data_9E6M
# 
_entry.id   9E6M 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9E6M         pdb_00009e6m 10.2210/pdb9e6m/pdb 
WWPDB D_1000289414 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9E6M 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        'wild type malic enzyme' 
_pdbx_database_related.db_id          5OU5 
_pdbx_database_related.content_type   unspecified 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
9  alvarez@cefobi-conicet.gov.ar Clarisa  Alvarez E 'principal investigator/group leader' 0000-0001-7279-6974 
10 vero.maurino@uni-bonn.de      Veronica Maurino G 'principal investigator/group leader' 0000-0002-3124-1451 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Klinke, S.'      1 0000-0002-8777-0870 
'Schneberger, N.' 2 0000-0002-4703-5425 
'Boehm, J.M.'     3 0009-0008-6498-5802 
'Willms, S.'      4 0009-0008-3522-7156 
'Hagelueken, G.'  5 0000-0001-8781-5664 
'Geyer, M.'       6 0000-0002-7718-5002 
'Maurino, V.'     7 0000-0002-3124-1451 
'Alvarez, C.E.'   8 0000-0001-7279-6974 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Crystal structure of the G200R mutant from the maize chloroplastic photosynthetic NADP(+)-dependent malic enzyme' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Klinke, S.'      1 0000-0002-8777-0870 
primary 'Schneberger, N.' 2 0000-0002-4703-5425 
primary 'Boehm, J.M.'     3 0009-0008-6498-5802 
primary 'Willms, S.'      4 0009-0008-3522-7156 
primary 'Hagelueken, G.'  5 0000-0001-8781-5664 
primary 'Geyer, M.'       6 0000-0002-7718-5002 
primary 'Maurino, V.'     7 0000-0002-3124-1451 
primary 'Alvarez, C.E.'   8 0000-0001-7279-6974 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Malic enzyme' 63744.512 4  ? G200R ? ? 
2 non-polymer syn 'PYRUVIC ACID' 88.062    6  ? ?     ? ? 
3 water       nat water          18.015    29 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;HAMVSNAETETEKEQEEAAAASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKF
MNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFRRPQGLYVSLKDKGKVLEVLR
NWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEKLLNDEFYIGLRQKRATG
EEYDELIEEFMSAVKQFYGEKVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTYL
FLGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWAHEHEPLKTLYDAVQSIKPTVL
IGTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSECTAEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYI
FPGLGLGLVISGAVRVHEDMLLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAAKAYELGLATRLPPPSDLV
KYAENCMYTPVYRNYR
;
_entity_poly.pdbx_seq_one_letter_code_can   
;HAMVSNAETETEKEQEEAAAASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKF
MNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFRRPQGLYVSLKDKGKVLEVLR
NWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEKLLNDEFYIGLRQKRATG
EEYDELIEEFMSAVKQFYGEKVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTYL
FLGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWAHEHEPLKTLYDAVQSIKPTVL
IGTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSECTAEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYI
FPGLGLGLVISGAVRVHEDMLLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAAKAYELGLATRLPPPSDLV
KYAENCMYTPVYRNYR
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PYRUVIC ACID' PYR 
3 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   HIS n 
1 2   ALA n 
1 3   MET n 
1 4   VAL n 
1 5   SER n 
1 6   ASN n 
1 7   ALA n 
1 8   GLU n 
1 9   THR n 
1 10  GLU n 
1 11  THR n 
1 12  GLU n 
1 13  LYS n 
1 14  GLU n 
1 15  GLN n 
1 16  GLU n 
1 17  GLU n 
1 18  ALA n 
1 19  ALA n 
1 20  ALA n 
1 21  ALA n 
1 22  SER n 
1 23  GLU n 
1 24  GLU n 
1 25  LEU n 
1 26  PRO n 
1 27  VAL n 
1 28  MET n 
1 29  PRO n 
1 30  TRP n 
1 31  ALA n 
1 32  THR n 
1 33  SER n 
1 34  VAL n 
1 35  ALA n 
1 36  SER n 
1 37  GLY n 
1 38  TYR n 
1 39  THR n 
1 40  LEU n 
1 41  LEU n 
1 42  ARG n 
1 43  ASP n 
1 44  PRO n 
1 45  HIS n 
1 46  HIS n 
1 47  ASN n 
1 48  LYS n 
1 49  GLY n 
1 50  LEU n 
1 51  ALA n 
1 52  PHE n 
1 53  THR n 
1 54  GLU n 
1 55  GLU n 
1 56  GLU n 
1 57  ARG n 
1 58  ASP n 
1 59  GLY n 
1 60  HIS n 
1 61  TYR n 
1 62  LEU n 
1 63  ARG n 
1 64  GLY n 
1 65  LEU n 
1 66  LEU n 
1 67  PRO n 
1 68  PRO n 
1 69  ALA n 
1 70  VAL n 
1 71  LEU n 
1 72  SER n 
1 73  GLN n 
1 74  GLU n 
1 75  LEU n 
1 76  GLN n 
1 77  ILE n 
1 78  LYS n 
1 79  LYS n 
1 80  PHE n 
1 81  MET n 
1 82  ASN n 
1 83  THR n 
1 84  LEU n 
1 85  ARG n 
1 86  GLN n 
1 87  TYR n 
1 88  GLN n 
1 89  THR n 
1 90  PRO n 
1 91  LEU n 
1 92  GLN n 
1 93  ARG n 
1 94  TYR n 
1 95  ILE n 
1 96  ALA n 
1 97  MET n 
1 98  MET n 
1 99  ASN n 
1 100 LEU n 
1 101 GLN n 
1 102 GLU n 
1 103 THR n 
1 104 ASP n 
1 105 GLU n 
1 106 ARG n 
1 107 LEU n 
1 108 PHE n 
1 109 TYR n 
1 110 LYS n 
1 111 LEU n 
1 112 LEU n 
1 113 ILE n 
1 114 ASP n 
1 115 ASN n 
1 116 VAL n 
1 117 VAL n 
1 118 GLU n 
1 119 LEU n 
1 120 LEU n 
1 121 PRO n 
1 122 PHE n 
1 123 VAL n 
1 124 TYR n 
1 125 THR n 
1 126 PRO n 
1 127 THR n 
1 128 VAL n 
1 129 GLY n 
1 130 GLU n 
1 131 ALA n 
1 132 CYS n 
1 133 GLN n 
1 134 LYS n 
1 135 TYR n 
1 136 GLY n 
1 137 SER n 
1 138 ILE n 
1 139 PHE n 
1 140 ARG n 
1 141 ARG n 
1 142 PRO n 
1 143 GLN n 
1 144 GLY n 
1 145 LEU n 
1 146 TYR n 
1 147 VAL n 
1 148 SER n 
1 149 LEU n 
1 150 LYS n 
1 151 ASP n 
1 152 LYS n 
1 153 GLY n 
1 154 LYS n 
1 155 VAL n 
1 156 LEU n 
1 157 GLU n 
1 158 VAL n 
1 159 LEU n 
1 160 ARG n 
1 161 ASN n 
1 162 TRP n 
1 163 PRO n 
1 164 HIS n 
1 165 ARG n 
1 166 ASN n 
1 167 ILE n 
1 168 GLN n 
1 169 VAL n 
1 170 ILE n 
1 171 CYS n 
1 172 VAL n 
1 173 THR n 
1 174 ASP n 
1 175 GLY n 
1 176 GLU n 
1 177 ARG n 
1 178 ILE n 
1 179 LEU n 
1 180 GLY n 
1 181 LEU n 
1 182 GLY n 
1 183 ASP n 
1 184 LEU n 
1 185 GLY n 
1 186 CYS n 
1 187 GLN n 
1 188 GLY n 
1 189 MET n 
1 190 GLY n 
1 191 ILE n 
1 192 PRO n 
1 193 VAL n 
1 194 GLY n 
1 195 LYS n 
1 196 LEU n 
1 197 ALA n 
1 198 LEU n 
1 199 TYR n 
1 200 THR n 
1 201 ALA n 
1 202 LEU n 
1 203 GLY n 
1 204 GLY n 
1 205 VAL n 
1 206 ASP n 
1 207 PRO n 
1 208 SER n 
1 209 VAL n 
1 210 CYS n 
1 211 LEU n 
1 212 PRO n 
1 213 ILE n 
1 214 THR n 
1 215 ILE n 
1 216 ASP n 
1 217 VAL n 
1 218 GLY n 
1 219 THR n 
1 220 ASN n 
1 221 ASN n 
1 222 GLU n 
1 223 LYS n 
1 224 LEU n 
1 225 LEU n 
1 226 ASN n 
1 227 ASP n 
1 228 GLU n 
1 229 PHE n 
1 230 TYR n 
1 231 ILE n 
1 232 GLY n 
1 233 LEU n 
1 234 ARG n 
1 235 GLN n 
1 236 LYS n 
1 237 ARG n 
1 238 ALA n 
1 239 THR n 
1 240 GLY n 
1 241 GLU n 
1 242 GLU n 
1 243 TYR n 
1 244 ASP n 
1 245 GLU n 
1 246 LEU n 
1 247 ILE n 
1 248 GLU n 
1 249 GLU n 
1 250 PHE n 
1 251 MET n 
1 252 SER n 
1 253 ALA n 
1 254 VAL n 
1 255 LYS n 
1 256 GLN n 
1 257 PHE n 
1 258 TYR n 
1 259 GLY n 
1 260 GLU n 
1 261 LYS n 
1 262 VAL n 
1 263 LEU n 
1 264 ILE n 
1 265 GLN n 
1 266 PHE n 
1 267 GLU n 
1 268 ASP n 
1 269 PHE n 
1 270 ALA n 
1 271 ASN n 
1 272 HIS n 
1 273 ASN n 
1 274 ALA n 
1 275 PHE n 
1 276 ASP n 
1 277 LEU n 
1 278 LEU n 
1 279 GLU n 
1 280 LYS n 
1 281 TYR n 
1 282 SER n 
1 283 LYS n 
1 284 SER n 
1 285 HIS n 
1 286 LEU n 
1 287 VAL n 
1 288 PHE n 
1 289 ASN n 
1 290 ASP n 
1 291 ASP n 
1 292 ILE n 
1 293 GLN n 
1 294 GLY n 
1 295 THR n 
1 296 ALA n 
1 297 SER n 
1 298 VAL n 
1 299 VAL n 
1 300 LEU n 
1 301 ALA n 
1 302 GLY n 
1 303 LEU n 
1 304 LEU n 
1 305 ALA n 
1 306 ALA n 
1 307 LEU n 
1 308 LYS n 
1 309 MET n 
1 310 VAL n 
1 311 GLY n 
1 312 GLY n 
1 313 THR n 
1 314 LEU n 
1 315 ALA n 
1 316 GLU n 
1 317 GLN n 
1 318 THR n 
1 319 TYR n 
1 320 LEU n 
1 321 PHE n 
1 322 LEU n 
1 323 GLY n 
1 324 ALA n 
1 325 GLY n 
1 326 GLU n 
1 327 ALA n 
1 328 GLY n 
1 329 THR n 
1 330 GLY n 
1 331 ILE n 
1 332 ALA n 
1 333 GLU n 
1 334 LEU n 
1 335 ILE n 
1 336 ALA n 
1 337 LEU n 
1 338 GLU n 
1 339 ILE n 
1 340 SER n 
1 341 LYS n 
1 342 GLN n 
1 343 THR n 
1 344 ASN n 
1 345 ALA n 
1 346 PRO n 
1 347 ILE n 
1 348 GLU n 
1 349 GLU n 
1 350 CYS n 
1 351 ARG n 
1 352 LYS n 
1 353 LYS n 
1 354 VAL n 
1 355 TRP n 
1 356 LEU n 
1 357 VAL n 
1 358 ASP n 
1 359 SER n 
1 360 LYS n 
1 361 GLY n 
1 362 LEU n 
1 363 ILE n 
1 364 VAL n 
1 365 ASP n 
1 366 SER n 
1 367 ARG n 
1 368 LYS n 
1 369 GLY n 
1 370 SER n 
1 371 LEU n 
1 372 GLN n 
1 373 PRO n 
1 374 PHE n 
1 375 LYS n 
1 376 LYS n 
1 377 PRO n 
1 378 TRP n 
1 379 ALA n 
1 380 HIS n 
1 381 GLU n 
1 382 HIS n 
1 383 GLU n 
1 384 PRO n 
1 385 LEU n 
1 386 LYS n 
1 387 THR n 
1 388 LEU n 
1 389 TYR n 
1 390 ASP n 
1 391 ALA n 
1 392 VAL n 
1 393 GLN n 
1 394 SER n 
1 395 ILE n 
1 396 LYS n 
1 397 PRO n 
1 398 THR n 
1 399 VAL n 
1 400 LEU n 
1 401 ILE n 
1 402 GLY n 
1 403 THR n 
1 404 SER n 
1 405 GLY n 
1 406 VAL n 
1 407 GLY n 
1 408 ARG n 
1 409 THR n 
1 410 PHE n 
1 411 THR n 
1 412 LYS n 
1 413 GLU n 
1 414 ILE n 
1 415 ILE n 
1 416 GLU n 
1 417 ALA n 
1 418 MET n 
1 419 SER n 
1 420 SER n 
1 421 PHE n 
1 422 ASN n 
1 423 GLU n 
1 424 ARG n 
1 425 PRO n 
1 426 ILE n 
1 427 ILE n 
1 428 PHE n 
1 429 SER n 
1 430 LEU n 
1 431 SER n 
1 432 ASN n 
1 433 PRO n 
1 434 THR n 
1 435 SER n 
1 436 HIS n 
1 437 SER n 
1 438 GLU n 
1 439 CYS n 
1 440 THR n 
1 441 ALA n 
1 442 GLU n 
1 443 GLN n 
1 444 ALA n 
1 445 TYR n 
1 446 THR n 
1 447 TRP n 
1 448 SER n 
1 449 GLN n 
1 450 GLY n 
1 451 ARG n 
1 452 SER n 
1 453 ILE n 
1 454 PHE n 
1 455 ALA n 
1 456 SER n 
1 457 GLY n 
1 458 SER n 
1 459 PRO n 
1 460 PHE n 
1 461 ALA n 
1 462 PRO n 
1 463 VAL n 
1 464 GLU n 
1 465 TYR n 
1 466 GLU n 
1 467 GLY n 
1 468 LYS n 
1 469 THR n 
1 470 PHE n 
1 471 VAL n 
1 472 PRO n 
1 473 GLY n 
1 474 GLN n 
1 475 SER n 
1 476 ASN n 
1 477 ASN n 
1 478 ALA n 
1 479 TYR n 
1 480 ILE n 
1 481 PHE n 
1 482 PRO n 
1 483 GLY n 
1 484 LEU n 
1 485 GLY n 
1 486 LEU n 
1 487 GLY n 
1 488 LEU n 
1 489 VAL n 
1 490 ILE n 
1 491 SER n 
1 492 GLY n 
1 493 ALA n 
1 494 VAL n 
1 495 ARG n 
1 496 VAL n 
1 497 HIS n 
1 498 GLU n 
1 499 ASP n 
1 500 MET n 
1 501 LEU n 
1 502 LEU n 
1 503 ALA n 
1 504 ALA n 
1 505 SER n 
1 506 LYS n 
1 507 ALA n 
1 508 LEU n 
1 509 ALA n 
1 510 ASP n 
1 511 GLN n 
1 512 ALA n 
1 513 THR n 
1 514 GLN n 
1 515 ASP n 
1 516 ASN n 
1 517 PHE n 
1 518 GLU n 
1 519 LYS n 
1 520 GLY n 
1 521 SER n 
1 522 ILE n 
1 523 PHE n 
1 524 PRO n 
1 525 PRO n 
1 526 PHE n 
1 527 THR n 
1 528 SER n 
1 529 ILE n 
1 530 ARG n 
1 531 LYS n 
1 532 ILE n 
1 533 SER n 
1 534 ALA n 
1 535 HIS n 
1 536 ILE n 
1 537 ALA n 
1 538 ALA n 
1 539 ALA n 
1 540 VAL n 
1 541 ALA n 
1 542 ALA n 
1 543 LYS n 
1 544 ALA n 
1 545 TYR n 
1 546 GLU n 
1 547 LEU n 
1 548 GLY n 
1 549 LEU n 
1 550 ALA n 
1 551 THR n 
1 552 ARG n 
1 553 LEU n 
1 554 PRO n 
1 555 PRO n 
1 556 PRO n 
1 557 SER n 
1 558 ASP n 
1 559 LEU n 
1 560 VAL n 
1 561 LYS n 
1 562 TYR n 
1 563 ALA n 
1 564 GLU n 
1 565 ASN n 
1 566 CYS n 
1 567 MET n 
1 568 TYR n 
1 569 THR n 
1 570 PRO n 
1 571 VAL n 
1 572 TYR n 
1 573 ARG n 
1 574 ASN n 
1 575 TYR n 
1 576 ARG n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   576 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Zea mays' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     4577 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pET28b 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
PYR non-polymer         . 'PYRUVIC ACID'  ? 'C3 H4 O3'       88.062  
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   HIS 1   61  ?   ?   ?   A . n 
A 1 2   ALA 2   62  ?   ?   ?   A . n 
A 1 3   MET 3   63  ?   ?   ?   A . n 
A 1 4   VAL 4   64  ?   ?   ?   A . n 
A 1 5   SER 5   65  ?   ?   ?   A . n 
A 1 6   ASN 6   66  ?   ?   ?   A . n 
A 1 7   ALA 7   67  ?   ?   ?   A . n 
A 1 8   GLU 8   68  ?   ?   ?   A . n 
A 1 9   THR 9   69  ?   ?   ?   A . n 
A 1 10  GLU 10  70  ?   ?   ?   A . n 
A 1 11  THR 11  71  ?   ?   ?   A . n 
A 1 12  GLU 12  72  72  GLU GLU A . n 
A 1 13  LYS 13  73  73  LYS LYS A . n 
A 1 14  GLU 14  74  74  GLU GLU A . n 
A 1 15  GLN 15  75  75  GLN GLN A . n 
A 1 16  GLU 16  76  76  GLU GLU A . n 
A 1 17  GLU 17  77  77  GLU GLU A . n 
A 1 18  ALA 18  78  78  ALA ALA A . n 
A 1 19  ALA 19  79  79  ALA ALA A . n 
A 1 20  ALA 20  80  80  ALA ALA A . n 
A 1 21  ALA 21  81  81  ALA ALA A . n 
A 1 22  SER 22  82  82  SER SER A . n 
A 1 23  GLU 23  83  83  GLU GLU A . n 
A 1 24  GLU 24  84  84  GLU GLU A . n 
A 1 25  LEU 25  85  85  LEU LEU A . n 
A 1 26  PRO 26  86  86  PRO PRO A . n 
A 1 27  VAL 27  87  87  VAL VAL A . n 
A 1 28  MET 28  88  88  MET MET A . n 
A 1 29  PRO 29  89  89  PRO PRO A . n 
A 1 30  TRP 30  90  90  TRP TRP A . n 
A 1 31  ALA 31  91  91  ALA ALA A . n 
A 1 32  THR 32  92  92  THR THR A . n 
A 1 33  SER 33  93  93  SER SER A . n 
A 1 34  VAL 34  94  94  VAL VAL A . n 
A 1 35  ALA 35  95  95  ALA ALA A . n 
A 1 36  SER 36  96  96  SER SER A . n 
A 1 37  GLY 37  97  97  GLY GLY A . n 
A 1 38  TYR 38  98  98  TYR TYR A . n 
A 1 39  THR 39  99  99  THR THR A . n 
A 1 40  LEU 40  100 100 LEU LEU A . n 
A 1 41  LEU 41  101 101 LEU LEU A . n 
A 1 42  ARG 42  102 102 ARG ARG A . n 
A 1 43  ASP 43  103 103 ASP ASP A . n 
A 1 44  PRO 44  104 104 PRO PRO A . n 
A 1 45  HIS 45  105 105 HIS HIS A . n 
A 1 46  HIS 46  106 106 HIS HIS A . n 
A 1 47  ASN 47  107 107 ASN ASN A . n 
A 1 48  LYS 48  108 108 LYS LYS A . n 
A 1 49  GLY 49  109 109 GLY GLY A . n 
A 1 50  LEU 50  110 110 LEU LEU A . n 
A 1 51  ALA 51  111 111 ALA ALA A . n 
A 1 52  PHE 52  112 112 PHE PHE A . n 
A 1 53  THR 53  113 113 THR THR A . n 
A 1 54  GLU 54  114 114 GLU GLU A . n 
A 1 55  GLU 55  115 115 GLU GLU A . n 
A 1 56  GLU 56  116 116 GLU GLU A . n 
A 1 57  ARG 57  117 117 ARG ARG A . n 
A 1 58  ASP 58  118 118 ASP ASP A . n 
A 1 59  GLY 59  119 119 GLY GLY A . n 
A 1 60  HIS 60  120 120 HIS HIS A . n 
A 1 61  TYR 61  121 121 TYR TYR A . n 
A 1 62  LEU 62  122 122 LEU LEU A . n 
A 1 63  ARG 63  123 123 ARG ARG A . n 
A 1 64  GLY 64  124 124 GLY GLY A . n 
A 1 65  LEU 65  125 125 LEU LEU A . n 
A 1 66  LEU 66  126 126 LEU LEU A . n 
A 1 67  PRO 67  127 127 PRO PRO A . n 
A 1 68  PRO 68  128 128 PRO PRO A . n 
A 1 69  ALA 69  129 129 ALA ALA A . n 
A 1 70  VAL 70  130 130 VAL VAL A . n 
A 1 71  LEU 71  131 131 LEU LEU A . n 
A 1 72  SER 72  132 132 SER SER A . n 
A 1 73  GLN 73  133 133 GLN GLN A . n 
A 1 74  GLU 74  134 134 GLU GLU A . n 
A 1 75  LEU 75  135 135 LEU LEU A . n 
A 1 76  GLN 76  136 136 GLN GLN A . n 
A 1 77  ILE 77  137 137 ILE ILE A . n 
A 1 78  LYS 78  138 138 LYS LYS A . n 
A 1 79  LYS 79  139 139 LYS LYS A . n 
A 1 80  PHE 80  140 140 PHE PHE A . n 
A 1 81  MET 81  141 141 MET MET A . n 
A 1 82  ASN 82  142 142 ASN ASN A . n 
A 1 83  THR 83  143 143 THR THR A . n 
A 1 84  LEU 84  144 144 LEU LEU A . n 
A 1 85  ARG 85  145 145 ARG ARG A . n 
A 1 86  GLN 86  146 146 GLN GLN A . n 
A 1 87  TYR 87  147 147 TYR TYR A . n 
A 1 88  GLN 88  148 148 GLN GLN A . n 
A 1 89  THR 89  149 149 THR THR A . n 
A 1 90  PRO 90  150 150 PRO PRO A . n 
A 1 91  LEU 91  151 151 LEU LEU A . n 
A 1 92  GLN 92  152 152 GLN GLN A . n 
A 1 93  ARG 93  153 153 ARG ARG A . n 
A 1 94  TYR 94  154 154 TYR TYR A . n 
A 1 95  ILE 95  155 155 ILE ILE A . n 
A 1 96  ALA 96  156 156 ALA ALA A . n 
A 1 97  MET 97  157 157 MET MET A . n 
A 1 98  MET 98  158 158 MET MET A . n 
A 1 99  ASN 99  159 159 ASN ASN A . n 
A 1 100 LEU 100 160 160 LEU LEU A . n 
A 1 101 GLN 101 161 161 GLN GLN A . n 
A 1 102 GLU 102 162 162 GLU GLU A . n 
A 1 103 THR 103 163 163 THR THR A . n 
A 1 104 ASP 104 164 164 ASP ASP A . n 
A 1 105 GLU 105 165 165 GLU GLU A . n 
A 1 106 ARG 106 166 166 ARG ARG A . n 
A 1 107 LEU 107 167 167 LEU LEU A . n 
A 1 108 PHE 108 168 168 PHE PHE A . n 
A 1 109 TYR 109 169 169 TYR TYR A . n 
A 1 110 LYS 110 170 170 LYS LYS A . n 
A 1 111 LEU 111 171 171 LEU LEU A . n 
A 1 112 LEU 112 172 172 LEU LEU A . n 
A 1 113 ILE 113 173 173 ILE ILE A . n 
A 1 114 ASP 114 174 174 ASP ASP A . n 
A 1 115 ASN 115 175 175 ASN ASN A . n 
A 1 116 VAL 116 176 176 VAL VAL A . n 
A 1 117 VAL 117 177 177 VAL VAL A . n 
A 1 118 GLU 118 178 178 GLU GLU A . n 
A 1 119 LEU 119 179 179 LEU LEU A . n 
A 1 120 LEU 120 180 180 LEU LEU A . n 
A 1 121 PRO 121 181 181 PRO PRO A . n 
A 1 122 PHE 122 182 182 PHE PHE A . n 
A 1 123 VAL 123 183 183 VAL VAL A . n 
A 1 124 TYR 124 184 184 TYR TYR A . n 
A 1 125 THR 125 185 185 THR THR A . n 
A 1 126 PRO 126 186 186 PRO PRO A . n 
A 1 127 THR 127 187 187 THR THR A . n 
A 1 128 VAL 128 188 188 VAL VAL A . n 
A 1 129 GLY 129 189 189 GLY GLY A . n 
A 1 130 GLU 130 190 190 GLU GLU A . n 
A 1 131 ALA 131 191 191 ALA ALA A . n 
A 1 132 CYS 132 192 192 CYS CYS A . n 
A 1 133 GLN 133 193 193 GLN GLN A . n 
A 1 134 LYS 134 194 194 LYS LYS A . n 
A 1 135 TYR 135 195 195 TYR TYR A . n 
A 1 136 GLY 136 196 196 GLY GLY A . n 
A 1 137 SER 137 197 197 SER SER A . n 
A 1 138 ILE 138 198 198 ILE ILE A . n 
A 1 139 PHE 139 199 199 PHE PHE A . n 
A 1 140 ARG 140 200 200 ARG ARG A . n 
A 1 141 ARG 141 201 201 ARG ARG A . n 
A 1 142 PRO 142 202 202 PRO PRO A . n 
A 1 143 GLN 143 203 203 GLN GLN A . n 
A 1 144 GLY 144 204 204 GLY GLY A . n 
A 1 145 LEU 145 205 205 LEU LEU A . n 
A 1 146 TYR 146 206 206 TYR TYR A . n 
A 1 147 VAL 147 207 207 VAL VAL A . n 
A 1 148 SER 148 208 208 SER SER A . n 
A 1 149 LEU 149 209 209 LEU LEU A . n 
A 1 150 LYS 150 210 210 LYS LYS A . n 
A 1 151 ASP 151 211 211 ASP ASP A . n 
A 1 152 LYS 152 212 212 LYS LYS A . n 
A 1 153 GLY 153 213 213 GLY GLY A . n 
A 1 154 LYS 154 214 214 LYS LYS A . n 
A 1 155 VAL 155 215 215 VAL VAL A . n 
A 1 156 LEU 156 216 216 LEU LEU A . n 
A 1 157 GLU 157 217 217 GLU GLU A . n 
A 1 158 VAL 158 218 218 VAL VAL A . n 
A 1 159 LEU 159 219 219 LEU LEU A . n 
A 1 160 ARG 160 220 220 ARG ARG A . n 
A 1 161 ASN 161 221 221 ASN ASN A . n 
A 1 162 TRP 162 222 222 TRP TRP A . n 
A 1 163 PRO 163 223 223 PRO PRO A . n 
A 1 164 HIS 164 224 224 HIS HIS A . n 
A 1 165 ARG 165 225 225 ARG ARG A . n 
A 1 166 ASN 166 226 226 ASN ASN A . n 
A 1 167 ILE 167 227 227 ILE ILE A . n 
A 1 168 GLN 168 228 228 GLN GLN A . n 
A 1 169 VAL 169 229 229 VAL VAL A . n 
A 1 170 ILE 170 230 230 ILE ILE A . n 
A 1 171 CYS 171 231 231 CYS CYS A . n 
A 1 172 VAL 172 232 232 VAL VAL A . n 
A 1 173 THR 173 233 233 THR THR A . n 
A 1 174 ASP 174 234 234 ASP ASP A . n 
A 1 175 GLY 175 235 235 GLY GLY A . n 
A 1 176 GLU 176 236 236 GLU GLU A . n 
A 1 177 ARG 177 237 237 ARG ARG A . n 
A 1 178 ILE 178 238 238 ILE ILE A . n 
A 1 179 LEU 179 239 239 LEU LEU A . n 
A 1 180 GLY 180 240 240 GLY GLY A . n 
A 1 181 LEU 181 241 241 LEU LEU A . n 
A 1 182 GLY 182 242 242 GLY GLY A . n 
A 1 183 ASP 183 243 243 ASP ASP A . n 
A 1 184 LEU 184 244 244 LEU LEU A . n 
A 1 185 GLY 185 245 245 GLY GLY A . n 
A 1 186 CYS 186 246 246 CYS CYS A . n 
A 1 187 GLN 187 247 247 GLN GLN A . n 
A 1 188 GLY 188 248 248 GLY GLY A . n 
A 1 189 MET 189 249 249 MET MET A . n 
A 1 190 GLY 190 250 250 GLY GLY A . n 
A 1 191 ILE 191 251 251 ILE ILE A . n 
A 1 192 PRO 192 252 252 PRO PRO A . n 
A 1 193 VAL 193 253 253 VAL VAL A . n 
A 1 194 GLY 194 254 254 GLY GLY A . n 
A 1 195 LYS 195 255 255 LYS LYS A . n 
A 1 196 LEU 196 256 256 LEU LEU A . n 
A 1 197 ALA 197 257 257 ALA ALA A . n 
A 1 198 LEU 198 258 258 LEU LEU A . n 
A 1 199 TYR 199 259 259 TYR TYR A . n 
A 1 200 THR 200 260 260 THR THR A . n 
A 1 201 ALA 201 261 261 ALA ALA A . n 
A 1 202 LEU 202 262 262 LEU LEU A . n 
A 1 203 GLY 203 263 263 GLY GLY A . n 
A 1 204 GLY 204 264 264 GLY GLY A . n 
A 1 205 VAL 205 265 265 VAL VAL A . n 
A 1 206 ASP 206 266 266 ASP ASP A . n 
A 1 207 PRO 207 267 267 PRO PRO A . n 
A 1 208 SER 208 268 268 SER SER A . n 
A 1 209 VAL 209 269 269 VAL VAL A . n 
A 1 210 CYS 210 270 270 CYS CYS A . n 
A 1 211 LEU 211 271 271 LEU LEU A . n 
A 1 212 PRO 212 272 272 PRO PRO A . n 
A 1 213 ILE 213 273 273 ILE ILE A . n 
A 1 214 THR 214 274 274 THR THR A . n 
A 1 215 ILE 215 275 275 ILE ILE A . n 
A 1 216 ASP 216 276 276 ASP ASP A . n 
A 1 217 VAL 217 277 277 VAL VAL A . n 
A 1 218 GLY 218 278 278 GLY GLY A . n 
A 1 219 THR 219 279 279 THR THR A . n 
A 1 220 ASN 220 280 280 ASN ASN A . n 
A 1 221 ASN 221 281 281 ASN ASN A . n 
A 1 222 GLU 222 282 282 GLU GLU A . n 
A 1 223 LYS 223 283 283 LYS LYS A . n 
A 1 224 LEU 224 284 284 LEU LEU A . n 
A 1 225 LEU 225 285 285 LEU LEU A . n 
A 1 226 ASN 226 286 286 ASN ASN A . n 
A 1 227 ASP 227 287 287 ASP ASP A . n 
A 1 228 GLU 228 288 288 GLU GLU A . n 
A 1 229 PHE 229 289 289 PHE PHE A . n 
A 1 230 TYR 230 290 290 TYR TYR A . n 
A 1 231 ILE 231 291 291 ILE ILE A . n 
A 1 232 GLY 232 292 292 GLY GLY A . n 
A 1 233 LEU 233 293 293 LEU LEU A . n 
A 1 234 ARG 234 294 294 ARG ARG A . n 
A 1 235 GLN 235 295 295 GLN GLN A . n 
A 1 236 LYS 236 296 296 LYS LYS A . n 
A 1 237 ARG 237 297 297 ARG ARG A . n 
A 1 238 ALA 238 298 298 ALA ALA A . n 
A 1 239 THR 239 299 299 THR THR A . n 
A 1 240 GLY 240 300 300 GLY GLY A . n 
A 1 241 GLU 241 301 301 GLU GLU A . n 
A 1 242 GLU 242 302 302 GLU GLU A . n 
A 1 243 TYR 243 303 303 TYR TYR A . n 
A 1 244 ASP 244 304 304 ASP ASP A . n 
A 1 245 GLU 245 305 305 GLU GLU A . n 
A 1 246 LEU 246 306 306 LEU LEU A . n 
A 1 247 ILE 247 307 307 ILE ILE A . n 
A 1 248 GLU 248 308 308 GLU GLU A . n 
A 1 249 GLU 249 309 309 GLU GLU A . n 
A 1 250 PHE 250 310 310 PHE PHE A . n 
A 1 251 MET 251 311 311 MET MET A . n 
A 1 252 SER 252 312 312 SER SER A . n 
A 1 253 ALA 253 313 313 ALA ALA A . n 
A 1 254 VAL 254 314 314 VAL VAL A . n 
A 1 255 LYS 255 315 315 LYS LYS A . n 
A 1 256 GLN 256 316 316 GLN GLN A . n 
A 1 257 PHE 257 317 317 PHE PHE A . n 
A 1 258 TYR 258 318 318 TYR TYR A . n 
A 1 259 GLY 259 319 319 GLY GLY A . n 
A 1 260 GLU 260 320 320 GLU GLU A . n 
A 1 261 LYS 261 321 321 LYS LYS A . n 
A 1 262 VAL 262 322 322 VAL VAL A . n 
A 1 263 LEU 263 323 323 LEU LEU A . n 
A 1 264 ILE 264 324 324 ILE ILE A . n 
A 1 265 GLN 265 325 325 GLN GLN A . n 
A 1 266 PHE 266 326 326 PHE PHE A . n 
A 1 267 GLU 267 327 327 GLU GLU A . n 
A 1 268 ASP 268 328 328 ASP ASP A . n 
A 1 269 PHE 269 329 329 PHE PHE A . n 
A 1 270 ALA 270 330 330 ALA ALA A . n 
A 1 271 ASN 271 331 331 ASN ASN A . n 
A 1 272 HIS 272 332 332 HIS HIS A . n 
A 1 273 ASN 273 333 333 ASN ASN A . n 
A 1 274 ALA 274 334 334 ALA ALA A . n 
A 1 275 PHE 275 335 335 PHE PHE A . n 
A 1 276 ASP 276 336 336 ASP ASP A . n 
A 1 277 LEU 277 337 337 LEU LEU A . n 
A 1 278 LEU 278 338 338 LEU LEU A . n 
A 1 279 GLU 279 339 339 GLU GLU A . n 
A 1 280 LYS 280 340 340 LYS LYS A . n 
A 1 281 TYR 281 341 341 TYR TYR A . n 
A 1 282 SER 282 342 342 SER SER A . n 
A 1 283 LYS 283 343 343 LYS LYS A . n 
A 1 284 SER 284 344 344 SER SER A . n 
A 1 285 HIS 285 345 345 HIS HIS A . n 
A 1 286 LEU 286 346 346 LEU LEU A . n 
A 1 287 VAL 287 347 347 VAL VAL A . n 
A 1 288 PHE 288 348 348 PHE PHE A . n 
A 1 289 ASN 289 349 349 ASN ASN A . n 
A 1 290 ASP 290 350 350 ASP ASP A . n 
A 1 291 ASP 291 351 351 ASP ASP A . n 
A 1 292 ILE 292 352 352 ILE ILE A . n 
A 1 293 GLN 293 353 353 GLN GLN A . n 
A 1 294 GLY 294 354 354 GLY GLY A . n 
A 1 295 THR 295 355 355 THR THR A . n 
A 1 296 ALA 296 356 356 ALA ALA A . n 
A 1 297 SER 297 357 357 SER SER A . n 
A 1 298 VAL 298 358 358 VAL VAL A . n 
A 1 299 VAL 299 359 359 VAL VAL A . n 
A 1 300 LEU 300 360 360 LEU LEU A . n 
A 1 301 ALA 301 361 361 ALA ALA A . n 
A 1 302 GLY 302 362 362 GLY GLY A . n 
A 1 303 LEU 303 363 363 LEU LEU A . n 
A 1 304 LEU 304 364 364 LEU LEU A . n 
A 1 305 ALA 305 365 365 ALA ALA A . n 
A 1 306 ALA 306 366 366 ALA ALA A . n 
A 1 307 LEU 307 367 367 LEU LEU A . n 
A 1 308 LYS 308 368 368 LYS LYS A . n 
A 1 309 MET 309 369 369 MET MET A . n 
A 1 310 VAL 310 370 370 VAL VAL A . n 
A 1 311 GLY 311 371 371 GLY GLY A . n 
A 1 312 GLY 312 372 372 GLY GLY A . n 
A 1 313 THR 313 373 373 THR THR A . n 
A 1 314 LEU 314 374 374 LEU LEU A . n 
A 1 315 ALA 315 375 375 ALA ALA A . n 
A 1 316 GLU 316 376 376 GLU GLU A . n 
A 1 317 GLN 317 377 377 GLN GLN A . n 
A 1 318 THR 318 378 378 THR THR A . n 
A 1 319 TYR 319 379 379 TYR TYR A . n 
A 1 320 LEU 320 380 380 LEU LEU A . n 
A 1 321 PHE 321 381 381 PHE PHE A . n 
A 1 322 LEU 322 382 382 LEU LEU A . n 
A 1 323 GLY 323 383 383 GLY GLY A . n 
A 1 324 ALA 324 384 384 ALA ALA A . n 
A 1 325 GLY 325 385 385 GLY GLY A . n 
A 1 326 GLU 326 386 386 GLU GLU A . n 
A 1 327 ALA 327 387 387 ALA ALA A . n 
A 1 328 GLY 328 388 388 GLY GLY A . n 
A 1 329 THR 329 389 389 THR THR A . n 
A 1 330 GLY 330 390 390 GLY GLY A . n 
A 1 331 ILE 331 391 391 ILE ILE A . n 
A 1 332 ALA 332 392 392 ALA ALA A . n 
A 1 333 GLU 333 393 393 GLU GLU A . n 
A 1 334 LEU 334 394 394 LEU LEU A . n 
A 1 335 ILE 335 395 395 ILE ILE A . n 
A 1 336 ALA 336 396 396 ALA ALA A . n 
A 1 337 LEU 337 397 397 LEU LEU A . n 
A 1 338 GLU 338 398 398 GLU GLU A . n 
A 1 339 ILE 339 399 399 ILE ILE A . n 
A 1 340 SER 340 400 400 SER SER A . n 
A 1 341 LYS 341 401 401 LYS LYS A . n 
A 1 342 GLN 342 402 402 GLN GLN A . n 
A 1 343 THR 343 403 403 THR THR A . n 
A 1 344 ASN 344 404 404 ASN ASN A . n 
A 1 345 ALA 345 405 405 ALA ALA A . n 
A 1 346 PRO 346 406 406 PRO PRO A . n 
A 1 347 ILE 347 407 407 ILE ILE A . n 
A 1 348 GLU 348 408 408 GLU GLU A . n 
A 1 349 GLU 349 409 409 GLU GLU A . n 
A 1 350 CYS 350 410 410 CYS CYS A . n 
A 1 351 ARG 351 411 411 ARG ARG A . n 
A 1 352 LYS 352 412 412 LYS LYS A . n 
A 1 353 LYS 353 413 413 LYS LYS A . n 
A 1 354 VAL 354 414 414 VAL VAL A . n 
A 1 355 TRP 355 415 415 TRP TRP A . n 
A 1 356 LEU 356 416 416 LEU LEU A . n 
A 1 357 VAL 357 417 417 VAL VAL A . n 
A 1 358 ASP 358 418 418 ASP ASP A . n 
A 1 359 SER 359 419 419 SER SER A . n 
A 1 360 LYS 360 420 420 LYS LYS A . n 
A 1 361 GLY 361 421 421 GLY GLY A . n 
A 1 362 LEU 362 422 422 LEU LEU A . n 
A 1 363 ILE 363 423 423 ILE ILE A . n 
A 1 364 VAL 364 424 424 VAL VAL A . n 
A 1 365 ASP 365 425 425 ASP ASP A . n 
A 1 366 SER 366 426 426 SER SER A . n 
A 1 367 ARG 367 427 427 ARG ARG A . n 
A 1 368 LYS 368 428 428 LYS LYS A . n 
A 1 369 GLY 369 429 429 GLY GLY A . n 
A 1 370 SER 370 430 430 SER SER A . n 
A 1 371 LEU 371 431 431 LEU LEU A . n 
A 1 372 GLN 372 432 432 GLN GLN A . n 
A 1 373 PRO 373 433 433 PRO PRO A . n 
A 1 374 PHE 374 434 434 PHE PHE A . n 
A 1 375 LYS 375 435 435 LYS LYS A . n 
A 1 376 LYS 376 436 436 LYS LYS A . n 
A 1 377 PRO 377 437 437 PRO PRO A . n 
A 1 378 TRP 378 438 438 TRP TRP A . n 
A 1 379 ALA 379 439 439 ALA ALA A . n 
A 1 380 HIS 380 440 440 HIS HIS A . n 
A 1 381 GLU 381 441 441 GLU GLU A . n 
A 1 382 HIS 382 442 442 HIS HIS A . n 
A 1 383 GLU 383 443 443 GLU GLU A . n 
A 1 384 PRO 384 444 444 PRO PRO A . n 
A 1 385 LEU 385 445 445 LEU LEU A . n 
A 1 386 LYS 386 446 446 LYS LYS A . n 
A 1 387 THR 387 447 447 THR THR A . n 
A 1 388 LEU 388 448 448 LEU LEU A . n 
A 1 389 TYR 389 449 449 TYR TYR A . n 
A 1 390 ASP 390 450 450 ASP ASP A . n 
A 1 391 ALA 391 451 451 ALA ALA A . n 
A 1 392 VAL 392 452 452 VAL VAL A . n 
A 1 393 GLN 393 453 453 GLN GLN A . n 
A 1 394 SER 394 454 454 SER SER A . n 
A 1 395 ILE 395 455 455 ILE ILE A . n 
A 1 396 LYS 396 456 456 LYS LYS A . n 
A 1 397 PRO 397 457 457 PRO PRO A . n 
A 1 398 THR 398 458 458 THR THR A . n 
A 1 399 VAL 399 459 459 VAL VAL A . n 
A 1 400 LEU 400 460 460 LEU LEU A . n 
A 1 401 ILE 401 461 461 ILE ILE A . n 
A 1 402 GLY 402 462 462 GLY GLY A . n 
A 1 403 THR 403 463 463 THR THR A . n 
A 1 404 SER 404 464 464 SER SER A . n 
A 1 405 GLY 405 465 465 GLY GLY A . n 
A 1 406 VAL 406 466 466 VAL VAL A . n 
A 1 407 GLY 407 467 467 GLY GLY A . n 
A 1 408 ARG 408 468 468 ARG ARG A . n 
A 1 409 THR 409 469 469 THR THR A . n 
A 1 410 PHE 410 470 470 PHE PHE A . n 
A 1 411 THR 411 471 471 THR THR A . n 
A 1 412 LYS 412 472 472 LYS LYS A . n 
A 1 413 GLU 413 473 473 GLU GLU A . n 
A 1 414 ILE 414 474 474 ILE ILE A . n 
A 1 415 ILE 415 475 475 ILE ILE A . n 
A 1 416 GLU 416 476 476 GLU GLU A . n 
A 1 417 ALA 417 477 477 ALA ALA A . n 
A 1 418 MET 418 478 478 MET MET A . n 
A 1 419 SER 419 479 479 SER SER A . n 
A 1 420 SER 420 480 480 SER SER A . n 
A 1 421 PHE 421 481 481 PHE PHE A . n 
A 1 422 ASN 422 482 482 ASN ASN A . n 
A 1 423 GLU 423 483 483 GLU GLU A . n 
A 1 424 ARG 424 484 484 ARG ARG A . n 
A 1 425 PRO 425 485 485 PRO PRO A . n 
A 1 426 ILE 426 486 486 ILE ILE A . n 
A 1 427 ILE 427 487 487 ILE ILE A . n 
A 1 428 PHE 428 488 488 PHE PHE A . n 
A 1 429 SER 429 489 489 SER SER A . n 
A 1 430 LEU 430 490 490 LEU LEU A . n 
A 1 431 SER 431 491 491 SER SER A . n 
A 1 432 ASN 432 492 492 ASN ASN A . n 
A 1 433 PRO 433 493 493 PRO PRO A . n 
A 1 434 THR 434 494 494 THR THR A . n 
A 1 435 SER 435 495 495 SER SER A . n 
A 1 436 HIS 436 496 496 HIS HIS A . n 
A 1 437 SER 437 497 497 SER SER A . n 
A 1 438 GLU 438 498 498 GLU GLU A . n 
A 1 439 CYS 439 499 499 CYS CYS A . n 
A 1 440 THR 440 500 500 THR THR A . n 
A 1 441 ALA 441 501 501 ALA ALA A . n 
A 1 442 GLU 442 502 502 GLU GLU A . n 
A 1 443 GLN 443 503 503 GLN GLN A . n 
A 1 444 ALA 444 504 504 ALA ALA A . n 
A 1 445 TYR 445 505 505 TYR TYR A . n 
A 1 446 THR 446 506 506 THR THR A . n 
A 1 447 TRP 447 507 507 TRP TRP A . n 
A 1 448 SER 448 508 508 SER SER A . n 
A 1 449 GLN 449 509 509 GLN GLN A . n 
A 1 450 GLY 450 510 510 GLY GLY A . n 
A 1 451 ARG 451 511 511 ARG ARG A . n 
A 1 452 SER 452 512 512 SER SER A . n 
A 1 453 ILE 453 513 513 ILE ILE A . n 
A 1 454 PHE 454 514 514 PHE PHE A . n 
A 1 455 ALA 455 515 515 ALA ALA A . n 
A 1 456 SER 456 516 516 SER SER A . n 
A 1 457 GLY 457 517 517 GLY GLY A . n 
A 1 458 SER 458 518 518 SER SER A . n 
A 1 459 PRO 459 519 519 PRO PRO A . n 
A 1 460 PHE 460 520 520 PHE PHE A . n 
A 1 461 ALA 461 521 521 ALA ALA A . n 
A 1 462 PRO 462 522 522 PRO PRO A . n 
A 1 463 VAL 463 523 523 VAL VAL A . n 
A 1 464 GLU 464 524 524 GLU GLU A . n 
A 1 465 TYR 465 525 525 TYR TYR A . n 
A 1 466 GLU 466 526 526 GLU GLU A . n 
A 1 467 GLY 467 527 527 GLY GLY A . n 
A 1 468 LYS 468 528 528 LYS LYS A . n 
A 1 469 THR 469 529 529 THR THR A . n 
A 1 470 PHE 470 530 530 PHE PHE A . n 
A 1 471 VAL 471 531 531 VAL VAL A . n 
A 1 472 PRO 472 532 532 PRO PRO A . n 
A 1 473 GLY 473 533 533 GLY GLY A . n 
A 1 474 GLN 474 534 534 GLN GLN A . n 
A 1 475 SER 475 535 535 SER SER A . n 
A 1 476 ASN 476 536 536 ASN ASN A . n 
A 1 477 ASN 477 537 537 ASN ASN A . n 
A 1 478 ALA 478 538 538 ALA ALA A . n 
A 1 479 TYR 479 539 539 TYR TYR A . n 
A 1 480 ILE 480 540 540 ILE ILE A . n 
A 1 481 PHE 481 541 541 PHE PHE A . n 
A 1 482 PRO 482 542 542 PRO PRO A . n 
A 1 483 GLY 483 543 543 GLY GLY A . n 
A 1 484 LEU 484 544 544 LEU LEU A . n 
A 1 485 GLY 485 545 545 GLY GLY A . n 
A 1 486 LEU 486 546 546 LEU LEU A . n 
A 1 487 GLY 487 547 547 GLY GLY A . n 
A 1 488 LEU 488 548 548 LEU LEU A . n 
A 1 489 VAL 489 549 549 VAL VAL A . n 
A 1 490 ILE 490 550 550 ILE ILE A . n 
A 1 491 SER 491 551 551 SER SER A . n 
A 1 492 GLY 492 552 552 GLY GLY A . n 
A 1 493 ALA 493 553 553 ALA ALA A . n 
A 1 494 VAL 494 554 554 VAL VAL A . n 
A 1 495 ARG 495 555 555 ARG ARG A . n 
A 1 496 VAL 496 556 556 VAL VAL A . n 
A 1 497 HIS 497 557 557 HIS HIS A . n 
A 1 498 GLU 498 558 558 GLU GLU A . n 
A 1 499 ASP 499 559 559 ASP ASP A . n 
A 1 500 MET 500 560 560 MET MET A . n 
A 1 501 LEU 501 561 561 LEU LEU A . n 
A 1 502 LEU 502 562 562 LEU LEU A . n 
A 1 503 ALA 503 563 563 ALA ALA A . n 
A 1 504 ALA 504 564 564 ALA ALA A . n 
A 1 505 SER 505 565 565 SER SER A . n 
A 1 506 LYS 506 566 566 LYS LYS A . n 
A 1 507 ALA 507 567 567 ALA ALA A . n 
A 1 508 LEU 508 568 568 LEU LEU A . n 
A 1 509 ALA 509 569 569 ALA ALA A . n 
A 1 510 ASP 510 570 570 ASP ASP A . n 
A 1 511 GLN 511 571 571 GLN GLN A . n 
A 1 512 ALA 512 572 572 ALA ALA A . n 
A 1 513 THR 513 573 573 THR THR A . n 
A 1 514 GLN 514 574 574 GLN GLN A . n 
A 1 515 ASP 515 575 575 ASP ASP A . n 
A 1 516 ASN 516 576 576 ASN ASN A . n 
A 1 517 PHE 517 577 577 PHE PHE A . n 
A 1 518 GLU 518 578 578 GLU GLU A . n 
A 1 519 LYS 519 579 579 LYS LYS A . n 
A 1 520 GLY 520 580 580 GLY GLY A . n 
A 1 521 SER 521 581 581 SER SER A . n 
A 1 522 ILE 522 582 582 ILE ILE A . n 
A 1 523 PHE 523 583 583 PHE PHE A . n 
A 1 524 PRO 524 584 584 PRO PRO A . n 
A 1 525 PRO 525 585 585 PRO PRO A . n 
A 1 526 PHE 526 586 586 PHE PHE A . n 
A 1 527 THR 527 587 587 THR THR A . n 
A 1 528 SER 528 588 588 SER SER A . n 
A 1 529 ILE 529 589 589 ILE ILE A . n 
A 1 530 ARG 530 590 590 ARG ARG A . n 
A 1 531 LYS 531 591 591 LYS LYS A . n 
A 1 532 ILE 532 592 592 ILE ILE A . n 
A 1 533 SER 533 593 593 SER SER A . n 
A 1 534 ALA 534 594 594 ALA ALA A . n 
A 1 535 HIS 535 595 595 HIS HIS A . n 
A 1 536 ILE 536 596 596 ILE ILE A . n 
A 1 537 ALA 537 597 597 ALA ALA A . n 
A 1 538 ALA 538 598 598 ALA ALA A . n 
A 1 539 ALA 539 599 599 ALA ALA A . n 
A 1 540 VAL 540 600 600 VAL VAL A . n 
A 1 541 ALA 541 601 601 ALA ALA A . n 
A 1 542 ALA 542 602 602 ALA ALA A . n 
A 1 543 LYS 543 603 603 LYS LYS A . n 
A 1 544 ALA 544 604 604 ALA ALA A . n 
A 1 545 TYR 545 605 605 TYR TYR A . n 
A 1 546 GLU 546 606 606 GLU GLU A . n 
A 1 547 LEU 547 607 607 LEU LEU A . n 
A 1 548 GLY 548 608 608 GLY GLY A . n 
A 1 549 LEU 549 609 609 LEU LEU A . n 
A 1 550 ALA 550 610 610 ALA ALA A . n 
A 1 551 THR 551 611 611 THR THR A . n 
A 1 552 ARG 552 612 612 ARG ARG A . n 
A 1 553 LEU 553 613 613 LEU LEU A . n 
A 1 554 PRO 554 614 614 PRO PRO A . n 
A 1 555 PRO 555 615 615 PRO PRO A . n 
A 1 556 PRO 556 616 616 PRO PRO A . n 
A 1 557 SER 557 617 617 SER SER A . n 
A 1 558 ASP 558 618 618 ASP ASP A . n 
A 1 559 LEU 559 619 619 LEU LEU A . n 
A 1 560 VAL 560 620 620 VAL VAL A . n 
A 1 561 LYS 561 621 621 LYS LYS A . n 
A 1 562 TYR 562 622 622 TYR TYR A . n 
A 1 563 ALA 563 623 623 ALA ALA A . n 
A 1 564 GLU 564 624 624 GLU GLU A . n 
A 1 565 ASN 565 625 625 ASN ASN A . n 
A 1 566 CYS 566 626 626 CYS CYS A . n 
A 1 567 MET 567 627 627 MET MET A . n 
A 1 568 TYR 568 628 628 TYR TYR A . n 
A 1 569 THR 569 629 629 THR THR A . n 
A 1 570 PRO 570 630 630 PRO PRO A . n 
A 1 571 VAL 571 631 631 VAL VAL A . n 
A 1 572 TYR 572 632 632 TYR TYR A . n 
A 1 573 ARG 573 633 633 ARG ARG A . n 
A 1 574 ASN 574 634 634 ASN ASN A . n 
A 1 575 TYR 575 635 635 TYR TYR A . n 
A 1 576 ARG 576 636 636 ARG ARG A . n 
B 1 1   HIS 1   61  ?   ?   ?   B . n 
B 1 2   ALA 2   62  ?   ?   ?   B . n 
B 1 3   MET 3   63  ?   ?   ?   B . n 
B 1 4   VAL 4   64  ?   ?   ?   B . n 
B 1 5   SER 5   65  ?   ?   ?   B . n 
B 1 6   ASN 6   66  ?   ?   ?   B . n 
B 1 7   ALA 7   67  ?   ?   ?   B . n 
B 1 8   GLU 8   68  ?   ?   ?   B . n 
B 1 9   THR 9   69  ?   ?   ?   B . n 
B 1 10  GLU 10  70  ?   ?   ?   B . n 
B 1 11  THR 11  71  ?   ?   ?   B . n 
B 1 12  GLU 12  72  ?   ?   ?   B . n 
B 1 13  LYS 13  73  ?   ?   ?   B . n 
B 1 14  GLU 14  74  ?   ?   ?   B . n 
B 1 15  GLN 15  75  ?   ?   ?   B . n 
B 1 16  GLU 16  76  ?   ?   ?   B . n 
B 1 17  GLU 17  77  ?   ?   ?   B . n 
B 1 18  ALA 18  78  ?   ?   ?   B . n 
B 1 19  ALA 19  79  ?   ?   ?   B . n 
B 1 20  ALA 20  80  ?   ?   ?   B . n 
B 1 21  ALA 21  81  ?   ?   ?   B . n 
B 1 22  SER 22  82  ?   ?   ?   B . n 
B 1 23  GLU 23  83  ?   ?   ?   B . n 
B 1 24  GLU 24  84  84  GLU GLU B . n 
B 1 25  LEU 25  85  85  LEU LEU B . n 
B 1 26  PRO 26  86  86  PRO PRO B . n 
B 1 27  VAL 27  87  87  VAL VAL B . n 
B 1 28  MET 28  88  88  MET MET B . n 
B 1 29  PRO 29  89  89  PRO PRO B . n 
B 1 30  TRP 30  90  90  TRP TRP B . n 
B 1 31  ALA 31  91  91  ALA ALA B . n 
B 1 32  THR 32  92  92  THR THR B . n 
B 1 33  SER 33  93  93  SER SER B . n 
B 1 34  VAL 34  94  94  VAL VAL B . n 
B 1 35  ALA 35  95  95  ALA ALA B . n 
B 1 36  SER 36  96  96  SER SER B . n 
B 1 37  GLY 37  97  97  GLY GLY B . n 
B 1 38  TYR 38  98  98  TYR TYR B . n 
B 1 39  THR 39  99  99  THR THR B . n 
B 1 40  LEU 40  100 100 LEU LEU B . n 
B 1 41  LEU 41  101 101 LEU LEU B . n 
B 1 42  ARG 42  102 102 ARG ARG B . n 
B 1 43  ASP 43  103 103 ASP ASP B . n 
B 1 44  PRO 44  104 104 PRO PRO B . n 
B 1 45  HIS 45  105 105 HIS HIS B . n 
B 1 46  HIS 46  106 106 HIS HIS B . n 
B 1 47  ASN 47  107 107 ASN ASN B . n 
B 1 48  LYS 48  108 108 LYS LYS B . n 
B 1 49  GLY 49  109 109 GLY GLY B . n 
B 1 50  LEU 50  110 110 LEU LEU B . n 
B 1 51  ALA 51  111 111 ALA ALA B . n 
B 1 52  PHE 52  112 112 PHE PHE B . n 
B 1 53  THR 53  113 113 THR THR B . n 
B 1 54  GLU 54  114 114 GLU GLU B . n 
B 1 55  GLU 55  115 115 GLU GLU B . n 
B 1 56  GLU 56  116 116 GLU GLU B . n 
B 1 57  ARG 57  117 117 ARG ARG B . n 
B 1 58  ASP 58  118 118 ASP ASP B . n 
B 1 59  GLY 59  119 119 GLY GLY B . n 
B 1 60  HIS 60  120 120 HIS HIS B . n 
B 1 61  TYR 61  121 121 TYR TYR B . n 
B 1 62  LEU 62  122 122 LEU LEU B . n 
B 1 63  ARG 63  123 123 ARG ARG B . n 
B 1 64  GLY 64  124 124 GLY GLY B . n 
B 1 65  LEU 65  125 125 LEU LEU B . n 
B 1 66  LEU 66  126 126 LEU LEU B . n 
B 1 67  PRO 67  127 127 PRO PRO B . n 
B 1 68  PRO 68  128 128 PRO PRO B . n 
B 1 69  ALA 69  129 129 ALA ALA B . n 
B 1 70  VAL 70  130 130 VAL VAL B . n 
B 1 71  LEU 71  131 131 LEU LEU B . n 
B 1 72  SER 72  132 132 SER SER B . n 
B 1 73  GLN 73  133 133 GLN GLN B . n 
B 1 74  GLU 74  134 134 GLU GLU B . n 
B 1 75  LEU 75  135 135 LEU LEU B . n 
B 1 76  GLN 76  136 136 GLN GLN B . n 
B 1 77  ILE 77  137 137 ILE ILE B . n 
B 1 78  LYS 78  138 138 LYS LYS B . n 
B 1 79  LYS 79  139 139 LYS LYS B . n 
B 1 80  PHE 80  140 140 PHE PHE B . n 
B 1 81  MET 81  141 141 MET MET B . n 
B 1 82  ASN 82  142 142 ASN ASN B . n 
B 1 83  THR 83  143 143 THR THR B . n 
B 1 84  LEU 84  144 144 LEU LEU B . n 
B 1 85  ARG 85  145 145 ARG ARG B . n 
B 1 86  GLN 86  146 146 GLN GLN B . n 
B 1 87  TYR 87  147 147 TYR TYR B . n 
B 1 88  GLN 88  148 148 GLN GLN B . n 
B 1 89  THR 89  149 149 THR THR B . n 
B 1 90  PRO 90  150 150 PRO PRO B . n 
B 1 91  LEU 91  151 151 LEU LEU B . n 
B 1 92  GLN 92  152 152 GLN GLN B . n 
B 1 93  ARG 93  153 153 ARG ARG B . n 
B 1 94  TYR 94  154 154 TYR TYR B . n 
B 1 95  ILE 95  155 155 ILE ILE B . n 
B 1 96  ALA 96  156 156 ALA ALA B . n 
B 1 97  MET 97  157 157 MET MET B . n 
B 1 98  MET 98  158 158 MET MET B . n 
B 1 99  ASN 99  159 159 ASN ASN B . n 
B 1 100 LEU 100 160 160 LEU LEU B . n 
B 1 101 GLN 101 161 161 GLN GLN B . n 
B 1 102 GLU 102 162 162 GLU GLU B . n 
B 1 103 THR 103 163 163 THR THR B . n 
B 1 104 ASP 104 164 164 ASP ASP B . n 
B 1 105 GLU 105 165 165 GLU GLU B . n 
B 1 106 ARG 106 166 166 ARG ARG B . n 
B 1 107 LEU 107 167 167 LEU LEU B . n 
B 1 108 PHE 108 168 168 PHE PHE B . n 
B 1 109 TYR 109 169 169 TYR TYR B . n 
B 1 110 LYS 110 170 170 LYS LYS B . n 
B 1 111 LEU 111 171 171 LEU LEU B . n 
B 1 112 LEU 112 172 172 LEU LEU B . n 
B 1 113 ILE 113 173 173 ILE ILE B . n 
B 1 114 ASP 114 174 174 ASP ASP B . n 
B 1 115 ASN 115 175 175 ASN ASN B . n 
B 1 116 VAL 116 176 176 VAL VAL B . n 
B 1 117 VAL 117 177 177 VAL VAL B . n 
B 1 118 GLU 118 178 178 GLU GLU B . n 
B 1 119 LEU 119 179 179 LEU LEU B . n 
B 1 120 LEU 120 180 180 LEU LEU B . n 
B 1 121 PRO 121 181 181 PRO PRO B . n 
B 1 122 PHE 122 182 182 PHE PHE B . n 
B 1 123 VAL 123 183 183 VAL VAL B . n 
B 1 124 TYR 124 184 184 TYR TYR B . n 
B 1 125 THR 125 185 185 THR THR B . n 
B 1 126 PRO 126 186 186 PRO PRO B . n 
B 1 127 THR 127 187 187 THR THR B . n 
B 1 128 VAL 128 188 188 VAL VAL B . n 
B 1 129 GLY 129 189 189 GLY GLY B . n 
B 1 130 GLU 130 190 190 GLU GLU B . n 
B 1 131 ALA 131 191 191 ALA ALA B . n 
B 1 132 CYS 132 192 192 CYS CYS B . n 
B 1 133 GLN 133 193 193 GLN GLN B . n 
B 1 134 LYS 134 194 194 LYS LYS B . n 
B 1 135 TYR 135 195 195 TYR TYR B . n 
B 1 136 GLY 136 196 196 GLY GLY B . n 
B 1 137 SER 137 197 197 SER SER B . n 
B 1 138 ILE 138 198 198 ILE ILE B . n 
B 1 139 PHE 139 199 199 PHE PHE B . n 
B 1 140 ARG 140 200 200 ARG ARG B . n 
B 1 141 ARG 141 201 201 ARG ARG B . n 
B 1 142 PRO 142 202 202 PRO PRO B . n 
B 1 143 GLN 143 203 203 GLN GLN B . n 
B 1 144 GLY 144 204 204 GLY GLY B . n 
B 1 145 LEU 145 205 205 LEU LEU B . n 
B 1 146 TYR 146 206 206 TYR TYR B . n 
B 1 147 VAL 147 207 207 VAL VAL B . n 
B 1 148 SER 148 208 208 SER SER B . n 
B 1 149 LEU 149 209 209 LEU LEU B . n 
B 1 150 LYS 150 210 210 LYS LYS B . n 
B 1 151 ASP 151 211 211 ASP ASP B . n 
B 1 152 LYS 152 212 212 LYS LYS B . n 
B 1 153 GLY 153 213 213 GLY GLY B . n 
B 1 154 LYS 154 214 214 LYS LYS B . n 
B 1 155 VAL 155 215 215 VAL VAL B . n 
B 1 156 LEU 156 216 216 LEU LEU B . n 
B 1 157 GLU 157 217 217 GLU GLU B . n 
B 1 158 VAL 158 218 218 VAL VAL B . n 
B 1 159 LEU 159 219 219 LEU LEU B . n 
B 1 160 ARG 160 220 220 ARG ARG B . n 
B 1 161 ASN 161 221 221 ASN ASN B . n 
B 1 162 TRP 162 222 222 TRP TRP B . n 
B 1 163 PRO 163 223 223 PRO PRO B . n 
B 1 164 HIS 164 224 224 HIS HIS B . n 
B 1 165 ARG 165 225 225 ARG ARG B . n 
B 1 166 ASN 166 226 226 ASN ASN B . n 
B 1 167 ILE 167 227 227 ILE ILE B . n 
B 1 168 GLN 168 228 228 GLN GLN B . n 
B 1 169 VAL 169 229 229 VAL VAL B . n 
B 1 170 ILE 170 230 230 ILE ILE B . n 
B 1 171 CYS 171 231 231 CYS CYS B . n 
B 1 172 VAL 172 232 232 VAL VAL B . n 
B 1 173 THR 173 233 233 THR THR B . n 
B 1 174 ASP 174 234 234 ASP ASP B . n 
B 1 175 GLY 175 235 235 GLY GLY B . n 
B 1 176 GLU 176 236 236 GLU GLU B . n 
B 1 177 ARG 177 237 237 ARG ARG B . n 
B 1 178 ILE 178 238 238 ILE ILE B . n 
B 1 179 LEU 179 239 239 LEU LEU B . n 
B 1 180 GLY 180 240 240 GLY GLY B . n 
B 1 181 LEU 181 241 241 LEU LEU B . n 
B 1 182 GLY 182 242 242 GLY GLY B . n 
B 1 183 ASP 183 243 243 ASP ASP B . n 
B 1 184 LEU 184 244 244 LEU LEU B . n 
B 1 185 GLY 185 245 245 GLY GLY B . n 
B 1 186 CYS 186 246 246 CYS CYS B . n 
B 1 187 GLN 187 247 247 GLN GLN B . n 
B 1 188 GLY 188 248 248 GLY GLY B . n 
B 1 189 MET 189 249 249 MET MET B . n 
B 1 190 GLY 190 250 250 GLY GLY B . n 
B 1 191 ILE 191 251 251 ILE ILE B . n 
B 1 192 PRO 192 252 252 PRO PRO B . n 
B 1 193 VAL 193 253 253 VAL VAL B . n 
B 1 194 GLY 194 254 254 GLY GLY B . n 
B 1 195 LYS 195 255 255 LYS LYS B . n 
B 1 196 LEU 196 256 256 LEU LEU B . n 
B 1 197 ALA 197 257 257 ALA ALA B . n 
B 1 198 LEU 198 258 258 LEU LEU B . n 
B 1 199 TYR 199 259 259 TYR TYR B . n 
B 1 200 THR 200 260 260 THR THR B . n 
B 1 201 ALA 201 261 261 ALA ALA B . n 
B 1 202 LEU 202 262 262 LEU LEU B . n 
B 1 203 GLY 203 263 263 GLY GLY B . n 
B 1 204 GLY 204 264 264 GLY GLY B . n 
B 1 205 VAL 205 265 265 VAL VAL B . n 
B 1 206 ASP 206 266 266 ASP ASP B . n 
B 1 207 PRO 207 267 267 PRO PRO B . n 
B 1 208 SER 208 268 268 SER SER B . n 
B 1 209 VAL 209 269 269 VAL VAL B . n 
B 1 210 CYS 210 270 270 CYS CYS B . n 
B 1 211 LEU 211 271 271 LEU LEU B . n 
B 1 212 PRO 212 272 272 PRO PRO B . n 
B 1 213 ILE 213 273 273 ILE ILE B . n 
B 1 214 THR 214 274 274 THR THR B . n 
B 1 215 ILE 215 275 275 ILE ILE B . n 
B 1 216 ASP 216 276 276 ASP ASP B . n 
B 1 217 VAL 217 277 277 VAL VAL B . n 
B 1 218 GLY 218 278 278 GLY GLY B . n 
B 1 219 THR 219 279 279 THR THR B . n 
B 1 220 ASN 220 280 280 ASN ASN B . n 
B 1 221 ASN 221 281 281 ASN ASN B . n 
B 1 222 GLU 222 282 282 GLU GLU B . n 
B 1 223 LYS 223 283 283 LYS LYS B . n 
B 1 224 LEU 224 284 284 LEU LEU B . n 
B 1 225 LEU 225 285 285 LEU LEU B . n 
B 1 226 ASN 226 286 286 ASN ASN B . n 
B 1 227 ASP 227 287 287 ASP ASP B . n 
B 1 228 GLU 228 288 288 GLU GLU B . n 
B 1 229 PHE 229 289 289 PHE PHE B . n 
B 1 230 TYR 230 290 290 TYR TYR B . n 
B 1 231 ILE 231 291 291 ILE ILE B . n 
B 1 232 GLY 232 292 292 GLY GLY B . n 
B 1 233 LEU 233 293 293 LEU LEU B . n 
B 1 234 ARG 234 294 294 ARG ARG B . n 
B 1 235 GLN 235 295 295 GLN GLN B . n 
B 1 236 LYS 236 296 296 LYS LYS B . n 
B 1 237 ARG 237 297 297 ARG ARG B . n 
B 1 238 ALA 238 298 298 ALA ALA B . n 
B 1 239 THR 239 299 299 THR THR B . n 
B 1 240 GLY 240 300 300 GLY GLY B . n 
B 1 241 GLU 241 301 301 GLU GLU B . n 
B 1 242 GLU 242 302 302 GLU GLU B . n 
B 1 243 TYR 243 303 303 TYR TYR B . n 
B 1 244 ASP 244 304 304 ASP ASP B . n 
B 1 245 GLU 245 305 305 GLU GLU B . n 
B 1 246 LEU 246 306 306 LEU LEU B . n 
B 1 247 ILE 247 307 307 ILE ILE B . n 
B 1 248 GLU 248 308 308 GLU GLU B . n 
B 1 249 GLU 249 309 309 GLU GLU B . n 
B 1 250 PHE 250 310 310 PHE PHE B . n 
B 1 251 MET 251 311 311 MET MET B . n 
B 1 252 SER 252 312 312 SER SER B . n 
B 1 253 ALA 253 313 313 ALA ALA B . n 
B 1 254 VAL 254 314 314 VAL VAL B . n 
B 1 255 LYS 255 315 315 LYS LYS B . n 
B 1 256 GLN 256 316 316 GLN GLN B . n 
B 1 257 PHE 257 317 317 PHE PHE B . n 
B 1 258 TYR 258 318 318 TYR TYR B . n 
B 1 259 GLY 259 319 319 GLY GLY B . n 
B 1 260 GLU 260 320 320 GLU GLU B . n 
B 1 261 LYS 261 321 321 LYS LYS B . n 
B 1 262 VAL 262 322 322 VAL VAL B . n 
B 1 263 LEU 263 323 323 LEU LEU B . n 
B 1 264 ILE 264 324 324 ILE ILE B . n 
B 1 265 GLN 265 325 325 GLN GLN B . n 
B 1 266 PHE 266 326 326 PHE PHE B . n 
B 1 267 GLU 267 327 327 GLU GLU B . n 
B 1 268 ASP 268 328 328 ASP ASP B . n 
B 1 269 PHE 269 329 329 PHE PHE B . n 
B 1 270 ALA 270 330 330 ALA ALA B . n 
B 1 271 ASN 271 331 331 ASN ASN B . n 
B 1 272 HIS 272 332 332 HIS HIS B . n 
B 1 273 ASN 273 333 333 ASN ASN B . n 
B 1 274 ALA 274 334 334 ALA ALA B . n 
B 1 275 PHE 275 335 335 PHE PHE B . n 
B 1 276 ASP 276 336 336 ASP ASP B . n 
B 1 277 LEU 277 337 337 LEU LEU B . n 
B 1 278 LEU 278 338 338 LEU LEU B . n 
B 1 279 GLU 279 339 339 GLU GLU B . n 
B 1 280 LYS 280 340 340 LYS LYS B . n 
B 1 281 TYR 281 341 341 TYR TYR B . n 
B 1 282 SER 282 342 342 SER SER B . n 
B 1 283 LYS 283 343 343 LYS LYS B . n 
B 1 284 SER 284 344 344 SER SER B . n 
B 1 285 HIS 285 345 345 HIS HIS B . n 
B 1 286 LEU 286 346 346 LEU LEU B . n 
B 1 287 VAL 287 347 347 VAL VAL B . n 
B 1 288 PHE 288 348 348 PHE PHE B . n 
B 1 289 ASN 289 349 349 ASN ASN B . n 
B 1 290 ASP 290 350 350 ASP ASP B . n 
B 1 291 ASP 291 351 351 ASP ASP B . n 
B 1 292 ILE 292 352 352 ILE ILE B . n 
B 1 293 GLN 293 353 353 GLN GLN B . n 
B 1 294 GLY 294 354 354 GLY GLY B . n 
B 1 295 THR 295 355 355 THR THR B . n 
B 1 296 ALA 296 356 356 ALA ALA B . n 
B 1 297 SER 297 357 357 SER SER B . n 
B 1 298 VAL 298 358 358 VAL VAL B . n 
B 1 299 VAL 299 359 359 VAL VAL B . n 
B 1 300 LEU 300 360 360 LEU LEU B . n 
B 1 301 ALA 301 361 361 ALA ALA B . n 
B 1 302 GLY 302 362 362 GLY GLY B . n 
B 1 303 LEU 303 363 363 LEU LEU B . n 
B 1 304 LEU 304 364 364 LEU LEU B . n 
B 1 305 ALA 305 365 365 ALA ALA B . n 
B 1 306 ALA 306 366 366 ALA ALA B . n 
B 1 307 LEU 307 367 367 LEU LEU B . n 
B 1 308 LYS 308 368 368 LYS LYS B . n 
B 1 309 MET 309 369 369 MET MET B . n 
B 1 310 VAL 310 370 370 VAL VAL B . n 
B 1 311 GLY 311 371 371 GLY GLY B . n 
B 1 312 GLY 312 372 372 GLY GLY B . n 
B 1 313 THR 313 373 373 THR THR B . n 
B 1 314 LEU 314 374 374 LEU LEU B . n 
B 1 315 ALA 315 375 375 ALA ALA B . n 
B 1 316 GLU 316 376 376 GLU GLU B . n 
B 1 317 GLN 317 377 377 GLN GLN B . n 
B 1 318 THR 318 378 378 THR THR B . n 
B 1 319 TYR 319 379 379 TYR TYR B . n 
B 1 320 LEU 320 380 380 LEU LEU B . n 
B 1 321 PHE 321 381 381 PHE PHE B . n 
B 1 322 LEU 322 382 382 LEU LEU B . n 
B 1 323 GLY 323 383 383 GLY GLY B . n 
B 1 324 ALA 324 384 384 ALA ALA B . n 
B 1 325 GLY 325 385 385 GLY GLY B . n 
B 1 326 GLU 326 386 386 GLU GLU B . n 
B 1 327 ALA 327 387 387 ALA ALA B . n 
B 1 328 GLY 328 388 388 GLY GLY B . n 
B 1 329 THR 329 389 389 THR THR B . n 
B 1 330 GLY 330 390 390 GLY GLY B . n 
B 1 331 ILE 331 391 391 ILE ILE B . n 
B 1 332 ALA 332 392 392 ALA ALA B . n 
B 1 333 GLU 333 393 393 GLU GLU B . n 
B 1 334 LEU 334 394 394 LEU LEU B . n 
B 1 335 ILE 335 395 395 ILE ILE B . n 
B 1 336 ALA 336 396 396 ALA ALA B . n 
B 1 337 LEU 337 397 397 LEU LEU B . n 
B 1 338 GLU 338 398 398 GLU GLU B . n 
B 1 339 ILE 339 399 399 ILE ILE B . n 
B 1 340 SER 340 400 400 SER SER B . n 
B 1 341 LYS 341 401 401 LYS LYS B . n 
B 1 342 GLN 342 402 402 GLN GLN B . n 
B 1 343 THR 343 403 403 THR THR B . n 
B 1 344 ASN 344 404 404 ASN ASN B . n 
B 1 345 ALA 345 405 405 ALA ALA B . n 
B 1 346 PRO 346 406 406 PRO PRO B . n 
B 1 347 ILE 347 407 407 ILE ILE B . n 
B 1 348 GLU 348 408 408 GLU GLU B . n 
B 1 349 GLU 349 409 409 GLU GLU B . n 
B 1 350 CYS 350 410 410 CYS CYS B . n 
B 1 351 ARG 351 411 411 ARG ARG B . n 
B 1 352 LYS 352 412 412 LYS LYS B . n 
B 1 353 LYS 353 413 413 LYS LYS B . n 
B 1 354 VAL 354 414 414 VAL VAL B . n 
B 1 355 TRP 355 415 415 TRP TRP B . n 
B 1 356 LEU 356 416 416 LEU LEU B . n 
B 1 357 VAL 357 417 417 VAL VAL B . n 
B 1 358 ASP 358 418 418 ASP ASP B . n 
B 1 359 SER 359 419 419 SER SER B . n 
B 1 360 LYS 360 420 420 LYS LYS B . n 
B 1 361 GLY 361 421 421 GLY GLY B . n 
B 1 362 LEU 362 422 422 LEU LEU B . n 
B 1 363 ILE 363 423 423 ILE ILE B . n 
B 1 364 VAL 364 424 424 VAL VAL B . n 
B 1 365 ASP 365 425 425 ASP ASP B . n 
B 1 366 SER 366 426 426 SER SER B . n 
B 1 367 ARG 367 427 427 ARG ARG B . n 
B 1 368 LYS 368 428 428 LYS LYS B . n 
B 1 369 GLY 369 429 429 GLY GLY B . n 
B 1 370 SER 370 430 430 SER SER B . n 
B 1 371 LEU 371 431 431 LEU LEU B . n 
B 1 372 GLN 372 432 432 GLN GLN B . n 
B 1 373 PRO 373 433 433 PRO PRO B . n 
B 1 374 PHE 374 434 434 PHE PHE B . n 
B 1 375 LYS 375 435 435 LYS LYS B . n 
B 1 376 LYS 376 436 436 LYS LYS B . n 
B 1 377 PRO 377 437 437 PRO PRO B . n 
B 1 378 TRP 378 438 438 TRP TRP B . n 
B 1 379 ALA 379 439 439 ALA ALA B . n 
B 1 380 HIS 380 440 440 HIS HIS B . n 
B 1 381 GLU 381 441 441 GLU GLU B . n 
B 1 382 HIS 382 442 442 HIS HIS B . n 
B 1 383 GLU 383 443 443 GLU GLU B . n 
B 1 384 PRO 384 444 444 PRO PRO B . n 
B 1 385 LEU 385 445 445 LEU LEU B . n 
B 1 386 LYS 386 446 446 LYS LYS B . n 
B 1 387 THR 387 447 447 THR THR B . n 
B 1 388 LEU 388 448 448 LEU LEU B . n 
B 1 389 TYR 389 449 449 TYR TYR B . n 
B 1 390 ASP 390 450 450 ASP ASP B . n 
B 1 391 ALA 391 451 451 ALA ALA B . n 
B 1 392 VAL 392 452 452 VAL VAL B . n 
B 1 393 GLN 393 453 453 GLN GLN B . n 
B 1 394 SER 394 454 454 SER SER B . n 
B 1 395 ILE 395 455 455 ILE ILE B . n 
B 1 396 LYS 396 456 456 LYS LYS B . n 
B 1 397 PRO 397 457 457 PRO PRO B . n 
B 1 398 THR 398 458 458 THR THR B . n 
B 1 399 VAL 399 459 459 VAL VAL B . n 
B 1 400 LEU 400 460 460 LEU LEU B . n 
B 1 401 ILE 401 461 461 ILE ILE B . n 
B 1 402 GLY 402 462 462 GLY GLY B . n 
B 1 403 THR 403 463 463 THR THR B . n 
B 1 404 SER 404 464 464 SER SER B . n 
B 1 405 GLY 405 465 465 GLY GLY B . n 
B 1 406 VAL 406 466 466 VAL VAL B . n 
B 1 407 GLY 407 467 467 GLY GLY B . n 
B 1 408 ARG 408 468 468 ARG ARG B . n 
B 1 409 THR 409 469 469 THR THR B . n 
B 1 410 PHE 410 470 470 PHE PHE B . n 
B 1 411 THR 411 471 471 THR THR B . n 
B 1 412 LYS 412 472 472 LYS LYS B . n 
B 1 413 GLU 413 473 473 GLU GLU B . n 
B 1 414 ILE 414 474 474 ILE ILE B . n 
B 1 415 ILE 415 475 475 ILE ILE B . n 
B 1 416 GLU 416 476 476 GLU GLU B . n 
B 1 417 ALA 417 477 477 ALA ALA B . n 
B 1 418 MET 418 478 478 MET MET B . n 
B 1 419 SER 419 479 479 SER SER B . n 
B 1 420 SER 420 480 480 SER SER B . n 
B 1 421 PHE 421 481 481 PHE PHE B . n 
B 1 422 ASN 422 482 482 ASN ASN B . n 
B 1 423 GLU 423 483 483 GLU GLU B . n 
B 1 424 ARG 424 484 484 ARG ARG B . n 
B 1 425 PRO 425 485 485 PRO PRO B . n 
B 1 426 ILE 426 486 486 ILE ILE B . n 
B 1 427 ILE 427 487 487 ILE ILE B . n 
B 1 428 PHE 428 488 488 PHE PHE B . n 
B 1 429 SER 429 489 489 SER SER B . n 
B 1 430 LEU 430 490 490 LEU LEU B . n 
B 1 431 SER 431 491 491 SER SER B . n 
B 1 432 ASN 432 492 492 ASN ASN B . n 
B 1 433 PRO 433 493 493 PRO PRO B . n 
B 1 434 THR 434 494 494 THR THR B . n 
B 1 435 SER 435 495 495 SER SER B . n 
B 1 436 HIS 436 496 496 HIS HIS B . n 
B 1 437 SER 437 497 497 SER SER B . n 
B 1 438 GLU 438 498 498 GLU GLU B . n 
B 1 439 CYS 439 499 499 CYS CYS B . n 
B 1 440 THR 440 500 500 THR THR B . n 
B 1 441 ALA 441 501 501 ALA ALA B . n 
B 1 442 GLU 442 502 502 GLU GLU B . n 
B 1 443 GLN 443 503 503 GLN GLN B . n 
B 1 444 ALA 444 504 504 ALA ALA B . n 
B 1 445 TYR 445 505 505 TYR TYR B . n 
B 1 446 THR 446 506 506 THR THR B . n 
B 1 447 TRP 447 507 507 TRP TRP B . n 
B 1 448 SER 448 508 508 SER SER B . n 
B 1 449 GLN 449 509 509 GLN GLN B . n 
B 1 450 GLY 450 510 510 GLY GLY B . n 
B 1 451 ARG 451 511 511 ARG ARG B . n 
B 1 452 SER 452 512 512 SER SER B . n 
B 1 453 ILE 453 513 513 ILE ILE B . n 
B 1 454 PHE 454 514 514 PHE PHE B . n 
B 1 455 ALA 455 515 515 ALA ALA B . n 
B 1 456 SER 456 516 516 SER SER B . n 
B 1 457 GLY 457 517 517 GLY GLY B . n 
B 1 458 SER 458 518 518 SER SER B . n 
B 1 459 PRO 459 519 519 PRO PRO B . n 
B 1 460 PHE 460 520 520 PHE PHE B . n 
B 1 461 ALA 461 521 521 ALA ALA B . n 
B 1 462 PRO 462 522 522 PRO PRO B . n 
B 1 463 VAL 463 523 523 VAL VAL B . n 
B 1 464 GLU 464 524 524 GLU GLU B . n 
B 1 465 TYR 465 525 525 TYR TYR B . n 
B 1 466 GLU 466 526 526 GLU GLU B . n 
B 1 467 GLY 467 527 527 GLY GLY B . n 
B 1 468 LYS 468 528 528 LYS LYS B . n 
B 1 469 THR 469 529 529 THR THR B . n 
B 1 470 PHE 470 530 530 PHE PHE B . n 
B 1 471 VAL 471 531 531 VAL VAL B . n 
B 1 472 PRO 472 532 532 PRO PRO B . n 
B 1 473 GLY 473 533 533 GLY GLY B . n 
B 1 474 GLN 474 534 534 GLN GLN B . n 
B 1 475 SER 475 535 535 SER SER B . n 
B 1 476 ASN 476 536 536 ASN ASN B . n 
B 1 477 ASN 477 537 537 ASN ASN B . n 
B 1 478 ALA 478 538 538 ALA ALA B . n 
B 1 479 TYR 479 539 539 TYR TYR B . n 
B 1 480 ILE 480 540 540 ILE ILE B . n 
B 1 481 PHE 481 541 541 PHE PHE B . n 
B 1 482 PRO 482 542 542 PRO PRO B . n 
B 1 483 GLY 483 543 543 GLY GLY B . n 
B 1 484 LEU 484 544 544 LEU LEU B . n 
B 1 485 GLY 485 545 545 GLY GLY B . n 
B 1 486 LEU 486 546 546 LEU LEU B . n 
B 1 487 GLY 487 547 547 GLY GLY B . n 
B 1 488 LEU 488 548 548 LEU LEU B . n 
B 1 489 VAL 489 549 549 VAL VAL B . n 
B 1 490 ILE 490 550 550 ILE ILE B . n 
B 1 491 SER 491 551 551 SER SER B . n 
B 1 492 GLY 492 552 552 GLY GLY B . n 
B 1 493 ALA 493 553 553 ALA ALA B . n 
B 1 494 VAL 494 554 554 VAL VAL B . n 
B 1 495 ARG 495 555 555 ARG ARG B . n 
B 1 496 VAL 496 556 556 VAL VAL B . n 
B 1 497 HIS 497 557 557 HIS HIS B . n 
B 1 498 GLU 498 558 558 GLU GLU B . n 
B 1 499 ASP 499 559 559 ASP ASP B . n 
B 1 500 MET 500 560 560 MET MET B . n 
B 1 501 LEU 501 561 561 LEU LEU B . n 
B 1 502 LEU 502 562 562 LEU LEU B . n 
B 1 503 ALA 503 563 563 ALA ALA B . n 
B 1 504 ALA 504 564 564 ALA ALA B . n 
B 1 505 SER 505 565 565 SER SER B . n 
B 1 506 LYS 506 566 566 LYS LYS B . n 
B 1 507 ALA 507 567 567 ALA ALA B . n 
B 1 508 LEU 508 568 568 LEU LEU B . n 
B 1 509 ALA 509 569 569 ALA ALA B . n 
B 1 510 ASP 510 570 570 ASP ASP B . n 
B 1 511 GLN 511 571 571 GLN GLN B . n 
B 1 512 ALA 512 572 572 ALA ALA B . n 
B 1 513 THR 513 573 573 THR THR B . n 
B 1 514 GLN 514 574 574 GLN GLN B . n 
B 1 515 ASP 515 575 575 ASP ASP B . n 
B 1 516 ASN 516 576 576 ASN ASN B . n 
B 1 517 PHE 517 577 577 PHE PHE B . n 
B 1 518 GLU 518 578 578 GLU GLU B . n 
B 1 519 LYS 519 579 579 LYS LYS B . n 
B 1 520 GLY 520 580 580 GLY GLY B . n 
B 1 521 SER 521 581 581 SER SER B . n 
B 1 522 ILE 522 582 582 ILE ILE B . n 
B 1 523 PHE 523 583 583 PHE PHE B . n 
B 1 524 PRO 524 584 584 PRO PRO B . n 
B 1 525 PRO 525 585 585 PRO PRO B . n 
B 1 526 PHE 526 586 586 PHE PHE B . n 
B 1 527 THR 527 587 587 THR THR B . n 
B 1 528 SER 528 588 588 SER SER B . n 
B 1 529 ILE 529 589 589 ILE ILE B . n 
B 1 530 ARG 530 590 590 ARG ARG B . n 
B 1 531 LYS 531 591 591 LYS LYS B . n 
B 1 532 ILE 532 592 592 ILE ILE B . n 
B 1 533 SER 533 593 593 SER SER B . n 
B 1 534 ALA 534 594 594 ALA ALA B . n 
B 1 535 HIS 535 595 595 HIS HIS B . n 
B 1 536 ILE 536 596 596 ILE ILE B . n 
B 1 537 ALA 537 597 597 ALA ALA B . n 
B 1 538 ALA 538 598 598 ALA ALA B . n 
B 1 539 ALA 539 599 599 ALA ALA B . n 
B 1 540 VAL 540 600 600 VAL VAL B . n 
B 1 541 ALA 541 601 601 ALA ALA B . n 
B 1 542 ALA 542 602 602 ALA ALA B . n 
B 1 543 LYS 543 603 603 LYS LYS B . n 
B 1 544 ALA 544 604 604 ALA ALA B . n 
B 1 545 TYR 545 605 605 TYR TYR B . n 
B 1 546 GLU 546 606 606 GLU GLU B . n 
B 1 547 LEU 547 607 607 LEU LEU B . n 
B 1 548 GLY 548 608 608 GLY GLY B . n 
B 1 549 LEU 549 609 609 LEU LEU B . n 
B 1 550 ALA 550 610 610 ALA ALA B . n 
B 1 551 THR 551 611 611 THR THR B . n 
B 1 552 ARG 552 612 612 ARG ARG B . n 
B 1 553 LEU 553 613 613 LEU LEU B . n 
B 1 554 PRO 554 614 614 PRO PRO B . n 
B 1 555 PRO 555 615 615 PRO PRO B . n 
B 1 556 PRO 556 616 616 PRO PRO B . n 
B 1 557 SER 557 617 617 SER SER B . n 
B 1 558 ASP 558 618 618 ASP ASP B . n 
B 1 559 LEU 559 619 619 LEU LEU B . n 
B 1 560 VAL 560 620 620 VAL VAL B . n 
B 1 561 LYS 561 621 621 LYS LYS B . n 
B 1 562 TYR 562 622 622 TYR TYR B . n 
B 1 563 ALA 563 623 623 ALA ALA B . n 
B 1 564 GLU 564 624 624 GLU GLU B . n 
B 1 565 ASN 565 625 625 ASN ASN B . n 
B 1 566 CYS 566 626 626 CYS CYS B . n 
B 1 567 MET 567 627 627 MET MET B . n 
B 1 568 TYR 568 628 628 TYR TYR B . n 
B 1 569 THR 569 629 629 THR THR B . n 
B 1 570 PRO 570 630 630 PRO PRO B . n 
B 1 571 VAL 571 631 631 VAL VAL B . n 
B 1 572 TYR 572 632 632 TYR TYR B . n 
B 1 573 ARG 573 633 633 ARG ARG B . n 
B 1 574 ASN 574 634 634 ASN ASN B . n 
B 1 575 TYR 575 635 635 TYR TYR B . n 
B 1 576 ARG 576 636 636 ARG ARG B . n 
C 1 1   HIS 1   61  ?   ?   ?   C . n 
C 1 2   ALA 2   62  ?   ?   ?   C . n 
C 1 3   MET 3   63  ?   ?   ?   C . n 
C 1 4   VAL 4   64  ?   ?   ?   C . n 
C 1 5   SER 5   65  ?   ?   ?   C . n 
C 1 6   ASN 6   66  ?   ?   ?   C . n 
C 1 7   ALA 7   67  ?   ?   ?   C . n 
C 1 8   GLU 8   68  ?   ?   ?   C . n 
C 1 9   THR 9   69  ?   ?   ?   C . n 
C 1 10  GLU 10  70  ?   ?   ?   C . n 
C 1 11  THR 11  71  ?   ?   ?   C . n 
C 1 12  GLU 12  72  ?   ?   ?   C . n 
C 1 13  LYS 13  73  ?   ?   ?   C . n 
C 1 14  GLU 14  74  ?   ?   ?   C . n 
C 1 15  GLN 15  75  ?   ?   ?   C . n 
C 1 16  GLU 16  76  ?   ?   ?   C . n 
C 1 17  GLU 17  77  ?   ?   ?   C . n 
C 1 18  ALA 18  78  ?   ?   ?   C . n 
C 1 19  ALA 19  79  ?   ?   ?   C . n 
C 1 20  ALA 20  80  ?   ?   ?   C . n 
C 1 21  ALA 21  81  ?   ?   ?   C . n 
C 1 22  SER 22  82  ?   ?   ?   C . n 
C 1 23  GLU 23  83  ?   ?   ?   C . n 
C 1 24  GLU 24  84  ?   ?   ?   C . n 
C 1 25  LEU 25  85  85  LEU LEU C . n 
C 1 26  PRO 26  86  86  PRO PRO C . n 
C 1 27  VAL 27  87  87  VAL VAL C . n 
C 1 28  MET 28  88  88  MET MET C . n 
C 1 29  PRO 29  89  89  PRO PRO C . n 
C 1 30  TRP 30  90  90  TRP TRP C . n 
C 1 31  ALA 31  91  91  ALA ALA C . n 
C 1 32  THR 32  92  92  THR THR C . n 
C 1 33  SER 33  93  93  SER SER C . n 
C 1 34  VAL 34  94  94  VAL VAL C . n 
C 1 35  ALA 35  95  95  ALA ALA C . n 
C 1 36  SER 36  96  96  SER SER C . n 
C 1 37  GLY 37  97  97  GLY GLY C . n 
C 1 38  TYR 38  98  98  TYR TYR C . n 
C 1 39  THR 39  99  99  THR THR C . n 
C 1 40  LEU 40  100 100 LEU LEU C . n 
C 1 41  LEU 41  101 101 LEU LEU C . n 
C 1 42  ARG 42  102 102 ARG ARG C . n 
C 1 43  ASP 43  103 103 ASP ASP C . n 
C 1 44  PRO 44  104 104 PRO PRO C . n 
C 1 45  HIS 45  105 105 HIS HIS C . n 
C 1 46  HIS 46  106 106 HIS HIS C . n 
C 1 47  ASN 47  107 107 ASN ASN C . n 
C 1 48  LYS 48  108 108 LYS LYS C . n 
C 1 49  GLY 49  109 109 GLY GLY C . n 
C 1 50  LEU 50  110 110 LEU LEU C . n 
C 1 51  ALA 51  111 111 ALA ALA C . n 
C 1 52  PHE 52  112 112 PHE PHE C . n 
C 1 53  THR 53  113 113 THR THR C . n 
C 1 54  GLU 54  114 114 GLU GLU C . n 
C 1 55  GLU 55  115 115 GLU GLU C . n 
C 1 56  GLU 56  116 116 GLU GLU C . n 
C 1 57  ARG 57  117 117 ARG ARG C . n 
C 1 58  ASP 58  118 118 ASP ASP C . n 
C 1 59  GLY 59  119 119 GLY GLY C . n 
C 1 60  HIS 60  120 120 HIS HIS C . n 
C 1 61  TYR 61  121 121 TYR TYR C . n 
C 1 62  LEU 62  122 122 LEU LEU C . n 
C 1 63  ARG 63  123 123 ARG ARG C . n 
C 1 64  GLY 64  124 124 GLY GLY C . n 
C 1 65  LEU 65  125 125 LEU LEU C . n 
C 1 66  LEU 66  126 126 LEU LEU C . n 
C 1 67  PRO 67  127 127 PRO PRO C . n 
C 1 68  PRO 68  128 128 PRO PRO C . n 
C 1 69  ALA 69  129 129 ALA ALA C . n 
C 1 70  VAL 70  130 130 VAL VAL C . n 
C 1 71  LEU 71  131 131 LEU LEU C . n 
C 1 72  SER 72  132 132 SER SER C . n 
C 1 73  GLN 73  133 133 GLN GLN C . n 
C 1 74  GLU 74  134 134 GLU GLU C . n 
C 1 75  LEU 75  135 135 LEU LEU C . n 
C 1 76  GLN 76  136 136 GLN GLN C . n 
C 1 77  ILE 77  137 137 ILE ILE C . n 
C 1 78  LYS 78  138 138 LYS LYS C . n 
C 1 79  LYS 79  139 139 LYS LYS C . n 
C 1 80  PHE 80  140 140 PHE PHE C . n 
C 1 81  MET 81  141 141 MET MET C . n 
C 1 82  ASN 82  142 142 ASN ASN C . n 
C 1 83  THR 83  143 143 THR THR C . n 
C 1 84  LEU 84  144 144 LEU LEU C . n 
C 1 85  ARG 85  145 145 ARG ARG C . n 
C 1 86  GLN 86  146 146 GLN GLN C . n 
C 1 87  TYR 87  147 147 TYR TYR C . n 
C 1 88  GLN 88  148 148 GLN GLN C . n 
C 1 89  THR 89  149 149 THR THR C . n 
C 1 90  PRO 90  150 150 PRO PRO C . n 
C 1 91  LEU 91  151 151 LEU LEU C . n 
C 1 92  GLN 92  152 152 GLN GLN C . n 
C 1 93  ARG 93  153 153 ARG ARG C . n 
C 1 94  TYR 94  154 154 TYR TYR C . n 
C 1 95  ILE 95  155 155 ILE ILE C . n 
C 1 96  ALA 96  156 156 ALA ALA C . n 
C 1 97  MET 97  157 157 MET MET C . n 
C 1 98  MET 98  158 158 MET MET C . n 
C 1 99  ASN 99  159 159 ASN ASN C . n 
C 1 100 LEU 100 160 160 LEU LEU C . n 
C 1 101 GLN 101 161 161 GLN GLN C . n 
C 1 102 GLU 102 162 162 GLU GLU C . n 
C 1 103 THR 103 163 163 THR THR C . n 
C 1 104 ASP 104 164 164 ASP ASP C . n 
C 1 105 GLU 105 165 165 GLU GLU C . n 
C 1 106 ARG 106 166 166 ARG ARG C . n 
C 1 107 LEU 107 167 167 LEU LEU C . n 
C 1 108 PHE 108 168 168 PHE PHE C . n 
C 1 109 TYR 109 169 169 TYR TYR C . n 
C 1 110 LYS 110 170 170 LYS LYS C . n 
C 1 111 LEU 111 171 171 LEU LEU C . n 
C 1 112 LEU 112 172 172 LEU LEU C . n 
C 1 113 ILE 113 173 173 ILE ILE C . n 
C 1 114 ASP 114 174 174 ASP ASP C . n 
C 1 115 ASN 115 175 175 ASN ASN C . n 
C 1 116 VAL 116 176 176 VAL VAL C . n 
C 1 117 VAL 117 177 177 VAL VAL C . n 
C 1 118 GLU 118 178 178 GLU GLU C . n 
C 1 119 LEU 119 179 179 LEU LEU C . n 
C 1 120 LEU 120 180 180 LEU LEU C . n 
C 1 121 PRO 121 181 181 PRO PRO C . n 
C 1 122 PHE 122 182 182 PHE PHE C . n 
C 1 123 VAL 123 183 183 VAL VAL C . n 
C 1 124 TYR 124 184 184 TYR TYR C . n 
C 1 125 THR 125 185 185 THR THR C . n 
C 1 126 PRO 126 186 186 PRO PRO C . n 
C 1 127 THR 127 187 187 THR THR C . n 
C 1 128 VAL 128 188 188 VAL VAL C . n 
C 1 129 GLY 129 189 189 GLY GLY C . n 
C 1 130 GLU 130 190 190 GLU GLU C . n 
C 1 131 ALA 131 191 191 ALA ALA C . n 
C 1 132 CYS 132 192 192 CYS CYS C . n 
C 1 133 GLN 133 193 193 GLN GLN C . n 
C 1 134 LYS 134 194 194 LYS LYS C . n 
C 1 135 TYR 135 195 195 TYR TYR C . n 
C 1 136 GLY 136 196 196 GLY GLY C . n 
C 1 137 SER 137 197 197 SER SER C . n 
C 1 138 ILE 138 198 198 ILE ILE C . n 
C 1 139 PHE 139 199 199 PHE PHE C . n 
C 1 140 ARG 140 200 200 ARG ARG C . n 
C 1 141 ARG 141 201 201 ARG ARG C . n 
C 1 142 PRO 142 202 202 PRO PRO C . n 
C 1 143 GLN 143 203 203 GLN GLN C . n 
C 1 144 GLY 144 204 204 GLY GLY C . n 
C 1 145 LEU 145 205 205 LEU LEU C . n 
C 1 146 TYR 146 206 206 TYR TYR C . n 
C 1 147 VAL 147 207 207 VAL VAL C . n 
C 1 148 SER 148 208 208 SER SER C . n 
C 1 149 LEU 149 209 209 LEU LEU C . n 
C 1 150 LYS 150 210 210 LYS LYS C . n 
C 1 151 ASP 151 211 211 ASP ASP C . n 
C 1 152 LYS 152 212 212 LYS LYS C . n 
C 1 153 GLY 153 213 213 GLY GLY C . n 
C 1 154 LYS 154 214 214 LYS LYS C . n 
C 1 155 VAL 155 215 215 VAL VAL C . n 
C 1 156 LEU 156 216 216 LEU LEU C . n 
C 1 157 GLU 157 217 217 GLU GLU C . n 
C 1 158 VAL 158 218 218 VAL VAL C . n 
C 1 159 LEU 159 219 219 LEU LEU C . n 
C 1 160 ARG 160 220 220 ARG ARG C . n 
C 1 161 ASN 161 221 221 ASN ASN C . n 
C 1 162 TRP 162 222 222 TRP TRP C . n 
C 1 163 PRO 163 223 223 PRO PRO C . n 
C 1 164 HIS 164 224 224 HIS HIS C . n 
C 1 165 ARG 165 225 225 ARG ARG C . n 
C 1 166 ASN 166 226 226 ASN ASN C . n 
C 1 167 ILE 167 227 227 ILE ILE C . n 
C 1 168 GLN 168 228 228 GLN GLN C . n 
C 1 169 VAL 169 229 229 VAL VAL C . n 
C 1 170 ILE 170 230 230 ILE ILE C . n 
C 1 171 CYS 171 231 231 CYS CYS C . n 
C 1 172 VAL 172 232 232 VAL VAL C . n 
C 1 173 THR 173 233 233 THR THR C . n 
C 1 174 ASP 174 234 234 ASP ASP C . n 
C 1 175 GLY 175 235 235 GLY GLY C . n 
C 1 176 GLU 176 236 236 GLU GLU C . n 
C 1 177 ARG 177 237 237 ARG ARG C . n 
C 1 178 ILE 178 238 238 ILE ILE C . n 
C 1 179 LEU 179 239 239 LEU LEU C . n 
C 1 180 GLY 180 240 240 GLY GLY C . n 
C 1 181 LEU 181 241 241 LEU LEU C . n 
C 1 182 GLY 182 242 242 GLY GLY C . n 
C 1 183 ASP 183 243 243 ASP ASP C . n 
C 1 184 LEU 184 244 244 LEU LEU C . n 
C 1 185 GLY 185 245 245 GLY GLY C . n 
C 1 186 CYS 186 246 246 CYS CYS C . n 
C 1 187 GLN 187 247 247 GLN GLN C . n 
C 1 188 GLY 188 248 248 GLY GLY C . n 
C 1 189 MET 189 249 249 MET MET C . n 
C 1 190 GLY 190 250 250 GLY GLY C . n 
C 1 191 ILE 191 251 251 ILE ILE C . n 
C 1 192 PRO 192 252 252 PRO PRO C . n 
C 1 193 VAL 193 253 253 VAL VAL C . n 
C 1 194 GLY 194 254 254 GLY GLY C . n 
C 1 195 LYS 195 255 255 LYS LYS C . n 
C 1 196 LEU 196 256 256 LEU LEU C . n 
C 1 197 ALA 197 257 257 ALA ALA C . n 
C 1 198 LEU 198 258 258 LEU LEU C . n 
C 1 199 TYR 199 259 259 TYR TYR C . n 
C 1 200 THR 200 260 260 THR THR C . n 
C 1 201 ALA 201 261 261 ALA ALA C . n 
C 1 202 LEU 202 262 262 LEU LEU C . n 
C 1 203 GLY 203 263 263 GLY GLY C . n 
C 1 204 GLY 204 264 264 GLY GLY C . n 
C 1 205 VAL 205 265 265 VAL VAL C . n 
C 1 206 ASP 206 266 266 ASP ASP C . n 
C 1 207 PRO 207 267 267 PRO PRO C . n 
C 1 208 SER 208 268 268 SER SER C . n 
C 1 209 VAL 209 269 269 VAL VAL C . n 
C 1 210 CYS 210 270 270 CYS CYS C . n 
C 1 211 LEU 211 271 271 LEU LEU C . n 
C 1 212 PRO 212 272 272 PRO PRO C . n 
C 1 213 ILE 213 273 273 ILE ILE C . n 
C 1 214 THR 214 274 274 THR THR C . n 
C 1 215 ILE 215 275 275 ILE ILE C . n 
C 1 216 ASP 216 276 276 ASP ASP C . n 
C 1 217 VAL 217 277 277 VAL VAL C . n 
C 1 218 GLY 218 278 278 GLY GLY C . n 
C 1 219 THR 219 279 279 THR THR C . n 
C 1 220 ASN 220 280 280 ASN ASN C . n 
C 1 221 ASN 221 281 281 ASN ASN C . n 
C 1 222 GLU 222 282 282 GLU GLU C . n 
C 1 223 LYS 223 283 283 LYS LYS C . n 
C 1 224 LEU 224 284 284 LEU LEU C . n 
C 1 225 LEU 225 285 285 LEU LEU C . n 
C 1 226 ASN 226 286 286 ASN ASN C . n 
C 1 227 ASP 227 287 287 ASP ASP C . n 
C 1 228 GLU 228 288 288 GLU GLU C . n 
C 1 229 PHE 229 289 289 PHE PHE C . n 
C 1 230 TYR 230 290 290 TYR TYR C . n 
C 1 231 ILE 231 291 291 ILE ILE C . n 
C 1 232 GLY 232 292 292 GLY GLY C . n 
C 1 233 LEU 233 293 293 LEU LEU C . n 
C 1 234 ARG 234 294 294 ARG ARG C . n 
C 1 235 GLN 235 295 295 GLN GLN C . n 
C 1 236 LYS 236 296 296 LYS LYS C . n 
C 1 237 ARG 237 297 297 ARG ARG C . n 
C 1 238 ALA 238 298 298 ALA ALA C . n 
C 1 239 THR 239 299 299 THR THR C . n 
C 1 240 GLY 240 300 300 GLY GLY C . n 
C 1 241 GLU 241 301 301 GLU GLU C . n 
C 1 242 GLU 242 302 302 GLU GLU C . n 
C 1 243 TYR 243 303 303 TYR TYR C . n 
C 1 244 ASP 244 304 304 ASP ASP C . n 
C 1 245 GLU 245 305 305 GLU GLU C . n 
C 1 246 LEU 246 306 306 LEU LEU C . n 
C 1 247 ILE 247 307 307 ILE ILE C . n 
C 1 248 GLU 248 308 308 GLU GLU C . n 
C 1 249 GLU 249 309 309 GLU GLU C . n 
C 1 250 PHE 250 310 310 PHE PHE C . n 
C 1 251 MET 251 311 311 MET MET C . n 
C 1 252 SER 252 312 312 SER SER C . n 
C 1 253 ALA 253 313 313 ALA ALA C . n 
C 1 254 VAL 254 314 314 VAL VAL C . n 
C 1 255 LYS 255 315 315 LYS LYS C . n 
C 1 256 GLN 256 316 316 GLN GLN C . n 
C 1 257 PHE 257 317 317 PHE PHE C . n 
C 1 258 TYR 258 318 318 TYR TYR C . n 
C 1 259 GLY 259 319 319 GLY GLY C . n 
C 1 260 GLU 260 320 320 GLU GLU C . n 
C 1 261 LYS 261 321 321 LYS LYS C . n 
C 1 262 VAL 262 322 322 VAL VAL C . n 
C 1 263 LEU 263 323 323 LEU LEU C . n 
C 1 264 ILE 264 324 324 ILE ILE C . n 
C 1 265 GLN 265 325 325 GLN GLN C . n 
C 1 266 PHE 266 326 326 PHE PHE C . n 
C 1 267 GLU 267 327 327 GLU GLU C . n 
C 1 268 ASP 268 328 328 ASP ASP C . n 
C 1 269 PHE 269 329 329 PHE PHE C . n 
C 1 270 ALA 270 330 330 ALA ALA C . n 
C 1 271 ASN 271 331 331 ASN ASN C . n 
C 1 272 HIS 272 332 332 HIS HIS C . n 
C 1 273 ASN 273 333 333 ASN ASN C . n 
C 1 274 ALA 274 334 334 ALA ALA C . n 
C 1 275 PHE 275 335 335 PHE PHE C . n 
C 1 276 ASP 276 336 336 ASP ASP C . n 
C 1 277 LEU 277 337 337 LEU LEU C . n 
C 1 278 LEU 278 338 338 LEU LEU C . n 
C 1 279 GLU 279 339 339 GLU GLU C . n 
C 1 280 LYS 280 340 340 LYS LYS C . n 
C 1 281 TYR 281 341 341 TYR TYR C . n 
C 1 282 SER 282 342 342 SER SER C . n 
C 1 283 LYS 283 343 343 LYS LYS C . n 
C 1 284 SER 284 344 344 SER SER C . n 
C 1 285 HIS 285 345 345 HIS HIS C . n 
C 1 286 LEU 286 346 346 LEU LEU C . n 
C 1 287 VAL 287 347 347 VAL VAL C . n 
C 1 288 PHE 288 348 348 PHE PHE C . n 
C 1 289 ASN 289 349 349 ASN ASN C . n 
C 1 290 ASP 290 350 350 ASP ASP C . n 
C 1 291 ASP 291 351 351 ASP ASP C . n 
C 1 292 ILE 292 352 352 ILE ILE C . n 
C 1 293 GLN 293 353 353 GLN GLN C . n 
C 1 294 GLY 294 354 354 GLY GLY C . n 
C 1 295 THR 295 355 355 THR THR C . n 
C 1 296 ALA 296 356 356 ALA ALA C . n 
C 1 297 SER 297 357 357 SER SER C . n 
C 1 298 VAL 298 358 358 VAL VAL C . n 
C 1 299 VAL 299 359 359 VAL VAL C . n 
C 1 300 LEU 300 360 360 LEU LEU C . n 
C 1 301 ALA 301 361 361 ALA ALA C . n 
C 1 302 GLY 302 362 362 GLY GLY C . n 
C 1 303 LEU 303 363 363 LEU LEU C . n 
C 1 304 LEU 304 364 364 LEU LEU C . n 
C 1 305 ALA 305 365 365 ALA ALA C . n 
C 1 306 ALA 306 366 366 ALA ALA C . n 
C 1 307 LEU 307 367 367 LEU LEU C . n 
C 1 308 LYS 308 368 368 LYS LYS C . n 
C 1 309 MET 309 369 369 MET MET C . n 
C 1 310 VAL 310 370 370 VAL VAL C . n 
C 1 311 GLY 311 371 371 GLY GLY C . n 
C 1 312 GLY 312 372 372 GLY GLY C . n 
C 1 313 THR 313 373 373 THR THR C . n 
C 1 314 LEU 314 374 374 LEU LEU C . n 
C 1 315 ALA 315 375 375 ALA ALA C . n 
C 1 316 GLU 316 376 376 GLU GLU C . n 
C 1 317 GLN 317 377 377 GLN GLN C . n 
C 1 318 THR 318 378 378 THR THR C . n 
C 1 319 TYR 319 379 379 TYR TYR C . n 
C 1 320 LEU 320 380 380 LEU LEU C . n 
C 1 321 PHE 321 381 381 PHE PHE C . n 
C 1 322 LEU 322 382 382 LEU LEU C . n 
C 1 323 GLY 323 383 383 GLY GLY C . n 
C 1 324 ALA 324 384 384 ALA ALA C . n 
C 1 325 GLY 325 385 385 GLY GLY C . n 
C 1 326 GLU 326 386 386 GLU GLU C . n 
C 1 327 ALA 327 387 387 ALA ALA C . n 
C 1 328 GLY 328 388 388 GLY GLY C . n 
C 1 329 THR 329 389 389 THR THR C . n 
C 1 330 GLY 330 390 390 GLY GLY C . n 
C 1 331 ILE 331 391 391 ILE ILE C . n 
C 1 332 ALA 332 392 392 ALA ALA C . n 
C 1 333 GLU 333 393 393 GLU GLU C . n 
C 1 334 LEU 334 394 394 LEU LEU C . n 
C 1 335 ILE 335 395 395 ILE ILE C . n 
C 1 336 ALA 336 396 396 ALA ALA C . n 
C 1 337 LEU 337 397 397 LEU LEU C . n 
C 1 338 GLU 338 398 398 GLU GLU C . n 
C 1 339 ILE 339 399 399 ILE ILE C . n 
C 1 340 SER 340 400 400 SER SER C . n 
C 1 341 LYS 341 401 401 LYS LYS C . n 
C 1 342 GLN 342 402 402 GLN GLN C . n 
C 1 343 THR 343 403 403 THR THR C . n 
C 1 344 ASN 344 404 404 ASN ASN C . n 
C 1 345 ALA 345 405 405 ALA ALA C . n 
C 1 346 PRO 346 406 406 PRO PRO C . n 
C 1 347 ILE 347 407 407 ILE ILE C . n 
C 1 348 GLU 348 408 408 GLU GLU C . n 
C 1 349 GLU 349 409 409 GLU GLU C . n 
C 1 350 CYS 350 410 410 CYS CYS C . n 
C 1 351 ARG 351 411 411 ARG ARG C . n 
C 1 352 LYS 352 412 412 LYS LYS C . n 
C 1 353 LYS 353 413 413 LYS LYS C . n 
C 1 354 VAL 354 414 414 VAL VAL C . n 
C 1 355 TRP 355 415 415 TRP TRP C . n 
C 1 356 LEU 356 416 416 LEU LEU C . n 
C 1 357 VAL 357 417 417 VAL VAL C . n 
C 1 358 ASP 358 418 418 ASP ASP C . n 
C 1 359 SER 359 419 419 SER SER C . n 
C 1 360 LYS 360 420 420 LYS LYS C . n 
C 1 361 GLY 361 421 421 GLY GLY C . n 
C 1 362 LEU 362 422 422 LEU LEU C . n 
C 1 363 ILE 363 423 423 ILE ILE C . n 
C 1 364 VAL 364 424 424 VAL VAL C . n 
C 1 365 ASP 365 425 425 ASP ASP C . n 
C 1 366 SER 366 426 426 SER SER C . n 
C 1 367 ARG 367 427 427 ARG ARG C . n 
C 1 368 LYS 368 428 428 LYS LYS C . n 
C 1 369 GLY 369 429 429 GLY GLY C . n 
C 1 370 SER 370 430 430 SER SER C . n 
C 1 371 LEU 371 431 431 LEU LEU C . n 
C 1 372 GLN 372 432 432 GLN GLN C . n 
C 1 373 PRO 373 433 433 PRO PRO C . n 
C 1 374 PHE 374 434 434 PHE PHE C . n 
C 1 375 LYS 375 435 435 LYS LYS C . n 
C 1 376 LYS 376 436 436 LYS LYS C . n 
C 1 377 PRO 377 437 437 PRO PRO C . n 
C 1 378 TRP 378 438 438 TRP TRP C . n 
C 1 379 ALA 379 439 439 ALA ALA C . n 
C 1 380 HIS 380 440 440 HIS HIS C . n 
C 1 381 GLU 381 441 441 GLU GLU C . n 
C 1 382 HIS 382 442 442 HIS HIS C . n 
C 1 383 GLU 383 443 443 GLU GLU C . n 
C 1 384 PRO 384 444 444 PRO PRO C . n 
C 1 385 LEU 385 445 445 LEU LEU C . n 
C 1 386 LYS 386 446 446 LYS LYS C . n 
C 1 387 THR 387 447 447 THR THR C . n 
C 1 388 LEU 388 448 448 LEU LEU C . n 
C 1 389 TYR 389 449 449 TYR TYR C . n 
C 1 390 ASP 390 450 450 ASP ASP C . n 
C 1 391 ALA 391 451 451 ALA ALA C . n 
C 1 392 VAL 392 452 452 VAL VAL C . n 
C 1 393 GLN 393 453 453 GLN GLN C . n 
C 1 394 SER 394 454 454 SER SER C . n 
C 1 395 ILE 395 455 455 ILE ILE C . n 
C 1 396 LYS 396 456 456 LYS LYS C . n 
C 1 397 PRO 397 457 457 PRO PRO C . n 
C 1 398 THR 398 458 458 THR THR C . n 
C 1 399 VAL 399 459 459 VAL VAL C . n 
C 1 400 LEU 400 460 460 LEU LEU C . n 
C 1 401 ILE 401 461 461 ILE ILE C . n 
C 1 402 GLY 402 462 462 GLY GLY C . n 
C 1 403 THR 403 463 463 THR THR C . n 
C 1 404 SER 404 464 464 SER SER C . n 
C 1 405 GLY 405 465 465 GLY GLY C . n 
C 1 406 VAL 406 466 466 VAL VAL C . n 
C 1 407 GLY 407 467 467 GLY GLY C . n 
C 1 408 ARG 408 468 468 ARG ARG C . n 
C 1 409 THR 409 469 469 THR THR C . n 
C 1 410 PHE 410 470 470 PHE PHE C . n 
C 1 411 THR 411 471 471 THR THR C . n 
C 1 412 LYS 412 472 472 LYS LYS C . n 
C 1 413 GLU 413 473 473 GLU GLU C . n 
C 1 414 ILE 414 474 474 ILE ILE C . n 
C 1 415 ILE 415 475 475 ILE ILE C . n 
C 1 416 GLU 416 476 476 GLU GLU C . n 
C 1 417 ALA 417 477 477 ALA ALA C . n 
C 1 418 MET 418 478 478 MET MET C . n 
C 1 419 SER 419 479 479 SER SER C . n 
C 1 420 SER 420 480 480 SER SER C . n 
C 1 421 PHE 421 481 481 PHE PHE C . n 
C 1 422 ASN 422 482 482 ASN ASN C . n 
C 1 423 GLU 423 483 483 GLU GLU C . n 
C 1 424 ARG 424 484 484 ARG ARG C . n 
C 1 425 PRO 425 485 485 PRO PRO C . n 
C 1 426 ILE 426 486 486 ILE ILE C . n 
C 1 427 ILE 427 487 487 ILE ILE C . n 
C 1 428 PHE 428 488 488 PHE PHE C . n 
C 1 429 SER 429 489 489 SER SER C . n 
C 1 430 LEU 430 490 490 LEU LEU C . n 
C 1 431 SER 431 491 491 SER SER C . n 
C 1 432 ASN 432 492 492 ASN ASN C . n 
C 1 433 PRO 433 493 493 PRO PRO C . n 
C 1 434 THR 434 494 494 THR THR C . n 
C 1 435 SER 435 495 495 SER SER C . n 
C 1 436 HIS 436 496 496 HIS HIS C . n 
C 1 437 SER 437 497 497 SER SER C . n 
C 1 438 GLU 438 498 498 GLU GLU C . n 
C 1 439 CYS 439 499 499 CYS CYS C . n 
C 1 440 THR 440 500 500 THR THR C . n 
C 1 441 ALA 441 501 501 ALA ALA C . n 
C 1 442 GLU 442 502 502 GLU GLU C . n 
C 1 443 GLN 443 503 503 GLN GLN C . n 
C 1 444 ALA 444 504 504 ALA ALA C . n 
C 1 445 TYR 445 505 505 TYR TYR C . n 
C 1 446 THR 446 506 506 THR THR C . n 
C 1 447 TRP 447 507 507 TRP TRP C . n 
C 1 448 SER 448 508 508 SER SER C . n 
C 1 449 GLN 449 509 509 GLN GLN C . n 
C 1 450 GLY 450 510 510 GLY GLY C . n 
C 1 451 ARG 451 511 511 ARG ARG C . n 
C 1 452 SER 452 512 512 SER SER C . n 
C 1 453 ILE 453 513 513 ILE ILE C . n 
C 1 454 PHE 454 514 514 PHE PHE C . n 
C 1 455 ALA 455 515 515 ALA ALA C . n 
C 1 456 SER 456 516 516 SER SER C . n 
C 1 457 GLY 457 517 517 GLY GLY C . n 
C 1 458 SER 458 518 518 SER SER C . n 
C 1 459 PRO 459 519 519 PRO PRO C . n 
C 1 460 PHE 460 520 520 PHE PHE C . n 
C 1 461 ALA 461 521 521 ALA ALA C . n 
C 1 462 PRO 462 522 522 PRO PRO C . n 
C 1 463 VAL 463 523 523 VAL VAL C . n 
C 1 464 GLU 464 524 524 GLU GLU C . n 
C 1 465 TYR 465 525 525 TYR TYR C . n 
C 1 466 GLU 466 526 526 GLU GLU C . n 
C 1 467 GLY 467 527 527 GLY GLY C . n 
C 1 468 LYS 468 528 528 LYS LYS C . n 
C 1 469 THR 469 529 529 THR THR C . n 
C 1 470 PHE 470 530 530 PHE PHE C . n 
C 1 471 VAL 471 531 531 VAL VAL C . n 
C 1 472 PRO 472 532 532 PRO PRO C . n 
C 1 473 GLY 473 533 533 GLY GLY C . n 
C 1 474 GLN 474 534 534 GLN GLN C . n 
C 1 475 SER 475 535 535 SER SER C . n 
C 1 476 ASN 476 536 536 ASN ASN C . n 
C 1 477 ASN 477 537 537 ASN ASN C . n 
C 1 478 ALA 478 538 538 ALA ALA C . n 
C 1 479 TYR 479 539 539 TYR TYR C . n 
C 1 480 ILE 480 540 540 ILE ILE C . n 
C 1 481 PHE 481 541 541 PHE PHE C . n 
C 1 482 PRO 482 542 542 PRO PRO C . n 
C 1 483 GLY 483 543 543 GLY GLY C . n 
C 1 484 LEU 484 544 544 LEU LEU C . n 
C 1 485 GLY 485 545 545 GLY GLY C . n 
C 1 486 LEU 486 546 546 LEU LEU C . n 
C 1 487 GLY 487 547 547 GLY GLY C . n 
C 1 488 LEU 488 548 548 LEU LEU C . n 
C 1 489 VAL 489 549 549 VAL VAL C . n 
C 1 490 ILE 490 550 550 ILE ILE C . n 
C 1 491 SER 491 551 551 SER SER C . n 
C 1 492 GLY 492 552 552 GLY GLY C . n 
C 1 493 ALA 493 553 553 ALA ALA C . n 
C 1 494 VAL 494 554 554 VAL VAL C . n 
C 1 495 ARG 495 555 555 ARG ARG C . n 
C 1 496 VAL 496 556 556 VAL VAL C . n 
C 1 497 HIS 497 557 557 HIS HIS C . n 
C 1 498 GLU 498 558 558 GLU GLU C . n 
C 1 499 ASP 499 559 559 ASP ASP C . n 
C 1 500 MET 500 560 560 MET MET C . n 
C 1 501 LEU 501 561 561 LEU LEU C . n 
C 1 502 LEU 502 562 562 LEU LEU C . n 
C 1 503 ALA 503 563 563 ALA ALA C . n 
C 1 504 ALA 504 564 564 ALA ALA C . n 
C 1 505 SER 505 565 565 SER SER C . n 
C 1 506 LYS 506 566 566 LYS LYS C . n 
C 1 507 ALA 507 567 567 ALA ALA C . n 
C 1 508 LEU 508 568 568 LEU LEU C . n 
C 1 509 ALA 509 569 569 ALA ALA C . n 
C 1 510 ASP 510 570 570 ASP ASP C . n 
C 1 511 GLN 511 571 571 GLN GLN C . n 
C 1 512 ALA 512 572 572 ALA ALA C . n 
C 1 513 THR 513 573 573 THR THR C . n 
C 1 514 GLN 514 574 574 GLN GLN C . n 
C 1 515 ASP 515 575 575 ASP ASP C . n 
C 1 516 ASN 516 576 576 ASN ASN C . n 
C 1 517 PHE 517 577 577 PHE PHE C . n 
C 1 518 GLU 518 578 578 GLU GLU C . n 
C 1 519 LYS 519 579 579 LYS LYS C . n 
C 1 520 GLY 520 580 580 GLY GLY C . n 
C 1 521 SER 521 581 581 SER SER C . n 
C 1 522 ILE 522 582 582 ILE ILE C . n 
C 1 523 PHE 523 583 583 PHE PHE C . n 
C 1 524 PRO 524 584 584 PRO PRO C . n 
C 1 525 PRO 525 585 585 PRO PRO C . n 
C 1 526 PHE 526 586 586 PHE PHE C . n 
C 1 527 THR 527 587 587 THR THR C . n 
C 1 528 SER 528 588 588 SER SER C . n 
C 1 529 ILE 529 589 589 ILE ILE C . n 
C 1 530 ARG 530 590 590 ARG ARG C . n 
C 1 531 LYS 531 591 591 LYS LYS C . n 
C 1 532 ILE 532 592 592 ILE ILE C . n 
C 1 533 SER 533 593 593 SER SER C . n 
C 1 534 ALA 534 594 594 ALA ALA C . n 
C 1 535 HIS 535 595 595 HIS HIS C . n 
C 1 536 ILE 536 596 596 ILE ILE C . n 
C 1 537 ALA 537 597 597 ALA ALA C . n 
C 1 538 ALA 538 598 598 ALA ALA C . n 
C 1 539 ALA 539 599 599 ALA ALA C . n 
C 1 540 VAL 540 600 600 VAL VAL C . n 
C 1 541 ALA 541 601 601 ALA ALA C . n 
C 1 542 ALA 542 602 602 ALA ALA C . n 
C 1 543 LYS 543 603 603 LYS LYS C . n 
C 1 544 ALA 544 604 604 ALA ALA C . n 
C 1 545 TYR 545 605 605 TYR TYR C . n 
C 1 546 GLU 546 606 606 GLU GLU C . n 
C 1 547 LEU 547 607 607 LEU LEU C . n 
C 1 548 GLY 548 608 608 GLY GLY C . n 
C 1 549 LEU 549 609 609 LEU LEU C . n 
C 1 550 ALA 550 610 610 ALA ALA C . n 
C 1 551 THR 551 611 611 THR THR C . n 
C 1 552 ARG 552 612 612 ARG ARG C . n 
C 1 553 LEU 553 613 613 LEU LEU C . n 
C 1 554 PRO 554 614 614 PRO PRO C . n 
C 1 555 PRO 555 615 615 PRO PRO C . n 
C 1 556 PRO 556 616 616 PRO PRO C . n 
C 1 557 SER 557 617 617 SER SER C . n 
C 1 558 ASP 558 618 618 ASP ASP C . n 
C 1 559 LEU 559 619 619 LEU LEU C . n 
C 1 560 VAL 560 620 620 VAL VAL C . n 
C 1 561 LYS 561 621 621 LYS LYS C . n 
C 1 562 TYR 562 622 622 TYR TYR C . n 
C 1 563 ALA 563 623 623 ALA ALA C . n 
C 1 564 GLU 564 624 624 GLU GLU C . n 
C 1 565 ASN 565 625 625 ASN ASN C . n 
C 1 566 CYS 566 626 626 CYS CYS C . n 
C 1 567 MET 567 627 627 MET MET C . n 
C 1 568 TYR 568 628 628 TYR TYR C . n 
C 1 569 THR 569 629 629 THR THR C . n 
C 1 570 PRO 570 630 630 PRO PRO C . n 
C 1 571 VAL 571 631 631 VAL VAL C . n 
C 1 572 TYR 572 632 632 TYR TYR C . n 
C 1 573 ARG 573 633 633 ARG ARG C . n 
C 1 574 ASN 574 634 634 ASN ASN C . n 
C 1 575 TYR 575 635 635 TYR TYR C . n 
C 1 576 ARG 576 636 636 ARG ARG C . n 
D 1 1   HIS 1   61  ?   ?   ?   D . n 
D 1 2   ALA 2   62  ?   ?   ?   D . n 
D 1 3   MET 3   63  ?   ?   ?   D . n 
D 1 4   VAL 4   64  ?   ?   ?   D . n 
D 1 5   SER 5   65  ?   ?   ?   D . n 
D 1 6   ASN 6   66  ?   ?   ?   D . n 
D 1 7   ALA 7   67  ?   ?   ?   D . n 
D 1 8   GLU 8   68  ?   ?   ?   D . n 
D 1 9   THR 9   69  ?   ?   ?   D . n 
D 1 10  GLU 10  70  ?   ?   ?   D . n 
D 1 11  THR 11  71  ?   ?   ?   D . n 
D 1 12  GLU 12  72  72  GLU GLU D . n 
D 1 13  LYS 13  73  73  LYS LYS D . n 
D 1 14  GLU 14  74  74  GLU GLU D . n 
D 1 15  GLN 15  75  75  GLN GLN D . n 
D 1 16  GLU 16  76  76  GLU GLU D . n 
D 1 17  GLU 17  77  77  GLU GLU D . n 
D 1 18  ALA 18  78  78  ALA ALA D . n 
D 1 19  ALA 19  79  79  ALA ALA D . n 
D 1 20  ALA 20  80  80  ALA ALA D . n 
D 1 21  ALA 21  81  81  ALA ALA D . n 
D 1 22  SER 22  82  82  SER SER D . n 
D 1 23  GLU 23  83  83  GLU GLU D . n 
D 1 24  GLU 24  84  84  GLU GLU D . n 
D 1 25  LEU 25  85  85  LEU LEU D . n 
D 1 26  PRO 26  86  86  PRO PRO D . n 
D 1 27  VAL 27  87  87  VAL VAL D . n 
D 1 28  MET 28  88  88  MET MET D . n 
D 1 29  PRO 29  89  89  PRO PRO D . n 
D 1 30  TRP 30  90  90  TRP TRP D . n 
D 1 31  ALA 31  91  91  ALA ALA D . n 
D 1 32  THR 32  92  92  THR THR D . n 
D 1 33  SER 33  93  93  SER SER D . n 
D 1 34  VAL 34  94  94  VAL VAL D . n 
D 1 35  ALA 35  95  95  ALA ALA D . n 
D 1 36  SER 36  96  96  SER SER D . n 
D 1 37  GLY 37  97  97  GLY GLY D . n 
D 1 38  TYR 38  98  98  TYR TYR D . n 
D 1 39  THR 39  99  99  THR THR D . n 
D 1 40  LEU 40  100 100 LEU LEU D . n 
D 1 41  LEU 41  101 101 LEU LEU D . n 
D 1 42  ARG 42  102 102 ARG ARG D . n 
D 1 43  ASP 43  103 103 ASP ASP D . n 
D 1 44  PRO 44  104 104 PRO PRO D . n 
D 1 45  HIS 45  105 105 HIS HIS D . n 
D 1 46  HIS 46  106 106 HIS HIS D . n 
D 1 47  ASN 47  107 107 ASN ASN D . n 
D 1 48  LYS 48  108 108 LYS LYS D . n 
D 1 49  GLY 49  109 109 GLY GLY D . n 
D 1 50  LEU 50  110 110 LEU LEU D . n 
D 1 51  ALA 51  111 111 ALA ALA D . n 
D 1 52  PHE 52  112 112 PHE PHE D . n 
D 1 53  THR 53  113 113 THR THR D . n 
D 1 54  GLU 54  114 114 GLU GLU D . n 
D 1 55  GLU 55  115 115 GLU GLU D . n 
D 1 56  GLU 56  116 116 GLU GLU D . n 
D 1 57  ARG 57  117 117 ARG ARG D . n 
D 1 58  ASP 58  118 118 ASP ASP D . n 
D 1 59  GLY 59  119 119 GLY GLY D . n 
D 1 60  HIS 60  120 120 HIS HIS D . n 
D 1 61  TYR 61  121 121 TYR TYR D . n 
D 1 62  LEU 62  122 122 LEU LEU D . n 
D 1 63  ARG 63  123 123 ARG ARG D . n 
D 1 64  GLY 64  124 124 GLY GLY D . n 
D 1 65  LEU 65  125 125 LEU LEU D . n 
D 1 66  LEU 66  126 126 LEU LEU D . n 
D 1 67  PRO 67  127 127 PRO PRO D . n 
D 1 68  PRO 68  128 128 PRO PRO D . n 
D 1 69  ALA 69  129 129 ALA ALA D . n 
D 1 70  VAL 70  130 130 VAL VAL D . n 
D 1 71  LEU 71  131 131 LEU LEU D . n 
D 1 72  SER 72  132 132 SER SER D . n 
D 1 73  GLN 73  133 133 GLN GLN D . n 
D 1 74  GLU 74  134 134 GLU GLU D . n 
D 1 75  LEU 75  135 135 LEU LEU D . n 
D 1 76  GLN 76  136 136 GLN GLN D . n 
D 1 77  ILE 77  137 137 ILE ILE D . n 
D 1 78  LYS 78  138 138 LYS LYS D . n 
D 1 79  LYS 79  139 139 LYS LYS D . n 
D 1 80  PHE 80  140 140 PHE PHE D . n 
D 1 81  MET 81  141 141 MET MET D . n 
D 1 82  ASN 82  142 142 ASN ASN D . n 
D 1 83  THR 83  143 143 THR THR D . n 
D 1 84  LEU 84  144 144 LEU LEU D . n 
D 1 85  ARG 85  145 145 ARG ARG D . n 
D 1 86  GLN 86  146 146 GLN GLN D . n 
D 1 87  TYR 87  147 147 TYR TYR D . n 
D 1 88  GLN 88  148 148 GLN GLN D . n 
D 1 89  THR 89  149 149 THR THR D . n 
D 1 90  PRO 90  150 150 PRO PRO D . n 
D 1 91  LEU 91  151 151 LEU LEU D . n 
D 1 92  GLN 92  152 152 GLN GLN D . n 
D 1 93  ARG 93  153 153 ARG ARG D . n 
D 1 94  TYR 94  154 154 TYR TYR D . n 
D 1 95  ILE 95  155 155 ILE ILE D . n 
D 1 96  ALA 96  156 156 ALA ALA D . n 
D 1 97  MET 97  157 157 MET MET D . n 
D 1 98  MET 98  158 158 MET MET D . n 
D 1 99  ASN 99  159 159 ASN ASN D . n 
D 1 100 LEU 100 160 160 LEU LEU D . n 
D 1 101 GLN 101 161 161 GLN GLN D . n 
D 1 102 GLU 102 162 162 GLU GLU D . n 
D 1 103 THR 103 163 163 THR THR D . n 
D 1 104 ASP 104 164 164 ASP ASP D . n 
D 1 105 GLU 105 165 165 GLU GLU D . n 
D 1 106 ARG 106 166 166 ARG ARG D . n 
D 1 107 LEU 107 167 167 LEU LEU D . n 
D 1 108 PHE 108 168 168 PHE PHE D . n 
D 1 109 TYR 109 169 169 TYR TYR D . n 
D 1 110 LYS 110 170 170 LYS LYS D . n 
D 1 111 LEU 111 171 171 LEU LEU D . n 
D 1 112 LEU 112 172 172 LEU LEU D . n 
D 1 113 ILE 113 173 173 ILE ILE D . n 
D 1 114 ASP 114 174 174 ASP ASP D . n 
D 1 115 ASN 115 175 175 ASN ASN D . n 
D 1 116 VAL 116 176 176 VAL VAL D . n 
D 1 117 VAL 117 177 177 VAL VAL D . n 
D 1 118 GLU 118 178 178 GLU GLU D . n 
D 1 119 LEU 119 179 179 LEU LEU D . n 
D 1 120 LEU 120 180 180 LEU LEU D . n 
D 1 121 PRO 121 181 181 PRO PRO D . n 
D 1 122 PHE 122 182 182 PHE PHE D . n 
D 1 123 VAL 123 183 183 VAL VAL D . n 
D 1 124 TYR 124 184 184 TYR TYR D . n 
D 1 125 THR 125 185 185 THR THR D . n 
D 1 126 PRO 126 186 186 PRO PRO D . n 
D 1 127 THR 127 187 187 THR THR D . n 
D 1 128 VAL 128 188 188 VAL VAL D . n 
D 1 129 GLY 129 189 189 GLY GLY D . n 
D 1 130 GLU 130 190 190 GLU GLU D . n 
D 1 131 ALA 131 191 191 ALA ALA D . n 
D 1 132 CYS 132 192 192 CYS CYS D . n 
D 1 133 GLN 133 193 193 GLN GLN D . n 
D 1 134 LYS 134 194 194 LYS LYS D . n 
D 1 135 TYR 135 195 195 TYR TYR D . n 
D 1 136 GLY 136 196 196 GLY GLY D . n 
D 1 137 SER 137 197 197 SER SER D . n 
D 1 138 ILE 138 198 198 ILE ILE D . n 
D 1 139 PHE 139 199 199 PHE PHE D . n 
D 1 140 ARG 140 200 200 ARG ARG D . n 
D 1 141 ARG 141 201 201 ARG ARG D . n 
D 1 142 PRO 142 202 202 PRO PRO D . n 
D 1 143 GLN 143 203 203 GLN GLN D . n 
D 1 144 GLY 144 204 204 GLY GLY D . n 
D 1 145 LEU 145 205 205 LEU LEU D . n 
D 1 146 TYR 146 206 206 TYR TYR D . n 
D 1 147 VAL 147 207 207 VAL VAL D . n 
D 1 148 SER 148 208 208 SER SER D . n 
D 1 149 LEU 149 209 209 LEU LEU D . n 
D 1 150 LYS 150 210 210 LYS LYS D . n 
D 1 151 ASP 151 211 211 ASP ASP D . n 
D 1 152 LYS 152 212 212 LYS LYS D . n 
D 1 153 GLY 153 213 213 GLY GLY D . n 
D 1 154 LYS 154 214 214 LYS LYS D . n 
D 1 155 VAL 155 215 215 VAL VAL D . n 
D 1 156 LEU 156 216 216 LEU LEU D . n 
D 1 157 GLU 157 217 217 GLU GLU D . n 
D 1 158 VAL 158 218 218 VAL VAL D . n 
D 1 159 LEU 159 219 219 LEU LEU D . n 
D 1 160 ARG 160 220 220 ARG ARG D . n 
D 1 161 ASN 161 221 221 ASN ASN D . n 
D 1 162 TRP 162 222 222 TRP TRP D . n 
D 1 163 PRO 163 223 223 PRO PRO D . n 
D 1 164 HIS 164 224 224 HIS HIS D . n 
D 1 165 ARG 165 225 225 ARG ARG D . n 
D 1 166 ASN 166 226 226 ASN ASN D . n 
D 1 167 ILE 167 227 227 ILE ILE D . n 
D 1 168 GLN 168 228 228 GLN GLN D . n 
D 1 169 VAL 169 229 229 VAL VAL D . n 
D 1 170 ILE 170 230 230 ILE ILE D . n 
D 1 171 CYS 171 231 231 CYS CYS D . n 
D 1 172 VAL 172 232 232 VAL VAL D . n 
D 1 173 THR 173 233 233 THR THR D . n 
D 1 174 ASP 174 234 234 ASP ASP D . n 
D 1 175 GLY 175 235 235 GLY GLY D . n 
D 1 176 GLU 176 236 236 GLU GLU D . n 
D 1 177 ARG 177 237 237 ARG ARG D . n 
D 1 178 ILE 178 238 238 ILE ILE D . n 
D 1 179 LEU 179 239 239 LEU LEU D . n 
D 1 180 GLY 180 240 240 GLY GLY D . n 
D 1 181 LEU 181 241 241 LEU LEU D . n 
D 1 182 GLY 182 242 242 GLY GLY D . n 
D 1 183 ASP 183 243 243 ASP ASP D . n 
D 1 184 LEU 184 244 244 LEU LEU D . n 
D 1 185 GLY 185 245 245 GLY GLY D . n 
D 1 186 CYS 186 246 246 CYS CYS D . n 
D 1 187 GLN 187 247 247 GLN GLN D . n 
D 1 188 GLY 188 248 248 GLY GLY D . n 
D 1 189 MET 189 249 249 MET MET D . n 
D 1 190 GLY 190 250 250 GLY GLY D . n 
D 1 191 ILE 191 251 251 ILE ILE D . n 
D 1 192 PRO 192 252 252 PRO PRO D . n 
D 1 193 VAL 193 253 253 VAL VAL D . n 
D 1 194 GLY 194 254 254 GLY GLY D . n 
D 1 195 LYS 195 255 255 LYS LYS D . n 
D 1 196 LEU 196 256 256 LEU LEU D . n 
D 1 197 ALA 197 257 257 ALA ALA D . n 
D 1 198 LEU 198 258 258 LEU LEU D . n 
D 1 199 TYR 199 259 259 TYR TYR D . n 
D 1 200 THR 200 260 260 THR THR D . n 
D 1 201 ALA 201 261 261 ALA ALA D . n 
D 1 202 LEU 202 262 262 LEU LEU D . n 
D 1 203 GLY 203 263 263 GLY GLY D . n 
D 1 204 GLY 204 264 264 GLY GLY D . n 
D 1 205 VAL 205 265 265 VAL VAL D . n 
D 1 206 ASP 206 266 266 ASP ASP D . n 
D 1 207 PRO 207 267 267 PRO PRO D . n 
D 1 208 SER 208 268 268 SER SER D . n 
D 1 209 VAL 209 269 269 VAL VAL D . n 
D 1 210 CYS 210 270 270 CYS CYS D . n 
D 1 211 LEU 211 271 271 LEU LEU D . n 
D 1 212 PRO 212 272 272 PRO PRO D . n 
D 1 213 ILE 213 273 273 ILE ILE D . n 
D 1 214 THR 214 274 274 THR THR D . n 
D 1 215 ILE 215 275 275 ILE ILE D . n 
D 1 216 ASP 216 276 276 ASP ASP D . n 
D 1 217 VAL 217 277 277 VAL VAL D . n 
D 1 218 GLY 218 278 278 GLY GLY D . n 
D 1 219 THR 219 279 279 THR THR D . n 
D 1 220 ASN 220 280 280 ASN ASN D . n 
D 1 221 ASN 221 281 281 ASN ASN D . n 
D 1 222 GLU 222 282 282 GLU GLU D . n 
D 1 223 LYS 223 283 283 LYS LYS D . n 
D 1 224 LEU 224 284 284 LEU LEU D . n 
D 1 225 LEU 225 285 285 LEU LEU D . n 
D 1 226 ASN 226 286 286 ASN ASN D . n 
D 1 227 ASP 227 287 287 ASP ASP D . n 
D 1 228 GLU 228 288 288 GLU GLU D . n 
D 1 229 PHE 229 289 289 PHE PHE D . n 
D 1 230 TYR 230 290 290 TYR TYR D . n 
D 1 231 ILE 231 291 291 ILE ILE D . n 
D 1 232 GLY 232 292 292 GLY GLY D . n 
D 1 233 LEU 233 293 293 LEU LEU D . n 
D 1 234 ARG 234 294 294 ARG ARG D . n 
D 1 235 GLN 235 295 295 GLN GLN D . n 
D 1 236 LYS 236 296 296 LYS LYS D . n 
D 1 237 ARG 237 297 297 ARG ARG D . n 
D 1 238 ALA 238 298 298 ALA ALA D . n 
D 1 239 THR 239 299 299 THR THR D . n 
D 1 240 GLY 240 300 300 GLY GLY D . n 
D 1 241 GLU 241 301 301 GLU GLU D . n 
D 1 242 GLU 242 302 302 GLU GLU D . n 
D 1 243 TYR 243 303 303 TYR TYR D . n 
D 1 244 ASP 244 304 304 ASP ASP D . n 
D 1 245 GLU 245 305 305 GLU GLU D . n 
D 1 246 LEU 246 306 306 LEU LEU D . n 
D 1 247 ILE 247 307 307 ILE ILE D . n 
D 1 248 GLU 248 308 308 GLU GLU D . n 
D 1 249 GLU 249 309 309 GLU GLU D . n 
D 1 250 PHE 250 310 310 PHE PHE D . n 
D 1 251 MET 251 311 311 MET MET D . n 
D 1 252 SER 252 312 312 SER SER D . n 
D 1 253 ALA 253 313 313 ALA ALA D . n 
D 1 254 VAL 254 314 314 VAL VAL D . n 
D 1 255 LYS 255 315 315 LYS LYS D . n 
D 1 256 GLN 256 316 316 GLN GLN D . n 
D 1 257 PHE 257 317 317 PHE PHE D . n 
D 1 258 TYR 258 318 318 TYR TYR D . n 
D 1 259 GLY 259 319 319 GLY GLY D . n 
D 1 260 GLU 260 320 320 GLU GLU D . n 
D 1 261 LYS 261 321 321 LYS LYS D . n 
D 1 262 VAL 262 322 322 VAL VAL D . n 
D 1 263 LEU 263 323 323 LEU LEU D . n 
D 1 264 ILE 264 324 324 ILE ILE D . n 
D 1 265 GLN 265 325 325 GLN GLN D . n 
D 1 266 PHE 266 326 326 PHE PHE D . n 
D 1 267 GLU 267 327 327 GLU GLU D . n 
D 1 268 ASP 268 328 328 ASP ASP D . n 
D 1 269 PHE 269 329 329 PHE PHE D . n 
D 1 270 ALA 270 330 330 ALA ALA D . n 
D 1 271 ASN 271 331 331 ASN ASN D . n 
D 1 272 HIS 272 332 332 HIS HIS D . n 
D 1 273 ASN 273 333 333 ASN ASN D . n 
D 1 274 ALA 274 334 334 ALA ALA D . n 
D 1 275 PHE 275 335 335 PHE PHE D . n 
D 1 276 ASP 276 336 336 ASP ASP D . n 
D 1 277 LEU 277 337 337 LEU LEU D . n 
D 1 278 LEU 278 338 338 LEU LEU D . n 
D 1 279 GLU 279 339 339 GLU GLU D . n 
D 1 280 LYS 280 340 340 LYS LYS D . n 
D 1 281 TYR 281 341 341 TYR TYR D . n 
D 1 282 SER 282 342 342 SER SER D . n 
D 1 283 LYS 283 343 343 LYS LYS D . n 
D 1 284 SER 284 344 344 SER SER D . n 
D 1 285 HIS 285 345 345 HIS HIS D . n 
D 1 286 LEU 286 346 346 LEU LEU D . n 
D 1 287 VAL 287 347 347 VAL VAL D . n 
D 1 288 PHE 288 348 348 PHE PHE D . n 
D 1 289 ASN 289 349 349 ASN ASN D . n 
D 1 290 ASP 290 350 350 ASP ASP D . n 
D 1 291 ASP 291 351 351 ASP ASP D . n 
D 1 292 ILE 292 352 352 ILE ILE D . n 
D 1 293 GLN 293 353 353 GLN GLN D . n 
D 1 294 GLY 294 354 354 GLY GLY D . n 
D 1 295 THR 295 355 355 THR THR D . n 
D 1 296 ALA 296 356 356 ALA ALA D . n 
D 1 297 SER 297 357 357 SER SER D . n 
D 1 298 VAL 298 358 358 VAL VAL D . n 
D 1 299 VAL 299 359 359 VAL VAL D . n 
D 1 300 LEU 300 360 360 LEU LEU D . n 
D 1 301 ALA 301 361 361 ALA ALA D . n 
D 1 302 GLY 302 362 362 GLY GLY D . n 
D 1 303 LEU 303 363 363 LEU LEU D . n 
D 1 304 LEU 304 364 364 LEU LEU D . n 
D 1 305 ALA 305 365 365 ALA ALA D . n 
D 1 306 ALA 306 366 366 ALA ALA D . n 
D 1 307 LEU 307 367 367 LEU LEU D . n 
D 1 308 LYS 308 368 368 LYS LYS D . n 
D 1 309 MET 309 369 369 MET MET D . n 
D 1 310 VAL 310 370 370 VAL VAL D . n 
D 1 311 GLY 311 371 371 GLY GLY D . n 
D 1 312 GLY 312 372 372 GLY GLY D . n 
D 1 313 THR 313 373 373 THR THR D . n 
D 1 314 LEU 314 374 374 LEU LEU D . n 
D 1 315 ALA 315 375 375 ALA ALA D . n 
D 1 316 GLU 316 376 376 GLU GLU D . n 
D 1 317 GLN 317 377 377 GLN GLN D . n 
D 1 318 THR 318 378 378 THR THR D . n 
D 1 319 TYR 319 379 379 TYR TYR D . n 
D 1 320 LEU 320 380 380 LEU LEU D . n 
D 1 321 PHE 321 381 381 PHE PHE D . n 
D 1 322 LEU 322 382 382 LEU LEU D . n 
D 1 323 GLY 323 383 383 GLY GLY D . n 
D 1 324 ALA 324 384 384 ALA ALA D . n 
D 1 325 GLY 325 385 385 GLY GLY D . n 
D 1 326 GLU 326 386 386 GLU GLU D . n 
D 1 327 ALA 327 387 387 ALA ALA D . n 
D 1 328 GLY 328 388 388 GLY GLY D . n 
D 1 329 THR 329 389 389 THR THR D . n 
D 1 330 GLY 330 390 390 GLY GLY D . n 
D 1 331 ILE 331 391 391 ILE ILE D . n 
D 1 332 ALA 332 392 392 ALA ALA D . n 
D 1 333 GLU 333 393 393 GLU GLU D . n 
D 1 334 LEU 334 394 394 LEU LEU D . n 
D 1 335 ILE 335 395 395 ILE ILE D . n 
D 1 336 ALA 336 396 396 ALA ALA D . n 
D 1 337 LEU 337 397 397 LEU LEU D . n 
D 1 338 GLU 338 398 398 GLU GLU D . n 
D 1 339 ILE 339 399 399 ILE ILE D . n 
D 1 340 SER 340 400 400 SER SER D . n 
D 1 341 LYS 341 401 401 LYS LYS D . n 
D 1 342 GLN 342 402 402 GLN GLN D . n 
D 1 343 THR 343 403 403 THR THR D . n 
D 1 344 ASN 344 404 404 ASN ASN D . n 
D 1 345 ALA 345 405 405 ALA ALA D . n 
D 1 346 PRO 346 406 406 PRO PRO D . n 
D 1 347 ILE 347 407 407 ILE ILE D . n 
D 1 348 GLU 348 408 408 GLU GLU D . n 
D 1 349 GLU 349 409 409 GLU GLU D . n 
D 1 350 CYS 350 410 410 CYS CYS D . n 
D 1 351 ARG 351 411 411 ARG ARG D . n 
D 1 352 LYS 352 412 412 LYS LYS D . n 
D 1 353 LYS 353 413 413 LYS LYS D . n 
D 1 354 VAL 354 414 414 VAL VAL D . n 
D 1 355 TRP 355 415 415 TRP TRP D . n 
D 1 356 LEU 356 416 416 LEU LEU D . n 
D 1 357 VAL 357 417 417 VAL VAL D . n 
D 1 358 ASP 358 418 418 ASP ASP D . n 
D 1 359 SER 359 419 419 SER SER D . n 
D 1 360 LYS 360 420 420 LYS LYS D . n 
D 1 361 GLY 361 421 421 GLY GLY D . n 
D 1 362 LEU 362 422 422 LEU LEU D . n 
D 1 363 ILE 363 423 423 ILE ILE D . n 
D 1 364 VAL 364 424 424 VAL VAL D . n 
D 1 365 ASP 365 425 425 ASP ASP D . n 
D 1 366 SER 366 426 426 SER SER D . n 
D 1 367 ARG 367 427 427 ARG ARG D . n 
D 1 368 LYS 368 428 428 LYS LYS D . n 
D 1 369 GLY 369 429 429 GLY GLY D . n 
D 1 370 SER 370 430 430 SER SER D . n 
D 1 371 LEU 371 431 431 LEU LEU D . n 
D 1 372 GLN 372 432 432 GLN GLN D . n 
D 1 373 PRO 373 433 433 PRO PRO D . n 
D 1 374 PHE 374 434 434 PHE PHE D . n 
D 1 375 LYS 375 435 435 LYS LYS D . n 
D 1 376 LYS 376 436 436 LYS LYS D . n 
D 1 377 PRO 377 437 437 PRO PRO D . n 
D 1 378 TRP 378 438 438 TRP TRP D . n 
D 1 379 ALA 379 439 439 ALA ALA D . n 
D 1 380 HIS 380 440 440 HIS HIS D . n 
D 1 381 GLU 381 441 441 GLU GLU D . n 
D 1 382 HIS 382 442 442 HIS HIS D . n 
D 1 383 GLU 383 443 443 GLU GLU D . n 
D 1 384 PRO 384 444 444 PRO PRO D . n 
D 1 385 LEU 385 445 445 LEU LEU D . n 
D 1 386 LYS 386 446 446 LYS LYS D . n 
D 1 387 THR 387 447 447 THR THR D . n 
D 1 388 LEU 388 448 448 LEU LEU D . n 
D 1 389 TYR 389 449 449 TYR TYR D . n 
D 1 390 ASP 390 450 450 ASP ASP D . n 
D 1 391 ALA 391 451 451 ALA ALA D . n 
D 1 392 VAL 392 452 452 VAL VAL D . n 
D 1 393 GLN 393 453 453 GLN GLN D . n 
D 1 394 SER 394 454 454 SER SER D . n 
D 1 395 ILE 395 455 455 ILE ILE D . n 
D 1 396 LYS 396 456 456 LYS LYS D . n 
D 1 397 PRO 397 457 457 PRO PRO D . n 
D 1 398 THR 398 458 458 THR THR D . n 
D 1 399 VAL 399 459 459 VAL VAL D . n 
D 1 400 LEU 400 460 460 LEU LEU D . n 
D 1 401 ILE 401 461 461 ILE ILE D . n 
D 1 402 GLY 402 462 462 GLY GLY D . n 
D 1 403 THR 403 463 463 THR THR D . n 
D 1 404 SER 404 464 464 SER SER D . n 
D 1 405 GLY 405 465 465 GLY GLY D . n 
D 1 406 VAL 406 466 466 VAL VAL D . n 
D 1 407 GLY 407 467 467 GLY GLY D . n 
D 1 408 ARG 408 468 468 ARG ARG D . n 
D 1 409 THR 409 469 469 THR THR D . n 
D 1 410 PHE 410 470 470 PHE PHE D . n 
D 1 411 THR 411 471 471 THR THR D . n 
D 1 412 LYS 412 472 472 LYS LYS D . n 
D 1 413 GLU 413 473 473 GLU GLU D . n 
D 1 414 ILE 414 474 474 ILE ILE D . n 
D 1 415 ILE 415 475 475 ILE ILE D . n 
D 1 416 GLU 416 476 476 GLU GLU D . n 
D 1 417 ALA 417 477 477 ALA ALA D . n 
D 1 418 MET 418 478 478 MET MET D . n 
D 1 419 SER 419 479 479 SER SER D . n 
D 1 420 SER 420 480 480 SER SER D . n 
D 1 421 PHE 421 481 481 PHE PHE D . n 
D 1 422 ASN 422 482 482 ASN ASN D . n 
D 1 423 GLU 423 483 483 GLU GLU D . n 
D 1 424 ARG 424 484 484 ARG ARG D . n 
D 1 425 PRO 425 485 485 PRO PRO D . n 
D 1 426 ILE 426 486 486 ILE ILE D . n 
D 1 427 ILE 427 487 487 ILE ILE D . n 
D 1 428 PHE 428 488 488 PHE PHE D . n 
D 1 429 SER 429 489 489 SER SER D . n 
D 1 430 LEU 430 490 490 LEU LEU D . n 
D 1 431 SER 431 491 491 SER SER D . n 
D 1 432 ASN 432 492 492 ASN ASN D . n 
D 1 433 PRO 433 493 493 PRO PRO D . n 
D 1 434 THR 434 494 494 THR THR D . n 
D 1 435 SER 435 495 495 SER SER D . n 
D 1 436 HIS 436 496 496 HIS HIS D . n 
D 1 437 SER 437 497 497 SER SER D . n 
D 1 438 GLU 438 498 498 GLU GLU D . n 
D 1 439 CYS 439 499 499 CYS CYS D . n 
D 1 440 THR 440 500 500 THR THR D . n 
D 1 441 ALA 441 501 501 ALA ALA D . n 
D 1 442 GLU 442 502 502 GLU GLU D . n 
D 1 443 GLN 443 503 503 GLN GLN D . n 
D 1 444 ALA 444 504 504 ALA ALA D . n 
D 1 445 TYR 445 505 505 TYR TYR D . n 
D 1 446 THR 446 506 506 THR THR D . n 
D 1 447 TRP 447 507 507 TRP TRP D . n 
D 1 448 SER 448 508 508 SER SER D . n 
D 1 449 GLN 449 509 509 GLN GLN D . n 
D 1 450 GLY 450 510 510 GLY GLY D . n 
D 1 451 ARG 451 511 511 ARG ARG D . n 
D 1 452 SER 452 512 512 SER SER D . n 
D 1 453 ILE 453 513 513 ILE ILE D . n 
D 1 454 PHE 454 514 514 PHE PHE D . n 
D 1 455 ALA 455 515 515 ALA ALA D . n 
D 1 456 SER 456 516 516 SER SER D . n 
D 1 457 GLY 457 517 517 GLY GLY D . n 
D 1 458 SER 458 518 518 SER SER D . n 
D 1 459 PRO 459 519 519 PRO PRO D . n 
D 1 460 PHE 460 520 520 PHE PHE D . n 
D 1 461 ALA 461 521 521 ALA ALA D . n 
D 1 462 PRO 462 522 522 PRO PRO D . n 
D 1 463 VAL 463 523 523 VAL VAL D . n 
D 1 464 GLU 464 524 524 GLU GLU D . n 
D 1 465 TYR 465 525 525 TYR TYR D . n 
D 1 466 GLU 466 526 526 GLU GLU D . n 
D 1 467 GLY 467 527 527 GLY GLY D . n 
D 1 468 LYS 468 528 528 LYS LYS D . n 
D 1 469 THR 469 529 529 THR THR D . n 
D 1 470 PHE 470 530 530 PHE PHE D . n 
D 1 471 VAL 471 531 531 VAL VAL D . n 
D 1 472 PRO 472 532 532 PRO PRO D . n 
D 1 473 GLY 473 533 533 GLY GLY D . n 
D 1 474 GLN 474 534 534 GLN GLN D . n 
D 1 475 SER 475 535 535 SER SER D . n 
D 1 476 ASN 476 536 536 ASN ASN D . n 
D 1 477 ASN 477 537 537 ASN ASN D . n 
D 1 478 ALA 478 538 538 ALA ALA D . n 
D 1 479 TYR 479 539 539 TYR TYR D . n 
D 1 480 ILE 480 540 540 ILE ILE D . n 
D 1 481 PHE 481 541 541 PHE PHE D . n 
D 1 482 PRO 482 542 542 PRO PRO D . n 
D 1 483 GLY 483 543 543 GLY GLY D . n 
D 1 484 LEU 484 544 544 LEU LEU D . n 
D 1 485 GLY 485 545 545 GLY GLY D . n 
D 1 486 LEU 486 546 546 LEU LEU D . n 
D 1 487 GLY 487 547 547 GLY GLY D . n 
D 1 488 LEU 488 548 548 LEU LEU D . n 
D 1 489 VAL 489 549 549 VAL VAL D . n 
D 1 490 ILE 490 550 550 ILE ILE D . n 
D 1 491 SER 491 551 551 SER SER D . n 
D 1 492 GLY 492 552 552 GLY GLY D . n 
D 1 493 ALA 493 553 553 ALA ALA D . n 
D 1 494 VAL 494 554 554 VAL VAL D . n 
D 1 495 ARG 495 555 555 ARG ARG D . n 
D 1 496 VAL 496 556 556 VAL VAL D . n 
D 1 497 HIS 497 557 557 HIS HIS D . n 
D 1 498 GLU 498 558 558 GLU GLU D . n 
D 1 499 ASP 499 559 559 ASP ASP D . n 
D 1 500 MET 500 560 560 MET MET D . n 
D 1 501 LEU 501 561 561 LEU LEU D . n 
D 1 502 LEU 502 562 562 LEU LEU D . n 
D 1 503 ALA 503 563 563 ALA ALA D . n 
D 1 504 ALA 504 564 564 ALA ALA D . n 
D 1 505 SER 505 565 565 SER SER D . n 
D 1 506 LYS 506 566 566 LYS LYS D . n 
D 1 507 ALA 507 567 567 ALA ALA D . n 
D 1 508 LEU 508 568 568 LEU LEU D . n 
D 1 509 ALA 509 569 569 ALA ALA D . n 
D 1 510 ASP 510 570 570 ASP ASP D . n 
D 1 511 GLN 511 571 571 GLN GLN D . n 
D 1 512 ALA 512 572 572 ALA ALA D . n 
D 1 513 THR 513 573 573 THR THR D . n 
D 1 514 GLN 514 574 574 GLN GLN D . n 
D 1 515 ASP 515 575 575 ASP ASP D . n 
D 1 516 ASN 516 576 576 ASN ASN D . n 
D 1 517 PHE 517 577 577 PHE PHE D . n 
D 1 518 GLU 518 578 578 GLU GLU D . n 
D 1 519 LYS 519 579 579 LYS LYS D . n 
D 1 520 GLY 520 580 580 GLY GLY D . n 
D 1 521 SER 521 581 581 SER SER D . n 
D 1 522 ILE 522 582 582 ILE ILE D . n 
D 1 523 PHE 523 583 583 PHE PHE D . n 
D 1 524 PRO 524 584 584 PRO PRO D . n 
D 1 525 PRO 525 585 585 PRO PRO D . n 
D 1 526 PHE 526 586 586 PHE PHE D . n 
D 1 527 THR 527 587 587 THR THR D . n 
D 1 528 SER 528 588 588 SER SER D . n 
D 1 529 ILE 529 589 589 ILE ILE D . n 
D 1 530 ARG 530 590 590 ARG ARG D . n 
D 1 531 LYS 531 591 591 LYS LYS D . n 
D 1 532 ILE 532 592 592 ILE ILE D . n 
D 1 533 SER 533 593 593 SER SER D . n 
D 1 534 ALA 534 594 594 ALA ALA D . n 
D 1 535 HIS 535 595 595 HIS HIS D . n 
D 1 536 ILE 536 596 596 ILE ILE D . n 
D 1 537 ALA 537 597 597 ALA ALA D . n 
D 1 538 ALA 538 598 598 ALA ALA D . n 
D 1 539 ALA 539 599 599 ALA ALA D . n 
D 1 540 VAL 540 600 600 VAL VAL D . n 
D 1 541 ALA 541 601 601 ALA ALA D . n 
D 1 542 ALA 542 602 602 ALA ALA D . n 
D 1 543 LYS 543 603 603 LYS LYS D . n 
D 1 544 ALA 544 604 604 ALA ALA D . n 
D 1 545 TYR 545 605 605 TYR TYR D . n 
D 1 546 GLU 546 606 606 GLU GLU D . n 
D 1 547 LEU 547 607 607 LEU LEU D . n 
D 1 548 GLY 548 608 608 GLY GLY D . n 
D 1 549 LEU 549 609 609 LEU LEU D . n 
D 1 550 ALA 550 610 610 ALA ALA D . n 
D 1 551 THR 551 611 611 THR THR D . n 
D 1 552 ARG 552 612 612 ARG ARG D . n 
D 1 553 LEU 553 613 613 LEU LEU D . n 
D 1 554 PRO 554 614 614 PRO PRO D . n 
D 1 555 PRO 555 615 615 PRO PRO D . n 
D 1 556 PRO 556 616 616 PRO PRO D . n 
D 1 557 SER 557 617 617 SER SER D . n 
D 1 558 ASP 558 618 618 ASP ASP D . n 
D 1 559 LEU 559 619 619 LEU LEU D . n 
D 1 560 VAL 560 620 620 VAL VAL D . n 
D 1 561 LYS 561 621 621 LYS LYS D . n 
D 1 562 TYR 562 622 622 TYR TYR D . n 
D 1 563 ALA 563 623 623 ALA ALA D . n 
D 1 564 GLU 564 624 624 GLU GLU D . n 
D 1 565 ASN 565 625 625 ASN ASN D . n 
D 1 566 CYS 566 626 626 CYS CYS D . n 
D 1 567 MET 567 627 627 MET MET D . n 
D 1 568 TYR 568 628 628 TYR TYR D . n 
D 1 569 THR 569 629 629 THR THR D . n 
D 1 570 PRO 570 630 630 PRO PRO D . n 
D 1 571 VAL 571 631 631 VAL VAL D . n 
D 1 572 TYR 572 632 632 TYR TYR D . n 
D 1 573 ARG 573 633 633 ARG ARG D . n 
D 1 574 ASN 574 634 634 ASN ASN D . n 
D 1 575 TYR 575 635 635 TYR TYR D . n 
D 1 576 ARG 576 636 636 ARG ARG D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        PYR 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   PYR 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 PYR 1  701 1  PYR PYR A . 
F 2 PYR 1  702 2  PYR PYR A . 
G 2 PYR 1  701 3  PYR PYR B . 
H 2 PYR 1  701 4  PYR PYR C . 
I 2 PYR 1  702 5  PYR PYR C . 
J 2 PYR 1  701 6  PYR PYR D . 
K 3 HOH 1  801 6  HOH HOH A . 
K 3 HOH 2  802 1  HOH HOH A . 
K 3 HOH 3  803 4  HOH HOH A . 
K 3 HOH 4  804 49 HOH HOH A . 
K 3 HOH 5  805 2  HOH HOH A . 
K 3 HOH 6  806 52 HOH HOH A . 
K 3 HOH 7  807 5  HOH HOH A . 
K 3 HOH 8  808 8  HOH HOH A . 
L 3 HOH 1  801 17 HOH HOH B . 
L 3 HOH 2  802 22 HOH HOH B . 
L 3 HOH 3  803 11 HOH HOH B . 
L 3 HOH 4  804 19 HOH HOH B . 
M 3 HOH 1  801 31 HOH HOH C . 
M 3 HOH 2  802 28 HOH HOH C . 
M 3 HOH 3  803 27 HOH HOH C . 
M 3 HOH 4  804 51 HOH HOH C . 
M 3 HOH 5  805 25 HOH HOH C . 
M 3 HOH 6  806 33 HOH HOH C . 
M 3 HOH 7  807 29 HOH HOH C . 
N 3 HOH 1  801 45 HOH HOH D . 
N 3 HOH 2  802 50 HOH HOH D . 
N 3 HOH 3  803 37 HOH HOH D . 
N 3 HOH 4  804 39 HOH HOH D . 
N 3 HOH 5  805 44 HOH HOH D . 
N 3 HOH 6  806 35 HOH HOH D . 
N 3 HOH 7  807 30 HOH HOH D . 
N 3 HOH 8  808 41 HOH HOH D . 
N 3 HOH 9  809 42 HOH HOH D . 
N 3 HOH 10 810 40 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0258 1 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? MxCuBE  ? ? ? .        2 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        4 
? phasing           ? ? ? ? ? ? ? ? ? ? ? MrBUMP  ? ? ? .        5 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9E6M 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     98.679 
_cell.length_a_esd                 ? 
_cell.length_b                     124.161 
_cell.length_b_esd                 ? 
_cell.length_c                     189.472 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9E6M 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9E6M 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.28 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.96 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              4.6 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.0 M ammonium sulfate, 0.1 M sodium acetate/acetic acid buffer, pH 4.6' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-06-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    Oxford-FMB 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97623 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97623 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P13 (MX1)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          50 
_reflns.entry_id                                       9E6M 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.7 
_reflns.d_resolution_low                               124.16 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     63889 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.1 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.213 
_reflns.pdbx_Rpim_I_all                                0.092 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.993 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.190 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.70 
_reflns_shell.d_res_low                                     2.77 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.1 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4473 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               5.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.865 
_reflns_shell.pdbx_Rpim_I_all                               0.78 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.62 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.8 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.687 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -6.49 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            -0.00 
_refine.aniso_B[2][2]                            9.77 
_refine.aniso_B[2][3]                            0.00 
_refine.aniso_B[3][3]                            -3.27 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               61.416 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.947 
_refine.correlation_coeff_Fo_to_Fc_free          0.915 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9E6M 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.70 
_refine.ls_d_res_low                             50.01 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     60592 
_refine.ls_number_reflns_R_free                  3227 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.74 
_refine.ls_percent_reflns_R_free                 5.1 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.24182 
_refine.ls_R_factor_R_free                       0.29617 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.23895 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  0.439 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             26.425 
_refine.overall_SU_ML                            0.480 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.70 
_refine_hist.d_res_low                        50.01 
_refine_hist.number_atoms_solvent             29 
_refine_hist.number_atoms_total               17498 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        17433 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         36 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.013  17851 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.017  16718 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.707  1.643  24206 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 1.253  1.569  38851 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.981  5.000  2231  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 34.281 22.761 873   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 20.407 15.000 3044  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? 21.383 15.000 92    ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.077  0.200  2311  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  19933 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.020  3627  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 6.330  6.272  8936  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 6.330  6.271  8935  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 9.279  9.409  11163 ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 9.278  9.410  11164 ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 7.119  6.896  8915  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 7.119  6.896  8916  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 10.743 10.089 13044 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 13.761 73.636 19478 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 13.761 73.638 19479 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.12 ? 0.05 1  'interatomic distance' ? A 16965 ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.12 ? 0.05 2  'interatomic distance' ? B 16965 ? ? 1 
'X-RAY DIFFRACTION' 1 ? ? 0.11 ? 0.05 3  'interatomic distance' ? A 17222 ? ? 2 
'X-RAY DIFFRACTION' 2 ? ? 0.11 ? 0.05 4  'interatomic distance' ? C 17222 ? ? 2 
'X-RAY DIFFRACTION' 1 ? ? 0.11 ? 0.05 5  'interatomic distance' ? A 17606 ? ? 3 
'X-RAY DIFFRACTION' 2 ? ? 0.11 ? 0.05 6  'interatomic distance' ? D 17606 ? ? 3 
'X-RAY DIFFRACTION' 1 ? ? 0.11 ? 0.05 7  'interatomic distance' ? B 17176 ? ? 4 
'X-RAY DIFFRACTION' 2 ? ? 0.11 ? 0.05 8  'interatomic distance' ? C 17176 ? ? 4 
'X-RAY DIFFRACTION' 1 ? ? 0.12 ? 0.05 9  'interatomic distance' ? B 17035 ? ? 5 
'X-RAY DIFFRACTION' 2 ? ? 0.12 ? 0.05 10 'interatomic distance' ? D 17035 ? ? 5 
'X-RAY DIFFRACTION' 1 ? ? 0.11 ? 0.05 11 'interatomic distance' ? C 17177 ? ? 6 
'X-RAY DIFFRACTION' 2 ? ? 0.11 ? 0.05 12 'interatomic distance' ? D 17177 ? ? 6 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.700 
_refine_ls_shell.d_res_low                        2.770 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             286 
_refine_ls_shell.number_reflns_R_work             4371 
_refine_ls_shell.percent_reflns_obs               99.72 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.421 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.432 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.details 
_struct_ncs_dom.pdbx_ens_id 
1 ? 1 
2 ? 2 
3 ? 3 
4 ? 4 
5 ? 5 
6 ? 6 
# 
loop_
_struct_ncs_ens.id 
_struct_ncs_ens.details 
1 ? 
2 ? 
3 ? 
4 ? 
5 ? 
6 ? 
# 
_struct.entry_id                     9E6M 
_struct.title                        
'Crystal structure of the G200R mutant from the maize chloroplastic photosynthetic NADP(+)-dependent malic enzyme' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9E6M 
_struct_keywords.text            'malic enzyme, oxidative decarboxylase, NADP-dependent C4 photosynthesis, PHOTOSYNTHESIS' 
_struct_keywords.pdbx_keywords   PHOTOSYNTHESIS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 2 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    B4F8P6_MAIZE 
_struct_ref.pdbx_db_accession          B4F8P6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;AMVSNAETETEKEQEEAAAASEELPVMPWATSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKFM
NTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKDKGKVLEVLRN
WPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITIDVGTNNEKLLNDEFYIGLRQKRATGE
EYDELIEEFMSAVKQFYGEKVLIQFEDFANHNAFDLLEKYSKSHLVFNDDIQGTASVVLAGLLAALKMVGGTLAEQTYLF
LGAGEAGTGIAELIALEISKQTNAPIEECRKKVWLVDSKGLIVDSRKGSLQPFKKPWAHEHEPLKTLYDAVQSIKPTVLI
GTSGVGRTFTKEIIEAMSSFNERPIIFSLSNPTSHSECTAEQAYTWSQGRSIFASGSPFAPVEYEGKTFVPGQSNNAYIF
PGLGLGLVISGAVRVHEDMLLAASKALADQATQDNFEKGSIFPPFTSIRKISAHIAAAVAAKAYELGLATRLPPPSDLVK
YAENCMYTPVYRNYR
;
_struct_ref.pdbx_align_begin           62 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9E6M A 2 ? 576 ? B4F8P6 62 ? 636 ? 62 636 
2 1 9E6M B 2 ? 576 ? B4F8P6 62 ? 636 ? 62 636 
3 1 9E6M C 2 ? 576 ? B4F8P6 62 ? 636 ? 62 636 
4 1 9E6M D 2 ? 576 ? B4F8P6 62 ? 636 ? 62 636 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9E6M HIS A 1   ? UNP B4F8P6 ?   ?   'expression tag'      61  1 
1 9E6M ARG A 140 ? UNP B4F8P6 GLY 200 'engineered mutation' 200 2 
2 9E6M HIS B 1   ? UNP B4F8P6 ?   ?   'expression tag'      61  3 
2 9E6M ARG B 140 ? UNP B4F8P6 GLY 200 'engineered mutation' 200 4 
3 9E6M HIS C 1   ? UNP B4F8P6 ?   ?   'expression tag'      61  5 
3 9E6M ARG C 140 ? UNP B4F8P6 GLY 200 'engineered mutation' 200 6 
4 9E6M HIS D 1   ? UNP B4F8P6 ?   ?   'expression tag'      61  7 
4 9E6M ARG D 140 ? UNP B4F8P6 GLY 200 'engineered mutation' 200 8 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 19370 ? 
1 MORE         -72   ? 
1 'SSA (A^2)'  76820 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1   AA1 SER A 36  ? ARG A 42  ? SER A 96  ARG A 102 1 ? 7  
HELX_P HELX_P2   AA2 LYS A 48  ? PHE A 52  ? LYS A 108 PHE A 112 5 ? 5  
HELX_P HELX_P3   AA3 THR A 53  ? HIS A 60  ? THR A 113 HIS A 120 1 ? 8  
HELX_P HELX_P4   AA4 SER A 72  ? ARG A 85  ? SER A 132 ARG A 145 1 ? 14 
HELX_P HELX_P5   AA5 THR A 89  ? GLU A 102 ? THR A 149 GLU A 162 1 ? 14 
HELX_P HELX_P6   AA6 ASP A 104 ? ASN A 115 ? ASP A 164 ASN A 175 1 ? 12 
HELX_P HELX_P7   AA7 ASN A 115 ? TYR A 124 ? ASN A 175 TYR A 184 1 ? 10 
HELX_P HELX_P8   AA8 PRO A 126 ? LYS A 134 ? PRO A 186 LYS A 194 1 ? 9  
HELX_P HELX_P9   AA9 TYR A 135 ? ILE A 138 ? TYR A 195 ILE A 198 5 ? 4  
HELX_P HELX_P10  AB1 LYS A 150 ? LYS A 152 ? LYS A 210 LYS A 212 5 ? 3  
HELX_P HELX_P11  AB2 LYS A 154 ? ASN A 161 ? LYS A 214 ASN A 221 1 ? 8  
HELX_P HELX_P12  AB3 LEU A 184 ? GLY A 188 ? LEU A 244 GLY A 248 5 ? 5  
HELX_P HELX_P13  AB4 MET A 189 ? LEU A 202 ? MET A 249 LEU A 262 1 ? 14 
HELX_P HELX_P14  AB5 ASP A 206 ? SER A 208 ? ASP A 266 SER A 268 5 ? 3  
HELX_P HELX_P15  AB6 ASN A 221 ? ASP A 227 ? ASN A 281 ASP A 287 1 ? 7  
HELX_P HELX_P16  AB7 THR A 239 ? GLY A 259 ? THR A 299 GLY A 319 1 ? 21 
HELX_P HELX_P17  AB8 ALA A 270 ? TYR A 281 ? ALA A 330 TYR A 341 1 ? 12 
HELX_P HELX_P18  AB9 ILE A 292 ? GLY A 311 ? ILE A 352 GLY A 371 1 ? 20 
HELX_P HELX_P19  AC1 GLY A 325 ? ASN A 344 ? GLY A 385 ASN A 404 1 ? 20 
HELX_P HELX_P20  AC2 PRO A 346 ? ARG A 351 ? PRO A 406 ARG A 411 1 ? 6  
HELX_P HELX_P21  AC3 VAL A 364 ? LEU A 371 ? VAL A 424 LEU A 431 5 ? 8  
HELX_P HELX_P22  AC4 GLN A 372 ? ALA A 379 ? GLN A 432 ALA A 439 5 ? 8  
HELX_P HELX_P23  AC5 THR A 387 ? LYS A 396 ? THR A 447 LYS A 456 1 ? 10 
HELX_P HELX_P24  AC6 THR A 411 ? ASN A 422 ? THR A 471 ASN A 482 1 ? 12 
HELX_P HELX_P25  AC7 PRO A 433 ? SER A 437 ? PRO A 493 SER A 497 5 ? 5  
HELX_P HELX_P26  AC8 THR A 440 ? TRP A 447 ? THR A 500 TRP A 507 1 ? 8  
HELX_P HELX_P27  AC9 ASN A 476 ? TYR A 479 ? ASN A 536 TYR A 539 5 ? 4  
HELX_P HELX_P28  AD1 ILE A 480 ? GLY A 492 ? ILE A 540 GLY A 552 1 ? 13 
HELX_P HELX_P29  AD2 HIS A 497 ? ASP A 510 ? HIS A 557 ASP A 570 1 ? 14 
HELX_P HELX_P30  AD3 THR A 513 ? LYS A 519 ? THR A 573 LYS A 579 1 ? 7  
HELX_P HELX_P31  AD4 PRO A 525 ? THR A 527 ? PRO A 585 THR A 587 5 ? 3  
HELX_P HELX_P32  AD5 SER A 528 ? LEU A 547 ? SER A 588 LEU A 607 1 ? 20 
HELX_P HELX_P33  AD6 ASP A 558 ? CYS A 566 ? ASP A 618 CYS A 626 1 ? 9  
HELX_P HELX_P34  AD7 SER B 36  ? ASP B 43  ? SER B 96  ASP B 103 1 ? 8  
HELX_P HELX_P35  AD8 LYS B 48  ? PHE B 52  ? LYS B 108 PHE B 112 5 ? 5  
HELX_P HELX_P36  AD9 THR B 53  ? HIS B 60  ? THR B 113 HIS B 120 1 ? 8  
HELX_P HELX_P37  AE1 SER B 72  ? ARG B 85  ? SER B 132 ARG B 145 1 ? 14 
HELX_P HELX_P38  AE2 THR B 89  ? GLU B 102 ? THR B 149 GLU B 162 1 ? 14 
HELX_P HELX_P39  AE3 ASP B 104 ? ASN B 115 ? ASP B 164 ASN B 175 1 ? 12 
HELX_P HELX_P40  AE4 ASN B 115 ? TYR B 124 ? ASN B 175 TYR B 184 1 ? 10 
HELX_P HELX_P41  AE5 PRO B 126 ? LYS B 134 ? PRO B 186 LYS B 194 1 ? 9  
HELX_P HELX_P42  AE6 TYR B 135 ? ILE B 138 ? TYR B 195 ILE B 198 5 ? 4  
HELX_P HELX_P43  AE7 LYS B 150 ? LYS B 152 ? LYS B 210 LYS B 212 5 ? 3  
HELX_P HELX_P44  AE8 LYS B 154 ? ASN B 161 ? LYS B 214 ASN B 221 1 ? 8  
HELX_P HELX_P45  AE9 LEU B 184 ? GLY B 188 ? LEU B 244 GLY B 248 5 ? 5  
HELX_P HELX_P46  AF1 MET B 189 ? LEU B 202 ? MET B 249 LEU B 262 1 ? 14 
HELX_P HELX_P47  AF2 ASP B 206 ? SER B 208 ? ASP B 266 SER B 268 5 ? 3  
HELX_P HELX_P48  AF3 ASN B 221 ? ASP B 227 ? ASN B 281 ASP B 287 1 ? 7  
HELX_P HELX_P49  AF4 THR B 239 ? GLY B 259 ? THR B 299 GLY B 319 1 ? 21 
HELX_P HELX_P50  AF5 ALA B 270 ? TYR B 281 ? ALA B 330 TYR B 341 1 ? 12 
HELX_P HELX_P51  AF6 ILE B 292 ? GLY B 311 ? ILE B 352 GLY B 371 1 ? 20 
HELX_P HELX_P52  AF7 GLY B 325 ? ASN B 344 ? GLY B 385 ASN B 404 1 ? 20 
HELX_P HELX_P53  AF8 PRO B 346 ? ARG B 351 ? PRO B 406 ARG B 411 1 ? 6  
HELX_P HELX_P54  AF9 VAL B 364 ? LEU B 371 ? VAL B 424 LEU B 431 5 ? 8  
HELX_P HELX_P55  AG1 GLN B 372 ? ALA B 379 ? GLN B 432 ALA B 439 5 ? 8  
HELX_P HELX_P56  AG2 THR B 387 ? LYS B 396 ? THR B 447 LYS B 456 1 ? 10 
HELX_P HELX_P57  AG3 THR B 411 ? ASN B 422 ? THR B 471 ASN B 482 1 ? 12 
HELX_P HELX_P58  AG4 PRO B 433 ? SER B 437 ? PRO B 493 SER B 497 5 ? 5  
HELX_P HELX_P59  AG5 THR B 440 ? TRP B 447 ? THR B 500 TRP B 507 1 ? 8  
HELX_P HELX_P60  AG6 ASN B 476 ? TYR B 479 ? ASN B 536 TYR B 539 5 ? 4  
HELX_P HELX_P61  AG7 ILE B 480 ? GLY B 492 ? ILE B 540 GLY B 552 1 ? 13 
HELX_P HELX_P62  AG8 HIS B 497 ? ASP B 510 ? HIS B 557 ASP B 570 1 ? 14 
HELX_P HELX_P63  AG9 THR B 513 ? LYS B 519 ? THR B 573 LYS B 579 1 ? 7  
HELX_P HELX_P64  AH1 PRO B 525 ? THR B 527 ? PRO B 585 THR B 587 5 ? 3  
HELX_P HELX_P65  AH2 SER B 528 ? LEU B 547 ? SER B 588 LEU B 607 1 ? 20 
HELX_P HELX_P66  AH3 ASP B 558 ? CYS B 566 ? ASP B 618 CYS B 626 1 ? 9  
HELX_P HELX_P67  AH4 SER C 36  ? ARG C 42  ? SER C 96  ARG C 102 1 ? 7  
HELX_P HELX_P68  AH5 LYS C 48  ? PHE C 52  ? LYS C 108 PHE C 112 5 ? 5  
HELX_P HELX_P69  AH6 THR C 53  ? HIS C 60  ? THR C 113 HIS C 120 1 ? 8  
HELX_P HELX_P70  AH7 SER C 72  ? ARG C 85  ? SER C 132 ARG C 145 1 ? 14 
HELX_P HELX_P71  AH8 THR C 89  ? GLU C 102 ? THR C 149 GLU C 162 1 ? 14 
HELX_P HELX_P72  AH9 ASP C 104 ? ASN C 115 ? ASP C 164 ASN C 175 1 ? 12 
HELX_P HELX_P73  AI1 ASN C 115 ? TYR C 124 ? ASN C 175 TYR C 184 1 ? 10 
HELX_P HELX_P74  AI2 PRO C 126 ? LYS C 134 ? PRO C 186 LYS C 194 1 ? 9  
HELX_P HELX_P75  AI3 TYR C 135 ? ILE C 138 ? TYR C 195 ILE C 198 5 ? 4  
HELX_P HELX_P76  AI4 LYS C 150 ? LYS C 152 ? LYS C 210 LYS C 212 5 ? 3  
HELX_P HELX_P77  AI5 LYS C 154 ? ASN C 161 ? LYS C 214 ASN C 221 1 ? 8  
HELX_P HELX_P78  AI6 LEU C 184 ? GLY C 188 ? LEU C 244 GLY C 248 5 ? 5  
HELX_P HELX_P79  AI7 MET C 189 ? LEU C 202 ? MET C 249 LEU C 262 1 ? 14 
HELX_P HELX_P80  AI8 ASP C 206 ? SER C 208 ? ASP C 266 SER C 268 5 ? 3  
HELX_P HELX_P81  AI9 ASN C 221 ? ASN C 226 ? ASN C 281 ASN C 286 1 ? 6  
HELX_P HELX_P82  AJ1 THR C 239 ? GLY C 259 ? THR C 299 GLY C 319 1 ? 21 
HELX_P HELX_P83  AJ2 ALA C 270 ? HIS C 285 ? ALA C 330 HIS C 345 1 ? 16 
HELX_P HELX_P84  AJ3 ILE C 292 ? GLY C 311 ? ILE C 352 GLY C 371 1 ? 20 
HELX_P HELX_P85  AJ4 GLY C 325 ? ASN C 344 ? GLY C 385 ASN C 404 1 ? 20 
HELX_P HELX_P86  AJ5 PRO C 346 ? ARG C 351 ? PRO C 406 ARG C 411 1 ? 6  
HELX_P HELX_P87  AJ6 VAL C 364 ? LEU C 371 ? VAL C 424 LEU C 431 5 ? 8  
HELX_P HELX_P88  AJ7 GLN C 372 ? ALA C 379 ? GLN C 432 ALA C 439 5 ? 8  
HELX_P HELX_P89  AJ8 THR C 387 ? LYS C 396 ? THR C 447 LYS C 456 1 ? 10 
HELX_P HELX_P90  AJ9 THR C 411 ? ASN C 422 ? THR C 471 ASN C 482 1 ? 12 
HELX_P HELX_P91  AK1 PRO C 433 ? SER C 437 ? PRO C 493 SER C 497 5 ? 5  
HELX_P HELX_P92  AK2 THR C 440 ? TRP C 447 ? THR C 500 TRP C 507 1 ? 8  
HELX_P HELX_P93  AK3 ASN C 476 ? TYR C 479 ? ASN C 536 TYR C 539 5 ? 4  
HELX_P HELX_P94  AK4 ILE C 480 ? GLY C 492 ? ILE C 540 GLY C 552 1 ? 13 
HELX_P HELX_P95  AK5 HIS C 497 ? ASP C 510 ? HIS C 557 ASP C 570 1 ? 14 
HELX_P HELX_P96  AK6 THR C 513 ? LYS C 519 ? THR C 573 LYS C 579 1 ? 7  
HELX_P HELX_P97  AK7 PRO C 525 ? THR C 527 ? PRO C 585 THR C 587 5 ? 3  
HELX_P HELX_P98  AK8 SER C 528 ? LEU C 547 ? SER C 588 LEU C 607 1 ? 20 
HELX_P HELX_P99  AK9 ASP C 558 ? CYS C 566 ? ASP C 618 CYS C 626 1 ? 9  
HELX_P HELX_P100 AL1 SER D 36  ? ASP D 43  ? SER D 96  ASP D 103 1 ? 8  
HELX_P HELX_P101 AL2 LYS D 48  ? PHE D 52  ? LYS D 108 PHE D 112 5 ? 5  
HELX_P HELX_P102 AL3 THR D 53  ? HIS D 60  ? THR D 113 HIS D 120 1 ? 8  
HELX_P HELX_P103 AL4 SER D 72  ? ARG D 85  ? SER D 132 ARG D 145 1 ? 14 
HELX_P HELX_P104 AL5 THR D 89  ? GLU D 102 ? THR D 149 GLU D 162 1 ? 14 
HELX_P HELX_P105 AL6 ASP D 104 ? ASN D 115 ? ASP D 164 ASN D 175 1 ? 12 
HELX_P HELX_P106 AL7 ASN D 115 ? TYR D 124 ? ASN D 175 TYR D 184 1 ? 10 
HELX_P HELX_P107 AL8 PRO D 126 ? LYS D 134 ? PRO D 186 LYS D 194 1 ? 9  
HELX_P HELX_P108 AL9 TYR D 135 ? ILE D 138 ? TYR D 195 ILE D 198 5 ? 4  
HELX_P HELX_P109 AM1 LYS D 150 ? LYS D 152 ? LYS D 210 LYS D 212 5 ? 3  
HELX_P HELX_P110 AM2 LYS D 154 ? ASN D 161 ? LYS D 214 ASN D 221 1 ? 8  
HELX_P HELX_P111 AM3 LEU D 184 ? GLY D 188 ? LEU D 244 GLY D 248 5 ? 5  
HELX_P HELX_P112 AM4 MET D 189 ? LEU D 202 ? MET D 249 LEU D 262 1 ? 14 
HELX_P HELX_P113 AM5 ASP D 206 ? SER D 208 ? ASP D 266 SER D 268 5 ? 3  
HELX_P HELX_P114 AM6 ASN D 221 ? ASP D 227 ? ASN D 281 ASP D 287 1 ? 7  
HELX_P HELX_P115 AM7 THR D 239 ? GLY D 259 ? THR D 299 GLY D 319 1 ? 21 
HELX_P HELX_P116 AM8 ALA D 270 ? TYR D 281 ? ALA D 330 TYR D 341 1 ? 12 
HELX_P HELX_P117 AM9 ILE D 292 ? GLY D 311 ? ILE D 352 GLY D 371 1 ? 20 
HELX_P HELX_P118 AN1 GLY D 325 ? ASN D 344 ? GLY D 385 ASN D 404 1 ? 20 
HELX_P HELX_P119 AN2 PRO D 346 ? ARG D 351 ? PRO D 406 ARG D 411 1 ? 6  
HELX_P HELX_P120 AN3 VAL D 364 ? LEU D 371 ? VAL D 424 LEU D 431 5 ? 8  
HELX_P HELX_P121 AN4 GLN D 372 ? ALA D 379 ? GLN D 432 ALA D 439 5 ? 8  
HELX_P HELX_P122 AN5 THR D 387 ? LYS D 396 ? THR D 447 LYS D 456 1 ? 10 
HELX_P HELX_P123 AN6 THR D 411 ? ASN D 422 ? THR D 471 ASN D 482 1 ? 12 
HELX_P HELX_P124 AN7 PRO D 433 ? SER D 437 ? PRO D 493 SER D 497 5 ? 5  
HELX_P HELX_P125 AN8 THR D 440 ? TRP D 447 ? THR D 500 TRP D 507 1 ? 8  
HELX_P HELX_P126 AN9 ASN D 476 ? TYR D 479 ? ASN D 536 TYR D 539 5 ? 4  
HELX_P HELX_P127 AO1 ILE D 480 ? GLY D 492 ? ILE D 540 GLY D 552 1 ? 13 
HELX_P HELX_P128 AO2 HIS D 497 ? ASP D 510 ? HIS D 557 ASP D 570 1 ? 14 
HELX_P HELX_P129 AO3 THR D 513 ? LYS D 519 ? THR D 573 LYS D 579 1 ? 7  
HELX_P HELX_P130 AO4 PRO D 525 ? THR D 527 ? PRO D 585 THR D 587 5 ? 3  
HELX_P HELX_P131 AO5 SER D 528 ? LEU D 547 ? SER D 588 LEU D 607 1 ? 20 
HELX_P HELX_P132 AO6 ASP D 558 ? CYS D 566 ? ASP D 618 CYS D 626 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1  THR 125 A . ? THR 185 A PRO 126 A ? PRO 186 A 1 7.06  
2  ASN 432 A . ? ASN 492 A PRO 433 A ? PRO 493 A 1 -0.49 
3  LEU 553 A . ? LEU 613 A PRO 554 A ? PRO 614 A 1 -9.79 
4  THR 125 B . ? THR 185 B PRO 126 B ? PRO 186 B 1 7.18  
5  ASN 432 B . ? ASN 492 B PRO 433 B ? PRO 493 B 1 -2.23 
6  LEU 553 B . ? LEU 613 B PRO 554 B ? PRO 614 B 1 -6.12 
7  THR 125 C . ? THR 185 C PRO 126 C ? PRO 186 C 1 6.50  
8  ASN 432 C . ? ASN 492 C PRO 433 C ? PRO 493 C 1 -0.89 
9  LEU 553 C . ? LEU 613 C PRO 554 C ? PRO 614 C 1 -5.25 
10 THR 125 D . ? THR 185 D PRO 126 D ? PRO 186 D 1 5.87  
11 ASN 432 D . ? ASN 492 D PRO 433 D ? PRO 493 D 1 -3.12 
12 LEU 553 D . ? LEU 613 D PRO 554 D ? PRO 614 D 1 -5.97 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 5 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 5 ? 
AA8 ? 7 ? 
AA9 ? 2 ? 
AB1 ? 5 ? 
AB2 ? 7 ? 
AB3 ? 2 ? 
AB4 ? 5 ? 
AB5 ? 7 ? 
