.638  1.00 38.95  ? 44  HIS G ND1 1 
ATOM   4665 C CD2 . HIS C 3 40  ? 137.219 160.241 91.848  1.00 38.95  ? 44  HIS G CD2 1 
ATOM   4666 C CE1 . HIS C 3 40  ? 135.660 161.587 92.602  1.00 38.95  ? 44  HIS G CE1 1 
ATOM   4667 N NE2 . HIS C 3 40  ? 136.251 161.152 91.503  1.00 38.95  ? 44  HIS G NE2 1 
ATOM   4668 N N   . ALA C 3 41  ? 141.242 159.362 95.960  1.00 43.63  ? 45  ALA G N   1 
ATOM   4669 C CA  . ALA C 3 41  ? 141.883 158.665 97.071  1.00 43.63  ? 45  ALA G CA  1 
ATOM   4670 C C   . ALA C 3 41  ? 141.571 159.317 98.411  1.00 43.63  ? 45  ALA G C   1 
ATOM   4671 O O   . ALA C 3 41  ? 141.638 158.651 99.449  1.00 43.63  ? 45  ALA G O   1 
ATOM   4672 C CB  . ALA C 3 41  ? 143.394 158.615 96.853  1.00 43.63  ? 45  ALA G CB  1 
ATOM   4673 N N   . LYS C 3 42  ? 141.229 160.603 98.415  1.00 49.23  ? 46  LYS G N   1 
ATOM   4674 C CA  . LYS C 3 42  ? 141.060 161.360 99.648  1.00 49.23  ? 46  LYS G CA  1 
ATOM   4675 C C   . LYS C 3 42  ? 139.624 161.363 100.156 1.00 49.23  ? 46  LYS G C   1 
ATOM   4676 O O   . LYS C 3 42  ? 139.333 162.048 101.141 1.00 49.23  ? 46  LYS G O   1 
ATOM   4677 C CB  . LYS C 3 42  ? 141.532 162.803 99.444  1.00 49.23  ? 46  LYS G CB  1 
ATOM   4678 C CG  . LYS C 3 42  ? 143.034 162.987 99.176  1.00 49.23  ? 46  LYS G CG  1 
ATOM   4679 C CD  . LYS C 3 42  ? 143.917 161.896 99.780  1.00 49.23  ? 46  LYS G CD  1 
ATOM   4680 C CE  . LYS C 3 42  ? 145.358 162.014 99.306  1.00 49.23  ? 46  LYS G CE  1 
ATOM   4681 N NZ  . LYS C 3 42  ? 145.484 161.966 97.822  1.00 49.23  ? 46  LYS G NZ  1 
ATOM   4682 N N   . GLU C 3 43  ? 138.723 160.620 99.516  1.00 50.42  ? 47  GLU G N   1 
ATOM   4683 C CA  . GLU C 3 43  ? 137.337 160.513 99.955  1.00 50.42  ? 47  GLU G CA  1 
ATOM   4684 C C   . GLU C 3 43  ? 137.000 159.095 100.407 1.00 50.42  ? 47  GLU G C   1 
ATOM   4685 O O   . GLU C 3 43  ? 135.871 158.633 100.233 1.00 50.42  ? 47  GLU G O   1 
ATOM   4686 C CB  . GLU C 3 43  ? 136.388 160.957 98.843  1.00 50.42  ? 47  GLU G CB  1 
ATOM   4687 C CG  . GLU C 3 43  ? 136.446 162.444 98.539  1.00 50.42  ? 47  GLU G CG  1 
ATOM   4688 C CD  . GLU C 3 43  ? 136.230 162.748 97.069  1.00 50.42  ? 47  GLU G CD  1 
ATOM   4689 O OE1 . GLU C 3 43  ? 135.370 162.090 96.446  1.00 50.42  ? 47  GLU G OE1 1 
ATOM   4690 O OE2 . GLU C 3 43  ? 136.922 163.640 96.537  1.00 50.42  ? 47  GLU G OE2 1 
ATOM   4691 N N   . ASP C 3 44  ? 137.975 158.394 100.986 1.00 36.35  ? 48  ASP G N   1 
ATOM   4692 C CA  . ASP C 3 44  ? 137.802 157.016 101.441 1.00 36.35  ? 48  ASP G CA  1 
ATOM   4693 C C   . ASP C 3 44  ? 138.272 156.925 102.886 1.00 36.35  ? 48  ASP G C   1 
ATOM   4694 O O   . ASP C 3 44  ? 139.447 156.643 103.153 1.00 36.35  ? 48  ASP G O   1 
ATOM   4695 C CB  . ASP C 3 44  ? 138.567 156.043 100.544 1.00 36.35  ? 48  ASP G CB  1 
ATOM   4696 C CG  . ASP C 3 44  ? 137.927 154.668 100.490 1.00 36.35  ? 48  ASP G CG  1 
ATOM   4697 O OD1 . ASP C 3 44  ? 136.848 154.480 101.090 1.00 36.35  ? 48  ASP G OD1 1 
ATOM   4698 O OD2 . ASP C 3 44  ? 138.505 153.771 99.842  1.00 36.35  ? 48  ASP G OD2 1 
ATOM   4699 N N   . PRO C 3 45  ? 137.382 157.173 103.850 1.00 36.05  ? 49  PRO G N   1 
ATOM   4700 C CA  . PRO C 3 45  ? 137.798 157.067 105.258 1.00 36.05  ? 49  PRO G CA  1 
ATOM   4701 C C   . PRO C 3 45  ? 138.361 155.705 105.621 1.00 36.05  ? 49  PRO G C   1 
ATOM   4702 O O   . PRO C 3 45  ? 139.304 155.626 106.416 1.00 36.05  ? 49  PRO G O   1 
ATOM   4703 C CB  . PRO C 3 45  ? 136.503 157.371 106.022 1.00 36.05  ? 49  PRO G CB  1 
ATOM   4704 C CG  . PRO C 3 45  ? 135.699 158.196 105.088 1.00 36.05  ? 49  PRO G CG  1 
ATOM   4705 C CD  . PRO C 3 45  ? 136.007 157.681 103.718 1.00 36.05  ? 49  PRO G CD  1 
ATOM   4706 N N   . LEU C 3 46  ? 137.809 154.626 105.062 1.00 27.30  ? 50  LEU G N   1 
ATOM   4707 C CA  . LEU C 3 46  ? 138.296 153.293 105.402 1.00 27.30  ? 50  LEU G CA  1 
ATOM   4708 C C   . LEU C 3 46  ? 139.753 153.116 104.992 1.00 27.30  ? 50  LEU G C   1 
ATOM   4709 O O   . LEU C 3 46  ? 140.556 152.560 105.750 1.00 27.30  ? 50  LEU G O   1 
ATOM   4710 C CB  . LEU C 3 46  ? 137.420 152.232 104.739 1.00 27.30  ? 50  LEU G CB  1 
ATOM   4711 C CG  . LEU C 3 46  ? 135.926 152.326 105.053 1.00 27.30  ? 50  LEU G CG  1 
ATOM   4712 C CD1 . LEU C 3 46  ? 135.163 151.201 104.377 1.00 27.30  ? 50  LEU G CD1 1 
ATOM   4713 C CD2 . LEU C 3 46  ? 135.685 152.307 106.553 1.00 27.30  ? 50  LEU G CD2 1 
ATOM   4714 N N   . LEU C 3 47  ? 140.114 153.584 103.797 1.00 32.48  ? 51  LEU G N   1 
ATOM   4715 C CA  . LEU C 3 47  ? 141.496 153.467 103.348 1.00 32.48  ? 51  LEU G CA  1 
ATOM   4716 C C   . LEU C 3 47  ? 142.435 154.255 104.253 1.00 32.48  ? 51  LEU G C   1 
ATOM   4717 O O   . LEU C 3 47  ? 143.517 153.775 104.607 1.00 32.48  ? 51  LEU G O   1 
ATOM   4718 C CB  . LEU C 3 47  ? 141.613 153.946 101.902 1.00 32.48  ? 51  LEU G CB  1 
ATOM   4719 C CG  . LEU C 3 47  ? 143.021 154.072 101.322 1.00 32.48  ? 51  LEU G CG  1 
ATOM   4720 C CD1 . LEU C 3 47  ? 143.825 152.804 101.546 1.00 32.48  ? 51  LEU G CD1 1 
ATOM   4721 C CD2 . LEU C 3 47  ? 142.944 154.402 99.842  1.00 32.48  ? 51  LEU G CD2 1 
ATOM   4722 N N   . THR C 3 48  ? 142.038 155.466 104.636 1.00 42.28  ? 52  THR G N   1 
ATOM   4723 C CA  . THR C 3 48  ? 142.833 156.323 105.513 1.00 42.28  ? 52  THR G CA  1 
ATOM   4724 C C   . THR C 3 48  ? 141.926 156.859 106.614 1.00 42.28  ? 52  THR G C   1 
ATOM   4725 O O   . THR C 3 48  ? 141.175 157.824 106.384 1.00 42.28  ? 52  THR G O   1 
ATOM   4726 C CB  . THR C 3 48  ? 143.472 157.469 104.739 1.00 42.28  ? 52  THR G CB  1 
ATOM   4727 O OG1 . THR C 3 48  ? 142.488 158.096 103.906 1.00 42.28  ? 52  THR G OG1 1 
ATOM   4728 C CG2 . THR C 3 48  ? 144.622 156.959 103.882 1.00 42.28  ? 52  THR G CG2 1 
ATOM   4729 N N   . PRO C 3 49  ? 141.957 156.268 107.819 1.00 52.80  ? 53  PRO G N   1 
ATOM   4730 C CA  . PRO C 3 49  ? 141.038 156.712 108.877 1.00 52.80  ? 53  PRO G CA  1 
ATOM   4731 C C   . PRO C 3 49  ? 141.073 158.213 109.115 1.00 52.80  ? 53  PRO G C   1 
ATOM   4732 O O   . PRO C 3 49  ? 141.973 158.913 108.642 1.00 52.80  ? 53  PRO G O   1 
ATOM   4733 C CB  . PRO C 3 49  ? 141.519 155.949 110.121 1.00 52.80  ? 53  PRO G CB  1 
ATOM   4734 C CG  . PRO C 3 49  ? 142.523 154.948 109.658 1.00 52.80  ? 53  PRO G CG  1 
ATOM   4735 C CD  . PRO C 3 49  ? 142.664 155.028 108.177 1.00 52.80  ? 53  PRO G CD  1 
ATOM   4736 N N   . VAL C 3 50  ? 140.087 158.707 109.851 1.00 57.37  ? 54  VAL G N   1 
ATOM   4737 C CA  . VAL C 3 50  ? 139.953 160.131 110.142 1.00 57.37  ? 54  VAL G CA  1 
ATOM   4738 C C   . VAL C 3 50  ? 139.997 160.298 111.653 1.00 57.37  ? 54  VAL G C   1 
ATOM   4739 O O   . VAL C 3 50  ? 139.777 159.333 112.406 1.00 57.37  ? 54  VAL G O   1 
ATOM   4740 C CB  . VAL C 3 50  ? 138.653 160.718 109.544 1.00 57.37  ? 54  VAL G CB  1 
ATOM   4741 N N   . PRO C 3 51  ? 140.282 161.506 112.138 1.00 65.16  ? 55  PRO G N   1 
ATOM   4742 C CA  . PRO C 3 51  ? 140.302 161.722 113.589 1.00 65.16  ? 55  PRO G CA  1 
ATOM   4743 C C   . PRO C 3 51  ? 138.959 161.380 114.215 1.00 65.16  ? 55  PRO G C   1 
ATOM   4744 O O   . PRO C 3 51  ? 137.903 161.521 113.594 1.00 65.16  ? 55  PRO G O   1 
ATOM   4745 C CB  . PRO C 3 51  ? 140.627 163.215 113.728 1.00 65.16  ? 55  PRO G CB  1 
ATOM   4746 C CG  . PRO C 3 51  ? 140.392 163.806 112.375 1.00 65.16  ? 55  PRO G CG  1 
ATOM   4747 C CD  . PRO C 3 51  ? 140.676 162.717 111.400 1.00 65.16  ? 55  PRO G CD  1 
ATOM   4748 N N   . ALA C 3 52  ? 139.012 160.925 115.468 1.00 59.31  ? 56  ALA G N   1 
ATOM   4749 C CA  . ALA C 3 52  ? 137.817 160.422 116.135 1.00 59.31  ? 56  ALA G CA  1 
ATOM   4750 C C   . ALA C 3 52  ? 136.715 161.467 116.226 1.00 59.31  ? 56  ALA G C   1 
ATOM   4751 O O   . ALA C 3 52  ? 135.546 161.104 116.400 1.00 59.31  ? 56  ALA G O   1 
ATOM   4752 C CB  . ALA C 3 52  ? 138.173 159.923 117.536 1.00 59.31  ? 56  ALA G CB  1 
ATOM   4753 N N   . SER C 3 53  ? 137.052 162.753 116.122 1.00 58.02  ? 57  SER G N   1 
ATOM   4754 C CA  . SER C 3 53  ? 136.026 163.788 116.187 1.00 58.02  ? 57  SER G CA  1 
ATOM   4755 C C   . SER C 3 53  ? 135.042 163.666 115.030 1.00 58.02  ? 57  SER G C   1 
ATOM   4756 O O   . SER C 3 53  ? 133.831 163.835 115.215 1.00 58.02  ? 57  SER G O   1 
ATOM   4757 C CB  . SER C 3 53  ? 136.675 165.170 116.190 1.00 58.02  ? 57  SER G CB  1 
ATOM   4758 N N   . GLU C 3 54  ? 135.542 163.376 113.827 1.00 53.45  ? 58  GLU G N   1 
ATOM   4759 C CA  . GLU C 3 54  ? 134.692 163.344 112.643 1.00 53.45  ? 58  GLU G CA  1 
ATOM   4760 C C   . GLU C 3 54  ? 133.908 162.046 112.501 1.00 53.45  ? 58  GLU G C   1 
ATOM   4761 O O   . GLU C 3 54  ? 132.956 162.000 111.714 1.00 53.45  ? 58  GLU G O   1 
ATOM   4762 C CB  . GLU C 3 54  ? 135.539 163.562 111.387 1.00 53.45  ? 58  GLU G CB  1 
ATOM   4763 N N   . ASN C 3 55  ? 134.278 161.000 113.228 1.00 37.98  ? 59  ASN G N   1 
ATOM   4764 C CA  . ASN C 3 55  ? 133.586 159.721 113.114 1.00 37.98  ? 59  ASN G CA  1 
ATOM   4765 C C   . ASN C 3 55  ? 132.304 159.753 113.938 1.00 37.98  ? 59  ASN G C   1 
ATOM   4766 O O   . ASN C 3 55  ? 132.364 160.013 115.144 1.00 37.98  ? 59  ASN G O   1 
ATOM   4767 C CB  . ASN C 3 55  ? 134.486 158.590 113.590 1.00 37.98  ? 59  ASN G CB  1 
ATOM   4768 C CG  . ASN C 3 55  ? 133.732 157.292 113.792 1.00 37.98  ? 59  ASN G CG  1 
ATOM   4769 O OD1 . ASN C 3 55  ? 133.262 156.998 114.891 1.00 37.98  ? 59  ASN G OD1 1 
ATOM   4770 N ND2 . ASN C 3 55  ? 133.615 156.505 112.729 1.00 37.98  ? 59  ASN G ND2 1 
ATOM   4771 N N   . PRO C 3 56  ? 131.134 159.503 113.341 1.00 29.03  ? 60  PRO G N   1 
ATOM   4772 C CA  . PRO C 3 56  ? 129.891 159.509 114.122 1.00 29.03  ? 60  PRO G CA  1 
ATOM   4773 C C   . PRO C 3 56  ? 129.601 158.205 114.846 1.00 29.03  ? 60  PRO G C   1 
ATOM   4774 O O   . PRO C 3 56  ? 128.622 158.144 115.599 1.00 29.03  ? 60  PRO G O   1 
ATOM   4775 C CB  . PRO C 3 56  ? 128.826 159.790 113.055 1.00 29.03  ? 60  PRO G CB  1 
ATOM   4776 C CG  . PRO C 3 56  ? 129.372 159.187 111.820 1.00 29.03  ? 60  PRO G CG  1 
ATOM   4777 C CD  . PRO C 3 56  ? 130.878 159.263 111.910 1.00 29.03  ? 60  PRO G CD  1 
ATOM   4778 N N   . PHE C 3 57  ? 130.414 157.169 114.649 1.00 24.09  ? 61  PHE G N   1 
ATOM   4779 C CA  . PHE C 3 57  ? 130.213 155.875 115.285 1.00 24.09  ? 61  PHE G CA  1 
ATOM   4780 C C   . PHE C 3 57  ? 131.119 155.667 116.492 1.00 24.09  ? 61  PHE G C   1 
ATOM   4781 O O   . PHE C 3 57  ? 131.219 154.541 116.989 1.00 24.09  ? 61  PHE G O   1 
ATOM   4782 C CB  . PHE C 3 57  ? 130.439 154.751 114.274 1.00 24.09  ? 61  PHE G CB  1 
ATOM   4783 C CG  . PHE C 3 57  ? 129.466 154.763 113.133 1.00 24.09  ? 61  PHE G CG  1 
ATOM   4784 C CD1 . PHE C 3 57  ? 129.709 155.527 112.008 1.00 24.09  ? 61  PHE G CD1 1 
ATOM   4785 C CD2 . PHE C 3 57  ? 128.309 154.010 113.187 1.00 24.09  ? 61  PHE G CD2 1 
ATOM   4786 C CE1 . PHE C 3 57  ? 128.817 155.541 110.961 1.00 24.09  ? 61  PHE G CE1 1 
ATOM   4787 C CE2 . PHE C 3 57  ? 127.414 154.020 112.141 1.00 24.09  ? 61  PHE G CE2 1 
ATOM   4788 C CZ  . PHE C 3 57  ? 127.668 154.787 111.027 1.00 24.09  ? 61  PHE G CZ  1 
ATOM   4789 N N   . ARG C 3 58  ? 131.782 156.716 116.966 1.00 37.79  ? 62  ARG G N   1 
ATOM   4790 C CA  . ARG C 3 58  ? 132.673 156.614 118.118 1.00 37.79  ? 62  ARG G CA  1 
ATOM   4791 C C   . ARG C 3 58  ? 132.002 155.884 119.277 1.00 37.79  ? 62  ARG G C   1 
ATOM   4792 O O   . ARG C 3 58  ? 132.386 156.053 120.434 0.00 37.79  ? 62  ARG G O   1 
ATOM   4793 C CB  . ARG C 3 58  ? 133.115 158.006 118.569 1.00 37.79  ? 62  ARG G CB  1 
ATOM   4794 N N   . GLN D 4 1   ? 135.884 128.972 79.345  1.00 32.60  ? 1   GLN N N   1 
ATOM   4795 C CA  . GLN D 4 1   ? 134.766 128.588 80.251  1.00 32.60  ? 1   GLN N CA  1 
ATOM   4796 C C   . GLN D 4 1   ? 134.691 127.077 80.394  1.00 32.60  ? 1   GLN N C   1 
ATOM   4797 O O   . GLN D 4 1   ? 135.444 126.348 79.750  1.00 32.60  ? 1   GLN N O   1 
ATOM   4798 C CB  . GLN D 4 1   ? 133.438 129.137 79.727  1.00 32.60  ? 1   GLN N CB  1 
ATOM   4799 C CG  . GLN D 4 1   ? 132.972 128.523 78.413  1.00 32.60  ? 1   GLN N CG  1 
ATOM   4800 C CD  . GLN D 4 1   ? 133.736 129.057 77.222  1.00 32.60  ? 1   GLN N CD  1 
ATOM   4801 O OE1 . GLN D 4 1   ? 134.782 129.686 77.373  1.00 32.60  ? 1   GLN N OE1 1 
ATOM   4802 N NE2 . GLN D 4 1   ? 133.218 128.805 76.025  1.00 32.60  ? 1   GLN N NE2 1 
ATOM   4803 N N   . VAL D 4 2   ? 133.776 126.606 81.240  1.00 23.14  ? 2   VAL N N   1 
ATOM   4804 C CA  . VAL D 4 2   ? 133.597 125.170 81.413  1.00 23.14  ? 2   VAL N CA  1 
ATOM   4805 C C   . VAL D 4 2   ? 133.175 124.570 80.081  1.00 23.14  ? 2   VAL N C   1 
ATOM   4806 O O   . VAL D 4 2   ? 132.230 125.046 79.440  1.00 23.14  ? 2   VAL N O   1 
ATOM   4807 C CB  . VAL D 4 2   ? 132.570 124.882 82.509  1.00 23.14  ? 2   VAL N CB  1 
ATOM   4808 C CG1 . VAL D 4 2   ? 132.436 123.382 82.720  1.00 23.14  ? 2   VAL N CG1 1 
ATOM   4809 C CG2 . VAL D 4 2   ? 132.965 125.588 83.797  1.00 23.14  ? 2   VAL N CG2 1 
ATOM   4810 N N   . GLN D 4 3   ? 133.875 123.521 79.656  1.00 26.76  ? 3   GLN N N   1 
ATOM   4811 C CA  . GLN D 4 3   ? 133.606 122.892 78.368  1.00 26.76  ? 3   GLN N CA  1 
ATOM   4812 C C   . GLN D 4 3   ? 134.038 121.437 78.440  1.00 26.76  ? 3   GLN N C   1 
ATOM   4813 O O   . GLN D 4 3   ? 135.207 121.153 78.714  1.00 26.76  ? 3   GLN N O   1 
ATOM   4814 C CB  . GLN D 4 3   ? 134.342 123.618 77.244  1.00 26.76  ? 3   GLN N CB  1 
ATOM   4815 C CG  . GLN D 4 3   ? 133.654 123.530 75.899  1.00 26.76  ? 3   GLN N CG  1 
ATOM   4816 C CD  . GLN D 4 3   ? 134.324 124.394 74.852  1.00 26.76  ? 3   GLN N CD  1 
ATOM   4817 O OE1 . GLN D 4 3   ? 133.910 125.527 74.610  1.00 26.76  ? 3   GLN N OE1 1 
ATOM   4818 N NE2 . GLN D 4 3   ? 135.368 123.863 74.227  1.00 26.76  ? 3   GLN N NE2 1 
ATOM   4819 N N   . LEU D 4 4   ? 133.102 120.527 78.194  1.00 23.25  ? 4   LEU N N   1 
ATOM   4820 C CA  . LEU D 4 4   ? 133.357 119.093 78.229  1.00 23.25  ? 4   LEU N CA  1 
ATOM   4821 C C   . LEU D 4 4   ? 133.082 118.503 76.853  1.00 23.25  ? 4   LEU N C   1 
ATOM   4822 O O   . LEU D 4 4   ? 131.973 118.642 76.325  1.00 23.25  ? 4   LEU N O   1 
ATOM   4823 C CB  . LEU D 4 4   ? 132.480 118.414 79.284  1.00 23.25  ? 4   LEU N CB  1 
ATOM   4824 C CG  . LEU D 4 4   ? 132.628 118.953 80.707  1.00 23.25  ? 4   LEU N CG  1 
ATOM   4825 C CD1 . LEU D 4 4   ? 131.507 118.441 81.590  1.00 23.25  ? 4   LEU N CD1 1 
ATOM   4826 C CD2 . LEU D 4 4   ? 133.978 118.573 81.289  1.00 23.25  ? 4   LEU N CD2 1 
ATOM   4827 N N   . GLN D 4 5   ? 134.084 117.842 76.279  1.00 29.72  ? 5   GLN N N   1 
ATOM   4828 C CA  . GLN D 4 5   ? 133.993 117.272 74.940  1.00 29.72  ? 5   GLN N CA  1 
ATOM   4829 C C   . GLN D 4 5   ? 134.229 115.771 75.012  1.00 29.72  ? 5   GLN N C   1 
ATOM   4830 O O   . GLN D 4 5   ? 135.228 115.324 75.583  1.00 29.72  ? 5   GLN N O   1 
ATOM   4831 C CB  . GLN D 4 5   ? 135.008 117.922 74.000  1.00 29.72  ? 5   GLN N CB  1 
ATOM   4832 C CG  . GLN D 4 5   ? 134.458 119.109 73.231  1.00 29.72  ? 5   GLN N CG  1 
ATOM   4833 C CD  . GLN D 4 5   ? 133.536 118.692 72.104  1.00 29.72  ? 5   GLN N CD  1 
ATOM   4834 O OE1 . GLN D 4 5   ? 133.367 117.503 71.834  1.00 29.72  ? 5   GLN N OE1 1 
ATOM   4835 N NE2 . GLN D 4 5   ? 132.934 119.671 71.439  1.00 29.72  ? 5   GLN N NE2 1 
ATOM   4836 N N   . GLU D 4 6   ? 133.317 115.001 74.424  1.00 28.72  ? 6   GLU N N   1 
ATOM   4837 C CA  . GLU D 4 6   ? 133.367 113.549 74.465  1.00 28.72  ? 6   GLU N CA  1 
ATOM   4838 C C   . GLU D 4 6   ? 133.860 112.999 73.129  1.00 28.72  ? 6   GLU N C   1 
ATOM   4839 O O   . GLU D 4 6   ? 134.164 113.738 72.190  1.00 28.72  ? 6   GLU N O   1 
ATOM   4840 C CB  . GLU D 4 6   ? 131.993 112.969 74.812  1.00 28.72  ? 6   GLU N CB  1 
ATOM   4841 C CG  . GLU D 4 6   ? 131.410 113.454 76.129  1.00 28.72  ? 6   GLU N CG  1 
ATOM   4842 C CD  . GLU D 4 6   ? 131.007 114.911 76.092  1.00 28.72  ? 6   GLU N CD  1 
ATOM   4843 O OE1 . GLU D 4 6   ? 130.800 115.439 74.982  1.00 28.72  ? 6   GLU N OE1 1 
ATOM   4844 O OE2 . GLU D 4 6   ? 130.908 115.529 77.170  1.00 28.72  ? 6   GLU N OE2 1 
ATOM   4845 N N   . SER D 4 7   ? 133.933 111.673 73.047  1.00 28.94  ? 7   SER N N   1 
ATOM   4846 C CA  . SER D 4 7   ? 134.346 110.971 71.839  1.00 28.94  ? 7   SER N CA  1 
ATOM   4847 C C   . SER D 4 7   ? 134.204 109.478 72.105  1.00 28.94  ? 7   SER N C   1 
ATOM   4848 O O   . SER D 4 7   ? 133.892 109.055 73.222  1.00 28.94  ? 7   SER N O   1 
ATOM   4849 C CB  . SER D 4 7   ? 135.780 111.310 71.436  1.00 28.94  ? 7   SER N CB  1 
ATOM   4850 O OG  . SER D 4 7   ? 136.706 110.718 72.331  1.00 28.94  ? 7   SER N OG  1 
ATOM   4851 N N   . GLY D 4 8   ? 134.435 108.684 71.062  1.00 29.51  ? 8   GLY N N   1 
ATOM   4852 C CA  . GLY D 4 8   ? 134.462 107.242 71.176  1.00 29.51  ? 8   GLY N CA  1 
ATOM   4853 C C   . GLY D 4 8   ? 133.152 106.543 70.881  1.00 29.51  ? 8   GLY N C   1 
ATOM   4854 O O   . GLY D 4 8   ? 133.138 105.309 70.798  1.00 29.51  ? 8   GLY N O   1 
ATOM   4855 N N   . GLY D 4 9   ? 132.058 107.281 70.718  1.00 31.39  ? 9   GLY N N   1 
ATOM   4856 C CA  . GLY D 4 9   ? 130.779 106.663 70.428  1.00 31.39  ? 9   GLY N CA  1 
ATOM   4857 C C   . GLY D 4 9   ? 130.795 105.878 69.134  1.00 31.39  ? 9   GLY N C   1 
ATOM   4858 O O   . GLY D 4 9   ? 131.821 105.825 68.450  1.00 31.39  ? 9   GLY N O   1 
ATOM   4859 N N   . GLY D 4 10  ? 129.674 105.259 68.786  1.00 36.36  ? 10  GLY N N   1 
ATOM   4860 C CA  . GLY D 4 10  ? 129.596 104.508 67.548  1.00 36.36  ? 10  GLY N CA  1 
ATOM   4861 C C   . GLY D 4 10  ? 128.520 103.438 67.632  1.00 36.36  ? 10  GLY N C   1 
ATOM   4862 O O   . GLY D 4 10  ? 127.647 103.483 68.497  1.00 36.36  ? 10  GLY N O   1 
ATOM   4863 N N   . LEU D 4 11  ? 128.613 102.483 66.711  1.00 40.39  ? 11  LEU N N   1 
ATOM   4864 C CA  . LEU D 4 11  ? 127.673 101.377 66.609  1.00 40.39  ? 11  LEU N CA  1 
ATOM   4865 C C   . LEU D 4 11  ? 128.412 100.066 66.828  1.00 40.39  ? 11  LEU N C   1 
ATOM   4866 O O   . LEU D 4 11  ? 129.531 99.885  66.338  1.00 40.39  ? 11  LEU N O   1 
ATOM   4867 C CB  . LEU D 4 11  ? 126.981 101.368 65.242  1.00 40.39  ? 11  LEU N CB  1 
ATOM   4868 C CG  . LEU D 4 11  ? 125.916 100.293 65.016  1.00 40.39  ? 11  LEU N CG  1 
ATOM   4869 C CD1 . LEU D 4 11  ? 124.751 100.459 65.978  1.00 40.39  ? 11  LEU N CD1 1 
ATOM   4870 C CD2 . LEU D 4 11  ? 125.429 100.330 63.577  1.00 40.39  ? 11  LEU N CD2 1 
ATOM   4871 N N   . VAL D 4 12  ? 127.786 99.149  67.567  1.00 40.26  ? 12  VAL N N   1 
ATOM   4872 C CA  . VAL D 4 12  ? 128.412 97.879  67.908  1.00 40.26  ? 12  VAL N CA  1 
ATOM   4873 C C   . VAL D 4 12  ? 127.325 96.849  68.177  1.00 40.26  ? 12  VAL N C   1 
ATOM   4874 O O   . VAL D 4 12  ? 126.227 97.179  68.628  1.00 40.26  ? 12  VAL N O   1 
ATOM   4875 C CB  . VAL D 4 12  ? 129.350 98.025  69.127  1.00 40.26  ? 12  VAL N CB  1 
ATOM   4876 C CG1 . VAL D 4 12  ? 128.542 98.127  70.407  1.00 40.26  ? 12  VAL N CG1 1 
ATOM   4877 C CG2 . VAL D 4 12  ? 130.323 96.860  69.191  1.00 40.26  ? 12  VAL N CG2 1 
ATOM   4878 N N   . GLN D 4 13  ? 127.643 95.588  67.894  1.00 47.30  ? 13  GLN N N   1 
ATOM   4879 C CA  . GLN D 4 13  ? 126.707 94.502  68.120  1.00 47.30  ? 13  GLN N CA  1 
ATOM   4880 C C   . GLN D 4 13  ? 126.606 94.191  69.612  1.00 47.30  ? 13  GLN N C   1 
ATOM   4881 O O   . GLN D 4 13  ? 127.450 94.616  70.404  1.00 47.30  ? 13  GLN N O   1 
ATOM   4882 C CB  . GLN D 4 13  ? 127.146 93.259  67.351  1.00 47.30  ? 13  GLN N CB  1 
ATOM   4883 C CG  . GLN D 4 13  ? 127.044 93.399  65.843  1.00 47.30  ? 13  GLN N CG  1 
ATOM   4884 C CD  . GLN D 4 13  ? 125.616 93.591  65.371  1.00 47.30  ? 13  GLN N CD  1 
ATOM   4885 O OE1 . GLN D 4 13  ? 125.235 94.676  64.934  1.00 47.30  ? 13  GLN N OE1 1 
ATOM   4886 N NE2 . GLN D 4 13  ? 124.818 92.534  65.460  1.00 47.30  ? 13  GLN N NE2 1 
ATOM   4887 N N   . PRO D 4 14  ? 125.572 93.454  70.024  1.00 45.93  ? 14  PRO N N   1 
ATOM   4888 C CA  . PRO D 4 14  ? 125.438 93.114  71.444  1.00 45.93  ? 14  PRO N CA  1 
ATOM   4889 C C   . PRO D 4 14  ? 126.670 92.383  71.956  1.00 45.93  ? 14  PRO N C   1 
ATOM   4890 O O   . PRO D 4 14  ? 127.273 91.573  71.251  1.00 45.93  ? 14  PRO N O   1 
ATOM   4891 C CB  . PRO D 4 14  ? 124.193 92.221  71.483  1.00 45.93  ? 14  PRO N CB  1 
ATOM   4892 C CG  . PRO D 4 14  ? 123.425 92.580  70.265  1.00 45.93  ? 14  PRO N CG  1 
ATOM   4893 C CD  . PRO D 4 14  ? 124.436 92.957  69.227  1.00 45.93  ? 14  PRO N CD  1 
ATOM   4894 N N   . GLY D 4 15  ? 127.040 92.683  73.198  1.00 40.41  ? 15  GLY N N   1 
ATOM   4895 C CA  . GLY D 4 15  ? 128.246 92.132  73.778  1.00 40.41  ? 15  GLY N CA  1 
ATOM   4896 C C   . GLY D 4 15  ? 129.526 92.795  73.325  1.00 40.41  ? 15  GLY N C   1 
ATOM   4897 O O   . GLY D 4 15  ? 130.609 92.267  73.603  1.00 40.41  ? 15  GLY N O   1 
ATOM   4898 N N   . GLY D 4 16  ? 129.442 93.931  72.640  1.00 41.30  ? 16  GLY N N   1 
ATOM   4899 C CA  . GLY D 4 16  ? 130.614 94.619  72.146  1.00 41.30  ? 16  GLY N CA  1 
ATOM   4900 C C   . GLY D 4 16  ? 131.280 95.457  73.219  1.00 41.30  ? 16  GLY N C   1 
ATOM   4901 O O   . GLY D 4 16  ? 130.913 95.438  74.395  1.00 41.30  ? 16  GLY N O   1 
ATOM   4902 N N   . SER D 4 17  ? 132.291 96.211  72.790  1.00 38.69  ? 17  SER N N   1 
ATOM   4903 C CA  . SER D 4 17  ? 133.074 97.041  73.692  1.00 38.69  ? 17  SER N CA  1 
ATOM   4904 C C   . SER D 4 17  ? 133.443 98.348  73.006  1.00 38.69  ? 17  SER N C   1 
ATOM   4905 O O   . SER D 4 17  ? 133.767 98.367  71.816  1.00 38.69  ? 17  SER N O   1 
ATOM   4906 C CB  . SER D 4 17  ? 134.344 96.316  74.149  1.00 38.69  ? 17  SER N CB  1 
ATOM   4907 O OG  . SER D 4 17  ? 135.102 95.869  73.039  1.00 38.69  ? 17  SER N OG  1 
ATOM   4908 N N   . LEU D 4 18  ? 133.394 99.435  73.772  1.00 31.82  ? 18  LEU N N   1 
ATOM   4909 C CA  . LEU D 4 18  ? 133.773 100.753 73.287  1.00 31.82  ? 18  LEU N CA  1 
ATOM   4910 C C   . LEU D 4 18  ? 134.344 101.540 74.455  1.00 31.82  ? 18  LEU N C   1 
ATOM   4911 O O   . LEU D 4 18  ? 134.080 101.234 75.620  1.00 31.82  ? 18  LEU N O   1 
ATOM   4912 C CB  . LEU D 4 18  ? 132.581 101.499 72.678  1.00 31.82  ? 18  LEU N CB  1 
ATOM   4913 C CG  . LEU D 4 18  ? 131.941 100.875 71.439  1.00 31.82  ? 18  LEU N CG  1 
ATOM   4914 C CD1 . LEU D 4 18  ? 130.607 101.537 71.146  1.00 31.82  ? 18  LEU N CD1 1 
ATOM   4915 C CD2 . LEU D 4 18  ? 132.871 100.981 70.245  1.00 31.82  ? 18  LEU N CD2 1 
ATOM   4916 N N   . ARG D 4 19  ? 135.132 102.563 74.134  1.00 27.70  ? 19  ARG N N   1 
ATOM   4917 C CA  . ARG D 4 19  ? 135.746 103.426 75.136  1.00 27.70  ? 19  ARG N CA  1 
ATOM   4918 C C   . ARG D 4 19  ? 135.261 104.851 74.920  1.00 27.70  ? 19  ARG N C   1 
ATOM   4919 O O   . ARG D 4 19  ? 135.328 105.369 73.801  1.00 27.70  ? 19  ARG N O   1 
ATOM   4920 C CB  . ARG D 4 19  ? 137.271 103.361 75.066  1.00 27.70  ? 19  ARG N CB  1 
ATOM   4921 C CG  . ARG D 4 19  ? 137.921 103.283 76.432  1.00 27.70  ? 19  ARG N CG  1 
ATOM   4922 C CD  . ARG D 4 19  ? 139.431 103.266 76.347  1.00 27.70  ? 19  ARG N CD  1 
ATOM   4923 N NE  . ARG D 4 19  ? 140.036 103.250 77.673  1.00 27.70  ? 19  ARG N NE  1 
ATOM   4924 C CZ  . ARG D 4 19  ? 141.341 103.250 77.904  1.00 27.70  ? 19  ARG N CZ  1 
ATOM   4925 N NH1 . ARG D 4 19  ? 142.220 103.271 76.915  1.00 27.70  ? 19  ARG N NH1 1 
ATOM   4926 N NH2 . ARG D 4 19  ? 141.778 103.227 79.160  1.00 27.70  ? 19  ARG N NH2 1 
ATOM   4927 N N   . LEU D 4 20  ? 134.779 105.478 75.990  1.00 24.95  ? 20  LEU N N   1 
ATOM   4928 C CA  . LEU D 4 20  ? 134.254 106.840 75.942  1.00 24.95  ? 20  LEU N CA  1 
ATOM   4929 C C   . LEU D 4 20  ? 135.256 107.764 76.626  1.00 24.95  ? 20  LEU N C   1 
ATOM   4930 O O   . LEU D 4 20  ? 135.372 107.769 77.854  1.00 24.95  ? 20  LEU N O   1 
ATOM   4931 C CB  . LEU D 4 20  ? 132.884 106.915 76.603  1.00 24.95  ? 20  LEU N CB  1 
ATOM   4932 C CG  . LEU D 4 20  ? 131.868 105.865 76.157  1.00 24.95  ? 20  LEU N CG  1 
ATOM   4933 C CD1 . LEU D 4 20  ? 130.588 105.988 76.955  1.00 24.95  ? 20  LEU N CD1 1 
ATOM   4934 C CD2 . LEU D 4 20  ? 131.581 105.997 74.676  1.00 24.95  ? 20  LEU N CD2 1 
ATOM   4935 N N   . SER D 4 21  ? 135.976 108.547 75.826  1.00 26.74  ? 21  SER N N   1 
ATOM   4936 C CA  . SER D 4 21  ? 136.930 109.518 76.341  1.00 26.74  ? 21  SER N CA  1 
ATOM   4937 C C   . SER D 4 21  ? 136.262 110.881 76.450  1.00 26.74  ? 21  SER N C   1 
ATOM   4938 O O   . SER D 4 21  ? 135.538 111.300 75.540  1.00 26.74  ? 21  SER N O   1 
ATOM   4939 C CB  . SER D 4 21  ? 138.161 109.603 75.438  1.00 26.74  ? 21  SER N CB  1 
ATOM   4940 O OG  . SER D 4 21  ? 139.020 108.494 75.635  1.00 26.74  ? 21  SER N OG  1 
ATOM   4941 N N   . CYS D 4 22  ? 136.508 111.566 77.561  1.00 25.52  ? 22  CYS N N   1 
ATOM   4942 C CA  . CYS D 4 22  ? 135.892 112.854 77.867  1.00 25.52  ? 22  CYS N CA  1 
ATOM   4943 C C   . CYS D 4 22  ? 137.000 113.896 77.966  1.00 25.52  ? 22  CYS N C   1 
ATOM   4944 O O   . CYS D 4 22  ? 137.699 113.978 78.980  1.00 25.52  ? 22  CYS N O   1 
ATOM   4945 C CB  . CYS D 4 22  ? 135.087 112.760 79.159  1.00 25.52  ? 22  CYS N CB  1 
ATOM   4946 S SG  . CYS D 4 22  ? 134.608 114.332 79.893  1.00 25.52  ? 22  CYS N SG  1 
ATOM   4947 N N   . ALA D 4 23  ? 137.157 114.689 76.910  1.00 27.19  ? 23  ALA N N   1 
ATOM   4948 C CA  . ALA D 4 23  ? 138.167 115.743 76.873  1.00 27.19  ? 23  ALA N CA  1 
ATOM   4949 C C   . ALA D 4 23  ? 137.618 116.971 77.585  1.00 27.19  ? 23  ALA N C   1 
ATOM   4950 O O   . ALA D 4 23  ? 136.668 117.600 77.110  1.00 27.19  ? 23  ALA N O   1 
ATOM   4951 C CB  . ALA D 4 23  ? 138.547 116.065 75.432  1.00 27.19  ? 23  ALA N CB  1 
ATOM   4952 N N   . ALA D 4 24  ? 138.217 117.317 78.721  1.00 24.05  ? 24  ALA N N   1 
ATOM   4953 C CA  . ALA D 4 24  ? 137.743 118.398 79.569  1.00 24.05  ? 24  ALA N CA  1 
ATOM   4954 C C   . ALA D 4 24  ? 138.773 119.518 79.623  1.00 24.05  ? 24  ALA N C   1 
ATOM   4955 O O   . ALA D 4 24  ? 139.981 119.263 79.655  1.00 24.05  ? 24  ALA N O   1 
ATOM   4956 C CB  . ALA D 4 24  ? 137.450 117.896 80.984  1.00 24.05  ? 24  ALA N CB  1 
ATOM   4957 N N   . SER D 4 25  ? 138.285 120.756 79.630  1.00 21.12  ? 25  SER N N   1 
ATOM   4958 C CA  . SER D 4 25  ? 139.143 121.925 79.723  1.00 21.12  ? 25  SER N CA  1 
ATOM   4959 C C   . SER D 4 25  ? 138.354 123.062 80.351  1.00 21.12  ? 25  SER N C   1 
ATOM   4960 O O   . SER D 4 25  ? 137.121 123.042 80.387  1.00 21.12  ? 25  SER N O   1 
ATOM   4961 C CB  . SER D 4 25  ? 139.679 122.341 78.351  1.00 21.12  ? 25  SER N CB  1 
ATOM   4962 O OG  . SER D 4 25  ? 138.634 122.833 77.529  1.00 21.12  ? 25  SER N OG  1 
ATOM   4963 N N   . GLY D 4 26  ? 139.081 124.058 80.849  1.00 18.20  ? 26  GLY N N   1 
ATOM   4964 C CA  . GLY D 4 26  ? 138.464 125.224 81.443  1.00 18.20  ? 26  GLY N CA  1 
ATOM   4965 C C   . GLY D 4 26  ? 138.356 125.215 82.950  1.00 18.20  ? 26  GLY N C   1 
ATOM   4966 O O   . GLY D 4 26  ? 137.637 126.055 83.503  1.00 18.20  ? 26  GLY N O   1 
ATOM   4967 N N   . PHE D 4 27  ? 139.031 124.297 83.636  1.00 16.64  ? 27  PHE N N   1 
ATOM   4968 C CA  . PHE D 4 27  ? 139.043 124.297 85.092  1.00 16.64  ? 27  PHE N CA  1 
ATOM   4969 C C   . PHE D 4 27  ? 140.103 123.317 85.577  1.00 16.64  ? 27  PHE N C   1 
ATOM   4970 O O   . PHE D 4 27  ? 140.718 122.594 84.790  1.00 16.64  ? 27  PHE N O   1 
ATOM   4971 C CB  . PHE D 4 27  ? 137.660 123.958 85.664  1.00 16.64  ? 27  PHE N CB  1 
ATOM   4972 C CG  . PHE D 4 27  ? 137.123 122.625 85.231  1.00 16.64  ? 27  PHE N CG  1 
ATOM   4973 C CD1 . PHE D 4 27  ? 136.547 122.468 83.984  1.00 16.64  ? 27  PHE N CD1 1 
ATOM   4974 C CD2 . PHE D 4 27  ? 137.166 121.538 86.082  1.00 16.64  ? 27  PHE N CD2 1 
ATOM   4975 C CE1 . PHE D 4 27  ? 136.045 121.246 83.588  1.00 16.64  ? 27  PHE N CE1 1 
ATOM   4976 C CE2 . PHE D 4 27  ? 136.663 120.313 85.689  1.00 16.64  ? 27  PHE N CE2 1 
ATOM   4977 C CZ  . PHE D 4 27  ? 136.101 120.169 84.443  1.00 16.64  ? 27  PHE N CZ  1 
ATOM   4978 N N   . THR D 4 28  ? 140.317 123.318 86.890  1.00 17.08  ? 28  THR N N   1 
ATOM   4979 C CA  . THR D 4 28  ? 141.286 122.421 87.514  1.00 17.08  ? 28  THR N CA  1 
ATOM   4980 C C   . THR D 4 28  ? 140.648 121.051 87.703  1.00 17.08  ? 28  THR N C   1 
ATOM   4981 O O   . THR D 4 28  ? 139.745 120.883 88.528  1.00 17.08  ? 28  THR N O   1 
ATOM   4982 C CB  . THR D 4 28  ? 141.756 122.995 88.846  1.00 17.08  ? 28  THR N CB  1 
ATOM   4983 O OG1 . THR D 4 28  ? 142.292 124.307 88.637  1.00 17.08  ? 28  THR N OG1 1 
ATOM   4984 C CG2 . THR D 4 28  ? 142.825 122.113 89.460  1.00 17.08  ? 28  THR N CG2 1 
ATOM   4985 N N   . PHE D 4 29  ? 141.127 120.066 86.942  1.00 20.73  ? 29  PHE N N   1 
ATOM   4986 C CA  . PHE D 4 29  ? 140.438 118.782 86.859  1.00 20.73  ? 29  PHE N CA  1 
ATOM   4987 C C   . PHE D 4 29  ? 140.457 118.040 88.190  1.00 20.73  ? 29  PHE N C   1 
ATOM   4988 O O   . PHE D 4 29  ? 139.477 117.381 88.553  1.00 20.73  ? 29  PHE N O   1 
ATOM   4989 C CB  . PHE D 4 29  ? 141.077 117.933 85.763  1.00 20.73  ? 29  PHE N CB  1 
ATOM   4990 C CG  . PHE D 4 29  ? 140.285 116.716 85.394  1.00 20.73  ? 29  PHE N CG  1 
ATOM   4991 C CD1 . PHE D 4 29  ? 139.024 116.834 84.844  1.00 20.73  ? 29  PHE N CD1 1 
ATOM   4992 C CD2 . PHE D 4 29  ? 140.807 115.451 85.587  1.00 20.73  ? 29  PHE N CD2 1 
ATOM   4993 C CE1 . PHE D 4 29  ? 138.295 115.714 84.502  1.00 20.73  ? 29  PHE N CE1 1 
ATOM   4994 C CE2 . PHE D 4 29  ? 140.083 114.331 85.247  1.00 20.73  ? 29  PHE N CE2 1 
ATOM   4995 C CZ  . PHE D 4 29  ? 138.826 114.463 84.703  1.00 20.73  ? 29  PHE N CZ  1 
ATOM   4996 N N   . SER D 4 30  ? 141.562 118.128 88.930  1.00 17.01  ? 30  SER N N   1 
ATOM   4997 C CA  . SER D 4 30  ? 141.763 117.268 90.090  1.00 17.01  ? 30  SER N CA  1 
ATOM   4998 C C   . SER D 4 30  ? 141.019 117.735 91.335  1.00 17.01  ? 30  SER N C   1 
ATOM   4999 O O   . SER D 4 30  ? 141.030 117.017 92.339  1.00 17.01  ? 30  SER N O   1 
ATOM   5000 C CB  . SER D 4 30  ? 143.254 117.163 90.407  1.00 17.01  ? 30  SER N CB  1 
ATOM   5001 O OG  . SER D 4 30  ? 143.733 118.363 90.982  1.00 17.01  ? 30  SER N OG  1 
ATOM   5002 N N   . ASN D 4 31  ? 140.383 118.904 91.307  1.00 16.49  ? 31  ASN N N   1 
ATOM   5003 C CA  . ASN D 4 31  ? 139.654 119.403 92.466  1.00 16.49  ? 31  ASN N CA  1 
ATOM   5004 C C   . ASN D 4 31  ? 138.191 118.982 92.490  1.00 16.49  ? 31  ASN N C   1 
ATOM   5005 O O   . ASN D 4 31  ? 137.518 119.220 93.497  1.00 16.49  ? 31  ASN N O   1 
ATOM   5006 C CB  . ASN D 4 31  ? 139.719 120.933 92.516  1.00 16.49  ? 31  ASN N CB  1 
ATOM   5007 C CG  . ASN D 4 31  ? 141.108 121.449 92.816  1.00 16.49  ? 31  ASN N CG  1 
ATOM   5008 O OD1 . ASN D 4 31  ? 141.968 120.714 93.297  1.00 16.49  ? 31  ASN N OD1 1 
ATOM   5009 N ND2 . ASN D 4 31  ? 141.336 122.725 92.535  1.00 16.49  ? 31  ASN N ND2 1 
ATOM   5010 N N   . TYR D 4 32  ? 137.683 118.367 91.424  1.00 15.79  ? 32  TYR N N   1 
ATOM   5011 C CA  . TYR D 4 32  ? 136.255 118.138 91.259  1.00 15.79  ? 32  TYR N CA  1 
ATOM   5012 C C   . TYR D 4 32  ? 135.945 116.653 91.163  1.00 15.79  ? 32  TYR N C   1 
ATOM   5013 O O   . TYR D 4 32  ? 136.740 115.870 90.634  1.00 15.79  ? 32  TYR N O   1 
ATOM   5014 C CB  . TYR D 4 32  ? 135.723 118.838 90.006  1.00 15.79  ? 32  TYR N CB  1 
ATOM   5015 C CG  . TYR D 4 32  ? 135.837 120.340 90.041  1.00 15.79  ? 32  TYR N CG  1 
ATOM   5016 C CD1 . TYR D 4 32  ? 136.967 120.979 89.559  1.00 15.79  ? 32  TYR N CD1 1 
ATOM   5017 C CD2 . TYR D 4 32  ? 134.813 121.120 90.553  1.00 15.79  ? 32  TYR N CD2 1 
ATOM   5018 C CE1 . TYR D 4 32  ? 137.075 122.351 89.587  1.00 15.79  ? 32  TYR N CE1 1 
ATOM   5019 C CE2 . TYR D 4 32  ? 134.913 122.493 90.586  1.00 15.79  ? 32  TYR N CE2 1 
ATOM   5020 C CZ  . TYR D 4 32  ? 136.047 123.103 90.102  1.00 15.79  ? 32  TYR N CZ  1 
ATOM   5021 O OH  . TYR D 4 32  ? 136.154 124.471 90.131  1.00 15.79  ? 32  TYR N OH  1 
ATOM   5022 N N   . LYS D 4 33  ? 134.780 116.281 91.681  1.00 18.47  ? 33  LYS N N   1 
ATOM   5023 C CA  . LYS D 4 33  ? 134.218 114.963 91.441  1.00 18.47  ? 33  LYS N CA  1 
ATOM   5024 C C   . LYS D 4 33  ? 133.694 114.888 90.012  1.00 18.47  ? 33  LYS N C   1 
ATOM   5025 O O   . LYS D 4 33  ? 133.525 115.908 89.340  1.00 18.47  ? 33  LYS N O   1 
ATOM   5026 C CB  . LYS D 4 33  ? 133.098 114.696 92.445  1.00 18.47  ? 33  LYS N CB  1 
ATOM   5027 C CG  . LYS D 4 33  ? 132.532 113.295 92.449  1.00 18.47  ? 33  LYS N CG  1 
ATOM   5028 C CD  . LYS D 4 33  ? 131.603 113.123 93.637  1.00 18.47  ? 33  LYS N CD  1 
ATOM   5029 C CE  . LYS D 4 33  ? 130.903 111.785 93.622  1.00 18.47  ? 33  LYS N CE  1 
ATOM   5030 N NZ  . LYS D 4 33  ? 130.120 111.565 94.868  1.00 18.47  ? 33  LYS N NZ  1 
ATOM   5031 N N   . MET D 4 34  ? 133.442 113.670 89.539  1.00 18.94  ? 34  MET N N   1 
ATOM   5032 C CA  . MET D 4 34  ? 132.985 113.456 88.173  1.00 18.94  ? 34  MET N CA  1 
ATOM   5033 C C   . MET D 4 34  ? 131.928 112.362 88.130  1.00 18.94  ? 34  MET N C   1 
ATOM   5034 O O   . MET D 4 34  ? 131.815 111.547 89.048  1.00 18.94  ? 34  MET N O   1 
ATOM   5035 C CB  . MET D 4 34  ? 134.148 113.093 87.251  1.00 18.94  ? 34  MET N CB  1 
ATOM   5036 C CG  . MET D 4 34  ? 135.248 114.140 87.211  1.00 18.94  ? 34  MET N CG  1 
ATOM   5037 S SD  . MET D 4 34  ? 134.675 115.735 86.601  1.00 18.94  ? 34  MET N SD  1 
ATOM   5038 C CE  . MET D 4 34  ? 134.746 115.477 84.834  1.00 18.94  ? 34  MET N CE  1 
ATOM   5039 N N   . ASN D 4 35  ? 131.150 112.361 87.050  1.00 18.80  ? 35  ASN N N   1 
ATOM   5040 C CA  . ASN D 4 35  ? 130.021 111.457 86.900  1.00 18.80  ? 35  ASN N CA  1 
ATOM   5041 C C   . ASN D 4 35  ? 129.834 111.124 85.428  1.00 18.80  ? 35  ASN N C   1 
ATOM   5042 O O   . ASN D 4 35  ? 130.323 111.831 84.545  1.00 18.80  ? 35  ASN N O   1 
ATOM   5043 C CB  . ASN D 4 35  ? 128.721 112.070 87.441  1.00 18.80  ? 35  ASN N CB  1 
ATOM   5044 C CG  . ASN D 4 35  ? 128.831 112.509 88.885  1.00 18.80  ? 35  ASN N CG  1 
ATOM   5045 O OD1 . ASN D 4 35  ? 128.365 111.820 89.790  1.00 18.80  ? 35  ASN N OD1 1 
ATOM   5046 N ND2 . ASN D 4 35  ? 129.426 113.672 89.105  1.00 18.80  ? 35  ASN N ND2 1 
ATOM   5047 N N   . TRP D 4 36  ? 129.120 110.030 85.175  1.00 28.35  ? 36  TRP N N   1 
ATOM   5048 C CA  . TRP D 4 36  ? 128.630 109.684 83.847  1.00 28.35  ? 36  TRP N CA  1 
ATOM   5049 C C   . TRP D 4 36  ? 127.114 109.600 83.907  1.00 28.35  ? 36  TRP N C   1 
ATOM   5050 O O   . TRP D 4 36  ? 126.563 108.891 84.755  1.00 28.35  ? 36  TRP N O   1 
ATOM   5051 C CB  . TRP D 4 36  ? 129.203 108.351 83.359  1.00 28.35  ? 36  TRP N CB  1 
ATOM   5052 C CG  . TRP D 4 36  ? 130.577 108.437 82.775  1.00 28.35  ? 36  TRP N CG  1 
ATOM   5053 C CD1 . TRP D 4 36  ? 131.746 108.124 83.396  1.00 28.35  ? 36  TRP N CD1 1 
ATOM   5054 C CD2 . TRP D 4 36  ? 130.926 108.848 81.448  1.00 28.35  ? 36  TRP N CD2 1 
ATOM   5055 N NE1 . TRP D 4 36  ? 132.803 108.320 82.545  1.00 28.35  ? 36  TRP N NE1 1 
ATOM   5056 C CE2 . TRP D 4 36  ? 132.327 108.766 81.341  1.00 28.35  ? 36  TRP N CE2 1 
ATOM   5057 C CE3 . TRP D 4 36  ? 130.193 109.285 80.343  1.00 28.35  ? 36  TRP N CE3 1 
ATOM   5058 C CZ2 . TRP D 4 36  ? 133.008 109.102 80.175  1.00 28.35  ? 36  TRP N CZ2 1 
ATOM   5059 C CZ3 . TRP D 4 36  ? 130.872 109.618 79.185  1.00 28.35  ? 36  TRP N CZ3 1 
ATOM   5060 C CH2 . TRP D 4 36  ? 132.263 109.525 79.111  1.00 28.35  ? 36  TRP N CH2 1 
ATOM   5061 N N   . VAL D 4 37  ? 126.441 110.321 83.017  1.00 17.00  ? 37  VAL N N   1 
ATOM   5062 C CA  . VAL D 4 37  ? 124.985 110.346 82.969  1.00 17.00  ? 37  VAL N CA  1 
ATOM   5063 C C   . VAL D 4 37  ? 124.548 110.138 81.529  1.00 17.00  ? 37  VAL N C   1 
ATOM   5064 O O   . VAL D 4 37  ? 125.047 110.811 80.621  1.00 17.00  ? 37  VAL N O   1 
ATOM   5065 C CB  . VAL D 4 37  ? 124.413 111.665 83.524  1.00 17.00  ? 37  VAL N CB  1 
ATOM   5066 C CG1 . VAL D 4 37  ? 124.697 111.782 85.012  1.00 17.00  ? 37  VAL N CG1 1 
ATOM   5067 C CG2 . VAL D 4 37  ? 124.981 112.852 82.772  1.00 17.00  ? 37  VAL N CG2 1 
ATOM   5068 N N   . ARG D 4 38  ? 123.610 109.219 81.323  1.00 23.07  ? 38  ARG N N   1 
ATOM   5069 C CA  . ARG D 4 38  ? 123.124 108.865 80.001  1.00 23.07  ? 38  ARG N CA  1 
ATOM   5070 C C   . ARG D 4 38  ? 121.613 109.033 79.939  1.00 23.07  ? 38  ARG N C   1 
ATOM   5071 O O   . ARG D 4 38  ? 120.915 108.884 80.945  1.00 23.07  ? 38  ARG N O   1 
ATOM   5072 C CB  . ARG D 4 38  ? 123.496 107.427 79.648  1.00 23.07  ? 38  ARG N CB  1 
ATOM   5073 C CG  . ARG D 4 38  ? 122.809 106.389 80.514  1.00 23.07  ? 38  ARG N CG  1 
ATOM   5074 C CD  . ARG D 4 38  ? 123.206 104.984 80.116  1.00 23.07  ? 38  ARG N CD  1 
ATOM   5075 N NE  . ARG D 4 38  ? 122.411 103.981 80.814  1.00 23.07  ? 38  ARG N NE  1 
ATOM   5076 C CZ  . ARG D 4 38  ? 122.695 102.686 80.838  1.00 23.07  ? 38  ARG N CZ  1 
ATOM   5077 N NH1 . ARG D 4 38  ? 123.751 102.197 80.209  1.00 23.07  ? 38  ARG N NH1 1 
ATOM   5078 N NH2 . ARG D 4 38  ? 121.899 101.861 81.511  1.00 23.07  ? 38  ARG N NH2 1 
ATOM   5079 N N   . GLN D 4 39  ? 121.114 109.340 78.744  1.00 24.72  ? 39  GLN N N   1 
ATOM   5080 C CA  . GLN D 4 39  ? 119.688 109.559 78.507  1.00 24.72  ? 39  GLN N CA  1 
ATOM   5081 C C   . GLN D 4 39  ? 119.235 108.637 77.381  1.00 24.72  ? 39  GLN N C   1 
ATOM   5082 O O   . GLN D 4 39  ? 119.534 108.884 76.209  1.00 24.72  ? 39  GLN N O   1 
ATOM   5083 C CB  . GLN D 4 39  ? 119.411 111.017 78.162  1.00 24.72  ? 39  GLN N CB  1 
ATOM   5084 C CG  . GLN D 4 39  ? 117.938 111.322 77.973  1.00 24.72  ? 39  GLN N CG  1 
ATOM   5085 C CD  . GLN D 4 39  ? 117.691 112.736 77.500  1.00 24.72  ? 39  GLN N CD  1 
ATOM   5086 O OE1 . GLN D 4 39  ? 118.615 113.438 77.092  1.00 24.72  ? 39  GLN N OE1 1 
ATOM   5087 N NE2 . GLN D 4 39  ? 116.434 113.165 77.555  1.00 24.72  ? 39  GLN N NE2 1 
ATOM   5088 N N   . ALA D 4 40  ? 118.509 107.582 77.734  1.00 27.87  ? 40  ALA N N   1 
ATOM   5089 C CA  . ALA D 4 40  ? 117.993 106.664 76.733  1.00 27.87  ? 40  ALA N CA  1 
ATOM   5090 C C   . ALA D 4 40  ? 116.747 107.246 76.070  1.00 27.87  ? 40  ALA N C   1 
ATOM   5091 O O   . ALA D 4 40  ? 116.096 108.131 76.629  1.00 27.87  ? 40  ALA N O   1 
ATOM   5092 C CB  . ALA D 4 40  ? 117.661 105.319 77.364  1.00 27.87  ? 40  ALA N CB  1 
ATOM   5093 N N   . PRO D 4 41  ? 116.393 106.763 74.879  1.00 30.38  ? 41  PRO N N   1 
ATOM   5094 C CA  . PRO D 4 41  ? 115.244 107.339 74.170  1.00 30.38  ? 41  PRO N CA  1 
ATOM   5095 C C   . PRO D 4 41  ? 113.972 107.257 75.002  1.00 30.38  ? 41  PRO N C   1 
ATOM   5096 O O   . PRO D 4 41  ? 113.707 106.257 75.671  1.00 30.38  ? 41  PRO N O   1 
ATOM   5097 C CB  . PRO D 4 41  ? 115.143 106.483 72.901  1.00 30.38  ? 41  PRO N CB  1 
ATOM   5098 C CG  . PRO D 4 41  ? 116.489 105.876 72.731  1.00 30.38  ? 41  PRO N CG  1 
ATOM   5099 C CD  . PRO D 4 41  ? 117.033 105.684 74.109  1.00 30.38  ? 41  PRO N CD  1 
ATOM   5100 N N   . GLY D 4 42  ? 113.185 108.328 74.951  1.00 33.53  ? 42  GLY N N   1 
ATOM   5101 C CA  . GLY D 4 42  ? 111.916 108.375 75.649  1.00 33.53  ? 42  GLY N CA  1 
ATOM   5102 C C   . GLY D 4 42  ? 112.045 108.133 77.138  1.00 33.53  ? 42  GLY N C   1 
ATOM   5103 O O   . GLY D 4 42  ? 111.242 107.400 77.723  1.00 33.53  ? 42  GLY N O   1 
ATOM   5104 N N   . LYS D 4 43  ? 113.046 108.745 77.766  1.00 34.12  ? 43  LYS N N   1 
ATOM   5105 C CA  . LYS D 4 43  ? 113.303 108.525 79.180  1.00 34.12  ? 43  LYS N CA  1 
ATOM   5106 C C   . LYS D 4 43  ? 113.932 109.773 79.778  1.00 34.12  ? 43  LYS N C   1 
ATOM   5107 O O   . LYS D 4 43  ? 114.425 110.650 79.066  1.00 34.12  ? 43  LYS N O   1 
ATOM   5108 C CB  . LYS D 4 43  ? 114.224 107.317 79.404  1.00 34.12  ? 43  LYS N CB  1 
ATOM   5109 N N   . GLY D 4 44  ? 113.900 109.844 81.107  1.00 27.49  ? 44  GLY N N   1 
ATOM   5110 C CA  . GLY D 4 44  ? 114.575 110.898 81.826  1.00 27.49  ? 44  GLY N CA  1 
ATOM   5111 C C   . GLY D 4 44  ? 116.063 110.634 81.938  1.00 27.49  ? 44  GLY N C   1 
ATOM   5112 O O   . GLY D 4 44  ? 116.585 109.612 81.494  1.00 27.49  ? 44  GLY N O   1 
ATOM   5113 N N   . LEU D 4 45  ? 116.759 111.588 82.546  1.00 20.08  ? 45  LEU N N   1 
ATOM   5114 C CA  . LEU D 4 45  ? 118.200 111.463 82.700  1.00 20.08  ? 45  LEU N CA  1 
ATOM   5115 C C   . LEU D 4 45  ? 118.538 110.411 83.750  1.00 20.08  ? 45  LEU N C   1 
ATOM   5116 O O   . LEU D 4 45  ? 117.780 110.176 84.694  1.00 20.08  ? 45  LEU N O   1 
ATOM   5117 C CB  . LEU D 4 45  ? 118.813 112.807 83.078  1.00 20.08  ? 45  LEU N CB  1 
ATOM   5118 C CG  . LEU D 4 45  ? 119.128 113.699 81.879  1.00 20.08  ? 45  LEU N CG  1 
ATOM   5119 C CD1 . LEU D 4 45  ? 119.037 115.160 82.262  1.00 20.08  ? 45  LEU N CD1 1 
ATOM   5120 C CD2 . LEU D 4 45  ? 120.501 113.371 81.322  1.00 20.08  ? 45  LEU N CD2 1 
ATOM   5121 N N   . GLU D 4 46  ? 119.690 109.775 83.573  1.00 23.44  ? 46  GLU N N   1 
ATOM   5122 C CA  . GLU D 4 46  ? 120.123 108.656 84.394  1.00 23.44  ? 46  GLU N CA  1 
ATOM   5123 C C   . GLU D 4 46  ? 121.517 108.929 84.945  1.00 23.44  ? 46  GLU N C   1 
ATOM   5124 O O   . GLU D 4 46  ? 122.236 109.810 84.472  1.00 23.44  ? 46  GLU N O   1 
ATOM   5125 C CB  . GLU D 4 46  ? 120.097 107.364 83.567  1.00 23.44  ? 46  GLU N CB  1 
ATOM   5126 C CG  . GLU D 4 46  ? 120.448 106.095 84.318  1.00 23.44  ? 46  GLU N CG  1 
ATOM   5127 C CD  . GLU D 4 46  ? 120.345 104.863 83.441  1.00 23.44  ? 46  GLU N CD  1 
ATOM   5128 O OE1 . GLU D 4 46  ? 120.019 105.010 82.243  1.00 23.44  ? 46  GLU N OE1 1 
ATOM   5129 O OE2 . GLU D 4 46  ? 120.587 103.747 83.946  1.00 23.44  ? 46  GLU N OE2 1 
ATOM   5130 N N   . TRP D 4 47  ? 121.892 108.160 85.965  1.00 17.99  ? 47  TRP N N   1 
ATOM   5131 C CA  . TRP D 4 47  ? 123.206 108.257 86.589  1.00 17.99  ? 47  TRP N CA  1 
ATOM   5132 C C   . TRP D 4 47  ? 123.870 106.892 86.524  1.00 17.99  ? 47  TRP N C   1 
ATOM   5133 O O   . TRP D 4 47  ? 123.240 105.882 86.846  1.00 17.99  ? 47  TRP N O   1 
ATOM   5134 C CB  . TRP D 4 47  ? 123.100 108.730 88.044  1.00 17.99  ? 47  TRP N CB  1 
ATOM   5135 C CG  . TRP D 4 47  ? 124.428 108.916 88.712  1.00 17.99  ? 47  TRP N CG  1 
ATOM   5136 C CD1 . TRP D 4 47  ? 125.200 110.041 88.703  1.00 17.99  ? 47  TRP N CD1 1 
ATOM   5137 C CD2 . TRP D 4 47  ? 125.140 107.950 89.492  1.00 17.99  ? 47  TRP N CD2 1 
ATOM   5138 N NE1 . TRP D 4 47  ? 126.347 109.834 89.425  1.00 17.99  ? 47  TRP N NE1 1 
ATOM   5139 C CE2 . TRP D 4 47  ? 126.336 108.557 89.920  1.00 17.99  ? 47  TRP N CE2 1 
ATOM   5140 C CE3 . TRP D 4 47  ? 124.884 106.629 89.869  1.00 17.99  ? 47  TRP N CE3 1 
ATOM   5141 C CZ2 . TRP D 4 47  ? 127.271 107.891 90.704  1.00 17.99  ? 47  TRP N CZ2 1 
ATOM   5142 C CZ3 . TRP D 4 47  ? 125.815 105.969 90.647  1.00 17.99  ? 47  TRP N CZ3 1 
ATOM   5143 C CH2 . TRP D 4 47  ? 126.991 106.601 91.057  1.00 17.99  ? 47  TRP N CH2 1 
ATOM   5144 N N   . VAL D 4 48  ? 125.135 106.860 86.109  1.00 17.48  ? 48  VAL N N   1 
ATOM   5145 C CA  . VAL D 4 48  ? 125.824 105.592 85.901  1.00 17.48  ? 48  VAL N CA  1 
ATOM   5146 C C   . VAL D 4 48  ? 126.931 105.393 86.928  1.00 17.48  ? 48  VAL N C   1 
ATOM   5147 O O   . VAL D 4 48  ? 126.861 104.478 87.753  1.00 17.48  ? 48  VAL N O   1 
ATOM   5148 C CB  . VAL D 4 48  ? 126.388 105.513 84.472  1.00 17.48  ? 48  VAL N CB  1 
ATOM   5149 C CG1 . VAL D 4 48  ? 127.383 104.370 84.350  1.00 17.48  ? 48  VAL N CG1 1 
ATOM   5150 C CG2 . VAL D 4 48  ? 125.259 105.351 83.476  1.00 17.48  ? 48  VAL N CG2 1 
ATOM   5151 N N   . SER D 4 49  ? 127.946 106.255 86.906  1.00 15.51  ? 49  SER N N   1 
ATOM   5152 C CA  . SER D 4 49  ? 129.165 106.026 87.670  1.00 15.51  ? 49  SER N CA  1 
ATOM   5153 C C   . SER D 4 49  ? 129.712 107.356 88.169  1.00 15.51  ? 49  SER N C   1 
ATOM   5154 O O   . SER D 4 49  ? 129.166 108.423 87.879  1.00 15.51  ? 49  SER N O   1 
ATOM   5155 C CB  . SER D 4 49  ? 130.208 105.289 86.824  1.00 15.51  ? 49  SER N CB  1 
ATOM   5156 O OG  . SER D 4 49  ? 131.434 105.165 87.520  1.00 15.51  ? 49  SER N OG  1 
ATOM   5157 N N   . ASP D 4 50  ? 130.801 107.281 88.930  1.00 22.23  ? 50  ASP N N   1 
ATOM   5158 C CA  . ASP D 4 50  ? 131.475 108.465 89.448  1.00 22.23  ? 50  ASP N CA  1 
ATOM   5159 C C   . ASP D 4 50  ? 132.886 108.071 89.865  1.00 22.23  ? 50  ASP N C   1 
ATOM   5160 O O   . ASP D 4 50  ? 133.281 106.908 89.768  1.00 22.23  ? 50  ASP N O   1 
ATOM   5161 C CB  . ASP D 4 50  ? 130.708 109.075 90.621  1.00 22.23  ? 50  ASP N CB  1 
ATOM   5162 C CG  . ASP D 4 50  ? 130.635 108.145 91.808  1.00 22.23  ? 50  ASP N CG  1 
ATOM   5163 O OD1 . ASP D 4 50  ? 131.143 107.012 91.710  1.00 22.23  ? 50  ASP N OD1 1 
ATOM   5164 O OD2 . ASP D 4 50  ? 130.068 108.548 92.843  1.00 22.23  ? 50  ASP N OD2 1 
ATOM   5165 N N   . ILE D 4 51  ? 133.649 109.058 90.325  1.00 18.02  ? 51  ILE N N   1 
ATOM   5166 C CA  . ILE D 4 51  ? 134.999 108.822 90.820  1.00 18.02  ? 51  ILE N CA  1 
ATOM   5167 C C   . ILE D 4 51  ? 135.451 110.083 91.543  1.00 18.02  ? 51  ILE N C   1 
ATOM   5168 O O   . ILE D 4 51  ? 135.137 111.199 91.122  1.00 18.02  ? 51  ILE N O   1 
ATOM   5169 C CB  . ILE D 4 51  ? 135.953 108.427 89.668  1.00 18.02  ? 51  ILE N CB  1 
ATOM   5170 C CG1 . ILE D 4 51  ? 137.390 108.316 90.169  1.00 18.02  ? 51  ILE N CG1 1 
ATOM   5171 C CG2 . ILE D 4 51  ? 135.867 109.432 88.536  1.00 18.02  ? 51  ILE N CG2 1 
ATOM   5172 C CD1 . ILE D 4 51  ? 138.308 107.578 89.222  1.00 18.02  ? 51  ILE N CD1 1 
ATOM   5173 N N   . SER D 4 52  ? 136.200 109.901 92.627  1.00 16.35  ? 52  SER N N   1 
ATOM   5174 C CA  . SER D 4 52  ? 136.524 111.010 93.511  1.00 16.35  ? 52  SER N CA  1 
ATOM   5175 C C   . SER D 4 52  ? 137.635 111.871 92.912  1.00 16.35  ? 52  SER N C   1 
ATOM   5176 O O   . SER D 4 52  ? 138.039 111.708 91.758  1.00 16.35  ? 52  SER N O   1 
ATOM   5177 C CB  . SER D 4 52  ? 136.916 110.481 94.887  1.00 16.35  ? 52  SER N CB  1 
ATOM   5178 O OG  . SER D 4 52  ? 135.796 109.918 95.542  1.00 16.35  ? 52  SER N OG  1 
ATOM   5179 N N   . GLN D 4 53  ? 138.125 112.816 93.718  1.00 18.04  ? 53  GLN N N   1 
ATOM   5180 C CA  . GLN D 4 53  ? 139.130 113.767 93.252  1.00 18.04  ? 53  GLN N CA  1 
ATOM   5181 C C   . GLN D 4 53  ? 140.417 113.056 92.850  1.00 18.04  ? 53  GLN N C   1 
ATOM   5182 O O   . GLN D 4 53  ? 140.822 113.079 91.683  1.00 18.04  ? 53  GLN N O   1 
ATOM   5183 C CB  . GLN D 4 53  ? 139.408 114.801 94.344  1.00 18.04  ? 53  GLN N CB  1 
ATOM   5184 C CG  . GLN D 4 53  ? 138.285 115.798 94.561  1.00 18.04  ? 53  GLN N CG  1 
ATOM   5185 C CD  . GLN D 4 53  ? 137.105 115.196 95.294  1.00 18.04  ? 53  GLN N CD  1 
ATOM   5186 O OE1 . GLN D 4 53  ? 137.112 114.015 95.634  1.00 18.04  ? 53  GLN N OE1 1 
ATOM   5187 N NE2 . GLN D 4 53  ? 136.084 116.006 95.541  1.00 18.04  ? 53  GLN N NE2 1 
ATOM   5188 N N   . SER D 4 54  ? 141.081 112.419 93.815  1.00 17.85  ? 54  SER N N   1 
ATOM   5189 C CA  . SER D 4 54  ? 142.290 111.665 93.502  1.00 17.85  ? 54  SER N CA  1 
ATOM   5190 C C   . SER D 4 54  ? 141.980 110.533 92.534  1.00 17.85  ? 54  SER N C   1 
ATOM   5191 O O   . SER D 4 54  ? 142.727 110.294 91.578  1.00 17.85  ? 54  SER N O   1 
ATOM   5192 C CB  . SER D 4 54  ? 142.911 111.119 94.786  1.00 17.85  ? 54  SER N CB  1 
ATOM   5193 O OG  . SER D 4 54  ? 141.964 110.368 95.525  1.00 17.85  ? 54  SER N OG  1 
ATOM   5194 N N   . GLY D 4 55  ? 140.876 109.827 92.766  1.00 17.14  ? 55  GLY N N   1 
ATOM   5195 C CA  . GLY D 4 55  ? 140.448 108.763 91.883  1.00 17.14  ? 55  GLY N CA  1 
ATOM   5196 C C   . GLY D 4 55  ? 140.384 107.414 92.565  1.00 17.14  ? 55  GLY N C   1 
ATOM   5197 O O   . GLY D 4 55  ? 140.393 106.378 91.896  1.00 17.14  ? 55  GLY N O   1 
ATOM   5198 N N   . ALA D 4 56  ? 140.322 107.411 93.896  1.00 16.58  ? 56  ALA N N   1 
ATOM   5199 C CA  . ALA D 4 56  ? 140.275 106.151 94.638  1.00 16.58  ? 56  ALA N CA  1 
ATOM   5200 C C   . ALA D 4 56  ? 138.851 105.605 94.714  1.00 16.58  ? 56  ALA N C   1 
ATOM   5201 O O   . ALA D 4 56  ? 138.562 104.519 94.206  1.00 16.58  ? 56  ALA N O   1 
ATOM   5202 C CB  . ALA D 4 56  ? 140.855 106.351 96.042  1.00 16.58  ? 56  ALA N CB  1 
ATOM   5203 N N   . SER D 4 57  ? 137.947 106.356 95.340  1.00 15.78  ? 57  SER N N   1 
ATOM   5204 C CA  . SER D 4 57  ? 136.598 105.858 95.569  1.00 15.78  ? 57  SER N CA  1 
ATOM   5205 C C   . SER D 4 57  ? 135.815 105.807 94.265  1.00 15.78  ? 57  SER N C   1 
ATOM   5206 O O   . SER D 4 57  ? 135.856 106.743 93.463  1.00 15.78  ? 57  SER N O   1 
ATOM   5207 C CB  . SER D 4 57  ? 135.878 106.740 96.587  1.00 15.78  ? 57  SER N CB  1 
ATOM   5208 O OG  . SER D 4 57  ? 134.566 106.267 96.830  1.00 15.78  ? 57  SER N OG  1 
ATOM   5209 N N   . ILE D 4 58  ? 135.097 104.705 94.059  1.00 14.91  ? 58  ILE N N   1 
ATOM   5210 C CA  . ILE D 4 58  ? 134.311 104.482 92.855  1.00 14.91  ? 58  ILE N CA  1 
ATOM   5211 C C   . ILE D 4 58  ? 132.931 103.983 93.261  1.00 14.91  ? 58  ILE N C   1 
ATOM   5212 O O   . ILE D 4 58  ? 132.746 103.431 94.348  1.00 14.91  ? 58  ILE N O   1 
ATOM   5213 C CB  . ILE D 4 58  ? 135.000 103.476 91.907  1.00 14.91  ? 58  ILE N CB  1 
ATOM   5214 C CG1 . ILE D 4 58  ? 136.377 103.994 91.481  1.00 14.91  ? 58  ILE N CG1 1 
ATOM   5215 C CG2 . ILE D 4 58  ? 134.140 103.213 90.697  1.00 14.91  ? 58  ILE N CG2 1 
ATOM   5216 C CD1 . ILE D 4 58  ? 137.301 102.915 90.968  1.00 14.91  ? 58  ILE N CD1 1 
ATOM   5217 N N   . SER D 4 59  ? 131.956 104.186 92.378  1.00 20.01  ? 59  SER N N   1 
ATOM   5218 C CA  . SER D 4 59  ? 130.598 103.726 92.620  1.00 20.01  ? 59  SER N CA  1 
ATOM   5219 C C   . SER D 4 59  ? 129.889 103.548 91.286  1.00 20.01  ? 59  SER N C   1 
ATOM   5220 O O   . SER D 4 59  ? 130.088 104.338 90.362  1.00 20.01  ? 59  SER N O   1 
ATOM   5221 C CB  . SER D 4 59  ? 129.824 104.708 93.503  1.00 20.01  ? 59  SER N CB  1 
ATOM   5222 O OG  . SER D 4 59  ? 128.602 104.142 93.943  1.00 20.01  ? 59  SER N OG  1 
ATOM   5223 N N   . TYR D 4 60  ? 129.057 102.510 91.200  1.00 17.16  ? 60  TYR N N   1 
ATOM   5224 C CA  . TYR D 4 60  ? 128.357 102.152 89.976  1.00 17.16  ? 60  TYR N CA  1 
ATOM   5225 C C   . TYR D 4 60  ? 126.862 102.092 90.239  1.00 17.16  ? 60  TYR N C   1 
ATOM   5226 O O   . TYR D 4 60  ? 126.421 101.836 91.363  1.00 17.16  ? 60  TYR N O   1 
ATOM   5227 C CB  . TYR D 4 60  ? 128.818 100.793 89.433  1.00 17.16  ? 60  TYR N CB  1 
ATOM   5228 C CG  . TYR D 4 60  ? 130.264 100.739 89.005  1.00 17.16  ? 60  TYR N CG  1 
ATOM   5229 C CD1 . TYR D 4 60  ? 130.843 101.775 88.299  1.00 17.16  ? 60  TYR N CD1 1 
ATOM   5230 C CD2 . TYR D 4 60  ? 131.053 99.650  89.324  1.00 17.16  ? 60  TYR N CD2 1 
ATOM   5231 C CE1 . TYR D 4 60  ? 132.160 101.723 87.912  1.00 17.16  ? 60  TYR N CE1 1 
ATOM   5232 C CE2 . TYR D 4 60  ? 132.374 99.592  88.944  1.00 17.16  ? 60  TYR N CE2 1 
ATOM   5233 C CZ  . TYR D 4 60  ? 132.923 100.631 88.240  1.00 17.16  ? 60  TYR N CZ  1 
ATOM   5234 O OH  . TYR D 4 60  ? 134.241 100.572 87.859  1.00 17.16  ? 60  TYR N OH  1 
ATOM   5235 N N   . THR D 4 61  ? 126.082 102.325 89.186  1.00 21.10  ? 61  THR N N   1 
ATOM   5236 C CA  . THR D 4 61  ? 124.643 102.188 89.293  1.00 21.10  ? 61  THR N CA  1 
ATOM   5237 C C   . THR D 4 61  ? 124.278 100.720 89.491  1.00 21.10  ? 61  THR N C   1 
ATOM   5238 O O   . THR D 4 61  ? 125.134 99.835  89.534  1.00 21.10  ? 61  THR N O   1 
ATOM   5239 C CB  . THR D 4 61  ? 123.951 102.748 88.051  1.00 21.10  ? 61  THR N CB  1 
ATOM   5240 O OG1 . THR D 4 61  ? 122.563 102.957 88.329  1.00 21.10  ? 61  THR N OG1 1 
ATOM   5241 C CG2 . THR D 4 61  ? 124.081 101.789 86.890  1.00 21.10  ? 61  THR N CG2 1 
ATOM   5242 N N   . GLY D 4 62  ? 122.976 100.466 89.611  1.00 25.73  ? 62  GLY N N   1 
ATOM   5243 C CA  . GLY D 4 62  ? 122.524 99.122  89.937  1.00 25.73  ? 62  GLY N CA  1 
ATOM   5244 C C   . GLY D 4 62  ? 122.909 98.092  88.891  1.00 25.73  ? 62  GLY N C   1 
ATOM   5245 O O   . GLY D 4 62  ? 123.419 97.019  89.220  1.00 25.73  ? 62  GLY N O   1 
ATOM   5246 N N   . SER D 4 63  ? 122.688 98.408  87.614  1.00 25.35  ? 63  SER N N   1 
ATOM   5247 C CA  . SER D 4 63  ? 122.704 97.406  86.555  1.00 25.35  ? 63  SER N CA  1 
ATOM   5248 C C   . SER D 4 63  ? 123.877 97.559  85.589  1.00 25.35  ? 63  SER N C   1 
ATOM   5249 O O   . SER D 4 63  ? 123.734 97.251  84.402  1.00 25.35  ? 63  SER N O   1 
ATOM   5250 C CB  . SER D 4 63  ? 121.386 97.453  85.782  1.00 25.35  ? 63  SER N CB  1 
ATOM   5251 O OG  . SER D 4 63  ? 121.237 98.688  85.107  1.00 25.35  ? 63  SER N OG  1 
ATOM   5252 N N   . VAL D 4 64  ? 125.032 98.029  86.058  1.00 26.22  ? 64  VAL N N   1 
ATOM   5253 C CA  . VAL D 4 64  ? 126.232 98.034  85.225  1.00 26.22  ? 64  VAL N CA  1 
ATOM   5254 C C   . VAL D 4 64  ? 127.411 97.487  86.019  1.00 26.22  ? 64  VAL N C   1 
ATOM   5255 O O   . VAL D 4 64  ? 128.551 97.498  85.541  1.00 26.22  ? 64  VAL N O   1 
ATOM   5256 C CB  . VAL D 4 64  ? 126.550 99.442  84.689  1.00 26.22  ? 64  VAL N CB  1 
ATOM   5257 C CG1 . VAL D 4 64  ? 125.315 100.067 84.057  1.00 26.22  ? 64  VAL N CG1 1 
ATOM   5258 C CG2 . VAL D 4 64  ? 127.122 100.318 85.790  1.00 26.22  ? 64  VAL N CG2 1 
ATOM   5259 N N   . LYS D 4 65  ? 127.151 97.009  87.233  1.00 26.29  ? 65  LYS N N   1 
ATOM   5260 C CA  . LYS D 4 65  ? 128.230 96.562  88.102  1.00 26.29  ? 65  LYS N CA  1 
ATOM   5261 C C   . LYS D 4 65  ? 129.009 95.430  87.448  1.00 26.29  ? 65  LYS N C   1 
ATOM   5262 O O   . LYS D 4 65  ? 128.426 94.491  86.898  1.00 26.29  ? 65  LYS N O   1 
ATOM   5263 C CB  . LYS D 4 65  ? 127.665 96.111  89.447  1.00 26.29  ? 65  LYS N CB  1 
ATOM   5264 C CG  . LYS D 4 65  ? 126.992 97.225  90.228  1.00 26.29  ? 65  LYS N CG  1 
ATOM   5265 C CD  . LYS D 4 65  ? 126.641 96.790  91.638  1.00 26.29  ? 65  LYS N CD  1 
ATOM   5266 C CE  . LYS D 4 65  ? 126.091 97.948  92.450  1.00 26.29  ? 65  LYS N CE  1 
ATOM   5267 N NZ  . LYS D 4 65  ? 125.578 97.508  93.774  1.00 26.29  ? 65  LYS N NZ  1 
ATOM   5268 N N   . GLY D 4 66  ? 130.335 95.527  87.502  1.00 21.89  ? 66  GLY N N   1 
ATOM   5269 C CA  . GLY D 4 66  ? 131.205 94.514  86.947  1.00 21.89  ? 66  GLY N CA  1 
ATOM   5270 C C   . GLY D 4 66  ? 131.442 94.613  85.457  1.00 21.89  ? 66  GLY N C   1 
ATOM   5271 O O   . GLY D 4 66  ? 132.198 93.796  84.916  1.00 21.89  ? 66  GLY N O   1 
ATOM   5272 N N   . ARG D 4 67  ? 130.831 95.582  84.775  1.00 29.31  ? 67  ARG N N   1 
ATOM   5273 C CA  . ARG D 4 67  ? 130.965 95.726  83.332  1.00 29.31  ? 67  ARG N CA  1 
ATOM   5274 C C   . ARG D 4 67  ? 131.825 96.923  82.948  1.00 29.31  ? 67  ARG N C   1 
ATOM   5275 O O   . ARG D 4 67  ? 132.798 96.770  82.204  1.00 29.31  ? 67  ARG N O   1 
ATOM   5276 C CB  . ARG D 4 67  ? 129.575 95.838  82.692  1.00 29.31  ? 67  ARG N CB  1 
ATOM   5277 C CG  . ARG D 4 67  ? 128.752 94.564  82.790  1.00 29.31  ? 67  ARG N CG  1 
ATOM   5278 C CD  . ARG D 4 67  ? 127.595 94.560  81.807  1.00 29.31  ? 67  ARG N CD  1 
ATOM   5279 N NE  . ARG D 4 67  ? 126.473 95.356  82.286  1.00 29.31  ? 67  ARG N NE  1 
ATOM   5280 C CZ  . ARG D 4 67  ? 125.517 95.850  81.510  1.00 29.31  ? 67  ARG N CZ  1 
ATOM   5281 N NH1 . ARG D 4 67  ? 125.506 95.638  80.205  1.00 29.31  ? 67  ARG N NH1 1 
ATOM   5282 N NH2 . ARG D 4 67  ? 124.548 96.577  82.059  1.00 29.31  ? 67  ARG N NH2 1 
ATOM   5283 N N   . PHE D 4 68  ? 131.498 98.115  83.437  1.00 26.53  ? 68  PHE N N   1 
ATOM   5284 C CA  . PHE D 4 68  ? 132.201 99.332  83.063  1.00 26.53  ? 68  PHE N CA  1 
ATOM   5285 C C   . PHE D 4 68  ? 133.139 99.764  84.185  1.00 26.53  ? 68  PHE N C   1 
ATOM   5286 O O   . PHE D 4 68  ? 132.807 99.665  85.368  1.00 26.53  ? 68  PHE N O   1 
ATOM   5287 C CB  . PHE D 4 68  ? 131.212 100.458 82.755  1.00 26.53  ? 68  PHE N CB  1 
ATOM   5288 C CG  . PHE D 4 68  ? 130.193 100.108 81.704  1.00 26.53  ? 68  PHE N CG  1 
ATOM   5289 C CD1 . PHE D 4 68  ? 130.364 99.011  80.877  1.00 26.53  ? 68  PHE N CD1 1 
ATOM   5290 C CD2 . PHE D 4 68  ? 129.053 100.877 81.552  1.00 26.53  ? 68  PHE N CD2 1 
ATOM   5291 C CE1 . PHE D 4 68  ? 129.423 98.699  79.920  1.00 26.53  ? 68  PHE N CE1 1 
ATOM   5292 C CE2 . PHE D 4 68  ? 128.109 100.566 80.597  1.00 26.53  ? 68  PHE N CE2 1 
ATOM   5293 C CZ  . PHE D 4 68  ? 128.294 99.475  79.781  1.00 26.53  ? 68  PHE N CZ  1 
ATOM   5294 N N   . THR D 4 69  ? 134.317 100.253 83.799  1.00 20.99  ? 69  THR N N   1 
ATOM   5295 C CA  . THR D 4 69  ? 135.378 100.620 84.741  1.00 20.99  ? 69  THR N CA  1 
ATOM   5296 C C   . THR D 4 69  ? 135.713 102.099 84.558  1.00 20.99  ? 69  THR N C   1 
ATOM   5297 O O   . THR D 4 69  ? 136.556 102.456 83.731  1.00 20.99  ? 69  THR N O   1 
ATOM   5298 C CB  . THR D 4 69  ? 136.614 99.746  84.542  1.00 20.99  ? 69  THR N CB  1 
ATOM   5299 O OG1 . THR D 4 69  ? 137.297 100.146 83.348  1.00 20.99  ? 69  THR N OG1 1 
ATOM   5300 C CG2 . THR D 4 69  ? 136.225 98.281  84.432  1.00 20.99  ? 69  THR N CG2 1 
ATOM   5301 N N   . ILE D 4 70  ? 135.050 102.955 85.338  1.00 17.79  ? 70  ILE N N   1 
ATOM   5302 C CA  . ILE D 4 70  ? 135.404 104.368 85.363  1.00 17.79  ? 70  ILE N CA  1 
ATOM   5303 C C   . ILE D 4 70  ? 136.880 104.512 85.690  1.00 17.79  ? 70  ILE N C   1 
ATOM   5304 O O   . ILE D 4 70  ? 137.450 103.718 86.444  1.00 17.79  ? 70  ILE N O   1 
ATOM   5305 C CB  . ILE D 4 70  ? 134.534 105.118 86.388  1.00 17.79  ? 70  ILE N CB  1 
ATOM   5306 C CG1 . ILE D 4 70  ? 134.924 106.596 86.464  1.00 17.79  ? 70  ILE N CG1 1 
ATOM   5307 C CG2 . ILE D 4 70  ? 134.679 104.503 87.764  1.00 17.79  ? 70  ILE N CG2 1 
ATOM   5308 C CD1 . ILE D 4 70  ? 134.681 107.355 85.190  1.00 17.79  ? 70  ILE N CD1 1 
ATOM   5309 N N   . SER D 4 71  ? 137.507 105.534 85.116  1.00 20.37  ? 71  SER N N   1 
ATOM   5310 C CA  . SER D 4 71  ? 138.892 105.850 85.429  1.00 20.37  ? 71  SER N CA  1 
ATOM   5311 C C   . SER D 4 71  ? 139.216 107.220 84.859  1.00 20.37  ? 71  SER N C   1 
ATOM   5312 O O   . SER D 4 71  ? 138.815 107.536 83.738  1.00 20.37  ? 71  SER N O   1 
ATOM   5313 C CB  . SER D 4 71  ? 139.846 104.791 84.860  1.00 20.37  ? 71  SER N CB  1 
ATOM   5314 O OG  . SER D 4 71  ? 139.680 104.655 83.461  1.00 20.37  ? 71  SER N OG  1 
ATOM   5315 N N   . ARG D 4 72  ? 139.939 108.025 85.633  1.00 19.59  ? 72  ARG N N   1 
ATOM   5316 C CA  . ARG D 4 72  ? 140.275 109.388 85.251  1.00 19.59  ? 72  ARG N CA  1 
ATOM   5317 C C   . ARG D 4 72  ? 141.786 109.553 85.219  1.00 19.59  ? 72  ARG N C   1 
ATOM   5318 O O   . ARG D 4 72  ? 142.479 109.166 86.164  1.00 19.59  ? 72  ARG N O   1 
ATOM   5319 C CB  . ARG D 4 72  ? 139.652 110.396 86.220  1.00 19.59  ? 72  ARG N CB  1 
ATOM   5320 C CG  . ARG D 4 72  ? 140.392 110.538 87.539  1.00 19.59  ? 72  ARG N CG  1 
ATOM   5321 C CD  . ARG D 4 72  ? 139.492 111.098 88.637  1.00 19.59  ? 72  ARG N CD  1 
ATOM   5322 N NE  . ARG D 4 72  ? 139.517 112.555 88.697  1.00 19.59  ? 72  ARG N NE  1 
ATOM   5323 C CZ  . ARG D 4 72  ? 138.528 113.306 89.162  1.00 19.59  ? 72  ARG N CZ  1 
ATOM   5324 N NH1 . ARG D 4 72  ? 137.405 112.773 89.615  1.00 19.59  ? 72  ARG N NH1 1 
ATOM   5325 N NH2 . ARG D 4 72  ? 138.669 114.628 89.175  1.00 19.59  ? 72  ARG N NH2 1 
ATOM   5326 N N   . ASP D 4 73  ? 142.291 110.126 84.126  1.00 26.30  ? 73  ASP N N   1 
ATOM   5327 C CA  . ASP D 4 73  ? 143.713 110.441 83.993  1.00 26.30  ? 73  ASP N CA  1 
ATOM   5328 C C   . ASP D 4 73  ? 143.903 111.913 84.346  1.00 26.30  ? 73  ASP N C   1 
ATOM   5329 O O   . ASP D 4 73  ? 143.944 112.797 83.487  1.00 26.30  ? 73  ASP N O   1 
ATOM   5330 C CB  . ASP D 4 73  ? 144.208 110.124 82.589  1.00 26.30  ? 73  ASP N CB  1 
ATOM   5331 C CG  . ASP D 4 73  ? 145.720 110.128 82.489  1.00 26.30  ? 73  ASP N CG  1 
ATOM   5332 O OD1 . ASP D 4 73  ? 146.390 110.137 83.543  1.00 26.30  ? 73  ASP N OD1 1 
ATOM   5333 O OD2 . ASP D 4 73  ? 146.241 110.116 81.356  1.00 26.30  ? 73  ASP N OD2 1 
ATOM   5334 N N   . ASN D 4 74  ? 144.021 112.172 85.649  1.00 23.45  ? 74  ASN N N   1 
ATOM   5335 C CA  . ASN D 4 74  ? 144.125 113.545 86.126  1.00 23.45  ? 74  ASN N CA  1 
ATOM   5336 C C   . ASN D 4 74  ? 145.309 114.268 85.503  1.00 23.45  ? 74  ASN N C   1 
ATOM   5337 O O   . ASN D 4 74  ? 145.283 115.495 85.360  1.00 23.45  ? 74  ASN N O   1 
ATOM   5338 C CB  . ASN D 4 74  ? 144.232 113.556 87.651  1.00 23.45  ? 74  ASN N CB  1 
ATOM   5339 C CG  . ASN D 4 74  ? 142.937 113.139 88.330  1.00 23.45  ? 74  ASN N CG  1 
ATOM   5340 O OD1 . ASN D 4 74  ? 141.846 113.375 87.811  1.00 23.45  ? 74  ASN N OD1 1 
ATOM   5341 N ND2 . ASN D 4 74  ? 143.053 112.514 89.493  1.00 23.45  ? 74  ASN N ND2 1 
ATOM   5342 N N   . ALA D 4 75  ? 146.356 113.532 85.128  1.00 28.03  ? 75  ALA N N   1 
ATOM   5343 C CA  . ALA D 4 75  ? 147.505 114.162 84.487  1.00 28.03  ? 75  ALA N CA  1 
ATOM   5344 C C   . ALA D 4 75  ? 147.137 114.730 83.122  1.00 28.03  ? 75  ALA N C   1 
ATOM   5345 O O   . ALA D 4 75  ? 147.552 115.843 82.775  1.00 28.03  ? 75  ALA N O   1 
ATOM   5346 C CB  . ALA D 4 75  ? 148.648 113.157 84.358  1.00 28.03  ? 75  ALA N CB  1 
ATOM   5347 N N   . LYS D 4 76  ? 146.368 113.984 82.331  1.00 29.66  ? 76  LYS N N   1 
ATOM   5348 C CA  . LYS D 4 76  ? 145.977 114.407 80.993  1.00 29.66  ? 76  LYS N CA  1 
ATOM   5349 C C   . LYS D 4 76  ? 144.580 115.007 80.943  1.00 29.66  ? 76  LYS N C   1 
ATOM   5350 O O   . LYS D 4 76  ? 144.109 115.352 79.855  1.00 29.66  ? 76  LYS N O   1 
ATOM   5351 C CB  . LYS D 4 76  ? 146.060 113.224 80.022  1.00 29.66  ? 76  LYS N CB  1 
ATOM   5352 N N   . ASN D 4 77  ? 143.906 115.140 82.084  1.00 27.88  ? 77  ASN N N   1 
ATOM   5353 C CA  . ASN D 4 77  ? 142.616 115.820 82.162  1.00 27.88  ? 77  ASN N CA  1 
ATOM   5354 C C   . ASN D 4 77  ? 141.585 115.146 81.255  1.00 27.88  ? 77  ASN N C   1 
ATOM   5355 O O   . ASN D 4 77  ? 141.083 115.734 80.296  1.00 27.88  ? 77  ASN N O   1 
ATOM   5356 C CB  . ASN D 4 77  ? 142.771 117.301 81.799  1.00 27.88  ? 77  ASN N CB  1 
ATOM   5357 C CG  . ASN D 4 77  ? 143.536 118.083 82.844  1.00 27.88  ? 77  ASN N CG  1 
ATOM   5358 O OD1 . ASN D 4 77  ? 143.340 117.901 84.044  1.00 27.88  ? 77  ASN N OD1 1 
ATOM   5359 N ND2 . ASN D 4 77  ? 144.416 118.970 82.392  1.00 27.88  ? 77  ASN N ND2 1 
ATOM   5360 N N   . THR D 4 78  ? 141.277 113.888 81.569  1.00 27.16  ? 78  THR N N   1 
ATOM   5361 C CA  . THR D 4 78  ? 140.321 113.127 80.775  1.00 27.16  ? 78  THR N CA  1 
ATOM   5362 C C   . THR D 4 78  ? 139.688 112.034 81.625  1.00 27.16  ? 78  THR N C   1 
ATOM   5363 O O   . THR D 4 78  ? 140.333 111.473 82.513  1.00 27.16  ? 78  THR N O   1 
ATOM   5364 C CB  . THR D 4 78  ? 140.988 112.511 79.537  1.00 27.16  ? 78  THR N CB  1 
ATOM   5365 O OG1 . THR D 4 78  ? 140.002 111.840 78.744  1.00 27.16  ? 78  THR N OG1 1 
ATOM   5366 C CG2 . THR D 4 78  ? 142.076 111.528 79.936  1.00 27.16  ? 78  THR N CG2 1 
ATOM   5367 N N   . LEU D 4 79  ? 138.424 111.740 81.338  1.00 19.96  ? 79  LEU N N   1 
ATOM   5368 C CA  . LEU D 4 79  ? 137.654 110.727 82.041  1.00 19.96  ? 79  LEU N CA  1 
ATOM   5369 C C   . LEU D 4 79  ? 137.322 109.597 81.076  1.00 19.96  ? 79  LEU N C   1 
ATOM   5370 O O   . LEU D 4 79  ? 137.022 109.843 79.905  1.00 19.96  ? 79  LEU N O   1 
ATOM   5371 C CB  . LEU D 4 79  ? 136.370 111.332 82.615  1.00 19.96  ? 79  LEU N CB  1 
ATOM   5372 C CG  . LEU D 4 79  ? 135.569 110.519 83.633  1.00 19.96  ? 79  LEU N CG  1 
ATOM   5373 C CD1 . LEU D 4 79  ? 136.151 110.680 85.025  1.00 19.96  ? 79  LEU N CD1 1 
ATOM   5374 C CD2 . LEU D 4 79  ? 134.113 110.943 83.618  1.00 19.96  ? 79  LEU N CD2 1 
ATOM   5375 N N   . TYR D 4 80  ? 137.380 108.362 81.564  1.00 22.85  ? 80  TYR N N   1 
ATOM   5376 C CA  . TYR D 4 80  ? 137.198 107.178 80.736  1.00 22.85  ? 80  TYR N CA  1 
ATOM   5377 C C   . TYR D 4 80  ? 135.948 106.410 81.140  1.00 22.85  ? 80  TYR N C   1 
ATOM   5378 O O   . TYR D 4 80  ? 135.374 106.619 82.211  1.00 22.85  ? 80  TYR N O   1 
ATOM   5379 C CB  . TYR D 4 80  ? 138.405 106.241 80.840  1.00 22.85  ? 80  TYR N CB  1 
ATOM   5380 C CG  . TYR D 4 80  ? 139.665 106.757 80.193  1.00 22.85  ? 80  TYR N CG  1 
ATOM   5381 C CD1 . TYR D 4 80  ? 139.791 106.798 78.815  1.00 22.85  ? 80  TYR N CD1 1 
ATOM   5382 C CD2 . TYR D 4 80  ? 140.735 107.185 80.961  1.00 22.85  ? 80  TYR N CD2 1 
ATOM   5383 C CE1 . TYR D 4 80  ? 140.943 107.261 78.219  1.00 22.85  ? 80  TYR N CE1 1 
ATOM   5384 C CE2 . TYR D 4 80  ? 141.891 107.649 80.375  1.00 22.85  ? 80  TYR N CE2 1 
ATOM   5385 C CZ  . TYR D 4 80  ? 141.990 107.685 79.004  1.00 22.85  ? 80  TYR N CZ  1 
ATOM   5386 O OH  . TYR D 4 80  ? 143.142 108.148 78.416  1.00 22.85  ? 80  TYR N OH  1 
ATOM   5387 N N   . LEU D 4 81  ? 135.530 105.511 80.248  1.00 23.39  ? 81  LEU N N   1 
ATOM   5388 C CA  . LEU D 4 81  ? 134.526 104.499 80.572  1.00 23.39  ? 81  LEU N CA  1 
ATOM   5389 C C   . LEU D 4 81  ? 134.740 103.339 79.603  1.00 23.39  ? 81  LEU N C   1 
ATOM   5390 O O   . LEU D 4 81  ? 134.328 103.415 78.443  1.00 23.39  ? 81  LEU N O   1 
ATOM   5391 C CB  . LEU D 4 81  ? 133.111 105.052 80.475  1.00 23.39  ? 81  LEU N CB  1 
ATOM   5392 C CG  . LEU D 4 81  ? 132.022 104.125 81.016  1.00 23.39  ? 81  LEU N CG  1 
ATOM   5393 C CD1 . LEU D 4 81  ? 132.092 104.040 82.527  1.00 23.39  ? 81  LEU N CD1 1 
ATOM   5394 C CD2 . LEU D 4 81  ? 130.645 104.576 80.570  1.00 23.39  ? 81  LEU N CD2 1 
ATOM   5395 N N   . GLN D 4 82  ? 135.379 102.278 80.085  1.00 27.37  ? 82  GLN N N   1 
ATOM   5396 C CA  . GLN D 4 82  ? 135.666 101.110 79.260  1.00 27.37  ? 82  GLN N CA  1 
ATOM   5397 C C   . GLN D 4 82  ? 134.425 100.224 79.219  1.00 27.37  ? 82  GLN N C   1 
ATOM   5398 O O   . GLN D 4 82  ? 134.140 99.496  80.176  1.00 27.37  ? 82  GLN N O   1 
ATOM   5399 C CB  . GLN D 4 82  ? 136.874 100.363 79.819  1.00 27.37  ? 82  GLN N CB  1 
ATOM   5400 C CG  . GLN D 4 82  ? 137.058 98.955  79.286  1.00 27.37  ? 82  GLN N CG  1 
ATOM   5401 C CD  . GLN D 4 82  ? 136.995 98.887  77.777  1.00 27.37  ? 82  GLN N CD  1 
ATOM   5402 O OE1 . GLN D 4 82  ? 135.921 98.968  77.185  1.00 27.37  ? 82  GLN N OE1 1 
ATOM   5403 N NE2 . GLN D 4 82  ? 138.152 98.743  77.145  1.00 27.37  ? 82  GLN N NE2 1 
ATOM   5404 N N   . MET D 4 83  ? 133.687 100.280 78.114  1.00 31.77  ? 83  MET N N   1 
ATOM   5405 C CA  . MET D 4 83  ? 132.441 99.540  77.977  1.00 31.77  ? 83  MET N CA  1 
ATOM   5406 C C   . MET D 4 83  ? 132.724 98.102  77.563  1.00 31.77  ? 83  MET N C   1 
ATOM   5407 O O   . MET D 4 83  ? 133.583 97.851  76.712  1.00 31.77  ? 83  MET N O   1 
ATOM   5408 C CB  . MET D 4 83  ? 131.527 100.211 76.952  1.00 31.77  ? 83  MET N CB  1 
ATOM   5409 C CG  . MET D 4 83  ? 131.405 101.713 77.117  1.00 31.77  ? 83  MET N CG  1 
ATOM   5410 S SD  . MET D 4 83  ? 129.948 102.388 76.298  1.00 31.77  ? 83  MET N SD  1 
ATOM   5411 C CE  . MET D 4 83  ? 128.771 102.398 77.644  1.00 31.77  ? 83  MET N CE  1 
ATOM   5412 N N   . ASN D 4 84  ? 132.000 97.162  78.169  1.00 35.66  ? 84  ASN N N   1 
ATOM   5413 C CA  . ASN D 4 84  ? 132.126 95.749  77.840  1.00 35.66  ? 84  ASN N CA  1 
ATOM   5414 C C   . ASN D 4 84  ? 130.784 95.067  78.050  1.00 35.66  ? 84  ASN N C   1 
ATOM   5415 O O   . ASN D 4 84  ? 129.970 95.504  78.867  1.00 35.66  ? 84  ASN N O   1 
ATOM   5416 C CB  . ASN D 4 84  ? 133.195 95.055  78.694  1.00 35.66  ? 84  ASN N CB  1 
ATOM   5417 C CG  . ASN D 4 84  ? 134.593 95.547  78.396  1.00 35.66  ? 84  ASN N CG  1 
ATOM   5418 O OD1 . ASN D 4 84  ? 134.937 96.689  78.692  1.00 35.66  ? 84  ASN N OD1 1 
ATOM   5419 N ND2 . ASN D 4 84  ? 135.411 94.682  77.810  1.00 35.66  ? 84  ASN N ND2 1 
ATOM   5420 N N   . SER D 4 85  ? 130.566 93.982  77.309  1.00 39.51  ? 85  SER N N   1 
ATOM   5421 C CA  . SER D 4 85  ? 129.369 93.159  77.462  1.00 39.51  ? 85  SER N CA  1 
ATOM   5422 C C   . SER D 4 85  ? 128.104 94.008  77.368  1.00 39.51  ? 85  SER N C   1 
ATOM   5423 O O   . SER D 4 85  ? 127.280 94.049  78.284  1.00 39.51  ? 85  SER N O   1 
ATOM   5424 C CB  . SER D 4 85  ? 129.412 92.391  78.783  1.00 39.51  ? 85  SER N CB  1 
ATOM   5425 O OG  . SER D 4 85  ? 129.355 93.276  79.886  1.00 39.51  ? 85  SER N OG  1 
ATOM   5426 N N   . LEU D 4 86  ? 127.953 94.694  76.239  1.00 37.03  ? 86  LEU N N   1 
ATOM   5427 C CA  . LEU D 4 86  ? 126.813 95.573  76.048  1.00 37.03  ? 86  LEU N CA  1 
ATOM   5428 C C   . LEU D 4 86  ? 125.539 94.764  75.817  1.00 37.03  ? 86  LEU N C   1 
ATOM   5429 O O   . LEU D 4 86  ? 125.572 93.573  75.499  1.00 37.03  ? 86  LEU N O   1 
ATOM   5430 C CB  . LEU D 4 86  ? 127.056 96.515  74.871  1.00 37.03  ? 86  LEU N CB  1 
ATOM   5431 C CG  . LEU D 4 86  ? 128.207 97.504  75.058  1.00 37.03  ? 86  LEU N CG  1 
ATOM   5432 C CD1 . LEU D 4 86  ? 128.520 98.200  73.752  1.00 37.03  ? 86  LEU N CD1 1 
ATOM   5433 C CD2 . LEU D 4 86  ? 127.875 98.518  76.133  1.00 37.03  ? 86  LEU N CD2 1 
ATOM   5434 N N   . LYS D 4 87  ? 124.408 95.434  75.983  1.00 35.83  ? 87  LYS N N   1 
ATOM   5435 C CA  . LYS D 4 87  ? 123.086 94.845  75.862  1.00 35.83  ? 87  LYS N CA  1 
ATOM   5436 C C   . LYS D 4 87  ? 122.209 95.742  75.007  1.00 35.83  ? 87  LYS N C   1 
ATOM   5437 O O   . LYS D 4 87  ? 122.537 96.911  74.779  1.00 35.83  ? 87  LYS N O   1 
ATOM   5438 C CB  . LYS D 4 87  ? 122.442 94.642  77.242  1.00 35.83  ? 87  LYS N CB  1 
ATOM   5439 N N   . PRO D 4 88  ? 121.083 95.224  74.507  1.00 36.92  ? 88  PRO N N   1 
ATOM   5440 C CA  . PRO D 4 88  ? 120.242 96.045  73.621  1.00 36.92  ? 88  PRO N CA  1 
ATOM   5441 C C   . PRO D 4 88  ? 119.801 97.359  74.241  1.00 36.92  ? 88  PRO N C   1 
ATOM   5442 O O   . PRO D 4 88  ? 119.698 98.364  73.528  1.00 36.92  ? 88  PRO N O   1 
ATOM   5443 C CB  . PRO D 4 88  ? 119.047 95.127  73.330  1.00 36.92  ? 88  PRO N CB  1 
ATOM   5444 C CG  . PRO D 4 88  ? 119.563 93.752  73.534  1.00 36.92  ? 88  PRO N CG  1 
ATOM   5445 C CD  . PRO D 4 88  ? 120.570 93.850  74.640  1.00 36.92  ? 88  PRO N CD  1 
ATOM   5446 N N   . GLU D 4 89  ? 119.536 97.387  75.549  1.00 37.55  ? 89  GLU N N   1 
ATOM   5447 C CA  . GLU D 4 89  ? 119.065 98.597  76.217  1.00 37.55  ? 89  GLU N CA  1 
ATOM   5448 C C   . GLU D 4 89  ? 120.206 99.464  76.736  1.00 37.55  ? 89  GLU N C   1 
ATOM   5449 O O   . GLU D 4 89  ? 120.007 100.250 77.673  1.00 37.55  ? 89  GLU N O   1 
ATOM   5450 C CB  . GLU D 4 89  ? 118.109 98.237  77.355  1.00 37.55  ? 89  GLU N CB  1 
ATOM   5451 C CG  . GLU D 4 89  ? 118.716 97.388  78.457  1.00 37.55  ? 89  GLU N CG  1 
ATOM   5452 C CD  . GLU D 4 89  ? 117.676 96.565  79.191  1.00 37.55  ? 89  GLU N CD  1 
ATOM   5453 O OE1 . GLU D 4 89  ? 116.757 96.039  78.530  1.00 37.55  ? 89  GLU N OE1 1 
ATOM   5454 O OE2 . GLU D 4 89  ? 117.777 96.445  80.430  1.00 37.55  ? 89  GLU N OE2 1 
ATOM   5455 N N   . ASP D 4 90  ? 121.398 99.338  76.157  1.00 33.15  ? 90  ASP N N   1 
ATOM   5456 C CA  . ASP D 4 90  ? 122.491 100.264 76.415  1.00 33.15  ? 90  ASP N CA  1 
ATOM   5457 C C   . ASP D 4 90  ? 122.477 101.457 75.471  1.00 33.15  ? 90  ASP N C   1 
ATOM   5458 O O   . ASP D 4 90  ? 123.276 102.382 75.652  1.00 33.15  ? 90  ASP N O   1 
ATOM   5459 C CB  . ASP D 4 90  ? 123.839 99.542  76.293  1.00 33.15  ? 90  ASP N CB  1 
ATOM   5460 C CG  . ASP D 4 90  ? 124.272 98.883  77.589  1.00 33.15  ? 90  ASP N CG  1 
ATOM   5461 O OD1 . ASP D 4 90  ? 123.552 99.012  78.600  1.00 33.15  ? 90  ASP N OD1 1 
ATOM   5462 O OD2 . ASP D 4 90  ? 125.336 98.230  77.596  1.00 33.15  ? 90  ASP N OD2 1 
ATOM   5463 N N   . THR D 4 91  ? 121.596 101.458 74.475  1.00 31.07  ? 91  THR N N   1 
ATOM   5464 C CA  . THR D 4 91  ? 121.535 102.549 73.513  1.00 31.07  ? 91  THR N CA  1 
ATOM   5465 C C   . THR D 4 91  ? 121.054 103.818 74.200  1.00 31.07  ? 91  THR N C   1 
ATOM   5466 O O   . THR D 4 91  ? 119.941 103.860 74.733  1.00 31.07  ? 91  THR N O   1 
ATOM   5467 C CB  . THR D 4 91  ? 120.601 102.184 72.362  1.00 31.07  ? 91  THR N CB  1 
ATOM   5468 O OG1 . THR D 4 91  ? 121.053 100.975 71.743  1.00 31.07  ? 91  THR N OG1 1 
ATOM   5469 C CG2 . THR D 4 91  ? 120.565 103.297 71.330  1.00 31.07  ? 91  THR N CG2 1 
ATOM   5470 N N   . ALA D 4 92  ? 121.888 104.855 74.184  1.00 26.99  ? 92  ALA N N   1 
ATOM   5471 C CA  . ALA D 4 92  ? 121.539 106.126 74.799  1.00 26.99  ? 92  ALA N CA  1 
ATOM   5472 C C   . ALA D 4 92  ? 122.672 107.107 74.546  1.00 26.99  ? 92  ALA N C   1 
ATOM   5473 O O   . ALA D 4 92  ? 123.802 106.711 74.249  1.00 26.99  ? 92  ALA N O   1 
ATOM   5474 C CB  . ALA D 4 92  ? 121.294 105.983 76.301  1.00 26.99  ? 92  ALA N CB  1 
ATOM   5475 N N   . VAL D 4 93  ? 122.353 108.396 74.667  1.00 26.05  ? 93  VAL N N   1 
ATOM   5476 C CA  . VAL D 4 93  ? 123.388 109.418 74.674  1.00 26.05  ? 93  VAL N CA  1 
ATOM   5477 C C   . VAL D 4 93  ? 124.089 109.391 76.025  1.00 26.05  ? 93  VAL N C   1 
ATOM   5478 O O   . VAL D 4 93  ? 123.488 109.063 77.055  1.00 26.05  ? 93  VAL N O   1 
ATOM   5479 C CB  . VAL D 4 93  ? 122.794 110.808 74.386  1.00 26.05  ? 93  VAL N CB  1 
ATOM   5480 C CG1 . VAL D 4 93  ? 123.888 111.860 74.359  1.00 26.05  ? 93  VAL N CG1 1 
ATOM   5481 C CG2 . VAL D 4 93  ? 122.029 110.806 73.072  1.00 26.05  ? 93  VAL N CG2 1 
ATOM   5482 N N   . TYR D 4 94  ? 125.379 109.726 76.027  1.00 25.90  ? 94  TYR N N   1 
ATOM   5483 C CA  . TYR D 4 94  ? 126.195 109.680 77.236  1.00 25.90  ? 94  TYR N CA  1 
ATOM   5484 C C   . TYR D 4 94  ? 126.860 111.035 77.434  1.00 25.90  ? 94  TYR N C   1 
ATOM   5485 O O   . TYR D 4 94  ? 127.686 111.448 76.616  1.00 25.90  ? 94  TYR N O   1 
ATOM   5486 C CB  . TYR D 4 94  ? 127.235 108.566 77.147  1.00 25.90  ? 94  TYR N CB  1 
ATOM   5487 C CG  . TYR D 4 94  ? 126.653 107.199 77.412  1.00 25.90  ? 94  TYR N CG  1 
ATOM   5488 C CD1 . TYR D 4 94  ? 125.752 106.628 76.527  1.00 25.90  ? 94  TYR N CD1 1 
ATOM   5489 C CD2 . TYR D 4 94  ? 126.993 106.485 78.551  1.00 25.90  ? 94  TYR N CD2 1 
ATOM   5490 C CE1 . TYR D 4 94  ? 125.210 105.383 76.764  1.00 25.90  ? 94  TYR N CE1 1 
ATOM   5491 C CE2 . TYR D 4 94  ? 126.455 105.239 78.795  1.00 25.90  ? 94  TYR N CE2 1 
ATOM   5492 C CZ  . TYR D 4 94  ? 125.565 104.693 77.897  1.00 25.90  ? 94  TYR N CZ  1 
ATOM   5493 O OH  . TYR D 4 94  ? 125.025 103.453 78.135  1.00 25.90  ? 94  TYR N OH  1 
ATOM   5494 N N   . TYR D 4 95  ? 126.510 111.712 78.523  1.00 24.79  ? 95  TYR N N   1 
ATOM   5495 C CA  . TYR D 4 95  ? 127.041 113.032 78.832  1.00 24.79  ? 95  TYR N CA  1 
ATOM   5496 C C   . TYR D 4 95  ? 128.110 112.917 79.908  1.00 24.79  ? 95  TYR N C   1 
ATOM   5497 O O   . TYR D 4 95  ? 127.875 112.321 80.963  1.00 24.79  ? 95  TYR N O   1 
ATOM   5498 C CB  . TYR D 4 95  ? 125.942 113.977 79.318  1.00 24.79  ? 95  TYR N CB  1 
ATOM   5499 C CG  . TYR D 4 95  ? 124.673 113.974 78.500  1.00 24.79  ? 95  TYR N CG  1 
ATOM   5500 C CD1 . TYR D 4 95  ? 123.632 113.112 78.805  1.00 24.79  ? 95  TYR N CD1 1 
ATOM   5501 C CD2 . TYR D 4 95  ? 124.512 114.846 77.434  1.00 24.79  ? 95  TYR N CD2 1 
ATOM   5502 C CE1 . TYR D 4 95  ? 122.470 113.114 78.067  1.00 24.79  ? 95  TYR N CE1 1 
ATOM   5503 C CE2 . TYR D 4 95  ? 123.354 114.852 76.689  1.00 24.79  ? 95  TYR N CE2 1 
ATOM   5504 C CZ  . TYR D 4 95  ? 122.336 113.985 77.010  1.00 24.79  ? 95  TYR N CZ  1 
ATOM   5505 O OH  . TYR D 4 95  ? 121.177 113.988 76.270  1.00 24.79  ? 95  TYR N OH  1 
ATOM   5506 N N   . CYS D 4 96  ? 129.275 113.494 79.641  1.00 23.24  ? 96  CYS N N   1 
ATOM   5507 C CA  . CYS D 4 96  ? 130.296 113.637 80.668  1.00 23.24  ? 96  CYS N CA  1 
ATOM   5508 C C   . CYS D 4 96  ? 129.949 114.812 81.572  1.00 23.24  ? 96  CYS N C   1 
ATOM   5509 O O   . CYS D 4 96  ? 129.810 115.947 81.113  1.00 23.24  ? 96  CYS N O   1 
ATOM   5510 C CB  . CYS D 4 96  ? 131.658 113.852 80.014  1.00 23.24  ? 96  CYS N CB  1 
ATOM   5511 S SG  . CYS D 4 96  ? 133.068 113.839 81.121  1.00 23.24  ? 96  CYS N SG  1 
ATOM   5512 N N   . ALA D 4 97  ? 129.808 114.536 82.868  1.00 22.05  ? 97  ALA N N   1 
ATOM   5513 C CA  . ALA D 4 97  ? 129.290 115.518 83.808  1.00 22.05  ? 97  ALA N CA  1 
ATOM   5514 C C   . ALA D 4 97  ? 130.377 115.930 84.786  1.00 22.05  ? 97  ALA N C   1 
ATOM   5515 O O   . ALA D 4 97  ? 131.304 115.169 85.070  1.00 22.05  ? 97  ALA N O   1 
ATOM   5516 C CB  . ALA D 4 97  ? 128.081 114.977 84.580  1.00 22.05  ? 97  ALA N CB  1 
ATOM   5517 N N   . ARG D 4 98  ? 130.252 117.154 85.292  1.00 16.77  ? 98  ARG N N   1 
ATOM   5518 C CA  . ARG D 4 98  ? 131.157 117.712 86.285  1.00 16.77  ? 98  ARG N CA  1 
ATOM   5519 C C   . ARG D 4 98  ? 130.340 118.115 87.500  1.00 16.77  ? 98  ARG N C   1 
ATOM   5520 O O   . ARG D 4 98  ? 129.142 118.384 87.389  1.00 16.77  ? 98  ARG N O   1 
ATOM   5521 C CB  . ARG D 4 98  ? 131.915 118.922 85.737  1.00 16.77  ? 98  ARG N CB  1 
ATOM   5522 C CG  . ARG D 4 98  ? 133.154 119.290 86.534  1.00 16.77  ? 98  ARG N CG  1 
ATOM   5523 C CD  . ARG D 4 98  ? 133.429 120.780 86.491  1.00 16.77  ? 98  ARG N CD  1 
ATOM   5524 N NE  . ARG D 4 98  ? 132.441 121.530 87.256  1.00 16.77  ? 98  ARG N NE  1 
ATOM   5525 C CZ  . ARG D 4 98  ? 132.367 122.852 87.292  1.00 16.77  ? 98  ARG N CZ  1 
ATOM   5526 N NH1 . ARG D 4 98  ? 133.218 123.611 86.622  1.00 16.77  ? 98  ARG N NH1 1 
ATOM   5527 N NH2 . ARG D 4 98  ? 131.417 123.428 88.022  1.00 16.77  ? 98  ARG N NH2 1 
ATOM   5528 N N   . CYS D 4 99  ? 130.986 118.161 88.658  1.00 16.99  ? 99  CYS N N   1 
ATOM   5529 C CA  . CYS D 4 99  ? 130.246 118.322 89.895  1.00 16.99  ? 99  CYS N CA  1 
ATOM   5530 C C   . CYS D 4 99  ? 130.313 119.788 90.330  1.00 16.99  ? 99  CYS N C   1 
ATOM   5531 O O   . CYS D 4 99  ? 131.369 120.419 90.234  1.00 16.99  ? 99  CYS N O   1 
ATOM   5532 C CB  . CYS D 4 99  ? 130.833 117.389 90.950  1.00 16.99  ? 99  CYS N CB  1 
ATOM   5533 S SG  . CYS D 4 99  ? 130.009 117.352 92.534  1.00 16.99  ? 99  CYS N SG  1 
ATOM   5534 N N   . PRO D 4 100 ? 129.203 120.363 90.807  1.00 13.66  ? 100 PRO N N   1 
ATOM   5535 C CA  . PRO D 4 100 ? 129.097 121.834 90.819  1.00 13.66  ? 100 PRO N CA  1 
ATOM   5536 C C   . PRO D 4 100 ? 130.198 122.562 91.576  1.00 13.66  ? 100 PRO N C   1 
ATOM   5537 O O   . PRO D 4 100 ? 130.566 123.667 91.163  1.00 13.66  ? 100 PRO N O   1 
ATOM   5538 C CB  . PRO D 4 100 ? 127.722 122.085 91.460  1.00 13.66  ? 100 PRO N CB  1 
ATOM   5539 C CG  . PRO D 4 100 ? 127.341 120.809 92.108  1.00 13.66  ? 100 PRO N CG  1 
ATOM   5540 C CD  . PRO D 4 100 ? 127.958 119.737 91.280  1.00 13.66  ? 100 PRO N CD  1 
ATOM   5541 N N   . ALA D 4 101 ? 130.730 122.005 92.659  1.00 14.76  ? 101 ALA N N   1 
ATOM   5542 C CA  . ALA D 4 101 ? 131.682 122.734 93.484  1.00 14.76  ? 101 ALA N CA  1 
ATOM   5543 C C   . ALA D 4 101 ? 132.915 121.891 93.774  1.00 14.76  ? 101 ALA N C   1 
ATOM   5544 O O   . ALA D 4 101 ? 132.844 120.659 93.772  1.00 14.76  ? 101 ALA N O   1 
ATOM   5545 C CB  . ALA D 4 101 ? 131.043 123.164 94.811  1.00 14.76  ? 101 ALA N CB  1 
ATOM   5546 N N   . PRO D 4 102 ? 134.058 122.527 94.028  1.00 14.15  ? 102 PRO N N   1 
ATOM   5547 C CA  . PRO D 4 102 ? 135.274 121.770 94.340  1.00 14.15  ? 102 PRO N CA  1 
ATOM   5548 C C   . PRO D 4 102 ? 135.430 121.536 95.835  1.00 14.15  ? 102 PRO N C   1 
ATOM   5549 O O   . PRO D 4 102 ? 134.808 122.187 96.675  1.00 14.15  ? 102 PRO N O   1 
ATOM   5550 C CB  . PRO D 4 102 ? 136.382 122.674 93.803  1.00 14.15  ? 102 PRO N CB  1 
ATOM   5551 C CG  . PRO D 4 102 ? 135.854 124.035 94.033  1.00 14.15  ? 102 PRO N CG  1 
ATOM   5552 C CD  . PRO D 4 102 ? 134.361 123.952 93.805  1.00 14.15  ? 102 PRO N CD  1 
ATOM   5553 N N   . PHE D 4 103 ? 136.285 120.563 96.156  1.00 16.76  ? 103 PHE N N   1 
ATOM   5554 C CA  . PHE D 4 103 ? 136.682 120.274 97.531  1.00 16.76  ? 103 PHE N CA  1 
ATOM   5555 C C   . PHE D 4 103 ? 135.538 119.716 98.367  1.00 16.76  ? 103 PHE N C   1 
ATOM   5556 O O   . PHE D 4 103 ? 135.729 119.406 99.547  1.00 16.76  ? 103 PHE N O   1 
ATOM   5557 C CB  . PHE D 4 103 ? 137.239 121.528 98.209  1.00 16.76  ? 103 PHE N CB  1 
ATOM   5558 C CG  . PHE D 4 103 ? 138.453 122.094 97.537  1.00 16.76  ? 103 PHE N CG  1 
ATOM   5559 C CD1 . PHE D 4 103 ? 139.565 121.305 97.305  1.00 16.76  ? 103 PHE N CD1 1 
ATOM   5560 C CD2 . PHE D 4 103 ? 138.489 123.422 97.150  1.00 16.76  ? 103 PHE N CD2 1 
ATOM   5561 C CE1 . PHE D 4 103 ? 140.683 121.825 96.690  1.00 16.76  ? 103 PHE N CE1 1 
ATOM   5562 C CE2 . PHE D 4 103 ? 139.606 123.948 96.535  1.00 16.76  ? 103 PHE N CE2 1 
ATOM   5563 C CZ  . PHE D 4 103 ? 140.704 123.148 96.306  1.00 16.76  ? 103 PHE N CZ  1 
ATOM   5564 N N   . THR D 4 104 ? 134.355 119.576 97.780  1.00 17.26  ? 104 THR N N   1 
ATOM   5565 C CA  . THR D 4 104 ? 133.190 119.160 98.542  1.00 17.26  ? 104 THR N CA  1 
ATOM   5566 C C   . THR D 4 104 ? 132.826 117.714 98.225  1.00 17.26  ? 104 THR N C   1 
ATOM   5567 O O   . THR D 4 104 ? 133.270 117.135 97.231  1.00 17.26  ? 104 THR N O   1 
ATOM   5568 C CB  . THR D 4 104 ? 132.001 120.070 98.245  1.00 17.26  ? 104 THR N CB  1 
ATOM   5569 O OG1 . THR D 4 104 ? 130.936 119.779 99.159  1.00 17.26  ? 104 THR N OG1 1 
ATOM   5570 C CG2 . THR D 4 104 ? 131.511 119.874 96.817  1.00 17.26  ? 104 THR N CG2 1 
ATOM   5571 N N   . ARG D 4 105 ? 132.001 117.131 99.096  1.00 19.15  ? 105 ARG N N   1 
ATOM   5572 C CA  . ARG D 4 105 ? 131.487 115.785 98.872  1.00 19.15  ? 105 ARG N CA  1 
ATOM   5573 C C   . ARG D 4 105 ? 130.081 115.802 98.289  1.00 19.15  ? 105 ARG N C   1 
ATOM   5574 O O   . ARG D 4 105 ? 129.785 115.035 97.368  1.00 19.15  ? 105 ARG N O   1 
ATOM   5575 C CB  . ARG D 4 105 ? 131.493 114.988 100.178 1.00 19.15  ? 105 ARG N CB  1 
ATOM   5576 C CG  . ARG D 4 105 ? 132.870 114.496 100.596 1.00 19.15  ? 105 ARG N CG  1 
ATOM   5577 C CD  . ARG D 4 105 ? 133.669 115.577 101.313 1.00 19.15  ? 105 ARG N CD  1 
ATOM   5578 N NE  . ARG D 4 105 ? 133.029 116.027 102.544 1.00 19.15  ? 105 ARG N NE  1 
ATOM   5579 C CZ  . ARG D 4 105 ? 132.783 115.255 103.596 1.00 19.15  ? 105 ARG N CZ  1 
ATOM   5580 N NH1 . ARG D 4 105 ? 133.182 113.994 103.640 1.00 19.15  ? 105 ARG N NH1 1 
ATOM   5581 N NH2 . ARG D 4 105 ? 132.135 115.766 104.639 1.00 19.15  ? 105 ARG N NH2 1 
ATOM   5582 N N   . ASP D 4 106 ? 129.207 116.661 98.806  1.00 18.39  ? 106 ASP N N   1 
ATOM   5583 C CA  . ASP D 4 106 ? 127.882 116.814 98.227  1.00 18.39  ? 106 ASP N CA  1 
ATOM   5584 C C   . ASP D 4 106 ? 127.988 117.236 96.766  1.00 18.39  ? 106 ASP N C   1 
ATOM   5585 O O   . ASP D 4 106 ? 128.811 118.077 96.395  1.00 18.39  ? 106 ASP N O   1 
ATOM   5586 C CB  . ASP D 4 106 ? 127.066 117.828 99.033  1.00 18.39  ? 106 ASP N CB  1 
ATOM   5587 C CG  . ASP D 4 106 ? 127.671 119.220 99.022  1.00 18.39  ? 106 ASP N CG  1 
ATOM   5588 O OD1 . ASP D 4 106 ? 128.751 119.410 98.427  1.00 18.39  ? 106 ASP N OD1 1 
ATOM   5589 O OD2 . ASP D 4 106 ? 127.061 120.132 99.615  1.00 18.39  ? 106 ASP N OD2 1 
ATOM   5590 N N   . CYS D 4 107 ? 127.154 116.625 95.922  1.00 15.20  ? 107 CYS N N   1 
ATOM   5591 C CA  . CYS D 4 107 ? 127.273 116.780 94.478  1.00 15.20  ? 107 CYS N CA  1 
ATOM   5592 C C   . CYS D 4 107 ? 125.892 116.996 93.849  1.00 15.20  ? 107 CYS N C   1 
ATOM   5593 O O   . CYS D 4 107 ? 125.495 116.329 92.901  1.00 15.20  ? 107 CYS N O   1 
ATOM   5594 C CB  . CYS D 4 107 ? 127.982 115.572 93.875  1.00 15.20  ? 107 CYS N CB  1 
ATOM   5595 S SG  . CYS D 4 107 ? 128.616 115.894 92.236  1.00 15.20  ? 107 CYS N SG  1 
ATOM   5596 N N   . PHE D 4 108 ? 125.146 117.948 94.402  1.00 14.54  ? 108 PHE N N   1 
ATOM   5597 C CA  . PHE D 4 108 ? 123.788 118.226 93.958  1.00 14.54  ? 108 PHE N CA  1 
ATOM   5598 C C   . PHE D 4 108 ? 123.714 118.477 92.452  1.00 14.54  ? 108 PHE N C   1 
ATOM   5599 O O   . PHE D 4 108 ? 124.679 118.897 91.809  1.00 14.54  ? 108 PHE N O   1 
ATOM   5600 C CB  . PHE D 4 108 ? 123.239 119.460 94.672  1.00 14.54  ? 108 PHE N CB  1 
ATOM   5601 C CG  . PHE D 4 108 ? 122.524 119.166 95.955  1.00 14.54  ? 108 PHE N CG  1 
ATOM   5602 C CD1 . PHE D 4 108 ? 121.216 118.719 95.947  1.00 14.54  ? 108 PHE N CD1 1 
ATOM   5603 C CD2 . PHE D 4 108 ? 123.147 119.376 97.169  1.00 14.54  ? 108 PHE N CD2 1 
ATOM   5604 C CE1 . PHE D 4 108 ? 120.555 118.465 97.126  1.00 14.54  ? 108 PHE N CE1 1 
ATOM   5605 C CE2 . PHE D 4 108 ? 122.489 119.124 98.350  1.00 14.54  ? 108 PHE N CE2 1 
ATOM   5606 C CZ  . PHE D 4 108 ? 121.191 118.670 98.328  1.00 14.54  ? 108 PHE N CZ  1 
ATOM   5607 N N   . ASP D 4 109 ? 122.531 118.205 91.897  1.00 15.88  ? 109 ASP N N   1 
ATOM   5608 C CA  . ASP D 4 109 ? 122.063 118.790 90.642  1.00 15.88  ? 109 ASP N CA  1 
ATOM   5609 C C   . ASP D 4 109 ? 122.756 118.285 89.382  1.00 15.88  ? 109 ASP N C   1 
ATOM   5610 O O   . ASP D 4 109 ? 122.568 118.863 88.309  1.00 15.88  ? 109 ASP N O   1 
ATOM   5611 C CB  . ASP D 4 109 ? 122.201 120.313 90.698  1.00 15.88  ? 109 ASP N CB  1 
ATOM   5612 C CG  . ASP D 4 109 ? 121.279 120.944 91.721  1.00 15.88  ? 109 ASP N CG  1 
ATOM   5613 O OD1 . ASP D 4 109 ? 120.389 120.237 92.236  1.00 15.88  ? 109 ASP N OD1 1 
ATOM   5614 O OD2 . ASP D 4 109 ? 121.442 122.148 92.004  1.00 15.88  ? 109 ASP N OD2 1 
ATOM   5615 N N   . VAL D 4 110 ? 123.545 117.215 89.475  1.00 14.82  ? 110 VAL N N   1 
ATOM   5616 C CA  . VAL D 4 110 ? 124.189 116.701 88.268  1.00 14.82  ? 110 VAL N CA  1 
ATOM   5617 C C   . VAL D 4 110 ? 123.154 116.151 87.297  1.00 14.82  ? 110 VAL N C   1 
ATOM   5618 O O   . VAL D 4 110 ? 123.336 116.222 86.077  1.00 14.82  ? 110 VAL N O   1 
ATOM   5619 C CB  . VAL D 4 110 ? 125.243 115.639 88.628  1.00 14.82  ? 110 VAL N CB  1 
ATOM   5620 C CG1 . VAL D 4 110 ? 126.247 116.209 89.608  1.00 14.82  ? 110 VAL N CG1 1 
ATOM   5621 C CG2 . VAL D 4 110 ? 124.578 114.402 89.197  1.00 14.82  ? 110 VAL N CG2 1 
ATOM   5622 N N   . THR D 4 111 ? 122.057 115.600 87.812  1.00 14.63  ? 111 THR N N   1 
ATOM   5623 C CA  . THR D 4 111 ? 121.052 114.961 86.974  1.00 14.63  ? 111 THR N CA  1 
ATOM   5624 C C   . THR D 4 111 ? 119.982 115.921 86.472  1.00 14.63  ? 111 THR N C   1 
ATOM   5625 O O   . THR D 4 111 ? 119.079 115.485 85.752  1.00 14.63  ? 111 THR N O   1 
ATOM   5626 C CB  . THR D 4 111 ? 120.375 113.823 87.742  1.00 14.63  ? 111 THR N CB  1 
ATOM   5627 O OG1 . THR D 4 111 ? 119.458 113.141 86.881  1.00 14.63  ? 111 THR N OG1 1 
ATOM   5628 C CG2 . THR D 4 111 ? 119.618 114.356 88.950  1.00 14.63  ? 111 THR N CG2 1 
ATOM   5629 N N   . SER D 4 112 ? 120.054 117.202 86.829  1.00 16.46  ? 112 SER N N   1 
ATOM   5630 C CA  . SER D 4 112 ? 118.973 118.125 86.521  1.00 16.46  ? 112 SER N CA  1 
ATOM   5631 C C   . SER D 4 112 ? 118.699 118.163 85.021  1.00 16.46  ? 112 SER N C   1 
ATOM   5632 O O   . SER D 4 112 ? 119.519 117.749 84.197  1.00 16.46  ? 112 SER N O   1 
ATOM   5633 C CB  . SER D 4 112 ? 119.310 119.529 87.019  1.00 16.46  ? 112 SER N CB  1 
ATOM   5634 O OG  . SER D 4 112 ? 120.396 120.076 86.295  1.00 16.46  ? 112 SER N OG  1 
ATOM   5635 N N   . THR D 4 113 ? 117.515 118.673 84.673  1.00 17.04  ? 113 THR N N   1 
ATOM   5636 C CA  . THR D 4 113 ? 117.115 118.729 83.271  1.00 17.04  ? 113 THR N CA  1 
ATOM   5637 C C   . THR D 4 113 ? 117.902 119.779 82.501  1.00 17.04  ? 113 THR N C   1 
ATOM   5638 O O   . THR D 4 113 ? 117.978 119.713 81.269  1.00 17.04  ? 113 THR N O   1 
ATOM   5639 C CB  . THR D 4 113 ? 115.620 119.022 83.163  1.00 17.04  ? 113 THR N CB  1 
ATOM   5640 O OG1 . THR D 4 113 ? 114.897 118.184 84.073  1.00 17.04  ? 113 THR N OG1 1 
ATOM   5641 C CG2 . THR D 4 113 ? 115.129 118.773 81.748  1.00 17.04  ? 113 THR N CG2 1 
ATOM   5642 N N   . THR D 4 114 ? 118.479 120.755 83.195  1.00 16.98  ? 114 THR N N   1 
ATOM   5643 C CA  . THR D 4 114 ? 119.202 121.849 82.562  1.00 16.98  ? 114 THR N CA  1 
ATOM   5644 C C   . THR D 4 114 ? 120.491 122.154 83.310  1.00 16.98  ? 114 THR N C   1 
ATOM   5645 O O   . THR D 4 114 ? 120.826 123.314 83.560  1.00 16.98  ? 114 THR N O   1 
ATOM   5646 C CB  . THR D 4 114 ? 118.330 123.097 82.476  1.00 16.98  ? 114 THR N CB  1 
ATOM   5647 O OG1 . THR D 4 114 ? 117.940 123.502 83.794  1.00 16.98  ? 114 THR N OG1 1 
ATOM   5648 C CG2 . THR D 4 114 ? 117.089 122.822 81.645  1.00 16.98  ? 114 THR N CG2 1 
ATOM   5649 N N   . TYR D 4 115 ? 121.238 121.117 83.680  1.00 14.06  ? 115 TYR N N   1 
ATOM   5650 C CA  . TYR D 4 115 ? 122.528 121.331 84.318  1.00 14.06  ? 115 TYR N CA  1 
ATOM   5651 C C   . TYR D 4 115 ? 123.453 122.087 83.375  1.00 14.06  ? 115 TYR N C   1 
ATOM   5652 O O   . TYR D 4 115 ? 123.442 121.871 82.161  1.00 14.06  ? 115 TYR N O   1 
ATOM   5653 C CB  . TYR D 4 115 ? 123.150 119.994 84.715  1.00 14.06  ? 115 TYR N CB  1 
ATOM   5654 C CG  . TYR D 4 115 ? 124.303 120.114 85.679  1.00 14.06  ? 115 TYR N CG  1 
ATOM   5655 C CD1 . TYR D 4 115 ? 124.162 120.792 86.878  1.00 14.06  ? 115 TYR N CD1 1 
ATOM   5656 C CD2 . TYR D 4 115 ? 125.530 119.542 85.394  1.00 14.06  ? 115 TYR N CD2 1 
ATOM   5657 C CE1 . TYR D 4 115 ? 125.210 120.900 87.759  1.00 14.06  ? 115 TYR N CE1 1 
ATOM   5658 C CE2 . TYR D 4 115 ? 126.583 119.646 86.269  1.00 14.06  ? 115 TYR N CE2 1 
ATOM   5659 C CZ  . TYR D 4 115 ? 126.417 120.325 87.450  1.00 14.06  ? 115 TYR N CZ  1 
ATOM   5660 O OH  . TYR D 4 115 ? 127.465 120.431 88.327  1.00 14.06  ? 115 TYR N OH  1 
ATOM   5661 N N   . ALA D 4 116 ? 124.262 122.980 83.943  1.00 15.69  ? 116 ALA N N   1 
ATOM   5662 C CA  . ALA D 4 116 ? 125.047 123.914 83.145  1.00 15.69  ? 116 ALA N CA  1 
ATOM   5663 C C   . ALA D 4 116 ? 126.426 123.376 82.777  1.00 15.69  ? 116 ALA N C   1 
ATOM   5664 O O   . ALA D 4 116 ? 126.942 123.693 81.700  1.00 15.69  ? 116 ALA N O   1 
ATOM   5665 C CB  . ALA D 4 116 ? 125.197 125.237 83.896  1.00 15.69  ? 116 ALA N CB  1 
ATOM   5666 N N   . TYR D 4 117 ? 127.040 122.571 83.643  1.00 14.62  ? 117 TYR N N   1 
ATOM   5667 C CA  . TYR D 4 117 ? 128.391 122.070 83.426  1.00 14.62  ? 117 TYR N CA  1 
ATOM   5668 C C   . TYR D 4 117 ? 128.405 120.672 82.820  1.00 14.62  ? 117 TYR N C   1 
ATOM   5669 O O   . TYR D 4 117 ? 129.395 119.949 82.974  1.00 14.62  ? 117 TYR N O   1 
ATOM   5670 C CB  . TYR D 4 117 ? 129.167 122.076 84.741  1.00 14.62  ? 117 TYR N CB  1 
ATOM   5671 C CG  . TYR D 4 117 ? 128.961 123.323 85.569  1.00 14.62  ? 117 TYR N CG  1 
ATOM   5672 C CD1 . TYR D 4 117 ? 129.487 124.541 85.171  1.00 14.62  ? 117 TYR N CD1 1 
ATOM   5673 C CD2 . TYR D 4 117 ? 128.233 123.281 86.747  1.00 14.62  ? 117 TYR N CD2 1 
ATOM   5674 C CE1 . TYR D 4 117 ? 129.299 125.678 85.925  1.00 14.62  ? 117 TYR N CE1 1 
ATOM   5675 C CE2 . TYR D 4 117 ? 128.040 124.412 87.506  1.00 14.62  ? 117 TYR N CE2 1 
ATOM   5676 C CZ  . TYR D 4 117 ? 128.574 125.606 87.092  1.00 14.62  ? 117 TYR N CZ  1 
ATOM   5677 O OH  . TYR D 4 117 ? 128.379 126.734 87.849  1.00 14.62  ? 117 TYR N OH  1 
ATOM   5678 N N   . ARG D 4 118 ? 127.334 120.276 82.139  1.00 16.48  ? 118 ARG N N   1 
ATOM   5679 C CA  . ARG D 4 118 ? 127.236 118.950 81.546  1.00 16.48  ? 118 ARG N CA  1 
ATOM   5680 C C   . ARG D 4 118 ? 127.749 118.972 80.112  1.00 16.48  ? 118 ARG N C   1 
ATOM   5681 O O   . ARG D 4 118 ? 127.669 119.995 79.426  1.00 16.48  ? 118 ARG N O   1 
ATOM   5682 C CB  . ARG D 4 118 ? 125.791 118.456 81.576  1.00 16.48  ? 118 ARG N CB  1 
ATOM   5683 C CG  . ARG D 4 118 ? 125.639 116.969 81.332  1.00 16.48  ? 118 ARG N CG  1 
ATOM   5684 C CD  . ARG D 4 118 ? 124.383 116.431 81.984  1.00 16.48  ? 118 ARG N CD  1 
ATOM   5685 N NE  . ARG D 4 118 ? 123.180 117.016 81.405  1.00 16.48  ? 118 ARG N NE  1 
ATOM   5686 C CZ  . ARG D 4 118 ? 122.020 117.133 82.037  1.00 16.48  ? 118 ARG N CZ  1 
ATOM   5687 N NH1 . ARG D 4 118 ? 121.864 116.716 83.282  1.00 16.48  ? 118 ARG N NH1 1 
ATOM   5688 N NH2 . ARG D 4 118 ? 120.989 117.678 81.401  1.00 16.48  ? 118 ARG N NH2 1 
ATOM   5689 N N   . GLY D 4 119 ? 128.269 117.836 79.663  1.00 22.74  ? 119 GLY N N   1 
ATOM   5690 C CA  . GLY D 4 119 ? 128.871 117.744 78.352  1.00 22.74  ? 119 GLY N CA  1 
ATOM   5691 C C   . GLY D 4 119 ? 127.842 117.673 77.238  1.00 22.74  ? 119 GLY N C   1 
ATOM   5692 O O   . GLY D 4 119 ? 126.633 117.589 77.452  1.00 22.74  ? 119 GLY N O   1 
ATOM   5693 N N   . GLN D 4 120 ? 128.353 117.715 76.005  1.00 42.43  ? 120 GLN N N   1 
ATOM   5694 C CA  . GLN D 4 120 ? 127.479 117.695 74.837  1.00 42.43  ? 120 GLN N CA  1 
ATOM   5695 C C   . GLN D 4 120 ? 126.861 116.317 74.633  1.00 42.43  ? 120 GLN N C   1 
ATOM   5696 O O   . GLN D 4 120 ? 125.654 116.197 74.393  1.00 42.43  ? 120 GLN N O   1 
ATOM   5697 C CB  . GLN D 4 120 ? 128.262 118.121 73.595  1.00 42.43  ? 120 GLN N CB  1 
ATOM   5698 C CG  . GLN D 4 120 ? 127.460 118.953 72.608  1.00 42.43  ? 120 GLN N CG  1 
ATOM   5699 C CD  . GLN D 4 120 ? 126.967 120.256 73.207  1.00 42.43  ? 120 GLN N CD  1 
ATOM   5700 O OE1 . GLN D 4 120 ? 127.746 121.034 73.756  1.00 42.43  ? 120 GLN N OE1 1 
ATOM   5701 N NE2 . GLN D 4 120 ? 125.666 120.500 73.106  1.00 42.43  ? 120 GLN N NE2 1 
ATOM   5702 N N   . GLY D 4 121 ? 127.669 115.272 74.718  1.00 34.59  ? 121 GLY N N   1 
ATOM   5703 C CA  . GLY D 4 121 ? 127.194 113.908 74.636  1.00 34.59  ? 121 GLY N CA  1 
ATOM   5704 C C   . GLY D 4 121 ? 127.590 113.238 73.328  1.00 34.59  ? 121 GLY N C   1 
ATOM   5705 O O   . GLY D 4 121 ? 127.845 113.884 72.308  1.00 34.59  ? 121 GLY N O   1 
ATOM   5706 N N   . THR D 4 122 ? 127.640 111.907 73.377  1.00 29.71  ? 122 THR N N   1 
ATOM   5707 C CA  . THR D 4 122 ? 127.924 111.070 72.218  1.00 29.71  ? 122 THR N CA  1 
ATOM   5708 C C   . THR D 4 122 ? 126.934 109.916 72.201  1.00 29.71  ? 122 THR N C   1 
ATOM   5709 O O   . THR D 4 122 ? 126.668 109.310 73.244  1.00 29.71  ? 122 THR N O   1 
ATOM   5710 C CB  . THR D 4 122 ? 129.361 110.536 72.248  1.00 29.71  ? 122 THR N CB  1 
ATOM   5711 O OG1 . THR D 4 122 ? 129.580 109.684 71.118  1.00 29.71  ? 122 THR N OG1 1 
ATOM   5712 C CG2 . THR D 4 122 ? 129.624 109.752 73.525  1.00 29.71  ? 122 THR N CG2 1 