AB6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? parallel      
AA6 1 2 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA9 1 2 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? parallel      
AB1 3 4 ? parallel      
AB1 4 5 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB2 5 6 ? parallel      
AB2 6 7 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? parallel      
AB4 3 4 ? parallel      
AB4 4 5 ? parallel      
AB5 1 2 ? anti-parallel 
AB5 2 3 ? parallel      
AB5 3 4 ? parallel      
AB5 4 5 ? parallel      
AB5 5 6 ? parallel      
AB5 6 7 ? parallel      
AB6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TRP A 30  ? VAL A 34  ? TRP A 90  VAL A 94  
AA1 2 TRP C 30  ? VAL C 34  ? TRP C 90  VAL C 94  
AA2 1 LEU A 145 ? SER A 148 ? LEU A 205 SER A 208 
AA2 2 CYS A 210 ? ASP A 216 ? CYS A 270 ASP A 276 
AA2 3 VAL A 169 ? THR A 173 ? VAL A 229 THR A 233 
AA2 4 LEU A 263 ? PHE A 266 ? LEU A 323 PHE A 326 
AA2 5 LEU A 286 ? ASN A 289 ? LEU A 346 ASN A 349 
AA3 1 GLY A 361 ? LEU A 362 ? GLY A 421 LEU A 422 
AA3 2 VAL A 354 ? ASP A 358 ? VAL A 414 ASP A 418 
AA3 3 TYR A 319 ? LEU A 322 ? TYR A 379 LEU A 382 
AA3 4 VAL A 399 ? GLY A 402 ? VAL A 459 GLY A 462 
AA3 5 ILE A 426 ? SER A 429 ? ILE A 486 SER A 489 
AA3 6 ILE A 453 ? SER A 456 ? ILE A 513 SER A 516 
AA3 7 GLY A 473 ? GLN A 474 ? GLY A 533 GLN A 534 
AA4 1 VAL A 463 ? TYR A 465 ? VAL A 523 TYR A 525 
AA4 2 LYS A 468 ? PHE A 470 ? LYS A 528 PHE A 530 
AA5 1 PRO B 26  ? VAL B 27  ? PRO B 86  VAL B 87  
AA5 2 ASN D 574 ? TYR D 575 ? ASN D 634 TYR D 635 
AA6 1 TRP B 30  ? VAL B 34  ? TRP B 90  VAL B 94  
AA6 2 TRP D 30  ? VAL D 34  ? TRP D 90  VAL D 94  
AA7 1 LEU B 145 ? SER B 148 ? LEU B 205 SER B 208 
AA7 2 CYS B 210 ? ASP B 216 ? CYS B 270 ASP B 276 
AA7 3 VAL B 169 ? THR B 173 ? VAL B 229 THR B 233 
AA7 4 LEU B 263 ? PHE B 266 ? LEU B 323 PHE B 326 
AA7 5 LEU B 286 ? ASN B 289 ? LEU B 346 ASN B 349 
AA8 1 GLY B 361 ? LEU B 362 ? GLY B 421 LEU B 422 
AA8 2 VAL B 354 ? ASP B 358 ? VAL B 414 ASP B 418 
AA8 3 TYR B 319 ? LEU B 322 ? TYR B 379 LEU B 382 
AA8 4 VAL B 399 ? GLY B 402 ? VAL B 459 GLY B 462 
AA8 5 ILE B 426 ? SER B 429 ? ILE B 486 SER B 489 
AA8 6 ILE B 453 ? SER B 456 ? ILE B 513 SER B 516 
AA8 7 GLY B 473 ? GLN B 474 ? GLY B 533 GLN B 534 
AA9 1 VAL B 463 ? TYR B 465 ? VAL B 523 TYR B 525 
AA9 2 LYS B 468 ? PHE B 470 ? LYS B 528 PHE B 530 
AB1 1 LEU C 145 ? SER C 148 ? LEU C 205 SER C 208 
AB1 2 CYS C 210 ? ASP C 216 ? CYS C 270 ASP C 276 
AB1 3 VAL C 169 ? THR C 173 ? VAL C 229 THR C 233 
AB1 4 LEU C 263 ? PHE C 266 ? LEU C 323 PHE C 326 
AB1 5 LEU C 286 ? ASN C 289 ? LEU C 346 ASN C 349 
AB2 1 GLY C 361 ? LEU C 362 ? GLY C 421 LEU C 422 
AB2 2 VAL C 354 ? ASP C 358 ? VAL C 414 ASP C 418 
AB2 3 TYR C 319 ? LEU C 322 ? TYR C 379 LEU C 382 
AB2 4 VAL C 399 ? GLY C 402 ? VAL C 459 GLY C 462 
AB2 5 ILE C 426 ? SER C 429 ? ILE C 486 SER C 489 
AB2 6 ILE C 453 ? SER C 456 ? ILE C 513 SER C 516 
AB2 7 GLY C 473 ? GLN C 474 ? GLY C 533 GLN C 534 
AB3 1 VAL C 463 ? TYR C 465 ? VAL C 523 TYR C 525 
AB3 2 LYS C 468 ? PHE C 470 ? LYS C 528 PHE C 530 
AB4 1 LEU D 145 ? SER D 148 ? LEU D 205 SER D 208 
AB4 2 CYS D 210 ? ASP D 216 ? CYS D 270 ASP D 276 
AB4 3 VAL D 169 ? THR D 173 ? VAL D 229 THR D 233 
AB4 4 LEU D 263 ? PHE D 266 ? LEU D 323 PHE D 326 
AB4 5 LEU D 286 ? ASN D 289 ? LEU D 346 ASN D 349 
AB5 1 GLY D 361 ? LEU D 362 ? GLY D 421 LEU D 422 
AB5 2 VAL D 354 ? ASP D 358 ? VAL D 414 ASP D 418 
AB5 3 TYR D 319 ? LEU D 322 ? TYR D 379 LEU D 382 
AB5 4 VAL D 399 ? GLY D 402 ? VAL D 459 GLY D 462 
AB5 5 ILE D 426 ? SER D 429 ? ILE D 486 SER D 489 
AB5 6 ILE D 453 ? SER D 456 ? ILE D 513 SER D 516 
AB5 7 GLY D 473 ? GLN D 474 ? GLY D 533 GLN D 534 
AB6 1 VAL D 463 ? TYR D 465 ? VAL D 523 TYR D 525 
AB6 2 LYS D 468 ? PHE D 470 ? LYS D 528 PHE D 530 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 33  ? N SER A 93  O ALA C 31  ? O ALA C 91  
AA2 1 2 N LEU A 145 ? N LEU A 205 O PRO A 212 ? O PRO A 272 
AA2 2 3 O ILE A 213 ? O ILE A 273 N CYS A 171 ? N CYS A 231 
AA2 3 4 N ILE A 170 ? N ILE A 230 O LEU A 263 ? O LEU A 323 
AA2 4 5 N PHE A 266 ? N PHE A 326 O PHE A 288 ? O PHE A 348 
AA3 1 2 O GLY A 361 ? O GLY A 421 N ASP A 358 ? N ASP A 418 
AA3 2 3 O TRP A 355 ? O TRP A 415 N TYR A 319 ? N TYR A 379 
AA3 3 4 N LEU A 320 ? N LEU A 380 O VAL A 399 ? O VAL A 459 
AA3 4 5 N GLY A 402 ? N GLY A 462 O PHE A 428 ? O PHE A 488 
AA3 5 6 N ILE A 427 ? N ILE A 487 O ILE A 453 ? O ILE A 513 
AA3 6 7 N SER A 456 ? N SER A 516 O GLY A 473 ? O GLY A 533 
AA4 1 2 N VAL A 463 ? N VAL A 523 O PHE A 470 ? O PHE A 530 
AA5 1 2 N VAL B 27  ? N VAL B 87  O ASN D 574 ? O ASN D 634 
AA6 1 2 N SER B 33  ? N SER B 93  O ALA D 31  ? O ALA D 91  
AA7 1 2 N LEU B 145 ? N LEU B 205 O PRO B 212 ? O PRO B 272 
AA7 2 3 O ILE B 213 ? O ILE B 273 N CYS B 171 ? N CYS B 231 
AA7 3 4 N ILE B 170 ? N ILE B 230 O LEU B 263 ? O LEU B 323 
AA7 4 5 N PHE B 266 ? N PHE B 326 O PHE B 288 ? O PHE B 348 
AA8 1 2 O GLY B 361 ? O GLY B 421 N ASP B 358 ? N ASP B 418 
AA8 2 3 O TRP B 355 ? O TRP B 415 N TYR B 319 ? N TYR B 379 
AA8 3 4 N LEU B 320 ? N LEU B 380 O VAL B 399 ? O VAL B 459 
AA8 4 5 N GLY B 402 ? N GLY B 462 O PHE B 428 ? O PHE B 488 
AA8 5 6 N SER B 429 ? N SER B 489 O ALA B 455 ? O ALA B 515 
AA8 6 7 N SER B 456 ? N SER B 516 O GLY B 473 ? O GLY B 533 
AA9 1 2 N VAL B 463 ? N VAL B 523 O PHE B 470 ? O PHE B 530 
AB1 1 2 N LEU C 145 ? N LEU C 205 O PRO C 212 ? O PRO C 272 
AB1 2 3 O ILE C 213 ? O ILE C 273 N CYS C 171 ? N CYS C 231 
AB1 3 4 N ILE C 170 ? N ILE C 230 O LEU C 263 ? O LEU C 323 
AB1 4 5 N PHE C 266 ? N PHE C 326 O PHE C 288 ? O PHE C 348 
AB2 1 2 O GLY C 361 ? O GLY C 421 N ASP C 358 ? N ASP C 418 
AB2 2 3 O TRP C 355 ? O TRP C 415 N TYR C 319 ? N TYR C 379 
AB2 3 4 N LEU C 320 ? N LEU C 380 O VAL C 399 ? O VAL C 459 
AB2 4 5 N GLY C 402 ? N GLY C 462 O PHE C 428 ? O PHE C 488 
AB2 5 6 N SER C 429 ? N SER C 489 O ALA C 455 ? O ALA C 515 
AB2 6 7 N SER C 456 ? N SER C 516 O GLY C 473 ? O GLY C 533 
AB3 1 2 N VAL C 463 ? N VAL C 523 O PHE C 470 ? O PHE C 530 
AB4 1 2 N LEU D 145 ? N LEU D 205 O PRO D 212 ? O PRO D 272 
AB4 2 3 O ILE D 213 ? O ILE D 273 N CYS D 171 ? N CYS D 231 
AB4 3 4 N ILE D 170 ? N ILE D 230 O LEU D 263 ? O LEU D 323 
AB4 4 5 N PHE D 266 ? N PHE D 326 O PHE D 288 ? O PHE D 348 
AB5 1 2 O GLY D 361 ? O GLY D 421 N ASP D 358 ? N ASP D 418 
AB5 2 3 O TRP D 355 ? O TRP D 415 N TYR D 319 ? N TYR D 379 
AB5 3 4 N LEU D 320 ? N LEU D 380 O VAL D 399 ? O VAL D 459 
AB5 4 5 N GLY D 402 ? N GLY D 462 O PHE D 428 ? O PHE D 488 
AB5 5 6 N ILE D 427 ? N ILE D 487 O ILE D 453 ? O ILE D 513 
AB5 6 7 N SER D 456 ? N SER D 516 O GLY D 473 ? O GLY D 533 
AB6 1 2 N VAL D 463 ? N VAL D 523 O PHE D 470 ? O PHE D 530 
# 
_pdbx_entry_details.entry_id                   9E6M 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OG1 A THR 373 ? ? OE2 A GLU 376 ? ? 1.63 
2  1 OH  C TYR 259 ? ? OE1 C GLN 325 ? ? 2.03 
3  1 OH  B TYR 259 ? ? OE1 B GLN 325 ? ? 2.04 
4  1 OH  A TYR 259 ? ? OE1 A GLN 325 ? ? 2.04 
5  1 OH  D TYR 259 ? ? OE1 D GLN 325 ? ? 2.05 
6  1 OD1 A ASP 211 ? ? NH1 B ARG 123 ? ? 2.08 
7  1 O   A LEU 338 ? ? OG  A SER 342 ? ? 2.09 
8  1 O   C LEU 338 ? ? OG  C SER 342 ? ? 2.09 
9  1 O   B LEU 338 ? ? OG  B SER 342 ? ? 2.09 
10 1 O   D LEU 338 ? ? OG  D SER 342 ? ? 2.10 
11 1 O   A VAL 531 ? ? OG  A SER 581 ? ? 2.11 
12 1 O   B VAL 531 ? ? OG  B SER 581 ? ? 2.12 
13 1 O   D VAL 531 ? ? OG  D SER 581 ? ? 2.12 
14 1 OE1 D GLU 393 ? ? NH1 D ARG 411 ? ? 2.15 
15 1 OD2 A ASP 266 ? ? OG  A SER 268 ? ? 2.16 
16 1 OD2 D ASP 266 ? ? OG  D SER 268 ? ? 2.17 
17 1 OE1 B GLN 377 ? ? CG2 B THR 458 ? ? 2.18 
18 1 OE1 C GLN 161 ? ? NE2 C GLN 203 ? ? 2.19 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             165 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OE1 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             165 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.329 
_pdbx_validate_rmsd_bond.bond_target_value         1.252 
_pdbx_validate_rmsd_bond.bond_deviation            0.077 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.011 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CB A LYS 343 ? ? CA A LYS 343 ? ? C   A LYS 343 ? ? 122.97 110.40 12.57 2.00 N 
2 1 CB D GLN 148 ? ? CA D GLN 148 ? ? C   D GLN 148 ? ? 123.53 110.40 13.13 2.00 N 
3 1 NE D ARG 468 ? ? CZ D ARG 468 ? ? NH2 D ARG 468 ? ? 123.64 120.30 3.34  0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 80  ? ? -95.46  44.27   
2  1 SER A 82  ? ? -93.48  53.39   
3  1 GLU A 83  ? ? -122.84 -53.59  
4  1 THR A 163 ? ? -138.86 -39.29  
5  1 TYR A 184 ? ? -123.85 -169.08 
6  1 LEU A 239 ? ? 46.79   -140.28 
7  1 ASN A 281 ? ? -49.97  100.38  
8  1 GLU A 301 ? ? -28.77  -65.13  
9  1 ASN A 331 ? ? -41.04  -74.47  
10 1 ALA A 384 ? ? -104.10 57.04   
11 1 ASP A 418 ? ? -100.66 -169.02 
12 1 SER A 430 ? ? -172.64 45.28   
13 1 HIS A 440 ? ? -67.48  -175.71 
14 1 THR A 587 ? ? -60.07  1.39    
15 1 THR B 163 ? ? -138.22 -38.44  
16 1 TYR B 184 ? ? -123.51 -168.75 
17 1 LEU B 239 ? ? 46.25   -140.40 
18 1 ASN B 281 ? ? -53.20  99.06   
19 1 GLU B 301 ? ? -23.85  -69.59  
20 1 LYS B 321 ? ? -65.30  4.10    
21 1 ASN B 331 ? ? -50.40  -70.42  
22 1 ALA B 384 ? ? -106.48 53.42   
23 1 SER B 430 ? ? -170.30 60.59   
24 1 HIS B 440 ? ? -70.23  -164.38 
25 1 HIS B 442 ? ? 176.81  158.55  
26 1 GLU B 558 ? ? -39.80  -38.13  
27 1 THR B 587 ? ? -54.50  -6.08   
28 1 THR C 163 ? ? -138.26 -37.86  
29 1 TYR C 184 ? ? -122.53 -169.15 
30 1 LEU C 239 ? ? 48.11   -141.16 
31 1 ASN C 281 ? ? -52.89  100.57  
32 1 LYS C 321 ? ? -64.62  2.27    
33 1 ALA C 384 ? ? -105.65 56.15   
34 1 GLU C 386 ? ? -54.06  -70.38  
35 1 SER C 430 ? ? -168.69 55.39   
36 1 THR C 587 ? ? -55.23  -4.25   
37 1 LYS D 73  ? ? 78.26   -65.45  
38 1 THR D 163 ? ? -138.85 -39.49  
39 1 TYR D 184 ? ? -123.29 -168.53 
40 1 LEU D 239 ? ? 46.60   -140.52 
41 1 ASN D 281 ? ? -51.68  100.32  
42 1 ALA D 384 ? ? -104.04 55.67   
43 1 GLU D 386 ? ? -48.40  -70.31  
44 1 ASP D 418 ? ? -102.25 -169.46 
45 1 SER D 430 ? ? -169.11 64.85   
46 1 HIS D 440 ? ? -66.01  -174.91 
47 1 GLU D 558 ? ? -38.34  -37.57  
48 1 THR D 587 ? ? -59.60  1.10    
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A HIS 61 ? A HIS 1  
2  1 Y 1 A ALA 62 ? A ALA 2  
3  1 Y 1 A MET 63 ? A MET 3  
4  1 Y 1 A VAL 64 ? A VAL 4  
5  1 Y 1 A SER 65 ? A SER 5  
6  1 Y 1 A ASN 66 ? A ASN 6  
7  1 Y 1 A ALA 67 ? A ALA 7  
8  1 Y 1 A GLU 68 ? A GLU 8  
9  1 Y 1 A THR 69 ? A THR 9  
10 1 Y 1 A GLU 70 ? A GLU 10 
11 1 Y 1 A THR 71 ? A THR 11 
12 1 Y 1 B HIS 61 ? B HIS 1  
13 1 Y 1 B ALA 62 ? B ALA 2  
14 1 Y 1 B MET 63 ? B MET 3  
15 1 Y 1 B VAL 64 ? B VAL 4  
16 1 Y 1 B SER 65 ? B SER 5  
17 1 Y 1 B ASN 66 ? B ASN 6  
18 1 Y 1 B ALA 67 ? B ALA 7  
19 1 Y 1 B GLU 68 ? B GLU 8  
20 1 Y 1 B THR 69 ? B THR 9  
21 1 Y 1 B GLU 70 ? B GLU 10 
22 1 Y 1 B THR 71 ? B THR 11 
23 1 Y 1 B GLU 72 ? B GLU 12 
24 1 Y 1 B LYS 73 ? B LYS 13 
25 1 Y 1 B GLU 74 ? B GLU 14 
26 1 Y 1 B GLN 75 ? B GLN 15 
27 1 Y 1 B GLU 76 ? B GLU 16 
28 1 Y 1 B GLU 77 ? B GLU 17 
29 1 Y 1 B ALA 78 ? B ALA 18 
30 1 Y 1 B ALA 79 ? B ALA 19 
31 1 Y 1 B ALA 80 ? B ALA 20 
32 1 Y 1 B ALA 81 ? B ALA 21 
33 1 Y 1 B SER 82 ? B SER 22 
34 1 Y 1 B GLU 83 ? B GLU 23 
35 1 Y 1 C HIS 61 ? C HIS 1  
36 1 Y 1 C ALA 62 ? C ALA 2  
37 1 Y 1 C MET 63 ? C MET 3  
38 1 Y 1 C VAL 64 ? C VAL 4  
39 1 Y 1 C SER 65 ? C SER 5  
40 1 Y 1 C ASN 66 ? C ASN 6  
41 1 Y 1 C ALA 67 ? C ALA 7  
42 1 Y 1 C GLU 68 ? C GLU 8  
43 1 Y 1 C THR 69 ? C THR 9  
44 1 Y 1 C GLU 70 ? C GLU 10 
45 1 Y 1 C THR 71 ? C THR 11 
46 1 Y 1 C GLU 72 ? C GLU 12 
47 1 Y 1 C LYS 73 ? C LYS 13 
48 1 Y 1 C GLU 74 ? C GLU 14 
49 1 Y 1 C GLN 75 ? C GLN 15 
50 1 Y 1 C GLU 76 ? C GLU 16 
51 1 Y 1 C GLU 77 ? C GLU 17 
52 1 Y 1 C ALA 78 ? C ALA 18 
53 1 Y 1 C ALA 79 ? C ALA 19 
54 1 Y 1 C ALA 80 ? C ALA 20 
55 1 Y 1 C ALA 81 ? C ALA 21 
56 1 Y 1 C SER 82 ? C SER 22 
57 1 Y 1 C GLU 83 ? C GLU 23 
58 1 Y 1 C GLU 84 ? C GLU 24 
59 1 Y 1 D HIS 61 ? D HIS 1  
60 1 Y 1 D ALA 62 ? D ALA 2  
61 1 Y 1 D MET 63 ? D MET 3  
62 1 Y 1 D VAL 64 ? D VAL 4  
63 1 Y 1 D SER 65 ? D SER 5  
64 1 Y 1 D ASN 66 ? D ASN 6  
65 1 Y 1 D ALA 67 ? D ALA 7  
66 1 Y 1 D GLU 68 ? D GLU 8  
67 1 Y 1 D THR 69 ? D THR 9  
68 1 Y 1 D GLU 70 ? D GLU 10 
69 1 Y 1 D THR 71 ? D THR 11 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
PYR C    C N N 290 
PYR O    O N N 291 
PYR OXT  O N N 292 
PYR CA   C N N 293 
PYR O3   O N N 294 
PYR CB   C N N 295 
PYR HXT  H N N 296 
PYR HB1  H N N 297 
PYR HB2  H N N 298 
PYR HB3  H N N 299 
SER N    N N N 300 
SER CA   C N S 301 
SER C    C N N 302 
SER O    O N N 303 
SER CB   C N N 304 
SER OG   O N N 305 
SER OXT  O N N 306 
SER H    H N N 307 
SER H2   H N N 308 
SER HA   H N N 309 
SER HB2  H N N 310 
SER HB3  H N N 311 
SER HG   H N N 312 
SER HXT  H N N 313 
THR N    N N N 314 
THR CA   C N S 315 
THR C    C N N 316 
THR O    O N N 317 
THR CB   C N R 318 
THR OG1  O N N 319 
THR CG2  C N N 320 
THR OXT  O N N 321 
THR H    H N N 322 
THR H2   H N N 323 
THR HA   H N N 324 
THR HB   H N N 325 
THR HG1  H N N 326 
THR HG21 H N N 327 
THR HG22 H N N 328 
THR HG23 H N N 329 
THR HXT  H N N 330 
TRP N    N N N 331 
TRP CA   C N S 332 
TRP C    C N N 333 
TRP O    O N N 334 
TRP CB   C N N 335 
TRP CG   C Y N 336 
TRP CD1  C Y N 337 
TRP CD2  C Y N 338 
TRP NE1  N Y N 339 
TRP CE2  C Y N 340 
TRP CE3  C Y N 341 
TRP CZ2  C Y N 342 
TRP CZ3  C Y N 343 
TRP CH2  C Y N 344 
TRP OXT  O N N 345 
TRP H    H N N 346 
TRP H2   H N N 347 
TRP HA   H N N 348 
TRP HB2  H N N 349 
TRP HB3  H N N 350 
TRP HD1  H N N 351 
TRP HE1  H N N 352 
TRP HE3  H N N 353 
TRP HZ2  H N N 354 
TRP HZ3  H N N 355 
TRP HH2  H N N 356 
TRP HXT  H N N 357 
TYR N    N N N 358 
TYR CA   C N S 359 
TYR C    C N N 360 
TYR O    O N N 361 
TYR CB   C N N 362 
TYR CG   C Y N 363 
TYR CD1  C Y N 364 
TYR CD2  C Y N 365 
TYR CE1  C Y N 366 
TYR CE2  C Y N 367 
TYR CZ   C Y N 368 
TYR OH   O N N 369 
TYR OXT  O N N 370 
TYR H    H N N 371 
TYR H2   H N N 372 
TYR HA   H N N 373 
TYR HB2  H N N 374 
TYR HB3  H N N 375 
TYR HD1  H N N 376 
TYR HD2  H N N 377 
TYR HE1  H N N 378 
TYR HE2  H N N 379 
TYR HH   H N N 380 
TYR HXT  H N N 381 
VAL N    N N N 382 
VAL CA   C N S 383 
VAL C    C N N 384 
VAL O    O N N 385 
VAL CB   C N N 386 
VAL CG1  C N N 387 
VAL CG2  C N N 388 
VAL OXT  O N N 389 
VAL H    H N N 390 
VAL H2   H N N 391 
VAL HA   H N N 392 
VAL HB   H N N 393 
VAL HG11 H N N 394 
VAL HG12 H N N 395 
VAL HG13 H N N 396 
VAL HG21 H N N 397 
VAL HG22 H N N 398 
VAL HG23 H N N 399 
VAL HXT  H N N 400 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
PYR C   O    doub N N 277 
PYR C   OXT  sing N N 278 
PYR C   CA   sing N N 279 
PYR OXT HXT  sing N N 280 
PYR CA  O3   doub N N 281 
PYR CA  CB   sing N N 282 
PYR CB  HB1  sing N N 283 
PYR CB  HB2  sing N N 284 
PYR CB  HB3  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
THR N   CA   sing N N 299 
THR N   H    sing N N 300 
THR N   H2   sing N N 301 
THR CA  C    sing N N 302 
THR CA  CB   sing N N 303 
THR CA  HA   sing N N 304 
THR C   O    doub N N 305 
THR C   OXT  sing N N 306 
THR CB  OG1  sing N N 307 
THR CB  CG2  sing N N 308 
THR CB  HB   sing N N 309 
THR OG1 HG1  sing N N 310 
THR CG2 HG21 sing N N 311 
THR CG2 HG22 sing N N 312 
THR CG2 HG23 sing N N 313 
THR OXT HXT  sing N N 314 
TRP N   CA   sing N N 315 
TRP N   H    sing N N 316 
TRP N   H2   sing N N 317 
TRP CA  C    sing N N 318 
TRP CA  CB   sing N N 319 
TRP CA  HA   sing N N 320 
TRP C   O    doub N N 321 
TRP C   OXT  sing N N 322 
TRP CB  CG   sing N N 323 
TRP CB  HB2  sing N N 324 
TRP CB  HB3  sing N N 325 
TRP CG  CD1  doub Y N 326 
TRP CG  CD2  sing Y N 327 
TRP CD1 NE1  sing Y N 328 
TRP CD1 HD1  sing N N 329 
TRP CD2 CE2  doub Y N 330 
TRP CD2 CE3  sing Y N 331 
TRP NE1 CE2  sing Y N 332 
TRP NE1 HE1  sing N N 333 
TRP CE2 CZ2  sing Y N 334 
TRP CE3 CZ3  doub Y N 335 
TRP CE3 HE3  sing N N 336 
TRP CZ2 CH2  doub Y N 337 
TRP CZ2 HZ2  sing N N 338 
TRP CZ3 CH2  sing Y N 339 
TRP CZ3 HZ3  sing N N 340 
TRP CH2 HH2  sing N N 341 
TRP OXT HXT  sing N N 342 
TYR N   CA   sing N N 343 
TYR N   H    sing N N 344 
TYR N   H2   sing N N 345 
TYR CA  C    sing N N 346 
TYR CA  CB   sing N N 347 
TYR CA  HA   sing N N 348 
TYR C   O    doub N N 349 
TYR C   OXT  sing N N 350 
TYR CB  CG   sing N N 351 
TYR CB  HB2  sing N N 352 
TYR CB  HB3  sing N N 353 
TYR CG  CD1  doub Y N 354 
TYR CG  CD2  sing Y N 355 
TYR CD1 CE1  sing Y N 356 
TYR CD1 HD1  sing N N 357 
TYR CD2 CE2  doub Y N 358 
TYR CD2 HD2  sing N N 359 
TYR CE1 CZ   doub Y N 360 
TYR CE1 HE1  sing N N 361 
TYR CE2 CZ   sing Y N 362 
TYR CE2 HE2  sing N N 363 
TYR CZ  OH   sing N N 364 
TYR OH  HH   sing N N 365 
TYR OXT HXT  sing N N 366 
VAL N   CA   sing N N 367 
VAL N   H    sing N N 368 
VAL N   H2   sing N N 369 
VAL CA  C    sing N N 370 
VAL CA  CB   sing N N 371 
VAL CA  HA   sing N N 372 
VAL C   O    doub N N 373 
VAL C   OXT  sing N N 374 
VAL CB  CG1  sing N N 375 
VAL CB  CG2  sing N N 376 
VAL CB  HB   sing N N 377 
VAL CG1 HG11 sing N N 378 
VAL CG1 HG12 sing N N 379 
VAL CG1 HG13 sing N N 380 
VAL CG2 HG21 sing N N 381 
VAL CG2 HG22 sing N N 382 
VAL CG2 HG23 sing N N 383 
VAL OXT HXT  sing N N 384 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'German Research Foundation (DFG)'                                Germany   'Grant MA2379/20-1 to VM' 1 
'Agencia Nacional de Promocion Cientifica y Tecnologica (FONCYT)' Argentina PICT-2019-00079           2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5OU5 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9E6M 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010134 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008054 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005278 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . GLU A 1 12  ? -88.087  -4.646  45.168  1.00 126.99 ? 72  GLU A N   1 
ATOM   2     C CA  . GLU A 1 12  ? -88.354  -4.296  46.602  1.00 130.96 ? 72  GLU A CA  1 
ATOM   3     C C   . GLU A 1 12  ? -87.391  -5.100  47.521  1.00 144.52 ? 72  GLU A C   1 
ATOM   4     O O   . GLU A 1 12  ? -86.486  -4.464  48.134  1.00 140.10 ? 72  GLU A O   1 
ATOM   5     C CB  . GLU A 1 12  ? -89.867  -4.392  46.884  1.00 116.90 ? 72  GLU A CB  1 
ATOM   6     C CG  . GLU A 1 12  ? -90.478  -5.798  46.856  1.00 130.66 ? 72  GLU A CG  1 
ATOM   7     C CD  . GLU A 1 12  ? -90.401  -6.576  45.544  1.00 125.70 ? 72  GLU A CD  1 
ATOM   8     O OE1 . GLU A 1 12  ? -90.430  -5.935  44.479  1.00 115.58 ? 72  GLU A OE1 1 
ATOM   9     O OE2 . GLU A 1 12  ? -90.285  -7.825  45.586  1.00 117.87 ? 72  GLU A OE2 1 
ATOM   10    N N   . LYS A 1 13  ? -87.509  -6.432  47.584  1.00 152.77 ? 73  LYS A N   1 
ATOM   11    C CA  . LYS A 1 13  ? -86.715  -7.315  48.487  1.00 148.54 ? 73  LYS A CA  1 
ATOM   12    C C   . LYS A 1 13  ? -85.437  -7.776  47.769  1.00 148.86 ? 73  LYS A C   1 
ATOM   13    O O   . LYS A 1 13  ? -84.620  -8.456  48.408  1.00 161.26 ? 73  LYS A O   1 
ATOM   14    C CB  . LYS A 1 13  ? -87.570  -8.507  48.932  1.00 156.33 ? 73  LYS A CB  1 
ATOM   15    C CG  . LYS A 1 13  ? -88.863  -8.151  49.666  1.00 157.16 ? 73  LYS A CG  1 
ATOM   16    C CD  . LYS A 1 13  ? -88.668  -7.862  51.148  1.00 153.46 ? 73  LYS A CD  1 
ATOM   17    C CE  . LYS A 1 13  ? -89.951  -7.853  51.956  1.00 124.25 ? 73  LYS A CE  1 
ATOM   18    N NZ  . LYS A 1 13  ? -89.648  -7.824  53.406  1.00 109.92 ? 73  LYS A NZ  1 
ATOM   19    N N   . GLU A 1 14  ? -85.310  -7.475  46.470  1.00 139.10 ? 74  GLU A N   1 
ATOM   20    C CA  . GLU A 1 14  ? -84.096  -7.719  45.646  1.00 126.90 ? 74  GLU A CA  1 
ATOM   21    C C   . GLU A 1 14  ? -83.853  -6.448  44.814  1.00 126.07 ? 74  GLU A C   1 
ATOM   22    O O   . GLU A 1 14  ? -83.738  -6.549  43.583  1.00 116.32 ? 74  GLU A O   1 
ATOM   23    C CB  . GLU A 1 14  ? -84.270  -8.981  44.788  1.00 128.37 ? 74  GLU A CB  1 
ATOM   24    C CG  . GLU A 1 14  ? -85.053  -10.116 45.442  1.00 130.13 ? 74  GLU A CG  1 
ATOM   25    C CD  . GLU A 1 14  ? -86.577  -10.065 45.339  1.00 151.63 ? 74  GLU A CD  1 
ATOM   26    O OE1 . GLU A 1 14  ? -87.138  -9.277  44.519  1.00 149.91 ? 74  GLU A OE1 1 
ATOM   27    O OE2 . GLU A 1 14  ? -87.208  -10.824 46.085  1.00 161.32 ? 74  GLU A OE2 1 
ATOM   28    N N   . GLN A 1 15  ? -83.807  -5.288  45.483  1.00 131.75 ? 75  GLN A N   1 
ATOM   29    C CA  . GLN A 1 15  ? -83.552  -3.942  44.890  1.00 124.63 ? 75  GLN A CA  1 
ATOM   30    C C   . GLN A 1 15  ? -82.067  -3.805  44.537  1.00 133.99 ? 75  GLN A C   1 
ATOM   31    O O   . GLN A 1 15  ? -81.285  -3.287  45.364  1.00 133.20 ? 75  GLN A O   1 
ATOM   32    C CB  . GLN A 1 15  ? -83.943  -2.835  45.865  1.00 120.86 ? 75  GLN A CB  1 
ATOM   33    C CG  . GLN A 1 15  ? -85.440  -2.579  45.902  1.00 125.61 ? 75  GLN A CG  1 
ATOM   34    C CD  . GLN A 1 15  ? -85.864  -1.477  44.965  1.00 121.75 ? 75  GLN A CD  1 
ATOM   35    O OE1 . GLN A 1 15  ? -85.031  -0.746  44.435  1.00 117.55 ? 75  GLN A OE1 1 
ATOM   36    N NE2 . GLN A 1 15  ? -87.168  -1.335  44.777  1.00 100.02 ? 75  GLN A NE2 1 
ATOM   37    N N   . GLU A 1 16  ? -81.713  -4.291  43.349  1.00 125.59 ? 76  GLU A N   1 
ATOM   38    C CA  . GLU A 1 16  ? -80.323  -4.384  42.851  1.00 92.40  ? 76  GLU A CA  1 
ATOM   39    C C   . GLU A 1 16  ? -79.967  -3.112  42.090  1.00 93.30  ? 76  GLU A C   1 
ATOM   40    O O   . GLU A 1 16  ? -78.961  -3.156  41.359  1.00 86.59  ? 76  GLU A O   1 
ATOM   41    C CB  . GLU A 1 16  ? -80.220  -5.576  41.919  1.00 76.70  ? 76  GLU A CB  1 
ATOM   42    C CG  . GLU A 1 16  ? -78.802  -6.018  41.681  1.00 72.62  ? 76  GLU A CG  1 
ATOM   43    C CD  . GLU A 1 16  ? -78.754  -7.516  41.521  1.00 70.05  ? 76  GLU A CD  1 
ATOM   44    O OE1 . GLU A 1 16  ? -79.703  -8.175  42.023  1.00 75.13  ? 76  GLU A OE1 1 
ATOM   45    O OE2 . GLU A 1 16  ? -77.817  -8.015  40.874  1.00 54.53  ? 76  GLU A OE2 1 
ATOM   46    N N   . GLU A 1 17  ? -80.776  -2.049  42.216  1.00 100.13 ? 77  GLU A N   1 
ATOM   47    C CA  . GLU A 1 17  ? -80.514  -0.728  41.572  1.00 122.51 ? 77  GLU A CA  1 
ATOM   48    C C   . GLU A 1 17  ? -79.322  -0.068  42.287  1.00 135.52 ? 77  GLU A C   1 
ATOM   49    O O   . GLU A 1 17  ? -78.470  0.518   41.589  1.00 114.88 ? 77  GLU A O   1 
ATOM   50    C CB  . GLU A 1 17  ? -81.770  0.155   41.546  1.00 126.61 ? 77  GLU A CB  1 
ATOM   51    C CG  . GLU A 1 17  ? -82.616  0.091   42.808  1.00 129.88 ? 77  GLU A CG  1 
ATOM   52    C CD  . GLU A 1 17  ? -83.580  1.249   43.007  1.00 129.60 ? 77  GLU A CD  1 
ATOM   53    O OE1 . GLU A 1 17  ? -83.780  2.034   42.051  1.00 124.58 ? 77  GLU A OE1 1 
ATOM   54    O OE2 . GLU A 1 17  ? -84.125  1.366   44.128  1.00 107.80 ? 77  GLU A OE2 1 
ATOM   55    N N   . ALA A 1 18  ? -79.253  -0.219  43.619  1.00 152.35 ? 78  ALA A N   1 
ATOM   56    C CA  . ALA A 1 18  ? -78.184  0.284   44.518  1.00 130.72 ? 78  ALA A CA  1 
ATOM   57    C C   . ALA A 1 18  ? -76.893  -0.563  44.397  1.00 125.68 ? 78  ALA A C   1 
ATOM   58    O O   . ALA A 1 18  ? -75.821  -0.042  44.780  1.00 114.80 ? 78  ALA A O   1 
ATOM   59    C CB  . ALA A 1 18  ? -78.724  0.324   45.936  1.00 106.04 ? 78  ALA A CB  1 
ATOM   60    N N   . ALA A 1 19  ? -76.974  -1.807  43.881  1.00 119.93 ? 79  ALA A N   1 
ATOM   61    C CA  . ALA A 1 19  ? -75.852  -2.782  43.724  1.00 110.43 ? 79  ALA A CA  1 
ATOM   62    C C   . ALA A 1 19  ? -75.188  -2.658  42.334  1.00 113.77 ? 79  ALA A C   1 
ATOM   63    O O   . ALA A 1 19  ? -74.058  -3.172  42.151  1.00 108.10 ? 79  ALA A O   1 
ATOM   64    C CB  . ALA A 1 19  ? -76.335  -4.199  43.970  1.00 89.36  ? 79  ALA A CB  1 
ATOM   65    N N   . ALA A 1 20  ? -75.860  -2.019  41.369  1.00 106.81 ? 80  ALA A N   1 
ATOM   66    C CA  . ALA A 1 20  ? -75.298  -1.575  40.072  1.00 86.31  ? 80  ALA A CA  1 
ATOM   67    C C   . ALA A 1 20  ? -74.866  -0.096  40.178  1.00 90.56  ? 80  ALA A C   1 
ATOM   68    O O   . ALA A 1 20  ? -75.161  0.705   39.267  1.00 73.99  ? 80  ALA A O   1 
ATOM   69    C CB  . ALA A 1 20  ? -76.320  -1.788  38.996  1.00 91.85  ? 80  ALA A CB  1 
ATOM   70    N N   . ALA A 1 21  ? -74.197  0.253   41.285  1.00 102.79 ? 81  ALA A N   1 
ATOM   71    C CA  . ALA A 1 21  ? -73.203  1.354   41.401  1.00 104.91 ? 81  ALA A CA  1 
ATOM   72    C C   . ALA A 1 21  ? -71.813  0.732   41.658  1.00 110.28 ? 81  ALA A C   1 
ATOM   73    O O   . ALA A 1 21  ? -70.964  1.390   42.317  1.00 95.73  ? 81  ALA A O   1 
ATOM   74    C CB  . ALA A 1 21  ? -73.608  2.322   42.488  1.00 99.85  ? 81  ALA A CB  1 
ATOM   75    N N   . SER A 1 22  ? -71.582  -0.481  41.117  1.00 110.08 ? 82  SER A N   1 
ATOM   76    C CA  . SER A 1 22  ? -70.324  -1.282  41.178  1.00 102.04 ? 82  SER A CA  1 
ATOM   77    C C   . SER A 1 22  ? -69.451  -1.007  39.943  1.00 93.46  ? 82  SER A C   1 
ATOM   78    O O   . SER A 1 22  ? -69.075  -1.960  39.279  1.00 107.36 ? 82  SER A O   1 
ATOM   79    C CB  . SER A 1 22  ? -70.614  -2.791  41.288  1.00 96.62  ? 82  SER A CB  1 
ATOM   80    O OG  . SER A 1 22  ? -70.957  -3.203  42.606  1.00 86.85  ? 82  SER A OG  1 
ATOM   81    N N   . GLU A 1 23  ? -69.143  0.250   39.646  1.00 102.75 ? 83  GLU A N   1 
ATOM   82    C CA  . GLU A 1 23  ? -68.272  0.651   38.509  1.00 111.55 ? 83  GLU A CA  1 
ATOM   83    C C   . GLU A 1 23  ? -67.107  1.470   39.081  1.00 112.83 ? 83  GLU A C   1 
ATOM   84    O O   . GLU A 1 23  ? -65.961  1.099   38.803  1.00 113.59 ? 83  GLU A O   1 
ATOM   85    C CB  . GLU A 1 23  ? -69.115  1.362   37.432  1.00 123.79 ? 83  GLU A CB  1 
ATOM   86    C CG  . GLU A 1 23  ? -69.108  2.892   37.429  1.00 125.96 ? 83  GLU A CG  1 
ATOM   87    C CD  . GLU A 1 23  ? -69.977  3.664   38.429  1.00 123.93 ? 83  GLU A CD  1 
ATOM   88    O OE1 . GLU A 1 23  ? -70.197  3.179   39.574  1.00 121.81 ? 83  GLU A OE1 1 
ATOM   89    O OE2 . GLU A 1 23  ? -70.403  4.780   38.076  1.00 101.87 ? 83  GLU A OE2 1 
ATOM   90    N N   . GLU A 1 24  ? -67.398  2.528   39.857  1.00 114.64 ? 84  GLU A N   1 
ATOM   91    C CA  . GLU A 1 24  ? -66.407  3.371   40.581  1.00 100.90 ? 84  GLU A CA  1 
ATOM   92    C C   . GLU A 1 24  ? -66.287  2.874   42.029  1.00 86.09  ? 84  GLU A C   1 
ATOM   93    O O   . GLU A 1 24  ? -65.760  3.622   42.845  1.00 81.76  ? 84  GLU A O   1 
ATOM   94    C CB  . GLU A 1 24  ? -66.781  4.866   40.609  1.00 107.01 ? 84  GLU A CB  1 
ATOM   95    C CG  . GLU A 1 24  ? -67.409  5.434   39.346  1.00 106.74 ? 84  GLU A CG  1 
ATOM   96    C CD  . GLU A 1 24  ? -66.461  5.769   38.206  1.00 108.94 ? 84  GLU A CD  1 
ATOM   97    O OE1 . GLU A 1 24  ? -65.263  5.444   38.320  1.00 117.44 ? 84  GLU A OE1 1 
ATOM   98    O OE2 . GLU A 1 24  ? -66.918  6.357   37.207  1.00 96.38  ? 84  GLU A OE2 1 
ATOM   99    N N   . LEU A 1 25  ? -66.793  1.683   42.366  1.00 82.03  ? 85  LEU A N   1 
ATOM   100   C CA  . LEU A 1 25  ? -66.528  1.051   43.689  1.00 77.30  ? 85  LEU A CA  1 
ATOM   101   C C   . LEU A 1 25  ? -65.063  0.629   43.707  1.00 84.69  ? 85  LEU A C   1 
ATOM   102   O O   . LEU A 1 25  ? -64.642  -0.098  42.806  1.00 77.87  ? 85  LEU A O   1 
ATOM   103   C CB  . LEU A 1 25  ? -67.463  -0.147  43.860  1.00 77.77  ? 85  LEU A CB  1 
ATOM   104   C CG  . LEU A 1 25  ? -67.566  -0.751  45.258  1.00 71.58  ? 85  LEU A CG  1 
ATOM   105   C CD1 . LEU A 1 25  ? -68.405  0.136   46.171  1.00 77.04  ? 85  LEU A CD1 1 
ATOM   106   C CD2 . LEU A 1 25  ? -68.160  -2.157  45.175  1.00 64.77  ? 85  LEU A CD2 1 
ATOM   107   N N   . PRO A 1 26  ? -64.221  1.086   44.677  1.00 85.89  ? 86  PRO A N   1 
ATOM   108   C CA  . PRO A 1 26  ? -62.857  0.570   44.754  1.00 79.44  ? 86  PRO A CA  1 
ATOM   109   C C   . PRO A 1 26  ? -62.943  -0.962  44.899  1.00 68.78  ? 86  PRO A C   1 
ATOM   110   O O   . PRO A 1 26  ? -63.805  -1.441  45.618  1.00 64.80  ? 86  PRO A O   1 
ATOM   111   C CB  . PRO A 1 26  ? -62.269  1.283   45.990  1.00 82.00  ? 86  PRO A CB  1 
ATOM   112   C CG  . PRO A 1 26  ? -63.089  2.547   46.128  1.00 74.32  ? 86  PRO A CG  1 
ATOM   113   C CD  . PRO A 1 26  ? -64.483  2.125   45.697  1.00 76.63  ? 86  PRO A CD  1 
ATOM   114   N N   . VAL A 1 27  ? -62.079  -1.709  44.225  1.00 64.34  ? 87  VAL A N   1 
ATOM   115   C CA  . VAL A 1 27  ? -61.977  -3.179  44.479  1.00 63.33  ? 87  VAL A CA  1 
ATOM   116   C C   . VAL A 1 27  ? -60.506  -3.595  44.538  1.00 56.49  ? 87  VAL A C   1 
ATOM   117   O O   . VAL A 1 27  ? -59.621  -2.893  44.043  1.00 54.85  ? 87  VAL A O   1 
ATOM   118   C CB  . VAL A 1 27  ? -62.756  -3.976  43.431  1.00 58.59  ? 87  VAL A CB  1 
ATOM   119   C CG1 . VAL A 1 27  ? -64.239  -3.885  43.701  1.00 59.53  ? 87  VAL A CG1 1 
ATOM   120   C CG2 . VAL A 1 27  ? -62.415  -3.482  42.047  1.00 59.52  ? 87  VAL A CG2 1 
ATOM   121   N N   . MET A 1 28  ? -60.259  -4.708  45.199  1.00 55.58  ? 88  MET A N   1 
ATOM   122   C CA  . MET A 1 28  ? -58.914  -5.302  45.314  1.00 63.73  ? 88  MET A CA  1 
ATOM   123   C C   . MET A 1 28  ? -58.869  -6.483  44.366  1.00 64.60  ? 88  MET A C   1 
ATOM   124   O O   . MET A 1 28  ? -59.732  -7.337  44.465  1.00 74.51  ? 88  MET A O   1 
ATOM   125   C CB  . MET A 1 28  ? -58.640  -5.790  46.738  1.00 69.65  ? 88  MET A CB  1 
ATOM   126   C CG  . MET A 1 28  ? -57.202  -6.178  46.971  1.00 73.31  ? 88  MET A CG  1 
ATOM   127   S SD  . MET A 1 28  ? -56.254  -4.771  47.682  1.00 74.95  ? 88  MET A SD  1 
ATOM   128   C CE  . MET A 1 28  ? -56.041  -3.683  46.269  1.00 74.79  ? 88  MET A CE  1 
ATOM   129   N N   . PRO A 1 29  ? -57.897  -6.572  43.426  1.00 55.13  ? 89  PRO A N   1 
ATOM   130   C CA  . PRO A 1 29  ? -57.743  -7.768  42.604  1.00 51.93  ? 89  PRO A CA  1 
ATOM   131   C C   . PRO A 1 29  ? -57.149  -8.971  43.357  1.00 46.63  ? 89  PRO A C   1 
ATOM   132   O O   . PRO A 1 29  ? -56.014  -9.114  43.386  1.00 50.36  ? 89  PRO A O   1 
ATOM   133   C CB  . PRO A 1 29  ? -56.818  -7.274  41.497  1.00 52.88  ? 89  PRO A CB  1 
ATOM   134   C CG  . PRO A 1 29  ? -55.984  -6.209  42.152  1.00 52.59  ? 89  PRO A CG  1 
ATOM   135   C CD  . PRO A 1 29  ? -56.914  -5.529  43.116  1.00 48.43  ? 89  PRO A CD  1 
ATOM   136   N N   . TRP A 1 30  ? -57.994  -9.802  43.951  1.00 49.52  ? 90  TRP A N   1 
ATOM   137   C CA  . TRP A 1 30  ? -57.608  -10.994 44.750  1.00 50.74  ? 90  TRP A CA  1 
ATOM   138   C C   . TRP A 1 30  ? -57.138  -12.058 43.772  1.00 48.40  ? 90  TRP A C   1 
ATOM   139   O O   . TRP A 1 30  ? -57.723  -12.165 42.712  1.00 56.78  ? 90  TRP A O   1 
ATOM   140   C CB  . TRP A 1 30  ? -58.764  -11.486 45.664  1.00 54.62  ? 90  TRP A CB  1 
ATOM   141   C CG  . TRP A 1 30  ? -59.137  -10.454 46.684  1.00 56.56  ? 90  TRP A CG  1 
ATOM   142   C CD1 . TRP A 1 30  ? -60.212  -9.612  46.659  1.00 54.46  ? 90  TRP A CD1 1 
ATOM   143   C CD2 . TRP A 1 30  ? -58.339  -10.044 47.806  1.00 54.86  ? 90  TRP A CD2 1 
ATOM   144   N NE1 . TRP A 1 30  ? -60.153  -8.733  47.701  1.00 52.27  ? 90  TRP A NE1 1 
ATOM   145   C CE2 . TRP A 1 30  ? -58.989  -8.947  48.394  1.00 51.54  ? 90  TRP A CE2 1 
ATOM   146   C CE3 . TRP A 1 30  ? -57.144  -10.505 48.361  1.00 60.20  ? 90  TRP A CE3 1 
ATOM   147   C CZ2 . TRP A 1 30  ? -58.497  -8.336  49.544  1.00 56.06  ? 90  TRP A CZ2 1 
ATOM   148   C CZ3 . TRP A 1 30  ? -56.648  -9.876  49.481  1.00 62.69  ? 90  TRP A CZ3 1 
ATOM   149   C CH2 . TRP A 1 30  ? -57.329  -8.817  50.074  1.00 54.18  ? 90  TRP A CH2 1 
ATOM   150   N N   . ALA A 1 31  ? -56.106  -12.815 44.117  1.00 48.98  ? 91  ALA A N   1 
ATOM   151   C CA  . ALA A 1 31  ? -55.768  -14.079 43.420  1.00 54.62  ? 91  ALA A CA  1 
ATOM   152   C C   . ALA A 1 31  ? -55.988  -15.245 44.382  1.00 48.45  ? 91  ALA A C   1 
ATOM   153   O O   . ALA A 1 31  ? -55.656  -15.070 45.546  1.00 49.50  ? 91  ALA A O   1 
ATOM   154   C CB  . ALA A 1 31  ? -54.346  -13.993 42.939  1.00 56.34  ? 91  ALA A CB  1 
ATOM   155   N N   . THR A 1 32  ? -56.503  -16.380 43.921  1.00 52.91  ? 92  THR A N   1 
ATOM   156   C CA  . THR A 1 32  ? -56.601  -17.622 44.747  1.00 59.78  ? 92  THR A CA  1 
ATOM   157   C C   . THR A 1 32  ? -55.495  -18.606 44.355  1.00 55.40  ? 92  THR A C   1 
ATOM   158   O O   . THR A 1 32  ? -55.258  -18.785 43.162  1.00 57.35  ? 92  THR A O   1 
ATOM   159   C CB  . THR A 1 32  ? -57.989  -18.269 44.693  1.00 69.38  ? 92  THR A CB  1 
ATOM   160   O OG1 . THR A 1 32  ? -58.588  -18.004 43.427  1.00 77.19  ? 92  THR A OG1 1 
ATOM   161   C CG2 . THR A 1 32  ? -58.907  -17.779 45.799  1.00 84.34  ? 92  THR A CG2 1 
ATOM   162   N N   . SER A 1 33  ? -54.835  -19.216 45.338  1.00 48.76  ? 93  SER A N   1 
ATOM   163   C CA  . SER A 1 33  ? -53.788  -20.244 45.104  1.00 48.53  ? 93  SER A CA  1 
ATOM   164   C C   . SER A 1 33  ? -53.913  -21.374 46.121  1.00 43.15  ? 93  SER A C   1 
ATOM   165   O O   . SER A 1 33  ? -54.292  -21.082 47.275  1.00 42.57  ? 93  SER A O   1 
ATOM   166   C CB  . SER A 1 33  ? -52.446  -19.630 45.175  1.00 49.15  ? 93  SER A CB  1 
ATOM   167   O OG  . SER A 1 33  ? -52.180  -19.243 46.515  1.00 53.28  ? 93  SER A OG  1 
ATOM   168   N N   . VAL A 1 34  ? -53.575  -22.599 45.716  1.00 42.27  ? 94  VAL A N   1 
ATOM   169   C CA  . VAL A 1 34  ? -53.506  -23.764 46.647  1.00 50.54  ? 94  VAL A CA  1 
ATOM   170   C C   . VAL A 1 34  ? -52.451  -23.433 47.702  1.00 53.75  ? 94  VAL A C   1 
ATOM   171   O O   . VAL A 1 34  ? -51.355  -23.084 47.306  1.00 56.15  ? 94  VAL A O   1 
ATOM   172   C CB  . VAL A 1 34  ? -53.155  -25.085 45.946  1.00 50.24  ? 94  VAL A CB  1 
ATOM   173   C CG1 . VAL A 1 34  ? -53.113  -26.229 46.942  1.00 50.35  ? 94  VAL A CG1 1 
ATOM   174   C CG2 . VAL A 1 34  ? -54.125  -25.391 44.818  1.00 50.93  ? 94  VAL A CG2 1 
ATOM   175   N N   . ALA A 1 35  ? -52.791  -23.516 48.990  1.00 50.76  ? 95  ALA A N   1 
ATOM   176   C CA  . ALA A 1 35  ? -51.851  -23.356 50.112  1.00 50.95  ? 95  ALA A CA  1 
ATOM   177   C C   . ALA A 1 35  ? -51.112  -24.688 50.389  1.00 53.45  ? 95  ALA A C   1 
ATOM   178   O O   . ALA A 1 35  ? -51.739  -25.791 50.393  1.00 44.05  ? 95  ALA A O   1 
ATOM   179   C CB  . ALA A 1 35  ? -52.611  -22.872 51.309  1.00 54.23  ? 95  ALA A CB  1 
ATOM   180   N N   . SER A 1 36  ? -49.798  -24.575 50.591  1.00 57.12  ? 96  SER A N   1 
ATOM   181   C CA  . SER A 1 36  ? -48.883  -25.659 51.033  1.00 60.99  ? 96  SER A CA  1 
ATOM   182   C C   . SER A 1 36  ? -47.688  -25.063 51.813  1.00 61.81  ? 96  SER A C   1 
ATOM   183   O O   . SER A 1 36  ? -47.617  -23.809 51.960  1.00 49.23  ? 96  SER A O   1 
ATOM   184   C CB  . SER A 1 36  ? -48.466  -26.487 49.853  1.00 69.49  ? 96  SER A CB  1 
ATOM   185   O OG  . SER A 1 36  ? -48.281  -25.663 48.703  1.00 84.44  ? 96  SER A OG  1 
ATOM   186   N N   . GLY A 1 37  ? -46.821  -25.933 52.361  1.00 63.97  ? 97  GLY A N   1 
ATOM   187   C CA  . GLY A 1 37  ? -45.647  -25.562 53.185  1.00 55.65  ? 97  GLY A CA  1 
ATOM   188   C C   . GLY A 1 37  ? -45.962  -24.454 54.191  1.00 47.84  ? 97  GLY A C   1 
ATOM   189   O O   . GLY A 1 37  ? -47.022  -24.490 54.818  1.00 49.00  ? 97  GLY A O   1 
ATOM   190   N N   . TYR A 1 38  ? -45.076  -23.477 54.340  1.00 48.74  ? 98  TYR A N   1 
ATOM   191   C CA  . TYR A 1 38  ? -45.171  -22.392 55.356  1.00 49.71  ? 98  TYR A CA  1 
ATOM   192   C C   . TYR A 1 38  ? -46.385  -21.482 55.110  1.00 49.82  ? 98  TYR A C   1 
ATOM   193   O O   . TYR A 1 38  ? -46.900  -20.941 56.122  1.00 55.01  ? 98  TYR A O   1 
ATOM   194   C CB  . TYR A 1 38  ? -43.863  -21.596 55.506  1.00 47.71  ? 98  TYR A CB  1 
ATOM   195   C CG  . TYR A 1 38  ? -42.894  -22.256 56.451  1.00 48.86  ? 98  TYR A CG  1 
ATOM   196   C CD1 . TYR A 1 38  ? -43.099  -22.215 57.817  1.00 52.65  ? 98  TYR A CD1 1 
ATOM   197   C CD2 . TYR A 1 38  ? -41.830  -23.014 55.986  1.00 54.25  ? 98  TYR A CD2 1 
ATOM   198   C CE1 . TYR A 1 38  ? -42.258  -22.878 58.700  1.00 58.91  ? 98  TYR A CE1 1 
ATOM   199   C CE2 . TYR A 1 38  ? -40.973  -23.674 56.851  1.00 54.29  ? 98  TYR A CE2 1 
ATOM   200   C CZ  . TYR A 1 38  ? -41.185  -23.610 58.217  1.00 62.75  ? 98  TYR A CZ  1 
ATOM   201   O OH  . TYR A 1 38  ? -40.358  -24.263 59.092  1.00 77.72  ? 98  TYR A OH  1 
ATOM   202   N N   . THR A 1 39  ? -46.865  -21.336 53.872  1.00 47.21  ? 99  THR A N   1 
ATOM   203   C CA  . THR A 1 39  ? -48.059  -20.505 53.581  1.00 53.81  ? 99  THR A CA  1 
ATOM   204   C C   . THR A 1 39  ? -49.259  -21.101 54.330  1.00 59.49  ? 99  THR A C   1 
ATOM   205   O O   . THR A 1 39  ? -49.941  -20.343 55.040  1.00 63.19  ? 99  THR A O   1 
ATOM   206   C CB  . THR A 1 39  ? -48.369  -20.383 52.087  1.00 58.57  ? 99  THR A CB  1 
ATOM   207   O OG1 . THR A 1 39  ? -47.177  -20.367 51.298  1.00 54.74  ? 99  THR A OG1 1 
ATOM   208   C CG2 . THR A 1 39  ? -49.177  -19.131 51.825  1.00 64.34  ? 99  THR A CG2 1 
ATOM   209   N N   . LEU A 1 40  ? -49.466  -22.419 54.202  1.00 62.14  ? 100 LEU A N   1 
ATOM   210   C CA  . LEU A 1 40  ? -50.545  -23.203 54.883  1.00 50.41  ? 100 LEU A CA  1 
ATOM   211   C C   . LEU A 1 40  ? -50.399  -23.124 56.407  1.00 48.14  ? 100 LEU A C   1 
ATOM   212   O O   . LEU A 1 40  ? -51.403  -22.874 57.072  1.00 53.43  ? 100 LEU A O   1 
ATOM   213   C CB  . LEU A 1 40  ? -50.477  -24.652 54.407  1.00 53.45  ? 100 LEU A CB  1 
ATOM   214   C CG  . LEU A 1 40  ? -51.550  -25.586 54.938  1.00 60.35  ? 100 LEU A CG  1 
ATOM   215   C CD1 . LEU A 1 40  ? -51.153  -26.182 56.243  1.00 68.29  ? 100 LEU A CD1 1 
ATOM   216   C CD2 . LEU A 1 40  ? -52.899  -24.904 55.034  1.00 64.49  ? 100 LEU A CD2 1 
ATOM   217   N N   . LEU A 1 41  ? -49.208  -23.338 56.963  1.00 49.12  ? 101 LEU A N   1 
ATOM   218   C CA  . LEU A 1 41  ? -48.980  -23.343 58.436  1.00 48.33  ? 101 LEU A CA  1 
ATOM   219   C C   . LEU A 1 41  ? -49.233  -21.952 59.014  1.00 49.29  ? 101 LEU A C   1 
ATOM   220   O O   . LEU A 1 41  ? -49.790  -21.882 60.116  1.00 51.10  ? 101 LEU A O   1 
ATOM   221   C CB  . LEU A 1 41  ? -47.553  -23.798 58.738  1.00 52.19  ? 101 LEU A CB  1 
ATOM   222   C CG  . LEU A 1 41  ? -47.222  -25.225 58.303  1.00 59.38  ? 101 LEU A CG  1 
ATOM   223   C CD1 . LEU A 1 41  ? -45.758  -25.515 58.526  1.00 64.79  ? 101 LEU A CD1 1 
ATOM   224   C CD2 . LEU A 1 41  ? -48.040  -26.255 59.064  1.00 63.65  ? 101 LEU A CD2 1 
ATOM   225   N N   . ARG A 1 42  ? -48.866  -20.885 58.299  1.00 50.59  ? 102 ARG A N   1 
ATOM   226   C CA  . ARG A 1 42  ? -49.005  -19.476 58.777  1.00 56.06  ? 102 ARG A CA  1 
ATOM   227   C C   . ARG A 1 42  ? -50.422  -18.945 58.532  1.00 60.23  ? 102 ARG A C   1 
ATOM   228   O O   . ARG A 1 42  ? -50.700  -17.805 58.996  1.00 55.67  ? 102 ARG A O   1 
ATOM   229   C CB  . ARG A 1 42  ? -47.959  -18.578 58.108  1.00 59.88  ? 102 ARG A CB  1 
ATOM   230   C CG  . ARG A 1 42  ? -46.528  -19.042 58.329  1.00 57.99  ? 102 ARG A CG  1 
ATOM   231   C CD  . ARG A 1 42  ? -45.527  -17.973 58.661  1.00 65.73  ? 102 ARG A CD  1 
ATOM   232   N NE  . ARG A 1 42  ? -44.228  -18.579 58.927  1.00 67.81  ? 102 ARG A NE  1 
ATOM   233   C CZ  . ARG A 1 42  ? -43.205  -18.637 58.069  1.00 61.48  ? 102 ARG A CZ  1 
ATOM   234   N NH1 . ARG A 1 42  ? -43.301  -18.117 56.860  1.00 64.80  ? 102 ARG A NH1 1 
ATOM   235   N NH2 . ARG A 1 42  ? -42.074  -19.207 58.430  1.00 60.69  ? 102 ARG A NH2 1 
ATOM   236   N N   . ASP A 1 43  ? -51.282  -19.731 57.847  1.00 58.33  ? 103 ASP A N   1 
ATOM   237   C CA  . ASP A 1 43  ? -52.730  -19.448 57.623  1.00 58.19  ? 103 ASP A CA  1 
ATOM   238   C C   . ASP A 1 43  ? -53.557  -19.998 58.783  1.00 52.90  ? 103 ASP A C   1 
ATOM   239   O O   . ASP A 1 43  ? -53.795  -21.200 58.916  1.00 56.26  ? 103 ASP A O   1 
ATOM   240   C CB  . ASP A 1 43  ? -53.235  -20.009 56.291  1.00 70.29  ? 103 ASP A CB  1 
ATOM   241   C CG  . ASP A 1 43  ? -54.700  -19.693 55.963  1.00 84.22  ? 103 ASP A CG  1 
ATOM   242   O OD1 . ASP A 1 43  ? -55.290  -18.773 56.588  1.00 94.92  ? 103 ASP A OD1 1 
ATOM   243   O OD2 . ASP A 1 43  ? -55.259  -20.371 55.081  1.00 90.70  ? 103 ASP A OD2 1 
ATOM   244   N N   . PRO A 1 44  ? -54.100  -19.109 59.640  1.00 43.68  ? 104 PRO A N   1 
ATOM   245   C CA  . PRO A 1 44  ? -54.875  -19.578 60.771  1.00 41.28  ? 104 PRO A CA  1 
ATOM   246   C C   . PRO A 1 44  ? -56.087  -20.391 60.325  1.00 47.25  ? 104 PRO A C   1 
ATOM   247   O O   . PRO A 1 44  ? -56.245  -21.467 60.868  1.00 61.01  ? 104 PRO A O   1 
ATOM   248   C CB  . PRO A 1 44  ? -55.315  -18.315 61.502  1.00 44.50  ? 104 PRO A CB  1 
ATOM   249   C CG  . PRO A 1 44  ? -54.501  -17.172 60.881  1.00 43.26  ? 104 PRO A CG  1 
ATOM   250   C CD  . PRO A 1 44  ? -53.999  -17.644 59.543  1.00 40.01  ? 104 PRO A CD  1 
ATOM   251   N N   . HIS A 1 45  ? -56.883  -19.889 59.367  1.00 53.73  ? 105 HIS A N   1 
ATOM   252   C CA  . HIS A 1 45  ? -58.139  -20.525 58.880  1.00 54.51  ? 105 HIS A CA  1 
ATOM   253   C C   . HIS A 1 45  ? -57.917  -22.028 58.617  1.00 56.94  ? 105 HIS A C   1 
ATOM   254   O O   . HIS A 1 45  ? -58.804  -22.823 58.988  1.00 60.64  ? 105 HIS A O   1 
ATOM   255   C CB  . HIS A 1 45  ? -58.683  -19.751 57.682  1.00 64.29  ? 105 HIS A CB  1 
ATOM   256   C CG  . HIS A 1 45  ? -60.057  -20.160 57.235  1.00 81.36  ? 105 HIS A CG  1 
ATOM   257   N ND1 . HIS A 1 45  ? -60.320  -21.445 56.754  1.00 75.68  ? 105 HIS A ND1 1 
ATOM   258   C CD2 . HIS A 1 45  ? -61.215  -19.463 57.116  1.00 96.09  ? 105 HIS A CD2 1 
ATOM   259   C CE1 . HIS A 1 45  ? -61.589  -21.520 56.390  1.00 78.17  ? 105 HIS A CE1 1 
ATOM   260   N NE2 . HIS A 1 45  ? -62.159  -20.322 56.609  1.00 95.25  ? 105 HIS A NE2 1 
ATOM   261   N N   . HIS A 1 46  ? -56.790  -22.438 58.036  1.00 55.99  ? 106 HIS A N   1 
ATOM   262   C CA  . HIS A 1 46  ? -56.547  -23.860 57.671  1.00 54.60  ? 106 HIS A CA  1 
ATOM   263   C C   . HIS A 1 46  ? -55.571  -24.548 58.630  1.00 56.42  ? 106 HIS A C   1 
ATOM   264   O O   . HIS A 1 46  ? -55.661  -25.774 58.751  1.00 70.14  ? 106 HIS A O   1 
ATOM   265   C CB  . HIS A 1 46  ? -56.060  -23.972 56.229  1.00 57.44  ? 106 HIS A CB  1 
ATOM   266   C CG  . HIS A 1 46  ? -57.067  -23.504 55.248  1.00 56.87  ? 106 HIS A CG  1 
ATOM   267   N ND1 . HIS A 1 46  ? -56.844  -22.415 54.433  1.00 64.60  ? 106 HIS A ND1 1 
ATOM   268   C CD2 . HIS A 1 46  ? -58.303  -23.955 54.968  1.00 57.93  ? 106 HIS A CD2 1 
ATOM   269   C CE1 . HIS A 1 46  ? -57.910  -22.207 53.687  1.00 62.29  ? 106 HIS A CE1 1 
ATOM   270   N NE2 . HIS A 1 46  ? -58.808  -23.147 53.986  1.00 64.19  ? 106 HIS A NE2 1 
ATOM   271   N N   . ASN A 1 47  ? -54.659  -23.815 59.270  1.00 52.52  ? 107 ASN A N   1 
ATOM   272   C CA  . ASN A 1 47  ? -53.495  -24.452 59.926  1.00 53.58  ? 107 ASN A CA  1 
ATOM   273   C C   . ASN A 1 47  ? -53.978  -25.449 60.982  1.00 54.71  ? 107 ASN A C   1 
ATOM   274   O O   . ASN A 1 47  ? -54.620  -25.016 61.948  1.00 67.28  ? 107 ASN A O   1 
ATOM   275   C CB  . ASN A 1 47  ? -52.534  -23.455 60.557  1.00 51.54  ? 107 ASN A CB  1 
ATOM   276   C CG  . ASN A 1 47  ? -51.614  -24.149 61.548  1.00 49.03  ? 107 ASN A CG  1 
ATOM   277   O OD1 . ASN A 1 47  ? -50.876  -25.053 61.181  1.00 43.58  ? 107 ASN A OD1 1 
ATOM   278   N ND2 . ASN A 1 47  ? -51.715  -23.805 62.817  1.00 48.52  ? 107 ASN A ND2 1 
ATOM   279   N N   . LYS A 1 48  ? -53.608  -26.720 60.834  1.00 51.67  ? 108 LYS A N   1 
ATOM   280   C CA  . LYS A 1 48  ? -53.931  -27.786 61.812  1.00 53.10  ? 108 LYS A CA  1 
ATOM   281   C C   . LYS A 1 48  ? -52.732  -28.121 62.701  1.00 46.14  ? 108 LYS A C   1 
ATOM   282   O O   . LYS A 1 48  ? -52.884  -29.030 63.496  1.00 49.69  ? 108 LYS A O   1 
ATOM   283   C CB  . LYS A 1 48  ? -54.416  -29.045 61.092  1.00 52.96  ? 108 LYS A CB  1 
ATOM   284   C CG  . LYS A 1 48  ? -55.648  -28.848 60.216  1.00 56.61  ? 108 LYS A CG  1 
ATOM   285   C CD  . LYS A 1 48  ? -56.099  -30.096 59.463  1.00 61.82  ? 108 LYS A CD  1 
ATOM   286   C CE  . LYS A 1 48  ? -56.180  -31.338 60.333  1.00 61.38  ? 108 LYS A CE  1 
ATOM   287   N NZ  . LYS A 1 48  ? -56.539  -32.536 59.532  1.00 65.92  ? 108 LYS A NZ  1 
ATOM   288   N N   . GLY A 1 49  ? -51.598  -27.432 62.611  1.00 40.63  ? 109 GLY A N   1 
ATOM   289   C CA  . GLY A 1 49  ? -50.408  -27.806 63.405  1.00 43.07  ? 109 GLY A CA  1 
ATOM   290   C C   . GLY A 1 49  ? -50.178  -29.307 63.334  1.00 43.43  ? 109 GLY A C   1 
ATOM   291   O O   . GLY A 1 49  ? -50.487  -29.908 62.268  1.00 39.38  ? 109 GLY A O   1 
ATOM   292   N N   . LEU A 1 50  ? -49.741  -29.937 64.429  1.00 44.50  ? 110 LEU A N   1 
ATOM   293   C CA  . LEU A 1 50  ? -49.374  -31.388 64.436  1.00 48.31  ? 110 LEU A CA  1 
ATOM   294   C C   . LEU A 1 50  ? -50.564  -32.299 64.095  1.00 53.52  ? 110 LEU A C   1 
ATOM   295   O O   . LEU A 1 50  ? -50.330  -33.517 64.036  1.00 50.97  ? 110 LEU A O   1 
ATOM   296   C CB  . LEU A 1 50  ? -48.835  -31.813 65.800  1.00 42.89  ? 110 LEU A CB  1 
ATOM   297   C CG  . LEU A 1 50  ? -47.609  -31.073 66.288  1.00 42.54  ? 110 LEU A CG  1 
ATOM   298   C CD1 . LEU A 1 50  ? -47.218  -31.596 67.648  1.00 46.11  ? 110 LEU A CD1 1 
ATOM   299   C CD2 . LEU A 1 50  ? -46.469  -31.235 65.308  1.00 42.91  ? 110 LEU A CD2 1 
ATOM   300   N N   . ALA A 1 51  ? -51.772  -31.756 63.932  1.00 46.70  ? 111 ALA A N   1 
ATOM   301   C CA  . ALA A 1 51  ? -52.995  -32.538 63.689  1.00 50.13  ? 111 ALA A CA  1 
ATOM   302   C C   . ALA A 1 51  ? -53.091  -32.846 62.203  1.00 53.83  ? 111 ALA A C   1 
ATOM   303   O O   . ALA A 1 51  ? -53.891  -33.757 61.865  1.00 67.20  ? 111 ALA A O   1 
ATOM   304   C CB  . ALA A 1 51  ? -54.223  -31.826 64.220  1.00 58.04  ? 111 ALA A CB  1 
ATOM   305   N N   . PHE A 1 52  ? -52.296  -32.162 61.361  1.00 54.39  ? 112 PHE A N   1 
ATOM   306   C CA  . PHE A 1 52  ? -52.093  -32.543 59.929  1.00 51.22  ? 112 PHE A CA  1 
ATOM   307   C C   . PHE A 1 52  ? -51.702  -34.015 59.835  1.00 50.60  ? 112 PHE A C   1 
ATOM   308   O O   . PHE A 1 52  ? -50.655  -34.406 60.394  1.00 55.00  ? 112 PHE A O   1 
ATOM   309   C CB  . PHE A 1 52  ? -51.012  -31.701 59.253  1.00 46.94  ? 112 PHE A CB  1 
ATOM   310   C CG  . PHE A 1 52  ? -51.524  -30.402 58.713  1.00 44.26  ? 112 PHE A CG  1 
ATOM   311   C CD1 . PHE A 1 52  ? -52.514  -30.414 57.751  1.00 47.92  ? 112 PHE A CD1 1 
ATOM   312   C CD2 . PHE A 1 52  ? -51.049  -29.185 59.179  1.00 44.66  ? 112 PHE A CD2 1 
ATOM   313   C CE1 . PHE A 1 52  ? -53.023  -29.229 57.242  1.00 54.48  ? 112 PHE A CE1 1 
ATOM   314   C CE2 . PHE A 1 52  ? -51.562  -27.995 58.679  1.00 48.21  ? 112 PHE A CE2 1 
ATOM   315   C CZ  . PHE A 1 52  ? -52.555  -28.014 57.710  1.00 50.76  ? 112 PHE A CZ  1 
ATOM   316   N N   . THR A 1 53  ? -52.531  -34.818 59.176  1.00 52.72  ? 113 THR A N   1 
ATOM   317   C CA  . THR A 1 53  ? -52.306  -36.277 59.019  1.00 59.61  ? 113 THR A CA  1 
ATOM   318   C C   . THR A 1 53  ? -51.065  -36.473 58.144  1.00 66.49  ? 113 THR A C   1 
ATOM   319   O O   . THR A 1 53  ? -50.727  -35.537 57.368  1.00 66.21  ? 113 THR A O   1 
ATOM   320   C CB  . THR A 1 53  ? -53.541  -36.967 58.423  1.00 61.96  ? 113 THR A CB  1 
ATOM   321   O OG1 . THR A 1 53  ? -53.779  -36.513 57.084  1.00 46.56  ? 113 THR A OG1 1 
ATOM   322   C CG2 . THR A 1 53  ? -54.782  -36.751 59.265  1.00 69.68  ? 113 THR A CG2 1 
ATOM   323   N N   . GLU A 1 54  ? -50.431  -37.644 58.268  1.00 71.01  ? 114 GLU A N   1 
ATOM   324   C CA  . GLU A 1 54  ? -49.245  -38.049 57.464  1.00 73.05  ? 114 GLU A CA  1 
ATOM   325   C C   . GLU A 1 54  ? -49.487  -37.702 55.984  1.00 68.37  ? 114 GLU A C   1 
ATOM   326   O O   . GLU A 1 54  ? -48.662  -36.992 55.378  1.00 64.67  ? 114 GLU A O   1 
ATOM   327   C CB  . GLU A 1 54  ? -49.003  -39.540 57.692  1.00 83.06  ? 114 GLU A CB  1 
ATOM   328   C CG  . GLU A 1 54  ? -47.542  -39.936 57.633  1.00 93.92  ? 114 GLU A CG  1 
ATOM   329   C CD  . GLU A 1 54  ? -47.298  -41.332 58.176  1.00 101.23 ? 114 GLU A CD  1 
ATOM   330   O OE1 . GLU A 1 54  ? -46.120  -41.778 58.197  1.00 102.81 ? 114 GLU A OE1 1 
ATOM   331   O OE2 . GLU A 1 54  ? -48.293  -41.988 58.563  1.00 115.91 ? 114 GLU A OE2 1 
ATOM   332   N N   . GLU A 1 55  ? -50.634  -38.146 55.461  1.00 77.51  ? 115 GLU A N   1 
ATOM   333   C CA  . GLU A 1 55  ? -51.084  -38.058 54.041  1.00 68.53  ? 115 GLU A CA  1 
ATOM   334   C C   . GLU A 1 55  ? -51.173  -36.581 53.646  1.00 60.69  ? 115 GLU A C   1 
ATOM   335   O O   . GLU A 1 55  ? -50.733  -36.239 52.554  1.00 56.35  ? 115 GLU A O   1 
ATOM   336   C CB  . GLU A 1 55  ? -52.424  -38.788 53.869  1.00 80.31  ? 115 GLU A CB  1 
ATOM   337   C CG  . GLU A 1 55  ? -52.442  -40.234 54.413  1.00 95.39  ? 115 GLU A CG  1 
ATOM   338   C CD  . GLU A 1 55  ? -52.887  -40.530 55.862  1.00 103.63 ? 115 GLU A CD  1 
ATOM   339   O OE1 . GLU A 1 55  ? -53.562  -39.693 56.516  1.00 88.58  ? 115 GLU A OE1 1 
ATOM   340   O OE2 . GLU A 1 55  ? -52.532  -41.612 56.358  1.00 113.44 ? 115 GLU A OE2 1 
ATOM   341   N N   . GLU A 1 56  ? -51.692  -35.731 54.529  1.00 61.82  ? 116 GLU A N   1 
ATOM   342   C CA  . GLU A 1 56  ? -51.856  -34.270 54.291  1.00 66.19  ? 116 GLU A CA  1 
ATOM   343   C C   . GLU A 1 56  ? -50.500  -33.575 54.191  1.00 63.68  ? 116 GLU A C   1 
ATOM   344   O O   . GLU A 1 56  ? -50.419  -32.609 53.401  1.00 71.22  ? 116 GLU A O   1 
ATOM   345   C CB  . GLU A 1 56  ? -52.648  -33.611 55.426  1.00 71.98  ? 116 GLU A CB  1 
ATOM   346   C CG  . GLU A 1 56  ? -54.118  -33.996 55.422  1.00 74.25  ? 116 GLU A CG  1 
ATOM   347   C CD  . GLU A 1 56  ? -54.942  -33.528 56.603  1.00 68.90  ? 116 GLU A CD  1 
ATOM   348   O OE1 . GLU A 1 56  ? -54.359  -33.290 57.665  1.00 74.60  ? 116 GLU A OE1 1 
ATOM   349   O OE2 . GLU A 1 56  ? -56.159  -33.411 56.458  1.00 74.02  ? 116 GLU A OE2 1 
ATOM   350   N N   . ARG A 1 57  ? -49.518  -34.026 54.983  1.00 58.15  ? 117 ARG A N   1 
ATOM   351   C CA  . ARG A 1 57  ? -48.147  -33.454 55.052  1.00 60.12  ? 117 ARG A CA  1 
ATOM   352   C C   . ARG A 1 57  ? -47.376  -33.752 53.750  1.00 65.05  ? 117 ARG A C   1 
ATOM   353   O O   . ARG A 1 57  ? -46.785  -32.777 53.151  1.00 66.21  ? 117 ARG A O   1 
ATOM   354   C CB  . ARG A 1 57  ? -47.377  -34.017 56.249  1.00 59.91  ? 117 ARG A CB  1 
ATOM   355   C CG  . ARG A 1 57  ? -48.058  -33.809 57.600  1.00 64.46  ? 117 ARG A CG  1 
ATOM   356   C CD  . ARG A 1 57  ? -47.173  -34.128 58.807  1.00 56.73  ? 117 ARG A CD  1 
ATOM   357   N NE  . ARG A 1 57  ? -47.867  -33.960 60.072  1.00 52.93  ? 117 ARG A NE  1 
ATOM   358   C CZ  . ARG A 1 57  ? -47.315  -34.115 61.275  1.00 54.78  ? 117 ARG A CZ  1 
ATOM   359   N NH1 . ARG A 1 57  ? -46.041  -34.430 61.371  1.00 52.45  ? 117 ARG A NH1 1 
ATOM   360   N NH2 . ARG A 1 57  ? -48.036  -33.963 62.380  1.00 52.45  ? 117 ARG A NH2 1 
ATOM   361   N N   . ASP A 1 58  ? -47.374  -35.025 53.309  1.00 56.00  ? 118 ASP A N   1 
ATOM   362   C CA  . ASP A 1 58  ? -46.801  -35.446 52.002  1.00 55.45  ? 118 ASP A CA  1 
ATOM   363   C C   . ASP A 1 58  ? -47.428  -34.586 50.904  1.00 54.60  ? 118 ASP A C   1 
ATOM   364   O O   . ASP A 1 58  ? -46.688  -33.964 50.109  1.00 54.15  ? 118 ASP A O   1 
ATOM   365   C CB  . ASP A 1 58  ? -47.030  -36.934 51.735  1.00 57.29  ? 118 ASP A CB  1 
ATOM   366   C CG  . ASP A 1 58  ? -46.317  -37.839 52.723  1.00 64.36  ? 118 ASP A CG  1 
ATOM   367   O OD1 . ASP A 1 58  ? -45.514  -37.284 53.546  1.00 64.75  ? 118 ASP A OD1 1 
ATOM   368   O OD2 . ASP A 1 58  ? -46.532  -39.091 52.660  1.00 60.23  ? 118 ASP A OD2 1 
ATOM   369   N N   . GLY A 1 59  ? -48.755  -34.514 50.933  1.00 55.48  ? 119 GLY A N   1 
ATOM   370   C CA  . GLY A 1 59  ? -49.582  -33.797 49.961  1.00 54.47  ? 119 GLY A CA  1 
ATOM   371   C C   . GLY A 1 59  ? -49.216  -32.335 49.857  1.00 55.24  ? 119 GLY A C   1 
ATOM   372   O O   . GLY A 1 59  ? -49.291  -31.825 48.734  1.00 64.07  ? 119 GLY A O   1 
ATOM   373   N N   . HIS A 1 60  ? -48.876  -31.653 50.956  1.00 52.54  ? 120 HIS A N   1 
ATOM   374   C CA  . HIS A 1 60  ? -48.807  -30.160 50.963  1.00 52.23  ? 120 HIS A CA  1 
ATOM   375   C C   . HIS A 1 60  ? -47.431  -29.656 51.388  1.00 55.16  ? 120 HIS A C   1 
ATOM   376   O O   . HIS A 1 60  ? -47.355  -28.487 51.851  1.00 55.39  ? 120 HIS A O   1 
ATOM   377   C CB  . HIS A 1 60  ? -49.900  -29.556 51.835  1.00 48.45  ? 120 HIS A CB  1 
ATOM   378   C CG  . HIS A 1 60  ? -51.259  -29.759 51.272  1.00 55.82  ? 120 HIS A CG  1 
ATOM   379   N ND1 . HIS A 1 60  ? -51.781  -28.960 50.262  1.00 58.02  ? 120 HIS A ND1 1 
ATOM   380   C CD2 . HIS A 1 60  ? -52.203  -30.672 51.568  1.00 58.56  ? 120 HIS A CD2 1 
ATOM   381   C CE1 . HIS A 1 60  ? -52.994  -29.374 49.970  1.00 58.45  ? 120 HIS A CE1 1 
ATOM   382   N NE2 . HIS A 1 60  ? -53.275  -30.421 50.751  1.00 63.43  ? 120 HIS A NE2 1 
ATOM   383   N N   . TYR A 1 61  ? -46.397  -30.482 51.212  1.00 52.51  ? 121 TYR A N   1 
ATOM   384   C CA  . TYR A 1 61  ? -44.994  -30.067 51.411  1.00 59.38  ? 121 TYR A CA  1 
ATOM   385   C C   . TYR A 1 61  ? -44.818  -29.553 52.849  1.00 56.40  ? 121 TYR A C   1 
ATOM   386   O O   . TYR A 1 61  ? -44.226  -28.476 53.081  1.00 56.45  ? 121 TYR A O   1 
ATOM   387   C CB  . TYR A 1 61  ? -44.631  -29.033 50.348  1.00 61.12  ? 121 TYR A CB  1 
ATOM   388   C CG  . TYR A 1 61  ? -44.999  -29.445 48.945  1.00 65.34  ? 121 TYR A CG  1 
ATOM   389   C CD1 . TYR A 1 61  ? -44.430  -30.569 48.365  1.00 78.10  ? 121 TYR A CD1 1 
ATOM   390   C CD2 . TYR A 1 61  ? -45.926  -28.735 48.201  1.00 61.94  ? 121 TYR A CD2 1 
ATOM   391   C CE1 . TYR A 1 61  ? -44.760  -30.970 47.076  1.00 67.49  ? 121 TYR A CE1 1 
ATOM   392   C CE2 . TYR A 1 61  ? -46.276  -29.120 46.917  1.00 57.37  ? 121 TYR A CE2 1 
ATOM   393   C CZ  . TYR A 1 61  ? -45.687  -30.239 46.357  1.00 65.01  ? 121 TYR A CZ  1 
ATOM   394   O OH  . TYR A 1 61  ? -46.005  -30.635 45.095  1.00 84.21  ? 121 TYR A OH  1 
ATOM   395   N N   . LEU A 1 62  ? -45.329  -30.333 53.796  1.00 50.92  ? 122 LEU A N   1 
ATOM   396   C CA  . LEU A 1 62  ? -45.108  -30.130 55.241  1.00 53.99  ? 122 LEU A CA  1 
ATOM   397   C C   . LEU A 1 62  ? -44.043  -31.110 55.732  1.00 52.99  ? 122 LEU A C   1 
ATOM   398   O O   . LEU A 1 62  ? -43.374  -30.767 56.720  1.00 50.17  ? 122 LEU A O   1 
ATOM   399   C CB  . LEU A 1 62  ? -46.422  -30.354 55.988  1.00 58.30  ? 122 LEU A CB  1 
ATOM   400   C CG  . LEU A 1 62  ? -47.582  -29.463 55.541  1.00 61.25  ? 122 LEU A CG  1 
ATOM   401   C CD1 . LEU A 1 62  ? -48.822  -29.712 56.410  1.00 61.89  ? 122 LEU A CD1 1 
ATOM   402   C CD2 . LEU A 1 62  ? -47.175  -27.990 55.559  1.00 52.80  ? 122 LEU A CD2 1 
ATOM   403   N N   . ARG A 1 63  ? -43.889  -32.271 55.082  1.00 57.32  ? 123 ARG A N   1 
ATOM   404   C CA  . ARG A 1 63  ? -42.929  -33.318 55.529  1.00 59.66  ? 123 ARG A CA  1 
ATOM   405   C C   . ARG A 1 63  ? -41.611  -32.612 55.877  1.00 63.38  ? 123 ARG A C   1 
ATOM   406   O O   . ARG A 1 63  ? -41.115  -31.862 55.027  1.00 56.66  ? 123 ARG A O   1 
ATOM   407   C CB  . ARG A 1 63  ? -42.782  -34.430 54.488  1.00 50.73  ? 123 ARG A CB  1 
ATOM   408   C CG  . ARG A 1 63  ? -42.054  -35.643 55.028  1.00 51.15  ? 123 ARG A CG  1 
ATOM   409   C CD  . ARG A 1 63  ? -41.340  -36.407 53.928  1.00 68.44  ? 123 ARG A CD  1 
ATOM   410   N NE  . ARG A 1 63  ? -42.046  -37.509 53.257  1.00 77.13  ? 123 ARG A NE  1 
ATOM   411   C CZ  . ARG A 1 63  ? -42.065  -38.786 53.671  1.00 81.26  ? 123 ARG A CZ  1 
ATOM   412   N NH1 . ARG A 1 63  ? -41.495  -39.140 54.808  1.00 83.89  ? 123 ARG A NH1 1 
ATOM   413   N NH2 . ARG A 1 63  ? -42.729  -39.696 52.987  1.00 89.82  ? 123 ARG A NH2 1 
ATOM   414   N N   . GLY A 1 64  ? -41.141  -32.759 57.124  1.00 62.08  ? 124 GLY A N   1 
ATOM   415   C CA  . GLY A 1 64  ? -39.920  -32.104 57.618  1.00 56.82  ? 124 GLY A CA  1 
ATOM   416   C C   . GLY A 1 64  ? -40.195  -30.835 58.421  1.00 52.32  ? 124 GLY A C   1 
ATOM   417   O O   . GLY A 1 64  ? -39.498  -30.605 59.426  1.00 42.30  ? 124 GLY A O   1 
ATOM   418   N N   . LEU A 1 65  ? -41.136  -30.003 57.984  1.00 52.22  ? 125 LEU A N   1 
ATOM   419   C CA  . LEU A 1 65  ? -41.451  -28.706 58.649  1.00 55.33  ? 125 LEU A CA  1 
ATOM   420   C C   . LEU A 1 65  ? -42.171  -28.955 59.979  1.00 51.00  ? 125 LEU A C   1 
ATOM   421   O O   . LEU A 1 65  ? -42.212  -28.056 60.814  1.00 56.71  ? 125 LEU A O   1 
ATOM   422   C CB  . LEU A 1 65  ? -42.328  -27.858 57.720  1.00 59.44  ? 125 LEU A CB  1 
ATOM   423   C CG  . LEU A 1 65  ? -41.747  -27.528 56.345  1.00 56.21  ? 125 LEU A CG  1 
ATOM   424   C CD1 . LEU A 1 65  ? -42.731  -26.675 55.561  1.00 60.37  ? 125 LEU A CD1 1 
ATOM   425   C CD2 . LEU A 1 65  ? -40.387  -26.864 56.479  1.00 55.44  ? 125 LEU A CD2 1 
ATOM   426   N N   . LEU A 1 66  ? -42.796  -30.117 60.133  1.00 52.52  ? 126 LEU A N   1 
ATOM   427   C CA  . LEU A 1 66  ? -43.402  -30.609 61.399  1.00 49.78  ? 126 LEU A CA  1 
ATOM   428   C C   . LEU A 1 66  ? -42.596  -31.801 61.890  1.00 49.40  ? 126 LEU A C   1 
ATOM   429   O O   . LEU A 1 66  ? -42.051  -32.583 61.106  1.00 51.41  ? 126 LEU A O   1 
ATOM   430   C CB  . LEU A 1 66  ? -44.849  -31.045 61.160  1.00 45.26  ? 126 LEU A CB  1 
ATOM   431   C CG  . LEU A 1 66  ? -45.778  -29.979 60.591  1.00 47.29  ? 126 LEU A CG  1 
ATOM   432   C CD1 . LEU A 1 66  ? -47.190  -30.574 60.450  1.00 43.56  ? 126 LEU A CD1 1 
ATOM   433   C CD2 . LEU A 1 66  ? -45.780  -28.698 61.441  1.00 45.57  ? 126 LEU A CD2 1 
ATOM   434   N N   . PRO A 1 67  ? -42.541  -32.004 63.213  1.00 53.17  ? 127 PRO A N   1 
ATOM   435   C CA  . PRO A 1 67  ? -41.958  -33.232 63.751  1.00 60.54  ? 127 PRO A CA  1 
ATOM   436   C C   . PRO A 1 67  ? -42.770  -34.439 63.292  1.00 56.13  ? 127 PRO A C   1 
ATOM   437   O O   . PRO A 1 67  ? -43.895  -34.276 62.864  1.00 55.98  ? 127 PRO A O   1 
ATOM   438   C CB  . PRO A 1 67  ? -42.068  -33.084 65.270  1.00 63.41  ? 127 PRO A CB  1 
ATOM   439   C CG  . PRO A 1 67  ? -42.524  -31.653 65.528  1.00 56.42  ? 127 PRO A CG  1 
ATOM   440   C CD  . PRO A 1 67  ? -43.042  -31.071 64.231  1.00 54.63  ? 127 PRO A CD  1 
ATOM   441   N N   . PRO A 1 68  ? -42.252  -35.682 63.363  1.00 60.06  ? 128 PRO A N   1 
ATOM   442   C CA  . PRO A 1 68  ? -42.986  -36.854 62.857  1.00 68.94  ? 128 PRO A CA  1 
ATOM   443   C C   . PRO A 1 68  ? -44.369  -37.142 63.484  1.00 59.52  ? 128 PRO A C   1 
ATOM   444   O O   . PRO A 1 68  ? -45.219  -37.653 62.801  1.00 55.21  ? 128 PRO A O   1 
ATOM   445   C CB  . PRO A 1 68  ? -42.067  -38.046 63.163  1.00 73.56  ? 128 PRO A CB  1 
ATOM   446   C CG  . PRO A 1 68  ? -40.701  -37.419 63.359  1.00 77.47  ? 128 PRO A CG  1 
ATOM   447   C CD  . PRO A 1 68  ? -40.924  -36.008 63.888  1.00 67.79  ? 128 PRO A CD  1 
ATOM   448   N N   . ALA A 1 69  ? -44.566  -36.794 64.753  1.00 53.76  ? 129 ALA A N   1 
ATOM   449   C CA  . ALA A 1 69  ? -45.773  -37.097 65.560  1.00 56.16  ? 129 ALA A CA  1 
ATOM   450   C C   . ALA A 1 69  ? -47.008  -36.366 65.021  1.00 58.78  ? 129 ALA A C   1 
ATOM   451   O O   . ALA A 1 69  ? -46.972  -35.120 64.855  1.00 61.62  ? 129 ALA A O   1 
ATOM   452   C CB  . ALA A 1 69  ? -45.544  -36.735 67.011  1.00 58.99  ? 129 ALA A CB  1 
ATOM   453   N N   . VAL A 1 70  ? -48.087  -37.129 64.848  1.00 58.37  ? 130 VAL A N   1 
ATOM   454   C CA  . VAL A 1 70  ? -49.455  -36.632 64.534  1.00 52.15  ? 130 VAL A CA  1 
ATOM   455   C C   . VAL A 1 70  ? -50.328  -36.668 65.798  1.00 53.87  ? 130 VAL A C   1 
ATOM   456   O O   . VAL A 1 70  ? -50.610  -37.760 66.308  1.00 51.51  ? 130 VAL A O   1 
ATOM   457   C CB  . VAL A 1 70  ? -50.075  -37.433 63.375  1.00 44.83  ? 130 VAL A CB  1 
ATOM   458   C CG1 . VAL A 1 70  ? -51.442  -36.888 62.999  1.00 46.90  ? 130 VAL A CG1 1 
ATOM   459   C CG2 . VAL A 1 70  ? -49.174  -37.421 62.150  1.00 43.87  ? 130 VAL A CG2 1 
ATOM   460   N N   . LEU A 1 71  ? -50.747  -35.492 66.268  1.00 56.28  ? 131 LEU A N   1 
ATOM   461   C CA  . LEU A 1 71  ? -51.766  -35.309 67.342  1.00 56.87  ? 131 LEU A CA  1 
ATOM   462   C C   . LEU A 1 71  ? -53.186  -35.302 66.756  1.00 57.41  ? 131 LEU A C   1 
ATOM   463   O O   . LEU A 1 71  ? -53.365  -34.814 65.624  1.00 57.75  ? 131 LEU A O   1 
ATOM   464   C CB  . LEU A 1 71  ? -51.522  -33.974 68.046  1.00 57.95  ? 131 LEU A CB  1 
ATOM   465   C CG  . LEU A 1 71  ? -50.393  -34.000 69.069  1.00 58.52  ? 131 LEU A CG  1 
ATOM   466   C CD1 . LEU A 1 71  ? -50.196  -32.639 69.727  1.00 54.93  ? 131 LEU A CD1 1 
ATOM   467   C CD2 . LEU A 1 71  ? -50.678  -35.078 70.094  1.00 58.42  ? 131 LEU A CD2 1 
ATOM   468   N N   . SER A 1 72  ? -54.165  -35.783 67.524  1.00 58.13  ? 132 SER A N   1 
ATOM   469   C CA  . SER A 1 72  ? -55.611  -35.456 67.358  1.00 56.18  ? 132 SER A CA  1 
ATOM   470   C C   . SER A 1 72  ? -55.901  -34.004 67.803  1.00 54.68  ? 132 SER A C   1 
ATOM   471   O O   . SER A 1 72  ? -55.058  -33.374 68.494  1.00 46.03  ? 132 SER A O   1 
ATOM   472   C CB  . SER A 1 72  ? -56.453  -36.406 68.139  1.00 54.78  ? 132 SER A CB  1 
ATOM   473   O OG  . SER A 1 72  ? -56.305  -36.153 69.538  1.00 56.88  ? 132 SER A OG  1 
ATOM   474   N N   . GLN A 1 73  ? -57.074  -33.488 67.450  1.00 53.28  ? 133 GLN A N   1 
ATOM   475   C CA  . GLN A 1 73  ? -57.535  -32.157 67.909  1.00 56.98  ? 133 GLN A CA  1 
ATOM   476   C C   . GLN A 1 73  ? -57.723  -32.218 69.429  1.00 62.56  ? 133 GLN A C   1 
ATOM   477   O O   . GLN A 1 73  ? -57.485  -31.196 70.086  1.00 50.67  ? 133 GLN A O   1 
ATOM   478   C CB  . GLN A 1 73  ? -58.808  -31.757 67.155  1.00 57.14  ? 133 GLN A CB  1 
ATOM   479   C CG  . GLN A 1 73  ? -59.123  -30.270 67.261  1.00 53.71  ? 133 GLN A CG  1 
ATOM   480   C CD  . GLN A 1 73  ? -60.313  -29.864 66.433  1.00 48.96  ? 133 GLN A CD  1 
ATOM   481   O OE1 . GLN A 1 73  ? -61.027  -30.708 65.906  1.00 45.76  ? 133 GLN A OE1 1 
ATOM   482   N NE2 . GLN A 1 73  ? -60.521  -28.565 66.306  1.00 44.06  ? 133 GLN A NE2 1 
ATOM   483   N N   . GLU A 1 74  ? -58.122  -33.387 69.965  1.00 74.56  ? 134 GLU A N   1 
ATOM   484   C CA  . GLU A 1 74  ? -58.487  -33.578 71.399  1.00 77.34  ? 134 GLU A CA  1 
ATOM   485   C C   . GLU A 1 74  ? -57.224  -33.494 72.249  1.00 72.74  ? 134 GLU A C   1 
ATOM   486   O O   . GLU A 1 74  ? -57.254  -32.795 73.291  1.00 79.58  ? 134 GLU A O   1 
ATOM   487   C CB  . GLU A 1 74  ? -59.207  -34.908 71.614  1.00 95.11  ? 134 GLU A CB  1 
ATOM   488   C CG  . GLU A 1 74  ? -60.699  -34.819 71.281  1.00 116.92 ? 134 GLU A CG  1 
ATOM   489   C CD  . GLU A 1 74  ? -61.598  -35.971 71.733  1.00 126.82 ? 134 GLU A CD  1 
ATOM   490   O OE1 . GLU A 1 74  ? -61.194  -37.155 71.606  1.00 118.98 ? 134 GLU A OE1 1 
ATOM   491   O OE2 . GLU A 1 74  ? -62.725  -35.689 72.198  1.00 120.45 ? 134 GLU A OE2 1 
ATOM   492   N N   . LEU A 1 75  ? -56.179  -34.202 71.824  1.00 57.18  ? 135 LEU A N   1 
ATOM   493   C CA  . LEU A 1 75  ? -54.839  -34.136 72.447  1.00 51.37  ? 135 LEU A CA  1 
ATOM   494   C C   . LEU A 1 75  ? -54.363  -32.689 72.390  1.00 47.56  ? 135 LEU A C   1 
ATOM   495   O O   . LEU A 1 75  ? -53.824  -32.221 73.382  1.00 51.15  ? 135 LEU A O   1 
ATOM   496   C CB  . LEU A 1 75  ? -53.868  -35.056 71.699  1.00 60.03  ? 135 LEU A CB  1 
ATOM   497   C CG  . LEU A 1 75  ? -53.598  -36.429 72.305  1.00 61.50  ? 135 LEU A CG  1 
ATOM   498   C CD1 . LEU A 1 75  ? -52.797  -36.283 73.587  1.00 67.43  ? 135 LEU A CD1 1 
ATOM   499   C CD2 . LEU A 1 75  ? -54.889  -37.189 72.557  1.00 63.39  ? 135 LEU A CD2 1 
ATOM   500   N N   . GLN A 1 76  ? -54.557  -32.005 71.259  1.00 51.41  ? 136 GLN A N   1 
ATOM   501   C CA  . GLN A 1 76  ? -54.180  -30.572 71.097  1.00 51.24  ? 136 GLN A CA  1 
ATOM   502   C C   . GLN A 1 76  ? -54.826  -29.755 72.225  1.00 55.37  ? 136 GLN A C   1 
ATOM   503   O O   . GLN A 1 76  ? -54.115  -28.927 72.849  1.00 65.43  ? 136 GLN A O   1 
ATOM   504   C CB  . GLN A 1 76  ? -54.577  -30.015 69.722  1.00 52.34  ? 136 GLN A CB  1 
ATOM   505   C CG  . GLN A 1 76  ? -53.528  -30.208 68.634  1.00 52.97  ? 136 GLN A CG  1 
ATOM   506   C CD  . GLN A 1 76  ? -54.006  -29.811 67.256  1.00 51.93  ? 136 GLN A CD  1 
ATOM   507   O OE1 . GLN A 1 76  ? -55.202  -29.670 66.995  1.00 52.01  ? 136 GLN A OE1 1 
ATOM   508   N NE2 . GLN A 1 76  ? -53.062  -29.632 66.354  1.00 50.41  ? 136 GLN A NE2 1 
ATOM   509   N N   . ILE A 1 77  ? -56.122  -29.973 72.469  1.00 58.94  ? 137 ILE A N   1 
ATOM   510   C CA  . ILE A 1 77  ? -56.928  -29.204 73.468  1.00 62.05  ? 137 ILE A CA  1 
ATOM   511   C C   . ILE A 1 77  ? -56.318  -29.461 74.853  1.00 64.73  ? 137 ILE A C   1 
ATOM   512   O O   . ILE A 1 77  ? -56.023  -28.468 75.552  1.00 57.12  ? 137 ILE A O   1 
ATOM   513   C CB  . ILE A 1 77  ? -58.434  -29.537 73.357  1.00 59.73  ? 137 ILE A CB  1 
ATOM   514   C CG1 . ILE A 1 77  ? -58.981  -29.028 72.018  1.00 58.60  ? 137 ILE A CG1 1 
ATOM   515   C CG2 . ILE A 1 77  ? -59.223  -28.976 74.536  1.00 56.14  ? 137 ILE A CG2 1 
ATOM   516   C CD1 . ILE A 1 77  ? -60.437  -29.302 71.777  1.00 63.85  ? 137 ILE A CD1 1 
ATOM   517   N N   . LYS A 1 78  ? -56.094  -30.738 75.196  1.00 60.88  ? 138 LYS A N   1 
ATOM   518   C CA  . LYS A 1 78  ? -55.513  -31.179 76.490  1.00 54.84  ? 138 LYS A CA  1 
ATOM   519   C C   . LYS A 1 78  ? -54.190  -30.434 76.696  1.00 52.35  ? 138 LYS A C   1 
ATOM   520   O O   . LYS A 1 78  ? -53.980  -29.908 77.810  1.00 63.60  ? 138 LYS A O   1 
ATOM   521   C CB  . LYS A 1 78  ? -55.363  -32.709 76.511  1.00 59.42  ? 138 LYS A CB  1 
ATOM   522   C CG  . LYS A 1 78  ? -54.794  -33.277 77.796  1.00 61.64  ? 138 LYS A CG  1 
ATOM   523   C CD  . LYS A 1 78  ? -54.877  -34.753 77.910  1.00 70.07  ? 138 LYS A CD  1 
ATOM   524   C CE  . LYS A 1 78  ? -54.527  -35.222 79.317  1.00 81.34  ? 138 LYS A CE  1 
ATOM   525   N NZ  . LYS A 1 78  ? -53.928  -36.581 79.331  1.00 81.60  ? 138 LYS A NZ  1 
ATOM   526   N N   . LYS A 1 79  ? -53.353  -30.381 75.652  1.00 49.37  ? 139 LYS A N   1 
ATOM   527   C CA  . LYS A 1 79  ? -51.990  -29.798 75.665  1.00 45.86  ? 139 LYS A CA  1 
ATOM   528   C C   . LYS A 1 79  ? -52.087  -28.287 75.871  1.00 40.52  ? 139 LYS A C   1 
ATOM   529   O O   . LYS A 1 79  ? -51.370  -27.782 76.738  1.00 44.26  ? 139 LYS A O   1 
ATOM   530   C CB  . LYS A 1 79  ? -51.247  -30.116 74.368  1.00 49.54  ? 139 LYS A CB  1 
ATOM   531   C CG  . LYS A 1 79  ? -49.949  -29.340 74.176  1.00 54.47  ? 139 LYS A CG  1 
ATOM   532   C CD  . LYS A 1 79  ? -48.886  -30.052 73.400  1.00 56.49  ? 139 LYS A CD  1 
ATOM   533   C CE  . LYS A 1 79  ? -49.051  -29.953 71.910  1.00 60.34  ? 139 LYS A CE  1 
ATOM   534   N NZ  . LYS A 1 79  ? -47.970  -30.706 71.216  1.00 70.25  ? 139 LYS A NZ  1 
ATOM   535   N N   . PHE A 1 80  ? -52.902  -27.583 75.094  1.00 39.13  ? 140 PHE A N   1 
ATOM   536   C CA  . PHE A 1 80  ? -53.042  -26.114 75.248  1.00 46.13  ? 140 PHE A CA  1 
ATOM   537   C C   . PHE A 1 80  ? -53.608  -25.822 76.639  1.00 53.59  ? 140 PHE A C   1 
ATOM   538   O O   . PHE A 1 80  ? -53.129  -24.867 77.292  1.00 61.13  ? 140 PHE A O   1 
ATOM   539   C CB  . PHE A 1 80  ? -53.899  -25.458 74.165  1.00 44.62  ? 140 PHE A CB  1 
ATOM   540   C CG  . PHE A 1 80  ? -53.753  -23.954 74.126  1.00 45.21  ? 140 PHE A CG  1 
ATOM   541   C CD1 . PHE A 1 80  ? -54.629  -23.119 74.803  1.00 45.50  ? 140 PHE A CD1 1 
ATOM   542   C CD2 . PHE A 1 80  ? -52.692  -23.355 73.469  1.00 46.93  ? 140 PHE A CD2 1 
ATOM   543   C CE1 . PHE A 1 80  ? -54.481  -21.727 74.769  1.00 47.29  ? 140 PHE A CE1 1 
ATOM   544   C CE2 . PHE A 1 80  ? -52.538  -21.970 73.461  1.00 46.88  ? 140 PHE A CE2 1 
ATOM   545   C CZ  . PHE A 1 80  ? -53.430  -21.154 74.105  1.00 38.68  ? 140 PHE A CZ  1 
ATOM   546   N N   . MET A 1 81  ? -54.591  -26.608 77.087  1.00 54.96  ? 141 MET A N   1 
ATOM   547   C CA  . MET A 1 81  ? -55.257  -26.387 78.394  1.00 58.42  ? 141 MET A CA  1 
ATOM   548   C C   . MET A 1 81  ? -54.169  -26.478 79.471  1.00 58.80  ? 141 MET A C   1 
ATOM   549   O O   . MET A 1 81  ? -54.071  -25.559 80.277  1.00 66.79  ? 141 MET A O   1 
ATOM   550   C CB  . MET A 1 81  ? -56.408  -27.379 78.650  1.00 60.41  ? 141 MET A CB  1 
ATOM   551   C CG  . MET A 1 81  ? -57.778  -26.973 78.016  1.00 65.26  ? 141 MET A CG  1 
ATOM   552   S SD  . MET A 1 81  ? -58.296  -25.182 78.174  1.00 54.03  ? 141 MET A SD  1 
ATOM   553   C CE  . MET A 1 81  ? -58.799  -25.129 79.889  1.00 51.09  ? 141 MET A CE  1 
ATOM   554   N N   . ASN A 1 82  ? -53.318  -27.496 79.404  1.00 56.51  ? 142 ASN A N   1 
ATOM   555   C CA  . ASN A 1 82  ? -52.243  -27.742 80.402  1.00 59.68  ? 142 ASN A CA  1 
ATOM   556   C C   . ASN A 1 82  ? -51.358  -26.500 80.518  1.00 60.65  ? 142 ASN A C   1 
ATOM   557   O O   . ASN A 1 82  ? -51.165  -26.052 81.654  1.00 56.47  ? 142 ASN A O   1 
ATOM   558   C CB  . ASN A 1 82  ? -51.431  -28.994 80.069  1.00 70.35  ? 142 ASN A CB  1 
ATOM   559   C CG  . ASN A 1 82  ? -52.016  -30.268 80.631  1.00 80.35  ? 142 ASN A CG  1 
ATOM   560   O OD1 . ASN A 1 82  ? -52.867  -30.233 81.519  1.00 90.34  ? 142 ASN A OD1 1 
ATOM   561   N ND2 . ASN A 1 82  ? -51.582  -31.399 80.094  1.00 79.74  ? 142 ASN A ND2 1 
ATOM   562   N N   . THR A 1 83  ? -50.876  -25.944 79.395  1.00 72.33  ? 143 THR A N   1 
ATOM   563   C CA  . THR A 1 83  ? -49.970  -24.751 79.365  1.00 67.85  ? 143 THR A CA  1 
ATOM   564   C C   . THR A 1 83  ? -50.750  -23.457 79.650  1.00 55.44  ? 143 THR A C   1 
ATOM   565   O O   . THR A 1 83  ? -50.138  -22.479 80.071  1.00 50.09  ? 143 THR A O   1 
ATOM   566   C CB  . THR A 1 83  ? -49.162  -24.632 78.057  1.00 63.38  ? 143 THR A CB  1 
ATOM   567   O OG1 . THR A 1 83  ? -50.001  -24.736 76.917  1.00 60.20  ? 143 THR A OG1 1 
ATOM   568   C CG2 . THR A 1 83  ? -48.098  -25.688 77.915  1.00 65.07  ? 143 THR A CG2 1 
ATOM   569   N N   . LEU A 1 84  ? -52.055  -23.445 79.462  1.00 55.78  ? 144 LEU A N   1 
ATOM   570   C CA  . LEU A 1 84  ? -52.847  -22.226 79.741  1.00 56.78  ? 144 LEU A CA  1 
ATOM   571   C C   . LEU A 1 84  ? -52.953  -22.015 81.256  1.00 64.35  ? 144 LEU A C   1 
ATOM   572   O O   . LEU A 1 84  ? -52.960  -20.840 81.716  1.00 64.41  ? 144 LEU A O   1 
ATOM   573   C CB  . LEU A 1 84  ? -54.229  -22.362 79.111  1.00 46.81  ? 144 LEU A CB  1 
ATOM   574   C CG  . LEU A 1 84  ? -55.010  -21.057 79.131  1.00 47.69  ? 144 LEU A CG  1 
ATOM   575   C CD1 . LEU A 1 84  ? -54.267  -19.925 78.424  1.00 46.20  ? 144 LEU A CD1 1 
ATOM   576   C CD2 . LEU A 1 84  ? -56.357  -21.289 78.513  1.00 53.70  ? 144 LEU A CD2 1 
ATOM   577   N N   . ARG A 1 85  ? -53.029  -23.122 81.998  1.00 63.60  ? 145 ARG A N   1 
ATOM   578   C CA  . ARG A 1 85  ? -53.286  -23.129 83.455  1.00 59.14  ? 145 ARG A CA  1 
ATOM   579   C C   . ARG A 1 85  ? -51.988  -22.755 84.184  1.00 71.18  ? 145 ARG A C   1 
ATOM   580   O O   . ARG A 1 85  ? -52.065  -22.407 85.364  1.00 89.47  ? 145 ARG A O   1 
ATOM   581   C CB  . ARG A 1 85  ? -53.823  -24.492 83.901  1.00 58.07  ? 145 ARG A CB  1 
ATOM   582   C CG  . ARG A 1 85  ? -55.170  -24.858 83.295  1.00 60.36  ? 145 ARG A CG  1 
ATOM   583   C CD  . ARG A 1 85  ? -55.609  -26.254 83.688  1.00 65.91  ? 145 ARG A CD  1 
ATOM   584   N NE  . ARG A 1 85  ? -57.039  -26.497 83.577  1.00 74.28  ? 145 ARG A NE  1 
ATOM   585   C CZ  . ARG A 1 85  ? -57.613  -27.414 82.800  1.00 70.27  ? 145 ARG A CZ  1 
ATOM   586   N NH1 . ARG A 1 85  ? -56.891  -28.174 82.010  1.00 82.14  ? 145 ARG A NH1 1 
ATOM   587   N NH2 . ARG A 1 85  ? -58.922  -27.577 82.795  1.00 67.64  ? 145 ARG A NH2 1 
ATOM   588   N N   . GLN A 1 86  ? -50.828  -22.827 83.528  1.00 75.49  ? 146 GLN A N   1 
ATOM   589   C CA  . GLN A 1 86  ? -49.528  -22.543 84.183  1.00 69.68  ? 146 GLN A CA  1 
ATOM   590   C C   . GLN A 1 86  ? -49.257  -21.038 84.129  1.00 61.68  ? 146 GLN A C   1 
ATOM   591   O O   . GLN A 1 86  ? -48.477  -20.588 84.957  1.00 57.27  ? 146 GLN A O   1 
ATOM   592   C CB  . GLN A 1 86  ? -48.424  -23.403 83.584  1.00 70.02  ? 146 GLN A CB  1 
ATOM   593   C CG  . GLN A 1 86  ? -48.514  -24.833 84.097  1.00 70.98  ? 146 GLN A CG  1 
ATOM   594   C CD  . GLN A 1 86  ? -47.446  -25.727 83.510  1.00 82.44  ? 146 GLN A CD  1 
ATOM   595   O OE1 . GLN A 1 86  ? -47.665  -26.492 82.564  1.00 84.10  ? 146 GLN A OE1 1 
ATOM   596   N NE2 . GLN A 1 86  ? -46.253  -25.638 84.076  1.00 95.58  ? 146 GLN A NE2 1 
ATOM   597   N N   . TYR A 1 87  ? -49.908  -20.267 83.253  1.00 57.29  ? 147 TYR A N   1 
ATOM   598   C CA  . TYR A 1 87  ? -49.836  -18.785 83.306  1.00 63.65  ? 147 TYR A CA  1 
ATOM   599   C C   . TYR A 1 87  ? -50.484  -18.322 84.607  1.00 64.46  ? 147 TYR A C   1 
ATOM   600   O O   . TYR A 1 87  ? -51.531  -18.904 85.011  1.00 66.89  ? 147 TYR A O   1 
ATOM   601   C CB  . TYR A 1 87  ? -50.444  -18.141 82.048  1.00 69.76  ? 147 TYR A CB  1 
ATOM   602   C CG  . TYR A 1 87  ? -49.567  -18.295 80.840  1.00 68.10  ? 147 TYR A CG  1 
ATOM   603   C CD1 . TYR A 1 87  ? -48.418  -17.533 80.722  1.00 71.04  ? 147 TYR A CD1 1 
ATOM   604   C CD2 . TYR A 1 87  ? -49.791  -19.280 79.893  1.00 68.94  ? 147 TYR A CD2 1 
ATOM   605   C CE1 . TYR A 1 87  ? -47.545  -17.700 79.662  1.00 68.18  ? 147 TYR A CE1 1 
ATOM   606   C CE2 . TYR A 1 87  ? -48.913  -19.474 78.830  1.00 67.72  ? 147 TYR A CE2 1 
ATOM   607   C CZ  . TYR A 1 87  ? -47.787  -18.675 78.717  1.00 62.82  ? 147 TYR A CZ  1 
ATOM   608   O OH  . TYR A 1 87  ? -46.882  -18.770 77.704  1.00 68.76  ? 147 TYR A OH  1 
ATOM   609   N N   . GLN A 1 88  ? -49.888  -17.306 85.232  1.00 58.94  ? 148 GLN A N   1 
ATOM   610   C CA  . GLN A 1 88  ? -50.338  -16.883 86.571  1.00 69.00  ? 148 GLN A CA  1 
ATOM   611   C C   . GLN A 1 88  ? -51.432  -15.839 86.439  1.00 62.05  ? 148 GLN A C   1 
ATOM   612   O O   . GLN A 1 88  ? -52.482  -16.086 87.009  1.00 74.16  ? 148 GLN A O   1 
ATOM   613   C CB  . GLN A 1 88  ? -49.167  -16.398 87.401  1.00 93.98  ? 148 GLN A CB  1 
ATOM   614   C CG  . GLN A 1 88  ? -48.166  -17.510 87.667  1.00 106.37 ? 148 GLN A CG  1 
ATOM   615   C CD  . GLN A 1 88  ? -48.537  -18.393 88.839  1.00 105.81 ? 148 GLN A CD  1 
ATOM   616   O OE1 . GLN A 1 88  ? -48.199  -19.574 88.882  1.00 104.69 ? 148 GLN A OE1 1 
ATOM   617   N NE2 . GLN A 1 88  ? -49.234  -17.829 89.811  1.00 97.77  ? 148 GLN A NE2 1 
ATOM   618   N N   . THR A 1 89  ? -51.235  -14.747 85.710  1.00 62.32  ? 149 THR A N   1 
ATOM   619   C CA  . THR A 1 89  ? -52.273  -13.676 85.653  1.00 67.13  ? 149 THR A CA  1 
ATOM   620   C C   . THR A 1 89  ? -53.328  -14.064 84.607  1.00 68.79  ? 149 THR A C   1 
ATOM   621   O O   . THR A 1 89  ? -53.098  -14.941 83.778  1.00 55.10  ? 149 THR A O   1 
ATOM   622   C CB  . THR A 1 89  ? -51.658  -12.269 85.593  1.00 60.91  ? 149 THR A CB  1 
ATOM   623   O OG1 . THR A 1 89  ? -52.520  -11.294 85.007  1.00 81.54  ? 149 THR A OG1 1 
ATOM   624   C CG2 . THR A 1 89  ? -50.388  -12.166 84.808  1.00 57.58  ? 149 THR A CG2 1 
ATOM   625   N N   . PRO A 1 90  ? -54.585  -13.565 84.737  1.00 65.05  ? 150 PRO A N   1 
ATOM   626   C CA  . PRO A 1 90  ? -55.598  -13.781 83.709  1.00 61.34  ? 150 PRO A CA  1 
ATOM   627   C C   . PRO A 1 90  ? -55.196  -13.174 82.359  1.00 63.09  ? 150 PRO A C   1 
ATOM   628   O O   . PRO A 1 90  ? -55.299  -13.893 81.384  1.00 64.17  ? 150 PRO A O   1 
ATOM   629   C CB  . PRO A 1 90  ? -56.842  -13.094 84.286  1.00 62.48  ? 150 PRO A CB  1 
ATOM   630   C CG  . PRO A 1 90  ? -56.603  -13.148 85.778  1.00 54.51  ? 150 PRO A CG  1 
ATOM   631   C CD  . PRO A 1 90  ? -55.140  -12.850 85.902  1.00 52.33  ? 150 PRO A CD  1 
ATOM   632   N N   . LEU A 1 91  ? -54.726  -11.913 82.343  1.00 60.68  ? 151 LEU A N   1 
ATOM   633   C CA  . LEU A 1 91  ? -54.204  -11.217 81.129  1.00 50.83  ? 151 LEU A CA  1 
ATOM   634   C C   . LEU A 1 91  ? -53.210  -12.117 80.366  1.00 50.02  ? 151 LEU A C   1 
ATOM   635   O O   . LEU A 1 91  ? -53.302  -12.193 79.167  1.00 48.27  ? 151 LEU A O   1 
ATOM   636   C CB  . LEU A 1 91  ? -53.548  -9.888  81.498  1.00 47.01  ? 151 LEU A CB  1 
ATOM   637   C CG  . LEU A 1 91  ? -53.132  -9.031  80.304  1.00 43.40  ? 151 LEU A CG  1 
ATOM   638   C CD1 . LEU A 1 91  ? -54.281  -8.879  79.327  1.00 46.68  ? 151 LEU A CD1 1 
ATOM   639   C CD2 . LEU A 1 91  ? -52.665  -7.652  80.734  1.00 45.66  ? 151 LEU A CD2 1 
ATOM   640   N N   . GLN A 1 92  ? -52.311  -12.825 81.029  1.00 55.51  ? 152 GLN A N   1 
ATOM   641   C CA  . GLN A 1 92  ? -51.390  -13.799 80.358  1.00 59.09  ? 152 GLN A CA  1 
ATOM   642   C C   . GLN A 1 92  ? -52.169  -14.926 79.672  1.00 50.95  ? 152 GLN A C   1 
ATOM   643   O O   . GLN A 1 92  ? -51.736  -15.343 78.604  1.00 60.17  ? 152 GLN A O   1 
ATOM   644   C CB  . GLN A 1 92  ? -50.356  -14.363 81.334  1.00 66.57  ? 152 GLN A CB  1 
ATOM   645   C CG  . GLN A 1 92  ? -49.281  -13.327 81.641  1.00 82.11  ? 152 GLN A CG  1 
ATOM   646   C CD  . GLN A 1 92  ? -48.269  -13.796 82.648  1.00 88.23  ? 152 GLN A CD  1 
ATOM   647   O OE1 . GLN A 1 92  ? -48.479  -14.806 83.335  1.00 80.30  ? 152 GLN A OE1 1 
ATOM   648   N NE2 . GLN A 1 92  ? -47.154  -13.069 82.699  1.00 102.69 ? 152 GLN A NE2 1 
ATOM   649   N N   . ARG A 1 93  ? -53.263  -15.413 80.242  1.00 45.20  ? 153 ARG A N   1 
ATOM   650   C CA  . ARG A 1 93  ? -54.097  -16.442 79.563  1.00 48.39  ? 153 ARG A CA  1 
ATOM   651   C C   . ARG A 1 93  ? -54.888  -15.816 78.401  1.00 47.54  ? 153 ARG A C   1 
ATOM   652   O O   . ARG A 1 93  ? -55.168  -16.545 77.425  1.00 45.23  ? 153 ARG A O   1 
ATOM   653   C CB  . ARG A 1 93  ? -55.052  -17.115 80.544  1.00 51.30  ? 153 ARG A CB  1 
ATOM   654   C CG  . ARG A 1 93  ? -54.359  -17.941 81.610  1.00 54.86  ? 153 ARG A CG  1 
ATOM   655   C CD  . ARG A 1 93  ? -55.152  -17.958 82.894  1.00 62.98  ? 153 ARG A CD  1 
ATOM   656   N NE  . ARG A 1 93  ? -55.054  -19.202 83.630  1.00 73.21  ? 153 ARG A NE  1 
ATOM   657   C CZ  . ARG A 1 93  ? -54.675  -19.300 84.894  1.00 88.30  ? 153 ARG A CZ  1 
ATOM   658   N NH1 . ARG A 1 93  ? -54.336  -18.222 85.586  1.00 96.54  ? 153 ARG A NH1 1 
ATOM   659   N NH2 . ARG A 1 93  ? -54.629  -20.488 85.472  1.00 85.11  ? 153 ARG A NH2 1 
ATOM   660   N N   . TYR A 1 94  ? -55.244  -14.528 78.485  1.00 43.89  ? 154 TYR A N   1 
ATOM   661   C CA  . TYR A 1 94  ? -55.891  -13.766 77.376  1.00 43.36  ? 154 TYR A CA  1 
ATOM   662   C C   . TYR A 1 94  ? -54.934  -13.668 76.199  1.00 39.79  ? 154 TYR A C   1 
ATOM   663   O O   . TYR A 1 94  ? -55.388  -13.843 75.060  1.00 40.91  ? 154 TYR A O   1 
ATOM   664   C CB  . TYR A 1 94  ? -56.330  -12.350 77.787  1.00 49.05  ? 154 TYR A CB  1 
ATOM   665   C CG  . TYR A 1 94  ? -56.780  -11.454 76.662  1.00 43.99  ? 154 TYR A CG  1 
ATOM   666   C CD1 . TYR A 1 94  ? -58.064  -11.532 76.153  1.00 44.53  ? 154 TYR A CD1 1 
ATOM   667   C CD2 . TYR A 1 94  ? -55.918  -10.560 76.087  1.00 43.64  ? 154 TYR A CD2 1 
ATOM   668   C CE1 . TYR A 1 94  ? -58.476  -10.744 75.101  1.00 48.11  ? 154 TYR A CE1 1 
ATOM   669   C CE2 . TYR A 1 94  ? -56.325  -9.740  75.049  1.00 52.36  ? 154 TYR A CE2 1 
ATOM   670   C CZ  . TYR A 1 94  ? -57.606  -9.842  74.536  1.00 52.90  ? 154 TYR A CZ  1 
ATOM   671   O OH  . TYR A 1 94  ? -58.028  -9.078  73.476  1.00 64.55  ? 154 TYR A OH  1 
ATOM   672   N N   . ILE A 1 95  ? -53.665  -13.378 76.477  1.00 41.80  ? 155 ILE A N   1 
ATOM   673   C CA  . ILE A 1 95  ? -52.610  -13.229 75.434  1.00 42.84  ? 155 ILE A CA  1 
ATOM   674   C C   . ILE A 1 95  ? -52.462  -14.584 74.738  1.00 41.28  ? 155 ILE A C   1 
ATOM   675   O O   . ILE A 1 95  ? -52.406  -14.604 73.485  1.00 41.39  ? 155 ILE A O   1 
ATOM   676   C CB  . ILE A 1 95  ? -51.236  -12.789 75.985  1.00 44.24  ? 155 ILE A CB  1 
ATOM   677   C CG1 . ILE A 1 95  ? -51.236  -11.624 76.975  1.00 48.74  ? 155 ILE A CG1 1 
ATOM   678   C CG2 . ILE A 1 95  ? -50.281  -12.556 74.831  1.00 44.71  ? 155 ILE A CG2 1 
ATOM   679   C CD1 . ILE A 1 95  ? -51.416  -10.287 76.375  1.00 48.23  ? 155 ILE A CD1 1 
ATOM   680   N N   . ALA A 1 96  ? -52.401  -15.676 75.511  1.00 44.65  ? 156 ALA A N   1 
ATOM   681   C CA  . ALA A 1 96  ? -52.195  -17.044 74.968  1.00 46.44  ? 156 ALA A CA  1 
ATOM   682   C C   . ALA A 1 96  ? -53.414  -17.451 74.131  1.00 44.27  ? 156 ALA A C   1 
ATOM   683   O O   . ALA A 1 96  ? -53.232  -18.185 73.171  1.00 43.74  ? 156 ALA A O   1 
ATOM   684   C CB  . ALA A 1 96  ? -51.911  -18.034 76.069  1.00 46.74  ? 156 ALA A CB  1 
ATOM   685   N N   . MET A 1 97  ? -54.606  -16.976 74.498  1.00 50.07  ? 157 MET A N   1 
ATOM   686   C CA  . MET A 1 97  ? -55.877  -17.314 73.812  1.00 46.78  ? 157 MET A CA  1 
ATOM   687   C C   . MET A 1 97  ? -55.917  -16.575 72.471  1.00 46.31  ? 157 MET A C   1 
ATOM   688   O O   . MET A 1 97  ? -56.174  -17.248 71.467  1.00 48.73  ? 157 MET A O   1 
ATOM   689   C CB  . MET A 1 97  ? -57.097  -16.949 74.673  1.00 49.50  ? 157 MET A CB  1 
ATOM   690   C CG  . MET A 1 97  ? -57.407  -17.931 75.801  1.00 47.56  ? 157 MET A CG  1 
ATOM   691   S SD  . MET A 1 97  ? -57.741  -19.660 75.316  1.00 48.73  ? 157 MET A SD  1 
ATOM   692   C CE  . MET A 1 97  ? -59.211  -19.518 74.292  1.00 48.15  ? 157 MET A CE  1 
ATOM   693   N N   . MET A 1 98  ? -55.581  -15.276 72.446  1.00 53.89  ? 158 MET A N   1 
ATOM   694   C CA  . MET A 1 98  ? -55.621  -14.414 71.220  1.00 58.71  ? 158 MET A CA  1 
ATOM   695   C C   . MET A 1 98  ? -54.561  -14.894 70.219  1.00 52.21  ? 158 MET A C   1 
ATOM   696   O O   . MET A 1 98  ? -54.887  -15.023 69.028  1.00 56.17  ? 158 MET A O   1 
ATOM   697   C CB  . MET A 1 98  ? -55.428  -12.921 71.525  1.00 56.00  ? 158 MET A CB  1 
ATOM   698   C CG  . MET A 1 98  ? -56.607  -12.318 72.309  1.00 63.20  ? 158 MET A CG  1 
ATOM   699   S SD  . MET A 1 98  ? -58.265  -12.698 71.609  1.00 73.15  ? 158 MET A SD  1 
ATOM   700   C CE  . MET A 1 98  ? -59.107  -13.481 72.973  1.00 74.67  ? 158 MET A CE  1 
ATOM   701   N N   . ASN A 1 99  ? -53.369  -15.231 70.706  1.00 54.67  ? 159 ASN A N   1 
ATOM   702   C CA  . ASN A 1 99  ? -52.296  -15.893 69.921  1.00 55.38  ? 159 ASN A CA  1 
ATOM   703   C C   . ASN A 1 99  ? -52.830  -17.157 69.219  1.00 49.71  ? 159 ASN A C   1 
ATOM   704   O O   . ASN A 1 99  ? -52.594  -17.270 68.012  1.00 56.78  ? 159 ASN A O   1 
ATOM   705   C CB  . ASN A 1 99  ? -51.080  -16.187 70.804  1.00 63.31  ? 159 ASN A CB  1 
ATOM   706   C CG  . ASN A 1 99  ? -49.796  -16.365 70.024  1.00 71.98  ? 159 ASN A CG  1 
ATOM   707   O OD1 . ASN A 1 99  ? -49.461  -15.562 69.140  1.00 84.07  ? 159 ASN A OD1 1 
ATOM   708   N ND2 . ASN A 1 99  ? -49.143  -17.489 70.282  1.00 75.58  ? 159 ASN A ND2 1 
ATOM   709   N N   . LEU A 1 100 ? -53.522  -18.074 69.921  1.00 46.06  ? 160 LEU A N   1 
ATOM   710   C CA  . LEU A 1 100 ? -54.043  -19.344 69.346  1.00 39.91  ? 160 LEU A CA  1 
ATOM   711   C C   . LEU A 1 100 ? -55.121  -19.034 68.302  1.00 47.90  ? 160 LEU A C   1 
ATOM   712   O O   . LEU A 1 100 ? -55.102  -19.644 67.203  1.00 47.22  ? 160 LEU A O   1 
ATOM   713   C CB  . LEU A 1 100 ? -54.616  -20.209 70.465  1.00 40.42  ? 160 LEU A CB  1 
ATOM   714   C CG  . LEU A 1 100 ? -55.289  -21.518 70.022  1.00 41.49  ? 160 LEU A CG  1 
ATOM   715   C CD1 . LEU A 1 100 ? -54.324  -22.483 69.341  1.00 35.45  ? 160 LEU A CD1 1 
ATOM   716   C CD2 . LEU A 1 100 ? -55.915  -22.197 71.215  1.00 48.28  ? 160 LEU A CD2 1 
ATOM   717   N N   . GLN A 1 101 ? -56.038  -18.113 68.610  1.00 60.75  ? 161 GLN A N   1 
ATOM   718   C CA  . GLN A 1 101 ? -57.091  -17.675 67.650  1.00 58.84  ? 161 GLN A CA  1 
ATOM   719   C C   . GLN A 1 101 ? -56.443  -17.356 66.309  1.00 58.06  ? 161 GLN A C   1 
ATOM   720   O O   . GLN A 1 101 ? -57.043  -17.767 65.264  1.00 60.42  ? 161 GLN A O   1 
ATOM   721   C CB  . GLN A 1 101 ? -57.850  -16.450 68.150  1.00 56.28  ? 161 GLN A CB  1 
ATOM   722   C CG  . GLN A 1 101 ? -59.070  -16.166 67.301  1.00 55.00  ? 161 GLN A CG  1 
ATOM   723   C CD  . GLN A 1 101 ? -59.744  -14.888 67.690  1.00 52.98  ? 161 GLN A CD  1 
ATOM   724   O OE1 . GLN A 1 101 ? -59.083  -13.865 67.821  1.00 54.60  ? 161 GLN A OE1 1 
ATOM   725   N NE2 . GLN A 1 101 ? -61.064  -14.915 67.697  1.00 54.79  ? 161 GLN A NE2 1 
ATOM   726   N N   . GLU A 1 102 ? -55.262  -16.714 66.355  1.00 54.81  ? 162 GLU A N   1 
ATOM   727   C CA  . GLU A 1 102 ? -54.539  -16.171 65.174  1.00 54.49  ? 162 GLU A CA  1 
ATOM   728   C C   . GLU A 1 102 ? -53.429  -17.120 64.713  1.00 48.19  ? 162 GLU A C   1 
ATOM   729   O O   . GLU A 1 102 ? -52.519  -16.607 64.070  1.00 61.80  ? 162 GLU A O   1 
ATOM   730   C CB  . GLU A 1 102 ? -53.981  -14.773 65.479  1.00 57.97  ? 162 GLU A CB  1 
ATOM   731   C CG  . GLU A 1 102 ? -55.055  -13.761 65.843  1.00 71.46  ? 162 GLU A CG  1 
ATOM   732   C CD  . GLU A 1 102 ? -56.149  -13.517 64.790  1.00 96.70  ? 162 GLU A CD  1 
ATOM   733   O OE1 . GLU A 1 102 ? -57.365  -13.767 65.088  1.00 99.43  ? 162 GLU A OE1 1 
ATOM   734   O OE2 . GLU A 1 102 ? -55.809  -13.059 63.674  1.00 102.07 ? 162 GLU A OE2 1 
ATOM   735   N N   . THR A 1 103 ? -53.488  -18.422 65.003  1.00 44.92  ? 163 THR A N   1 
ATOM   736   C CA  . THR A 1 103 ? -52.507  -19.424 64.482  1.00 51.43  ? 163 THR A CA  1 
ATOM   737   C C   . THR A 1 103 ? -53.220  -20.714 64.066  1.00 52.50  ? 163 THR A C   1 
ATOM   738   O O   . THR A 1 103 ? -52.775  -21.321 63.067  1.00 59.92  ? 163 THR A O   1 
ATOM   739   C CB  . THR A 1 103 ? -51.349  -19.744 65.450  1.00 51.74  ? 163 THR A CB  1 
ATOM   740   O OG1 . THR A 1 103 ? -51.749  -20.629 66.498  1.00 58.57  ? 163 THR A OG1 1 
ATOM   741   C CG2 . THR A 1 103 ? -50.739  -18.507 66.072  1.00 54.32  ? 163 THR A CG2 1 
ATOM   742   N N   . ASP A 1 104 ? -54.220  -21.134 64.844  1.00 48.55  ? 164 ASP A N   1 
ATOM   743   C CA  . ASP A 1 104 ? -55.102  -22.289 64.556  1.00 48.10  ? 164 ASP A CA  1 
ATOM   744   C C   . ASP A 1 104 ? -56.518  -21.941 65.042  1.00 54.25  ? 164 ASP A C   1 
ATOM   745   O O   . ASP A 1 104 ? -56.808  -22.115 66.244  1.00 47.24  ? 164 ASP A O   1 
ATOM   746   C CB  . ASP A 1 104 ? -54.518  -23.566 65.160  1.00 47.27  ? 164 ASP A CB  1 
ATOM   747   C CG  . ASP A 1 104 ? -55.286  -24.835 64.823  1.00 45.56  ? 164 ASP A CG  1 
ATOM   748   O OD1 . ASP A 1 104 ? -56.444  -24.747 64.277  1.00 45.58  ? 164 ASP A OD1 1 
ATOM   749   O OD2 . ASP A 1 104 ? -54.743  -25.904 65.133  1.00 40.95  ? 164 ASP A OD2 1 
ATOM   750   N N   . GLU A 1 105 ? -57.364  -21.484 64.113  1.00 57.29  ? 165 GLU A N   1 
ATOM   751   C CA  . GLU A 1 105 ? -58.718  -20.930 64.367  1.00 58.30  ? 165 GLU A CA  1 
ATOM   752   C C   . GLU A 1 105 ? -59.634  -22.079 64.785  1.00 56.22  ? 165 GLU A C   1 
ATOM   753   O O   . GLU A 1 105 ? -60.420  -21.921 65.744  1.00 54.13  ? 165 GLU A O   1 
ATOM   754   C CB  . GLU A 1 105 ? -59.153  -20.224 63.084  1.00 56.36  ? 165 GLU A CB  1 
ATOM   755   C CG  . GLU A 1 105 ? -60.518  -19.616 63.072  1.00 53.69  ? 165 GLU A CG  1 
ATOM   756   C CD  . GLU A 1 105 ? -61.011  -19.508 61.636  1.00 57.71  ? 165 GLU A CD  1 
ATOM   757   O OE1 . GLU A 1 105 ? -61.540  -20.582 61.060  1.00 45.65  ? 165 GLU A OE1 1 
ATOM   758   O OE2 . GLU A 1 105 ? -60.828  -18.362 61.088  1.00 52.79  ? 165 GLU A OE2 1 
ATOM   759   N N   . ARG A 1 106 ? -59.501  -23.221 64.121  1.00 53.48  ? 166 ARG A N   1 
ATOM   760   C CA  . ARG A 1 106 ? -60.341  -24.401 64.438  1.00 60.44  ? 166 ARG A CA  1 
ATOM   761   C C   . ARG A 1 106 ? -60.012  -24.949 65.844  1.00 62.98  ? 166 ARG A C   1 
ATOM   762   O O   . ARG A 1 106 ? -60.948  -25.323 66.574  1.00 54.08  ? 166 ARG A O   1 
ATOM   763   C CB  . ARG A 1 106 ? -60.139  -25.465 63.357  1.00 77.19  ? 166 ARG A CB  1 
ATOM   764   C CG  . ARG A 1 106 ? -61.205  -25.514 62.256  1.00 80.24  ? 166 ARG A CG  1 
ATOM   765   C CD  . ARG A 1 106 ? -61.498  -24.278 61.396  1.00 82.99  ? 166 ARG A CD  1 
ATOM   766   N NE  . ARG A 1 106 ? -62.250  -24.763 60.247  1.00 75.90  ? 166 ARG A NE  1 
ATOM   767   C CZ  . ARG A 1 106 ? -61.840  -24.700 58.989  1.00 87.56  ? 166 ARG A CZ  1 
ATOM   768   N NH1 . ARG A 1 106 ? -60.706  -24.103 58.668  1.00 100.96 ? 166 ARG A NH1 1 
ATOM   769   N NH2 . ARG A 1 106 ? -62.578  -25.220 58.026  1.00 98.30  ? 166 ARG A NH2 1 
ATOM   770   N N   . LEU A 1 107 ? -58.733  -25.033 66.226  1.00 58.94  ? 167 LEU A N   1 
ATOM   771   C CA  . LEU A 1 107 ? -58.343  -25.505 67.588  1.00 50.42  ? 167 LEU A CA  1 
ATOM   772   C C   . LEU A 1 107 ? -58.823  -24.490 68.639  1.00 43.28  ? 167 LEU A C   1 
ATOM   773   O O   . LEU A 1 107 ? -59.343  -24.904 69.667  1.00 42.55  ? 167 LEU A O   1 
ATOM   774   C CB  . LEU A 1 107 ? -56.825  -25.686 67.656  1.00 52.73  ? 167 LEU A CB  1 
ATOM   775   C CG  . LEU A 1 107 ? -56.282  -26.089 69.032  1.00 51.02  ? 167 LEU A CG  1 
ATOM   776   C CD1 . LEU A 1 107 ? -56.906  -27.386 69.480  1.00 48.23  ? 167 LEU A CD1 1 
ATOM   777   C CD2 . LEU A 1 107 ? -54.762  -26.172 69.045  1.00 42.95  ? 167 LEU A CD2 1 
ATOM   778   N N   . PHE A 1 108 ? -58.681  -23.201 68.356  1.00 39.32  ? 168 PHE A N   1 
ATOM   779   C CA  . PHE A 1 108 ? -59.126  -22.089 69.223  1.00 36.86  ? 168 PHE A CA  1 
ATOM   780   C C   . PHE A 1 108 ? -60.601  -22.214 69.527  1.00 31.23  ? 168 PHE A C   1 
ATOM   781   O O   . PHE A 1 108 ? -60.958  -22.087 70.683  1.00 38.75  ? 168 PHE A O   1 
ATOM   782   C CB  . PHE A 1 108 ? -58.867  -20.734 68.567  1.00 41.31  ? 168 PHE A CB  1 
ATOM   783   C CG  . PHE A 1 108 ? -59.523  -19.595 69.284  1.00 40.40  ? 168 PHE A CG  1 
ATOM   784   C CD1 . PHE A 1 108 ? -58.912  -18.998 70.364  1.00 45.16  ? 168 PHE A CD1 1 
ATOM   785   C CD2 . PHE A 1 108 ? -60.744  -19.126 68.873  1.00 39.18  ? 168 PHE A CD2 1 
ATOM   786   C CE1 . PHE A 1 108 ? -59.512  -17.923 71.002  1.00 57.09  ? 168 PHE A CE1 1 
ATOM   787   C CE2 . PHE A 1 108 ? -61.345  -18.071 69.527  1.00 50.51  ? 168 PHE A CE2 1 
ATOM   788   C CZ  . PHE A 1 108 ? -60.723  -17.452 70.582  1.00 54.06  ? 168 PHE A CZ  1 
ATOM   789   N N   . TYR A 1 109 ? -61.435  -22.414 68.519  1.00 33.86  ? 169 TYR A N   1 
ATOM   790   C CA  . TYR A 1 109 ? -62.908  -22.470 68.723  1.00 40.59  ? 169 TYR A CA  1 
ATOM   791   C C   . TYR A 1 109 ? -63.246  -23.808 69.387  1.00 51.43  ? 169 TYR A C   1 
ATOM   792   O O   . TYR A 1 109 ? -63.941  -23.744 70.433  1.00 61.73  ? 169 TYR A O   1 
ATOM   793   C CB  . TYR A 1 109 ? -63.712  -22.100 67.467  1.00 37.03  ? 169 TYR A CB  1 
ATOM   794   C CG  . TYR A 1 109 ? -63.639  -20.623 67.149  1.00 37.09  ? 169 TYR A CG  1 
ATOM   795   C CD1 . TYR A 1 109 ? -64.162  -19.674 68.009  1.00 36.58  ? 169 TYR A CD1 1 
ATOM   796   C CD2 . TYR A 1 109 ? -62.968  -20.153 66.037  1.00 36.78  ? 169 TYR A CD2 1 
ATOM   797   C CE1 . TYR A 1 109 ? -64.083  -18.311 67.750  1.00 38.38  ? 169 TYR A CE1 1 
ATOM   798   C CE2 . TYR A 1 109 ? -62.873  -18.797 65.758  1.00 42.41  ? 169 TYR A CE2 1 
ATOM   799   C CZ  . TYR A 1 109 ? -63.439  -17.867 66.613  1.00 43.04  ? 169 TYR A CZ  1 
ATOM   800   O OH  . TYR A 1 109 ? -63.327  -16.533 66.337  1.00 48.00  ? 169 TYR A OH  1 
ATOM   801   N N   . LYS A 1 110 ? -62.721  -24.948 68.908  1.00 52.73  ? 170 LYS A N   1 
ATOM   802   C CA  . LYS A 1 110 ? -63.063  -26.282 69.489  1.00 54.94  ? 170 LYS A CA  1 
ATOM   803   C C   . LYS A 1 110 ? -62.670  -26.318 70.978  1.00 54.73  ? 170 LYS A C   1 
ATOM   804   O O   . LYS A 1 110 ? -63.430  -26.869 71.800  1.00 52.30  ? 170 LYS A O   1 
ATOM   805   C CB  . LYS A 1 110 ? -62.399  -27.393 68.674  1.00 62.93  ? 170 LYS A CB  1 
ATOM   806   C CG  . LYS A 1 110 ? -63.227  -28.654 68.513  1.00 70.52  ? 170 LYS A CG  1 
ATOM   807   C CD  . LYS A 1 110 ? -63.094  -29.619 69.636  1.00 76.64  ? 170 LYS A CD  1 
ATOM   808   C CE  . LYS A 1 110 ? -64.078  -30.739 69.437  1.00 86.42  ? 170 LYS A CE  1 
ATOM   809   N NZ  . LYS A 1 110 ? -63.945  -31.714 70.533  1.00 96.64  ? 170 LYS A NZ  1 
ATOM   810   N N   . LEU A 1 111 ? -61.554  -25.683 71.329  1.00 52.11  ? 171 LEU A N   1 
ATOM   811   C CA  . LEU A 1 111 ? -61.087  -25.578 72.731  1.00 53.97  ? 171 LEU A CA  1 
ATOM   812   C C   . LEU A 1 111 ? -62.073  -24.700 73.514  1.00 52.87  ? 171 LEU A C   1 
ATOM   813   O O   . LEU A 1 111 ? -62.617  -25.203 74.498  1.00 62.14  ? 171 LEU A O   1 
ATOM   814   C CB  . LEU A 1 111 ? -59.669  -24.993 72.727  1.00 58.77  ? 171 LEU A CB  1 
ATOM   815   C CG  . LEU A 1 111 ? -59.067  -24.605 74.078  1.00 56.23  ? 171 LEU A CG  1 
ATOM   816   C CD1 . LEU A 1 111 ? -57.786  -25.389 74.287  1.00 61.34  ? 171 LEU A CD1 1 
ATOM   817   C CD2 . LEU A 1 111 ? -58.846  -23.090 74.173  1.00 49.65  ? 171 LEU A CD2 1 
ATOM   818   N N   . LEU A 1 112 ? -62.303  -23.456 73.072  1.00 43.25  ? 172 LEU A N   1 
ATOM   819   C CA  . LEU A 1 112 ? -63.163  -22.471 73.766  1.00 39.25  ? 172 LEU A CA  1 
ATOM   820   C C   . LEU A 1 112 ? -64.538  -23.088 74.035  1.00 42.84  ? 172 LEU A C   1 
ATOM   821   O O   . LEU A 1 112 ? -65.001  -22.967 75.158  1.00 45.95  ? 172 LEU A O   1 
ATOM   822   C CB  . LEU A 1 112 ? -63.291  -21.204 72.921  1.00 43.01  ? 172 LEU A CB  1 
ATOM   823   C CG  . LEU A 1 112 ? -64.168  -20.107 73.520  1.00 41.67  ? 172 LEU A CG  1 
ATOM   824   C CD1 . LEU A 1 112 ? -63.679  -19.667 74.879  1.00 41.22  ? 172 LEU A CD1 1 
ATOM   825   C CD2 . LEU A 1 112 ? -64.245  -18.920 72.591  1.00 49.32  ? 172 LEU A CD2 1 
ATOM   826   N N   . ILE A 1 113 ? -65.181  -23.741 73.066  1.00 46.85  ? 173 ILE A N   1 
ATOM   827   C CA  . ILE A 1 113 ? -66.516  -24.398 73.276  1.00 49.08  ? 173 ILE A CA  1 
ATOM   828   C C   . ILE A 1 113 ? -66.395  -25.471 74.368  1.00 45.77  ? 173 ILE A C   1 
ATOM   829   O O   . ILE A 1 113 ? -67.095  -25.331 75.379  1.00 47.53  ? 173 ILE A O   1 
ATOM   830   C CB  . ILE A 1 113 ? -67.079  -24.946 71.945  1.00 55.46  ? 173 ILE A CB  1 
ATOM   831   C CG1 . ILE A 1 113 ? -67.382  -23.778 70.993  1.00 52.37  ? 173 ILE A CG1 1 
ATOM   832   C CG2 . ILE A 1 113 ? -68.295  -25.846 72.146  1.00 55.17  ? 173 ILE A CG2 1 
ATOM   833   C CD1 . ILE A 1 113 ? -67.489  -24.165 69.534  1.00 48.18  ? 173 ILE A CD1 1 
ATOM   834   N N   . ASP A 1 114 ? -65.507  -26.455 74.207  1.00 47.57  ? 174 ASP A N   1 
ATOM   835   C CA  . ASP A 1 114 ? -65.406  -27.626 75.124  1.00 52.31  ? 174 ASP A CA  1 
ATOM   836   C C   . ASP A 1 114 ? -65.028  -27.182 76.541  1.00 53.32  ? 174 ASP A C   1 
ATOM   837   O O   . ASP A 1 114 ? -65.147  -28.019 77.440  1.00 53.62  ? 174 ASP A O   1 
ATOM   838   C CB  . ASP A 1 114 ? -64.392  -28.661 74.630  1.00 57.31  ? 174 ASP A CB  1 
ATOM   839   C CG  . ASP A 1 114 ? -64.765  -29.278 73.297  1.00 61.95  ? 174 ASP A CG  1 
ATOM   840   O OD1 . ASP A 1 114 ? -65.838  -28.936 72.789  1.00 68.72  ? 174 ASP A OD1 1 
ATOM   841   O OD2 . ASP A 1 114 ? -63.973  -30.079 72.776  1.00 63.01  ? 174 ASP A OD2 1 
ATOM   842   N N   . ASN A 1 115 ? -64.556  -25.942 76.729  1.00 51.24  ? 175 ASN A N   1 
ATOM   843   C CA  . ASN A 1 115 ? -64.011  -25.426 78.019  1.00 55.72  ? 175 ASN A CA  1 
ATOM   844   C C   . ASN A 1 115 ? -64.593  -24.038 78.284  1.00 52.81  ? 175 ASN A C   1 
ATOM   845   O O   . ASN A 1 115 ? -63.906  -23.204 78.886  1.00 61.32  ? 175 ASN A O   1 
ATOM   846   C CB  . ASN A 1 115 ? -62.475  -25.424 78.022  1.00 54.10  ? 175 ASN A CB  1 
ATOM   847   C CG  . ASN A 1 115 ? -61.893  -26.831 77.923  1.00 59.57  ? 175 ASN A CG  1 
ATOM   848   O OD1 . ASN A 1 115 ? -61.803  -27.562 78.902  1.00 52.29  ? 175 ASN A OD1 1 
ATOM   849   N ND2 . ASN A 1 115 ? -61.509  -27.243 76.728  1.00 65.57  ? 175 ASN A ND2 1 
ATOM   850   N N   . VAL A 1 116 ? -65.846  -23.815 77.888  1.00 54.12  ? 176 VAL A N   1 
ATOM   851   C CA  . VAL A 1 116 ? -66.449  -22.452 77.768  1.00 50.99  ? 176 VAL A CA  1 
ATOM   852   C C   . VAL A 1 116 ? -66.559  -21.785 79.139  1.00 54.49  ? 176 VAL A C   1 
ATOM   853   O O   . VAL A 1 116 ? -66.378  -20.547 79.205  1.00 58.31  ? 176 VAL A O   1 
ATOM   854   C CB  . VAL A 1 116 ? -67.808  -22.483 77.051  1.00 44.96  ? 176 VAL A CB  1 
ATOM   855   C CG1 . VAL A 1 116 ? -68.771  -23.497 77.659  1.00 43.55  ? 176 VAL A CG1 1 
ATOM   856   C CG2 . VAL A 1 116 ? -68.425  -21.091 77.005  1.00 48.64  ? 176 VAL A CG2 1 
ATOM   857   N N   . VAL A 1 117 ? -66.873  -22.556 80.182  1.00 55.78  ? 177 VAL A N   1 
ATOM   858   C CA  . VAL A 1 117 ? -67.140  -22.017 81.547  1.00 54.14  ? 177 VAL A CA  1 
ATOM   859   C C   . VAL A 1 117 ? -65.814  -21.546 82.146  1.00 58.43  ? 177 VAL A C   1 
ATOM   860   O O   . VAL A 1 117 ? -65.832  -20.457 82.802  1.00 52.11  ? 177 VAL A O   1 
ATOM   861   C CB  . VAL A 1 117 ? -67.846  -23.062 82.427  1.00 45.11  ? 177 VAL A CB  1 
ATOM   862   C CG1 . VAL A 1 117 ? -67.862  -22.650 83.886  1.00 46.03  ? 177 VAL A CG1 1 
ATOM   863   C CG2 . VAL A 1 117 ? -69.253  -23.329 81.916  1.00 41.75  ? 177 VAL A CG2 1 
ATOM   864   N N   . GLU A 1 118 ? -64.739  -22.330 81.925  1.00 58.00  ? 178 GLU A N   1 
ATOM   865   C CA  . GLU A 1 118 ? -63.380  -22.097 82.488  1.00 60.60  ? 178 GLU A CA  1 
ATOM   866   C C   . GLU A 1 118 ? -62.718  -20.904 81.795  1.00 60.47  ? 178 GLU A C   1 
ATOM   867   O O   . GLU A 1 118 ? -62.037  -20.137 82.499  1.00 69.38  ? 178 GLU A O   1 
ATOM   868   C CB  . GLU A 1 118 ? -62.497  -23.345 82.356  1.00 61.16  ? 178 GLU A CB  1 
ATOM   869   C CG  . GLU A 1 118 ? -61.093  -23.155 82.908  1.00 64.72  ? 178 GLU A CG  1 
ATOM   870   C CD  . GLU A 1 118 ? -60.315  -24.417 83.222  1.00 67.96  ? 178 GLU A CD  1 
ATOM   871   O OE1 . GLU A 1 118 ? -60.889  -25.538 83.013  1.00 60.32  ? 178 GLU A OE1 1 
ATOM   872   O OE2 . GLU A 1 118 ? -59.119  -24.266 83.661  1.00 59.79  ? 178 GLU A OE2 1 
ATOM   873   N N   . LEU A 1 119 ? -62.938  -20.746 80.485  1.00 60.72  ? 179 LEU A N   1 
ATOM   874   C CA  . LEU A 1 119 ? -62.133  -19.872 79.590  1.00 62.83  ? 179 LEU A CA  1 
ATOM   875   C C   . LEU A 1 119 ? -62.858  -18.548 79.355  1.00 57.62  ? 179 LEU A C   1 
ATOM   876   O O   . LEU A 1 119 ? -62.204  -17.592 78.964  1.00 63.95  ? 179 LEU A O   1 
ATOM   877   C CB  . LEU A 1 119 ? -61.868  -20.591 78.255  1.00 64.18  ? 179 LEU A CB  1 
ATOM   878   C CG  . LEU A 1 119 ? -60.913  -21.799 78.306  1.00 63.86  ? 179 LEU A CG  1 
ATOM   879   C CD1 . LEU A 1 119 ? -60.513  -22.268 76.922  1.00 65.33  ? 179 LEU A CD1 1 
ATOM   880   C CD2 . LEU A 1 119 ? -59.662  -21.536 79.120  1.00 60.43  ? 179 LEU A CD2 1 
ATOM   881   N N   . LEU A 1 120 ? -64.165  -18.499 79.547  1.00 53.23  ? 180 LEU A N   1 
ATOM   882   C CA  . LEU A 1 120 ? -64.981  -17.327 79.139  1.00 58.30  ? 180 LEU A CA  1 
ATOM   883   C C   . LEU A 1 120 ? -64.549  -16.070 79.892  1.00 51.23  ? 180 LEU A C   1 
ATOM   884   O O   . LEU A 1 120 ? -64.565  -14.964 79.339  1.00 37.95  ? 180 LEU A O   1 
ATOM   885   C CB  . LEU A 1 120 ? -66.458  -17.653 79.379  1.00 68.75  ? 180 LEU A CB  1 
ATOM   886   C CG  . LEU A 1 120 ? -67.457  -16.682 78.762  1.00 71.42  ? 180 LEU A CG  1 
ATOM   887   C CD1 . LEU A 1 120 ? -67.159  -16.452 77.292  1.00 72.74  ? 180 LEU A CD1 1 
ATOM   888   C CD2 . LEU A 1 120 ? -68.867  -17.206 78.955  1.00 70.29  ? 180 LEU A CD2 1 
ATOM   889   N N   . PRO A 1 121 ? -64.170  -16.177 81.185  1.00 54.72  ? 181 PRO A N   1 
ATOM   890   C CA  . PRO A 1 121 ? -63.756  -14.988 81.938  1.00 55.25  ? 181 PRO A CA  1 
ATOM   891   C C   . PRO A 1 121 ? -62.428  -14.399 81.420  1.00 56.63  ? 181 PRO A C   1 
ATOM   892   O O   . PRO A 1 121 ? -62.108  -13.272 81.770  1.00 64.47  ? 181 PRO A O   1 
ATOM   893   C CB  . PRO A 1 121 ? -63.655  -15.469 83.407  1.00 51.51  ? 181 PRO A CB  1 
ATOM   894   C CG  . PRO A 1 121 ? -64.318  -16.852 83.434  1.00 49.14  ? 181 PRO A CG  1 
ATOM   895   C CD  . PRO A 1 121 ? -64.201  -17.394 82.019  1.00 52.59  ? 181 PRO A CD  1 
ATOM   896   N N   . PHE A 1 122 ? -61.672  -15.166 80.627  1.00 56.42  ? 182 PHE A N   1 
ATOM   897   C CA  . PHE A 1 122 ? -60.315  -14.805 80.132  1.00 57.47  ? 182 PHE A CA  1 
ATOM   898   C C   . PHE A 1 122 ? -60.398  -14.134 78.752  1.00 55.64  ? 182 PHE A C   1 
ATOM   899   O O   . PHE A 1 122 ? -59.708  -13.124 78.577  1.00 61.34  ? 182 PHE A O   1 
ATOM   900   C CB  . PHE A 1 122 ? -59.402  -16.029 80.128  1.00 57.79  ? 182 PHE A CB  1 
ATOM   901   C CG  . PHE A 1 122 ? -59.191  -16.630 81.491  1.00 63.14  ? 182 PHE A CG  1 
ATOM   902   C CD1 . PHE A 1 122 ? -58.813  -15.844 82.579  1.00 55.51  ? 182 PHE A CD1 1 
ATOM   903   C CD2 . PHE A 1 122 ? -59.335  -17.998 81.679  1.00 63.35  ? 182 PHE A CD2 1 
ATOM   904   C CE1 . PHE A 1 122 ? -58.603  -16.414 83.825  1.00 55.66  ? 182 PHE A CE1 1 
ATOM   905   C CE2 . PHE A 1 122 ? -59.091  -18.571 82.927  1.00 62.17  ? 182 PHE A CE2 1 
ATOM   906   C CZ  . PHE A 1 122 ? -58.742  -17.777 84.001  1.00 57.45  ? 182 PHE A CZ  1 
ATOM   907   N N   . VAL A 1 123 ? -61.238  -14.637 77.840  1.00 53.19  ? 183 VAL A N   1 
ATOM   908   C CA  . VAL A 1 123 ? -61.457  -14.063 76.474  1.00 53.91  ? 183 VAL A CA  1 
ATOM   909   C C   . VAL A 1 123 ? -62.498  -12.930 76.513  1.00 51.80  ? 183 VAL A C   1 
ATOM   910   O O   . VAL A 1 123 ? -62.456  -12.093 75.614  1.00 45.70  ? 183 VAL A O   1 
ATOM   911   C CB  . VAL A 1 123 ? -61.859  -15.177 75.482  1.00 55.55  ? 183 VAL A CB  1 
ATOM   912   C CG1 . VAL A 1 123 ? -60.741  -16.202 75.343  1.00 62.27  ? 183 VAL A CG1 1 
ATOM   913   C CG2 . VAL A 1 123 ? -63.148  -15.890 75.848  1.00 49.97  ? 183 VAL A CG2 1 
ATOM   914   N N   . TYR A 1 124 ? -63.416  -12.961 77.498  1.00 54.72  ? 184 TYR A N   1 
ATOM   915   C CA  . TYR A 1 124 ? -64.591  -12.065 77.682  1.00 51.17  ? 184 TYR A CA  1 
ATOM   916   C C   . TYR A 1 124 ? -64.500  -11.420 79.071  1.00 47.07  ? 184 TYR A C   1 
ATOM   917   O O   . TYR A 1 124 ? -63.436  -11.532 79.696  1.00 50.15  ? 184 TYR A O   1 
ATOM   918   C CB  . TYR A 1 124 ? -65.906  -12.842 77.485  1.00 59.16  ? 184 TYR A CB  1 
ATOM   919   C CG  . TYR A 1 124 ? -67.123  -11.988 77.188  1.00 66.86  ? 184 TYR A CG  1 
ATOM   920   C CD1 . TYR A 1 124 ? -67.028  -10.831 76.412  1.00 67.17  ? 184 TYR A CD1 1 
ATOM   921   C CD2 . TYR A 1 124 ? -68.370  -12.314 77.702  1.00 62.74  ? 184 TYR A CD2 1 
ATOM   922   C CE1 . TYR A 1 124 ? -68.120  -10.026 76.155  1.00 61.35  ? 184 TYR A CE1 1 
ATOM   923   C CE2 . TYR A 1 124 ? -69.472  -11.510 77.464  1.00 63.90  ? 184 TYR A CE2 1 
ATOM   924   C CZ  . TYR A 1 124 ? -69.346  -10.371 76.685  1.00 68.28  ? 184 TYR A CZ  1 
ATOM   925   O OH  . TYR A 1 124 ? -70.418  -9.563  76.432  1.00 91.96  ? 184 TYR A OH  1 
ATOM   926   N N   . THR A 1 125 ? -65.557  -10.750 79.542  1.00 44.28  ? 185 THR A N   1 
ATOM   927   C CA  . THR A 1 125 ? -65.585  -10.091 80.874  1.00 47.89  ? 185 THR A CA  1 
ATOM   928   C C   . THR A 1 125 ? -65.254  -11.123 81.958  1.00 49.01  ? 185 THR A C   1 
ATOM   929   O O   . THR A 1 125 ? -65.815  -12.227 81.967  1.00 49.79  ? 185 THR A O   1 
ATOM   930   C CB  . THR A 1 125 ? -66.908  -9.355  81.136  1.00 55.46  ? 185 THR A CB  1 
ATOM   931   O OG1 . THR A 1 125 ? -66.797  -8.599  82.352  1.00 57.76  ? 185 THR A OG1 1 
ATOM   932   C CG2 . THR A 1 125 ? -68.092  -10.297 81.225  1.00 54.18  ? 185 THR A CG2 1 
ATOM   933   N N   . PRO A 1 126 ? -64.349  -10.800 82.921  1.00 47.38  ? 186 PRO A N   1 
ATOM   934   C CA  . PRO A 1 126 ? -63.764  -9.452  83.083  1.00 49.27  ? 186 PRO A CA  1 
ATOM   935   C C   . PRO A 1 126 ? -62.386  -9.118  82.461  1.00 57.15  ? 186 PRO A C   1 
ATOM   936   O O   . PRO A 1 126 ? -62.038  -7.922  82.342  1.00 50.50  ? 186 PRO A O   1 
ATOM   937   C CB  . PRO A 1 126 ? -63.589  -9.404  84.600  1.00 45.18  ? 186 PRO A CB  1 
ATOM   938   C CG  . PRO A 1 126 ? -63.134  -10.798 84.916  1.00 50.03  ? 186 PRO A CG  1 
ATOM   939   C CD  . PRO A 1 126 ? -63.899  -11.717 83.974  1.00 48.66  ? 186 PRO A CD  1 
ATOM   940   N N   . THR A 1 127 ? -61.633  -10.158 82.073  1.00 50.46  ? 187 THR A N   1 
ATOM   941   C CA  . THR A 1 127 ? -60.245  -10.057 81.570  1.00 45.97  ? 187 THR A CA  1 
ATOM   942   C C   . THR A 1 127 ? -60.169  -9.071  80.396  1.00 43.59  ? 187 THR A C   1 
ATOM   943   O O   . THR A 1 127 ? -59.211  -8.286  80.328  1.00 32.75  ? 187 THR A O   1 
ATOM   944   C CB  . THR A 1 127 ? -59.749  -11.436 81.140  1.00 42.38  ? 187 THR A CB  1 
ATOM   945   O OG1 . THR A 1 127 ? -59.843  -12.295 82.273  1.00 38.65  ? 187 THR A OG1 1 
ATOM   946   C CG2 . THR A 1 127 ? -58.328  -11.379 80.642  1.00 47.32  ? 187 THR A CG2 1 
ATOM   947   N N   . VAL A 1 128 ? -61.148  -9.164  79.500  1.00 45.05  ? 188 VAL A N   1 
ATOM   948   C CA  . VAL A 1 128 ? -61.206  -8.439  78.200  1.00 46.48  ? 188 VAL A CA  1 
ATOM   949   C C   . VAL A 1 128 ? -61.187  -6.929  78.487  1.00 48.12  ? 188 VAL A C   1 
ATOM   950   O O   . VAL A 1 128 ? -60.932  -6.137  77.572  1.00 45.72  ? 188 VAL A O   1 
ATOM   951   C CB  . VAL A 1 128 ? -62.460  -8.882  77.428  1.00 44.77  ? 188 VAL A CB  1 
ATOM   952   C CG1 . VAL A 1 128 ? -63.730  -8.336  78.068  1.00 46.12  ? 188 VAL A CG1 1 
ATOM   953   C CG2 . VAL A 1 128 ? -62.411  -8.500  75.973  1.00 49.73  ? 188 VAL A CG2 1 
ATOM   954   N N   . GLY A 1 129 ? -61.507  -6.549  79.721  1.00 50.44  ? 189 GLY A N   1 
ATOM   955   C CA  . GLY A 1 129 ? -61.501  -5.147  80.154  1.00 46.89  ? 189 GLY A CA  1 
ATOM   956   C C   . GLY A 1 129 ? -60.086  -4.685  80.353  1.00 45.89  ? 189 GLY A C   1 
ATOM   957   O O   . GLY A 1 129 ? -59.747  -3.649  79.800  1.00 46.68  ? 189 GLY A O   1 
ATOM   958   N N   . GLU A 1 130 ? -59.308  -5.424  81.143  1.00 49.47  ? 190 GLU A N   1 
ATOM   959   C CA  . GLU A 1 130 ? -57.860  -5.178  81.378  1.00 54.52  ? 190 GLU A CA  1 
ATOM   960   C C   . GLU A 1 130 ? -57.150  -5.158  80.014  1.00 60.80  ? 190 GLU A C   1 
ATOM   961   O O   . GLU A 1 130 ? -56.379  -4.206  79.743  1.00 62.52  ? 190 GLU A O   1 
ATOM   962   C CB  . GLU A 1 130 ? -57.296  -6.251  82.318  1.00 52.90  ? 190 GLU A CB  1 
ATOM   963   C CG  . GLU A 1 130 ? -55.805  -6.143  82.500  1.00 57.88  ? 190 GLU A CG  1 
ATOM   964   C CD  . GLU A 1 130 ? -55.137  -6.982  83.583  1.00 64.21  ? 190 GLU A CD  1 
ATOM   965   O OE1 . GLU A 1 130 ? -55.365  -8.225  83.668  1.00 77.19  ? 190 GLU A OE1 1 
ATOM   966   O OE2 . GLU A 1 130 ? -54.324  -6.397  84.308  1.00 67.32  ? 190 GLU A OE2 1 
ATOM   967   N N   . ALA A 1 131 ? -57.429  -6.155  79.168  1.00 62.02  ? 191 ALA A N   1 
ATOM   968   C CA  . ALA A 1 131 ? -56.847  -6.267  77.811  1.00 59.12  ? 191 ALA A CA  1 
ATOM   969   C C   . ALA A 1 131 ? -57.046  -4.927  77.108  1.00 49.56  ? 191 ALA A C   1 
ATOM   970   O O   . ALA A 1 131 ? -56.101  -4.464  76.507  1.00 57.40  ? 191 ALA A O   1 
ATOM   971   C CB  . ALA A 1 131 ? -57.424  -7.419  77.009  1.00 54.28  ? 191 ALA A CB  1 
ATOM   972   N N   . CYS A 1 132 ? -58.209  -4.299  77.213  1.00 48.24  ? 192 CYS A N   1 
ATOM   973   C CA  . CYS A 1 132 ? -58.499  -3.013  76.514  1.00 50.26  ? 192 CYS A CA  1 
ATOM   974   C C   . CYS A 1 132 ? -57.726  -1.856  77.161  1.00 47.95  ? 192 CYS A C   1 
ATOM   975   O O   . CYS A 1 132 ? -57.352  -0.918  76.448  1.00 54.23  ? 192 CYS A O   1 
ATOM   976   C CB  . CYS A 1 132 ? -59.982  -2.676  76.487  1.00 50.00  ? 192 CYS A CB  1 
ATOM   977   S SG  . CYS A 1 132 ? -60.918  -3.625  75.263  1.00 50.85  ? 192 CYS A SG  1 
ATOM   978   N N   . GLN A 1 133 ? -57.493  -1.909  78.462  1.00 42.98  ? 193 GLN A N   1 
ATOM   979   C CA  . GLN A 1 133 ? -56.822  -0.807  79.175  1.00 49.09  ? 193 GLN A CA  1 
ATOM   980   C C   . GLN A 1 133 ? -55.340  -0.806  78.803  1.00 54.56  ? 193 GLN A C   1 
ATOM   981   O O   . GLN A 1 133 ? -54.726  0.301   78.759  1.00 48.75  ? 193 GLN A O   1 
ATOM   982   C CB  . GLN A 1 133 ? -57.014  -0.976  80.676  1.00 51.14  ? 193 GLN A CB  1 
ATOM   983   C CG  . GLN A 1 133 ? -58.377  -0.523  81.147  1.00 53.72  ? 193 GLN A CG  1 
ATOM   984   C CD  . GLN A 1 133 ? -58.563  -0.842  82.607  1.00 55.18  ? 193 GLN A CD  1 
ATOM   985   O OE1 . GLN A 1 133 ? -58.410  -1.985  83.025  1.00 60.45  ? 193 GLN A OE1 1 
ATOM   986   N NE2 . GLN A 1 133 ? -58.906  0.166   83.390  1.00 58.01  ? 193 GLN A NE2 1 
ATOM   987   N N   . LYS A 1 134 ? -54.802  -2.005  78.553  1.00 58.32  ? 194 LYS A N   1 
ATOM   988   C CA  . LYS A 1 134 ? -53.357  -2.250  78.309  1.00 61.64  ? 194 LYS A CA  1 
ATOM   989   C C   . LYS A 1 134 ? -53.144  -2.753  76.872  1.00 54.98  ? 194 LYS A C   1 
ATOM   990   O O   . LYS A 1 134 ? -52.135  -3.405  76.641  1.00 55.25  ? 194 LYS A O   1 
ATOM   991   C CB  . LYS A 1 134 ? -52.805  -3.283  79.310  1.00 65.41  ? 194 LYS A CB  1 
ATOM   992   C CG  . LYS A 1 134 ? -53.100  -3.069  80.793  1.00 68.98  ? 194 LYS A CG  1 
ATOM   993   C CD  . LYS A 1 134 ? -52.009  -2.398  81.629  1.00 76.24  ? 194 LYS A CD  1 
ATOM   994   C CE  . LYS A 1 134 ? -52.372  -2.360  83.096  1.00 73.33  ? 194 LYS A CE  1 
ATOM   995   N NZ  . LYS A 1 134 ? -52.655  -3.722  83.621  1.00 71.19  ? 194 LYS A NZ  1 
ATOM   996   N N   . TYR A 1 135 ? -54.042  -2.457  75.933  1.00 56.64  ? 195 TYR A N   1 
ATOM   997   C CA  . TYR A 1 135 ? -54.036  -3.048  74.568  1.00 57.15  ? 195 TYR A CA  1 
ATOM   998   C C   . TYR A 1 135 ? -52.729  -2.681  73.871  1.00 61.41  ? 195 TYR A C   1 
ATOM   999   O O   . TYR A 1 135 ? -52.104  -3.553  73.252  1.00 60.90  ? 195 TYR A O   1 
ATOM   1000  C CB  . TYR A 1 135 ? -55.236  -2.563  73.743  1.00 52.61  ? 195 TYR A CB  1 
ATOM   1001  C CG  . TYR A 1 135 ? -55.756  -3.571  72.746  1.00 53.28  ? 195 TYR A CG  1 
ATOM   1002  C CD1 . TYR A 1 135 ? -56.257  -4.807  73.173  1.00 54.49  ? 195 TYR A CD1 1 
ATOM   1003  C CD2 . TYR A 1 135 ? -55.784  -3.295  71.393  1.00 44.57  ? 195 TYR A CD2 1 
ATOM   1004  C CE1 . TYR A 1 135 ? -56.785  -5.738  72.293  1.00 48.84  ? 195 TYR A CE1 1 
ATOM   1005  C CE2 . TYR A 1 135 ? -56.305  -4.214  70.495  1.00 45.33  ? 195 TYR A CE2 1 
ATOM   1006  C CZ  . TYR A 1 135 ? -56.805  -5.431  70.948  1.00 49.43  ? 195 TYR A CZ  1 
ATOM   1007  O OH  . TYR A 1 135 ? -57.346  -6.352  70.102  1.00 57.13  ? 195 TYR A OH  1 
ATOM   1008  N N   . GLY A 1 136 ? -52.334  -1.412  73.997  1.00 68.20  ? 196 GLY A N   1 
ATOM   1009  C CA  . GLY A 1 136 ? -51.150  -0.838  73.337  1.00 68.16  ? 196 GLY A CA  1 
ATOM   1010  C C   . GLY A 1 136 ? -49.867  -1.537  73.735  1.00 67.02  ? 196 GLY A C   1 
ATOM   1011  O O   . GLY A 1 136 ? -48.997  -1.682  72.875  1.00 81.40  ? 196 GLY A O   1 
ATOM   1012  N N   . SER A 1 137 ? -49.754  -1.965  74.992  1.00 60.53  ? 197 SER A N   1 
ATOM   1013  C CA  . SER A 1 137 ? -48.513  -2.520  75.579  1.00 61.29  ? 197 SER A CA  1 
ATOM   1014  C C   . SER A 1 137 ? -48.468  -4.053  75.428  1.00 58.31  ? 197 SER A C   1 
ATOM   1015  O O   . SER A 1 137 ? -47.426  -4.639  75.729  1.00 55.24  ? 197 SER A O   1 
ATOM   1016  C CB  . SER A 1 137 ? -48.399  -2.081  77.011  1.00 63.94  ? 197 SER A CB  1 
ATOM   1017  O OG  . SER A 1 137 ? -49.318  -2.793  77.824  1.00 59.30  ? 197 SER A OG  1 
ATOM   1018  N N   . ILE A 1 138 ? -49.545  -4.666  74.940  1.00 62.07  ? 198 ILE A N   1 
ATOM   1019  C CA  . ILE A 1 138 ? -49.722  -6.145  74.843  1.00 67.62  ? 198 ILE A CA  1 
ATOM   1020  C C   . ILE A 1 138 ? -49.179  -6.585  73.487  1.00 76.12  ? 198 ILE A C   1 
ATOM   1021  O O   . ILE A 1 138 ? -49.335  -5.815  72.502  1.00 55.44  ? 198 ILE A O   1 
ATOM   1022  C CB  . ILE A 1 138 ? -51.209  -6.557  75.050  1.00 68.89  ? 198 ILE A CB  1 
ATOM   1023  C CG1 . ILE A 1 138 ? -51.606  -6.719  76.520  1.00 69.02  ? 198 ILE A CG1 1 
ATOM   1024  C CG2 . ILE A 1 138 ? -51.616  -7.793  74.273  1.00 75.76  ? 198 ILE A CG2 1 
ATOM   1025  C CD1 . ILE A 1 138 ? -50.462  -6.811  77.522  1.00 75.23  ? 198 ILE A CD1 1 
ATOM   1026  N N   . PHE A 1 139 ? -48.571  -7.778  73.488  1.00 109.33 ? 199 PHE A N   1 
ATOM   1027  C CA  . PHE A 1 139 ? -47.994  -8.455  72.296  1.00 124.07 ? 199 PHE A CA  1 
ATOM   1028  C C   . PHE A 1 139 ? -49.120  -8.664  71.286  1.00 127.52 ? 199 PHE A C   1 
ATOM   1029  O O   . PHE A 1 139 ? -50.097  -9.359  71.608  1.00 119.14 ? 199 PHE A O   1 
ATOM   1030  C CB  . PHE A 1 139 ? -47.281  -9.764  72.653  1.00 123.75 ? 199 PHE A CB  1 
ATOM   1031  C CG  . PHE A 1 139 ? -46.775  -10.476 71.426  1.00 131.91 ? 199 PHE A CG  1 
ATOM   1032  C CD1 . PHE A 1 139 ? -45.793  -9.893  70.627  1.00 118.75 ? 199 PHE A CD1 1 
ATOM   1033  C CD2 . PHE A 1 139 ? -47.343  -11.671 71.018  1.00 127.36 ? 199 PHE A CD2 1 
ATOM   1034  C CE1 . PHE A 1 139 ? -45.350  -10.526 69.477  1.00 114.92 ? 199 PHE A CE1 1 
ATOM   1035  C CE2 . PHE A 1 139 ? -46.884  -12.313 69.873  1.00 129.71 ? 199 PHE A CE2 1 
ATOM   1036  C CZ  . PHE A 1 139 ? -45.889  -11.740 69.107  1.00 122.27 ? 199 PHE A CZ  1 
ATOM   1037  N N   . ARG A 1 140 ? -48.967  -8.080  70.095  1.00 138.82 ? 200 ARG A N   1 
ATOM   1038  C CA  . ARG A 1 140 ? -50.080  -7.765  69.161  1.00 145.37 ? 200 ARG A CA  1 
ATOM   1039  C C   . ARG A 1 140 ? -49.863  -8.521  67.845  1.00 126.20 ? 200 ARG A C   1 
ATOM   1040  O O   . ARG A 1 140 ? -49.061  -8.063  67.015  1.00 107.68 ? 200 ARG A O   1 
ATOM   1041  C CB  . ARG A 1 140 ? -50.197  -6.240  68.952  1.00 141.07 ? 200 ARG A CB  1 
ATOM   1042  C CG  . ARG A 1 140 ? -48.994  -5.388  69.370  1.00 113.71 ? 200 ARG A CG  1 
ATOM   1043  C CD  . ARG A 1 140 ? -47.735  -5.541  68.505  1.00 112.79 ? 200 ARG A CD  1 
ATOM   1044  N NE  . ARG A 1 140 ? -46.666  -4.574  68.760  1.00 89.22  ? 200 ARG A NE  1 
ATOM   1045  C CZ  . ARG A 1 140 ? -45.843  -4.073  67.850  1.00 64.41  ? 200 ARG A CZ  1 
ATOM   1046  N NH1 . ARG A 1 140 ? -45.935  -4.408  66.580  1.00 61.54  ? 200 ARG A NH1 1 
ATOM   1047  N NH2 . ARG A 1 140 ? -44.947  -3.191  68.213  1.00 70.58  ? 200 ARG A NH2 1 
ATOM   1048  N N   . ARG A 1 141 ? -50.536  -9.661  67.686  1.00 110.79 ? 201 ARG A N   1 
ATOM   1049  C CA  . ARG A 1 141 ? -50.876  -10.212 66.348  1.00 114.90 ? 201 ARG A CA  1 
ATOM   1050  C C   . ARG A 1 141 ? -52.127  -9.430  65.930  1.00 107.31 ? 201 ARG A C   1 
ATOM   1051  O O   . ARG A 1 141 ? -53.066  -9.331  66.717  1.00 122.16 ? 201 ARG A O   1 
ATOM   1052  C CB  . ARG A 1 141 ? -51.024  -11.742 66.423  1.00 114.74 ? 201 ARG A CB  1 
ATOM   1053  C CG  . ARG A 1 141 ? -49.719  -12.532 66.274  1.00 115.31 ? 201 ARG A CG  1 
ATOM   1054  C CD  . ARG A 1 141 ? -49.646  -13.491 65.092  1.00 123.79 ? 201 ARG A CD  1 
ATOM   1055  N NE  . ARG A 1 141 ? -50.539  -13.061 64.016  1.00 138.50 ? 201 ARG A NE  1 
ATOM   1056  C CZ  . ARG A 1 141 ? -50.214  -12.273 62.988  1.00 134.64 ? 201 ARG A CZ  1 
ATOM   1057  N NH1 . ARG A 1 141 ? -48.974  -11.835 62.836  1.00 128.87 ? 201 ARG A NH1 1 
ATOM   1058  N NH2 . ARG A 1 141 ? -51.139  -11.947 62.097  1.00 129.00 ? 201 ARG A NH2 1 
ATOM   1059  N N   . PRO A 1 142 ? -52.183  -8.775  64.742  1.00 90.48  ? 202 PRO A N   1 
ATOM   1060  C CA  . PRO A 1 142 ? -53.369  -7.999  64.351  1.00 77.36  ? 202 PRO A CA  1 
ATOM   1061  C C   . PRO A 1 142 ? -54.675  -8.817  64.195  1.00 73.31  ? 202 PRO A C   1 
ATOM   1062  O O   . PRO A 1 142 ? -54.710  -9.946  63.712  1.00 61.61  ? 202 PRO A O   1 
ATOM   1063  C CB  . PRO A 1 142 ? -52.957  -7.313  63.038  1.00 77.47  ? 202 PRO A CB  1 
ATOM   1064  C CG  . PRO A 1 142 ? -51.775  -8.124  62.514  1.00 81.87  ? 202 PRO A CG  1 
ATOM   1065  C CD  . PRO A 1 142 ? -51.116  -8.731  63.731  1.00 83.47  ? 202 PRO A CD  1 
ATOM   1066  N N   . GLN A 1 143 ? -55.767  -8.219  64.673  1.00 81.72  ? 203 GLN A N   1 
ATOM   1067  C CA  . GLN A 1 143 ? -57.168  -8.705  64.518  1.00 77.21  ? 203 GLN A CA  1 
ATOM   1068  C C   . GLN A 1 143 ? -58.091  -7.499  64.306  1.00 67.28  ? 203 GLN A C   1 
ATOM   1069  O O   . GLN A 1 143 ? -57.857  -6.413  64.920  1.00 57.43  ? 203 GLN A O   1 
ATOM   1070  C CB  . GLN A 1 143 ? -57.625  -9.495  65.748  1.00 74.19  ? 203 GLN A CB  1 
ATOM   1071  C CG  . GLN A 1 143 ? -56.524  -10.196 66.540  1.00 70.24  ? 203 GLN A CG  1 
ATOM   1072  C CD  . GLN A 1 143 ? -57.115  -11.179 67.509  1.00 60.43  ? 203 GLN A CD  1 
ATOM   1073  O OE1 . GLN A 1 143 ? -58.237  -11.056 67.941  1.00 67.00  ? 203 GLN A OE1 1 
ATOM   1074  N NE2 . GLN A 1 143 ? -56.397  -12.241 67.786  1.00 74.99  ? 203 GLN A NE2 1 
ATOM   1075  N N   . GLY A 1 144 ? -59.085  -7.656  63.442  1.00 58.18  ? 204 GLY A N   1 
ATOM   1076  C CA  . GLY A 1 144 ? -60.069  -6.585  63.200  1.00 58.50  ? 204 GLY A CA  1 
ATOM   1077  C C   . GLY A 1 144 ? -59.523  -5.454  62.343  1.00 51.91  ? 204 GLY A C   1 
ATOM   1078  O O   . GLY A 1 144 ? -58.320  -5.444  62.004  1.00 60.37  ? 204 GLY A O   1 
ATOM   1079  N N   . LEU A 1 145 ? -60.391  -4.514  62.022  1.00 41.27  ? 205 LEU A N   1 
ATOM   1080  C CA  . LEU A 1 145 ? -60.108  -3.417  61.088  1.00 46.80  ? 205 LEU A CA  1 
ATOM   1081  C C   . LEU A 1 145 ? -60.291  -2.078  61.807  1.00 38.79  ? 205 LEU A C   1 
ATOM   1082  O O   . LEU A 1 145 ? -61.305  -1.910  62.459  1.00 34.38  ? 205 LEU A O   1 
ATOM   1083  C CB  . LEU A 1 145 ? -61.093  -3.589  59.932  1.00 56.50  ? 205 LEU A CB  1 
ATOM   1084  C CG  . LEU A 1 145 ? -60.754  -2.850  58.640  1.00 70.62  ? 205 LEU A CG  1 
ATOM   1085  C CD1 . LEU A 1 145 ? -61.087  -3.710  57.430  1.00 81.36  ? 205 LEU A CD1 1 
ATOM   1086  C CD2 . LEU A 1 145 ? -61.500  -1.517  58.546  1.00 73.11  ? 205 LEU A CD2 1 
ATOM   1087  N N   . TYR A 1 146 ? -59.362  -1.147  61.657  1.00 39.27  ? 206 TYR A N   1 
ATOM   1088  C CA  . TYR A 1 146 ? -59.433  0.199   62.283  1.00 43.32  ? 206 TYR A CA  1 
ATOM   1089  C C   . TYR A 1 146 ? -59.707  1.227   61.197  1.00 37.69  ? 206 TYR A C   1 
ATOM   1090  O O   . TYR A 1 146 ? -58.888  1.387   60.288  1.00 39.52  ? 206 TYR A O   1 
ATOM   1091  C CB  . TYR A 1 146 ? -58.143  0.547   63.040  1.00 49.79  ? 206 TYR A CB  1 
ATOM   1092  C CG  . TYR A 1 146 ? -57.680  -0.468  64.063  1.00 51.77  ? 206 TYR A CG  1 
ATOM   1093  C CD1 . TYR A 1 146 ? -57.187  -1.707  63.659  1.00 52.65  ? 206 TYR A CD1 1 
ATOM   1094  C CD2 . TYR A 1 146 ? -57.740  -0.202  65.423  1.00 43.41  ? 206 TYR A CD2 1 
ATOM   1095  C CE1 . TYR A 1 146 ? -56.773  -2.662  64.568  1.00 47.58  ? 206 TYR A CE1 1 
ATOM   1096  C CE2 . TYR A 1 146 ? -57.306  -1.136  66.349  1.00 46.27  ? 206 TYR A CE2 1 
ATOM   1097  C CZ  . TYR A 1 146 ? -56.823  -2.363  65.916  1.00 49.61  ? 206 TYR A CZ  1 
ATOM   1098  O OH  . TYR A 1 146 ? -56.394  -3.313  66.786  1.00 59.86  ? 206 TYR A OH  1 
ATOM   1099  N N   . VAL A 1 147 ? -60.823  1.926   61.317  1.00 39.32  ? 207 VAL A N   1 
ATOM   1100  C CA  . VAL A 1 147 ? -61.165  3.104   60.454  1.00 45.11  ? 207 VAL A CA  1 
ATOM   1101  C C   . VAL A 1 147 ? -60.917  4.400   61.226  1.00 40.96  ? 207 VAL A C   1 
ATOM   1102  O O   . VAL A 1 147 ? -61.641  4.657   62.186  1.00 39.82  ? 207 VAL A O   1 
ATOM   1103  C CB  . VAL A 1 147 ? -62.627  3.024   59.996  1.00 44.69  ? 207 VAL A CB  1 
ATOM   1104  C CG1 . VAL A 1 147 ? -63.046  4.265   59.214  1.00 41.93  ? 207 VAL A CG1 1 
ATOM   1105  C CG2 . VAL A 1 147 ? -62.870  1.733   59.225  1.00 44.64  ? 207 VAL A CG2 1 
ATOM   1106  N N   . SER A 1 148 ? -59.903  5.164   60.852  1.00 44.36  ? 208 SER A N   1 
ATOM   1107  C CA  . SER A 1 148 ? -59.550  6.408   61.597  1.00 54.66  ? 208 SER A CA  1 
ATOM   1108  C C   . SER A 1 148 ? -60.247  7.596   60.947  1.00 52.70  ? 208 SER A C   1 
ATOM   1109  O O   . SER A 1 148 ? -60.869  7.416   59.888  1.00 44.14  ? 208 SER A O   1 
ATOM   1110  C CB  . SER A 1 148 ? -58.068  6.651   61.688  1.00 53.80  ? 208 SER A CB  1 
ATOM   1111  O OG  . SER A 1 148 ? -57.547  7.029   60.421  1.00 60.88  ? 208 SER A OG  1 
ATOM   1112  N N   . LEU A 1 149 ? -60.132  8.753   61.598  1.00 58.42  ? 209 LEU A N   1 
ATOM   1113  C CA  . LEU A 1 149 ? -60.548  10.073  61.057  1.00 58.14  ? 209 LEU A CA  1 
ATOM   1114  C C   . LEU A 1 149 ? -59.785  10.372  59.770  1.00 53.07  ? 209 LEU A C   1 
ATOM   1115  O O   . LEU A 1 149 ? -60.262  11.165  58.964  1.00 59.69  ? 209 LEU A O   1 
ATOM   1116  C CB  . LEU A 1 149 ? -60.243  11.140  62.108  1.00 59.71  ? 209 LEU A CB  1 
ATOM   1117  C CG  . LEU A 1 149 ? -61.459  11.705  62.821  1.00 62.87  ? 209 LEU A CG  1 
ATOM   1118  C CD1 . LEU A 1 149 ? -61.019  12.445  64.066  1.00 73.34  ? 209 LEU A CD1 1 
ATOM   1119  C CD2 . LEU A 1 149 ? -62.208  12.636  61.881  1.00 64.99  ? 209 LEU A CD2 1 
ATOM   1120  N N   . LYS A 1 150 ? -58.609  9.783   59.614  1.00 56.76  ? 210 LYS A N   1 
ATOM   1121  C CA  . LYS A 1 150 ? -57.714  10.062  58.471  1.00 62.96  ? 210 LYS A CA  1 
ATOM   1122  C C   . LYS A 1 150 ? -58.058  9.126   57.309  1.00 54.12  ? 210 LYS A C   1 
ATOM   1123  O O   . LYS A 1 150 ? -57.324  9.171   56.322  1.00 55.26  ? 210 LYS A O   1 
ATOM   1124  C CB  . LYS A 1 150 ? -56.249  9.927   58.909  1.00 69.32  ? 210 LYS A CB  1 
ATOM   1125  C CG  . LYS A 1 150 ? -55.809  10.816  60.063  1.00 81.48  ? 210 LYS A CG  1 
ATOM   1126  C CD  . LYS A 1 150 ? -54.295  10.923  60.214  1.00 92.09  ? 210 LYS A CD  1 
ATOM   1127  C CE  . LYS A 1 150 ? -53.737  12.249  59.725  1.00 97.84  ? 210 LYS A CE  1 
ATOM   1128  N NZ  . LYS A 1 150 ? -53.762  13.303  60.773  1.00 95.43  ? 210 LYS A NZ  1 
ATOM   1129  N N   . ASP A 1 151 ? -59.137  8.341   57.410  1.00 57.72  ? 211 ASP A N   1 
ATOM   1130  C CA  . ASP A 1 151 ? -59.608  7.418   56.344  1.00 63.59  ? 211 ASP A CA  1 
ATOM   1131  C C   . ASP A 1 151 ? -60.891  8.012   55.721  1.00 64.28  ? 211 ASP A C   1 
ATOM   1132  O O   . ASP A 1 151 ? -61.552  7.306   54.920  1.00 62.13  ? 211 ASP A O   1 
ATOM   1133  C CB  . ASP A 1 151 ? -59.728  5.986   56.893  1.00 67.56  ? 211 ASP A CB  1 
ATOM   1134  C CG  . ASP A 1 151 ? -58.446  5.425   57.499  1.00 68.38  ? 211 ASP A CG  1 
ATOM   1135  O OD1 . ASP A 1 151 ? -57.389  5.647   56.895  1.00 71.97  ? 211 ASP A OD1 1 
ATOM   1136  O OD2 . ASP A 1 151 ? -58.510  4.751   58.578  1.00 71.36  ? 211 ASP A OD2 1 
ATOM   1137  N N   . LYS A 1 152 ? -61.192  9.284   55.995  1.00 64.32  ? 212 LYS A N   1 
ATOM   1138  C CA  . LYS A 1 152 ? -62.349  10.000  55.405  1.00 70.30  ? 212 LYS A CA  1 
ATOM   1139  C C   . LYS A 1 152 ? -62.125  10.249  53.926  1.00 66.18  ? 212 LYS A C   1 
ATOM   1140  O O   . LYS A 1 152 ? -61.027  10.619  53.587  1.00 69.64  ? 212 LYS A O   1 
ATOM   1141  C CB  . LYS A 1 152 ? -62.521  11.397  55.987  1.00 76.54  ? 212 LYS A CB  1 
ATOM   1142  C CG  . LYS A 1 152 ? -63.120  11.463  57.374  1.00 99.02  ? 212 LYS A CG  1 
ATOM   1143  C CD  . LYS A 1 152 ? -63.168  12.879  57.907  1.00 111.76 ? 212 LYS A CD  1 
ATOM   1144  C CE  . LYS A 1 152 ? -63.979  13.849  57.070  1.00 103.23 ? 212 LYS A CE  1 
ATOM   1145  N NZ  . LYS A 1 152 ? -65.364  13.364  56.884  1.00 100.78 ? 212 LYS A NZ  1 
ATOM   1146  N N   . GLY A 1 153 ? -63.159  10.056  53.108  1.00 73.41  ? 213 GLY A N   1 
ATOM   1147  C CA  . GLY A 1 153 ? -63.040  9.940   51.648  1.00 80.20  ? 213 GLY A CA  1 
ATOM   1148  C C   . GLY A 1 153 ? -62.684  8.524   51.220  1.00 76.20  ? 213 GLY A C   1 
ATOM   1149  O O   . GLY A 1 153 ? -63.091  8.133   50.116  1.00 93.70  ? 213 GLY A O   1 
ATOM   1150  N N   . LYS A 1 154 ? -61.989  7.754   52.070  1.00 68.02  ? 214 LYS A N   1 
ATOM   1151  C CA  . LYS A 1 154 ? -61.332  6.488   51.664  1.00 72.60  ? 214 LYS A CA  1 
ATOM   1152  C C   . LYS A 1 154 ? -61.731  5.333   52.579  1.00 58.64  ? 214 LYS A C   1 
ATOM   1153  O O   . LYS A 1 154 ? -61.010  4.351   52.607  1.00 58.46  ? 214 LYS A O   1 
ATOM   1154  C CB  . LYS A 1 154 ? -59.819  6.688   51.689  1.00 83.46  ? 214 LYS A CB  1 
ATOM   1155  C CG  . LYS A 1 154 ? -59.316  7.867   50.877  1.00 90.97  ? 214 LYS A CG  1 
ATOM   1156  C CD  . LYS A 1 154 ? -57.800  7.820   50.662  1.00 101.46 ? 214 LYS A CD  1 
ATOM   1157  C CE  . LYS A 1 154 ? -57.267  9.007   49.882  1.00 103.73 ? 214 LYS A CE  1 
ATOM   1158  N NZ  . LYS A 1 154 ? -55.868  9.354   50.261  1.00 101.18 ? 214 LYS A NZ  1 
ATOM   1159  N N   . VAL A 1 155 ? -62.880  5.419   53.238  1.00 54.76  ? 215 VAL A N   1 
ATOM   1160  C CA  . VAL A 1 155 ? -63.362  4.335   54.132  1.00 52.95  ? 215 VAL A CA  1 
ATOM   1161  C C   . VAL A 1 155 ? -63.545  3.070   53.297  1.00 58.23  ? 215 VAL A C   1 
ATOM   1162  O O   . VAL A 1 155 ? -63.258  1.992   53.802  1.00 51.30  ? 215 VAL A O   1 
ATOM   1163  C CB  . VAL A 1 155 ? -64.667  4.720   54.842  1.00 47.95  ? 215 VAL A CB  1 
ATOM   1164  C CG1 . VAL A 1 155 ? -65.285  3.521   55.537  1.00 46.11  ? 215 VAL A CG1 1 
ATOM   1165  C CG2 . VAL A 1 155 ? -64.434  5.866   55.815  1.00 50.27  ? 215 VAL A CG2 1 
ATOM   1166  N N   . LEU A 1 156 ? -64.039  3.199   52.070  1.00 67.41  ? 216 LEU A N   1 
ATOM   1167  C CA  . LEU A 1 156 ? -64.277  2.034   51.189  1.00 71.64  ? 216 LEU A CA  1 
ATOM   1168  C C   . LEU A 1 156 ? -62.943  1.367   50.892  1.00 81.58  ? 216 LEU A C   1 
ATOM   1169  O O   . LEU A 1 156 ? -62.920  0.122   50.869  1.00 91.68  ? 216 LEU A O   1 
ATOM   1170  C CB  . LEU A 1 156 ? -64.922  2.502   49.890  1.00 78.30  ? 216 LEU A CB  1 
ATOM   1171  C CG  . LEU A 1 156 ? -66.349  2.984   50.018  1.00 87.24  ? 216 LEU A CG  1 
ATOM   1172  C CD1 . LEU A 1 156 ? -66.477  4.421   49.497  1.00 87.59  ? 216 LEU A CD1 1 
ATOM   1173  C CD2 . LEU A 1 156 ? -67.265  1.989   49.317  1.00 90.94  ? 216 LEU A CD2 1 
ATOM   1174  N N   . GLU A 1 157 ? -61.910  2.182   50.624  1.00 79.80  ? 217 GLU A N   1 
ATOM   1175  C CA  . GLU A 1 157 ? -60.515  1.735   50.367  1.00 82.42  ? 217 GLU A CA  1 
ATOM   1176  C C   . GLU A 1 157 ? -60.080  0.830   51.526  1.00 78.31  ? 217 GLU A C   1 
ATOM   1177  O O   . GLU A 1 157 ? -59.454  -0.227  51.267  1.00 97.72  ? 217 GLU A O   1 
ATOM   1178  C CB  . GLU A 1 157 ? -59.552  2.918   50.250  1.00 99.74  ? 217 GLU A CB  1 
ATOM   1179  C CG  . GLU A 1 157 ? -59.583  3.642   48.910  1.00 113.32 ? 217 GLU A CG  1 
ATOM   1180  C CD  . GLU A 1 157 ? -58.330  4.454   48.576  1.00 123.98 ? 217 GLU A CD  1 
ATOM   1181  O OE1 . GLU A 1 157 ? -58.257  4.959   47.434  1.00 135.41 ? 217 GLU A OE1 1 
ATOM   1182  O OE2 . GLU A 1 157 ? -57.397  4.543   49.421  1.00 103.04 ? 217 GLU A OE2 1 
ATOM   1183  N N   . VAL A 1 158 ? -60.413  1.219   52.759  1.00 62.21  ? 218 VAL A N   1 
ATOM   1184  C CA  . VAL A 1 158 ? -60.029  0.477   53.997  1.00 57.41  ? 218 VAL A CA  1 
ATOM   1185  C C   . VAL A 1 158 ? -60.819  -0.841  54.028  1.00 56.00  ? 218 VAL A C   1 
ATOM   1186  O O   . VAL A 1 158 ? -60.228  -1.898  54.294  1.00 56.18  ? 218 VAL A O   1 
ATOM   1187  C CB  . VAL A 1 158 ? -60.269  1.321   55.263  1.00 55.46  ? 218 VAL A CB  1 
ATOM   1188  C CG1 . VAL A 1 158 ? -59.880  0.585   56.522  1.00 56.34  ? 218 VAL A CG1 1 
ATOM   1189  C CG2 . VAL A 1 158 ? -59.554  2.656   55.218  1.00 59.08  ? 218 VAL A CG2 1 
ATOM   1190  N N   . LEU A 1 159 ? -62.115  -0.797  53.735  1.00 48.71  ? 219 LEU A N   1 
ATOM   1191  C CA  . LEU A 1 159 ? -62.961  -2.012  53.772  1.00 58.69  ? 219 LEU A CA  1 
ATOM   1192  C C   . LEU A 1 159 ? -62.342  -3.041  52.812  1.00 63.92  ? 219 LEU A C   1 
ATOM   1193  O O   . LEU A 1 159 ? -62.291  -4.263  53.132  1.00 46.56  ? 219 LEU A O   1 
ATOM   1194  C CB  . LEU A 1 159 ? -64.398  -1.622  53.391  1.00 58.89  ? 219 LEU A CB  1 
ATOM   1195  C CG  . LEU A 1 159 ? -65.152  -0.666  54.329  1.00 57.89  ? 219 LEU A CG  1 
ATOM   1196  C CD1 . LEU A 1 159 ? -66.643  -0.706  54.071  1.00 54.39  ? 219 LEU A CD1 1 
ATOM   1197  C CD2 . LEU A 1 159 ? -64.911  -0.949  55.802  1.00 61.03  ? 219 LEU A CD2 1 
ATOM   1198  N N   . ARG A 1 160 ? -61.839  -2.541  51.678  1.00 71.70  ? 220 ARG A N   1 
ATOM   1199  C CA  . ARG A 1 160 ? -61.457  -3.409  50.542  1.00 76.61  ? 220 ARG A CA  1 
ATOM   1200  C C   . ARG A 1 160 ? -60.291  -4.285  50.982  1.00 68.48  ? 220 ARG A C   1 
ATOM   1201  O O   . ARG A 1 160 ? -60.153  -5.382  50.407  1.00 58.77  ? 220 ARG A O   1 
ATOM   1202  C CB  . ARG A 1 160 ? -61.205  -2.608  49.265  1.00 73.40  ? 220 ARG A CB  1 
ATOM   1203  C CG  . ARG A 1 160 ? -59.818  -2.002  49.149  1.00 93.77  ? 220 ARG A CG  1 
ATOM   1204  C CD  . ARG A 1 160 ? -59.213  -1.952  47.751  1.00 102.48 ? 220 ARG A CD  1 
ATOM   1205  N NE  . ARG A 1 160 ? -58.546  -0.653  47.563  1.00 112.97 ? 220 ARG A NE  1 
ATOM   1206  C CZ  . ARG A 1 160 ? -58.108  -0.166  46.409  1.00 111.22 ? 220 ARG A CZ  1 
ATOM   1207  N NH1 . ARG A 1 160 ? -58.207  -0.864  45.285  1.00 106.52 ? 220 ARG A NH1 1 
ATOM   1208  N NH2 . ARG A 1 160 ? -57.553  1.033   46.395  1.00 110.58 ? 220 ARG A NH2 1 
ATOM   1209  N N   . ASN A 1 161 ? -59.528  -3.810  51.971  1.00 56.54  ? 221 ASN A N   1 
ATOM   1210  C CA  . ASN A 1 161 ? -58.287  -4.465  52.456  1.00 56.16  ? 221 ASN A CA  1 
ATOM   1211  C C   . ASN A 1 161 ? -58.645  -5.756  53.203  1.00 52.14  ? 221 ASN A C   1 
ATOM   1212  O O   . ASN A 1 161 ? -57.796  -6.633  53.293  1.00 47.05  ? 221 ASN A O   1 
ATOM   1213  C CB  . ASN A 1 161 ? -57.460  -3.543  53.353  1.00 47.85  ? 221 ASN A CB  1 
ATOM   1214  C CG  . ASN A 1 161 ? -56.697  -2.471  52.605  1.00 47.25  ? 221 ASN A CG  1 
ATOM   1215  O OD1 . ASN A 1 161 ? -56.503  -2.513  51.388  1.00 41.41  ? 221 ASN A OD1 1 
ATOM   1216  N ND2 . ASN A 1 161 ? -56.270  -1.468  53.348  1.00 52.71  ? 221 ASN A ND2 1 
ATOM   1217  N N   . TRP A 1 162 ? -59.851  -5.862  53.746  1.00 51.16  ? 222 TRP A N   1 
ATOM   1218  C CA  . TRP A 1 162 ? -60.253  -7.082  54.481  1.00 51.30  ? 222 TRP A CA  1 
ATOM   1219  C C   . TRP A 1 162 ? -60.366  -8.222  53.472  1.00 44.18  ? 222 TRP A C   1 
ATOM   1220  O O   . TRP A 1 162 ? -61.071  -8.108  52.479  1.00 41.53  ? 222 TRP A O   1 
ATOM   1221  C CB  . TRP A 1 162 ? -61.535  -6.850  55.310  1.00 52.15  ? 222 TRP A CB  1 
ATOM   1222  C CG  . TRP A 1 162 ? -61.840  -7.953  56.281  1.00 53.96  ? 222 TRP A CG  1 
ATOM   1223  C CD1 . TRP A 1 162 ? -62.689  -9.011  56.103  1.00 50.29  ? 222 TRP A CD1 1 
ATOM   1224  C CD2 . TRP A 1 162 ? -61.244  -8.131  57.579  1.00 54.40  ? 222 TRP A CD2 1 
ATOM   1225  N NE1 . TRP A 1 162 ? -62.684  -9.819  57.211  1.00 53.62  ? 222 TRP A NE1 1 
ATOM   1226  C CE2 . TRP A 1 162 ? -61.793  -9.316  58.126  1.00 53.66  ? 222 TRP A CE2 1 
ATOM   1227  C CE3 . TRP A 1 162 ? -60.318  -7.397  58.328  1.00 50.29  ? 222 TRP A CE3 1 
ATOM   1228  C CZ2 . TRP A 1 162 ? -61.443  -9.773  59.396  1.00 54.96  ? 222 TRP A CZ2 1 
ATOM   1229  C CZ3 . TRP A 1 162 ? -59.984  -7.834  59.587  1.00 53.87  ? 222 TRP A CZ3 1 
ATOM   1230  C CH2 . TRP A 1 162 ? -60.530  -9.017  60.102  1.00 62.27  ? 222 TRP A CH2 1 
ATOM   1231  N N   . PRO A 1 163 ? -59.697  -9.366  53.715  1.00 44.63  ? 223 PRO A N   1 
ATOM   1232  C CA  . PRO A 1 163 ? -59.612  -10.436 52.729  1.00 53.14  ? 223 PRO A CA  1 
ATOM   1233  C C   . PRO A 1 163 ? -60.750  -11.466 52.752  1.00 58.14  ? 223 PRO A C   1 
ATOM   1234  O O   . PRO A 1 163 ? -60.499  -12.609 52.380  1.00 63.41  ? 223 PRO A O   1 
ATOM   1235  C CB  . PRO A 1 163 ? -58.300  -11.096 53.173  1.00 55.50  ? 223 PRO A CB  1 
ATOM   1236  C CG  . PRO A 1 163 ? -58.373  -11.050 54.677  1.00 51.43  ? 223 PRO A CG  1 
ATOM   1237  C CD  . PRO A 1 163 ? -59.010  -9.713  54.969  1.00 48.80  ? 223 PRO A CD  1 
ATOM   1238  N N   . HIS A 1 164 ? -61.930  -11.057 53.215  1.00 68.12  ? 224 HIS A N   1 
ATOM   1239  C CA  . HIS A 1 164 ? -63.226  -11.790 53.107  1.00 66.16  ? 224 HIS A CA  1 
ATOM   1240  C C   . HIS A 1 164 ? -64.287  -10.813 52.588  1.00 65.47  ? 224 HIS A C   1 
ATOM   1241  O O   . HIS A 1 164 ? -64.459  -9.703  53.205  1.00 64.19  ? 224 HIS A O   1 
ATOM   1242  C CB  . HIS A 1 164 ? -63.615  -12.451 54.444  1.00 63.00  ? 224 HIS A CB  1 
ATOM   1243  C CG  . HIS A 1 164 ? -62.775  -13.633 54.794  1.00 67.45  ? 224 HIS A CG  1 
ATOM   1244  N ND1 . HIS A 1 164 ? -61.791  -13.568 55.774  1.00 62.60  ? 224 HIS A ND1 1 
ATOM   1245  C CD2 . HIS A 1 164 ? -62.809  -14.920 54.351  1.00 70.67  ? 224 HIS A CD2 1 
ATOM   1246  C CE1 . HIS A 1 164 ? -61.234  -14.766 55.906  1.00 77.44  ? 224 HIS A CE1 1 
ATOM   1247  N NE2 . HIS A 1 164 ? -61.839  -15.618 55.034  1.00 80.30  ? 224 HIS A NE2 1 
ATOM   1248  N N   . ARG A 1 165 ? -64.979  -11.194 51.504  1.00 70.31  ? 225 ARG A N   1 
ATOM   1249  C CA  . ARG A 1 165 ? -65.976  -10.313 50.829  1.00 75.75  ? 225 ARG A CA  1 
ATOM   1250  C C   . ARG A 1 165 ? -67.378  -10.540 51.422  1.00 73.31  ? 225 ARG A C   1 
ATOM   1251  O O   . ARG A 1 165 ? -68.141  -9.542  51.557  1.00 58.34  ? 225 ARG A O   1 
ATOM   1252  C CB  . ARG A 1 165 ? -65.934  -10.482 49.304  1.00 77.94  ? 225 ARG A CB  1 
ATOM   1253  C CG  . ARG A 1 165 ? -66.732  -9.421  48.550  1.00 87.10  ? 225 ARG A CG  1 
ATOM   1254  C CD  . ARG A 1 165 ? -66.603  -7.947  49.008  1.00 81.43  ? 225 ARG A CD  1 
ATOM   1255  N NE  . ARG A 1 165 ? -66.909  -6.968  47.962  1.00 85.52  ? 225 ARG A NE  1 
ATOM   1256  C CZ  . ARG A 1 165 ? -68.113  -6.706  47.432  1.00 77.24  ? 225 ARG A CZ  1 
ATOM   1257  N NH1 . ARG A 1 165 ? -69.194  -7.353  47.833  1.00 76.02  ? 225 ARG A NH1 1 
ATOM   1258  N NH2 . ARG A 1 165 ? -68.218  -5.823  46.453  1.00 78.27  ? 225 ARG A NH2 1 
ATOM   1259  N N   . ASN A 1 166 ? -67.671  -11.781 51.831  1.00 68.01  ? 226 ASN A N   1 
ATOM   1260  C CA  . ASN A 1 166 ? -69.000  -12.254 52.304  1.00 65.83  ? 226 ASN A CA  1 
ATOM   1261  C C   . ASN A 1 166 ? -69.176  -11.967 53.809  1.00 62.58  ? 226 ASN A C   1 
ATOM   1262  O O   . ASN A 1 166 ? -69.144  -12.914 54.604  1.00 71.14  ? 226 ASN A O   1 
ATOM   1263  C CB  . ASN A 1 166 ? -69.133  -13.735 51.934  1.00 72.62  ? 226 ASN A CB  1 
ATOM   1264  C CG  . ASN A 1 166 ? -70.260  -14.480 52.624  1.00 79.77  ? 226 ASN A CG  1 
ATOM   1265  O OD1 . ASN A 1 166 ? -70.027  -15.572 53.154  1.00 82.58  ? 226 ASN A OD1 1 
ATOM   1266  N ND2 . ASN A 1 166 ? -71.454  -13.895 52.658  1.00 72.20  ? 226 ASN A ND2 1 
ATOM   1267  N N   . ILE A 1 167 ? -69.375  -10.710 54.205  1.00 59.71  ? 227 ILE A N   1 
ATOM   1268  C CA  . ILE A 1 167 ? -69.530  -10.320 55.638  1.00 60.94  ? 227 ILE A CA  1 
ATOM   1269  C C   . ILE A 1 167 ? -71.026  -10.292 55.982  1.00 62.08  ? 227 ILE A C   1 
ATOM   1270  O O   . ILE A 1 167 ? -71.791  -9.595  55.250  1.00 71.07  ? 227 ILE A O   1 
ATOM   1271  C CB  . ILE A 1 167 ? -68.824  -8.968  55.910  1.00 60.99  ? 227 ILE A CB  1 
ATOM   1272  C CG1 . ILE A 1 167 ? -67.312  -9.116  55.766  1.00 65.29  ? 227 ILE A CG1 1 
ATOM   1273  C CG2 . ILE A 1 167 ? -69.202  -8.411  57.282  1.00 59.45  ? 227 ILE A CG2 1 
ATOM   1274  C CD1 . ILE A 1 167 ? -66.745  -10.335 56.521  1.00 70.76  ? 227 ILE A CD1 1 
ATOM   1275  N N   . GLN A 1 168 ? -71.414  -11.012 57.046  1.00 55.95  ? 228 GLN A N   1 
ATOM   1276  C CA  . GLN A 1 168 ? -72.810  -11.135 57.556  1.00 58.42  ? 228 GLN A CA  1 
ATOM   1277  C C   . GLN A 1 168 ? -72.985  -10.367 58.879  1.00 60.11  ? 228 GLN A C   1 
ATOM   1278  O O   . GLN A 1 168 ? -74.052  -9.779  59.064  1.00 66.97  ? 228 GLN A O   1 
ATOM   1279  C CB  . GLN A 1 168 ? -73.155  -12.616 57.763  1.00 59.34  ? 228 GLN A CB  1 
ATOM   1280  C CG  . GLN A 1 168 ? -73.246  -13.407 56.462  1.00 61.91  ? 228 GLN A CG  1 
ATOM   1281  C CD  . GLN A 1 168 ? -73.887  -14.762 56.655  1.00 68.61  ? 228 GLN A CD  1 
ATOM   1282  O OE1 . GLN A 1 168 ? -73.600  -15.473 57.612  1.00 72.83  ? 228 GLN A OE1 1 
ATOM   1283  N NE2 . GLN A 1 168 ? -74.834  -15.098 55.789  1.00 81.36  ? 228 GLN A NE2 1 
ATOM   1284  N N   . VAL A 1 169 ? -71.997  -10.428 59.779  1.00 60.24  ? 229 VAL A N   1 
ATOM   1285  C CA  . VAL A 1 169 ? -72.001  -9.786  61.127  1.00 58.78  ? 229 VAL A CA  1 
ATOM   1286  C C   . VAL A 1 169 ? -70.801  -8.854  61.252  1.00 55.87  ? 229 VAL A C   1 
ATOM   1287  O O   . VAL A 1 169 ? -69.664  -9.319  61.169  1.00 55.04  ? 229 VAL A O   1 
ATOM   1288  C CB  . VAL A 1 169 ? -71.958  -10.815 62.268  1.00 65.83  ? 229 VAL A CB  1 
ATOM   1289  C CG1 . VAL A 1 169 ? -72.097  -10.119 63.616  1.00 63.55  ? 229 VAL A CG1 1 
ATOM   1290  C CG2 . VAL A 1 169 ? -72.997  -11.929 62.094  1.00 71.37  ? 229 VAL A CG2 1 
ATOM   1291  N N   . ILE A 1 170 ? -71.070  -7.571  61.438  1.00 56.44  ? 230 ILE A N   1 
ATOM   1292  C CA  . ILE A 1 170 ? -70.057  -6.558  61.840  1.00 56.79  ? 230 ILE A CA  1 
ATOM   1293  C C   . ILE A 1 170 ? -70.313  -6.267  63.311  1.00 56.69  ? 230 ILE A C   1 
ATOM   1294  O O   . ILE A 1 170 ? -71.472  -6.258  63.695  1.00 58.38  ? 230 ILE A O   1 
ATOM   1295  C CB  . ILE A 1 170 ? -70.125  -5.288  60.972  1.00 58.57  ? 230 ILE A CB  1 
ATOM   1296  C CG1 . ILE A 1 170 ? -69.598  -5.562  59.558  1.00 61.45  ? 230 ILE A CG1 1 
ATOM   1297  C CG2 . ILE A 1 170 ? -69.410  -4.123  61.649  1.00 57.45  ? 230 ILE A CG2 1 
ATOM   1298  C CD1 . ILE A 1 170 ? -69.953  -4.515  58.494  1.00 59.76  ? 230 ILE A CD1 1 
ATOM   1299  N N   . CYS A 1 171 ? -69.250  -6.103  64.090  1.00 63.43  ? 231 CYS A N   1 
ATOM   1300  C CA  . CYS A 1 171 ? -69.295  -5.620  65.484  1.00 61.39  ? 231 CYS A CA  1 
ATOM   1301  C C   . CYS A 1 171 ? -68.367  -4.414  65.608  1.00 53.00  ? 231 CYS A C   1 
ATOM   1302  O O   . CYS A 1 171 ? -67.168  -4.579  65.365  1.00 53.00  ? 231 CYS A O   1 
ATOM   1303  C CB  . CYS A 1 171 ? -68.943  -6.748  66.436  1.00 61.61  ? 231 CYS A CB  1 
ATOM   1304  S SG  . CYS A 1 171 ? -69.587  -6.385  68.083  1.00 75.96  ? 231 CYS A SG  1 
ATOM   1305  N N   . VAL A 1 172 ? -68.913  -3.244  65.917  1.00 47.41  ? 232 VAL A N   1 
ATOM   1306  C CA  . VAL A 1 172 ? -68.165  -1.957  65.783  1.00 49.48  ? 232 VAL A CA  1 
ATOM   1307  C C   . VAL A 1 172 ? -68.283  -1.153  67.063  1.00 44.39  ? 232 VAL A C   1 
ATOM   1308  O O   . VAL A 1 172 ? -69.387  -1.071  67.564  1.00 52.20  ? 232 VAL A O   1 
ATOM   1309  C CB  . VAL A 1 172 ? -68.715  -1.137  64.615  1.00 56.12  ? 232 VAL A CB  1 
ATOM   1310  C CG1 . VAL A 1 172 ? -70.201  -0.879  64.749  1.00 69.21  ? 232 VAL A CG1 1 
ATOM   1311  C CG2 . VAL A 1 172 ? -68.001  0.182   64.478  1.00 55.66  ? 232 VAL A CG2 1 
ATOM   1312  N N   . THR A 1 173 ? -67.193  -0.549  67.529  1.00 48.67  ? 233 THR A N   1 
ATOM   1313  C CA  . THR A 1 173 ? -67.142  0.381   68.706  1.00 47.13  ? 233 THR A CA  1 
ATOM   1314  C C   . THR A 1 173 ? -66.393  1.664   68.331  1.00 41.88  ? 233 THR A C   1 
ATOM   1315  O O   . THR A 1 173 ? -65.594  1.596   67.392  1.00 50.23  ? 233 THR A O   1 
ATOM   1316  C CB  . THR A 1 173 ? -66.471  -0.285  69.911  1.00 41.61  ? 233 THR A CB  1 
ATOM   1317  O OG1 . THR A 1 173 ? -66.267  0.725   70.886  1.00 41.52  ? 233 THR A OG1 1 
ATOM   1318  C CG2 . THR A 1 173 ? -65.116  -0.873  69.613  1.00 42.19  ? 233 THR A CG2 1 
ATOM   1319  N N   . ASP A 1 174 ? -66.644  2.790   68.988  1.00 37.64  ? 234 ASP A N   1 
ATOM   1320  C CA  . ASP A 1 174 ? -65.745  3.960   68.806  1.00 45.58  ? 234 ASP A CA  1 
ATOM   1321  C C   . ASP A 1 174 ? -64.932  4.127   70.081  1.00 45.57  ? 234 ASP A C   1 
ATOM   1322  O O   . ASP A 1 174 ? -64.146  5.091   70.164  1.00 54.92  ? 234 ASP A O   1 
ATOM   1323  C CB  . ASP A 1 174 ? -66.464  5.223   68.339  1.00 49.25  ? 234 ASP A CB  1 
ATOM   1324  C CG  . ASP A 1 174 ? -67.223  5.914   69.424  1.00 54.77  ? 234 ASP A CG  1 
ATOM   1325  O OD1 . ASP A 1 174 ? -67.432  5.251   70.451  1.00 68.34  ? 234 ASP A OD1 1 
ATOM   1326  O OD2 . ASP A 1 174 ? -67.599  7.101   69.213  1.00 63.01  ? 234 ASP A OD2 1 
ATOM   1327  N N   . GLY A 1 175 ? -65.103  3.179   71.001  1.00 46.43  ? 235 GLY A N   1 
ATOM   1328  C CA  . GLY A 1 175 ? -64.288  3.021   72.220  1.00 47.83  ? 235 GLY A CA  1 
ATOM   1329  C C   . GLY A 1 175 ? -64.675  3.967   73.338  1.00 46.18  ? 235 GLY A C   1 
ATOM   1330  O O   . GLY A 1 175 ? -63.956  3.972   74.352  1.00 57.29  ? 235 GLY A O   1 
ATOM   1331  N N   . GLU A 1 176 ? -65.748  4.749   73.183  1.00 56.22  ? 236 GLU A N   1 
ATOM   1332  C CA  . GLU A 1 176 ? -66.096  5.880   74.101  1.00 57.26  ? 236 GLU A CA  1 
ATOM   1333  C C   . GLU A 1 176 ? -66.527  5.369   75.479  1.00 59.75  ? 236 GLU A C   1 
ATOM   1334  O O   . GLU A 1 176 ? -66.244  6.111   76.450  1.00 65.95  ? 236 GLU A O   1 
ATOM   1335  C CB  . GLU A 1 176 ? -67.162  6.830   73.553  1.00 52.54  ? 236 GLU A CB  1 
ATOM   1336  C CG  . GLU A 1 176 ? -67.257  8.095   74.391  1.00 55.24  ? 236 GLU A CG  1 
ATOM   1337  C CD  . GLU A 1 176 ? -67.581  9.375   73.651  1.00 56.18  ? 236 GLU A CD  1 
ATOM   1338  O OE1 . GLU A 1 176 ? -68.124  9.278   72.532  1.00 59.51  ? 236 GLU A OE1 1 
ATOM   1339  O OE2 . GLU A 1 176 ? -67.237  10.453  74.186  1.00 48.24  ? 236 GLU A OE2 1 
ATOM   1340  N N   . ARG A 1 177 ? -67.179  4.199   75.577  1.00 48.90  ? 237 ARG A N   1 
ATOM   1341  C CA  . ARG A 1 177 ? -67.613  3.642   76.884  1.00 48.24  ? 237 ARG A CA  1 
ATOM   1342  C C   . ARG A 1 177 ? -67.349  2.145   76.925  1.00 44.71  ? 237 ARG A C   1 
ATOM   1343  O O   . ARG A 1 177 ? -68.299  1.402   76.917  1.00 50.10  ? 237 ARG A O   1 
ATOM   1344  C CB  . ARG A 1 177 ? -69.090  3.920   77.153  1.00 50.06  ? 237 ARG A CB  1 
ATOM   1345  C CG  . ARG A 1 177 ? -69.441  5.383   77.385  1.00 55.27  ? 237 ARG A CG  1 
ATOM   1346  C CD  . ARG A 1 177 ? -69.069  5.964   78.749  1.00 64.03  ? 237 ARG A CD  1 
ATOM   1347  N NE  . ARG A 1 177 ? -68.091  7.055   78.645  1.00 66.43  ? 237 ARG A NE  1 
ATOM   1348  C CZ  . ARG A 1 177 ? -68.395  8.350   78.509  1.00 66.01  ? 237 ARG A CZ  1 
ATOM   1349  N NH1 . ARG A 1 177 ? -69.654  8.762   78.458  1.00 69.83  ? 237 ARG A NH1 1 
ATOM   1350  N NH2 . ARG A 1 177 ? -67.419  9.235   78.423  1.00 65.30  ? 237 ARG A NH2 1 
ATOM   1351  N N   . ILE A 1 178 ? -66.097  1.724   77.000  1.00 51.36  ? 238 ILE A N   1 
ATOM   1352  C CA  . ILE A 1 178 ? -65.742  0.274   77.043  1.00 54.94  ? 238 ILE A CA  1 
ATOM   1353  C C   . ILE A 1 178 ? -66.107  -0.264  78.427  1.00 48.71  ? 238 ILE A C   1 
ATOM   1354  O O   . ILE A 1 178 ? -65.492  0.169   79.415  1.00 44.59  ? 238 ILE A O   1 
ATOM   1355  C CB  . ILE A 1 178 ? -64.245  0.063   76.735  1.00 60.38  ? 238 ILE A CB  1 
ATOM   1356  C CG1 . ILE A 1 178 ? -63.869  0.585   75.349  1.00 66.03  ? 238 ILE A CG1 1 
ATOM   1357  C CG2 . ILE A 1 178 ? -63.854  -1.390  76.939  1.00 57.18  ? 238 ILE A CG2 1 
ATOM   1358  C CD1 . ILE A 1 178 ? -64.623  -0.053  74.207  1.00 67.52  ? 238 ILE A CD1 1 
ATOM   1359  N N   . LEU A 1 179 ? -67.088  -1.166  78.493  1.00 48.20  ? 239 LEU A N   1 
ATOM   1360  C CA  . LEU A 1 179 ? -67.653  -1.712  79.759  1.00 47.33  ? 239 LEU A CA  1 
ATOM   1361  C C   . LEU A 1 179 ? -67.921  -0.526  80.708  1.00 46.37  ? 239 LEU A C   1 
ATOM   1362  O O   . LEU A 1 179 ? -68.357  0.527   80.210  1.00 49.97  ? 239 LEU A O   1 
ATOM   1363  C CB  . LEU A 1 179 ? -66.665  -2.742  80.323  1.00 47.29  ? 239 LEU A CB  1 
ATOM   1364  C CG  . LEU A 1 179 ? -66.408  -3.973  79.444  1.00 46.49  ? 239 LEU A CG  1 
ATOM   1365  C CD1 . LEU A 1 179 ? -65.070  -4.578  79.740  1.00 51.21  ? 239 LEU A CD1 1 
ATOM   1366  C CD2 . LEU A 1 179 ? -67.478  -5.028  79.614  1.00 51.08  ? 239 LEU A CD2 1 
ATOM   1367  N N   . GLY A 1 180 ? -67.657  -0.650  82.009  1.00 47.80  ? 240 GLY A N   1 
ATOM   1368  C CA  . GLY A 1 180 ? -67.735  0.479   82.947  1.00 46.64  ? 240 GLY A CA  1 
ATOM   1369  C C   . GLY A 1 180 ? -66.404  1.193   83.136  1.00 51.76  ? 240 GLY A C   1 
ATOM   1370  O O   . GLY A 1 180 ? -66.287  1.903   84.145  1.00 65.87  ? 240 GLY A O   1 
ATOM   1371  N N   . LEU A 1 181 ? -65.461  1.079   82.193  1.00 52.48  ? 241 LEU A N   1 
ATOM   1372  C CA  . LEU A 1 181 ? -64.088  1.655   82.314  1.00 49.05  ? 241 LEU A CA  1 
ATOM   1373  C C   . LEU A 1 181 ? -63.969  3.011   81.590  1.00 47.82  ? 241 LEU A C   1 
ATOM   1374  O O   . LEU A 1 181 ? -62.926  3.652   81.705  1.00 50.23  ? 241 LEU A O   1 
ATOM   1375  C CB  . LEU A 1 181 ? -63.105  0.633   81.749  1.00 50.87  ? 241 LEU A CB  1 
ATOM   1376  C CG  . LEU A 1 181 ? -63.216  -0.764  82.355  1.00 54.13  ? 241 LEU A CG  1 
ATOM   1377  C CD1 . LEU A 1 181 ? -62.369  -1.781  81.593  1.00 56.75  ? 241 LEU A CD1 1 
ATOM   1378  C CD2 . LEU A 1 181 ? -62.842  -0.730  83.831  1.00 57.92  ? 241 LEU A CD2 1 
ATOM   1379  N N   . GLY A 1 182 ? -65.014  3.450   80.901  1.00 52.18  ? 242 GLY A N   1 
ATOM   1380  C CA  . GLY A 1 182 ? -65.032  4.721   80.161  1.00 64.45  ? 242 GLY A CA  1 
ATOM   1381  C C   . GLY A 1 182 ? -64.261  4.651   78.848  1.00 65.42  ? 242 GLY A C   1 
ATOM   1382  O O   . GLY A 1 182 ? -64.296  3.570   78.183  1.00 51.50  ? 242 GLY A O   1 
ATOM   1383  N N   . ASP A 1 183 ? -63.619  5.775   78.484  1.00 63.81  ? 243 ASP A N   1 
ATOM   1384  C CA  . ASP A 1 183 ? -63.015  6.080   77.157  1.00 58.52  ? 243 ASP A CA  1 
ATOM   1385  C C   . ASP A 1 183 ? -61.630  5.422   77.027  1.00 53.50  ? 243 ASP A C   1 
ATOM   1386  O O   . ASP A 1 183 ? -60.678  5.869   77.687  1.00 51.54  ? 243 ASP A O   1 
ATOM   1387  C CB  . ASP A 1 183 ? -62.935  7.598   76.993  1.00 55.58  ? 243 ASP A CB  1 
ATOM   1388  C CG  . ASP A 1 183 ? -62.610  8.063   75.595  1.00 60.56  ? 243 ASP A CG  1 
ATOM   1389  O OD1 . ASP A 1 183 ? -62.104  7.228   74.803  1.00 62.08  ? 243 ASP A OD1 1 
ATOM   1390  O OD2 . ASP A 1 183 ? -62.877  9.260   75.312  1.00 59.45  ? 243 ASP A OD2 1 
ATOM   1391  N N   . LEU A 1 184 ? -61.513  4.375   76.215  1.00 46.86  ? 244 LEU A N   1 
ATOM   1392  C CA  . LEU A 1 184 ? -60.224  3.694   75.951  1.00 53.20  ? 244 LEU A CA  1 
ATOM   1393  C C   . LEU A 1 184 ? -59.856  3.928   74.476  1.00 53.86  ? 244 LEU A C   1 
ATOM   1394  O O   . LEU A 1 184 ? -58.978  3.216   73.918  1.00 46.63  ? 244 LEU A O   1 
ATOM   1395  C CB  . LEU A 1 184 ? -60.366  2.209   76.303  1.00 57.90  ? 244 LEU A CB  1 
ATOM   1396  C CG  . LEU A 1 184 ? -60.586  1.900   77.783  1.00 52.06  ? 244 LEU A CG  1 
ATOM   1397  C CD1 . LEU A 1 184 ? -60.535  0.393   78.030  1.00 50.66  ? 244 LEU A CD1 1 
ATOM   1398  C CD2 . LEU A 1 184 ? -59.563  2.614   78.657  1.00 49.81  ? 244 LEU A CD2 1 
ATOM   1399  N N   . GLY A 1 185 ? -60.469  4.941   73.871  1.00 60.32  ? 245 GLY A N   1 
ATOM   1400  C CA  . GLY A 1 185 ? -60.218  5.304   72.470  1.00 60.96  ? 245 GLY A CA  1 
ATOM   1401  C C   . GLY A 1 185 ? -60.023  4.061   71.628  1.00 63.53  ? 245 GLY A C   1 
ATOM   1402  O O   . GLY A 1 185 ? -60.785  3.067   71.804  1.00 61.48  ? 245 GLY A O   1 
ATOM   1403  N N   . CYS A 1 186 ? -58.984  4.087   70.799  1.00 58.10  ? 246 CYS A N   1 
ATOM   1404  C CA  . CYS A 1 186 ? -58.718  3.084   69.748  1.00 58.72  ? 246 CYS A CA  1 
ATOM   1405  C C   . CYS A 1 186 ? -58.465  1.696   70.368  1.00 61.86  ? 246 CYS A C   1 
ATOM   1406  O O   . CYS A 1 186 ? -58.565  0.682   69.621  1.00 61.02  ? 246 CYS A O   1 
ATOM   1407  C CB  . CYS A 1 186 ? -57.544  3.551   68.901  1.00 58.56  ? 246 CYS A CB  1 
ATOM   1408  S SG  . CYS A 1 186 ? -57.514  2.821   67.241  1.00 63.89  ? 246 CYS A SG  1 
ATOM   1409  N N   . GLN A 1 187 ? -58.191  1.627   71.679  1.00 52.07  ? 247 GLN A N   1 
ATOM   1410  C CA  . GLN A 1 187 ? -57.878  0.346   72.358  1.00 51.99  ? 247 GLN A CA  1 
ATOM   1411  C C   . GLN A 1 187 ? -59.183  -0.397  72.692  1.00 53.54  ? 247 GLN A C   1 
ATOM   1412  O O   . GLN A 1 187 ? -59.105  -1.519  73.245  1.00 45.84  ? 247 GLN A O   1 
ATOM   1413  C CB  . GLN A 1 187 ? -56.963  0.602   73.561  1.00 53.32  ? 247 GLN A CB  1 
ATOM   1414  C CG  . GLN A 1 187 ? -55.570  1.106   73.159  1.00 52.99  ? 247 GLN A CG  1 
ATOM   1415  C CD  . GLN A 1 187 ? -54.561  1.094   74.272  1.00 44.44  ? 247 GLN A CD  1 
ATOM   1416  O OE1 . GLN A 1 187 ? -54.824  0.617   75.357  1.00 54.76  ? 247 GLN A OE1 1 
ATOM   1417  N NE2 . GLN A 1 187 ? -53.397  1.634   74.018  1.00 46.94  ? 247 GLN A NE2 1 
ATOM   1418  N N   . GLY A 1 188 ? -60.337  0.167   72.312  1.00 56.42  ? 248 GLY A N   1 
ATOM   1419  C CA  . GLY A 1 188 ? -61.654  -0.490  72.426  1.00 53.05  ? 248 GLY A CA  1 
ATOM   1420  C C   . GLY A 1 188 ? -61.749  -1.797  71.636  1.00 47.78  ? 248 GLY A C   1 
ATOM   1421  O O   . GLY A 1 188 ? -62.665  -2.612  71.913  1.00 41.97  ? 248 GLY A O   1 
ATOM   1422  N N   . MET A 1 189 ? -60.840  -2.019  70.694  1.00 43.92  ? 249 MET A N   1 
ATOM   1423  C CA  . MET A 1 189 ? -60.934  -3.153  69.748  1.00 50.54  ? 249 MET A CA  1 
ATOM   1424  C C   . MET A 1 189 ? -61.094  -4.501  70.494  1.00 52.68  ? 249 MET A C   1 
ATOM   1425  O O   . MET A 1 189 ? -61.620  -5.453  69.900  1.00 54.79  ? 249 MET A O   1 
ATOM   1426  C CB  . MET A 1 189 ? -59.706  -3.177  68.832  1.00 50.14  ? 249 MET A CB  1 
ATOM   1427  C CG  . MET A 1 189 ? -59.672  -4.338  67.833  1.00 45.83  ? 249 MET A CG  1 
ATOM   1428  S SD  . MET A 1 189 ? -61.043  -4.261  66.669  1.00 48.19  ? 249 MET A SD  1 
ATOM   1429  C CE  . MET A 1 189 ? -60.250  -3.496  65.260  1.00 53.95  ? 249 MET A CE  1 
ATOM   1430  N N   . GLY A 1 190 ? -60.683  -4.612  71.750  1.00 55.94  ? 250 GLY A N   1 
ATOM   1431  C CA  . GLY A 1 190 ? -60.745  -5.897  72.472  1.00 61.08  ? 250 GLY A CA  1 
ATOM   1432  C C   . GLY A 1 190 ? -62.164  -6.447  72.511  1.00 60.97  ? 250 GLY A C   1 
ATOM   1433  O O   . GLY A 1 190 ? -62.336  -7.701  72.485  1.00 61.67  ? 250 GLY A O   1 
ATOM   1434  N N   . ILE A 1 191 ? -63.131  -5.531  72.568  1.00 57.72  ? 251 ILE A N   1 
ATOM   1435  C CA  . ILE A 1 191 ? -64.593  -5.796  72.738  1.00 60.77  ? 251 ILE A CA  1 
ATOM   1436  C C   . ILE A 1 191 ? -65.145  -6.414  71.451  1.00 56.11  ? 251 ILE A C   1 
ATOM   1437  O O   . ILE A 1 191 ? -65.573  -7.565  71.446  1.00 57.38  ? 251 ILE A O   1 
ATOM   1438  C CB  . ILE A 1 191 ? -65.324  -4.492  73.165  1.00 59.52  ? 251 ILE A CB  1 
ATOM   1439  C CG1 . ILE A 1 191 ? -64.878  -4.012  74.548  1.00 60.76  ? 251 ILE A CG1 1 
ATOM   1440  C CG2 . ILE A 1 191 ? -66.831  -4.659  73.104  1.00 61.09  ? 251 ILE A CG2 1 
ATOM   1441  C CD1 . ILE A 1 191 ? -65.002  -5.062  75.653  1.00 60.65  ? 251 ILE A CD1 1 
ATOM   1442  N N   . PRO A 1 192 ? -65.159  -5.681  70.313  1.00 52.55  ? 252 PRO A N   1 
ATOM   1443  C CA  . PRO A 1 192 ? -65.655  -6.249  69.073  1.00 51.95  ? 252 PRO A CA  1 
ATOM   1444  C C   . PRO A 1 192 ? -65.037  -7.622  68.805  1.00 54.77  ? 252 PRO A C   1 
ATOM   1445  O O   . PRO A 1 192 ? -65.757  -8.498  68.354  1.00 60.09  ? 252 PRO A O   1 
ATOM   1446  C CB  . PRO A 1 192 ? -65.235  -5.230  68.008  1.00 51.77  ? 252 PRO A CB  1 
ATOM   1447  C CG  . PRO A 1 192 ? -65.158  -3.922  68.743  1.00 50.84  ? 252 PRO A CG  1 
ATOM   1448  C CD  . PRO A 1 192 ? -64.736  -4.278  70.147  1.00 53.02  ? 252 PRO A CD  1 
ATOM   1449  N N   . VAL A 1 193 ? -63.737  -7.778  69.071  1.00 49.79  ? 253 VAL A N   1 
ATOM   1450  C CA  . VAL A 1 193 ? -63.028  -9.049  68.759  1.00 51.62  ? 253 VAL A CA  1 
ATOM   1451  C C   . VAL A 1 193 ? -63.597  -10.127 69.692  1.00 48.43  ? 253 VAL A C   1 
ATOM   1452  O O   . VAL A 1 193 ? -63.809  -11.286 69.254  1.00 45.63  ? 253 VAL A O   1 
ATOM   1453  C CB  . VAL A 1 193 ? -61.496  -8.921  68.846  1.00 45.82  ? 253 VAL A CB  1 
ATOM   1454  C CG1 . VAL A 1 193 ? -60.836  -10.299 68.707  1.00 46.41  ? 253 VAL A CG1 1 
ATOM   1455  C CG2 . VAL A 1 193 ? -60.943  -7.910  67.823  1.00 39.40  ? 253 VAL A CG2 1 
ATOM   1456  N N   . GLY A 1 194 ? -63.886  -9.732  70.921  1.00 46.08  ? 254 GLY A N   1 
ATOM   1457  C CA  . GLY A 1 194 ? -64.444  -10.644 71.926  1.00 47.66  ? 254 GLY A CA  1 
ATOM   1458  C C   . GLY A 1 194 ? -65.830  -11.089 71.534  1.00 45.41  ? 254 GLY A C   1 
ATOM   1459  O O   . GLY A 1 194 ? -66.065  -12.318 71.461  1.00 47.89  ? 254 GLY A O   1 
ATOM   1460  N N   . LYS A 1 195 ? -66.713  -10.119 71.298  1.00 47.29  ? 255 LYS A N   1 
ATOM   1461  C CA  . LYS A 1 195 ? -68.126  -10.369 70.944  1.00 46.91  ? 255 LYS A CA  1 
ATOM   1462  C C   . LYS A 1 195 ? -68.156  -11.405 69.821  1.00 48.58  ? 255 LYS A C   1 
ATOM   1463  O O   . LYS A 1 195 ? -68.819  -12.441 69.956  1.00 47.90  ? 255 LYS A O   1 
ATOM   1464  C CB  . LYS A 1 195 ? -68.806  -9.075  70.495  1.00 47.11  ? 255 LYS A CB  1 
ATOM   1465  C CG  . LYS A 1 195 ? -68.946  -7.996  71.564  1.00 51.97  ? 255 LYS A CG  1 
ATOM   1466  C CD  . LYS A 1 195 ? -70.044  -8.227  72.588  1.00 53.94  ? 255 LYS A CD  1 
ATOM   1467  C CE  . LYS A 1 195 ? -69.849  -7.326  73.795  1.00 59.43  ? 255 LYS A CE  1 
ATOM   1468  N NZ  . LYS A 1 195 ? -70.956  -7.440  74.769  1.00 62.92  ? 255 LYS A NZ  1 
ATOM   1469  N N   . LEU A 1 196 ? -67.403  -11.132 68.763  1.00 56.13  ? 256 LEU A N   1 
ATOM   1470  C CA  . LEU A 1 196 ? -67.477  -11.898 67.497  1.00 56.32  ? 256 LEU A CA  1 
ATOM   1471  C C   . LEU A 1 196 ? -66.938  -13.319 67.711  1.00 48.48  ? 256 LEU A C   1 
ATOM   1472  O O   . LEU A 1 196 ? -67.491  -14.233 67.116  1.00 57.56  ? 256 LEU A O   1 
ATOM   1473  C CB  . LEU A 1 196 ? -66.753  -11.105 66.405  1.00 52.36  ? 256 LEU A CB  1 
ATOM   1474  C CG  . LEU A 1 196 ? -67.507  -9.861  65.921  1.00 55.04  ? 256 LEU A CG  1 
ATOM   1475  C CD1 . LEU A 1 196 ? -66.740  -9.133  64.833  1.00 61.32  ? 256 LEU A CD1 1 
ATOM   1476  C CD2 . LEU A 1 196 ? -68.884  -10.217 65.400  1.00 57.42  ? 256 LEU A CD2 1 
ATOM   1477  N N   . ALA A 1 197 ? -65.945  -13.512 68.562  1.00 47.70  ? 257 ALA A N   1 
ATOM   1478  C CA  . ALA A 1 197 ? -65.465  -14.861 68.934  1.00 55.33  ? 257 ALA A CA  1 
ATOM   1479  C C   . ALA A 1 197 ? -66.648  -15.618 69.559  1.00 62.37  ? 257 ALA A C   1 
ATOM   1480  O O   . ALA A 1 197 ? -66.793  -16.846 69.326  1.00 61.33  ? 257 ALA A O   1 
ATOM   1481  C CB  . ALA A 1 197 ? -64.295  -14.770 69.892  1.00 55.27  ? 257 ALA A CB  1 
ATOM   1482  N N   . LEU A 1 198 ? -67.465  -14.908 70.341  1.00 63.60  ? 258 LEU A N   1 
ATOM   1483  C CA  . LEU A 1 198 ? -68.621  -15.505 71.073  1.00 66.04  ? 258 LEU A CA  1 
ATOM   1484  C C   . LEU A 1 198 ? -69.721  -15.806 70.059  1.00 54.16  ? 258 LEU A C   1 
ATOM   1485  O O   . LEU A 1 198 ? -70.316  -16.877 70.130  1.00 57.68  ? 258 LEU A O   1 
ATOM   1486  C CB  . LEU A 1 198 ? -69.103  -14.558 72.187  1.00 70.11  ? 258 LEU A CB  1 
ATOM   1487  C CG  . LEU A 1 198 ? -68.532  -14.841 73.582  1.00 70.78  ? 258 LEU A CG  1 
ATOM   1488  C CD1 . LEU A 1 198 ? -67.013  -14.849 73.584  1.00 80.75  ? 258 LEU A CD1 1 
ATOM   1489  C CD2 . LEU A 1 198 ? -69.025  -13.821 74.580  1.00 70.45  ? 258 LEU A CD2 1 
ATOM   1490  N N   . TYR A 1 199 ? -69.947  -14.890 69.128  1.00 55.27  ? 259 TYR A N   1 
ATOM   1491  C CA  . TYR A 1 199 ? -70.873  -15.104 67.996  1.00 55.48  ? 259 TYR A CA  1 
ATOM   1492  C C   . TYR A 1 199 ? -70.612  -16.487 67.400  1.00 50.42  ? 259 TYR A C   1 
ATOM   1493  O O   . TYR A 1 199 ? -71.562  -17.082 66.922  1.00 50.44  ? 259 TYR A O   1 
ATOM   1494  C CB  . TYR A 1 199 ? -70.693  -14.039 66.906  1.00 54.87  ? 259 TYR A CB  1 
ATOM   1495  C CG  . TYR A 1 199 ? -71.756  -12.982 66.903  1.00 57.74  ? 259 TYR A CG  1 
ATOM   1496  C CD1 . TYR A 1 199 ? -73.018  -13.250 66.406  1.00 55.38  ? 259 TYR A CD1 1 
ATOM   1497  C CD2 . TYR A 1 199 ? -71.507  -11.718 67.421  1.00 64.87  ? 259 TYR A CD2 1 
ATOM   1498  C CE1 . TYR A 1 199 ? -74.009  -12.278 66.421  1.00 61.41  ? 259 TYR A CE1 1 
ATOM   1499  C CE2 . TYR A 1 199 ? -72.479  -10.727 67.425  1.00 65.05  ? 259 TYR A CE2 1 
ATOM   1500  C CZ  . TYR A 1 199 ? -73.734  -11.014 66.923  1.00 65.33  ? 259 TYR A CZ  1 
ATOM   1501  O OH  . TYR A 1 199 ? -74.669  -10.026 66.939  1.00 83.30  ? 259 TYR A OH  1 
ATOM   1502  N N   . THR A 1 200 ? -69.355  -16.924 67.353  1.00 45.36  ? 260 THR A N   1 
ATOM   1503  C CA  . THR A 1 200 ? -68.946  -18.204 66.720  1.00 49.15  ? 260 THR A CA  1 
ATOM   1504  C C   . THR A 1 200 ? -69.075  -19.349 67.740  1.00 54.64  ? 260 THR A C   1 
ATOM   1505  O O   . THR A 1 200 ? -69.673  -20.420 67.395  1.00 52.53  ? 260 THR A O   1 
ATOM   1506  C CB  . THR A 1 200 ? -67.521  -18.140 66.149  1.00 46.84  ? 260 THR A CB  1 
ATOM   1507  O OG1 . THR A 1 200 ? -67.427  -17.075 65.192  1.00 42.59  ? 260 THR A OG1 1 
ATOM   1508  C CG2 . THR A 1 200 ? -67.083  -19.466 65.543  1.00 41.11  ? 260 THR A CG2 1 
ATOM   1509  N N   . ALA A 1 201 ? -68.503  -19.151 68.930  1.00 48.81  ? 261 ALA A N   1 
ATOM   1510  C CA  . ALA A 1 201 ? -68.412  -20.186 69.977  1.00 47.43  ? 261 ALA A CA  1 
ATOM   1511  C C   . ALA A 1 201 ? -69.816  -20.482 70.525  1.00 56.10  ? 261 ALA A C   1 
ATOM   1512  O O   . ALA A 1 201 ? -70.165  -21.684 70.638  1.00 56.59  ? 261 ALA A O   1 
ATOM   1513  C CB  . ALA A 1 201 ? -67.458  -19.721 71.048  1.00 46.22  ? 261 ALA A CB  1 
ATOM   1514  N N   . LEU A 1 202 ? -70.593  -19.430 70.829  1.00 65.86  ? 262 LEU A N   1 
ATOM   1515  C CA  . LEU A 1 202 ? -71.928  -19.504 71.499  1.00 61.43  ? 262 LEU A CA  1 
ATOM   1516  C C   . LEU A 1 202 ? -73.053  -19.624 70.469  1.00 59.04  ? 262 LEU A C   1 
ATOM   1517  O O   . LEU A 1 202 ? -73.999  -20.369 70.737  1.00 59.46  ? 262 LEU A O   1 
ATOM   1518  C CB  . LEU A 1 202 ? -72.172  -18.253 72.357  1.00 63.45  ? 262 LEU A CB  1 
ATOM   1519  C CG  . LEU A 1 202 ? -71.058  -17.863 73.339  1.00 63.50  ? 262 LEU A CG  1 
ATOM   1520  C CD1 . LEU A 1 202 ? -71.504  -16.681 74.196  1.00 58.30  ? 262 LEU A CD1 1 
ATOM   1521  C CD2 . LEU A 1 202 ? -70.611  -19.036 74.224  1.00 52.49  ? 262 LEU A CD2 1 
ATOM   1522  N N   . GLY A 1 203 ? -72.968  -18.893 69.354  1.00 64.92  ? 263 GLY A N   1 
ATOM   1523  C CA  . GLY A 1 203 ? -74.050  -18.769 68.349  1.00 74.76  ? 263 GLY A CA  1 
ATOM   1524  C C   . GLY A 1 203 ? -73.887  -19.703 67.141  1.00 75.89  ? 263 GLY A C   1 
ATOM   1525  O O   . GLY A 1 203 ? -74.930  -20.017 66.507  1.00 83.42  ? 263 GLY A O   1 
ATOM   1526  N N   . GLY A 1 204 ? -72.651  -20.072 66.764  1.00 56.10  ? 264 GLY A N   1 
ATOM   1527  C CA  . GLY A 1 204 ? -72.364  -20.930 65.605  1.00 48.62  ? 264 GLY A CA  1 
ATOM   1528  C C   . GLY A 1 204 ? -72.245  -20.174 64.294  1.00 44.88  ? 264 GLY A C   1 
ATOM   1529  O O   . GLY A 1 204 ? -72.200  -20.821 63.242  1.00 43.17  ? 264 GLY A O   1 
ATOM   1530  N N   . VAL A 1 205 ? -72.173  -18.848 64.327  1.00 46.16  ? 265 VAL A N   1 
ATOM   1531  C CA  . VAL A 1 205 ? -71.851  -18.013 63.130  1.00 50.60  ? 265 VAL A CA  1 
ATOM   1532  C C   . VAL A 1 205 ? -70.457  -18.427 62.640  1.00 50.09  ? 265 VAL A C   1 
ATOM   1533  O O   . VAL A 1 205 ? -69.593  -18.521 63.463  1.00 55.92  ? 265 VAL A O   1 
ATOM   1534  C CB  . VAL A 1 205 ? -71.906  -16.518 63.491  1.00 47.32  ? 265 VAL A CB  1 
ATOM   1535  C CG1 . VAL A 1 205 ? -71.709  -15.612 62.272  1.00 43.11  ? 265 VAL A CG1 1 
ATOM   1536  C CG2 . VAL A 1 205 ? -73.189  -16.188 64.237  1.00 44.71  ? 265 VAL A CG2 1 
ATOM   1537  N N   . ASP A 1 206 ? -70.237  -18.662 61.349  1.00 55.53  ? 266 ASP A N   1 
ATOM   1538  C CA  . ASP A 1 206 ? -68.878  -18.918 60.794  1.00 61.22  ? 266 ASP A CA  1 
ATOM   1539  C C   . ASP A 1 206 ? -67.953  -17.718 61.089  1.00 69.60  ? 266 ASP A C   1 
ATOM   1540  O O   . ASP A 1 206 ? -68.350  -16.539 61.006  1.00 57.02  ? 266 ASP A O   1 
ATOM   1541  C CB  . ASP A 1 206 ? -68.946  -19.234 59.296  1.00 61.71  ? 266 ASP A CB  1 
ATOM   1542  C CG  . ASP A 1 206 ? -67.621  -19.664 58.702  1.00 67.33  ? 266 ASP A CG  1 
ATOM   1543  O OD1 . ASP A 1 206 ? -66.969  -20.499 59.312  1.00 67.98  ? 266 ASP A OD1 1 
ATOM   1544  O OD2 . ASP A 1 206 ? -67.227  -19.095 57.669  1.00 96.10  ? 266 ASP A OD2 1 
ATOM   1545  N N   . PRO A 1 207 ? -66.679  -17.975 61.495  1.00 62.05  ? 267 PRO A N   1 
ATOM   1546  C CA  . PRO A 1 207 ? -65.768  -16.883 61.827  1.00 55.20  ? 267 PRO A CA  1 
ATOM   1547  C C   . PRO A 1 207 ? -65.561  -15.927 60.652  1.00 56.75  ? 267 PRO A C   1 
ATOM   1548  O O   . PRO A 1 207 ? -65.439  -14.729 60.854  1.00 51.87  ? 267 PRO A O   1 
ATOM   1549  C CB  . PRO A 1 207 ? -64.462  -17.601 62.181  1.00 54.57  ? 267 PRO A CB  1 
ATOM   1550  C CG  . PRO A 1 207 ? -64.875  -19.001 62.606  1.00 52.34  ? 267 PRO A CG  1 
ATOM   1551  C CD  . PRO A 1 207 ? -66.113  -19.307 61.797  1.00 54.14  ? 267 PRO A CD  1 
ATOM   1552  N N   . SER A 1 208 ? -65.529  -16.492 59.447  1.00 66.24  ? 268 SER A N   1 
ATOM   1553  C CA  . SER A 1 208 ? -65.038  -15.788 58.236  1.00 69.25  ? 268 SER A CA  1 
ATOM   1554  C C   . SER A 1 208 ? -66.028  -14.704 57.825  1.00 62.20  ? 268 SER A C   1 
ATOM   1555  O O   . SER A 1 208 ? -65.606  -13.791 57.112  1.00 57.72  ? 268 SER A O   1 
ATOM   1556  C CB  . SER A 1 208 ? -64.728  -16.735 57.109  1.00 68.18  ? 268 SER A CB  1 
ATOM   1557  O OG  . SER A 1 208 ? -65.460  -17.934 57.241  1.00 71.35  ? 268 SER A OG  1 
ATOM   1558  N N   . VAL A 1 209 ? -67.271  -14.773 58.302  1.00 63.11  ? 269 VAL A N   1 
ATOM   1559  C CA  . VAL A 1 209 ? -68.340  -13.797 57.922  1.00 60.53  ? 269 VAL A CA  1 
ATOM   1560  C C   . VAL A 1 209 ? -68.414  -12.677 58.965  1.00 54.21  ? 269 VAL A C   1 
ATOM   1561  O O   . VAL A 1 209 ? -69.241  -11.768 58.754  1.00 41.99  ? 269 VAL A O   1 
ATOM   1562  C CB  . VAL A 1 209 ? -69.702  -14.493 57.727  1.00 58.44  ? 269 VAL A CB  1 
ATOM   1563  C CG1 . VAL A 1 209 ? -69.617  -15.630 56.723  1.00 61.84  ? 269 VAL A CG1 1 
ATOM   1564  C CG2 . VAL A 1 209 ? -70.282  -15.014 59.021  1.00 61.05  ? 269 VAL A CG2 1 
ATOM   1565  N N   . CYS A 1 210 ? -67.561  -12.740 60.010  1.00 49.10  ? 270 CYS A N   1 
ATOM   1566  C CA  . CYS A 1 210 ? -67.553  -11.806 61.164  1.00 50.01  ? 270 CYS A CA  1 
ATOM   1567  C C   . CYS A 1 210 ? -66.421  -10.807 60.994  1.00 47.68  ? 270 CYS A C   1 
ATOM   1568  O O   . CYS A 1 210 ? -65.369  -11.246 60.598  1.00 46.30  ? 270 CYS A O   1 
ATOM   1569  C CB  . CYS A 1 210 ? -67.399  -12.560 62.472  1.00 48.82  ? 270 CYS A CB  1 
ATOM   1570  S SG  . CYS A 1 210 ? -68.713  -13.786 62.685  1.00 58.97  ? 270 CYS A SG  1 
ATOM   1571  N N   . LEU A 1 211 ? -66.667  -9.521  61.248  1.00 48.67  ? 271 LEU A N   1 
ATOM   1572  C CA  . LEU A 1 211 ? -65.699  -8.439  60.946  1.00 51.72  ? 271 LEU A CA  1 
ATOM   1573  C C   . LEU A 1 211 ? -65.640  -7.483  62.124  1.00 47.51  ? 271 LEU A C   1 
ATOM   1574  O O   . LEU A 1 211 ? -66.497  -6.635  62.276  1.00 54.03  ? 271 LEU A O   1 
ATOM   1575  C CB  . LEU A 1 211 ? -66.125  -7.716  59.661  1.00 59.56  ? 271 LEU A CB  1 
ATOM   1576  C CG  . LEU A 1 211 ? -65.435  -6.367  59.380  1.00 57.74  ? 271 LEU A CG  1 
ATOM   1577  C CD1 . LEU A 1 211 ? -63.938  -6.534  59.313  1.00 56.95  ? 271 LEU A CD1 1 
ATOM   1578  C CD2 . LEU A 1 211 ? -65.902  -5.718  58.074  1.00 52.44  ? 271 LEU A CD2 1 
ATOM   1579  N N   . PRO A 1 212 ? -64.612  -7.555  62.984  1.00 47.50  ? 272 PRO A N   1 
ATOM   1580  C CA  . PRO A 1 212 ? -64.489  -6.625  64.098  1.00 46.76  ? 272 PRO A CA  1 
ATOM   1581  C C   . PRO A 1 212 ? -63.983  -5.281  63.581  1.00 39.43  ? 272 PRO A C   1 
ATOM   1582  O O   . PRO A 1 212 ? -62.989  -5.273  62.981  1.00 41.20  ? 272 PRO A O   1 
ATOM   1583  C CB  . PRO A 1 212 ? -63.476  -7.288  65.052  1.00 45.78  ? 272 PRO A CB  1 
ATOM   1584  C CG  . PRO A 1 212 ? -63.006  -8.552  64.374  1.00 43.34  ? 272 PRO A CG  1 
ATOM   1585  C CD  . PRO A 1 212 ? -63.506  -8.515  62.945  1.00 46.83  ? 272 PRO A CD  1 
ATOM   1586  N N   . ILE A 1 213 ? -64.696  -4.199  63.847  1.00 42.91  ? 273 ILE A N   1 
ATOM   1587  C CA  . ILE A 1 213 ? -64.281  -2.831  63.425  1.00 48.92  ? 273 ILE A CA  1 
ATOM   1588  C C   . ILE A 1 213 ? -64.138  -1.920  64.644  1.00 47.32  ? 273 ILE A C   1 
ATOM   1589  O O   . ILE A 1 213 ? -64.928  -2.034  65.565  1.00 58.46  ? 273 ILE A O   1 
ATOM   1590  C CB  . ILE A 1 213 ? -65.282  -2.275  62.410  1.00 56.00  ? 273 ILE A CB  1 
ATOM   1591  C CG1 . ILE A 1 213 ? -65.363  -3.218  61.202  1.00 61.10  ? 273 ILE A CG1 1 
ATOM   1592  C CG2 . ILE A 1 213 ? -64.921  -0.833  62.035  1.00 55.52  ? 273 ILE A CG2 1 
ATOM   1593  C CD1 . ILE A 1 213 ? -66.329  -2.784  60.087  1.00 61.30  ? 273 ILE A CD1 1 
ATOM   1594  N N   . THR A 1 214 ? -63.174  -1.024  64.625  1.00 44.81  ? 274 THR A N   1 
ATOM   1595  C CA  . THR A 1 214 ? -63.081  0.096   65.587  1.00 43.82  ? 274 THR A CA  1 
ATOM   1596  C C   . THR A 1 214 ? -63.055  1.391   64.783  1.00 42.58  ? 274 THR A C   1 
ATOM   1597  O O   . THR A 1 214 ? -62.243  1.501   63.861  1.00 41.76  ? 274 THR A O   1 
ATOM   1598  C CB  . THR A 1 214 ? -61.835  -0.020  66.477  1.00 44.82  ? 274 THR A CB  1 
ATOM   1599  O OG1 . THR A 1 214 ? -61.889  -1.238  67.220  1.00 36.10  ? 274 THR A OG1 1 
ATOM   1600  C CG2 . THR A 1 214 ? -61.676  1.181   67.389  1.00 42.58  ? 274 THR A CG2 1 
ATOM   1601  N N   . ILE A 1 215 ? -63.862  2.358   65.156  1.00 46.57  ? 275 ILE A N   1 
ATOM   1602  C CA  . ILE A 1 215 ? -63.795  3.725   64.560  1.00 49.79  ? 275 ILE A CA  1 
ATOM   1603  C C   . ILE A 1 215 ? -62.956  4.588   65.497  1.00 46.49  ? 275 ILE A C   1 
ATOM   1604  O O   . ILE A 1 215 ? -63.454  4.892   66.559  1.00 46.17  ? 275 ILE A O   1 
ATOM   1605  C CB  . ILE A 1 215 ? -65.213  4.304   64.416  1.00 55.24  ? 275 ILE A CB  1 
ATOM   1606  C CG1 . ILE A 1 215 ? -66.186  3.375   63.676  1.00 55.36  ? 275 ILE A CG1 1 
ATOM   1607  C CG2 . ILE A 1 215 ? -65.158  5.715   63.854  1.00 55.29  ? 275 ILE A CG2 1 
ATOM   1608  C CD1 . ILE A 1 215 ? -65.992  3.294   62.192  1.00 63.33  ? 275 ILE A CD1 1 
ATOM   1609  N N   . ASP A 1 216 ? -61.725  4.950   65.138  1.00 50.94  ? 276 ASP A N   1 
ATOM   1610  C CA  . ASP A 1 216 ? -60.885  5.876   65.964  1.00 54.49  ? 276 ASP A CA  1 
ATOM   1611  C C   . ASP A 1 216 ? -61.174  7.335   65.572  1.00 52.50  ? 276 ASP A C   1 
ATOM   1612  O O   . ASP A 1 216 ? -60.887  7.719   64.399  1.00 50.70  ? 276 ASP A O   1 
ATOM   1613  C CB  . ASP A 1 216 ? -59.395  5.563   65.819  1.00 51.39  ? 276 ASP A CB  1 
ATOM   1614  C CG  . ASP A 1 216 ? -58.440  6.310   66.752  1.00 57.11  ? 276 ASP A CG  1 
ATOM   1615  O OD1 . ASP A 1 216 ? -58.882  6.856   67.807  1.00 58.03  ? 276 ASP A OD1 1 
ATOM   1616  O OD2 . ASP A 1 216 ? -57.226  6.307   66.443  1.00 66.89  ? 276 ASP A OD2 1 
ATOM   1617  N N   . VAL A 1 217 ? -61.714  8.118   66.499  1.00 50.37  ? 277 VAL A N   1 
ATOM   1618  C CA  . VAL A 1 217 ? -61.973  9.572   66.264  1.00 60.48  ? 277 VAL A CA  1 
ATOM   1619  C C   . VAL A 1 217 ? -61.177  10.398  67.276  1.00 57.30  ? 277 VAL A C   1 
ATOM   1620  O O   . VAL A 1 217 ? -61.388  11.606  67.366  1.00 58.99  ? 277 VAL A O   1 
ATOM   1621  C CB  . VAL A 1 217 ? -63.481  9.874   66.333  1.00 62.21  ? 277 VAL A CB  1 
ATOM   1622  C CG1 . VAL A 1 217 ? -64.234  9.170   65.207  1.00 64.99  ? 277 VAL A CG1 1 
ATOM   1623  C CG2 . VAL A 1 217 ? -64.081  9.489   67.665  1.00 63.93  ? 277 VAL A CG2 1 
ATOM   1624  N N   . GLY A 1 218 ? -60.263  9.751   67.984  1.00 68.15  ? 278 GLY A N   1 
ATOM   1625  C CA  . GLY A 1 218 ? -59.568  10.314  69.158  1.00 72.76  ? 278 GLY A CA  1 
ATOM   1626  C C   . GLY A 1 218 ? -60.069  9.705   70.453  1.00 61.64  ? 278 GLY A C   1 
ATOM   1627  O O   . GLY A 1 218 ? -60.890  8.781   70.398  1.00 69.61  ? 278 GLY A O   1 
ATOM   1628  N N   . THR A 1 219 ? -59.555  10.201  71.571  1.00 54.06  ? 279 THR A N   1 
ATOM   1629  C CA  . THR A 1 219 ? -59.918  9.759   72.934  1.00 60.54  ? 279 THR A CA  1 
ATOM   1630  C C   . THR A 1 219 ? -59.712  10.951  73.863  1.00 58.39  ? 279 THR A C   1 
ATOM   1631  O O   . THR A 1 219 ? -58.874  11.776  73.518  1.00 68.78  ? 279 THR A O   1 
ATOM   1632  C CB  . THR A 1 219 ? -59.123  8.508   73.338  1.00 62.25  ? 279 THR A CB  1 
ATOM   1633  O OG1 . THR A 1 219 ? -59.493  8.083   74.651  1.00 62.15  ? 279 THR A OG1 1 
ATOM   1634  C CG2 . THR A 1 219 ? -57.631  8.732   73.322  1.00 58.73  ? 279 THR A CG2 1 
ATOM   1635  N N   . ASN A 1 220 ? -60.457  11.030  74.966  1.00 49.79  ? 280 ASN A N   1 
ATOM   1636  C CA  . ASN A 1 220 ? -60.335  12.124  75.965  1.00 51.80  ? 280 ASN A CA  1 
ATOM   1637  C C   . ASN A 1 220 ? -59.522  11.656  77.174  1.00 55.81  ? 280 ASN A C   1 
ATOM   1638  O O   . ASN A 1 220 ? -59.054  12.537  77.945  1.00 63.73  ? 280 ASN A O   1 
ATOM   1639  C CB  . ASN A 1 220 ? -61.717  12.625  76.372  1.00 53.16  ? 280 ASN A CB  1 
ATOM   1640  C CG  . ASN A 1 220 ? -62.495  13.191  75.208  1.00 47.91  ? 280 ASN A CG  1 
ATOM   1641  O OD1 . ASN A 1 220 ? -61.935  13.810  74.313  1.00 44.87  ? 280 ASN A OD1 1 
ATOM   1642  N ND2 . ASN A 1 220 ? -63.793  12.989  75.228  1.00 48.73  ? 280 ASN A ND2 1 
ATOM   1643  N N   . ASN A 1 221 ? -59.371  10.331  77.325  1.00 61.84  ? 281 ASN A N   1 
ATOM   1644  C CA  . ASN A 1 221 ? -58.493  9.658   78.324  1.00 61.12  ? 281 ASN A CA  1 
ATOM   1645  C C   . ASN A 1 221 ? -57.078  10.276  78.261  1.00 64.80  ? 281 ASN A C   1 
ATOM   1646  O O   . ASN A 1 221 ? -56.292  9.920   77.340  1.00 78.49  ? 281 ASN A O   1 
ATOM   1647  C CB  . ASN A 1 221 ? -58.522  8.147   78.062  1.00 54.65  ? 281 ASN A CB  1 
ATOM   1648  C CG  . ASN A 1 221 ? -57.841  7.337   79.131  1.00 54.39  ? 281 ASN A CG  1 
ATOM   1649  O OD1 . ASN A 1 221 ? -56.986  7.852   79.822  1.00 66.60  ? 281 ASN A OD1 1 
ATOM   1650  N ND2 . ASN A 1 221 ? -58.205  6.077   79.273  1.00 54.94  ? 281 ASN A ND2 1 
ATOM   1651  N N   . GLU A 1 222 ? -56.768  11.176  79.196  1.00 61.88  ? 282 GLU A N   1 
ATOM   1652  C CA  . GLU A 1 222 ? -55.477  11.919  79.292  1.00 64.67  ? 282 GLU A CA  1 
ATOM   1653  C C   . GLU A 1 222 ? -54.293  10.962  79.495  1.00 56.77  ? 282 GLU A C   1 
ATOM   1654  O O   . GLU A 1 222 ? -53.211  11.258  78.969  1.00 46.05  ? 282 GLU A O   1 
ATOM   1655  C CB  . GLU A 1 222 ? -55.522  12.901  80.469  1.00 69.88  ? 282 GLU A CB  1 
ATOM   1656  C CG  . GLU A 1 222 ? -56.566  13.981  80.311  1.00 79.90  ? 282 GLU A CG  1 
ATOM   1657  C CD  . GLU A 1 222 ? -56.201  14.998  79.245  1.00 88.18  ? 282 GLU A CD  1 
ATOM   1658  O OE1 . GLU A 1 222 ? -55.111  14.838  78.648  1.00 88.55  ? 282 GLU A OE1 1 
ATOM   1659  O OE2 . GLU A 1 222 ? -57.012  15.916  79.001  1.00 91.12  ? 282 GLU A OE2 1 
ATOM   1660  N N   . LYS A 1 223 ? -54.496  9.878   80.261  1.00 54.12  ? 283 LYS A N   1 
ATOM   1661  C CA  . LYS A 1 223 ? -53.508  8.789   80.506  1.00 59.24  ? 283 LYS A CA  1 
ATOM   1662  C C   . LYS A 1 223 ? -53.068  8.193   79.149  1.00 61.77  ? 283 LYS A C   1 
ATOM   1663  O O   . LYS A 1 223 ? -51.863  7.948   78.953  1.00 69.24  ? 283 LYS A O   1 
ATOM   1664  C CB  . LYS A 1 223 ? -54.113  7.729   81.437  1.00 61.30  ? 283 LYS A CB  1 
ATOM   1665  C CG  . LYS A 1 223 ? -53.223  7.200   82.560  1.00 75.92  ? 283 LYS A CG  1 
ATOM   1666  C CD  . LYS A 1 223 ? -53.376  5.697   82.832  1.00 85.71  ? 283 LYS A CD  1 
ATOM   1667  C CE  . LYS A 1 223 ? -52.185  5.061   83.538  1.00 83.22  ? 283 LYS A CE  1 
ATOM   1668  N NZ  . LYS A 1 223 ? -52.564  3.768   84.144  1.00 77.75  ? 283 LYS A NZ  1 
ATOM   1669  N N   . LEU A 1 224 ? -53.998  7.986   78.223  1.00 57.55  ? 284 LEU A N   1 
ATOM   1670  C CA  . LEU A 1 224 ? -53.714  7.328   76.930  1.00 56.02  ? 284 LEU A CA  1 
ATOM   1671  C C   . LEU A 1 224 ? -53.121  8.317   75.934  1.00 53.94  ? 284 LEU A C   1 
ATOM   1672  O O   . LEU A 1 224 ? -52.311  7.873   75.112  1.00 55.09  ? 284 LEU A O   1 
ATOM   1673  C CB  . LEU A 1 224 ? -55.021  6.730   76.401  1.00 55.98  ? 284 LEU A CB  1 
ATOM   1674  C CG  . LEU A 1 224 ? -55.454  5.432   77.080  1.00 56.14  ? 284 LEU A CG  1 
ATOM   1675  C CD1 . LEU A 1 224 ? -56.616  4.833   76.319  1.00 62.91  ? 284 LEU A CD1 1 
ATOM   1676  C CD2 . LEU A 1 224 ? -54.296  4.418   77.145  1.00 53.78  ? 284 LEU A CD2 1 
ATOM   1677  N N   . LEU A 1 225 ? -53.526  9.591   75.970  1.00 57.58  ? 285 LEU A N   1 
ATOM   1678  C CA  . LEU A 1 225 ? -52.915  10.641  75.111  1.00 55.63  ? 285 LEU A CA  1 
ATOM   1679  C C   . LEU A 1 225 ? -51.418  10.746  75.410  1.00 61.32  ? 285 LEU A C   1 
ATOM   1680  O O   . LEU A 1 225 ? -50.661  10.941  74.458  1.00 62.36  ? 285 LEU A O   1 
ATOM   1681  C CB  . LEU A 1 225 ? -53.610  11.981  75.343  1.00 57.63  ? 285 LEU A CB  1 
ATOM   1682  C CG  . LEU A 1 225 ? -54.952  12.105  74.636  1.00 59.35  ? 285 LEU A CG  1 
ATOM   1683  C CD1 . LEU A 1 225 ? -55.621  13.429  74.953  1.00 67.34  ? 285 LEU A CD1 1 
ATOM   1684  C CD2 . LEU A 1 225 ? -54.782  11.941  73.142  1.00 59.06  ? 285 LEU A CD2 1 
ATOM   1685  N N   . ASN A 1 226 ? -51.014  10.579  76.673  1.00 62.11  ? 286 ASN A N   1 
ATOM   1686  C CA  . ASN A 1 226 ? -49.620  10.815  77.132  1.00 58.56  ? 286 ASN A CA  1 
ATOM   1687  C C   . ASN A 1 226 ? -48.879  9.491   77.226  1.00 56.61  ? 286 ASN A C   1 
ATOM   1688  O O   . ASN A 1 226 ? -47.688  9.553   77.434  1.00 65.82  ? 286 ASN A O   1 
ATOM   1689  C CB  . ASN A 1 226 ? -49.578  11.548  78.479  1.00 61.50  ? 286 ASN A CB  1 
ATOM   1690  C CG  . ASN A 1 226 ? -50.272  12.892  78.450  1.00 67.33  ? 286 ASN A CG  1 
ATOM   1691  O OD1 . ASN A 1 226 ? -50.269  13.579  77.423  1.00 61.97  ? 286 ASN A OD1 1 
ATOM   1692  N ND2 . ASN A 1 226 ? -50.947  13.225  79.541  1.00 81.94  ? 286 ASN A ND2 1 
ATOM   1693  N N   . ASP A 1 227 ? -49.563  8.351   77.106  1.00 64.17  ? 287 ASP A N   1 
ATOM   1694  C CA  . ASP A 1 227 ? -48.930  7.005   77.066  1.00 64.74  ? 287 ASP A CA  1 
ATOM   1695  C C   . ASP A 1 227 ? -48.323  6.828   75.674  1.00 61.36  ? 287 ASP A C   1 
ATOM   1696  O O   . ASP A 1 227 ? -49.038  7.081   74.702  1.00 67.12  ? 287 ASP A O   1 
ATOM   1697  C CB  . ASP A 1 227 ? -49.919  5.879   77.400  1.00 68.33  ? 287 ASP A CB  1 
ATOM   1698  C CG  . ASP A 1 227 ? -49.300  4.485   77.522  1.00 69.03  ? 287 ASP A CG  1 
ATOM   1699  O OD1 . ASP A 1 227 ? -48.062  4.317   77.264  1.00 63.98  ? 287 ASP A OD1 1 
ATOM   1700  O OD2 . ASP A 1 227 ? -50.067  3.558   77.841  1.00 84.84  ? 287 ASP A OD2 1 
ATOM   1701  N N   . GLU A 1 228 ? -47.048  6.438   75.596  1.00 68.48  ? 288 GLU A N   1 
ATOM   1702  C CA  . GLU A 1 228 ? -46.275  6.311   74.336  1.00 65.39  ? 288 GLU A CA  1 
ATOM   1703  C C   . GLU A 1 228 ? -46.631  4.999   73.620  1.00 63.17  ? 288 GLU A C   1 
ATOM   1704  O O   . GLU A 1 228 ? -46.172  4.872   72.498  1.00 66.08  ? 288 GLU A O   1 
ATOM   1705  C CB  . GLU A 1 228 ? -44.771  6.385   74.621  1.00 74.48  ? 288 GLU A CB  1 
ATOM   1706  C CG  . GLU A 1 228 ? -44.218  5.127   75.299  1.00 79.35  ? 288 GLU A CG  1 
ATOM   1707  C CD  . GLU A 1 228 ? -42.745  5.107   75.671  1.00 80.84  ? 288 GLU A CD  1 
ATOM   1708  O OE1 . GLU A 1 228 ? -41.991  6.050   75.288  1.00 78.06  ? 288 GLU A OE1 1 
ATOM   1709  O OE2 . GLU A 1 228 ? -42.359  4.139   76.348  1.00 73.20  ? 288 GLU A OE2 1 
ATOM   1710  N N   . PHE A 1 229 ? -47.393  4.066   74.217  1.00 63.09  ? 289 PHE A N   1 
ATOM   1711  C CA  . PHE A 1 229 ? -47.837  2.813   73.535  1.00 71.60  ? 289 PHE A CA  1 
ATOM   1712  C C   . PHE A 1 229 ? -49.293  2.868   73.039  1.00 65.07  ? 289 PHE A C   1 
ATOM   1713  O O   . PHE A 1 229 ? -49.767  1.840   72.463  1.00 53.04  ? 289 PHE A O   1 
ATOM   1714  C CB  . PHE A 1 229 ? -47.635  1.589   74.424  1.00 65.09  ? 289 PHE A CB  1 
ATOM   1715  C CG  . PHE A 1 229 ? -46.178  1.320   74.663  1.00 66.63  ? 289 PHE A CG  1 
ATOM   1716  C CD1 . PHE A 1 229 ? -45.264  1.397   73.620  1.00 62.76  ? 289 PHE A CD1 1 
ATOM   1717  C CD2 . PHE A 1 229 ? -45.723  0.990   75.931  1.00 63.08  ? 289 PHE A CD2 1 
ATOM   1718  C CE1 . PHE A 1 229 ? -43.919  1.163   73.850  1.00 65.51  ? 289 PHE A CE1 1 
ATOM   1719  C CE2 . PHE A 1 229 ? -44.378  0.743   76.155  1.00 58.89  ? 289 PHE A CE2 1 
ATOM   1720  C CZ  . PHE A 1 229 ? -43.479  0.835   75.116  1.00 61.84  ? 289 PHE A CZ  1 
ATOM   1721  N N   . TYR A 1 230 ? -49.961  4.012   73.187  1.00 51.30  ? 290 TYR A N   1 
ATOM   1722  C CA  . TYR A 1 230 ? -51.343  4.160   72.698  1.00 56.42  ? 290 TYR A CA  1 
ATOM   1723  C C   . TYR A 1 230 ? -51.254  4.021   71.186  1.00 59.59  ? 290 TYR A C   1 
ATOM   1724  O O   . TYR A 1 230 ? -50.373  4.661   70.589  1.00 66.65  ? 290 TYR A O   1 
ATOM   1725  C CB  . TYR A 1 230 ? -52.015  5.445   73.196  1.00 57.51  ? 290 TYR A CB  1 
ATOM   1726  C CG  . TYR A 1 230 ? -53.405  5.705   72.653  1.00 53.66  ? 290 TYR A CG  1 
ATOM   1727  C CD1 . TYR A 1 230 ? -54.467  4.832   72.863  1.00 50.53  ? 290 TYR A CD1 1 
ATOM   1728  C CD2 . TYR A 1 230 ? -53.647  6.839   71.902  1.00 53.19  ? 290 TYR A CD2 1 
ATOM   1729  C CE1 . TYR A 1 230 ? -55.722  5.093   72.336  1.00 54.72  ? 290 TYR A CE1 1 
ATOM   1730  C CE2 . TYR A 1 230 ? -54.894  7.110   71.375  1.00 54.92  ? 290 TYR A CE2 1 
ATOM   1731  C CZ  . TYR A 1 230 ? -55.945  6.245   71.591  1.00 57.97  ? 290 TYR A CZ  1 
ATOM   1732  O OH  . TYR A 1 230 ? -57.148  6.584   71.012  1.00 64.90  ? 290 TYR A OH  1 
ATOM   1733  N N   . ILE A 1 231 ? -52.148  3.191   70.636  1.00 56.12  ? 291 ILE A N   1 
ATOM   1734  C CA  . ILE A 1 231 ? -52.187  2.761   69.216  1.00 52.33  ? 291 ILE A CA  1 
ATOM   1735  C C   . ILE A 1 231 ? -53.120  3.674   68.419  1.00 47.08  ? 291 ILE A C   1 
ATOM   1736  O O   . ILE A 1 231 ? -53.295  3.442   67.233  1.00 53.16  ? 291 ILE A O   1 
ATOM   1737  C CB  . ILE A 1 231 ? -52.638  1.289   69.108  1.00 48.74  ? 291 ILE A CB  1 
ATOM   1738  C CG1 . ILE A 1 231 ? -54.116  1.115   69.450  1.00 51.18  ? 291 ILE A CG1 1 
ATOM   1739  C CG2 . ILE A 1 231 ? -51.758  0.386   69.949  1.00 45.63  ? 291 ILE A CG2 1 
ATOM   1740  C CD1 . ILE A 1 231 ? -54.574  -0.316  69.449  1.00 60.33  ? 291 ILE A CD1 1 
ATOM   1741  N N   . GLY A 1 232 ? -53.763  4.647   69.030  1.00 52.62  ? 292 GLY A N   1 
ATOM   1742  C CA  . GLY A 1 232 ? -54.721  5.527   68.316  1.00 50.59  ? 292 GLY A CA  1 
ATOM   1743  C C   . GLY A 1 232 ? -54.144  6.886   67.987  1.00 46.22  ? 292 GLY A C   1 