ATOM   5713 N N   . GLN D 4 123 ? 126.391 109.614 71.024  1.00 29.11  ? 123 GLN N N   1 
ATOM   5714 C CA  . GLN D 4 123 ? 125.349 108.600 70.896  1.00 29.11  ? 123 GLN N CA  1 
ATOM   5715 C C   . GLN D 4 123 ? 125.991 107.239 70.666  1.00 29.11  ? 123 GLN N C   1 
ATOM   5716 O O   . GLN D 4 123 ? 126.636 107.012 69.638  1.00 29.11  ? 123 GLN N O   1 
ATOM   5717 C CB  . GLN D 4 123 ? 124.400 108.958 69.756  1.00 29.11  ? 123 GLN N CB  1 
ATOM   5718 C CG  . GLN D 4 123 ? 123.351 107.895 69.436  1.00 29.11  ? 123 GLN N CG  1 
ATOM   5719 C CD  . GLN D 4 123 ? 122.374 107.658 70.574  1.00 29.11  ? 123 GLN N CD  1 
ATOM   5720 O OE1 . GLN D 4 123 ? 122.562 108.149 71.685  1.00 29.11  ? 123 GLN N OE1 1 
ATOM   5721 N NE2 . GLN D 4 123 ? 121.318 106.903 70.295  1.00 29.11  ? 123 GLN N NE2 1 
ATOM   5722 N N   . VAL D 4 124 ? 125.805 106.330 71.617  1.00 31.60  ? 124 VAL N N   1 
ATOM   5723 C CA  . VAL D 4 124 ? 126.289 104.959 71.514  1.00 31.60  ? 124 VAL N CA  1 
ATOM   5724 C C   . VAL D 4 124 ? 125.091 104.079 71.194  1.00 31.60  ? 124 VAL N C   1 
ATOM   5725 O O   . VAL D 4 124 ? 124.135 104.009 71.975  1.00 31.60  ? 124 VAL N O   1 
ATOM   5726 C CB  . VAL D 4 124 ? 126.986 104.505 72.804  1.00 31.60  ? 124 VAL N CB  1 
ATOM   5727 C CG1 . VAL D 4 124 ? 127.253 103.010 72.765  1.00 31.60  ? 124 VAL N CG1 1 
ATOM   5728 C CG2 . VAL D 4 124 ? 128.279 105.270 73.006  1.00 31.60  ? 124 VAL N CG2 1 
ATOM   5729 N N   . THR D 4 125 ? 125.137 103.405 70.050  1.00 36.32  ? 125 THR N N   1 
ATOM   5730 C CA  . THR D 4 125 ? 124.076 102.509 69.615  1.00 36.32  ? 125 THR N CA  1 
ATOM   5731 C C   . THR D 4 125 ? 124.594 101.080 69.600  1.00 36.32  ? 125 THR N C   1 
ATOM   5732 O O   . THR D 4 125 ? 125.751 100.833 69.247  1.00 36.32  ? 125 THR N O   1 
ATOM   5733 C CB  . THR D 4 125 ? 123.565 102.890 68.224  1.00 36.32  ? 125 THR N CB  1 
ATOM   5734 O OG1 . THR D 4 125 ? 123.186 104.272 68.211  1.00 36.32  ? 125 THR N OG1 1 
ATOM   5735 C CG2 . THR D 4 125 ? 122.366 102.037 67.843  1.00 36.32  ? 125 THR N CG2 1 
ATOM   5736 N N   . VAL D 4 126 ? 123.735 100.142 69.986  1.00 37.48  ? 126 VAL N N   1 
ATOM   5737 C CA  . VAL D 4 126 ? 124.125 98.740  70.062  1.00 37.48  ? 126 VAL N CA  1 
ATOM   5738 C C   . VAL D 4 126 ? 123.442 97.935  68.961  1.00 37.48  ? 126 VAL N C   1 
ATOM   5739 O O   . VAL D 4 126 ? 122.232 98.033  68.761  0.00 37.48  ? 126 VAL N O   1 
ATOM   5740 C CB  . VAL D 4 126 ? 123.801 98.150  71.441  1.00 37.48  ? 126 VAL N CB  1 
ATOM   5741 C CG1 . VAL D 4 126 ? 124.428 98.995  72.539  1.00 37.48  ? 126 VAL N CG1 1 
ATOM   5742 C CG2 . VAL D 4 126 ? 122.299 98.036  71.630  1.00 37.48  ? 126 VAL N CG2 1 
ATOM   5743 N N   . HIS E 5 1   ? 123.316 119.635 158.758 1.00 36.66  ? 7   HIS P N   1 
ATOM   5744 C CA  . HIS E 5 1   ? 124.539 119.635 157.913 1.00 36.66  ? 7   HIS P CA  1 
ATOM   5745 C C   . HIS E 5 1   ? 125.751 119.226 158.751 1.00 36.66  ? 7   HIS P C   1 
ATOM   5746 O O   . HIS E 5 1   ? 125.752 119.530 159.957 1.00 36.66  ? 7   HIS P O   1 
ATOM   5747 C CB  . HIS E 5 1   ? 124.737 121.002 157.249 1.00 36.66  ? 7   HIS P CB  1 
ATOM   5748 C CG  . HIS E 5 1   ? 124.309 122.158 158.086 1.00 36.66  ? 7   HIS P CG  1 
ATOM   5749 N ND1 . HIS E 5 1   ? 125.188 122.845 158.896 1.00 36.66  ? 7   HIS P ND1 1 
ATOM   5750 C CD2 . HIS E 5 1   ? 123.108 122.755 158.231 1.00 36.66  ? 7   HIS P CD2 1 
ATOM   5751 C CE1 . HIS E 5 1   ? 124.545 123.816 159.511 1.00 36.66  ? 7   HIS P CE1 1 
ATOM   5752 N NE2 . HIS E 5 1   ? 123.266 123.780 159.122 1.00 36.66  ? 7   HIS P NE2 1 
ATOM   5753 N N   . ALA E 5 2   ? 126.746 118.579 158.142 1.00 43.22  ? 8   ALA P N   1 
ATOM   5754 C CA  . ALA E 5 2   ? 127.977 118.133 158.833 1.00 43.22  ? 8   ALA P CA  1 
ATOM   5755 C C   . ALA E 5 2   ? 128.811 119.346 159.248 1.00 43.22  ? 8   ALA P C   1 
ATOM   5756 O O   . ALA E 5 2   ? 129.588 119.211 160.200 1.00 43.22  ? 8   ALA P O   1 
ATOM   5757 C CB  . ALA E 5 2   ? 128.770 117.231 157.929 1.00 43.22  ? 8   ALA P CB  1 
ATOM   5758 N N   . GLU E 5 3   ? 128.669 120.480 158.558 1.00 39.89  ? 9   GLU P N   1 
ATOM   5759 C CA  . GLU E 5 3   ? 129.443 121.711 158.858 1.00 39.89  ? 9   GLU P CA  1 
ATOM   5760 C C   . GLU E 5 3   ? 128.860 122.350 160.113 1.00 39.89  ? 9   GLU P C   1 
ATOM   5761 O O   . GLU E 5 3   ? 129.457 123.320 160.597 1.00 39.89  ? 9   GLU P O   1 
ATOM   5762 C CB  . GLU E 5 3   ? 129.401 122.683 157.680 1.00 39.89  ? 9   GLU P CB  1 
ATOM   5763 C CG  . GLU E 5 3   ? 130.309 122.291 156.529 1.00 39.89  ? 9   GLU P CG  1 
ATOM   5764 C CD  . GLU E 5 3   ? 129.793 121.164 155.651 1.00 39.89  ? 9   GLU P CD  1 
ATOM   5765 O OE1 . GLU E 5 3   ? 130.530 120.751 154.734 1.00 39.89  ? 9   GLU P OE1 1 
ATOM   5766 O OE2 . GLU E 5 3   ? 128.654 120.712 155.877 1.00 39.89  ? 9   GLU P OE2 1 
ATOM   5767 N N   . GLY E 5 4   ? 127.736 121.835 160.612 1.00 43.70  ? 10  GLY P N   1 
ATOM   5768 C CA  . GLY E 5 4   ? 127.064 122.391 161.799 1.00 43.70  ? 10  GLY P CA  1 
ATOM   5769 C C   . GLY E 5 4   ? 127.148 121.469 162.996 1.00 43.70  ? 10  GLY P C   1 
ATOM   5770 O O   . GLY E 5 4   ? 127.094 121.989 164.119 1.00 43.70  ? 10  GLY P O   1 
ATOM   5771 N N   . THR E 5 5   ? 127.340 120.160 162.813 1.00 46.91  ? 11  THR P N   1 
ATOM   5772 C CA  . THR E 5 5   ? 127.527 119.261 163.989 1.00 46.91  ? 11  THR P CA  1 
ATOM   5773 C C   . THR E 5 5   ? 128.983 119.323 164.465 1.00 46.91  ? 11  THR P C   1 
ATOM   5774 O O   . THR E 5 5   ? 129.228 119.332 165.706 1.00 46.91  ? 11  THR P O   1 
ATOM   5775 C CB  . THR E 5 5   ? 127.095 117.825 163.676 1.00 46.91  ? 11  THR P CB  1 
ATOM   5776 O OG1 . THR E 5 5   ? 125.794 117.632 164.231 1.00 46.91  ? 11  THR P OG1 1 
ATOM   5777 C CG2 . THR E 5 5   ? 128.050 116.790 164.227 1.00 46.91  ? 11  THR P CG2 1 
ATOM   5778 N N   . PHE E 5 6   ? 129.916 119.404 163.519 1.00 46.28  ? 12  PHE P N   1 
ATOM   5779 C CA  . PHE E 5 6   ? 131.347 119.446 163.896 1.00 46.28  ? 12  PHE P CA  1 
ATOM   5780 C C   . PHE E 5 6   ? 131.573 120.715 164.716 1.00 46.28  ? 12  PHE P C   1 
ATOM   5781 O O   . PHE E 5 6   ? 132.337 120.659 165.695 1.00 46.28  ? 12  PHE P O   1 
ATOM   5782 C CB  . PHE E 5 6   ? 132.238 119.390 162.652 1.00 46.28  ? 12  PHE P CB  1 
ATOM   5783 C CG  . PHE E 5 6   ? 133.680 119.780 162.857 1.00 46.28  ? 12  PHE P CG  1 
ATOM   5784 C CD1 . PHE E 5 6   ? 134.072 121.108 162.803 1.00 46.28  ? 12  PHE P CD1 1 
ATOM   5785 C CD2 . PHE E 5 6   ? 134.650 118.817 163.078 1.00 46.28  ? 12  PHE P CD2 1 
ATOM   5786 C CE1 . PHE E 5 6   ? 135.399 121.464 162.983 1.00 46.28  ? 12  PHE P CE1 1 
ATOM   5787 C CE2 . PHE E 5 6   ? 135.977 119.175 163.255 1.00 46.28  ? 12  PHE P CE2 1 
ATOM   5788 C CZ  . PHE E 5 6   ? 136.350 120.497 163.208 1.00 46.28  ? 12  PHE P CZ  1 
ATOM   5789 N N   . THR E 5 7   ? 130.955 121.830 164.314 1.00 48.37  ? 13  THR P N   1 
ATOM   5790 C CA  . THR E 5 7   ? 131.200 123.101 165.042 1.00 48.37  ? 13  THR P CA  1 
ATOM   5791 C C   . THR E 5 7   ? 130.706 122.965 166.482 1.00 48.37  ? 13  THR P C   1 
ATOM   5792 O O   . THR E 5 7   ? 131.439 123.390 167.395 1.00 48.37  ? 13  THR P O   1 
ATOM   5793 C CB  . THR E 5 7   ? 130.527 124.296 164.359 1.00 48.37  ? 13  THR P CB  1 
ATOM   5794 O OG1 . THR E 5 7   ? 131.245 124.579 163.158 1.00 48.37  ? 13  THR P OG1 1 
ATOM   5795 C CG2 . THR E 5 7   ? 130.491 125.528 165.235 1.00 48.37  ? 13  THR P CG2 1 
ATOM   5796 N N   . SER E 5 8   ? 129.544 122.338 166.675 1.00 55.46  ? 14  SER P N   1 
ATOM   5797 C CA  . SER E 5 8   ? 129.031 122.125 168.049 1.00 55.46  ? 14  SER P CA  1 
ATOM   5798 C C   . SER E 5 8   ? 129.977 121.224 168.843 1.00 55.46  ? 14  SER P C   1 
ATOM   5799 O O   . SER E 5 8   ? 130.280 121.566 170.014 1.00 55.46  ? 14  SER P O   1 
ATOM   5800 C CB  . SER E 5 8   ? 127.661 121.518 168.006 1.00 55.46  ? 14  SER P CB  1 
ATOM   5801 O OG  . SER E 5 8   ? 127.651 120.252 168.646 1.00 55.46  ? 14  SER P OG  1 
ATOM   5802 N N   . ASP E 5 9   ? 130.496 120.159 168.229 1.00 58.58  ? 15  ASP P N   1 
ATOM   5803 C CA  . ASP E 5 9   ? 131.424 119.346 169.052 1.00 58.58  ? 15  ASP P CA  1 
ATOM   5804 C C   . ASP E 5 9   ? 132.645 120.178 169.428 1.00 58.58  ? 15  ASP P C   1 
ATOM   5805 O O   . ASP E 5 9   ? 132.932 120.287 170.647 1.00 58.58  ? 15  ASP P O   1 
ATOM   5806 C CB  . ASP E 5 9   ? 131.861 118.086 168.309 1.00 58.58  ? 15  ASP P CB  1 
ATOM   5807 C CG  . ASP E 5 9   ? 130.705 117.169 167.950 1.00 58.58  ? 15  ASP P CG  1 
ATOM   5808 O OD1 . ASP E 5 9   ? 129.650 117.275 168.607 1.00 58.58  ? 15  ASP P OD1 1 
ATOM   5809 O OD2 . ASP E 5 9   ? 130.870 116.357 167.018 1.00 58.58  ? 15  ASP P OD2 1 
ATOM   5810 N N   . VAL E 5 10  ? 133.172 120.950 168.477 1.00 55.99  ? 16  VAL P N   1 
ATOM   5811 C CA  . VAL E 5 10  ? 134.443 121.653 168.804 1.00 55.99  ? 16  VAL P CA  1 
ATOM   5812 C C   . VAL E 5 10  ? 134.129 122.593 169.955 1.00 55.99  ? 16  VAL P C   1 
ATOM   5813 O O   . VAL E 5 10  ? 134.814 122.501 170.983 1.00 55.99  ? 16  VAL P O   1 
ATOM   5814 C CB  . VAL E 5 10  ? 134.990 122.435 167.600 1.00 55.99  ? 16  VAL P CB  1 
ATOM   5815 C CG1 . VAL E 5 10  ? 135.933 123.543 168.036 1.00 55.99  ? 16  VAL P CG1 1 
ATOM   5816 C CG2 . VAL E 5 10  ? 135.666 121.516 166.596 1.00 55.99  ? 16  VAL P CG2 1 
ATOM   5817 N N   . SER E 5 11  ? 132.978 123.254 169.880 1.00 64.59  ? 17  SER P N   1 
ATOM   5818 C CA  . SER E 5 11  ? 132.651 124.254 170.921 1.00 64.59  ? 17  SER P CA  1 
ATOM   5819 C C   . SER E 5 11  ? 132.526 123.547 172.263 1.00 64.59  ? 17  SER P C   1 
ATOM   5820 O O   . SER E 5 11  ? 133.317 123.875 173.153 1.00 64.59  ? 17  SER P O   1 
ATOM   5821 C CB  . SER E 5 11  ? 131.396 125.001 170.592 1.00 64.59  ? 17  SER P CB  1 
ATOM   5822 O OG  . SER E 5 11  ? 130.457 124.893 171.650 1.00 64.59  ? 17  SER P OG  1 
HETATM 5823 N N   . XCP E 5 12  ? 131.586 122.628 172.404 1.00 20.00  ? 18  XCP P N   1 
HETATM 5824 C CB  . XCP E 5 12  ? 131.419 121.924 173.652 1.00 20.00  ? 18  XCP P CB  1 
HETATM 5825 C CG  . XCP E 5 12  ? 129.952 121.611 173.912 1.00 20.00  ? 18  XCP P CG  1 
HETATM 5826 C CD  . XCP E 5 12  ? 129.910 120.252 174.604 1.00 20.00  ? 18  XCP P CD  1 
HETATM 5827 C CE  . XCP E 5 12  ? 131.316 119.660 174.578 1.00 20.00  ? 18  XCP P CE  1 
HETATM 5828 C CA  . XCP E 5 12  ? 132.147 120.565 173.679 1.00 20.00  ? 18  XCP P CA  1 
HETATM 5829 C C   . XCP E 5 12  ? 133.561 120.684 174.164 1.00 20.00  ? 18  XCP P C   1 
HETATM 5830 O O   . XCP E 5 12  ? 133.859 121.139 175.232 1.00 20.00  ? 18  XCP P O   1 
ATOM   5831 N N   . TYR E 5 13  ? 134.375 120.229 173.219 1.00 68.26  ? 19  TYR P N   1 
ATOM   5832 C CA  . TYR E 5 13  ? 135.839 120.207 173.466 1.00 68.26  ? 19  TYR P CA  1 
ATOM   5833 C C   . TYR E 5 13  ? 136.346 121.478 174.154 1.00 68.26  ? 19  TYR P C   1 
ATOM   5834 O O   . TYR E 5 13  ? 136.829 121.365 175.295 1.00 68.26  ? 19  TYR P O   1 
ATOM   5835 C CB  . TYR E 5 13  ? 136.617 119.959 172.174 1.00 68.26  ? 19  TYR P CB  1 
ATOM   5836 C CG  . TYR E 5 13  ? 138.077 119.680 172.415 1.00 68.26  ? 19  TYR P CG  1 
ATOM   5837 C CD1 . TYR E 5 13  ? 138.995 120.711 172.523 1.00 68.26  ? 19  TYR P CD1 1 
ATOM   5838 C CD2 . TYR E 5 13  ? 138.538 118.384 172.574 1.00 68.26  ? 19  TYR P CD2 1 
ATOM   5839 C CE1 . TYR E 5 13  ? 140.336 120.461 172.759 1.00 68.26  ? 19  TYR P CE1 1 
ATOM   5840 C CE2 . TYR E 5 13  ? 139.875 118.116 172.811 1.00 68.26  ? 19  TYR P CE2 1 
ATOM   5841 C CZ  . TYR E 5 13  ? 140.778 119.159 172.904 1.00 68.26  ? 19  TYR P CZ  1 
ATOM   5842 O OH  . TYR E 5 13  ? 142.097 118.903 173.138 1.00 68.26  ? 19  TYR P OH  1 
ATOM   5843 N N   . LEU E 5 14  ? 136.248 122.638 173.506 1.00 72.67  ? 20  LEU P N   1 
ATOM   5844 C CA  . LEU E 5 14  ? 136.874 123.871 174.060 1.00 72.67  ? 20  LEU P CA  1 
ATOM   5845 C C   . LEU E 5 14  ? 136.253 124.252 175.408 1.00 72.67  ? 20  LEU P C   1 
ATOM   5846 O O   . LEU E 5 14  ? 137.007 124.650 176.307 1.00 72.67  ? 20  LEU P O   1 
ATOM   5847 C CB  . LEU E 5 14  ? 136.746 124.974 173.007 1.00 72.67  ? 20  LEU P CB  1 
ATOM   5848 C CG  . LEU E 5 14  ? 137.355 124.601 171.656 1.00 72.67  ? 20  LEU P CG  1 
ATOM   5849 C CD1 . LEU E 5 14  ? 137.186 125.712 170.634 1.00 72.67  ? 20  LEU P CD1 1 
ATOM   5850 C CD2 . LEU E 5 14  ? 138.822 124.234 171.809 1.00 72.67  ? 20  LEU P CD2 1 
ATOM   5851 N N   . GLU E 5 15  ? 134.937 124.123 175.544 1.00 81.20  ? 21  GLU P N   1 
ATOM   5852 C CA  . GLU E 5 15  ? 134.255 124.528 176.798 1.00 81.20  ? 21  GLU P CA  1 
ATOM   5853 C C   . GLU E 5 15  ? 134.782 123.654 177.934 1.00 81.20  ? 21  GLU P C   1 
ATOM   5854 O O   . GLU E 5 15  ? 135.016 124.190 179.027 1.00 81.20  ? 21  GLU P O   1 
ATOM   5855 C CB  . GLU E 5 15  ? 132.741 124.371 176.659 1.00 81.20  ? 21  GLU P CB  1 
ATOM   5856 C CG  . GLU E 5 15  ? 131.954 125.357 177.500 1.00 81.20  ? 21  GLU P CG  1 
ATOM   5857 C CD  . GLU E 5 15  ? 131.515 126.606 176.757 1.00 81.20  ? 21  GLU P CD  1 
ATOM   5858 O OE1 . GLU E 5 15  ? 131.172 126.493 175.564 1.00 81.20  ? 21  GLU P OE1 1 
ATOM   5859 O OE2 . GLU E 5 15  ? 131.516 127.689 177.373 1.00 81.20  ? 21  GLU P OE2 1 
ATOM   5860 N N   . GLY E 5 16  ? 134.974 122.358 177.679 1.00 78.79  ? 22  GLY P N   1 
ATOM   5861 C CA  . GLY E 5 16  ? 135.564 121.512 178.734 1.00 78.79  ? 22  GLY P CA  1 
ATOM   5862 C C   . GLY E 5 16  ? 137.016 121.868 178.995 1.00 78.79  ? 22  GLY P C   1 
ATOM   5863 O O   . GLY E 5 16  ? 137.404 121.901 180.174 1.00 78.79  ? 22  GLY P O   1 
ATOM   5864 N N   . GLN E 5 17  ? 137.787 122.149 177.941 1.00 77.85  ? 23  GLN P N   1 
ATOM   5865 C CA  . GLN E 5 17  ? 139.245 122.416 178.080 1.00 77.85  ? 23  GLN P CA  1 
ATOM   5866 C C   . GLN E 5 17  ? 139.460 123.827 178.627 1.00 77.85  ? 23  GLN P C   1 
ATOM   5867 O O   . GLN E 5 17  ? 140.253 123.977 179.591 1.00 77.85  ? 23  GLN P O   1 
ATOM   5868 C CB  . GLN E 5 17  ? 139.953 122.261 176.737 1.00 77.85  ? 23  GLN P CB  1 
ATOM   5869 C CG  . GLN E 5 17  ? 141.180 123.147 176.592 1.00 77.85  ? 23  GLN P CG  1 
ATOM   5870 C CD  . GLN E 5 17  ? 142.331 122.663 177.439 1.00 77.85  ? 23  GLN P CD  1 
ATOM   5871 O OE1 . GLN E 5 17  ? 142.686 123.272 178.446 1.00 77.85  ? 23  GLN P OE1 1 
ATOM   5872 N NE2 . GLN E 5 17  ? 142.927 121.554 177.032 1.00 77.85  ? 23  GLN P NE2 1 
ATOM   5873 N N   . ALA E 5 18  ? 138.785 124.819 178.036 1.00 86.84  ? 24  ALA P N   1 
ATOM   5874 C CA  . ALA E 5 18  ? 138.907 126.175 178.558 1.00 86.84  ? 24  ALA P CA  1 
ATOM   5875 C C   . ALA E 5 18  ? 138.545 126.229 180.035 1.00 86.84  ? 24  ALA P C   1 
ATOM   5876 O O   . ALA E 5 18  ? 139.216 126.911 180.819 1.00 86.84  ? 24  ALA P O   1 
ATOM   5877 C CB  . ALA E 5 18  ? 138.026 127.125 177.749 1.00 86.84  ? 24  ALA P CB  1 
ATOM   5878 N N   . ALA E 5 19  ? 137.488 125.520 180.440 1.00 92.28  ? 25  ALA P N   1 
ATOM   5879 C CA  . ALA E 5 19  ? 137.116 125.502 181.851 1.00 92.28  ? 25  ALA P CA  1 
ATOM   5880 C C   . ALA E 5 19  ? 138.217 124.879 182.700 1.00 92.28  ? 25  ALA P C   1 
ATOM   5881 O O   . ALA E 5 19  ? 138.538 125.382 183.785 1.00 92.28  ? 25  ALA P O   1 
ATOM   5882 C CB  . ALA E 5 19  ? 135.802 124.745 182.038 1.00 92.28  ? 25  ALA P CB  1 
ATOM   5883 N N   . LYS E 5 20  ? 138.805 123.779 182.226 1.00 92.72  ? 26  LYS P N   1 
ATOM   5884 C CA  . LYS E 5 20  ? 139.883 123.140 182.971 1.00 92.72  ? 26  LYS P CA  1 
ATOM   5885 C C   . LYS E 5 20  ? 141.095 124.056 183.074 1.00 92.72  ? 26  LYS P C   1 
ATOM   5886 O O   . LYS E 5 20  ? 141.733 124.138 184.130 1.00 92.72  ? 26  LYS P O   1 
ATOM   5887 C CB  . LYS E 5 20  ? 140.259 121.815 182.310 1.00 92.72  ? 26  LYS P CB  1 
ATOM   5888 C CG  . LYS E 5 20  ? 139.179 120.748 182.427 1.00 92.72  ? 26  LYS P CG  1 
ATOM   5889 C CD  . LYS E 5 20  ? 139.346 119.653 181.385 1.00 92.72  ? 26  LYS P CD  1 
ATOM   5890 C CE  . LYS E 5 20  ? 140.509 118.732 181.719 1.00 92.72  ? 26  LYS P CE  1 
ATOM   5891 N NZ  . LYS E 5 20  ? 140.629 117.611 180.748 1.00 92.72  ? 26  LYS P NZ  1 
ATOM   5892 N N   . GLU E 5 21  ? 141.429 124.755 181.988 1.00 94.82  ? 27  GLU P N   1 
ATOM   5893 C CA  . GLU E 5 21  ? 142.543 125.696 182.034 1.00 94.82  ? 27  GLU P CA  1 
ATOM   5894 C C   . GLU E 5 21  ? 142.266 126.823 183.019 1.00 94.82  ? 27  GLU P C   1 
ATOM   5895 O O   . GLU E 5 21  ? 143.161 127.252 183.755 1.00 94.82  ? 27  GLU P O   1 
ATOM   5896 C CB  . GLU E 5 21  ? 142.812 126.256 180.637 1.00 94.82  ? 27  GLU P CB  1 
ATOM   5897 C CG  . GLU E 5 21  ? 143.929 127.289 180.576 1.00 94.82  ? 27  GLU P CG  1 
ATOM   5898 C CD  . GLU E 5 21  ? 145.244 126.763 181.116 1.00 94.82  ? 27  GLU P CD  1 
ATOM   5899 O OE1 . GLU E 5 21  ? 145.355 126.583 182.346 1.00 94.82  ? 27  GLU P OE1 1 
ATOM   5900 O OE2 . GLU E 5 21  ? 146.168 126.530 180.308 1.00 94.82  ? 27  GLU P OE2 1 
ATOM   5901 N N   . PHE E 5 22  ? 141.029 127.323 183.041 1.00 99.96  ? 28  PHE P N   1 
ATOM   5902 C CA  . PHE E 5 22  ? 140.670 128.381 183.981 1.00 99.96  ? 28  PHE P CA  1 
ATOM   5903 C C   . PHE E 5 22  ? 140.797 127.901 185.422 1.00 99.96  ? 28  PHE P C   1 
ATOM   5904 O O   . PHE E 5 22  ? 141.323 128.619 186.282 1.00 99.96  ? 28  PHE P O   1 
ATOM   5905 C CB  . PHE E 5 22  ? 139.249 128.860 183.684 1.00 99.96  ? 28  PHE P CB  1 
ATOM   5906 C CG  . PHE E 5 22  ? 138.585 129.565 184.831 1.00 99.96  ? 28  PHE P CG  1 
ATOM   5907 C CD1 . PHE E 5 22  ? 138.829 130.905 185.072 1.00 99.96  ? 28  PHE P CD1 1 
ATOM   5908 C CD2 . PHE E 5 22  ? 137.697 128.891 185.653 1.00 99.96  ? 28  PHE P CD2 1 
ATOM   5909 C CE1 . PHE E 5 22  ? 138.210 131.557 186.119 1.00 99.96  ? 28  PHE P CE1 1 
ATOM   5910 C CE2 . PHE E 5 22  ? 137.076 129.540 186.701 1.00 99.96  ? 28  PHE P CE2 1 
ATOM   5911 C CZ  . PHE E 5 22  ? 137.331 130.874 186.932 1.00 99.96  ? 28  PHE P CZ  1 
ATOM   5912 N N   . ILE E 5 23  ? 140.330 126.684 185.703 1.00 100.64 ? 29  ILE P N   1 
ATOM   5913 C CA  . ILE E 5 23  ? 140.444 126.146 187.057 1.00 100.64 ? 29  ILE P CA  1 
ATOM   5914 C C   . ILE E 5 23  ? 141.909 125.962 187.433 1.00 100.64 ? 29  ILE P C   1 
ATOM   5915 O O   . ILE E 5 23  ? 142.314 126.242 188.567 1.00 100.64 ? 29  ILE P O   1 
ATOM   5916 C CB  . ILE E 5 23  ? 139.659 124.827 187.180 1.00 100.64 ? 29  ILE P CB  1 
ATOM   5917 C CG1 . ILE E 5 23  ? 138.155 125.076 187.020 1.00 100.64 ? 29  ILE P CG1 1 
ATOM   5918 C CG2 . ILE E 5 23  ? 139.952 124.159 188.515 1.00 100.64 ? 29  ILE P CG2 1 
ATOM   5919 C CD1 . ILE E 5 23  ? 137.543 125.957 188.097 1.00 100.64 ? 29  ILE P CD1 1 
ATOM   5920 N N   . ALA E 5 24  ? 142.725 125.481 186.491 1.00 97.30  ? 30  ALA P N   1 
ATOM   5921 C CA  . ALA E 5 24  ? 144.149 125.316 186.765 1.00 97.30  ? 30  ALA P CA  1 
ATOM   5922 C C   . ALA E 5 24  ? 144.808 126.655 187.063 1.00 97.30  ? 30  ALA P C   1 
ATOM   5923 O O   . ALA E 5 24  ? 145.628 126.764 187.982 1.00 97.30  ? 30  ALA P O   1 
ATOM   5924 C CB  . ALA E 5 24  ? 144.834 124.633 185.581 1.00 97.30  ? 30  ALA P CB  1 
ATOM   5925 N N   . TRP E 5 25  ? 144.462 127.690 186.294 1.00 100.01 ? 31  TRP P N   1 
ATOM   5926 C CA  . TRP E 5 25  ? 144.988 129.022 186.568 1.00 100.01 ? 31  TRP P CA  1 
ATOM   5927 C C   . TRP E 5 25  ? 144.573 129.495 187.953 1.00 100.01 ? 31  TRP P C   1 
ATOM   5928 O O   . TRP E 5 25  ? 145.374 130.089 188.682 1.00 100.01 ? 31  TRP P O   1 
ATOM   5929 C CB  . TRP E 5 25  ? 144.506 130.007 185.505 1.00 100.01 ? 31  TRP P CB  1 
ATOM   5930 C CG  . TRP E 5 25  ? 144.869 131.430 185.803 1.00 100.01 ? 31  TRP P CG  1 
ATOM   5931 C CD1 . TRP E 5 25  ? 146.125 131.960 185.860 1.00 100.01 ? 31  TRP P CD1 1 
ATOM   5932 C CD2 . TRP E 5 25  ? 143.967 132.503 186.096 1.00 100.01 ? 31  TRP P CD2 1 
ATOM   5933 N NE1 . TRP E 5 25  ? 146.060 133.298 186.165 1.00 100.01 ? 31  TRP P NE1 1 
ATOM   5934 C CE2 . TRP E 5 25  ? 144.745 133.656 186.316 1.00 100.01 ? 31  TRP P CE2 1 
ATOM   5935 C CE3 . TRP E 5 25  ? 142.575 132.602 186.193 1.00 100.01 ? 31  TRP P CE3 1 
ATOM   5936 C CZ2 . TRP E 5 25  ? 144.180 134.891 186.625 1.00 100.01 ? 31  TRP P CZ2 1 
ATOM   5937 C CZ3 . TRP E 5 25  ? 142.016 133.829 186.500 1.00 100.01 ? 31  TRP P CZ3 1 
ATOM   5938 C CH2 . TRP E 5 25  ? 142.817 134.957 186.713 1.00 100.01 ? 31  TRP P CH2 1 
ATOM   5939 N N   . LEU E 5 26  ? 143.319 129.240 188.332 1.00 102.68 ? 32  LEU P N   1 
ATOM   5940 C CA  . LEU E 5 26  ? 142.861 129.635 189.660 1.00 102.68 ? 32  LEU P CA  1 
ATOM   5941 C C   . LEU E 5 26  ? 143.652 128.923 190.748 1.00 102.68 ? 32  LEU P C   1 
ATOM   5942 O O   . LEU E 5 26  ? 144.048 129.539 191.744 1.00 102.68 ? 32  LEU P O   1 
ATOM   5943 C CB  . LEU E 5 26  ? 141.371 129.335 189.811 1.00 102.68 ? 32  LEU P CB  1 
ATOM   5944 C CG  . LEU E 5 26  ? 140.380 130.334 189.214 1.00 102.68 ? 32  LEU P CG  1 
ATOM   5945 C CD1 . LEU E 5 26  ? 138.969 129.928 189.594 1.00 102.68 ? 32  LEU P CD1 1 
ATOM   5946 C CD2 . LEU E 5 26  ? 140.666 131.763 189.657 1.00 102.68 ? 32  LEU P CD2 1 
ATOM   5947 N N   . VAL E 5 27  ? 143.891 127.621 190.576 1.00 96.83  ? 33  VAL P N   1 
ATOM   5948 C CA  . VAL E 5 27  ? 144.632 126.867 191.580 1.00 96.83  ? 33  VAL P CA  1 
ATOM   5949 C C   . VAL E 5 27  ? 146.053 127.402 191.710 1.00 96.83  ? 33  VAL P C   1 
ATOM   5950 O O   . VAL E 5 27  ? 146.562 127.587 192.822 1.00 96.83  ? 33  VAL P O   1 
ATOM   5951 C CB  . VAL E 5 27  ? 144.625 125.368 191.231 1.00 96.83  ? 33  VAL P CB  1 
ATOM   5952 N N   . LYS E 5 28  ? 146.711 127.660 190.585 1.00 78.85  ? 34  LYS P N   1 
ATOM   5953 C CA  . LYS E 5 28  ? 148.075 128.175 190.598 1.00 78.85  ? 34  LYS P CA  1 
ATOM   5954 C C   . LYS E 5 28  ? 148.101 129.620 191.083 1.00 78.85  ? 34  LYS P C   1 
ATOM   5955 O O   . LYS E 5 28  ? 148.954 130.407 190.671 0.00 78.85  ? 34  LYS P O   1 
ATOM   5956 C CB  . LYS E 5 28  ? 148.698 128.077 189.204 1.00 78.85  ? 34  LYS P CB  1 
ATOM   5957 N N   . VAL F 6 39  ? 130.024 121.811 181.243 1.00 96.45  ? 30  VAL R N   1 
ATOM   5958 C CA  . VAL F 6 39  ? 129.809 123.067 181.952 1.00 96.45  ? 30  VAL R CA  1 
ATOM   5959 C C   . VAL F 6 39  ? 130.446 124.190 181.149 1.00 96.45  ? 30  VAL R C   1 
ATOM   5960 O O   . VAL F 6 39  ? 131.614 124.093 180.749 1.00 96.45  ? 30  VAL R O   1 
ATOM   5961 C CB  . VAL F 6 39  ? 130.384 123.014 183.379 1.00 96.45  ? 30  VAL R CB  1 
ATOM   5962 C CG1 . VAL F 6 39  ? 129.773 121.857 184.155 1.00 96.45  ? 30  VAL R CG1 1 
ATOM   5963 C CG2 . VAL F 6 39  ? 131.903 122.896 183.345 1.00 96.45  ? 30  VAL R CG2 1 
ATOM   5964 N N   . SER F 6 40  ? 129.679 125.248 180.905 1.00 98.04  ? 31  SER R N   1 
ATOM   5965 C CA  . SER F 6 40  ? 130.201 126.401 180.188 1.00 98.04  ? 31  SER R CA  1 
ATOM   5966 C C   . SER F 6 40  ? 131.234 127.133 181.037 1.00 98.04  ? 31  SER R C   1 
ATOM   5967 O O   . SER F 6 40  ? 131.167 127.144 182.269 1.00 98.04  ? 31  SER R O   1 
ATOM   5968 C CB  . SER F 6 40  ? 129.068 127.352 179.808 1.00 98.04  ? 31  SER R CB  1 
ATOM   5969 N N   . LEU F 6 41  ? 132.203 127.754 180.360 1.00 97.82  ? 32  LEU R N   1 
ATOM   5970 C CA  . LEU F 6 41  ? 133.239 128.490 181.076 1.00 97.82  ? 32  LEU R CA  1 
ATOM   5971 C C   . LEU F 6 41  ? 132.637 129.626 181.890 1.00 97.82  ? 32  LEU R C   1 
ATOM   5972 O O   . LEU F 6 41  ? 133.036 129.856 183.038 1.00 97.82  ? 32  LEU R O   1 
ATOM   5973 C CB  . LEU F 6 41  ? 134.280 129.021 180.092 1.00 97.82  ? 32  LEU R CB  1 
ATOM   5974 C CG  . LEU F 6 41  ? 135.526 129.665 180.708 1.00 97.82  ? 32  LEU R CG  1 
ATOM   5975 C CD1 . LEU F 6 41  ? 136.699 129.541 179.759 1.00 97.82  ? 32  LEU R CD1 1 
ATOM   5976 C CD2 . LEU F 6 41  ? 135.289 131.131 181.047 1.00 97.82  ? 32  LEU R CD2 1 
ATOM   5977 N N   . TRP F 6 42  ? 131.678 130.354 181.314 1.00 101.84 ? 33  TRP R N   1 
ATOM   5978 C CA  . TRP F 6 42  ? 131.017 131.411 182.070 1.00 101.84 ? 33  TRP R CA  1 
ATOM   5979 C C   . TRP F 6 42  ? 130.258 130.833 183.259 1.00 101.84 ? 33  TRP R C   1 
ATOM   5980 O O   . TRP F 6 42  ? 130.210 131.446 184.330 1.00 101.84 ? 33  TRP R O   1 
ATOM   5981 C CB  . TRP F 6 42  ? 130.084 132.211 181.157 1.00 101.84 ? 33  TRP R CB  1 
ATOM   5982 C CG  . TRP F 6 42  ? 128.693 131.667 181.062 1.00 101.84 ? 33  TRP R CG  1 
ATOM   5983 C CD1 . TRP F 6 42  ? 128.256 130.671 180.238 1.00 101.84 ? 33  TRP R CD1 1 
ATOM   5984 C CD2 . TRP F 6 42  ? 127.550 132.097 181.812 1.00 101.84 ? 33  TRP R CD2 1 
ATOM   5985 N NE1 . TRP F 6 42  ? 126.914 130.451 180.431 1.00 101.84 ? 33  TRP R NE1 1 
ATOM   5986 C CE2 . TRP F 6 42  ? 126.456 131.314 181.392 1.00 101.84 ? 33  TRP R CE2 1 
ATOM   5987 C CE3 . TRP F 6 42  ? 127.344 133.066 182.799 1.00 101.84 ? 33  TRP R CE3 1 
ATOM   5988 C CZ2 . TRP F 6 42  ? 125.178 131.470 181.924 1.00 101.84 ? 33  TRP R CZ2 1 
ATOM   5989 C CZ3 . TRP F 6 42  ? 126.074 133.220 183.325 1.00 101.84 ? 33  TRP R CZ3 1 
ATOM   5990 C CH2 . TRP F 6 42  ? 125.008 132.425 182.888 1.00 101.84 ? 33  TRP R CH2 1 
ATOM   5991 N N   . GLU F 6 43  ? 129.670 129.646 183.092 1.00 103.65 ? 34  GLU R N   1 
ATOM   5992 C CA  . GLU F 6 43  ? 129.016 128.988 184.218 1.00 103.65 ? 34  GLU R CA  1 
ATOM   5993 C C   . GLU F 6 43  ? 130.017 128.656 185.317 1.00 103.65 ? 34  GLU R C   1 
ATOM   5994 O O   . GLU F 6 43  ? 129.736 128.855 186.505 1.00 103.65 ? 34  GLU R O   1 
ATOM   5995 C CB  . GLU F 6 43  ? 128.305 127.721 183.742 1.00 103.65 ? 34  GLU R CB  1 
ATOM   5996 N N   . THR F 6 44  ? 131.192 128.147 184.941 1.00 105.41 ? 35  THR R N   1 
ATOM   5997 C CA  . THR F 6 44  ? 132.217 127.844 185.935 1.00 105.41 ? 35  THR R CA  1 
ATOM   5998 C C   . THR F 6 44  ? 132.668 129.107 186.654 1.00 105.41 ? 35  THR R C   1 
ATOM   5999 O O   . THR F 6 44  ? 132.859 129.104 187.877 1.00 105.41 ? 35  THR R O   1 
ATOM   6000 C CB  . THR F 6 44  ? 133.410 127.157 185.269 1.00 105.41 ? 35  THR R CB  1 
ATOM   6001 N N   . VAL F 6 45  ? 132.847 130.199 185.908 1.00 108.16 ? 36  VAL R N   1 
ATOM   6002 C CA  . VAL F 6 45  ? 133.248 131.459 186.523 1.00 108.16 ? 36  VAL R CA  1 
ATOM   6003 C C   . VAL F 6 45  ? 132.180 131.935 187.498 1.00 108.16 ? 36  VAL R C   1 
ATOM   6004 O O   . VAL F 6 45  ? 132.489 132.397 188.601 1.00 108.16 ? 36  VAL R O   1 
ATOM   6005 C CB  . VAL F 6 45  ? 133.534 132.513 185.437 1.00 108.16 ? 36  VAL R CB  1 
ATOM   6006 C CG1 . VAL F 6 45  ? 133.499 133.918 186.025 1.00 108.16 ? 36  VAL R CG1 1 
ATOM   6007 C CG2 . VAL F 6 45  ? 134.876 132.238 184.774 1.00 108.16 ? 36  VAL R CG2 1 
ATOM   6008 N N   . GLN F 6 46  ? 130.909 131.839 187.105 1.00 113.60 ? 37  GLN R N   1 
ATOM   6009 C CA  . GLN F 6 46  ? 129.828 132.257 187.992 1.00 113.60 ? 37  GLN R CA  1 
ATOM   6010 C C   . GLN F 6 46  ? 129.803 131.415 189.261 1.00 113.60 ? 37  GLN R C   1 
ATOM   6011 O O   . GLN F 6 46  ? 129.627 131.946 190.364 1.00 113.60 ? 37  GLN R O   1 
ATOM   6012 C CB  . GLN F 6 46  ? 128.489 132.165 187.260 1.00 113.60 ? 37  GLN R CB  1 
ATOM   6013 N N   . LYS F 6 47  ? 129.979 130.099 189.125 1.00 112.70 ? 38  LYS R N   1 
ATOM   6014 C CA  . LYS F 6 47  ? 129.993 129.236 190.301 1.00 112.70 ? 38  LYS R CA  1 
ATOM   6015 C C   . LYS F 6 47  ? 131.158 129.581 191.223 1.00 112.70 ? 38  LYS R C   1 
ATOM   6016 O O   . LYS F 6 47  ? 130.999 129.620 192.450 1.00 112.70 ? 38  LYS R O   1 
ATOM   6017 C CB  . LYS F 6 47  ? 130.061 127.770 189.874 1.00 112.70 ? 38  LYS R CB  1 
ATOM   6018 C CG  . LYS F 6 47  ? 128.823 127.285 189.135 1.00 112.70 ? 38  LYS R CG  1 
ATOM   6019 C CD  . LYS F 6 47  ? 128.944 125.819 188.748 1.00 112.70 ? 38  LYS R CD  1 
ATOM   6020 C CE  . LYS F 6 47  ? 127.671 125.311 188.090 1.00 112.70 ? 38  LYS R CE  1 
ATOM   6021 N NZ  . LYS F 6 47  ? 127.430 125.953 186.769 1.00 112.70 ? 38  LYS R NZ  1 
ATOM   6022 N N   . TRP F 6 48  ? 132.340 129.829 190.652 1.00 113.80 ? 39  TRP R N   1 
ATOM   6023 C CA  . TRP F 6 48  ? 133.490 130.171 191.482 1.00 113.80 ? 39  TRP R CA  1 
ATOM   6024 C C   . TRP F 6 48  ? 133.295 131.515 192.172 1.00 113.80 ? 39  TRP R C   1 
ATOM   6025 O O   . TRP F 6 48  ? 133.681 131.681 193.333 1.00 113.80 ? 39  TRP R O   1 
ATOM   6026 C CB  . TRP F 6 48  ? 134.768 130.185 190.648 1.00 113.80 ? 39  TRP R CB  1 
ATOM   6027 C CG  . TRP F 6 48  ? 135.966 130.582 191.451 1.00 113.80 ? 39  TRP R CG  1 
ATOM   6028 C CD1 . TRP F 6 48  ? 136.497 129.913 192.513 1.00 113.80 ? 39  TRP R CD1 1 
ATOM   6029 C CD2 . TRP F 6 48  ? 136.781 131.745 191.263 1.00 113.80 ? 39  TRP R CD2 1 
ATOM   6030 N NE1 . TRP F 6 48  ? 137.593 130.583 192.997 1.00 113.80 ? 39  TRP R NE1 1 
ATOM   6031 C CE2 . TRP F 6 48  ? 137.789 131.711 192.247 1.00 113.80 ? 39  TRP R CE2 1 
ATOM   6032 C CE3 . TRP F 6 48  ? 136.759 132.808 190.356 1.00 113.80 ? 39  TRP R CE3 1 
ATOM   6033 C CZ2 . TRP F 6 48  ? 138.764 132.699 192.350 1.00 113.80 ? 39  TRP R CZ2 1 
ATOM   6034 C CZ3 . TRP F 6 48  ? 137.728 133.787 190.460 1.00 113.80 ? 39  TRP R CZ3 1 
ATOM   6035 C CH2 . TRP F 6 48  ? 138.716 133.727 191.450 1.00 113.80 ? 39  TRP R CH2 1 
ATOM   6036 N N   . ARG F 6 49  ? 132.715 132.492 191.472 1.00 117.96 ? 40  ARG R N   1 
ATOM   6037 C CA  . ARG F 6 49  ? 132.412 133.771 192.107 1.00 117.96 ? 40  ARG R CA  1 
ATOM   6038 C C   . ARG F 6 49  ? 131.413 133.597 193.242 1.00 117.96 ? 40  ARG R C   1 
ATOM   6039 O O   . ARG F 6 49  ? 131.546 134.227 194.297 1.00 117.96 ? 40  ARG R O   1 
ATOM   6040 C CB  . ARG F 6 49  ? 131.878 134.763 191.071 1.00 117.96 ? 40  ARG R CB  1 
ATOM   6041 N N   . GLU F 6 50  ? 130.399 132.752 193.043 1.00 124.12 ? 41  GLU R N   1 
ATOM   6042 C CA  . GLU F 6 50  ? 129.444 132.492 194.114 1.00 124.12 ? 41  GLU R CA  1 
ATOM   6043 C C   . GLU F 6 50  ? 130.133 131.860 195.317 1.00 124.12 ? 41  GLU R C   1 
ATOM   6044 O O   . GLU F 6 50  ? 129.873 132.242 196.465 1.00 124.12 ? 41  GLU R O   1 
ATOM   6045 C CB  . GLU F 6 50  ? 128.318 131.592 193.601 1.00 124.12 ? 41  GLU R CB  1 
ATOM   6046 N N   . TYR F 6 51  ? 131.018 130.891 195.074 1.00 122.02 ? 42  TYR R N   1 
ATOM   6047 C CA  . TYR F 6 51  ? 131.741 130.263 196.177 1.00 122.02 ? 42  TYR R CA  1 
ATOM   6048 C C   . TYR F 6 51  ? 132.631 131.270 196.894 1.00 122.02 ? 42  TYR R C   1 
ATOM   6049 O O   . TYR F 6 51  ? 132.727 131.257 198.126 1.00 122.02 ? 42  TYR R O   1 
ATOM   6050 C CB  . TYR F 6 51  ? 132.576 129.091 195.664 1.00 122.02 ? 42  TYR R CB  1 
ATOM   6051 N N   . ARG F 6 52  ? 133.304 132.138 196.137 1.00 122.83 ? 43  ARG R N   1 
ATOM   6052 C CA  . ARG F 6 52  ? 134.156 133.153 196.746 1.00 122.83 ? 43  ARG R CA  1 
ATOM   6053 C C   . ARG F 6 52  ? 133.336 134.113 197.597 1.00 122.83 ? 43  ARG R C   1 
ATOM   6054 O O   . ARG F 6 52  ? 133.754 134.493 198.696 1.00 122.83 ? 43  ARG R O   1 
ATOM   6055 C CB  . ARG F 6 52  ? 134.918 133.910 195.658 1.00 122.83 ? 43  ARG R CB  1 
ATOM   6056 C CG  . ARG F 6 52  ? 135.857 135.002 196.176 1.00 122.83 ? 43  ARG R CG  1 
ATOM   6057 C CD  . ARG F 6 52  ? 135.172 136.359 196.344 1.00 122.83 ? 43  ARG R CD  1 
ATOM   6058 N NE  . ARG F 6 52  ? 134.289 136.695 195.233 1.00 122.83 ? 43  ARG R NE  1 
ATOM   6059 C CZ  . ARG F 6 52  ? 133.338 137.618 195.282 1.00 122.83 ? 43  ARG R CZ  1 
ATOM   6060 N NH1 . ARG F 6 52  ? 133.115 138.326 196.378 1.00 122.83 ? 43  ARG R NH1 1 
ATOM   6061 N NH2 . ARG F 6 52  ? 132.591 137.837 194.203 1.00 122.83 ? 43  ARG R NH2 1 
ATOM   6062 N N   . ARG F 6 53  ? 132.170 134.526 197.099 1.00 123.39 ? 44  ARG R N   1 
ATOM   6063 C CA  . ARG F 6 53  ? 131.302 135.401 197.880 1.00 123.39 ? 44  ARG R CA  1 
ATOM   6064 C C   . ARG F 6 53  ? 130.839 134.708 199.154 1.00 123.39 ? 44  ARG R C   1 
ATOM   6065 O O   . ARG F 6 53  ? 130.810 135.319 200.228 1.00 123.39 ? 44  ARG R O   1 
ATOM   6066 C CB  . ARG F 6 53  ? 130.104 135.835 197.035 1.00 123.39 ? 44  ARG R CB  1 
ATOM   6067 N N   . GLN F 6 54  ? 130.474 133.428 199.054 1.00 122.73 ? 45  GLN R N   1 
ATOM   6068 C CA  . GLN F 6 54  ? 130.067 132.682 200.241 1.00 122.73 ? 45  GLN R CA  1 
ATOM   6069 C C   . GLN F 6 54  ? 131.201 132.606 201.255 1.00 122.73 ? 45  GLN R C   1 
ATOM   6070 O O   . GLN F 6 54  ? 130.984 132.797 202.457 1.00 122.73 ? 45  GLN R O   1 
ATOM   6071 C CB  . GLN F 6 54  ? 129.612 131.277 199.846 1.00 122.73 ? 45  GLN R CB  1 
ATOM   6072 N N   . CYS F 6 55  ? 132.420 132.328 200.788 1.00 124.62 ? 46  CYS R N   1 
ATOM   6073 C CA  . CYS F 6 55  ? 133.561 132.239 201.694 1.00 124.62 ? 46  CYS R CA  1 
ATOM   6074 C C   . CYS F 6 55  ? 133.848 133.583 202.351 1.00 124.62 ? 46  CYS R C   1 
ATOM   6075 O O   . CYS F 6 55  ? 134.132 133.647 203.553 1.00 124.62 ? 46  CYS R O   1 
ATOM   6076 C CB  . CYS F 6 55  ? 134.791 131.739 200.938 1.00 124.62 ? 46  CYS R CB  1 
ATOM   6077 S SG  . CYS F 6 55  ? 136.350 131.953 201.827 1.00 124.62 ? 46  CYS R SG  1 
ATOM   6078 N N   . GLN F 6 56  ? 133.787 134.669 201.577 1.00 121.40 ? 47  GLN R N   1 
ATOM   6079 C CA  . GLN F 6 56  ? 134.021 135.993 202.142 1.00 121.40 ? 47  GLN R CA  1 
ATOM   6080 C C   . GLN F 6 56  ? 132.966 136.336 203.185 1.00 121.40 ? 47  GLN R C   1 
ATOM   6081 O O   . GLN F 6 56  ? 133.280 136.906 204.236 1.00 121.40 ? 47  GLN R O   1 
ATOM   6082 C CB  . GLN F 6 56  ? 134.036 137.041 201.029 1.00 121.40 ? 47  GLN R CB  1 
ATOM   6083 N N   . ARG F 6 57  ? 131.705 135.999 202.908 1.00 116.50 ? 48  ARG R N   1 
ATOM   6084 C CA  . ARG F 6 57  ? 130.642 136.250 203.874 1.00 116.50 ? 48  ARG R CA  1 
ATOM   6085 C C   . ARG F 6 57  ? 130.839 135.421 205.139 1.00 116.50 ? 48  ARG R C   1 
ATOM   6086 O O   . ARG F 6 57  ? 130.612 135.910 206.252 1.00 116.50 ? 48  ARG R O   1 
ATOM   6087 C CB  . ARG F 6 57  ? 129.288 135.949 203.235 1.00 116.50 ? 48  ARG R CB  1 
ATOM   6088 N N   . SER F 6 58  ? 131.262 134.165 204.986 1.00 117.86 ? 49  SER R N   1 
ATOM   6089 C CA  . SER F 6 58  ? 131.365 133.275 206.139 1.00 117.86 ? 49  SER R CA  1 
ATOM   6090 C C   . SER F 6 58  ? 132.561 133.626 207.016 1.00 117.86 ? 49  SER R C   1 
ATOM   6091 O O   . SER F 6 58  ? 132.448 133.641 208.247 1.00 117.86 ? 49  SER R O   1 
ATOM   6092 C CB  . SER F 6 58  ? 131.455 131.824 205.669 1.00 117.86 ? 49  SER R CB  1 
ATOM   6093 N N   . LEU F 6 59  ? 133.717 133.910 206.408 1.00 117.98 ? 50  LEU R N   1 
ATOM   6094 C CA  . LEU F 6 59  ? 134.913 134.165 207.204 1.00 117.98 ? 50  LEU R CA  1 
ATOM   6095 C C   . LEU F 6 59  ? 134.730 135.370 208.116 1.00 117.98 ? 50  LEU R C   1 
ATOM   6096 O O   . LEU F 6 59  ? 135.330 135.427 209.195 1.00 117.98 ? 50  LEU R O   1 
ATOM   6097 C CB  . LEU F 6 59  ? 136.129 134.361 206.293 1.00 117.98 ? 50  LEU R CB  1 
ATOM   6098 N N   . THR F 6 60  ? 133.908 136.338 207.706 1.00 117.26 ? 51  THR R N   1 
ATOM   6099 C CA  . THR F 6 60  ? 133.582 137.446 208.597 1.00 117.26 ? 51  THR R CA  1 
ATOM   6100 C C   . THR F 6 60  ? 132.692 136.988 209.744 1.00 117.26 ? 51  THR R C   1 
ATOM   6101 O O   . THR F 6 60  ? 132.749 137.559 210.838 1.00 117.26 ? 51  THR R O   1 
ATOM   6102 C CB  . THR F 6 60  ? 132.900 138.571 207.818 1.00 117.26 ? 51  THR R CB  1 
ATOM   6103 N N   . GLU F 6 61  ? 131.870 135.964 209.514 1.00 116.08 ? 52  GLU R N   1 
ATOM   6104 C CA  . GLU F 6 61  ? 131.009 135.415 210.552 1.00 116.08 ? 52  GLU R CA  1 
ATOM   6105 C C   . GLU F 6 61  ? 131.630 134.225 211.271 1.00 116.08 ? 52  GLU R C   1 
ATOM   6106 O O   . GLU F 6 61  ? 131.163 133.865 212.358 1.00 116.08 ? 52  GLU R O   1 
ATOM   6107 C CB  . GLU F 6 61  ? 129.664 134.989 209.954 1.00 116.08 ? 52  GLU R CB  1 
ATOM   6108 N N   . ASP F 6 62  ? 132.659 133.612 210.700 1.00 115.83 ? 53  ASP R N   1 
ATOM   6109 C CA  . ASP F 6 62  ? 133.292 132.468 211.345 1.00 115.83 ? 53  ASP R CA  1 
ATOM   6110 C C   . ASP F 6 62  ? 134.002 132.923 212.616 1.00 115.83 ? 53  ASP R C   1 
ATOM   6111 O O   . ASP F 6 62  ? 134.843 133.830 212.558 1.00 115.83 ? 53  ASP R O   1 
ATOM   6112 C CB  . ASP F 6 62  ? 134.285 131.800 210.397 1.00 115.83 ? 53  ASP R CB  1 
ATOM   6113 N N   . PRO F 6 63  ? 133.705 132.333 213.771 1.00 113.87 ? 54  PRO R N   1 
ATOM   6114 C CA  . PRO F 6 63  ? 134.355 132.765 215.009 1.00 113.87 ? 54  PRO R CA  1 
ATOM   6115 C C   . PRO F 6 63  ? 135.769 132.221 215.102 1.00 113.87 ? 54  PRO R C   1 
ATOM   6116 O O   . PRO F 6 63  ? 136.141 131.306 214.352 1.00 113.87 ? 54  PRO R O   1 
ATOM   6117 C CB  . PRO F 6 63  ? 133.455 132.174 216.104 1.00 113.87 ? 54  PRO R CB  1 
ATOM   6118 C CG  . PRO F 6 63  ? 132.877 130.955 215.484 1.00 113.87 ? 54  PRO R CG  1 
ATOM   6119 C CD  . PRO F 6 63  ? 132.752 131.232 214.007 1.00 113.87 ? 54  PRO R CD  1 
ATOM   6120 N N   . PRO F 6 64  ? 136.588 132.756 216.006 1.00 109.13 ? 55  PRO R N   1 
ATOM   6121 C CA  . PRO F 6 64  ? 137.929 132.209 216.177 1.00 109.13 ? 55  PRO R CA  1 
ATOM   6122 C C   . PRO F 6 64  ? 137.861 130.784 216.686 1.00 109.13 ? 55  PRO R C   1 
ATOM   6123 O O   . PRO F 6 64  ? 136.885 130.388 217.350 1.00 109.13 ? 55  PRO R O   1 
ATOM   6124 C CB  . PRO F 6 64  ? 138.567 133.149 217.210 1.00 109.13 ? 55  PRO R CB  1 
ATOM   6125 C CG  . PRO F 6 64  ? 137.731 134.381 217.200 1.00 109.13 ? 55  PRO R CG  1 
ATOM   6126 C CD  . PRO F 6 64  ? 136.352 133.928 216.864 1.00 109.13 ? 55  PRO R CD  1 
ATOM   6127 N N   . PRO F 6 65  ? 138.882 129.969 216.401 1.00 107.35 ? 56  PRO R N   1 
ATOM   6128 C CA  . PRO F 6 65  ? 138.845 128.566 216.831 1.00 107.35 ? 56  PRO R CA  1 
ATOM   6129 C C   . PRO F 6 65  ? 139.107 128.392 218.320 1.00 107.35 ? 56  PRO R C   1 
ATOM   6130 O O   . PRO F 6 65  ? 139.199 127.261 218.808 1.00 107.35 ? 56  PRO R O   1 
ATOM   6131 C CB  . PRO F 6 65  ? 139.950 127.919 215.989 1.00 107.35 ? 56  PRO R CB  1 
ATOM   6132 C CG  . PRO F 6 65  ? 140.934 129.016 215.778 1.00 107.35 ? 56  PRO R CG  1 
ATOM   6133 C CD  . PRO F 6 65  ? 140.138 130.298 215.704 1.00 107.35 ? 56  PRO R CD  1 
ATOM   6134 N N   . ALA F 6 66  ? 139.230 129.501 219.050 1.00 103.02 ? 57  ALA R N   1 
ATOM   6135 C CA  . ALA F 6 66  ? 139.496 129.464 220.487 1.00 103.02 ? 57  ALA R CA  1 
ATOM   6136 C C   . ALA F 6 66  ? 140.797 128.723 220.784 1.00 103.02 ? 57  ALA R C   1 
ATOM   6137 O O   . ALA F 6 66  ? 140.907 127.991 221.769 1.00 103.02 ? 57  ALA R O   1 
ATOM   6138 C CB  . ALA F 6 66  ? 138.327 128.834 221.246 1.00 103.02 ? 57  ALA R CB  1 
ATOM   6139 N N   . THR F 6 67  ? 141.792 128.915 219.920 1.00 101.69 ? 58  THR R N   1 
ATOM   6140 C CA  . THR F 6 67  ? 143.102 128.296 220.072 1.00 101.69 ? 58  THR R CA  1 
ATOM   6141 C C   . THR F 6 67  ? 144.172 129.367 219.933 1.00 101.69 ? 58  THR R C   1 
ATOM   6142 O O   . THR F 6 67  ? 144.102 130.205 219.029 1.00 101.69 ? 58  THR R O   1 
ATOM   6143 C CB  . THR F 6 67  ? 143.322 127.192 219.032 1.00 101.69 ? 58  THR R CB  1 
ATOM   6144 N N   . ASP F 6 68  ? 145.156 129.338 220.828 1.00 96.60  ? 59  ASP R N   1 
ATOM   6145 C CA  . ASP F 6 68  ? 146.230 130.320 220.788 1.00 96.60  ? 59  ASP R CA  1 
ATOM   6146 C C   . ASP F 6 68  ? 147.105 130.104 219.559 1.00 96.60  ? 59  ASP R C   1 
ATOM   6147 O O   . ASP F 6 68  ? 147.372 128.968 219.159 1.00 96.60  ? 59  ASP R O   1 
ATOM   6148 C CB  . ASP F 6 68  ? 147.076 130.231 222.057 1.00 96.60  ? 59  ASP R CB  1 
ATOM   6149 N N   . LEU F 6 69  ? 147.552 131.208 218.962 1.00 100.18 ? 60  LEU R N   1 
ATOM   6150 C CA  . LEU F 6 69  ? 148.416 131.163 217.782 1.00 100.18 ? 60  LEU R CA  1 
ATOM   6151 C C   . LEU F 6 69  ? 147.775 130.343 216.664 1.00 100.18 ? 60  LEU R C   1 
ATOM   6152 O O   . LEU F 6 69  ? 148.445 129.582 215.964 1.00 100.18 ? 60  LEU R O   1 
ATOM   6153 C CB  . LEU F 6 69  ? 149.798 130.609 218.135 1.00 100.18 ? 60  LEU R CB  1 
ATOM   6154 N N   . PHE F 6 70  ? 146.465 130.499 216.496 1.00 106.17 ? 61  PHE R N   1 
ATOM   6155 C CA  . PHE F 6 70  ? 145.747 129.787 215.450 1.00 106.17 ? 61  PHE R CA  1 
ATOM   6156 C C   . PHE F 6 70  ? 145.973 130.456 214.102 1.00 106.17 ? 61  PHE R C   1 
ATOM   6157 O O   . PHE F 6 70  ? 145.995 131.686 213.997 1.00 106.17 ? 61  PHE R O   1 
ATOM   6158 C CB  . PHE F 6 70  ? 144.251 129.739 215.764 1.00 106.17 ? 61  PHE R CB  1 
ATOM   6159 N N   . CYS F 6 71  ? 146.147 129.638 213.067 1.00 113.41 ? 62  CYS R N   1 
ATOM   6160 C CA  . CYS F 6 71  ? 146.310 130.168 211.721 1.00 113.41 ? 62  CYS R CA  1 
ATOM   6161 C C   . CYS F 6 71  ? 145.053 130.915 211.297 1.00 113.41 ? 62  CYS R C   1 
ATOM   6162 O O   . CYS F 6 71  ? 143.934 130.422 211.470 1.00 113.41 ? 62  CYS R O   1 
ATOM   6163 C CB  . CYS F 6 71  ? 146.615 129.036 210.742 1.00 113.41 ? 62  CYS R CB  1 
ATOM   6164 S SG  . CYS F 6 71  ? 148.357 128.555 210.677 1.00 113.41 ? 62  CYS R SG  1 
ATOM   6165 N N   . ASN F 6 72  ? 145.239 132.108 210.739 1.00 114.79 ? 63  ASN R N   1 
ATOM   6166 C CA  . ASN F 6 72  ? 144.107 132.916 210.308 1.00 114.79 ? 63  ASN R CA  1 
ATOM   6167 C C   . ASN F 6 72  ? 143.462 132.302 209.073 1.00 114.79 ? 63  ASN R C   1 
ATOM   6168 O O   . ASN F 6 72  ? 144.152 131.908 208.128 1.00 114.79 ? 63  ASN R O   1 
ATOM   6169 C CB  . ASN F 6 72  ? 144.559 134.345 210.013 1.00 114.79 ? 63  ASN R CB  1 
ATOM   6170 C CG  . ASN F 6 72  ? 145.222 135.005 211.205 1.00 114.79 ? 63  ASN R CG  1 
ATOM   6171 O OD1 . ASN F 6 72  ? 146.410 134.807 211.458 1.00 114.79 ? 63  ASN R OD1 1 
ATOM   6172 N ND2 . ASN F 6 72  ? 144.454 135.795 211.946 1.00 114.79 ? 63  ASN R ND2 1 
ATOM   6173 N N   . ARG F 6 73  ? 142.134 132.218 209.082 1.00 113.85 ? 64  ARG R N   1 
ATOM   6174 C CA  . ARG F 6 73  ? 141.412 131.707 207.925 1.00 113.85 ? 64  ARG R CA  1 
ATOM   6175 C C   . ARG F 6 73  ? 141.675 132.593 206.714 1.00 113.85 ? 64  ARG R C   1 
ATOM   6176 O O   . ARG F 6 73  ? 141.601 133.822 206.802 1.00 113.85 ? 64  ARG R O   1 
ATOM   6177 C CB  . ARG F 6 73  ? 139.913 131.635 208.222 1.00 113.85 ? 64  ARG R CB  1 
ATOM   6178 N N   . THR F 6 74  ? 141.981 131.964 205.581 1.00 119.17 ? 65  THR R N   1 
ATOM   6179 C CA  . THR F 6 74  ? 142.374 132.686 204.379 1.00 119.17 ? 65  THR R CA  1 
ATOM   6180 C C   . THR F 6 74  ? 141.768 132.013 203.156 1.00 119.17 ? 65  THR R C   1 
ATOM   6181 O O   . THR F 6 74  ? 141.418 130.830 203.179 1.00 119.17 ? 65  THR R O   1 
ATOM   6182 C CB  . THR F 6 74  ? 143.901 132.751 204.235 1.00 119.17 ? 65  THR R CB  1 
ATOM   6183 N N   . PHE F 6 75  ? 141.645 132.791 202.084 1.00 119.15 ? 66  PHE R N   1 
ATOM   6184 C CA  . PHE F 6 75  ? 141.154 132.311 200.799 1.00 119.15 ? 66  PHE R CA  1 
ATOM   6185 C C   . PHE F 6 75  ? 142.267 132.445 199.771 1.00 119.15 ? 66  PHE R C   1 
ATOM   6186 O O   . PHE F 6 75  ? 142.820 133.535 199.588 1.00 119.15 ? 66  PHE R O   1 
ATOM   6187 C CB  . PHE F 6 75  ? 139.915 133.094 200.359 1.00 119.15 ? 66  PHE R CB  1 
ATOM   6188 N N   . ASP F 6 76  ? 142.592 131.338 199.103 1.00 118.56 ? 67  ASP R N   1 
ATOM   6189 C CA  . ASP F 6 76  ? 143.694 131.280 198.150 1.00 118.56 ? 67  ASP R CA  1 
ATOM   6190 C C   . ASP F 6 76  ? 143.220 131.066 196.713 1.00 118.56 ? 67  ASP R C   1 
ATOM   6191 O O   . ASP F 6 76  ? 143.926 130.460 195.903 1.00 118.56 ? 67  ASP R O   1 
ATOM   6192 C CB  . ASP F 6 76  ? 144.696 130.204 198.584 1.00 118.56 ? 67  ASP R CB  1 
ATOM   6193 N N   . GLU F 6 77  ? 142.034 131.576 196.382 1.00 115.47 ? 68  GLU R N   1 
ATOM   6194 C CA  . GLU F 6 77  ? 141.444 131.516 195.047 1.00 115.47 ? 68  GLU R CA  1 
ATOM   6195 C C   . GLU F 6 77  ? 141.094 130.099 194.613 1.00 115.47 ? 68  GLU R C   1 
ATOM   6196 O O   . GLU F 6 77  ? 140.733 129.890 193.447 1.00 115.47 ? 68  GLU R O   1 
ATOM   6197 C CB  . GLU F 6 77  ? 142.361 132.150 193.993 1.00 115.47 ? 68  GLU R CB  1 
ATOM   6198 N N   . TYR F 6 78  ? 141.188 129.122 195.505 1.00 115.68 ? 69  TYR R N   1 
ATOM   6199 C CA  . TYR F 6 78  ? 140.810 127.747 195.197 1.00 115.68 ? 69  TYR R CA  1 
ATOM   6200 C C   . TYR F 6 78  ? 139.825 127.170 196.200 1.00 115.68 ? 69  TYR R C   1 
ATOM   6201 O O   . TYR F 6 78  ? 138.946 126.396 195.814 1.00 115.68 ? 69  TYR R O   1 
ATOM   6202 C CB  . TYR F 6 78  ? 142.061 126.857 195.132 1.00 115.68 ? 69  TYR R CB  1 
ATOM   6203 C CG  . TYR F 6 78  ? 141.752 125.389 194.947 1.00 115.68 ? 69  TYR R CG  1 
ATOM   6204 C CD1 . TYR F 6 78  ? 141.116 124.932 193.801 1.00 115.68 ? 69  TYR R CD1 1 
ATOM   6205 C CD2 . TYR F 6 78  ? 142.094 124.460 195.921 1.00 115.68 ? 69  TYR R CD2 1 
ATOM   6206 C CE1 . TYR F 6 78  ? 140.832 123.591 193.629 1.00 115.68 ? 69  TYR R CE1 1 
ATOM   6207 C CE2 . TYR F 6 78  ? 141.814 123.118 195.757 1.00 115.68 ? 69  TYR R CE2 1 
ATOM   6208 C CZ  . TYR F 6 78  ? 141.183 122.689 194.610 1.00 115.68 ? 69  TYR R CZ  1 
ATOM   6209 O OH  . TYR F 6 78  ? 140.901 121.352 194.443 1.00 115.68 ? 69  TYR R OH  1 
ATOM   6210 N N   . ALA F 6 79  ? 139.949 127.523 197.477 1.00 120.15 ? 70  ALA R N   1 
ATOM   6211 C CA  . ALA F 6 79  ? 139.043 127.022 198.499 1.00 120.15 ? 70  ALA R CA  1 
ATOM   6212 C C   . ALA F 6 79  ? 139.113 127.940 199.709 1.00 120.15 ? 70  ALA R C   1 
ATOM   6213 O O   . ALA F 6 79  ? 140.039 128.743 199.850 1.00 120.15 ? 70  ALA R O   1 
ATOM   6214 C CB  . ALA F 6 79  ? 139.382 125.581 198.893 1.00 120.15 ? 70  ALA R CB  1 
ATOM   6215 N N   . CYS F 6 80  ? 138.119 127.806 200.583 1.00 125.05 ? 71  CYS R N   1 
ATOM   6216 C CA  . CYS F 6 80  ? 138.043 128.595 201.805 1.00 125.05 ? 71  CYS R CA  1 
ATOM   6217 C C   . CYS F 6 80  ? 138.675 127.806 202.944 1.00 125.05 ? 71  CYS R C   1 
ATOM   6218 O O   . CYS F 6 80  ? 138.237 126.692 203.251 1.00 125.05 ? 71  CYS R O   1 
ATOM   6219 C CB  . CYS F 6 80  ? 136.591 128.945 202.130 1.00 125.05 ? 71  CYS R CB  1 
ATOM   6220 S SG  . CYS F 6 80  ? 136.388 130.418 203.158 1.00 125.05 ? 71  CYS R SG  1 
ATOM   6221 N N   . TRP F 6 81  ? 139.703 128.383 203.569 1.00 121.28 ? 72  TRP R N   1 
ATOM   6222 C CA  . TRP F 6 81  ? 140.413 127.718 204.649 1.00 121.28 ? 72  TRP R CA  1 
ATOM   6223 C C   . TRP F 6 81  ? 139.955 128.285 205.982 1.00 121.28 ? 72  TRP R C   1 
ATOM   6224 O O   . TRP F 6 81  ? 140.254 129.451 206.279 1.00 121.28 ? 72  TRP R O   1 
ATOM   6225 C CB  . TRP F 6 81  ? 141.921 127.895 204.490 1.00 121.28 ? 72  TRP R CB  1 
ATOM   6226 C CG  . TRP F 6 81  ? 142.518 127.034 203.427 1.00 121.28 ? 72  TRP R CG  1 
ATOM   6227 C CD1 . TRP F 6 81  ? 142.855 127.409 202.159 1.00 121.28 ? 72  TRP R CD1 1 
ATOM   6228 C CD2 . TRP F 6 81  ? 142.852 125.646 203.537 1.00 121.28 ? 72  TRP R CD2 1 
ATOM   6229 N NE1 . TRP F 6 81  ? 143.378 126.340 201.473 1.00 121.28 ? 72  TRP R NE1 1 
ATOM   6230 C CE2 . TRP F 6 81  ? 143.386 125.245 202.297 1.00 121.28 ? 72  TRP R CE2 1 
ATOM   6231 C CE3 . TRP F 6 81  ? 142.751 124.703 204.564 1.00 121.28 ? 72  TRP R CE3 1 
ATOM   6232 C CZ2 . TRP F 6 81  ? 143.818 123.943 202.057 1.00 121.28 ? 72  TRP R CZ2 1 
ATOM   6233 C CZ3 . TRP F 6 81  ? 143.179 123.412 204.323 1.00 121.28 ? 72  TRP R CZ3 1 
ATOM   6234 C CH2 . TRP F 6 81  ? 143.705 123.043 203.080 1.00 121.28 ? 72  TRP R CH2 1 
ATOM   6235 N N   . PRO F 6 82  ? 139.239 127.524 206.816 1.00 117.43 ? 73  PRO R N   1 
ATOM   6236 C CA  . PRO F 6 82  ? 138.931 128.014 208.166 1.00 117.43 ? 73  PRO R CA  1 
ATOM   6237 C C   . PRO F 6 82  ? 140.191 128.178 208.998 1.00 117.43 ? 73  PRO R C   1 
ATOM   6238 O O   . PRO F 6 82  ? 141.288 127.839 208.541 1.00 117.43 ? 73  PRO R O   1 
ATOM   6239 C CB  . PRO F 6 82  ? 138.008 126.929 208.741 1.00 117.43 ? 73  PRO R CB  1 
ATOM   6240 C CG  . PRO F 6 82  ? 137.500 126.174 207.559 1.00 117.43 ? 73  PRO R CG  1 
ATOM   6241 C CD  . PRO F 6 82  ? 138.588 126.232 206.538 1.00 117.43 ? 73  PRO R CD  1 
ATOM   6242 N N   . ASP F 6 83  ? 140.054 128.697 210.214 1.00 108.46 ? 74  ASP R N   1 
ATOM   6243 C CA  . ASP F 6 83  ? 141.214 128.888 211.073 1.00 108.46 ? 74  ASP R CA  1 
ATOM   6244 C C   . ASP F 6 83  ? 141.895 127.552 211.339 1.00 108.46 ? 74  ASP R C   1 
ATOM   6245 O O   . ASP F 6 83  ? 141.241 126.560 211.674 1.00 108.46 ? 74  ASP R O   1 
ATOM   6246 C CB  . ASP F 6 83  ? 140.795 129.541 212.388 1.00 108.46 ? 74  ASP R CB  1 
ATOM   6247 N N   . GLY F 6 84  ? 143.218 127.529 211.188 1.00 108.01 ? 75  GLY R N   1 
ATOM   6248 C CA  . GLY F 6 84  ? 143.995 126.314 211.357 1.00 108.01 ? 75  GLY R CA  1 
ATOM   6249 C C   . GLY F 6 84  ? 144.590 126.239 212.751 1.00 108.01 ? 75  GLY R C   1 
ATOM   6250 O O   . GLY F 6 84  ? 145.199 127.198 213.233 1.00 108.01 ? 75  GLY R O   1 
ATOM   6251 N N   . GLU F 6 85  ? 144.407 125.087 213.390 1.00 101.48 ? 76  GLU R N   1 
ATOM   6252 C CA  . GLU F 6 85  ? 144.946 124.888 214.723 1.00 101.48 ? 76  GLU R CA  1 
ATOM   6253 C C   . GLU F 6 85  ? 146.474 124.864 214.675 1.00 101.48 ? 76  GLU R C   1 
ATOM   6254 O O   . GLU F 6 85  ? 147.065 124.394 213.699 1.00 101.48 ? 76  GLU R O   1 
ATOM   6255 C CB  . GLU F 6 85  ? 144.424 123.586 215.323 1.00 101.48 ? 76  GLU R CB  1 
ATOM   6256 N N   . PRO F 6 86  ? 147.137 125.366 215.715 1.00 104.00 ? 77  PRO R N   1 
ATOM   6257 C CA  . PRO F 6 86  ? 148.604 125.387 215.704 1.00 104.00 ? 77  PRO R CA  1 
ATOM   6258 C C   . PRO F 6 86  ? 149.184 123.981 215.648 1.00 104.00 ? 77  PRO R C   1 
ATOM   6259 O O   . PRO F 6 86  ? 148.680 123.054 216.286 1.00 104.00 ? 77  PRO R O   1 
ATOM   6260 C CB  . PRO F 6 86  ? 148.960 126.096 217.015 1.00 104.00 ? 77  PRO R CB  1 
ATOM   6261 C CG  . PRO F 6 86  ? 147.780 125.884 217.895 1.00 104.00 ? 77  PRO R CG  1 
ATOM   6262 C CD  . PRO F 6 86  ? 146.589 125.869 216.986 1.00 104.00 ? 77  PRO R CD  1 
ATOM   6263 N N   . GLY F 6 87  ? 150.257 123.833 214.878 1.00 100.14 ? 78  GLY R N   1 
ATOM   6264 C CA  . GLY F 6 87  ? 150.965 122.564 214.810 1.00 100.14 ? 78  GLY R CA  1 
ATOM   6265 C C   . GLY F 6 87  ? 150.098 121.402 214.380 1.00 100.14 ? 78  GLY R C   1 
ATOM   6266 O O   . GLY F 6 87  ? 150.218 120.303 214.936 1.00 100.14 ? 78  GLY R O   1 
ATOM   6267 N N   . SER F 6 88  ? 149.223 121.618 213.401 1.00 106.02 ? 79  SER R N   1 
ATOM   6268 C CA  . SER F 6 88  ? 148.342 120.563 212.926 1.00 106.02 ? 79  SER R CA  1 
ATOM   6269 C C   . SER F 6 88  ? 147.922 120.867 211.496 1.00 106.02 ? 79  SER R C   1 
ATOM   6270 O O   . SER F 6 88  ? 147.994 122.009 211.034 1.00 106.02 ? 79  SER R O   1 
ATOM   6271 C CB  . SER F 6 88  ? 147.107 120.415 213.824 1.00 106.02 ? 79  SER R CB  1 
ATOM   6272 N N   . PHE F 6 89  ? 147.484 119.823 210.800 1.00 113.27 ? 80  PHE R N   1 
ATOM   6273 C CA  . PHE F 6 89  ? 146.990 119.970 209.440 1.00 113.27 ? 80  PHE R CA  1 
ATOM   6274 C C   . PHE F 6 89  ? 145.519 120.366 209.452 1.00 113.27 ? 80  PHE R C   1 
ATOM   6275 O O   . PHE F 6 89  ? 144.761 120.000 210.356 1.00 113.27 ? 80  PHE R O   1 
ATOM   6276 C CB  . PHE F 6 89  ? 147.170 118.668 208.657 1.00 113.27 ? 80  PHE R CB  1 
ATOM   6277 N N   . VAL F 6 90  ? 145.120 121.121 208.433 1.00 118.22 ? 81  VAL R N   1 
ATOM   6278 C CA  . VAL F 6 90  ? 143.750 121.596 208.282 1.00 118.22 ? 81  VAL R CA  1 
ATOM   6279 C C   . VAL F 6 90  ? 143.111 120.844 207.123 1.00 118.22 ? 81  VAL R C   1 
ATOM   6280 O O   . VAL F 6 90  ? 143.668 120.801 206.020 1.00 118.22 ? 81  VAL R O   1 
ATOM   6281 C CB  . VAL F 6 90  ? 143.701 123.116 208.045 1.00 118.22 ? 81  VAL R CB  1 
ATOM   6282 N N   . ASN F 6 91  ? 141.949 120.250 207.377 1.00 120.13 ? 82  ASN R N   1 
ATOM   6283 C CA  . ASN F 6 91  ? 141.219 119.477 206.383 1.00 120.13 ? 82  ASN R CA  1 
ATOM   6284 C C   . ASN F 6 91  ? 139.981 120.252 205.956 1.00 120.13 ? 82  ASN R C   1 
ATOM   6285 O O   . ASN F 6 91  ? 139.181 120.667 206.801 1.00 120.13 ? 82  ASN R O   1 
ATOM   6286 C CB  . ASN F 6 91  ? 140.822 118.108 206.940 1.00 120.13 ? 82  ASN R CB  1 
ATOM   6287 N N   . VAL F 6 92  ? 139.829 120.446 204.649 1.00 121.32 ? 83  VAL R N   1 
ATOM   6288 C CA  . VAL F 6 92  ? 138.702 121.174 204.080 1.00 121.32 ? 83  VAL R CA  1 
ATOM   6289 C C   . VAL F 6 92  ? 138.087 120.325 202.976 1.00 121.32 ? 83  VAL R C   1 
ATOM   6290 O O   . VAL F 6 92  ? 138.805 119.747 202.152 1.00 121.32 ? 83  VAL R O   1 
ATOM   6291 C CB  . VAL F 6 92  ? 139.128 122.554 203.535 1.00 121.32 ? 83  VAL R CB  1 
ATOM   6292 N N   . SER F 6 93  ? 136.759 120.252 202.964 1.00 118.53 ? 84  SER R N   1 
ATOM   6293 C CA  . SER F 6 93  ? 136.064 119.465 201.955 1.00 118.53 ? 84  SER R CA  1 
ATOM   6294 C C   . SER F 6 93  ? 136.365 120.002 200.562 1.00 118.53 ? 84  SER R C   1 
ATOM   6295 O O   . SER F 6 93  ? 136.533 121.209 200.364 1.00 118.53 ? 84  SER R O   1 
ATOM   6296 C CB  . SER F 6 93  ? 134.557 119.485 202.215 1.00 118.53 ? 84  SER R CB  1 
ATOM   6297 N N   . CYS F 6 94  ? 136.436 119.095 199.594 1.00 116.48 ? 85  CYS R N   1 
ATOM   6298 C CA  . CYS F 6 94  ? 136.763 119.492 198.235 1.00 116.48 ? 85  CYS R CA  1 
ATOM   6299 C C   . CYS F 6 94  ? 135.704 120.461 197.709 1.00 116.48 ? 85  CYS R C   1 
ATOM   6300 O O   . CYS F 6 94  ? 134.511 120.283 197.984 1.00 116.48 ? 85  CYS R O   1 
ATOM   6301 C CB  . CYS F 6 94  ? 136.848 118.264 197.327 1.00 116.48 ? 85  CYS R CB  1 
ATOM   6302 S SG  . CYS F 6 94  ? 137.787 118.523 195.806 1.00 116.48 ? 85  CYS R SG  1 
ATOM   6303 N N   . PRO F 6 95  ? 136.094 121.492 196.957 1.00 116.49 ? 86  PRO R N   1 
ATOM   6304 C CA  . PRO F 6 95  ? 135.096 122.443 196.454 1.00 116.49 ? 86  PRO R CA  1 
ATOM   6305 C C   . PRO F 6 95  ? 134.095 121.765 195.530 1.00 116.49 ? 86  PRO R C   1 
ATOM   6306 O O   . PRO F 6 95  ? 134.414 120.803 194.827 1.00 116.49 ? 86  PRO R O   1 
ATOM   6307 C CB  . PRO F 6 95  ? 135.933 123.488 195.706 1.00 116.49 ? 86  PRO R CB  1 
ATOM   6308 C CG  . PRO F 6 95  ? 137.331 123.294 196.172 1.00 116.49 ? 86  PRO R CG  1 
ATOM   6309 C CD  . PRO F 6 95  ? 137.459 121.858 196.542 1.00 116.49 ? 86  PRO R CD  1 
ATOM   6310 N N   . TRP F 6 96  ? 132.866 122.284 195.542 1.00 113.54 ? 87  TRP R N   1 
ATOM   6311 C CA  . TRP F 6 96  ? 131.782 121.704 194.759 1.00 113.54 ? 87  TRP R CA  1 
ATOM   6312 C C   . TRP F 6 96  ? 131.605 122.357 193.395 1.00 113.54 ? 87  TRP R C   1 
ATOM   6313 O O   . TRP F 6 96  ? 130.913 121.792 192.541 1.00 113.54 ? 87  TRP R O   1 
ATOM   6314 C CB  . TRP F 6 96  ? 130.461 121.802 195.533 1.00 113.54 ? 87  TRP R CB  1 
ATOM   6315 C CG  . TRP F 6 96  ? 130.128 123.192 195.994 1.00 113.54 ? 87  TRP R CG  1 
ATOM   6316 C CD1 . TRP F 6 96  ? 130.337 123.714 197.237 1.00 113.54 ? 87  TRP R CD1 1 
ATOM   6317 C CD2 . TRP F 6 96  ? 129.526 124.235 195.217 1.00 113.54 ? 87  TRP R CD2 1 
ATOM   6318 N NE1 . TRP F 6 96  ? 129.903 125.018 197.282 1.00 113.54 ? 87  TRP R NE1 1 
ATOM   6319 C CE2 . TRP F 6 96  ? 129.401 125.361 196.055 1.00 113.54 ? 87  TRP R CE2 1 
ATOM   6320 C CE3 . TRP F 6 96  ? 129.081 124.326 193.895 1.00 113.54 ? 87  TRP R CE3 1 
ATOM   6321 C CZ2 . TRP F 6 96  ? 128.851 126.562 195.614 1.00 113.54 ? 87  TRP R CZ2 1 
ATOM   6322 C CZ3 . TRP F 6 96  ? 128.534 125.521 193.459 1.00 113.54 ? 87  TRP R CZ3 1 
ATOM   6323 C CH2 . TRP F 6 96  ? 128.424 126.622 194.316 1.00 113.54 ? 87  TRP R CH2 1 
ATOM   6324 N N   . TYR F 6 97  ? 132.206 123.526 193.168 1.00 114.47 ? 88  TYR R N   1 
ATOM   6325 C CA  . TYR F 6 97  ? 132.020 124.238 191.911 1.00 114.47 ? 88  TYR R CA  1 
ATOM   6326 C C   . TYR F 6 97  ? 132.934 123.740 190.800 1.00 114.47 ? 88  TYR R C   1 
ATOM   6327 O O   . TYR F 6 97  ? 132.780 124.177 189.653 1.00 114.47 ? 88  TYR R O   1 
ATOM   6328 C CB  . TYR F 6 97  ? 132.249 125.739 192.116 1.00 114.47 ? 88  TYR R CB  1 
ATOM   6329 N N   . LEU F 6 98  ? 133.874 122.848 191.100 1.00 106.57 ? 89  LEU R N   1 
ATOM   6330 C CA  . LEU F 6 98  ? 134.791 122.374 190.080 1.00 106.57 ? 89  LEU R CA  1 
ATOM   6331 C C   . LEU F 6 98  ? 134.037 121.563 189.026 1.00 106.57 ? 89  LEU R C   1 
ATOM   6332 O O   . LEU F 6 98  ? 133.034 120.912 189.331 1.00 106.57 ? 89  LEU R O   1 
ATOM   6333 C CB  . LEU F 6 98  ? 135.889 121.516 190.702 1.00 106.57 ? 89  LEU R CB  1 
ATOM   6334 C CG  . LEU F 6 98  ? 136.625 122.125 191.897 1.00 106.57 ? 89  LEU R CG  1 
ATOM   6335 C CD1 . LEU F 6 98  ? 137.678 121.162 192.418 1.00 106.57 ? 89  LEU R CD1 1 
ATOM   6336 C CD2 . LEU F 6 98  ? 137.257 123.455 191.520 1.00 106.57 ? 89  LEU R CD2 1 
ATOM   6337 N N   . PRO F 6 99  ? 134.498 121.586 187.771 1.00 101.26 ? 90  PRO R N   1 
ATOM   6338 C CA  . PRO F 6 99  ? 133.831 120.769 186.744 1.00 101.26 ? 90  PRO R CA  1 
ATOM   6339 C C   . PRO F 6 99  ? 133.802 119.291 187.086 1.00 101.26 ? 90  PRO R C   1 
ATOM   6340 O O   . PRO F 6 99  ? 132.829 118.604 186.751 1.00 101.26 ? 90  PRO R O   1 
ATOM   6341 C CB  . PRO F 6 99  ? 134.660 121.040 185.480 1.00 101.26 ? 90  PRO R CB  1 
ATOM   6342 N N   . TRP F 6 100 ? 134.840 118.783 187.746 1.00 99.65  ? 91  TRP R N   1 
ATOM   6343 C CA  . TRP F 6 100 ? 134.928 117.379 188.120 1.00 99.65  ? 91  TRP R CA  1 
ATOM   6344 C C   . TRP F 6 100 ? 134.491 117.131 189.558 1.00 99.65  ? 91  TRP R C   1 
ATOM   6345 O O   . TRP F 6 100 ? 134.720 116.037 190.084 1.00 99.65  ? 91  TRP R O   1 
ATOM   6346 C CB  . TRP F 6 100 ? 136.357 116.869 187.919 1.00 99.65  ? 91  TRP R CB  1 
ATOM   6347 C CG  . TRP F 6 100 ? 137.389 117.687 188.631 1.00 99.65  ? 91  TRP R CG  1 
ATOM   6348 C CD1 . TRP F 6 100 ? 137.822 117.526 189.914 1.00 99.65  ? 91  TRP R CD1 1 
ATOM   6349 C CD2 . TRP F 6 100 ? 138.114 118.802 188.099 1.00 99.65  ? 91  TRP R CD2 1 
ATOM   6350 N NE1 . TRP F 6 100 ? 138.773 118.470 190.215 1.00 99.65  ? 91  TRP R NE1 1 
ATOM   6351 C CE2 . TRP F 6 100 ? 138.971 119.265 189.117 1.00 99.65  ? 91  TRP R CE2 1 
ATOM   6352 C CE3 . TRP F 6 100 ? 138.123 119.452 186.861 1.00 99.65  ? 91  TRP R CE3 1 
ATOM   6353 C CZ2 . TRP F 6 100 ? 139.827 120.348 188.935 1.00 99.65  ? 91  TRP R CZ2 1 
ATOM   6354 C CZ3 . TRP F 6 100 ? 138.974 120.526 186.683 1.00 99.65  ? 91  TRP R CZ3 1 
ATOM   6355 C CH2 . TRP F 6 100 ? 139.814 120.963 187.714 1.00 99.65  ? 91  TRP R CH2 1 
ATOM   6356 N N   . ALA F 6 101 ? 133.870 118.119 190.205 1.00 101.49 ? 92  ALA R N   1 
ATOM   6357 C CA  . ALA F 6 101 ? 133.433 117.934 191.586 1.00 101.49 ? 92  ALA R CA  1 
ATOM   6358 C C   . ALA F 6 101 ? 132.427 116.795 191.694 1.00 101.49 ? 92  ALA R C   1 
ATOM   6359 O O   . ALA F 6 101 ? 132.501 115.978 192.620 1.00 101.49 ? 92  ALA R O   1 
ATOM   6360 C CB  . ALA F 6 101 ? 132.832 119.232 192.123 1.00 101.49 ? 92  ALA R CB  1 
ATOM   6361 N N   . SER F 6 102 ? 131.480 116.724 190.758 1.00 94.99  ? 93  SER R N   1 
ATOM   6362 C CA  . SER F 6 102 ? 130.503 115.642 190.780 1.00 94.99  ? 93  SER R CA  1 
ATOM   6363 C C   . SER F 6 102 ? 131.176 114.289 190.591 1.00 94.99  ? 93  SER R C   1 
ATOM   6364 O O   . SER F 6 102 ? 130.789 113.300 191.224 1.00 94.99  ? 93  SER R O   1 
ATOM   6365 C CB  . SER F 6 102 ? 129.447 115.870 189.698 1.00 94.99  ? 93  SER R CB  1 
ATOM   6366 N N   . SER F 6 103 ? 132.181 114.222 189.714 1.00 93.11  ? 94  SER R N   1 
ATOM   6367 C CA  . SER F 6 103 ? 132.855 112.953 189.461 1.00 93.11  ? 94  SER R CA  1 
ATOM   6368 C C   . SER F 6 103 ? 133.548 112.432 190.714 1.00 93.11  ? 94  SER R C   1 
ATOM   6369 O O   . SER F 6 103 ? 133.470 111.238 191.025 1.00 93.11  ? 94  SER R O   1 
ATOM   6370 C CB  . SER F 6 103 ? 133.861 113.115 188.322 1.00 93.11  ? 94  SER R CB  1 
ATOM   6371 N N   . VAL F 6 104 ? 134.230 113.310 191.446 1.00 94.31  ? 95  VAL R N   1 
ATOM   6372 C CA  . VAL F 6 104 ? 134.956 112.916 192.652 1.00 94.31  ? 95  VAL R CA  1 
ATOM   6373 C C   . VAL F 6 104 ? 134.607 113.882 193.778 1.00 94.31  ? 95  VAL R C   1 
ATOM   6374 O O   . VAL F 6 104 ? 135.448 114.699 194.183 1.00 94.31  ? 95  VAL R O   1 
ATOM   6375 C CB  . VAL F 6 104 ? 136.474 112.863 192.393 1.00 94.31  ? 95  VAL R CB  1 
ATOM   6376 N N   . PRO F 6 105 ? 133.386 113.831 194.316 1.00 94.51  ? 96  PRO R N   1 
ATOM   6377 C CA  . PRO F 6 105 ? 133.037 114.743 195.418 1.00 94.51  ? 96  PRO R CA  1 
ATOM   6378 C C   . PRO F 6 105 ? 133.860 114.520 196.672 1.00 94.51  ? 96  PRO R C   1 
ATOM   6379 O O   . PRO F 6 105 ? 133.959 115.433 197.501 1.00 94.51  ? 96  PRO R O   1 
ATOM   6380 C CB  . PRO F 6 105 ? 131.547 114.450 195.666 1.00 94.51  ? 96  PRO R CB  1 
ATOM   6381 C CG  . PRO F 6 105 ? 131.089 113.615 194.505 1.00 94.51  ? 96  PRO R CG  1 
ATOM   6382 C CD  . PRO F 6 105 ? 132.294 112.898 194.003 1.00 94.51  ? 96  PRO R CD  1 
ATOM   6383 N N   . GLN F 6 106 ? 134.454 113.341 196.839 1.00 93.31  ? 97  GLN R N   1 
ATOM   6384 C CA  . GLN F 6 106 ? 135.224 113.036 198.034 1.00 93.31  ? 97  GLN R CA  1 
ATOM   6385 C C   . GLN F 6 106 ? 136.584 113.730 197.978 1.00 93.31  ? 97  GLN R C   1 
ATOM   6386 O O   . GLN F 6 106 ? 136.901 114.468 197.041 1.00 93.31  ? 97  GLN R O   1 
ATOM   6387 C CB  . GLN F 6 106 ? 135.385 111.526 198.188 1.00 93.31  ? 97  GLN R CB  1 
ATOM   6388 N N   . GLY F 6 107 ? 137.396 113.487 198.995 1.00 107.14 ? 98  GLY R N   1 
ATOM   6389 C CA  . GLY F 6 107 ? 138.710 114.103 199.082 1.00 107.14 ? 98  GLY R CA  1 
ATOM   6390 C C   . GLY F 6 107 ? 138.694 115.378 199.901 1.00 107.14 ? 98  GLY R C   1 
ATOM   6391 O O   . GLY F 6 107 ? 137.698 116.098 199.975 1.00 107.14 ? 98  GLY R O   1 
ATOM   6392 N N   . HIS F 6 108 ? 139.830 115.659 200.535 1.00 117.65 ? 99  HIS R N   1 
ATOM   6393 C CA  . HIS F 6 108 ? 139.983 116.844 201.371 1.00 117.65 ? 99  HIS R CA  1 
ATOM   6394 C C   . HIS F 6 108 ? 141.320 117.495 201.059 1.00 117.65 ? 99  HIS R C   1 
ATOM   6395 O O   . HIS F 6 108 ? 142.367 116.848 201.164 1.00 117.65 ? 99  HIS R O   1 
ATOM   6396 C CB  . HIS F 6 108 ? 139.896 116.486 202.859 1.00 117.65 ? 99  HIS R CB  1 
ATOM   6397 N N   . VAL F 6 109 ? 141.284 118.770 200.675 1.00 119.74 ? 100 VAL R N   1 
ATOM   6398 C CA  . VAL F 6 109 ? 142.510 119.515 200.424 1.00 119.74 ? 100 VAL R CA  1 
ATOM   6399 C C   . VAL F 6 109 ? 143.252 119.710 201.739 1.00 119.74 ? 100 VAL R C   1 
ATOM   6400 O O   . VAL F 6 109 ? 142.662 120.112 202.750 1.00 119.74 ? 100 VAL R O   1 
ATOM   6401 C CB  . VAL F 6 109 ? 142.192 120.856 199.746 1.00 119.74 ? 100 VAL R CB  1 
ATOM   6402 N N   . TYR F 6 110 ? 144.551 119.425 201.731 1.00 119.79 ? 101 TYR R N   1 
ATOM   6403 C CA  . TYR F 6 110 ? 145.374 119.452 202.932 1.00 119.79 ? 101 TYR R CA  1 
ATOM   6404 C C   . TYR F 6 110 ? 146.360 120.610 202.874 1.00 119.79 ? 101 TYR R C   1 
ATOM   6405 O O   . TYR F 6 110 ? 147.010 120.839 201.849 1.00 119.79 ? 101 TYR R O   1 
ATOM   6406 C CB  . TYR F 6 110 ? 146.138 118.136 203.101 1.00 119.79 ? 101 TYR R CB  1 
ATOM   6407 N N   . ARG F 6 111 ? 146.464 121.338 203.985 1.00 120.27 ? 102 ARG R N   1 
ATOM   6408 C CA  . ARG F 6 111 ? 147.418 122.429 204.122 1.00 120.27 ? 102 ARG R CA  1 
ATOM   6409 C C   . ARG F 6 111 ? 147.921 122.437 205.558 1.00 120.27 ? 102 ARG R C   1 
ATOM   6410 O O   . ARG F 6 111 ? 147.134 122.289 206.496 1.00 120.27 ? 102 ARG R O   1 
ATOM   6411 C CB  . ARG F 6 111 ? 146.780 123.776 203.759 1.00 120.27 ? 102 ARG R CB  1 
ATOM   6412 N N   . PHE F 6 112 ? 149.229 122.613 205.721 1.00 120.62 ? 103 PHE R N   1 
ATOM   6413 C CA  . PHE F 6 112 ? 149.875 122.509 207.022 1.00 120.62 ? 103 PHE R CA  1 
ATOM   6414 C C   . PHE F 6 112 ? 149.995 123.881 207.670 1.00 120.62 ? 103 PHE R C   1 
ATOM   6415 O O   . PHE F 6 112 ? 150.385 124.856 207.020 1.00 120.62 ? 103 PHE R O   1 
ATOM   6416 C CB  . PHE F 6 112 ? 151.261 121.874 206.888 1.00 120.62 ? 103 PHE R CB  1 
ATOM   6417 N N   . CYS F 6 113 ? 149.659 123.947 208.956 1.00 119.15 ? 104 CYS R N   1 
ATOM   6418 C CA  . CYS F 6 113 ? 149.736 125.172 209.741 1.00 119.15 ? 104 CYS R CA  1 
ATOM   6419 C C   . CYS F 6 113 ? 150.742 124.982 210.866 1.00 119.15 ? 104 CYS R C   1 
ATOM   6420 O O   . CYS F 6 113 ? 150.689 123.982 211.588 1.00 119.15 ? 104 CYS R O   1 
ATOM   6421 C CB  . CYS F 6 113 ? 148.365 125.545 210.312 1.00 119.15 ? 104 CYS R CB  1 
ATOM   6422 S SG  . CYS F 6 113 ? 148.421 126.769 211.641 1.00 119.15 ? 104 CYS R SG  1 
ATOM   6423 N N   . THR F 6 114 ? 151.653 125.940 211.011 1.00 116.39 ? 105 THR R N   1 
ATOM   6424 C CA  . THR F 6 114 ? 152.671 125.863 212.046 1.00 116.39 ? 105 THR R CA  1 
ATOM   6425 C C   . THR F 6 114 ? 152.084 126.232 213.406 1.00 116.39 ? 105 THR R C   1 
ATOM   6426 O O   . THR F 6 114 ? 150.991 126.794 213.513 1.00 116.39 ? 105 THR R O   1 
ATOM   6427 C CB  . THR F 6 114 ? 153.848 126.786 211.724 1.00 116.39 ? 105 THR R CB  1 
ATOM   6428 N N   . ALA F 6 115 ? 152.837 125.904 214.458 1.00 106.91 ? 106 ALA R N   1 
ATOM   6429 C CA  . ALA F 6 115 ? 152.378 126.180 215.814 1.00 106.91 ? 106 ALA R CA  1 
ATOM   6430 C C   . ALA F 6 115 ? 152.229 127.678 216.054 1.00 106.91 ? 106 ALA R C   1 
ATOM   6431 O O   . ALA F 6 115 ? 151.306 128.114 216.752 1.00 106.91 ? 106 ALA R O   1 
ATOM   6432 C CB  . ALA F 6 115 ? 153.344 125.569 216.828 1.00 106.91 ? 106 ALA R CB  1 
ATOM   6433 N N   . GLU F 6 116 ? 153.125 128.480 215.486 1.00 109.08 ? 107 GLU R N   1 
ATOM   6434 C CA  . GLU F 6 116 ? 153.126 129.927 215.700 1.00 109.08 ? 107 GLU R CA  1 
ATOM   6435 C C   . GLU F 6 116 ? 151.995 130.647 214.966 1.00 109.08 ? 107 GLU R C   1 
ATOM   6436 O O   . GLU F 6 116 ? 151.997 131.886 214.964 1.00 109.08 ? 107 GLU R O   1 
ATOM   6437 C CB  . GLU F 6 116 ? 154.473 130.511 215.272 1.00 109.08 ? 107 GLU R CB  1 
ATOM   6438 N N   . GLY F 6 117 ? 151.042 129.949 214.351 1.00 111.33 ? 108 GLY R N   1 
ATOM   6439 C CA  . GLY F 6 117 ? 149.972 130.593 213.621 1.00 111.33 ? 108 GLY R CA  1 
ATOM   6440 C C   . GLY F 6 117 ? 150.277 130.882 212.169 1.00 111.33 ? 108 GLY R C   1 
ATOM   6441 O O   . GLY F 6 117 ? 149.388 131.360 211.450 1.00 111.33 ? 108 GLY R O   1 
ATOM   6442 N N   . LEU F 6 118 ? 151.496 130.615 211.713 1.00 115.17 ? 109 LEU R N   1 
ATOM   6443 C CA  . LEU F 6 118 ? 151.870 130.817 210.321 1.00 115.17 ? 109 LEU R CA  1 
ATOM   6444 C C   . LEU F 6 118 ? 151.724 129.510 209.556 1.00 115.17 ? 109 LEU R C   1 
ATOM   6445 O O   . LEU F 6 118 ? 152.110 128.446 210.044 1.00 115.17 ? 109 LEU R O   1 
ATOM   6446 C CB  . LEU F 6 118 ? 153.308 131.326 210.218 1.00 115.17 ? 109 LEU R CB  1 
ATOM   6447 N N   . TRP F 6 119 ? 151.157 129.594 208.356 1.00 120.74 ? 110 TRP R N   1 
ATOM   6448 C CA  . TRP F 6 119 ? 150.970 128.398 207.549 1.00 120.74 ? 110 TRP R CA  1 
ATOM   6449 C C   . TRP F 6 119 ? 152.322 127.824 207.143 1.00 120.74 ? 110 TRP R C   1 
ATOM   6450 O O   . TRP F 6 119 ? 153.229 128.555 206.735 1.00 120.74 ? 110 TRP R O   1 
ATOM   6451 C CB  . TRP F 6 119 ? 150.136 128.713 206.309 1.00 120.74 ? 110 TRP R CB  1 
ATOM   6452 N N   . LEU F 6 120 ? 152.454 126.505 207.260 1.00 118.12 ? 111 LEU R N   1 
ATOM   6453 C CA  . LEU F 6 120 ? 153.725 125.854 206.970 1.00 118.12 ? 111 LEU R CA  1 
ATOM   6454 C C   . LEU F 6 120 ? 154.147 126.127 205.533 1.00 118.12 ? 111 LEU R C   1 
ATOM   6455 O O   . LEU F 6 120 ? 153.363 125.954 204.596 1.00 118.12 ? 111 LEU R O   1 
ATOM   6456 C CB  . LEU F 6 120 ? 153.610 124.348 207.211 1.00 118.12 ? 111 LEU R CB  1 
ATOM   6457 N N   . GLN F 6 121 ? 155.396 126.551 205.364 1.00 112.48 ? 112 GLN R N   1 
ATOM   6458 C CA  . GLN F 6 121 ? 155.916 126.840 204.035 1.00 112.48 ? 112 GLN R CA  1 
ATOM   6459 C C   . GLN F 6 121 ? 156.120 125.551 203.251 1.00 112.48 ? 112 GLN R C   1 
ATOM   6460 O O   . GLN F 6 121 ? 156.538 124.527 203.802 1.00 112.48 ? 112 GLN R O   1 
ATOM   6461 C CB  . GLN F 6 121 ? 157.234 127.606 204.137 1.00 112.48 ? 112 GLN R CB  1 
ATOM   6462 N N   . LYS F 6 122 ? 155.820 125.603 201.957 1.00 106.21 ? 113 LYS R N   1 
ATOM   6463 C CA  . LYS F 6 122 ? 156.012 124.446 201.100 1.00 106.21 ? 113 LYS R CA  1 
ATOM   6464 C C   . LYS F 6 122 ? 157.504 124.186 200.893 1.00 106.21 ? 113 LYS R C   1 
ATOM   6465 O O   . LYS F 6 122 ? 158.362 125.014 201.213 1.00 106.21 ? 113 LYS R O   1 
ATOM   6466 C CB  . LYS F 6 122 ? 155.311 124.650 199.758 1.00 106.21 ? 113 LYS R CB  1 
ATOM   6467 N N   . ASP F 6 123 ? 157.809 123.010 200.347 1.00 92.21  ? 114 ASP R N   1 
ATOM   6468 C CA  . ASP F 6 123 ? 159.193 122.585 200.183 1.00 92.21  ? 114 ASP R CA  1 
ATOM   6469 C C   . ASP F 6 123 ? 159.959 123.539 199.276 1.00 92.21  ? 114 ASP R C   1 
ATOM   6470 O O   . ASP F 6 123 ? 159.711 123.594 198.067 1.00 92.21  ? 114 ASP R O   1 
ATOM   6471 C CB  . ASP F 6 123 ? 159.249 121.164 199.619 1.00 92.21  ? 114 ASP R CB  1 
ATOM   6472 N N   . ASN F 6 124 ? 160.897 124.290 199.855 1.00 94.84  ? 115 ASN R N   1 
ATOM   6473 C CA  . ASN F 6 124 ? 161.762 125.190 199.095 1.00 94.84  ? 115 ASN R CA  1 
ATOM   6474 C C   . ASN F 6 124 ? 160.944 126.158 198.243 1.00 94.84  ? 115 ASN R C   1 
ATOM   6475 O O   . ASN F 6 124 ? 161.297 126.468 197.102 1.00 94.84  ? 115 ASN R O   1 
ATOM   6476 C CB  . ASN F 6 124 ? 162.739 124.397 198.225 1.00 94.84  ? 115 ASN R CB  1 
ATOM   6477 N N   . SER F 6 125 ? 159.839 126.643 198.804 1.00 99.58  ? 116 SER R N   1 
ATOM   6478 C CA  . SER F 6 125 ? 158.986 127.592 198.104 1.00 99.58  ? 116 SER R CA  1 
ATOM   6479 C C   . SER F 6 125 ? 158.310 128.501 199.118 1.00 99.58  ? 116 SER R C   1 
ATOM   6480 O O   . SER F 6 125 ? 158.073 128.111 200.265 1.00 99.58  ? 116 SER R O   1 
ATOM   6481 C CB  . SER F 6 125 ? 157.935 126.878 197.246 1.00 99.58  ? 116 SER R CB  1 
ATOM   6482 N N   . SER F 6 126 ? 158.000 129.723 198.679 1.00 104.54 ? 117 SER R N   1 
ATOM   6483 C CA  . SER F 6 126 ? 157.344 130.683 199.558 1.00 104.54 ? 117 SER R CA  1 
ATOM   6484 C C   . SER F 6 126 ? 155.905 130.282 199.861 1.00 104.54 ? 117 SER R C   1 
ATOM   6485 O O   . SER F 6 126 ? 155.413 130.535 200.966 1.00 104.54 ? 117 SER R O   1 
ATOM   6486 C CB  . SER F 6 126 ? 157.379 132.076 198.932 1.00 104.54 ? 117 SER R CB  1 
ATOM   6487 N N   . LEU F 6 127 ? 155.222 129.663 198.904 1.00 104.86 ? 118 LEU R N   1 
ATOM   6488 C CA  . LEU F 6 127 ? 153.823 129.322 199.103 1.00 104.86 ? 118 LEU R CA  1 
ATOM   6489 C C   . LEU F 6 127 ? 153.685 128.330 200.257 1.00 104.86 ? 118 LEU R C   1 
ATOM   6490 O O   . LEU F 6 127 ? 154.533 127.443 200.417 1.00 104.86 ? 118 LEU R O   1 
ATOM   6491 C CB  . LEU F 6 127 ? 153.232 128.721 197.826 1.00 104.86 ? 118 LEU R CB  1 
ATOM   6492 N N   . PRO F 6 128 ? 152.643 128.446 201.080 1.00 110.13 ? 119 PRO R N   1 
ATOM   6493 C CA  . PRO F 6 128 ? 152.442 127.455 202.144 1.00 110.13 ? 119 PRO R CA  1 
ATOM   6494 C C   . PRO F 6 128 ? 152.219 126.066 201.569 1.00 110.13 ? 119 PRO R C   1 
ATOM   6495 O O   . PRO F 6 128 ? 151.650 125.900 200.488 1.00 110.13 ? 119 PRO R O   1 
ATOM   6496 C CB  . PRO F 6 128 ? 151.199 127.964 202.883 1.00 110.13 ? 119 PRO R CB  1 
ATOM   6497 N N   . TRP F 6 129 ? 152.679 125.058 202.310 1.00 115.45 ? 120 TRP R N   1 
ATOM   6498 C CA  . TRP F 6 129 ? 152.514 123.681 201.868 1.00 115.45 ? 120 TRP R CA  1 
ATOM   6499 C C   . TRP F 6 129 ? 151.037 123.360 201.684 1.00 115.45 ? 120 TRP R C   1 
ATOM   6500 O O   . TRP F 6 129 ? 150.214 123.637 202.561 1.00 115.45 ? 120 TRP R O   1 
ATOM   6501 C CB  . TRP F 6 129 ? 153.132 122.720 202.882 1.00 115.45 ? 120 TRP R CB  1 
ATOM   6502 C CG  . TRP F 6 129 ? 153.031 121.287 202.464 1.00 115.45 ? 120 TRP R CG  1 
ATOM   6503 C CD1 . TRP F 6 129 ? 153.787 120.652 201.524 1.00 115.45 ? 120 TRP R CD1 1 
ATOM   6504 C CD2 . TRP F 6 129 ? 152.106 120.312 202.960 1.00 115.45 ? 120 TRP R CD2 1 
ATOM   6505 N NE1 . TRP F 6 129 ? 153.398 119.340 201.408 1.00 115.45 ? 120 TRP R NE1 1 
ATOM   6506 C CE2 . TRP F 6 129 ? 152.366 119.105 202.280 1.00 115.45 ? 120 TRP R CE2 1 
ATOM   6507 C CE3 . TRP F 6 129 ? 151.087 120.340 203.916 1.00 115.45 ? 120 TRP R CE3 1 
ATOM   6508 C CZ2 . TRP F 6 129 ? 151.645 117.939 202.524 1.00 115.45 ? 120 TRP R CZ2 1 
ATOM   6509 C CZ3 . TRP F 6 129 ? 150.371 119.181 204.158 1.00 115.45 ? 120 TRP R CZ3 1 
ATOM   6510 C CH2 . TRP F 6 129 ? 150.654 117.997 203.465 1.00 115.45 ? 120 TRP R CH2 1 
ATOM   6511 N N   . ARG F 6 130 ? 150.703 122.769 200.539 1.00 117.41 ? 121 ARG R N   1 
ATOM   6512 C CA  . ARG F 6 130 ? 149.330 122.410 200.221 1.00 117.41 ? 121 ARG R CA  1 
ATOM   6513 C C   . ARG F 6 130 ? 149.317 121.087 199.470 1.00 117.41 ? 121 ARG R C   1 
ATOM   6514 O O   . ARG F 6 130 ? 150.277 120.741 198.776 1.00 117.41 ? 121 ARG R O   1 
ATOM   6515 C CB  . ARG F 6 130 ? 148.642 123.495 199.379 1.00 117.41 ? 121 ARG R CB  1 
ATOM   6516 C CG  . ARG F 6 130 ? 148.392 124.798 200.124 1.00 117.41 ? 121 ARG R CG  1 
ATOM   6517 C CD  . ARG F 6 130 ? 148.295 125.981 199.173 1.00 117.41 ? 121 ARG R CD  1 
ATOM   6518 N NE  . ARG F 6 130 ? 147.013 126.021 198.478 1.00 117.41 ? 121 ARG R NE  1 
ATOM   6519 C CZ  . ARG F 6 130 ? 146.816 125.642 197.221 1.00 117.41 ? 121 ARG R CZ  1 
ATOM   6520 N NH1 . ARG F 6 130 ? 147.801 125.166 196.474 1.00 117.41 ? 121 ARG R NH1 1 
ATOM   6521 N NH2 . ARG F 6 130 ? 145.597 125.741 196.698 1.00 117.41 ? 121 ARG R NH2 1 
ATOM   6522 N N   . ASP F 6 131 ? 148.219 120.351 199.620 1.00 113.66 ? 122 ASP R N   1 
ATOM   6523 C CA  . ASP F 6 131 ? 148.012 119.084 198.929 1.00 113.66 ? 122 ASP R CA  1 
ATOM   6524 C C   . ASP F 6 131 ? 146.705 119.166 198.155 1.00 113.66 ? 122 ASP R C   1 
ATOM   6525 O O   . ASP F 6 131 ? 145.641 119.376 198.749 1.00 113.66 ? 122 ASP R O   1 
ATOM   6526 C CB  . ASP F 6 131 ? 147.983 117.916 199.917 1.00 113.66 ? 122 ASP R CB  1 
ATOM   6527 N N   . LEU F 6 132 ? 146.786 118.998 196.834 1.00 113.68 ? 123 LEU R N   1 
ATOM   6528 C CA  . LEU F 6 132 ? 145.622 119.102 195.966 1.00 113.68 ? 123 LEU R CA  1 
ATOM   6529 C C   . LEU F 6 132 ? 145.437 117.913 195.035 1.00 113.68 ? 123 LEU R C   1 
ATOM   6530 O O   . LEU F 6 132 ? 144.425 117.864 194.329 1.00 113.68 ? 123 LEU R O   1 
ATOM   6531 C CB  . LEU F 6 132 ? 145.701 120.379 195.115 1.00 113.68 ? 123 LEU R CB  1 
ATOM   6532 N N   . SER F 6 133 ? 146.371 116.958 195.008 1.00 107.56 ? 124 SER R N   1 
ATOM   6533 C CA  . SER F 6 133 ? 146.244 115.829 194.093 1.00 107.56 ? 124 SER R CA  1 
ATOM   6534 C C   . SER F 6 133 ? 144.960 115.048 194.339 1.00 107.56 ? 124 SER R C   1 
ATOM   6535 O O   . SER F 6 133 ? 144.416 114.440 193.411 1.00 107.56 ? 124 SER R O   1 
ATOM   6536 C CB  . SER F 6 133 ? 147.457 114.908 194.228 1.00 107.56 ? 124 SER R CB  1 
ATOM   6537 N N   . GLU F 6 134 ? 144.462 115.050 195.578 1.00 111.88 ? 125 GLU R N   1 
ATOM   6538 C CA  . GLU F 6 134 ? 143.226 114.333 195.874 1.00 111.88 ? 125 GLU R CA  1 
ATOM   6539 C C   . GLU F 6 134 ? 142.047 114.907 195.098 1.00 111.88 ? 125 GLU R C   1 
ATOM   6540 O O   . GLU F 6 134 ? 141.196 114.150 194.617 1.00 111.88 ? 125 GLU R O   1 
ATOM   6541 C CB  . GLU F 6 134 ? 142.944 114.364 197.378 1.00 111.88 ? 125 GLU R CB  1 
ATOM   6542 N N   . CYS F 6 135 ? 141.977 116.231 194.965 1.00 112.19 ? 126 CYS R N   1 
ATOM   6543 C CA  . CYS F 6 135 ? 140.888 116.878 194.247 1.00 112.19 ? 126 CYS R CA  1 
ATOM   6544 C C   . CYS F 6 135 ? 141.137 116.986 192.749 1.00 112.19 ? 126 CYS R C   1 
ATOM   6545 O O   . CYS F 6 135 ? 140.210 117.335 192.008 1.00 112.19 ? 126 CYS R O   1 
ATOM   6546 C CB  . CYS F 6 135 ? 140.643 118.279 194.819 1.00 112.19 ? 126 CYS R CB  1 
ATOM   6547 S SG  . CYS F 6 135 ? 139.724 118.295 196.374 1.00 112.19 ? 126 CYS R SG  1 
ATOM   6548 N N   . GLU F 6 136 ? 142.349 116.698 192.285 1.00 106.82 ? 127 GLU R N   1 
ATOM   6549 C CA  . GLU F 6 136 ? 142.649 116.797 190.864 1.00 106.82 ? 127 GLU R CA  1 
ATOM   6550 C C   . GLU F 6 136 ? 141.909 115.719 190.079 1.00 106.82 ? 127 GLU R C   1 
ATOM   6551 O O   . GLU F 6 136 ? 141.714 114.595 190.550 1.00 106.82 ? 127 GLU R O   1 
ATOM   6552 C CB  . GLU F 6 136 ? 144.153 116.673 190.625 1.00 106.82 ? 127 GLU R CB  1 
ATOM   6553 N N   . GLU F 6 137 ? 141.496 116.076 188.867 1.00 96.32  ? 128 GLU R N   1 
ATOM   6554 C CA  . GLU F 6 137 ? 140.795 115.134 188.008 1.00 96.32  ? 128 GLU R CA  1 
ATOM   6555 C C   . GLU F 6 137 ? 141.712 113.979 187.618 1.00 96.32  ? 128 GLU R C   1 
ATOM   6556 O O   . GLU F 6 137 ? 142.927 114.139 187.475 1.00 96.32  ? 128 GLU R O   1 
ATOM   6557 C CB  . GLU F 6 137 ? 140.272 115.837 186.753 1.00 96.32  ? 128 GLU R CB  1 
ATOM   6558 N N   . SER F 6 138 ? 141.114 112.803 187.450 1.00 81.60  ? 129 SER R N   1 
ATOM   6559 C CA  . SER F 6 138 ? 141.863 111.608 187.079 1.00 81.60  ? 129 SER R CA  1 
ATOM   6560 C C   . SER F 6 138 ? 142.602 111.809 185.760 1.00 81.60  ? 129 SER R C   1 
ATOM   6561 O O   . SER F 6 138 ? 142.359 112.779 185.042 1.00 81.60  ? 129 SER R O   1 
ATOM   6562 C CB  . SER F 6 138 ? 140.927 110.403 186.977 1.00 81.60  ? 129 SER R CB  1 
ATOM   6563 N N   . GLU F 6 147 ? 141.309 115.430 170.025 1.00 69.31  ? 138 GLU R N   1 
ATOM   6564 C CA  . GLU F 6 147 ? 141.349 116.563 169.113 1.00 69.31  ? 138 GLU R CA  1 
ATOM   6565 C C   . GLU F 6 147 ? 142.209 116.307 167.881 1.00 69.31  ? 138 GLU R C   1 
ATOM   6566 O O   . GLU F 6 147 ? 142.191 117.124 166.956 1.00 69.31  ? 138 GLU R O   1 
ATOM   6567 C CB  . GLU F 6 147 ? 141.864 117.810 169.843 1.00 69.31  ? 138 GLU R CB  1 
ATOM   6568 C CG  . GLU F 6 147 ? 143.268 117.671 170.419 1.00 69.31  ? 138 GLU R CG  1 
ATOM   6569 C CD  . GLU F 6 147 ? 143.959 119.009 170.594 1.00 69.31  ? 138 GLU R CD  1 
ATOM   6570 O OE1 . GLU F 6 147 ? 143.326 119.941 171.130 1.00 69.31  ? 138 GLU R OE1 1 
ATOM   6571 O OE2 . GLU F 6 147 ? 145.136 119.129 170.193 1.00 69.31  ? 138 GLU R OE2 1 
ATOM   6572 N N   . GLU F 6 148 ? 142.961 115.205 167.846 1.00 68.71  ? 139 GLU R N   1 
ATOM   6573 C CA  . GLU F 6 148 ? 143.803 114.926 166.687 1.00 68.71  ? 139 GLU R CA  1 
ATOM   6574 C C   . GLU F 6 148 ? 142.962 114.716 165.434 1.00 68.71  ? 139 GLU R C   1 
ATOM   6575 O O   . GLU F 6 148 ? 143.293 115.229 164.357 1.00 68.71  ? 139 GLU R O   1 
ATOM   6576 C CB  . GLU F 6 148 ? 144.672 113.700 166.960 1.00 68.71  ? 139 GLU R CB  1 
ATOM   6577 C CG  . GLU F 6 148 ? 145.675 113.393 165.863 1.00 68.71  ? 139 GLU R CG  1 
ATOM   6578 C CD  . GLU F 6 148 ? 146.860 112.593 166.367 1.00 68.71  ? 139 GLU R CD  1 
ATOM   6579 O OE1 . GLU F 6 148 ? 146.653 111.686 167.200 1.00 68.71  ? 139 GLU R OE1 1 
ATOM   6580 O OE2 . GLU F 6 148 ? 147.997 112.871 165.931 1.00 68.71  ? 139 GLU R OE2 1 
ATOM   6581 N N   . GLN F 6 149 ? 141.868 113.963 165.554 1.00 61.77  ? 140 GLN R N   1 
ATOM   6582 C CA  . GLN F 6 149 ? 140.994 113.758 164.406 1.00 61.77  ? 140 GLN R CA  1 
ATOM   6583 C C   . GLN F 6 149 ? 140.374 115.073 163.952 1.00 61.77  ? 140 GLN R C   1 
ATOM   6584 O O   . GLN F 6 149 ? 140.251 115.327 162.749 1.00 61.77  ? 140 GLN R O   1 
ATOM   6585 C CB  . GLN F 6 149 ? 139.911 112.734 164.746 1.00 61.77  ? 140 GLN R CB  1 
ATOM   6586 C CG  . GLN F 6 149 ? 138.862 113.230 165.725 1.00 61.77  ? 140 GLN R CG  1 
ATOM   6587 C CD  . GLN F 6 149 ? 138.042 112.101 166.317 1.00 61.77  ? 140 GLN R CD  1 
ATOM   6588 O OE1 . GLN F 6 149 ? 138.585 111.080 166.742 1.00 61.77  ? 140 GLN R OE1 1 
ATOM   6589 N NE2 . GLN F 6 149 ? 136.726 112.276 166.347 1.00 61.77  ? 140 GLN R NE2 1 
ATOM   6590 N N   . LEU F 6 150 ? 139.972 115.921 164.902 1.00 57.78  ? 141 LEU R N   1 
ATOM   6591 C CA  . LEU F 6 150 ? 139.427 117.223 164.535 1.00 57.78  ? 141 LEU R CA  1 
ATOM   6592 C C   . LEU F 6 150 ? 140.462 118.055 163.793 1.00 57.78  ? 141 LEU R C   1 
ATOM   6593 O O   . LEU F 6 150 ? 140.141 118.719 162.801 1.00 57.78  ? 141 LEU R O   1 
ATOM   6594 C CB  . LEU F 6 150 ? 138.942 117.961 165.783 1.00 57.78  ? 141 LEU R CB  1 
ATOM   6595 C CG  . LEU F 6 150 ? 137.987 117.197 166.703 1.00 57.78  ? 141 LEU R CG  1 
ATOM   6596 C CD1 . LEU F 6 150 ? 137.479 118.105 167.810 1.00 57.78  ? 141 LEU R CD1 1 
ATOM   6597 C CD2 . LEU F 6 150 ? 136.825 116.607 165.919 1.00 57.78  ? 141 LEU R CD2 1 
ATOM   6598 N N   . LEU F 6 151 ? 141.711 118.034 164.261 1.00 52.29  ? 142 LEU R N   1 
ATOM   6599 C CA  . LEU F 6 151 ? 142.765 118.784 163.588 1.00 52.29  ? 142 LEU R CA  1 
ATOM   6600 C C   . LEU F 6 151 ? 142.987 118.266 162.173 1.00 52.29  ? 142 LEU R C   1 
ATOM   6601 O O   . LEU F 6 151 ? 143.179 119.052 161.239 1.00 52.29  ? 142 LEU R O   1 
ATOM   6602 C CB  . LEU F 6 151 ? 144.059 118.705 164.397 1.00 52.29  ? 142 LEU R CB  1 
ATOM   6603 C CG  . LEU F 6 151 ? 145.190 119.628 163.943 1.00 52.29  ? 142 LEU R CG  1 
ATOM   6604 C CD1 . LEU F 6 151 ? 144.839 121.081 164.216 1.00 52.29  ? 142 LEU R CD1 1 
ATOM   6605 C CD2 . LEU F 6 151 ? 146.491 119.252 164.628 1.00 52.29  ? 142 LEU R CD2 1 
ATOM   6606 N N   . PHE F 6 152 ? 142.973 116.945 161.999 1.00 48.46  ? 143 PHE R N   1 
ATOM   6607 C CA  . PHE F 6 152 ? 143.119 116.376 160.662 1.00 48.46  ? 143 PHE R CA  1 
ATOM   6608 C C   . PHE F 6 152 ? 141.975 116.820 159.757 1.00 48.46  ? 143 PHE R C   1 
ATOM   6609 O O   . PHE F 6 152 ? 142.195 117.253 158.616 1.00 48.46  ? 143 PHE R O   1 
ATOM   6610 C CB  . PHE F 6 152 ? 143.175 114.851 160.757 1.00 48.46  ? 143 PHE R CB  1 
ATOM   6611 C CG  . PHE F 6 152 ? 143.847 114.188 159.589 1.00 48.46  ? 143 PHE R CG  1 
ATOM   6612 C CD1 . PHE F 6 152 ? 145.123 114.559 159.200 1.00 48.46  ? 143 PHE R CD1 1 
ATOM   6613 C CD2 . PHE F 6 152 ? 143.207 113.183 158.887 1.00 48.46  ? 143 PHE R CD2 1 
ATOM   6614 C CE1 . PHE F 6 152 ? 145.741 113.946 158.129 1.00 48.46  ? 143 PHE R CE1 1 
ATOM   6615 C CE2 . PHE F 6 152 ? 143.821 112.566 157.817 1.00 48.46  ? 143 PHE R CE2 1 
ATOM   6616 C CZ  . PHE F 6 152 ? 145.089 112.948 157.437 1.00 48.46  ? 143 PHE R CZ  1 
ATOM   6617 N N   . LEU F 6 153 ? 140.741 116.731 160.259 1.00 47.77  ? 144 LEU R N   1 
ATOM   6618 C CA  . LEU F 6 153 ? 139.584 117.172 159.488 1.00 47.77  ? 144 LEU R CA  1 
ATOM   6619 C C   . LEU F 6 153 ? 139.742 118.623 159.058 1.00 47.77  ? 144 LEU R C   1 
ATOM   6620 O O   . LEU F 6 153 ? 139.501 118.972 157.895 1.00 47.77  ? 144 LEU R O   1 
ATOM   6621 C CB  . LEU F 6 153 ? 138.312 117.003 160.320 1.00 47.77  ? 144 LEU R CB  1 
ATOM   6622 C CG  . LEU F 6 153 ? 137.493 115.726 160.128 1.00 47.77  ? 144 LEU R CG  1 
ATOM   6623 C CD1 . LEU F 6 153 ? 138.322 114.485 160.410 1.00 47.77  ? 144 LEU R CD1 1 
ATOM   6624 C CD2 . LEU F 6 153 ? 136.272 115.762 161.027 1.00 47.77  ? 144 LEU R CD2 1 
ATOM   6625 N N   . TYR F 6 154 ? 140.128 119.484 159.999 1.00 42.19  ? 145 TYR R N   1 
ATOM   6626 C CA  . TYR F 6 154 ? 140.308 120.898 159.697 1.00 42.19  ? 145 TYR R CA  1 
ATOM   6627 C C   . TYR F 6 154 ? 141.359 121.090 158.614 1.00 42.19  ? 145 TYR R C   1 
ATOM   6628 O O   . TYR F 6 154 ? 141.119 121.768 157.606 1.00 42.19  ? 145 TYR R O   1 
ATOM   6629 C CB  . TYR F 6 154 ? 140.701 121.641 160.974 1.00 42.19  ? 145 TYR R CB  1 
ATOM   6630 C CG  . TYR F 6 154 ? 140.948 123.115 160.788 1.00 42.19  ? 145 TYR R CG  1 
ATOM   6631 C CD1 . TYR F 6 154 ? 139.912 124.027 160.904 1.00 42.19  ? 145 TYR R CD1 1 
ATOM   6632 C CD2 . TYR F 6 154 ? 142.218 123.598 160.511 1.00 42.19  ? 145 TYR R CD2 1 
ATOM   6633 C CE1 . TYR F 6 154 ? 140.130 125.374 160.740 1.00 42.19  ? 145 TYR R CE1 1 
ATOM   6634 C CE2 . TYR F 6 154 ? 142.446 124.947 160.346 1.00 42.19  ? 145 TYR R CE2 1 
ATOM   6635 C CZ  . TYR F 6 154 ? 141.398 125.832 160.462 1.00 42.19  ? 145 TYR R CZ  1 
ATOM   6636 O OH  . TYR F 6 154 ? 141.617 127.180 160.299 1.00 42.19  ? 145 TYR R OH  1 
ATOM   6637 N N   . ILE F 6 155 ? 142.531 120.481 158.800 1.00 42.36  ? 146 ILE R N   1 
ATOM   6638 C CA  . ILE F 6 155 ? 143.615 120.642 157.838 1.00 42.36  ? 146 ILE R CA  1 
ATOM   6639 C C   . ILE F 6 155 ? 143.158 120.209 156.453 1.00 42.36  ? 146 ILE R C   1 
ATOM   6640 O O   . ILE F 6 155 ? 143.590 120.767 155.438 1.00 42.36  ? 146 ILE R O   1 
ATOM   6641 C CB  . ILE F 6 155 ? 144.856 119.854 158.295 1.00 42.36  ? 146 ILE R CB  1 
ATOM   6642 C CG1 . ILE F 6 155 ? 145.457 120.499 159.546 1.00 42.36  ? 146 ILE R CG1 1 
ATOM   6643 C CG2 . ILE F 6 155 ? 145.882 119.783 157.175 1.00 42.36  ? 146 ILE R CG2 1 
ATOM   6644 C CD1 . ILE F 6 155 ? 146.467 119.628 160.263 1.00 42.36  ? 146 ILE R CD1 1 
ATOM   6645 N N   . ILE F 6 156 ? 142.277 119.212 156.387 1.00 40.89  ? 147 ILE R N   1 
ATOM   6646 C CA  . ILE F 6 156 ? 141.807 118.738 155.088 1.00 40.89  ? 147 ILE R CA  1 
ATOM   6647 C C   . ILE F 6 156 ? 140.835 119.739 154.470 1.00 40.89  ? 147 ILE R C   1 
ATOM   6648 O O   . ILE F 6 156 ? 141.078 120.278 153.380 1.00 40.89  ? 147 ILE R O   1 
ATOM   6649 C CB  . ILE F 6 156 ? 141.166 117.346 155.217 1.00 40.89  ? 147 ILE R CB  1 
ATOM   6650 C CG1 . ILE F 6 156 ? 142.194 116.326 155.705 1.00 40.89  ? 147 ILE R CG1 1 
ATOM   6651 C CG2 . ILE F 6 156 ? 140.595 116.901 153.883 1.00 40.89  ? 147 ILE R CG2 1 
ATOM   6652 C CD1 . ILE F 6 156 ? 141.582 115.163 156.452 1.00 40.89  ? 147 ILE R CD1 1 
ATOM   6653 N N   . TYR F 6 157 ? 139.708 120.001 155.142 1.00 38.73  ? 148 TYR R N   1 
ATOM   6654 C CA  . TYR F 6 157 ? 138.666 120.712 154.412 1.00 38.73  ? 148 TYR R CA  1 
ATOM   6655 C C   . TYR F 6 157 ? 138.941 122.204 154.313 1.00 38.73  ? 148 TYR R C   1 
ATOM   6656 O O   . TYR F 6 157 ? 138.370 122.853 153.436 1.00 38.73  ? 148 TYR R O   1 
ATOM   6657 C CB  . TYR F 6 157 ? 137.255 120.530 154.992 1.00 38.73  ? 148 TYR R CB  1 
ATOM   6658 C CG  . TYR F 6 157 ? 136.980 121.071 156.372 1.00 38.73  ? 148 TYR R CG  1 
ATOM   6659 C CD1 . TYR F 6 157 ? 137.170 120.302 157.501 1.00 38.73  ? 148 TYR R CD1 1 
ATOM   6660 C CD2 . TYR F 6 157 ? 136.497 122.361 156.533 1.00 38.73  ? 148 TYR R CD2 1 
ATOM   6661 C CE1 . TYR F 6 157 ? 136.897 120.804 158.758 1.00 38.73  ? 148 TYR R CE1 1 
ATOM   6662 C CE2 . TYR F 6 157 ? 136.225 122.871 157.780 1.00 38.73  ? 148 TYR R CE2 1 
ATOM   6663 C CZ  . TYR F 6 157 ? 136.426 122.091 158.890 1.00 38.73  ? 148 TYR R CZ  1 
ATOM   6664 O OH  . TYR F 6 157 ? 136.154 122.600 160.138 1.00 38.73  ? 148 TYR R OH  1 
ATOM   6665 N N   . THR F 6 158 ? 139.806 122.777 155.157 1.00 36.75  ? 149 THR R N   1 
ATOM   6666 C CA  . THR F 6 158 ? 140.193 124.163 154.920 1.00 36.75  ? 149 THR R CA  1 
ATOM   6667 C C   . THR F 6 158 ? 140.892 124.296 153.574 1.00 36.75  ? 149 THR R C   1 
ATOM   6668 O O   . THR F 6 158 ? 140.567 125.187 152.778 1.00 36.75  ? 149 THR R O   1 
ATOM   6669 C CB  . THR F 6 158 ? 141.086 124.671 156.054 1.00 36.75  ? 149 THR R CB  1 
ATOM   6670 O OG1 . THR F 6 158 ? 141.301 126.080 155.901 1.00 36.75  ? 149 THR R OG1 1 
ATOM   6671 C CG2 . THR F 6 158 ? 142.431 123.955 156.066 1.00 36.75  ? 149 THR R CG2 1 
ATOM   6672 N N   . VAL F 6 159 ? 141.826 123.388 153.283 1.00 34.48  ? 150 VAL R N   1 
ATOM   6673 C CA  . VAL F 6 159 ? 142.492 123.388 151.986 1.00 34.48  ? 150 VAL R CA  1 
ATOM   6674 C C   . VAL F 6 159 ? 141.484 123.120 150.879 1.00 34.48  ? 150 VAL R C   1 
ATOM   6675 O O   . VAL F 6 159 ? 141.508 123.763 149.819 1.00 34.48  ? 150 VAL R O   1 
ATOM   6676 C CB  . VAL F 6 159 ? 143.630 122.348 151.983 1.00 34.48  ? 150 VAL R CB  1 
ATOM   6677 C CG1 . VAL F 6 159 ? 144.043 121.996 150.565 1.00 34.48  ? 150 VAL R CG1 1 
ATOM   6678 C CG2 . VAL F 6 159 ? 144.818 122.863 152.780 1.00 34.48  ? 150 VAL R CG2 1 
ATOM   6679 N N   . GLY F 6 160 ? 140.584 122.161 151.102 1.00 31.71  ? 151 GLY R N   1 
ATOM   6680 C CA  . GLY F 6 160 ? 139.593 121.860 150.081 1.00 31.71  ? 151 GLY R CA  1 
ATOM   6681 C C   . GLY F 6 160 ? 138.749 123.069 149.723 1.00 31.71  ? 151 GLY R C   1 
ATOM   6682 O O   . GLY F 6 160 ? 138.569 123.394 148.546 1.00 31.71  ? 151 GLY R O   1 
ATOM   6683 N N   . TYR F 6 161 ? 138.232 123.763 150.738 1.00 32.33  ? 152 TYR R N   1 
ATOM   6684 C CA  . TYR F 6 161 ? 137.402 124.937 150.497 1.00 32.33  ? 152 TYR R CA  1 
ATOM   6685 C C   . TYR F 6 161 ? 138.207 126.054 149.849 1.00 32.33  ? 152 TYR R C   1 
ATOM   6686 O O   . TYR F 6 161 ? 137.693 126.770 148.982 1.00 32.33  ? 152 TYR R O   1 
ATOM   6687 C CB  . TYR F 6 161 ? 136.782 125.420 151.809 1.00 32.33  ? 152 TYR R CB  1 
ATOM   6688 C CG  . TYR F 6 161 ? 135.413 124.846 152.110 1.00 32.33  ? 152 TYR R CG  1 
ATOM   6689 C CD1 . TYR F 6 161 ? 134.379 124.941 151.194 1.00 32.33  ? 152 TYR R CD1 1 
ATOM   6690 C CD2 . TYR F 6 161 ? 135.159 124.212 153.316 1.00 32.33  ? 152 TYR R CD2 1 
ATOM   6691 C CE1 . TYR F 6 161 ? 133.131 124.418 151.469 1.00 32.33  ? 152 TYR R CE1 1 
ATOM   6692 C CE2 . TYR F 6 161 ? 133.917 123.687 153.599 1.00 32.33  ? 152 TYR R CE2 1 
ATOM   6693 C CZ  . TYR F 6 161 ? 132.907 123.792 152.674 1.00 32.33  ? 152 TYR R CZ  1 
ATOM   6694 O OH  . TYR F 6 161 ? 131.668 123.270 152.955 1.00 32.33  ? 152 TYR R OH  1 
ATOM   6695 N N   . ALA F 6 162 ? 139.464 126.231 150.260 1.00 33.58  ? 153 ALA R N   1 
ATOM   6696 C CA  . ALA F 6 162 ? 140.287 127.271 149.653 1.00 33.58  ? 153 ALA R CA  1 
ATOM   6697 C C   . ALA F 6 162 ? 140.457 127.025 148.158 1.00 33.58  ? 153 ALA R C   1 
ATOM   6698 O O   . ALA F 6 162 ? 140.263 127.934 147.341 1.00 33.58  ? 153 ALA R O   1 
ATOM   6699 C CB  . ALA F 6 162 ? 141.645 127.335 150.352 1.00 33.58  ? 153 ALA R CB  1 
ATOM   6700 N N   . LEU F 6 163 ? 140.805 125.793 147.780 1.00 31.08  ? 154 LEU R N   1 
ATOM   6701 C CA  . LEU F 6 163 ? 140.951 125.481 146.360 1.00 31.08  ? 154 LEU R CA  1 
ATOM   6702 C C   . LEU F 6 163 ? 139.626 125.609 145.619 1.00 31.08  ? 154 LEU R C   1 
ATOM   6703 O O   . LEU F 6 163 ? 139.589 126.093 144.481 1.00 31.08  ? 154 LEU R O   1 
ATOM   6704 C CB  . LEU F 6 163 ? 141.536 124.080 146.174 1.00 31.08  ? 154 LEU R CB  1 
ATOM   6705 C CG  . LEU F 6 163 ? 143.060 123.942 146.262 1.00 31.08  ? 154 LEU R CG  1 
ATOM   6706 C CD1 . LEU F 6 163 ? 143.727 124.710 145.134 1.00 31.08  ? 154 LEU R CD1 1 
ATOM   6707 C CD2 . LEU F 6 163 ? 143.595 124.416 147.597 1.00 31.08  ? 154 LEU R CD2 1 
ATOM   6708 N N   . SER F 6 164 ? 138.526 125.175 146.239 1.00 28.62  ? 155 SER R N   1 
ATOM   6709 C CA  . SER F 6 164 ? 137.228 125.282 145.579 1.00 28.62  ? 155 SER R CA  1 
ATOM   6710 C C   . SER F 6 164 ? 136.871 126.735 145.299 1.00 28.62  ? 155 SER R C   1 
ATOM   6711 O O   . SER F 6 164 ? 136.417 127.072 144.200 1.00 28.62  ? 155 SER R O   1 
ATOM   6712 C CB  . SER F 6 164 ? 136.153 124.621 146.438 1.00 28.62  ? 155 SER R CB  1 
ATOM   6713 O OG  . SER F 6 164 ? 136.504 123.284 146.744 1.00 28.62  ? 155 SER R OG  1 
ATOM   6714 N N   . PHE F 6 165 ? 137.074 127.613 146.281 1.00 29.31  ? 156 PHE R N   1 
ATOM   6715 C CA  . PHE F 6 165 ? 136.805 129.034 146.086 1.00 29.31  ? 156 PHE R CA  1 
ATOM   6716 C C   . PHE F 6 165 ? 137.714 129.623 145.013 1.00 29.31  ? 156 PHE R C   1 
ATOM   6717 O O   . PHE F 6 165 ? 137.263 130.395 144.151 1.00 29.31  ? 156 PHE R O   1 
ATOM   6718 C CB  . PHE F 6 165 ? 136.978 129.757 147.423 1.00 29.31  ? 156 PHE R CB  1 
ATOM   6719 C CG  . PHE F 6 165 ? 137.072 131.249 147.315 1.00 29.31  ? 156 PHE R CG  1 
ATOM   6720 C CD1 . PHE F 6 165 ? 138.297 131.869 147.139 1.00 29.31  ? 156 PHE R CD1 1 
ATOM   6721 C CD2 . PHE F 6 165 ? 135.940 132.034 147.418 1.00 29.31  ? 156 PHE R CD2 1 
ATOM   6722 C CE1 . PHE F 6 165 ? 138.386 133.242 147.050 1.00 29.31  ? 156 PHE R CE1 1 
ATOM   6723 C CE2 . PHE F 6 165 ? 136.023 133.407 147.332 1.00 29.31  ? 156 PHE R CE2 1 
ATOM   6724 C CZ  . PHE F 6 165 ? 137.247 134.012 147.148 1.00 29.31  ? 156 PHE R CZ  1 
ATOM   6725 N N   . SER F 6 166 ? 139.000 129.260 145.042 1.00 32.01  ? 157 SER R N   1 
ATOM   6726 C CA  . SER F 6 166 ? 139.941 129.779 144.056 1.00 32.01  ? 157 SER R CA  1 
ATOM   6727 C C   . SER F 6 166 ? 139.542 129.374 142.644 1.00 32.01  ? 157 SER R C   1 
ATOM   6728 O O   . SER F 6 166 ? 139.667 130.166 141.704 1.00 32.01  ? 157 SER R O   1 
ATOM   6729 C CB  . SER F 6 166 ? 141.352 129.286 144.373 1.00 32.01  ? 157 SER R CB  1 
ATOM   6730 O OG  . SER F 6 166 ? 142.222 129.500 143.277 1.00 32.01  ? 157 SER R OG  1 
ATOM   6731 N N   . ALA F 6 167 ? 139.083 128.136 142.470 1.00 29.18  ? 158 ALA R N   1 
ATOM   6732 C CA  . ALA F 6 167 ? 138.666 127.693 141.144 1.00 29.18  ? 158 ALA R CA  1 
ATOM   6733 C C   . ALA F 6 167 ? 137.351 128.341 140.733 1.00 29.18  ? 158 ALA R C   1 
ATOM   6734 O O   . ALA F 6 167 ? 137.171 128.712 139.567 1.00 29.18  ? 158 ALA R O   1 
ATOM   6735 C CB  . ALA F 6 167 ? 138.545 126.172 141.113 1.00 29.18  ? 158 ALA R CB  1 
ATOM   6736 N N   . LEU F 6 168 ? 136.415 128.481 141.676 1.00 26.49  ? 159 LEU R N   1 
ATOM   6737 C CA  . LEU F 6 168 ? 135.101 129.016 141.342 1.00 26.49  ? 159 LEU R CA  1 
ATOM   6738 C C   . LEU F 6 168 ? 135.184 130.469 140.902 1.00 26.49  ? 159 LEU R C   1 
ATOM   6739 O O   . LEU F 6 168 ? 134.475 130.879 139.976 1.00 26.49  ? 159 LEU R O   1 
ATOM   6740 C CB  . LEU F 6 168 ? 134.159 128.876 142.537 1.00 26.49  ? 159 LEU R CB  1 
ATOM   6741 C CG  . LEU F 6 168 ? 133.344 127.585 142.567 1.00 26.49  ? 159 LEU R CG  1 
ATOM   6742 C CD1 . LEU F 6 168 ? 132.781 127.346 143.954 1.00 26.49  ? 159 LEU R CD1 1 
ATOM   6743 C CD2 . LEU F 6 168 ? 132.232 127.636 141.536 1.00 26.49  ? 159 LEU R CD2 1 
ATOM   6744 N N   . VAL F 6 169 ? 136.025 131.273 141.555 1.00 31.07  ? 160 VAL R N   1 
ATOM   6745 C CA  . VAL F 6 169 ? 136.127 132.677 141.158 1.00 31.07  ? 160 VAL R CA  1 
ATOM   6746 C C   . VAL F 6 169 ? 136.605 132.783 139.712 1.00 31.07  ? 160 VAL R C   1 
ATOM   6747 O O   . VAL F 6 169 ? 136.047 133.539 138.905 1.00 31.07  ? 160 VAL R O   1 
ATOM   6748 C CB  . VAL F 6 169 ? 137.040 133.453 142.125 1.00 31.07  ? 160 VAL R CB  1 
ATOM   6749 C CG1 . VAL F 6 169 ? 138.448 132.885 142.133 1.00 31.07  ? 160 VAL R CG1 1 
ATOM   6750 C CG2 . VAL F 6 169 ? 137.062 134.929 141.762 1.00 31.07  ? 160 VAL R CG2 1 
ATOM   6751 N N   . ILE F 6 170 ? 137.629 132.004 139.354 1.00 33.33  ? 161 ILE R N   1 
ATOM   6752 C CA  . ILE F 6 170 ? 138.150 132.037 137.989 1.00 33.33  ? 161 ILE R CA  1 
ATOM   6753 C C   . ILE F 6 170 ? 137.101 131.538 137.005 1.00 33.33  ? 161 ILE R C   1 
ATOM   6754 O O   . ILE F 6 170 ? 136.941 132.093 135.910 1.00 33.33  ? 161 ILE R O   1 
ATOM   6755 C CB  . ILE F 6 170 ? 139.449 131.216 137.893 1.00 33.33  ? 161 ILE R CB  1 
ATOM   6756 C CG1 . ILE F 6 170 ? 140.613 131.999 138.501 1.00 33.33  ? 161 ILE R CG1 1 
ATOM   6757 C CG2 . ILE F 6 170 ? 139.749 130.857 136.443 1.00 33.33  ? 161 ILE R CG2 1 
ATOM   6758 C CD1 . ILE F 6 170 ? 141.865 131.175 138.715 1.00 33.33  ? 161 ILE R CD1 1 
ATOM   6759 N N   . ALA F 6 171 ? 136.389 130.467 137.362 1.00 31.89  ? 162 ALA R N   1 
ATOM   6760 C CA  . ALA F 6 171 ? 135.373 129.936 136.460 1.00 31.89  ? 162 ALA R CA  1 