ATOM   1744  O O   . GLY A 1 232 ? -52.970  7.131   68.321  1.00 48.64  ? 292 GLY A O   1 
ATOM   1745  N N   . LEU A 1 233 ? -54.972  7.752   67.407  1.00 48.92  ? 293 LEU A N   1 
ATOM   1746  C CA  . LEU A 1 233 ? -54.665  9.182   67.144  1.00 49.13  ? 293 LEU A CA  1 
ATOM   1747  C C   . LEU A 1 233 ? -54.429  9.883   68.471  1.00 49.97  ? 293 LEU A C   1 
ATOM   1748  O O   . LEU A 1 233 ? -55.339  9.814   69.276  1.00 51.84  ? 293 LEU A O   1 
ATOM   1749  C CB  . LEU A 1 233 ? -55.840  9.815   66.390  1.00 44.46  ? 293 LEU A CB  1 
ATOM   1750  C CG  . LEU A 1 233 ? -56.267  9.096   65.096  1.00 48.36  ? 293 LEU A CG  1 
ATOM   1751  C CD1 . LEU A 1 233 ? -57.167  9.975   64.243  1.00 48.19  ? 293 LEU A CD1 1 
ATOM   1752  C CD2 . LEU A 1 233 ? -55.099  8.614   64.222  1.00 45.55  ? 293 LEU A CD2 1 
ATOM   1753  N N   . ARG A 1 234 ? -53.267  10.517  68.675  1.00 51.62  ? 294 ARG A N   1 
ATOM   1754  C CA  . ARG A 1 234 ? -53.007  11.415  69.846  1.00 55.78  ? 294 ARG A CA  1 
ATOM   1755  C C   . ARG A 1 234 ? -53.762  12.746  69.665  1.00 51.67  ? 294 ARG A C   1 
ATOM   1756  O O   . ARG A 1 234 ? -53.088  13.795  69.464  1.00 41.10  ? 294 ARG A O   1 
ATOM   1757  C CB  . ARG A 1 234 ? -51.524  11.773  70.036  1.00 57.75  ? 294 ARG A CB  1 
ATOM   1758  C CG  . ARG A 1 234 ? -50.689  10.664  70.648  1.00 58.00  ? 294 ARG A CG  1 
ATOM   1759  C CD  . ARG A 1 234 ? -49.464  11.008  71.508  1.00 50.80  ? 294 ARG A CD  1 
ATOM   1760  N NE  . ARG A 1 234 ? -49.262  9.784   72.274  1.00 49.76  ? 294 ARG A NE  1 
ATOM   1761  C CZ  . ARG A 1 234 ? -48.852  8.639   71.756  1.00 51.62  ? 294 ARG A CZ  1 
ATOM   1762  N NH1 . ARG A 1 234 ? -48.492  8.590   70.484  1.00 59.51  ? 294 ARG A NH1 1 
ATOM   1763  N NH2 . ARG A 1 234 ? -48.765  7.553   72.496  1.00 57.64  ? 294 ARG A NH2 1 
ATOM   1764  N N   . GLN A 1 235 ? -55.094  12.703  69.752  1.00 46.45  ? 295 GLN A N   1 
ATOM   1765  C CA  . GLN A 1 235 ? -55.965  13.895  69.772  1.00 58.10  ? 295 GLN A CA  1 
ATOM   1766  C C   . GLN A 1 235 ? -57.235  13.587  70.566  1.00 63.88  ? 295 GLN A C   1 
ATOM   1767  O O   . GLN A 1 235 ? -57.567  12.381  70.691  1.00 60.04  ? 295 GLN A O   1 
ATOM   1768  C CB  . GLN A 1 235 ? -56.309  14.313  68.347  1.00 67.56  ? 295 GLN A CB  1 
ATOM   1769  C CG  . GLN A 1 235 ? -56.937  13.213  67.509  1.00 65.46  ? 295 GLN A CG  1 
ATOM   1770  C CD  . GLN A 1 235 ? -57.674  13.779  66.307  1.00 60.40  ? 295 GLN A CD  1 
ATOM   1771  O OE1 . GLN A 1 235 ? -57.182  13.732  65.190  1.00 60.90  ? 295 GLN A OE1 1 
ATOM   1772  N NE2 . GLN A 1 235 ? -58.868  14.323  66.516  1.00 55.50  ? 295 GLN A NE2 1 
ATOM   1773  N N   . LYS A 1 236 ? -57.906  14.623  71.088  1.00 67.53  ? 296 LYS A N   1 
ATOM   1774  C CA  . LYS A 1 236 ? -59.161  14.437  71.856  1.00 76.83  ? 296 LYS A CA  1 
ATOM   1775  C C   . LYS A 1 236 ? -60.274  14.144  70.827  1.00 75.78  ? 296 LYS A C   1 
ATOM   1776  O O   . LYS A 1 236 ? -60.067  14.417  69.641  1.00 70.80  ? 296 LYS A O   1 
ATOM   1777  C CB  . LYS A 1 236 ? -59.354  15.593  72.845  1.00 90.28  ? 296 LYS A CB  1 
ATOM   1778  C CG  . LYS A 1 236 ? -60.392  16.650  72.482  1.00 114.78 ? 296 LYS A CG  1 
ATOM   1779  C CD  . LYS A 1 236 ? -60.052  18.035  72.947  1.00 116.80 ? 296 LYS A CD  1 
ATOM   1780  C CE  . LYS A 1 236 ? -61.223  18.984  72.774  1.00 104.39 ? 296 LYS A CE  1 
ATOM   1781  N NZ  . LYS A 1 236 ? -60.831  20.388  73.035  1.00 105.59 ? 296 LYS A NZ  1 
ATOM   1782  N N   . ARG A 1 237 ? -61.382  13.533  71.247  1.00 69.25  ? 297 ARG A N   1 
ATOM   1783  C CA  . ARG A 1 237 ? -62.447  13.056  70.324  1.00 67.56  ? 297 ARG A CA  1 
ATOM   1784  C C   . ARG A 1 237 ? -62.990  14.213  69.490  1.00 62.14  ? 297 ARG A C   1 
ATOM   1785  O O   . ARG A 1 237 ? -63.295  15.261  70.069  1.00 61.52  ? 297 ARG A O   1 
ATOM   1786  C CB  . ARG A 1 237 ? -63.607  12.406  71.084  1.00 67.28  ? 297 ARG A CB  1 
ATOM   1787  C CG  . ARG A 1 237 ? -63.334  10.974  71.502  1.00 64.52  ? 297 ARG A CG  1 
ATOM   1788  C CD  . ARG A 1 237 ? -64.543  10.274  72.048  1.00 61.66  ? 297 ARG A CD  1 
ATOM   1789  N NE  . ARG A 1 237 ? -64.051  8.980   72.472  1.00 67.51  ? 297 ARG A NE  1 
ATOM   1790  C CZ  . ARG A 1 237 ? -64.037  7.888   71.724  1.00 64.12  ? 297 ARG A CZ  1 
ATOM   1791  N NH1 . ARG A 1 237 ? -64.507  7.909   70.493  1.00 55.10  ? 297 ARG A NH1 1 
ATOM   1792  N NH2 . ARG A 1 237 ? -63.540  6.772   72.223  1.00 68.22  ? 297 ARG A NH2 1 
ATOM   1793  N N   . ALA A 1 238 ? -63.133  13.987  68.185  1.00 64.97  ? 298 ALA A N   1 
ATOM   1794  C CA  . ALA A 1 238 ? -63.921  14.818  67.253  1.00 58.67  ? 298 ALA A CA  1 
ATOM   1795  C C   . ALA A 1 238 ? -65.402  14.737  67.635  1.00 61.01  ? 298 ALA A C   1 
ATOM   1796  O O   . ALA A 1 238 ? -65.897  13.584  67.934  1.00 53.53  ? 298 ALA A O   1 
ATOM   1797  C CB  . ALA A 1 238 ? -63.688  14.340  65.846  1.00 59.89  ? 298 ALA A CB  1 
ATOM   1798  N N   . THR A 1 239 ? -66.090  15.892  67.594  1.00 56.21  ? 299 THR A N   1 
ATOM   1799  C CA  . THR A 1 239 ? -67.519  16.030  67.988  1.00 60.52  ? 299 THR A CA  1 
ATOM   1800  C C   . THR A 1 239 ? -68.354  16.538  66.805  1.00 71.82  ? 299 THR A C   1 
ATOM   1801  O O   . THR A 1 239 ? -67.758  16.964  65.784  1.00 78.97  ? 299 THR A O   1 
ATOM   1802  C CB  . THR A 1 239 ? -67.638  16.912  69.233  1.00 58.24  ? 299 THR A CB  1 
ATOM   1803  O OG1 . THR A 1 239 ? -67.329  18.257  68.863  1.00 62.67  ? 299 THR A OG1 1 
ATOM   1804  C CG2 . THR A 1 239 ? -66.728  16.435  70.342  1.00 63.45  ? 299 THR A CG2 1 
ATOM   1805  N N   . GLY A 1 240 ? -69.685  16.451  66.929  1.00 82.59  ? 300 GLY A N   1 
ATOM   1806  C CA  . GLY A 1 240 ? -70.654  17.041  65.980  1.00 102.38 ? 300 GLY A CA  1 
ATOM   1807  C C   . GLY A 1 240 ? -70.324  16.745  64.522  1.00 103.00 ? 300 GLY A C   1 
ATOM   1808  O O   . GLY A 1 240 ? -70.114  15.575  64.193  1.00 98.21  ? 300 GLY A O   1 
ATOM   1809  N N   . GLU A 1 241 ? -70.353  17.779  63.679  1.00 102.08 ? 301 GLU A N   1 
ATOM   1810  C CA  . GLU A 1 241 ? -70.018  17.793  62.228  1.00 99.18  ? 301 GLU A CA  1 
ATOM   1811  C C   . GLU A 1 241 ? -68.977  16.716  61.866  1.00 95.75  ? 301 GLU A C   1 
ATOM   1812  O O   . GLU A 1 241 ? -69.308  15.758  61.091  1.00 76.86  ? 301 GLU A O   1 
ATOM   1813  C CB  . GLU A 1 241 ? -69.508  19.204  61.865  1.00 113.05 ? 301 GLU A CB  1 
ATOM   1814  C CG  . GLU A 1 241 ? -68.629  19.901  62.930  1.00 112.76 ? 301 GLU A CG  1 
ATOM   1815  C CD  . GLU A 1 241 ? -69.309  20.910  63.860  1.00 113.30 ? 301 GLU A CD  1 
ATOM   1816  O OE1 . GLU A 1 241 ? -69.901  20.474  64.882  1.00 105.45 ? 301 GLU A OE1 1 
ATOM   1817  O OE2 . GLU A 1 241 ? -69.235  22.132  63.578  1.00 99.07  ? 301 GLU A OE2 1 
ATOM   1818  N N   . GLU A 1 242 ? -67.758  16.864  62.401  1.00 83.69  ? 302 GLU A N   1 
ATOM   1819  C CA  . GLU A 1 242 ? -66.577  16.074  61.971  1.00 74.05  ? 302 GLU A CA  1 
ATOM   1820  C C   . GLU A 1 242 ? -66.830  14.583  62.251  1.00 68.73  ? 302 GLU A C   1 
ATOM   1821  O O   . GLU A 1 242 ? -66.601  13.747  61.354  1.00 73.81  ? 302 GLU A O   1 
ATOM   1822  C CB  . GLU A 1 242 ? -65.303  16.586  62.645  1.00 74.41  ? 302 GLU A CB  1 
ATOM   1823  C CG  . GLU A 1 242 ? -64.048  16.193  61.869  1.00 78.47  ? 302 GLU A CG  1 
ATOM   1824  C CD  . GLU A 1 242 ? -62.736  16.267  62.640  1.00 82.15  ? 302 GLU A CD  1 
ATOM   1825  O OE1 . GLU A 1 242 ? -62.669  17.068  63.590  1.00 90.30  ? 302 GLU A OE1 1 
ATOM   1826  O OE2 . GLU A 1 242 ? -61.776  15.533  62.279  1.00 79.59  ? 302 GLU A OE2 1 
ATOM   1827  N N   . TYR A 1 243 ? -67.297  14.257  63.453  1.00 62.67  ? 303 TYR A N   1 
ATOM   1828  C CA  . TYR A 1 243 ? -67.667  12.877  63.858  1.00 60.86  ? 303 TYR A CA  1 
ATOM   1829  C C   . TYR A 1 243 ? -68.695  12.339  62.859  1.00 66.59  ? 303 TYR A C   1 
ATOM   1830  O O   . TYR A 1 243 ? -68.461  11.305  62.208  1.00 64.56  ? 303 TYR A O   1 
ATOM   1831  C CB  . TYR A 1 243 ? -68.203  12.869  65.292  1.00 57.84  ? 303 TYR A CB  1 
ATOM   1832  C CG  . TYR A 1 243 ? -68.626  11.522  65.800  1.00 59.34  ? 303 TYR A CG  1 
ATOM   1833  C CD1 . TYR A 1 243 ? -69.885  11.026  65.537  1.00 62.58  ? 303 TYR A CD1 1 
ATOM   1834  C CD2 . TYR A 1 243 ? -67.783  10.750  66.576  1.00 69.26  ? 303 TYR A CD2 1 
ATOM   1835  C CE1 . TYR A 1 243 ? -70.299  9.787   66.011  1.00 67.24  ? 303 TYR A CE1 1 
ATOM   1836  C CE2 . TYR A 1 243 ? -68.181  9.504   67.060  1.00 74.23  ? 303 TYR A CE2 1 
ATOM   1837  C CZ  . TYR A 1 243 ? -69.438  9.002   66.755  1.00 69.04  ? 303 TYR A CZ  1 
ATOM   1838  O OH  . TYR A 1 243 ? -69.837  7.788   67.247  1.00 64.06  ? 303 TYR A OH  1 
ATOM   1839  N N   . ASP A 1 244 ? -69.810  13.052  62.732  1.00 67.45  ? 304 ASP A N   1 
ATOM   1840  C CA  . ASP A 1 244 ? -71.019  12.582  62.011  1.00 69.60  ? 304 ASP A CA  1 
ATOM   1841  C C   . ASP A 1 244 ? -70.649  12.138  60.591  1.00 70.07  ? 304 ASP A C   1 
ATOM   1842  O O   . ASP A 1 244 ? -71.120  11.065  60.191  1.00 68.90  ? 304 ASP A O   1 
ATOM   1843  C CB  . ASP A 1 244 ? -72.106  13.655  62.012  1.00 66.51  ? 304 ASP A CB  1 
ATOM   1844  C CG  . ASP A 1 244 ? -72.810  13.832  63.353  1.00 66.45  ? 304 ASP A CG  1 
ATOM   1845  O OD1 . ASP A 1 244 ? -72.923  12.856  64.120  1.00 59.66  ? 304 ASP A OD1 1 
ATOM   1846  O OD2 . ASP A 1 244 ? -73.251  14.963  63.628  1.00 80.89  ? 304 ASP A OD2 1 
ATOM   1847  N N   . GLU A 1 245 ? -69.862  12.939  59.865  1.00 73.09  ? 305 GLU A N   1 
ATOM   1848  C CA  . GLU A 1 245 ? -69.496  12.669  58.444  1.00 70.60  ? 305 GLU A CA  1 
ATOM   1849  C C   . GLU A 1 245 ? -68.784  11.321  58.320  1.00 73.35  ? 305 GLU A C   1 
ATOM   1850  O O   . GLU A 1 245 ? -69.091  10.572  57.371  1.00 58.21  ? 305 GLU A O   1 
ATOM   1851  C CB  . GLU A 1 245 ? -68.559  13.726  57.883  1.00 66.71  ? 305 GLU A CB  1 
ATOM   1852  C CG  . GLU A 1 245 ? -69.273  14.984  57.485  1.00 76.03  ? 305 GLU A CG  1 
ATOM   1853  C CD  . GLU A 1 245 ? -68.629  16.230  58.062  1.00 95.46  ? 305 GLU A CD  1 
ATOM   1854  O OE1 . GLU A 1 245 ? -67.381  16.247  58.123  1.00 104.30 ? 305 GLU A OE1 1 
ATOM   1855  O OE2 . GLU A 1 245 ? -69.380  17.157  58.474  1.00 115.47 ? 305 GLU A OE2 1 
ATOM   1856  N N   . LEU A 1 246 ? -67.854  11.027  59.230  1.00 73.62  ? 306 LEU A N   1 
ATOM   1857  C CA  . LEU A 1 246 ? -67.153  9.721   59.223  1.00 78.79  ? 306 LEU A CA  1 
ATOM   1858  C C   . LEU A 1 246 ? -68.211  8.625   59.380  1.00 78.70  ? 306 LEU A C   1 
ATOM   1859  O O   . LEU A 1 246 ? -68.200  7.672   58.587  1.00 71.79  ? 306 LEU A O   1 
ATOM   1860  C CB  . LEU A 1 246 ? -66.105  9.679   60.337  1.00 74.10  ? 306 LEU A CB  1 
ATOM   1861  C CG  . LEU A 1 246 ? -65.175  8.471   60.322  1.00 63.78  ? 306 LEU A CG  1 
ATOM   1862  C CD1 . LEU A 1 246 ? -64.328  8.442   59.068  1.00 72.25  ? 306 LEU A CD1 1 
ATOM   1863  C CD2 . LEU A 1 246 ? -64.275  8.498   61.541  1.00 75.42  ? 306 LEU A CD2 1 
ATOM   1864  N N   . ILE A 1 247 ? -69.118  8.771   60.345  1.00 73.85  ? 307 ILE A N   1 
ATOM   1865  C CA  . ILE A 1 247 ? -70.131  7.717   60.613  1.00 73.00  ? 307 ILE A CA  1 
ATOM   1866  C C   . ILE A 1 247 ? -70.977  7.491   59.359  1.00 70.06  ? 307 ILE A C   1 
ATOM   1867  O O   . ILE A 1 247 ? -71.130  6.338   58.966  1.00 84.04  ? 307 ILE A O   1 
ATOM   1868  C CB  . ILE A 1 247 ? -70.955  8.076   61.856  1.00 74.56  ? 307 ILE A CB  1 
ATOM   1869  C CG1 . ILE A 1 247 ? -70.064  8.018   63.099  1.00 77.21  ? 307 ILE A CG1 1 
ATOM   1870  C CG2 . ILE A 1 247 ? -72.172  7.172   61.996  1.00 83.82  ? 307 ILE A CG2 1 
ATOM   1871  C CD1 . ILE A 1 247 ? -69.676  6.602   63.494  1.00 81.32  ? 307 ILE A CD1 1 
ATOM   1872  N N   . GLU A 1 248 ? -71.495  8.548   58.747  1.00 74.88  ? 308 GLU A N   1 
ATOM   1873  C CA  . GLU A 1 248 ? -72.504  8.392   57.667  1.00 79.36  ? 308 GLU A CA  1 
ATOM   1874  C C   . GLU A 1 248 ? -71.771  7.914   56.408  1.00 78.15  ? 308 GLU A C   1 
ATOM   1875  O O   . GLU A 1 248 ? -72.405  7.238   55.573  1.00 83.29  ? 308 GLU A O   1 
ATOM   1876  C CB  . GLU A 1 248 ? -73.384  9.642   57.544  1.00 80.41  ? 308 GLU A CB  1 
ATOM   1877  C CG  . GLU A 1 248 ? -72.744  10.880  56.956  1.00 83.16  ? 308 GLU A CG  1 
ATOM   1878  C CD  . GLU A 1 248 ? -73.670  12.106  57.051  1.00 98.77  ? 308 GLU A CD  1 
ATOM   1879  O OE1 . GLU A 1 248 ? -74.665  12.134  56.288  1.00 105.03 ? 308 GLU A OE1 1 
ATOM   1880  O OE2 . GLU A 1 248 ? -73.437  13.032  57.898  1.00 84.42  ? 308 GLU A OE2 1 
ATOM   1881  N N   . GLU A 1 249 ? -70.461  8.160   56.320  1.00 69.39  ? 309 GLU A N   1 
ATOM   1882  C CA  . GLU A 1 249 ? -69.607  7.630   55.222  1.00 58.99  ? 309 GLU A CA  1 
ATOM   1883  C C   . GLU A 1 249 ? -69.335  6.145   55.507  1.00 56.89  ? 309 GLU A C   1 
ATOM   1884  O O   . GLU A 1 249 ? -69.347  5.334   54.554  1.00 48.01  ? 309 GLU A O   1 
ATOM   1885  C CB  . GLU A 1 249 ? -68.320  8.445   55.085  1.00 59.07  ? 309 GLU A CB  1 
ATOM   1886  C CG  . GLU A 1 249 ? -67.177  7.652   54.467  1.00 63.65  ? 309 GLU A CG  1 
ATOM   1887  C CD  . GLU A 1 249 ? -65.906  8.386   54.122  1.00 68.31  ? 309 GLU A CD  1 
ATOM   1888  O OE1 . GLU A 1 249 ? -65.693  9.491   54.635  1.00 83.32  ? 309 GLU A OE1 1 
ATOM   1889  O OE2 . GLU A 1 249 ? -65.106  7.799   53.375  1.00 84.24  ? 309 GLU A OE2 1 
ATOM   1890  N N   . PHE A 1 250 ? -69.087  5.807   56.773  1.00 56.79  ? 310 PHE A N   1 
ATOM   1891  C CA  . PHE A 1 250 ? -68.897  4.412   57.245  1.00 57.68  ? 310 PHE A CA  1 
ATOM   1892  C C   . PHE A 1 250 ? -70.164  3.621   56.900  1.00 59.28  ? 310 PHE A C   1 
ATOM   1893  O O   . PHE A 1 250 ? -70.085  2.560   56.228  1.00 51.71  ? 310 PHE A O   1 
ATOM   1894  C CB  . PHE A 1 250 ? -68.566  4.353   58.739  1.00 54.08  ? 310 PHE A CB  1 
ATOM   1895  C CG  . PHE A 1 250 ? -68.492  2.944   59.259  1.00 57.00  ? 310 PHE A CG  1 
ATOM   1896  C CD1 . PHE A 1 250 ? -67.457  2.090   58.915  1.00 60.55  ? 310 PHE A CD1 1 
ATOM   1897  C CD2 . PHE A 1 250 ? -69.487  2.444   60.070  1.00 66.44  ? 310 PHE A CD2 1 
ATOM   1898  C CE1 . PHE A 1 250 ? -67.418  0.779   59.376  1.00 56.52  ? 310 PHE A CE1 1 
ATOM   1899  C CE2 . PHE A 1 250 ? -69.433  1.142   60.561  1.00 65.60  ? 310 PHE A CE2 1 
ATOM   1900  C CZ  . PHE A 1 250 ? -68.406  0.306   60.195  1.00 58.89  ? 310 PHE A CZ  1 
ATOM   1901  N N   . MET A 1 251 ? -71.318  4.178   57.271  1.00 60.38  ? 311 MET A N   1 
ATOM   1902  C CA  . MET A 1 251 ? -72.654  3.541   57.097  1.00 60.78  ? 311 MET A CA  1 
ATOM   1903  C C   . MET A 1 251 ? -72.961  3.413   55.593  1.00 55.46  ? 311 MET A C   1 
ATOM   1904  O O   . MET A 1 251 ? -73.479  2.355   55.176  1.00 44.15  ? 311 MET A O   1 
ATOM   1905  C CB  . MET A 1 251 ? -73.739  4.333   57.851  1.00 61.01  ? 311 MET A CB  1 
ATOM   1906  C CG  . MET A 1 251 ? -73.735  4.086   59.367  1.00 60.37  ? 311 MET A CG  1 
ATOM   1907  S SD  . MET A 1 251 ? -73.936  2.317   59.831  1.00 60.58  ? 311 MET A SD  1 
ATOM   1908  C CE  . MET A 1 251 ? -72.815  2.355   61.218  1.00 68.29  ? 311 MET A CE  1 
ATOM   1909  N N   . SER A 1 252 ? -72.644  4.439   54.806  1.00 54.61  ? 312 SER A N   1 
ATOM   1910  C CA  . SER A 1 252 ? -72.658  4.361   53.325  1.00 57.48  ? 312 SER A CA  1 
ATOM   1911  C C   . SER A 1 252 ? -71.844  3.143   52.875  1.00 60.99  ? 312 SER A C   1 
ATOM   1912  O O   . SER A 1 252 ? -72.406  2.245   52.233  1.00 57.34  ? 312 SER A O   1 
ATOM   1913  C CB  . SER A 1 252 ? -72.121  5.612   52.701  1.00 56.44  ? 312 SER A CB  1 
ATOM   1914  O OG  . SER A 1 252 ? -73.170  6.463   52.315  1.00 70.21  ? 312 SER A OG  1 
ATOM   1915  N N   . ALA A 1 253 ? -70.558  3.141   53.231  1.00 60.41  ? 313 ALA A N   1 
ATOM   1916  C CA  . ALA A 1 253 ? -69.510  2.234   52.714  1.00 62.86  ? 313 ALA A CA  1 
ATOM   1917  C C   . ALA A 1 253 ? -69.861  0.780   53.031  1.00 62.70  ? 313 ALA A C   1 
ATOM   1918  O O   . ALA A 1 253 ? -69.592  -0.105  52.196  1.00 59.70  ? 313 ALA A O   1 
ATOM   1919  C CB  . ALA A 1 253 ? -68.188  2.617   53.320  1.00 62.37  ? 313 ALA A CB  1 
ATOM   1920  N N   . VAL A 1 254 ? -70.399  0.546   54.223  1.00 62.89  ? 314 VAL A N   1 
ATOM   1921  C CA  . VAL A 1 254 ? -70.768  -0.816  54.689  1.00 61.25  ? 314 VAL A CA  1 
ATOM   1922  C C   . VAL A 1 254 ? -71.847  -1.336  53.742  1.00 62.14  ? 314 VAL A C   1 
ATOM   1923  O O   . VAL A 1 254 ? -71.736  -2.505  53.315  1.00 52.77  ? 314 VAL A O   1 
ATOM   1924  C CB  . VAL A 1 254 ? -71.238  -0.788  56.157  1.00 62.14  ? 314 VAL A CB  1 
ATOM   1925  C CG1 . VAL A 1 254 ? -71.734  -2.156  56.600  1.00 64.89  ? 314 VAL A CG1 1 
ATOM   1926  C CG2 . VAL A 1 254 ? -70.156  -0.295  57.111  1.00 57.49  ? 314 VAL A CG2 1 
ATOM   1927  N N   . LYS A 1 255 ? -72.816  -0.465  53.434  1.00 71.13  ? 315 LYS A N   1 
ATOM   1928  C CA  . LYS A 1 255 ? -74.019  -0.727  52.584  1.00 81.51  ? 315 LYS A CA  1 
ATOM   1929  C C   . LYS A 1 255 ? -73.556  -1.189  51.201  1.00 72.18  ? 315 LYS A C   1 
ATOM   1930  O O   . LYS A 1 255 ? -74.068  -2.248  50.742  1.00 54.69  ? 315 LYS A O   1 
ATOM   1931  C CB  . LYS A 1 255 ? -74.925  0.521   52.417  1.00 101.84 ? 315 LYS A CB  1 
ATOM   1932  C CG  . LYS A 1 255 ? -75.109  1.103   50.995  1.00 120.32 ? 315 LYS A CG  1 
ATOM   1933  C CD  . LYS A 1 255 ? -76.038  2.314   50.829  1.00 119.21 ? 315 LYS A CD  1 
ATOM   1934  C CE  . LYS A 1 255 ? -75.472  3.368   49.880  1.00 116.07 ? 315 LYS A CE  1 
ATOM   1935  N NZ  . LYS A 1 255 ? -75.443  4.732   50.475  1.00 103.54 ? 315 LYS A NZ  1 
ATOM   1936  N N   . GLN A 1 256 ? -72.665  -0.386  50.582  1.00 68.99  ? 316 GLN A N   1 
ATOM   1937  C CA  . GLN A 1 256 ? -72.184  -0.545  49.174  1.00 65.12  ? 316 GLN A CA  1 
ATOM   1938  C C   . GLN A 1 256 ? -71.421  -1.860  49.106  1.00 61.54  ? 316 GLN A C   1 
ATOM   1939  O O   . GLN A 1 256 ? -71.668  -2.633  48.184  1.00 61.59  ? 316 GLN A O   1 
ATOM   1940  C CB  . GLN A 1 256 ? -71.300  0.611   48.683  1.00 61.32  ? 316 GLN A CB  1 
ATOM   1941  C CG  . GLN A 1 256 ? -71.933  1.987   48.824  1.00 66.00  ? 316 GLN A CG  1 
ATOM   1942  C CD  . GLN A 1 256 ? -71.484  3.010   47.814  1.00 69.70  ? 316 GLN A CD  1 
ATOM   1943  O OE1 . GLN A 1 256 ? -72.011  3.076   46.712  1.00 82.73  ? 316 GLN A OE1 1 
ATOM   1944  N NE2 . GLN A 1 256 ? -70.573  3.878   48.221  1.00 75.31  ? 316 GLN A NE2 1 
ATOM   1945  N N   . PHE A 1 257 ? -70.586  -2.134  50.100  1.00 63.92  ? 317 PHE A N   1 
ATOM   1946  C CA  . PHE A 1 257 ? -69.663  -3.292  50.074  1.00 73.67  ? 317 PHE A CA  1 
ATOM   1947  C C   . PHE A 1 257 ? -70.454  -4.574  50.396  1.00 74.25  ? 317 PHE A C   1 
ATOM   1948  O O   . PHE A 1 257 ? -70.361  -5.548  49.615  1.00 66.29  ? 317 PHE A O   1 
ATOM   1949  C CB  . PHE A 1 257 ? -68.460  -3.035  50.994  1.00 79.48  ? 317 PHE A CB  1 
ATOM   1950  C CG  . PHE A 1 257 ? -67.145  -3.419  50.374  1.00 86.94  ? 317 PHE A CG  1 
ATOM   1951  C CD1 . PHE A 1 257 ? -66.612  -2.619  49.378  1.00 90.61  ? 317 PHE A CD1 1 
ATOM   1952  C CD2 . PHE A 1 257 ? -66.427  -4.531  50.788  1.00 92.33  ? 317 PHE A CD2 1 
ATOM   1953  C CE1 . PHE A 1 257 ? -65.420  -2.954  48.761  1.00 83.79  ? 317 PHE A CE1 1 
ATOM   1954  C CE2 . PHE A 1 257 ? -65.250  -4.872  50.151  1.00 85.87  ? 317 PHE A CE2 1 
ATOM   1955  C CZ  . PHE A 1 257 ? -64.752  -4.085  49.143  1.00 79.11  ? 317 PHE A CZ  1 
ATOM   1956  N N   . TYR A 1 258 ? -71.210  -4.593  51.504  1.00 71.56  ? 318 TYR A N   1 
ATOM   1957  C CA  . TYR A 1 258 ? -71.715  -5.847  52.121  1.00 64.18  ? 318 TYR A CA  1 
ATOM   1958  C C   . TYR A 1 258 ? -73.216  -6.013  51.838  1.00 61.83  ? 318 TYR A C   1 
ATOM   1959  O O   . TYR A 1 258 ? -73.740  -7.142  52.009  1.00 57.89  ? 318 TYR A O   1 
ATOM   1960  C CB  . TYR A 1 258 ? -71.310  -5.893  53.602  1.00 59.40  ? 318 TYR A CB  1 
ATOM   1961  C CG  . TYR A 1 258 ? -69.815  -5.790  53.850  1.00 62.94  ? 318 TYR A CG  1 
ATOM   1962  C CD1 . TYR A 1 258 ? -68.934  -6.732  53.322  1.00 57.83  ? 318 TYR A CD1 1 
ATOM   1963  C CD2 . TYR A 1 258 ? -69.265  -4.752  54.603  1.00 59.73  ? 318 TYR A CD2 1 
ATOM   1964  C CE1 . TYR A 1 258 ? -67.568  -6.648  53.522  1.00 56.19  ? 318 TYR A CE1 1 
ATOM   1965  C CE2 . TYR A 1 258 ? -67.898  -4.654  54.814  1.00 55.21  ? 318 TYR A CE2 1 
ATOM   1966  C CZ  . TYR A 1 258 ? -67.043  -5.605  54.269  1.00 58.81  ? 318 TYR A CZ  1 
ATOM   1967  O OH  . TYR A 1 258 ? -65.684  -5.509  54.437  1.00 54.36  ? 318 TYR A OH  1 
ATOM   1968  N N   . GLY A 1 259 ? -73.882  -4.950  51.377  1.00 57.77  ? 319 GLY A N   1 
ATOM   1969  C CA  . GLY A 1 259 ? -75.339  -4.939  51.134  1.00 58.41  ? 319 GLY A CA  1 
ATOM   1970  C C   . GLY A 1 259 ? -76.112  -4.501  52.367  1.00 61.02  ? 319 GLY A C   1 
ATOM   1971  O O   . GLY A 1 259 ? -75.512  -3.944  53.275  1.00 64.22  ? 319 GLY A O   1 
ATOM   1972  N N   . GLU A 1 260 ? -77.412  -4.755  52.406  1.00 68.61  ? 320 GLU A N   1 
ATOM   1973  C CA  . GLU A 1 260 ? -78.314  -4.305  53.495  1.00 65.95  ? 320 GLU A CA  1 
ATOM   1974  C C   . GLU A 1 260 ? -78.503  -5.434  54.526  1.00 61.11  ? 320 GLU A C   1 
ATOM   1975  O O   . GLU A 1 260 ? -78.550  -5.103  55.712  1.00 61.98  ? 320 GLU A O   1 
ATOM   1976  C CB  . GLU A 1 260 ? -79.626  -3.783  52.889  1.00 69.54  ? 320 GLU A CB  1 
ATOM   1977  C CG  . GLU A 1 260 ? -80.875  -4.033  53.742  1.00 76.38  ? 320 GLU A CG  1 
ATOM   1978  C CD  . GLU A 1 260 ? -80.973  -3.190  55.010  1.00 78.06  ? 320 GLU A CD  1 
ATOM   1979  O OE1 . GLU A 1 260 ? -79.987  -2.487  55.306  1.00 82.07  ? 320 GLU A OE1 1 
ATOM   1980  O OE2 . GLU A 1 260 ? -82.014  -3.205  55.690  1.00 70.14  ? 320 GLU A OE2 1 
ATOM   1981  N N   . LYS A 1 261 ? -78.526  -6.709  54.119  1.00 56.68  ? 321 LYS A N   1 
ATOM   1982  C CA  . LYS A 1 261 ? -78.699  -7.884  55.029  1.00 68.94  ? 321 LYS A CA  1 
ATOM   1983  C C   . LYS A 1 261 ? -77.538  -8.045  56.050  1.00 67.96  ? 321 LYS A C   1 
ATOM   1984  O O   . LYS A 1 261 ? -77.598  -8.936  56.924  1.00 58.43  ? 321 LYS A O   1 
ATOM   1985  C CB  . LYS A 1 261 ? -78.881  -9.155  54.198  1.00 70.66  ? 321 LYS A CB  1 
ATOM   1986  C CG  . LYS A 1 261 ? -80.170  -9.185  53.386  1.00 76.61  ? 321 LYS A CG  1 
ATOM   1987  C CD  . LYS A 1 261 ? -80.470  -10.526 52.742  1.00 73.13  ? 321 LYS A CD  1 
ATOM   1988  C CE  . LYS A 1 261 ? -80.724  -10.465 51.245  1.00 81.77  ? 321 LYS A CE  1 
ATOM   1989  N NZ  . LYS A 1 261 ? -81.574  -9.313  50.859  1.00 96.58  ? 321 LYS A NZ  1 
ATOM   1990  N N   . VAL A 1 262 ? -76.516  -7.200  55.999  1.00 65.15  ? 322 VAL A N   1 
ATOM   1991  C CA  . VAL A 1 262 ? -75.382  -7.259  56.956  1.00 71.47  ? 322 VAL A CA  1 
ATOM   1992  C C   . VAL A 1 262 ? -75.802  -6.622  58.287  1.00 66.29  ? 322 VAL A C   1 
ATOM   1993  O O   . VAL A 1 262 ? -76.194  -5.409  58.310  1.00 68.50  ? 322 VAL A O   1 
ATOM   1994  C CB  . VAL A 1 262 ? -74.108  -6.601  56.392  1.00 77.74  ? 322 VAL A CB  1 
ATOM   1995  C CG1 . VAL A 1 262 ? -74.228  -5.082  56.280  1.00 72.55  ? 322 VAL A CG1 1 
ATOM   1996  C CG2 . VAL A 1 262 ? -72.892  -7.009  57.219  1.00 81.40  ? 322 VAL A CG2 1 
ATOM   1997  N N   . LEU A 1 263 ? -75.678  -7.415  59.351  1.00 54.84  ? 323 LEU A N   1 
ATOM   1998  C CA  . LEU A 1 263 ? -75.907  -7.015  60.755  1.00 55.68  ? 323 LEU A CA  1 
ATOM   1999  C C   . LEU A 1 263 ? -74.772  -6.086  61.178  1.00 55.60  ? 323 LEU A C   1 
ATOM   2000  O O   . LEU A 1 263 ? -73.634  -6.479  61.017  1.00 71.05  ? 323 LEU A O   1 
ATOM   2001  C CB  . LEU A 1 263 ? -75.962  -8.275  61.625  1.00 54.14  ? 323 LEU A CB  1 
ATOM   2002  C CG  . LEU A 1 263 ? -76.195  -8.040  63.112  1.00 59.87  ? 323 LEU A CG  1 
ATOM   2003  C CD1 . LEU A 1 263 ? -77.221  -6.936  63.346  1.00 63.51  ? 323 LEU A CD1 1 
ATOM   2004  C CD2 . LEU A 1 263 ? -76.643  -9.341  63.802  1.00 68.87  ? 323 LEU A CD2 1 
ATOM   2005  N N   . ILE A 1 264 ? -75.091  -4.883  61.641  1.00 49.15  ? 324 ILE A N   1 
ATOM   2006  C CA  . ILE A 1 264 ? -74.135  -3.916  62.245  1.00 50.74  ? 324 ILE A CA  1 
ATOM   2007  C C   . ILE A 1 264 ? -74.487  -3.817  63.738  1.00 54.05  ? 324 ILE A C   1 
ATOM   2008  O O   . ILE A 1 264 ? -75.459  -3.084  64.075  1.00 51.01  ? 324 ILE A O   1 
ATOM   2009  C CB  . ILE A 1 264 ? -74.227  -2.544  61.544  1.00 54.52  ? 324 ILE A CB  1 
ATOM   2010  C CG1 . ILE A 1 264 ? -74.027  -2.656  60.030  1.00 53.27  ? 324 ILE A CG1 1 
ATOM   2011  C CG2 . ILE A 1 264 ? -73.277  -1.534  62.175  1.00 53.94  ? 324 ILE A CG2 1 
ATOM   2012  C CD1 . ILE A 1 264 ? -74.369  -1.381  59.266  1.00 53.26  ? 324 ILE A CD1 1 
ATOM   2013  N N   . GLN A 1 265 ? -73.739  -4.524  64.597  1.00 58.78  ? 325 GLN A N   1 
ATOM   2014  C CA  . GLN A 1 265 ? -73.876  -4.530  66.086  1.00 56.11  ? 325 GLN A CA  1 
ATOM   2015  C C   . GLN A 1 265 ? -72.969  -3.436  66.665  1.00 58.56  ? 325 GLN A C   1 
ATOM   2016  O O   . GLN A 1 265 ? -71.749  -3.594  66.622  1.00 56.88  ? 325 GLN A O   1 
ATOM   2017  C CB  . GLN A 1 265 ? -73.547  -5.909  66.649  1.00 49.62  ? 325 GLN A CB  1 
ATOM   2018  C CG  . GLN A 1 265 ? -73.580  -6.002  68.161  1.00 49.75  ? 325 GLN A CG  1 
ATOM   2019  C CD  . GLN A 1 265 ? -73.663  -7.467  68.547  1.00 58.54  ? 325 GLN A CD  1 
ATOM   2020  O OE1 . GLN A 1 265 ? -74.349  -8.249  67.895  1.00 58.22  ? 325 GLN A OE1 1 
ATOM   2021  N NE2 . GLN A 1 265 ? -72.958  -7.865  69.602  1.00 55.48  ? 325 GLN A NE2 1 
ATOM   2022  N N   . PHE A 1 266 ? -73.562  -2.327  67.107  1.00 55.47  ? 326 PHE A N   1 
ATOM   2023  C CA  . PHE A 1 266 ? -72.888  -1.237  67.841  1.00 50.66  ? 326 PHE A CA  1 
ATOM   2024  C C   . PHE A 1 266 ? -72.571  -1.710  69.262  1.00 54.29  ? 326 PHE A C   1 
ATOM   2025  O O   . PHE A 1 266 ? -73.446  -2.337  69.892  1.00 54.04  ? 326 PHE A O   1 
ATOM   2026  C CB  . PHE A 1 266 ? -73.771  0.003   67.910  1.00 52.48  ? 326 PHE A CB  1 
ATOM   2027  C CG  . PHE A 1 266 ? -74.011  0.639   66.576  1.00 59.96  ? 326 PHE A CG  1 
ATOM   2028  C CD1 . PHE A 1 266 ? -74.925  0.105   65.694  1.00 61.80  ? 326 PHE A CD1 1 
ATOM   2029  C CD2 . PHE A 1 266 ? -73.318  1.781   66.211  1.00 68.42  ? 326 PHE A CD2 1 
ATOM   2030  C CE1 . PHE A 1 266 ? -75.145  0.707   64.470  1.00 64.95  ? 326 PHE A CE1 1 
ATOM   2031  C CE2 . PHE A 1 266 ? -73.515  2.362   64.975  1.00 61.32  ? 326 PHE A CE2 1 
ATOM   2032  C CZ  . PHE A 1 266 ? -74.432  1.824   64.113  1.00 68.97  ? 326 PHE A CZ  1 
ATOM   2033  N N   . GLU A 1 267 ? -71.366  -1.380  69.747  1.00 57.45  ? 327 GLU A N   1 
ATOM   2034  C CA  . GLU A 1 267 ? -70.844  -1.738  71.095  1.00 56.39  ? 327 GLU A CA  1 
ATOM   2035  C C   . GLU A 1 267 ? -70.222  -0.493  71.729  1.00 57.11  ? 327 GLU A C   1 
ATOM   2036  O O   . GLU A 1 267 ? -69.441  0.196   71.073  1.00 56.84  ? 327 GLU A O   1 
ATOM   2037  C CB  . GLU A 1 267 ? -69.783  -2.835  71.007  1.00 58.28  ? 327 GLU A CB  1 
ATOM   2038  C CG  . GLU A 1 267 ? -70.320  -4.201  70.685  1.00 58.20  ? 327 GLU A CG  1 
ATOM   2039  C CD  . GLU A 1 267 ? -71.093  -4.862  71.807  1.00 70.92  ? 327 GLU A CD  1 
ATOM   2040  O OE1 . GLU A 1 267 ? -71.176  -4.285  72.922  1.00 74.83  ? 327 GLU A OE1 1 
ATOM   2041  O OE2 . GLU A 1 267 ? -71.618  -5.961  71.557  1.00 86.42  ? 327 GLU A OE2 1 
ATOM   2042  N N   . ASP A 1 268 ? -70.626  -0.199  72.954  1.00 60.43  ? 328 ASP A N   1 
ATOM   2043  C CA  . ASP A 1 268 ? -69.898  0.698   73.881  1.00 62.00  ? 328 ASP A CA  1 
ATOM   2044  C C   . ASP A 1 268 ? -69.713  2.087   73.254  1.00 53.81  ? 328 ASP A C   1 
ATOM   2045  O O   . ASP A 1 268 ? -68.596  2.614   73.314  1.00 53.06  ? 328 ASP A O   1 
ATOM   2046  C CB  . ASP A 1 268 ? -68.585  0.008   74.259  1.00 67.55  ? 328 ASP A CB  1 
ATOM   2047  C CG  . ASP A 1 268 ? -68.768  -1.319  74.994  1.00 67.35  ? 328 ASP A CG  1 
ATOM   2048  O OD1 . ASP A 1 268 ? -69.923  -1.696  75.293  1.00 70.05  ? 328 ASP A OD1 1 
ATOM   2049  O OD2 . ASP A 1 268 ? -67.753  -1.976  75.253  1.00 67.42  ? 328 ASP A OD2 1 
ATOM   2050  N N   . PHE A 1 269 ? -70.773  2.675   72.705  1.00 51.94  ? 329 PHE A N   1 
ATOM   2051  C CA  . PHE A 1 269 ? -70.827  4.124   72.405  1.00 52.58  ? 329 PHE A CA  1 
ATOM   2052  C C   . PHE A 1 269 ? -71.404  4.845   73.624  1.00 52.40  ? 329 PHE A C   1 
ATOM   2053  O O   . PHE A 1 269 ? -72.010  4.144   74.453  1.00 51.88  ? 329 PHE A O   1 
ATOM   2054  C CB  . PHE A 1 269 ? -71.696  4.387   71.177  1.00 58.17  ? 329 PHE A CB  1 
ATOM   2055  C CG  . PHE A 1 269 ? -71.107  3.941   69.863  1.00 61.77  ? 329 PHE A CG  1 
ATOM   2056  C CD1 . PHE A 1 269 ? -71.100  2.588   69.528  1.00 55.63  ? 329 PHE A CD1 1 
ATOM   2057  C CD2 . PHE A 1 269 ? -70.610  4.883   68.949  1.00 60.46  ? 329 PHE A CD2 1 
ATOM   2058  C CE1 . PHE A 1 269 ? -70.571  2.190   68.309  1.00 62.73  ? 329 PHE A CE1 1 
ATOM   2059  C CE2 . PHE A 1 269 ? -70.082  4.481   67.730  1.00 53.39  ? 329 PHE A CE2 1 
ATOM   2060  C CZ  . PHE A 1 269 ? -70.064  3.133   67.413  1.00 61.04  ? 329 PHE A CZ  1 
ATOM   2061  N N   . ALA A 1 270 ? -71.227  6.172   73.706  1.00 58.14  ? 330 ALA A N   1 
ATOM   2062  C CA  . ALA A 1 270 ? -71.859  7.071   74.704  1.00 62.46  ? 330 ALA A CA  1 
ATOM   2063  C C   . ALA A 1 270 ? -73.364  7.110   74.445  1.00 63.75  ? 330 ALA A C   1 
ATOM   2064  O O   . ALA A 1 270 ? -73.770  6.784   73.335  1.00 72.13  ? 330 ALA A O   1 
ATOM   2065  C CB  . ALA A 1 270 ? -71.277  8.459   74.643  1.00 63.72  ? 330 ALA A CB  1 
ATOM   2066  N N   . ASN A 1 271 ? -74.150  7.489   75.458  1.00 70.76  ? 331 ASN A N   1 
ATOM   2067  C CA  . ASN A 1 271 ? -75.611  7.733   75.374  1.00 78.65  ? 331 ASN A CA  1 
ATOM   2068  C C   . ASN A 1 271 ? -75.935  8.482   74.060  1.00 75.62  ? 331 ASN A C   1 
ATOM   2069  O O   . ASN A 1 271 ? -76.471  7.854   73.104  1.00 61.90  ? 331 ASN A O   1 
ATOM   2070  C CB  . ASN A 1 271 ? -76.122  8.446   76.639  1.00 87.36  ? 331 ASN A CB  1 
ATOM   2071  C CG  . ASN A 1 271 ? -75.388  9.739   77.000  1.00 101.34 ? 331 ASN A CG  1 
ATOM   2072  O OD1 . ASN A 1 271 ? -74.470  10.231  76.326  1.00 96.94  ? 331 ASN A OD1 1 
ATOM   2073  N ND2 . ASN A 1 271 ? -75.814  10.350  78.085  1.00 98.18  ? 331 ASN A ND2 1 
ATOM   2074  N N   . HIS A 1 272 ? -75.625  9.775   73.986  1.00 78.61  ? 332 HIS A N   1 
ATOM   2075  C CA  . HIS A 1 272 ? -76.146  10.640  72.900  1.00 79.94  ? 332 HIS A CA  1 
ATOM   2076  C C   . HIS A 1 272 ? -75.984  9.904   71.571  1.00 73.37  ? 332 HIS A C   1 
ATOM   2077  O O   . HIS A 1 272 ? -76.982  9.741   70.883  1.00 64.27  ? 332 HIS A O   1 
ATOM   2078  C CB  . HIS A 1 272 ? -75.489  12.027  72.883  1.00 94.07  ? 332 HIS A CB  1 
ATOM   2079  C CG  . HIS A 1 272 ? -76.316  13.006  72.110  1.00 104.80 ? 332 HIS A CG  1 
ATOM   2080  N ND1 . HIS A 1 272 ? -76.343  13.005  70.729  1.00 104.09 ? 332 HIS A ND1 1 
ATOM   2081  C CD2 . HIS A 1 272 ? -77.195  13.968  72.504  1.00 111.40 ? 332 HIS A CD2 1 
ATOM   2082  C CE1 . HIS A 1 272 ? -77.179  13.938  70.300  1.00 104.65 ? 332 HIS A CE1 1 
ATOM   2083  N NE2 . HIS A 1 272 ? -77.719  14.539  71.373  1.00 110.73 ? 332 HIS A NE2 1 
ATOM   2084  N N   . ASN A 1 273 ? -74.776  9.420   71.260  1.00 71.18  ? 333 ASN A N   1 
ATOM   2085  C CA  . ASN A 1 273 ? -74.448  8.748   69.976  1.00 68.39  ? 333 ASN A CA  1 
ATOM   2086  C C   . ASN A 1 273 ? -75.254  7.453   69.810  1.00 61.06  ? 333 ASN A C   1 
ATOM   2087  O O   . ASN A 1 273 ? -75.946  7.340   68.783  1.00 71.96  ? 333 ASN A O   1 
ATOM   2088  C CB  . ASN A 1 273 ? -72.951  8.450   69.837  1.00 74.75  ? 333 ASN A CB  1 
ATOM   2089  C CG  . ASN A 1 273 ? -72.116  9.699   69.678  1.00 76.63  ? 333 ASN A CG  1 
ATOM   2090  O OD1 . ASN A 1 273 ? -72.201  10.603  70.505  1.00 96.98  ? 333 ASN A OD1 1 
ATOM   2091  N ND2 . ASN A 1 273 ? -71.319  9.758   68.630  1.00 63.72  ? 333 ASN A ND2 1 
ATOM   2092  N N   . ALA A 1 274 ? -75.168  6.511   70.756  1.00 60.11  ? 334 ALA A N   1 
ATOM   2093  C CA  . ALA A 1 274 ? -75.734  5.137   70.642  1.00 65.56  ? 334 ALA A CA  1 
ATOM   2094  C C   . ALA A 1 274 ? -77.189  5.180   70.180  1.00 67.41  ? 334 ALA A C   1 
ATOM   2095  O O   . ALA A 1 274 ? -77.593  4.206   69.498  1.00 75.30  ? 334 ALA A O   1 
ATOM   2096  C CB  . ALA A 1 274 ? -75.637  4.376   71.943  1.00 63.48  ? 334 ALA A CB  1 
ATOM   2097  N N   . PHE A 1 275 ? -77.917  6.243   70.561  1.00 65.80  ? 335 PHE A N   1 
ATOM   2098  C CA  . PHE A 1 275 ? -79.354  6.488   70.252  1.00 66.84  ? 335 PHE A CA  1 
ATOM   2099  C C   . PHE A 1 275 ? -79.491  7.066   68.830  1.00 73.73  ? 335 PHE A C   1 
ATOM   2100  O O   . PHE A 1 275 ? -80.221  6.456   68.033  1.00 97.28  ? 335 PHE A O   1 
ATOM   2101  C CB  . PHE A 1 275 ? -80.034  7.345   71.335  1.00 69.85  ? 335 PHE A CB  1 
ATOM   2102  C CG  . PHE A 1 275 ? -80.291  6.642   72.654  1.00 77.00  ? 335 PHE A CG  1 
ATOM   2103  C CD1 . PHE A 1 275 ? -80.973  5.431   72.705  1.00 75.38  ? 335 PHE A CD1 1 
ATOM   2104  C CD2 . PHE A 1 275 ? -79.855  7.188   73.860  1.00 78.31  ? 335 PHE A CD2 1 
ATOM   2105  C CE1 . PHE A 1 275 ? -81.163  4.764   73.905  1.00 65.59  ? 335 PHE A CE1 1 
ATOM   2106  C CE2 . PHE A 1 275 ? -79.987  6.494   75.049  1.00 70.84  ? 335 PHE A CE2 1 
ATOM   2107  C CZ  . PHE A 1 275 ? -80.681  5.310   75.070  1.00 71.51  ? 335 PHE A CZ  1 
ATOM   2108  N N   . ASP A 1 276 ? -78.803  8.159   68.472  1.00 70.88  ? 336 ASP A N   1 
ATOM   2109  C CA  . ASP A 1 276 ? -78.915  8.747   67.103  1.00 67.07  ? 336 ASP A CA  1 
ATOM   2110  C C   . ASP A 1 276 ? -78.573  7.700   66.041  1.00 66.28  ? 336 ASP A C   1 
ATOM   2111  O O   . ASP A 1 276 ? -79.146  7.796   64.954  1.00 73.26  ? 336 ASP A O   1 
ATOM   2112  C CB  . ASP A 1 276 ? -78.042  9.978   66.891  1.00 65.66  ? 336 ASP A CB  1 
ATOM   2113  C CG  . ASP A 1 276 ? -78.387  11.045  67.908  1.00 78.56  ? 336 ASP A CG  1 
ATOM   2114  O OD1 . ASP A 1 276 ? -78.616  10.647  69.054  1.00 80.34  ? 336 ASP A OD1 1 
ATOM   2115  O OD2 . ASP A 1 276 ? -78.456  12.268  67.550  1.00 100.36 ? 336 ASP A OD2 1 
ATOM   2116  N N   . LEU A 1 277 ? -77.680  6.753   66.342  1.00 63.47  ? 337 LEU A N   1 
ATOM   2117  C CA  . LEU A 1 277 ? -77.250  5.697   65.386  1.00 72.14  ? 337 LEU A CA  1 
ATOM   2118  C C   . LEU A 1 277 ? -78.384  4.681   65.199  1.00 75.55  ? 337 LEU A C   1 
ATOM   2119  O O   . LEU A 1 277 ? -78.591  4.227   64.053  1.00 71.90  ? 337 LEU A O   1 
ATOM   2120  C CB  . LEU A 1 277 ? -75.969  5.020   65.881  1.00 78.07  ? 337 LEU A CB  1 
ATOM   2121  C CG  . LEU A 1 277 ? -74.770  5.949   66.107  1.00 81.93  ? 337 LEU A CG  1 
ATOM   2122  C CD1 . LEU A 1 277 ? -73.539  5.143   66.513  1.00 75.55  ? 337 LEU A CD1 1 
ATOM   2123  C CD2 . LEU A 1 277 ? -74.457  6.835   64.895  1.00 80.72  ? 337 LEU A CD2 1 
ATOM   2124  N N   . LEU A 1 278 ? -79.110  4.336   66.266  1.00 75.16  ? 338 LEU A N   1 
ATOM   2125  C CA  . LEU A 1 278 ? -80.284  3.425   66.181  1.00 65.26  ? 338 LEU A CA  1 
ATOM   2126  C C   . LEU A 1 278 ? -81.452  4.164   65.515  1.00 64.29  ? 338 LEU A C   1 
ATOM   2127  O O   . LEU A 1 278 ? -82.204  3.500   64.772  1.00 63.39  ? 338 LEU A O   1 
ATOM   2128  C CB  . LEU A 1 278 ? -80.660  2.907   67.581  1.00 61.51  ? 338 LEU A CB  1 
ATOM   2129  C CG  . LEU A 1 278 ? -80.107  1.539   67.993  1.00 64.72  ? 338 LEU A CG  1 
ATOM   2130  C CD1 . LEU A 1 278 ? -80.743  1.080   69.282  1.00 61.76  ? 338 LEU A CD1 1 
ATOM   2131  C CD2 . LEU A 1 278 ? -80.309  0.458   66.942  1.00 70.84  ? 338 LEU A CD2 1 
ATOM   2132  N N   . GLU A 1 279 ? -81.591  5.481   65.759  1.00 63.18  ? 339 GLU A N   1 
ATOM   2133  C CA  . GLU A 1 279 ? -82.658  6.356   65.196  1.00 59.68  ? 339 GLU A CA  1 
ATOM   2134  C C   . GLU A 1 279 ? -82.447  6.475   63.684  1.00 66.01  ? 339 GLU A C   1 
ATOM   2135  O O   . GLU A 1 279 ? -83.312  5.947   62.944  1.00 68.70  ? 339 GLU A O   1 
ATOM   2136  C CB  . GLU A 1 279 ? -82.630  7.730   65.877  1.00 65.52  ? 339 GLU A CB  1 
ATOM   2137  C CG  . GLU A 1 279 ? -83.623  8.784   65.376  1.00 72.15  ? 339 GLU A CG  1 
ATOM   2138  C CD  . GLU A 1 279 ? -83.089  9.794   64.337  1.00 83.45  ? 339 GLU A CD  1 
ATOM   2139  O OE1 . GLU A 1 279 ? -81.991  10.378  64.548  1.00 85.69  ? 339 GLU A OE1 1 
ATOM   2140  O OE2 . GLU A 1 279 ? -83.751  9.991   63.288  1.00 75.08  ? 339 GLU A OE2 1 
ATOM   2141  N N   . LYS A 1 280 ? -81.339  7.104   63.254  1.00 68.23  ? 340 LYS A N   1 
ATOM   2142  C CA  . LYS A 1 280 ? -81.017  7.419   61.833  1.00 67.44  ? 340 LYS A CA  1 
ATOM   2143  C C   . LYS A 1 280 ? -80.980  6.166   60.941  1.00 60.32  ? 340 LYS A C   1 
ATOM   2144  O O   . LYS A 1 280 ? -81.492  6.238   59.816  1.00 65.26  ? 340 LYS A O   1 
ATOM   2145  C CB  . LYS A 1 280 ? -79.635  8.059   61.732  1.00 71.63  ? 340 LYS A CB  1 
ATOM   2146  C CG  . LYS A 1 280 ? -79.597  9.506   61.287  1.00 85.51  ? 340 LYS A CG  1 
ATOM   2147  C CD  . LYS A 1 280 ? -78.195  9.953   60.909  1.00 88.11  ? 340 LYS A CD  1 
ATOM   2148  C CE  . LYS A 1 280 ? -77.711  11.126  61.743  1.00 95.81  ? 340 LYS A CE  1 
ATOM   2149  N NZ  . LYS A 1 280 ? -76.264  11.381  61.543  1.00 98.27  ? 340 LYS A NZ  1 
ATOM   2150  N N   . TYR A 1 281 ? -80.400  5.051   61.394  1.00 56.57  ? 341 TYR A N   1 
ATOM   2151  C CA  . TYR A 1 281 ? -80.032  3.923   60.493  1.00 59.16  ? 341 TYR A CA  1 
ATOM   2152  C C   . TYR A 1 281 ? -80.964  2.722   60.685  1.00 58.50  ? 341 TYR A C   1 
ATOM   2153  O O   . TYR A 1 281 ? -80.654  1.682   60.113  1.00 57.53  ? 341 TYR A O   1 
ATOM   2154  C CB  . TYR A 1 281 ? -78.535  3.599   60.630  1.00 62.91  ? 341 TYR A CB  1 
ATOM   2155  C CG  . TYR A 1 281 ? -77.633  4.758   60.263  1.00 62.54  ? 341 TYR A CG  1 
ATOM   2156  C CD1 . TYR A 1 281 ? -77.429  5.137   58.943  1.00 58.63  ? 341 TYR A CD1 1 
ATOM   2157  C CD2 . TYR A 1 281 ? -77.026  5.526   61.251  1.00 63.23  ? 341 TYR A CD2 1 
ATOM   2158  C CE1 . TYR A 1 281 ? -76.641  6.234   58.628  1.00 56.15  ? 341 TYR A CE1 1 
ATOM   2159  C CE2 . TYR A 1 281 ? -76.221  6.613   60.954  1.00 53.18  ? 341 TYR A CE2 1 
ATOM   2160  C CZ  . TYR A 1 281 ? -76.035  6.969   59.632  1.00 53.29  ? 341 TYR A CZ  1 
ATOM   2161  O OH  . TYR A 1 281 ? -75.259  8.041   59.319  1.00 48.03  ? 341 TYR A OH  1 
ATOM   2162  N N   . SER A 1 282 ? -82.084  2.867   61.402  1.00 64.48  ? 342 SER A N   1 
ATOM   2163  C CA  . SER A 1 282 ? -83.104  1.797   61.578  1.00 65.26  ? 342 SER A CA  1 
ATOM   2164  C C   . SER A 1 282 ? -83.789  1.522   60.245  1.00 60.71  ? 342 SER A C   1 
ATOM   2165  O O   . SER A 1 282 ? -84.097  0.354   59.976  1.00 69.71  ? 342 SER A O   1 
ATOM   2166  C CB  . SER A 1 282 ? -84.110  2.156   62.620  1.00 68.17  ? 342 SER A CB  1 
ATOM   2167  O OG  . SER A 1 282 ? -83.501  2.112   63.903  1.00 76.56  ? 342 SER A OG  1 
ATOM   2168  N N   . LYS A 1 283 ? -84.004  2.560   59.437  1.00 66.85  ? 343 LYS A N   1 
ATOM   2169  C CA  . LYS A 1 283 ? -84.745  2.390   58.163  1.00 76.26  ? 343 LYS A CA  1 
ATOM   2170  C C   . LYS A 1 283 ? -83.781  1.897   57.081  1.00 77.22  ? 343 LYS A C   1 
ATOM   2171  O O   . LYS A 1 283 ? -84.113  0.828   56.523  1.00 77.38  ? 343 LYS A O   1 
ATOM   2172  C CB  . LYS A 1 283 ? -85.669  3.594   57.969  1.00 83.42  ? 343 LYS A CB  1 
ATOM   2173  C CG  . LYS A 1 283 ? -86.577  3.753   59.193  1.00 98.55  ? 343 LYS A CG  1 
ATOM   2174  C CD  . LYS A 1 283 ? -88.105  3.826   58.967  1.00 108.09 ? 343 LYS A CD  1 
ATOM   2175  C CE  . LYS A 1 283 ? -88.636  5.241   58.834  1.00 102.43 ? 343 LYS A CE  1 
ATOM   2176  N NZ  . LYS A 1 283 ? -89.940  5.406   59.517  1.00 96.01  ? 343 LYS A NZ  1 
ATOM   2177  N N   . SER A 1 284 ? -82.624  2.532   56.869  1.00 72.32  ? 344 SER A N   1 
ATOM   2178  C CA  . SER A 1 284 ? -81.675  2.166   55.785  1.00 66.43  ? 344 SER A CA  1 
ATOM   2179  C C   . SER A 1 284 ? -80.974  0.805   56.052  1.00 60.23  ? 344 SER A C   1 
ATOM   2180  O O   . SER A 1 284 ? -80.619  0.147   55.059  1.00 50.34  ? 344 SER A O   1 
ATOM   2181  C CB  . SER A 1 284 ? -80.669  3.287   55.548  1.00 63.96  ? 344 SER A CB  1 
ATOM   2182  O OG  . SER A 1 284 ? -80.324  3.940   56.767  1.00 60.17  ? 344 SER A OG  1 
ATOM   2183  N N   . HIS A 1 285 ? -80.721  0.417   57.309  1.00 57.70  ? 345 HIS A N   1 
ATOM   2184  C CA  . HIS A 1 285 ? -79.742  -0.656  57.680  1.00 61.32  ? 345 HIS A CA  1 
ATOM   2185  C C   . HIS A 1 285 ? -80.326  -1.644  58.702  1.00 57.23  ? 345 HIS A C   1 
ATOM   2186  O O   . HIS A 1 285 ? -81.384  -1.359  59.303  1.00 68.31  ? 345 HIS A O   1 
ATOM   2187  C CB  . HIS A 1 285 ? -78.431  -0.072  58.229  1.00 63.16  ? 345 HIS A CB  1 
ATOM   2188  C CG  . HIS A 1 285 ? -77.666  0.861   57.336  1.00 61.39  ? 345 HIS A CG  1 
ATOM   2189  N ND1 . HIS A 1 285 ? -78.082  1.335   56.113  1.00 66.93  ? 345 HIS A ND1 1 
ATOM   2190  C CD2 . HIS A 1 285 ? -76.444  1.395   57.505  1.00 61.77  ? 345 HIS A CD2 1 
ATOM   2191  C CE1 . HIS A 1 285 ? -77.193  2.159   55.615  1.00 68.24  ? 345 HIS A CE1 1 
ATOM   2192  N NE2 . HIS A 1 285 ? -76.172  2.175   56.423  1.00 59.26  ? 345 HIS A NE2 1 
ATOM   2193  N N   . LEU A 1 286 ? -79.685  -2.801  58.868  1.00 52.13  ? 346 LEU A N   1 
ATOM   2194  C CA  . LEU A 1 286 ? -80.036  -3.781  59.933  1.00 49.16  ? 346 LEU A CA  1 
ATOM   2195  C C   . LEU A 1 286 ? -79.094  -3.516  61.115  1.00 56.39  ? 346 LEU A C   1 
ATOM   2196  O O   . LEU A 1 286 ? -78.037  -4.136  61.201  1.00 58.33  ? 346 LEU A O   1 
ATOM   2197  C CB  . LEU A 1 286 ? -79.924  -5.198  59.370  1.00 45.42  ? 346 LEU A CB  1 
ATOM   2198  C CG  . LEU A 1 286 ? -80.039  -6.357  60.364  1.00 49.96  ? 346 LEU A CG  1 
ATOM   2199  C CD1 . LEU A 1 286 ? -81.436  -6.501  60.886  1.00 60.01  ? 346 LEU A CD1 1 
ATOM   2200  C CD2 . LEU A 1 286 ? -79.647  -7.682  59.740  1.00 52.15  ? 346 LEU A CD2 1 
ATOM   2201  N N   . VAL A 1 287 ? -79.454  -2.549  61.964  1.00 66.69  ? 347 VAL A N   1 
ATOM   2202  C CA  . VAL A 1 287 ? -78.639  -2.029  63.107  1.00 60.68  ? 347 VAL A CA  1 
ATOM   2203  C C   . VAL A 1 287 ? -79.195  -2.628  64.415  1.00 54.56  ? 347 VAL A C   1 
ATOM   2204  O O   . VAL A 1 287 ? -80.409  -2.830  64.516  1.00 56.15  ? 347 VAL A O   1 
ATOM   2205  C CB  . VAL A 1 287 ? -78.666  -0.484  63.126  1.00 63.89  ? 347 VAL A CB  1 
ATOM   2206  C CG1 . VAL A 1 287 ? -80.086  0.082   63.204  1.00 58.01  ? 347 VAL A CG1 1 
ATOM   2207  C CG2 . VAL A 1 287 ? -77.865  0.092   64.271  1.00 69.13  ? 347 VAL A CG2 1 
ATOM   2208  N N   . PHE A 1 288 ? -78.335  -2.874  65.399  1.00 50.33  ? 348 PHE A N   1 
ATOM   2209  C CA  . PHE A 1 288 ? -78.658  -3.537  66.694  1.00 48.86  ? 348 PHE A CA  1 
ATOM   2210  C C   . PHE A 1 288 ? -77.656  -3.008  67.696  1.00 50.46  ? 348 PHE A C   1 
ATOM   2211  O O   . PHE A 1 288 ? -76.538  -2.864  67.254  1.00 67.30  ? 348 PHE A O   1 
ATOM   2212  C CB  . PHE A 1 288 ? -78.536  -5.063  66.578  1.00 50.27  ? 348 PHE A CB  1 
ATOM   2213  C CG  . PHE A 1 288 ? -78.578  -5.798  67.887  1.00 50.98  ? 348 PHE A CG  1 
ATOM   2214  C CD1 . PHE A 1 288 ? -79.767  -5.975  68.567  1.00 58.34  ? 348 PHE A CD1 1 
ATOM   2215  C CD2 . PHE A 1 288 ? -77.424  -6.309  68.437  1.00 60.53  ? 348 PHE A CD2 1 
ATOM   2216  C CE1 . PHE A 1 288 ? -79.792  -6.647  69.776  1.00 66.08  ? 348 PHE A CE1 1 
ATOM   2217  C CE2 . PHE A 1 288 ? -77.444  -6.989  69.646  1.00 61.59  ? 348 PHE A CE2 1 
ATOM   2218  C CZ  . PHE A 1 288 ? -78.628  -7.150  70.314  1.00 64.99  ? 348 PHE A CZ  1 
ATOM   2219  N N   . ASN A 1 289 ? -78.015  -2.705  68.941  1.00 51.42  ? 349 ASN A N   1 
ATOM   2220  C CA  . ASN A 1 289 ? -77.083  -2.073  69.928  1.00 53.52  ? 349 ASN A CA  1 
ATOM   2221  C C   . ASN A 1 289 ? -76.995  -2.989  71.148  1.00 52.02  ? 349 ASN A C   1 
ATOM   2222  O O   . ASN A 1 289 ? -78.002  -3.137  71.818  1.00 66.09  ? 349 ASN A O   1 
ATOM   2223  C CB  . ASN A 1 289 ? -77.492  -0.627  70.272  1.00 50.82  ? 349 ASN A CB  1 
ATOM   2224  C CG  . ASN A 1 289 ? -76.496  0.083   71.167  1.00 56.54  ? 349 ASN A CG  1 
ATOM   2225  O OD1 . ASN A 1 289 ? -76.220  -0.392  72.255  1.00 62.98  ? 349 ASN A OD1 1 
ATOM   2226  N ND2 . ASN A 1 289 ? -75.999  1.245   70.764  1.00 63.81  ? 349 ASN A ND2 1 
ATOM   2227  N N   . ASP A 1 290 ? -75.838  -3.583  71.432  1.00 53.43  ? 350 ASP A N   1 
ATOM   2228  C CA  . ASP A 1 290 ? -75.721  -4.637  72.481  1.00 56.15  ? 350 ASP A CA  1 
ATOM   2229  C C   . ASP A 1 290 ? -76.052  -4.025  73.852  1.00 60.38  ? 350 ASP A C   1 
ATOM   2230  O O   . ASP A 1 290 ? -76.700  -4.719  74.676  1.00 58.19  ? 350 ASP A O   1 
ATOM   2231  C CB  . ASP A 1 290 ? -74.346  -5.313  72.443  1.00 51.77  ? 350 ASP A CB  1 
ATOM   2232  C CG  . ASP A 1 290 ? -74.385  -6.801  72.752  1.00 57.26  ? 350 ASP A CG  1 
ATOM   2233  O OD1 . ASP A 1 290 ? -75.486  -7.366  72.811  1.00 59.15  ? 350 ASP A OD1 1 
ATOM   2234  O OD2 . ASP A 1 290 ? -73.314  -7.386  72.932  1.00 59.34  ? 350 ASP A OD2 1 
ATOM   2235  N N   . ASP A 1 291 ? -75.676  -2.755  74.061  1.00 61.17  ? 351 ASP A N   1 
ATOM   2236  C CA  . ASP A 1 291 ? -75.825  -2.035  75.357  1.00 61.01  ? 351 ASP A CA  1 
ATOM   2237  C C   . ASP A 1 291 ? -77.308  -1.730  75.613  1.00 58.81  ? 351 ASP A C   1 
ATOM   2238  O O   . ASP A 1 291 ? -77.782  -1.971  76.730  1.00 62.33  ? 351 ASP A O   1 
ATOM   2239  C CB  . ASP A 1 291 ? -74.997  -0.752  75.379  1.00 70.02  ? 351 ASP A CB  1 
ATOM   2240  C CG  . ASP A 1 291 ? -73.638  -0.844  74.693  1.00 80.88  ? 351 ASP A CG  1 
ATOM   2241  O OD1 . ASP A 1 291 ? -72.970  -1.888  74.869  1.00 75.06  ? 351 ASP A OD1 1 
ATOM   2242  O OD2 . ASP A 1 291 ? -73.261  0.148   73.968  1.00 82.26  ? 351 ASP A OD2 1 
ATOM   2243  N N   . ILE A 1 292 ? -78.020  -1.214  74.616  1.00 59.33  ? 352 ILE A N   1 
ATOM   2244  C CA  . ILE A 1 292 ? -79.450  -0.792  74.751  1.00 60.71  ? 352 ILE A CA  1 
ATOM   2245  C C   . ILE A 1 292 ? -80.329  -2.042  74.616  1.00 55.55  ? 352 ILE A C   1 
ATOM   2246  O O   . ILE A 1 292 ? -80.959  -2.436  75.608  1.00 58.78  ? 352 ILE A O   1 
ATOM   2247  C CB  . ILE A 1 292 ? -79.822  0.318   73.736  1.00 55.46  ? 352 ILE A CB  1 
ATOM   2248  C CG1 . ILE A 1 292 ? -78.912  1.543   73.882  1.00 57.24  ? 352 ILE A CG1 1 
ATOM   2249  C CG2 . ILE A 1 292 ? -81.281  0.714   73.853  1.00 51.63  ? 352 ILE A CG2 1 
ATOM   2250  C CD1 . ILE A 1 292 ? -78.957  2.507   72.712  1.00 57.16  ? 352 ILE A CD1 1 
ATOM   2251  N N   . GLN A 1 293 ? -80.316  -2.657  73.439  1.00 49.57  ? 353 GLN A N   1 
ATOM   2252  C CA  . GLN A 1 293 ? -81.242  -3.748  73.035  1.00 54.59  ? 353 GLN A CA  1 
ATOM   2253  C C   . GLN A 1 293 ? -80.792  -5.111  73.606  1.00 55.44  ? 353 GLN A C   1 
ATOM   2254  O O   . GLN A 1 293 ? -81.653  -5.868  74.087  1.00 53.15  ? 353 GLN A O   1 
ATOM   2255  C CB  . GLN A 1 293 ? -81.387  -3.766  71.506  1.00 52.60  ? 353 GLN A CB  1 
ATOM   2256  C CG  . GLN A 1 293 ? -82.028  -2.506  70.935  1.00 52.34  ? 353 GLN A CG  1 
ATOM   2257  C CD  . GLN A 1 293 ? -81.833  -2.278  69.454  1.00 49.82  ? 353 GLN A CD  1 
ATOM   2258  O OE1 . GLN A 1 293 ? -80.851  -2.665  68.836  1.00 47.70  ? 353 GLN A OE1 1 
ATOM   2259  N NE2 . GLN A 1 293 ? -82.722  -1.509  68.884  1.00 50.39  ? 353 GLN A NE2 1 
ATOM   2260  N N   . GLY A 1 294 ? -79.505  -5.436  73.566  1.00 57.71  ? 354 GLY A N   1 
ATOM   2261  C CA  . GLY A 1 294 ? -79.030  -6.792  73.918  1.00 59.23  ? 354 GLY A CA  1 
ATOM   2262  C C   . GLY A 1 294 ? -79.160  -7.058  75.409  1.00 56.25  ? 354 GLY A C   1 
ATOM   2263  O O   . GLY A 1 294 ? -79.612  -8.164  75.788  1.00 43.36  ? 354 GLY A O   1 
ATOM   2264  N N   . THR A 1 295 ? -78.776  -6.060  76.215  1.00 57.07  ? 355 THR A N   1 
ATOM   2265  C CA  . THR A 1 295 ? -78.817  -6.085  77.700  1.00 55.73  ? 355 THR A CA  1 
ATOM   2266  C C   . THR A 1 295 ? -80.291  -6.097  78.134  1.00 62.45  ? 355 THR A C   1 
ATOM   2267  O O   . THR A 1 295 ? -80.681  -7.008  78.905  1.00 60.41  ? 355 THR A O   1 
ATOM   2268  C CB  . THR A 1 295 ? -78.006  -4.908  78.267  1.00 53.89  ? 355 THR A CB  1 
ATOM   2269  O OG1 . THR A 1 295 ? -76.695  -4.914  77.689  1.00 46.98  ? 355 THR A OG1 1 
ATOM   2270  C CG2 . THR A 1 295 ? -77.886  -4.923  79.773  1.00 47.08  ? 355 THR A CG2 1 
ATOM   2271  N N   . ALA A 1 296 ? -81.087  -5.147  77.627  1.00 62.96  ? 356 ALA A N   1 
ATOM   2272  C CA  . ALA A 1 296 ? -82.552  -5.101  77.820  1.00 58.72  ? 356 ALA A CA  1 
ATOM   2273  C C   . ALA A 1 296 ? -83.114  -6.507  77.657  1.00 54.26  ? 356 ALA A C   1 
ATOM   2274  O O   . ALA A 1 296 ? -83.865  -6.945  78.517  1.00 61.54  ? 356 ALA A O   1 
ATOM   2275  C CB  . ALA A 1 296 ? -83.186  -4.149  76.843  1.00 59.59  ? 356 ALA A CB  1 
ATOM   2276  N N   . SER A 1 297 ? -82.716  -7.193  76.599  1.00 53.99  ? 357 SER A N   1 
ATOM   2277  C CA  . SER A 1 297 ? -83.242  -8.525  76.229  1.00 59.22  ? 357 SER A CA  1 
ATOM   2278  C C   . SER A 1 297 ? -82.950  -9.540  77.338  1.00 53.25  ? 357 SER A C   1 
ATOM   2279  O O   . SER A 1 297 ? -83.882  -10.226 77.769  1.00 52.72  ? 357 SER A O   1 
ATOM   2280  C CB  . SER A 1 297 ? -82.678  -8.971  74.918  1.00 64.20  ? 357 SER A CB  1 
ATOM   2281  O OG  . SER A 1 297 ? -83.418  -10.072 74.426  1.00 69.63  ? 357 SER A OG  1 
ATOM   2282  N N   . VAL A 1 298 ? -81.705  -9.633  77.793  1.00 51.67  ? 358 VAL A N   1 
ATOM   2283  C CA  . VAL A 1 298 ? -81.269  -10.704 78.747  1.00 52.55  ? 358 VAL A CA  1 
ATOM   2284  C C   . VAL A 1 298 ? -81.815  -10.418 80.149  1.00 52.16  ? 358 VAL A C   1 
ATOM   2285  O O   . VAL A 1 298 ? -82.051  -11.382 80.924  1.00 51.13  ? 358 VAL A O   1 
ATOM   2286  C CB  . VAL A 1 298 ? -79.740  -10.831 78.783  1.00 48.71  ? 358 VAL A CB  1 
ATOM   2287  C CG1 . VAL A 1 298 ? -79.064  -9.575  79.330  1.00 47.67  ? 358 VAL A CG1 1 
ATOM   2288  C CG2 . VAL A 1 298 ? -79.313  -12.073 79.541  1.00 51.72  ? 358 VAL A CG2 1 
ATOM   2289  N N   . VAL A 1 299 ? -81.951  -9.135  80.473  1.00 50.04  ? 359 VAL A N   1 
ATOM   2290  C CA  . VAL A 1 299 ? -82.492  -8.678  81.775  1.00 52.81  ? 359 VAL A CA  1 
ATOM   2291  C C   . VAL A 1 299 ? -83.959  -9.110  81.846  1.00 53.80  ? 359 VAL A C   1 
ATOM   2292  O O   . VAL A 1 299 ? -84.336  -9.740  82.851  1.00 53.99  ? 359 VAL A O   1 
ATOM   2293  C CB  . VAL A 1 299 ? -82.329  -7.159  81.957  1.00 50.22  ? 359 VAL A CB  1 
ATOM   2294  C CG1 . VAL A 1 299 ? -83.139  -6.679  83.141  1.00 50.88  ? 359 VAL A CG1 1 
ATOM   2295  C CG2 . VAL A 1 299 ? -80.878  -6.771  82.133  1.00 49.11  ? 359 VAL A CG2 1 
ATOM   2296  N N   . LEU A 1 300 ? -84.746  -8.776  80.825  1.00 54.82  ? 360 LEU A N   1 
ATOM   2297  C CA  . LEU A 1 300 ? -86.175  -9.157  80.751  1.00 58.96  ? 360 LEU A CA  1 
ATOM   2298  C C   . LEU A 1 300 ? -86.273  -10.676 80.949  1.00 54.43  ? 360 LEU A C   1 
ATOM   2299  O O   . LEU A 1 300 ? -87.138  -11.102 81.706  1.00 59.51  ? 360 LEU A O   1 
ATOM   2300  C CB  . LEU A 1 300 ? -86.774  -8.697  79.413  1.00 62.28  ? 360 LEU A CB  1 
ATOM   2301  C CG  . LEU A 1 300 ? -88.280  -8.910  79.201  1.00 59.91  ? 360 LEU A CG  1 
ATOM   2302  C CD1 . LEU A 1 300 ? -89.108  -7.996  80.100  1.00 64.51  ? 360 LEU A CD1 1 
ATOM   2303  C CD2 . LEU A 1 300 ? -88.661  -8.689  77.753  1.00 55.02  ? 360 LEU A CD2 1 
ATOM   2304  N N   . ALA A 1 301 ? -85.398  -11.456 80.324  1.00 53.20  ? 361 ALA A N   1 
ATOM   2305  C CA  . ALA A 1 301 ? -85.388  -12.934 80.433  1.00 55.43  ? 361 ALA A CA  1 
ATOM   2306  C C   . ALA A 1 301 ? -85.070  -13.330 81.878  1.00 55.65  ? 361 ALA A C   1 
ATOM   2307  O O   . ALA A 1 301 ? -85.640  -14.307 82.370  1.00 61.35  ? 361 ALA A O   1 
ATOM   2308  C CB  . ALA A 1 301 ? -84.379  -13.518 79.472  1.00 57.61  ? 361 ALA A CB  1 
ATOM   2309  N N   . GLY A 1 302 ? -84.139  -12.624 82.507  1.00 51.18  ? 362 GLY A N   1 
ATOM   2310  C CA  . GLY A 1 302 ? -83.790  -12.858 83.915  1.00 52.35  ? 362 GLY A CA  1 
ATOM   2311  C C   . GLY A 1 302 ? -84.977  -12.608 84.832  1.00 53.21  ? 362 GLY A C   1 
ATOM   2312  O O   . GLY A 1 302 ? -85.256  -13.488 85.675  1.00 48.18  ? 362 GLY A O   1 
ATOM   2313  N N   . LEU A 1 303 ? -85.652  -11.461 84.662  1.00 49.61  ? 363 LEU A N   1 
ATOM   2314  C CA  . LEU A 1 303 ? -86.892  -11.121 85.391  1.00 47.21  ? 363 LEU A CA  1 
ATOM   2315  C C   . LEU A 1 303 ? -87.913  -12.244 85.229  1.00 46.01  ? 363 LEU A C   1 
ATOM   2316  O O   . LEU A 1 303 ? -88.338  -12.748 86.255  1.00 50.23  ? 363 LEU A O   1 
ATOM   2317  C CB  . LEU A 1 303 ? -87.415  -9.783  84.884  1.00 49.50  ? 363 LEU A CB  1 
ATOM   2318  C CG  . LEU A 1 303 ? -86.522  -8.625  85.316  1.00 59.17  ? 363 LEU A CG  1 
ATOM   2319  C CD1 . LEU A 1 303 ? -86.889  -7.309  84.651  1.00 66.35  ? 363 LEU A CD1 1 
ATOM   2320  C CD2 . LEU A 1 303 ? -86.653  -8.473  86.808  1.00 69.46  ? 363 LEU A CD2 1 
ATOM   2321  N N   . LEU A 1 304 ? -88.237  -12.669 84.007  1.00 45.69  ? 364 LEU A N   1 
ATOM   2322  C CA  . LEU A 1 304 ? -89.240  -13.747 83.753  1.00 50.96  ? 364 LEU A CA  1 
ATOM   2323  C C   . LEU A 1 304 ? -88.807  -15.040 84.455  1.00 52.67  ? 364 LEU A C   1 
ATOM   2324  O O   . LEU A 1 304 ? -89.691  -15.757 84.952  1.00 57.18  ? 364 LEU A O   1 
ATOM   2325  C CB  . LEU A 1 304 ? -89.423  -13.999 82.250  1.00 51.35  ? 364 LEU A CB  1 
ATOM   2326  C CG  . LEU A 1 304 ? -90.447  -13.135 81.508  1.00 51.97  ? 364 LEU A CG  1 
ATOM   2327  C CD1 . LEU A 1 304 ? -90.445  -11.667 81.939  1.00 51.78  ? 364 LEU A CD1 1 
ATOM   2328  C CD2 . LEU A 1 304 ? -90.178  -13.237 80.010  1.00 55.14  ? 364 LEU A CD2 1 
ATOM   2329  N N   . ALA A 1 305 ? -87.506  -15.317 84.485  1.00 57.75  ? 365 ALA A N   1 
ATOM   2330  C CA  . ALA A 1 305 ? -86.916  -16.544 85.076  1.00 58.83  ? 365 ALA A CA  1 
ATOM   2331  C C   . ALA A 1 305 ? -87.010  -16.452 86.598  1.00 55.18  ? 365 ALA A C   1 
ATOM   2332  O O   . ALA A 1 305 ? -87.236  -17.530 87.237  1.00 45.69  ? 365 ALA A O   1 
ATOM   2333  C CB  . ALA A 1 305 ? -85.481  -16.727 84.616  1.00 59.15  ? 365 ALA A CB  1 
ATOM   2334  N N   . ALA A 1 306 ? -86.841  -15.222 87.129  1.00 52.76  ? 366 ALA A N   1 
ATOM   2335  C CA  . ALA A 1 306 ? -86.889  -14.905 88.574  1.00 58.66  ? 366 ALA A CA  1 
ATOM   2336  C C   . ALA A 1 306 ? -88.309  -15.174 89.070  1.00 66.56  ? 366 ALA A C   1 
ATOM   2337  O O   . ALA A 1 306 ? -88.481  -15.841 90.137  1.00 76.88  ? 366 ALA A O   1 
ATOM   2338  C CB  . ALA A 1 306 ? -86.487  -13.470 88.832  1.00 58.67  ? 366 ALA A CB  1 
ATOM   2339  N N   . LEU A 1 307 ? -89.289  -14.708 88.287  1.00 59.05  ? 367 LEU A N   1 
ATOM   2340  C CA  . LEU A 1 307 ? -90.713  -14.696 88.692  1.00 53.47  ? 367 LEU A CA  1 
ATOM   2341  C C   . LEU A 1 307 ? -91.278  -16.100 88.584  1.00 49.66  ? 367 LEU A C   1 
ATOM   2342  O O   . LEU A 1 307 ? -92.352  -16.316 89.093  1.00 53.06  ? 367 LEU A O   1 
ATOM   2343  C CB  . LEU A 1 307 ? -91.473  -13.692 87.829  1.00 49.81  ? 367 LEU A CB  1 
ATOM   2344  C CG  . LEU A 1 307 ? -91.065  -12.235 88.029  1.00 48.19  ? 367 LEU A CG  1 
ATOM   2345  C CD1 . LEU A 1 307 ? -91.978  -11.336 87.230  1.00 52.17  ? 367 LEU A CD1 1 
ATOM   2346  C CD2 . LEU A 1 307 ? -91.104  -11.841 89.486  1.00 47.87  ? 367 LEU A CD2 1 
ATOM   2347  N N   . LYS A 1 308 ? -90.535  -17.030 88.001  1.00 48.87  ? 368 LYS A N   1 
ATOM   2348  C CA  . LYS A 1 308 ? -90.869  -18.470 88.019  1.00 50.98  ? 368 LYS A CA  1 
ATOM   2349  C C   . LYS A 1 308 ? -90.392  -19.068 89.330  1.00 57.27  ? 368 LYS A C   1 
ATOM   2350  O O   . LYS A 1 308 ? -91.077  -19.985 89.800  1.00 67.94  ? 368 LYS A O   1 
ATOM   2351  C CB  . LYS A 1 308 ? -90.275  -19.161 86.797  1.00 57.87  ? 368 LYS A CB  1 
ATOM   2352  C CG  . LYS A 1 308 ? -90.623  -18.371 85.528  1.00 74.68  ? 368 LYS A CG  1 
ATOM   2353  C CD  . LYS A 1 308 ? -90.743  -19.083 84.221  1.00 75.85  ? 368 LYS A CD  1 
ATOM   2354  C CE  . LYS A 1 308 ? -89.408  -19.539 83.690  1.00 85.62  ? 368 LYS A CE  1 
ATOM   2355  N NZ  . LYS A 1 308 ? -89.599  -20.197 82.382  1.00 108.51 ? 368 LYS A NZ  1 
ATOM   2356  N N   . MET A 1 309 ? -89.284  -18.590 89.906  1.00 57.62  ? 369 MET A N   1 
ATOM   2357  C CA  . MET A 1 309 ? -88.785  -19.155 91.186  1.00 61.23  ? 369 MET A CA  1 
ATOM   2358  C C   . MET A 1 309 ? -89.655  -18.633 92.334  1.00 56.30  ? 369 MET A C   1 
ATOM   2359  O O   . MET A 1 309 ? -90.019  -19.450 93.210  1.00 50.61  ? 369 MET A O   1 
ATOM   2360  C CB  . MET A 1 309 ? -87.335  -18.772 91.482  1.00 74.26  ? 369 MET A CB  1 
ATOM   2361  C CG  . MET A 1 309 ? -86.338  -19.037 90.372  1.00 87.76  ? 369 MET A CG  1 
ATOM   2362  S SD  . MET A 1 309 ? -84.624  -19.103 91.101  1.00 94.73  ? 369 MET A SD  1 
ATOM   2363  C CE  . MET A 1 309 ? -83.814  -17.822 90.149  1.00 85.56  ? 369 MET A CE  1 
ATOM   2364  N N   . VAL A 1 310 ? -89.962  -17.325 92.333  1.00 55.48  ? 370 VAL A N   1 
ATOM   2365  C CA  . VAL A 1 310 ? -90.646  -16.616 93.455  1.00 59.45  ? 370 VAL A CA  1 
ATOM   2366  C C   . VAL A 1 310 ? -92.160  -16.451 93.194  1.00 58.95  ? 370 VAL A C   1 
ATOM   2367  O O   . VAL A 1 310 ? -92.899  -16.329 94.189  1.00 57.50  ? 370 VAL A O   1 
ATOM   2368  C CB  . VAL A 1 310 ? -89.969  -15.269 93.779  1.00 57.22  ? 370 VAL A CB  1 
ATOM   2369  C CG1 . VAL A 1 310 ? -88.498  -15.467 94.087  1.00 57.63  ? 370 VAL A CG1 1 
ATOM   2370  C CG2 . VAL A 1 310 ? -90.168  -14.215 92.708  1.00 58.86  ? 370 VAL A CG2 1 
ATOM   2371  N N   . GLY A 1 311 ? -92.606  -16.428 91.934  1.00 56.62  ? 371 GLY A N   1 
ATOM   2372  C CA  . GLY A 1 311 ? -94.011  -16.166 91.553  1.00 60.24  ? 371 GLY A CA  1 
ATOM   2373  C C   . GLY A 1 311 ? -94.276  -14.683 91.272  1.00 67.15  ? 371 GLY A C   1 
ATOM   2374  O O   . GLY A 1 311 ? -93.533  -13.794 91.818  1.00 68.50  ? 371 GLY A O   1 
ATOM   2375  N N   . GLY A 1 312 ? -95.283  -14.418 90.429  1.00 61.24  ? 372 GLY A N   1 
ATOM   2376  C CA  . GLY A 1 312 ? -95.762  -13.067 90.087  1.00 56.50  ? 372 GLY A CA  1 
ATOM   2377  C C   . GLY A 1 312 ? -95.581  -12.742 88.627  1.00 53.20  ? 372 GLY A C   1 
ATOM   2378  O O   . GLY A 1 312 ? -95.054  -13.569 87.888  1.00 62.72  ? 372 GLY A O   1 
ATOM   2379  N N   . THR A 1 313 ? -95.965  -11.534 88.237  1.00 55.10  ? 373 THR A N   1 
ATOM   2380  C CA  . THR A 1 313 ? -95.852  -11.000 86.861  1.00 60.01  ? 373 THR A CA  1 
ATOM   2381  C C   . THR A 1 313 ? -95.003  -9.737  86.900  1.00 51.53  ? 373 THR A C   1 
ATOM   2382  O O   . THR A 1 313 ? -94.800  -9.228  88.002  1.00 44.72  ? 373 THR A O   1 
ATOM   2383  C CB  . THR A 1 313 ? -97.235  -10.689 86.280  1.00 77.45  ? 373 THR A CB  1 
ATOM   2384  O OG1 . THR A 1 313 ? -97.700  -9.473  86.875  1.00 82.12  ? 373 THR A OG1 1 
ATOM   2385  C CG2 . THR A 1 313 ? -98.219  -11.824 86.483  1.00 75.81  ? 373 THR A CG2 1 
ATOM   2386  N N   . LEU A 1 314 ? -94.560  -9.273  85.733  1.00 50.19  ? 374 LEU A N   1 
ATOM   2387  C CA  . LEU A 1 314 ? -93.780  -8.025  85.576  1.00 52.72  ? 374 LEU A CA  1 
ATOM   2388  C C   . LEU A 1 314 ? -94.664  -6.863  86.034  1.00 56.30  ? 374 LEU A C   1 
ATOM   2389  O O   . LEU A 1 314 ? -94.154  -5.952  86.700  1.00 66.70  ? 374 LEU A O   1 
ATOM   2390  C CB  . LEU A 1 314 ? -93.342  -7.838  84.115  1.00 56.32  ? 374 LEU A CB  1 
ATOM   2391  C CG  . LEU A 1 314 ? -92.356  -8.875  83.568  1.00 59.68  ? 374 LEU A CG  1 
ATOM   2392  C CD1 . LEU A 1 314 ? -91.064  -8.876  84.367  1.00 68.27  ? 374 LEU A CD1 1 
ATOM   2393  C CD2 . LEU A 1 314 ? -92.973  -10.268 83.594  1.00 65.97  ? 374 LEU A CD2 1 
ATOM   2394  N N   . ALA A 1 315 ? -95.950  -6.900  85.697  1.00 62.07  ? 375 ALA A N   1 
ATOM   2395  C CA  . ALA A 1 315 ? -96.898  -5.798  85.964  1.00 65.13  ? 375 ALA A CA  1 
ATOM   2396  C C   . ALA A 1 315 ? -96.778  -5.364  87.428  1.00 61.46  ? 375 ALA A C   1 
ATOM   2397  O O   . ALA A 1 315 ? -96.491  -4.164  87.635  1.00 66.38  ? 375 ALA A O   1 
ATOM   2398  C CB  . ALA A 1 315 ? -98.301  -6.209  85.604  1.00 68.04  ? 375 ALA A CB  1 
ATOM   2399  N N   . GLU A 1 316 ? -96.930  -6.305  88.374  1.00 63.86  ? 376 GLU A N   1 
ATOM   2400  C CA  . GLU A 1 316 ? -97.059  -6.019  89.834  1.00 70.54  ? 376 GLU A CA  1 
ATOM   2401  C C   . GLU A 1 316 ? -95.763  -5.462  90.438  1.00 65.23  ? 376 GLU A C   1 
ATOM   2402  O O   . GLU A 1 316 ? -95.885  -4.736  91.455  1.00 73.23  ? 376 GLU A O   1 
ATOM   2403  C CB  . GLU A 1 316 ? -97.344  -7.248  90.699  1.00 84.14  ? 376 GLU A CB  1 
ATOM   2404  C CG  . GLU A 1 316 ? -98.601  -7.995  90.370  1.00 94.33  ? 376 GLU A CG  1 
ATOM   2405  C CD  . GLU A 1 316 ? -98.219  -9.224  89.593  1.00 105.08 ? 376 GLU A CD  1 
ATOM   2406  O OE1 . GLU A 1 316 ? -98.290  -10.331 90.163  1.00 104.51 ? 376 GLU A OE1 1 
ATOM   2407  O OE2 . GLU A 1 316 ? -97.737  -9.046  88.451  1.00 113.37 ? 376 GLU A OE2 1 
ATOM   2408  N N   . GLN A 1 317 ? -94.585  -5.805  89.890  1.00 54.97  ? 377 GLN A N   1 
ATOM   2409  C CA  . GLN A 1 317 ? -93.278  -5.452  90.503  1.00 50.67  ? 377 GLN A CA  1 
ATOM   2410  C C   . GLN A 1 317 ? -93.031  -3.930  90.433  1.00 54.66  ? 377 GLN A C   1 
ATOM   2411  O O   . GLN A 1 317 ? -93.622  -3.214  89.517  1.00 47.07  ? 377 GLN A O   1 
ATOM   2412  C CB  . GLN A 1 317 ? -92.140  -6.168  89.797  1.00 51.99  ? 377 GLN A CB  1 
ATOM   2413  C CG  . GLN A 1 317 ? -92.371  -7.650  89.570  1.00 53.93  ? 377 GLN A CG  1 
ATOM   2414  C CD  . GLN A 1 317 ? -92.541  -8.415  90.852  1.00 52.50  ? 377 GLN A CD  1 
ATOM   2415  O OE1 . GLN A 1 317 ? -91.826  -8.204  91.841  1.00 53.78  ? 377 GLN A OE1 1 
ATOM   2416  N NE2 . GLN A 1 317 ? -93.470  -9.354  90.815  1.00 52.86  ? 377 GLN A NE2 1 
ATOM   2417  N N   . THR A 1 318 ? -92.202  -3.436  91.363  1.00 52.78  ? 378 THR A N   1 
ATOM   2418  C CA  . THR A 1 318 ? -91.679  -2.046  91.347  1.00 61.35  ? 378 THR A CA  1 
ATOM   2419  C C   . THR A 1 318 ? -90.162  -2.105  91.141  1.00 64.96  ? 378 THR A C   1 
ATOM   2420  O O   . THR A 1 318 ? -89.476  -2.787  91.964  1.00 79.19  ? 378 THR A O   1 
ATOM   2421  C CB  . THR A 1 318 ? -92.090  -1.244  92.590  1.00 59.77  ? 378 THR A CB  1 
ATOM   2422  O OG1 . THR A 1 318 ? -93.513  -1.275  92.605  1.00 68.15  ? 378 THR A OG1 1 
ATOM   2423  C CG2 . THR A 1 318 ? -91.678  0.212   92.551  1.00 55.12  ? 378 THR A CG2 1 
ATOM   2424  N N   . TYR A 1 319 ? -89.687  -1.371  90.119  1.00 59.18  ? 379 TYR A N   1 
ATOM   2425  C CA  . TYR A 1 319 ? -88.299  -1.389  89.594  1.00 50.65  ? 379 TYR A CA  1 
ATOM   2426  C C   . TYR A 1 319 ? -87.550  -0.122  89.994  1.00 42.84  ? 379 TYR A C   1 
ATOM   2427  O O   . TYR A 1 319 ? -88.047  0.965   89.718  1.00 32.51  ? 379 TYR A O   1 
ATOM   2428  C CB  . TYR A 1 319 ? -88.333  -1.482  88.067  1.00 58.27  ? 379 TYR A CB  1 
ATOM   2429  C CG  . TYR A 1 319 ? -89.122  -2.653  87.554  1.00 56.99  ? 379 TYR A CG  1 
ATOM   2430  C CD1 . TYR A 1 319 ? -90.456  -2.519  87.244  1.00 53.60  ? 379 TYR A CD1 1 
ATOM   2431  C CD2 . TYR A 1 319 ? -88.544  -3.909  87.450  1.00 59.80  ? 379 TYR A CD2 1 
ATOM   2432  C CE1 . TYR A 1 319 ? -91.198  -3.597  86.803  1.00 55.23  ? 379 TYR A CE1 1 
ATOM   2433  C CE2 . TYR A 1 319 ? -89.274  -5.002  87.024  1.00 59.03  ? 379 TYR A CE2 1 
ATOM   2434  C CZ  . TYR A 1 319 ? -90.606  -4.842  86.700  1.00 54.33  ? 379 TYR A CZ  1 
ATOM   2435  O OH  . TYR A 1 319 ? -91.308  -5.915  86.259  1.00 51.79  ? 379 TYR A OH  1 
ATOM   2436  N N   . LEU A 1 320 ? -86.384  -0.284  90.620  1.00 48.23  ? 380 LEU A N   1 
ATOM   2437  C CA  . LEU A 1 320 ? -85.400  0.797   90.843  1.00 51.24  ? 380 LEU A CA  1 
ATOM   2438  C C   . LEU A 1 320 ? -84.078  0.462   90.140  1.00 57.27  ? 380 LEU A C   1 
ATOM   2439  O O   . LEU A 1 320 ? -83.487  -0.594  90.410  1.00 56.39  ? 380 LEU A O   1 
ATOM   2440  C CB  . LEU A 1 320 ? -85.189  0.992   92.341  1.00 54.00  ? 380 LEU A CB  1 
ATOM   2441  C CG  . LEU A 1 320 ? -84.389  2.236   92.712  1.00 50.91  ? 380 LEU A CG  1 
ATOM   2442  C CD1 . LEU A 1 320 ? -85.000  3.465   92.063  1.00 51.51  ? 380 LEU A CD1 1 
ATOM   2443  C CD2 . LEU A 1 320 ? -84.325  2.395   94.228  1.00 50.89  ? 380 LEU A CD2 1 
ATOM   2444  N N   . PHE A 1 321 ? -83.643  1.380   89.276  1.00 67.71  ? 381 PHE A N   1 
ATOM   2445  C CA  . PHE A 1 321 ? -82.367  1.374   88.509  1.00 66.77  ? 381 PHE A CA  1 
ATOM   2446  C C   . PHE A 1 321 ? -81.375  2.377   89.117  1.00 62.92  ? 381 PHE A C   1 
ATOM   2447  O O   . PHE A 1 321 ? -81.722  3.540   89.394  1.00 55.52  ? 381 PHE A O   1 
ATOM   2448  C CB  . PHE A 1 321 ? -82.602  1.734   87.035  1.00 66.04  ? 381 PHE A CB  1 
ATOM   2449  C CG  . PHE A 1 321 ? -83.347  0.685   86.251  1.00 69.66  ? 381 PHE A CG  1 
ATOM   2450  C CD1 . PHE A 1 321 ? -82.687  -0.421  85.735  1.00 72.86  ? 381 PHE A CD1 1 
ATOM   2451  C CD2 . PHE A 1 321 ? -84.709  0.789   86.029  1.00 70.72  ? 381 PHE A CD2 1 
ATOM   2452  C CE1 . PHE A 1 321 ? -83.375  -1.398  85.028  1.00 74.64  ? 381 PHE A CE1 1 
ATOM   2453  C CE2 . PHE A 1 321 ? -85.397  -0.190  85.318  1.00 69.28  ? 381 PHE A CE2 1 
ATOM   2454  C CZ  . PHE A 1 321 ? -84.736  -1.298  84.842  1.00 70.69  ? 381 PHE A CZ  1 
ATOM   2455  N N   . LEU A 1 322 ? -80.144  1.931   89.324  1.00 61.03  ? 382 LEU A N   1 
ATOM   2456  C CA  . LEU A 1 322 ? -78.993  2.849   89.409  1.00 60.62  ? 382 LEU A CA  1 
ATOM   2457  C C   . LEU A 1 322 ? -78.371  2.906   88.017  1.00 64.19  ? 382 LEU A C   1 
ATOM   2458  O O   . LEU A 1 322 ? -78.045  1.832   87.484  1.00 65.13  ? 382 LEU A O   1 
ATOM   2459  C CB  . LEU A 1 322 ? -77.997  2.365   90.465  1.00 60.23  ? 382 LEU A CB  1 
ATOM   2460  C CG  . LEU A 1 322 ? -76.867  3.356   90.766  1.00 62.04  ? 382 LEU A CG  1 
ATOM   2461  C CD1 . LEU A 1 322 ? -77.373  4.743   91.166  1.00 54.67  ? 382 LEU A CD1 1 
ATOM   2462  C CD2 . LEU A 1 322 ? -75.943  2.788   91.841  1.00 68.79  ? 382 LEU A CD2 1 
ATOM   2463  N N   . GLY A 1 323 ? -78.275  4.110   87.442  1.00 61.08  ? 383 GLY A N   1 
ATOM   2464  C CA  . GLY A 1 323 ? -77.690  4.378   86.116  1.00 57.14  ? 383 GLY A CA  1 
ATOM   2465  C C   . GLY A 1 323 ? -78.772  4.521   85.067  1.00 67.47  ? 383 GLY A C   1 
ATOM   2466  O O   . GLY A 1 323 ? -79.330  3.471   84.668  1.00 72.48  ? 383 GLY A O   1 
ATOM   2467  N N   . ALA A 1 324 ? -79.056  5.759   84.622  1.00 69.49  ? 384 ALA A N   1 
ATOM   2468  C CA  . ALA A 1 324 ? -80.061  6.096   83.580  1.00 63.62  ? 384 ALA A CA  1 
ATOM   2469  C C   . ALA A 1 324 ? -79.334  6.420   82.273  1.00 59.66  ? 384 ALA A C   1 
ATOM   2470  O O   . ALA A 1 324 ? -79.537  7.510   81.717  1.00 54.76  ? 384 ALA A O   1 
ATOM   2471  C CB  . ALA A 1 324 ? -80.925  7.257   84.016  1.00 64.63  ? 384 ALA A CB  1 
ATOM   2472  N N   . GLY A 1 325 ? -78.533  5.477   81.793  1.00 59.93  ? 385 GLY A N   1 
ATOM   2473  C CA  . GLY A 1 325 ? -77.853  5.605   80.501  1.00 64.80  ? 385 GLY A CA  1 
ATOM   2474  C C   . GLY A 1 325 ? -78.569  4.782   79.456  1.00 60.17  ? 385 GLY A C   1 
ATOM   2475  O O   . GLY A 1 325 ? -79.809  4.681   79.521  1.00 49.43  ? 385 GLY A O   1 
ATOM   2476  N N   . GLU A 1 326 ? -77.773  4.221   78.546  1.00 61.33  ? 386 GLU A N   1 
ATOM   2477  C CA  . GLU A 1 326 ? -78.196  3.266   77.500  1.00 66.04  ? 386 GLU A CA  1 
ATOM   2478  C C   . GLU A 1 326 ? -78.934  2.101   78.153  1.00 64.89  ? 386 GLU A C   1 
ATOM   2479  O O   . GLU A 1 326 ? -80.153  1.995   77.973  1.00 73.22  ? 386 GLU A O   1 
ATOM   2480  C CB  . GLU A 1 326 ? -77.000  2.779   76.688  1.00 69.80  ? 386 GLU A CB  1 
ATOM   2481  C CG  . GLU A 1 326 ? -76.237  3.932   76.083  1.00 78.44  ? 386 GLU A CG  1 
ATOM   2482  C CD  . GLU A 1 326 ? -75.043  3.542   75.249  1.00 83.61  ? 386 GLU A CD  1 
ATOM   2483  O OE1 . GLU A 1 326 ? -74.114  4.350   75.267  1.00 83.27  ? 386 GLU A OE1 1 
ATOM   2484  O OE2 . GLU A 1 326 ? -75.079  2.505   74.542  1.00 98.60  ? 386 GLU A OE2 1 
ATOM   2485  N N   . ALA A 1 327 ? -78.224  1.267   78.900  1.00 62.65  ? 387 ALA A N   1 
ATOM   2486  C CA  . ALA A 1 327 ? -78.785  0.017   79.459  1.00 67.00  ? 387 ALA A CA  1 
ATOM   2487  C C   . ALA A 1 327 ? -79.930  0.380   80.409  1.00 63.16  ? 387 ALA A C   1 
ATOM   2488  O O   . ALA A 1 327 ? -80.957  -0.300  80.389  1.00 70.89  ? 387 ALA A O   1 
ATOM   2489  C CB  . ALA A 1 327 ? -77.710  -0.812  80.124  1.00 62.01  ? 387 ALA A CB  1 
ATOM   2490  N N   . GLY A 1 328 ? -79.770  1.432   81.199  1.00 67.13  ? 388 GLY A N   1 
ATOM   2491  C CA  . GLY A 1 328 ? -80.809  1.906   82.129  1.00 65.30  ? 388 GLY A CA  1 
ATOM   2492  C C   . GLY A 1 328 ? -82.139  2.041   81.420  1.00 62.59  ? 388 GLY A C   1 
ATOM   2493  O O   . GLY A 1 328 ? -82.985  1.122   81.587  1.00 63.17  ? 388 GLY A O   1 
ATOM   2494  N N   . THR A 1 329 ? -82.303  3.116   80.632  1.00 56.74  ? 389 THR A N   1 
ATOM   2495  C CA  . THR A 1 329 ? -83.569  3.451   79.931  1.00 53.79  ? 389 THR A CA  1 
ATOM   2496  C C   . THR A 1 329 ? -83.940  2.303   78.987  1.00 51.33  ? 389 THR A C   1 
ATOM   2497  O O   . THR A 1 329 ? -85.107  1.952   78.927  1.00 63.50  ? 389 THR A O   1 
ATOM   2498  C CB  . THR A 1 329 ? -83.483  4.809   79.226  1.00 52.42  ? 389 THR A CB  1 
ATOM   2499  O OG1 . THR A 1 329 ? -82.508  4.729   78.192  1.00 49.85  ? 389 THR A OG1 1 
ATOM   2500  C CG2 . THR A 1 329 ? -83.138  5.934   80.178  1.00 54.86  ? 389 THR A CG2 1 
ATOM   2501  N N   . GLY A 1 330 ? -82.964  1.726   78.303  1.00 56.74  ? 390 GLY A N   1 
ATOM   2502  C CA  . GLY A 1 330 ? -83.154  0.608   77.361  1.00 57.94  ? 390 GLY A CA  1 
ATOM   2503  C C   . GLY A 1 330 ? -83.797  -0.602  78.011  1.00 58.62  ? 390 GLY A C   1 
ATOM   2504  O O   . GLY A 1 330 ? -84.783  -1.083  77.458  1.00 63.03  ? 390 GLY A O   1 
ATOM   2505  N N   . ILE A 1 331 ? -83.269  -1.080  79.139  1.00 56.27  ? 391 ILE A N   1 
ATOM   2506  C CA  . ILE A 1 331 ? -83.856  -2.232  79.877  1.00 62.66  ? 391 ILE A CA  1 
ATOM   2507  C C   . ILE A 1 331 ? -85.282  -1.833  80.281  1.00 59.53  ? 391 ILE A C   1 
ATOM   2508  O O   . ILE A 1 331 ? -86.220  -2.618  80.041  1.00 50.92  ? 391 ILE A O   1 
ATOM   2509  C CB  . ILE A 1 331 ? -82.999  -2.649  81.099  1.00 69.03  ? 391 ILE A CB  1 
ATOM   2510  C CG1 . ILE A 1 331 ? -81.530  -2.877  80.755  1.00 65.29  ? 391 ILE A CG1 1 
ATOM   2511  C CG2 . ILE A 1 331 ? -83.563  -3.895  81.757  1.00 71.54  ? 391 ILE A CG2 1 
ATOM   2512  C CD1 . ILE A 1 331 ? -80.669  -3.029  81.968  1.00 63.58  ? 391 ILE A CD1 1 
ATOM   2513  N N   . ALA A 1 332 ? -85.434  -0.642  80.860  1.00 53.51  ? 392 ALA A N   1 
ATOM   2514  C CA  . ALA A 1 332 ? -86.712  -0.138  81.405  1.00 54.98  ? 392 ALA A CA  1 
ATOM   2515  C C   . ALA A 1 332 ? -87.774  -0.157  80.316  1.00 52.14  ? 392 ALA A C   1 
ATOM   2516  O O   . ALA A 1 332 ? -88.864  -0.670  80.557  1.00 64.30  ? 392 ALA A O   1 
ATOM   2517  C CB  . ALA A 1 332 ? -86.527  1.259   81.938  1.00 65.10  ? 392 ALA A CB  1 
ATOM   2518  N N   . GLU A 1 333 ? -87.457  0.401   79.154  1.00 55.84  ? 393 GLU A N   1 
ATOM   2519  C CA  . GLU A 1 333 ? -88.405  0.514   78.019  1.00 54.96  ? 393 GLU A CA  1 
ATOM   2520  C C   . GLU A 1 333 ? -88.829  -0.881  77.557  1.00 51.93  ? 393 GLU A C   1 
ATOM   2521  O O   . GLU A 1 333 ? -89.980  -1.022  77.215  1.00 57.35  ? 393 GLU A O   1 
ATOM   2522  C CB  . GLU A 1 333 ? -87.778  1.320   76.884  1.00 52.06  ? 393 GLU A CB  1 
ATOM   2523  C CG  . GLU A 1 333 ? -88.746  1.651   75.769  1.00 59.16  ? 393 GLU A CG  1 
ATOM   2524  C CD  . GLU A 1 333 ? -89.947  2.509   76.125  1.00 64.33  ? 393 GLU A CD  1 
ATOM   2525  O OE1 . GLU A 1 333 ? -89.916  3.202   77.154  1.00 83.53  ? 393 GLU A OE1 1 
ATOM   2526  O OE2 . GLU A 1 333 ? -90.927  2.444   75.386  1.00 69.33  ? 393 GLU A OE2 1 
ATOM   2527  N N   . LEU A 1 334 ? -87.934  -1.867  77.548  1.00 51.12  ? 394 LEU A N   1 
ATOM   2528  C CA  . LEU A 1 334 ? -88.275  -3.246  77.112  1.00 54.39  ? 394 LEU A CA  1 
ATOM   2529  C C   . LEU A 1 334 ? -89.156  -3.910  78.174  1.00 53.07  ? 394 LEU A C   1 
ATOM   2530  O O   . LEU A 1 334 ? -89.939  -4.797  77.832  1.00 56.03  ? 394 LEU A O   1 
ATOM   2531  C CB  . LEU A 1 334 ? -87.019  -4.077  76.843  1.00 51.40  ? 394 LEU A CB  1 
ATOM   2532  C CG  . LEU A 1 334 ? -87.290  -5.333  76.014  1.00 52.03  ? 394 LEU A CG  1 
ATOM   2533  C CD1 . LEU A 1 334 ? -87.625  -4.954  74.588  1.00 56.27  ? 394 LEU A CD1 1 
ATOM   2534  C CD2 . LEU A 1 334 ? -86.128  -6.319  76.022  1.00 51.92  ? 394 LEU A CD2 1 
ATOM   2535  N N   . ILE A 1 335 ? -89.037  -3.495  79.420  1.00 62.03  ? 395 ILE A N   1 
ATOM   2536  C CA  . ILE A 1 335 ? -89.869  -4.063  80.521  1.00 66.62  ? 395 ILE A CA  1 
ATOM   2537  C C   . ILE A 1 335 ? -91.301  -3.525  80.365  1.00 65.08  ? 395 ILE A C   1 
ATOM   2538  O O   . ILE A 1 335 ? -92.234  -4.353  80.259  1.00 68.69  ? 395 ILE A O   1 
ATOM   2539  C CB  . ILE A 1 335 ? -89.229  -3.768  81.890  1.00 65.56  ? 395 ILE A CB  1 
ATOM   2540  C CG1 . ILE A 1 335 ? -87.877  -4.478  82.040  1.00 76.79  ? 395 ILE A CG1 1 
ATOM   2541  C CG2 . ILE A 1 335 ? -90.169  -4.156  82.996  1.00 73.12  ? 395 ILE A CG2 1 
ATOM   2542  C CD1 . ILE A 1 335 ? -87.163  -4.242  83.367  1.00 76.17  ? 395 ILE A CD1 1 
ATOM   2543  N N   . ALA A 1 336 ? -91.446  -2.197  80.299  1.00 59.49  ? 396 ALA A N   1 
ATOM   2544  C CA  . ALA A 1 336 ? -92.725  -1.469  80.127  1.00 52.78  ? 396 ALA A CA  1 
ATOM   2545  C C   . ALA A 1 336 ? -93.437  -2.005  78.875  1.00 51.59  ? 396 ALA A C   1 
ATOM   2546  O O   . ALA A 1 336 ? -94.653  -2.234  78.918  1.00 60.35  ? 396 ALA A O   1 
ATOM   2547  C CB  . ALA A 1 336 ? -92.484  0.022   80.046  1.00 48.92  ? 396 ALA A CB  1 
ATOM   2548  N N   . LEU A 1 337 ? -92.705  -2.233  77.795  1.00 55.11  ? 397 LEU A N   1 
ATOM   2549  C CA  . LEU A 1 337 ? -93.281  -2.792  76.545  1.00 63.15  ? 397 LEU A CA  1 
ATOM   2550  C C   . LEU A 1 337 ? -93.843  -4.191  76.834  1.00 62.72  ? 397 LEU A C   1 
ATOM   2551  O O   . LEU A 1 337 ? -95.002  -4.417  76.474  1.00 62.94  ? 397 LEU A O   1 
ATOM   2552  C CB  . LEU A 1 337 ? -92.232  -2.835  75.423  1.00 69.94  ? 397 LEU A CB  1 
ATOM   2553  C CG  . LEU A 1 337 ? -92.804  -3.113  74.016  1.00 67.92  ? 397 LEU A CG  1 
ATOM   2554  C CD1 . LEU A 1 337 ? -93.054  -1.819  73.231  1.00 69.68  ? 397 LEU A CD1 1 
ATOM   2555  C CD2 . LEU A 1 337 ? -91.913  -4.077  73.244  1.00 61.12  ? 397 LEU A CD2 1 
ATOM   2556  N N   . GLU A 1 338 ? -93.084  -5.083  77.476  1.00 58.20  ? 398 GLU A N   1 
ATOM   2557  C CA  . GLU A 1 338 ? -93.546  -6.457  77.756  1.00 54.35  ? 398 GLU A CA  1 
ATOM   2558  C C   . GLU A 1 338 ? -94.834  -6.390  78.574  1.00 62.88  ? 398 GLU A C   1 
ATOM   2559  O O   . GLU A 1 338 ? -95.726  -7.250  78.331  1.00 64.89  ? 398 GLU A O   1 
ATOM   2560  C CB  . GLU A 1 338 ? -92.458  -7.246  78.484  1.00 53.88  ? 398 GLU A CB  1 
ATOM   2561  C CG  . GLU A 1 338 ? -92.818  -8.675  78.801  1.00 53.15  ? 398 GLU A CG  1 
ATOM   2562  C CD  . GLU A 1 338 ? -93.566  -9.363  77.695  1.00 56.85  ? 398 GLU A CD  1 
ATOM   2563  O OE1 . GLU A 1 338 ? -93.207  -9.198  76.525  1.00 65.58  ? 398 GLU A OE1 1 
ATOM   2564  O OE2 . GLU A 1 338 ? -94.571  -9.946  78.012  1.00 78.62  ? 398 GLU A OE2 1 
ATOM   2565  N N   . ILE A 1 339 ? -94.928  -5.416  79.498  1.00 68.60  ? 399 ILE A N   1 
ATOM   2566  C CA  . ILE A 1 339 ? -96.147  -5.156  80.342  1.00 66.06  ? 399 ILE A CA  1 
ATOM   2567  C C   . ILE A 1 339 ? -97.319  -4.757  79.433  1.00 58.59  ? 399 ILE A C   1 
ATOM   2568  O O   . ILE A 1 339 ? -98.367  -5.381  79.527  1.00 51.92  ? 399 ILE A O   1 
ATOM   2569  C CB  . ILE A 1 339 ? -95.873  -4.091  81.428  1.00 64.24  ? 399 ILE A CB  1 
ATOM   2570  C CG1 . ILE A 1 339 ? -94.974  -4.613  82.556  1.00 61.50  ? 399 ILE A CG1 1 
ATOM   2571  C CG2 . ILE A 1 339 ? -97.183  -3.522  81.957  1.00 63.15  ? 399 ILE A CG2 1 
ATOM   2572  C CD1 . ILE A 1 339 ? -94.537  -3.543  83.537  1.00 56.21  ? 399 ILE A CD1 1 
ATOM   2573  N N   . SER A 1 340 ? -97.117  -3.774  78.559  1.00 66.76  ? 400 SER A N   1 
ATOM   2574  C CA  . SER A 1 340 ? -98.130  -3.302  77.575  1.00 73.44  ? 400 SER A CA  1 
ATOM   2575  C C   . SER A 1 340 ? -98.643  -4.483  76.728  1.00 74.75  ? 400 SER A C   1 
ATOM   2576  O O   . SER A 1 340 ? -99.842  -4.500  76.445  1.00 78.68  ? 400 SER A O   1 
ATOM   2577  C CB  . SER A 1 340 ? -97.601  -2.194  76.712  1.00 72.27  ? 400 SER A CB  1 
ATOM   2578  O OG  . SER A 1 340 ? -97.131  -2.709  75.481  1.00 77.99  ? 400 SER A OG  1 
ATOM   2579  N N   . LYS A 1 341 ? -97.797  -5.449  76.363  1.00 75.68  ? 401 LYS A N   1 
ATOM   2580  C CA  . LYS A 1 341 ? -98.205  -6.629  75.555  1.00 78.75  ? 401 LYS A CA  1 
ATOM   2581  C C   . LYS A 1 341 ? -99.017  -7.591  76.440  1.00 73.08  ? 401 LYS A C   1 
ATOM   2582  O O   . LYS A 1 341 ? -99.855  -8.338  75.908  1.00 81.42  ? 401 LYS A O   1 
ATOM   2583  C CB  . LYS A 1 341 ? -96.971  -7.380  75.038  1.00 79.03  ? 401 LYS A CB  1 
ATOM   2584  C CG  . LYS A 1 341 ? -96.485  -7.158  73.602  1.00 86.45  ? 401 LYS A CG  1 
ATOM   2585  C CD  . LYS A 1 341 ? -95.447  -8.249  73.312  1.00 102.50 ? 401 LYS A CD  1 
ATOM   2586  C CE  . LYS A 1 341 ? -95.305  -8.745  71.882  1.00 96.83  ? 401 LYS A CE  1 
ATOM   2587  N NZ  . LYS A 1 341 ? -94.752  -10.123 71.905  1.00 91.72  ? 401 LYS A NZ  1 
ATOM   2588  N N   . GLN A 1 342 ? -98.783  -7.582  77.748  1.00 62.95  ? 402 GLN A N   1 
ATOM   2589  C CA  . GLN A 1 342 ? -99.417  -8.554  78.673  1.00 70.66  ? 402 GLN A CA  1 
ATOM   2590  C C   . GLN A 1 342 ? -100.722 -7.973  79.256  1.00 71.12  ? 402 GLN A C   1 
ATOM   2591  O O   . GLN A 1 342 ? -101.623 -8.742  79.625  1.00 66.41  ? 402 GLN A O   1 
ATOM   2592  C CB  . GLN A 1 342 ? -98.400  -8.909  79.754  1.00 70.51  ? 402 GLN A CB  1 
ATOM   2593  C CG  . GLN A 1 342 ? -98.551  -10.320 80.304  1.00 84.00  ? 402 GLN A CG  1 
ATOM   2594  C CD  . GLN A 1 342 ? -97.208  -10.962 80.565  1.00 81.52  ? 402 GLN A CD  1 
ATOM   2595  O OE1 . GLN A 1 342 ? -96.424  -11.110 79.646  1.00 82.47  ? 402 GLN A OE1 1 
ATOM   2596  N NE2 . GLN A 1 342 ? -96.907  -11.302 81.814  1.00 74.55  ? 402 GLN A NE2 1 
ATOM   2597  N N   . THR A 1 343 ? -100.805 -6.649  79.350  1.00 60.46  ? 403 THR A N   1 
ATOM   2598  C CA  . THR A 1 343 ? -101.828 -5.887  80.085  1.00 58.82  ? 403 THR A CA  1 
ATOM   2599  C C   . THR A 1 343 ? -102.757 -5.172  79.105  1.00 62.25  ? 403 THR A C   1 
ATOM   2600  O O   . THR A 1 343 ? -103.919 -4.971  79.439  1.00 67.53  ? 403 THR A O   1 
ATOM   2601  C CB  . THR A 1 343 ? -101.081 -4.929  81.022  1.00 59.07  ? 403 THR A CB  1 
ATOM   2602  O OG1 . THR A 1 343 ? -101.717 -4.966  82.292  1.00 74.95  ? 403 THR A OG1 1 
ATOM   2603  C CG2 . THR A 1 343 ? -100.977 -3.510  80.524  1.00 61.72  ? 403 THR A CG2 1 
ATOM   2604  N N   . ASN A 1 344 ? -102.233 -4.760  77.962  1.00 71.37  ? 404 ASN A N   1 
ATOM   2605  C CA  . ASN A 1 344 ? -102.940 -3.959  76.928  1.00 70.39  ? 404 ASN A CA  1 
ATOM   2606  C C   . ASN A 1 344 ? -103.121 -2.530  77.449  1.00 61.10  ? 404 ASN A C   1 
ATOM   2607  O O   . ASN A 1 344 ? -103.936 -1.769  76.882  1.00 58.26  ? 404 ASN A O   1 
ATOM   2608  C CB  . ASN A 1 344 ? -104.244 -4.622  76.484  1.00 76.79  ? 404 ASN A CB  1 
ATOM   2609  C CG  . ASN A 1 344 ? -104.775 -4.090  75.168  1.00 85.56  ? 404 ASN A CG  1 
ATOM   2610  O OD1 . ASN A 1 344 ? -105.926 -4.342  74.822  1.00 116.02 ? 404 ASN A OD1 1 
ATOM   2611  N ND2 . ASN A 1 344 ? -103.980 -3.314  74.444  1.00 86.10  ? 404 ASN A ND2 1 
ATOM   2612  N N   . ALA A 1 345 ? -102.317 -2.124  78.420  1.00 53.54  ? 405 ALA A N   1 
ATOM   2613  C CA  . ALA A 1 345 ? -102.398 -0.744  78.929  1.00 66.12  ? 405 ALA A CA  1 
ATOM   2614  C C   . ALA A 1 345 ? -101.635 0.195   77.989  1.00 72.95  ? 405 ALA A C   1 
ATOM   2615  O O   . ALA A 1 345 ? -100.772 -0.244  77.223  1.00 67.46  ? 405 ALA A O   1 
ATOM   2616  C CB  . ALA A 1 345 ? -101.873 -0.693  80.338  1.00 67.78  ? 405 ALA A CB  1 
ATOM   2617  N N   . PRO A 1 346 ? -101.934 1.520   78.020  1.00 80.17  ? 406 PRO A N   1 
ATOM   2618  C CA  . PRO A 1 346 ? -101.051 2.540   77.455  1.00 83.81  ? 406 PRO A CA  1 
ATOM   2619  C C   . PRO A 1 346 ? -99.648  2.477   78.082  1.00 86.72  ? 406 PRO A C   1 
ATOM   2620  O O   . PRO A 1 346 ? -99.526  2.126   79.247  1.00 84.46  ? 406 PRO A O   1 
ATOM   2621  C CB  . PRO A 1 346 ? -101.729 3.892   77.773  1.00 76.43  ? 406 PRO A CB  1 
ATOM   2622  C CG  . PRO A 1 346 ? -102.735 3.571   78.856  1.00 77.49  ? 406 PRO A CG  1 
ATOM   2623  C CD  . PRO A 1 346 ? -103.137 2.128   78.611  1.00 74.50  ? 406 PRO A CD  1 
ATOM   2624  N N   . ILE A 1 347 ? -98.624  2.824   77.302  1.00 87.59  ? 407 ILE A N   1 
ATOM   2625  C CA  . ILE A 1 347 ? -97.219  2.537   77.692  1.00 88.08  ? 407 ILE A CA  1 
ATOM   2626  C C   . ILE A 1 347 ? -96.925  3.316   78.981  1.00 89.06  ? 407 ILE A C   1 
ATOM   2627  O O   . ILE A 1 347 ? -96.408  2.664   79.912  1.00 89.78  ? 407 ILE A O   1 
ATOM   2628  C CB  . ILE A 1 347 ? -96.236  2.785   76.532  1.00 90.75  ? 407 ILE A CB  1 
ATOM   2629  C CG1 . ILE A 1 347 ? -94.960  1.950   76.719  1.00 87.16  ? 407 ILE A CG1 1 
ATOM   2630  C CG2 . ILE A 1 347 ? -95.963  4.271   76.325  1.00 94.37  ? 407 ILE A CG2 1 
ATOM   2631  C CD1 . ILE A 1 347 ? -95.145  0.478   76.504  1.00 84.88  ? 407 ILE A CD1 1 
ATOM   2632  N N   . GLU A 1 348 ? -97.335  4.588   79.114  1.00 83.68  ? 408 GLU A N   1 
ATOM   2633  C CA  . GLU A 1 348 ? -96.979  5.340   80.362  1.00 97.10  ? 408 GLU A CA  1 
ATOM   2634  C C   . GLU A 1 348 ? -97.901  5.022   81.543  1.00 81.15  ? 408 GLU A C   1 
ATOM   2635  O O   . GLU A 1 348 ? -97.833  5.756   82.524  1.00 86.37  ? 408 GLU A O   1 
ATOM   2636  C CB  . GLU A 1 348 ? -96.895  6.864   80.249  1.00 117.89 ? 408 GLU A CB  1 
ATOM   2637  C CG  . GLU A 1 348 ? -95.890  7.440   81.272  1.00 133.57 ? 408 GLU A CG  1 
ATOM   2638  C CD  . GLU A 1 348 ? -96.386  8.337   82.399  1.00 128.02 ? 408 GLU A CD  1 
ATOM   2639  O OE1 . GLU A 1 348 ? -97.426  9.004   82.207  1.00 124.04 ? 408 GLU A OE1 1 
ATOM   2640  O OE2 . GLU A 1 348 ? -95.712  8.361   83.461  1.00 108.17 ? 408 GLU A OE2 1 
ATOM   2641  N N   . GLU A 1 349 ? -98.710  3.963   81.484  1.00 78.40  ? 409 GLU A N   1 
ATOM   2642  C CA  . GLU A 1 349 ? -99.243  3.288   82.705  1.00 79.53  ? 409 GLU A CA  1 
ATOM   2643  C C   . GLU A 1 349 ? -98.315  2.107   83.005  1.00 82.69  ? 409 GLU A C   1 
ATOM   2644  O O   . GLU A 1 349 ? -98.289  1.729   84.188  1.00 89.00  ? 409 GLU A O   1 
ATOM   2645  C CB  . GLU A 1 349 ? -100.771 3.029   82.664  1.00 85.77  ? 409 GLU A CB  1 
ATOM   2646  C CG  . GLU A 1 349 ? -101.289 1.587   82.918  1.00 113.04 ? 409 GLU A CG  1 
ATOM   2647  C CD  . GLU A 1 349 ? -101.322 0.949   84.317  1.00 119.30 ? 409 GLU A CD  1 
ATOM   2648  O OE1 . GLU A 1 349 ? -101.287 -0.325  84.409  1.00 91.60  ? 409 GLU A OE1 1 
ATOM   2649  O OE2 . GLU A 1 349 ? -101.427 1.691   85.322  1.00 141.41 ? 409 GLU A OE2 1 
ATOM   2650  N N   . CYS A 1 350 ? -97.573  1.572   82.024  1.00 74.91  ? 410 CYS A N   1 
ATOM   2651  C CA  . CYS A 1 350 ? -96.660  0.412   82.240  1.00 74.80  ? 410 CYS A CA  1 
ATOM   2652  C C   . CYS A 1 350 ? -95.352  0.864   82.934  1.00 80.54  ? 410 CYS A C   1 
ATOM   2653  O O   . CYS A 1 350 ? -94.705  0.031   83.653  1.00 58.06  ? 410 CYS A O   1 
ATOM   2654  C CB  . CYS A 1 350 ? -96.425  -0.312  80.924  1.00 64.65  ? 410 CYS A CB  1 
ATOM   2655  S SG  . CYS A 1 350 ? -97.967  -0.853  80.157  1.00 48.77  ? 410 CYS A SG  1 
ATOM   2656  N N   . ARG A 1 351 ? -94.992  2.155   82.804  1.00 79.46  ? 411 ARG A N   1 
ATOM   2657  C CA  . ARG A 1 351 ? -93.726  2.670   83.391  1.00 77.11  ? 411 ARG A CA  1 
ATOM   2658  C C   . ARG A 1 351 ? -93.988  3.489   84.645  1.00 66.70  ? 411 ARG A C   1 
ATOM   2659  O O   . ARG A 1 351 ? -93.017  3.971   85.273  1.00 64.60  ? 411 ARG A O   1 
ATOM   2660  C CB  . ARG A 1 351 ? -92.899  3.465   82.389  1.00 82.60  ? 411 ARG A CB  1 
ATOM   2661  C CG  . ARG A 1 351 ? -93.618  4.465   81.507  1.00 82.92  ? 411 ARG A CG  1 
ATOM   2662  C CD  . ARG A 1 351 ? -92.529  5.174   80.694  1.00 84.78  ? 411 ARG A CD  1 
ATOM   2663  N NE  . ARG A 1 351 ? -92.304  4.622   79.360  1.00 81.01  ? 411 ARG A NE  1 
ATOM   2664  C CZ  . ARG A 1 351 ? -92.743  5.165   78.237  1.00 67.92  ? 411 ARG A CZ  1 
ATOM   2665  N NH1 . ARG A 1 351 ? -93.431  6.295   78.250  1.00 66.95  ? 411 ARG A NH1 1 
ATOM   2666  N NH2 . ARG A 1 351 ? -92.507  4.564   77.089  1.00 66.87  ? 411 ARG A NH2 1 
ATOM   2667  N N   . LYS A 1 352 ? -95.233  3.546   85.089  1.00 68.70  ? 412 LYS A N   1 
ATOM   2668  C CA  . LYS A 1 352 ? -95.631  4.214   86.361  1.00 69.57  ? 412 LYS A CA  1 
ATOM   2669  C C   . LYS A 1 352 ? -94.834  3.617   87.536  1.00 56.47  ? 412 LYS A C   1 
ATOM   2670  O O   . LYS A 1 352 ? -94.530  4.370   88.440  1.00 54.66  ? 412 LYS A O   1 
ATOM   2671  C CB  . LYS A 1 352 ? -97.162  4.142   86.526  1.00 75.93  ? 412 LYS A CB  1 
ATOM   2672  C CG  . LYS A 1 352 ? -97.692  3.377   87.736  1.00 84.23  ? 412 LYS A CG  1 
ATOM   2673  C CD  . LYS A 1 352 ? -99.190  3.202   87.808  1.00 83.13  ? 412 LYS A CD  1 
ATOM   2674  C CE  . LYS A 1 352 ? -99.623  2.436   89.045  1.00 91.30  ? 412 LYS A CE  1 
ATOM   2675  N NZ  . LYS A 1 352 ? -101.057 2.050   88.984  1.00 89.25  ? 412 LYS A NZ  1 
ATOM   2676  N N   . LYS A 1 353 ? -94.515  2.320   87.523  1.00 59.12  ? 413 LYS A N   1 
ATOM   2677  C CA  . LYS A 1 353 ? -93.854  1.608   88.657  1.00 66.49  ? 413 LYS A CA  1 
ATOM   2678  C C   . LYS A 1 353 ? -92.355  1.338   88.379  1.00 64.60  ? 413 LYS A C   1 
ATOM   2679  O O   . LYS A 1 353 ? -91.742  0.470   89.069  1.00 60.36  ? 413 LYS A O   1 
ATOM   2680  C CB  . LYS A 1 353 ? -94.669  0.349   88.973  1.00 67.87  ? 413 LYS A CB  1 
ATOM   2681  C CG  . LYS A 1 353 ? -96.091  0.643   89.452  1.00 63.82  ? 413 LYS A CG  1 
ATOM   2682  C CD  . LYS A 1 353 ? -96.530  -0.057  90.741  1.00 72.04  ? 413 LYS A CD  1 
ATOM   2683  C CE  . LYS A 1 353 ? -96.589  -1.570  90.620  1.00 82.44  ? 413 LYS A CE  1 
ATOM   2684  N NZ  . LYS A 1 353 ? -97.606  -1.994  89.624  1.00 82.72  ? 413 LYS A NZ  1 
ATOM   2685  N N   . VAL A 1 354 ? -91.748  2.094   87.461  1.00 65.17  ? 414 VAL A N   1 
ATOM   2686  C CA  . VAL A 1 354 ? -90.312  1.980   87.071  1.00 66.72  ? 414 VAL A CA  1 
ATOM   2687  C C   . VAL A 1 354 ? -89.626  3.323   87.333  1.00 60.98  ? 414 VAL A C   1 
ATOM   2688  O O   . VAL A 1 354 ? -90.018  4.337   86.685  1.00 47.06  ? 414 VAL A O   1 
ATOM   2689  C CB  . VAL A 1 354 ? -90.168  1.558   85.600  1.00 77.42  ? 414 VAL A CB  1 
ATOM   2690  C CG1 . VAL A 1 354 ? -88.709  1.492   85.145  1.00 71.24  ? 414 VAL A CG1 1 
ATOM   2691  C CG2 . VAL A 1 354 ? -90.902  0.248   85.329  1.00 85.18  ? 414 VAL A CG2 1 
ATOM   2692  N N   . TRP A 1 355 ? -88.631  3.305   88.233  1.00 52.32  ? 415 TRP A N   1 
ATOM   2693  C CA  . TRP A 1 355 ? -87.891  4.484   88.737  1.00 57.67  ? 415 TRP A CA  1 
ATOM   2694  C C   . TRP A 1 355 ? -86.397  4.319   88.496  1.00 65.67  ? 415 TRP A C   1 
ATOM   2695  O O   . TRP A 1 355 ? -85.864  3.291   88.918  1.00 63.91  ? 415 TRP A O   1 
ATOM   2696  C CB  . TRP A 1 355 ? -88.144  4.630   90.227  1.00 58.56  ? 415 TRP A CB  1 
ATOM   2697  C CG  . TRP A 1 355 ? -89.583  4.727   90.611  1.00 57.03  ? 415 TRP A CG  1 
ATOM   2698  C CD1 . TRP A 1 355 ? -90.454  3.697   90.833  1.00 57.86  ? 415 TRP A CD1 1 
ATOM   2699  C CD2 . TRP A 1 355 ? -90.309  5.946   90.849  1.00 56.15  ? 415 TRP A CD2 1 
ATOM   2700  N NE1 . TRP A 1 355 ? -91.678  4.187   91.201  1.00 55.92  ? 415 TRP A NE1 1 
ATOM   2701  C CE2 . TRP A 1 355 ? -91.621  5.566   91.199  1.00 57.80  ? 415 TRP A CE2 1 
ATOM   2702  C CE3 . TRP A 1 355 ? -89.987  7.304   90.763  1.00 52.12  ? 415 TRP A CE3 1 
ATOM   2703  C CZ2 . TRP A 1 355 ? -92.581  6.514   91.543  1.00 53.71  ? 415 TRP A CZ2 1 
ATOM   2704  C CZ3 . TRP A 1 355 ? -90.953  8.229   91.058  1.00 57.53  ? 415 TRP A CZ3 1 
ATOM   2705  C CH2 . TRP A 1 355 ? -92.226  7.837   91.461  1.00 54.43  ? 415 TRP A CH2 1 
ATOM   2706  N N   . LEU A 1 356 ? -85.751  5.325   87.900  1.00 70.55  ? 416 LEU A N   1 
ATOM   2707  C CA  . LEU A 1 356 ? -84.285  5.314   87.659  1.00 63.55  ? 416 LEU A CA  1 
ATOM   2708  C C   . LEU A 1 356 ? -83.619  6.429   88.458  1.00 59.21  ? 416 LEU A C   1 
ATOM   2709  O O   . LEU A 1 356 ? -84.230  7.484   88.588  1.00 55.04  ? 416 LEU A O   1 
ATOM   2710  C CB  . LEU A 1 356 ? -84.015  5.456   86.166  1.00 66.86  ? 416 LEU A CB  1 
ATOM   2711  C CG  . LEU A 1 356 ? -84.448  4.257   85.337  1.00 68.90  ? 416 LEU A CG  1 
ATOM   2712  C CD1 . LEU A 1 356 ? -85.856  4.458   84.829  1.00 75.36  ? 416 LEU A CD1 1 
ATOM   2713  C CD2 . LEU A 1 356 ? -83.477  4.037   84.195  1.00 75.40  ? 416 LEU A CD2 1 
ATOM   2714  N N   . VAL A 1 357 ? -82.436  6.131   89.000  1.00 54.41  ? 417 VAL A N   1 
ATOM   2715  C CA  . VAL A 1 357 ? -81.565  7.060   89.765  1.00 55.00  ? 417 VAL A CA  1 
ATOM   2716  C C   . VAL A 1 357 ? -80.245  7.224   88.999  1.00 65.00  ? 417 VAL A C   1 
ATOM   2717  O O   . VAL A 1 357 ? -79.508  6.220   88.809  1.00 65.92  ? 417 VAL A O   1 
ATOM   2718  C CB  . VAL A 1 357 ? -81.312  6.549   91.191  1.00 54.68  ? 417 VAL A CB  1 
ATOM   2719  C CG1 . VAL A 1 357 ? -80.446  7.519   91.983  1.00 56.87  ? 417 VAL A CG1 1 
ATOM   2720  C CG2 . VAL A 1 357 ? -82.595  6.228   91.930  1.00 50.63  ? 417 VAL A CG2 1 
ATOM   2721  N N   . ASP A 1 358 ? -79.956  8.458   88.604  1.00 62.75  ? 418 ASP A N   1 
ATOM   2722  C CA  . ASP A 1 358 ? -78.696  8.844   87.928  1.00 71.62  ? 418 ASP A CA  1 
ATOM   2723  C C   . ASP A 1 358 ? -77.741  9.499   88.945  1.00 71.61  ? 418 ASP A C   1 
ATOM   2724  O O   . ASP A 1 358 ? -78.018  9.443   90.164  1.00 59.15  ? 418 ASP A O   1 
ATOM   2725  C CB  . ASP A 1 358 ? -79.010  9.765   86.749  1.00 66.73  ? 418 ASP A CB  1 
ATOM   2726  C CG  . ASP A 1 358 ? -79.550  11.111  87.178  1.00 64.05  ? 418 ASP A CG  1 
ATOM   2727  O OD1 . ASP A 1 358 ? -79.324  11.498  88.349  1.00 58.76  ? 418 ASP A OD1 1 
ATOM   2728  O OD2 . ASP A 1 358 ? -80.154  11.775  86.316  1.00 55.71  ? 418 ASP A OD2 1 
ATOM   2729  N N   . SER A 1 359 ? -76.664  10.099  88.427  1.00 75.41  ? 419 SER A N   1 
ATOM   2730  C CA  . SER A 1 359 ? -75.632  10.892  89.146  1.00 70.49  ? 419 SER A CA  1 
ATOM   2731  C C   . SER A 1 359 ? -76.273  11.970  90.030  1.00 62.63  ? 419 SER A C   1 
ATOM   2732  O O   . SER A 1 359 ? -75.795  12.152  91.156  1.00 62.93  ? 419 SER A O   1 
ATOM   2733  C CB  . SER A 1 359 ? -74.634  11.489  88.156  1.00 77.45  ? 419 SER A CB  1 
ATOM   2734  O OG  . SER A 1 359 ? -75.108  11.437  86.802  1.00 73.98  ? 419 SER A OG  1 
ATOM   2735  N N   . LYS A 1 360 ? -77.320  12.649  89.548  1.00 60.78  ? 420 LYS A N   1 
ATOM   2736  C CA  . LYS A 1 360 ? -77.945  13.815  90.237  1.00 68.16  ? 420 LYS A CA  1 
ATOM   2737  C C   . LYS A 1 360 ? -79.060  13.340  91.183  1.00 65.61  ? 420 LYS A C   1 
ATOM   2738  O O   . LYS A 1 360 ? -79.616  14.194  91.901  1.00 65.50  ? 420 LYS A O   1 
ATOM   2739  C CB  . LYS A 1 360 ? -78.454  14.833  89.210  1.00 70.72  ? 420 LYS A CB  1 
ATOM   2740  C CG  . LYS A 1 360 ? -79.062  16.120  89.767  1.00 79.03  ? 420 LYS A CG  1 
ATOM   2741  C CD  . LYS A 1 360 ? -78.230  16.901  90.785  1.00 83.53  ? 420 LYS A CD  1 
ATOM   2742  C CE  . LYS A 1 360 ? -78.835  18.240  91.187  1.00 83.47  ? 420 LYS A CE  1 
ATOM   2743  N NZ  . LYS A 1 360 ? -80.319  18.271  91.068  1.00 77.85  ? 420 LYS A NZ  1 
ATOM   2744  N N   . GLY A 1 361 ? -79.388  12.043  91.182  1.00 69.54  ? 421 GLY A N   1 
ATOM   2745  C CA  . GLY A 1 361 ? -80.357  11.409  92.107  1.00 63.40  ? 421 GLY A CA  1 
ATOM   2746  C C   . GLY A 1 361 ? -81.532  10.761  91.386  1.00 62.72  ? 421 GLY A C   1 
ATOM   2747  O O   . GLY A 1 361 ? -81.389  10.388  90.195  1.00 60.48  ? 421 GLY A O   1 
ATOM   2748  N N   . LEU A 1 362 ? -82.668  10.620  92.079  1.00 63.99  ? 422 LEU A N   1 
ATOM   2749  C CA  . LEU A 1 362 ? -83.910  10.028  91.519  1.00 59.87  ? 422 LEU A CA  1 
ATOM   2750  C C   . LEU A 1 362 ? -84.434  10.957  90.430  1.00 57.27  ? 422 LEU A C   1 
ATOM   2751  O O   . LEU A 1 362 ? -84.537  12.174  90.670  1.00 53.62  ? 422 LEU A O   1 
ATOM   2752  C CB  . LEU A 1 362 ? -84.949  9.827   92.625  1.00 63.29  ? 422 LEU A CB  1 
ATOM   2753  C CG  . LEU A 1 362 ? -86.279  9.190   92.194  1.00 61.21  ? 422 LEU A CG  1 
ATOM   2754  C CD1 . LEU A 1 362 ? -86.066  7.793   91.643  1.00 63.65  ? 422 LEU A CD1 1 
ATOM   2755  C CD2 . LEU A 1 362 ? -87.272  9.111   93.348  1.00 58.83  ? 422 LEU A CD2 1 
ATOM   2756  N N   . ILE A 1 363 ? -84.713  10.385  89.268  1.00 63.60  ? 423 ILE A N   1 
ATOM   2757  C CA  . ILE A 1 363 ? -85.339  11.090  88.115  1.00 75.94  ? 423 ILE A CA  1 
ATOM   2758  C C   . ILE A 1 363 ? -86.808  11.354  88.485  1.00 79.19  ? 423 ILE A C   1 
ATOM   2759  O O   . ILE A 1 363 ? -87.606  10.391  88.642  1.00 84.30  ? 423 ILE A O   1 
ATOM   2760  C CB  . ILE A 1 363 ? -85.222  10.283  86.800  1.00 79.38  ? 423 ILE A CB  1 
ATOM   2761  C CG1 . ILE A 1 363 ? -83.803  9.793   86.487  1.00 65.68  ? 423 ILE A CG1 1 
ATOM   2762  C CG2 . ILE A 1 363 ? -85.848  11.084  85.669  1.00 82.63  ? 423 ILE A CG2 1 
ATOM   2763  C CD1 . ILE A 1 363 ? -83.132  10.523  85.384  1.00 66.79  ? 423 ILE A CD1 1 
ATOM   2764  N N   . VAL A 1 364 ? -87.124  12.638  88.646  1.00 73.89  ? 424 VAL A N   1 
ATOM   2765  C CA  . VAL A 1 364 ? -88.402  13.178  89.161  1.00 66.47  ? 424 VAL A CA  1 
ATOM   2766  C C   . VAL A 1 364 ? -88.861  14.262  88.182  1.00 71.78  ? 424 VAL A C   1 
ATOM   2767  O O   . VAL A 1 364 ? -88.011  14.884  87.538  1.00 63.77  ? 424 VAL A O   1 
ATOM   2768  C CB  . VAL A 1 364 ? -88.131  13.704  90.578  1.00 68.45  ? 424 VAL A CB  1 
ATOM   2769  C CG1 . VAL A 1 364 ? -89.132  14.731  91.073  1.00 81.64  ? 424 VAL A CG1 1 
ATOM   2770  C CG2 . VAL A 1 364 ? -88.032  12.537  91.537  1.00 71.42  ? 424 VAL A CG2 1 
ATOM   2771  N N   . ASP A 1 365 ? -90.171  14.455  88.094  1.00 85.04  ? 425 ASP A N   1 
ATOM   2772  C CA  . ASP A 1 365 ? -90.861  15.465  87.257  1.00 89.12  ? 425 ASP A CA  1 
ATOM   2773  C C   . ASP A 1 365 ? -90.417  16.891  87.612  1.00 86.54  ? 425 ASP A C   1 
ATOM   2774  O O   . ASP A 1 365 ? -90.202  17.710  86.672  1.00 71.96  ? 425 ASP A O   1 
ATOM   2775  C CB  . ASP A 1 365 ? -92.372  15.368  87.473  1.00 97.52  ? 425 ASP A CB  1 
ATOM   2776  C CG  . ASP A 1 365 ? -93.167  15.681  86.224  1.00 120.31 ? 425 ASP A CG  1 
ATOM   2777  O OD1 . ASP A 1 365 ? -92.872  16.714  85.567  1.00 128.14 ? 425 ASP A OD1 1 
ATOM   2778  O OD2 . ASP A 1 365 ? -94.091  14.890  85.904  1.00 145.25 ? 425 ASP A OD2 1 
ATOM   2779  N N   . SER A 1 366 ? -90.234  17.189  88.903  1.00 88.05  ? 426 SER A N   1 
ATOM   2780  C CA  . SER A 1 366 ? -89.808  18.537  89.385  1.00 83.39  ? 426 SER A CA  1 
ATOM   2781  C C   . SER A 1 366 ? -88.468  18.929  88.744  1.00 78.02  ? 426 SER A C   1 
ATOM   2782  O O   . SER A 1 366 ? -88.127  20.114  88.739  1.00 80.04  ? 426 SER A O   1 
ATOM   2783  C CB  . SER A 1 366 ? -89.722  18.586  90.883  1.00 86.99  ? 426 SER A CB  1 
ATOM   2784  O OG  . SER A 1 366 ? -88.749  17.665  91.353  1.00 95.72  ? 426 SER A OG  1 
ATOM   2785  N N   . ARG A 1 367 ? -87.738  17.948  88.220  1.00 80.47  ? 427 ARG A N   1 
ATOM   2786  C CA  . ARG A 1 367 ? -86.364  18.098  87.682  1.00 84.47  ? 427 ARG A CA  1 
ATOM   2787  C C   . ARG A 1 367 ? -86.378  18.073  86.156  1.00 93.37  ? 427 ARG A C   1 
ATOM   2788  O O   . ARG A 1 367 ? -85.311  18.234  85.584  1.00 133.64 ? 427 ARG A O   1 
ATOM   2789  C CB  . ARG A 1 367 ? -85.480  16.955  88.200  1.00 82.17  ? 427 ARG A CB  1 
ATOM   2790  C CG  . ARG A 1 367 ? -84.084  17.389  88.620  1.00 81.79  ? 427 ARG A CG  1 
ATOM   2791  C CD  . ARG A 1 367 ? -83.368  16.191  89.182  1.00 76.37  ? 427 ARG A CD  1 
ATOM   2792  N NE  . ARG A 1 367 ? -82.685  15.481  88.113  1.00 79.56  ? 427 ARG A NE  1 
ATOM   2793  C CZ  . ARG A 1 367 ? -82.303  14.203  88.162  1.00 72.12  ? 427 ARG A CZ  1 
ATOM   2794  N NH1 . ARG A 1 367 ? -82.619  13.440  89.196  1.00 76.81  ? 427 ARG A NH1 1 
ATOM   2795  N NH2 . ARG A 1 367 ? -81.665  13.689  87.133  1.00 63.48  ? 427 ARG A NH2 1 
ATOM   2796  N N   . LYS A 1 368 ? -87.537  17.892  85.517  1.00 106.46 ? 428 LYS A N   1 
ATOM   2797  C CA  . LYS A 1 368 ? -87.683  17.708  84.039  1.00 99.20  ? 428 LYS A CA  1 
ATOM   2798  C C   . LYS A 1 368 ? -87.518  19.065  83.326  1.00 113.94 ? 428 LYS A C   1 
ATOM   2799  O O   . LYS A 1 368 ? -87.226  19.032  82.118  1.00 113.96 ? 428 LYS A O   1 
ATOM   2800  C CB  . LYS A 1 368 ? -89.007  16.987  83.775  1.00 90.24  ? 428 LYS A CB  1 
ATOM   2801  C CG  . LYS A 1 368 ? -89.617  17.062  82.384  1.00 94.26  ? 428 LYS A CG  1 
ATOM   2802  C CD  . LYS A 1 368 ? -91.068  16.615  82.379  1.00 93.44  ? 428 LYS A CD  1 
ATOM   2803  C CE  . LYS A 1 368 ? -91.242  15.120  82.564  1.00 85.01  ? 428 LYS A CE  1 
ATOM   2804  N NZ  . LYS A 1 368 ? -92.611  14.757  82.996  1.00 82.96  ? 428 LYS A NZ  1 
ATOM   2805  N N   . GLY A 1 369 ? -87.649  20.193  84.051  1.00 122.19 ? 429 GLY A N   1 
ATOM   2806  C CA  . GLY A 1 369 ? -87.355  21.559  83.566  1.00 117.05 ? 429 GLY A CA  1 
ATOM   2807  C C   . GLY A 1 369 ? -85.869  21.796  83.310  1.00 119.55 ? 429 GLY A C   1 
ATOM   2808  O O   . GLY A 1 369 ? -85.488  22.993  83.242  1.00 115.55 ? 429 GLY A O   1 
ATOM   2809  N N   . SER A 1 370 ? -85.045  20.732  83.256  1.00 111.30 ? 430 SER A N   1 
ATOM   2810  C CA  . SER A 1 370 ? -83.607  20.723  82.889  1.00 106.73 ? 430 SER A CA  1 
ATOM   2811  C C   . SER A 1 370 ? -83.073  19.279  82.773  1.00 91.97  ? 430 SER A C   1 
ATOM   2812  O O   . SER A 1 370 ? -81.995  18.999  83.340  1.00 89.33  ? 430 SER A O   1 
ATOM   2813  C CB  . SER A 1 370 ? -82.808  21.533  83.911  1.00 110.71 ? 430 SER A CB  1 
ATOM   2814  O OG  . SER A 1 370 ? -83.443  22.771  84.219  1.00 119.95 ? 430 SER A OG  1 
ATOM   2815  N N   . LEU A 1 371 ? -83.801  18.372  82.113  1.00 89.42  ? 431 LEU A N   1 
ATOM   2816  C CA  . LEU A 1 371 ? -83.440  16.927  82.003  1.00 92.26  ? 431 LEU A CA  1 
ATOM   2817  C C   . LEU A 1 371 ? -82.908  16.632  80.597  1.00 90.27  ? 431 LEU A C   1 
ATOM   2818  O O   . LEU A 1 371 ? -83.160  17.433  79.704  1.00 101.25 ? 431 LEU A O   1 
ATOM   2819  C CB  . LEU A 1 371 ? -84.686  16.088  82.321  1.00 89.87  ? 431 LEU A CB  1 
ATOM   2820  C CG  . LEU A 1 371 ? -84.498  15.063  83.439  1.00 75.83  ? 431 LEU A CG  1 
ATOM   2821  C CD1 . LEU A 1 371 ? -85.820  14.489  83.913  1.00 77.70  ? 431 LEU A CD1 1 
ATOM   2822  C CD2 . LEU A 1 371 ? -83.607  13.974  82.922  1.00 75.05  ? 431 LEU A CD2 1 
ATOM   2823  N N   . GLN A 1 372 ? -82.236  15.493  80.429  1.00 91.04  ? 432 GLN A N   1 
ATOM   2824  C CA  . GLN A 1 372 ? -81.824  14.927  79.117  1.00 99.34  ? 432 GLN A CA  1 
ATOM   2825  C C   . GLN A 1 372 ? -83.083  14.322  78.486  1.00 99.91  ? 432 GLN A C   1 
ATOM   2826  O O   . GLN A 1 372 ? -83.966  13.873  79.213  1.00 97.57  ? 432 GLN A O   1 
ATOM   2827  C CB  . GLN A 1 372 ? -80.657  13.939  79.326  1.00 108.37 ? 432 GLN A CB  1 
ATOM   2828  C CG  . GLN A 1 372 ? -79.338  14.560  79.815  1.00 110.60 ? 432 GLN A CG  1 
ATOM   2829  C CD  . GLN A 1 372 ? -79.079  14.600  81.316  1.00 104.48 ? 432 GLN A CD  1 
ATOM   2830  O OE1 . GLN A 1 372 ? -79.979  14.520  82.157  1.00 78.14  ? 432 GLN A OE1 1 
ATOM   2831  N NE2 . GLN A 1 372 ? -77.820  14.801  81.680  1.00 89.71  ? 432 GLN A NE2 1 
ATOM   2832  N N   . PRO A 1 373 ? -83.254  14.317  77.141  1.00 104.36 ? 433 PRO A N   1 
ATOM   2833  C CA  . PRO A 1 373 ? -84.532  13.933  76.528  1.00 99.53  ? 433 PRO A CA  1 
ATOM   2834  C C   . PRO A 1 373 ? -85.005  12.497  76.828  1.00 87.69  ? 433 PRO A C   1 
ATOM   2835  O O   . PRO A 1 373 ? -86.140  12.332  77.143  1.00 76.90  ? 433 PRO A O   1 
ATOM   2836  C CB  . PRO A 1 373 ? -84.284  14.085  75.015  1.00 108.35 ? 433 PRO A CB  1 
ATOM   2837  C CG  . PRO A 1 373 ? -83.067  14.994  74.908  1.00 112.76 ? 433 PRO A CG  1 
ATOM   2838  C CD  . PRO A 1 373 ? -82.237  14.660  76.129  1.00 111.68 ? 433 PRO A CD  1 
ATOM   2839  N N   . PHE A 1 374 ? -84.124  11.501  76.744  1.00 84.93  ? 434 PHE A N   1 
ATOM   2840  C CA  . PHE A 1 374 ? -84.443  10.051  76.855  1.00 84.08  ? 434 PHE A CA  1 
ATOM   2841  C C   . PHE A 1 374 ? -84.741  9.616   78.296  1.00 77.70  ? 434 PHE A C   1 
ATOM   2842  O O   . PHE A 1 374 ? -84.899  8.390   78.507  1.00 67.29  ? 434 PHE A O   1 
ATOM   2843  C CB  . PHE A 1 374 ? -83.279  9.202   76.345  1.00 100.09 ? 434 PHE A CB  1 
ATOM   2844  C CG  . PHE A 1 374 ? -82.008  9.247   77.162  1.00 103.95 ? 434 PHE A CG  1 
ATOM   2845  C CD1 . PHE A 1 374 ? -81.093  10.287  77.010  1.00 92.55  ? 434 PHE A CD1 1 
ATOM   2846  C CD2 . PHE A 1 374 ? -81.691  8.207   78.026  1.00 97.08  ? 434 PHE A CD2 1 
ATOM   2847  C CE1 . PHE A 1 374 ? -79.904  10.294  77.720  1.00 87.17  ? 434 PHE A CE1 1 
ATOM   2848  C CE2 . PHE A 1 374 ? -80.495  8.209   78.730  1.00 103.82 ? 434 PHE A CE2 1 
ATOM   2849  C CZ  . PHE A 1 374 ? -79.602  9.250   78.570  1.00 101.09 ? 434 PHE A CZ  1 
ATOM   2850  N N   . LYS A 1 375 ? -84.766  10.570  79.234  1.00 73.37  ? 435 LYS A N   1 
ATOM   2851  C CA  . LYS A 1 375 ? -85.041  10.353  80.678  1.00 77.50  ? 435 LYS A CA  1 
ATOM   2852  C C   . LYS A 1 375 ? -86.455  10.855  81.031  1.00 86.98  ? 435 LYS A C   1 
ATOM   2853  O O   . LYS A 1 375 ? -87.040  10.334  82.023  1.00 79.27  ? 435 LYS A O   1 
ATOM   2854  C CB  . LYS A 1 375 ? -83.993  11.072  81.531  1.00 72.93  ? 435 LYS A CB  1 
ATOM   2855  C CG  . LYS A 1 375 ? -82.604  10.450  81.518  1.00 69.84  ? 435 LYS A CG  1 
ATOM   2856  C CD  . LYS A 1 375 ? -81.610  11.177  82.410  1.00 65.55  ? 435 LYS A CD  1 
ATOM   2857  C CE  . LYS A 1 375 ? -80.210  10.626  82.316  1.00 70.44  ? 435 LYS A CE  1 
ATOM   2858  N NZ  . LYS A 1 375 ? -79.274  11.392  83.165  1.00 79.17  ? 435 LYS A NZ  1 
ATOM   2859  N N   . LYS A 1 376 ? -87.009  11.801  80.258  1.00 90.47  ? 436 LYS A N   1 
ATOM   2860  C CA  . LYS A 1 376 ? -88.318  12.468  80.518  1.00 83.88  ? 436 LYS A CA  1 
ATOM   2861  C C   . LYS A 1 376 ? -89.424  11.429  80.728  1.00 76.21  ? 436 LYS A C   1 
ATOM   2862  O O   . LYS A 1 376 ? -90.241  11.589  81.636  1.00 85.07  ? 436 LYS A O   1 
ATOM   2863  C CB  . LYS A 1 376 ? -88.670  13.437  79.391  1.00 85.80  ? 436 LYS A CB  1 
ATOM   2864  C CG  . LYS A 1 376 ? -87.977  14.801  79.430  1.00 95.33  ? 436 LYS A CG  1 
ATOM   2865  C CD  . LYS A 1 376 ? -88.790  15.889  78.728  1.00 116.17 ? 436 LYS A CD  1 
ATOM   2866  C CE  . LYS A 1 376 ? -88.033  16.838  77.810  1.00 114.88 ? 436 LYS A CE  1 
ATOM   2867  N NZ  . LYS A 1 376 ? -88.938  17.311  76.733  1.00 122.14 ? 436 LYS A NZ  1 
ATOM   2868  N N   . PRO A 1 377 ? -89.499  10.335  79.935  1.00 68.45  ? 437 PRO A N   1 
ATOM   2869  C CA  . PRO A 1 377 ? -90.512  9.302   80.164  1.00 66.39  ? 437 PRO A CA  1 
ATOM   2870  C C   . PRO A 1 377 ? -90.447  8.582   81.515  1.00 63.09  ? 437 PRO A C   1 
ATOM   2871  O O   . PRO A 1 377 ? -91.352  7.818   81.804  1.00 70.88  ? 437 PRO A O   1 
ATOM   2872  C CB  . PRO A 1 377 ? -90.287  8.233   79.077  1.00 66.47  ? 437 PRO A CB  1 
ATOM   2873  C CG  . PRO A 1 377 ? -89.001  8.633   78.376  1.00 67.21  ? 437 PRO A CG  1 
ATOM   2874  C CD  . PRO A 1 377 ? -88.704  10.077  78.726  1.00 67.17  ? 437 PRO A CD  1 
ATOM   2875  N N   . TRP A 1 378 ? -89.390  8.791   82.293  1.00 56.47  ? 438 TRP A N   1 
ATOM   2876  C CA  . TRP A 1 378 ? -89.231  8.107   83.599  1.00 58.07  ? 438 TRP A CA  1 
ATOM   2877  C C   . TRP A 1 378 ? -89.379  9.105   84.754  1.00 54.55  ? 438 TRP A C   1 
ATOM   2878  O O   . TRP A 1 378 ? -89.388  8.649   85.927  1.00 56.92  ? 438 TRP A O   1 
ATOM   2879  C CB  . TRP A 1 378 ? -87.902  7.356   83.571  1.00 58.80  ? 438 TRP A CB  1 
ATOM   2880  C CG  . TRP A 1 378 ? -87.773  6.527   82.331  1.00 59.22  ? 438 TRP A CG  1 
ATOM   2881  C CD1 . TRP A 1 378 ? -87.055  6.833   81.216  1.00 58.31  ? 438 TRP A CD1 1 
ATOM   2882  C CD2 . TRP A 1 378 ? -88.416  5.275   82.047  1.00 58.74  ? 438 TRP A CD2 1 
ATOM   2883  N NE1 . TRP A 1 378 ? -87.171  5.853   80.276  1.00 56.18  ? 438 TRP A NE1 1 
ATOM   2884  C CE2 . TRP A 1 378 ? -87.993  4.871   80.755  1.00 58.05  ? 438 TRP A CE2 1 
ATOM   2885  C CE3 . TRP A 1 378 ? -89.252  4.430   82.773  1.00 53.29  ? 438 TRP A CE3 1 
ATOM   2886  C CZ2 . TRP A 1 378 ? -88.396  3.669   80.165  1.00 50.26  ? 438 TRP A CZ2 1 
ATOM   2887  C CZ3 . TRP A 1 378 ? -89.674  3.252   82.180  1.00 56.80  ? 438 TRP A CZ3 1 
ATOM   2888  C CH2 . TRP A 1 378 ? -89.255  2.879   80.893  1.00 55.54  ? 438 TRP A CH2 1 
ATOM   2889  N N   . ALA A 1 379 ? -89.548  10.392  84.418  1.00 51.24  ? 439 ALA A N   1 
ATOM   2890  C CA  . ALA A 1 379 ? -89.719  11.522  85.361  1.00 57.94  ? 439 ALA A CA  1 
ATOM   2891  C C   . ALA A 1 379 ? -91.133  11.526  85.959  1.00 58.23  ? 439 ALA A C   1 
ATOM   2892  O O   . ALA A 1 379 ? -91.893  12.470  85.689  1.00 69.11  ? 439 ALA A O   1 
ATOM   2893  C CB  . ALA A 1 379 ? -89.426  12.828  84.654  1.00 58.95  ? 439 ALA A CB  1 
ATOM   2894  N N   . HIS A 1 380 ? -91.459  10.532  86.779  1.00 53.05  ? 440 HIS A N   1 
ATOM   2895  C CA  . HIS A 1 380 ? -92.747  10.426  87.500  1.00 53.06  ? 440 HIS A CA  1 
ATOM   2896  C C   . HIS A 1 380 ? -92.819  11.550  88.541  1.00 64.79  ? 440 HIS A C   1 
ATOM   2897  O O   . HIS A 1 380 ? -91.913  12.406  88.558  1.00 74.09  ? 440 HIS A O   1 
ATOM   2898  C CB  . HIS A 1 380 ? -92.885  9.013   88.087  1.00 57.79  ? 440 HIS A CB  1 
ATOM   2899  C CG  . HIS A 1 380 ? -92.543  7.947   87.102  1.00 60.00  ? 440 HIS A CG  1 
ATOM   2900  N ND1 . HIS A 1 380 ? -93.010  7.964   85.807  1.00 65.72  ? 440 HIS A ND1 1 
ATOM   2901  C CD2 . HIS A 1 380 ? -91.760  6.859   87.205  1.00 57.11  ? 440 HIS A CD2 1 
ATOM   2902  C CE1 . HIS A 1 380 ? -92.530  6.931   85.156  1.00 61.46  ? 440 HIS A CE1 1 
ATOM   2903  N NE2 . HIS A 1 380 ? -91.757  6.242   85.990  1.00 53.60  ? 440 HIS A NE2 1 
ATOM   2904  N N   . GLU A 1 381 ? -93.874  11.568  89.355  1.00 71.86  ? 441 GLU A N   1 
ATOM   2905  C CA  . GLU A 1 381 ? -94.184  12.623  90.353  1.00 64.77  ? 441 GLU A CA  1 
ATOM   2906  C C   . GLU A 1 381 ? -93.789  12.149  91.758  1.00 64.27  ? 441 GLU A C   1 
ATOM   2907  O O   . GLU A 1 381 ? -94.347  11.117  92.208  1.00 81.23  ? 441 GLU A O   1 
ATOM   2908  C CB  . GLU A 1 381 ? -95.681  12.937  90.288  1.00 69.45  ? 441 GLU A CB  1 
ATOM   2909  C CG  . GLU A 1 381 ? -96.035  14.217  89.537  1.00 76.66  ? 441 GLU A CG  1 
ATOM   2910  C CD  . GLU A 1 381 ? -95.595  15.504  90.224  1.00 80.95  ? 441 GLU A CD  1 
ATOM   2911  O OE1 . GLU A 1 381 ? -95.551  15.529  91.490  1.00 91.98  ? 441 GLU A OE1 1 
ATOM   2912  O OE2 . GLU A 1 381 ? -95.269  16.481  89.497  1.00 68.29  ? 441 GLU A OE2 1 
ATOM   2913  N N   . HIS A 1 382 ? -92.851  12.839  92.407  1.00 63.09  ? 442 HIS A N   1 
ATOM   2914  C CA  . HIS A 1 382 ? -92.133  12.372  93.628  1.00 63.24  ? 442 HIS A CA  1 
ATOM   2915  C C   . HIS A 1 382 ? -91.243  13.497  94.141  1.00 59.36  ? 442 HIS A C   1 
ATOM   2916  O O   . HIS A 1 382 ? -90.962  14.404  93.359  1.00 54.34  ? 442 HIS A O   1 
ATOM   2917  C CB  . HIS A 1 382 ? -91.274  11.125  93.344  1.00 59.99  ? 442 HIS A CB  1 
ATOM   2918  C CG  . HIS A 1 382 ? -91.094  10.252  94.532  1.00 54.14  ? 442 HIS A CG  1 
ATOM   2919  N ND1 . HIS A 1 382 ? -90.128  10.470  95.471  1.00 57.53  ? 442 HIS A ND1 1 
ATOM   2920  C CD2 . HIS A 1 382 ? -91.781  9.164   94.928  1.00 61.49  ? 442 HIS A CD2 1 
ATOM   2921  C CE1 . HIS A 1 382 ? -90.219  9.546   96.402  1.00 70.89  ? 442 HIS A CE1 1 
ATOM   2922  N NE2 . HIS A 1 382 ? -91.223  8.724   96.095  1.00 64.41  ? 442 HIS A NE2 1 
ATOM   2923  N N   . GLU A 1 383 ? -90.831  13.442  95.405  1.00 62.56  ? 443 GLU A N   1 
ATOM   2924  C CA  . GLU A 1 383 ? -89.980  14.502  95.988  1.00 74.01  ? 443 GLU A CA  1 
ATOM   2925  C C   . GLU A 1 383 ? -88.558  14.265  95.489  1.00 69.79  ? 443 GLU A C   1 
ATOM   2926  O O   . GLU A 1 383 ? -88.207  13.102  95.267  1.00 72.39  ? 443 GLU A O   1 
ATOM   2927  C CB  . GLU A 1 383 ? -90.154  14.505  97.509  1.00 88.68  ? 443 GLU A CB  1 
ATOM   2928  C CG  . GLU A 1 383 ? -88.843  14.545  98.300  1.00 92.83  ? 443 GLU A CG  1 
ATOM   2929  C CD  . GLU A 1 383 ? -88.768  13.764  99.617  1.00 88.38  ? 443 GLU A CD  1 
ATOM   2930  O OE1 . GLU A 1 383 ? -89.369  12.619  99.719  1.00 73.51  ? 443 GLU A OE1 1 
ATOM   2931  O OE2 . GLU A 1 383 ? -88.059  14.282  100.546 1.00 76.82  ? 443 GLU A OE2 1 
ATOM   2932  N N   . PRO A 1 384 ? -87.738  15.326  95.255  1.00 69.77  ? 444 PRO A N   1 
ATOM   2933  C CA  . PRO A 1 384 ? -86.315  15.153  94.930  1.00 67.54  ? 444 PRO A CA  1 
ATOM   2934  C C   . PRO A 1 384 ? -85.622  14.250  95.962  1.00 66.44  ? 444 PRO A C   1 
ATOM   2935  O O   . PRO A 1 384 ? -85.748  14.567  97.117  1.00 64.26  ? 444 PRO A O   1 
ATOM   2936  C CB  . PRO A 1 384 ? -85.724  16.576  94.957  1.00 65.57  ? 444 PRO A CB  1 
ATOM   2937  C CG  . PRO A 1 384 ? -86.924  17.496  94.756  1.00 74.49  ? 444 PRO A CG  1 
ATOM   2938  C CD  . PRO A 1 384 ? -88.135  16.745  95.293  1.00 71.90  ? 444 PRO A CD  1 
ATOM   2939  N N   . LEU A 1 385 ? -84.983  13.154  95.538  1.00 65.44  ? 445 LEU A N   1 
ATOM   2940  C CA  . LEU A 1 385 ? -84.155  12.283  96.411  1.00 64.55  ? 445 LEU A CA  1 
ATOM   2941  C C   . LEU A 1 385 ? -82.730  12.311  95.880  1.00 65.24  ? 445 LEU A C   1 
ATOM   2942  O O   . LEU A 1 385 ? -82.593  12.306  94.653  1.00 67.85  ? 445 LEU A O   1 
ATOM   2943  C CB  . LEU A 1 385 ? -84.701  10.854  96.453  1.00 66.12  ? 445 LEU A CB  1 
ATOM   2944  C CG  . LEU A 1 385 ? -85.601  10.585  97.648  1.00 65.27  ? 445 LEU A CG  1 
ATOM   2945  C CD1 . LEU A 1 385 ? -86.680  11.617  97.703  1.00 68.29  ? 445 LEU A CD1 1 
ATOM   2946  C CD2 . LEU A 1 385 ? -86.205  9.206   97.579  1.00 71.35  ? 445 LEU A CD2 1 
ATOM   2947  N N   . LYS A 1 386 ? -81.722  12.322  96.773  1.00 67.04  ? 446 LYS A N   1 
ATOM   2948  C CA  . LYS A 1 386 ? -80.326  12.571  96.345  1.00 69.19  ? 446 LYS A CA  1 
ATOM   2949  C C   . LYS A 1 386 ? -79.628  11.227  96.141  1.00 63.03  ? 446 LYS A C   1 
ATOM   2950  O O   . LYS A 1 386 ? -78.921  11.170  95.149  1.00 90.07  ? 446 LYS A O   1 
ATOM   2951  C CB  . LYS A 1 386 ? -79.581  13.585  97.227  1.00 76.71  ? 446 LYS A CB  1 
ATOM   2952  C CG  . LYS A 1 386 ? -78.972  14.752  96.445  1.00 86.15  ? 446 LYS A CG  1 
ATOM   2953  C CD  . LYS A 1 386 ? -78.088  14.283  95.272  1.00 105.16 ? 446 LYS A CD  1 
ATOM   2954  C CE  . LYS A 1 386 ? -77.245  15.354  94.597  1.00 97.01  ? 446 LYS A CE  1 
ATOM   2955  N NZ  . LYS A 1 386 ? -76.355  14.767  93.559  1.00 86.07  ? 446 LYS A NZ  1 
ATOM   2956  N N   . THR A 1 387 ? -79.814  10.210  96.977  1.00 55.17  ? 447 THR A N   1 
ATOM   2957  C CA  . THR A 1 387 ? -79.004  8.961   96.905  1.00 54.09  ? 447 THR A CA  1 
ATOM   2958  C C   . THR A 1 387 ? -79.880  7.749   96.596  1.00 50.29  ? 447 THR A C   1 
ATOM   2959  O O   . THR A 1 387 ? -81.067  7.801   96.936  1.00 54.74  ? 447 THR A O   1 
ATOM   2960  C CB  . THR A 1 387 ? -78.282  8.695   98.223  1.00 58.18  ? 447 THR A CB  1 
ATOM   2961  O OG1 . THR A 1 387 ? -79.326  8.533   99.183  1.00 63.63  ? 447 THR A OG1 1 
ATOM   2962  C CG2 . THR A 1 387 ? -77.358  9.812   98.651  1.00 61.72  ? 447 THR A CG2 1 
ATOM   2963  N N   . LEU A 1 388 ? -79.282  6.700   96.033  1.00 53.48  ? 448 LEU A N   1 
ATOM   2964  C CA  . LEU A 1 388 ? -79.932  5.379   95.815  1.00 58.85  ? 448 LEU A CA  1 
ATOM   2965  C C   . LEU A 1 388 ? -80.514  4.887   97.133  1.00 52.00  ? 448 LEU A C   1 
ATOM   2966  O O   . LEU A 1 388 ? -81.634  4.370   97.106  1.00 47.03  ? 448 LEU A O   1 
ATOM   2967  C CB  . LEU A 1 388 ? -78.949  4.331   95.274  1.00 63.21  ? 448 LEU A CB  1 
ATOM   2968  C CG  . LEU A 1 388 ? -79.484  2.896   95.229  1.00 63.94  ? 448 LEU A CG  1 
ATOM   2969  C CD1 . LEU A 1 388 ? -80.650  2.783   94.262  1.00 72.07  ? 448 LEU A CD1 1 
ATOM   2970  C CD2 . LEU A 1 388 ? -78.405  1.933   94.818  1.00 69.14  ? 448 LEU A CD2 1 
ATOM   2971  N N   . TYR A 1 389 ? -79.792  5.043   98.238  1.00 55.48  ? 449 TYR A N   1 
ATOM   2972  C CA  . TYR A 1 389 ? -80.298  4.578   99.556  1.00 65.10  ? 449 TYR A CA  1 
ATOM   2973  C C   . TYR A 1 389 ? -81.651  5.253   99.864  1.00 64.06  ? 449 TYR A C   1 
ATOM   2974  O O   . TYR A 1 389 ? -82.554  4.574   100.362 1.00 69.95  ? 449 TYR A O   1 
ATOM   2975  C CB  . TYR A 1 389 ? -79.270  4.808   100.667 1.00 66.39  ? 449 TYR A CB  1 
ATOM   2976  C CG  . TYR A 1 389 ? -79.786  4.452   102.035 1.00 64.81  ? 449 TYR A CG  1 
ATOM   2977  C CD1 . TYR A 1 389 ? -79.873  3.125   102.451 1.00 64.09  ? 449 TYR A CD1 1 
ATOM   2978  C CD2 . TYR A 1 389 ? -80.257  5.447   102.876 1.00 60.89  ? 449 TYR A CD2 1 
ATOM   2979  C CE1 . TYR A 1 389 ? -80.422  2.796   103.682 1.00 60.55  ? 449 TYR A CE1 1 
ATOM   2980  C CE2 . TYR A 1 389 ? -80.801  5.137   104.106 1.00 63.05  ? 449 TYR A CE2 1 
ATOM   2981  C CZ  . TYR A 1 389 ? -80.873  3.812   104.514 1.00 64.21  ? 449 TYR A CZ  1 
ATOM   2982  O OH  . TYR A 1 389 ? -81.441  3.547   105.726 1.00 62.97  ? 449 TYR A OH  1 
ATOM   2983  N N   . ASP A 1 390 ? -81.796  6.545   99.579  1.00 58.04  ? 450 ASP A N   1 
ATOM   2984  C CA  . ASP A 1 390 ? -83.032  7.309   99.888  1.00 55.63  ? 450 ASP A CA  1 
ATOM   2985  C C   . ASP A 1 390 ? -84.163  6.785   99.023  1.00 47.79  ? 450 ASP A C   1 
ATOM   2986  O O   . ASP A 1 390 ? -85.269  6.531   99.556  1.00 45.67  ? 450 ASP A O   1 
ATOM   2987  C CB  . ASP A 1 390 ? -82.852  8.809   99.650  1.00 57.39  ? 450 ASP A CB  1 
ATOM   2988  C CG  . ASP A 1 390 ? -81.979  9.441   100.719 1.00 59.91  ? 450 ASP A CG  1 
ATOM   2989  O OD1 . ASP A 1 390 ? -81.592  8.729   101.707 1.00 57.62  ? 450 ASP A OD1 1 
ATOM   2990  O OD2 . ASP A 1 390 ? -81.654  10.619  100.536 1.00 66.20  ? 450 ASP A OD2 1 
ATOM   2991  N N   . ALA A 1 391 ? -83.897  6.643   97.731  1.00 47.87  ? 451 ALA A N   1 
ATOM   2992  C CA  . ALA A 1 391 ? -84.865  6.047   96.787  1.00 52.72  ? 451 ALA A CA  1 
ATOM   2993  C C   . ALA A 1 391 ? -85.234  4.639   97.288  1.00 47.27  ? 451 ALA A C   1 
ATOM   2994  O O   . ALA A 1 391 ? -86.424  4.382   97.392  1.00 60.85  ? 451 ALA A O   1 
ATOM   2995  C CB  . ALA A 1 391 ? -84.339  6.072   95.367  1.00 51.51  ? 451 ALA A CB  1 
ATOM   2996  N N   . VAL A 1 392 ? -84.277  3.775   97.636  1.00 42.99  ? 452 VAL A N   1 
ATOM   2997  C CA  . VAL A 1 392 ? -84.599  2.353   97.949  1.00 48.12  ? 452 VAL A CA  1 
ATOM   2998  C C   . VAL A 1 392 ? -85.644  2.376   99.075  1.00 57.92  ? 452 VAL A C   1 
ATOM   2999  O O   . VAL A 1 392 ? -86.621  1.554   99.055  1.00 54.00  ? 452 VAL A O   1 
ATOM   3000  C CB  . VAL A 1 392 ? -83.369  1.501   98.312  1.00 46.07  ? 452 VAL A CB  1 
ATOM   3001  C CG1 . VAL A 1 392 ? -83.750  0.197   98.984  1.00 46.13  ? 452 VAL A CG1 1 
ATOM   3002  C CG2 . VAL A 1 392 ? -82.527  1.184   97.097  1.00 48.68  ? 452 VAL A CG2 1 
ATOM   3003  N N   . GLN A 1 393 ? -85.476  3.309   100.014 1.00 56.70  ? 453 GLN A N   1 
ATOM   3004  C CA  . GLN A 1 393 ? -86.282  3.320   101.265 1.00 51.17  ? 453 GLN A CA  1 
ATOM   3005  C C   . GLN A 1 393 ? -87.654  3.930   100.963 1.00 49.93  ? 453 GLN A C   1 
ATOM   3006  O O   . GLN A 1 393 ? -88.634  3.407   101.502 1.00 48.79  ? 453 GLN A O   1 
ATOM   3007  C CB  . GLN A 1 393 ? -85.552  4.023   102.407 1.00 47.38  ? 453 GLN A CB  1 
ATOM   3008  C CG  . GLN A 1 393 ? -84.322  3.272   102.874 1.00 53.60  ? 453 GLN A CG  1 
ATOM   3009  C CD  . GLN A 1 393 ? -84.553  2.036   103.717 1.00 60.12  ? 453 GLN A CD  1 
ATOM   3010  O OE1 . GLN A 1 393 ? -85.155  1.057   103.278 1.00 54.80  ? 453 GLN A OE1 1 
ATOM   3011  N NE2 . GLN A 1 393 ? -83.951  2.038   104.901 1.00 59.91  ? 453 GLN A NE2 1 
ATOM   3012  N N   . SER A 1 394 ? -87.729  4.957   100.111 1.00 49.25  ? 454 SER A N   1 
ATOM   3013  C CA  . SER A 1 394 ? -88.988  5.671   99.760  1.00 52.20  ? 454 SER A CA  1 
ATOM   3014  C C   . SER A 1 394 ? -89.834  4.813   98.798  1.00 47.55  ? 454 SER A C   1 
ATOM   3015  O O   . SER A 1 394 ? -90.998  4.540   99.115  1.00 47.31  ? 454 SER A O   1 
ATOM   3016  C CB  . SER A 1 394 ? -88.692  7.052   99.193  1.00 53.65  ? 454 SER A CB  1 
ATOM   3017  O OG  . SER A 1 394 ? -89.892  7.749   98.905  1.00 53.00  ? 454 SER A OG  1 
ATOM   3018  N N   . ILE A 1 395 ? -89.257  4.381   97.678  1.00 48.18  ? 455 ILE A N   1 
ATOM   3019  C CA  . ILE A 1 395 ? -89.946  3.654   96.566  1.00 50.64  ? 455 ILE A CA  1 
ATOM   3020  C C   . ILE A 1 395 ? -90.306  2.242   97.042  1.00 44.21  ? 455 ILE A C   1 
ATOM   3021  O O   . ILE A 1 395 ? -91.283  1.693   96.556  1.00 40.03  ? 455 ILE A O   1 
ATOM   3022  C CB  . ILE A 1 395 ? -89.071  3.569   95.289  1.00 57.59  ? 455 ILE A CB  1 
ATOM   3023  C CG1 . ILE A 1 395 ? -88.769  4.893   94.549  1.00 58.33  ? 455 ILE A CG1 1 
ATOM   3024  C CG2 . ILE A 1 395 ? -89.640  2.515   94.359  1.00 58.32  ? 455 ILE A CG2 1 
ATOM   3025  C CD1 . ILE A 1 395 ? -89.847  5.928   94.509  1.00 59.03  ? 455 ILE A CD1 1 
ATOM   3026  N N   . LYS A 1 396 ? -89.519  1.649   97.931  1.00 52.06  ? 456 LYS A N   1 
ATOM   3027  C CA  . LYS A 1 396 ? -89.750  0.267   98.444  1.00 59.37  ? 456 LYS A CA  1 
ATOM   3028  C C   . LYS A 1 396 ? -89.842  -0.691  97.263  1.00 53.02  ? 456 LYS A C   1 
ATOM   3029  O O   . LYS A 1 396 ? -90.768  -1.475  97.182  1.00 55.18  ? 456 LYS A O   1 
ATOM   3030  C CB  . LYS A 1 396 ? -91.034  0.195   99.284  1.00 67.53  ? 456 LYS A CB  1 
ATOM   3031  C CG  . LYS A 1 396 ? -90.913  -0.000  100.794 1.00 69.97  ? 456 LYS A CG  1 
ATOM   3032  C CD  . LYS A 1 396 ? -90.328  1.177   101.495 1.00 85.98  ? 456 LYS A CD  1 
ATOM   3033  C CE  . LYS A 1 396 ? -90.096  0.939   102.973 1.00 104.80 ? 456 LYS A CE  1 
ATOM   3034  N NZ  . LYS A 1 396 ? -88.984  1.773   103.519 1.00 110.62 ? 456 LYS A NZ  1 
ATOM   3035  N N   . PRO A 1 397 ? -88.855  -0.706  96.347  1.00 54.33  ? 457 PRO A N   1 
ATOM   3036  C CA  . PRO A 1 397 ? -88.936  -1.530  95.138  1.00 55.69  ? 457 PRO A CA  1 
ATOM   3037  C C   . PRO A 1 397 ? -88.857  -3.055  95.380  1.00 53.96  ? 457 PRO A C   1 
ATOM   3038  O O   . PRO A 1 397 ? -88.387  -3.480  96.398  1.00 52.34  ? 457 PRO A O   1 
ATOM   3039  C CB  . PRO A 1 397 ? -87.696  -1.056  94.354  1.00 57.08  ? 457 PRO A CB  1 
ATOM   3040  C CG  . PRO A 1 397 ? -86.705  -0.681  95.431  1.00 55.79  ? 457 PRO A CG  1 
ATOM   3041  C CD  . PRO A 1 397 ? -87.563  -0.015  96.483  1.00 57.54  ? 457 PRO A CD  1 
ATOM   3042  N N   . THR A 1 398 ? -89.332  -3.845  94.423  1.00 54.19  ? 458 THR A N   1 
ATOM   3043  C CA  . THR A 1 398 ? -89.265  -5.335  94.439  1.00 61.00  ? 458 THR A CA  1 
ATOM   3044  C C   . THR A 1 398 ? -88.047  -5.802  93.636  1.00 61.37  ? 458 THR A C   1 
ATOM   3045  O O   . THR A 1 398 ? -87.626  -6.961  93.837  1.00 59.25  ? 458 THR A O   1 
ATOM   3046  C CB  . THR A 1 398 ? -90.565  -6.004  93.946  1.00 60.03  ? 458 THR A CB  1 
ATOM   3047  O OG1 . THR A 1 398 ? -90.868  -5.715  92.575  1.00 57.30  ? 458 THR A OG1 1 
ATOM   3048  C CG2 . THR A 1 398 ? -91.745  -5.587  94.797  1.00 58.74  ? 458 THR A CG2 1 
ATOM   3049  N N   . VAL A 1 399 ? -87.533  -4.937  92.758  1.00 59.94  ? 459 VAL A N   1 
ATOM   3050  C CA  . VAL A 1 399 ? -86.428  -5.240  91.801  1.00 58.82  ? 459 VAL A CA  1 
ATOM   3051  C C   . VAL A 1 399 ? -85.466  -4.049  91.772  1.00 56.72  ? 459 VAL A C   1 
ATOM   3052  O O   . VAL A 1 399 ? -85.920  -2.913  91.453  1.00 44.98  ? 459 VAL A O   1 
ATOM   3053  C CB  . VAL A 1 399 ? -86.943  -5.533  90.382  1.00 58.86  ? 459 VAL A CB  1 
ATOM   3054  C CG1 . VAL A 1 399 ? -85.802  -5.795  89.426  1.00 56.01  ? 459 VAL A CG1 1 
ATOM   3055  C CG2 . VAL A 1 399 ? -87.942  -6.674  90.358  1.00 61.13  ? 459 VAL A CG2 1 
ATOM   3056  N N   . LEU A 1 400 ? -84.195  -4.334  92.081  1.00 50.32  ? 460 LEU A N   1 
ATOM   3057  C CA  . LEU A 1 400 ? -83.078  -3.368  92.068  1.00 50.56  ? 460 LEU A CA  1 
ATOM   3058  C C   . LEU A 1 400 ? -82.085  -3.794  90.998  1.00 51.77  ? 460 LEU A C   1 
ATOM   3059  O O   . LEU A 1 400 ? -81.419  -4.833  91.181  1.00 56.70  ? 460 LEU A O   1 
ATOM   3060  C CB  . LEU A 1 400 ? -82.414  -3.358  93.446  1.00 52.17  ? 460 LEU A CB  1 
ATOM   3061  C CG  . LEU A 1 400 ? -81.283  -2.358  93.619  1.00 47.69  ? 460 LEU A CG  1 
ATOM   3062  C CD1 . LEU A 1 400 ? -81.762  -0.924  93.479  1.00 47.91  ? 460 LEU A CD1 1 
ATOM   3063  C CD2 . LEU A 1 400 ? -80.611  -2.562  94.970  1.00 45.92  ? 460 LEU A CD2 1 
ATOM   3064  N N   . ILE A 1 401 ? -81.973  -2.997  89.940  1.00 55.33  ? 461 ILE A N   1 
ATOM   3065  C CA  . ILE A 1 401 ? -81.041  -3.239  88.800  1.00 58.57  ? 461 ILE A CA  1 
ATOM   3066  C C   . ILE A 1 401 ? -79.986  -2.126  88.762  1.00 62.41  ? 461 ILE A C   1 
ATOM   3067  O O   . ILE A 1 401 ? -80.365  -0.937  88.785  1.00 63.44  ? 461 ILE A O   1 
ATOM   3068  C CB  . ILE A 1 401 ? -81.818  -3.348  87.480  1.00 55.64  ? 461 ILE A CB  1 
ATOM   3069  C CG1 . ILE A 1 401 ? -82.731  -4.575  87.428  1.00 57.18  ? 461 ILE A CG1 1 
ATOM   3070  C CG2 . ILE A 1 401 ? -80.867  -3.350  86.319  1.00 55.32  ? 461 ILE A CG2 1 
ATOM   3071  C CD1 . ILE A 1 401 ? -83.809  -4.478  86.374  1.00 56.10  ? 461 ILE A CD1 1 
ATOM   3072  N N   . GLY A 1 402 ? -78.711  -2.517  88.732  1.00 55.83  ? 462 GLY A N   1 
ATOM   3073  C CA  . GLY A 1 402 ? -77.572  -1.595  88.691  1.00 57.93  ? 462 GLY A CA  1 
ATOM   3074  C C   . GLY A 1 402 ? -76.909  -1.592  87.326  1.00 59.40  ? 462 GLY A C   1 
ATOM   3075  O O   . GLY A 1 402 ? -76.368  -2.627  86.915  1.00 59.87  ? 462 GLY A O   1 
ATOM   3076  N N   . THR A 1 403 ? -76.910  -0.440  86.675  1.00 56.20  ? 463 THR A N   1 
ATOM   3077  C CA  . THR A 1 403 ? -76.218  -0.185  85.396  1.00 65.68  ? 463 THR A CA  1 
ATOM   3078  C C   . THR A 1 403 ? -75.395  1.106   85.541  1.00 66.46  ? 463 THR A C   1 
ATOM   3079  O O   . THR A 1 403 ? -75.436  1.923   84.629  1.00 79.61  ? 463 THR A O   1 
ATOM   3080  C CB  . THR A 1 403 ? -77.265  -0.139  84.273  1.00 77.12  ? 463 THR A CB  1 
ATOM   3081  O OG1 . THR A 1 403 ? -76.768  0.606   83.162  1.00 96.87  ? 463 THR A OG1 1 
ATOM   3082  C CG2 . THR A 1 403 ? -78.582  0.472   84.704  1.00 78.84  ? 463 THR A CG2 1 
ATOM   3083  N N   . SER A 1 404 ? -74.691  1.297   86.657  1.00 71.63  ? 464 SER A N   1 
ATOM   3084  C CA  . SER A 1 404 ? -74.064  2.591   87.056  1.00 61.67  ? 464 SER A CA  1 
ATOM   3085  C C   . SER A 1 404 ? -72.676  2.726   86.451  1.00 63.38  ? 464 SER A C   1 
ATOM   3086  O O   . SER A 1 404 ? -72.222  3.867   86.274  1.00 72.06  ? 464 SER A O   1 
ATOM   3087  C CB  . SER A 1 404 ? -73.975  2.724   88.553  1.00 60.09  ? 464 SER A CB  1 
ATOM   3088  O OG  . SER A 1 404 ? -73.726  1.457   89.173  1.00 62.07  ? 464 SER A OG  1 
ATOM   3089  N N   . GLY A 1 405 ? -72.015  1.586   86.226  1.00 65.63  ? 465 GLY A N   1 
ATOM   3090  C CA  . GLY A 1 405 ? -70.578  1.475   85.920  1.00 60.98  ? 465 GLY A CA  1 
ATOM   3091  C C   . GLY A 1 405 ? -69.700  1.721   87.142  1.00 55.73  ? 465 GLY A C   1 
ATOM   3092  O O   . GLY A 1 405 ? -68.486  1.918   86.967  1.00 58.52  ? 465 GLY A O   1 
ATOM   3093  N N   . VAL A 1 406 ? -70.280  1.717   88.342  1.00 53.84  ? 466 VAL A N   1 
ATOM   3094  C CA  . VAL A 1 406 ? -69.599  2.082   89.624  1.00 51.60  ? 466 VAL A CA  1 
ATOM   3095  C C   . VAL A 1 406 ? -69.708  0.895   90.583  1.00 51.23  ? 466 VAL A C   1 
ATOM   3096  O O   . VAL A 1 406 ? -70.825  0.418   90.849  1.00 45.20  ? 466 VAL A O   1 
ATOM   3097  C CB  . VAL A 1 406 ? -70.167  3.359   90.269  1.00 44.87  ? 466 VAL A CB  1 
ATOM   3098  C CG1 . VAL A 1 406 ? -69.319  3.763   91.449  1.00 42.68  ? 466 VAL A CG1 1 
ATOM   3099  C CG2 . VAL A 1 406 ? -70.285  4.496   89.265  1.00 45.73  ? 466 VAL A CG2 1 
ATOM   3100  N N   . GLY A 1 407 ? -68.564  0.438   91.073  1.00 53.76  ? 467 GLY A N   1 
ATOM   3101  C CA  . GLY A 1 407 ? -68.494  -0.752  91.919  1.00 53.80  ? 467 GLY A CA  1 
ATOM   3102  C C   . GLY A 1 407 ? -68.967  -0.427  93.313  1.00 62.32  ? 467 GLY A C   1 
ATOM   3103  O O   . GLY A 1 407 ? -68.865  0.774   93.719  1.00 71.25  ? 467 GLY A O   1 
ATOM   3104  N N   . ARG A 1 408 ? -69.505  -1.442  93.993  1.00 64.61  ? 468 ARG A N   1 
ATOM   3105  C CA  . ARG A 1 408 ? -69.777  -1.420  95.448  1.00 63.69  ? 468 ARG A CA  1 
ATOM   3106  C C   . ARG A 1 408 ? -70.725  -0.237  95.784  1.00 54.51  ? 468 ARG A C   1 
ATOM   3107  O O   . ARG A 1 408 ? -70.558  0.373   96.859  1.00 57.70  ? 468 ARG A O   1 
ATOM   3108  C CB  . ARG A 1 408 ? -68.408  -1.436  96.152  1.00 60.32  ? 468 ARG A CB  1 
ATOM   3109  C CG  . ARG A 1 408 ? -67.458  -2.529  95.675  1.00 72.32  ? 468 ARG A CG  1 
ATOM   3110  C CD  . ARG A 1 408 ? -67.198  -3.531  96.800  1.00 95.41  ? 468 ARG A CD  1 
ATOM   3111  N NE  . ARG A 1 408 ? -66.209  -4.623  96.630  1.00 100.97 ? 468 ARG A NE  1 
ATOM   3112  C CZ  . ARG A 1 408 ? -65.535  -5.219  97.638  1.00 72.83  ? 468 ARG A CZ  1 
ATOM   3113  N NH1 . ARG A 1 408 ? -65.693  -4.799  98.883  1.00 71.64  ? 468 ARG A NH1 1 
ATOM   3114  N NH2 . ARG A 1 408 ? -64.720  -6.234  97.404  1.00 61.87  ? 468 ARG A NH2 1 
ATOM   3115  N N   . THR A 1 409 ? -71.704  0.069   94.913  1.00 45.51  ? 469 THR A N   1 
ATOM   3116  C CA  . THR A 1 409 ? -72.766  1.091   95.139  1.00 47.03  ? 469 THR A CA  1 
ATOM   3117  C C   . THR A 1 409 ? -74.037  0.438   95.701  1.00 48.93  ? 469 THR A C   1 
ATOM   3118  O O   . THR A 1 409 ? -74.889  1.173   96.263  1.00 47.91  ? 469 THR A O   1 
ATOM   3119  C CB  . THR A 1 409 ? -73.096  1.873   93.864  1.00 47.92  ? 469 THR A CB  1 
ATOM   3120  O OG1 . THR A 1 409 ? -73.260  0.896   92.834  1.00 49.81  ? 469 THR A OG1 1 
ATOM   3121  C CG2 . THR A 1 409 ? -72.038  2.891   93.496  1.00 44.19  ? 469 THR A CG2 1 
ATOM   3122  N N   . PHE A 1 410 ? -74.160  -0.881  95.535  1.00 56.21  ? 470 PHE A N   1 
ATOM   3123  C CA  . PHE A 1 410 ? -75.114  -1.763  96.268  1.00 53.99  ? 470 PHE A CA  1 
ATOM   3124  C C   . PHE A 1 410 ? -74.453  -2.159  97.583  1.00 53.12  ? 470 PHE A C   1 
ATOM   3125  O O   . PHE A 1 410 ? -73.747  -3.194  97.611  1.00 56.76  ? 470 PHE A O   1 
ATOM   3126  C CB  . PHE A 1 410 ? -75.547  -2.980  95.436  1.00 48.67  ? 470 PHE A CB  1 
ATOM   3127  C CG  . PHE A 1 410 ? -76.464  -2.646  94.281  1.00 42.87  ? 470 PHE A CG  1 
ATOM   3128  C CD1 . PHE A 1 410 ? -76.681  -1.319  93.894  1.00 38.81  ? 470 PHE A CD1 1 
ATOM   3129  C CD2 . PHE A 1 410 ? -77.059  -3.658  93.548  1.00 39.28  ? 470 PHE A CD2 1 
ATOM   3130  C CE1 . PHE A 1 410 ? -77.487  -1.004  92.819  1.00 40.33  ? 470 PHE A CE1 1 
ATOM   3131  C CE2 . PHE A 1 410 ? -77.851  -3.348  92.449  1.00 46.51  ? 470 PHE A CE2 1 
ATOM   3132  C CZ  . PHE A 1 410 ? -78.066  -2.026  92.088  1.00 48.21  ? 470 PHE A CZ  1 
ATOM   3133  N N   . THR A 1 411 ? -74.680  -1.314  98.600  1.00 53.18  ? 471 THR A N   1 
ATOM   3134  C CA  . THR A 1 411 ? -74.055  -1.334  99.952  1.00 51.70  ? 471 THR A CA  1 
ATOM   3135  C C   . THR A 1 411 ? -74.808  -2.349  100.828 1.00 53.25  ? 471 THR A C   1 
ATOM   3136  O O   . THR A 1 411 ? -75.882  -2.811  100.415 1.00 68.00  ? 471 THR A O   1 
ATOM   3137  C CB  . THR A 1 411 ? -74.019  0.107   100.486 1.00 43.59  ? 471 THR A CB  1 
ATOM   3138  O OG1 . THR A 1 411 ? -75.357  0.578   100.587 1.00 43.91  ? 471 THR A OG1 1 
ATOM   3139  C CG2 . THR A 1 411 ? -73.293  1.074   99.575  1.00 40.02  ? 471 THR A CG2 1 
ATOM   3140  N N   . LYS A 1 412 ? -74.263  -2.688  101.990 1.00 57.04  ? 472 LYS A N   1 
ATOM   3141  C CA  . LYS A 1 412 ? -74.908  -3.550  103.019 1.00 62.35  ? 472 LYS A CA  1 
ATOM   3142  C C   . LYS A 1 412 ? -76.276  -2.940  103.406 1.00 61.49  ? 472 LYS A C   1 
ATOM   3143  O O   . LYS A 1 412 ? -77.272  -3.707  103.381 1.00 67.81  ? 472 LYS A O   1 
ATOM   3144  C CB  . LYS A 1 412 ? -73.879  -3.732  104.150 1.00 60.24  ? 472 LYS A CB  1 
ATOM   3145  C CG  . LYS A 1 412 ? -74.123  -4.812  105.198 1.00 69.43  ? 472 LYS A CG  1 
ATOM   3146  C CD  . LYS A 1 412 ? -72.860  -5.071  106.044 1.00 79.28  ? 472 LYS A CD  1 
ATOM   3147  C CE  . LYS A 1 412 ? -72.947  -6.246  107.002 1.00 80.70  ? 472 LYS A CE  1 
ATOM   3148  N NZ  . LYS A 1 412 ? -73.192  -5.802  108.393 1.00 78.26  ? 472 LYS A NZ  1 
ATOM   3149  N N   . GLU A 1 413 ? -76.326  -1.616  103.664 1.00 59.69  ? 473 GLU A N   1 
ATOM   3150  C CA  . GLU A 1 413 ? -77.558  -0.855  104.025 1.00 62.47  ? 473 GLU A CA  1 
ATOM   3151  C C   . GLU A 1 413 ? -78.638  -1.048  102.963 1.00 56.97  ? 473 GLU A C   1 
ATOM   3152  O O   . GLU A 1 413 ? -79.828  -1.165  103.326 1.00 56.87  ? 473 GLU A O   1 
ATOM   3153  C CB  . GLU A 1 413 ? -77.326  0.662   104.088 1.00 71.23  ? 473 GLU A CB  1 
ATOM   3154  C CG  . GLU A 1 413 ? -76.478  1.105   105.247 1.00 77.16  ? 473 GLU A CG  1 
ATOM   3155  C CD  . GLU A 1 413 ? -75.008  1.098   104.874 1.00 92.90  ? 473 GLU A CD  1 
ATOM   3156  O OE1 . GLU A 1 413 ? -74.532  0.024   104.408 1.00 80.77  ? 473 GLU A OE1 1 
ATOM   3157  O OE2 . GLU A 1 413 ? -74.367  2.175   104.984 1.00 102.14 ? 473 GLU A OE2 1 
ATOM   3158  N N   . ILE A 1 414 ? -78.230  -0.996  101.701 1.00 57.35  ? 474 ILE A N   1 
ATOM   3159  C CA  . ILE A 1 414 ? -79.128  -1.045  100.516 1.00 56.41  ? 474 ILE A CA  1 
ATOM   3160  C C   . ILE A 1 414 ? -79.646  -2.471  100.339 1.00 49.80  ? 474 ILE A C   1 
ATOM   3161  O O   . ILE A 1 414 ? -80.857  -2.613  100.299 1.00 57.65  ? 474 ILE A O   1 
ATOM   3162  C CB  . ILE A 1 414 ? -78.409  -0.478  99.286  1.00 60.45  ? 474 ILE A CB  1 
ATOM   3163  C CG1 . ILE A 1 414 ? -78.279  1.050   99.442  1.00 61.74  ? 474 ILE A CG1 1 
ATOM   3164  C CG2 . ILE A 1 414 ? -79.126  -0.907  98.015  1.00 64.66  ? 474 ILE A CG2 1 
ATOM   3165  C CD1 . ILE A 1 414 ? -77.979  1.793   98.163  1.00 62.74  ? 474 ILE A CD1 1 
ATOM   3166  N N   . ILE A 1 415 ? -78.787  -3.487  100.287 1.00 48.51  ? 475 ILE A N   1 
ATOM   3167  C CA  . ILE A 1 415 ? -79.236  -4.911  100.181 1.00 48.21  ? 475 ILE A CA  1 
ATOM   3168  C C   . ILE A 1 415 ? -80.022  -5.310  101.430 1.00 50.34  ? 475 ILE A C   1 
ATOM   3169  O O   . ILE A 1 415 ? -80.948  -6.105  101.284 1.00 51.68  ? 475 ILE A O   1 
ATOM   3170  C CB  . ILE A 1 415 ? -78.068  -5.872  99.920  1.00 48.46  ? 475 ILE A CB  1 
ATOM   3171  C CG1 . ILE A 1 415 ? -77.572  -5.626  98.492  1.00 43.99  ? 475 ILE A CG1 1 
ATOM   3172  C CG2 . ILE A 1 415 ? -78.463  -7.338  100.143 1.00 47.73  ? 475 ILE A CG2 1 
ATOM   3173  C CD1 . ILE A 1 415 ? -76.551  -6.628  98.033  1.00 50.47  ? 475 ILE A CD1 1 
ATOM   3174  N N   . GLU A 1 416 ? -79.646  -4.818  102.606 1.00 54.33  ? 476 GLU A N   1 
ATOM   3175  C CA  . GLU A 1 416 ? -80.397  -5.115  103.857 1.00 57.43  ? 476 GLU A CA  1 
ATOM   3176  C C   . GLU A 1 416 ? -81.783  -4.460  103.780 1.00 55.72  ? 476 GLU A C   1 
ATOM   3177  O O   . GLU A 1 416 ? -82.766  -5.160  104.039 1.00 60.28  ? 476 GLU A O   1 
ATOM   3178  C CB  . GLU A 1 416 ? -79.626  -4.665  105.092 1.00 62.44  ? 476 GLU A CB  1 
ATOM   3179  C CG  . GLU A 1 416 ? -78.599  -5.666  105.578 1.00 64.39  ? 476 GLU A CG  1 
ATOM   3180  C CD  . GLU A 1 416 ? -78.111  -5.346  106.991 1.00 71.54  ? 476 GLU A CD  1 
ATOM   3181  O OE1 . GLU A 1 416 ? -78.271  -4.177  107.468 1.00 74.35  ? 476 GLU A OE1 1 
ATOM   3182  O OE2 . GLU A 1 416 ? -77.567  -6.259  107.631 1.00 71.79  ? 476 GLU A OE2 1 
ATOM   3183  N N   . ALA A 1 417 ? -81.858  -3.178  103.409 1.00 60.36  ? 477 ALA A N   1 
ATOM   3184  C CA  . ALA A 1 417 ? -83.121  -2.431  103.178 1.00 56.53  ? 477 ALA A CA  1 
ATOM   3185  C C   . ALA A 1 417 ? -84.005  -3.233  102.213 1.00 56.12  ? 477 ALA A C   1 
ATOM   3186  O O   . ALA A 1 417 ? -85.151  -3.467  102.554 1.00 64.28  ? 477 ALA A O   1 
ATOM   3187  C CB  . ALA A 1 417 ? -82.840  -1.055  102.648 1.00 47.88  ? 477 ALA A CB  1 
ATOM   3188  N N   . MET A 1 418 ? -83.470  -3.665  101.074 1.00 52.85  ? 478 MET A N   1 
ATOM   3189  C CA  . MET A 1 418 ? -84.189  -4.466  100.044 1.00 57.17  ? 478 MET A CA  1 
ATOM   3190  C C   . MET A 1 418 ? -84.645  -5.819  100.604 1.00 59.94  ? 478 MET A C   1 
ATOM   3191  O O   . MET A 1 418 ? -85.667  -6.305  100.142 1.00 68.48  ? 478 MET A O   1 
ATOM   3192  C CB  . MET A 1 418 ? -83.303  -4.745  98.828  1.00 54.64  ? 478 MET A CB  1 
ATOM   3193  C CG  . MET A 1 418 ? -83.045  -3.511  97.994  1.00 62.56  ? 478 MET A CG  1 
ATOM   3194  S SD  . MET A 1 418 ? -84.382  -3.062  96.846  1.00 69.42  ? 478 MET A SD  1 
ATOM   3195  C CE  . MET A 1 418 ? -84.897  -4.682  96.269  1.00 62.80  ? 478 MET A CE  1 
ATOM   3196  N N   . SER A 1 419 ? -83.889  -6.423  101.515 1.00 56.36  ? 479 SER A N   1 
ATOM   3197  C CA  . SER A 1 419 ? -84.192  -7.748  102.112 1.00 52.80  ? 479 SER A CA  1 
ATOM   3198  C C   . SER A 1 419 ? -85.273  -7.584  103.193 1.00 47.59  ? 479 SER A C   1 
ATOM   3199  O O   . SER A 1 419 ? -85.897  -8.582  103.569 1.00 49.65  ? 479 SER A O   1 
ATOM   3200  C CB  . SER A 1 419 ? -82.939  -8.421  102.662 1.00 55.92  ? 479 SER A CB  1 
ATOM   3201  O OG  . SER A 1 419 ? -81.864  -8.420  101.725 1.00 59.19  ? 479 SER A OG  1 
ATOM   3202  N N   . SER A 1 420 ? -85.467  -6.364  103.681 1.00 50.60  ? 480 SER A N   1 
ATOM   3203  C CA  . SER A 1 420 ? -86.362  -6.002  104.806 1.00 56.94  ? 480 SER A CA  1 
ATOM   3204  C C   . SER A 1 420 ? -87.837  -5.919  104.332 1.00 63.23  ? 480 SER A C   1 
ATOM   3205  O O   . SER A 1 420 ? -88.709  -6.436  105.058 1.00 65.64  ? 480 SER A O   1 
ATOM   3206  C CB  . SER A 1 420 ? -85.884  -4.724  105.473 1.00 55.21  ? 480 SER A CB  1 
ATOM   3207  O OG  . SER A 1 420 ? -86.883  -4.161  106.300 1.00 73.41  ? 480 SER A OG  1 
ATOM   3208  N N   . PHE A 1 421 ? -88.143  -5.338  103.165 1.00 56.69  ? 481 PHE A N   1 
ATOM   3209  C CA  . PHE A 1 421 ? -89.548  -5.169  102.703 1.00 54.43  ? 481 PHE A CA  1 
ATOM   3210  C C   . PHE A 1 421 ? -89.907  -6.218  101.658 1.00 52.82  ? 481 PHE A C   1 
ATOM   3211  O O   . PHE A 1 421 ? -91.068  -6.581  101.619 1.00 88.77  ? 481 PHE A O   1 
ATOM   3212  C CB  . PHE A 1 421 ? -89.915  -3.752  102.261 1.00 54.73  ? 481 PHE A CB  1 
ATOM   3213  C CG  . PHE A 1 421 ? -88.839  -2.951  101.598 1.00 57.16  ? 481 PHE A CG  1 
ATOM   3214  C CD1 . PHE A 1 421 ? -88.521  -3.207  100.276 1.00 58.73  ? 481 PHE A CD1 1 
ATOM   3215  C CD2 . PHE A 1 421 ? -88.229  -1.884  102.245 1.00 57.20  ? 481 PHE A CD2 1 
ATOM   3216  C CE1 . PHE A 1 421 ? -87.580  -2.439  99.612  1.00 61.33  ? 481 PHE A CE1 1 
ATOM   3217  C CE2 . PHE A 1 421 ? -87.287  -1.112  101.577 1.00 64.38  ? 481 PHE A CE2 1 
ATOM   3218  C CZ  . PHE A 1 421 ? -86.958  -1.401  100.267 1.00 68.98  ? 481 PHE A CZ  1 
ATOM   3219  N N   . ASN A 1 422 ? -88.977  -6.702  100.854 1.00 50.74  ? 482 ASN A N   1 
ATOM   3220  C CA  . ASN A 1 422 ? -89.187  -7.893  99.988  1.00 53.71  ? 482 ASN A CA  1 
ATOM   3221  C C   . ASN A 1 422 ? -88.756  -9.135  100.756 1.00 51.69  ? 482 ASN A C   1 
ATOM   3222  O O   . ASN A 1 422 ? -87.804  -9.051  101.534 1.00 50.43  ? 482 ASN A O   1 
ATOM   3223  C CB  . ASN A 1 422 ? -88.431  -7.782  98.667  1.00 59.63  ? 482 ASN A CB  1 
ATOM   3224  C CG  . ASN A 1 422 ? -88.709  -6.475  97.942  1.00 67.82  ? 482 ASN A CG  1 
ATOM   3225  O OD1 . ASN A 1 422 ? -89.844  -6.188  97.548  1.00 76.96  ? 482 ASN A OD1 1 
ATOM   3226  N ND2 . ASN A 1 422 ? -87.687  -5.652  97.773  1.00 60.00  ? 482 ASN A ND2 1 
ATOM   3227  N N   . GLU A 1 423 ? -89.450  -10.254 100.547 1.00 59.24  ? 483 GLU A N   1 
ATOM   3228  C CA  . GLU A 1 423 ? -89.053  -11.544 101.157 1.00 60.48  ? 483 GLU A CA  1 
ATOM   3229  C C   . GLU A 1 423 ? -87.982  -12.194 100.284 1.00 58.69  ? 483 GLU A C   1 
ATOM   3230  O O   . GLU A 1 423 ? -87.111  -12.843 100.848 1.00 72.45  ? 483 GLU A O   1 
ATOM   3231  C CB  . GLU A 1 423 ? -90.220  -12.496 101.389 1.00 61.49  ? 483 GLU A CB  1 
ATOM   3232  C CG  . GLU A 1 423 ? -89.818  -13.590 102.366 1.00 75.58  ? 483 GLU A CG  1 
ATOM   3233  C CD  . GLU A 1 423 ? -89.910  -15.032 101.868 1.00 94.47  ? 483 GLU A CD  1 
ATOM   3234  O OE1 . GLU A 1 423 ? -91.001  -15.414 101.381 1.00 101.28 ? 483 GLU A OE1 1 
ATOM   3235  O OE2 . GLU A 1 423 ? -88.875  -15.760 101.941 1.00 92.16  ? 483 GLU A OE2 1 
ATOM   3236  N N   . ARG A 1 424 ? -88.052  -12.031 98.962  1.00 62.98  ? 484 ARG A N   1 
ATOM   3237  C CA  . ARG A 1 424 ? -87.025  -12.523 97.999  1.00 59.37  ? 484 ARG A CA  1 
ATOM   3238  C C   . ARG A 1 424 ? -86.677  -11.396 97.034  1.00 56.95  ? 484 ARG A C   1 
ATOM   3239  O O   . ARG A 1 424 ? -87.198  -11.408 95.925  1.00 55.99  ? 484 ARG A O   1 
ATOM   3240  C CB  . ARG A 1 424 ? -87.567  -13.751 97.256  1.00 55.50  ? 484 ARG A CB  1 
ATOM   3241  C CG  . ARG A 1 424 ? -88.122  -14.824 98.175  1.00 56.07  ? 484 ARG A CG  1 
ATOM   3242  C CD  . ARG A 1 424 ? -87.003  -15.661 98.721  1.00 61.30  ? 484 ARG A CD  1 
ATOM   3243  N NE  . ARG A 1 424 ? -86.870  -16.844 97.891  1.00 64.83  ? 484 ARG A NE  1 
ATOM   3244  C CZ  . ARG A 1 424 ? -85.734  -17.392 97.482  1.00 68.32  ? 484 ARG A CZ  1 
ATOM   3245  N NH1 . ARG A 1 424 ? -84.555  -16.851 97.767  1.00 68.59  ? 484 ARG A NH1 1 
ATOM   3246  N NH2 . ARG A 1 424 ? -85.802  -18.501 96.763  1.00 76.93  ? 484 ARG A NH2 1 
ATOM   3247  N N   . PRO A 1 425 ? -85.844  -10.388 97.420  1.00 59.33  ? 485 PRO A N   1 
ATOM   3248  C CA  . PRO A 1 425 ? -85.565  -9.244  96.547  1.00 65.75  ? 485 PRO A CA  1 
ATOM   3249  C C   . PRO A 1 425 ? -84.723  -9.618  95.309  1.00 74.79  ? 485 PRO A C   1 
ATOM   3250  O O   . PRO A 1 425 ? -83.708  -10.306 95.422  1.00 69.80  ? 485 PRO A O   1 
ATOM   3251  C CB  . PRO A 1 425 ? -84.827  -8.223  97.423  1.00 57.14  ? 485 PRO A CB  1 
ATOM   3252  C CG  . PRO A 1 425 ? -84.260  -9.055  98.556  1.00 59.92  ? 485 PRO A CG  1 
ATOM   3253  C CD  . PRO A 1 425 ? -85.135  -10.284 98.700  1.00 57.64  ? 485 PRO A CD  1 
ATOM   3254  N N   . ILE A 1 426 ? -85.166  -9.132  94.149  1.00 72.58  ? 486 ILE A N   1 
ATOM   3255  C CA  . ILE A 1 426 ? -84.503  -9.324  92.833  1.00 64.15  ? 486 ILE A CA  1 
ATOM   3256  C C   . ILE A 1 426 ? -83.417  -8.245  92.740  1.00 61.48  ? 486 ILE A C   1 
ATOM   3257  O O   . ILE A 1 426 ? -83.779  -7.037  92.666  1.00 49.54  ? 486 ILE A O   1 
ATOM   3258  C CB  . ILE A 1 426 ? -85.524  -9.171  91.691  1.00 62.89  ? 486 ILE A CB  1 
ATOM   3259  C CG1 . ILE A 1 426 ? -86.708  -10.137 91.727  1.00 65.75  ? 486 ILE A CG1 1 
ATOM   3260  C CG2 . ILE A 1 426 ? -84.820  -9.204  90.364  1.00 69.59  ? 486 ILE A CG2 1 
ATOM   3261  C CD1 . ILE A 1 426 ? -86.359  -11.530 92.135  1.00 70.15  ? 486 ILE A CD1 1 
ATOM   3262  N N   . ILE A 1 427 ? -82.143  -8.652  92.853  1.00 59.44  ? 487 ILE A N   1 
ATOM   3263  C CA  . ILE A 1 427 ? -80.963  -7.750  92.749  1.00 58.22  ? 487 ILE A CA  1 
ATOM   3264  C C   . ILE A 1 427 ? -80.143  -8.205  91.545  1.00 51.72  ? 487 ILE A C   1 
ATOM   3265  O O   . ILE A 1 427 ? -79.693  -9.387  91.508  1.00 43.77  ? 487 ILE A O   1 
ATOM   3266  C CB  . ILE A 1 427 ? -80.121  -7.688  94.046  1.00 61.37  ? 487 ILE A CB  1 
ATOM   3267  C CG1 . ILE A 1 427 ? -80.980  -7.434  95.280  1.00 55.87  ? 487 ILE A CG1 1 
ATOM   3268  C CG2 . ILE A 1 427 ? -79.065  -6.609  93.970  1.00 60.39  ? 487 ILE A CG2 1 
ATOM   3269  C CD1 . ILE A 1 427 ? -80.363  -7.971  96.498  1.00 59.08  ? 487 ILE A CD1 1 
ATOM   3270  N N   . PHE A 1 428 ? -79.982  -7.266  90.608  1.00 50.18  ? 488 PHE A N   1 
ATOM   3271  C CA  . PHE A 1 428 ? -79.262  -7.403  89.321  1.00 50.65  ? 488 PHE A CA  1 
ATOM   3272  C C   . PHE A 1 428 ? -78.122  -6.380  89.316  1.00 52.58  ? 488 PHE A C   1 
ATOM   3273  O O   . PHE A 1 428 ? -78.384  -5.163  89.207  1.00 47.32  ? 488 PHE A O   1 
ATOM   3274  C CB  . PHE A 1 428 ? -80.231  -7.212  88.153  1.00 53.14  ? 488 PHE A CB  1 
ATOM   3275  C CG  . PHE A 1 428 ? -81.019  -8.430  87.728  1.00 58.78  ? 488 PHE A CG  1 
ATOM   3276  C CD1 . PHE A 1 428 ? -81.144  -9.545  88.544  1.00 57.89  ? 488 PHE A CD1 1 
ATOM   3277  C CD2 . PHE A 1 428 ? -81.684  -8.450  86.521  1.00 65.15  ? 488 PHE A CD2 1 
ATOM   3278  C CE1 . PHE A 1 428 ? -81.859  -10.663 88.142  1.00 54.43  ? 488 PHE A CE1 1 
ATOM   3279  C CE2 . PHE A 1 428 ? -82.398  -9.574  86.120  1.00 71.16  ? 488 PHE A CE2 1 
ATOM   3280  C CZ  . PHE A 1 428 ? -82.484  -10.681 86.933  1.00 57.15  ? 488 PHE A CZ  1 
ATOM   3281  N N   . SER A 1 429 ? -76.889  -6.879  89.473  1.00 54.49  ? 489 SER A N   1 
ATOM   3282  C CA  . SER A 1 429 ? -75.625  -6.102  89.488  1.00 55.66  ? 489 SER A CA  1 
ATOM   3283  C C   . SER A 1 429 ? -74.933  -6.262  88.127  1.00 56.49  ? 489 SER A C   1 
ATOM   3284  O O   . SER A 1 429 ? -74.119  -7.202  87.940  1.00 47.14  ? 489 SER A O   1 
ATOM   3285  C CB  . SER A 1 429 ? -74.766  -6.536  90.625  1.00 56.85  ? 489 SER A CB  1 
ATOM   3286  O OG  . SER A 1 429 ? -73.685  -5.650  90.795  1.00 61.60  ? 489 SER A OG  1 
ATOM   3287  N N   . LEU A 1 430 ? -75.279  -5.374  87.190  1.00 55.21  ? 490 LEU A N   1 
ATOM   3288  C CA  . LEU A 1 430 ? -75.068  -5.614  85.744  1.00 58.29  ? 490 LEU A CA  1 
ATOM   3289  C C   . LEU A 1 430 ? -73.696  -5.094  85.321  1.00 54.31  ? 490 LEU A C   1 
ATOM   3290  O O   . LEU A 1 430 ? -73.115  -5.694  84.427  1.00 49.40  ? 490 LEU A O   1 
ATOM   3291  C CB  . LEU A 1 430 ? -76.197  -4.940  84.953  1.00 65.35  ? 490 LEU A CB  1 
ATOM   3292  C CG  . LEU A 1 430 ? -77.433  -5.789  84.641  1.00 66.76  ? 490 LEU A CG  1 
ATOM   3293  C CD1 . LEU A 1 430 ? -77.327  -6.395  83.255  1.00 76.85  ? 490 LEU A CD1 1 
ATOM   3294  C CD2 . LEU A 1 430 ? -77.643  -6.921  85.620  1.00 76.06  ? 490 LEU A CD2 1 
ATOM   3295  N N   . SER A 1 431 ? -73.201  -4.016  85.928  1.00 55.50  ? 491 SER A N   1 
ATOM   3296  C CA  . SER A 1 431 ? -71.952  -3.337  85.488  1.00 49.69  ? 491 SER A CA  1 
ATOM   3297  C C   . SER A 1 431 ? -70.803  -4.346  85.421  1.00 50.36  ? 491 SER A C   1 
ATOM   3298  O O   . SER A 1 431 ? -70.815  -5.353  86.176  1.00 60.36  ? 491 SER A O   1 
ATOM   3299  C CB  . SER A 1 431 ? -71.606  -2.180  86.366  1.00 46.42  ? 491 SER A CB  1 
ATOM   3300  O OG  . SER A 1 431 ? -72.537  -1.148  86.177  1.00 50.64  ? 491 SER A OG  1 
ATOM   3301  N N   . ASN A 1 432 ? -69.855  -4.069  84.518  1.00 51.71  ? 492 ASN A N   1 
ATOM   3302  C CA  . ASN A 1 432 ? -68.622  -4.854  84.255  1.00 49.77  ? 492 ASN A CA  1 
ATOM   3303  C C   . ASN A 1 432 ? -67.432  -3.895  84.171  1.00 54.72  ? 492 ASN A C   1 
ATOM   3304  O O   . ASN A 1 432 ? -67.571  -2.703  83.861  1.00 55.68  ? 492 ASN A O   1 
ATOM   3305  C CB  . ASN A 1 432 ? -68.747  -5.634  82.949  1.00 53.48  ? 492 ASN A CB  1 
ATOM   3306  C CG  . ASN A 1 432 ? -69.876  -6.632  82.955  1.00 48.86  ? 492 ASN A CG  1 
ATOM   3307  O OD1 . ASN A 1 432 ? -69.979  -7.425  83.882  1.00 61.19  ? 492 ASN A OD1 1 
ATOM   3308  N ND2 . ASN A 1 432 ? -70.719  -6.581  81.939  1.00 47.68  ? 492 ASN A ND2 1 
ATOM   3309  N N   . PRO A 1 433 ? -66.201  -4.382  84.434  1.00 50.08  ? 493 PRO A N   1 
ATOM   3310  C CA  . PRO A 1 433 ? -65.969  -5.774  84.802  1.00 47.26  ? 493 PRO A CA  1 
ATOM   3311  C C   . PRO A 1 433 ? -66.210  -5.956  86.311  1.00 54.08  ? 493 PRO A C   1 
ATOM   3312  O O   . PRO A 1 433 ? -66.806  -5.086  86.901  1.00 62.47  ? 493 PRO A O   1 
ATOM   3313  C CB  . PRO A 1 433 ? -64.514  -5.997  84.383  1.00 49.64  ? 493 PRO A CB  1 
ATOM   3314  C CG  . PRO A 1 433 ? -63.904  -4.626  84.115  1.00 48.63  ? 493 PRO A CG  1 
ATOM   3315  C CD  . PRO A 1 433 ? -64.967  -3.588  84.396  1.00 51.72  ? 493 PRO A CD  1 
ATOM   3316  N N   . THR A 1 434 ? -65.728  -7.057  86.903  1.00 54.08  ? 494 THR A N   1 
ATOM   3317  C CA  . THR A 1 434 ? -65.957  -7.474  88.319  1.00 47.86  ? 494 THR A CA  1 
ATOM   3318  C C   . THR A 1 434 ? -65.703  -6.295  89.268  1.00 42.27  ? 494 THR A C   1 
ATOM   3319  O O   . THR A 1 434 ? -66.517  -6.045  90.113  1.00 46.17  ? 494 THR A O   1 
ATOM   3320  C CB  . THR A 1 434 ? -65.091  -8.700  88.673  1.00 46.00  ? 494 THR A CB  1 
ATOM   3321  O OG1 . THR A 1 434 ? -65.221  -9.690  87.650  1.00 40.40  ? 494 THR A OG1 1 
ATOM   3322  C CG2 . THR A 1 434 ? -65.457  -9.316  90.008  1.00 44.49  ? 494 THR A CG2 1 
ATOM   3323  N N   . SER A 1 435 ? -64.612  -5.573  89.102  1.00 53.12  ? 495 SER A N   1 
ATOM   3324  C CA  . SER A 1 435 ? -64.205  -4.410  89.940  1.00 50.74  ? 495 SER A CA  1 
ATOM   3325  C C   . SER A 1 435 ? -65.231  -3.277  89.858  1.00 49.37  ? 495 SER A C   1 
ATOM   3326  O O   . SER A 1 435 ? -65.197  -2.419  90.740  1.00 61.99  ? 495 SER A O   1 
ATOM   3327  C CB  . SER A 1 435 ? -62.871  -3.899  89.523  1.00 51.89  ? 495 SER A CB  1 
ATOM   3328  O OG  . SER A 1 435 ? -62.991  -3.257  88.266  1.00 59.69  ? 495 SER A OG  1 
ATOM   3329  N N   . HIS A 1 436 ? -66.093  -3.235  88.847  1.00 45.25  ? 496 HIS A N   1 
ATOM   3330  C CA  . HIS A 1 436 ? -67.163  -2.203  88.765  1.00 49.99  ? 496 HIS A CA  1 
ATOM   3331  C C   . HIS A 1 436 ? -68.562  -2.769  89.086  1.00 55.82  ? 496 HIS A C   1 
ATOM   3332  O O   . HIS A 1 436 ? -69.520  -1.975  89.091  1.00 57.13  ? 496 HIS A O   1 
ATOM   3333  C CB  . HIS A 1 436 ? -67.093  -1.507  87.417  1.00 51.88  ? 496 HIS A CB  1 
ATOM   3334  C CG  . HIS A 1 436 ? -65.952  -0.569  87.290  1.00 59.08  ? 496 HIS A CG  1 
ATOM   3335  N ND1 . HIS A 1 436 ? -64.670  -0.895  87.639  1.00 72.27  ? 496 HIS A ND1 1 
ATOM   3336  C CD2 . HIS A 1 436 ? -65.898  0.673   86.773  1.00 58.17  ? 496 HIS A CD2 1 
ATOM   3337  C CE1 . HIS A 1 436 ? -63.869  0.104   87.335  1.00 73.92  ? 496 HIS A CE1 1 
ATOM   3338  N NE2 . HIS A 1 436 ? -64.612  1.090   86.813  1.00 67.05  ? 496 HIS A NE2 1 
ATOM   3339  N N   . SER A 1 437 ? -68.688  -4.072  89.374  1.00 55.13  ? 497 SER A N   1 
ATOM   3340  C CA  . SER A 1 437 ? -69.920  -4.736  89.884  1.00 52.39  ? 497 SER A CA  1 
ATOM   3341  C C   . SER A 1 437 ? -70.455  -3.908  91.060  1.00 48.38  ? 497 SER A C   1 
ATOM   3342  O O   . SER A 1 437 ? -69.667  -3.585  91.978  1.00 50.09  ? 497 SER A O   1 
ATOM   3343  C CB  . SER A 1 437 ? -69.643  -6.200  90.302  1.00 55.17  ? 497 SER A CB  1 
ATOM   3344  O OG  . SER A 1 437 ? -70.791  -7.026  90.194  1.00 54.11  ? 497 SER A OG  1 
ATOM   3345  N N   . GLU A 1 438 ? -71.748  -3.591  91.045  1.00 48.50  ? 498 GLU A N   1 
ATOM   3346  C CA  . GLU A 1 438 ? -72.443  -2.808  92.103  1.00 52.72  ? 498 GLU A CA  1 
ATOM   3347  C C   . GLU A 1 438 ? -72.381  -3.548  93.454  1.00 47.72  ? 498 GLU A C   1 
ATOM   3348  O O   . GLU A 1 438 ? -72.426  -2.895  94.507  1.00 44.04  ? 498 GLU A O   1 
ATOM   3349  C CB  . GLU A 1 438 ? -73.873  -2.515  91.625  1.00 55.69  ? 498 GLU A CB  1 
ATOM   3350  C CG  . GLU A 1 438 ? -73.966  -1.463  90.513  1.00 55.74  ? 498 GLU A CG  1 
ATOM   3351  C CD  . GLU A 1 438 ? -73.911  -1.942  89.068  1.00 54.84  ? 498 GLU A CD  1 
ATOM   3352  O OE1 . GLU A 1 438 ? -73.859  -3.194  88.819  1.00 48.58  ? 498 GLU A OE1 1 
ATOM   3353  O OE2 . GLU A 1 438 ? -73.939  -1.053  88.180  1.00 49.08  ? 498 GLU A OE2 1 
ATOM   3354  N N   . CYS A 1 439 ? -72.328  -4.876  93.421  1.00 51.78  ? 499 CYS A N   1 
ATOM   3355  C CA  . CYS A 1 439 ? -71.978  -5.725  94.582  1.00 52.37  ? 499 CYS A CA  1 
ATOM   3356  C C   . CYS A 1 439 ? -71.446  -7.047  94.050  1.00 47.95  ? 499 CYS A C   1 
ATOM   3357  O O   . CYS A 1 439 ? -71.579  -7.257  92.851  1.00 49.75  ? 499 CYS A O   1 
ATOM   3358  C CB  . CYS A 1 439 ? -73.165  -5.929  95.521  1.00 54.92  ? 499 CYS A CB  1 
ATOM   3359  S SG  . CYS A 1 439 ? -74.581  -6.817  94.809  1.00 60.43  ? 499 CYS A SG  1 
ATOM   3360  N N   . THR A 1 440 ? -70.813  -7.838  94.914  1.00 51.23  ? 500 THR A N   1 
ATOM   3361  C CA  . THR A 1 440 ? -70.374  -9.234  94.655  1.00 53.08  ? 500 THR A CA  1 
ATOM   3362  C C   . THR A 1 440 ? -71.579  -10.164 94.857  1.00 51.34  ? 500 THR A C   1 
ATOM   3363  O O   . THR A 1 440 ? -72.562  -9.734  95.472  1.00 43.82  ? 500 THR A O   1 
ATOM   3364  C CB  . THR A 1 440 ? -69.220  -9.652  95.588  1.00 55.87  ? 500 THR A CB  1 
ATOM   3365  O OG1 . THR A 1 440 ? -69.699  -10.015 96.883  1.00 65.28  ? 500 THR A OG1 1 
ATOM   3366  C CG2 . THR A 1 440 ? -68.184  -8.575  95.785  1.00 57.74  ? 500 THR A CG2 1 
ATOM   3367  N N   . ALA A 1 441 ? -71.468  -11.412 94.417  1.00 56.95  ? 501 ALA A N   1 
ATOM   3368  C CA  . ALA A 1 441 ? -72.416  -12.504 94.762  1.00 56.89  ? 501 ALA A CA  1 
ATOM   3369  C C   . ALA A 1 441 ? -72.335  -12.807 96.263  1.00 53.58  ? 501 ALA A C   1 
ATOM   3370  O O   . ALA A 1 441 ? -73.387  -13.057 96.847  1.00 52.71  ? 501 ALA A O   1 
ATOM   3371  C CB  . ALA A 1 441 ? -72.116  -13.746 93.958  1.00 62.56  ? 501 ALA A CB  1 
ATOM   3372  N N   . GLU A 1 442 ? -71.137  -12.813 96.852  1.00 52.66  ? 502 GLU A N   1 
ATOM   3373  C CA  . GLU A 1 442 ? -70.995  -13.063 98.311  1.00 58.80  ? 502 GLU A CA  1 
ATOM   3374  C C   . GLU A 1 442 ? -71.739  -11.996 99.127  1.00 50.65  ? 502 GLU A C   1 
ATOM   3375  O O   . GLU A 1 442 ? -72.414  -12.400 100.079 1.00 38.87  ? 502 GLU A O   1 
ATOM   3376  C CB  . GLU A 1 442 ? -69.544  -13.216 98.776  1.00 69.24  ? 502 GLU A CB  1 
ATOM   3377  C CG  . GLU A 1 442 ? -69.373  -14.519 99.562  1.00 77.17  ? 502 GLU A CG  1 
ATOM   3378  C CD  . GLU A 1 442 ? -68.281  -14.687 100.596 1.00 85.28  ? 502 GLU A CD  1 
ATOM   3379  O OE1 . GLU A 1 442 ? -68.170  -15.831 101.110 1.00 90.15  ? 502 GLU A OE1 1 
ATOM   3380  O OE2 . GLU A 1 442 ? -67.587  -13.699 100.923 1.00 91.76  ? 502 GLU A OE2 1 
ATOM   3381  N N   . GLN A 1 443 ? -71.641  -10.708 98.778  1.00 45.84  ? 503 GLN A N   1 
ATOM   3382  C CA  . GLN A 1 443 ? -72.270  -9.596  99.549  1.00 50.01  ? 503 GLN A CA  1 
ATOM   3383  C C   . GLN A 1 443 ? -73.806  -9.737  99.517  1.00 61.60  ? 503 GLN A C   1 
ATOM   3384  O O   . GLN A 1 443 ? -74.448  -9.630  100.595 1.00 52.13  ? 503 GLN A O   1 
ATOM   3385  C CB  . GLN A 1 443 ? -71.842  -8.249  98.975  1.00 48.87  ? 503 GLN A CB  1 
ATOM   3386  C CG  . GLN A 1 443 ? -70.372  -7.951  99.183  1.00 52.28  ? 503 GLN A CG  1 
ATOM   3387  C CD  . GLN A 1 443 ? -69.917  -6.731  98.427  1.00 54.66  ? 503 GLN A CD  1 
ATOM   3388  O OE1 . GLN A 1 443 ? -70.562  -6.255  97.511  1.00 58.72  ? 503 GLN A OE1 1 
ATOM   3389  N NE2 . GLN A 1 443 ? -68.787  -6.197  98.836  1.00 65.78  ? 503 GLN A NE2 1 
ATOM   3390  N N   . ALA A 1 444 ? -74.360  -9.984  98.320  1.00 68.08  ? 504 ALA A N   1 
ATOM   3391  C CA  . ALA A 1 444 ? -75.810  -10.049 98.015  1.00 66.92  ? 504 ALA A CA  1 
ATOM   3392  C C   . ALA A 1 444 ? -76.496  -11.176 98.779  1.00 58.49  ? 504 ALA A C   1 
ATOM   3393  O O   . ALA A 1 444 ? -77.587  -10.911 99.304  1.00 73.90  ? 504 ALA A O   1 
ATOM   3394  C CB  . ALA A 1 444 ? -76.016  -10.249 96.540  1.00 73.42  ? 504 ALA A CB  1 
ATOM   3395  N N   . TYR A 1 445 ? -75.903  -12.373 98.803  1.00 51.43  ? 505 TYR A N   1 
ATOM   3396  C CA  . TYR A 1 445 ? -76.414  -13.547 99.565  1.00 56.53  ? 505 TYR A CA  1 
ATOM   3397  C C   . TYR A 1 445 ? -76.213  -13.382 101.092 1.00 62.03  ? 505 TYR A C   1 
ATOM   3398  O O   . TYR A 1 445 ? -77.102  -13.821 101.860 1.00 73.06  ? 505 TYR A O   1 
ATOM   3399  C CB  . TYR A 1 445 ? -75.821  -14.868 99.049  1.00 50.23  ? 505 TYR A CB  1 
ATOM   3400  C CG  . TYR A 1 445 ? -76.280  -15.256 97.665  1.00 55.88  ? 505 TYR A CG  1 
ATOM   3401  C CD1 . TYR A 1 445 ? -77.630  -15.361 97.335  1.00 49.09  ? 505 TYR A CD1 1 
ATOM   3402  C CD2 . TYR A 1 445 ? -75.345  -15.483 96.659  1.00 59.65  ? 505 TYR A CD2 1 
ATOM   3403  C CE1 . TYR A 1 445 ? -78.024  -15.630 96.035  1.00 49.23  ? 505 TYR A CE1 1 
ATOM   3404  C CE2 . TYR A 1 445 ? -75.733  -15.819 95.365  1.00 53.91  ? 505 TYR A CE2 1 
ATOM   3405  C CZ  . TYR A 1 445 ? -77.079  -15.860 95.046  1.00 47.72  ? 505 TYR A CZ  1 
ATOM   3406  O OH  . TYR A 1 445 ? -77.510  -16.136 93.785  1.00 47.08  ? 505 TYR A OH  1 
ATOM   3407  N N   . THR A 1 446 ? -75.114  -12.783 101.546 1.00 65.67  ? 506 THR A N   1 
ATOM   3408  C CA  . THR A 1 446 ? -74.854  -12.530 102.989 1.00 66.88  ? 506 THR A CA  1 
ATOM   3409  C C   . THR A 1 446 ? -75.801  -11.438 103.508 1.00 62.77  ? 506 THR A C   1 
ATOM   3410  O O   . THR A 1 446 ? -76.538  -11.736 104.461 1.00 66.37  ? 506 THR A O   1 
ATOM   3411  C CB  . THR A 1 446 ? -73.381  -12.184 103.241 1.00 65.11  ? 506 THR A CB  1 
ATOM   3412  O OG1 . THR A 1 446 ? -72.626  -13.083 102.441 1.00 57.06  ? 506 THR A OG1 1 
ATOM   3413  C CG2 . THR A 1 446 ? -72.950  -12.342 104.681 1.00 62.74  ? 506 THR A CG2 1 
ATOM   3414  N N   . TRP A 1 447 ? -75.811  -10.252 102.893 1.00 53.70  ? 507 TRP A N   1 
ATOM   3415  C CA  . TRP A 1 447 ? -76.548  -9.052  103.383 1.00 60.48  ? 507 TRP A CA  1 
ATOM   3416  C C   . TRP A 1 447 ? -78.075  -9.210  103.227 1.00 59.00  ? 507 TRP A C   1 
ATOM   3417  O O   . TRP A 1 447 ? -78.829  -8.320  103.727 1.00 58.71  ? 507 TRP A O   1 
ATOM   3418  C CB  . TRP A 1 447 ? -76.033  -7.800  102.651 1.00 64.37  ? 507 TRP A CB  1 
ATOM   3419  C CG  . TRP A 1 447 ? -74.585  -7.513  102.895 1.00 63.50  ? 507 TRP A CG  1 
ATOM   3420  C CD1 . TRP A 1 447 ? -73.820  -7.986  103.925 1.00 62.98  ? 507 TRP A CD1 1 
ATOM   3421  C CD2 . TRP A 1 447 ? -73.724  -6.674  102.099 1.00 71.80  ? 507 TRP A CD2 1 
ATOM   3422  N NE1 . TRP A 1 447 ? -72.543  -7.501  103.826 1.00 69.49  ? 507 TRP A NE1 1 
ATOM   3423  C CE2 . TRP A 1 447 ? -72.454  -6.680  102.727 1.00 71.76  ? 507 TRP A CE2 1 
ATOM   3424  C CE3 . TRP A 1 447 ? -73.892  -5.919  100.925 1.00 74.69  ? 507 TRP A CE3 1 
ATOM   3425  C CZ2 . TRP A 1 447 ? -71.374  -5.950  102.224 1.00 68.09  ? 507 TRP A CZ2 1 
ATOM   3426  C CZ3 . TRP A 1 447 ? -72.819  -5.203  100.424 1.00 70.95  ? 507 TRP A CZ3 1 
ATOM   3427  C CH2 . TRP A 1 447 ? -71.580  -5.223  101.068 1.00 69.87  ? 507 TRP A CH2 1 
ATOM   3428  N N   . SER A 1 448 ? -78.527  -10.275 102.550 1.00 55.41  ? 508 SER A N   1 
ATOM   3429  C CA  . SER A 1 448 ? -79.967  -10.586 102.336 1.00 54.49  ? 508 SER A CA  1 
ATOM   3430  C C   . SER A 1 448 ? -80.349  -11.904 103.010 1.00 52.37  ? 508 SER A C   1 
ATOM   3431  O O   . SER A 1 448 ? -81.436  -12.394 102.675 1.00 45.24  ? 508 SER A O   1 
ATOM   3432  C CB  . SER A 1 448 ? -80.295  -10.707 100.895 1.00 55.98  ? 508 SER A CB  1 
ATOM   3433  O OG  . SER A 1 448 ? -79.969  -12.035 100.457 1.00 52.33  ? 508 SER A OG  1 
ATOM   3434  N N   . GLN A 1 449 ? -79.485  -12.463 103.867 1.00 56.24  ? 509 GLN A N   1 
ATOM   3435  C CA  . GLN A 1 449 ? -79.693  -13.735 104.609 1.00 60.85  ? 509 GLN A CA  1 
ATOM   3436  C C   . GLN A 1 449 ? -80.106  -14.882 103.656 1.00 65.16  ? 509 GLN A C   1 
ATOM   3437  O O   . GLN A 1 449 ? -80.966  -15.706 104.030 1.00 59.73  ? 509 GLN A O   1 
ATOM   3438  C CB  . GLN A 1 449 ? -80.690  -13.497 105.742 1.00 65.82  ? 509 GLN A CB  1 
ATOM   3439  C CG  . GLN A 1 449 ? -80.230  -12.504 106.805 1.00 65.11  ? 509 GLN A CG  1 
ATOM   3440  C CD  . GLN A 1 449 ? -81.402  -11.829 107.473 1.00 72.77  ? 509 GLN A CD  1 
ATOM   3441  O OE1 . GLN A 1 449 ? -81.325  -10.673 107.864 1.00 82.83  ? 509 GLN A OE1 1 
ATOM   3442  N NE2 . GLN A 1 449 ? -82.528  -12.524 107.533 1.00 84.50  ? 509 GLN A NE2 1 
ATOM   3443  N N   . GLY A 1 450 ? -79.497  -14.963 102.466 1.00 59.39  ? 510 GLY A N   1 
ATOM   3444  C CA  . GLY A 1 450 ? -79.680  -16.073 101.511 1.00 53.74  ? 510 GLY A CA  1 
ATOM   3445  C C   . GLY A 1 450 ? -81.016  -15.994 100.775 1.00 52.56  ? 510 GLY A C   1 
ATOM   3446  O O   . GLY A 1 450 ? -81.427  -17.009 100.168 1.00 52.78  ? 510 GLY A O   1 
ATOM   3447  N N   . ARG A 1 451 ? -81.677  -14.835 100.780 1.00 49.56  ? 511 ARG A N   1 
ATOM   3448  C CA  . ARG A 1 451 ? -83.081  -14.704 100.315 1.00 55.38  ? 511 ARG A CA  1 
ATOM   3449  C C   . ARG A 1 451 ? -83.165  -13.936 98.983  1.00 52.10  ? 511 ARG A C   1 
ATOM   3450  O O   . ARG A 1 451 ? -84.256  -13.950 98.376  1.00 51.06  ? 511 ARG A O   1 
ATOM   3451  C CB  . ARG A 1 451 ? -83.944  -14.057 101.407 1.00 64.84  ? 511 ARG A CB  1 
ATOM   3452  C CG  . ARG A 1 451 ? -84.322  -14.996 102.551 1.00 57.19  ? 511 ARG A CG  1 
ATOM   3453  C CD  . ARG A 1 451 ? -85.068  -14.416 103.736 1.00 56.85  ? 511 ARG A CD  1 
ATOM   3454  N NE  . ARG A 1 451 ? -85.585  -13.065 103.507 1.00 60.97  ? 511 ARG A NE  1 
ATOM   3455  C CZ  . ARG A 1 451 ? -85.098  -11.921 104.005 1.00 58.82  ? 511 ARG A CZ  1 
ATOM   3456  N NH1 . ARG A 1 451 ? -84.055  -11.900 104.819 1.00 64.03  ? 511 ARG A NH1 1 
ATOM   3457  N NH2 . ARG A 1 451 ? -85.686  -10.798 103.661 1.00 54.72  ? 511 ARG A NH2 1 
ATOM   3458  N N   . SER A 1 452 ? -82.090  -13.284 98.540  1.00 55.61  ? 512 SER A N   1 
ATOM   3459  C CA  . SER A 1 452 ? -82.049  -12.534 97.253  1.00 54.79  ? 512 SER A CA  1 
ATOM   3460  C C   . SER A 1 452 ? -82.002  -13.513 96.076  1.00 52.73  ? 512 SER A C   1 
ATOM   3461  O O   . SER A 1 452 ? -81.416  -14.615 96.209  1.00 60.01  ? 512 SER A O   1 
ATOM   3462  C CB  . SER A 1 452 ? -80.894  -11.565 97.171  1.00 53.16  ? 512 SER A CB  1 
ATOM   3463  O OG  . SER A 1 452 ? -79.654  -12.268 97.167  1.00 52.54  ? 512 SER A OG  1 
ATOM   3464  N N   . ILE A 1 453 ? -82.675  -13.128 94.996  1.00 55.49  ? 513 ILE A N   1 
ATOM   3465  C CA  . ILE A 1 453 ? -82.490  -13.661 93.621  1.00 57.28  ? 513 ILE A CA  1 
ATOM   3466  C C   . ILE A 1 453 ? -81.476  -12.733 92.934  1.00 60.95  ? 513 ILE A C   1 
ATOM   3467  O O   . ILE A 1 453 ? -81.845  -11.550 92.603  1.00 59.54  ? 513 ILE A O   1 
ATOM   3468  C CB  . ILE A 1 453 ? -83.833  -13.712 92.877  1.00 55.21  ? 513 ILE A CB  1 
ATOM   3469  C CG1 . ILE A 1 453 ? -84.897  -14.516 93.632  1.00 55.06  ? 513 ILE A CG1 1 
ATOM   3470  C CG2 . ILE A 1 453 ? -83.609  -14.214 91.466  1.00 51.46  ? 513 ILE A CG2 1 
ATOM   3471  C CD1 . ILE A 1 453 ? -84.477  -15.904 94.035  1.00 53.40  ? 513 ILE A CD1 1 
ATOM   3472  N N   . PHE A 1 454 ? -80.239  -13.224 92.788  1.00 51.78  ? 514 PHE A N   1 
ATOM   3473  C CA  . PHE A 1 454 ? -79.077  -12.412 92.360  1.00 54.54  ? 514 PHE A CA  1 
ATOM   3474  C C   . PHE A 1 454 ? -78.602  -12.862 90.987  1.00 53.71  ? 514 PHE A C   1 
ATOM   3475  O O   . PHE A 1 454 ? -78.495  -14.073 90.713  1.00 65.49  ? 514 PHE A O   1 
ATOM   3476  C CB  . PHE A 1 454 ? -77.904  -12.518 93.340  1.00 57.91  ? 514 PHE A CB  1 
ATOM   3477  C CG  . PHE A 1 454 ? -76.752  -11.627 92.956  1.00 60.68  ? 514 PHE A CG  1 
ATOM   3478  C CD1 . PHE A 1 454 ? -76.903  -10.244 92.980  1.00 56.93  ? 514 PHE A CD1 1 
ATOM   3479  C CD2 . PHE A 1 454 ? -75.551  -12.164 92.502  1.00 58.86  ? 514 PHE A CD2 1 
ATOM   3480  C CE1 . PHE A 1 454 ? -75.851  -9.418  92.607  1.00 63.69  ? 514 PHE A CE1 1 
ATOM   3481  C CE2 . PHE A 1 454 ? -74.503  -11.334 92.135  1.00 61.54  ? 514 PHE A CE2 1 
ATOM   3482  C CZ  . PHE A 1 454 ? -74.652  -9.961  92.184  1.00 64.95  ? 514 PHE A CZ  1 
ATOM   3483  N N   . ALA A 1 455 ? -78.269  -11.878 90.163  1.00 57.47  ? 515 ALA A N   1 
ATOM   3484  C CA  . ALA A 1 455 ? -77.532  -12.075 88.900  1.00 56.94  ? 515 ALA A CA  1 
ATOM   3485  C C   . ALA A 1 455 ? -76.712  -10.817 88.608  1.00 51.96  ? 515 ALA A C   1 
ATOM   3486  O O   . ALA A 1 455 ? -77.078  -9.739  89.127  1.00 45.50  ? 515 ALA A O   1 
ATOM   3487  C CB  . ALA A 1 455 ? -78.511  -12.399 87.811  1.00 60.05  ? 515 ALA A CB  1 
ATOM   3488  N N   . SER A 1 456 ? -75.641  -10.973 87.825  1.00 52.30  ? 516 SER A N   1 
ATOM   3489  C CA  . SER A 1 456 ? -74.602  -9.943  87.584  1.00 58.47  ? 516 SER A CA  1 
ATOM   3490  C C   . SER A 1 456 ? -74.071  -10.057 86.164  1.00 54.11  ? 516 SER A C   1 
ATOM   3491  O O   . SER A 1 456 ? -74.262  -11.132 85.559  1.00 48.27  ? 516 SER A O   1 
ATOM   3492  C CB  . SER A 1 456 ? -73.465  -10.065 88.581  1.00 69.59  ? 516 SER A CB  1 
ATOM   3493  O OG  . SER A 1 456 ? -72.739  -11.293 88.429  1.00 59.11  ? 516 SER A OG  1 
ATOM   3494  N N   . GLY A 1 457 ? -73.385  -9.003  85.707  1.00 56.83  ? 517 GLY A N   1 
ATOM   3495  C CA  . GLY A 1 457 ? -72.745  -8.943  84.380  1.00 58.67  ? 517 GLY A CA  1 
ATOM   3496  C C   . GLY A 1 457 ? -71.495  -9.826  84.271  1.00 58.64  ? 517 GLY A C   1 
ATOM   3497  O O   . GLY A 1 457 ? -71.296  -10.487 83.194  1.00 47.79  ? 517 GLY A O   1 
ATOM   3498  N N   . SER A 1 458 ? -70.653  -9.819  85.310  1.00 50.85  ? 518 SER A N   1 
ATOM   3499  C CA  . SER A 1 458 ? -69.346  -10.517 85.290  1.00 49.60  ? 518 SER A CA  1 
ATOM   3500  C C   . SER A 1 458 ? -69.438  -11.788 86.128  1.00 50.65  ? 518 SER A C   1 
ATOM   3501  O O   . SER A 1 458 ? -70.169  -11.809 87.101  1.00 49.16  ? 518 SER A O   1 
ATOM   3502  C CB  . SER A 1 458 ? -68.292  -9.568  85.765  1.00 50.55  ? 518 SER A CB  1 
ATOM   3503  O OG  . SER A 1 458 ? -68.269  -8.431  84.918  1.00 52.53  ? 518 SER A OG  1 
ATOM   3504  N N   . PRO A 1 459 ? -68.722  -12.889 85.808  1.00 56.61  ? 519 PRO A N   1 
ATOM   3505  C CA  . PRO A 1 459 ? -68.902  -14.165 86.513  1.00 60.62  ? 519 PRO A CA  1 
ATOM   3506  C C   . PRO A 1 459 ? -68.387  -14.092 87.957  1.00 58.31  ? 519 PRO A C   1 
ATOM   3507  O O   . PRO A 1 459 ? -67.443  -13.374 88.153  1.00 57.47  ? 519 PRO A O   1 
ATOM   3508  C CB  . PRO A 1 459 ? -68.086  -15.171 85.695  1.00 56.87  ? 519 PRO A CB  1 
ATOM   3509  C CG  . PRO A 1 459 ? -67.025  -14.307 85.088  1.00 63.11  ? 519 PRO A CG  1 
ATOM   3510  C CD  . PRO A 1 459 ? -67.679  -12.972 84.791  1.00 56.10  ? 519 PRO A CD  1 
ATOM   3511  N N   . PHE A 1 460 ? -69.073  -14.768 88.895  1.00 56.13  ? 520 PHE A N   1 
ATOM   3512  C CA  . PHE A 1 460 ? -68.728  -14.948 90.335  1.00 49.76  ? 520 PHE A CA  1 
ATOM   3513  C C   . PHE A 1 460 ? -68.830  -16.425 90.723  1.00 49.12  ? 520 PHE A C   1 
ATOM   3514  O O   . PHE A 1 460 ? -69.751  -17.118 90.289  1.00 49.32  ? 520 PHE A O   1 
ATOM   3515  C CB  . PHE A 1 460 ? -69.694  -14.184 91.233  1.00 44.50  ? 520 PHE A CB  1 
ATOM   3516  C CG  . PHE A 1 460 ? -69.451  -12.706 91.282  1.00 42.40  ? 520 PHE A CG  1 
ATOM   3517  C CD1 . PHE A 1 460 ? -68.400  -12.191 92.015  1.00 43.87  ? 520 PHE A CD1 1 
ATOM   3518  C CD2 . PHE A 1 460 ? -70.289  -11.826 90.605  1.00 45.99  ? 520 PHE A CD2 1 
ATOM   3519  C CE1 . PHE A 1 460 ? -68.179  -10.822 92.060  1.00 50.40  ? 520 PHE A CE1 1 
ATOM   3520  C CE2 . PHE A 1 460 ? -70.097  -10.452 90.671  1.00 43.26  ? 520 PHE A CE2 1 
ATOM   3521  C CZ  . PHE A 1 460 ? -69.028  -9.951  91.392  1.00 50.69  ? 520 PHE A CZ  1 
ATOM   3522  N N   . ALA A 1 461 ? -67.919  -16.910 91.543  1.00 49.60  ? 521 ALA A N   1 
ATOM   3523  C CA  . ALA A 1 461 ? -67.933  -18.337 91.912  1.00 59.61  ? 521 ALA A CA  1 
ATOM   3524  C C   . ALA A 1 461 ? -69.179  -18.580 92.758  1.00 63.85  ? 521 ALA A C   1 
ATOM   3525  O O   . ALA A 1 461 ? -69.747  -17.630 93.315  1.00 55.50  ? 521 ALA A O   1 
ATOM   3526  C CB  . ALA A 1 461 ? -66.664  -18.716 92.633  1.00 66.27  ? 521 ALA A CB  1 
ATOM   3527  N N   . PRO A 1 462 ? -69.623  -19.859 92.850  1.00 63.50  ? 522 PRO A N   1 
ATOM   3528  C CA  . PRO A 1 462 ? -70.675  -20.251 93.788  1.00 58.91  ? 522 PRO A CA  1 
ATOM   3529  C C   . PRO A 1 462 ? -70.383  -19.709 95.196  1.00 57.22  ? 522 PRO A C   1 
ATOM   3530  O O   . PRO A 1 462 ? -69.237  -19.635 95.550  1.00 58.87  ? 522 PRO A O   1 
ATOM   3531  C CB  . PRO A 1 462 ? -70.642  -21.790 93.756  1.00 59.64  ? 522 PRO A CB  1 
ATOM   3532  C CG  . PRO A 1 462 ? -70.110  -22.114 92.377  1.00 58.66  ? 522 PRO A CG  1 
ATOM   3533  C CD  . PRO A 1 462 ? -69.138  -20.994 92.043  1.00 60.81  ? 522 PRO A CD  1 
ATOM   3534  N N   . VAL A 1 463 ? -71.429  -19.331 95.933  1.00 57.01  ? 523 VAL A N   1 
ATOM   3535  C CA  . VAL A 1 463 ? -71.389  -18.683 97.285  1.00 59.05  ? 523 VAL A CA  1 
ATOM   3536  C C   . VAL A 1 463 ? -72.029  -19.678 98.266  1.00 62.68  ? 523 VAL A C   1 
ATOM   3537  O O   . VAL A 1 463 ? -73.137  -20.153 97.960  1.00 73.68  ? 523 VAL A O   1 
ATOM   3538  C CB  . VAL A 1 463 ? -72.102  -17.299 97.319  1.00 48.43  ? 523 VAL A CB  1 
ATOM   3539  C CG1 . VAL A 1 463 ? -72.081  -16.720 98.730  1.00 44.05  ? 523 VAL A CG1 1 
ATOM   3540  C CG2 . VAL A 1 463 ? -71.539  -16.296 96.328  1.00 43.83  ? 523 VAL A CG2 1 
ATOM   3541  N N   . GLU A 1 464 ? -71.367  -20.003 99.384  1.00 65.13  ? 524 GLU A N   1 
ATOM   3542  C CA  . GLU A 1 464 ? -71.936  -20.879 100.448 1.00 65.64  ? 524 GLU A CA  1 
ATOM   3543  C C   . GLU A 1 464 ? -72.392  -20.008 101.630 1.00 65.73  ? 524 GLU A C   1 
ATOM   3544  O O   . GLU A 1 464 ? -71.622  -19.149 102.040 1.00 62.37  ? 524 GLU A O   1 
ATOM   3545  C CB  . GLU A 1 464 ? -71.008  -22.050 100.806 1.00 70.74  ? 524 GLU A CB  1 
ATOM   3546  C CG  . GLU A 1 464 ? -69.637  -21.705 101.378 1.00 94.67  ? 524 GLU A CG  1 
ATOM   3547  C CD  . GLU A 1 464 ? -68.612  -22.841 101.317 1.00 106.98 ? 524 GLU A CD  1 
ATOM   3548  O OE1 . GLU A 1 464 ? -68.579  -23.569 100.280 1.00 77.84  ? 524 GLU A OE1 1 
ATOM   3549  O OE2 . GLU A 1 464 ? -67.832  -23.007 102.314 1.00 111.29 ? 524 GLU A OE2 1 
ATOM   3550  N N   . TYR A 1 465 ? -73.622  -20.239 102.122 1.00 71.44  ? 525 TYR A N   1 
ATOM   3551  C CA  . TYR A 1 465 ? -74.314  -19.465 103.189 1.00 64.72  ? 525 TYR A CA  1 
ATOM   3552  C C   . TYR A 1 465 ? -75.319  -20.371 103.922 1.00 65.17  ? 525 TYR A C   1 
ATOM   3553  O O   . TYR A 1 465 ? -76.266  -20.871 103.303 1.00 62.10  ? 525 TYR A O   1 
ATOM   3554  C CB  . TYR A 1 465 ? -75.012  -18.251 102.581 1.00 56.48  ? 525 TYR A CB  1 
ATOM   3555  C CG  . TYR A 1 465 ? -75.575  -17.307 103.597 1.00 56.54  ? 525 TYR A CG  1 
ATOM   3556  C CD1 . TYR A 1 465 ? -74.782  -16.301 104.109 1.00 60.70  ? 525 TYR A CD1 1 
ATOM   3557  C CD2 . TYR A 1 465 ? -76.876  -17.438 104.063 1.00 59.69  ? 525 TYR A CD2 1 
ATOM   3558  C CE1 . TYR A 1 465 ? -75.277  -15.417 105.056 1.00 72.13  ? 525 TYR A CE1 1 
ATOM   3559  C CE2 . TYR A 1 465 ? -77.384  -16.563 105.009 1.00 71.05  ? 525 TYR A CE2 1 
ATOM   3560  C CZ  . TYR A 1 465 ? -76.581  -15.549 105.512 1.00 78.27  ? 525 TYR A CZ  1 
ATOM   3561  O OH  . TYR A 1 465 ? -77.060  -14.662 106.439 1.00 79.77  ? 525 TYR A OH  1 
ATOM   3562  N N   . GLU A 1 466 ? -75.101  -20.571 105.223 1.00 76.11  ? 526 GLU A N   1 
ATOM   3563  C CA  . GLU A 1 466 ? -75.868  -21.473 106.131 1.00 75.26  ? 526 GLU A CA  1 
ATOM   3564  C C   . GLU A 1 466 ? -76.102  -22.835 105.464 1.00 67.20  ? 526 GLU A C   1 
ATOM   3565  O O   . GLU A 1 466 ? -77.241  -23.275 105.369 1.00 68.34  ? 526 GLU A O   1 
ATOM   3566  C CB  . GLU A 1 466 ? -77.132  -20.756 106.589 1.00 77.56  ? 526 GLU A CB  1 
ATOM   3567  C CG  . GLU A 1 466 ? -76.826  -19.699 107.638 1.00 92.48  ? 526 GLU A CG  1 
ATOM   3568  C CD  . GLU A 1 466 ? -77.632  -18.405 107.587 1.00 90.55  ? 526 GLU A CD  1 
ATOM   3569  O OE1 . GLU A 1 466 ? -78.686  -18.350 106.941 1.00 101.75 ? 526 GLU A OE1 1 
ATOM   3570  O OE2 . GLU A 1 466 ? -77.224  -17.456 108.235 1.00 90.62  ? 526 GLU A OE2 1 
ATOM   3571  N N   . GLY A 1 467 ? -75.026  -23.477 105.019 1.00 62.07  ? 527 GLY A N   1 
ATOM   3572  C CA  . GLY A 1 467 ? -74.997  -24.901 104.651 1.00 63.56  ? 527 GLY A CA  1 
ATOM   3573  C C   . GLY A 1 467 ? -75.662  -25.162 103.327 1.00 61.93  ? 527 GLY A C   1 
ATOM   3574  O O   . GLY A 1 467 ? -75.951  -26.338 103.062 1.00 62.16  ? 527 GLY A O   1 
ATOM   3575  N N   . LYS A 1 468 ? -75.839  -24.115 102.521 1.00 78.65  ? 528 LYS A N   1 
ATOM   3576  C CA  . LYS A 1 468 ? -76.457  -24.175 101.169 1.00 88.71  ? 528 LYS A CA  1 
ATOM   3577  C C   . LYS A 1 468 ? -75.523  -23.502 100.143 1.00 80.86  ? 528 LYS A C   1 
ATOM   3578  O O   . LYS A 1 468 ? -74.778  -22.592 100.535 1.00 84.69  ? 528 LYS A O   1 
ATOM   3579  C CB  . LYS A 1 468 ? -77.846  -23.528 101.250 1.00 97.55  ? 528 LYS A CB  1 
ATOM   3580  C CG  . LYS A 1 468 ? -78.993  -24.417 100.782 1.00 107.46 ? 528 LYS A CG  1 
ATOM   3581  C CD  . LYS A 1 468 ? -79.261  -25.646 101.676 1.00 105.17 ? 528 LYS A CD  1 
ATOM   3582  C CE  . LYS A 1 468 ? -80.142  -25.366 102.883 1.00 115.77 ? 528 LYS A CE  1 
ATOM   3583  N NZ  . LYS A 1 468 ? -80.561  -26.611 103.577 1.00 111.55 ? 528 LYS A NZ  1 
ATOM   3584  N N   . THR A 1 469 ? -75.554  -23.944 98.879  1.00 76.49  ? 529 THR A N   1 
ATOM   3585  C CA  . THR A 1 469 ? -74.756  -23.406 97.728  1.00 72.66  ? 529 THR A CA  1 
ATOM   3586  C C   . THR A 1 469 ? -75.641  -22.545 96.805  1.00 62.72  ? 529 THR A C   1 
ATOM   3587  O O   . THR A 1 469 ? -76.657  -23.042 96.334  1.00 61.55  ? 529 THR A O   1 
ATOM   3588  C CB  . THR A 1 469 ? -74.095  -24.537 96.928  1.00 69.18  ? 529 THR A CB  1 
ATOM   3589  O OG1 . THR A 1 469 ? -73.259  -25.272 97.820  1.00 71.65  ? 529 THR A OG1 1 
ATOM   3590  C CG2 . THR A 1 469 ? -73.250  -24.042 95.772  1.00 67.52  ? 529 THR A CG2 1 
ATOM   3591  N N   . PHE A 1 470 ? -75.254  -21.297 96.546  1.00 52.93  ? 530 PHE A N   1 
ATOM   3592  C CA  . PHE A 1 470 ? -75.922  -20.370 95.596  1.00 50.80  ? 530 PHE A CA  1 
ATOM   3593  C C   . PHE A 1 470 ? -75.023  -20.171 94.370  1.00 54.52  ? 530 PHE A C   1 
ATOM   3594  O O   . PHE A 1 470 ? -73.895  -19.690 94.528  1.00 76.60  ? 530 PHE A O   1 
ATOM   3595  C CB  . PHE A 1 470 ? -76.236  -19.041 96.282  1.00 50.34  ? 530 PHE A CB  1 
ATOM   3596  C CG  . PHE A 1 470 ? -77.236  -19.157 97.400  1.00 60.71  ? 530 PHE A CG  1 
ATOM   3597  C CD1 . PHE A 1 470 ? -76.939  -19.878 98.540  1.00 67.48  ? 530 PHE A CD1 1 
ATOM   3598  C CD2 . PHE A 1 470 ? -78.473  -18.542 97.313  1.00 65.38  ? 530 PHE A CD2 1 
ATOM   3599  C CE1 . PHE A 1 470 ? -77.868  -20.008 99.558  1.00 72.40  ? 530 PHE A CE1 1 
ATOM   3600  C CE2 . PHE A 1 470 ? -79.402  -18.675 98.328  1.00 68.04  ? 530 PHE A CE2 1 
ATOM   3601  C CZ  . PHE A 1 470 ? -79.103  -19.417 99.446  1.00 74.86  ? 530 PHE A CZ  1 
ATOM   3602  N N   . VAL A 1 471 ? -75.501  -20.557 93.187  1.00 53.60  ? 531 VAL A N   1 
ATOM   3603  C CA  . VAL A 1 471 ? -74.823  -20.359 91.873  1.00 46.80  ? 531 VAL A CA  1 
ATOM   3604  C C   . VAL A 1 471 ? -75.443  -19.141 91.201  1.00 49.10  ? 531 VAL A C   1 
ATOM   3605  O O   . VAL A 1 471 ? -76.463  -19.263 90.543  1.00 49.96  ? 531 VAL A O   1 
ATOM   3606  C CB  . VAL A 1 471 ? -75.016  -21.603 90.996  1.00 45.30  ? 531 VAL A CB  1 
ATOM   3607  C CG1 . VAL A 1 471 ? -74.284  -21.429 89.686  1.00 57.08  ? 531 VAL A CG1 1 
ATOM   3608  C CG2 . VAL A 1 471 ? -74.581  -22.868 91.696  1.00 41.65  ? 531 VAL A CG2 1 
ATOM   3609  N N   . PRO A 1 472 ? -74.907  -17.916 91.362  1.00 51.27  ? 532 PRO A N   1 
ATOM   3610  C CA  . PRO A 1 472 ? -75.575  -16.721 90.844  1.00 52.71  ? 532 PRO A CA  1 
ATOM   3611  C C   . PRO A 1 472 ? -75.558  -16.788 89.319  1.00 50.72  ? 532 PRO A C   1 
ATOM   3612  O O   . PRO A 1 472 ? -74.578  -17.208 88.812  1.00 47.15  ? 532 PRO A O   1 
ATOM   3613  C CB  . PRO A 1 472 ? -74.749  -15.553 91.383  1.00 50.03  ? 532 PRO A CB  1 
ATOM   3614  C CG  . PRO A 1 472 ? -73.387  -16.162 91.597  1.00 49.80  ? 532 PRO A CG  1 
ATOM   3615  C CD  . PRO A 1 472 ? -73.645  -17.597 92.015  1.00 51.20  ? 532 PRO A CD  1 
ATOM   3616  N N   . GLY A 1 473 ? -76.662  -16.471 88.653  1.00 52.56  ? 533 GLY A N   1 
ATOM   3617  C CA  . GLY A 1 473 ? -76.715  -16.495 87.176  1.00 54.74  ? 533 GLY A CA  1 
ATOM   3618  C C   . GLY A 1 473 ? -75.977  -15.296 86.594  1.00 56.67  ? 533 GLY A C   1 
ATOM   3619  O O   . GLY A 1 473 ? -75.825  -14.266 87.343  1.00 49.16  ? 533 GLY A O   1 
ATOM   3620  N N   . GLN A 1 474 ? -75.522  -15.408 85.334  1.00 53.17  ? 534 GLN A N   1 
ATOM   3621  C CA  . GLN A 1 474 ? -74.825  -14.292 84.633  1.00 58.74  ? 534 GLN A CA  1 
ATOM   3622  C C   . GLN A 1 474 ? -75.783  -13.590 83.647  1.00 58.96  ? 534 GLN A C   1 
ATOM   3623  O O   . GLN A 1 474 ? -76.042  -14.095 82.533  1.00 57.75  ? 534 GLN A O   1 
ATOM   3624  C CB  . GLN A 1 474 ? -73.536  -14.766 83.960  1.00 69.19  ? 534 GLN A CB  1 
ATOM   3625  C CG  . GLN A 1 474 ? -72.472  -13.668 83.905  1.00 67.32  ? 534 GLN A CG  1 
ATOM   3626  C CD  . GLN A 1 474 ? -71.209  -14.118 83.209  1.00 58.94  ? 534 GLN A CD  1 
ATOM   3627  O OE1 . GLN A 1 474 ? -70.836  -15.301 83.248  1.00 49.95  ? 534 GLN A OE1 1 
ATOM   3628  N NE2 . GLN A 1 474 ? -70.551  -13.154 82.574  1.00 51.60  ? 534 GLN A NE2 1 
ATOM   3629  N N   . SER A 1 475 ? -76.294  -12.441 84.060  1.00 48.66  ? 535 SER A N   1 
ATOM   3630  C CA  . SER A 1 475 ? -77.212  -11.597 83.273  1.00 44.04  ? 535 SER A CA  1 
ATOM   3631  C C   . SER A 1 475 ? -76.358  -10.671 82.415  1.00 47.01  ? 535 SER A C   1 
ATOM   3632  O O   . SER A 1 475 ? -76.215  -9.470  82.759  1.00 47.54  ? 535 SER A O   1 
ATOM   3633  C CB  . SER A 1 475 ? -78.101  -10.856 84.197  1.00 48.59  ? 535 SER A CB  1 
ATOM   3634  O OG  . SER A 1 475 ? -78.788  -9.824  83.535  1.00 46.91  ? 535 SER A OG  1 
ATOM   3635  N N   . ASN A 1 476 ? -75.771  -11.253 81.369  1.00 50.23  ? 536 ASN A N   1 
ATOM   3636  C CA  . ASN A 1 476 ? -74.862  -10.606 80.378  1.00 49.68  ? 536 ASN A CA  1 
ATOM   3637  C C   . ASN A 1 476 ? -75.399  -10.887 78.963  1.00 51.61  ? 536 ASN A C   1 
ATOM   3638  O O   . ASN A 1 476 ? -75.828  -12.048 78.681  1.00 49.83  ? 536 ASN A O   1 
ATOM   3639  C CB  . ASN A 1 476 ? -73.424  -11.120 80.528  1.00 51.00  ? 536 ASN A CB  1 
ATOM   3640  C CG  . ASN A 1 476 ? -72.403  -10.329 79.737  1.00 52.09  ? 536 ASN A CG  1 
ATOM   3641  O OD1 . ASN A 1 476 ? -72.324  -10.438 78.513  1.00 56.94  ? 536 ASN A OD1 1 
ATOM   3642  N ND2 . ASN A 1 476 ? -71.576  -9.570  80.432  1.00 56.28  ? 536 ASN A ND2 1 
ATOM   3643  N N   . ASN A 1 477 ? -75.349  -9.887  78.079  1.00 51.92  ? 537 ASN A N   1 
ATOM   3644  C CA  . ASN A 1 477 ? -76.050  -9.949  76.770  1.00 57.42  ? 537 ASN A CA  1 
ATOM   3645  C C   . ASN A 1 477 ? -75.469  -11.072 75.886  1.00 55.71  ? 537 ASN A C   1 
ATOM   3646  O O   . ASN A 1 477 ? -76.051  -11.335 74.829  1.00 54.36  ? 537 ASN A O   1 
ATOM   3647  C CB  . ASN A 1 477 ? -76.075  -8.575  76.097  1.00 60.12  ? 537 ASN A CB  1 
ATOM   3648  C CG  . ASN A 1 477 ? -74.703  -7.968  75.957  1.00 61.40  ? 537 ASN A CG  1 
ATOM   3649  O OD1 . ASN A 1 477 ? -73.729  -8.671  75.684  1.00 55.92  ? 537 ASN A OD1 1 
ATOM   3650  N ND2 . ASN A 1 477 ? -74.631  -6.663  76.148  1.00 72.31  ? 537 ASN A ND2 1 
ATOM   3651  N N   . ALA A 1 478 ? -74.376  -11.715 76.305  1.00 55.95  ? 538 ALA A N   1 
ATOM   3652  C CA  . ALA A 1 478 ? -73.732  -12.863 75.615  1.00 56.28  ? 538 ALA A CA  1 
ATOM   3653  C C   . ALA A 1 478 ? -74.654  -14.092 75.549  1.00 57.32  ? 538 ALA A C   1 
ATOM   3654  O O   . ALA A 1 478 ? -74.371  -14.978 74.758  1.00 45.92  ? 538 ALA A O   1 
ATOM   3655  C CB  . ALA A 1 478 ? -72.461  -13.206 76.323  1.00 59.61  ? 538 ALA A CB  1 
ATOM   3656  N N   . TYR A 1 479 ? -75.677  -14.175 76.392  1.00 59.99  ? 539 TYR A N   1 
ATOM   3657  C CA  . TYR A 1 479 ? -76.741  -15.218 76.339  1.00 62.82  ? 539 TYR A CA  1 
ATOM   3658  C C   . TYR A 1 479 ? -77.730  -14.960 75.170  1.00 60.89  ? 539 TYR A C   1 
ATOM   3659  O O   . TYR A 1 479 ? -78.376  -15.915 74.683  1.00 56.23  ? 539 TYR A O   1 
ATOM   3660  C CB  . TYR A 1 479 ? -77.482  -15.221 77.685  1.00 62.50  ? 539 TYR A CB  1 
ATOM   3661  C CG  . TYR A 1 479 ? -76.980  -16.197 78.725  1.00 63.81  ? 539 TYR A CG  1 
ATOM   3662  C CD1 . TYR A 1 479 ? -77.135  -17.561 78.524  1.00 66.02  ? 539 TYR A CD1 1 
ATOM   3663  C CD2 . TYR A 1 479 ? -76.395  -15.783 79.921  1.00 60.10  ? 539 TYR A CD2 1 
ATOM   3664  C CE1 . TYR A 1 479 ? -76.740  -18.487 79.480  1.00 65.53  ? 539 TYR A CE1 1 
ATOM   3665  C CE2 . TYR A 1 479 ? -75.990  -16.704 80.886  1.00 58.32  ? 539 TYR A CE2 1 
ATOM   3666  C CZ  . TYR A 1 479 ? -76.166  -18.064 80.667  1.00 58.28  ? 539 TYR A CZ  1 
ATOM   3667  O OH  . TYR A 1 479 ? -75.771  -19.028 81.551  1.00 48.84  ? 539 TYR A OH  1 
ATOM   3668  N N   . ILE A 1 480 ? -77.853  -13.693 74.732  1.00 60.05  ? 540 ILE A N   1 
ATOM   3669  C CA  . ILE A 1 480 ? -78.905  -13.179 73.800  1.00 61.22  ? 540 ILE A CA  1 
ATOM   3670  C C   . ILE A 1 480 ? -78.312  -12.987 72.389  1.00 65.89  ? 540 ILE A C   1 
ATOM   3671  O O   . ILE A 1 480 ? -78.885  -13.607 71.463  1.00 61.92  ? 540 ILE A O   1 
ATOM   3672  C CB  . ILE A 1 480 ? -79.552  -11.872 74.339  1.00 62.84  ? 540 ILE A CB  1 
ATOM   3673  C CG1 . ILE A 1 480 ? -80.440  -12.112 75.567  1.00 63.38  ? 540 ILE A CG1 1 
ATOM   3674  C CG2 . ILE A 1 480 ? -80.324  -11.135 73.252  1.00 61.16  ? 540 ILE A CG2 1 
ATOM   3675  C CD1 . ILE A 1 480 ? -81.701  -12.905 75.320  1.00 60.52  ? 540 ILE A CD1 1 
ATOM   3676  N N   . PHE A 1 481 ? -77.255  -12.157 72.208  1.00 56.69  ? 541 PHE A N   1 
ATOM   3677  C CA  . PHE A 1 481 ? -76.847  -11.635 70.872  1.00 47.23  ? 541 PHE A CA  1 
ATOM   3678  C C   . PHE A 1 481 ? -76.387  -12.790 69.980  1.00 40.38  ? 541 PHE A C   1 
ATOM   3679  O O   . PHE A 1 481 ? -76.662  -12.748 68.787  1.00 43.09  ? 541 PHE A O   1 
ATOM   3680  C CB  . PHE A 1 481 ? -75.881  -10.445 70.941  1.00 43.60  ? 541 PHE A CB  1 
ATOM   3681  C CG  . PHE A 1 481 ? -74.470  -10.763 71.360  1.00 43.76  ? 541 PHE A CG  1 