ATOM   6761 C C   . ALA F 6 171 ? 134.277 130.961 136.202 1.00 31.89  ? 162 ALA R C   1 
ATOM   6762 O O   . ALA F 6 171 ? 133.840 131.143 135.060 1.00 31.89  ? 162 ALA R O   1 
ATOM   6763 C CB  . ALA F 6 171 ? 134.779 128.652 137.039 1.00 31.89  ? 162 ALA R CB  1 
ATOM   6764 N N   . SER F 6 172 ? 133.819 131.641 137.255 1.00 31.91  ? 163 SER R N   1 
ATOM   6765 C CA  . SER F 6 172 ? 132.801 132.670 137.080 1.00 31.91  ? 163 SER R CA  1 
ATOM   6766 C C   . SER F 6 172 ? 133.324 133.809 136.219 1.00 31.91  ? 163 SER R C   1 
ATOM   6767 O O   . SER F 6 172 ? 132.601 134.338 135.365 1.00 31.91  ? 163 SER R O   1 
ATOM   6768 C CB  . SER F 6 172 ? 132.344 133.192 138.440 1.00 31.91  ? 163 SER R CB  1 
ATOM   6769 O OG  . SER F 6 172 ? 131.319 134.159 138.295 1.00 31.91  ? 163 SER R OG  1 
ATOM   6770 N N   . ALA F 6 173 ? 134.580 134.209 136.434 1.00 35.92  ? 164 ALA R N   1 
ATOM   6771 C CA  . ALA F 6 173 ? 135.158 135.267 135.615 1.00 35.92  ? 164 ALA R CA  1 
ATOM   6772 C C   . ALA F 6 173 ? 135.160 134.872 134.144 1.00 35.92  ? 164 ALA R C   1 
ATOM   6773 O O   . ALA F 6 173 ? 134.793 135.668 133.273 1.00 35.92  ? 164 ALA R O   1 
ATOM   6774 C CB  . ALA F 6 173 ? 136.574 135.582 136.093 1.00 35.92  ? 164 ALA R CB  1 
ATOM   6775 N N   . ILE F 6 174 ? 135.563 133.635 133.848 1.00 39.30  ? 165 ILE R N   1 
ATOM   6776 C CA  . ILE F 6 174 ? 135.604 133.189 132.457 1.00 39.30  ? 165 ILE R CA  1 
ATOM   6777 C C   . ILE F 6 174 ? 134.200 133.146 131.869 1.00 39.30  ? 165 ILE R C   1 
ATOM   6778 O O   . ILE F 6 174 ? 133.982 133.551 130.721 1.00 39.30  ? 165 ILE R O   1 
ATOM   6779 C CB  . ILE F 6 174 ? 136.309 131.824 132.348 1.00 39.30  ? 165 ILE R CB  1 
ATOM   6780 C CG1 . ILE F 6 174 ? 137.825 132.019 132.331 1.00 39.30  ? 165 ILE R CG1 1 
ATOM   6781 C CG2 . ILE F 6 174 ? 135.856 131.087 131.091 1.00 39.30  ? 165 ILE R CG2 1 
ATOM   6782 C CD1 . ILE F 6 174 ? 138.619 130.741 132.501 1.00 39.30  ? 165 ILE R CD1 1 
ATOM   6783 N N   . LEU F 6 175 ? 133.225 132.649 132.635 1.00 36.22  ? 166 LEU R N   1 
ATOM   6784 C CA  . LEU F 6 175 ? 131.857 132.590 132.123 1.00 36.22  ? 166 LEU R CA  1 
ATOM   6785 C C   . LEU F 6 175 ? 131.329 133.982 131.804 1.00 36.22  ? 166 LEU R C   1 
ATOM   6786 O O   . LEU F 6 175 ? 130.682 134.186 130.771 1.00 36.22  ? 166 LEU R O   1 
ATOM   6787 C CB  . LEU F 6 175 ? 130.934 131.895 133.123 1.00 36.22  ? 166 LEU R CB  1 
ATOM   6788 C CG  . LEU F 6 175 ? 131.134 130.395 133.327 1.00 36.22  ? 166 LEU R CG  1 
ATOM   6789 C CD1 . LEU F 6 175 ? 130.225 129.891 134.433 1.00 36.22  ? 166 LEU R CD1 1 
ATOM   6790 C CD2 . LEU F 6 175 ? 130.878 129.636 132.037 1.00 36.22  ? 166 LEU R CD2 1 
ATOM   6791 N N   . LEU F 6 176 ? 131.587 134.952 132.681 1.00 36.23  ? 167 LEU R N   1 
ATOM   6792 C CA  . LEU F 6 176 ? 131.124 136.309 132.428 1.00 36.23  ? 167 LEU R CA  1 
ATOM   6793 C C   . LEU F 6 176 ? 131.939 137.016 131.354 1.00 36.23  ? 167 LEU R C   1 
ATOM   6794 O O   . LEU F 6 176 ? 131.469 138.014 130.797 1.00 36.23  ? 167 LEU R O   1 
ATOM   6795 C CB  . LEU F 6 176 ? 131.158 137.127 133.719 1.00 36.23  ? 167 LEU R CB  1 
ATOM   6796 C CG  . LEU F 6 176 ? 129.863 137.093 134.531 1.00 36.23  ? 167 LEU R CG  1 
ATOM   6797 C CD1 . LEU F 6 176 ? 130.108 137.574 135.949 1.00 36.23  ? 167 LEU R CD1 1 
ATOM   6798 C CD2 . LEU F 6 176 ? 128.788 137.929 133.857 1.00 36.23  ? 167 LEU R CD2 1 
ATOM   6799 N N   . GLY F 6 177 ? 133.139 136.527 131.050 1.00 44.60  ? 168 GLY R N   1 
ATOM   6800 C CA  . GLY F 6 177 ? 133.973 137.150 130.043 1.00 44.60  ? 168 GLY R CA  1 
ATOM   6801 C C   . GLY F 6 177 ? 133.343 137.157 128.667 1.00 44.60  ? 168 GLY R C   1 
ATOM   6802 O O   . GLY F 6 177 ? 132.996 138.220 128.142 1.00 44.60  ? 168 GLY R O   1 
ATOM   6803 N N   . PHE F 6 178 ? 133.184 135.979 128.072 1.00 46.61  ? 169 PHE R N   1 
ATOM   6804 C CA  . PHE F 6 178 ? 132.603 135.887 126.740 1.00 46.61  ? 169 PHE R CA  1 
ATOM   6805 C C   . PHE F 6 178 ? 131.097 136.103 126.810 1.00 46.61  ? 169 PHE R C   1 
ATOM   6806 O O   . PHE F 6 178 ? 130.406 135.467 127.611 1.00 46.61  ? 169 PHE R O   1 
ATOM   6807 C CB  . PHE F 6 178 ? 132.911 134.527 126.117 1.00 46.61  ? 169 PHE R CB  1 
ATOM   6808 C CG  . PHE F 6 178 ? 134.380 134.236 125.972 1.00 46.61  ? 169 PHE R CG  1 
ATOM   6809 C CD1 . PHE F 6 178 ? 135.148 133.898 127.072 1.00 46.61  ? 169 PHE R CD1 1 
ATOM   6810 C CD2 . PHE F 6 178 ? 134.989 134.293 124.732 1.00 46.61  ? 169 PHE R CD2 1 
ATOM   6811 C CE1 . PHE F 6 178 ? 136.495 133.629 126.939 1.00 46.61  ? 169 PHE R CE1 1 
ATOM   6812 C CE2 . PHE F 6 178 ? 136.337 134.023 124.594 1.00 46.61  ? 169 PHE R CE2 1 
ATOM   6813 C CZ  . PHE F 6 178 ? 137.089 133.691 125.698 1.00 46.61  ? 169 PHE R CZ  1 
ATOM   6814 N N   . ARG F 6 179 ? 130.587 137.005 125.970 1.00 47.50  ? 170 ARG R N   1 
ATOM   6815 C CA  . ARG F 6 179 ? 129.149 137.231 125.901 1.00 47.50  ? 170 ARG R CA  1 
ATOM   6816 C C   . ARG F 6 179 ? 128.435 136.180 125.062 1.00 47.50  ? 170 ARG R C   1 
ATOM   6817 O O   . ARG F 6 179 ? 127.208 136.067 125.146 1.00 47.50  ? 170 ARG R O   1 
ATOM   6818 C CB  . ARG F 6 179 ? 128.859 138.622 125.335 1.00 47.50  ? 170 ARG R CB  1 
ATOM   6819 C CG  . ARG F 6 179 ? 127.408 139.052 125.470 1.00 47.50  ? 170 ARG R CG  1 
ATOM   6820 C CD  . ARG F 6 179 ? 127.176 140.425 124.869 1.00 47.50  ? 170 ARG R CD  1 
ATOM   6821 N NE  . ARG F 6 179 ? 127.459 141.495 125.818 1.00 47.50  ? 170 ARG R NE  1 
ATOM   6822 C CZ  . ARG F 6 179 ? 126.556 142.069 126.602 1.00 47.50  ? 170 ARG R CZ  1 
ATOM   6823 N NH1 . ARG F 6 179 ? 125.288 141.689 126.593 1.00 47.50  ? 170 ARG R NH1 1 
ATOM   6824 N NH2 . ARG F 6 179 ? 126.935 143.049 127.418 1.00 47.50  ? 170 ARG R NH2 1 
ATOM   6825 N N   . HIS F 6 180 ? 129.175 135.409 124.264 1.00 46.04  ? 171 HIS R N   1 
ATOM   6826 C CA  . HIS F 6 180 ? 128.556 134.364 123.458 1.00 46.04  ? 171 HIS R CA  1 
ATOM   6827 C C   . HIS F 6 180 ? 127.880 133.326 124.345 1.00 46.04  ? 171 HIS R C   1 
ATOM   6828 O O   . HIS F 6 180 ? 126.780 132.852 124.038 1.00 46.04  ? 171 HIS R O   1 
ATOM   6829 C CB  . HIS F 6 180 ? 129.619 133.715 122.568 1.00 46.04  ? 171 HIS R CB  1 
ATOM   6830 C CG  . HIS F 6 180 ? 129.092 132.662 121.640 1.00 46.04  ? 171 HIS R CG  1 
ATOM   6831 N ND1 . HIS F 6 180 ? 127.770 132.270 121.645 1.00 46.04  ? 171 HIS R ND1 1 
ATOM   6832 C CD2 . HIS F 6 180 ? 129.704 131.903 120.701 1.00 46.04  ? 171 HIS R CD2 1 
ATOM   6833 C CE1 . HIS F 6 180 ? 127.588 131.329 120.736 1.00 46.04  ? 171 HIS R CE1 1 
ATOM   6834 N NE2 . HIS F 6 180 ? 128.746 131.087 120.150 1.00 46.04  ? 171 HIS R NE2 1 
ATOM   6835 N N   . LEU F 6 181 ? 128.514 132.977 125.463 1.00 43.28  ? 172 LEU R N   1 
ATOM   6836 C CA  . LEU F 6 181 ? 128.034 131.892 126.309 1.00 43.28  ? 172 LEU R CA  1 
ATOM   6837 C C   . LEU F 6 181 ? 126.752 132.234 127.057 1.00 43.28  ? 172 LEU R C   1 
ATOM   6838 O O   . LEU F 6 181 ? 126.160 131.336 127.662 1.00 43.28  ? 172 LEU R O   1 
ATOM   6839 C CB  . LEU F 6 181 ? 129.121 131.502 127.313 1.00 43.28  ? 172 LEU R CB  1 
ATOM   6840 C CG  . LEU F 6 181 ? 130.540 131.367 126.753 1.00 43.28  ? 172 LEU R CG  1 
ATOM   6841 C CD1 . LEU F 6 181 ? 131.516 130.995 127.854 1.00 43.28  ? 172 LEU R CD1 1 
ATOM   6842 C CD2 . LEU F 6 181 ? 130.589 130.346 125.630 1.00 43.28  ? 172 LEU R CD2 1 
ATOM   6843 N N   . HIS F 6 182 ? 126.308 133.488 127.031 1.00 40.00  ? 173 HIS R N   1 
ATOM   6844 C CA  . HIS F 6 182 ? 125.154 133.888 127.829 1.00 40.00  ? 173 HIS R CA  1 
ATOM   6845 C C   . HIS F 6 182 ? 123.923 133.062 127.474 1.00 40.00  ? 173 HIS R C   1 
ATOM   6846 O O   . HIS F 6 182 ? 123.599 132.876 126.298 1.00 40.00  ? 173 HIS R O   1 
ATOM   6847 C CB  . HIS F 6 182 ? 124.862 135.372 127.620 1.00 40.00  ? 173 HIS R CB  1 
ATOM   6848 C CG  . HIS F 6 182 ? 125.691 136.277 128.475 1.00 40.00  ? 173 HIS R CG  1 
ATOM   6849 N ND1 . HIS F 6 182 ? 127.069 136.280 128.437 1.00 40.00  ? 173 HIS R ND1 1 
ATOM   6850 C CD2 . HIS F 6 182 ? 125.337 137.210 129.391 1.00 40.00  ? 173 HIS R CD2 1 
ATOM   6851 C CE1 . HIS F 6 182 ? 127.528 137.176 129.293 1.00 40.00  ? 173 HIS R CE1 1 
ATOM   6852 N NE2 . HIS F 6 182 ? 126.498 137.754 129.884 1.00 40.00  ? 173 HIS R NE2 1 
ATOM   6853 N N   . CYS F 6 183 ? 123.235 132.572 128.506 1.00 31.23  ? 174 CYS R N   1 
ATOM   6854 C CA  . CYS F 6 183 ? 121.976 131.854 128.348 1.00 31.23  ? 174 CYS R CA  1 
ATOM   6855 C C   . CYS F 6 183 ? 121.391 131.548 129.721 1.00 31.23  ? 174 CYS R C   1 
ATOM   6856 O O   . CYS F 6 183 ? 122.013 131.854 130.743 1.00 31.23  ? 174 CYS R O   1 
ATOM   6857 C CB  . CYS F 6 183 ? 122.174 130.563 127.553 1.00 31.23  ? 174 CYS R CB  1 
ATOM   6858 S SG  . CYS F 6 183 ? 123.296 129.379 128.320 1.00 31.23  ? 174 CYS R SG  1 
ATOM   6859 N N   . THR F 6 184 ? 120.198 130.950 129.761 1.00 26.22  ? 175 THR R N   1 
ATOM   6860 C CA  . THR F 6 184 ? 119.588 130.620 131.045 1.00 26.22  ? 175 THR R CA  1 
ATOM   6861 C C   . THR F 6 184 ? 120.433 129.613 131.814 1.00 26.22  ? 175 THR R C   1 
ATOM   6862 O O   . THR F 6 184 ? 120.630 129.750 133.030 1.00 26.22  ? 175 THR R O   1 
ATOM   6863 C CB  . THR F 6 184 ? 118.178 130.072 130.828 1.00 26.22  ? 175 THR R CB  1 
ATOM   6864 O OG1 . THR F 6 184 ? 117.450 130.953 129.964 1.00 26.22  ? 175 THR R OG1 1 
ATOM   6865 C CG2 . THR F 6 184 ? 117.443 129.945 132.150 1.00 26.22  ? 175 THR R CG2 1 
ATOM   6866 N N   . ARG F 6 185 ? 120.943 128.595 131.120 1.00 26.53  ? 176 ARG R N   1 
ATOM   6867 C CA  . ARG F 6 185 ? 121.773 127.587 131.767 1.00 26.53  ? 176 ARG R CA  1 
ATOM   6868 C C   . ARG F 6 185 ? 122.950 128.228 132.489 1.00 26.53  ? 176 ARG R C   1 
ATOM   6869 O O   . ARG F 6 185 ? 123.224 127.926 133.657 1.00 26.53  ? 176 ARG R O   1 
ATOM   6870 C CB  . ARG F 6 185 ? 122.260 126.585 130.720 1.00 26.53  ? 176 ARG R CB  1 
ATOM   6871 C CG  . ARG F 6 185 ? 123.069 125.432 131.274 1.00 26.53  ? 176 ARG R CG  1 
ATOM   6872 C CD  . ARG F 6 185 ? 123.275 124.351 130.227 1.00 26.53  ? 176 ARG R CD  1 
ATOM   6873 N NE  . ARG F 6 185 ? 124.618 124.378 129.658 1.00 26.53  ? 176 ARG R NE  1 
ATOM   6874 C CZ  . ARG F 6 185 ? 124.962 125.048 128.568 1.00 26.53  ? 176 ARG R CZ  1 
ATOM   6875 N NH1 . ARG F 6 185 ? 124.089 125.787 127.903 1.00 26.53  ? 176 ARG R NH1 1 
ATOM   6876 N NH2 . ARG F 6 185 ? 126.216 124.976 128.132 1.00 26.53  ? 176 ARG R NH2 1 
ATOM   6877 N N   . ASN F 6 186 ? 123.656 129.128 131.807 1.00 29.29  ? 177 ASN R N   1 
ATOM   6878 C CA  . ASN F 6 186 ? 124.820 129.752 132.420 1.00 29.29  ? 177 ASN R CA  1 
ATOM   6879 C C   . ASN F 6 186 ? 124.426 130.689 133.554 1.00 29.29  ? 177 ASN R C   1 
ATOM   6880 O O   . ASN F 6 186 ? 125.183 130.838 134.514 1.00 29.29  ? 177 ASN R O   1 
ATOM   6881 C CB  . ASN F 6 186 ? 125.635 130.491 131.363 1.00 29.29  ? 177 ASN R CB  1 
ATOM   6882 C CG  . ASN F 6 186 ? 126.599 129.576 130.634 1.00 29.29  ? 177 ASN R CG  1 
ATOM   6883 O OD1 . ASN F 6 186 ? 127.178 128.667 131.227 1.00 29.29  ? 177 ASN R OD1 1 
ATOM   6884 N ND2 . ASN F 6 186 ? 126.776 129.811 129.343 1.00 29.29  ? 177 ASN R ND2 1 
ATOM   6885 N N   . TYR F 6 187 ? 123.256 131.325 133.473 1.00 29.35  ? 178 TYR R N   1 
ATOM   6886 C CA  . TYR F 6 187 ? 122.799 132.139 134.595 1.00 29.35  ? 178 TYR R CA  1 
ATOM   6887 C C   . TYR F 6 187 ? 122.569 131.282 135.833 1.00 29.35  ? 178 TYR R C   1 
ATOM   6888 O O   . TYR F 6 187 ? 122.970 131.654 136.947 1.00 29.35  ? 178 TYR R O   1 
ATOM   6889 C CB  . TYR F 6 187 ? 121.519 132.883 134.215 1.00 29.35  ? 178 TYR R CB  1 
ATOM   6890 C CG  . TYR F 6 187 ? 121.654 133.754 132.987 1.00 29.35  ? 178 TYR R CG  1 
ATOM   6891 C CD1 . TYR F 6 187 ? 122.882 134.282 132.613 1.00 29.35  ? 178 TYR R CD1 1 
ATOM   6892 C CD2 . TYR F 6 187 ? 120.551 134.045 132.198 1.00 29.35  ? 178 TYR R CD2 1 
ATOM   6893 C CE1 . TYR F 6 187 ? 123.006 135.076 131.492 1.00 29.35  ? 178 TYR R CE1 1 
ATOM   6894 C CE2 . TYR F 6 187 ? 120.667 134.838 131.074 1.00 29.35  ? 178 TYR R CE2 1 
ATOM   6895 C CZ  . TYR F 6 187 ? 121.896 135.351 130.725 1.00 29.35  ? 178 TYR R CZ  1 
ATOM   6896 O OH  . TYR F 6 187 ? 122.016 136.141 129.606 1.00 29.35  ? 178 TYR R OH  1 
ATOM   6897 N N   . ILE F 6 188 ? 121.930 130.125 135.656 1.00 22.94  ? 179 ILE R N   1 
ATOM   6898 C CA  . ILE F 6 188 ? 121.716 129.223 136.783 1.00 22.94  ? 179 ILE R CA  1 
ATOM   6899 C C   . ILE F 6 188 ? 123.057 128.750 137.335 1.00 22.94  ? 179 ILE R C   1 
ATOM   6900 O O   . ILE F 6 188 ? 123.255 128.665 138.556 1.00 22.94  ? 179 ILE R O   1 
ATOM   6901 C CB  . ILE F 6 188 ? 120.825 128.042 136.348 1.00 22.94  ? 179 ILE R CB  1 
ATOM   6902 C CG1 . ILE F 6 188 ? 119.492 128.534 135.777 1.00 22.94  ? 179 ILE R CG1 1 
ATOM   6903 C CG2 . ILE F 6 188 ? 120.531 127.143 137.516 1.00 22.94  ? 179 ILE R CG2 1 
ATOM   6904 C CD1 . ILE F 6 188 ? 118.643 129.321 136.750 1.00 22.94  ? 179 ILE R CD1 1 
ATOM   6905 N N   . HIS F 6 189 ? 124.008 128.459 136.443 1.00 24.07  ? 180 HIS R N   1 
ATOM   6906 C CA  . HIS F 6 189 ? 125.339 128.060 136.890 1.00 24.07  ? 180 HIS R CA  1 
ATOM   6907 C C   . HIS F 6 189 ? 126.006 129.165 137.700 1.00 24.07  ? 180 HIS R C   1 
ATOM   6908 O O   . HIS F 6 189 ? 126.667 128.894 138.710 1.00 24.07  ? 180 HIS R O   1 
ATOM   6909 C CB  . HIS F 6 189 ? 126.210 127.691 135.691 1.00 24.07  ? 180 HIS R CB  1 
ATOM   6910 C CG  . HIS F 6 189 ? 125.813 126.415 135.021 1.00 24.07  ? 180 HIS R CG  1 
ATOM   6911 N ND1 . HIS F 6 189 ? 125.179 125.389 135.689 1.00 24.07  ? 180 HIS R ND1 1 
ATOM   6912 C CD2 . HIS F 6 189 ? 125.974 125.991 133.746 1.00 24.07  ? 180 HIS R CD2 1 
ATOM   6913 C CE1 . HIS F 6 189 ? 124.956 124.394 134.851 1.00 24.07  ? 180 HIS R CE1 1 
ATOM   6914 N NE2 . HIS F 6 189 ? 125.430 124.732 133.666 1.00 24.07  ? 180 HIS R NE2 1 
ATOM   6915 N N   . LEU F 6 190 ? 125.870 130.414 137.256 1.00 26.27  ? 181 LEU R N   1 
ATOM   6916 C CA  . LEU F 6 190 ? 126.477 131.527 137.977 1.00 26.27  ? 181 LEU R CA  1 
ATOM   6917 C C   . LEU F 6 190 ? 125.872 131.672 139.364 1.00 26.27  ? 181 LEU R C   1 
ATOM   6918 O O   . LEU F 6 190 ? 126.586 131.933 140.340 1.00 26.27  ? 181 LEU R O   1 
ATOM   6919 C CB  . LEU F 6 190 ? 126.308 132.820 137.182 1.00 26.27  ? 181 LEU R CB  1 
ATOM   6920 C CG  . LEU F 6 190 ? 127.135 132.932 135.901 1.00 26.27  ? 181 LEU R CG  1 
ATOM   6921 C CD1 . LEU F 6 190 ? 126.699 134.142 135.094 1.00 26.27  ? 181 LEU R CD1 1 
ATOM   6922 C CD2 . LEU F 6 190 ? 128.619 133.008 136.216 1.00 26.27  ? 181 LEU R CD2 1 
ATOM   6923 N N   . ASN F 6 191 ? 124.554 131.512 139.473 1.00 22.27  ? 182 ASN R N   1 
ATOM   6924 C CA  . ASN F 6 191 ? 123.936 131.550 140.794 1.00 22.27  ? 182 ASN R CA  1 
ATOM   6925 C C   . ASN F 6 191 ? 124.483 130.438 141.682 1.00 22.27  ? 182 ASN R C   1 
ATOM   6926 O O   . ASN F 6 191 ? 124.749 130.651 142.873 1.00 22.27  ? 182 ASN R O   1 
ATOM   6927 C CB  . ASN F 6 191 ? 122.418 131.448 140.669 1.00 22.27  ? 182 ASN R CB  1 
ATOM   6928 C CG  . ASN F 6 191 ? 121.767 132.784 140.365 1.00 22.27  ? 182 ASN R CG  1 
ATOM   6929 O OD1 . ASN F 6 191 ? 122.131 133.807 140.940 1.00 22.27  ? 182 ASN R OD1 1 
ATOM   6930 N ND2 . ASN F 6 191 ? 120.801 132.780 139.458 1.00 22.27  ? 182 ASN R ND2 1 
ATOM   6931 N N   . LEU F 6 192 ? 124.664 129.241 141.118 1.00 20.18  ? 183 LEU R N   1 
ATOM   6932 C CA  . LEU F 6 192 ? 125.240 128.145 141.894 1.00 20.18  ? 183 LEU R CA  1 
ATOM   6933 C C   . LEU F 6 192 ? 126.643 128.490 142.380 1.00 20.18  ? 183 LEU R C   1 
ATOM   6934 O O   . LEU F 6 192 ? 126.996 128.229 143.539 1.00 20.18  ? 183 LEU R O   1 
ATOM   6935 C CB  . LEU F 6 192 ? 125.267 126.874 141.050 1.00 20.18  ? 183 LEU R CB  1 
ATOM   6936 C CG  . LEU F 6 192 ? 125.693 125.597 141.772 1.00 20.18  ? 183 LEU R CG  1 
ATOM   6937 C CD1 . LEU F 6 192 ? 124.617 125.151 142.745 1.00 20.18  ? 183 LEU R CD1 1 
ATOM   6938 C CD2 . LEU F 6 192 ? 126.000 124.504 140.764 1.00 20.18  ? 183 LEU R CD2 1 
ATOM   6939 N N   . PHE F 6 193 ? 127.462 129.068 141.500 1.00 22.89  ? 184 PHE R N   1 
ATOM   6940 C CA  . PHE F 6 193 ? 128.817 129.450 141.887 1.00 22.89  ? 184 PHE R CA  1 
ATOM   6941 C C   . PHE F 6 193 ? 128.791 130.474 143.014 1.00 22.89  ? 184 PHE R C   1 
ATOM   6942 O O   . PHE F 6 193 ? 129.588 130.398 143.958 1.00 22.89  ? 184 PHE R O   1 
ATOM   6943 C CB  . PHE F 6 193 ? 129.574 130.016 140.684 1.00 22.89  ? 184 PHE R CB  1 
ATOM   6944 C CG  . PHE F 6 193 ? 129.797 129.028 139.570 1.00 22.89  ? 184 PHE R CG  1 
ATOM   6945 C CD1 . PHE F 6 193 ? 129.326 127.729 139.651 1.00 22.89  ? 184 PHE R CD1 1 
ATOM   6946 C CD2 . PHE F 6 193 ? 130.487 129.410 138.434 1.00 22.89  ? 184 PHE R CD2 1 
ATOM   6947 C CE1 . PHE F 6 193 ? 129.540 126.837 138.622 1.00 22.89  ? 184 PHE R CE1 1 
ATOM   6948 C CE2 . PHE F 6 193 ? 130.702 128.520 137.405 1.00 22.89  ? 184 PHE R CE2 1 
ATOM   6949 C CZ  . PHE F 6 193 ? 130.229 127.234 137.499 1.00 22.89  ? 184 PHE R CZ  1 
ATOM   6950 N N   . ALA F 6 194 ? 127.886 131.449 142.923 1.00 20.35  ? 185 ALA R N   1 
ATOM   6951 C CA  . ALA F 6 194 ? 127.771 132.444 143.981 1.00 20.35  ? 185 ALA R CA  1 
ATOM   6952 C C   . ALA F 6 194 ? 127.403 131.791 145.306 1.00 20.35  ? 185 ALA R C   1 
ATOM   6953 O O   . ALA F 6 194 ? 127.955 132.142 146.356 1.00 20.35  ? 185 ALA R O   1 
ATOM   6954 C CB  . ALA F 6 194 ? 126.735 133.498 143.600 1.00 20.35  ? 185 ALA R CB  1 
ATOM   6955 N N   . SER F 6 195 ? 126.469 130.838 145.278 1.00 20.38  ? 186 SER R N   1 
ATOM   6956 C CA  . SER F 6 195 ? 126.086 130.154 146.510 1.00 20.38  ? 186 SER R CA  1 
ATOM   6957 C C   . SER F 6 195 ? 127.274 129.414 147.115 1.00 20.38  ? 186 SER R C   1 
ATOM   6958 O O   . SER F 6 195 ? 127.505 129.471 148.330 1.00 20.38  ? 186 SER R O   1 
ATOM   6959 C CB  . SER F 6 195 ? 124.935 129.190 146.237 1.00 20.38  ? 186 SER R CB  1 
ATOM   6960 O OG  . SER F 6 195 ? 125.377 128.077 145.483 1.00 20.38  ? 186 SER R OG  1 
ATOM   6961 N N   . PHE F 6 196 ? 128.046 128.716 146.278 1.00 21.01  ? 187 PHE R N   1 
ATOM   6962 C CA  . PHE F 6 196 ? 129.217 128.006 146.789 1.00 21.01  ? 187 PHE R CA  1 
ATOM   6963 C C   . PHE F 6 196 ? 130.220 128.970 147.411 1.00 21.01  ? 187 PHE R C   1 
ATOM   6964 O O   . PHE F 6 196 ? 130.773 128.702 148.489 1.00 21.01  ? 187 PHE R O   1 
ATOM   6965 C CB  . PHE F 6 196 ? 129.888 127.206 145.673 1.00 21.01  ? 187 PHE R CB  1 
ATOM   6966 C CG  . PHE F 6 196 ? 129.337 125.821 145.499 1.00 21.01  ? 187 PHE R CG  1 
ATOM   6967 C CD1 . PHE F 6 196 ? 129.443 124.888 146.514 1.00 21.01  ? 187 PHE R CD1 1 
ATOM   6968 C CD2 . PHE F 6 196 ? 128.736 125.444 144.315 1.00 21.01  ? 187 PHE R CD2 1 
ATOM   6969 C CE1 . PHE F 6 196 ? 128.946 123.614 146.356 1.00 21.01  ? 187 PHE R CE1 1 
ATOM   6970 C CE2 . PHE F 6 196 ? 128.238 124.169 144.153 1.00 21.01  ? 187 PHE R CE2 1 
ATOM   6971 C CZ  . PHE F 6 196 ? 128.345 123.256 145.175 1.00 21.01  ? 187 PHE R CZ  1 
ATOM   6972 N N   . ILE F 6 197 ? 130.478 130.094 146.741 1.00 24.75  ? 188 ILE R N   1 
ATOM   6973 C CA  . ILE F 6 197 ? 131.451 131.052 147.254 1.00 24.75  ? 188 ILE R CA  1 
ATOM   6974 C C   . ILE F 6 197 ? 130.990 131.607 148.594 1.00 24.75  ? 188 ILE R C   1 
ATOM   6975 O O   . ILE F 6 197 ? 131.786 131.751 149.533 1.00 24.75  ? 188 ILE R O   1 
ATOM   6976 C CB  . ILE F 6 197 ? 131.687 132.170 146.223 1.00 24.75  ? 188 ILE R CB  1 
ATOM   6977 C CG1 . ILE F 6 197 ? 132.706 131.709 145.180 1.00 24.75  ? 188 ILE R CG1 1 
ATOM   6978 C CG2 . ILE F 6 197 ? 132.163 133.443 146.909 1.00 24.75  ? 188 ILE R CG2 1 
ATOM   6979 C CD1 . ILE F 6 197 ? 132.810 132.617 143.975 1.00 24.75  ? 188 ILE R CD1 1 
ATOM   6980 N N   . LEU F 6 198 ? 129.703 131.936 148.706 1.00 22.25  ? 189 LEU R N   1 
ATOM   6981 C CA  . LEU F 6 198 ? 129.189 132.443 149.972 1.00 22.25  ? 189 LEU R CA  1 
ATOM   6982 C C   . LEU F 6 198 ? 129.323 131.402 151.074 1.00 22.25  ? 189 LEU R C   1 
ATOM   6983 O O   . LEU F 6 198 ? 129.656 131.738 152.216 1.00 22.25  ? 189 LEU R O   1 
ATOM   6984 C CB  . LEU F 6 198 ? 127.729 132.871 149.821 1.00 22.25  ? 189 LEU R CB  1 
ATOM   6985 C CG  . LEU F 6 198 ? 127.428 134.074 148.924 1.00 22.25  ? 189 LEU R CG  1 
ATOM   6986 C CD1 . LEU F 6 198 ? 126.029 134.589 149.209 1.00 22.25  ? 189 LEU R CD1 1 
ATOM   6987 C CD2 . LEU F 6 198 ? 128.452 135.182 149.105 1.00 22.25  ? 189 LEU R CD2 1 
ATOM   6988 N N   . ARG F 6 199 ? 129.079 130.133 150.754 1.00 24.17  ? 190 ARG R N   1 
ATOM   6989 C CA  . ARG F 6 199 ? 129.172 129.035 151.748 1.00 24.17  ? 190 ARG R CA  1 
ATOM   6990 C C   . ARG F 6 199 ? 130.614 128.933 152.234 1.00 24.17  ? 190 ARG R C   1 
ATOM   6991 O O   . ARG F 6 199 ? 130.799 128.736 153.437 1.00 24.17  ? 190 ARG R O   1 
ATOM   6992 C CB  . ARG F 6 199 ? 128.737 127.698 151.153 1.00 24.17  ? 190 ARG R CB  1 
ATOM   6993 C CG  . ARG F 6 199 ? 128.974 126.515 152.077 1.00 24.17  ? 190 ARG R CG  1 
ATOM   6994 C CD  . ARG F 6 199 ? 128.117 125.330 151.691 1.00 24.17  ? 190 ARG R CD  1 
ATOM   6995 N NE  . ARG F 6 199 ? 128.087 124.333 152.746 1.00 24.17  ? 190 ARG R NE  1 
ATOM   6996 C CZ  . ARG F 6 199 ? 127.300 123.267 152.753 1.00 24.17  ? 190 ARG R CZ  1 
ATOM   6997 N NH1 . ARG F 6 199 ? 126.460 123.049 151.756 1.00 24.17  ? 190 ARG R NH1 1 
ATOM   6998 N NH2 . ARG F 6 199 ? 127.349 122.423 153.766 1.00 24.17  ? 190 ARG R NH2 1 
ATOM   6999 N N   . ALA F 6 200 ? 131.596 129.039 151.335 1.00 27.81  ? 191 ALA R N   1 
ATOM   7000 C CA  . ALA F 6 200 ? 132.999 128.984 151.736 1.00 27.81  ? 191 ALA R CA  1 
ATOM   7001 C C   . ALA F 6 200 ? 133.369 130.177 152.611 1.00 27.81  ? 191 ALA R C   1 
ATOM   7002 O O   . ALA F 6 200 ? 134.045 130.023 153.639 1.00 27.81  ? 191 ALA R O   1 
ATOM   7003 C CB  . ALA F 6 200 ? 133.894 128.926 150.499 1.00 27.81  ? 191 ALA R CB  1 
ATOM   7004 N N   . LEU F 6 201 ? 132.932 131.378 152.221 1.00 28.77  ? 192 LEU R N   1 
ATOM   7005 C CA  . LEU F 6 201 ? 133.261 132.565 153.004 1.00 28.77  ? 192 LEU R CA  1 
ATOM   7006 C C   . LEU F 6 201 ? 132.658 132.485 154.401 1.00 28.77  ? 192 LEU R C   1 
ATOM   7007 O O   . LEU F 6 201 ? 133.304 132.858 155.387 1.00 28.77  ? 192 LEU R O   1 
ATOM   7008 C CB  . LEU F 6 201 ? 132.774 133.823 152.287 1.00 28.77  ? 192 LEU R CB  1 
ATOM   7009 C CG  . LEU F 6 201 ? 133.515 134.229 151.010 1.00 28.77  ? 192 LEU R CG  1 
ATOM   7010 C CD1 . LEU F 6 201 ? 133.001 135.566 150.510 1.00 28.77  ? 192 LEU R CD1 1 
ATOM   7011 C CD2 . LEU F 6 201 ? 135.018 134.287 151.231 1.00 28.77  ? 192 LEU R CD2 1 
ATOM   7012 N N   . SER F 6 202 ? 131.417 132.009 154.505 1.00 30.73  ? 193 SER R N   1 
ATOM   7013 C CA  . SER F 6 202 ? 130.793 131.881 155.817 1.00 30.73  ? 193 SER R CA  1 
ATOM   7014 C C   . SER F 6 202 ? 131.555 130.890 156.682 1.00 30.73  ? 193 SER R C   1 
ATOM   7015 O O   . SER F 6 202 ? 131.728 131.110 157.887 1.00 30.73  ? 193 SER R O   1 
ATOM   7016 C CB  . SER F 6 202 ? 129.335 131.451 155.672 1.00 30.73  ? 193 SER R CB  1 
ATOM   7017 O OG  . SER F 6 202 ? 129.232 130.047 155.539 1.00 30.73  ? 193 SER R OG  1 
ATOM   7018 N N   . VAL F 6 203 ? 132.016 129.787 156.088 1.00 34.24  ? 194 VAL R N   1 
ATOM   7019 C CA  . VAL F 6 203 ? 132.796 128.823 156.861 1.00 34.24  ? 194 VAL R CA  1 
ATOM   7020 C C   . VAL F 6 203 ? 134.078 129.467 157.371 1.00 34.24  ? 194 VAL R C   1 
ATOM   7021 O O   . VAL F 6 203 ? 134.471 129.271 158.528 1.00 34.24  ? 194 VAL R O   1 
ATOM   7022 C CB  . VAL F 6 203 ? 133.086 127.568 156.021 1.00 34.24  ? 194 VAL R CB  1 
ATOM   7023 C CG1 . VAL F 6 203 ? 134.144 126.715 156.697 1.00 34.24  ? 194 VAL R CG1 1 
ATOM   7024 C CG2 . VAL F 6 203 ? 131.811 126.770 155.816 1.00 34.24  ? 194 VAL R CG2 1 
ATOM   7025 N N   . PHE F 6 204 ? 134.754 130.240 156.519 1.00 35.41  ? 195 PHE R N   1 
ATOM   7026 C CA  . PHE F 6 204 ? 135.979 130.908 156.957 1.00 35.41  ? 195 PHE R CA  1 
ATOM   7027 C C   . PHE F 6 204 ? 135.702 131.878 158.101 1.00 35.41  ? 195 PHE R C   1 
ATOM   7028 O O   . PHE F 6 204 ? 136.465 131.943 159.076 1.00 35.41  ? 195 PHE R O   1 
ATOM   7029 C CB  . PHE F 6 204 ? 136.625 131.646 155.783 1.00 35.41  ? 195 PHE R CB  1 
ATOM   7030 C CG  . PHE F 6 204 ? 137.308 130.742 154.797 1.00 35.41  ? 195 PHE R CG  1 
ATOM   7031 C CD1 . PHE F 6 204 ? 138.292 129.861 155.207 1.00 35.41  ? 195 PHE R CD1 1 
ATOM   7032 C CD2 . PHE F 6 204 ? 136.969 130.780 153.456 1.00 35.41  ? 195 PHE R CD2 1 
ATOM   7033 C CE1 . PHE F 6 204 ? 138.920 129.033 154.301 1.00 35.41  ? 195 PHE R CE1 1 
ATOM   7034 C CE2 . PHE F 6 204 ? 137.593 129.956 152.546 1.00 35.41  ? 195 PHE R CE2 1 
ATOM   7035 C CZ  . PHE F 6 204 ? 138.570 129.081 152.969 1.00 35.41  ? 195 PHE R CZ  1 
ATOM   7036 N N   . ILE F 6 205 ? 134.618 132.648 157.997 1.00 39.91  ? 196 ILE R N   1 
ATOM   7037 C CA  . ILE F 6 205 ? 134.287 133.607 159.048 1.00 39.91  ? 196 ILE R CA  1 
ATOM   7038 C C   . ILE F 6 205 ? 133.986 132.884 160.353 1.00 39.91  ? 196 ILE R C   1 
ATOM   7039 O O   . ILE F 6 205 ? 134.391 133.327 161.435 1.00 39.91  ? 196 ILE R O   1 
ATOM   7040 C CB  . ILE F 6 205 ? 133.108 134.495 158.611 1.00 39.91  ? 196 ILE R CB  1 
ATOM   7041 C CG1 . ILE F 6 205 ? 133.501 135.363 157.411 1.00 39.91  ? 196 ILE R CG1 1 
ATOM   7042 C CG2 . ILE F 6 205 ? 132.641 135.360 159.767 1.00 39.91  ? 196 ILE R CG2 1 
ATOM   7043 C CD1 . ILE F 6 205 ? 134.650 136.317 157.672 1.00 39.91  ? 196 ILE R CD1 1 
ATOM   7044 N N   . LYS F 6 206 ? 133.253 131.772 160.278 1.00 44.70  ? 197 LYS R N   1 
ATOM   7045 C CA  . LYS F 6 206 ? 132.973 130.994 161.480 1.00 44.70  ? 197 LYS R CA  1 
ATOM   7046 C C   . LYS F 6 206 ? 134.262 130.469 162.099 1.00 44.70  ? 197 LYS R C   1 
ATOM   7047 O O   . LYS F 6 206 ? 134.418 130.468 163.328 1.00 44.70  ? 197 LYS R O   1 
ATOM   7048 C CB  . LYS F 6 206 ? 132.026 129.844 161.139 1.00 44.70  ? 197 LYS R CB  1 
ATOM   7049 C CG  . LYS F 6 206 ? 131.783 128.868 162.274 1.00 44.70  ? 197 LYS R CG  1 
ATOM   7050 C CD  . LYS F 6 206 ? 132.702 127.657 162.193 1.00 44.70  ? 197 LYS R CD  1 
ATOM   7051 C CE  . LYS F 6 206 ? 132.260 126.683 161.114 1.00 44.70  ? 197 LYS R CE  1 
ATOM   7052 N NZ  . LYS F 6 206 ? 133.238 125.574 160.940 1.00 44.70  ? 197 LYS R NZ  1 
ATOM   7053 N N   . ASP F 6 207 ? 135.192 130.004 161.263 1.00 47.75  ? 198 ASP R N   1 
ATOM   7054 C CA  . ASP F 6 207 ? 136.497 129.581 161.761 1.00 47.75  ? 198 ASP R CA  1 
ATOM   7055 C C   . ASP F 6 207 ? 137.175 130.707 162.528 1.00 47.75  ? 198 ASP R C   1 
ATOM   7056 O O   . ASP F 6 207 ? 137.690 130.505 163.636 1.00 47.75  ? 198 ASP R O   1 
ATOM   7057 C CB  . ASP F 6 207 ? 137.375 129.136 160.592 1.00 47.75  ? 198 ASP R CB  1 
ATOM   7058 C CG  . ASP F 6 207 ? 136.922 127.824 159.987 1.00 47.75  ? 198 ASP R CG  1 
ATOM   7059 O OD1 . ASP F 6 207 ? 136.119 127.113 160.627 1.00 47.75  ? 198 ASP R OD1 1 
ATOM   7060 O OD2 . ASP F 6 207 ? 137.395 127.489 158.883 1.00 47.75  ? 198 ASP R OD2 1 
ATOM   7061 N N   . ALA F 6 208 ? 137.192 131.904 161.942 1.00 50.84  ? 199 ALA R N   1 
ATOM   7062 C CA  . ALA F 6 208 ? 137.830 133.034 162.607 1.00 50.84  ? 199 ALA R CA  1 
ATOM   7063 C C   . ALA F 6 208 ? 137.156 133.334 163.938 1.00 50.84  ? 199 ALA R C   1 
ATOM   7064 O O   . ALA F 6 208 ? 137.830 133.611 164.938 1.00 50.84  ? 199 ALA R O   1 
ATOM   7065 C CB  . ALA F 6 208 ? 137.799 134.265 161.702 1.00 50.84  ? 199 ALA R CB  1 
ATOM   7066 N N   . ALA F 6 209 ? 135.823 133.291 163.968 1.00 54.74  ? 200 ALA R N   1 
ATOM   7067 C CA  . ALA F 6 209 ? 135.101 133.591 165.200 1.00 54.74  ? 200 ALA R CA  1 
ATOM   7068 C C   . ALA F 6 209 ? 135.438 132.583 166.292 1.00 54.74  ? 200 ALA R C   1 
ATOM   7069 O O   . ALA F 6 209 ? 135.697 132.959 167.442 1.00 54.74  ? 200 ALA R O   1 
ATOM   7070 C CB  . ALA F 6 209 ? 133.597 133.613 164.934 1.00 54.74  ? 200 ALA R CB  1 
ATOM   7071 N N   . LEU F 6 210 ? 135.442 131.293 165.952 1.00 56.56  ? 201 LEU R N   1 
ATOM   7072 C CA  . LEU F 6 210 ? 135.793 130.283 166.946 1.00 56.56  ? 201 LEU R CA  1 
ATOM   7073 C C   . LEU F 6 210 ? 137.220 130.468 167.441 1.00 56.56  ? 201 LEU R C   1 
ATOM   7074 O O   . LEU F 6 210 ? 137.485 130.359 168.644 1.00 56.56  ? 201 LEU R O   1 
ATOM   7075 C CB  . LEU F 6 210 ? 135.603 128.873 166.382 1.00 56.56  ? 201 LEU R CB  1 
ATOM   7076 C CG  . LEU F 6 210 ? 134.196 128.265 166.422 1.00 56.56  ? 201 LEU R CG  1 
ATOM   7077 C CD1 . LEU F 6 210 ? 133.736 128.080 167.862 1.00 56.56  ? 201 LEU R CD1 1 
ATOM   7078 C CD2 . LEU F 6 210 ? 133.187 129.090 165.647 1.00 56.56  ? 201 LEU R CD2 1 
ATOM   7079 N N   . LYS F 6 211 ? 138.157 130.750 166.533 1.00 59.20  ? 202 LYS R N   1 
ATOM   7080 C CA  . LYS F 6 211 ? 139.535 130.957 166.966 1.00 59.20  ? 202 LYS R CA  1 
ATOM   7081 C C   . LYS F 6 211 ? 139.641 132.146 167.912 1.00 59.20  ? 202 LYS R C   1 
ATOM   7082 O O   . LYS F 6 211 ? 140.345 132.082 168.926 1.00 59.20  ? 202 LYS R O   1 
ATOM   7083 C CB  . LYS F 6 211 ? 140.448 131.151 165.757 1.00 59.20  ? 202 LYS R CB  1 
ATOM   7084 C CG  . LYS F 6 211 ? 141.194 129.894 165.354 1.00 59.20  ? 202 LYS R CG  1 
ATOM   7085 C CD  . LYS F 6 211 ? 142.317 130.200 164.384 1.00 59.20  ? 202 LYS R CD  1 
ATOM   7086 C CE  . LYS F 6 211 ? 143.200 128.986 164.161 1.00 59.20  ? 202 LYS R CE  1 
ATOM   7087 N NZ  . LYS F 6 211 ? 143.932 128.594 165.398 1.00 59.20  ? 202 LYS R NZ  1 
ATOM   7088 N N   . TRP F 6 212 ? 138.946 133.240 167.597 1.00 71.62  ? 203 TRP R N   1 
ATOM   7089 C CA  . TRP F 6 212 ? 139.004 134.419 168.455 1.00 71.62  ? 203 TRP R CA  1 
ATOM   7090 C C   . TRP F 6 212 ? 138.381 134.145 169.818 1.00 71.62  ? 203 TRP R C   1 
ATOM   7091 O O   . TRP F 6 212 ? 138.887 134.618 170.843 1.00 71.62  ? 203 TRP R O   1 
ATOM   7092 C CB  . TRP F 6 212 ? 138.305 135.597 167.776 1.00 71.62  ? 203 TRP R CB  1 
ATOM   7093 C CG  . TRP F 6 212 ? 138.435 136.892 168.524 1.00 71.62  ? 203 TRP R CG  1 
ATOM   7094 C CD1 . TRP F 6 212 ? 137.861 137.213 169.721 1.00 71.62  ? 203 TRP R CD1 1 
ATOM   7095 C CD2 . TRP F 6 212 ? 139.185 138.044 168.120 1.00 71.62  ? 203 TRP R CD2 1 
ATOM   7096 N NE1 . TRP F 6 212 ? 138.209 138.489 170.088 1.00 71.62  ? 203 TRP R NE1 1 
ATOM   7097 C CE2 . TRP F 6 212 ? 139.022 139.021 169.122 1.00 71.62  ? 203 TRP R CE2 1 
ATOM   7098 C CE3 . TRP F 6 212 ? 139.979 138.343 167.009 1.00 71.62  ? 203 TRP R CE3 1 
ATOM   7099 C CZ2 . TRP F 6 212 ? 139.623 140.276 169.045 1.00 71.62  ? 203 TRP R CZ2 1 
ATOM   7100 C CZ3 . TRP F 6 212 ? 140.575 139.589 166.935 1.00 71.62  ? 203 TRP R CZ3 1 
ATOM   7101 C CH2 . TRP F 6 212 ? 140.393 140.540 167.947 1.00 71.62  ? 203 TRP R CH2 1 
ATOM   7102 N N   . MET F 6 213 ? 137.282 133.389 169.853 1.00 72.44  ? 204 MET R N   1 
ATOM   7103 C CA  . MET F 6 213 ? 136.560 133.202 171.107 1.00 72.44  ? 204 MET R CA  1 
ATOM   7104 C C   . MET F 6 213 ? 137.433 132.531 172.159 1.00 72.44  ? 204 MET R C   1 
ATOM   7105 O O   . MET F 6 213 ? 137.411 132.919 173.333 1.00 72.44  ? 204 MET R O   1 
ATOM   7106 C CB  . MET F 6 213 ? 135.294 132.380 170.869 1.00 72.44  ? 204 MET R CB  1 
ATOM   7107 C CG  . MET F 6 213 ? 134.342 132.363 172.060 1.00 72.44  ? 204 MET R CG  1 
ATOM   7108 S SD  . MET F 6 213 ? 132.775 131.497 171.799 1.00 72.44  ? 204 MET R SD  1 
ATOM   7109 C CE  . MET F 6 213 ? 132.600 131.518 170.016 1.00 72.44  ? 204 MET R CE  1 
ATOM   7110 N N   . TYR F 6 214 ? 138.207 131.521 171.763 1.00 76.70  ? 205 TYR R N   1 
ATOM   7111 C CA  . TYR F 6 214 ? 139.035 130.757 172.686 1.00 76.70  ? 205 TYR R CA  1 
ATOM   7112 C C   . TYR F 6 214 ? 140.522 131.055 172.507 1.00 76.70  ? 205 TYR R C   1 
ATOM   7113 O O   . TYR F 6 214 ? 141.367 130.180 172.710 1.00 76.70  ? 205 TYR R O   1 
ATOM   7114 C CB  . TYR F 6 214 ? 138.766 129.262 172.525 1.00 76.70  ? 205 TYR R CB  1 
ATOM   7115 C CG  . TYR F 6 214 ? 137.368 128.861 172.933 1.00 76.70  ? 205 TYR R CG  1 
ATOM   7116 C CD1 . TYR F 6 214 ? 136.940 129.002 174.244 1.00 76.70  ? 205 TYR R CD1 1 
ATOM   7117 C CD2 . TYR F 6 214 ? 136.473 128.347 172.005 1.00 76.70  ? 205 TYR R CD2 1 
ATOM   7118 C CE1 . TYR F 6 214 ? 135.662 128.640 174.623 1.00 76.70  ? 205 TYR R CE1 1 
ATOM   7119 C CE2 . TYR F 6 214 ? 135.194 127.982 172.373 1.00 76.70  ? 205 TYR R CE2 1 
ATOM   7120 C CZ  . TYR F 6 214 ? 134.793 128.131 173.684 1.00 76.70  ? 205 TYR R CZ  1 
ATOM   7121 O OH  . TYR F 6 214 ? 133.519 127.768 174.055 1.00 76.70  ? 205 TYR R OH  1 
ATOM   7122 N N   . SER F 6 215 ? 140.853 132.283 172.121 1.00 87.50  ? 206 SER R N   1 
ATOM   7123 C CA  . SER F 6 215 ? 142.240 132.714 172.104 1.00 87.50  ? 206 SER R CA  1 
ATOM   7124 C C   . SER F 6 215 ? 142.670 133.133 173.508 1.00 87.50  ? 206 SER R C   1 
ATOM   7125 O O   . SER F 6 215 ? 141.846 133.357 174.399 1.00 87.50  ? 206 SER R O   1 
ATOM   7126 C CB  . SER F 6 215 ? 142.435 133.864 171.117 1.00 87.50  ? 206 SER R CB  1 
ATOM   7127 O OG  . SER F 6 215 ? 141.884 135.068 171.621 1.00 87.50  ? 206 SER R OG  1 
ATOM   7128 N N   . THR F 6 216 ? 143.985 133.241 173.700 1.00 100.27 ? 207 THR R N   1 
ATOM   7129 C CA  . THR F 6 216 ? 144.524 133.535 175.024 1.00 100.27 ? 207 THR R CA  1 
ATOM   7130 C C   . THR F 6 216 ? 143.899 134.800 175.601 1.00 100.27 ? 207 THR R C   1 
ATOM   7131 O O   . THR F 6 216 ? 143.309 134.782 176.688 1.00 100.27 ? 207 THR R O   1 
ATOM   7132 C CB  . THR F 6 216 ? 146.046 133.682 174.946 1.00 100.27 ? 207 THR R CB  1 
ATOM   7133 O OG1 . THR F 6 216 ? 146.382 134.734 174.032 1.00 100.27 ? 207 THR R OG1 1 
ATOM   7134 C CG2 . THR F 6 216 ? 146.697 132.385 174.477 1.00 100.27 ? 207 THR R CG2 1 
ATOM   7135 N N   . ALA F 6 217 ? 144.006 135.912 174.872 1.00 98.88  ? 208 ALA R N   1 
ATOM   7136 C CA  . ALA F 6 217 ? 143.513 137.181 175.396 1.00 98.88  ? 208 ALA R CA  1 
ATOM   7137 C C   . ALA F 6 217 ? 142.035 137.093 175.751 1.00 98.88  ? 208 ALA R C   1 
ATOM   7138 O O   . ALA F 6 217 ? 141.615 137.564 176.815 1.00 98.88  ? 208 ALA R O   1 
ATOM   7139 C CB  . ALA F 6 217 ? 143.753 138.294 174.376 1.00 98.88  ? 208 ALA R CB  1 
ATOM   7140 N N   . ALA F 6 218 ? 141.231 136.492 174.870 1.00 94.49  ? 209 ALA R N   1 
ATOM   7141 C CA  . ALA F 6 218 ? 139.797 136.402 175.119 1.00 94.49  ? 209 ALA R CA  1 
ATOM   7142 C C   . ALA F 6 218 ? 139.507 135.607 176.385 1.00 94.49  ? 209 ALA R C   1 
ATOM   7143 O O   . ALA F 6 218 ? 138.653 135.998 177.190 1.00 94.49  ? 209 ALA R O   1 
ATOM   7144 C CB  . ALA F 6 218 ? 139.096 135.769 173.917 1.00 94.49  ? 209 ALA R CB  1 
ATOM   7145 N N   . GLN F 6 219 ? 140.204 134.485 176.580 1.00 98.10  ? 210 GLN R N   1 
ATOM   7146 C CA  . GLN F 6 219 ? 139.963 133.695 177.783 1.00 98.10  ? 210 GLN R CA  1 
ATOM   7147 C C   . GLN F 6 219 ? 140.386 134.458 179.032 1.00 98.10  ? 210 GLN R C   1 
ATOM   7148 O O   . GLN F 6 219 ? 139.696 134.402 180.055 1.00 98.10  ? 210 GLN R O   1 
ATOM   7149 C CB  . GLN F 6 219 ? 140.673 132.340 177.698 1.00 98.10  ? 210 GLN R CB  1 
ATOM   7150 C CG  . GLN F 6 219 ? 142.171 132.395 177.487 1.00 98.10  ? 210 GLN R CG  1 
ATOM   7151 C CD  . GLN F 6 219 ? 142.835 131.046 177.677 1.00 98.10  ? 210 GLN R CD  1 
ATOM   7152 O OE1 . GLN F 6 219 ? 142.166 130.039 177.901 1.00 98.10  ? 210 GLN R OE1 1 
ATOM   7153 N NE2 . GLN F 6 219 ? 144.159 131.022 177.590 1.00 98.10  ? 210 GLN R NE2 1 
ATOM   7154 N N   . GLN F 6 220 ? 141.508 135.188 178.978 1.00 97.91  ? 211 GLN R N   1 
ATOM   7155 C CA  . GLN F 6 220 ? 141.893 135.975 180.149 1.00 97.91  ? 211 GLN R CA  1 
ATOM   7156 C C   . GLN F 6 220 ? 140.864 137.058 180.457 1.00 97.91  ? 211 GLN R C   1 
ATOM   7157 O O   . GLN F 6 220 ? 140.518 137.274 181.624 1.00 97.91  ? 211 GLN R O   1 
ATOM   7158 C CB  . GLN F 6 220 ? 143.284 136.595 179.983 1.00 97.91  ? 211 GLN R CB  1 
ATOM   7159 C CG  . GLN F 6 220 ? 144.438 135.602 180.123 1.00 97.91  ? 211 GLN R CG  1 
ATOM   7160 C CD  . GLN F 6 220 ? 145.072 135.212 178.808 1.00 97.91  ? 211 GLN R CD  1 
ATOM   7161 O OE1 . GLN F 6 220 ? 145.062 135.981 177.850 1.00 97.91  ? 211 GLN R OE1 1 
ATOM   7162 N NE2 . GLN F 6 220 ? 145.627 134.006 178.755 1.00 97.91  ? 211 GLN R NE2 1 
ATOM   7163 N N   . HIS F 6 221 ? 140.357 137.749 179.432 1.00 99.29  ? 212 HIS R N   1 
ATOM   7164 C CA  . HIS F 6 221 ? 139.323 138.750 179.687 1.00 99.29  ? 212 HIS R CA  1 
ATOM   7165 C C   . HIS F 6 221 ? 138.076 138.115 180.287 1.00 99.29  ? 212 HIS R C   1 
ATOM   7166 O O   . HIS F 6 221 ? 137.489 138.655 181.231 1.00 99.29  ? 212 HIS R O   1 
ATOM   7167 C CB  . HIS F 6 221 ? 138.961 139.519 178.414 1.00 99.29  ? 212 HIS R CB  1 
ATOM   7168 C CG  . HIS F 6 221 ? 140.076 140.355 177.865 1.00 99.29  ? 212 HIS R CG  1 
ATOM   7169 N ND1 . HIS F 6 221 ? 140.458 141.545 178.446 1.00 99.29  ? 212 HIS R ND1 1 
ATOM   7170 C CD2 . HIS F 6 221 ? 140.850 140.210 176.764 1.00 99.29  ? 212 HIS R CD2 1 
ATOM   7171 C CE1 . HIS F 6 221 ? 141.445 142.077 177.749 1.00 99.29  ? 212 HIS R CE1 1 
ATOM   7172 N NE2 . HIS F 6 221 ? 141.702 141.288 176.722 1.00 99.29  ? 212 HIS R NE2 1 
ATOM   7173 N N   . GLN F 6 222 ? 137.657 136.963 179.761 1.00 96.24  ? 213 GLN R N   1 
ATOM   7174 C CA  . GLN F 6 222 ? 136.469 136.311 180.299 1.00 96.24  ? 213 GLN R CA  1 
ATOM   7175 C C   . GLN F 6 222 ? 136.694 135.822 181.724 1.00 96.24  ? 213 GLN R C   1 
ATOM   7176 O O   . GLN F 6 222 ? 135.742 135.758 182.510 1.00 96.24  ? 213 GLN R O   1 
ATOM   7177 C CB  . GLN F 6 222 ? 136.049 135.154 179.395 1.00 96.24  ? 213 GLN R CB  1 
ATOM   7178 C CG  . GLN F 6 222 ? 135.385 135.605 178.105 1.00 96.24  ? 213 GLN R CG  1 
ATOM   7179 C CD  . GLN F 6 222 ? 135.381 134.526 177.044 1.00 96.24  ? 213 GLN R CD  1 
ATOM   7180 O OE1 . GLN F 6 222 ? 136.025 134.658 176.004 1.00 96.24  ? 213 GLN R OE1 1 
ATOM   7181 N NE2 . GLN F 6 222 ? 134.651 133.448 177.302 1.00 96.24  ? 213 GLN R NE2 1 
ATOM   7182 N N   . TRP F 6 223 ? 137.934 135.476 182.077 1.00 102.03 ? 214 TRP R N   1 
ATOM   7183 C CA  . TRP F 6 223 ? 138.219 135.074 183.450 1.00 102.03 ? 214 TRP R CA  1 
ATOM   7184 C C   . TRP F 6 223 ? 137.921 136.206 184.423 1.00 102.03 ? 214 TRP R C   1 
ATOM   7185 O O   . TRP F 6 223 ? 137.374 135.977 185.507 1.00 102.03 ? 214 TRP R O   1 
ATOM   7186 C CB  . TRP F 6 223 ? 139.677 134.633 183.583 1.00 102.03 ? 214 TRP R CB  1 
ATOM   7187 C CG  . TRP F 6 223 ? 140.027 133.417 182.785 1.00 102.03 ? 214 TRP R CG  1 
ATOM   7188 C CD1 . TRP F 6 223 ? 139.161 132.539 182.202 1.00 102.03 ? 214 TRP R CD1 1 
ATOM   7189 C CD2 . TRP F 6 223 ? 141.344 132.940 182.486 1.00 102.03 ? 214 TRP R CD2 1 
ATOM   7190 N NE1 . TRP F 6 223 ? 139.856 131.547 181.556 1.00 102.03 ? 214 TRP R NE1 1 
ATOM   7191 C CE2 . TRP F 6 223 ? 141.199 131.769 181.717 1.00 102.03 ? 214 TRP R CE2 1 
ATOM   7192 C CE3 . TRP F 6 223 ? 142.632 133.389 182.795 1.00 102.03 ? 214 TRP R CE3 1 
ATOM   7193 C CZ2 . TRP F 6 223 ? 142.293 131.043 181.251 1.00 102.03 ? 214 TRP R CZ2 1 
ATOM   7194 C CZ3 . TRP F 6 223 ? 143.715 132.666 182.332 1.00 102.03 ? 214 TRP R CZ3 1 
ATOM   7195 C CH2 . TRP F 6 223 ? 143.539 131.507 181.568 1.00 102.03 ? 214 TRP R CH2 1 
ATOM   7196 N N   . ASP F 6 224 ? 138.275 137.436 184.050 1.00 107.53 ? 215 ASP R N   1 
ATOM   7197 C CA  . ASP F 6 224 ? 138.051 138.590 184.911 1.00 107.53 ? 215 ASP R CA  1 
ATOM   7198 C C   . ASP F 6 224 ? 136.574 138.913 185.091 1.00 107.53 ? 215 ASP R C   1 
ATOM   7199 O O   . ASP F 6 224 ? 136.240 139.731 185.955 1.00 107.53 ? 215 ASP R O   1 
ATOM   7200 C CB  . ASP F 6 224 ? 138.778 139.808 184.341 1.00 107.53 ? 215 ASP R CB  1 
ATOM   7201 N N   . SER F 6 228 ? 132.570 139.673 177.059 1.00 86.12  ? 219 SER R N   1 
ATOM   7202 C CA  . SER F 6 228 ? 133.415 139.340 175.922 1.00 86.12  ? 219 SER R CA  1 
ATOM   7203 C C   . SER F 6 228 ? 132.542 139.101 174.689 1.00 86.12  ? 219 SER R C   1 
ATOM   7204 O O   . SER F 6 228 ? 131.330 139.335 174.700 1.00 86.12  ? 219 SER R O   1 
ATOM   7205 C CB  . SER F 6 228 ? 134.282 138.122 176.244 1.00 86.12  ? 219 SER R CB  1 
ATOM   7206 N N   . TYR F 6 229 ? 133.178 138.626 173.617 1.00 79.37  ? 220 TYR R N   1 
ATOM   7207 C CA  . TYR F 6 229 ? 132.459 138.298 172.394 1.00 79.37  ? 220 TYR R CA  1 
ATOM   7208 C C   . TYR F 6 229 ? 131.497 137.135 172.585 1.00 79.37  ? 220 TYR R C   1 
ATOM   7209 O O   . TYR F 6 229 ? 130.651 136.899 171.717 1.00 79.37  ? 220 TYR R O   1 
ATOM   7210 C CB  . TYR F 6 229 ? 133.457 137.969 171.282 1.00 79.37  ? 220 TYR R CB  1 
ATOM   7211 C CG  . TYR F 6 229 ? 132.918 138.182 169.886 1.00 79.37  ? 220 TYR R CG  1 
ATOM   7212 C CD1 . TYR F 6 229 ? 132.607 139.455 169.430 1.00 79.37  ? 220 TYR R CD1 1 
ATOM   7213 C CD2 . TYR F 6 229 ? 132.725 137.112 169.024 1.00 79.37  ? 220 TYR R CD2 1 
ATOM   7214 C CE1 . TYR F 6 229 ? 132.115 139.657 168.156 1.00 79.37  ? 220 TYR R CE1 1 
ATOM   7215 C CE2 . TYR F 6 229 ? 132.235 137.304 167.748 1.00 79.37  ? 220 TYR R CE2 1 
ATOM   7216 C CZ  . TYR F 6 229 ? 131.932 138.579 167.319 1.00 79.37  ? 220 TYR R CZ  1 
ATOM   7217 O OH  . TYR F 6 229 ? 131.442 138.777 166.048 1.00 79.37  ? 220 TYR R OH  1 
ATOM   7218 N N   . GLN F 6 230 ? 131.603 136.411 173.701 1.00 81.54  ? 221 GLN R N   1 
ATOM   7219 C CA  . GLN F 6 230 ? 130.776 135.238 173.948 1.00 81.54  ? 221 GLN R CA  1 
ATOM   7220 C C   . GLN F 6 230 ? 129.297 135.571 174.076 1.00 81.54  ? 221 GLN R C   1 
ATOM   7221 O O   . GLN F 6 230 ? 128.470 134.655 174.032 1.00 81.54  ? 221 GLN R O   1 
ATOM   7222 C CB  . GLN F 6 230 ? 131.271 134.538 175.216 1.00 81.54  ? 221 GLN R CB  1 
ATOM   7223 C CG  . GLN F 6 230 ? 130.624 133.193 175.509 1.00 81.54  ? 221 GLN R CG  1 
ATOM   7224 C CD  . GLN F 6 230 ? 129.449 133.297 176.463 1.00 81.54  ? 221 GLN R CD  1 
ATOM   7225 O OE1 . GLN F 6 230 ? 129.279 134.301 177.155 1.00 81.54  ? 221 GLN R OE1 1 
ATOM   7226 N NE2 . GLN F 6 230 ? 128.646 132.244 176.524 1.00 81.54  ? 221 GLN R NE2 1 
ATOM   7227 N N   . ASP F 6 231 ? 128.940 136.848 174.236 1.00 74.01  ? 222 ASP R N   1 
ATOM   7228 C CA  . ASP F 6 231 ? 127.545 137.250 174.343 1.00 74.01  ? 222 ASP R CA  1 
ATOM   7229 C C   . ASP F 6 231 ? 127.151 138.373 173.393 1.00 74.01  ? 222 ASP R C   1 
ATOM   7230 O O   . ASP F 6 231 ? 125.970 138.734 173.360 1.00 74.01  ? 222 ASP R O   1 
ATOM   7231 C CB  . ASP F 6 231 ? 127.224 137.687 175.781 1.00 74.01  ? 222 ASP R CB  1 
ATOM   7232 C CG  . ASP F 6 231 ? 125.762 137.504 176.132 1.00 74.01  ? 222 ASP R CG  1 
ATOM   7233 O OD1 . ASP F 6 231 ? 124.928 138.307 175.662 1.00 74.01  ? 222 ASP R OD1 1 
ATOM   7234 O OD2 . ASP F 6 231 ? 125.443 136.554 176.878 1.00 74.01  ? 222 ASP R OD2 1 
ATOM   7235 N N   . SER F 6 232 ? 128.081 138.927 172.623 1.00 74.69  ? 223 SER R N   1 
ATOM   7236 C CA  . SER F 6 232 ? 127.747 140.003 171.702 1.00 74.69  ? 223 SER R CA  1 
ATOM   7237 C C   . SER F 6 232 ? 126.860 139.492 170.572 1.00 74.69  ? 223 SER R C   1 
ATOM   7238 O O   . SER F 6 232 ? 126.875 138.308 170.225 1.00 74.69  ? 223 SER R O   1 
ATOM   7239 C CB  . SER F 6 232 ? 129.019 140.627 171.129 1.00 74.69  ? 223 SER R CB  1 
ATOM   7240 O OG  . SER F 6 232 ? 129.821 139.650 170.492 1.00 74.69  ? 223 SER R OG  1 
ATOM   7241 N N   . LEU F 6 233 ? 126.077 140.406 169.995 1.00 67.24  ? 224 LEU R N   1 
ATOM   7242 C CA  . LEU F 6 233 ? 125.150 140.023 168.935 1.00 67.24  ? 224 LEU R CA  1 
ATOM   7243 C C   . LEU F 6 233 ? 125.878 139.585 167.671 1.00 67.24  ? 224 LEU R C   1 
ATOM   7244 O O   . LEU F 6 233 ? 125.376 138.725 166.937 1.00 67.24  ? 224 LEU R O   1 
ATOM   7245 C CB  . LEU F 6 233 ? 124.208 141.184 168.621 1.00 67.24  ? 224 LEU R CB  1 
ATOM   7246 C CG  . LEU F 6 233 ? 122.888 141.184 169.392 1.00 67.24  ? 224 LEU R CG  1 
ATOM   7247 C CD1 . LEU F 6 233 ? 123.139 141.067 170.888 1.00 67.24  ? 224 LEU R CD1 1 
ATOM   7248 C CD2 . LEU F 6 233 ? 122.086 142.436 169.077 1.00 67.24  ? 224 LEU R CD2 1 
ATOM   7249 N N   . SER F 6 234 ? 127.054 140.158 167.401 1.00 70.42  ? 225 SER R N   1 
ATOM   7250 C CA  . SER F 6 234 ? 127.768 139.842 166.169 1.00 70.42  ? 225 SER R CA  1 
ATOM   7251 C C   . SER F 6 234 ? 127.982 138.341 166.021 1.00 70.42  ? 225 SER R C   1 
ATOM   7252 O O   . SER F 6 234 ? 127.936 137.805 164.908 1.00 70.42  ? 225 SER R O   1 
ATOM   7253 C CB  . SER F 6 234 ? 129.107 140.579 166.142 1.00 70.42  ? 225 SER R CB  1 
ATOM   7254 O OG  . SER F 6 234 ? 129.860 140.230 164.994 1.00 70.42  ? 225 SER R OG  1 
ATOM   7255 N N   . CYS F 6 235 ? 128.216 137.645 167.134 1.00 71.14  ? 226 CYS R N   1 
ATOM   7256 C CA  . CYS F 6 235 ? 128.396 136.198 167.088 1.00 71.14  ? 226 CYS R CA  1 
ATOM   7257 C C   . CYS F 6 235 ? 127.137 135.509 166.569 1.00 71.14  ? 226 CYS R C   1 
ATOM   7258 O O   . CYS F 6 235 ? 127.197 134.641 165.684 1.00 71.14  ? 226 CYS R O   1 
ATOM   7259 C CB  . CYS F 6 235 ? 128.759 135.700 168.487 1.00 71.14  ? 226 CYS R CB  1 
ATOM   7260 S SG  . CYS F 6 235 ? 129.402 134.029 168.580 1.00 71.14  ? 226 CYS R SG  1 
ATOM   7261 N N   . ARG F 6 236 ? 125.980 135.898 167.109 1.00 62.52  ? 227 ARG R N   1 
ATOM   7262 C CA  . ARG F 6 236 ? 124.721 135.316 166.664 1.00 62.52  ? 227 ARG R CA  1 
ATOM   7263 C C   . ARG F 6 236 ? 124.465 135.628 165.196 1.00 62.52  ? 227 ARG R C   1 
ATOM   7264 O O   . ARG F 6 236 ? 123.993 134.768 164.440 1.00 62.52  ? 227 ARG R O   1 
ATOM   7265 C CB  . ARG F 6 236 ? 123.581 135.837 167.536 1.00 62.52  ? 227 ARG R CB  1 
ATOM   7266 C CG  . ARG F 6 236 ? 123.634 135.336 168.971 1.00 62.52  ? 227 ARG R CG  1 
ATOM   7267 C CD  . ARG F 6 236 ? 122.630 136.059 169.857 1.00 62.52  ? 227 ARG R CD  1 
ATOM   7268 N NE  . ARG F 6 236 ? 122.643 135.555 171.226 1.00 62.52  ? 227 ARG R NE  1 
ATOM   7269 C CZ  . ARG F 6 236 ? 123.378 136.058 172.210 1.00 62.52  ? 227 ARG R CZ  1 
ATOM   7270 N NH1 . ARG F 6 236 ? 124.185 137.088 172.017 1.00 62.52  ? 227 ARG R NH1 1 
ATOM   7271 N NH2 . ARG F 6 236 ? 123.300 135.511 173.420 1.00 62.52  ? 227 ARG R NH2 1 
ATOM   7272 N N   . LEU F 6 237 ? 124.773 136.855 164.772 1.00 56.16  ? 228 LEU R N   1 
ATOM   7273 C CA  . LEU F 6 237 ? 124.617 137.206 163.365 1.00 56.16  ? 228 LEU R CA  1 
ATOM   7274 C C   . LEU F 6 237 ? 125.497 136.332 162.481 1.00 56.16  ? 228 LEU R C   1 
ATOM   7275 O O   . LEU F 6 237 ? 125.059 135.869 161.422 1.00 56.16  ? 228 LEU R O   1 
ATOM   7276 C CB  . LEU F 6 237 ? 124.943 138.684 163.149 1.00 56.16  ? 228 LEU R CB  1 
ATOM   7277 C CG  . LEU F 6 237 ? 123.826 139.701 163.402 1.00 56.16  ? 228 LEU R CG  1 
ATOM   7278 C CD1 . LEU F 6 237 ? 122.686 139.507 162.414 1.00 56.16  ? 228 LEU R CD1 1 
ATOM   7279 C CD2 . LEU F 6 237 ? 123.310 139.627 164.832 1.00 56.16  ? 228 LEU R CD2 1 
ATOM   7280 N N   . VAL F 6 238 ? 126.741 136.096 162.898 1.00 50.15  ? 229 VAL R N   1 
ATOM   7281 C CA  . VAL F 6 238 ? 127.651 135.273 162.105 1.00 50.15  ? 229 VAL R CA  1 
ATOM   7282 C C   . VAL F 6 238 ? 127.092 133.863 161.958 1.00 50.15  ? 229 VAL R C   1 
ATOM   7283 O O   . VAL F 6 238 ? 127.089 133.281 160.862 1.00 50.15  ? 229 VAL R O   1 
ATOM   7284 C CB  . VAL F 6 238 ? 129.049 135.256 162.748 1.00 50.15  ? 229 VAL R CB  1 
ATOM   7285 C CG1 . VAL F 6 238 ? 129.914 134.177 162.116 1.00 50.15  ? 229 VAL R CG1 1 
ATOM   7286 C CG2 . VAL F 6 238 ? 129.703 136.622 162.626 1.00 50.15  ? 229 VAL R CG2 1 
ATOM   7287 N N   . PHE F 6 239 ? 126.614 133.289 163.063 1.00 48.45  ? 230 PHE R N   1 
ATOM   7288 C CA  . PHE F 6 239 ? 126.095 131.925 162.995 1.00 48.45  ? 230 PHE R CA  1 
ATOM   7289 C C   . PHE F 6 239 ? 124.856 131.849 162.110 1.00 48.45  ? 230 PHE R C   1 
ATOM   7290 O O   . PHE F 6 239 ? 124.717 130.922 161.297 1.00 48.45  ? 230 PHE R O   1 
ATOM   7291 C CB  . PHE F 6 239 ? 125.797 131.412 164.402 1.00 48.45  ? 230 PHE R CB  1 
ATOM   7292 C CG  . PHE F 6 239 ? 127.023 130.977 165.156 1.00 48.45  ? 230 PHE R CG  1 
ATOM   7293 C CD1 . PHE F 6 239 ? 128.249 131.582 164.925 1.00 48.45  ? 230 PHE R CD1 1 
ATOM   7294 C CD2 . PHE F 6 239 ? 126.954 129.960 166.089 1.00 48.45  ? 230 PHE R CD2 1 
ATOM   7295 C CE1 . PHE F 6 239 ? 129.376 131.184 165.612 1.00 48.45  ? 230 PHE R CE1 1 
ATOM   7296 C CE2 . PHE F 6 239 ? 128.081 129.560 166.779 1.00 48.45  ? 230 PHE R CE2 1 
ATOM   7297 C CZ  . PHE F 6 239 ? 129.292 130.172 166.540 1.00 48.45  ? 230 PHE R CZ  1 
ATOM   7298 N N   . LEU F 6 240 ? 123.951 132.821 162.241 1.00 38.17  ? 231 LEU R N   1 
ATOM   7299 C CA  . LEU F 6 240 ? 122.765 132.836 161.392 1.00 38.17  ? 231 LEU R CA  1 
ATOM   7300 C C   . LEU F 6 240 ? 123.151 132.949 159.922 1.00 38.17  ? 231 LEU R C   1 
ATOM   7301 O O   . LEU F 6 240 ? 122.561 132.283 159.062 1.00 38.17  ? 231 LEU R O   1 
ATOM   7302 C CB  . LEU F 6 240 ? 121.854 133.991 161.800 1.00 38.17  ? 231 LEU R CB  1 
ATOM   7303 C CG  . LEU F 6 240 ? 120.388 133.878 161.382 1.00 38.17  ? 231 LEU R CG  1 
ATOM   7304 C CD1 . LEU F 6 240 ? 119.683 132.797 162.181 1.00 38.17  ? 231 LEU R CD1 1 
ATOM   7305 C CD2 . LEU F 6 240 ? 119.693 135.216 161.556 1.00 38.17  ? 231 LEU R CD2 1 
ATOM   7306 N N   . LEU F 6 241 ? 124.139 133.791 159.618 1.00 33.58  ? 232 LEU R N   1 
ATOM   7307 C CA  . LEU F 6 241 ? 124.591 133.932 158.240 1.00 33.58  ? 232 LEU R CA  1 
ATOM   7308 C C   . LEU F 6 241 ? 125.130 132.614 157.703 1.00 33.58  ? 232 LEU R C   1 
ATOM   7309 O O   . LEU F 6 241 ? 124.854 132.243 156.555 1.00 33.58  ? 232 LEU R O   1 
ATOM   7310 C CB  . LEU F 6 241 ? 125.656 135.024 158.155 1.00 33.58  ? 232 LEU R CB  1 
ATOM   7311 C CG  . LEU F 6 241 ? 126.144 135.410 156.758 1.00 33.58  ? 232 LEU R CG  1 
ATOM   7312 C CD1 . LEU F 6 241 ? 126.427 136.898 156.695 1.00 33.58  ? 232 LEU R CD1 1 
ATOM   7313 C CD2 . LEU F 6 241 ? 127.385 134.620 156.378 1.00 33.58  ? 232 LEU R CD2 1 
ATOM   7314 N N   . MET F 6 242 ? 125.758 131.838 158.586 1.00 33.92  ? 233 MET R N   1 
ATOM   7315 C CA  . MET F 6 242 ? 126.243 130.489 158.207 1.00 33.92  ? 233 MET R CA  1 
ATOM   7316 C C   . MET F 6 242 ? 125.023 129.616 157.906 1.00 33.92  ? 233 MET R C   1 
ATOM   7317 O O   . MET F 6 242 ? 124.964 129.052 156.800 1.00 33.92  ? 233 MET R O   1 
ATOM   7318 C CB  . MET F 6 242 ? 127.061 129.855 159.333 1.00 33.92  ? 233 MET R CB  1 
ATOM   7319 C CG  . MET F 6 242 ? 127.796 128.602 158.909 1.00 33.92  ? 233 MET R CG  1 
ATOM   7320 S SD  . MET F 6 242 ? 128.223 127.536 160.308 1.00 33.92  ? 233 MET R SD  1 
ATOM   7321 C CE  . MET F 6 242 ? 126.602 126.909 160.746 1.00 33.92  ? 233 MET R CE  1 
ATOM   7322 N N   . GLN F 6 243 ? 124.070 129.533 158.830 1.00 30.97  ? 234 GLN R N   1 
ATOM   7323 C CA  . GLN F 6 243 ? 122.878 128.670 158.664 1.00 30.97  ? 234 GLN R CA  1 
ATOM   7324 C C   . GLN F 6 243 ? 122.181 129.024 157.348 1.00 30.97  ? 234 GLN R C   1 
ATOM   7325 O O   . GLN F 6 243 ? 121.581 128.119 156.756 1.00 30.97  ? 234 GLN R O   1 
ATOM   7326 C CB  . GLN F 6 243 ? 121.936 128.835 159.853 1.00 30.97  ? 234 GLN R CB  1 
ATOM   7327 C CG  . GLN F 6 243 ? 122.543 128.421 161.184 1.00 30.97  ? 234 GLN R CG  1 
ATOM   7328 C CD  . GLN F 6 243 ? 122.642 126.924 161.331 1.00 30.97  ? 234 GLN R CD  1 
ATOM   7329 O OE1 . GLN F 6 243 ? 123.722 126.371 161.519 1.00 30.97  ? 234 GLN R OE1 1 
ATOM   7330 N NE2 . GLN F 6 243 ? 121.505 126.256 161.253 1.00 30.97  ? 234 GLN R NE2 1 
ATOM   7331 N N   . TYR F 6 244 ? 122.213 130.287 156.924 1.00 23.00  ? 235 TYR R N   1 
ATOM   7332 C CA  . TYR F 6 244 ? 121.502 130.700 155.721 1.00 23.00  ? 235 TYR R CA  1 
ATOM   7333 C C   . TYR F 6 244 ? 122.298 130.363 154.470 1.00 23.00  ? 235 TYR R C   1 
ATOM   7334 O O   . TYR F 6 244 ? 121.729 129.922 153.466 1.00 23.00  ? 235 TYR R O   1 
ATOM   7335 C CB  . TYR F 6 244 ? 121.198 132.194 155.765 1.00 23.00  ? 235 TYR R CB  1 
ATOM   7336 C CG  . TYR F 6 244 ? 120.589 132.699 154.479 1.00 23.00  ? 235 TYR R CG  1 
ATOM   7337 C CD1 . TYR F 6 244 ? 119.244 132.508 154.206 1.00 23.00  ? 235 TYR R CD1 1 
ATOM   7338 C CD2 . TYR F 6 244 ? 121.363 133.354 153.532 1.00 23.00  ? 235 TYR R CD2 1 
ATOM   7339 C CE1 . TYR F 6 244 ? 118.685 132.959 153.031 1.00 23.00  ? 235 TYR R CE1 1 
ATOM   7340 C CE2 . TYR F 6 244 ? 120.812 133.809 152.354 1.00 23.00  ? 235 TYR R CE2 1 
ATOM   7341 C CZ  . TYR F 6 244 ? 119.474 133.608 152.109 1.00 23.00  ? 235 TYR R CZ  1 
ATOM   7342 O OH  . TYR F 6 244 ? 118.919 134.060 150.937 1.00 23.00  ? 235 TYR R OH  1 
ATOM   7343 N N   . CYS F 6 245 ? 123.613 130.587 154.497 1.00 24.69  ? 236 CYS R N   1 
ATOM   7344 C CA  . CYS F 6 245 ? 124.426 130.287 153.324 1.00 24.69  ? 236 CYS R CA  1 
ATOM   7345 C C   . CYS F 6 245 ? 124.368 128.805 152.985 1.00 24.69  ? 236 CYS R C   1 
ATOM   7346 O O   . CYS F 6 245 ? 124.236 128.429 151.811 1.00 24.69  ? 236 CYS R O   1 
ATOM   7347 C CB  . CYS F 6 245 ? 125.867 130.729 153.558 1.00 24.69  ? 236 CYS R CB  1 
ATOM   7348 S SG  . CYS F 6 245 ? 126.157 132.478 153.230 1.00 24.69  ? 236 CYS R SG  1 
ATOM   7349 N N   . VAL F 6 246 ? 124.475 127.954 154.003 1.00 23.70  ? 237 VAL R N   1 
ATOM   7350 C CA  . VAL F 6 246 ? 124.419 126.480 153.802 1.00 23.70  ? 237 VAL R CA  1 
ATOM   7351 C C   . VAL F 6 246 ? 123.075 126.138 153.154 1.00 23.70  ? 237 VAL R C   1 
ATOM   7352 O O   . VAL F 6 246 ? 123.095 125.422 152.146 1.00 23.70  ? 237 VAL R O   1 
ATOM   7353 C CB  . VAL F 6 246 ? 124.634 125.712 155.116 1.00 23.70  ? 237 VAL R CB  1 
ATOM   7354 C CG1 . VAL F 6 246 ? 124.368 124.226 154.947 1.00 23.70  ? 237 VAL R CG1 1 
ATOM   7355 C CG2 . VAL F 6 246 ? 126.025 125.947 155.678 1.00 23.70  ? 237 VAL R CG2 1 
ATOM   7356 N N   . ALA F 6 247 ? 121.956 126.644 153.680 1.00 22.19  ? 238 ALA R N   1 
ATOM   7357 C CA  . ALA F 6 247 ? 120.640 126.317 153.141 1.00 22.19  ? 238 ALA R CA  1 
ATOM   7358 C C   . ALA F 6 247 ? 120.494 126.809 151.705 1.00 22.19  ? 238 ALA R C   1 
ATOM   7359 O O   . ALA F 6 247 ? 119.934 126.109 150.852 1.00 22.19  ? 238 ALA R O   1 
ATOM   7360 C CB  . ALA F 6 247 ? 119.547 126.913 154.025 1.00 22.19  ? 238 ALA R CB  1 
ATOM   7361 N N   . ALA F 6 248 ? 120.989 128.015 151.422 1.00 20.63  ? 239 ALA R N   1 
ATOM   7362 C CA  . ALA F 6 248 ? 120.889 128.557 150.072 1.00 20.63  ? 239 ALA R CA  1 
ATOM   7363 C C   . ALA F 6 248 ? 121.669 127.710 149.078 1.00 20.63  ? 239 ALA R C   1 
ATOM   7364 O O   . ALA F 6 248 ? 121.208 127.478 147.954 1.00 20.63  ? 239 ALA R O   1 
ATOM   7365 C CB  . ALA F 6 248 ? 121.393 129.999 150.049 1.00 20.63  ? 239 ALA R CB  1 
ATOM   7366 N N   . ASN F 6 249 ? 122.858 127.248 149.463 1.00 18.68  ? 240 ASN R N   1 
ATOM   7367 C CA  . ASN F 6 249 ? 123.635 126.406 148.560 1.00 18.68  ? 240 ASN R CA  1 
ATOM   7368 C C   . ASN F 6 249 ? 122.876 125.127 148.227 1.00 18.68  ? 240 ASN R C   1 
ATOM   7369 O O   . ASN F 6 249 ? 122.783 124.722 147.056 1.00 18.68  ? 240 ASN R O   1 
ATOM   7370 C CB  . ASN F 6 249 ? 124.993 126.087 149.188 1.00 18.68  ? 240 ASN R CB  1 
ATOM   7371 C CG  . ASN F 6 249 ? 125.826 125.138 148.346 1.00 18.68  ? 240 ASN R CG  1 
ATOM   7372 O OD1 . ASN F 6 249 ? 126.667 124.413 148.873 1.00 18.68  ? 240 ASN R OD1 1 
ATOM   7373 N ND2 . ASN F 6 249 ? 125.609 125.146 147.037 1.00 18.68  ? 240 ASN R ND2 1 
ATOM   7374 N N   . TYR F 6 250 ? 122.303 124.493 149.249 1.00 20.29  ? 241 TYR R N   1 
ATOM   7375 C CA  . TYR F 6 250 ? 121.543 123.234 149.074 1.00 20.29  ? 241 TYR R CA  1 
ATOM   7376 C C   . TYR F 6 250 ? 120.349 123.487 148.160 1.00 20.29  ? 241 TYR R C   1 
ATOM   7377 O O   . TYR F 6 250 ? 120.082 122.622 147.327 1.00 20.29  ? 241 TYR R O   1 
ATOM   7378 C CB  . TYR F 6 250 ? 121.074 122.675 150.414 1.00 20.29  ? 241 TYR R CB  1 
ATOM   7379 C CG  . TYR F 6 250 ? 122.094 121.842 151.146 1.00 20.29  ? 241 TYR R CG  1 
ATOM   7380 C CD1 . TYR F 6 250 ? 122.577 120.666 150.601 1.00 20.29  ? 241 TYR R CD1 1 
ATOM   7381 C CD2 . TYR F 6 250 ? 122.562 122.215 152.393 1.00 20.29  ? 241 TYR R CD2 1 
ATOM   7382 C CE1 . TYR F 6 250 ? 123.509 119.889 151.267 1.00 20.29  ? 241 TYR R CE1 1 
ATOM   7383 C CE2 . TYR F 6 250 ? 123.493 121.450 153.075 1.00 20.29  ? 241 TYR R CE2 1 
ATOM   7384 C CZ  . TYR F 6 250 ? 123.968 120.282 152.510 1.00 20.29  ? 241 TYR R CZ  1 
ATOM   7385 O OH  . TYR F 6 250 ? 124.886 119.525 153.177 1.00 20.29  ? 241 TYR R OH  1 
ATOM   7386 N N   . TYR F 6 251 ? 119.637 124.603 148.322 1.00 17.46  ? 242 TYR R N   1 
ATOM   7387 C CA  . TYR F 6 251 ? 118.461 124.872 147.503 1.00 17.46  ? 242 TYR R CA  1 
ATOM   7388 C C   . TYR F 6 251 ? 118.838 125.262 146.080 1.00 17.46  ? 242 TYR R C   1 
ATOM   7389 O O   . TYR F 6 251 ? 118.058 125.031 145.151 1.00 17.46  ? 242 TYR R O   1 
ATOM   7390 C CB  . TYR F 6 251 ? 117.599 125.949 148.153 1.00 17.46  ? 242 TYR R CB  1 
ATOM   7391 C CG  . TYR F 6 251 ? 116.462 125.363 148.949 1.00 17.46  ? 242 TYR R CG  1 
ATOM   7392 C CD1 . TYR F 6 251 ? 116.696 124.711 150.148 1.00 17.46  ? 242 TYR R CD1 1 
ATOM   7393 C CD2 . TYR F 6 251 ? 115.160 125.438 148.489 1.00 17.46  ? 242 TYR R CD2 1 
ATOM   7394 C CE1 . TYR F 6 251 ? 115.663 124.163 150.872 1.00 17.46  ? 242 TYR R CE1 1 
ATOM   7395 C CE2 . TYR F 6 251 ? 114.122 124.893 149.206 1.00 17.46  ? 242 TYR R CE2 1 
ATOM   7396 C CZ  . TYR F 6 251 ? 114.378 124.257 150.397 1.00 17.46  ? 242 TYR R CZ  1 
ATOM   7397 O OH  . TYR F 6 251 ? 113.344 123.710 151.115 1.00 17.46  ? 242 TYR R OH  1 
ATOM   7398 N N   . TRP F 6 252 ? 120.028 125.818 145.869 1.00 18.31  ? 243 TRP R N   1 
ATOM   7399 C CA  . TRP F 6 252 ? 120.429 126.103 144.496 1.00 18.31  ? 243 TRP R CA  1 
ATOM   7400 C C   . TRP F 6 252 ? 120.860 124.844 143.759 1.00 18.31  ? 243 TRP R C   1 
ATOM   7401 O O   . TRP F 6 252 ? 120.657 124.742 142.543 1.00 18.31  ? 243 TRP R O   1 
ATOM   7402 C CB  . TRP F 6 252 ? 121.535 127.153 144.466 1.00 18.31  ? 243 TRP R CB  1 
ATOM   7403 C CG  . TRP F 6 252 ? 120.962 128.508 144.285 1.00 18.31  ? 243 TRP R CG  1 
ATOM   7404 C CD1 . TRP F 6 252 ? 120.785 129.456 145.242 1.00 18.31  ? 243 TRP R CD1 1 
ATOM   7405 C CD2 . TRP F 6 252 ? 120.436 129.055 143.073 1.00 18.31  ? 243 TRP R CD2 1 
ATOM   7406 N NE1 . TRP F 6 252 ? 120.198 130.571 144.699 1.00 18.31  ? 243 TRP R NE1 1 
ATOM   7407 C CE2 . TRP F 6 252 ? 119.973 130.348 143.366 1.00 18.31  ? 243 TRP R CE2 1 
ATOM   7408 C CE3 . TRP F 6 252 ? 120.319 128.579 141.765 1.00 18.31  ? 243 TRP R CE3 1 
ATOM   7409 C CZ2 . TRP F 6 252 ? 119.405 131.174 142.401 1.00 18.31  ? 243 TRP R CZ2 1 
ATOM   7410 C CZ3 . TRP F 6 252 ? 119.757 129.399 140.809 1.00 18.31  ? 243 TRP R CZ3 1 
ATOM   7411 C CH2 . TRP F 6 252 ? 119.306 130.680 141.131 1.00 18.31  ? 243 TRP R CH2 1 
ATOM   7412 N N   . LEU F 6 253 ? 121.425 123.865 144.465 1.00 17.87  ? 244 LEU R N   1 
ATOM   7413 C CA  . LEU F 6 253 ? 121.578 122.549 143.845 1.00 17.87  ? 244 LEU R CA  1 
ATOM   7414 C C   . LEU F 6 253 ? 120.217 121.985 143.440 1.00 17.87  ? 244 LEU R C   1 
ATOM   7415 O O   . LEU F 6 253 ? 120.056 121.426 142.341 1.00 17.87  ? 244 LEU R O   1 
ATOM   7416 C CB  . LEU F 6 253 ? 122.297 121.595 144.797 1.00 17.87  ? 244 LEU R CB  1 
ATOM   7417 C CG  . LEU F 6 253 ? 123.780 121.886 145.023 1.00 17.87  ? 244 LEU R CG  1 
ATOM   7418 C CD1 . LEU F 6 253 ? 124.271 121.194 146.279 1.00 17.87  ? 244 LEU R CD1 1 
ATOM   7419 C CD2 . LEU F 6 253 ? 124.601 121.456 143.822 1.00 17.87  ? 244 LEU R CD2 1 
ATOM   7420 N N   . LEU F 6 254 ? 119.219 122.140 144.311 1.00 17.05  ? 245 LEU R N   1 
ATOM   7421 C CA  . LEU F 6 254 ? 117.868 121.708 143.960 1.00 17.05  ? 245 LEU R CA  1 
ATOM   7422 C C   . LEU F 6 254 ? 117.363 122.428 142.713 1.00 17.05  ? 245 LEU R C   1 
ATOM   7423 O O   . LEU F 6 254 ? 116.692 121.825 141.867 1.00 17.05  ? 245 LEU R O   1 
ATOM   7424 C CB  . LEU F 6 254 ? 116.917 121.942 145.132 1.00 17.05  ? 245 LEU R CB  1 
ATOM   7425 C CG  . LEU F 6 254 ? 115.422 121.886 144.815 1.00 17.05  ? 245 LEU R CG  1 
ATOM   7426 C CD1 . LEU F 6 254 ? 115.041 120.517 144.293 1.00 17.05  ? 245 LEU R CD1 1 
ATOM   7427 C CD2 . LEU F 6 254 ? 114.610 122.223 146.046 1.00 17.05  ? 245 LEU R CD2 1 
ATOM   7428 N N   . VAL F 6 255 ? 117.647 123.726 142.600 1.00 19.12  ? 246 VAL R N   1 
ATOM   7429 C CA  . VAL F 6 255 ? 117.216 124.485 141.427 1.00 19.12  ? 246 VAL R CA  1 
ATOM   7430 C C   . VAL F 6 255 ? 117.880 123.944 140.166 1.00 19.12  ? 246 VAL R C   1 
ATOM   7431 O O   . VAL F 6 255 ? 117.238 123.815 139.115 1.00 19.12  ? 246 VAL R O   1 
ATOM   7432 C CB  . VAL F 6 255 ? 117.513 125.981 141.623 1.00 19.12  ? 246 VAL R CB  1 
ATOM   7433 C CG1 . VAL F 6 255 ? 117.524 126.702 140.286 1.00 19.12  ? 246 VAL R CG1 1 
ATOM   7434 C CG2 . VAL F 6 255 ? 116.494 126.603 142.553 1.00 19.12  ? 246 VAL R CG2 1 
ATOM   7435 N N   . GLU F 6 256 ? 119.181 123.649 140.240 1.00 19.37  ? 247 GLU R N   1 
ATOM   7436 C CA  . GLU F 6 256 ? 119.858 123.012 139.113 1.00 19.37  ? 247 GLU R CA  1 
ATOM   7437 C C   . GLU F 6 256 ? 119.085 121.782 138.663 1.00 19.37  ? 247 GLU R C   1 
ATOM   7438 O O   . GLU F 6 256 ? 118.751 121.623 137.478 1.00 19.37  ? 247 GLU R O   1 
ATOM   7439 C CB  . GLU F 6 256 ? 121.272 122.591 139.515 1.00 19.37  ? 247 GLU R CB  1 
ATOM   7440 C CG  . GLU F 6 256 ? 122.259 123.695 139.841 1.00 19.37  ? 247 GLU R CG  1 
ATOM   7441 C CD  . GLU F 6 256 ? 122.623 124.546 138.650 1.00 19.37  ? 247 GLU R CD  1 
ATOM   7442 O OE1 . GLU F 6 256 ? 122.636 124.021 137.518 1.00 19.37  ? 247 GLU R OE1 1 
ATOM   7443 O OE2 . GLU F 6 256 ? 122.950 125.734 138.856 1.00 19.37  ? 247 GLU R OE2 1 
ATOM   7444 N N   . GLY F 6 257 ? 118.784 120.904 139.620 1.00 16.64  ? 248 GLY R N   1 
ATOM   7445 C CA  . GLY F 6 257 ? 118.118 119.658 139.276 1.00 16.64  ? 248 GLY R CA  1 
ATOM   7446 C C   . GLY F 6 257 ? 116.755 119.883 138.651 1.00 16.64  ? 248 GLY R C   1 
ATOM   7447 O O   . GLY F 6 257 ? 116.402 119.253 137.649 1.00 16.64  ? 248 GLY R O   1 
ATOM   7448 N N   . VAL F 6 258 ? 115.972 120.790 139.234 1.00 17.04  ? 249 VAL R N   1 
ATOM   7449 C CA  . VAL F 6 258 ? 114.617 121.024 138.740 1.00 17.04  ? 249 VAL R CA  1 
ATOM   7450 C C   . VAL F 6 258 ? 114.652 121.584 137.326 1.00 17.04  ? 249 VAL R C   1 
ATOM   7451 O O   . VAL F 6 258 ? 113.862 121.179 136.464 1.00 17.04  ? 249 VAL R O   1 
ATOM   7452 C CB  . VAL F 6 258 ? 113.852 121.956 139.694 1.00 17.04  ? 249 VAL R CB  1 
ATOM   7453 C CG1 . VAL F 6 258 ? 112.571 122.443 139.040 1.00 17.04  ? 249 VAL R CG1 1 
ATOM   7454 C CG2 . VAL F 6 258 ? 113.550 121.242 140.998 1.00 17.04  ? 249 VAL R CG2 1 
ATOM   7455 N N   . TYR F 6 259 ? 115.547 122.537 137.062 1.00 18.87  ? 250 TYR R N   1 
ATOM   7456 C CA  . TYR F 6 259 ? 115.609 123.107 135.721 1.00 18.87  ? 250 TYR R CA  1 
ATOM   7457 C C   . TYR F 6 259 ? 116.000 122.050 134.697 1.00 18.87  ? 250 TYR R C   1 
ATOM   7458 O O   . TYR F 6 259 ? 115.407 121.975 133.611 1.00 18.87  ? 250 TYR R O   1 
ATOM   7459 C CB  . TYR F 6 259 ? 116.589 124.274 135.675 1.00 18.87  ? 250 TYR R CB  1 
ATOM   7460 C CG  . TYR F 6 259 ? 116.820 124.791 134.275 1.00 18.87  ? 250 TYR R CG  1 
ATOM   7461 C CD1 . TYR F 6 259 ? 115.817 125.459 133.591 1.00 18.87  ? 250 TYR R CD1 1 
ATOM   7462 C CD2 . TYR F 6 259 ? 118.034 124.605 133.634 1.00 18.87  ? 250 TYR R CD2 1 
ATOM   7463 C CE1 . TYR F 6 259 ? 116.016 125.931 132.315 1.00 18.87  ? 250 TYR R CE1 1 
ATOM   7464 C CE2 . TYR F 6 259 ? 118.243 125.074 132.356 1.00 18.87  ? 250 TYR R CE2 1 
ATOM   7465 C CZ  . TYR F 6 259 ? 117.231 125.737 131.702 1.00 18.87  ? 250 TYR R CZ  1 
ATOM   7466 O OH  . TYR F 6 259 ? 117.433 126.206 130.426 1.00 18.87  ? 250 TYR R OH  1 
ATOM   7467 N N   . LEU F 6 260 ? 116.996 121.219 135.020 1.00 17.72  ? 251 LEU R N   1 
ATOM   7468 C CA  . LEU F 6 260 ? 117.375 120.170 134.078 1.00 17.72  ? 251 LEU R CA  1 
ATOM   7469 C C   . LEU F 6 260 ? 116.210 119.222 133.825 1.00 17.72  ? 251 LEU R C   1 
ATOM   7470 O O   . LEU F 6 260 ? 115.944 118.839 132.678 1.00 17.72  ? 251 LEU R O   1 
ATOM   7471 C CB  . LEU F 6 260 ? 118.592 119.403 134.597 1.00 17.72  ? 251 LEU R CB  1 
ATOM   7472 C CG  . LEU F 6 260 ? 118.992 118.164 133.791 1.00 17.72  ? 251 LEU R CG  1 
ATOM   7473 C CD1 . LEU F 6 260 ? 119.088 118.487 132.311 1.00 17.72  ? 251 LEU R CD1 1 
ATOM   7474 C CD2 . LEU F 6 260 ? 120.309 117.609 134.293 1.00 17.72  ? 251 LEU R CD2 1 
ATOM   7475 N N   . TYR F 6 261 ? 115.494 118.840 134.884 1.00 16.27  ? 252 TYR R N   1 
ATOM   7476 C CA  . TYR F 6 261 ? 114.364 117.938 134.706 1.00 16.27  ? 252 TYR R CA  1 
ATOM   7477 C C   . TYR F 6 261 ? 113.305 118.558 133.809 1.00 16.27  ? 252 TYR R C   1 
ATOM   7478 O O   . TYR F 6 261 ? 112.749 117.883 132.936 1.00 16.27  ? 252 TYR R O   1 
ATOM   7479 C CB  . TYR F 6 261 ? 113.762 117.573 136.060 1.00 16.27  ? 252 TYR R CB  1 
ATOM   7480 C CG  . TYR F 6 261 ? 112.478 116.789 135.951 1.00 16.27  ? 252 TYR R CG  1 
ATOM   7481 C CD1 . TYR F 6 261 ? 112.496 115.418 135.744 1.00 16.27  ? 252 TYR R CD1 1 
ATOM   7482 C CD2 . TYR F 6 261 ? 111.247 117.417 136.055 1.00 16.27  ? 252 TYR R CD2 1 
ATOM   7483 C CE1 . TYR F 6 261 ? 111.324 114.697 135.645 1.00 16.27  ? 252 TYR R CE1 1 
ATOM   7484 C CE2 . TYR F 6 261 ? 110.072 116.705 135.957 1.00 16.27  ? 252 TYR R CE2 1 
ATOM   7485 C CZ  . TYR F 6 261 ? 110.116 115.345 135.752 1.00 16.27  ? 252 TYR R CZ  1 
ATOM   7486 O OH  . TYR F 6 261 ? 108.945 114.631 135.652 1.00 16.27  ? 252 TYR R OH  1 
ATOM   7487 N N   . THR F 6 262 ? 113.006 119.842 134.010 1.00 19.57  ? 253 THR R N   1 
ATOM   7488 C CA  . THR F 6 262 ? 112.015 120.495 133.161 1.00 19.57  ? 253 THR R CA  1 
ATOM   7489 C C   . THR F 6 262 ? 112.460 120.498 131.706 1.00 19.57  ? 253 THR R C   1 
ATOM   7490 O O   . THR F 6 262 ? 111.654 120.241 130.805 1.00 19.57  ? 253 THR R O   1 
ATOM   7491 C CB  . THR F 6 262 ? 111.758 121.924 133.636 1.00 19.57  ? 253 THR R CB  1 
ATOM   7492 O OG1 . THR F 6 262 ? 113.006 122.594 133.846 1.00 19.57  ? 253 THR R OG1 1 
ATOM   7493 C CG2 . THR F 6 262 ? 110.955 121.921 134.925 1.00 19.57  ? 253 THR R CG2 1 
ATOM   7494 N N   . LEU F 6 263 ? 113.738 120.783 131.455 1.00 19.48  ? 254 LEU R N   1 
ATOM   7495 C CA  . LEU F 6 263 ? 114.217 120.767 130.074 1.00 19.48  ? 254 LEU R CA  1 
ATOM   7496 C C   . LEU F 6 263 ? 114.064 119.387 129.449 1.00 19.48  ? 254 LEU R C   1 
ATOM   7497 O O   . LEU F 6 263 ? 113.641 119.267 128.295 1.00 19.48  ? 254 LEU R O   1 
ATOM   7498 C CB  . LEU F 6 263 ? 115.676 121.214 130.001 1.00 19.48  ? 254 LEU R CB  1 
ATOM   7499 C CG  . LEU F 6 263 ? 115.950 122.709 129.860 1.00 19.48  ? 254 LEU R CG  1 
ATOM   7500 C CD1 . LEU F 6 263 ? 117.443 122.948 129.769 1.00 19.48  ? 254 LEU R CD1 1 
ATOM   7501 C CD2 . LEU F 6 263 ? 115.249 123.282 128.645 1.00 19.48  ? 254 LEU R CD2 1 
ATOM   7502 N N   . LEU F 6 264 ? 114.406 118.332 130.189 1.00 21.02  ? 255 LEU R N   1 
ATOM   7503 C CA  . LEU F 6 264 ? 114.368 116.991 129.614 1.00 21.02  ? 255 LEU R CA  1 
ATOM   7504 C C   . LEU F 6 264 ? 112.971 116.383 129.584 1.00 21.02  ? 255 LEU R C   1 
ATOM   7505 O O   . LEU F 6 264 ? 112.797 115.314 128.993 1.00 21.02  ? 255 LEU R O   1 
ATOM   7506 C CB  . LEU F 6 264 ? 115.303 116.054 130.381 1.00 21.02  ? 255 LEU R CB  1 
ATOM   7507 C CG  . LEU F 6 264 ? 116.805 116.188 130.123 1.00 21.02  ? 255 LEU R CG  1 
ATOM   7508 C CD1 . LEU F 6 264 ? 117.520 114.971 130.671 1.00 21.02  ? 255 LEU R CD1 1 
ATOM   7509 C CD2 . LEU F 6 264 ? 117.120 116.361 128.647 1.00 21.02  ? 255 LEU R CD2 1 
ATOM   7510 N N   . ALA F 6 265 ? 111.980 117.021 130.198 1.00 21.94  ? 256 ALA R N   1 
ATOM   7511 C CA  . ALA F 6 265 ? 110.605 116.547 130.123 1.00 21.94  ? 256 ALA R CA  1 
ATOM   7512 C C   . ALA F 6 265 ? 109.890 117.027 128.869 1.00 21.94  ? 256 ALA R C   1 
ATOM   7513 O O   . ALA F 6 265 ? 108.678 116.824 128.749 1.00 21.94  ? 256 ALA R O   1 
ATOM   7514 C CB  . ALA F 6 265 ? 109.824 116.991 131.361 1.00 21.94  ? 256 ALA R CB  1 
ATOM   7515 N N   . PHE F 6 266 ? 110.612 117.654 127.943 1.00 25.52  ? 257 PHE R N   1 
ATOM   7516 C CA  . PHE F 6 266 ? 110.044 118.197 126.711 1.00 25.52  ? 257 PHE R CA  1 
ATOM   7517 C C   . PHE F 6 266 ? 108.813 119.052 127.011 1.00 25.52  ? 257 PHE R C   1 
ATOM   7518 O O   . PHE F 6 266 ? 107.694 118.769 126.578 1.00 25.52  ? 257 PHE R O   1 
ATOM   7519 C CB  . PHE F 6 266 ? 109.706 117.079 125.721 1.00 25.52  ? 257 PHE R CB  1 
ATOM   7520 C CG  . PHE F 6 266 ? 109.372 117.571 124.337 1.00 25.52  ? 257 PHE R CG  1 
ATOM   7521 C CD1 . PHE F 6 266 ? 110.008 118.681 123.803 1.00 25.52  ? 257 PHE R CD1 1 
ATOM   7522 C CD2 . PHE F 6 266 ? 108.409 116.931 123.577 1.00 25.52  ? 257 PHE R CD2 1 
ATOM   7523 C CE1 . PHE F 6 266 ? 109.697 119.132 122.536 1.00 25.52  ? 257 PHE R CE1 1 
ATOM   7524 C CE2 . PHE F 6 266 ? 108.093 117.381 122.308 1.00 25.52  ? 257 PHE R CE2 1 
ATOM   7525 C CZ  . PHE F 6 266 ? 108.739 118.483 121.789 1.00 25.52  ? 257 PHE R CZ  1 
ATOM   7526 N N   . SER F 6 267 ? 109.045 120.117 127.776 1.00 45.67  ? 258 SER R N   1 
ATOM   7527 C CA  . SER F 6 267 ? 108.013 121.090 128.093 1.00 45.67  ? 258 SER R CA  1 
ATOM   7528 C C   . SER F 6 267 ? 108.593 122.485 127.915 1.00 45.67  ? 258 SER R C   1 
ATOM   7529 O O   . SER F 6 267 ? 109.798 122.696 128.072 1.00 45.67  ? 258 SER R O   1 
ATOM   7530 C CB  . SER F 6 267 ? 107.483 120.908 129.520 1.00 45.67  ? 258 SER R CB  1 
ATOM   7531 O OG  . SER F 6 267 ? 106.384 121.765 129.766 1.00 45.67  ? 258 SER R OG  1 
ATOM   7532 N N   . VAL F 6 268 ? 107.723 123.436 127.582 1.00 55.30  ? 259 VAL R N   1 
ATOM   7533 C CA  . VAL F 6 268 ? 108.125 124.809 127.301 1.00 55.30  ? 259 VAL R CA  1 
ATOM   7534 C C   . VAL F 6 268 ? 107.315 125.749 128.182 1.00 55.30  ? 259 VAL R C   1 
ATOM   7535 O O   . VAL F 6 268 ? 106.103 125.572 128.349 1.00 55.30  ? 259 VAL R O   1 
ATOM   7536 C CB  . VAL F 6 268 ? 107.942 125.163 125.811 1.00 55.30  ? 259 VAL R CB  1 
ATOM   7537 C CG1 . VAL F 6 268 ? 106.467 125.349 125.483 1.00 55.30  ? 259 VAL R CG1 1 
ATOM   7538 C CG2 . VAL F 6 268 ? 108.740 126.410 125.460 1.00 55.30  ? 259 VAL R CG2 1 
ATOM   7539 N N   . PHE F 6 269 ? 107.991 126.746 128.749 1.00 60.57  ? 260 PHE R N   1 
ATOM   7540 C CA  . PHE F 6 269 ? 107.360 127.714 129.631 1.00 60.57  ? 260 PHE R CA  1 
ATOM   7541 C C   . PHE F 6 269 ? 107.937 129.095 129.350 1.00 60.57  ? 260 PHE R C   1 
ATOM   7542 O O   . PHE F 6 269 ? 109.021 129.230 128.778 1.00 60.57  ? 260 PHE R O   1 
ATOM   7543 C CB  . PHE F 6 269 ? 107.567 127.347 131.105 1.00 60.57  ? 260 PHE R CB  1 
ATOM   7544 C CG  . PHE F 6 269 ? 106.867 126.088 131.519 1.00 60.57  ? 260 PHE R CG  1 
ATOM   7545 C CD1 . PHE F 6 269 ? 105.518 126.095 131.823 1.00 60.57  ? 260 PHE R CD1 1 
ATOM   7546 C CD2 . PHE F 6 269 ? 107.562 124.894 131.603 1.00 60.57  ? 260 PHE R CD2 1 
ATOM   7547 C CE1 . PHE F 6 269 ? 104.873 124.934 132.205 1.00 60.57  ? 260 PHE R CE1 1 
ATOM   7548 C CE2 . PHE F 6 269 ? 106.924 123.730 131.984 1.00 60.57  ? 260 PHE R CE2 1 
ATOM   7549 C CZ  . PHE F 6 269 ? 105.577 123.751 132.285 1.00 60.57  ? 260 PHE R CZ  1 
ATOM   7550 N N   . SER F 6 270 ? 107.194 130.121 129.756 1.00 65.57  ? 261 SER R N   1 
ATOM   7551 C CA  . SER F 6 270 ? 107.666 131.490 129.592 1.00 65.57  ? 261 SER R CA  1 
ATOM   7552 C C   . SER F 6 270 ? 109.005 131.667 130.294 1.00 65.57  ? 261 SER R C   1 
ATOM   7553 O O   . SER F 6 270 ? 109.165 131.291 131.458 1.00 65.57  ? 261 SER R O   1 
ATOM   7554 C CB  . SER F 6 270 ? 106.637 132.472 130.150 1.00 65.57  ? 261 SER R CB  1 
ATOM   7555 O OG  . SER F 6 270 ? 106.323 132.167 131.496 1.00 65.57  ? 261 SER R OG  1 
ATOM   7556 N N   . GLU F 6 271 ? 109.969 132.251 129.582 1.00 62.67  ? 262 GLU R N   1 
ATOM   7557 C CA  . GLU F 6 271 ? 111.341 132.285 130.083 1.00 62.67  ? 262 GLU R CA  1 
ATOM   7558 C C   . GLU F 6 271 ? 111.493 133.277 131.231 1.00 62.67  ? 262 GLU R C   1 
ATOM   7559 O O   . GLU F 6 271 ? 112.096 132.959 132.261 1.00 62.67  ? 262 GLU R O   1 
ATOM   7560 C CB  . GLU F 6 271 ? 112.312 132.622 128.948 1.00 62.67  ? 262 GLU R CB  1 
ATOM   7561 N N   . GLN F 6 272 ? 110.954 134.488 131.074 1.00 62.97  ? 263 GLN R N   1 
ATOM   7562 C CA  . GLN F 6 272 ? 111.159 135.523 132.082 1.00 62.97  ? 263 GLN R CA  1 
ATOM   7563 C C   . GLN F 6 272 ? 110.497 135.144 133.402 1.00 62.97  ? 263 GLN R C   1 
ATOM   7564 O O   . GLN F 6 272 ? 111.119 135.220 134.471 1.00 62.97  ? 263 GLN R O   1 
ATOM   7565 C CB  . GLN F 6 272 ? 110.616 136.858 131.569 1.00 62.97  ? 263 GLN R CB  1 
ATOM   7566 C CG  . GLN F 6 272 ? 111.072 138.071 132.369 1.00 62.97  ? 263 GLN R CG  1 
ATOM   7567 C CD  . GLN F 6 272 ? 110.234 138.310 133.611 1.00 62.97  ? 263 GLN R CD  1 
ATOM   7568 O OE1 . GLN F 6 272 ? 109.162 137.727 133.775 1.00 62.97  ? 263 GLN R OE1 1 
ATOM   7569 N NE2 . GLN F 6 272 ? 110.720 139.176 134.493 1.00 62.97  ? 263 GLN R NE2 1 
ATOM   7570 N N   . TRP F 6 273 ? 109.227 134.743 133.345 1.00 59.66  ? 264 TRP R N   1 
ATOM   7571 C CA  . TRP F 6 273 ? 108.513 134.368 134.559 1.00 59.66  ? 264 TRP R CA  1 
ATOM   7572 C C   . TRP F 6 273 ? 109.177 133.178 135.235 1.00 59.66  ? 264 TRP R C   1 
ATOM   7573 O O   . TRP F 6 273 ? 109.335 133.156 136.463 1.00 59.66  ? 264 TRP R O   1 
ATOM   7574 C CB  . TRP F 6 273 ? 107.054 134.059 134.221 1.00 59.66  ? 264 TRP R CB  1 
ATOM   7575 C CG  . TRP F 6 273 ? 106.273 133.458 135.347 1.00 59.66  ? 264 TRP R CG  1 
ATOM   7576 C CD1 . TRP F 6 273 ? 105.997 134.034 136.552 1.00 59.66  ? 264 TRP R CD1 1 
ATOM   7577 C CD2 . TRP F 6 273 ? 105.656 132.167 135.367 1.00 59.66  ? 264 TRP R CD2 1 
ATOM   7578 N NE1 . TRP F 6 273 ? 105.249 133.178 137.324 1.00 59.66  ? 264 TRP R NE1 1 
ATOM   7579 C CE2 . TRP F 6 273 ? 105.026 132.025 136.618 1.00 59.66  ? 264 TRP R CE2 1 
ATOM   7580 C CE3 . TRP F 6 273 ? 105.575 131.115 134.449 1.00 59.66  ? 264 TRP R CE3 1 
ATOM   7581 C CZ2 . TRP F 6 273 ? 104.326 130.875 136.976 1.00 59.66  ? 264 TRP R CZ2 1 
ATOM   7582 C CZ3 . TRP F 6 273 ? 104.880 129.975 134.805 1.00 59.66  ? 264 TRP R CZ3 1 
ATOM   7583 C CH2 . TRP F 6 273 ? 104.265 129.863 136.058 1.00 59.66  ? 264 TRP R CH2 1 
ATOM   7584 N N   . ILE F 6 274 ? 109.585 132.181 134.448 1.00 50.94  ? 265 ILE R N   1 
ATOM   7585 C CA  . ILE F 6 274 ? 110.226 131.001 135.016 1.00 50.94  ? 265 ILE R CA  1 
ATOM   7586 C C   . ILE F 6 274 ? 111.539 131.374 135.690 1.00 50.94  ? 265 ILE R C   1 
ATOM   7587 O O   . ILE F 6 274 ? 111.846 130.891 136.784 1.00 50.94  ? 265 ILE R O   1 
ATOM   7588 C CB  . ILE F 6 274 ? 110.429 129.930 133.927 1.00 50.94  ? 265 ILE R CB  1 
ATOM   7589 C CG1 . ILE F 6 274 ? 109.099 129.252 133.585 1.00 50.94  ? 265 ILE R CG1 1 
ATOM   7590 C CG2 . ILE F 6 274 ? 111.455 128.903 134.369 1.00 50.94  ? 265 ILE R CG2 1 
ATOM   7591 C CD1 . ILE F 6 274 ? 108.497 128.422 134.713 1.00 50.94  ? 265 ILE R CD1 1 
ATOM   7592 N N   . PHE F 6 275 ? 112.342 132.223 135.048 1.00 42.94  ? 266 PHE R N   1 
ATOM   7593 C CA  . PHE F 6 275 ? 113.620 132.601 135.646 1.00 42.94  ? 266 PHE R CA  1 
ATOM   7594 C C   . PHE F 6 275 ? 113.417 133.394 136.930 1.00 42.94  ? 266 PHE R C   1 
ATOM   7595 O O   . PHE F 6 275 ? 114.143 133.191 137.913 1.00 42.94  ? 266 PHE R O   1 
ATOM   7596 C CB  . PHE F 6 275 ? 114.456 133.403 134.652 1.00 42.94  ? 266 PHE R CB  1 
ATOM   7597 C CG  . PHE F 6 275 ? 115.835 133.722 135.150 1.00 42.94  ? 266 PHE R CG  1 
ATOM   7598 C CD1 . PHE F 6 275 ? 116.701 132.708 135.521 1.00 42.94  ? 266 PHE R CD1 1 
ATOM   7599 C CD2 . PHE F 6 275 ? 116.267 135.033 135.247 1.00 42.94  ? 266 PHE R CD2 1 
ATOM   7600 C CE1 . PHE F 6 275 ? 117.969 132.994 135.981 1.00 42.94  ? 266 PHE R CE1 1 
ATOM   7601 C CE2 . PHE F 6 275 ? 117.538 135.325 135.706 1.00 42.94  ? 266 PHE R CE2 1 
ATOM   7602 C CZ  . PHE F 6 275 ? 118.389 134.304 136.074 1.00 42.94  ? 266 PHE R CZ  1 
ATOM   7603 N N   . ARG F 6 276 ? 112.445 134.308 136.942 1.00 47.30  ? 267 ARG R N   1 
ATOM   7604 C CA  . ARG F 6 276 ? 112.160 135.042 138.169 1.00 47.30  ? 267 ARG R CA  1 
ATOM   7605 C C   . ARG F 6 276 ? 111.722 134.094 139.278 1.00 47.30  ? 267 ARG R C   1 
ATOM   7606 O O   . ARG F 6 276 ? 112.159 134.223 140.430 1.00 47.30  ? 267 ARG R O   1 
ATOM   7607 C CB  . ARG F 6 276 ? 111.089 136.100 137.910 1.00 47.30  ? 267 ARG R CB  1 
ATOM   7608 C CG  . ARG F 6 276 ? 111.565 137.263 137.050 1.00 47.30  ? 267 ARG R CG  1 
ATOM   7609 C CD  . ARG F 6 276 ? 112.350 138.287 137.856 1.00 47.30  ? 267 ARG R CD  1 
ATOM   7610 N NE  . ARG F 6 276 ? 113.791 138.110 137.724 1.00 47.30  ? 267 ARG R NE  1 
ATOM   7611 C CZ  . ARG F 6 276 ? 114.696 138.740 138.461 1.00 47.30  ? 267 ARG R CZ  1 
ATOM   7612 N NH1 . ARG F 6 276 ? 114.344 139.597 139.406 1.00 47.30  ? 267 ARG R NH1 1 
ATOM   7613 N NH2 . ARG F 6 276 ? 115.987 138.504 138.245 1.00 47.30  ? 267 ARG R NH2 1 
ATOM   7614 N N   . LEU F 6 277 ? 110.867 133.124 138.945 1.00 35.88  ? 268 LEU R N   1 
ATOM   7615 C CA  . LEU F 6 277 ? 110.426 132.158 139.943 1.00 35.88  ? 268 LEU R CA  1 
ATOM   7616 C C   . LEU F 6 277 ? 111.597 131.336 140.467 1.00 35.88  ? 268 LEU R C   1 
ATOM   7617 O O   . LEU F 6 277 ? 111.668 131.038 141.663 1.00 35.88  ? 268 LEU R O   1 
ATOM   7618 C CB  . LEU F 6 277 ? 109.356 131.244 139.350 1.00 35.88  ? 268 LEU R CB  1 
ATOM   7619 C CG  . LEU F 6 277 ? 108.867 130.119 140.264 1.00 35.88  ? 268 LEU R CG  1 
ATOM   7620 C CD1 . LEU F 6 277 ? 108.436 130.667 141.611 1.00 35.88  ? 268 LEU R CD1 1 
ATOM   7621 C CD2 . LEU F 6 277 ? 107.730 129.361 139.608 1.00 35.88  ? 268 LEU R CD2 1 
ATOM   7622 N N   . TYR F 6 278 ? 112.519 130.949 139.585 1.00 28.74  ? 269 TYR R N   1 
ATOM   7623 C CA  . TYR F 6 278 ? 113.676 130.177 140.025 1.00 28.74  ? 269 TYR R CA  1 
ATOM   7624 C C   . TYR F 6 278 ? 114.563 130.995 140.951 1.00 28.74  ? 269 TYR R C   1 
ATOM   7625 O O   . TYR F 6 278 ? 115.055 130.478 141.959 1.00 28.74  ? 269 TYR R O   1 
ATOM   7626 C CB  . TYR F 6 278 ? 114.476 129.680 138.821 1.00 28.74  ? 269 TYR R CB  1 
ATOM   7627 C CG  . TYR F 6 278 ? 113.825 128.549 138.051 1.00 28.74  ? 269 TYR R CG  1 
ATOM   7628 C CD1 . TYR F 6 278 ? 112.837 127.759 138.625 1.00 28.74  ? 269 TYR R CD1 1 
ATOM   7629 C CD2 . TYR F 6 278 ? 114.206 128.269 136.747 1.00 28.74  ? 269 TYR R CD2 1 
ATOM   7630 C CE1 . TYR F 6 278 ? 112.246 126.732 137.923 1.00 28.74  ? 269 TYR R CE1 1 
ATOM   7631 C CE2 . TYR F 6 278 ? 113.621 127.243 136.039 1.00 28.74  ? 269 TYR R CE2 1 
ATOM   7632 C CZ  . TYR F 6 278 ? 112.641 126.478 136.631 1.00 28.74  ? 269 TYR R CZ  1 
ATOM   7633 O OH  . TYR F 6 278 ? 112.053 125.452 135.930 1.00 28.74  ? 269 TYR R OH  1 
ATOM   7634 N N   . VAL F 6 279 ? 114.792 132.267 140.626 1.00 28.75  ? 270 VAL R N   1 
ATOM   7635 C CA  . VAL F 6 279 ? 115.594 133.106 141.513 1.00 28.75  ? 270 VAL R CA  1 
ATOM   7636 C C   . VAL F 6 279 ? 114.925 133.217 142.876 1.00 28.75  ? 270 VAL R C   1 
ATOM   7637 O O   . VAL F 6 279 ? 115.583 133.119 143.922 1.00 28.75  ? 270 VAL R O   1 
ATOM   7638 C CB  . VAL F 6 279 ? 115.824 134.491 140.883 1.00 28.75  ? 270 VAL R CB  1 
ATOM   7639 C CG1 . VAL F 6 279 ? 116.358 135.462 141.922 1.00 28.75  ? 270 VAL R CG1 1 
ATOM   7640 C CG2 . VAL F 6 279 ? 116.778 134.385 139.705 1.00 28.75  ? 270 VAL R CG2 1 
ATOM   7641 N N   . SER F 6 280 ? 113.606 133.419 142.886 1.00 25.41  ? 271 SER R N   1 
ATOM   7642 C CA  . SER F 6 280 ? 112.884 133.506 144.151 1.00 25.41  ? 271 SER R CA  1 
ATOM   7643 C C   . SER F 6 280 ? 113.004 132.212 144.945 1.00 25.41  ? 271 SER R C   1 
ATOM   7644 O O   . SER F 6 280 ? 113.209 132.239 146.163 1.00 25.41  ? 271 SER R O   1 
ATOM   7645 C CB  . SER F 6 280 ? 111.415 133.835 143.894 1.00 25.41  ? 271 SER R CB  1 
ATOM   7646 O OG  . SER F 6 280 ? 110.643 133.650 145.066 1.00 25.41  ? 271 SER R OG  1 
ATOM   7647 N N   . ILE F 6 281 ? 112.871 131.068 144.274 1.00 22.50  ? 272 ILE R N   1 
ATOM   7648 C CA  . ILE F 6 281 ? 112.980 129.785 144.961 1.00 22.50  ? 272 ILE R CA  1 
ATOM   7649 C C   . ILE F 6 281 ? 114.374 129.611 145.545 1.00 22.50  ? 272 ILE R C   1 
ATOM   7650 O O   . ILE F 6 281 ? 114.537 129.147 146.679 1.00 22.50  ? 272 ILE R O   1 
ATOM   7651 C CB  . ILE F 6 281 ? 112.626 128.633 144.001 1.00 22.50  ? 272 ILE R CB  1 
ATOM   7652 C CG1 . ILE F 6 281 ? 111.122 128.614 143.706 1.00 22.50  ? 272 ILE R CG1 1 
ATOM   7653 C CG2 . ILE F 6 281 ? 113.080 127.301 144.575 1.00 22.50  ? 272 ILE R CG2 1 
ATOM   7654 C CD1 . ILE F 6 281 ? 110.251 128.239 144.894 1.00 22.50  ? 272 ILE R CD1 1 
ATOM   7655 N N   . GLY F 6 282 ? 115.397 129.976 144.782 1.00 19.89  ? 273 GLY R N   1 
ATOM   7656 C CA  . GLY F 6 282 ? 116.765 129.798 145.216 1.00 19.89  ? 273 GLY R CA  1 
ATOM   7657 C C   . GLY F 6 282 ? 117.140 130.667 146.396 1.00 19.89  ? 273 GLY R C   1 
ATOM   7658 O O   . GLY F 6 282 ? 117.476 130.153 147.465 1.00 19.89  ? 273 GLY R O   1 
ATOM   7659 N N   . TRP F 6 283 ? 117.087 131.987 146.221 1.00 17.12  ? 274 TRP R N   1 
ATOM   7660 C CA  . TRP F 6 283 ? 117.585 132.896 147.245 1.00 17.12  ? 274 TRP R CA  1 
ATOM   7661 C C   . TRP F 6 283 ? 116.543 133.270 148.291 1.00 17.12  ? 274 TRP R C   1 
ATOM   7662 O O   . TRP F 6 283 ? 116.900 133.900 149.291 1.00 17.12  ? 274 TRP R O   1 
ATOM   7663 C CB  . TRP F 6 283 ? 118.117 134.175 146.595 1.00 17.12  ? 274 TRP R CB  1 
ATOM   7664 C CG  . TRP F 6 283 ? 119.406 133.986 145.865 1.00 17.12  ? 274 TRP R CG  1 
ATOM   7665 C CD1 . TRP F 6 283 ? 119.620 134.154 144.531 1.00 17.12  ? 274 TRP R CD1 1 
ATOM   7666 C CD2 . TRP F 6 283 ? 120.663 133.594 146.426 1.00 17.12  ? 274 TRP R CD2 1 
ATOM   7667 N NE1 . TRP F 6 283 ? 120.931 133.890 144.224 1.00 17.12  ? 274 TRP R NE1 1 
ATOM   7668 C CE2 . TRP F 6 283 ? 121.593 133.544 145.372 1.00 17.12  ? 274 TRP R CE2 1 
ATOM   7669 C CE3 . TRP F 6 283 ? 121.091 133.279 147.717 1.00 17.12  ? 274 TRP R CE3 1 
ATOM   7670 C CZ2 . TRP F 6 283 ? 122.924 133.194 145.569 1.00 17.12  ? 274 TRP R CZ2 1 
ATOM   7671 C CZ3 . TRP F 6 283 ? 122.412 132.931 147.911 1.00 17.12  ? 274 TRP R CZ3 1 
ATOM   7672 C CH2 . TRP F 6 283 ? 123.313 132.891 146.842 1.00 17.12  ? 274 TRP R CH2 1 
ATOM   7673 N N   . GLY F 6 284 ? 115.279 132.900 148.100 1.00 20.08  ? 275 GLY R N   1 
ATOM   7674 C CA  . GLY F 6 284 ? 114.219 133.378 148.967 1.00 20.08  ? 275 GLY R CA  1 
ATOM   7675 C C   . GLY F 6 284 ? 113.653 132.356 149.930 1.00 20.08  ? 275 GLY R C   1 
ATOM   7676 O O   . GLY F 6 284 ? 113.345 132.689 151.077 1.00 20.08  ? 275 GLY R O   1 
ATOM   7677 N N   . VAL F 6 285 ? 113.505 131.109 149.480 1.00 19.80  ? 276 VAL R N   1 
ATOM   7678 C CA  . VAL F 6 285 ? 112.856 130.097 150.316 1.00 19.80  ? 276 VAL R CA  1 
ATOM   7679 C C   . VAL F 6 285 ? 113.582 129.884 151.636 1.00 19.80  ? 276 VAL R C   1 
ATOM   7680 O O   . VAL F 6 285 ? 112.910 129.781 152.673 1.00 19.80  ? 276 VAL R O   1 
ATOM   7681 C CB  . VAL F 6 285 ? 112.672 128.797 149.522 1.00 19.80  ? 276 VAL R CB  1 
ATOM   7682 C CG1 . VAL F 6 285 ? 112.098 127.712 150.418 1.00 19.80  ? 276 VAL R CG1 1 
ATOM   7683 C CG2 . VAL F 6 285 ? 111.758 129.035 148.334 1.00 19.80  ? 276 VAL R CG2 1 
ATOM   7684 N N   . PRO F 6 286 ? 114.916 129.797 151.694 1.00 22.08  ? 277 PRO R N   1 
ATOM   7685 C CA  . PRO F 6 286 ? 115.553 129.465 152.980 1.00 22.08  ? 277 PRO R CA  1 
ATOM   7686 C C   . PRO F 6 286 ? 115.189 130.409 154.112 1.00 22.08  ? 277 PRO R C   1 
ATOM   7687 O O   . PRO F 6 286 ? 115.176 129.985 155.274 1.00 22.08  ? 277 PRO R O   1 
ATOM   7688 C CB  . PRO F 6 286 ? 117.055 129.523 152.662 1.00 22.08  ? 277 PRO R CB  1 
ATOM   7689 C CG  . PRO F 6 286 ? 117.170 130.118 151.307 1.00 22.08  ? 277 PRO R CG  1 
ATOM   7690 C CD  . PRO F 6 286 ? 115.900 129.819 150.601 1.00 22.08  ? 277 PRO R CD  1 
ATOM   7691 N N   . LEU F 6 287 ? 114.891 131.675 153.815 1.00 21.97  ? 278 LEU R N   1 
ATOM   7692 C CA  . LEU F 6 287 ? 114.494 132.600 154.870 1.00 21.97  ? 278 LEU R CA  1 
ATOM   7693 C C   . LEU F 6 287 ? 113.307 132.058 155.654 1.00 21.97  ? 278 LEU R C   1 
ATOM   7694 O O   . LEU F 6 287 ? 113.243 132.207 156.880 1.00 21.97  ? 278 LEU R O   1 
ATOM   7695 C CB  . LEU F 6 287 ? 114.157 133.965 154.274 1.00 21.97  ? 278 LEU R CB  1 
ATOM   7696 C CG  . LEU F 6 287 ? 115.332 134.738 153.675 1.00 21.97  ? 278 LEU R CG  1 
ATOM   7697 C CD1 . LEU F 6 287 ? 114.832 135.886 152.818 1.00 21.97  ? 278 LEU R CD1 1 
ATOM   7698 C CD2 . LEU F 6 287 ? 116.249 135.249 154.769 1.00 21.97  ? 278 LEU R CD2 1 
ATOM   7699 N N   . LEU F 6 288 ? 112.374 131.397 154.966 1.00 22.58  ? 279 LEU R N   1 
ATOM   7700 C CA  . LEU F 6 288 ? 111.138 130.967 155.610 1.00 22.58  ? 279 LEU R CA  1 
ATOM   7701 C C   . LEU F 6 288 ? 111.415 130.043 156.788 1.00 22.58  ? 279 LEU R C   1 
ATOM   7702 O O   . LEU F 6 288 ? 110.821 130.196 157.860 1.00 22.58  ? 279 LEU R O   1 
ATOM   7703 C CB  . LEU F 6 288 ? 110.232 130.273 154.593 1.00 22.58  ? 279 LEU R CB  1 
ATOM   7704 C CG  . LEU F 6 288 ? 109.106 131.115 153.993 1.00 22.58  ? 279 LEU R CG  1 
ATOM   7705 C CD1 . LEU F 6 288 ? 108.414 130.352 152.877 1.00 22.58  ? 279 LEU R CD1 1 
ATOM   7706 C CD2 . LEU F 6 288 ? 108.102 131.513 155.063 1.00 22.58  ? 279 LEU R CD2 1 
ATOM   7707 N N   . PHE F 6 289 ? 112.305 129.067 156.611 1.00 25.87  ? 280 PHE R N   1 
ATOM   7708 C CA  . PHE F 6 289 ? 112.618 128.125 157.677 1.00 25.87  ? 280 PHE R CA  1 
ATOM   7709 C C   . PHE F 6 289 ? 113.888 128.486 158.435 1.00 25.87  ? 280 PHE R C   1 
ATOM   7710 O O   . PHE F 6 289 ? 114.279 127.744 159.341 1.00 25.87  ? 280 PHE R O   1 
ATOM   7711 C CB  . PHE F 6 289 ? 112.715 126.693 157.123 1.00 25.87  ? 280 PHE R CB  1 
ATOM   7712 C CG  . PHE F 6 289 ? 113.905 126.443 156.230 1.00 25.87  ? 280 PHE R CG  1 
ATOM   7713 C CD1 . PHE F 6 289 ? 115.175 126.287 156.758 1.00 25.87  ? 280 PHE R CD1 1 
ATOM   7714 C CD2 . PHE F 6 289 ? 113.741 126.321 154.863 1.00 25.87  ? 280 PHE R CD2 1 
ATOM   7715 C CE1 . PHE F 6 289 ? 116.257 126.044 155.937 1.00 25.87  ? 280 PHE R CE1 1 
ATOM   7716 C CE2 . PHE F 6 289 ? 114.821 126.074 154.041 1.00 25.87  ? 280 PHE R CE2 1 
ATOM   7717 C CZ  . PHE F 6 289 ? 116.079 125.936 154.579 1.00 25.87  ? 280 PHE R CZ  1 
ATOM   7718 N N   . VAL F 6 290 ? 114.537 129.595 158.097 1.00 27.94  ? 281 VAL R N   1 
ATOM   7719 C CA  . VAL F 6 290 ? 115.673 130.064 158.883 1.00 27.94  ? 281 VAL R CA  1 
ATOM   7720 C C   . VAL F 6 290 ? 115.237 131.073 159.940 1.00 27.94  ? 281 VAL R C   1 
ATOM   7721 O O   . VAL F 6 290 ? 115.685 131.008 161.086 1.00 27.94  ? 281 VAL R O   1 
ATOM   7722 C CB  . VAL F 6 290 ? 116.749 130.655 157.952 1.00 27.94  ? 281 VAL R CB  1 
ATOM   7723 C CG1 . VAL F 6 290 ? 117.772 131.446 158.752 1.00 27.94  ? 281 VAL R CG1 1 
ATOM   7724 C CG2 . VAL F 6 290 ? 117.429 129.550 157.164 1.00 27.94  ? 281 VAL R CG2 1 
ATOM   7725 N N   . VAL F 6 291 ? 114.362 132.016 159.578 1.00 31.59  ? 282 VAL R N   1 
ATOM   7726 C CA  . VAL F 6 291 ? 113.967 133.060 160.526 1.00 31.59  ? 282 VAL R CA  1 
ATOM   7727 C C   . VAL F 6 291 ? 113.280 132.482 161.757 1.00 31.59  ? 282 VAL R C   1 
ATOM   7728 O O   . VAL F 6 291 ? 113.644 132.869 162.880 1.00 31.59  ? 282 VAL R O   1 
ATOM   7729 C CB  . VAL F 6 291 ? 113.106 134.118 159.814 1.00 31.59  ? 282 VAL R CB  1 
ATOM   7730 C CG1 . VAL F 6 291 ? 112.403 135.002 160.828 1.00 31.59  ? 282 VAL R CG1 1 
ATOM   7731 C CG2 . VAL F 6 291 ? 113.967 134.952 158.883 1.00 31.59  ? 282 VAL R CG2 1 
ATOM   7732 N N   . PRO F 6 292 ? 112.296 131.588 161.637 1.00 34.62  ? 283 PRO R N   1 
ATOM   7733 C CA  . PRO F 6 292 ? 111.681 131.024 162.849 1.00 34.62  ? 283 PRO R CA  1 
ATOM   7734 C C   . PRO F 6 292 ? 112.677 130.336 163.760 1.00 34.62  ? 283 PRO R C   1 
ATOM   7735 O O   . PRO F 6 292 ? 112.514 130.378 164.985 1.00 34.62  ? 283 PRO R O   1 
ATOM   7736 C CB  . PRO F 6 292 ? 110.647 130.039 162.290 1.00 34.62  ? 283 PRO R CB  1 
ATOM   7737 C CG  . PRO F 6 292 ? 110.337 130.547 160.935 1.00 34.62  ? 283 PRO R CG  1 
ATOM   7738 C CD  . PRO F 6 292 ? 111.614 131.133 160.416 1.00 34.62  ? 283 PRO R CD  1 
ATOM   7739 N N   . TRP F 6 293 ? 113.706 129.695 163.202 1.00 39.62  ? 284 TRP R N   1 
ATOM   7740 C CA  . TRP F 6 293 ? 114.743 129.109 164.043 1.00 39.62  ? 284 TRP R CA  1 
ATOM   7741 C C   . TRP F 6 293 ? 115.442 130.178 164.869 1.00 39.62  ? 284 TRP R C   1 
ATOM   7742 O O   . TRP F 6 293 ? 115.669 129.998 166.072 1.00 39.62  ? 284 TRP R O   1 
ATOM   7743 C CB  . TRP F 6 293 ? 115.751 128.355 163.179 1.00 39.62  ? 284 TRP R CB  1 
ATOM   7744 C CG  . TRP F 6 293 ? 116.907 127.806 163.947 1.00 39.62  ? 284 TRP R CG  1 
ATOM   7745 C CD1 . TRP F 6 293 ? 116.922 126.676 164.708 1.00 39.62  ? 284 TRP R CD1 1 
ATOM   7746 C CD2 . TRP F 6 293 ? 118.224 128.362 164.028 1.00 39.62  ? 284 TRP R CD2 1 
ATOM   7747 N NE1 . TRP F 6 293 ? 118.165 126.493 165.259 1.00 39.62  ? 284 TRP R NE1 1 
ATOM   7748 C CE2 . TRP F 6 293 ? 118.983 127.515 164.856 1.00 39.62  ? 284 TRP R CE2 1 
ATOM   7749 C CE3 . TRP F 6 293 ? 118.833 129.493 163.481 1.00 39.62  ? 284 TRP R CE3 1 
ATOM   7750 C CZ2 . TRP F 6 293 ? 120.319 127.764 165.150 1.00 39.62  ? 284 TRP R CZ2 1 
ATOM   7751 C CZ3 . TRP F 6 293 ? 120.158 129.738 163.774 1.00 39.62  ? 284 TRP R CZ3 1 
ATOM   7752 C CH2 . TRP F 6 293 ? 120.886 128.879 164.601 1.00 39.62  ? 284 TRP R CH2 1 
ATOM   7753 N N   . GLY F 6 294 ? 115.785 131.305 164.242 1.00 42.87  ? 285 GLY R N   1 
ATOM   7754 C CA  . GLY F 6 294 ? 116.393 132.394 164.985 1.00 42.87  ? 285 GLY R CA  1 
ATOM   7755 C C   . GLY F 6 294 ? 115.479 132.933 166.066 1.00 42.87  ? 285 GLY R C   1 
ATOM   7756 O O   . GLY F 6 294 ? 115.921 133.222 167.180 1.00 42.87  ? 285 GLY R O   1 
ATOM   7757 N N   . ILE F 6 295 ? 114.190 133.073 165.755 1.00 44.48  ? 286 ILE R N   1 
ATOM   7758 C CA  . ILE F 6 295 ? 113.237 133.561 166.749 1.00 44.48  ? 286 ILE R CA  1 
ATOM   7759 C C   . ILE F 6 295 ? 113.186 132.612 167.939 1.00 44.48  ? 286 ILE R C   1 
ATOM   7760 O O   . ILE F 6 295 ? 113.224 133.036 169.100 1.00 44.48  ? 286 ILE R O   1 
ATOM   7761 C CB  . ILE F 6 295 ? 111.847 133.746 166.113 1.00 44.48  ? 286 ILE R CB  1 
ATOM   7762 C CG1 . ILE F 6 295 ? 111.748 135.116 165.441 1.00 44.48  ? 286 ILE R CG1 1 
ATOM   7763 C CG2 . ILE F 6 295 ? 110.749 133.591 167.158 1.00 44.48  ? 286 ILE R CG2 1 
ATOM   7764 C CD1 . ILE F 6 295 ? 110.569 135.251 164.501 1.00 44.48  ? 286 ILE R CD1 1 
ATOM   7765 N N   . VAL F 6 296 ? 113.091 131.309 167.665 1.00 50.08  ? 287 VAL R N   1 
ATOM   7766 C CA  . VAL F 6 296 ? 112.994 130.334 168.746 1.00 50.08  ? 287 VAL R CA  1 
ATOM   7767 C C   . VAL F 6 296 ? 114.256 130.358 169.596 1.00 50.08  ? 287 VAL R C   1 
ATOM   7768 O O   . VAL F 6 296 ? 114.191 130.316 170.831 1.00 50.08  ? 287 VAL R O   1 
ATOM   7769 C CB  . VAL F 6 296 ? 112.724 128.930 168.178 1.00 50.08  ? 287 VAL R CB  1 
ATOM   7770 C CG1 . VAL F 6 296 ? 112.809 127.887 169.283 1.00 50.08  ? 287 VAL R CG1 1 
ATOM   7771 C CG2 . VAL F 6 296 ? 111.365 128.891 167.494 1.00 50.08  ? 287 VAL R CG2 1 
ATOM   7772 N N   . LYS F 6 297 ? 115.422 130.425 168.955 1.00 54.88  ? 288 LYS R N   1 
ATOM   7773 C CA  . LYS F 6 297 ? 116.668 130.484 169.712 1.00 54.88  ? 288 LYS R CA  1 
ATOM   7774 C C   . LYS F 6 297 ? 116.726 131.736 170.576 1.00 54.88  ? 288 LYS R C   1 
ATOM   7775 O O   . LYS F 6 297 ? 117.144 131.678 171.738 1.00 54.88  ? 288 LYS R O   1 
ATOM   7776 C CB  . LYS F 6 297 ? 117.863 130.434 168.760 1.00 54.88  ? 288 LYS R CB  1 
ATOM   7777 C CG  . LYS F 6 297 ? 118.077 129.077 168.108 1.00 54.88  ? 288 LYS R CG  1 
ATOM   7778 C CD  . LYS F 6 297 ? 118.634 128.052 169.084 1.00 54.88  ? 288 LYS R CD  1 
ATOM   7779 C CE  . LYS F 6 297 ? 120.026 128.425 169.549 1.00 54.88  ? 288 LYS R CE  1 
ATOM   7780 N NZ  . LYS F 6 297 ? 120.841 127.239 169.922 1.00 54.88  ? 288 LYS R NZ  1 
ATOM   7781 N N   . TYR F 6 298 ? 116.305 132.878 170.030 1.00 56.46  ? 289 TYR R N   1 
ATOM   7782 C CA  . TYR F 6 298 ? 116.370 134.129 170.774 1.00 56.46  ? 289 TYR R CA  1 
ATOM   7783 C C   . TYR F 6 298 ? 115.360 134.186 171.910 1.00 56.46  ? 289 TYR R C   1 
ATOM   7784 O O   . TYR F 6 298 ? 115.588 134.909 172.885 1.00 56.46  ? 289 TYR R O   1 
ATOM   7785 C CB  . TYR F 6 298 ? 116.143 135.310 169.830 1.00 56.46  ? 289 TYR R CB  1 
ATOM   7786 C CG  . TYR F 6 298 ? 116.475 136.651 170.439 1.00 56.46  ? 289 TYR R CG  1 
ATOM   7787 C CD1 . TYR F 6 298 ? 117.793 137.039 170.636 1.00 56.46  ? 289 TYR R CD1 1 
ATOM   7788 C CD2 . TYR F 6 298 ? 115.470 137.530 170.817 1.00 56.46  ? 289 TYR R CD2 1 
ATOM   7789 C CE1 . TYR F 6 298 ? 118.101 138.264 171.191 1.00 56.46  ? 289 TYR R CE1 1 
ATOM   7790 C CE2 . TYR F 6 298 ? 115.769 138.758 171.373 1.00 56.46  ? 289 TYR R CE2 1 
ATOM   7791 C CZ  . TYR F 6 298 ? 117.086 139.120 171.558 1.00 56.46  ? 289 TYR R CZ  1 
ATOM   7792 O OH  . TYR F 6 298 ? 117.390 140.341 172.112 1.00 56.46  ? 289 TYR R OH  1 
ATOM   7793 N N   . LEU F 6 299 ? 114.253 133.453 171.807 1.00 52.18  ? 290 LEU R N   1 
ATOM   7794 C CA  . LEU F 6 299 ? 113.216 133.520 172.827 1.00 52.18  ? 290 LEU R CA  1 
ATOM   7795 C C   . LEU F 6 299 ? 113.286 132.400 173.854 1.00 52.18  ? 290 LEU R C   1 
ATOM   7796 O O   . LEU F 6 299 ? 112.712 132.550 174.939 1.00 52.18  ? 290 LEU R O   1 
ATOM   7797 C CB  . LEU F 6 299 ? 111.828 133.499 172.175 1.00 52.18  ? 290 LEU R CB  1 
ATOM   7798 C CG  . LEU F 6 299 ? 111.476 134.657 171.239 1.00 52.18  ? 290 LEU R CG  1 
ATOM   7799 C CD1 . LEU F 6 299 ? 109.984 134.664 170.952 1.00 52.18  ? 290 LEU R CD1 1 
ATOM   7800 C CD2 . LEU F 6 299 ? 111.917 135.993 171.814 1.00 52.18  ? 290 LEU R CD2 1 
ATOM   7801 N N   . TYR F 6 300 ? 113.954 131.292 173.555 1.00 55.95  ? 291 TYR R N   1 
ATOM   7802 C CA  . TYR F 6 300 ? 113.937 130.159 174.479 1.00 55.95  ? 291 TYR R CA  1 
ATOM   7803 C C   . TYR F 6 300 ? 115.319 129.632 174.834 1.00 55.95  ? 291 TYR R C   1 
ATOM   7804 O O   . TYR F 6 300 ? 115.530 129.219 175.977 1.00 55.95  ? 291 TYR R O   1 
ATOM   7805 C CB  . TYR F 6 300 ? 113.096 129.021 173.882 1.00 55.95  ? 291 TYR R CB  1 
ATOM   7806 C CG  . TYR F 6 300 ? 111.620 129.336 173.785 1.00 55.95  ? 291 TYR R CG  1 
ATOM   7807 C CD1 . TYR F 6 300 ? 111.135 130.184 172.800 1.00 55.95  ? 291 TYR R CD1 1 
ATOM   7808 C CD2 . TYR F 6 300 ? 110.713 128.785 174.678 1.00 55.95  ? 291 TYR R CD2 1 
ATOM   7809 C CE1 . TYR F 6 300 ? 109.788 130.473 172.707 1.00 55.95  ? 291 TYR R CE1 1 