ATOM   3682  C CD1 . PHE A 1 481 ? -73.634  -11.497 70.543  1.00 43.53  ? 541 PHE A CD1 1 
ATOM   3683  C CD2 . PHE A 1 481 ? -73.974  -10.361 72.592  1.00 49.09  ? 541 PHE A CD2 1 
ATOM   3684  C CE1 . PHE A 1 481 ? -72.347  -11.829 70.951  1.00 44.14  ? 541 PHE A CE1 1 
ATOM   3685  C CE2 . PHE A 1 481 ? -72.682  -10.683 72.990  1.00 46.28  ? 541 PHE A CE2 1 
ATOM   3686  C CZ  . PHE A 1 481 ? -71.863  -11.408 72.167  1.00 39.80  ? 541 PHE A CZ  1 
ATOM   3687  N N   . PRO A 1 482 ? -75.694  -13.845 70.458  1.00 37.62  ? 542 PRO A N   1 
ATOM   3688  C CA  . PRO A 1 482 ? -75.348  -14.987 69.602  1.00 44.30  ? 542 PRO A CA  1 
ATOM   3689  C C   . PRO A 1 482 ? -76.569  -15.626 68.925  1.00 45.03  ? 542 PRO A C   1 
ATOM   3690  O O   . PRO A 1 482 ? -76.523  -15.784 67.733  1.00 44.40  ? 542 PRO A O   1 
ATOM   3691  C CB  . PRO A 1 482 ? -74.659  -15.999 70.515  1.00 39.69  ? 542 PRO A CB  1 
ATOM   3692  C CG  . PRO A 1 482 ? -74.073  -15.100 71.569  1.00 44.03  ? 542 PRO A CG  1 
ATOM   3693  C CD  . PRO A 1 482 ? -75.112  -13.998 71.785  1.00 40.47  ? 542 PRO A CD  1 
ATOM   3694  N N   . GLY A 1 483 ? -77.610  -15.963 69.688  1.00 42.88  ? 543 GLY A N   1 
ATOM   3695  C CA  . GLY A 1 483 ? -78.898  -16.430 69.137  1.00 37.65  ? 543 GLY A CA  1 
ATOM   3696  C C   . GLY A 1 483 ? -79.614  -15.383 68.284  1.00 38.88  ? 543 GLY A C   1 
ATOM   3697  O O   . GLY A 1 483 ? -80.147  -15.723 67.214  1.00 41.47  ? 543 GLY A O   1 
ATOM   3698  N N   . LEU A 1 484 ? -79.679  -14.136 68.741  1.00 43.25  ? 544 LEU A N   1 
ATOM   3699  C CA  . LEU A 1 484 ? -80.435  -13.047 68.065  1.00 41.47  ? 544 LEU A CA  1 
ATOM   3700  C C   . LEU A 1 484 ? -79.766  -12.732 66.739  1.00 44.33  ? 544 LEU A C   1 
ATOM   3701  O O   . LEU A 1 484 ? -80.491  -12.505 65.748  1.00 49.57  ? 544 LEU A O   1 
ATOM   3702  C CB  . LEU A 1 484 ? -80.490  -11.804 68.958  1.00 42.89  ? 544 LEU A CB  1 
ATOM   3703  C CG  . LEU A 1 484 ? -81.128  -10.573 68.331  1.00 42.15  ? 544 LEU A CG  1 
ATOM   3704  C CD1 . LEU A 1 484 ? -82.190  -10.002 69.232  1.00 44.67  ? 544 LEU A CD1 1 
ATOM   3705  C CD2 . LEU A 1 484 ? -80.084  -9.527  68.028  1.00 46.29  ? 544 LEU A CD2 1 
ATOM   3706  N N   . GLY A 1 485 ? -78.430  -12.703 66.707  1.00 49.20  ? 545 GLY A N   1 
ATOM   3707  C CA  . GLY A 1 485 ? -77.666  -12.454 65.459  1.00 45.98  ? 545 GLY A CA  1 
ATOM   3708  C C   . GLY A 1 485 ? -77.918  -13.560 64.443  1.00 43.74  ? 545 GLY A C   1 
ATOM   3709  O O   . GLY A 1 485 ? -78.349  -13.222 63.346  1.00 40.82  ? 545 GLY A O   1 
ATOM   3710  N N   . LEU A 1 486 ? -77.684  -14.832 64.822  1.00 46.57  ? 546 LEU A N   1 
ATOM   3711  C CA  . LEU A 1 486 ? -77.902  -16.055 63.994  1.00 41.96  ? 546 LEU A CA  1 
ATOM   3712  C C   . LEU A 1 486 ? -79.304  -15.987 63.412  1.00 42.87  ? 546 LEU A C   1 
ATOM   3713  O O   . LEU A 1 486 ? -79.462  -16.289 62.220  1.00 48.33  ? 546 LEU A O   1 
ATOM   3714  C CB  . LEU A 1 486 ? -77.765  -17.326 64.845  1.00 43.39  ? 546 LEU A CB  1 
ATOM   3715  C CG  . LEU A 1 486 ? -77.951  -18.646 64.097  1.00 45.87  ? 546 LEU A CG  1 
ATOM   3716  C CD1 . LEU A 1 486 ? -76.861  -18.822 63.059  1.00 50.44  ? 546 LEU A CD1 1 
ATOM   3717  C CD2 . LEU A 1 486 ? -77.935  -19.853 65.019  1.00 42.73  ? 546 LEU A CD2 1 
ATOM   3718  N N   . GLY A 1 487 ? -80.276  -15.583 64.222  1.00 42.15  ? 547 GLY A N   1 
ATOM   3719  C CA  . GLY A 1 487 ? -81.680  -15.446 63.797  1.00 46.59  ? 547 GLY A CA  1 
ATOM   3720  C C   . GLY A 1 487 ? -81.856  -14.406 62.692  1.00 52.12  ? 547 GLY A C   1 
ATOM   3721  O O   . GLY A 1 487 ? -82.447  -14.755 61.655  1.00 48.80  ? 547 GLY A O   1 
ATOM   3722  N N   . LEU A 1 488 ? -81.389  -13.167 62.902  1.00 49.49  ? 548 LEU A N   1 
ATOM   3723  C CA  . LEU A 1 488 ? -81.469  -12.093 61.883  1.00 56.06  ? 548 LEU A CA  1 
ATOM   3724  C C   . LEU A 1 488 ? -80.818  -12.583 60.568  1.00 64.80  ? 548 LEU A C   1 
ATOM   3725  O O   . LEU A 1 488 ? -81.339  -12.282 59.449  1.00 71.42  ? 548 LEU A O   1 
ATOM   3726  C CB  . LEU A 1 488 ? -80.766  -10.845 62.428  1.00 56.02  ? 548 LEU A CB  1 
ATOM   3727  C CG  . LEU A 1 488 ? -81.481  -10.142 63.571  1.00 54.39  ? 548 LEU A CG  1 
ATOM   3728  C CD1 . LEU A 1 488 ? -80.690  -8.940  64.061  1.00 55.26  ? 548 LEU A CD1 1 
ATOM   3729  C CD2 . LEU A 1 488 ? -82.839  -9.695  63.097  1.00 58.99  ? 548 LEU A CD2 1 
ATOM   3730  N N   . VAL A 1 489 ? -79.711  -13.318 60.670  1.00 62.30  ? 549 VAL A N   1 
ATOM   3731  C CA  . VAL A 1 489 ? -78.981  -13.843 59.483  1.00 60.55  ? 549 VAL A CA  1 
ATOM   3732  C C   . VAL A 1 489 ? -79.821  -14.953 58.838  1.00 52.47  ? 549 VAL A C   1 
ATOM   3733  O O   . VAL A 1 489 ? -80.224  -14.717 57.719  1.00 56.08  ? 549 VAL A O   1 
ATOM   3734  C CB  . VAL A 1 489 ? -77.545  -14.278 59.831  1.00 58.95  ? 549 VAL A CB  1 
ATOM   3735  C CG1 . VAL A 1 489 ? -76.870  -15.060 58.707  1.00 58.24  ? 549 VAL A CG1 1 
ATOM   3736  C CG2 . VAL A 1 489 ? -76.714  -13.067 60.232  1.00 59.42  ? 549 VAL A CG2 1 
ATOM   3737  N N   . ILE A 1 490 ? -80.124  -16.070 59.509  1.00 50.55  ? 550 ILE A N   1 
ATOM   3738  C CA  . ILE A 1 490 ? -80.694  -17.292 58.845  1.00 58.15  ? 550 ILE A CA  1 
ATOM   3739  C C   . ILE A 1 490 ? -82.096  -17.023 58.269  1.00 56.57  ? 550 ILE A C   1 
ATOM   3740  O O   . ILE A 1 490 ? -82.616  -17.900 57.546  1.00 50.47  ? 550 ILE A O   1 
ATOM   3741  C CB  . ILE A 1 490 ? -80.719  -18.509 59.783  1.00 63.23  ? 550 ILE A CB  1 
ATOM   3742  C CG1 . ILE A 1 490 ? -81.660  -18.309 60.977  1.00 64.53  ? 550 ILE A CG1 1 
ATOM   3743  C CG2 . ILE A 1 490 ? -79.305  -18.913 60.186  1.00 62.39  ? 550 ILE A CG2 1 
ATOM   3744  C CD1 . ILE A 1 490 ? -81.633  -19.483 61.972  1.00 70.47  ? 550 ILE A CD1 1 
ATOM   3745  N N   . SER A 1 491 ? -82.698  -15.883 58.612  1.00 55.61  ? 551 SER A N   1 
ATOM   3746  C CA  . SER A 1 491 ? -84.030  -15.419 58.147  1.00 50.34  ? 551 SER A CA  1 
ATOM   3747  C C   . SER A 1 491 ? -83.849  -14.350 57.069  1.00 47.38  ? 551 SER A C   1 
ATOM   3748  O O   . SER A 1 491 ? -84.804  -14.044 56.369  1.00 51.80  ? 551 SER A O   1 
ATOM   3749  C CB  . SER A 1 491 ? -84.845  -14.870 59.310  1.00 52.77  ? 551 SER A CB  1 
ATOM   3750  O OG  . SER A 1 491 ? -84.559  -13.488 59.578  1.00 50.42  ? 551 SER A OG  1 
ATOM   3751  N N   . GLY A 1 492 ? -82.685  -13.739 57.008  1.00 50.35  ? 552 GLY A N   1 
ATOM   3752  C CA  . GLY A 1 492 ? -82.444  -12.601 56.110  1.00 53.43  ? 552 GLY A CA  1 
ATOM   3753  C C   . GLY A 1 492 ? -83.229  -11.368 56.524  1.00 51.58  ? 552 GLY A C   1 
ATOM   3754  O O   . GLY A 1 492 ? -83.649  -10.592 55.647  1.00 53.00  ? 552 GLY A O   1 
ATOM   3755  N N   . ALA A 1 493 ? -83.413  -11.171 57.819  1.00 44.17  ? 553 ALA A N   1 
ATOM   3756  C CA  . ALA A 1 493 ? -84.102  -9.976  58.344  1.00 47.86  ? 553 ALA A CA  1 
ATOM   3757  C C   . ALA A 1 493 ? -83.388  -8.718  57.849  1.00 47.22  ? 553 ALA A C   1 
ATOM   3758  O O   . ALA A 1 493 ? -82.166  -8.755  57.747  1.00 47.32  ? 553 ALA A O   1 
ATOM   3759  C CB  . ALA A 1 493 ? -84.141  -10.039 59.838  1.00 52.98  ? 553 ALA A CB  1 
ATOM   3760  N N   . VAL A 1 494 ? -84.142  -7.668  57.543  1.00 52.14  ? 554 VAL A N   1 
ATOM   3761  C CA  . VAL A 1 494 ? -83.635  -6.404  56.927  1.00 60.05  ? 554 VAL A CA  1 
ATOM   3762  C C   . VAL A 1 494 ? -83.729  -5.260  57.933  1.00 58.65  ? 554 VAL A C   1 
ATOM   3763  O O   . VAL A 1 494 ? -83.295  -4.140  57.604  1.00 56.18  ? 554 VAL A O   1 
ATOM   3764  C CB  . VAL A 1 494 ? -84.435  -6.041  55.659  1.00 68.28  ? 554 VAL A CB  1 
ATOM   3765  C CG1 . VAL A 1 494 ? -84.389  -7.156  54.628  1.00 75.41  ? 554 VAL A CG1 1 
ATOM   3766  C CG2 . VAL A 1 494 ? -85.878  -5.646  55.980  1.00 66.53  ? 554 VAL A CG2 1 
ATOM   3767  N N   . ARG A 1 495 ? -84.387  -5.508  59.062  1.00 62.02  ? 555 ARG A N   1 
ATOM   3768  C CA  . ARG A 1 495 ? -84.585  -4.503  60.138  1.00 69.69  ? 555 ARG A CA  1 
ATOM   3769  C C   . ARG A 1 495 ? -84.721  -5.246  61.471  1.00 66.04  ? 555 ARG A C   1 
ATOM   3770  O O   . ARG A 1 495 ? -85.101  -6.444  61.453  1.00 67.36  ? 555 ARG A O   1 
ATOM   3771  C CB  . ARG A 1 495 ? -85.817  -3.635  59.885  1.00 67.68  ? 555 ARG A CB  1 
ATOM   3772  C CG  . ARG A 1 495 ? -85.734  -2.279  60.561  1.00 80.50  ? 555 ARG A CG  1 
ATOM   3773  C CD  . ARG A 1 495 ? -86.714  -1.267  59.992  1.00 90.67  ? 555 ARG A CD  1 
ATOM   3774  N NE  . ARG A 1 495 ? -88.032  -1.392  60.604  1.00 101.03 ? 555 ARG A NE  1 
ATOM   3775  C CZ  . ARG A 1 495 ? -89.198  -1.097  60.028  1.00 102.17 ? 555 ARG A CZ  1 
ATOM   3776  N NH1 . ARG A 1 495 ? -89.238  -0.640  58.788  1.00 103.25 ? 555 ARG A NH1 1 
ATOM   3777  N NH2 . ARG A 1 495 ? -90.321  -1.274  60.705  1.00 95.05  ? 555 ARG A NH2 1 
ATOM   3778  N N   . VAL A 1 496 ? -84.387  -4.568  62.568  1.00 55.94  ? 556 VAL A N   1 
ATOM   3779  C CA  . VAL A 1 496 ? -84.579  -5.087  63.947  1.00 59.56  ? 556 VAL A CA  1 
ATOM   3780  C C   . VAL A 1 496 ? -85.862  -4.475  64.517  1.00 62.70  ? 556 VAL A C   1 
ATOM   3781  O O   . VAL A 1 496 ? -86.033  -3.219  64.409  1.00 76.73  ? 556 VAL A O   1 
ATOM   3782  C CB  . VAL A 1 496 ? -83.338  -4.773  64.786  1.00 56.94  ? 556 VAL A CB  1 
ATOM   3783  C CG1 . VAL A 1 496 ? -83.526  -5.116  66.249  1.00 58.98  ? 556 VAL A CG1 1 
ATOM   3784  C CG2 . VAL A 1 496 ? -82.136  -5.496  64.201  1.00 58.45  ? 556 VAL A CG2 1 
ATOM   3785  N N   . HIS A 1 497 ? -86.743  -5.323  65.052  1.00 55.91  ? 557 HIS A N   1 
ATOM   3786  C CA  . HIS A 1 497 ? -88.050  -4.907  65.624  1.00 64.15  ? 557 HIS A CA  1 
ATOM   3787  C C   . HIS A 1 497 ? -88.062  -5.219  67.124  1.00 63.26  ? 557 HIS A C   1 
ATOM   3788  O O   . HIS A 1 497 ? -87.723  -6.371  67.493  1.00 56.65  ? 557 HIS A O   1 
ATOM   3789  C CB  . HIS A 1 497 ? -89.253  -5.548  64.902  1.00 65.90  ? 557 HIS A CB  1 
ATOM   3790  C CG  . HIS A 1 497 ? -90.542  -4.801  65.084  1.00 70.15  ? 557 HIS A CG  1 
ATOM   3791  N ND1 . HIS A 1 497 ? -91.272  -4.815  66.263  1.00 82.57  ? 557 HIS A ND1 1 
ATOM   3792  C CD2 . HIS A 1 497 ? -91.236  -4.012  64.241  1.00 73.56  ? 557 HIS A CD2 1 
ATOM   3793  C CE1 . HIS A 1 497 ? -92.353  -4.072  66.131  1.00 81.54  ? 557 HIS A CE1 1 
ATOM   3794  N NE2 . HIS A 1 497 ? -92.352  -3.560  64.907  1.00 81.47  ? 557 HIS A NE2 1 
ATOM   3795  N N   . GLU A 1 498 ? -88.460  -4.233  67.938  1.00 56.73  ? 558 GLU A N   1 
ATOM   3796  C CA  . GLU A 1 498 ? -88.597  -4.412  69.399  1.00 53.94  ? 558 GLU A CA  1 
ATOM   3797  C C   . GLU A 1 498 ? -89.219  -5.784  69.666  1.00 47.85  ? 558 GLU A C   1 
ATOM   3798  O O   . GLU A 1 498 ? -88.781  -6.444  70.600  1.00 45.59  ? 558 GLU A O   1 
ATOM   3799  C CB  . GLU A 1 498 ? -89.342  -3.259  70.055  1.00 58.58  ? 558 GLU A CB  1 
ATOM   3800  C CG  . GLU A 1 498 ? -90.520  -2.711  69.282  1.00 67.87  ? 558 GLU A CG  1 
ATOM   3801  C CD  . GLU A 1 498 ? -90.766  -1.229  69.582  1.00 84.16  ? 558 GLU A CD  1 
ATOM   3802  O OE1 . GLU A 1 498 ? -91.273  -0.894  70.695  1.00 74.75  ? 558 GLU A OE1 1 
ATOM   3803  O OE2 . GLU A 1 498 ? -90.447  -0.390  68.699  1.00 95.96  ? 558 GLU A OE2 1 
ATOM   3804  N N   . ASP A 1 499 ? -90.152  -6.243  68.837  1.00 46.54  ? 559 ASP A N   1 
ATOM   3805  C CA  . ASP A 1 499 ? -90.847  -7.537  69.056  1.00 55.19  ? 559 ASP A CA  1 
ATOM   3806  C C   . ASP A 1 499 ? -89.869  -8.728  69.025  1.00 58.49  ? 559 ASP A C   1 
ATOM   3807  O O   . ASP A 1 499 ? -90.232  -9.793  69.596  1.00 47.41  ? 559 ASP A O   1 
ATOM   3808  C CB  . ASP A 1 499 ? -92.001  -7.726  68.075  1.00 57.36  ? 559 ASP A CB  1 
ATOM   3809  C CG  . ASP A 1 499 ? -93.244  -6.897  68.377  1.00 62.26  ? 559 ASP A CG  1 
ATOM   3810  O OD1 . ASP A 1 499 ? -93.111  -5.738  68.847  1.00 60.07  ? 559 ASP A OD1 1 
ATOM   3811  O OD2 . ASP A 1 499 ? -94.343  -7.407  68.112  1.00 73.24  ? 559 ASP A OD2 1 
ATOM   3812  N N   . MET A 1 500 ? -88.685  -8.584  68.403  1.00 61.93  ? 560 MET A N   1 
ATOM   3813  C CA  . MET A 1 500 ? -87.664  -9.676  68.280  1.00 58.93  ? 560 MET A CA  1 
ATOM   3814  C C   . MET A 1 500 ? -86.856  -9.790  69.588  1.00 62.96  ? 560 MET A C   1 
ATOM   3815  O O   . MET A 1 500 ? -86.506  -10.915 70.022  1.00 74.86  ? 560 MET A O   1 
ATOM   3816  C CB  . MET A 1 500 ? -86.719  -9.412  67.100  1.00 59.80  ? 560 MET A CB  1 
ATOM   3817  C CG  . MET A 1 500 ? -87.445  -9.119  65.802  1.00 57.95  ? 560 MET A CG  1 
ATOM   3818  S SD  . MET A 1 500 ? -86.542  -9.513  64.311  1.00 62.15  ? 560 MET A SD  1 
ATOM   3819  C CE  . MET A 1 500 ? -86.296  -7.894  63.594  1.00 54.35  ? 560 MET A CE  1 
ATOM   3820  N N   . LEU A 1 501 ? -86.553  -8.650  70.197  1.00 61.73  ? 561 LEU A N   1 
ATOM   3821  C CA  . LEU A 1 501 ? -85.942  -8.583  71.543  1.00 55.47  ? 561 LEU A CA  1 
ATOM   3822  C C   . LEU A 1 501 ? -86.829  -9.387  72.497  1.00 54.10  ? 561 LEU A C   1 
ATOM   3823  O O   . LEU A 1 501 ? -86.261  -10.213 73.229  1.00 63.84  ? 561 LEU A O   1 
ATOM   3824  C CB  . LEU A 1 501 ? -85.803  -7.114  71.945  1.00 51.80  ? 561 LEU A CB  1 
ATOM   3825  C CG  . LEU A 1 501 ? -85.034  -6.278  70.920  1.00 53.92  ? 561 LEU A CG  1 
ATOM   3826  C CD1 . LEU A 1 501 ? -85.021  -4.805  71.308  1.00 57.73  ? 561 LEU A CD1 1 
ATOM   3827  C CD2 . LEU A 1 501 ? -83.616  -6.797  70.753  1.00 60.42  ? 561 LEU A CD2 1 
ATOM   3828  N N   . LEU A 1 502 ? -88.157  -9.222  72.432  1.00 49.47  ? 562 LEU A N   1 
ATOM   3829  C CA  . LEU A 1 502 ? -89.118  -9.916  73.354  1.00 49.43  ? 562 LEU A CA  1 
ATOM   3830  C C   . LEU A 1 502 ? -89.103  -11.413 73.042  1.00 53.67  ? 562 LEU A C   1 
ATOM   3831  O O   . LEU A 1 502 ? -89.075  -12.205 73.991  1.00 47.34  ? 562 LEU A O   1 
ATOM   3832  C CB  . LEU A 1 502 ? -90.551  -9.381  73.233  1.00 42.46  ? 562 LEU A CB  1 
ATOM   3833  C CG  . LEU A 1 502 ? -90.749  -7.864  73.285  1.00 41.37  ? 562 LEU A CG  1 
ATOM   3834  C CD1 . LEU A 1 502 ? -92.207  -7.512  73.171  1.00 39.59  ? 562 LEU A CD1 1 
ATOM   3835  C CD2 . LEU A 1 502 ? -90.180  -7.256  74.544  1.00 47.92  ? 562 LEU A CD2 1 
ATOM   3836  N N   . ALA A 1 503 ? -89.110  -11.759 71.749  1.00 57.44  ? 563 ALA A N   1 
ATOM   3837  C CA  . ALA A 1 503 ? -89.147  -13.153 71.245  1.00 53.93  ? 563 ALA A CA  1 
ATOM   3838  C C   . ALA A 1 503 ? -87.938  -13.899 71.814  1.00 56.48  ? 563 ALA A C   1 
ATOM   3839  O O   . ALA A 1 503 ? -88.085  -15.074 72.229  1.00 57.79  ? 563 ALA A O   1 
ATOM   3840  C CB  . ALA A 1 503 ? -89.171  -13.138 69.727  1.00 49.18  ? 563 ALA A CB  1 
ATOM   3841  N N   . ALA A 1 504 ? -86.792  -13.208 71.825  1.00 57.23  ? 564 ALA A N   1 
ATOM   3842  C CA  . ALA A 1 504 ? -85.504  -13.689 72.365  1.00 55.56  ? 564 ALA A CA  1 
ATOM   3843  C C   . ALA A 1 504 ? -85.626  -13.888 73.886  1.00 60.75  ? 564 ALA A C   1 
ATOM   3844  O O   . ALA A 1 504 ? -85.345  -15.008 74.414  1.00 56.42  ? 564 ALA A O   1 
ATOM   3845  C CB  . ALA A 1 504 ? -84.446  -12.690 72.018  1.00 54.91  ? 564 ALA A CB  1 
ATOM   3846  N N   . SER A 1 505 ? -86.049  -12.828 74.572  1.00 48.37  ? 565 SER A N   1 
ATOM   3847  C CA  . SER A 1 505 ? -86.216  -12.827 76.039  1.00 50.40  ? 565 SER A CA  1 
ATOM   3848  C C   . SER A 1 505 ? -87.048  -14.049 76.444  1.00 54.03  ? 565 SER A C   1 
ATOM   3849  O O   . SER A 1 505 ? -86.616  -14.814 77.314  1.00 52.53  ? 565 SER A O   1 
ATOM   3850  C CB  . SER A 1 505 ? -86.835  -11.539 76.488  1.00 52.26  ? 565 SER A CB  1 
ATOM   3851  O OG  . SER A 1 505 ? -86.167  -10.418 75.920  1.00 51.61  ? 565 SER A OG  1 
ATOM   3852  N N   . LYS A 1 506 ? -88.200  -14.232 75.797  1.00 62.56  ? 566 LYS A N   1 
ATOM   3853  C CA  . LYS A 1 506 ? -89.096  -15.408 75.953  1.00 67.15  ? 566 LYS A CA  1 
ATOM   3854  C C   . LYS A 1 506 ? -88.272  -16.691 75.844  1.00 61.77  ? 566 LYS A C   1 
ATOM   3855  O O   . LYS A 1 506 ? -88.351  -17.561 76.730  1.00 52.55  ? 566 LYS A O   1 
ATOM   3856  C CB  . LYS A 1 506 ? -90.073  -15.468 74.772  1.00 92.29  ? 566 LYS A CB  1 
ATOM   3857  C CG  . LYS A 1 506 ? -91.439  -16.069 75.056  1.00 108.84 ? 566 LYS A CG  1 
ATOM   3858  C CD  . LYS A 1 506 ? -92.530  -15.022 75.069  1.00 108.85 ? 566 LYS A CD  1 
ATOM   3859  C CE  . LYS A 1 506 ? -93.911  -15.639 75.147  1.00 114.30 ? 566 LYS A CE  1 
ATOM   3860  N NZ  . LYS A 1 506 ? -94.775  -15.137 74.054  1.00 122.81 ? 566 LYS A NZ  1 
ATOM   3861  N N   . ALA A 1 507 ? -87.515  -16.801 74.750  1.00 62.51  ? 567 ALA A N   1 
ATOM   3862  C CA  . ALA A 1 507 ? -86.846  -18.054 74.338  1.00 61.78  ? 567 ALA A CA  1 
ATOM   3863  C C   . ALA A 1 507 ? -85.827  -18.463 75.411  1.00 60.69  ? 567 ALA A C   1 
ATOM   3864  O O   . ALA A 1 507 ? -85.741  -19.676 75.740  1.00 65.09  ? 567 ALA A O   1 
ATOM   3865  C CB  . ALA A 1 507 ? -86.231  -17.854 72.980  1.00 59.29  ? 567 ALA A CB  1 
ATOM   3866  N N   . LEU A 1 508 ? -85.087  -17.479 75.924  1.00 52.56  ? 568 LEU A N   1 
ATOM   3867  C CA  . LEU A 1 508 ? -84.038  -17.702 76.945  1.00 53.51  ? 568 LEU A CA  1 
ATOM   3868  C C   . LEU A 1 508 ? -84.697  -18.152 78.248  1.00 55.02  ? 568 LEU A C   1 
ATOM   3869  O O   . LEU A 1 508 ? -84.287  -19.167 78.824  1.00 52.73  ? 568 LEU A O   1 
ATOM   3870  C CB  . LEU A 1 508 ? -83.263  -16.398 77.144  1.00 54.08  ? 568 LEU A CB  1 
ATOM   3871  C CG  . LEU A 1 508 ? -82.209  -16.452 78.242  1.00 58.81  ? 568 LEU A CG  1 
ATOM   3872  C CD1 . LEU A 1 508 ? -81.206  -17.563 77.936  1.00 57.04  ? 568 LEU A CD1 1 
ATOM   3873  C CD2 . LEU A 1 508 ? -81.543  -15.086 78.418  1.00 64.40  ? 568 LEU A CD2 1 
ATOM   3874  N N   . ALA A 1 509 ? -85.683  -17.377 78.683  1.00 62.59  ? 569 ALA A N   1 
ATOM   3875  C CA  . ALA A 1 509 ? -86.449  -17.576 79.929  1.00 55.32  ? 569 ALA A CA  1 
ATOM   3876  C C   . ALA A 1 509 ? -87.039  -18.988 79.902  1.00 46.16  ? 569 ALA A C   1 
ATOM   3877  O O   . ALA A 1 509 ? -87.052  -19.619 80.942  1.00 39.91  ? 569 ALA A O   1 
ATOM   3878  C CB  . ALA A 1 509 ? -87.507  -16.501 80.052  1.00 52.26  ? 569 ALA A CB  1 
ATOM   3879  N N   . ASP A 1 510 ? -87.460  -19.474 78.736  1.00 53.92  ? 570 ASP A N   1 
ATOM   3880  C CA  . ASP A 1 510 ? -88.172  -20.775 78.586  1.00 66.93  ? 570 ASP A CA  1 
ATOM   3881  C C   . ASP A 1 510 ? -87.152  -21.914 78.546  1.00 62.50  ? 570 ASP A C   1 
ATOM   3882  O O   . ASP A 1 510 ? -87.588  -23.070 78.546  1.00 71.72  ? 570 ASP A O   1 
ATOM   3883  C CB  . ASP A 1 510 ? -89.118  -20.793 77.373  1.00 81.93  ? 570 ASP A CB  1 
ATOM   3884  C CG  . ASP A 1 510 ? -90.057  -22.002 77.333  1.00 108.53 ? 570 ASP A CG  1 
ATOM   3885  O OD1 . ASP A 1 510 ? -90.542  -22.415 78.415  1.00 121.04 ? 570 ASP A OD1 1 
ATOM   3886  O OD2 . ASP A 1 510 ? -90.313  -22.532 76.218  1.00 143.11 ? 570 ASP A OD2 1 
ATOM   3887  N N   . GLN A 1 511 ? -85.857  -21.599 78.562  1.00 67.52  ? 571 GLN A N   1 
ATOM   3888  C CA  . GLN A 1 511 ? -84.762  -22.592 78.705  1.00 62.74  ? 571 GLN A CA  1 
ATOM   3889  C C   . GLN A 1 511 ? -84.367  -22.748 80.183  1.00 63.64  ? 571 GLN A C   1 
ATOM   3890  O O   . GLN A 1 511 ? -83.713  -23.775 80.491  1.00 68.83  ? 571 GLN A O   1 
ATOM   3891  C CB  . GLN A 1 511 ? -83.564  -22.157 77.877  1.00 62.31  ? 571 GLN A CB  1 
ATOM   3892  C CG  . GLN A 1 511 ? -83.815  -22.279 76.399  1.00 67.33  ? 571 GLN A CG  1 
ATOM   3893  C CD  . GLN A 1 511 ? -84.114  -23.706 76.003  1.00 76.44  ? 571 GLN A CD  1 
ATOM   3894  O OE1 . GLN A 1 511 ? -83.514  -24.668 76.510  1.00 70.87  ? 571 GLN A OE1 1 
ATOM   3895  N NE2 . GLN A 1 511 ? -85.020  -23.842 75.041  1.00 82.75  ? 571 GLN A NE2 1 
ATOM   3896  N N   . ALA A 1 512 ? -84.770  -21.796 81.047  1.00 63.51  ? 572 ALA A N   1 
ATOM   3897  C CA  . ALA A 1 512 ? -84.539  -21.792 82.509  1.00 56.22  ? 572 ALA A CA  1 
ATOM   3898  C C   . ALA A 1 512 ? -85.452  -22.823 83.162  1.00 53.24  ? 572 ALA A C   1 
ATOM   3899  O O   . ALA A 1 512 ? -86.644  -22.571 83.242  1.00 61.78  ? 572 ALA A O   1 
ATOM   3900  C CB  . ALA A 1 512 ? -84.771  -20.417 83.098  1.00 52.49  ? 572 ALA A CB  1 
ATOM   3901  N N   . THR A 1 513 ? -84.901  -23.956 83.572  1.00 57.75  ? 573 THR A N   1 
ATOM   3902  C CA  . THR A 1 513 ? -85.657  -25.066 84.205  1.00 71.93  ? 573 THR A CA  1 
ATOM   3903  C C   . THR A 1 513 ? -85.343  -25.070 85.701  1.00 74.68  ? 573 THR A C   1 
ATOM   3904  O O   . THR A 1 513 ? -84.642  -24.162 86.160  1.00 73.60  ? 573 THR A O   1 
ATOM   3905  C CB  . THR A 1 513 ? -85.334  -26.413 83.553  1.00 67.32  ? 573 THR A CB  1 
ATOM   3906  O OG1 . THR A 1 513 ? -84.137  -26.867 84.195  1.00 67.21  ? 573 THR A OG1 1 
ATOM   3907  C CG2 . THR A 1 513 ? -85.181  -26.301 82.056  1.00 65.59  ? 573 THR A CG2 1 
ATOM   3908  N N   . GLN A 1 514 ? -85.853  -26.072 86.411  1.00 80.49  ? 574 GLN A N   1 
ATOM   3909  C CA  . GLN A 1 514 ? -85.615  -26.329 87.845  1.00 89.09  ? 574 GLN A CA  1 
ATOM   3910  C C   . GLN A 1 514 ? -84.157  -26.712 88.084  1.00 98.76  ? 574 GLN A C   1 
ATOM   3911  O O   . GLN A 1 514 ? -83.665  -26.437 89.204  1.00 102.72 ? 574 GLN A O   1 
ATOM   3912  C CB  . GLN A 1 514 ? -86.453  -27.524 88.321  1.00 98.51  ? 574 GLN A CB  1 
ATOM   3913  C CG  . GLN A 1 514 ? -87.845  -27.155 88.788  1.00 97.33  ? 574 GLN A CG  1 
ATOM   3914  C CD  . GLN A 1 514 ? -87.873  -25.798 89.444  1.00 97.15  ? 574 GLN A CD  1 
ATOM   3915  O OE1 . GLN A 1 514 ? -88.349  -24.835 88.859  1.00 107.71 ? 574 GLN A OE1 1 
ATOM   3916  N NE2 . GLN A 1 514 ? -87.333  -25.707 90.648  1.00 84.56  ? 574 GLN A NE2 1 
ATOM   3917  N N   . ASP A 1 515 ? -83.511  -27.358 87.105  1.00 100.41 ? 575 ASP A N   1 
ATOM   3918  C CA  . ASP A 1 515 ? -82.114  -27.851 87.237  1.00 104.06 ? 575 ASP A CA  1 
ATOM   3919  C C   . ASP A 1 515 ? -81.250  -26.664 87.694  1.00 93.97  ? 575 ASP A C   1 
ATOM   3920  O O   . ASP A 1 515 ? -80.449  -26.819 88.641  1.00 76.41  ? 575 ASP A O   1 
ATOM   3921  C CB  . ASP A 1 515 ? -81.620  -28.504 85.945  1.00 106.84 ? 575 ASP A CB  1 
ATOM   3922  C CG  . ASP A 1 515 ? -82.552  -29.583 85.407  1.00 109.76 ? 575 ASP A CG  1 
ATOM   3923  O OD1 . ASP A 1 515 ? -83.721  -29.674 85.897  1.00 93.72  ? 575 ASP A OD1 1 
ATOM   3924  O OD2 . ASP A 1 515 ? -82.127  -30.293 84.476  1.00 105.58 ? 575 ASP A OD2 1 
ATOM   3925  N N   . ASN A 1 516 ? -81.455  -25.502 87.077  1.00 83.66  ? 576 ASN A N   1 
ATOM   3926  C CA  . ASN A 1 516 ? -80.659  -24.284 87.369  1.00 80.78  ? 576 ASN A CA  1 
ATOM   3927  C C   . ASN A 1 516 ? -81.350  -23.473 88.470  1.00 65.16  ? 576 ASN A C   1 
ATOM   3928  O O   . ASN A 1 516 ? -80.634  -22.854 89.251  1.00 63.12  ? 576 ASN A O   1 
ATOM   3929  C CB  . ASN A 1 516 ? -80.336  -23.484 86.110  1.00 83.95  ? 576 ASN A CB  1 
ATOM   3930  C CG  . ASN A 1 516 ? -81.547  -23.151 85.275  1.00 89.24  ? 576 ASN A CG  1 
ATOM   3931  O OD1 . ASN A 1 516 ? -82.014  -23.995 84.506  1.00 86.04  ? 576 ASN A OD1 1 
ATOM   3932  N ND2 . ASN A 1 516 ? -82.007  -21.914 85.399  1.00 85.35  ? 576 ASN A ND2 1 
ATOM   3933  N N   . PHE A 1 517 ? -82.676  -23.504 88.568  1.00 61.34  ? 577 PHE A N   1 
ATOM   3934  C CA  . PHE A 1 517 ? -83.431  -22.817 89.659  1.00 61.07  ? 577 PHE A CA  1 
ATOM   3935  C C   . PHE A 1 517 ? -83.107  -23.433 91.025  1.00 66.59  ? 577 PHE A C   1 
ATOM   3936  O O   . PHE A 1 517 ? -82.947  -22.635 91.967  1.00 59.19  ? 577 PHE A O   1 
ATOM   3937  C CB  . PHE A 1 517 ? -84.947  -22.880 89.447  1.00 57.15  ? 577 PHE A CB  1 
ATOM   3938  C CG  . PHE A 1 517 ? -85.483  -22.035 88.317  1.00 52.86  ? 577 PHE A CG  1 
ATOM   3939  C CD1 . PHE A 1 517 ? -84.786  -20.955 87.810  1.00 52.84  ? 577 PHE A CD1 1 
ATOM   3940  C CD2 . PHE A 1 517 ? -86.711  -22.332 87.766  1.00 53.43  ? 577 PHE A CD2 1 
ATOM   3941  C CE1 . PHE A 1 517 ? -85.294  -20.218 86.751  1.00 59.68  ? 577 PHE A CE1 1 
ATOM   3942  C CE2 . PHE A 1 517 ? -87.222  -21.591 86.717  1.00 52.87  ? 577 PHE A CE2 1 
ATOM   3943  C CZ  . PHE A 1 517 ? -86.512  -20.539 86.206  1.00 56.99  ? 577 PHE A CZ  1 
ATOM   3944  N N   . GLU A 1 518 ? -83.051  -24.778 91.129  1.00 73.27  ? 578 GLU A N   1 
ATOM   3945  C CA  . GLU A 1 518 ? -82.575  -25.528 92.325  1.00 72.62  ? 578 GLU A CA  1 
ATOM   3946  C C   . GLU A 1 518 ? -81.390  -24.773 92.944  1.00 66.21  ? 578 GLU A C   1 
ATOM   3947  O O   . GLU A 1 518 ? -81.485  -24.428 94.096  1.00 76.04  ? 578 GLU A O   1 
ATOM   3948  C CB  . GLU A 1 518 ? -82.117  -26.944 91.952  1.00 90.36  ? 578 GLU A CB  1 
ATOM   3949  C CG  . GLU A 1 518 ? -83.174  -28.039 92.019  1.00 98.05  ? 578 GLU A CG  1 
ATOM   3950  C CD  . GLU A 1 518 ? -82.743  -29.337 91.319  1.00 110.50 ? 578 GLU A CD  1 
ATOM   3951  O OE1 . GLU A 1 518 ? -81.522  -29.623 91.317  1.00 101.25 ? 578 GLU A OE1 1 
ATOM   3952  O OE2 . GLU A 1 518 ? -83.612  -30.043 90.718  1.00 114.95 ? 578 GLU A OE2 1 
ATOM   3953  N N   . LYS A 1 519 ? -80.335  -24.493 92.169  1.00 67.86  ? 579 LYS A N   1 
ATOM   3954  C CA  . LYS A 1 519 ? -79.050  -23.896 92.622  1.00 67.00  ? 579 LYS A CA  1 
ATOM   3955  C C   . LYS A 1 519 ? -79.164  -22.368 92.749  1.00 57.30  ? 579 LYS A C   1 
ATOM   3956  O O   . LYS A 1 519 ? -78.139  -21.759 93.035  1.00 64.83  ? 579 LYS A O   1 
ATOM   3957  C CB  . LYS A 1 519 ? -77.912  -24.201 91.638  1.00 87.12  ? 579 LYS A CB  1 
ATOM   3958  C CG  . LYS A 1 519 ? -77.804  -25.648 91.163  1.00 100.87 ? 579 LYS A CG  1 
ATOM   3959  C CD  . LYS A 1 519 ? -76.965  -25.837 89.914  1.00 106.65 ? 579 LYS A CD  1 
ATOM   3960  C CE  . LYS A 1 519 ? -77.222  -27.170 89.228  1.00 96.64  ? 579 LYS A CE  1 
ATOM   3961  N NZ  . LYS A 1 519 ? -76.235  -27.464 88.158  1.00 96.80  ? 579 LYS A NZ  1 
ATOM   3962  N N   . GLY A 1 520 ? -80.323  -21.752 92.498  1.00 48.92  ? 580 GLY A N   1 
ATOM   3963  C CA  . GLY A 1 520 ? -80.547  -20.303 92.666  1.00 45.73  ? 580 GLY A CA  1 
ATOM   3964  C C   . GLY A 1 520 ? -80.125  -19.476 91.455  1.00 51.59  ? 580 GLY A C   1 
ATOM   3965  O O   . GLY A 1 520 ? -79.950  -18.252 91.617  1.00 55.77  ? 580 GLY A O   1 
ATOM   3966  N N   . SER A 1 521 ? -80.010  -20.101 90.272  1.00 57.20  ? 581 SER A N   1 
ATOM   3967  C CA  . SER A 1 521 ? -79.569  -19.482 88.987  1.00 56.36  ? 581 SER A CA  1 
ATOM   3968  C C   . SER A 1 521 ? -80.752  -19.260 88.058  1.00 56.86  ? 581 SER A C   1 
ATOM   3969  O O   . SER A 1 521 ? -81.402  -20.262 87.684  1.00 61.46  ? 581 SER A O   1 
ATOM   3970  C CB  . SER A 1 521 ? -78.554  -20.310 88.250  1.00 61.83  ? 581 SER A CB  1 
ATOM   3971  O OG  . SER A 1 521 ? -77.319  -20.342 88.943  1.00 82.33  ? 581 SER A OG  1 
ATOM   3972  N N   . ILE A 1 522 ? -80.961  -18.009 87.640  1.00 60.98  ? 582 ILE A N   1 
ATOM   3973  C CA  . ILE A 1 522 ? -82.059  -17.622 86.717  1.00 56.76  ? 582 ILE A CA  1 
ATOM   3974  C C   . ILE A 1 522 ? -81.798  -18.182 85.310  1.00 65.05  ? 582 ILE A C   1 
ATOM   3975  O O   . ILE A 1 522 ? -82.769  -18.285 84.541  1.00 75.50  ? 582 ILE A O   1 
ATOM   3976  C CB  . ILE A 1 522 ? -82.235  -16.100 86.705  1.00 54.55  ? 582 ILE A CB  1 
ATOM   3977  C CG1 . ILE A 1 522 ? -81.051  -15.352 86.089  1.00 56.85  ? 582 ILE A CG1 1 
ATOM   3978  C CG2 . ILE A 1 522 ? -82.533  -15.608 88.094  1.00 52.63  ? 582 ILE A CG2 1 
ATOM   3979  C CD1 . ILE A 1 522 ? -81.245  -13.844 86.170  1.00 62.94  ? 582 ILE A CD1 1 
ATOM   3980  N N   . PHE A 1 523 ? -80.557  -18.523 84.960  1.00 65.73  ? 583 PHE A N   1 
ATOM   3981  C CA  . PHE A 1 523 ? -80.209  -19.006 83.600  1.00 59.92  ? 583 PHE A CA  1 
ATOM   3982  C C   . PHE A 1 523 ? -79.570  -20.371 83.662  1.00 57.48  ? 583 PHE A C   1 
ATOM   3983  O O   . PHE A 1 523 ? -78.944  -20.722 84.647  1.00 65.25  ? 583 PHE A O   1 
ATOM   3984  C CB  . PHE A 1 523 ? -79.210  -18.080 82.925  1.00 56.82  ? 583 PHE A CB  1 
ATOM   3985  C CG  . PHE A 1 523 ? -79.755  -16.700 82.738  1.00 57.56  ? 583 PHE A CG  1 
ATOM   3986  C CD1 . PHE A 1 523 ? -80.921  -16.492 82.036  1.00 52.40  ? 583 PHE A CD1 1 
ATOM   3987  C CD2 . PHE A 1 523 ? -79.090  -15.615 83.260  1.00 65.79  ? 583 PHE A CD2 1 
ATOM   3988  C CE1 . PHE A 1 523 ? -81.410  -15.214 81.851  1.00 52.05  ? 583 PHE A CE1 1 
ATOM   3989  C CE2 . PHE A 1 523 ? -79.577  -14.336 83.070  1.00 69.55  ? 583 PHE A CE2 1 
ATOM   3990  C CZ  . PHE A 1 523 ? -80.732  -14.143 82.355  1.00 59.01  ? 583 PHE A CZ  1 
ATOM   3991  N N   . PRO A 1 524 ? -79.670  -21.162 82.582  1.00 60.35  ? 584 PRO A N   1 
ATOM   3992  C CA  . PRO A 1 524 ? -78.997  -22.451 82.541  1.00 59.31  ? 584 PRO A CA  1 
ATOM   3993  C C   . PRO A 1 524 ? -77.510  -22.214 82.335  1.00 53.85  ? 584 PRO A C   1 
ATOM   3994  O O   . PRO A 1 524 ? -77.086  -21.137 81.935  1.00 50.89  ? 584 PRO A O   1 
ATOM   3995  C CB  . PRO A 1 524 ? -79.662  -23.193 81.379  1.00 63.05  ? 584 PRO A CB  1 
ATOM   3996  C CG  . PRO A 1 524 ? -80.245  -22.093 80.496  1.00 65.00  ? 584 PRO A CG  1 
ATOM   3997  C CD  . PRO A 1 524 ? -80.414  -20.858 81.354  1.00 61.21  ? 584 PRO A CD  1 
ATOM   3998  N N   . PRO A 1 525 ? -76.673  -23.233 82.604  1.00 61.73  ? 585 PRO A N   1 
ATOM   3999  C CA  . PRO A 1 525 ? -75.227  -23.053 82.519  1.00 65.69  ? 585 PRO A CA  1 
ATOM   4000  C C   . PRO A 1 525 ? -74.821  -22.782 81.053  1.00 63.01  ? 585 PRO A C   1 
ATOM   4001  O O   . PRO A 1 525 ? -75.572  -23.099 80.183  1.00 52.67  ? 585 PRO A O   1 
ATOM   4002  C CB  . PRO A 1 525 ? -74.673  -24.369 83.103  1.00 65.03  ? 585 PRO A CB  1 
ATOM   4003  C CG  . PRO A 1 525 ? -75.852  -25.086 83.736  1.00 61.76  ? 585 PRO A CG  1 
ATOM   4004  C CD  . PRO A 1 525 ? -77.054  -24.614 82.951  1.00 61.39  ? 585 PRO A CD  1 
ATOM   4005  N N   . PHE A 1 526 ? -73.631  -22.228 80.812  1.00 61.87  ? 586 PHE A N   1 
ATOM   4006  C CA  . PHE A 1 526 ? -73.103  -21.930 79.455  1.00 54.21  ? 586 PHE A CA  1 
ATOM   4007  C C   . PHE A 1 526 ? -72.800  -23.209 78.690  1.00 56.27  ? 586 PHE A C   1 
ATOM   4008  O O   . PHE A 1 526 ? -72.738  -23.154 77.448  1.00 69.05  ? 586 PHE A O   1 
ATOM   4009  C CB  . PHE A 1 526 ? -71.850  -21.071 79.513  1.00 46.70  ? 586 PHE A CB  1 
ATOM   4010  C CG  . PHE A 1 526 ? -72.155  -19.604 79.477  1.00 45.08  ? 586 PHE A CG  1 
ATOM   4011  C CD1 . PHE A 1 526 ? -72.798  -19.042 78.399  1.00 42.79  ? 586 PHE A CD1 1 
ATOM   4012  C CD2 . PHE A 1 526 ? -71.768  -18.776 80.518  1.00 53.92  ? 586 PHE A CD2 1 
ATOM   4013  C CE1 . PHE A 1 526 ? -73.024  -17.674 78.350  1.00 51.45  ? 586 PHE A CE1 1 
ATOM   4014  C CE2 . PHE A 1 526 ? -72.001  -17.406 80.477  1.00 50.63  ? 586 PHE A CE2 1 
ATOM   4015  C CZ  . PHE A 1 526 ? -72.629  -16.854 79.389  1.00 51.10  ? 586 PHE A CZ  1 
ATOM   4016  N N   . THR A 1 527 ? -72.649  -24.325 79.395  1.00 53.99  ? 587 THR A N   1 
ATOM   4017  C CA  . THR A 1 527 ? -72.546  -25.678 78.778  1.00 59.43  ? 587 THR A CA  1 
ATOM   4018  C C   . THR A 1 527 ? -73.795  -26.056 77.951  1.00 65.97  ? 587 THR A C   1 
ATOM   4019  O O   . THR A 1 527 ? -73.802  -27.186 77.435  1.00 76.18  ? 587 THR A O   1 
ATOM   4020  C CB  . THR A 1 527 ? -72.324  -26.734 79.853  1.00 58.21  ? 587 THR A CB  1 
ATOM   4021  O OG1 . THR A 1 527 ? -73.441  -26.582 80.735  1.00 63.75  ? 587 THR A OG1 1 
ATOM   4022  C CG2 . THR A 1 527 ? -70.981  -26.579 80.528  1.00 57.97  ? 587 THR A CG2 1 
ATOM   4023  N N   . SER A 1 528 ? -74.810  -25.195 77.823  1.00 62.51  ? 588 SER A N   1 
ATOM   4024  C CA  . SER A 1 528 ? -76.037  -25.440 77.003  1.00 62.16  ? 588 SER A CA  1 
ATOM   4025  C C   . SER A 1 528 ? -76.215  -24.371 75.911  1.00 63.34  ? 588 SER A C   1 
ATOM   4026  O O   . SER A 1 528 ? -77.274  -24.400 75.236  1.00 64.38  ? 588 SER A O   1 
ATOM   4027  C CB  . SER A 1 528 ? -77.288  -25.480 77.884  1.00 65.00  ? 588 SER A CB  1 
ATOM   4028  O OG  . SER A 1 528 ? -77.084  -26.253 79.052  1.00 66.30  ? 588 SER A OG  1 
ATOM   4029  N N   . ILE A 1 529 ? -75.270  -23.428 75.788  1.00 63.00  ? 589 ILE A N   1 
ATOM   4030  C CA  . ILE A 1 529 ? -75.443  -22.156 75.018  1.00 57.27  ? 589 ILE A CA  1 
ATOM   4031  C C   . ILE A 1 529 ? -75.673  -22.482 73.527  1.00 65.56  ? 589 ILE A C   1 
ATOM   4032  O O   . ILE A 1 529 ? -76.230  -21.618 72.787  1.00 61.09  ? 589 ILE A O   1 
ATOM   4033  C CB  . ILE A 1 529 ? -74.238  -21.227 75.244  1.00 56.19  ? 589 ILE A CB  1 
ATOM   4034  C CG1 . ILE A 1 529 ? -74.471  -19.805 74.709  1.00 57.93  ? 589 ILE A CG1 1 
ATOM   4035  C CG2 . ILE A 1 529 ? -72.979  -21.840 74.644  1.00 56.85  ? 589 ILE A CG2 1 
ATOM   4036  C CD1 . ILE A 1 529 ? -75.585  -19.019 75.374  1.00 57.60  ? 589 ILE A CD1 1 
ATOM   4037  N N   . ARG A 1 530 ? -75.281  -23.672 73.067  1.00 64.29  ? 590 ARG A N   1 
ATOM   4038  C CA  . ARG A 1 530 ? -75.596  -24.087 71.676  1.00 66.20  ? 590 ARG A CA  1 
ATOM   4039  C C   . ARG A 1 530 ? -77.109  -24.335 71.560  1.00 62.47  ? 590 ARG A C   1 
ATOM   4040  O O   . ARG A 1 530 ? -77.738  -23.748 70.653  1.00 57.20  ? 590 ARG A O   1 
ATOM   4041  C CB  . ARG A 1 530 ? -74.729  -25.275 71.258  1.00 73.89  ? 590 ARG A CB  1 
ATOM   4042  C CG  . ARG A 1 530 ? -73.251  -24.949 71.046  1.00 79.85  ? 590 ARG A CG  1 
ATOM   4043  C CD  . ARG A 1 530 ? -72.858  -23.609 70.409  1.00 78.54  ? 590 ARG A CD  1 
ATOM   4044  N NE  . ARG A 1 530 ? -72.826  -23.583 68.949  1.00 74.99  ? 590 ARG A NE  1 
ATOM   4045  C CZ  . ARG A 1 530 ? -71.748  -23.806 68.204  1.00 65.75  ? 590 ARG A CZ  1 
ATOM   4046  N NH1 . ARG A 1 530 ? -70.612  -24.132 68.756  1.00 67.58  ? 590 ARG A NH1 1 
ATOM   4047  N NH2 . ARG A 1 530 ? -71.813  -23.787 66.893  1.00 70.51  ? 590 ARG A NH2 1 
ATOM   4048  N N   . LYS A 1 531 ? -77.691  -25.117 72.471  1.00 58.23  ? 591 LYS A N   1 
ATOM   4049  C CA  . LYS A 1 531 ? -79.166  -25.300 72.527  1.00 59.20  ? 591 LYS A CA  1 
ATOM   4050  C C   . LYS A 1 531 ? -79.847  -23.920 72.677  1.00 50.75  ? 591 LYS A C   1 
ATOM   4051  O O   . LYS A 1 531 ? -80.743  -23.632 71.887  1.00 49.96  ? 591 LYS A O   1 
ATOM   4052  C CB  . LYS A 1 531 ? -79.565  -26.294 73.623  1.00 66.25  ? 591 LYS A CB  1 
ATOM   4053  C CG  . LYS A 1 531 ? -80.980  -26.855 73.488  1.00 77.25  ? 591 LYS A CG  1 
ATOM   4054  C CD  . LYS A 1 531 ? -81.542  -27.509 74.747  1.00 94.15  ? 591 LYS A CD  1 
ATOM   4055  C CE  . LYS A 1 531 ? -82.674  -28.480 74.454  1.00 97.37  ? 591 LYS A CE  1 
ATOM   4056  N NZ  . LYS A 1 531 ? -82.375  -29.835 74.978  1.00 91.90  ? 591 LYS A NZ  1 
ATOM   4057  N N   . ILE A 1 532 ? -79.434  -23.071 73.621  1.00 44.72  ? 592 ILE A N   1 
ATOM   4058  C CA  . ILE A 1 532 ? -80.086  -21.749 73.884  1.00 45.41  ? 592 ILE A CA  1 
ATOM   4059  C C   . ILE A 1 532 ? -80.109  -20.872 72.634  1.00 48.43  ? 592 ILE A C   1 
ATOM   4060  O O   . ILE A 1 532 ? -81.154  -20.222 72.402  1.00 45.38  ? 592 ILE A O   1 
ATOM   4061  C CB  . ILE A 1 532 ? -79.376  -20.975 75.005  1.00 50.40  ? 592 ILE A CB  1 
ATOM   4062  C CG1 . ILE A 1 532 ? -79.619  -21.657 76.361  1.00 51.66  ? 592 ILE A CG1 1 
ATOM   4063  C CG2 . ILE A 1 532 ? -79.799  -19.497 74.995  1.00 45.61  ? 592 ILE A CG2 1 
ATOM   4064  C CD1 . ILE A 1 532 ? -78.498  -21.531 77.360  1.00 47.82  ? 592 ILE A CD1 1 
ATOM   4065  N N   . SER A 1 533 ? -78.979  -20.802 71.914  1.00 52.24  ? 593 SER A N   1 
ATOM   4066  C CA  . SER A 1 533 ? -78.809  -19.904 70.745  1.00 52.51  ? 593 SER A CA  1 
ATOM   4067  C C   . SER A 1 533 ? -79.766  -20.337 69.621  1.00 50.57  ? 593 SER A C   1 
ATOM   4068  O O   . SER A 1 533 ? -80.397  -19.437 69.002  1.00 40.85  ? 593 SER A O   1 
ATOM   4069  C CB  . SER A 1 533 ? -77.358  -19.811 70.317  1.00 55.39  ? 593 SER A CB  1 
ATOM   4070  O OG  . SER A 1 533 ? -76.680  -18.836 71.101  1.00 68.94  ? 593 SER A OG  1 
ATOM   4071  N N   . ALA A 1 534 ? -79.899  -21.660 69.395  1.00 52.98  ? 594 ALA A N   1 
ATOM   4072  C CA  . ALA A 1 534 ? -80.787  -22.264 68.365  1.00 51.19  ? 594 ALA A CA  1 
ATOM   4073  C C   . ALA A 1 534 ? -82.234  -21.878 68.658  1.00 49.77  ? 594 ALA A C   1 
ATOM   4074  O O   . ALA A 1 534 ? -82.910  -21.407 67.731  1.00 61.87  ? 594 ALA A O   1 
ATOM   4075  C CB  . ALA A 1 534 ? -80.635  -23.766 68.294  1.00 54.09  ? 594 ALA A CB  1 
ATOM   4076  N N   . HIS A 1 535 ? -82.688  -22.068 69.900  1.00 46.67  ? 595 HIS A N   1 
ATOM   4077  C CA  . HIS A 1 535 ? -84.057  -21.700 70.324  1.00 49.16  ? 595 HIS A CA  1 
ATOM   4078  C C   . HIS A 1 535 ? -84.253  -20.186 70.231  1.00 43.61  ? 595 HIS A C   1 
ATOM   4079  O O   . HIS A 1 535 ? -85.324  -19.790 69.776  1.00 47.15  ? 595 HIS A O   1 
ATOM   4080  C CB  . HIS A 1 535 ? -84.370  -22.271 71.696  1.00 55.54  ? 595 HIS A CB  1 
ATOM   4081  C CG  . HIS A 1 535 ? -84.712  -23.721 71.646  1.00 59.06  ? 595 HIS A CG  1 
ATOM   4082  N ND1 . HIS A 1 535 ? -83.764  -24.713 71.534  1.00 64.66  ? 595 HIS A ND1 1 
ATOM   4083  C CD2 . HIS A 1 535 ? -85.902  -24.348 71.716  1.00 59.56  ? 595 HIS A CD2 1 
ATOM   4084  C CE1 . HIS A 1 535 ? -84.348  -25.893 71.586  1.00 64.99  ? 595 HIS A CE1 1 
ATOM   4085  N NE2 . HIS A 1 535 ? -85.652  -25.694 71.684  1.00 65.78  ? 595 HIS A NE2 1 
ATOM   4086  N N   . ILE A 1 536 ? -83.273  -19.365 70.598  1.00 40.77  ? 596 ILE A N   1 
ATOM   4087  C CA  . ILE A 1 536 ? -83.433  -17.886 70.464  1.00 43.98  ? 596 ILE A CA  1 
ATOM   4088  C C   . ILE A 1 536 ? -83.474  -17.562 68.967  1.00 52.03  ? 596 ILE A C   1 
ATOM   4089  O O   . ILE A 1 536 ? -84.280  -16.718 68.549  1.00 53.73  ? 596 ILE A O   1 
ATOM   4090  C CB  . ILE A 1 536 ? -82.314  -17.127 71.184  1.00 46.81  ? 596 ILE A CB  1 
ATOM   4091  C CG1 . ILE A 1 536 ? -82.349  -17.346 72.695  1.00 44.10  ? 596 ILE A CG1 1 
ATOM   4092  C CG2 . ILE A 1 536 ? -82.325  -15.648 70.815  1.00 50.11  ? 596 ILE A CG2 1 
ATOM   4093  C CD1 . ILE A 1 536 ? -81.150  -16.769 73.432  1.00 48.48  ? 596 ILE A CD1 1 
ATOM   4094  N N   . ALA A 1 537 ? -82.612  -18.189 68.172  1.00 58.78  ? 597 ALA A N   1 
ATOM   4095  C CA  . ALA A 1 537 ? -82.551  -17.926 66.721  1.00 69.55  ? 597 ALA A CA  1 
ATOM   4096  C C   . ALA A 1 537 ? -83.930  -18.226 66.092  1.00 74.97  ? 597 ALA A C   1 
ATOM   4097  O O   . ALA A 1 537 ? -84.496  -17.328 65.411  1.00 79.20  ? 597 ALA A O   1 
ATOM   4098  C CB  . ALA A 1 537 ? -81.436  -18.738 66.114  1.00 71.39  ? 597 ALA A CB  1 
ATOM   4099  N N   . ALA A 1 538 ? -84.464  -19.430 66.338  1.00 77.83  ? 598 ALA A N   1 
ATOM   4100  C CA  . ALA A 1 538 ? -85.745  -19.936 65.789  1.00 70.20  ? 598 ALA A CA  1 
ATOM   4101  C C   . ALA A 1 538 ? -86.841  -18.916 66.118  1.00 69.02  ? 598 ALA A C   1 
ATOM   4102  O O   . ALA A 1 538 ? -87.619  -18.584 65.204  1.00 82.07  ? 598 ALA A O   1 
ATOM   4103  C CB  . ALA A 1 538 ? -86.070  -21.333 66.320  1.00 57.71  ? 598 ALA A CB  1 
ATOM   4104  N N   . ALA A 1 539 ? -86.880  -18.424 67.360  1.00 57.68  ? 599 ALA A N   1 
ATOM   4105  C CA  . ALA A 1 539 ? -87.867  -17.431 67.835  1.00 60.01  ? 599 ALA A CA  1 
ATOM   4106  C C   . ALA A 1 539 ? -87.685  -16.090 67.098  1.00 62.68  ? 599 ALA A C   1 
ATOM   4107  O O   . ALA A 1 539 ? -88.698  -15.539 66.648  1.00 62.87  ? 599 ALA A O   1 
ATOM   4108  C CB  . ALA A 1 539 ? -87.756  -17.254 69.330  1.00 60.17  ? 599 ALA A CB  1 
ATOM   4109  N N   . VAL A 1 540 ? -86.460  -15.562 67.010  1.00 61.95  ? 600 VAL A N   1 
ATOM   4110  C CA  . VAL A 1 540 ? -86.191  -14.210 66.426  1.00 68.52  ? 600 VAL A CA  1 
ATOM   4111  C C   . VAL A 1 540 ? -86.468  -14.241 64.915  1.00 64.76  ? 600 VAL A C   1 
ATOM   4112  O O   . VAL A 1 540 ? -86.811  -13.169 64.336  1.00 48.74  ? 600 VAL A O   1 
ATOM   4113  C CB  . VAL A 1 540 ? -84.755  -13.725 66.705  1.00 65.55  ? 600 VAL A CB  1 
ATOM   4114  C CG1 . VAL A 1 540 ? -84.436  -12.477 65.882  1.00 62.53  ? 600 VAL A CG1 1 
ATOM   4115  C CG2 . VAL A 1 540 ? -84.526  -13.479 68.193  1.00 60.62  ? 600 VAL A CG2 1 
ATOM   4116  N N   . ALA A 1 541 ? -86.274  -15.412 64.305  1.00 60.59  ? 601 ALA A N   1 
ATOM   4117  C CA  . ALA A 1 541 ? -86.547  -15.669 62.876  1.00 65.29  ? 601 ALA A CA  1 
ATOM   4118  C C   . ALA A 1 541 ? -88.065  -15.726 62.656  1.00 60.41  ? 601 ALA A C   1 
ATOM   4119  O O   . ALA A 1 541 ? -88.582  -15.025 61.751  1.00 52.63  ? 601 ALA A O   1 
ATOM   4120  C CB  . ALA A 1 541 ? -85.873  -16.950 62.449  1.00 77.02  ? 601 ALA A CB  1 
ATOM   4121  N N   . ALA A 1 542 ? -88.751  -16.526 63.479  1.00 61.94  ? 602 ALA A N   1 
ATOM   4122  C CA  . ALA A 1 542 ? -90.221  -16.691 63.465  1.00 62.27  ? 602 ALA A CA  1 
ATOM   4123  C C   . ALA A 1 542 ? -90.878  -15.302 63.541  1.00 57.94  ? 602 ALA A C   1 
ATOM   4124  O O   . ALA A 1 542 ? -91.771  -15.020 62.726  1.00 58.09  ? 602 ALA A O   1 
ATOM   4125  C CB  . ALA A 1 542 ? -90.652  -17.605 64.579  1.00 57.14  ? 602 ALA A CB  1 
ATOM   4126  N N   . LYS A 1 543 ? -90.398  -14.447 64.444  1.00 60.36  ? 603 LYS A N   1 
ATOM   4127  C CA  . LYS A 1 543 ? -90.909  -13.064 64.638  1.00 61.85  ? 603 LYS A CA  1 
ATOM   4128  C C   . LYS A 1 543 ? -90.619  -12.228 63.406  1.00 51.64  ? 603 LYS A C   1 
ATOM   4129  O O   . LYS A 1 543 ? -91.441  -11.362 63.086  1.00 56.90  ? 603 LYS A O   1 
ATOM   4130  C CB  . LYS A 1 543 ? -90.288  -12.382 65.861  1.00 70.29  ? 603 LYS A CB  1 
ATOM   4131  C CG  . LYS A 1 543 ? -90.914  -11.036 66.213  1.00 78.47  ? 603 LYS A CG  1 
ATOM   4132  C CD  . LYS A 1 543 ? -92.411  -11.030 66.519  1.00 84.70  ? 603 LYS A CD  1 
ATOM   4133  C CE  . LYS A 1 543 ? -92.869  -11.925 67.654  1.00 82.20  ? 603 LYS A CE  1 
ATOM   4134  N NZ  . LYS A 1 543 ? -94.312  -12.193 67.521  1.00 82.10  ? 603 LYS A NZ  1 
ATOM   4135  N N   . ALA A 1 544 ? -89.479  -12.472 62.767  1.00 64.33  ? 604 ALA A N   1 
ATOM   4136  C CA  . ALA A 1 544 ? -89.031  -11.723 61.570  1.00 68.97  ? 604 ALA A CA  1 
ATOM   4137  C C   . ALA A 1 544 ? -90.016  -12.008 60.427  1.00 69.77  ? 604 ALA A C   1 
ATOM   4138  O O   . ALA A 1 544 ? -90.442  -11.021 59.772  1.00 69.62  ? 604 ALA A O   1 
ATOM   4139  C CB  . ALA A 1 544 ? -87.606  -12.091 61.232  1.00 66.80  ? 604 ALA A CB  1 
ATOM   4140  N N   . TYR A 1 545 ? -90.365  -13.294 60.234  1.00 66.62  ? 605 TYR A N   1 
ATOM   4141  C CA  . TYR A 1 545 ? -91.351  -13.792 59.235  1.00 66.74  ? 605 TYR A CA  1 
ATOM   4142  C C   . TYR A 1 545 ? -92.743  -13.228 59.551  1.00 68.92  ? 605 TYR A C   1 
ATOM   4143  O O   . TYR A 1 545 ? -93.310  -12.583 58.671  1.00 73.80  ? 605 TYR A O   1 
ATOM   4144  C CB  . TYR A 1 545 ? -91.401  -15.322 59.221  1.00 69.98  ? 605 TYR A CB  1 
ATOM   4145  C CG  . TYR A 1 545 ? -90.218  -15.983 58.573  1.00 67.50  ? 605 TYR A CG  1 
ATOM   4146  C CD1 . TYR A 1 545 ? -89.838  -15.660 57.281  1.00 71.66  ? 605 TYR A CD1 1 
ATOM   4147  C CD2 . TYR A 1 545 ? -89.491  -16.951 59.241  1.00 71.42  ? 605 TYR A CD2 1 
ATOM   4148  C CE1 . TYR A 1 545 ? -88.749  -16.265 56.671  1.00 70.72  ? 605 TYR A CE1 1 
ATOM   4149  C CE2 . TYR A 1 545 ? -88.397  -17.567 58.643  1.00 75.59  ? 605 TYR A CE2 1 
ATOM   4150  C CZ  . TYR A 1 545 ? -88.023  -17.223 57.355  1.00 66.19  ? 605 TYR A CZ  1 
ATOM   4151  O OH  . TYR A 1 545 ? -86.957  -17.834 56.770  1.00 66.04  ? 605 TYR A OH  1 
ATOM   4152  N N   . GLU A 1 546 ? -93.260  -13.466 60.760  1.00 70.91  ? 606 GLU A N   1 
ATOM   4153  C CA  . GLU A 1 546 ? -94.545  -12.908 61.258  1.00 67.88  ? 606 GLU A CA  1 
ATOM   4154  C C   . GLU A 1 546 ? -94.611  -11.406 60.906  1.00 67.88  ? 606 GLU A C   1 
ATOM   4155  O O   . GLU A 1 546 ? -95.513  -11.015 60.167  1.00 69.56  ? 606 GLU A O   1 
ATOM   4156  C CB  . GLU A 1 546 ? -94.690  -13.171 62.761  1.00 78.52  ? 606 GLU A CB  1 
ATOM   4157  C CG  . GLU A 1 546 ? -96.140  -13.017 63.241  1.00 89.28  ? 606 GLU A CG  1 
ATOM   4158  C CD  . GLU A 1 546 ? -96.369  -12.901 64.741  1.00 95.56  ? 606 GLU A CD  1 
ATOM   4159  O OE1 . GLU A 1 546 ? -95.652  -13.596 65.503  1.00 97.69  ? 606 GLU A OE1 1 
ATOM   4160  O OE2 . GLU A 1 546 ? -97.237  -12.094 65.151  1.00 89.73  ? 606 GLU A OE2 1 
ATOM   4161  N N   . LEU A 1 547 ? -93.659  -10.584 61.353  1.00 64.73  ? 607 LEU A N   1 
ATOM   4162  C CA  . LEU A 1 547 ? -93.622  -9.135  61.019  1.00 61.80  ? 607 LEU A CA  1 
ATOM   4163  C C   . LEU A 1 547 ? -93.388  -8.877  59.521  1.00 60.41  ? 607 LEU A C   1 
ATOM   4164  O O   . LEU A 1 547 ? -93.364  -7.690  59.128  1.00 62.88  ? 607 LEU A O   1 
ATOM   4165  C CB  . LEU A 1 547 ? -92.490  -8.500  61.818  1.00 62.73  ? 607 LEU A CB  1 
ATOM   4166  C CG  . LEU A 1 547 ? -92.823  -8.177  63.260  1.00 72.71  ? 607 LEU A CG  1 
ATOM   4167  C CD1 . LEU A 1 547 ? -91.538  -7.934  64.051  1.00 81.40  ? 607 LEU A CD1 1 
ATOM   4168  C CD2 . LEU A 1 547 ? -93.728  -6.948  63.291  1.00 77.96  ? 607 LEU A CD2 1 
ATOM   4169  N N   . GLY A 1 548 ? -93.147  -9.922  58.732  1.00 61.52  ? 608 GLY A N   1 
ATOM   4170  C CA  . GLY A 1 548 ? -92.775  -9.824  57.304  1.00 66.12  ? 608 GLY A CA  1 
ATOM   4171  C C   . GLY A 1 548 ? -91.602  -8.889  57.071  1.00 76.79  ? 608 GLY A C   1 
ATOM   4172  O O   . GLY A 1 548 ? -91.753  -7.963  56.254  1.00 73.52  ? 608 GLY A O   1 
ATOM   4173  N N   . LEU A 1 549 ? -90.487  -9.090  57.794  1.00 78.90  ? 609 LEU A N   1 
ATOM   4174  C CA  . LEU A 1 549 ? -89.194  -8.389  57.574  1.00 63.78  ? 609 LEU A CA  1 
ATOM   4175  C C   . LEU A 1 549 ? -88.105  -9.384  57.133  1.00 63.84  ? 609 LEU A C   1 
ATOM   4176  O O   . LEU A 1 549 ? -87.003  -8.932  56.791  1.00 61.49  ? 609 LEU A O   1 
ATOM   4177  C CB  . LEU A 1 549 ? -88.822  -7.679  58.872  1.00 61.00  ? 609 LEU A CB  1 
ATOM   4178  C CG  . LEU A 1 549 ? -89.704  -6.475  59.222  1.00 61.48  ? 609 LEU A CG  1 
ATOM   4179  C CD1 . LEU A 1 549 ? -89.705  -6.186  60.712  1.00 59.63  ? 609 LEU A CD1 1 
ATOM   4180  C CD2 . LEU A 1 549 ? -89.251  -5.235  58.479  1.00 62.10  ? 609 LEU A CD2 1 
ATOM   4181  N N   . ALA A 1 550 ? -88.412  -10.688 57.110  1.00 66.83  ? 610 ALA A N   1 
ATOM   4182  C CA  . ALA A 1 550 ? -87.536  -11.790 56.638  1.00 63.25  ? 610 ALA A CA  1 
ATOM   4183  C C   . ALA A 1 550 ? -87.533  -11.784 55.116  1.00 71.60  ? 610 ALA A C   1 
ATOM   4184  O O   . ALA A 1 550 ? -88.561  -11.344 54.558  1.00 77.65  ? 610 ALA A O   1 
ATOM   4185  C CB  . ALA A 1 550 ? -88.041  -13.119 57.143  1.00 63.88  ? 610 ALA A CB  1 
ATOM   4186  N N   . THR A 1 551 ? -86.433  -12.238 54.484  1.00 74.41  ? 611 THR A N   1 
ATOM   4187  C CA  . THR A 1 551 ? -86.289  -12.366 52.999  1.00 65.62  ? 611 THR A CA  1 
ATOM   4188  C C   . THR A 1 551 ? -85.870  -13.782 52.601  1.00 61.64  ? 611 THR A C   1 
ATOM   4189  O O   . THR A 1 551 ? -85.750  -13.992 51.419  1.00 70.47  ? 611 THR A O   1 
ATOM   4190  C CB  . THR A 1 551 ? -85.281  -11.380 52.385  1.00 59.16  ? 611 THR A CB  1 
ATOM   4191  O OG1 . THR A 1 551 ? -83.965  -11.830 52.708  1.00 66.61  ? 611 THR A OG1 1 
ATOM   4192  C CG2 . THR A 1 551 ? -85.482  -9.944  52.824  1.00 56.38  ? 611 THR A CG2 1 
ATOM   4193  N N   . ARG A 1 552 ? -85.628  -14.702 53.536  1.00 65.15  ? 612 ARG A N   1 
ATOM   4194  C CA  . ARG A 1 552 ? -85.376  -16.125 53.198  1.00 71.34  ? 612 ARG A CA  1 
ATOM   4195  C C   . ARG A 1 552 ? -86.725  -16.844 53.160  1.00 78.66  ? 612 ARG A C   1 
ATOM   4196  O O   . ARG A 1 552 ? -87.027  -17.556 54.150  1.00 87.00  ? 612 ARG A O   1 
ATOM   4197  C CB  . ARG A 1 552 ? -84.424  -16.770 54.208  1.00 78.27  ? 612 ARG A CB  1 
ATOM   4198  C CG  . ARG A 1 552 ? -83.720  -18.007 53.691  1.00 95.42  ? 612 ARG A CG  1 
ATOM   4199  C CD  . ARG A 1 552 ? -84.690  -19.158 53.512  1.00 101.55 ? 612 ARG A CD  1 
ATOM   4200  N NE  . ARG A 1 552 ? -84.029  -20.440 53.337  1.00 99.43  ? 612 ARG A NE  1 
ATOM   4201  C CZ  . ARG A 1 552 ? -84.640  -21.569 53.008  1.00 95.34  ? 612 ARG A CZ  1 
ATOM   4202  N NH1 . ARG A 1 552 ? -85.951  -21.584 52.807  1.00 90.43  ? 612 ARG A NH1 1 
ATOM   4203  N NH2 . ARG A 1 552 ? -83.928  -22.676 52.875  1.00 97.40  ? 612 ARG A NH2 1 
ATOM   4204  N N   . LEU A 1 553 ? -87.508  -16.647 52.088  1.00 72.22  ? 613 LEU A N   1 
ATOM   4205  C CA  . LEU A 1 553 ? -88.862  -17.242 51.925  1.00 69.49  ? 613 LEU A CA  1 
ATOM   4206  C C   . LEU A 1 553 ? -88.710  -18.503 51.068  1.00 72.37  ? 613 LEU A C   1 
ATOM   4207  O O   . LEU A 1 553 ? -87.833  -18.569 50.213  1.00 74.00  ? 613 LEU A O   1 
ATOM   4208  C CB  . LEU A 1 553 ? -89.808  -16.228 51.263  1.00 75.93  ? 613 LEU A CB  1 
ATOM   4209  C CG  . LEU A 1 553 ? -90.352  -15.079 52.109  1.00 76.29  ? 613 LEU A CG  1 
ATOM   4210  C CD1 . LEU A 1 553 ? -90.890  -15.579 53.444  1.00 82.00  ? 613 LEU A CD1 1 
ATOM   4211  C CD2 . LEU A 1 553 ? -89.302  -14.004 52.296  1.00 69.34  ? 613 LEU A CD2 1 
ATOM   4212  N N   . PRO A 1 554 ? -89.528  -19.566 51.250  1.00 78.65  ? 614 PRO A N   1 
ATOM   4213  C CA  . PRO A 1 554 ? -90.454  -19.691 52.374  1.00 80.52  ? 614 PRO A CA  1 
ATOM   4214  C C   . PRO A 1 554 ? -89.713  -20.020 53.665  1.00 77.68  ? 614 PRO A C   1 
ATOM   4215  O O   . PRO A 1 554 ? -88.580  -20.496 53.608  1.00 81.19  ? 614 PRO A O   1 
ATOM   4216  C CB  . PRO A 1 554 ? -91.379  -20.868 51.996  1.00 77.00  ? 614 PRO A CB  1 
ATOM   4217  C CG  . PRO A 1 554 ? -91.130  -21.126 50.534  1.00 82.50  ? 614 PRO A CG  1 
ATOM   4218  C CD  . PRO A 1 554 ? -89.709  -20.652 50.277  1.00 79.48  ? 614 PRO A CD  1 
ATOM   4219  N N   . PRO A 1 555 ? -90.318  -19.782 54.858  1.00 71.92  ? 615 PRO A N   1 
ATOM   4220  C CA  . PRO A 1 555 ? -89.697  -20.154 56.128  1.00 68.95  ? 615 PRO A CA  1 
ATOM   4221  C C   . PRO A 1 555 ? -89.566  -21.669 56.209  1.00 61.39  ? 615 PRO A C   1 
ATOM   4222  O O   . PRO A 1 555 ? -90.384  -22.411 55.691  1.00 62.57  ? 615 PRO A O   1 
ATOM   4223  C CB  . PRO A 1 555 ? -90.644  -19.622 57.214  1.00 71.94  ? 615 PRO A CB  1 
ATOM   4224  C CG  . PRO A 1 555 ? -91.989  -19.441 56.504  1.00 73.31  ? 615 PRO A CG  1 
ATOM   4225  C CD  . PRO A 1 555 ? -91.640  -19.163 55.054  1.00 72.77  ? 615 PRO A CD  1 
ATOM   4226  N N   . PRO A 1 556 ? -88.490  -22.193 56.805  1.00 62.09  ? 616 PRO A N   1 
ATOM   4227  C CA  . PRO A 1 556 ? -88.370  -23.641 56.975  1.00 65.36  ? 616 PRO A CA  1 
ATOM   4228  C C   . PRO A 1 556 ? -89.484  -24.154 57.882  1.00 63.20  ? 616 PRO A C   1 
ATOM   4229  O O   . PRO A 1 556 ? -89.993  -23.353 58.632  1.00 53.31  ? 616 PRO A O   1 
ATOM   4230  C CB  . PRO A 1 556 ? -87.007  -23.830 57.639  1.00 69.45  ? 616 PRO A CB  1 
ATOM   4231  C CG  . PRO A 1 556 ? -86.260  -22.537 57.300  1.00 70.62  ? 616 PRO A CG  1 
ATOM   4232  C CD  . PRO A 1 556 ? -87.311  -21.445 57.259  1.00 63.02  ? 616 PRO A CD  1 
ATOM   4233  N N   . SER A 1 557 ? -89.826  -25.442 57.780  1.00 71.49  ? 617 SER A N   1 
ATOM   4234  C CA  . SER A 1 557 ? -90.867  -26.083 58.626  1.00 72.86  ? 617 SER A CA  1 
ATOM   4235  C C   . SER A 1 557 ? -90.429  -25.980 60.086  1.00 70.77  ? 617 SER A C   1 
ATOM   4236  O O   . SER A 1 557 ? -91.209  -25.415 60.874  1.00 73.69  ? 617 SER A O   1 
ATOM   4237  C CB  . SER A 1 557 ? -91.135  -27.521 58.237  1.00 80.96  ? 617 SER A CB  1 
ATOM   4238  O OG  . SER A 1 557 ? -90.014  -28.349 58.531  1.00 81.51  ? 617 SER A OG  1 
ATOM   4239  N N   . ASP A 1 558 ? -89.198  -26.434 60.399  1.00 76.29  ? 618 ASP A N   1 
ATOM   4240  C CA  . ASP A 1 558 ? -88.644  -26.632 61.775  1.00 68.18  ? 618 ASP A CA  1 
ATOM   4241  C C   . ASP A 1 558 ? -87.499  -25.637 62.035  1.00 57.73  ? 618 ASP A C   1 
ATOM   4242  O O   . ASP A 1 558 ? -86.358  -26.031 61.902  1.00 59.83  ? 618 ASP A O   1 
ATOM   4243  C CB  . ASP A 1 558 ? -88.187  -28.085 61.952  1.00 62.37  ? 618 ASP A CB  1 
ATOM   4244  C CG  . ASP A 1 558 ? -87.778  -28.469 63.363  1.00 67.02  ? 618 ASP A CG  1 
ATOM   4245  O OD1 . ASP A 1 558 ? -87.637  -27.562 64.203  1.00 72.27  ? 618 ASP A OD1 1 
ATOM   4246  O OD2 . ASP A 1 558 ? -87.604  -29.683 63.614  1.00 73.27  ? 618 ASP A OD2 1 
ATOM   4247  N N   . LEU A 1 559 ? -87.805  -24.408 62.445  1.00 55.72  ? 619 LEU A N   1 
ATOM   4248  C CA  . LEU A 1 559 ? -86.834  -23.284 62.551  1.00 60.17  ? 619 LEU A CA  1 
ATOM   4249  C C   . LEU A 1 559 ? -85.712  -23.592 63.559  1.00 65.14  ? 619 LEU A C   1 
ATOM   4250  O O   . LEU A 1 559 ? -84.650  -22.989 63.448  1.00 71.87  ? 619 LEU A O   1 
ATOM   4251  C CB  . LEU A 1 559 ? -87.592  -22.018 62.960  1.00 60.59  ? 619 LEU A CB  1 
ATOM   4252  C CG  . LEU A 1 559 ? -88.047  -21.103 61.827  1.00 56.11  ? 619 LEU A CG  1 
ATOM   4253  C CD1 . LEU A 1 559 ? -88.686  -19.817 62.365  1.00 59.52  ? 619 LEU A CD1 1 
ATOM   4254  C CD2 . LEU A 1 559 ? -86.868  -20.760 60.951  1.00 60.46  ? 619 LEU A CD2 1 
ATOM   4255  N N   . VAL A 1 560 ? -85.931  -24.462 64.538  1.00 71.72  ? 620 VAL A N   1 
ATOM   4256  C CA  . VAL A 1 560 ? -84.888  -24.864 65.531  1.00 73.70  ? 620 VAL A CA  1 
ATOM   4257  C C   . VAL A 1 560 ? -83.853  -25.787 64.858  1.00 73.86  ? 620 VAL A C   1 
ATOM   4258  O O   . VAL A 1 560 ? -82.642  -25.464 64.927  1.00 84.23  ? 620 VAL A O   1 
ATOM   4259  C CB  . VAL A 1 560 ? -85.530  -25.498 66.779  1.00 73.47  ? 620 VAL A CB  1 
ATOM   4260  C CG1 . VAL A 1 560 ? -84.541  -26.359 67.575  1.00 74.96  ? 620 VAL A CG1 1 
ATOM   4261  C CG2 . VAL A 1 560 ? -86.181  -24.419 67.639  1.00 74.71  ? 620 VAL A CG2 1 
ATOM   4262  N N   . LYS A 1 561 ? -84.285  -26.883 64.222  1.00 76.56  ? 621 LYS A N   1 
ATOM   4263  C CA  . LYS A 1 561 ? -83.373  -27.858 63.558  1.00 75.19  ? 621 LYS A CA  1 
ATOM   4264  C C   . LYS A 1 561 ? -82.624  -27.166 62.405  1.00 62.40  ? 621 LYS A C   1 
ATOM   4265  O O   . LYS A 1 561 ? -81.472  -27.536 62.142  1.00 58.77  ? 621 LYS A O   1 
ATOM   4266  C CB  . LYS A 1 561 ? -84.163  -29.083 63.078  1.00 90.87  ? 621 LYS A CB  1 
ATOM   4267  C CG  . LYS A 1 561 ? -83.347  -30.197 62.433  1.00 100.92 ? 621 LYS A CG  1 
ATOM   4268  C CD  . LYS A 1 561 ? -84.084  -30.924 61.309  1.00 110.99 ? 621 LYS A CD  1 
ATOM   4269  C CE  . LYS A 1 561 ? -83.151  -31.574 60.301  1.00 119.18 ? 621 LYS A CE  1 
ATOM   4270  N NZ  . LYS A 1 561 ? -82.524  -32.814 60.830  1.00 119.35 ? 621 LYS A NZ  1 
ATOM   4271  N N   . TYR A 1 562 ? -83.231  -26.188 61.736  1.00 58.82  ? 622 TYR A N   1 
ATOM   4272  C CA  . TYR A 1 562 ? -82.575  -25.394 60.660  1.00 59.57  ? 622 TYR A CA  1 
ATOM   4273  C C   . TYR A 1 562 ? -81.448  -24.551 61.278  1.00 61.05  ? 622 TYR A C   1 
ATOM   4274  O O   . TYR A 1 562 ? -80.321  -24.590 60.768  1.00 74.41  ? 622 TYR A O   1 
ATOM   4275  C CB  . TYR A 1 562 ? -83.602  -24.552 59.898  1.00 55.28  ? 622 TYR A CB  1 
ATOM   4276  C CG  . TYR A 1 562 ? -83.061  -23.526 58.934  1.00 56.16  ? 622 TYR A CG  1 
ATOM   4277  C CD1 . TYR A 1 562 ? -82.437  -23.896 57.746  1.00 56.97  ? 622 TYR A CD1 1 
ATOM   4278  C CD2 . TYR A 1 562 ? -83.200  -22.167 59.207  1.00 61.32  ? 622 TYR A CD2 1 
ATOM   4279  C CE1 . TYR A 1 562 ? -81.951  -22.941 56.860  1.00 61.91  ? 622 TYR A CE1 1 
ATOM   4280  C CE2 . TYR A 1 562 ? -82.720  -21.198 58.335  1.00 62.90  ? 622 TYR A CE2 1 
ATOM   4281  C CZ  . TYR A 1 562 ? -82.085  -21.587 57.169  1.00 67.05  ? 622 TYR A CZ  1 
ATOM   4282  O OH  . TYR A 1 562 ? -81.629  -20.573 56.377  1.00 63.24  ? 622 TYR A OH  1 
ATOM   4283  N N   . ALA A 1 563 ? -81.748  -23.818 62.347  1.00 54.65  ? 623 ALA A N   1 
ATOM   4284  C CA  . ALA A 1 563 ? -80.792  -22.950 63.061  1.00 55.03  ? 623 ALA A CA  1 
ATOM   4285  C C   . ALA A 1 563 ? -79.591  -23.791 63.519  1.00 55.71  ? 623 ALA A C   1 
ATOM   4286  O O   . ALA A 1 563 ? -78.459  -23.286 63.374  1.00 50.23  ? 623 ALA A O   1 
ATOM   4287  C CB  . ALA A 1 563 ? -81.475  -22.261 64.211  1.00 55.17  ? 623 ALA A CB  1 
ATOM   4288  N N   . GLU A 1 564 ? -79.812  -25.014 64.027  1.00 64.62  ? 624 GLU A N   1 
ATOM   4289  C CA  . GLU A 1 564 ? -78.717  -25.927 64.489  1.00 69.40  ? 624 GLU A CA  1 
ATOM   4290  C C   . GLU A 1 564 ? -77.881  -26.426 63.301  1.00 70.33  ? 624 GLU A C   1 
ATOM   4291  O O   . GLU A 1 564 ? -76.687  -26.652 63.508  1.00 75.06  ? 624 GLU A O   1 
ATOM   4292  C CB  . GLU A 1 564 ? -79.238  -27.148 65.239  1.00 64.24  ? 624 GLU A CB  1 
ATOM   4293  C CG  . GLU A 1 564 ? -79.794  -26.810 66.607  1.00 69.47  ? 624 GLU A CG  1 
ATOM   4294  C CD  . GLU A 1 564 ? -80.645  -27.911 67.220  1.00 76.89  ? 624 GLU A CD  1 
ATOM   4295  O OE1 . GLU A 1 564 ? -81.001  -28.847 66.497  1.00 86.07  ? 624 GLU A OE1 1 
ATOM   4296  O OE2 . GLU A 1 564 ? -80.983  -27.811 68.401  1.00 95.86  ? 624 GLU A OE2 1 
ATOM   4297  N N   . ASN A 1 565 ? -78.483  -26.573 62.121  1.00 70.55  ? 625 ASN A N   1 
ATOM   4298  C CA  . ASN A 1 565 ? -77.799  -27.050 60.887  1.00 64.94  ? 625 ASN A CA  1 
ATOM   4299  C C   . ASN A 1 565 ? -77.003  -25.910 60.253  1.00 61.93  ? 625 ASN A C   1 
ATOM   4300  O O   . ASN A 1 565 ? -76.064  -26.226 59.549  1.00 64.82  ? 625 ASN A O   1 
ATOM   4301  C CB  . ASN A 1 565 ? -78.772  -27.670 59.873  1.00 62.26  ? 625 ASN A CB  1 
ATOM   4302  C CG  . ASN A 1 565 ? -79.224  -29.055 60.279  1.00 65.95  ? 625 ASN A CG  1 
ATOM   4303  O OD1 . ASN A 1 565 ? -78.546  -29.719 61.057  1.00 67.73  ? 625 ASN A OD1 1 
ATOM   4304  N ND2 . ASN A 1 565 ? -80.373  -29.485 59.791  1.00 58.64  ? 625 ASN A ND2 1 
ATOM   4305  N N   . CYS A 1 566 ? -77.344  -24.645 60.505  1.00 63.06  ? 626 CYS A N   1 
ATOM   4306  C CA  . CYS A 1 566 ? -76.593  -23.462 59.995  1.00 62.71  ? 626 CYS A CA  1 
ATOM   4307  C C   . CYS A 1 566 ? -75.360  -23.161 60.860  1.00 63.09  ? 626 CYS A C   1 
ATOM   4308  O O   . CYS A 1 566 ? -74.684  -22.158 60.558  1.00 63.12  ? 626 CYS A O   1 
ATOM   4309  C CB  . CYS A 1 566 ? -77.439  -22.194 60.014  1.00 68.59  ? 626 CYS A CB  1 
ATOM   4310  S SG  . CYS A 1 566 ? -78.816  -22.222 58.841  1.00 65.33  ? 626 CYS A SG  1 
ATOM   4311  N N   . MET A 1 567 ? -75.108  -23.936 61.918  1.00 60.66  ? 627 MET A N   1 
ATOM   4312  C CA  . MET A 1 567 ? -74.157  -23.534 62.991  1.00 61.53  ? 627 MET A CA  1 
ATOM   4313  C C   . MET A 1 567 ? -72.768  -24.077 62.664  1.00 55.14  ? 627 MET A C   1 
ATOM   4314  O O   . MET A 1 567 ? -72.631  -25.293 62.403  1.00 61.40  ? 627 MET A O   1 
ATOM   4315  C CB  . MET A 1 567 ? -74.582  -24.025 64.385  1.00 65.20  ? 627 MET A CB  1 
ATOM   4316  C CG  . MET A 1 567 ? -75.429  -23.040 65.159  1.00 64.20  ? 627 MET A CG  1 
ATOM   4317  S SD  . MET A 1 567 ? -75.968  -23.781 66.691  1.00 68.49  ? 627 MET A SD  1 
ATOM   4318  C CE  . MET A 1 567 ? -76.423  -22.354 67.666  1.00 68.75  ? 627 MET A CE  1 
ATOM   4319  N N   . TYR A 1 568 ? -71.795  -23.175 62.672  1.00 57.48  ? 628 TYR A N   1 
ATOM   4320  C CA  . TYR A 1 568 ? -70.349  -23.462 62.530  1.00 54.57  ? 628 TYR A CA  1 
ATOM   4321  C C   . TYR A 1 568 ? -69.959  -24.523 63.550  1.00 50.96  ? 628 TYR A C   1 
ATOM   4322  O O   . TYR A 1 568 ? -70.357  -24.431 64.684  1.00 58.62  ? 628 TYR A O   1 
ATOM   4323  C CB  . TYR A 1 568 ? -69.523  -22.191 62.690  1.00 47.72  ? 628 TYR A CB  1 
ATOM   4324  C CG  . TYR A 1 568 ? -68.041  -22.423 62.793  1.00 42.39  ? 628 TYR A CG  1 
ATOM   4325  C CD1 . TYR A 1 568 ? -67.421  -22.570 64.025  1.00 45.79  ? 628 TYR A CD1 1 
ATOM   4326  C CD2 . TYR A 1 568 ? -67.253  -22.492 61.662  1.00 39.99  ? 628 TYR A CD2 1 
ATOM   4327  C CE1 . TYR A 1 568 ? -66.055  -22.776 64.135  1.00 43.73  ? 628 TYR A CE1 1 
ATOM   4328  C CE2 . TYR A 1 568 ? -65.887  -22.681 61.744  1.00 42.02  ? 628 TYR A CE2 1 
ATOM   4329  C CZ  . TYR A 1 568 ? -65.288  -22.787 62.988  1.00 45.55  ? 628 TYR A CZ  1 
ATOM   4330  O OH  . TYR A 1 568 ? -63.945  -22.940 63.084  1.00 55.34  ? 628 TYR A OH  1 
ATOM   4331  N N   . THR A 1 569 ? -69.241  -25.533 63.102  1.00 49.59  ? 629 THR A N   1 
ATOM   4332  C CA  . THR A 1 569 ? -68.584  -26.521 63.973  1.00 54.20  ? 629 THR A CA  1 
ATOM   4333  C C   . THR A 1 569 ? -67.089  -26.370 63.700  1.00 59.53  ? 629 THR A C   1 
ATOM   4334  O O   . THR A 1 569 ? -66.639  -26.228 62.565  1.00 52.60  ? 629 THR A O   1 
ATOM   4335  C CB  . THR A 1 569 ? -69.126  -27.940 63.744  1.00 59.22  ? 629 THR A CB  1 
ATOM   4336  O OG1 . THR A 1 569 ? -68.195  -28.815 64.376  1.00 65.27  ? 629 THR A OG1 1 
ATOM   4337  C CG2 . THR A 1 569 ? -69.237  -28.330 62.287  1.00 64.33  ? 629 THR A CG2 1 
ATOM   4338  N N   . PRO A 1 570 ? -66.252  -26.342 64.747  1.00 58.11  ? 630 PRO A N   1 
ATOM   4339  C CA  . PRO A 1 570 ? -64.820  -26.192 64.557  1.00 54.41  ? 630 PRO A CA  1 
ATOM   4340  C C   . PRO A 1 570 ? -64.042  -27.515 64.486  1.00 51.57  ? 630 PRO A C   1 
ATOM   4341  O O   . PRO A 1 570 ? -62.826  -27.478 64.553  1.00 51.05  ? 630 PRO A O   1 
ATOM   4342  C CB  . PRO A 1 570 ? -64.498  -25.388 65.815  1.00 67.01  ? 630 PRO A CB  1 
ATOM   4343  C CG  . PRO A 1 570 ? -65.447  -25.915 66.880  1.00 67.63  ? 630 PRO A CG  1 
ATOM   4344  C CD  . PRO A 1 570 ? -66.650  -26.440 66.153  1.00 63.20  ? 630 PRO A CD  1 
ATOM   4345  N N   . VAL A 1 571 ? -64.714  -28.654 64.325  1.00 47.43  ? 631 VAL A N   1 
ATOM   4346  C CA  . VAL A 1 571 ? -63.989  -29.939 64.079  1.00 52.11  ? 631 VAL A CA  1 
ATOM   4347  C C   . VAL A 1 571 ? -63.101  -29.782 62.829  1.00 49.75  ? 631 VAL A C   1 
ATOM   4348  O O   . VAL A 1 571 ? -63.491  -29.149 61.897  1.00 51.82  ? 631 VAL A O   1 
ATOM   4349  C CB  . VAL A 1 571 ? -64.960  -31.134 64.003  1.00 53.03  ? 631 VAL A CB  1 
ATOM   4350  C CG1 . VAL A 1 571 ? -64.298  -32.369 63.412  1.00 56.64  ? 631 VAL A CG1 1 
ATOM   4351  C CG2 . VAL A 1 571 ? -65.523  -31.467 65.383  1.00 52.85  ? 631 VAL A CG2 1 
ATOM   4352  N N   . TYR A 1 572 ? -61.896  -30.343 62.811  1.00 58.14  ? 632 TYR A N   1 
ATOM   4353  C CA  . TYR A 1 572 ? -60.958  -30.309 61.652  1.00 52.33  ? 632 TYR A CA  1 
ATOM   4354  C C   . TYR A 1 572 ? -61.570  -31.192 60.553  1.00 64.57  ? 632 TYR A C   1 
ATOM   4355  O O   . TYR A 1 572 ? -61.950  -32.405 60.849  1.00 67.59  ? 632 TYR A O   1 
ATOM   4356  C CB  . TYR A 1 572 ? -59.579  -30.902 61.969  1.00 50.14  ? 632 TYR A CB  1 
ATOM   4357  C CG  . TYR A 1 572 ? -58.619  -30.113 62.823  1.00 47.27  ? 632 TYR A CG  1 
ATOM   4358  C CD1 . TYR A 1 572 ? -58.490  -28.728 62.688  1.00 46.63  ? 632 TYR A CD1 1 
ATOM   4359  C CD2 . TYR A 1 572 ? -57.812  -30.758 63.751  1.00 46.06  ? 632 TYR A CD2 1 
ATOM   4360  C CE1 . TYR A 1 572 ? -57.618  -27.992 63.478  1.00 39.37  ? 632 TYR A CE1 1 
ATOM   4361  C CE2 . TYR A 1 572 ? -56.910  -30.040 64.526  1.00 48.89  ? 632 TYR A CE2 1 
ATOM   4362  C CZ  . TYR A 1 572 ? -56.810  -28.661 64.384  1.00 41.95  ? 632 TYR A CZ  1 
ATOM   4363  O OH  . TYR A 1 572 ? -55.912  -28.000 65.162  1.00 38.49  ? 632 TYR A OH  1 
ATOM   4364  N N   . ARG A 1 573 ? -61.755  -30.648 59.343  1.00 81.72  ? 633 ARG A N   1 
ATOM   4365  C CA  . ARG A 1 573 ? -62.001  -31.508 58.152  1.00 98.34  ? 633 ARG A CA  1 
ATOM   4366  C C   . ARG A 1 573 ? -60.642  -31.715 57.488  1.00 76.76  ? 633 ARG A C   1 
ATOM   4367  O O   . ARG A 1 573 ? -59.687  -31.021 57.831  1.00 59.45  ? 633 ARG A O   1 
ATOM   4368  C CB  . ARG A 1 573 ? -63.162  -31.052 57.248  1.00 125.00 ? 633 ARG A CB  1 
ATOM   4369  C CG  . ARG A 1 573 ? -64.414  -31.926 57.401  1.00 137.00 ? 633 ARG A CG  1 
ATOM   4370  C CD  . ARG A 1 573 ? -64.254  -33.338 56.818  1.00 145.33 ? 633 ARG A CD  1 
ATOM   4371  N NE  . ARG A 1 573 ? -65.403  -33.782 56.027  1.00 162.91 ? 633 ARG A NE  1 
ATOM   4372  C CZ  . ARG A 1 573 ? -65.822  -33.214 54.889  1.00 165.10 ? 633 ARG A CZ  1 
ATOM   4373  N NH1 . ARG A 1 573 ? -66.875  -33.708 54.256  1.00 161.38 ? 633 ARG A NH1 1 
ATOM   4374  N NH2 . ARG A 1 573 ? -65.207  -32.151 54.388  1.00 153.67 ? 633 ARG A NH2 1 
ATOM   4375  N N   . ASN A 1 574 ? -60.577  -32.724 56.616  1.00 81.15  ? 634 ASN A N   1 
ATOM   4376  C CA  . ASN A 1 574 ? -59.347  -33.233 55.967  1.00 87.47  ? 634 ASN A CA  1 
ATOM   4377  C C   . ASN A 1 574 ? -59.148  -32.548 54.606  1.00 89.64  ? 634 ASN A C   1 
ATOM   4378  O O   . ASN A 1 574 ? -60.124  -32.334 53.869  1.00 94.06  ? 634 ASN A O   1 
ATOM   4379  C CB  . ASN A 1 574 ? -59.365  -34.755 55.815  1.00 79.10  ? 634 ASN A CB  1 
ATOM   4380  C CG  . ASN A 1 574 ? -59.681  -35.473 57.108  1.00 76.73  ? 634 ASN A CG  1 
ATOM   4381  O OD1 . ASN A 1 574 ? -60.855  -35.579 57.449  1.00 71.47  ? 634 ASN A OD1 1 
ATOM   4382  N ND2 . ASN A 1 574 ? -58.662  -35.955 57.819  1.00 75.30  ? 634 ASN A ND2 1 
ATOM   4383  N N   . TYR A 1 575 ? -57.892  -32.218 54.321  1.00 81.29  ? 635 TYR A N   1 
ATOM   4384  C CA  . TYR A 1 575 ? -57.424  -31.585 53.065  1.00 77.92  ? 635 TYR A CA  1 
ATOM   4385  C C   . TYR A 1 575 ? -56.697  -32.587 52.152  1.00 86.33  ? 635 TYR A C   1 
ATOM   4386  O O   . TYR A 1 575 ? -56.079  -33.541 52.640  1.00 88.43  ? 635 TYR A O   1 
ATOM   4387  C CB  . TYR A 1 575 ? -56.548  -30.380 53.399  1.00 75.16  ? 635 TYR A CB  1 
ATOM   4388  C CG  . TYR A 1 575 ? -57.161  -29.382 54.356  1.00 69.13  ? 635 TYR A CG  1 
ATOM   4389  C CD1 . TYR A 1 575 ? -57.093  -29.579 55.719  1.00 64.68  ? 635 TYR A CD1 1 
ATOM   4390  C CD2 . TYR A 1 575 ? -57.803  -28.238 53.911  1.00 68.85  ? 635 TYR A CD2 1 
ATOM   4391  C CE1 . TYR A 1 575 ? -57.612  -28.657 56.609  1.00 64.71  ? 635 TYR A CE1 1 
ATOM   4392  C CE2 . TYR A 1 575 ? -58.352  -27.319 54.786  1.00 58.16  ? 635 TYR A CE2 1 
ATOM   4393  C CZ  . TYR A 1 575 ? -58.242  -27.521 56.138  1.00 62.67  ? 635 TYR A CZ  1 
ATOM   4394  O OH  . TYR A 1 575 ? -58.837  -26.629 56.970  1.00 72.41  ? 635 TYR A OH  1 
ATOM   4395  N N   . ARG A 1 576 ? -56.779  -32.363 50.837  1.00 102.14 ? 636 ARG A N   1 
ATOM   4396  C CA  . ARG A 1 576 ? -56.057  -33.135 49.785  1.00 110.86 ? 636 ARG A CA  1 
ATOM   4397  C C   . ARG A 1 576 ? -54.601  -33.378 50.231  1.00 115.00 ? 636 ARG A C   1 
ATOM   4398  O O   . ARG A 1 576 ? -53.606  -33.454 49.499  1.00 100.79 ? 636 ARG A O   1 
ATOM   4399  C CB  . ARG A 1 576 ? -56.124  -32.369 48.460  1.00 114.34 ? 636 ARG A CB  1 
ATOM   4400  C CG  . ARG A 1 576 ? -57.521  -32.236 47.862  1.00 114.96 ? 636 ARG A CG  1 
ATOM   4401  C CD  . ARG A 1 576 ? -57.773  -33.158 46.677  1.00 124.59 ? 636 ARG A CD  1 
ATOM   4402  N NE  . ARG A 1 576 ? -59.180  -33.524 46.633  1.00 136.12 ? 636 ARG A NE  1 
ATOM   4403  C CZ  . ARG A 1 576 ? -59.703  -34.697 47.017  1.00 149.18 ? 636 ARG A CZ  1 
ATOM   4404  N NH1 . ARG A 1 576 ? -58.938  -35.693 47.451  1.00 133.44 ? 636 ARG A NH1 1 
ATOM   4405  N NH2 . ARG A 1 576 ? -61.015  -34.872 46.948  1.00 164.79 ? 636 ARG A NH2 1 
ATOM   4406  N N   . GLU B 1 24  ? -34.688  -35.500 35.611  1.00 138.57 ? 84  GLU B N   1 
ATOM   4407  C CA  . GLU B 1 24  ? -34.238  -36.672 36.419  1.00 144.48 ? 84  GLU B CA  1 
ATOM   4408  C C   . GLU B 1 24  ? -34.065  -36.242 37.888  1.00 141.17 ? 84  GLU B C   1 
ATOM   4409  O O   . GLU B 1 24  ? -34.320  -37.076 38.779  1.00 128.75 ? 84  GLU B O   1 
ATOM   4410  C CB  . GLU B 1 24  ? -32.976  -37.283 35.789  1.00 148.18 ? 84  GLU B CB  1 
ATOM   4411  C CG  . GLU B 1 24  ? -31.647  -36.806 36.373  1.00 145.87 ? 84  GLU B CG  1 
ATOM   4412  C CD  . GLU B 1 24  ? -31.126  -35.456 35.899  1.00 145.72 ? 84  GLU B CD  1 
ATOM   4413  O OE1 . GLU B 1 24  ? -31.838  -34.802 35.126  1.00 154.77 ? 84  GLU B OE1 1 
ATOM   4414  O OE2 . GLU B 1 24  ? -30.020  -35.057 36.313  1.00 120.90 ? 84  GLU B OE2 1 
ATOM   4415  N N   . LEU B 1 25  ? -33.632  -35.002 38.127  1.00 156.95 ? 85  LEU B N   1 
ATOM   4416  C CA  . LEU B 1 25  ? -33.583  -34.392 39.485  1.00 148.14 ? 85  LEU B CA  1 
ATOM   4417  C C   . LEU B 1 25  ? -35.033  -34.225 39.953  1.00 144.57 ? 85  LEU B C   1 
ATOM   4418  O O   . LEU B 1 25  ? -35.827  -33.573 39.273  1.00 141.18 ? 85  LEU B O   1 
ATOM   4419  C CB  . LEU B 1 25  ? -32.899  -33.006 39.435  1.00 139.35 ? 85  LEU B CB  1 
ATOM   4420  C CG  . LEU B 1 25  ? -31.367  -32.897 39.370  1.00 125.99 ? 85  LEU B CG  1 
ATOM   4421  C CD1 . LEU B 1 25  ? -30.865  -32.746 37.934  1.00 104.57 ? 85  LEU B CD1 1 
ATOM   4422  C CD2 . LEU B 1 25  ? -30.877  -31.711 40.202  1.00 115.54 ? 85  LEU B CD2 1 
ATOM   4423  N N   . PRO B 1 26  ? -35.464  -34.722 41.139  1.00 157.84 ? 86  PRO B N   1 
ATOM   4424  C CA  . PRO B 1 26  ? -36.655  -34.136 41.774  1.00 142.72 ? 86  PRO B CA  1 
ATOM   4425  C C   . PRO B 1 26  ? -36.431  -32.613 41.909  1.00 122.13 ? 86  PRO B C   1 
ATOM   4426  O O   . PRO B 1 26  ? -35.339  -32.224 42.261  1.00 165.28 ? 86  PRO B O   1 
ATOM   4427  C CB  . PRO B 1 26  ? -36.764  -34.859 43.132  1.00 162.00 ? 86  PRO B CB  1 
ATOM   4428  C CG  . PRO B 1 26  ? -35.422  -35.592 43.337  1.00 165.64 ? 86  PRO B CG  1 
ATOM   4429  C CD  . PRO B 1 26  ? -34.824  -35.783 41.951  1.00 166.48 ? 86  PRO B CD  1 
ATOM   4430  N N   . VAL B 1 27  ? -37.396  -31.760 41.608  1.00 89.75  ? 87  VAL B N   1 
ATOM   4431  C CA  . VAL B 1 27  ? -37.220  -30.281 41.812  1.00 81.36  ? 87  VAL B CA  1 
ATOM   4432  C C   . VAL B 1 27  ? -38.562  -29.672 42.228  1.00 76.99  ? 87  VAL B C   1 
ATOM   4433  O O   . VAL B 1 27  ? -39.613  -30.249 41.928  1.00 81.77  ? 87  VAL B O   1 
ATOM   4434  C CB  . VAL B 1 27  ? -36.590  -29.558 40.598  1.00 83.78  ? 87  VAL B CB  1 
ATOM   4435  C CG1 . VAL B 1 27  ? -37.281  -29.912 39.292  1.00 100.15 ? 87  VAL B CG1 1 
ATOM   4436  C CG2 . VAL B 1 27  ? -36.493  -28.045 40.754  1.00 85.62  ? 87  VAL B CG2 1 
ATOM   4437  N N   . MET B 1 28  ? -38.523  -28.566 42.961  1.00 75.30  ? 88  MET B N   1 
ATOM   4438  C CA  . MET B 1 28  ? -39.739  -27.929 43.521  1.00 76.72  ? 88  MET B CA  1 
ATOM   4439  C C   . MET B 1 28  ? -39.993  -26.673 42.703  1.00 66.03  ? 88  MET B C   1 
ATOM   4440  O O   . MET B 1 28  ? -39.092  -25.852 42.599  1.00 64.00  ? 88  MET B O   1 
ATOM   4441  C CB  . MET B 1 28  ? -39.536  -27.548 44.990  1.00 83.19  ? 88  MET B CB  1 
ATOM   4442  C CG  . MET B 1 28  ? -40.797  -27.036 45.663  1.00 93.06  ? 88  MET B CG  1 
ATOM   4443  S SD  . MET B 1 28  ? -41.288  -27.996 47.090  1.00 94.46  ? 88  MET B SD  1 
ATOM   4444  C CE  . MET B 1 28  ? -40.979  -29.655 46.485  1.00 93.48  ? 88  MET B CE  1 
ATOM   4445  N N   . PRO B 1 29  ? -41.188  -26.491 42.095  1.00 56.44  ? 89  PRO B N   1 
ATOM   4446  C CA  . PRO B 1 29  ? -41.467  -25.260 41.353  1.00 48.66  ? 89  PRO B CA  1 
ATOM   4447  C C   . PRO B 1 29  ? -41.841  -24.092 42.272  1.00 43.18  ? 89  PRO B C   1 
ATOM   4448  O O   . PRO B 1 29  ? -42.970  -23.913 42.501  1.00 45.86  ? 89  PRO B O   1 
ATOM   4449  C CB  . PRO B 1 29  ? -42.631  -25.672 40.442  1.00 48.39  ? 89  PRO B CB  1 
ATOM   4450  C CG  . PRO B 1 29  ? -43.343  -26.767 41.232  1.00 50.23  ? 89  PRO B CG  1 
ATOM   4451  C CD  . PRO B 1 29  ? -42.291  -27.471 42.061  1.00 50.15  ? 89  PRO B CD  1 
ATOM   4452  N N   . TRP B 1 30  ? -40.876  -23.329 42.769  1.00 45.59  ? 90  TRP B N   1 
ATOM   4453  C CA  . TRP B 1 30  ? -41.119  -22.151 43.651  1.00 53.18  ? 90  TRP B CA  1 
ATOM   4454  C C   . TRP B 1 30  ? -41.705  -21.017 42.823  1.00 50.29  ? 90  TRP B C   1 
ATOM   4455  O O   . TRP B 1 30  ? -41.282  -20.861 41.705  1.00 52.47  ? 90  TRP B O   1 
ATOM   4456  C CB  . TRP B 1 30  ? -39.832  -21.729 44.394  1.00 61.27  ? 90  TRP B CB  1 
ATOM   4457  C CG  . TRP B 1 30  ? -39.385  -22.781 45.364  1.00 62.06  ? 90  TRP B CG  1 
ATOM   4458  C CD1 . TRP B 1 30  ? -38.370  -23.679 45.209  1.00 59.49  ? 90  TRP B CD1 1 
ATOM   4459  C CD2 . TRP B 1 30  ? -40.040  -23.112 46.598  1.00 53.15  ? 90  TRP B CD2 1 
ATOM   4460  N NE1 . TRP B 1 30  ? -38.331  -24.533 46.274  1.00 61.04  ? 90  TRP B NE1 1 
ATOM   4461  C CE2 . TRP B 1 30  ? -39.336  -24.199 47.148  1.00 57.91  ? 90  TRP B CE2 1 
ATOM   4462  C CE3 . TRP B 1 30  ? -41.125  -22.580 47.296  1.00 47.59  ? 90  TRP B CE3 1 
ATOM   4463  C CZ2 . TRP B 1 30  ? -39.680  -24.758 48.378  1.00 56.54  ? 90  TRP B CZ2 1 
ATOM   4464  C CZ3 . TRP B 1 30  ? -41.477  -23.140 48.497  1.00 48.47  ? 90  TRP B CZ3 1 
ATOM   4465  C CH2 . TRP B 1 30  ? -40.748  -24.202 49.038  1.00 53.40  ? 90  TRP B CH2 1 
ATOM   4466  N N   . ALA B 1 31  ? -42.698  -20.314 43.339  1.00 53.47  ? 91  ALA B N   1 
ATOM   4467  C CA  . ALA B 1 31  ? -43.282  -19.138 42.658  1.00 61.66  ? 91  ALA B CA  1 
ATOM   4468  C C   . ALA B 1 31  ? -43.060  -17.945 43.571  1.00 58.41  ? 91  ALA B C   1 
ATOM   4469  O O   . ALA B 1 31  ? -43.247  -18.101 44.772  1.00 62.47  ? 91  ALA B O   1 
ATOM   4470  C CB  . ALA B 1 31  ? -44.750  -19.348 42.354  1.00 64.47  ? 91  ALA B CB  1 
ATOM   4471  N N   . THR B 1 32  ? -42.651  -16.812 43.015  1.00 63.24  ? 92  THR B N   1 
ATOM   4472  C CA  . THR B 1 32  ? -42.365  -15.576 43.791  1.00 72.18  ? 92  THR B CA  1 
ATOM   4473  C C   . THR B 1 32  ? -43.514  -14.588 43.557  1.00 65.38  ? 92  THR B C   1 
ATOM   4474  O O   . THR B 1 32  ? -43.934  -14.432 42.407  1.00 74.31  ? 92  THR B O   1 
ATOM   4475  C CB  . THR B 1 32  ? -40.979  -15.001 43.456  1.00 81.87  ? 92  THR B CB  1 
ATOM   4476  O OG1 . THR B 1 32  ? -41.066  -13.975 42.463  1.00 88.26  ? 92  THR B OG1 1 
ATOM   4477  C CG2 . THR B 1 32  ? -39.992  -16.051 42.978  1.00 91.15  ? 92  THR B CG2 1 
ATOM   4478  N N   . SER B 1 33  ? -43.997  -13.938 44.607  1.00 55.67  ? 93  SER B N   1 
ATOM   4479  C CA  . SER B 1 33  ? -45.062  -12.916 44.532  1.00 47.63  ? 93  SER B CA  1 
ATOM   4480  C C   . SER B 1 33  ? -44.774  -11.796 45.529  1.00 46.65  ? 93  SER B C   1 
ATOM   4481  O O   . SER B 1 33  ? -44.295  -12.096 46.657  1.00 46.58  ? 93  SER B O   1 
ATOM   4482  C CB  . SER B 1 33  ? -46.375  -13.546 44.825  1.00 52.68  ? 93  SER B CB  1 
ATOM   4483  O OG  . SER B 1 33  ? -46.452  -13.903 46.203  1.00 52.22  ? 93  SER B OG  1 
ATOM   4484  N N   . VAL B 1 34  ? -45.117  -10.564 45.153  1.00 47.62  ? 94  VAL B N   1 
ATOM   4485  C CA  . VAL B 1 34  ? -45.064  -9.369  46.039  1.00 48.08  ? 94  VAL B CA  1 
ATOM   4486  C C   . VAL B 1 34  ? -45.968  -9.670  47.230  1.00 52.77  ? 94  VAL B C   1 
ATOM   4487  O O   . VAL B 1 34  ? -47.127  -10.032 47.007  1.00 59.44  ? 94  VAL B O   1 
ATOM   4488  C CB  . VAL B 1 34  ? -45.543  -8.097  45.322  1.00 47.73  ? 94  VAL B CB  1 
ATOM   4489  C CG1 . VAL B 1 34  ? -45.617  -6.895  46.255  1.00 47.30  ? 94  VAL B CG1 1 
ATOM   4490  C CG2 . VAL B 1 34  ? -44.674  -7.793  44.121  1.00 46.25  ? 94  VAL B CG2 1 
ATOM   4491  N N   . ALA B 1 35  ? -45.454  -9.530  48.448  1.00 54.39  ? 95  ALA B N   1 
ATOM   4492  C CA  . ALA B 1 35  ? -46.236  -9.624  49.698  1.00 51.97  ? 95  ALA B CA  1 
ATOM   4493  C C   . ALA B 1 35  ? -46.895  -8.268  50.009  1.00 56.12  ? 95  ALA B C   1 
ATOM   4494  O O   . ALA B 1 35  ? -46.230  -7.194  49.926  1.00 49.71  ? 95  ALA B O   1 
ATOM   4495  C CB  . ALA B 1 35  ? -45.334  -10.084 50.802  1.00 55.44  ? 95  ALA B CB  1 
ATOM   4496  N N   . SER B 1 36  ? -48.187  -8.329  50.351  1.00 59.98  ? 96  SER B N   1 
ATOM   4497  C CA  . SER B 1 36  ? -48.997  -7.209  50.896  1.00 65.05  ? 96  SER B CA  1 
ATOM   4498  C C   . SER B 1 36  ? -50.105  -7.774  51.812  1.00 61.75  ? 96  SER B C   1 
ATOM   4499  O O   . SER B 1 36  ? -50.189  -9.032  51.963  1.00 60.61  ? 96  SER B O   1 
ATOM   4500  C CB  . SER B 1 36  ? -49.507  -6.351  49.781  1.00 69.53  ? 96  SER B CB  1 
ATOM   4501  O OG  . SER B 1 36  ? -49.848  -7.145  48.656  1.00 83.04  ? 96  SER B OG  1 
ATOM   4502  N N   . GLY B 1 37  ? -50.854  -6.884  52.477  1.00 57.19  ? 97  GLY B N   1 
ATOM   4503  C CA  . GLY B 1 37  ? -51.918  -7.233  53.447  1.00 50.75  ? 97  GLY B CA  1 
ATOM   4504  C C   . GLY B 1 37  ? -51.504  -8.337  54.410  1.00 43.51  ? 97  GLY B C   1 
ATOM   4505  O O   . GLY B 1 37  ? -50.382  -8.309  54.890  1.00 43.53  ? 97  GLY B O   1 
ATOM   4506  N N   . TYR B 1 38  ? -52.369  -9.317  54.660  1.00 44.33  ? 98  TYR B N   1 
ATOM   4507  C CA  . TYR B 1 38  ? -52.153  -10.388 55.675  1.00 47.92  ? 98  TYR B CA  1 
ATOM   4508  C C   . TYR B 1 38  ? -50.996  -11.312 55.281  1.00 47.72  ? 98  TYR B C   1 
ATOM   4509  O O   . TYR B 1 38  ? -50.378  -11.835 56.234  1.00 45.50  ? 98  TYR B O   1 
ATOM   4510  C CB  . TYR B 1 38  ? -53.437  -11.181 55.997  1.00 51.18  ? 98  TYR B CB  1 
ATOM   4511  C CG  . TYR B 1 38  ? -54.297  -10.494 57.030  1.00 53.45  ? 98  TYR B CG  1 
ATOM   4512  C CD1 . TYR B 1 38  ? -53.916  -10.500 58.356  1.00 56.88  ? 98  TYR B CD1 1 
ATOM   4513  C CD2 . TYR B 1 38  ? -55.394  -9.721  56.689  1.00 53.46  ? 98  TYR B CD2 1 
ATOM   4514  C CE1 . TYR B 1 38  ? -54.629  -9.826  59.328  1.00 57.94  ? 98  TYR B CE1 1 
ATOM   4515  C CE2 . TYR B 1 38  ? -56.116  -9.031  57.648  1.00 56.00  ? 98  TYR B CE2 1 
ATOM   4516  C CZ  . TYR B 1 38  ? -55.735  -9.084  58.978  1.00 58.08  ? 98  TYR B CZ  1 
ATOM   4517  O OH  . TYR B 1 38  ? -56.404  -8.426  59.980  1.00 65.59  ? 98  TYR B OH  1 
ATOM   4518  N N   . THR B 1 39  ? -50.674  -11.481 53.987  1.00 46.16  ? 99  THR B N   1 
ATOM   4519  C CA  . THR B 1 39  ? -49.531  -12.329 53.554  1.00 50.42  ? 99  THR B CA  1 
ATOM   4520  C C   . THR B 1 39  ? -48.247  -11.728 54.141  1.00 52.47  ? 99  THR B C   1 
ATOM   4521  O O   . THR B 1 39  ? -47.475  -12.499 54.771  1.00 53.11  ? 99  THR B O   1 
ATOM   4522  C CB  . THR B 1 39  ? -49.391  -12.441 52.032  1.00 57.77  ? 99  THR B CB  1 
ATOM   4523  O OG1 . THR B 1 39  ? -50.665  -12.546 51.407  1.00 68.80  ? 99  THR B OG1 1 
ATOM   4524  C CG2 . THR B 1 39  ? -48.562  -13.635 51.612  1.00 64.17  ? 99  THR B CG2 1 
ATOM   4525  N N   . LEU B 1 40  ? -48.049  -10.405 53.978  1.00 45.78  ? 100 LEU B N   1 
ATOM   4526  C CA  . LEU B 1 40  ? -46.891  -9.642  54.512  1.00 43.09  ? 100 LEU B CA  1 
ATOM   4527  C C   . LEU B 1 40  ? -46.839  -9.740  56.045  1.00 48.47  ? 100 LEU B C   1 
ATOM   4528  O O   . LEU B 1 40  ? -45.748  -10.008 56.564  1.00 46.43  ? 100 LEU B O   1 
ATOM   4529  C CB  . LEU B 1 40  ? -47.006  -8.187  54.046  1.00 44.63  ? 100 LEU B CB  1 
ATOM   4530  C CG  . LEU B 1 40  ? -46.012  -7.180  54.627  1.00 44.85  ? 100 LEU B CG  1 
ATOM   4531  C CD1 . LEU B 1 40  ? -44.588  -7.662  54.433  1.00 50.07  ? 100 LEU B CD1 1 
ATOM   4532  C CD2 . LEU B 1 40  ? -46.213  -5.793  54.017  1.00 43.12  ? 100 LEU B CD2 1 
ATOM   4533  N N   . LEU B 1 41  ? -47.957  -9.507  56.755  1.00 45.77  ? 101 LEU B N   1 
ATOM   4534  C CA  . LEU B 1 41  ? -47.977  -9.465  58.234  1.00 41.68  ? 101 LEU B CA  1 
ATOM   4535  C C   . LEU B 1 41  ? -47.673  -10.852 58.799  1.00 43.64  ? 101 LEU B C   1 
ATOM   4536  O O   . LEU B 1 41  ? -46.958  -10.902 59.805  1.00 42.89  ? 101 LEU B O   1 
ATOM   4537  C CB  . LEU B 1 41  ? -49.340  -8.976  58.704  1.00 46.45  ? 101 LEU B CB  1 
ATOM   4538  C CG  . LEU B 1 41  ? -49.727  -7.567  58.281  1.00 51.63  ? 101 LEU B CG  1 
ATOM   4539  C CD1 . LEU B 1 41  ? -51.137  -7.248  58.725  1.00 53.26  ? 101 LEU B CD1 1 
ATOM   4540  C CD2 . LEU B 1 41  ? -48.783  -6.523  58.838  1.00 57.12  ? 101 LEU B CD2 1 
ATOM   4541  N N   . ARG B 1 42  ? -48.161  -11.923 58.158  1.00 49.36  ? 102 ARG B N   1 
ATOM   4542  C CA  . ARG B 1 42  ? -47.986  -13.338 58.597  1.00 56.43  ? 102 ARG B CA  1 
ATOM   4543  C C   . ARG B 1 42  ? -46.570  -13.855 58.238  1.00 64.61  ? 102 ARG B C   1 
ATOM   4544  O O   . ARG B 1 42  ? -46.227  -14.958 58.766  1.00 57.45  ? 102 ARG B O   1 
ATOM   4545  C CB  . ARG B 1 42  ? -49.041  -14.241 57.934  1.00 58.90  ? 102 ARG B CB  1 
ATOM   4546  C CG  . ARG B 1 42  ? -50.089  -14.921 58.812  1.00 70.54  ? 102 ARG B CG  1 
ATOM   4547  C CD  . ARG B 1 42  ? -51.310  -14.143 59.298  1.00 78.80  ? 102 ARG B CD  1 
ATOM   4548  N NE  . ARG B 1 42  ? -52.520  -14.220 58.458  1.00 82.67  ? 102 ARG B NE  1 
ATOM   4549  C CZ  . ARG B 1 42  ? -53.772  -13.994 58.874  1.00 74.85  ? 102 ARG B CZ  1 
ATOM   4550  N NH1 . ARG B 1 42  ? -54.771  -14.049 58.011  1.00 72.67  ? 102 ARG B NH1 1 
ATOM   4551  N NH2 . ARG B 1 42  ? -54.032  -13.710 60.143  1.00 69.84  ? 102 ARG B NH2 1 
ATOM   4552  N N   . ASP B 1 43  ? -45.799  -13.101 57.422  1.00 57.35  ? 103 ASP B N   1 
ATOM   4553  C CA  . ASP B 1 43  ? -44.396  -13.412 57.032  1.00 54.60  ? 103 ASP B CA  1 
ATOM   4554  C C   . ASP B 1 43  ? -43.404  -12.840 58.048  1.00 50.42  ? 103 ASP B C   1 
ATOM   4555  O O   . ASP B 1 43  ? -43.140  -11.641 58.117  1.00 44.58  ? 103 ASP B O   1 
ATOM   4556  C CB  . ASP B 1 43  ? -44.073  -12.897 55.630  1.00 59.60  ? 103 ASP B CB  1 
ATOM   4557  C CG  . ASP B 1 43  ? -42.688  -13.232 55.105  1.00 64.05  ? 103 ASP B CG  1 
ATOM   4558  O OD1 . ASP B 1 43  ? -42.019  -14.118 55.665  1.00 78.80  ? 103 ASP B OD1 1 
ATOM   4559  O OD2 . ASP B 1 43  ? -42.308  -12.626 54.110  1.00 72.56  ? 103 ASP B OD2 1 
ATOM   4560  N N   . PRO B 1 44  ? -42.760  -13.707 58.844  1.00 53.24  ? 104 PRO B N   1 
ATOM   4561  C CA  . PRO B 1 44  ? -41.812  -13.233 59.837  1.00 53.74  ? 104 PRO B CA  1 
ATOM   4562  C C   . PRO B 1 44  ? -40.673  -12.416 59.211  1.00 57.32  ? 104 PRO B C   1 
ATOM   4563  O O   . PRO B 1 44  ? -40.429  -11.332 59.694  1.00 63.71  ? 104 PRO B O   1 
ATOM   4564  C CB  . PRO B 1 44  ? -41.305  -14.508 60.531  1.00 53.08  ? 104 PRO B CB  1 
ATOM   4565  C CG  . PRO B 1 44  ? -41.845  -15.716 59.737  1.00 47.62  ? 104 PRO B CG  1 
ATOM   4566  C CD  . PRO B 1 44  ? -42.890  -15.176 58.799  1.00 52.55  ? 104 PRO B CD  1 
ATOM   4567  N N   . HIS B 1 45  ? -40.024  -12.955 58.170  1.00 56.93  ? 105 HIS B N   1 
ATOM   4568  C CA  . HIS B 1 45  ? -38.854  -12.343 57.484  1.00 56.19  ? 105 HIS B CA  1 
ATOM   4569  C C   . HIS B 1 45  ? -39.110  -10.843 57.214  1.00 53.30  ? 105 HIS B C   1 
ATOM   4570  O O   . HIS B 1 45  ? -38.183  -10.034 57.418  1.00 55.01  ? 105 HIS B O   1 
ATOM   4571  C CB  . HIS B 1 45  ? -38.497  -13.151 56.231  1.00 61.26  ? 105 HIS B CB  1 
ATOM   4572  C CG  . HIS B 1 45  ? -37.186  -12.833 55.585  1.00 70.31  ? 105 HIS B CG  1 
ATOM   4573  N ND1 . HIS B 1 45  ? -36.405  -11.712 55.877  1.00 79.44  ? 105 HIS B ND1 1 
ATOM   4574  C CD2 . HIS B 1 45  ? -36.502  -13.515 54.634  1.00 76.36  ? 105 HIS B CD2 1 
ATOM   4575  C CE1 . HIS B 1 45  ? -35.319  -11.710 55.128  1.00 78.10  ? 105 HIS B CE1 1 
ATOM   4576  N NE2 . HIS B 1 45  ? -35.349  -12.812 54.356  1.00 80.74  ? 105 HIS B NE2 1 
ATOM   4577  N N   . HIS B 1 46  ? -40.313  -10.450 56.791  1.00 51.93  ? 106 HIS B N   1 
ATOM   4578  C CA  . HIS B 1 46  ? -40.620  -9.044  56.404  1.00 60.46  ? 106 HIS B CA  1 
ATOM   4579  C C   . HIS B 1 46  ? -41.452  -8.309  57.472  1.00 62.10  ? 106 HIS B C   1 
ATOM   4580  O O   . HIS B 1 46  ? -41.370  -7.064  57.536  1.00 61.06  ? 106 HIS B O   1 
ATOM   4581  C CB  . HIS B 1 46  ? -41.307  -9.026  55.034  1.00 62.86  ? 106 HIS B CB  1 
ATOM   4582  C CG  . HIS B 1 46  ? -40.435  -9.559  53.946  1.00 66.13  ? 106 HIS B CG  1 
ATOM   4583  N ND1 . HIS B 1 46  ? -39.186  -9.021  53.674  1.00 66.91  ? 106 HIS B ND1 1 
ATOM   4584  C CD2 . HIS B 1 46  ? -40.607  -10.581 53.075  1.00 68.02  ? 106 HIS B CD2 1 
ATOM   4585  C CE1 . HIS B 1 46  ? -38.620  -9.711  52.698  1.00 72.82  ? 106 HIS B CE1 1 
ATOM   4586  N NE2 . HIS B 1 46  ? -39.481  -10.669 52.303  1.00 66.18  ? 106 HIS B NE2 1 
ATOM   4587  N N   . ASN B 1 47  ? -42.254  -9.016  58.264  1.00 51.83  ? 107 ASN B N   1 
ATOM   4588  C CA  . ASN B 1 47  ? -43.309  -8.347  59.060  1.00 51.14  ? 107 ASN B CA  1 
ATOM   4589  C C   . ASN B 1 47  ? -42.670  -7.348  60.033  1.00 51.18  ? 107 ASN B C   1 
ATOM   4590  O O   . ASN B 1 47  ? -41.903  -7.783  60.918  1.00 46.26  ? 107 ASN B O   1 
ATOM   4591  C CB  . ASN B 1 47  ? -44.174  -9.332  59.847  1.00 56.20  ? 107 ASN B CB  1 
ATOM   4592  C CG  . ASN B 1 47  ? -44.941  -8.625  60.946  1.00 47.91  ? 107 ASN B CG  1 
ATOM   4593  O OD1 . ASN B 1 47  ? -45.721  -7.723  60.668  1.00 39.93  ? 107 ASN B OD1 1 
ATOM   4594  N ND2 . ASN B 1 47  ? -44.637  -8.958  62.187  1.00 43.31  ? 107 ASN B ND2 1 
ATOM   4595  N N   . LYS B 1 48  ? -43.055  -6.076  59.930  1.00 49.64  ? 108 LYS B N   1 
ATOM   4596  C CA  . LYS B 1 48  ? -42.584  -5.008  60.846  1.00 56.01  ? 108 LYS B CA  1 
ATOM   4597  C C   . LYS B 1 48  ? -43.651  -4.647  61.891  1.00 55.95  ? 108 LYS B C   1 
ATOM   4598  O O   . LYS B 1 48  ? -43.376  -3.708  62.659  1.00 69.50  ? 108 LYS B O   1 
ATOM   4599  C CB  . LYS B 1 48  ? -42.184  -3.755  60.056  1.00 58.73  ? 108 LYS B CB  1 
ATOM   4600  C CG  . LYS B 1 48  ? -41.086  -3.974  59.008  1.00 59.40  ? 108 LYS B CG  1 
ATOM   4601  C CD  . LYS B 1 48  ? -40.731  -2.744  58.163  1.00 55.29  ? 108 LYS B CD  1 
ATOM   4602  C CE  . LYS B 1 48  ? -40.506  -1.503  59.010  1.00 63.52  ? 108 LYS B CE  1 
ATOM   4603  N NZ  . LYS B 1 48  ? -40.138  -0.310  58.207  1.00 64.77  ? 108 LYS B NZ  1 
ATOM   4604  N N   . GLY B 1 49  ? -44.808  -5.319  61.945  1.00 46.63  ? 109 GLY B N   1 
ATOM   4605  C CA  . GLY B 1 49  ? -45.919  -4.883  62.829  1.00 47.87  ? 109 GLY B CA  1 
ATOM   4606  C C   . GLY B 1 49  ? -46.095  -3.364  62.806  1.00 44.37  ? 109 GLY B C   1 
ATOM   4607  O O   . GLY B 1 49  ? -45.896  -2.792  61.744  1.00 45.88  ? 109 GLY B O   1 
ATOM   4608  N N   . LEU B 1 50  ? -46.361  -2.700  63.934  1.00 46.38  ? 110 LEU B N   1 
ATOM   4609  C CA  . LEU B 1 50  ? -46.704  -1.244  63.971  1.00 51.22  ? 110 LEU B CA  1 
ATOM   4610  C C   . LEU B 1 50  ? -45.558  -0.363  63.478  1.00 52.69  ? 110 LEU B C   1 
ATOM   4611  O O   . LEU B 1 50  ? -45.788  0.864   63.419  1.00 54.53  ? 110 LEU B O   1 
ATOM   4612  C CB  . LEU B 1 50  ? -47.073  -0.798  65.386  1.00 55.46  ? 110 LEU B CB  1 
ATOM   4613  C CG  . LEU B 1 50  ? -48.283  -1.500  65.990  1.00 63.71  ? 110 LEU B CG  1 
ATOM   4614  C CD1 . LEU B 1 50  ? -48.553  -1.010  67.395  1.00 69.69  ? 110 LEU B CD1 1 
ATOM   4615  C CD2 . LEU B 1 50  ? -49.516  -1.287  65.128  1.00 69.03  ? 110 LEU B CD2 1 
ATOM   4616  N N   . ALA B 1 51  ? -44.387  -0.933  63.183  1.00 54.60  ? 111 ALA B N   1 
ATOM   4617  C CA  . ALA B 1 51  ? -43.188  -0.179  62.754  1.00 56.79  ? 111 ALA B CA  1 
ATOM   4618  C C   . ALA B 1 51  ? -43.278  0.097   61.255  1.00 56.22  ? 111 ALA B C   1 
ATOM   4619  O O   . ALA B 1 51  ? -42.529  0.991   60.789  1.00 48.80  ? 111 ALA B O   1 
ATOM   4620  C CB  . ALA B 1 51  ? -41.913  -0.900  63.110  1.00 56.10  ? 111 ALA B CB  1 
ATOM   4621  N N   . PHE B 1 52  ? -44.181  -0.592  60.541  1.00 50.60  ? 112 PHE B N   1 
ATOM   4622  C CA  . PHE B 1 52  ? -44.599  -0.203  59.162  1.00 48.22  ? 112 PHE B CA  1 
ATOM   4623  C C   . PHE B 1 52  ? -45.017  1.272   59.141  1.00 51.90  ? 112 PHE B C   1 
ATOM   4624  O O   . PHE B 1 52  ? -45.988  1.630   59.797  1.00 61.71  ? 112 PHE B O   1 
ATOM   4625  C CB  . PHE B 1 52  ? -45.764  -1.045  58.649  1.00 44.09  ? 112 PHE B CB  1 
ATOM   4626  C CG  . PHE B 1 52  ? -45.334  -2.360  58.075  1.00 44.88  ? 112 PHE B CG  1 
ATOM   4627  C CD1 . PHE B 1 52  ? -44.491  -2.375  56.983  1.00 44.96  ? 112 PHE B CD1 1 
ATOM   4628  C CD2 . PHE B 1 52  ? -45.766  -3.566  58.621  1.00 48.52  ? 112 PHE B CD2 1 
ATOM   4629  C CE1 . PHE B 1 52  ? -44.094  -3.585  56.441  1.00 54.14  ? 112 PHE B CE1 1 
ATOM   4630  C CE2 . PHE B 1 52  ? -45.364  -4.774  58.078  1.00 51.39  ? 112 PHE B CE2 1 
ATOM   4631  C CZ  . PHE B 1 52  ? -44.532  -4.782  56.986  1.00 54.35  ? 112 PHE B CZ  1 
ATOM   4632  N N   . THR B 1 53  ? -44.293  2.112   58.412  1.00 54.40  ? 113 THR B N   1 
ATOM   4633  C CA  . THR B 1 53  ? -44.590  3.557   58.271  1.00 57.19  ? 113 THR B CA  1 
ATOM   4634  C C   . THR B 1 53  ? -45.931  3.716   57.542  1.00 62.57  ? 113 THR B C   1 
ATOM   4635  O O   . THR B 1 53  ? -46.347  2.782   56.833  1.00 52.66  ? 113 THR B O   1 
ATOM   4636  C CB  . THR B 1 53  ? -43.445  4.271   57.548  1.00 60.24  ? 113 THR B CB  1 
ATOM   4637  O OG1 . THR B 1 53  ? -43.315  3.731   56.232  1.00 54.59  ? 113 THR B OG1 1 
ATOM   4638  C CG2 . THR B 1 53  ? -42.124  4.140   58.268  1.00 62.59  ? 113 THR B CG2 1 
ATOM   4639  N N   . GLU B 1 54  ? -46.587  4.860   57.725  1.00 74.52  ? 114 GLU B N   1 
ATOM   4640  C CA  . GLU B 1 54  ? -47.850  5.260   57.043  1.00 71.69  ? 114 GLU B CA  1 
ATOM   4641  C C   . GLU B 1 54  ? -47.732  4.909   55.553  1.00 66.55  ? 114 GLU B C   1 
ATOM   4642  O O   . GLU B 1 54  ? -48.625  4.201   55.042  1.00 50.01  ? 114 GLU B O   1 
ATOM   4643  C CB  . GLU B 1 54  ? -48.064  6.759   57.326  1.00 70.93  ? 114 GLU B CB  1 
ATOM   4644  C CG  . GLU B 1 54  ? -49.193  7.436   56.577  1.00 74.52  ? 114 GLU B CG  1 
ATOM   4645  C CD  . GLU B 1 54  ? -49.970  8.446   57.413  1.00 81.89  ? 114 GLU B CD  1 
ATOM   4646  O OE1 . GLU B 1 54  ? -50.721  9.297   56.849  1.00 91.39  ? 114 GLU B OE1 1 
ATOM   4647  O OE2 . GLU B 1 54  ? -49.860  8.345   58.638  1.00 74.43  ? 114 GLU B OE2 1 
ATOM   4648  N N   . GLU B 1 55  ? -46.629  5.353   54.920  1.00 66.85  ? 115 GLU B N   1 
ATOM   4649  C CA  . GLU B 1 55  ? -46.343  5.244   53.461  1.00 63.67  ? 115 GLU B CA  1 
ATOM   4650  C C   . GLU B 1 55  ? -46.297  3.758   53.082  1.00 61.41  ? 115 GLU B C   1 
ATOM   4651  O O   . GLU B 1 55  ? -46.851  3.394   52.047  1.00 58.18  ? 115 GLU B O   1 
ATOM   4652  C CB  . GLU B 1 55  ? -45.041  5.978   53.126  1.00 71.01  ? 115 GLU B CB  1 
ATOM   4653  C CG  . GLU B 1 55  ? -45.016  7.443   53.582  1.00 81.88  ? 115 GLU B CG  1 
ATOM   4654  C CD  . GLU B 1 55  ? -44.334  7.864   54.891  1.00 83.91  ? 115 GLU B CD  1 
ATOM   4655  O OE1 . GLU B 1 55  ? -43.777  7.051   55.680  1.00 74.38  ? 115 GLU B OE1 1 
ATOM   4656  O OE2 . GLU B 1 55  ? -44.281  9.080   55.094  1.00 84.09  ? 115 GLU B OE2 1 
ATOM   4657  N N   . GLU B 1 56  ? -45.676  2.923   53.917  1.00 60.53  ? 116 GLU B N   1 
ATOM   4658  C CA  . GLU B 1 56  ? -45.535  1.459   53.680  1.00 56.62  ? 116 GLU B CA  1 
ATOM   4659  C C   . GLU B 1 56  ? -46.895  0.760   53.755  1.00 60.41  ? 116 GLU B C   1 
ATOM   4660  O O   . GLU B 1 56  ? -47.067  -0.224  53.020  1.00 59.31  ? 116 GLU B O   1 
ATOM   4661  C CB  . GLU B 1 56  ? -44.608  0.826   54.718  1.00 61.84  ? 116 GLU B CB  1 
ATOM   4662  C CG  . GLU B 1 56  ? -43.154  1.214   54.533  1.00 68.14  ? 116 GLU B CG  1 
ATOM   4663  C CD  . GLU B 1 56  ? -42.166  0.769   55.596  1.00 56.65  ? 116 GLU B CD  1 
ATOM   4664  O OE1 . GLU B 1 56  ? -42.574  0.621   56.729  1.00 61.90  ? 116 GLU B OE1 1 
ATOM   4665  O OE2 . GLU B 1 56  ? -40.979  0.629   55.279  1.00 55.21  ? 116 GLU B OE2 1 
ATOM   4666  N N   . ARG B 1 57  ? -47.791  1.226   54.640  1.00 54.15  ? 117 ARG B N   1 
ATOM   4667  C CA  . ARG B 1 57  ? -49.147  0.656   54.865  1.00 52.26  ? 117 ARG B CA  1 
ATOM   4668  C C   . ARG B 1 57  ? -50.050  0.936   53.651  1.00 61.24  ? 117 ARG B C   1 
ATOM   4669  O O   . ARG B 1 57  ? -50.704  -0.031  53.168  1.00 72.04  ? 117 ARG B O   1 
ATOM   4670  C CB  . ARG B 1 57  ? -49.771  1.244   56.130  1.00 50.66  ? 117 ARG B CB  1 
ATOM   4671  C CG  . ARG B 1 57  ? -48.950  1.063   57.393  1.00 52.83  ? 117 ARG B CG  1 
ATOM   4672  C CD  . ARG B 1 57  ? -49.697  1.345   58.696  1.00 46.13  ? 117 ARG B CD  1 
ATOM   4673  N NE  . ARG B 1 57  ? -48.816  1.198   59.850  1.00 45.21  ? 117 ARG B NE  1 
ATOM   4674  C CZ  . ARG B 1 57  ? -49.166  1.431   61.096  1.00 49.32  ? 117 ARG B CZ  1 
ATOM   4675  N NH1 . ARG B 1 57  ? -50.403  1.795   61.350  1.00 48.93  ? 117 ARG B NH1 1 
ATOM   4676  N NH2 . ARG B 1 57  ? -48.292  1.307   62.085  1.00 54.29  ? 117 ARG B NH2 1 
ATOM   4677  N N   . ASP B 1 58  ? -50.109  2.195   53.182  1.00 62.66  ? 118 ASP B N   1 
ATOM   4678  C CA  . ASP B 1 58  ? -50.822  2.580   51.928  1.00 64.40  ? 118 ASP B CA  1 
ATOM   4679  C C   . ASP B 1 58  ? -50.304  1.701   50.793  1.00 56.01  ? 118 ASP B C   1 
ATOM   4680  O O   . ASP B 1 58  ? -51.112  1.070   50.090  1.00 67.31  ? 118 ASP B O   1 
ATOM   4681  C CB  . ASP B 1 58  ? -50.648  4.066   51.595  1.00 69.19  ? 118 ASP B CB  1 
ATOM   4682  C CG  . ASP B 1 58  ? -51.271  4.990   52.631  1.00 82.74  ? 118 ASP B CG  1 
ATOM   4683  O OD1 . ASP B 1 58  ? -51.926  4.474   53.553  1.00 94.69  ? 118 ASP B OD1 1 
ATOM   4684  O OD2 . ASP B 1 58  ? -51.058  6.215   52.527  1.00 84.65  ? 118 ASP B OD2 1 
ATOM   4685  N N   . GLY B 1 59  ? -48.990  1.632   50.684  1.00 54.65  ? 119 GLY B N   1 
ATOM   4686  C CA  . GLY B 1 59  ? -48.270  0.881   49.649  1.00 60.25  ? 119 GLY B CA  1 
ATOM   4687  C C   . GLY B 1 59  ? -48.622  -0.595  49.644  1.00 62.51  ? 119 GLY B C   1 
ATOM   4688  O O   . GLY B 1 59  ? -48.649  -1.141  48.541  1.00 71.60  ? 119 GLY B O   1 
ATOM   4689  N N   . HIS B 1 60  ? -48.864  -1.234  50.794  1.00 53.18  ? 120 HIS B N   1 
ATOM   4690  C CA  . HIS B 1 60  ? -48.957  -2.715  50.856  1.00 58.96  ? 120 HIS B CA  1 
ATOM   4691  C C   . HIS B 1 60  ? -50.288  -3.181  51.433  1.00 57.71  ? 120 HIS B C   1 
ATOM   4692  O O   . HIS B 1 60  ? -50.330  -4.347  51.913  1.00 51.32  ? 120 HIS B O   1 
ATOM   4693  C CB  . HIS B 1 60  ? -47.792  -3.324  51.635  1.00 64.64  ? 120 HIS B CB  1 
ATOM   4694  C CG  . HIS B 1 60  ? -46.486  -3.167  50.943  1.00 67.07  ? 120 HIS B CG  1 
ATOM   4695  N ND1 . HIS B 1 60  ? -46.084  -3.998  49.910  1.00 65.84  ? 120 HIS B ND1 1 
ATOM   4696  C CD2 . HIS B 1 60  ? -45.494  -2.277  51.138  1.00 70.19  ? 120 HIS B CD2 1 
ATOM   4697  C CE1 . HIS B 1 60  ? -44.887  -3.615  49.510  1.00 73.78  ? 120 HIS B CE1 1 
ATOM   4698  N NE2 . HIS B 1 60  ? -44.497  -2.565  50.248  1.00 66.25  ? 120 HIS B NE2 1 
ATOM   4699  N N   . TYR B 1 61  ? -51.318  -2.338  51.370  1.00 51.07  ? 121 TYR B N   1 
ATOM   4700  C CA  . TYR B 1 61  ? -52.697  -2.742  51.735  1.00 58.96  ? 121 TYR B CA  1 
ATOM   4701  C C   . TYR B 1 61  ? -52.723  -3.231  53.182  1.00 55.20  ? 121 TYR B C   1 
ATOM   4702  O O   . TYR B 1 61  ? -53.296  -4.292  53.477  1.00 54.66  ? 121 TYR B O   1 
ATOM   4703  C CB  . TYR B 1 61  ? -53.200  -3.787  50.735  1.00 66.28  ? 121 TYR B CB  1 
ATOM   4704  C CG  . TYR B 1 61  ? -53.014  -3.337  49.308  1.00 72.60  ? 121 TYR B CG  1 
ATOM   4705  C CD1 . TYR B 1 61  ? -53.642  -2.182  48.845  1.00 77.60  ? 121 TYR B CD1 1 
ATOM   4706  C CD2 . TYR B 1 61  ? -52.178  -4.020  48.441  1.00 73.82  ? 121 TYR B CD2 1 
ATOM   4707  C CE1 . TYR B 1 61  ? -53.466  -1.725  47.556  1.00 72.53  ? 121 TYR B CE1 1 
ATOM   4708  C CE2 . TYR B 1 61  ? -51.969  -3.566  47.150  1.00 79.40  ? 121 TYR B CE2 1 
ATOM   4709  C CZ  . TYR B 1 61  ? -52.625  -2.425  46.705  1.00 84.09  ? 121 TYR B CZ  1 
ATOM   4710  O OH  . TYR B 1 61  ? -52.438  -1.991  45.424  1.00 93.94  ? 121 TYR B OH  1 
ATOM   4711  N N   . LEU B 1 62  ? -52.099  -2.448  54.053  1.00 56.06  ? 122 LEU B N   1 
ATOM   4712  C CA  . LEU B 1 62  ? -52.144  -2.634  55.515  1.00 57.27  ? 122 LEU B CA  1 
ATOM   4713  C C   . LEU B 1 62  ? -53.120  -1.626  56.117  1.00 63.22  ? 122 LEU B C   1 
ATOM   4714  O O   . LEU B 1 62  ? -53.664  -1.952  57.186  1.00 70.83  ? 122 LEU B O   1 
ATOM   4715  C CB  . LEU B 1 62  ? -50.745  -2.419  56.090  1.00 60.52  ? 122 LEU B CB  1 
ATOM   4716  C CG  . LEU B 1 62  ? -49.662  -3.321  55.517  1.00 61.40  ? 122 LEU B CG  1 
ATOM   4717  C CD1 . LEU B 1 62  ? -48.350  -3.068  56.222  1.00 61.62  ? 122 LEU B CD1 1 
ATOM   4718  C CD2 . LEU B 1 62  ? -50.066  -4.796  55.581  1.00 60.90  ? 122 LEU B CD2 1 
ATOM   4719  N N   . ARG B 1 63  ? -53.325  -0.452  55.490  1.00 56.00  ? 123 ARG B N   1 
ATOM   4720  C CA  . ARG B 1 63  ? -54.144  0.627   56.109  1.00 54.21  ? 123 ARG B CA  1 
ATOM   4721  C C   . ARG B 1 63  ? -55.438  -0.034  56.607  1.00 53.53  ? 123 ARG B C   1 
ATOM   4722  O O   . ARG B 1 63  ? -56.081  -0.753  55.812  1.00 58.39  ? 123 ARG B O   1 
ATOM   4723  C CB  . ARG B 1 63  ? -54.391  1.760   55.124  1.00 56.99  ? 123 ARG B CB  1 
ATOM   4724  C CG  . ARG B 1 63  ? -55.039  2.984   55.746  1.00 61.65  ? 123 ARG B CG  1 
ATOM   4725  C CD  . ARG B 1 63  ? -55.659  3.821   54.635  1.00 73.77  ? 123 ARG B CD  1 
ATOM   4726  N NE  . ARG B 1 63  ? -54.905  5.008   54.215  1.00 87.62  ? 123 ARG B NE  1 
ATOM   4727  C CZ  . ARG B 1 63  ? -55.022  6.228   54.752  1.00 94.25  ? 123 ARG B CZ  1 
ATOM   4728  N NH1 . ARG B 1 63  ? -55.808  6.434   55.791  1.00 100.00 ? 123 ARG B NH1 1 
ATOM   4729  N NH2 . ARG B 1 63  ? -54.305  7.229   54.281  1.00 108.14 ? 123 ARG B NH2 1 
ATOM   4730  N N   . GLY B 1 64  ? -55.749  0.100   57.893  1.00 47.21  ? 124 GLY B N   1 
ATOM   4731  C CA  . GLY B 1 64  ? -56.932  -0.518  58.503  1.00 45.40  ? 124 GLY B CA  1 
ATOM   4732  C C   . GLY B 1 64  ? -56.593  -1.769  59.281  1.00 48.30  ? 124 GLY B C   1 
ATOM   4733  O O   . GLY B 1 64  ? -57.157  -1.943  60.378  1.00 53.42  ? 124 GLY B O   1 
ATOM   4734  N N   . LEU B 1 65  ? -55.741  -2.639  58.737  1.00 49.60  ? 125 LEU B N   1 
ATOM   4735  C CA  . LEU B 1 65  ? -55.360  -3.929  59.384  1.00 50.07  ? 125 LEU B CA  1 
ATOM   4736  C C   . LEU B 1 65  ? -54.454  -3.640  60.587  1.00 50.27  ? 125 LEU B C   1 
ATOM   4737  O O   . LEU B 1 65  ? -54.341  -4.520  61.441  1.00 55.49  ? 125 LEU B O   1 
ATOM   4738  C CB  . LEU B 1 65  ? -54.610  -4.818  58.388  1.00 52.75  ? 125 LEU B CB  1 
ATOM   4739  C CG  . LEU B 1 65  ? -55.324  -5.183  57.088  1.00 52.01  ? 125 LEU B CG  1 
ATOM   4740  C CD1 . LEU B 1 65  ? -54.447  -6.074  56.220  1.00 52.98  ? 125 LEU B CD1 1 
ATOM   4741  C CD2 . LEU B 1 65  ? -56.661  -5.828  57.367  1.00 52.51  ? 125 LEU B CD2 1 
ATOM   4742  N N   . LEU B 1 66  ? -53.784  -2.477  60.607  1.00 49.03  ? 126 LEU B N   1 
ATOM   4743  C CA  . LEU B 1 66  ? -53.038  -1.971  61.791  1.00 51.01  ? 126 LEU B CA  1 
ATOM   4744  C C   . LEU B 1 66  ? -53.753  -0.750  62.346  1.00 50.37  ? 126 LEU B C   1 
ATOM   4745  O O   . LEU B 1 66  ? -54.362  0.032   61.614  1.00 57.02  ? 126 LEU B O   1 
ATOM   4746  C CB  . LEU B 1 66  ? -51.608  -1.594  61.417  1.00 46.84  ? 126 LEU B CB  1 
ATOM   4747  C CG  . LEU B 1 66  ? -50.783  -2.703  60.774  1.00 53.77  ? 126 LEU B CG  1 
ATOM   4748  C CD1 . LEU B 1 66  ? -49.391  -2.158  60.431  1.00 50.89  ? 126 LEU B CD1 1 
ATOM   4749  C CD2 . LEU B 1 66  ? -50.712  -3.943  61.678  1.00 48.71  ? 126 LEU B CD2 1 
ATOM   4750  N N   . PRO B 1 67  ? -53.673  -0.538  63.666  1.00 41.96  ? 127 PRO B N   1 
ATOM   4751  C CA  . PRO B 1 67  ? -54.148  0.710   64.252  1.00 45.32  ? 127 PRO B CA  1 
ATOM   4752  C C   . PRO B 1 67  ? -53.378  1.902   63.690  1.00 45.18  ? 127 PRO B C   1 
ATOM   4753  O O   . PRO B 1 67  ? -52.326  1.713   63.116  1.00 45.45  ? 127 PRO B O   1 
ATOM   4754  C CB  . PRO B 1 67  ? -53.877  0.554   65.739  1.00 47.27  ? 127 PRO B CB  1 
ATOM   4755  C CG  . PRO B 1 67  ? -53.040  -0.711  65.912  1.00 44.59  ? 127 PRO B CG  1 
ATOM   4756  C CD  . PRO B 1 67  ? -53.120  -1.486  64.627  1.00 42.37  ? 127 PRO B CD  1 
ATOM   4757  N N   . PRO B 1 68  ? -53.859  3.154   63.824  1.00 51.28  ? 128 PRO B N   1 
ATOM   4758  C CA  . PRO B 1 68  ? -53.200  4.311   63.190  1.00 52.49  ? 128 PRO B CA  1 
ATOM   4759  C C   . PRO B 1 68  ? -51.735  4.593   63.580  1.00 56.95  ? 128 PRO B C   1 
ATOM   4760  O O   . PRO B 1 68  ? -50.996  5.064   62.740  1.00 55.91  ? 128 PRO B O   1 
ATOM   4761  C CB  . PRO B 1 68  ? -54.018  5.520   63.663  1.00 55.97  ? 128 PRO B CB  1 
ATOM   4762  C CG  . PRO B 1 68  ? -55.343  4.943   64.148  1.00 55.20  ? 128 PRO B CG  1 
ATOM   4763  C CD  . PRO B 1 68  ? -55.085  3.503   64.549  1.00 50.83  ? 128 PRO B CD  1 
ATOM   4764  N N   . ALA B 1 69  ? -51.341  4.274   64.819  1.00 61.63  ? 129 ALA B N   1 
ATOM   4765  C CA  . ALA B 1 69  ? -50.025  4.613   65.430  1.00 54.02  ? 129 ALA B CA  1 
ATOM   4766  C C   . ALA B 1 69  ? -48.898  3.854   64.733  1.00 55.97  ? 129 ALA B C   1 
ATOM   4767  O O   . ALA B 1 69  ? -48.983  2.579   64.621  1.00 51.99  ? 129 ALA B O   1 
ATOM   4768  C CB  . ALA B 1 69  ? -50.000  4.301   66.912  1.00 49.26  ? 129 ALA B CB  1 
ATOM   4769  N N   . VAL B 1 70  ? -47.847  4.602   64.369  1.00 53.11  ? 130 VAL B N   1 
ATOM   4770  C CA  . VAL B 1 70  ? -46.552  4.048   63.881  1.00 50.00  ? 130 VAL B CA  1 
ATOM   4771  C C   . VAL B 1 70  ? -45.502  4.120   64.997  1.00 53.03  ? 130 VAL B C   1 
ATOM   4772  O O   . VAL B 1 70  ? -45.134  5.229   65.424  1.00 58.72  ? 130 VAL B O   1 
ATOM   4773  C CB  . VAL B 1 70  ? -46.094  4.776   62.611  1.00 52.42  ? 130 VAL B CB  1 
ATOM   4774  C CG1 . VAL B 1 70  ? -44.781  4.201   62.098  1.00 55.01  ? 130 VAL B CG1 1 
ATOM   4775  C CG2 . VAL B 1 70  ? -47.180  4.744   61.531  1.00 52.36  ? 130 VAL B CG2 1 
ATOM   4776  N N   . LEU B 1 71  ? -45.032  2.953   65.433  1.00 56.86  ? 131 LEU B N   1 
ATOM   4777  C CA  . LEU B 1 71  ? -43.914  2.781   66.394  1.00 56.94  ? 131 LEU B CA  1 
ATOM   4778  C C   . LEU B 1 71  ? -42.581  2.699   65.647  1.00 63.03  ? 131 LEU B C   1 
ATOM   4779  O O   . LEU B 1 71  ? -42.553  2.152   64.541  1.00 65.23  ? 131 LEU B O   1 
ATOM   4780  C CB  . LEU B 1 71  ? -44.114  1.471   67.160  1.00 58.57  ? 131 LEU B CB  1 
ATOM   4781  C CG  . LEU B 1 71  ? -45.148  1.504   68.267  1.00 54.08  ? 131 LEU B CG  1 
ATOM   4782  C CD1 . LEU B 1 71  ? -45.082  0.189   69.021  1.00 52.14  ? 131 LEU B CD1 1 
ATOM   4783  C CD2 . LEU B 1 71  ? -44.906  2.704   69.177  1.00 53.34  ? 131 LEU B CD2 1 
ATOM   4784  N N   . SER B 1 72  ? -41.510  3.184   66.277  1.00 64.34  ? 132 SER B N   1 
ATOM   4785  C CA  . SER B 1 72  ? -40.108  2.820   65.970  1.00 62.60  ? 132 SER B CA  1 
ATOM   4786  C C   . SER B 1 72  ? -39.792  1.370   66.408  1.00 73.53  ? 132 SER B C   1 
ATOM   4787  O O   . SER B 1 72  ? -40.559  0.767   67.234  1.00 67.60  ? 132 SER B O   1 
ATOM   4788  C CB  . SER B 1 72  ? -39.193  3.770   66.654  1.00 58.62  ? 132 SER B CB  1 
ATOM   4789  O OG  . SER B 1 72  ? -39.166  3.522   68.050  1.00 51.88  ? 132 SER B OG  1 
ATOM   4790  N N   . GLN B 1 73  ? -38.675  0.832   65.903  1.00 63.17  ? 133 GLN B N   1 
ATOM   4791  C CA  . GLN B 1 73  ? -38.164  -0.494  66.316  1.00 61.44  ? 133 GLN B CA  1 
ATOM   4792  C C   . GLN B 1 73  ? -37.779  -0.402  67.801  1.00 63.23  ? 133 GLN B C   1 
ATOM   4793  O O   . GLN B 1 73  ? -37.921  -1.399  68.495  1.00 65.55  ? 133 GLN B O   1 
ATOM   4794  C CB  . GLN B 1 73  ? -37.012  -0.921  65.398  1.00 63.82  ? 133 GLN B CB  1 
ATOM   4795  C CG  . GLN B 1 73  ? -36.667  -2.401  65.499  1.00 67.41  ? 133 GLN B CG  1 
ATOM   4796  C CD  . GLN B 1 73  ? -35.599  -2.841  64.521  1.00 66.21  ? 133 GLN B CD  1 
ATOM   4797  O OE1 . GLN B 1 73  ? -34.947  -2.009  63.899  1.00 70.85  ? 133 GLN B OE1 1 
ATOM   4798  N NE2 . GLN B 1 73  ? -35.407  -4.155  64.388  1.00 51.20  ? 133 GLN B NE2 1 
ATOM   4799  N N   . GLU B 1 74  ? -37.308  0.762   68.264  1.00 71.68  ? 134 GLU B N   1 
ATOM   4800  C CA  . GLU B 1 74  ? -36.740  0.978   69.631  1.00 77.80  ? 134 GLU B CA  1 
ATOM   4801  C C   . GLU B 1 74  ? -37.865  0.913   70.659  1.00 69.60  ? 134 GLU B C   1 
ATOM   4802  O O   . GLU B 1 74  ? -37.698  0.237   71.706  1.00 58.89  ? 134 GLU B O   1 
ATOM   4803  C CB  . GLU B 1 74  ? -36.024  2.327   69.742  1.00 93.56  ? 134 GLU B CB  1 
ATOM   4804  C CG  . GLU B 1 74  ? -34.730  2.399   68.934  1.00 110.58 ? 134 GLU B CG  1 
ATOM   4805  C CD  . GLU B 1 74  ? -34.910  2.799   67.470  1.00 133.31 ? 134 GLU B CD  1 
ATOM   4806  O OE1 . GLU B 1 74  ? -34.561  1.967   66.580  1.00 127.91 ? 134 GLU B OE1 1 
ATOM   4807  O OE2 . GLU B 1 74  ? -35.390  3.947   67.214  1.00 136.16 ? 134 GLU B OE2 1 
ATOM   4808  N N   . LEU B 1 75  ? -38.962  1.614   70.368  1.00 61.78  ? 135 LEU B N   1 
ATOM   4809  C CA  . LEU B 1 75  ? -40.196  1.550   71.176  1.00 54.78  ? 135 LEU B CA  1 
ATOM   4810  C C   . LEU B 1 75  ? -40.688  0.105   71.190  1.00 49.37  ? 135 LEU B C   1 
ATOM   4811  O O   . LEU B 1 75  ? -41.083  -0.359  72.249  1.00 45.31  ? 135 LEU B O   1 
ATOM   4812  C CB  . LEU B 1 75  ? -41.226  2.501   70.579  1.00 61.95  ? 135 LEU B CB  1 
ATOM   4813  C CG  . LEU B 1 75  ? -41.020  3.958   70.971  1.00 65.97  ? 135 LEU B CG  1 
ATOM   4814  C CD1 . LEU B 1 75  ? -41.984  4.898   70.233  1.00 65.19  ? 135 LEU B CD1 1 
ATOM   4815  C CD2 . LEU B 1 75  ? -41.173  4.100   72.478  1.00 70.50  ? 135 LEU B CD2 1 
ATOM   4816  N N   . GLN B 1 76  ? -40.648  -0.587  70.054  1.00 51.28  ? 136 GLN B N   1 
ATOM   4817  C CA  . GLN B 1 76  ? -41.042  -2.032  69.959  1.00 54.49  ? 136 GLN B CA  1 
ATOM   4818  C C   . GLN B 1 76  ? -40.248  -2.851  70.992  1.00 53.44  ? 136 GLN B C   1 
ATOM   4819  O O   . GLN B 1 76  ? -40.884  -3.662  71.722  1.00 48.94  ? 136 GLN B O   1 
ATOM   4820  C CB  . GLN B 1 76  ? -40.844  -2.607  68.544  1.00 48.53  ? 136 GLN B CB  1 
ATOM   4821  C CG  . GLN B 1 76  ? -42.018  -2.377  67.609  1.00 43.63  ? 136 GLN B CG  1 
ATOM   4822  C CD  . GLN B 1 76  ? -41.737  -2.813  66.194  1.00 49.94  ? 136 GLN B CD  1 
ATOM   4823  O OE1 . GLN B 1 76  ? -40.586  -2.964  65.781  1.00 57.95  ? 136 GLN B OE1 1 
ATOM   4824  N NE2 . GLN B 1 76  ? -42.801  -3.028  65.429  1.00 47.04  ? 136 GLN B NE2 1 
ATOM   4825  N N   . ILE B 1 77  ? -38.922  -2.634  71.047  1.00 59.68  ? 137 ILE B N   1 
ATOM   4826  C CA  . ILE B 1 77  ? -37.961  -3.334  71.956  1.00 65.14  ? 137 ILE B CA  1 
ATOM   4827  C C   . ILE B 1 77  ? -38.440  -3.105  73.390  1.00 62.64  ? 137 ILE B C   1 
ATOM   4828  O O   . ILE B 1 77  ? -38.637  -4.105  74.131  1.00 62.21  ? 137 ILE B O   1 
ATOM   4829  C CB  . ILE B 1 77  ? -36.523  -2.782  71.774  1.00 75.40  ? 137 ILE B CB  1 
ATOM   4830  C CG1 . ILE B 1 77  ? -35.938  -3.061  70.385  1.00 71.64  ? 137 ILE B CG1 1 
ATOM   4831  C CG2 . ILE B 1 77  ? -35.579  -3.224  72.907  1.00 82.25  ? 137 ILE B CG2 1 
ATOM   4832  C CD1 . ILE B 1 77  ? -35.541  -4.450  70.185  1.00 70.97  ? 137 ILE B CD1 1 
ATOM   4833  N N   . LYS B 1 78  ? -38.611  -1.821  73.740  1.00 64.17  ? 138 LYS B N   1 
ATOM   4834  C CA  . LYS B 1 78  ? -38.993  -1.358  75.101  1.00 64.97  ? 138 LYS B CA  1 
ATOM   4835  C C   . LYS B 1 78  ? -40.270  -2.099  75.501  1.00 60.38  ? 138 LYS B C   1 
ATOM   4836  O O   . LYS B 1 78  ? -40.287  -2.637  76.629  1.00 70.96  ? 138 LYS B O   1 
ATOM   4837  C CB  . LYS B 1 78  ? -39.129  0.172   75.171  1.00 62.02  ? 138 LYS B CB  1 
ATOM   4838  C CG  . LYS B 1 78  ? -38.574  0.750   76.472  1.00 66.59  ? 138 LYS B CG  1 
ATOM   4839  C CD  . LYS B 1 78  ? -39.081  2.103   76.848  1.00 72.25  ? 138 LYS B CD  1 
ATOM   4840  C CE  . LYS B 1 78  ? -39.884  2.065   78.130  1.00 76.52  ? 138 LYS B CE  1 
ATOM   4841  N NZ  . LYS B 1 78  ? -40.713  3.283   78.256  1.00 80.38  ? 138 LYS B NZ  1 
ATOM   4842  N N   . LYS B 1 79  ? -41.247  -2.151  74.586  1.00 54.51  ? 139 LYS B N   1 
ATOM   4843  C CA  . LYS B 1 79  ? -42.598  -2.727  74.797  1.00 57.85  ? 139 LYS B CA  1 
ATOM   4844  C C   . LYS B 1 79  ? -42.487  -4.235  75.035  1.00 51.60  ? 139 LYS B C   1 
ATOM   4845  O O   . LYS B 1 79  ? -43.057  -4.700  76.036  1.00 56.85  ? 139 LYS B O   1 
ATOM   4846  C CB  . LYS B 1 79  ? -43.502  -2.460  73.595  1.00 57.78  ? 139 LYS B CB  1 
ATOM   4847  C CG  . LYS B 1 79  ? -44.979  -2.754  73.841  1.00 59.50  ? 139 LYS B CG  1 
ATOM   4848  C CD  . LYS B 1 79  ? -45.757  -3.074  72.583  1.00 60.09  ? 139 LYS B CD  1 
ATOM   4849  C CE  . LYS B 1 79  ? -46.164  -1.827  71.826  1.00 67.79  ? 139 LYS B CE  1 
ATOM   4850  N NZ  . LYS B 1 79  ? -46.774  -2.148  70.519  1.00 75.87  ? 139 LYS B NZ  1 
ATOM   4851  N N   . PHE B 1 80  ? -41.807  -4.966  74.156  1.00 49.84  ? 140 PHE B N   1 
ATOM   4852  C CA  . PHE B 1 80  ? -41.672  -6.434  74.314  1.00 54.39  ? 140 PHE B CA  1 
ATOM   4853  C C   . PHE B 1 80  ? -40.923  -6.722  75.622  1.00 64.94  ? 140 PHE B C   1 
ATOM   4854  O O   . PHE B 1 80  ? -41.325  -7.672  76.360  1.00 70.72  ? 140 PHE B O   1 
ATOM   4855  C CB  . PHE B 1 80  ? -40.974  -7.108  73.129  1.00 48.47  ? 140 PHE B CB  1 
ATOM   4856  C CG  . PHE B 1 80  ? -41.132  -8.608  73.131  1.00 43.89  ? 140 PHE B CG  1 
ATOM   4857  C CD1 . PHE B 1 80  ? -40.172  -9.433  73.701  1.00 51.56  ? 140 PHE B CD1 1 
ATOM   4858  C CD2 . PHE B 1 80  ? -42.262  -9.206  72.622  1.00 41.57  ? 140 PHE B CD2 1 
ATOM   4859  C CE1 . PHE B 1 80  ? -40.318  -10.820 73.727  1.00 48.36  ? 140 PHE B CE1 1 
ATOM   4860  C CE2 . PHE B 1 80  ? -42.422  -10.588 72.663  1.00 46.21  ? 140 PHE B CE2 1 
ATOM   4861  C CZ  . PHE B 1 80  ? -41.447  -11.395 73.217  1.00 43.62  ? 140 PHE B CZ  1 
ATOM   4862  N N   . MET B 1 81  ? -39.872  -5.939  75.905  1.00 67.69  ? 141 MET B N   1 
ATOM   4863  C CA  . MET B 1 81  ? -39.002  -6.186  77.082  1.00 57.18  ? 141 MET B CA  1 
ATOM   4864  C C   . MET B 1 81  ? -39.889  -6.064  78.314  1.00 52.16  ? 141 MET B C   1 
ATOM   4865  O O   . MET B 1 81  ? -39.891  -6.984  79.160  1.00 64.29  ? 141 MET B O   1 
ATOM   4866  C CB  . MET B 1 81  ? -37.806  -5.228  77.154  1.00 56.04  ? 141 MET B CB  1 
ATOM   4867  C CG  . MET B 1 81  ? -36.603  -5.654  76.297  1.00 60.38  ? 141 MET B CG  1 
ATOM   4868  S SD  . MET B 1 81  ? -36.068  -7.412  76.401  1.00 60.03  ? 141 MET B SD  1 
ATOM   4869  C CE  . MET B 1 81  ? -35.308  -7.490  78.037  1.00 63.98  ? 141 MET B CE  1 
ATOM   4870  N N   . ASN B 1 82  ? -40.692  -5.011  78.363  1.00 51.95  ? 142 ASN B N   1 
ATOM   4871  C CA  . ASN B 1 82  ? -41.561  -4.701  79.521  1.00 56.31  ? 142 ASN B CA  1 
ATOM   4872  C C   . ASN B 1 82  ? -42.463  -5.919  79.801  1.00 57.05  ? 142 ASN B C   1 
ATOM   4873  O O   . ASN B 1 82  ? -42.485  -6.351  80.957  1.00 50.15  ? 142 ASN B O   1 
ATOM   4874  C CB  . ASN B 1 82  ? -42.299  -3.397  79.251  1.00 53.96  ? 142 ASN B CB  1 
ATOM   4875  C CG  . ASN B 1 82  ? -43.253  -3.060  80.346  1.00 59.65  ? 142 ASN B CG  1 
ATOM   4876  O OD1 . ASN B 1 82  ? -42.798  -2.941  81.474  1.00 64.43  ? 142 ASN B OD1 1 
ATOM   4877  N ND2 . ASN B 1 82  ? -44.544  -3.038  80.021  1.00 63.04  ? 142 ASN B ND2 1 
ATOM   4878  N N   . THR B 1 83  ? -43.149  -6.467  78.787  1.00 58.99  ? 143 THR B N   1 
ATOM   4879  C CA  . THR B 1 83  ? -44.093  -7.611  78.935  1.00 61.74  ? 143 THR B CA  1 
ATOM   4880  C C   . THR B 1 83  ? -43.338  -8.940  79.095  1.00 57.98  ? 143 THR B C   1 
ATOM   4881  O O   . THR B 1 83  ? -43.935  -9.916  79.584  1.00 64.27  ? 143 THR B O   1 
ATOM   4882  C CB  . THR B 1 83  ? -45.122  -7.692  77.799  1.00 64.66  ? 143 THR B CB  1 
ATOM   4883  O OG1 . THR B 1 83  ? -44.474  -7.653  76.532  1.00 72.35  ? 143 THR B OG1 1 
ATOM   4884  C CG2 . THR B 1 83  ? -46.142  -6.580  77.872  1.00 68.56  ? 143 THR B CG2 1 
ATOM   4885  N N   . LEU B 1 84  ? -42.069  -9.003  78.728  1.00 53.21  ? 144 LEU B N   1 
ATOM   4886  C CA  . LEU B 1 84  ? -41.300  -10.254 78.905  1.00 55.96  ? 144 LEU B CA  1 
ATOM   4887  C C   . LEU B 1 84  ? -41.033  -10.474 80.395  1.00 55.83  ? 144 LEU B C   1 
ATOM   4888  O O   . LEU B 1 84  ? -41.004  -11.656 80.843  1.00 51.56  ? 144 LEU B O   1 
ATOM   4889  C CB  . LEU B 1 84  ? -40.002  -10.165 78.108  1.00 54.74  ? 144 LEU B CB  1 
ATOM   4890  C CG  . LEU B 1 84  ? -39.198  -11.456 78.115  1.00 56.39  ? 144 LEU B CG  1 
ATOM   4891  C CD1 . LEU B 1 84  ? -39.956  -12.541 77.419  1.00 52.84  ? 144 LEU B CD1 1 
ATOM   4892  C CD2 . LEU B 1 84  ? -37.837  -11.237 77.512  1.00 64.91  ? 144 LEU B CD2 1 
ATOM   4893  N N   . ARG B 1 85  ? -40.821  -9.378  81.129  1.00 58.66  ? 145 ARG B N   1 
ATOM   4894  C CA  . ARG B 1 85  ? -40.382  -9.424  82.550  1.00 62.56  ? 145 ARG B CA  1 
ATOM   4895  C C   . ARG B 1 85  ? -41.569  -9.753  83.466  1.00 66.64  ? 145 ARG B C   1 
ATOM   4896  O O   . ARG B 1 85  ? -41.338  -10.069 84.640  1.00 59.40  ? 145 ARG B O   1 
ATOM   4897  C CB  . ARG B 1 85  ? -39.748  -8.090  82.939  1.00 57.78  ? 145 ARG B CB  1 
ATOM   4898  C CG  . ARG B 1 85  ? -38.453  -7.804  82.197  1.00 57.09  ? 145 ARG B CG  1 
ATOM   4899  C CD  . ARG B 1 85  ? -37.933  -6.445  82.563  1.00 54.59  ? 145 ARG B CD  1 
ATOM   4900  N NE  . ARG B 1 85  ? -36.744  -6.186  81.762  1.00 53.80  ? 145 ARG B NE  1 
ATOM   4901  C CZ  . ARG B 1 85  ? -36.507  -5.070  81.100  1.00 53.62  ? 145 ARG B CZ  1 
ATOM   4902  N NH1 . ARG B 1 85  ? -37.368  -4.067  81.173  1.00 56.41  ? 145 ARG B NH1 1 
ATOM   4903  N NH2 . ARG B 1 85  ? -35.394  -4.938  80.412  1.00 55.99  ? 145 ARG B NH2 1 
ATOM   4904  N N   . GLN B 1 86  ? -42.804  -9.664  82.956  1.00 66.46  ? 146 GLN B N   1 
ATOM   4905  C CA  . GLN B 1 86  ? -44.011  -9.938  83.766  1.00 58.87  ? 146 GLN B CA  1 
ATOM   4906  C C   . GLN B 1 86  ? -44.282  -11.440 83.788  1.00 53.39  ? 146 GLN B C   1 
ATOM   4907  O O   . GLN B 1 86  ? -44.981  -11.864 84.678  1.00 58.08  ? 146 GLN B O   1 
ATOM   4908  C CB  . GLN B 1 86  ? -45.155  -9.070  83.259  1.00 64.37  ? 146 GLN B CB  1 
ATOM   4909  C CG  . GLN B 1 86  ? -44.864  -7.608  83.560  1.00 69.19  ? 146 GLN B CG  1 
ATOM   4910  C CD  . GLN B 1 86  ? -45.947  -6.644  83.162  1.00 76.13  ? 146 GLN B CD  1 
ATOM   4911  O OE1 . GLN B 1 86  ? -45.860  -5.961  82.144  1.00 82.43  ? 146 GLN B OE1 1 
ATOM   4912  N NE2 . GLN B 1 86  ? -46.967  -6.564  83.998  1.00 85.45  ? 146 GLN B NE2 1 
ATOM   4913  N N   . TYR B 1 87  ? -43.731  -12.230 82.870  1.00 53.93  ? 147 TYR B N   1 
ATOM   4914  C CA  . TYR B 1 87  ? -43.797  -13.716 82.949  1.00 56.28  ? 147 TYR B CA  1 
ATOM   4915  C C   . TYR B 1 87  ? -43.009  -14.157 84.191  1.00 57.99  ? 147 TYR B C   1 
ATOM   4916  O O   . TYR B 1 87  ? -41.961  -13.581 84.547  1.00 53.48  ? 147 TYR B O   1 
ATOM   4917  C CB  . TYR B 1 87  ? -43.328  -14.377 81.649  1.00 56.12  ? 147 TYR B CB  1 
ATOM   4918  C CG  . TYR B 1 87  ? -44.248  -14.133 80.481  1.00 61.68  ? 147 TYR B CG  1 
ATOM   4919  C CD1 . TYR B 1 87  ? -45.431  -14.845 80.360  1.00 60.48  ? 147 TYR B CD1 1 
ATOM   4920  C CD2 . TYR B 1 87  ? -43.977  -13.162 79.525  1.00 69.02  ? 147 TYR B CD2 1 
ATOM   4921  C CE1 . TYR B 1 87  ? -46.305  -14.640 79.301  1.00 58.93  ? 147 TYR B CE1 1 
ATOM   4922  C CE2 . TYR B 1 87  ? -44.859  -12.920 78.475  1.00 75.49  ? 147 TYR B CE2 1 
ATOM   4923  C CZ  . TYR B 1 87  ? -46.024  -13.670 78.359  1.00 69.33  ? 147 TYR B CZ  1 
ATOM   4924  O OH  . TYR B 1 87  ? -46.896  -13.499 77.321  1.00 68.35  ? 147 TYR B OH  1 
ATOM   4925  N N   . GLN B 1 88  ? -43.532  -15.179 84.847  1.00 59.29  ? 148 GLN B N   1 
ATOM   4926  C CA  . GLN B 1 88  ? -43.089  -15.644 86.167  1.00 60.51  ? 148 GLN B CA  1 
ATOM   4927  C C   . GLN B 1 88  ? -41.973  -16.669 86.004  1.00 57.14  ? 148 GLN B C   1 
ATOM   4928  O O   . GLN B 1 88  ? -41.111  -16.742 86.905  1.00 66.80  ? 148 GLN B O   1 
ATOM   4929  C CB  . GLN B 1 88  ? -44.301  -16.181 86.944  1.00 69.22  ? 148 GLN B CB  1 
ATOM   4930  C CG  . GLN B 1 88  ? -44.901  -15.151 87.902  1.00 80.88  ? 148 GLN B CG  1 
ATOM   4931  C CD  . GLN B 1 88  ? -45.534  -13.989 87.173  1.00 87.42  ? 148 GLN B CD  1 
ATOM   4932  O OE1 . GLN B 1 88  ? -45.232  -12.818 87.439  1.00 82.12  ? 148 GLN B OE1 1 
ATOM   4933  N NE2 . GLN B 1 88  ? -46.371  -14.322 86.198  1.00 79.50  ? 148 GLN B NE2 1 
ATOM   4934  N N   . THR B 1 89  ? -42.013  -17.508 84.976  1.00 54.36  ? 149 THR B N   1 
ATOM   4935  C CA  . THR B 1 89  ? -41.013  -18.605 84.833  1.00 60.89  ? 149 THR B CA  1 
ATOM   4936  C C   . THR B 1 89  ? -40.032  -18.206 83.731  1.00 58.27  ? 149 THR B C   1 
ATOM   4937  O O   . THR B 1 89  ? -40.341  -17.339 82.922  1.00 51.03  ? 149 THR B O   1 
ATOM   4938  C CB  . THR B 1 89  ? -41.679  -19.989 84.706  1.00 57.45  ? 149 THR B CB  1 
ATOM   4939  O OG1 . THR B 1 89  ? -42.152  -20.196 83.384  1.00 68.50  ? 149 THR B OG1 1 
ATOM   4940  C CG2 . THR B 1 89  ? -42.843  -20.140 85.652  1.00 60.41  ? 149 THR B CG2 1 
ATOM   4941  N N   . PRO B 1 90  ? -38.785  -18.732 83.728  1.00 67.35  ? 150 PRO B N   1 
ATOM   4942  C CA  . PRO B 1 90  ? -37.888  -18.550 82.581  1.00 65.15  ? 150 PRO B CA  1 
ATOM   4943  C C   . PRO B 1 90  ? -38.476  -19.184 81.308  1.00 63.07  ? 150 PRO B C   1 
ATOM   4944  O O   . PRO B 1 90  ? -38.498  -18.496 80.316  1.00 63.21  ? 150 PRO B O   1 
ATOM   4945  C CB  . PRO B 1 90  ? -36.567  -19.228 82.976  1.00 61.82  ? 150 PRO B CB  1 
ATOM   4946  C CG  . PRO B 1 90  ? -36.714  -19.628 84.457  1.00 61.86  ? 150 PRO B CG  1 
ATOM   4947  C CD  . PRO B 1 90  ? -38.165  -19.474 84.842  1.00 60.77  ? 150 PRO B CD  1 
ATOM   4948  N N   . LEU B 1 91  ? -38.958  -20.444 81.392  1.00 58.09  ? 151 LEU B N   1 
ATOM   4949  C CA  . LEU B 1 91  ? -39.620  -21.188 80.282  1.00 45.54  ? 151 LEU B CA  1 
ATOM   4950  C C   . LEU B 1 91  ? -40.681  -20.307 79.607  1.00 43.16  ? 151 LEU B C   1 
ATOM   4951  O O   . LEU B 1 91  ? -40.704  -20.264 78.403  1.00 48.47  ? 151 LEU B O   1 
ATOM   4952  C CB  . LEU B 1 91  ? -40.256  -22.467 80.829  1.00 40.87  ? 151 LEU B CB  1 
ATOM   4953  C CG  . LEU B 1 91  ? -40.876  -23.384 79.775  1.00 43.77  ? 151 LEU B CG  1 
ATOM   4954  C CD1 . LEU B 1 91  ? -39.881  -23.651 78.643  1.00 52.20  ? 151 LEU B CD1 1 
ATOM   4955  C CD2 . LEU B 1 91  ? -41.309  -24.700 80.388  1.00 45.17  ? 151 LEU B CD2 1 
ATOM   4956  N N   . GLN B 1 92  ? -41.512  -19.587 80.354  1.00 46.07  ? 152 GLN B N   1 
ATOM   4957  C CA  . GLN B 1 92  ? -42.506  -18.632 79.789  1.00 46.94  ? 152 GLN B CA  1 
ATOM   4958  C C   . GLN B 1 92  ? -41.814  -17.520 78.985  1.00 48.62  ? 152 GLN B C   1 
ATOM   4959  O O   . GLN B 1 92  ? -42.378  -17.137 77.972  1.00 53.85  ? 152 GLN B O   1 
ATOM   4960  C CB  . GLN B 1 92  ? -43.382  -18.014 80.883  1.00 47.64  ? 152 GLN B CB  1 
ATOM   4961  C CG  . GLN B 1 92  ? -44.495  -18.942 81.339  1.00 51.20  ? 152 GLN B CG  1 
ATOM   4962  C CD  . GLN B 1 92  ? -45.146  -18.492 82.616  1.00 50.26  ? 152 GLN B CD  1 
ATOM   4963  O OE1 . GLN B 1 92  ? -44.948  -17.376 83.088  1.00 55.69  ? 152 GLN B OE1 1 
ATOM   4964  N NE2 . GLN B 1 92  ? -45.932  -19.389 83.180  1.00 59.78  ? 152 GLN B NE2 1 
ATOM   4965  N N   . ARG B 1 93  ? -40.653  -17.014 79.401  1.00 46.32  ? 153 ARG B N   1 
ATOM   4966  C CA  . ARG B 1 93  ? -39.922  -15.984 78.619  1.00 46.72  ? 153 ARG B CA  1 
ATOM   4967  C C   . ARG B 1 93  ? -39.271  -16.619 77.384  1.00 47.06  ? 153 ARG B C   1 
ATOM   4968  O O   . ARG B 1 93  ? -39.135  -15.891 76.356  1.00 46.02  ? 153 ARG B O   1 
ATOM   4969  C CB  . ARG B 1 93  ? -38.873  -15.293 79.486  1.00 51.47  ? 153 ARG B CB  1 
ATOM   4970  C CG  . ARG B 1 93  ? -39.421  -14.536 80.691  1.00 53.51  ? 153 ARG B CG  1 
ATOM   4971  C CD  . ARG B 1 93  ? -38.651  -14.901 81.968  1.00 56.46  ? 153 ARG B CD  1 
ATOM   4972  N NE  . ARG B 1 93  ? -39.063  -14.115 83.108  1.00 58.71  ? 153 ARG B NE  1 
ATOM   4973  C CZ  . ARG B 1 93  ? -38.587  -12.903 83.382  1.00 66.87  ? 153 ARG B CZ  1 
ATOM   4974  N NH1 . ARG B 1 93  ? -37.693  -12.329 82.587  1.00 65.64  ? 153 ARG B NH1 1 
ATOM   4975  N NH2 . ARG B 1 93  ? -39.033  -12.251 84.433  1.00 74.37  ? 153 ARG B NH2 1 
ATOM   4976  N N   . TYR B 1 94  ? -38.895  -17.908 77.441  1.00 44.18  ? 154 TYR B N   1 
ATOM   4977  C CA  . TYR B 1 94  ? -38.389  -18.675 76.266  1.00 44.22  ? 154 TYR B CA  1 
ATOM   4978  C C   . TYR B 1 94  ? -39.496  -18.803 75.220  1.00 45.96  ? 154 TYR B C   1 
ATOM   4979  O O   . TYR B 1 94  ? -39.204  -18.643 74.024  1.00 55.41  ? 154 TYR B O   1 
ATOM   4980  C CB  . TYR B 1 94  ? -37.891  -20.082 76.640  1.00 52.39  ? 154 TYR B CB  1 
ATOM   4981  C CG  . TYR B 1 94  ? -37.569  -20.978 75.464  1.00 43.61  ? 154 TYR B CG  1 
ATOM   4982  C CD1 . TYR B 1 94  ? -38.502  -21.874 75.002  1.00 41.80  ? 154 TYR B CD1 1 
ATOM   4983  C CD2 . TYR B 1 94  ? -36.368  -20.895 74.795  1.00 39.57  ? 154 TYR B CD2 1 
ATOM   4984  C CE1 . TYR B 1 94  ? -38.248  -22.667 73.898  1.00 45.75  ? 154 TYR B CE1 1 
ATOM   4985  C CE2 . TYR B 1 94  ? -36.090  -21.701 73.709  1.00 45.64  ? 154 TYR B CE2 1 
ATOM   4986  C CZ  . TYR B 1 94  ? -37.031  -22.595 73.249  1.00 46.55  ? 154 TYR B CZ  1 
ATOM   4987  O OH  . TYR B 1 94  ? -36.748  -23.378 72.159  1.00 44.57  ? 154 TYR B OH  1 
ATOM   4988  N N   . ILE B 1 95  ? -40.713  -19.115 75.661  1.00 44.28  ? 155 ILE B N   1 
ATOM   4989  C CA  . ILE B 1 95  ? -41.882  -19.298 74.758  1.00 47.22  ? 155 ILE B CA  1 
ATOM   4990  C C   . ILE B 1 95  ? -42.176  -17.948 74.101  1.00 45.50  ? 155 ILE B C   1 
ATOM   4991  O O   . ILE B 1 95  ? -42.429  -17.946 72.885  1.00 48.34  ? 155 ILE B O   1 
ATOM   4992  C CB  . ILE B 1 95  ? -43.105  -19.901 75.483  1.00 51.80  ? 155 ILE B CB  1 
ATOM   4993  C CG1 . ILE B 1 95  ? -42.769  -21.314 75.995  1.00 53.02  ? 155 ILE B CG1 1 
ATOM   4994  C CG2 . ILE B 1 95  ? -44.336  -19.919 74.571  1.00 55.83  ? 155 ILE B CG2 1 
ATOM   4995  C CD1 . ILE B 1 95  ? -43.961  -22.139 76.494  1.00 48.74  ? 155 ILE B CD1 1 
ATOM   4996  N N   . ALA B 1 96  ? -42.122  -16.848 74.855  1.00 41.85  ? 156 ALA B N   1 
ATOM   4997  C CA  . ALA B 1 96  ? -42.433  -15.502 74.332  1.00 45.68  ? 156 ALA B CA  1 
ATOM   4998  C C   . ALA B 1 96  ? -41.354  -15.090 73.338  1.00 45.88  ? 156 ALA B C   1 
ATOM   4999  O O   . ALA B 1 96  ? -41.689  -14.361 72.380  1.00 51.38  ? 156 ALA B O   1 
ATOM   5000  C CB  . ALA B 1 96  ? -42.586  -14.493 75.445  1.00 49.77  ? 156 ALA B CB  1 
ATOM   5001  N N   . MET B 1 97  ? -40.113  -15.543 73.543  1.00 46.06  ? 157 MET B N   1 
ATOM   5002  C CA  . MET B 1 97  ? -38.971  -15.189 72.657  1.00 46.78  ? 157 MET B CA  1 
ATOM   5003  C C   . MET B 1 97  ? -39.126  -15.947 71.333  1.00 50.10  ? 157 MET B C   1 
ATOM   5004  O O   . MET B 1 97  ? -39.033  -15.291 70.294  1.00 54.57  ? 157 MET B O   1 
ATOM   5005  C CB  . MET B 1 97  ? -37.633  -15.496 73.330  1.00 41.35  ? 157 MET B CB  1 
ATOM   5006  C CG  . MET B 1 97  ? -37.203  -14.412 74.327  1.00 46.83  ? 157 MET B CG  1 
ATOM   5007  S SD  . MET B 1 97  ? -36.953  -12.713 73.589  1.00 51.71  ? 157 MET B SD  1 
ATOM   5008  C CE  . MET B 1 97  ? -35.553  -13.008 72.535  1.00 44.28  ? 157 MET B CE  1 
ATOM   5009  N N   . MET B 1 98  ? -39.445  -17.248 71.378  1.00 54.60  ? 158 MET B N   1 
ATOM   5010  C CA  . MET B 1 98  ? -39.579  -18.130 70.183  1.00 59.08  ? 158 MET B CA  1 
ATOM   5011  C C   . MET B 1 98  ? -40.784  -17.689 69.347  1.00 64.58  ? 158 MET B C   1 
ATOM   5012  O O   . MET B 1 98  ? -40.640  -17.599 68.131  1.00 74.86  ? 158 MET B O   1 
ATOM   5013  C CB  . MET B 1 98  ? -39.681  -19.614 70.563  1.00 55.40  ? 158 MET B CB  1 
ATOM   5014  C CG  . MET B 1 98  ? -38.361  -20.164 71.125  1.00 55.17  ? 158 MET B CG  1 
ATOM   5015  S SD  . MET B 1 98  ? -36.932  -19.651 70.110  1.00 68.82  ? 158 MET B SD  1 
ATOM   5016  C CE  . MET B 1 98  ? -35.835  -19.014 71.366  1.00 72.09  ? 158 MET B CE  1 
ATOM   5017  N N   . ASN B 1 99  ? -41.898  -17.356 69.987  1.00 72.87  ? 159 ASN B N   1 
ATOM   5018  C CA  . ASN B 1 99  ? -43.085  -16.707 69.353  1.00 71.09  ? 159 ASN B CA  1 
ATOM   5019  C C   . ASN B 1 99  ? -42.662  -15.452 68.556  1.00 64.11  ? 159 ASN B C   1 
ATOM   5020  O O   . ASN B 1 99  ? -43.055  -15.357 67.392  1.00 68.12  ? 159 ASN B O   1 
ATOM   5021  C CB  . ASN B 1 99  ? -44.152  -16.342 70.390  1.00 86.43  ? 159 ASN B CB  1 
ATOM   5022  C CG  . ASN B 1 99  ? -45.536  -16.868 70.081  1.00 97.56  ? 159 ASN B CG  1 
ATOM   5023  O OD1 . ASN B 1 99  ? -46.127  -16.548 69.043  1.00 112.52 ? 159 ASN B OD1 1 
ATOM   5024  N ND2 . ASN B 1 99  ? -46.058  -17.670 71.005  1.00 110.74 ? 159 ASN B ND2 1 
ATOM   5025  N N   . LEU B 1 100 ? -41.887  -14.520 69.128  1.00 57.22  ? 160 LEU B N   1 
ATOM   5026  C CA  . LEU B 1 100 ? -41.432  -13.277 68.443  1.00 52.52  ? 160 LEU B CA  1 
ATOM   5027  C C   . LEU B 1 100 ? -40.509  -13.620 67.265  1.00 55.30  ? 160 LEU B C   1 
ATOM   5028  O O   . LEU B 1 100 ? -40.692  -13.039 66.167  1.00 48.60  ? 160 LEU B O   1 
ATOM   5029  C CB  . LEU B 1 100 ? -40.705  -12.384 69.452  1.00 54.17  ? 160 LEU B CB  1 
ATOM   5030  C CG  . LEU B 1 100 ? -40.116  -11.086 68.895  1.00 49.26  ? 160 LEU B CG  1 
ATOM   5031  C CD1 . LEU B 1 100 ? -41.167  -10.156 68.302  1.00 46.80  ? 160 LEU B CD1 1 
ATOM   5032  C CD2 . LEU B 1 100 ? -39.367  -10.368 69.992  1.00 51.61  ? 160 LEU B CD2 1 
ATOM   5033  N N   . GLN B 1 101 ? -39.549  -14.532 67.462  1.00 56.70  ? 161 GLN B N   1 
ATOM   5034  C CA  . GLN B 1 101 ? -38.650  -15.020 66.370  1.00 57.43  ? 161 GLN B CA  1 
ATOM   5035  C C   . GLN B 1 101 ? -39.515  -15.366 65.149  1.00 54.37  ? 161 GLN B C   1 
ATOM   5036  O O   . GLN B 1 101 ? -39.080  -15.008 64.020  1.00 54.94  ? 161 GLN B O   1 
ATOM   5037  C CB  . GLN B 1 101 ? -37.820  -16.233 66.806  1.00 55.65  ? 161 GLN B CB  1 
ATOM   5038  C CG  . GLN B 1 101 ? -37.042  -16.918 65.696  1.00 50.66  ? 161 GLN B CG  1 
ATOM   5039  C CD  . GLN B 1 101 ? -35.915  -17.794 66.172  1.00 57.09  ? 161 GLN B CD  1 
ATOM   5040  O OE1 . GLN B 1 101 ? -34.821  -17.769 65.613  1.00 57.89  ? 161 GLN B OE1 1 
ATOM   5041  N NE2 . GLN B 1 101 ? -36.119  -18.512 67.266  1.00 66.35  ? 161 GLN B NE2 1 
ATOM   5042  N N   . GLU B 1 102 ? -40.683  -15.992 65.389  1.00 50.76  ? 162 GLU B N   1 
ATOM   5043  C CA  . GLU B 1 102 ? -41.569  -16.561 64.340  1.00 53.22  ? 162 GLU B CA  1 
ATOM   5044  C C   . GLU B 1 102 ? -42.743  -15.619 64.017  1.00 47.19  ? 162 GLU B C   1 
ATOM   5045  O O   . GLU B 1 102 ? -43.768  -16.136 63.536  1.00 41.85  ? 162 GLU B O   1 
ATOM   5046  C CB  . GLU B 1 102 ? -42.090  -17.931 64.778  1.00 63.54  ? 162 GLU B CB  1 
ATOM   5047  C CG  . GLU B 1 102 ? -40.999  -18.952 65.080  1.00 77.99  ? 162 GLU B CG  1 
ATOM   5048  C CD  . GLU B 1 102 ? -40.053  -19.297 63.938  1.00 83.88  ? 162 GLU B CD  1 
ATOM   5049  O OE1 . GLU B 1 102 ? -40.551  -19.852 62.943  1.00 96.63  ? 162 GLU B OE1 1 
ATOM   5050  O OE2 . GLU B 1 102 ? -38.822  -19.033 64.049  1.00 72.18  ? 162 GLU B OE2 1 
ATOM   5051  N N   . THR B 1 103 ? -42.632  -14.303 64.260  1.00 47.20  ? 163 THR B N   1 
ATOM   5052  C CA  . THR B 1 103 ? -43.659  -13.303 63.849  1.00 47.78  ? 163 THR B CA  1 
ATOM   5053  C C   . THR B 1 103 ? -43.000  -12.043 63.291  1.00 48.20  ? 163 THR B C   1 
ATOM   5054  O O   . THR B 1 103 ? -43.586  -11.451 62.344  1.00 44.12  ? 163 THR B O   1 
ATOM   5055  C CB  . THR B 1 103 ? -44.650  -12.941 64.971  1.00 52.72  ? 163 THR B CB  1 
ATOM   5056  O OG1 . THR B 1 103 ? -44.095  -12.042 65.922  1.00 63.19  ? 163 THR B OG1 1 
ATOM   5057  C CG2 . THR B 1 103 ? -45.173  -14.137 65.734  1.00 55.06  ? 163 THR B CG2 1 
ATOM   5058  N N   . ASP B 1 104 ? -41.882  -11.627 63.897  1.00 52.35  ? 164 ASP B N   1 
ATOM   5059  C CA  . ASP B 1 104 ? -41.050  -10.466 63.486  1.00 53.29  ? 164 ASP B CA  1 
ATOM   5060  C C   . ASP B 1 104 ? -39.585  -10.812 63.799  1.00 57.13  ? 164 ASP B C   1 
ATOM   5061  O O   . ASP B 1 104 ? -39.127  -10.608 64.936  1.00 53.53  ? 164 ASP B O   1 
ATOM   5062  C CB  . ASP B 1 104 ? -41.535  -9.178  64.149  1.00 48.16  ? 164 ASP B CB  1 
ATOM   5063  C CG  . ASP B 1 104 ? -40.810  -7.926  63.672  1.00 51.58  ? 164 ASP B CG  1 
ATOM   5064  O OD1 . ASP B 1 104 ? -39.754  -8.033  62.977  1.00 42.93  ? 164 ASP B OD1 1 
ATOM   5065  O OD2 . ASP B 1 104 ? -41.291  -6.838  64.027  1.00 53.98  ? 164 ASP B OD2 1 
ATOM   5066  N N   . GLU B 1 105 ? -38.879  -11.322 62.791  1.00 60.44  ? 165 GLU B N   1 
ATOM   5067  C CA  . GLU B 1 105 ? -37.501  -11.864 62.876  1.00 55.98  ? 165 GLU B CA  1 
ATOM   5068  C C   . GLU B 1 105 ? -36.542  -10.696 63.113  1.00 55.17  ? 165 GLU B C   1 
ATOM   5069  O O   . GLU B 1 105 ? -35.630  -10.829 63.949  1.00 56.04  ? 165 GLU B O   1 
ATOM   5070  C CB  . GLU B 1 105 ? -37.267  -12.606 61.563  1.00 64.65  ? 165 GLU B CB  1 
ATOM   5071  C CG  . GLU B 1 105 ? -35.909  -13.216 61.345  1.00 65.88  ? 165 GLU B CG  1 
ATOM   5072  C CD  . GLU B 1 105 ? -35.708  -13.470 59.855  1.00 67.19  ? 165 GLU B CD  1 
ATOM   5073  O OE1 . GLU B 1 105 ? -35.348  -12.492 59.124  1.00 58.90  ? 165 GLU B OE1 1 
ATOM   5074  O OE2 . GLU B 1 105 ? -35.966  -14.619 59.416  1.00 60.60  ? 165 GLU B OE2 1 
ATOM   5075  N N   . ARG B 1 106 ? -36.760  -9.568  62.448  1.00 51.76  ? 166 ARG B N   1 
ATOM   5076  C CA  . ARG B 1 106 ? -35.872  -8.384  62.616  1.00 52.30  ? 166 ARG B CA  1 
ATOM   5077  C C   . ARG B 1 106 ? -35.989  -7.791  64.028  1.00 48.56  ? 166 ARG B C   1 
ATOM   5078  O O   . ARG B 1 106 ? -34.963  -7.414  64.609  1.00 41.05  ? 166 ARG B O   1 
ATOM   5079  C CB  . ARG B 1 106 ? -36.237  -7.304  61.604  1.00 68.70  ? 166 ARG B CB  1 
ATOM   5080  C CG  . ARG B 1 106 ? -36.325  -7.774  60.167  1.00 75.94  ? 166 ARG B CG  1 
ATOM   5081  C CD  . ARG B 1 106 ? -34.956  -8.137  59.733  1.00 75.58  ? 166 ARG B CD  1 
ATOM   5082  N NE  . ARG B 1 106 ? -34.281  -6.927  59.362  1.00 72.72  ? 166 ARG B NE  1 
ATOM   5083  C CZ  . ARG B 1 106 ? -33.749  -6.748  58.175  1.00 88.46  ? 166 ARG B CZ  1 
ATOM   5084  N NH1 . ARG B 1 106 ? -33.121  -5.618  57.913  1.00 112.05 ? 166 ARG B NH1 1 
ATOM   5085  N NH2 . ARG B 1 106 ? -33.817  -7.696  57.255  1.00 85.64  ? 166 ARG B NH2 1 
ATOM   5086  N N   . LEU B 1 107 ? -37.197  -7.706  64.591  1.00 56.69  ? 167 LEU B N   1 
ATOM   5087  C CA  . LEU B 1 107 ? -37.397  -7.202  65.980  1.00 53.94  ? 167 LEU B CA  1 
ATOM   5088  C C   . LEU B 1 107 ? -36.764  -8.194  66.964  1.00 45.89  ? 167 LEU B C   1 
ATOM   5089  O O   . LEU B 1 107 ? -36.101  -7.754  67.885  1.00 43.18  ? 167 LEU B O   1 
ATOM   5090  C CB  . LEU B 1 107 ? -38.893  -7.026  66.261  1.00 57.44  ? 167 LEU B CB  1 
ATOM   5091  C CG  . LEU B 1 107 ? -39.229  -6.571  67.677  1.00 57.94  ? 167 LEU B CG  1 
ATOM   5092  C CD1 . LEU B 1 107 ? -38.541  -5.242  67.977  1.00 65.61  ? 167 LEU B CD1 1 
ATOM   5093  C CD2 . LEU B 1 107 ? -40.736  -6.463  67.880  1.00 53.04  ? 167 LEU B CD2 1 
ATOM   5094  N N   . PHE B 1 108 ? -36.961  -9.493  66.751  1.00 41.62  ? 168 PHE B N   1 
ATOM   5095  C CA  . PHE B 1 108 ? -36.412  -10.583 67.590  1.00 39.55  ? 168 PHE B CA  1 
ATOM   5096  C C   . PHE B 1 108 ? -34.898  -10.463 67.663  1.00 44.23  ? 168 PHE B C   1 
ATOM   5097  O O   . PHE B 1 108 ? -34.365  -10.590 68.770  1.00 46.96  ? 168 PHE B O   1 
ATOM   5098  C CB  . PHE B 1 108 ? -36.769  -11.943 67.013  1.00 46.45  ? 168 PHE B CB  1 
ATOM   5099  C CG  . PHE B 1 108 ? -35.997  -13.081 67.603  1.00 47.79  ? 168 PHE B CG  1 
ATOM   5100  C CD1 . PHE B 1 108 ? -36.430  -13.675 68.762  1.00 53.78  ? 168 PHE B CD1 1 
ATOM   5101  C CD2 . PHE B 1 108 ? -34.857  -13.563 66.996  1.00 53.34  ? 168 PHE B CD2 1 
ATOM   5102  C CE1 . PHE B 1 108 ? -35.741  -14.743 69.323  1.00 64.16  ? 168 PHE B CE1 1 
ATOM   5103  C CE2 . PHE B 1 108 ? -34.148  -14.601 67.578  1.00 67.77  ? 168 PHE B CE2 1 
ATOM   5104  C CZ  . PHE B 1 108 ? -34.592  -15.200 68.740  1.00 66.29  ? 168 PHE B CZ  1 
ATOM   5105  N N   . TYR B 1 109 ? -34.210  -10.278 66.530  1.00 47.60  ? 169 TYR B N   1 
ATOM   5106  C CA  . TYR B 1 109 ? -32.719  -10.209 66.530  1.00 42.91  ? 169 TYR B CA  1 
ATOM   5107  C C   . TYR B 1 109 ? -32.266  -8.847  67.094  1.00 42.79  ? 169 TYR B C   1 
ATOM   5108  O O   . TYR B 1 109 ? -31.443  -8.848  68.003  1.00 39.63  ? 169 TYR B O   1 
ATOM   5109  C CB  . TYR B 1 109 ? -32.125  -10.588 65.177  1.00 39.56  ? 169 TYR B CB  1 
ATOM   5110  C CG  . TYR B 1 109 ? -32.238  -12.063 64.889  1.00 38.59  ? 169 TYR B CG  1 
ATOM   5111  C CD1 . TYR B 1 109 ? -31.597  -12.994 65.679  1.00 38.87  ? 169 TYR B CD1 1 
ATOM   5112  C CD2 . TYR B 1 109 ? -33.033  -12.547 63.865  1.00 41.36  ? 169 TYR B CD2 1 
ATOM   5113  C CE1 . TYR B 1 109 ? -31.697  -14.357 65.437  1.00 35.14  ? 169 TYR B CE1 1 
ATOM   5114  C CE2 . TYR B 1 109 ? -33.142  -13.912 63.610  1.00 43.09  ? 169 TYR B CE2 1 
ATOM   5115  C CZ  . TYR B 1 109 ? -32.468  -14.820 64.404  1.00 35.83  ? 169 TYR B CZ  1 
ATOM   5116  O OH  . TYR B 1 109 ? -32.587  -16.145 64.176  1.00 37.11  ? 169 TYR B OH  1 
ATOM   5117  N N   . LYS B 1 110 ? -32.848  -7.722  66.675  1.00 46.88  ? 170 LYS B N   1 
ATOM   5118  C CA  . LYS B 1 110 ? -32.439  -6.374  67.186  1.00 47.26  ? 170 LYS B CA  1 
ATOM   5119  C C   . LYS B 1 110 ? -32.679  -6.314  68.712  1.00 51.49  ? 170 LYS B C   1 
ATOM   5120  O O   . LYS B 1 110 ? -31.909  -5.696  69.437  1.00 55.16  ? 170 LYS B O   1 
ATOM   5121  C CB  . LYS B 1 110 ? -33.213  -5.300  66.439  1.00 50.80  ? 170 LYS B CB  1 
ATOM   5122  C CG  . LYS B 1 110 ? -32.961  -3.893  66.932  1.00 57.33  ? 170 LYS B CG  1 
ATOM   5123  C CD  . LYS B 1 110 ? -31.847  -3.176  66.218  1.00 62.59  ? 170 LYS B CD  1 
ATOM   5124  C CE  . LYS B 1 110 ? -32.156  -1.711  65.952  1.00 62.20  ? 170 LYS B CE  1 
ATOM   5125  N NZ  . LYS B 1 110 ? -32.703  -1.069  67.175  1.00 74.01  ? 170 LYS B NZ  1 
ATOM   5126  N N   . LEU B 1 111 ? -33.713  -6.984  69.217  1.00 50.50  ? 171 LEU B N   1 
ATOM   5127  C CA  . LEU B 1 111 ? -33.995  -7.080  70.674  1.00 52.37  ? 171 LEU B CA  1 
ATOM   5128  C C   . LEU B 1 111 ? -32.905  -7.915  71.333  1.00 54.60  ? 171 LEU B C   1 
ATOM   5129  O O   . LEU B 1 111 ? -32.246  -7.378  72.241  1.00 53.52  ? 171 LEU B O   1 
ATOM   5130  C CB  . LEU B 1 111 ? -35.394  -7.662  70.869  1.00 51.04  ? 171 LEU B CB  1 
ATOM   5131  C CG  . LEU B 1 111 ? -35.829  -7.952  72.295  1.00 53.18  ? 171 LEU B CG  1 
ATOM   5132  C CD1 . LEU B 1 111 ? -37.120  -7.197  72.589  1.00 55.69  ? 171 LEU B CD1 1 
ATOM   5133  C CD2 . LEU B 1 111 ? -36.007  -9.459  72.531  1.00 49.04  ? 171 LEU B CD2 1 
ATOM   5134  N N   . LEU B 1 112 ? -32.710  -9.151  70.871  1.00 56.35  ? 172 LEU B N   1 
ATOM   5135  C CA  . LEU B 1 112 ? -31.663  -10.099 71.388  1.00 56.46  ? 172 LEU B CA  1 
ATOM   5136  C C   . LEU B 1 112 ? -30.298  -9.389  71.497  1.00 51.23  ? 172 LEU B C   1 
ATOM   5137  O O   . LEU B 1 112 ? -29.717  -9.468  72.563  1.00 45.68  ? 172 LEU B O   1 
ATOM   5138  C CB  . LEU B 1 112 ? -31.543  -11.318 70.458  1.00 52.46  ? 172 LEU B CB  1 
ATOM   5139  C CG  . LEU B 1 112 ? -31.468  -12.695 71.101  1.00 53.06  ? 172 LEU B CG  1 
ATOM   5140  C CD1 . LEU B 1 112 ? -30.804  -13.657 70.162  1.00 61.05  ? 172 LEU B CD1 1 
ATOM   5141  C CD2 . LEU B 1 112 ? -30.737  -12.688 72.421  1.00 51.90  ? 172 LEU B CD2 1 
ATOM   5142  N N   . ILE B 1 113 ? -29.822  -8.704  70.448  1.00 52.82  ? 173 ILE B N   1 
ATOM   5143  C CA  . ILE B 1 113 ? -28.525  -7.962  70.454  1.00 55.80  ? 173 ILE B CA  1 
ATOM   5144  C C   . ILE B 1 113 ? -28.551  -6.925  71.584  1.00 54.03  ? 173 ILE B C   1 
ATOM   5145  O O   . ILE B 1 113 ? -27.696  -7.044  72.510  1.00 52.91  ? 173 ILE B O   1 
ATOM   5146  C CB  . ILE B 1 113 ? -28.214  -7.270  69.096  1.00 59.59  ? 173 ILE B CB  1 
ATOM   5147  C CG1 . ILE B 1 113 ? -28.178  -8.204  67.887  1.00 59.66  ? 173 ILE B CG1 1 
ATOM   5148  C CG2 . ILE B 1 113 ? -26.929  -6.450  69.171  1.00 56.08  ? 173 ILE B CG2 1 
ATOM   5149  C CD1 . ILE B 1 113 ? -27.311  -9.389  68.051  1.00 62.91  ? 173 ILE B CD1 1 
ATOM   5150  N N   . ASP B 1 114 ? -29.503  -5.977  71.543  1.00 50.68  ? 174 ASP B N   1 
ATOM   5151  C CA  . ASP B 1 114 ? -29.518  -4.800  72.450  1.00 52.56  ? 174 ASP B CA  1 
ATOM   5152  C C   . ASP B 1 114 ? -29.666  -5.238  73.911  1.00 52.85  ? 174 ASP B C   1 
ATOM   5153  O O   . ASP B 1 114 ? -29.458  -4.387  74.778  1.00 55.86  ? 174 ASP B O   1 
ATOM   5154  C CB  . ASP B 1 114 ? -30.642  -3.822  72.103  1.00 58.06  ? 174 ASP B CB  1 
ATOM   5155  C CG  . ASP B 1 114 ? -30.517  -3.210  70.724  1.00 62.95  ? 174 ASP B CG  1 
ATOM   5156  O OD1 . ASP B 1 114 ? -29.517  -3.516  70.042  1.00 62.96  ? 174 ASP B OD1 1 
ATOM   5157  O OD2 . ASP B 1 114 ? -31.427  -2.456  70.342  1.00 62.90  ? 174 ASP B OD2 1 
ATOM   5158  N N   . ASN B 1 115 ? -30.054  -6.490  74.177  1.00 55.05  ? 175 ASN B N   1 
ATOM   5159  C CA  . ASN B 1 115 ? -30.394  -6.999  75.534  1.00 53.61  ? 175 ASN B CA  1 
ATOM   5160  C C   . ASN B 1 115 ? -29.726  -8.364  75.739  1.00 55.45  ? 175 ASN B C   1 
ATOM   5161  O O   . ASN B 1 115 ? -30.306  -9.202  76.451  1.00 50.87  ? 175 ASN B O   1 
ATOM   5162  C CB  . ASN B 1 115 ? -31.913  -7.061  75.735  1.00 50.99  ? 175 ASN B CB  1 
ATOM   5163  C CG  . ASN B 1 115 ? -32.567  -5.700  75.699  1.00 54.46  ? 175 ASN B CG  1 
ATOM   5164  O OD1 . ASN B 1 115 ? -32.563  -4.965  76.681  1.00 58.11  ? 175 ASN B OD1 1 
ATOM   5165  N ND2 . ASN B 1 115 ? -33.125  -5.349  74.559  1.00 64.88  ? 175 ASN B ND2 1 
ATOM   5166  N N   . VAL B 1 116 ? -28.537  -8.565  75.164  1.00 57.68  ? 176 VAL B N   1 
ATOM   5167  C CA  . VAL B 1 116 ? -27.944  -9.931  74.989  1.00 62.33  ? 176 VAL B CA  1 
ATOM   5168  C C   . VAL B 1 116 ? -27.620  -10.582 76.346  1.00 60.85  ? 176 VAL B C   1 
ATOM   5169  O O   . VAL B 1 116 ? -27.775  -11.825 76.453  1.00 56.31  ? 176 VAL B O   1 
ATOM   5170  C CB  . VAL B 1 116 ? -26.718  -9.913  74.058  1.00 58.71  ? 176 VAL B CB  1 
ATOM   5171  C CG1 . VAL B 1 116 ? -25.729  -8.844  74.445  1.00 54.30  ? 176 VAL B CG1 1 
ATOM   5172  C CG2 . VAL B 1 116 ? -26.068  -11.293 73.984  1.00 59.59  ? 176 VAL B CG2 1 
ATOM   5173  N N   . VAL B 1 117 ? -27.166  -9.780  77.318  1.00 55.48  ? 177 VAL B N   1 
ATOM   5174  C CA  . VAL B 1 117 ? -26.708  -10.285 78.645  1.00 53.04  ? 177 VAL B CA  1 
ATOM   5175  C C   . VAL B 1 117 ? -27.933  -10.755 79.433  1.00 60.21  ? 177 VAL B C   1 
ATOM   5176  O O   . VAL B 1 117 ? -27.825  -11.827 80.105  1.00 62.80  ? 177 VAL B O   1 
ATOM   5177  C CB  . VAL B 1 117 ? -25.921  -9.211  79.411  1.00 45.56  ? 177 VAL B CB  1 
ATOM   5178  C CG1 . VAL B 1 117 ? -25.680  -9.594  80.863  1.00 38.66  ? 177 VAL B CG1 1 
ATOM   5179  C CG2 . VAL B 1 117 ? -24.623  -8.877  78.711  1.00 47.26  ? 177 VAL B CG2 1 
ATOM   5180  N N   . GLU B 1 118 ? -29.033  -9.984  79.356  1.00 67.72  ? 178 GLU B N   1 
ATOM   5181  C CA  . GLU B 1 118 ? -30.294  -10.202 80.131  1.00 69.57  ? 178 GLU B CA  1 
ATOM   5182  C C   . GLU B 1 118 ? -31.050  -11.411 79.562  1.00 64.94  ? 178 GLU B C   1 
ATOM   5183  O O   . GLU B 1 118 ? -31.608  -12.169 80.373  1.00 71.06  ? 178 GLU B O   1 
ATOM   5184  C CB  . GLU B 1 118 ? -31.194  -8.958  80.147  1.00 63.64  ? 178 GLU B CB  1 
ATOM   5185  C CG  . GLU B 1 118 ? -32.434  -9.164  81.005  1.00 67.47  ? 178 GLU B CG  1 
ATOM   5186  C CD  . GLU B 1 118 ? -33.338  -7.960  81.225  1.00 69.44  ? 178 GLU B CD  1 
ATOM   5187  O OE1 . GLU B 1 118 ? -32.935  -6.859  80.861  1.00 71.13  ? 178 GLU B OE1 1 
ATOM   5188  O OE2 . GLU B 1 118 ? -34.438  -8.119  81.804  1.00 56.33  ? 178 GLU B OE2 1 
ATOM   5189  N N   . LEU B 1 119 ? -31.027  -11.591 78.235  1.00 60.10  ? 179 LEU B N   1 
ATOM   5190  C CA  . LEU B 1 119 ? -31.939  -12.498 77.488  1.00 60.80  ? 179 LEU B CA  1 
ATOM   5191  C C   . LEU B 1 119 ? -31.259  -13.827 77.175  1.00 51.51  ? 179 LEU B C   1 
ATOM   5192  O O   . LEU B 1 119 ? -31.967  -14.795 76.911  1.00 54.74  ? 179 LEU B O   1 
ATOM   5193  C CB  . LEU B 1 119 ? -32.367  -11.814 76.184  1.00 62.71  ? 179 LEU B CB  1 
ATOM   5194  C CG  . LEU B 1 119 ? -33.369  -10.665 76.314  1.00 59.23  ? 179 LEU B CG  1 
ATOM   5195  C CD1 . LEU B 1 119 ? -33.872  -10.231 74.932  1.00 61.54  ? 179 LEU B CD1 1 
ATOM   5196  C CD2 . LEU B 1 119 ? -34.533  -11.060 77.203  1.00 51.73  ? 179 LEU B CD2 1 
ATOM   5197  N N   . LEU B 1 120 ? -29.939  -13.869 77.174  1.00 53.02  ? 180 LEU B N   1 
ATOM   5198  C CA  . LEU B 1 120 ? -29.193  -15.053 76.680  1.00 55.84  ? 180 LEU B CA  1 
ATOM   5199  C C   . LEU B 1 120 ? -29.523  -16.295 77.519  1.00 53.29  ? 180 LEU B C   1 
ATOM   5200  O O   . LEU B 1 120 ? -29.580  -17.413 77.008  1.00 39.50  ? 180 LEU B O   1 
ATOM   5201  C CB  . LEU B 1 120 ? -27.698  -14.724 76.682  1.00 50.51  ? 180 LEU B CB  1 
ATOM   5202  C CG  . LEU B 1 120 ? -26.836  -15.727 75.931  1.00 53.42  ? 180 LEU B CG  1 
ATOM   5203  C CD1 . LEU B 1 120 ? -27.373  -15.945 74.538  1.00 54.11  ? 180 LEU B CD1 1 
ATOM   5204  C CD2 . LEU B 1 120 ? -25.381  -15.267 75.885  1.00 62.76  ? 180 LEU B CD2 1 
ATOM   5205  N N   . PRO B 1 121 ? -29.712  -16.157 78.850  1.00 51.95  ? 181 PRO B N   1 
ATOM   5206  C CA  . PRO B 1 121 ? -30.015  -17.327 79.676  1.00 53.02  ? 181 PRO B CA  1 
ATOM   5207  C C   . PRO B 1 121 ? -31.406  -17.931 79.382  1.00 49.30  ? 181 PRO B C   1 
ATOM   5208  O O   . PRO B 1 121 ? -31.666  -19.048 79.794  1.00 52.54  ? 181 PRO B O   1 
ATOM   5209  C CB  . PRO B 1 121 ? -29.882  -16.805 81.126  1.00 48.54  ? 181 PRO B CB  1 
ATOM   5210  C CG  . PRO B 1 121 ? -29.209  -15.433 81.016  1.00 44.03  ? 181 PRO B CG  1 
ATOM   5211  C CD  . PRO B 1 121 ? -29.553  -14.920 79.639  1.00 45.86  ? 181 PRO B CD  1 
ATOM   5212  N N   . PHE B 1 122 ? -32.265  -17.188 78.686  1.00 43.99  ? 182 PHE B N   1 
ATOM   5213  C CA  . PHE B 1 122 ? -33.678  -17.561 78.403  1.00 48.43  ? 182 PHE B CA  1 
ATOM   5214  C C   . PHE B 1 122 ? -33.785  -18.259 77.042  1.00 52.46  ? 182 PHE B C   1 
ATOM   5215  O O   . PHE B 1 122 ? -34.476  -19.281 76.998  1.00 63.35  ? 182 PHE B O   1 
ATOM   5216  C CB  . PHE B 1 122 ? -34.585  -16.331 78.501  1.00 52.13  ? 182 PHE B CB  1 
ATOM   5217  C CG  . PHE B 1 122 ? -34.597  -15.704 79.870  1.00 53.63  ? 182 PHE B CG  1 
ATOM   5218  C CD1 . PHE B 1 122 ? -34.873  -16.478 80.989  1.00 54.21  ? 182 PHE B CD1 1 
ATOM   5219  C CD2 . PHE B 1 122 ? -34.341  -14.352 80.049  1.00 52.70  ? 182 PHE B CD2 1 
ATOM   5220  C CE1 . PHE B 1 122 ? -34.893  -15.908 82.255  1.00 57.50  ? 182 PHE B CE1 1 
ATOM   5221  C CE2 . PHE B 1 122 ? -34.356  -13.786 81.315  1.00 50.86  ? 182 PHE B CE2 1 
ATOM   5222  C CZ  . PHE B 1 122 ? -34.639  -14.559 82.412  1.00 55.63  ? 182 PHE B CZ  1 
ATOM   5223  N N   . VAL B 1 123 ? -33.084  -17.778 76.003  1.00 51.03  ? 183 VAL B N   1 
ATOM   5224  C CA  . VAL B 1 123 ? -33.060  -18.387 74.635  1.00 49.04  ? 183 VAL B CA  1 
ATOM   5225  C C   . VAL B 1 123 ? -32.013  -19.511 74.540  1.00 50.32  ? 183 VAL B C   1 
ATOM   5226  O O   . VAL B 1 123 ? -32.163  -20.379 73.671  1.00 52.24  ? 183 VAL B O   1 
ATOM   5227  C CB  . VAL B 1 123 ? -32.833  -17.302 73.571  1.00 51.79  ? 183 VAL B CB  1 
ATOM   5228  C CG1 . VAL B 1 123 ? -33.969  -16.297 73.562  1.00 56.14  ? 183 VAL B CG1 1 
ATOM   5229  C CG2 . VAL B 1 123 ? -31.521  -16.563 73.747  1.00 54.03  ? 183 VAL B CG2 1 
ATOM   5230  N N   . TYR B 1 124 ? -30.969  -19.456 75.376  1.00 63.82  ? 184 TYR B N   1 
ATOM   5231  C CA  . TYR B 1 124 ? -29.766  -20.344 75.416  1.00 56.66  ? 184 TYR B CA  1 
ATOM   5232  C C   . TYR B 1 124 ? -29.655  -20.961 76.813  1.00 50.25  ? 184 TYR B C   1 
ATOM   5233  O O   . TYR B 1 124 ? -30.639  -20.837 77.590  1.00 50.58  ? 184 TYR B O   1 
ATOM   5234  C CB  . TYR B 1 124 ? -28.503  -19.539 75.069  1.00 58.82  ? 184 TYR B CB  1 
ATOM   5235  C CG  . TYR B 1 124 ? -27.316  -20.345 74.605  1.00 59.87  ? 184 TYR B CG  1 
ATOM   5236  C CD1 . TYR B 1 124 ? -27.490  -21.480 73.823  1.00 60.70  ? 184 TYR B CD1 1 
ATOM   5237  C CD2 . TYR B 1 124 ? -26.025  -19.973 74.932  1.00 53.33  ? 184 TYR B CD2 1 
ATOM   5238  C CE1 . TYR B 1 124 ? -26.422  -22.236 73.380  1.00 54.99  ? 184 TYR B CE1 1 
ATOM   5239  C CE2 . TYR B 1 124 ? -24.948  -20.733 74.518  1.00 57.24  ? 184 TYR B CE2 1 
ATOM   5240  C CZ  . TYR B 1 124 ? -25.146  -21.861 73.736  1.00 57.94  ? 184 TYR B CZ  1 
ATOM   5241  O OH  . TYR B 1 124 ? -24.099  -22.616 73.305  1.00 67.06  ? 184 TYR B OH  1 
ATOM   5242  N N   . THR B 1 125 ? -28.528  -21.608 77.142  1.00 50.26  ? 185 THR B N   1 
ATOM   5243  C CA  . THR B 1 125 ? -28.323  -22.242 78.482  1.00 53.41  ? 185 THR B CA  1 
ATOM   5244  C C   . THR B 1 125 ? -28.512  -21.187 79.578  1.00 49.81  ? 185 THR B C   1 
ATOM   5245  O O   . THR B 1 125 ? -27.967  -20.083 79.481  1.00 45.76  ? 185 THR B O   1 
ATOM   5246  C CB  . THR B 1 125 ? -26.973  -22.962 78.585  1.00 54.76  ? 185 THR B CB  1 
ATOM   5247  O OG1 . THR B 1 125 ? -26.840  -23.640 79.839  1.00 57.41  ? 185 THR B OG1 1 
ATOM   5248  C CG2 . THR B 1 125 ? -25.799  -22.020 78.451  1.00 65.49  ? 185 THR B CG2 1 
ATOM   5249  N N   . PRO B 1 126 ? -29.279  -21.491 80.658  1.00 49.09  ? 186 PRO B N   1 
ATOM   5250  C CA  . PRO B 1 126 ? -29.831  -22.839 80.929  1.00 49.59  ? 186 PRO B CA  1 
ATOM   5251  C C   . PRO B 1 126 ? -31.288  -23.182 80.544  1.00 50.98  ? 186 PRO B C   1 
ATOM   5252  O O   . PRO B 1 126 ? -31.673  -24.383 80.529  1.00 59.08  ? 186 PRO B O   1 
ATOM   5253  C CB  . PRO B 1 126 ? -29.781  -22.863 82.451  1.00 47.53  ? 186 PRO B CB  1 
ATOM   5254  C CG  . PRO B 1 126 ? -30.200  -21.447 82.798  1.00 53.94  ? 186 PRO B CG  1 
ATOM   5255  C CD  . PRO B 1 126 ? -29.573  -20.545 81.738  1.00 49.68  ? 186 PRO B CD  1 
ATOM   5256  N N   . THR B 1 127 ? -32.085  -22.162 80.231  1.00 50.38  ? 187 THR B N   1 
ATOM   5257  C CA  . THR B 1 127 ? -33.530  -22.283 79.918  1.00 51.85  ? 187 THR B CA  1 
ATOM   5258  C C   . THR B 1 127 ? -33.745  -23.294 78.788  1.00 45.38  ? 187 THR B C   1 
ATOM   5259  O O   . THR B 1 127 ? -34.692  -24.086 78.860  1.00 41.38  ? 187 THR B O   1 
ATOM   5260  C CB  . THR B 1 127 ? -34.102  -20.917 79.539  1.00 52.59  ? 187 THR B CB  1 
ATOM   5261  O OG1 . THR B 1 127 ? -33.867  -20.029 80.634  1.00 55.59  ? 187 THR B OG1 1 
ATOM   5262  C CG2 . THR B 1 127 ? -35.577  -20.998 79.237  1.00 50.51  ? 187 THR B CG2 1 
ATOM   5263  N N   . VAL B 1 128 ? -32.899  -23.218 77.771  1.00 49.15  ? 188 VAL B N   1 
ATOM   5264  C CA  . VAL B 1 128 ? -33.026  -23.968 76.486  1.00 56.33  ? 188 VAL B CA  1 
ATOM   5265  C C   . VAL B 1 128 ? -32.992  -25.474 76.801  1.00 57.57  ? 188 VAL B C   1 
ATOM   5266  O O   . VAL B 1 128 ? -33.367  -26.303 75.931  1.00 55.22  ? 188 VAL B O   1 
ATOM   5267  C CB  . VAL B 1 128 ? -31.911  -23.545 75.513  1.00 56.88  ? 188 VAL B CB  1 
ATOM   5268  C CG1 . VAL B 1 128 ? -30.548  -24.069 75.974  1.00 58.26  ? 188 VAL B CG1 1 
ATOM   5269  C CG2 . VAL B 1 128 ? -32.215  -23.963 74.087  1.00 59.23  ? 188 VAL B CG2 1 
ATOM   5270  N N   . GLY B 1 129 ? -32.518  -25.820 77.990  1.00 53.68  ? 189 GLY B N   1 
ATOM   5271  C CA  . GLY B 1 129 ? -32.464  -27.214 78.440  1.00 56.19  ? 189 GLY B CA  1 
ATOM   5272  C C   . GLY B 1 129 ? -33.838  -27.683 78.827  1.00 55.44  ? 189 GLY B C   1 
ATOM   5273  O O   . GLY B 1 129 ? -34.244  -28.720 78.338  1.00 64.55  ? 189 GLY B O   1 
ATOM   5274  N N   . GLU B 1 130 ? -34.507  -26.937 79.704  1.00 60.41  ? 190 GLU B N   1 
ATOM   5275  C CA  . GLU B 1 130 ? -35.907  -27.181 80.139  1.00 55.78  ? 190 GLU B CA  1 
ATOM   5276  C C   . GLU B 1 130 ? -36.793  -27.206 78.878  1.00 64.00  ? 190 GLU B C   1 
ATOM   5277  O O   . GLU B 1 130 ? -37.606  -28.164 78.730  1.00 54.21  ? 190 GLU B O   1 
ATOM   5278  C CB  . GLU B 1 130 ? -36.326  -26.086 81.127  1.00 56.23  ? 190 GLU B CB  1 
ATOM   5279  C CG  . GLU B 1 130 ? -37.798  -26.139 81.483  1.00 70.79  ? 190 GLU B CG  1 
ATOM   5280  C CD  . GLU B 1 130 ? -38.266  -25.294 82.654  1.00 79.37  ? 190 GLU B CD  1 
ATOM   5281  O OE1 . GLU B 1 130 ? -38.013  -24.064 82.658  1.00 102.50 ? 190 GLU B OE1 1 
ATOM   5282  O OE2 . GLU B 1 130 ? -38.930  -25.866 83.537  1.00 80.43  ? 190 GLU B OE2 1 
ATOM   5283  N N   . ALA B 1 131 ? -36.629  -26.212 77.979  1.00 56.72  ? 191 ALA B N   1 
ATOM   5284  C CA  . ALA B 1 131 ? -37.388  -26.123 76.715  1.00 44.85  ? 191 ALA B CA  1 
ATOM   5285  C C   . ALA B 1 131 ? -37.291  -27.487 76.028  1.00 41.84  ? 191 ALA B C   1 
ATOM   5286  O O   . ALA B 1 131 ? -38.308  -27.956 75.568  1.00 51.55  ? 191 ALA B O   1 
ATOM   5287  C CB  . ALA B 1 131 ? -36.914  -24.995 75.821  1.00 38.69  ? 191 ALA B CB  1 
ATOM   5288  N N   . CYS B 1 132 ? -36.124  -28.118 75.981  1.00 39.30  ? 192 CYS B N   1 
ATOM   5289  C CA  . CYS B 1 132 ? -35.934  -29.413 75.262  1.00 44.74  ? 192 CYS B CA  1 
ATOM   5290  C C   . CYS B 1 132 ? -36.599  -30.559 76.031  1.00 47.37  ? 192 CYS B C   1 
ATOM   5291  O O   . CYS B 1 132 ? -37.039  -31.523 75.399  1.00 50.07  ? 192 CYS B O   1 
ATOM   5292  C CB  . CYS B 1 132 ? -34.471  -29.753 75.022  1.00 45.37  ? 192 CYS B CB  1 
ATOM   5293  S SG  . CYS B 1 132 ? -33.777  -28.804 73.651  1.00 51.24  ? 192 CYS B SG  1 
ATOM   5294  N N   . GLN B 1 133 ? -36.665  -30.472 77.348  1.00 51.26  ? 193 GLN B N   1 
ATOM   5295  C CA  . GLN B 1 133 ? -37.228  -31.559 78.182  1.00 58.60  ? 193 GLN B CA  1 
ATOM   5296  C C   . GLN B 1 133 ? -38.740  -31.577 78.008  1.00 56.44  ? 193 GLN B C   1 
ATOM   5297  O O   . GLN B 1 133 ? -39.327  -32.689 78.061  1.00 58.87  ? 193 GLN B O   1 
ATOM   5298  C CB  . GLN B 1 133 ? -36.826  -31.362 79.643  1.00 63.20  ? 193 GLN B CB  1 
ATOM   5299  C CG  . GLN B 1 133 ? -35.393  -31.777 79.904  1.00 62.35  ? 193 GLN B CG  1 
ATOM   5300  C CD  . GLN B 1 133 ? -34.961  -31.473 81.303  1.00 60.78  ? 193 GLN B CD  1 
ATOM   5301  O OE1 . GLN B 1 133 ? -35.072  -30.338 81.753  1.00 63.99  ? 193 GLN B OE1 1 
ATOM   5302  N NE2 . GLN B 1 133 ? -34.439  -32.492 81.959  1.00 55.01  ? 193 GLN B NE2 1 
ATOM   5303  N N   . LYS B 1 134 ? -39.320  -30.387 77.812  1.00 55.89  ? 194 LYS B N   1 
ATOM   5304  C CA  . LYS B 1 134 ? -40.790  -30.158 77.733  1.00 59.10  ? 194 LYS B CA  1 
ATOM   5305  C C   . LYS B 1 134 ? -41.178  -29.665 76.337  1.00 54.53  ? 194 LYS B C   1 
ATOM   5306  O O   . LYS B 1 134 ? -42.211  -28.988 76.248  1.00 61.03  ? 194 LYS B O   1 
ATOM   5307  C CB  . LYS B 1 134 ? -41.209  -29.127 78.788  1.00 65.72  ? 194 LYS B CB  1 
ATOM   5308  C CG  . LYS B 1 134 ? -40.992  -29.563 80.234  1.00 70.06  ? 194 LYS B CG  1 
ATOM   5309  C CD  . LYS B 1 134 ? -40.957  -28.437 81.238  1.00 70.19  ? 194 LYS B CD  1 
ATOM   5310  C CE  . LYS B 1 134 ? -40.705  -28.952 82.638  1.00 72.59  ? 194 LYS B CE  1 
ATOM   5311  N NZ  . LYS B 1 134 ? -40.891  -27.863 83.620  1.00 78.65  ? 194 LYS B NZ  1 
ATOM   5312  N N   . TYR B 1 135 ? -40.402  -29.982 75.292  1.00 48.46  ? 195 TYR B N   1 
ATOM   5313  C CA  . TYR B 1 135 ? -40.582  -29.398 73.938  1.00 52.79  ? 195 TYR B CA  1 
ATOM   5314  C C   . TYR B 1 135 ? -41.981  -29.751 73.415  1.00 56.63  ? 195 TYR B C   1 
ATOM   5315  O O   . TYR B 1 135 ? -42.683  -28.863 72.877  1.00 57.90  ? 195 TYR B O   1 
ATOM   5316  C CB  . TYR B 1 135 ? -39.504  -29.877 72.964  1.00 53.33  ? 195 TYR B CB  1 
ATOM   5317  C CG  . TYR B 1 135 ? -39.140  -28.865 71.891  1.00 62.09  ? 195 TYR B CG  1 
ATOM   5318  C CD1 . TYR B 1 135 ? -38.612  -27.607 72.218  1.00 60.23  ? 195 TYR B CD1 1 
ATOM   5319  C CD2 . TYR B 1 135 ? -39.305  -29.172 70.546  1.00 54.95  ? 195 TYR B CD2 1 
ATOM   5320  C CE1 . TYR B 1 135 ? -38.233  -26.700 71.245  1.00 57.68  ? 195 TYR B CE1 1 
ATOM   5321  C CE2 . TYR B 1 135 ? -38.974  -28.255 69.563  1.00 60.24  ? 195 TYR B CE2 1 
ATOM   5322  C CZ  . TYR B 1 135 ? -38.421  -27.028 69.911  1.00 62.80  ? 195 TYR B CZ  1 
ATOM   5323  O OH  . TYR B 1 135 ? -38.034  -26.159 68.927  1.00 58.07  ? 195 TYR B OH  1 
ATOM   5324  N N   . GLY B 1 136 ? -42.371  -31.012 73.600  1.00 52.32  ? 196 GLY B N   1 
ATOM   5325  C CA  . GLY B 1 136 ? -43.627  -31.562 73.084  1.00 49.63  ? 196 GLY B CA  1 
ATOM   5326  C C   . GLY B 1 136 ? -44.837  -30.859 73.662  1.00 50.83  ? 196 GLY B C   1 
ATOM   5327  O O   . GLY B 1 136 ? -45.823  -30.734 72.936  1.00 60.25  ? 196 GLY B O   1 
ATOM   5328  N N   . SER B 1 137 ? -44.785  -30.434 74.921  1.00 50.89  ? 197 SER B N   1 
ATOM   5329  C CA  . SER B 1 137 ? -45.938  -29.845 75.655  1.00 59.56  ? 197 SER B CA  1 
ATOM   5330  C C   . SER B 1 137 ? -45.993  -28.312 75.481  1.00 58.80  ? 197 SER B C   1 
ATOM   5331  O O   . SER B 1 137 ? -46.983  -27.720 75.914  1.00 63.39  ? 197 SER B O   1 
ATOM   5332  C CB  . SER B 1 137 ? -45.894  -30.246 77.101  1.00 54.69  ? 197 SER B CB  1 
ATOM   5333  O OG  . SER B 1 137 ? -44.866  -29.528 77.761  1.00 51.99  ? 197 SER B OG  1 
ATOM   5334  N N   . ILE B 1 138 ? -44.991  -27.711 74.840  1.00 65.18  ? 198 ILE B N   1 
ATOM   5335  C CA  . ILE B 1 138 ? -44.837  -26.233 74.722  1.00 76.71  ? 198 ILE B CA  1 
ATOM   5336  C C   . ILE B 1 138 ? -45.532  -25.815 73.430  1.00 87.23  ? 198 ILE B C   1 
ATOM   5337  O O   . ILE B 1 138 ? -45.470  -26.591 72.439  1.00 85.50  ? 198 ILE B O   1 
ATOM   5338  C CB  . ILE B 1 138 ? -43.347  -25.797 74.757  1.00 87.23  ? 198 ILE B CB  1 
ATOM   5339  C CG1 . ILE B 1 138 ? -42.723  -25.882 76.153  1.00 76.81  ? 198 ILE B CG1 1 
ATOM   5340  C CG2 . ILE B 1 138 ? -43.155  -24.402 74.178  1.00 99.94  ? 198 ILE B CG2 1 
ATOM   5341  C CD1 . ILE B 1 138 ? -43.678  -25.570 77.285  1.00 78.71  ? 198 ILE B CD1 1 
ATOM   5342  N N   . PHE B 1 139 ? -46.181  -24.643 73.460  1.00 105.99 ? 199 PHE B N   1 
ATOM   5343  C CA  . PHE B 1 139 ? -46.843  -24.013 72.285  1.00 111.97 ? 199 PHE B CA  1 
ATOM   5344  C C   . PHE B 1 139 ? -45.781  -23.772 71.210  1.00 104.24 ? 199 PHE B C   1 
ATOM   5345  O O   . PHE B 1 139 ? -44.816  -23.044 71.464  1.00 91.34  ? 199 PHE B O   1 
ATOM   5346  C CB  . PHE B 1 139 ? -47.608  -22.743 72.676  1.00 116.16 ? 199 PHE B CB  1 
ATOM   5347  C CG  . PHE B 1 139 ? -48.137  -21.957 71.503  1.00 127.21 ? 199 PHE B CG  1 
ATOM   5348  C CD1 . PHE B 1 139 ? -47.429  -20.867 71.012  1.00 132.22 ? 199 PHE B CD1 1 
ATOM   5349  C CD2 . PHE B 1 139 ? -49.351  -22.283 70.904  1.00 116.05 ? 199 PHE B CD2 1 
ATOM   5350  C CE1 . PHE B 1 139 ? -47.904  -20.147 69.925  1.00 123.08 ? 199 PHE B CE1 1 
ATOM   5351  C CE2 . PHE B 1 139 ? -49.831  -21.547 69.831  1.00 117.19 ? 199 PHE B CE2 1 
ATOM   5352  C CZ  . PHE B 1 139 ? -49.108  -20.479 69.346  1.00 124.20 ? 199 PHE B CZ  1 
ATOM   5353  N N   . ARG B 1 140 ? -45.988  -24.380 70.043  1.00 103.32 ? 200 ARG B N   1 
ATOM   5354  C CA  . ARG B 1 140 ? -44.968  -24.579 68.988  1.00 107.49 ? 200 ARG B CA  1 
ATOM   5355  C C   . ARG B 1 140 ? -45.451  -23.875 67.716  1.00 100.81 ? 200 ARG B C   1 
ATOM   5356  O O   . ARG B 1 140 ? -46.382  -24.407 67.079  1.00 110.27 ? 200 ARG B O   1 
ATOM   5357  C CB  . ARG B 1 140 ? -44.725  -26.088 68.766  1.00 130.93 ? 200 ARG B CB  1 
ATOM   5358  C CG  . ARG B 1 140 ? -45.800  -26.878 68.006  1.00 125.24 ? 200 ARG B CG  1 
ATOM   5359  C CD  . ARG B 1 140 ? -47.126  -27.138 68.740  1.00 115.30 ? 200 ARG B CD  1 
ATOM   5360  N NE  . ARG B 1 140 ? -48.262  -27.523 67.869  1.00 97.18  ? 200 ARG B NE  1 
ATOM   5361  C CZ  . ARG B 1 140 ? -49.305  -28.323 68.167  1.00 57.27  ? 200 ARG B CZ  1 
ATOM   5362  N NH1 . ARG B 1 140 ? -50.248  -28.542 67.288  1.00 49.56  ? 200 ARG B NH1 1 
ATOM   5363  N NH2 . ARG B 1 140 ? -49.424  -28.928 69.313  1.00 53.14  ? 200 ARG B NH2 1 
ATOM   5364  N N   . ARG B 1 141 ? -44.869  -22.727 67.359  1.00 95.17  ? 201 ARG B N   1 
ATOM   5365  C CA  . ARG B 1 141 ? -44.833  -22.268 65.934  1.00 91.39  ? 201 ARG B CA  1 
ATOM   5366  C C   . ARG B 1 141 ? -43.668  -23.047 65.319  1.00 96.81  ? 201 ARG B C   1 
ATOM   5367  O O   . ARG B 1 141 ? -42.595  -23.037 65.909  1.00 110.76 ? 201 ARG B O   1 
ATOM   5368  C CB  . ARG B 1 141 ? -44.729  -20.736 65.797  1.00 84.68  ? 201 ARG B CB  1 
ATOM   5369  C CG  . ARG B 1 141 ? -45.712  -19.934 66.641  1.00 87.77  ? 201 ARG B CG  1 
ATOM   5370  C CD  . ARG B 1 141 ? -46.179  -18.594 66.091  1.00 86.48  ? 201 ARG B CD  1 
ATOM   5371  N NE  . ARG B 1 141 ? -47.024  -18.778 64.918  1.00 100.59 ? 201 ARG B NE  1 
ATOM   5372  C CZ  . ARG B 1 141 ? -47.863  -17.869 64.401  1.00 98.96  ? 201 ARG B CZ  1 
ATOM   5373  N NH1 . ARG B 1 141 ? -48.014  -16.663 64.955  1.00 90.74  ? 201 ARG B NH1 1 
ATOM   5374  N NH2 . ARG B 1 141 ? -48.563  -18.204 63.323  1.00 81.82  ? 201 ARG B NH2 1 
ATOM   5375  N N   . PRO B 1 142 ? -43.825  -23.816 64.205  1.00 97.07  ? 202 PRO B N   1 
ATOM   5376  C CA  . PRO B 1 142 ? -42.730  -24.638 63.674  1.00 83.68  ? 202 PRO B CA  1 
ATOM   5377  C C   . PRO B 1 142 ? -41.479  -23.849 63.213  1.00 79.72  ? 202 PRO B C   1 
ATOM   5378  O O   . PRO B 1 142 ? -41.559  -22.766 62.608  1.00 78.23  ? 202 PRO B O   1 
ATOM   5379  C CB  . PRO B 1 142 ? -43.363  -25.436 62.517  1.00 88.37  ? 202 PRO B CB  1 
ATOM   5380  C CG  . PRO B 1 142 ? -44.633  -24.672 62.153  1.00 99.52  ? 202 PRO B CG  1 
ATOM   5381  C CD  . PRO B 1 142 ? -45.058  -23.944 63.412  1.00 104.36 ? 202 PRO B CD  1 
ATOM   5382  N N   . GLN B 1 143 ? -40.317  -24.407 63.555  1.00 76.18  ? 203 GLN B N   1 
ATOM   5383  C CA  . GLN B 1 143 ? -38.956  -23.899 63.231  1.00 67.47  ? 203 GLN B CA  1 
ATOM   5384  C C   . GLN B 1 143 ? -38.032  -25.122 63.086  1.00 56.97  ? 203 GLN B C   1 
ATOM   5385  O O   . GLN B 1 143 ? -38.187  -26.166 63.794  1.00 56.89  ? 203 GLN B O   1 
ATOM   5386  C CB  . GLN B 1 143 ? -38.438  -22.891 64.268  1.00 65.44  ? 203 GLN B CB  1 
ATOM   5387  C CG  . GLN B 1 143 ? -39.037  -23.074 65.649  1.00 68.42  ? 203 GLN B CG  1 
ATOM   5388  C CD  . GLN B 1 143 ? -38.689  -21.959 66.597  1.00 71.04  ? 203 GLN B CD  1 
ATOM   5389  O OE1 . GLN B 1 143 ? -38.399  -20.831 66.193  1.00 75.09  ? 203 GLN B OE1 1 
ATOM   5390  N NE2 . GLN B 1 143 ? -38.703  -22.298 67.878  1.00 58.83  ? 203 GLN B NE2 1 
ATOM   5391  N N   . GLY B 1 144 ? -37.136  -25.031 62.131  1.00 49.59  ? 204 GLY B N   1 
ATOM   5392  C CA  . GLY B 1 144 ? -36.214  -26.119 61.782  1.00 58.45  ? 204 GLY B CA  1 
ATOM   5393  C C   . GLY B 1 144 ? -36.862  -27.267 61.037  1.00 53.68  ? 204 GLY B C   1 
ATOM   5394  O O   . GLY B 1 144 ? -38.093  -27.303 60.901  1.00 57.36  ? 204 GLY B O   1 
ATOM   5395  N N   . LEU B 1 145 ? -36.023  -28.200 60.606  1.00 43.44  ? 205 LEU B N   1 
ATOM   5396  C CA  . LEU B 1 145 ? -36.412  -29.322 59.728  1.00 54.38  ? 205 LEU B CA  1 
ATOM   5397  C C   . LEU B 1 145 ? -36.166  -30.640 60.461  1.00 45.09  ? 205 LEU B C   1 
ATOM   5398  O O   . LEU B 1 145 ? -35.073  -30.789 60.998  1.00 56.85  ? 205 LEU B O   1 
ATOM   5399  C CB  . LEU B 1 145 ? -35.548  -29.239 58.465  1.00 62.80  ? 205 LEU B CB  1 
ATOM   5400  C CG  . LEU B 1 145 ? -36.252  -29.022 57.126  1.00 66.37  ? 205 LEU B CG  1 
ATOM   5401  C CD1 . LEU B 1 145 ? -35.257  -29.083 56.003  1.00 59.69  ? 205 LEU B CD1 1 
ATOM   5402  C CD2 . LEU B 1 145 ? -37.353  -30.036 56.878  1.00 78.87  ? 205 LEU B CD2 1 
ATOM   5403  N N   . TYR B 1 146 ? -37.109  -31.571 60.448  1.00 40.38  ? 206 TYR B N   1 
ATOM   5404  C CA  . TYR B 1 146 ? -36.939  -32.902 61.089  1.00 46.53  ? 206 TYR B CA  1 
ATOM   5405  C C   . TYR B 1 146 ? -36.791  -33.955 59.989  1.00 47.33  ? 206 TYR B C   1 
ATOM   5406  O O   . TYR B 1 146 ? -37.714  -34.121 59.152  1.00 51.73  ? 206 TYR B O   1 
ATOM   5407  C CB  . TYR B 1 146 ? -38.085  -33.258 62.044  1.00 45.90  ? 206 TYR B CB  1 
ATOM   5408  C CG  . TYR B 1 146 ? -38.400  -32.228 63.097  1.00 51.24  ? 206 TYR B CG  1 
ATOM   5409  C CD1 . TYR B 1 146 ? -38.956  -30.994 62.747  1.00 59.06  ? 206 TYR B CD1 1 
ATOM   5410  C CD2 . TYR B 1 146 ? -38.165  -32.468 64.441  1.00 52.46  ? 206 TYR B CD2 1 
ATOM   5411  C CE1 . TYR B 1 146 ? -39.252  -30.019 63.686  1.00 48.42  ? 206 TYR B CE1 1 
ATOM   5412  C CE2 . TYR B 1 146 ? -38.467  -31.509 65.401  1.00 51.63  ? 206 TYR B CE2 1 
ATOM   5413  C CZ  . TYR B 1 146 ? -39.022  -30.296 65.017  1.00 50.17  ? 206 TYR B CZ  1 
ATOM   5414  O OH  . TYR B 1 146 ? -39.345  -29.326 65.913  1.00 56.83  ? 206 TYR B OH  1 
ATOM   5415  N N   . VAL B 1 147 ? -35.665  -34.658 60.003  1.00 44.14  ? 207 VAL B N   1 
ATOM   5416  C CA  . VAL B 1 147 ? -35.435  -35.844 59.131  1.00 49.71  ? 207 VAL B CA  1 
ATOM   5417  C C   . VAL B 1 147 ? -35.560  -37.109 59.969  1.00 46.33  ? 207 VAL B C   1 
ATOM   5418  O O   . VAL B 1 147 ? -34.692  -37.353 60.793  1.00 49.36  ? 207 VAL B O   1 
ATOM   5419  C CB  . VAL B 1 147 ? -34.064  -35.789 58.441  1.00 56.20  ? 207 VAL B CB  1 
ATOM   5420  C CG1 . VAL B 1 147 ? -33.834  -37.022 57.578  1.00 59.75  ? 207 VAL B CG1 1 
ATOM   5421  C CG2 . VAL B 1 147 ? -33.905  -34.508 57.644  1.00 58.21  ? 207 VAL B CG2 1 
ATOM   5422  N N   . SER B 1 148 ? -36.617  -37.884 59.784  1.00 54.16  ? 208 SER B N   1 
ATOM   5423  C CA  . SER B 1 148 ? -36.859  -39.113 60.583  1.00 54.48  ? 208 SER B CA  1 
ATOM   5424  C C   . SER B 1 148 ? -36.277  -40.308 59.849  1.00 53.28  ? 208 SER B C   1 
ATOM   5425  O O   . SER B 1 148 ? -35.818  -40.149 58.710  1.00 49.59  ? 208 SER B O   1 
ATOM   5426  C CB  . SER B 1 148 ? -38.308  -39.332 60.897  1.00 54.59  ? 208 SER B CB  1 
ATOM   5427  O OG  . SER B 1 148 ? -39.016  -39.737 59.744  1.00 59.77  ? 208 SER B OG  1 
ATOM   5428  N N   . LEU B 1 149 ? -36.289  -41.452 60.520  1.00 58.14  ? 209 LEU B N   1 
ATOM   5429  C CA  . LEU B 1 149 ? -35.948  -42.773 59.937  1.00 60.22  ? 209 LEU B CA  1 
ATOM   5430  C C   . LEU B 1 149 ? -36.944  -43.120 58.838  1.00 60.55  ? 209 LEU B C   1 
ATOM   5431  O O   . LEU B 1 149 ? -36.625  -43.953 58.006  1.00 71.61  ? 209 LEU B O   1 
ATOM   5432  C CB  . LEU B 1 149 ? -36.003  -43.838 61.028  1.00 67.52  ? 209 LEU B CB  1 
ATOM   5433  C CG  . LEU B 1 149 ? -34.649  -44.296 61.557  1.00 63.93  ? 209 LEU B CG  1 
ATOM   5434  C CD1 . LEU B 1 149 ? -34.828  -45.092 62.840  1.00 71.57  ? 209 LEU B CD1 1 
ATOM   5435  C CD2 . LEU B 1 149 ? -33.921  -45.111 60.511  1.00 61.91  ? 209 LEU B CD2 1 
ATOM   5436  N N   . LYS B 1 150 ? -38.121  -42.515 58.845  1.00 65.63  ? 210 LYS B N   1 
ATOM   5437  C CA  . LYS B 1 150 ? -39.167  -42.791 57.830  1.00 71.10  ? 210 LYS B CA  1 
ATOM   5438  C C   . LYS B 1 150 ? -38.995  -41.855 56.633  1.00 74.15  ? 210 LYS B C   1 
ATOM   5439  O O   . LYS B 1 150 ? -39.876  -41.883 55.788  1.00 83.37  ? 210 LYS B O   1 
ATOM   5440  C CB  . LYS B 1 150 ? -40.554  -42.701 58.485  1.00 73.74  ? 210 LYS B CB  1 
ATOM   5441  C CG  . LYS B 1 150 ? -40.956  -43.931 59.312  1.00 83.68  ? 210 LYS B CG  1 
ATOM   5442  C CD  . LYS B 1 150 ? -41.425  -45.177 58.508  1.00 92.69  ? 210 LYS B CD  1 
ATOM   5443  C CE  . LYS B 1 150 ? -40.289  -46.093 58.053  1.00 95.84  ? 210 LYS B CE  1 
ATOM   5444  N NZ  . LYS B 1 150 ? -40.463  -46.571 56.655  1.00 89.58  ? 210 LYS B NZ  1 
ATOM   5445  N N   . ASP B 1 151 ? -37.909  -41.078 56.565  1.00 77.84  ? 211 ASP B N   1 
ATOM   5446  C CA  . ASP B 1 151 ? -37.598  -40.163 55.427  1.00 72.14  ? 211 ASP B CA  1 
ATOM   5447  C C   . ASP B 1 151 ? -36.405  -40.755 54.653  1.00 70.69  ? 211 ASP B C   1 
ATOM   5448  O O   . ASP B 1 151 ? -35.885  -40.092 53.713  1.00 80.57  ? 211 ASP B O   1 
ATOM   5449  C CB  . ASP B 1 151 ? -37.393  -38.719 55.919  1.00 69.66  ? 211 ASP B CB  1 
ATOM   5450  C CG  . ASP B 1 151 ? -38.576  -38.139 56.700  1.00 74.38  ? 211 ASP B CG  1 
ATOM   5451  O OD1 . ASP B 1 151 ? -39.710  -38.358 56.283  1.00 72.42  ? 211 ASP B OD1 1 
ATOM   5452  O OD2 . ASP B 1 151 ? -38.366  -37.487 57.745  1.00 78.53  ? 211 ASP B OD2 1 
ATOM   5453  N N   . LYS B 1 152 ? -35.988  -41.981 55.005  1.00 64.83  ? 212 LYS B N   1 
ATOM   5454  C CA  . LYS B 1 152 ? -34.805  -42.627 54.370  1.00 65.42  ? 212 LYS B CA  1 
ATOM   5455  C C   . LYS B 1 152 ? -35.208  -43.106 52.981  1.00 62.24  ? 212 LYS B C   1 
ATOM   5456  O O   . LYS B 1 152 ? -36.327  -43.563 52.831  1.00 69.55  ? 212 LYS B O   1 
ATOM   5457  C CB  . LYS B 1 152 ? -34.254  -43.751 55.241  1.00 63.31  ? 212 LYS B CB  1 
ATOM   5458  C CG  . LYS B 1 152 ? -33.789  -44.969 54.492  1.00 67.83  ? 212 LYS B CG  1 
ATOM   5459  C CD  . LYS B 1 152 ? -32.988  -45.884 55.376  1.00 86.03  ? 212 LYS B CD  1 
ATOM   5460  C CE  . LYS B 1 152 ? -33.227  -47.336 55.026  1.00 100.49 ? 212 LYS B CE  1 
ATOM   5461  N NZ  . LYS B 1 152 ? -34.651  -47.721 55.235  1.00 107.82 ? 212 LYS B NZ  1 
ATOM   5462  N N   . GLY B 1 153 ? -34.320  -42.977 52.008  1.00 65.08  ? 213 GLY B N   1 
ATOM   5463  C CA  . GLY B 1 153 ? -34.678  -43.043 50.582  1.00 66.63  ? 213 GLY B CA  1 
ATOM   5464  C C   . GLY B 1 153 ? -35.075  -41.675 50.054  1.00 72.25  ? 213 GLY B C   1 
ATOM   5465  O O   . GLY B 1 153 ? -34.858  -41.445 48.841  1.00 77.10  ? 213 GLY B O   1 
ATOM   5466  N N   . LYS B 1 154 ? -35.623  -40.789 50.897  1.00 72.65  ? 214 LYS B N   1 
ATOM   5467  C CA  . LYS B 1 154 ? -36.257  -39.531 50.415  1.00 77.27  ? 214 LYS B CA  1 
ATOM   5468  C C   . LYS B 1 154 ? -35.724  -38.316 51.171  1.00 70.63  ? 214 LYS B C   1 
ATOM   5469  O O   . LYS B 1 154 ? -36.420  -37.313 51.207  1.00 62.05  ? 214 LYS B O   1 
ATOM   5470  C CB  . LYS B 1 154 ? -37.786  -39.609 50.556  1.00 90.56  ? 214 LYS B CB  1 
ATOM   5471  C CG  . LYS B 1 154 ? -38.426  -40.914 50.103  1.00 101.44 ? 214 LYS B CG  1 
ATOM   5472  C CD  . LYS B 1 154 ? -39.821  -40.761 49.501  1.00 103.20 ? 214 LYS B CD  1 
ATOM   5473  C CE  . LYS B 1 154 ? -40.517  -42.094 49.353  1.00 109.11 ? 214 LYS B CE  1 
ATOM   5474  N NZ  . LYS B 1 154 ? -41.974  -41.925 49.132  1.00 109.07 ? 214 LYS B NZ  1 
ATOM   5475  N N   . VAL B 1 155 ? -34.541  -38.405 51.761  1.00 66.69  ? 215 VAL B N   1 
ATOM   5476  C CA  . VAL B 1 155 ? -34.001  -37.306 52.607  1.00 61.84  ? 215 VAL B CA  1 
ATOM   5477  C C   . VAL B 1 155 ? -33.879  -36.026 51.775  1.00 66.45  ? 215 VAL B C   1 
ATOM   5478  O O   . VAL B 1 155 ? -34.143  -34.937 52.285  1.00 62.18  ? 215 VAL B O   1 
ATOM   5479  C CB  . VAL B 1 155 ? -32.652  -37.697 53.214  1.00 61.82  ? 215 VAL B CB  1 
ATOM   5480  C CG1 . VAL B 1 155 ? -32.055  -36.495 53.932  1.00 66.95  ? 215 VAL B CG1 1 
ATOM   5481  C CG2 . VAL B 1 155 ? -32.787  -38.885 54.149  1.00 60.94  ? 215 VAL B CG2 1 
ATOM   5482  N N   . LEU B 1 156 ? -33.444  -36.154 50.531  1.00 75.30  ? 216 LEU B N   1 
ATOM   5483  C CA  . LEU B 1 156 ? -33.241  -34.985 49.638  1.00 70.34  ? 216 LEU B CA  1 
ATOM   5484  C C   . LEU B 1 156 ? -34.596  -34.344 49.371  1.00 62.73  ? 216 LEU B C   1 
ATOM   5485  O O   . LEU B 1 156 ? -34.648  -33.110 49.324  1.00 66.76  ? 216 LEU B O   1 
ATOM   5486  C CB  . LEU B 1 156 ? -32.569  -35.475 48.353  1.00 70.90  ? 216 LEU B CB  1 
ATOM   5487  C CG  . LEU B 1 156 ? -32.255  -34.431 47.282  1.00 70.48  ? 216 LEU B CG  1 
ATOM   5488  C CD1 . LEU B 1 156 ? -31.701  -33.119 47.849  1.00 66.85  ? 216 LEU B CD1 1 
ATOM   5489  C CD2 . LEU B 1 156 ? -31.305  -35.027 46.251  1.00 63.81  ? 216 LEU B CD2 1 
ATOM   5490  N N   . GLU B 1 157 ? -35.625  -35.171 49.167  1.00 63.93  ? 217 GLU B N   1 
ATOM   5491  C CA  . GLU B 1 157 ? -37.038  -34.735 48.960  1.00 70.44  ? 217 GLU B CA  1 
ATOM   5492  C C   . GLU B 1 157 ? -37.451  -33.840 50.139  1.00 68.04  ? 217 GLU B C   1 
ATOM   5493  O O   . GLU B 1 157 ? -38.126  -32.833 49.910  1.00 65.65  ? 217 GLU B O   1 
ATOM   5494  C CB  . GLU B 1 157 ? -37.928  -35.967 48.810  1.00 74.32  ? 217 GLU B CB  1 
ATOM   5495  C CG  . GLU B 1 157 ? -39.403  -35.727 49.053  1.00 79.55  ? 217 GLU B CG  1 
ATOM   5496  C CD  . GLU B 1 157 ? -40.325  -36.817 48.526  1.00 83.19  ? 217 GLU B CD  1 
ATOM   5497  O OE1 . GLU B 1 157 ? -40.053  -37.355 47.437  1.00 81.28  ? 217 GLU B OE1 1 
ATOM   5498  O OE2 . GLU B 1 157 ? -41.323  -37.100 49.197  1.00 82.62  ? 217 GLU B OE2 1 
ATOM   5499  N N   . VAL B 1 158 ? -37.057  -34.211 51.360  1.00 63.07  ? 218 VAL B N   1 
ATOM   5500  C CA  . VAL B 1 158 ? -37.384  -33.461 52.611  1.00 60.16  ? 218 VAL B CA  1 
ATOM   5501  C C   . VAL B 1 158 ? -36.617  -32.129 52.589  1.00 58.51  ? 218 VAL B C   1 
ATOM   5502  O O   . VAL B 1 158 ? -37.219  -31.095 52.891  1.00 69.59  ? 218 VAL B O   1 
ATOM   5503  C CB  . VAL B 1 158 ? -37.087  -34.283 53.886  1.00 59.55  ? 218 VAL B CB  1 
ATOM   5504  C CG1 . VAL B 1 158 ? -37.422  -33.520 55.165  1.00 57.56  ? 218 VAL B CG1 1 
ATOM   5505  C CG2 . VAL B 1 158 ? -37.796  -35.632 53.886  1.00 57.85  ? 218 VAL B CG2 1 
ATOM   5506  N N   . LEU B 1 159 ? -35.342  -32.141 52.220  1.00 51.02  ? 219 LEU B N   1 
ATOM   5507  C CA  . LEU B 1 159 ? -34.508  -30.917 52.136  1.00 49.99  ? 219 LEU B CA  1 
ATOM   5508  C C   . LEU B 1 159 ? -35.258  -29.905 51.244  1.00 55.17  ? 219 LEU B C   1 
ATOM   5509  O O   . LEU B 1 159 ? -35.284  -28.672 51.559  1.00 50.94  ? 219 LEU B O   1 
ATOM   5510  C CB  . LEU B 1 159 ? -33.135  -31.280 51.536  1.00 58.40  ? 219 LEU B CB  1 
ATOM   5511  C CG  . LEU B 1 159 ? -31.970  -31.665 52.450  1.00 54.47  ? 219 LEU B CG  1 
ATOM   5512  C CD1 . LEU B 1 159 ? -31.671  -30.532 53.390  1.00 52.95  ? 219 LEU B CD1 1 
ATOM   5513  C CD2 . LEU B 1 159 ? -32.236  -32.948 53.207  1.00 57.24  ? 219 LEU B CD2 1 
ATOM   5514  N N   . ARG B 1 160 ? -35.869  -30.412 50.171  1.00 58.46  ? 220 ARG B N   1 
ATOM   5515  C CA  . ARG B 1 160 ? -36.394  -29.575 49.074  1.00 73.13  ? 220 ARG B CA  1 
ATOM   5516  C C   . ARG B 1 160 ? -37.502  -28.685 49.642  1.00 70.22  ? 220 ARG B C   1 
ATOM   5517  O O   . ARG B 1 160 ? -37.713  -27.585 49.084  1.00 73.77  ? 220 ARG B O   1 
ATOM   5518  C CB  . ARG B 1 160 ? -36.837  -30.461 47.905  1.00 79.33  ? 220 ARG B CB  1 
ATOM   5519  C CG  . ARG B 1 160 ? -35.715  -30.692 46.912  1.00 96.15  ? 220 ARG B CG  1 
ATOM   5520  C CD  . ARG B 1 160 ? -36.021  -31.646 45.775  1.00 112.26 ? 220 ARG B CD  1 
ATOM   5521  N NE  . ARG B 1 160 ? -34.791  -32.220 45.230  1.00 134.50 ? 220 ARG B NE  1 
ATOM   5522  C CZ  . ARG B 1 160 ? -33.921  -31.606 44.399  1.00 127.58 ? 220 ARG B CZ  1 
ATOM   5523  N NH1 . ARG B 1 160 ? -34.128  -30.368 43.971  1.00 111.69 ? 220 ARG B NH1 1 
ATOM   5524  N NH2 . ARG B 1 160 ? -32.838  -32.249 43.987  1.00 128.68 ? 220 ARG B NH2 1 
ATOM   5525  N N   . ASN B 1 161 ? -38.161  -29.158 50.706  1.00 60.73  ? 221 ASN B N   1 
ATOM   5526  C CA  . ASN B 1 161 ? -39.337  -28.494 51.318  1.00 58.89  ? 221 ASN B CA  1 
ATOM   5527  C C   . ASN B 1 161 ? -38.913  -27.201 52.014  1.00 60.83  ? 221 ASN B C   1 
ATOM   5528  O O   . ASN B 1 161 ? -39.780  -26.331 52.185  1.00 62.85  ? 221 ASN B O   1 
ATOM   5529  C CB  . ASN B 1 161 ? -40.060  -29.415 52.298  1.00 57.52  ? 221 ASN B CB  1 
ATOM   5530  C CG  . ASN B 1 161 ? -40.979  -30.416 51.632  1.00 60.31  ? 221 ASN B CG  1 
ATOM   5531  O OD1 . ASN B 1 161 ? -41.310  -30.297 50.447  1.00 59.91  ? 221 ASN B OD1 1 
ATOM   5532  N ND2 . ASN B 1 161 ? -41.483  -31.354 52.420  1.00 63.66  ? 221 ASN B ND2 1 
ATOM   5533  N N   . TRP B 1 162 ? -37.650  -27.079 52.429  1.00 62.32  ? 222 TRP B N   1 
ATOM   5534  C CA  . TRP B 1 162 ? -37.191  -25.829 53.093  1.00 61.51  ? 222 TRP B CA  1 
ATOM   5535  C C   . TRP B 1 162 ? -37.218  -24.697 52.064  1.00 54.61  ? 222 TRP B C   1 
ATOM   5536  O O   . TRP B 1 162 ? -36.646  -24.823 50.991  1.00 53.67  ? 222 TRP B O   1 
ATOM   5537  C CB  . TRP B 1 162 ? -35.828  -26.022 53.781  1.00 58.49  ? 222 TRP B CB  1 
ATOM   5538  C CG  . TRP B 1 162 ? -35.446  -24.877 54.678  1.00 57.38  ? 222 TRP B CG  1 
ATOM   5539  C CD1 . TRP B 1 162 ? -34.656  -23.793 54.384  1.00 57.84  ? 222 TRP B CD1 1 
ATOM   5540  C CD2 . TRP B 1 162 ? -35.870  -24.692 56.036  1.00 50.70  ? 222 TRP B CD2 1 
ATOM   5541  N NE1 . TRP B 1 162 ? -34.561  -22.954 55.461  1.00 56.41  ? 222 TRP B NE1 1 
ATOM   5542  C CE2 . TRP B 1 162 ? -35.296  -23.479 56.489  1.00 55.33  ? 222 TRP B CE2 1 
ATOM   5543  C CE3 . TRP B 1 162 ? -36.654  -25.445 56.914  1.00 46.86  ? 222 TRP B CE3 1 
ATOM   5544  C CZ2 . TRP B 1 162 ? -35.493  -23.004 57.783  1.00 54.75  ? 222 TRP B CZ2 1 
ATOM   5545  C CZ3 . TRP B 1 162 ? -36.865  -24.966 58.188  1.00 49.20  ? 222 TRP B CZ3 1 
ATOM   5546  C CH2 . TRP B 1 162 ? -36.298  -23.755 58.606  1.00 54.82  ? 222 TRP B CH2 1 
ATOM   5547  N N   . PRO B 1 163 ? -37.884  -23.561 52.353  1.00 53.09  ? 223 PRO B N   1 
ATOM   5548  C CA  . PRO B 1 163 ? -38.135  -22.528 51.350  1.00 61.88  ? 223 PRO B CA  1 
ATOM   5549  C C   . PRO B 1 163 ? -37.030  -21.469 51.198  1.00 60.79  ? 223 PRO B C   1 
ATOM   5550  O O   . PRO B 1 163 ? -37.337  -20.345 50.818  1.00 62.50  ? 223 PRO B O   1 
ATOM   5551  C CB  . PRO B 1 163 ? -39.394  -21.868 51.932  1.00 63.98  ? 223 PRO B CB  1 
ATOM   5552  C CG  . PRO B 1 163 ? -39.120  -21.874 53.410  1.00 64.43  ? 223 PRO B CG  1 
ATOM   5553  C CD  . PRO B 1 163 ? -38.438  -23.206 53.660  1.00 58.43  ? 223 PRO B CD  1 
ATOM   5554  N N   . HIS B 1 164 ? -35.794  -21.818 51.568  1.00 65.03  ? 224 HIS B N   1 
ATOM   5555  C CA  . HIS B 1 164 ? -34.546  -21.047 51.310  1.00 59.32  ? 224 HIS B CA  1 
ATOM   5556  C C   . HIS B 1 164 ? -33.506  -22.007 50.699  1.00 66.00  ? 224 HIS B C   1 
ATOM   5557  O O   . HIS B 1 164 ? -33.252  -23.110 51.275  1.00 66.90  ? 224 HIS B O   1 
ATOM   5558  C CB  . HIS B 1 164 ? -34.046  -20.361 52.582  1.00 57.75  ? 224 HIS B CB  1 
ATOM   5559  C CG  . HIS B 1 164 ? -35.004  -19.439 53.262  1.00 66.13  ? 224 HIS B CG  1 
ATOM   5560  N ND1 . HIS B 1 164 ? -35.108  -18.096 52.928  1.00 69.80  ? 224 HIS B ND1 1 
ATOM   5561  C CD2 . HIS B 1 164 ? -35.899  -19.650 54.261  1.00 72.81  ? 224 HIS B CD2 1 
ATOM   5562  C CE1 . HIS B 1 164 ? -36.020  -17.510 53.689  1.00 70.18  ? 224 HIS B CE1 1 
ATOM   5563  N NE2 . HIS B 1 164 ? -36.542  -18.453 54.494  1.00 79.64  ? 224 HIS B NE2 1 
ATOM   5564  N N   . ARG B 1 165 ? -32.978  -21.664 49.525  1.00 74.01  ? 225 ARG B N   1 
ATOM   5565  C CA  . ARG B 1 165 ? -32.138  -22.564 48.675  1.00 89.43  ? 225 ARG B CA  1 
ATOM   5566  C C   . ARG B 1 165 ? -30.652  -22.337 49.013  1.00 86.13  ? 225 ARG B C   1 
ATOM   5567  O O   . ARG B 1 165 ? -29.889  -23.339 49.032  1.00 90.71  ? 225 ARG B O   1 
ATOM   5568  C CB  . ARG B 1 165 ? -32.447  -22.359 47.187  1.00 91.75  ? 225 ARG B CB  1 
ATOM   5569  C CG  . ARG B 1 165 ? -32.347  -20.896 46.755  1.00 109.60 ? 225 ARG B CG  1 
ATOM   5570  C CD  . ARG B 1 165 ? -33.478  -19.950 47.187  1.00 98.46  ? 225 ARG B CD  1 
ATOM   5571  N NE  . ARG B 1 165 ? -33.027  -18.586 47.476  1.00 84.48  ? 225 ARG B NE  1 
ATOM   5572  C CZ  . ARG B 1 165 ? -32.857  -18.034 48.670  1.00 72.58  ? 225 ARG B CZ  1 
ATOM   5573  N NH1 . ARG B 1 165 ? -33.092  -18.694 49.777  1.00 64.36  ? 225 ARG B NH1 1 
ATOM   5574  N NH2 . ARG B 1 165 ? -32.444  -16.786 48.757  1.00 89.98  ? 225 ARG B NH2 1 
ATOM   5575  N N   . ASN B 1 166 ? -30.276  -21.096 49.350  1.00 77.56  ? 226 ASN B N   1 
ATOM   5576  C CA  . ASN B 1 166 ? -28.885  -20.648 49.618  1.00 75.74  ? 226 ASN B CA  1 
ATOM   5577  C C   . ASN B 1 166 ? -28.514  -20.910 51.090  1.00 72.34  ? 226 ASN B C   1 
ATOM   5578  O O   . ASN B 1 166 ? -28.466  -19.948 51.873  1.00 78.65  ? 226 ASN B O   1 
ATOM   5579  C CB  . ASN B 1 166 ? -28.773  -19.172 49.221  1.00 92.75  ? 226 ASN B CB  1 
ATOM   5580  C CG  . ASN B 1 166 ? -27.428  -18.513 49.497  1.00 103.12 ? 226 ASN B CG  1 
ATOM   5581  O OD1 . ASN B 1 166 ? -26.394  -19.156 49.718  1.00 100.57 ? 226 ASN B OD1 1 
ATOM   5582  N ND2 . ASN B 1 166 ? -27.413  -17.189 49.431  1.00 91.18  ? 226 ASN B ND2 1 
ATOM   5583  N N   . ILE B 1 167 ? -28.249  -22.162 51.476  1.00 75.29  ? 227 ILE B N   1 
ATOM   5584  C CA  . ILE B 1 167 ? -27.884  -22.514 52.886  1.00 72.84  ? 227 ILE B CA  1 
ATOM   5585  C C   . ILE B 1 167 ? -26.354  -22.520 53.027  1.00 71.49  ? 227 ILE B C   1 
ATOM   5586  O O   . ILE B 1 167 ? -25.689  -23.228 52.225  1.00 73.40  ? 227 ILE B O   1 
ATOM   5587  C CB  . ILE B 1 167 ? -28.531  -23.855 53.291  1.00 71.82  ? 227 ILE B CB  1 
ATOM   5588  C CG1 . ILE B 1 167 ? -30.052  -23.707 53.354  1.00 79.32  ? 227 ILE B CG1 1 
ATOM   5589  C CG2 . ILE B 1 167 ? -27.968  -24.384 54.603  1.00 66.81  ? 227 ILE B CG2 1 
ATOM   5590  C CD1 . ILE B 1 167 ? -30.526  -22.492 54.165  1.00 81.51  ? 227 ILE B CD1 1 
ATOM   5591  N N   . GLN B 1 168 ? -25.834  -21.768 54.008  1.00 67.96  ? 228 GLN B N   1 
ATOM   5592  C CA  . GLN B 1 168 ? -24.384  -21.611 54.326  1.00 67.87  ? 228 GLN B CA  1 
ATOM   5593  C C   . GLN B 1 168 ? -24.018  -22.329 55.640  1.00 66.78  ? 228 GLN B C   1 
ATOM   5594  O O   . GLN B 1 168 ? -22.909  -22.903 55.699  1.00 71.62  ? 228 GLN B O   1 
ATOM   5595  C CB  . GLN B 1 168 ? -24.033  -20.126 54.432  1.00 67.99  ? 228 GLN B CB  1 
ATOM   5596  C CG  . GLN B 1 168 ? -24.087  -19.403 53.094  1.00 72.07  ? 228 GLN B CG  1 
ATOM   5597  C CD  . GLN B 1 168 ? -23.841  -17.914 53.180  1.00 74.98  ? 228 GLN B CD  1 
ATOM   5598  O OE1 . GLN B 1 168 ? -23.621  -17.326 54.235  1.00 74.97  ? 228 GLN B OE1 1 
ATOM   5599  N NE2 . GLN B 1 168 ? -23.995  -17.257 52.051  1.00 76.75  ? 228 GLN B NE2 1 
ATOM   5600  N N   . VAL B 1 169 ? -24.891  -22.256 56.662  1.00 59.87  ? 229 VAL B N   1 
ATOM   5601  C CA  . VAL B 1 169 ? -24.703  -22.865 58.015  1.00 51.51  ? 229 VAL B CA  1 
ATOM   5602  C C   . VAL B 1 169 ? -25.851  -23.822 58.317  1.00 45.40  ? 229 VAL B C   1 
ATOM   5603  O O   . VAL B 1 169 ? -26.996  -23.374 58.353  1.00 44.68  ? 229 VAL B O   1 
ATOM   5604  C CB  . VAL B 1 169 ? -24.637  -21.808 59.124  1.00 53.33  ? 229 VAL B CB  1 
ATOM   5605  C CG1 . VAL B 1 169 ? -24.274  -22.469 60.443  1.00 51.13  ? 229 VAL B CG1 1 
ATOM   5606  C CG2 . VAL B 1 169 ? -23.678  -20.677 58.787  1.00 59.21  ? 229 VAL B CG2 1 
ATOM   5607  N N   . ILE B 1 170 ? -25.541  -25.097 58.515  1.00 45.93  ? 230 ILE B N   1 
ATOM   5608  C CA  . ILE B 1 170 ? -26.487  -26.105 59.063  1.00 51.11  ? 230 ILE B CA  1 
ATOM   5609  C C   . ILE B 1 170 ? -26.044  -26.363 60.494  1.00 56.69  ? 230 ILE B C   1 
ATOM   5610  O O   . ILE B 1 170 ? -24.831  -26.363 60.721  1.00 62.25  ? 230 ILE B O   1 
ATOM   5611  C CB  . ILE B 1 170 ? -26.515  -27.398 58.225  1.00 53.24  ? 230 ILE B CB  1 
ATOM   5612  C CG1 . ILE B 1 170 ? -27.227  -27.164 56.887  1.00 58.13  ? 230 ILE B CG1 1 
ATOM   5613  C CG2 . ILE B 1 170 ? -27.119  -28.559 59.027  1.00 50.92  ? 230 ILE B CG2 1 
ATOM   5614  C CD1 . ILE B 1 170 ? -27.019  -28.236 55.826  1.00 56.06  ? 230 ILE B CD1 1 
ATOM   5615  N N   . CYS B 1 171 ? -26.995  -26.524 61.412  1.00 60.49  ? 231 CYS B N   1 
ATOM   5616  C CA  . CYS B 1 171 ? -26.750  -26.969 62.797  1.00 59.13  ? 231 CYS B CA  1 
ATOM   5617  C C   . CYS B 1 171 ? -27.647  -28.179 63.084  1.00 53.25  ? 231 CYS B C   1 
ATOM   5618  O O   . CYS B 1 171 ? -28.862  -28.056 62.980  1.00 61.12  ? 231 CYS B O   1 
ATOM   5619  C CB  . CYS B 1 171 ? -26.977  -25.813 63.749  1.00 58.24  ? 231 CYS B CB  1 
ATOM   5620  S SG  . CYS B 1 171 ? -26.119  -26.099 65.308  1.00 94.30  ? 231 CYS B SG  1 
ATOM   5621  N N   . VAL B 1 172 ? -27.065  -29.325 63.386  1.00 47.71  ? 232 VAL B N   1 
ATOM   5622  C CA  . VAL B 1 172 ? -27.799  -30.620 63.361  1.00 49.49  ? 232 VAL B CA  1 
ATOM   5623  C C   . VAL B 1 172 ? -27.490  -31.400 64.631  1.00 48.91  ? 232 VAL B C   1 
ATOM   5624  O O   . VAL B 1 172 ? -26.319  -31.464 64.977  1.00 52.99  ? 232 VAL B O   1 
ATOM   5625  C CB  . VAL B 1 172 ? -27.404  -31.467 62.142  1.00 54.53  ? 232 VAL B CB  1 
ATOM   5626  C CG1 . VAL B 1 172 ? -25.905  -31.701 62.060  1.00 57.07  ? 232 VAL B CG1 1 
ATOM   5627  C CG2 . VAL B 1 172 ? -28.138  -32.781 62.131  1.00 52.87  ? 232 VAL B CG2 1 
ATOM   5628  N N   . THR B 1 173 ? -28.507  -31.994 65.265  1.00 48.98  ? 233 THR B N   1 
ATOM   5629  C CA  . THR B 1 173 ? -28.386  -32.902 66.443  1.00 45.98  ? 233 THR B CA  1 
ATOM   5630  C C   . THR B 1 173 ? -29.187  -34.180 66.183  1.00 43.54  ? 233 THR B C   1 
ATOM   5631  O O   . THR B 1 173 ? -30.136  -34.128 65.385  1.00 46.50  ? 233 THR B O   1 
ATOM   5632  C CB  . THR B 1 173 ? -28.876  -32.220 67.723  1.00 46.36  ? 233 THR B CB  1 
ATOM   5633  O OG1 . THR B 1 173 ? -28.939  -33.216 68.745  1.00 48.28  ? 233 THR B OG1 1 
ATOM   5634  C CG2 . THR B 1 173 ? -30.253  -31.620 67.613  1.00 47.36  ? 233 THR B CG2 1 
ATOM   5635  N N   . ASP B 1 174 ? -28.832  -35.299 66.796  1.00 44.33  ? 234 ASP B N   1 
ATOM   5636  C CA  . ASP B 1 174 ? -29.728  -36.487 66.767  1.00 52.62  ? 234 ASP B CA  1 
ATOM   5637  C C   . ASP B 1 174 ? -30.350  -36.640 68.156  1.00 54.94  ? 234 ASP B C   1 
ATOM   5638  O O   . ASP B 1 174 ? -31.076  -37.628 68.373  1.00 64.68  ? 234 ASP B O   1 
ATOM   5639  C CB  . ASP B 1 174 ? -29.032  -37.742 66.238  1.00 56.93  ? 234 ASP B CB  1 
ATOM   5640  C CG  . ASP B 1 174 ? -28.089  -38.370 67.243  1.00 65.34  ? 234 ASP B CG  1 
ATOM   5641  O OD1 . ASP B 1 174 ? -27.773  -37.676 68.206  1.00 73.59  ? 234 ASP B OD1 1 
ATOM   5642  O OD2 . ASP B 1 174 ? -27.692  -39.542 67.065  1.00 84.49  ? 234 ASP B OD2 1 
ATOM   5643  N N   . GLY B 1 175 ? -30.091  -35.669 69.025  1.00 51.11  ? 235 GLY B N   1 
ATOM   5644  C CA  . GLY B 1 175 ? -30.734  -35.529 70.333  1.00 54.54  ? 235 GLY B CA  1 
ATOM   5645  C C   . GLY B 1 175 ? -30.160  -36.434 71.419  1.00 57.93  ? 235 GLY B C   1 
ATOM   5646  O O   . GLY B 1 175 ? -30.731  -36.399 72.540  1.00 61.36  ? 235 GLY B O   1 
ATOM   5647  N N   . GLU B 1 176 ? -29.091  -37.193 71.133  1.00 56.65  ? 236 GLU B N   1 
ATOM   5648  C CA  . GLU B 1 176 ? -28.537  -38.296 71.990  1.00 55.76  ? 236 GLU B CA  1 
ATOM   5649  C C   . GLU B 1 176 ? -28.016  -37.742 73.325  1.00 55.85  ? 236 GLU B C   1 
ATOM   5650  O O   . GLU B 1 176 ? -28.153  -38.446 74.347  1.00 61.66  ? 236 GLU B O   1 
ATOM   5651  C CB  . GLU B 1 176 ? -27.236  -38.906 71.425  1.00 60.07  ? 236 GLU B CB  1 
ATOM   5652  C CG  . GLU B 1 176 ? -27.277  -40.244 70.671  1.00 65.08  ? 236 GLU B CG  1 
ATOM   5653  C CD  . GLU B 1 176 ? -27.143  -41.504 71.517  1.00 64.89  ? 236 GLU B CD  1 
ATOM   5654  O OE1 . GLU B 1 176 ? -26.760  -42.554 70.976  1.00 58.96  ? 236 GLU B OE1 1 
ATOM   5655  O OE2 . GLU B 1 176 ? -27.412  -41.421 72.719  1.00 62.95  ? 236 GLU B OE2 1 
ATOM   5656  N N   . ARG B 1 177 ? -27.367  -36.571 73.316  1.00 63.36  ? 237 ARG B N   1 
ATOM   5657  C CA  . ARG B 1 177 ? -26.757  -35.988 74.544  1.00 73.30  ? 237 ARG B CA  1 
ATOM   5658  C C   . ARG B 1 177 ? -27.023  -34.488 74.582  1.00 65.71  ? 237 ARG B C   1 
ATOM   5659  O O   . ARG B 1 177 ? -26.056  -33.742 74.429  1.00 56.44  ? 237 ARG B O   1 
ATOM   5660  C CB  . ARG B 1 177 ? -25.248  -36.258 74.616  1.00 77.12  ? 237 ARG B CB  1 
ATOM   5661  C CG  . ARG B 1 177 ? -24.873  -37.710 74.845  1.00 77.02  ? 237 ARG B CG  1 
ATOM   5662  C CD  . ARG B 1 177 ? -23.593  -37.798 75.654  1.00 90.18  ? 237 ARG B CD  1 
ATOM   5663  N NE  . ARG B 1 177 ? -23.046  -39.151 75.636  1.00 110.60 ? 237 ARG B NE  1 
ATOM   5664  C CZ  . ARG B 1 177 ? -21.802  -39.504 75.991  1.00 96.10  ? 237 ARG B CZ  1 
ATOM   5665  N NH1 . ARG B 1 177 ? -20.941  -38.575 76.389  1.00 86.92  ? 237 ARG B NH1 1 
ATOM   5666  N NH2 . ARG B 1 177 ? -21.435  -40.787 75.936  1.00 80.66  ? 237 ARG B NH2 1 
ATOM   5667  N N   . ILE B 1 178 ? -28.267  -34.065 74.829  1.00 67.79  ? 238 ILE B N   1 
ATOM   5668  C CA  . ILE B 1 178 ? -28.579  -32.603 74.884  1.00 63.87  ? 238 ILE B CA  1 
ATOM   5669  C C   . ILE B 1 178 ? -28.018  -32.048 76.199  1.00 55.34  ? 238 ILE B C   1 
ATOM   5670  O O   . ILE B 1 178 ? -28.464  -32.494 77.248  1.00 69.07  ? 238 ILE B O   1 
ATOM   5671  C CB  . ILE B 1 178 ? -30.055  -32.244 74.583  1.00 65.57  ? 238 ILE B CB  1 
ATOM   5672  C CG1 . ILE B 1 178 ? -30.266  -31.972 73.088  1.00 64.93  ? 238 ILE B CG1 1 
ATOM   5673  C CG2 . ILE B 1 178 ? -30.527  -30.982 75.307  1.00 77.72  ? 238 ILE B CG2 1 
ATOM   5674  C CD1 . ILE B 1 178 ? -30.632  -33.148 72.294  1.00 63.00  ? 238 ILE B CD1 1 
ATOM   5675  N N   . LEU B 1 179 ? -27.038  -31.150 76.115  1.00 55.80  ? 239 LEU B N   1 
ATOM   5676  C CA  . LEU B 1 179 ? -26.286  -30.618 77.280  1.00 60.57  ? 239 LEU B CA  1 
ATOM   5677  C C   . LEU B 1 179 ? -25.882  -31.805 78.188  1.00 64.69  ? 239 LEU B C   1 
ATOM   5678  O O   . LEU B 1 179 ? -25.547  -32.871 77.648  1.00 66.32  ? 239 LEU B O   1 
ATOM   5679  C CB  . LEU B 1 179 ? -27.195  -29.586 77.962  1.00 52.23  ? 239 LEU B CB  1 
ATOM   5680  C CG  . LEU B 1 179 ? -27.288  -28.231 77.275  1.00 44.62  ? 239 LEU B CG  1 
ATOM   5681  C CD1 . LEU B 1 179 ? -27.275  -28.328 75.779  1.00 46.04  ? 239 LEU B CD1 1 
ATOM   5682  C CD2 . LEU B 1 179 ? -28.514  -27.475 77.725  1.00 45.95  ? 239 LEU B CD2 1 
ATOM   5683  N N   . GLY B 1 180 ? -25.948  -31.659 79.513  1.00 66.78  ? 240 GLY B N   1 
ATOM   5684  C CA  . GLY B 1 180 ? -25.766  -32.783 80.446  1.00 60.68  ? 240 GLY B CA  1 
ATOM   5685  C C   . GLY B 1 180 ? -27.082  -33.428 80.846  1.00 60.93  ? 240 GLY B C   1 
ATOM   5686  O O   . GLY B 1 180 ? -27.127  -34.022 81.961  1.00 74.33  ? 240 GLY B O   1 
ATOM   5687  N N   . LEU B 1 181 ? -28.127  -33.336 80.011  1.00 58.58  ? 241 LEU B N   1 
ATOM   5688  C CA  . LEU B 1 181 ? -29.491  -33.868 80.321  1.00 57.33  ? 241 LEU B CA  1 
ATOM   5689  C C   . LEU B 1 181 ? -29.714  -35.253 79.683  1.00 58.68  ? 241 LEU B C   1 
ATOM   5690  O O   . LEU B 1 181 ? -30.760  -35.858 79.946  1.00 54.52  ? 241 LEU B O   1 
ATOM   5691  C CB  . LEU B 1 181 ? -30.517  -32.851 79.829  1.00 46.94  ? 241 LEU B CB  1 
ATOM   5692  C CG  . LEU B 1 181 ? -30.333  -31.449 80.396  1.00 53.27  ? 241 LEU B CG  1 
ATOM   5693  C CD1 . LEU B 1 181 ? -31.343  -30.486 79.810  1.00 56.33  ? 241 LEU B CD1 1 
ATOM   5694  C CD2 . LEU B 1 181 ? -30.491  -31.452 81.905  1.00 62.29  ? 241 LEU B CD2 1 
ATOM   5695  N N   . GLY B 1 182 ? -28.752  -35.748 78.898  1.00 57.37  ? 242 GLY B N   1 
ATOM   5696  C CA  . GLY B 1 182 ? -28.863  -37.032 78.193  1.00 64.52  ? 242 GLY B CA  1 
ATOM   5697  C C   . GLY B 1 182 ? -29.792  -36.965 76.979  1.00 74.67  ? 242 GLY B C   1 
ATOM   5698  O O   . GLY B 1 182 ? -29.855  -35.893 76.290  1.00 86.94  ? 242 GLY B O   1 
ATOM   5699  N N   . ASP B 1 183 ? -30.481  -38.085 76.722  1.00 72.35  ? 243 ASP B N   1 
ATOM   5700  C CA  . ASP B 1 183 ? -31.249  -38.411 75.491  1.00 65.63  ? 243 ASP B CA  1 
ATOM   5701  C C   . ASP B 1 183 ? -32.646  -37.765 75.545  1.00 68.26  ? 243 ASP B C   1 
ATOM   5702  O O   . ASP B 1 183 ? -33.503  -38.214 76.344  1.00 71.06  ? 243 ASP B O   1 
ATOM   5703  C CB  . ASP B 1 183 ? -31.319  -39.934 75.361  1.00 63.81  ? 243 ASP B CB  1 
ATOM   5704  C CG  . ASP B 1 183 ? -31.839  -40.438 74.042  1.00 57.86  ? 243 ASP B CG  1 
ATOM   5705  O OD1 . ASP B 1 183 ? -32.446  -39.626 73.317  1.00 62.03  ? 243 ASP B OD1 1 
ATOM   5706  O OD2 . ASP B 1 183 ? -31.608  -41.638 73.758  1.00 53.62  ? 243 ASP B OD2 1 
ATOM   5707  N N   . LEU B 1 184 ? -32.884  -36.738 74.729  1.00 64.28  ? 244 LEU B N   1 
ATOM   5708  C CA  . LEU B 1 184 ? -34.224  -36.091 74.623  1.00 58.43  ? 244 LEU B CA  1 
ATOM   5709  C C   . LEU B 1 184 ? -34.775  -36.362 73.223  1.00 63.00  ? 244 LEU B C   1 
ATOM   5710  O O   . LEU B 1 184 ? -35.727  -35.663 72.780  1.00 69.41  ? 244 LEU B O   1 
ATOM   5711  C CB  . LEU B 1 184 ? -34.106  -34.596 74.930  1.00 50.75  ? 244 LEU B CB  1 
ATOM   5712  C CG  . LEU B 1 184 ? -33.700  -34.270 76.362  1.00 47.43  ? 244 LEU B CG  1 
ATOM   5713  C CD1 . LEU B 1 184 ? -33.709  -32.779 76.600  1.00 45.56  ? 244 LEU B CD1 1 
ATOM   5714  C CD2 . LEU B 1 184 ? -34.626  -34.965 77.337  1.00 47.22  ? 244 LEU B CD2 1 
ATOM   5715  N N   . GLY B 1 185 ? -34.217  -37.373 72.557  1.00 57.12  ? 245 GLY B N   1 
ATOM   5716  C CA  . GLY B 1 185 ? -34.671  -37.772 71.219  1.00 60.69  ? 245 GLY B CA  1 
ATOM   5717  C C   . GLY B 1 185 ? -35.011  -36.556 70.383  1.00 61.89  ? 245 GLY B C   1 
ATOM   5718  O O   . GLY B 1 185 ? -34.239  -35.551 70.418  1.00 50.79  ? 245 GLY B O   1 
ATOM   5719  N N   . CYS B 1 186 ? -36.164  -36.613 69.717  1.00 58.47  ? 246 CYS B N   1 
ATOM   5720  C CA  . CYS B 1 186 ? -36.590  -35.643 68.685  1.00 54.74  ? 246 CYS B CA  1 
ATOM   5721  C C   . CYS B 1 186 ? -36.760  -34.236 69.302  1.00 56.79  ? 246 CYS B C   1 
ATOM   5722  O O   . CYS B 1 186 ? -36.820  -33.220 68.538  1.00 47.99  ? 246 CYS B O   1 
ATOM   5723  C CB  . CYS B 1 186 ? -37.867  -36.139 68.034  1.00 43.89  ? 246 CYS B CB  1 
ATOM   5724  S SG  . CYS B 1 186 ? -38.135  -35.432 66.401  1.00 56.81  ? 246 CYS B SG  1 
ATOM   5725  N N   . GLN B 1 187 ? -36.833  -34.145 70.634  1.00 48.11  ? 247 GLN B N   1 
ATOM   5726  C CA  . GLN B 1 187 ? -37.065  -32.848 71.321  1.00 57.44  ? 247 GLN B CA  1 
ATOM   5727  C C   . GLN B 1 187 ? -35.737  -32.087 71.441  1.00 60.35  ? 247 GLN B C   1 
ATOM   5728  O O   . GLN B 1 187 ? -35.764  -30.957 71.974  1.00 59.25  ? 247 GLN B O   1 
ATOM   5729  C CB  . GLN B 1 187 ? -37.822  -33.073 72.637  1.00 53.26  ? 247 GLN B CB  1 
ATOM   5730  C CG  . GLN B 1 187 ? -39.247  -33.587 72.417  1.00 45.22  ? 247 GLN B CG  1 
ATOM   5731  C CD  . GLN B 1 187 ? -40.151  -33.535 73.612  1.00 43.23  ? 247 GLN B CD  1 
ATOM   5732  O OE1 . GLN B 1 187 ? -41.328  -33.852 73.497  1.00 51.32  ? 247 GLN B OE1 1 
ATOM   5733  N NE2 . GLN B 1 187 ? -39.626  -33.150 74.761  1.00 47.76  ? 247 GLN B NE2 1 
ATOM   5734  N N   . GLY B 1 188 ? -34.647  -32.650 70.901  1.00 55.66  ? 248 GLY B N   1 
ATOM   5735  C CA  . GLY B 1 188 ? -33.334  -31.986 70.807  1.00 52.34  ? 248 GLY B CA  1 
ATOM   5736  C C   . GLY B 1 188 ? -33.373  -30.698 70.000  1.00 57.02  ? 248 GLY B C   1 
ATOM   5737  O O   . GLY B 1 188 ? -32.443  -29.869 70.139  1.00 53.34  ? 248 GLY B O   1 
ATOM   5738  N N   . MET B 1 189 ? -34.421  -30.487 69.207  1.00 64.68  ? 249 MET B N   1 
ATOM   5739  C CA  . MET B 1 189 ? -34.469  -29.374 68.227  1.00 71.22  ? 249 MET B CA  1 
ATOM   5740  C C   . MET B 1 189 ? -34.214  -28.015 68.907  1.00 70.55  ? 249 MET B C   1 
ATOM   5741  O O   . MET B 1 189 ? -33.761  -27.084 68.212  1.00 77.61  ? 249 MET B O   1 
ATOM   5742  C CB  . MET B 1 189 ? -35.815  -29.377 67.499  1.00 72.16  ? 249 MET B CB  1 
ATOM   5743  C CG  . MET B 1 189 ? -35.997  -28.247 66.476  1.00 72.93  ? 249 MET B CG  1 
ATOM   5744  S SD  . MET B 1 189 ? -34.825  -28.318 65.147  1.00 64.83  ? 249 MET B SD  1 
ATOM   5745  C CE  . MET B 1 189 ? -35.759  -29.129 63.866  1.00 68.49  ? 249 MET B CE  1 
ATOM   5746  N N   . GLY B 1 190 ? -34.474  -27.869 70.202  1.00 66.47  ? 250 GLY B N   1 
ATOM   5747  C CA  . GLY B 1 190 ? -34.302  -26.568 70.873  1.00 73.06  ? 250 GLY B CA  1 
ATOM   5748  C C   . GLY B 1 190 ? -32.890  -26.016 70.702  1.00 71.06  ? 250 GLY B C   1 
ATOM   5749  O O   . GLY B 1 190 ? -32.739  -24.755 70.606  1.00 70.40  ? 250 GLY B O   1 
ATOM   5750  N N   . ILE B 1 191 ? -31.914  -26.932 70.663  1.00 63.15  ? 251 ILE B N   1 
ATOM   5751  C CA  . ILE B 1 191 ? -30.449  -26.653 70.638  1.00 62.79  ? 251 ILE B CA  1 
ATOM   5752  C C   . ILE B 1 191 ? -30.077  -26.069 69.267  1.00 55.57  ? 251 ILE B C   1 
ATOM   5753  O O   . ILE B 1 191 ? -29.661  -24.914 69.158  1.00 52.04  ? 251 ILE B O   1 
ATOM   5754  C CB  . ILE B 1 191 ? -29.648  -27.944 71.001  1.00 67.48  ? 251 ILE B CB  1 
ATOM   5755  C CG1 . ILE B 1 191 ? -29.906  -28.453 72.427  1.00 54.02  ? 251 ILE B CG1 1 
ATOM   5756  C CG2 . ILE B 1 191 ? -28.152  -27.751 70.742  1.00 71.76  ? 251 ILE B CG2 1 
ATOM   5757  C CD1 . ILE B 1 191 ? -29.667  -27.409 73.500  1.00 50.94  ? 251 ILE B CD1 1 
ATOM   5758  N N   . PRO B 1 192 ? -30.199  -26.836 68.159  1.00 54.11  ? 252 PRO B N   1 
ATOM   5759  C CA  . PRO B 1 192 ? -29.862  -26.296 66.845  1.00 53.84  ? 252 PRO B CA  1 
ATOM   5760  C C   . PRO B 1 192 ? -30.521  -24.936 66.602  1.00 50.34  ? 252 PRO B C   1 
ATOM   5761  O O   . PRO B 1 192 ? -29.872  -24.075 66.034  1.00 52.33  ? 252 PRO B O   1 
ATOM   5762  C CB  . PRO B 1 192 ? -30.414  -27.339 65.867  1.00 54.59  ? 252 PRO B CB  1 
ATOM   5763  C CG  . PRO B 1 192 ? -30.373  -28.627 66.659  1.00 55.77  ? 252 PRO B CG  1 
ATOM   5764  C CD  . PRO B 1 192 ? -30.638  -28.241 68.094  1.00 49.36  ? 252 PRO B CD  1 
ATOM   5765  N N   . VAL B 1 193 ? -31.776  -24.772 67.027  1.00 48.55  ? 253 VAL B N   1 
ATOM   5766  C CA  . VAL B 1 193 ? -32.532  -23.517 66.768  1.00 54.81  ? 253 VAL B CA  1 
ATOM   5767  C C   . VAL B 1 193 ? -31.856  -22.423 67.587  1.00 53.74  ? 253 VAL B C   1 
ATOM   5768  O O   . VAL B 1 193 ? -31.709  -21.281 67.090  1.00 55.93  ? 253 VAL B O   1 
ATOM   5769  C CB  . VAL B 1 193 ? -34.040  -23.632 67.065  1.00 62.07  ? 253 VAL B CB  1 
ATOM   5770  C CG1 . VAL B 1 193 ? -34.708  -22.259 66.897  1.00 67.09  ? 253 VAL B CG1 1 
ATOM   5771  C CG2 . VAL B 1 193 ? -34.733  -24.688 66.183  1.00 54.03  ? 253 VAL B CG2 1 
ATOM   5772  N N   . GLY B 1 194 ? -31.413  -22.782 68.780  1.00 51.58  ? 254 GLY B N   1 
ATOM   5773  C CA  . GLY B 1 194 ? -30.730  -21.840 69.675  1.00 56.90  ? 254 GLY B CA  1 
ATOM   5774  C C   . GLY B 1 194 ? -29.412  -21.405 69.097  1.00 53.12  ? 254 GLY B C   1 
ATOM   5775  O O   . GLY B 1 194 ? -29.205  -20.193 68.958  1.00 59.41  ? 254 GLY B O   1 
ATOM   5776  N N   . LYS B 1 195 ? -28.555  -22.373 68.789  1.00 49.30  ? 255 LYS B N   1 
ATOM   5777  C CA  . LYS B 1 195 ? -27.192  -22.115 68.260  1.00 45.87  ? 255 LYS B CA  1 
ATOM   5778  C C   . LYS B 1 195 ? -27.309  -21.125 67.100  1.00 45.34  ? 255 LYS B C   1 
ATOM   5779  O O   . LYS B 1 195 ? -26.658  -20.080 67.129  1.00 41.36  ? 255 LYS B O   1 
ATOM   5780  C CB  . LYS B 1 195 ? -26.567  -23.421 67.773  1.00 45.63  ? 255 LYS B CB  1 
ATOM   5781  C CG  . LYS B 1 195 ? -26.290  -24.473 68.840  1.00 49.62  ? 255 LYS B CG  1 
ATOM   5782  C CD  . LYS B 1 195 ? -25.055  -24.200 69.685  1.00 52.06  ? 255 LYS B CD  1 
ATOM   5783  C CE  . LYS B 1 195 ? -25.053  -25.058 70.932  1.00 52.99  ? 255 LYS B CE  1 
ATOM   5784  N NZ  . LYS B 1 195 ? -23.812  -24.875 71.708  1.00 53.15  ? 255 LYS B NZ  1 
ATOM   5785  N N   . LEU B 1 196 ? -28.182  -21.434 66.144  1.00 47.38  ? 256 LEU B N   1 
ATOM   5786  C CA  . LEU B 1 196 ? -28.284  -20.700 64.866  1.00 46.07  ? 256 LEU B CA  1 
ATOM   5787  C C   . LEU B 1 196 ? -28.805  -19.278 65.110  1.00 46.82  ? 256 LEU B C   1 
ATOM   5788  O O   . LEU B 1 196 ? -28.349  -18.366 64.427  1.00 44.77  ? 256 LEU B O   1 
ATOM   5789  C CB  . LEU B 1 196 ? -29.156  -21.513 63.911  1.00 44.80  ? 256 LEU B CB  1 
ATOM   5790  C CG  . LEU B 1 196 ? -28.475  -22.747 63.329  1.00 50.32  ? 256 LEU B CG  1 
ATOM   5791  C CD1 . LEU B 1 196 ? -29.411  -23.502 62.387  1.00 56.79  ? 256 LEU B CD1 1 
ATOM   5792  C CD2 . LEU B 1 196 ? -27.188  -22.361 62.598  1.00 47.98  ? 256 LEU B CD2 1 
ATOM   5793  N N   . ALA B 1 197 ? -29.689  -19.073 66.079  1.00 51.52  ? 257 ALA B N   1 
ATOM   5794  C CA  . ALA B 1 197 ? -30.128  -17.722 66.490  1.00 55.63  ? 257 ALA B CA  1 
ATOM   5795  C C   . ALA B 1 197 ? -28.891  -16.943 66.930  1.00 59.57  ? 257 ALA B C   1 
ATOM   5796  O O   . ALA B 1 197 ? -28.795  -15.741 66.637  1.00 63.44  ? 257 ALA B O   1 
ATOM   5797  C CB  . ALA B 1 197 ? -31.150  -17.807 67.595  1.00 57.54  ? 257 ALA B CB  1 
ATOM   5798  N N   . LEU B 1 198 ? -27.972  -17.626 67.613  1.00 61.54  ? 258 LEU B N   1 
ATOM   5799  C CA  . LEU B 1 198 ? -26.750  -17.007 68.180  1.00 57.60  ? 258 LEU B CA  1 
ATOM   5800  C C   . LEU B 1 198 ? -25.780  -16.733 67.037  1.00 52.77  ? 258 LEU B C   1 
ATOM   5801  O O   . LEU B 1 198 ? -25.175  -15.656 66.994  1.00 49.09  ? 258 LEU B O   1 
ATOM   5802  C CB  . LEU B 1 198 ? -26.151  -17.913 69.264  1.00 64.75  ? 258 LEU B CB  1 
ATOM   5803  C CG  . LEU B 1 198 ? -26.727  -17.687 70.676  1.00 72.53  ? 258 LEU B CG  1 
ATOM   5804  C CD1 . LEU B 1 198 ? -27.780  -18.738 70.991  1.00 85.55  ? 258 LEU B CD1 1 
ATOM   5805  C CD2 . LEU B 1 198 ? -25.655  -17.703 71.776  1.00 77.16  ? 258 LEU B CD2 1 
ATOM   5806  N N   . TYR B 1 199 ? -25.671  -17.661 66.100  1.00 52.25  ? 259 TYR B N   1 
ATOM   5807  C CA  . TYR B 1 199 ? -24.881  -17.456 64.862  1.00 51.14  ? 259 TYR B CA  1 
ATOM   5808  C C   . TYR B 1 199 ? -25.236  -16.091 64.257  1.00 54.63  ? 259 TYR B C   1 
ATOM   5809  O O   . TYR B 1 199 ? -24.344  -15.496 63.630  1.00 50.89  ? 259 TYR B O   1 
ATOM   5810  C CB  . TYR B 1 199 ? -25.181  -18.543 63.839  1.00 46.88  ? 259 TYR B CB  1 
ATOM   5811  C CG  . TYR B 1 199 ? -24.117  -19.582 63.724  1.00 47.45  ? 259 TYR B CG  1 
ATOM   5812  C CD1 . TYR B 1 199 ? -22.936  -19.315 63.054  1.00 46.85  ? 259 TYR B CD1 1 
ATOM   5813  C CD2 . TYR B 1 199 ? -24.311  -20.842 64.264  1.00 51.44  ? 259 TYR B CD2 1 
ATOM   5814  C CE1 . TYR B 1 199 ? -21.968  -20.287 62.922  1.00 46.88  ? 259 TYR B CE1 1 
ATOM   5815  C CE2 . TYR B 1 199 ? -23.347  -21.828 64.148  1.00 50.23  ? 259 TYR B CE2 1 
ATOM   5816  C CZ  . TYR B 1 199 ? -22.177  -21.544 63.470  1.00 50.12  ? 259 TYR B CZ  1 
ATOM   5817  O OH  . TYR B 1 199 ? -21.250  -22.537 63.370  1.00 60.26  ? 259 TYR B OH  1 
ATOM   5818  N N   . THR B 1 200 ? -26.504  -15.659 64.375  1.00 48.09  ? 260 THR B N   1 
ATOM   5819  C CA  . THR B 1 200 ? -27.000  -14.406 63.758  1.00 48.26  ? 260 THR B CA  1 
ATOM   5820  C C   . THR B 1 200 ? -26.755  -13.248 64.727  1.00 46.68  ? 260 THR B C   1 
ATOM   5821  O O   . THR B 1 200 ? -26.237  -12.184 64.292  1.00 47.55  ? 260 THR B O   1 
ATOM   5822  C CB  . THR B 1 200 ? -28.493  -14.495 63.380  1.00 57.70  ? 260 THR B CB  1 
ATOM   5823  O OG1 . THR B 1 200 ? -28.721  -15.567 62.455  1.00 55.51  ? 260 THR B OG1 1 
ATOM   5824  C CG2 . THR B 1 200 ? -29.041  -13.192 62.815  1.00 52.56  ? 260 THR B CG2 1 
ATOM   5825  N N   . ALA B 1 201 ? -27.157  -13.434 65.978  1.00 44.30  ? 261 ALA B N   1 
ATOM   5826  C CA  . ALA B 1 201 ? -27.119  -12.397 67.022  1.00 50.53  ? 261 ALA B CA  1 
ATOM   5827  C C   . ALA B 1 201 ? -25.658  -12.086 67.381  1.00 57.48  ? 261 ALA B C   1 
ATOM   5828  O O   . ALA B 1 201 ? -25.309  -10.892 67.452  1.00 63.87  ? 261 ALA B O   1 
ATOM   5829  C CB  . ALA B 1 201 ? -27.914  -12.855 68.216  1.00 49.27  ? 261 ALA B CB  1 
ATOM   5830  N N   . LEU B 1 202 ? -24.830  -13.119 67.578  1.00 57.89  ? 262 LEU B N   1 
ATOM   5831  C CA  . LEU B 1 202 ? -23.426  -12.998 68.063  1.00 59.50  ? 262 LEU B CA  1 
ATOM   5832  C C   . LEU B 1 202 ? -22.450  -12.875 66.892  1.00 61.44  ? 262 LEU B C   1 
ATOM   5833  O O   . LEU B 1 202 ? -21.492  -12.121 67.037  1.00 66.58  ? 262 LEU B O   1 
ATOM   5834  C CB  . LEU B 1 202 ? -23.064  -14.204 68.928  1.00 62.08  ? 262 LEU B CB  1 
ATOM   5835  C CG  . LEU B 1 202 ? -23.847  -14.348 70.230  1.00 64.71  ? 262 LEU B CG  1 
ATOM   5836  C CD1 . LEU B 1 202 ? -24.201  -13.026 70.888  1.00 68.20  ? 262 LEU B CD1 1 
ATOM   5837  C CD2 . LEU B 1 202 ? -25.106  -15.108 69.996  1.00 76.73  ? 262 LEU B CD2 1 
ATOM   5838  N N   . GLY B 1 203 ? -22.670  -13.619 65.812  1.00 63.79  ? 263 GLY B N   1 
ATOM   5839  C CA  . GLY B 1 203 ? -21.735  -13.724 64.669  1.00 61.46  ? 263 GLY B CA  1 
ATOM   5840  C C   . GLY B 1 203 ? -22.074  -12.819 63.480  1.00 54.30  ? 263 GLY B C   1 
ATOM   5841  O O   . GLY B 1 203 ? -21.150  -12.499 62.729  1.00 66.21  ? 263 GLY B O   1 
ATOM   5842  N N   . GLY B 1 204 ? -23.344  -12.493 63.240  1.00 49.56  ? 264 GLY B N   1 
ATOM   5843  C CA  . GLY B 1 204 ? -23.777  -11.667 62.092  1.00 49.03  ? 264 GLY B CA  1 
ATOM   5844  C C   . GLY B 1 204 ? -24.074  -12.453 60.829  1.00 49.26  ? 264 GLY B C   1 
ATOM   5845  O O   . GLY B 1 204 ? -24.311  -11.815 59.790  1.00 51.57  ? 264 GLY B O   1 
ATOM   5846  N N   . VAL B 1 205 ? -24.112  -13.785 60.895  1.00 48.95  ? 265 VAL B N   1 
ATOM   5847  C CA  . VAL B 1 205 ? -24.610  -14.649 59.782  1.00 47.26  ? 265 VAL B CA  1 
ATOM   5848  C C   . VAL B 1 205 ? -26.065  -14.240 59.488  1.00 54.51  ? 265 VAL B C   1 
ATOM   5849  O O   . VAL B 1 205 ? -26.816  -14.119 60.432  1.00 69.75  ? 265 VAL B O   1 
ATOM   5850  C CB  . VAL B 1 205 ? -24.523  -16.131 60.201  1.00 46.14  ? 265 VAL B CB  1 
ATOM   5851  C CG1 . VAL B 1 205 ? -24.919  -17.103 59.100  1.00 43.74  ? 265 VAL B CG1 1 
ATOM   5852  C CG2 . VAL B 1 205 ? -23.154  -16.470 60.745  1.00 49.16  ? 265 VAL B CG2 1 
ATOM   5853  N N   . ASP B 1 206 ? -26.476  -14.057 58.237  1.00 57.03  ? 266 ASP B N   1 
ATOM   5854  C CA  . ASP B 1 206 ? -27.908  -13.825 57.883  1.00 64.14  ? 266 ASP B CA  1 
ATOM   5855  C C   . ASP B 1 206 ? -28.775  -15.012 58.338  1.00 79.68  ? 266 ASP B C   1 
ATOM   5856  O O   . ASP B 1 206 ? -28.390  -16.181 58.216  1.00 66.91  ? 266 ASP B O   1 
ATOM   5857  C CB  . ASP B 1 206 ? -28.061  -13.517 56.393  1.00 65.69  ? 266 ASP B CB  1 
ATOM   5858  C CG  . ASP B 1 206 ? -29.451  -13.089 55.968  1.00 67.76  ? 266 ASP B CG  1 
ATOM   5859  O OD1 . ASP B 1 206 ? -30.115  -12.357 56.706  1.00 74.55  ? 266 ASP B OD1 1 
ATOM   5860  O OD2 . ASP B 1 206 ? -29.852  -13.483 54.877  1.00 75.51  ? 266 ASP B OD2 1 
ATOM   5861  N N   . PRO B 1 207 ? -29.978  -14.759 58.923  1.00 78.96  ? 267 PRO B N   1 
ATOM   5862  C CA  . PRO B 1 207 ? -30.855  -15.848 59.361  1.00 60.32  ? 267 PRO B CA  1 
ATOM   5863  C C   . PRO B 1 207 ? -31.207  -16.811 58.222  1.00 55.04  ? 267 PRO B C   1 
ATOM   5864  O O   . PRO B 1 207 ? -31.301  -18.008 58.463  1.00 44.83  ? 267 PRO B O   1 
ATOM   5865  C CB  . PRO B 1 207 ? -32.129  -15.126 59.824  1.00 61.19  ? 267 PRO B CB  1 
ATOM   5866  C CG  . PRO B 1 207 ? -31.683  -13.712 60.172  1.00 60.73  ? 267 PRO B CG  1 
ATOM   5867  C CD  . PRO B 1 207 ? -30.521  -13.426 59.259  1.00 63.15  ? 267 PRO B CD  1 
ATOM   5868  N N   . SER B 1 208 ? -31.374  -16.258 57.012  1.00 54.05  ? 268 SER B N   1 
ATOM   5869  C CA  . SER B 1 208 ? -31.975  -16.947 55.848  1.00 59.74  ? 268 SER B CA  1 
ATOM   5870  C C   . SER B 1 208 ? -31.094  -18.101 55.414  1.00 59.28  ? 268 SER B C   1 
ATOM   5871  O O   . SER B 1 208 ? -31.645  -19.046 54.815  1.00 67.55  ? 268 SER B O   1 
ATOM   5872  C CB  . SER B 1 208 ? -32.201  -16.035 54.681  1.00 60.23  ? 268 SER B CB  1 
ATOM   5873  O OG  . SER B 1 208 ? -32.375  -14.695 55.106  1.00 73.11  ? 268 SER B OG  1 
ATOM   5874  N N   . VAL B 1 209 ? -29.795  -18.021 55.722  1.00 57.15  ? 269 VAL B N   1 
ATOM   5875  C CA  . VAL B 1 209 ? -28.780  -19.001 55.226  1.00 54.14  ? 269 VAL B CA  1 
ATOM   5876  C C   . VAL B 1 209 ? -28.562  -20.090 56.280  1.00 48.08  ? 269 VAL B C   1 
ATOM   5877  O O   . VAL B 1 209 ? -27.781  -20.994 55.978  1.00 39.93  ? 269 VAL B O   1 
ATOM   5878  C CB  . VAL B 1 209 ? -27.464  -18.296 54.835  1.00 54.46  ? 269 VAL B CB  1 
ATOM   5879  C CG1 . VAL B 1 209 ? -27.695  -17.174 53.846  1.00 54.34  ? 269 VAL B CG1 1 
ATOM   5880  C CG2 . VAL B 1 209 ? -26.715  -17.734 56.030  1.00 63.00  ? 269 VAL B CG2 1 
ATOM   5881  N N   . CYS B 1 210 ? -29.257  -20.006 57.426  1.00 51.16  ? 270 CYS B N   1 
ATOM   5882  C CA  . CYS B 1 210 ? -29.119  -20.916 58.596  1.00 50.91  ? 270 CYS B CA  1 
ATOM   5883  C C   . CYS B 1 210 ? -30.258  -21.937 58.595  1.00 47.14  ? 270 CYS B C   1 
ATOM   5884  O O   . CYS B 1 210 ? -31.359  -21.527 58.329  1.00 51.54  ? 270 CYS B O   1 
ATOM   5885  C CB  . CYS B 1 210 ? -29.146  -20.128 59.892  1.00 48.60  ? 270 CYS B CB  1 
ATOM   5886  S SG  . CYS B 1 210 ? -27.867  -18.852 59.944  1.00 62.54  ? 270 CYS B SG  1 
ATOM   5887  N N   . LEU B 1 211 ? -29.968  -23.216 58.829  1.00 44.09  ? 271 LEU B N   1 
ATOM   5888  C CA  . LEU B 1 211 ? -30.951  -24.315 58.688  1.00 47.43  ? 271 LEU B CA  1 
ATOM   5889  C C   . LEU B 1 211 ? -30.858  -25.255 59.889  1.00 45.60  ? 271 LEU B C   1 
ATOM   5890  O O   . LEU B 1 211 ? -29.977  -26.099 59.953  1.00 45.82  ? 271 LEU B O   1 
ATOM   5891  C CB  . LEU B 1 211 ? -30.689  -25.063 57.377  1.00 49.45  ? 271 LEU B CB  1 
ATOM   5892  C CG  . LEU B 1 211 ? -31.418  -26.409 57.229  1.00 53.20  ? 271 LEU B CG  1 
ATOM   5893  C CD1 . LEU B 1 211 ? -32.911  -26.222 57.351  1.00 57.57  ? 271 LEU B CD1 1 
ATOM   5894  C CD2 . LEU B 1 211 ? -31.113  -27.106 55.914  1.00 52.07  ? 271 LEU B CD2 1 
ATOM   5895  N N   . PRO B 1 212 ? -31.769  -25.157 60.880  1.00 39.98  ? 272 PRO B N   1 
ATOM   5896  C CA  . PRO B 1 212 ? -31.718  -26.038 62.035  1.00 38.94  ? 272 PRO B CA  1 
ATOM   5897  C C   . PRO B 1 212 ? -32.287  -27.397 61.664  1.00 37.57  ? 272 PRO B C   1 
ATOM   5898  O O   . PRO B 1 212 ? -33.351  -27.421 61.175  1.00 38.82  ? 272 PRO B O   1 
ATOM   5899  C CB  . PRO B 1 212 ? -32.574  -25.349 63.096  1.00 37.50  ? 272 PRO B CB  1 
ATOM   5900  C CG  . PRO B 1 212 ? -33.153  -24.117 62.442  1.00 35.43  ? 272 PRO B CG  1 
ATOM   5901  C CD  . PRO B 1 212 ? -32.876  -24.205 60.963  1.00 37.26  ? 272 PRO B CD  1 
ATOM   5902  N N   . ILE B 1 213 ? -31.544  -28.468 61.874  1.00 46.53  ? 273 ILE B N   1 
ATOM   5903  C CA  . ILE B 1 213 ? -32.002  -29.844 61.525  1.00 50.44  ? 273 ILE B CA  1 
ATOM   5904  C C   . ILE B 1 213 ? -31.967  -30.723 62.770  1.00 47.58  ? 273 ILE B C   1 
ATOM   5905  O O   . ILE B 1 213 ? -31.047  -30.583 63.568  1.00 55.00  ? 273 ILE B O   1 
ATOM   5906  C CB  . ILE B 1 213 ? -31.146  -30.426 60.390  1.00 49.77  ? 273 ILE B CB  1 
ATOM   5907  C CG1 . ILE B 1 213 ? -31.214  -29.505 59.164  1.00 47.56  ? 273 ILE B CG1 1 
ATOM   5908  C CG2 . ILE B 1 213 ? -31.545  -31.881 60.113  1.00 49.99  ? 273 ILE B CG2 1 
ATOM   5909  C CD1 . ILE B 1 213 ? -30.358  -29.947 57.993  1.00 50.83  ? 273 ILE B CD1 1 
ATOM   5910  N N   . THR B 1 214 ? -32.931  -31.612 62.905  1.00 42.72  ? 274 THR B N   1 
ATOM   5911  C CA  . THR B 1 214 ? -32.888  -32.699 63.899  1.00 46.75  ? 274 THR B CA  1 
ATOM   5912  C C   . THR B 1 214 ? -33.027  -34.016 63.156  1.00 45.31  ? 274 THR B C   1 
ATOM   5913  O O   . THR B 1 214 ? -33.980  -34.148 62.368  1.00 47.82  ? 274 THR B O   1 
ATOM   5914  C CB  . THR B 1 214 ? -33.996  -32.550 64.950  1.00 54.54  ? 274 THR B CB  1 
ATOM   5915  O OG1 . THR B 1 214 ? -33.815  -31.304 65.639  1.00 46.35  ? 274 THR B OG1 1 
ATOM   5916  C CG2 . THR B 1 214 ? -34.031  -33.736 65.905  1.00 55.72  ? 274 THR B CG2 1 
ATOM   5917  N N   . ILE B 1 215 ? -32.135  -34.963 63.409  1.00 45.81  ? 275 ILE B N   1 
ATOM   5918  C CA  . ILE B 1 215 ? -32.293  -36.347 62.884  1.00 49.95  ? 275 ILE B CA  1 
ATOM   5919  C C   . ILE B 1 215 ? -32.985  -37.201 63.945  1.00 49.15  ? 275 ILE B C   1 
ATOM   5920  O O   . ILE B 1 215 ? -32.342  -37.484 64.943  1.00 50.61  ? 275 ILE B O   1 
ATOM   5921  C CB  . ILE B 1 215 ? -30.923  -36.881 62.455  1.00 51.33  ? 275 ILE B CB  1 
ATOM   5922  C CG1 . ILE B 1 215 ? -30.480  -36.094 61.225  1.00 55.32  ? 275 ILE B CG1 1 
ATOM   5923  C CG2 . ILE B 1 215 ? -30.937  -38.377 62.168  1.00 58.02  ? 275 ILE B CG2 1 
ATOM   5924  C CD1 . ILE B 1 215 ? -29.057  -35.734 61.249  1.00 66.24  ? 275 ILE B CD1 1 
ATOM   5925  N N   . ASP B 1 216 ? -34.239  -37.588 63.732  1.00 52.24  ? 276 ASP B N   1 
ATOM   5926  C CA  . ASP B 1 216 ? -34.977  -38.498 64.663  1.00 62.18  ? 276 ASP B CA  1 
ATOM   5927  C C   . ASP B 1 216 ? -34.737  -39.959 64.257  1.00 58.80  ? 276 ASP B C   1 
ATOM   5928  O O   . ASP B 1 216 ? -35.165  -40.365 63.172  1.00 53.47  ? 276 ASP B O   1 
ATOM   5929  C CB  . ASP B 1 216 ? -36.479  -38.186 64.712  1.00 61.42  ? 276 ASP B CB  1 
ATOM   5930  C CG  . ASP B 1 216 ? -37.295  -38.905 65.786  1.00 67.06  ? 276 ASP B CG  1 
ATOM   5931  O OD1 . ASP B 1 216 ? -36.700  -39.434 66.806  1.00 81.90  ? 276 ASP B OD1 1 
ATOM   5932  O OD2 . ASP B 1 216 ? -38.555  -38.905 65.618  1.00 55.80  ? 276 ASP B OD2 1 
ATOM   5933  N N   . VAL B 1 217 ? -34.069  -40.726 65.106  1.00 63.13  ? 277 VAL B N   1 
ATOM   5934  C CA  . VAL B 1 217 ? -33.824  -42.182 64.873  1.00 71.75  ? 277 VAL B CA  1 
ATOM   5935  C C   . VAL B 1 217 ? -34.453  -42.985 66.015  1.00 71.36  ? 277 VAL B C   1 
ATOM   5936  O O   . VAL B 1 217 ? -34.155  -44.198 66.127  1.00 76.85  ? 277 VAL B O   1 
ATOM   5937  C CB  . VAL B 1 217 ? -32.319  -42.462 64.746  1.00 70.82  ? 277 VAL B CB  1 
ATOM   5938  C CG1 . VAL B 1 217 ? -31.770  -41.877 63.467  1.00 70.97  ? 277 VAL B CG1 1 
ATOM   5939  C CG2 . VAL B 1 217 ? -31.546  -41.920 65.944  1.00 92.65  ? 277 VAL B CG2 1 
ATOM   5940  N N   . GLY B 1 218 ? -35.277  -42.321 66.832  1.00 64.36  ? 278 GLY B N   1 
ATOM   5941  C CA  . GLY B 1 218 ? -35.762  -42.858 68.110  1.00 62.79  ? 278 GLY B CA  1 
ATOM   5942  C C   . GLY B 1 218 ? -35.070  -42.211 69.299  1.00 60.20  ? 278 GLY B C   1 
ATOM   5943  O O   . GLY B 1 218 ? -34.269  -41.258 69.096  1.00 63.71  ? 278 GLY B O   1 
ATOM   5944  N N   . THR B 1 219 ? -35.385  -42.701 70.495  1.00 49.75  ? 279 THR B N   1 
ATOM   5945  C CA  . THR B 1 219 ? -34.835  -42.213 71.775  1.00 53.47  ? 279 THR B CA  1 
ATOM   5946  C C   . THR B 1 219 ? -34.920  -43.384 72.754  1.00 56.45  ? 279 THR B C   1 
ATOM   5947  O O   . THR B 1 219 ? -35.816  -44.215 72.558  1.00 53.36  ? 279 THR B O   1 
ATOM   5948  C CB  . THR B 1 219 ? -35.580  -40.956 72.268  1.00 47.05  ? 279 THR B CB  1 
ATOM   5949  O OG1 . THR B 1 219 ? -35.041  -40.518 73.523  1.00 40.99  ? 279 THR B OG1 1 
ATOM   5950  C CG2 . THR B 1 219 ? -37.064  -41.165 72.468  1.00 48.26  ? 279 THR B CG2 1 
ATOM   5951  N N   . ASN B 1 220 ? -34.032  -43.429 73.758  1.00 55.85  ? 280 ASN B N   1 
ATOM   5952  C CA  . ASN B 1 220 ? -34.008  -44.488 74.799  1.00 57.65  ? 280 ASN B CA  1 
ATOM   5953  C C   . ASN B 1 220 ? -34.677  -43.985 76.096  1.00 65.18  ? 280 ASN B C   1 
ATOM   5954  O O   . ASN B 1 220 ? -35.012  -44.837 76.967  1.00 65.46  ? 280 ASN B O   1 
ATOM   5955  C CB  . ASN B 1 220 ? -32.578  -44.967 75.011  1.00 53.55  ? 280 ASN B CB  1 
ATOM   5956  C CG  . ASN B 1 220 ? -31.999  -45.589 73.757  1.00 55.56  ? 280 ASN B CG  1 
ATOM   5957  O OD1 . ASN B 1 220 ? -32.703  -46.253 72.995  1.00 49.61  ? 280 ASN B OD1 1 
ATOM   5958  N ND2 . ASN B 1 220 ? -30.717  -45.396 73.531  1.00 53.38  ? 280 ASN B ND2 1 
ATOM   5959  N N   . ASN B 1 221 ? -34.853  -42.666 76.226  1.00 60.78  ? 281 ASN B N   1 
ATOM   5960  C CA  . ASN B 1 221 ? -35.594  -41.995 77.327  1.00 55.66  ? 281 ASN B CA  1 
ATOM   5961  C C   . ASN B 1 221 ? -37.005  -42.608 77.448  1.00 63.97  ? 281 ASN B C   1 
ATOM   5962  O O   . ASN B 1 221 ? -37.904  -42.248 76.653  1.00 65.84  ? 281 ASN B O   1 
ATOM   5963  C CB  . ASN B 1 221 ? -35.617  -40.493 77.056  1.00 56.31  ? 281 ASN B CB  1 
ATOM   5964  C CG  . ASN B 1 221 ? -36.127  -39.685 78.219  1.00 56.93  ? 281 ASN B CG  1 
ATOM   5965  O OD1 . ASN B 1 221 ? -36.886  -40.194 79.038  1.00 73.09  ? 281 ASN B OD1 1 
ATOM   5966  N ND2 . ASN B 1 221 ? -35.711  -38.438 78.295  1.00 60.34  ? 281 ASN B ND2 1 
ATOM   5967  N N   . GLU B 1 222 ? -37.195  -43.532 78.400  1.00 75.85  ? 282 GLU B N   1 
ATOM   5968  C CA  . GLU B 1 222 ? -38.461  -44.282 78.624  1.00 76.90  ? 282 GLU B CA  1 
ATOM   5969  C C   . GLU B 1 222 ? -39.586  -43.331 79.058  1.00 69.96  ? 282 GLU B C   1 
ATOM   5970  O O   . GLU B 1 222 ? -40.734  -43.635 78.701  1.00 72.95  ? 282 GLU B O   1 
ATOM   5971  C CB  . GLU B 1 222 ? -38.205  -45.386 79.648  1.00 84.69  ? 282 GLU B CB  1 
ATOM   5972  C CG  . GLU B 1 222 ? -37.529  -46.594 79.027  1.00 81.27  ? 282 GLU B CG  1 
ATOM   5973  C CD  . GLU B 1 222 ? -38.483  -47.451 78.203  1.00 95.44  ? 282 GLU B CD  1 
ATOM   5974  O OE1 . GLU B 1 222 ? -38.006  -48.431 77.595  1.00 96.67  ? 282 GLU B OE1 1 
ATOM   5975  O OE2 . GLU B 1 222 ? -39.716  -47.153 78.177  1.00 91.84  ? 282 GLU B OE2 1 
ATOM   5976  N N   . LYS B 1 223 ? -39.274  -42.261 79.809  1.00 56.67  ? 283 LYS B N   1 
ATOM   5977  C CA  . LYS B 1 223 ? -40.243  -41.195 80.195  1.00 58.17  ? 283 LYS B CA  1 
ATOM   5978  C C   . LYS B 1 223 ? -40.862  -40.559 78.933  1.00 65.54  ? 283 LYS B C   1 
ATOM   5979  O O   . LYS B 1 223 ? -42.077  -40.290 78.921  1.00 71.46  ? 283 LYS B O   1 
ATOM   5980  C CB  . LYS B 1 223 ? -39.567  -40.154 81.091  1.00 60.07  ? 283 LYS B CB  1 
ATOM   5981  C CG  . LYS B 1 223 ? -40.117  -38.735 80.966  1.00 71.48  ? 283 LYS B CG  1 
ATOM   5982  C CD  . LYS B 1 223 ? -39.036  -37.654 81.078  1.00 82.21  ? 283 LYS B CD  1 
ATOM   5983  C CE  . LYS B 1 223 ? -39.555  -36.242 80.837  1.00 85.70  ? 283 LYS B CE  1 
ATOM   5984  N NZ  . LYS B 1 223 ? -38.480  -35.296 80.423  1.00 78.26  ? 283 LYS B NZ  1 
ATOM   5985  N N   . LEU B 1 224 ? -40.064  -40.321 77.891  1.00 70.79  ? 284 LEU B N   1 
ATOM   5986  C CA  . LEU B 1 224 ? -40.527  -39.655 76.649  1.00 61.94  ? 284 LEU B CA  1 
ATOM   5987  C C   . LEU B 1 224 ? -41.251  -40.650 75.738  1.00 60.68  ? 284 LEU B C   1 
ATOM   5988  O O   . LEU B 1 224 ? -42.155  -40.218 75.025  1.00 70.51  ? 284 LEU B O   1 
ATOM   5989  C CB  . LEU B 1 224 ? -39.318  -39.054 75.935  1.00 66.55  ? 284 LEU B CB  1 
ATOM   5990  C CG  . LEU B 1 224 ? -38.755  -37.761 76.518  1.00 62.10  ? 284 LEU B CG  1 
ATOM   5991  C CD1 . LEU B 1 224 ? -37.731  -37.199 75.547  1.00 66.65  ? 284 LEU B CD1 1 
ATOM   5992  C CD2 . LEU B 1 224 ? -39.847  -36.728 76.810  1.00 53.32  ? 284 LEU B CD2 1 
ATOM   5993  N N   . LEU B 1 225 ? -40.862  -41.927 75.730  1.00 66.96  ? 285 LEU B N   1 
ATOM   5994  C CA  . LEU B 1 225 ? -41.580  -42.980 74.956  1.00 64.82  ? 285 LEU B CA  1 
ATOM   5995  C C   . LEU B 1 225 ? -43.019  -43.091 75.471  1.00 64.02  ? 285 LEU B C   1 
ATOM   5996  O O   . LEU B 1 225 ? -43.896  -43.320 74.656  1.00 89.48  ? 285 LEU B O   1 
ATOM   5997  C CB  . LEU B 1 225 ? -40.849  -44.320 75.048  1.00 57.98  ? 285 LEU B CB  1 
ATOM   5998  C CG  . LEU B 1 225 ? -39.614  -44.444 74.163  1.00 54.92  ? 285 LEU B CG  1 
ATOM   5999  C CD1 . LEU B 1 225 ? -39.028  -45.837 74.233  1.00 52.74  ? 285 LEU B CD1 1 
ATOM   6000  C CD2 . LEU B 1 225 ? -39.918  -44.118 72.716  1.00 63.81  ? 285 LEU B CD2 1 
ATOM   6001  N N   . ASN B 1 226 ? -43.249  -42.891 76.761  1.00 59.43  ? 286 ASN B N   1 
ATOM   6002  C CA  . ASN B 1 226 ? -44.565  -43.095 77.415  1.00 66.72  ? 286 ASN B CA  1 
ATOM   6003  C C   . ASN B 1 226 ? -45.277  -41.754 77.577  1.00 58.29  ? 286 ASN B C   1 
ATOM   6004  O O   . ASN B 1 226 ? -46.426  -41.790 77.969  1.00 63.61  ? 286 ASN B O   1 
ATOM   6005  C CB  . ASN B 1 226 ? -44.407  -43.797 78.769  1.00 74.44  ? 286 ASN B CB  1 
ATOM   6006  C CG  . ASN B 1 226 ? -43.978  -45.245 78.645  1.00 74.39  ? 286 ASN B CG  1 
ATOM   6007  O OD1 . ASN B 1 226 ? -43.390  -45.695 77.652  1.00 68.77  ? 286 ASN B OD1 1 
ATOM   6008  N ND2 . ASN B 1 226 ? -44.277  -46.004 79.681  1.00 75.65  ? 286 ASN B ND2 1 
ATOM   6009  N N   . ASP B 1 227 ? -44.610  -40.625 77.336  1.00 63.14  ? 287 ASP B N   1 
ATOM   6010  C CA  . ASP B 1 227 ? -45.220  -39.264 77.375  1.00 64.35  ? 287 ASP B CA  1 
ATOM   6011  C C   . ASP B 1 227 ? -46.038  -39.121 76.087  1.00 66.36  ? 287 ASP B C   1 
ATOM   6012  O O   . ASP B 1 227 ? -45.484  -39.404 75.015  1.00 69.31  ? 287 ASP B O   1 
ATOM   6013  C CB  . ASP B 1 227 ? -44.165  -38.152 77.528  1.00 67.57  ? 287 ASP B CB  1 
ATOM   6014  C CG  . ASP B 1 227 ? -44.683  -36.712 77.583  1.00 67.33  ? 287 ASP B CG  1 
ATOM   6015  O OD1 . ASP B 1 227 ? -45.833  -36.459 77.167  1.00 78.88  ? 287 ASP B OD1 1 
ATOM   6016  O OD2 . ASP B 1 227 ? -43.939  -35.839 78.032  1.00 63.09  ? 287 ASP B OD2 1 
ATOM   6017  N N   . GLU B 1 228 ? -47.301  -38.707 76.198  1.00 66.78  ? 288 GLU B N   1 
ATOM   6018  C CA  . GLU B 1 228 ? -48.260  -38.649 75.065  1.00 70.08  ? 288 GLU B CA  1 
ATOM   6019  C C   . GLU B 1 228 ? -48.065  -37.351 74.266  1.00 66.80  ? 288 GLU B C   1 
ATOM   6020  O O   . GLU B 1 228 ? -48.730  -37.234 73.247  1.00 55.63  ? 288 GLU B O   1 
ATOM   6021  C CB  . GLU B 1 228 ? -49.699  -38.766 75.574  1.00 74.89  ? 288 GLU B CB  1 
ATOM   6022  C CG  . GLU B 1 228 ? -50.190  -37.535 76.322  1.00 78.99  ? 288 GLU B CG  1 
ATOM   6023  C CD  . GLU B 1 228 ? -51.635  -37.579 76.819  1.00 78.92  ? 288 GLU B CD  1 
ATOM   6024  O OE1 . GLU B 1 228 ? -52.356  -38.595 76.576  1.00 79.37  ? 288 GLU B OE1 1 
ATOM   6025  O OE2 . GLU B 1 228 ? -52.047  -36.578 77.448  1.00 73.83  ? 288 GLU B OE2 1 
ATOM   6026  N N   . PHE B 1 229 ? -47.206  -36.416 74.686  1.00 63.45  ? 289 PHE B N   1 
ATOM   6027  C CA  . PHE B 1 229 ? -46.872  -35.186 73.900  1.00 65.66  ? 289 PHE B CA  1 
ATOM   6028  C C   . PHE B 1 229 ? -45.504  -35.277 73.210  1.00 62.97  ? 289 PHE B C   1 
ATOM   6029  O O   . PHE B 1 229 ? -45.091  -34.277 72.566  1.00 54.62  ? 289 PHE B O   1 
ATOM   6030  C CB  . PHE B 1 229 ? -46.923  -33.931 74.773  1.00 62.55  ? 289 PHE B CB  1 
ATOM   6031  C CG  . PHE B 1 229 ? -48.301  -33.669 75.302  1.00 73.25  ? 289 PHE B CG  1 
ATOM   6032  C CD1 . PHE B 1 229 ? -49.388  -33.736 74.442  1.00 70.49  ? 289 PHE B CD1 1 
ATOM   6033  C CD2 . PHE B 1 229 ? -48.524  -33.423 76.649  1.00 84.06  ? 289 PHE B CD2 1 
ATOM   6034  C CE1 . PHE B 1 229 ? -50.671  -33.512 74.906  1.00 69.87  ? 289 PHE B CE1 1 
ATOM   6035  C CE2 . PHE B 1 229 ? -49.815  -33.233 77.117  1.00 84.45  ? 289 PHE B CE2 1 
ATOM   6036  C CZ  . PHE B 1 229 ? -50.880  -33.258 76.241  1.00 81.04  ? 289 PHE B CZ  1 
ATOM   6037  N N   . TYR B 1 230 ? -44.817  -36.418 73.308  1.00 58.76  ? 290 TYR B N   1 
ATOM   6038  C CA  . TYR B 1 230 ? -43.495  -36.585 72.655  1.00 62.42  ? 290 TYR B CA  1 
ATOM   6039  C C   . TYR B 1 230 ? -43.781  -36.494 71.161  1.00 60.67  ? 290 TYR B C   1 
ATOM   6040  O O   . TYR B 1 230 ? -44.740  -37.131 70.697  1.00 62.10  ? 290 TYR B O   1 
ATOM   6041  C CB  . TYR B 1 230 ? -42.749  -37.856 73.087  1.00 60.73  ? 290 TYR B CB  1 
ATOM   6042  C CG  . TYR B 1 230 ? -41.455  -38.152 72.357  1.00 50.93  ? 290 TYR B CG  1 
ATOM   6043  C CD1 . TYR B 1 230 ? -40.368  -37.306 72.417  1.00 46.46  ? 290 TYR B CD1 1 
ATOM   6044  C CD2 . TYR B 1 230 ? -41.320  -39.317 71.610  1.00 52.11  ? 290 TYR B CD2 1 
ATOM   6045  C CE1 . TYR B 1 230 ? -39.193  -37.595 71.728  1.00 59.19  ? 290 TYR B CE1 1 
ATOM   6046  C CE2 . TYR B 1 230 ? -40.159  -39.629 70.926  1.00 50.30  ? 290 TYR B CE2 1 
ATOM   6047  C CZ  . TYR B 1 230 ? -39.083  -38.765 70.975  1.00 57.80  ? 290 TYR B CZ  1 
ATOM   6048  O OH  . TYR B 1 230 ? -37.952  -39.108 70.260  1.00 61.98  ? 290 TYR B OH  1 
ATOM   6049  N N   . ILE B 1 231 ? -42.980  -35.685 70.468  1.00 57.12  ? 291 ILE B N   1 
ATOM   6050  C CA  . ILE B 1 231 ? -43.169  -35.312 69.038  1.00 51.62  ? 291 ILE B CA  1 
ATOM   6051  C C   . ILE B 1 231 ? -42.364  -36.255 68.152  1.00 45.58  ? 291 ILE B C   1 
ATOM   6052  O O   . ILE B 1 231 ? -42.464  -36.090 66.954  1.00 55.02  ? 291 ILE B O   1 
ATOM   6053  C CB  . ILE B 1 231 ? -42.777  -33.843 68.788  1.00 52.07  ? 291 ILE B CB  1 
ATOM   6054  C CG1 . ILE B 1 231 ? -41.270  -33.636 68.965  1.00 54.37  ? 291 ILE B CG1 1 
ATOM   6055  C CG2 . ILE B 1 231 ? -43.601  -32.920 69.670  1.00 50.81  ? 291 ILE B CG2 1 
ATOM   6056  C CD1 . ILE B 1 231 ? -40.834  -32.199 68.932  1.00 60.99  ? 291 ILE B CD1 1 
ATOM   6057  N N   . GLY B 1 232 ? -41.588  -37.186 68.705  1.00 47.01  ? 292 GLY B N   1 
ATOM   6058  C CA  . GLY B 1 232 ? -40.749  -38.100 67.893  1.00 50.63  ? 292 GLY B CA  1 
ATOM   6059  C C   . GLY B 1 232 ? -41.364  -39.470 67.652  1.00 43.42  ? 292 GLY B C   1 
ATOM   6060  O O   . GLY B 1 232 ? -42.470  -39.723 68.136  1.00 45.09  ? 292 GLY B O   1 
ATOM   6061  N N   . LEU B 1 233 ? -40.628  -40.335 66.957  1.00 46.66  ? 293 LEU B N   1 
ATOM   6062  C CA  . LEU B 1 233 ? -40.966  -41.764 66.749  1.00 52.87  ? 293 LEU B CA  1 
ATOM   6063  C C   . LEU B 1 233 ? -41.000  -42.447 68.107  1.00 51.62  ? 293 LEU B C   1 
ATOM   6064  O O   . LEU B 1 233 ? -39.972  -42.354 68.792  1.00 54.68  ? 293 LEU B O   1 
ATOM   6065  C CB  . LEU B 1 233 ? -39.894  -42.430 65.880  1.00 57.41  ? 293 LEU B CB  1 
ATOM   6066  C CG  . LEU B 1 233 ? -39.555  -41.772 64.542  1.00 61.27  ? 293 LEU B CG  1 
ATOM   6067  C CD1 . LEU B 1 233 ? -38.358  -42.463 63.920  1.00 66.68  ? 293 LEU B CD1 1 
ATOM   6068  C CD2 . LEU B 1 233 ? -40.716  -41.781 63.562  1.00 66.13  ? 293 LEU B CD2 1 
ATOM   6069  N N   . ARG B 1 234 ? -42.115  -43.102 68.463  1.00 55.63  ? 294 ARG B N   1 
ATOM   6070  C CA  . ARG B 1 234 ? -42.225  -43.927 69.702  1.00 62.76  ? 294 ARG B CA  1 
ATOM   6071  C C   . ARG B 1 234 ? -41.457  -45.248 69.536  1.00 59.17  ? 294 ARG B C   1 
ATOM   6072  O O   . ARG B 1 234 ? -42.117  -46.293 69.553  1.00 57.32  ? 294 ARG B O   1 
ATOM   6073  C CB  . ARG B 1 234 ? -43.688  -44.209 70.067  1.00 66.04  ? 294 ARG B CB  1 
ATOM   6074  C CG  . ARG B 1 234 ? -44.320  -43.069 70.850  1.00 71.47  ? 294 ARG B CG  1 
ATOM   6075  C CD  . ARG B 1 234 ? -45.803  -43.183 71.144  1.00 79.75  ? 294 ARG B CD  1 
ATOM   6076  N NE  . ARG B 1 234 ? -46.315  -41.837 71.364  1.00 79.71  ? 294 ARG B NE  1 
ATOM   6077  C CZ  . ARG B 1 234 ? -45.950  -41.067 72.383  1.00 78.45  ? 294 ARG B CZ  1 
ATOM   6078  N NH1 . ARG B 1 234 ? -45.112  -41.517 73.303  1.00 83.74  ? 294 ARG B NH1 1 
ATOM   6079  N NH2 . ARG B 1 234 ? -46.434  -39.851 72.526  1.00 77.07  ? 294 ARG B NH2 1 
ATOM   6080  N N   . GLN B 1 235 ? -40.126  -45.191 69.423  1.00 56.92  ? 295 GLN B N   1 
ATOM   6081  C CA  . GLN B 1 235 ? -39.254  -46.391 69.346  1.00 61.77  ? 295 GLN B CA  1 
ATOM   6082  C C   . GLN B 1 235 ? -37.882  -46.062 69.924  1.00 65.44  ? 295 GLN B C   1 
ATOM   6083  O O   . GLN B 1 235 ? -37.525  -44.857 69.961  1.00 69.96  ? 295 GLN B O   1 
ATOM   6084  C CB  . GLN B 1 235 ? -39.115  -46.867 67.905  1.00 63.50  ? 295 GLN B CB  1 
ATOM   6085  C CG  . GLN B 1 235 ? -38.624  -45.797 66.951  1.00 60.70  ? 295 GLN B CG  1 
ATOM   6086  C CD  . GLN B 1 235 ? -38.098  -46.392 65.660  1.00 61.96  ? 295 GLN B CD  1 
ATOM   6087  O OE1 . GLN B 1 235 ? -38.793  -46.417 64.638  1.00 58.40  ? 295 GLN B OE1 1 
ATOM   6088  N NE2 . GLN B 1 235 ? -36.847  -46.840 65.683  1.00 51.21  ? 295 GLN B NE2 1 
ATOM   6089  N N   . LYS B 1 236 ? -37.151  -47.094 70.365  1.00 61.05  ? 296 LYS B N   1 
ATOM   6090  C CA  . LYS B 1 236 ? -35.801  -46.912 70.945  1.00 62.58  ? 296 LYS B CA  1 
ATOM   6091  C C   . LYS B 1 236 ? -34.838  -46.680 69.781  1.00 56.56  ? 296 LYS B C   1 
ATOM   6092  O O   . LYS B 1 236 ? -35.215  -46.962 68.650  1.00 55.90  ? 296 LYS B O   1 
ATOM   6093  C CB  . LYS B 1 236 ? -35.497  -48.066 71.886  1.00 66.73  ? 296 LYS B CB  1 
ATOM   6094  C CG  . LYS B 1 236 ? -36.116  -49.370 71.425  1.00 82.84  ? 296 LYS B CG  1 
ATOM   6095  C CD  . LYS B 1 236 ? -35.721  -50.504 72.320  1.00 104.91 ? 296 LYS B CD  1 
ATOM   6096  C CE  . LYS B 1 236 ? -35.811  -51.872 71.677  1.00 104.41 ? 296 LYS B CE  1 
ATOM   6097  N NZ  . LYS B 1 236 ? -35.253  -52.898 72.589  1.00 106.03 ? 296 LYS B NZ  1 
ATOM   6098  N N   . ARG B 1 237 ? -33.679  -46.062 70.031  1.00 69.43  ? 297 ARG B N   1 
ATOM   6099  C CA  . ARG B 1 237 ? -32.745  -45.590 68.966  1.00 70.28  ? 297 ARG B CA  1 
ATOM   6100  C C   . ARG B 1 237 ? -32.320  -46.766 68.096  1.00 68.01  ? 297 ARG B C   1 
ATOM   6101  O O   . ARG B 1 237 ? -31.950  -47.816 68.665  1.00 79.70  ? 297 ARG B O   1 
ATOM   6102  C CB  . ARG B 1 237 ? -31.492  -44.927 69.549  1.00 69.43  ? 297 ARG B CB  1 
ATOM   6103  C CG  . ARG B 1 237 ? -31.672  -43.443 69.807  1.00 66.65  ? 297 ARG B CG  1 
ATOM   6104  C CD  . ARG B 1 237 ? -30.433  -42.756 70.328  1.00 62.69  ? 297 ARG B CD  1 
ATOM   6105  N NE  . ARG B 1 237 ? -30.859  -41.446 70.781  1.00 65.62  ? 297 ARG B NE  1 
ATOM   6106  C CZ  . ARG B 1 237 ? -30.969  -40.369 70.011  1.00 62.92  ? 297 ARG B CZ  1 
ATOM   6107  N NH1 . ARG B 1 237 ? -30.636  -40.401 68.728  1.00 68.62  ? 297 ARG B NH1 1 
ATOM   6108  N NH2 . ARG B 1 237 ? -31.394  -39.248 70.544  1.00 56.40  ? 297 ARG B NH2 1 
ATOM   6109  N N   . ALA B 1 238 ? -32.340  -46.566 66.780  1.00 65.99  ? 298 ALA B N   1 
ATOM   6110  C CA  . ALA B 1 238 ? -31.689  -47.448 65.792  1.00 65.15  ? 298 ALA B CA  1 
ATOM   6111  C C   . ALA B 1 238 ? -30.168  -47.382 65.981  1.00 75.13  ? 298 ALA B C   1 
ATOM   6112  O O   . ALA B 1 238 ? -29.616  -46.249 66.174  1.00 58.01  ? 298 ALA B O   1 
ATOM   6113  C CB  . ALA B 1 238 ? -32.089  -47.038 64.404  1.00 67.71  ? 298 ALA B CB  1 
ATOM   6114  N N   . THR B 1 239 ? -29.521  -48.559 65.881  1.00 83.47  ? 299 THR B N   1 
ATOM   6115  C CA  . THR B 1 239 ? -28.065  -48.776 66.100  1.00 81.92  ? 299 THR B CA  1 
ATOM   6116  C C   . THR B 1 239 ? -27.388  -49.236 64.796  1.00 78.58  ? 299 THR B C   1 
ATOM   6117  O O   . THR B 1 239 ? -28.109  -49.611 63.847  1.00 81.40  ? 299 THR B O   1 
ATOM   6118  C CB  . THR B 1 239 ? -27.890  -49.748 67.272  1.00 82.61  ? 299 THR B CB  1 
ATOM   6119  O OG1 . THR B 1 239 ? -28.172  -48.995 68.446  1.00 75.44  ? 299 THR B OG1 1 
ATOM   6120  C CG2 . THR B 1 239 ? -26.514  -50.371 67.428  1.00 93.91  ? 299 THR B CG2 1 
ATOM   6121  N N   . GLY B 1 240 ? -26.058  -49.155 64.751  1.00 76.69  ? 300 GLY B N   1 
ATOM   6122  C CA  . GLY B 1 240 ? -25.212  -49.706 63.677  1.00 82.19  ? 300 GLY B CA  1 
ATOM   6123  C C   . GLY B 1 240 ? -25.740  -49.422 62.279  1.00 78.95  ? 300 GLY B C   1 
ATOM   6124  O O   . GLY B 1 240 ? -25.975  -48.253 61.962  1.00 87.70  ? 300 GLY B O   1 
ATOM   6125  N N   . GLU B 1 241 ? -25.831  -50.477 61.459  1.00 85.21  ? 301 GLU B N   1 
ATOM   6126  C CA  . GLU B 1 241 ? -26.400  -50.541 60.083  1.00 89.43  ? 301 GLU B CA  1 
ATOM   6127  C C   . GLU B 1 241 ? -27.429  -49.417 59.823  1.00 81.90  ? 301 GLU B C   1 
ATOM   6128  O O   . GLU B 1 241 ? -27.169  -48.468 59.025  1.00 67.03  ? 301 GLU B O   1 
ATOM   6129  C CB  . GLU B 1 241 ? -27.015  -51.950 59.889  1.00 100.05 ? 301 GLU B CB  1 
ATOM   6130  C CG  . GLU B 1 241 ? -27.741  -52.546 61.118  1.00 98.09  ? 301 GLU B CG  1 
ATOM   6131  C CD  . GLU B 1 241 ? -26.981  -53.543 62.000  1.00 97.49  ? 301 GLU B CD  1 
ATOM   6132  O OE1 . GLU B 1 241 ? -26.093  -53.145 62.819  1.00 74.92  ? 301 GLU B OE1 1 
ATOM   6133  O OE2 . GLU B 1 241 ? -27.294  -54.735 61.878  1.00 101.16 ? 301 GLU B OE2 1 
ATOM   6134  N N   . GLU B 1 242 ? -28.577  -49.527 60.489  1.00 76.26  ? 302 GLU B N   1 
ATOM   6135  C CA  . GLU B 1 242 ? -29.788  -48.725 60.191  1.00 73.43  ? 302 GLU B CA  1 
ATOM   6136  C C   . GLU B 1 242 ? -29.477  -47.240 60.442  1.00 65.89  ? 302 GLU B C   1 
ATOM   6137  O O   . GLU B 1 242 ? -29.813  -46.417 59.579  1.00 56.95  ? 302 GLU B O   1 
ATOM   6138  C CB  . GLU B 1 242 ? -30.960  -49.245 61.019  1.00 87.57  ? 302 GLU B CB  1 
ATOM   6139  C CG  . GLU B 1 242 ? -32.317  -48.792 60.500  1.00 94.77  ? 302 GLU B CG  1 
ATOM   6140  C CD  . GLU B 1 242 ? -33.492  -49.044 61.443  1.00 104.27 ? 302 GLU B CD  1 
ATOM   6141  O OE1 . GLU B 1 242 ? -33.367  -49.893 62.387  1.00 83.39  ? 302 GLU B OE1 1 
ATOM   6142  O OE2 . GLU B 1 242 ? -34.543  -48.373 61.251  1.00 114.22 ? 302 GLU B OE2 1 
ATOM   6143  N N   . TYR B 1 243 ? -28.858  -46.912 61.579  1.00 61.30  ? 303 TYR B N   1 
ATOM   6144  C CA  . TYR B 1 243 ? -28.425  -45.537 61.932  1.00 65.19  ? 303 TYR B CA  1 
ATOM   6145  C C   . TYR B 1 243 ? -27.541  -45.006 60.806  1.00 70.81  ? 303 TYR B C   1 
ATOM   6146  O O   . TYR B 1 243 ? -27.875  -43.958 60.185  1.00 82.47  ? 303 TYR B O   1 
ATOM   6147  C CB  . TYR B 1 243 ? -27.681  -45.514 63.274  1.00 64.87  ? 303 TYR B CB  1 
ATOM   6148  C CG  . TYR B 1 243 ? -27.180  -44.154 63.704  1.00 61.89  ? 303 TYR B CG  1 
ATOM   6149  C CD1 . TYR B 1 243 ? -28.006  -43.242 64.340  1.00 66.27  ? 303 TYR B CD1 1 
ATOM   6150  C CD2 . TYR B 1 243 ? -25.881  -43.760 63.459  1.00 57.58  ? 303 TYR B CD2 1 
ATOM   6151  C CE1 . TYR B 1 243 ? -27.560  -41.982 64.717  1.00 59.33  ? 303 TYR B CE1 1 
ATOM   6152  C CE2 . TYR B 1 243 ? -25.421  -42.504 63.815  1.00 60.85  ? 303 TYR B CE2 1 
ATOM   6153  C CZ  . TYR B 1 243 ? -26.245  -41.616 64.485  1.00 60.98  ? 303 TYR B CZ  1 
ATOM   6154  O OH  . TYR B 1 243 ? -25.773  -40.385 64.876  1.00 57.01  ? 303 TYR B OH  1 
ATOM   6155  N N   . ASP B 1 244 ? -26.456  -45.728 60.530  1.00 76.59  ? 304 ASP B N   1 
ATOM   6156  C CA  . ASP B 1 244 ? -25.355  -45.264 59.647  1.00 79.19  ? 304 ASP B CA  1 
ATOM   6157  C C   . ASP B 1 244 ? -25.919  -44.815 58.298  1.00 76.80  ? 304 ASP B C   1 
ATOM   6158  O O   . ASP B 1 244 ? -25.524  -43.729 57.828  1.00 67.78  ? 304 ASP B O   1 
ATOM   6159  C CB  . ASP B 1 244 ? -24.290  -46.348 59.476  1.00 77.76  ? 304 ASP B CB  1 
ATOM   6160  C CG  . ASP B 1 244 ? -23.409  -46.551 60.698  1.00 82.75  ? 304 ASP B CG  1 
ATOM   6161  O OD1 . ASP B 1 244 ? -23.154  -45.568 61.408  1.00 80.47  ? 304 ASP B OD1 1 
ATOM   6162  O OD2 . ASP B 1 244 ? -22.957  -47.688 60.912  1.00 92.56  ? 304 ASP B OD2 1 
ATOM   6163  N N   . GLU B 1 245 ? -26.794  -45.638 57.707  1.00 76.49  ? 305 GLU B N   1 
ATOM   6164  C CA  . GLU B 1 245 ? -27.417  -45.422 56.376  1.00 77.23  ? 305 GLU B CA  1 
ATOM   6165  C C   . GLU B 1 245 ? -28.079  -44.050 56.299  1.00 63.40  ? 305 GLU B C   1 
ATOM   6166  O O   . GLU B 1 245 ? -27.877  -43.338 55.303  1.00 51.16  ? 305 GLU B O   1 
ATOM   6167  C CB  . GLU B 1 245 ? -28.515  -46.451 56.127  1.00 87.15  ? 305 GLU B CB  1 
ATOM   6168  C CG  . GLU B 1 245 ? -27.996  -47.797 55.689  1.00 93.25  ? 305 GLU B CG  1 
ATOM   6169  C CD  . GLU B 1 245 ? -29.096  -48.654 55.088  1.00 107.45 ? 305 GLU B CD  1 
ATOM   6170  O OE1 . GLU B 1 245 ? -30.263  -48.544 55.562  1.00 109.19 ? 305 GLU B OE1 1 
ATOM   6171  O OE2 . GLU B 1 245 ? -28.797  -49.401 54.126  1.00 106.40 ? 305 GLU B OE2 1 
ATOM   6172  N N   . LEU B 1 246 ? -28.878  -43.726 57.312  1.00 62.24  ? 306 LEU B N   1 
ATOM   6173  C CA  . LEU B 1 246 ? -29.601  -42.439 57.355  1.00 65.47  ? 306 LEU B CA  1 
ATOM   6174  C C   . LEU B 1 246 ? -28.556  -41.326 57.342  1.00 54.57  ? 306 LEU B C   1 
ATOM   6175  O O   . LEU B 1 246 ? -28.671  -40.400 56.523  1.00 44.88  ? 306 LEU B O   1 
ATOM   6176  C CB  . LEU B 1 246 ? -30.500  -42.374 58.589  1.00 72.54  ? 306 LEU B CB  1 
ATOM   6177  C CG  . LEU B 1 246 ? -31.484  -41.200 58.577  1.00 75.64  ? 306 LEU B CG  1 
ATOM   6178  C CD1 . LEU B 1 246 ? -32.497  -41.349 57.449  1.00 72.56  ? 306 LEU B CD1 1 
ATOM   6179  C CD2 . LEU B 1 246 ? -32.210  -41.076 59.908  1.00 73.98  ? 306 LEU B CD2 1 
ATOM   6180  N N   . ILE B 1 247 ? -27.536  -41.447 58.177  1.00 61.12  ? 307 ILE B N   1 
ATOM   6181  C CA  . ILE B 1 247 ? -26.520  -40.365 58.311  1.00 71.80  ? 307 ILE B CA  1 
ATOM   6182  C C   . ILE B 1 247 ? -25.834  -40.158 56.952  1.00 71.70  ? 307 ILE B C   1 
ATOM   6183  O O   . ILE B 1 247 ? -25.738  -39.002 56.492  1.00 80.44  ? 307 ILE B O   1 
ATOM   6184  C CB  . ILE B 1 247 ? -25.507  -40.664 59.421  1.00 68.22  ? 307 ILE B CB  1 
ATOM   6185  C CG1 . ILE B 1 247 ? -26.179  -40.882 60.778  1.00 79.55  ? 307 ILE B CG1 1 
ATOM   6186  C CG2 . ILE B 1 247 ? -24.490  -39.543 59.476  1.00 65.46  ? 307 ILE B CG2 1 
ATOM   6187  C CD1 . ILE B 1 247 ? -26.737  -39.626 61.404  1.00 87.28  ? 307 ILE B CD1 1 
ATOM   6188  N N   . GLU B 1 248 ? -25.368  -41.229 56.315  1.00 81.37  ? 308 GLU B N   1 
ATOM   6189  C CA  . GLU B 1 248 ? -24.497  -41.078 55.122  1.00 92.17  ? 308 GLU B CA  1 
ATOM   6190  C C   . GLU B 1 248 ? -25.375  -40.674 53.938  1.00 77.89  ? 308 GLU B C   1 
ATOM   6191  O O   . GLU B 1 248 ? -24.855  -40.024 53.014  1.00 73.47  ? 308 GLU B O   1 
ATOM   6192  C CB  . GLU B 1 248 ? -23.565  -42.287 54.976  1.00 99.39  ? 308 GLU B CB  1 
ATOM   6193  C CG  . GLU B 1 248 ? -24.116  -43.510 54.277  1.00 106.98 ? 308 GLU B CG  1 
ATOM   6194  C CD  . GLU B 1 248 ? -23.202  -44.724 54.496  1.00 114.66 ? 308 GLU B CD  1 
ATOM   6195  O OE1 . GLU B 1 248 ? -22.004  -44.663 54.077  1.00 134.36 ? 308 GLU B OE1 1 
ATOM   6196  O OE2 . GLU B 1 248 ? -23.659  -45.712 55.124  1.00 98.36  ? 308 GLU B OE2 1 
ATOM   6197  N N   . GLU B 1 249 ? -26.673  -40.946 54.021  1.00 74.42  ? 309 GLU B N   1 
ATOM   6198  C CA  . GLU B 1 249 ? -27.646  -40.471 53.004  1.00 81.86  ? 309 GLU B CA  1 
ATOM   6199  C C   . GLU B 1 249 ? -27.934  -38.983 53.252  1.00 81.21  ? 309 GLU B C   1 
ATOM   6200  O O   . GLU B 1 249 ? -28.039  -38.214 52.252  1.00 68.12  ? 309 GLU B O   1 
ATOM   6201  C CB  . GLU B 1 249 ? -28.922  -41.306 53.038  1.00 70.32  ? 309 GLU B CB  1 
ATOM   6202  C CG  . GLU B 1 249 ? -29.928  -40.824 52.015  1.00 72.59  ? 309 GLU B CG  1 
ATOM   6203  C CD  . GLU B 1 249 ? -31.360  -41.323 52.204  1.00 77.74  ? 309 GLU B CD  1 
ATOM   6204  O OE1 . GLU B 1 249 ? -31.535  -42.349 52.926  1.00 90.26  ? 309 GLU B OE1 1 
ATOM   6205  O OE2 . GLU B 1 249 ? -32.301  -40.732 51.595  1.00 74.89  ? 309 GLU B OE2 1 
ATOM   6206  N N   . PHE B 1 250 ? -28.042  -38.595 54.533  1.00 73.76  ? 310 PHE B N   1 
ATOM   6207  C CA  . PHE B 1 250 ? -28.187  -37.184 54.974  1.00 64.40  ? 310 PHE B CA  1 
ATOM   6208  C C   . PHE B 1 250 ? -26.991  -36.408 54.423  1.00 61.30  ? 310 PHE B C   1 
ATOM   6209  O O   . PHE B 1 250 ? -27.187  -35.383 53.728  1.00 67.09  ? 310 PHE B O   1 
ATOM   6210  C CB  . PHE B 1 250 ? -28.313  -37.065 56.501  1.00 60.56  ? 310 PHE B CB  1 
ATOM   6211  C CG  . PHE B 1 250 ? -28.228  -35.643 57.008  1.00 61.61  ? 310 PHE B CG  1 
ATOM   6212  C CD1 . PHE B 1 250 ? -29.278  -34.759 56.825  1.00 64.58  ? 310 PHE B CD1 1 
ATOM   6213  C CD2 . PHE B 1 250 ? -27.087  -35.163 57.621  1.00 59.58  ? 310 PHE B CD2 1 
ATOM   6214  C CE1 . PHE B 1 250 ? -29.213  -33.450 57.279  1.00 61.09  ? 310 PHE B CE1 1 
ATOM   6215  C CE2 . PHE B 1 250 ? -26.999  -33.845 58.044  1.00 60.49  ? 310 PHE B CE2 1 
ATOM   6216  C CZ  . PHE B 1 250 ? -28.065  -32.985 57.875  1.00 65.92  ? 310 PHE B CZ  1 
ATOM   6217  N N   . MET B 1 251 ? -25.786  -36.929 54.676  1.00 61.95  ? 311 MET B N   1 
ATOM   6218  C CA  . MET B 1 251 ? -24.502  -36.250 54.357  1.00 69.30  ? 311 MET B CA  1 
ATOM   6219  C C   . MET B 1 251 ? -24.348  -36.176 52.831  1.00 68.33  ? 311 MET B C   1 
ATOM   6220  O O   . MET B 1 251 ? -23.911  -35.110 52.316  1.00 62.25  ? 311 MET B O   1 
ATOM   6221  C CB  . MET B 1 251 ? -23.308  -36.969 55.010  1.00 68.97  ? 311 MET B CB  1 
ATOM   6222  C CG  . MET B 1 251 ? -23.080  -36.647 56.509  1.00 63.90  ? 311 MET B CG  1 
ATOM   6223  S SD  . MET B 1 251 ? -23.122  -34.847 56.889  1.00 65.50  ? 311 MET B SD  1 
ATOM   6224  C CE  . MET B 1 251 ? -21.488  -34.510 57.541  1.00 70.61  ? 311 MET B CE  1 
ATOM   6225  N N   . SER B 1 252 ? -24.744  -37.241 52.126  1.00 67.67  ? 312 SER B N   1 
ATOM   6226  C CA  . SER B 1 252 ? -24.876  -37.230 50.649  1.00 71.51  ? 312 SER B CA  1 
ATOM   6227  C C   . SER B 1 252 ? -25.748  -36.042 50.234  1.00 59.27  ? 312 SER B C   1 
ATOM   6228  O O   . SER B 1 252 ? -25.247  -35.132 49.527  1.00 60.08  ? 312 SER B O   1 
ATOM   6229  C CB  . SER B 1 252 ? -25.444  -38.524 50.146  1.00 73.53  ? 312 SER B CB  1 
ATOM   6230  O OG  . SER B 1 252 ? -25.111  -38.693 48.784  1.00 89.57  ? 312 SER B OG  1 
ATOM   6231  N N   . ALA B 1 253 ? -26.991  -36.056 50.710  1.00 51.51  ? 313 ALA B N   1 
ATOM   6232  C CA  . ALA B 1 253 ? -28.101  -35.199 50.250  1.00 51.24  ? 313 ALA B CA  1 
ATOM   6233  C C   . ALA B 1 253 ? -27.778  -33.720 50.480  1.00 52.57  ? 313 ALA B C   1 
ATOM   6234  O O   . ALA B 1 253 ? -28.133  -32.855 49.626  1.00 48.66  ? 313 ALA B O   1 
ATOM   6235  C CB  . ALA B 1 253 ? -29.337  -35.602 50.984  1.00 55.83  ? 313 ALA B CB  1 
ATOM   6236  N N   . VAL B 1 254 ? -27.148  -33.433 51.609  1.00 54.43  ? 314 VAL B N   1 
ATOM   6237  C CA  . VAL B 1 254 ? -26.809  -32.043 52.006  1.00 58.21  ? 314 VAL B CA  1 
ATOM   6238  C C   . VAL B 1 254 ? -25.833  -31.519 50.954  1.00 54.43  ? 314 VAL B C   1 
ATOM   6239  O O   . VAL B 1 254 ? -25.988  -30.359 50.514  1.00 48.88  ? 314 VAL B O   1 
ATOM   6240  C CB  . VAL B 1 254 ? -26.193  -32.028 53.421  1.00 64.85  ? 314 VAL B CB  1 
ATOM   6241  C CG1 . VAL B 1 254 ? -25.670  -30.664 53.791  1.00 73.20  ? 314 VAL B CG1 1 
ATOM   6242  C CG2 . VAL B 1 254 ? -27.166  -32.500 54.483  1.00 66.84  ? 314 VAL B CG2 1 
ATOM   6243  N N   . LYS B 1 255 ? -24.869  -32.370 50.582  1.00 63.73  ? 315 LYS B N   1 
ATOM   6244  C CA  . LYS B 1 255 ? -23.743  -31.975 49.704  1.00 73.93  ? 315 LYS B CA  1 
ATOM   6245  C C   . LYS B 1 255 ? -24.277  -31.688 48.302  1.00 76.24  ? 315 LYS B C   1 
ATOM   6246  O O   . LYS B 1 255 ? -23.846  -30.646 47.743  1.00 59.49  ? 315 LYS B O   1 
ATOM   6247  C CB  . LYS B 1 255 ? -22.588  -32.975 49.660  1.00 85.73  ? 315 LYS B CB  1 
ATOM   6248  C CG  . LYS B 1 255 ? -21.260  -32.279 49.310  1.00 84.90  ? 315 LYS B CG  1 
ATOM   6249  C CD  . LYS B 1 255 ? -20.367  -32.975 48.295  1.00 78.93  ? 315 LYS B CD  1 
ATOM   6250  C CE  . LYS B 1 255 ? -18.969  -33.284 48.799  1.00 82.12  ? 315 LYS B CE  1 
ATOM   6251  N NZ  . LYS B 1 255 ? -18.652  -34.730 48.656  1.00 92.48  ? 315 LYS B NZ  1 
ATOM   6252  N N   . GLN B 1 256 ? -25.172  -32.557 47.781  1.00 71.29  ? 316 GLN B N   1 
ATOM   6253  C CA  . GLN B 1 256 ? -25.767  -32.431 46.422  1.00 66.43  ? 316 GLN B CA  1 
ATOM   6254  C C   . GLN B 1 256 ? -26.576  -31.137 46.373  1.00 59.81  ? 316 GLN B C   1 
ATOM   6255  O O   . GLN B 1 256 ? -26.444  -30.407 45.417  1.00 61.44  ? 316 GLN B O   1 
ATOM   6256  C CB  . GLN B 1 256 ? -26.607  -33.651 46.036  1.00 72.82  ? 316 GLN B CB  1 
ATOM   6257  C CG  . GLN B 1 256 ? -25.753  -34.876 45.716  1.00 97.13  ? 316 GLN B CG  1 
ATOM   6258  C CD  . GLN B 1 256 ? -25.005  -34.805 44.396  1.00 112.36 ? 316 GLN B CD  1 
ATOM   6259  O OE1 . GLN B 1 256 ? -25.559  -35.081 43.330  1.00 105.27 ? 316 GLN B OE1 1 
ATOM   6260  N NE2 . GLN B 1 256 ? -23.719  -34.467 44.453  1.00 101.92 ? 316 GLN B NE2 1 
ATOM   6261  N N   . PHE B 1 257 ? -27.349  -30.841 47.408  1.00 63.95  ? 317 PHE B N   1 
ATOM   6262  C CA  . PHE B 1 257 ? -28.276  -29.684 47.411  1.00 60.06  ? 317 PHE B CA  1 
ATOM   6263  C C   . PHE B 1 257 ? -27.497  -28.380 47.663  1.00 53.26  ? 317 PHE B C   1 
ATOM   6264  O O   . PHE B 1 257 ? -27.648  -27.442 46.859  1.00 55.80  ? 317 PHE B O   1 
ATOM   6265  C CB  . PHE B 1 257 ? -29.448  -29.979 48.352  1.00 68.75  ? 317 PHE B CB  1 
ATOM   6266  C CG  . PHE B 1 257 ? -30.767  -29.387 47.913  1.00 71.20  ? 317 PHE B CG  1 
ATOM   6267  C CD1 . PHE B 1 257 ? -31.272  -29.541 46.631  1.00 74.76  ? 317 PHE B CD1 1 
ATOM   6268  C CD2 . PHE B 1 257 ? -31.469  -28.599 48.783  1.00 73.99  ? 317 PHE B CD2 1 
ATOM   6269  C CE1 . PHE B 1 257 ? -32.451  -28.924 46.245  1.00 71.46  ? 317 PHE B CE1 1 
ATOM   6270  C CE2 . PHE B 1 257 ? -32.663  -28.000 48.410  1.00 82.87  ? 317 PHE B CE2 1 
ATOM   6271  C CZ  . PHE B 1 257 ? -33.153  -28.165 47.140  1.00 73.28  ? 317 PHE B CZ  1 
ATOM   6272  N N   . TYR B 1 258 ? -26.657  -28.317 48.694  1.00 51.86  ? 318 TYR B N   1 
ATOM   6273  C CA  . TYR B 1 258 ? -26.107  -27.037 49.219  1.00 55.54  ? 318 TYR B CA  1 
ATOM   6274  C C   . TYR B 1 258 ? -24.647  -26.844 48.793  1.00 56.20  ? 318 TYR B C   1 
ATOM   6275  O O   . TYR B 1 258 ? -24.125  -25.691 48.910  1.00 52.42  ? 318 TYR B O   1 
ATOM   6276  C CB  . TYR B 1 258 ? -26.330  -26.956 50.736  1.00 59.67  ? 318 TYR B CB  1 
ATOM   6277  C CG  . TYR B 1 258 ? -27.786  -27.038 51.158  1.00 61.48  ? 318 TYR B CG  1 
ATOM   6278  C CD1 . TYR B 1 258 ? -28.745  -26.133 50.697  1.00 53.65  ? 318 TYR B CD1 1 
ATOM   6279  C CD2 . TYR B 1 258 ? -28.198  -28.021 52.045  1.00 54.01  ? 318 TYR B CD2 1 
ATOM   6280  C CE1 . TYR B 1 258 ? -30.064  -26.218 51.106  1.00 57.09  ? 318 TYR B CE1 1 
ATOM   6281  C CE2 . TYR B 1 258 ? -29.513  -28.123 52.454  1.00 57.50  ? 318 TYR B CE2 1 
ATOM   6282  C CZ  . TYR B 1 258 ? -30.461  -27.225 51.984  1.00 65.31  ? 318 TYR B CZ  1 
ATOM   6283  O OH  . TYR B 1 258 ? -31.777  -27.341 52.380  1.00 63.89  ? 318 TYR B OH  1 
ATOM   6284  N N   . GLY B 1 259 ? -24.018  -27.910 48.292  1.00 55.34  ? 319 GLY B N   1 
ATOM   6285  C CA  . GLY B 1 259 ? -22.622  -27.886 47.836  1.00 59.46  ? 319 GLY B CA  1 
ATOM   6286  C C   . GLY B 1 259 ? -21.690  -28.307 48.954  1.00 71.26  ? 319 GLY B C   1 
ATOM   6287  O O   . GLY B 1 259 ? -22.183  -28.843 49.984  1.00 73.95  ? 319 GLY B O   1 
ATOM   6288  N N   . GLU B 1 260 ? -20.379  -28.107 48.771  1.00 76.69  ? 320 GLU B N   1 
ATOM   6289  C CA  . GLU B 1 260 ? -19.366  -28.554 49.755  1.00 74.16  ? 320 GLU B CA  1 
ATOM   6290  C C   . GLU B 1 260 ? -19.035  -27.407 50.729  1.00 61.40  ? 320 GLU B C   1 
ATOM   6291  O O   . GLU B 1 260 ? -18.852  -27.725 51.899  1.00 70.26  ? 320 GLU B O   1 
ATOM   6292  C CB  . GLU B 1 260 ? -18.190  -29.169 49.000  1.00 81.07  ? 320 GLU B CB  1 
ATOM   6293  C CG  . GLU B 1 260 ? -17.234  -29.917 49.914  1.00 84.06  ? 320 GLU B CG  1 
ATOM   6294  C CD  . GLU B 1 260 ? -16.193  -29.046 50.607  1.00 86.40  ? 320 GLU B CD  1 
ATOM   6295  O OE1 . GLU B 1 260 ? -16.187  -27.818 50.326  1.00 77.93  ? 320 GLU B OE1 1 
ATOM   6296  O OE2 . GLU B 1 260 ? -15.390  -29.561 51.433  1.00 88.90  ? 320 GLU B OE2 1 
ATOM   6297  N N   . LYS B 1 261 ? -19.021  -26.143 50.300  1.00 51.04  ? 321 LYS B N   1 
ATOM   6298  C CA  . LYS B 1 261 ? -18.763  -24.968 51.193  1.00 56.09  ? 321 LYS B CA  1 
ATOM   6299  C C   . LYS B 1 261 ? -19.857  -24.746 52.269  1.00 53.36  ? 321 LYS B C   1 
ATOM   6300  O O   . LYS B 1 261 ? -19.774  -23.783 53.047  1.00 58.95  ? 321 LYS B O   1 
ATOM   6301  C CB  . LYS B 1 261 ? -18.523  -23.736 50.317  1.00 59.83  ? 321 LYS B CB  1 
ATOM   6302  C CG  . LYS B 1 261 ? -17.220  -23.807 49.514  1.00 65.06  ? 321 LYS B CG  1 
ATOM   6303  C CD  . LYS B 1 261 ? -17.300  -23.257 48.093  1.00 71.66  ? 321 LYS B CD  1 
ATOM   6304  C CE  . LYS B 1 261 ? -17.772  -21.819 48.043  1.00 77.78  ? 321 LYS B CE  1 
ATOM   6305  N NZ  . LYS B 1 261 ? -16.697  -20.927 47.560  1.00 89.19  ? 321 LYS B NZ  1 
ATOM   6306  N N   . VAL B 1 262 ? -20.856  -25.610 52.385  1.00 58.52  ? 322 VAL B N   1 
ATOM   6307  C CA  . VAL B 1 262 ? -21.864  -25.514 53.484  1.00 56.30  ? 322 VAL B CA  1 
ATOM   6308  C C   . VAL B 1 262 ? -21.272  -26.098 54.770  1.00 57.91  ? 322 VAL B C   1 
ATOM   6309  O O   . VAL B 1 262 ? -20.853  -27.294 54.780  1.00 60.85  ? 322 VAL B O   1 
ATOM   6310  C CB  . VAL B 1 262 ? -23.203  -26.191 53.130  1.00 59.61  ? 322 VAL B CB  1 
ATOM   6311  C CG1 . VAL B 1 262 ? -23.106  -27.718 53.093  1.00 52.46  ? 322 VAL B CG1 1 
ATOM   6312  C CG2 . VAL B 1 262 ? -24.294  -25.741 54.091  1.00 63.06  ? 322 VAL B CG2 1 
ATOM   6313  N N   . LEU B 1 263 ? -21.260  -25.268 55.815  1.00 58.43  ? 323 LEU B N   1 
ATOM   6314  C CA  . LEU B 1 263 ? -20.824  -25.618 57.184  1.00 51.98  ? 323 LEU B CA  1 
ATOM   6315  C C   . LEU B 1 263 ? -21.876  -26.542 57.799  1.00 51.90  ? 323 LEU B C   1 
ATOM   6316  O O   . LEU B 1 263 ? -23.034  -26.174 57.782  1.00 44.64  ? 323 LEU B O   1 
ATOM   6317  C CB  . LEU B 1 263 ? -20.662  -24.327 57.983  1.00 53.38  ? 323 LEU B CB  1 
ATOM   6318  C CG  . LEU B 1 263 ? -20.217  -24.498 59.434  1.00 60.00  ? 323 LEU B CG  1 
ATOM   6319  C CD1 . LEU B 1 263 ? -19.152  -25.585 59.582  1.00 58.01  ? 323 LEU B CD1 1 
ATOM   6320  C CD2 . LEU B 1 263 ? -19.710  -23.158 59.990  1.00 59.80  ? 323 LEU B CD2 1 
ATOM   6321  N N   . ILE B 1 264 ? -21.465  -27.719 58.259  1.00 55.86  ? 324 ILE B N   1 
ATOM   6322  C CA  . ILE B 1 264 ? -22.306  -28.702 58.993  1.00 53.56  ? 324 ILE B CA  1 
ATOM   6323  C C   . ILE B 1 264 ? -21.783  -28.739 60.432  1.00 59.76  ? 324 ILE B C   1 
ATOM   6324  O O   . ILE B 1 264 ? -20.757  -29.428 60.657  1.00 73.59  ? 324 ILE B O   1 
ATOM   6325  C CB  . ILE B 1 264 ? -22.228  -30.109 58.343  1.00 56.94  ? 324 ILE B CB  1 
ATOM   6326  C CG1 . ILE B 1 264 ? -22.488  -30.103 56.844  1.00 56.26  ? 324 ILE B CG1 1 
ATOM   6327  C CG2 . ILE B 1 264 ? -23.128  -31.096 59.068  1.00 57.43  ? 324 ILE B CG2 1 
ATOM   6328  C CD1 . ILE B 1 264 ? -23.713  -29.356 56.510  1.00 67.79  ? 324 ILE B CD1 1 
ATOM   6329  N N   . GLN B 1 265 ? -22.451  -28.043 61.363  1.00 59.00  ? 325 GLN B N   1 
ATOM   6330  C CA  . GLN B 1 265 ? -22.116  -28.015 62.819  1.00 51.85  ? 325 GLN B CA  1 
ATOM   6331  C C   . GLN B 1 265 ? -22.922  -29.095 63.535  1.00 44.96  ? 325 GLN B C   1 
ATOM   6332  O O   . GLN B 1 265 ? -24.129  -28.944 63.654  1.00 48.77  ? 325 GLN B O   1 
ATOM   6333  C CB  . GLN B 1 265 ? -22.377  -26.625 63.391  1.00 54.84  ? 325 GLN B CB  1 
ATOM   6334  C CG  . GLN B 1 265 ? -22.134  -26.493 64.881  1.00 54.87  ? 325 GLN B CG  1 
ATOM   6335  C CD  . GLN B 1 265 ? -22.005  -25.026 65.207  1.00 58.83  ? 325 GLN B CD  1 
ATOM   6336  O OE1 . GLN B 1 265 ? -21.424  -24.262 64.446  1.00 62.05  ? 325 GLN B OE1 1 
ATOM   6337  N NE2 . GLN B 1 265 ? -22.541  -24.612 66.340  1.00 59.96  ? 325 GLN B NE2 1 
ATOM   6338  N N   . PHE B 1 266 ? -22.264  -30.185 63.912  1.00 48.66  ? 326 PHE B N   1 
ATOM   6339  C CA  . PHE B 1 266 ? -22.822  -31.270 64.751  1.00 51.06  ? 326 PHE B CA  1 
ATOM   6340  C C   . PHE B 1 266 ? -22.927  -30.780 66.200  1.00 61.88  ? 326 PHE B C   1 
ATOM   6341  O O   . PHE B 1 266 ? -21.967  -30.116 66.701  1.00 69.20  ? 326 PHE B O   1 
ATOM   6342  C CB  . PHE B 1 266 ? -21.937  -32.504 64.709  1.00 51.95  ? 326 PHE B CB  1 
ATOM   6343  C CG  . PHE B 1 266 ? -21.812  -33.120 63.351  1.00 60.23  ? 326 PHE B CG  1 
ATOM   6344  C CD1 . PHE B 1 266 ? -22.853  -33.869 62.845  1.00 59.43  ? 326 PHE B CD1 1 
ATOM   6345  C CD2 . PHE B 1 266 ? -20.646  -33.005 62.608  1.00 67.70  ? 326 PHE B CD2 1 
ATOM   6346  C CE1 . PHE B 1 266 ? -22.741  -34.479 61.607  1.00 60.61  ? 326 PHE B CE1 1 
ATOM   6347  C CE2 . PHE B 1 266 ? -20.538  -33.616 61.366  1.00 68.64  ? 326 PHE B CE2 1 
ATOM   6348  C CZ  . PHE B 1 266 ? -21.588  -34.352 60.873  1.00 62.71  ? 326 PHE B CZ  1 
ATOM   6349  N N   . GLU B 1 267 ? -24.054  -31.097 66.856  1.00 59.32  ? 327 GLU B N   1 
ATOM   6350  C CA  . GLU B 1 267 ? -24.373  -30.702 68.254  1.00 57.12  ? 327 GLU B CA  1 
ATOM   6351  C C   . GLU B 1 267 ? -24.876  -31.934 69.008  1.00 56.56  ? 327 GLU B C   1 
ATOM   6352  O O   . GLU B 1 267 ? -25.760  -32.649 68.469  1.00 59.97  ? 327 GLU B O   1 
ATOM   6353  C CB  . GLU B 1 267 ? -25.446  -29.612 68.289  1.00 60.63  ? 327 GLU B CB  1 
ATOM   6354  C CG  . GLU B 1 267 ? -24.959  -28.247 67.848  1.00 63.69  ? 327 GLU B CG  1 
ATOM   6355  C CD  . GLU B 1 267 ? -24.048  -27.558 68.856  1.00 70.76  ? 327 GLU B CD  1 
ATOM   6356  O OE1 . GLU B 1 267 ? -23.793  -28.114 69.989  1.00 65.19  ? 327 GLU B OE1 1 
ATOM   6357  O OE2 . GLU B 1 267 ? -23.597  -26.456 68.508  1.00 66.53  ? 327 GLU B OE2 1 
ATOM   6358  N N   . ASP B 1 268 ? -24.302  -32.191 70.177  1.00 52.69  ? 328 ASP B N   1 
ATOM   6359  C CA  . ASP B 1 268 ? -24.893  -33.074 71.206  1.00 61.11  ? 328 ASP B CA  1 
ATOM   6360  C C   . ASP B 1 268 ? -25.142  -34.484 70.646  1.00 61.24  ? 328 ASP B C   1 
ATOM   6361  O O   . ASP B 1 268 ? -26.242  -35.022 70.865  1.00 62.03  ? 328 ASP B O   1 
ATOM   6362  C CB  . ASP B 1 268 ? -26.156  -32.399 71.740  1.00 66.59  ? 328 ASP B CB  1 
ATOM   6363  C CG  . ASP B 1 268 ? -25.907  -31.056 72.413  1.00 66.37  ? 328 ASP B CG  1 
ATOM   6364  O OD1 . ASP B 1 268 ? -24.740  -30.657 72.570  1.00 71.36  ? 328 ASP B OD1 1 
ATOM   6365  O OD2 . ASP B 1 268 ? -26.905  -30.409 72.767  1.00 85.52  ? 328 ASP B OD2 1 
ATOM   6366  N N   . PHE B 1 269 ? -24.160  -35.075 69.972  1.00 60.22  ? 329 PHE B N   1 
ATOM   6367  C CA  . PHE B 1 269 ? -24.127  -36.535 69.704  1.00 64.16  ? 329 PHE B CA  1 
ATOM   6368  C C   . PHE B 1 269 ? -23.354  -37.194 70.855  1.00 72.52  ? 329 PHE B C   1 
ATOM   6369  O O   . PHE B 1 269 ? -22.646  -36.441 71.577  1.00 71.03  ? 329 PHE B O   1 
ATOM   6370  C CB  . PHE B 1 269 ? -23.449  -36.829 68.368  1.00 69.27  ? 329 PHE B CB  1 
ATOM   6371  C CG  . PHE B 1 269 ? -24.220  -36.409 67.138  1.00 72.07  ? 329 PHE B CG  1 
ATOM   6372  C CD1 . PHE B 1 269 ? -24.312  -35.070 66.774  1.00 66.54  ? 329 PHE B CD1 1 
ATOM   6373  C CD2 . PHE B 1 269 ? -24.796  -37.370 66.300  1.00 75.39  ? 329 PHE B CD2 1 
ATOM   6374  C CE1 . PHE B 1 269 ? -25.005  -34.703 65.632  1.00 67.32  ? 329 PHE B CE1 1 
ATOM   6375  C CE2 . PHE B 1 269 ? -25.492  -37.001 65.157  1.00 68.20  ? 329 PHE B CE2 1 
ATOM   6376  C CZ  . PHE B 1 269 ? -25.602  -35.664 64.835  1.00 68.88  ? 329 PHE B CZ  1 
ATOM   6377  N N   . ALA B 1 270 ? -23.468  -38.524 71.011  1.00 76.02  ? 330 ALA B N   1 
ATOM   6378  C CA  . ALA B 1 270 ? -22.677  -39.359 71.954  1.00 83.52  ? 330 ALA B CA  1 
ATOM   6379  C C   . ALA B 1 270 ? -21.214  -39.366 71.504  1.00 83.55  ? 330 ALA B C   1 
ATOM   6380  O O   . ALA B 1 270 ? -20.991  -39.086 70.316  1.00 89.18  ? 330 ALA B O   1 
ATOM   6381  C CB  . ALA B 1 270 ? -23.234  -40.767 72.006  1.00 83.38  ? 330 ALA B CB  1 
ATOM   6382  N N   . ASN B 1 271 ? -20.281  -39.723 72.389  1.00 91.70  ? 331 ASN B N   1 
ATOM   6383  C CA  . ASN B 1 271 ? -18.830  -39.825 72.055  1.00 95.07  ? 331 ASN B CA  1 
ATOM   6384  C C   . ASN B 1 271 ? -18.679  -40.677 70.790  1.00 79.87  ? 331 ASN B C   1 
ATOM   6385  O O   . ASN B 1 271 ? -18.336  -40.152 69.731  1.00 82.79  ? 331 ASN B O   1 
ATOM   6386  C CB  . ASN B 1 271 ? -17.971  -40.341 73.222  1.00 99.26  ? 331 ASN B CB  1 
ATOM   6387  C CG  . ASN B 1 271 ? -18.170  -39.575 74.516  1.00 112.11 ? 331 ASN B CG  1 
ATOM   6388  O OD1 . ASN B 1 271 ? -18.763  -38.490 74.550  1.00 122.72 ? 331 ASN B OD1 1 
ATOM   6389  N ND2 . ASN B 1 271 ? -17.679  -40.148 75.600  1.00 123.74 ? 331 ASN B ND2 1 
ATOM   6390  N N   . HIS B 1 272 ? -18.932  -41.968 70.904  1.00 79.58  ? 332 HIS B N   1 
ATOM   6391  C CA  . HIS B 1 272 ? -18.793  -42.985 69.834  1.00 87.90  ? 332 HIS B CA  1 
ATOM   6392  C C   . HIS B 1 272 ? -19.078  -42.309 68.470  1.00 74.21  ? 332 HIS B C   1 
ATOM   6393  O O   . HIS B 1 272 ? -18.153  -42.171 67.630  1.00 80.30  ? 332 HIS B O   1 
ATOM   6394  C CB  . HIS B 1 272 ? -19.654  -44.209 70.247  1.00 109.81 ? 332 HIS B CB  1 
ATOM   6395  C CG  . HIS B 1 272 ? -19.962  -44.271 71.725  1.00 124.00 ? 332 HIS B CG  1 
ATOM   6396  N ND1 . HIS B 1 272 ? -20.831  -43.363 72.358  1.00 109.34 ? 332 HIS B ND1 1 
ATOM   6397  C CD2 . HIS B 1 272 ? -19.515  -45.095 72.707  1.00 107.82 ? 332 HIS B CD2 1 
ATOM   6398  C CE1 . HIS B 1 272 ? -20.904  -43.634 73.648  1.00 92.09  ? 332 HIS B CE1 1 
ATOM   6399  N NE2 . HIS B 1 272 ? -20.113  -44.700 73.884  1.00 105.63 ? 332 HIS B NE2 1 
ATOM   6400  N N   . ASN B 1 273 ? -20.296  -41.821 68.279  1.00 74.44  ? 333 ASN B N   1 
ATOM   6401  C CA  . ASN B 1 273 ? -20.758  -41.265 66.974  1.00 78.55  ? 333 ASN B CA  1 
ATOM   6402  C C   . ASN B 1 273 ? -20.030  -39.948 66.642  1.00 85.95  ? 333 ASN B C   1 
ATOM   6403  O O   . ASN B 1 273 ? -19.489  -39.862 65.524  1.00 85.55  ? 333 ASN B O   1 
ATOM   6404  C CB  . ASN B 1 273 ? -22.283  -41.133 66.896  1.00 74.16  ? 333 ASN B CB  1 
ATOM   6405  C CG  . ASN B 1 273 ? -22.976  -42.462 66.660  1.00 73.06  ? 333 ASN B CG  1 
ATOM   6406  O OD1 . ASN B 1 273 ? -22.349  -43.440 66.270  1.00 85.73  ? 333 ASN B OD1 1 
ATOM   6407  N ND2 . ASN B 1 273 ? -24.270  -42.542 66.904  1.00 68.34  ? 333 ASN B ND2 1 
ATOM   6408  N N   . ALA B 1 274 ? -20.026  -38.954 67.541  1.00 81.73  ? 334 ALA B N   1 
ATOM   6409  C CA  . ALA B 1 274 ? -19.514  -37.576 67.278  1.00 80.20  ? 334 ALA B CA  1 
ATOM   6410  C C   . ALA B 1 274 ? -18.115  -37.608 66.662  1.00 79.84  ? 334 ALA B C   1 
ATOM   6411  O O   . ALA B 1 274 ? -17.815  -36.639 65.929  1.00 76.67  ? 334 ALA B O   1 
ATOM   6412  C CB  . ALA B 1 274 ? -19.466  -36.752 68.539  1.00 79.55  ? 334 ALA B CB  1 
ATOM   6413  N N   . PHE B 1 275 ? -17.318  -38.648 66.983  1.00 78.55  ? 335 PHE B N   1 
ATOM   6414  C CA  . PHE B 1 275 ? -15.939  -38.887 66.479  1.00 85.04  ? 335 PHE B CA  1 
ATOM   6415  C C   . PHE B 1 275 ? -15.981  -39.496 65.062  1.00 90.54  ? 335 PHE B C   1 
ATOM   6416  O O   . PHE B 1 275 ? -15.359  -38.881 64.165  1.00 112.76 ? 335 PHE B O   1 
ATOM   6417  C CB  . PHE B 1 275 ? -15.097  -39.684 67.489  1.00 83.47  ? 335 PHE B CB  1 
ATOM   6418  C CG  . PHE B 1 275 ? -14.618  -38.889 68.689  1.00 79.30  ? 335 PHE B CG  1 
ATOM   6419  C CD1 . PHE B 1 275 ? -13.951  -37.675 68.536  1.00 80.11  ? 335 PHE B CD1 1 
ATOM   6420  C CD2 . PHE B 1 275 ? -14.815  -39.350 69.984  1.00 84.35  ? 335 PHE B CD2 1 
ATOM   6421  C CE1 . PHE B 1 275 ? -13.517  -36.937 69.635  1.00 69.65  ? 335 PHE B CE1 1 
ATOM   6422  C CE2 . PHE B 1 275 ? -14.389  -38.606 71.083  1.00 86.80  ? 335 PHE B CE2 1 
ATOM   6423  C CZ  . PHE B 1 275 ? -13.743  -37.396 70.911  1.00 73.70  ? 335 PHE B CZ  1 
ATOM   6424  N N   . ASP B 1 276 ? -16.700  -40.600 64.820  1.00 79.26  ? 336 ASP B N   1 
ATOM   6425  C CA  . ASP B 1 276 ? -16.776  -41.203 63.454  1.00 80.32  ? 336 ASP B CA  1 
ATOM   6426  C C   . ASP B 1 276 ? -17.250  -40.157 62.439  1.00 72.96  ? 336 ASP B C   1 
ATOM   6427  O O   . ASP B 1 276 ? -16.828  -40.267 61.284  1.00 80.61  ? 336 ASP B O   1 
ATOM   6428  C CB  . ASP B 1 276 ? -17.699  -42.418 63.341  1.00 82.46  ? 336 ASP B CB  1 
ATOM   6429  C CG  . ASP B 1 276 ? -17.453  -43.450 64.420  1.00 91.99  ? 336 ASP B CG  1 
ATOM   6430  O OD1 . ASP B 1 276 ? -16.964  -43.060 65.493  1.00 93.55  ? 336 ASP B OD1 1 
ATOM   6431  O OD2 . ASP B 1 276 ? -17.737  -44.630 64.167  1.00 91.83  ? 336 ASP B OD2 1 
ATOM   6432  N N   . LEU B 1 277 ? -18.107  -39.213 62.839  1.00 70.48  ? 337 LEU B N   1 
ATOM   6433  C CA  . LEU B 1 277 ? -18.659  -38.164 61.939  1.00 76.94  ? 337 LEU B CA  1 
ATOM   6434  C C   . LEU B 1 277 ? -17.565  -37.148 61.588  1.00 73.89  ? 337 LEU B C   1 
ATOM   6435  O O   . LEU B 1 277 ? -17.517  -36.712 60.428  1.00 81.45  ? 337 LEU B O   1 
ATOM   6436  C CB  . LEU B 1 277 ? -19.875  -37.485 62.583  1.00 86.87  ? 337 LEU B CB  1 
ATOM   6437  C CG  . LEU B 1 277 ? -21.098  -38.382 62.803  1.00 87.90  ? 337 LEU B CG  1 
ATOM   6438  C CD1 . LEU B 1 277 ? -22.293  -37.568 63.295  1.00 86.16  ? 337 LEU B CD1 1 
ATOM   6439  C CD2 . LEU B 1 277 ? -21.480  -39.172 61.555  1.00 86.38  ? 337 LEU B CD2 1 
ATOM   6440  N N   . LEU B 1 278 ? -16.707  -36.786 62.535  1.00 71.55  ? 338 LEU B N   1 
ATOM   6441  C CA  . LEU B 1 278 ? -15.562  -35.873 62.270  1.00 69.94  ? 338 LEU B CA  1 
ATOM   6442  C C   . LEU B 1 278 ? -14.469  -36.613 61.473  1.00 76.06  ? 338 LEU B C   1 
ATOM   6443  O O   . LEU B 1 278 ? -13.828  -35.963 60.596  1.00 73.62  ? 338 LEU B O   1 
ATOM   6444  C CB  . LEU B 1 278 ? -15.030  -35.313 63.593  1.00 71.76  ? 338 LEU B CB  1 
ATOM   6445  C CG  . LEU B 1 278 ? -15.602  -33.958 64.019  1.00 79.26  ? 338 LEU B CG  1 
ATOM   6446  C CD1 . LEU B 1 278 ? -14.927  -33.467 65.282  1.00 82.86  ? 338 LEU B CD1 1 
ATOM   6447  C CD2 . LEU B 1 278 ? -15.454  -32.902 62.934  1.00 88.19  ? 338 LEU B CD2 1 
ATOM   6448  N N   . GLU B 1 279 ? -14.301  -37.922 61.724  1.00 81.60  ? 339 GLU B N   1 
ATOM   6449  C CA  . GLU B 1 279 ? -13.331  -38.805 61.018  1.00 77.15  ? 339 GLU B CA  1 
ATOM   6450  C C   . GLU B 1 279 ? -13.743  -38.968 59.553  1.00 79.02  ? 339 GLU B C   1 
ATOM   6451  O O   . GLU B 1 279 ? -13.005  -38.462 58.680  1.00 91.79  ? 339 GLU B O   1 
ATOM   6452  C CB  . GLU B 1 279 ? -13.250  -40.169 61.692  1.00 90.10  ? 339 GLU B CB  1 
ATOM   6453  C CG  . GLU B 1 279 ? -11.884  -40.429 62.312  1.00 100.90 ? 339 GLU B CG  1 
ATOM   6454  C CD  . GLU B 1 279 ? -11.716  -41.831 62.872  1.00 114.31 ? 339 GLU B CD  1 
ATOM   6455  O OE1 . GLU B 1 279 ? -12.161  -42.806 62.207  1.00 101.04 ? 339 GLU B OE1 1 
ATOM   6456  O OE2 . GLU B 1 279 ? -11.142  -41.954 63.986  1.00 137.28 ? 339 GLU B OE2 1 
ATOM   6457  N N   . LYS B 1 280 ? -14.891  -39.607 59.298  1.00 76.14  ? 340 LYS B N   1 
ATOM   6458  C CA  . LYS B 1 280 ? -15.389  -39.961 57.936  1.00 76.56  ? 340 LYS B CA  1 
ATOM   6459  C C   . LYS B 1 280 ? -15.608  -38.724 57.044  1.00 73.41  ? 340 LYS B C   1 
ATOM   6460  O O   . LYS B 1 280 ? -15.291  -38.828 55.855  1.00 79.29  ? 340 LYS B O   1 
ATOM   6461  C CB  . LYS B 1 280 ? -16.682  -40.767 58.064  1.00 73.57  ? 340 LYS B CB  1 
ATOM   6462  C CG  . LYS B 1 280 ? -17.373  -41.153 56.768  1.00 78.42  ? 340 LYS B CG  1 
ATOM   6463  C CD  . LYS B 1 280 ? -18.287  -42.369 56.969  1.00 87.79  ? 340 LYS B CD  1 
ATOM   6464  C CE  . LYS B 1 280 ? -19.117  -42.768 55.763  1.00 85.78  ? 340 LYS B CE  1 
ATOM   6465  N NZ  . LYS B 1 280 ? -18.448  -42.445 54.476  1.00 84.31  ? 340 LYS B NZ  1 
ATOM   6466  N N   . TYR B 1 281 ? -16.114  -37.595 57.557  1.00 66.26  ? 341 TYR B N   1 
ATOM   6467  C CA  . TYR B 1 281 ? -16.604  -36.485 56.692  1.00 72.26  ? 341 TYR B CA  1 
ATOM   6468  C C   . TYR B 1 281 ? -15.654  -35.276 56.706  1.00 71.86  ? 341 TYR B C   1 
ATOM   6469  O O   . TYR B 1 281 ? -16.064  -34.218 56.185  1.00 76.19  ? 341 TYR B O   1 
ATOM   6470  C CB  . TYR B 1 281 ? -18.058  -36.147 57.053  1.00 72.21  ? 341 TYR B CB  1 
ATOM   6471  C CG  . TYR B 1 281 ? -19.019  -37.292 56.826  1.00 67.46  ? 341 TYR B CG  1 
ATOM   6472  C CD1 . TYR B 1 281 ? -19.434  -37.646 55.557  1.00 68.90  ? 341 TYR B CD1 1 
ATOM   6473  C CD2 . TYR B 1 281 ? -19.471  -38.068 57.877  1.00 60.60  ? 341 TYR B CD2 1 
ATOM   6474  C CE1 . TYR B 1 281 ? -20.276  -38.723 55.344  1.00 65.21  ? 341 TYR B CE1 1 
ATOM   6475  C CE2 . TYR B 1 281 ? -20.312  -39.146 57.685  1.00 52.05  ? 341 TYR B CE2 1 
ATOM   6476  C CZ  . TYR B 1 281 ? -20.723  -39.465 56.413  1.00 54.71  ? 341 TYR B CZ  1 
ATOM   6477  O OH  . TYR B 1 281 ? -21.567  -40.500 56.178  1.00 64.23  ? 341 TYR B OH  1 
ATOM   6478  N N   . SER B 1 282 ? -14.431  -35.420 57.229  1.00 67.23  ? 342 SER B N   1 
ATOM   6479  C CA  . SER B 1 282 ? -13.392  -34.361 57.209  1.00 71.85  ? 342 SER B CA  1 
ATOM   6480  C C   . SER B 1 282 ? -12.952  -34.093 55.769  1.00 83.53  ? 342 SER B C   1 
ATOM   6481  O O   . SER B 1 282 ? -12.692  -32.921 55.445  1.00 87.31  ? 342 SER B O   1 
ATOM   6482  C CB  . SER B 1 282 ? -12.221  -34.732 58.060  1.00 79.77  ? 342 SER B CB  1 
ATOM   6483  O OG  . SER B 1 282 ? -12.582  -34.746 59.434  1.00 90.84  ? 342 SER B OG  1 
ATOM   6484  N N   . LYS B 1 283 ? -12.875  -35.139 54.941  1.00 98.81  ? 343 LYS B N   1 
ATOM   6485  C CA  . LYS B 1 283 ? -12.428  -35.059 53.523  1.00 109.36 ? 343 LYS B CA  1 
ATOM   6486  C C   . LYS B 1 283 ? -13.544  -34.427 52.681  1.00 107.50 ? 343 LYS B C   1 
ATOM   6487  O O   . LYS B 1 283 ? -13.324  -33.347 52.085  1.00 103.71 ? 343 LYS B O   1 
ATOM   6488  C CB  . LYS B 1 283 ? -12.059  -36.447 52.972  1.00 129.05 ? 343 LYS B CB  1 
ATOM   6489  C CG  . LYS B 1 283 ? -11.903  -36.533 51.447  1.00 132.24 ? 343 LYS B CG  1 
ATOM   6490  C CD  . LYS B 1 283 ? -12.009  -37.933 50.882  1.00 124.44 ? 343 LYS B CD  1 
ATOM   6491  C CE  . LYS B 1 283 ? -12.186  -37.946 49.378  1.00 115.55 ? 343 LYS B CE  1 
ATOM   6492  N NZ  . LYS B 1 283 ? -11.948  -39.298 48.836  1.00 122.89 ? 343 LYS B NZ  1 
ATOM   6493  N N   . SER B 1 284 ? -14.708  -35.082 52.655  1.00 97.26  ? 344 SER B N   1 
ATOM   6494  C CA  . SER B 1 284 ? -15.830  -34.796 51.724  1.00 85.87  ? 344 SER B CA  1 
ATOM   6495  C C   . SER B 1 284 ? -16.513  -33.462 52.071  1.00 85.61  ? 344 SER B C   1 
ATOM   6496  O O   . SER B 1 284 ? -16.986  -32.790 51.128  1.00 86.99  ? 344 SER B O   1 
ATOM   6497  C CB  . SER B 1 284 ? -16.796  -35.959 51.693  1.00 89.60  ? 344 SER B CB  1 
ATOM   6498  O OG  . SER B 1 284 ? -16.874  -36.607 52.963  1.00 94.98  ? 344 SER B OG  1 
ATOM   6499  N N   . HIS B 1 285 ? -16.551  -33.065 53.356  1.00 78.77  ? 345 HIS B N   1 
ATOM   6500  C CA  . HIS B 1 285 ? -17.411  -31.961 53.863  1.00 72.71  ? 345 HIS B CA  1 
ATOM   6501  C C   . HIS B 1 285 ? -16.621  -30.953 54.709  1.00 61.29  ? 345 HIS B C   1 
ATOM   6502  O O   . HIS B 1 285 ? -15.493  -31.223 55.122  1.00 70.86  ? 345 HIS B O   1 
ATOM   6503  C CB  . HIS B 1 285 ? -18.599  -32.532 54.653  1.00 72.52  ? 345 HIS B CB  1 
ATOM   6504  C CG  . HIS B 1 285 ? -19.521  -33.430 53.880  1.00 71.14  ? 345 HIS B CG  1 
ATOM   6505  N ND1 . HIS B 1 285 ? -19.180  -34.729 53.545  1.00 63.73  ? 345 HIS B ND1 1 
ATOM   6506  C CD2 . HIS B 1 285 ? -20.774  -33.246 53.418  1.00 70.36  ? 345 HIS B CD2 1 
ATOM   6507  C CE1 . HIS B 1 285 ? -20.165  -35.288 52.873  1.00 64.08  ? 345 HIS B CE1 1 
ATOM   6508  N NE2 . HIS B 1 285 ? -21.149  -34.406 52.787  1.00 71.06  ? 345 HIS B NE2 1 
ATOM   6509  N N   . LEU B 1 286 ? -17.226  -29.800 54.941  1.00 53.33  ? 346 LEU B N   1 
ATOM   6510  C CA  . LEU B 1 286 ? -16.755  -28.798 55.923  1.00 54.97  ? 346 LEU B CA  1 
ATOM   6511  C C   . LEU B 1 286 ? -17.533  -29.044 57.231  1.00 63.35  ? 346 LEU B C   1 
ATOM   6512  O O   . LEU B 1 286 ? -18.594  -28.424 57.442  1.00 47.45  ? 346 LEU B O   1 
ATOM   6513  C CB  . LEU B 1 286 ? -16.999  -27.409 55.321  1.00 52.52  ? 346 LEU B CB  1 
ATOM   6514  C CG  . LEU B 1 286 ? -16.773  -26.201 56.228  1.00 50.74  ? 346 LEU B CG  1 
ATOM   6515  C CD1 . LEU B 1 286 ? -15.306  -26.029 56.570  1.00 54.20  ? 346 LEU B CD1 1 
ATOM   6516  C CD2 . LEU B 1 286 ? -17.286  -24.940 55.570  1.00 53.37  ? 346 LEU B CD2 1 
ATOM   6517  N N   . VAL B 1 287 ? -17.055  -29.994 58.043  1.00 64.51  ? 347 VAL B N   1 
ATOM   6518  C CA  . VAL B 1 287 ? -17.737  -30.479 59.280  1.00 55.57  ? 347 VAL B CA  1 
ATOM   6519  C C   . VAL B 1 287 ? -17.012  -29.900 60.499  1.00 60.79  ? 347 VAL B C   1 
ATOM   6520  O O   . VAL B 1 287 ? -15.778  -29.738 60.443  1.00 63.94  ? 347 VAL B O   1 
ATOM   6521  C CB  . VAL B 1 287 ? -17.818  -32.021 59.346  1.00 52.99  ? 347 VAL B CB  1 
ATOM   6522  C CG1 . VAL B 1 287 ? -18.542  -32.581 58.156  1.00 53.06  ? 347 VAL B CG1 1 
ATOM   6523  C CG2 . VAL B 1 287 ? -16.474  -32.695 59.485  1.00 50.22  ? 347 VAL B CG2 1 
ATOM   6524  N N   . PHE B 1 288 ? -17.754  -29.621 61.575  1.00 63.91  ? 348 PHE B N   1 
ATOM   6525  C CA  . PHE B 1 288 ? -17.273  -28.945 62.811  1.00 59.84  ? 348 PHE B CA  1 
ATOM   6526  C C   . PHE B 1 288 ? -18.130  -29.471 63.956  1.00 52.40  ? 348 PHE B C   1 
ATOM   6527  O O   . PHE B 1 288 ? -19.283  -29.637 63.667  1.00 66.23  ? 348 PHE B O   1 
ATOM   6528  C CB  . PHE B 1 288 ? -17.417  -27.427 62.661  1.00 55.53  ? 348 PHE B CB  1 
ATOM   6529  C CG  . PHE B 1 288 ? -17.220  -26.666 63.940  1.00 53.99  ? 348 PHE B CG  1 
ATOM   6530  C CD1 . PHE B 1 288 ? -15.952  -26.452 64.443  1.00 56.86  ? 348 PHE B CD1 1 
ATOM   6531  C CD2 . PHE B 1 288 ? -18.295  -26.166 64.638  1.00 56.38  ? 348 PHE B CD2 1 
ATOM   6532  C CE1 . PHE B 1 288 ? -15.762  -25.726 65.607  1.00 57.62  ? 348 PHE B CE1 1 
ATOM   6533  C CE2 . PHE B 1 288 ? -18.106  -25.450 65.810  1.00 57.10  ? 348 PHE B CE2 1 
ATOM   6534  C CZ  . PHE B 1 288 ? -16.839  -25.226 66.289  1.00 55.09  ? 348 PHE B CZ  1 
ATOM   6535  N N   . ASN B 1 289 ? -17.599  -29.744 65.143  1.00 51.84  ? 349 ASN B N   1 
ATOM   6536  C CA  . ASN B 1 289 ? -18.376  -30.344 66.272  1.00 59.77  ? 349 ASN B CA  1 
ATOM   6537  C C   . ASN B 1 289 ? -18.287  -29.399 67.477  1.00 57.45  ? 349 ASN B C   1 
ATOM   6538  O O   . ASN B 1 289 ? -17.203  -29.227 68.002  1.00 73.41  ? 349 ASN B O   1 
ATOM   6539  C CB  . ASN B 1 289 ? -17.927  -31.781 66.599  1.00 57.93  ? 349 ASN B CB  1 
ATOM   6540  C CG  . ASN B 1 289 ? -18.785  -32.471 67.650  1.00 58.42  ? 349 ASN B CG  1 
ATOM   6541  O OD1 . ASN B 1 289 ? -18.888  -31.970 68.768  1.00 62.25  ? 349 ASN B OD1 1 
ATOM   6542  N ND2 . ASN B 1 289 ? -19.371  -33.628 67.325  1.00 57.52  ? 349 ASN B ND2 1 
ATOM   6543  N N   . ASP B 1 290 ? -19.392  -28.811 67.909  1.00 58.75  ? 350 ASP B N   1 
ATOM   6544  C CA  . ASP B 1 290 ? -19.369  -27.733 68.932  1.00 69.10  ? 350 ASP B CA  1 
ATOM   6545  C C   . ASP B 1 290 ? -18.851  -28.300 70.267  1.00 65.71  ? 350 ASP B C   1 
ATOM   6546  O O   . ASP B 1 290 ? -18.109  -27.582 70.973  1.00 59.42  ? 350 ASP B O   1 
ATOM   6547  C CB  . ASP B 1 290 ? -20.742  -27.060 69.045  1.00 77.59  ? 350 ASP B CB  1 
ATOM   6548  C CG  . ASP B 1 290 ? -20.680  -25.567 69.313  1.00 71.63  ? 350 ASP B CG  1 
ATOM   6549  O OD1 . ASP B 1 290 ? -19.583  -24.990 69.203  1.00 76.31  ? 350 ASP B OD1 1 
ATOM   6550  O OD2 . ASP B 1 290 ? -21.736  -24.997 69.635  1.00 67.83  ? 350 ASP B OD2 1 
ATOM   6551  N N   . ASP B 1 291 ? -19.181  -29.556 70.567  1.00 67.04  ? 351 ASP B N   1 
ATOM   6552  C CA  . ASP B 1 291 ? -18.831  -30.230 71.847  1.00 75.99  ? 351 ASP B CA  1 
ATOM   6553  C C   . ASP B 1 291 ? -17.327  -30.522 71.894  1.00 73.03  ? 351 ASP B C   1 
ATOM   6554  O O   . ASP B 1 291 ? -16.703  -30.248 72.952  1.00 61.74  ? 351 ASP B O   1 
ATOM   6555  C CB  . ASP B 1 291 ? -19.639  -31.518 72.048  1.00 84.08  ? 351 ASP B CB  1 
ATOM   6556  C CG  . ASP B 1 291 ? -21.108  -31.406 71.667  1.00 93.24  ? 351 ASP B CG  1 
ATOM   6557  O OD1 . ASP B 1 291 ? -21.718  -30.336 71.938  1.00 89.52  ? 351 ASP B OD1 1 
ATOM   6558  O OD2 . ASP B 1 291 ? -21.626  -32.400 71.074  1.00 119.41 ? 351 ASP B OD2 1 
ATOM   6559  N N   . ILE B 1 292 ? -16.762  -31.065 70.807  1.00 69.00  ? 352 ILE B N   1 
ATOM   6560  C CA  . ILE B 1 292 ? -15.325  -31.468 70.760  1.00 72.01  ? 352 ILE B CA  1 
ATOM   6561  C C   . ILE B 1 292 ? -14.487  -30.215 70.482  1.00 62.46  ? 352 ILE B C   1 
ATOM   6562  O O   . ILE B 1 292 ? -13.724  -29.789 71.378  1.00 71.39  ? 352 ILE B O   1 
ATOM   6563  C CB  . ILE B 1 292 ? -15.070  -32.596 69.735  1.00 74.00  ? 352 ILE B CB  1 
ATOM   6564  C CG1 . ILE B 1 292 ? -15.932  -33.834 70.014  1.00 69.47  ? 352 ILE B CG1 1 
ATOM   6565  C CG2 . ILE B 1 292 ? -13.582  -32.950 69.670  1.00 74.01  ? 352 ILE B CG2 1 
ATOM   6566  C CD1 . ILE B 1 292 ? -16.026  -34.788 68.817  1.00 71.95  ? 352 ILE B CD1 1 
ATOM   6567  N N   . GLN B 1 293 ? -14.663  -29.634 69.304  1.00 53.96  ? 353 GLN B N   1 
ATOM   6568  C CA  . GLN B 1 293 ? -13.811  -28.554 68.747  1.00 61.09  ? 353 GLN B CA  1 
ATOM   6569  C C   . GLN B 1 293 ? -14.199  -27.188 69.344  1.00 65.82  ? 353 GLN B C   1 
ATOM   6570  O O   . GLN B 1 293 ? -13.278  -26.415 69.675  1.00 72.12  ? 353 GLN B O   1 
ATOM   6571  C CB  . GLN B 1 293 ? -13.894  -28.571 67.211  1.00 61.11  ? 353 GLN B CB  1 
ATOM   6572  C CG  . GLN B 1 293 ? -13.312  -29.841 66.588  1.00 58.18  ? 353 GLN B CG  1 
ATOM   6573  C CD  . GLN B 1 293 ? -13.709  -30.087 65.149  1.00 60.60  ? 353 GLN B CD  1 
ATOM   6574  O OE1 . GLN B 1 293 ? -14.797  -29.749 64.694  1.00 64.38  ? 353 GLN B OE1 1 
ATOM   6575  N NE2 . GLN B 1 293 ? -12.853  -30.765 64.417  1.00 62.52  ? 353 GLN B NE2 1 
ATOM   6576  N N   . GLY B 1 294 ? -15.496  -26.869 69.454  1.00 64.45  ? 354 GLY B N   1 
ATOM   6577  C CA  . GLY B 1 294 ? -15.944  -25.518 69.838  1.00 65.84  ? 354 GLY B CA  1 
ATOM   6578  C C   . GLY B 1 294 ? -15.596  -25.210 71.284  1.00 67.06  ? 354 GLY B C   1 
ATOM   6579  O O   . GLY B 1 294 ? -15.103  -24.087 71.573  1.00 59.52  ? 354 GLY B O   1 
ATOM   6580  N N   . THR B 1 295 ? -15.843  -26.187 72.159  1.00 64.00  ? 355 THR B N   1 
ATOM   6581  C CA  . THR B 1 295 ? -15.606  -26.102 73.622  1.00 64.70  ? 355 THR B CA  1 
ATOM   6582  C C   . THR B 1 295 ? -14.088  -26.067 73.850  1.00 66.42  ? 355 THR B C   1 
ATOM   6583  O O   . THR B 1 295 ? -13.607  -25.125 74.533  1.00 61.76  ? 355 THR B O   1 
ATOM   6584  C CB  . THR B 1 295 ? -16.312  -27.265 74.330  1.00 64.72  ? 355 THR B CB  1 
ATOM   6585  O OG1 . THR B 1 295 ? -17.688  -27.283 73.944  1.00 60.54  ? 355 THR B OG1 1 
ATOM   6586  C CG2 . THR B 1 295 ? -16.230  -27.200 75.836  1.00 68.50  ? 355 THR B CG2 1 
ATOM   6587  N N   . ALA B 1 296 ? -13.358  -27.035 73.273  1.00 61.95  ? 356 ALA B N   1 
ATOM   6588  C CA  . ALA B 1 296 ? -11.880  -27.068 73.278  1.00 56.01  ? 356 ALA B CA  1 
ATOM   6589  C C   . ALA B 1 296 ? -11.361  -25.653 73.000  1.00 51.17  ? 356 ALA B C   1 
ATOM   6590  O O   . ALA B 1 296 ? -10.508  -25.179 73.730  1.00 56.34  ? 356 ALA B O   1 
ATOM   6591  C CB  . ALA B 1 296 ? -11.367  -28.054 72.266  1.00 48.74  ? 356 ALA B CB  1 
ATOM   6592  N N   . SER B 1 297 ? -11.909  -24.998 71.990  1.00 49.00  ? 357 SER B N   1 
ATOM   6593  C CA  . SER B 1 297 ? -11.446  -23.686 71.503  1.00 50.08  ? 357 SER B CA  1 
ATOM   6594  C C   . SER B 1 297 ? -11.599  -22.641 72.600  1.00 51.83  ? 357 SER B C   1 
ATOM   6595  O O   . SER B 1 297 ? -10.614  -21.954 72.865  1.00 49.24  ? 357 SER B O   1 
ATOM   6596  C CB  . SER B 1 297 ? -12.199  -23.284 70.270  1.00 53.11  ? 357 SER B CB  1 
ATOM   6597  O OG  . SER B 1 297 ? -11.538  -22.191 69.646  1.00 57.14  ? 357 SER B OG  1 
ATOM   6598  N N   . VAL B 1 298 ? -12.780  -22.539 73.217  1.00 53.92  ? 358 VAL B N   1 
ATOM   6599  C CA  . VAL B 1 298 ? -13.104  -21.442 74.181  1.00 52.54  ? 358 VAL B CA  1 
ATOM   6600  C C   . VAL B 1 298 ? -12.374  -21.672 75.508  1.00 56.23  ? 358 VAL B C   1 
ATOM   6601  O O   . VAL B 1 298 ? -12.046  -20.667 76.217  1.00 45.34  ? 358 VAL B O   1 
ATOM   6602  C CB  . VAL B 1 298 ? -14.617  -21.318 74.422  1.00 49.65  ? 358 VAL B CB  1 
ATOM   6603  C CG1 . VAL B 1 298 ? -15.191  -22.559 75.092  1.00 51.95  ? 358 VAL B CG1 1 
ATOM   6604  C CG2 . VAL B 1 298 ? -14.951  -20.056 75.204  1.00 46.02  ? 358 VAL B CG2 1 
ATOM   6605  N N   . VAL B 1 299 ? -12.169  -22.944 75.855  1.00 50.91  ? 359 VAL B N   1 
ATOM   6606  C CA  . VAL B 1 299 ? -11.440  -23.341 77.085  1.00 47.12  ? 359 VAL B CA  1 
ATOM   6607  C C   . VAL B 1 299 ? -9.994   -22.886 76.930  1.00 50.05  ? 359 VAL B C   1 
ATOM   6608  O O   . VAL B 1 299 ? -9.492   -22.205 77.837  1.00 59.70  ? 359 VAL B O   1 
ATOM   6609  C CB  . VAL B 1 299 ? -11.540  -24.853 77.335  1.00 48.19  ? 359 VAL B CB  1 
ATOM   6610  C CG1 . VAL B 1 299 ? -10.539  -25.307 78.386  1.00 48.54  ? 359 VAL B CG1 1 
ATOM   6611  C CG2 . VAL B 1 299 ? -12.954  -25.256 77.731  1.00 48.98  ? 359 VAL B CG2 1 
ATOM   6612  N N   . LEU B 1 300 ? -9.348   -23.255 75.826  1.00 53.69  ? 360 LEU B N   1 
ATOM   6613  C CA  . LEU B 1 300 ? -7.942   -22.864 75.555  1.00 58.21  ? 360 LEU B CA  1 
ATOM   6614  C C   . LEU B 1 300 ? -7.837   -21.339 75.638  1.00 51.17  ? 360 LEU B C   1 
ATOM   6615  O O   . LEU B 1 300 ? -6.886   -20.868 76.248  1.00 54.11  ? 360 LEU B O   1 
ATOM   6616  C CB  . LEU B 1 300 ? -7.499   -23.391 74.191  1.00 71.96  ? 360 LEU B CB  1 
ATOM   6617  C CG  . LEU B 1 300 ? -5.989   -23.350 73.936  1.00 73.82  ? 360 LEU B CG  1 
ATOM   6618  C CD1 . LEU B 1 300 ? -5.643   -24.227 72.745  1.00 75.83  ? 360 LEU B CD1 1 
ATOM   6619  C CD2 . LEU B 1 300 ? -5.497   -21.927 73.684  1.00 77.54  ? 360 LEU B CD2 1 
ATOM   6620  N N   . ALA B 1 301 ? -8.812   -20.603 75.113  1.00 49.02  ? 361 ALA B N   1 
ATOM   6621  C CA  . ALA B 1 301 ? -8.852   -19.120 75.159  1.00 53.54  ? 361 ALA B CA  1 
ATOM   6622  C C   . ALA B 1 301 ? -8.972   -18.651 76.602  1.00 50.84  ? 361 ALA B C   1 
ATOM   6623  O O   . ALA B 1 301 ? -8.339   -17.651 76.957  1.00 53.08  ? 361 ALA B O   1 
ATOM   6624  C CB  . ALA B 1 301 ? -10.006  -18.585 74.343  1.00 63.02  ? 361 ALA B CB  1 
ATOM   6625  N N   . GLY B 1 302 ? -9.788   -19.339 77.388  1.00 46.77  ? 362 GLY B N   1 
ATOM   6626  C CA  . GLY B 1 302 ? -9.922   -19.048 78.826  1.00 56.08  ? 362 GLY B CA  1 
ATOM   6627  C C   . GLY B 1 302 ? -8.616   -19.232 79.551  1.00 56.18  ? 362 GLY B C   1 
ATOM   6628  O O   . GLY B 1 302 ? -8.241   -18.315 80.295  1.00 61.49  ? 362 GLY B O   1 
ATOM   6629  N N   . LEU B 1 303 ? -7.946   -20.371 79.336  1.00 55.47  ? 363 LEU B N   1 
ATOM   6630  C CA  . LEU B 1 303 ? -6.615   -20.665 79.916  1.00 53.35  ? 363 LEU B CA  1 
ATOM   6631  C C   . LEU B 1 303 ? -5.655   -19.531 79.566  1.00 53.71  ? 363 LEU B C   1 
ATOM   6632  O O   . LEU B 1 303 ? -5.104   -18.974 80.500  1.00 57.28  ? 363 LEU B O   1 
ATOM   6633  C CB  . LEU B 1 303 ? -6.135   -22.021 79.410  1.00 53.81  ? 363 LEU B CB  1 
ATOM   6634  C CG  . LEU B 1 303 ? -6.961   -23.186 79.943  1.00 53.55  ? 363 LEU B CG  1 
ATOM   6635  C CD1 . LEU B 1 303 ? -6.559   -24.508 79.301  1.00 56.09  ? 363 LEU B CD1 1 
ATOM   6636  C CD2 . LEU B 1 303 ? -6.846   -23.255 81.450  1.00 52.10  ? 363 LEU B CD2 1 
ATOM   6637  N N   . LEU B 1 304 ? -5.510   -19.157 78.293  1.00 56.79  ? 364 LEU B N   1 
ATOM   6638  C CA  . LEU B 1 304 ? -4.564   -18.084 77.852  1.00 59.65  ? 364 LEU B CA  1 
ATOM   6639  C C   . LEU B 1 304 ? -4.924   -16.764 78.550  1.00 58.76  ? 364 LEU B C   1 
ATOM   6640  O O   . LEU B 1 304 ? -4.002   -15.993 78.901  1.00 62.86  ? 364 LEU B O   1 
ATOM   6641  C CB  . LEU B 1 304 ? -4.598   -17.887 76.330  1.00 59.16  ? 364 LEU B CB  1 
ATOM   6642  C CG  . LEU B 1 304 ? -4.140   -19.049 75.444  1.00 56.75  ? 364 LEU B CG  1 
ATOM   6643  C CD1 . LEU B 1 304 ? -4.403   -18.727 73.989  1.00 54.39  ? 364 LEU B CD1 1 
ATOM   6644  C CD2 . LEU B 1 304 ? -2.677   -19.413 75.670  1.00 61.55  ? 364 LEU B CD2 1 
ATOM   6645  N N   . ALA B 1 305 ? -6.217   -16.511 78.751  1.00 62.37  ? 365 ALA B N   1 
ATOM   6646  C CA  . ALA B 1 305 ? -6.747   -15.272 79.371  1.00 66.52  ? 365 ALA B CA  1 
ATOM   6647  C C   . ALA B 1 305 ? -6.464   -15.309 80.873  1.00 65.16  ? 365 ALA B C   1 
ATOM   6648  O O   . ALA B 1 305 ? -6.179   -14.215 81.451  1.00 54.06  ? 365 ALA B O   1 
ATOM   6649  C CB  . ALA B 1 305 ? -8.218   -15.123 79.084  1.00 65.59  ? 365 ALA B CB  1 
ATOM   6650  N N   . ALA B 1 306 ? -6.535   -16.512 81.465  1.00 60.76  ? 366 ALA B N   1 
ATOM   6651  C CA  . ALA B 1 306 ? -6.276   -16.778 82.904  1.00 60.03  ? 366 ALA B CA  1 
ATOM   6652  C C   . ALA B 1 306 ? -4.818   -16.462 83.195  1.00 57.85  ? 366 ALA B C   1 
ATOM   6653  O O   . ALA B 1 306 ? -4.559   -15.792 84.192  1.00 61.65  ? 366 ALA B O   1 
ATOM   6654  C CB  . ALA B 1 306 ? -6.600   -18.216 83.282  1.00 62.13  ? 366 ALA B CB  1 
ATOM   6655  N N   . LEU B 1 307 ? -3.925   -16.911 82.307  1.00 61.98  ? 367 LEU B N   1 
ATOM   6656  C CA  . LEU B 1 307 ? -2.461   -16.848 82.503  1.00 59.56  ? 367 LEU B CA  1 
ATOM   6657  C C   . LEU B 1 307 ? -1.976   -15.418 82.329  1.00 55.76  ? 367 LEU B C   1 
ATOM   6658  O O   . LEU B 1 307 ? -0.857   -15.156 82.772  1.00 70.56  ? 367 LEU B O   1 
ATOM   6659  C CB  . LEU B 1 307 ? -1.763   -17.806 81.542  1.00 61.54  ? 367 LEU B CB  1 
ATOM   6660  C CG  . LEU B 1 307 ? -2.055   -19.285 81.775  1.00 61.57  ? 367 LEU B CG  1 
ATOM   6661  C CD1 . LEU B 1 307 ? -1.256   -20.105 80.789  1.00 70.03  ? 367 LEU B CD1 1 
ATOM   6662  C CD2 . LEU B 1 307 ? -1.756   -19.700 83.206  1.00 54.38  ? 367 LEU B CD2 1 
ATOM   6663  N N   . LYS B 1 308 ? -2.811   -14.530 81.795  1.00 59.85  ? 368 LYS B N   1 
ATOM   6664  C CA  . LYS B 1 308 ? -2.539   -13.074 81.820  1.00 62.28  ? 368 LYS B CA  1 
ATOM   6665  C C   . LYS B 1 308 ? -2.905   -12.491 83.186  1.00 67.53  ? 368 LYS B C   1 
ATOM   6666  O O   . LYS B 1 308 ? -2.244   -11.539 83.587  1.00 80.61  ? 368 LYS B O   1 
ATOM   6667  C CB  . LYS B 1 308 ? -3.295   -12.400 80.684  1.00 66.08  ? 368 LYS B CB  1 
ATOM   6668  C CG  . LYS B 1 308 ? -2.929   -12.963 79.317  1.00 69.39  ? 368 LYS B CG  1 
ATOM   6669  C CD  . LYS B 1 308 ? -3.887   -12.599 78.203  1.00 70.01  ? 368 LYS B CD  1 
ATOM   6670  C CE  . LYS B 1 308 ? -3.630   -11.244 77.588  1.00 71.45  ? 368 LYS B CE  1 
ATOM   6671  N NZ  . LYS B 1 308 ? -4.593   -10.997 76.492  1.00 72.39  ? 368 LYS B NZ  1 
ATOM   6672  N N   . MET B 1 309 ? -3.915   -13.017 83.878  1.00 64.08  ? 369 MET B N   1 
ATOM   6673  C CA  . MET B 1 309 ? -4.280   -12.491 85.218  1.00 71.43  ? 369 MET B CA  1 
ATOM   6674  C C   . MET B 1 309 ? -3.262   -12.984 86.261  1.00 63.90  ? 369 MET B C   1 
ATOM   6675  O O   . MET B 1 309 ? -2.866   -12.198 87.105  1.00 52.10  ? 369 MET B O   1 
ATOM   6676  C CB  . MET B 1 309 ? -5.676   -12.936 85.674  1.00 85.08  ? 369 MET B CB  1 
ATOM   6677  C CG  . MET B 1 309 ? -6.801   -12.790 84.685  1.00 89.67  ? 369 MET B CG  1 
ATOM   6678  S SD  . MET B 1 309 ? -8.218   -13.723 85.343  1.00 92.83  ? 369 MET B SD  1 
ATOM   6679  C CE  . MET B 1 309 ? -9.271   -12.408 85.943  1.00 91.58  ? 369 MET B CE  1 
ATOM   6680  N N   . VAL B 1 310 ? -2.905   -14.266 86.217  1.00 72.11  ? 370 VAL B N   1 
ATOM   6681  C CA  . VAL B 1 310 ? -2.153   -15.015 87.276  1.00 79.50  ? 370 VAL B CA  1 
ATOM   6682  C C   . VAL B 1 310 ? -0.672   -15.170 86.882  1.00 80.45  ? 370 VAL B C   1 
ATOM   6683  O O   . VAL B 1 310 ? 0.159    -15.327 87.818  1.00 74.16  ? 370 VAL B O   1 
ATOM   6684  C CB  . VAL B 1 310 ? -2.794   -16.399 87.530  1.00 89.20  ? 370 VAL B CB  1 
ATOM   6685  C CG1 . VAL B 1 310 ? -1.898   -17.333 88.347  1.00 97.11  ? 370 VAL B CG1 1 
ATOM   6686  C CG2 . VAL B 1 310 ? -4.178   -16.266 88.154  1.00 89.51  ? 370 VAL B CG2 1 
ATOM   6687  N N   . GLY B 1 311 ? -0.347   -15.163 85.578  1.00 73.75  ? 371 GLY B N   1 
ATOM   6688  C CA  . GLY B 1 311 ? 1.023    -15.331 85.060  1.00 66.61  ? 371 GLY B CA  1 
ATOM   6689  C C   . GLY B 1 311 ? 1.337    -16.775 84.698  1.00 73.82  ? 371 GLY B C   1 
ATOM   6690  O O   . GLY B 1 311 ? 0.757    -17.696 85.317  1.00 74.91  ? 371 GLY B O   1 
ATOM   6691  N N   . GLY B 1 312 ? 2.251    -16.962 83.731  1.00 79.05  ? 372 GLY B N   1 
ATOM   6692  C CA  . GLY B 1 312 ? 2.857    -18.252 83.346  1.00 71.11  ? 372 GLY B CA  1 
ATOM   6693  C C   . GLY B 1 312 ? 2.449    -18.682 81.949  1.00 70.15  ? 372 GLY B C   1 
ATOM   6694  O O   . GLY B 1 312 ? 1.828    -17.891 81.225  1.00 65.02  ? 372 GLY B O   1 
ATOM   6695  N N   . THR B 1 313 ? 2.775    -19.921 81.604  1.00 68.63  ? 373 THR B N   1 
ATOM   6696  C CA  . THR B 1 313 ? 2.588    -20.518 80.261  1.00 66.05  ? 373 THR B CA  1 
ATOM   6697  C C   . THR B 1 313 ? 1.728    -21.763 80.401  1.00 55.97  ? 373 THR B C   1 
ATOM   6698  O O   . THR B 1 313 ? 1.572    -22.199 81.520  1.00 49.31  ? 373 THR B O   1 
ATOM   6699  C CB  . THR B 1 313 ? 3.938    -20.882 79.639  1.00 74.07  ? 373 THR B CB  1 
ATOM   6700  O OG1 . THR B 1 313 ? 4.415    -22.052 80.324  1.00 74.14  ? 373 THR B OG1 1 
ATOM   6701  C CG2 . THR B 1 313 ? 4.922    -19.730 79.699  1.00 74.92  ? 373 THR B CG2 1 
ATOM   6702  N N   . LEU B 1 314 ? 1.204    -22.290 79.298  1.00 55.18  ? 374 LEU B N   1 
ATOM   6703  C CA  . LEU B 1 314 ? 0.423    -23.556 79.304  1.00 67.57  ? 374 LEU B CA  1 
ATOM   6704  C C   . LEU B 1 314 ? 1.368    -24.685 79.733  1.00 68.79  ? 374 LEU B C   1 
ATOM   6705  O O   . LEU B 1 314 ? 0.960    -25.554 80.524  1.00 58.96  ? 374 LEU B O   1 
ATOM   6706  C CB  . LEU B 1 314 ? -0.184   -23.829 77.920  1.00 70.63  ? 374 LEU B CB  1 
ATOM   6707  C CG  . LEU B 1 314 ? -1.272   -22.855 77.451  1.00 76.50  ? 374 LEU B CG  1 
ATOM   6708  C CD1 . LEU B 1 314 ? -1.804   -23.255 76.089  1.00 76.12  ? 374 LEU B CD1 1 
ATOM   6709  C CD2 . LEU B 1 314 ? -2.425   -22.769 78.450  1.00 83.02  ? 374 LEU B CD2 1 
ATOM   6710  N N   . ALA B 1 315 ? 2.604    -24.644 79.237  1.00 76.01  ? 375 ALA B N   1 
ATOM   6711  C CA  . ALA B 1 315 ? 3.618    -25.700 79.444  1.00 81.99  ? 375 ALA B CA  1 
ATOM   6712  C C   . ALA B 1 315 ? 3.681    -26.047 80.934  1.00 77.83  ? 375 ALA B C   1 
ATOM   6713  O O   . ALA B 1 315 ? 3.458    -27.253 81.256  1.00 76.73  ? 375 ALA B O   1 
ATOM   6714  C CB  . ALA B 1 315 ? 4.955    -25.243 78.919  1.00 84.14  ? 375 ALA B CB  1 
ATOM   6715  N N   . GLU B 1 316 ? 3.906    -25.032 81.786  1.00 68.42  ? 376 GLU B N   1 
ATOM   6716  C CA  . GLU B 1 316 ? 4.247    -25.196 83.231  1.00 72.53  ? 376 GLU B CA  1 
ATOM   6717  C C   . GLU B 1 316 ? 3.072    -25.738 84.048  1.00 73.62  ? 376 GLU B C   1 
ATOM   6718  O O   . GLU B 1 316 ? 3.341    -26.364 85.080  1.00 73.82  ? 376 GLU B O   1 
ATOM   6719  C CB  . GLU B 1 316 ? 4.629    -23.881 83.896  1.00 77.11  ? 376 GLU B CB  1 
ATOM   6720  C CG  . GLU B 1 316 ? 5.798    -23.176 83.232  1.00 84.83  ? 376 GLU B CG  1 
ATOM   6721  C CD  . GLU B 1 316 ? 5.664    -21.660 83.192  1.00 96.08  ? 376 GLU B CD  1 
ATOM   6722  O OE1 . GLU B 1 316 ? 4.798    -21.099 83.921  1.00 85.90  ? 376 GLU B OE1 1 
ATOM   6723  O OE2 . GLU B 1 316 ? 6.453    -21.037 82.471  1.00 110.50 ? 376 GLU B OE2 1 
ATOM   6724  N N   . GLN B 1 317 ? 1.823    -25.512 83.629  1.00 72.82  ? 377 GLN B N   1 
ATOM   6725  C CA  . GLN B 1 317 ? 0.613    -25.865 84.428  1.00 63.34  ? 377 GLN B CA  1 
ATOM   6726  C C   . GLN B 1 317 ? 0.419    -27.390 84.426  1.00 66.59  ? 377 GLN B C   1 
ATOM   6727  O O   . GLN B 1 317 ? 0.898    -28.083 83.485  1.00 57.65  ? 377 GLN B O   1 
ATOM   6728  C CB  . GLN B 1 317 ? -0.633   -25.190 83.846  1.00 71.89  ? 377 GLN B CB  1 
ATOM   6729  C CG  . GLN B 1 317 ? -0.489   -23.698 83.569  1.00 64.17  ? 377 GLN B CG  1 
ATOM   6730  C CD  . GLN B 1 317 ? -0.051   -22.884 84.763  1.00 61.68  ? 377 GLN B CD  1 
ATOM   6731  O OE1 . GLN B 1 317 ? -0.556   -23.031 85.866  1.00 62.69  ? 377 GLN B OE1 1 
ATOM   6732  N NE2 . GLN B 1 317 ? 0.868    -21.963 84.533  1.00 63.53  ? 377 GLN B NE2 1 
ATOM   6733  N N   . THR B 1 318 ? -0.281   -27.918 85.433  1.00 78.80  ? 378 THR B N   1 
ATOM   6734  C CA  . THR B 1 318 ? -0.746   -29.345 85.485  1.00 87.45  ? 378 THR B CA  1 
ATOM   6735  C C   . THR B 1 318 ? -2.283   -29.393 85.492  1.00 95.50  ? 378 THR B C   1 
ATOM   6736  O O   . THR B 1 318 ? -2.885   -28.695 86.355  1.00 89.82  ? 378 THR B O   1 
ATOM   6737  C CB  . THR B 1 318 ? -0.162   -30.088 86.695  1.00 80.56  ? 378 THR B CB  1 
ATOM   6738  O OG1 . THR B 1 318 ? 1.242    -29.829 86.731  1.00 88.53  ? 378 THR B OG1 1 
ATOM   6739  C CG2 . THR B 1 318 ? -0.411   -31.579 86.665  1.00 74.72  ? 378 THR B CG2 1 
ATOM   6740  N N   . TYR B 1 319 ? -2.880   -30.172 84.575  1.00 85.03  ? 379 TYR B N   1 
ATOM   6741  C CA  . TYR B 1 319 ? -4.329   -30.208 84.238  1.00 71.86  ? 379 TYR B CA  1 
ATOM   6742  C C   . TYR B 1 319 ? -4.973   -31.489 84.781  1.00 76.04  ? 379 TYR B C   1 
ATOM   6743  O O   . TYR B 1 319 ? -4.491   -32.598 84.458  1.00 74.77  ? 379 TYR B O   1 
ATOM   6744  C CB  . TYR B 1 319 ? -4.513   -30.148 82.719  1.00 67.29  ? 379 TYR B CB  1 
ATOM   6745  C CG  . TYR B 1 319 ? -3.813   -28.982 82.071  1.00 61.06  ? 379 TYR B CG  1 
ATOM   6746  C CD1 . TYR B 1 319 ? -2.517   -29.081 81.596  1.00 57.87  ? 379 TYR B CD1 1 
ATOM   6747  C CD2 . TYR B 1 319 ? -4.449   -27.761 81.970  1.00 61.93  ? 379 TYR B CD2 1 
ATOM   6748  C CE1 . TYR B 1 319 ? -1.871   -27.981 81.060  1.00 66.75  ? 379 TYR B CE1 1 
ATOM   6749  C CE2 . TYR B 1 319 ? -3.821   -26.656 81.426  1.00 63.48  ? 379 TYR B CE2 1 
ATOM   6750  C CZ  . TYR B 1 319 ? -2.526   -26.764 80.970  1.00 62.39  ? 379 TYR B CZ  1 
ATOM   6751  O OH  . TYR B 1 319 ? -1.925   -25.667 80.431  1.00 52.61  ? 379 TYR B OH  1 
ATOM   6752  N N   . LEU B 1 320 ? -6.042   -31.330 85.567  1.00 77.70  ? 380 LEU B N   1 
ATOM   6753  C CA  . LEU B 1 320 ? -6.936   -32.437 85.974  1.00 76.86  ? 380 LEU B CA  1 
ATOM   6754  C C   . LEU B 1 320 ? -8.367   -32.177 85.466  1.00 80.00  ? 380 LEU B C   1 
ATOM   6755  O O   . LEU B 1 320 ? -8.952   -31.126 85.831  1.00 68.62  ? 380 LEU B O   1 
ATOM   6756  C CB  . LEU B 1 320 ? -6.915   -32.575 87.495  1.00 72.55  ? 380 LEU B CB  1 
ATOM   6757  C CG  . LEU B 1 320 ? -7.599   -33.848 88.007  1.00 84.39  ? 380 LEU B CG  1 
ATOM   6758  C CD1 . LEU B 1 320 ? -7.060   -35.090 87.278  1.00 77.71  ? 380 LEU B CD1 1 
ATOM   6759  C CD2 . LEU B 1 320 ? -7.458   -33.977 89.519  1.00 89.56  ? 380 LEU B CD2 1 
ATOM   6760  N N   . PHE B 1 321 ? -8.899   -33.142 84.705  1.00 79.30  ? 381 PHE B N   1 
ATOM   6761  C CA  . PHE B 1 321 ? -10.283  -33.206 84.171  1.00 72.04  ? 381 PHE B CA  1 
ATOM   6762  C C   . PHE B 1 321 ? -11.120  -34.227 84.958  1.00 69.48  ? 381 PHE B C   1 
ATOM   6763  O O   . PHE B 1 321 ? -10.690  -35.395 85.165  1.00 59.03  ? 381 PHE B O   1 
ATOM   6764  C CB  . PHE B 1 321 ? -10.281  -33.622 82.694  1.00 71.52  ? 381 PHE B CB  1 
ATOM   6765  C CG  . PHE B 1 321 ? -9.741   -32.586 81.745  1.00 75.39  ? 381 PHE B CG  1 
ATOM   6766  C CD1 . PHE B 1 321 ? -8.383   -32.497 81.493  1.00 85.35  ? 381 PHE B CD1 1 
ATOM   6767  C CD2 . PHE B 1 321 ? -10.576  -31.669 81.121  1.00 74.99  ? 381 PHE B CD2 1 
ATOM   6768  C CE1 . PHE B 1 321 ? -7.874   -31.527 80.633  1.00 80.20  ? 381 PHE B CE1 1 
ATOM   6769  C CE2 . PHE B 1 321 ? -10.064  -30.704 80.263  1.00 79.97  ? 381 PHE B CE2 1 
ATOM   6770  C CZ  . PHE B 1 321 ? -8.715   -30.640 80.014  1.00 78.13  ? 381 PHE B CZ  1 
ATOM   6771  N N   . LEU B 1 322 ? -12.326  -33.811 85.356  1.00 69.25  ? 382 LEU B N   1 
ATOM   6772  C CA  . LEU B 1 322 ? -13.424  -34.766 85.613  1.00 63.41  ? 382 LEU B CA  1 
ATOM   6773  C C   . LEU B 1 322 ? -14.236  -34.892 84.318  1.00 67.93  ? 382 LEU B C   1 
ATOM   6774  O O   . LEU B 1 322 ? -14.668  -33.831 83.798  1.00 58.14  ? 382 LEU B O   1 
ATOM   6775  C CB  . LEU B 1 322 ? -14.263  -34.263 86.786  1.00 66.20  ? 382 LEU B CB  1 
ATOM   6776  C CG  . LEU B 1 322 ? -15.360  -35.231 87.250  1.00 71.91  ? 382 LEU B CG  1 
ATOM   6777  C CD1 . LEU B 1 322 ? -14.788  -36.591 87.640  1.00 75.53  ? 382 LEU B CD1 1 
ATOM   6778  C CD2 . LEU B 1 322 ? -16.163  -34.650 88.398  1.00 69.73  ? 382 LEU B CD2 1 
ATOM   6779  N N   . GLY B 1 323 ? -14.360  -36.121 83.799  1.00 73.62  ? 383 GLY B N   1 
ATOM   6780  C CA  . GLY B 1 323 ? -15.143  -36.446 82.593  1.00 73.04  ? 383 GLY B CA  1 
ATOM   6781  C C   . GLY B 1 323 ? -14.279  -36.572 81.345  1.00 76.41  ? 383 GLY B C   1 
ATOM   6782  O O   . GLY B 1 323 ? -13.783  -35.528 80.851  1.00 85.52  ? 383 GLY B O   1 
ATOM   6783  N N   . ALA B 1 324 ? -14.135  -37.803 80.831  1.00 81.51  ? 384 ALA B N   1 
ATOM   6784  C CA  . ALA B 1 324 ? -13.277  -38.175 79.672  1.00 82.62  ? 384 ALA B CA  1 
ATOM   6785  C C   . ALA B 1 324 ? -14.137  -38.462 78.443  1.00 88.18  ? 384 ALA B C   1 
ATOM   6786  O O   . ALA B 1 324 ? -14.007  -39.570 77.882  1.00 86.64  ? 384 ALA B O   1 
ATOM   6787  C CB  . ALA B 1 324 ? -12.440  -39.391 80.004  1.00 77.68  ? 384 ALA B CB  1 
ATOM   6788  N N   . GLY B 1 325 ? -15.006  -37.530 78.070  1.00 93.48  ? 385 GLY B N   1 
ATOM   6789  C CA  . GLY B 1 325 ? -15.901  -37.704 76.915  1.00 92.00  ? 385 GLY B CA  1 
ATOM   6790  C C   . GLY B 1 325 ? -15.385  -36.963 75.702  1.00 88.41  ? 385 GLY B C   1 
ATOM   6791  O O   . GLY B 1 325 ? -14.144  -36.858 75.561  1.00 72.28  ? 385 GLY B O   1 
ATOM   6792  N N   . GLU B 1 326 ? -16.319  -36.438 74.905  1.00 92.71  ? 386 GLU B N   1 
ATOM   6793  C CA  . GLU B 1 326 ? -16.058  -35.520 73.762  1.00 104.70 ? 386 GLU B CA  1 
ATOM   6794  C C   . GLU B 1 326 ? -15.257  -34.324 74.293  1.00 99.48  ? 386 GLU B C   1 
ATOM   6795  O O   . GLU B 1 326 ? -14.072  -34.211 73.974  1.00 124.16 ? 386 GLU B O   1 
ATOM   6796  C CB  . GLU B 1 326 ? -17.351  -35.014 73.104  1.00 113.10 ? 386 GLU B CB  1 
ATOM   6797  C CG  . GLU B 1 326 ? -18.481  -36.028 72.993  1.00 111.46 ? 386 GLU B CG  1 
ATOM   6798  C CD  . GLU B 1 326 ? -19.508  -35.702 71.925  1.00 121.51 ? 386 GLU B CD  1 
ATOM   6799  O OE1 . GLU B 1 326 ? -20.488  -34.990 72.260  1.00 122.95 ? 386 GLU B OE1 1 
ATOM   6800  O OE2 . GLU B 1 326 ? -19.253  -36.030 70.751  1.00 122.65 ? 386 GLU B OE2 1 
ATOM   6801  N N   . ALA B 1 327 ? -15.878  -33.466 75.094  1.00 99.10  ? 387 ALA B N   1 
ATOM   6802  C CA  . ALA B 1 327 ? -15.273  -32.201 75.561  1.00 98.87  ? 387 ALA B CA  1 
ATOM   6803  C C   . ALA B 1 327 ? -14.015  -32.532 76.371  1.00 89.26  ? 387 ALA B C   1 
ATOM   6804  O O   . ALA B 1 327 ? -13.012  -31.827 76.185  1.00 90.63  ? 387 ALA B O   1 
ATOM   6805  C CB  . ALA B 1 327 ? -16.271  -31.389 76.357  1.00 97.72  ? 387 ALA B CB  1 
ATOM   6806  N N   . GLY B 1 328 ? -14.060  -33.565 77.222  1.00 80.16  ? 388 GLY B N   1 
ATOM   6807  C CA  . GLY B 1 328 ? -12.885  -34.011 77.991  1.00 87.39  ? 388 GLY B CA  1 
ATOM   6808  C C   . GLY B 1 328 ? -11.646  -34.129 77.111  1.00 85.54  ? 388 GLY B C   1 
ATOM   6809  O O   . GLY B 1 328 ? -10.800  -33.184 77.128  1.00 79.80  ? 388 GLY B O   1 
ATOM   6810  N N   . THR B 1 329 ? -11.560  -35.221 76.343  1.00 75.97  ? 389 THR B N   1 
ATOM   6811  C CA  . THR B 1 329 ? -10.393  -35.548 75.479  1.00 77.36  ? 389 THR B CA  1 
ATOM   6812  C C   . THR B 1 329 ? -10.186  -34.425 74.460  1.00 72.71  ? 389 THR B C   1 
ATOM   6813  O O   . THR B 1 329 ? -9.042   -34.062 74.223  1.00 81.47  ? 389 THR B O   1 
ATOM   6814  C CB  . THR B 1 329 ? -10.534  -36.930 74.828  1.00 80.97  ? 389 THR B CB  1 
ATOM   6815  O OG1 . THR B 1 329 ? -11.646  -36.920 73.928  1.00 86.16  ? 389 THR B OG1 1 
ATOM   6816  C CG2 . THR B 1 329 ? -10.705  -38.026 75.859  1.00 79.54  ? 389 THR B CG2 1 
ATOM   6817  N N   . GLY B 1 330 ? -11.268  -33.886 73.904  1.00 79.65  ? 390 GLY B N   1 
ATOM   6818  C CA  . GLY B 1 330 ? -11.256  -32.784 72.917  1.00 80.44  ? 390 GLY B CA  1 
ATOM   6819  C C   . GLY B 1 330 ? -10.530  -31.554 73.430  1.00 74.36  ? 390 GLY B C   1 
ATOM   6820  O O   . GLY B 1 330 ? -9.616   -31.081 72.745  1.00 68.62  ? 390 GLY B O   1 
ATOM   6821  N N   . ILE B 1 331 ? -10.905  -31.053 74.604  1.00 78.30  ? 391 ILE B N   1 
ATOM   6822  C CA  . ILE B 1 331 ? -10.235  -29.869 75.222  1.00 76.99  ? 391 ILE B CA  1 
ATOM   6823  C C   . ILE B 1 331 ? -8.764   -30.240 75.442  1.00 77.54  ? 391 ILE B C   1 
ATOM   6824  O O   . ILE B 1 331 ? -7.887   -29.452 75.052  1.00 84.33  ? 391 ILE B O   1 
ATOM   6825  C CB  . ILE B 1 331 ? -10.924  -29.418 76.527  1.00 71.13  ? 391 ILE B CB  1 
ATOM   6826  C CG1 . ILE B 1 331 ? -12.438  -29.248 76.375  1.00 77.62  ? 391 ILE B CG1 1 
ATOM   6827  C CG2 . ILE B 1 331 ? -10.313  -28.120 77.010  1.00 63.61  ? 391 ILE B CG2 1 
ATOM   6828  C CD1 . ILE B 1 331 ? -13.158  -29.043 77.683  1.00 72.36  ? 391 ILE B CD1 1 
ATOM   6829  N N   . ALA B 1 332 ? -8.509   -31.407 76.031  1.00 73.02  ? 392 ALA B N   1 
ATOM   6830  C CA  . ALA B 1 332 ? -7.153   -31.884 76.394  1.00 66.64  ? 392 ALA B CA  1 
ATOM   6831  C C   . ALA B 1 332 ? -6.245   -31.885 75.156  1.00 65.40  ? 392 ALA B C   1 
ATOM   6832  O O   . ALA B 1 332 ? -5.136   -31.357 75.218  1.00 60.41  ? 392 ALA B O   1 
ATOM   6833  C CB  . ALA B 1 332 ? -7.236   -33.259 76.994  1.00 63.15  ? 392 ALA B CB  1 
ATOM   6834  N N   . GLU B 1 333 ? -6.711   -32.471 74.064  1.00 66.23  ? 393 GLU B N   1 
ATOM   6835  C CA  . GLU B 1 333 ? -5.920   -32.604 72.819  1.00 74.41  ? 393 GLU B CA  1 
ATOM   6836  C C   . GLU B 1 333 ? -5.578   -31.212 72.267  1.00 65.84  ? 393 GLU B C   1 
ATOM   6837  O O   . GLU B 1 333 ? -4.485   -31.055 71.756  1.00 71.70  ? 393 GLU B O   1 
ATOM   6838  C CB  . GLU B 1 333 ? -6.683   -33.452 71.800  1.00 80.84  ? 393 GLU B CB  1 
ATOM   6839  C CG  . GLU B 1 333 ? -5.866   -33.798 70.565  1.00 83.07  ? 393 GLU B CG  1 
ATOM   6840  C CD  . GLU B 1 333 ? -4.642   -34.669 70.819  1.00 83.42  ? 393 GLU B CD  1 
ATOM   6841  O OE1 . GLU B 1 333 ? -4.632   -35.407 71.816  1.00 78.88  ? 393 GLU B OE1 1 
ATOM   6842  O OE2 . GLU B 1 333 ? -3.704   -34.619 70.013  1.00 79.60  ? 393 GLU B OE2 1 
ATOM   6843  N N   . LEU B 1 334 ? -6.484   -30.244 72.356  1.00 63.74  ? 394 LEU B N   1 
ATOM   6844  C CA  . LEU B 1 334 ? -6.235   -28.876 71.842  1.00 64.79  ? 394 LEU B CA  1 
ATOM   6845  C C   . LEU B 1 334 ? -5.265   -28.159 72.783  1.00 68.04  ? 394 LEU B C   1 
ATOM   6846  O O   . LEU B 1 334 ? -4.572   -27.240 72.348  1.00 70.46  ? 394 LEU B O   1 
ATOM   6847  C CB  . LEU B 1 334 ? -7.540   -28.087 71.712  1.00 64.49  ? 394 LEU B CB  1 
ATOM   6848  C CG  . LEU B 1 334 ? -7.399   -26.834 70.852  1.00 68.42  ? 394 LEU B CG  1 
ATOM   6849  C CD1 . LEU B 1 334 ? -7.210   -27.223 69.392  1.00 69.84  ? 394 LEU B CD1 1 
ATOM   6850  C CD2 . LEU B 1 334 ? -8.583   -25.891 71.026  1.00 69.20  ? 394 LEU B CD2 1 
ATOM   6851  N N   . ILE B 1 335 ? -5.209   -28.549 74.047  1.00 76.11  ? 395 ILE B N   1 
ATOM   6852  C CA  . ILE B 1 335 ? -4.273   -27.918 75.021  1.00 79.69  ? 395 ILE B CA  1 
ATOM   6853  C C   . ILE B 1 335 ? -2.862   -28.408 74.695  1.00 70.73  ? 395 ILE B C   1 
ATOM   6854  O O   . ILE B 1 335 ? -1.995   -27.539 74.458  1.00 63.18  ? 395 ILE B O   1 
ATOM   6855  C CB  . ILE B 1 335 ? -4.714   -28.196 76.471  1.00 79.82  ? 395 ILE B CB  1 
ATOM   6856  C CG1 . ILE B 1 335 ? -6.055   -27.512 76.764  1.00 81.26  ? 395 ILE B CG1 1 
ATOM   6857  C CG2 . ILE B 1 335 ? -3.626   -27.763 77.454  1.00 91.34  ? 395 ILE B CG2 1 
ATOM   6858  C CD1 . ILE B 1 335 ? -6.561   -27.686 78.180  1.00 90.00  ? 395 ILE B CD1 1 
ATOM   6859  N N   . ALA B 1 336 ? -2.684   -29.735 74.623  1.00 67.39  ? 396 ALA B N   1 
ATOM   6860  C CA  . ALA B 1 336 ? -1.414   -30.419 74.289  1.00 71.47  ? 396 ALA B CA  1 
ATOM   6861  C C   . ALA B 1 336 ? -0.883   -29.867 72.960  1.00 64.70  ? 396 ALA B C   1 
ATOM   6862  O O   . ALA B 1 336 ? 0.313    -29.586 72.862  1.00 70.17  ? 396 ALA B O   1 
ATOM   6863  C CB  . ALA B 1 336 ? -1.612   -31.922 74.231  1.00 74.27  ? 396 ALA B CB  1 
ATOM   6864  N N   . LEU B 1 337 ? -1.745   -29.687 71.973  1.00 61.54  ? 397 LEU B N   1 
ATOM   6865  C CA  . LEU B 1 337 ? -1.362   -29.114 70.661  1.00 63.18  ? 397 LEU B CA  1 
ATOM   6866  C C   . LEU B 1 337 ? -0.813   -27.695 70.879  1.00 63.86  ? 397 LEU B C   1 
ATOM   6867  O O   . LEU B 1 337 ? 0.270    -27.418 70.384  1.00 71.72  ? 397 LEU B O   1 
ATOM   6868  C CB  . LEU B 1 337 ? -2.586   -29.141 69.738  1.00 65.71  ? 397 LEU B CB  1 
ATOM   6869  C CG  . LEU B 1 337 ? -2.372   -28.796 68.261  1.00 71.80  ? 397 LEU B CG  1 
ATOM   6870  C CD1 . LEU B 1 337 ? -1.197   -29.557 67.662  1.00 77.07  ? 397 LEU B CD1 1 
ATOM   6871  C CD2 . LEU B 1 337 ? -3.640   -29.087 67.462  1.00 75.47  ? 397 LEU B CD2 1 
ATOM   6872  N N   . GLU B 1 338 ? -1.511   -26.829 71.609  1.00 60.58  ? 398 GLU B N   1 
ATOM   6873  C CA  . GLU B 1 338 ? -1.060   -25.434 71.805  1.00 62.04  ? 398 GLU B CA  1 
ATOM   6874  C C   . GLU B 1 338 ? 0.309    -25.435 72.487  1.00 68.59  ? 398 GLU B C   1 
ATOM   6875  O O   . GLU B 1 338 ? 1.134    -24.561 72.130  1.00 81.17  ? 398 GLU B O   1 
ATOM   6876  C CB  . GLU B 1 338 ? -2.041   -24.630 72.634  1.00 64.45  ? 398 GLU B CB  1 
ATOM   6877  C CG  . GLU B 1 338 ? -1.709   -23.145 72.574  1.00 68.94  ? 398 GLU B CG  1 
ATOM   6878  C CD  . GLU B 1 338 ? -1.526   -22.543 71.183  1.00 67.90  ? 398 GLU B CD  1 
ATOM   6879  O OE1 . GLU B 1 338 ? -2.465   -21.913 70.731  1.00 74.22  ? 398 GLU B OE1 1 
ATOM   6880  O OE2 . GLU B 1 338 ? -0.453   -22.643 70.561  1.00 69.50  ? 398 GLU B OE2 1 
ATOM   6881  N N   . ILE B 1 339 ? 0.544    -26.387 73.396  1.00 65.01  ? 399 ILE B N   1 
ATOM   6882  C CA  . ILE B 1 339 ? 1.852    -26.611 74.099  1.00 67.84  ? 399 ILE B CA  1 
ATOM   6883  C C   . ILE B 1 339 ? 2.925    -26.973 73.063  1.00 66.79  ? 399 ILE B C   1 
ATOM   6884  O O   . ILE B 1 339 ? 3.985    -26.311 73.030  1.00 74.58  ? 399 ILE B O   1 
ATOM   6885  C CB  . ILE B 1 339 ? 1.742    -27.684 75.212  1.00 64.59  ? 399 ILE B CB  1 
ATOM   6886  C CG1 . ILE B 1 339 ? 0.980    -27.150 76.433  1.00 70.23  ? 399 ILE B CG1 1 
ATOM   6887  C CG2 . ILE B 1 339 ? 3.108    -28.222 75.597  1.00 57.71  ? 399 ILE B CG2 1 
ATOM   6888  C CD1 . ILE B 1 339 ? 0.687    -28.168 77.507  1.00 67.33  ? 399 ILE B CD1 1 
ATOM   6889  N N   . SER B 1 340 ? 2.643    -27.964 72.226  1.00 66.00  ? 400 SER B N   1 
ATOM   6890  C CA  . SER B 1 340 ? 3.536    -28.420 71.130  1.00 76.79  ? 400 SER B CA  1 
ATOM   6891  C C   . SER B 1 340 ? 3.920    -27.229 70.236  1.00 70.99  ? 400 SER B C   1 
ATOM   6892  O O   . SER B 1 340 ? 5.044    -27.165 69.803  1.00 79.47  ? 400 SER B O   1 
ATOM   6893  C CB  . SER B 1 340 ? 2.891    -29.544 70.337  1.00 80.14  ? 400 SER B CB  1 
ATOM   6894  O OG  . SER B 1 340 ? 3.682    -30.716 70.419  1.00 86.98  ? 400 SER B OG  1 
ATOM   6895  N N   . LYS B 1 341 ? 3.013    -26.305 69.952  1.00 75.47  ? 401 LYS B N   1 
ATOM   6896  C CA  . LYS B 1 341 ? 3.309    -25.157 69.052  1.00 80.52  ? 401 LYS B CA  1 
ATOM   6897  C C   . LYS B 1 341 ? 4.118    -24.112 69.834  1.00 77.67  ? 401 LYS B C   1 
ATOM   6898  O O   . LYS B 1 341 ? 4.835    -23.340 69.204  1.00 81.55  ? 401 LYS B O   1 
ATOM   6899  C CB  . LYS B 1 341 ? 2.023    -24.650 68.374  1.00 81.27  ? 401 LYS B CB  1 
ATOM   6900  C CG  . LYS B 1 341 ? 1.376    -25.657 67.411  1.00 76.79  ? 401 LYS B CG  1 
ATOM   6901  C CD  . LYS B 1 341 ? 0.827    -25.069 66.087  1.00 84.24  ? 401 LYS B CD  1 
ATOM   6902  C CE  . LYS B 1 341 ? 1.122    -25.872 64.826  1.00 82.30  ? 401 LYS B CE  1 
ATOM   6903  N NZ  . LYS B 1 341 ? 1.640    -25.014 63.721  1.00 84.16  ? 401 LYS B NZ  1 
ATOM   6904  N N   . GLN B 1 342 ? 4.057    -24.111 71.160  1.00 73.53  ? 402 GLN B N   1 
ATOM   6905  C CA  . GLN B 1 342 ? 4.742    -23.085 71.994  1.00 83.72  ? 402 GLN B CA  1 
ATOM   6906  C C   . GLN B 1 342 ? 6.128    -23.592 72.429  1.00 79.61  ? 402 GLN B C   1 
ATOM   6907  O O   . GLN B 1 342 ? 7.007    -22.757 72.689  1.00 74.95  ? 402 GLN B O   1 
ATOM   6908  C CB  . GLN B 1 342 ? 3.855    -22.748 73.190  1.00 86.79  ? 402 GLN B CB  1 
ATOM   6909  C CG  . GLN B 1 342 ? 3.377    -21.299 73.255  1.00 87.76  ? 402 GLN B CG  1 
ATOM   6910  C CD  . GLN B 1 342 ? 2.310    -21.181 74.317  1.00 86.36  ? 402 GLN B CD  1 
ATOM   6911  O OE1 . GLN B 1 342 ? 1.242    -21.761 74.170  1.00 87.49  ? 402 GLN B OE1 1 
ATOM   6912  N NE2 . GLN B 1 342 ? 2.562    -20.443 75.399  1.00 76.25  ? 402 GLN B NE2 1 
ATOM   6913  N N   . THR B 1 343 ? 6.309    -24.907 72.527  1.00 85.70  ? 403 THR B N   1 
ATOM   6914  C CA  . THR B 1 343 ? 7.547    -25.555 73.036  1.00 84.34  ? 403 THR B CA  1 
ATOM   6915  C C   . THR B 1 343 ? 8.320    -26.234 71.903  1.00 83.08  ? 403 THR B C   1 
ATOM   6916  O O   . THR B 1 343 ? 9.524    -26.417 72.040  1.00 88.58  ? 403 THR B O   1 
ATOM   6917  C CB  . THR B 1 343 ? 7.229    -26.617 74.092  1.00 80.91  ? 403 THR B CB  1 
ATOM   6918  O OG1 . THR B 1 343 ? 6.509    -27.680 73.452  1.00 80.05  ? 403 THR B OG1 1 
ATOM   6919  C CG2 . THR B 1 343 ? 6.491    -26.043 75.278  1.00 70.59  ? 403 THR B CG2 1 
ATOM   6920  N N   . ASN B 1 344 ? 7.630    -26.641 70.845  1.00 79.04  ? 404 ASN B N   1 
ATOM   6921  C CA  . ASN B 1 344 ? 8.194    -27.388 69.695  1.00 72.58  ? 404 ASN B CA  1 
ATOM   6922  C C   . ASN B 1 344 ? 8.432    -28.840 70.127  1.00 69.11  ? 404 ASN B C   1 
ATOM   6923  O O   . ASN B 1 344 ? 9.092    -29.580 69.377  1.00 59.09  ? 404 ASN B O   1 
ATOM   6924  C CB  . ASN B 1 344 ? 9.438    -26.714 69.103  1.00 72.34  ? 404 ASN B CB  1 
ATOM   6925  C CG  . ASN B 1 344 ? 9.714    -27.165 67.685  1.00 85.36  ? 404 ASN B CG  1 
ATOM   6926  O OD1 . ASN B 1 344 ? 9.040    -26.720 66.760  1.00 81.41  ? 404 ASN B OD1 1 
ATOM   6927  N ND2 . ASN B 1 344 ? 10.674   -28.067 67.506  1.00 88.13  ? 404 ASN B ND2 1 
ATOM   6928  N N   . ALA B 1 345 ? 7.833    -29.279 71.234  1.00 61.20  ? 405 ALA B N   1 
ATOM   6929  C CA  . ALA B 1 345 ? 7.930    -30.693 71.641  1.00 72.88  ? 405 ALA B CA  1 
ATOM   6930  C C   . ALA B 1 345 ? 6.964    -31.540 70.817  1.00 78.31  ? 405 ALA B C   1 
ATOM   6931  O O   . ALA B 1 345 ? 5.993    -31.011 70.275  1.00 79.00  ? 405 ALA B O   1 
ATOM   6932  C CB  . ALA B 1 345 ? 7.666    -30.813 73.114  1.00 79.17  ? 405 ALA B CB  1 
ATOM   6933  N N   . PRO B 1 346 ? 7.219    -32.866 70.680  1.00 89.14  ? 406 PRO B N   1 
ATOM   6934  C CA  . PRO B 1 346 ? 6.234    -33.803 70.130  1.00 92.56  ? 406 PRO B CA  1 
ATOM   6935  C C   . PRO B 1 346 ? 4.958    -33.824 70.978  1.00 88.83  ? 406 PRO B C   1 
ATOM   6936  O O   . PRO B 1 346 ? 5.038    -33.624 72.160  1.00 84.10  ? 406 PRO B O   1 
ATOM   6937  C CB  . PRO B 1 346 ? 6.927    -35.184 70.153  1.00 100.93 ? 406 PRO B CB  1 
ATOM   6938  C CG  . PRO B 1 346 ? 8.410    -34.870 70.275  1.00 101.52 ? 406 PRO B CG  1 
ATOM   6939  C CD  . PRO B 1 346 ? 8.491    -33.538 71.001  1.00 99.04  ? 406 PRO B CD  1 
ATOM   6940  N N   . ILE B 1 347 ? 3.810    -34.073 70.351  1.00 96.03  ? 407 ILE B N   1 
ATOM   6941  C CA  . ILE B 1 347 ? 2.476    -34.028 71.021  1.00 94.24  ? 407 ILE B CA  1 
ATOM   6942  C C   . ILE B 1 347 ? 2.508    -34.994 72.214  1.00 97.39  ? 407 ILE B C   1 
ATOM   6943  O O   . ILE B 1 347 ? 2.145    -34.541 73.310  1.00 102.00 ? 407 ILE B O   1 
ATOM   6944  C CB  . ILE B 1 347 ? 1.320    -34.287 70.019  1.00 85.48  ? 407 ILE B CB  1 
ATOM   6945  C CG1 . ILE B 1 347 ? -0.012   -33.760 70.554  1.00 84.17  ? 407 ILE B CG1 1 
ATOM   6946  C CG2 . ILE B 1 347 ? 1.237    -35.745 69.582  1.00 79.38  ? 407 ILE B CG2 1 
ATOM   6947  C CD1 . ILE B 1 347 ? -0.112   -32.250 70.534  1.00 73.62  ? 407 ILE B CD1 1 
ATOM   6948  N N   . GLU B 1 348 ? 3.031    -36.220 72.036  1.00 93.90  ? 408 GLU B N   1 
ATOM   6949  C CA  . GLU B 1 348 ? 3.018    -37.320 73.040  1.00 88.15  ? 408 GLU B CA  1 
ATOM   6950  C C   . GLU B 1 348 ? 3.782    -36.903 74.305  1.00 79.37  ? 408 GLU B C   1 
ATOM   6951  O O   . GLU B 1 348 ? 3.624    -37.546 75.345  1.00 71.42  ? 408 GLU B O   1 
ATOM   6952  C CB  . GLU B 1 348 ? 3.624    -38.582 72.427  1.00 97.99  ? 408 GLU B CB  1 
ATOM   6953  C CG  . GLU B 1 348 ? 3.970    -39.652 73.445  1.00 108.52 ? 408 GLU B CG  1 
ATOM   6954  C CD  . GLU B 1 348 ? 4.201    -41.036 72.870  1.00 115.87 ? 408 GLU B CD  1 
ATOM   6955  O OE1 . GLU B 1 348 ? 3.532    -41.403 71.879  1.00 116.50 ? 408 GLU B OE1 1 
ATOM   6956  O OE2 . GLU B 1 348 ? 5.039    -41.767 73.437  1.00 127.87 ? 408 GLU B OE2 1 
ATOM   6957  N N   . GLU B 1 349 ? 4.546    -35.825 74.216  1.00 83.88  ? 409 GLU B N   1 
ATOM   6958  C CA  . GLU B 1 349 ? 5.354    -35.271 75.323  1.00 99.40  ? 409 GLU B CA  1 
ATOM   6959  C C   . GLU B 1 349 ? 4.542    -34.167 76.011  1.00 97.34  ? 409 GLU B C   1 
ATOM   6960  O O   . GLU B 1 349 ? 4.844    -33.870 77.158  1.00 102.62 ? 409 GLU B O   1 
ATOM   6961  C CB  . GLU B 1 349 ? 6.666    -34.718 74.735  1.00 114.49 ? 409 GLU B CB  1 
ATOM   6962  C CG  . GLU B 1 349 ? 7.912    -34.880 75.605  1.00 122.92 ? 409 GLU B CG  1 
ATOM   6963  C CD  . GLU B 1 349 ? 8.049    -34.004 76.848  1.00 131.16 ? 409 GLU B CD  1 
ATOM   6964  O OE1 . GLU B 1 349 ? 8.303    -32.766 76.729  1.00 128.18 ? 409 GLU B OE1 1 
ATOM   6965  O OE2 . GLU B 1 349 ? 7.993    -34.587 77.942  1.00 123.78 ? 409 GLU B OE2 1 
ATOM   6966  N N   . CYS B 1 350 ? 3.630    -33.509 75.278  1.00 93.08  ? 410 CYS B N   1 
ATOM   6967  C CA  . CYS B 1 350 ? 2.824    -32.361 75.786  1.00 83.81  ? 410 CYS B CA  1 
ATOM   6968  C C   . CYS B 1 350 ? 1.624    -32.852 76.611  1.00 82.51  ? 410 CYS B C   1 
ATOM   6969  O O   . CYS B 1 350 ? 1.034    -32.014 77.378  1.00 71.86  ? 410 CYS B O   1 
ATOM   6970  C CB  . CYS B 1 350 ? 2.378    -31.478 74.641  1.00 72.97  ? 410 CYS B CB  1 
ATOM   6971  S SG  . CYS B 1 350 ? 3.786    -30.851 73.716  1.00 71.39  ? 410 CYS B SG  1 
ATOM   6972  N N   . ARG B 1 351 ? 1.305    -34.151 76.539  1.00 80.20  ? 411 ARG B N   1 
ATOM   6973  C CA  . ARG B 1 351 ? 0.230    -34.784 77.346  1.00 83.28  ? 411 ARG B CA  1 
ATOM   6974  C C   . ARG B 1 351 ? 0.728    -35.275 78.713  1.00 91.40  ? 411 ARG B C   1 
ATOM   6975  O O   . ARG B 1 351 ? -0.133   -35.625 79.505  1.00 94.57  ? 411 ARG B O   1 
ATOM   6976  C CB  . ARG B 1 351 ? -0.387   -35.976 76.620  1.00 76.48  ? 411 ARG B CB  1 
ATOM   6977  C CG  . ARG B 1 351 ? -0.790   -35.725 75.179  1.00 79.86  ? 411 ARG B CG  1 
ATOM   6978  C CD  . ARG B 1 351 ? -1.595   -36.910 74.652  1.00 86.19  ? 411 ARG B CD  1 
ATOM   6979  N NE  . ARG B 1 351 ? -1.739   -36.862 73.206  1.00 88.89  ? 411 ARG B NE  1 
ATOM   6980  C CZ  . ARG B 1 351 ? -1.066   -37.623 72.343  1.00 88.58  ? 411 ARG B CZ  1 
ATOM   6981  N NH1 . ARG B 1 351 ? -0.225   -38.546 72.780  1.00 94.37  ? 411 ARG B NH1 1 
ATOM   6982  N NH2 . ARG B 1 351 ? -1.240   -37.458 71.043  1.00 84.95  ? 411 ARG B NH2 1 
ATOM   6983  N N   . LYS B 1 352 ? 2.034    -35.284 78.988  1.00 112.98 ? 412 LYS B N   1 
ATOM   6984  C CA  . LYS B 1 352 ? 2.600    -35.735 80.293  1.00 112.88 ? 412 LYS B CA  1 
ATOM   6985  C C   . LYS B 1 352 ? 1.931    -35.014 81.472  1.00 95.65  ? 412 LYS B C   1 
ATOM   6986  O O   . LYS B 1 352 ? 1.726    -35.723 82.481  1.00 89.21  ? 412 LYS B O   1 
ATOM   6987  C CB  . LYS B 1 352 ? 4.132    -35.573 80.368  1.00 133.11 ? 412 LYS B CB  1 
ATOM   6988  C CG  . LYS B 1 352 ? 4.788    -34.461 79.545  1.00 165.40 ? 412 LYS B CG  1 
ATOM   6989  C CD  . LYS B 1 352 ? 4.678    -33.021 80.055  1.00 175.95 ? 412 LYS B CD  1 
ATOM   6990  C CE  . LYS B 1 352 ? 5.798    -32.101 79.589  1.00 162.06 ? 412 LYS B CE  1 
ATOM   6991  N NZ  . LYS B 1 352 ? 6.973    -32.167 80.498  1.00 168.28 ? 412 LYS B NZ  1 
ATOM   6992  N N   . LYS B 1 353 ? 1.579    -33.716 81.318  1.00 94.88  ? 413 LYS B N   1 
ATOM   6993  C CA  . LYS B 1 353 ? 1.042    -32.787 82.351  1.00 99.48  ? 413 LYS B CA  1 
ATOM   6994  C C   . LYS B 1 353 ? -0.504   -32.827 82.482  1.00 94.19  ? 413 LYS B C   1 
ATOM   6995  O O   . LYS B 1 353 ? -1.032   -32.048 83.297  1.00 83.34  ? 413 LYS B O   1 
ATOM   6996  C CB  . LYS B 1 353 ? 1.333    -31.334 81.948  1.00 112.25 ? 413 LYS B CB  1 
ATOM   6997  C CG  . LYS B 1 353 ? 2.758    -30.896 81.656  1.00 115.59 ? 413 LYS B CG  1 
ATOM   6998  C CD  . LYS B 1 353 ? 3.833    -31.241 82.700  1.00 105.60 ? 413 LYS B CD  1 
ATOM   6999  C CE  . LYS B 1 353 ? 3.554    -30.892 84.145  1.00 92.22  ? 413 LYS B CE  1 
ATOM   7000  N NZ  . LYS B 1 353 ? 3.092    -29.489 84.309  1.00 97.33  ? 413 LYS B NZ  1 
ATOM   7001  N N   . VAL B 1 354 ? -1.193   -33.640 81.671  1.00 77.86  ? 414 VAL B N   1 
ATOM   7002  C CA  . VAL B 1 354 ? -2.672   -33.620 81.493  1.00 71.03  ? 414 VAL B CA  1 
ATOM   7003  C C   . VAL B 1 354 ? -3.238   -34.988 81.892  1.00 71.81  ? 414 VAL B C   1 
ATOM   7004  O O   . VAL B 1 354 ? -2.877   -36.004 81.242  1.00 66.36  ? 414 VAL B O   1 
ATOM   7005  C CB  . VAL B 1 354 ? -3.020   -33.264 80.039  1.00 70.39  ? 414 VAL B CB  1 
ATOM   7006  C CG1 . VAL B 1 354 ? -4.517   -33.259 79.793  1.00 65.42  ? 414 VAL B CG1 1 
ATOM   7007  C CG2 . VAL B 1 354 ? -2.428   -31.918 79.654  1.00 74.17  ? 414 VAL B CG2 1 
ATOM   7008  N N   . TRP B 1 355 ? -4.099   -34.978 82.913  1.00 74.40  ? 415 TRP B N   1 
ATOM   7009  C CA  . TRP B 1 355 ? -4.700   -36.173 83.559  1.00 78.38  ? 415 TRP B CA  1 
ATOM   7010  C C   . TRP B 1 355 ? -6.219   -36.052 83.543  1.00 83.11  ? 415 TRP B C   1 
ATOM   7011  O O   . TRP B 1 355 ? -6.716   -34.995 83.998  1.00 79.58  ? 415 TRP B O   1 
ATOM   7012  C CB  . TRP B 1 355 ? -4.225   -36.284 85.009  1.00 86.49  ? 415 TRP B CB  1 
ATOM   7013  C CG  . TRP B 1 355 ? -2.741   -36.293 85.173  1.00 88.23  ? 415 TRP B CG  1 
ATOM   7014  C CD1 . TRP B 1 355 ? -1.919   -35.209 85.254  1.00 89.37  ? 415 TRP B CD1 1 
ATOM   7015  C CD2 . TRP B 1 355 ? -1.903   -37.450 85.310  1.00 90.60  ? 415 TRP B CD2 1 
ATOM   7016  N NE1 . TRP B 1 355 ? -0.622   -35.609 85.421  1.00 84.36  ? 415 TRP B NE1 1 
ATOM   7017  C CE2 . TRP B 1 355 ? -0.582   -36.976 85.448  1.00 84.93  ? 415 TRP B CE2 1 
ATOM   7018  C CE3 . TRP B 1 355 ? -2.141   -38.832 85.320  1.00 95.58  ? 415 TRP B CE3 1 
ATOM   7019  C CZ2 . TRP B 1 355 ? 0.498    -37.838 85.610  1.00 90.17  ? 415 TRP B CZ2 1 
ATOM   7020  C CZ3 . TRP B 1 355 ? -1.067   -39.684 85.486  1.00 97.48  ? 415 TRP B CZ3 1 
ATOM   7021  C CH2 . TRP B 1 355 ? 0.230    -39.186 85.636  1.00 93.23  ? 415 TRP B CH2 1 
ATOM   7022  N N   . LEU B 1 356 ? -6.908   -37.123 83.126  1.00 91.07  ? 416 LEU B N   1 
ATOM   7023  C CA  . LEU B 1 356 ? -8.391   -37.191 83.117  1.00 95.97  ? 416 LEU B CA  1 
ATOM   7024  C C   . LEU B 1 356 ? -8.869   -38.272 84.093  1.00 101.91 ? 416 LEU B C   1 
ATOM   7025  O O   . LEU B 1 356 ? -8.170   -39.320 84.212  1.00 123.08 ? 416 LEU B O   1 
ATOM   7026  C CB  . LEU B 1 356 ? -8.820   -37.469 81.680  1.00 83.70  ? 416 LEU B CB  1 
ATOM   7027  C CG  . LEU B 1 356 ? -8.809   -36.228 80.785  1.00 82.83  ? 416 LEU B CG  1 
ATOM   7028  C CD1 . LEU B 1 356 ? -7.430   -35.818 80.304  1.00 90.20  ? 416 LEU B CD1 1 
ATOM   7029  C CD2 . LEU B 1 356 ? -9.675   -36.467 79.563  1.00 92.50  ? 416 LEU B CD2 1 
ATOM   7030  N N   . VAL B 1 357 ? -9.978   -37.985 84.790  1.00 87.88  ? 417 VAL B N   1 
ATOM   7031  C CA  . VAL B 1 357 ? -10.668  -38.904 85.742  1.00 77.02  ? 417 VAL B CA  1 
ATOM   7032  C C   . VAL B 1 357 ? -12.084  -39.152 85.224  1.00 80.43  ? 417 VAL B C   1 
ATOM   7033  O O   . VAL B 1 357 ? -12.896  -38.175 85.115  1.00 81.77  ? 417 VAL B O   1 
ATOM   7034  C CB  . VAL B 1 357 ? -10.707  -38.328 87.166  1.00 76.92  ? 417 VAL B CB  1 
ATOM   7035  C CG1 . VAL B 1 357 ? -11.396  -39.279 88.135  1.00 77.26  ? 417 VAL B CG1 1 
ATOM   7036  C CG2 . VAL B 1 357 ? -9.317   -37.947 87.660  1.00 74.87  ? 417 VAL B CG2 1 
ATOM   7037  N N   . ASP B 1 358 ? -12.373  -40.426 84.965  1.00 91.30  ? 418 ASP B N   1 
ATOM   7038  C CA  . ASP B 1 358 ? -13.693  -40.914 84.499  1.00 106.98 ? 418 ASP B CA  1 
ATOM   7039  C C   . ASP B 1 358 ? -14.453  -41.533 85.680  1.00 107.44 ? 418 ASP B C   1 
ATOM   7040  O O   . ASP B 1 358 ? -14.000  -41.388 86.843  1.00 109.96 ? 418 ASP B O   1 
ATOM   7041  C CB  . ASP B 1 358 ? -13.493  -41.905 83.350  1.00 112.29 ? 418 ASP B CB  1 
ATOM   7042  C CG  . ASP B 1 358 ? -12.851  -43.213 83.790  1.00 110.83 ? 418 ASP B CG  1 
ATOM   7043  O OD1 . ASP B 1 358 ? -13.595  -44.100 84.217  1.00 128.59 ? 418 ASP B OD1 1 
ATOM   7044  O OD2 . ASP B 1 358 ? -11.628  -43.322 83.760  1.00 103.11 ? 418 ASP B OD2 1 
ATOM   7045  N N   . SER B 1 359 ? -15.573  -42.193 85.361  1.00 111.02 ? 419 SER B N   1 
ATOM   7046  C CA  . SER B 1 359 ? -16.452  -42.986 86.261  1.00 121.59 ? 419 SER B CA  1 
ATOM   7047  C C   . SER B 1 359 ? -15.639  -43.980 87.109  1.00 127.61 ? 419 SER B C   1 
ATOM   7048  O O   . SER B 1 359 ? -15.954  -44.110 88.300  1.00 128.77 ? 419 SER B O   1 
ATOM   7049  C CB  . SER B 1 359 ? -17.535  -43.695 85.448  1.00 117.62 ? 419 SER B CB  1 
ATOM   7050  O OG  . SER B 1 359 ? -17.235  -43.726 84.046  1.00 88.89  ? 419 SER B OG  1 
ATOM   7051  N N   . LYS B 1 360 ? -14.634  -44.636 86.531  1.00 125.25 ? 420 LYS B N   1 
ATOM   7052  C CA  . LYS B 1 360 ? -13.848  -45.735 87.159  1.00 115.07 ? 420 LYS B CA  1 
ATOM   7053  C C   . LYS B 1 360 ? -12.694  -45.145 87.997  1.00 109.57 ? 420 LYS B C   1 
ATOM   7054  O O   . LYS B 1 360 ? -12.114  -45.908 88.775  1.00 107.83 ? 420 LYS B O   1 
ATOM   7055  C CB  . LYS B 1 360 ? -13.300  -46.734 86.120  1.00 113.82 ? 420 LYS B CB  1 
ATOM   7056  C CG  . LYS B 1 360 ? -14.008  -46.827 84.758  1.00 107.70 ? 420 LYS B CG  1 
ATOM   7057  C CD  . LYS B 1 360 ? -15.135  -47.820 84.698  1.00 108.13 ? 420 LYS B CD  1 
ATOM   7058  C CE  . LYS B 1 360 ? -14.742  -49.087 83.970  1.00 107.94 ? 420 LYS B CE  1 
ATOM   7059  N NZ  . LYS B 1 360 ? -15.594  -50.231 84.370  1.00 108.32 ? 420 LYS B NZ  1 
ATOM   7060  N N   . GLY B 1 361 ? -12.397  -43.841 87.845  1.00 116.27 ? 421 GLY B N   1 
ATOM   7061  C CA  . GLY B 1 361 ? -11.304  -43.131 88.548  1.00 108.85 ? 421 GLY B CA  1 
ATOM   7062  C C   . GLY B 1 361 ? -10.271  -42.542 87.584  1.00 101.08 ? 421 GLY B C   1 
ATOM   7063  O O   . GLY B 1 361 ? -10.621  -42.237 86.416  1.00 103.12 ? 421 GLY B O   1 
ATOM   7064  N N   . LEU B 1 362 ? -9.036   -42.346 88.069  1.00 103.75 ? 422 LEU B N   1 
ATOM   7065  C CA  . LEU B 1 362 ? -7.912   -41.749 87.289  1.00 100.93 ? 422 LEU B CA  1 
ATOM   7066  C C   . LEU B 1 362 ? -7.540   -42.706 86.161  1.00 91.20  ? 422 LEU B C   1 
ATOM   7067  O O   . LEU B 1 362 ? -7.342   -43.900 86.434  1.00 100.16 ? 422 LEU B O   1 
ATOM   7068  C CB  . LEU B 1 362 ? -6.705   -41.487 88.201  1.00 97.66  ? 422 LEU B CB  1 
ATOM   7069  C CG  . LEU B 1 362 ? -5.490   -40.829 87.536  1.00 101.05 ? 422 LEU B CG  1 
ATOM   7070  C CD1 . LEU B 1 362 ? -5.838   -39.453 86.968  1.00 103.82 ? 422 LEU B CD1 1 
ATOM   7071  C CD2 . LEU B 1 362 ? -4.326   -40.709 88.519  1.00 93.71  ? 422 LEU B CD2 1 
ATOM   7072  N N   . ILE B 1 363 ? -7.477   -42.188 84.941  1.00 97.91  ? 423 ILE B N   1 
ATOM   7073  C CA  . ILE B 1 363 ? -7.021   -42.936 83.734  1.00 102.47 ? 423 ILE B CA  1 
ATOM   7074  C C   . ILE B 1 363 ? -5.504   -43.121 83.863  1.00 108.66 ? 423 ILE B C   1 
ATOM   7075  O O   . ILE B 1 363 ? -4.744   -42.109 83.840  1.00 104.23 ? 423 ILE B O   1 
ATOM   7076  C CB  . ILE B 1 363 ? -7.433   -42.232 82.421  1.00 101.39 ? 423 ILE B CB  1 
ATOM   7077  C CG1 . ILE B 1 363 ? -8.947   -42.067 82.318  1.00 99.13  ? 423 ILE B CG1 1 
ATOM   7078  C CG2 . ILE B 1 363 ? -6.880   -42.955 81.205  1.00 98.99  ? 423 ILE B CG2 1 
ATOM   7079  C CD1 . ILE B 1 363 ? -9.442   -41.938 80.915  1.00 108.72 ? 423 ILE B CD1 1 
ATOM   7080  N N   . VAL B 1 364 ? -5.099   -44.383 84.000  1.00 121.44 ? 424 VAL B N   1 
ATOM   7081  C CA  . VAL B 1 364 ? -3.685   -44.828 84.178  1.00 112.01 ? 424 VAL B CA  1 
ATOM   7082  C C   . VAL B 1 364 ? -3.417   -45.956 83.183  1.00 118.40 ? 424 VAL B C   1 
ATOM   7083  O O   . VAL B 1 364 ? -4.404   -46.633 82.773  1.00 126.41 ? 424 VAL B O   1 
ATOM   7084  C CB  . VAL B 1 364 ? -3.448   -45.278 85.626  1.00 97.07  ? 424 VAL B CB  1 
ATOM   7085  C CG1 . VAL B 1 364 ? -3.387   -44.064 86.542  1.00 89.66  ? 424 VAL B CG1 1 
ATOM   7086  C CG2 . VAL B 1 364 ? -4.521   -46.269 86.082  1.00 108.46 ? 424 VAL B CG2 1 
ATOM   7087  N N   . ASP B 1 365 ? -2.146   -46.150 82.808  1.00 122.46 ? 425 ASP B N   1 
ATOM   7088  C CA  . ASP B 1 365 ? -1.730   -47.157 81.786  1.00 118.62 ? 425 ASP B CA  1 
ATOM   7089  C C   . ASP B 1 365 ? -1.995   -48.580 82.333  1.00 120.87 ? 425 ASP B C   1 
ATOM   7090  O O   . ASP B 1 365 ? -2.291   -49.455 81.540  1.00 102.90 ? 425 ASP B O   1 
ATOM   7091  C CB  . ASP B 1 365 ? -0.303   -46.880 81.297  1.00 117.18 ? 425 ASP B CB  1 
ATOM   7092  C CG  . ASP B 1 365 ? 0.800    -47.670 81.986  1.00 125.52 ? 425 ASP B CG  1 
ATOM   7093  O OD1 . ASP B 1 365 ? 0.726    -47.852 83.216  1.00 129.08 ? 425 ASP B OD1 1 
ATOM   7094  O OD2 . ASP B 1 365 ? 1.749    -48.061 81.295  1.00 121.35 ? 425 ASP B OD2 1 
ATOM   7095  N N   . SER B 1 366 ? -1.877   -48.761 83.653  1.00 124.43 ? 426 SER B N   1 
ATOM   7096  C CA  . SER B 1 366 ? -1.968   -50.028 84.416  1.00 110.05 ? 426 SER B CA  1 
ATOM   7097  C C   . SER B 1 366 ? -3.215   -50.816 84.009  1.00 118.63 ? 426 SER B C   1 
ATOM   7098  O O   . SER B 1 366 ? -3.182   -52.051 84.200  1.00 133.59 ? 426 SER B O   1 
ATOM   7099  C CB  . SER B 1 366 ? -1.989   -49.810 85.933  1.00 102.39 ? 426 SER B CB  1 
ATOM   7100  O OG  . SER B 1 366 ? -1.244   -48.676 86.375  1.00 113.06 ? 426 SER B OG  1 
ATOM   7101  N N   . ARG B 1 367 ? -4.274   -50.144 83.525  1.00 119.51 ? 427 ARG B N   1 
ATOM   7102  C CA  . ARG B 1 367 ? -5.584   -50.797 83.229  1.00 120.53 ? 427 ARG B CA  1 
ATOM   7103  C C   . ARG B 1 367 ? -5.837   -50.795 81.710  1.00 135.10 ? 427 ARG B C   1 
ATOM   7104  O O   . ARG B 1 367 ? -7.027   -50.871 81.308  1.00 151.97 ? 427 ARG B O   1 
ATOM   7105  C CB  . ARG B 1 367 ? -6.730   -50.147 84.034  1.00 110.06 ? 427 ARG B CB  1 
ATOM   7106  C CG  . ARG B 1 367 ? -6.869   -48.641 83.875  1.00 114.14 ? 427 ARG B CG  1 
ATOM   7107  C CD  . ARG B 1 367 ? -8.323   -48.219 83.882  1.00 110.57 ? 427 ARG B CD  1 
ATOM   7108  N NE  . ARG B 1 367 ? -8.526   -46.882 84.410  1.00 107.40 ? 427 ARG B NE  1 
ATOM   7109  C CZ  . ARG B 1 367 ? -9.708   -46.275 84.464  1.00 102.77 ? 427 ARG B CZ  1 
ATOM   7110  N NH1 . ARG B 1 367 ? -10.798  -46.870 84.013  1.00 105.08 ? 427 ARG B NH1 1 
ATOM   7111  N NH2 . ARG B 1 367 ? -9.830   -45.051 84.951  1.00 92.73  ? 427 ARG B NH2 1 
ATOM   7112  N N   . LYS B 1 368 ? -4.785   -50.784 80.875  1.00 150.88 ? 428 LYS B N   1 
ATOM   7113  C CA  . LYS B 1 368 ? -4.891   -50.807 79.382  1.00 152.20 ? 428 LYS B CA  1 
ATOM   7114  C C   . LYS B 1 368 ? -5.330   -52.186 78.854  1.00 172.33 ? 428 LYS B C   1 
ATOM   7115  O O   . LYS B 1 368 ? -5.793   -52.221 77.695  1.00 180.92 ? 428 LYS B O   1 
ATOM   7116  C CB  . LYS B 1 368 ? -3.550   -50.383 78.753  1.00 140.79 ? 428 LYS B CB  1 
ATOM   7117  C CG  . LYS B 1 368 ? -3.538   -50.187 77.236  1.00 126.48 ? 428 LYS B CG  1 
ATOM   7118  C CD  . LYS B 1 368 ? -2.261   -50.705 76.522  1.00 116.25 ? 428 LYS B CD  1 
ATOM   7119  C CE  . LYS B 1 368 ? -2.219   -52.219 76.427  1.00 104.00 ? 428 LYS B CE  1 
ATOM   7120  N NZ  . LYS B 1 368 ? -0.832   -52.741 76.449  1.00 95.35  ? 428 LYS B NZ  1 
ATOM   7121  N N   . GLY B 1 369 ? -5.247   -53.249 79.677  1.00 184.63 ? 429 GLY B N   1 
ATOM   7122  C CA  . GLY B 1 369 ? -5.708   -54.617 79.357  1.00 176.51 ? 429 GLY B CA  1 
ATOM   7123  C C   . GLY B 1 369 ? -7.227   -54.726 79.210  1.00 172.82 ? 429 GLY B C   1 
ATOM   7124  O O   . GLY B 1 369 ? -7.704   -55.874 79.045  1.00 150.64 ? 429 GLY B O   1 
ATOM   7125  N N   . SER B 1 370 ? -7.957   -53.597 79.298  1.00 159.27 ? 430 SER B N   1 
ATOM   7126  C CA  . SER B 1 370 ? -9.381   -53.440 78.871  1.00 136.29 ? 430 SER B CA  1 
ATOM   7127  C C   . SER B 1 370 ? -9.760   -51.947 78.914  1.00 134.60 ? 430 SER B C   1 
ATOM   7128  O O   . SER B 1 370 ? -10.696  -51.565 79.644  1.00 128.31 ? 430 SER B O   1 
ATOM   7129  C CB  . SER B 1 370 ? -10.324  -54.314 79.675  1.00 123.34 ? 430 SER B CB  1 
ATOM   7130  O OG  . SER B 1 370 ? -10.012  -54.279 81.057  1.00 117.65 ? 430 SER B OG  1 
ATOM   7131  N N   . LEU B 1 371 ? -9.059   -51.130 78.127  1.00 131.73 ? 431 LEU B N   1 
ATOM   7132  C CA  . LEU B 1 371 ? -9.277   -49.659 78.031  1.00 139.61 ? 431 LEU B CA  1 
ATOM   7133  C C   . LEU B 1 371 ? -10.043  -49.337 76.748  1.00 155.40 ? 431 LEU B C   1 
ATOM   7134  O O   . LEU B 1 371 ? -9.998   -50.177 75.820  1.00 176.24 ? 431 LEU B O   1 
ATOM   7135  C CB  . LEU B 1 371 ? -7.922   -48.952 77.999  1.00 142.22 ? 431 LEU B CB  1 
ATOM   7136  C CG  . LEU B 1 371 ? -7.628   -48.012 79.164  1.00 146.44 ? 431 LEU B CG  1 
ATOM   7137  C CD1 . LEU B 1 371 ? -6.238   -47.416 79.029  1.00 156.77 ? 431 LEU B CD1 1 
ATOM   7138  C CD2 . LEU B 1 371 ? -8.665   -46.905 79.243  1.00 128.29 ? 431 LEU B CD2 1 
ATOM   7139  N N   . GLN B 1 372 ? -10.708  -48.181 76.691  1.00 139.44 ? 432 GLN B N   1 
ATOM   7140  C CA  . GLN B 1 372 ? -11.326  -47.681 75.429  1.00 132.04 ? 432 GLN B CA  1 
ATOM   7141  C C   . GLN B 1 372 ? -10.192  -47.035 74.631  1.00 146.94 ? 432 GLN B C   1 
ATOM   7142  O O   . GLN B 1 372 ? -9.273   -46.476 75.231  1.00 143.63 ? 432 GLN B O   1 
ATOM   7143  C CB  . GLN B 1 372 ? -12.527  -46.771 75.723  1.00 120.29 ? 432 GLN B CB  1 
ATOM   7144  C CG  . GLN B 1 372 ? -13.717  -47.457 76.408  1.00 103.87 ? 432 GLN B CG  1 
ATOM   7145  C CD  . GLN B 1 372 ? -13.767  -47.457 77.926  1.00 92.55  ? 432 GLN B CD  1 
ATOM   7146  O OE1 . GLN B 1 372 ? -12.783  -47.251 78.644  1.00 83.41  ? 432 GLN B OE1 1 
ATOM   7147  N NE2 . GLN B 1 372 ? -14.936  -47.774 78.441  1.00 81.63  ? 432 GLN B NE2 1 
ATOM   7148  N N   . PRO B 1 373 ? -10.174  -47.118 73.270  1.00 156.82 ? 433 PRO B N   1 
ATOM   7149  C CA  . PRO B 1 373 ? -9.024   -46.666 72.485  1.00 141.64 ? 433 PRO B CA  1 
ATOM   7150  C C   . PRO B 1 373 ? -8.699   -45.171 72.633  1.00 132.25 ? 433 PRO B C   1 
ATOM   7151  O O   . PRO B 1 373 ? -7.548   -44.872 72.788  1.00 121.22 ? 433 PRO B O   1 
ATOM   7152  C CB  . PRO B 1 373 ? -9.412   -46.979 71.032  1.00 133.75 ? 433 PRO B CB  1 
ATOM   7153  C CG  . PRO B 1 373 ? -10.422  -48.085 71.168  1.00 145.77 ? 433 PRO B CG  1 
ATOM   7154  C CD  . PRO B 1 373 ? -11.206  -47.722 72.419  1.00 158.07 ? 433 PRO B CD  1 
ATOM   7155  N N   . PHE B 1 374 ? -9.695   -44.276 72.596  1.00 119.50 ? 434 PHE B N   1 
ATOM   7156  C CA  . PHE B 1 374 ? -9.469   -42.801 72.530  1.00 104.01 ? 434 PHE B CA  1 
ATOM   7157  C C   . PHE B 1 374 ? -9.076   -42.215 73.890  1.00 93.75  ? 434 PHE B C   1 
ATOM   7158  O O   . PHE B 1 374 ? -9.016   -40.968 73.982  1.00 88.49  ? 434 PHE B O   1 
ATOM   7159  C CB  . PHE B 1 374 ? -10.713  -42.098 71.997  1.00 113.73 ? 434 PHE B CB  1 
ATOM   7160  C CG  . PHE B 1 374 ? -11.828  -41.822 72.977  1.00 113.09 ? 434 PHE B CG  1 
ATOM   7161  C CD1 . PHE B 1 374 ? -12.564  -42.840 73.577  1.00 104.50 ? 434 PHE B CD1 1 
ATOM   7162  C CD2 . PHE B 1 374 ? -12.150  -40.507 73.278  1.00 109.87 ? 434 PHE B CD2 1 
ATOM   7163  C CE1 . PHE B 1 374 ? -13.613  -42.539 74.435  1.00 100.55 ? 434 PHE B CE1 1 
ATOM   7164  C CE2 . PHE B 1 374 ? -13.215  -40.210 74.121  1.00 112.34 ? 434 PHE B CE2 1 
ATOM   7165  C CZ  . PHE B 1 374 ? -13.936  -41.227 74.708  1.00 103.10 ? 434 PHE B CZ  1 
ATOM   7166  N N   . LYS B 1 375 ? -8.859   -43.077 74.890  1.00 91.88  ? 435 LYS B N   1 
ATOM   7167  C CA  . LYS B 1 375 ? -8.419   -42.709 76.265  1.00 94.93  ? 435 LYS B CA  1 
ATOM   7168  C C   . LYS B 1 375 ? -6.920   -43.008 76.469  1.00 115.59 ? 435 LYS B C   1 
ATOM   7169  O O   . LYS B 1 375 ? -6.278   -42.345 77.328  1.00 121.31 ? 435 LYS B O   1 
ATOM   7170  C CB  . LYS B 1 375 ? -9.271   -43.469 77.286  1.00 98.23  ? 435 LYS B CB  1 
ATOM   7171  C CG  . LYS B 1 375 ? -10.636  -42.836 77.569  1.00 107.21 ? 435 LYS B CG  1 
ATOM   7172  C CD  . LYS B 1 375 ? -11.663  -43.782 78.172  1.00 104.90 ? 435 LYS B CD  1 
ATOM   7173  C CE  . LYS B 1 375 ? -12.703  -43.129 79.056  1.00 104.90 ? 435 LYS B CE  1 
ATOM   7174  N NZ  . LYS B 1 375 ? -13.710  -44.122 79.490  1.00 103.02 ? 435 LYS B NZ  1 
ATOM   7175  N N   . LYS B 1 376 ? -6.387   -43.984 75.722  1.00 126.41 ? 436 LYS B N   1 
ATOM   7176  C CA  . LYS B 1 376 ? -5.000   -44.519 75.859  1.00 113.69 ? 436 LYS B CA  1 
ATOM   7177  C C   . LYS B 1 376 ? -3.980   -43.384 75.799  1.00 99.74  ? 436 LYS B C   1 
ATOM   7178  O O   . LYS B 1 376 ? -3.022   -43.413 76.561  1.00 91.91  ? 436 LYS B O   1 
ATOM   7179  C CB  . LYS B 1 376 ? -4.711   -45.586 74.799  1.00 113.04 ? 436 LYS B CB  1 
ATOM   7180  C CG  . LYS B 1 376 ? -5.293   -46.964 75.119  1.00 111.02 ? 436 LYS B CG  1 
ATOM   7181  C CD  . LYS B 1 376 ? -4.913   -48.030 74.133  1.00 112.97 ? 436 LYS B CD  1 
ATOM   7182  C CE  . LYS B 1 376 ? -6.008   -49.056 73.897  1.00 103.24 ? 436 LYS B CE  1 
ATOM   7183  N NZ  . LYS B 1 376 ? -5.505   -50.203 73.114  1.00 100.37 ? 436 LYS B NZ  1 
ATOM   7184  N N   . PRO B 1 377 ? -4.113   -42.363 74.925  1.00 90.02  ? 437 PRO B N   1 
ATOM   7185  C CA  . PRO B 1 377 ? -3.190   -41.229 74.926  1.00 92.26  ? 437 PRO B CA  1 
ATOM   7186  C C   . PRO B 1 377 ? -3.108   -40.419 76.227  1.00 88.05  ? 437 PRO B C   1 
ATOM   7187  O O   . PRO B 1 377 ? -2.233   -39.594 76.324  1.00 106.23 ? 437 PRO B O   1 
ATOM   7188  C CB  . PRO B 1 377 ? -3.703   -40.279 73.833  1.00 94.47  ? 437 PRO B CB  1 
ATOM   7189  C CG  . PRO B 1 377 ? -4.695   -41.077 73.012  1.00 94.51  ? 437 PRO B CG  1 
ATOM   7190  C CD  . PRO B 1 377 ? -5.074   -42.293 73.824  1.00 97.04  ? 437 PRO B CD  1 
ATOM   7191  N N   . TRP B 1 378 ? -4.008   -40.653 77.176  1.00 78.49  ? 438 TRP B N   1 
ATOM   7192  C CA  . TRP B 1 378 ? -4.018   -39.913 78.462  1.00 71.33  ? 438 TRP B CA  1 
ATOM   7193  C C   . TRP B 1 378 ? -3.653   -40.835 79.627  1.00 69.09  ? 438 TRP B C   1 
ATOM   7194  O O   . TRP B 1 378 ? -3.455   -40.323 80.756  1.00 66.02  ? 438 TRP B O   1 
ATOM   7195  C CB  . TRP B 1 378 ? -5.376   -39.237 78.613  1.00 69.35  ? 438 TRP B CB  1 
ATOM   7196  C CG  . TRP B 1 378 ? -5.750   -38.484 77.372  1.00 67.25  ? 438 TRP B CG  1 
ATOM   7197  C CD1 . TRP B 1 378 ? -6.615   -38.888 76.397  1.00 60.17  ? 438 TRP B CD1 1 
ATOM   7198  C CD2 . TRP B 1 378 ? -5.226   -37.209 76.949  1.00 69.54  ? 438 TRP B CD2 1 
ATOM   7199  N NE1 . TRP B 1 378 ? -6.694   -37.935 75.420  1.00 68.51  ? 438 TRP B NE1 1 
ATOM   7200  C CE2 . TRP B 1 378 ? -5.857   -36.889 75.728  1.00 70.16  ? 438 TRP B CE2 1 
ATOM   7201  C CE3 . TRP B 1 378 ? -4.302   -36.299 77.488  1.00 67.88  ? 438 TRP B CE3 1 
ATOM   7202  C CZ2 . TRP B 1 378 ? -5.593   -35.702 75.040  1.00 62.92  ? 438 TRP B CZ2 1 
ATOM   7203  C CZ3 . TRP B 1 378 ? -4.038   -35.135 76.802  1.00 60.44  ? 438 TRP B CZ3 1 
ATOM   7204  C CH2 . TRP B 1 378 ? -4.656   -34.859 75.587  1.00 60.03  ? 438 TRP B CH2 1 
ATOM   7205  N N   . ALA B 1 379 ? -3.482   -42.125 79.329  1.00 78.35  ? 439 ALA B N   1 
ATOM   7206  C CA  . ALA B 1 379 ? -3.128   -43.215 80.270  1.00 83.03  ? 439 ALA B CA  1 
ATOM   7207  C C   . ALA B 1 379 ? -1.636   -43.161 80.613  1.00 87.87  ? 439 ALA B C   1 
ATOM   7208  O O   . ALA B 1 379 ? -0.886   -44.073 80.219  1.00 89.73  ? 439 ALA B O   1 
ATOM   7209  C CB  . ALA B 1 379 ? -3.496   -44.541 79.644  1.00 81.72  ? 439 ALA B CB  1 
ATOM   7210  N N   . HIS B 1 380 ? -1.223   -42.129 81.343  1.00 102.24 ? 440 HIS B N   1 
ATOM   7211  C CA  . HIS B 1 380 ? 0.177    -41.958 81.809  1.00 107.08 ? 440 HIS B CA  1 
ATOM   7212  C C   . HIS B 1 380 ? 0.470    -43.014 82.887  1.00 109.64 ? 440 HIS B C   1 
ATOM   7213  O O   . HIS B 1 380 ? -0.353   -43.955 83.041  1.00 107.77 ? 440 HIS B O   1 
ATOM   7214  C CB  . HIS B 1 380 ? 0.406    -40.510 82.273  1.00 97.84  ? 440 HIS B CB  1 
ATOM   7215  C CG  . HIS B 1 380 ? -0.149   -39.508 81.328  1.00 97.99  ? 440 HIS B CG  1 
ATOM   7216  N ND1 . HIS B 1 380 ? 0.075    -39.595 79.970  1.00 86.96  ? 440 HIS B ND1 1 
ATOM   7217  C CD2 . HIS B 1 380 ? -0.945   -38.437 81.536  1.00 104.48 ? 440 HIS B CD2 1 
ATOM   7218  C CE1 . HIS B 1 380 ? -0.555   -38.605 79.379  1.00 94.71  ? 440 HIS B CE1 1 
ATOM   7219  N NE2 . HIS B 1 380 ? -1.202   -37.888 80.316  1.00 108.19 ? 440 HIS B NE2 1 
ATOM   7220  N N   . GLU B 1 381 ? 1.563    -42.780 83.623  1.00 114.74 ? 441 GLU B N   1 
ATOM   7221  C CA  . GLU B 1 381 ? 2.232    -43.659 84.609  1.00 109.30 ? 441 GLU B CA  1 
ATOM   7222  C C   . GLU B 1 381 ? 1.813    -43.252 86.019  1.00 107.84 ? 441 GLU B C   1 
ATOM   7223  O O   . GLU B 1 381 ? 2.205    -42.165 86.428  1.00 129.88 ? 441 GLU B O   1 
ATOM   7224  C CB  . GLU B 1 381 ? 3.739    -43.420 84.501  1.00 112.94 ? 441 GLU B CB  1 
ATOM   7225  C CG  . GLU B 1 381 ? 4.372    -43.869 83.201  1.00 121.59 ? 441 GLU B CG  1 
ATOM   7226  C CD  . GLU B 1 381 ? 4.536    -42.824 82.097  1.00 125.02 ? 441 GLU B CD  1 
ATOM   7227  O OE1 . GLU B 1 381 ? 3.766    -41.827 82.081  1.00 136.86 ? 441 GLU B OE1 1 
ATOM   7228  O OE2 . GLU B 1 381 ? 5.450    -42.999 81.249  1.00 90.89  ? 441 GLU B OE2 1 
ATOM   7229  N N   . HIS B 1 382 ? 1.099    -44.118 86.745  1.00 96.61  ? 442 HIS B N   1 
ATOM   7230  C CA  . HIS B 1 382 ? 0.461    -43.889 88.077  1.00 96.38  ? 442 HIS B CA  1 
ATOM   7231  C C   . HIS B 1 382 ? -0.298   -45.172 88.422  1.00 102.91 ? 442 HIS B C   1 
ATOM   7232  O O   . HIS B 1 382 ? -0.608   -45.945 87.468  1.00 94.13  ? 442 HIS B O   1 
ATOM   7233  C CB  . HIS B 1 382 ? -0.527   -42.714 88.076  1.00 104.79 ? 442 HIS B CB  1 
ATOM   7234  C CG  . HIS B 1 382 ? -0.183   -41.583 88.982  1.00 112.22 ? 442 HIS B CG  1 
ATOM   7235  N ND1 . HIS B 1 382 ? 0.743    -40.613 88.651  1.00 128.21 ? 442 HIS B ND1 1 
ATOM   7236  C CD2 . HIS B 1 382 ? -0.635   -41.275 90.217  1.00 117.92 ? 442 HIS B CD2 1 
ATOM   7237  C CE1 . HIS B 1 382 ? 0.844    -39.748 89.642  1.00 126.25 ? 442 HIS B CE1 1 
ATOM   7238  N NE2 . HIS B 1 382 ? -0.008   -40.116 90.607  1.00 107.66 ? 442 HIS B NE2 1 
ATOM   7239  N N   . GLU B 1 383 ? -0.602   -45.439 89.693  1.00 111.42 ? 443 GLU B N   1 
ATOM   7240  C CA  . GLU B 1 383 ? -1.341   -46.698 90.020  1.00 138.03 ? 443 GLU B CA  1 
ATOM   7241  C C   . GLU B 1 383 ? -2.757   -46.257 90.403  1.00 136.23 ? 443 GLU B C   1 
ATOM   7242  O O   . GLU B 1 383 ? -2.902   -45.164 90.949  1.00 114.70 ? 443 GLU B O   1 
ATOM   7243  C CB  . GLU B 1 383 ? -0.551   -47.575 91.020  1.00 156.48 ? 443 GLU B CB  1 
ATOM   7244  C CG  . GLU B 1 383 ? -0.247   -49.025 90.551  1.00 158.14 ? 443 GLU B CG  1 
ATOM   7245  C CD  . GLU B 1 383 ? 0.832    -49.307 89.490  1.00 158.87 ? 443 GLU B CD  1 
ATOM   7246  O OE1 . GLU B 1 383 ? 0.970    -48.527 88.527  1.00 161.11 ? 443 GLU B OE1 1 
ATOM   7247  O OE2 . GLU B 1 383 ? 1.536    -50.329 89.608  1.00 124.14 ? 443 GLU B OE2 1 
ATOM   7248  N N   . PRO B 1 384 ? -3.815   -47.058 90.082  1.00 155.34 ? 444 PRO B N   1 
ATOM   7249  C CA  . PRO B 1 384 ? -5.209   -46.628 90.141  1.00 155.98 ? 444 PRO B CA  1 
ATOM   7250  C C   . PRO B 1 384 ? -5.545   -45.799 91.379  1.00 141.23 ? 444 PRO B C   1 
ATOM   7251  O O   . PRO B 1 384 ? -5.236   -46.205 92.445  1.00 139.79 ? 444 PRO B O   1 
ATOM   7252  C CB  . PRO B 1 384 ? -5.999   -47.957 90.138  1.00 151.78 ? 444 PRO B CB  1 
ATOM   7253  C CG  . PRO B 1 384 ? -5.185   -48.819 89.231  1.00 151.20 ? 444 PRO B CG  1 
ATOM   7254  C CD  . PRO B 1 384 ? -3.756   -48.417 89.518  1.00 156.55 ? 444 PRO B CD  1 
ATOM   7255  N N   . LEU B 1 385 ? -6.120   -44.612 91.171  1.00 121.17 ? 445 LEU B N   1 
ATOM   7256  C CA  . LEU B 1 385 ? -6.777   -43.777 92.218  1.00 112.20 ? 445 LEU B CA  1 
ATOM   7257  C C   . LEU B 1 385 ? -8.289   -43.754 91.955  1.00 112.40 ? 445 LEU B C   1 
ATOM   7258  O O   . LEU B 1 385 ? -8.670   -43.778 90.772  1.00 120.03 ? 445 LEU B O   1 
ATOM   7259  C CB  . LEU B 1 385 ? -6.204   -42.365 92.151  1.00 112.07 ? 445 LEU B CB  1 
ATOM   7260  C CG  . LEU B 1 385 ? -4.758   -42.183 92.608  1.00 115.18 ? 445 LEU B CG  1 
ATOM   7261  C CD1 . LEU B 1 385 ? -4.552   -40.788 93.167  1.00 100.32 ? 445 LEU B CD1 1 
ATOM   7262  C CD2 . LEU B 1 385 ? -4.345   -43.231 93.630  1.00 122.19 ? 445 LEU B CD2 1 
ATOM   7263  N N   . LYS B 1 386 ? -9.106   -43.746 93.012  1.00 111.13 ? 446 LYS B N   1 
ATOM   7264  C CA  . LYS B 1 386 ? -10.540  -44.146 92.964  1.00 103.84 ? 446 LYS B CA  1 
ATOM   7265  C C   . LYS B 1 386 ? -11.413  -42.921 92.700  1.00 97.22  ? 446 LYS B C   1 
ATOM   7266  O O   . LYS B 1 386 ? -12.263  -43.000 91.829  1.00 114.44 ? 446 LYS B O   1 
ATOM   7267  C CB  . LYS B 1 386 ? -11.001  -44.788 94.277  1.00 105.54 ? 446 LYS B CB  1 
ATOM   7268  C CG  . LYS B 1 386 ? -11.084  -46.312 94.301  1.00 103.30 ? 446 LYS B CG  1 
ATOM   7269  C CD  . LYS B 1 386 ? -11.583  -46.838 95.652  1.00 105.74 ? 446 LYS B CD  1 
ATOM   7270  C CE  . LYS B 1 386 ? -11.742  -48.344 95.729  1.00 98.84  ? 446 LYS B CE  1 
ATOM   7271  N NZ  . LYS B 1 386 ? -12.558  -48.847 94.604  1.00 86.94  ? 446 LYS B NZ  1 
ATOM   7272  N N   . THR B 1 387 ? -11.207  -41.833 93.436  1.00 83.19  ? 447 THR B N   1 
ATOM   7273  C CA  . THR B 1 387 ? -12.101  -40.649 93.425  1.00 76.53  ? 447 THR B CA  1 
ATOM   7274  C C   . THR B 1 387 ? -11.347  -39.420 92.930  1.00 72.19  ? 447 THR B C   1 
ATOM   7275  O O   . THR B 1 387 ? -10.110  -39.406 93.072  1.00 72.96  ? 447 THR B O   1 
ATOM   7276  C CB  . THR B 1 387 ? -12.612  -40.345 94.832  1.00 89.20  ? 447 THR B CB  1 
ATOM   7277  O OG1 . THR B 1 387 ? -11.440  -40.093 95.619  1.00 86.50  ? 447 THR B OG1 1 
ATOM   7278  C CG2 . THR B 1 387 ? -13.485  -41.453 95.385  1.00 97.02  ? 447 THR B CG2 1 
ATOM   7279  N N   . LEU B 1 388 ? -12.083  -38.415 92.442  1.00 71.88  ? 448 LEU B N   1 
ATOM   7280  C CA  . LEU B 1 388 ? -11.510  -37.109 92.016  1.00 73.98  ? 448 LEU B CA  1 
ATOM   7281  C C   . LEU B 1 388 ? -10.752  -36.517 93.200  1.00 67.31  ? 448 LEU B C   1 
ATOM   7282  O O   . LEU B 1 388 ? -9.685   -35.956 92.980  1.00 73.97  ? 448 LEU B O   1 
ATOM   7283  C CB  . LEU B 1 388 ? -12.590  -36.141 91.521  1.00 80.34  ? 448 LEU B CB  1 
ATOM   7284  C CG  . LEU B 1 388 ? -12.106  -34.710 91.250  1.00 82.00  ? 448 LEU B CG  1 
ATOM   7285  C CD1 . LEU B 1 388 ? -11.061  -34.667 90.130  1.00 76.96  ? 448 LEU B CD1 1 
ATOM   7286  C CD2 . LEU B 1 388 ? -13.275  -33.762 90.934  1.00 85.90  ? 448 LEU B CD2 1 
ATOM   7287  N N   . TYR B 1 389 ? -11.273  -36.642 94.414  1.00 69.96  ? 449 TYR B N   1 
ATOM   7288  C CA  . TYR B 1 389 ? -10.573  -36.092 95.604  1.00 76.10  ? 449 TYR B CA  1 
ATOM   7289  C C   . TYR B 1 389 ? -9.166   -36.679 95.738  1.00 84.73  ? 449 TYR B C   1 
ATOM   7290  O O   . TYR B 1 389 ? -8.210   -35.902 96.001  1.00 109.39 ? 449 TYR B O   1 
ATOM   7291  C CB  . TYR B 1 389 ? -11.320  -36.291 96.915  1.00 72.50  ? 449 TYR B CB  1 
ATOM   7292  C CG  . TYR B 1 389 ? -10.686  -35.483 98.013  1.00 73.63  ? 449 TYR B CG  1 
ATOM   7293  C CD1 . TYR B 1 389 ? -10.772  -34.092 98.022  1.00 72.77  ? 449 TYR B CD1 1 
ATOM   7294  C CD2 . TYR B 1 389 ? -9.953   -36.094 99.010  1.00 80.13  ? 449 TYR B CD2 1 
ATOM   7295  C CE1 . TYR B 1 389 ? -10.194  -33.336 99.024  1.00 73.80  ? 449 TYR B CE1 1 
ATOM   7296  C CE2 . TYR B 1 389 ? -9.374   -35.349 100.031 1.00 80.38  ? 449 TYR B CE2 1 
ATOM   7297  C CZ  . TYR B 1 389 ? -9.504   -33.967 100.044 1.00 72.30  ? 449 TYR B CZ  1 
ATOM   7298  O OH  . TYR B 1 389 ? -8.952   -33.223 101.048 1.00 55.44  ? 449 TYR B OH  1 
ATOM   7299  N N   . ASP B 1 390 ? -9.016   -37.984 95.502  1.00 92.24  ? 450 ASP B N   1 
ATOM   7300  C CA  . ASP B 1 390 ? -7.708   -38.686 95.607  1.00 87.42  ? 450 ASP B CA  1 
ATOM   7301  C C   . ASP B 1 390 ? -6.756   -38.149 94.536  1.00 91.27  ? 450 ASP B C   1 
ATOM   7302  O O   . ASP B 1 390 ? -5.587   -37.803 94.851  1.00 87.03  ? 450 ASP B O   1 
ATOM   7303  C CB  . ASP B 1 390 ? -7.868   -40.195 95.453  1.00 81.69  ? 450 ASP B CB  1 
ATOM   7304  C CG  . ASP B 1 390 ? -8.515   -40.835 96.659  1.00 84.79  ? 450 ASP B CG  1 
ATOM   7305  O OD1 . ASP B 1 390 ? -8.752   -40.121 97.651  1.00 86.73  ? 450 ASP B OD1 1 
ATOM   7306  O OD2 . ASP B 1 390 ? -8.773   -42.032 96.599  1.00 85.76  ? 450 ASP B OD2 1 
ATOM   7307  N N   . ALA B 1 391 ? -7.243   -38.098 93.301  1.00 87.61  ? 451 ALA B N   1 
ATOM   7308  C CA  . ALA B 1 391 ? -6.487   -37.529 92.169  1.00 84.30  ? 451 ALA B CA  1 
ATOM   7309  C C   . ALA B 1 391 ? -6.099   -36.087 92.509  1.00 70.37  ? 451 ALA B C   1 
ATOM   7310  O O   . ALA B 1 391 ? -4.915   -35.783 92.372  1.00 80.43  ? 451 ALA B O   1 
ATOM   7311  C CB  . ALA B 1 391 ? -7.271   -37.629 90.879  1.00 95.84  ? 451 ALA B CB  1 
ATOM   7312  N N   . VAL B 1 392 ? -7.020   -35.227 92.965  1.00 62.50  ? 452 VAL B N   1 
ATOM   7313  C CA  . VAL B 1 392 ? -6.707   -33.771 93.126  1.00 58.08  ? 452 VAL B CA  1 
ATOM   7314  C C   . VAL B 1 392 ? -5.506   -33.685 94.060  1.00 69.77  ? 452 VAL B C   1 
ATOM   7315  O O   . VAL B 1 392 ? -4.607   -32.844 93.814  1.00 69.32  ? 452 VAL B O   1 
ATOM   7316  C CB  . VAL B 1 392 ? -7.896   -32.944 93.641  1.00 57.42  ? 452 VAL B CB  1 
ATOM   7317  C CG1 . VAL B 1 392 ? -7.474   -31.582 94.178  1.00 57.76  ? 452 VAL B CG1 1 
ATOM   7318  C CG2 . VAL B 1 392 ? -8.935   -32.758 92.557  1.00 63.66  ? 452 VAL B CG2 1 
ATOM   7319  N N   . GLN B 1 393 ? -5.464   -34.558 95.071  1.00 80.63  ? 453 GLN B N   1 
ATOM   7320  C CA  . GLN B 1 393 ? -4.445   -34.466 96.146  1.00 81.44  ? 453 GLN B CA  1 
ATOM   7321  C C   . GLN B 1 393 ? -3.111   -35.026 95.626  1.00 87.77  ? 453 GLN B C   1 
ATOM   7322  O O   . GLN B 1 393 ? -2.074   -34.407 95.956  1.00 90.34  ? 453 GLN B O   1 
ATOM   7323  C CB  . GLN B 1 393 ? -4.935   -35.128 97.429  1.00 75.52  ? 453 GLN B CB  1 
ATOM   7324  C CG  . GLN B 1 393 ? -4.488   -34.360 98.672  1.00 83.83  ? 453 GLN B CG  1 
ATOM   7325  C CD  . GLN B 1 393 ? -5.455   -33.279 99.114  1.00 93.64  ? 453 GLN B CD  1 
ATOM   7326  O OE1 . GLN B 1 393 ? -6.529   -33.591 99.629  1.00 109.01 ? 453 GLN B OE1 1 
ATOM   7327  N NE2 . GLN B 1 393 ? -5.068   -32.006 98.990  1.00 81.08  ? 453 GLN B NE2 1 
ATOM   7328  N N   . SER B 1 394 ? -3.135   -36.111 94.836  1.00 83.06  ? 454 SER B N   1 
ATOM   7329  C CA  . SER B 1 394 ? -1.921   -36.800 94.315  1.00 76.58  ? 454 SER B CA  1 
ATOM   7330  C C   . SER B 1 394 ? -1.306   -35.982 93.169  1.00 85.53  ? 454 SER B C   1 
ATOM   7331  O O   . SER B 1 394 ? -0.118   -35.653 93.250  1.00 97.98  ? 454 SER B O   1 
ATOM   7332  C CB  . SER B 1 394 ? -2.240   -38.228 93.897  1.00 85.46  ? 454 SER B CB  1 
ATOM   7333  O OG  . SER B 1 394 ? -1.099   -38.899 93.353  1.00 75.43  ? 454 SER B OG  1 
ATOM   7334  N N   . ILE B 1 395 ? -2.095   -35.638 92.146  1.00 100.99 ? 455 ILE B N   1 
ATOM   7335  C CA  . ILE B 1 395 ? -1.631   -34.930 90.911  1.00 94.03  ? 455 ILE B CA  1 
ATOM   7336  C C   . ILE B 1 395 ? -1.294   -33.473 91.244  1.00 88.86  ? 455 ILE B C   1 
ATOM   7337  O O   . ILE B 1 395 ? -0.440   -32.905 90.556  1.00 81.01  ? 455 ILE B O   1 
ATOM   7338  C CB  . ILE B 1 395 ? -2.670   -35.014 89.777  1.00 89.25  ? 455 ILE B CB  1 
ATOM   7339  C CG1 . ILE B 1 395 ? -2.657   -36.399 89.102  1.00 89.21  ? 455 ILE B CG1 1 
ATOM   7340  C CG2 . ILE B 1 395 ? -2.499   -33.845 88.791  1.00 81.78  ? 455 ILE B CG2 1 
ATOM   7341  C CD1 . ILE B 1 395 ? -1.297   -36.881 88.639  1.00 95.13  ? 455 ILE B CD1 1 
ATOM   7342  N N   . LYS B 1 396 ? -1.951   -32.887 92.240  1.00 83.84  ? 456 LYS B N   1 
ATOM   7343  C CA  . LYS B 1 396 ? -1.585   -31.540 92.721  1.00 82.84  ? 456 LYS B CA  1 
ATOM   7344  C C   . LYS B 1 396 ? -1.755   -30.538 91.589  1.00 72.47  ? 456 LYS B C   1 
ATOM   7345  O O   . LYS B 1 396 ? -0.871   -29.728 91.374  1.00 66.77  ? 456 LYS B O   1 
ATOM   7346  C CB  . LYS B 1 396 ? -0.104   -31.631 93.126  1.00 102.25 ? 456 LYS B CB  1 
ATOM   7347  C CG  . LYS B 1 396 ? 0.348    -30.890 94.377  1.00 116.90 ? 456 LYS B CG  1 
ATOM   7348  C CD  . LYS B 1 396 ? -0.236   -31.431 95.664  1.00 115.33 ? 456 LYS B CD  1 
ATOM   7349  C CE  . LYS B 1 396 ? -1.168   -30.438 96.324  1.00 123.11 ? 456 LYS B CE  1 
ATOM   7350  N NZ  . LYS B 1 396 ? -2.310   -29.989 95.473  1.00 120.27 ? 456 LYS B NZ  1 
ATOM   7351  N N   . PRO B 1 397 ? -2.878   -30.545 90.838  1.00 79.78  ? 457 PRO B N   1 
ATOM   7352  C CA  . PRO B 1 397 ? -2.989   -29.760 89.609  1.00 74.95  ? 457 PRO B CA  1 
ATOM   7353  C C   . PRO B 1 397 ? -3.029   -28.227 89.807  1.00 66.86  ? 457 PRO B C   1 
ATOM   7354  O O   . PRO B 1 397 ? -3.346   -27.745 90.857  1.00 49.55  ? 457 PRO B O   1 
ATOM   7355  C CB  . PRO B 1 397 ? -4.323   -30.274 89.044  1.00 74.39  ? 457 PRO B CB  1 
ATOM   7356  C CG  . PRO B 1 397 ? -5.136   -30.630 90.249  1.00 74.70  ? 457 PRO B CG  1 
ATOM   7357  C CD  . PRO B 1 397 ? -4.123   -31.243 91.186  1.00 78.51  ? 457 PRO B CD  1 
ATOM   7358  N N   . THR B 1 398 ? -2.711   -27.499 88.742  1.00 70.41  ? 458 THR B N   1 
ATOM   7359  C CA  . THR B 1 398 ? -2.769   -26.023 88.592  1.00 73.34  ? 458 THR B CA  1 
ATOM   7360  C C   . THR B 1 398 ? -4.143   -25.615 88.059  1.00 75.11  ? 458 THR B C   1 
ATOM   7361  O O   . THR B 1 398 ? -4.586   -24.458 88.307  1.00 68.43  ? 458 THR B O   1 
ATOM   7362  C CB  . THR B 1 398 ? -1.818   -25.603 87.462  1.00 70.94  ? 458 THR B CB  1 
ATOM   7363  O OG1 . THR B 1 398 ? -0.440   -25.683 87.831  1.00 81.64  ? 458 THR B OG1 1 
ATOM   7364  C CG2 . THR B 1 398 ? -2.020   -24.176 87.011  1.00 80.65  ? 458 THR B CG2 1 
ATOM   7365  N N   . VAL B 1 399 ? -4.736   -26.533 87.283  1.00 69.58  ? 459 VAL B N   1 
ATOM   7366  C CA  . VAL B 1 399 ? -5.991   -26.315 86.511  1.00 72.22  ? 459 VAL B CA  1 
ATOM   7367  C C   . VAL B 1 399 ? -6.903   -27.529 86.691  1.00 65.49  ? 459 VAL B C   1 
ATOM   7368  O O   . VAL B 1 399 ? -6.484   -28.672 86.321  1.00 52.68  ? 459 VAL B O   1 
ATOM   7369  C CB  . VAL B 1 399 ? -5.691   -26.073 85.022  1.00 75.86  ? 459 VAL B CB  1 
ATOM   7370  C CG1 . VAL B 1 399 ? -6.973   -25.880 84.238  1.00 80.49  ? 459 VAL B CG1 1 
ATOM   7371  C CG2 . VAL B 1 399 ? -4.752   -24.898 84.809  1.00 77.38  ? 459 VAL B CG2 1 
ATOM   7372  N N   . LEU B 1 400 ? -8.109   -27.259 87.205  1.00 63.73  ? 460 LEU B N   1 
ATOM   7373  C CA  . LEU B 1 400 ? -9.177   -28.260 87.418  1.00 66.94  ? 460 LEU B CA  1 
ATOM   7374  C C   . LEU B 1 400 ? -10.352  -27.923 86.497  1.00 69.60  ? 460 LEU B C   1 
ATOM   7375  O O   . LEU B 1 400 ? -11.002  -26.891 86.724  1.00 73.07  ? 460 LEU B O   1 
ATOM   7376  C CB  . LEU B 1 400 ? -9.608   -28.231 88.883  1.00 62.86  ? 460 LEU B CB  1 
ATOM   7377  C CG  . LEU B 1 400 ? -10.690  -29.243 89.257  1.00 60.90  ? 460 LEU B CG  1 
ATOM   7378  C CD1 . LEU B 1 400 ? -10.155  -30.670 89.160  1.00 57.66  ? 460 LEU B CD1 1 
ATOM   7379  C CD2 . LEU B 1 400 ? -11.218  -28.948 90.642  1.00 57.79  ? 460 LEU B CD2 1 
ATOM   7380  N N   . ILE B 1 401 ? -10.594  -28.780 85.506  1.00 69.43  ? 461 ILE B N   1 
ATOM   7381  C CA  . ILE B 1 401 ? -11.660  -28.625 84.482  1.00 67.49  ? 461 ILE B CA  1 
ATOM   7382  C C   . ILE B 1 401 ? -12.677  -29.762 84.653  1.00 70.20  ? 461 ILE B C   1 
ATOM   7383  O O   . ILE B 1 401 ? -12.285  -30.944 84.695  1.00 70.14  ? 461 ILE B O   1 
ATOM   7384  C CB  . ILE B 1 401 ? -11.051  -28.612 83.072  1.00 75.36  ? 461 ILE B CB  1 
ATOM   7385  C CG1 . ILE B 1 401 ? -10.185  -27.375 82.829  1.00 77.87  ? 461 ILE B CG1 1 
ATOM   7386  C CG2 . ILE B 1 401 ? -12.152  -28.701 82.040  1.00 81.10  ? 461 ILE B CG2 1 
ATOM   7387  C CD1 . ILE B 1 401 ? -9.354   -27.436 81.557  1.00 75.11  ? 461 ILE B CD1 1 
ATOM   7388  N N   . GLY B 1 402 ? -13.951  -29.401 84.751  1.00 78.52  ? 462 GLY B N   1 
ATOM   7389  C CA  . GLY B 1 402 ? -15.061  -30.353 84.893  1.00 79.14  ? 462 GLY B CA  1 
ATOM   7390  C C   . GLY B 1 402 ? -15.884  -30.428 83.622  1.00 81.26  ? 462 GLY B C   1 
ATOM   7391  O O   . GLY B 1 402 ? -16.501  -29.396 83.207  1.00 75.48  ? 462 GLY B O   1 
ATOM   7392  N N   . THR B 1 403 ? -15.920  -31.617 83.027  1.00 79.81  ? 463 THR B N   1 
ATOM   7393  C CA  . THR B 1 403 ? -16.756  -31.935 81.845  1.00 75.67  ? 463 THR B CA  1 
ATOM   7394  C C   . THR B 1 403 ? -17.536  -33.220 82.141  1.00 73.45  ? 463 THR B C   1 
ATOM   7395  O O   . THR B 1 403 ? -17.594  -34.069 81.266  1.00 66.39  ? 463 THR B O   1 
ATOM   7396  C CB  . THR B 1 403 ? -15.859  -32.037 80.602  1.00 77.39  ? 463 THR B CB  1 
ATOM   7397  O OG1 . THR B 1 403 ? -14.801  -32.964 80.873  1.00 71.57  ? 463 THR B OG1 1 
ATOM   7398  C CG2 . THR B 1 403 ? -15.273  -30.705 80.182  1.00 69.11  ? 463 THR B CG2 1 
ATOM   7399  N N   . SER B 1 404 ? -18.101  -33.361 83.345  1.00 81.13  ? 464 SER B N   1 
ATOM   7400  C CA  . SER B 1 404 ? -18.647  -34.642 83.881  1.00 78.77  ? 464 SER B CA  1 
ATOM   7401  C C   . SER B 1 404 ? -20.094  -34.834 83.457  1.00 66.40  ? 464 SER B C   1 
ATOM   7402  O O   . SER B 1 404 ? -20.527  -35.978 83.385  1.00 62.89  ? 464 SER B O   1 
ATOM   7403  C CB  . SER B 1 404 ? -18.542  -34.694 85.390  1.00 84.13  ? 464 SER B CB  1 
ATOM   7404  O OG  . SER B 1 404 ? -18.734  -33.407 85.969  1.00 64.32  ? 464 SER B OG  1 
ATOM   7405  N N   . GLY B 1 405 ? -20.810  -33.729 83.264  1.00 79.20  ? 465 GLY B N   1 
ATOM   7406  C CA  . GLY B 1 405 ? -22.281  -33.687 83.127  1.00 84.29  ? 465 GLY B CA  1 
ATOM   7407  C C   . GLY B 1 405 ? -22.996  -33.869 84.464  1.00 81.92  ? 465 GLY B C   1 
ATOM   7408  O O   . GLY B 1 405 ? -24.233  -34.076 84.451  1.00 79.24  ? 465 GLY B O   1 
ATOM   7409  N N   . VAL B 1 406 ? -22.262  -33.775 85.585  1.00 74.30  ? 466 VAL B N   1 
ATOM   7410  C CA  . VAL B 1 406 ? -22.771  -34.061 86.955  1.00 61.91  ? 466 VAL B CA  1 
ATOM   7411  C C   . VAL B 1 406 ? -22.550  -32.825 87.823  1.00 55.29  ? 466 VAL B C   1 
ATOM   7412  O O   . VAL B 1 406 ? -21.424  -32.334 87.924  1.00 51.88  ? 466 VAL B O   1 
ATOM   7413  C CB  . VAL B 1 406 ? -22.100  -35.296 87.580  1.00 66.28  ? 466 VAL B CB  1 
ATOM   7414  C CG1 . VAL B 1 406 ? -22.784  -35.664 88.884  1.00 72.71  ? 466 VAL B CG1 1 
ATOM   7415  C CG2 . VAL B 1 406 ? -22.073  -36.489 86.638  1.00 67.41  ? 466 VAL B CG2 1 
ATOM   7416  N N   . GLY B 1 407 ? -23.610  -32.356 88.453  1.00 63.47  ? 467 GLY B N   1 
ATOM   7417  C CA  . GLY B 1 407 ? -23.578  -31.131 89.258  1.00 70.86  ? 467 GLY B CA  1 
ATOM   7418  C C   . GLY B 1 407 ? -22.910  -31.386 90.583  1.00 74.88  ? 467 GLY B C   1 
ATOM   7419  O O   . GLY B 1 407 ? -22.945  -32.543 91.058  1.00 68.68  ? 467 GLY B O   1 
ATOM   7420  N N   . ARG B 1 408 ? -22.287  -30.344 91.129  1.00 87.39  ? 468 ARG B N   1 
ATOM   7421  C CA  . ARG B 1 408 ? -21.829  -30.269 92.536  1.00 88.66  ? 468 ARG B CA  1 
ATOM   7422  C C   . ARG B 1 408 ? -20.865  -31.451 92.825  1.00 84.07  ? 468 ARG B C   1 
ATOM   7423  O O   . ARG B 1 408 ? -20.912  -32.019 93.933  1.00 86.48  ? 468 ARG B O   1 
ATOM   7424  C CB  . ARG B 1 408 ? -23.104  -30.126 93.374  1.00 82.47  ? 468 ARG B CB  1 
ATOM   7425  C CG  . ARG B 1 408 ? -24.029  -29.004 92.904  1.00 77.70  ? 468 ARG B CG  1 
ATOM   7426  C CD  . ARG B 1 408 ? -24.468  -28.143 94.088  1.00 98.61  ? 468 ARG B CD  1 
ATOM   7427  N NE  . ARG B 1 408 ? -25.419  -27.028 93.872  1.00 108.12 ? 468 ARG B NE  1 
ATOM   7428  C CZ  . ARG B 1 408 ? -26.002  -26.293 94.850  1.00 81.82  ? 468 ARG B CZ  1 
ATOM   7429  N NH1 . ARG B 1 408 ? -25.745  -26.535 96.126  1.00 75.85  ? 468 ARG B NH1 1 
ATOM   7430  N NH2 . ARG B 1 408 ? -26.857  -25.327 94.553  1.00 59.40  ? 468 ARG B NH2 1 
ATOM   7431  N N   . THR B 1 409 ? -19.995  -31.794 91.863  1.00 80.37  ? 469 THR B N   1 
ATOM   7432  C CA  . THR B 1 409 ? -18.900  -32.807 91.998  1.00 76.00  ? 469 THR B CA  1 
ATOM   7433  C C   . THR B 1 409 ? -17.576  -32.127 92.380  1.00 67.79  ? 469 THR B C   1 
ATOM   7434  O O   . THR B 1 409 ? -16.649  -32.830 92.863  1.00 62.40  ? 469 THR B O   1 
ATOM   7435  C CB  . THR B 1 409 ? -18.719  -33.627 90.713  1.00 71.87  ? 469 THR B CB  1 
ATOM   7436  O OG1 . THR B 1 409 ? -18.684  -32.697 89.635  1.00 81.36  ? 469 THR B OG1 1 
ATOM   7437  C CG2 . THR B 1 409 ? -19.816  -34.646 90.492  1.00 67.45  ? 469 THR B CG2 1 
ATOM   7438  N N   . PHE B 1 410 ? -17.489  -30.812 92.142  1.00 72.41  ? 470 PHE B N   1 
ATOM   7439  C CA  . PHE B 1 410 ? -16.463  -29.893 92.706  1.00 65.05  ? 470 PHE B CA  1 
ATOM   7440  C C   . PHE B 1 410 ? -16.965  -29.431 94.073  1.00 72.43  ? 470 PHE B C   1 
ATOM   7441  O O   . PHE B 1 410 ? -17.683  -28.424 94.150  1.00 74.17  ? 470 PHE B O   1 
ATOM   7442  C CB  . PHE B 1 410 ? -16.150  -28.729 91.767  1.00 56.95  ? 470 PHE B CB  1 
ATOM   7443  C CG  . PHE B 1 410 ? -15.402  -29.110 90.514  1.00 53.16  ? 470 PHE B CG  1 
ATOM   7444  C CD1 . PHE B 1 410 ? -15.183  -30.455 90.180  1.00 46.94  ? 470 PHE B CD1 1 
ATOM   7445  C CD2 . PHE B 1 410 ? -14.965  -28.115 89.645  1.00 50.55  ? 470 PHE B CD2 1 
ATOM   7446  C CE1 . PHE B 1 410 ? -14.518  -30.800 89.015  1.00 46.09  ? 470 PHE B CE1 1 
ATOM   7447  C CE2 . PHE B 1 410 ? -14.306  -28.459 88.474  1.00 53.93  ? 470 PHE B CE2 1 
ATOM   7448  C CZ  . PHE B 1 410 ? -14.080  -29.800 88.171  1.00 53.45  ? 470 PHE B CZ  1 
ATOM   7449  N N   . THR B 1 411 ? -16.592  -30.220 95.097  1.00 88.67  ? 471 THR B N   1 
ATOM   7450  C CA  . THR B 1 411 ? -17.028  -30.158 96.521  1.00 65.88  ? 471 THR B CA  1 
ATOM   7451  C C   . THR B 1 411 ? -16.162  -29.120 97.243  1.00 61.00  ? 471 THR B C   1 
ATOM   7452  O O   . THR B 1 411 ? -15.175  -28.675 96.668  1.00 63.37  ? 471 THR B O   1 
ATOM   7453  C CB  . THR B 1 411 ? -16.992  -31.573 97.120  1.00 58.53  ? 471 THR B CB  1 
ATOM   7454  O OG1 . THR B 1 411 ? -15.648  -32.050 97.108  1.00 60.55  ? 471 THR B OG1 1 
ATOM   7455  C CG2 . THR B 1 411 ? -17.829  -32.564 96.341  1.00 58.30  ? 471 THR B CG2 1 
ATOM   7456  N N   . LYS B 1 412 ? -16.539  -28.747 98.462  1.00 73.41  ? 472 LYS B N   1 
ATOM   7457  C CA  . LYS B 1 412 ? -15.790  -27.828 99.359  1.00 82.00  ? 472 LYS B CA  1 
ATOM   7458  C C   . LYS B 1 412 ? -14.377  -28.404 99.572  1.00 91.14  ? 472 LYS B C   1 
ATOM   7459  O O   . LYS B 1 412 ? -13.416  -27.633 99.408  1.00 97.68  ? 472 LYS B O   1 
ATOM   7460  C CB  . LYS B 1 412 ? -16.631  -27.632 100.639 1.00 83.63  ? 472 LYS B CB  1 
ATOM   7461  C CG  . LYS B 1 412 ? -16.284  -26.478 101.575 1.00 80.79  ? 472 LYS B CG  1 
ATOM   7462  C CD  . LYS B 1 412 ? -16.526  -26.748 103.073 1.00 89.30  ? 472 LYS B CD  1 
ATOM   7463  C CE  . LYS B 1 412 ? -15.329  -27.404 103.748 1.00 100.36 ? 472 LYS B CE  1 
ATOM   7464  N NZ  . LYS B 1 412 ? -15.466  -27.489 105.224 1.00 95.57  ? 472 LYS B NZ  1 
ATOM   7465  N N   . GLU B 1 413 ? -14.245  -29.705 99.868  1.00 92.96  ? 473 GLU B N   1 
ATOM   7466  C CA  . GLU B 1 413 ? -12.944  -30.417 100.065 1.00 91.19  ? 473 GLU B CA  1 
ATOM   7467  C C   . GLU B 1 413 ? -12.030  -30.247 98.851  1.00 85.65  ? 473 GLU B C   1 
ATOM   7468  O O   . GLU B 1 413 ? -10.804  -30.061 99.056  1.00 97.30  ? 473 GLU B O   1 
ATOM   7469  C CB  . GLU B 1 413 ? -13.149  -31.917 100.243 1.00 99.56  ? 473 GLU B CB  1 
ATOM   7470  C CG  . GLU B 1 413 ? -13.845  -32.241 101.547 1.00 117.71 ? 473 GLU B CG  1 
ATOM   7471  C CD  . GLU B 1 413 ? -14.841  -33.384 101.454 1.00 130.81 ? 473 GLU B CD  1 
ATOM   7472  O OE1 . GLU B 1 413 ? -14.619  -34.315 100.624 1.00 131.98 ? 473 GLU B OE1 1 
ATOM   7473  O OE2 . GLU B 1 413 ? -15.842  -33.340 102.216 1.00 134.75 ? 473 GLU B OE2 1 
ATOM   7474  N N   . ILE B 1 414 ? -12.610  -30.357 97.655  1.00 68.75  ? 474 ILE B N   1 
ATOM   7475  C CA  . ILE B 1 414 ? -11.873  -30.289 96.367  1.00 67.31  ? 474 ILE B CA  1 
ATOM   7476  C C   . ILE B 1 414 ? -11.430  -28.843 96.111  1.00 61.91  ? 474 ILE B C   1 
ATOM   7477  O O   . ILE B 1 414 ? -10.228  -28.645 95.910  1.00 57.41  ? 474 ILE B O   1 
ATOM   7478  C CB  . ILE B 1 414 ? -12.734  -30.838 95.214  1.00 71.46  ? 474 ILE B CB  1 
ATOM   7479  C CG1 . ILE B 1 414 ? -13.088  -32.322 95.386  1.00 75.28  ? 474 ILE B CG1 1 
ATOM   7480  C CG2 . ILE B 1 414 ? -12.066  -30.514 93.891  1.00 69.08  ? 474 ILE B CG2 1 
ATOM   7481  C CD1 . ILE B 1 414 ? -12.818  -33.243 94.218  1.00 69.84  ? 474 ILE B CD1 1 
ATOM   7482  N N   . ILE B 1 415 ? -12.340  -27.866 96.149  1.00 57.72  ? 475 ILE B N   1 
ATOM   7483  C CA  . ILE B 1 415 ? -12.007  -26.422 95.959  1.00 63.99  ? 475 ILE B CA  1 
ATOM   7484  C C   . ILE B 1 415 ? -11.033  -25.982 97.055  1.00 66.13  ? 475 ILE B C   1 
ATOM   7485  O O   . ILE B 1 415 ? -10.158  -25.151 96.754  1.00 64.17  ? 475 ILE B O   1 
ATOM   7486  C CB  . ILE B 1 415 ? -13.249  -25.498 96.015  1.00 70.01  ? 475 ILE B CB  1 
ATOM   7487  C CG1 . ILE B 1 415 ? -14.350  -25.855 95.021  1.00 72.94  ? 475 ILE B CG1 1 
ATOM   7488  C CG2 . ILE B 1 415 ? -12.822  -24.041 95.912  1.00 65.92  ? 475 ILE B CG2 1 
ATOM   7489  C CD1 . ILE B 1 415 ? -13.837  -26.126 93.655  1.00 83.24  ? 475 ILE B CD1 1 
ATOM   7490  N N   . GLU B 1 416 ? -11.225  -26.448 98.293  1.00 70.04  ? 476 GLU B N   1 
ATOM   7491  C CA  . GLU B 1 416 ? -10.351  -26.070 99.431  1.00 73.83  ? 476 GLU B CA  1 
ATOM   7492  C C   . GLU B 1 416 ? -8.958   -26.659 99.196  1.00 75.51  ? 476 GLU B C   1 
ATOM   7493  O O   . GLU B 1 416 ? -7.985   -25.898 99.314  1.00 78.91  ? 476 GLU B O   1 
ATOM   7494  C CB  . GLU B 1 416 ? -10.955  -26.492 100.775 1.00 76.84  ? 476 GLU B CB  1 
ATOM   7495  C CG  . GLU B 1 416 ? -11.970  -25.479 101.301 1.00 83.95  ? 476 GLU B CG  1 
ATOM   7496  C CD  . GLU B 1 416 ? -12.124  -25.392 102.810 1.00 91.80  ? 476 GLU B CD  1 
ATOM   7497  O OE1 . GLU B 1 416 ? -12.105  -26.472 103.459 1.00 93.66  ? 476 GLU B OE1 1 
ATOM   7498  O OE2 . GLU B 1 416 ? -12.243  -24.243 103.324 1.00 86.43  ? 476 GLU B OE2 1 
ATOM   7499  N N   . ALA B 1 417 ? -8.869   -27.947 98.849  1.00 78.21  ? 477 ALA B N   1 
ATOM   7500  C CA  . ALA B 1 417 ? -7.614   -28.645 98.479  1.00 65.60  ? 477 ALA B CA  1 
ATOM   7501  C C   . ALA B 1 417 ? -6.886   -27.830 97.424  1.00 58.70  ? 477 ALA B C   1 
ATOM   7502  O O   . ALA B 1 417 ? -5.719   -27.521 97.647  1.00 76.94  ? 477 ALA B O   1 
ATOM   7503  C CB  . ALA B 1 417 ? -7.894   -30.041 97.971  1.00 69.78  ? 477 ALA B CB  1 
ATOM   7504  N N   . MET B 1 418 ? -7.568   -27.485 96.330  1.00 64.41  ? 478 MET B N   1 
ATOM   7505  C CA  . MET B 1 418 ? -7.010   -26.700 95.188  1.00 65.88  ? 478 MET B CA  1 
ATOM   7506  C C   . MET B 1 418 ? -6.562   -25.309 95.644  1.00 62.92  ? 478 MET B C   1 
ATOM   7507  O O   . MET B 1 418 ? -5.604   -24.809 95.053  1.00 67.23  ? 478 MET B O   1 
ATOM   7508  C CB  . MET B 1 418 ? -8.044   -26.516 94.076  1.00 73.38  ? 478 MET B CB  1 
ATOM   7509  C CG  . MET B 1 418 ? -8.385   -27.827 93.340  1.00 75.48  ? 478 MET B CG  1 
ATOM   7510  S SD  . MET B 1 418 ? -7.222   -28.267 92.019  1.00 77.83  ? 478 MET B SD  1 
ATOM   7511  C CE  . MET B 1 418 ? -6.864   -26.643 91.329  1.00 74.00  ? 478 MET B CE  1 
ATOM   7512  N N   . SER B 1 419 ? -7.244   -24.694 96.615  1.00 60.50  ? 479 SER B N   1 
ATOM   7513  C CA  . SER B 1 419 ? -6.953   -23.325 97.121  1.00 63.42  ? 479 SER B CA  1 
ATOM   7514  C C   . SER B 1 419 ? -5.752   -23.364 98.060  1.00 65.62  ? 479 SER B C   1 
ATOM   7515  O O   . SER B 1 419 ? -5.138   -22.294 98.275  1.00 58.30  ? 479 SER B O   1 
ATOM   7516  C CB  . SER B 1 419 ? -8.150   -22.725 97.816  1.00 65.96  ? 479 SER B CB  1 
ATOM   7517  O OG  . SER B 1 419 ? -9.311   -22.802 96.995  1.00 67.17  ? 479 SER B OG  1 
ATOM   7518  N N   . SER B 1 420 ? -5.440   -24.553 98.584  1.00 76.62  ? 480 SER B N   1 
ATOM   7519  C CA  . SER B 1 420 ? -4.404   -24.796 99.625  1.00 80.86  ? 480 SER B CA  1 
ATOM   7520  C C   . SER B 1 420 ? -2.993   -24.819 99.006  1.00 82.43  ? 480 SER B C   1 
ATOM   7521  O O   . SER B 1 420 ? -2.091   -24.221 99.600  1.00 78.97  ? 480 SER B O   1 
ATOM   7522  C CB  . SER B 1 420 ? -4.711   -26.059 100.423 1.00 84.10  ? 480 SER B CB  1 
ATOM   7523  O OG  . SER B 1 420 ? -4.060   -27.216 99.907  1.00 72.32  ? 480 SER B OG  1 
ATOM   7524  N N   . PHE B 1 421 ? -2.794   -25.459 97.847  1.00 87.79  ? 481 PHE B N   1 
ATOM   7525  C CA  . PHE B 1 421 ? -1.468   -25.646 97.208  1.00 97.36  ? 481 PHE B CA  1 
ATOM   7526  C C   . PHE B 1 421 ? -1.231   -24.616 96.107  1.00 82.70  ? 481 PHE B C   1 
ATOM   7527  O O   . PHE B 1 421 ? -0.104   -24.205 95.957  1.00 107.73 ? 481 PHE B O   1 
ATOM   7528  C CB  . PHE B 1 421 ? -1.350   -27.110 96.786  1.00 115.29 ? 481 PHE B CB  1 
ATOM   7529  C CG  . PHE B 1 421 ? -1.371   -28.043 97.976  1.00 164.56 ? 481 PHE B CG  1 
ATOM   7530  C CD1 . PHE B 1 421 ? -0.322   -28.017 98.888  1.00 181.47 ? 481 PHE B CD1 1 
ATOM   7531  C CD2 . PHE B 1 421 ? -2.428   -28.925 98.214  1.00 203.09 ? 481 PHE B CD2 1 
ATOM   7532  C CE1 . PHE B 1 421 ? -0.311   -28.857 99.993  1.00 186.53 ? 481 PHE B CE1 1 
ATOM   7533  C CE2 . PHE B 1 421 ? -2.414   -29.759 99.322  1.00 212.58 ? 481 PHE B CE2 1 
ATOM   7534  C CZ  . PHE B 1 421 ? -1.352   -29.733 100.203 1.00 199.77 ? 481 PHE B CZ  1 
ATOM   7535  N N   . ASN B 1 422 ? -2.249   -24.213 95.364  1.00 75.12  ? 482 ASN B N   1 
ATOM   7536  C CA  . ASN B 1 422 ? -2.185   -23.064 94.427  1.00 77.18  ? 482 ASN B CA  1 
ATOM   7537  C C   . ASN B 1 422 ? -2.586   -21.795 95.184  1.00 76.19  ? 482 ASN B C   1 
ATOM   7538  O O   . ASN B 1 422 ? -3.465   -21.883 96.070  1.00 70.79  ? 482 ASN B O   1 
ATOM   7539  C CB  . ASN B 1 422 ? -3.088   -23.280 93.210  1.00 83.10  ? 482 ASN B CB  1 
ATOM   7540  C CG  . ASN B 1 422 ? -2.820   -24.603 92.525  1.00 73.12  ? 482 ASN B CG  1 
ATOM   7541  O OD1 . ASN B 1 422 ? -3.588   -25.541 92.651  1.00 65.08  ? 482 ASN B OD1 1 
ATOM   7542  N ND2 . ASN B 1 422 ? -1.688   -24.708 91.870  1.00 74.13  ? 482 ASN B ND2 1 
ATOM   7543  N N   . GLU B 1 423 ? -1.994   -20.656 94.832  1.00 76.74  ? 483 GLU B N   1 
ATOM   7544  C CA  . GLU B 1 423 ? -2.378   -19.352 95.429  1.00 76.70  ? 483 GLU B CA  1 
ATOM   7545  C C   . GLU B 1 423 ? -3.583   -18.810 94.670  1.00 80.01  ? 483 GLU B C   1 
ATOM   7546  O O   . GLU B 1 423 ? -4.414   -18.190 95.319  1.00 82.81  ? 483 GLU B O   1 
ATOM   7547  C CB  . GLU B 1 423 ? -1.244   -18.331 95.456  1.00 84.44  ? 483 GLU B CB  1 
ATOM   7548  C CG  . GLU B 1 423 ? -0.756   -17.986 96.855  1.00 99.34  ? 483 GLU B CG  1 
ATOM   7549  C CD  . GLU B 1 423 ? -1.769   -17.395 97.832  1.00 110.16 ? 483 GLU B CD  1 
ATOM   7550  O OE1 . GLU B 1 423 ? -2.609   -16.552 97.422  1.00 102.76 ? 483 GLU B OE1 1 
ATOM   7551  O OE2 . GLU B 1 423 ? -1.683   -17.748 99.034  1.00 116.27 ? 483 GLU B OE2 1 
ATOM   7552  N N   . ARG B 1 424 ? -3.669   -19.020 93.351  1.00 82.42  ? 484 ARG B N   1 
ATOM   7553  C CA  . ARG B 1 424 ? -4.848   -18.639 92.515  1.00 76.76  ? 484 ARG B CA  1 
ATOM   7554  C C   . ARG B 1 424 ? -5.232   -19.824 91.630  1.00 65.88  ? 484 ARG B C   1 
ATOM   7555  O O   . ARG B 1 424 ? -4.830   -19.852 90.477  1.00 69.28  ? 484 ARG B O   1 
ATOM   7556  C CB  . ARG B 1 424 ? -4.523   -17.359 91.730  1.00 75.03  ? 484 ARG B CB  1 
ATOM   7557  C CG  . ARG B 1 424 ? -4.229   -16.203 92.685  1.00 73.71  ? 484 ARG B CG  1 