ATOM   7810 C CE2 . TYR F 6 300 ? 109.364 129.068 174.593 1.00 55.95  ? 291 TYR R CE2 1 
ATOM   7811 C CZ  . TYR F 6 300 ? 108.908 129.912 173.605 1.00 55.95  ? 291 TYR R CZ  1 
ATOM   7812 O OH  . TYR F 6 300 ? 107.565 130.199 173.516 1.00 55.95  ? 291 TYR R OH  1 
ATOM   7813 N N   . GLU F 6 301 ? 116.261 129.631 173.897 1.00 62.77  ? 292 GLU R N   1 
ATOM   7814 C CA  . GLU F 6 301 ? 117.544 128.955 174.071 1.00 62.77  ? 292 GLU R CA  1 
ATOM   7815 C C   . GLU F 6 301 ? 118.695 129.862 173.658 1.00 62.77  ? 292 GLU R C   1 
ATOM   7816 O O   . GLU F 6 301 ? 119.590 129.469 172.907 1.00 62.77  ? 292 GLU R O   1 
ATOM   7817 C CB  . GLU F 6 301 ? 117.569 127.656 173.271 1.00 62.77  ? 292 GLU R CB  1 
ATOM   7818 C CG  . GLU F 6 301 ? 118.652 126.680 173.698 1.00 62.77  ? 292 GLU R CG  1 
ATOM   7819 C CD  . GLU F 6 301 ? 118.705 125.449 172.813 1.00 62.77  ? 292 GLU R CD  1 
ATOM   7820 O OE1 . GLU F 6 301 ? 117.708 125.177 172.113 1.00 62.77  ? 292 GLU R OE1 1 
ATOM   7821 O OE2 . GLU F 6 301 ? 119.743 124.756 172.818 1.00 62.77  ? 292 GLU R OE2 1 
ATOM   7822 N N   . ASP F 6 302 ? 118.691 131.098 174.151 1.00 62.98  ? 293 ASP R N   1 
ATOM   7823 C CA  . ASP F 6 302 ? 119.748 132.057 173.836 1.00 62.98  ? 293 ASP R CA  1 
ATOM   7824 C C   . ASP F 6 302 ? 120.850 131.925 174.878 1.00 62.98  ? 293 ASP R C   1 
ATOM   7825 O O   . ASP F 6 302 ? 120.711 132.389 176.012 1.00 62.98  ? 293 ASP R O   1 
ATOM   7826 C CB  . ASP F 6 302 ? 119.199 133.477 173.791 1.00 62.98  ? 293 ASP R CB  1 
ATOM   7827 C CG  . ASP F 6 302 ? 120.250 134.490 173.387 1.00 62.98  ? 293 ASP R CG  1 
ATOM   7828 O OD1 . ASP F 6 302 ? 121.080 134.168 172.511 1.00 62.98  ? 293 ASP R OD1 1 
ATOM   7829 O OD2 . ASP F 6 302 ? 120.252 135.607 173.946 1.00 62.98  ? 293 ASP R OD2 1 
ATOM   7830 N N   . GLU F 6 303 ? 121.956 131.292 174.488 1.00 69.48  ? 294 GLU R N   1 
ATOM   7831 C CA  . GLU F 6 303 ? 123.107 131.150 175.370 1.00 69.48  ? 294 GLU R CA  1 
ATOM   7832 C C   . GLU F 6 303 ? 124.308 130.622 174.597 1.00 69.48  ? 294 GLU R C   1 
ATOM   7833 O O   . GLU F 6 303 ? 124.172 129.714 173.772 1.00 69.48  ? 294 GLU R O   1 
ATOM   7834 C CB  . GLU F 6 303 ? 122.779 130.218 176.538 1.00 69.48  ? 294 GLU R CB  1 
ATOM   7835 C CG  . GLU F 6 303 ? 122.647 128.756 176.146 1.00 69.48  ? 294 GLU R CG  1 
ATOM   7836 C CD  . GLU F 6 303 ? 121.965 127.927 177.216 1.00 69.48  ? 294 GLU R CD  1 
ATOM   7837 O OE1 . GLU F 6 303 ? 122.301 128.097 178.407 1.00 69.48  ? 294 GLU R OE1 1 
ATOM   7838 O OE2 . GLU F 6 303 ? 121.094 127.103 176.866 1.00 69.48  ? 294 GLU R OE2 1 
ATOM   7839 N N   . GLY F 6 304 ? 125.484 131.185 174.854 1.00 66.38  ? 295 GLY R N   1 
ATOM   7840 C CA  . GLY F 6 304 ? 126.701 130.693 174.246 1.00 66.38  ? 295 GLY R CA  1 
ATOM   7841 C C   . GLY F 6 304 ? 126.722 130.773 172.734 1.00 66.38  ? 295 GLY R C   1 
ATOM   7842 O O   . GLY F 6 304 ? 127.043 129.789 172.063 1.00 66.38  ? 295 GLY R O   1 
ATOM   7843 N N   . CYS F 6 305 ? 126.375 131.934 172.184 1.00 66.68  ? 296 CYS R N   1 
ATOM   7844 C CA  . CYS F 6 305 ? 126.451 132.200 170.751 1.00 66.68  ? 296 CYS R CA  1 
ATOM   7845 C C   . CYS F 6 305 ? 125.524 131.312 169.933 1.00 66.68  ? 296 CYS R C   1 
ATOM   7846 O O   . CYS F 6 305 ? 125.691 131.212 168.713 1.00 66.68  ? 296 CYS R O   1 
ATOM   7847 C CB  . CYS F 6 305 ? 127.885 132.039 170.230 1.00 66.68  ? 296 CYS R CB  1 
ATOM   7848 S SG  . CYS F 6 305 ? 128.951 133.464 170.477 1.00 66.68  ? 296 CYS R SG  1 
ATOM   7849 N N   . TRP F 6 306 ? 124.553 130.657 170.565 1.00 59.76  ? 297 TRP R N   1 
ATOM   7850 C CA  . TRP F 6 306 ? 123.695 129.679 169.907 1.00 59.76  ? 297 TRP R CA  1 
ATOM   7851 C C   . TRP F 6 306 ? 124.486 128.504 169.348 1.00 59.76  ? 297 TRP R C   1 
ATOM   7852 O O   . TRP F 6 306 ? 123.941 127.707 168.574 1.00 59.76  ? 297 TRP R O   1 
ATOM   7853 C CB  . TRP F 6 306 ? 122.876 130.319 168.778 1.00 59.76  ? 297 TRP R CB  1 
ATOM   7854 C CG  . TRP F 6 306 ? 121.849 131.314 169.232 1.00 59.76  ? 297 TRP R CG  1 
ATOM   7855 C CD1 . TRP F 6 306 ? 121.263 131.390 170.460 1.00 59.76  ? 297 TRP R CD1 1 
ATOM   7856 C CD2 . TRP F 6 306 ? 121.278 132.369 168.450 1.00 59.76  ? 297 TRP R CD2 1 
ATOM   7857 N NE1 . TRP F 6 306 ? 120.366 132.431 170.493 1.00 59.76  ? 297 TRP R NE1 1 
ATOM   7858 C CE2 . TRP F 6 306 ? 120.357 133.046 169.270 1.00 59.76  ? 297 TRP R CE2 1 
ATOM   7859 C CE3 . TRP F 6 306 ? 121.459 132.807 167.135 1.00 59.76  ? 297 TRP R CE3 1 
ATOM   7860 C CZ2 . TRP F 6 306 ? 119.620 134.137 168.821 1.00 59.76  ? 297 TRP R CZ2 1 
ATOM   7861 C CZ3 . TRP F 6 306 ? 120.725 133.888 166.691 1.00 59.76  ? 297 TRP R CZ3 1 
ATOM   7862 C CH2 . TRP F 6 306 ? 119.819 134.543 167.531 1.00 59.76  ? 297 TRP R CH2 1 
ATOM   7863 N N   . THR F 6 307 ? 125.762 128.375 169.719 1.00 60.23  ? 298 THR R N   1 
ATOM   7864 C CA  . THR F 6 307 ? 126.631 127.392 169.080 1.00 60.23  ? 298 THR R CA  1 
ATOM   7865 C C   . THR F 6 307 ? 126.142 125.972 169.326 1.00 60.23  ? 298 THR R C   1 
ATOM   7866 O O   . THR F 6 307 ? 126.089 125.153 168.403 1.00 60.23  ? 298 THR R O   1 
ATOM   7867 C CB  . THR F 6 307 ? 128.062 127.554 169.589 1.00 60.23  ? 298 THR R CB  1 
ATOM   7868 O OG1 . THR F 6 307 ? 128.413 128.944 169.608 1.00 60.23  ? 298 THR R OG1 1 
ATOM   7869 C CG2 . THR F 6 307 ? 129.033 126.800 168.697 1.00 60.23  ? 298 THR R CG2 1 
ATOM   7870 N N   . ARG F 6 308 ? 125.775 125.662 170.565 1.00 67.60  ? 299 ARG R N   1 
ATOM   7871 C CA  . ARG F 6 308 ? 125.377 124.314 170.942 1.00 67.60  ? 299 ARG R CA  1 
ATOM   7872 C C   . ARG F 6 308 ? 123.859 124.203 170.910 1.00 67.60  ? 299 ARG R C   1 
ATOM   7873 O O   . ARG F 6 308 ? 123.156 125.061 171.453 1.00 67.60  ? 299 ARG R O   1 
ATOM   7874 C CB  . ARG F 6 308 ? 125.910 123.956 172.330 1.00 67.60  ? 299 ARG R CB  1 
ATOM   7875 C CG  . ARG F 6 308 ? 125.270 124.723 173.473 1.00 67.60  ? 299 ARG R CG  1 
ATOM   7876 C CD  . ARG F 6 308 ? 125.967 124.420 174.788 1.00 67.60  ? 299 ARG R CD  1 
ATOM   7877 N NE  . ARG F 6 308 ? 127.226 125.143 174.916 1.00 67.60  ? 299 ARG R NE  1 
ATOM   7878 C CZ  . ARG F 6 308 ? 127.320 126.443 175.160 1.00 67.60  ? 299 ARG R CZ  1 
ATOM   7879 N NH1 . ARG F 6 308 ? 126.245 127.196 175.325 1.00 67.60  ? 299 ARG R NH1 1 
ATOM   7880 N NH2 . ARG F 6 308 ? 128.524 127.002 175.241 1.00 67.60  ? 299 ARG R NH2 1 
ATOM   7881 N N   . ASN F 6 309 ? 123.365 123.149 170.272 1.00 66.35  ? 300 ASN R N   1 
ATOM   7882 C CA  . ASN F 6 309 ? 121.936 122.888 170.160 1.00 66.35  ? 300 ASN R CA  1 
ATOM   7883 C C   . ASN F 6 309 ? 121.543 121.858 171.210 1.00 66.35  ? 300 ASN R C   1 
ATOM   7884 O O   . ASN F 6 309 ? 122.071 120.741 171.219 1.00 66.35  ? 300 ASN R O   1 
ATOM   7885 C CB  . ASN F 6 309 ? 121.581 122.396 168.756 1.00 66.35  ? 300 ASN R CB  1 
ATOM   7886 C CG  . ASN F 6 309 ? 122.530 121.324 168.254 1.00 66.35  ? 300 ASN R CG  1 
ATOM   7887 O OD1 . ASN F 6 309 ? 123.427 120.887 168.975 1.00 66.35  ? 300 ASN R OD1 1 
ATOM   7888 N ND2 . ASN F 6 309 ? 122.339 120.900 167.011 1.00 66.35  ? 300 ASN R ND2 1 
ATOM   7889 N N   . SER F 6 310 ? 120.617 122.235 172.091 1.00 75.80  ? 301 SER R N   1 
ATOM   7890 C CA  . SER F 6 310 ? 120.195 121.377 173.194 1.00 75.80  ? 301 SER R CA  1 
ATOM   7891 C C   . SER F 6 310 ? 118.925 120.603 172.859 1.00 75.80  ? 301 SER R C   1 
ATOM   7892 O O   . SER F 6 310 ? 118.898 119.374 172.965 1.00 75.80  ? 301 SER R O   1 
ATOM   7893 C CB  . SER F 6 310 ? 119.989 122.220 174.459 1.00 75.80  ? 301 SER R CB  1 
ATOM   7894 O OG  . SER F 6 310 ? 121.178 122.907 174.811 1.00 75.80  ? 301 SER R OG  1 
ATOM   7895 N N   . ASN F 6 311 ? 117.868 121.304 172.460 1.00 75.66  ? 302 ASN R N   1 
ATOM   7896 C CA  . ASN F 6 311 ? 116.592 120.673 172.152 1.00 75.66  ? 302 ASN R CA  1 
ATOM   7897 C C   . ASN F 6 311 ? 116.543 120.333 170.665 1.00 75.66  ? 302 ASN R C   1 
ATOM   7898 O O   . ASN F 6 311 ? 116.553 121.232 169.817 1.00 75.66  ? 302 ASN R O   1 
ATOM   7899 C CB  . ASN F 6 311 ? 115.434 121.595 172.534 1.00 75.66  ? 302 ASN R CB  1 
ATOM   7900 C CG  . ASN F 6 311 ? 114.154 120.836 172.817 1.00 75.66  ? 302 ASN R CG  1 
ATOM   7901 O OD1 . ASN F 6 311 ? 113.978 119.703 172.369 1.00 75.66  ? 302 ASN R OD1 1 
ATOM   7902 N ND2 . ASN F 6 311 ? 113.250 121.458 173.565 1.00 75.66  ? 302 ASN R ND2 1 
ATOM   7903 N N   . MET F 6 312 ? 116.487 119.035 170.354 1.00 72.70  ? 303 MET R N   1 
ATOM   7904 C CA  . MET F 6 312 ? 116.438 118.611 168.958 1.00 72.70  ? 303 MET R CA  1 
ATOM   7905 C C   . MET F 6 312 ? 115.210 119.159 168.247 1.00 72.70  ? 303 MET R C   1 
ATOM   7906 O O   . MET F 6 312 ? 115.223 119.319 167.020 1.00 72.70  ? 303 MET R O   1 
ATOM   7907 C CB  . MET F 6 312 ? 116.455 117.084 168.872 1.00 72.70  ? 303 MET R CB  1 
ATOM   7908 C CG  . MET F 6 312 ? 117.767 116.408 169.278 1.00 72.70  ? 303 MET R CG  1 
ATOM   7909 S SD  . MET F 6 312 ? 119.277 117.307 168.860 1.00 72.70  ? 303 MET R SD  1 
ATOM   7910 C CE  . MET F 6 312 ? 119.491 118.357 170.293 1.00 72.70  ? 303 MET R CE  1 
ATOM   7911 N N   . ASN F 6 313 ? 114.137 119.441 168.988 1.00 75.30  ? 304 ASN R N   1 
ATOM   7912 C CA  . ASN F 6 313 ? 112.963 120.044 168.369 1.00 75.30  ? 304 ASN R CA  1 
ATOM   7913 C C   . ASN F 6 313 ? 113.314 121.384 167.736 1.00 75.30  ? 304 ASN R C   1 
ATOM   7914 O O   . ASN F 6 313 ? 112.838 121.708 166.642 1.00 75.30  ? 304 ASN R O   1 
ATOM   7915 C CB  . ASN F 6 313 ? 111.849 120.214 169.401 1.00 75.30  ? 304 ASN R CB  1 
ATOM   7916 C CG  . ASN F 6 313 ? 111.215 118.896 169.797 1.00 75.30  ? 304 ASN R CG  1 
ATOM   7917 O OD1 . ASN F 6 313 ? 110.995 118.024 168.956 1.00 75.30  ? 304 ASN R OD1 1 
ATOM   7918 N ND2 . ASN F 6 313 ? 110.909 118.746 171.080 1.00 75.30  ? 304 ASN R ND2 1 
ATOM   7919 N N   . TYR F 6 314 ? 114.150 122.171 168.406 1.00 64.06  ? 305 TYR R N   1 
ATOM   7920 C CA  . TYR F 6 314 ? 114.590 123.456 167.881 1.00 64.06  ? 305 TYR R CA  1 
ATOM   7921 C C   . TYR F 6 314 ? 115.756 123.326 166.911 1.00 64.06  ? 305 TYR R C   1 
ATOM   7922 O O   . TYR F 6 314 ? 116.259 124.349 166.434 1.00 64.06  ? 305 TYR R O   1 
ATOM   7923 C CB  . TYR F 6 314 ? 114.979 124.385 169.034 1.00 64.06  ? 305 TYR R CB  1 
ATOM   7924 C CG  . TYR F 6 314 ? 113.896 124.548 170.078 1.00 64.06  ? 305 TYR R CG  1 
ATOM   7925 C CD1 . TYR F 6 314 ? 112.554 124.452 169.737 1.00 64.06  ? 305 TYR R CD1 1 
ATOM   7926 C CD2 . TYR F 6 314 ? 114.216 124.798 171.405 1.00 64.06  ? 305 TYR R CD2 1 
ATOM   7927 C CE1 . TYR F 6 314 ? 111.563 124.600 170.685 1.00 64.06  ? 305 TYR R CE1 1 
ATOM   7928 C CE2 . TYR F 6 314 ? 113.230 124.947 172.361 1.00 64.06  ? 305 TYR R CE2 1 
ATOM   7929 C CZ  . TYR F 6 314 ? 111.906 124.846 171.996 1.00 64.06  ? 305 TYR R CZ  1 
ATOM   7930 O OH  . TYR F 6 314 ? 110.919 124.993 172.945 1.00 64.06  ? 305 TYR R OH  1 
ATOM   7931 N N   . TRP F 6 315 ? 116.180 122.098 166.603 1.00 53.10  ? 306 TRP R N   1 
ATOM   7932 C CA  . TRP F 6 315 ? 117.319 121.845 165.682 1.00 53.10  ? 306 TRP R CA  1 
ATOM   7933 C C   . TRP F 6 315 ? 116.809 121.279 164.360 1.00 53.10  ? 306 TRP R C   1 
ATOM   7934 O O   . TRP F 6 315 ? 117.365 121.665 163.319 1.00 53.10  ? 306 TRP R O   1 
ATOM   7935 C CB  . TRP F 6 315 ? 118.336 120.909 166.343 1.00 53.10  ? 306 TRP R CB  1 
ATOM   7936 C CG  . TRP F 6 315 ? 119.419 120.394 165.446 1.00 53.10  ? 306 TRP R CG  1 
ATOM   7937 C CD1 . TRP F 6 315 ? 119.946 119.137 165.461 1.00 53.10  ? 306 TRP R CD1 1 
ATOM   7938 C CD2 . TRP F 6 315 ? 120.132 121.113 164.421 1.00 53.10  ? 306 TRP R CD2 1 
ATOM   7939 N NE1 . TRP F 6 315 ? 120.929 119.018 164.516 1.00 53.10  ? 306 TRP R NE1 1 
ATOM   7940 C CE2 . TRP F 6 315 ? 121.065 120.213 163.863 1.00 53.10  ? 306 TRP R CE2 1 
ATOM   7941 C CE3 . TRP F 6 315 ? 120.077 122.417 163.919 1.00 53.10  ? 306 TRP R CE3 1 
ATOM   7942 C CZ2 . TRP F 6 315 ? 121.927 120.577 162.831 1.00 53.10  ? 306 TRP R CZ2 1 
ATOM   7943 C CZ3 . TRP F 6 315 ? 120.929 122.775 162.898 1.00 53.10  ? 306 TRP R CZ3 1 
ATOM   7944 C CH2 . TRP F 6 315 ? 121.841 121.867 162.363 1.00 53.10  ? 306 TRP R CH2 1 
ATOM   7945 N N   . LEU F 6 316 ? 115.780 120.427 164.375 1.00 50.64  ? 307 LEU R N   1 
ATOM   7946 C CA  . LEU F 6 316 ? 115.323 119.778 163.153 1.00 50.64  ? 307 LEU R CA  1 
ATOM   7947 C C   . LEU F 6 316 ? 114.753 120.766 162.143 1.00 50.64  ? 307 LEU R C   1 
ATOM   7948 O O   . LEU F 6 316 ? 114.600 120.413 160.966 1.00 50.64  ? 307 LEU R O   1 
ATOM   7949 C CB  . LEU F 6 316 ? 114.270 118.722 163.488 1.00 50.64  ? 307 LEU R CB  1 
ATOM   7950 C CG  . LEU F 6 316 ? 114.800 117.466 164.181 1.00 50.64  ? 307 LEU R CG  1 
ATOM   7951 C CD1 . LEU F 6 316 ? 113.657 116.680 164.799 1.00 50.64  ? 307 LEU R CD1 1 
ATOM   7952 C CD2 . LEU F 6 316 ? 115.582 116.602 163.208 1.00 50.64  ? 307 LEU R CD2 1 
ATOM   7953 N N   . ILE F 6 317 ? 114.435 121.988 162.573 1.00 40.95  ? 308 ILE R N   1 
ATOM   7954 C CA  . ILE F 6 317 ? 113.861 122.972 161.660 1.00 40.95  ? 308 ILE R CA  1 
ATOM   7955 C C   . ILE F 6 317 ? 114.832 123.273 160.528 1.00 40.95  ? 308 ILE R C   1 
ATOM   7956 O O   . ILE F 6 317 ? 114.438 123.360 159.359 1.00 40.95  ? 308 ILE R O   1 
ATOM   7957 C CB  . ILE F 6 317 ? 113.476 124.251 162.428 1.00 40.95  ? 308 ILE R CB  1 
ATOM   7958 C CG1 . ILE F 6 317 ? 112.263 123.989 163.323 1.00 40.95  ? 308 ILE R CG1 1 
ATOM   7959 C CG2 . ILE F 6 317 ? 113.177 125.380 161.457 1.00 40.95  ? 308 ILE R CG2 1 
ATOM   7960 C CD1 . ILE F 6 317 ? 112.071 125.029 164.404 1.00 40.95  ? 308 ILE R CD1 1 
ATOM   7961 N N   . ILE F 6 318 ? 116.112 123.436 160.863 1.00 36.79  ? 309 ILE R N   1 
ATOM   7962 C CA  . ILE F 6 318 ? 117.149 123.809 159.858 1.00 36.79  ? 309 ILE R CA  1 
ATOM   7963 C C   . ILE F 6 318 ? 117.792 122.539 159.297 1.00 36.79  ? 309 ILE R C   1 
ATOM   7964 O O   . ILE F 6 318 ? 118.864 122.653 158.691 1.00 36.79  ? 309 ILE R O   1 
ATOM   7965 C CB  . ILE F 6 318 ? 118.183 124.757 160.496 1.00 36.79  ? 309 ILE R CB  1 
ATOM   7966 C CG1 . ILE F 6 318 ? 117.513 125.934 161.207 1.00 36.79  ? 309 ILE R CG1 1 
ATOM   7967 C CG2 . ILE F 6 318 ? 119.188 125.239 159.463 1.00 36.79  ? 309 ILE R CG2 1 
ATOM   7968 C CD1 . ILE F 6 318 ? 116.823 126.886 160.266 1.00 36.79  ? 309 ILE R CD1 1 
ATOM   7969 N N   . ARG F 6 319 ? 117.160 121.378 159.469 1.00 46.32  ? 310 ARG R N   1 
ATOM   7970 C CA  . ARG F 6 319 ? 117.687 120.089 158.950 1.00 46.32  ? 310 ARG R CA  1 
ATOM   7971 C C   . ARG F 6 319 ? 116.685 119.435 157.995 1.00 46.32  ? 310 ARG R C   1 
ATOM   7972 O O   . ARG F 6 319 ? 117.148 118.861 156.996 1.00 46.32  ? 310 ARG R O   1 
ATOM   7973 C CB  . ARG F 6 319 ? 117.994 119.117 160.091 1.00 46.32  ? 310 ARG R CB  1 
ATOM   7974 C CG  . ARG F 6 319 ? 119.299 119.397 160.820 1.00 46.32  ? 310 ARG R CG  1 
ATOM   7975 C CD  . ARG F 6 319 ? 119.744 118.192 161.624 1.00 46.32  ? 310 ARG R CD  1 
ATOM   7976 N NE  . ARG F 6 319 ? 118.904 117.972 162.793 1.00 46.32  ? 310 ARG R NE  1 
ATOM   7977 C CZ  . ARG F 6 319 ? 119.024 116.949 163.633 1.00 46.32  ? 310 ARG R CZ  1 
ATOM   7978 N NH1 . ARG F 6 319 ? 119.954 116.028 163.441 1.00 46.32  ? 310 ARG R NH1 1 
ATOM   7979 N NH2 . ARG F 6 319 ? 118.209 116.852 164.668 1.00 46.32  ? 310 ARG R NH2 1 
ATOM   7980 N N   . LEU F 6 320 ? 115.379 119.500 158.263 1.00 38.79  ? 311 LEU R N   1 
ATOM   7981 C CA  . LEU F 6 320 ? 114.385 118.798 157.449 1.00 38.79  ? 311 LEU R CA  1 
ATOM   7982 C C   . LEU F 6 320 ? 114.381 119.261 155.997 1.00 38.79  ? 311 LEU R C   1 
ATOM   7983 O O   . LEU F 6 320 ? 114.478 118.408 155.093 1.00 38.79  ? 311 LEU R O   1 
ATOM   7984 C CB  . LEU F 6 320 ? 113.001 118.967 158.082 1.00 38.79  ? 311 LEU R CB  1 
ATOM   7985 C CG  . LEU F 6 320 ? 112.491 117.786 158.904 1.00 38.79  ? 311 LEU R CG  1 
ATOM   7986 C CD1 . LEU F 6 320 ? 113.513 117.386 159.953 1.00 38.79  ? 311 LEU R CD1 1 
ATOM   7987 C CD2 . LEU F 6 320 ? 111.160 118.127 159.554 1.00 38.79  ? 311 LEU R CD2 1 
ATOM   7988 N N   . PRO F 6 321 ? 114.278 120.556 155.697 1.00 29.56  ? 312 PRO R N   1 
ATOM   7989 C CA  . PRO F 6 321 ? 114.243 120.976 154.288 1.00 29.56  ? 312 PRO R CA  1 
ATOM   7990 C C   . PRO F 6 321 ? 115.476 120.566 153.504 1.00 29.56  ? 312 PRO R C   1 
ATOM   7991 O O   . PRO F 6 321 ? 115.375 120.280 152.303 1.00 29.56  ? 312 PRO R O   1 
ATOM   7992 C CB  . PRO F 6 321 ? 114.114 122.502 154.383 1.00 29.56  ? 312 PRO R CB  1 
ATOM   7993 C CG  . PRO F 6 321 ? 113.563 122.762 155.742 1.00 29.56  ? 312 PRO R CG  1 
ATOM   7994 C CD  . PRO F 6 321 ? 114.118 121.693 156.618 1.00 29.56  ? 312 PRO R CD  1 
ATOM   7995 N N   . ILE F 6 322 ? 116.626 120.540 154.179 1.00 29.16  ? 313 ILE R N   1 
ATOM   7996 C CA  . ILE F 6 322 ? 117.909 120.163 153.528 1.00 29.16  ? 313 ILE R CA  1 
ATOM   7997 C C   . ILE F 6 322 ? 117.776 118.716 153.061 1.00 29.16  ? 313 ILE R C   1 
ATOM   7998 O O   . ILE F 6 322 ? 118.124 118.466 151.910 1.00 29.16  ? 313 ILE R O   1 
ATOM   7999 C CB  . ILE F 6 322 ? 119.101 120.386 154.473 1.00 29.16  ? 313 ILE R CB  1 
ATOM   8000 C CG1 . ILE F 6 322 ? 119.406 121.879 154.620 1.00 29.16  ? 313 ILE R CG1 1 
ATOM   8001 C CG2 . ILE F 6 322 ? 120.319 119.606 154.006 1.00 29.16  ? 313 ILE R CG2 1 
ATOM   8002 C CD1 . ILE F 6 322 ? 120.554 122.192 155.546 1.00 29.16  ? 313 ILE R CD1 1 
ATOM   8003 N N   . LEU F 6 323 ? 117.265 117.808 153.891 1.00 33.98  ? 314 LEU R N   1 
ATOM   8004 C CA  . LEU F 6 323 ? 117.059 116.414 153.516 1.00 33.98  ? 314 LEU R CA  1 
ATOM   8005 C C   . LEU F 6 323 ? 116.054 116.304 152.378 1.00 33.98  ? 314 LEU R C   1 
ATOM   8006 O O   . LEU F 6 323 ? 116.229 115.499 151.454 1.00 33.98  ? 314 LEU R O   1 
ATOM   8007 C CB  . LEU F 6 323 ? 116.586 115.608 154.725 1.00 33.98  ? 314 LEU R CB  1 
ATOM   8008 C CG  . LEU F 6 323 ? 117.452 115.701 155.982 1.00 33.98  ? 314 LEU R CG  1 
ATOM   8009 C CD1 . LEU F 6 323 ? 116.732 115.083 157.169 1.00 33.98  ? 314 LEU R CD1 1 
ATOM   8010 C CD2 . LEU F 6 323 ? 118.796 115.033 155.759 1.00 33.98  ? 314 LEU R CD2 1 
ATOM   8011 N N   . PHE F 6 324 ? 114.988 117.105 152.436 1.00 25.86  ? 315 PHE R N   1 
ATOM   8012 C CA  . PHE F 6 324 ? 114.011 117.122 151.351 1.00 25.86  ? 315 PHE R CA  1 
ATOM   8013 C C   . PHE F 6 324 ? 114.681 117.442 150.015 1.00 25.86  ? 315 PHE R C   1 
ATOM   8014 O O   . PHE F 6 324 ? 114.478 116.740 149.011 1.00 25.86  ? 315 PHE R O   1 
ATOM   8015 C CB  . PHE F 6 324 ? 112.922 118.143 151.686 1.00 25.86  ? 315 PHE R CB  1 
ATOM   8016 C CG  . PHE F 6 324 ? 111.941 118.388 150.580 1.00 25.86  ? 315 PHE R CG  1 
ATOM   8017 C CD1 . PHE F 6 324 ? 112.182 119.357 149.623 1.00 25.86  ? 315 PHE R CD1 1 
ATOM   8018 C CD2 . PHE F 6 324 ? 110.759 117.674 150.517 1.00 25.86  ? 315 PHE R CD2 1 
ATOM   8019 C CE1 . PHE F 6 324 ? 111.274 119.593 148.612 1.00 25.86  ? 315 PHE R CE1 1 
ATOM   8020 C CE2 . PHE F 6 324 ? 109.846 117.905 149.508 1.00 25.86  ? 315 PHE R CE2 1 
ATOM   8021 C CZ  . PHE F 6 324 ? 110.104 118.867 148.556 1.00 25.86  ? 315 PHE R CZ  1 
ATOM   8022 N N   . ALA F 6 325 ? 115.500 118.495 149.993 1.00 24.17  ? 316 ALA R N   1 
ATOM   8023 C CA  . ALA F 6 325 ? 116.162 118.897 148.756 1.00 24.17  ? 316 ALA R CA  1 
ATOM   8024 C C   . ALA F 6 325 ? 117.111 117.816 148.252 1.00 24.17  ? 316 ALA R C   1 
ATOM   8025 O O   . ALA F 6 325 ? 117.182 117.552 147.044 1.00 24.17  ? 316 ALA R O   1 
ATOM   8026 C CB  . ALA F 6 325 ? 116.913 120.210 148.969 1.00 24.17  ? 316 ALA R CB  1 
ATOM   8027 N N   . ILE F 6 326 ? 117.861 117.186 149.160 1.00 27.76  ? 317 ILE R N   1 
ATOM   8028 C CA  . ILE F 6 326 ? 118.783 116.131 148.745 1.00 27.76  ? 317 ILE R CA  1 
ATOM   8029 C C   . ILE F 6 326 ? 118.022 114.963 148.133 1.00 27.76  ? 317 ILE R C   1 
ATOM   8030 O O   . ILE F 6 326 ? 118.439 114.396 147.113 1.00 27.76  ? 317 ILE R O   1 
ATOM   8031 C CB  . ILE F 6 326 ? 119.658 115.684 149.930 1.00 27.76  ? 317 ILE R CB  1 
ATOM   8032 C CG1 . ILE F 6 326 ? 120.466 116.870 150.464 1.00 27.76  ? 317 ILE R CG1 1 
ATOM   8033 C CG2 . ILE F 6 326 ? 120.575 114.545 149.506 1.00 27.76  ? 317 ILE R CG2 1 
ATOM   8034 C CD1 . ILE F 6 326 ? 121.400 116.526 151.606 1.00 27.76  ? 317 ILE R CD1 1 
ATOM   8035 N N   . GLY F 6 327 ? 116.903 114.572 148.745 1.00 23.00  ? 318 GLY R N   1 
ATOM   8036 C CA  . GLY F 6 327 ? 116.101 113.507 148.163 1.00 23.00  ? 318 GLY R CA  1 
ATOM   8037 C C   . GLY F 6 327 ? 115.609 113.851 146.769 1.00 23.00  ? 318 GLY R C   1 
ATOM   8038 O O   . GLY F 6 327 ? 115.654 113.019 145.854 1.00 23.00  ? 318 GLY R O   1 
ATOM   8039 N N   . VAL F 6 328 ? 115.140 115.087 146.585 1.00 20.48  ? 319 VAL R N   1 
ATOM   8040 C CA  . VAL F 6 328 ? 114.650 115.492 145.269 1.00 20.48  ? 319 VAL R CA  1 
ATOM   8041 C C   . VAL F 6 328 ? 115.774 115.425 144.238 1.00 20.48  ? 319 VAL R C   1 
ATOM   8042 O O   . VAL F 6 328 ? 115.586 114.928 143.119 1.00 20.48  ? 319 VAL R O   1 
ATOM   8043 C CB  . VAL F 6 328 ? 114.027 116.896 145.340 1.00 20.48  ? 319 VAL R CB  1 
ATOM   8044 C CG1 . VAL F 6 328 ? 113.668 117.384 143.951 1.00 20.48  ? 319 VAL R CG1 1 
ATOM   8045 C CG2 . VAL F 6 328 ? 112.791 116.873 146.224 1.00 20.48  ? 319 VAL R CG2 1 
ATOM   8046 N N   . ASN F 6 329 ? 116.958 115.928 144.596 1.00 21.91  ? 320 ASN R N   1 
ATOM   8047 C CA  . ASN F 6 329 ? 118.084 115.869 143.664 1.00 21.91  ? 320 ASN R CA  1 
ATOM   8048 C C   . ASN F 6 329 ? 118.457 114.434 143.327 1.00 21.91  ? 320 ASN R C   1 
ATOM   8049 O O   . ASN F 6 329 ? 118.825 114.136 142.186 1.00 21.91  ? 320 ASN R O   1 
ATOM   8050 C CB  . ASN F 6 329 ? 119.294 116.609 144.229 1.00 21.91  ? 320 ASN R CB  1 
ATOM   8051 C CG  . ASN F 6 329 ? 119.093 118.100 144.258 1.00 21.91  ? 320 ASN R CG  1 
ATOM   8052 O OD1 . ASN F 6 329 ? 118.562 118.675 143.310 1.00 21.91  ? 320 ASN R OD1 1 
ATOM   8053 N ND2 . ASN F 6 329 ? 119.512 118.742 145.342 1.00 21.91  ? 320 ASN R ND2 1 
ATOM   8054 N N   . PHE F 6 330 ? 118.386 113.528 144.303 1.00 23.94  ? 321 PHE R N   1 
ATOM   8055 C CA  . PHE F 6 330 ? 118.679 112.132 143.995 1.00 23.94  ? 321 PHE R CA  1 
ATOM   8056 C C   . PHE F 6 330 ? 117.670 111.569 143.001 1.00 23.94  ? 321 PHE R C   1 
ATOM   8057 O O   . PHE F 6 330 ? 118.040 110.838 142.071 1.00 23.94  ? 321 PHE R O   1 
ATOM   8058 C CB  . PHE F 6 330 ? 118.699 111.296 145.270 1.00 23.94  ? 321 PHE R CB  1 
ATOM   8059 C CG  . PHE F 6 330 ? 119.416 109.987 145.115 1.00 23.94  ? 321 PHE R CG  1 
ATOM   8060 C CD1 . PHE F 6 330 ? 120.750 109.955 144.750 1.00 23.94  ? 321 PHE R CD1 1 
ATOM   8061 C CD2 . PHE F 6 330 ? 118.755 108.791 145.321 1.00 23.94  ? 321 PHE R CD2 1 
ATOM   8062 C CE1 . PHE F 6 330 ? 121.413 108.755 144.601 1.00 23.94  ? 321 PHE R CE1 1 
ATOM   8063 C CE2 . PHE F 6 330 ? 119.415 107.588 145.173 1.00 23.94  ? 321 PHE R CE2 1 
ATOM   8064 C CZ  . PHE F 6 330 ? 120.747 107.572 144.812 1.00 23.94  ? 321 PHE R CZ  1 
ATOM   8065 N N   . LEU F 6 331 ? 116.387 111.897 143.176 1.00 21.04  ? 322 LEU R N   1 
ATOM   8066 C CA  . LEU F 6 331 ? 115.388 111.440 142.211 1.00 21.04  ? 322 LEU R CA  1 
ATOM   8067 C C   . LEU F 6 331 ? 115.696 111.966 140.814 1.00 21.04  ? 322 LEU R C   1 
ATOM   8068 O O   . LEU F 6 331 ? 115.610 111.224 139.822 1.00 21.04  ? 322 LEU R O   1 
ATOM   8069 C CB  . LEU F 6 331 ? 113.990 111.882 142.644 1.00 21.04  ? 322 LEU R CB  1 
ATOM   8070 C CG  . LEU F 6 331 ? 113.417 111.298 143.936 1.00 21.04  ? 322 LEU R CG  1 
ATOM   8071 C CD1 . LEU F 6 331 ? 111.903 111.423 143.935 1.00 21.04  ? 322 LEU R CD1 1 
ATOM   8072 C CD2 . LEU F 6 331 ? 113.829 109.851 144.133 1.00 21.04  ? 322 LEU R CD2 1 
ATOM   8073 N N   . ILE F 6 332 ? 116.052 113.248 140.714 1.00 19.78  ? 323 ILE R N   1 
ATOM   8074 C CA  . ILE F 6 332 ? 116.375 113.827 139.412 1.00 19.78  ? 323 ILE R CA  1 
ATOM   8075 C C   . ILE F 6 332 ? 117.568 113.110 138.795 1.00 19.78  ? 323 ILE R C   1 
ATOM   8076 O O   . ILE F 6 332 ? 117.590 112.828 137.590 1.00 19.78  ? 323 ILE R O   1 
ATOM   8077 C CB  . ILE F 6 332 ? 116.638 115.338 139.547 1.00 19.78  ? 323 ILE R CB  1 
ATOM   8078 C CG1 . ILE F 6 332 ? 115.405 116.063 140.093 1.00 19.78  ? 323 ILE R CG1 1 
ATOM   8079 C CG2 . ILE F 6 332 ? 117.046 115.924 138.208 1.00 19.78  ? 323 ILE R CG2 1 
ATOM   8080 C CD1 . ILE F 6 332 ? 114.104 115.681 139.428 1.00 19.78  ? 323 ILE R CD1 1 
ATOM   8081 N N   . PHE F 6 333 ? 118.588 112.828 139.604 1.00 22.77  ? 324 PHE R N   1 
ATOM   8082 C CA  . PHE F 6 333 ? 119.753 112.101 139.112 1.00 22.77  ? 324 PHE R CA  1 
ATOM   8083 C C   . PHE F 6 333 ? 119.345 110.752 138.543 1.00 22.77  ? 324 PHE R C   1 
ATOM   8084 O O   . PHE F 6 333 ? 119.786 110.361 137.455 1.00 22.77  ? 324 PHE R O   1 
ATOM   8085 C CB  . PHE F 6 333 ? 120.760 111.939 140.253 1.00 22.77  ? 324 PHE R CB  1 
ATOM   8086 C CG  . PHE F 6 333 ? 121.825 110.911 140.000 1.00 22.77  ? 324 PHE R CG  1 
ATOM   8087 C CD1 . PHE F 6 333 ? 121.597 109.574 140.272 1.00 22.77  ? 324 PHE R CD1 1 
ATOM   8088 C CD2 . PHE F 6 333 ? 123.067 111.286 139.520 1.00 22.77  ? 324 PHE R CD2 1 
ATOM   8089 C CE1 . PHE F 6 333 ? 122.579 108.632 140.050 1.00 22.77  ? 324 PHE R CE1 1 
ATOM   8090 C CE2 . PHE F 6 333 ? 124.051 110.347 139.298 1.00 22.77  ? 324 PHE R CE2 1 
ATOM   8091 C CZ  . PHE F 6 333 ? 123.808 109.020 139.564 1.00 22.77  ? 324 PHE R CZ  1 
ATOM   8092 N N   . VAL F 6 334 ? 118.486 110.032 139.264 1.00 22.53  ? 325 VAL R N   1 
ATOM   8093 C CA  . VAL F 6 334 ? 118.053 108.714 138.801 1.00 22.53  ? 325 VAL R CA  1 
ATOM   8094 C C   . VAL F 6 334 ? 117.353 108.827 137.451 1.00 22.53  ? 325 VAL R C   1 
ATOM   8095 O O   . VAL F 6 334 ? 117.641 108.069 136.517 1.00 22.53  ? 325 VAL R O   1 
ATOM   8096 C CB  . VAL F 6 334 ? 117.145 108.047 139.849 1.00 22.53  ? 325 VAL R CB  1 
ATOM   8097 C CG1 . VAL F 6 334 ? 116.608 106.731 139.320 1.00 22.53  ? 325 VAL R CG1 1 
ATOM   8098 C CG2 . VAL F 6 334 ? 117.909 107.810 141.138 1.00 22.53  ? 325 VAL R CG2 1 
ATOM   8099 N N   . ARG F 6 335 ? 116.418 109.770 137.331 1.00 23.51  ? 326 ARG R N   1 
ATOM   8100 C CA  . ARG F 6 335 ? 115.657 109.876 136.087 1.00 23.51  ? 326 ARG R CA  1 
ATOM   8101 C C   . ARG F 6 335 ? 116.551 110.281 134.919 1.00 23.51  ? 326 ARG R C   1 
ATOM   8102 O O   . ARG F 6 335 ? 116.410 109.752 133.807 1.00 23.51  ? 326 ARG R O   1 
ATOM   8103 C CB  . ARG F 6 335 ? 114.503 110.860 136.255 1.00 23.51  ? 326 ARG R CB  1 
ATOM   8104 C CG  . ARG F 6 335 ? 113.199 110.192 136.667 1.00 23.51  ? 326 ARG R CG  1 
ATOM   8105 C CD  . ARG F 6 335 ? 113.423 109.201 137.800 1.00 23.51  ? 326 ARG R CD  1 
ATOM   8106 N NE  . ARG F 6 335 ? 112.180 108.784 138.434 1.00 23.51  ? 326 ARG R NE  1 
ATOM   8107 C CZ  . ARG F 6 335 ? 112.075 107.763 139.276 1.00 23.51  ? 326 ARG R CZ  1 
ATOM   8108 N NH1 . ARG F 6 335 ? 113.127 107.032 139.612 1.00 23.51  ? 326 ARG R NH1 1 
ATOM   8109 N NH2 . ARG F 6 335 ? 110.887 107.467 139.793 1.00 23.51  ? 326 ARG R NH2 1 
ATOM   8110 N N   . VAL F 6 336 ? 117.477 111.214 135.144 1.00 22.05  ? 327 VAL R N   1 
ATOM   8111 C CA  . VAL F 6 336 ? 118.377 111.624 134.070 1.00 22.05  ? 327 VAL R CA  1 
ATOM   8112 C C   . VAL F 6 336 ? 119.244 110.452 133.630 1.00 22.05  ? 327 VAL R C   1 
ATOM   8113 O O   . VAL F 6 336 ? 119.493 110.260 132.431 1.00 22.05  ? 327 VAL R O   1 
ATOM   8114 C CB  . VAL F 6 336 ? 119.231 112.825 134.512 1.00 22.05  ? 327 VAL R CB  1 
ATOM   8115 C CG1 . VAL F 6 336 ? 120.225 113.192 133.424 1.00 22.05  ? 327 VAL R CG1 1 
ATOM   8116 C CG2 . VAL F 6 336 ? 118.343 114.008 134.851 1.00 22.05  ? 327 VAL R CG2 1 
ATOM   8117 N N   . ILE F 6 337 ? 119.729 109.655 134.585 1.00 27.24  ? 328 ILE R N   1 
ATOM   8118 C CA  . ILE F 6 337 ? 120.539 108.497 134.220 1.00 27.24  ? 328 ILE R CA  1 
ATOM   8119 C C   . ILE F 6 337 ? 119.709 107.502 133.422 1.00 27.24  ? 328 ILE R C   1 
ATOM   8120 O O   . ILE F 6 337 ? 120.198 106.894 132.462 1.00 27.24  ? 328 ILE R O   1 
ATOM   8121 C CB  . ILE F 6 337 ? 121.149 107.849 135.476 1.00 27.24  ? 328 ILE R CB  1 
ATOM   8122 C CG1 . ILE F 6 337 ? 122.358 108.654 135.961 1.00 27.24  ? 328 ILE R CG1 1 
ATOM   8123 C CG2 . ILE F 6 337 ? 121.550 106.408 135.196 1.00 27.24  ? 328 ILE R CG2 1 
ATOM   8124 C CD1 . ILE F 6 337 ? 123.544 108.645 135.015 1.00 27.24  ? 328 ILE R CD1 1 
ATOM   8125 N N   . CYS F 6 338 ? 118.444 107.312 133.803 1.00 26.87  ? 329 CYS R N   1 
ATOM   8126 C CA  . CYS F 6 338 ? 117.579 106.416 133.041 1.00 26.87  ? 329 CYS R CA  1 
ATOM   8127 C C   . CYS F 6 338 ? 117.444 106.889 131.598 1.00 26.87  ? 329 CYS R C   1 
ATOM   8128 O O   . CYS F 6 338 ? 117.551 106.095 130.653 1.00 26.87  ? 329 CYS R O   1 
ATOM   8129 C CB  . CYS F 6 338 ? 116.204 106.323 133.701 1.00 26.87  ? 329 CYS R CB  1 
ATOM   8130 S SG  . CYS F 6 338 ? 116.155 105.290 135.179 1.00 26.87  ? 329 CYS R SG  1 
ATOM   8131 N N   . ILE F 6 339 ? 117.210 108.188 131.411 1.00 25.48  ? 330 ILE R N   1 
ATOM   8132 C CA  . ILE F 6 339 ? 117.039 108.710 130.058 1.00 25.48  ? 330 ILE R CA  1 
ATOM   8133 C C   . ILE F 6 339 ? 118.324 108.543 129.255 1.00 25.48  ? 330 ILE R C   1 
ATOM   8134 O O   . ILE F 6 339 ? 118.291 108.165 128.077 1.00 25.48  ? 330 ILE R O   1 
ATOM   8135 C CB  . ILE F 6 339 ? 116.578 110.179 130.102 1.00 25.48  ? 330 ILE R CB  1 
ATOM   8136 C CG1 . ILE F 6 339 ? 115.060 110.240 130.276 1.00 25.48  ? 330 ILE R CG1 1 
ATOM   8137 C CG2 . ILE F 6 339 ? 116.988 110.913 128.835 1.00 25.48  ? 330 ILE R CG2 1 
ATOM   8138 C CD1 . ILE F 6 339 ? 114.536 111.611 130.631 1.00 25.48  ? 330 ILE R CD1 1 
ATOM   8139 N N   . VAL F 6 340 ? 119.472 108.834 129.869 1.00 29.06  ? 331 VAL R N   1 
ATOM   8140 C CA  . VAL F 6 340 ? 120.737 108.693 129.153 1.00 29.06  ? 331 VAL R CA  1 
ATOM   8141 C C   . VAL F 6 340 ? 120.965 107.239 128.763 1.00 29.06  ? 331 VAL R C   1 
ATOM   8142 O O   . VAL F 6 340 ? 121.466 106.944 127.671 1.00 29.06  ? 331 VAL R O   1 
ATOM   8143 C CB  . VAL F 6 340 ? 121.901 109.239 130.002 1.00 29.06  ? 331 VAL R CB  1 
ATOM   8144 C CG1 . VAL F 6 340 ? 123.229 108.661 129.527 1.00 29.06  ? 331 VAL R CG1 1 
ATOM   8145 C CG2 . VAL F 6 340 ? 121.927 110.760 129.953 1.00 29.06  ? 331 VAL R CG2 1 
ATOM   8146 N N   . VAL F 6 341 ? 120.614 106.309 129.651 1.00 33.80  ? 332 VAL R N   1 
ATOM   8147 C CA  . VAL F 6 341 ? 120.768 104.892 129.339 1.00 33.80  ? 332 VAL R CA  1 
ATOM   8148 C C   . VAL F 6 341 ? 119.897 104.516 128.150 1.00 33.80  ? 332 VAL R C   1 
ATOM   8149 O O   . VAL F 6 341 ? 120.332 103.790 127.249 1.00 33.80  ? 332 VAL R O   1 
ATOM   8150 C CB  . VAL F 6 341 ? 120.439 104.035 130.576 1.00 33.80  ? 332 VAL R CB  1 
ATOM   8151 C CG1 . VAL F 6 341 ? 120.081 102.613 130.166 1.00 33.80  ? 332 VAL R CG1 1 
ATOM   8152 C CG2 . VAL F 6 341 ? 121.609 104.033 131.544 1.00 33.80  ? 332 VAL R CG2 1 
ATOM   8153 N N   . SER F 6 342 ? 118.649 104.991 128.134 1.00 32.25  ? 333 SER R N   1 
ATOM   8154 C CA  . SER F 6 342 ? 117.775 104.694 127.002 1.00 32.25  ? 333 SER R CA  1 
ATOM   8155 C C   . SER F 6 342 ? 118.350 105.245 125.703 1.00 32.25  ? 333 SER R C   1 
ATOM   8156 O O   . SER F 6 342 ? 118.364 104.555 124.676 1.00 32.25  ? 333 SER R O   1 
ATOM   8157 C CB  . SER F 6 342 ? 116.378 105.261 127.249 1.00 32.25  ? 333 SER R CB  1 
ATOM   8158 O OG  . SER F 6 342 ? 115.604 104.381 128.044 1.00 32.25  ? 333 SER R OG  1 
ATOM   8159 N N   . LYS F 6 343 ? 118.839 106.488 125.730 1.00 31.82  ? 334 LYS R N   1 
ATOM   8160 C CA  . LYS F 6 343 ? 119.411 107.076 124.522 1.00 31.82  ? 334 LYS R CA  1 
ATOM   8161 C C   . LYS F 6 343 ? 120.615 106.278 124.039 1.00 31.82  ? 334 LYS R C   1 
ATOM   8162 O O   . LYS F 6 343 ? 120.759 106.024 122.838 1.00 31.82  ? 334 LYS R O   1 
ATOM   8163 C CB  . LYS F 6 343 ? 119.808 108.531 124.770 1.00 31.82  ? 334 LYS R CB  1 
ATOM   8164 C CG  . LYS F 6 343 ? 118.659 109.474 125.105 1.00 31.82  ? 334 LYS R CG  1 
ATOM   8165 C CD  . LYS F 6 343 ? 117.438 109.245 124.233 1.00 31.82  ? 334 LYS R CD  1 
ATOM   8166 C CE  . LYS F 6 343 ? 116.409 110.342 124.432 1.00 31.82  ? 334 LYS R CE  1 
ATOM   8167 N NZ  . LYS F 6 343 ? 115.022 109.859 124.202 1.00 31.82  ? 334 LYS R NZ  1 
ATOM   8168 N N   . LEU F 6 344 ? 121.496 105.878 124.958 1.00 40.27  ? 335 LEU R N   1 
ATOM   8169 C CA  . LEU F 6 344 ? 122.664 105.101 124.558 1.00 40.27  ? 335 LEU R CA  1 
ATOM   8170 C C   . LEU F 6 344 ? 122.255 103.752 123.983 1.00 40.27  ? 335 LEU R C   1 
ATOM   8171 O O   . LEU F 6 344 ? 122.828 103.293 122.989 1.00 40.27  ? 335 LEU R O   1 
ATOM   8172 C CB  . LEU F 6 344 ? 123.603 104.907 125.749 1.00 40.27  ? 335 LEU R CB  1 
ATOM   8173 C CG  . LEU F 6 344 ? 124.525 106.078 126.091 1.00 40.27  ? 335 LEU R CG  1 
ATOM   8174 C CD1 . LEU F 6 344 ? 125.259 105.804 127.391 1.00 40.27  ? 335 LEU R CD1 1 
ATOM   8175 C CD2 . LEU F 6 344 ? 125.514 106.345 124.968 1.00 40.27  ? 335 LEU R CD2 1 
ATOM   8176 N N   . LYS F 6 345 ? 121.270 103.096 124.601 1.00 45.07  ? 336 LYS R N   1 
ATOM   8177 C CA  . LYS F 6 345 ? 120.848 101.784 124.127 1.00 45.07  ? 336 LYS R CA  1 
ATOM   8178 C C   . LYS F 6 345 ? 120.232 101.868 122.738 1.00 45.07  ? 336 LYS R C   1 
ATOM   8179 O O   . LYS F 6 345 ? 120.508 101.022 121.879 1.00 45.07  ? 336 LYS R O   1 
ATOM   8180 C CB  . LYS F 6 345 ? 119.855 101.166 125.111 1.00 45.07  ? 336 LYS R CB  1 
ATOM   8181 C CG  . LYS F 6 345 ? 120.486 100.621 126.385 1.00 45.07  ? 336 LYS R CG  1 
ATOM   8182 C CD  . LYS F 6 345 ? 121.362 99.404  126.124 1.00 45.07  ? 336 LYS R CD  1 
ATOM   8183 C CE  . LYS F 6 345 ? 121.956 98.866  127.416 1.00 45.07  ? 336 LYS R CE  1 
ATOM   8184 N NZ  . LYS F 6 345 ? 122.028 97.380  127.426 1.00 45.07  ? 336 LYS R NZ  1 
ATOM   8185 N N   . ALA F 6 346 ? 119.395 102.880 122.495 1.00 45.65  ? 337 ALA R N   1 
ATOM   8186 C CA  . ALA F 6 346 ? 118.724 102.975 121.202 1.00 45.65  ? 337 ALA R CA  1 
ATOM   8187 C C   . ALA F 6 346 ? 119.726 103.142 120.065 1.00 45.65  ? 337 ALA R C   1 
ATOM   8188 O O   . ALA F 6 346 ? 119.608 102.485 119.025 1.00 45.65  ? 337 ALA R O   1 
ATOM   8189 C CB  . ALA F 6 346 ? 117.729 104.134 121.212 1.00 45.65  ? 337 ALA R CB  1 
ATOM   8190 N N   . ASN F 6 347 ? 120.716 104.009 120.244 1.00 46.59  ? 338 ASN R N   1 
ATOM   8191 C CA  . ASN F 6 347 ? 121.709 104.251 119.204 1.00 46.59  ? 338 ASN R CA  1 
ATOM   8192 C C   . ASN F 6 347 ? 122.936 103.369 119.405 1.00 46.59  ? 338 ASN R C   1 
ATOM   8193 O O   . ASN F 6 347 ? 123.265 102.543 118.554 1.00 46.59  ? 338 ASN R O   1 
ATOM   8194 C CB  . ASN F 6 347 ? 122.117 105.728 119.184 1.00 46.59  ? 338 ASN R CB  1 
ATOM   8195 C CG  . ASN F 6 347 ? 122.863 106.148 120.436 1.00 46.59  ? 338 ASN R CG  1 
ATOM   8196 O OD1 . ASN F 6 347 ? 122.913 105.413 121.423 1.00 46.59  ? 338 ASN R OD1 1 
ATOM   8197 N ND2 . ASN F 6 347 ? 123.452 107.338 120.401 1.00 46.59  ? 338 ASN R ND2 1 
ATOM   8198 N N   . ASP F 6 353 ? 131.354 98.758  125.060 1.00 76.04  ? 344 ASP R N   1 
ATOM   8199 C CA  . ASP F 6 353 ? 131.931 100.068 125.342 1.00 76.04  ? 344 ASP R CA  1 
ATOM   8200 C C   . ASP F 6 353 ? 130.867 101.041 125.843 1.00 76.04  ? 344 ASP R C   1 
ATOM   8201 O O   . ASP F 6 353 ? 131.172 102.179 126.195 1.00 76.04  ? 344 ASP R O   1 
ATOM   8202 C CB  . ASP F 6 353 ? 132.611 100.631 124.092 1.00 76.04  ? 344 ASP R CB  1 
ATOM   8203 N N   . ILE F 6 354 ? 129.613 100.583 125.871 1.00 56.93  ? 345 ILE R N   1 
ATOM   8204 C CA  . ILE F 6 354 ? 128.525 101.427 126.355 1.00 56.93  ? 345 ILE R CA  1 
ATOM   8205 C C   . ILE F 6 354 ? 128.738 101.782 127.822 1.00 56.93  ? 345 ILE R C   1 
ATOM   8206 O O   . ILE F 6 354 ? 128.542 102.932 128.236 1.00 56.93  ? 345 ILE R O   1 
ATOM   8207 C CB  . ILE F 6 354 ? 127.171 100.728 126.132 1.00 56.93  ? 345 ILE R CB  1 
ATOM   8208 C CG1 . ILE F 6 354 ? 126.019 101.651 126.527 1.00 56.93  ? 345 ILE R CG1 1 
ATOM   8209 C CG2 . ILE F 6 354 ? 127.091 99.431  126.926 1.00 56.93  ? 345 ILE R CG2 1 
ATOM   8210 C CD1 . ILE F 6 354 ? 124.671 101.180 126.036 1.00 56.93  ? 345 ILE R CD1 1 
ATOM   8211 N N   . LYS F 6 355 ? 129.147 100.800 128.630 1.00 58.10  ? 346 LYS R N   1 
ATOM   8212 C CA  . LYS F 6 355 ? 129.304 101.041 130.058 1.00 58.10  ? 346 LYS R CA  1 
ATOM   8213 C C   . LYS F 6 355 ? 130.377 102.082 130.340 1.00 58.10  ? 346 LYS R C   1 
ATOM   8214 O O   . LYS F 6 355 ? 130.258 102.839 131.305 1.00 58.10  ? 346 LYS R O   1 
ATOM   8215 C CB  . LYS F 6 355 ? 129.632 99.733  130.780 1.00 58.10  ? 346 LYS R CB  1 
ATOM   8216 N N   . CYS F 6 356 ? 131.426 102.141 129.520 1.00 56.98  ? 347 CYS R N   1 
ATOM   8217 C CA  . CYS F 6 356 ? 132.457 103.152 129.729 1.00 56.98  ? 347 CYS R CA  1 
ATOM   8218 C C   . CYS F 6 356 ? 131.870 104.555 129.645 1.00 56.98  ? 347 CYS R C   1 
ATOM   8219 O O   . CYS F 6 356 ? 132.062 105.382 130.548 1.00 56.98  ? 347 CYS R O   1 
ATOM   8220 C CB  . CYS F 6 356 ? 133.575 102.978 128.701 1.00 56.98  ? 347 CYS R CB  1 
ATOM   8221 S SG  . CYS F 6 356 ? 134.798 104.308 128.717 1.00 56.98  ? 347 CYS R SG  1 
ATOM   8222 N N   . ARG F 6 357 ? 131.136 104.839 128.567 1.00 44.78  ? 348 ARG R N   1 
ATOM   8223 C CA  . ARG F 6 357 ? 130.549 106.164 128.409 1.00 44.78  ? 348 ARG R CA  1 
ATOM   8224 C C   . ARG F 6 357 ? 129.483 106.425 129.463 1.00 44.78  ? 348 ARG R C   1 
ATOM   8225 O O   . ARG F 6 357 ? 129.358 107.549 129.962 1.00 44.78  ? 348 ARG R O   1 
ATOM   8226 C CB  . ARG F 6 357 ? 129.969 106.315 127.003 1.00 44.78  ? 348 ARG R CB  1 
ATOM   8227 C CG  . ARG F 6 357 ? 129.530 107.733 126.657 1.00 44.78  ? 348 ARG R CG  1 
ATOM   8228 C CD  . ARG F 6 357 ? 130.717 108.662 126.441 1.00 44.78  ? 348 ARG R CD  1 
ATOM   8229 N NE  . ARG F 6 357 ? 130.398 110.045 126.774 1.00 44.78  ? 348 ARG R NE  1 
ATOM   8230 C CZ  . ARG F 6 357 ? 131.247 111.058 126.666 1.00 44.78  ? 348 ARG R CZ  1 
ATOM   8231 N NH1 . ARG F 6 357 ? 132.486 110.879 126.238 1.00 44.78  ? 348 ARG R NH1 1 
ATOM   8232 N NH2 . ARG F 6 357 ? 130.844 112.281 126.997 1.00 44.78  ? 348 ARG R NH2 1 
ATOM   8233 N N   . LEU F 6 358 ? 128.699 105.402 129.817 1.00 41.86  ? 349 LEU R N   1 
ATOM   8234 C CA  . LEU F 6 358 ? 127.686 105.585 130.852 1.00 41.86  ? 349 LEU R CA  1 
ATOM   8235 C C   . LEU F 6 358 ? 128.323 105.947 132.188 1.00 41.86  ? 349 LEU R C   1 
ATOM   8236 O O   . LEU F 6 358 ? 127.841 106.839 132.897 1.00 41.86  ? 349 LEU R O   1 
ATOM   8237 C CB  . LEU F 6 358 ? 126.840 104.319 130.985 1.00 41.86  ? 349 LEU R CB  1 
ATOM   8238 C CG  . LEU F 6 358 ? 125.838 104.285 132.141 1.00 41.86  ? 349 LEU R CG  1 
ATOM   8239 C CD1 . LEU F 6 358 ? 124.997 105.547 132.171 1.00 41.86  ? 349 LEU R CD1 1 
ATOM   8240 C CD2 . LEU F 6 358 ? 124.951 103.059 132.028 1.00 41.86  ? 349 LEU R CD2 1 
ATOM   8241 N N   . ALA F 6 359 ? 129.413 105.265 132.549 1.00 42.62  ? 350 ALA R N   1 
ATOM   8242 C CA  . ALA F 6 359 ? 130.109 105.580 133.788 1.00 42.62  ? 350 ALA R CA  1 
ATOM   8243 C C   . ALA F 6 359 ? 130.705 106.978 133.740 1.00 42.62  ? 350 ALA R C   1 
ATOM   8244 O O   . ALA F 6 359 ? 130.653 107.717 134.731 1.00 42.62  ? 350 ALA R O   1 
ATOM   8245 C CB  . ALA F 6 359 ? 131.200 104.544 134.054 1.00 42.62  ? 350 ALA R CB  1 
ATOM   8246 N N   . LYS F 6 360 ? 131.282 107.361 132.600 1.00 38.08  ? 351 LYS R N   1 
ATOM   8247 C CA  . LYS F 6 360 ? 131.809 108.717 132.479 1.00 38.08  ? 351 LYS R CA  1 
ATOM   8248 C C   . LYS F 6 360 ? 130.704 109.741 132.697 1.00 38.08  ? 351 LYS R C   1 
ATOM   8249 O O   . LYS F 6 360 ? 130.885 110.724 133.425 1.00 38.08  ? 351 LYS R O   1 
ATOM   8250 C CB  . LYS F 6 360 ? 132.459 108.915 131.112 1.00 38.08  ? 351 LYS R CB  1 
ATOM   8251 C CG  . LYS F 6 360 ? 133.144 110.266 130.949 1.00 38.08  ? 351 LYS R CG  1 
ATOM   8252 C CD  . LYS F 6 360 ? 133.338 110.623 129.486 1.00 38.08  ? 351 LYS R CD  1 
ATOM   8253 C CE  . LYS F 6 360 ? 134.258 111.822 129.324 1.00 38.08  ? 351 LYS R CE  1 
ATOM   8254 N NZ  . LYS F 6 360 ? 133.717 113.035 129.998 1.00 38.08  ? 351 LYS R NZ  1 
ATOM   8255 N N   . SER F 6 361 ? 129.544 109.520 132.077 1.00 32.80  ? 352 SER R N   1 
ATOM   8256 C CA  . SER F 6 361 ? 128.438 110.459 132.219 1.00 32.80  ? 352 SER R CA  1 
ATOM   8257 C C   . SER F 6 361 ? 127.971 110.541 133.667 1.00 32.80  ? 352 SER R C   1 
ATOM   8258 O O   . SER F 6 361 ? 127.758 111.635 134.203 1.00 32.80  ? 352 SER R O   1 
ATOM   8259 C CB  . SER F 6 361 ? 127.284 110.046 131.308 1.00 32.80  ? 352 SER R CB  1 
ATOM   8260 O OG  . SER F 6 361 ? 126.413 109.149 131.972 1.00 32.80  ? 352 SER R OG  1 
ATOM   8261 N N   . THR F 6 362 ? 127.809 109.389 134.322 1.00 30.54  ? 353 THR R N   1 
ATOM   8262 C CA  . THR F 6 362 ? 127.345 109.399 135.706 1.00 30.54  ? 353 THR R CA  1 
ATOM   8263 C C   . THR F 6 362 ? 128.337 110.116 136.613 1.00 30.54  ? 353 THR R C   1 
ATOM   8264 O O   . THR F 6 362 ? 127.943 110.920 137.466 1.00 30.54  ? 353 THR R O   1 
ATOM   8265 C CB  . THR F 6 362 ? 127.114 107.969 136.196 1.00 30.54  ? 353 THR R CB  1 
ATOM   8266 O OG1 . THR F 6 362 ? 126.126 107.334 135.377 1.00 30.54  ? 353 THR R OG1 1 
ATOM   8267 C CG2 . THR F 6 362 ? 126.640 107.969 137.641 1.00 30.54  ? 353 THR R CG2 1 
ATOM   8268 N N   . LEU F 6 363 ? 129.631 109.835 136.445 1.00 29.26  ? 354 LEU R N   1 
ATOM   8269 C CA  . LEU F 6 363 ? 130.633 110.506 137.262 1.00 29.26  ? 354 LEU R CA  1 
ATOM   8270 C C   . LEU F 6 363 ? 130.605 112.009 137.029 1.00 29.26  ? 354 LEU R C   1 
ATOM   8271 O O   . LEU F 6 363 ? 130.683 112.793 137.980 1.00 29.26  ? 354 LEU R O   1 
ATOM   8272 C CB  . LEU F 6 363 ? 132.022 109.945 136.958 1.00 29.26  ? 354 LEU R CB  1 
ATOM   8273 C CG  . LEU F 6 363 ? 132.278 108.504 137.401 1.00 29.26  ? 354 LEU R CG  1 
ATOM   8274 C CD1 . LEU F 6 363 ? 133.646 108.044 136.927 1.00 29.26  ? 354 LEU R CD1 1 
ATOM   8275 C CD2 . LEU F 6 363 ? 132.159 108.368 138.910 1.00 29.26  ? 354 LEU R CD2 1 
ATOM   8276 N N   . THR F 6 364 ? 130.487 112.431 135.770 1.00 28.18  ? 355 THR R N   1 
ATOM   8277 C CA  . THR F 6 364 ? 130.427 113.860 135.495 1.00 28.18  ? 355 THR R CA  1 
ATOM   8278 C C   . THR F 6 364 ? 129.173 114.482 136.088 1.00 28.18  ? 355 THR R C   1 
ATOM   8279 O O   . THR F 6 364 ? 129.171 115.672 136.425 1.00 28.18  ? 355 THR R O   1 
ATOM   8280 C CB  . THR F 6 364 ? 130.475 114.117 133.989 1.00 28.18  ? 355 THR R CB  1 
ATOM   8281 O OG1 . THR F 6 364 ? 129.429 113.382 133.342 1.00 28.18  ? 355 THR R OG1 1 
ATOM   8282 C CG2 . THR F 6 364 ? 131.822 113.700 133.417 1.00 28.18  ? 355 THR R CG2 1 
ATOM   8283 N N   . LEU F 6 365 ? 128.101 113.703 136.221 1.00 24.73  ? 356 LEU R N   1 
ATOM   8284 C CA  . LEU F 6 365 ? 126.860 114.246 136.763 1.00 24.73  ? 356 LEU R CA  1 
ATOM   8285 C C   . LEU F 6 365 ? 126.875 114.329 138.283 1.00 24.73  ? 356 LEU R C   1 
ATOM   8286 O O   . LEU F 6 365 ? 126.179 115.176 138.852 1.00 24.73  ? 356 LEU R O   1 
ATOM   8287 C CB  . LEU F 6 365 ? 125.672 113.401 136.305 1.00 24.73  ? 356 LEU R CB  1 
ATOM   8288 C CG  . LEU F 6 365 ? 124.294 113.910 136.729 1.00 24.73  ? 356 LEU R CG  1 
ATOM   8289 C CD1 . LEU F 6 365 ? 124.038 115.297 136.170 1.00 24.73  ? 356 LEU R CD1 1 
ATOM   8290 C CD2 . LEU F 6 365 ? 123.222 112.946 136.272 1.00 24.73  ? 356 LEU R CD2 1 
ATOM   8291 N N   . ILE F 6 366 ? 127.630 113.463 138.954 1.00 24.64  ? 357 ILE R N   1 
ATOM   8292 C CA  . ILE F 6 366 ? 127.661 113.464 140.420 1.00 24.64  ? 357 ILE R CA  1 
ATOM   8293 C C   . ILE F 6 366 ? 127.882 114.873 140.960 1.00 24.64  ? 357 ILE R C   1 
ATOM   8294 O O   . ILE F 6 366 ? 127.014 115.397 141.672 1.00 24.64  ? 357 ILE R O   1 
ATOM   8295 C CB  . ILE F 6 366 ? 128.733 112.510 140.973 1.00 24.64  ? 357 ILE R CB  1 
ATOM   8296 C CG1 . ILE F 6 366 ? 128.426 111.065 140.590 1.00 24.64  ? 357 ILE R CG1 1 
ATOM   8297 C CG2 . ILE F 6 366 ? 128.829 112.648 142.488 1.00 24.64  ? 357 ILE R CG2 1 
ATOM   8298 C CD1 . ILE F 6 366 ? 129.561 110.104 140.871 1.00 24.64  ? 357 ILE R CD1 1 
ATOM   8299 N N   . PRO F 6 367 ? 129.008 115.527 140.665 1.00 21.54  ? 358 PRO R N   1 
ATOM   8300 C CA  . PRO F 6 367 ? 129.312 116.793 141.349 1.00 21.54  ? 358 PRO R CA  1 
ATOM   8301 C C   . PRO F 6 367 ? 128.316 117.905 141.075 1.00 21.54  ? 358 PRO R C   1 
ATOM   8302 O O   . PRO F 6 367 ? 128.239 118.847 141.872 1.00 21.54  ? 358 PRO R O   1 
ATOM   8303 C CB  . PRO F 6 367 ? 130.704 117.151 140.817 1.00 21.54  ? 358 PRO R CB  1 
ATOM   8304 C CG  . PRO F 6 367 ? 130.779 116.487 139.505 1.00 21.54  ? 358 PRO R CG  1 
ATOM   8305 C CD  . PRO F 6 367 ? 130.030 115.201 139.657 1.00 21.54  ? 358 PRO R CD  1 
ATOM   8306 N N   . LEU F 6 368 ? 127.560 117.844 139.978 1.00 22.24  ? 359 LEU R N   1 
ATOM   8307 C CA  . LEU F 6 368 ? 126.625 118.923 139.675 1.00 22.24  ? 359 LEU R CA  1 
ATOM   8308 C C   . LEU F 6 368 ? 125.449 118.924 140.644 1.00 22.24  ? 359 LEU R C   1 
ATOM   8309 O O   . LEU F 6 368 ? 125.075 119.973 141.180 1.00 22.24  ? 359 LEU R O   1 
ATOM   8310 C CB  . LEU F 6 368 ? 126.130 118.802 138.234 1.00 22.24  ? 359 LEU R CB  1 
ATOM   8311 C CG  . LEU F 6 368 ? 125.041 119.792 137.810 1.00 22.24  ? 359 LEU R CG  1 
ATOM   8312 C CD1 . LEU F 6 368 ? 125.496 121.224 138.023 1.00 22.24  ? 359 LEU R CD1 1 
ATOM   8313 C CD2 . LEU F 6 368 ? 124.650 119.567 136.359 1.00 22.24  ? 359 LEU R CD2 1 
ATOM   8314 N N   . LEU F 6 369 ? 124.849 117.759 140.878 1.00 20.93  ? 360 LEU R N   1 
ATOM   8315 C CA  . LEU F 6 369 ? 123.709 117.636 141.774 1.00 20.93  ? 360 LEU R CA  1 
ATOM   8316 C C   . LEU F 6 369 ? 124.105 117.204 143.178 1.00 20.93  ? 360 LEU R C   1 
ATOM   8317 O O   . LEU F 6 369 ? 123.232 117.090 144.044 1.00 20.93  ? 360 LEU R O   1 
ATOM   8318 C CB  . LEU F 6 369 ? 122.694 116.646 141.196 1.00 20.93  ? 360 LEU R CB  1 
ATOM   8319 C CG  . LEU F 6 369 ? 122.345 116.846 139.721 1.00 20.93  ? 360 LEU R CG  1 
ATOM   8320 C CD1 . LEU F 6 369 ? 121.276 115.863 139.294 1.00 20.93  ? 360 LEU R CD1 1 
ATOM   8321 C CD2 . LEU F 6 369 ? 121.888 118.269 139.460 1.00 20.93  ? 360 LEU R CD2 1 
ATOM   8322 N N   . GLY F 6 370 ? 125.387 116.958 143.425 1.00 23.43  ? 361 GLY R N   1 
ATOM   8323 C CA  . GLY F 6 370 ? 125.852 116.651 144.762 1.00 23.43  ? 361 GLY R CA  1 
ATOM   8324 C C   . GLY F 6 370 ? 125.164 115.454 145.382 1.00 23.43  ? 361 GLY R C   1 
ATOM   8325 O O   . GLY F 6 370 ? 124.753 115.505 146.545 1.00 23.43  ? 361 GLY R O   1 
ATOM   8326 N N   . THR F 6 371 ? 125.023 114.370 144.618 1.00 27.17  ? 362 THR R N   1 
ATOM   8327 C CA  . THR F 6 371 ? 124.364 113.176 145.130 1.00 27.17  ? 362 THR R CA  1 
ATOM   8328 C C   . THR F 6 371 ? 125.213 112.420 146.143 1.00 27.17  ? 362 THR R C   1 
ATOM   8329 O O   . THR F 6 371 ? 124.680 111.558 146.848 1.00 27.17  ? 362 THR R O   1 
ATOM   8330 C CB  . THR F 6 371 ? 123.998 112.240 143.979 1.00 27.17  ? 362 THR R CB  1 
ATOM   8331 O OG1 . THR F 6 371 ? 125.159 111.979 143.183 1.00 27.17  ? 362 THR R OG1 1 
ATOM   8332 C CG2 . THR F 6 371 ? 122.920 112.859 143.109 1.00 27.17  ? 362 THR R CG2 1 
ATOM   8333 N N   . HIS F 6 372 ? 126.510 112.720 146.237 1.00 30.36  ? 363 HIS R N   1 