ATOM   7558  C CD  . ARG B 1 424 ? -3.886   -14.852 92.115  1.00 78.09  ? 484 ARG B CD  1 
ATOM   7559  N NE  . ARG B 1 424 ? -4.875   -13.812 91.888  1.00 73.99  ? 484 ARG B NE  1 
ATOM   7560  C CZ  . ARG B 1 424 ? -6.190   -13.907 91.973  1.00 75.52  ? 484 ARG B CZ  1 
ATOM   7561  N NH1 . ARG B 1 424 ? -6.775   -15.009 92.384  1.00 73.59  ? 484 ARG B NH1 1 
ATOM   7562  N NH2 . ARG B 1 424 ? -6.917   -12.843 91.685  1.00 82.28  ? 484 ARG B NH2 1 
ATOM   7563  N N   . PRO B 1 425 ? -5.951   -20.856 92.139  1.00 64.85  ? 485 PRO B N   1 
ATOM   7564  C CA  . PRO B 1 425 ? -6.270   -22.052 91.343  1.00 65.48  ? 485 PRO B CA  1 
ATOM   7565  C C   . PRO B 1 425 ? -7.290   -21.805 90.213  1.00 68.04  ? 485 PRO B C   1 
ATOM   7566  O O   . PRO B 1 425 ? -8.306   -21.149 90.448  1.00 78.40  ? 485 PRO B O   1 
ATOM   7567  C CB  . PRO B 1 425 ? -6.849   -23.062 92.353  1.00 61.73  ? 485 PRO B CB  1 
ATOM   7568  C CG  . PRO B 1 425 ? -7.341   -22.202 93.516  1.00 61.25  ? 485 PRO B CG  1 
ATOM   7569  C CD  . PRO B 1 425 ? -6.489   -20.945 93.505  1.00 60.83  ? 485 PRO B CD  1 
ATOM   7570  N N   . ILE B 1 426 ? -6.996   -22.312 89.014  1.00 68.67  ? 486 ILE B N   1 
ATOM   7571  C CA  . ILE B 1 426 ? -7.893   -22.219 87.826  1.00 64.33  ? 486 ILE B CA  1 
ATOM   7572  C C   . ILE B 1 426 ? -8.923   -23.353 87.918  1.00 61.21  ? 486 ILE B C   1 
ATOM   7573  O O   . ILE B 1 426 ? -8.546   -24.542 87.769  1.00 53.01  ? 486 ILE B O   1 
ATOM   7574  C CB  . ILE B 1 426 ? -7.073   -22.207 86.515  1.00 67.30  ? 486 ILE B CB  1 
ATOM   7575  C CG1 . ILE B 1 426 ? -6.399   -20.853 86.291  1.00 72.22  ? 486 ILE B CG1 1 
ATOM   7576  C CG2 . ILE B 1 426 ? -7.926   -22.520 85.309  1.00 71.56  ? 486 ILE B CG2 1 
ATOM   7577  C CD1 . ILE B 1 426 ? -4.986   -20.796 86.753  1.00 78.88  ? 486 ILE B CD1 1 
ATOM   7578  N N   . ILE B 1 427 ? -10.176  -22.977 88.185  1.00 66.83  ? 487 ILE B N   1 
ATOM   7579  C CA  . ILE B 1 427 ? -11.351  -23.897 88.222  1.00 70.85  ? 487 ILE B CA  1 
ATOM   7580  C C   . ILE B 1 427 ? -12.299  -23.513 87.079  1.00 62.04  ? 487 ILE B C   1 
ATOM   7581  O O   . ILE B 1 427 ? -12.765  -22.341 87.039  1.00 52.95  ? 487 ILE B O   1 
ATOM   7582  C CB  . ILE B 1 427 ? -12.078  -23.877 89.587  1.00 75.30  ? 487 ILE B CB  1 
ATOM   7583  C CG1 . ILE B 1 427 ? -11.118  -23.890 90.782  1.00 68.84  ? 487 ILE B CG1 1 
ATOM   7584  C CG2 . ILE B 1 427 ? -13.100  -25.020 89.660  1.00 82.14  ? 487 ILE B CG2 1 
ATOM   7585  C CD1 . ILE B 1 427 ? -10.259  -25.124 90.878  1.00 69.71  ? 487 ILE B CD1 1 
ATOM   7586  N N   . PHE B 1 428 ? -12.553  -24.497 86.216  1.00 54.26  ? 488 PHE B N   1 
ATOM   7587  C CA  . PHE B 1 428 ? -13.417  -24.443 85.018  1.00 56.69  ? 488 PHE B CA  1 
ATOM   7588  C C   . PHE B 1 428 ? -14.517  -25.495 85.183  1.00 59.16  ? 488 PHE B C   1 
ATOM   7589  O O   . PHE B 1 428 ? -14.245  -26.720 85.093  1.00 63.35  ? 488 PHE B O   1 
ATOM   7590  C CB  . PHE B 1 428 ? -12.577  -24.665 83.753  1.00 60.52  ? 488 PHE B CB  1 
ATOM   7591  C CG  . PHE B 1 428 ? -11.933  -23.427 83.166  1.00 62.22  ? 488 PHE B CG  1 
ATOM   7592  C CD1 . PHE B 1 428 ? -11.767  -22.264 83.909  1.00 63.97  ? 488 PHE B CD1 1 
ATOM   7593  C CD2 . PHE B 1 428 ? -11.492  -23.412 81.860  1.00 57.84  ? 488 PHE B CD2 1 
ATOM   7594  C CE1 . PHE B 1 428 ? -11.160  -21.138 83.371  1.00 63.40  ? 488 PHE B CE1 1 
ATOM   7595  C CE2 . PHE B 1 428 ? -10.907  -22.277 81.317  1.00 60.63  ? 488 PHE B CE2 1 
ATOM   7596  C CZ  . PHE B 1 428 ? -10.725  -21.145 82.069  1.00 59.77  ? 488 PHE B CZ  1 
ATOM   7597  N N   . SER B 1 429 ? -15.731  -25.013 85.449  1.00 60.22  ? 489 SER B N   1 
ATOM   7598  C CA  . SER B 1 429 ? -16.963  -25.817 85.648  1.00 58.65  ? 489 SER B CA  1 
ATOM   7599  C C   . SER B 1 429 ? -17.814  -25.743 84.375  1.00 63.48  ? 489 SER B C   1 
ATOM   7600  O O   . SER B 1 429 ? -18.627  -24.833 84.232  1.00 65.93  ? 489 SER B O   1 
ATOM   7601  C CB  . SER B 1 429 ? -17.686  -25.319 86.854  1.00 57.54  ? 489 SER B CB  1 
ATOM   7602  O OG  . SER B 1 429 ? -18.704  -26.226 87.212  1.00 78.19  ? 489 SER B OG  1 
ATOM   7603  N N   . LEU B 1 430 ? -17.594  -26.661 83.449  1.00 70.88  ? 490 LEU B N   1 
ATOM   7604  C CA  . LEU B 1 430 ? -18.048  -26.485 82.039  1.00 67.68  ? 490 LEU B CA  1 
ATOM   7605  C C   . LEU B 1 430 ? -19.465  -27.041 81.841  1.00 61.08  ? 490 LEU B C   1 
ATOM   7606  O O   . LEU B 1 430 ? -20.191  -26.473 81.033  1.00 61.42  ? 490 LEU B O   1 
ATOM   7607  C CB  . LEU B 1 430 ? -17.051  -27.164 81.093  1.00 68.12  ? 490 LEU B CB  1 
ATOM   7608  C CG  . LEU B 1 430 ? -15.761  -26.398 80.805  1.00 66.06  ? 490 LEU B CG  1 
ATOM   7609  C CD1 . LEU B 1 430 ? -15.114  -26.896 79.534  1.00 70.17  ? 490 LEU B CD1 1 
ATOM   7610  C CD2 . LEU B 1 430 ? -16.004  -24.905 80.704  1.00 73.86  ? 490 LEU B CD2 1 
ATOM   7611  N N   . SER B 1 431 ? -19.844  -28.104 82.549  1.00 58.35  ? 491 SER B N   1 
ATOM   7612  C CA  . SER B 1 431 ? -21.134  -28.809 82.323  1.00 58.33  ? 491 SER B CA  1 
ATOM   7613  C C   . SER B 1 431 ? -22.316  -27.827 82.369  1.00 59.90  ? 491 SER B C   1 
ATOM   7614  O O   . SER B 1 431 ? -22.218  -26.792 83.074  1.00 57.72  ? 491 SER B O   1 
ATOM   7615  C CB  . SER B 1 431 ? -21.318  -29.957 83.283  1.00 57.37  ? 491 SER B CB  1 
ATOM   7616  O OG  . SER B 1 431 ? -20.368  -30.981 83.017  1.00 54.54  ? 491 SER B OG  1 
ATOM   7617  N N   . ASN B 1 432 ? -23.377  -28.148 81.616  1.00 65.84  ? 492 ASN B N   1 
ATOM   7618  C CA  . ASN B 1 432 ? -24.652  -27.380 81.483  1.00 60.88  ? 492 ASN B CA  1 
ATOM   7619  C C   . ASN B 1 432 ? -25.838  -28.340 81.593  1.00 61.72  ? 492 ASN B C   1 
ATOM   7620  O O   . ASN B 1 432 ? -25.725  -29.548 81.316  1.00 53.01  ? 492 ASN B O   1 
ATOM   7621  C CB  . ASN B 1 432 ? -24.734  -26.630 80.146  1.00 64.95  ? 492 ASN B CB  1 
ATOM   7622  C CG  . ASN B 1 432 ? -23.620  -25.622 79.969  1.00 64.23  ? 492 ASN B CG  1 
ATOM   7623  O OD1 . ASN B 1 432 ? -23.400  -24.803 80.855  1.00 64.43  ? 492 ASN B OD1 1 
ATOM   7624  N ND2 . ASN B 1 432 ? -22.905  -25.688 78.853  1.00 54.05  ? 492 ASN B ND2 1 
ATOM   7625  N N   . PRO B 1 433 ? -27.031  -27.845 81.987  1.00 58.32  ? 493 PRO B N   1 
ATOM   7626  C CA  . PRO B 1 433 ? -27.234  -26.446 82.359  1.00 57.94  ? 493 PRO B CA  1 
ATOM   7627  C C   . PRO B 1 433 ? -26.777  -26.201 83.810  1.00 66.18  ? 493 PRO B C   1 
ATOM   7628  O O   . PRO B 1 433 ? -26.071  -27.042 84.341  1.00 63.92  ? 493 PRO B O   1 
ATOM   7629  C CB  . PRO B 1 433 ? -28.758  -26.275 82.177  1.00 55.03  ? 493 PRO B CB  1 
ATOM   7630  C CG  . PRO B 1 433 ? -29.318  -27.648 82.526  1.00 49.49  ? 493 PRO B CG  1 
ATOM   7631  C CD  . PRO B 1 433 ? -28.254  -28.644 82.122  1.00 50.98  ? 493 PRO B CD  1 
ATOM   7632  N N   . THR B 1 434 ? -27.210  -25.087 84.427  1.00 61.80  ? 494 THR B N   1 
ATOM   7633  C CA  . THR B 1 434 ? -26.780  -24.602 85.767  1.00 53.28  ? 494 THR B CA  1 
ATOM   7634  C C   . THR B 1 434 ? -26.875  -25.737 86.783  1.00 53.57  ? 494 THR B C   1 
ATOM   7635  O O   . THR B 1 434 ? -25.918  -25.937 87.528  1.00 57.95  ? 494 THR B O   1 
ATOM   7636  C CB  . THR B 1 434 ? -27.587  -23.363 86.180  1.00 57.09  ? 494 THR B CB  1 
ATOM   7637  O OG1 . THR B 1 434 ? -27.580  -22.405 85.111  1.00 54.47  ? 494 THR B OG1 1 
ATOM   7638  C CG2 . THR B 1 434 ? -27.054  -22.696 87.426  1.00 54.71  ? 494 THR B CG2 1 
ATOM   7639  N N   . SER B 1 435 ? -27.982  -26.477 86.783  1.00 58.46  ? 495 SER B N   1 
ATOM   7640  C CA  . SER B 1 435 ? -28.245  -27.634 87.681  1.00 63.88  ? 495 SER B CA  1 
ATOM   7641  C C   . SER B 1 435 ? -27.170  -28.729 87.557  1.00 66.39  ? 495 SER B C   1 
ATOM   7642  O O   . SER B 1 435 ? -27.050  -29.534 88.501  1.00 66.56  ? 495 SER B O   1 
ATOM   7643  C CB  . SER B 1 435 ? -29.579  -28.225 87.382  1.00 68.03  ? 495 SER B CB  1 
ATOM   7644  O OG  . SER B 1 435 ? -29.516  -28.929 86.143  1.00 77.01  ? 495 SER B OG  1 
ATOM   7645  N N   . HIS B 1 436 ? -26.439  -28.810 86.442  1.00 59.84  ? 496 HIS B N   1 
ATOM   7646  C CA  . HIS B 1 436 ? -25.365  -29.824 86.270  1.00 61.97  ? 496 HIS B CA  1 
ATOM   7647  C C   . HIS B 1 436 ? -23.946  -29.225 86.387  1.00 66.21  ? 496 HIS B C   1 
ATOM   7648  O O   . HIS B 1 436 ? -22.968  -30.025 86.280  1.00 66.78  ? 496 HIS B O   1 
ATOM   7649  C CB  . HIS B 1 436 ? -25.606  -30.591 84.975  1.00 60.30  ? 496 HIS B CB  1 
ATOM   7650  C CG  . HIS B 1 436 ? -26.654  -31.623 85.161  1.00 59.50  ? 496 HIS B CG  1 
ATOM   7651  N ND1 . HIS B 1 436 ? -27.830  -31.590 84.488  1.00 66.82  ? 496 HIS B ND1 1 
ATOM   7652  C CD2 . HIS B 1 436 ? -26.705  -32.691 85.977  1.00 60.05  ? 496 HIS B CD2 1 
ATOM   7653  C CE1 . HIS B 1 436 ? -28.552  -32.631 84.822  1.00 65.49  ? 496 HIS B CE1 1 
ATOM   7654  N NE2 . HIS B 1 436 ? -27.890  -33.303 85.746  1.00 71.68  ? 496 HIS B NE2 1 
ATOM   7655  N N   . SER B 1 437 ? -23.820  -27.907 86.618  1.00 56.10  ? 497 SER B N   1 
ATOM   7656  C CA  . SER B 1 437 ? -22.535  -27.215 86.905  1.00 49.65  ? 497 SER B CA  1 
ATOM   7657  C C   . SER B 1 437 ? -21.811  -27.972 88.026  1.00 52.19  ? 497 SER B C   1 
ATOM   7658  O O   . SER B 1 437 ? -22.451  -28.248 89.053  1.00 50.71  ? 497 SER B O   1 
ATOM   7659  C CB  . SER B 1 437 ? -22.770  -25.759 87.265  1.00 51.12  ? 497 SER B CB  1 
ATOM   7660  O OG  . SER B 1 437 ? -21.713  -24.932 86.795  1.00 47.76  ? 497 SER B OG  1 
ATOM   7661  N N   . GLU B 1 438 ? -20.529  -28.299 87.835  1.00 61.31  ? 498 GLU B N   1 
ATOM   7662  C CA  . GLU B 1 438 ? -19.671  -29.048 88.814  1.00 59.54  ? 498 GLU B CA  1 
ATOM   7663  C C   . GLU B 1 438 ? -19.513  -28.255 90.126  1.00 55.39  ? 498 GLU B C   1 
ATOM   7664  O O   . GLU B 1 438 ? -19.345  -28.869 91.206  1.00 52.12  ? 498 GLU B O   1 
ATOM   7665  C CB  . GLU B 1 438 ? -18.319  -29.373 88.179  1.00 58.65  ? 498 GLU B CB  1 
ATOM   7666  C CG  . GLU B 1 438 ? -18.406  -30.447 87.101  1.00 62.57  ? 498 GLU B CG  1 
ATOM   7667  C CD  . GLU B 1 438 ? -18.662  -30.019 85.658  1.00 64.22  ? 498 GLU B CD  1 
ATOM   7668  O OE1 . GLU B 1 438 ? -18.769  -28.776 85.362  1.00 50.35  ? 498 GLU B OE1 1 
ATOM   7669  O OE2 . GLU B 1 438 ? -18.726  -30.952 84.816  1.00 63.63  ? 498 GLU B OE2 1 
ATOM   7670  N N   . CYS B 1 439 ? -19.566  -26.928 90.050  1.00 54.03  ? 499 CYS B N   1 
ATOM   7671  C CA  . CYS B 1 439 ? -19.800  -26.056 91.220  1.00 55.49  ? 499 CYS B CA  1 
ATOM   7672  C C   . CYS B 1 439 ? -20.458  -24.772 90.729  1.00 59.38  ? 499 CYS B C   1 
ATOM   7673  O O   . CYS B 1 439 ? -20.509  -24.584 89.521  1.00 59.32  ? 499 CYS B O   1 
ATOM   7674  C CB  . CYS B 1 439 ? -18.524  -25.802 92.001  1.00 53.35  ? 499 CYS B CB  1 
ATOM   7675  S SG  . CYS B 1 439 ? -17.234  -24.928 91.079  1.00 63.42  ? 499 CYS B SG  1 
ATOM   7676  N N   . THR B 1 440 ? -20.992  -23.980 91.657  1.00 64.35  ? 500 THR B N   1 
ATOM   7677  C CA  . THR B 1 440 ? -21.525  -22.618 91.423  1.00 59.92  ? 500 THR B CA  1 
ATOM   7678  C C   . THR B 1 440 ? -20.353  -21.649 91.441  1.00 59.05  ? 500 THR B C   1 
ATOM   7679  O O   . THR B 1 440 ? -19.268  -22.041 91.936  1.00 52.25  ? 500 THR B O   1 
ATOM   7680  C CB  . THR B 1 440 ? -22.564  -22.213 92.483  1.00 71.55  ? 500 THR B CB  1 
ATOM   7681  O OG1 . THR B 1 440 ? -21.924  -21.790 93.686  1.00 75.43  ? 500 THR B OG1 1 
ATOM   7682  C CG2 . THR B 1 440 ? -23.538  -23.322 92.827  1.00 75.12  ? 500 THR B CG2 1 
ATOM   7683  N N   . ALA B 1 441 ? -20.573  -20.416 90.977  1.00 65.16  ? 501 ALA B N   1 
ATOM   7684  C CA  . ALA B 1 441 ? -19.629  -19.283 91.148  1.00 56.78  ? 501 ALA B CA  1 
ATOM   7685  C C   . ALA B 1 441 ? -19.499  -18.939 92.638  1.00 53.86  ? 501 ALA B C   1 
ATOM   7686  O O   . ALA B 1 441 ? -18.367  -18.666 93.061  1.00 48.47  ? 501 ALA B O   1 
ATOM   7687  C CB  . ALA B 1 441 ? -20.076  -18.085 90.371  1.00 57.64  ? 501 ALA B CB  1 
ATOM   7688  N N   . GLU B 1 442 ? -20.606  -18.952 93.396  1.00 54.44  ? 502 GLU B N   1 
ATOM   7689  C CA  . GLU B 1 442 ? -20.559  -18.647 94.843  1.00 53.65  ? 502 GLU B CA  1 
ATOM   7690  C C   . GLU B 1 442 ? -19.690  -19.670 95.574  1.00 51.19  ? 502 GLU B C   1 
ATOM   7691  O O   . GLU B 1 442 ? -18.930  -19.225 96.411  1.00 57.98  ? 502 GLU B O   1 
ATOM   7692  C CB  . GLU B 1 442 ? -21.924  -18.560 95.502  1.00 60.09  ? 502 GLU B CB  1 
ATOM   7693  C CG  . GLU B 1 442 ? -21.791  -17.966 96.887  1.00 70.81  ? 502 GLU B CG  1 
ATOM   7694  C CD  . GLU B 1 442 ? -22.782  -16.853 97.115  1.00 87.37  ? 502 GLU B CD  1 
ATOM   7695  O OE1 . GLU B 1 442 ? -22.380  -15.649 97.105  1.00 87.90  ? 502 GLU B OE1 1 
ATOM   7696  O OE2 . GLU B 1 442 ? -23.960  -17.204 97.263  1.00 97.06  ? 502 GLU B OE2 1 
ATOM   7697  N N   . GLN B 1 443 ? -19.787  -20.969 95.289  1.00 54.23  ? 503 GLN B N   1 
ATOM   7698  C CA  . GLN B 1 443 ? -19.039  -22.039 96.014  1.00 61.54  ? 503 GLN B CA  1 
ATOM   7699  C C   . GLN B 1 443 ? -17.531  -21.866 95.787  1.00 65.39  ? 503 GLN B C   1 
ATOM   7700  O O   . GLN B 1 443 ? -16.771  -21.904 96.787  1.00 67.98  ? 503 GLN B O   1 
ATOM   7701  C CB  . GLN B 1 443 ? -19.501  -23.419 95.545  1.00 65.57  ? 503 GLN B CB  1 
ATOM   7702  C CG  . GLN B 1 443 ? -20.930  -23.755 95.942  1.00 63.04  ? 503 GLN B CG  1 
ATOM   7703  C CD  . GLN B 1 443 ? -21.414  -25.021 95.280  1.00 68.16  ? 503 GLN B CD  1 
ATOM   7704  O OE1 . GLN B 1 443 ? -20.843  -25.497 94.305  1.00 69.77  ? 503 GLN B OE1 1 
ATOM   7705  N NE2 . GLN B 1 443 ? -22.485  -25.581 95.815  1.00 80.39  ? 503 GLN B NE2 1 
ATOM   7706  N N   . ALA B 1 444 ? -17.129  -21.655 94.525  1.00 70.90  ? 504 ALA B N   1 
ATOM   7707  C CA  . ALA B 1 444 ? -15.726  -21.561 94.044  1.00 65.68  ? 504 ALA B CA  1 
ATOM   7708  C C   . ALA B 1 444 ? -15.014  -20.376 94.692  1.00 63.45  ? 504 ALA B C   1 
ATOM   7709  O O   . ALA B 1 444 ? -13.878  -20.564 95.081  1.00 70.55  ? 504 ALA B O   1 
ATOM   7710  C CB  . ALA B 1 444 ? -15.704  -21.430 92.540  1.00 66.80  ? 504 ALA B CB  1 
ATOM   7711  N N   . TYR B 1 445 ? -15.638  -19.198 94.752  1.00 64.52  ? 505 TYR B N   1 
ATOM   7712  C CA  . TYR B 1 445 ? -15.081  -17.971 95.398  1.00 72.91  ? 505 TYR B CA  1 
ATOM   7713  C C   . TYR B 1 445 ? -15.115  -18.067 96.940  1.00 72.60  ? 505 TYR B C   1 
ATOM   7714  O O   . TYR B 1 445 ? -14.175  -17.558 97.593  1.00 89.53  ? 505 TYR B O   1 
ATOM   7715  C CB  . TYR B 1 445 ? -15.756  -16.689 94.888  1.00 76.76  ? 505 TYR B CB  1 
ATOM   7716  C CG  . TYR B 1 445 ? -15.446  -16.359 93.448  1.00 78.76  ? 505 TYR B CG  1 
ATOM   7717  C CD1 . TYR B 1 445 ? -16.168  -16.929 92.429  1.00 82.31  ? 505 TYR B CD1 1 
ATOM   7718  C CD2 . TYR B 1 445 ? -14.417  -15.495 93.096  1.00 79.87  ? 505 TYR B CD2 1 
ATOM   7719  C CE1 . TYR B 1 445 ? -15.887  -16.655 91.101  1.00 91.08  ? 505 TYR B CE1 1 
ATOM   7720  C CE2 . TYR B 1 445 ? -14.114  -15.215 91.775  1.00 85.31  ? 505 TYR B CE2 1 
ATOM   7721  C CZ  . TYR B 1 445 ? -14.858  -15.798 90.763  1.00 88.64  ? 505 TYR B CZ  1 
ATOM   7722  O OH  . TYR B 1 445 ? -14.629  -15.560 89.430  1.00 76.86  ? 505 TYR B OH  1 
ATOM   7723  N N   . THR B 1 446 ? -16.134  -18.686 97.541  1.00 62.04  ? 506 THR B N   1 
ATOM   7724  C CA  . THR B 1 446 ? -16.215  -18.879 99.018  1.00 62.04  ? 506 THR B CA  1 
ATOM   7725  C C   . THR B 1 446 ? -15.171  -19.918 99.467  1.00 67.59  ? 506 THR B C   1 
ATOM   7726  O O   . THR B 1 446 ? -14.335  -19.560 100.306 1.00 67.38  ? 506 THR B O   1 
ATOM   7727  C CB  . THR B 1 446 ? -17.627  -19.280 99.441  1.00 58.61  ? 506 THR B CB  1 
ATOM   7728  O OG1 . THR B 1 446 ? -18.477  -18.396 98.726  1.00 68.77  ? 506 THR B OG1 1 
ATOM   7729  C CG2 . THR B 1 446 ? -17.912  -19.143 100.915 1.00 65.49  ? 506 THR B CG2 1 
ATOM   7730  N N   . TRP B 1 447 ? -15.185  -21.130 98.899  1.00 62.86  ? 507 TRP B N   1 
ATOM   7731  C CA  . TRP B 1 447 ? -14.353  -22.281 99.340  1.00 64.55  ? 507 TRP B CA  1 
ATOM   7732  C C   . TRP B 1 447 ? -12.872  -22.087 98.980  1.00 59.21  ? 507 TRP B C   1 
ATOM   7733  O O   . TRP B 1 447 ? -12.032  -22.929 99.384  1.00 56.78  ? 507 TRP B O   1 
ATOM   7734  C CB  . TRP B 1 447 ? -14.914  -23.570 98.727  1.00 78.29  ? 507 TRP B CB  1 
ATOM   7735  C CG  . TRP B 1 447 ? -16.314  -23.894 99.144  1.00 76.88  ? 507 TRP B CG  1 
ATOM   7736  C CD1 . TRP B 1 447 ? -16.971  -23.412 100.236 1.00 77.43  ? 507 TRP B CD1 1 
ATOM   7737  C CD2 . TRP B 1 447 ? -17.219  -24.802 98.491  1.00 78.86  ? 507 TRP B CD2 1 
ATOM   7738  N NE1 . TRP B 1 447 ? -18.216  -23.970 100.322 1.00 81.83  ? 507 TRP B NE1 1 
ATOM   7739  C CE2 . TRP B 1 447 ? -18.402  -24.822 99.262  1.00 79.34  ? 507 TRP B CE2 1 
ATOM   7740  C CE3 . TRP B 1 447 ? -17.155  -25.595 97.335  1.00 76.14  ? 507 TRP B CE3 1 
ATOM   7741  C CZ2 . TRP B 1 447 ? -19.501  -25.611 98.914  1.00 73.07  ? 507 TRP B CZ2 1 
ATOM   7742  C CZ3 . TRP B 1 447 ? -18.251  -26.351 96.979  1.00 71.43  ? 507 TRP B CZ3 1 
ATOM   7743  C CH2 . TRP B 1 447 ? -19.406  -26.364 97.761  1.00 76.12  ? 507 TRP B CH2 1 
ATOM   7744  N N   . SER B 1 448 ? -12.549  -21.033 98.235  1.00 59.85  ? 508 SER B N   1 
ATOM   7745  C CA  . SER B 1 448 ? -11.166  -20.668 97.839  1.00 60.98  ? 508 SER B CA  1 
ATOM   7746  C C   . SER B 1 448 ? -10.746  -19.324 98.426  1.00 53.38  ? 508 SER B C   1 
ATOM   7747  O O   . SER B 1 448 ? -9.767   -18.817 97.944  1.00 51.58  ? 508 SER B O   1 
ATOM   7748  C CB  . SER B 1 448 ? -11.030  -20.599 96.345  1.00 70.52  ? 508 SER B CB  1 
ATOM   7749  O OG  . SER B 1 448 ? -11.442  -19.328 95.889  1.00 72.30  ? 508 SER B OG  1 
ATOM   7750  N N   . GLN B 1 449 ? -11.513  -18.758 99.352  1.00 65.56  ? 509 GLN B N   1 
ATOM   7751  C CA  . GLN B 1 449 ? -11.263  -17.427 100.006 1.00 76.75  ? 509 GLN B CA  1 
ATOM   7752  C C   . GLN B 1 449 ? -10.999  -16.321 98.954  1.00 67.41  ? 509 GLN B C   1 
ATOM   7753  O O   . GLN B 1 449 ? -10.133  -15.455 99.161  1.00 59.14  ? 509 GLN B O   1 
ATOM   7754  C CB  . GLN B 1 449 ? -10.131  -17.566 101.028 1.00 82.83  ? 509 GLN B CB  1 
ATOM   7755  C CG  . GLN B 1 449 ? -10.476  -18.501 102.182 1.00 84.97  ? 509 GLN B CG  1 
ATOM   7756  C CD  . GLN B 1 449 ? -9.257   -19.014 102.915 1.00 94.59  ? 509 GLN B CD  1 
ATOM   7757  O OE1 . GLN B 1 449 ? -8.105   -18.731 102.574 1.00 116.96 ? 509 GLN B OE1 1 
ATOM   7758  N NE2 . GLN B 1 449 ? -9.507   -19.799 103.944 1.00 99.05  ? 509 GLN B NE2 1 
ATOM   7759  N N   . GLY B 1 450 ? -11.771  -16.324 97.874  1.00 67.72  ? 510 GLY B N   1 
ATOM   7760  C CA  . GLY B 1 450 ? -11.757  -15.269 96.849  1.00 67.88  ? 510 GLY B CA  1 
ATOM   7761  C C   . GLY B 1 450 ? -10.560  -15.341 95.916  1.00 62.50  ? 510 GLY B C   1 
ATOM   7762  O O   . GLY B 1 450 ? -10.291  -14.340 95.208  1.00 61.51  ? 510 GLY B O   1 
ATOM   7763  N N   . ARG B 1 451 ? -9.878   -16.480 95.872  1.00 62.15  ? 511 ARG B N   1 
ATOM   7764  C CA  . ARG B 1 451 ? -8.528   -16.592 95.251  1.00 72.52  ? 511 ARG B CA  1 
ATOM   7765  C C   . ARG B 1 451 ? -8.589   -17.385 93.933  1.00 67.06  ? 511 ARG B C   1 
ATOM   7766  O O   . ARG B 1 451 ? -7.608   -17.344 93.192  1.00 76.97  ? 511 ARG B O   1 
ATOM   7767  C CB  . ARG B 1 451 ? -7.545   -17.231 96.250  1.00 71.80  ? 511 ARG B CB  1 
ATOM   7768  C CG  . ARG B 1 451 ? -7.078   -16.335 97.397  1.00 63.05  ? 511 ARG B CG  1 
ATOM   7769  C CD  . ARG B 1 451 ? -5.892   -16.946 98.156  1.00 63.87  ? 511 ARG B CD  1 
ATOM   7770  N NE  . ARG B 1 451 ? -6.175   -18.121 98.995  1.00 70.42  ? 511 ARG B NE  1 
ATOM   7771  C CZ  . ARG B 1 451 ? -5.994   -19.414 98.662  1.00 64.13  ? 511 ARG B CZ  1 
ATOM   7772  N NH1 . ARG B 1 451 ? -5.518   -19.779 97.491  1.00 59.55  ? 511 ARG B NH1 1 
ATOM   7773  N NH2 . ARG B 1 451 ? -6.290   -20.370 99.522  1.00 70.16  ? 511 ARG B NH2 1 
ATOM   7774  N N   . SER B 1 452 ? -9.681   -18.086 93.642  1.00 76.15  ? 512 SER B N   1 
ATOM   7775  C CA  . SER B 1 452 ? -9.830   -18.897 92.402  1.00 80.23  ? 512 SER B CA  1 
ATOM   7776  C C   . SER B 1 452 ? -10.071  -17.977 91.193  1.00 75.33  ? 512 SER B C   1 
ATOM   7777  O O   . SER B 1 452 ? -10.698  -16.903 91.348  1.00 65.43  ? 512 SER B O   1 
ATOM   7778  C CB  . SER B 1 452 ? -10.914  -19.922 92.526  1.00 80.55  ? 512 SER B CB  1 
ATOM   7779  O OG  . SER B 1 452 ? -12.163  -19.271 92.640  1.00 88.00  ? 512 SER B OG  1 
ATOM   7780  N N   . ILE B 1 453 ? -9.507   -18.378 90.057  1.00 73.63  ? 513 ILE B N   1 
ATOM   7781  C CA  . ILE B 1 453 ? -9.870   -17.923 88.692  1.00 70.24  ? 513 ILE B CA  1 
ATOM   7782  C C   . ILE B 1 453 ? -10.910  -18.924 88.169  1.00 72.61  ? 513 ILE B C   1 
ATOM   7783  O O   . ILE B 1 453 ? -10.564  -20.090 87.849  1.00 71.98  ? 513 ILE B O   1 
ATOM   7784  C CB  . ILE B 1 453 ? -8.616   -17.850 87.801  1.00 75.25  ? 513 ILE B CB  1 
ATOM   7785  C CG1 . ILE B 1 453 ? -7.547   -16.911 88.377  1.00 76.45  ? 513 ILE B CG1 1 
ATOM   7786  C CG2 . ILE B 1 453 ? -9.002   -17.491 86.377  1.00 69.51  ? 513 ILE B CG2 1 
ATOM   7787  C CD1 . ILE B 1 453 ? -8.034   -15.515 88.795  1.00 72.09  ? 513 ILE B CD1 1 
ATOM   7788  N N   . PHE B 1 454 ? -12.165  -18.492 88.149  1.00 73.60  ? 514 PHE B N   1 
ATOM   7789  C CA  . PHE B 1 454 ? -13.355  -19.332 87.894  1.00 60.16  ? 514 PHE B CA  1 
ATOM   7790  C C   . PHE B 1 454 ? -14.014  -18.923 86.579  1.00 58.53  ? 514 PHE B C   1 
ATOM   7791  O O   . PHE B 1 454 ? -14.183  -17.717 86.289  1.00 59.80  ? 514 PHE B O   1 
ATOM   7792  C CB  . PHE B 1 454 ? -14.393  -19.195 89.013  1.00 56.93  ? 514 PHE B CB  1 
ATOM   7793  C CG  . PHE B 1 454 ? -15.554  -20.134 88.824  1.00 57.61  ? 514 PHE B CG  1 
ATOM   7794  C CD1 . PHE B 1 454 ? -15.363  -21.518 88.851  1.00 55.15  ? 514 PHE B CD1 1 
ATOM   7795  C CD2 . PHE B 1 454 ? -16.815  -19.639 88.534  1.00 52.05  ? 514 PHE B CD2 1 
ATOM   7796  C CE1 . PHE B 1 454 ? -16.420  -22.383 88.644  1.00 49.63  ? 514 PHE B CE1 1 
ATOM   7797  C CE2 . PHE B 1 454 ? -17.874  -20.506 88.326  1.00 53.25  ? 514 PHE B CE2 1 
ATOM   7798  C CZ  . PHE B 1 454 ? -17.669  -21.877 88.382  1.00 55.48  ? 514 PHE B CZ  1 
ATOM   7799  N N   . ALA B 1 455 ? -14.438  -19.931 85.828  1.00 55.94  ? 515 ALA B N   1 
ATOM   7800  C CA  . ALA B 1 455 ? -15.363  -19.788 84.692  1.00 51.88  ? 515 ALA B CA  1 
ATOM   7801  C C   . ALA B 1 455 ? -16.168  -21.087 84.553  1.00 57.74  ? 515 ALA B C   1 
ATOM   7802  O O   . ALA B 1 455 ? -15.675  -22.150 85.024  1.00 57.79  ? 515 ALA B O   1 
ATOM   7803  C CB  . ALA B 1 455 ? -14.551  -19.470 83.486  1.00 57.68  ? 515 ALA B CB  1 
ATOM   7804  N N   . SER B 1 456 ? -17.364  -20.994 83.949  1.00 56.23  ? 516 SER B N   1 
ATOM   7805  C CA  . SER B 1 456 ? -18.371  -22.083 83.865  1.00 53.16  ? 516 SER B CA  1 
ATOM   7806  C C   . SER B 1 456 ? -19.119  -22.015 82.543  1.00 52.39  ? 516 SER B C   1 
ATOM   7807  O O   . SER B 1 456 ? -19.092  -20.928 81.929  1.00 48.05  ? 516 SER B O   1 
ATOM   7808  C CB  . SER B 1 456 ? -19.348  -22.021 85.018  1.00 57.37  ? 516 SER B CB  1 
ATOM   7809  O OG  . SER B 1 456 ? -20.147  -20.855 84.963  1.00 68.89  ? 516 SER B OG  1 
ATOM   7810  N N   . GLY B 1 457 ? -19.800  -23.116 82.179  1.00 52.47  ? 517 GLY B N   1 
ATOM   7811  C CA  . GLY B 1 457 ? -20.609  -23.229 80.948  1.00 57.68  ? 517 GLY B CA  1 
ATOM   7812  C C   . GLY B 1 457 ? -21.871  -22.378 80.974  1.00 60.83  ? 517 GLY B C   1 
ATOM   7813  O O   . GLY B 1 457 ? -22.231  -21.773 79.928  1.00 59.73  ? 517 GLY B O   1 
ATOM   7814  N N   . SER B 1 458 ? -22.569  -22.368 82.106  1.00 63.66  ? 518 SER B N   1 
ATOM   7815  C CA  . SER B 1 458 ? -23.877  -21.694 82.260  1.00 62.09  ? 518 SER B CA  1 
ATOM   7816  C C   . SER B 1 458 ? -23.691  -20.398 83.038  1.00 60.05  ? 518 SER B C   1 
ATOM   7817  O O   . SER B 1 458 ? -22.835  -20.344 83.906  1.00 59.40  ? 518 SER B O   1 
ATOM   7818  C CB  . SER B 1 458 ? -24.797  -22.653 82.919  1.00 63.25  ? 518 SER B CB  1 
ATOM   7819  O OG  . SER B 1 458 ? -24.945  -23.793 82.087  1.00 58.58  ? 518 SER B OG  1 
ATOM   7820  N N   . PRO B 1 459 ? -24.463  -19.318 82.775  1.00 59.62  ? 519 PRO B N   1 
ATOM   7821  C CA  . PRO B 1 459 ? -24.199  -18.018 83.397  1.00 60.96  ? 519 PRO B CA  1 
ATOM   7822  C C   . PRO B 1 459 ? -24.518  -18.065 84.901  1.00 60.98  ? 519 PRO B C   1 
ATOM   7823  O O   . PRO B 1 459 ? -25.424  -18.793 85.255  1.00 71.77  ? 519 PRO B O   1 
ATOM   7824  C CB  . PRO B 1 459 ? -25.148  -17.055 82.678  1.00 59.79  ? 519 PRO B CB  1 
ATOM   7825  C CG  . PRO B 1 459 ? -26.281  -17.951 82.282  1.00 66.75  ? 519 PRO B CG  1 
ATOM   7826  C CD  . PRO B 1 459 ? -25.662  -19.295 81.931  1.00 62.31  ? 519 PRO B CD  1 
ATOM   7827  N N   . PHE B 1 460 ? -23.739  -17.341 85.719  1.00 56.54  ? 520 PHE B N   1 
ATOM   7828  C CA  . PHE B 1 460 ? -23.930  -17.096 87.178  1.00 52.98  ? 520 PHE B CA  1 
ATOM   7829  C C   . PHE B 1 460 ? -23.839  -15.587 87.444  1.00 56.61  ? 520 PHE B C   1 
ATOM   7830  O O   . PHE B 1 460 ? -23.002  -14.882 86.860  1.00 53.26  ? 520 PHE B O   1 
ATOM   7831  C CB  . PHE B 1 460 ? -22.851  -17.792 88.000  1.00 46.73  ? 520 PHE B CB  1 
ATOM   7832  C CG  . PHE B 1 460 ? -23.022  -19.280 88.121  1.00 48.58  ? 520 PHE B CG  1 
ATOM   7833  C CD1 . PHE B 1 460 ? -23.947  -19.806 88.997  1.00 52.39  ? 520 PHE B CD1 1 
ATOM   7834  C CD2 . PHE B 1 460 ? -22.261  -20.172 87.374  1.00 53.40  ? 520 PHE B CD2 1 
ATOM   7835  C CE1 . PHE B 1 460 ? -24.119  -21.182 89.112  1.00 52.37  ? 520 PHE B CE1 1 
ATOM   7836  C CE2 . PHE B 1 460 ? -22.430  -21.548 87.502  1.00 50.80  ? 520 PHE B CE2 1 
ATOM   7837  C CZ  . PHE B 1 460 ? -23.358  -22.053 88.375  1.00 48.85  ? 520 PHE B CZ  1 
ATOM   7838  N N   . ALA B 1 461 ? -24.683  -15.062 88.314  1.00 61.29  ? 521 ALA B N   1 
ATOM   7839  C CA  . ALA B 1 461 ? -24.650  -13.622 88.626  1.00 61.63  ? 521 ALA B CA  1 
ATOM   7840  C C   . ALA B 1 461 ? -23.325  -13.321 89.321  1.00 61.84  ? 521 ALA B C   1 
ATOM   7841  O O   . ALA B 1 461 ? -22.671  -14.232 89.854  1.00 55.39  ? 521 ALA B O   1 
ATOM   7842  C CB  . ALA B 1 461 ? -25.835  -13.265 89.480  1.00 69.39  ? 521 ALA B CB  1 
ATOM   7843  N N   . PRO B 1 462 ? -22.904  -12.035 89.325  1.00 63.58  ? 522 PRO B N   1 
ATOM   7844  C CA  . PRO B 1 462 ? -21.752  -11.596 90.106  1.00 63.67  ? 522 PRO B CA  1 
ATOM   7845  C C   . PRO B 1 462 ? -21.845  -12.123 91.546  1.00 74.12  ? 522 PRO B C   1 
ATOM   7846  O O   . PRO B 1 462 ? -22.947  -12.206 92.063  1.00 83.81  ? 522 PRO B O   1 
ATOM   7847  C CB  . PRO B 1 462 ? -21.844  -10.060 90.049  1.00 60.69  ? 522 PRO B CB  1 
ATOM   7848  C CG  . PRO B 1 462 ? -22.547  -9.770  88.757  1.00 58.14  ? 522 PRO B CG  1 
ATOM   7849  C CD  . PRO B 1 462 ? -23.515  -10.923 88.571  1.00 64.01  ? 522 PRO B CD  1 
ATOM   7850  N N   . VAL B 1 463 ? -20.694  -12.463 92.142  1.00 75.18  ? 523 VAL B N   1 
ATOM   7851  C CA  . VAL B 1 463 ? -20.530  -13.044 93.514  1.00 72.12  ? 523 VAL B CA  1 
ATOM   7852  C C   . VAL B 1 463 ? -19.814  -11.983 94.371  1.00 70.70  ? 523 VAL B C   1 
ATOM   7853  O O   . VAL B 1 463 ? -18.821  -11.418 93.897  1.00 74.93  ? 523 VAL B O   1 
ATOM   7854  C CB  . VAL B 1 463 ? -19.775  -14.398 93.464  1.00 62.20  ? 523 VAL B CB  1 
ATOM   7855  C CG1 . VAL B 1 463 ? -19.438  -14.925 94.843  1.00 63.27  ? 523 VAL B CG1 1 
ATOM   7856  C CG2 . VAL B 1 463 ? -20.527  -15.474 92.695  1.00 58.30  ? 523 VAL B CG2 1 
ATOM   7857  N N   . GLU B 1 464 ? -20.325  -11.673 95.570  1.00 80.01  ? 524 GLU B N   1 
ATOM   7858  C CA  . GLU B 1 464 ? -19.719  -10.673 96.500  1.00 94.79  ? 524 GLU B CA  1 
ATOM   7859  C C   . GLU B 1 464 ? -18.966  -11.395 97.632  1.00 89.07  ? 524 GLU B C   1 
ATOM   7860  O O   . GLU B 1 464 ? -19.464  -12.413 98.128  1.00 72.01  ? 524 GLU B O   1 
ATOM   7861  C CB  . GLU B 1 464 ? -20.791  -9.710  97.021  1.00 99.13  ? 524 GLU B CB  1 
ATOM   7862  C CG  . GLU B 1 464 ? -21.169  -8.624  96.020  1.00 110.43 ? 524 GLU B CG  1 
ATOM   7863  C CD  . GLU B 1 464 ? -22.623  -8.595  95.550  1.00 108.01 ? 524 GLU B CD  1 
ATOM   7864  O OE1 . GLU B 1 464 ? -23.534  -8.897  96.374  1.00 81.29  ? 524 GLU B OE1 1 
ATOM   7865  O OE2 . GLU B 1 464 ? -22.836  -8.271  94.352  1.00 97.07  ? 524 GLU B OE2 1 
ATOM   7866  N N   . TYR B 1 465 ? -17.775  -10.892 97.979  1.00 100.12 ? 525 TYR B N   1 
ATOM   7867  C CA  . TYR B 1 465 ? -16.854  -11.425 99.025  1.00 97.38  ? 525 TYR B CA  1 
ATOM   7868  C C   . TYR B 1 465 ? -16.054  -10.271 99.652  1.00 98.47  ? 525 TYR B C   1 
ATOM   7869  O O   . TYR B 1 465 ? -15.186  -9.720  98.976  1.00 98.06  ? 525 TYR B O   1 
ATOM   7870  C CB  . TYR B 1 465 ? -15.964  -12.492 98.387  1.00 94.42  ? 525 TYR B CB  1 
ATOM   7871  C CG  . TYR B 1 465 ? -15.314  -13.432 99.357  1.00 86.78  ? 525 TYR B CG  1 
ATOM   7872  C CD1 . TYR B 1 465 ? -16.045  -14.448 99.948  1.00 85.60  ? 525 TYR B CD1 1 
ATOM   7873  C CD2 . TYR B 1 465 ? -13.963  -13.354 99.634  1.00 88.44  ? 525 TYR B CD2 1 
ATOM   7874  C CE1 . TYR B 1 465 ? -15.456  -15.345 100.823 1.00 85.18  ? 525 TYR B CE1 1 
ATOM   7875  C CE2 . TYR B 1 465 ? -13.358  -14.230 100.527 1.00 86.27  ? 525 TYR B CE2 1 
ATOM   7876  C CZ  . TYR B 1 465 ? -14.108  -15.232 101.119 1.00 82.59  ? 525 TYR B CZ  1 
ATOM   7877  O OH  . TYR B 1 465 ? -13.528  -16.083 102.009 1.00 80.93  ? 525 TYR B OH  1 
ATOM   7878  N N   . GLU B 1 466 ? -16.404  -9.901  100.883 1.00 93.86  ? 526 GLU B N   1 
ATOM   7879  C CA  . GLU B 1 466 ? -15.900  -8.733  101.659 1.00 102.36 ? 526 GLU B CA  1 
ATOM   7880  C C   . GLU B 1 466 ? -15.781  -7.481  100.778 1.00 88.80  ? 526 GLU B C   1 
ATOM   7881  O O   . GLU B 1 466 ? -14.692  -6.897  100.680 1.00 89.92  ? 526 GLU B O   1 
ATOM   7882  C CB  . GLU B 1 466 ? -14.633  -9.040  102.484 1.00 117.68 ? 526 GLU B CB  1 
ATOM   7883  C CG  . GLU B 1 466 ? -13.543  -9.957  101.904 1.00 113.01 ? 526 GLU B CG  1 
ATOM   7884  C CD  . GLU B 1 466 ? -13.391  -11.311 102.612 1.00 101.46 ? 526 GLU B CD  1 
ATOM   7885  O OE1 . GLU B 1 466 ? -14.426  -11.918 102.879 1.00 92.47  ? 526 GLU B OE1 1 
ATOM   7886  O OE2 . GLU B 1 466 ? -12.251  -11.764 102.890 1.00 89.17  ? 526 GLU B OE2 1 
ATOM   7887  N N   . GLY B 1 467 ? -16.900  -7.063  100.195 1.00 83.91  ? 527 GLY B N   1 
ATOM   7888  C CA  . GLY B 1 467 ? -17.080  -5.709  99.620  1.00 81.40  ? 527 GLY B CA  1 
ATOM   7889  C C   . GLY B 1 467 ? -16.388  -5.572  98.287  1.00 81.80  ? 527 GLY B C   1 
ATOM   7890  O O   . GLY B 1 467 ? -16.185  -4.413  97.840  1.00 79.27  ? 527 GLY B O   1 
ATOM   7891  N N   . LYS B 1 468 ? -16.077  -6.721  97.676  1.00 90.25  ? 528 LYS B N   1 
ATOM   7892  C CA  . LYS B 1 468 ? -15.524  -6.830  96.301  1.00 102.01 ? 528 LYS B CA  1 
ATOM   7893  C C   . LYS B 1 468 ? -16.465  -7.723  95.470  1.00 101.60 ? 528 LYS B C   1 
ATOM   7894  O O   . LYS B 1 468 ? -17.077  -8.663  96.040  1.00 86.22  ? 528 LYS B O   1 
ATOM   7895  C CB  . LYS B 1 468 ? -14.099  -7.378  96.372  1.00 106.69 ? 528 LYS B CB  1 
ATOM   7896  C CG  . LYS B 1 468 ? -12.958  -6.409  96.079  1.00 110.12 ? 528 LYS B CG  1 
ATOM   7897  C CD  . LYS B 1 468 ? -11.799  -7.063  95.310  1.00 113.82 ? 528 LYS B CD  1 
ATOM   7898  C CE  . LYS B 1 468 ? -11.968  -7.029  93.799  1.00 109.26 ? 528 LYS B CE  1 
ATOM   7899  N NZ  . LYS B 1 468 ? -10.945  -7.838  93.094  1.00 101.31 ? 528 LYS B NZ  1 
ATOM   7900  N N   . THR B 1 469 ? -16.632  -7.371  94.191  1.00 95.82  ? 529 THR B N   1 
ATOM   7901  C CA  . THR B 1 469 ? -17.554  -8.009  93.204  1.00 79.69  ? 529 THR B CA  1 
ATOM   7902  C C   . THR B 1 469 ? -16.732  -8.877  92.239  1.00 71.45  ? 529 THR B C   1 
ATOM   7903  O O   . THR B 1 469 ? -15.825  -8.330  91.575  1.00 71.83  ? 529 THR B O   1 
ATOM   7904  C CB  . THR B 1 469 ? -18.316  -6.931  92.416  1.00 78.22  ? 529 THR B CB  1 
ATOM   7905  O OG1 . THR B 1 469 ? -18.970  -6.027  93.302  1.00 83.84  ? 529 THR B OG1 1 
ATOM   7906  C CG2 . THR B 1 469 ? -19.331  -7.529  91.474  1.00 85.41  ? 529 THR B CG2 1 
ATOM   7907  N N   . PHE B 1 470 ? -17.044  -10.170 92.138  1.00 71.29  ? 530 PHE B N   1 
ATOM   7908  C CA  . PHE B 1 470 ? -16.414  -11.129 91.189  1.00 74.45  ? 530 PHE B CA  1 
ATOM   7909  C C   . PHE B 1 470 ? -17.418  -11.507 90.097  1.00 76.58  ? 530 PHE B C   1 
ATOM   7910  O O   . PHE B 1 470 ? -18.458  -12.050 90.429  1.00 91.61  ? 530 PHE B O   1 
ATOM   7911  C CB  . PHE B 1 470 ? -15.849  -12.334 91.938  1.00 69.11  ? 530 PHE B CB  1 
ATOM   7912  C CG  . PHE B 1 470 ? -14.593  -11.980 92.688  1.00 77.81  ? 530 PHE B CG  1 
ATOM   7913  C CD1 . PHE B 1 470 ? -13.825  -10.882 92.297  1.00 104.92 ? 530 PHE B CD1 1 
ATOM   7914  C CD2 . PHE B 1 470 ? -14.199  -12.680 93.796  1.00 65.60  ? 530 PHE B CD2 1 
ATOM   7915  C CE1 . PHE B 1 470 ? -12.646  -10.559 92.951  1.00 92.12  ? 530 PHE B CE1 1 
ATOM   7916  C CE2 . PHE B 1 470 ? -13.027  -12.354 94.453  1.00 69.71  ? 530 PHE B CE2 1 
ATOM   7917  C CZ  . PHE B 1 470 ? -12.256  -11.295 94.040  1.00 80.41  ? 530 PHE B CZ  1 
ATOM   7918  N N   . VAL B 1 471 ? -17.098  -11.189 88.844  1.00 68.67  ? 531 VAL B N   1 
ATOM   7919  C CA  . VAL B 1 471 ? -17.916  -11.496 87.641  1.00 63.04  ? 531 VAL B CA  1 
ATOM   7920  C C   . VAL B 1 471 ? -17.326  -12.737 86.987  1.00 54.27  ? 531 VAL B C   1 
ATOM   7921  O O   . VAL B 1 471 ? -16.392  -12.637 86.197  1.00 74.35  ? 531 VAL B O   1 
ATOM   7922  C CB  . VAL B 1 471 ? -17.869  -10.307 86.664  1.00 68.41  ? 531 VAL B CB  1 
ATOM   7923  C CG1 . VAL B 1 471 ? -18.721  -10.583 85.434  1.00 59.31  ? 531 VAL B CG1 1 
ATOM   7924  C CG2 . VAL B 1 471 ? -18.240  -8.997  87.340  1.00 71.41  ? 531 VAL B CG2 1 
ATOM   7925  N N   . PRO B 1 472 ? -17.798  -13.956 87.287  1.00 44.63  ? 532 PRO B N   1 
ATOM   7926  C CA  . PRO B 1 472 ? -17.169  -15.159 86.744  1.00 46.63  ? 532 PRO B CA  1 
ATOM   7927  C C   . PRO B 1 472 ? -17.414  -15.154 85.230  1.00 46.97  ? 532 PRO B C   1 
ATOM   7928  O O   . PRO B 1 472 ? -18.465  -14.768 84.836  1.00 51.52  ? 532 PRO B O   1 
ATOM   7929  C CB  . PRO B 1 472 ? -17.862  -16.320 87.440  1.00 40.21  ? 532 PRO B CB  1 
ATOM   7930  C CG  . PRO B 1 472 ? -19.214  -15.730 87.807  1.00 45.56  ? 532 PRO B CG  1 
ATOM   7931  C CD  . PRO B 1 472 ? -18.985  -14.252 88.079  1.00 45.42  ? 532 PRO B CD  1 
ATOM   7932  N N   . GLY B 1 473 ? -16.415  -15.505 84.433  1.00 50.66  ? 533 GLY B N   1 
ATOM   7933  C CA  . GLY B 1 473 ? -16.576  -15.575 82.980  1.00 53.39  ? 533 GLY B CA  1 
ATOM   7934  C C   . GLY B 1 473 ? -17.412  -16.781 82.601  1.00 54.63  ? 533 GLY B C   1 
ATOM   7935  O O   . GLY B 1 473 ? -17.458  -17.757 83.398  1.00 39.35  ? 533 GLY B O   1 
ATOM   7936  N N   . GLN B 1 474 ? -18.017  -16.722 81.409  1.00 63.03  ? 534 GLN B N   1 
ATOM   7937  C CA  . GLN B 1 474 ? -18.771  -17.849 80.811  1.00 58.95  ? 534 GLN B CA  1 
ATOM   7938  C C   . GLN B 1 474 ? -17.915  -18.514 79.732  1.00 57.71  ? 534 GLN B C   1 
ATOM   7939  O O   . GLN B 1 474 ? -17.813  -18.015 78.595  1.00 53.15  ? 534 GLN B O   1 
ATOM   7940  C CB  . GLN B 1 474 ? -20.129  -17.408 80.267  1.00 73.05  ? 534 GLN B CB  1 
ATOM   7941  C CG  . GLN B 1 474 ? -21.150  -18.530 80.334  1.00 71.55  ? 534 GLN B CG  1 
ATOM   7942  C CD  . GLN B 1 474 ? -22.479  -18.153 79.750  1.00 67.47  ? 534 GLN B CD  1 
ATOM   7943  O OE1 . GLN B 1 474 ? -22.890  -16.998 79.773  1.00 84.16  ? 534 GLN B OE1 1 
ATOM   7944  N NE2 . GLN B 1 474 ? -23.188  -19.153 79.288  1.00 61.34  ? 534 GLN B NE2 1 
ATOM   7945  N N   . SER B 1 475 ? -17.317  -19.636 80.104  1.00 59.18  ? 535 SER B N   1 
ATOM   7946  C CA  . SER B 1 475 ? -16.500  -20.502 79.243  1.00 56.09  ? 535 SER B CA  1 
ATOM   7947  C C   . SER B 1 475 ? -17.458  -21.440 78.511  1.00 56.46  ? 535 SER B C   1 
ATOM   7948  O O   . SER B 1 475 ? -17.511  -22.620 78.864  1.00 56.23  ? 535 SER B O   1 
ATOM   7949  C CB  . SER B 1 475 ? -15.500  -21.216 80.087  1.00 58.16  ? 535 SER B CB  1 
ATOM   7950  O OG  . SER B 1 475 ? -14.937  -22.312 79.402  1.00 71.90  ? 535 SER B OG  1 
ATOM   7951  N N   . ASN B 1 476 ? -18.190  -20.885 77.543  1.00 56.96  ? 536 ASN B N   1 
ATOM   7952  C CA  . ASN B 1 476 ? -19.213  -21.557 76.691  1.00 59.36  ? 536 ASN B CA  1 
ATOM   7953  C C   . ASN B 1 476 ? -18.882  -21.294 75.208  1.00 70.93  ? 536 ASN B C   1 
ATOM   7954  O O   . ASN B 1 476 ? -18.515  -20.135 74.850  1.00 77.04  ? 536 ASN B O   1 
ATOM   7955  C CB  . ASN B 1 476 ? -20.619  -21.053 77.023  1.00 57.40  ? 536 ASN B CB  1 
ATOM   7956  C CG  . ASN B 1 476 ? -21.743  -21.849 76.388  1.00 57.68  ? 536 ASN B CG  1 
ATOM   7957  O OD1 . ASN B 1 476 ? -21.983  -21.765 75.181  1.00 47.23  ? 536 ASN B OD1 1 
ATOM   7958  N ND2 . ASN B 1 476 ? -22.452  -22.611 77.212  1.00 63.00  ? 536 ASN B ND2 1 
ATOM   7959  N N   . ASN B 1 477 ? -19.035  -22.312 74.356  1.00 65.45  ? 537 ASN B N   1 
ATOM   7960  C CA  . ASN B 1 477 ? -18.525  -22.278 72.960  1.00 56.98  ? 537 ASN B CA  1 
ATOM   7961  C C   . ASN B 1 477 ? -19.250  -21.193 72.138  1.00 48.39  ? 537 ASN B C   1 
ATOM   7962  O O   . ASN B 1 477 ? -18.831  -20.950 71.014  1.00 52.51  ? 537 ASN B O   1 
ATOM   7963  C CB  . ASN B 1 477 ? -18.568  -23.676 72.341  1.00 59.65  ? 537 ASN B CB  1 
ATOM   7964  C CG  . ASN B 1 477 ? -19.943  -24.300 72.410  1.00 59.84  ? 537 ASN B CG  1 
ATOM   7965  O OD1 . ASN B 1 477 ? -20.948  -23.608 72.256  1.00 61.82  ? 537 ASN B OD1 1 
ATOM   7966  N ND2 . ASN B 1 477 ? -19.992  -25.598 72.647  1.00 60.27  ? 537 ASN B ND2 1 
ATOM   7967  N N   . ALA B 1 478 ? -20.274  -20.547 72.683  1.00 48.23  ? 538 ALA B N   1 
ATOM   7968  C CA  . ALA B 1 478 ? -21.006  -19.398 72.089  1.00 55.13  ? 538 ALA B CA  1 
ATOM   7969  C C   . ALA B 1 478 ? -20.093  -18.182 71.832  1.00 51.42  ? 538 ALA B C   1 
ATOM   7970  O O   . ALA B 1 478 ? -20.475  -17.296 71.057  1.00 42.95  ? 538 ALA B O   1 
ATOM   7971  C CB  . ALA B 1 478 ? -22.114  -18.978 73.037  1.00 56.31  ? 538 ALA B CB  1 
ATOM   7972  N N   . TYR B 1 479 ? -18.965  -18.088 72.528  1.00 47.74  ? 539 TYR B N   1 
ATOM   7973  C CA  . TYR B 1 479 ? -17.932  -17.043 72.316  1.00 48.66  ? 539 TYR B CA  1 
ATOM   7974  C C   . TYR B 1 479 ? -17.100  -17.329 71.045  1.00 57.60  ? 539 TYR B C   1 
ATOM   7975  O O   . TYR B 1 479 ? -16.482  -16.400 70.498  1.00 50.61  ? 539 TYR B O   1 
ATOM   7976  C CB  . TYR B 1 479 ? -17.043  -16.997 73.556  1.00 44.62  ? 539 TYR B CB  1 
ATOM   7977  C CG  . TYR B 1 479 ? -17.412  -16.009 74.628  1.00 41.92  ? 539 TYR B CG  1 
ATOM   7978  C CD1 . TYR B 1 479 ? -17.275  -14.658 74.388  1.00 45.69  ? 539 TYR B CD1 1 
ATOM   7979  C CD2 . TYR B 1 479 ? -17.797  -16.403 75.899  1.00 43.72  ? 539 TYR B CD2 1 
ATOM   7980  C CE1 . TYR B 1 479 ? -17.565  -13.709 75.359  1.00 49.28  ? 539 TYR B CE1 1 
ATOM   7981  C CE2 . TYR B 1 479 ? -18.082  -15.468 76.890  1.00 50.16  ? 539 TYR B CE2 1 
ATOM   7982  C CZ  . TYR B 1 479 ? -17.965  -14.109 76.619  1.00 48.54  ? 539 TYR B CZ  1 
ATOM   7983  O OH  . TYR B 1 479 ? -18.233  -13.131 77.540  1.00 47.03  ? 539 TYR B OH  1 
ATOM   7984  N N   . ILE B 1 480 ? -17.053  -18.603 70.602  1.00 68.98  ? 540 ILE B N   1 
ATOM   7985  C CA  . ILE B 1 480 ? -16.136  -19.140 69.539  1.00 58.73  ? 540 ILE B CA  1 
ATOM   7986  C C   . ILE B 1 480 ? -16.922  -19.355 68.235  1.00 57.69  ? 540 ILE B C   1 
ATOM   7987  O O   . ILE B 1 480 ? -16.499  -18.755 67.230  1.00 70.56  ? 540 ILE B O   1 
ATOM   7988  C CB  . ILE B 1 480 ? -15.416  -20.429 70.009  1.00 56.11  ? 540 ILE B CB  1 
ATOM   7989  C CG1 . ILE B 1 480 ? -14.371  -20.151 71.105  1.00 61.71  ? 540 ILE B CG1 1 
ATOM   7990  C CG2 . ILE B 1 480 ? -14.799  -21.189 68.840  1.00 51.54  ? 540 ILE B CG2 1 
ATOM   7991  C CD1 . ILE B 1 480 ? -13.154  -19.348 70.674  1.00 64.27  ? 540 ILE B CD1 1 
ATOM   7992  N N   . PHE B 1 481 ? -17.985  -20.183 68.220  1.00 51.19  ? 541 PHE B N   1 
ATOM   7993  C CA  . PHE B 1 481 ? -18.555  -20.767 66.969  1.00 49.16  ? 541 PHE B CA  1 
ATOM   7994  C C   . PHE B 1 481 ? -19.148  -19.647 66.111  1.00 51.78  ? 541 PHE B C   1 
ATOM   7995  O O   . PHE B 1 481 ? -19.055  -19.719 64.893  1.00 58.76  ? 541 PHE B O   1 
ATOM   7996  C CB  . PHE B 1 481 ? -19.478  -21.978 67.209  1.00 45.19  ? 541 PHE B CB  1 
ATOM   7997  C CG  . PHE B 1 481 ? -20.830  -21.669 67.799  1.00 49.04  ? 541 PHE B CG  1 
ATOM   7998  C CD1 . PHE B 1 481 ? -21.781  -20.972 67.069  1.00 55.23  ? 541 PHE B CD1 1 
ATOM   7999  C CD2 . PHE B 1 481 ? -21.146  -22.028 69.101  1.00 52.00  ? 541 PHE B CD2 1 
ATOM   8000  C CE1 . PHE B 1 481 ? -23.004  -20.638 67.632  1.00 57.93  ? 541 PHE B CE1 1 
ATOM   8001  C CE2 . PHE B 1 481 ? -22.378  -21.708 69.649  1.00 57.09  ? 541 PHE B CE2 1 
ATOM   8002  C CZ  . PHE B 1 481 ? -23.317  -21.036 68.908  1.00 54.86  ? 541 PHE B CZ  1 
ATOM   8003  N N   . PRO B 1 482 ? -19.796  -18.589 66.654  1.00 54.07  ? 542 PRO B N   1 
ATOM   8004  C CA  . PRO B 1 482 ? -20.276  -17.485 65.826  1.00 56.24  ? 542 PRO B CA  1 
ATOM   8005  C C   . PRO B 1 482 ? -19.167  -16.846 64.987  1.00 51.01  ? 542 PRO B C   1 
ATOM   8006  O O   . PRO B 1 482 ? -19.383  -16.705 63.817  1.00 55.61  ? 542 PRO B O   1 
ATOM   8007  C CB  . PRO B 1 482 ? -20.838  -16.470 66.827  1.00 57.72  ? 542 PRO B CB  1 
ATOM   8008  C CG  . PRO B 1 482 ? -21.277  -17.351 67.950  1.00 63.43  ? 542 PRO B CG  1 
ATOM   8009  C CD  . PRO B 1 482 ? -20.198  -18.409 68.052  1.00 60.28  ? 542 PRO B CD  1 
ATOM   8010  N N   . GLY B 1 483 ? -18.044  -16.469 65.595  1.00 47.55  ? 543 GLY B N   1 
ATOM   8011  C CA  . GLY B 1 483 ? -16.862  -15.996 64.847  1.00 51.09  ? 543 GLY B CA  1 
ATOM   8012  C C   . GLY B 1 483 ? -16.237  -17.060 63.927  1.00 48.87  ? 543 GLY B C   1 
ATOM   8013  O O   . GLY B 1 483 ? -15.883  -16.731 62.776  1.00 38.81  ? 543 GLY B O   1 
ATOM   8014  N N   . LEU B 1 484 ? -16.073  -18.301 64.407  1.00 52.96  ? 544 LEU B N   1 
ATOM   8015  C CA  . LEU B 1 484 ? -15.417  -19.399 63.649  1.00 49.88  ? 544 LEU B CA  1 
ATOM   8016  C C   . LEU B 1 484 ? -16.266  -19.750 62.427  1.00 50.35  ? 544 LEU B C   1 
ATOM   8017  O O   . LEU B 1 484 ? -15.684  -19.978 61.356  1.00 62.94  ? 544 LEU B O   1 
ATOM   8018  C CB  . LEU B 1 484 ? -15.234  -20.610 64.553  1.00 54.69  ? 544 LEU B CB  1 
ATOM   8019  C CG  . LEU B 1 484 ? -14.709  -21.888 63.897  1.00 58.80  ? 544 LEU B CG  1 
ATOM   8020  C CD1 . LEU B 1 484 ? -13.641  -22.488 64.790  1.00 58.98  ? 544 LEU B CD1 1 
ATOM   8021  C CD2 . LEU B 1 484 ? -15.812  -22.927 63.694  1.00 59.16  ? 544 LEU B CD2 1 
ATOM   8022  N N   . GLY B 1 485 ? -17.588  -19.791 62.576  1.00 47.72  ? 545 GLY B N   1 
ATOM   8023  C CA  . GLY B 1 485 ? -18.522  -20.044 61.459  1.00 47.03  ? 545 GLY B CA  1 
ATOM   8024  C C   . GLY B 1 485 ? -18.425  -18.954 60.400  1.00 46.22  ? 545 GLY B C   1 
ATOM   8025  O O   . GLY B 1 485 ? -18.148  -19.306 59.242  1.00 52.93  ? 545 GLY B O   1 
ATOM   8026  N N   . LEU B 1 486 ? -18.607  -17.683 60.789  1.00 44.23  ? 546 LEU B N   1 
ATOM   8027  C CA  . LEU B 1 486 ? -18.553  -16.486 59.908  1.00 44.26  ? 546 LEU B CA  1 
ATOM   8028  C C   . LEU B 1 486 ? -17.247  -16.543 59.123  1.00 52.00  ? 546 LEU B C   1 
ATOM   8029  O O   . LEU B 1 486 ? -17.254  -16.261 57.898  1.00 51.19  ? 546 LEU B O   1 
ATOM   8030  C CB  . LEU B 1 486 ? -18.599  -15.196 60.736  1.00 44.33  ? 546 LEU B CB  1 
ATOM   8031  C CG  . LEU B 1 486 ? -18.530  -13.892 59.925  1.00 43.24  ? 546 LEU B CG  1 
ATOM   8032  C CD1 . LEU B 1 486 ? -19.752  -13.737 59.047  1.00 47.82  ? 546 LEU B CD1 1 
ATOM   8033  C CD2 . LEU B 1 486 ? -18.428  -12.668 60.804  1.00 40.28  ? 546 LEU B CD2 1 
ATOM   8034  N N   . GLY B 1 487 ? -16.163  -16.918 59.809  1.00 59.39  ? 547 GLY B N   1 
ATOM   8035  C CA  . GLY B 1 487 ? -14.823  -17.033 59.192  1.00 60.15  ? 547 GLY B CA  1 
ATOM   8036  C C   . GLY B 1 487 ? -14.774  -18.085 58.097  1.00 53.72  ? 547 GLY B C   1 
ATOM   8037  O O   . GLY B 1 487 ? -14.342  -17.734 56.991  1.00 47.04  ? 547 GLY B O   1 
ATOM   8038  N N   . LEU B 1 488 ? -15.191  -19.324 58.397  1.00 50.83  ? 548 LEU B N   1 
ATOM   8039  C CA  . LEU B 1 488 ? -15.239  -20.425 57.401  1.00 55.13  ? 548 LEU B CA  1 
ATOM   8040  C C   . LEU B 1 488 ? -16.058  -19.977 56.175  1.00 58.22  ? 548 LEU B C   1 
ATOM   8041  O O   . LEU B 1 488 ? -15.668  -20.304 55.017  1.00 62.08  ? 548 LEU B O   1 
ATOM   8042  C CB  . LEU B 1 488 ? -15.836  -21.673 58.061  1.00 51.69  ? 548 LEU B CB  1 
ATOM   8043  C CG  . LEU B 1 488 ? -14.973  -22.328 59.127  1.00 51.16  ? 548 LEU B CG  1 
ATOM   8044  C CD1 . LEU B 1 488 ? -15.651  -23.553 59.713  1.00 53.27  ? 548 LEU B CD1 1 
ATOM   8045  C CD2 . LEU B 1 488 ? -13.633  -22.718 58.545  1.00 59.45  ? 548 LEU B CD2 1 
ATOM   8046  N N   . VAL B 1 489 ? -17.154  -19.250 56.396  1.00 54.17  ? 549 VAL B N   1 
ATOM   8047  C CA  . VAL B 1 489 ? -18.045  -18.782 55.295  1.00 52.93  ? 549 VAL B CA  1 
ATOM   8048  C C   . VAL B 1 489 ? -17.326  -17.681 54.522  1.00 47.19  ? 549 VAL B C   1 
ATOM   8049  O O   . VAL B 1 489 ? -17.051  -17.946 53.379  1.00 58.13  ? 549 VAL B O   1 
ATOM   8050  C CB  . VAL B 1 489 ? -19.436  -18.348 55.808  1.00 61.26  ? 549 VAL B CB  1 
ATOM   8051  C CG1 . VAL B 1 489 ? -20.259  -17.621 54.737  1.00 56.19  ? 549 VAL B CG1 1 
ATOM   8052  C CG2 . VAL B 1 489 ? -20.199  -19.539 56.394  1.00 57.47  ? 549 VAL B CG2 1 
ATOM   8053  N N   . ILE B 1 490 ? -16.974  -16.535 55.118  1.00 47.17  ? 550 ILE B N   1 
ATOM   8054  C CA  . ILE B 1 490 ? -16.529  -15.324 54.348  1.00 51.31  ? 550 ILE B CA  1 
ATOM   8055  C C   . ILE B 1 490 ? -15.210  -15.594 53.601  1.00 53.65  ? 550 ILE B C   1 
ATOM   8056  O O   . ILE B 1 490 ? -14.807  -14.720 52.805  1.00 58.16  ? 550 ILE B O   1 
ATOM   8057  C CB  . ILE B 1 490 ? -16.394  -14.078 55.247  1.00 57.83  ? 550 ILE B CB  1 
ATOM   8058  C CG1 . ILE B 1 490 ? -15.295  -14.230 56.312  1.00 58.66  ? 550 ILE B CG1 1 
ATOM   8059  C CG2 . ILE B 1 490 ? -17.741  -13.730 55.850  1.00 59.28  ? 550 ILE B CG2 1 
ATOM   8060  C CD1 . ILE B 1 490 ? -15.191  -13.037 57.242  1.00 59.27  ? 550 ILE B CD1 1 
ATOM   8061  N N   . SER B 1 491 ? -14.531  -16.709 53.907  1.00 50.54  ? 551 SER B N   1 
ATOM   8062  C CA  . SER B 1 491 ? -13.245  -17.153 53.310  1.00 46.75  ? 551 SER B CA  1 
ATOM   8063  C C   . SER B 1 491 ? -13.512  -18.259 52.314  1.00 47.04  ? 551 SER B C   1 
ATOM   8064  O O   . SER B 1 491 ? -12.632  -18.560 51.504  1.00 59.99  ? 551 SER B O   1 
ATOM   8065  C CB  . SER B 1 491 ? -12.274  -17.651 54.367  1.00 56.28  ? 551 SER B CB  1 
ATOM   8066  O OG  . SER B 1 491 ? -12.479  -19.028 54.717  1.00 49.27  ? 551 SER B OG  1 
ATOM   8067  N N   . GLY B 1 492 ? -14.667  -18.897 52.415  1.00 49.46  ? 552 GLY B N   1 
ATOM   8068  C CA  . GLY B 1 492 ? -15.002  -20.063 51.578  1.00 54.53  ? 552 GLY B CA  1 
ATOM   8069  C C   . GLY B 1 492 ? -14.136  -21.259 51.915  1.00 50.01  ? 552 GLY B C   1 
ATOM   8070  O O   . GLY B 1 492 ? -13.870  -22.055 51.012  1.00 52.30  ? 552 GLY B O   1 
ATOM   8071  N N   . ALA B 1 493 ? -13.737  -21.407 53.171  1.00 47.32  ? 553 ALA B N   1 
ATOM   8072  C CA  . ALA B 1 493 ? -12.999  -22.597 53.643  1.00 52.35  ? 553 ALA B CA  1 
ATOM   8073  C C   . ALA B 1 493 ? -13.779  -23.870 53.278  1.00 48.62  ? 553 ALA B C   1 
ATOM   8074  O O   . ALA B 1 493 ? -15.001  -23.848 53.336  1.00 58.43  ? 553 ALA B O   1 
ATOM   8075  C CB  . ALA B 1 493 ? -12.777  -22.489 55.120  1.00 51.64  ? 553 ALA B CB  1 
ATOM   8076  N N   . VAL B 1 494 ? -13.076  -24.917 52.888  1.00 45.44  ? 554 VAL B N   1 
ATOM   8077  C CA  . VAL B 1 494 ? -13.648  -26.209 52.399  1.00 55.19  ? 554 VAL B CA  1 
ATOM   8078  C C   . VAL B 1 494 ? -13.368  -27.302 53.431  1.00 55.37  ? 554 VAL B C   1 
ATOM   8079  O O   . VAL B 1 494 ? -13.832  -28.430 53.235  1.00 57.52  ? 554 VAL B O   1 
ATOM   8080  C CB  . VAL B 1 494 ? -13.041  -26.620 51.036  1.00 59.85  ? 554 VAL B CB  1 
ATOM   8081  C CG1 . VAL B 1 494 ? -13.173  -25.522 49.996  1.00 65.77  ? 554 VAL B CG1 1 
ATOM   8082  C CG2 . VAL B 1 494 ? -11.583  -27.029 51.129  1.00 56.02  ? 554 VAL B CG2 1 
ATOM   8083  N N   . ARG B 1 495 ? -12.545  -26.993 54.434  1.00 57.63  ? 555 ARG B N   1 
ATOM   8084  C CA  . ARG B 1 495 ? -12.191  -27.945 55.511  1.00 58.19  ? 555 ARG B CA  1 
ATOM   8085  C C   . ARG B 1 495 ? -11.933  -27.189 56.812  1.00 61.73  ? 555 ARG B C   1 
ATOM   8086  O O   . ARG B 1 495 ? -11.589  -25.995 56.757  1.00 64.91  ? 555 ARG B O   1 
ATOM   8087  C CB  . ARG B 1 495 ? -10.967  -28.763 55.127  1.00 67.15  ? 555 ARG B CB  1 
ATOM   8088  C CG  . ARG B 1 495 ? -11.309  -30.187 54.731  1.00 78.80  ? 555 ARG B CG  1 
ATOM   8089  C CD  . ARG B 1 495 ? -10.261  -31.119 55.290  1.00 89.23  ? 555 ARG B CD  1 
ATOM   8090  N NE  . ARG B 1 495 ? -10.042  -32.152 54.298  1.00 97.48  ? 555 ARG B NE  1 
ATOM   8091  C CZ  . ARG B 1 495 ? -9.248   -32.029 53.229  1.00 92.44  ? 555 ARG B CZ  1 
ATOM   8092  N NH1 . ARG B 1 495 ? -8.576   -30.907 53.015  1.00 96.79  ? 555 ARG B NH1 1 
ATOM   8093  N NH2 . ARG B 1 495 ? -9.121   -33.037 52.380  1.00 85.38  ? 555 ARG B NH2 1 
ATOM   8094  N N   . VAL B 1 496 ? -12.128  -27.877 57.937  1.00 61.24  ? 556 VAL B N   1 
ATOM   8095  C CA  . VAL B 1 496 ? -11.770  -27.394 59.296  1.00 56.20  ? 556 VAL B CA  1 
ATOM   8096  C C   . VAL B 1 496 ? -10.430  -28.020 59.691  1.00 56.31  ? 556 VAL B C   1 
ATOM   8097  O O   . VAL B 1 496 ? -10.271  -29.264 59.540  1.00 40.43  ? 556 VAL B O   1 
ATOM   8098  C CB  . VAL B 1 496 ? -12.898  -27.719 60.274  1.00 57.65  ? 556 VAL B CB  1 
ATOM   8099  C CG1 . VAL B 1 496 ? -12.537  -27.352 61.697  1.00 58.34  ? 556 VAL B CG1 1 
ATOM   8100  C CG2 . VAL B 1 496 ? -14.184  -27.029 59.826  1.00 63.03  ? 556 VAL B CG2 1 
ATOM   8101  N N   . HIS B 1 497 ? -9.481   -27.163 60.099  1.00 62.78  ? 557 HIS B N   1 
ATOM   8102  C CA  . HIS B 1 497 ? -8.097   -27.558 60.483  1.00 75.04  ? 557 HIS B CA  1 
ATOM   8103  C C   . HIS B 1 497 ? -7.875   -27.226 61.961  1.00 72.44  ? 557 HIS B C   1 
ATOM   8104  O O   . HIS B 1 497 ? -8.181   -26.089 62.357  1.00 66.24  ? 557 HIS B O   1 
ATOM   8105  C CB  . HIS B 1 497 ? -7.028   -26.896 59.586  1.00 76.73  ? 557 HIS B CB  1 
ATOM   8106  C CG  . HIS B 1 497 ? -5.705   -27.611 59.582  1.00 77.30  ? 557 HIS B CG  1 
ATOM   8107  N ND1 . HIS B 1 497 ? -4.804   -27.557 60.639  1.00 73.64  ? 557 HIS B ND1 1 
ATOM   8108  C CD2 . HIS B 1 497 ? -5.120   -28.372 58.633  1.00 72.60  ? 557 HIS B CD2 1 
ATOM   8109  C CE1 . HIS B 1 497 ? -3.731   -28.256 60.337  1.00 78.58  ? 557 HIS B CE1 1 
ATOM   8110  N NE2 . HIS B 1 497 ? -3.905   -28.775 59.116  1.00 83.77  ? 557 HIS B NE2 1 
ATOM   8111  N N   . GLU B 1 498 ? -7.343   -28.178 62.728  1.00 63.57  ? 558 GLU B N   1 
ATOM   8112  C CA  . GLU B 1 498 ? -6.971   -27.985 64.149  1.00 65.06  ? 558 GLU B CA  1 
ATOM   8113  C C   . GLU B 1 498 ? -6.346   -26.594 64.296  1.00 63.32  ? 558 GLU B C   1 
ATOM   8114  O O   . GLU B 1 498 ? -6.671   -25.913 65.256  1.00 82.96  ? 558 GLU B O   1 
ATOM   8115  C CB  . GLU B 1 498 ? -6.087   -29.129 64.673  1.00 73.76  ? 558 GLU B CB  1 
ATOM   8116  C CG  . GLU B 1 498 ? -5.044   -29.651 63.711  1.00 86.47  ? 558 GLU B CG  1 
ATOM   8117  C CD  . GLU B 1 498 ? -5.486   -30.809 62.812  1.00 99.96  ? 558 GLU B CD  1 
ATOM   8118  O OE1 . GLU B 1 498 ? -6.334   -30.617 61.888  1.00 77.94  ? 558 GLU B OE1 1 
ATOM   8119  O OE2 . GLU B 1 498 ? -4.986   -31.917 63.043  1.00 120.62 ? 558 GLU B OE2 1 
ATOM   8120  N N   . ASP B 1 499 ? -5.556   -26.136 63.338  1.00 67.48  ? 559 ASP B N   1 
ATOM   8121  C CA  . ASP B 1 499 ? -4.887   -24.808 63.420  1.00 75.62  ? 559 ASP B CA  1 
ATOM   8122  C C   . ASP B 1 499 ? -5.903   -23.649 63.465  1.00 67.13  ? 559 ASP B C   1 
ATOM   8123  O O   . ASP B 1 499 ? -5.501   -22.569 63.926  1.00 74.83  ? 559 ASP B O   1 
ATOM   8124  C CB  . ASP B 1 499 ? -3.885   -24.597 62.277  1.00 78.82  ? 559 ASP B CB  1 
ATOM   8125  C CG  . ASP B 1 499 ? -2.586   -25.376 62.417  1.00 79.20  ? 559 ASP B CG  1 
ATOM   8126  O OD1 . ASP B 1 499 ? -2.626   -26.541 62.891  1.00 72.26  ? 559 ASP B OD1 1 
ATOM   8127  O OD2 . ASP B 1 499 ? -1.538   -24.791 62.062  1.00 82.29  ? 559 ASP B OD2 1 
ATOM   8128  N N   . MET B 1 500 ? -7.153   -23.837 63.027  1.00 62.54  ? 560 MET B N   1 
ATOM   8129  C CA  . MET B 1 500 ? -8.209   -22.774 63.028  1.00 70.42  ? 560 MET B CA  1 
ATOM   8130  C C   . MET B 1 500 ? -8.818   -22.629 64.438  1.00 67.23  ? 560 MET B C   1 
ATOM   8131  O O   . MET B 1 500 ? -9.130   -21.479 64.875  1.00 47.80  ? 560 MET B O   1 
ATOM   8132  C CB  . MET B 1 500 ? -9.339   -23.093 62.036  1.00 68.15  ? 560 MET B CB  1 
ATOM   8133  C CG  . MET B 1 500 ? -8.963   -23.008 60.580  1.00 65.18  ? 560 MET B CG  1 
ATOM   8134  S SD  . MET B 1 500 ? -10.123  -24.005 59.627  1.00 70.34  ? 560 MET B SD  1 
ATOM   8135  C CE  . MET B 1 500 ? -9.801   -23.470 57.951  1.00 72.60  ? 560 MET B CE  1 
ATOM   8136  N N   . LEU B 1 501 ? -8.996   -23.762 65.124  1.00 62.88  ? 561 LEU B N   1 
ATOM   8137  C CA  . LEU B 1 501 ? -9.404   -23.793 66.539  1.00 56.79  ? 561 LEU B CA  1 
ATOM   8138  C C   . LEU B 1 501 ? -8.414   -22.925 67.311  1.00 56.42  ? 561 LEU B C   1 
ATOM   8139  O O   . LEU B 1 501 ? -8.902   -22.080 68.097  1.00 58.42  ? 561 LEU B O   1 
ATOM   8140  C CB  . LEU B 1 501 ? -9.393   -25.237 67.039  1.00 62.75  ? 561 LEU B CB  1 
ATOM   8141  C CG  . LEU B 1 501 ? -10.622  -26.109 66.799  1.00 69.11  ? 561 LEU B CG  1 
ATOM   8142  C CD1 . LEU B 1 501 ? -11.089  -26.068 65.354  1.00 72.23  ? 561 LEU B CD1 1 
ATOM   8143  C CD2 . LEU B 1 501 ? -10.311  -27.541 67.215  1.00 64.72  ? 561 LEU B CD2 1 
ATOM   8144  N N   . LEU B 1 502 ? -7.097   -23.084 67.065  1.00 50.99  ? 562 LEU B N   1 
ATOM   8145  C CA  . LEU B 1 502 ? -6.027   -22.353 67.806  1.00 54.93  ? 562 LEU B CA  1 
ATOM   8146  C C   . LEU B 1 502 ? -6.113   -20.864 67.448  1.00 56.90  ? 562 LEU B C   1 
ATOM   8147  O O   . LEU B 1 502 ? -6.019   -20.033 68.371  1.00 60.30  ? 562 LEU B O   1 
ATOM   8148  C CB  . LEU B 1 502 ? -4.631   -22.891 67.470  1.00 58.12  ? 562 LEU B CB  1 
ATOM   8149  C CG  . LEU B 1 502 ? -4.407   -24.399 67.635  1.00 64.44  ? 562 LEU B CG  1 
ATOM   8150  C CD1 . LEU B 1 502 ? -2.985   -24.792 67.276  1.00 64.08  ? 562 LEU B CD1 1 
ATOM   8151  C CD2 . LEU B 1 502 ? -4.746   -24.863 69.037  1.00 65.68  ? 562 LEU B CD2 1 
ATOM   8152  N N   . ALA B 1 503 ? -6.308   -20.559 66.160  1.00 50.10  ? 563 ALA B N   1 
ATOM   8153  C CA  . ALA B 1 503 ? -6.384   -19.190 65.614  1.00 55.93  ? 563 ALA B CA  1 
ATOM   8154  C C   . ALA B 1 503 ? -7.499   -18.435 66.333  1.00 55.70  ? 563 ALA B C   1 
ATOM   8155  O O   . ALA B 1 503 ? -7.311   -17.246 66.688  1.00 54.96  ? 563 ALA B O   1 
ATOM   8156  C CB  . ALA B 1 503 ? -6.607   -19.240 64.119  1.00 60.19  ? 563 ALA B CB  1 
ATOM   8157  N N   . ALA B 1 504 ? -8.612   -19.132 66.540  1.00 59.22  ? 564 ALA B N   1 
ATOM   8158  C CA  . ALA B 1 504 ? -9.821   -18.638 67.239  1.00 61.04  ? 564 ALA B CA  1 
ATOM   8159  C C   . ALA B 1 504 ? -9.485   -18.394 68.710  1.00 55.21  ? 564 ALA B C   1 
ATOM   8160  O O   . ALA B 1 504 ? -9.710   -17.265 69.222  1.00 56.51  ? 564 ALA B O   1 
ATOM   8161  C CB  . ALA B 1 504 ? -10.927  -19.647 67.069  1.00 60.41  ? 564 ALA B CB  1 
ATOM   8162  N N   . SER B 1 505 ? -8.950   -19.423 69.359  1.00 54.15  ? 565 SER B N   1 
ATOM   8163  C CA  . SER B 1 505 ? -8.555   -19.382 70.787  1.00 55.43  ? 565 SER B CA  1 
ATOM   8164  C C   . SER B 1 505 ? -7.709   -18.134 71.028  1.00 50.76  ? 565 SER B C   1 
ATOM   8165  O O   . SER B 1 505 ? -8.071   -17.320 71.912  1.00 48.53  ? 565 SER B O   1 
ATOM   8166  C CB  . SER B 1 505 ? -7.845   -20.647 71.183  1.00 56.31  ? 565 SER B CB  1 
ATOM   8167  O OG  . SER B 1 505 ? -8.584   -21.796 70.755  1.00 63.27  ? 565 SER B OG  1 
ATOM   8168  N N   . LYS B 1 506 ? -6.668   -17.960 70.219  1.00 54.01  ? 566 LYS B N   1 
ATOM   8169  C CA  . LYS B 1 506 ? -5.782   -16.776 70.277  1.00 58.34  ? 566 LYS B CA  1 
ATOM   8170  C C   . LYS B 1 506 ? -6.644   -15.510 70.159  1.00 51.88  ? 566 LYS B C   1 
ATOM   8171  O O   . LYS B 1 506 ? -6.452   -14.599 70.969  1.00 50.71  ? 566 LYS B O   1 
ATOM   8172  C CB  . LYS B 1 506 ? -4.682   -16.838 69.208  1.00 73.09  ? 566 LYS B CB  1 
ATOM   8173  C CG  . LYS B 1 506 ? -3.759   -15.612 69.197  1.00 88.64  ? 566 LYS B CG  1 
ATOM   8174  C CD  . LYS B 1 506 ? -2.459   -15.729 68.402  1.00 96.90  ? 566 LYS B CD  1 
ATOM   8175  C CE  . LYS B 1 506 ? -1.321   -14.903 68.976  1.00 101.22 ? 566 LYS B CE  1 
ATOM   8176  N NZ  . LYS B 1 506 ? -0.299   -15.743 69.657  1.00 100.36 ? 566 LYS B NZ  1 
ATOM   8177  N N   . ALA B 1 507 ? -7.554   -15.455 69.187  1.00 45.49  ? 567 ALA B N   1 
ATOM   8178  C CA  . ALA B 1 507 ? -8.270   -14.219 68.811  1.00 50.64  ? 567 ALA B CA  1 
ATOM   8179  C C   . ALA B 1 507 ? -9.138   -13.763 69.982  1.00 55.63  ? 567 ALA B C   1 
ATOM   8180  O O   . ALA B 1 507 ? -9.202   -12.529 70.252  1.00 61.38  ? 567 ALA B O   1 
ATOM   8181  C CB  . ALA B 1 507 ? -9.083   -14.458 67.570  1.00 52.54  ? 567 ALA B CB  1 
ATOM   8182  N N   . LEU B 1 508 ? -9.780   -14.723 70.649  1.00 50.02  ? 568 LEU B N   1 
ATOM   8183  C CA  . LEU B 1 508 ? -10.693  -14.441 71.778  1.00 52.34  ? 568 LEU B CA  1 
ATOM   8184  C C   . LEU B 1 508 ? -9.852   -13.927 72.938  1.00 54.73  ? 568 LEU B C   1 
ATOM   8185  O O   . LEU B 1 508 ? -10.185  -12.874 73.512  1.00 47.34  ? 568 LEU B O   1 
ATOM   8186  C CB  . LEU B 1 508 ? -11.437  -15.728 72.157  1.00 54.74  ? 568 LEU B CB  1 
ATOM   8187  C CG  . LEU B 1 508 ? -12.305  -15.644 73.418  1.00 50.62  ? 568 LEU B CG  1 
ATOM   8188  C CD1 . LEU B 1 508 ? -13.267  -14.465 73.335  1.00 49.02  ? 568 LEU B CD1 1 
ATOM   8189  C CD2 . LEU B 1 508 ? -13.065  -16.960 73.635  1.00 52.41  ? 568 LEU B CD2 1 
ATOM   8190  N N   . ALA B 1 509 ? -8.815   -14.695 73.272  1.00 58.74  ? 569 ALA B N   1 
ATOM   8191  C CA  . ALA B 1 509 ? -7.883   -14.422 74.381  1.00 57.41  ? 569 ALA B CA  1 
ATOM   8192  C C   . ALA B 1 509 ? -7.328   -13.003 74.217  1.00 51.76  ? 569 ALA B C   1 
ATOM   8193  O O   . ALA B 1 509 ? -7.196   -12.319 75.229  1.00 52.69  ? 569 ALA B O   1 
ATOM   8194  C CB  . ALA B 1 509 ? -6.807   -15.487 74.391  1.00 54.20  ? 569 ALA B CB  1 
ATOM   8195  N N   . ASP B 1 510 ? -7.068   -12.574 72.977  1.00 55.78  ? 570 ASP B N   1 
ATOM   8196  C CA  . ASP B 1 510 ? -6.400   -11.281 72.654  1.00 58.02  ? 570 ASP B CA  1 
ATOM   8197  C C   . ASP B 1 510 ? -7.447   -10.154 72.665  1.00 56.09  ? 570 ASP B C   1 
ATOM   8198  O O   . ASP B 1 510 ? -7.096   -9.002  72.385  1.00 54.89  ? 570 ASP B O   1 
ATOM   8199  C CB  . ASP B 1 510 ? -5.614   -11.355 71.337  1.00 61.73  ? 570 ASP B CB  1 
ATOM   8200  C CG  . ASP B 1 510 ? -4.229   -12.005 71.413  1.00 77.35  ? 570 ASP B CG  1 
ATOM   8201  O OD1 . ASP B 1 510 ? -3.940   -12.728 72.399  1.00 86.02  ? 570 ASP B OD1 1 
ATOM   8202  O OD2 . ASP B 1 510 ? -3.433   -11.809 70.471  1.00 81.83  ? 570 ASP B OD2 1 
ATOM   8203  N N   . GLN B 1 511 ? -8.708   -10.472 72.945  1.00 60.30  ? 571 GLN B N   1 
ATOM   8204  C CA  . GLN B 1 511 ? -9.790   -9.481  73.193  1.00 63.33  ? 571 GLN B CA  1 
ATOM   8205  C C   . GLN B 1 511 ? -9.938   -9.222  74.697  1.00 63.26  ? 571 GLN B C   1 
ATOM   8206  O O   . GLN B 1 511 ? -10.648  -8.242  75.064  1.00 61.72  ? 571 GLN B O   1 
ATOM   8207  C CB  . GLN B 1 511 ? -11.109  -9.973  72.571  1.00 63.29  ? 571 GLN B CB  1 
ATOM   8208  C CG  . GLN B 1 511 ? -11.088  -9.931  71.054  1.00 60.49  ? 571 GLN B CG  1 
ATOM   8209  C CD  . GLN B 1 511 ? -10.806  -8.537  70.552  1.00 59.60  ? 571 GLN B CD  1 
ATOM   8210  O OE1 . GLN B 1 511 ? -11.369  -7.575  71.061  1.00 58.44  ? 571 GLN B OE1 1 
ATOM   8211  N NE2 . GLN B 1 511 ? -9.888   -8.411  69.598  1.00 61.53  ? 571 GLN B NE2 1 
ATOM   8212  N N   . ALA B 1 512 ? -9.382   -10.112 75.532  1.00 66.63  ? 572 ALA B N   1 
ATOM   8213  C CA  . ALA B 1 512 ? -9.498   -10.095 77.020  1.00 67.55  ? 572 ALA B CA  1 
ATOM   8214  C C   . ALA B 1 512 ? -8.546   -9.022  77.548  1.00 67.48  ? 572 ALA B C   1 
ATOM   8215  O O   . ALA B 1 512 ? -7.338   -9.237  77.480  1.00 67.63  ? 572 ALA B O   1 
ATOM   8216  C CB  . ALA B 1 512 ? -9.198   -11.459 77.620  1.00 60.15  ? 572 ALA B CB  1 
ATOM   8217  N N   . THR B 1 513 ? -9.083   -7.905  78.029  1.00 73.57  ? 573 THR B N   1 
ATOM   8218  C CA  . THR B 1 513 ? -8.292   -6.762  78.544  1.00 75.93  ? 573 THR B CA  1 
ATOM   8219  C C   . THR B 1 513 ? -8.340   -6.789  80.079  1.00 77.03  ? 573 THR B C   1 
ATOM   8220  O O   . THR B 1 513 ? -8.946   -7.712  80.656  1.00 67.71  ? 573 THR B O   1 
ATOM   8221  C CB  . THR B 1 513 ? -8.818   -5.441  77.979  1.00 72.38  ? 573 THR B CB  1 
ATOM   8222  O OG1 . THR B 1 513 ? -9.798   -4.936  78.892  1.00 72.46  ? 573 THR B OG1 1 
ATOM   8223  C CG2 . THR B 1 513 ? -9.398   -5.587  76.583  1.00 72.27  ? 573 THR B CG2 1 
ATOM   8224  N N   . GLN B 1 514 ? -7.728   -5.795  80.712  1.00 85.65  ? 574 GLN B N   1 
ATOM   8225  C CA  . GLN B 1 514 ? -7.703   -5.698  82.196  1.00 91.78  ? 574 GLN B CA  1 
ATOM   8226  C C   . GLN B 1 514 ? -9.072   -5.227  82.704  1.00 84.41  ? 574 GLN B C   1 
ATOM   8227  O O   . GLN B 1 514 ? -9.366   -5.514  83.873  1.00 66.09  ? 574 GLN B O   1 
ATOM   8228  C CB  . GLN B 1 514 ? -6.545   -4.850  82.706  1.00 101.33 ? 574 GLN B CB  1 
ATOM   8229  C CG  . GLN B 1 514 ? -6.746   -3.353  82.510  1.00 102.53 ? 574 GLN B CG  1 
ATOM   8230  C CD  . GLN B 1 514 ? -5.725   -2.566  83.287  1.00 97.87  ? 574 GLN B CD  1 
ATOM   8231  O OE1 . GLN B 1 514 ? -5.172   -3.045  84.281  1.00 102.56 ? 574 GLN B OE1 1 
ATOM   8232  N NE2 . GLN B 1 514 ? -5.490   -1.341  82.842  1.00 84.51  ? 574 GLN B NE2 1 
ATOM   8233  N N   . ASP B 1 515 ? -9.862   -4.540  81.870  1.00 77.12  ? 575 ASP B N   1 
ATOM   8234  C CA  . ASP B 1 515 ? -11.214  -4.056  82.260  1.00 74.08  ? 575 ASP B CA  1 
ATOM   8235  C C   . ASP B 1 515 ? -12.015  -5.251  82.774  1.00 55.65  ? 575 ASP B C   1 
ATOM   8236  O O   . ASP B 1 515 ? -12.647  -5.108  83.839  1.00 55.43  ? 575 ASP B O   1 
ATOM   8237  C CB  . ASP B 1 515 ? -11.912  -3.324  81.112  1.00 77.33  ? 575 ASP B CB  1 
ATOM   8238  C CG  . ASP B 1 515 ? -11.109  -2.153  80.595  1.00 91.00  ? 575 ASP B CG  1 
ATOM   8239  O OD1 . ASP B 1 515 ? -9.877   -2.164  80.786  1.00 124.35 ? 575 ASP B OD1 1 
ATOM   8240  O OD2 . ASP B 1 515 ? -11.728  -1.214  80.050  1.00 90.58  ? 575 ASP B OD2 1 
ATOM   8241  N N   . ASN B 1 516 ? -11.928  -6.387  82.088  1.00 48.29  ? 576 ASN B N   1 
ATOM   8242  C CA  . ASN B 1 516 ? -12.673  -7.606  82.469  1.00 55.01  ? 576 ASN B CA  1 
ATOM   8243  C C   . ASN B 1 516 ? -11.836  -8.426  83.445  1.00 52.32  ? 576 ASN B C   1 
ATOM   8244  O O   . ASN B 1 516 ? -12.458  -9.027  84.324  1.00 59.11  ? 576 ASN B O   1 
ATOM   8245  C CB  . ASN B 1 516 ? -13.180  -8.411  81.267  1.00 69.66  ? 576 ASN B CB  1 
ATOM   8246  C CG  . ASN B 1 516 ? -12.112  -8.760  80.261  1.00 74.51  ? 576 ASN B CG  1 
ATOM   8247  O OD1 . ASN B 1 516 ? -11.784  -7.933  79.420  1.00 84.15  ? 576 ASN B OD1 1 
ATOM   8248  N ND2 . ASN B 1 516 ? -11.611  -9.988  80.314  1.00 72.35  ? 576 ASN B ND2 1 
ATOM   8249  N N   . PHE B 1 517 ? -10.502  -8.415  83.349  1.00 59.05  ? 577 PHE B N   1 
ATOM   8250  C CA  . PHE B 1 517 ? -9.608   -9.108  84.326  1.00 60.59  ? 577 PHE B CA  1 
ATOM   8251  C C   . PHE B 1 517 ? -9.751   -8.514  85.741  1.00 64.40  ? 577 PHE B C   1 
ATOM   8252  O O   . PHE B 1 517 ? -9.824   -9.297  86.698  1.00 55.79  ? 577 PHE B O   1 
ATOM   8253  C CB  . PHE B 1 517 ? -8.134   -9.063  83.935  1.00 64.19  ? 577 PHE B CB  1 
ATOM   8254  C CG  . PHE B 1 517 ? -7.747   -9.811  82.693  1.00 72.67  ? 577 PHE B CG  1 
ATOM   8255  C CD1 . PHE B 1 517 ? -8.482   -10.906 82.274  1.00 82.60  ? 577 PHE B CD1 1 
ATOM   8256  C CD2 . PHE B 1 517 ? -6.602   -9.476  81.994  1.00 72.97  ? 577 PHE B CD2 1 
ATOM   8257  C CE1 . PHE B 1 517 ? -8.121   -11.597 81.132  1.00 86.51  ? 577 PHE B CE1 1 
ATOM   8258  C CE2 . PHE B 1 517 ? -6.237   -10.178 80.858  1.00 81.07  ? 577 PHE B CE2 1 
ATOM   8259  C CZ  . PHE B 1 517 ? -6.997   -11.242 80.428  1.00 81.73  ? 577 PHE B CZ  1 
ATOM   8260  N N   . GLU B 1 518 ? -9.734   -7.179  85.862  1.00 69.68  ? 578 GLU B N   1 
ATOM   8261  C CA  . GLU B 1 518 ? -10.015  -6.425  87.114  1.00 70.40  ? 578 GLU B CA  1 
ATOM   8262  C C   . GLU B 1 518 ? -11.159  -7.104  87.873  1.00 70.92  ? 578 GLU B C   1 
ATOM   8263  O O   . GLU B 1 518 ? -10.934  -7.465  89.017  1.00 82.24  ? 578 GLU B O   1 
ATOM   8264  C CB  . GLU B 1 518 ? -10.392  -4.974  86.822  1.00 87.32  ? 578 GLU B CB  1 
ATOM   8265  C CG  . GLU B 1 518 ? -9.197   -4.032  86.775  1.00 104.54 ? 578 GLU B CG  1 
ATOM   8266  C CD  . GLU B 1 518 ? -9.517   -2.621  86.306  1.00 112.76 ? 578 GLU B CD  1 
ATOM   8267  O OE1 . GLU B 1 518 ? -10.718  -2.319  86.088  1.00 110.81 ? 578 GLU B OE1 1 
ATOM   8268  O OE2 . GLU B 1 518 ? -8.566   -1.824  86.171  1.00 113.85 ? 578 GLU B OE2 1 
ATOM   8269  N N   . LYS B 1 519 ? -12.315  -7.316  87.232  1.00 66.08  ? 579 LYS B N   1 
ATOM   8270  C CA  . LYS B 1 519 ? -13.544  -7.877  87.852  1.00 65.67  ? 579 LYS B CA  1 
ATOM   8271  C C   . LYS B 1 519 ? -13.489  -9.413  87.956  1.00 68.16  ? 579 LYS B C   1 
ATOM   8272  O O   . LYS B 1 519 ? -14.514  -9.984  88.319  1.00 70.09  ? 579 LYS B O   1 
ATOM   8273  C CB  . LYS B 1 519 ? -14.784  -7.528  87.023  1.00 71.20  ? 579 LYS B CB  1 
ATOM   8274  C CG  . LYS B 1 519 ? -14.962  -6.052  86.722  1.00 70.74  ? 579 LYS B CG  1 
ATOM   8275  C CD  . LYS B 1 519 ? -16.035  -5.803  85.700  1.00 69.83  ? 579 LYS B CD  1 
ATOM   8276  C CE  . LYS B 1 519 ? -16.354  -4.335  85.559  1.00 72.90  ? 579 LYS B CE  1 
ATOM   8277  N NZ  . LYS B 1 519 ? -15.127  -3.597  85.178  1.00 75.72  ? 579 LYS B NZ  1 
ATOM   8278  N N   . GLY B 1 520 ? -12.382  -10.065 87.595  1.00 66.79  ? 580 GLY B N   1 
ATOM   8279  C CA  . GLY B 1 520 ? -12.172  -11.510 87.806  1.00 68.44  ? 580 GLY B CA  1 
ATOM   8280  C C   . GLY B 1 520 ? -12.646  -12.363 86.637  1.00 71.31  ? 580 GLY B C   1 
ATOM   8281  O O   . GLY B 1 520 ? -12.721  -13.597 86.815  1.00 83.40  ? 580 GLY B O   1 
ATOM   8282  N N   . SER B 1 521 ? -12.916  -11.762 85.470  1.00 68.69  ? 581 SER B N   1 
ATOM   8283  C CA  . SER B 1 521 ? -13.487  -12.416 84.257  1.00 65.64  ? 581 SER B CA  1 
ATOM   8284  C C   . SER B 1 521 ? -12.403  -12.615 83.202  1.00 62.88  ? 581 SER B C   1 
ATOM   8285  O O   . SER B 1 521 ? -11.844  -11.617 82.711  1.00 50.93  ? 581 SER B O   1 
ATOM   8286  C CB  . SER B 1 521 ? -14.602  -11.614 83.648  1.00 66.93  ? 581 SER B CB  1 
ATOM   8287  O OG  . SER B 1 521 ? -15.747  -11.608 84.465  1.00 82.06  ? 581 SER B OG  1 
ATOM   8288  N N   . ILE B 1 522 ? -12.217  -13.862 82.776  1.00 61.84  ? 582 ILE B N   1 
ATOM   8289  C CA  . ILE B 1 522 ? -11.242  -14.229 81.721  1.00 52.72  ? 582 ILE B CA  1 
ATOM   8290  C C   . ILE B 1 522 ? -11.739  -13.730 80.362  1.00 61.49  ? 582 ILE B C   1 
ATOM   8291  O O   . ILE B 1 522 ? -10.909  -13.632 79.439  1.00 94.73  ? 582 ILE B O   1 
ATOM   8292  C CB  . ILE B 1 522 ? -10.999  -15.741 81.749  1.00 57.73  ? 582 ILE B CB  1 
ATOM   8293  C CG1 . ILE B 1 522 ? -12.231  -16.548 81.346  1.00 61.93  ? 582 ILE B CG1 1 
ATOM   8294  C CG2 . ILE B 1 522 ? -10.479  -16.168 83.106  1.00 61.36  ? 582 ILE B CG2 1 
ATOM   8295  C CD1 . ILE B 1 522 ? -12.048  -18.025 81.500  1.00 60.00  ? 582 ILE B CD1 1 
ATOM   8296  N N   . PHE B 1 523 ? -13.029  -13.431 80.201  1.00 57.85  ? 583 PHE B N   1 
ATOM   8297  C CA  . PHE B 1 523 ? -13.594  -12.990 78.902  1.00 53.81  ? 583 PHE B CA  1 
ATOM   8298  C C   . PHE B 1 523 ? -14.238  -11.625 79.024  1.00 55.14  ? 583 PHE B C   1 
ATOM   8299  O O   . PHE B 1 523 ? -14.717  -11.245 80.081  1.00 61.00  ? 583 PHE B O   1 
ATOM   8300  C CB  . PHE B 1 523 ? -14.660  -13.958 78.444  1.00 52.38  ? 583 PHE B CB  1 
ATOM   8301  C CG  . PHE B 1 523 ? -14.153  -15.357 78.263  1.00 57.01  ? 583 PHE B CG  1 
ATOM   8302  C CD1 . PHE B 1 523 ? -13.142  -15.598 77.361  1.00 62.79  ? 583 PHE B CD1 1 
ATOM   8303  C CD2 . PHE B 1 523 ? -14.716  -16.421 78.945  1.00 60.34  ? 583 PHE B CD2 1 
ATOM   8304  C CE1 . PHE B 1 523 ? -12.712  -16.890 77.130  1.00 74.12  ? 583 PHE B CE1 1 
ATOM   8305  C CE2 . PHE B 1 523 ? -14.254  -17.706 78.742  1.00 60.74  ? 583 PHE B CE2 1 
ATOM   8306  C CZ  . PHE B 1 523 ? -13.266  -17.943 77.825  1.00 70.96  ? 583 PHE B CZ  1 
ATOM   8307  N N   . PRO B 1 524 ? -14.324  -10.859 77.930  1.00 62.16  ? 584 PRO B N   1 
ATOM   8308  C CA  . PRO B 1 524 ? -15.024  -9.582  77.981  1.00 71.70  ? 584 PRO B CA  1 
ATOM   8309  C C   . PRO B 1 524 ? -16.523  -9.869  78.000  1.00 79.11  ? 584 PRO B C   1 
ATOM   8310  O O   . PRO B 1 524 ? -16.962  -10.974 77.647  1.00 61.92  ? 584 PRO B O   1 
ATOM   8311  C CB  . PRO B 1 524 ? -14.565  -8.838  76.720  1.00 72.81  ? 584 PRO B CB  1 
ATOM   8312  C CG  . PRO B 1 524 ? -14.069  -9.943  75.766  1.00 67.05  ? 584 PRO B CG  1 
ATOM   8313  C CD  . PRO B 1 524 ? -13.772  -11.176 76.606  1.00 64.23  ? 584 PRO B CD  1 
ATOM   8314  N N   . PRO B 1 525 ? -17.355  -8.880  78.400  1.00 77.53  ? 585 PRO B N   1 
ATOM   8315  C CA  . PRO B 1 525 ? -18.791  -9.108  78.525  1.00 73.41  ? 585 PRO B CA  1 
ATOM   8316  C C   . PRO B 1 525 ? -19.382  -9.418  77.139  1.00 69.49  ? 585 PRO B C   1 
ATOM   8317  O O   . PRO B 1 525 ? -18.760  -9.075  76.162  1.00 66.81  ? 585 PRO B O   1 
ATOM   8318  C CB  . PRO B 1 525 ? -19.307  -7.791  79.137  1.00 74.29  ? 585 PRO B CB  1 
ATOM   8319  C CG  . PRO B 1 525 ? -18.279  -6.756  78.742  1.00 71.21  ? 585 PRO B CG  1 
ATOM   8320  C CD  . PRO B 1 525 ? -16.962  -7.498  78.703  1.00 78.82  ? 585 PRO B CD  1 
ATOM   8321  N N   . PHE B 1 526 ? -20.557  -10.065 77.067  1.00 66.97  ? 586 PHE B N   1 
ATOM   8322  C CA  . PHE B 1 526 ? -21.229  -10.430 75.794  1.00 54.35  ? 586 PHE B CA  1 
ATOM   8323  C C   . PHE B 1 526 ? -21.673  -9.174  75.050  1.00 49.26  ? 586 PHE B C   1 
ATOM   8324  O O   . PHE B 1 526 ? -21.917  -9.286  73.847  1.00 50.33  ? 586 PHE B O   1 
ATOM   8325  C CB  . PHE B 1 526 ? -22.440  -11.321 76.061  1.00 54.22  ? 586 PHE B CB  1 
ATOM   8326  C CG  . PHE B 1 526 ? -22.132  -12.779 75.994  1.00 54.57  ? 586 PHE B CG  1 
ATOM   8327  C CD1 . PHE B 1 526 ? -21.641  -13.336 74.835  1.00 56.91  ? 586 PHE B CD1 1 
ATOM   8328  C CD2 . PHE B 1 526 ? -22.352  -13.599 77.080  1.00 64.56  ? 586 PHE B CD2 1 
ATOM   8329  C CE1 . PHE B 1 526 ? -21.386  -14.696 74.765  1.00 59.90  ? 586 PHE B CE1 1 
ATOM   8330  C CE2 . PHE B 1 526 ? -22.101  -14.962 77.010  1.00 61.05  ? 586 PHE B CE2 1 
ATOM   8331  C CZ  . PHE B 1 526 ? -21.610  -15.505 75.854  1.00 60.39  ? 586 PHE B CZ  1 
ATOM   8332  N N   . THR B 1 527 ? -21.779  -8.045  75.744  1.00 47.68  ? 587 THR B N   1 
ATOM   8333  C CA  . THR B 1 527 ? -22.023  -6.697  75.174  1.00 54.40  ? 587 THR B CA  1 
ATOM   8334  C C   . THR B 1 527 ? -20.994  -6.322  74.093  1.00 57.44  ? 587 THR B C   1 
ATOM   8335  O O   . THR B 1 527 ? -21.155  -5.248  73.522  1.00 64.87  ? 587 THR B O   1 
ATOM   8336  C CB  . THR B 1 527 ? -21.970  -5.641  76.283  1.00 61.48  ? 587 THR B CB  1 
ATOM   8337  O OG1 . THR B 1 527 ? -20.649  -5.534  76.805  1.00 63.85  ? 587 THR B OG1 1 
ATOM   8338  C CG2 . THR B 1 527 ? -22.833  -5.974  77.478  1.00 71.17  ? 587 THR B CG2 1 
ATOM   8339  N N   . SER B 1 528 ? -19.948  -7.130  73.854  1.00 65.17  ? 588 SER B N   1 
ATOM   8340  C CA  . SER B 1 528 ? -18.850  -6.859  72.877  1.00 67.75  ? 588 SER B CA  1 
ATOM   8341  C C   . SER B 1 528 ? -18.730  -7.998  71.846  1.00 64.39  ? 588 SER B C   1 
ATOM   8342  O O   . SER B 1 528 ? -17.760  -7.964  71.043  1.00 63.57  ? 588 SER B O   1 
ATOM   8343  C CB  . SER B 1 528 ? -17.524  -6.682  73.596  1.00 67.28  ? 588 SER B CB  1 
ATOM   8344  O OG  . SER B 1 528 ? -17.647  -5.830  74.725  1.00 68.92  ? 588 SER B OG  1 
ATOM   8345  N N   . ILE B 1 529 ? -19.649  -8.972  71.862  1.00 54.36  ? 589 ILE B N   1 
ATOM   8346  C CA  . ILE B 1 529 ? -19.563  -10.244 71.084  1.00 53.52  ? 589 ILE B CA  1 
ATOM   8347  C C   . ILE B 1 529 ? -19.524  -9.932  69.578  1.00 61.49  ? 589 ILE B C   1 
ATOM   8348  O O   . ILE B 1 529 ? -19.066  -10.795 68.777  1.00 64.89  ? 589 ILE B O   1 
ATOM   8349  C CB  . ILE B 1 529 ? -20.715  -11.196 71.462  1.00 54.79  ? 589 ILE B CB  1 
ATOM   8350  C CG1 . ILE B 1 529 ? -20.504  -12.624 70.930  1.00 57.06  ? 589 ILE B CG1 1 
ATOM   8351  C CG2 . ILE B 1 529 ? -22.055  -10.621 71.013  1.00 52.34  ? 589 ILE B CG2 1 
ATOM   8352  C CD1 . ILE B 1 529 ? -19.296  -13.371 71.451  1.00 48.58  ? 589 ILE B CD1 1 
ATOM   8353  N N   . ARG B 1 530 ? -19.988  -8.750  69.165  1.00 68.33  ? 590 ARG B N   1 
ATOM   8354  C CA  . ARG B 1 530 ? -19.875  -8.373  67.737  1.00 68.21  ? 590 ARG B CA  1 
ATOM   8355  C C   . ARG B 1 530 ? -18.417  -8.061  67.420  1.00 70.82  ? 590 ARG B C   1 
ATOM   8356  O O   . ARG B 1 530 ? -17.905  -8.662  66.427  1.00 65.55  ? 590 ARG B O   1 
ATOM   8357  C CB  . ARG B 1 530 ? -20.916  -7.338  67.338  1.00 80.84  ? 590 ARG B CB  1 
ATOM   8358  C CG  . ARG B 1 530 ? -21.923  -7.985  66.401  1.00 80.35  ? 590 ARG B CG  1 
ATOM   8359  C CD  . ARG B 1 530 ? -22.911  -7.000  65.842  1.00 87.02  ? 590 ARG B CD  1 
ATOM   8360  N NE  . ARG B 1 530 ? -23.699  -7.562  64.758  1.00 88.94  ? 590 ARG B NE  1 
ATOM   8361  C CZ  . ARG B 1 530 ? -24.540  -8.584  64.866  1.00 68.97  ? 590 ARG B CZ  1 
ATOM   8362  N NH1 . ARG B 1 530 ? -24.683  -9.206  66.022  1.00 64.04  ? 590 ARG B NH1 1 
ATOM   8363  N NH2 . ARG B 1 530 ? -25.242  -8.966  63.815  1.00 59.08  ? 590 ARG B NH2 1 
ATOM   8364  N N   . LYS B 1 531 ? -17.740  -7.263  68.253  1.00 71.04  ? 591 LYS B N   1 
ATOM   8365  C CA  . LYS B 1 531 ? -16.270  -7.042  68.113  1.00 71.13  ? 591 LYS B CA  1 
ATOM   8366  C C   . LYS B 1 531 ? -15.558  -8.413  68.149  1.00 55.68  ? 591 LYS B C   1 
ATOM   8367  O O   . LYS B 1 531 ? -14.792  -8.693  67.201  1.00 44.22  ? 591 LYS B O   1 
ATOM   8368  C CB  . LYS B 1 531 ? -15.684  -6.067  69.146  1.00 83.56  ? 591 LYS B CB  1 
ATOM   8369  C CG  . LYS B 1 531 ? -16.640  -5.313  70.080  1.00 114.83 ? 591 LYS B CG  1 
ATOM   8370  C CD  . LYS B 1 531 ? -16.007  -4.039  70.709  1.00 122.63 ? 591 LYS B CD  1 
ATOM   8371  C CE  . LYS B 1 531 ? -16.328  -3.713  72.171  1.00 109.17 ? 591 LYS B CE  1 
ATOM   8372  N NZ  . LYS B 1 531 ? -15.163  -3.932  73.081  1.00 98.73  ? 591 LYS B NZ  1 
ATOM   8373  N N   . ILE B 1 532 ? -15.813  -9.257  69.165  1.00 51.58  ? 592 ILE B N   1 
ATOM   8374  C CA  . ILE B 1 532 ? -15.129  -10.582 69.352  1.00 51.45  ? 592 ILE B CA  1 
ATOM   8375  C C   . ILE B 1 532 ? -15.226  -11.443 68.089  1.00 50.48  ? 592 ILE B C   1 
ATOM   8376  O O   . ILE B 1 532 ? -14.215  -12.069 67.715  1.00 49.51  ? 592 ILE B O   1 
ATOM   8377  C CB  . ILE B 1 532 ? -15.749  -11.421 70.484  1.00 51.49  ? 592 ILE B CB  1 
ATOM   8378  C CG1 . ILE B 1 532 ? -15.775  -10.779 71.875  1.00 54.44  ? 592 ILE B CG1 1 
ATOM   8379  C CG2 . ILE B 1 532 ? -15.116  -12.791 70.495  1.00 47.51  ? 592 ILE B CG2 1 
ATOM   8380  C CD1 . ILE B 1 532 ? -14.660  -9.853  72.143  1.00 64.10  ? 592 ILE B CD1 1 
ATOM   8381  N N   . SER B 1 533 ? -16.433  -11.555 67.526  1.00 57.67  ? 593 SER B N   1 
ATOM   8382  C CA  . SER B 1 533 ? -16.751  -12.498 66.422  1.00 57.47  ? 593 SER B CA  1 
ATOM   8383  C C   . SER B 1 533 ? -16.002  -12.061 65.161  1.00 55.19  ? 593 SER B C   1 
ATOM   8384  O O   . SER B 1 533 ? -15.458  -12.971 64.470  1.00 52.29  ? 593 SER B O   1 
ATOM   8385  C CB  . SER B 1 533 ? -18.237  -12.638 66.223  1.00 56.61  ? 593 SER B CB  1 
ATOM   8386  O OG  . SER B 1 533 ? -18.773  -13.616 67.110  1.00 56.68  ? 593 SER B OG  1 
ATOM   8387  N N   . ALA B 1 534 ? -15.930  -10.741 64.898  1.00 55.48  ? 594 ALA B N   1 
ATOM   8388  C CA  . ALA B 1 534 ? -15.212  -10.154 63.725  1.00 57.19  ? 594 ALA B CA  1 
ATOM   8389  C C   . ALA B 1 534 ? -13.725  -10.516 63.805  1.00 55.65  ? 594 ALA B C   1 
ATOM   8390  O O   . ALA B 1 534 ? -13.172  -11.007 62.806  1.00 47.69  ? 594 ALA B O   1 
ATOM   8391  C CB  . ALA B 1 534 ? -15.376  -8.655  63.642  1.00 57.98  ? 594 ALA B CB  1 
ATOM   8392  N N   . HIS B 1 535 ? -13.102  -10.298 64.964  1.00 55.18  ? 595 HIS B N   1 
ATOM   8393  C CA  . HIS B 1 535 ? -11.676  -10.611 65.195  1.00 49.27  ? 595 HIS B CA  1 
ATOM   8394  C C   . HIS B 1 535 ? -11.473  -12.125 65.127  1.00 46.62  ? 595 HIS B C   1 
ATOM   8395  O O   . HIS B 1 535 ? -10.471  -12.521 64.551  1.00 58.10  ? 595 HIS B O   1 
ATOM   8396  C CB  . HIS B 1 535 ? -11.179  -9.986  66.492  1.00 52.42  ? 595 HIS B CB  1 
ATOM   8397  C CG  . HIS B 1 535 ? -10.991  -8.510  66.415  1.00 49.78  ? 595 HIS B CG  1 
ATOM   8398  N ND1 . HIS B 1 535 ? -9.918   -7.926  65.815  1.00 54.93  ? 595 HIS B ND1 1 
ATOM   8399  C CD2 . HIS B 1 535 ? -11.749  -7.500  66.895  1.00 53.03  ? 595 HIS B CD2 1 
ATOM   8400  C CE1 . HIS B 1 535 ? -10.012  -6.605  65.933  1.00 60.01  ? 595 HIS B CE1 1 
ATOM   8401  N NE2 . HIS B 1 535 ? -11.126  -6.316  66.608  1.00 54.11  ? 595 HIS B NE2 1 
ATOM   8402  N N   . ILE B 1 536 ? -12.378  -12.952 65.646  1.00 46.44  ? 596 ILE B N   1 
ATOM   8403  C CA  . ILE B 1 536 ? -12.227  -14.434 65.525  1.00 44.60  ? 596 ILE B CA  1 
ATOM   8404  C C   . ILE B 1 536 ? -12.383  -14.795 64.044  1.00 48.96  ? 596 ILE B C   1 
ATOM   8405  O O   . ILE B 1 536 ? -11.620  -15.637 63.547  1.00 54.26  ? 596 ILE B O   1 
ATOM   8406  C CB  . ILE B 1 536 ? -13.230  -15.193 66.409  1.00 41.84  ? 596 ILE B CB  1 
ATOM   8407  C CG1 . ILE B 1 536 ? -12.967  -14.948 67.886  1.00 41.24  ? 596 ILE B CG1 1 
ATOM   8408  C CG2 . ILE B 1 536 ? -13.236  -16.683 66.085  1.00 44.60  ? 596 ILE B CG2 1 
ATOM   8409  C CD1 . ILE B 1 536 ? -14.035  -15.507 68.783  1.00 48.19  ? 596 ILE B CD1 1 
ATOM   8410  N N   . ALA B 1 537 ? -13.351  -14.203 63.356  1.00 45.37  ? 597 ALA B N   1 
ATOM   8411  C CA  . ALA B 1 537 ? -13.599  -14.507 61.933  1.00 50.24  ? 597 ALA B CA  1 
ATOM   8412  C C   . ALA B 1 537 ? -12.326  -14.201 61.125  1.00 66.25  ? 597 ALA B C   1 
ATOM   8413  O O   . ALA B 1 537 ? -11.849  -15.114 60.400  1.00 62.77  ? 597 ALA B O   1 
ATOM   8414  C CB  . ALA B 1 537 ? -14.795  -13.718 61.460  1.00 53.34  ? 597 ALA B CB  1 
ATOM   8415  N N   . ALA B 1 538 ? -11.777  -12.975 61.272  1.00 74.50  ? 598 ALA B N   1 
ATOM   8416  C CA  . ALA B 1 538 ? -10.581  -12.473 60.547  1.00 61.52  ? 598 ALA B CA  1 
ATOM   8417  C C   . ALA B 1 538 ? -9.426   -13.453 60.769  1.00 59.72  ? 598 ALA B C   1 
ATOM   8418  O O   . ALA B 1 538 ? -8.770   -13.804 59.774  1.00 64.60  ? 598 ALA B O   1 
ATOM   8419  C CB  . ALA B 1 538 ? -10.214  -11.074 60.977  1.00 56.86  ? 598 ALA B CB  1 
ATOM   8420  N N   . ALA B 1 539 ? -9.221   -13.915 62.007  1.00 48.68  ? 599 ALA B N   1 
ATOM   8421  C CA  . ALA B 1 539 ? -8.172   -14.895 62.366  1.00 52.10  ? 599 ALA B CA  1 
ATOM   8422  C C   . ALA B 1 539 ? -8.429   -16.247 61.697  1.00 58.30  ? 599 ALA B C   1 
ATOM   8423  O O   . ALA B 1 539 ? -7.465   -16.796 61.128  1.00 78.39  ? 599 ALA B O   1 
ATOM   8424  C CB  . ALA B 1 539 ? -8.094   -15.075 63.855  1.00 57.61  ? 599 ALA B CB  1 
ATOM   8425  N N   . VAL B 1 540 ? -9.646   -16.797 61.789  1.00 54.52  ? 600 VAL B N   1 
ATOM   8426  C CA  . VAL B 1 540 ? -9.963   -18.165 61.266  1.00 60.90  ? 600 VAL B CA  1 
ATOM   8427  C C   . VAL B 1 540 ? -9.890   -18.163 59.734  1.00 59.51  ? 600 VAL B C   1 
ATOM   8428  O O   . VAL B 1 540 ? -9.615   -19.240 59.145  1.00 58.54  ? 600 VAL B O   1 
ATOM   8429  C CB  . VAL B 1 540 ? -11.331  -18.681 61.740  1.00 54.44  ? 600 VAL B CB  1 
ATOM   8430  C CG1 . VAL B 1 540 ? -11.699  -19.969 61.003  1.00 55.26  ? 600 VAL B CG1 1 
ATOM   8431  C CG2 . VAL B 1 540 ? -11.352  -18.892 63.247  1.00 58.72  ? 600 VAL B CG2 1 
ATOM   8432  N N   . ALA B 1 541 ? -10.173  -17.009 59.130  1.00 56.79  ? 601 ALA B N   1 
ATOM   8433  C CA  . ALA B 1 541 ? -10.113  -16.778 57.669  1.00 61.67  ? 601 ALA B CA  1 
ATOM   8434  C C   . ALA B 1 541 ? -8.642   -16.712 57.252  1.00 64.48  ? 601 ALA B C   1 
ATOM   8435  O O   . ALA B 1 541 ? -8.252   -17.431 56.300  1.00 65.65  ? 601 ALA B O   1 
ATOM   8436  C CB  . ALA B 1 541 ? -10.852  -15.513 57.305  1.00 62.73  ? 601 ALA B CB  1 
ATOM   8437  N N   . ALA B 1 542 ? -7.855   -15.890 57.957  1.00 62.94  ? 602 ALA B N   1 
ATOM   8438  C CA  . ALA B 1 542 ? -6.401   -15.710 57.740  1.00 52.97  ? 602 ALA B CA  1 
ATOM   8439  C C   . ALA B 1 542 ? -5.728   -17.084 57.760  1.00 49.97  ? 602 ALA B C   1 
ATOM   8440  O O   . ALA B 1 542 ? -4.977   -17.368 56.818  1.00 56.41  ? 602 ALA B O   1 
ATOM   8441  C CB  . ALA B 1 542 ? -5.830   -14.772 58.768  1.00 50.92  ? 602 ALA B CB  1 
ATOM   8442  N N   . LYS B 1 543 ? -6.058   -17.920 58.748  1.00 52.59  ? 603 LYS B N   1 
ATOM   8443  C CA  . LYS B 1 543 ? -5.509   -19.294 58.897  1.00 62.59  ? 603 LYS B CA  1 
ATOM   8444  C C   . LYS B 1 543 ? -5.975   -20.159 57.726  1.00 60.74  ? 603 LYS B C   1 
ATOM   8445  O O   . LYS B 1 543 ? -5.214   -21.024 57.309  1.00 60.93  ? 603 LYS B O   1 
ATOM   8446  C CB  . LYS B 1 543 ? -5.961   -19.962 60.198  1.00 70.77  ? 603 LYS B CB  1 
ATOM   8447  C CG  . LYS B 1 543 ? -5.341   -21.334 60.486  1.00 73.63  ? 603 LYS B CG  1 
ATOM   8448  C CD  . LYS B 1 543 ? -3.826   -21.317 60.620  1.00 68.72  ? 603 LYS B CD  1 
ATOM   8449  C CE  . LYS B 1 543 ? -3.344   -20.619 61.872  1.00 71.36  ? 603 LYS B CE  1 
ATOM   8450  N NZ  . LYS B 1 543 ? -2.045   -19.944 61.618  1.00 73.61  ? 603 LYS B NZ  1 
ATOM   8451  N N   . ALA B 1 544 ? -7.191   -19.939 57.240  1.00 65.72  ? 604 ALA B N   1 
ATOM   8452  C CA  . ALA B 1 544 ? -7.792   -20.718 56.136  1.00 70.84  ? 604 ALA B CA  1 
ATOM   8453  C C   . ALA B 1 544 ? -6.985   -20.462 54.862  1.00 67.64  ? 604 ALA B C   1 
ATOM   8454  O O   . ALA B 1 544 ? -6.635   -21.478 54.196  1.00 62.12  ? 604 ALA B O   1 
ATOM   8455  C CB  . ALA B 1 544 ? -9.257   -20.380 55.989  1.00 68.48  ? 604 ALA B CB  1 
ATOM   8456  N N   . TYR B 1 545 ? -6.684   -19.178 54.586  1.00 60.76  ? 605 TYR B N   1 
ATOM   8457  C CA  . TYR B 1 545 ? -5.859   -18.697 53.445  1.00 59.58  ? 605 TYR B CA  1 
ATOM   8458  C C   . TYR B 1 545 ? -4.432   -19.247 53.576  1.00 57.39  ? 605 TYR B C   1 
ATOM   8459  O O   . TYR B 1 545 ? -3.977   -19.933 52.661  1.00 53.13  ? 605 TYR B O   1 
ATOM   8460  C CB  . TYR B 1 545 ? -5.854   -17.168 53.372  1.00 54.88  ? 605 TYR B CB  1 
ATOM   8461  C CG  . TYR B 1 545 ? -7.137   -16.556 52.867  1.00 56.19  ? 605 TYR B CG  1 
ATOM   8462  C CD1 . TYR B 1 545 ? -7.675   -16.909 51.640  1.00 58.29  ? 605 TYR B CD1 1 
ATOM   8463  C CD2 . TYR B 1 545 ? -7.817   -15.601 53.604  1.00 66.94  ? 605 TYR B CD2 1 
ATOM   8464  C CE1 . TYR B 1 545 ? -8.847   -16.341 51.153  1.00 59.02  ? 605 TYR B CE1 1 
ATOM   8465  C CE2 . TYR B 1 545 ? -8.994   -15.027 53.144  1.00 68.64  ? 605 TYR B CE2 1 
ATOM   8466  C CZ  . TYR B 1 545 ? -9.515   -15.392 51.913  1.00 65.07  ? 605 TYR B CZ  1 
ATOM   8467  O OH  . TYR B 1 545 ? -10.667  -14.791 51.488  1.00 59.06  ? 605 TYR B OH  1 
ATOM   8468  N N   . GLU B 1 546 ? -3.759   -18.947 54.689  1.00 56.53  ? 606 GLU B N   1 
ATOM   8469  C CA  . GLU B 1 546 ? -2.413   -19.465 55.034  1.00 61.13  ? 606 GLU B CA  1 
ATOM   8470  C C   . GLU B 1 546 ? -2.363   -20.973 54.744  1.00 58.51  ? 606 GLU B C   1 
ATOM   8471  O O   . GLU B 1 546 ? -1.565   -21.377 53.913  1.00 71.58  ? 606 GLU B O   1 
ATOM   8472  C CB  . GLU B 1 546 ? -2.118   -19.123 56.496  1.00 74.99  ? 606 GLU B CB  1 
ATOM   8473  C CG  . GLU B 1 546 ? -0.672   -19.291 56.933  1.00 90.65  ? 606 GLU B CG  1 
ATOM   8474  C CD  . GLU B 1 546 ? -0.463   -19.411 58.445  1.00 93.25  ? 606 GLU B CD  1 
ATOM   8475  O OE1 . GLU B 1 546 ? -1.239   -18.778 59.207  1.00 100.65 ? 606 GLU B OE1 1 
ATOM   8476  O OE2 . GLU B 1 546 ? 0.490    -20.134 58.859  1.00 78.80  ? 606 GLU B OE2 1 
ATOM   8477  N N   . LEU B 1 547 ? -3.222   -21.788 55.343  1.00 56.71  ? 607 LEU B N   1 
ATOM   8478  C CA  . LEU B 1 547 ? -3.248   -23.258 55.098  1.00 58.43  ? 607 LEU B CA  1 
ATOM   8479  C C   . LEU B 1 547 ? -3.709   -23.594 53.673  1.00 58.06  ? 607 LEU B C   1 
ATOM   8480  O O   . LEU B 1 547 ? -3.759   -24.807 53.349  1.00 56.22  ? 607 LEU B O   1 
ATOM   8481  C CB  . LEU B 1 547 ? -4.216   -23.921 56.072  1.00 60.93  ? 607 LEU B CB  1 
ATOM   8482  C CG  . LEU B 1 547 ? -3.772   -24.011 57.525  1.00 68.70  ? 607 LEU B CG  1 
ATOM   8483  C CD1 . LEU B 1 547 ? -4.952   -24.470 58.380  1.00 66.33  ? 607 LEU B CD1 1 
ATOM   8484  C CD2 . LEU B 1 547 ? -2.566   -24.921 57.686  1.00 68.12  ? 607 LEU B CD2 1 
ATOM   8485  N N   . GLY B 1 548 ? -4.085   -22.596 52.870  1.00 56.75  ? 608 GLY B N   1 
ATOM   8486  C CA  . GLY B 1 548 ? -4.663   -22.793 51.526  1.00 60.69  ? 608 GLY B CA  1 
ATOM   8487  C C   . GLY B 1 548 ? -5.830   -23.783 51.539  1.00 69.60  ? 608 GLY B C   1 
ATOM   8488  O O   . GLY B 1 548 ? -5.782   -24.769 50.783  1.00 69.01  ? 608 GLY B O   1 
ATOM   8489  N N   . LEU B 1 549 ? -6.843   -23.535 52.381  1.00 79.55  ? 609 LEU B N   1 
ATOM   8490  C CA  . LEU B 1 549 ? -8.175   -24.197 52.304  1.00 65.35  ? 609 LEU B CA  1 
ATOM   8491  C C   . LEU B 1 549 ? -9.265   -23.199 51.889  1.00 63.29  ? 609 LEU B C   1 
ATOM   8492  O O   . LEU B 1 549 ? -10.382  -23.675 51.668  1.00 65.44  ? 609 LEU B O   1 
ATOM   8493  C CB  . LEU B 1 549 ? -8.509   -24.807 53.660  1.00 66.78  ? 609 LEU B CB  1 
ATOM   8494  C CG  . LEU B 1 549 ? -7.726   -26.037 54.079  1.00 63.90  ? 609 LEU B CG  1 
ATOM   8495  C CD1 . LEU B 1 549 ? -7.350   -26.942 52.918  1.00 63.19  ? 609 LEU B CD1 1 
ATOM   8496  C CD2 . LEU B 1 549 ? -6.534   -25.597 54.865  1.00 66.48  ? 609 LEU B CD2 1 
ATOM   8497  N N   . ALA B 1 550 ? -8.953   -21.898 51.785  1.00 62.48  ? 610 ALA B N   1 
ATOM   8498  C CA  . ALA B 1 550 ? -9.907   -20.826 51.404  1.00 64.35  ? 610 ALA B CA  1 
ATOM   8499  C C   . ALA B 1 550 ? -10.121  -20.854 49.891  1.00 67.76  ? 610 ALA B C   1 
ATOM   8500  O O   . ALA B 1 550 ? -9.187   -21.303 49.202  1.00 77.90  ? 610 ALA B O   1 
ATOM   8501  C CB  . ALA B 1 550 ? -9.383   -19.490 51.836  1.00 63.89  ? 610 ALA B CB  1 
ATOM   8502  N N   . THR B 1 551 ? -11.301  -20.424 49.412  1.00 68.16  ? 611 THR B N   1 
ATOM   8503  C CA  . THR B 1 551 ? -11.664  -20.332 47.966  1.00 63.33  ? 611 THR B CA  1 
ATOM   8504  C C   . THR B 1 551 ? -12.183  -18.938 47.609  1.00 54.61  ? 611 THR B C   1 
ATOM   8505  O O   . THR B 1 551 ? -12.487  -18.764 46.448  1.00 56.03  ? 611 THR B O   1 
ATOM   8506  C CB  . THR B 1 551 ? -12.726  -21.359 47.527  1.00 56.83  ? 611 THR B CB  1 
ATOM   8507  O OG1 . THR B 1 551 ? -13.992  -20.933 48.032  1.00 65.81  ? 611 THR B OG1 1 
ATOM   8508  C CG2 . THR B 1 551 ? -12.428  -22.775 47.968  1.00 49.88  ? 611 THR B CG2 1 
ATOM   8509  N N   . ARG B 1 552 ? -12.323  -18.004 48.549  1.00 58.11  ? 612 ARG B N   1 
ATOM   8510  C CA  . ARG B 1 552 ? -12.681  -16.594 48.209  1.00 67.63  ? 612 ARG B CA  1 
ATOM   8511  C C   . ARG B 1 552 ? -11.380  -15.832 47.965  1.00 72.24  ? 612 ARG B C   1 
ATOM   8512  O O   . ARG B 1 552 ? -10.936  -15.132 48.884  1.00 77.50  ? 612 ARG B O   1 
ATOM   8513  C CB  . ARG B 1 552 ? -13.530  -15.908 49.280  1.00 68.84  ? 612 ARG B CB  1 
ATOM   8514  C CG  . ARG B 1 552 ? -15.015  -15.880 48.927  1.00 79.17  ? 612 ARG B CG  1 
ATOM   8515  C CD  . ARG B 1 552 ? -15.925  -15.041 49.817  1.00 93.75  ? 612 ARG B CD  1 
ATOM   8516  N NE  . ARG B 1 552 ? -17.197  -15.721 50.053  1.00 91.83  ? 612 ARG B NE  1 
ATOM   8517  C CZ  . ARG B 1 552 ? -18.229  -15.734 49.224  1.00 97.31  ? 612 ARG B CZ  1 
ATOM   8518  N NH1 . ARG B 1 552 ? -18.180  -15.065 48.083  1.00 98.44  ? 612 ARG B NH1 1 
ATOM   8519  N NH2 . ARG B 1 552 ? -19.314  -16.424 49.543  1.00 99.45  ? 612 ARG B NH2 1 
ATOM   8520  N N   . LEU B 1 553 ? -10.764  -16.037 46.789  1.00 72.00  ? 613 LEU B N   1 
ATOM   8521  C CA  . LEU B 1 553 ? -9.444   -15.458 46.417  1.00 73.48  ? 613 LEU B CA  1 
ATOM   8522  C C   . LEU B 1 553 ? -9.695   -14.221 45.562  1.00 78.03  ? 613 LEU B C   1 
ATOM   8523  O O   . LEU B 1 553 ? -10.686  -14.175 44.845  1.00 77.46  ? 613 LEU B O   1 
ATOM   8524  C CB  . LEU B 1 553 ? -8.607   -16.532 45.709  1.00 68.31  ? 613 LEU B CB  1 
ATOM   8525  C CG  . LEU B 1 553 ? -8.403   -17.826 46.523  1.00 64.89  ? 613 LEU B CG  1 
ATOM   8526  C CD1 . LEU B 1 553 ? -7.981   -18.992 45.657  1.00 68.78  ? 613 LEU B CD1 1 
ATOM   8527  C CD2 . LEU B 1 553 ? -7.386   -17.641 47.636  1.00 63.40  ? 613 LEU B CD2 1 
ATOM   8528  N N   . PRO B 1 554 ? -8.874   -13.145 45.647  1.00 82.13  ? 614 PRO B N   1 
ATOM   8529  C CA  . PRO B 1 554 ? -7.794   -13.037 46.632  1.00 83.72  ? 614 PRO B CA  1 
ATOM   8530  C C   . PRO B 1 554 ? -8.358   -12.674 48.008  1.00 85.03  ? 614 PRO B C   1 
ATOM   8531  O O   . PRO B 1 554 ? -9.486   -12.185 48.086  1.00 85.94  ? 614 PRO B O   1 
ATOM   8532  C CB  . PRO B 1 554 ? -6.893   -11.906 46.100  1.00 81.36  ? 614 PRO B CB  1 
ATOM   8533  C CG  . PRO B 1 554 ? -7.601   -11.320 44.873  1.00 81.67  ? 614 PRO B CG  1 
ATOM   8534  C CD  . PRO B 1 554 ? -8.981   -11.946 44.801  1.00 77.83  ? 614 PRO B CD  1 
ATOM   8535  N N   . PRO B 1 555 ? -7.609   -12.891 49.120  1.00 75.87  ? 615 PRO B N   1 
ATOM   8536  C CA  . PRO B 1 555 ? -8.052   -12.463 50.445  1.00 69.25  ? 615 PRO B CA  1 
ATOM   8537  C C   . PRO B 1 555 ? -8.146   -10.942 50.492  1.00 68.48  ? 615 PRO B C   1 
ATOM   8538  O O   . PRO B 1 555 ? -7.365   -10.241 49.865  1.00 64.42  ? 615 PRO B O   1 
ATOM   8539  C CB  . PRO B 1 555 ? -6.972   -12.955 51.423  1.00 62.94  ? 615 PRO B CB  1 
ATOM   8540  C CG  . PRO B 1 555 ? -5.767   -13.258 50.564  1.00 64.65  ? 615 PRO B CG  1 
ATOM   8541  C CD  . PRO B 1 555 ? -6.290   -13.540 49.166  1.00 72.17  ? 615 PRO B CD  1 
ATOM   8542  N N   . PRO B 1 556 ? -9.145   -10.373 51.183  1.00 72.03  ? 616 PRO B N   1 
ATOM   8543  C CA  . PRO B 1 556 ? -9.227   -8.914  51.302  1.00 69.99  ? 616 PRO B CA  1 
ATOM   8544  C C   . PRO B 1 556 ? -8.013   -8.388  52.067  1.00 67.07  ? 616 PRO B C   1 
ATOM   8545  O O   . PRO B 1 556 ? -7.408   -9.178  52.755  1.00 63.59  ? 616 PRO B O   1 
ATOM   8546  C CB  . PRO B 1 556 ? -10.510  -8.656  52.084  1.00 71.30  ? 616 PRO B CB  1 
ATOM   8547  C CG  . PRO B 1 556 ? -11.283  -9.981  51.933  1.00 81.70  ? 616 PRO B CG  1 
ATOM   8548  C CD  . PRO B 1 556 ? -10.264  -11.100 51.804  1.00 68.23  ? 616 PRO B CD  1 
ATOM   8549  N N   . SER B 1 557 ? -7.677   -7.105  51.907  1.00 75.65  ? 617 SER B N   1 
ATOM   8550  C CA  . SER B 1 557 ? -6.502   -6.492  52.596  1.00 78.75  ? 617 SER B CA  1 
ATOM   8551  C C   . SER B 1 557 ? -6.731   -6.548  54.114  1.00 73.81  ? 617 SER B C   1 
ATOM   8552  O O   . SER B 1 557 ? -5.878   -7.090  54.794  1.00 66.76  ? 617 SER B O   1 
ATOM   8553  C CB  . SER B 1 557 ? -6.191   -5.099  52.101  1.00 82.34  ? 617 SER B CB  1 
ATOM   8554  O OG  . SER B 1 557 ? -6.561   -4.101  53.043  1.00 88.05  ? 617 SER B OG  1 
ATOM   8555  N N   . ASP B 1 558 ? -7.895   -6.071  54.579  1.00 85.68  ? 618 ASP B N   1 
ATOM   8556  C CA  . ASP B 1 558 ? -8.304   -5.885  56.006  1.00 73.81  ? 618 ASP B CA  1 
ATOM   8557  C C   . ASP B 1 558 ? -9.399   -6.890  56.400  1.00 62.59  ? 618 ASP B C   1 
ATOM   8558  O O   . ASP B 1 558 ? -10.559  -6.510  56.389  1.00 61.95  ? 618 ASP B O   1 
ATOM   8559  C CB  . ASP B 1 558 ? -8.784   -4.437  56.209  1.00 71.87  ? 618 ASP B CB  1 
ATOM   8560  C CG  . ASP B 1 558 ? -8.992   -4.031  57.661  1.00 71.93  ? 618 ASP B CG  1 
ATOM   8561  O OD1 . ASP B 1 558 ? -9.021   -4.922  58.503  1.00 67.56  ? 618 ASP B OD1 1 
ATOM   8562  O OD2 . ASP B 1 558 ? -9.120   -2.812  57.938  1.00 67.59  ? 618 ASP B OD2 1 
ATOM   8563  N N   . LEU B 1 559 ? -9.030   -8.110  56.787  1.00 62.04  ? 619 LEU B N   1 
ATOM   8564  C CA  . LEU B 1 559 ? -9.963   -9.237  57.060  1.00 63.54  ? 619 LEU B CA  1 
ATOM   8565  C C   . LEU B 1 559 ? -10.940  -8.911  58.200  1.00 68.57  ? 619 LEU B C   1 
ATOM   8566  O O   . LEU B 1 559 ? -12.004  -9.530  58.236  1.00 62.76  ? 619 LEU B O   1 
ATOM   8567  C CB  . LEU B 1 559 ? -9.150   -10.487 57.406  1.00 63.36  ? 619 LEU B CB  1 
ATOM   8568  C CG  . LEU B 1 559 ? -9.184   -11.576 56.344  1.00 65.17  ? 619 LEU B CG  1 
ATOM   8569  C CD1 . LEU B 1 559 ? -8.821   -11.006 54.997  1.00 71.25  ? 619 LEU B CD1 1 
ATOM   8570  C CD2 . LEU B 1 559 ? -8.255   -12.721 56.708  1.00 69.60  ? 619 LEU B CD2 1 
ATOM   8571  N N   . VAL B 1 560 ? -10.598  -8.018  59.125  1.00 74.35  ? 620 VAL B N   1 
ATOM   8572  C CA  . VAL B 1 560 ? -11.522  -7.595  60.221  1.00 74.23  ? 620 VAL B CA  1 
ATOM   8573  C C   . VAL B 1 560 ? -12.637  -6.696  59.651  1.00 80.58  ? 620 VAL B C   1 
ATOM   8574  O O   . VAL B 1 560 ? -13.809  -7.018  59.884  1.00 76.93  ? 620 VAL B O   1 
ATOM   8575  C CB  . VAL B 1 560 ? -10.733  -6.929  61.366  1.00 78.38  ? 620 VAL B CB  1 
ATOM   8576  C CG1 . VAL B 1 560 ? -11.563  -5.973  62.215  1.00 75.14  ? 620 VAL B CG1 1 
ATOM   8577  C CG2 . VAL B 1 560 ? -10.060  -7.985  62.223  1.00 81.73  ? 620 VAL B CG2 1 
ATOM   8578  N N   . LYS B 1 561 ? -12.306  -5.619  58.930  1.00 76.29  ? 621 LYS B N   1 
ATOM   8579  C CA  . LYS B 1 561 ? -13.303  -4.668  58.364  1.00 73.53  ? 621 LYS B CA  1 
ATOM   8580  C C   . LYS B 1 561 ? -14.196  -5.400  57.342  1.00 69.77  ? 621 LYS B C   1 
ATOM   8581  O O   . LYS B 1 561 ? -15.366  -5.044  57.233  1.00 69.71  ? 621 LYS B O   1 
ATOM   8582  C CB  . LYS B 1 561 ? -12.608  -3.426  57.789  1.00 77.21  ? 621 LYS B CB  1 
ATOM   8583  C CG  . LYS B 1 561 ? -13.548  -2.437  57.115  1.00 86.10  ? 621 LYS B CG  1 
ATOM   8584  C CD  . LYS B 1 561 ? -13.231  -0.970  57.202  1.00 94.57  ? 621 LYS B CD  1 
ATOM   8585  C CE  . LYS B 1 561 ? -14.387  -0.144  56.663  1.00 100.51 ? 621 LYS B CE  1 
ATOM   8586  N NZ  . LYS B 1 561 ? -14.427  -0.122  55.175  1.00 106.63 ? 621 LYS B NZ  1 
ATOM   8587  N N   . TYR B 1 562 ? -13.677  -6.402  56.627  1.00 65.66  ? 622 TYR B N   1 
ATOM   8588  C CA  . TYR B 1 562 ? -14.468  -7.227  55.675  1.00 63.05  ? 622 TYR B CA  1 
ATOM   8589  C C   . TYR B 1 562 ? -15.486  -8.058  56.463  1.00 61.88  ? 622 TYR B C   1 
ATOM   8590  O O   . TYR B 1 562 ? -16.676  -8.025  56.124  1.00 61.38  ? 622 TYR B O   1 
ATOM   8591  C CB  . TYR B 1 562 ? -13.567  -8.113  54.807  1.00 65.82  ? 622 TYR B CB  1 
ATOM   8592  C CG  . TYR B 1 562 ? -14.272  -9.102  53.895  1.00 66.60  ? 622 TYR B CG  1 
ATOM   8593  C CD1 . TYR B 1 562 ? -15.048  -8.694  52.805  1.00 57.04  ? 622 TYR B CD1 1 
ATOM   8594  C CD2 . TYR B 1 562 ? -14.141  -10.472 54.117  1.00 67.46  ? 622 TYR B CD2 1 
ATOM   8595  C CE1 . TYR B 1 562 ? -15.665  -9.615  51.969  1.00 56.06  ? 622 TYR B CE1 1 
ATOM   8596  C CE2 . TYR B 1 562 ? -14.732  -11.409 53.281  1.00 64.21  ? 622 TYR B CE2 1 
ATOM   8597  C CZ  . TYR B 1 562 ? -15.507  -10.983 52.208  1.00 66.47  ? 622 TYR B CZ  1 
ATOM   8598  O OH  . TYR B 1 562 ? -16.119  -11.924 51.419  1.00 63.81  ? 622 TYR B OH  1 
ATOM   8599  N N   . ALA B 1 563 ? -15.030  -8.762  57.495  1.00 63.87  ? 623 ALA B N   1 
ATOM   8600  C CA  . ALA B 1 563 ? -15.870  -9.593  58.389  1.00 64.91  ? 623 ALA B CA  1 
ATOM   8601  C C   . ALA B 1 563 ? -16.994  -8.743  58.974  1.00 55.23  ? 623 ALA B C   1 
ATOM   8602  O O   . ALA B 1 563 ? -18.110  -9.256  59.006  1.00 61.60  ? 623 ALA B O   1 
ATOM   8603  C CB  . ALA B 1 563 ? -15.049  -10.241 59.482  1.00 63.11  ? 623 ALA B CB  1 
ATOM   8604  N N   . GLU B 1 564 ? -16.719  -7.507  59.398  1.00 54.95  ? 624 GLU B N   1 
ATOM   8605  C CA  . GLU B 1 564 ? -17.734  -6.590  60.003  1.00 62.16  ? 624 GLU B CA  1 
ATOM   8606  C C   . GLU B 1 564 ? -18.743  -6.146  58.949  1.00 59.60  ? 624 GLU B C   1 
ATOM   8607  O O   . GLU B 1 564 ? -19.903  -5.916  59.320  1.00 75.41  ? 624 GLU B O   1 
ATOM   8608  C CB  . GLU B 1 564 ? -17.106  -5.350  60.636  1.00 74.36  ? 624 GLU B CB  1 
ATOM   8609  C CG  . GLU B 1 564 ? -16.383  -5.682  61.934  1.00 81.54  ? 624 GLU B CG  1 
ATOM   8610  C CD  . GLU B 1 564 ? -15.478  -4.600  62.483  1.00 80.12  ? 624 GLU B CD  1 
ATOM   8611  O OE1 . GLU B 1 564 ? -15.024  -3.765  61.699  1.00 78.63  ? 624 GLU B OE1 1 
ATOM   8612  O OE2 . GLU B 1 564 ? -15.234  -4.607  63.694  1.00 84.75  ? 624 GLU B OE2 1 
ATOM   8613  N N   . ASN B 1 565 ? -18.318  -6.028  57.695  1.00 62.38  ? 625 ASN B N   1 
ATOM   8614  C CA  . ASN B 1 565 ? -19.182  -5.586  56.566  1.00 60.49  ? 625 ASN B CA  1 
ATOM   8615  C C   . ASN B 1 565 ? -20.031  -6.757  56.070  1.00 51.10  ? 625 ASN B C   1 
ATOM   8616  O O   . ASN B 1 565 ? -21.044  -6.483  55.497  1.00 55.91  ? 625 ASN B O   1 
ATOM   8617  C CB  . ASN B 1 565 ? -18.373  -4.945  55.433  1.00 58.91  ? 625 ASN B CB  1 
ATOM   8618  C CG  . ASN B 1 565 ? -17.891  -3.550  55.776  1.00 58.65  ? 625 ASN B CG  1 
ATOM   8619  O OD1 . ASN B 1 565 ? -18.419  -2.895  56.680  1.00 61.85  ? 625 ASN B OD1 1 
ATOM   8620  N ND2 . ASN B 1 565 ? -16.868  -3.096  55.072  1.00 54.42  ? 625 ASN B ND2 1 
ATOM   8621  N N   . CYS B 1 566 ? -19.634  -8.007  56.292  1.00 57.79  ? 626 CYS B N   1 
ATOM   8622  C CA  . CYS B 1 566 ? -20.415  -9.227  55.920  1.00 62.41  ? 626 CYS B CA  1 
ATOM   8623  C C   . CYS B 1 566 ? -21.485  -9.547  56.956  1.00 67.29  ? 626 CYS B C   1 
ATOM   8624  O O   . CYS B 1 566 ? -22.137  -10.607 56.798  1.00 75.69  ? 626 CYS B O   1 
ATOM   8625  C CB  . CYS B 1 566 ? -19.554  -10.481 55.860  1.00 62.33  ? 626 CYS B CB  1 
ATOM   8626  S SG  . CYS B 1 566 ? -18.410  -10.498 54.461  1.00 64.24  ? 626 CYS B SG  1 
ATOM   8627  N N   . MET B 1 567 ? -21.626  -8.723  58.004  1.00 67.56  ? 627 MET B N   1 
ATOM   8628  C CA  . MET B 1 567 ? -22.432  -9.095  59.197  1.00 61.63  ? 627 MET B CA  1 
ATOM   8629  C C   . MET B 1 567 ? -23.858  -8.597  58.970  1.00 60.18  ? 627 MET B C   1 
ATOM   8630  O O   . MET B 1 567 ? -24.049  -7.381  58.667  1.00 53.77  ? 627 MET B O   1 
ATOM   8631  C CB  . MET B 1 567 ? -21.859  -8.546  60.508  1.00 54.89  ? 627 MET B CB  1 
ATOM   8632  C CG  . MET B 1 567 ? -20.868  -9.510  61.163  1.00 55.12  ? 627 MET B CG  1 
ATOM   8633  S SD  . MET B 1 567 ? -20.054  -8.990  62.714  1.00 62.52  ? 627 MET B SD  1 
ATOM   8634  C CE  . MET B 1 567 ? -20.324  -7.210  62.653  1.00 70.68  ? 627 MET B CE  1 
ATOM   8635  N N   . TYR B 1 568 ? -24.813  -9.526  59.113  1.00 53.68  ? 628 TYR B N   1 
ATOM   8636  C CA  . TYR B 1 568 ? -26.257  -9.235  59.162  1.00 53.46  ? 628 TYR B CA  1 
ATOM   8637  C C   . TYR B 1 568 ? -26.496  -8.150  60.204  1.00 53.31  ? 628 TYR B C   1 
ATOM   8638  O O   . TYR B 1 568 ? -25.930  -8.227  61.299  1.00 58.69  ? 628 TYR B O   1 
ATOM   8639  C CB  . TYR B 1 568 ? -27.031  -10.496 59.514  1.00 53.99  ? 628 TYR B CB  1 
ATOM   8640  C CG  . TYR B 1 568 ? -28.491  -10.270 59.823  1.00 58.41  ? 628 TYR B CG  1 
ATOM   8641  C CD1 . TYR B 1 568 ? -28.921  -10.115 61.135  1.00 58.36  ? 628 TYR B CD1 1 
ATOM   8642  C CD2 . TYR B 1 568 ? -29.447  -10.221 58.819  1.00 51.75  ? 628 TYR B CD2 1 
ATOM   8643  C CE1 . TYR B 1 568 ? -30.259  -9.921  61.439  1.00 47.42  ? 628 TYR B CE1 1 
ATOM   8644  C CE2 . TYR B 1 568 ? -30.788  -10.042 59.107  1.00 47.57  ? 628 TYR B CE2 1 
ATOM   8645  C CZ  . TYR B 1 568 ? -31.194  -9.927  60.420  1.00 45.93  ? 628 TYR B CZ  1 
ATOM   8646  O OH  . TYR B 1 568 ? -32.514  -9.793  60.703  1.00 41.89  ? 628 TYR B OH  1 
ATOM   8647  N N   . THR B 1 569 ? -27.287  -7.147  59.850  1.00 56.08  ? 629 THR B N   1 
ATOM   8648  C CA  . THR B 1 569 ? -27.812  -6.160  60.815  1.00 60.50  ? 629 THR B CA  1 
ATOM   8649  C C   . THR B 1 569 ? -29.328  -6.329  60.814  1.00 60.03  ? 629 THR B C   1 
ATOM   8650  O O   . THR B 1 569 ? -29.951  -6.485  59.768  1.00 65.77  ? 629 THR B O   1 
ATOM   8651  C CB  . THR B 1 569 ? -27.333  -4.739  60.500  1.00 61.67  ? 629 THR B CB  1 
ATOM   8652  O OG1 . THR B 1 569 ? -28.142  -3.873  61.288  1.00 66.30  ? 629 THR B OG1 1 
ATOM   8653  C CG2 . THR B 1 569 ? -27.475  -4.360  59.044  1.00 65.28  ? 629 THR B CG2 1 
ATOM   8654  N N   . PRO B 1 570 ? -29.976  -6.363  61.990  1.00 54.24  ? 630 PRO B N   1 
ATOM   8655  C CA  . PRO B 1 570 ? -31.419  -6.527  62.041  1.00 50.00  ? 630 PRO B CA  1 
ATOM   8656  C C   . PRO B 1 570 ? -32.200  -5.205  62.076  1.00 50.02  ? 630 PRO B C   1 
ATOM   8657  O O   . PRO B 1 570 ? -33.400  -5.255  62.309  1.00 59.71  ? 630 PRO B O   1 
ATOM   8658  C CB  . PRO B 1 570 ? -31.529  -7.335  63.342  1.00 56.11  ? 630 PRO B CB  1 
ATOM   8659  C CG  . PRO B 1 570 ? -30.426  -6.781  64.249  1.00 54.12  ? 630 PRO B CG  1 
ATOM   8660  C CD  . PRO B 1 570 ? -29.349  -6.286  63.316  1.00 55.03  ? 630 PRO B CD  1 
ATOM   8661  N N   . VAL B 1 571 ? -31.555  -4.059  61.837  1.00 52.92  ? 631 VAL B N   1 
ATOM   8662  C CA  . VAL B 1 571 ? -32.296  -2.766  61.686  1.00 62.96  ? 631 VAL B CA  1 
ATOM   8663  C C   . VAL B 1 571 ? -33.329  -2.933  60.546  1.00 63.07  ? 631 VAL B C   1 
ATOM   8664  O O   . VAL B 1 571 ? -33.040  -3.659  59.590  1.00 59.55  ? 631 VAL B O   1 
ATOM   8665  C CB  . VAL B 1 571 ? -31.343  -1.583  61.448  1.00 64.27  ? 631 VAL B CB  1 
ATOM   8666  C CG1 . VAL B 1 571 ? -30.732  -1.661  60.063  1.00 69.97  ? 631 VAL B CG1 1 
ATOM   8667  C CG2 . VAL B 1 571 ? -32.038  -0.242  61.655  1.00 68.57  ? 631 VAL B CG2 1 
ATOM   8668  N N   . TYR B 1 572 ? -34.525  -2.343  60.662  1.00 67.35  ? 632 TYR B N   1 
ATOM   8669  C CA  . TYR B 1 572 ? -35.657  -2.560  59.716  1.00 64.79  ? 632 TYR B CA  1 
ATOM   8670  C C   . TYR B 1 572 ? -35.301  -2.055  58.316  1.00 69.23  ? 632 TYR B C   1 
ATOM   8671  O O   . TYR B 1 572 ? -34.898  -0.872  58.187  1.00 62.70  ? 632 TYR B O   1 
ATOM   8672  C CB  . TYR B 1 572 ? -36.944  -1.876  60.210  1.00 60.95  ? 632 TYR B CB  1 
ATOM   8673  C CG  . TYR B 1 572 ? -37.781  -2.669  61.190  1.00 55.22  ? 632 TYR B CG  1 
ATOM   8674  C CD1 . TYR B 1 572 ? -37.925  -4.057  61.095  1.00 46.00  ? 632 TYR B CD1 1 
ATOM   8675  C CD2 . TYR B 1 572 ? -38.455  -2.016  62.207  1.00 52.06  ? 632 TYR B CD2 1 
ATOM   8676  C CE1 . TYR B 1 572 ? -38.697  -4.776  61.995  1.00 39.64  ? 632 TYR B CE1 1 
ATOM   8677  C CE2 . TYR B 1 572 ? -39.237  -2.724  63.111  1.00 53.96  ? 632 TYR B CE2 1 
ATOM   8678  C CZ  . TYR B 1 572 ? -39.364  -4.103  63.002  1.00 45.86  ? 632 TYR B CZ  1 
ATOM   8679  O OH  . TYR B 1 572 ? -40.155  -4.762  63.892  1.00 42.87  ? 632 TYR B OH  1 
ATOM   8680  N N   . ARG B 1 573 ? -35.475  -2.940  57.323  1.00 85.78  ? 633 ARG B N   1 
ATOM   8681  C CA  . ARG B 1 573 ? -35.197  -2.678  55.878  1.00 93.05  ? 633 ARG B CA  1 
ATOM   8682  C C   . ARG B 1 573 ? -36.397  -1.867  55.352  1.00 85.21  ? 633 ARG B C   1 
ATOM   8683  O O   . ARG B 1 573 ? -37.473  -1.955  55.961  1.00 89.14  ? 633 ARG B O   1 
ATOM   8684  C CB  . ARG B 1 573 ? -34.798  -3.968  55.121  1.00 94.82  ? 633 ARG B CB  1 
ATOM   8685  C CG  . ARG B 1 573 ? -33.293  -4.072  54.826  1.00 110.67 ? 633 ARG B CG  1 
ATOM   8686  C CD  . ARG B 1 573 ? -32.573  -5.426  54.619  1.00 126.51 ? 633 ARG B CD  1 
ATOM   8687  N NE  . ARG B 1 573 ? -31.128  -5.312  54.918  1.00 144.27 ? 633 ARG B NE  1 
ATOM   8688  C CZ  . ARG B 1 573 ? -30.283  -6.311  55.236  1.00 115.74 ? 633 ARG B CZ  1 
ATOM   8689  N NH1 . ARG B 1 573 ? -29.008  -6.061  55.494  1.00 92.72  ? 633 ARG B NH1 1 
ATOM   8690  N NH2 . ARG B 1 573 ? -30.716  -7.555  55.306  1.00 121.66 ? 633 ARG B NH2 1 
ATOM   8691  N N   . ASN B 1 574 ? -36.179  -0.981  54.376  1.00 94.12  ? 634 ASN B N   1 
ATOM   8692  C CA  . ASN B 1 574 ? -37.114  0.128   54.028  1.00 93.35  ? 634 ASN B CA  1 
ATOM   8693  C C   . ASN B 1 574 ? -37.886  -0.252  52.763  1.00 81.95  ? 634 ASN B C   1 
ATOM   8694  O O   . ASN B 1 574 ? -37.234  -0.564  51.757  1.00 71.54  ? 634 ASN B O   1 
ATOM   8695  C CB  . ASN B 1 574 ? -36.378  1.467   53.879  1.00 104.91 ? 634 ASN B CB  1 
ATOM   8696  C CG  . ASN B 1 574 ? -37.269  2.603   53.419  1.00 106.53 ? 634 ASN B CG  1 
ATOM   8697  O OD1 . ASN B 1 574 ? -37.667  2.668   52.254  1.00 79.61  ? 634 ASN B OD1 1 
ATOM   8698  N ND2 . ASN B 1 574 ? -37.577  3.515   54.329  1.00 121.98 ? 634 ASN B ND2 1 
ATOM   8699  N N   . TYR B 1 575 ? -39.225  -0.177  52.820  1.00 87.14  ? 635 TYR B N   1 
ATOM   8700  C CA  . TYR B 1 575 ? -40.159  -0.678  51.778  1.00 82.87  ? 635 TYR B CA  1 
ATOM   8701  C C   . TYR B 1 575 ? -40.870  0.469   51.031  1.00 85.46  ? 635 TYR B C   1 
ATOM   8702  O O   . TYR B 1 575 ? -41.442  0.190   49.971  1.00 88.44  ? 635 TYR B O   1 
ATOM   8703  C CB  . TYR B 1 575 ? -41.143  -1.651  52.418  1.00 74.71  ? 635 TYR B CB  1 
ATOM   8704  C CG  . TYR B 1 575 ? -40.518  -2.898  52.974  1.00 66.72  ? 635 TYR B CG  1 
ATOM   8705  C CD1 . TYR B 1 575 ? -39.853  -3.805  52.169  1.00 73.20  ? 635 TYR B CD1 1 
ATOM   8706  C CD2 . TYR B 1 575 ? -40.669  -3.219  54.303  1.00 69.25  ? 635 TYR B CD2 1 
ATOM   8707  C CE1 . TYR B 1 575 ? -39.317  -4.976  52.683  1.00 77.83  ? 635 TYR B CE1 1 
ATOM   8708  C CE2 . TYR B 1 575 ? -40.156  -4.397  54.836  1.00 75.67  ? 635 TYR B CE2 1 
ATOM   8709  C CZ  . TYR B 1 575 ? -39.473  -5.275  54.019  1.00 72.16  ? 635 TYR B CZ  1 
ATOM   8710  O OH  . TYR B 1 575 ? -38.910  -6.404  54.503  1.00 60.90  ? 635 TYR B OH  1 
ATOM   8711  N N   . ARG B 1 576 ? -40.831  1.722   51.504  1.00 93.08  ? 636 ARG B N   1 
ATOM   8712  C CA  . ARG B 1 576 ? -41.376  2.880   50.736  1.00 91.36  ? 636 ARG B CA  1 
ATOM   8713  C C   . ARG B 1 576 ? -40.553  4.127   51.056  1.00 78.70  ? 636 ARG B C   1 
ATOM   8714  O O   . ARG B 1 576 ? -41.169  5.176   51.103  1.00 63.87  ? 636 ARG B O   1 
ATOM   8715  C CB  . ARG B 1 576 ? -42.858  3.086   51.075  1.00 117.61 ? 636 ARG B CB  1 
ATOM   8716  C CG  . ARG B 1 576 ? -43.868  3.006   49.928  1.00 134.47 ? 636 ARG B CG  1 
ATOM   8717  C CD  . ARG B 1 576 ? -43.553  2.201   48.678  1.00 146.34 ? 636 ARG B CD  1 
ATOM   8718  N NE  . ARG B 1 576 ? -43.560  0.748   48.842  1.00 176.06 ? 636 ARG B NE  1 
ATOM   8719  C CZ  . ARG B 1 576 ? -43.439  -0.126  47.837  1.00 193.30 ? 636 ARG B CZ  1 
ATOM   8720  N NH1 . ARG B 1 576 ? -43.325  0.305   46.589  1.00 216.27 ? 636 ARG B NH1 1 
ATOM   8721  N NH2 . ARG B 1 576 ? -43.415  -1.425  48.083  1.00 171.76 ? 636 ARG B NH2 1 
ATOM   8722  N N   . LEU C 1 25  ? -64.830  -36.256 53.421  1.00 84.88  ? 85  LEU C N   1 
ATOM   8723  C CA  . LEU C 1 25  ? -64.085  -36.233 52.146  1.00 105.25 ? 85  LEU C CA  1 
ATOM   8724  C C   . LEU C 1 25  ? -63.166  -35.011 52.124  1.00 100.47 ? 85  LEU C C   1 
ATOM   8725  O O   . LEU C 1 25  ? -63.550  -33.921 52.539  1.00 93.93  ? 85  LEU C O   1 
ATOM   8726  C CB  . LEU C 1 25  ? -65.026  -36.209 50.930  1.00 118.71 ? 85  LEU C CB  1 
ATOM   8727  C CG  . LEU C 1 25  ? -65.540  -37.570 50.424  1.00 110.95 ? 85  LEU C CG  1 
ATOM   8728  C CD1 . LEU C 1 25  ? -66.964  -37.431 49.915  1.00 105.75 ? 85  LEU C CD1 1 
ATOM   8729  C CD2 . LEU C 1 25  ? -64.636  -38.170 49.336  1.00 101.24 ? 85  LEU C CD2 1 
ATOM   8730  N N   . PRO C 1 26  ? -61.935  -35.183 51.606  1.00 101.81 ? 86  PRO C N   1 
ATOM   8731  C CA  . PRO C 1 26  ? -60.992  -34.082 51.476  1.00 106.69 ? 86  PRO C CA  1 
ATOM   8732  C C   . PRO C 1 26  ? -61.652  -32.875 50.797  1.00 81.79  ? 86  PRO C C   1 
ATOM   8733  O O   . PRO C 1 26  ? -62.392  -33.070 49.896  1.00 79.76  ? 86  PRO C O   1 
ATOM   8734  C CB  . PRO C 1 26  ? -59.826  -34.685 50.647  1.00 133.37 ? 86  PRO C CB  1 
ATOM   8735  C CG  . PRO C 1 26  ? -59.910  -36.179 50.876  1.00 126.62 ? 86  PRO C CG  1 
ATOM   8736  C CD  . PRO C 1 26  ? -61.382  -36.453 51.113  1.00 114.61 ? 86  PRO C CD  1 
ATOM   8737  N N   . VAL C 1 27  ? -61.361  -31.675 51.326  1.00 79.51  ? 87  VAL C N   1 
ATOM   8738  C CA  . VAL C 1 27  ? -61.549  -30.297 50.772  1.00 71.42  ? 87  VAL C CA  1 
ATOM   8739  C C   . VAL C 1 27  ? -60.199  -29.662 50.365  1.00 63.36  ? 87  VAL C C   1 
ATOM   8740  O O   . VAL C 1 27  ? -59.163  -30.199 50.705  1.00 62.89  ? 87  VAL C O   1 
ATOM   8741  C CB  . VAL C 1 27  ? -62.242  -29.474 51.869  1.00 84.06  ? 87  VAL C CB  1 
ATOM   8742  C CG1 . VAL C 1 27  ? -62.242  -27.978 51.584  1.00 90.16  ? 87  VAL C CG1 1 
ATOM   8743  C CG2 . VAL C 1 27  ? -63.655  -29.978 52.128  1.00 94.64  ? 87  VAL C CG2 1 
ATOM   8744  N N   . MET C 1 28  ? -60.221  -28.591 49.596  1.00 68.42  ? 88  MET C N   1 
ATOM   8745  C CA  . MET C 1 28  ? -59.011  -27.969 48.996  1.00 68.11  ? 88  MET C CA  1 
ATOM   8746  C C   . MET C 1 28  ? -58.711  -26.695 49.770  1.00 60.90  ? 88  MET C C   1 
ATOM   8747  O O   . MET C 1 28  ? -59.609  -25.878 49.914  1.00 77.81  ? 88  MET C O   1 
ATOM   8748  C CB  . MET C 1 28  ? -59.276  -27.596 47.536  1.00 72.41  ? 88  MET C CB  1 
ATOM   8749  C CG  . MET C 1 28  ? -58.067  -27.127 46.787  1.00 89.74  ? 88  MET C CG  1 
ATOM   8750  S SD  . MET C 1 28  ? -57.423  -28.471 45.787  1.00 100.16 ? 88  MET C SD  1 
ATOM   8751  C CE  . MET C 1 28  ? -56.337  -29.186 47.019  1.00 117.05 ? 88  MET C CE  1 
ATOM   8752  N N   . PRO C 1 29  ? -57.509  -26.530 50.358  1.00 51.20  ? 89  PRO C N   1 
ATOM   8753  C CA  . PRO C 1 29  ? -57.237  -25.356 51.193  1.00 47.09  ? 89  PRO C CA  1 
ATOM   8754  C C   . PRO C 1 29  ? -56.859  -24.120 50.377  1.00 41.63  ? 89  PRO C C   1 
ATOM   8755  O O   . PRO C 1 29  ? -55.727  -23.919 50.213  1.00 42.73  ? 89  PRO C O   1 
ATOM   8756  C CB  . PRO C 1 29  ? -56.073  -25.832 52.074  1.00 49.57  ? 89  PRO C CB  1 
ATOM   8757  C CG  . PRO C 1 29  ? -55.359  -26.870 51.229  1.00 49.32  ? 89  PRO C CG  1 
ATOM   8758  C CD  . PRO C 1 29  ? -56.416  -27.509 50.356  1.00 49.67  ? 89  PRO C CD  1 
ATOM   8759  N N   . TRP C 1 30  ? -57.814  -23.358 49.857  1.00 46.84  ? 90  TRP C N   1 
ATOM   8760  C CA  . TRP C 1 30  ? -57.562  -22.179 48.984  1.00 54.55  ? 90  TRP C CA  1 
ATOM   8761  C C   . TRP C 1 30  ? -56.988  -21.045 49.828  1.00 49.16  ? 90  TRP C C   1 
ATOM   8762  O O   . TRP C 1 30  ? -57.465  -20.872 50.931  1.00 50.40  ? 90  TRP C O   1 
ATOM   8763  C CB  . TRP C 1 30  ? -58.848  -21.744 48.240  1.00 63.54  ? 90  TRP C CB  1 
ATOM   8764  C CG  . TRP C 1 30  ? -59.294  -22.779 47.261  1.00 61.78  ? 90  TRP C CG  1 
ATOM   8765  C CD1 . TRP C 1 30  ? -60.304  -23.686 47.397  1.00 60.54  ? 90  TRP C CD1 1 
ATOM   8766  C CD2 . TRP C 1 30  ? -58.640  -23.079 46.023  1.00 60.19  ? 90  TRP C CD2 1 
ATOM   8767  N NE1 . TRP C 1 30  ? -60.362  -24.498 46.297  1.00 60.07  ? 90  TRP C NE1 1 
ATOM   8768  C CE2 . TRP C 1 30  ? -59.346  -24.156 45.444  1.00 61.04  ? 90  TRP C CE2 1 
ATOM   8769  C CE3 . TRP C 1 30  ? -57.577  -22.497 45.324  1.00 54.78  ? 90  TRP C CE3 1 
ATOM   8770  C CZ2 . TRP C 1 30  ? -58.974  -24.705 44.221  1.00 55.56  ? 90  TRP C CZ2 1 
ATOM   8771  C CZ3 . TRP C 1 30  ? -57.203  -23.052 44.122  1.00 55.64  ? 90  TRP C CZ3 1 
ATOM   8772  C CH2 . TRP C 1 30  ? -57.900  -24.133 43.578  1.00 54.42  ? 90  TRP C CH2 1 
ATOM   8773  N N   . ALA C 1 31  ? -55.966  -20.357 49.338  1.00 47.25  ? 91  ALA C N   1 
ATOM   8774  C CA  . ALA C 1 31  ? -55.357  -19.215 50.043  1.00 51.73  ? 91  ALA C CA  1 
ATOM   8775  C C   . ALA C 1 31  ? -55.538  -17.991 49.155  1.00 52.12  ? 91  ALA C C   1 
ATOM   8776  O O   . ALA C 1 31  ? -55.373  -18.125 47.940  1.00 50.57  ? 91  ALA C O   1 
ATOM   8777  C CB  . ALA C 1 31  ? -53.914  -19.502 50.329  1.00 53.60  ? 91  ALA C CB  1 
ATOM   8778  N N   . THR C 1 32  ? -55.924  -16.863 49.738  1.00 54.47  ? 92  THR C N   1 
ATOM   8779  C CA  . THR C 1 32  ? -56.212  -15.608 49.001  1.00 57.07  ? 92  THR C CA  1 
ATOM   8780  C C   . THR C 1 32  ? -55.072  -14.630 49.286  1.00 55.11  ? 92  THR C C   1 
ATOM   8781  O O   . THR C 1 32  ? -54.698  -14.504 50.465  1.00 72.27  ? 92  THR C O   1 
ATOM   8782  C CB  . THR C 1 32  ? -57.594  -15.059 49.388  1.00 72.73  ? 92  THR C CB  1 
ATOM   8783  O OG1 . THR C 1 32  ? -57.679  -13.704 48.938  1.00 89.92  ? 92  THR C OG1 1 
ATOM   8784  C CG2 . THR C 1 32  ? -57.880  -15.112 50.880  1.00 75.98  ? 92  THR C CG2 1 
ATOM   8785  N N   . SER C 1 33  ? -54.556  -13.935 48.274  1.00 52.99  ? 93  SER C N   1 
ATOM   8786  C CA  . SER C 1 33  ? -53.572  -12.833 48.444  1.00 52.13  ? 93  SER C CA  1 
ATOM   8787  C C   . SER C 1 33  ? -53.845  -11.724 47.428  1.00 48.88  ? 93  SER C C   1 
ATOM   8788  O O   . SER C 1 33  ? -54.251  -12.057 46.296  1.00 53.50  ? 93  SER C O   1 
ATOM   8789  C CB  . SER C 1 33  ? -52.179  -13.342 48.280  1.00 55.82  ? 93  SER C CB  1 
ATOM   8790  O OG  . SER C 1 33  ? -51.955  -13.698 46.923  1.00 61.34  ? 93  SER C OG  1 
ATOM   8791  N N   . VAL C 1 34  ? -53.584  -10.469 47.808  1.00 46.79  ? 94  VAL C N   1 
ATOM   8792  C CA  . VAL C 1 34  ? -53.615  -9.282  46.901  1.00 43.23  ? 94  VAL C CA  1 
ATOM   8793  C C   . VAL C 1 34  ? -52.669  -9.558  45.741  1.00 45.12  ? 94  VAL C C   1 
ATOM   8794  O O   . VAL C 1 34  ? -51.510  -9.857  46.020  1.00 59.62  ? 94  VAL C O   1 
ATOM   8795  C CB  . VAL C 1 34  ? -53.184  -7.992  47.613  1.00 43.21  ? 94  VAL C CB  1 
ATOM   8796  C CG1 . VAL C 1 34  ? -53.142  -6.800  46.673  1.00 45.00  ? 94  VAL C CG1 1 
ATOM   8797  C CG2 . VAL C 1 34  ? -54.076  -7.702  48.794  1.00 49.80  ? 94  VAL C CG2 1 
ATOM   8798  N N   . ALA C 1 35  ? -53.149  -9.458  44.504  1.00 43.51  ? 95  ALA C N   1 
ATOM   8799  C CA  . ALA C 1 35  ? -52.336  -9.593  43.277  1.00 43.33  ? 95  ALA C CA  1 
ATOM   8800  C C   . ALA C 1 35  ? -51.665  -8.253  42.943  1.00 47.68  ? 95  ALA C C   1 
ATOM   8801  O O   . ALA C 1 35  ? -52.352  -7.149  43.002  1.00 39.26  ? 95  ALA C O   1 
ATOM   8802  C CB  . ALA C 1 35  ? -53.203  -10.065 42.145  1.00 49.23  ? 95  ALA C CB  1 
ATOM   8803  N N   . SER C 1 36  ? -50.368  -8.333  42.607  1.00 50.69  ? 96  SER C N   1 
ATOM   8804  C CA  . SER C 1 36  ? -49.567  -7.209  42.056  1.00 53.20  ? 96  SER C CA  1 
ATOM   8805  C C   . SER C 1 36  ? -48.496  -7.730  41.076  1.00 53.36  ? 96  SER C C   1 
ATOM   8806  O O   . SER C 1 36  ? -48.422  -8.984  40.871  1.00 54.86  ? 96  SER C O   1 
ATOM   8807  C CB  . SER C 1 36  ? -49.007  -6.403  43.174  1.00 56.12  ? 96  SER C CB  1 
ATOM   8808  O OG  . SER C 1 36  ? -49.994  -6.141  44.147  1.00 68.10  ? 96  SER C OG  1 
ATOM   8809  N N   . GLY C 1 37  ? -47.759  -6.811  40.432  1.00 42.97  ? 97  GLY C N   1 
ATOM   8810  C CA  . GLY C 1 37  ? -46.718  -7.118  39.430  1.00 41.73  ? 97  GLY C CA  1 
ATOM   8811  C C   . GLY C 1 37  ? -47.158  -8.208  38.453  1.00 39.72  ? 97  GLY C C   1 
ATOM   8812  O O   . GLY C 1 37  ? -48.277  -8.172  37.991  1.00 41.27  ? 97  GLY C O   1 
ATOM   8813  N N   . TYR C 1 38  ? -46.297  -9.166  38.141  1.00 45.66  ? 98  TYR C N   1 
ATOM   8814  C CA  . TYR C 1 38  ? -46.529  -10.212 37.100  1.00 48.83  ? 98  TYR C CA  1 
ATOM   8815  C C   . TYR C 1 38  ? -47.663  -11.168 37.497  1.00 46.98  ? 98  TYR C C   1 
ATOM   8816  O O   . TYR C 1 38  ? -48.295  -11.670 36.545  1.00 45.62  ? 98  TYR C O   1 
ATOM   8817  C CB  . TYR C 1 38  ? -45.243  -10.982 36.760  1.00 55.05  ? 98  TYR C CB  1 
ATOM   8818  C CG  . TYR C 1 38  ? -44.367  -10.265 35.762  1.00 55.73  ? 98  TYR C CG  1 
ATOM   8819  C CD1 . TYR C 1 38  ? -44.712  -10.225 34.426  1.00 51.74  ? 98  TYR C CD1 1 
ATOM   8820  C CD2 . TYR C 1 38  ? -43.235  -9.571  36.160  1.00 56.85  ? 98  TYR C CD2 1 
ATOM   8821  C CE1 . TYR C 1 38  ? -43.952  -9.527  33.506  1.00 55.26  ? 98  TYR C CE1 1 
ATOM   8822  C CE2 . TYR C 1 38  ? -42.467  -8.868  35.250  1.00 57.29  ? 98  TYR C CE2 1 
ATOM   8823  C CZ  . TYR C 1 38  ? -42.818  -8.854  33.911  1.00 59.61  ? 98  TYR C CZ  1 
ATOM   8824  O OH  . TYR C 1 38  ? -42.090  -8.165  32.976  1.00 72.64  ? 98  TYR C OH  1 
ATOM   8825  N N   . THR C 1 39  ? -47.976  -11.362 38.787  1.00 48.74  ? 99  THR C N   1 
ATOM   8826  C CA  . THR C 1 39  ? -49.130  -12.210 39.206  1.00 51.32  ? 99  THR C CA  1 
ATOM   8827  C C   . THR C 1 39  ? -50.419  -11.593 38.653  1.00 50.83  ? 99  THR C C   1 
ATOM   8828  O O   . THR C 1 39  ? -51.179  -12.340 37.995  1.00 40.91  ? 99  THR C O   1 
ATOM   8829  C CB  . THR C 1 39  ? -49.274  -12.386 40.719  1.00 53.12  ? 99  THR C CB  1 
ATOM   8830  O OG1 . THR C 1 39  ? -48.009  -12.435 41.363  1.00 63.58  ? 99  THR C OG1 1 
ATOM   8831  C CG2 . THR C 1 39  ? -50.000  -13.670 41.031  1.00 56.56  ? 99  THR C CG2 1 
ATOM   8832  N N   . LEU C 1 40  ? -50.605  -10.279 38.871  1.00 44.84  ? 100 LEU C N   1 
ATOM   8833  C CA  . LEU C 1 40  ? -51.754  -9.485  38.354  1.00 48.01  ? 100 LEU C CA  1 
ATOM   8834  C C   . LEU C 1 40  ? -51.805  -9.526  36.813  1.00 50.47  ? 100 LEU C C   1 
ATOM   8835  O O   . LEU C 1 40  ? -52.889  -9.740  36.278  1.00 46.08  ? 100 LEU C O   1 
ATOM   8836  C CB  . LEU C 1 40  ? -51.642  -8.047  38.884  1.00 52.02  ? 100 LEU C CB  1 
ATOM   8837  C CG  . LEU C 1 40  ? -52.627  -7.019  38.285  1.00 49.73  ? 100 LEU C CG  1 
ATOM   8838  C CD1 . LEU C 1 40  ? -54.055  -7.454  38.486  1.00 49.36  ? 100 LEU C CD1 1 
ATOM   8839  C CD2 . LEU C 1 40  ? -52.422  -5.637  38.864  1.00 54.98  ? 100 LEU C CD2 1 
ATOM   8840  N N   . LEU C 1 41  ? -50.689  -9.293  36.112  1.00 54.55  ? 101 LEU C N   1 
ATOM   8841  C CA  . LEU C 1 41  ? -50.662  -9.208  34.624  1.00 50.99  ? 101 LEU C CA  1 
ATOM   8842  C C   . LEU C 1 41  ? -50.981  -10.572 34.018  1.00 49.25  ? 101 LEU C C   1 
ATOM   8843  O O   . LEU C 1 41  ? -51.700  -10.589 33.012  1.00 56.68  ? 101 LEU C O   1 
ATOM   8844  C CB  . LEU C 1 41  ? -49.300  -8.712  34.148  1.00 51.92  ? 101 LEU C CB  1 
ATOM   8845  C CG  . LEU C 1 41  ? -48.918  -7.306  34.610  1.00 53.02  ? 101 LEU C CG  1 
ATOM   8846  C CD1 . LEU C 1 41  ? -47.509  -6.968  34.179  1.00 52.90  ? 101 LEU C CD1 1 
ATOM   8847  C CD2 . LEU C 1 41  ? -49.863  -6.244  34.079  1.00 56.21  ? 101 LEU C CD2 1 
ATOM   8848  N N   . ARG C 1 42  ? -50.515  -11.665 34.632  1.00 53.14  ? 102 ARG C N   1 
ATOM   8849  C CA  . ARG C 1 42  ? -50.728  -13.062 34.138  1.00 61.67  ? 102 ARG C CA  1 
ATOM   8850  C C   . ARG C 1 42  ? -52.116  -13.601 34.548  1.00 59.50  ? 102 ARG C C   1 
ATOM   8851  O O   . ARG C 1 42  ? -52.462  -14.761 34.166  1.00 54.92  ? 102 ARG C O   1 
ATOM   8852  C CB  . ARG C 1 42  ? -49.625  -13.986 34.655  1.00 64.62  ? 102 ARG C CB  1 
ATOM   8853  C CG  . ARG C 1 42  ? -48.243  -13.622 34.136  1.00 66.41  ? 102 ARG C CG  1 
ATOM   8854  C CD  . ARG C 1 42  ? -47.217  -14.743 34.327  1.00 71.84  ? 102 ARG C CD  1 
ATOM   8855  N NE  . ARG C 1 42  ? -45.881  -14.326 34.789  1.00 74.06  ? 102 ARG C NE  1 
ATOM   8856  C CZ  . ARG C 1 42  ? -44.931  -13.772 34.020  1.00 65.86  ? 102 ARG C CZ  1 
ATOM   8857  N NH1 . ARG C 1 42  ? -45.172  -13.484 32.753  1.00 62.85  ? 102 ARG C NH1 1 
ATOM   8858  N NH2 . ARG C 1 42  ? -43.777  -13.410 34.547  1.00 59.02  ? 102 ARG C NH2 1 
ATOM   8859  N N   . ASP C 1 43  ? -52.872  -12.833 35.347  1.00 49.04  ? 103 ASP C N   1 
ATOM   8860  C CA  . ASP C 1 43  ? -54.275  -13.130 35.744  1.00 49.07  ? 103 ASP C CA  1 
ATOM   8861  C C   . ASP C 1 43  ? -55.251  -12.511 34.746  1.00 48.11  ? 103 ASP C C   1 
ATOM   8862  O O   . ASP C 1 43  ? -55.505  -11.302 34.719  1.00 41.60  ? 103 ASP C O   1 
ATOM   8863  C CB  . ASP C 1 43  ? -54.568  -12.648 37.166  1.00 56.20  ? 103 ASP C CB  1 
ATOM   8864  C CG  . ASP C 1 43  ? -55.946  -12.947 37.696  1.00 57.36  ? 103 ASP C CG  1 
ATOM   8865  O OD1 . ASP C 1 43  ? -56.626  -13.845 37.122  1.00 71.95  ? 103 ASP C OD1 1 
ATOM   8866  O OD2 . ASP C 1 43  ? -56.281  -12.310 38.699  1.00 58.75  ? 103 ASP C OD2 1 
ATOM   8867  N N   . PRO C 1 44  ? -55.907  -13.347 33.927  1.00 48.42  ? 104 PRO C N   1 
ATOM   8868  C CA  . PRO C 1 44  ? -56.852  -12.829 32.954  1.00 51.11  ? 104 PRO C CA  1 
ATOM   8869  C C   . PRO C 1 44  ? -57.997  -12.058 33.621  1.00 57.32  ? 104 PRO C C   1 
ATOM   8870  O O   . PRO C 1 44  ? -58.247  -10.965 33.164  1.00 72.46  ? 104 PRO C O   1 
ATOM   8871  C CB  . PRO C 1 44  ? -57.380  -14.062 32.223  1.00 53.76  ? 104 PRO C CB  1 
ATOM   8872  C CG  . PRO C 1 44  ? -56.518  -15.221 32.656  1.00 49.49  ? 104 PRO C CG  1 
ATOM   8873  C CD  . PRO C 1 44  ? -55.805  -14.813 33.921  1.00 51.77  ? 104 PRO C CD  1 
ATOM   8874  N N   . HIS C 1 45  ? -58.627  -12.617 34.664  1.00 60.63  ? 105 HIS C N   1 
ATOM   8875  C CA  . HIS C 1 45  ? -59.788  -12.017 35.382  1.00 63.51  ? 105 HIS C CA  1 
ATOM   8876  C C   . HIS C 1 45  ? -59.554  -10.511 35.659  1.00 58.61  ? 105 HIS C C   1 
ATOM   8877  O O   . HIS C 1 45  ? -60.493  -9.703  35.472  1.00 48.53  ? 105 HIS C O   1 
ATOM   8878  C CB  . HIS C 1 45  ? -60.103  -12.814 36.657  1.00 72.88  ? 105 HIS C CB  1 
ATOM   8879  C CG  . HIS C 1 45  ? -61.480  -12.578 37.192  1.00 84.65  ? 105 HIS C CG  1 
ATOM   8880  N ND1 . HIS C 1 45  ? -62.018  -11.310 37.405  1.00 79.51  ? 105 HIS C ND1 1 
ATOM   8881  C CD2 . HIS C 1 45  ? -62.453  -13.456 37.530  1.00 87.08  ? 105 HIS C CD2 1 
ATOM   8882  C CE1 . HIS C 1 45  ? -63.234  -11.413 37.886  1.00 76.30  ? 105 HIS C CE1 1 
ATOM   8883  N NE2 . HIS C 1 45  ? -63.529  -12.719 37.968  1.00 92.10  ? 105 HIS C NE2 1 
ATOM   8884  N N   . HIS C 1 46  ? -58.349  -10.115 36.076  1.00 54.24  ? 106 HIS C N   1 
ATOM   8885  C CA  . HIS C 1 46  ? -58.051  -8.714  36.478  1.00 52.31  ? 106 HIS C CA  1 
ATOM   8886  C C   . HIS C 1 46  ? -57.208  -7.982  35.429  1.00 52.18  ? 106 HIS C C   1 
ATOM   8887  O O   . HIS C 1 46  ? -57.253  -6.728  35.414  1.00 52.88  ? 106 HIS C O   1 
ATOM   8888  C CB  . HIS C 1 46  ? -57.355  -8.714  37.844  1.00 61.38  ? 106 HIS C CB  1 
ATOM   8889  C CG  . HIS C 1 46  ? -58.217  -9.267  38.930  1.00 65.89  ? 106 HIS C CG  1 
ATOM   8890  N ND1 . HIS C 1 46  ? -59.465  -8.747  39.210  1.00 66.14  ? 106 HIS C ND1 1 
ATOM   8891  C CD2 . HIS C 1 46  ? -58.041  -10.315 39.766  1.00 68.50  ? 106 HIS C CD2 1 
ATOM   8892  C CE1 . HIS C 1 46  ? -60.013  -9.446  40.178  1.00 73.07  ? 106 HIS C CE1 1 
ATOM   8893  N NE2 . HIS C 1 46  ? -59.167  -10.427 40.522  1.00 68.34  ? 106 HIS C NE2 1 
ATOM   8894  N N   . ASN C 1 47  ? -56.408  -8.687  34.624  1.00 46.86  ? 107 ASN C N   1 
ATOM   8895  C CA  . ASN C 1 47  ? -55.348  -8.014  33.834  1.00 47.42  ? 107 ASN C CA  1 
ATOM   8896  C C   . ASN C 1 47  ? -55.975  -6.987  32.888  1.00 48.78  ? 107 ASN C C   1 
ATOM   8897  O O   . ASN C 1 47  ? -56.748  -7.397  32.012  1.00 52.11  ? 107 ASN C O   1 
ATOM   8898  C CB  . ASN C 1 47  ? -54.482  -8.980  33.037  1.00 47.35  ? 107 ASN C CB  1 
ATOM   8899  C CG  . ASN C 1 47  ? -53.710  -8.253  31.961  1.00 44.73  ? 107 ASN C CG  1 
ATOM   8900  O OD1 . ASN C 1 47  ? -52.944  -7.359  32.252  1.00 46.97  ? 107 ASN C OD1 1 
ATOM   8901  N ND2 . ASN C 1 47  ? -53.983  -8.559  30.716  1.00 47.28  ? 107 ASN C ND2 1 
ATOM   8902  N N   . LYS C 1 48  ? -55.592  -5.716  33.017  1.00 46.08  ? 108 LYS C N   1 
ATOM   8903  C CA  . LYS C 1 48  ? -56.071  -4.631  32.123  1.00 51.37  ? 108 LYS C CA  1 
ATOM   8904  C C   . LYS C 1 48  ? -55.005  -4.252  31.087  1.00 52.22  ? 108 LYS C C   1 
ATOM   8905  O O   . LYS C 1 48  ? -55.286  -3.296  30.348  1.00 63.00  ? 108 LYS C O   1 
ATOM   8906  C CB  . LYS C 1 48  ? -56.471  -3.391  32.932  1.00 50.31  ? 108 LYS C CB  1 
ATOM   8907  C CG  . LYS C 1 48  ? -57.569  -3.636  33.964  1.00 51.26  ? 108 LYS C CG  1 
ATOM   8908  C CD  . LYS C 1 48  ? -57.909  -2.428  34.827  1.00 55.59  ? 108 LYS C CD  1 
ATOM   8909  C CE  . LYS C 1 48  ? -58.130  -1.164  34.009  1.00 63.66  ? 108 LYS C CE  1 
ATOM   8910  N NZ  . LYS C 1 48  ? -58.483  0.023   34.834  1.00 63.19  ? 108 LYS C NZ  1 
ATOM   8911  N N   . GLY C 1 49  ? -53.848  -4.932  31.002  1.00 46.49  ? 109 GLY C N   1 
ATOM   8912  C CA  . GLY C 1 49  ? -52.765  -4.496  30.086  1.00 44.98  ? 109 GLY C CA  1 
ATOM   8913  C C   . GLY C 1 49  ? -52.565  -2.979  30.161  1.00 45.01  ? 109 GLY C C   1 
ATOM   8914  O O   . GLY C 1 49  ? -52.750  -2.423  31.260  1.00 53.48  ? 109 GLY C O   1 
ATOM   8915  N N   . LEU C 1 50  ? -52.311  -2.287  29.051  1.00 46.51  ? 110 LEU C N   1 
ATOM   8916  C CA  . LEU C 1 50  ? -51.929  -0.833  29.086  1.00 54.58  ? 110 LEU C CA  1 
ATOM   8917  C C   . LEU C 1 50  ? -53.076  0.047   29.585  1.00 51.92  ? 110 LEU C C   1 
ATOM   8918  O O   . LEU C 1 50  ? -52.853  1.277   29.661  1.00 50.11  ? 110 LEU C O   1 
ATOM   8919  C CB  . LEU C 1 50  ? -51.540  -0.308  27.699  1.00 66.75  ? 110 LEU C CB  1 
ATOM   8920  C CG  . LEU C 1 50  ? -50.499  -1.082  26.906  1.00 72.93  ? 110 LEU C CG  1 
ATOM   8921  C CD1 . LEU C 1 50  ? -51.187  -1.910  25.839  1.00 78.63  ? 110 LEU C CD1 1 
ATOM   8922  C CD2 . LEU C 1 50  ? -49.507  -0.141  26.259  1.00 69.51  ? 110 LEU C CD2 1 
ATOM   8923  N N   . ALA C 1 51  ? -54.256  -0.523  29.856  1.00 55.97  ? 111 ALA C N   1 
ATOM   8924  C CA  . ALA C 1 51  ? -55.451  0.225   30.307  1.00 56.50  ? 111 ALA C CA  1 
ATOM   8925  C C   . ALA C 1 51  ? -55.356  0.487   31.808  1.00 52.16  ? 111 ALA C C   1 
ATOM   8926  O O   . ALA C 1 51  ? -56.096  1.386   32.290  1.00 64.30  ? 111 ALA C O   1 
ATOM   8927  C CB  . ALA C 1 51  ? -56.735  -0.474  29.937  1.00 56.78  ? 111 ALA C CB  1 
ATOM   8928  N N   . PHE C 1 52  ? -54.460  -0.211  32.507  1.00 50.82  ? 112 PHE C N   1 
ATOM   8929  C CA  . PHE C 1 52  ? -54.032  0.162   33.888  1.00 49.58  ? 112 PHE C CA  1 
ATOM   8930  C C   . PHE C 1 52  ? -53.625  1.651   33.949  1.00 50.04  ? 112 PHE C C   1 
ATOM   8931  O O   . PHE C 1 52  ? -52.680  2.047   33.306  1.00 52.21  ? 112 PHE C O   1 
ATOM   8932  C CB  . PHE C 1 52  ? -52.882  -0.719  34.360  1.00 43.21  ? 112 PHE C CB  1 
ATOM   8933  C CG  . PHE C 1 52  ? -53.317  -2.034  34.918  1.00 41.35  ? 112 PHE C CG  1 
ATOM   8934  C CD1 . PHE C 1 52  ? -54.154  -2.069  36.023  1.00 40.12  ? 112 PHE C CD1 1 
ATOM   8935  C CD2 . PHE C 1 52  ? -52.883  -3.227  34.354  1.00 40.62  ? 112 PHE C CD2 1 
ATOM   8936  C CE1 . PHE C 1 52  ? -54.553  -3.285  36.556  1.00 43.02  ? 112 PHE C CE1 1 
ATOM   8937  C CE2 . PHE C 1 52  ? -53.289  -4.446  34.884  1.00 46.17  ? 112 PHE C CE2 1 
ATOM   8938  C CZ  . PHE C 1 52  ? -54.121  -4.475  35.990  1.00 45.81  ? 112 PHE C CZ  1 
ATOM   8939  N N   . THR C 1 53  ? -54.340  2.459   34.713  1.00 59.32  ? 113 THR C N   1 
ATOM   8940  C CA  . THR C 1 53  ? -54.049  3.902   34.928  1.00 64.16  ? 113 THR C CA  1 
ATOM   8941  C C   . THR C 1 53  ? -52.723  4.034   35.682  1.00 64.35  ? 113 THR C C   1 
ATOM   8942  O O   . THR C 1 53  ? -52.330  3.069   36.353  1.00 65.11  ? 113 THR C O   1 
ATOM   8943  C CB  . THR C 1 53  ? -55.192  4.602   35.679  1.00 73.26  ? 113 THR C CB  1 
ATOM   8944  O OG1 . THR C 1 53  ? -55.325  4.062   37.002  1.00 65.35  ? 113 THR C OG1 1 
ATOM   8945  C CG2 . THR C 1 53  ? -56.506  4.473   34.932  1.00 79.48  ? 113 THR C CG2 1 
ATOM   8946  N N   . GLU C 1 54  ? -52.061  5.185   35.556  1.00 71.72  ? 114 GLU C N   1 
ATOM   8947  C CA  . GLU C 1 54  ? -50.802  5.542   36.264  1.00 73.93  ? 114 GLU C CA  1 
ATOM   8948  C C   . GLU C 1 54  ? -50.937  5.132   37.736  1.00 76.77  ? 114 GLU C C   1 
ATOM   8949  O O   . GLU C 1 54  ? -50.055  4.381   38.224  1.00 73.27  ? 114 GLU C O   1 
ATOM   8950  C CB  . GLU C 1 54  ? -50.545  7.034   36.043  1.00 78.18  ? 114 GLU C CB  1 
ATOM   8951  C CG  . GLU C 1 54  ? -49.335  7.588   36.774  1.00 97.30  ? 114 GLU C CG  1 
ATOM   8952  C CD  . GLU C 1 54  ? -48.561  8.703   36.053  1.00 108.19 ? 114 GLU C CD  1 
ATOM   8953  O OE1 . GLU C 1 54  ? -48.732  8.882   34.811  1.00 79.96  ? 114 GLU C OE1 1 
ATOM   8954  O OE2 . GLU C 1 54  ? -47.760  9.400   36.730  1.00 122.37 ? 114 GLU C OE2 1 
ATOM   8955  N N   . GLU C 1 55  ? -52.032  5.563   38.378  1.00 80.07  ? 115 GLU C N   1 
ATOM   8956  C CA  . GLU C 1 55  ? -52.354  5.379   39.829  1.00 73.31  ? 115 GLU C CA  1 
ATOM   8957  C C   . GLU C 1 55  ? -52.397  3.877   40.148  1.00 57.67  ? 115 GLU C C   1 
ATOM   8958  O O   . GLU C 1 55  ? -51.856  3.464   41.168  1.00 56.84  ? 115 GLU C O   1 
ATOM   8959  C CB  . GLU C 1 55  ? -53.666  6.087   40.199  1.00 75.62  ? 115 GLU C CB  1 
ATOM   8960  C CG  . GLU C 1 55  ? -53.798  7.538   39.676  1.00 85.17  ? 115 GLU C CG  1 
ATOM   8961  C CD  . GLU C 1 55  ? -54.516  7.801   38.334  1.00 89.68  ? 115 GLU C CD  1 
ATOM   8962  O OE1 . GLU C 1 55  ? -55.627  7.257   38.103  1.00 85.76  ? 115 GLU C OE1 1 
ATOM   8963  O OE2 . GLU C 1 55  ? -53.987  8.583   37.504  1.00 82.61  ? 115 GLU C OE2 1 
ATOM   8964  N N   . GLU C 1 56  ? -52.997  3.086   39.270  1.00 56.75  ? 116 GLU C N   1 
ATOM   8965  C CA  . GLU C 1 56  ? -53.165  1.618   39.447  1.00 63.88  ? 116 GLU C CA  1 
ATOM   8966  C C   . GLU C 1 56  ? -51.818  0.902   39.359  1.00 66.45  ? 116 GLU C C   1 
ATOM   8967  O O   . GLU C 1 56  ? -51.672  -0.135  40.071  1.00 58.97  ? 116 GLU C O   1 
ATOM   8968  C CB  . GLU C 1 56  ? -54.086  1.050   38.369  1.00 69.68  ? 116 GLU C CB  1 
ATOM   8969  C CG  . GLU C 1 56  ? -55.525  1.476   38.548  1.00 75.92  ? 116 GLU C CG  1 
ATOM   8970  C CD  . GLU C 1 56  ? -56.495  1.046   37.475  1.00 75.94  ? 116 GLU C CD  1 
ATOM   8971  O OE1 . GLU C 1 56  ? -56.061  0.902   36.329  1.00 63.85  ? 116 GLU C OE1 1 
ATOM   8972  O OE2 . GLU C 1 56  ? -57.701  0.889   37.824  1.00 85.25  ? 116 GLU C OE2 1 
ATOM   8973  N N   . ARG C 1 57  ? -50.910  1.408   38.498  1.00 63.13  ? 117 ARG C N   1 
ATOM   8974  C CA  . ARG C 1 57  ? -49.557  0.837   38.258  1.00 58.45  ? 117 ARG C CA  1 
ATOM   8975  C C   . ARG C 1 57  ? -48.662  1.054   39.494  1.00 64.81  ? 117 ARG C C   1 
ATOM   8976  O O   . ARG C 1 57  ? -48.023  0.062   39.949  1.00 59.89  ? 117 ARG C O   1 
ATOM   8977  C CB  . ARG C 1 57  ? -48.937  1.468   37.012  1.00 53.65  ? 117 ARG C CB  1 
ATOM   8978  C CG  . ARG C 1 57  ? -49.755  1.339   35.737  1.00 49.63  ? 117 ARG C CG  1 
ATOM   8979  C CD  . ARG C 1 57  ? -49.007  1.663   34.442  1.00 48.34  ? 117 ARG C CD  1 
ATOM   8980  N NE  . ARG C 1 57  ? -49.855  1.573   33.264  1.00 45.51  ? 117 ARG C NE  1 
ATOM   8981  C CZ  . ARG C 1 57  ? -49.488  1.860   32.023  1.00 52.09  ? 117 ARG C CZ  1 
ATOM   8982  N NH1 . ARG C 1 57  ? -48.244  2.231   31.769  1.00 49.94  ? 117 ARG C NH1 1 
ATOM   8983  N NH2 . ARG C 1 57  ? -50.373  1.750   31.034  1.00 62.31  ? 117 ARG C NH2 1 
ATOM   8984  N N   . ASP C 1 58  ? -48.600  2.291   40.020  1.00 63.07  ? 118 ASP C N   1 
ATOM   8985  C CA  . ASP C 1 58  ? -47.895  2.617   41.294  1.00 63.02  ? 118 ASP C CA  1 
ATOM   8986  C C   . ASP C 1 58  ? -48.424  1.686   42.380  1.00 60.07  ? 118 ASP C C   1 
ATOM   8987  O O   . ASP C 1 58  ? -47.615  1.025   43.064  1.00 66.21  ? 118 ASP C O   1 
ATOM   8988  C CB  . ASP C 1 58  ? -48.087  4.076   41.705  1.00 61.67  ? 118 ASP C CB  1 
ATOM   8989  C CG  . ASP C 1 58  ? -47.469  5.056   40.731  1.00 85.13  ? 118 ASP C CG  1 
ATOM   8990  O OD1 . ASP C 1 58  ? -46.765  4.592   39.786  1.00 104.11 ? 118 ASP C OD1 1 
ATOM   8991  O OD2 . ASP C 1 58  ? -47.694  6.274   40.915  1.00 94.67  ? 118 ASP C OD2 1 
ATOM   8992  N N   . GLY C 1 59  ? -49.744  1.608   42.469  1.00 54.77  ? 119 GLY C N   1 
ATOM   8993  C CA  . GLY C 1 59  ? -50.470  0.819   43.470  1.00 58.30  ? 119 GLY C CA  1 
ATOM   8994  C C   . GLY C 1 59  ? -50.113  -0.648  43.436  1.00 55.26  ? 119 GLY C C   1 
ATOM   8995  O O   . GLY C 1 59  ? -50.085  -1.222  44.533  1.00 55.32  ? 119 GLY C O   1 
ATOM   8996  N N   . HIS C 1 60  ? -49.871  -1.248  42.261  1.00 57.32  ? 120 HIS C N   1 
ATOM   8997  C CA  . HIS C 1 60  ? -49.742  -2.732  42.173  1.00 62.15  ? 120 HIS C CA  1 
ATOM   8998  C C   . HIS C 1 60  ? -48.410  -3.157  41.574  1.00 57.61  ? 120 HIS C C   1 
ATOM   8999  O O   . HIS C 1 60  ? -48.340  -4.294  41.063  1.00 62.97  ? 120 HIS C O   1 
ATOM   9000  C CB  . HIS C 1 60  ? -50.902  -3.371  41.416  1.00 67.97  ? 120 HIS C CB  1 
ATOM   9001  C CG  . HIS C 1 60  ? -52.202  -3.244  42.130  1.00 70.42  ? 120 HIS C CG  1 
ATOM   9002  N ND1 . HIS C 1 60  ? -53.055  -2.162  41.909  1.00 62.91  ? 120 HIS C ND1 1 
ATOM   9003  C CD2 . HIS C 1 60  ? -52.777  -4.034  43.069  1.00 61.37  ? 120 HIS C CD2 1 
ATOM   9004  C CE1 . HIS C 1 60  ? -54.110  -2.296  42.679  1.00 62.23  ? 120 HIS C CE1 1 
ATOM   9005  N NE2 . HIS C 1 60  ? -53.965  -3.436  43.394  1.00 70.82  ? 120 HIS C NE2 1 
ATOM   9006  N N   . TYR C 1 61  ? -47.399  -2.305  41.663  1.00 55.78  ? 121 TYR C N   1 
ATOM   9007  C CA  . TYR C 1 61  ? -45.999  -2.651  41.313  1.00 55.09  ? 121 TYR C CA  1 
ATOM   9008  C C   . TYR C 1 61  ? -45.952  -3.092  39.855  1.00 51.31  ? 121 TYR C C   1 
ATOM   9009  O O   . TYR C 1 61  ? -45.355  -4.140  39.533  1.00 59.58  ? 121 TYR C O   1 
ATOM   9010  C CB  . TYR C 1 61  ? -45.478  -3.706  42.287  1.00 59.15  ? 121 TYR C CB  1 
ATOM   9011  C CG  . TYR C 1 61  ? -45.717  -3.340  43.730  1.00 68.96  ? 121 TYR C CG  1 
ATOM   9012  C CD1 . TYR C 1 61  ? -45.191  -2.168  44.269  1.00 73.97  ? 121 TYR C CD1 1 
ATOM   9013  C CD2 . TYR C 1 61  ? -46.516  -4.134  44.540  1.00 68.85  ? 121 TYR C CD2 1 
ATOM   9014  C CE1 . TYR C 1 61  ? -45.447  -1.804  45.580  1.00 75.85  ? 121 TYR C CE1 1 
ATOM   9015  C CE2 . TYR C 1 61  ? -46.766  -3.793  45.860  1.00 69.78  ? 121 TYR C CE2 1 
ATOM   9016  C CZ  . TYR C 1 61  ? -46.222  -2.627  46.378  1.00 77.62  ? 121 TYR C CZ  1 
ATOM   9017  O OH  . TYR C 1 61  ? -46.440  -2.242  47.666  1.00 93.03  ? 121 TYR C OH  1 
ATOM   9018  N N   . LEU C 1 62  ? -46.584  -2.284  39.007  1.00 48.93  ? 122 LEU C N   1 
ATOM   9019  C CA  . LEU C 1 62  ? -46.539  -2.426  37.539  1.00 49.44  ? 122 LEU C CA  1 
ATOM   9020  C C   . LEU C 1 62  ? -45.572  -1.407  36.964  1.00 49.94  ? 122 LEU C C   1 
ATOM   9021  O O   . LEU C 1 62  ? -45.035  -1.716  35.890  1.00 56.68  ? 122 LEU C O   1 
ATOM   9022  C CB  . LEU C 1 62  ? -47.936  -2.194  36.961  1.00 51.68  ? 122 LEU C CB  1 
ATOM   9023  C CG  . LEU C 1 62  ? -49.011  -3.133  37.487  1.00 53.94  ? 122 LEU C CG  1 
ATOM   9024  C CD1 . LEU C 1 62  ? -50.301  -2.813  36.755  1.00 51.98  ? 122 LEU C CD1 1 
ATOM   9025  C CD2 . LEU C 1 62  ? -48.588  -4.626  37.399  1.00 44.25  ? 122 LEU C CD2 1 
ATOM   9026  N N   . ARG C 1 63  ? -45.368  -0.249  37.611  1.00 51.15  ? 123 ARG C N   1 
ATOM   9027  C CA  . ARG C 1 63  ? -44.554  0.845   37.012  1.00 45.59  ? 123 ARG C CA  1 
ATOM   9028  C C   . ARG C 1 63  ? -43.262  0.199   36.509  1.00 43.87  ? 123 ARG C C   1 
ATOM   9029  O O   . ARG C 1 63  ? -42.619  -0.528  37.291  1.00 38.49  ? 123 ARG C O   1 
ATOM   9030  C CB  . ARG C 1 63  ? -44.301  1.949   38.032  1.00 54.98  ? 123 ARG C CB  1 
ATOM   9031  C CG  . ARG C 1 63  ? -43.690  3.195   37.438  1.00 61.52  ? 123 ARG C CG  1 
ATOM   9032  C CD  . ARG C 1 63  ? -43.113  4.007   38.567  1.00 71.11  ? 123 ARG C CD  1 
ATOM   9033  N NE  . ARG C 1 63  ? -43.227  5.388   38.140  1.00 80.72  ? 123 ARG C NE  1 
ATOM   9034  C CZ  . ARG C 1 63  ? -43.509  6.420   38.916  1.00 76.42  ? 123 ARG C CZ  1 
ATOM   9035  N NH1 . ARG C 1 63  ? -43.693  6.268   40.214  1.00 77.56  ? 123 ARG C NH1 1 
ATOM   9036  N NH2 . ARG C 1 63  ? -43.597  7.622   38.378  1.00 86.48  ? 123 ARG C NH2 1 
ATOM   9037  N N   . GLY C 1 64  ? -42.956  0.355   35.222  1.00 47.05  ? 124 GLY C N   1 
ATOM   9038  C CA  . GLY C 1 64  ? -41.781  -0.262  34.584  1.00 46.54  ? 124 GLY C CA  1 
ATOM   9039  C C   . GLY C 1 64  ? -42.127  -1.499  33.784  1.00 46.93  ? 124 GLY C C   1 
ATOM   9040  O O   . GLY C 1 64  ? -41.555  -1.655  32.682  1.00 48.13  ? 124 GLY C O   1 
ATOM   9041  N N   . LEU C 1 65  ? -43.000  -2.365  34.297  1.00 46.82  ? 125 LEU C N   1 
ATOM   9042  C CA  . LEU C 1 65  ? -43.403  -3.626  33.610  1.00 52.83  ? 125 LEU C CA  1 
ATOM   9043  C C   . LEU C 1 65  ? -44.294  -3.293  32.403  1.00 51.79  ? 125 LEU C C   1 
ATOM   9044  O O   . LEU C 1 65  ? -44.427  -4.159  31.537  1.00 54.97  ? 125 LEU C O   1 
ATOM   9045  C CB  . LEU C 1 65  ? -44.183  -4.531  34.567  1.00 63.50  ? 125 LEU C CB  1 
ATOM   9046  C CG  . LEU C 1 65  ? -43.448  -5.060  35.791  1.00 64.31  ? 125 LEU C CG  1 
ATOM   9047  C CD1 . LEU C 1 65  ? -42.343  -5.990  35.366  1.00 64.66  ? 125 LEU C CD1 1 
ATOM   9048  C CD2 . LEU C 1 65  ? -42.874  -3.942  36.623  1.00 71.85  ? 125 LEU C CD2 1 
ATOM   9049  N N   . LEU C 1 66  ? -44.939  -2.118  32.387  1.00 52.81  ? 126 LEU C N   1 
ATOM   9050  C CA  . LEU C 1 66  ? -45.640  -1.578  31.185  1.00 47.89  ? 126 LEU C CA  1 
ATOM   9051  C C   . LEU C 1 66  ? -44.908  -0.340  30.696  1.00 42.22  ? 126 LEU C C   1 
ATOM   9052  O O   . LEU C 1 66  ? -44.323  0.413   31.477  1.00 46.07  ? 126 LEU C O   1 
ATOM   9053  C CB  . LEU C 1 66  ? -47.086  -1.197  31.509  1.00 50.86  ? 126 LEU C CB  1 
ATOM   9054  C CG  . LEU C 1 66  ? -47.927  -2.306  32.126  1.00 58.44  ? 126 LEU C CG  1 
ATOM   9055  C CD1 . LEU C 1 66  ? -49.286  -1.752  32.521  1.00 61.11  ? 126 LEU C CD1 1 
ATOM   9056  C CD2 . LEU C 1 66  ? -48.011  -3.509  31.188  1.00 52.33  ? 126 LEU C CD2 1 
ATOM   9057  N N   . PRO C 1 67  ? -44.945  -0.080  29.385  1.00 39.25  ? 127 PRO C N   1 
ATOM   9058  C CA  . PRO C 1 67  ? -44.477  1.188   28.839  1.00 43.08  ? 127 PRO C CA  1 
ATOM   9059  C C   . PRO C 1 67  ? -45.249  2.365   29.428  1.00 41.52  ? 127 PRO C C   1 
ATOM   9060  O O   . PRO C 1 67  ? -46.306  2.169   29.990  1.00 43.12  ? 127 PRO C O   1 
ATOM   9061  C CB  . PRO C 1 67  ? -44.750  1.071   27.337  1.00 44.61  ? 127 PRO C CB  1 
ATOM   9062  C CG  . PRO C 1 67  ? -45.634  -0.159  27.140  1.00 47.11  ? 127 PRO C CG  1 
ATOM   9063  C CD  . PRO C 1 67  ? -45.432  -1.007  28.372  1.00 44.69  ? 127 PRO C CD  1 
ATOM   9064  N N   . PRO C 1 68  ? -44.780  3.616   29.291  1.00 48.08  ? 128 PRO C N   1 
ATOM   9065  C CA  . PRO C 1 68  ? -45.455  4.786   29.874  1.00 55.51  ? 128 PRO C CA  1 
ATOM   9066  C C   . PRO C 1 68  ? -46.930  5.028   29.500  1.00 56.87  ? 128 PRO C C   1 
ATOM   9067  O O   . PRO C 1 68  ? -47.667  5.502   30.332  1.00 58.09  ? 128 PRO C O   1 
ATOM   9068  C CB  . PRO C 1 68  ? -44.671  6.002   29.334  1.00 56.55  ? 128 PRO C CB  1 
ATOM   9069  C CG  . PRO C 1 68  ? -43.344  5.449   28.876  1.00 58.86  ? 128 PRO C CG  1 
ATOM   9070  C CD  . PRO C 1 68  ? -43.565  3.986   28.555  1.00 54.15  ? 128 PRO C CD  1 
ATOM   9071  N N   . ALA C 1 69  ? -47.317  4.690   28.265  1.00 58.80  ? 129 ALA C N   1 
ATOM   9072  C CA  . ALA C 1 69  ? -48.627  5.006   27.642  1.00 55.12  ? 129 ALA C CA  1 
ATOM   9073  C C   . ALA C 1 69  ? -49.753  4.253   28.351  1.00 56.21  ? 129 ALA C C   1 
ATOM   9074  O O   . ALA C 1 69  ? -49.663  3.007   28.490  1.00 46.69  ? 129 ALA C O   1 
ATOM   9075  C CB  . ALA C 1 69  ? -48.623  4.640   26.170  1.00 55.73  ? 129 ALA C CB  1 
ATOM   9076  N N   . VAL C 1 70  ? -50.808  4.999   28.699  1.00 56.85  ? 130 VAL C N   1 
ATOM   9077  C CA  . VAL C 1 70  ? -52.102  4.457   29.199  1.00 52.55  ? 130 VAL C CA  1 
ATOM   9078  C C   . VAL C 1 70  ? -53.146  4.523   28.080  1.00 55.56  ? 130 VAL C C   1 
ATOM   9079  O O   . VAL C 1 70  ? -53.506  5.638   27.646  1.00 57.79  ? 130 VAL C O   1 
ATOM   9080  C CB  . VAL C 1 70  ? -52.568  5.192   30.464  1.00 51.56  ? 130 VAL C CB  1 
ATOM   9081  C CG1 . VAL C 1 70  ? -53.876  4.607   30.982  1.00 52.76  ? 130 VAL C CG1 1 
ATOM   9082  C CG2 . VAL C 1 70  ? -51.477  5.170   31.545  1.00 49.93  ? 130 VAL C CG2 1 
ATOM   9083  N N   . LEU C 1 71  ? -53.621  3.352   27.642  1.00 57.94  ? 131 LEU C N   1 
ATOM   9084  C CA  . LEU C 1 71  ? -54.758  3.214   26.697  1.00 56.20  ? 131 LEU C CA  1 
ATOM   9085  C C   . LEU C 1 71  ? -56.081  3.129   27.449  1.00 56.59  ? 131 LEU C C   1 
ATOM   9086  O O   . LEU C 1 71  ? -56.096  2.573   28.541  1.00 67.54  ? 131 LEU C O   1 
ATOM   9087  C CB  . LEU C 1 71  ? -54.582  1.938   25.869  1.00 62.74  ? 131 LEU C CB  1 
ATOM   9088  C CG  . LEU C 1 71  ? -53.522  1.939   24.773  1.00 63.45  ? 131 LEU C CG  1 
ATOM   9089  C CD1 . LEU C 1 71  ? -53.970  1.044   23.622  1.00 64.77  ? 131 LEU C CD1 1 
ATOM   9090  C CD2 . LEU C 1 71  ? -53.182  3.340   24.256  1.00 66.84  ? 131 LEU C CD2 1 
ATOM   9091  N N   . SER C 1 72  ? -57.156  3.638   26.847  1.00 51.75  ? 132 SER C N   1 
ATOM   9092  C CA  . SER C 1 72  ? -58.561  3.293   27.174  1.00 52.49  ? 132 SER C CA  1 
ATOM   9093  C C   . SER C 1 72  ? -58.905  1.858   26.707  1.00 60.42  ? 132 SER C C   1 
ATOM   9094  O O   . SER C 1 72  ? -58.159  1.271   25.865  1.00 58.06  ? 132 SER C O   1 
ATOM   9095  C CB  . SER C 1 72  ? -59.475  4.268   26.530  1.00 49.66  ? 132 SER C CB  1 
ATOM   9096  O OG  . SER C 1 72  ? -59.473  4.054   25.123  1.00 55.22  ? 132 SER C OG  1 
ATOM   9097  N N   . GLN C 1 73  ? -60.021  1.317   27.206  1.00 52.12  ? 133 GLN C N   1 
ATOM   9098  C CA  . GLN C 1 73  ? -60.538  0.009   26.765  1.00 53.99  ? 133 GLN C CA  1 
ATOM   9099  C C   . GLN C 1 73  ? -60.945  0.137   25.292  1.00 62.92  ? 133 GLN C C   1 
ATOM   9100  O O   . GLN C 1 73  ? -60.797  -0.867  24.569  1.00 59.24  ? 133 GLN C O   1 
ATOM   9101  C CB  . GLN C 1 73  ? -61.680  -0.442  27.678  1.00 61.44  ? 133 GLN C CB  1 
ATOM   9102  C CG  . GLN C 1 73  ? -62.002  -1.931  27.543  1.00 61.92  ? 133 GLN C CG  1 
ATOM   9103  C CD  . GLN C 1 73  ? -63.072  -2.403  28.492  1.00 57.22  ? 133 GLN C CD  1 
ATOM   9104  O OE1 . GLN C 1 73  ? -63.721  -1.595  29.151  1.00 59.45  ? 133 GLN C OE1 1 
ATOM   9105  N NE2 . GLN C 1 73  ? -63.237  -3.718  28.566  1.00 53.31  ? 133 GLN C NE2 1 
ATOM   9106  N N   . GLU C 1 74  ? -61.415  1.324   24.863  1.00 83.93  ? 134 GLU C N   1 
ATOM   9107  C CA  . GLU C 1 74  ? -61.965  1.592   23.495  1.00 77.93  ? 134 GLU C CA  1 
ATOM   9108  C C   . GLU C 1 74  ? -60.839  1.510   22.464  1.00 61.03  ? 134 GLU C C   1 
ATOM   9109  O O   . GLU C 1 74  ? -61.013  0.813   21.425  1.00 54.42  ? 134 GLU C O   1 
ATOM   9110  C CB  . GLU C 1 74  ? -62.603  2.984   23.351  1.00 80.75  ? 134 GLU C CB  1 
ATOM   9111  C CG  . GLU C 1 74  ? -63.840  3.235   24.197  1.00 96.11  ? 134 GLU C CG  1 
ATOM   9112  C CD  . GLU C 1 74  ? -64.888  4.151   23.555  1.00 110.75 ? 134 GLU C CD  1 
ATOM   9113  O OE1 . GLU C 1 74  ? -65.130  5.270   24.080  1.00 123.44 ? 134 GLU C OE1 1 
ATOM   9114  O OE2 . GLU C 1 74  ? -65.482  3.735   22.535  1.00 108.77 ? 134 GLU C OE2 1 
ATOM   9115  N N   . LEU C 1 75  ? -59.740  2.203   22.754  1.00 55.71  ? 135 LEU C N   1 
ATOM   9116  C CA  . LEU C 1 75  ? -58.506  2.144   21.942  1.00 56.59  ? 135 LEU C CA  1 
ATOM   9117  C C   . LEU C 1 75  ? -58.024  0.699   21.908  1.00 50.87  ? 135 LEU C C   1 
ATOM   9118  O O   . LEU C 1 75  ? -57.634  0.268   20.840  1.00 51.53  ? 135 LEU C O   1 
ATOM   9119  C CB  . LEU C 1 75  ? -57.445  3.071   22.530  1.00 57.05  ? 135 LEU C CB  1 
ATOM   9120  C CG  . LEU C 1 75  ? -57.103  4.271   21.652  1.00 55.32  ? 135 LEU C CG  1 
ATOM   9121  C CD1 . LEU C 1 75  ? -58.208  5.320   21.685  1.00 54.24  ? 135 LEU C CD1 1 
ATOM   9122  C CD2 . LEU C 1 75  ? -55.777  4.851   22.107  1.00 61.06  ? 135 LEU C CD2 1 
ATOM   9123  N N   . GLN C 1 76  ? -58.057  -0.011  23.038  1.00 49.80  ? 136 GLN C N   1 
ATOM   9124  C CA  . GLN C 1 76  ? -57.656  -1.452  23.104  1.00 48.30  ? 136 GLN C CA  1 
ATOM   9125  C C   . GLN C 1 76  ? -58.444  -2.246  22.056  1.00 45.68  ? 136 GLN C C   1 
ATOM   9126  O O   . GLN C 1 76  ? -57.798  -3.046  21.304  1.00 47.96  ? 136 GLN C O   1 
ATOM   9127  C CB  . GLN C 1 76  ? -57.856  -2.053  24.502  1.00 45.70  ? 136 GLN C CB  1 
ATOM   9128  C CG  . GLN C 1 76  ? -56.661  -1.883  25.425  1.00 44.51  ? 136 GLN C CG  1 
ATOM   9129  C CD  . GLN C 1 76  ? -56.932  -2.339  26.839  1.00 49.54  ? 136 GLN C CD  1 
ATOM   9130  O OE1 . GLN C 1 76  ? -58.076  -2.466  27.266  1.00 52.15  ? 136 GLN C OE1 1 
ATOM   9131  N NE2 . GLN C 1 76  ? -55.878  -2.611  27.591  1.00 51.19  ? 136 GLN C NE2 1 
ATOM   9132  N N   . ILE C 1 77  ? -59.763  -2.024  22.003  1.00 47.49  ? 137 ILE C N   1 
ATOM   9133  C CA  . ILE C 1 77  ? -60.684  -2.767  21.091  1.00 56.21  ? 137 ILE C CA  1 
ATOM   9134  C C   . ILE C 1 77  ? -60.271  -2.461  19.647  1.00 56.34  ? 137 ILE C C   1 
ATOM   9135  O O   . ILE C 1 77  ? -60.059  -3.439  18.876  1.00 59.38  ? 137 ILE C O   1 
ATOM   9136  C CB  . ILE C 1 77  ? -62.159  -2.468  21.412  1.00 57.69  ? 137 ILE C CB  1 
ATOM   9137  C CG1 . ILE C 1 77  ? -62.518  -3.039  22.788  1.00 56.12  ? 137 ILE C CG1 1 
ATOM   9138  C CG2 . ILE C 1 77  ? -63.082  -3.007  20.331  1.00 59.54  ? 137 ILE C CG2 1 
ATOM   9139  C CD1 . ILE C 1 77  ? -63.931  -2.775  23.228  1.00 58.39  ? 137 ILE C CD1 1 
ATOM   9140  N N   . LYS C 1 78  ? -60.112  -1.169  19.326  1.00 53.74  ? 138 LYS C N   1 
ATOM   9141  C CA  . LYS C 1 78  ? -59.715  -0.682  17.976  1.00 51.58  ? 138 LYS C CA  1 
ATOM   9142  C C   . LYS C 1 78  ? -58.426  -1.408  17.558  1.00 49.07  ? 138 LYS C C   1 
ATOM   9143  O O   . LYS C 1 78  ? -58.375  -1.896  16.425  1.00 52.59  ? 138 LYS C O   1 
ATOM   9144  C CB  . LYS C 1 78  ? -59.610  0.852   17.971  1.00 50.63  ? 138 LYS C CB  1 
ATOM   9145  C CG  . LYS C 1 78  ? -59.223  1.445   16.630  1.00 60.51  ? 138 LYS C CG  1 
ATOM   9146  C CD  . LYS C 1 78  ? -59.811  2.784   16.294  1.00 72.85  ? 138 LYS C CD  1 
ATOM   9147  C CE  . LYS C 1 78  ? -59.455  3.216   14.884  1.00 82.04  ? 138 LYS C CE  1 
ATOM   9148  N NZ  . LYS C 1 78  ? -58.239  4.072   14.852  1.00 81.77  ? 138 LYS C NZ  1 
ATOM   9149  N N   . LYS C 1 79  ? -57.448  -1.482  18.468  1.00 50.77  ? 139 LYS C N   1 
ATOM   9150  C CA  . LYS C 1 79  ? -56.090  -2.050  18.258  1.00 50.31  ? 139 LYS C CA  1 
ATOM   9151  C C   . LYS C 1 79  ? -56.210  -3.557  18.000  1.00 49.19  ? 139 LYS C C   1 
ATOM   9152  O O   . LYS C 1 79  ? -55.634  -4.017  17.018  1.00 47.27  ? 139 LYS C O   1 
ATOM   9153  C CB  . LYS C 1 79  ? -55.239  -1.769  19.493  1.00 48.62  ? 139 LYS C CB  1 
ATOM   9154  C CG  . LYS C 1 79  ? -53.754  -2.023  19.445  1.00 53.16  ? 139 LYS C CG  1 
ATOM   9155  C CD  . LYS C 1 79  ? -53.239  -1.954  20.884  1.00 62.69  ? 139 LYS C CD  1 
ATOM   9156  C CE  . LYS C 1 79  ? -51.829  -1.420  21.027  1.00 76.25  ? 139 LYS C CE  1 
ATOM   9157  N NZ  . LYS C 1 79  ? -51.553  -0.667  22.283  1.00 76.57  ? 139 LYS C NZ  1 
ATOM   9158  N N   . PHE C 1 80  ? -56.915  -4.299  18.849  1.00 47.86  ? 140 PHE C N   1 
ATOM   9159  C CA  . PHE C 1 80  ? -57.068  -5.757  18.641  1.00 54.92  ? 140 PHE C CA  1 
ATOM   9160  C C   . PHE C 1 80  ? -57.809  -6.010  17.328  1.00 60.53  ? 140 PHE C C   1 
ATOM   9161  O O   . PHE C 1 80  ? -57.404  -6.929  16.566  1.00 65.13  ? 140 PHE C O   1 
ATOM   9162  C CB  . PHE C 1 80  ? -57.751  -6.486  19.795  1.00 52.12  ? 140 PHE C CB  1 
ATOM   9163  C CG  . PHE C 1 80  ? -57.460  -7.970  19.763  1.00 50.92  ? 140 PHE C CG  1 
ATOM   9164  C CD1 . PHE C 1 80  ? -56.393  -8.498  20.466  1.00 47.02  ? 140 PHE C CD1 1 
ATOM   9165  C CD2 . PHE C 1 80  ? -58.229  -8.857  19.018  1.00 61.53  ? 140 PHE C CD2 1 
ATOM   9166  C CE1 . PHE C 1 80  ? -56.121  -9.859  20.451  1.00 54.13  ? 140 PHE C CE1 1 
ATOM   9167  C CE2 . PHE C 1 80  ? -57.969  -10.232 19.018  1.00 57.93  ? 140 PHE C CE2 1 
ATOM   9168  C CZ  . PHE C 1 80  ? -56.918  -10.734 19.740  1.00 54.62  ? 140 PHE C CZ  1 
ATOM   9169  N N   . MET C 1 81  ? -58.851  -5.230  17.065  1.00 65.97  ? 141 MET C N   1 
ATOM   9170  C CA  . MET C 1 81  ? -59.699  -5.412  15.845  1.00 67.10  ? 141 MET C CA  1 
ATOM   9171  C C   . MET C 1 81  ? -58.776  -5.256  14.627  1.00 64.38  ? 141 MET C C   1 
ATOM   9172  O O   . MET C 1 81  ? -58.774  -6.154  13.755  1.00 66.26  ? 141 MET C O   1 
ATOM   9173  C CB  . MET C 1 81  ? -60.887  -4.430  15.777  1.00 61.47  ? 141 MET C CB  1 
ATOM   9174  C CG  . MET C 1 81  ? -62.131  -4.843  16.610  1.00 60.03  ? 141 MET C CG  1 
ATOM   9175  S SD  . MET C 1 81  ? -62.673  -6.611  16.477  1.00 59.70  ? 141 MET C SD  1 
ATOM   9176  C CE  . MET C 1 81  ? -63.429  -6.661  14.855  1.00 54.34  ? 141 MET C CE  1 
ATOM   9177  N N   . ASN C 1 82  ? -57.942  -4.216  14.627  1.00 65.36  ? 142 ASN C N   1 
ATOM   9178  C CA  . ASN C 1 82  ? -57.026  -3.889  13.507  1.00 62.98  ? 142 ASN C CA  1 
ATOM   9179  C C   . ASN C 1 82  ? -56.139  -5.102  13.219  1.00 61.13  ? 142 ASN C C   1 
ATOM   9180  O O   . ASN C 1 82  ? -56.103  -5.509  12.044  1.00 54.76  ? 142 ASN C O   1 
ATOM   9181  C CB  . ASN C 1 82  ? -56.227  -2.628  13.822  1.00 72.62  ? 142 ASN C CB  1 
ATOM   9182  C CG  . ASN C 1 82  ? -55.605  -1.941  12.630  1.00 73.87  ? 142 ASN C CG  1 
ATOM   9183  O OD1 . ASN C 1 82  ? -55.877  -2.222  11.464  1.00 65.88  ? 142 ASN C OD1 1 
ATOM   9184  N ND2 . ASN C 1 82  ? -54.795  -0.944  12.929  1.00 80.61  ? 142 ASN C ND2 1 
ATOM   9185  N N   . THR C 1 83  ? -55.493  -5.688  14.243  1.00 64.31  ? 143 THR C N   1 
ATOM   9186  C CA  . THR C 1 83  ? -54.564  -6.852  14.093  1.00 68.08  ? 143 THR C CA  1 
ATOM   9187  C C   . THR C 1 83  ? -55.338  -8.160  13.861  1.00 61.35  ? 143 THR C C   1 
ATOM   9188  O O   . THR C 1 83  ? -54.747  -9.130  13.353  1.00 68.83  ? 143 THR C O   1 
ATOM   9189  C CB  . THR C 1 83  ? -53.566  -6.994  15.249  1.00 63.57  ? 143 THR C CB  1 
ATOM   9190  O OG1 . THR C 1 83  ? -54.262  -6.989  16.493  1.00 64.22  ? 143 THR C OG1 1 
ATOM   9191  C CG2 . THR C 1 83  ? -52.515  -5.908  15.220  1.00 67.41  ? 143 THR C CG2 1 
ATOM   9192  N N   . LEU C 1 84  ? -56.615  -8.210  14.190  1.00 55.24  ? 144 LEU C N   1 
ATOM   9193  C CA  . LEU C 1 84  ? -57.387  -9.448  13.972  1.00 59.80  ? 144 LEU C CA  1 
ATOM   9194  C C   . LEU C 1 84  ? -57.641  -9.638  12.480  1.00 60.90  ? 144 LEU C C   1 
ATOM   9195  O O   . LEU C 1 84  ? -57.672  -10.808 11.999  1.00 55.87  ? 144 LEU C O   1 
ATOM   9196  C CB  . LEU C 1 84  ? -58.690  -9.356  14.751  1.00 56.37  ? 144 LEU C CB  1 
ATOM   9197  C CG  . LEU C 1 84  ? -59.450  -10.663 14.871  1.00 58.72  ? 144 LEU C CG  1 
ATOM   9198  C CD1 . LEU C 1 84  ? -58.583  -11.813 15.394  1.00 55.46  ? 144 LEU C CD1 1 
ATOM   9199  C CD2 . LEU C 1 84  ? -60.625  -10.417 15.819  1.00 65.19  ? 144 LEU C CD2 1 
ATOM   9200  N N   . ARG C 1 85  ? -57.823  -8.524  11.775  1.00 64.94  ? 145 ARG C N   1 
ATOM   9201  C CA  . ARG C 1 85  ? -58.226  -8.521  10.341  1.00 65.63  ? 145 ARG C CA  1 
ATOM   9202  C C   . ARG C 1 85  ? -57.013  -8.814  9.457   1.00 64.77  ? 145 ARG C C   1 
ATOM   9203  O O   . ARG C 1 85  ? -57.224  -9.081  8.283   1.00 69.21  ? 145 ARG C O   1 
ATOM   9204  C CB  . ARG C 1 85  ? -58.872  -7.181  9.979   1.00 68.58  ? 145 ARG C CB  1 
ATOM   9205  C CG  . ARG C 1 85  ? -60.173  -6.927  10.724  1.00 66.24  ? 145 ARG C CG  1 
ATOM   9206  C CD  . ARG C 1 85  ? -60.824  -5.650  10.279  1.00 67.04  ? 145 ARG C CD  1 
ATOM   9207  N NE  . ARG C 1 85  ? -61.966  -5.342  11.127  1.00 66.82  ? 145 ARG C NE  1 
ATOM   9208  C CZ  . ARG C 1 85  ? -62.126  -4.208  11.805  1.00 65.21  ? 145 ARG C CZ  1 
ATOM   9209  N NH1 . ARG C 1 85  ? -61.216  -3.251  11.717  1.00 67.31  ? 145 ARG C NH1 1 
ATOM   9210  N NH2 . ARG C 1 85  ? -63.210  -4.021  12.537  1.00 58.45  ? 145 ARG C NH2 1 
ATOM   9211  N N   . GLN C 1 86  ? -55.789  -8.760  9.987   1.00 66.41  ? 146 GLN C N   1 
ATOM   9212  C CA  . GLN C 1 86  ? -54.571  -9.048  9.198   1.00 62.65  ? 146 GLN C CA  1 
ATOM   9213  C C   . GLN C 1 86  ? -54.361  -10.567 9.109   1.00 57.38  ? 146 GLN C C   1 
ATOM   9214  O O   . GLN C 1 86  ? -53.674  -10.982 8.197   1.00 61.70  ? 146 GLN C O   1 
ATOM   9215  C CB  . GLN C 1 86  ? -53.368  -8.290  9.763   1.00 64.39  ? 146 GLN C CB  1 
ATOM   9216  C CG  . GLN C 1 86  ? -53.042  -7.010  9.008   1.00 67.46  ? 146 GLN C CG  1 
ATOM   9217  C CD  . GLN C 1 86  ? -53.191  -5.772  9.849   1.00 78.68  ? 146 GLN C CD  1 
ATOM   9218  O OE1 . GLN C 1 86  ? -52.764  -5.699  11.006  1.00 102.91 ? 146 GLN C OE1 1 
ATOM   9219  N NE2 . GLN C 1 86  ? -53.757  -4.754  9.234   1.00 94.75  ? 146 GLN C NE2 1 
ATOM   9220  N N   . TYR C 1 87  ? -54.934  -11.362 10.009  1.00 58.72  ? 147 TYR C N   1 
ATOM   9221  C CA  . TYR C 1 87  ? -54.881  -12.844 9.910   1.00 61.71  ? 147 TYR C CA  1 
ATOM   9222  C C   . TYR C 1 87  ? -55.669  -13.238 8.666   1.00 59.62  ? 147 TYR C C   1 
ATOM   9223  O O   . TYR C 1 87  ? -56.715  -12.613 8.354   1.00 65.28  ? 147 TYR C O   1 
ATOM   9224  C CB  . TYR C 1 87  ? -55.375  -13.534 11.194  1.00 67.81  ? 147 TYR C CB  1 
ATOM   9225  C CG  . TYR C 1 87  ? -54.452  -13.317 12.363  1.00 71.27  ? 147 TYR C CG  1 
ATOM   9226  C CD1 . TYR C 1 87  ? -53.258  -14.017 12.443  1.00 64.79  ? 147 TYR C CD1 1 
ATOM   9227  C CD2 . TYR C 1 87  ? -54.718  -12.357 13.334  1.00 66.40  ? 147 TYR C CD2 1 
ATOM   9228  C CE1 . TYR C 1 87  ? -52.351  -13.775 13.461  1.00 62.19  ? 147 TYR C CE1 1 
ATOM   9229  C CE2 . TYR C 1 87  ? -53.827  -12.122 14.371  1.00 65.51  ? 147 TYR C CE2 1 
ATOM   9230  C CZ  . TYR C 1 87  ? -52.632  -12.827 14.424  1.00 67.58  ? 147 TYR C CZ  1 
ATOM   9231  O OH  . TYR C 1 87  ? -51.711  -12.656 15.420  1.00 66.30  ? 147 TYR C OH  1 
ATOM   9232  N N   . GLN C 1 88  ? -55.209  -14.281 8.008   1.00 58.63  ? 148 GLN C N   1 
ATOM   9233  C CA  . GLN C 1 88  ? -55.800  -14.739 6.734   1.00 64.34  ? 148 GLN C CA  1 
ATOM   9234  C C   . GLN C 1 88  ? -56.958  -15.674 7.025   1.00 60.21  ? 148 GLN C C   1 
ATOM   9235  O O   . GLN C 1 88  ? -58.062  -15.378 6.591   1.00 87.23  ? 148 GLN C O   1 
ATOM   9236  C CB  . GLN C 1 88  ? -54.799  -15.496 5.867   1.00 74.70  ? 148 GLN C CB  1 
ATOM   9237  C CG  . GLN C 1 88  ? -53.368  -14.977 5.937   1.00 84.01  ? 148 GLN C CG  1 
ATOM   9238  C CD  . GLN C 1 88  ? -53.201  -13.544 5.494   1.00 85.84  ? 148 GLN C CD  1 
ATOM   9239  O OE1 . GLN C 1 88  ? -53.872  -13.071 4.573   1.00 85.53  ? 148 GLN C OE1 1 
ATOM   9240  N NE2 . GLN C 1 88  ? -52.239  -12.870 6.108   1.00 91.37  ? 148 GLN C NE2 1 
ATOM   9241  N N   . THR C 1 89  ? -56.707  -16.768 7.722   1.00 54.15  ? 149 THR C N   1 
ATOM   9242  C CA  . THR C 1 89  ? -57.727  -17.832 7.887   1.00 51.26  ? 149 THR C CA  1 
ATOM   9243  C C   . THR C 1 89  ? -58.675  -17.410 9.015   1.00 53.91  ? 149 THR C C   1 
ATOM   9244  O O   . THR C 1 89  ? -58.369  -16.536 9.829   1.00 44.60  ? 149 THR C O   1 
ATOM   9245  C CB  . THR C 1 89  ? -57.076  -19.207 8.011   1.00 48.59  ? 149 THR C CB  1 
ATOM   9246  O OG1 . THR C 1 89  ? -56.567  -19.380 9.333   1.00 54.68  ? 149 THR C OG1 1 
ATOM   9247  C CG2 . THR C 1 89  ? -55.959  -19.405 7.019   1.00 53.02  ? 149 THR C CG2 1 
ATOM   9248  N N   . PRO C 1 90  ? -59.932  -17.918 9.026   1.00 60.24  ? 150 PRO C N   1 
ATOM   9249  C CA  . PRO C 1 90  ? -60.815  -17.718 10.176  1.00 61.21  ? 150 PRO C CA  1 
ATOM   9250  C C   . PRO C 1 90  ? -60.235  -18.401 11.419  1.00 62.32  ? 150 PRO C C   1 
ATOM   9251  O O   . PRO C 1 90  ? -60.214  -17.717 12.431  1.00 71.07  ? 150 PRO C O   1 
ATOM   9252  C CB  . PRO C 1 90  ? -62.144  -18.334 9.746   1.00 61.59  ? 150 PRO C CB  1 
ATOM   9253  C CG  . PRO C 1 90  ? -62.067  -18.279 8.233   1.00 62.85  ? 150 PRO C CG  1 
ATOM   9254  C CD  . PRO C 1 90  ? -60.618  -18.589 7.907   1.00 60.53  ? 150 PRO C CD  1 
ATOM   9255  N N   . LEU C 1 91  ? -59.763  -19.664 11.305  1.00 50.32  ? 151 LEU C N   1 
ATOM   9256  C CA  . LEU C 1 91  ? -59.108  -20.410 12.420  1.00 42.45  ? 151 LEU C CA  1 
ATOM   9257  C C   . LEU C 1 91  ? -58.030  -19.545 13.098  1.00 39.24  ? 151 LEU C C   1 
ATOM   9258  O O   . LEU C 1 91  ? -57.993  -19.519 14.285  1.00 43.20  ? 151 LEU C O   1 
ATOM   9259  C CB  . LEU C 1 91  ? -58.506  -21.711 11.889  1.00 39.34  ? 151 LEU C CB  1 
ATOM   9260  C CG  . LEU C 1 91  ? -57.896  -22.629 12.945  1.00 35.52  ? 151 LEU C CG  1 
ATOM   9261  C CD1 . LEU C 1 91  ? -58.885  -22.863 14.066  1.00 38.37  ? 151 LEU C CD1 1 
ATOM   9262  C CD2 . LEU C 1 91  ? -57.496  -23.957 12.333  1.00 37.38  ? 151 LEU C CD2 1 
ATOM   9263  N N   . GLN C 1 92  ? -57.202  -18.820 12.364  1.00 44.17  ? 152 GLN C N   1 
ATOM   9264  C CA  . GLN C 1 92  ? -56.205  -17.867 12.935  1.00 47.55  ? 152 GLN C CA  1 
ATOM   9265  C C   . GLN C 1 92  ? -56.893  -16.775 13.758  1.00 43.37  ? 152 GLN C C   1 
ATOM   9266  O O   . GLN C 1 92  ? -56.324  -16.428 14.789  1.00 53.55  ? 152 GLN C O   1 
ATOM   9267  C CB  . GLN C 1 92  ? -55.323  -17.206 11.864  1.00 48.95  ? 152 GLN C CB  1 
ATOM   9268  C CG  . GLN C 1 92  ? -54.239  -18.139 11.350  1.00 52.86  ? 152 GLN C CG  1 
ATOM   9269  C CD  . GLN C 1 92  ? -53.602  -17.632 10.087  1.00 56.01  ? 152 GLN C CD  1 
ATOM   9270  O OE1 . GLN C 1 92  ? -53.814  -16.499 9.684   1.00 63.74  ? 152 GLN C OE1 1 
ATOM   9271  N NE2 . GLN C 1 92  ? -52.831  -18.489 9.443   1.00 64.49  ? 152 GLN C NE2 1 
ATOM   9272  N N   . ARG C 1 93  ? -58.046  -16.258 13.350  1.00 42.51  ? 153 ARG C N   1 
ATOM   9273  C CA  . ARG C 1 93  ? -58.774  -15.246 14.169  1.00 48.39  ? 153 ARG C CA  1 
ATOM   9274  C C   . ARG C 1 93  ? -59.424  -15.898 15.391  1.00 48.05  ? 153 ARG C C   1 
ATOM   9275  O O   . ARG C 1 93  ? -59.538  -15.180 16.425  1.00 45.55  ? 153 ARG C O   1 
ATOM   9276  C CB  . ARG C 1 93  ? -59.835  -14.510 13.369  1.00 51.83  ? 153 ARG C CB  1 
ATOM   9277  C CG  . ARG C 1 93  ? -59.267  -13.675 12.235  1.00 58.11  ? 153 ARG C CG  1 
ATOM   9278  C CD  . ARG C 1 93  ? -60.423  -13.222 11.387  1.00 58.86  ? 153 ARG C CD  1 
ATOM   9279  N NE  . ARG C 1 93  ? -60.055  -13.102 9.997   1.00 67.48  ? 153 ARG C NE  1 
ATOM   9280  C CZ  . ARG C 1 93  ? -60.185  -12.003 9.280   1.00 74.78  ? 153 ARG C CZ  1 
ATOM   9281  N NH1 . ARG C 1 93  ? -60.759  -10.925 9.800   1.00 73.88  ? 153 ARG C NH1 1 
ATOM   9282  N NH2 . ARG C 1 93  ? -59.776  -12.019 8.024   1.00 80.22  ? 153 ARG C NH2 1 
ATOM   9283  N N   . TYR C 1 94  ? -59.818  -17.186 15.299  1.00 47.89  ? 154 TYR C N   1 
ATOM   9284  C CA  . TYR C 1 94  ? -60.323  -17.986 16.452  1.00 45.85  ? 154 TYR C CA  1 
ATOM   9285  C C   . TYR C 1 94  ? -59.225  -18.119 17.500  1.00 45.09  ? 154 TYR C C   1 
ATOM   9286  O O   . TYR C 1 94  ? -59.518  -17.994 18.704  1.00 48.66  ? 154 TYR C O   1 
ATOM   9287  C CB  . TYR C 1 94  ? -60.803  -19.393 16.058  1.00 48.81  ? 154 TYR C CB  1 
ATOM   9288  C CG  . TYR C 1 94  ? -61.103  -20.322 17.219  1.00 48.34  ? 154 TYR C CG  1 
ATOM   9289  C CD1 . TYR C 1 94  ? -60.146  -21.202 17.680  1.00 45.56  ? 154 TYR C CD1 1 
ATOM   9290  C CD2 . TYR C 1 94  ? -62.326  -20.306 17.869  1.00 44.95  ? 154 TYR C CD2 1 
ATOM   9291  C CE1 . TYR C 1 94  ? -60.401  -22.037 18.749  1.00 51.51  ? 154 TYR C CE1 1 
ATOM   9292  C CE2 . TYR C 1 94  ? -62.595  -21.136 18.938  1.00 48.30  ? 154 TYR C CE2 1 
ATOM   9293  C CZ  . TYR C 1 94  ? -61.630  -22.015 19.384  1.00 51.41  ? 154 TYR C CZ  1 
ATOM   9294  O OH  . TYR C 1 94  ? -61.863  -22.845 20.456  1.00 53.46  ? 154 TYR C OH  1 
ATOM   9295  N N   . ILE C 1 95  ? -58.005  -18.416 17.056  1.00 45.98  ? 155 ILE C N   1 
ATOM   9296  C CA  . ILE C 1 95  ? -56.854  -18.660 17.962  1.00 46.67  ? 155 ILE C CA  1 
ATOM   9297  C C   . ILE C 1 95  ? -56.532  -17.340 18.645  1.00 44.43  ? 155 ILE C C   1 
ATOM   9298  O O   . ILE C 1 95  ? -56.293  -17.379 19.854  1.00 44.82  ? 155 ILE C O   1 
ATOM   9299  C CB  . ILE C 1 95  ? -55.667  -19.302 17.221  1.00 51.57  ? 155 ILE C CB  1 
ATOM   9300  C CG1 . ILE C 1 95  ? -56.051  -20.698 16.705  1.00 52.48  ? 155 ILE C CG1 1 
ATOM   9301  C CG2 . ILE C 1 95  ? -54.445  -19.389 18.120  1.00 56.31  ? 155 ILE C CG2 1 
ATOM   9302  C CD1 . ILE C 1 95  ? -55.030  -21.290 15.769  1.00 59.16  ? 155 ILE C CD1 1 
ATOM   9303  N N   . ALA C 1 96  ? -56.574  -16.219 17.921  1.00 48.04  ? 156 ALA C N   1 
ATOM   9304  C CA  . ALA C 1 96  ? -56.254  -14.881 18.479  1.00 49.38  ? 156 ALA C CA  1 
ATOM   9305  C C   . ALA C 1 96  ? -57.348  -14.467 19.463  1.00 50.06  ? 156 ALA C C   1 
ATOM   9306  O O   . ALA C 1 96  ? -57.034  -13.769 20.410  1.00 65.65  ? 156 ALA C O   1 
ATOM   9307  C CB  . ALA C 1 96  ? -56.053  -13.858 17.390  1.00 51.91  ? 156 ALA C CB  1 
ATOM   9308  N N   . MET C 1 97  ? -58.582  -14.914 19.252  1.00 52.39  ? 157 MET C N   1 
ATOM   9309  C CA  . MET C 1 97  ? -59.736  -14.589 20.138  1.00 53.13  ? 157 MET C CA  1 
ATOM   9310  C C   . MET C 1 97  ? -59.590  -15.388 21.442  1.00 54.62  ? 157 MET C C   1 
ATOM   9311  O O   . MET C 1 97  ? -59.690  -14.766 22.498  1.00 64.57  ? 157 MET C O   1 
ATOM   9312  C CB  . MET C 1 97  ? -61.074  -14.887 19.453  1.00 52.22  ? 157 MET C CB  1 
ATOM   9313  C CG  . MET C 1 97  ? -61.513  -13.817 18.441  1.00 55.25  ? 157 MET C CG  1 
ATOM   9314  S SD  . MET C 1 97  ? -61.784  -12.112 19.092  1.00 57.94  ? 157 MET C SD  1 
ATOM   9315  C CE  . MET C 1 97  ? -63.119  -12.407 20.247  1.00 55.83  ? 157 MET C CE  1 
ATOM   9316  N N   . MET C 1 98  ? -59.285  -16.693 21.373  1.00 55.52  ? 158 MET C N   1 
ATOM   9317  C CA  . MET C 1 98  ? -59.161  -17.593 22.558  1.00 57.00  ? 158 MET C CA  1 
ATOM   9318  C C   . MET C 1 98  ? -57.952  -17.170 23.395  1.00 59.19  ? 158 MET C C   1 
ATOM   9319  O O   . MET C 1 98  ? -58.085  -17.095 24.622  1.00 71.21  ? 158 MET C O   1 
ATOM   9320  C CB  . MET C 1 98  ? -59.043  -19.070 22.160  1.00 63.81  ? 158 MET C CB  1 
ATOM   9321  C CG  . MET C 1 98  ? -60.329  -19.624 21.539  1.00 66.24  ? 158 MET C CG  1 
ATOM   9322  S SD  . MET C 1 98  ? -61.818  -19.327 22.515  1.00 75.65  ? 158 MET C SD  1 
ATOM   9323  C CE  . MET C 1 98  ? -62.883  -18.494 21.336  1.00 71.84  ? 158 MET C CE  1 
ATOM   9324  N N   . ASN C 1 99  ? -56.837  -16.840 22.750  1.00 63.60  ? 159 ASN C N   1 
ATOM   9325  C CA  . ASN C 1 99  ? -55.649  -16.207 23.387  1.00 75.71  ? 159 ASN C CA  1 
ATOM   9326  C C   . ASN C 1 99  ? -56.053  -14.960 24.210  1.00 68.56  ? 159 ASN C C   1 
ATOM   9327  O O   . ASN C 1 99  ? -55.630  -14.886 25.374  1.00 65.23  ? 159 ASN C O   1 
ATOM   9328  C CB  . ASN C 1 99  ? -54.582  -15.855 22.344  1.00 84.01  ? 159 ASN C CB  1 
ATOM   9329  C CG  . ASN C 1 99  ? -53.179  -15.865 22.900  1.00 86.11  ? 159 ASN C CG  1 
ATOM   9330  O OD1 . ASN C 1 99  ? -52.602  -14.802 23.158  1.00 78.69  ? 159 ASN C OD1 1 
ATOM   9331  N ND2 . ASN C 1 99  ? -52.623  -17.063 23.055  1.00 85.41  ? 159 ASN C ND2 1 
ATOM   9332  N N   . LEU C 1 100 ? -56.822  -14.010 23.652  1.00 51.84  ? 160 LEU C N   1 
ATOM   9333  C CA  . LEU C 1 100 ? -57.258  -12.770 24.353  1.00 43.66  ? 160 LEU C CA  1 
ATOM   9334  C C   . LEU C 1 100 ? -58.169  -13.118 25.537  1.00 44.44  ? 160 LEU C C   1 
ATOM   9335  O O   . LEU C 1 100 ? -57.982  -12.549 26.642  1.00 41.51  ? 160 LEU C O   1 
ATOM   9336  C CB  . LEU C 1 100 ? -57.995  -11.865 23.370  1.00 42.92  ? 160 LEU C CB  1 
ATOM   9337  C CG  . LEU C 1 100 ? -58.535  -10.553 23.939  1.00 43.76  ? 160 LEU C CG  1 
ATOM   9338  C CD1 . LEU C 1 100 ? -57.472  -9.631  24.526  1.00 37.79  ? 160 LEU C CD1 1 
ATOM   9339  C CD2 . LEU C 1 100 ? -59.247  -9.808  22.833  1.00 48.58  ? 160 LEU C CD2 1 
ATOM   9340  N N   . GLN C 1 101 ? -59.125  -14.028 25.337  1.00 50.47  ? 161 GLN C N   1 
ATOM   9341  C CA  . GLN C 1 101 ? -60.015  -14.519 26.425  1.00 51.39  ? 161 GLN C CA  1 
ATOM   9342  C C   . GLN C 1 101 ? -59.156  -14.876 27.636  1.00 52.42  ? 161 GLN C C   1 
ATOM   9343  O O   . GLN C 1 101 ? -59.577  -14.565 28.781  1.00 54.40  ? 161 GLN C O   1 
ATOM   9344  C CB  . GLN C 1 101 ? -60.846  -15.729 26.019  1.00 54.69  ? 161 GLN C CB  1 
ATOM   9345  C CG  . GLN C 1 101 ? -61.916  -16.051 27.054  1.00 56.77  ? 161 GLN C CG  1 
ATOM   9346  C CD  . GLN C 1 101 ? -62.675  -17.321 26.762  1.00 63.92  ? 161 GLN C CD  1 
ATOM   9347  O OE1 . GLN C 1 101 ? -62.097  -18.351 26.422  1.00 73.03  ? 161 GLN C OE1 1 
ATOM   9348  N NE2 . GLN C 1 101 ? -63.978  -17.293 26.974  1.00 66.56  ? 161 GLN C NE2 1 
ATOM   9349  N N   . GLU C 1 102 ? -57.993  -15.496 27.384  1.00 52.35  ? 162 GLU C N   1 
ATOM   9350  C CA  . GLU C 1 102 ? -57.096  -16.085 28.414  1.00 53.27  ? 162 GLU C CA  1 
ATOM   9351  C C   . GLU C 1 102 ? -55.928  -15.163 28.743  1.00 46.54  ? 162 GLU C C   1 
ATOM   9352  O O   . GLU C 1 102 ? -54.939  -15.692 29.232  1.00 48.82  ? 162 GLU C O   1 
ATOM   9353  C CB  . GLU C 1 102 ? -56.603  -17.468 27.965  1.00 58.69  ? 162 GLU C CB  1 
ATOM   9354  C CG  . GLU C 1 102 ? -57.730  -18.459 27.720  1.00 64.15  ? 162 GLU C CG  1 
ATOM   9355  C CD  . GLU C 1 102 ? -58.651  -18.736 28.907  1.00 74.21  ? 162 GLU C CD  1 
ATOM   9356  O OE1 . GLU C 1 102 ? -59.905  -18.491 28.781  1.00 63.79  ? 162 GLU C OE1 1 
ATOM   9357  O OE2 . GLU C 1 102 ? -58.111  -19.173 29.976  1.00 86.39  ? 162 GLU C OE2 1 
ATOM   9358  N N   . THR C 1 103 ? -56.030  -13.855 28.515  1.00 46.89  ? 163 THR C N   1 
ATOM   9359  C CA  . THR C 1 103 ? -54.987  -12.868 28.932  1.00 51.35  ? 163 THR C CA  1 
ATOM   9360  C C   . THR C 1 103 ? -55.623  -11.598 29.511  1.00 49.78  ? 163 THR C C   1 
ATOM   9361  O O   . THR C 1 103 ? -55.019  -11.039 30.461  1.00 42.95  ? 163 THR C O   1 
ATOM   9362  C CB  . THR C 1 103 ? -53.999  -12.510 27.804  1.00 53.81  ? 163 THR C CB  1 
ATOM   9363  O OG1 . THR C 1 103 ? -54.542  -11.592 26.863  1.00 54.44  ? 163 THR C OG1 1 
ATOM   9364  C CG2 . THR C 1 103 ? -53.508  -13.712 27.033  1.00 53.19  ? 163 THR C CG2 1 
ATOM   9365  N N   . ASP C 1 104 ? -56.745  -11.161 28.929  1.00 50.45  ? 164 ASP C N   1 
ATOM   9366  C CA  . ASP C 1 104 ? -57.585  -10.036 29.405  1.00 52.34  ? 164 ASP C CA  1 
ATOM   9367  C C   . ASP C 1 104 ? -59.052  -10.380 29.083  1.00 56.04  ? 164 ASP C C   1 
ATOM   9368  O O   . ASP C 1 104 ? -59.502  -10.145 27.914  1.00 58.04  ? 164 ASP C O   1 
ATOM   9369  C CB  . ASP C 1 104 ? -57.112  -8.720  28.783  1.00 48.58  ? 164 ASP C CB  1 
ATOM   9370  C CG  . ASP C 1 104 ? -57.858  -7.478  29.261  1.00 47.18  ? 164 ASP C CG  1 
ATOM   9371  O OD1 . ASP C 1 104 ? -58.910  -7.600  29.950  1.00 38.93  ? 164 ASP C OD1 1 
ATOM   9372  O OD2 . ASP C 1 104 ? -57.395  -6.394  28.914  1.00 48.17  ? 164 ASP C OD2 1 
ATOM   9373  N N   . GLU C 1 105 ? -59.773  -10.902 30.077  1.00 56.19  ? 165 GLU C N   1 
ATOM   9374  C CA  . GLU C 1 105 ? -61.138  -11.458 29.874  1.00 63.25  ? 165 GLU C CA  1 
ATOM   9375  C C   . GLU C 1 105 ? -62.098  -10.281 29.711  1.00 58.45  ? 165 GLU C C   1 
ATOM   9376  O O   . GLU C 1 105 ? -63.009  -10.385 28.883  1.00 58.91  ? 165 GLU C O   1 
ATOM   9377  C CB  . GLU C 1 105 ? -61.517  -12.493 30.935  1.00 67.44  ? 165 GLU C CB  1 
ATOM   9378  C CG  . GLU C 1 105 ? -61.818  -11.895 32.294  1.00 78.98  ? 165 GLU C CG  1 
ATOM   9379  C CD  . GLU C 1 105 ? -62.864  -12.596 33.144  1.00 81.61  ? 165 GLU C CD  1 
ATOM   9380  O OE1 . GLU C 1 105 ? -63.575  -11.864 33.875  1.00 80.36  ? 165 GLU C OE1 1 
ATOM   9381  O OE2 . GLU C 1 105 ? -62.918  -13.859 33.138  1.00 74.32  ? 165 GLU C OE2 1 
ATOM   9382  N N   . ARG C 1 106 ? -61.879  -9.178  30.410  1.00 52.18  ? 166 ARG C N   1 
ATOM   9383  C CA  . ARG C 1 106 ? -62.772  -8.000  30.267  1.00 60.79  ? 166 ARG C CA  1 
ATOM   9384  C C   . ARG C 1 106 ? -62.650  -7.371  28.872  1.00 60.90  ? 166 ARG C C   1 
ATOM   9385  O O   . ARG C 1 106 ? -63.679  -6.974  28.300  1.00 61.07  ? 166 ARG C O   1 
ATOM   9386  C CB  . ARG C 1 106 ? -62.449  -7.000  31.366  1.00 72.64  ? 166 ARG C CB  1 
ATOM   9387  C CG  . ARG C 1 106 ? -62.784  -7.599  32.725  1.00 71.56  ? 166 ARG C CG  1 
ATOM   9388  C CD  . ARG C 1 106 ? -62.967  -6.490  33.708  1.00 76.45  ? 166 ARG C CD  1 
ATOM   9389  N NE  . ARG C 1 106 ? -64.320  -6.410  34.215  1.00 74.90  ? 166 ARG C NE  1 
ATOM   9390  C CZ  . ARG C 1 106 ? -64.718  -6.951  35.365  1.00 83.88  ? 166 ARG C CZ  1 
ATOM   9391  N NH1 . ARG C 1 106 ? -63.888  -7.690  36.101  1.00 81.92  ? 166 ARG C NH1 1 
ATOM   9392  N NH2 . ARG C 1 106 ? -65.974  -6.782  35.736  1.00 78.11  ? 166 ARG C NH2 1 
ATOM   9393  N N   . LEU C 1 107 ? -61.444  -7.267  28.318  1.00 66.13  ? 167 LEU C N   1 
ATOM   9394  C CA  . LEU C 1 107 ? -61.245  -6.734  26.936  1.00 52.73  ? 167 LEU C CA  1 
ATOM   9395  C C   . LEU C 1 107 ? -61.872  -7.695  25.920  1.00 45.54  ? 167 LEU C C   1 
ATOM   9396  O O   . LEU C 1 107 ? -62.542  -7.231  25.013  1.00 37.25  ? 167 LEU C O   1 
ATOM   9397  C CB  . LEU C 1 107 ? -59.751  -6.541  26.670  1.00 50.54  ? 167 LEU C CB  1 
ATOM   9398  C CG  . LEU C 1 107 ? -59.416  -6.040  25.272  1.00 53.59  ? 167 LEU C CG  1 
ATOM   9399  C CD1 . LEU C 1 107 ? -60.119  -4.703  25.014  1.00 56.82  ? 167 LEU C CD1 1 
ATOM   9400  C CD2 . LEU C 1 107 ? -57.907  -5.928  25.061  1.00 45.65  ? 167 LEU C CD2 1 
ATOM   9401  N N   . PHE C 1 108 ? -61.673  -8.998  26.105  1.00 48.31  ? 168 PHE C N   1 
ATOM   9402  C CA  . PHE C 1 108 ? -62.236  -10.079 25.250  1.00 41.68  ? 168 PHE C CA  1 
ATOM   9403  C C   . PHE C 1 108 ? -63.746  -9.960  25.194  1.00 41.58  ? 168 PHE C C   1 
ATOM   9404  O O   . PHE C 1 108 ? -64.266  -10.045 24.081  1.00 48.18  ? 168 PHE C O   1 
ATOM   9405  C CB  . PHE C 1 108 ? -61.902  -11.455 25.801  1.00 42.71  ? 168 PHE C CB  1 
ATOM   9406  C CG  . PHE C 1 108 ? -62.685  -12.582 25.207  1.00 38.95  ? 168 PHE C CG  1 
ATOM   9407  C CD1 . PHE C 1 108 ? -62.262  -13.178 24.048  1.00 41.84  ? 168 PHE C CD1 1 
ATOM   9408  C CD2 . PHE C 1 108 ? -63.809  -13.070 25.825  1.00 39.43  ? 168 PHE C CD2 1 
ATOM   9409  C CE1 . PHE C 1 108 ? -62.948  -14.258 23.499  1.00 47.00  ? 168 PHE C CE1 1 
ATOM   9410  C CE2 . PHE C 1 108 ? -64.503  -14.131 25.259  1.00 47.99  ? 168 PHE C CE2 1 
ATOM   9411  C CZ  . PHE C 1 108 ? -64.071  -14.740 24.103  1.00 43.05  ? 168 PHE C CZ  1 
ATOM   9412  N N   . TYR C 1 109 ? -64.427  -9.804  26.332  1.00 37.77  ? 169 TYR C N   1 
ATOM   9413  C CA  . TYR C 1 109 ? -65.911  -9.751  26.334  1.00 43.87  ? 169 TYR C CA  1 
ATOM   9414  C C   . TYR C 1 109 ? -66.356  -8.386  25.781  1.00 45.75  ? 169 TYR C C   1 
ATOM   9415  O O   . TYR C 1 109 ? -67.189  -8.392  24.860  1.00 48.77  ? 169 TYR C O   1 
ATOM   9416  C CB  . TYR C 1 109 ? -66.512  -10.143 27.682  1.00 41.79  ? 169 TYR C CB  1 
ATOM   9417  C CG  . TYR C 1 109 ? -66.402  -11.613 27.963  1.00 44.86  ? 169 TYR C CG  1 
ATOM   9418  C CD1 . TYR C 1 109 ? -67.048  -12.532 27.168  1.00 44.51  ? 169 TYR C CD1 1 
ATOM   9419  C CD2 . TYR C 1 109 ? -65.617  -12.097 28.999  1.00 49.15  ? 169 TYR C CD2 1 
ATOM   9420  C CE1 . TYR C 1 109 ? -66.943  -13.895 27.409  1.00 48.12  ? 169 TYR C CE1 1 
ATOM   9421  C CE2 . TYR C 1 109 ? -65.490  -13.457 29.245  1.00 53.06  ? 169 TYR C CE2 1 
ATOM   9422  C CZ  . TYR C 1 109 ? -66.156  -14.368 28.446  1.00 51.24  ? 169 TYR C CZ  1 
ATOM   9423  O OH  . TYR C 1 109 ? -66.022  -15.710 28.663  1.00 46.01  ? 169 TYR C OH  1 
ATOM   9424  N N   . LYS C 1 110 ? -65.776  -7.269  26.227  1.00 46.24  ? 170 LYS C N   1 
ATOM   9425  C CA  . LYS C 1 110 ? -66.209  -5.920  25.764  1.00 49.29  ? 170 LYS C CA  1 
ATOM   9426  C C   . LYS C 1 110 ? -66.011  -5.806  24.243  1.00 49.93  ? 170 LYS C C   1 
ATOM   9427  O O   . LYS C 1 110 ? -66.872  -5.209  23.561  1.00 41.68  ? 170 LYS C O   1 
ATOM   9428  C CB  . LYS C 1 110 ? -65.462  -4.829  26.527  1.00 54.06  ? 170 LYS C CB  1 
ATOM   9429  C CG  . LYS C 1 110 ? -66.287  -3.591  26.839  1.00 56.85  ? 170 LYS C CG  1 
ATOM   9430  C CD  . LYS C 1 110 ? -66.163  -2.572  25.761  1.00 58.94  ? 170 LYS C CD  1 
ATOM   9431  C CE  . LYS C 1 110 ? -66.728  -1.230  26.151  1.00 68.55  ? 170 LYS C CE  1 
ATOM   9432  N NZ  . LYS C 1 110 ? -65.836  -0.117  25.713  1.00 80.95  ? 170 LYS C NZ  1 
ATOM   9433  N N   . LEU C 1 111 ? -64.955  -6.426  23.714  1.00 54.59  ? 171 LEU C N   1 
ATOM   9434  C CA  . LEU C 1 111 ? -64.681  -6.462  22.252  1.00 58.22  ? 171 LEU C CA  1 
ATOM   9435  C C   . LEU C 1 111 ? -65.769  -7.304  21.576  1.00 60.96  ? 171 LEU C C   1 
ATOM   9436  O O   . LEU C 1 111 ? -66.443  -6.759  20.689  1.00 54.01  ? 171 LEU C O   1 
ATOM   9437  C CB  . LEU C 1 111 ? -63.276  -7.028  22.029  1.00 62.35  ? 171 LEU C CB  1 
ATOM   9438  C CG  . LEU C 1 111 ? -62.859  -7.347  20.591  1.00 60.39  ? 171 LEU C CG  1 
ATOM   9439  C CD1 . LEU C 1 111 ? -61.587  -6.579  20.246  1.00 65.10  ? 171 LEU C CD1 1 
ATOM   9440  C CD2 . LEU C 1 111 ? -62.667  -8.860  20.374  1.00 47.06  ? 171 LEU C CD2 1 
ATOM   9441  N N   . LEU C 1 112 ? -65.944  -8.560  22.010  1.00 57.61  ? 172 LEU C N   1 
ATOM   9442  C CA  . LEU C 1 112 ? -66.931  -9.513  21.434  1.00 56.59  ? 172 LEU C CA  1 
ATOM   9443  C C   . LEU C 1 112 ? -68.317  -8.862  21.347  1.00 50.60  ? 172 LEU C C   1 
ATOM   9444  O O   . LEU C 1 112 ? -68.908  -8.923  20.291  1.00 49.78  ? 172 LEU C O   1 
ATOM   9445  C CB  . LEU C 1 112 ? -66.975  -10.801 22.265  1.00 53.00  ? 172 LEU C CB  1 
ATOM   9446  C CG  . LEU C 1 112 ? -67.876  -11.877 21.681  1.00 48.36  ? 172 LEU C CG  1 
ATOM   9447  C CD1 . LEU C 1 112 ? -67.400  -12.236 20.286  1.00 47.68  ? 172 LEU C CD1 1 
ATOM   9448  C CD2 . LEU C 1 112 ? -67.910  -13.111 22.553  1.00 49.60  ? 172 LEU C CD2 1 
ATOM   9449  N N   . ILE C 1 113 ? -68.805  -8.245  22.414  1.00 50.96  ? 173 ILE C N   1 
ATOM   9450  C CA  . ILE C 1 113 ? -70.140  -7.567  22.439  1.00 57.11  ? 173 ILE C CA  1 
ATOM   9451  C C   . ILE C 1 113 ? -70.157  -6.460  21.380  1.00 54.62  ? 173 ILE C C   1 
ATOM   9452  O O   . ILE C 1 113 ? -70.993  -6.534  20.481  1.00 52.43  ? 173 ILE C O   1 
ATOM   9453  C CB  . ILE C 1 113 ? -70.496  -7.049  23.857  1.00 62.87  ? 173 ILE C CB  1 
ATOM   9454  C CG1 . ILE C 1 113 ? -70.592  -8.227  24.835  1.00 64.49  ? 173 ILE C CG1 1 
ATOM   9455  C CG2 . ILE C 1 113 ? -71.780  -6.224  23.842  1.00 58.38  ? 173 ILE C CG2 1 
ATOM   9456  C CD1 . ILE C 1 113 ? -70.610  -7.863  26.278  1.00 68.77  ? 173 ILE C CD1 1 
ATOM   9457  N N   . ASP C 1 114 ? -69.244  -5.489  21.469  1.00 56.69  ? 174 ASP C N   1 
ATOM   9458  C CA  . ASP C 1 114 ? -69.248  -4.271  20.601  1.00 58.39  ? 174 ASP C CA  1 
ATOM   9459  C C   . ASP C 1 114 ? -69.073  -4.637  19.123  1.00 56.98  ? 174 ASP C C   1 
ATOM   9460  O O   . ASP C 1 114 ? -69.299  -3.758  18.299  1.00 66.81  ? 174 ASP C O   1 
ATOM   9461  C CB  . ASP C 1 114 ? -68.167  -3.272  21.011  1.00 56.78  ? 174 ASP C CB  1 
ATOM   9462  C CG  . ASP C 1 114 ? -68.399  -2.711  22.411  1.00 62.31  ? 174 ASP C CG  1 
ATOM   9463  O OD1 . ASP C 1 114 ? -69.423  -3.096  23.043  1.00 56.63  ? 174 ASP C OD1 1 
ATOM   9464  O OD2 . ASP C 1 114 ? -67.555  -1.900  22.877  1.00 56.85  ? 174 ASP C OD2 1 
ATOM   9465  N N   . ASN C 1 115 ? -68.664  -5.866  18.805  1.00 57.18  ? 175 ASN C N   1 
ATOM   9466  C CA  . ASN C 1 115 ? -68.331  -6.316  17.421  1.00 58.49  ? 175 ASN C CA  1 
ATOM   9467  C C   . ASN C 1 115 ? -68.987  -7.681  17.164  1.00 58.36  ? 175 ASN C C   1 
ATOM   9468  O O   . ASN C 1 115 ? -68.416  -8.475  16.427  1.00 59.60  ? 175 ASN C O   1 
ATOM   9469  C CB  . ASN C 1 115 ? -66.809  -6.341  17.190  1.00 56.77  ? 175 ASN C CB  1 
ATOM   9470  C CG  . ASN C 1 115 ? -66.181  -4.965  17.275  1.00 63.80  ? 175 ASN C CG  1 
ATOM   9471  O OD1 . ASN C 1 115 ? -66.213  -4.197  16.322  1.00 67.74  ? 175 ASN C OD1 1 
ATOM   9472  N ND2 . ASN C 1 115 ? -65.629  -4.625  18.424  1.00 67.48  ? 175 ASN C ND2 1 
ATOM   9473  N N   . VAL C 1 116 ? -70.156  -7.934  17.748  1.00 59.48  ? 176 VAL C N   1 
ATOM   9474  C CA  . VAL C 1 116 ? -70.736  -9.306  17.886  1.00 58.98  ? 176 VAL C CA  1 
ATOM   9475  C C   . VAL C 1 116 ? -71.083  -9.900  16.516  1.00 58.76  ? 176 VAL C C   1 
ATOM   9476  O O   . VAL C 1 116 ? -70.920  -11.127 16.370  1.00 63.67  ? 176 VAL C O   1 
ATOM   9477  C CB  . VAL C 1 116 ? -71.946  -9.331  18.841  1.00 53.80  ? 176 VAL C CB  1 
ATOM   9478  C CG1 . VAL C 1 116 ? -72.974  -8.280  18.495  1.00 50.35  ? 176 VAL C CG1 1 
ATOM   9479  C CG2 . VAL C 1 116 ? -72.557  -10.721 18.904  1.00 57.15  ? 176 VAL C CG2 1 
ATOM   9480  N N   . VAL C 1 117 ? -71.561  -9.084  15.576  1.00 60.30  ? 177 VAL C N   1 
ATOM   9481  C CA  . VAL C 1 117 ? -72.008  -9.544  14.228  1.00 59.78  ? 177 VAL C CA  1 
ATOM   9482  C C   . VAL C 1 117 ? -70.774  -9.996  13.431  1.00 70.41  ? 177 VAL C C   1 
ATOM   9483  O O   . VAL C 1 117 ? -70.868  -11.054 12.743  1.00 77.46  ? 177 VAL C O   1 
ATOM   9484  C CB  . VAL C 1 117 ? -72.779  -8.429  13.484  1.00 50.61  ? 177 VAL C CB  1 
ATOM   9485  C CG1 . VAL C 1 117 ? -73.015  -8.761  12.022  1.00 42.86  ? 177 VAL C CG1 1 
ATOM   9486  C CG2 . VAL C 1 117 ? -74.088  -8.083  14.153  1.00 44.92  ? 177 VAL C CG2 1 
ATOM   9487  N N   . GLU C 1 118 ? -69.678  -9.218  13.518  1.00 74.41  ? 178 GLU C N   1 
ATOM   9488  C CA  . GLU C 1 118 ? -68.411  -9.414  12.748  1.00 69.68  ? 178 GLU C CA  1 
ATOM   9489  C C   . GLU C 1 118 ? -67.632  -10.619 13.302  1.00 64.93  ? 178 GLU C C   1 
ATOM   9490  O O   . GLU C 1 118 ? -67.064  -11.346 12.485  1.00 69.64  ? 178 GLU C O   1 
ATOM   9491  C CB  . GLU C 1 118 ? -67.552  -8.151  12.782  1.00 61.52  ? 178 GLU C CB  1 
ATOM   9492  C CG  . GLU C 1 118 ? -66.276  -8.281  11.981  1.00 69.06  ? 178 GLU C CG  1 
ATOM   9493  C CD  . GLU C 1 118 ? -65.497  -6.989  11.763  1.00 81.78  ? 178 GLU C CD  1 
ATOM   9494  O OE1 . GLU C 1 118 ? -65.971  -5.918  12.247  1.00 79.55  ? 178 GLU C OE1 1 
ATOM   9495  O OE2 . GLU C 1 118 ? -64.426  -7.058  11.097  1.00 79.55  ? 178 GLU C OE2 1 
ATOM   9496  N N   . LEU C 1 119 ? -67.657  -10.832 14.623  1.00 57.86  ? 179 LEU C N   1 
ATOM   9497  C CA  . LEU C 1 119 ? -66.751  -11.744 15.365  1.00 58.07  ? 179 LEU C CA  1 
ATOM   9498  C C   . LEU C 1 119 ? -67.424  -13.089 15.640  1.00 60.34  ? 179 LEU C C   1 
ATOM   9499  O O   . LEU C 1 119 ? -66.716  -14.072 15.908  1.00 59.66  ? 179 LEU C O   1 
ATOM   9500  C CB  . LEU C 1 119 ? -66.331  -11.088 16.689  1.00 53.10  ? 179 LEU C CB  1 
ATOM   9501  C CG  . LEU C 1 119 ? -65.325  -9.937  16.580  1.00 51.64  ? 179 LEU C CG  1 
ATOM   9502  C CD1 . LEU C 1 119 ? -64.805  -9.546  17.947  1.00 47.14  ? 179 LEU C CD1 1 
ATOM   9503  C CD2 . LEU C 1 119 ? -64.149  -10.265 15.667  1.00 51.91  ? 179 LEU C CD2 1 
ATOM   9504  N N   . LEU C 1 120 ? -68.746  -13.136 15.635  1.00 63.39  ? 180 LEU C N   1 
ATOM   9505  C CA  . LEU C 1 120 ? -69.483  -14.327 16.117  1.00 61.92  ? 180 LEU C CA  1 
ATOM   9506  C C   . LEU C 1 120 ? -69.152  -15.550 15.256  1.00 58.36  ? 180 LEU C C   1 
ATOM   9507  O O   . LEU C 1 120 ? -69.094  -16.680 15.750  1.00 42.77  ? 180 LEU C O   1 
ATOM   9508  C CB  . LEU C 1 120 ? -70.977  -14.005 16.116  1.00 59.89  ? 180 LEU C CB  1 
ATOM   9509  C CG  . LEU C 1 120 ? -71.849  -14.997 16.868  1.00 68.77  ? 180 LEU C CG  1 
ATOM   9510  C CD1 . LEU C 1 120 ? -71.291  -15.236 18.263  1.00 70.14  ? 180 LEU C CD1 1 
ATOM   9511  C CD2 . LEU C 1 120 ? -73.290  -14.475 16.918  1.00 76.23  ? 180 LEU C CD2 1 
ATOM   9512  N N   . PRO C 1 121 ? -68.964  -15.387 13.925  1.00 57.70  ? 181 PRO C N   1 
ATOM   9513  C CA  . PRO C 1 121 ? -68.676  -16.548 13.074  1.00 60.19  ? 181 PRO C CA  1 
ATOM   9514  C C   . PRO C 1 121 ? -67.287  -17.161 13.348  1.00 59.38  ? 181 PRO C C   1 
ATOM   9515  O O   . PRO C 1 121 ? -67.036  -18.287 12.915  1.00 40.56  ? 181 PRO C O   1 
ATOM   9516  C CB  . PRO C 1 121 ? -68.788  -15.995 11.639  1.00 58.27  ? 181 PRO C CB  1 
ATOM   9517  C CG  . PRO C 1 121 ? -69.478  -14.627 11.782  1.00 54.64  ? 181 PRO C CG  1 
ATOM   9518  C CD  . PRO C 1 121 ? -69.119  -14.133 13.161  1.00 52.79  ? 181 PRO C CD  1 
ATOM   9519  N N   . PHE C 1 122 ? -66.424  -16.425 14.067  1.00 62.79  ? 182 PHE C N   1 
ATOM   9520  C CA  . PHE C 1 122 ? -65.010  -16.797 14.351  1.00 56.55  ? 182 PHE C CA  1 
ATOM   9521  C C   . PHE C 1 122 ? -64.909  -17.527 15.692  1.00 58.31  ? 182 PHE C C   1 
ATOM   9522  O O   . PHE C 1 122 ? -64.212  -18.557 15.710  1.00 63.80  ? 182 PHE C O   1 
ATOM   9523  C CB  . PHE C 1 122 ? -64.122  -15.554 14.292  1.00 49.92  ? 182 PHE C CB  1 
ATOM   9524  C CG  . PHE C 1 122 ? -64.100  -14.895 12.934  1.00 51.70  ? 182 PHE C CG  1 
ATOM   9525  C CD1 . PHE C 1 122 ? -63.818  -15.634 11.795  1.00 52.22  ? 182 PHE C CD1 1 
ATOM   9526  C CD2 . PHE C 1 122 ? -64.322  -13.534 12.796  1.00 51.15  ? 182 PHE C CD2 1 
ATOM   9527  C CE1 . PHE C 1 122 ? -63.754  -15.015 10.556  1.00 53.65  ? 182 PHE C CE1 1 
ATOM   9528  C CE2 . PHE C 1 122 ? -64.286  -12.924 11.550  1.00 50.92  ? 182 PHE C CE2 1 
ATOM   9529  C CZ  . PHE C 1 122 ? -63.991  -13.662 10.434  1.00 51.00  ? 182 PHE C CZ  1 
ATOM   9530  N N   . VAL C 1 123 ? -65.616  -17.066 16.737  1.00 50.41  ? 183 VAL C N   1 
ATOM   9531  C CA  . VAL C 1 123 ? -65.646  -17.707 18.087  1.00 46.20  ? 183 VAL C CA  1 
ATOM   9532  C C   . VAL C 1 123 ? -66.679  -18.839 18.152  1.00 42.88  ? 183 VAL C C   1 
ATOM   9533  O O   . VAL C 1 123 ? -66.498  -19.732 18.977  1.00 44.55  ? 183 VAL C O   1 
ATOM   9534  C CB  . VAL C 1 123 ? -65.877  -16.653 19.181  1.00 48.94  ? 183 VAL C CB  1 
ATOM   9535  C CG1 . VAL C 1 123 ? -64.733  -15.664 19.221  1.00 61.51  ? 183 VAL C CG1 1 
ATOM   9536  C CG2 . VAL C 1 123 ? -67.180  -15.907 19.024  1.00 47.07  ? 183 VAL C CG2 1 
ATOM   9537  N N   . TYR C 1 124 ? -67.731  -18.754 17.333  1.00 52.67  ? 184 TYR C N   1 
ATOM   9538  C CA  . TYR C 1 124 ? -68.936  -19.637 17.284  1.00 58.01  ? 184 TYR C CA  1 
ATOM   9539  C C   . TYR C 1 124 ? -69.054  -20.232 15.875  1.00 51.39  ? 184 TYR C C   1 
ATOM   9540  O O   . TYR C 1 124 ? -68.081  -20.092 15.098  1.00 53.51  ? 184 TYR C O   1 
ATOM   9541  C CB  . TYR C 1 124 ? -70.201  -18.848 17.668  1.00 57.55  ? 184 TYR C CB  1 
ATOM   9542  C CG  . TYR C 1 124 ? -71.382  -19.686 18.118  1.00 57.06  ? 184 TYR C CG  1 
ATOM   9543  C CD1 . TYR C 1 124 ? -71.208  -20.867 18.827  1.00 60.04  ? 184 TYR C CD1 1 
ATOM   9544  C CD2 . TYR C 1 124 ? -72.675  -19.305 17.824  1.00 54.66  ? 184 TYR C CD2 1 
ATOM   9545  C CE1 . TYR C 1 124 ? -72.273  -21.659 19.208  1.00 63.84  ? 184 TYR C CE1 1 
ATOM   9546  C CE2 . TYR C 1 124 ? -73.758  -20.080 18.204  1.00 57.22  ? 184 TYR C CE2 1 
ATOM   9547  C CZ  . TYR C 1 124 ? -73.555  -21.250 18.917  1.00 61.39  ? 184 TYR C CZ  1 
ATOM   9548  O OH  . TYR C 1 124 ? -74.605  -22.018 19.323  1.00 74.37  ? 184 TYR C OH  1 
ATOM   9549  N N   . THR C 1 125 ? -70.178  -20.874 15.548  1.00 50.15  ? 185 THR C N   1 
ATOM   9550  C CA  . THR C 1 125 ? -70.405  -21.487 14.205  1.00 56.10  ? 185 THR C CA  1 
ATOM   9551  C C   . THR C 1 125 ? -70.222  -20.422 13.127  1.00 49.06  ? 185 THR C C   1 
ATOM   9552  O O   . THR C 1 125 ? -70.760  -19.318 13.256  1.00 45.39  ? 185 THR C O   1 
ATOM   9553  C CB  . THR C 1 125 ? -71.760  -22.203 14.115  1.00 65.49  ? 185 THR C CB  1 
ATOM   9554  O OG1 . THR C 1 125 ? -71.855  -22.916 12.878  1.00 63.22  ? 185 THR C OG1 1 
ATOM   9555  C CG2 . THR C 1 125 ? -72.934  -21.255 14.252  1.00 74.28  ? 185 THR C CG2 1 
ATOM   9556  N N   . PRO C 1 126 ? -69.464  -20.716 12.033  1.00 45.44  ? 186 PRO C N   1 
ATOM   9557  C CA  . PRO C 1 126 ? -68.911  -22.059 11.749  1.00 48.18  ? 186 PRO C CA  1 
ATOM   9558  C C   . PRO C 1 126 ? -67.447  -22.401 12.127  1.00 52.62  ? 186 PRO C C   1 
ATOM   9559  O O   . PRO C 1 126 ? -67.056  -23.603 12.104  1.00 54.12  ? 186 PRO C O   1 
ATOM   9560  C CB  . PRO C 1 126 ? -68.987  -22.042 10.225  1.00 45.95  ? 186 PRO C CB  1 
ATOM   9561  C CG  . PRO C 1 126 ? -68.561  -20.628 9.891   1.00 44.14  ? 186 PRO C CG  1 
ATOM   9562  C CD  . PRO C 1 126 ? -69.153  -19.747 10.972  1.00 40.98  ? 186 PRO C CD  1 
ATOM   9563  N N   . THR C 1 127 ? -66.646  -21.386 12.456  1.00 54.68  ? 187 THR C N   1 
ATOM   9564  C CA  . THR C 1 127 ? -65.192  -21.516 12.757  1.00 56.48  ? 187 THR C CA  1 
ATOM   9565  C C   . THR C 1 127 ? -64.975  -22.545 13.872  1.00 51.51  ? 187 THR C C   1 
ATOM   9566  O O   . THR C 1 127 ? -64.033  -23.334 13.784  1.00 46.42  ? 187 THR C O   1 
ATOM   9567  C CB  . THR C 1 127 ? -64.616  -20.154 13.164  1.00 47.88  ? 187 THR C CB  1 
ATOM   9568  O OG1 . THR C 1 127 ? -64.833  -19.246 12.088  1.00 41.45  ? 187 THR C OG1 1 
ATOM   9569  C CG2 . THR C 1 127 ? -63.145  -20.241 13.459  1.00 43.18  ? 187 THR C CG2 1 
ATOM   9570  N N   . VAL C 1 128 ? -65.823  -22.487 14.890  1.00 52.15  ? 188 VAL C N   1 
ATOM   9571  C CA  . VAL C 1 128 ? -65.711  -23.263 16.156  1.00 60.62  ? 188 VAL C CA  1 
ATOM   9572  C C   . VAL C 1 128 ? -65.750  -24.760 15.815  1.00 64.13  ? 188 VAL C C   1 
ATOM   9573  O O   . VAL C 1 128 ? -65.366  -25.601 16.672  1.00 64.30  ? 188 VAL C O   1 
ATOM   9574  C CB  . VAL C 1 128 ? -66.830  -22.856 17.134  1.00 57.09  ? 188 VAL C CB  1 
ATOM   9575  C CG1 . VAL C 1 128 ? -68.179  -23.355 16.649  1.00 57.90  ? 188 VAL C CG1 1 
ATOM   9576  C CG2 . VAL C 1 128 ? -66.543  -23.315 18.567  1.00 61.99  ? 188 VAL C CG2 1 
ATOM   9577  N N   . GLY C 1 129 ? -66.237  -25.084 14.623  1.00 59.35  ? 189 GLY C N   1 
ATOM   9578  C CA  . GLY C 1 129 ? -66.297  -26.466 14.141  1.00 64.74  ? 189 GLY C CA  1 
ATOM   9579  C C   . GLY C 1 129 ? -64.915  -26.934 13.758  1.00 67.33  ? 189 GLY C C   1 
ATOM   9580  O O   . GLY C 1 129 ? -64.509  -27.990 14.236  1.00 74.02  ? 189 GLY C O   1 
ATOM   9581  N N   . GLU C 1 130 ? -64.241  -26.170 12.897  1.00 71.25  ? 190 GLU C N   1 
ATOM   9582  C CA  . GLU C 1 130 ? -62.842  -26.411 12.455  1.00 60.53  ? 190 GLU C CA  1 
ATOM   9583  C C   . GLU C 1 130 ? -61.954  -26.465 13.708  1.00 63.88  ? 190 GLU C C   1 
ATOM   9584  O O   . GLU C 1 130 ? -61.152  -27.421 13.839  1.00 69.27  ? 190 GLU C O   1 
ATOM   9585  C CB  . GLU C 1 130 ? -62.425  -25.308 11.480  1.00 58.47  ? 190 GLU C CB  1 
ATOM   9586  C CG  . GLU C 1 130 ? -60.961  -25.376 11.109  1.00 69.33  ? 190 GLU C CG  1 
ATOM   9587  C CD  . GLU C 1 130 ? -60.478  -24.495 9.972   1.00 68.41  ? 190 GLU C CD  1 
ATOM   9588  O OE1 . GLU C 1 130 ? -60.733  -23.272 10.005  1.00 100.44 ? 190 GLU C OE1 1 
ATOM   9589  O OE2 . GLU C 1 130 ? -59.806  -25.022 9.090   1.00 62.23  ? 190 GLU C OE2 1 
ATOM   9590  N N   . ALA C 1 131 ? -62.112  -25.493 14.620  1.00 55.39  ? 191 ALA C N   1 
ATOM   9591  C CA  . ALA C 1 131 ? -61.342  -25.435 15.879  1.00 51.17  ? 191 ALA C CA  1 
ATOM   9592  C C   . ALA C 1 131 ? -61.447  -26.804 16.565  1.00 45.91  ? 191 ALA C C   1 
ATOM   9593  O O   . ALA C 1 131 ? -60.432  -27.293 17.024  1.00 50.86  ? 191 ALA C O   1 
ATOM   9594  C CB  . ALA C 1 131 ? -61.799  -24.311 16.773  1.00 44.98  ? 191 ALA C CB  1 
ATOM   9595  N N   . CYS C 1 132 ? -62.617  -27.431 16.596  1.00 46.15  ? 192 CYS C N   1 
ATOM   9596  C CA  . CYS C 1 132 ? -62.806  -28.735 17.295  1.00 51.63  ? 192 CYS C CA  1 
ATOM   9597  C C   . CYS C 1 132 ? -62.144  -29.866 16.508  1.00 50.13  ? 192 CYS C C   1 
ATOM   9598  O O   . CYS C 1 132 ? -61.692  -30.832 17.135  1.00 51.59  ? 192 CYS C O   1 
ATOM   9599  C CB  . CYS C 1 132 ? -64.272  -29.077 17.520  1.00 55.33  ? 192 CYS C CB  1 
ATOM   9600  S SG  . CYS C 1 132 ? -65.018  -28.129 18.864  1.00 62.18  ? 192 CYS C SG  1 
ATOM   9601  N N   . GLN C 1 133 ? -62.097  -29.760 15.184  1.00 51.39  ? 193 GLN C N   1 
ATOM   9602  C CA  . GLN C 1 133 ? -61.535  -30.830 14.328  1.00 58.73  ? 193 GLN C CA  1 
ATOM   9603  C C   . GLN C 1 133 ? -60.020  -30.853 14.490  1.00 58.66  ? 193 GLN C C   1 
ATOM   9604  O O   . GLN C 1 133 ? -59.428  -31.956 14.404  1.00 66.03  ? 193 GLN C O   1 
ATOM   9605  C CB  . GLN C 1 133 ? -61.934  -30.608 12.876  1.00 56.93  ? 193 GLN C CB  1 
ATOM   9606  C CG  . GLN C 1 133 ? -63.362  -31.023 12.602  1.00 59.65  ? 193 GLN C CG  1 
ATOM   9607  C CD  . GLN C 1 133 ? -63.775  -30.671 11.203  1.00 55.52  ? 193 GLN C CD  1 
ATOM   9608  O OE1 . GLN C 1 133 ? -63.636  -29.527 10.769  1.00 53.92  ? 193 GLN C OE1 1 
ATOM   9609  N NE2 . GLN C 1 133 ? -64.346  -31.656 10.540  1.00 53.47  ? 193 GLN C NE2 1 
ATOM   9610  N N   . LYS C 1 134 ? -59.441  -29.674 14.716  1.00 63.55  ? 194 LYS C N   1 
ATOM   9611  C CA  . LYS C 1 134 ? -57.974  -29.440 14.798  1.00 64.09  ? 194 LYS C CA  1 
ATOM   9612  C C   . LYS C 1 134 ? -57.573  -29.000 16.215  1.00 58.70  ? 194 LYS C C   1 
ATOM   9613  O O   . LYS C 1 134 ? -56.534  -28.390 16.311  1.00 60.15  ? 194 LYS C O   1 
ATOM   9614  C CB  . LYS C 1 134 ? -57.555  -28.370 13.779  1.00 60.58  ? 194 LYS C CB  1 
ATOM   9615  C CG  . LYS C 1 134 ? -57.768  -28.777 12.325  1.00 64.39  ? 194 LYS C CG  1 
ATOM   9616  C CD  . LYS C 1 134 ? -57.817  -27.652 11.326  1.00 65.13  ? 194 LYS C CD  1 
ATOM   9617  C CE  . LYS C 1 134 ? -57.754  -28.181 9.908   1.00 76.28  ? 194 LYS C CE  1 
ATOM   9618  N NZ  . LYS C 1 134 ? -57.398  -27.108 8.955   1.00 91.60  ? 194 LYS C NZ  1 
ATOM   9619  N N   . TYR C 1 135 ? -58.339  -29.337 17.257  1.00 54.77  ? 195 TYR C N   1 
ATOM   9620  C CA  . TYR C 1 135 ? -58.145  -28.803 18.627  1.00 56.36  ? 195 TYR C CA  1 
ATOM   9621  C C   . TYR C 1 135 ? -56.757  -29.190 19.135  1.00 59.13  ? 195 TYR C C   1 
ATOM   9622  O O   . TYR C 1 135 ? -56.032  -28.295 19.671  1.00 54.53  ? 195 TYR C O   1 
ATOM   9623  C CB  . TYR C 1 135 ? -59.211  -29.314 19.593  1.00 63.03  ? 195 TYR C CB  1 
ATOM   9624  C CG  . TYR C 1 135 ? -59.588  -28.337 20.687  1.00 70.42  ? 195 TYR C CG  1 
ATOM   9625  C CD1 . TYR C 1 135 ? -60.183  -27.110 20.381  1.00 71.11  ? 195 TYR C CD1 1 
ATOM   9626  C CD2 . TYR C 1 135 ? -59.414  -28.656 22.024  1.00 66.10  ? 195 TYR C CD2 1 
ATOM   9627  C CE1 . TYR C 1 135 ? -60.568  -26.211 21.359  1.00 57.81  ? 195 TYR C CE1 1 
ATOM   9628  C CE2 . TYR C 1 135 ? -59.791  -27.768 23.019  1.00 70.96  ? 195 TYR C CE2 1 
ATOM   9629  C CZ  . TYR C 1 135 ? -60.378  -26.552 22.685  1.00 67.94  ? 195 TYR C CZ  1 
ATOM   9630  O OH  . TYR C 1 135 ? -60.768  -25.692 23.669  1.00 61.59  ? 195 TYR C OH  1 
ATOM   9631  N N   . GLY C 1 136 ? -56.399  -30.467 18.935  1.00 53.77  ? 196 GLY C N   1 
ATOM   9632  C CA  . GLY C 1 136 ? -55.139  -31.053 19.432  1.00 48.93  ? 196 GLY C CA  1 
ATOM   9633  C C   . GLY C 1 136 ? -53.912  -30.346 18.855  1.00 45.76  ? 196 GLY C C   1 
ATOM   9634  O O   . GLY C 1 136 ? -52.921  -30.235 19.550  1.00 44.18  ? 196 GLY C O   1 
ATOM   9635  N N   . SER C 1 137 ? -53.969  -29.903 17.604  1.00 47.96  ? 197 SER C N   1 
ATOM   9636  C CA  . SER C 1 137 ? -52.818  -29.380 16.826  1.00 52.94  ? 197 SER C CA  1 
ATOM   9637  C C   . SER C 1 137 ? -52.744  -27.849 16.945  1.00 55.46  ? 197 SER C C   1 
ATOM   9638  O O   . SER C 1 137 ? -51.788  -27.244 16.407  1.00 53.57  ? 197 SER C O   1 
ATOM   9639  C CB  . SER C 1 137 ? -52.906  -29.821 15.391  1.00 49.04  ? 197 SER C CB  1 
ATOM   9640  O OG  . SER C 1 137 ? -53.927  -29.106 14.723  1.00 45.73  ? 197 SER C OG  1 
ATOM   9641  N N   . ILE C 1 138 ? -53.718  -27.231 17.621  1.00 60.76  ? 198 ILE C N   1 
ATOM   9642  C CA  . ILE C 1 138 ? -53.813  -25.747 17.760  1.00 85.41  ? 198 ILE C CA  1 
ATOM   9643  C C   . ILE C 1 138 ? -53.067  -25.381 19.038  1.00 102.95 ? 198 ILE C C   1 
ATOM   9644  O O   . ILE C 1 138 ? -53.142  -26.162 20.005  1.00 89.75  ? 198 ILE C O   1 
ATOM   9645  C CB  . ILE C 1 138 ? -55.277  -25.240 17.747  1.00 87.24  ? 198 ILE C CB  1 
ATOM   9646  C CG1 . ILE C 1 138 ? -55.899  -25.276 16.352  1.00 85.14  ? 198 ILE C CG1 1 
ATOM   9647  C CG2 . ILE C 1 138 ? -55.365  -23.830 18.272  1.00 94.29  ? 198 ILE C CG2 1 
ATOM   9648  C CD1 . ILE C 1 138 ? -54.978  -24.754 15.294  1.00 87.96  ? 198 ILE C CD1 1 
ATOM   9649  N N   . PHE C 1 139 ? -52.351  -24.250 19.017  1.00 119.13 ? 199 PHE C N   1 
ATOM   9650  C CA  . PHE C 1 139 ? -51.667  -23.660 20.200  1.00 118.87 ? 199 PHE C CA  1 
ATOM   9651  C C   . PHE C 1 139 ? -52.737  -23.353 21.253  1.00 109.09 ? 199 PHE C C   1 
ATOM   9652  O O   . PHE C 1 139 ? -53.653  -22.571 20.965  1.00 95.02  ? 199 PHE C O   1 
ATOM   9653  C CB  . PHE C 1 139 ? -50.827  -22.445 19.804  1.00 128.72 ? 199 PHE C CB  1 
ATOM   9654  C CG  . PHE C 1 139 ? -50.335  -21.609 20.957  1.00 127.35 ? 199 PHE C CG  1 
ATOM   9655  C CD1 . PHE C 1 139 ? -51.018  -20.455 21.306  1.00 124.50 ? 199 PHE C CD1 1 
ATOM   9656  C CD2 . PHE C 1 139 ? -49.183  -21.942 21.661  1.00 110.50 ? 199 PHE C CD2 1 
ATOM   9657  C CE1 . PHE C 1 139 ? -50.575  -19.659 22.351  1.00 122.10 ? 199 PHE C CE1 1 
ATOM   9658  C CE2 . PHE C 1 139 ? -48.746  -21.148 22.708  1.00 109.12 ? 199 PHE C CE2 1 
ATOM   9659  C CZ  . PHE C 1 139 ? -49.440  -20.009 23.049  1.00 111.91 ? 199 PHE C CZ  1 
ATOM   9660  N N   . ARG C 1 140 ? -52.609  -23.965 22.426  1.00 118.92 ? 200 ARG C N   1 
ATOM   9661  C CA  . ARG C 1 140 ? -53.738  -24.181 23.380  1.00 124.14 ? 200 ARG C CA  1 
ATOM   9662  C C   . ARG C 1 140 ? -53.369  -23.547 24.722  1.00 103.65 ? 200 ARG C C   1 
ATOM   9663  O O   . ARG C 1 140 ? -52.501  -24.129 25.416  1.00 84.78  ? 200 ARG C O   1 
ATOM   9664  C CB  . ARG C 1 140 ? -54.125  -25.672 23.531  1.00 141.00 ? 200 ARG C CB  1 
ATOM   9665  C CG  . ARG C 1 140 ? -53.080  -26.708 23.110  1.00 131.26 ? 200 ARG C CG  1 
ATOM   9666  C CD  . ARG C 1 140 ? -51.976  -26.948 24.135  1.00 125.15 ? 200 ARG C CD  1 
ATOM   9667  N NE  . ARG C 1 140 ? -50.821  -27.713 23.637  1.00 116.69 ? 200 ARG C NE  1 
ATOM   9668  C CZ  . ARG C 1 140 ? -49.673  -27.925 24.294  1.00 74.04  ? 200 ARG C CZ  1 
ATOM   9669  N NH1 . ARG C 1 140 ? -49.473  -27.458 25.511  1.00 80.75  ? 200 ARG C NH1 1 
ATOM   9670  N NH2 . ARG C 1 140 ? -48.720  -28.632 23.742  1.00 56.52  ? 200 ARG C NH2 1 
ATOM   9671  N N   . ARG C 1 141 ? -53.974  -22.400 25.046  1.00 94.94  ? 201 ARG C N   1 
ATOM   9672  C CA  . ARG C 1 141 ? -54.060  -21.903 26.439  1.00 106.83 ? 201 ARG C CA  1 
ATOM   9673  C C   . ARG C 1 141 ? -55.166  -22.719 27.115  1.00 105.89 ? 201 ARG C C   1 
ATOM   9674  O O   . ARG C 1 141 ? -56.247  -22.826 26.544  1.00 134.57 ? 201 ARG C O   1 
ATOM   9675  C CB  . ARG C 1 141 ? -54.274  -20.378 26.437  1.00 111.60 ? 201 ARG C CB  1 
ATOM   9676  C CG  . ARG C 1 141 ? -53.057  -19.590 26.903  1.00 109.19 ? 201 ARG C CG  1 
ATOM   9677  C CD  . ARG C 1 141 ? -52.028  -19.319 25.833  1.00 120.62 ? 201 ARG C CD  1 
ATOM   9678  N NE  . ARG C 1 141 ? -51.099  -18.305 26.318  1.00 135.80 ? 201 ARG C NE  1 
ATOM   9679  C CZ  . ARG C 1 141 ? -51.325  -16.983 26.343  1.00 126.90 ? 201 ARG C CZ  1 
ATOM   9680  N NH1 . ARG C 1 141 ? -52.475  -16.496 25.913  1.00 108.98 ? 201 ARG C NH1 1 
ATOM   9681  N NH2 . ARG C 1 141 ? -50.405  -16.143 26.801  1.00 125.04 ? 201 ARG C NH2 1 
ATOM   9682  N N   . PRO C 1 142 ? -54.934  -23.362 28.290  1.00 94.90  ? 202 PRO C N   1 
ATOM   9683  C CA  . PRO C 1 142 ? -55.960  -24.192 28.928  1.00 90.48  ? 202 PRO C CA  1 
ATOM   9684  C C   . PRO C 1 142 ? -57.263  -23.456 29.334  1.00 85.04  ? 202 PRO C C   1 
ATOM   9685  O O   . PRO C 1 142 ? -57.267  -22.341 29.835  1.00 58.93  ? 202 PRO C O   1 
ATOM   9686  C CB  . PRO C 1 142 ? -55.251  -24.835 30.136  1.00 97.33  ? 202 PRO C CB  1 
ATOM   9687  C CG  . PRO C 1 142 ? -54.034  -23.974 30.386  1.00 99.53  ? 202 PRO C CG  1 
ATOM   9688  C CD  . PRO C 1 142 ? -53.683  -23.346 29.057  1.00 96.53  ? 202 PRO C CD  1 
ATOM   9689  N N   . GLN C 1 143 ? -58.384  -24.121 29.038  1.00 88.54  ? 203 GLN C N   1 
ATOM   9690  C CA  . GLN C 1 143 ? -59.785  -23.642 29.170  1.00 62.42  ? 203 GLN C CA  1 
ATOM   9691  C C   . GLN C 1 143 ? -60.650  -24.874 29.468  1.00 52.44  ? 203 GLN C C   1 
ATOM   9692  O O   . GLN C 1 143 ? -60.442  -25.983 28.834  1.00 47.25  ? 203 GLN C O   1 
ATOM   9693  C CB  . GLN C 1 143 ? -60.242  -22.990 27.873  1.00 58.15  ? 203 GLN C CB  1 
ATOM   9694  C CG  . GLN C 1 143 ? -59.721  -21.594 27.683  1.00 59.87  ? 203 GLN C CG  1 
ATOM   9695  C CD  . GLN C 1 143 ? -60.059  -21.015 26.326  1.00 61.01  ? 203 GLN C CD  1 
ATOM   9696  O OE1 . GLN C 1 143 ? -59.995  -21.692 25.309  1.00 56.22  ? 203 GLN C OE1 1 
ATOM   9697  N NE2 . GLN C 1 143 ? -60.408  -19.737 26.294  1.00 54.80  ? 203 GLN C NE2 1 
ATOM   9698  N N   . GLY C 1 144 ? -61.519  -24.724 30.450  1.00 47.75  ? 204 GLY C N   1 
ATOM   9699  C CA  . GLY C 1 144 ? -62.462  -25.787 30.838  1.00 55.26  ? 204 GLY C CA  1 
ATOM   9700  C C   . GLY C 1 144 ? -61.838  -26.952 31.586  1.00 47.05  ? 204 GLY C C   1 
ATOM   9701  O O   . GLY C 1 144 ? -60.628  -26.998 31.754  1.00 53.26  ? 204 GLY C O   1 
ATOM   9702  N N   . LEU C 1 145 ? -62.683  -27.872 32.006  1.00 42.64  ? 205 LEU C N   1 
ATOM   9703  C CA  . LEU C 1 145 ? -62.318  -29.025 32.857  1.00 51.09  ? 205 LEU C CA  1 
ATOM   9704  C C   . LEU C 1 145 ? -62.581  -30.322 32.088  1.00 44.14  ? 205 LEU C C   1 
ATOM   9705  O O   . LEU C 1 145 ? -63.674  -30.454 31.536  1.00 42.86  ? 205 LEU C O   1 
ATOM   9706  C CB  . LEU C 1 145 ? -63.193  -28.976 34.105  1.00 59.15  ? 205 LEU C CB  1 
ATOM   9707  C CG  . LEU C 1 145 ? -62.508  -28.790 35.446  1.00 59.97  ? 205 LEU C CG  1 
ATOM   9708  C CD1 . LEU C 1 145 ? -63.571  -28.716 36.502  1.00 57.34  ? 205 LEU C CD1 1 
ATOM   9709  C CD2 . LEU C 1 145 ? -61.563  -29.936 35.730  1.00 65.67  ? 205 LEU C CD2 1 
ATOM   9710  N N   . TYR C 1 146 ? -61.625  -31.249 32.068  1.00 41.33  ? 206 TYR C N   1 
ATOM   9711  C CA  . TYR C 1 146 ? -61.780  -32.556 31.382  1.00 45.36  ? 206 TYR C CA  1 
ATOM   9712  C C   . TYR C 1 146 ? -61.911  -33.641 32.443  1.00 43.15  ? 206 TYR C C   1 
ATOM   9713  O O   . TYR C 1 146 ? -60.979  -33.833 33.247  1.00 42.22  ? 206 TYR C O   1 
ATOM   9714  C CB  . TYR C 1 146 ? -60.614  -32.850 30.435  1.00 45.97  ? 206 TYR C CB  1 
ATOM   9715  C CG  . TYR C 1 146 ? -60.310  -31.780 29.412  1.00 51.62  ? 206 TYR C CG  1 
ATOM   9716  C CD1 . TYR C 1 146 ? -59.779  -30.554 29.796  1.00 56.62  ? 206 TYR C CD1 1 
ATOM   9717  C CD2 . TYR C 1 146 ? -60.533  -31.993 28.061  1.00 50.60  ? 206 TYR C CD2 1 
ATOM   9718  C CE1 . TYR C 1 146 ? -59.476  -29.566 28.874  1.00 55.06  ? 206 TYR C CE1 1 
ATOM   9719  C CE2 . TYR C 1 146 ? -60.237  -31.014 27.126  1.00 52.32  ? 206 TYR C CE2 1 
ATOM   9720  C CZ  . TYR C 1 146 ? -59.704  -29.797 27.534  1.00 51.58  ? 206 TYR C CZ  1 
ATOM   9721  O OH  . TYR C 1 146 ? -59.398  -28.780 26.674  1.00 47.97  ? 206 TYR C OH  1 
ATOM   9722  N N   . VAL C 1 147 ? -63.045  -34.332 32.442  1.00 43.88  ? 207 VAL C N   1 
ATOM   9723  C CA  . VAL C 1 147 ? -63.290  -35.521 33.318  1.00 44.75  ? 207 VAL C CA  1 
ATOM   9724  C C   . VAL C 1 147 ? -63.205  -36.783 32.477  1.00 40.60  ? 207 VAL C C   1 
ATOM   9725  O O   . VAL C 1 147 ? -64.090  -37.005 31.640  1.00 52.40  ? 207 VAL C O   1 
ATOM   9726  C CB  . VAL C 1 147 ? -64.663  -35.434 33.983  1.00 50.31  ? 207 VAL C CB  1 
ATOM   9727  C CG1 . VAL C 1 147 ? -64.913  -36.664 34.834  1.00 48.56  ? 207 VAL C CG1 1 
ATOM   9728  C CG2 . VAL C 1 147 ? -64.822  -34.108 34.740  1.00 58.31  ? 207 VAL C CG2 1 
ATOM   9729  N N   . SER C 1 148 ? -62.160  -37.571 32.642  1.00 45.19  ? 208 SER C N   1 
ATOM   9730  C CA  . SER C 1 148 ? -61.944  -38.781 31.803  1.00 46.81  ? 208 SER C CA  1 
ATOM   9731  C C   . SER C 1 148 ? -62.535  -39.982 32.509  1.00 43.73  ? 208 SER C C   1 
ATOM   9732  O O   . SER C 1 148 ? -62.980  -39.845 33.642  1.00 42.48  ? 208 SER C O   1 
ATOM   9733  C CB  . SER C 1 148 ? -60.496  -39.013 31.461  1.00 48.55  ? 208 SER C CB  1 
ATOM   9734  O OG  . SER C 1 148 ? -59.775  -39.423 32.603  1.00 55.72  ? 208 SER C OG  1 
ATOM   9735  N N   . LEU C 1 149 ? -62.526  -41.105 31.818  1.00 53.61  ? 209 LEU C N   1 
ATOM   9736  C CA  . LEU C 1 149 ? -62.847  -42.450 32.367  1.00 58.63  ? 209 LEU C CA  1 
ATOM   9737  C C   . LEU C 1 149 ? -61.852  -42.825 33.452  1.00 56.95  ? 209 LEU C C   1 
ATOM   9738  O O   . LEU C 1 149 ? -62.196  -43.659 34.276  1.00 66.61  ? 209 LEU C O   1 
ATOM   9739  C CB  . LEU C 1 149 ? -62.784  -43.491 31.254  1.00 60.62  ? 209 LEU C CB  1 
ATOM   9740  C CG  . LEU C 1 149 ? -64.134  -43.898 30.698  1.00 62.77  ? 209 LEU C CG  1 
ATOM   9741  C CD1 . LEU C 1 149 ? -63.943  -44.667 29.413  1.00 75.80  ? 209 LEU C CD1 1 
ATOM   9742  C CD2 . LEU C 1 149 ? -64.909  -44.701 31.723  1.00 64.49  ? 209 LEU C CD2 1 
ATOM   9743  N N   . LYS C 1 150 ? -60.668  -42.235 33.437  1.00 60.64  ? 210 LYS C N   1 
ATOM   9744  C CA  . LYS C 1 150 ? -59.592  -42.552 34.407  1.00 67.30  ? 210 LYS C CA  1 
ATOM   9745  C C   . LYS C 1 150 ? -59.753  -41.658 35.652  1.00 65.89  ? 210 LYS C C   1 
ATOM   9746  O O   . LYS C 1 150 ? -58.852  -41.707 36.505  1.00 61.88  ? 210 LYS C O   1 
ATOM   9747  C CB  . LYS C 1 150 ? -58.199  -42.338 33.778  1.00 78.71  ? 210 LYS C CB  1 
ATOM   9748  C CG  . LYS C 1 150 ? -57.931  -42.903 32.384  1.00 91.75  ? 210 LYS C CG  1 
ATOM   9749  C CD  . LYS C 1 150 ? -57.464  -44.364 32.368  1.00 102.91 ? 210 LYS C CD  1 
ATOM   9750  C CE  . LYS C 1 150 ? -58.567  -45.365 32.063  1.00 99.78  ? 210 LYS C CE  1 
ATOM   9751  N NZ  . LYS C 1 150 ? -58.464  -46.573 32.917  1.00 96.58  ? 210 LYS C NZ  1 
ATOM   9752  N N   . ASP C 1 151 ? -60.841  -40.871 35.754  1.00 63.01  ? 211 ASP C N   1 
ATOM   9753  C CA  . ASP C 1 151 ? -61.131  -39.993 36.915  1.00 59.71  ? 211 ASP C CA  1 
ATOM   9754  C C   . ASP C 1 151 ? -62.299  -40.619 37.696  1.00 63.11  ? 211 ASP C C   1 
ATOM   9755  O O   . ASP C 1 151 ? -62.832  -39.963 38.631  1.00 63.68  ? 211 ASP C O   1 
ATOM   9756  C CB  . ASP C 1 151 ? -61.343  -38.541 36.465  1.00 59.28  ? 211 ASP C CB  1 
ATOM   9757  C CG  . ASP C 1 151 ? -60.175  -37.941 35.695  1.00 69.84  ? 211 ASP C CG  1 
ATOM   9758  O OD1 . ASP C 1 151 ? -59.030  -38.172 36.108  1.00 81.68  ? 211 ASP C OD1 1 
ATOM   9759  O OD2 . ASP C 1 151 ? -60.404  -37.248 34.674  1.00 77.42  ? 211 ASP C OD2 1 
ATOM   9760  N N   . LYS C 1 152 ? -62.677  -41.862 37.376  1.00 66.50  ? 212 LYS C N   1 
ATOM   9761  C CA  . LYS C 1 152 ? -63.877  -42.493 37.999  1.00 75.36  ? 212 LYS C CA  1 
ATOM   9762  C C   . LYS C 1 152 ? -63.460  -42.976 39.377  1.00 71.67  ? 212 LYS C C   1 
ATOM   9763  O O   . LYS C 1 152 ? -62.322  -43.409 39.527  1.00 84.49  ? 212 LYS C O   1 
ATOM   9764  C CB  . LYS C 1 152 ? -64.526  -43.573 37.135  1.00 79.30  ? 212 LYS C CB  1 
ATOM   9765  C CG  . LYS C 1 152 ? -64.246  -45.028 37.497  1.00 82.10  ? 212 LYS C CG  1 
ATOM   9766  C CD  . LYS C 1 152 ? -65.348  -45.964 37.039  1.00 88.86  ? 212 LYS C CD  1 
ATOM   9767  C CE  . LYS C 1 152 ? -65.375  -46.163 35.529  1.00 94.20  ? 212 LYS C CE  1 
ATOM   9768  N NZ  . LYS C 1 152 ? -64.073  -46.645 34.975  1.00 84.46  ? 212 LYS C NZ  1 
ATOM   9769  N N   . GLY C 1 153 ? -64.354  -42.842 40.348  1.00 73.04  ? 213 GLY C N   1 
ATOM   9770  C CA  . GLY C 1 153 ? -63.999  -42.888 41.776  1.00 71.93  ? 213 GLY C CA  1 
ATOM   9771  C C   . GLY C 1 153 ? -63.596  -41.517 42.292  1.00 63.56  ? 213 GLY C C   1 
ATOM   9772  O O   . GLY C 1 153 ? -63.793  -41.293 43.490  1.00 59.14  ? 213 GLY C O   1 
ATOM   9773  N N   . LYS C 1 154 ? -63.054  -40.634 41.446  1.00 62.00  ? 214 LYS C N   1 
ATOM   9774  C CA  . LYS C 1 154 ? -62.383  -39.386 41.911  1.00 65.45  ? 214 LYS C CA  1 
ATOM   9775  C C   . LYS C 1 154 ? -62.902  -38.169 41.148  1.00 62.11  ? 214 LYS C C   1 
ATOM   9776  O O   . LYS C 1 154 ? -62.184  -37.165 41.094  1.00 55.77  ? 214 LYS C O   1 
ATOM   9777  C CB  . LYS C 1 154 ? -60.860  -39.495 41.739  1.00 69.95  ? 214 LYS C CB  1 
ATOM   9778  C CG  . LYS C 1 154 ? -60.237  -40.826 42.154  1.00 83.39  ? 214 LYS C CG  1 
ATOM   9779  C CD  . LYS C 1 154 ? -58.802  -40.740 42.665  1.00 91.07  ? 214 LYS C CD  1 
ATOM   9780  C CE  . LYS C 1 154 ? -58.473  -41.822 43.678  1.00 93.36  ? 214 LYS C CE  1 
ATOM   9781  N NZ  . LYS C 1 154 ? -57.016  -41.890 43.951  1.00 94.33  ? 214 LYS C NZ  1 
ATOM   9782  N N   . VAL C 1 155 ? -64.093  -38.237 40.562  1.00 57.75  ? 215 VAL C N   1 
ATOM   9783  C CA  . VAL C 1 155 ? -64.630  -37.119 39.738  1.00 51.95  ? 215 VAL C CA  1 
ATOM   9784  C C   . VAL C 1 155 ? -64.751  -35.865 40.612  1.00 58.47  ? 215 VAL C C   1 
ATOM   9785  O O   . VAL C 1 155 ? -64.498  -34.766 40.133  1.00 55.08  ? 215 VAL C O   1 
ATOM   9786  C CB  . VAL C 1 155 ? -65.986  -37.486 39.134  1.00 52.84  ? 215 VAL C CB  1 
ATOM   9787  C CG1 . VAL C 1 155 ? -66.629  -36.268 38.488  1.00 60.11  ? 215 VAL C CG1 1 
ATOM   9788  C CG2 . VAL C 1 155 ? -65.870  -38.642 38.157  1.00 52.98  ? 215 VAL C CG2 1 
ATOM   9789  N N   . LEU C 1 156 ? -65.175  -36.030 41.858  1.00 68.72  ? 216 LEU C N   1 
ATOM   9790  C CA  . LEU C 1 156 ? -65.358  -34.886 42.778  1.00 71.02  ? 216 LEU C CA  1 
ATOM   9791  C C   . LEU C 1 156 ? -63.997  -34.248 43.047  1.00 74.65  ? 216 LEU C C   1 
ATOM   9792  O O   . LEU C 1 156 ? -63.964  -33.000 43.112  1.00 83.65  ? 216 LEU C O   1 
ATOM   9793  C CB  . LEU C 1 156 ? -66.012  -35.395 44.058  1.00 67.29  ? 216 LEU C CB  1 
ATOM   9794  C CG  . LEU C 1 156 ? -66.327  -34.355 45.131  1.00 67.05  ? 216 LEU C CG  1 
ATOM   9795  C CD1 . LEU C 1 156 ? -66.920  -33.054 44.575  1.00 64.03  ? 216 LEU C CD1 1 
ATOM   9796  C CD2 . LEU C 1 156 ? -67.260  -34.989 46.143  1.00 69.76  ? 216 LEU C CD2 1 
ATOM   9797  N N   . GLU C 1 157 ? -62.953  -35.076 43.214  1.00 80.20  ? 217 GLU C N   1 
ATOM   9798  C CA  . GLU C 1 157 ? -61.533  -34.637 43.371  1.00 84.04  ? 217 GLU C CA  1 
ATOM   9799  C C   . GLU C 1 157 ? -61.177  -33.669 42.228  1.00 71.01  ? 217 GLU C C   1 
ATOM   9800  O O   . GLU C 1 157 ? -60.527  -32.622 42.491  1.00 64.58  ? 217 GLU C O   1 
ATOM   9801  C CB  . GLU C 1 157 ? -60.528  -35.798 43.315  1.00 91.77  ? 217 GLU C CB  1 
ATOM   9802  C CG  . GLU C 1 157 ? -60.327  -36.573 44.596  1.00 109.61 ? 217 GLU C CG  1 
ATOM   9803  C CD  . GLU C 1 157 ? -59.026  -37.376 44.652  1.00 119.53 ? 217 GLU C CD  1 
ATOM   9804  O OE1 . GLU C 1 157 ? -57.991  -36.970 44.030  1.00 93.03  ? 217 GLU C OE1 1 
ATOM   9805  O OE2 . GLU C 1 157 ? -59.066  -38.463 45.265  1.00 125.83 ? 217 GLU C OE2 1 
ATOM   9806  N N   . VAL C 1 158 ? -61.596  -34.009 41.007  1.00 56.70  ? 218 VAL C N   1 
ATOM   9807  C CA  . VAL C 1 158 ? -61.289  -33.234 39.774  1.00 60.09  ? 218 VAL C CA  1 
ATOM   9808  C C   . VAL C 1 158 ? -62.060  -31.907 39.851  1.00 59.95  ? 218 VAL C C   1 
ATOM   9809  O O   . VAL C 1 158 ? -61.470  -30.854 39.575  1.00 60.29  ? 218 VAL C O   1 
ATOM   9810  C CB  . VAL C 1 158 ? -61.623  -34.037 38.494  1.00 63.67  ? 218 VAL C CB  1 
ATOM   9811  C CG1 . VAL C 1 158 ? -61.367  -33.252 37.214  1.00 59.84  ? 218 VAL C CG1 1 
ATOM   9812  C CG2 . VAL C 1 158 ? -60.884  -35.377 38.442  1.00 74.39  ? 218 VAL C CG2 1 
ATOM   9813  N N   . LEU C 1 159 ? -63.331  -31.944 40.243  1.00 59.16  ? 219 LEU C N   1 
ATOM   9814  C CA  . LEU C 1 159 ? -64.163  -30.725 40.341  1.00 55.26  ? 219 LEU C CA  1 
ATOM   9815  C C   . LEU C 1 159 ? -63.445  -29.726 41.265  1.00 55.47  ? 219 LEU C C   1 
ATOM   9816  O O   . LEU C 1 159 ? -63.408  -28.491 40.976  1.00 49.49  ? 219 LEU C O   1 
ATOM   9817  C CB  . LEU C 1 159 ? -65.558  -31.140 40.834  1.00 56.74  ? 219 LEU C CB  1 
ATOM   9818  C CG  . LEU C 1 159 ? -66.570  -31.517 39.745  1.00 53.59  ? 219 LEU C CG  1 
ATOM   9819  C CD1 . LEU C 1 159 ? -67.806  -32.175 40.326  1.00 57.93  ? 219 LEU C CD1 1 
ATOM   9820  C CD2 . LEU C 1 159 ? -66.974  -30.285 38.969  1.00 50.86  ? 219 LEU C CD2 1 
ATOM   9821  N N   . ARG C 1 160 ? -62.853  -30.253 42.326  1.00 61.67  ? 220 ARG C N   1 
ATOM   9822  C CA  . ARG C 1 160 ? -62.339  -29.425 43.446  1.00 70.71  ? 220 ARG C CA  1 
ATOM   9823  C C   . ARG C 1 160 ? -61.213  -28.543 42.903  1.00 68.16  ? 220 ARG C C   1 
ATOM   9824  O O   . ARG C 1 160 ? -61.002  -27.466 43.469  1.00 84.50  ? 220 ARG C O   1 
ATOM   9825  C CB  . ARG C 1 160 ? -61.888  -30.313 44.616  1.00 76.97  ? 220 ARG C CB  1 
ATOM   9826  C CG  . ARG C 1 160 ? -63.049  -30.889 45.408  1.00 86.79  ? 220 ARG C CG  1 
ATOM   9827  C CD  . ARG C 1 160 ? -62.667  -31.575 46.698  1.00 87.77  ? 220 ARG C CD  1 
ATOM   9828  N NE  . ARG C 1 160 ? -63.886  -32.127 47.305  1.00 90.64  ? 220 ARG C NE  1 
ATOM   9829  C CZ  . ARG C 1 160 ? -64.706  -31.473 48.143  1.00 89.49  ? 220 ARG C CZ  1 
ATOM   9830  N NH1 . ARG C 1 160 ? -64.460  -30.228 48.544  1.00 89.60  ? 220 ARG C NH1 1 
ATOM   9831  N NH2 . ARG C 1 160 ? -65.773  -32.093 48.610  1.00 87.26  ? 220 ARG C NH2 1 
ATOM   9832  N N   . ASN C 1 161 ? -60.545  -28.991 41.838  1.00 61.95  ? 221 ASN C N   1 
ATOM   9833  C CA  . ASN C 1 161 ? -59.351  -28.328 41.263  1.00 55.28  ? 221 ASN C CA  1 
ATOM   9834  C C   . ASN C 1 161 ? -59.757  -27.033 40.565  1.00 49.81  ? 221 ASN C C   1 
ATOM   9835  O O   . ASN C 1 161 ? -58.898  -26.175 40.398  1.00 41.39  ? 221 ASN C O   1 
ATOM   9836  C CB  . ASN C 1 161 ? -58.603  -29.253 40.302  1.00 57.87  ? 221 ASN C CB  1 
ATOM   9837  C CG  . ASN C 1 161 ? -57.766  -30.305 40.998  1.00 60.57  ? 221 ASN C CG  1 
ATOM   9838  O OD1 . ASN C 1 161 ? -57.377  -30.123 42.149  1.00 66.37  ? 221 ASN C OD1 1 
ATOM   9839  N ND2 . ASN C 1 161 ? -57.442  -31.383 40.294  1.00 60.22  ? 221 ASN C ND2 1 
ATOM   9840  N N   . TRP C 1 162 ? -61.011  -26.893 40.136  1.00 51.14  ? 222 TRP C N   1 
ATOM   9841  C CA  . TRP C 1 162 ? -61.461  -25.629 39.491  1.00 49.92  ? 222 TRP C CA  1 
ATOM   9842  C C   . TRP C 1 162 ? -61.444  -24.529 40.558  1.00 49.96  ? 222 TRP C C   1 
ATOM   9843  O O   . TRP C 1 162 ? -62.022  -24.683 41.635  1.00 46.49  ? 222 TRP C O   1 
ATOM   9844  C CB  . TRP C 1 162 ? -62.826  -25.797 38.811  1.00 49.36  ? 222 TRP C CB  1 
ATOM   9845  C CG  . TRP C 1 162 ? -63.220  -24.636 37.944  1.00 52.77  ? 222 TRP C CG  1 
ATOM   9846  C CD1 . TRP C 1 162 ? -64.016  -23.569 38.265  1.00 49.09  ? 222 TRP C CD1 1 
ATOM   9847  C CD2 . TRP C 1 162 ? -62.807  -24.420 36.585  1.00 53.62  ? 222 TRP C CD2 1 
ATOM   9848  N NE1 . TRP C 1 162 ? -64.132  -22.711 37.202  1.00 47.95  ? 222 TRP C NE1 1 
ATOM   9849  C CE2 . TRP C 1 162 ? -63.401  -23.204 36.157  1.00 48.95  ? 222 TRP C CE2 1 
ATOM   9850  C CE3 . TRP C 1 162 ? -62.026  -25.160 35.682  1.00 50.64  ? 222 TRP C CE3 1 
ATOM   9851  C CZ2 . TRP C 1 162 ? -63.190  -22.693 34.879  1.00 47.32  ? 222 TRP C CZ2 1 
ATOM   9852  C CZ3 . TRP C 1 162 ? -61.801  -24.637 34.424  1.00 48.20  ? 222 TRP C CZ3 1 
ATOM   9853  C CH2 . TRP C 1 162 ? -62.385  -23.426 34.030  1.00 48.87  ? 222 TRP C CH2 1 
ATOM   9854  N N   . PRO C 1 163 ? -60.784  -23.382 40.306  1.00 49.99  ? 223 PRO C N   1 
ATOM   9855  C CA  . PRO C 1 163 ? -60.537  -22.377 41.345  1.00 56.59  ? 223 PRO C CA  1 
ATOM   9856  C C   . PRO C 1 163 ? -61.656  -21.339 41.535  1.00 56.05  ? 223 PRO C C   1 
ATOM   9857  O O   . PRO C 1 163 ? -61.354  -20.240 41.970  1.00 57.29  ? 223 PRO C O   1 
ATOM   9858  C CB  . PRO C 1 163 ? -59.288  -21.684 40.795  1.00 52.19  ? 223 PRO C CB  1 
ATOM   9859  C CG  . PRO C 1 163 ? -59.575  -21.642 39.307  1.00 53.85  ? 223 PRO C CG  1 
ATOM   9860  C CD  . PRO C 1 163 ? -60.242  -22.977 39.011  1.00 52.48  ? 223 PRO C CD  1 
ATOM   9861  N N   . HIS C 1 164 ? -62.889  -21.695 41.151  1.00 56.99  ? 224 HIS C N   1 
ATOM   9862  C CA  . HIS C 1 164 ? -64.143  -20.957 41.451  1.00 56.69  ? 224 HIS C CA  1 
ATOM   9863  C C   . HIS C 1 164 ? -65.157  -21.962 42.023  1.00 62.21  ? 224 HIS C C   1 
ATOM   9864  O O   . HIS C 1 164 ? -65.423  -23.038 41.396  1.00 69.93  ? 224 HIS C O   1 
ATOM   9865  C CB  . HIS C 1 164 ? -64.667  -20.229 40.208  1.00 59.41  ? 224 HIS C CB  1 
ATOM   9866  C CG  . HIS C 1 164 ? -63.725  -19.261 39.578  1.00 61.94  ? 224 HIS C CG  1 
ATOM   9867  N ND1 . HIS C 1 164 ? -63.602  -17.955 40.017  1.00 64.88  ? 224 HIS C ND1 1 
ATOM   9868  C CD2 . HIS C 1 164 ? -62.854  -19.414 38.552  1.00 64.14  ? 224 HIS C CD2 1 
ATOM   9869  C CE1 . HIS C 1 164 ? -62.669  -17.344 39.295  1.00 72.98  ? 224 HIS C CE1 1 
ATOM   9870  N NE2 . HIS C 1 164 ? -62.212  -18.215 38.375  1.00 71.26  ? 224 HIS C NE2 1 
ATOM   9871  N N   . ARG C 1 165 ? -65.673  -21.643 43.205  1.00 64.91  ? 225 ARG C N   1 
ATOM   9872  C CA  . ARG C 1 165 ? -66.534  -22.515 44.050  1.00 74.23  ? 225 ARG C CA  1 
ATOM   9873  C C   . ARG C 1 165 ? -68.017  -22.310 43.664  1.00 75.63  ? 225 ARG C C   1 
ATOM   9874  O O   . ARG C 1 165 ? -68.765  -23.301 43.633  1.00 86.00  ? 225 ARG C O   1 
ATOM   9875  C CB  . ARG C 1 165 ? -66.233  -22.228 45.534  1.00 80.94  ? 225 ARG C CB  1 
ATOM   9876  C CG  . ARG C 1 165 ? -65.226  -21.095 45.825  1.00 96.15  ? 225 ARG C CG  1 
ATOM   9877  C CD  . ARG C 1 165 ? -65.683  -19.608 45.840  1.00 90.69  ? 225 ARG C CD  1 
ATOM   9878  N NE  . ARG C 1 165 ? -66.279  -19.079 44.601  1.00 77.87  ? 225 ARG C NE  1 
ATOM   9879  C CZ  . ARG C 1 165 ? -65.675  -18.356 43.665  1.00 59.73  ? 225 ARG C CZ  1 
ATOM   9880  N NH1 . ARG C 1 165 ? -64.425  -17.972 43.772  1.00 59.03  ? 225 ARG C NH1 1 
ATOM   9881  N NH2 . ARG C 1 165 ? -66.334  -18.030 42.579  1.00 60.13  ? 225 ARG C NH2 1 
ATOM   9882  N N   . ASN C 1 166 ? -68.402  -21.085 43.304  1.00 73.37  ? 226 ASN C N   1 
ATOM   9883  C CA  . ASN C 1 166 ? -69.800  -20.622 43.116  1.00 76.07  ? 226 ASN C CA  1 
ATOM   9884  C C   . ASN C 1 166 ? -70.193  -20.801 41.643  1.00 63.29  ? 226 ASN C C   1 
ATOM   9885  O O   . ASN C 1 166 ? -70.275  -19.794 40.895  1.00 57.22  ? 226 ASN C O   1 
ATOM   9886  C CB  . ASN C 1 166 ? -69.931  -19.169 43.587  1.00 94.24  ? 226 ASN C CB  1 
ATOM   9887  C CG  . ASN C 1 166 ? -71.359  -18.737 43.861  1.00 107.53 ? 226 ASN C CG  1 
ATOM   9888  O OD1 . ASN C 1 166 ? -72.291  -19.076 43.130  1.00 98.69  ? 226 ASN C OD1 1 
ATOM   9889  N ND2 . ASN C 1 166 ? -71.534  -17.962 44.923  1.00 140.41 ? 226 ASN C ND2 1 
ATOM   9890  N N   . ILE C 1 167 ? -70.453  -22.034 41.205  1.00 60.04  ? 227 ILE C N   1 
ATOM   9891  C CA  . ILE C 1 167 ? -70.805  -22.325 39.777  1.00 66.81  ? 227 ILE C CA  1 
ATOM   9892  C C   . ILE C 1 167 ? -72.331  -22.326 39.622  1.00 66.38  ? 227 ILE C C   1 
ATOM   9893  O O   . ILE C 1 167 ? -73.007  -23.037 40.410  1.00 65.69  ? 227 ILE C O   1 
ATOM   9894  C CB  . ILE C 1 167 ? -70.150  -23.646 39.325  1.00 63.30  ? 227 ILE C CB  1 
ATOM   9895  C CG1 . ILE C 1 167 ? -68.632  -23.498 39.256  1.00 65.29  ? 227 ILE C CG1 1 
ATOM   9896  C CG2 . ILE C 1 167 ? -70.708  -24.142 38.011  1.00 66.20  ? 227 ILE C CG2 1 
ATOM   9897  C CD1 . ILE C 1 167 ? -68.161  -22.256 38.512  1.00 64.91  ? 227 ILE C CD1 1 
ATOM   9898  N N   . GLN C 1 168 ? -72.838  -21.545 38.655  1.00 64.73  ? 228 GLN C N   1 
ATOM   9899  C CA  . GLN C 1 168 ? -74.289  -21.357 38.343  1.00 66.97  ? 228 GLN C CA  1 
ATOM   9900  C C   . GLN C 1 168 ? -74.657  -22.042 37.018  1.00 66.90  ? 228 GLN C C   1 
ATOM   9901  O O   . GLN C 1 168 ? -75.757  -22.615 36.956  1.00 69.51  ? 228 GLN C O   1 
ATOM   9902  C CB  . GLN C 1 168 ? -74.642  -19.866 38.280  1.00 67.82  ? 228 GLN C CB  1 
ATOM   9903  C CG  . GLN C 1 168 ? -74.570  -19.200 39.644  1.00 71.97  ? 228 GLN C CG  1 
ATOM   9904  C CD  . GLN C 1 168 ? -74.815  -17.716 39.664  1.00 73.85  ? 228 GLN C CD  1 
ATOM   9905  O OE1 . GLN C 1 168 ? -74.993  -17.042 38.649  1.00 79.83  ? 228 GLN C OE1 1 
ATOM   9906  N NE2 . GLN C 1 168 ? -74.849  -17.202 40.876  1.00 76.13  ? 228 GLN C NE2 1 
ATOM   9907  N N   . VAL C 1 169 ? -73.782  -21.941 36.004  1.00 64.29  ? 229 VAL C N   1 
ATOM   9908  C CA  . VAL C 1 169 ? -73.956  -22.532 34.645  1.00 54.43  ? 229 VAL C CA  1 
ATOM   9909  C C   . VAL C 1 169 ? -72.800  -23.486 34.343  1.00 44.19  ? 229 VAL C C   1 
ATOM   9910  O O   . VAL C 1 169 ? -71.656  -23.055 34.308  1.00 37.68  ? 229 VAL C O   1 
ATOM   9911  C CB  . VAL C 1 169 ? -74.046  -21.456 33.552  1.00 53.89  ? 229 VAL C CB  1 
ATOM   9912  C CG1 . VAL C 1 169 ? -74.395  -22.107 32.227  1.00 52.75  ? 229 VAL C CG1 1 
ATOM   9913  C CG2 . VAL C 1 169 ? -75.046  -20.357 33.892  1.00 51.32  ? 229 VAL C CG2 1 
ATOM   9914  N N   . ILE C 1 170 ? -73.116  -24.750 34.134  1.00 42.22  ? 230 ILE C N   1 
ATOM   9915  C CA  . ILE C 1 170 ? -72.183  -25.756 33.568  1.00 48.08  ? 230 ILE C CA  1 
ATOM   9916  C C   . ILE C 1 170 ? -72.624  -25.974 32.125  1.00 58.31  ? 230 ILE C C   1 
ATOM   9917  O O   . ILE C 1 170 ? -73.839  -25.957 31.892  1.00 71.99  ? 230 ILE C O   1 
ATOM   9918  C CB  . ILE C 1 170 ? -72.179  -27.068 34.373  1.00 45.47  ? 230 ILE C CB  1 
ATOM   9919  C CG1 . ILE C 1 170 ? -71.484  -26.879 35.721  1.00 47.17  ? 230 ILE C CG1 1 
ATOM   9920  C CG2 . ILE C 1 170 ? -71.563  -28.210 33.554  1.00 49.25  ? 230 ILE C CG2 1 
ATOM   9921  C CD1 . ILE C 1 170 ? -71.703  -27.998 36.739  1.00 45.45  ? 230 ILE C CD1 1 
ATOM   9922  N N   . CYS C 1 171 ? -71.671  -26.122 31.205  1.00 59.09  ? 231 CYS C N   1 
ATOM   9923  C CA  . CYS C 1 171 ? -71.931  -26.533 29.812  1.00 61.55  ? 231 CYS C CA  1 
ATOM   9924  C C   . CYS C 1 171 ? -71.040  -27.735 29.504  1.00 60.25  ? 231 CYS C C   1 
ATOM   9925  O O   . CYS C 1 171 ? -69.819  -27.613 29.598  1.00 62.26  ? 231 CYS C O   1 
ATOM   9926  C CB  . CYS C 1 171 ? -71.726  -25.365 28.860  1.00 64.81  ? 231 CYS C CB  1 
ATOM   9927  S SG  . CYS C 1 171 ? -72.593  -25.613 27.296  1.00 83.20  ? 231 CYS C SG  1 
ATOM   9928  N N   . VAL C 1 172 ? -71.635  -28.877 29.189  1.00 57.60  ? 232 VAL C N   1 
ATOM   9929  C CA  . VAL C 1 172 ? -70.906  -30.175 29.178  1.00 62.48  ? 232 VAL C CA  1 
ATOM   9930  C C   . VAL C 1 172 ? -71.216  -30.924 27.883  1.00 69.15  ? 232 VAL C C   1 
ATOM   9931  O O   . VAL C 1 172 ? -72.386  -30.952 27.515  1.00 79.46  ? 232 VAL C O   1 
ATOM   9932  C CB  . VAL C 1 172 ? -71.313  -31.028 30.384  1.00 67.23  ? 232 VAL C CB  1 
ATOM   9933  C CG1 . VAL C 1 172 ? -72.815  -31.237 30.446  1.00 78.47  ? 232 VAL C CG1 1 
ATOM   9934  C CG2 . VAL C 1 172 ? -70.607  -32.357 30.362  1.00 60.58  ? 232 VAL C CG2 1 
ATOM   9935  N N   . THR C 1 173 ? -70.209  -31.549 27.263  1.00 64.24  ? 233 THR C N   1 
ATOM   9936  C CA  . THR C 1 173 ? -70.336  -32.418 26.055  1.00 54.26  ? 233 THR C CA  1 
ATOM   9937  C C   . THR C 1 173 ? -69.556  -33.718 26.286  1.00 46.33  ? 233 THR C C   1 
ATOM   9938  O O   . THR C 1 173 ? -68.627  -33.706 27.105  1.00 45.11  ? 233 THR C O   1 
ATOM   9939  C CB  . THR C 1 173 ? -69.834  -31.704 24.795  1.00 47.97  ? 233 THR C CB  1 
ATOM   9940  O OG1 . THR C 1 173 ? -69.766  -32.677 23.764  1.00 59.92  ? 233 THR C OG1 1 
ATOM   9941  C CG2 . THR C 1 173 ? -68.454  -31.129 24.916  1.00 47.88  ? 233 THR C CG2 1 
ATOM   9942  N N   . ASP C 1 174 ? -69.915  -34.813 25.625  1.00 43.56  ? 234 ASP C N   1 
ATOM   9943  C CA  . ASP C 1 174 ? -69.037  -36.011 25.633  1.00 47.87  ? 234 ASP C CA  1 
ATOM   9944  C C   . ASP C 1 174 ? -68.410  -36.143 24.252  1.00 46.33  ? 234 ASP C C   1 
ATOM   9945  O O   . ASP C 1 174 ? -67.684  -37.132 24.018  1.00 45.46  ? 234 ASP C O   1 
ATOM   9946  C CB  . ASP C 1 174 ? -69.740  -37.274 26.128  1.00 49.94  ? 234 ASP C CB  1 
ATOM   9947  C CG  . ASP C 1 174 ? -70.664  -37.891 25.119  1.00 52.96  ? 234 ASP C CG  1 
ATOM   9948  O OD1 . ASP C 1 174 ? -70.972  -37.181 24.153  1.00 57.00  ? 234 ASP C OD1 1 
ATOM   9949  O OD2 . ASP C 1 174 ? -71.058  -39.070 25.328  1.00 61.81  ? 234 ASP C OD2 1 
ATOM   9950  N N   . GLY C 1 175 ? -68.652  -35.140 23.409  1.00 47.30  ? 235 GLY C N   1 
ATOM   9951  C CA  . GLY C 1 175 ? -68.004  -34.944 22.101  1.00 45.50  ? 235 GLY C CA  1 
ATOM   9952  C C   . GLY C 1 175 ? -68.571  -35.832 21.002  1.00 51.00  ? 235 GLY C C   1 
ATOM   9953  O O   . GLY C 1 175 ? -68.001  -35.794 19.890  1.00 60.13  ? 235 GLY C O   1 
ATOM   9954  N N   . GLU C 1 176 ? -69.640  -36.602 21.259  1.00 56.61  ? 236 GLU C N   1 
ATOM   9955  C CA  . GLU C 1 176 ? -70.117  -37.677 20.336  1.00 55.11  ? 236 GLU C CA  1 
ATOM   9956  C C   . GLU C 1 176 ? -70.711  -37.103 19.045  1.00 51.69  ? 236 GLU C C   1 
ATOM   9957  O O   . GLU C 1 176 ? -70.581  -37.795 18.015  1.00 49.33  ? 236 GLU C O   1 
ATOM   9958  C CB  . GLU C 1 176 ? -71.124  -38.623 20.983  1.00 59.35  ? 236 GLU C CB  1 
ATOM   9959  C CG  . GLU C 1 176 ? -71.353  -39.867 20.135  1.00 62.06  ? 236 GLU C CG  1 
ATOM   9960  C CD  . GLU C 1 176 ? -71.705  -41.110 20.930  1.00 65.80  ? 236 GLU C CD  1 
ATOM   9961  O OE1 . GLU C 1 176 ? -72.220  -40.939 22.070  1.00 66.63  ? 236 GLU C OE1 1 
ATOM   9962  O OE2 . GLU C 1 176 ? -71.486  -42.247 20.399  1.00 59.76  ? 236 GLU C OE2 1 
ATOM   9963  N N   . ARG C 1 177 ? -71.355  -35.930 19.079  1.00 50.40  ? 237 ARG C N   1 
ATOM   9964  C CA  . ARG C 1 177 ? -71.959  -35.322 17.858  1.00 57.07  ? 237 ARG C CA  1 
ATOM   9965  C C   . ARG C 1 177 ? -71.686  -33.822 17.840  1.00 57.86  ? 237 ARG C C   1 
ATOM   9966  O O   . ARG C 1 177 ? -72.619  -33.060 18.027  1.00 68.92  ? 237 ARG C O   1 
ATOM   9967  C CB  . ARG C 1 177 ? -73.468  -35.568 17.797  1.00 59.71  ? 237 ARG C CB  1 
ATOM   9968  C CG  . ARG C 1 177 ? -73.872  -37.013 17.582  1.00 62.47  ? 237 ARG C CG  1 
ATOM   9969  C CD  . ARG C 1 177 ? -73.401  -37.539 16.247  1.00 67.29  ? 237 ARG C CD  1 
ATOM   9970  N NE  . ARG C 1 177 ? -72.839  -38.876 16.407  1.00 74.32  ? 237 ARG C NE  1 
ATOM   9971  C CZ  . ARG C 1 177 ? -73.510  -40.015 16.224  1.00 100.30 ? 237 ARG C CZ  1 
ATOM   9972  N NH1 . ARG C 1 177 ? -74.787  -40.017 15.846  1.00 112.84 ? 237 ARG C NH1 1 
ATOM   9973  N NH2 . ARG C 1 177 ? -72.880  -41.164 16.393  1.00 104.70 ? 237 ARG C NH2 1 
ATOM   9974  N N   . ILE C 1 178 ? -70.444  -33.415 17.608  1.00 57.78  ? 238 ILE C N   1 
ATOM   9975  C CA  . ILE C 1 178 ? -70.071  -31.970 17.597  1.00 55.18  ? 238 ILE C CA  1 
ATOM   9976  C C   . ILE C 1 178 ? -70.630  -31.341 16.322  1.00 49.55  ? 238 ILE C C   1 
ATOM   9977  O O   . ILE C 1 178 ? -70.200  -31.759 15.243  1.00 54.67  ? 238 ILE C O   1 
ATOM   9978  C CB  . ILE C 1 178 ? -68.544  -31.806 17.697  1.00 54.61  ? 238 ILE C CB  1 
ATOM   9979  C CG1 . ILE C 1 178 ? -68.001  -32.406 18.997  1.00 49.77  ? 238 ILE C CG1 1 
ATOM   9980  C CG2 . ILE C 1 178 ? -68.152  -30.339 17.499  1.00 57.58  ? 238 ILE C CG2 1 
ATOM   9981  C CD1 . ILE C 1 178 ? -68.555  -31.785 20.260  1.00 51.40  ? 238 ILE C CD1 1 
ATOM   9982  N N   . LEU C 1 179 ? -71.571  -30.410 16.442  1.00 51.26  ? 239 LEU C N   1 
ATOM   9983  C CA  . LEU C 1 179 ? -72.295  -29.801 15.284  1.00 56.87  ? 239 LEU C CA  1 
ATOM   9984  C C   . LEU C 1 179 ? -72.771  -30.948 14.365  1.00 57.26  ? 239 LEU C C   1 
ATOM   9985  O O   . LEU C 1 179 ? -73.163  -31.998 14.894  1.00 61.68  ? 239 LEU C O   1 
ATOM   9986  C CB  . LEU C 1 179 ? -71.374  -28.798 14.566  1.00 55.06  ? 239 LEU C CB  1 
ATOM   9987  C CG  . LEU C 1 179 ? -70.981  -27.576 15.388  1.00 52.87  ? 239 LEU C CG  1 
ATOM   9988  C CD1 . LEU C 1 179 ? -69.976  -26.742 14.635  1.00 55.90  ? 239 LEU C CD1 1 
ATOM   9989  C CD2 . LEU C 1 179 ? -72.198  -26.739 15.732  1.00 59.09  ? 239 LEU C CD2 1 
ATOM   9990  N N   . GLY C 1 180 ? -72.715  -30.786 13.037  1.00 54.19  ? 240 GLY C N   1 
ATOM   9991  C CA  . GLY C 1 180 ? -72.953  -31.875 12.078  1.00 52.49  ? 240 GLY C CA  1 
ATOM   9992  C C   . GLY C 1 180 ? -71.680  -32.611 11.677  1.00 54.91  ? 240 GLY C C   1 
ATOM   9993  O O   . GLY C 1 180 ? -71.707  -33.234 10.601  1.00 62.74  ? 240 GLY C O   1 
ATOM   9994  N N   . LEU C 1 181 ? -70.608  -32.564 12.482  1.00 53.17  ? 241 LEU C N   1 
ATOM   9995  C CA  . LEU C 1 181 ? -69.259  -33.085 12.117  1.00 51.90  ? 241 LEU C CA  1 
ATOM   9996  C C   . LEU C 1 181 ? -68.994  -34.465 12.742  1.00 53.08  ? 241 LEU C C   1 
ATOM   9997  O O   . LEU C 1 181 ? -67.885  -35.015 12.514  1.00 51.92  ? 241 LEU C O   1 
ATOM   9998  C CB  . LEU C 1 181 ? -68.213  -32.071 12.571  1.00 49.72  ? 241 LEU C CB  1 
ATOM   9999  C CG  . LEU C 1 181 ? -68.410  -30.661 12.035  1.00 53.45  ? 241 LEU C CG  1 
ATOM   10000 C CD1 . LEU C 1 181 ? -67.395  -29.691 12.628  1.00 56.11  ? 241 LEU C CD1 1 
ATOM   10001 C CD2 . LEU C 1 181 ? -68.292  -30.651 10.531  1.00 58.90  ? 241 LEU C CD2 1 
ATOM   10002 N N   . GLY C 1 182 ? -69.948  -35.010 13.493  1.00 51.61  ? 242 GLY C N   1 
ATOM   10003 C CA  . GLY C 1 182 ? -69.792  -36.327 14.130  1.00 55.69  ? 242 GLY C CA  1 
ATOM   10004 C C   . GLY C 1 182 ? -68.916  -36.281 15.390  1.00 65.13  ? 242 GLY C C   1 
ATOM   10005 O O   . GLY C 1 182 ? -68.862  -35.224 16.113  1.00 63.65  ? 242 GLY C O   1 
ATOM   10006 N N   . ASP C 1 183 ? -68.233  -37.405 15.634  1.00 63.46  ? 243 ASP C N   1 
ATOM   10007 C CA  . ASP C 1 183 ? -67.484  -37.754 16.876  1.00 59.64  ? 243 ASP C CA  1 
ATOM   10008 C C   . ASP C 1 183 ? -66.083  -37.108 16.850  1.00 63.38  ? 243 ASP C C   1 
ATOM   10009 O O   . ASP C 1 183 ? -65.216  -37.542 16.054  1.00 63.07  ? 243 ASP C O   1 
ATOM   10010 C CB  . ASP C 1 183 ? -67.421  -39.278 16.986  1.00 59.43  ? 243 ASP C CB  1 
ATOM   10011 C CG  . ASP C 1 183 ? -66.926  -39.805 18.314  1.00 59.87  ? 243 ASP C CG  1 
ATOM   10012 O OD1 . ASP C 1 183 ? -66.307  -39.017 19.069  1.00 46.94  ? 243 ASP C OD1 1 
ATOM   10013 O OD2 . ASP C 1 183 ? -67.184  -41.019 18.579  1.00 68.86  ? 243 ASP C OD2 1 
ATOM   10014 N N   . LEU C 1 184 ? -65.850  -36.099 17.684  1.00 61.71  ? 244 LEU C N   1 
ATOM   10015 C CA  . LEU C 1 184 ? -64.512  -35.457 17.826  1.00 59.42  ? 244 LEU C CA  1 
ATOM   10016 C C   . LEU C 1 184 ? -63.979  -35.756 19.229  1.00 56.45  ? 244 LEU C C   1 
ATOM   10017 O O   . LEU C 1 184 ? -63.047  -35.054 19.695  1.00 70.80  ? 244 LEU C O   1 
ATOM   10018 C CB  . LEU C 1 184 ? -64.616  -33.953 17.543  1.00 55.71  ? 244 LEU C CB  1 
ATOM   10019 C CG  . LEU C 1 184 ? -64.985  -33.603 16.108  1.00 51.72  ? 244 LEU C CG  1 
ATOM   10020 C CD1 . LEU C 1 184 ? -65.029  -32.097 15.903  1.00 52.32  ? 244 LEU C CD1 1 
ATOM   10021 C CD2 . LEU C 1 184 ? -64.021  -34.277 15.156  1.00 54.02  ? 244 LEU C CD2 1 
ATOM   10022 N N   . GLY C 1 185 ? -64.538  -36.783 19.866  1.00 54.57  ? 245 GLY C N   1 
ATOM   10023 C CA  . GLY C 1 185 ? -64.119  -37.200 21.215  1.00 58.05  ? 245 GLY C CA  1 
ATOM   10024 C C   . GLY C 1 185 ? -63.774  -35.991 22.070  1.00 51.67  ? 245 GLY C C   1 
ATOM   10025 O O   . GLY C 1 185 ? -64.511  -34.984 22.036  1.00 41.85  ? 245 GLY C O   1 
ATOM   10026 N N   . CYS C 1 186 ? -62.630  -36.063 22.737  1.00 51.81  ? 246 CYS C N   1 
ATOM   10027 C CA  . CYS C 1 186 ? -62.202  -35.107 23.784  1.00 53.56  ? 246 CYS C CA  1 
ATOM   10028 C C   . CYS C 1 186 ? -61.995  -33.696 23.197  1.00 53.23  ? 246 CYS C C   1 
ATOM   10029 O O   . CYS C 1 186 ? -61.945  -32.709 23.990  1.00 48.31  ? 246 CYS C O   1 
ATOM   10030 C CB  . CYS C 1 186 ? -60.932  -35.615 24.435  1.00 53.02  ? 246 CYS C CB  1 
ATOM   10031 S SG  . CYS C 1 186 ? -60.711  -34.952 26.095  1.00 61.25  ? 246 CYS C SG  1 
ATOM   10032 N N   . GLN C 1 187 ? -61.904  -33.572 21.872  1.00 46.16  ? 247 GLN C N   1 
ATOM   10033 C CA  . GLN C 1 187 ? -61.651  -32.259 21.231  1.00 56.02  ? 247 GLN C CA  1 
ATOM   10034 C C   . GLN C 1 187 ? -62.977  -31.488 21.098  1.00 59.95  ? 247 GLN C C   1 
ATOM   10035 O O   . GLN C 1 187 ? -62.969  -30.346 20.567  1.00 66.37  ? 247 GLN C O   1 
ATOM   10036 C CB  . GLN C 1 187 ? -60.903  -32.453 19.904  1.00 63.91  ? 247 GLN C CB  1 
ATOM   10037 C CG  . GLN C 1 187 ? -59.502  -33.042 20.065  1.00 61.37  ? 247 GLN C CG  1 
ATOM   10038 C CD  . GLN C 1 187 ? -58.654  -32.958 18.826  1.00 58.72  ? 247 GLN C CD  1 
ATOM   10039 O OE1 . GLN C 1 187 ? -59.068  -32.403 17.810  1.00 57.64  ? 247 GLN C OE1 1 
ATOM   10040 N NE2 . GLN C 1 187 ? -57.464  -33.529 18.903  1.00 61.81  ? 247 GLN C NE2 1 
ATOM   10041 N N   . GLY C 1 188 ? -64.080  -32.062 21.584  1.00 57.66  ? 248 GLY C N   1 
ATOM   10042 C CA  . GLY C 1 188 ? -65.398  -31.394 21.642  1.00 54.98  ? 248 GLY C CA  1 
ATOM   10043 C C   . GLY C 1 188 ? -65.385  -30.140 22.504  1.00 46.23  ? 248 GLY C C   1 
ATOM   10044 O O   . GLY C 1 188 ? -66.308  -29.314 22.384  1.00 45.53  ? 248 GLY C O   1 
ATOM   10045 N N   . MET C 1 189 ? -64.376  -29.979 23.345  1.00 46.22  ? 249 MET C N   1 
ATOM   10046 C CA  . MET C 1 189 ? -64.314  -28.881 24.343  1.00 60.86  ? 249 MET C CA  1 
ATOM   10047 C C   . MET C 1 189 ? -64.561  -27.503 23.681  1.00 57.41  ? 249 MET C C   1 
ATOM   10048 O O   . MET C 1 189 ? -64.970  -26.576 24.380  1.00 64.91  ? 249 MET C O   1 
ATOM   10049 C CB  . MET C 1 189 ? -62.962  -28.899 25.078  1.00 60.74  ? 249 MET C CB  1 
ATOM   10050 C CG  . MET C 1 189 ? -62.790  -27.786 26.111  1.00 55.08  ? 249 MET C CG  1 
ATOM   10051 S SD  . MET C 1 189 ? -63.994  -27.870 27.448  1.00 56.64  ? 249 MET C SD  1 
ATOM   10052 C CE  . MET C 1 189 ? -63.021  -28.733 28.695  1.00 70.74  ? 249 MET C CE  1 
ATOM   10053 N N   . GLY C 1 190 ? -64.330  -27.338 22.385  1.00 53.15  ? 250 GLY C N   1 
ATOM   10054 C CA  . GLY C 1 190 ? -64.456  -26.017 21.745  1.00 56.04  ? 250 GLY C CA  1 
ATOM   10055 C C   . GLY C 1 190 ? -65.848  -25.452 21.921  1.00 55.09  ? 250 GLY C C   1 
ATOM   10056 O O   . GLY C 1 190 ? -65.978  -24.201 22.028  1.00 61.33  ? 250 GLY C O   1 
ATOM   10057 N N   . ILE C 1 191 ? -66.830  -26.356 21.956  1.00 55.58  ? 251 ILE C N   1 
ATOM   10058 C CA  . ILE C 1 191 ? -68.297  -26.075 22.004  1.00 60.00  ? 251 ILE C CA  1 
ATOM   10059 C C   . ILE C 1 191 ? -68.653  -25.522 23.385  1.00 50.58  ? 251 ILE C C   1 
ATOM   10060 O O   . ILE C 1 191 ? -69.061  -24.371 23.517  1.00 41.94  ? 251 ILE C O   1 
ATOM   10061 C CB  . ILE C 1 191 ? -69.099  -27.352 21.615  1.00 62.37  ? 251 ILE C CB  1 
ATOM   10062 C CG1 . ILE C 1 191 ? -68.849  -27.783 20.162  1.00 53.55  ? 251 ILE C CG1 1 
ATOM   10063 C CG2 . ILE C 1 191 ? -70.587  -27.174 21.888  1.00 66.78  ? 251 ILE C CG2 1 
ATOM   10064 C CD1 . ILE C 1 191 ? -69.167  -26.671 19.142  1.00 51.00  ? 251 ILE C CD1 1 
ATOM   10065 N N   . PRO C 1 192 ? -68.516  -26.309 24.471  1.00 52.85  ? 252 PRO C N   1 
ATOM   10066 C CA  . PRO C 1 192 ? -68.818  -25.797 25.803  1.00 56.77  ? 252 PRO C CA  1 
ATOM   10067 C C   . PRO C 1 192 ? -68.155  -24.443 26.051  1.00 49.37  ? 252 PRO C C   1 
ATOM   10068 O O   . PRO C 1 192 ? -68.804  -23.589 26.623  1.00 58.19  ? 252 PRO C O   1 
ATOM   10069 C CB  . PRO C 1 192 ? -68.268  -26.869 26.748  1.00 52.66  ? 252 PRO C CB  1 
ATOM   10070 C CG  . PRO C 1 192 ? -68.332  -28.141 25.937  1.00 53.56  ? 252 PRO C CG  1 
ATOM   10071 C CD  . PRO C 1 192 ? -68.110  -27.723 24.504  1.00 51.52  ? 252 PRO C CD  1 
ATOM   10072 N N   . VAL C 1 193 ? -66.914  -24.280 25.612  1.00 46.69  ? 253 VAL C N   1 
ATOM   10073 C CA  . VAL C 1 193 ? -66.152  -23.021 25.874  1.00 57.67  ? 253 VAL C CA  1 
ATOM   10074 C C   . VAL C 1 193 ? -66.827  -21.902 25.072  1.00 55.06  ? 253 VAL C C   1 
ATOM   10075 O O   . VAL C 1 193 ? -66.972  -20.770 25.566  1.00 50.00  ? 253 VAL C O   1 
ATOM   10076 C CB  . VAL C 1 193 ? -64.639  -23.131 25.581  1.00 54.78  ? 253 VAL C CB  1 
ATOM   10077 C CG1 . VAL C 1 193 ? -63.976  -21.790 25.838  1.00 56.05  ? 253 VAL C CG1 1 
ATOM   10078 C CG2 . VAL C 1 193 ? -63.952  -24.207 26.433  1.00 50.19  ? 253 VAL C CG2 1 
ATOM   10079 N N   . GLY C 1 194 ? -67.285  -22.243 23.885  1.00 54.18  ? 254 GLY C N   1 
ATOM   10080 C CA  . GLY C 1 194 ? -67.974  -21.292 23.003  1.00 55.09  ? 254 GLY C CA  1 
ATOM   10081 C C   . GLY C 1 194 ? -69.286  -20.859 23.596  1.00 55.44  ? 254 GLY C C   1 
ATOM   10082 O O   . GLY C 1 194 ? -69.493  -19.638 23.758  1.00 62.86  ? 254 GLY C O   1 
ATOM   10083 N N   . LYS C 1 195 ? -70.144  -21.834 23.907  1.00 50.53  ? 255 LYS C N   1 
ATOM   10084 C CA  . LYS C 1 195 ? -71.501  -21.576 24.435  1.00 43.78  ? 255 LYS C CA  1 
ATOM   10085 C C   . LYS C 1 195 ? -71.368  -20.611 25.614  1.00 46.62  ? 255 LYS C C   1 
ATOM   10086 O O   . LYS C 1 195 ? -72.022  -19.562 25.615  1.00 43.72  ? 255 LYS C O   1 
ATOM   10087 C CB  . LYS C 1 195 ? -72.130  -22.884 24.888  1.00 44.08  ? 255 LYS C CB  1 
ATOM   10088 C CG  . LYS C 1 195 ? -72.427  -23.894 23.786  1.00 50.77  ? 255 LYS C CG  1 
ATOM   10089 C CD  . LYS C 1 195 ? -73.647  -23.603 22.928  1.00 46.29  ? 255 LYS C CD  1 
ATOM   10090 C CE  . LYS C 1 195 ? -73.647  -24.458 21.679  1.00 49.28  ? 255 LYS C CE  1 
ATOM   10091 N NZ  . LYS C 1 195 ? -74.892  -24.289 20.890  1.00 59.58  ? 255 LYS C NZ  1 
ATOM   10092 N N   . LEU C 1 196 ? -70.479  -20.937 26.554  1.00 47.93  ? 256 LEU C N   1 
ATOM   10093 C CA  . LEU C 1 196 ? -70.367  -20.232 27.845  1.00 45.43  ? 256 LEU C CA  1 
ATOM   10094 C C   . LEU C 1 196 ? -69.839  -18.813 27.635  1.00 45.51  ? 256 LEU C C   1 
ATOM   10095 O O   . LEU C 1 196 ? -70.283  -17.923 28.347  1.00 45.89  ? 256 LEU C O   1 
ATOM   10096 C CB  . LEU C 1 196 ? -69.510  -21.080 28.774  1.00 47.45  ? 256 LEU C CB  1 
ATOM   10097 C CG  . LEU C 1 196 ? -70.210  -22.323 29.331  1.00 53.04  ? 256 LEU C CG  1 
ATOM   10098 C CD1 . LEU C 1 196 ? -69.271  -23.106 30.264  1.00 60.46  ? 256 LEU C CD1 1 
ATOM   10099 C CD2 . LEU C 1 196 ? -71.497  -21.940 30.058  1.00 49.32  ? 256 LEU C CD2 1 
ATOM   10100 N N   . ALA C 1 197 ? -68.978  -18.588 26.654  1.00 50.67  ? 257 ALA C N   1 
ATOM   10101 C CA  . ALA C 1 197 ? -68.533  -17.226 26.277  1.00 52.81  ? 257 ALA C CA  1 
ATOM   10102 C C   . ALA C 1 197 ? -69.772  -16.439 25.860  1.00 55.11  ? 257 ALA C C   1 
ATOM   10103 O O   . ALA C 1 197 ? -69.862  -15.238 26.186  1.00 62.29  ? 257 ALA C O   1 
ATOM   10104 C CB  . ALA C 1 197 ? -67.510  -17.278 25.168  1.00 50.64  ? 257 ALA C CB  1 
ATOM   10105 N N   . LEU C 1 198 ? -70.699  -17.102 25.167  1.00 55.61  ? 258 LEU C N   1 
ATOM   10106 C CA  . LEU C 1 198 ? -71.933  -16.463 24.631  1.00 58.43  ? 258 LEU C CA  1 
ATOM   10107 C C   . LEU C 1 198 ? -72.877  -16.194 25.806  1.00 51.67  ? 258 LEU C C   1 
ATOM   10108 O O   . LEU C 1 198 ? -73.470  -15.112 25.866  1.00 48.78  ? 258 LEU C O   1 
ATOM   10109 C CB  . LEU C 1 198 ? -72.571  -17.360 23.562  1.00 63.82  ? 258 LEU C CB  1 
ATOM   10110 C CG  . LEU C 1 198 ? -72.210  -17.038 22.111  1.00 65.03  ? 258 LEU C CG  1 
ATOM   10111 C CD1 . LEU C 1 198 ? -70.716  -17.041 21.887  1.00 68.48  ? 258 LEU C CD1 1 
ATOM   10112 C CD2 . LEU C 1 198 ? -72.881  -18.003 21.146  1.00 62.74  ? 258 LEU C CD2 1 
ATOM   10113 N N   . TYR C 1 199 ? -72.974  -17.144 26.727  1.00 46.56  ? 259 TYR C N   1 
ATOM   10114 C CA  . TYR C 1 199 ? -73.754  -16.979 27.967  1.00 44.85  ? 259 TYR C CA  1 
ATOM   10115 C C   . TYR C 1 199 ? -73.403  -15.637 28.593  1.00 47.26  ? 259 TYR C C   1 
ATOM   10116 O O   . TYR C 1 199 ? -74.292  -15.038 29.233  1.00 51.90  ? 259 TYR C O   1 
ATOM   10117 C CB  . TYR C 1 199 ? -73.448  -18.088 28.967  1.00 45.99  ? 259 TYR C CB  1 
ATOM   10118 C CG  . TYR C 1 199 ? -74.522  -19.129 29.060  1.00 48.94  ? 259 TYR C CG  1 
ATOM   10119 C CD1 . TYR C 1 199 ? -75.692  -18.883 29.758  1.00 44.89  ? 259 TYR C CD1 1 
ATOM   10120 C CD2 . TYR C 1 199 ? -74.356  -20.370 28.455  1.00 56.93  ? 259 TYR C CD2 1 
ATOM   10121 C CE1 . TYR C 1 199 ? -76.684  -19.842 29.829  1.00 47.56  ? 259 TYR C CE1 1 
ATOM   10122 C CE2 . TYR C 1 199 ? -75.331  -21.349 28.533  1.00 53.94  ? 259 TYR C CE2 1 
ATOM   10123 C CZ  . TYR C 1 199 ? -76.498  -21.080 29.224  1.00 51.74  ? 259 TYR C CZ  1 
ATOM   10124 O OH  . TYR C 1 199 ? -77.435  -22.065 29.280  1.00 56.24  ? 259 TYR C OH  1 
ATOM   10125 N N   . THR C 1 200 ? -72.139  -15.213 28.471  1.00 47.94  ? 260 THR C N   1 
ATOM   10126 C CA  . THR C 1 200 ? -71.631  -13.976 29.118  1.00 57.96  ? 260 THR C CA  1 
ATOM   10127 C C   . THR C 1 200 ? -71.869  -12.789 28.179  1.00 56.64  ? 260 THR C C   1 
ATOM   10128 O O   . THR C 1 200 ? -72.382  -11.729 28.651  1.00 59.97  ? 260 THR C O   1 
ATOM   10129 C CB  . THR C 1 200 ? -70.138  -14.084 29.486  1.00 64.63  ? 260 THR C CB  1 
ATOM   10130 O OG1 . THR C 1 200 ? -69.959  -15.185 30.397  1.00 63.10  ? 260 THR C OG1 1 
ATOM   10131 C CG2 . THR C 1 200 ? -69.589  -12.788 30.069  1.00 63.77  ? 260 THR C CG2 1 
ATOM   10132 N N   . ALA C 1 201 ? -71.462  -12.939 26.923  1.00 46.28  ? 261 ALA C N   1 
ATOM   10133 C CA  . ALA C 1 201 ? -71.485  -11.857 25.926  1.00 54.05  ? 261 ALA C CA  1 
ATOM   10134 C C   . ALA C 1 201 ? -72.940  -11.520 25.577  1.00 59.52  ? 261 ALA C C   1 
ATOM   10135 O O   . ALA C 1 201 ? -73.277  -10.306 25.575  1.00 59.16  ? 261 ALA C O   1 
ATOM   10136 C CB  . ALA C 1 201 ? -70.696  -12.279 24.717  1.00 58.23  ? 261 ALA C CB  1 
ATOM   10137 N N   . LEU C 1 202 ? -73.780  -12.543 25.342  1.00 62.28  ? 262 LEU C N   1 
ATOM   10138 C CA  . LEU C 1 202 ? -75.181  -12.395 24.851  1.00 62.31  ? 262 LEU C CA  1 
ATOM   10139 C C   . LEU C 1 202 ? -76.151  -12.298 26.029  1.00 66.07  ? 262 LEU C C   1 
ATOM   10140 O O   . LEU C 1 202 ? -77.106  -11.517 25.912  1.00 78.91  ? 262 LEU C O   1 
ATOM   10141 C CB  . LEU C 1 202 ? -75.562  -13.590 23.969  1.00 67.01  ? 262 LEU C CB  1 
ATOM   10142 C CG  . LEU C 1 202 ? -74.598  -13.965 22.841  1.00 70.06  ? 262 LEU C CG  1 
ATOM   10143 C CD1 . LEU C 1 202 ? -75.163  -15.087 22.001  1.00 73.68  ? 262 LEU C CD1 1 
ATOM   10144 C CD2 . LEU C 1 202 ? -74.274  -12.776 21.952  1.00 68.26  ? 262 LEU C CD2 1 
ATOM   10145 N N   . GLY C 1 203 ? -75.936  -13.084 27.092  1.00 60.62  ? 263 GLY C N   1 
ATOM   10146 C CA  . GLY C 1 203 ? -76.864  -13.223 28.231  1.00 55.72  ? 263 GLY C CA  1 
ATOM   10147 C C   . GLY C 1 203 ? -76.545  -12.339 29.433  1.00 54.99  ? 263 GLY C C   1 
ATOM   10148 O O   . GLY C 1 203 ? -77.479  -12.022 30.193  1.00 57.35  ? 263 GLY C O   1 
ATOM   10149 N N   . GLY C 1 204 ? -75.273  -12.011 29.670  1.00 59.44  ? 264 GLY C N   1 
ATOM   10150 C CA  . GLY C 1 204 ? -74.834  -11.209 30.833  1.00 58.05  ? 264 GLY C CA  1 
ATOM   10151 C C   . GLY C 1 204 ? -74.567  -12.045 32.083  1.00 57.44  ? 264 GLY C C   1 
ATOM   10152 O O   . GLY C 1 204 ? -74.342  -11.431 33.134  1.00 58.03  ? 264 GLY C O   1 
ATOM   10153 N N   . VAL C 1 205 ? -74.535  -13.382 31.983  1.00 47.17  ? 265 VAL C N   1 
ATOM   10154 C CA  . VAL C 1 205 ? -74.053  -14.271 33.082  1.00 46.89  ? 265 VAL C CA  1 
ATOM   10155 C C   . VAL C 1 205 ? -72.598  -13.879 33.390  1.00 45.60  ? 265 VAL C C   1 
ATOM   10156 O O   . VAL C 1 205 ? -71.844  -13.748 32.451  1.00 49.45  ? 265 VAL C O   1 
ATOM   10157 C CB  . VAL C 1 205 ? -74.159  -15.751 32.647  1.00 45.43  ? 265 VAL C CB  1 
ATOM   10158 C CG1 . VAL C 1 205 ? -73.760  -16.754 33.714  1.00 38.42  ? 265 VAL C CG1 1 
ATOM   10159 C CG2 . VAL C 1 205 ? -75.534  -16.060 32.101  1.00 46.25  ? 265 VAL C CG2 1 
ATOM   10160 N N   . ASP C 1 206 ? -72.202  -13.726 34.649  1.00 51.56  ? 266 ASP C N   1 
ATOM   10161 C CA  . ASP C 1 206 ? -70.771  -13.522 35.023  1.00 64.14  ? 266 ASP C CA  1 
ATOM   10162 C C   . ASP C 1 206 ? -69.903  -14.697 34.530  1.00 60.86  ? 266 ASP C C   1 
ATOM   10163 O O   . ASP C 1 206 ? -70.282  -15.870 34.606  1.00 50.05  ? 266 ASP C O   1 
ATOM   10164 C CB  . ASP C 1 206 ? -70.628  -13.317 36.534  1.00 68.69  ? 266 ASP C CB  1 
ATOM   10165 C CG  . ASP C 1 206 ? -69.246  -12.850 36.954  1.00 71.54  ? 266 ASP C CG  1 
ATOM   10166 O OD1 . ASP C 1 206 ? -68.248  -13.401 36.466  1.00 80.46  ? 266 ASP C OD1 1 
ATOM   10167 O OD2 . ASP C 1 206 ? -69.182  -11.950 37.798  1.00 73.97  ? 266 ASP C OD2 1 
ATOM   10168 N N   . PRO C 1 207 ? -68.702  -14.429 33.966  1.00 62.45  ? 267 PRO C N   1 
ATOM   10169 C CA  . PRO C 1 207 ? -67.856  -15.520 33.471  1.00 61.31  ? 267 PRO C CA  1 
ATOM   10170 C C   . PRO C 1 207 ? -67.474  -16.501 34.583  1.00 55.33  ? 267 PRO C C   1 
ATOM   10171 O O   . PRO C 1 207 ? -67.377  -17.681 34.304  1.00 54.33  ? 267 PRO C O   1 
ATOM   10172 C CB  . PRO C 1 207 ? -66.606  -14.813 32.922  1.00 61.27  ? 267 PRO C CB  1 
ATOM   10173 C CG  . PRO C 1 207 ? -67.030  -13.363 32.665  1.00 58.42  ? 267 PRO C CG  1 
ATOM   10174 C CD  . PRO C 1 207 ? -68.145  -13.088 33.664  1.00 56.31  ? 267 PRO C CD  1 
ATOM   10175 N N   . SER C 1 208 ? -67.280  -15.984 35.796  1.00 52.76  ? 268 SER C N   1 
ATOM   10176 C CA  . SER C 1 208 ? -66.652  -16.730 36.915  1.00 52.98  ? 268 SER C CA  1 
ATOM   10177 C C   . SER C 1 208 ? -67.561  -17.863 37.377  1.00 47.83  ? 268 SER C C   1 
ATOM   10178 O O   . SER C 1 208 ? -67.041  -18.795 37.979  1.00 48.32  ? 268 SER C O   1 
ATOM   10179 C CB  . SER C 1 208 ? -66.256  -15.838 38.060  1.00 51.65  ? 268 SER C CB  1 
ATOM   10180 O OG  . SER C 1 208 ? -67.037  -14.675 38.105  1.00 56.14  ? 268 SER C OG  1 
ATOM   10181 N N   . VAL C 1 209 ? -68.854  -17.780 37.064  1.00 49.56  ? 269 VAL C N   1 
ATOM   10182 C CA  . VAL C 1 209 ? -69.875  -18.756 37.538  1.00 52.54  ? 269 VAL C CA  1 
ATOM   10183 C C   . VAL C 1 209 ? -70.099  -19.803 36.446  1.00 53.29  ? 269 VAL C C   1 
ATOM   10184 O O   . VAL C 1 209 ? -70.891  -20.715 36.730  1.00 47.41  ? 269 VAL C O   1 
ATOM   10185 C CB  . VAL C 1 209 ? -71.183  -18.056 37.953  1.00 56.94  ? 269 VAL C CB  1 
ATOM   10186 C CG1 . VAL C 1 209 ? -70.937  -16.973 38.988  1.00 62.28  ? 269 VAL C CG1 1 
ATOM   10187 C CG2 . VAL C 1 209 ? -71.938  -17.452 36.783  1.00 61.19  ? 269 VAL C CG2 1 
ATOM   10188 N N   . CYS C 1 210 ? -69.399  -19.693 35.302  1.00 52.51  ? 270 CYS C N   1 
ATOM   10189 C CA  . CYS C 1 210 ? -69.536  -20.577 34.108  1.00 55.46  ? 270 CYS C CA  1 
ATOM   10190 C C   . CYS C 1 210 ? -68.397  -21.595 34.079  1.00 49.76  ? 270 CYS C C   1 
ATOM   10191 O O   . CYS C 1 210 ? -67.307  -21.191 34.341  1.00 56.74  ? 270 CYS C O   1 
ATOM   10192 C CB  . CYS C 1 210 ? -69.523  -19.772 32.822  1.00 51.16  ? 270 CYS C CB  1 
ATOM   10193 S SG  . CYS C 1 210 ? -70.828  -18.527 32.795  1.00 67.95  ? 270 CYS C SG  1 
ATOM   10194 N N   . LEU C 1 211 ? -68.679  -22.867 33.812  1.00 47.97  ? 271 LEU C N   1 
ATOM   10195 C CA  . LEU C 1 211 ? -67.695  -23.968 33.932  1.00 49.56  ? 271 LEU C CA  1 
ATOM   10196 C C   . LEU C 1 211 ? -67.807  -24.890 32.718  1.00 50.43  ? 271 LEU C C   1 
ATOM   10197 O O   . LEU C 1 211 ? -68.701  -25.728 32.644  1.00 49.11  ? 271 LEU C O   1 
ATOM   10198 C CB  . LEU C 1 211 ? -67.967  -24.747 35.225  1.00 51.06  ? 271 LEU C CB  1 
ATOM   10199 C CG  . LEU C 1 211 ? -67.243  -26.094 35.345  1.00 51.75  ? 271 LEU C CG  1 
ATOM   10200 C CD1 . LEU C 1 211 ? -65.753  -25.931 35.229  1.00 49.86  ? 271 LEU C CD1 1 
ATOM   10201 C CD2 . LEU C 1 211 ? -67.566  -26.781 36.648  1.00 53.68  ? 271 LEU C CD2 1 
ATOM   10202 N N   . PRO C 1 212 ? -66.897  -24.782 31.725  1.00 44.58  ? 272 PRO C N   1 
ATOM   10203 C CA  . PRO C 1 212 ? -66.949  -25.649 30.559  1.00 41.64  ? 272 PRO C CA  1 
ATOM   10204 C C   . PRO C 1 212 ? -66.398  -27.024 30.925  1.00 42.84  ? 272 PRO C C   1 
ATOM   10205 O O   . PRO C 1 212 ? -65.343  -27.060 31.413  1.00 42.06  ? 272 PRO C O   1 
ATOM   10206 C CB  . PRO C 1 212 ? -66.084  -24.948 29.519  1.00 36.95  ? 272 PRO C CB  1 
ATOM   10207 C CG  . PRO C 1 212 ? -65.501  -23.725 30.189  1.00 35.57  ? 272 PRO C CG  1 
ATOM   10208 C CD  . PRO C 1 212 ? -65.786  -23.832 31.660  1.00 38.60  ? 272 PRO C CD  1 
ATOM   10209 N N   . ILE C 1 213 ? -67.152  -28.093 30.711  1.00 49.83  ? 273 ILE C N   1 
ATOM   10210 C CA  . ILE C 1 213 ? -66.712  -29.480 31.040  1.00 49.22  ? 273 ILE C CA  1 
ATOM   10211 C C   . ILE C 1 213 ? -66.765  -30.349 29.787  1.00 46.75  ? 273 ILE C C   1 
ATOM   10212 O O   . ILE C 1 213 ? -67.671  -30.184 28.975  1.00 52.02  ? 273 ILE C O   1 
ATOM   10213 C CB  . ILE C 1 213 ? -67.584  -30.062 32.160  1.00 54.15  ? 273 ILE C CB  1 
ATOM   10214 C CG1 . ILE C 1 213 ? -67.505  -29.161 33.396  1.00 51.17  ? 273 ILE C CG1 1 
ATOM   10215 C CG2 . ILE C 1 213 ? -67.205  -31.528 32.426  1.00 55.08  ? 273 ILE C CG2 1 
ATOM   10216 C CD1 . ILE C 1 213 ? -68.326  -29.619 34.581  1.00 51.18  ? 273 ILE C CD1 1 
ATOM   10217 N N   . THR C 1 214 ? -65.821  -31.251 29.647  1.00 41.10  ? 274 THR C N   1 
ATOM   10218 C CA  . THR C 1 214 ? -65.870  -32.324 28.630  1.00 46.41  ? 274 THR C CA  1 
ATOM   10219 C C   . THR C 1 214 ? -65.760  -33.661 29.357  1.00 40.49  ? 274 THR C C   1 
ATOM   10220 O O   . THR C 1 214 ? -64.812  -33.808 30.143  1.00 38.46  ? 274 THR C O   1 
ATOM   10221 C CB  . THR C 1 214 ? -64.740  -32.165 27.600  1.00 50.35  ? 274 THR C CB  1 
ATOM   10222 O OG1 . THR C 1 214 ? -64.892  -30.908 26.922  1.00 39.09  ? 274 THR C OG1 1 
ATOM   10223 C CG2 . THR C 1 214 ? -64.697  -33.338 26.632  1.00 52.83  ? 274 THR C CG2 1 
ATOM   10224 N N   . ILE C 1 215 ? -66.648  -34.600 29.073  1.00 40.63  ? 275 ILE C N   1 
ATOM   10225 C CA  . ILE C 1 215 ? -66.515  -35.990 29.586  1.00 47.18  ? 275 ILE C CA  1 
ATOM   10226 C C   . ILE C 1 215 ? -65.837  -36.824 28.516  1.00 47.61  ? 275 ILE C C   1 
ATOM   10227 O O   . ILE C 1 215 ? -66.494  -37.086 27.511  1.00 59.89  ? 275 ILE C O   1 
ATOM   10228 C CB  . ILE C 1 215 ? -67.888  -36.547 29.984  1.00 50.79  ? 275 ILE C CB  1 
ATOM   10229 C CG1 . ILE C 1 215 ? -68.373  -35.805 31.222  1.00 54.94  ? 275 ILE C CG1 1 
ATOM   10230 C CG2 . ILE C 1 215 ? -67.866  -38.045 30.263  1.00 50.93  ? 275 ILE C CG2 1 
ATOM   10231 C CD1 . ILE C 1 215 ? -69.045  -34.538 30.925  1.00 58.39  ? 275 ILE C CD1 1 
ATOM   10232 N N   . ASP C 1 216 ? -64.585  -37.230 28.727  1.00 48.18  ? 276 ASP C N   1 
ATOM   10233 C CA  . ASP C 1 216 ? -63.862  -38.094 27.747  1.00 60.28  ? 276 ASP C CA  1 
ATOM   10234 C C   . ASP C 1 216 ? -64.098  -39.564 28.111  1.00 53.89  ? 276 ASP C C   1 
ATOM   10235 O O   . ASP C 1 216 ? -63.663  -39.991 29.181  1.00 55.73  ? 276 ASP C O   1 
ATOM   10236 C CB  . ASP C 1 216 ? -62.367  -37.756 27.659  1.00 63.99  ? 276 ASP C CB  1 
ATOM   10237 C CG  . ASP C 1 216 ? -61.564  -38.454 26.551  1.00 70.75  ? 276 ASP C CG  1 
ATOM   10238 O OD1 . ASP C 1 216 ? -62.150  -38.966 25.550  1.00 74.26  ? 276 ASP C OD1 1 
ATOM   10239 O OD2 . ASP C 1 216 ? -60.316  -38.467 26.687  1.00 64.25  ? 276 ASP C OD2 1 
ATOM   10240 N N   . VAL C 1 217 ? -64.771  -40.304 27.244  1.00 56.26  ? 277 VAL C N   1 
ATOM   10241 C CA  . VAL C 1 217 ? -65.030  -41.762 27.442  1.00 63.31  ? 277 VAL C CA  1 
ATOM   10242 C C   . VAL C 1 217 ? -64.399  -42.547 26.290  1.00 60.55  ? 277 VAL C C   1 
ATOM   10243 O O   . VAL C 1 217 ? -64.666  -43.750 26.179  1.00 68.51  ? 277 VAL C O   1 
ATOM   10244 C CB  . VAL C 1 217 ? -66.535  -42.048 27.565  1.00 57.13  ? 277 VAL C CB  1 
ATOM   10245 C CG1 . VAL C 1 217 ? -67.066  -41.498 28.861  1.00 60.51  ? 277 VAL C CG1 1 
ATOM   10246 C CG2 . VAL C 1 217 ? -67.313  -41.468 26.400  1.00 60.65  ? 277 VAL C CG2 1 
ATOM   10247 N N   . GLY C 1 218 ? -63.577  -41.876 25.491  1.00 52.92  ? 278 GLY C N   1 
ATOM   10248 C CA  . GLY C 1 218 ? -63.092  -42.398 24.209  1.00 56.45  ? 278 GLY C CA  1 
ATOM   10249 C C   . GLY C 1 218 ? -63.767  -41.726 23.036  1.00 56.59  ? 278 GLY C C   1 
ATOM   10250 O O   . GLY C 1 218 ? -64.552  -40.784 23.248  1.00 74.55  ? 278 GLY C O   1 
ATOM   10251 N N   . THR C 1 219 ? -63.426  -42.179 21.832  1.00 49.80  ? 279 THR C N   1 
ATOM   10252 C CA  . THR C 1 219 ? -63.969  -41.670 20.551  1.00 51.29  ? 279 THR C CA  1 
ATOM   10253 C C   . THR C 1 219 ? -63.907  -42.824 19.560  1.00 46.25  ? 279 THR C C   1 
ATOM   10254 O O   . THR C 1 219 ? -63.038  -43.659 19.758  1.00 41.57  ? 279 THR C O   1 
ATOM   10255 C CB  . THR C 1 219 ? -63.215  -40.407 20.094  1.00 49.56  ? 279 THR C CB  1 
ATOM   10256 O OG1 . THR C 1 219 ? -63.730  -39.931 18.843  1.00 43.80  ? 279 THR C OG1 1 
ATOM   10257 C CG2 . THR C 1 219 ? -61.734  -40.643 19.922  1.00 53.97  ? 279 THR C CG2 1 
ATOM   10258 N N   . ASN C 1 220 ? -64.783  -42.852 18.558  1.00 48.52  ? 280 ASN C N   1 
ATOM   10259 C CA  . ASN C 1 220 ? -64.800  -43.907 17.510  1.00 59.50  ? 280 ASN C CA  1 
ATOM   10260 C C   . ASN C 1 220 ? -64.119  -43.415 16.213  1.00 68.32  ? 280 ASN C C   1 
ATOM   10261 O O   . ASN C 1 220 ? -63.778  -44.265 15.329  1.00 77.80  ? 280 ASN C O   1 
ATOM   10262 C CB  . ASN C 1 220 ? -66.231  -44.362 17.244  1.00 62.49  ? 280 ASN C CB  1 
ATOM   10263 C CG  . ASN C 1 220 ? -66.890  -44.960 18.459  1.00 54.47  ? 280 ASN C CG  1 
ATOM   10264 O OD1 . ASN C 1 220 ? -66.247  -45.583 19.303  1.00 56.24  ? 280 ASN C OD1 1 
ATOM   10265 N ND2 . ASN C 1 220 ? -68.189  -44.776 18.518  1.00 47.92  ? 280 ASN C ND2 1 
ATOM   10266 N N   . ASN C 1 221 ? -63.931  -42.097 16.100  1.00 69.17  ? 281 ASN C N   1 
ATOM   10267 C CA  . ASN C 1 221 ? -63.185  -41.415 15.009  1.00 61.53  ? 281 ASN C CA  1 
ATOM   10268 C C   . ASN C 1 221 ? -61.784  -42.045 14.877  1.00 59.14  ? 281 ASN C C   1 
ATOM   10269 O O   . ASN C 1 221 ? -60.898  -41.721 15.685  1.00 51.76  ? 281 ASN C O   1 
ATOM   10270 C CB  . ASN C 1 221 ? -63.190  -39.912 15.292  1.00 60.65  ? 281 ASN C CB  1 
ATOM   10271 C CG  . ASN C 1 221 ? -62.664  -39.088 14.147  1.00 61.01  ? 281 ASN C CG  1 
ATOM   10272 O OD1 . ASN C 1 221 ? -61.911  -39.608 13.340  1.00 60.80  ? 281 ASN C OD1 1 
ATOM   10273 N ND2 . ASN C 1 221 ? -63.074  -37.824 14.055  1.00 64.92  ? 281 ASN C ND2 1 
ATOM   10274 N N   . GLU C 1 222 ? -61.599  -42.930 13.893  1.00 66.17  ? 282 GLU C N   1 
ATOM   10275 C CA  . GLU C 1 222 ? -60.330  -43.664 13.620  1.00 61.74  ? 282 GLU C CA  1 
ATOM   10276 C C   . GLU C 1 222 ? -59.195  -42.704 13.237  1.00 58.57  ? 282 GLU C C   1 
ATOM   10277 O O   . GLU C 1 222 ? -58.042  -43.013 13.606  1.00 60.57  ? 282 GLU C O   1 
ATOM   10278 C CB  . GLU C 1 222 ? -60.537  -44.663 12.485  1.00 66.26  ? 282 GLU C CB  1 
ATOM   10279 C CG  . GLU C 1 222 ? -61.499  -45.776 12.841  1.00 73.02  ? 282 GLU C CG  1 
ATOM   10280 C CD  . GLU C 1 222 ? -60.928  -46.738 13.858  1.00 73.27  ? 282 GLU C CD  1 
ATOM   10281 O OE1 . GLU C 1 222 ? -59.769  -46.523 14.277  1.00 69.42  ? 282 GLU C OE1 1 
ATOM   10282 O OE2 . GLU C 1 222 ? -61.627  -47.697 14.194  1.00 80.98  ? 282 GLU C OE2 1 
ATOM   10283 N N   . LYS C 1 223 ? -59.497  -41.605 12.527  1.00 50.00  ? 283 LYS C N   1 
ATOM   10284 C CA  . LYS C 1 223 ? -58.510  -40.528 12.210  1.00 55.95  ? 283 LYS C CA  1 
ATOM   10285 C C   . LYS C 1 223 ? -57.927  -39.943 13.517  1.00 58.32  ? 283 LYS C C   1 
ATOM   10286 O O   . LYS C 1 223 ? -56.716  -39.701 13.573  1.00 64.03  ? 283 LYS C O   1 
ATOM   10287 C CB  . LYS C 1 223 ? -59.060  -39.469 11.240  1.00 62.71  ? 283 LYS C CB  1 
ATOM   10288 C CG  . LYS C 1 223 ? -60.149  -38.524 11.749  1.00 85.50  ? 283 LYS C CG  1 
ATOM   10289 C CD  . LYS C 1 223 ? -59.963  -37.014 11.510  1.00 87.87  ? 283 LYS C CD  1 
ATOM   10290 C CE  . LYS C 1 223 ? -61.062  -36.201 12.193  1.00 74.78  ? 283 LYS C CE  1 
ATOM   10291 N NZ  . LYS C 1 223 ? -60.695  -34.773 12.377  1.00 68.25  ? 283 LYS C NZ  1 
ATOM   10292 N N   . LEU C 1 224 ? -58.732  -39.757 14.557  1.00 64.23  ? 284 LEU C N   1 
ATOM   10293 C CA  . LEU C 1 224 ? -58.283  -39.139 15.832  1.00 59.16  ? 284 LEU C CA  1 
ATOM   10294 C C   . LEU C 1 224 ? -57.580  -40.166 16.724  1.00 64.92  ? 284 LEU C C   1 
ATOM   10295 O O   . LEU C 1 224 ? -56.656  -39.751 17.442  1.00 56.86  ? 284 LEU C O   1 
ATOM   10296 C CB  . LEU C 1 224 ? -59.504  -38.551 16.528  1.00 61.89  ? 284 LEU C CB  1 
ATOM   10297 C CG  . LEU C 1 224 ? -60.047  -37.243 15.952  1.00 58.04  ? 284 LEU C CG  1 
ATOM   10298 C CD1 . LEU C 1 224 ? -61.087  -36.674 16.893  1.00 63.57  ? 284 LEU C CD1 1 
ATOM   10299 C CD2 . LEU C 1 224 ? -58.953  -36.207 15.730  1.00 51.21  ? 284 LEU C CD2 1 
ATOM   10300 N N   . LEU C 1 225 ? -57.988  -41.445 16.685  1.00 66.12  ? 285 LEU C N   1 
ATOM   10301 C CA  . LEU C 1 225 ? -57.270  -42.540 17.406  1.00 61.41  ? 285 LEU C CA  1 
ATOM   10302 C C   . LEU C 1 225 ? -55.816  -42.611 16.917  1.00 57.54  ? 285 LEU C C   1 
ATOM   10303 O O   . LEU C 1 225 ? -54.959  -42.863 17.737  1.00 68.01  ? 285 LEU C O   1 
ATOM   10304 C CB  . LEU C 1 225 ? -57.973  -43.889 17.193  1.00 60.53  ? 285 LEU C CB  1 
ATOM   10305 C CG  . LEU C 1 225 ? -59.020  -44.309 18.222  1.00 56.10  ? 285 LEU C CG  1 
ATOM   10306 C CD1 . LEU C 1 225 ? -58.380  -44.685 19.528  1.00 67.19  ? 285 LEU C CD1 1 
ATOM   10307 C CD2 . LEU C 1 225 ? -60.020  -43.214 18.464  1.00 67.51  ? 285 LEU C CD2 1 
ATOM   10308 N N   . ASN C 1 226 ? -55.564  -42.388 15.631  1.00 59.87  ? 286 ASN C N   1 
ATOM   10309 C CA  . ASN C 1 226 ? -54.232  -42.585 15.012  1.00 67.26  ? 286 ASN C CA  1 
ATOM   10310 C C   . ASN C 1 226 ? -53.523  -41.242 14.851  1.00 63.12  ? 286 ASN C C   1 
ATOM   10311 O O   . ASN C 1 226 ? -52.398  -41.255 14.397  1.00 61.09  ? 286 ASN C O   1 
ATOM   10312 C CB  . ASN C 1 226 ? -54.368  -43.356 13.696  1.00 79.63  ? 286 ASN C CB  1 
ATOM   10313 C CG  . ASN C 1 226 ? -54.327  -44.866 13.906  1.00 87.00  ? 286 ASN C CG  1 
ATOM   10314 O OD1 . ASN C 1 226 ? -54.678  -45.425 14.962  1.00 77.29  ? 286 ASN C OD1 1 
ATOM   10315 N ND2 . ASN C 1 226 ? -53.858  -45.555 12.881  1.00 89.98  ? 286 ASN C ND2 1 
ATOM   10316 N N   . ASP C 1 227 ? -54.197  -40.123 15.121  1.00 65.94  ? 287 ASP C N   1 
ATOM   10317 C CA  . ASP C 1 227 ? -53.589  -38.763 15.086  1.00 61.10  ? 287 ASP C CA  1 
ATOM   10318 C C   . ASP C 1 227 ? -52.744  -38.626 16.348  1.00 64.55  ? 287 ASP C C   1 
ATOM   10319 O O   . ASP C 1 227 ? -53.281  -38.917 17.413  1.00 84.41  ? 287 ASP C O   1 
ATOM   10320 C CB  . ASP C 1 227 ? -54.649  -37.658 14.956  1.00 56.56  ? 287 ASP C CB  1 
ATOM   10321 C CG  . ASP C 1 227 ? -54.114  -36.243 14.789  1.00 59.49  ? 287 ASP C CG  1 
ATOM   10322 O OD1 . ASP C 1 227 ? -52.989  -35.952 15.265  1.00 69.03  ? 287 ASP C OD1 1 
ATOM   10323 O OD2 . ASP C 1 227 ? -54.839  -35.427 14.180  1.00 58.53  ? 287 ASP C OD2 1 
ATOM   10324 N N   . GLU C 1 228 ? -51.488  -38.198 16.221  1.00 65.54  ? 288 GLU C N   1 
ATOM   10325 C CA  . GLU C 1 228 ? -50.510  -38.105 17.329  1.00 63.86  ? 288 GLU C CA  1 
ATOM   10326 C C   . GLU C 1 228 ? -50.747  -36.840 18.153  1.00 52.60  ? 288 GLU C C   1 
ATOM   10327 O O   . GLU C 1 228 ? -50.099  -36.743 19.184  1.00 58.89  ? 288 GLU C O   1 
ATOM   10328 C CB  . GLU C 1 228 ? -49.077  -38.134 16.787  1.00 71.50  ? 288 GLU C CB  1 
ATOM   10329 C CG  . GLU C 1 228 ? -48.635  -36.849 16.096  1.00 79.02  ? 288 GLU C CG  1 
ATOM   10330 C CD  . GLU C 1 228 ? -47.238  -36.886 15.467  1.00 86.52  ? 288 GLU C CD  1 
ATOM   10331 O OE1 . GLU C 1 228 ? -46.791  -35.818 14.974  1.00 79.91  ? 288 GLU C OE1 1 
ATOM   10332 O OE2 . GLU C 1 228 ? -46.591  -37.979 15.458  1.00 76.84  ? 288 GLU C OE2 1 
ATOM   10333 N N   . PHE C 1 229 ? -51.610  -35.906 17.738  1.00 50.26  ? 289 PHE C N   1 
ATOM   10334 C CA  . PHE C 1 229 ? -51.939  -34.687 18.544  1.00 56.28  ? 289 PHE C CA  1 
ATOM   10335 C C   . PHE C 1 229 ? -53.294  -34.787 19.249  1.00 54.61  ? 289 PHE C C   1 
ATOM   10336 O O   . PHE C 1 229 ? -53.653  -33.796 19.927  1.00 49.41  ? 289 PHE C O   1 
ATOM   10337 C CB  . PHE C 1 229 ? -51.898  -33.433 17.679  1.00 54.47  ? 289 PHE C CB  1 
ATOM   10338 C CG  . PHE C 1 229 ? -50.506  -33.122 17.206  1.00 63.83  ? 289 PHE C CG  1 
ATOM   10339 C CD1 . PHE C 1 229 ? -49.413  -33.239 18.054  1.00 60.49  ? 289 PHE C CD1 1 
ATOM   10340 C CD2 . PHE C 1 229 ? -50.294  -32.702 15.912  1.00 70.24  ? 289 PHE C CD2 1 
ATOM   10341 C CE1 . PHE C 1 229 ? -48.137  -32.948 17.615  1.00 57.18  ? 289 PHE C CE1 1 
ATOM   10342 C CE2 . PHE C 1 229 ? -49.018  -32.385 15.477  1.00 75.99  ? 289 PHE C CE2 1 
ATOM   10343 C CZ  . PHE C 1 229 ? -47.940  -32.523 16.330  1.00 70.45  ? 289 PHE C CZ  1 
ATOM   10344 N N   . TYR C 1 230 ? -53.986  -35.927 19.131  1.00 51.42  ? 290 TYR C N   1 
ATOM   10345 C CA  . TYR C 1 230 ? -55.284  -36.131 19.806  1.00 55.83  ? 290 TYR C CA  1 
ATOM   10346 C C   . TYR C 1 230 ? -54.981  -36.071 21.300  1.00 59.33  ? 290 TYR C C   1 
ATOM   10347 O O   . TYR C 1 230 ? -54.041  -36.726 21.742  1.00 65.90  ? 290 TYR C O   1 
ATOM   10348 C CB  . TYR C 1 230 ? -56.027  -37.400 19.365  1.00 55.94  ? 290 TYR C CB  1 
ATOM   10349 C CG  . TYR C 1 230 ? -57.346  -37.666 20.072  1.00 56.88  ? 290 TYR C CG  1 
ATOM   10350 C CD1 . TYR C 1 230 ? -58.426  -36.785 20.013  1.00 53.13  ? 290 TYR C CD1 1 
ATOM   10351 C CD2 . TYR C 1 230 ? -57.510  -38.830 20.815  1.00 57.59  ? 290 TYR C CD2 1 
ATOM   10352 C CE1 . TYR C 1 230 ? -59.616  -37.068 20.688  1.00 56.33  ? 290 TYR C CE1 1 
ATOM   10353 C CE2 . TYR C 1 230 ? -58.683  -39.121 21.492  1.00 54.89  ? 290 TYR C CE2 1 
ATOM   10354 C CZ  . TYR C 1 230 ? -59.746  -38.237 21.437  1.00 56.85  ? 290 TYR C CZ  1 
ATOM   10355 O OH  . TYR C 1 230 ? -60.876  -38.574 22.148  1.00 60.24  ? 290 TYR C OH  1 
ATOM   10356 N N   . ILE C 1 231 ? -55.758  -35.262 22.016  1.00 55.67  ? 291 ILE C N   1 
ATOM   10357 C CA  . ILE C 1 231 ? -55.574  -34.903 23.444  1.00 51.20  ? 291 ILE C CA  1 
ATOM   10358 C C   . ILE C 1 231 ? -56.441  -35.817 24.301  1.00 44.67  ? 291 ILE C C   1 
ATOM   10359 O O   . ILE C 1 231 ? -56.414  -35.641 25.514  1.00 62.28  ? 291 ILE C O   1 
ATOM   10360 C CB  . ILE C 1 231 ? -55.930  -33.416 23.687  1.00 57.99  ? 291 ILE C CB  1 
ATOM   10361 C CG1 . ILE C 1 231 ? -57.421  -33.148 23.448  1.00 61.70  ? 291 ILE C CG1 1 
ATOM   10362 C CG2 . ILE C 1 231 ? -55.058  -32.500 22.853  1.00 56.45  ? 291 ILE C CG2 1 
ATOM   10363 C CD1 . ILE C 1 231 ? -57.886  -31.768 23.840  1.00 62.09  ? 291 ILE C CD1 1 
ATOM   10364 N N   . GLY C 1 232 ? -57.233  -36.714 23.733  1.00 41.86  ? 292 GLY C N   1 
ATOM   10365 C CA  . GLY C 1 232 ? -58.081  -37.636 24.533  1.00 45.57  ? 292 GLY C CA  1 
ATOM   10366 C C   . GLY C 1 232 ? -57.479  -39.029 24.752  1.00 38.22  ? 292 GLY C C   1 
ATOM   10367 O O   . GLY C 1 232 ? -56.400  -39.287 24.292  1.00 39.17  ? 292 GLY C O   1 
ATOM   10368 N N   . LEU C 1 233 ? -58.212  -39.899 25.418  1.00 41.42  ? 293 LEU C N   1 
ATOM   10369 C CA  . LEU C 1 233 ? -57.869  -41.334 25.620  1.00 43.29  ? 293 LEU C CA  1 
ATOM   10370 C C   . LEU C 1 233 ? -57.891  -42.011 24.263  1.00 43.32  ? 293 LEU C C   1 
ATOM   10371 O O   . LEU C 1 233 ? -58.935  -41.895 23.597  1.00 57.12  ? 293 LEU C O   1 
ATOM   10372 C CB  . LEU C 1 233 ? -58.904  -42.008 26.535  1.00 45.13  ? 293 LEU C CB  1 
ATOM   10373 C CG  . LEU C 1 233 ? -59.231  -41.286 27.849  1.00 45.54  ? 293 LEU C CG  1 
ATOM   10374 C CD1 . LEU C 1 233 ? -60.426  -41.946 28.471  1.00 55.77  ? 293 LEU C CD1 1 
ATOM   10375 C CD2 . LEU C 1 233 ? -58.069  -41.226 28.839  1.00 41.50  ? 293 LEU C CD2 1 
ATOM   10376 N N   . ARG C 1 234 ? -56.799  -42.679 23.885  1.00 47.40  ? 294 ARG C N   1 
ATOM   10377 C CA  . ARG C 1 234 ? -56.723  -43.515 22.644  1.00 53.40  ? 294 ARG C CA  1 
ATOM   10378 C C   . ARG C 1 234 ? -57.474  -44.831 22.857  1.00 50.09  ? 294 ARG C C   1 
ATOM   10379 O O   . ARG C 1 234 ? -56.817  -45.875 22.904  1.00 56.72  ? 294 ARG C O   1 
ATOM   10380 C CB  . ARG C 1 234 ? -55.277  -43.811 22.220  1.00 54.22  ? 294 ARG C CB  1 
ATOM   10381 C CG  . ARG C 1 234 ? -54.649  -42.664 21.447  1.00 56.13  ? 294 ARG C CG  1 
ATOM   10382 C CD  . ARG C 1 234 ? -53.145  -42.678 21.287  1.00 60.24  ? 294 ARG C CD  1 
ATOM   10383 N NE  . ARG C 1 234 ? -52.684  -41.314 21.099  1.00 62.51  ? 294 ARG C NE  1 
ATOM   10384 C CZ  . ARG C 1 234 ? -52.978  -40.575 20.041  1.00 64.90  ? 294 ARG C CZ  1 
ATOM   10385 N NH1 . ARG C 1 234 ? -53.724  -41.077 19.078  1.00 65.96  ? 294 ARG C NH1 1 
ATOM   10386 N NH2 . ARG C 1 234 ? -52.510  -39.340 19.897  1.00 70.50  ? 294 ARG C NH2 1 
ATOM   10387 N N   . GLN C 1 235 ? -58.800  -44.771 22.939  1.00 45.91  ? 295 GLN C N   1 
ATOM   10388 C CA  . GLN C 1 235 ? -59.685  -45.960 22.999  1.00 53.78  ? 295 GLN C CA  1 
ATOM   10389 C C   . GLN C 1 235 ? -61.042  -45.610 22.388  1.00 60.66  ? 295 GLN C C   1 
ATOM   10390 O O   . GLN C 1 235 ? -61.368  -44.400 22.350  1.00 66.16  ? 295 GLN C O   1 
ATOM   10391 C CB  . GLN C 1 235 ? -59.853  -46.422 24.442  1.00 63.04  ? 295 GLN C CB  1 
ATOM   10392 C CG  . GLN C 1 235 ? -60.341  -45.317 25.373  1.00 65.30  ? 295 GLN C CG  1 
ATOM   10393 C CD  . GLN C 1 235 ? -60.782  -45.835 26.712  1.00 60.63  ? 295 GLN C CD  1 
ATOM   10394 O OE1 . GLN C 1 235 ? -60.050  -45.705 27.693  1.00 60.45  ? 295 GLN C OE1 1 
ATOM   10395 N NE2 . GLN C 1 235 ? -61.986  -46.393 26.745  1.00 55.28  ? 295 GLN C NE2 1 
ATOM   10396 N N   . LYS C 1 236 ? -61.801  -46.614 21.929  1.00 66.83  ? 296 LYS C N   1 
ATOM   10397 C CA  . LYS C 1 236 ? -63.147  -46.375 21.337  1.00 65.21  ? 296 LYS C CA  1 
ATOM   10398 C C   . LYS C 1 236 ? -64.106  -46.133 22.513  1.00 64.38  ? 296 LYS C C   1 
ATOM   10399 O O   . LYS C 1 236 ? -63.736  -46.468 23.642  1.00 67.70  ? 296 LYS C O   1 
ATOM   10400 C CB  . LYS C 1 236 ? -63.516  -47.448 20.313  1.00 63.62  ? 296 LYS C CB  1 
ATOM   10401 C CG  . LYS C 1 236 ? -63.344  -48.879 20.770  1.00 81.18  ? 296 LYS C CG  1 
ATOM   10402 C CD  . LYS C 1 236 ? -61.996  -49.455 20.351  1.00 86.31  ? 296 LYS C CD  1 
ATOM   10403 C CE  . LYS C 1 236 ? -61.575  -50.675 21.142  1.00 84.20  ? 296 LYS C CE  1 
ATOM   10404 N NZ  . LYS C 1 236 ? -60.104  -50.709 21.327  1.00 79.25  ? 296 LYS C NZ  1 
ATOM   10405 N N   . ARG C 1 237 ? -65.252  -45.497 22.277  1.00 64.47  ? 297 ARG C N   1 
ATOM   10406 C CA  . ARG C 1 237 ? -66.170  -45.054 23.360  1.00 68.56  ? 297 ARG C CA  1 
ATOM   10407 C C   . ARG C 1 237 ? -66.601  -46.242 24.229  1.00 69.51  ? 297 ARG C C   1 
ATOM   10408 O O   . ARG C 1 237 ? -66.958  -47.312 23.677  1.00 79.41  ? 297 ARG C O   1 
ATOM   10409 C CB  . ARG C 1 237 ? -67.413  -44.365 22.791  1.00 68.02  ? 297 ARG C CB  1 
ATOM   10410 C CG  . ARG C 1 237 ? -67.169  -42.918 22.397  1.00 63.36  ? 297 ARG C CG  1 
ATOM   10411 C CD  . ARG C 1 237 ? -68.421  -42.192 21.972  1.00 63.92  ? 297 ARG C CD  1 
ATOM   10412 N NE  . ARG C 1 237 ? -67.961  -40.889 21.547  1.00 69.05  ? 297 ARG C NE  1 
ATOM   10413 C CZ  . ARG C 1 237 ? -67.825  -39.837 22.345  1.00 69.78  ? 297 ARG C CZ  1 
ATOM   10414 N NH1 . ARG C 1 237 ? -68.146  -39.910 23.628  1.00 70.84  ? 297 ARG C NH1 1 
ATOM   10415 N NH2 . ARG C 1 237 ? -67.375  -38.705 21.841  1.00 69.60  ? 297 ARG C NH2 1 
ATOM   10416 N N   . ALA C 1 238 ? -66.585  -46.037 25.540  1.00 68.91  ? 298 ALA C N   1 
ATOM   10417 C CA  . ALA C 1 238 ? -67.235  -46.910 26.541  1.00 76.11  ? 298 ALA C CA  1 
ATOM   10418 C C   . ALA C 1 238 ? -68.759  -46.894 26.349  1.00 77.92  ? 298 ALA C C   1 
ATOM   10419 O O   . ALA C 1 238 ? -69.330  -45.775 26.133  1.00 69.17  ? 298 ALA C O   1 
ATOM   10420 C CB  . ALA C 1 238 ? -66.855  -46.433 27.921  1.00 81.63  ? 298 ALA C CB  1 
ATOM   10421 N N   . THR C 1 239 ? -69.388  -48.070 26.491  1.00 71.32  ? 299 THR C N   1 
ATOM   10422 C CA  . THR C 1 239 ? -70.861  -48.280 26.402  1.00 70.39  ? 299 THR C CA  1 
ATOM   10423 C C   . THR C 1 239 ? -71.420  -48.850 27.717  1.00 68.06  ? 299 THR C C   1 
ATOM   10424 O O   . THR C 1 239 ? -70.642  -49.220 28.593  1.00 70.15  ? 299 THR C O   1 
ATOM   10425 C CB  . THR C 1 239 ? -71.171  -49.165 25.185  1.00 70.67  ? 299 THR C CB  1 
ATOM   10426 O OG1 . THR C 1 239 ? -70.690  -50.491 25.429  1.00 75.57  ? 299 THR C OG1 1 
ATOM   10427 C CG2 . THR C 1 239 ? -70.561  -48.596 23.925  1.00 65.53  ? 299 THR C CG2 1 
ATOM   10428 N N   . GLY C 1 240 ? -72.748  -48.947 27.838  1.00 72.52  ? 300 GLY C N   1 
ATOM   10429 C CA  . GLY C 1 240 ? -73.446  -49.609 28.960  1.00 74.15  ? 300 GLY C CA  1 
ATOM   10430 C C   . GLY C 1 240 ? -72.980  -49.107 30.327  1.00 71.09  ? 300 GLY C C   1 
ATOM   10431 O O   . GLY C 1 240 ? -72.799  -47.873 30.512  1.00 78.10  ? 300 GLY C O   1 
ATOM   10432 N N   . GLU C 1 241 ? -72.769  -50.034 31.255  1.00 79.35  ? 301 GLU C N   1 
ATOM   10433 C CA  . GLU C 1 241 ? -72.542  -49.691 32.687  1.00 85.14  ? 301 GLU C CA  1 
ATOM   10434 C C   . GLU C 1 241 ? -71.303  -48.795 32.778  1.00 77.22  ? 301 GLU C C   1 
ATOM   10435 O O   . GLU C 1 241 ? -71.407  -47.855 33.544  1.00 75.29  ? 301 GLU C O   1 
ATOM   10436 C CB  . GLU C 1 241 ? -72.528  -50.912 33.617  1.00 92.88  ? 301 GLU C CB  1 
ATOM   10437 C CG  . GLU C 1 241 ? -71.923  -50.595 34.992  1.00 115.47 ? 301 GLU C CG  1 
ATOM   10438 C CD  . GLU C 1 241 ? -72.697  -51.002 36.247  1.00 126.45 ? 301 GLU C CD  1 
ATOM   10439 O OE1 . GLU C 1 241 ? -72.600  -52.186 36.646  1.00 139.69 ? 301 GLU C OE1 1 
ATOM   10440 O OE2 . GLU C 1 241 ? -73.360  -50.115 36.860  1.00 113.14 ? 301 GLU C OE2 1 
ATOM   10441 N N   . GLU C 1 242 ? -70.220  -49.024 32.019  1.00 75.40  ? 302 GLU C N   1 
ATOM   10442 C CA  . GLU C 1 242 ? -68.964  -48.236 32.141  1.00 76.98  ? 302 GLU C CA  1 
ATOM   10443 C C   . GLU C 1 242 ? -69.252  -46.753 31.836  1.00 66.68  ? 302 GLU C C   1 
ATOM   10444 O O   . GLU C 1 242 ? -68.846  -45.889 32.639  1.00 78.58  ? 302 GLU C O   1 
ATOM   10445 C CB  . GLU C 1 242 ? -67.868  -48.812 31.241  1.00 73.64  ? 302 GLU C CB  1 
ATOM   10446 C CG  . GLU C 1 242 ? -66.479  -48.384 31.668  1.00 80.53  ? 302 GLU C CG  1 
ATOM   10447 C CD  . GLU C 1 242 ? -65.356  -48.606 30.674  1.00 89.31  ? 302 GLU C CD  1 
ATOM   10448 O OE1 . GLU C 1 242 ? -65.546  -49.400 29.718  1.00 96.24  ? 302 GLU C OE1 1 
ATOM   10449 O OE2 . GLU C 1 242 ? -64.285  -47.977 30.863  1.00 88.37  ? 302 GLU C OE2 1 
ATOM   10450 N N   . TYR C 1 243 ? -69.942  -46.458 30.744  1.00 56.54  ? 303 TYR C N   1 
ATOM   10451 C CA  . TYR C 1 243 ? -70.411  -45.092 30.403  1.00 61.13  ? 303 TYR C CA  1 
ATOM   10452 C C   . TYR C 1 243 ? -71.251  -44.567 31.572  1.00 65.20  ? 303 TYR C C   1 
ATOM   10453 O O   . TYR C 1 243 ? -70.903  -43.560 32.211  1.00 75.19  ? 303 TYR C O   1 
ATOM   10454 C CB  . TYR C 1 243 ? -71.216  -45.078 29.094  1.00 62.39  ? 303 TYR C CB  1 
ATOM   10455 C CG  . TYR C 1 243 ? -71.696  -43.701 28.686  1.00 68.39  ? 303 TYR C CG  1 
ATOM   10456 C CD1 . TYR C 1 243 ? -70.853  -42.805 28.037  1.00 70.13  ? 303 TYR C CD1 1 
ATOM   10457 C CD2 . TYR C 1 243 ? -72.980  -43.270 28.971  1.00 61.15  ? 303 TYR C CD2 1 
ATOM   10458 C CE1 . TYR C 1 243 ? -71.265  -41.532 27.682  1.00 62.55  ? 303 TYR C CE1 1 
ATOM   10459 C CE2 . TYR C 1 243 ? -73.412  -42.005 28.594  1.00 63.27  ? 303 TYR C CE2 1 
ATOM   10460 C CZ  . TYR C 1 243 ? -72.553  -41.125 27.950  1.00 64.74  ? 303 TYR C CZ  1 
ATOM   10461 O OH  . TYR C 1 243 ? -72.943  -39.857 27.586  1.00 72.63  ? 303 TYR C OH  1 
ATOM   10462 N N   . ASP C 1 244 ? -72.329  -45.292 31.866  1.00 67.40  ? 304 ASP C N   1 
ATOM   10463 C CA  . ASP C 1 244 ? -73.414  -44.860 32.786  1.00 60.99  ? 304 ASP C CA  1 
ATOM   10464 C C   . ASP C 1 244 ? -72.811  -44.478 34.130  1.00 56.60  ? 304 ASP C C   1 
ATOM   10465 O O   . ASP C 1 244 ? -73.190  -43.415 34.622  1.00 65.21  ? 304 ASP C O   1 
ATOM   10466 C CB  . ASP C 1 244 ? -74.461  -45.960 32.977  1.00 64.39  ? 304 ASP C CB  1 
ATOM   10467 C CG  . ASP C 1 244 ? -75.368  -46.197 31.782  1.00 65.14  ? 304 ASP C CG  1 
ATOM   10468 O OD1 . ASP C 1 244 ? -75.641  -45.232 31.036  1.00 65.55  ? 304 ASP C OD1 1 
ATOM   10469 O OD2 . ASP C 1 244 ? -75.805  -47.348 31.626  1.00 72.73  ? 304 ASP C OD2 1 
ATOM   10470 N N   . GLU C 1 245 ? -71.914  -45.302 34.686  1.00 62.56  ? 305 GLU C N   1 
ATOM   10471 C CA  . GLU C 1 245 ? -71.333  -45.111 36.050  1.00 62.67  ? 305 GLU C CA  1 
ATOM   10472 C C   . GLU C 1 245 ? -70.630  -43.763 36.136  1.00 50.09  ? 305 GLU C C   1 
ATOM   10473 O O   . GLU C 1 245 ? -70.812  -43.072 37.133  1.00 44.40  ? 305 GLU C O   1 
ATOM   10474 C CB  . GLU C 1 245 ? -70.285  -46.170 36.362  1.00 74.24  ? 305 GLU C CB  1 
ATOM   10475 C CG  . GLU C 1 245 ? -70.832  -47.428 36.976  1.00 77.59  ? 305 GLU C CG  1 
ATOM   10476 C CD  . GLU C 1 245 ? -69.778  -48.527 36.990  1.00 89.24  ? 305 GLU C CD  1 
ATOM   10477 O OE1 . GLU C 1 245 ? -68.576  -48.286 36.614  1.00 86.61  ? 305 GLU C OE1 1 
ATOM   10478 O OE2 . GLU C 1 245 ? -70.148  -49.630 37.385  1.00 91.61  ? 305 GLU C OE2 1 
ATOM   10479 N N   . LEU C 1 246 ? -69.831  -43.446 35.125  1.00 48.82  ? 306 LEU C N   1 
ATOM   10480 C CA  . LEU C 1 246 ? -69.109  -42.168 35.064  1.00 55.19  ? 306 LEU C CA  1 
ATOM   10481 C C   . LEU C 1 246 ? -70.140  -41.041 35.101  1.00 50.05  ? 306 LEU C C   1 
ATOM   10482 O O   . LEU C 1 246 ? -69.997  -40.109 35.916  1.00 47.09  ? 306 LEU C O   1 
ATOM   10483 C CB  . LEU C 1 246 ? -68.244  -42.104 33.803  1.00 62.72  ? 306 LEU C CB  1 
ATOM   10484 C CG  . LEU C 1 246 ? -67.241  -40.951 33.806  1.00 69.82  ? 306 LEU C CG  1 
ATOM   10485 C CD1 . LEU C 1 246 ? -66.196  -41.179 34.899  1.00 70.79  ? 306 LEU C CD1 1 
ATOM   10486 C CD2 . LEU C 1 246 ? -66.593  -40.781 32.448  1.00 65.67  ? 306 LEU C CD2 1 
ATOM   10487 N N   . ILE C 1 247 ? -71.174  -41.147 34.279  1.00 54.81  ? 307 ILE C N   1 
ATOM   10488 C CA  . ILE C 1 247 ? -72.187  -40.064 34.158  1.00 65.71  ? 307 ILE C CA  1 
ATOM   10489 C C   . ILE C 1 247 ? -72.856  -39.871 35.521  1.00 70.97  ? 307 ILE C C   1 
ATOM   10490 O O   . ILE C 1 247 ? -72.936  -38.726 35.980  1.00 90.00  ? 307 ILE C O   1 
ATOM   10491 C CB  . ILE C 1 247 ? -73.205  -40.348 33.049  1.00 63.18  ? 307 ILE C CB  1 
ATOM   10492 C CG1 . ILE C 1 247 ? -72.528  -40.521 31.690  1.00 73.60  ? 307 ILE C CG1 1 
ATOM   10493 C CG2 . ILE C 1 247 ? -74.231  -39.235 33.018  1.00 66.15  ? 307 ILE C CG2 1 
ATOM   10494 C CD1 . ILE C 1 247 ? -71.987  -39.234 31.085  1.00 82.12  ? 307 ILE C CD1 1 
ATOM   10495 N N   . GLU C 1 248 ? -73.323  -40.943 36.152  1.00 71.56  ? 308 GLU C N   1 
ATOM   10496 C CA  . GLU C 1 248 ? -74.190  -40.824 37.350  1.00 82.99  ? 308 GLU C CA  1 
ATOM   10497 C C   . GLU C 1 248 ? -73.288  -40.404 38.522  1.00 83.68  ? 308 GLU C C   1 
ATOM   10498 O O   . GLU C 1 248 ? -73.792  -39.780 39.470  1.00 89.89  ? 308 GLU C O   1 
ATOM   10499 C CB  . GLU C 1 248 ? -75.057  -42.082 37.532  1.00 85.65  ? 308 GLU C CB  1 
ATOM   10500 C CG  . GLU C 1 248 ? -74.376  -43.279 38.186  1.00 95.68  ? 308 GLU C CG  1 
ATOM   10501 C CD  . GLU C 1 248 ? -75.253  -44.528 38.187  1.00 105.44 ? 308 GLU C CD  1 
ATOM   10502 O OE1 . GLU C 1 248 ? -76.221  -44.526 38.967  1.00 105.14 ? 308 GLU C OE1 1 
ATOM   10503 O OE2 . GLU C 1 248 ? -74.991  -45.489 37.401  1.00 89.33  ? 308 GLU C OE2 1 
ATOM   10504 N N   . GLU C 1 249 ? -71.985  -40.661 38.429  1.00 75.79  ? 309 GLU C N   1 
ATOM   10505 C CA  . GLU C 1 249 ? -70.999  -40.198 39.434  1.00 66.64  ? 309 GLU C CA  1 
ATOM   10506 C C   . GLU C 1 249 ? -70.742  -38.705 39.191  1.00 67.30  ? 309 GLU C C   1 
ATOM   10507 O O   . GLU C 1 249 ? -70.643  -37.937 40.193  1.00 60.86  ? 309 GLU C O   1 
ATOM   10508 C CB  . GLU C 1 249 ? -69.733  -41.046 39.359  1.00 59.02  ? 309 GLU C CB  1 
ATOM   10509 C CG  . GLU C 1 249 ? -68.585  -40.439 40.116  1.00 63.52  ? 309 GLU C CG  1 
ATOM   10510 C CD  . GLU C 1 249 ? -67.235  -41.129 40.001  1.00 68.21  ? 309 GLU C CD  1 
ATOM   10511 O OE1 . GLU C 1 249 ? -67.117  -42.176 39.337  1.00 74.25  ? 309 GLU C OE1 1 
ATOM   10512 O OE2 . GLU C 1 249 ? -66.294  -40.598 40.616  1.00 79.31  ? 309 GLU C OE2 1 
ATOM   10513 N N   . PHE C 1 250 ? -70.636  -38.311 37.913  1.00 61.51  ? 310 PHE C N   1 
ATOM   10514 C CA  . PHE C 1 250 ? -70.517  -36.892 37.487  1.00 58.12  ? 310 PHE C CA  1 
ATOM   10515 C C   . PHE C 1 250 ? -71.726  -36.126 38.055  1.00 60.65  ? 310 PHE C C   1 
ATOM   10516 O O   . PHE C 1 250 ? -71.554  -35.120 38.765  1.00 67.62  ? 310 PHE C O   1 
ATOM   10517 C CB  . PHE C 1 250 ? -70.381  -36.761 35.964  1.00 49.89  ? 310 PHE C CB  1 
ATOM   10518 C CG  . PHE C 1 250 ? -70.448  -35.326 35.496  1.00 53.42  ? 310 PHE C CG  1 
ATOM   10519 C CD1 . PHE C 1 250 ? -69.386  -34.460 35.707  1.00 54.44  ? 310 PHE C CD1 1 
ATOM   10520 C CD2 . PHE C 1 250 ? -71.587  -34.805 34.897  1.00 54.44  ? 310 PHE C CD2 1 
ATOM   10521 C CE1 . PHE C 1 250 ? -69.444  -33.133 35.300  1.00 47.21  ? 310 PHE C CE1 1 
ATOM   10522 C CE2 . PHE C 1 250 ? -71.653  -33.468 34.516  1.00 50.22  ? 310 PHE C CE2 1 
ATOM   10523 C CZ  . PHE C 1 250 ? -70.585  -32.628 34.729  1.00 47.61  ? 310 PHE C CZ  1 
ATOM   10524 N N   . MET C 1 251 ? -72.922  -36.649 37.798  1.00 72.52  ? 311 MET C N   1 
ATOM   10525 C CA  . MET C 1 251 ? -74.235  -36.017 38.140  1.00 70.85  ? 311 MET C CA  1 
ATOM   10526 C C   . MET C 1 251 ? -74.373  -35.962 39.674  1.00 66.08  ? 311 MET C C   1 
ATOM   10527 O O   . MET C 1 251 ? -74.812  -34.924 40.193  1.00 63.18  ? 311 MET C O   1 
ATOM   10528 C CB  . MET C 1 251 ? -75.415  -36.780 37.491  1.00 63.71  ? 311 MET C CB  1 
ATOM   10529 C CG  . MET C 1 251 ? -75.587  -36.534 35.974  1.00 59.71  ? 311 MET C CG  1 
ATOM   10530 S SD  . MET C 1 251 ? -76.419  -34.961 35.532  1.00 68.86  ? 311 MET C SD  1 
ATOM   10531 C CE  . MET C 1 251 ? -75.044  -33.826 35.506  1.00 71.80  ? 311 MET C CE  1 
ATOM   10532 N N   . SER C 1 252 ? -73.965  -37.023 40.377  1.00 64.16  ? 312 SER C N   1 
ATOM   10533 C CA  . SER C 1 252 ? -73.812  -37.023 41.853  1.00 67.93  ? 312 SER C CA  1 
ATOM   10534 C C   . SER C 1 252 ? -72.949  -35.828 42.261  1.00 70.45  ? 312 SER C C   1 
ATOM   10535 O O   . SER C 1 252 ? -73.456  -34.922 42.976  1.00 63.25  ? 312 SER C O   1 
ATOM   10536 C CB  . SER C 1 252 ? -73.180  -38.297 42.359  1.00 73.02  ? 312 SER C CB  1 
ATOM   10537 O OG  . SER C 1 252 ? -74.148  -39.209 42.848  1.00 87.12  ? 312 SER C OG  1 
ATOM   10538 N N   . ALA C 1 253 ? -71.701  -35.833 41.779  1.00 63.69  ? 313 ALA C N   1 
ATOM   10539 C CA  . ALA C 1 253 ? -70.599  -34.965 42.237  1.00 57.38  ? 313 ALA C CA  1 
ATOM   10540 C C   . ALA C 1 253 ? -70.944  -33.490 42.017  1.00 57.91  ? 313 ALA C C   1 
ATOM   10541 O O   . ALA C 1 253 ? -70.588  -32.641 42.868  1.00 48.70  ? 313 ALA C O   1 
ATOM   10542 C CB  . ALA C 1 253 ? -69.357  -35.348 41.488  1.00 61.93  ? 313 ALA C CB  1 
ATOM   10543 N N   . VAL C 1 254 ? -71.591  -33.198 40.894  1.00 60.81  ? 314 VAL C N   1 
ATOM   10544 C CA  . VAL C 1 254 ? -71.950  -31.807 40.511  1.00 64.54  ? 314 VAL C CA  1 
ATOM   10545 C C   . VAL C 1 254 ? -72.927  -31.303 41.567  1.00 56.94  ? 314 VAL C C   1 
ATOM   10546 O O   . VAL C 1 254 ? -72.769  -30.156 42.014  1.00 40.82  ? 314 VAL C O   1 
ATOM   10547 C CB  . VAL C 1 254 ? -72.559  -31.782 39.100  1.00 72.63  ? 314 VAL C CB  1 
ATOM   10548 C CG1 . VAL C 1 254 ? -73.145  -30.428 38.740  1.00 83.98  ? 314 VAL C CG1 1 
ATOM   10549 C CG2 . VAL C 1 254 ? -71.531  -32.197 38.067  1.00 76.57  ? 314 VAL C CG2 1 
ATOM   10550 N N   . LYS C 1 255 ? -73.875  -32.172 41.941  1.00 63.40  ? 315 LYS C N   1 
ATOM   10551 C CA  . LYS C 1 255 ? -75.013  -31.828 42.834  1.00 75.25  ? 315 LYS C CA  1 
ATOM   10552 C C   . LYS C 1 255 ? -74.459  -31.503 44.223  1.00 71.47  ? 315 LYS C C   1 
ATOM   10553 O O   . LYS C 1 255 ? -74.888  -30.467 44.773  1.00 67.95  ? 315 LYS C O   1 
ATOM   10554 C CB  . LYS C 1 255 ? -76.076  -32.929 42.907  1.00 80.72  ? 315 LYS C CB  1 
ATOM   10555 C CG  . LYS C 1 255 ? -77.500  -32.422 43.123  1.00 78.70  ? 315 LYS C CG  1 
ATOM   10556 C CD  . LYS C 1 255 ? -78.295  -33.259 44.113  1.00 79.76  ? 315 LYS C CD  1 
ATOM   10557 C CE  . LYS C 1 255 ? -79.746  -33.496 43.747  1.00 78.61  ? 315 LYS C CE  1 
ATOM   10558 N NZ  . LYS C 1 255 ? -80.135  -34.887 44.094  1.00 77.34  ? 315 LYS C NZ  1 
ATOM   10559 N N   . GLN C 1 256 ? -73.553  -32.355 44.739  1.00 66.15  ? 316 GLN C N   1 
ATOM   10560 C CA  . GLN C 1 256 ? -72.952  -32.240 46.099  1.00 55.33  ? 316 GLN C CA  1 
ATOM   10561 C C   . GLN C 1 256 ? -72.140  -30.948 46.132  1.00 51.74  ? 316 GLN C C   1 
ATOM   10562 O O   . GLN C 1 256 ? -72.281  -30.203 47.094  1.00 56.46  ? 316 GLN C O   1 
ATOM   10563 C CB  . GLN C 1 256 ? -72.070  -33.434 46.482  1.00 56.32  ? 316 GLN C CB  1 
ATOM   10564 C CG  . GLN C 1 256 ? -72.771  -34.780 46.386  1.00 66.77  ? 316 GLN C CG  1 
ATOM   10565 C CD  . GLN C 1 256 ? -71.846  -35.908 46.763  1.00 68.70  ? 316 GLN C CD  1 
ATOM   10566 O OE1 . GLN C 1 256 ? -71.015  -35.752 47.653  1.00 70.61  ? 316 GLN C OE1 1 
ATOM   10567 N NE2 . GLN C 1 256 ? -71.987  -37.040 46.084  1.00 66.87  ? 316 GLN C NE2 1 
ATOM   10568 N N   . PHE C 1 257 ? -71.364  -30.663 45.090  1.00 50.99  ? 317 PHE C N   1 
ATOM   10569 C CA  . PHE C 1 257 ? -70.427  -29.517 45.078  1.00 56.50  ? 317 PHE C CA  1 
ATOM   10570 C C   . PHE C 1 257 ? -71.196  -28.201 44.852  1.00 51.22  ? 317 PHE C C   1 
ATOM   10571 O O   . PHE C 1 257 ? -71.021  -27.264 45.654  1.00 54.87  ? 317 PHE C O   1 
ATOM   10572 C CB  . PHE C 1 257 ? -69.282  -29.814 44.102  1.00 61.55  ? 317 PHE C CB  1 
ATOM   10573 C CG  . PHE C 1 257 ? -67.940  -29.289 44.550  1.00 64.72  ? 317 PHE C CG  1 
ATOM   10574 C CD1 . PHE C 1 257 ? -67.406  -29.616 45.783  1.00 74.51  ? 317 PHE C CD1 1 
ATOM   10575 C CD2 . PHE C 1 257 ? -67.258  -28.384 43.774  1.00 70.11  ? 317 PHE C CD2 1 
ATOM   10576 C CE1 . PHE C 1 257 ? -66.216  -29.057 46.215  1.00 71.42  ? 317 PHE C CE1 1 
ATOM   10577 C CE2 . PHE C 1 257 ? -66.066  -27.823 44.197  1.00 80.37  ? 317 PHE C CE2 1 
ATOM   10578 C CZ  . PHE C 1 257 ? -65.536  -28.179 45.414  1.00 76.68  ? 317 PHE C CZ  1 
ATOM   10579 N N   . TYR C 1 258 ? -72.044  -28.127 43.830  1.00 47.13  ? 318 TYR C N   1 
ATOM   10580 C CA  . TYR C 1 258 ? -72.584  -26.842 43.315  1.00 50.35  ? 318 TYR C CA  1 
ATOM   10581 C C   . TYR C 1 258 ? -74.049  -26.648 43.749  1.00 52.01  ? 318 TYR C C   1 
ATOM   10582 O O   . TYR C 1 258 ? -74.580  -25.491 43.639  1.00 46.48  ? 318 TYR C O   1 
ATOM   10583 C CB  . TYR C 1 258 ? -72.357  -26.778 41.800  1.00 50.01  ? 318 TYR C CB  1 
ATOM   10584 C CG  . TYR C 1 258 ? -70.907  -26.878 41.375  1.00 51.71  ? 318 TYR C CG  1 
ATOM   10585 C CD1 . TYR C 1 258 ? -69.947  -25.981 41.824  1.00 47.14  ? 318 TYR C CD1 1 
ATOM   10586 C CD2 . TYR C 1 258 ? -70.495  -27.862 40.490  1.00 53.87  ? 318 TYR C CD2 1 
ATOM   10587 C CE1 . TYR C 1 258 ? -68.626  -26.056 41.400  1.00 52.53  ? 318 TYR C CE1 1 
ATOM   10588 C CE2 . TYR C 1 258 ? -69.176  -27.953 40.065  1.00 52.55  ? 318 TYR C CE2 1 
ATOM   10589 C CZ  . TYR C 1 258 ? -68.230  -27.056 40.526  1.00 50.46  ? 318 TYR C CZ  1 
ATOM   10590 O OH  . TYR C 1 258 ? -66.918  -27.157 40.151  1.00 47.39  ? 318 TYR C OH  1 
ATOM   10591 N N   . GLY C 1 259 ? -74.679  -27.716 44.249  1.00 49.51  ? 319 GLY C N   1 
ATOM   10592 C CA  . GLY C 1 259 ? -76.081  -27.695 44.684  1.00 54.58  ? 319 GLY C CA  1 
ATOM   10593 C C   . GLY C 1 259 ? -77.003  -28.116 43.556  1.00 68.20  ? 319 GLY C C   1 
ATOM   10594 O O   . GLY C 1 259 ? -76.530  -28.644 42.529  1.00 64.51  ? 319 GLY C O   1 
ATOM   10595 N N   . GLU C 1 260 ? -78.303  -27.908 43.744  1.00 81.58  ? 320 GLU C N   1 
ATOM   10596 C CA  . GLU C 1 260 ? -79.341  -28.341 42.773  1.00 78.51  ? 320 GLU C CA  1 
ATOM   10597 C C   . GLU C 1 260 ? -79.684  -27.166 41.845  1.00 66.23  ? 320 GLU C C   1 
ATOM   10598 O O   . GLU C 1 260 ? -79.867  -27.460 40.657  1.00 79.98  ? 320 GLU C O   1 
ATOM   10599 C CB  . GLU C 1 260 ? -80.517  -28.973 43.519  1.00 86.33  ? 320 GLU C CB  1 
ATOM   10600 C CG  . GLU C 1 260 ? -81.901  -28.469 43.104  1.00 93.42  ? 320 GLU C CG  1 
ATOM   10601 C CD  . GLU C 1 260 ? -82.442  -29.033 41.808  1.00 88.56  ? 320 GLU C CD  1 
ATOM   10602 O OE1 . GLU C 1 260 ? -81.779  -29.881 41.192  1.00 95.02  ? 320 GLU C OE1 1 
ATOM   10603 O OE2 . GLU C 1 260 ? -83.549  -28.647 41.430  1.00 107.71 ? 320 GLU C OE2 1 
ATOM   10604 N N   . LYS C 1 261 ? -79.653  -25.910 42.311  1.00 51.96  ? 321 LYS C N   1 
ATOM   10605 C CA  . LYS C 1 261 ? -79.874  -24.708 41.454  1.00 63.05  ? 321 LYS C CA  1 
ATOM   10606 C C   . LYS C 1 261 ? -78.782  -24.509 40.369  1.00 59.54  ? 321 LYS C C   1 
ATOM   10607 O O   . LYS C 1 261 ? -78.870  -23.526 39.594  1.00 64.05  ? 321 LYS C O   1 
ATOM   10608 C CB  . LYS C 1 261 ? -79.981  -23.462 42.342  1.00 66.00  ? 321 LYS C CB  1 
ATOM   10609 C CG  . LYS C 1 261 ? -81.140  -23.433 43.318  1.00 69.54  ? 321 LYS C CG  1 
ATOM   10610 C CD  . LYS C 1 261 ? -80.769  -22.665 44.554  1.00 74.84  ? 321 LYS C CD  1 
ATOM   10611 C CE  . LYS C 1 261 ? -81.971  -22.290 45.372  1.00 82.89  ? 321 LYS C CE  1 
ATOM   10612 N NZ  . LYS C 1 261 ? -81.980  -20.828 45.594  1.00 90.04  ? 321 LYS C NZ  1 
ATOM   10613 N N   . VAL C 1 262 ? -77.792  -25.391 40.235  1.00 56.30  ? 322 VAL C N   1 
ATOM   10614 C CA  . VAL C 1 262 ? -76.805  -25.277 39.120  1.00 54.92  ? 322 VAL C CA  1 
ATOM   10615 C C   . VAL C 1 262 ? -77.420  -25.817 37.819  1.00 66.05  ? 322 VAL C C   1 
ATOM   10616 O O   . VAL C 1 262 ? -77.849  -27.018 37.774  1.00 71.23  ? 322 VAL C O   1 
ATOM   10617 C CB  . VAL C 1 262 ? -75.472  -25.975 39.430  1.00 52.23  ? 322 VAL C CB  1 
ATOM   10618 C CG1 . VAL C 1 262 ? -75.583  -27.496 39.435  1.00 47.41  ? 322 VAL C CG1 1 
ATOM   10619 C CG2 . VAL C 1 262 ? -74.389  -25.501 38.466  1.00 53.75  ? 322 VAL C CG2 1 
ATOM   10620 N N   . LEU C 1 263 ? -77.434  -24.954 36.796  1.00 66.03  ? 323 LEU C N   1 
ATOM   10621 C CA  . LEU C 1 263 ? -77.871  -25.269 35.419  1.00 58.09  ? 323 LEU C CA  1 
ATOM   10622 C C   . LEU C 1 263 ? -76.813  -26.170 34.784  1.00 62.56  ? 323 LEU C C   1 
ATOM   10623 O O   . LEU C 1 263 ? -75.655  -25.785 34.798  1.00 73.50  ? 323 LEU C O   1 
ATOM   10624 C CB  . LEU C 1 263 ? -78.027  -23.964 34.640  1.00 49.91  ? 323 LEU C CB  1 
ATOM   10625 C CG  . LEU C 1 263 ? -78.474  -24.120 33.192  1.00 55.56  ? 323 LEU C CG  1 
ATOM   10626 C CD1 . LEU C 1 263 ? -79.539  -25.230 33.033  1.00 50.07  ? 323 LEU C CD1 1 
ATOM   10627 C CD2 . LEU C 1 263 ? -78.953  -22.762 32.659  1.00 56.72  ? 323 LEU C CD2 1 
ATOM   10628 N N   . ILE C 1 264 ? -77.210  -27.350 34.313  1.00 61.34  ? 324 ILE C N   1 
ATOM   10629 C CA  . ILE C 1 264 ? -76.354  -28.296 33.554  1.00 59.87  ? 324 ILE C CA  1 
ATOM   10630 C C   . ILE C 1 264 ? -76.886  -28.315 32.120  1.00 63.83  ? 324 ILE C C   1 
ATOM   10631 O O   . ILE C 1 264 ? -77.901  -28.984 31.891  1.00 80.35  ? 324 ILE C O   1 
ATOM   10632 C CB  . ILE C 1 264 ? -76.361  -29.689 34.225  1.00 63.40  ? 324 ILE C CB  1 
ATOM   10633 C CG1 . ILE C 1 264 ? -75.860  -29.614 35.675  1.00 60.22  ? 324 ILE C CG1 1 
ATOM   10634 C CG2 . ILE C 1 264 ? -75.579  -30.709 33.406  1.00 56.45  ? 324 ILE C CG2 1 
ATOM   10635 C CD1 . ILE C 1 264 ? -76.222  -30.812 36.516  1.00 62.86  ? 324 ILE C CD1 1 
ATOM   10636 N N   . GLN C 1 265 ? -76.224  -27.596 31.202  1.00 60.82  ? 325 GLN C N   1 
ATOM   10637 C CA  . GLN C 1 265 ? -76.559  -27.532 29.746  1.00 54.02  ? 325 GLN C CA  1 
ATOM   10638 C C   . GLN C 1 265 ? -75.768  -28.607 28.999  1.00 49.20  ? 325 GLN C C   1 
ATOM   10639 O O   . GLN C 1 265 ? -74.560  -28.462 28.878  1.00 46.58  ? 325 GLN C O   1 
ATOM   10640 C CB  . GLN C 1 265 ? -76.286  -26.135 29.194  1.00 52.96  ? 325 GLN C CB  1 
ATOM   10641 C CG  . GLN C 1 265 ? -76.573  -25.986 27.710  1.00 49.86  ? 325 GLN C CG  1 
ATOM   10642 C CD  . GLN C 1 265 ? -76.687  -24.513 27.407  1.00 55.59  ? 325 GLN C CD  1 
ATOM   10643 O OE1 . GLN C 1 265 ? -77.268  -23.763 28.185  1.00 54.70  ? 325 GLN C OE1 1 
ATOM   10644 N NE2 . GLN C 1 265 ? -76.123  -24.069 26.291  1.00 57.43  ? 325 GLN C NE2 1 
ATOM   10645 N N   . PHE C 1 266 ? -76.438  -29.687 28.610  1.00 49.84  ? 326 PHE C N   1 
ATOM   10646 C CA  . PHE C 1 266 ? -75.887  -30.763 27.760  1.00 53.00  ? 326 PHE C CA  1 
ATOM   10647 C C   . PHE C 1 266 ? -75.775  -30.254 26.319  1.00 56.26  ? 326 PHE C C   1 
ATOM   10648 O O   . PHE C 1 266 ? -76.742  -29.590 25.829  1.00 56.17  ? 326 PHE C O   1 
ATOM   10649 C CB  . PHE C 1 266 ? -76.765  -32.009 27.796  1.00 59.63  ? 326 PHE C CB  1 
ATOM   10650 C CG  . PHE C 1 266 ? -76.905  -32.625 29.153  1.00 65.73  ? 326 PHE C CG  1 
ATOM   10651 C CD1 . PHE C 1 266 ? -75.813  -33.160 29.820  1.00 69.04  ? 326 PHE C CD1 1 
ATOM   10652 C CD2 . PHE C 1 266 ? -78.149  -32.690 29.747  1.00 75.16  ? 326 PHE C CD2 1 
ATOM   10653 C CE1 . PHE C 1 266 ? -75.960  -33.697 31.088  1.00 68.06  ? 326 PHE C CE1 1 
ATOM   10654 C CE2 . PHE C 1 266 ? -78.299  -33.298 30.988  1.00 81.00  ? 326 PHE C CE2 1 
ATOM   10655 C CZ  . PHE C 1 266 ? -77.202  -33.780 31.667  1.00 68.16  ? 326 PHE C CZ  1 
ATOM   10656 N N   . GLU C 1 267 ? -74.644  -30.567 25.657  1.00 56.49  ? 327 GLU C N   1 
ATOM   10657 C CA  . GLU C 1 267 ? -74.339  -30.168 24.258  1.00 55.32  ? 327 GLU C CA  1 
ATOM   10658 C C   . GLU C 1 267 ? -73.826  -31.388 23.496  1.00 51.93  ? 327 GLU C C   1 
ATOM   10659 O O   . GLU C 1 267 ? -72.945  -32.102 24.020  1.00 54.41  ? 327 GLU C O   1 
ATOM   10660 C CB  . GLU C 1 267 ? -73.277  -29.071 24.234  1.00 62.43  ? 327 GLU C CB  1 
ATOM   10661 C CG  . GLU C 1 267 ? -73.750  -27.704 24.693  1.00 60.47  ? 327 GLU C CG  1 
ATOM   10662 C CD  . GLU C 1 267 ? -74.655  -26.998 23.709  1.00 63.95  ? 327 GLU C CD  1 
ATOM   10663 O OE1 . GLU C 1 267 ? -74.916  -27.539 22.578  1.00 58.51  ? 327 GLU C OE1 1 
ATOM   10664 O OE2 . GLU C 1 267 ? -75.098  -25.904 24.083  1.00 84.41  ? 327 GLU C OE2 1 
ATOM   10665 N N   . ASP C 1 268 ? -74.389  -31.630 22.319  1.00 52.35  ? 328 ASP C N   1 
ATOM   10666 C CA  . ASP C 1 268 ? -73.768  -32.489 21.279  1.00 62.07  ? 328 ASP C CA  1 
ATOM   10667 C C   . ASP C 1 268 ? -73.535  -33.907 21.810  1.00 62.51  ? 328 ASP C C   1 
ATOM   10668 O O   . ASP C 1 268 ? -72.451  -34.436 21.574  1.00 63.75  ? 328 ASP C O   1 
ATOM   10669 C CB  . ASP C 1 268 ? -72.489  -31.819 20.769  1.00 65.89  ? 328 ASP C CB  1 
ATOM   10670 C CG  . ASP C 1 268 ? -72.710  -30.446 20.143  1.00 77.99  ? 328 ASP C CG  1 
ATOM   10671 O OD1 . ASP C 1 268 ? -73.864  -30.014 19.989  1.00 101.99 ? 328 ASP C OD1 1 
ATOM   10672 O OD2 . ASP C 1 268 ? -71.731  -29.818 19.805  1.00 72.78  ? 328 ASP C OD2 1 
ATOM   10673 N N   . PHE C 1 269 ? -74.530  -34.511 22.461  1.00 58.55  ? 329 PHE C N   1 
ATOM   10674 C CA  . PHE C 1 269 ? -74.587  -35.975 22.693  1.00 55.66  ? 329 PHE C CA  1 
ATOM   10675 C C   . PHE C 1 269 ? -75.364  -36.610 21.534  1.00 53.32  ? 329 PHE C C   1 
ATOM   10676 O O   . PHE C 1 269 ? -76.052  -35.851 20.852  1.00 55.87  ? 329 PHE C O   1 
ATOM   10677 C CB  . PHE C 1 269 ? -75.280  -36.259 24.026  1.00 64.69  ? 329 PHE C CB  1 
ATOM   10678 C CG  . PHE C 1 269 ? -74.511  -35.883 25.271  1.00 67.79  ? 329 PHE C CG  1 
ATOM   10679 C CD1 . PHE C 1 269 ? -74.410  -34.546 25.656  1.00 63.50  ? 329 PHE C CD1 1 
ATOM   10680 C CD2 . PHE C 1 269 ? -73.943  -36.867 26.086  1.00 60.46  ? 329 PHE C CD2 1 
ATOM   10681 C CE1 . PHE C 1 269 ? -73.722  -34.194 26.805  1.00 58.99  ? 329 PHE C CE1 1 
ATOM   10682 C CE2 . PHE C 1 269 ? -73.246  -36.512 27.232  1.00 56.11  ? 329 PHE C CE2 1 
ATOM   10683 C CZ  . PHE C 1 269 ? -73.144  -35.176 27.588  1.00 63.37  ? 329 PHE C CZ  1 
ATOM   10684 N N   . ALA C 1 270 ? -75.294  -37.936 21.365  1.00 54.05  ? 330 ALA C N   1 
ATOM   10685 C CA  . ALA C 1 270 ? -76.115  -38.745 20.428  1.00 63.69  ? 330 ALA C CA  1 
ATOM   10686 C C   . ALA C 1 270 ? -77.560  -38.781 20.926  1.00 71.44  ? 330 ALA C C   1 
ATOM   10687 O O   . ALA C 1 270 ? -77.753  -38.481 22.109  1.00 92.61  ? 330 ALA C O   1 
ATOM   10688 C CB  . ALA C 1 270 ? -75.572  -40.153 20.333  1.00 67.03  ? 330 ALA C CB  1 
ATOM   10689 N N   . ASN C 1 271 ? -78.515  -39.216 20.087  1.00 84.68  ? 331 ASN C N   1 
ATOM   10690 C CA  . ASN C 1 271 ? -79.925  -39.460 20.494  1.00 90.48  ? 331 ASN C CA  1 
ATOM   10691 C C   . ASN C 1 271 ? -79.965  -40.267 21.796  1.00 90.27  ? 331 ASN C C   1 
ATOM   10692 O O   . ASN C 1 271 ? -80.341  -39.648 22.821  1.00 73.84  ? 331 ASN C O   1 
ATOM   10693 C CB  . ASN C 1 271 ? -80.736  -40.142 19.388  1.00 98.31  ? 331 ASN C CB  1 
ATOM   10694 C CG  . ASN C 1 271 ? -80.891  -39.273 18.157  1.00 96.34  ? 331 ASN C CG  1 
ATOM   10695 O OD1 . ASN C 1 271 ? -80.370  -38.165 18.066  1.00 92.33  ? 331 ASN C OD1 1 
ATOM   10696 N ND2 . ASN C 1 271 ? -81.619  -39.775 17.175  1.00 116.07 ? 331 ASN C ND2 1 
ATOM   10697 N N   . HIS C 1 272 ? -79.571  -41.556 21.787  1.00 82.18  ? 332 HIS C N   1 
ATOM   10698 C CA  . HIS C 1 272 ? -79.808  -42.450 22.949  1.00 83.09  ? 332 HIS C CA  1 
ATOM   10699 C C   . HIS C 1 272 ? -79.507  -41.668 24.228  1.00 74.31  ? 332 HIS C C   1 
ATOM   10700 O O   . HIS C 1 272 ? -80.420  -41.530 25.057  1.00 77.87  ? 332 HIS C O   1 
ATOM   10701 C CB  . HIS C 1 272 ? -79.032  -43.774 22.852  1.00 94.74  ? 332 HIS C CB  1 
ATOM   10702 C CG  . HIS C 1 272 ? -79.326  -44.741 23.962  1.00 106.78 ? 332 HIS C CG  1 
ATOM   10703 N ND1 . HIS C 1 272 ? -80.616  -45.205 24.270  1.00 107.28 ? 332 HIS C ND1 1 
ATOM   10704 C CD2 . HIS C 1 272 ? -78.505  -45.302 24.875  1.00 114.51 ? 332 HIS C CD2 1 
ATOM   10705 C CE1 . HIS C 1 272 ? -80.560  -46.006 25.310  1.00 115.39 ? 332 HIS C CE1 1 
ATOM   10706 N NE2 . HIS C 1 272 ? -79.273  -46.101 25.689  1.00 129.08 ? 332 HIS C NE2 1 
ATOM   10707 N N   . ASN C 1 273 ? -78.294  -41.120 24.347  1.00 67.97  ? 333 ASN C N   1 
ATOM   10708 C CA  . ASN C 1 273 ? -77.822  -40.475 25.598  1.00 76.74  ? 333 ASN C CA  1 
ATOM   10709 C C   . ASN C 1 273 ? -78.595  -39.179 25.851  1.00 77.19  ? 333 ASN C C   1 
ATOM   10710 O O   . ASN C 1 273 ? -79.128  -39.066 26.955  1.00 84.42  ? 333 ASN C O   1 
ATOM   10711 C CB  . ASN C 1 273 ? -76.308  -40.272 25.613  1.00 84.14  ? 333 ASN C CB  1 
ATOM   10712 C CG  . ASN C 1 273 ? -75.571  -41.588 25.481  1.00 84.28  ? 333 ASN C CG  1 
ATOM   10713 O OD1 . ASN C 1 273 ? -74.769  -41.752 24.567  1.00 108.68 ? 333 ASN C OD1 1 
ATOM   10714 N ND2 . ASN C 1 273 ? -75.849  -42.539 26.361  1.00 65.20  ? 333 ASN C ND2 1 
ATOM   10715 N N   . ALA C 1 274 ? -78.689  -38.248 24.892  1.00 70.43  ? 334 ALA C N   1 
ATOM   10716 C CA  . ALA C 1 274 ? -79.241  -36.881 25.102  1.00 70.61  ? 334 ALA C CA  1 
ATOM   10717 C C   . ALA C 1 274 ? -80.622  -36.949 25.754  1.00 73.53  ? 334 ALA C C   1 
ATOM   10718 O O   . ALA C 1 274 ? -80.953  -36.001 26.509  1.00 80.00  ? 334 ALA C O   1 
ATOM   10719 C CB  . ALA C 1 274 ? -79.298  -36.116 23.812  1.00 69.33  ? 334 ALA C CB  1 
ATOM   10720 N N   . PHE C 1 275 ? -81.380  -38.012 25.433  1.00 82.92  ? 335 PHE C N   1 
ATOM   10721 C CA  . PHE C 1 275 ? -82.751  -38.313 25.935  1.00 81.84  ? 335 PHE C CA  1 
ATOM   10722 C C   . PHE C 1 275 ? -82.664  -38.985 27.320  1.00 81.71  ? 335 PHE C C   1 
ATOM   10723 O O   . PHE C 1 275 ? -83.286  -38.441 28.233  1.00 84.04  ? 335 PHE C O   1 
ATOM   10724 C CB  . PHE C 1 275 ? -83.575  -39.107 24.906  1.00 83.36  ? 335 PHE C CB  1 
ATOM   10725 C CG  . PHE C 1 275 ? -84.076  -38.308 23.715  1.00 80.54  ? 335 PHE C CG  1 
ATOM   10726 C CD1 . PHE C 1 275 ? -84.752  -37.096 23.872  1.00 72.71  ? 335 PHE C CD1 1 
ATOM   10727 C CD2 . PHE C 1 275 ? -83.873  -38.773 22.419  1.00 82.93  ? 335 PHE C CD2 1 
ATOM   10728 C CE1 . PHE C 1 275 ? -85.189  -36.362 22.774  1.00 70.80  ? 335 PHE C CE1 1 
ATOM   10729 C CE2 . PHE C 1 275 ? -84.352  -38.059 21.320  1.00 79.75  ? 335 PHE C CE2 1 
ATOM   10730 C CZ  . PHE C 1 275 ? -84.997  -36.848 21.498  1.00 73.71  ? 335 PHE C CZ  1 
ATOM   10731 N N   . ASP C 1 276 ? -81.907  -40.071 27.523  1.00 81.88  ? 336 ASP C N   1 
ATOM   10732 C CA  . ASP C 1 276 ? -81.775  -40.719 28.863  1.00 77.80  ? 336 ASP C CA  1 
ATOM   10733 C C   . ASP C 1 276 ? -81.336  -39.704 29.914  1.00 72.11  ? 336 ASP C C   1 
ATOM   10734 O O   . ASP C 1 276 ? -81.752  -39.886 31.064  1.00 86.35  ? 336 ASP C O   1 
ATOM   10735 C CB  . ASP C 1 276 ? -80.797  -41.893 28.885  1.00 76.67  ? 336 ASP C CB  1 
ATOM   10736 C CG  . ASP C 1 276 ? -81.191  -42.954 27.884  1.00 88.31  ? 336 ASP C CG  1 
ATOM   10737 O OD1 . ASP C 1 276 ? -81.917  -42.609 26.919  1.00 104.27 ? 336 ASP C OD1 1 
ATOM   10738 O OD2 . ASP C 1 276 ? -80.777  -44.101 28.069  1.00 101.99 ? 336 ASP C OD2 1 
ATOM   10739 N N   . LEU C 1 277 ? -80.533  -38.701 29.540  1.00 69.67  ? 337 LEU C N   1 
ATOM   10740 C CA  . LEU C 1 277 ? -80.006  -37.662 30.474  1.00 70.04  ? 337 LEU C CA  1 
ATOM   10741 C C   . LEU C 1 277 ? -81.158  -36.739 30.880  1.00 61.73  ? 337 LEU C C   1 
ATOM   10742 O O   . LEU C 1 277 ? -81.215  -36.350 32.048  1.00 70.22  ? 337 LEU C O   1 
ATOM   10743 C CB  . LEU C 1 277 ? -78.877  -36.845 29.813  1.00 78.32  ? 337 LEU C CB  1 
ATOM   10744 C CG  . LEU C 1 277 ? -77.425  -37.260 30.076  1.00 81.27  ? 337 LEU C CG  1 
ATOM   10745 C CD1 . LEU C 1 277 ? -77.215  -38.774 29.972  1.00 73.68  ? 337 LEU C CD1 1 
ATOM   10746 C CD2 . LEU C 1 277 ? -76.536  -36.508 29.100  1.00 89.30  ? 337 LEU C CD2 1 
ATOM   10747 N N   . LEU C 1 278 ? -82.021  -36.370 29.936  1.00 59.73  ? 338 LEU C N   1 
ATOM   10748 C CA  . LEU C 1 278 ? -83.192  -35.503 30.230  1.00 62.70  ? 338 LEU C CA  1 
ATOM   10749 C C   . LEU C 1 278 ? -84.263  -36.325 30.970  1.00 63.81  ? 338 LEU C C   1 
ATOM   10750 O O   . LEU C 1 278 ? -84.962  -35.747 31.797  1.00 52.39  ? 338 LEU C O   1 
ATOM   10751 C CB  . LEU C 1 278 ? -83.698  -34.873 28.929  1.00 63.07  ? 338 LEU C CB  1 
ATOM   10752 C CG  . LEU C 1 278 ? -83.172  -33.456 28.644  1.00 66.53  ? 338 LEU C CG  1 
ATOM   10753 C CD1 . LEU C 1 278 ? -83.662  -32.949 27.303  1.00 70.53  ? 338 LEU C CD1 1 
ATOM   10754 C CD2 . LEU C 1 278 ? -83.615  -32.461 29.701  1.00 71.37  ? 338 LEU C CD2 1 
ATOM   10755 N N   . GLU C 1 279 ? -84.374  -37.629 30.697  1.00 73.45  ? 339 GLU C N   1 
ATOM   10756 C CA  . GLU C 1 279 ? -85.306  -38.578 31.367  1.00 67.26  ? 339 GLU C CA  1 
ATOM   10757 C C   . GLU C 1 279 ? -84.880  -38.753 32.824  1.00 68.89  ? 339 GLU C C   1 
ATOM   10758 O O   . GLU C 1 279 ? -85.629  -38.269 33.715  1.00 89.59  ? 339 GLU C O   1 
ATOM   10759 C CB  . GLU C 1 279 ? -85.322  -39.922 30.651  1.00 81.06  ? 339 GLU C CB  1 
ATOM   10760 C CG  . GLU C 1 279 ? -86.415  -40.846 31.141  1.00 96.71  ? 339 GLU C CG  1 
ATOM   10761 C CD  . GLU C 1 279 ? -86.310  -42.237 30.562  1.00 105.79 ? 339 GLU C CD  1 
ATOM   10762 O OE1 . GLU C 1 279 ? -87.152  -42.568 29.704  1.00 116.38 ? 339 GLU C OE1 1 
ATOM   10763 O OE2 . GLU C 1 279 ? -85.378  -42.970 30.961  1.00 115.45 ? 339 GLU C OE2 1 
ATOM   10764 N N   . LYS C 1 280 ? -83.713  -39.359 33.062  1.00 69.22  ? 340 LYS C N   1 
ATOM   10765 C CA  . LYS C 1 280 ? -83.198  -39.703 34.419  1.00 79.22  ? 340 LYS C CA  1 
ATOM   10766 C C   . LYS C 1 280 ? -83.025  -38.461 35.319  1.00 75.03  ? 340 LYS C C   1 
ATOM   10767 O O   . LYS C 1 280 ? -83.384  -38.549 36.502  1.00 74.40  ? 340 LYS C O   1 
ATOM   10768 C CB  . LYS C 1 280 ? -81.898  -40.505 34.299  1.00 77.36  ? 340 LYS C CB  1 
ATOM   10769 C CG  . LYS C 1 280 ? -81.225  -40.849 35.626  1.00 92.43  ? 340 LYS C CG  1 
ATOM   10770 C CD  . LYS C 1 280 ? -80.546  -42.211 35.736  1.00 100.43 ? 340 LYS C CD  1 
ATOM   10771 C CE  . LYS C 1 280 ? -79.393  -42.440 34.777  1.00 109.82 ? 340 LYS C CE  1 
ATOM   10772 N NZ  . LYS C 1 280 ? -79.040  -43.875 34.655  1.00 106.43 ? 340 LYS C NZ  1 
ATOM   10773 N N   . TYR C 1 281 ? -82.500  -37.344 34.812  1.00 73.61  ? 341 TYR C N   1 
ATOM   10774 C CA  . TYR C 1 281 ? -81.998  -36.236 35.677  1.00 74.30  ? 341 TYR C CA  1 
ATOM   10775 C C   . TYR C 1 281 ? -82.915  -35.008 35.604  1.00 81.43  ? 341 TYR C C   1 
ATOM   10776 O O   . TYR C 1 281 ? -82.509  -33.968 36.182  1.00 102.74 ? 341 TYR C O   1 
ATOM   10777 C CB  . TYR C 1 281 ? -80.525  -35.933 35.369  1.00 71.16  ? 341 TYR C CB  1 
ATOM   10778 C CG  . TYR C 1 281 ? -79.606  -37.121 35.584  1.00 69.31  ? 341 TYR C CG  1 
ATOM   10779 C CD1 . TYR C 1 281 ? -79.226  -37.519 36.856  1.00 62.58  ? 341 TYR C CD1 1 
ATOM   10780 C CD2 . TYR C 1 281 ? -79.155  -37.885 34.525  1.00 69.38  ? 341 TYR C CD2 1 
ATOM   10781 C CE1 . TYR C 1 281 ? -78.413  -38.619 37.058  1.00 59.54  ? 341 TYR C CE1 1 
ATOM   10782 C CE2 . TYR C 1 281 ? -78.336  -38.986 34.714  1.00 62.74  ? 341 TYR C CE2 1 
ATOM   10783 C CZ  . TYR C 1 281 ? -77.954  -39.348 35.983  1.00 59.39  ? 341 TYR C CZ  1 
ATOM   10784 O OH  . TYR C 1 281 ? -77.157  -40.436 36.150  1.00 61.95  ? 341 TYR C OH  1 
ATOM   10785 N N   . SER C 1 282 ? -84.131  -35.125 35.047  1.00 79.20  ? 342 SER C N   1 
ATOM   10786 C CA  . SER C 1 282 ? -85.149  -34.030 35.091  1.00 74.16  ? 342 SER C CA  1 
ATOM   10787 C C   . SER C 1 282 ? -85.639  -33.827 36.521  1.00 73.30  ? 342 SER C C   1 
ATOM   10788 O O   . SER C 1 282 ? -85.915  -32.686 36.911  1.00 77.33  ? 342 SER C O   1 
ATOM   10789 C CB  . SER C 1 282 ? -86.307  -34.296 34.188  1.00 76.90  ? 342 SER C CB  1 
ATOM   10790 O OG  . SER C 1 282 ? -85.907  -34.192 32.832  1.00 86.27  ? 342 SER C OG  1 
ATOM   10791 N N   . LYS C 1 283 ? -85.728  -34.916 37.276  1.00 80.90  ? 343 LYS C N   1 
ATOM   10792 C CA  . LYS C 1 283 ? -86.261  -34.951 38.655  1.00 82.70  ? 343 LYS C CA  1 
ATOM   10793 C C   . LYS C 1 283 ? -85.194  -34.376 39.603  1.00 80.48  ? 343 LYS C C   1 
ATOM   10794 O O   . LYS C 1 283 ? -85.448  -33.351 40.258  1.00 91.58  ? 343 LYS C O   1 
ATOM   10795 C CB  . LYS C 1 283 ? -86.625  -36.405 39.000  1.00 104.84 ? 343 LYS C CB  1 
ATOM   10796 C CG  . LYS C 1 283 ? -87.048  -37.323 37.840  1.00 121.05 ? 343 LYS C CG  1 
ATOM   10797 C CD  . LYS C 1 283 ? -88.499  -37.153 37.377  1.00 131.71 ? 343 LYS C CD  1 
ATOM   10798 C CE  . LYS C 1 283 ? -88.864  -37.946 36.135  1.00 124.31 ? 343 LYS C CE  1 
ATOM   10799 N NZ  . LYS C 1 283 ? -88.320  -37.328 34.903  1.00 113.50 ? 343 LYS C NZ  1 
ATOM   10800 N N   . SER C 1 284 ? -84.018  -35.000 39.637  1.00 72.17  ? 344 SER C N   1 
ATOM   10801 C CA  . SER C 1 284 ? -82.938  -34.705 40.615  1.00 67.00  ? 344 SER C CA  1 
ATOM   10802 C C   . SER C 1 284 ? -82.269  -33.350 40.327  1.00 61.12  ? 344 SER C C   1 
ATOM   10803 O O   . SER C 1 284 ? -81.826  -32.720 41.317  1.00 60.11  ? 344 SER C O   1 
ATOM   10804 C CB  . SER C 1 284 ? -81.947  -35.845 40.676  1.00 72.00  ? 344 SER C CB  1 
ATOM   10805 O OG  . SER C 1 284 ? -81.812  -36.457 39.404  1.00 79.56  ? 344 SER C OG  1 
ATOM   10806 N N   . HIS C 1 285 ? -82.190  -32.905 39.059  1.00 56.85  ? 345 HIS C N   1 
ATOM   10807 C CA  . HIS C 1 285 ? -81.315  -31.772 38.630  1.00 57.64  ? 345 HIS C CA  1 
ATOM   10808 C C   . HIS C 1 285 ? -82.066  -30.736 37.788  1.00 52.99  ? 345 HIS C C   1 
ATOM   10809 O O   . HIS C 1 285 ? -83.168  -30.991 37.349  1.00 61.68  ? 345 HIS C O   1 
ATOM   10810 C CB  . HIS C 1 285 ? -80.075  -32.283 37.878  1.00 64.96  ? 345 HIS C CB  1 
ATOM   10811 C CG  . HIS C 1 285 ? -79.182  -33.208 38.649  1.00 71.06  ? 345 HIS C CG  1 
ATOM   10812 N ND1 . HIS C 1 285 ? -79.524  -34.537 38.905  1.00 72.77  ? 345 HIS C ND1 1 
ATOM   10813 C CD2 . HIS C 1 285 ? -77.964  -33.023 39.204  1.00 73.37  ? 345 HIS C CD2 1 
ATOM   10814 C CE1 . HIS C 1 285 ? -78.559  -35.115 39.598  1.00 73.70  ? 345 HIS C CE1 1 
ATOM   10815 N NE2 . HIS C 1 285 ? -77.590  -34.213 39.788  1.00 73.79  ? 345 HIS C NE2 1 
ATOM   10816 N N   . LEU C 1 286 ? -81.466  -29.569 37.597  1.00 57.26  ? 346 LEU C N   1 
ATOM   10817 C CA  . LEU C 1 286 ? -81.935  -28.536 36.624  1.00 54.72  ? 346 LEU C CA  1 
ATOM   10818 C C   . LEU C 1 286 ? -81.131  -28.730 35.323  1.00 57.75  ? 346 LEU C C   1 
ATOM   10819 O O   . LEU C 1 286 ? -80.076  -28.104 35.137  1.00 52.83  ? 346 LEU C O   1 
ATOM   10820 C CB  . LEU C 1 286 ? -81.713  -27.161 37.260  1.00 50.96  ? 346 LEU C CB  1 
ATOM   10821 C CG  . LEU C 1 286 ? -81.913  -25.926 36.398  1.00 54.91  ? 346 LEU C CG  1 
ATOM   10822 C CD1 . LEU C 1 286 ? -83.370  -25.724 36.085  1.00 65.61  ? 346 LEU C CD1 1 
ATOM   10823 C CD2 . LEU C 1 286 ? -81.393  -24.687 37.099  1.00 59.33  ? 346 LEU C CD2 1 
ATOM   10824 N N   . VAL C 1 287 ? -81.563  -29.673 34.487  1.00 63.01  ? 347 VAL C N   1 
ATOM   10825 C CA  . VAL C 1 287 ? -80.874  -30.087 33.225  1.00 56.71  ? 347 VAL C CA  1 
ATOM   10826 C C   . VAL C 1 287 ? -81.634  -29.476 32.034  1.00 55.67  ? 347 VAL C C   1 
ATOM   10827 O O   . VAL C 1 287 ? -82.864  -29.313 32.098  1.00 53.52  ? 347 VAL C O   1 
ATOM   10828 C CB  . VAL C 1 287 ? -80.741  -31.625 33.110  1.00 57.48  ? 347 VAL C CB  1 
ATOM   10829 C CG1 . VAL C 1 287 ? -80.047  -32.220 34.322  1.00 58.16  ? 347 VAL C CG1 1 
ATOM   10830 C CG2 . VAL C 1 287 ? -82.054  -32.341 32.884  1.00 57.48  ? 347 VAL C CG2 1 
ATOM   10831 N N   . PHE C 1 288 ? -80.916  -29.145 30.966  1.00 60.33  ? 348 PHE C N   1 
ATOM   10832 C CA  . PHE C 1 288 ? -81.427  -28.456 29.751  1.00 59.52  ? 348 PHE C CA  1 
ATOM   10833 C C   . PHE C 1 288 ? -80.568  -28.941 28.591  1.00 51.56  ? 348 PHE C C   1 
ATOM   10834 O O   . PHE C 1 288 ? -79.400  -29.097 28.870  1.00 50.53  ? 348 PHE C O   1 
ATOM   10835 C CB  . PHE C 1 288 ? -81.323  -26.938 29.927  1.00 63.20  ? 348 PHE C CB  1 
ATOM   10836 C CG  . PHE C 1 288 ? -81.513  -26.151 28.663  1.00 62.78  ? 348 PHE C CG  1 
ATOM   10837 C CD1 . PHE C 1 288 ? -82.775  -25.948 28.153  1.00 59.15  ? 348 PHE C CD1 1 
ATOM   10838 C CD2 . PHE C 1 288 ? -80.424  -25.620 27.988  1.00 69.79  ? 348 PHE C CD2 1 
ATOM   10839 C CE1 . PHE C 1 288 ? -82.942  -25.219 26.992  1.00 68.90  ? 348 PHE C CE1 1 
ATOM   10840 C CE2 . PHE C 1 288 ? -80.597  -24.894 26.824  1.00 64.37  ? 348 PHE C CE2 1 
ATOM   10841 C CZ  . PHE C 1 288 ? -81.855  -24.696 26.332  1.00 63.26  ? 348 PHE C CZ  1 
ATOM   10842 N N   . ASN C 1 289 ? -81.109  -29.202 27.399  1.00 53.73  ? 349 ASN C N   1 
ATOM   10843 C CA  . ASN C 1 289 ? -80.332  -29.788 26.263  1.00 54.24  ? 349 ASN C CA  1 
ATOM   10844 C C   . ASN C 1 289 ? -80.418  -28.826 25.082  1.00 57.69  ? 349 ASN C C   1 
ATOM   10845 O O   . ASN C 1 289 ? -81.512  -28.641 24.561  1.00 64.14  ? 349 ASN C O   1 
ATOM   10846 C CB  . ASN C 1 289 ? -80.784  -31.212 25.907  1.00 53.52  ? 349 ASN C CB  1 
ATOM   10847 C CG  . ASN C 1 289 ? -79.947  -31.895 24.838  1.00 55.14  ? 349 ASN C CG  1 
ATOM   10848 O OD1 . ASN C 1 289 ? -79.818  -31.378 23.739  1.00 68.91  ? 349 ASN C OD1 1 
ATOM   10849 N ND2 . ASN C 1 289 ? -79.367  -33.050 25.139  1.00 50.84  ? 349 ASN C ND2 1 
ATOM   10850 N N   . ASP C 1 290 ? -79.305  -28.227 24.667  1.00 65.38  ? 350 ASP C N   1 
ATOM   10851 C CA  . ASP C 1 290 ? -79.330  -27.123 23.670  1.00 70.25  ? 350 ASP C CA  1 
ATOM   10852 C C   . ASP C 1 290 ? -79.859  -27.659 22.325  1.00 64.77  ? 350 ASP C C   1 
ATOM   10853 O O   . ASP C 1 290 ? -80.600  -26.935 21.631  1.00 67.08  ? 350 ASP C O   1 
ATOM   10854 C CB  . ASP C 1 290 ? -77.954  -26.459 23.567  1.00 71.00  ? 350 ASP C CB  1 
ATOM   10855 C CG  . ASP C 1 290 ? -78.008  -24.961 23.323  1.00 69.45  ? 350 ASP C CG  1 
ATOM   10856 O OD1 . ASP C 1 290 ? -79.100  -24.378 23.454  1.00 80.36  ? 350 ASP C OD1 1 
ATOM   10857 O OD2 . ASP C 1 290 ? -76.959  -24.389 23.004  1.00 63.60  ? 350 ASP C OD2 1 
ATOM   10858 N N   . ASP C 1 291 ? -79.533  -28.903 22.002  1.00 63.49  ? 351 ASP C N   1 
ATOM   10859 C CA  . ASP C 1 291 ? -79.834  -29.568 20.707  1.00 72.13  ? 351 ASP C CA  1 
ATOM   10860 C C   . ASP C 1 291 ? -81.335  -29.878 20.632  1.00 68.43  ? 351 ASP C C   1 
ATOM   10861 O O   . ASP C 1 291 ? -81.942  -29.611 19.579  1.00 65.95  ? 351 ASP C O   1 
ATOM   10862 C CB  . ASP C 1 291 ? -78.958  -30.814 20.529  1.00 80.41  ? 351 ASP C CB  1 
ATOM   10863 C CG  . ASP C 1 291 ? -77.485  -30.475 20.726  1.00 90.58  ? 351 ASP C CG  1 
ATOM   10864 O OD1 . ASP C 1 291 ? -77.061  -30.396 21.887  1.00 111.48 ? 351 ASP C OD1 1 
ATOM   10865 O OD2 . ASP C 1 291 ? -76.809  -30.117 19.723  1.00 98.69  ? 351 ASP C OD2 1 
ATOM   10866 N N   . ILE C 1 292 ? -81.915  -30.439 21.694  1.00 66.46  ? 352 ILE C N   1 
ATOM   10867 C CA  . ILE C 1 292 ? -83.356  -30.826 21.728  1.00 69.55  ? 352 ILE C CA  1 
ATOM   10868 C C   . ILE C 1 292 ? -84.187  -29.574 22.035  1.00 64.43  ? 352 ILE C C   1 
ATOM   10869 O O   . ILE C 1 292 ? -84.946  -29.128 21.142  1.00 76.65  ? 352 ILE C O   1 
ATOM   10870 C CB  . ILE C 1 292 ? -83.612  -31.977 22.729  1.00 68.71  ? 352 ILE C CB  1 
ATOM   10871 C CG1 . ILE C 1 292 ? -82.774  -33.213 22.397  1.00 63.09  ? 352 ILE C CG1 1 
ATOM   10872 C CG2 . ILE C 1 292 ? -85.091  -32.332 22.793  1.00 73.70  ? 352 ILE C CG2 1 
ATOM   10873 C CD1 . ILE C 1 292 ? -82.656  -34.211 23.521  1.00 66.40  ? 352 ILE C CD1 1 
ATOM   10874 N N   . GLN C 1 293 ? -84.015  -29.020 23.233  1.00 51.54  ? 353 GLN C N   1 
ATOM   10875 C CA  . GLN C 1 293 ? -84.886  -27.962 23.812  1.00 54.57  ? 353 GLN C CA  1 
ATOM   10876 C C   . GLN C 1 293 ? -84.499  -26.574 23.268  1.00 56.60  ? 353 GLN C C   1 
ATOM   10877 O O   . GLN C 1 293 ? -85.406  -25.785 22.964  1.00 61.03  ? 353 GLN C O   1 
ATOM   10878 C CB  . GLN C 1 293 ? -84.832  -28.005 25.345  1.00 56.19  ? 353 GLN C CB  1 
ATOM   10879 C CG  . GLN C 1 293 ? -85.382  -29.302 25.940  1.00 57.92  ? 353 GLN C CG  1 
ATOM   10880 C CD  . GLN C 1 293 ? -85.023  -29.554 27.393  1.00 57.11  ? 353 GLN C CD  1 
ATOM   10881 O OE1 . GLN C 1 293 ? -83.923  -29.251 27.879  1.00 59.73  ? 353 GLN C OE1 1 
ATOM   10882 N NE2 . GLN C 1 293 ? -85.957  -30.173 28.098  1.00 56.15  ? 353 GLN C NE2 1 
ATOM   10883 N N   . GLY C 1 294 ? -83.211  -26.258 23.148  1.00 56.55  ? 354 GLY C N   1 
ATOM   10884 C CA  . GLY C 1 294 ? -82.770  -24.893 22.811  1.00 62.38  ? 354 GLY C CA  1 
ATOM   10885 C C   . GLY C 1 294 ? -83.114  -24.534 21.383  1.00 64.41  ? 354 GLY C C   1 
ATOM   10886 O O   . GLY C 1 294 ? -83.595  -23.394 21.140  1.00 51.93  ? 354 GLY C O   1 
ATOM   10887 N N   . THR C 1 295 ? -82.860  -25.485 20.479  1.00 71.01  ? 355 THR C N   1 
ATOM   10888 C CA  . THR C 1 295 ? -83.105  -25.378 19.016  1.00 65.77  ? 355 THR C CA  1 
ATOM   10889 C C   . THR C 1 295 ? -84.624  -25.325 18.790  1.00 60.63  ? 355 THR C C   1 
ATOM   10890 O O   . THR C 1 295 ? -85.096  -24.371 18.135  1.00 45.05  ? 355 THR C O   1 
ATOM   10891 C CB  . THR C 1 295 ? -82.412  -26.541 18.292  1.00 67.13  ? 355 THR C CB  1 
ATOM   10892 O OG1 . THR C 1 295 ? -81.037  -26.569 18.683  1.00 72.31  ? 355 THR C OG1 1 
ATOM   10893 C CG2 . THR C 1 295 ? -82.485  -26.432 16.788  1.00 67.96  ? 355 THR C CG2 1 
ATOM   10894 N N   . ALA C 1 296 ? -85.360  -26.296 19.352  1.00 54.82  ? 356 ALA C N   1 
ATOM   10895 C CA  . ALA C 1 296 ? -86.840  -26.317 19.376  1.00 47.20  ? 356 ALA C CA  1 
ATOM   10896 C C   . ALA C 1 296 ? -87.345  -24.907 19.694  1.00 39.80  ? 356 ALA C C   1 
ATOM   10897 O O   . ALA C 1 296 ? -88.195  -24.403 18.984  1.00 45.87  ? 356 ALA C O   1 
ATOM   10898 C CB  . ALA C 1 296 ? -87.349  -27.322 20.374  1.00 41.96  ? 356 ALA C CB  1 
ATOM   10899 N N   . SER C 1 297 ? -86.789  -24.284 20.709  1.00 39.17  ? 357 SER C N   1 
ATOM   10900 C CA  . SER C 1 297 ? -87.232  -22.973 21.221  1.00 44.18  ? 357 SER C CA  1 
ATOM   10901 C C   . SER C 1 297 ? -87.069  -21.905 20.142  1.00 44.21  ? 357 SER C C   1 
ATOM   10902 O O   . SER C 1 297 ? -88.038  -21.192 19.887  1.00 42.02  ? 357 SER C O   1 
ATOM   10903 C CB  . SER C 1 297 ? -86.486  -22.613 22.467  1.00 52.76  ? 357 SER C CB  1 
ATOM   10904 O OG  . SER C 1 297 ? -87.124  -21.529 23.113  1.00 57.96  ? 357 SER C OG  1 
ATOM   10905 N N   . VAL C 1 298 ? -85.892  -21.809 19.524  1.00 50.89  ? 358 VAL C N   1 
ATOM   10906 C CA  . VAL C 1 298 ? -85.566  -20.701 18.566  1.00 55.52  ? 358 VAL C CA  1 
ATOM   10907 C C   . VAL C 1 298 ? -86.300  -20.898 17.231  1.00 50.28  ? 358 VAL C C   1 
ATOM   10908 O O   . VAL C 1 298 ? -86.621  -19.881 16.546  1.00 50.42  ? 358 VAL C O   1 
ATOM   10909 C CB  . VAL C 1 298 ? -84.059  -20.575 18.332  1.00 55.89  ? 358 VAL C CB  1 
ATOM   10910 C CG1 . VAL C 1 298 ? -83.501  -21.806 17.626  1.00 59.67  ? 358 VAL C CG1 1 
ATOM   10911 C CG2 . VAL C 1 298 ? -83.751  -19.274 17.596  1.00 55.90  ? 358 VAL C CG2 1 
ATOM   10912 N N   . VAL C 1 299 ? -86.518  -22.158 16.866  1.00 49.17  ? 359 VAL C N   1 
ATOM   10913 C CA  . VAL C 1 299 ? -87.268  -22.536 15.635  1.00 47.47  ? 359 VAL C CA  1 
ATOM   10914 C C   . VAL C 1 299 ? -88.710  -22.063 15.794  1.00 49.44  ? 359 VAL C C   1 
ATOM   10915 O O   . VAL C 1 299 ? -89.194  -21.348 14.899  1.00 49.16  ? 359 VAL C O   1 
ATOM   10916 C CB  . VAL C 1 299 ? -87.188  -24.048 15.356  1.00 44.91  ? 359 VAL C CB  1 
ATOM   10917 C CG1 . VAL C 1 299 ? -88.194  -24.476 14.315  1.00 46.27  ? 359 VAL C CG1 1 
ATOM   10918 C CG2 . VAL C 1 299 ? -85.791  -24.450 14.918  1.00 45.10  ? 359 VAL C CG2 1 
ATOM   10919 N N   . LEU C 1 300 ? -89.351  -22.438 16.902  1.00 49.65  ? 360 LEU C N   1 
ATOM   10920 C CA  . LEU C 1 300 ? -90.746  -22.033 17.188  1.00 50.32  ? 360 LEU C CA  1 
ATOM   10921 C C   . LEU C 1 300 ? -90.837  -20.507 17.129  1.00 48.60  ? 360 LEU C C   1 
ATOM   10922 O O   . LEU C 1 300 ? -91.788  -20.011 16.541  1.00 53.72  ? 360 LEU C O   1 
ATOM   10923 C CB  . LEU C 1 300 ? -91.167  -22.568 18.553  1.00 58.94  ? 360 LEU C CB  1 
ATOM   10924 C CG  . LEU C 1 300 ? -92.663  -22.550 18.853  1.00 57.48  ? 360 LEU C CG  1 
ATOM   10925 C CD1 . LEU C 1 300 ? -92.920  -23.371 20.113  1.00 49.87  ? 360 LEU C CD1 1 
ATOM   10926 C CD2 . LEU C 1 300 ? -93.205  -21.132 18.999  1.00 57.43  ? 360 LEU C CD2 1 
ATOM   10927 N N   . ALA C 1 301 ? -89.846  -19.791 17.646  1.00 48.49  ? 361 ALA C N   1 
ATOM   10928 C CA  . ALA C 1 301 ? -89.797  -18.308 17.627  1.00 52.39  ? 361 ALA C CA  1 
ATOM   10929 C C   . ALA C 1 301 ? -89.699  -17.819 16.189  1.00 49.39  ? 361 ALA C C   1 
ATOM   10930 O O   . ALA C 1 301 ? -90.321  -16.804 15.847  1.00 52.74  ? 361 ALA C O   1 
ATOM   10931 C CB  . ALA C 1 301 ? -88.639  -17.793 18.448  1.00 55.62  ? 361 ALA C CB  1 
ATOM   10932 N N   . GLY C 1 302 ? -88.891  -18.499 15.391  1.00 52.20  ? 362 GLY C N   1 
ATOM   10933 C CA  . GLY C 1 302 ? -88.755  -18.175 13.965  1.00 59.83  ? 362 GLY C CA  1 
ATOM   10934 C C   . GLY C 1 302 ? -90.077  -18.342 13.240  1.00 69.04  ? 362 GLY C C   1 
ATOM   10935 O O   . GLY C 1 302 ? -90.455  -17.416 12.504  1.00 80.54  ? 362 GLY C O   1 
ATOM   10936 N N   . LEU C 1 303 ? -90.754  -19.478 13.446  1.00 65.80  ? 363 LEU C N   1 
ATOM   10937 C CA  . LEU C 1 303 ? -92.094  -19.765 12.878  1.00 56.12  ? 363 LEU C CA  1 
ATOM   10938 C C   . LEU C 1 303 ? -93.040  -18.618 13.245  1.00 54.93  ? 363 LEU C C   1 
ATOM   10939 O O   . LEU C 1 303 ? -93.594  -18.040 12.324  1.00 67.45  ? 363 LEU C O   1 
ATOM   10940 C CB  . LEU C 1 303 ? -92.595  -21.113 13.399  1.00 52.91  ? 363 LEU C CB  1 
ATOM   10941 C CG  . LEU C 1 303 ? -91.737  -22.300 12.982  1.00 54.53  ? 363 LEU C CG  1 
ATOM   10942 C CD1 . LEU C 1 303 ? -92.179  -23.593 13.636  1.00 53.59  ? 363 LEU C CD1 1 
ATOM   10943 C CD2 . LEU C 1 303 ? -91.756  -22.433 11.475  1.00 60.96  ? 363 LEU C CD2 1 
ATOM   10944 N N   . LEU C 1 304 ? -93.178  -18.261 14.523  1.00 50.74  ? 364 LEU C N   1 
ATOM   10945 C CA  . LEU C 1 304 ? -94.110  -17.186 14.978  1.00 53.10  ? 364 LEU C CA  1 
ATOM   10946 C C   . LEU C 1 304 ? -93.747  -15.858 14.293  1.00 54.37  ? 364 LEU C C   1 
ATOM   10947 O O   . LEU C 1 304 ? -94.658  -15.079 13.964  1.00 55.65  ? 364 LEU C O   1 
ATOM   10948 C CB  . LEU C 1 304 ? -94.054  -17.010 16.503  1.00 54.42  ? 364 LEU C CB  1 
ATOM   10949 C CG  . LEU C 1 304 ? -94.514  -18.174 17.382  1.00 51.74  ? 364 LEU C CG  1 
ATOM   10950 C CD1 . LEU C 1 304 ? -94.241  -17.898 18.845  1.00 47.20  ? 364 LEU C CD1 1 
ATOM   10951 C CD2 . LEU C 1 304 ? -95.978  -18.478 17.195  1.00 54.73  ? 364 LEU C CD2 1 
ATOM   10952 N N   . ALA C 1 305 ? -92.456  -15.605 14.091  1.00 64.99  ? 365 ALA C N   1 
ATOM   10953 C CA  . ALA C 1 305 ? -91.918  -14.360 13.482  1.00 65.73  ? 365 ALA C CA  1 
ATOM   10954 C C   . ALA C 1 305 ? -92.205  -14.369 11.982  1.00 59.17  ? 365 ALA C C   1 
ATOM   10955 O O   . ALA C 1 305 ? -92.473  -13.268 11.427  1.00 56.89  ? 365 ALA C O   1 
ATOM   10956 C CB  . ALA C 1 305 ? -90.436  -14.235 13.745  1.00 65.95  ? 365 ALA C CB  1 
ATOM   10957 N N   . ALA C 1 306 ? -92.151  -15.564 11.371  1.00 54.21  ? 366 ALA C N   1 
ATOM   10958 C CA  . ALA C 1 306 ? -92.418  -15.810 9.929   1.00 51.50  ? 366 ALA C CA  1 
ATOM   10959 C C   . ALA C 1 306 ? -93.879  -15.491 9.644   1.00 49.34  ? 366 ALA C C   1 
ATOM   10960 O O   . ALA C 1 306 ? -94.169  -14.813 8.648   1.00 41.82  ? 366 ALA C O   1 
ATOM   10961 C CB  . ALA C 1 306 ? -92.123  -17.241 9.554   1.00 56.87  ? 366 ALA C CB  1 
ATOM   10962 N N   . LEU C 1 307 ? -94.762  -15.930 10.545  1.00 54.44  ? 367 LEU C N   1 
ATOM   10963 C CA  . LEU C 1 307 ? -96.225  -15.857 10.354  1.00 50.02  ? 367 LEU C CA  1 
ATOM   10964 C C   . LEU C 1 307 ? -96.691  -14.427 10.581  1.00 48.91  ? 367 LEU C C   1 
ATOM   10965 O O   . LEU C 1 307 ? -97.805  -14.138 10.192  1.00 67.81  ? 367 LEU C O   1 
ATOM   10966 C CB  . LEU C 1 307 ? -96.903  -16.858 11.279  1.00 48.20  ? 367 LEU C CB  1 
ATOM   10967 C CG  . LEU C 1 307 ? -96.603  -18.326 10.986  1.00 47.08  ? 367 LEU C CG  1 
ATOM   10968 C CD1 . LEU C 1 307 ? -97.419  -19.227 11.877  1.00 52.03  ? 367 LEU C CD1 1 
ATOM   10969 C CD2 . LEU C 1 307 ? -96.878  -18.663 9.547   1.00 50.66  ? 367 LEU C CD2 1 
ATOM   10970 N N   . LYS C 1 308 ? -95.844  -13.557 11.106  1.00 49.31  ? 368 LYS C N   1 
ATOM   10971 C CA  . LYS C 1 308 ? -96.100  -12.100 11.104  1.00 54.55  ? 368 LYS C CA  1 
ATOM   10972 C C   . LYS C 1 308 ? -95.757  -11.507 9.736   1.00 58.86  ? 368 LYS C C   1 
ATOM   10973 O O   . LYS C 1 308 ? -96.417  -10.543 9.355   1.00 73.64  ? 368 LYS C O   1 
ATOM   10974 C CB  . LYS C 1 308 ? -95.321  -11.439 12.231  1.00 59.27  ? 368 LYS C CB  1 
ATOM   10975 C CG  . LYS C 1 308 ? -95.734  -11.921 13.606  1.00 63.28  ? 368 LYS C CG  1 
ATOM   10976 C CD  . LYS C 1 308 ? -94.722  -11.663 14.699  1.00 62.62  ? 368 LYS C CD  1 
ATOM   10977 C CE  . LYS C 1 308 ? -95.149  -10.596 15.679  1.00 65.23  ? 368 LYS C CE  1 
ATOM   10978 N NZ  . LYS C 1 308 ? -94.036  -10.259 16.601  1.00 67.38  ? 368 LYS C NZ  1 
ATOM   10979 N N   . MET C 1 309 ? -94.763  -12.027 9.022   1.00 57.50  ? 369 MET C N   1 
ATOM   10980 C CA  . MET C 1 309 ? -94.412  -11.470 7.690   1.00 73.88  ? 369 MET C CA  1 
ATOM   10981 C C   . MET C 1 309 ? -95.439  -11.935 6.652   1.00 73.53  ? 369 MET C C   1 
ATOM   10982 O O   . MET C 1 309 ? -95.841  -11.100 5.834   1.00 79.20  ? 369 MET C O   1 
ATOM   10983 C CB  . MET C 1 309 ? -93.017  -11.903 7.229   1.00 86.94  ? 369 MET C CB  1 
ATOM   10984 C CG  . MET C 1 309 ? -91.923  -11.487 8.155   1.00 90.31  ? 369 MET C CG  1 
ATOM   10985 S SD  . MET C 1 309 ? -90.429  -12.499 7.986   1.00 92.86  ? 369 MET C SD  1 
ATOM   10986 C CE  . MET C 1 309 ? -89.384  -11.423 7.005   1.00 92.93  ? 369 MET C CE  1 
ATOM   10987 N N   . VAL C 1 310 ? -95.814  -13.221 6.675   1.00 71.70  ? 370 VAL C N   1 
ATOM   10988 C CA  . VAL C 1 310 ? -96.665  -13.875 5.629   1.00 69.08  ? 370 VAL C CA  1 
ATOM   10989 C C   . VAL C 1 310 ? -98.132  -13.981 6.089   1.00 70.77  ? 370 VAL C C   1 
ATOM   10990 O O   . VAL C 1 310 ? -98.994  -14.058 5.204   1.00 81.40  ? 370 VAL C O   1 
ATOM   10991 C CB  . VAL C 1 310 ? -96.103  -15.252 5.219   1.00 70.69  ? 370 VAL C CB  1 
ATOM   10992 C CG1 . VAL C 1 310 ? -94.657  -15.138 4.770   1.00 74.97  ? 370 VAL C CG1 1 
ATOM   10993 C CG2 . VAL C 1 310 ? -96.226  -16.321 6.291   1.00 67.28  ? 370 VAL C CG2 1 
ATOM   10994 N N   . GLY C 1 311 ? -98.412  -13.995 7.401   1.00 67.58  ? 371 GLY C N   1 
ATOM   10995 C CA  . GLY C 1 311 ? -99.767  -14.160 7.962   1.00 59.90  ? 371 GLY C CA  1 
ATOM   10996 C C   . GLY C 1 311 ? -100.089 -15.611 8.290   1.00 68.46  ? 371 GLY C C   1 
ATOM   10997 O O   . GLY C 1 311 ? -99.476  -16.544 7.650   1.00 59.14  ? 371 GLY C O   1 
ATOM   10998 N N   . GLY C 1 312 ? -100.998 -15.804 9.267   1.00 74.54  ? 372 GLY C N   1 
ATOM   10999 C CA  . GLY C 1 312 ? -101.573 -17.111 9.643   1.00 69.29  ? 372 GLY C CA  1 
ATOM   11000 C C   . GLY C 1 312 ? -101.110 -17.589 11.013  1.00 66.87  ? 372 GLY C C   1 
ATOM   11001 O O   . GLY C 1 312 ? -100.411 -16.828 11.740  1.00 50.65  ? 372 GLY C O   1 
ATOM   11002 N N   . THR C 1 313 ? -101.493 -18.820 11.351  1.00 63.53  ? 373 THR C N   1 
ATOM   11003 C CA  . THR C 1 313 ? -101.231 -19.438 12.673  1.00 63.51  ? 373 THR C CA  1 
ATOM   11004 C C   . THR C 1 313 ? -100.472 -20.736 12.453  1.00 51.32  ? 373 THR C C   1 
ATOM   11005 O O   . THR C 1 313 ? -100.410 -21.158 11.313  1.00 42.13  ? 373 THR C O   1 
ATOM   11006 C CB  . THR C 1 313 ? -102.540 -19.703 13.427  1.00 71.27  ? 373 THR C CB  1 
ATOM   11007 O OG1 . THR C 1 313 ? -103.165 -20.824 12.800  1.00 61.38  ? 373 THR C OG1 1 
ATOM   11008 C CG2 . THR C 1 313 ? -103.445 -18.486 13.458  1.00 66.92  ? 373 THR C CG2 1 
ATOM   11009 N N   . LEU C 1 314 ? -99.906  -21.312 13.518  1.00 54.24  ? 374 LEU C N   1 
ATOM   11010 C CA  . LEU C 1 314 ? -99.210  -22.614 13.443  1.00 64.40  ? 374 LEU C CA  1 
ATOM   11011 C C   . LEU C 1 314 ? -100.220 -23.690 13.063  1.00 64.26  ? 374 LEU C C   1 
ATOM   11012 O O   . LEU C 1 314 ? -99.845  -24.585 12.305  1.00 67.43  ? 374 LEU C O   1 
ATOM   11013 C CB  . LEU C 1 314 ? -98.524  -22.941 14.787  1.00 76.65  ? 374 LEU C CB  1 
ATOM   11014 C CG  . LEU C 1 314 ? -97.382  -22.041 15.295  1.00 88.84  ? 374 LEU C CG  1 
ATOM   11015 C CD1 . LEU C 1 314 ? -96.050  -22.793 15.314  1.00 107.26 ? 374 LEU C CD1 1 
ATOM   11016 C CD2 . LEU C 1 314 ? -97.173  -20.767 14.497  1.00 96.99  ? 374 LEU C CD2 1 
ATOM   11017 N N   . ALA C 1 315 ? -101.462 -23.589 13.537  1.00 72.72  ? 375 ALA C N   1 
ATOM   11018 C CA  . ALA C 1 315 ? -102.534 -24.585 13.301  1.00 63.66  ? 375 ALA C CA  1 
ATOM   11019 C C   . ALA C 1 315 ? -102.583 -24.940 11.816  1.00 60.33  ? 375 ALA C C   1 
ATOM   11020 O O   . ALA C 1 315 ? -102.422 -26.143 11.530  1.00 68.01  ? 375 ALA C O   1 
ATOM   11021 C CB  . ALA C 1 315 ? -103.863 -24.072 13.802  1.00 66.08  ? 375 ALA C CB  1 
ATOM   11022 N N   . GLU C 1 316 ? -102.743 -23.945 10.935  1.00 62.88  ? 376 GLU C N   1 
ATOM   11023 C CA  . GLU C 1 316 ? -102.990 -24.139 9.471   1.00 79.73  ? 376 GLU C CA  1 
ATOM   11024 C C   . GLU C 1 316 ? -101.802 -24.785 8.735   1.00 78.36  ? 376 GLU C C   1 
ATOM   11025 O O   . GLU C 1 316 ? -102.061 -25.444 7.705   1.00 77.35  ? 376 GLU C O   1 
ATOM   11026 C CB  . GLU C 1 316 ? -103.191 -22.824 8.712   1.00 82.22  ? 376 GLU C CB  1 
ATOM   11027 C CG  . GLU C 1 316 ? -104.508 -22.156 8.962   1.00 88.41  ? 376 GLU C CG  1 
ATOM   11028 C CD  . GLU C 1 316 ? -104.364 -21.102 10.020  1.00 97.75  ? 376 GLU C CD  1 
ATOM   11029 O OE1 . GLU C 1 316 ? -104.960 -21.327 11.091  1.00 108.33 ? 376 GLU C OE1 1 
ATOM   11030 O OE2 . GLU C 1 316 ? -103.602 -20.120 9.786   1.00 97.09  ? 376 GLU C OE2 1 
ATOM   11031 N N   . GLN C 1 317 ? -100.567 -24.564 9.203   1.00 66.35  ? 377 GLN C N   1 
ATOM   11032 C CA  . GLN C 1 317 ? -99.341  -24.917 8.442   1.00 61.45  ? 377 GLN C CA  1 
ATOM   11033 C C   . GLN C 1 317 ? -99.163  -26.439 8.388   1.00 61.68  ? 377 GLN C C   1 
ATOM   11034 O O   . GLN C 1 317 ? -99.641  -27.164 9.307   1.00 51.98  ? 377 GLN C O   1 
ATOM   11035 C CB  . GLN C 1 317 ? -98.096  -24.282 9.056   1.00 57.28  ? 377 GLN C CB  1 
ATOM   11036 C CG  . GLN C 1 317 ? -98.235  -22.808 9.409   1.00 59.31  ? 377 GLN C CG  1 
ATOM   11037 C CD  . GLN C 1 317 ? -98.532  -21.963 8.208   1.00 55.18  ? 377 GLN C CD  1 
ATOM   11038 O OE1 . GLN C 1 317 ? -97.921  -22.131 7.155   1.00 53.97  ? 377 GLN C OE1 1 
ATOM   11039 N NE2 . GLN C 1 317 ? -99.441  -21.014 8.381   1.00 54.60  ? 377 GLN C NE2 1 
ATOM   11040 N N   . THR C 1 318 ? -98.488  -26.896 7.328   1.00 65.13  ? 378 THR C N   1 
ATOM   11041 C CA  . THR C 1 318 ? -98.022  -28.300 7.181   1.00 64.67  ? 378 THR C CA  1 
ATOM   11042 C C   . THR C 1 318 ? -96.488  -28.294 7.160   1.00 72.16  ? 378 THR C C   1 
ATOM   11043 O O   . THR C 1 318 ? -95.893  -27.559 6.293   1.00 54.84  ? 378 THR C O   1 
ATOM   11044 C CB  . THR C 1 318 ? -98.615  -28.992 5.955   1.00 61.14  ? 378 THR C CB  1 
ATOM   11045 O OG1 . THR C 1 318 ? -100.024 -28.788 5.996   1.00 67.61  ? 378 THR C OG1 1 
ATOM   11046 C CG2 . THR C 1 318 ? -98.313  -30.472 5.918   1.00 57.93  ? 378 THR C CG2 1 
ATOM   11047 N N   . TYR C 1 319 ? -95.902  -29.083 8.079   1.00 68.72  ? 379 TYR C N   1 
ATOM   11048 C CA  . TYR C 1 319 ? -94.459  -29.122 8.414   1.00 60.72  ? 379 TYR C CA  1 
ATOM   11049 C C   . TYR C 1 319 ? -93.825  -30.392 7.838   1.00 58.24  ? 379 TYR C C   1 
ATOM   11050 O O   . TYR C 1 319 ? -94.304  -31.490 8.155   1.00 63.51  ? 379 TYR C O   1 
ATOM   11051 C CB  . TYR C 1 319 ? -94.255  -29.098 9.931   1.00 56.49  ? 379 TYR C CB  1 
ATOM   11052 C CG  . TYR C 1 319 ? -94.987  -27.997 10.629  1.00 49.21  ? 379 TYR C CG  1 
ATOM   11053 C CD1 . TYR C 1 319 ? -94.425  -26.739 10.749  1.00 56.25  ? 379 TYR C CD1 1 
ATOM   11054 C CD2 . TYR C 1 319 ? -96.233  -28.210 11.166  1.00 49.46  ? 379 TYR C CD2 1 
ATOM   11055 C CE1 . TYR C 1 319 ? -95.094  -25.712 11.397  1.00 55.18  ? 379 TYR C CE1 1 
ATOM   11056 C CE2 . TYR C 1 319 ? -96.938  -27.186 11.782  1.00 58.55  ? 379 TYR C CE2 1 
ATOM   11057 C CZ  . TYR C 1 319 ? -96.365  -25.921 11.881  1.00 53.23  ? 379 TYR C CZ  1 
ATOM   11058 O OH  . TYR C 1 319 ? -96.930  -24.834 12.470  1.00 45.79  ? 379 TYR C OH  1 
ATOM   11059 N N   . LEU C 1 320 ? -92.751  -30.226 7.068   1.00 55.53  ? 380 LEU C N   1 
ATOM   11060 C CA  . LEU C 1 320 ? -91.869  -31.334 6.655   1.00 61.76  ? 380 LEU C CA  1 
ATOM   11061 C C   . LEU C 1 320 ? -90.445  -31.093 7.176   1.00 65.86  ? 380 LEU C C   1 
ATOM   11062 O O   . LEU C 1 320 ? -89.856  -30.043 6.838   1.00 60.21  ? 380 LEU C O   1 
ATOM   11063 C CB  . LEU C 1 320 ? -91.890  -31.450 5.130   1.00 66.98  ? 380 LEU C CB  1 
ATOM   11064 C CG  . LEU C 1 320 ? -91.251  -32.732 4.591   1.00 65.23  ? 380 LEU C CG  1 
ATOM   11065 C CD1 . LEU C 1 320 ? -91.816  -33.962 5.300   1.00 60.38  ? 380 LEU C CD1 1 
ATOM   11066 C CD2 . LEU C 1 320 ? -91.441  -32.840 3.071   1.00 71.08  ? 380 LEU C CD2 1 
ATOM   11067 N N   . PHE C 1 321 ? -89.923  -32.080 7.914   1.00 64.49  ? 381 PHE C N   1 
ATOM   11068 C CA  . PHE C 1 321 ? -88.531  -32.186 8.420   1.00 63.25  ? 381 PHE C CA  1 
ATOM   11069 C C   . PHE C 1 321 ? -87.703  -33.183 7.582   1.00 59.55  ? 381 PHE C C   1 
ATOM   11070 O O   . PHE C 1 321 ? -88.154  -34.321 7.314   1.00 49.98  ? 381 PHE C O   1 
ATOM   11071 C CB  . PHE C 1 321 ? -88.526  -32.649 9.881   1.00 65.57  ? 381 PHE C CB  1 
ATOM   11072 C CG  . PHE C 1 321 ? -89.031  -31.626 10.859  1.00 68.36  ? 381 PHE C CG  1 
ATOM   11073 C CD1 . PHE C 1 321 ? -88.190  -30.647 11.360  1.00 75.39  ? 381 PHE C CD1 1 
ATOM   11074 C CD2 . PHE C 1 321 ? -90.332  -31.663 11.312  1.00 66.39  ? 381 PHE C CD2 1 
ATOM   11075 C CE1 . PHE C 1 321 ? -88.671  -29.684 12.235  1.00 77.54  ? 381 PHE C CE1 1 
ATOM   11076 C CE2 . PHE C 1 321 ? -90.809  -30.705 12.195  1.00 66.85  ? 381 PHE C CE2 1 
ATOM   11077 C CZ  . PHE C 1 321 ? -89.980  -29.719 12.653  1.00 72.84  ? 381 PHE C CZ  1 
ATOM   11078 N N   . LEU C 1 322 ? -86.488  -32.786 7.206   1.00 54.08  ? 382 LEU C N   1 
ATOM   11079 C CA  . LEU C 1 322 ? -85.415  -33.755 6.928   1.00 51.39  ? 382 LEU C CA  1 
ATOM   11080 C C   . LEU C 1 322 ? -84.602  -33.900 8.222   1.00 56.34  ? 382 LEU C C   1 
ATOM   11081 O O   . LEU C 1 322 ? -84.140  -32.866 8.761   1.00 57.25  ? 382 LEU C O   1 
ATOM   11082 C CB  . LEU C 1 322 ? -84.571  -33.277 5.748   1.00 56.13  ? 382 LEU C CB  1 
ATOM   11083 C CG  . LEU C 1 322 ? -83.468  -34.241 5.292   1.00 63.45  ? 382 LEU C CG  1 
ATOM   11084 C CD1 . LEU C 1 322 ? -84.027  -35.590 4.880   1.00 59.85  ? 382 LEU C CD1 1 
ATOM   11085 C CD2 . LEU C 1 322 ? -82.655  -33.651 4.169   1.00 62.08  ? 382 LEU C CD2 1 
ATOM   11086 N N   . GLY C 1 323 ? -84.484  -35.135 8.718   1.00 64.34  ? 383 GLY C N   1 
ATOM   11087 C CA  . GLY C 1 323 ? -83.697  -35.494 9.913   1.00 75.01  ? 383 GLY C CA  1 
ATOM   11088 C C   . GLY C 1 323 ? -84.572  -35.643 11.150  1.00 86.36  ? 383 GLY C C   1 
ATOM   11089 O O   . GLY C 1 323 ? -85.015  -34.605 11.678  1.00 88.18  ? 383 GLY C O   1 
ATOM   11090 N N   . ALA C 1 324 ? -84.811  -36.891 11.592  1.00 86.03  ? 384 ALA C N   1 
ATOM   11091 C CA  . ALA C 1 324 ? -85.677  -37.256 12.743  1.00 73.79  ? 384 ALA C CA  1 
ATOM   11092 C C   . ALA C 1 324 ? -84.798  -37.663 13.923  1.00 74.28  ? 384 ALA C C   1 
ATOM   11093 O O   . ALA C 1 324 ? -84.967  -38.781 14.434  1.00 85.24  ? 384 ALA C O   1 
ATOM   11094 C CB  . ALA C 1 324 ? -86.632  -38.371 12.386  1.00 66.17  ? 384 ALA C CB  1 
ATOM   11095 N N   . GLY C 1 325 ? -83.895  -36.782 14.335  1.00 77.35  ? 385 GLY C N   1 
ATOM   11096 C CA  . GLY C 1 325 ? -83.007  -37.039 15.479  1.00 85.59  ? 385 GLY C CA  1 
ATOM   11097 C C   . GLY C 1 325 ? -83.486  -36.287 16.697  1.00 83.52  ? 385 GLY C C   1 
ATOM   11098 O O   . GLY C 1 325 ? -84.718  -36.138 16.845  1.00 78.29  ? 385 GLY C O   1 
ATOM   11099 N N   . GLU C 1 326 ? -82.527  -35.825 17.506  1.00 80.87  ? 386 GLU C N   1 
ATOM   11100 C CA  . GLU C 1 326 ? -82.754  -34.930 18.669  1.00 81.27  ? 386 GLU C CA  1 
ATOM   11101 C C   . GLU C 1 326 ? -83.533  -33.693 18.194  1.00 71.17  ? 386 GLU C C   1 
ATOM   11102 O O   . GLU C 1 326 ? -84.710  -33.548 18.537  1.00 75.85  ? 386 GLU C O   1 
ATOM   11103 C CB  . GLU C 1 326 ? -81.430  -34.513 19.316  1.00 82.37  ? 386 GLU C CB  1 
ATOM   11104 C CG  . GLU C 1 326 ? -80.444  -35.639 19.567  1.00 75.96  ? 386 GLU C CG  1 
ATOM   11105 C CD  . GLU C 1 326 ? -79.156  -35.174 20.241  1.00 85.53  ? 386 GLU C CD  1 
ATOM   11106 O OE1 . GLU C 1 326 ? -78.095  -35.651 19.840  1.00 113.34 ? 386 GLU C OE1 1 
ATOM   11107 O OE2 . GLU C 1 326 ? -79.190  -34.284 21.134  1.00 96.90  ? 386 GLU C OE2 1 
ATOM   11108 N N   . ALA C 1 327 ? -82.899  -32.823 17.425  1.00 66.86  ? 387 ALA C N   1 
ATOM   11109 C CA  . ALA C 1 327 ? -83.471  -31.525 17.007  1.00 76.39  ? 387 ALA C CA  1 
ATOM   11110 C C   . ALA C 1 327 ? -84.758  -31.776 16.212  1.00 72.05  ? 387 ALA C C   1 
ATOM   11111 O O   . ALA C 1 327 ? -85.731  -31.049 16.428  1.00 68.36  ? 387 ALA C O   1 
ATOM   11112 C CB  . ALA C 1 327 ? -82.450  -30.740 16.209  1.00 81.22  ? 387 ALA C CB  1 
ATOM   11113 N N   . GLY C 1 328 ? -84.753  -32.784 15.331  1.00 77.83  ? 388 GLY C N   1 
ATOM   11114 C CA  . GLY C 1 328 ? -85.943  -33.177 14.553  1.00 78.60  ? 388 GLY C CA  1 
ATOM   11115 C C   . GLY C 1 328 ? -87.176  -33.300 15.439  1.00 70.85  ? 388 GLY C C   1 
ATOM   11116 O O   . GLY C 1 328 ? -88.008  -32.358 15.438  1.00 53.73  ? 388 GLY C O   1 
ATOM   11117 N N   . THR C 1 329 ? -87.268  -34.405 16.191  1.00 60.74  ? 389 THR C N   1 
ATOM   11118 C CA  . THR C 1 329 ? -88.432  -34.739 17.050  1.00 64.59  ? 389 THR C CA  1 
ATOM   11119 C C   . THR C 1 329 ? -88.613  -33.633 18.092  1.00 60.24  ? 389 THR C C   1 
ATOM   11120 O O   . THR C 1 329 ? -89.755  -33.262 18.351  1.00 55.86  ? 389 THR C O   1 
ATOM   11121 C CB  . THR C 1 329 ? -88.304  -36.140 17.667  1.00 66.95  ? 389 THR C CB  1 
ATOM   11122 O OG1 . THR C 1 329 ? -87.178  -36.181 18.541  1.00 69.77  ? 389 THR C OG1 1 
ATOM   11123 C CG2 . THR C 1 329 ? -88.171  -37.206 16.606  1.00 67.80  ? 389 THR C CG2 1 
ATOM   11124 N N   . GLY C 1 330 ? -87.515  -33.129 18.650  1.00 64.03  ? 390 GLY C N   1 
ATOM   11125 C CA  . GLY C 1 330 ? -87.509  -32.045 19.652  1.00 68.75  ? 390 GLY C CA  1 
ATOM   11126 C C   . GLY C 1 330 ? -88.222  -30.791 19.169  1.00 63.61  ? 390 GLY C C   1 
ATOM   11127 O O   . GLY C 1 330 ? -89.112  -30.302 19.869  1.00 62.69  ? 390 GLY C O   1 
ATOM   11128 N N   . ILE C 1 331 ? -87.857  -30.281 18.000  1.00 68.38  ? 391 ILE C N   1 
ATOM   11129 C CA  . ILE C 1 331 ? -88.505  -29.075 17.405  1.00 68.24  ? 391 ILE C CA  1 
ATOM   11130 C C   . ILE C 1 331 ? -89.981  -29.411 17.197  1.00 61.23  ? 391 ILE C C   1 
ATOM   11131 O O   . ILE C 1 331 ? -90.843  -28.617 17.614  1.00 85.11  ? 391 ILE C O   1 
ATOM   11132 C CB  . ILE C 1 331 ? -87.813  -28.617 16.102  1.00 66.91  ? 391 ILE C CB  1 
ATOM   11133 C CG1 . ILE C 1 331 ? -86.297  -28.468 16.256  1.00 66.89  ? 391 ILE C CG1 1 
ATOM   11134 C CG2 . ILE C 1 331 ? -88.416  -27.321 15.607  1.00 62.87  ? 391 ILE C CG2 1 
ATOM   11135 C CD1 . ILE C 1 331 ? -85.580  -28.236 14.962  1.00 64.66  ? 391 ILE C CD1 1 
ATOM   11136 N N   . ALA C 1 332 ? -90.255  -30.560 16.598  1.00 57.71  ? 392 ALA C N   1 
ATOM   11137 C CA  . ALA C 1 332 ? -91.619  -30.998 16.232  1.00 63.93  ? 392 ALA C CA  1 
ATOM   11138 C C   . ALA C 1 332 ? -92.508  -31.009 17.478  1.00 67.40  ? 392 ALA C C   1 
ATOM   11139 O O   . ALA C 1 332 ? -93.610  -30.460 17.432  1.00 70.67  ? 392 ALA C O   1 
ATOM   11140 C CB  . ALA C 1 332 ? -91.572  -32.362 15.599  1.00 65.89  ? 392 ALA C CB  1 
ATOM   11141 N N   . GLU C 1 333 ? -92.045  -31.637 18.553  1.00 69.01  ? 393 GLU C N   1 
ATOM   11142 C CA  . GLU C 1 333 ? -92.826  -31.779 19.801  1.00 66.13  ? 393 GLU C CA  1 
ATOM   11143 C C   . GLU C 1 333 ? -93.151  -30.397 20.386  1.00 55.58  ? 393 GLU C C   1 
ATOM   11144 O O   . GLU C 1 333 ? -94.245  -30.242 20.910  1.00 48.66  ? 393 GLU C O   1 
ATOM   11145 C CB  . GLU C 1 333 ? -92.070  -32.659 20.791  1.00 62.14  ? 393 GLU C CB  1 
ATOM   11146 C CG  . GLU C 1 333 ? -92.887  -33.006 22.034  1.00 65.91  ? 393 GLU C CG  1 
ATOM   11147 C CD  . GLU C 1 333 ? -94.138  -33.834 21.795  1.00 64.35  ? 393 GLU C CD  1 
ATOM   11148 O OE1 . GLU C 1 333 ? -94.246  -34.469 20.738  1.00 65.58  ? 393 GLU C OE1 1 
ATOM   11149 O OE2 . GLU C 1 333 ? -95.009  -33.806 22.655  1.00 67.61  ? 393 GLU C OE2 1 
ATOM   11150 N N   . LEU C 1 334 ? -92.237  -29.436 20.304  1.00 51.66  ? 394 LEU C N   1 
ATOM   11151 C CA  . LEU C 1 334 ? -92.476  -28.079 20.848  1.00 51.24  ? 394 LEU C CA  1 
ATOM   11152 C C   . LEU C 1 334 ? -93.460  -27.336 19.945  1.00 51.11  ? 394 LEU C C   1 
ATOM   11153 O O   . LEU C 1 334 ? -94.152  -26.438 20.412  1.00 45.54  ? 394 LEU C O   1 
ATOM   11154 C CB  . LEU C 1 334 ? -91.168  -27.305 20.974  1.00 52.49  ? 394 LEU C CB  1 
ATOM   11155 C CG  . LEU C 1 334 ? -91.283  -26.088 21.885  1.00 60.04  ? 394 LEU C CG  1 
ATOM   11156 C CD1 . LEU C 1 334 ? -91.476  -26.518 23.334  1.00 63.01  ? 394 LEU C CD1 1 
ATOM   11157 C CD2 . LEU C 1 334 ? -90.076  -25.165 21.738  1.00 64.62  ? 394 LEU C CD2 1 
ATOM   11158 N N   . ILE C 1 335 ? -93.529  -27.703 18.676  1.00 64.87  ? 395 ILE C N   1 
ATOM   11159 C CA  . ILE C 1 335 ? -94.468  -27.051 17.717  1.00 68.59  ? 395 ILE C CA  1 
ATOM   11160 C C   . ILE C 1 335 ? -95.876  -27.540 18.061  1.00 65.68  ? 395 ILE C C   1 
ATOM   11161 O O   . ILE C 1 335 ? -96.731  -26.674 18.321  1.00 66.48  ? 395 ILE C O   1 
ATOM   11162 C CB  . ILE C 1 335 ? -94.045  -27.330 16.258  1.00 63.24  ? 395 ILE C CB  1 
ATOM   11163 C CG1 . ILE C 1 335 ? -92.705  -26.659 15.949  1.00 70.29  ? 395 ILE C CG1 1 
ATOM   11164 C CG2 . ILE C 1 335 ? -95.129  -26.925 15.288  1.00 67.96  ? 395 ILE C CG2 1 
ATOM   11165 C CD1 . ILE C 1 335 ? -92.204  -26.820 14.520  1.00 73.98  ? 395 ILE C CD1 1 
ATOM   11166 N N   . ALA C 1 336 ? -96.065  -28.870 18.108  1.00 64.28  ? 396 ALA C N   1 
ATOM   11167 C CA  . ALA C 1 336 ? -97.339  -29.552 18.423  1.00 65.00  ? 396 ALA C CA  1 
ATOM   11168 C C   . ALA C 1 336 ? -97.853  -29.032 19.767  1.00 63.20  ? 396 ALA C C   1 
ATOM   11169 O O   . ALA C 1 336 ? -99.050  -28.745 19.871  1.00 67.56  ? 396 ALA C O   1 
ATOM   11170 C CB  . ALA C 1 336 ? -97.135  -31.050 18.418  1.00 67.75  ? 396 ALA C CB  1 
ATOM   11171 N N   . LEU C 1 337 ? -96.977  -28.877 20.756  1.00 63.57  ? 397 LEU C N   1 
ATOM   11172 C CA  . LEU C 1 337 ? -97.352  -28.319 22.082  1.00 63.48  ? 397 LEU C CA  1 
ATOM   11173 C C   . LEU C 1 337 ? -97.900  -26.893 21.901  1.00 61.07  ? 397 LEU C C   1 
ATOM   11174 O O   . LEU C 1 337 ? -98.984  -26.630 22.401  1.00 66.83  ? 397 LEU C O   1 
ATOM   11175 C CB  . LEU C 1 337 ? -96.141  -28.348 23.021  1.00 72.61  ? 397 LEU C CB  1 
ATOM   11176 C CG  . LEU C 1 337 ? -96.441  -28.075 24.506  1.00 79.40  ? 397 LEU C CG  1 
ATOM   11177 C CD1 . LEU C 1 337 ? -97.557  -28.973 25.024  1.00 83.16  ? 397 LEU C CD1 1 
ATOM   11178 C CD2 . LEU C 1 337 ? -95.202  -28.237 25.367  1.00 81.35  ? 397 LEU C CD2 1 
ATOM   11179 N N   . GLU C 1 338 ? -97.200  -26.005 21.193  1.00 56.26  ? 398 GLU C N   1 
ATOM   11180 C CA  . GLU C 1 338 ? -97.648  -24.597 21.031  1.00 51.95  ? 398 GLU C CA  1 
ATOM   11181 C C   . GLU C 1 338 ? -99.022  -24.594 20.350  1.00 60.85  ? 398 GLU C C   1 
ATOM   11182 O O   . GLU C 1 338 ? -99.852  -23.725 20.704  1.00 62.28  ? 398 GLU C O   1 
ATOM   11183 C CB  . GLU C 1 338 ? -96.662  -23.798 20.200  1.00 54.50  ? 398 GLU C CB  1 
ATOM   11184 C CG  . GLU C 1 338 ? -97.016  -22.319 20.155  1.00 58.00  ? 398 GLU C CG  1 
ATOM   11185 C CD  . GLU C 1 338 ? -97.208  -21.638 21.500  1.00 61.26  ? 398 GLU C CD  1 
ATOM   11186 O OE1 . GLU C 1 338 ? -96.234  -21.078 22.045  1.00 75.97  ? 398 GLU C OE1 1 
ATOM   11187 O OE2 . GLU C 1 338 ? -98.322  -21.592 21.981  1.00 71.94  ? 398 GLU C OE2 1 
ATOM   11188 N N   . ILE C 1 339 ? -99.263  -25.532 19.422  1.00 65.09  ? 399 ILE C N   1 
ATOM   11189 C CA  . ILE C 1 339 ? -100.567 -25.713 18.709  1.00 67.16  ? 399 ILE C CA  1 
ATOM   11190 C C   . ILE C 1 339 ? -101.640 -26.107 19.737  1.00 71.20  ? 399 ILE C C   1 
ATOM   11191 O O   . ILE C 1 339 ? -102.702 -25.443 19.785  1.00 64.94  ? 399 ILE C O   1 
ATOM   11192 C CB  . ILE C 1 339 ? -100.450 -26.747 17.567  1.00 74.44  ? 399 ILE C CB  1 
ATOM   11193 C CG1 . ILE C 1 339 ? -99.683  -26.184 16.363  1.00 69.55  ? 399 ILE C CG1 1 
ATOM   11194 C CG2 . ILE C 1 339 ? -101.820 -27.292 17.169  1.00 73.19  ? 399 ILE C CG2 1 
ATOM   11195 C CD1 . ILE C 1 339 ? -99.399  -27.203 15.268  1.00 71.07  ? 399 ILE C CD1 1 
ATOM   11196 N N   . SER C 1 340 ? -101.360 -27.132 20.552  1.00 66.78  ? 400 SER C N   1 
ATOM   11197 C CA  . SER C 1 340 ? -102.249 -27.593 21.646  1.00 67.47  ? 400 SER C CA  1 
ATOM   11198 C C   . SER C 1 340 ? -102.627 -26.414 22.569  1.00 61.68  ? 400 SER C C   1 
ATOM   11199 O O   . SER C 1 340 ? -103.752 -26.346 22.999  1.00 57.98  ? 400 SER C O   1 
ATOM   11200 C CB  . SER C 1 340 ? -101.622 -28.745 22.390  1.00 59.39  ? 400 SER C CB  1 
ATOM   11201 O OG  . SER C 1 340 ? -101.838 -28.620 23.782  1.00 60.45  ? 400 SER C OG  1 
ATOM   11202 N N   . LYS C 1 341 ? -101.720 -25.501 22.866  1.00 70.09  ? 401 LYS C N   1 
ATOM   11203 C CA  . LYS C 1 341 ? -102.000 -24.363 23.784  1.00 75.63  ? 401 LYS C CA  1 
ATOM   11204 C C   . LYS C 1 341 ? -102.818 -23.303 23.016  1.00 70.00  ? 401 LYS C C   1 
ATOM   11205 O O   . LYS C 1 341 ? -103.536 -22.533 23.653  1.00 77.21  ? 401 LYS C O   1 
ATOM   11206 C CB  . LYS C 1 341 ? -100.707 -23.817 24.422  1.00 76.52  ? 401 LYS C CB  1 
ATOM   11207 C CG  . LYS C 1 341 ? -99.834  -24.804 25.212  1.00 72.43  ? 401 LYS C CG  1 
ATOM   11208 C CD  . LYS C 1 341 ? -100.340 -25.255 26.580  1.00 76.07  ? 401 LYS C CD  1 
ATOM   11209 C CE  . LYS C 1 341 ? -99.330  -25.204 27.717  1.00 71.84  ? 401 LYS C CE  1 
ATOM   11210 N NZ  . LYS C 1 341 ? -100.032 -25.088 29.019  1.00 71.40  ? 401 LYS C NZ  1 
ATOM   11211 N N   . GLN C 1 342 ? -102.766 -23.276 21.693  1.00 60.12  ? 402 GLN C N   1 
ATOM   11212 C CA  . GLN C 1 342 ? -103.487 -22.251 20.898  1.00 68.35  ? 402 GLN C CA  1 
ATOM   11213 C C   . GLN C 1 342 ? -104.854 -22.752 20.431  1.00 66.75  ? 402 GLN C C   1 
ATOM   11214 O O   . GLN C 1 342 ? -105.729 -21.920 20.190  1.00 68.09  ? 402 GLN C O   1 
ATOM   11215 C CB  . GLN C 1 342 ? -102.592 -21.829 19.743  1.00 77.08  ? 402 GLN C CB  1 
ATOM   11216 C CG  . GLN C 1 342 ? -101.837 -20.583 20.146  1.00 71.92  ? 402 GLN C CG  1 
ATOM   11217 C CD  . GLN C 1 342 ? -100.706 -20.316 19.193  1.00 70.92  ? 402 GLN C CD  1 
ATOM   11218 O OE1 . GLN C 1 342 ? -100.898 -20.200 17.977  1.00 62.18  ? 402 GLN C OE1 1 
ATOM   11219 N NE2 . GLN C 1 342 ? -99.515  -20.225 19.771  1.00 79.35  ? 402 GLN C NE2 1 
ATOM   11220 N N   . THR C 1 343 ? -105.022 -24.064 20.300  1.00 76.86  ? 403 THR C N   1 
ATOM   11221 C CA  . THR C 1 343 ? -106.257 -24.716 19.779  1.00 72.63  ? 403 THR C CA  1 
ATOM   11222 C C   . THR C 1 343 ? -107.026 -25.430 20.895  1.00 68.79  ? 403 THR C C   1 
ATOM   11223 O O   . THR C 1 343 ? -108.227 -25.620 20.765  1.00 74.14  ? 403 THR C O   1 
ATOM   11224 C CB  . THR C 1 343 ? -105.925 -25.748 18.699  1.00 75.02  ? 403 THR C CB  1 
ATOM   11225 O OG1 . THR C 1 343 ? -105.212 -26.825 19.327  1.00 72.60  ? 403 THR C OG1 1 
ATOM   11226 C CG2 . THR C 1 343 ? -105.199 -25.130 17.523  1.00 64.82  ? 403 THR C CG2 1 
ATOM   11227 N N   . ASN C 1 344 ? -106.330 -25.867 21.931  1.00 72.09  ? 404 ASN C N   1 
ATOM   11228 C CA  . ASN C 1 344 ? -106.877 -26.634 23.076  1.00 72.92  ? 404 ASN C CA  1 
ATOM   11229 C C   . ASN C 1 344 ? -107.159 -28.070 22.614  1.00 67.43  ? 404 ASN C C   1 
ATOM   11230 O O   . ASN C 1 344 ? -107.818 -28.819 23.360  1.00 62.26  ? 404 ASN C O   1 
ATOM   11231 C CB  . ASN C 1 344 ? -108.069 -25.931 23.728  1.00 68.85  ? 404 ASN C CB  1 
ATOM   11232 C CG  . ASN C 1 344 ? -108.301 -26.417 25.144  1.00 78.04  ? 404 ASN C CG  1 
ATOM   11233 O OD1 . ASN C 1 344 ? -107.548 -26.087 26.056  1.00 85.05  ? 404 ASN C OD1 1 
ATOM   11234 N ND2 . ASN C 1 344 ? -109.306 -27.259 25.328  1.00 95.35  ? 404 ASN C ND2 1 
ATOM   11235 N N   . ALA C 1 345 ? -106.578 -28.497 21.499  1.00 56.91  ? 405 ALA C N   1 
ATOM   11236 C CA  . ALA C 1 345 ? -106.623 -29.921 21.122  1.00 61.39  ? 405 ALA C CA  1 
ATOM   11237 C C   . ALA C 1 345 ? -105.627 -30.717 21.967  1.00 70.35  ? 405 ALA C C   1 
ATOM   11238 O O   . ALA C 1 345 ? -104.666 -30.147 22.502  1.00 55.92  ? 405 ALA C O   1 
ATOM   11239 C CB  . ALA C 1 345 ? -106.368 -30.062 19.654  1.00 60.80  ? 405 ALA C CB  1 
ATOM   11240 N N   . PRO C 1 346 ? -105.851 -32.046 22.147  1.00 82.43  ? 406 PRO C N   1 
ATOM   11241 C CA  . PRO C 1 346 ? -104.837 -32.920 22.751  1.00 89.37  ? 406 PRO C CA  1 
ATOM   11242 C C   . PRO C 1 346 ? -103.568 -32.937 21.888  1.00 93.82  ? 406 PRO C C   1 
ATOM   11243 O O   . PRO C 1 346 ? -103.674 -32.801 20.662  1.00 87.55  ? 406 PRO C O   1 
ATOM   11244 C CB  . PRO C 1 346 ? -105.488 -34.316 22.808  1.00 92.40  ? 406 PRO C CB  1 
ATOM   11245 C CG  . PRO C 1 346 ? -106.691 -34.223 21.867  1.00 82.03  ? 406 PRO C CG  1 
ATOM   11246 C CD  . PRO C 1 346 ? -107.100 -32.761 21.826  1.00 73.10  ? 406 PRO C CD  1 
ATOM   11247 N N   . ILE C 1 347 ? -102.403 -33.126 22.511  1.00 97.03  ? 407 ILE C N   1 
ATOM   11248 C CA  . ILE C 1 347 ? -101.097 -33.204 21.791  1.00 91.13  ? 407 ILE C CA  1 
ATOM   11249 C C   . ILE C 1 347 ? -101.210 -34.286 20.702  1.00 86.53  ? 407 ILE C C   1 
ATOM   11250 O O   . ILE C 1 347 ? -100.864 -33.977 19.555  1.00 75.36  ? 407 ILE C O   1 
ATOM   11251 C CB  . ILE C 1 347 ? -99.921  -33.435 22.776  1.00 92.11  ? 407 ILE C CB  1 
ATOM   11252 C CG1 . ILE C 1 347 ? -98.578  -33.056 22.148  1.00 82.27  ? 407 ILE C CG1 1 
ATOM   11253 C CG2 . ILE C 1 347 ? -99.902  -34.861 23.343  1.00 95.89  ? 407 ILE C CG2 1 
ATOM   11254 C CD1 . ILE C 1 347 ? -98.365  -31.580 22.051  1.00 81.49  ? 407 ILE C CD1 1 
ATOM   11255 N N   . GLU C 1 348 ? -101.791 -35.455 21.019  1.00 88.62  ? 408 GLU C N   1 
ATOM   11256 C CA  . GLU C 1 348 ? -101.807 -36.658 20.150  1.00 85.92  ? 408 GLU C CA  1 
ATOM   11257 C C   . GLU C 1 348 ? -102.677 -36.378 18.919  1.00 86.78  ? 408 GLU C C   1 
ATOM   11258 O O   . GLU C 1 348 ? -102.777 -37.282 18.089  1.00 95.44  ? 408 GLU C O   1 
ATOM   11259 C CB  . GLU C 1 348 ? -102.218 -37.906 20.959  1.00 96.71  ? 408 GLU C CB  1 
ATOM   11260 C CG  . GLU C 1 348 ? -101.675 -37.926 22.407  1.00 115.19 ? 408 GLU C CG  1 
ATOM   11261 C CD  . GLU C 1 348 ? -100.929 -39.159 22.919  1.00 116.92 ? 408 GLU C CD  1 
ATOM   11262 O OE1 . GLU C 1 348 ? -100.007 -38.973 23.772  1.00 96.46  ? 408 GLU C OE1 1 
ATOM   11263 O OE2 . GLU C 1 348 ? -101.247 -40.289 22.469  1.00 106.73 ? 408 GLU C OE2 1 
ATOM   11264 N N   . GLU C 1 349 ? -103.311 -35.209 18.823  1.00 94.30  ? 409 GLU C N   1 
ATOM   11265 C CA  . GLU C 1 349 ? -103.958 -34.739 17.574  1.00 102.72 ? 409 GLU C CA  1 
ATOM   11266 C C   . GLU C 1 349 ? -103.016 -33.769 16.876  1.00 103.24 ? 409 GLU C C   1 
ATOM   11267 O O   . GLU C 1 349 ? -102.961 -33.796 15.641  1.00 113.50 ? 409 GLU C O   1 
ATOM   11268 C CB  . GLU C 1 349 ? -105.275 -33.997 17.814  1.00 119.96 ? 409 GLU C CB  1 
ATOM   11269 C CG  . GLU C 1 349 ? -106.075 -33.743 16.526  1.00 134.83 ? 409 GLU C CG  1 
ATOM   11270 C CD  . GLU C 1 349 ? -105.823 -32.504 15.655  1.00 143.09 ? 409 GLU C CD  1 
ATOM   11271 O OE1 . GLU C 1 349 ? -106.156 -32.557 14.449  1.00 134.43 ? 409 GLU C OE1 1 
ATOM   11272 O OE2 . GLU C 1 349 ? -105.293 -31.491 16.160  1.00 152.98 ? 409 GLU C OE2 1 
ATOM   11273 N N   . CYS C 1 350 ? -102.320 -32.912 17.627  1.00 95.17  ? 410 CYS C N   1 
ATOM   11274 C CA  . CYS C 1 350 ? -101.628 -31.682 17.136  1.00 79.30  ? 410 CYS C CA  1 
ATOM   11275 C C   . CYS C 1 350 ? -100.467 -31.989 16.170  1.00 77.22  ? 410 CYS C C   1 
ATOM   11276 O O   . CYS C 1 350 ? -100.021 -31.048 15.438  1.00 61.67  ? 410 CYS C O   1 
ATOM   11277 C CB  . CYS C 1 350 ? -101.142 -30.852 18.311  1.00 76.71  ? 410 CYS C CB  1 
ATOM   11278 S SG  . CYS C 1 350 ? -102.532 -29.932 18.991  1.00 71.50  ? 410 CYS C SG  1 
ATOM   11279 N N   . ARG C 1 351 ? -100.070 -33.267 16.114  1.00 62.45  ? 411 ARG C N   1 
ATOM   11280 C CA  . ARG C 1 351 ? -98.980  -33.778 15.267  1.00 63.54  ? 411 ARG C CA  1 
ATOM   11281 C C   . ARG C 1 351 ? -99.481  -34.231 13.885  1.00 64.40  ? 411 ARG C C   1 
ATOM   11282 O O   . ARG C 1 351 ? -98.639  -34.591 13.088  1.00 77.16  ? 411 ARG C O   1 
ATOM   11283 C CB  . ARG C 1 351 ? -98.325  -34.978 15.953  1.00 72.02  ? 411 ARG C CB  1 
ATOM   11284 C CG  . ARG C 1 351 ? -98.022  -34.826 17.432  1.00 74.81  ? 411 ARG C CG  1 
ATOM   11285 C CD  . ARG C 1 351 ? -97.228  -36.022 17.916  1.00 83.44  ? 411 ARG C CD  1 
ATOM   11286 N NE  . ARG C 1 351 ? -97.081  -35.983 19.361  1.00 79.97  ? 411 ARG C NE  1 
ATOM   11287 C CZ  . ARG C 1 351 ? -97.710  -36.776 20.221  1.00 80.67  ? 411 ARG C CZ  1 
ATOM   11288 N NH1 . ARG C 1 351 ? -98.535  -37.712 19.778  1.00 82.29  ? 411 ARG C NH1 1 
ATOM   11289 N NH2 . ARG C 1 351 ? -97.528  -36.619 21.524  1.00 82.76  ? 411 ARG C NH2 1 
ATOM   11290 N N   . LYS C 1 352 ? -100.777 -34.257 13.593  1.00 70.90  ? 412 LYS C N   1 
ATOM   11291 C CA  . LYS C 1 352 ? -101.292 -34.840 12.316  1.00 74.21  ? 412 LYS C CA  1 
ATOM   11292 C C   . LYS C 1 352 ? -100.711 -34.076 11.118  1.00 66.75  ? 412 LYS C C   1 
ATOM   11293 O O   . LYS C 1 352 ? -100.530 -34.734 10.114  1.00 73.47  ? 412 LYS C O   1 
ATOM   11294 C CB  . LYS C 1 352 ? -102.826 -34.928 12.301  1.00 85.78  ? 412 LYS C CB  1 
ATOM   11295 C CG  . LYS C 1 352 ? -103.590 -33.892 11.474  1.00 100.91 ? 412 LYS C CG  1 
ATOM   11296 C CD  . LYS C 1 352 ? -105.105 -34.155 11.425  1.00 104.65 ? 412 LYS C CD  1 
ATOM   11297 C CE  . LYS C 1 352 ? -105.805 -33.520 10.232  1.00 106.58 ? 412 LYS C CE  1 
ATOM   11298 N NZ  . LYS C 1 352 ? -107.183 -34.040 10.061  1.00 101.41 ? 412 LYS C NZ  1 
ATOM   11299 N N   . LYS C 1 353 ? -100.403 -32.774 11.227  1.00 65.61  ? 413 LYS C N   1 
ATOM   11300 C CA  . LYS C 1 353 ? -99.876  -31.941 10.102  1.00 68.12  ? 413 LYS C CA  1 
ATOM   11301 C C   . LYS C 1 353 ? -98.349  -31.724 10.165  1.00 69.78  ? 413 LYS C C   1 
ATOM   11302 O O   . LYS C 1 353 ? -97.833  -30.894 9.385   1.00 67.68  ? 413 LYS C O   1 
ATOM   11303 C CB  . LYS C 1 353 ? -100.683 -30.651 10.044  1.00 70.25  ? 413 LYS C CB  1 
ATOM   11304 C CG  . LYS C 1 353 ? -102.086 -30.906 9.521   1.00 74.30  ? 413 LYS C CG  1 
ATOM   11305 C CD  . LYS C 1 353 ? -102.961 -29.690 9.592   1.00 86.45  ? 413 LYS C CD  1 
ATOM   11306 C CE  . LYS C 1 353 ? -102.613 -28.628 8.571   1.00 90.18  ? 413 LYS C CE  1 
ATOM   11307 N NZ  . LYS C 1 353 ? -102.857 -29.091 7.185   1.00 105.09 ? 413 LYS C NZ  1 
ATOM   11308 N N   . VAL C 1 354 ? -97.641  -32.541 10.945  1.00 73.96  ? 414 VAL C N   1 
ATOM   11309 C CA  . VAL C 1 354 ? -96.159  -32.513 11.129  1.00 65.66  ? 414 VAL C CA  1 
ATOM   11310 C C   . VAL C 1 354 ? -95.592  -33.874 10.705  1.00 70.30  ? 414 VAL C C   1 
ATOM   11311 O O   . VAL C 1 354 ? -95.951  -34.902 11.350  1.00 60.92  ? 414 VAL C O   1 
ATOM   11312 C CB  . VAL C 1 354 ? -95.819  -32.202 12.593  1.00 59.23  ? 414 VAL C CB  1 
ATOM   11313 C CG1 . VAL C 1 354 ? -94.328  -32.198 12.847  1.00 62.24  ? 414 VAL C CG1 1 
ATOM   11314 C CG2 . VAL C 1 354 ? -96.438  -30.895 13.036  1.00 60.76  ? 414 VAL C CG2 1 
ATOM   11315 N N   . TRP C 1 355 ? -94.731  -33.860 9.683   1.00 70.06  ? 415 TRP C N   1 
ATOM   11316 C CA  . TRP C 1 355 ? -94.148  -35.057 9.020   1.00 73.55  ? 415 TRP C CA  1 
ATOM   11317 C C   . TRP C 1 355 ? -92.626  -34.967 9.021   1.00 68.80  ? 415 TRP C C   1 
ATOM   11318 O O   . TRP C 1 355 ? -92.125  -33.917 8.572   1.00 68.59  ? 415 TRP C O   1 
ATOM   11319 C CB  . TRP C 1 355 ? -94.637  -35.148 7.576   1.00 76.75  ? 415 TRP C CB  1 
ATOM   11320 C CG  . TRP C 1 355 ? -96.119  -35.131 7.416   1.00 72.58  ? 415 TRP C CG  1 
ATOM   11321 C CD1 . TRP C 1 355 ? -96.924  -34.034 7.344   1.00 73.06  ? 415 TRP C CD1 1 
ATOM   11322 C CD2 . TRP C 1 355 ? -96.967  -36.277 7.263   1.00 73.46  ? 415 TRP C CD2 1 
ATOM   11323 N NE1 . TRP C 1 355 ? -98.224  -34.419 7.166   1.00 79.52  ? 415 TRP C NE1 1 
ATOM   11324 C CE2 . TRP C 1 355 ? -98.279  -35.788 7.112   1.00 78.14  ? 415 TRP C CE2 1 
ATOM   11325 C CE3 . TRP C 1 355 ? -96.748  -37.659 7.250   1.00 71.93  ? 415 TRP C CE3 1 
ATOM   11326 C CZ2 . TRP C 1 355 ? -99.365  -36.639 6.938   1.00 83.37  ? 415 TRP C CZ2 1 
ATOM   11327 C CZ3 . TRP C 1 355 ? -97.824  -38.498 7.085   1.00 75.58  ? 415 TRP C CZ3 1 
ATOM   11328 C CH2 . TRP C 1 355 ? -99.115  -37.991 6.934   1.00 78.80  ? 415 TRP C CH2 1 
ATOM   11329 N N   . LEU C 1 356 ? -91.936  -36.040 9.423   1.00 69.37  ? 416 LEU C N   1 
ATOM   11330 C CA  . LEU C 1 356 ? -90.453  -36.104 9.400   1.00 65.70  ? 416 LEU C CA  1 
ATOM   11331 C C   . LEU C 1 356 ? -89.987  -37.185 8.428   1.00 63.92  ? 416 LEU C C   1 
ATOM   11332 O O   . LEU C 1 356 ? -90.672  -38.258 8.360   1.00 81.48  ? 416 LEU C O   1 
ATOM   11333 C CB  . LEU C 1 356 ? -89.935  -36.358 10.814  1.00 68.20  ? 416 LEU C CB  1 
ATOM   11334 C CG  . LEU C 1 356 ? -90.157  -35.191 11.775  1.00 71.67  ? 416 LEU C CG  1 
ATOM   11335 C CD1 . LEU C 1 356 ? -91.463  -35.379 12.518  1.00 73.01  ? 416 LEU C CD1 1 
ATOM   11336 C CD2 . LEU C 1 356 ? -88.995  -35.035 12.741  1.00 80.08  ? 416 LEU C CD2 1 
ATOM   11337 N N   . VAL C 1 357 ? -88.895  -36.894 7.706   1.00 54.06  ? 417 VAL C N   1 
ATOM   11338 C CA  . VAL C 1 357 ? -88.217  -37.810 6.747   1.00 56.24  ? 417 VAL C CA  1 
ATOM   11339 C C   . VAL C 1 357 ? -86.794  -38.085 7.244   1.00 63.06  ? 417 VAL C C   1 
ATOM   11340 O O   . VAL C 1 357 ? -85.963  -37.131 7.355   1.00 48.66  ? 417 VAL C O   1 
ATOM   11341 C CB  . VAL C 1 357 ? -88.196  -37.222 5.332   1.00 58.12  ? 417 VAL C CB  1 
ATOM   11342 C CG1 . VAL C 1 357 ? -87.499  -38.151 4.343   1.00 56.23  ? 417 VAL C CG1 1 
ATOM   11343 C CG2 . VAL C 1 357 ? -89.605  -36.850 4.857   1.00 63.02  ? 417 VAL C CG2 1 
ATOM   11344 N N   . ASP C 1 358 ? -86.531  -39.369 7.501   1.00 67.05  ? 418 ASP C N   1 
ATOM   11345 C CA  . ASP C 1 358 ? -85.229  -39.891 7.967   1.00 72.52  ? 418 ASP C CA  1 
ATOM   11346 C C   . ASP C 1 358 ? -84.478  -40.500 6.778   1.00 74.78  ? 418 ASP C C   1 
ATOM   11347 O O   . ASP C 1 358 ? -84.932  -40.323 5.614   1.00 73.22  ? 418 ASP C O   1 
ATOM   11348 C CB  . ASP C 1 358 ? -85.462  -40.904 9.084   1.00 80.59  ? 418 ASP C CB  1 
ATOM   11349 C CG  . ASP C 1 358 ? -86.143  -42.181 8.617   1.00 84.37  ? 418 ASP C CG  1 
ATOM   11350 O OD1 . ASP C 1 358 ? -86.037  -42.484 7.419   1.00 78.68  ? 418 ASP C OD1 1 
ATOM   11351 O OD2 . ASP C 1 358 ? -86.814  -42.849 9.444   1.00 96.38  ? 418 ASP C OD2 1 
ATOM   11352 N N   . SER C 1 359 ? -83.374  -41.190 7.080   1.00 87.95  ? 419 SER C N   1 
ATOM   11353 C CA  . SER C 1 359 ? -82.492  -41.921 6.130   1.00 90.97  ? 419 SER C CA  1 
ATOM   11354 C C   . SER C 1 359 ? -83.308  -42.881 5.246   1.00 82.31  ? 419 SER C C   1 
ATOM   11355 O O   . SER C 1 359 ? -83.017  -42.967 4.048   1.00 71.70  ? 419 SER C O   1 
ATOM   11356 C CB  . SER C 1 359 ? -81.381  -42.644 6.890   1.00 99.04  ? 419 SER C CB  1 
ATOM   11357 O OG  . SER C 1 359 ? -81.651  -42.718 8.296   1.00 93.21  ? 419 SER C OG  1 
ATOM   11358 N N   . LYS C 1 360 ? -84.301  -43.579 5.817   1.00 83.84  ? 420 LYS C N   1 
ATOM   11359 C CA  . LYS C 1 360 ? -85.074  -44.645 5.119   1.00 87.05  ? 420 LYS C CA  1 
ATOM   11360 C C   . LYS C 1 360 ? -86.308  -44.049 4.417   1.00 80.47  ? 420 LYS C C   1 
ATOM   11361 O O   . LYS C 1 360 ? -87.024  -44.822 3.745   1.00 72.38  ? 420 LYS C O   1 
ATOM   11362 C CB  . LYS C 1 360 ? -85.451  -45.738 6.124   1.00 94.34  ? 420 LYS C CB  1 
ATOM   11363 C CG  . LYS C 1 360 ? -84.265  -46.478 6.739   1.00 96.78  ? 420 LYS C CG  1 
ATOM   11364 C CD  . LYS C 1 360 ? -84.614  -47.302 7.958   1.00 102.56 ? 420 LYS C CD  1 
ATOM   11365 C CE  . LYS C 1 360 ? -85.539  -48.464 7.649   1.00 107.41 ? 420 LYS C CE  1 
ATOM   11366 N NZ  . LYS C 1 360 ? -86.192  -48.963 8.881   1.00 108.23 ? 420 LYS C NZ  1 
ATOM   11367 N N   . GLY C 1 361 ? -86.568  -42.744 4.574   1.00 76.02  ? 421 GLY C N   1 
ATOM   11368 C CA  . GLY C 1 361 ? -87.656  -42.003 3.895   1.00 66.53  ? 421 GLY C CA  1 
ATOM   11369 C C   . GLY C 1 361 ? -88.669  -41.392 4.869   1.00 68.97  ? 421 GLY C C   1 
ATOM   11370 O O   . GLY C 1 361 ? -88.305  -41.115 6.024   1.00 75.16  ? 421 GLY C O   1 
ATOM   11371 N N   . LEU C 1 362 ? -89.908  -41.173 4.423   1.00 65.76  ? 422 LEU C N   1 
ATOM   11372 C CA  . LEU C 1 362 ? -91.011  -40.623 5.259   1.00 69.41  ? 422 LEU C CA  1 
ATOM   11373 C C   . LEU C 1 362 ? -91.342  -41.609 6.377   1.00 71.84  ? 422 LEU C C   1 
ATOM   11374 O O   . LEU C 1 362 ? -91.549  -42.805 6.067   1.00 76.49  ? 422 LEU C O   1 
ATOM   11375 C CB  . LEU C 1 362 ? -92.251  -40.346 4.397   1.00 74.79  ? 422 LEU C CB  1 
ATOM   11376 C CG  . LEU C 1 362 ? -93.436  -39.698 5.125   1.00 68.11  ? 422 LEU C CG  1 
ATOM   11377 C CD1 . LEU C 1 362 ? -93.060  -38.327 5.665   1.00 69.30  ? 422 LEU C CD1 1 
ATOM   11378 C CD2 . LEU C 1 362 ? -94.662  -39.598 4.231   1.00 59.34  ? 422 LEU C CD2 1 
ATOM   11379 N N   . ILE C 1 363 ? -91.373  -41.121 7.616   1.00 83.87  ? 423 ILE C N   1 
ATOM   11380 C CA  . ILE C 1 363 ? -91.815  -41.914 8.800   1.00 85.16  ? 423 ILE C CA  1 
ATOM   11381 C C   . ILE C 1 363 ? -93.334  -42.105 8.695   1.00 89.75  ? 423 ILE C C   1 
ATOM   11382 O O   . ILE C 1 363 ? -94.087  -41.088 8.743   1.00 85.55  ? 423 ILE C O   1 
ATOM   11383 C CB  . ILE C 1 363 ? -91.361  -41.281 10.137  1.00 73.77  ? 423 ILE C CB  1 
ATOM   11384 C CG1 . ILE C 1 363 ? -89.836  -41.263 10.251  1.00 66.33  ? 423 ILE C CG1 1 
ATOM   11385 C CG2 . ILE C 1 363 ? -91.959  -42.030 11.329  1.00 67.83  ? 423 ILE C CG2 1 
ATOM   11386 C CD1 . ILE C 1 363 ? -89.196  -39.913 10.140  1.00 69.19  ? 423 ILE C CD1 1 
ATOM   11387 N N   . VAL C 1 364 ? -93.742  -43.368 8.526   1.00 99.98  ? 424 VAL C N   1 
ATOM   11388 C CA  . VAL C 1 364 ? -95.157  -43.780 8.303   1.00 95.01  ? 424 VAL C CA  1 
ATOM   11389 C C   . VAL C 1 364 ? -95.505  -44.918 9.267   1.00 89.52  ? 424 VAL C C   1 
ATOM   11390 O O   . VAL C 1 364 ? -94.562  -45.588 9.720   1.00 74.01  ? 424 VAL C O   1 
ATOM   11391 C CB  . VAL C 1 364 ? -95.386  -44.188 6.841   1.00 99.72  ? 424 VAL C CB  1 
ATOM   11392 C CG1 . VAL C 1 364 ? -96.864  -44.232 6.565   1.00 110.57 ? 424 VAL C CG1 1 
ATOM   11393 C CG2 . VAL C 1 364 ? -94.685  -43.277 5.840   1.00 111.20 ? 424 VAL C CG2 1 
ATOM   11394 N N   . ASP C 1 365 ? -96.793  -45.078 9.606   1.00 96.27  ? 425 ASP C N   1 
ATOM   11395 C CA  . ASP C 1 365 ? -97.284  -46.044 10.631  1.00 107.57 ? 425 ASP C CA  1 
ATOM   11396 C C   . ASP C 1 365 ? -97.003  -47.487 10.196  1.00 99.59  ? 425 ASP C C   1 
ATOM   11397 O O   . ASP C 1 365 ? -96.658  -48.313 11.072  1.00 94.88  ? 425 ASP C O   1 
ATOM   11398 C CB  . ASP C 1 365 ? -98.736  -45.740 11.021  1.00 119.60 ? 425 ASP C CB  1 
ATOM   11399 C CG  . ASP C 1 365 ? -99.654  -46.954 11.113  1.00 138.93 ? 425 ASP C CG  1 
ATOM   11400 O OD1 . ASP C 1 365 ? -99.582  -47.811 10.215  1.00 139.38 ? 425 ASP C OD1 1 
ATOM   11401 O OD2 . ASP C 1 365 ? -100.418 -47.051 12.107  1.00 161.98 ? 425 ASP C OD2 1 
ATOM   11402 N N   . SER C 1 366 ? -97.093  -47.776 8.895   1.00 89.57  ? 426 SER C N   1 
ATOM   11403 C CA  . SER C 1 366 ? -96.790  -49.102 8.301   1.00 88.18  ? 426 SER C CA  1 
ATOM   11404 C C   . SER C 1 366 ? -95.376  -49.558 8.684   1.00 88.61  ? 426 SER C C   1 
ATOM   11405 O O   . SER C 1 366 ? -95.113  -50.764 8.577   1.00 103.75 ? 426 SER C O   1 
ATOM   11406 C CB  . SER C 1 366 ? -96.976  -49.072 6.814   1.00 94.94  ? 426 SER C CB  1 
ATOM   11407 O OG  . SER C 1 366 ? -96.078  -48.159 6.214   1.00 104.49 ? 426 SER C OG  1 
ATOM   11408 N N   . ARG C 1 367 ? -94.515  -48.647 9.133   1.00 85.21  ? 427 ARG C N   1 
ATOM   11409 C CA  . ARG C 1 367 ? -93.099  -48.928 9.470   1.00 97.07  ? 427 ARG C CA  1 
ATOM   11410 C C   . ARG C 1 367 ? -92.886  -49.068 10.989  1.00 109.88 ? 427 ARG C C   1 
ATOM   11411 O O   . ARG C 1 367 ? -91.729  -49.379 11.365  1.00 121.36 ? 427 ARG C O   1 
ATOM   11412 C CB  . ARG C 1 367 ? -92.199  -47.802 8.971   1.00 101.60 ? 427 ARG C CB  1 
ATOM   11413 C CG  . ARG C 1 367 ? -92.258  -47.491 7.483   1.00 102.94 ? 427 ARG C CG  1 
ATOM   11414 C CD  . ARG C 1 367 ? -91.364  -46.328 7.115   1.00 96.74  ? 427 ARG C CD  1 
ATOM   11415 N NE  . ARG C 1 367 ? -90.215  -46.148 8.002   1.00 96.34  ? 427 ARG C NE  1 
ATOM   11416 C CZ  . ARG C 1 367 ? -89.340  -45.152 7.925   1.00 93.93  ? 427 ARG C CZ  1 
ATOM   11417 N NH1 . ARG C 1 367 ? -89.471  -44.234 6.985   1.00 81.15  ? 427 ARG C NH1 1 
ATOM   11418 N NH2 . ARG C 1 367 ? -88.338  -45.064 8.786   1.00 93.99  ? 427 ARG C NH2 1 
ATOM   11419 N N   . LYS C 1 368 ? -93.921  -48.869 11.822  1.00 116.93 ? 428 LYS C N   1 
ATOM   11420 C CA  . LYS C 1 368 ? -93.743  -48.728 13.302  1.00 121.99 ? 428 LYS C CA  1 
ATOM   11421 C C   . LYS C 1 368 ? -93.540  -50.099 13.975  1.00 113.31 ? 428 LYS C C   1 
ATOM   11422 O O   . LYS C 1 368 ? -93.046  -50.109 15.116  1.00 95.54  ? 428 LYS C O   1 
ATOM   11423 C CB  . LYS C 1 368 ? -94.809  -47.826 13.938  1.00 121.68 ? 428 LYS C CB  1 
ATOM   11424 C CG  . LYS C 1 368 ? -96.098  -48.436 14.471  1.00 123.89 ? 428 LYS C CG  1 
ATOM   11425 C CD  . LYS C 1 368 ? -96.826  -47.435 15.371  1.00 120.51 ? 428 LYS C CD  1 
ATOM   11426 C CE  . LYS C 1 368 ? -98.211  -47.042 14.892  1.00 112.44 ? 428 LYS C CE  1 
ATOM   11427 N NZ  . LYS C 1 368 ? -98.541  -45.629 15.214  1.00 103.25 ? 428 LYS C NZ  1 
ATOM   11428 N N   . GLY C 1 369 ? -93.834  -51.194 13.268  1.00 115.05 ? 429 GLY C N   1 
ATOM   11429 C CA  . GLY C 1 369 ? -93.570  -52.584 13.693  1.00 114.80 ? 429 GLY C CA  1 
ATOM   11430 C C   . GLY C 1 369 ? -92.081  -52.920 13.761  1.00 123.89 ? 429 GLY C C   1 
ATOM   11431 O O   . GLY C 1 369 ? -91.775  -54.113 13.984  1.00 148.89 ? 429 GLY C O   1 
ATOM   11432 N N   . SER C 1 370 ? -91.188  -51.935 13.564  1.00 116.51 ? 430 SER C N   1 
ATOM   11433 C CA  . SER C 1 370 ? -89.731  -52.002 13.892  1.00 111.52 ? 430 SER C CA  1 