ATOM   8334 C CA  . HIS F 6 372 ? 127.364 112.010 147.182 1.00 30.36  ? 363 HIS R CA  1 
ATOM   8335 C C   . HIS F 6 372 ? 126.852 112.141 148.610 1.00 30.36  ? 363 HIS R C   1 
ATOM   8336 O O   . HIS F 6 372 ? 127.099 111.261 149.441 1.00 30.36  ? 363 HIS R O   1 
ATOM   8337 C CB  . HIS F 6 372 ? 128.794 112.535 147.087 1.00 30.36  ? 363 HIS R CB  1 
ATOM   8338 C CG  . HIS F 6 372 ? 128.922 113.992 147.405 1.00 30.36  ? 363 HIS R CG  1 
ATOM   8339 N ND1 . HIS F 6 372 ? 129.004 114.469 148.695 1.00 30.36  ? 363 HIS R ND1 1 
ATOM   8340 C CD2 . HIS F 6 372 ? 128.981 115.077 146.597 1.00 30.36  ? 363 HIS R CD2 1 
ATOM   8341 C CE1 . HIS F 6 372 ? 129.108 115.786 148.668 1.00 30.36  ? 363 HIS R CE1 1 
ATOM   8342 N NE2 . HIS F 6 372 ? 129.096 116.179 147.408 1.00 30.36  ? 363 HIS R NE2 1 
ATOM   8343 N N   . GLU F 6 373 ? 126.142 113.228 148.916 1.00 34.10  ? 364 GLU R N   1 
ATOM   8344 C CA  . GLU F 6 373 ? 125.623 113.421 150.264 1.00 34.10  ? 364 GLU R CA  1 
ATOM   8345 C C   . GLU F 6 373 ? 124.584 112.376 150.638 1.00 34.10  ? 364 GLU R C   1 
ATOM   8346 O O   . GLU F 6 373 ? 124.340 112.164 151.830 1.00 34.10  ? 364 GLU R O   1 
ATOM   8347 C CB  . GLU F 6 373 ? 125.006 114.814 150.404 1.00 34.10  ? 364 GLU R CB  1 
ATOM   8348 C CG  . GLU F 6 373 ? 125.902 115.960 149.959 1.00 34.10  ? 364 GLU R CG  1 
ATOM   8349 C CD  . GLU F 6 373 ? 126.964 116.302 150.984 1.00 34.10  ? 364 GLU R CD  1 
ATOM   8350 O OE1 . GLU F 6 373 ? 127.548 115.368 151.568 1.00 34.10  ? 364 GLU R OE1 1 
ATOM   8351 O OE2 . GLU F 6 373 ? 127.213 117.506 151.202 1.00 34.10  ? 364 GLU R OE2 1 
ATOM   8352 N N   . VAL F 6 374 ? 123.967 111.715 149.654 1.00 35.97  ? 365 VAL R N   1 
ATOM   8353 C CA  . VAL F 6 374 ? 122.856 110.820 149.948 1.00 35.97  ? 365 VAL R CA  1 
ATOM   8354 C C   . VAL F 6 374 ? 123.315 109.540 150.632 1.00 35.97  ? 365 VAL R C   1 
ATOM   8355 O O   . VAL F 6 374 ? 122.494 108.842 151.238 1.00 35.97  ? 365 VAL R O   1 
ATOM   8356 C CB  . VAL F 6 374 ? 122.080 110.486 148.661 1.00 35.97  ? 365 VAL R CB  1 
ATOM   8357 C CG1 . VAL F 6 374 ? 120.792 109.749 148.996 1.00 35.97  ? 365 VAL R CG1 1 
ATOM   8358 C CG2 . VAL F 6 374 ? 121.779 111.753 147.869 1.00 35.97  ? 365 VAL R CG2 1 
ATOM   8359 N N   . ILE F 6 375 ? 124.606 109.209 150.561 1.00 46.73  ? 366 ILE R N   1 
ATOM   8360 C CA  . ILE F 6 375 ? 125.086 107.970 151.168 1.00 46.73  ? 366 ILE R CA  1 
ATOM   8361 C C   . ILE F 6 375 ? 124.853 107.993 152.674 1.00 46.73  ? 366 ILE R C   1 
ATOM   8362 O O   . ILE F 6 375 ? 124.353 107.024 153.259 1.00 46.73  ? 366 ILE R O   1 
ATOM   8363 C CB  . ILE F 6 375 ? 126.572 107.748 150.831 1.00 46.73  ? 366 ILE R CB  1 
ATOM   8364 C CG1 . ILE F 6 375 ? 126.725 107.352 149.362 1.00 46.73  ? 366 ILE R CG1 1 
ATOM   8365 C CG2 . ILE F 6 375 ? 127.165 106.674 151.731 1.00 46.73  ? 366 ILE R CG2 1 
ATOM   8366 C CD1 . ILE F 6 375 ? 128.157 107.355 148.871 1.00 46.73  ? 366 ILE R CD1 1 
ATOM   8367 N N   . PHE F 6 376 ? 125.206 109.103 153.324 1.00 53.98  ? 367 PHE R N   1 
ATOM   8368 C CA  . PHE F 6 376 ? 125.078 109.251 154.769 1.00 53.98  ? 367 PHE R CA  1 
ATOM   8369 C C   . PHE F 6 376 ? 124.036 110.296 155.154 1.00 53.98  ? 367 PHE R C   1 
ATOM   8370 O O   . PHE F 6 376 ? 124.027 110.763 156.297 1.00 53.98  ? 367 PHE R O   1 
ATOM   8371 C CB  . PHE F 6 376 ? 126.431 109.616 155.382 1.00 53.98  ? 367 PHE R CB  1 
ATOM   8372 C CG  . PHE F 6 376 ? 127.432 108.498 155.355 1.00 53.98  ? 367 PHE R CG  1 
ATOM   8373 C CD1 . PHE F 6 376 ? 127.269 107.383 156.160 1.00 53.98  ? 367 PHE R CD1 1 
ATOM   8374 C CD2 . PHE F 6 376 ? 128.543 108.567 154.533 1.00 53.98  ? 367 PHE R CD2 1 
ATOM   8375 C CE1 . PHE F 6 376 ? 128.192 106.356 156.139 1.00 53.98  ? 367 PHE R CE1 1 
ATOM   8376 C CE2 . PHE F 6 376 ? 129.468 107.542 154.508 1.00 53.98  ? 367 PHE R CE2 1 
ATOM   8377 C CZ  . PHE F 6 376 ? 129.294 106.435 155.312 1.00 53.98  ? 367 PHE R CZ  1 
ATOM   8378 N N   . ALA F 6 377 ? 123.156 110.672 154.225 1.00 51.91  ? 368 ALA R N   1 
ATOM   8379 C CA  . ALA F 6 377 ? 122.245 111.784 154.475 1.00 51.91  ? 368 ALA R CA  1 
ATOM   8380 C C   . ALA F 6 377 ? 121.323 111.498 155.653 1.00 51.91  ? 368 ALA R C   1 
ATOM   8381 O O   . ALA F 6 377 ? 121.128 112.352 156.525 1.00 51.91  ? 368 ALA R O   1 
ATOM   8382 C CB  . ALA F 6 377 ? 121.427 112.081 153.217 1.00 51.91  ? 368 ALA R CB  1 
ATOM   8383 N N   . PHE F 6 378 ? 120.751 110.297 155.700 1.00 66.54  ? 369 PHE R N   1 
ATOM   8384 C CA  . PHE F 6 378 ? 119.712 109.979 156.670 1.00 66.54  ? 369 PHE R CA  1 
ATOM   8385 C C   . PHE F 6 378 ? 120.252 109.382 157.963 1.00 66.54  ? 369 PHE R C   1 
ATOM   8386 O O   . PHE F 6 378 ? 119.459 109.022 158.838 1.00 66.54  ? 369 PHE R O   1 
ATOM   8387 C CB  . PHE F 6 378 ? 118.692 109.021 156.047 1.00 66.54  ? 369 PHE R CB  1 
ATOM   8388 C CG  . PHE F 6 378 ? 117.781 109.677 155.052 1.00 66.54  ? 369 PHE R CG  1 
ATOM   8389 C CD1 . PHE F 6 378 ? 118.235 110.001 153.785 1.00 66.54  ? 369 PHE R CD1 1 
ATOM   8390 C CD2 . PHE F 6 378 ? 116.471 109.977 155.385 1.00 66.54  ? 369 PHE R CD2 1 
ATOM   8391 C CE1 . PHE F 6 378 ? 117.399 110.608 152.867 1.00 66.54  ? 369 PHE R CE1 1 
ATOM   8392 C CE2 . PHE F 6 378 ? 115.630 110.584 154.471 1.00 66.54  ? 369 PHE R CE2 1 
ATOM   8393 C CZ  . PHE F 6 378 ? 116.095 110.899 153.211 1.00 66.54  ? 369 PHE R CZ  1 
ATOM   8394 N N   . VAL F 6 379 ? 121.572 109.267 158.112 1.00 66.05  ? 370 VAL R N   1 
ATOM   8395 C CA  . VAL F 6 379 ? 122.165 108.828 159.373 1.00 66.05  ? 370 VAL R CA  1 
ATOM   8396 C C   . VAL F 6 379 ? 122.075 110.011 160.333 1.00 66.05  ? 370 VAL R C   1 
ATOM   8397 O O   . VAL F 6 379 ? 122.891 110.932 160.283 1.00 66.05  ? 370 VAL R O   1 
ATOM   8398 C CB  . VAL F 6 379 ? 123.606 108.350 159.192 1.00 66.05  ? 370 VAL R CB  1 
ATOM   8399 C CG1 . VAL F 6 379 ? 124.242 108.050 160.543 1.00 66.05  ? 370 VAL R CG1 1 
ATOM   8400 C CG2 . VAL F 6 379 ? 123.646 107.124 158.294 1.00 66.05  ? 370 VAL R CG2 1 
ATOM   8401 N N   . MET F 6 380 ? 121.081 109.986 161.215 1.00 74.74  ? 371 MET R N   1 
ATOM   8402 C CA  . MET F 6 380 ? 120.786 111.138 162.049 1.00 74.74  ? 371 MET R CA  1 
ATOM   8403 C C   . MET F 6 380 ? 121.912 111.395 163.048 1.00 74.74  ? 371 MET R C   1 
ATOM   8404 O O   . MET F 6 380 ? 122.691 110.503 163.399 1.00 74.74  ? 371 MET R O   1 
ATOM   8405 C CB  . MET F 6 380 ? 119.466 110.937 162.792 1.00 74.74  ? 371 MET R CB  1 
ATOM   8406 C CG  . MET F 6 380 ? 118.323 110.460 161.909 1.00 74.74  ? 371 MET R CG  1 
ATOM   8407 S SD  . MET F 6 380 ? 118.110 111.470 160.431 1.00 74.74  ? 371 MET R SD  1 
ATOM   8408 C CE  . MET F 6 380 ? 117.116 112.813 161.074 1.00 74.74  ? 371 MET R CE  1 
ATOM   8409 N N   . ASP F 6 381 ? 121.988 112.646 163.505 1.00 73.12  ? 372 ASP R N   1 
ATOM   8410 C CA  . ASP F 6 381 ? 123.014 113.029 164.470 1.00 73.12  ? 372 ASP R CA  1 
ATOM   8411 C C   . ASP F 6 381 ? 122.844 112.274 165.782 1.00 73.12  ? 372 ASP R C   1 
ATOM   8412 O O   . ASP F 6 381 ? 123.832 111.872 166.408 1.00 73.12  ? 372 ASP R O   1 
ATOM   8413 C CB  . ASP F 6 381 ? 122.961 114.538 164.709 1.00 73.12  ? 372 ASP R CB  1 
ATOM   8414 C CG  . ASP F 6 381 ? 123.896 114.988 165.817 1.00 73.12  ? 372 ASP R CG  1 
ATOM   8415 O OD1 . ASP F 6 381 ? 124.840 114.242 166.149 1.00 73.12  ? 372 ASP R OD1 1 
ATOM   8416 O OD2 . ASP F 6 381 ? 123.683 116.093 166.359 1.00 73.12  ? 372 ASP R OD2 1 
ATOM   8417 N N   . GLU F 6 382 ? 121.598 112.067 166.213 1.00 81.42  ? 373 GLU R N   1 
ATOM   8418 C CA  . GLU F 6 382 ? 121.354 111.433 167.503 1.00 81.42  ? 373 GLU R CA  1 
ATOM   8419 C C   . GLU F 6 382 ? 121.913 110.018 167.571 1.00 81.42  ? 373 GLU R C   1 
ATOM   8420 O O   . GLU F 6 382 ? 122.093 109.490 168.674 1.00 81.42  ? 373 GLU R O   1 
ATOM   8421 C CB  . GLU F 6 382 ? 119.854 111.403 167.799 1.00 81.42  ? 373 GLU R CB  1 
ATOM   8422 C CG  . GLU F 6 382 ? 119.198 112.772 167.822 1.00 81.42  ? 373 GLU R CG  1 
ATOM   8423 C CD  . GLU F 6 382 ? 118.596 113.148 166.485 1.00 81.42  ? 373 GLU R CD  1 
ATOM   8424 O OE1 . GLU F 6 382 ? 119.310 113.057 165.465 1.00 81.42  ? 373 GLU R OE1 1 
ATOM   8425 O OE2 . GLU F 6 382 ? 117.407 113.530 166.453 1.00 81.42  ? 373 GLU R OE2 1 
ATOM   8426 N N   . HIS F 6 383 ? 122.191 109.393 166.431 1.00 83.16  ? 374 HIS R N   1 
ATOM   8427 C CA  . HIS F 6 383 ? 122.637 108.007 166.375 1.00 83.16  ? 374 HIS R CA  1 
ATOM   8428 C C   . HIS F 6 383 ? 123.971 107.887 165.649 1.00 83.16  ? 374 HIS R C   1 
ATOM   8429 O O   . HIS F 6 383 ? 124.169 107.001 164.816 1.00 83.16  ? 374 HIS R O   1 
ATOM   8430 C CB  . HIS F 6 383 ? 121.579 107.134 165.708 1.00 83.16  ? 374 HIS R CB  1 
ATOM   8431 C CG  . HIS F 6 383 ? 120.295 107.057 166.473 1.00 83.16  ? 374 HIS R CG  1 
ATOM   8432 N ND1 . HIS F 6 383 ? 120.155 106.302 167.618 1.00 83.16  ? 374 HIS R ND1 1 
ATOM   8433 C CD2 . HIS F 6 383 ? 119.093 107.645 166.261 1.00 83.16  ? 374 HIS R CD2 1 
ATOM   8434 C CE1 . HIS F 6 383 ? 118.922 106.426 168.077 1.00 83.16  ? 374 HIS R CE1 1 
ATOM   8435 N NE2 . HIS F 6 383 ? 118.257 107.235 167.271 1.00 83.16  ? 374 HIS R NE2 1 
ATOM   8436 N N   . ALA F 6 384 ? 124.906 108.784 165.957 1.00 77.85  ? 375 ALA R N   1 
ATOM   8437 C CA  . ALA F 6 384 ? 126.244 108.775 165.374 1.00 77.85  ? 375 ALA R CA  1 
ATOM   8438 C C   . ALA F 6 384 ? 127.259 108.662 166.504 1.00 77.85  ? 375 ALA R C   1 
ATOM   8439 O O   . ALA F 6 384 ? 127.539 109.649 167.192 1.00 77.85  ? 375 ALA R O   1 
ATOM   8440 C CB  . ALA F 6 384 ? 126.491 110.031 164.541 1.00 77.85  ? 375 ALA R CB  1 
ATOM   8441 N N   . ARG F 6 385 ? 127.810 107.464 166.691 1.00 76.25  ? 376 ARG R N   1 
ATOM   8442 C CA  . ARG F 6 385 ? 128.757 107.201 167.764 1.00 76.25  ? 376 ARG R CA  1 
ATOM   8443 C C   . ARG F 6 385 ? 129.928 106.403 167.210 1.00 76.25  ? 376 ARG R C   1 
ATOM   8444 O O   . ARG F 6 385 ? 129.915 105.949 166.063 1.00 76.25  ? 376 ARG R O   1 
ATOM   8445 C CB  . ARG F 6 385 ? 128.103 106.436 168.922 1.00 76.25  ? 376 ARG R CB  1 
ATOM   8446 C CG  . ARG F 6 385 ? 126.794 107.032 169.419 1.00 76.25  ? 376 ARG R CG  1 
ATOM   8447 C CD  . ARG F 6 385 ? 127.025 108.252 170.294 1.00 76.25  ? 376 ARG R CD  1 
ATOM   8448 N NE  . ARG F 6 385 ? 125.871 108.536 171.139 1.00 76.25  ? 376 ARG R NE  1 
ATOM   8449 C CZ  . ARG F 6 385 ? 124.716 109.012 170.694 1.00 76.25  ? 376 ARG R CZ  1 
ATOM   8450 N NH1 . ARG F 6 385 ? 124.526 109.281 169.412 1.00 76.25  ? 376 ARG R NH1 1 
ATOM   8451 N NH2 . ARG F 6 385 ? 123.726 109.224 171.556 1.00 76.25  ? 376 ARG R NH2 1 
ATOM   8452 N N   . GLY F 6 386 ? 130.949 106.234 168.044 1.00 73.84  ? 377 GLY R N   1 
ATOM   8453 C CA  . GLY F 6 386 ? 132.088 105.426 167.662 1.00 73.84  ? 377 GLY R CA  1 
ATOM   8454 C C   . GLY F 6 386 ? 132.785 105.981 166.435 1.00 73.84  ? 377 GLY R C   1 
ATOM   8455 O O   . GLY F 6 386 ? 132.843 107.193 166.206 1.00 73.84  ? 377 GLY R O   1 
ATOM   8456 N N   . THR F 6 387 ? 133.324 105.069 165.626 1.00 69.85  ? 378 THR R N   1 
ATOM   8457 C CA  . THR F 6 387 ? 133.994 105.453 164.391 1.00 69.85  ? 378 THR R CA  1 
ATOM   8458 C C   . THR F 6 387 ? 133.017 105.820 163.282 1.00 69.85  ? 378 THR R C   1 
ATOM   8459 O O   . THR F 6 387 ? 133.436 106.418 162.283 1.00 69.85  ? 378 THR R O   1 
ATOM   8460 C CB  . THR F 6 387 ? 134.907 104.319 163.917 1.00 69.85  ? 378 THR R CB  1 
ATOM   8461 O OG1 . THR F 6 387 ? 135.758 103.906 164.993 1.00 69.85  ? 378 THR R OG1 1 
ATOM   8462 C CG2 . THR F 6 387 ? 135.766 104.773 162.745 1.00 69.85  ? 378 THR R CG2 1 
ATOM   8463 N N   . LEU F 6 388 ? 131.734 105.479 163.429 1.00 71.48  ? 379 LEU R N   1 
ATOM   8464 C CA  . LEU F 6 388 ? 130.750 105.856 162.420 1.00 71.48  ? 379 LEU R CA  1 
ATOM   8465 C C   . LEU F 6 388 ? 130.659 107.370 162.284 1.00 71.48  ? 379 LEU R C   1 
ATOM   8466 O O   . LEU F 6 388 ? 130.616 107.899 161.166 1.00 71.48  ? 379 LEU R O   1 
ATOM   8467 C CB  . LEU F 6 388 ? 129.384 105.269 162.779 1.00 71.48  ? 379 LEU R CB  1 
ATOM   8468 C CG  . LEU F 6 388 ? 128.187 105.765 161.964 1.00 71.48  ? 379 LEU R CG  1 
ATOM   8469 C CD1 . LEU F 6 388 ? 128.381 105.472 160.485 1.00 71.48  ? 379 LEU R CD1 1 
ATOM   8470 C CD2 . LEU F 6 388 ? 126.901 105.136 162.471 1.00 71.48  ? 379 LEU R CD2 1 
ATOM   8471 N N   . ARG F 6 389 ? 130.624 108.084 163.411 1.00 66.09  ? 380 ARG R N   1 
ATOM   8472 C CA  . ARG F 6 389 ? 130.563 109.539 163.360 1.00 66.09  ? 380 ARG R CA  1 
ATOM   8473 C C   . ARG F 6 389 ? 131.802 110.115 162.691 1.00 66.09  ? 380 ARG R C   1 
ATOM   8474 O O   . ARG F 6 389 ? 131.703 111.032 161.866 1.00 66.09  ? 380 ARG R O   1 
ATOM   8475 C CB  . ARG F 6 389 ? 130.405 110.101 164.773 1.00 66.09  ? 380 ARG R CB  1 
ATOM   8476 C CG  . ARG F 6 389 ? 130.299 111.616 164.841 1.00 66.09  ? 380 ARG R CG  1 
ATOM   8477 C CD  . ARG F 6 389 ? 130.182 112.092 166.279 1.00 66.09  ? 380 ARG R CD  1 
ATOM   8478 N NE  . ARG F 6 389 ? 128.846 111.880 166.821 1.00 66.09  ? 380 ARG R NE  1 
ATOM   8479 C CZ  . ARG F 6 389 ? 127.889 112.799 166.858 1.00 66.09  ? 380 ARG R CZ  1 
ATOM   8480 N NH1 . ARG F 6 389 ? 128.077 114.017 166.377 1.00 66.09  ? 380 ARG R NH1 1 
ATOM   8481 N NH2 . ARG F 6 389 ? 126.711 112.486 167.391 1.00 66.09  ? 380 ARG R NH2 1 
ATOM   8482 N N   . PHE F 6 390 ? 132.979 109.589 163.031 1.00 60.25  ? 381 PHE R N   1 
ATOM   8483 C CA  . PHE F 6 390 ? 134.203 110.076 162.406 1.00 60.25  ? 381 PHE R CA  1 
ATOM   8484 C C   . PHE F 6 390 ? 134.173 109.857 160.902 1.00 60.25  ? 381 PHE R C   1 
ATOM   8485 O O   . PHE F 6 390 ? 134.532 110.753 160.129 1.00 60.25  ? 381 PHE R O   1 
ATOM   8486 C CB  . PHE F 6 390 ? 135.417 109.383 163.022 1.00 60.25  ? 381 PHE R CB  1 
ATOM   8487 C CG  . PHE F 6 390 ? 136.664 109.488 162.187 1.00 60.25  ? 381 PHE R CG  1 
ATOM   8488 C CD1 . PHE F 6 390 ? 137.443 110.630 162.224 1.00 60.25  ? 381 PHE R CD1 1 
ATOM   8489 C CD2 . PHE F 6 390 ? 137.056 108.442 161.368 1.00 60.25  ? 381 PHE R CD2 1 
ATOM   8490 C CE1 . PHE F 6 390 ? 138.588 110.728 161.459 1.00 60.25  ? 381 PHE R CE1 1 
ATOM   8491 C CE2 . PHE F 6 390 ? 138.200 108.536 160.602 1.00 60.25  ? 381 PHE R CE2 1 
ATOM   8492 C CZ  . PHE F 6 390 ? 138.966 109.679 160.647 1.00 60.25  ? 381 PHE R CZ  1 
ATOM   8493 N N   . ILE F 6 391 ? 133.747 108.670 160.464 1.00 60.65  ? 382 ILE R N   1 
ATOM   8494 C CA  . ILE F 6 391 ? 133.711 108.379 159.034 1.00 60.65  ? 382 ILE R CA  1 
ATOM   8495 C C   . ILE F 6 391 ? 132.727 109.301 158.329 1.00 60.65  ? 382 ILE R C   1 
ATOM   8496 O O   . ILE F 6 391 ? 133.013 109.831 157.249 1.00 60.65  ? 382 ILE R O   1 
ATOM   8497 C CB  . ILE F 6 391 ? 133.370 106.896 158.800 1.00 60.65  ? 382 ILE R CB  1 
ATOM   8498 C CG1 . ILE F 6 391 ? 134.602 106.024 159.048 1.00 60.65  ? 382 ILE R CG1 1 
ATOM   8499 C CG2 . ILE F 6 391 ? 132.842 106.682 157.389 1.00 60.65  ? 382 ILE R CG2 1 
ATOM   8500 C CD1 . ILE F 6 391 ? 135.594 106.015 157.899 1.00 60.65  ? 382 ILE R CD1 1 
ATOM   8501 N N   . LYS F 6 392 ? 131.546 109.498 158.920 1.00 55.41  ? 383 LYS R N   1 
ATOM   8502 C CA  . LYS F 6 392 ? 130.549 110.371 158.311 1.00 55.41  ? 383 LYS R CA  1 
ATOM   8503 C C   . LYS F 6 392 ? 131.080 111.792 158.170 1.00 55.41  ? 383 LYS R C   1 
ATOM   8504 O O   . LYS F 6 392 ? 130.959 112.413 157.105 1.00 55.41  ? 383 LYS R O   1 
ATOM   8505 C CB  . LYS F 6 392 ? 129.270 110.349 159.149 1.00 55.41  ? 383 LYS R CB  1 
ATOM   8506 C CG  . LYS F 6 392 ? 128.312 111.497 158.888 1.00 55.41  ? 383 LYS R CG  1 
ATOM   8507 C CD  . LYS F 6 392 ? 127.007 111.292 159.638 1.00 55.41  ? 383 LYS R CD  1 
ATOM   8508 C CE  . LYS F 6 392 ? 126.237 112.591 159.794 1.00 55.41  ? 383 LYS R CE  1 
ATOM   8509 N NZ  . LYS F 6 392 ? 125.631 113.044 158.513 1.00 55.41  ? 383 LYS R NZ  1 
ATOM   8510 N N   . LEU F 6 393 ? 131.677 112.322 159.241 1.00 51.38  ? 384 LEU R N   1 
ATOM   8511 C CA  . LEU F 6 393 ? 132.210 113.679 159.190 1.00 51.38  ? 384 LEU R CA  1 
ATOM   8512 C C   . LEU F 6 393 ? 133.304 113.791 158.138 1.00 51.38  ? 384 LEU R C   1 
ATOM   8513 O O   . LEU F 6 393 ? 133.313 114.727 157.334 1.00 51.38  ? 384 LEU R O   1 
ATOM   8514 C CB  . LEU F 6 393 ? 132.746 114.087 160.564 1.00 51.38  ? 384 LEU R CB  1 
ATOM   8515 C CG  . LEU F 6 393 ? 131.725 114.227 161.695 1.00 51.38  ? 384 LEU R CG  1 
ATOM   8516 C CD1 . LEU F 6 393 ? 132.423 114.643 162.979 1.00 51.38  ? 384 LEU R CD1 1 
ATOM   8517 C CD2 . LEU F 6 393 ? 130.633 115.218 161.334 1.00 51.38  ? 384 LEU R CD2 1 
ATOM   8518 N N   . PHE F 6 394 ? 134.234 112.835 158.123 1.00 47.28  ? 385 PHE R N   1 
ATOM   8519 C CA  . PHE F 6 394 ? 135.313 112.866 157.142 1.00 47.28  ? 385 PHE R CA  1 
ATOM   8520 C C   . PHE F 6 394 ? 134.756 112.878 155.724 1.00 47.28  ? 385 PHE R C   1 
ATOM   8521 O O   . PHE F 6 394 ? 135.099 113.749 154.912 1.00 47.28  ? 385 PHE R O   1 
ATOM   8522 C CB  . PHE F 6 394 ? 136.230 111.660 157.367 1.00 47.28  ? 385 PHE R CB  1 
ATOM   8523 C CG  . PHE F 6 394 ? 137.159 111.371 156.225 1.00 47.28  ? 385 PHE R CG  1 
ATOM   8524 C CD1 . PHE F 6 394 ? 136.760 110.561 155.174 1.00 47.28  ? 385 PHE R CD1 1 
ATOM   8525 C CD2 . PHE F 6 394 ? 138.440 111.892 156.211 1.00 47.28  ? 385 PHE R CD2 1 
ATOM   8526 C CE1 . PHE F 6 394 ? 137.618 110.289 154.127 1.00 47.28  ? 385 PHE R CE1 1 
ATOM   8527 C CE2 . PHE F 6 394 ? 139.302 111.623 155.166 1.00 47.28  ? 385 PHE R CE2 1 
ATOM   8528 C CZ  . PHE F 6 394 ? 138.889 110.820 154.124 1.00 47.28  ? 385 PHE R CZ  1 
ATOM   8529 N N   . THR F 6 395 ? 133.878 111.923 155.416 1.00 49.45  ? 386 THR R N   1 
ATOM   8530 C CA  . THR F 6 395 ? 133.301 111.830 154.080 1.00 49.45  ? 386 THR R CA  1 
ATOM   8531 C C   . THR F 6 395 ? 132.641 113.142 153.681 1.00 49.45  ? 386 THR R C   1 
ATOM   8532 O O   . THR F 6 395 ? 132.982 113.742 152.652 1.00 49.45  ? 386 THR R O   1 
ATOM   8533 C CB  . THR F 6 395 ? 132.288 110.684 154.037 1.00 49.45  ? 386 THR R CB  1 
ATOM   8534 O OG1 . THR F 6 395 ? 132.943 109.450 154.355 1.00 49.45  ? 386 THR R OG1 1 
ATOM   8535 C CG2 . THR F 6 395 ? 131.644 110.570 152.659 1.00 49.45  ? 386 THR R CG2 1 
ATOM   8536 N N   . GLU F 6 396 ? 131.673 113.594 154.482 1.00 46.34  ? 387 GLU R N   1 
ATOM   8537 C CA  . GLU F 6 396 ? 130.902 114.768 154.094 1.00 46.34  ? 387 GLU R CA  1 
ATOM   8538 C C   . GLU F 6 396 ? 131.790 115.997 153.973 1.00 46.34  ? 387 GLU R C   1 
ATOM   8539 O O   . GLU F 6 396 ? 131.698 116.737 152.989 1.00 46.34  ? 387 GLU R O   1 
ATOM   8540 C CB  . GLU F 6 396 ? 129.770 115.012 155.092 1.00 46.34  ? 387 GLU R CB  1 
ATOM   8541 C CG  . GLU F 6 396 ? 128.458 114.358 154.688 1.00 46.34  ? 387 GLU R CG  1 
ATOM   8542 C CD  . GLU F 6 396 ? 127.477 114.241 155.836 1.00 46.34  ? 387 GLU R CD  1 
ATOM   8543 O OE1 . GLU F 6 396 ? 127.927 114.131 156.995 1.00 46.34  ? 387 GLU R OE1 1 
ATOM   8544 O OE2 . GLU F 6 396 ? 126.255 114.256 155.580 1.00 46.34  ? 387 GLU R OE2 1 
ATOM   8545 N N   . LEU F 6 397 ? 132.671 116.226 154.949 1.00 43.65  ? 388 LEU R N   1 
ATOM   8546 C CA  . LEU F 6 397 ? 133.511 117.416 154.911 1.00 43.65  ? 388 LEU R CA  1 
ATOM   8547 C C   . LEU F 6 397 ? 134.399 117.419 153.674 1.00 43.65  ? 388 LEU R C   1 
ATOM   8548 O O   . LEU F 6 397 ? 134.438 118.408 152.933 1.00 43.65  ? 388 LEU R O   1 
ATOM   8549 C CB  . LEU F 6 397 ? 134.354 117.504 156.183 1.00 43.65  ? 388 LEU R CB  1 
ATOM   8550 C CG  . LEU F 6 397 ? 133.562 117.695 157.478 1.00 43.65  ? 388 LEU R CG  1 
ATOM   8551 C CD1 . LEU F 6 397 ? 134.437 117.399 158.679 1.00 43.65  ? 388 LEU R CD1 1 
ATOM   8552 C CD2 . LEU F 6 397 ? 132.999 119.101 157.563 1.00 43.65  ? 388 LEU R CD2 1 
ATOM   8553 N N   . SER F 6 398 ? 135.112 116.318 153.420 1.00 38.30  ? 389 SER R N   1 
ATOM   8554 C CA  . SER F 6 398 ? 136.032 116.300 152.288 1.00 38.30  ? 389 SER R CA  1 
ATOM   8555 C C   . SER F 6 398 ? 135.286 116.465 150.968 1.00 38.30  ? 389 SER R C   1 
ATOM   8556 O O   . SER F 6 398 ? 135.661 117.293 150.123 1.00 38.30  ? 389 SER R O   1 
ATOM   8557 C CB  . SER F 6 398 ? 136.837 115.002 152.293 1.00 38.30  ? 389 SER R CB  1 
ATOM   8558 O OG  . SER F 6 398 ? 137.639 114.911 153.456 1.00 38.30  ? 389 SER R OG  1 
ATOM   8559 N N   . PHE F 6 399 ? 134.219 115.684 150.771 1.00 36.05  ? 390 PHE R N   1 
ATOM   8560 C CA  . PHE F 6 399 ? 133.509 115.749 149.500 1.00 36.05  ? 390 PHE R CA  1 
ATOM   8561 C C   . PHE F 6 399 ? 132.880 117.119 149.285 1.00 36.05  ? 390 PHE R C   1 
ATOM   8562 O O   . PHE F 6 399 ? 132.944 117.668 148.180 1.00 36.05  ? 390 PHE R O   1 
ATOM   8563 C CB  . PHE F 6 399 ? 132.451 114.650 149.428 1.00 36.05  ? 390 PHE R CB  1 
ATOM   8564 C CG  . PHE F 6 399 ? 132.908 113.417 148.700 1.00 36.05  ? 390 PHE R CG  1 
ATOM   8565 C CD1 . PHE F 6 399 ? 133.308 113.490 147.375 1.00 36.05  ? 390 PHE R CD1 1 
ATOM   8566 C CD2 . PHE F 6 399 ? 132.945 112.190 149.337 1.00 36.05  ? 390 PHE R CD2 1 
ATOM   8567 C CE1 . PHE F 6 399 ? 133.729 112.364 146.701 1.00 36.05  ? 390 PHE R CE1 1 
ATOM   8568 C CE2 . PHE F 6 399 ? 133.368 111.058 148.668 1.00 36.05  ? 390 PHE R CE2 1 
ATOM   8569 C CZ  . PHE F 6 399 ? 133.761 111.147 147.347 1.00 36.05  ? 390 PHE R CZ  1 
ATOM   8570 N N   . THR F 6 400 ? 132.264 117.692 150.321 1.00 33.63  ? 391 THR R N   1 
ATOM   8571 C CA  . THR F 6 400 ? 131.650 119.005 150.166 1.00 33.63  ? 391 THR R CA  1 
ATOM   8572 C C   . THR F 6 400 ? 132.702 120.073 149.909 1.00 33.63  ? 391 THR R C   1 
ATOM   8573 O O   . THR F 6 400 ? 132.469 121.003 149.130 1.00 33.63  ? 391 THR R O   1 
ATOM   8574 C CB  . THR F 6 400 ? 130.825 119.348 151.404 1.00 33.63  ? 391 THR R CB  1 
ATOM   8575 O OG1 . THR F 6 400 ? 129.850 118.323 151.630 1.00 33.63  ? 391 THR R OG1 1 
ATOM   8576 C CG2 . THR F 6 400 ? 130.113 120.675 151.216 1.00 33.63  ? 391 THR R CG2 1 
ATOM   8577 N N   . SER F 6 401 ? 133.865 119.965 150.554 1.00 31.18  ? 392 SER R N   1 
ATOM   8578 C CA  . SER F 6 401 ? 134.920 120.941 150.321 1.00 31.18  ? 392 SER R CA  1 
ATOM   8579 C C   . SER F 6 401 ? 135.406 120.889 148.880 1.00 31.18  ? 392 SER R C   1 
ATOM   8580 O O   . SER F 6 401 ? 135.652 121.933 148.265 1.00 31.18  ? 392 SER R O   1 
ATOM   8581 C CB  . SER F 6 401 ? 136.077 120.702 151.289 1.00 31.18  ? 392 SER R CB  1 
ATOM   8582 O OG  . SER F 6 401 ? 136.575 119.383 151.168 1.00 31.18  ? 392 SER R OG  1 
ATOM   8583 N N   . PHE F 6 402 ? 135.551 119.687 148.321 1.00 27.58  ? 393 PHE R N   1 
ATOM   8584 C CA  . PHE F 6 402 ? 136.077 119.561 146.965 1.00 27.58  ? 393 PHE R CA  1 
ATOM   8585 C C   . PHE F 6 402 ? 135.006 119.637 145.880 1.00 27.58  ? 393 PHE R C   1 
ATOM   8586 O O   . PHE F 6 402 ? 135.353 119.685 144.692 1.00 27.58  ? 393 PHE R O   1 
ATOM   8587 C CB  . PHE F 6 402 ? 136.846 118.246 146.820 1.00 27.58  ? 393 PHE R CB  1 
ATOM   8588 C CG  . PHE F 6 402 ? 138.285 118.344 147.228 1.00 27.58  ? 393 PHE R CG  1 
ATOM   8589 C CD1 . PHE F 6 402 ? 138.630 118.492 148.557 1.00 27.58  ? 393 PHE R CD1 1 
ATOM   8590 C CD2 . PHE F 6 402 ? 139.290 118.291 146.283 1.00 27.58  ? 393 PHE R CD2 1 
ATOM   8591 C CE1 . PHE F 6 402 ? 139.951 118.583 148.936 1.00 27.58  ? 393 PHE R CE1 1 
ATOM   8592 C CE2 . PHE F 6 402 ? 140.611 118.381 146.658 1.00 27.58  ? 393 PHE R CE2 1 
ATOM   8593 C CZ  . PHE F 6 402 ? 140.942 118.528 147.986 1.00 27.58  ? 393 PHE R CZ  1 
ATOM   8594 N N   . GLN F 6 403 ? 133.725 119.654 146.254 1.00 24.75  ? 394 GLN R N   1 
ATOM   8595 C CA  . GLN F 6 403 ? 132.665 119.692 145.252 1.00 24.75  ? 394 GLN R CA  1 
ATOM   8596 C C   . GLN F 6 403 ? 132.703 120.983 144.444 1.00 24.75  ? 394 GLN R C   1 
ATOM   8597 O O   . GLN F 6 403 ? 132.419 120.977 143.240 1.00 24.75  ? 394 GLN R O   1 
ATOM   8598 C CB  . GLN F 6 403 ? 131.306 119.527 145.925 1.00 24.75  ? 394 GLN R CB  1 
ATOM   8599 C CG  . GLN F 6 403 ? 130.158 119.376 144.949 1.00 24.75  ? 394 GLN R CG  1 
ATOM   8600 C CD  . GLN F 6 403 ? 128.856 119.030 145.634 1.00 24.75  ? 394 GLN R CD  1 
ATOM   8601 O OE1 . GLN F 6 403 ? 128.847 118.543 146.761 1.00 24.75  ? 394 GLN R OE1 1 
ATOM   8602 N NE2 . GLN F 6 403 ? 127.747 119.280 144.954 1.00 24.75  ? 394 GLN R NE2 1 
ATOM   8603 N N   . GLY F 6 404 ? 133.022 122.105 145.087 1.00 23.28  ? 395 GLY R N   1 
ATOM   8604 C CA  . GLY F 6 404 ? 133.105 123.354 144.349 1.00 23.28  ? 395 GLY R CA  1 
ATOM   8605 C C   . GLY F 6 404 ? 134.139 123.298 143.242 1.00 23.28  ? 395 GLY R C   1 
ATOM   8606 O O   . GLY F 6 404 ? 133.867 123.670 142.098 1.00 23.28  ? 395 GLY R O   1 
ATOM   8607 N N   . LEU F 6 405 ? 135.342 122.818 143.569 1.00 24.71  ? 396 LEU R N   1 
ATOM   8608 C CA  . LEU F 6 405 ? 136.380 122.676 142.555 1.00 24.71  ? 396 LEU R CA  1 
ATOM   8609 C C   . LEU F 6 405 ? 135.953 121.696 141.475 1.00 24.71  ? 396 LEU R C   1 
ATOM   8610 O O   . LEU F 6 405 ? 136.174 121.939 140.282 1.00 24.71  ? 396 LEU R O   1 
ATOM   8611 C CB  . LEU F 6 405 ? 137.687 122.220 143.203 1.00 24.71  ? 396 LEU R CB  1 
ATOM   8612 C CG  . LEU F 6 405 ? 138.887 122.008 142.274 1.00 24.71  ? 396 LEU R CG  1 
ATOM   8613 C CD1 . LEU F 6 405 ? 140.181 122.249 143.029 1.00 24.71  ? 396 LEU R CD1 1 
ATOM   8614 C CD2 . LEU F 6 405 ? 138.892 120.616 141.667 1.00 24.71  ? 396 LEU R CD2 1 
ATOM   8615 N N   . MET F 6 406 ? 135.356 120.571 141.874 1.00 24.88  ? 397 MET R N   1 
ATOM   8616 C CA  . MET F 6 406 ? 134.898 119.596 140.891 1.00 24.88  ? 397 MET R CA  1 
ATOM   8617 C C   . MET F 6 406 ? 133.954 120.243 139.887 1.00 24.88  ? 397 MET R C   1 
ATOM   8618 O O   . MET F 6 406 ? 134.153 120.141 138.671 1.00 24.88  ? 397 MET R O   1 
ATOM   8619 C CB  . MET F 6 406 ? 134.207 118.430 141.596 1.00 24.88  ? 397 MET R CB  1 
ATOM   8620 C CG  . MET F 6 406 ? 135.151 117.458 142.279 1.00 24.88  ? 397 MET R CG  1 
ATOM   8621 S SD  . MET F 6 406 ? 134.439 115.808 142.438 1.00 24.88  ? 397 MET R SD  1 
ATOM   8622 C CE  . MET F 6 406 ? 133.355 116.034 143.845 1.00 24.88  ? 397 MET R CE  1 
ATOM   8623 N N   . VAL F 6 407 ? 132.923 120.926 140.382 1.00 21.92  ? 398 VAL R N   1 
ATOM   8624 C CA  . VAL F 6 407 ? 131.930 121.527 139.495 1.00 21.92  ? 398 VAL R CA  1 
ATOM   8625 C C   . VAL F 6 407 ? 132.581 122.582 138.611 1.00 21.92  ? 398 VAL R C   1 
ATOM   8626 O O   . VAL F 6 407 ? 132.342 122.636 137.399 1.00 21.92  ? 398 VAL R O   1 
ATOM   8627 C CB  . VAL F 6 407 ? 130.769 122.117 140.315 1.00 21.92  ? 398 VAL R CB  1 
ATOM   8628 C CG1 . VAL F 6 407 ? 129.870 122.958 139.432 1.00 21.92  ? 398 VAL R CG1 1 
ATOM   8629 C CG2 . VAL F 6 407 ? 129.975 121.007 140.977 1.00 21.92  ? 398 VAL R CG2 1 
ATOM   8630 N N   . ALA F 6 408 ? 133.414 123.441 139.205 1.00 26.03  ? 399 ALA R N   1 
ATOM   8631 C CA  . ALA F 6 408 ? 134.027 124.515 138.434 1.00 26.03  ? 399 ALA R CA  1 
ATOM   8632 C C   . ALA F 6 408 ? 134.855 123.958 137.283 1.00 26.03  ? 399 ALA R C   1 
ATOM   8633 O O   . ALA F 6 408 ? 134.665 124.343 136.124 1.00 26.03  ? 399 ALA R O   1 
ATOM   8634 C CB  . ALA F 6 408 ? 134.890 125.388 139.346 1.00 26.03  ? 399 ALA R CB  1 
ATOM   8635 N N   . ILE F 6 409 ? 135.768 123.031 137.581 1.00 27.16  ? 400 ILE R N   1 
ATOM   8636 C CA  . ILE F 6 409 ? 136.621 122.489 136.529 1.00 27.16  ? 400 ILE R CA  1 
ATOM   8637 C C   . ILE F 6 409 ? 135.783 121.745 135.498 1.00 27.16  ? 400 ILE R C   1 
ATOM   8638 O O   . ILE F 6 409 ? 136.024 121.852 134.291 1.00 27.16  ? 400 ILE R O   1 
ATOM   8639 C CB  . ILE F 6 409 ? 137.717 121.585 137.125 1.00 27.16  ? 400 ILE R CB  1 
ATOM   8640 C CG1 . ILE F 6 409 ? 138.705 121.166 136.035 1.00 27.16  ? 400 ILE R CG1 1 
ATOM   8641 C CG2 . ILE F 6 409 ? 137.114 120.349 137.764 1.00 27.16  ? 400 ILE R CG2 1 
ATOM   8642 C CD1 . ILE F 6 409 ? 139.868 120.346 136.545 1.00 27.16  ? 400 ILE R CD1 1 
ATOM   8643 N N   . LEU F 6 410 ? 134.785 120.983 135.951 1.00 24.87  ? 401 LEU R N   1 
ATOM   8644 C CA  . LEU F 6 410 ? 134.039 120.139 135.028 1.00 24.87  ? 401 LEU R CA  1 
ATOM   8645 C C   . LEU F 6 410 ? 133.218 120.971 134.051 1.00 24.87  ? 401 LEU R C   1 
ATOM   8646 O O   . LEU F 6 410 ? 133.161 120.653 132.859 1.00 24.87  ? 401 LEU R O   1 
ATOM   8647 C CB  . LEU F 6 410 ? 133.141 119.187 135.817 1.00 24.87  ? 401 LEU R CB  1 
ATOM   8648 C CG  . LEU F 6 410 ? 132.539 117.997 135.067 1.00 24.87  ? 401 LEU R CG  1 
ATOM   8649 C CD1 . LEU F 6 410 ? 132.269 116.883 136.055 1.00 24.87  ? 401 LEU R CD1 1 
ATOM   8650 C CD2 . LEU F 6 410 ? 131.260 118.343 134.321 1.00 24.87  ? 401 LEU R CD2 1 
ATOM   8651 N N   . TYR F 6 411 ? 132.575 122.037 134.531 1.00 24.95  ? 402 TYR R N   1 
ATOM   8652 C CA  . TYR F 6 411 ? 131.636 122.799 133.716 1.00 24.95  ? 402 TYR R CA  1 
ATOM   8653 C C   . TYR F 6 411 ? 132.192 124.129 133.226 1.00 24.95  ? 402 TYR R C   1 
ATOM   8654 O O   . TYR F 6 411 ? 131.441 124.915 132.641 1.00 24.95  ? 402 TYR R O   1 
ATOM   8655 C CB  . TYR F 6 411 ? 130.343 123.049 134.495 1.00 24.95  ? 402 TYR R CB  1 
ATOM   8656 C CG  . TYR F 6 411 ? 129.520 121.808 134.713 1.00 24.95  ? 402 TYR R CG  1 
ATOM   8657 C CD1 . TYR F 6 411 ? 128.639 121.360 133.744 1.00 24.95  ? 402 TYR R CD1 1 
ATOM   8658 C CD2 . TYR F 6 411 ? 129.620 121.083 135.889 1.00 24.95  ? 402 TYR R CD2 1 
ATOM   8659 C CE1 . TYR F 6 411 ? 127.884 120.226 133.937 1.00 24.95  ? 402 TYR R CE1 1 
ATOM   8660 C CE2 . TYR F 6 411 ? 128.870 119.948 136.092 1.00 24.95  ? 402 TYR R CE2 1 
ATOM   8661 C CZ  . TYR F 6 411 ? 128.005 119.523 135.112 1.00 24.95  ? 402 TYR R CZ  1 
ATOM   8662 O OH  . TYR F 6 411 ? 127.251 118.390 135.309 1.00 24.95  ? 402 TYR R OH  1 
ATOM   8663 N N   . CYS F 6 412 ? 133.471 124.412 133.450 1.00 34.59  ? 403 CYS R N   1 
ATOM   8664 C CA  . CYS F 6 412 ? 134.020 125.664 132.937 1.00 34.59  ? 403 CYS R CA  1 
ATOM   8665 C C   . CYS F 6 412 ? 135.292 125.490 132.122 1.00 34.59  ? 403 CYS R C   1 
ATOM   8666 O O   . CYS F 6 412 ? 135.476 126.200 131.132 1.00 34.59  ? 403 CYS R O   1 
ATOM   8667 C CB  . CYS F 6 412 ? 134.287 126.629 134.098 1.00 34.59  ? 403 CYS R CB  1 
ATOM   8668 S SG  . CYS F 6 412 ? 134.430 128.350 133.580 1.00 34.59  ? 403 CYS R SG  1 
ATOM   8669 N N   . PHE F 6 413 ? 136.175 124.569 132.507 1.00 35.01  ? 404 PHE R N   1 
ATOM   8670 C CA  . PHE F 6 413 ? 137.493 124.464 131.889 1.00 35.01  ? 404 PHE R CA  1 
ATOM   8671 C C   . PHE F 6 413 ? 137.523 123.431 130.767 1.00 35.01  ? 404 PHE R C   1 
ATOM   8672 O O   . PHE F 6 413 ? 137.821 123.767 129.618 1.00 35.01  ? 404 PHE R O   1 
ATOM   8673 C CB  . PHE F 6 413 ? 138.547 124.132 132.955 1.00 35.01  ? 404 PHE R CB  1 
ATOM   8674 C CG  . PHE F 6 413 ? 138.775 125.235 133.965 1.00 35.01  ? 404 PHE R CG  1 
ATOM   8675 C CD1 . PHE F 6 413 ? 137.935 126.338 134.033 1.00 35.01  ? 404 PHE R CD1 1 
ATOM   8676 C CD2 . PHE F 6 413 ? 139.831 125.158 134.854 1.00 35.01  ? 404 PHE R CD2 1 
ATOM   8677 C CE1 . PHE F 6 413 ? 138.152 127.336 134.960 1.00 35.01  ? 404 PHE R CE1 1 
ATOM   8678 C CE2 . PHE F 6 413 ? 140.048 126.155 135.786 1.00 35.01  ? 404 PHE R CE2 1 
ATOM   8679 C CZ  . PHE F 6 413 ? 139.207 127.244 135.837 1.00 35.01  ? 404 PHE R CZ  1 
ATOM   8680 N N   . VAL F 6 414 ? 137.213 122.170 131.078 1.00 37.62  ? 405 VAL R N   1 
ATOM   8681 C CA  . VAL F 6 414 ? 137.229 121.125 130.062 1.00 37.62  ? 405 VAL R CA  1 
ATOM   8682 C C   . VAL F 6 414 ? 136.085 121.254 129.071 1.00 37.62  ? 405 VAL R C   1 
ATOM   8683 O O   . VAL F 6 414 ? 136.080 120.555 128.052 1.00 37.62  ? 405 VAL R O   1 
ATOM   8684 C CB  . VAL F 6 414 ? 137.180 119.730 130.717 1.00 37.62  ? 405 VAL R CB  1 
ATOM   8685 C CG1 . VAL F 6 414 ? 138.267 119.600 131.775 1.00 37.62  ? 405 VAL R CG1 1 
ATOM   8686 C CG2 . VAL F 6 414 ? 135.804 119.463 131.313 1.00 37.62  ? 405 VAL R CG2 1 
ATOM   8687 N N   . ASN F 6 415 ? 135.121 122.129 129.341 1.00 44.04  ? 406 ASN R N   1 
ATOM   8688 C CA  . ASN F 6 415 ? 133.962 122.263 128.471 1.00 44.04  ? 406 ASN R CA  1 
ATOM   8689 C C   . ASN F 6 415 ? 134.409 122.603 127.054 1.00 44.04  ? 406 ASN R C   1 
ATOM   8690 O O   . ASN F 6 415 ? 135.243 123.488 126.848 1.00 44.04  ? 406 ASN R O   1 
ATOM   8691 C CB  . ASN F 6 415 ? 133.030 123.345 129.016 1.00 44.04  ? 406 ASN R CB  1 
ATOM   8692 C CG  . ASN F 6 415 ? 131.623 123.223 128.482 1.00 44.04  ? 406 ASN R CG  1 
ATOM   8693 O OD1 . ASN F 6 415 ? 131.321 122.331 127.694 1.00 44.04  ? 406 ASN R OD1 1 
ATOM   8694 N ND2 . ASN F 6 415 ? 130.749 124.128 128.909 1.00 44.04  ? 406 ASN R ND2 1 
ATOM   8695 N N   . ASN F 6 416 ? 133.847 121.895 126.071 1.00 49.15  ? 407 ASN R N   1 
ATOM   8696 C CA  . ASN F 6 416 ? 134.364 121.988 124.708 1.00 49.15  ? 407 ASN R CA  1 
ATOM   8697 C C   . ASN F 6 416 ? 134.196 123.389 124.129 1.00 49.15  ? 407 ASN R C   1 
ATOM   8698 O O   . ASN F 6 416 ? 135.106 123.902 123.465 1.00 49.15  ? 407 ASN R O   1 
ATOM   8699 C CB  . ASN F 6 416 ? 133.685 120.944 123.820 1.00 49.15  ? 407 ASN R CB  1 
ATOM   8700 C CG  . ASN F 6 416 ? 132.186 121.131 123.737 1.00 49.15  ? 407 ASN R CG  1 
ATOM   8701 O OD1 . ASN F 6 416 ? 131.645 122.107 124.247 1.00 49.15  ? 407 ASN R OD1 1 
ATOM   8702 N ND2 . ASN F 6 416 ? 131.507 120.189 123.094 1.00 49.15  ? 407 ASN R ND2 1 
ATOM   8703 N N   . GLU F 6 417 ? 133.044 124.027 124.356 1.00 55.45  ? 408 GLU R N   1 
ATOM   8704 C CA  . GLU F 6 417 ? 132.848 125.362 123.797 1.00 55.45  ? 408 GLU R CA  1 
ATOM   8705 C C   . GLU F 6 417 ? 133.840 126.353 124.389 1.00 55.45  ? 408 GLU R C   1 
ATOM   8706 O O   . GLU F 6 417 ? 134.286 127.276 123.701 1.00 55.45  ? 408 GLU R O   1 
ATOM   8707 C CB  . GLU F 6 417 ? 131.416 125.862 124.012 1.00 55.45  ? 408 GLU R CB  1 
ATOM   8708 C CG  . GLU F 6 417 ? 130.317 124.830 123.836 1.00 55.45  ? 408 GLU R CG  1 
ATOM   8709 C CD  . GLU F 6 417 ? 129.995 124.106 125.119 1.00 55.45  ? 408 GLU R CD  1 
ATOM   8710 O OE1 . GLU F 6 417 ? 130.850 124.122 126.024 1.00 55.45  ? 408 GLU R OE1 1 
ATOM   8711 O OE2 . GLU F 6 417 ? 128.896 123.523 125.222 1.00 55.45  ? 408 GLU R OE2 1 
ATOM   8712 N N   . VAL F 6 418 ? 134.191 126.189 125.665 1.00 51.55  ? 409 VAL R N   1 
ATOM   8713 C CA  . VAL F 6 418 ? 135.166 127.088 126.277 1.00 51.55  ? 409 VAL R CA  1 
ATOM   8714 C C   . VAL F 6 418 ? 136.521 126.948 125.594 1.00 51.55  ? 409 VAL R C   1 
ATOM   8715 O O   . VAL F 6 418 ? 137.186 127.946 125.288 1.00 51.55  ? 409 VAL R O   1 
ATOM   8716 C CB  . VAL F 6 418 ? 135.262 126.824 127.790 1.00 51.55  ? 409 VAL R CB  1 
ATOM   8717 C CG1 . VAL F 6 418 ? 136.407 127.618 128.395 1.00 51.55  ? 409 VAL R CG1 1 
ATOM   8718 C CG2 . VAL F 6 418 ? 133.951 127.176 128.471 1.00 51.55  ? 409 VAL R CG2 1 
ATOM   8719 N N   . GLN F 6 419 ? 136.957 125.711 125.349 1.00 54.91  ? 410 GLN R N   1 
ATOM   8720 C CA  . GLN F 6 419 ? 138.225 125.508 124.659 1.00 54.91  ? 410 GLN R CA  1 
ATOM   8721 C C   . GLN F 6 419 ? 138.173 126.062 123.243 1.00 54.91  ? 410 GLN R C   1 
ATOM   8722 O O   . GLN F 6 419 ? 139.146 126.657 122.765 1.00 54.91  ? 410 GLN R O   1 
ATOM   8723 C CB  . GLN F 6 419 ? 138.588 124.024 124.640 1.00 54.91  ? 410 GLN R CB  1 
ATOM   8724 C CG  . GLN F 6 419 ? 139.060 123.492 125.979 1.00 54.91  ? 410 GLN R CG  1 
ATOM   8725 C CD  . GLN F 6 419 ? 139.474 122.037 125.910 1.00 54.91  ? 410 GLN R CD  1 
ATOM   8726 O OE1 . GLN F 6 419 ? 139.351 121.393 124.868 1.00 54.91  ? 410 GLN R OE1 1 
ATOM   8727 N NE2 . GLN F 6 419 ? 139.970 121.509 127.023 1.00 54.91  ? 410 GLN R NE2 1 
ATOM   8728 N N   . LEU F 6 420 ? 137.051 125.867 122.548 1.00 60.88  ? 411 LEU R N   1 
ATOM   8729 C CA  . LEU F 6 420 ? 136.915 126.426 121.208 1.00 60.88  ? 411 LEU R CA  1 
ATOM   8730 C C   . LEU F 6 420 ? 137.010 127.946 121.240 1.00 60.88  ? 411 LEU R C   1 
ATOM   8731 O O   . LEU F 6 420 ? 137.657 128.556 120.380 1.00 60.88  ? 411 LEU R O   1 
ATOM   8732 C CB  . LEU F 6 420 ? 135.590 125.983 120.590 1.00 60.88  ? 411 LEU R CB  1 
ATOM   8733 C CG  . LEU F 6 420 ? 135.333 126.440 119.153 1.00 60.88  ? 411 LEU R CG  1 
ATOM   8734 C CD1 . LEU F 6 420 ? 136.372 125.860 118.208 1.00 60.88  ? 411 LEU R CD1 1 
ATOM   8735 C CD2 . LEU F 6 420 ? 133.931 126.048 118.717 1.00 60.88  ? 411 LEU R CD2 1 
ATOM   8736 N N   . GLU F 6 421 ? 136.362 128.573 122.224 1.00 59.17  ? 412 GLU R N   1 
ATOM   8737 C CA  . GLU F 6 421 ? 136.434 130.021 122.358 1.00 59.17  ? 412 GLU R CA  1 
ATOM   8738 C C   . GLU F 6 421 ? 137.865 130.474 122.601 1.00 59.17  ? 412 GLU R C   1 
ATOM   8739 O O   . GLU F 6 421 ? 138.324 131.453 122.002 1.00 59.17  ? 412 GLU R O   1 
ATOM   8740 C CB  . GLU F 6 421 ? 135.525 130.486 123.494 1.00 59.17  ? 412 GLU R CB  1 
ATOM   8741 C CG  . GLU F 6 421 ? 134.053 130.512 123.132 1.00 59.17  ? 412 GLU R CG  1 
ATOM   8742 C CD  . GLU F 6 421 ? 133.724 131.574 122.103 1.00 59.17  ? 412 GLU R CD  1 
ATOM   8743 O OE1 . GLU F 6 421 ? 134.081 132.750 122.326 1.00 59.17  ? 412 GLU R OE1 1 
ATOM   8744 O OE2 . GLU F 6 421 ? 133.110 131.234 121.070 1.00 59.17  ? 412 GLU R OE2 1 
ATOM   8745 N N   . PHE F 6 422 ? 138.589 129.771 123.473 1.00 59.47  ? 413 PHE R N   1 
ATOM   8746 C CA  . PHE F 6 422 ? 139.981 130.134 123.722 1.00 59.47  ? 413 PHE R CA  1 
ATOM   8747 C C   . PHE F 6 422 ? 140.815 130.006 122.454 1.00 59.47  ? 413 PHE R C   1 
ATOM   8748 O O   . PHE F 6 422 ? 141.615 130.894 122.130 1.00 59.47  ? 413 PHE R O   1 
ATOM   8749 C CB  . PHE F 6 422 ? 140.562 129.258 124.831 1.00 59.47  ? 413 PHE R CB  1 
ATOM   8750 C CG  . PHE F 6 422 ? 140.314 129.786 126.215 1.00 59.47  ? 413 PHE R CG  1 
ATOM   8751 C CD1 . PHE F 6 422 ? 140.845 130.999 126.615 1.00 59.47  ? 413 PHE R CD1 1 
ATOM   8752 C CD2 . PHE F 6 422 ? 139.552 129.064 127.118 1.00 59.47  ? 413 PHE R CD2 1 
ATOM   8753 C CE1 . PHE F 6 422 ? 140.618 131.484 127.887 1.00 59.47  ? 413 PHE R CE1 1 
ATOM   8754 C CE2 . PHE F 6 422 ? 139.323 129.544 128.393 1.00 59.47  ? 413 PHE R CE2 1 
ATOM   8755 C CZ  . PHE F 6 422 ? 139.857 130.755 128.777 1.00 59.47  ? 413 PHE R CZ  1 
ATOM   8756 N N   . ARG F 6 423 ? 140.638 128.908 121.717 1.00 66.58  ? 414 ARG R N   1 
ATOM   8757 C CA  . ARG F 6 423 ? 141.432 128.689 120.513 1.00 66.58  ? 414 ARG R CA  1 
ATOM   8758 C C   . ARG F 6 423 ? 141.152 129.763 119.470 1.00 66.58  ? 414 ARG R C   1 
ATOM   8759 O O   . ARG F 6 423 ? 142.080 130.312 118.863 1.00 66.58  ? 414 ARG R O   1 
ATOM   8760 C CB  . ARG F 6 423 ? 141.147 127.299 119.941 1.00 66.58  ? 414 ARG R CB  1 
ATOM   8761 C CG  . ARG F 6 423 ? 141.595 126.145 120.832 1.00 66.58  ? 414 ARG R CG  1 
ATOM   8762 C CD  . ARG F 6 423 ? 143.108 126.097 121.007 1.00 66.58  ? 414 ARG R CD  1 
ATOM   8763 N NE  . ARG F 6 423 ? 143.813 125.994 119.735 1.00 66.58  ? 414 ARG R NE  1 
ATOM   8764 C CZ  . ARG F 6 423 ? 145.131 126.053 119.602 1.00 66.58  ? 414 ARG R CZ  1 
ATOM   8765 N NH1 . ARG F 6 423 ? 145.926 126.213 120.648 1.00 66.58  ? 414 ARG R NH1 1 
ATOM   8766 N NH2 . ARG F 6 423 ? 145.667 125.948 118.388 1.00 66.58  ? 414 ARG R NH2 1 
ATOM   8767 N N   . LYS F 6 424 ? 139.876 130.086 119.249 1.00 65.82  ? 415 LYS R N   1 
ATOM   8768 C CA  . LYS F 6 424 ? 139.563 131.093 118.240 1.00 65.82  ? 415 LYS R CA  1 
ATOM   8769 C C   . LYS F 6 424 ? 139.982 132.485 118.694 1.00 65.82  ? 415 LYS R C   1 
ATOM   8770 O O   . LYS F 6 424 ? 140.380 133.306 117.862 1.00 65.82  ? 415 LYS R O   1 
ATOM   8771 C CB  . LYS F 6 424 ? 138.075 131.069 117.883 1.00 65.82  ? 415 LYS R CB  1 
ATOM   8772 C CG  . LYS F 6 424 ? 137.110 131.207 119.043 1.00 65.82  ? 415 LYS R CG  1 
ATOM   8773 C CD  . LYS F 6 424 ? 135.830 130.425 118.779 1.00 65.82  ? 415 LYS R CD  1 
ATOM   8774 C CE  . LYS F 6 424 ? 135.012 131.053 117.663 1.00 65.82  ? 415 LYS R CE  1 
ATOM   8775 N NZ  . LYS F 6 424 ? 133.633 130.495 117.597 1.00 65.82  ? 415 LYS R NZ  1 
ATOM   8776 N N   . SER F 6 425 ? 139.918 132.773 119.995 1.00 64.59  ? 416 SER R N   1 
ATOM   8777 C CA  . SER F 6 425 ? 140.427 134.049 120.482 1.00 64.59  ? 416 SER R CA  1 
ATOM   8778 C C   . SER F 6 425 ? 141.924 134.164 120.237 1.00 64.59  ? 416 SER R C   1 
ATOM   8779 O O   . SER F 6 425 ? 142.414 135.218 119.817 1.00 64.59  ? 416 SER R O   1 
ATOM   8780 C CB  . SER F 6 425 ? 140.114 134.208 121.968 1.00 64.59  ? 416 SER R CB  1 
ATOM   8781 O OG  . SER F 6 425 ? 140.574 135.457 122.451 1.00 64.59  ? 416 SER R OG  1 
ATOM   8782 N N   . TRP F 6 426 ? 142.671 133.088 120.491 1.00 69.40  ? 417 TRP R N   1 
ATOM   8783 C CA  . TRP F 6 426 ? 144.103 133.108 120.210 1.00 69.40  ? 417 TRP R CA  1 
ATOM   8784 C C   . TRP F 6 426 ? 144.367 133.283 118.720 1.00 69.40  ? 417 TRP R C   1 
ATOM   8785 O O   . TRP F 6 426 ? 145.275 134.023 118.322 1.00 69.40  ? 417 TRP R O   1 
ATOM   8786 C CB  . TRP F 6 426 ? 144.753 131.825 120.723 1.00 69.40  ? 417 TRP R CB  1 
ATOM   8787 C CG  . TRP F 6 426 ? 146.234 131.782 120.520 1.00 69.40  ? 417 TRP R CG  1 
ATOM   8788 C CD1 . TRP F 6 426 ? 147.192 132.240 121.376 1.00 69.40  ? 417 TRP R CD1 1 
ATOM   8789 C CD2 . TRP F 6 426 ? 146.930 131.250 119.387 1.00 69.40  ? 417 TRP R CD2 1 
ATOM   8790 N NE1 . TRP F 6 426 ? 148.441 132.027 120.847 1.00 69.40  ? 417 TRP R NE1 1 
ATOM   8791 C CE2 . TRP F 6 426 ? 148.308 131.421 119.626 1.00 69.40  ? 417 TRP R CE2 1 
ATOM   8792 C CE3 . TRP F 6 426 ? 146.522 130.646 118.194 1.00 69.40  ? 417 TRP R CE3 1 
ATOM   8793 C CZ2 . TRP F 6 426 ? 149.279 131.009 118.717 1.00 69.40  ? 417 TRP R CZ2 1 
ATOM   8794 C CZ3 . TRP F 6 426 ? 147.488 130.238 117.293 1.00 69.40  ? 417 TRP R CZ3 1 
ATOM   8795 C CH2 . TRP F 6 426 ? 148.851 130.421 117.559 1.00 69.40  ? 417 TRP R CH2 1 
ATOM   8796 N N   . GLU F 6 427 ? 143.584 132.605 117.878 1.00 71.15  ? 418 GLU R N   1 
ATOM   8797 C CA  . GLU F 6 427 ? 143.767 132.741 116.437 1.00 71.15  ? 418 GLU R CA  1 
ATOM   8798 C C   . GLU F 6 427 ? 143.496 134.170 115.981 1.00 71.15  ? 418 GLU R C   1 
ATOM   8799 O O   . GLU F 6 427 ? 144.222 134.710 115.140 1.00 71.15  ? 418 GLU R O   1 
ATOM   8800 C CB  . GLU F 6 427 ? 142.858 131.759 115.698 1.00 71.15  ? 418 GLU R CB  1 
ATOM   8801 C CG  . GLU F 6 427 ? 143.469 130.379 115.502 1.00 71.15  ? 418 GLU R CG  1 
ATOM   8802 C CD  . GLU F 6 427 ? 144.725 130.409 114.653 1.00 71.15  ? 418 GLU R CD  1 
ATOM   8803 O OE1 . GLU F 6 427 ? 144.957 131.428 113.970 1.00 71.15  ? 418 GLU R OE1 1 
ATOM   8804 O OE2 . GLU F 6 427 ? 145.482 129.416 114.672 1.00 71.15  ? 418 GLU R OE2 1 
ATOM   8805 N N   . ARG F 6 428 ? 142.448 134.797 116.520 1.00 62.71  ? 419 ARG R N   1 
ATOM   8806 C CA  . ARG F 6 428 ? 142.181 136.196 116.200 1.00 62.71  ? 419 ARG R CA  1 
ATOM   8807 C C   . ARG F 6 428 ? 143.318 137.089 116.676 1.00 62.71  ? 419 ARG R C   1 
ATOM   8808 O O   . ARG F 6 428 ? 143.731 138.014 115.968 1.00 62.71  ? 419 ARG R O   1 
ATOM   8809 C CB  . ARG F 6 428 ? 140.858 136.634 116.823 1.00 62.71  ? 419 ARG R CB  1 
ATOM   8810 C CG  . ARG F 6 428 ? 139.630 136.007 116.183 1.00 62.71  ? 419 ARG R CG  1 
ATOM   8811 C CD  . ARG F 6 428 ? 138.355 136.516 116.833 1.00 62.71  ? 419 ARG R CD  1 
ATOM   8812 N NE  . ARG F 6 428 ? 137.305 135.504 116.859 1.00 62.71  ? 419 ARG R NE  1 
ATOM   8813 C CZ  . ARG F 6 428 ? 136.235 135.553 117.642 1.00 62.71  ? 419 ARG R CZ  1 
ATOM   8814 N NH1 . ARG F 6 428 ? 136.038 136.554 118.484 1.00 62.71  ? 419 ARG R NH1 1 
ATOM   8815 N NH2 . ARG F 6 428 ? 135.339 134.573 117.578 1.00 62.71  ? 419 ARG R NH2 1 
ATOM   8816 N N   . TRP F 6 429 ? 143.833 136.833 117.881 1.00 71.39  ? 420 TRP R N   1 
ATOM   8817 C CA  . TRP F 6 429 ? 144.985 137.583 118.365 1.00 71.39  ? 420 TRP R CA  1 
ATOM   8818 C C   . TRP F 6 429 ? 146.166 137.464 117.414 1.00 71.39  ? 420 TRP R C   1 
ATOM   8819 O O   . TRP F 6 429 ? 146.902 138.436 117.213 1.00 71.39  ? 420 TRP R O   1 
ATOM   8820 C CB  . TRP F 6 429 ? 145.384 137.090 119.757 1.00 71.39  ? 420 TRP R CB  1 
ATOM   8821 C CG  . TRP F 6 429 ? 144.848 137.926 120.874 1.00 71.39  ? 420 TRP R CG  1 
ATOM   8822 C CD1 . TRP F 6 429 ? 143.810 137.617 121.702 1.00 71.39  ? 420 TRP R CD1 1 
ATOM   8823 C CD2 . TRP F 6 429 ? 145.332 139.206 121.295 1.00 71.39  ? 420 TRP R CD2 1 
ATOM   8824 N NE1 . TRP F 6 429 ? 143.613 138.629 122.611 1.00 71.39  ? 420 TRP R NE1 1 
ATOM   8825 C CE2 . TRP F 6 429 ? 144.536 139.616 122.382 1.00 71.39  ? 420 TRP R CE2 1 
ATOM   8826 C CE3 . TRP F 6 429 ? 146.360 140.046 120.856 1.00 71.39  ? 420 TRP R CE3 1 
ATOM   8827 C CZ2 . TRP F 6 429 ? 144.735 140.829 123.037 1.00 71.39  ? 420 TRP R CZ2 1 
ATOM   8828 C CZ3 . TRP F 6 429 ? 146.555 141.250 121.508 1.00 71.39  ? 420 TRP R CZ3 1 
ATOM   8829 C CH2 . TRP F 6 429 ? 145.747 141.630 122.586 1.00 71.39  ? 420 TRP R CH2 1 
ATOM   8830 N N   . ARG F 6 430 ? 146.363 136.287 116.826 1.00 73.39  ? 421 ARG R N   1 
ATOM   8831 C CA  . ARG F 6 430 ? 147.477 136.066 115.914 1.00 73.39  ? 421 ARG R CA  1 
ATOM   8832 C C   . ARG F 6 430 ? 147.165 136.456 114.476 1.00 73.39  ? 421 ARG R C   1 
ATOM   8833 O O   . ARG F 6 430 ? 148.067 136.408 113.632 1.00 73.39  ? 421 ARG R O   1 
ATOM   8834 C CB  . ARG F 6 430 ? 147.908 134.595 115.958 1.00 73.39  ? 421 ARG R CB  1 
ATOM   8835 C CG  . ARG F 6 430 ? 148.555 134.158 117.272 1.00 73.39  ? 421 ARG R CG  1 
ATOM   8836 C CD  . ARG F 6 430 ? 149.583 135.160 117.785 1.00 73.39  ? 421 ARG R CD  1 
ATOM   8837 N NE  . ARG F 6 430 ? 148.975 136.222 118.580 1.00 73.39  ? 421 ARG R NE  1 
ATOM   8838 C CZ  . ARG F 6 430 ? 149.650 137.211 119.149 1.00 73.39  ? 421 ARG R CZ  1 
ATOM   8839 N NH1 . ARG F 6 430 ? 150.965 137.307 119.036 1.00 73.39  ? 421 ARG R NH1 1 
ATOM   8840 N NH2 . ARG F 6 430 ? 148.990 138.128 119.850 1.00 73.39  ? 421 ARG R NH2 1 
ATOM   8841 N N   . LEU F 6 431 ? 145.922 136.834 114.171 1.00 58.73  ? 422 LEU R N   1 
ATOM   8842 C CA  . LEU F 6 431 ? 145.615 137.328 112.831 1.00 58.73  ? 422 LEU R CA  1 
ATOM   8843 C C   . LEU F 6 431 ? 146.355 138.628 112.542 1.00 58.73  ? 422 LEU R C   1 
ATOM   8844 O O   . LEU F 6 431 ? 146.856 138.827 111.429 1.00 58.73  ? 422 LEU R O   1 
ATOM   8845 C CB  . LEU F 6 431 ? 144.107 137.532 112.672 1.00 58.73  ? 422 LEU R CB  1 
ATOM   8846 C CG  . LEU F 6 431 ? 143.288 136.351 112.140 1.00 58.73  ? 422 LEU R CG  1 
ATOM   8847 C CD1 . LEU F 6 431 ? 141.811 136.712 112.104 1.00 58.73  ? 422 LEU R CD1 1 
ATOM   8848 C CD2 . LEU F 6 431 ? 143.763 135.923 110.761 1.00 58.73  ? 422 LEU R CD2 1 
ATOM   8849 N N   . GLU F 6 432 ? 146.431 139.521 113.524 1.00 68.04  ? 423 GLU R N   1 
ATOM   8850 C CA  . GLU F 6 432 ? 147.110 140.799 113.350 1.00 68.04  ? 423 GLU R CA  1 
ATOM   8851 C C   . GLU F 6 432 ? 148.545 140.590 112.881 1.00 68.04  ? 423 GLU R C   1 
ATOM   8852 O O   . GLU F 6 432 ? 149.228 139.672 113.335 0.00 68.04  ? 423 GLU R O   1 
ATOM   8853 C CB  . GLU F 6 432 ? 147.090 141.598 114.656 1.00 68.04  ? 423 GLU R CB  1 
ATOM   8854 C CG  . GLU F 6 432 ? 148.117 141.147 115.686 1.00 68.04  ? 423 GLU R CG  1 
ATOM   8855 C CD  . GLU F 6 432 ? 147.986 141.890 117.000 1.00 68.04  ? 423 GLU R CD  1 
ATOM   8856 O OE1 . GLU F 6 432 ? 147.053 142.710 117.131 1.00 68.04  ? 423 GLU R OE1 1 
ATOM   8857 O OE2 . GLU F 6 432 ? 148.818 141.657 117.902 1.00 68.04  ? 423 GLU R OE2 1 
# 