ATOM   11434 C C   . SER C 1 370 ? -89.094  -50.605 13.791  1.00 100.41 ? 430 SER C C   1 
ATOM   11435 O O   . SER C 1 370 ? -88.107  -50.424 13.083  1.00 88.55  ? 430 SER C O   1 
ATOM   11436 C CB  . SER C 1 370 ? -89.005  -53.042 13.049  1.00 109.97 ? 430 SER C CB  1 
ATOM   11437 O OG  . SER C 1 370 ? -89.395  -52.965 11.691  1.00 91.04  ? 430 SER C OG  1 
ATOM   11438 N N   . LEU C 1 371 ? -89.654  -49.647 14.522  1.00 102.68 ? 431 LEU C N   1 
ATOM   11439 C CA  . LEU C 1 371 ? -89.217  -48.228 14.569  1.00 94.16  ? 431 LEU C CA  1 
ATOM   11440 C C   . LEU C 1 371 ? -88.497  -47.982 15.894  1.00 106.16 ? 431 LEU C C   1 
ATOM   11441 O O   . LEU C 1 371 ? -88.638  -48.806 16.825  1.00 150.90 ? 431 LEU C O   1 
ATOM   11442 C CB  . LEU C 1 371 ? -90.439  -47.312 14.464  1.00 86.80  ? 431 LEU C CB  1 
ATOM   11443 C CG  . LEU C 1 371 ? -90.532  -46.459 13.200  1.00 91.26  ? 431 LEU C CG  1 
ATOM   11444 C CD1 . LEU C 1 371 ? -91.780  -45.581 13.196  1.00 82.34  ? 431 LEU C CD1 1 
ATOM   11445 C CD2 . LEU C 1 371 ? -89.280  -45.612 13.032  1.00 100.37 ? 431 LEU C CD2 1 
ATOM   11446 N N   . GLN C 1 372 ? -87.765  -46.873 15.987  1.00 95.21  ? 432 GLN C N   1 
ATOM   11447 C CA  . GLN C 1 372 ? -87.165  -46.364 17.247  1.00 100.79 ? 432 GLN C CA  1 
ATOM   11448 C C   . GLN C 1 372 ? -88.315  -45.723 18.039  1.00 109.92 ? 432 GLN C C   1 
ATOM   11449 O O   . GLN C 1 372 ? -89.260  -45.220 17.435  1.00 104.76 ? 432 GLN C O   1 
ATOM   11450 C CB  . GLN C 1 372 ? -85.987  -45.438 16.895  1.00 106.40 ? 432 GLN C CB  1 
ATOM   11451 C CG  . GLN C 1 372 ? -84.788  -46.130 16.216  1.00 96.03  ? 432 GLN C CG  1 
ATOM   11452 C CD  . GLN C 1 372 ? -84.718  -46.080 14.691  1.00 85.08  ? 432 GLN C CD  1 
ATOM   11453 O OE1 . GLN C 1 372 ? -85.709  -46.120 13.964  1.00 67.36  ? 432 GLN C OE1 1 
ATOM   11454 N NE2 . GLN C 1 372 ? -83.508  -46.003 14.150  1.00 66.60  ? 432 GLN C NE2 1 
ATOM   11455 N N   . PRO C 1 373 ? -88.320  -45.725 19.394  1.00 125.32 ? 433 PRO C N   1 
ATOM   11456 C CA  . PRO C 1 373 ? -89.483  -45.271 20.169  1.00 110.18 ? 433 PRO C CA  1 
ATOM   11457 C C   . PRO C 1 373 ? -89.931  -43.818 19.922  1.00 90.42  ? 433 PRO C C   1 
ATOM   11458 O O   . PRO C 1 373 ? -91.103  -43.626 19.741  1.00 77.02  ? 433 PRO C O   1 
ATOM   11459 C CB  . PRO C 1 373 ? -89.045  -45.423 21.638  1.00 121.35 ? 433 PRO C CB  1 
ATOM   11460 C CG  . PRO C 1 373 ? -87.878  -46.387 21.599  1.00 131.37 ? 433 PRO C CG  1 
ATOM   11461 C CD  . PRO C 1 373 ? -87.205  -46.126 20.267  1.00 139.00 ? 433 PRO C CD  1 
ATOM   11462 N N   . PHE C 1 374 ? -88.998  -42.860 19.884  1.00 82.16  ? 434 PHE C N   1 
ATOM   11463 C CA  . PHE C 1 374 ? -89.275  -41.399 19.823  1.00 85.89  ? 434 PHE C CA  1 
ATOM   11464 C C   . PHE C 1 374 ? -89.725  -40.959 18.433  1.00 89.51  ? 434 PHE C C   1 
ATOM   11465 O O   . PHE C 1 374 ? -89.842  -39.733 18.247  1.00 86.94  ? 434 PHE C O   1 
ATOM   11466 C CB  . PHE C 1 374 ? -88.039  -40.566 20.190  1.00 92.46  ? 434 PHE C CB  1 
ATOM   11467 C CG  . PHE C 1 374 ? -86.861  -40.687 19.253  1.00 104.66 ? 434 PHE C CG  1 
ATOM   11468 C CD1 . PHE C 1 374 ? -86.806  -39.991 18.053  1.00 100.60 ? 434 PHE C CD1 1 
ATOM   11469 C CD2 . PHE C 1 374 ? -85.765  -41.465 19.608  1.00 119.37 ? 434 PHE C CD2 1 
ATOM   11470 C CE1 . PHE C 1 374 ? -85.717  -40.124 17.204  1.00 103.51 ? 434 PHE C CE1 1 
ATOM   11471 C CE2 . PHE C 1 374 ? -84.678  -41.597 18.759  1.00 115.73 ? 434 PHE C CE2 1 
ATOM   11472 C CZ  . PHE C 1 374 ? -84.659  -40.928 17.556  1.00 113.83 ? 434 PHE C CZ  1 
ATOM   11473 N N   . LYS C 1 375 ? -89.931  -41.907 17.509  1.00 92.52  ? 435 LYS C N   1 
ATOM   11474 C CA  . LYS C 1 375 ? -90.408  -41.666 16.118  1.00 84.18  ? 435 LYS C CA  1 
ATOM   11475 C C   . LYS C 1 375 ? -91.889  -42.040 15.983  1.00 88.46  ? 435 LYS C C   1 
ATOM   11476 O O   . LYS C 1 375 ? -92.562  -41.400 15.152  1.00 94.09  ? 435 LYS C O   1 
ATOM   11477 C CB  . LYS C 1 375 ? -89.565  -42.470 15.125  1.00 85.45  ? 435 LYS C CB  1 
ATOM   11478 C CG  . LYS C 1 375 ? -88.116  -42.020 14.996  1.00 96.35  ? 435 LYS C CG  1 
ATOM   11479 C CD  . LYS C 1 375 ? -87.293  -42.782 13.964  1.00 97.27  ? 435 LYS C CD  1 
ATOM   11480 C CE  . LYS C 1 375 ? -86.059  -42.028 13.497  1.00 93.18  ? 435 LYS C CE  1 
ATOM   11481 N NZ  . LYS C 1 375 ? -84.884  -42.918 13.293  1.00 110.67 ? 435 LYS C NZ  1 
ATOM   11482 N N   . LYS C 1 376 ? -92.374  -43.006 16.783  1.00 95.54  ? 436 LYS C N   1 
ATOM   11483 C CA  . LYS C 1 376 ? -93.755  -43.573 16.693  1.00 89.84  ? 436 LYS C CA  1 
ATOM   11484 C C   . LYS C 1 376 ? -94.805  -42.464 16.715  1.00 74.99  ? 436 LYS C C   1 
ATOM   11485 O O   . LYS C 1 376 ? -95.759  -42.504 15.957  1.00 76.25  ? 436 LYS C O   1 
ATOM   11486 C CB  . LYS C 1 376 ? -93.985  -44.598 17.814  1.00 104.60 ? 436 LYS C CB  1 
ATOM   11487 C CG  . LYS C 1 376 ? -93.492  -46.007 17.512  1.00 121.68 ? 436 LYS C CG  1 
ATOM   11488 C CD  . LYS C 1 376 ? -92.831  -46.712 18.702  1.00 131.54 ? 436 LYS C CD  1 
ATOM   11489 C CE  . LYS C 1 376 ? -92.008  -47.908 18.282  1.00 132.75 ? 436 LYS C CE  1 
ATOM   11490 N NZ  . LYS C 1 376 ? -90.797  -48.102 19.127  1.00 135.05 ? 436 LYS C NZ  1 
ATOM   11491 N N   . PRO C 1 377 ? -94.688  -41.433 17.583  1.00 76.58  ? 437 PRO C N   1 
ATOM   11492 C CA  . PRO C 1 377 ? -95.634  -40.316 17.580  1.00 80.39  ? 437 PRO C CA  1 
ATOM   11493 C C   . PRO C 1 377 ? -95.719  -39.496 16.284  1.00 76.02  ? 437 PRO C C   1 
ATOM   11494 O O   . PRO C 1 377 ? -96.593  -38.674 16.199  1.00 80.90  ? 437 PRO C O   1 
ATOM   11495 C CB  . PRO C 1 377 ? -95.091  -39.392 18.686  1.00 82.39  ? 437 PRO C CB  1 
ATOM   11496 C CG  . PRO C 1 377 ? -94.370  -40.322 19.624  1.00 76.55  ? 437 PRO C CG  1 
ATOM   11497 C CD  . PRO C 1 377 ? -93.704  -41.295 18.669  1.00 82.10  ? 437 PRO C CD  1 
ATOM   11498 N N   . TRP C 1 378 ? -94.818  -39.713 15.334  1.00 72.98  ? 438 TRP C N   1 
ATOM   11499 C CA  . TRP C 1 378 ? -94.804  -38.966 14.053  1.00 76.69  ? 438 TRP C CA  1 
ATOM   11500 C C   . TRP C 1 378 ? -95.176  -39.875 12.880  1.00 81.74  ? 438 TRP C C   1 
ATOM   11501 O O   . TRP C 1 378 ? -95.360  -39.337 11.742  1.00 79.23  ? 438 TRP C O   1 
ATOM   11502 C CB  . TRP C 1 378 ? -93.450  -38.285 13.890  1.00 72.32  ? 438 TRP C CB  1 
ATOM   11503 C CG  . TRP C 1 378 ? -93.088  -37.526 15.125  1.00 76.68  ? 438 TRP C CG  1 
ATOM   11504 C CD1 . TRP C 1 378 ? -92.226  -37.933 16.096  1.00 72.61  ? 438 TRP C CD1 1 
ATOM   11505 C CD2 . TRP C 1 378 ? -93.622  -36.258 15.561  1.00 69.19  ? 438 TRP C CD2 1 
ATOM   11506 N NE1 . TRP C 1 378 ? -92.158  -36.991 17.084  1.00 65.68  ? 438 TRP C NE1 1 
ATOM   11507 C CE2 . TRP C 1 378 ? -93.006  -35.961 16.793  1.00 63.96  ? 438 TRP C CE2 1 
ATOM   11508 C CE3 . TRP C 1 378 ? -94.550  -35.348 15.038  1.00 66.41  ? 438 TRP C CE3 1 
ATOM   11509 C CZ2 . TRP C 1 378 ? -93.272  -34.794 17.507  1.00 62.91  ? 438 TRP C CZ2 1 
ATOM   11510 C CZ3 . TRP C 1 378 ? -94.820  -34.200 15.749  1.00 66.96  ? 438 TRP C CZ3 1 
ATOM   11511 C CH2 . TRP C 1 378 ? -94.193  -33.932 16.969  1.00 63.47  ? 438 TRP C CH2 1 
ATOM   11512 N N   . ALA C 1 379 ? -95.366  -41.166 13.176  1.00 82.92  ? 439 ALA C N   1 
ATOM   11513 C CA  . ALA C 1 379 ? -95.757  -42.235 12.232  1.00 85.40  ? 439 ALA C CA  1 
ATOM   11514 C C   . ALA C 1 379 ? -97.245  -42.123 11.871  1.00 79.02  ? 439 ALA C C   1 
ATOM   11515 O O   . ALA C 1 379 ? -98.004  -43.011 12.228  1.00 91.35  ? 439 ALA C O   1 
ATOM   11516 C CB  . ALA C 1 379 ? -95.411  -43.577 12.841  1.00 87.38  ? 439 ALA C CB  1 
ATOM   11517 N N   . HIS C 1 380 ? -97.636  -41.076 11.156  1.00 83.57  ? 440 HIS C N   1 
ATOM   11518 C CA  . HIS C 1 380 ? -99.022  -40.870 10.663  1.00 89.07  ? 440 HIS C CA  1 
ATOM   11519 C C   . HIS C 1 380 ? -99.288  -41.890 9.541   1.00 95.11  ? 440 HIS C C   1 
ATOM   11520 O O   . HIS C 1 380 ? -98.454  -42.811 9.364   1.00 78.18  ? 440 HIS C O   1 
ATOM   11521 C CB  . HIS C 1 380 ? -99.230  -39.406 10.244  1.00 87.82  ? 440 HIS C CB  1 
ATOM   11522 C CG  . HIS C 1 380 ? -98.642  -38.428 11.201  1.00 79.60  ? 440 HIS C CG  1 
ATOM   11523 N ND1 . HIS C 1 380 ? -98.868  -38.529 12.543  1.00 77.62  ? 440 HIS C ND1 1 
ATOM   11524 C CD2 . HIS C 1 380 ? -97.816  -37.376 11.025  1.00 75.66  ? 440 HIS C CD2 1 
ATOM   11525 C CE1 . HIS C 1 380 ? -98.219  -37.563 13.153  1.00 78.38  ? 440 HIS C CE1 1 
ATOM   11526 N NE2 . HIS C 1 380 ? -97.551  -36.849 12.237  1.00 71.78  ? 440 HIS C NE2 1 
ATOM   11527 N N   . GLU C 1 381 ? -100.430 -41.762 8.848   1.00 114.83 ? 441 GLU C N   1 
ATOM   11528 C CA  . GLU C 1 381 ? -100.854 -42.729 7.799   1.00 124.72 ? 441 GLU C CA  1 
ATOM   11529 C C   . GLU C 1 381 ? -100.711 -42.105 6.407   1.00 104.10 ? 441 GLU C C   1 
ATOM   11530 O O   . GLU C 1 381 ? -101.285 -41.047 6.142   1.00 110.98 ? 441 GLU C O   1 
ATOM   11531 C CB  . GLU C 1 381 ? -102.183 -43.376 8.195   1.00 146.74 ? 441 GLU C CB  1 
ATOM   11532 C CG  . GLU C 1 381 ? -101.841 -44.506 9.147   1.00 179.99 ? 441 GLU C CG  1 
ATOM   11533 C CD  . GLU C 1 381 ? -100.885 -45.514 8.505   1.00 217.19 ? 441 GLU C CD  1 
ATOM   11534 O OE1 . GLU C 1 381 ? -101.357 -46.312 7.704   1.00 260.88 ? 441 GLU C OE1 1 
ATOM   11535 O OE2 . GLU C 1 381 ? -99.650  -45.410 8.699   1.00 221.02 ? 441 GLU C OE2 1 
ATOM   11536 N N   . HIS C 1 382 ? -99.927  -42.778 5.562   1.00 81.70  ? 442 HIS C N   1 
ATOM   11537 C CA  . HIS C 1 382 ? -99.533  -42.366 4.186   1.00 78.06  ? 442 HIS C CA  1 
ATOM   11538 C C   . HIS C 1 382 ? -98.893  -43.566 3.477   1.00 76.75  ? 442 HIS C C   1 
ATOM   11539 O O   . HIS C 1 382 ? -98.560  -44.528 4.188   1.00 79.17  ? 442 HIS C O   1 
ATOM   11540 C CB  . HIS C 1 382 ? -98.528  -41.221 4.297   1.00 72.71  ? 442 HIS C CB  1 
ATOM   11541 C CG  . HIS C 1 382 ? -98.511  -40.325 3.117   1.00 65.49  ? 442 HIS C CG  1 
ATOM   11542 N ND1 . HIS C 1 382 ? -99.210  -39.149 3.106   1.00 71.83  ? 442 HIS C ND1 1 
ATOM   11543 C CD2 . HIS C 1 382 ? -97.914  -40.425 1.914   1.00 73.62  ? 442 HIS C CD2 1 
ATOM   11544 C CE1 . HIS C 1 382 ? -99.037  -38.525 1.955   1.00 74.13  ? 442 HIS C CE1 1 
ATOM   11545 N NE2 . HIS C 1 382 ? -98.253  -39.300 1.203   1.00 87.90  ? 442 HIS C NE2 1 
ATOM   11546 N N   . GLU C 1 383 ? -98.639  -43.522 2.172   1.00 80.67  ? 443 GLU C N   1 
ATOM   11547 C CA  . GLU C 1 383 ? -97.839  -44.603 1.540   1.00 100.97 ? 443 GLU C CA  1 
ATOM   11548 C C   . GLU C 1 383 ? -96.375  -44.306 1.827   1.00 99.28  ? 443 GLU C C   1 
ATOM   11549 O O   . GLU C 1 383 ? -96.031  -43.132 1.949   1.00 87.92  ? 443 GLU C O   1 
ATOM   11550 C CB  . GLU C 1 383 ? -98.200  -44.764 0.062   1.00 113.76 ? 443 GLU C CB  1 
ATOM   11551 C CG  . GLU C 1 383 ? -99.598  -45.363 -0.144  1.00 132.23 ? 443 GLU C CG  1 
ATOM   11552 C CD  . GLU C 1 383 ? -99.780  -46.885 -0.027  1.00 131.93 ? 443 GLU C CD  1 
ATOM   11553 O OE1 . GLU C 1 383 ? -98.988  -47.640 -0.655  1.00 123.64 ? 443 GLU C OE1 1 
ATOM   11554 O OE2 . GLU C 1 383 ? -100.733 -47.326 0.686   1.00 126.15 ? 443 GLU C OE2 1 
ATOM   11555 N N   . PRO C 1 384 ? -95.499  -45.334 2.037   1.00 97.73  ? 444 PRO C N   1 
ATOM   11556 C CA  . PRO C 1 384 ? -94.056  -45.104 2.180   1.00 104.79 ? 444 PRO C CA  1 
ATOM   11557 C C   . PRO C 1 384 ? -93.530  -44.267 1.007   1.00 97.76  ? 444 PRO C C   1 
ATOM   11558 O O   . PRO C 1 384 ? -93.812  -44.630 -0.112  1.00 115.31 ? 444 PRO C O   1 
ATOM   11559 C CB  . PRO C 1 384 ? -93.445  -46.516 2.194   1.00 100.48 ? 444 PRO C CB  1 
ATOM   11560 C CG  . PRO C 1 384 ? -94.568  -47.375 2.751   1.00 92.58  ? 444 PRO C CG  1 
ATOM   11561 C CD  . PRO C 1 384 ? -95.838  -46.763 2.181   1.00 86.04  ? 444 PRO C CD  1 
ATOM   11562 N N   . LEU C 1 385 ? -92.847  -43.155 1.289   1.00 86.31  ? 445 LEU C N   1 
ATOM   11563 C CA  . LEU C 1 385 ? -92.219  -42.281 0.260   1.00 87.53  ? 445 LEU C CA  1 
ATOM   11564 C C   . LEU C 1 385 ? -90.705  -42.335 0.453   1.00 85.05  ? 445 LEU C C   1 
ATOM   11565 O O   . LEU C 1 385 ? -90.289  -42.381 1.609   1.00 93.72  ? 445 LEU C O   1 
ATOM   11566 C CB  . LEU C 1 385 ? -92.740  -40.850 0.391   1.00 87.68  ? 445 LEU C CB  1 
ATOM   11567 C CG  . LEU C 1 385 ? -94.117  -40.591 -0.216  1.00 88.53  ? 445 LEU C CG  1 
ATOM   11568 C CD1 . LEU C 1 385 ? -95.001  -39.913 0.805   1.00 102.09 ? 445 LEU C CD1 1 
ATOM   11569 C CD2 . LEU C 1 385 ? -94.062  -39.752 -1.477  1.00 87.56  ? 445 LEU C CD2 1 
ATOM   11570 N N   . LYS C 1 386 ? -89.943  -42.336 -0.640  1.00 88.96  ? 446 LYS C N   1 
ATOM   11571 C CA  . LYS C 1 386 ? -88.556  -42.860 -0.711  1.00 76.97  ? 446 LYS C CA  1 
ATOM   11572 C C   . LYS C 1 386 ? -87.596  -41.702 -0.441  1.00 71.19  ? 446 LYS C C   1 
ATOM   11573 O O   . LYS C 1 386 ? -86.730  -41.878 0.414   1.00 57.43  ? 446 LYS C O   1 
ATOM   11574 C CB  . LYS C 1 386 ? -88.249  -43.503 -2.078  1.00 101.65 ? 446 LYS C CB  1 
ATOM   11575 C CG  . LYS C 1 386 ? -89.284  -43.341 -3.215  1.00 109.75 ? 446 LYS C CG  1 
ATOM   11576 C CD  . LYS C 1 386 ? -90.541  -44.202 -3.093  1.00 90.98  ? 446 LYS C CD  1 
ATOM   11577 C CE  . LYS C 1 386 ? -91.501  -43.952 -4.225  1.00 74.24  ? 446 LYS C CE  1 
ATOM   11578 N NZ  . LYS C 1 386 ? -91.856  -42.519 -4.296  1.00 67.64  ? 446 LYS C NZ  1 
ATOM   11579 N N   . THR C 1 387 ? -87.757  -40.566 -1.139  1.00 74.22  ? 447 THR C N   1 
ATOM   11580 C CA  . THR C 1 387 ? -86.855  -39.397 -0.973  1.00 80.27  ? 447 THR C CA  1 
ATOM   11581 C C   . THR C 1 387 ? -87.623  -38.194 -0.445  1.00 64.72  ? 447 THR C C   1 
ATOM   11582 O O   . THR C 1 387 ? -88.831  -38.172 -0.617  1.00 52.72  ? 447 THR C O   1 
ATOM   11583 C CB  . THR C 1 387 ? -86.153  -39.030 -2.278  1.00 89.29  ? 447 THR C CB  1 
ATOM   11584 O OG1 . THR C 1 387 ? -85.201  -38.019 -1.951  1.00 98.08  ? 447 THR C OG1 1 
ATOM   11585 C CG2 . THR C 1 387 ? -87.111  -38.570 -3.347  1.00 96.64  ? 447 THR C CG2 1 
ATOM   11586 N N   . LEU C 1 388 ? -86.920  -37.232 0.161   1.00 70.00  ? 448 LEU C N   1 
ATOM   11587 C CA  . LEU C 1 388 ? -87.472  -35.917 0.601   1.00 77.64  ? 448 LEU C CA  1 
ATOM   11588 C C   . LEU C 1 388 ? -88.190  -35.282 -0.586  1.00 68.76  ? 448 LEU C C   1 
ATOM   11589 O O   . LEU C 1 388 ? -89.251  -34.718 -0.376  1.00 70.69  ? 448 LEU C O   1 
ATOM   11590 C CB  . LEU C 1 388 ? -86.375  -34.975 1.118   1.00 78.83  ? 448 LEU C CB  1 
ATOM   11591 C CG  . LEU C 1 388 ? -86.789  -33.512 1.330   1.00 83.90  ? 448 LEU C CG  1 
ATOM   11592 C CD1 . LEU C 1 388 ? -87.829  -33.389 2.435   1.00 86.29  ? 448 LEU C CD1 1 
ATOM   11593 C CD2 . LEU C 1 388 ? -85.579  -32.641 1.663   1.00 88.22  ? 448 LEU C CD2 1 
ATOM   11594 N N   . TYR C 1 389 ? -87.643  -35.367 -1.787  1.00 64.53  ? 449 TYR C N   1 
ATOM   11595 C CA  . TYR C 1 389 ? -88.306  -34.760 -2.965  1.00 83.20  ? 449 TYR C CA  1 
ATOM   11596 C C   . TYR C 1 389 ? -89.724  -35.342 -3.160  1.00 82.89  ? 449 TYR C C   1 
ATOM   11597 O O   . TYR C 1 389 ? -90.661  -34.597 -3.454  1.00 86.49  ? 449 TYR C O   1 
ATOM   11598 C CB  . TYR C 1 389 ? -87.467  -34.927 -4.225  1.00 85.45  ? 449 TYR C CB  1 
ATOM   11599 C CG  . TYR C 1 389 ? -88.084  -34.212 -5.390  1.00 77.41  ? 449 TYR C CG  1 
ATOM   11600 C CD1 . TYR C 1 389 ? -88.072  -32.830 -5.439  1.00 80.41  ? 449 TYR C CD1 1 
ATOM   11601 C CD2 . TYR C 1 389 ? -88.719  -34.902 -6.402  1.00 76.96  ? 449 TYR C CD2 1 
ATOM   11602 C CE1 . TYR C 1 389 ? -88.637  -32.136 -6.497  1.00 81.39  ? 449 TYR C CE1 1 
ATOM   11603 C CE2 . TYR C 1 389 ? -89.253  -34.229 -7.492  1.00 79.18  ? 449 TYR C CE2 1 
ATOM   11604 C CZ  . TYR C 1 389 ? -89.239  -32.836 -7.525  1.00 78.32  ? 449 TYR C CZ  1 
ATOM   11605 O OH  . TYR C 1 389 ? -89.785  -32.090 -8.531  1.00 53.13  ? 449 TYR C OH  1 
ATOM   11606 N N   . ASP C 1 390 ? -89.895  -36.648 -2.983  1.00 88.78  ? 450 ASP C N   1 
ATOM   11607 C CA  . ASP C 1 390 ? -91.208  -37.323 -3.138  1.00 88.14  ? 450 ASP C CA  1 
ATOM   11608 C C   . ASP C 1 390 ? -92.163  -36.854 -2.047  1.00 80.73  ? 450 ASP C C   1 
ATOM   11609 O O   . ASP C 1 390 ? -93.318  -36.519 -2.362  1.00 61.32  ? 450 ASP C O   1 
ATOM   11610 C CB  . ASP C 1 390 ? -91.023  -38.835 -3.108  1.00 92.71  ? 450 ASP C CB  1 
ATOM   11611 C CG  . ASP C 1 390 ? -90.598  -39.347 -4.466  1.00 100.08 ? 450 ASP C CG  1 
ATOM   11612 O OD1 . ASP C 1 390 ? -90.460  -38.495 -5.425  1.00 86.44  ? 450 ASP C OD1 1 
ATOM   11613 O OD2 . ASP C 1 390 ? -90.445  -40.587 -4.558  1.00 98.40  ? 450 ASP C OD2 1 
ATOM   11614 N N   . ALA C 1 391 ? -91.694  -36.850 -0.809  1.00 76.66  ? 451 ALA C N   1 
ATOM   11615 C CA  . ALA C 1 391 ? -92.459  -36.307 0.335   1.00 73.24  ? 451 ALA C CA  1 
ATOM   11616 C C   . ALA C 1 391 ? -92.825  -34.846 0.028   1.00 73.48  ? 451 ALA C C   1 
ATOM   11617 O O   . ALA C 1 391 ? -93.997  -34.530 0.163   1.00 74.85  ? 451 ALA C O   1 
ATOM   11618 C CB  . ALA C 1 391 ? -91.691  -36.457 1.635   1.00 79.72  ? 451 ALA C CB  1 
ATOM   11619 N N   . VAL C 1 392 ? -91.895  -33.982 -0.399  1.00 65.77  ? 452 VAL C N   1 
ATOM   11620 C CA  . VAL C 1 392 ? -92.197  -32.529 -0.568  1.00 66.99  ? 452 VAL C CA  1 
ATOM   11621 C C   . VAL C 1 392 ? -93.397  -32.428 -1.514  1.00 74.94  ? 452 VAL C C   1 
ATOM   11622 O O   . VAL C 1 392 ? -94.290  -31.593 -1.274  1.00 68.19  ? 452 VAL C O   1 
ATOM   11623 C CB  . VAL C 1 392 ? -90.994  -31.700 -1.072  1.00 64.89  ? 452 VAL C CB  1 
ATOM   11624 C CG1 . VAL C 1 392 ? -91.397  -30.335 -1.639  1.00 56.99  ? 452 VAL C CG1 1 
ATOM   11625 C CG2 . VAL C 1 392 ? -89.972  -31.515 0.033   1.00 69.81  ? 452 VAL C CG2 1 
ATOM   11626 N N   . GLN C 1 393 ? -93.437  -33.279 -2.538  1.00 79.55  ? 453 GLN C N   1 
ATOM   11627 C CA  . GLN C 1 393 ? -94.458  -33.199 -3.609  1.00 72.37  ? 453 GLN C CA  1 
ATOM   11628 C C   . GLN C 1 393 ? -95.791  -33.753 -3.100  1.00 73.00  ? 453 GLN C C   1 
ATOM   11629 O O   . GLN C 1 393 ? -96.819  -33.148 -3.436  1.00 71.28  ? 453 GLN C O   1 
ATOM   11630 C CB  . GLN C 1 393 ? -93.962  -33.899 -4.871  1.00 76.95  ? 453 GLN C CB  1 
ATOM   11631 C CG  . GLN C 1 393 ? -92.868  -33.119 -5.585  1.00 88.67  ? 453 GLN C CG  1 
ATOM   11632 C CD  . GLN C 1 393 ? -93.380  -31.941 -6.383  1.00 88.02  ? 453 GLN C CD  1 
ATOM   11633 O OE1 . GLN C 1 393 ? -93.953  -30.985 -5.846  1.00 88.54  ? 453 GLN C OE1 1 
ATOM   11634 N NE2 . GLN C 1 393 ? -93.142  -31.991 -7.686  1.00 89.35  ? 453 GLN C NE2 1 
ATOM   11635 N N   . SER C 1 394 ? -95.771  -34.847 -2.324  1.00 70.15  ? 454 SER C N   1 
ATOM   11636 C CA  . SER C 1 394 ? -96.982  -35.547 -1.808  1.00 60.78  ? 454 SER C CA  1 
ATOM   11637 C C   . SER C 1 394 ? -97.602  -34.736 -0.648  1.00 63.82  ? 454 SER C C   1 
ATOM   11638 O O   . SER C 1 394 ? -98.789  -34.415 -0.734  1.00 59.17  ? 454 SER C O   1 
ATOM   11639 C CB  . SER C 1 394 ? -96.633  -36.976 -1.421  1.00 58.55  ? 454 SER C CB  1 
ATOM   11640 O OG  . SER C 1 394 ? -97.730  -37.657 -0.846  1.00 53.78  ? 454 SER C OG  1 
ATOM   11641 N N   . ILE C 1 395 ? -96.813  -34.390 0.380   1.00 62.20  ? 455 ILE C N   1 
ATOM   11642 C CA  . ILE C 1 395 ? -97.265  -33.684 1.618   1.00 57.45  ? 455 ILE C CA  1 
ATOM   11643 C C   . ILE C 1 395 ? -97.599  -32.228 1.292   1.00 52.37  ? 455 ILE C C   1 
ATOM   11644 O O   . ILE C 1 395 ? -98.446  -31.670 1.963   1.00 52.61  ? 455 ILE C O   1 
ATOM   11645 C CB  . ILE C 1 395 ? -96.217  -33.774 2.749   1.00 65.72  ? 455 ILE C CB  1 
ATOM   11646 C CG1 . ILE C 1 395 ? -96.247  -35.133 3.464   1.00 69.73  ? 455 ILE C CG1 1 
ATOM   11647 C CG2 . ILE C 1 395 ? -96.408  -32.653 3.763   1.00 62.76  ? 455 ILE C CG2 1 
ATOM   11648 C CD1 . ILE C 1 395 ? -96.094  -36.328 2.571   1.00 68.96  ? 455 ILE C CD1 1 
ATOM   11649 N N   . LYS C 1 396 ? -96.946  -31.633 0.310   1.00 58.15  ? 456 LYS C N   1 
ATOM   11650 C CA  . LYS C 1 396 ? -97.195  -30.224 -0.123  1.00 62.27  ? 456 LYS C CA  1 
ATOM   11651 C C   . LYS C 1 396 ? -97.076  -29.299 1.080   1.00 54.90  ? 456 LYS C C   1 
ATOM   11652 O O   . LYS C 1 396 ? -97.953  -28.484 1.323   1.00 47.90  ? 456 LYS C O   1 
ATOM   11653 C CB  . LYS C 1 396 ? -98.567  -30.052 -0.787  1.00 67.83  ? 456 LYS C CB  1 
ATOM   11654 C CG  . LYS C 1 396 ? -98.594  -29.886 -2.306  1.00 68.87  ? 456 LYS C CG  1 
ATOM   11655 C CD  . LYS C 1 396 ? -99.322  -31.062 -2.985  1.00 82.23  ? 456 LYS C CD  1 
ATOM   11656 C CE  . LYS C 1 396 ? -99.363  -31.012 -4.492  1.00 83.86  ? 456 LYS C CE  1 
ATOM   11657 N NZ  . LYS C 1 396 ? -100.013 -29.756 -4.935  1.00 92.78  ? 456 LYS C NZ  1 
ATOM   11658 N N   . PRO C 1 397 ? -95.948  -29.347 1.816   1.00 54.25  ? 457 PRO C N   1 
ATOM   11659 C CA  . PRO C 1 397 ? -95.801  -28.577 3.045   1.00 57.88  ? 457 PRO C CA  1 
ATOM   11660 C C   . PRO C 1 397 ? -95.734  -27.053 2.870   1.00 54.90  ? 457 PRO C C   1 
ATOM   11661 O O   . PRO C 1 397 ? -95.430  -26.594 1.826   1.00 57.84  ? 457 PRO C O   1 
ATOM   11662 C CB  . PRO C 1 397 ? -94.469  -29.115 3.595   1.00 61.77  ? 457 PRO C CB  1 
ATOM   11663 C CG  . PRO C 1 397 ? -93.688  -29.492 2.380   1.00 53.37  ? 457 PRO C CG  1 
ATOM   11664 C CD  . PRO C 1 397 ? -94.723  -30.074 1.459   1.00 56.30  ? 457 PRO C CD  1 
ATOM   11665 N N   . THR C 1 398 ? -96.039  -26.315 3.933   1.00 63.39  ? 458 THR C N   1 
ATOM   11666 C CA  . THR C 1 398 ? -95.926  -24.823 3.998   1.00 70.87  ? 458 THR C CA  1 
ATOM   11667 C C   . THR C 1 398 ? -94.606  -24.451 4.673   1.00 63.70  ? 458 THR C C   1 
ATOM   11668 O O   . THR C 1 398 ? -94.175  -23.295 4.490   1.00 62.08  ? 458 THR C O   1 
ATOM   11669 C CB  . THR C 1 398 ? -97.119  -24.173 4.728   1.00 73.72  ? 458 THR C CB  1 
ATOM   11670 O OG1 . THR C 1 398 ? -97.245  -24.564 6.102   1.00 65.57  ? 458 THR C OG1 1 
ATOM   11671 C CG2 . THR C 1 398 ? -98.427  -24.506 4.046   1.00 85.48  ? 458 THR C CG2 1 
ATOM   11672 N N   . VAL C 1 399 ? -94.017  -25.395 5.423   1.00 61.30  ? 459 VAL C N   1 
ATOM   11673 C CA  . VAL C 1 399 ? -92.767  -25.200 6.211   1.00 56.95  ? 459 VAL C CA  1 
ATOM   11674 C C   . VAL C 1 399 ? -91.859  -26.422 6.030   1.00 55.56  ? 459 VAL C C   1 
ATOM   11675 O O   . VAL C 1 399 ? -92.290  -27.564 6.392   1.00 41.82  ? 459 VAL C O   1 
ATOM   11676 C CB  . VAL C 1 399 ? -93.063  -24.981 7.698   1.00 61.28  ? 459 VAL C CB  1 
ATOM   11677 C CG1 . VAL C 1 399 ? -91.782  -24.796 8.475   1.00 73.05  ? 459 VAL C CG1 1 
ATOM   11678 C CG2 . VAL C 1 399 ? -93.975  -23.799 7.932   1.00 70.60  ? 459 VAL C CG2 1 
ATOM   11679 N N   . LEU C 1 400 ? -90.651  -26.167 5.508   1.00 53.35  ? 460 LEU C N   1 
ATOM   11680 C CA  . LEU C 1 400 ? -89.602  -27.180 5.256   1.00 56.97  ? 460 LEU C CA  1 
ATOM   11681 C C   . LEU C 1 400 ? -88.410  -26.879 6.169   1.00 61.74  ? 460 LEU C C   1 
ATOM   11682 O O   . LEU C 1 400 ? -87.758  -25.857 5.961   1.00 61.32  ? 460 LEU C O   1 
ATOM   11683 C CB  . LEU C 1 400 ? -89.185  -27.127 3.791   1.00 53.01  ? 460 LEU C CB  1 
ATOM   11684 C CG  . LEU C 1 400 ? -88.115  -28.151 3.389   1.00 57.34  ? 460 LEU C CG  1 
ATOM   11685 C CD1 . LEU C 1 400 ? -88.653  -29.581 3.483   1.00 53.23  ? 460 LEU C CD1 1 
ATOM   11686 C CD2 . LEU C 1 400 ? -87.565  -27.853 1.996   1.00 52.29  ? 460 LEU C CD2 1 
ATOM   11687 N N   . ILE C 1 401 ? -88.160  -27.757 7.140   1.00 68.74  ? 461 ILE C N   1 
ATOM   11688 C CA  . ILE C 1 401 ? -87.102  -27.619 8.179   1.00 62.81  ? 461 ILE C CA  1 
ATOM   11689 C C   . ILE C 1 401 ? -86.099  -28.761 8.012   1.00 64.88  ? 461 ILE C C   1 
ATOM   11690 O O   . ILE C 1 401 ? -86.507  -29.934 7.954   1.00 68.66  ? 461 ILE C O   1 
ATOM   11691 C CB  . ILE C 1 401 ? -87.705  -27.602 9.592   1.00 60.87  ? 461 ILE C CB  1 
ATOM   11692 C CG1 . ILE C 1 401 ? -88.592  -26.386 9.840   1.00 65.17  ? 461 ILE C CG1 1 
ATOM   11693 C CG2 . ILE C 1 401 ? -86.601  -27.648 10.605  1.00 61.98  ? 461 ILE C CG2 1 
ATOM   11694 C CD1 . ILE C 1 401 ? -89.444  -26.488 11.083  1.00 68.45  ? 461 ILE C CD1 1 
ATOM   11695 N N   . GLY C 1 402 ? -84.819  -28.411 7.925   1.00 64.80  ? 462 GLY C N   1 
ATOM   11696 C CA  . GLY C 1 402 ? -83.725  -29.376 7.756   1.00 68.45  ? 462 GLY C CA  1 
ATOM   11697 C C   . GLY C 1 402 ? -82.895  -29.484 9.018   1.00 67.16  ? 462 GLY C C   1 
ATOM   11698 O O   . GLY C 1 402 ? -82.271  -28.478 9.423   1.00 66.35  ? 462 GLY C O   1 
ATOM   11699 N N   . THR C 1 403 ? -82.867  -30.681 9.594   1.00 68.10  ? 463 THR C N   1 
ATOM   11700 C CA  . THR C 1 403 ? -82.035  -31.027 10.768  1.00 70.31  ? 463 THR C CA  1 
ATOM   11701 C C   . THR C 1 403 ? -81.267  -32.315 10.471  1.00 69.78  ? 463 THR C C   1 
ATOM   11702 O O   . THR C 1 403 ? -81.229  -33.176 11.327  1.00 73.31  ? 463 THR C O   1 
ATOM   11703 C CB  . THR C 1 403 ? -82.925  -31.149 12.006  1.00 73.94  ? 463 THR C CB  1 
ATOM   11704 O OG1 . THR C 1 403 ? -83.985  -32.063 11.717  1.00 70.98  ? 463 THR C OG1 1 
ATOM   11705 C CG2 . THR C 1 403 ? -83.469  -29.813 12.454  1.00 79.18  ? 463 THR C CG2 1 
ATOM   11706 N N   . SER C 1 404 ? -80.696  -32.447 9.275   1.00 80.54  ? 464 SER C N   1 
ATOM   11707 C CA  . SER C 1 404 ? -80.160  -33.731 8.740   1.00 76.04  ? 464 SER C CA  1 
ATOM   11708 C C   . SER C 1 404 ? -78.713  -33.919 9.177   1.00 63.16  ? 464 SER C C   1 
ATOM   11709 O O   . SER C 1 404 ? -78.275  -35.064 9.244   1.00 72.61  ? 464 SER C O   1 
ATOM   11710 C CB  . SER C 1 404 ? -80.290  -33.790 7.229   1.00 71.49  ? 464 SER C CB  1 
ATOM   11711 O OG  . SER C 1 404 ? -80.083  -32.502 6.648   1.00 73.27  ? 464 SER C OG  1 
ATOM   11712 N N   . GLY C 1 405 ? -78.006  -32.817 9.369   1.00 59.27  ? 465 GLY C N   1 
ATOM   11713 C CA  . GLY C 1 405 ? -76.536  -32.771 9.486   1.00 59.05  ? 465 GLY C CA  1 
ATOM   11714 C C   . GLY C 1 405 ? -75.837  -32.908 8.140   1.00 64.17  ? 465 GLY C C   1 
ATOM   11715 O O   . GLY C 1 405 ? -74.604  -33.082 8.153   1.00 74.94  ? 465 GLY C O   1 
ATOM   11716 N N   . VAL C 1 406 ? -76.569  -32.825 7.016   1.00 62.46  ? 466 VAL C N   1 
ATOM   11717 C CA  . VAL C 1 406 ? -76.046  -33.122 5.641   1.00 48.30  ? 466 VAL C CA  1 
ATOM   11718 C C   . VAL C 1 406 ? -76.256  -31.893 4.755   1.00 51.20  ? 466 VAL C C   1 
ATOM   11719 O O   . VAL C 1 406 ? -77.394  -31.395 4.656   1.00 56.47  ? 466 VAL C O   1 
ATOM   11720 C CB  . VAL C 1 406 ? -76.724  -34.351 5.016   1.00 40.65  ? 466 VAL C CB  1 
ATOM   11721 C CG1 . VAL C 1 406 ? -76.060  -34.721 3.708   1.00 42.77  ? 466 VAL C CG1 1 
ATOM   11722 C CG2 . VAL C 1 406 ? -76.751  -35.524 5.979   1.00 43.79  ? 466 VAL C CG2 1 
ATOM   11723 N N   . GLY C 1 407 ? -75.197  -31.434 4.115   1.00 54.42  ? 467 GLY C N   1 
ATOM   11724 C CA  . GLY C 1 407 ? -75.224  -30.211 3.310   1.00 51.91  ? 467 GLY C CA  1 
ATOM   11725 C C   . GLY C 1 407 ? -75.905  -30.461 1.986   1.00 62.53  ? 467 GLY C C   1 
ATOM   11726 O O   . GLY C 1 407 ? -75.886  -31.611 1.510   1.00 67.71  ? 467 GLY C O   1 
ATOM   11727 N N   . ARG C 1 408 ? -76.521  -29.408 1.445   1.00 75.35  ? 468 ARG C N   1 
ATOM   11728 C CA  . ARG C 1 408 ? -76.981  -29.313 0.039   1.00 67.52  ? 468 ARG C CA  1 
ATOM   11729 C C   . ARG C 1 408 ? -77.972  -30.464 -0.242  1.00 62.79  ? 468 ARG C C   1 
ATOM   11730 O O   . ARG C 1 408 ? -77.971  -30.988 -1.369  1.00 70.55  ? 468 ARG C O   1 
ATOM   11731 C CB  . ARG C 1 408 ? -75.711  -29.232 -0.832  1.00 64.05  ? 468 ARG C CB  1 
ATOM   11732 C CG  . ARG C 1 408 ? -74.666  -28.210 -0.383  1.00 63.92  ? 468 ARG C CG  1 
ATOM   11733 C CD  . ARG C 1 408 ? -75.092  -26.725 -0.427  1.00 71.33  ? 468 ARG C CD  1 
ATOM   11734 N NE  . ARG C 1 408 ? -74.007  -25.729 -0.400  1.00 67.07  ? 468 ARG C NE  1 
ATOM   11735 C CZ  . ARG C 1 408 ? -73.184  -25.434 -1.441  1.00 72.47  ? 468 ARG C CZ  1 
ATOM   11736 N NH1 . ARG C 1 408 ? -73.300  -26.043 -2.615  1.00 62.74  ? 468 ARG C NH1 1 
ATOM   11737 N NH2 . ARG C 1 408 ? -72.236  -24.520 -1.315  1.00 70.65  ? 468 ARG C NH2 1 
ATOM   11738 N N   . THR C 1 409 ? -78.832  -30.812 0.729   1.00 63.59  ? 469 THR C N   1 
ATOM   11739 C CA  . THR C 1 409 ? -79.941  -31.814 0.592   1.00 66.47  ? 469 THR C CA  1 
ATOM   11740 C C   . THR C 1 409 ? -81.263  -31.119 0.221   1.00 54.80  ? 469 THR C C   1 
ATOM   11741 O O   . THR C 1 409 ? -82.184  -31.814 -0.268  1.00 44.42  ? 469 THR C O   1 
ATOM   11742 C CB  . THR C 1 409 ? -80.106  -32.653 1.863   1.00 61.78  ? 469 THR C CB  1 
ATOM   11743 O OG1 . THR C 1 409 ? -80.128  -31.733 2.952   1.00 70.47  ? 469 THR C OG1 1 
ATOM   11744 C CG2 . THR C 1 409 ? -79.004  -33.674 2.064   1.00 53.99  ? 469 THR C CG2 1 
ATOM   11745 N N   . PHE C 1 410 ? -81.339  -29.807 0.477   1.00 62.23  ? 470 PHE C N   1 
ATOM   11746 C CA  . PHE C 1 410 ? -82.367  -28.876 -0.059  1.00 57.91  ? 470 PHE C CA  1 
ATOM   11747 C C   . PHE C 1 410 ? -81.910  -28.399 -1.431  1.00 66.52  ? 470 PHE C C   1 
ATOM   11748 O O   . PHE C 1 410 ? -81.208  -27.365 -1.500  1.00 81.36  ? 470 PHE C O   1 
ATOM   11749 C CB  . PHE C 1 410 ? -82.631  -27.712 0.899   1.00 52.84  ? 470 PHE C CB  1 
ATOM   11750 C CG  . PHE C 1 410 ? -83.396  -28.093 2.145   1.00 55.31  ? 470 PHE C CG  1 
ATOM   11751 C CD1 . PHE C 1 410 ? -83.623  -29.437 2.468   1.00 49.90  ? 470 PHE C CD1 1 
ATOM   11752 C CD2 . PHE C 1 410 ? -83.822  -27.101 3.018   1.00 49.70  ? 470 PHE C CD2 1 
ATOM   11753 C CE1 . PHE C 1 410 ? -84.300  -29.777 3.622   1.00 47.93  ? 470 PHE C CE1 1 
ATOM   11754 C CE2 . PHE C 1 410 ? -84.484  -27.449 4.180   1.00 57.42  ? 470 PHE C CE2 1 
ATOM   11755 C CZ  . PHE C 1 410 ? -84.727  -28.784 4.472   1.00 58.94  ? 470 PHE C CZ  1 
ATOM   11756 N N   . THR C 1 411 ? -82.304  -29.168 -2.455  1.00 75.61  ? 471 THR C N   1 
ATOM   11757 C CA  . THR C 1 411 ? -81.875  -29.082 -3.884  1.00 69.97  ? 471 THR C CA  1 
ATOM   11758 C C   . THR C 1 411 ? -82.694  -27.986 -4.589  1.00 68.02  ? 471 THR C C   1 
ATOM   11759 O O   . THR C 1 411 ? -83.685  -27.528 -3.992  1.00 74.22  ? 471 THR C O   1 
ATOM   11760 C CB  . THR C 1 411 ? -81.983  -30.490 -4.502  1.00 54.78  ? 471 THR C CB  1 
ATOM   11761 O OG1 . THR C 1 411 ? -83.338  -30.922 -4.426  1.00 61.26  ? 471 THR C OG1 1 
ATOM   11762 C CG2 . THR C 1 411 ? -81.166  -31.525 -3.764  1.00 52.31  ? 471 THR C CG2 1 
ATOM   11763 N N   . LYS C 1 412 ? -82.313  -27.589 -5.801  1.00 67.29  ? 472 LYS C N   1 
ATOM   11764 C CA  . LYS C 1 412 ? -83.110  -26.616 -6.600  1.00 77.23  ? 472 LYS C CA  1 
ATOM   11765 C C   . LYS C 1 412 ? -84.500  -27.182 -6.878  1.00 83.39  ? 472 LYS C C   1 
ATOM   11766 O O   . LYS C 1 412 ? -85.445  -26.414 -6.697  1.00 93.46  ? 472 LYS C O   1 
ATOM   11767 C CB  . LYS C 1 412 ? -82.361  -26.079 -7.822  1.00 87.45  ? 472 LYS C CB  1 
ATOM   11768 C CG  . LYS C 1 412 ? -82.573  -26.649 -9.214  1.00 104.66 ? 472 LYS C CG  1 
ATOM   11769 C CD  . LYS C 1 412 ? -81.756  -25.846 -10.263 1.00 106.33 ? 472 LYS C CD  1 
ATOM   11770 C CE  . LYS C 1 412 ? -82.111  -24.372 -10.407 1.00 104.82 ? 472 LYS C CE  1 
ATOM   11771 N NZ  . LYS C 1 412 ? -83.379  -24.162 -11.148 1.00 119.03 ? 472 LYS C NZ  1 
ATOM   11772 N N   . GLU C 1 413 ? -84.619  -28.472 -7.204  1.00 78.53  ? 473 GLU C N   1 
ATOM   11773 C CA  . GLU C 1 413 ? -85.906  -29.199 -7.440  1.00 77.02  ? 473 GLU C CA  1 
ATOM   11774 C C   . GLU C 1 413 ? -86.832  -29.044 -6.227  1.00 70.78  ? 473 GLU C C   1 
ATOM   11775 O O   . GLU C 1 413 ? -88.065  -28.857 -6.424  1.00 63.42  ? 473 GLU C O   1 
ATOM   11776 C CB  . GLU C 1 413 ? -85.698  -30.703 -7.638  1.00 77.28  ? 473 GLU C CB  1 
ATOM   11777 C CG  . GLU C 1 413 ? -84.767  -31.067 -8.773  1.00 89.67  ? 473 GLU C CG  1 
ATOM   11778 C CD  . GLU C 1 413 ? -83.275  -31.035 -8.440  1.00 99.30  ? 473 GLU C CD  1 
ATOM   11779 O OE1 . GLU C 1 413 ? -82.880  -30.268 -7.557  1.00 91.72  ? 473 GLU C OE1 1 
ATOM   11780 O OE2 . GLU C 1 413 ? -82.510  -31.793 -9.054  1.00 102.87 ? 473 GLU C OE2 1 
ATOM   11781 N N   . ILE C 1 414 ? -86.252  -29.167 -5.030  1.00 57.60  ? 474 ILE C N   1 
ATOM   11782 C CA  . ILE C 1 414 ? -86.979  -29.154 -3.736  1.00 53.01  ? 474 ILE C CA  1 
ATOM   11783 C C   . ILE C 1 414 ? -87.412  -27.717 -3.424  1.00 51.11  ? 474 ILE C C   1 
ATOM   11784 O O   . ILE C 1 414 ? -88.607  -27.534 -3.212  1.00 55.73  ? 474 ILE C O   1 
ATOM   11785 C CB  . ILE C 1 414 ? -86.130  -29.816 -2.640  1.00 45.88  ? 474 ILE C CB  1 
ATOM   11786 C CG1 . ILE C 1 414 ? -86.059  -31.333 -2.876  1.00 47.61  ? 474 ILE C CG1 1 
ATOM   11787 C CG2 . ILE C 1 414 ? -86.696  -29.465 -1.285  1.00 42.53  ? 474 ILE C CG2 1 
ATOM   11788 C CD1 . ILE C 1 414 ? -85.657  -32.184 -1.683  1.00 50.16  ? 474 ILE C CD1 1 
ATOM   11789 N N   . ILE C 1 415 ? -86.505  -26.737 -3.438  1.00 43.87  ? 475 ILE C N   1 
ATOM   11790 C CA  . ILE C 1 415 ? -86.855  -25.305 -3.205  1.00 47.96  ? 475 ILE C CA  1 
ATOM   11791 C C   . ILE C 1 415 ? -87.807  -24.821 -4.308  1.00 53.25  ? 475 ILE C C   1 
ATOM   11792 O O   . ILE C 1 415 ? -88.678  -23.987 -3.993  1.00 47.81  ? 475 ILE C O   1 
ATOM   11793 C CB  . ILE C 1 415 ? -85.615  -24.383 -3.140  1.00 53.63  ? 475 ILE C CB  1 
ATOM   11794 C CG1 . ILE C 1 415 ? -84.746  -24.600 -1.915  1.00 51.29  ? 475 ILE C CG1 1 
ATOM   11795 C CG2 . ILE C 1 415 ? -86.007  -22.913 -3.172  1.00 53.24  ? 475 ILE C CG2 1 
ATOM   11796 C CD1 . ILE C 1 415 ? -84.674  -25.993 -1.446  1.00 58.60  ? 475 ILE C CD1 1 
ATOM   11797 N N   . GLU C 1 416 ? -87.631  -25.267 -5.555  1.00 53.46  ? 476 GLU C N   1 
ATOM   11798 C CA  . GLU C 1 416 ? -88.518  -24.861 -6.678  1.00 58.52  ? 476 GLU C CA  1 
ATOM   11799 C C   . GLU C 1 416 ? -89.911  -25.448 -6.439  1.00 65.52  ? 476 GLU C C   1 
ATOM   11800 O O   . GLU C 1 416 ? -90.897  -24.673 -6.517  1.00 64.76  ? 476 GLU C O   1 
ATOM   11801 C CB  . GLU C 1 416 ? -87.946  -25.265 -8.033  1.00 63.29  ? 476 GLU C CB  1 
ATOM   11802 C CG  . GLU C 1 416 ? -86.940  -24.247 -8.562  1.00 71.23  ? 476 GLU C CG  1 
ATOM   11803 C CD  . GLU C 1 416 ? -86.513  -24.436 -10.008 1.00 72.93  ? 476 GLU C CD  1 
ATOM   11804 O OE1 . GLU C 1 416 ? -86.247  -25.598 -10.387 1.00 64.32  ? 476 GLU C OE1 1 
ATOM   11805 O OE2 . GLU C 1 416 ? -86.424  -23.420 -10.744 1.00 81.61  ? 476 GLU C OE2 1 
ATOM   11806 N N   . ALA C 1 417 ? -89.988  -26.752 -6.128  1.00 70.48  ? 477 ALA C N   1 
ATOM   11807 C CA  . ALA C 1 417 ? -91.241  -27.453 -5.752  1.00 59.84  ? 477 ALA C CA  1 
ATOM   11808 C C   . ALA C 1 417 ? -91.945  -26.663 -4.647  1.00 60.62  ? 477 ALA C C   1 
ATOM   11809 O O   . ALA C 1 417 ? -93.103  -26.350 -4.823  1.00 57.50  ? 477 ALA C O   1 
ATOM   11810 C CB  . ALA C 1 417 ? -90.959  -28.863 -5.316  1.00 60.39  ? 477 ALA C CB  1 
ATOM   11811 N N   . MET C 1 418 ? -91.249  -26.334 -3.561  1.00 59.53  ? 478 MET C N   1 
ATOM   11812 C CA  . MET C 1 418 ? -91.796  -25.568 -2.404  1.00 60.42  ? 478 MET C CA  1 
ATOM   11813 C C   . MET C 1 418 ? -92.269  -24.171 -2.812  1.00 59.59  ? 478 MET C C   1 
ATOM   11814 O O   . MET C 1 418 ? -93.223  -23.691 -2.177  1.00 58.04  ? 478 MET C O   1 
ATOM   11815 C CB  . MET C 1 418 ? -90.747  -25.395 -1.302  1.00 60.52  ? 478 MET C CB  1 
ATOM   11816 C CG  . MET C 1 418 ? -90.414  -26.687 -0.595  1.00 60.26  ? 478 MET C CG  1 
ATOM   11817 S SD  . MET C 1 418 ? -91.597  -27.110 0.685   1.00 63.76  ? 478 MET C SD  1 
ATOM   11818 C CE  . MET C 1 418 ? -91.951  -25.505 1.423   1.00 52.85  ? 478 MET C CE  1 
ATOM   11819 N N   . SER C 1 419 ? -91.597  -23.539 -3.781  1.00 59.14  ? 479 SER C N   1 
ATOM   11820 C CA  . SER C 1 419 ? -91.907  -22.163 -4.247  1.00 64.28  ? 479 SER C CA  1 
ATOM   11821 C C   . SER C 1 419 ? -93.138  -22.194 -5.151  1.00 57.73  ? 479 SER C C   1 
ATOM   11822 O O   . SER C 1 419 ? -93.759  -21.136 -5.340  1.00 42.93  ? 479 SER C O   1 
ATOM   11823 C CB  . SER C 1 419 ? -90.709  -21.544 -4.949  1.00 67.17  ? 479 SER C CB  1 
ATOM   11824 O OG  . SER C 1 419 ? -89.518  -21.639 -4.170  1.00 60.33  ? 479 SER C OG  1 
ATOM   11825 N N   . SER C 1 420 ? -93.454  -23.380 -5.681  1.00 65.96  ? 480 SER C N   1 
ATOM   11826 C CA  . SER C 1 420 ? -94.522  -23.630 -6.687  1.00 63.13  ? 480 SER C CA  1 
ATOM   11827 C C   . SER C 1 420 ? -95.903  -23.685 -6.017  1.00 58.51  ? 480 SER C C   1 
ATOM   11828 O O   . SER C 1 420 ? -96.810  -23.088 -6.614  1.00 65.89  ? 480 SER C O   1 
ATOM   11829 C CB  . SER C 1 420 ? -94.219  -24.876 -7.517  1.00 66.86  ? 480 SER C CB  1 
ATOM   11830 O OG  . SER C 1 420 ? -94.846  -26.049 -6.986  1.00 80.01  ? 480 SER C OG  1 
ATOM   11831 N N   . PHE C 1 421 ? -96.070  -24.342 -4.855  1.00 60.12  ? 481 PHE C N   1 
ATOM   11832 C CA  . PHE C 1 421 ? -97.396  -24.509 -4.193  1.00 67.26  ? 481 PHE C CA  1 
ATOM   11833 C C   . PHE C 1 421 ? -97.638  -23.430 -3.133  1.00 64.25  ? 481 PHE C C   1 
ATOM   11834 O O   . PHE C 1 421 ? -98.774  -22.979 -2.999  1.00 90.62  ? 481 PHE C O   1 
ATOM   11835 C CB  . PHE C 1 421 ? -97.596  -25.825 -3.442  1.00 68.52  ? 481 PHE C CB  1 
ATOM   11836 C CG  . PHE C 1 421 ? -96.736  -26.988 -3.828  1.00 77.78  ? 481 PHE C CG  1 
ATOM   11837 C CD1 . PHE C 1 421 ? -96.892  -27.595 -5.067  1.00 92.89  ? 481 PHE C CD1 1 
ATOM   11838 C CD2 . PHE C 1 421 ? -95.783  -27.474 -2.943  1.00 77.88  ? 481 PHE C CD2 1 
ATOM   11839 C CE1 . PHE C 1 421 ? -96.110  -28.688 -5.415  1.00 108.83 ? 481 PHE C CE1 1 
ATOM   11840 C CE2 . PHE C 1 421 ? -95.012  -28.582 -3.283  1.00 81.44  ? 481 PHE C CE2 1 
ATOM   11841 C CZ  . PHE C 1 421 ? -95.159  -29.164 -4.527  1.00 105.39 ? 481 PHE C CZ  1 
ATOM   11842 N N   . ASN C 1 422 ? -96.606  -23.070 -2.380  1.00 63.66  ? 482 ASN C N   1 
ATOM   11843 C CA  . ASN C 1 422 ? -96.636  -21.937 -1.421  1.00 62.18  ? 482 ASN C CA  1 
ATOM   11844 C C   . ASN C 1 422 ? -96.214  -20.664 -2.156  1.00 60.46  ? 482 ASN C C   1 
ATOM   11845 O O   . ASN C 1 422 ? -95.366  -20.746 -3.079  1.00 59.02  ? 482 ASN C O   1 
ATOM   11846 C CB  . ASN C 1 422 ? -95.723  -22.187 -0.224  1.00 64.29  ? 482 ASN C CB  1 
ATOM   11847 C CG  . ASN C 1 422 ? -95.967  -23.530 0.442   1.00 60.50  ? 482 ASN C CG  1 
ATOM   11848 O OD1 . ASN C 1 422 ? -97.025  -23.779 1.024   1.00 55.49  ? 482 ASN C OD1 1 
ATOM   11849 N ND2 . ASN C 1 422 ? -94.968  -24.399 0.405   1.00 66.22  ? 482 ASN C ND2 1 
ATOM   11850 N N   . GLU C 1 423 ? -96.811  -19.529 -1.791  1.00 65.37  ? 483 GLU C N   1 
ATOM   11851 C CA  . GLU C 1 423 ? -96.492  -18.215 -2.405  1.00 69.85  ? 483 GLU C CA  1 
ATOM   11852 C C   . GLU C 1 423 ? -95.262  -17.653 -1.692  1.00 69.04  ? 483 GLU C C   1 
ATOM   11853 O O   . GLU C 1 423 ? -94.458  -17.018 -2.361  1.00 72.46  ? 483 GLU C O   1 
ATOM   11854 C CB  . GLU C 1 423 ? -97.686  -17.259 -2.282  1.00 81.90  ? 483 GLU C CB  1 
ATOM   11855 C CG  . GLU C 1 423 ? -97.957  -16.321 -3.473  1.00 87.75  ? 483 GLU C CG  1 
ATOM   11856 C CD  . GLU C 1 423 ? -96.785  -15.664 -4.202  1.00 94.52  ? 483 GLU C CD  1 
ATOM   11857 O OE1 . GLU C 1 423 ? -96.209  -16.364 -5.045  1.00 109.86 ? 483 GLU C OE1 1 
ATOM   11858 O OE2 . GLU C 1 423 ? -96.450  -14.455 -3.953  1.00 82.67  ? 483 GLU C OE2 1 
ATOM   11859 N N   . ARG C 1 424 ? -95.134  -17.876 -0.375  1.00 72.62  ? 484 ARG C N   1 
ATOM   11860 C CA  . ARG C 1 424 ? -93.940  -17.503 0.435   1.00 67.34  ? 484 ARG C CA  1 
ATOM   11861 C C   . ARG C 1 424 ? -93.547  -18.699 1.289   1.00 57.28  ? 484 ARG C C   1 
ATOM   11862 O O   . ARG C 1 424 ? -93.903  -18.717 2.455   1.00 69.96  ? 484 ARG C O   1 
ATOM   11863 C CB  . ARG C 1 424 ? -94.251  -16.254 1.270   1.00 65.28  ? 484 ARG C CB  1 
ATOM   11864 C CG  . ARG C 1 424 ? -94.830  -15.106 0.451   1.00 72.93  ? 484 ARG C CG  1 
ATOM   11865 C CD  . ARG C 1 424 ? -94.487  -13.719 0.966   1.00 76.65  ? 484 ARG C CD  1 
ATOM   11866 N NE  . ARG C 1 424 ? -93.063  -13.555 1.190   1.00 72.19  ? 484 ARG C NE  1 
ATOM   11867 C CZ  . ARG C 1 424 ? -92.278  -12.668 0.609   1.00 84.67  ? 484 ARG C CZ  1 
ATOM   11868 N NH1 . ARG C 1 424 ? -92.734  -11.799 -0.279  1.00 106.60 ? 484 ARG C NH1 1 
ATOM   11869 N NH2 . ARG C 1 424 ? -90.999  -12.670 0.928   1.00 91.50  ? 484 ARG C NH2 1 
ATOM   11870 N N   . PRO C 1 425 ? -92.850  -19.735 0.753   1.00 54.54  ? 485 PRO C N   1 
ATOM   11871 C CA  . PRO C 1 425 ? -92.511  -20.937 1.524   1.00 53.91  ? 485 PRO C CA  1 
ATOM   11872 C C   . PRO C 1 425 ? -91.456  -20.689 2.618   1.00 56.92  ? 485 PRO C C   1 
ATOM   11873 O O   . PRO C 1 425 ? -90.459  -20.029 2.393   1.00 61.75  ? 485 PRO C O   1 
ATOM   11874 C CB  . PRO C 1 425 ? -91.959  -21.937 0.491   1.00 60.08  ? 485 PRO C CB  1 
ATOM   11875 C CG  . PRO C 1 425 ? -91.484  -21.065 -0.666  1.00 64.70  ? 485 PRO C CG  1 
ATOM   11876 C CD  . PRO C 1 425 ? -92.334  -19.802 -0.618  1.00 60.84  ? 485 PRO C CD  1 
ATOM   11877 N N   . ILE C 1 426 ? -91.725  -21.202 3.815   1.00 61.42  ? 486 ILE C N   1 
ATOM   11878 C CA  . ILE C 1 426 ? -90.821  -21.116 4.992   1.00 60.12  ? 486 ILE C CA  1 
ATOM   11879 C C   . ILE C 1 426 ? -89.814  -22.264 4.879   1.00 57.89  ? 486 ILE C C   1 
ATOM   11880 O O   . ILE C 1 426 ? -90.209  -23.445 5.021   1.00 50.33  ? 486 ILE C O   1 
ATOM   11881 C CB  . ILE C 1 426 ? -91.638  -21.096 6.298   1.00 63.32  ? 486 ILE C CB  1 
ATOM   11882 C CG1 . ILE C 1 426 ? -92.304  -19.732 6.493   1.00 62.14  ? 486 ILE C CG1 1 
ATOM   11883 C CG2 . ILE C 1 426 ? -90.782  -21.419 7.497   1.00 67.16  ? 486 ILE C CG2 1 
ATOM   11884 C CD1 . ILE C 1 426 ? -93.728  -19.681 6.081   1.00 61.88  ? 486 ILE C CD1 1 
ATOM   11885 N N   . ILE C 1 427 ? -88.559  -21.903 4.586   1.00 61.00  ? 487 ILE C N   1 
ATOM   11886 C CA  . ILE C 1 427 ? -87.403  -22.848 4.520   1.00 63.50  ? 487 ILE C CA  1 
ATOM   11887 C C   . ILE C 1 427 ? -86.426  -22.495 5.647   1.00 52.24  ? 487 ILE C C   1 
ATOM   11888 O O   . ILE C 1 427 ? -85.952  -21.324 5.698   1.00 47.18  ? 487 ILE C O   1 
ATOM   11889 C CB  . ILE C 1 427 ? -86.703  -22.837 3.143   1.00 74.45  ? 487 ILE C CB  1 
ATOM   11890 C CG1 . ILE C 1 427 ? -87.689  -22.790 1.967   1.00 68.75  ? 487 ILE C CG1 1 
ATOM   11891 C CG2 . ILE C 1 427 ? -85.721  -24.011 3.030   1.00 71.75  ? 487 ILE C CG2 1 
ATOM   11892 C CD1 . ILE C 1 427 ? -88.578  -23.993 1.857   1.00 70.11  ? 487 ILE C CD1 1 
ATOM   11893 N N   . PHE C 1 428 ? -86.176  -23.492 6.494   1.00 44.51  ? 488 PHE C N   1 
ATOM   11894 C CA  . PHE C 1 428 ? -85.307  -23.460 7.690   1.00 47.44  ? 488 PHE C CA  1 
ATOM   11895 C C   . PHE C 1 428 ? -84.220  -24.516 7.500   1.00 53.49  ? 488 PHE C C   1 
ATOM   11896 O O   . PHE C 1 428 ? -84.505  -25.749 7.568   1.00 54.58  ? 488 PHE C O   1 
ATOM   11897 C CB  . PHE C 1 428 ? -86.133  -23.708 8.957   1.00 50.97  ? 488 PHE C CB  1 
ATOM   11898 C CG  . PHE C 1 428 ? -86.748  -22.476 9.577   1.00 56.87  ? 488 PHE C CG  1 
ATOM   11899 C CD1 . PHE C 1 428 ? -86.923  -21.305 8.861   1.00 62.72  ? 488 PHE C CD1 1 
ATOM   11900 C CD2 . PHE C 1 428 ? -87.169  -22.483 10.891  1.00 61.82  ? 488 PHE C CD2 1 
ATOM   11901 C CE1 . PHE C 1 428 ? -87.514  -20.188 9.433   1.00 63.68  ? 488 PHE C CE1 1 
ATOM   11902 C CE2 . PHE C 1 428 ? -87.732  -21.352 11.465  1.00 62.31  ? 488 PHE C CE2 1 
ATOM   11903 C CZ  . PHE C 1 428 ? -87.918  -20.212 10.736  1.00 59.60  ? 488 PHE C CZ  1 
ATOM   11904 N N   . SER C 1 429 ? -83.000  -24.034 7.230   1.00 55.80  ? 489 SER C N   1 
ATOM   11905 C CA  . SER C 1 429 ? -81.786  -24.853 7.000   1.00 56.37  ? 489 SER C CA  1 
ATOM   11906 C C   . SER C 1 429 ? -80.915  -24.801 8.260   1.00 57.78  ? 489 SER C C   1 
ATOM   11907 O O   . SER C 1 429 ? -80.078  -23.900 8.394   1.00 54.91  ? 489 SER C O   1 
ATOM   11908 C CB  . SER C 1 429 ? -81.090  -24.380 5.773   1.00 53.72  ? 489 SER C CB  1 
ATOM   11909 O OG  . SER C 1 429 ? -80.083  -25.295 5.408   1.00 61.35  ? 489 SER C OG  1 
ATOM   11910 N N   . LEU C 1 430 ? -81.146  -25.729 9.180   1.00 62.58  ? 490 LEU C N   1 
ATOM   11911 C CA  . LEU C 1 430 ? -80.710  -25.579 10.589  1.00 64.51  ? 490 LEU C CA  1 
ATOM   11912 C C   . LEU C 1 430 ? -79.297  -26.144 10.770  1.00 65.03  ? 490 LEU C C   1 
ATOM   11913 O O   . LEU C 1 430 ? -78.558  -25.590 11.584  1.00 65.64  ? 490 LEU C O   1 
ATOM   11914 C CB  . LEU C 1 430 ? -81.708  -26.308 11.499  1.00 72.01  ? 490 LEU C CB  1 
ATOM   11915 C CG  . LEU C 1 430 ? -83.001  -25.581 11.894  1.00 75.01  ? 490 LEU C CG  1 
ATOM   11916 C CD1 . LEU C 1 430 ? -83.001  -25.255 13.368  1.00 91.68  ? 490 LEU C CD1 1 
ATOM   11917 C CD2 . LEU C 1 430 ? -83.258  -24.306 11.117  1.00 78.56  ? 490 LEU C CD2 1 
ATOM   11918 N N   . SER C 1 431 ? -78.926  -27.207 10.051  1.00 62.79  ? 491 SER C N   1 
ATOM   11919 C CA  . SER C 1 431 ? -77.643  -27.929 10.272  1.00 58.44  ? 491 SER C CA  1 
ATOM   11920 C C   . SER C 1 431 ? -76.453  -26.954 10.232  1.00 61.89  ? 491 SER C C   1 
ATOM   11921 O O   . SER C 1 431 ? -76.553  -25.908 9.545   1.00 61.98  ? 491 SER C O   1 
ATOM   11922 C CB  . SER C 1 431 ? -77.483  -29.058 9.313   1.00 51.81  ? 491 SER C CB  1 
ATOM   11923 O OG  . SER C 1 431 ? -78.448  -30.060 9.608   1.00 52.71  ? 491 SER C OG  1 
ATOM   11924 N N   . ASN C 1 432 ? -75.392  -27.293 10.975  1.00 72.11  ? 492 ASN C N   1 
ATOM   11925 C CA  . ASN C 1 432 ? -74.113  -26.532 11.117  1.00 63.15  ? 492 ASN C CA  1 
ATOM   11926 C C   . ASN C 1 432 ? -72.931  -27.492 10.995  1.00 58.41  ? 492 ASN C C   1 
ATOM   11927 O O   . ASN C 1 432 ? -73.036  -28.692 11.272  1.00 54.63  ? 492 ASN C O   1 
ATOM   11928 C CB  . ASN C 1 432 ? -74.028  -25.820 12.475  1.00 70.90  ? 492 ASN C CB  1 
ATOM   11929 C CG  . ASN C 1 432 ? -75.135  -24.814 12.688  1.00 61.37  ? 492 ASN C CG  1 
ATOM   11930 O OD1 . ASN C 1 432 ? -75.331  -23.970 11.830  1.00 68.51  ? 492 ASN C OD1 1 
ATOM   11931 N ND2 . ASN C 1 432 ? -75.855  -24.910 13.798  1.00 47.58  ? 492 ASN C ND2 1 
ATOM   11932 N N   . PRO C 1 433 ? -71.743  -27.008 10.594  1.00 59.25  ? 493 PRO C N   1 
ATOM   11933 C CA  . PRO C 1 433 ? -71.528  -25.606 10.249  1.00 59.59  ? 493 PRO C CA  1 
ATOM   11934 C C   . PRO C 1 433 ? -71.980  -25.345 8.802   1.00 69.47  ? 493 PRO C C   1 
ATOM   11935 O O   . PRO C 1 433 ? -72.706  -26.172 8.268   1.00 66.90  ? 493 PRO C O   1 
ATOM   11936 C CB  . PRO C 1 433 ? -70.005  -25.451 10.438  1.00 55.79  ? 493 PRO C CB  1 
ATOM   11937 C CG  . PRO C 1 433 ? -69.458  -26.820 10.052  1.00 54.77  ? 493 PRO C CG  1 
ATOM   11938 C CD  . PRO C 1 433 ? -70.527  -27.817 10.442  1.00 57.62  ? 493 PRO C CD  1 
ATOM   11939 N N   . THR C 1 434 ? -71.528  -24.228 8.195   1.00 66.39  ? 494 THR C N   1 
ATOM   11940 C CA  . THR C 1 434 ? -71.986  -23.708 6.875   1.00 55.19  ? 494 THR C CA  1 
ATOM   11941 C C   . THR C 1 434 ? -71.919  -24.828 5.836   1.00 50.63  ? 494 THR C C   1 
ATOM   11942 O O   . THR C 1 434 ? -72.880  -25.015 5.108   1.00 50.24  ? 494 THR C O   1 
ATOM   11943 C CB  . THR C 1 434 ? -71.169  -22.476 6.464   1.00 58.32  ? 494 THR C CB  1 
ATOM   11944 O OG1 . THR C 1 434 ? -71.136  -21.546 7.550   1.00 54.17  ? 494 THR C OG1 1 
ATOM   11945 C CG2 . THR C 1 434 ? -71.720  -21.782 5.241   1.00 55.97  ? 494 THR C CG2 1 
ATOM   11946 N N   . SER C 1 435 ? -70.818  -25.568 5.808   1.00 52.05  ? 495 SER C N   1 
ATOM   11947 C CA  . SER C 1 435 ? -70.566  -26.707 4.889   1.00 57.04  ? 495 SER C CA  1 
ATOM   11948 C C   . SER C 1 435 ? -71.634  -27.804 5.006   1.00 54.39  ? 495 SER C C   1 
ATOM   11949 O O   . SER C 1 435 ? -71.754  -28.590 4.066   1.00 57.03  ? 495 SER C O   1 
ATOM   11950 C CB  . SER C 1 435 ? -69.220  -27.285 5.159   1.00 56.20  ? 495 SER C CB  1 
ATOM   11951 O OG  . SER C 1 435 ? -69.270  -27.960 6.399   1.00 57.40  ? 495 SER C OG  1 
ATOM   11952 N N   . HIS C 1 436 ? -72.360  -27.896 6.113   1.00 57.63  ? 496 HIS C N   1 
ATOM   11953 C CA  . HIS C 1 436 ? -73.427  -28.919 6.292   1.00 61.13  ? 496 HIS C CA  1 
ATOM   11954 C C   . HIS C 1 436 ? -74.846  -28.317 6.191   1.00 58.02  ? 496 HIS C C   1 
ATOM   11955 O O   . HIS C 1 436 ? -75.815  -29.102 6.293   1.00 54.40  ? 496 HIS C O   1 
ATOM   11956 C CB  . HIS C 1 436 ? -73.190  -29.681 7.595   1.00 57.37  ? 496 HIS C CB  1 
ATOM   11957 C CG  . HIS C 1 436 ? -72.084  -30.653 7.482   1.00 55.27  ? 496 HIS C CG  1 
ATOM   11958 N ND1 . HIS C 1 436 ? -72.294  -32.002 7.299   1.00 64.53  ? 496 HIS C ND1 1 
ATOM   11959 C CD2 . HIS C 1 436 ? -70.760  -30.457 7.474   1.00 51.38  ? 496 HIS C CD2 1 
ATOM   11960 C CE1 . HIS C 1 436 ? -71.134  -32.614 7.247   1.00 61.71  ? 496 HIS C CE1 1 
ATOM   11961 N NE2 . HIS C 1 436 ? -70.182  -31.680 7.332   1.00 55.95  ? 496 HIS C NE2 1 
ATOM   11962 N N   . SER C 1 437 ? -74.976  -27.002 5.979   1.00 55.29  ? 497 SER C N   1 
ATOM   11963 C CA  . SER C 1 437 ? -76.260  -26.301 5.698   1.00 54.31  ? 497 SER C CA  1 
ATOM   11964 C C   . SER C 1 437 ? -76.981  -27.058 4.570   1.00 49.40  ? 497 SER C C   1 
ATOM   11965 O O   . SER C 1 437 ? -76.357  -27.345 3.549   1.00 49.52  ? 497 SER C O   1 
ATOM   11966 C CB  . SER C 1 437 ? -76.008  -24.823 5.342   1.00 55.71  ? 497 SER C CB  1 
ATOM   11967 O OG  . SER C 1 437 ? -77.117  -23.987 5.656   1.00 55.35  ? 497 SER C OG  1 
ATOM   11968 N N   . GLU C 1 438 ? -78.263  -27.363 4.756   1.00 53.89  ? 498 GLU C N   1 
ATOM   11969 C CA  . GLU C 1 438 ? -79.124  -28.091 3.775   1.00 55.05  ? 498 GLU C CA  1 
ATOM   11970 C C   . GLU C 1 438 ? -79.261  -27.275 2.473   1.00 50.50  ? 498 GLU C C   1 
ATOM   11971 O O   . GLU C 1 438 ? -79.458  -27.883 1.392   1.00 47.25  ? 498 GLU C O   1 
ATOM   11972 C CB  . GLU C 1 438 ? -80.470  -28.419 4.431   1.00 57.55  ? 498 GLU C CB  1 
ATOM   11973 C CG  . GLU C 1 438 ? -80.397  -29.511 5.494   1.00 54.33  ? 498 GLU C CG  1 
ATOM   11974 C CD  . GLU C 1 438 ? -80.134  -29.098 6.941   1.00 58.29  ? 498 GLU C CD  1 
ATOM   11975 O OE1 . GLU C 1 438 ? -80.017  -27.849 7.238   1.00 54.23  ? 498 GLU C OE1 1 
ATOM   11976 O OE2 . GLU C 1 438 ? -80.075  -30.039 7.792   1.00 53.98  ? 498 GLU C OE2 1 
ATOM   11977 N N   . CYS C 1 439 ? -79.180  -25.948 2.567   1.00 47.36  ? 499 CYS C N   1 
ATOM   11978 C CA  . CYS C 1 439 ? -78.964  -25.053 1.408   1.00 46.56  ? 499 CYS C CA  1 
ATOM   11979 C C   . CYS C 1 439 ? -78.334  -23.773 1.917   1.00 44.54  ? 499 CYS C C   1 
ATOM   11980 O O   . CYS C 1 439 ? -78.264  -23.621 3.136   1.00 46.03  ? 499 CYS C O   1 
ATOM   11981 C CB  . CYS C 1 439 ? -80.243  -24.779 0.631   1.00 48.08  ? 499 CYS C CB  1 
ATOM   11982 S SG  . CYS C 1 439 ? -81.542  -23.886 1.523   1.00 57.56  ? 499 CYS C SG  1 
ATOM   11983 N N   . THR C 1 440 ? -77.800  -22.959 1.005   1.00 46.55  ? 500 THR C N   1 
ATOM   11984 C CA  . THR C 1 440 ? -77.261  -21.601 1.273   1.00 46.25  ? 500 THR C CA  1 
ATOM   11985 C C   . THR C 1 440 ? -78.431  -20.620 1.280   1.00 41.84  ? 500 THR C C   1 
ATOM   11986 O O   . THR C 1 440 ? -79.508  -20.987 0.797   1.00 36.45  ? 500 THR C O   1 
ATOM   11987 C CB  . THR C 1 440 ? -76.217  -21.184 0.227   1.00 55.90  ? 500 THR C CB  1 
ATOM   11988 O OG1 . THR C 1 440 ? -76.854  -20.736 -0.971  1.00 57.47  ? 500 THR C OG1 1 
ATOM   11989 C CG2 . THR C 1 440 ? -75.246  -22.292 -0.115  1.00 59.07  ? 500 THR C CG2 1 
ATOM   11990 N N   . ALA C 1 441 ? -78.204  -19.406 1.768   1.00 47.75  ? 501 ALA C N   1 
ATOM   11991 C CA  . ALA C 1 441 ? -79.129  -18.260 1.615   1.00 51.03  ? 501 ALA C CA  1 
ATOM   11992 C C   . ALA C 1 441 ? -79.240  -17.873 0.136   1.00 55.01  ? 501 ALA C C   1 
ATOM   11993 O O   . ALA C 1 441 ? -80.384  -17.574 -0.279  1.00 48.43  ? 501 ALA C O   1 
ATOM   11994 C CB  . ALA C 1 441 ? -78.674  -17.080 2.426   1.00 54.08  ? 501 ALA C CB  1 
ATOM   11995 N N   . GLU C 1 442 ? -78.128  -17.887 -0.621  1.00 56.49  ? 502 GLU C N   1 
ATOM   11996 C CA  . GLU C 1 442 ? -78.169  -17.553 -2.072  1.00 63.76  ? 502 GLU C CA  1 
ATOM   11997 C C   . GLU C 1 442 ? -79.074  -18.542 -2.824  1.00 67.61  ? 502 GLU C C   1 
ATOM   11998 O O   . GLU C 1 442 ? -79.862  -18.068 -3.641  1.00 71.54  ? 502 GLU C O   1 
ATOM   11999 C CB  . GLU C 1 442 ? -76.793  -17.515 -2.737  1.00 78.98  ? 502 GLU C CB  1 
ATOM   12000 C CG  . GLU C 1 442 ? -76.148  -16.126 -2.730  1.00 109.18 ? 502 GLU C CG  1 
ATOM   12001 C CD  . GLU C 1 442 ? -76.291  -15.230 -3.964  1.00 111.41 ? 502 GLU C CD  1 
ATOM   12002 O OE1 . GLU C 1 442 ? -76.282  -13.966 -3.814  1.00 98.98  ? 502 GLU C OE1 1 
ATOM   12003 O OE2 . GLU C 1 442 ? -76.361  -15.782 -5.082  1.00 118.58 ? 502 GLU C OE2 1 
ATOM   12004 N N   . GLN C 1 443 ? -78.988  -19.854 -2.559  1.00 67.07  ? 503 GLN C N   1 
ATOM   12005 C CA  . GLN C 1 443 ? -79.747  -20.909 -3.293  1.00 58.68  ? 503 GLN C CA  1 
ATOM   12006 C C   . GLN C 1 443 ? -81.249  -20.718 -3.054  1.00 61.10  ? 503 GLN C C   1 
ATOM   12007 O O   . GLN C 1 443 ? -82.015  -20.730 -4.047  1.00 74.61  ? 503 GLN C O   1 
ATOM   12008 C CB  . GLN C 1 443 ? -79.292  -22.304 -2.848  1.00 55.39  ? 503 GLN C CB  1 
ATOM   12009 C CG  . GLN C 1 443 ? -77.864  -22.646 -3.256  1.00 53.31  ? 503 GLN C CG  1 
ATOM   12010 C CD  . GLN C 1 443 ? -77.363  -23.920 -2.625  1.00 57.87  ? 503 GLN C CD  1 
ATOM   12011 O OE1 . GLN C 1 443 ? -77.907  -24.433 -1.661  1.00 72.98  ? 503 GLN C OE1 1 
ATOM   12012 N NE2 . GLN C 1 443 ? -76.295  -24.462 -3.160  1.00 68.71  ? 503 GLN C NE2 1 
ATOM   12013 N N   . ALA C 1 444 ? -81.641  -20.541 -1.786  1.00 63.30  ? 504 ALA C N   1 
ATOM   12014 C CA  . ALA C 1 444 ? -83.038  -20.460 -1.302  1.00 65.33  ? 504 ALA C CA  1 
ATOM   12015 C C   . ALA C 1 444 ? -83.756  -19.258 -1.916  1.00 65.52  ? 504 ALA C C   1 
ATOM   12016 O O   . ALA C 1 444 ? -84.906  -19.441 -2.301  1.00 71.12  ? 504 ALA C O   1 
ATOM   12017 C CB  . ALA C 1 444 ? -83.061  -20.359 0.200   1.00 72.90  ? 504 ALA C CB  1 
ATOM   12018 N N   . TYR C 1 445 ? -83.133  -18.073 -1.944  1.00 64.78  ? 505 TYR C N   1 
ATOM   12019 C CA  . TYR C 1 445 ? -83.707  -16.838 -2.559  1.00 70.02  ? 505 TYR C CA  1 
ATOM   12020 C C   . TYR C 1 445 ? -83.698  -16.902 -4.103  1.00 67.46  ? 505 TYR C C   1 
ATOM   12021 O O   . TYR C 1 445 ? -84.653  -16.390 -4.739  1.00 55.73  ? 505 TYR C O   1 
ATOM   12022 C CB  . TYR C 1 445 ? -83.026  -15.560 -2.046  1.00 69.09  ? 505 TYR C CB  1 
ATOM   12023 C CG  . TYR C 1 445 ? -83.276  -15.246 -0.591  1.00 66.18  ? 505 TYR C CG  1 
ATOM   12024 C CD1 . TYR C 1 445 ? -84.552  -15.055 -0.115  1.00 62.06  ? 505 TYR C CD1 1 
ATOM   12025 C CD2 . TYR C 1 445 ? -82.237  -15.156 0.320   1.00 71.43  ? 505 TYR C CD2 1 
ATOM   12026 C CE1 . TYR C 1 445 ? -84.792  -14.814 1.227   1.00 67.76  ? 505 TYR C CE1 1 
ATOM   12027 C CE2 . TYR C 1 445 ? -82.460  -14.885 1.661   1.00 71.53  ? 505 TYR C CE2 1 
ATOM   12028 C CZ  . TYR C 1 445 ? -83.747  -14.713 2.121   1.00 64.77  ? 505 TYR C CZ  1 
ATOM   12029 O OH  . TYR C 1 445 ? -83.978  -14.486 3.445   1.00 66.18  ? 505 TYR C OH  1 
ATOM   12030 N N   . THR C 1 446 ? -82.685  -17.501 -4.727  1.00 70.63  ? 506 THR C N   1 
ATOM   12031 C CA  . THR C 1 446 ? -82.633  -17.666 -6.211  1.00 72.93  ? 506 THR C CA  1 
ATOM   12032 C C   . THR C 1 446 ? -83.664  -18.714 -6.669  1.00 66.51  ? 506 THR C C   1 
ATOM   12033 O O   . THR C 1 446 ? -84.514  -18.346 -7.479  1.00 75.52  ? 506 THR C O   1 
ATOM   12034 C CB  . THR C 1 446 ? -81.216  -18.001 -6.677  1.00 75.08  ? 506 THR C CB  1 
ATOM   12035 O OG1 . THR C 1 446 ? -80.345  -17.160 -5.926  1.00 94.93  ? 506 THR C OG1 1 
ATOM   12036 C CG2 . THR C 1 446 ? -80.993  -17.715 -8.143  1.00 71.11  ? 506 THR C CG2 1 
ATOM   12037 N N   . TRP C 1 447 ? -83.634  -19.931 -6.129  1.00 58.15  ? 507 TRP C N   1 
ATOM   12038 C CA  . TRP C 1 447 ? -84.477  -21.083 -6.560  1.00 64.33  ? 507 TRP C CA  1 
ATOM   12039 C C   . TRP C 1 447 ? -85.967  -20.892 -6.195  1.00 71.61  ? 507 TRP C C   1 
ATOM   12040 O O   . TRP C 1 447 ? -86.825  -21.729 -6.618  1.00 63.96  ? 507 TRP C O   1 
ATOM   12041 C CB  . TRP C 1 447 ? -83.917  -22.385 -5.965  1.00 64.58  ? 507 TRP C CB  1 
ATOM   12042 C CG  . TRP C 1 447 ? -82.527  -22.712 -6.407  1.00 62.23  ? 507 TRP C CG  1 
ATOM   12043 C CD1 . TRP C 1 447 ? -81.881  -22.225 -7.503  1.00 62.21  ? 507 TRP C CD1 1 
ATOM   12044 C CD2 . TRP C 1 447 ? -81.614  -23.632 -5.778  1.00 73.87  ? 507 TRP C CD2 1 
ATOM   12045 N NE1 . TRP C 1 447 ? -80.639  -22.792 -7.617  1.00 60.12  ? 507 TRP C NE1 1 
ATOM   12046 C CE2 . TRP C 1 447 ? -80.439  -23.646 -6.565  1.00 65.65  ? 507 TRP C CE2 1 
ATOM   12047 C CE3 . TRP C 1 447 ? -81.665  -24.443 -4.627  1.00 88.08  ? 507 TRP C CE3 1 
ATOM   12048 C CZ2 . TRP C 1 447 ? -79.335  -24.437 -6.238  1.00 72.96  ? 507 TRP C CZ2 1 
ATOM   12049 C CZ3 . TRP C 1 447 ? -80.570  -25.226 -4.300  1.00 87.61  ? 507 TRP C CZ3 1 
ATOM   12050 C CH2 . TRP C 1 447 ? -79.421  -25.219 -5.099  1.00 90.63  ? 507 TRP C CH2 1 
ATOM   12051 N N   . SER C 1 448 ? -86.281  -19.850 -5.420  1.00 66.96  ? 508 SER C N   1 
ATOM   12052 C CA  . SER C 1 448 ? -87.662  -19.509 -4.994  1.00 60.08  ? 508 SER C CA  1 
ATOM   12053 C C   . SER C 1 448 ? -88.085  -18.152 -5.541  1.00 54.82  ? 508 SER C C   1 
ATOM   12054 O O   . SER C 1 448 ? -89.056  -17.646 -5.024  1.00 52.89  ? 508 SER C O   1 
ATOM   12055 C CB  . SER C 1 448 ? -87.769  -19.461 -3.501  1.00 68.19  ? 508 SER C CB  1 
ATOM   12056 O OG  . SER C 1 448 ? -87.356  -18.186 -3.028  1.00 63.03  ? 508 SER C OG  1 
ATOM   12057 N N   . GLN C 1 449 ? -87.333  -17.568 -6.477  1.00 63.99  ? 509 GLN C N   1 
ATOM   12058 C CA  . GLN C 1 449 ? -87.597  -16.240 -7.118  1.00 66.37  ? 509 GLN C CA  1 
ATOM   12059 C C   . GLN C 1 449 ? -87.825  -15.146 -6.048  1.00 63.36  ? 509 GLN C C   1 
ATOM   12060 O O   . GLN C 1 449 ? -88.698  -14.282 -6.245  1.00 59.90  ? 509 GLN C O   1 
ATOM   12061 C CB  . GLN C 1 449 ? -88.771  -16.400 -8.097  1.00 73.81  ? 509 GLN C CB  1 
ATOM   12062 C CG  . GLN C 1 449 ? -88.451  -17.320 -9.277  1.00 77.76  ? 509 GLN C CG  1 
ATOM   12063 C CD  . GLN C 1 449 ? -89.669  -17.989 -9.866  1.00 80.86  ? 509 GLN C CD  1 
ATOM   12064 O OE1 . GLN C 1 449 ? -90.806  -17.547 -9.680  1.00 83.09  ? 509 GLN C OE1 1 
ATOM   12065 N NE2 . GLN C 1 449 ? -89.428  -19.094 -10.555 1.00 72.92  ? 509 GLN C NE2 1 
ATOM   12066 N N   . GLY C 1 450 ? -87.044  -15.159 -4.967  1.00 60.93  ? 510 GLY C N   1 
ATOM   12067 C CA  . GLY C 1 450 ? -87.051  -14.116 -3.918  1.00 64.16  ? 510 GLY C CA  1 
ATOM   12068 C C   . GLY C 1 450 ? -88.261  -14.194 -3.005  1.00 64.78  ? 510 GLY C C   1 
ATOM   12069 O O   . GLY C 1 450 ? -88.527  -13.197 -2.306  1.00 65.99  ? 510 GLY C O   1 
ATOM   12070 N N   . ARG C 1 451 ? -88.951  -15.336 -2.971  1.00 61.80  ? 511 ARG C N   1 
ATOM   12071 C CA  . ARG C 1 451 ? -90.293  -15.443 -2.333  1.00 63.77  ? 511 ARG C CA  1 
ATOM   12072 C C   . ARG C 1 451 ? -90.220  -16.261 -1.034  1.00 62.93  ? 511 ARG C C   1 
ATOM   12073 O O   . ARG C 1 451 ? -91.198  -16.213 -0.277  1.00 65.36  ? 511 ARG C O   1 
ATOM   12074 C CB  . ARG C 1 451 ? -91.308  -16.052 -3.311  1.00 59.50  ? 511 ARG C CB  1 
ATOM   12075 C CG  . ARG C 1 451 ? -91.767  -15.156 -4.451  1.00 50.43  ? 511 ARG C CG  1 
ATOM   12076 C CD  . ARG C 1 451 ? -92.935  -15.768 -5.217  1.00 53.44  ? 511 ARG C CD  1 
ATOM   12077 N NE  . ARG C 1 451 ? -92.665  -16.944 -6.050  1.00 59.37  ? 511 ARG C NE  1 
ATOM   12078 C CZ  . ARG C 1 451 ? -92.856  -18.237 -5.706  1.00 63.54  ? 511 ARG C CZ  1 
ATOM   12079 N NH1 . ARG C 1 451 ? -93.322  -18.606 -4.521  1.00 64.49  ? 511 ARG C NH1 1 
ATOM   12080 N NH2 . ARG C 1 451 ? -92.572  -19.187 -6.583  1.00 66.16  ? 511 ARG C NH2 1 
ATOM   12081 N N   . SER C 1 452 ? -89.127  -16.986 -0.776  1.00 64.55  ? 512 SER C N   1 
ATOM   12082 C CA  . SER C 1 452 ? -88.948  -17.796 0.461   1.00 64.02  ? 512 SER C CA  1 
ATOM   12083 C C   . SER C 1 452 ? -88.690  -16.878 1.670   1.00 58.77  ? 512 SER C C   1 
ATOM   12084 O O   . SER C 1 452 ? -88.078  -15.813 1.506   1.00 52.27  ? 512 SER C O   1 
ATOM   12085 C CB  . SER C 1 452 ? -87.856  -18.820 0.318   1.00 57.34  ? 512 SER C CB  1 
ATOM   12086 O OG  . SER C 1 452 ? -86.597  -18.173 0.215   1.00 59.92  ? 512 SER C OG  1 
ATOM   12087 N N   . ILE C 1 453 ? -89.235  -17.275 2.820   1.00 57.85  ? 513 ILE C N   1 
ATOM   12088 C CA  . ILE C 1 453 ? -88.814  -16.834 4.175   1.00 56.88  ? 513 ILE C CA  1 
ATOM   12089 C C   . ILE C 1 453 ? -87.775  -17.858 4.644   1.00 59.78  ? 513 ILE C C   1 
ATOM   12090 O O   . ILE C 1 453 ? -88.136  -19.032 4.955   1.00 56.04  ? 513 ILE C O   1 
ATOM   12091 C CB  . ILE C 1 453 ? -90.025  -16.691 5.124   1.00 63.84  ? 513 ILE C CB  1 
ATOM   12092 C CG1 . ILE C 1 453 ? -90.848  -15.410 4.916   1.00 61.15  ? 513 ILE C CG1 1 
ATOM   12093 C CG2 . ILE C 1 453 ? -89.599  -16.714 6.586   1.00 60.37  ? 513 ILE C CG2 1 
ATOM   12094 C CD1 . ILE C 1 453 ? -90.881  -14.819 3.552   1.00 59.54  ? 513 ILE C CD1 1 
ATOM   12095 N N   . PHE C 1 454 ? -86.515  -17.428 4.641   1.00 61.88  ? 514 PHE C N   1 
ATOM   12096 C CA  . PHE C 1 454 ? -85.336  -18.282 4.890   1.00 57.34  ? 514 PHE C CA  1 
ATOM   12097 C C   . PHE C 1 454 ? -84.672  -17.912 6.213   1.00 58.20  ? 514 PHE C C   1 
ATOM   12098 O O   . PHE C 1 454 ? -84.494  -16.706 6.527   1.00 54.99  ? 514 PHE C O   1 
ATOM   12099 C CB  . PHE C 1 454 ? -84.306  -18.135 3.772   1.00 56.16  ? 514 PHE C CB  1 
ATOM   12100 C CG  . PHE C 1 454 ? -83.173  -19.107 3.929   1.00 57.45  ? 514 PHE C CG  1 
ATOM   12101 C CD1 . PHE C 1 454 ? -83.398  -20.484 3.863   1.00 54.69  ? 514 PHE C CD1 1 
ATOM   12102 C CD2 . PHE C 1 454 ? -81.905  -18.643 4.242   1.00 59.30  ? 514 PHE C CD2 1 
ATOM   12103 C CE1 . PHE C 1 454 ? -82.358  -21.382 4.049   1.00 55.03  ? 514 PHE C CE1 1 
ATOM   12104 C CE2 . PHE C 1 454 ? -80.868  -19.542 4.429   1.00 59.97  ? 514 PHE C CE2 1 
ATOM   12105 C CZ  . PHE C 1 454 ? -81.099  -20.906 4.332   1.00 60.04  ? 514 PHE C CZ  1 
ATOM   12106 N N   . ALA C 1 455 ? -84.274  -18.947 6.947   1.00 54.61  ? 515 ALA C N   1 
ATOM   12107 C CA  . ALA C 1 455 ? -83.354  -18.839 8.090   1.00 51.79  ? 515 ALA C CA  1 
ATOM   12108 C C   . ALA C 1 455 ? -82.561  -20.149 8.221   1.00 50.32  ? 515 ALA C C   1 
ATOM   12109 O O   . ALA C 1 455 ? -83.044  -21.182 7.722   1.00 52.27  ? 515 ALA C O   1 
ATOM   12110 C CB  . ALA C 1 455 ? -84.151  -18.516 9.304   1.00 54.94  ? 515 ALA C CB  1 
ATOM   12111 N N   . SER C 1 456 ? -81.367  -20.081 8.817   1.00 46.87  ? 516 SER C N   1 
ATOM   12112 C CA  . SER C 1 456 ? -80.362  -21.167 8.868   1.00 45.94  ? 516 SER C CA  1 
ATOM   12113 C C   . SER C 1 456 ? -79.607  -21.126 10.192  1.00 47.39  ? 516 SER C C   1 
ATOM   12114 O O   . SER C 1 456 ? -79.633  -20.051 10.845  1.00 47.11  ? 516 SER C O   1 
ATOM   12115 C CB  . SER C 1 456 ? -79.385  -21.059 7.714   1.00 57.08  ? 516 SER C CB  1 
ATOM   12116 O OG  . SER C 1 456 ? -78.572  -19.888 7.800   1.00 60.43  ? 516 SER C OG  1 
ATOM   12117 N N   . GLY C 1 457 ? -78.915  -22.226 10.517  1.00 52.20  ? 517 GLY C N   1 
ATOM   12118 C CA  . GLY C 1 457 ? -78.109  -22.365 11.745  1.00 57.98  ? 517 GLY C CA  1 
ATOM   12119 C C   . GLY C 1 457 ? -76.841  -21.523 11.741  1.00 57.94  ? 517 GLY C C   1 
ATOM   12120 O O   . GLY C 1 457 ? -76.458  -20.950 12.802  1.00 44.95  ? 517 GLY C O   1 
ATOM   12121 N N   . SER C 1 458 ? -76.146  -21.508 10.604  1.00 66.06  ? 518 SER C N   1 
ATOM   12122 C CA  . SER C 1 458 ? -74.820  -20.848 10.464  1.00 70.50  ? 518 SER C CA  1 
ATOM   12123 C C   . SER C 1 458 ? -75.001  -19.541 9.697   1.00 63.51  ? 518 SER C C   1 
ATOM   12124 O O   . SER C 1 458 ? -75.857  -19.477 8.824   1.00 58.64  ? 518 SER C O   1 
ATOM   12125 C CB  . SER C 1 458 ? -73.872  -21.791 9.810   1.00 67.27  ? 518 SER C CB  1 
ATOM   12126 O OG  . SER C 1 458 ? -74.433  -23.096 9.750   1.00 80.20  ? 518 SER C OG  1 
ATOM   12127 N N   . PRO C 1 459 ? -74.226  -18.469 9.974   1.00 56.95  ? 519 PRO C N   1 
ATOM   12128 C CA  . PRO C 1 459 ? -74.494  -17.159 9.385   1.00 62.64  ? 519 PRO C CA  1 
ATOM   12129 C C   . PRO C 1 459 ? -74.185  -17.167 7.884   1.00 63.53  ? 519 PRO C C   1 
ATOM   12130 O O   . PRO C 1 459 ? -73.288  -17.897 7.508   1.00 75.72  ? 519 PRO C O   1 
ATOM   12131 C CB  . PRO C 1 459 ? -73.554  -16.201 10.115  1.00 62.23  ? 519 PRO C CB  1 
ATOM   12132 C CG  . PRO C 1 459 ? -72.423  -17.101 10.508  1.00 69.04  ? 519 PRO C CG  1 
ATOM   12133 C CD  . PRO C 1 459 ? -73.033  -18.458 10.811  1.00 59.95  ? 519 PRO C CD  1 
ATOM   12134 N N   . PHE C 1 460 ? -74.978  -16.423 7.092   1.00 62.52  ? 520 PHE C N   1 
ATOM   12135 C CA  . PHE C 1 460 ? -74.799  -16.149 5.639   1.00 53.33  ? 520 PHE C CA  1 
ATOM   12136 C C   . PHE C 1 460 ? -74.884  -14.641 5.417   1.00 51.93  ? 520 PHE C C   1 
ATOM   12137 O O   . PHE C 1 460 ? -75.726  -13.958 6.006   1.00 48.40  ? 520 PHE C O   1 
ATOM   12138 C CB  . PHE C 1 460 ? -75.874  -16.822 4.795   1.00 47.13  ? 520 PHE C CB  1 
ATOM   12139 C CG  . PHE C 1 460 ? -75.701  -18.309 4.638   1.00 49.88  ? 520 PHE C CG  1 
ATOM   12140 C CD1 . PHE C 1 460 ? -74.787  -18.811 3.739   1.00 54.78  ? 520 PHE C CD1 1 
ATOM   12141 C CD2 . PHE C 1 460 ? -76.460  -19.219 5.373   1.00 52.42  ? 520 PHE C CD2 1 
ATOM   12142 C CE1 . PHE C 1 460 ? -74.629  -20.186 3.576   1.00 58.39  ? 520 PHE C CE1 1 
ATOM   12143 C CE2 . PHE C 1 460 ? -76.315  -20.589 5.200   1.00 52.41  ? 520 PHE C CE2 1 
ATOM   12144 C CZ  . PHE C 1 460 ? -75.395  -21.077 4.298   1.00 53.45  ? 520 PHE C CZ  1 
ATOM   12145 N N   . ALA C 1 461 ? -74.010  -14.105 4.584   1.00 58.76  ? 521 ALA C N   1 
ATOM   12146 C CA  . ALA C 1 461 ? -74.000  -12.655 4.309   1.00 59.82  ? 521 ALA C CA  1 
ATOM   12147 C C   . ALA C 1 461 ? -75.308  -12.315 3.609   1.00 56.82  ? 521 ALA C C   1 
ATOM   12148 O O   . ALA C 1 461 ? -75.970  -13.210 3.054   1.00 46.30  ? 521 ALA C O   1 
ATOM   12149 C CB  . ALA C 1 461 ? -72.799  -12.299 3.472   1.00 65.20  ? 521 ALA C CB  1 
ATOM   12150 N N   . PRO C 1 462 ? -75.708  -11.020 3.625   1.00 52.74  ? 522 PRO C N   1 
ATOM   12151 C CA  . PRO C 1 462 ? -76.879  -10.570 2.870   1.00 55.89  ? 522 PRO C CA  1 
ATOM   12152 C C   . PRO C 1 462 ? -76.794  -11.050 1.415   1.00 57.81  ? 522 PRO C C   1 
ATOM   12153 O O   . PRO C 1 462 ? -75.694  -11.098 0.906   1.00 68.19  ? 522 PRO C O   1 
ATOM   12154 C CB  . PRO C 1 462 ? -76.829  -9.046  2.980   1.00 56.58  ? 522 PRO C CB  1 
ATOM   12155 C CG  . PRO C 1 462 ? -76.071  -8.791  4.262   1.00 58.16  ? 522 PRO C CG  1 
ATOM   12156 C CD  . PRO C 1 462 ? -75.081  -9.934  4.392   1.00 57.42  ? 522 PRO C CD  1 
ATOM   12157 N N   . VAL C 1 463 ? -77.933  -11.438 0.829   1.00 70.32  ? 523 VAL C N   1 
ATOM   12158 C CA  . VAL C 1 463 ? -78.071  -12.147 -0.485  1.00 72.65  ? 523 VAL C CA  1 
ATOM   12159 C C   . VAL C 1 463 ? -78.820  -11.172 -1.409  1.00 76.36  ? 523 VAL C C   1 
ATOM   12160 O O   . VAL C 1 463 ? -79.860  -10.625 -0.980  1.00 85.87  ? 523 VAL C O   1 
ATOM   12161 C CB  . VAL C 1 463 ? -78.763  -13.528 -0.316  1.00 64.74  ? 523 VAL C CB  1 
ATOM   12162 C CG1 . VAL C 1 463 ? -79.316  -14.102 -1.595  1.00 58.53  ? 523 VAL C CG1 1 
ATOM   12163 C CG2 . VAL C 1 463 ? -77.814  -14.541 0.314   1.00 72.16  ? 523 VAL C CG2 1 
ATOM   12164 N N   . GLU C 1 464 ? -78.247  -10.866 -2.577  1.00 83.28  ? 524 GLU C N   1 
ATOM   12165 C CA  . GLU C 1 464 ? -78.876  -9.930  -3.556  1.00 85.13  ? 524 GLU C CA  1 
ATOM   12166 C C   . GLU C 1 464 ? -79.488  -10.739 -4.708  1.00 88.98  ? 524 GLU C C   1 
ATOM   12167 O O   . GLU C 1 464 ? -78.813  -11.658 -5.224  1.00 83.82  ? 524 GLU C O   1 
ATOM   12168 C CB  . GLU C 1 464 ? -77.894  -8.866  -4.040  1.00 89.12  ? 524 GLU C CB  1 
ATOM   12169 C CG  . GLU C 1 464 ? -77.691  -7.757  -3.021  1.00 97.11  ? 524 GLU C CG  1 
ATOM   12170 C CD  . GLU C 1 464 ? -76.335  -7.061  -3.110  1.00 107.88 ? 524 GLU C CD  1 
ATOM   12171 O OE1 . GLU C 1 464 ? -75.783  -6.676  -2.042  1.00 96.65  ? 524 GLU C OE1 1 
ATOM   12172 O OE2 . GLU C 1 464 ? -75.819  -6.913  -4.248  1.00 99.16  ? 524 GLU C OE2 1 
ATOM   12173 N N   . TYR C 1 465 ? -80.758  -10.444 -5.019  1.00 88.03  ? 525 TYR C N   1 
ATOM   12174 C CA  . TYR C 1 465 ? -81.581  -11.072 -6.088  1.00 88.98  ? 525 TYR C CA  1 
ATOM   12175 C C   . TYR C 1 465 ? -82.503  -9.966  -6.640  1.00 80.28  ? 525 TYR C C   1 
ATOM   12176 O O   . TYR C 1 465 ? -83.324  -9.370  -5.872  1.00 85.48  ? 525 TYR C O   1 
ATOM   12177 C CB  . TYR C 1 465 ? -82.303  -12.323 -5.568  1.00 78.31  ? 525 TYR C CB  1 
ATOM   12178 C CG  . TYR C 1 465 ? -83.241  -12.941 -6.567  1.00 66.04  ? 525 TYR C CG  1 
ATOM   12179 C CD1 . TYR C 1 465 ? -82.796  -13.889 -7.478  1.00 67.42  ? 525 TYR C CD1 1 
ATOM   12180 C CD2 . TYR C 1 465 ? -84.566  -12.539 -6.626  1.00 67.36  ? 525 TYR C CD2 1 
ATOM   12181 C CE1 . TYR C 1 465 ? -83.652  -14.426 -8.428  1.00 72.20  ? 525 TYR C CE1 1 
ATOM   12182 C CE2 . TYR C 1 465 ? -85.435  -13.073 -7.567  1.00 78.55  ? 525 TYR C CE2 1 
ATOM   12183 C CZ  . TYR C 1 465 ? -84.967  -13.987 -8.497  1.00 74.62  ? 525 TYR C CZ  1 
ATOM   12184 O OH  . TYR C 1 465 ? -85.838  -14.489 -9.419  1.00 70.48  ? 525 TYR C OH  1 
ATOM   12185 N N   . GLU C 1 466 ? -82.348  -9.709  -7.946  1.00 65.62  ? 526 GLU C N   1 
ATOM   12186 C CA  . GLU C 1 466 ? -83.102  -8.692  -8.718  1.00 75.60  ? 526 GLU C CA  1 
ATOM   12187 C C   . GLU C 1 466 ? -83.082  -7.341  -7.981  1.00 73.43  ? 526 GLU C C   1 
ATOM   12188 O O   . GLU C 1 466 ? -84.154  -6.757  -7.786  1.00 75.89  ? 526 GLU C O   1 
ATOM   12189 C CB  . GLU C 1 466 ? -84.501  -9.236  -9.026  1.00 75.62  ? 526 GLU C CB  1 
ATOM   12190 C CG  . GLU C 1 466 ? -84.480  -10.089 -10.272 1.00 72.00  ? 526 GLU C CG  1 
ATOM   12191 C CD  . GLU C 1 466 ? -85.617  -11.060 -10.476 1.00 75.53  ? 526 GLU C CD  1 
ATOM   12192 O OE1 . GLU C 1 466 ? -86.701  -10.873 -9.882  1.00 84.14  ? 526 GLU C OE1 1 
ATOM   12193 O OE2 . GLU C 1 466 ? -85.399  -12.032 -11.219 1.00 73.41  ? 526 GLU C OE2 1 
ATOM   12194 N N   . GLY C 1 467 ? -81.893  -6.872  -7.598  1.00 73.72  ? 527 GLY C N   1 
ATOM   12195 C CA  . GLY C 1 467 ? -81.624  -5.472  -7.221  1.00 71.65  ? 527 GLY C CA  1 
ATOM   12196 C C   . GLY C 1 467 ? -82.176  -5.120  -5.862  1.00 68.79  ? 527 GLY C C   1 
ATOM   12197 O O   . GLY C 1 467 ? -82.301  -3.905  -5.586  1.00 67.27  ? 527 GLY C O   1 
ATOM   12198 N N   . LYS C 1 468 ? -82.463  -6.145  -5.050  1.00 72.59  ? 528 LYS C N   1 
ATOM   12199 C CA  . LYS C 1 468 ? -82.956  -6.015  -3.656  1.00 83.57  ? 528 LYS C CA  1 
ATOM   12200 C C   . LYS C 1 468 ? -82.041  -6.851  -2.733  1.00 85.61  ? 528 LYS C C   1 
ATOM   12201 O O   . LYS C 1 468 ? -81.490  -7.882  -3.223  1.00 100.85 ? 528 LYS C O   1 
ATOM   12202 C CB  . LYS C 1 468 ? -84.427  -6.451  -3.642  1.00 98.07  ? 528 LYS C CB  1 
ATOM   12203 C CG  . LYS C 1 468 ? -85.392  -5.563  -2.868  1.00 110.42 ? 528 LYS C CG  1 
ATOM   12204 C CD  . LYS C 1 468 ? -85.189  -5.627  -1.349  1.00 124.05 ? 528 LYS C CD  1 
ATOM   12205 C CE  . LYS C 1 468 ? -84.550  -4.377  -0.767  1.00 115.92 ? 528 LYS C CE  1 
ATOM   12206 N NZ  . LYS C 1 468 ? -84.194  -4.545  0.664   1.00 106.70 ? 528 LYS C NZ  1 
ATOM   12207 N N   . THR C 1 469 ? -81.935  -6.458  -1.449  1.00 74.17  ? 529 THR C N   1 
ATOM   12208 C CA  . THR C 1 469 ? -81.123  -7.116  -0.380  1.00 71.55  ? 529 THR C CA  1 
ATOM   12209 C C   . THR C 1 469 ? -82.012  -7.970  0.546   1.00 61.95  ? 529 THR C C   1 
ATOM   12210 O O   . THR C 1 469 ? -82.971  -7.434  1.097   1.00 61.20  ? 529 THR C O   1 
ATOM   12211 C CB  . THR C 1 469 ? -80.351  -6.051  0.421   1.00 66.27  ? 529 THR C CB  1 
ATOM   12212 O OG1 . THR C 1 469 ? -79.419  -5.441  -0.471  1.00 59.22  ? 529 THR C OG1 1 
ATOM   12213 C CG2 . THR C 1 469 ? -79.593  -6.566  1.628   1.00 63.51  ? 529 THR C CG2 1 
ATOM   12214 N N   . PHE C 1 470 ? -81.684  -9.255  0.709   1.00 60.74  ? 530 PHE C N   1 
ATOM   12215 C CA  . PHE C 1 470 ? -82.322  -10.186 1.686   1.00 67.77  ? 530 PHE C CA  1 
ATOM   12216 C C   . PHE C 1 470 ? -81.292  -10.491 2.793   1.00 74.93  ? 530 PHE C C   1 
ATOM   12217 O O   . PHE C 1 470 ? -80.203  -10.986 2.496   1.00 78.76  ? 530 PHE C O   1 
ATOM   12218 C CB  . PHE C 1 470 ? -82.864  -11.456 1.003   1.00 60.29  ? 530 PHE C CB  1 
ATOM   12219 C CG  . PHE C 1 470 ? -83.972  -11.196 0.021   1.00 62.69  ? 530 PHE C CG  1 
ATOM   12220 C CD1 . PHE C 1 470 ? -83.823  -10.289 -1.024  1.00 74.15  ? 530 PHE C CD1 1 
ATOM   12221 C CD2 . PHE C 1 470 ? -85.175  -11.859 0.117   1.00 67.55  ? 530 PHE C CD2 1 
ATOM   12222 C CE1 . PHE C 1 470 ? -84.851  -10.029 -1.914  1.00 77.77  ? 530 PHE C CE1 1 
ATOM   12223 C CE2 . PHE C 1 470 ? -86.199  -11.621 -0.788  1.00 72.06  ? 530 PHE C CE2 1 
ATOM   12224 C CZ  . PHE C 1 470 ? -86.040  -10.712 -1.803  1.00 74.96  ? 530 PHE C CZ  1 
ATOM   12225 N N   . VAL C 1 471 ? -81.618  -10.173 4.046   1.00 70.88  ? 531 VAL C N   1 
ATOM   12226 C CA  . VAL C 1 471 ? -80.795  -10.457 5.257   1.00 62.99  ? 531 VAL C CA  1 
ATOM   12227 C C   . VAL C 1 471 ? -81.346  -11.707 5.930   1.00 62.91  ? 531 VAL C C   1 
ATOM   12228 O O   . VAL C 1 471 ? -82.258  -11.608 6.738   1.00 76.38  ? 531 VAL C O   1 
ATOM   12229 C CB  . VAL C 1 471 ? -80.852  -9.266  6.223   1.00 61.55  ? 531 VAL C CB  1 
ATOM   12230 C CG1 . VAL C 1 471 ? -79.953  -9.529  7.414   1.00 60.36  ? 531 VAL C CG1 1 
ATOM   12231 C CG2 . VAL C 1 471 ? -80.499  -7.959  5.527   1.00 65.04  ? 531 VAL C CG2 1 
ATOM   12232 N N   . PRO C 1 472 ? -80.872  -12.925 5.613   1.00 56.93  ? 532 PRO C N   1 
ATOM   12233 C CA  . PRO C 1 472 ? -81.509  -14.133 6.129   1.00 57.67  ? 532 PRO C CA  1 
ATOM   12234 C C   . PRO C 1 472 ? -81.259  -14.177 7.634   1.00 55.52  ? 532 PRO C C   1 
ATOM   12235 O O   . PRO C 1 472 ? -80.187  -13.823 8.022   1.00 61.55  ? 532 PRO C O   1 
ATOM   12236 C CB  . PRO C 1 472 ? -80.827  -15.290 5.396   1.00 58.38  ? 532 PRO C CB  1 
ATOM   12237 C CG  . PRO C 1 472 ? -79.483  -14.708 5.014   1.00 63.95  ? 532 PRO C CG  1 
ATOM   12238 C CD  . PRO C 1 472 ? -79.700  -13.221 4.788   1.00 64.01  ? 532 PRO C CD  1 
ATOM   12239 N N   . GLY C 1 473 ? -82.266  -14.532 8.428   1.00 52.89  ? 533 GLY C N   1 
ATOM   12240 C CA  . GLY C 1 473 ? -82.104  -14.607 9.888   1.00 51.96  ? 533 GLY C CA  1 
ATOM   12241 C C   . GLY C 1 473 ? -81.289  -15.823 10.274  1.00 49.04  ? 533 GLY C C   1 
ATOM   12242 O O   . GLY C 1 473 ? -81.294  -16.809 9.465   1.00 35.85  ? 533 GLY C O   1 
ATOM   12243 N N   . GLN C 1 474 ? -80.665  -15.772 11.464  1.00 47.68  ? 534 GLN C N   1 
ATOM   12244 C CA  . GLN C 1 474 ? -79.936  -16.941 12.031  1.00 49.83  ? 534 GLN C CA  1 
ATOM   12245 C C   . GLN C 1 474 ? -80.793  -17.656 13.089  1.00 47.14  ? 534 GLN C C   1 
ATOM   12246 O O   . GLN C 1 474 ? -80.907  -17.186 14.233  1.00 43.73  ? 534 GLN C O   1 
ATOM   12247 C CB  . GLN C 1 474 ? -78.573  -16.544 12.587  1.00 56.48  ? 534 GLN C CB  1 
ATOM   12248 C CG  . GLN C 1 474 ? -77.553  -17.669 12.445  1.00 60.48  ? 534 GLN C CG  1 
ATOM   12249 C CD  . GLN C 1 474 ? -76.215  -17.344 13.045  1.00 58.08  ? 534 GLN C CD  1 
ATOM   12250 O OE1 . GLN C 1 474 ? -75.690  -18.146 13.800  1.00 58.59  ? 534 GLN C OE1 1 
ATOM   12251 N NE2 . GLN C 1 474 ? -75.711  -16.145 12.790  1.00 65.50  ? 534 GLN C NE2 1 
ATOM   12252 N N   . SER C 1 475 ? -81.378  -18.776 12.690  1.00 44.84  ? 535 SER C N   1 
ATOM   12253 C CA  . SER C 1 475 ? -82.214  -19.647 13.525  1.00 46.87  ? 535 SER C CA  1 
ATOM   12254 C C   . SER C 1 475 ? -81.274  -20.612 14.239  1.00 52.04  ? 535 SER C C   1 
ATOM   12255 O O   . SER C 1 475 ? -81.222  -21.806 13.847  1.00 51.51  ? 535 SER C O   1 
ATOM   12256 C CB  . SER C 1 475 ? -83.220  -20.327 12.673  1.00 48.67  ? 535 SER C CB  1 
ATOM   12257 O OG  . SER C 1 475 ? -83.765  -21.465 13.313  1.00 61.74  ? 535 SER C OG  1 
ATOM   12258 N N   . ASN C 1 476 ? -80.544  -20.078 15.224  1.00 54.49  ? 536 ASN C N   1 
ATOM   12259 C CA  . ASN C 1 476 ? -79.518  -20.782 16.045  1.00 65.56  ? 536 ASN C CA  1 
ATOM   12260 C C   . ASN C 1 476 ? -79.836  -20.546 17.533  1.00 69.11  ? 536 ASN C C   1 
ATOM   12261 O O   . ASN C 1 476 ? -80.185  -19.383 17.908  1.00 65.76  ? 536 ASN C O   1 
ATOM   12262 C CB  . ASN C 1 476 ? -78.100  -20.304 15.712  1.00 72.53  ? 536 ASN C CB  1 
ATOM   12263 C CG  . ASN C 1 476 ? -76.995  -21.148 16.320  1.00 73.75  ? 536 ASN C CG  1 
ATOM   12264 O OD1 . ASN C 1 476 ? -76.743  -21.078 17.522  1.00 66.53  ? 536 ASN C OD1 1 
ATOM   12265 N ND2 . ASN C 1 476 ? -76.291  -21.901 15.485  1.00 67.04  ? 536 ASN C ND2 1 
ATOM   12266 N N   . ASN C 1 477 ? -79.685  -21.585 18.365  1.00 57.67  ? 537 ASN C N   1 
ATOM   12267 C CA  . ASN C 1 477 ? -80.185  -21.575 19.761  1.00 55.90  ? 537 ASN C CA  1 
ATOM   12268 C C   . ASN C 1 477 ? -79.448  -20.508 20.590  1.00 49.15  ? 537 ASN C C   1 
ATOM   12269 O O   . ASN C 1 477 ? -79.859  -20.286 21.723  1.00 57.51  ? 537 ASN C O   1 
ATOM   12270 C CB  . ASN C 1 477 ? -80.140  -22.989 20.356  1.00 57.05  ? 537 ASN C CB  1 
ATOM   12271 C CG  . ASN C 1 477 ? -78.780  -23.623 20.269  1.00 54.23  ? 537 ASN C CG  1 
ATOM   12272 O OD1 . ASN C 1 477 ? -77.771  -22.945 20.424  1.00 53.09  ? 537 ASN C OD1 1 
ATOM   12273 N ND2 . ASN C 1 477 ? -78.757  -24.913 20.007  1.00 57.17  ? 537 ASN C ND2 1 
ATOM   12274 N N   . ALA C 1 478 ? -78.418  -19.865 20.046  1.00 47.45  ? 538 ALA C N   1 
ATOM   12275 C CA  . ALA C 1 478 ? -77.658  -18.738 20.648  1.00 48.68  ? 538 ALA C CA  1 
ATOM   12276 C C   . ALA C 1 478 ? -78.543  -17.518 20.931  1.00 47.84  ? 538 ALA C C   1 
ATOM   12277 O O   . ALA C 1 478 ? -78.130  -16.664 21.715  1.00 48.85  ? 538 ALA C O   1 
ATOM   12278 C CB  . ALA C 1 478 ? -76.550  -18.321 19.705  1.00 53.10  ? 538 ALA C CB  1 
ATOM   12279 N N   . TYR C 1 479 ? -79.683  -17.389 20.256  1.00 48.05  ? 539 TYR C N   1 
ATOM   12280 C CA  . TYR C 1 479 ? -80.698  -16.327 20.510  1.00 45.60  ? 539 TYR C CA  1 
ATOM   12281 C C   . TYR C 1 479 ? -81.515  -16.625 21.790  1.00 49.36  ? 539 TYR C C   1 
ATOM   12282 O O   . TYR C 1 479 ? -82.063  -15.686 22.385  1.00 49.55  ? 539 TYR C O   1 
ATOM   12283 C CB  . TYR C 1 479 ? -81.605  -16.246 19.280  1.00 45.54  ? 539 TYR C CB  1 
ATOM   12284 C CG  . TYR C 1 479 ? -81.258  -15.222 18.227  1.00 42.25  ? 539 TYR C CG  1 
ATOM   12285 C CD1 . TYR C 1 479 ? -81.400  -13.863 18.510  1.00 44.62  ? 539 TYR C CD1 1 
ATOM   12286 C CD2 . TYR C 1 479 ? -80.850  -15.588 16.945  1.00 36.10  ? 539 TYR C CD2 1 
ATOM   12287 C CE1 . TYR C 1 479 ? -81.117  -12.886 17.558  1.00 42.34  ? 539 TYR C CE1 1 
ATOM   12288 C CE2 . TYR C 1 479 ? -80.575  -14.622 15.978  1.00 40.07  ? 539 TYR C CE2 1 
ATOM   12289 C CZ  . TYR C 1 479 ? -80.704  -13.268 16.292  1.00 42.38  ? 539 TYR C CZ  1 
ATOM   12290 O OH  . TYR C 1 479 ? -80.443  -12.273 15.406  1.00 44.07  ? 539 TYR C OH  1 
ATOM   12291 N N   . ILE C 1 480 ? -81.590  -17.902 22.207  1.00 54.34  ? 540 ILE C N   1 
ATOM   12292 C CA  . ILE C 1 480 ? -82.511  -18.445 23.258  1.00 49.02  ? 540 ILE C CA  1 
ATOM   12293 C C   . ILE C 1 480 ? -81.713  -18.703 24.548  1.00 45.89  ? 540 ILE C C   1 
ATOM   12294 O O   . ILE C 1 480 ? -82.117  -18.134 25.571  1.00 57.42  ? 540 ILE C O   1 
ATOM   12295 C CB  . ILE C 1 480 ? -83.251  -19.731 22.763  1.00 51.59  ? 540 ILE C CB  1 
ATOM   12296 C CG1 . ILE C 1 480 ? -84.300  -19.448 21.678  1.00 48.49  ? 540 ILE C CG1 1 
ATOM   12297 C CG2 . ILE C 1 480 ? -83.861  -20.536 23.907  1.00 49.45  ? 540 ILE C CG2 1 
ATOM   12298 C CD1 . ILE C 1 480 ? -85.488  -18.665 22.116  1.00 44.94  ? 540 ILE C CD1 1 
ATOM   12299 N N   . PHE C 1 481 ? -80.672  -19.552 24.543  1.00 43.35  ? 541 PHE C N   1 
ATOM   12300 C CA  . PHE C 1 481 ? -80.107  -20.180 25.776  1.00 43.63  ? 541 PHE C CA  1 
ATOM   12301 C C   . PHE C 1 481 ? -79.485  -19.088 26.651  1.00 42.22  ? 541 PHE C C   1 
ATOM   12302 O O   . PHE C 1 481 ? -79.581  -19.189 27.866  1.00 45.85  ? 541 PHE C O   1 
ATOM   12303 C CB  . PHE C 1 481 ? -79.194  -21.395 25.499  1.00 43.01  ? 541 PHE C CB  1 
ATOM   12304 C CG  . PHE C 1 481 ? -77.840  -21.077 24.904  1.00 48.47  ? 541 PHE C CG  1 
ATOM   12305 C CD1 . PHE C 1 481 ? -76.876  -20.399 25.635  1.00 50.40  ? 541 PHE C CD1 1 
ATOM   12306 C CD2 . PHE C 1 481 ? -77.529  -21.410 23.590  1.00 53.91  ? 541 PHE C CD2 1 
ATOM   12307 C CE1 . PHE C 1 481 ? -75.654  -20.061 25.062  1.00 52.84  ? 541 PHE C CE1 1 
ATOM   12308 C CE2 . PHE C 1 481 ? -76.296  -21.088 23.027  1.00 50.39  ? 541 PHE C CE2 1 
ATOM   12309 C CZ  . PHE C 1 481 ? -75.352  -20.427 23.766  1.00 46.25  ? 541 PHE C CZ  1 
ATOM   12310 N N   . PRO C 1 482 ? -78.828  -18.024 26.127  1.00 38.99  ? 542 PRO C N   1 
ATOM   12311 C CA  . PRO C 1 482 ? -78.338  -16.940 26.974  1.00 40.62  ? 542 PRO C CA  1 
ATOM   12312 C C   . PRO C 1 482 ? -79.422  -16.312 27.840  1.00 39.38  ? 542 PRO C C   1 
ATOM   12313 O O   . PRO C 1 482 ? -79.192  -16.227 29.017  1.00 51.56  ? 542 PRO C O   1 
ATOM   12314 C CB  . PRO C 1 482 ? -77.787  -15.898 25.990  1.00 41.60  ? 542 PRO C CB  1 
ATOM   12315 C CG  . PRO C 1 482 ? -77.353  -16.757 24.833  1.00 39.40  ? 542 PRO C CG  1 
ATOM   12316 C CD  . PRO C 1 482 ? -78.435  -17.812 24.729  1.00 39.75  ? 542 PRO C CD  1 
ATOM   12317 N N   . GLY C 1 483 ? -80.542  -15.890 27.256  1.00 42.14  ? 543 GLY C N   1 
ATOM   12318 C CA  . GLY C 1 483 ? -81.713  -15.424 28.034  1.00 47.63  ? 543 GLY C CA  1 
ATOM   12319 C C   . GLY C 1 483 ? -82.340  -16.511 28.920  1.00 52.99  ? 543 GLY C C   1 
ATOM   12320 O O   . GLY C 1 483 ? -82.685  -16.202 30.075  1.00 49.88  ? 543 GLY C O   1 
ATOM   12321 N N   . LEU C 1 484 ? -82.515  -17.742 28.412  1.00 53.28  ? 544 LEU C N   1 
ATOM   12322 C CA  . LEU C 1 484 ? -83.205  -18.837 29.138  1.00 47.12  ? 544 LEU C CA  1 
ATOM   12323 C C   . LEU C 1 484 ? -82.362  -19.236 30.343  1.00 45.75  ? 544 LEU C C   1 
ATOM   12324 O O   . LEU C 1 484 ? -82.938  -19.495 31.407  1.00 48.87  ? 544 LEU C O   1 
ATOM   12325 C CB  . LEU C 1 484 ? -83.438  -20.025 28.206  1.00 50.27  ? 544 LEU C CB  1 
ATOM   12326 C CG  . LEU C 1 484 ? -84.004  -21.283 28.872  1.00 53.10  ? 544 LEU C CG  1 
ATOM   12327 C CD1 . LEU C 1 484 ? -85.263  -21.766 28.175  1.00 60.12  ? 544 LEU C CD1 1 
ATOM   12328 C CD2 . LEU C 1 484 ? -82.949  -22.395 28.937  1.00 57.89  ? 544 LEU C CD2 1 
ATOM   12329 N N   . GLY C 1 485 ? -81.045  -19.304 30.185  1.00 54.44  ? 545 GLY C N   1 
ATOM   12330 C CA  . GLY C 1 485 ? -80.115  -19.612 31.294  1.00 55.71  ? 545 GLY C CA  1 
ATOM   12331 C C   . GLY C 1 485 ? -80.183  -18.556 32.386  1.00 54.94  ? 545 GLY C C   1 
ATOM   12332 O O   . GLY C 1 485 ? -80.467  -18.948 33.542  1.00 55.11  ? 545 GLY C O   1 
ATOM   12333 N N   . LEU C 1 486 ? -79.965  -17.273 32.026  1.00 52.08  ? 546 LEU C N   1 
ATOM   12334 C CA  . LEU C 1 486 ? -80.021  -16.097 32.943  1.00 49.03  ? 546 LEU C CA  1 
ATOM   12335 C C   . LEU C 1 486 ? -81.342  -16.163 33.730  1.00 55.68  ? 546 LEU C C   1 
ATOM   12336 O O   . LEU C 1 486 ? -81.341  -15.910 34.959  1.00 50.63  ? 546 LEU C O   1 
ATOM   12337 C CB  . LEU C 1 486 ? -79.930  -14.793 32.151  1.00 43.13  ? 546 LEU C CB  1 
ATOM   12338 C CG  . LEU C 1 486 ? -80.055  -13.509 32.984  1.00 44.49  ? 546 LEU C CG  1 
ATOM   12339 C CD1 . LEU C 1 486 ? -78.866  -13.336 33.872  1.00 48.35  ? 546 LEU C CD1 1 
ATOM   12340 C CD2 . LEU C 1 486 ? -80.176  -12.265 32.134  1.00 48.70  ? 546 LEU C CD2 1 
ATOM   12341 N N   . GLY C 1 487 ? -82.427  -16.506 33.035  1.00 53.23  ? 547 GLY C N   1 
ATOM   12342 C CA  . GLY C 1 487 ? -83.767  -16.638 33.638  1.00 54.10  ? 547 GLY C CA  1 
ATOM   12343 C C   . GLY C 1 487 ? -83.826  -17.725 34.699  1.00 54.56  ? 547 GLY C C   1 
ATOM   12344 O O   . GLY C 1 487 ? -84.280  -17.411 35.807  1.00 62.44  ? 547 GLY C O   1 
ATOM   12345 N N   . LEU C 1 488 ? -83.415  -18.959 34.376  1.00 52.10  ? 548 LEU C N   1 
ATOM   12346 C CA  . LEU C 1 488 ? -83.384  -20.088 35.349  1.00 53.42  ? 548 LEU C CA  1 
ATOM   12347 C C   . LEU C 1 488 ? -82.564  -19.672 36.592  1.00 57.00  ? 548 LEU C C   1 
ATOM   12348 O O   . LEU C 1 488 ? -82.960  -20.020 37.746  1.00 55.56  ? 548 LEU C O   1 
ATOM   12349 C CB  . LEU C 1 488 ? -82.789  -21.321 34.656  1.00 52.51  ? 548 LEU C CB  1 
ATOM   12350 C CG  . LEU C 1 488 ? -83.666  -21.938 33.573  1.00 51.57  ? 548 LEU C CG  1 
ATOM   12351 C CD1 . LEU C 1 488 ? -83.008  -23.150 32.953  1.00 51.79  ? 548 LEU C CD1 1 
ATOM   12352 C CD2 . LEU C 1 488 ? -85.002  -22.335 34.143  1.00 52.83  ? 548 LEU C CD2 1 
ATOM   12353 N N   . VAL C 1 489 ? -81.467  -18.939 36.390  1.00 55.17  ? 549 VAL C N   1 
ATOM   12354 C CA  . VAL C 1 489 ? -80.593  -18.480 37.506  1.00 53.56  ? 549 VAL C CA  1 
ATOM   12355 C C   . VAL C 1 489 ? -81.334  -17.403 38.300  1.00 53.39  ? 549 VAL C C   1 
ATOM   12356 O O   . VAL C 1 489 ? -81.614  -17.694 39.446  1.00 58.67  ? 549 VAL C O   1 
ATOM   12357 C CB  . VAL C 1 489 ? -79.212  -18.003 37.011  1.00 57.70  ? 549 VAL C CB  1 
ATOM   12358 C CG1 . VAL C 1 489 ? -78.396  -17.324 38.117  1.00 53.98  ? 549 VAL C CG1 1 
ATOM   12359 C CG2 . VAL C 1 489 ? -78.430  -19.148 36.381  1.00 61.25  ? 549 VAL C CG2 1 
ATOM   12360 N N   . ILE C 1 490 ? -81.683  -16.244 37.723  1.00 50.61  ? 550 ILE C N   1 
ATOM   12361 C CA  . ILE C 1 490 ? -82.143  -15.053 38.510  1.00 52.03  ? 550 ILE C CA  1 
ATOM   12362 C C   . ILE C 1 490 ? -83.471  -15.339 39.235  1.00 48.12  ? 550 ILE C C   1 
ATOM   12363 O O   . ILE C 1 490 ? -83.868  -14.486 40.065  1.00 43.61  ? 550 ILE C O   1 
ATOM   12364 C CB  . ILE C 1 490 ? -82.262  -13.785 37.641  1.00 54.90  ? 550 ILE C CB  1 
ATOM   12365 C CG1 . ILE C 1 490 ? -83.340  -13.923 36.562  1.00 58.97  ? 550 ILE C CG1 1 
ATOM   12366 C CG2 . ILE C 1 490 ? -80.914  -13.394 37.059  1.00 54.94  ? 550 ILE C CG2 1 
ATOM   12367 C CD1 . ILE C 1 490 ? -83.440  -12.735 35.618  1.00 58.88  ? 550 ILE C CD1 1 
ATOM   12368 N N   . SER C 1 491 ? -84.139  -16.454 38.911  1.00 43.11  ? 551 SER C N   1 
ATOM   12369 C CA  . SER C 1 491 ? -85.420  -16.916 39.504  1.00 42.72  ? 551 SER C CA  1 
ATOM   12370 C C   . SER C 1 491 ? -85.154  -18.047 40.476  1.00 42.34  ? 551 SER C C   1 
ATOM   12371 O O   . SER C 1 491 ? -86.047  -18.379 41.283  1.00 54.99  ? 551 SER C O   1 
ATOM   12372 C CB  . SER C 1 491 ? -86.391  -17.391 38.447  1.00 50.38  ? 551 SER C CB  1 
ATOM   12373 O OG  . SER C 1 491 ? -86.172  -18.754 38.063  1.00 53.92  ? 551 SER C OG  1 
ATOM   12374 N N   . GLY C 1 492 ? -83.994  -18.670 40.369  1.00 44.19  ? 552 GLY C N   1 
ATOM   12375 C CA  . GLY C 1 492 ? -83.652  -19.841 41.190  1.00 47.84  ? 552 GLY C CA  1 
ATOM   12376 C C   . GLY C 1 492 ? -84.495  -21.043 40.826  1.00 44.64  ? 552 GLY C C   1 
ATOM   12377 O O   . GLY C 1 492 ? -84.768  -21.864 41.714  1.00 47.50  ? 552 GLY C O   1 
ATOM   12378 N N   . ALA C 1 493 ? -84.880  -21.170 39.569  1.00 42.38  ? 553 ALA C N   1 
ATOM   12379 C CA  . ALA C 1 493 ? -85.627  -22.347 39.086  1.00 51.15  ? 553 ALA C CA  1 
ATOM   12380 C C   . ALA C 1 493 ? -84.850  -23.631 39.429  1.00 51.37  ? 553 ALA C C   1 
ATOM   12381 O O   . ALA C 1 493 ? -83.625  -23.603 39.366  1.00 55.93  ? 553 ALA C O   1 
ATOM   12382 C CB  . ALA C 1 493 ? -85.849  -22.203 37.612  1.00 54.27  ? 553 ALA C CB  1 
ATOM   12383 N N   . VAL C 1 494 ? -85.554  -24.693 39.803  1.00 52.06  ? 554 VAL C N   1 
ATOM   12384 C CA  . VAL C 1 494 ? -84.983  -25.995 40.255  1.00 55.57  ? 554 VAL C CA  1 
ATOM   12385 C C   . VAL C 1 494 ? -85.297  -27.069 39.211  1.00 55.57  ? 554 VAL C C   1 
ATOM   12386 O O   . VAL C 1 494 ? -84.840  -28.227 39.363  1.00 61.68  ? 554 VAL C O   1 
ATOM   12387 C CB  . VAL C 1 494 ? -85.570  -26.421 41.620  1.00 64.57  ? 554 VAL C CB  1 
ATOM   12388 C CG1 . VAL C 1 494 ? -85.370  -25.353 42.682  1.00 61.87  ? 554 VAL C CG1 1 
ATOM   12389 C CG2 . VAL C 1 494 ? -87.046  -26.819 41.534  1.00 57.22  ? 554 VAL C CG2 1 
ATOM   12390 N N   . ARG C 1 495 ? -86.131  -26.736 38.233  1.00 61.67  ? 555 ARG C N   1 
ATOM   12391 C CA  . ARG C 1 495 ? -86.481  -27.663 37.123  1.00 69.23  ? 555 ARG C CA  1 
ATOM   12392 C C   . ARG C 1 495 ? -86.750  -26.852 35.855  1.00 73.46  ? 555 ARG C C   1 
ATOM   12393 O O   . ARG C 1 495 ? -87.122  -25.657 35.978  1.00 75.98  ? 555 ARG C O   1 
ATOM   12394 C CB  . ARG C 1 495 ? -87.690  -28.531 37.468  1.00 68.02  ? 555 ARG C CB  1 
ATOM   12395 C CG  . ARG C 1 495 ? -87.328  -29.964 37.813  1.00 75.74  ? 555 ARG C CG  1 
ATOM   12396 C CD  . ARG C 1 495 ? -88.330  -30.812 37.076  1.00 99.24  ? 555 ARG C CD  1 
ATOM   12397 N NE  . ARG C 1 495 ? -88.654  -32.043 37.760  1.00 134.45 ? 555 ARG C NE  1 
ATOM   12398 C CZ  . ARG C 1 495 ? -89.418  -33.019 37.247  1.00 149.54 ? 555 ARG C CZ  1 
ATOM   12399 N NH1 . ARG C 1 495 ? -89.973  -32.895 36.048  1.00 133.49 ? 555 ARG C NH1 1 
ATOM   12400 N NH2 . ARG C 1 495 ? -89.616  -34.138 37.929  1.00 144.57 ? 555 ARG C NH2 1 
ATOM   12401 N N   . VAL C 1 496 ? -86.544  -27.477 34.697  1.00 64.35  ? 556 VAL C N   1 
ATOM   12402 C CA  . VAL C 1 496 ? -86.880  -26.882 33.375  1.00 62.89  ? 556 VAL C CA  1 
ATOM   12403 C C   . VAL C 1 496 ? -88.214  -27.476 32.912  1.00 60.15  ? 556 VAL C C   1 
ATOM   12404 O O   . VAL C 1 496 ? -88.354  -28.730 32.957  1.00 47.98  ? 556 VAL C O   1 
ATOM   12405 C CB  . VAL C 1 496 ? -85.757  -27.142 32.372  1.00 66.93  ? 556 VAL C CB  1 
ATOM   12406 C CG1 . VAL C 1 496 ? -86.094  -26.523 31.037  1.00 71.19  ? 556 VAL C CG1 1 
ATOM   12407 C CG2 . VAL C 1 496 ? -84.428  -26.639 32.889  1.00 72.02  ? 556 VAL C CG2 1 
ATOM   12408 N N   . HIS C 1 497 ? -89.173  -26.612 32.556  1.00 58.32  ? 557 HIS C N   1 
ATOM   12409 C CA  . HIS C 1 497 ? -90.553  -27.012 32.161  1.00 66.68  ? 557 HIS C CA  1 
ATOM   12410 C C   . HIS C 1 497 ? -90.792  -26.626 30.700  1.00 63.57  ? 557 HIS C C   1 
ATOM   12411 O O   . HIS C 1 497 ? -90.497  -25.478 30.339  1.00 55.85  ? 557 HIS C O   1 
ATOM   12412 C CB  . HIS C 1 497 ? -91.618  -26.397 33.082  1.00 66.90  ? 557 HIS C CB  1 
ATOM   12413 C CG  . HIS C 1 497 ? -92.939  -27.107 33.067  1.00 67.04  ? 557 HIS C CG  1 
ATOM   12414 N ND1 . HIS C 1 497 ? -93.840  -27.025 32.004  1.00 64.55  ? 557 HIS C ND1 1 
ATOM   12415 C CD2 . HIS C 1 497 ? -93.527  -27.873 34.008  1.00 62.94  ? 557 HIS C CD2 1 
ATOM   12416 C CE1 . HIS C 1 497 ? -94.914  -27.730 32.292  1.00 75.85  ? 557 HIS C CE1 1 
ATOM   12417 N NE2 . HIS C 1 497 ? -94.742  -28.269 33.513  1.00 77.66  ? 557 HIS C NE2 1 
ATOM   12418 N N   . GLU C 1 498 ? -91.310  -27.571 29.912  1.00 62.21  ? 558 GLU C N   1 
ATOM   12419 C CA  . GLU C 1 498 ? -91.665  -27.360 28.491  1.00 57.93  ? 558 GLU C CA  1 
ATOM   12420 C C   . GLU C 1 498 ? -92.311  -25.969 28.374  1.00 52.90  ? 558 GLU C C   1 
ATOM   12421 O O   . GLU C 1 498 ? -92.006  -25.266 27.419  1.00 65.76  ? 558 GLU C O   1 
ATOM   12422 C CB  . GLU C 1 498 ? -92.520  -28.513 27.943  1.00 63.78  ? 558 GLU C CB  1 
ATOM   12423 C CG  . GLU C 1 498 ? -93.587  -29.043 28.881  1.00 79.51  ? 558 GLU C CG  1 
ATOM   12424 C CD  . GLU C 1 498 ? -93.167  -30.216 29.760  1.00 98.27  ? 558 GLU C CD  1 
ATOM   12425 O OE1 . GLU C 1 498 ? -92.319  -30.041 30.697  1.00 93.30  ? 558 GLU C OE1 1 
ATOM   12426 O OE2 . GLU C 1 498 ? -93.700  -31.310 29.519  1.00 107.52 ? 558 GLU C OE2 1 
ATOM   12427 N N   . ASP C 1 499 ? -93.106  -25.535 29.340  1.00 52.10  ? 559 ASP C N   1 
ATOM   12428 C CA  . ASP C 1 499 ? -93.792  -24.213 29.269  1.00 60.93  ? 559 ASP C CA  1 
ATOM   12429 C C   . ASP C 1 499 ? -92.788  -23.042 29.227  1.00 55.52  ? 559 ASP C C   1 
ATOM   12430 O O   . ASP C 1 499 ? -93.189  -21.967 28.778  1.00 52.09  ? 559 ASP C O   1 
ATOM   12431 C CB  . ASP C 1 499 ? -94.782  -24.026 30.425  1.00 62.60  ? 559 ASP C CB  1 
ATOM   12432 C CG  . ASP C 1 499 ? -96.075  -24.808 30.312  1.00 66.29  ? 559 ASP C CG  1 
ATOM   12433 O OD1 . ASP C 1 499 ? -96.048  -25.967 29.737  1.00 56.36  ? 559 ASP C OD1 1 
ATOM   12434 O OD2 . ASP C 1 499 ? -97.088  -24.251 30.829  1.00 62.49  ? 559 ASP C OD2 1 
ATOM   12435 N N   . MET C 1 500 ? -91.540  -23.224 29.672  1.00 58.06  ? 560 MET C N   1 
ATOM   12436 C CA  . MET C 1 500 ? -90.489  -22.159 29.704  1.00 57.79  ? 560 MET C CA  1 
ATOM   12437 C C   . MET C 1 500 ? -89.856  -22.001 28.308  1.00 54.82  ? 560 MET C C   1 
ATOM   12438 O O   . MET C 1 500 ? -89.543  -20.864 27.880  1.00 41.55  ? 560 MET C O   1 
ATOM   12439 C CB  . MET C 1 500 ? -89.398  -22.493 30.727  1.00 58.57  ? 560 MET C CB  1 
ATOM   12440 C CG  . MET C 1 500 ? -89.904  -22.791 32.119  1.00 52.79  ? 560 MET C CG  1 
ATOM   12441 S SD  . MET C 1 500 ? -88.545  -23.393 33.129  1.00 55.27  ? 560 MET C SD  1 
ATOM   12442 C CE  . MET C 1 500 ? -89.319  -23.521 34.736  1.00 55.42  ? 560 MET C CE  1 
ATOM   12443 N N   . LEU C 1 501 ? -89.670  -23.119 27.614  1.00 55.61  ? 561 LEU C N   1 
ATOM   12444 C CA  . LEU C 1 501 ? -89.264  -23.134 26.195  1.00 56.94  ? 561 LEU C CA  1 
ATOM   12445 C C   . LEU C 1 501 ? -90.246  -22.267 25.412  1.00 53.07  ? 561 LEU C C   1 
ATOM   12446 O O   . LEU C 1 501 ? -89.767  -21.410 24.652  1.00 63.33  ? 561 LEU C O   1 
ATOM   12447 C CB  . LEU C 1 501 ? -89.213  -24.581 25.716  1.00 58.49  ? 561 LEU C CB  1 
ATOM   12448 C CG  . LEU C 1 501 ? -88.302  -25.483 26.557  1.00 62.99  ? 561 LEU C CG  1 
ATOM   12449 C CD1 . LEU C 1 501 ? -88.368  -26.931 26.074  1.00 56.44  ? 561 LEU C CD1 1 
ATOM   12450 C CD2 . LEU C 1 501 ? -86.857  -24.958 26.566  1.00 64.12  ? 561 LEU C CD2 1 
ATOM   12451 N N   . LEU C 1 502 ? -91.554  -22.420 25.646  1.00 57.83  ? 562 LEU C N   1 
ATOM   12452 C CA  . LEU C 1 502 ? -92.615  -21.661 24.917  1.00 57.23  ? 562 LEU C CA  1 
ATOM   12453 C C   . LEU C 1 502 ? -92.525  -20.187 25.300  1.00 50.13  ? 562 LEU C C   1 
ATOM   12454 O O   . LEU C 1 502 ? -92.617  -19.350 24.389  1.00 53.36  ? 562 LEU C O   1 
ATOM   12455 C CB  . LEU C 1 502 ? -94.025  -22.185 25.238  1.00 61.02  ? 562 LEU C CB  1 
ATOM   12456 C CG  . LEU C 1 502 ? -94.320  -23.668 25.032  1.00 54.71  ? 562 LEU C CG  1 
ATOM   12457 C CD1 . LEU C 1 502 ? -95.803  -23.925 25.283  1.00 52.97  ? 562 LEU C CD1 1 
ATOM   12458 C CD2 . LEU C 1 502 ? -93.950  -24.100 23.635  1.00 51.58  ? 562 LEU C CD2 1 
ATOM   12459 N N   . ALA C 1 503 ? -92.356  -19.908 26.594  1.00 46.08  ? 563 ALA C N   1 
ATOM   12460 C CA  . ALA C 1 503 ? -92.293  -18.544 27.170  1.00 54.28  ? 563 ALA C CA  1 
ATOM   12461 C C   . ALA C 1 503 ? -91.162  -17.777 26.481  1.00 55.91  ? 563 ALA C C   1 
ATOM   12462 O O   . ALA C 1 503 ? -91.341  -16.582 26.154  1.00 45.77  ? 563 ALA C O   1 
ATOM   12463 C CB  . ALA C 1 503 ? -92.076  -18.621 28.667  1.00 56.54  ? 563 ALA C CB  1 
ATOM   12464 N N   . ALA C 1 504 ? -90.052  -18.479 26.256  1.00 57.38  ? 564 ALA C N   1 
ATOM   12465 C CA  . ALA C 1 504 ? -88.838  -17.975 25.583  1.00 63.62  ? 564 ALA C CA  1 
ATOM   12466 C C   . ALA C 1 504 ? -89.172  -17.692 24.121  1.00 57.36  ? 564 ALA C C   1 
ATOM   12467 O O   . ALA C 1 504 ? -88.944  -16.541 23.634  1.00 57.53  ? 564 ALA C O   1 
ATOM   12468 C CB  . ALA C 1 504 ? -87.738  -19.005 25.724  1.00 67.36  ? 564 ALA C CB  1 
ATOM   12469 N N   . SER C 1 505 ? -89.689  -18.711 23.441  1.00 56.13  ? 565 SER C N   1 
ATOM   12470 C CA  . SER C 1 505 ? -90.061  -18.637 22.011  1.00 54.73  ? 565 SER C CA  1 
ATOM   12471 C C   . SER C 1 505 ? -90.919  -17.379 21.801  1.00 54.79  ? 565 SER C C   1 
ATOM   12472 O O   . SER C 1 505 ? -90.574  -16.561 20.921  1.00 46.38  ? 565 SER C O   1 
ATOM   12473 C CB  . SER C 1 505 ? -90.769  -19.895 21.580  1.00 51.49  ? 565 SER C CB  1 
ATOM   12474 O OG  . SER C 1 505 ? -90.055  -21.048 21.986  1.00 53.39  ? 565 SER C OG  1 
ATOM   12475 N N   . LYS C 1 506 ? -91.973  -17.222 22.609  1.00 50.67  ? 566 LYS C N   1 
ATOM   12476 C CA  . LYS C 1 506 ? -92.868  -16.044 22.570  1.00 52.58  ? 566 LYS C CA  1 
ATOM   12477 C C   . LYS C 1 506 ? -92.020  -14.776 22.714  1.00 53.40  ? 566 LYS C C   1 
ATOM   12478 O O   . LYS C 1 506 ? -92.208  -13.851 21.907  1.00 48.25  ? 566 LYS C O   1 
ATOM   12479 C CB  . LYS C 1 506 ? -93.975  -16.132 23.630  1.00 69.37  ? 566 LYS C CB  1 
ATOM   12480 C CG  . LYS C 1 506 ? -95.065  -17.175 23.362  1.00 101.10 ? 566 LYS C CG  1 
ATOM   12481 C CD  . LYS C 1 506 ? -96.486  -16.820 23.868  1.00 113.53 ? 566 LYS C CD  1 
ATOM   12482 C CE  . LYS C 1 506 ? -97.336  -18.039 24.194  1.00 106.03 ? 566 LYS C CE  1 
ATOM   12483 N NZ  . LYS C 1 506 ? -97.722  -18.789 22.971  1.00 105.35 ? 566 LYS C NZ  1 
ATOM   12484 N N   . ALA C 1 507 ? -91.108  -14.730 23.692  1.00 56.32  ? 567 ALA C N   1 
ATOM   12485 C CA  . ALA C 1 507 ? -90.378  -13.505 24.092  1.00 50.99  ? 567 ALA C CA  1 
ATOM   12486 C C   . ALA C 1 507 ? -89.521  -13.030 22.922  1.00 56.12  ? 567 ALA C C   1 
ATOM   12487 O O   . ALA C 1 507 ? -89.479  -11.795 22.654  1.00 62.42  ? 567 ALA C O   1 
ATOM   12488 C CB  . ALA C 1 507 ? -89.548  -13.785 25.310  1.00 47.97  ? 567 ALA C CB  1 
ATOM   12489 N N   . LEU C 1 508 ? -88.870  -13.981 22.253  1.00 56.88  ? 568 LEU C N   1 
ATOM   12490 C CA  . LEU C 1 508 ? -87.957  -13.701 21.117  1.00 59.43  ? 568 LEU C CA  1 
ATOM   12491 C C   . LEU C 1 508 ? -88.792  -13.165 19.958  1.00 59.04  ? 568 LEU C C   1 
ATOM   12492 O O   . LEU C 1 508 ? -88.452  -12.117 19.388  1.00 49.11  ? 568 LEU C O   1 
ATOM   12493 C CB  . LEU C 1 508 ? -87.220  -14.993 20.729  1.00 53.02  ? 568 LEU C CB  1 
ATOM   12494 C CG  . LEU C 1 508 ? -86.344  -14.886 19.481  1.00 53.20  ? 568 LEU C CG  1 
ATOM   12495 C CD1 . LEU C 1 508 ? -85.373  -13.704 19.611  1.00 57.78  ? 568 LEU C CD1 1 
ATOM   12496 C CD2 . LEU C 1 508 ? -85.611  -16.203 19.207  1.00 52.72  ? 568 LEU C CD2 1 
ATOM   12497 N N   . ALA C 1 509 ? -89.834  -13.925 19.618  1.00 65.54  ? 569 ALA C N   1 
ATOM   12498 C CA  . ALA C 1 509 ? -90.756  -13.646 18.503  1.00 59.26  ? 569 ALA C CA  1 
ATOM   12499 C C   . ALA C 1 509 ? -91.319  -12.239 18.678  1.00 55.12  ? 569 ALA C C   1 
ATOM   12500 O O   . ALA C 1 509 ? -91.445  -11.539 17.652  1.00 50.83  ? 569 ALA C O   1 
ATOM   12501 C CB  . ALA C 1 509 ? -91.822  -14.701 18.470  1.00 57.57  ? 569 ALA C CB  1 
ATOM   12502 N N   . ASP C 1 510 ? -91.580  -11.824 19.926  1.00 54.02  ? 570 ASP C N   1 
ATOM   12503 C CA  . ASP C 1 510 ? -92.256  -10.533 20.236  1.00 53.77  ? 570 ASP C CA  1 
ATOM   12504 C C   . ASP C 1 510 ? -91.228  -9.398  20.194  1.00 50.86  ? 570 ASP C C   1 
ATOM   12505 O O   . ASP C 1 510 ? -91.646  -8.241  20.311  1.00 57.04  ? 570 ASP C O   1 
ATOM   12506 C CB  . ASP C 1 510 ? -93.050  -10.601 21.545  1.00 55.37  ? 570 ASP C CB  1 
ATOM   12507 C CG  . ASP C 1 510 ? -94.442  -11.239 21.450  1.00 68.16  ? 570 ASP C CG  1 
ATOM   12508 O OD1 . ASP C 1 510 ? -94.750  -11.918 20.429  1.00 75.53  ? 570 ASP C OD1 1 
ATOM   12509 O OD2 . ASP C 1 510 ? -95.224  -11.073 22.403  1.00 68.25  ? 570 ASP C OD2 1 
ATOM   12510 N N   . GLN C 1 511 ? -89.953  -9.711  19.968  1.00 49.60  ? 571 GLN C N   1 
ATOM   12511 C CA  . GLN C 1 511 ? -88.880  -8.717  19.726  1.00 51.58  ? 571 GLN C CA  1 
ATOM   12512 C C   . GLN C 1 511 ? -88.691  -8.477  18.221  1.00 54.11  ? 571 GLN C C   1 
ATOM   12513 O O   . GLN C 1 511 ? -88.012  -7.479  17.871  1.00 57.68  ? 571 GLN C O   1 
ATOM   12514 C CB  . GLN C 1 511 ? -87.582  -9.216  20.357  1.00 51.80  ? 571 GLN C CB  1 
ATOM   12515 C CG  . GLN C 1 511 ? -87.611  -9.163  21.866  1.00 53.04  ? 571 GLN C CG  1 
ATOM   12516 C CD  . GLN C 1 511 ? -87.812  -7.747  22.340  1.00 57.67  ? 571 GLN C CD  1 
ATOM   12517 O OE1 . GLN C 1 511 ? -87.183  -6.807  21.837  1.00 56.31  ? 571 GLN C OE1 1 
ATOM   12518 N NE2 . GLN C 1 511 ? -88.683  -7.603  23.333  1.00 64.79  ? 571 GLN C NE2 1 
ATOM   12519 N N   . ALA C 1 512 ? -89.248  -9.351  17.372  1.00 55.12  ? 572 ALA C N   1 
ATOM   12520 C CA  . ALA C 1 512 ? -89.191  -9.264  15.889  1.00 62.85  ? 572 ALA C CA  1 
ATOM   12521 C C   . ALA C 1 512 ? -90.144  -8.173  15.406  1.00 58.49  ? 572 ALA C C   1 
ATOM   12522 O O   . ALA C 1 512 ? -91.347  -8.369  15.488  1.00 67.00  ? 572 ALA C O   1 
ATOM   12523 C CB  . ALA C 1 512 ? -89.512  -10.600 15.258  1.00 61.21  ? 572 ALA C CB  1 
ATOM   12524 N N   . THR C 1 513 ? -89.604  -7.051  14.959  1.00 59.49  ? 573 THR C N   1 
ATOM   12525 C CA  . THR C 1 513 ? -90.377  -5.878  14.497  1.00 57.91  ? 573 THR C CA  1 
ATOM   12526 C C   . THR C 1 513 ? -90.287  -5.822  12.971  1.00 66.93  ? 573 THR C C   1 
ATOM   12527 O O   . THR C 1 513 ? -89.682  -6.729  12.374  1.00 59.19  ? 573 THR C O   1 
ATOM   12528 C CB  . THR C 1 513 ? -89.847  -4.593  15.138  1.00 54.40  ? 573 THR C CB  1 
ATOM   12529 O OG1 . THR C 1 513 ? -88.786  -4.107  14.305  1.00 50.66  ? 573 THR C OG1 1 
ATOM   12530 C CG2 . THR C 1 513 ? -89.405  -4.798  16.575  1.00 52.78  ? 573 THR C CG2 1 
ATOM   12531 N N   . GLN C 1 514 ? -90.868  -4.777  12.387  1.00 79.15  ? 574 GLN C N   1 
ATOM   12532 C CA  . GLN C 1 514 ? -90.857  -4.477  10.935  1.00 92.07  ? 574 GLN C CA  1 
ATOM   12533 C C   . GLN C 1 514 ? -89.441  -4.121  10.469  1.00 96.25  ? 574 GLN C C   1 
ATOM   12534 O O   . GLN C 1 514 ? -89.143  -4.373  9.271   1.00 102.86 ? 574 GLN C O   1 
ATOM   12535 C CB  . GLN C 1 514 ? -91.726  -3.245  10.658  1.00 94.60  ? 574 GLN C CB  1 
ATOM   12536 C CG  . GLN C 1 514 ? -92.931  -3.498  9.765   1.00 99.06  ? 574 GLN C CG  1 
ATOM   12537 C CD  . GLN C 1 514 ? -93.413  -2.220  9.115   1.00 99.28  ? 574 GLN C CD  1 
ATOM   12538 O OE1 . GLN C 1 514 ? -93.049  -1.107  9.512   1.00 91.54  ? 574 GLN C OE1 1 
ATOM   12539 N NE2 . GLN C 1 514 ? -94.241  -2.372  8.093   1.00 92.12  ? 574 GLN C NE2 1 
ATOM   12540 N N   . ASP C 1 515 ? -88.633  -3.517  11.354  1.00 93.21  ? 575 ASP C N   1 
ATOM   12541 C CA  . ASP C 1 515 ? -87.264  -3.041  11.008  1.00 85.07  ? 575 ASP C CA  1 
ATOM   12542 C C   . ASP C 1 515 ? -86.508  -4.230  10.403  1.00 72.05  ? 575 ASP C C   1 
ATOM   12543 O O   . ASP C 1 515 ? -85.865  -4.054  9.345   1.00 56.48  ? 575 ASP C O   1 
ATOM   12544 C CB  . ASP C 1 515 ? -86.543  -2.435  12.218  1.00 90.70  ? 575 ASP C CB  1 
ATOM   12545 C CG  . ASP C 1 515 ? -87.338  -1.362  12.938  1.00 92.39  ? 575 ASP C CG  1 
ATOM   12546 O OD1 . ASP C 1 515 ? -88.531  -1.223  12.635  1.00 121.42 ? 575 ASP C OD1 1 
ATOM   12547 O OD2 . ASP C 1 515 ? -86.779  -0.720  13.823  1.00 83.02  ? 575 ASP C OD2 1 
ATOM   12548 N N   . ASN C 1 516 ? -86.645  -5.410  11.023  1.00 62.40  ? 576 ASN C N   1 
ATOM   12549 C CA  . ASN C 1 516 ? -85.922  -6.623  10.592  1.00 59.64  ? 576 ASN C CA  1 
ATOM   12550 C C   . ASN C 1 516 ? -86.765  -7.385  9.580   1.00 56.96  ? 576 ASN C C   1 
ATOM   12551 O O   . ASN C 1 516 ? -86.159  -7.979  8.680   1.00 60.17  ? 576 ASN C O   1 
ATOM   12552 C CB  . ASN C 1 516 ? -85.461  -7.477  11.768  1.00 67.71  ? 576 ASN C CB  1 
ATOM   12553 C CG  . ASN C 1 516 ? -86.546  -7.833  12.751  1.00 67.45  ? 576 ASN C CG  1 
ATOM   12554 O OD1 . ASN C 1 516 ? -86.872  -7.027  13.614  1.00 57.86  ? 576 ASN C OD1 1 
ATOM   12555 N ND2 . ASN C 1 516 ? -87.044  -9.056  12.653  1.00 66.92  ? 576 ASN C ND2 1 
ATOM   12556 N N   . PHE C 1 517 ? -88.101  -7.332  9.671   1.00 63.82  ? 577 PHE C N   1 
ATOM   12557 C CA  . PHE C 1 517 ? -89.008  -7.980  8.680   1.00 62.39  ? 577 PHE C CA  1 
ATOM   12558 C C   . PHE C 1 517 ? -88.836  -7.344  7.289   1.00 62.86  ? 577 PHE C C   1 
ATOM   12559 O O   . PHE C 1 517 ? -88.806  -8.114  6.307   1.00 52.31  ? 577 PHE C O   1 
ATOM   12560 C CB  . PHE C 1 517 ? -90.473  -7.883  9.103   1.00 63.49  ? 577 PHE C CB  1 
ATOM   12561 C CG  . PHE C 1 517 ? -90.879  -8.733  10.274  1.00 65.35  ? 577 PHE C CG  1 
ATOM   12562 C CD1 . PHE C 1 517 ? -90.144  -9.849  10.647  1.00 70.91  ? 577 PHE C CD1 1 
ATOM   12563 C CD2 . PHE C 1 517 ? -92.025  -8.428  10.987  1.00 64.09  ? 577 PHE C CD2 1 
ATOM   12564 C CE1 . PHE C 1 517 ? -90.517  -10.616 11.739  1.00 74.93  ? 577 PHE C CE1 1 
ATOM   12565 C CE2 . PHE C 1 517 ? -92.398  -9.202  12.074  1.00 66.00  ? 577 PHE C CE2 1 
ATOM   12566 C CZ  . PHE C 1 517 ? -91.644  -10.293 12.447  1.00 67.41  ? 577 PHE C CZ  1 
ATOM   12567 N N   . GLU C 1 518 ? -88.792  -6.003  7.216   1.00 70.53  ? 578 GLU C N   1 
ATOM   12568 C CA  . GLU C 1 518 ? -88.473  -5.224  5.990   1.00 66.62  ? 578 GLU C CA  1 
ATOM   12569 C C   . GLU C 1 518 ? -87.374  -5.942  5.203   1.00 62.79  ? 578 GLU C C   1 
ATOM   12570 O O   . GLU C 1 518 ? -87.630  -6.251  4.052   1.00 76.72  ? 578 GLU C O   1 
ATOM   12571 C CB  . GLU C 1 518 ? -88.040  -3.798  6.330   1.00 75.30  ? 578 GLU C CB  1 
ATOM   12572 C CG  . GLU C 1 518 ? -89.195  -2.803  6.382   1.00 80.15  ? 578 GLU C CG  1 
ATOM   12573 C CD  . GLU C 1 518 ? -88.787  -1.373  6.703   1.00 86.05  ? 578 GLU C CD  1 
ATOM   12574 O OE1 . GLU C 1 518 ? -87.567  -1.094  6.809   1.00 91.02  ? 578 GLU C OE1 1 
ATOM   12575 O OE2 . GLU C 1 518 ? -89.692  -0.536  6.827   1.00 84.74  ? 578 GLU C OE2 1 
ATOM   12576 N N   . LYS C 1 519 ? -86.226  -6.237  5.820   1.00 63.17  ? 579 LYS C N   1 
ATOM   12577 C CA  . LYS C 1 519 ? -85.039  -6.845  5.158   1.00 64.00  ? 579 LYS C CA  1 
ATOM   12578 C C   . LYS C 1 519 ? -85.179  -8.368  4.996   1.00 68.43  ? 579 LYS C C   1 
ATOM   12579 O O   . LYS C 1 519 ? -84.199  -8.977  4.564   1.00 78.39  ? 579 LYS C O   1 
ATOM   12580 C CB  . LYS C 1 519 ? -83.772  -6.595  5.982   1.00 71.50  ? 579 LYS C CB  1 
ATOM   12581 C CG  . LYS C 1 519 ? -83.481  -5.134  6.287   1.00 74.98  ? 579 LYS C CG  1 
ATOM   12582 C CD  . LYS C 1 519 ? -82.622  -4.947  7.510   1.00 82.42  ? 579 LYS C CD  1 
ATOM   12583 C CE  . LYS C 1 519 ? -82.591  -3.509  7.963   1.00 84.51  ? 579 LYS C CE  1 
ATOM   12584 N NZ  . LYS C 1 519 ? -81.569  -2.777  7.197   1.00 87.19  ? 579 LYS C NZ  1 
ATOM   12585 N N   . GLY C 1 520 ? -86.305  -8.984  5.364   1.00 70.69  ? 580 GLY C N   1 
ATOM   12586 C CA  . GLY C 1 520 ? -86.554  -10.425 5.151   1.00 66.08  ? 580 GLY C CA  1 
ATOM   12587 C C   . GLY C 1 520 ? -86.014  -11.293 6.288   1.00 72.75  ? 580 GLY C C   1 
ATOM   12588 O O   . GLY C 1 520 ? -85.910  -12.519 6.075   1.00 73.54  ? 580 GLY C O   1 
ATOM   12589 N N   . SER C 1 521 ? -85.732  -10.702 7.464   1.00 73.49  ? 581 SER C N   1 
ATOM   12590 C CA  . SER C 1 521 ? -85.154  -11.370 8.660   1.00 69.99  ? 581 SER C CA  1 
ATOM   12591 C C   . SER C 1 521 ? -86.237  -11.610 9.720   1.00 59.76  ? 581 SER C C   1 
ATOM   12592 O O   . SER C 1 521 ? -86.802  -10.613 10.228  1.00 46.42  ? 581 SER C O   1 
ATOM   12593 C CB  . SER C 1 521 ? -84.034  -10.550 9.241   1.00 74.05  ? 581 SER C CB  1 
ATOM   12594 O OG  . SER C 1 521 ? -83.039  -11.375 9.814   1.00 83.67  ? 581 SER C OG  1 
ATOM   12595 N N   . ILE C 1 522 ? -86.403  -12.875 10.121  1.00 49.20  ? 582 ILE C N   1 
ATOM   12596 C CA  . ILE C 1 522 ? -87.391  -13.282 11.152  1.00 50.16  ? 582 ILE C CA  1 
ATOM   12597 C C   . ILE C 1 522 ? -86.930  -12.796 12.534  1.00 56.32  ? 582 ILE C C   1 
ATOM   12598 O O   . ILE C 1 522 ? -87.765  -12.712 13.442  1.00 71.23  ? 582 ILE C O   1 
ATOM   12599 C CB  . ILE C 1 522 ? -87.620  -14.800 11.104  1.00 48.69  ? 582 ILE C CB  1 
ATOM   12600 C CG1 . ILE C 1 522 ? -86.412  -15.610 11.541  1.00 54.57  ? 582 ILE C CG1 1 
ATOM   12601 C CG2 . ILE C 1 522 ? -88.036  -15.227 9.721   1.00 56.26  ? 582 ILE C CG2 1 
ATOM   12602 C CD1 . ILE C 1 522 ? -86.602  -17.094 11.370  1.00 60.77  ? 582 ILE C CD1 1 
ATOM   12603 N N   . PHE C 1 523 ? -85.648  -12.508 12.720  1.00 51.59  ? 583 PHE C N   1 
ATOM   12604 C CA  . PHE C 1 523 ? -85.091  -12.102 14.024  1.00 50.84  ? 583 PHE C CA  1 
ATOM   12605 C C   . PHE C 1 523 ? -84.434  -10.741 13.915  1.00 51.17  ? 583 PHE C C   1 
ATOM   12606 O O   . PHE C 1 523 ? -83.947  -10.353 12.866  1.00 56.39  ? 583 PHE C O   1 
ATOM   12607 C CB  . PHE C 1 523 ? -84.025  -13.085 14.466  1.00 52.84  ? 583 PHE C CB  1 
ATOM   12608 C CG  . PHE C 1 523 ? -84.547  -14.474 14.643  1.00 54.58  ? 583 PHE C CG  1 
ATOM   12609 C CD1 . PHE C 1 523 ? -85.583  -14.722 15.514  1.00 62.73  ? 583 PHE C CD1 1 
ATOM   12610 C CD2 . PHE C 1 523 ? -83.970  -15.534 13.968  1.00 65.94  ? 583 PHE C CD2 1 
ATOM   12611 C CE1 . PHE C 1 523 ? -86.016  -16.017 15.734  1.00 74.12  ? 583 PHE C CE1 1 
ATOM   12612 C CE2 . PHE C 1 523 ? -84.431  -16.830 14.162  1.00 70.57  ? 583 PHE C CE2 1 
ATOM   12613 C CZ  . PHE C 1 523 ? -85.441  -17.068 15.061  1.00 72.78  ? 583 PHE C CZ  1 
ATOM   12614 N N   . PRO C 1 524 ? -84.343  -9.989  15.018  1.00 52.45  ? 584 PRO C N   1 
ATOM   12615 C CA  . PRO C 1 524 ? -83.636  -8.718  14.991  1.00 57.34  ? 584 PRO C CA  1 
ATOM   12616 C C   . PRO C 1 524 ? -82.140  -9.010  14.944  1.00 56.95  ? 584 PRO C C   1 
ATOM   12617 O O   . PRO C 1 524 ? -81.699  -10.120 15.267  1.00 48.08  ? 584 PRO C O   1 
ATOM   12618 C CB  . PRO C 1 524 ? -84.094  -7.996  16.268  1.00 58.42  ? 584 PRO C CB  1 
ATOM   12619 C CG  . PRO C 1 524 ? -84.597  -9.098  17.178  1.00 57.19  ? 584 PRO C CG  1 
ATOM   12620 C CD  . PRO C 1 524 ? -84.904  -10.314 16.329  1.00 55.76  ? 584 PRO C CD  1 
ATOM   12621 N N   . PRO C 1 525 ? -81.314  -8.008  14.589  1.00 57.58  ? 585 PRO C N   1 
ATOM   12622 C CA  . PRO C 1 525 ? -79.872  -8.231  14.497  1.00 55.65  ? 585 PRO C CA  1 
ATOM   12623 C C   . PRO C 1 525 ? -79.305  -8.572  15.891  1.00 48.69  ? 585 PRO C C   1 
ATOM   12624 O O   . PRO C 1 525 ? -79.936  -8.260  16.862  1.00 46.68  ? 585 PRO C O   1 
ATOM   12625 C CB  . PRO C 1 525 ? -79.367  -6.879  13.917  1.00 55.68  ? 585 PRO C CB  1 
ATOM   12626 C CG  . PRO C 1 525 ? -80.407  -5.849  14.324  1.00 48.51  ? 585 PRO C CG  1 
ATOM   12627 C CD  . PRO C 1 525 ? -81.712  -6.606  14.354  1.00 51.49  ? 585 PRO C CD  1 
ATOM   12628 N N   . PHE C 1 526 ? -78.126  -9.192  15.969  1.00 50.89  ? 586 PHE C N   1 
ATOM   12629 C CA  . PHE C 1 526 ? -77.462  -9.571  17.243  1.00 48.77  ? 586 PHE C CA  1 
ATOM   12630 C C   . PHE C 1 526 ? -77.026  -8.328  18.019  1.00 45.94  ? 586 PHE C C   1 
ATOM   12631 O O   . PHE C 1 526 ? -76.789  -8.455  19.229  1.00 45.28  ? 586 PHE C O   1 
ATOM   12632 C CB  . PHE C 1 526 ? -76.258  -10.462 16.988  1.00 48.88  ? 586 PHE C CB  1 
ATOM   12633 C CG  . PHE C 1 526 ? -76.567  -11.923 16.996  1.00 45.46  ? 586 PHE C CG  1 
ATOM   12634 C CD1 . PHE C 1 526 ? -77.034  -12.515 18.133  1.00 49.79  ? 586 PHE C CD1 1 
ATOM   12635 C CD2 . PHE C 1 526 ? -76.343  -12.707 15.888  1.00 56.21  ? 586 PHE C CD2 1 
ATOM   12636 C CE1 . PHE C 1 526 ? -77.282  -13.881 18.175  1.00 59.19  ? 586 PHE C CE1 1 
ATOM   12637 C CE2 . PHE C 1 526 ? -76.581  -14.075 15.919  1.00 61.17  ? 586 PHE C CE2 1 
ATOM   12638 C CZ  . PHE C 1 526 ? -77.054  -14.660 17.070  1.00 61.37  ? 586 PHE C CZ  1 
ATOM   12639 N N   . THR C 1 527 ? -76.928  -7.180  17.359  1.00 45.79  ? 587 THR C N   1 
ATOM   12640 C CA  . THR C 1 527 ? -76.717  -5.849  17.993  1.00 51.62  ? 587 THR C CA  1 
ATOM   12641 C C   . THR C 1 527 ? -77.780  -5.522  19.057  1.00 55.47  ? 587 THR C C   1 
ATOM   12642 O O   . THR C 1 527 ? -77.656  -4.446  19.656  1.00 52.82  ? 587 THR C O   1 
ATOM   12643 C CB  . THR C 1 527 ? -76.745  -4.727  16.951  1.00 50.92  ? 587 THR C CB  1 
ATOM   12644 O OG1 . THR C 1 527 ? -78.052  -4.708  16.358  1.00 56.52  ? 587 THR C OG1 1 
ATOM   12645 C CG2 . THR C 1 527 ? -75.694  -4.906  15.878  1.00 53.02  ? 587 THR C CG2 1 
ATOM   12646 N N   . SER C 1 528 ? -78.808  -6.368  19.259  1.00 64.60  ? 588 SER C N   1 
ATOM   12647 C CA  . SER C 1 528 ? -79.920  -6.151  20.237  1.00 63.90  ? 588 SER C CA  1 
ATOM   12648 C C   . SER C 1 528 ? -79.986  -7.287  21.271  1.00 63.81  ? 588 SER C C   1 
ATOM   12649 O O   . SER C 1 528 ? -80.924  -7.254  22.096  1.00 55.70  ? 588 SER C O   1 
ATOM   12650 C CB  . SER C 1 528 ? -81.252  -6.012  19.534  1.00 55.41  ? 588 SER C CB  1 
ATOM   12651 O OG  . SER C 1 528 ? -81.155  -5.119  18.436  1.00 59.99  ? 588 SER C OG  1 
ATOM   12652 N N   . ILE C 1 529 ? -79.052  -8.253  21.217  1.00 59.94  ? 589 ILE C N   1 
ATOM   12653 C CA  . ILE C 1 529 ? -79.130  -9.545  21.961  1.00 57.21  ? 589 ILE C CA  1 
ATOM   12654 C C   . ILE C 1 529 ? -79.137  -9.270  23.479  1.00 59.47  ? 589 ILE C C   1 
ATOM   12655 O O   . ILE C 1 529 ? -79.581  -10.139 24.258  1.00 64.27  ? 589 ILE C O   1 
ATOM   12656 C CB  . ILE C 1 529 ? -77.971  -10.473 21.535  1.00 57.60  ? 589 ILE C CB  1 
ATOM   12657 C CG1 . ILE C 1 529 ? -78.146  -11.918 22.033  1.00 56.73  ? 589 ILE C CG1 1 
ATOM   12658 C CG2 . ILE C 1 529 ? -76.620  -9.904  21.988  1.00 53.91  ? 589 ILE C CG2 1 
ATOM   12659 C CD1 . ILE C 1 529 ? -79.354  -12.655 21.512  1.00 51.23  ? 589 ILE C CD1 1 
ATOM   12660 N N   . ARG C 1 530 ? -78.662  -8.114  23.916  1.00 60.05  ? 590 ARG C N   1 
ATOM   12661 C CA  . ARG C 1 530 ? -78.727  -7.719  25.342  1.00 72.12  ? 590 ARG C CA  1 
ATOM   12662 C C   . ARG C 1 530 ? -80.205  -7.475  25.717  1.00 69.03  ? 590 ARG C C   1 
ATOM   12663 O O   . ARG C 1 530 ? -80.706  -8.065  26.700  1.00 51.84  ? 590 ARG C O   1 
ATOM   12664 C CB  . ARG C 1 530 ? -77.838  -6.478  25.508  1.00 91.61  ? 590 ARG C CB  1 
ATOM   12665 C CG  . ARG C 1 530 ? -76.939  -6.497  26.735  1.00 86.34  ? 590 ARG C CG  1 
ATOM   12666 C CD  . ARG C 1 530 ? -75.964  -7.653  26.745  1.00 73.18  ? 590 ARG C CD  1 
ATOM   12667 N NE  . ARG C 1 530 ? -75.300  -7.598  28.038  1.00 73.58  ? 590 ARG C NE  1 
ATOM   12668 C CZ  . ARG C 1 530 ? -74.183  -8.217  28.351  1.00 66.41  ? 590 ARG C CZ  1 
ATOM   12669 N NH1 . ARG C 1 530 ? -73.544  -8.948  27.456  1.00 67.29  ? 590 ARG C NH1 1 
ATOM   12670 N NH2 . ARG C 1 530 ? -73.696  -8.066  29.569  1.00 59.39  ? 590 ARG C NH2 1 
ATOM   12671 N N   . LYS C 1 531 ? -80.899  -6.640  24.938  1.00 70.61  ? 591 LYS C N   1 
ATOM   12672 C CA  . LYS C 1 531 ? -82.354  -6.414  25.107  1.00 67.50  ? 591 LYS C CA  1 
ATOM   12673 C C   . LYS C 1 531 ? -83.085  -7.775  24.999  1.00 59.85  ? 591 LYS C C   1 
ATOM   12674 O O   . LYS C 1 531 ? -83.870  -8.080  25.887  1.00 54.63  ? 591 LYS C O   1 
ATOM   12675 C CB  . LYS C 1 531 ? -82.825  -5.351  24.106  1.00 66.40  ? 591 LYS C CB  1 
ATOM   12676 C CG  . LYS C 1 531 ? -84.225  -4.796  24.322  1.00 82.72  ? 591 LYS C CG  1 
ATOM   12677 C CD  . LYS C 1 531 ? -84.476  -3.512  23.575  1.00 100.58 ? 591 LYS C CD  1 
ATOM   12678 C CE  . LYS C 1 531 ? -84.974  -3.718  22.159  1.00 101.11 ? 591 LYS C CE  1 
ATOM   12679 N NZ  . LYS C 1 531 ? -86.019  -2.715  21.880  1.00 109.63 ? 591 LYS C NZ  1 
ATOM   12680 N N   . ILE C 1 532 ? -82.840  -8.590  23.969  1.00 47.61  ? 592 ILE C N   1 
ATOM   12681 C CA  . ILE C 1 532 ? -83.554  -9.889  23.752  1.00 48.12  ? 592 ILE C CA  1 
ATOM   12682 C C   . ILE C 1 532 ? -83.400  -10.817 24.951  1.00 47.34  ? 592 ILE C C   1 
ATOM   12683 O O   . ILE C 1 532 ? -84.376  -11.484 25.290  1.00 45.32  ? 592 ILE C O   1 
ATOM   12684 C CB  . ILE C 1 532 ? -83.057  -10.605 22.489  1.00 50.13  ? 592 ILE C CB  1 
ATOM   12685 C CG1 . ILE C 1 532 ? -83.553  -9.863  21.232  1.00 53.91  ? 592 ILE C CG1 1 
ATOM   12686 C CG2 . ILE C 1 532 ? -83.458  -12.081 22.503  1.00 44.44  ? 592 ILE C CG2 1 
ATOM   12687 C CD1 . ILE C 1 532 ? -82.605  -9.923  20.038  1.00 54.74  ? 592 ILE C CD1 1 
ATOM   12688 N N   . SER C 1 533 ? -82.196  -10.924 25.506  1.00 49.90  ? 593 SER C N   1 
ATOM   12689 C CA  . SER C 1 533 ? -81.860  -11.878 26.594  1.00 50.31  ? 593 SER C CA  1 
ATOM   12690 C C   . SER C 1 533 ? -82.630  -11.488 27.858  1.00 49.50  ? 593 SER C C   1 
ATOM   12691 O O   . SER C 1 533 ? -83.167  -12.415 28.520  1.00 52.05  ? 593 SER C O   1 
ATOM   12692 C CB  . SER C 1 533 ? -80.361  -12.008 26.788  1.00 44.08  ? 593 SER C CB  1 
ATOM   12693 O OG  . SER C 1 533 ? -79.827  -12.959 25.873  1.00 42.28  ? 593 SER C OG  1 
ATOM   12694 N N   . ALA C 1 534 ? -82.718  -10.182 28.152  1.00 50.10  ? 594 ALA C N   1 
ATOM   12695 C CA  . ALA C 1 534 ? -83.463  -9.619  29.312  1.00 51.53  ? 594 ALA C CA  1 
ATOM   12696 C C   . ALA C 1 534 ? -84.944  -9.997  29.201  1.00 47.85  ? 594 ALA C C   1 
ATOM   12697 O O   . ALA C 1 534 ? -85.494  -10.515 30.180  1.00 48.73  ? 594 ALA C O   1 
ATOM   12698 C CB  . ALA C 1 534 ? -83.294  -8.112  29.411  1.00 53.40  ? 594 ALA C CB  1 
ATOM   12699 N N   . HIS C 1 535 ? -85.562  -9.749  28.045  1.00 45.14  ? 595 HIS C N   1 
ATOM   12700 C CA  . HIS C 1 535 ? -86.978  -10.090 27.775  1.00 44.82  ? 595 HIS C CA  1 
ATOM   12701 C C   . HIS C 1 535 ? -87.160  -11.613 27.829  1.00 47.34  ? 595 HIS C C   1 
ATOM   12702 O O   . HIS C 1 535 ? -88.151  -12.032 28.398  1.00 60.86  ? 595 HIS C O   1 
ATOM   12703 C CB  . HIS C 1 535 ? -87.468  -9.468  26.474  1.00 42.97  ? 595 HIS C CB  1 
ATOM   12704 C CG  . HIS C 1 535 ? -87.745  -8.013  26.600  1.00 50.22  ? 595 HIS C CG  1 
ATOM   12705 N ND1 . HIS C 1 535 ? -86.744  -7.058  26.550  1.00 55.91  ? 595 HIS C ND1 1 
ATOM   12706 C CD2 . HIS C 1 535 ? -88.898  -7.334  26.765  1.00 58.14  ? 595 HIS C CD2 1 
ATOM   12707 C CE1 . HIS C 1 535 ? -87.257  -5.853  26.688  1.00 60.08  ? 595 HIS C CE1 1 
ATOM   12708 N NE2 . HIS C 1 535 ? -88.586  -5.993  26.805  1.00 63.41  ? 595 HIS C NE2 1 
ATOM   12709 N N   . ILE C 1 536 ? -86.244  -12.421 27.307  1.00 46.91  ? 596 ILE C N   1 
ATOM   12710 C CA  . ILE C 1 536 ? -86.375  -13.904 27.392  1.00 49.46  ? 596 ILE C CA  1 
ATOM   12711 C C   . ILE C 1 536 ? -86.226  -14.305 28.866  1.00 51.41  ? 596 ILE C C   1 
ATOM   12712 O O   . ILE C 1 536 ? -86.986  -15.169 29.342  1.00 55.11  ? 596 ILE C O   1 
ATOM   12713 C CB  . ILE C 1 536 ? -85.357  -14.630 26.495  1.00 51.09  ? 596 ILE C CB  1 
ATOM   12714 C CG1 . ILE C 1 536 ? -85.623  -14.338 25.018  1.00 53.99  ? 596 ILE C CG1 1 
ATOM   12715 C CG2 . ILE C 1 536 ? -85.364  -16.130 26.784  1.00 51.56  ? 596 ILE C CG2 1 
ATOM   12716 C CD1 . ILE C 1 536 ? -84.568  -14.878 24.082  1.00 57.21  ? 596 ILE C CD1 1 
ATOM   12717 N N   . ALA C 1 537 ? -85.270  -13.712 29.568  1.00 46.20  ? 597 ALA C N   1 
ATOM   12718 C CA  . ALA C 1 537 ? -85.020  -14.046 30.978  1.00 50.88  ? 597 ALA C CA  1 
ATOM   12719 C C   . ALA C 1 537 ? -86.301  -13.771 31.787  1.00 60.42  ? 597 ALA C C   1 
ATOM   12720 O O   . ALA C 1 537 ? -86.785  -14.708 32.495  1.00 65.91  ? 597 ALA C O   1 
ATOM   12721 C CB  . ALA C 1 537 ? -83.824  -13.263 31.461  1.00 53.29  ? 597 ALA C CB  1 
ATOM   12722 N N   . ALA C 1 538 ? -86.849  -12.547 31.664  1.00 61.77  ? 598 ALA C N   1 
ATOM   12723 C CA  . ALA C 1 538 ? -88.039  -12.058 32.405  1.00 59.38  ? 598 ALA C CA  1 
ATOM   12724 C C   . ALA C 1 538 ? -89.188  -13.043 32.176  1.00 58.77  ? 598 ALA C C   1 
ATOM   12725 O O   . ALA C 1 538 ? -89.847  -13.411 33.167  1.00 54.81  ? 598 ALA C O   1 
ATOM   12726 C CB  . ALA C 1 538 ? -88.401  -10.641 31.993  1.00 52.52  ? 598 ALA C CB  1 
ATOM   12727 N N   . ALA C 1 539 ? -89.395  -13.474 30.927  1.00 53.27  ? 599 ALA C N   1 
ATOM   12728 C CA  . ALA C 1 539 ? -90.453  -14.437 30.546  1.00 59.27  ? 599 ALA C CA  1 
ATOM   12729 C C   . ALA C 1 539 ? -90.212  -15.810 31.182  1.00 57.75  ? 599 ALA C C   1 
ATOM   12730 O O   . ALA C 1 539 ? -91.167  -16.354 31.737  1.00 59.14  ? 599 ALA C O   1 
ATOM   12731 C CB  . ALA C 1 539 ? -90.522  -14.566 29.052  1.00 69.31  ? 599 ALA C CB  1 
ATOM   12732 N N   . VAL C 1 540 ? -89.001  -16.363 31.077  1.00 63.56  ? 600 VAL C N   1 
ATOM   12733 C CA  . VAL C 1 540 ? -88.688  -17.747 31.561  1.00 65.72  ? 600 VAL C CA  1 
ATOM   12734 C C   . VAL C 1 540 ? -88.755  -17.778 33.094  1.00 61.92  ? 600 VAL C C   1 
ATOM   12735 O O   . VAL C 1 540 ? -89.027  -18.869 33.661  1.00 65.37  ? 600 VAL C O   1 
ATOM   12736 C CB  . VAL C 1 540 ? -87.317  -18.243 31.071  1.00 60.29  ? 600 VAL C CB  1 
ATOM   12737 C CG1 . VAL C 1 540 ? -86.928  -19.529 31.773  1.00 60.61  ? 600 VAL C CG1 1 
ATOM   12738 C CG2 . VAL C 1 540 ? -87.275  -18.411 29.565  1.00 61.88  ? 600 VAL C CG2 1 
ATOM   12739 N N   . ALA C 1 541 ? -88.476  -16.638 33.726  1.00 61.74  ? 601 ALA C N   1 
ATOM   12740 C CA  . ALA C 1 541 ? -88.536  -16.446 35.194  1.00 66.64  ? 601 ALA C CA  1 
ATOM   12741 C C   . ALA C 1 541 ? -90.000  -16.388 35.619  1.00 65.35  ? 601 ALA C C   1 
ATOM   12742 O O   . ALA C 1 541 ? -90.393  -17.139 36.547  1.00 65.82  ? 601 ALA C O   1 
ATOM   12743 C CB  . ALA C 1 541 ? -87.794  -15.188 35.596  1.00 65.43  ? 601 ALA C CB  1 
ATOM   12744 N N   . ALA C 1 542 ? -90.778  -15.541 34.936  1.00 69.58  ? 602 ALA C N   1 
ATOM   12745 C CA  . ALA C 1 542 ? -92.233  -15.350 35.156  1.00 61.06  ? 602 ALA C CA  1 
ATOM   12746 C C   . ALA C 1 542 ? -92.912  -16.718 35.113  1.00 53.59  ? 602 ALA C C   1 
ATOM   12747 O O   . ALA C 1 542 ? -93.677  -17.018 36.039  1.00 63.49  ? 602 ALA C O   1 
ATOM   12748 C CB  . ALA C 1 542 ? -92.803  -14.387 34.136  1.00 56.74  ? 602 ALA C CB  1 
ATOM   12749 N N   . LYS C 1 543 ? -92.579  -17.532 34.108  1.00 54.82  ? 603 LYS C N   1 
ATOM   12750 C CA  . LYS C 1 543 ? -93.142  -18.893 33.910  1.00 59.58  ? 603 LYS C CA  1 
ATOM   12751 C C   . LYS C 1 543 ? -92.694  -19.798 35.054  1.00 58.47  ? 603 LYS C C   1 
ATOM   12752 O O   . LYS C 1 543 ? -93.484  -20.667 35.436  1.00 52.49  ? 603 LYS C O   1 
ATOM   12753 C CB  . LYS C 1 543 ? -92.694  -19.513 32.588  1.00 67.14  ? 603 LYS C CB  1 
ATOM   12754 C CG  . LYS C 1 543 ? -93.351  -20.839 32.260  1.00 76.04  ? 603 LYS C CG  1 
ATOM   12755 C CD  . LYS C 1 543 ? -94.863  -20.781 32.118  1.00 81.38  ? 603 LYS C CD  1 
ATOM   12756 C CE  . LYS C 1 543 ? -95.321  -20.045 30.881  1.00 71.24  ? 603 LYS C CE  1 
ATOM   12757 N NZ  . LYS C 1 543 ? -96.596  -19.352 31.146  1.00 75.79  ? 603 LYS C NZ  1 
ATOM   12758 N N   . ALA C 1 544 ? -91.472  -19.602 35.552  1.00 57.70  ? 604 ALA C N   1 
ATOM   12759 C CA  . ALA C 1 544 ? -90.883  -20.423 36.632  1.00 59.18  ? 604 ALA C CA  1 
ATOM   12760 C C   . ALA C 1 544 ? -91.693  -20.194 37.915  1.00 62.20  ? 604 ALA C C   1 
ATOM   12761 O O   . ALA C 1 544 ? -92.041  -21.213 38.572  1.00 56.89  ? 604 ALA C O   1 
ATOM   12762 C CB  . ALA C 1 544 ? -89.416  -20.103 36.786  1.00 60.96  ? 604 ALA C CB  1 
ATOM   12763 N N   . TYR C 1 545 ? -91.998  -18.917 38.213  1.00 59.74  ? 605 TYR C N   1 
ATOM   12764 C CA  . TYR C 1 545 ? -92.825  -18.457 39.363  1.00 55.90  ? 605 TYR C CA  1 
ATOM   12765 C C   . TYR C 1 545 ? -94.256  -18.995 39.221  1.00 55.69  ? 605 TYR C C   1 
ATOM   12766 O O   . TYR C 1 545 ? -94.719  -19.690 40.132  1.00 49.32  ? 605 TYR C O   1 
ATOM   12767 C CB  . TYR C 1 545 ? -92.837  -16.930 39.460  1.00 48.74  ? 605 TYR C CB  1 
ATOM   12768 C CG  . TYR C 1 545 ? -91.557  -16.331 39.971  1.00 49.15  ? 605 TYR C CG  1 
ATOM   12769 C CD1 . TYR C 1 545 ? -91.031  -16.710 41.190  1.00 56.60  ? 605 TYR C CD1 1 
ATOM   12770 C CD2 . TYR C 1 545 ? -90.879  -15.359 39.257  1.00 56.05  ? 605 TYR C CD2 1 
ATOM   12771 C CE1 . TYR C 1 545 ? -89.859  -16.154 41.687  1.00 63.95  ? 605 TYR C CE1 1 
ATOM   12772 C CE2 . TYR C 1 545 ? -89.703  -14.798 39.726  1.00 57.97  ? 605 TYR C CE2 1 
ATOM   12773 C CZ  . TYR C 1 545 ? -89.189  -15.190 40.950  1.00 62.30  ? 605 TYR C CZ  1 
ATOM   12774 O OH  . TYR C 1 545 ? -88.042  -14.607 41.417  1.00 53.01  ? 605 TYR C OH  1 
ATOM   12775 N N   . GLU C 1 546 ? -94.923  -18.680 38.109  1.00 53.45  ? 606 GLU C N   1 
ATOM   12776 C CA  . GLU C 1 546 ? -96.266  -19.199 37.750  1.00 55.22  ? 606 GLU C CA  1 
ATOM   12777 C C   . GLU C 1 546 ? -96.306  -20.722 38.012  1.00 54.04  ? 606 GLU C C   1 
ATOM   12778 O O   . GLU C 1 546 ? -97.101  -21.159 38.816  1.00 52.67  ? 606 GLU C O   1 
ATOM   12779 C CB  . GLU C 1 546 ? -96.569  -18.800 36.300  1.00 63.98  ? 606 GLU C CB  1 
ATOM   12780 C CG  . GLU C 1 546 ? -98.011  -19.016 35.848  1.00 75.82  ? 606 GLU C CG  1 
ATOM   12781 C CD  . GLU C 1 546 ? -98.205  -19.219 34.342  1.00 79.81  ? 606 GLU C CD  1 
ATOM   12782 O OE1 . GLU C 1 546 ? -97.592  -18.443 33.590  1.00 84.06  ? 606 GLU C OE1 1 
ATOM   12783 O OE2 . GLU C 1 546 ? -98.965  -20.161 33.929  1.00 71.83  ? 606 GLU C OE2 1 
ATOM   12784 N N   . LEU C 1 547 ? -95.443  -21.522 37.401  1.00 59.28  ? 607 LEU C N   1 
ATOM   12785 C CA  . LEU C 1 547 ? -95.389  -23.000 37.634  1.00 61.56  ? 607 LEU C CA  1 
ATOM   12786 C C   . LEU C 1 547 ? -94.957  -23.349 39.073  1.00 61.46  ? 607 LEU C C   1 
ATOM   12787 O O   . LEU C 1 547 ? -94.888  -24.576 39.377  1.00 51.15  ? 607 LEU C O   1 
ATOM   12788 C CB  . LEU C 1 547 ? -94.375  -23.621 36.668  1.00 60.38  ? 607 LEU C CB  1 
ATOM   12789 C CG  . LEU C 1 547 ? -94.832  -23.729 35.225  1.00 61.94  ? 607 LEU C CG  1 
ATOM   12790 C CD1 . LEU C 1 547 ? -93.637  -23.986 34.324  1.00 58.45  ? 607 LEU C CD1 1 
ATOM   12791 C CD2 . LEU C 1 547 ? -95.881  -24.812 35.084  1.00 65.88  ? 607 LEU C CD2 1 
ATOM   12792 N N   . GLY C 1 548 ? -94.592  -22.348 39.888  1.00 51.08  ? 608 GLY C N   1 
ATOM   12793 C CA  . GLY C 1 548 ? -94.042  -22.542 41.238  1.00 52.70  ? 608 GLY C CA  1 
ATOM   12794 C C   . GLY C 1 548 ? -92.879  -23.519 41.247  1.00 59.72  ? 608 GLY C C   1 
ATOM   12795 O O   . GLY C 1 548 ? -92.932  -24.533 41.995  1.00 62.37  ? 608 GLY C O   1 
ATOM   12796 N N   . LEU C 1 549 ? -91.859  -23.256 40.423  1.00 69.48  ? 609 LEU C N   1 
ATOM   12797 C CA  . LEU C 1 549 ? -90.553  -23.976 40.446  1.00 61.25  ? 609 LEU C CA  1 
ATOM   12798 C C   . LEU C 1 549 ? -89.422  -23.015 40.840  1.00 60.08  ? 609 LEU C C   1 
ATOM   12799 O O   . LEU C 1 549 ? -88.281  -23.506 41.026  1.00 53.83  ? 609 LEU C O   1 
ATOM   12800 C CB  . LEU C 1 549 ? -90.317  -24.604 39.070  1.00 61.87  ? 609 LEU C CB  1 
ATOM   12801 C CG  . LEU C 1 549 ? -91.282  -25.744 38.708  1.00 63.10  ? 609 LEU C CG  1 
ATOM   12802 C CD1 . LEU C 1 549 ? -91.300  -25.974 37.216  1.00 58.16  ? 609 LEU C CD1 1 
ATOM   12803 C CD2 . LEU C 1 549 ? -90.958  -27.049 39.449  1.00 60.75  ? 609 LEU C CD2 1 
ATOM   12804 N N   . ALA C 1 550 ? -89.721  -21.709 40.973  1.00 61.99  ? 610 ALA C N   1 
ATOM   12805 C CA  . ALA C 1 550 ? -88.769  -20.642 41.368  1.00 61.48  ? 610 ALA C CA  1 
ATOM   12806 C C   . ALA C 1 550 ? -88.529  -20.717 42.874  1.00 59.18  ? 610 ALA C C   1 
ATOM   12807 O O   . ALA C 1 550 ? -89.444  -21.198 43.556  1.00 60.20  ? 610 ALA C O   1 
ATOM   12808 C CB  . ALA C 1 550 ? -89.328  -19.295 40.996  1.00 62.96  ? 610 ALA C CB  1 
ATOM   12809 N N   . THR C 1 551 ? -87.350  -20.286 43.351  1.00 63.13  ? 611 THR C N   1 
ATOM   12810 C CA  . THR C 1 551 ? -86.976  -20.226 44.796  1.00 58.38  ? 611 THR C CA  1 
ATOM   12811 C C   . THR C 1 551 ? -86.468  -18.836 45.190  1.00 50.26  ? 611 THR C C   1 
ATOM   12812 O O   . THR C 1 551 ? -86.207  -18.682 46.365  1.00 47.34  ? 611 THR C O   1 
ATOM   12813 C CB  . THR C 1 551 ? -85.905  -21.251 45.209  1.00 60.89  ? 611 THR C CB  1 
ATOM   12814 O OG1 . THR C 1 551 ? -84.646  -20.797 44.707  1.00 67.54  ? 611 THR C OG1 1 
ATOM   12815 C CG2 . THR C 1 551 ? -86.181  -22.662 44.734  1.00 59.81  ? 611 THR C CG2 1 
ATOM   12816 N N   . ARG C 1 552 ? -86.315  -17.877 44.274  1.00 52.79  ? 612 ARG C N   1 
ATOM   12817 C CA  . ARG C 1 552 ? -86.009  -16.473 44.644  1.00 53.56  ? 612 ARG C CA  1 
ATOM   12818 C C   . ARG C 1 552 ? -87.335  -15.746 44.903  1.00 61.81  ? 612 ARG C C   1 
ATOM   12819 O O   . ARG C 1 552 ? -87.776  -15.026 43.990  1.00 66.85  ? 612 ARG C O   1 
ATOM   12820 C CB  . ARG C 1 552 ? -85.175  -15.800 43.551  1.00 59.00  ? 612 ARG C CB  1 
ATOM   12821 C CG  . ARG C 1 552 ? -83.753  -15.438 43.958  1.00 72.38  ? 612 ARG C CG  1 
ATOM   12822 C CD  . ARG C 1 552 ? -82.676  -15.847 42.962  1.00 83.30  ? 612 ARG C CD  1 
ATOM   12823 N NE  . ARG C 1 552 ? -81.469  -15.059 43.135  1.00 87.09  ? 612 ARG C NE  1 
ATOM   12824 C CZ  . ARG C 1 552 ? -80.569  -15.235 44.099  1.00 104.55 ? 612 ARG C CZ  1 
ATOM   12825 N NH1 . ARG C 1 552 ? -80.724  -16.193 45.002  1.00 114.91 ? 612 ARG C NH1 1 
ATOM   12826 N NH2 . ARG C 1 552 ? -79.513  -14.442 44.166  1.00 115.75 ? 612 ARG C NH2 1 
ATOM   12827 N N   . LEU C 1 553 ? -87.952  -15.961 46.073  1.00 60.82  ? 613 LEU C N   1 
ATOM   12828 C CA  . LEU C 1 553 ? -89.273  -15.368 46.447  1.00 56.84  ? 613 LEU C CA  1 
ATOM   12829 C C   . LEU C 1 553 ? -89.002  -14.134 47.302  1.00 62.75  ? 613 LEU C C   1 
ATOM   12830 O O   . LEU C 1 553 ? -88.029  -14.115 48.040  1.00 74.98  ? 613 LEU C O   1 
ATOM   12831 C CB  . LEU C 1 553 ? -90.131  -16.394 47.203  1.00 57.87  ? 613 LEU C CB  1 
ATOM   12832 C CG  . LEU C 1 553 ? -90.808  -17.503 46.389  1.00 61.41  ? 613 LEU C CG  1 
ATOM   12833 C CD1 . LEU C 1 553 ? -91.501  -16.960 45.147  1.00 64.22  ? 613 LEU C CD1 1 
ATOM   12834 C CD2 . LEU C 1 553 ? -89.823  -18.583 46.004  1.00 59.84  ? 613 LEU C CD2 1 
ATOM   12835 N N   . PRO C 1 554 ? -89.798  -13.043 47.227  1.00 74.57  ? 614 PRO C N   1 
ATOM   12836 C CA  . PRO C 1 554 ? -90.892  -12.912 46.262  1.00 78.28  ? 614 PRO C CA  1 
ATOM   12837 C C   . PRO C 1 554 ? -90.327  -12.560 44.888  1.00 75.66  ? 614 PRO C C   1 
ATOM   12838 O O   . PRO C 1 554 ? -89.191  -12.092 44.796  1.00 80.50  ? 614 PRO C O   1 
ATOM   12839 C CB  . PRO C 1 554 ? -91.735  -11.754 46.833  1.00 77.34  ? 614 PRO C CB  1 
ATOM   12840 C CG  . PRO C 1 554 ? -90.699  -10.881 47.538  1.00 75.13  ? 614 PRO C CG  1 
ATOM   12841 C CD  . PRO C 1 554 ? -89.665  -11.849 48.086  1.00 76.30  ? 614 PRO C CD  1 
ATOM   12842 N N   . PRO C 1 555 ? -91.097  -12.740 43.790  1.00 64.05  ? 615 PRO C N   1 
ATOM   12843 C CA  . PRO C 1 555 ? -90.658  -12.287 42.470  1.00 60.15  ? 615 PRO C CA  1 
ATOM   12844 C C   . PRO C 1 555 ? -90.557  -10.765 42.456  1.00 57.16  ? 615 PRO C C   1 
ATOM   12845 O O   . PRO C 1 555 ? -91.322  -10.073 43.112  1.00 58.89  ? 615 PRO C O   1 
ATOM   12846 C CB  . PRO C 1 555 ? -91.739  -12.768 41.498  1.00 61.70  ? 615 PRO C CB  1 
ATOM   12847 C CG  . PRO C 1 555 ? -92.953  -13.058 42.366  1.00 67.75  ? 615 PRO C CG  1 
ATOM   12848 C CD  . PRO C 1 555 ? -92.438  -13.345 43.768  1.00 66.52  ? 615 PRO C CD  1 
ATOM   12849 N N   . PRO C 1 556 ? -89.571  -10.187 41.757  1.00 57.03  ? 616 PRO C N   1 
ATOM   12850 C CA  . PRO C 1 556 ? -89.467  -8.735  41.665  1.00 64.59  ? 616 PRO C CA  1 
ATOM   12851 C C   . PRO C 1 556 ? -90.706  -8.162  40.982  1.00 65.59  ? 616 PRO C C   1 
ATOM   12852 O O   . PRO C 1 556 ? -91.353  -8.912  40.291  1.00 62.09  ? 616 PRO C O   1 
ATOM   12853 C CB  . PRO C 1 556 ? -88.232  -8.502  40.795  1.00 69.21  ? 616 PRO C CB  1 
ATOM   12854 C CG  . PRO C 1 556 ? -87.443  -9.803  40.931  1.00 70.70  ? 616 PRO C CG  1 
ATOM   12855 C CD  . PRO C 1 556 ? -88.475  -10.899 41.093  1.00 61.72  ? 616 PRO C CD  1 
ATOM   12856 N N   . SER C 1 557 ? -91.009  -6.879  41.207  1.00 75.07  ? 617 SER C N   1 
ATOM   12857 C CA  . SER C 1 557 ? -92.118  -6.157  40.526  1.00 80.08  ? 617 SER C CA  1 
ATOM   12858 C C   . SER C 1 557 ? -91.886  -6.199  39.007  1.00 82.11  ? 617 SER C C   1 
ATOM   12859 O O   . SER C 1 557 ? -92.778  -6.688  38.306  1.00 84.89  ? 617 SER C O   1 
ATOM   12860 C CB  . SER C 1 557 ? -92.267  -4.733  41.023  1.00 89.49  ? 617 SER C CB  1 
ATOM   12861 O OG  . SER C 1 557 ? -92.762  -4.701  42.357  1.00 97.01  ? 617 SER C OG  1 
ATOM   12862 N N   . ASP C 1 558 ? -90.698  -5.768  38.549  1.00 79.60  ? 618 ASP C N   1 
ATOM   12863 C CA  . ASP C 1 558 ? -90.322  -5.504  37.127  1.00 67.40  ? 618 ASP C CA  1 
ATOM   12864 C C   . ASP C 1 558 ? -89.252  -6.510  36.672  1.00 55.75  ? 618 ASP C C   1 
ATOM   12865 O O   . ASP C 1 558 ? -88.077  -6.142  36.680  1.00 59.41  ? 618 ASP C O   1 
ATOM   12866 C CB  . ASP C 1 558 ? -89.832  -4.054  36.978  1.00 66.38  ? 618 ASP C CB  1 
ATOM   12867 C CG  . ASP C 1 558 ? -89.607  -3.597  35.549  1.00 69.50  ? 618 ASP C CG  1 
ATOM   12868 O OD1 . ASP C 1 558 ? -89.598  -4.462  34.644  1.00 60.47  ? 618 ASP C OD1 1 
ATOM   12869 O OD2 . ASP C 1 558 ? -89.430  -2.374  35.358  1.00 76.58  ? 618 ASP C OD2 1 
ATOM   12870 N N   . LEU C 1 559 ? -89.651  -7.705  36.242  1.00 48.42  ? 619 LEU C N   1 
ATOM   12871 C CA  . LEU C 1 559 ? -88.740  -8.841  35.931  1.00 52.92  ? 619 LEU C CA  1 
ATOM   12872 C C   . LEU C 1 559 ? -87.741  -8.494  34.814  1.00 55.28  ? 619 LEU C C   1 
ATOM   12873 O O   . LEU C 1 559 ? -86.678  -9.126  34.762  1.00 60.95  ? 619 LEU C O   1 
ATOM   12874 C CB  . LEU C 1 559 ? -89.574  -10.059 35.509  1.00 54.75  ? 619 LEU C CB  1 
ATOM   12875 C CG  . LEU C 1 559 ? -89.900  -11.052 36.611  1.00 55.18  ? 619 LEU C CG  1 
ATOM   12876 C CD1 . LEU C 1 559 ? -90.560  -12.287 36.053  1.00 59.90  ? 619 LEU C CD1 1 
ATOM   12877 C CD2 . LEU C 1 559 ? -88.655  -11.444 37.378  1.00 56.82  ? 619 LEU C CD2 1 
ATOM   12878 N N   . VAL C 1 560 ? -88.074  -7.572  33.911  1.00 55.54  ? 620 VAL C N   1 
ATOM   12879 C CA  . VAL C 1 560 ? -87.155  -7.145  32.820  1.00 58.94  ? 620 VAL C CA  1 
ATOM   12880 C C   . VAL C 1 560 ? -86.020  -6.282  33.402  1.00 67.67  ? 620 VAL C C   1 
ATOM   12881 O O   . VAL C 1 560 ? -84.839  -6.621  33.149  1.00 78.98  ? 620 VAL C O   1 
ATOM   12882 C CB  . VAL C 1 560 ? -87.930  -6.449  31.683  1.00 58.60  ? 620 VAL C CB  1 
ATOM   12883 C CG1 . VAL C 1 560 ? -87.065  -5.511  30.835  1.00 57.94  ? 620 VAL C CG1 1 
ATOM   12884 C CG2 . VAL C 1 560 ? -88.607  -7.494  30.805  1.00 61.22  ? 620 VAL C CG2 1 
ATOM   12885 N N   . LYS C 1 561 ? -86.335  -5.213  34.144  1.00 65.69  ? 621 LYS C N   1 
ATOM   12886 C CA  . LYS C 1 561 ? -85.313  -4.292  34.711  1.00 62.94  ? 621 LYS C CA  1 
ATOM   12887 C C   . LYS C 1 561 ? -84.428  -5.054  35.712  1.00 56.82  ? 621 LYS C C   1 
ATOM   12888 O O   . LYS C 1 561 ? -83.264  -4.706  35.827  1.00 63.22  ? 621 LYS C O   1 
ATOM   12889 C CB  . LYS C 1 561 ? -85.981  -3.069  35.352  1.00 71.04  ? 621 LYS C CB  1 
ATOM   12890 C CG  . LYS C 1 561 ? -85.022  -1.925  35.669  1.00 84.45  ? 621 LYS C CG  1 
ATOM   12891 C CD  . LYS C 1 561 ? -85.687  -0.546  35.606  1.00 98.19  ? 621 LYS C CD  1 
ATOM   12892 C CE  . LYS C 1 561 ? -84.766  0.572   35.134  1.00 101.08 ? 621 LYS C CE  1 
ATOM   12893 N NZ  . LYS C 1 561 ? -85.378  1.906   35.352  1.00 94.54  ? 621 LYS C NZ  1 
ATOM   12894 N N   . TYR C 1 562 ? -84.946  -6.070  36.407  1.00 54.67  ? 622 TYR C N   1 
ATOM   12895 C CA  . TYR C 1 562 ? -84.171  -6.914  37.351  1.00 56.51  ? 622 TYR C CA  1 
ATOM   12896 C C   . TYR C 1 562 ? -83.155  -7.732  36.552  1.00 63.31  ? 622 TYR C C   1 
ATOM   12897 O O   . TYR C 1 562 ? -81.954  -7.714  36.899  1.00 77.72  ? 622 TYR C O   1 
ATOM   12898 C CB  . TYR C 1 562 ? -85.082  -7.815  38.196  1.00 55.25  ? 622 TYR C CB  1 
ATOM   12899 C CG  . TYR C 1 562 ? -84.391  -8.828  39.088  1.00 54.92  ? 622 TYR C CG  1 
ATOM   12900 C CD1 . TYR C 1 562 ? -83.635  -8.443  40.194  1.00 52.69  ? 622 TYR C CD1 1 
ATOM   12901 C CD2 . TYR C 1 562 ? -84.500  -10.192 38.837  1.00 53.05  ? 622 TYR C CD2 1 
ATOM   12902 C CE1 . TYR C 1 562 ? -82.994  -9.375  41.006  1.00 47.22  ? 622 TYR C CE1 1 
ATOM   12903 C CE2 . TYR C 1 562 ? -83.902  -11.140 39.659  1.00 48.85  ? 622 TYR C CE2 1 
ATOM   12904 C CZ  . TYR C 1 562 ? -83.144  -10.733 40.744  1.00 48.80  ? 622 TYR C CZ  1 
ATOM   12905 O OH  . TYR C 1 562 ? -82.547  -11.680 41.530  1.00 50.37  ? 622 TYR C OH  1 
ATOM   12906 N N   . ALA C 1 563 ? -83.616  -8.416  35.508  1.00 64.95  ? 623 ALA C N   1 
ATOM   12907 C CA  . ALA C 1 563 ? -82.776  -9.244  34.617  1.00 58.30  ? 623 ALA C CA  1 
ATOM   12908 C C   . ALA C 1 563 ? -81.651  -8.388  34.032  1.00 53.82  ? 623 ALA C C   1 
ATOM   12909 O O   . ALA C 1 563 ? -80.533  -8.903  33.975  1.00 58.16  ? 623 ALA C O   1 
ATOM   12910 C CB  . ALA C 1 563 ? -83.626  -9.862  33.532  1.00 64.85  ? 623 ALA C CB  1 
ATOM   12911 N N   . GLU C 1 564 ? -81.928  -7.139  33.618  1.00 58.00  ? 624 GLU C N   1 
ATOM   12912 C CA  . GLU C 1 564 ? -80.913  -6.215  33.028  1.00 60.84  ? 624 GLU C CA  1 
ATOM   12913 C C   . GLU C 1 564 ? -79.894  -5.797  34.093  1.00 64.28  ? 624 GLU C C   1 
ATOM   12914 O O   . GLU C 1 564 ? -78.735  -5.551  33.727  1.00 89.91  ? 624 GLU C O   1 
ATOM   12915 C CB  . GLU C 1 564 ? -81.528  -4.946  32.446  1.00 59.60  ? 624 GLU C CB  1 
ATOM   12916 C CG  . GLU C 1 564 ? -82.273  -5.176  31.153  1.00 63.44  ? 624 GLU C CG  1 
ATOM   12917 C CD  . GLU C 1 564 ? -83.164  -4.024  30.713  1.00 60.57  ? 624 GLU C CD  1 
ATOM   12918 O OE1 . GLU C 1 564 ? -83.426  -3.126  31.505  1.00 62.81  ? 624 GLU C OE1 1 
ATOM   12919 O OE2 . GLU C 1 564 ? -83.632  -4.056  29.593  1.00 67.08  ? 624 GLU C OE2 1 
ATOM   12920 N N   . ASN C 1 565 ? -80.309  -5.698  35.353  1.00 58.98  ? 625 ASN C N   1 
ATOM   12921 C CA  . ASN C 1 565 ? -79.449  -5.266  36.480  1.00 57.07  ? 625 ASN C CA  1 
ATOM   12922 C C   . ASN C 1 565 ? -78.598  -6.438  36.952  1.00 57.29  ? 625 ASN C C   1 
ATOM   12923 O O   . ASN C 1 565 ? -77.560  -6.166  37.520  1.00 71.17  ? 625 ASN C O   1 
ATOM   12924 C CB  . ASN C 1 565 ? -80.257  -4.642  37.622  1.00 58.60  ? 625 ASN C CB  1 
ATOM   12925 C CG  . ASN C 1 565 ? -80.726  -3.234  37.290  1.00 64.35  ? 625 ASN C CG  1 
ATOM   12926 O OD1 . ASN C 1 565 ? -80.189  -2.564  36.391  1.00 59.09  ? 625 ASN C OD1 1 
ATOM   12927 N ND2 . ASN C 1 565 ? -81.761  -2.785  37.987  1.00 65.61  ? 625 ASN C ND2 1 
ATOM   12928 N N   . CYS C 1 566 ? -78.999  -7.686  36.711  1.00 63.40  ? 626 CYS C N   1 
ATOM   12929 C CA  . CYS C 1 566 ? -78.206  -8.907  37.052  1.00 66.96  ? 626 CYS C CA  1 
ATOM   12930 C C   . CYS C 1 566 ? -77.148  -9.214  35.994  1.00 62.61  ? 626 CYS C C   1 
ATOM   12931 O O   . CYS C 1 566 ? -76.531  -10.286 36.091  1.00 75.60  ? 626 CYS C O   1 
ATOM   12932 C CB  . CYS C 1 566 ? -79.069  -10.156 37.135  1.00 66.11  ? 626 CYS C CB  1 
ATOM   12933 S SG  . CYS C 1 566 ? -80.128  -10.154 38.595  1.00 64.07  ? 626 CYS C SG  1 
ATOM   12934 N N   . MET C 1 567 ? -77.003  -8.371  34.976  1.00 60.12  ? 627 MET C N   1 
ATOM   12935 C CA  . MET C 1 567 ? -76.198  -8.713  33.778  1.00 61.29  ? 627 MET C CA  1 
ATOM   12936 C C   . MET C 1 567 ? -74.773  -8.220  33.998  1.00 60.82  ? 627 MET C C   1 
ATOM   12937 O O   . MET C 1 567 ? -74.581  -7.021  34.323  1.00 65.67  ? 627 MET C O   1 
ATOM   12938 C CB  . MET C 1 567 ? -76.779  -8.127  32.487  1.00 58.31  ? 627 MET C CB  1 
ATOM   12939 C CG  . MET C 1 567 ? -77.752  -9.066  31.788  1.00 58.57  ? 627 MET C CG  1 
ATOM   12940 S SD  . MET C 1 567 ? -78.489  -8.232  30.400  1.00 54.86  ? 627 MET C SD  1 
ATOM   12941 C CE  . MET C 1 567 ? -79.103  -9.608  29.441  1.00 61.04  ? 627 MET C CE  1 
ATOM   12942 N N   . TYR C 1 568 ? -73.823  -9.140  33.820  1.00 58.26  ? 628 TYR C N   1 
ATOM   12943 C CA  . TYR C 1 568 ? -72.371  -8.858  33.795  1.00 55.48  ? 628 TYR C CA  1 
ATOM   12944 C C   . TYR C 1 568 ? -72.118  -7.736  32.789  1.00 50.12  ? 628 TYR C C   1 
ATOM   12945 O O   . TYR C 1 568 ? -72.680  -7.774  31.713  1.00 49.53  ? 628 TYR C O   1 
ATOM   12946 C CB  . TYR C 1 568 ? -71.611  -10.137 33.458  1.00 53.85  ? 628 TYR C CB  1 
ATOM   12947 C CG  . TYR C 1 568 ? -70.154  -9.919  33.138  1.00 63.65  ? 628 TYR C CG  1 
ATOM   12948 C CD1 . TYR C 1 568 ? -69.727  -9.752  31.825  1.00 65.48  ? 628 TYR C CD1 1 
ATOM   12949 C CD2 . TYR C 1 568 ? -69.196  -9.900  34.137  1.00 58.37  ? 628 TYR C CD2 1 
ATOM   12950 C CE1 . TYR C 1 568 ? -68.389  -9.566  31.512  1.00 56.58  ? 628 TYR C CE1 1 
ATOM   12951 C CE2 . TYR C 1 568 ? -67.855  -9.719  33.840  1.00 59.48  ? 628 TYR C CE2 1 
ATOM   12952 C CZ  . TYR C 1 568 ? -67.451  -9.578  32.524  1.00 58.06  ? 628 TYR C CZ  1 
ATOM   12953 O OH  . TYR C 1 568 ? -66.131  -9.421  32.236  1.00 73.45  ? 628 TYR C OH  1 
ATOM   12954 N N   . THR C 1 569 ? -71.322  -6.745  33.143  1.00 51.36  ? 629 THR C N   1 
ATOM   12955 C CA  . THR C 1 569 ? -70.773  -5.764  32.166  1.00 60.86  ? 629 THR C CA  1 
ATOM   12956 C C   . THR C 1 569 ? -69.263  -5.972  32.136  1.00 65.10  ? 629 THR C C   1 
ATOM   12957 O O   . THR C 1 569 ? -68.627  -6.165  33.167  1.00 77.39  ? 629 THR C O   1 
ATOM   12958 C CB  . THR C 1 569 ? -71.161  -4.300  32.442  1.00 56.52  ? 629 THR C CB  1 
ATOM   12959 O OG1 . THR C 1 569 ? -71.302  -4.086  33.842  1.00 54.99  ? 629 THR C OG1 1 
ATOM   12960 C CG2 . THR C 1 569 ? -72.436  -3.868  31.754  1.00 61.95  ? 629 THR C CG2 1 
ATOM   12961 N N   . PRO C 1 570 ? -68.636  -6.008  30.951  1.00 57.62  ? 630 PRO C N   1 
ATOM   12962 C CA  . PRO C 1 570 ? -67.197  -6.178  30.871  1.00 56.52  ? 630 PRO C CA  1 
ATOM   12963 C C   . PRO C 1 570 ? -66.415  -4.856  30.832  1.00 53.37  ? 630 PRO C C   1 
ATOM   12964 O O   . PRO C 1 570 ? -65.234  -4.895  30.624  1.00 62.63  ? 630 PRO C O   1 
ATOM   12965 C CB  . PRO C 1 570 ? -67.080  -6.987  29.585  1.00 62.23  ? 630 PRO C CB  1 
ATOM   12966 C CG  . PRO C 1 570 ? -68.189  -6.456  28.710  1.00 64.18  ? 630 PRO C CG  1 
ATOM   12967 C CD  . PRO C 1 570 ? -69.266  -5.927  29.637  1.00 59.08  ? 630 PRO C CD  1 
ATOM   12968 N N   . VAL C 1 571 ? -67.053  -3.720  31.099  1.00 55.64  ? 631 VAL C N   1 
ATOM   12969 C CA  . VAL C 1 571 ? -66.336  -2.439  31.364  1.00 62.32  ? 631 VAL C CA  1 
ATOM   12970 C C   . VAL C 1 571 ? -65.289  -2.680  32.474  1.00 64.77  ? 631 VAL C C   1 
ATOM   12971 O O   . VAL C 1 571 ? -65.550  -3.470  33.413  1.00 61.71  ? 631 VAL C O   1 
ATOM   12972 C CB  . VAL C 1 571 ? -67.336  -1.318  31.704  1.00 66.50  ? 631 VAL C CB  1 
ATOM   12973 C CG1 . VAL C 1 571 ? -66.690  -0.141  32.412  1.00 76.62  ? 631 VAL C CG1 1 
ATOM   12974 C CG2 . VAL C 1 571 ? -68.063  -0.837  30.458  1.00 70.29  ? 631 VAL C CG2 1 
ATOM   12975 N N   . TYR C 1 572 ? -64.124  -2.035  32.372  1.00 62.75  ? 632 TYR C N   1 
ATOM   12976 C CA  . TYR C 1 572 ? -62.987  -2.210  33.320  1.00 60.41  ? 632 TYR C CA  1 
ATOM   12977 C C   . TYR C 1 572 ? -63.368  -1.745  34.725  1.00 61.66  ? 632 TYR C C   1 
ATOM   12978 O O   . TYR C 1 572 ? -63.848  -0.606  34.873  1.00 52.57  ? 632 TYR C O   1 
ATOM   12979 C CB  . TYR C 1 572 ? -61.718  -1.492  32.828  1.00 58.23  ? 632 TYR C CB  1 
ATOM   12980 C CG  . TYR C 1 572 ? -60.873  -2.261  31.831  1.00 51.45  ? 632 TYR C CG  1 
ATOM   12981 C CD1 . TYR C 1 572 ? -60.742  -3.664  31.886  1.00 49.66  ? 632 TYR C CD1 1 
ATOM   12982 C CD2 . TYR C 1 572 ? -60.206  -1.584  30.830  1.00 42.26  ? 632 TYR C CD2 1 
ATOM   12983 C CE1 . TYR C 1 572 ? -59.986  -4.368  30.969  1.00 39.02  ? 632 TYR C CE1 1 
ATOM   12984 C CE2 . TYR C 1 572 ? -59.426  -2.278  29.918  1.00 47.38  ? 632 TYR C CE2 1 
ATOM   12985 C CZ  . TYR C 1 572 ? -59.306  -3.665  29.994  1.00 41.82  ? 632 TYR C CZ  1 
ATOM   12986 O OH  . TYR C 1 572 ? -58.516  -4.308  29.090  1.00 38.81  ? 632 TYR C OH  1 
ATOM   12987 N N   . ARG C 1 573 ? -63.127  -2.644  35.688  1.00 72.77  ? 633 ARG C N   1 
ATOM   12988 C CA  . ARG C 1 573 ? -63.128  -2.472  37.164  1.00 79.01  ? 633 ARG C CA  1 
ATOM   12989 C C   . ARG C 1 573 ? -62.080  -1.426  37.573  1.00 73.56  ? 633 ARG C C   1 
ATOM   12990 O O   . ARG C 1 573 ? -61.033  -1.369  36.915  1.00 80.19  ? 633 ARG C O   1 
ATOM   12991 C CB  . ARG C 1 573 ? -62.796  -3.849  37.770  1.00 90.81  ? 633 ARG C CB  1 
ATOM   12992 C CG  . ARG C 1 573 ? -63.885  -4.522  38.603  1.00 93.11  ? 633 ARG C CG  1 
ATOM   12993 C CD  . ARG C 1 573 ? -65.333  -4.258  38.242  1.00 94.39  ? 633 ARG C CD  1 
ATOM   12994 N NE  . ARG C 1 573 ? -66.126  -3.874  39.415  1.00 95.79  ? 633 ARG C NE  1 
ATOM   12995 C CZ  . ARG C 1 573 ? -66.425  -4.671  40.438  1.00 90.98  ? 633 ARG C CZ  1 
ATOM   12996 N NH1 . ARG C 1 573 ? -67.176  -4.208  41.425  1.00 91.46  ? 633 ARG C NH1 1 
ATOM   12997 N NH2 . ARG C 1 573 ? -65.994  -5.926  40.465  1.00 94.27  ? 633 ARG C NH2 1 
ATOM   12998 N N   . ASN C 1 574 ? -62.350  -0.644  38.614  1.00 76.07  ? 634 ASN C N   1 
ATOM   12999 C CA  . ASN C 1 574 ? -61.420  0.408   39.110  1.00 88.79  ? 634 ASN C CA  1 
ATOM   13000 C C   . ASN C 1 574 ? -60.700  -0.103  40.360  1.00 79.66  ? 634 ASN C C   1 
ATOM   13001 O O   . ASN C 1 574 ? -61.383  -0.491  41.322  1.00 69.39  ? 634 ASN C O   1 
ATOM   13002 C CB  . ASN C 1 574 ? -62.104  1.761   39.357  1.00 93.11  ? 634 ASN C CB  1 
ATOM   13003 C CG  . ASN C 1 574 ? -61.157  2.900   39.043  1.00 99.73  ? 634 ASN C CG  1 
ATOM   13004 O OD1 . ASN C 1 574 ? -60.605  3.513   39.970  1.00 88.74  ? 634 ASN C OD1 1 
ATOM   13005 N ND2 . ASN C 1 574 ? -60.893  3.094   37.750  1.00 99.58  ? 634 ASN C ND2 1 
ATOM   13006 N N   . TYR C 1 575 ? -59.358  -0.055  40.355  1.00 87.05  ? 635 TYR C N   1 
ATOM   13007 C CA  . TYR C 1 575 ? -58.468  -0.528  41.455  1.00 80.41  ? 635 TYR C CA  1 
ATOM   13008 C C   . TYR C 1 575 ? -57.749  0.687   42.072  1.00 78.77  ? 635 TYR C C   1 
ATOM   13009 O O   . TYR C 1 575 ? -56.697  0.990   41.594  1.00 64.42  ? 635 TYR C O   1 
ATOM   13010 C CB  . TYR C 1 575 ? -57.489  -1.572  40.911  1.00 67.88  ? 635 TYR C CB  1 
ATOM   13011 C CG  . TYR C 1 575 ? -58.119  -2.750  40.212  1.00 61.56  ? 635 TYR C CG  1 
ATOM   13012 C CD1 . TYR C 1 575 ? -58.798  -3.712  40.929  1.00 70.51  ? 635 TYR C CD1 1 
ATOM   13013 C CD2 . TYR C 1 575 ? -58.023  -2.930  38.842  1.00 62.80  ? 635 TYR C CD2 1 
ATOM   13014 C CE1 . TYR C 1 575 ? -59.380  -4.809  40.314  1.00 69.21  ? 635 TYR C CE1 1 
ATOM   13015 C CE2 . TYR C 1 575 ? -58.584  -4.029  38.206  1.00 64.15  ? 635 TYR C CE2 1 
ATOM   13016 C CZ  . TYR C 1 575 ? -59.269  -4.975  38.951  1.00 64.08  ? 635 TYR C CZ  1 
ATOM   13017 O OH  . TYR C 1 575 ? -59.838  -6.079  38.397  1.00 63.01  ? 635 TYR C OH  1 
ATOM   13018 N N   . ARG C 1 576 ? -58.316  1.369   43.085  1.00 95.43  ? 636 ARG C N   1 
ATOM   13019 C CA  . ARG C 1 576 ? -58.085  2.809   43.435  1.00 91.40  ? 636 ARG C CA  1 
ATOM   13020 C C   . ARG C 1 576 ? -58.169  3.644   42.154  1.00 76.17  ? 636 ARG C C   1 
ATOM   13021 O O   . ARG C 1 576 ? -57.357  4.545   42.050  1.00 63.50  ? 636 ARG C O   1 
ATOM   13022 C CB  . ARG C 1 576 ? -56.753  3.086   44.155  1.00 108.49 ? 636 ARG C CB  1 
ATOM   13023 C CG  . ARG C 1 576 ? -55.623  2.108   43.849  1.00 124.14 ? 636 ARG C CG  1 
ATOM   13024 C CD  . ARG C 1 576 ? -54.221  2.687   43.985  1.00 122.86 ? 636 ARG C CD  1 
ATOM   13025 N NE  . ARG C 1 576 ? -53.592  2.502   45.287  1.00 120.25 ? 636 ARG C NE  1 
ATOM   13026 C CZ  . ARG C 1 576 ? -53.186  1.332   45.783  1.00 119.92 ? 636 ARG C CZ  1 
ATOM   13027 N NH1 . ARG C 1 576 ? -53.380  0.216   45.099  1.00 125.86 ? 636 ARG C NH1 1 
ATOM   13028 N NH2 . ARG C 1 576 ? -52.594  1.287   46.966  1.00 113.26 ? 636 ARG C NH2 1 
ATOM   13029 N N   . GLU D 1 12  ? -7.547   -6.259  47.807  1.00 121.43 ? 72  GLU D N   1 
ATOM   13030 C CA  . GLU D 1 12  ? -8.939   -5.750  47.876  1.00 117.98 ? 72  GLU D CA  1 
ATOM   13031 C C   . GLU D 1 12  ? -9.807   -6.635  46.960  1.00 136.61 ? 72  GLU D C   1 
ATOM   13032 O O   . GLU D 1 12  ? -9.931   -7.847  47.281  1.00 135.41 ? 72  GLU D O   1 
ATOM   13033 C CB  . GLU D 1 12  ? -8.940   -4.243  47.579  1.00 110.37 ? 72  GLU D CB  1 
ATOM   13034 C CG  . GLU D 1 12  ? -8.468   -3.376  48.748  1.00 106.06 ? 72  GLU D CG  1 
ATOM   13035 C CD  . GLU D 1 12  ? -6.968   -3.097  48.867  1.00 109.42 ? 72  GLU D CD  1 
ATOM   13036 O OE1 . GLU D 1 12  ? -6.152   -3.920  48.417  1.00 106.01 ? 72  GLU D OE1 1 
ATOM   13037 O OE2 . GLU D 1 12  ? -6.598   -2.052  49.432  1.00 103.49 ? 72  GLU D OE2 1 
ATOM   13038 N N   . LYS D 1 13  ? -10.342  -6.088  45.851  1.00 138.21 ? 73  LYS D N   1 
ATOM   13039 C CA  . LYS D 1 13  ? -11.272  -6.742  44.869  1.00 141.96 ? 73  LYS D CA  1 
ATOM   13040 C C   . LYS D 1 13  ? -12.709  -6.782  45.425  1.00 136.78 ? 73  LYS D C   1 
ATOM   13041 O O   . LYS D 1 13  ? -13.569  -6.119  44.816  1.00 141.92 ? 73  LYS D O   1 
ATOM   13042 C CB  . LYS D 1 13  ? -10.808  -8.139  44.417  1.00 149.19 ? 73  LYS D CB  1 
ATOM   13043 C CG  . LYS D 1 13  ? -9.683   -8.197  43.372  1.00 146.55 ? 73  LYS D CG  1 
ATOM   13044 C CD  . LYS D 1 13  ? -10.089  -7.869  41.928  1.00 140.70 ? 73  LYS D CD  1 
ATOM   13045 C CE  . LYS D 1 13  ? -9.228   -8.549  40.872  1.00 120.51 ? 73  LYS D CE  1 
ATOM   13046 N NZ  . LYS D 1 13  ? -9.184   -7.798  39.589  1.00 104.68 ? 73  LYS D NZ  1 
ATOM   13047 N N   . GLU D 1 14  ? -12.965  -7.526  46.510  1.00 138.15 ? 74  GLU D N   1 
ATOM   13048 C CA  . GLU D 1 14  ? -14.283  -7.601  47.211  1.00 125.81 ? 74  GLU D CA  1 
ATOM   13049 C C   . GLU D 1 14  ? -14.525  -6.308  48.022  1.00 128.95 ? 74  GLU D C   1 
ATOM   13050 O O   . GLU D 1 14  ? -14.346  -6.324  49.271  1.00 110.66 ? 74  GLU D O   1 
ATOM   13051 C CB  . GLU D 1 14  ? -14.351  -8.837  48.117  1.00 127.31 ? 74  GLU D CB  1 
ATOM   13052 C CG  . GLU D 1 14  ? -14.489  -10.165 47.390  1.00 115.84 ? 74  GLU D CG  1 
ATOM   13053 C CD  . GLU D 1 14  ? -13.221  -11.005 47.433  1.00 126.01 ? 74  GLU D CD  1 
ATOM   13054 O OE1 . GLU D 1 14  ? -12.166  -10.489 46.991  1.00 124.62 ? 74  GLU D OE1 1 
ATOM   13055 O OE2 . GLU D 1 14  ? -13.281  -12.163 47.944  1.00 116.47 ? 74  GLU D OE2 1 
ATOM   13056 N N   . GLN D 1 15  ? -14.912  -5.213  47.348  1.00 145.17 ? 75  GLN D N   1 
ATOM   13057 C CA  . GLN D 1 15  ? -15.308  -3.923  47.996  1.00 131.26 ? 75  GLN D CA  1 
ATOM   13058 C C   . GLN D 1 15  ? -16.793  -4.010  48.336  1.00 121.88 ? 75  GLN D C   1 
ATOM   13059 O O   . GLN D 1 15  ? -17.614  -3.455  47.580  1.00 111.11 ? 75  GLN D O   1 
ATOM   13060 C CB  . GLN D 1 15  ? -15.053  -2.696  47.114  1.00 126.66 ? 75  GLN D CB  1 
ATOM   13061 C CG  . GLN D 1 15  ? -13.708  -2.702  46.404  1.00 136.73 ? 75  GLN D CG  1 
ATOM   13062 C CD  . GLN D 1 15  ? -12.554  -2.985  47.335  1.00 147.92 ? 75  GLN D CD  1 
ATOM   13063 O OE1 . GLN D 1 15  ? -12.222  -2.182  48.206  1.00 143.45 ? 75  GLN D OE1 1 
ATOM   13064 N NE2 . GLN D 1 15  ? -11.927  -4.137  47.142  1.00 146.19 ? 75  GLN D NE2 1 
ATOM   13065 N N   . GLU D 1 16  ? -17.110  -4.689  49.442  1.00 109.65 ? 76  GLU D N   1 
ATOM   13066 C CA  . GLU D 1 16  ? -18.478  -4.853  49.988  1.00 80.09  ? 76  GLU D CA  1 
ATOM   13067 C C   . GLU D 1 16  ? -18.840  -3.628  50.832  1.00 85.58  ? 76  GLU D C   1 
ATOM   13068 O O   . GLU D 1 16  ? -19.767  -3.746  51.636  1.00 80.41  ? 76  GLU D O   1 
ATOM   13069 C CB  . GLU D 1 16  ? -18.500  -6.099  50.858  1.00 67.52  ? 76  GLU D CB  1 
ATOM   13070 C CG  . GLU D 1 16  ? -19.884  -6.598  51.163  1.00 69.32  ? 76  GLU D CG  1 
ATOM   13071 C CD  . GLU D 1 16  ? -19.962  -8.110  51.051  1.00 75.38  ? 76  GLU D CD  1 
ATOM   13072 O OE1 . GLU D 1 16  ? -18.949  -8.714  50.623  1.00 79.77  ? 76  GLU D OE1 1 
ATOM   13073 O OE2 . GLU D 1 16  ? -21.019  -8.684  51.371  1.00 63.62  ? 76  GLU D OE2 1 
ATOM   13074 N N   . GLU D 1 17  ? -18.098  -2.522  50.673  1.00 93.20  ? 77  GLU D N   1 
ATOM   13075 C CA  . GLU D 1 17  ? -18.318  -1.238  51.390  1.00 101.81 ? 77  GLU D CA  1 
ATOM   13076 C C   . GLU D 1 17  ? -19.594  -0.596  50.849  1.00 100.58 ? 77  GLU D C   1 
ATOM   13077 O O   . GLU D 1 17  ? -20.391  -0.088  51.665  1.00 92.11  ? 77  GLU D O   1 
ATOM   13078 C CB  . GLU D 1 17  ? -17.123  -0.294  51.213  1.00 111.53 ? 77  GLU D CB  1 
ATOM   13079 C CG  . GLU D 1 17  ? -15.979  -0.536  52.188  1.00 102.14 ? 77  GLU D CG  1 
ATOM   13080 C CD  . GLU D 1 17  ? -14.691  0.136   51.750  1.00 108.81 ? 77  GLU D CD  1 
ATOM   13081 O OE1 . GLU D 1 17  ? -14.378  0.071   50.539  1.00 115.97 ? 77  GLU D OE1 1 
ATOM   13082 O OE2 . GLU D 1 17  ? -14.020  0.736   52.602  1.00 111.46 ? 77  GLU D OE2 1 
ATOM   13083 N N   . ALA D 1 18  ? -19.778  -0.651  49.524  1.00 111.33 ? 78  ALA D N   1 
ATOM   13084 C CA  . ALA D 1 18  ? -20.939  -0.082  48.794  1.00 119.38 ? 78  ALA D CA  1 
ATOM   13085 C C   . ALA D 1 18  ? -22.172  -1.002  48.917  1.00 118.86 ? 78  ALA D C   1 
ATOM   13086 O O   . ALA D 1 18  ? -23.288  -0.494  48.650  1.00 129.27 ? 78  ALA D O   1 
ATOM   13087 C CB  . ALA D 1 18  ? -20.557  0.174   47.356  1.00 113.59 ? 78  ALA D CB  1 
ATOM   13088 N N   . ALA D 1 19  ? -22.000  -2.276  49.328  1.00 107.69 ? 79  ALA D N   1 
ATOM   13089 C CA  . ALA D 1 19  ? -23.078  -3.289  49.524  1.00 95.47  ? 79  ALA D CA  1 
ATOM   13090 C C   . ALA D 1 19  ? -23.651  -3.231  50.955  1.00 100.82 ? 79  ALA D C   1 
ATOM   13091 O O   . ALA D 1 19  ? -24.799  -3.671  51.138  1.00 116.62 ? 79  ALA D O   1 
ATOM   13092 C CB  . ALA D 1 19  ? -22.580  -4.684  49.187  1.00 84.43  ? 79  ALA D CB  1 
ATOM   13093 N N   . ALA D 1 20  ? -22.883  -2.746  51.934  1.00 102.69 ? 80  ALA D N   1 
ATOM   13094 C CA  . ALA D 1 20  ? -23.332  -2.495  53.323  1.00 89.28  ? 80  ALA D CA  1 
ATOM   13095 C C   . ALA D 1 20  ? -23.591  -0.992  53.498  1.00 94.42  ? 80  ALA D C   1 
ATOM   13096 O O   . ALA D 1 20  ? -23.599  -0.539  54.652  1.00 90.61  ? 80  ALA D O   1 
ATOM   13097 C CB  . ALA D 1 20  ? -22.303  -3.014  54.314  1.00 84.17  ? 80  ALA D CB  1 
ATOM   13098 N N   . ALA D 1 21  ? -23.709  -0.245  52.391  1.00 97.81  ? 81  ALA D N   1 
ATOM   13099 C CA  . ALA D 1 21  ? -24.333  1.096   52.309  1.00 104.49 ? 81  ALA D CA  1 
ATOM   13100 C C   . ALA D 1 21  ? -25.665  0.988   51.532  1.00 116.59 ? 81  ALA D C   1 
ATOM   13101 O O   . ALA D 1 21  ? -26.141  2.016   51.044  1.00 121.80 ? 81  ALA D O   1 
ATOM   13102 C CB  . ALA D 1 21  ? -23.362  2.070   51.687  1.00 100.90 ? 81  ALA D CB  1 
ATOM   13103 N N   . SER D 1 22  ? -26.232  -0.229  51.428  1.00 116.95 ? 82  SER D N   1 
ATOM   13104 C CA  . SER D 1 22  ? -27.608  -0.547  50.954  1.00 106.79 ? 82  SER D CA  1 
ATOM   13105 C C   . SER D 1 22  ? -28.512  -0.754  52.182  1.00 101.21 ? 82  SER D C   1 
ATOM   13106 O O   . SER D 1 22  ? -28.866  -1.913  52.511  1.00 85.92  ? 82  SER D O   1 
ATOM   13107 C CB  . SER D 1 22  ? -27.615  -1.750  50.001  1.00 109.95 ? 82  SER D CB  1 
ATOM   13108 O OG  . SER D 1 22  ? -27.674  -3.009  50.677  1.00 93.27  ? 82  SER D OG  1 
ATOM   13109 N N   . GLU D 1 23  ? -28.861  0.335   52.862  1.00 104.27 ? 83  GLU D N   1 
ATOM   13110 C CA  . GLU D 1 23  ? -29.717  0.289   54.081  1.00 110.02 ? 83  GLU D CA  1 
ATOM   13111 C C   . GLU D 1 23  ? -31.043  1.028   53.818  1.00 102.11 ? 83  GLU D C   1 
ATOM   13112 O O   . GLU D 1 23  ? -32.092  0.408   54.090  1.00 91.29  ? 83  GLU D O   1 
ATOM   13113 C CB  . GLU D 1 23  ? -28.925  0.772   55.302  1.00 128.16 ? 83  GLU D CB  1 
ATOM   13114 C CG  . GLU D 1 23  ? -29.085  2.260   55.659  1.00 141.24 ? 83  GLU D CG  1 
ATOM   13115 C CD  . GLU D 1 23  ? -28.043  3.199   55.069  1.00 133.97 ? 83  GLU D CD  1 
ATOM   13116 O OE1 . GLU D 1 23  ? -27.442  2.851   54.030  1.00 149.26 ? 83  GLU D OE1 1 
ATOM   13117 O OE2 . GLU D 1 23  ? -27.832  4.281   55.660  1.00 109.35 ? 83  GLU D OE2 1 
ATOM   13118 N N   . GLU D 1 24  ? -31.004  2.260   53.271  1.00 99.96  ? 84  GLU D N   1 
ATOM   13119 C CA  . GLU D 1 24  ? -32.189  2.993   52.726  1.00 97.54  ? 84  GLU D CA  1 
ATOM   13120 C C   . GLU D 1 24  ? -32.350  2.695   51.223  1.00 101.31 ? 84  GLU D C   1 
ATOM   13121 O O   . GLU D 1 24  ? -32.945  3.520   50.500  1.00 96.09  ? 84  GLU D O   1 
ATOM   13122 C CB  . GLU D 1 24  ? -32.099  4.512   52.891  1.00 95.08  ? 84  GLU D CB  1 
ATOM   13123 C CG  . GLU D 1 24  ? -32.530  5.020   54.260  1.00 99.18  ? 84  GLU D CG  1 
ATOM   13124 C CD  . GLU D 1 24  ? -31.385  5.534   55.107  1.00 104.97 ? 84  GLU D CD  1 
ATOM   13125 O OE1 . GLU D 1 24  ? -30.356  5.926   54.520  1.00 116.54 ? 84  GLU D OE1 1 
ATOM   13126 O OE2 . GLU D 1 24  ? -31.524  5.562   56.351  1.00 99.25  ? 84  GLU D OE2 1 
ATOM   13127 N N   . LEU D 1 25  ? -31.847  1.550   50.756  1.00 98.52  ? 85  LEU D N   1 
ATOM   13128 C CA  . LEU D 1 25  ? -32.155  1.019   49.403  1.00 93.68  ? 85  LEU D CA  1 
ATOM   13129 C C   . LEU D 1 25  ? -33.628  0.617   49.381  1.00 98.47  ? 85  LEU D C   1 
ATOM   13130 O O   . LEU D 1 25  ? -34.048  -0.150  50.245  1.00 88.78  ? 85  LEU D O   1 
ATOM   13131 C CB  . LEU D 1 25  ? -31.241  -0.183  49.124  1.00 86.55  ? 85  LEU D CB  1 
ATOM   13132 C CG  . LEU D 1 25  ? -31.104  -0.563  47.651  1.00 84.36  ? 85  LEU D CG  1 
ATOM   13133 C CD1 . LEU D 1 25  ? -30.113  0.362   46.953  1.00 85.00  ? 85  LEU D CD1 1 
ATOM   13134 C CD2 . LEU D 1 25  ? -30.708  -2.027  47.484  1.00 81.60  ? 85  LEU D CD2 1 
ATOM   13135 N N   . PRO D 1 26  ? -34.475  1.109   48.438  1.00 101.87 ? 86  PRO D N   1 
ATOM   13136 C CA  . PRO D 1 26  ? -35.803  0.528   48.255  1.00 86.92  ? 86  PRO D CA  1 
ATOM   13137 C C   . PRO D 1 26  ? -35.662  -0.995  48.075  1.00 71.40  ? 86  PRO D C   1 
ATOM   13138 O O   . PRO D 1 26  ? -34.782  -1.425  47.387  1.00 62.19  ? 86  PRO D O   1 
ATOM   13139 C CB  . PRO D 1 26  ? -36.362  1.235   46.998  1.00 80.98  ? 86  PRO D CB  1 
ATOM   13140 C CG  . PRO D 1 26  ? -35.606  2.537   46.924  1.00 86.39  ? 86  PRO D CG  1 
ATOM   13141 C CD  . PRO D 1 26  ? -34.237  2.228   47.507  1.00 94.10  ? 86  PRO D CD  1 
ATOM   13142 N N   . VAL D 1 27  ? -36.503  -1.790  48.729  1.00 71.61  ? 87  VAL D N   1 
ATOM   13143 C CA  . VAL D 1 27  ? -36.587  -3.257  48.455  1.00 69.08  ? 87  VAL D CA  1 
ATOM   13144 C C   . VAL D 1 27  ? -38.064  -3.658  48.424  1.00 61.51  ? 87  VAL D C   1 
ATOM   13145 O O   . VAL D 1 27  ? -38.933  -2.977  49.007  1.00 63.48  ? 87  VAL D O   1 
ATOM   13146 C CB  . VAL D 1 27  ? -35.793  -4.084  49.480  1.00 65.30  ? 87  VAL D CB  1 
ATOM   13147 C CG1 . VAL D 1 27  ? -34.308  -3.776  49.415  1.00 70.55  ? 87  VAL D CG1 1 
ATOM   13148 C CG2 . VAL D 1 27  ? -36.323  -3.890  50.899  1.00 61.74  ? 87  VAL D CG2 1 
ATOM   13149 N N   . MET D 1 28  ? -38.356  -4.746  47.739  1.00 55.45  ? 88  MET D N   1 
ATOM   13150 C CA  . MET D 1 28  ? -39.719  -5.298  47.629  1.00 59.21  ? 88  MET D CA  1 
ATOM   13151 C C   . MET D 1 28  ? -39.772  -6.506  48.552  1.00 61.11  ? 88  MET D C   1 
ATOM   13152 O O   . MET D 1 28  ? -38.896  -7.358  48.475  1.00 65.94  ? 88  MET D O   1 
ATOM   13153 C CB  . MET D 1 28  ? -39.976  -5.737  46.188  1.00 72.23  ? 88  MET D CB  1 
ATOM   13154 C CG  . MET D 1 28  ? -41.366  -6.249  45.912  1.00 76.64  ? 88  MET D CG  1 
ATOM   13155 S SD  . MET D 1 28  ? -42.708  -5.057  45.646  1.00 78.90  ? 88  MET D SD  1 
ATOM   13156 C CE  . MET D 1 28  ? -41.891  -3.476  45.558  1.00 84.76  ? 88  MET D CE  1 
ATOM   13157 N N   . PRO D 1 29  ? -40.766  -6.608  49.468  1.00 52.70  ? 89  PRO D N   1 
ATOM   13158 C CA  . PRO D 1 29  ? -40.955  -7.828  50.258  1.00 48.79  ? 89  PRO D CA  1 
ATOM   13159 C C   . PRO D 1 29  ? -41.525  -9.013  49.460  1.00 44.17  ? 89  PRO D C   1 
ATOM   13160 O O   . PRO D 1 29  ? -42.662  -9.147  49.390  1.00 47.58  ? 89  PRO D O   1 
ATOM   13161 C CB  . PRO D 1 29  ? -41.914  -7.357  51.353  1.00 45.66  ? 89  PRO D CB  1 
ATOM   13162 C CG  . PRO D 1 29  ? -42.713  -6.270  50.692  1.00 44.92  ? 89  PRO D CG  1 
ATOM   13163 C CD  . PRO D 1 29  ? -41.749  -5.564  49.775  1.00 42.85  ? 89  PRO D CD  1 
ATOM   13164 N N   . TRP D 1 30  ? -40.668  -9.827  48.865  1.00 52.46  ? 90  TRP D N   1 
ATOM   13165 C CA  . TRP D 1 30  ? -41.029  -11.018 48.041  1.00 56.29  ? 90  TRP D CA  1 
ATOM   13166 C C   . TRP D 1 30  ? -41.533  -12.107 48.988  1.00 50.43  ? 90  TRP D C   1 
ATOM   13167 O O   . TRP D 1 30  ? -40.974  -12.234 50.075  1.00 53.07  ? 90  TRP D O   1 
ATOM   13168 C CB  . TRP D 1 30  ? -39.843  -11.513 47.167  1.00 62.70  ? 90  TRP D CB  1 
ATOM   13169 C CG  . TRP D 1 30  ? -39.377  -10.464 46.204  1.00 58.81  ? 90  TRP D CG  1 
ATOM   13170 C CD1 . TRP D 1 30  ? -38.291  -9.647  46.315  1.00 58.44  ? 90  TRP D CD1 1 
ATOM   13171 C CD2 . TRP D 1 30  ? -40.085  -10.028 45.040  1.00 60.57  ? 90  TRP D CD2 1 
ATOM   13172 N NE1 . TRP D 1 30  ? -38.287  -8.716  45.313  1.00 57.12  ? 90  TRP D NE1 1 
ATOM   13173 C CE2 . TRP D 1 30  ? -39.394  -8.907  44.537  1.00 58.69  ? 90  TRP D CE2 1 
ATOM   13174 C CE3 . TRP D 1 30  ? -41.270  -10.434 44.416  1.00 65.32  ? 90  TRP D CE3 1 
ATOM   13175 C CZ2 . TRP D 1 30  ? -39.818  -8.238  43.392  1.00 62.42  ? 90  TRP D CZ2 1 
ATOM   13176 C CZ3 . TRP D 1 30  ? -41.695  -9.759  43.291  1.00 65.00  ? 90  TRP D CZ3 1 
ATOM   13177 C CH2 . TRP D 1 30  ? -40.974  -8.678  42.785  1.00 58.32  ? 90  TRP D CH2 1 
ATOM   13178 N N   . ALA D 1 31  ? -42.577  -12.831 48.619  1.00 48.25  ? 91  ALA D N   1 
ATOM   13179 C CA  . ALA D 1 31  ? -42.970  -14.077 49.316  1.00 58.85  ? 91  ALA D CA  1 
ATOM   13180 C C   . ALA D 1 31  ? -42.755  -15.265 48.374  1.00 52.98  ? 91  ALA D C   1 
ATOM   13181 O O   . ALA D 1 31  ? -43.076  -15.128 47.195  1.00 51.29  ? 91  ALA D O   1 
ATOM   13182 C CB  . ALA D 1 31  ? -44.405  -13.958 49.746  1.00 66.91  ? 91  ALA D CB  1 
ATOM   13183 N N   . THR D 1 32  ? -42.220  -16.372 48.863  1.00 52.61  ? 92  THR D N   1 
ATOM   13184 C CA  . THR D 1 32  ? -42.040  -17.609 48.054  1.00 62.96  ? 92  THR D CA  1 
ATOM   13185 C C   . THR D 1 32  ? -43.090  -18.643 48.467  1.00 55.76  ? 92  THR D C   1 
ATOM   13186 O O   . THR D 1 32  ? -43.270  -18.846 49.659  1.00 64.49  ? 92  THR D O   1 
ATOM   13187 C CB  . THR D 1 32  ? -40.602  -18.147 48.134  1.00 73.16  ? 92  THR D CB  1 
ATOM   13188 O OG1 . THR D 1 32  ? -40.593  -19.460 47.559  1.00 72.43  ? 92  THR D OG1 1 
ATOM   13189 C CG2 . THR D 1 32  ? -40.063  -18.130 49.551  1.00 80.91  ? 92  THR D CG2 1 
ATOM   13190 N N   . SER D 1 33  ? -43.773  -19.249 47.500  1.00 50.27  ? 93  SER D N   1 
ATOM   13191 C CA  . SER D 1 33  ? -44.844  -20.248 47.724  1.00 52.94  ? 93  SER D CA  1 
ATOM   13192 C C   . SER D 1 33  ? -44.801  -21.325 46.640  1.00 51.34  ? 93  SER D C   1 
ATOM   13193 O O   . SER D 1 33  ? -44.449  -20.987 45.483  1.00 47.48  ? 93  SER D O   1 
ATOM   13194 C CB  . SER D 1 33  ? -46.161  -19.574 47.721  1.00 57.16  ? 93  SER D CB  1 
ATOM   13195 O OG  . SER D 1 33  ? -46.452  -19.102 46.415  1.00 70.02  ? 93  SER D OG  1 
ATOM   13196 N N   . VAL D 1 34  ? -45.158  -22.560 46.997  1.00 52.67  ? 94  VAL D N   1 
ATOM   13197 C CA  . VAL D 1 34  ? -45.177  -23.707 46.040  1.00 55.43  ? 94  VAL D CA  1 
ATOM   13198 C C   . VAL D 1 34  ? -46.215  -23.369 44.974  1.00 57.80  ? 94  VAL D C   1 
ATOM   13199 O O   . VAL D 1 34  ? -47.319  -23.058 45.374  1.00 69.93  ? 94  VAL D O   1 
ATOM   13200 C CB  . VAL D 1 34  ? -45.551  -25.052 46.683  1.00 56.71  ? 94  VAL D CB  1 
ATOM   13201 C CG1 . VAL D 1 34  ? -45.395  -26.161 45.663  1.00 58.47  ? 94  VAL D CG1 1 
ATOM   13202 C CG2 . VAL D 1 34  ? -44.779  -25.354 47.949  1.00 61.62  ? 94  VAL D CG2 1 
ATOM   13203 N N   . ALA D 1 35  ? -45.869  -23.414 43.689  1.00 58.88  ? 95  ALA D N   1 
ATOM   13204 C CA  . ALA D 1 35  ? -46.798  -23.258 42.546  1.00 55.17  ? 95  ALA D CA  1 
ATOM   13205 C C   . ALA D 1 35  ? -47.545  -24.574 42.252  1.00 54.35  ? 95  ALA D C   1 
ATOM   13206 O O   . ALA D 1 35  ? -46.924  -25.686 42.232  1.00 47.40  ? 95  ALA D O   1 
ATOM   13207 C CB  . ALA D 1 35  ? -46.022  -22.794 41.341  1.00 59.54  ? 95  ALA D CB  1 
ATOM   13208 N N   . SER D 1 36  ? -48.857  -24.452 42.059  1.00 59.28  ? 96  SER D N   1 
ATOM   13209 C CA  . SER D 1 36  ? -49.769  -25.540 41.616  1.00 64.92  ? 96  SER D CA  1 
ATOM   13210 C C   . SER D 1 36  ? -50.969  -24.940 40.860  1.00 62.75  ? 96  SER D C   1 
ATOM   13211 O O   . SER D 1 36  ? -51.049  -23.672 40.754  1.00 57.04  ? 96  SER D O   1 
ATOM   13212 C CB  . SER D 1 36  ? -50.181  -26.412 42.782  1.00 71.24  ? 96  SER D CB  1 
ATOM   13213 O OG  . SER D 1 36  ? -50.361  -25.641 43.952  1.00 93.44  ? 96  SER D OG  1 
ATOM   13214 N N   . GLY D 1 37  ? -51.828  -25.808 40.290  1.00 52.81  ? 97  GLY D N   1 
ATOM   13215 C CA  . GLY D 1 37  ? -52.999  -25.428 39.473  1.00 50.37  ? 97  GLY D CA  1 
ATOM   13216 C C   . GLY D 1 37  ? -52.703  -24.285 38.520  1.00 47.60  ? 97  GLY D C   1 
ATOM   13217 O O   . GLY D 1 37  ? -51.656  -24.295 37.905  1.00 50.63  ? 97  GLY D O   1 
ATOM   13218 N N   . TYR D 1 38  ? -53.603  -23.307 38.409  1.00 53.82  ? 98  TYR D N   1 
ATOM   13219 C CA  . TYR D 1 38  ? -53.526  -22.211 37.403  1.00 55.37  ? 98  TYR D CA  1 
ATOM   13220 C C   . TYR D 1 38  ? -52.328  -21.280 37.671  1.00 56.21  ? 98  TYR D C   1 
ATOM   13221 O O   . TYR D 1 38  ? -51.843  -20.706 36.658  1.00 63.13  ? 98  TYR D O   1 
ATOM   13222 C CB  . TYR D 1 38  ? -54.861  -21.468 37.291  1.00 57.89  ? 98  TYR D CB  1 
ATOM   13223 C CG  . TYR D 1 38  ? -55.819  -22.116 36.320  1.00 54.77  ? 98  TYR D CG  1 
ATOM   13224 C CD1 . TYR D 1 38  ? -55.637  -22.003 34.951  1.00 52.43  ? 98  TYR D CD1 1 
ATOM   13225 C CD2 . TYR D 1 38  ? -56.871  -22.895 36.768  1.00 52.92  ? 98  TYR D CD2 1 
ATOM   13226 C CE1 . TYR D 1 38  ? -56.470  -22.647 34.051  1.00 55.97  ? 98  TYR D CE1 1 
ATOM   13227 C CE2 . TYR D 1 38  ? -57.734  -23.523 35.880  1.00 60.83  ? 98  TYR D CE2 1 
ATOM   13228 C CZ  . TYR D 1 38  ? -57.526  -23.419 34.510  1.00 66.08  ? 98  TYR D CZ  1 
ATOM   13229 O OH  . TYR D 1 38  ? -58.351  -24.054 33.607  1.00 61.83  ? 98  TYR D OH  1 
ATOM   13230 N N   . THR D 1 39  ? -51.827  -21.155 38.911  1.00 51.39  ? 99  THR D N   1 
ATOM   13231 C CA  . THR D 1 39  ? -50.625  -20.330 39.206  1.00 51.20  ? 99  THR D CA  1 
ATOM   13232 C C   . THR D 1 39  ? -49.436  -20.903 38.425  1.00 51.23  ? 99  THR D C   1 
ATOM   13233 O O   . THR D 1 39  ? -48.773  -20.116 37.710  1.00 57.37  ? 99  THR D O   1 
ATOM   13234 C CB  . THR D 1 39  ? -50.266  -20.257 40.693  1.00 58.10  ? 99  THR D CB  1 
ATOM   13235 O OG1 . THR D 1 39  ? -51.438  -20.240 41.510  1.00 62.71  ? 99  THR D OG1 1 
ATOM   13236 C CG2 . THR D 1 39  ? -49.439  -19.027 40.995  1.00 60.40  ? 99  THR D CG2 1 
ATOM   13237 N N   . LEU D 1 40  ? -49.220  -22.225 38.521  1.00 50.46  ? 100 LEU D N   1 
ATOM   13238 C CA  . LEU D 1 40  ? -48.154  -22.982 37.801  1.00 46.24  ? 100 LEU D CA  1 
ATOM   13239 C C   . LEU D 1 40  ? -48.327  -22.842 36.280  1.00 43.70  ? 100 LEU D C   1 
ATOM   13240 O O   . LEU D 1 40  ? -47.327  -22.569 35.604  1.00 52.87  ? 100 LEU D O   1 
ATOM   13241 C CB  . LEU D 1 40  ? -48.207  -24.451 38.240  1.00 46.99  ? 100 LEU D CB  1 
ATOM   13242 C CG  . LEU D 1 40  ? -47.307  -25.438 37.492  1.00 50.39  ? 100 LEU D CG  1 
ATOM   13243 C CD1 . LEU D 1 40  ? -45.857  -24.955 37.476  1.00 53.70  ? 100 LEU D CD1 1 
ATOM   13244 C CD2 . LEU D 1 40  ? -47.391  -26.852 38.090  1.00 49.35  ? 100 LEU D CD2 1 
ATOM   13245 N N   . LEU D 1 41  ? -49.526  -23.056 35.735  1.00 45.80  ? 101 LEU D N   1 
ATOM   13246 C CA  . LEU D 1 41  ? -49.780  -23.047 34.263  1.00 43.50  ? 101 LEU D CA  1 
ATOM   13247 C C   . LEU D 1 41  ? -49.541  -21.642 33.703  1.00 41.04  ? 101 LEU D C   1 
ATOM   13248 O O   . LEU D 1 41  ? -49.007  -21.565 32.602  1.00 45.40  ? 101 LEU D O   1 
ATOM   13249 C CB  . LEU D 1 41  ? -51.220  -23.502 34.004  1.00 47.30  ? 101 LEU D CB  1 
ATOM   13250 C CG  . LEU D 1 41  ? -51.448  -24.940 33.528  1.00 50.89  ? 101 LEU D CG  1 
ATOM   13251 C CD1 . LEU D 1 41  ? -50.716  -25.935 34.390  1.00 56.05  ? 101 LEU D CD1 1 
ATOM   13252 C CD2 . LEU D 1 41  ? -52.933  -25.259 33.477  1.00 52.74  ? 101 LEU D CD2 1 
ATOM   13253 N N   . ARG D 1 42  ? -49.912  -20.589 34.433  1.00 46.18  ? 102 ARG D N   1 
ATOM   13254 C CA  . ARG D 1 42  ? -49.747  -19.174 33.987  1.00 50.81  ? 102 ARG D CA  1 
ATOM   13255 C C   . ARG D 1 42  ? -48.322  -18.651 34.211  1.00 54.57  ? 102 ARG D C   1 
ATOM   13256 O O   . ARG D 1 42  ? -48.056  -17.530 33.718  1.00 53.36  ? 102 ARG D O   1 
ATOM   13257 C CB  . ARG D 1 42  ? -50.793  -18.310 34.679  1.00 59.20  ? 102 ARG D CB  1 
ATOM   13258 C CG  . ARG D 1 42  ? -52.177  -18.550 34.087  1.00 62.44  ? 102 ARG D CG  1 
ATOM   13259 C CD  . ARG D 1 42  ? -53.233  -18.036 35.035  1.00 74.90  ? 102 ARG D CD  1 
ATOM   13260 N NE  . ARG D 1 42  ? -54.540  -17.831 34.422  1.00 74.84  ? 102 ARG D NE  1 
ATOM   13261 C CZ  . ARG D 1 42  ? -55.668  -18.406 34.818  1.00 65.52  ? 102 ARG D CZ  1 
ATOM   13262 N NH1 . ARG D 1 42  ? -55.695  -19.225 35.837  1.00 71.83  ? 102 ARG D NH1 1 
ATOM   13263 N NH2 . ARG D 1 42  ? -56.797  -18.119 34.218  1.00 68.63  ? 102 ARG D NH2 1 
ATOM   13264 N N   . ASP D 1 43  ? -47.458  -19.434 34.881  1.00 54.97  ? 103 ASP D N   1 
ATOM   13265 C CA  . ASP D 1 43  ? -46.006  -19.146 35.106  1.00 57.22  ? 103 ASP D CA  1 
ATOM   13266 C C   . ASP D 1 43  ? -45.165  -19.678 33.939  1.00 55.43  ? 103 ASP D C   1 
ATOM   13267 O O   . ASP D 1 43  ? -44.921  -20.876 33.779  1.00 50.33  ? 103 ASP D O   1 
ATOM   13268 C CB  . ASP D 1 43  ? -45.495  -19.720 36.435  1.00 60.89  ? 103 ASP D CB  1 
ATOM   13269 C CG  . ASP D 1 43  ? -44.036  -19.423 36.765  1.00 59.18  ? 103 ASP D CG  1 
ATOM   13270 O OD1 . ASP D 1 43  ? -43.449  -18.517 36.158  1.00 66.76  ? 103 ASP D OD1 1 
ATOM   13271 O OD2 . ASP D 1 43  ? -43.487  -20.105 37.635  1.00 73.26  ? 103 ASP D OD2 1 
ATOM   13272 N N   . PRO D 1 44  ? -44.628  -18.776 33.102  1.00 55.46  ? 104 PRO D N   1 
ATOM   13273 C CA  . PRO D 1 44  ? -43.842  -19.215 31.960  1.00 54.27  ? 104 PRO D CA  1 
ATOM   13274 C C   . PRO D 1 44  ? -42.618  -20.026 32.381  1.00 56.37  ? 104 PRO D C   1 
ATOM   13275 O O   . PRO D 1 44  ? -42.463  -21.087 31.819  1.00 72.48  ? 104 PRO D O   1 
ATOM   13276 C CB  . PRO D 1 44  ? -43.423  -17.924 31.251  1.00 58.15  ? 104 PRO D CB  1 
ATOM   13277 C CG  . PRO D 1 44  ? -44.277  -16.828 31.868  1.00 52.59  ? 104 PRO D CG  1 
ATOM   13278 C CD  . PRO D 1 44  ? -44.738  -17.313 33.223  1.00 51.21  ? 104 PRO D CD  1 
ATOM   13279 N N   . HIS D 1 45  ? -41.828  -19.546 33.355  1.00 61.69  ? 105 HIS D N   1 
ATOM   13280 C CA  . HIS D 1 45  ? -40.575  -20.203 33.835  1.00 62.79  ? 105 HIS D CA  1 
ATOM   13281 C C   . HIS D 1 45  ? -40.803  -21.716 34.052  1.00 63.35  ? 105 HIS D C   1 
ATOM   13282 O O   . HIS D 1 45  ? -39.923  -22.518 33.656  1.00 63.99  ? 105 HIS D O   1 
ATOM   13283 C CB  . HIS D 1 45  ? -40.013  -19.491 35.079  1.00 71.12  ? 105 HIS D CB  1 
ATOM   13284 C CG  . HIS D 1 45  ? -38.627  -19.934 35.465  1.00 82.86  ? 105 HIS D CG  1 
ATOM   13285 N ND1 . HIS D 1 45  ? -38.350  -21.259 35.834  1.00 72.22  ? 105 HIS D ND1 1 
ATOM   13286 C CD2 . HIS D 1 45  ? -37.447  -19.279 35.549  1.00 91.35  ? 105 HIS D CD2 1 
ATOM   13287 C CE1 . HIS D 1 45  ? -37.073  -21.390 36.129  1.00 71.85  ? 105 HIS D CE1 1 
ATOM   13288 N NE2 . HIS D 1 45  ? -36.501  -20.197 35.948  1.00 88.87  ? 105 HIS D NE2 1 
ATOM   13289 N N   . HIS D 1 46  ? -41.934  -22.128 34.631  1.00 60.73  ? 106 HIS D N   1 
ATOM   13290 C CA  . HIS D 1 46  ? -42.176  -23.550 34.984  1.00 60.36  ? 106 HIS D CA  1 
ATOM   13291 C C   . HIS D 1 46  ? -43.139  -24.226 34.008  1.00 65.31  ? 106 HIS D C   1 
ATOM   13292 O O   . HIS D 1 46  ? -43.025  -25.459 33.857  1.00 69.30  ? 106 HIS D O   1 
ATOM   13293 C CB  . HIS D 1 46  ? -42.662  -23.673 36.426  1.00 65.00  ? 106 HIS D CB  1 
ATOM   13294 C CG  . HIS D 1 46  ? -41.638  -23.213 37.403  1.00 69.86  ? 106 HIS D CG  1 
ATOM   13295 N ND1 . HIS D 1 46  ? -41.832  -22.110 38.215  1.00 68.59  ? 106 HIS D ND1 1 
ATOM   13296 C CD2 . HIS D 1 46  ? -40.393  -23.666 37.661  1.00 67.56  ? 106 HIS D CD2 1 
ATOM   13297 C CE1 . HIS D 1 46  ? -40.750  -21.900 38.922  1.00 69.15  ? 106 HIS D CE1 1 
ATOM   13298 N NE2 . HIS D 1 46  ? -39.859  -22.849 38.612  1.00 73.26  ? 106 HIS D NE2 1 
ATOM   13299 N N   . ASN D 1 47  ? -44.049  -23.477 33.377  1.00 57.25  ? 107 ASN D N   1 
ATOM   13300 C CA  . ASN D 1 47  ? -45.216  -24.108 32.722  1.00 53.65  ? 107 ASN D CA  1 
ATOM   13301 C C   . ASN D 1 47  ? -44.733  -25.078 31.640  1.00 52.74  ? 107 ASN D C   1 
ATOM   13302 O O   . ASN D 1 47  ? -44.106  -24.623 30.693  1.00 59.75  ? 107 ASN D O   1 
ATOM   13303 C CB  . ASN D 1 47  ? -46.196  -23.098 32.132  1.00 50.98  ? 107 ASN D CB  1 
ATOM   13304 C CG  . ASN D 1 47  ? -47.110  -23.762 31.133  1.00 46.17  ? 107 ASN D CG  1 
ATOM   13305 O OD1 . ASN D 1 47  ? -47.843  -24.686 31.486  1.00 46.71  ? 107 ASN D OD1 1 
ATOM   13306 N ND2 . ASN D 1 47  ? -46.987  -23.368 29.884  1.00 38.15  ? 107 ASN D ND2 1 
ATOM   13307 N N   . LYS D 1 48  ? -45.098  -26.353 31.746  1.00 51.09  ? 108 LYS D N   1 
ATOM   13308 C CA  . LYS D 1 48  ? -44.779  -27.400 30.748  1.00 45.45  ? 108 LYS D CA  1 
ATOM   13309 C C   . LYS D 1 48  ? -45.992  -27.716 29.870  1.00 43.26  ? 108 LYS D C   1 
ATOM   13310 O O   . LYS D 1 48  ? -45.836  -28.627 29.055  1.00 49.37  ? 108 LYS D O   1 
ATOM   13311 C CB  . LYS D 1 48  ? -44.286  -28.677 31.435  1.00 44.17  ? 108 LYS D CB  1 
ATOM   13312 C CG  . LYS D 1 48  ? -43.044  -28.498 32.301  1.00 46.70  ? 108 LYS D CG  1 
ATOM   13313 C CD  . LYS D 1 48  ? -42.600  -29.733 33.053  1.00 49.59  ? 108 LYS D CD  1 
ATOM   13314 C CE  . LYS D 1 48  ? -42.507  -30.979 32.191  1.00 60.99  ? 108 LYS D CE  1 
ATOM   13315 N NZ  . LYS D 1 48  ? -42.146  -32.197 32.969  1.00 59.44  ? 108 LYS D NZ  1 
ATOM   13316 N N   . GLY D 1 49  ? -47.138  -27.033 29.999  1.00 37.86  ? 109 GLY D N   1 
ATOM   13317 C CA  . GLY D 1 49  ? -48.358  -27.417 29.244  1.00 39.88  ? 109 GLY D CA  1 
ATOM   13318 C C   . GLY D 1 49  ? -48.567  -28.931 29.263  1.00 39.85  ? 109 GLY D C   1 
ATOM   13319 O O   . GLY D 1 49  ? -48.238  -29.552 30.294  1.00 37.86  ? 109 GLY D O   1 
ATOM   13320 N N   . LEU D 1 50  ? -48.986  -29.545 28.156  1.00 38.52  ? 110 LEU D N   1 
ATOM   13321 C CA  . LEU D 1 50  ? -49.348  -30.996 28.122  1.00 45.41  ? 110 LEU D CA  1 
ATOM   13322 C C   . LEU D 1 50  ? -48.151  -31.913 28.429  1.00 48.99  ? 110 LEU D C   1 
ATOM   13323 O O   . LEU D 1 50  ? -48.374  -33.137 28.463  1.00 45.09  ? 110 LEU D O   1 
ATOM   13324 C CB  . LEU D 1 50  ? -49.898  -31.388 26.755  1.00 46.98  ? 110 LEU D CB  1 
ATOM   13325 C CG  . LEU D 1 50  ? -51.107  -30.593 26.291  1.00 48.12  ? 110 LEU D CG  1 
ATOM   13326 C CD1 . LEU D 1 50  ? -51.503  -30.962 24.867  1.00 51.71  ? 110 LEU D CD1 1 
ATOM   13327 C CD2 . LEU D 1 50  ? -52.239  -30.853 27.246  1.00 56.89  ? 110 LEU D CD2 1 
ATOM   13328 N N   . ALA D 1 51  ? -46.945  -31.367 28.599  1.00 52.38  ? 111 ALA D N   1 
ATOM   13329 C CA  . ALA D 1 51  ? -45.708  -32.143 28.839  1.00 54.94  ? 111 ALA D CA  1 
ATOM   13330 C C   . ALA D 1 51  ? -45.604  -32.471 30.326  1.00 57.99  ? 111 ALA D C   1 
ATOM   13331 O O   . ALA D 1 51  ? -44.818  -33.381 30.661  1.00 61.53  ? 111 ALA D O   1 
ATOM   13332 C CB  . ALA D 1 51  ? -44.479  -31.428 28.320  1.00 57.18  ? 111 ALA D CB  1 
ATOM   13333 N N   . PHE D 1 52  ? -46.395  -31.801 31.174  1.00 60.59  ? 112 PHE D N   1 
ATOM   13334 C CA  . PHE D 1 52  ? -46.613  -32.208 32.599  1.00 51.46  ? 112 PHE D CA  1 
ATOM   13335 C C   . PHE D 1 52  ? -47.006  -33.688 32.675  1.00 49.72  ? 112 PHE D C   1 
ATOM   13336 O O   . PHE D 1 52  ? -48.052  -34.078 32.111  1.00 56.04  ? 112 PHE D O   1 
ATOM   13337 C CB  . PHE D 1 52  ? -47.694  -31.365 33.270  1.00 43.11  ? 112 PHE D CB  1 
ATOM   13338 C CG  . PHE D 1 52  ? -47.167  -30.075 33.812  1.00 43.82  ? 112 PHE D CG  1 
ATOM   13339 C CD1 . PHE D 1 52  ? -46.166  -30.088 34.761  1.00 52.88  ? 112 PHE D CD1 1 
ATOM   13340 C CD2 . PHE D 1 52  ? -47.651  -28.855 33.382  1.00 46.75  ? 112 PHE D CD2 1 
ATOM   13341 C CE1 . PHE D 1 52  ? -45.647  -28.904 35.271  1.00 57.24  ? 112 PHE D CE1 1 
ATOM   13342 C CE2 . PHE D 1 52  ? -47.143  -27.671 33.898  1.00 46.95  ? 112 PHE D CE2 1 
ATOM   13343 C CZ  . PHE D 1 52  ? -46.133  -27.695 34.833  1.00 50.44  ? 112 PHE D CZ  1 
ATOM   13344 N N   . THR D 1 53  ? -46.173  -34.499 33.315  1.00 48.84  ? 113 THR D N   1 
ATOM   13345 C CA  . THR D 1 53  ? -46.389  -35.955 33.471  1.00 53.46  ? 113 THR D CA  1 
ATOM   13346 C C   . THR D 1 53  ? -47.635  -36.179 34.335  1.00 64.43  ? 113 THR D C   1 
ATOM   13347 O O   . THR D 1 53  ? -47.976  -35.261 35.111  1.00 71.12  ? 113 THR D O   1 
ATOM   13348 C CB  . THR D 1 53  ? -45.149  -36.644 34.061  1.00 52.99  ? 113 THR D CB  1 
ATOM   13349 O OG1 . THR D 1 53  ? -44.904  -36.202 35.398  1.00 42.54  ? 113 THR D OG1 1 
ATOM   13350 C CG2 . THR D 1 53  ? -43.910  -36.413 33.225  1.00 57.98  ? 113 THR D CG2 1 
ATOM   13351 N N   . GLU D 1 54  ? -48.270  -37.351 34.204  1.00 69.92  ? 114 GLU D N   1 
ATOM   13352 C CA  . GLU D 1 54  ? -49.463  -37.760 35.004  1.00 67.72  ? 114 GLU D CA  1 
ATOM   13353 C C   . GLU D 1 54  ? -49.197  -37.453 36.489  1.00 66.57  ? 114 GLU D C   1 
ATOM   13354 O O   . GLU D 1 54  ? -50.025  -36.755 37.106  1.00 58.72  ? 114 GLU D O   1 
ATOM   13355 C CB  . GLU D 1 54  ? -49.754  -39.245 34.757  1.00 72.36  ? 114 GLU D CB  1 
ATOM   13356 C CG  . GLU D 1 54  ? -51.209  -39.628 34.963  1.00 76.83  ? 114 GLU D CG  1 
ATOM   13357 C CD  . GLU D 1 54  ? -51.702  -40.768 34.084  1.00 88.37  ? 114 GLU D CD  1 
ATOM   13358 O OE1 . GLU D 1 54  ? -51.814  -41.907 34.602  1.00 101.32 ? 114 GLU D OE1 1 
ATOM   13359 O OE2 . GLU D 1 54  ? -51.989  -40.512 32.885  1.00 84.59  ? 114 GLU D OE2 1 
ATOM   13360 N N   . GLU D 1 55  ? -48.041  -37.908 37.001  1.00 64.06  ? 115 GLU D N   1 
ATOM   13361 C CA  . GLU D 1 55  ? -47.594  -37.813 38.415  1.00 58.77  ? 115 GLU D CA  1 
ATOM   13362 C C   . GLU D 1 55  ? -47.504  -36.338 38.804  1.00 54.65  ? 115 GLU D C   1 
ATOM   13363 O O   . GLU D 1 55  ? -47.945  -36.010 39.904  1.00 53.76  ? 115 GLU D O   1 
ATOM   13364 C CB  . GLU D 1 55  ? -46.240  -38.514 38.601  1.00 69.32  ? 115 GLU D CB  1 
ATOM   13365 C CG  . GLU D 1 55  ? -46.223  -39.980 38.163  1.00 95.38  ? 115 GLU D CG  1 
ATOM   13366 C CD  . GLU D 1 55  ? -45.829  -40.364 36.721  1.00 117.15 ? 115 GLU D CD  1 
ATOM   13367 O OE1 . GLU D 1 55  ? -45.211  -39.540 35.949  1.00 102.57 ? 115 GLU D OE1 1 
ATOM   13368 O OE2 . GLU D 1 55  ? -46.186  -41.497 36.341  1.00 139.13 ? 115 GLU D OE2 1 
ATOM   13369 N N   . GLU D 1 56  ? -46.989  -35.475 37.924  1.00 52.36  ? 116 GLU D N   1 
ATOM   13370 C CA  . GLU D 1 56  ? -46.836  -34.016 38.184  1.00 57.81  ? 116 GLU D CA  1 
ATOM   13371 C C   . GLU D 1 56  ? -48.199  -33.338 38.298  1.00 59.22  ? 116 GLU D C   1 
ATOM   13372 O O   . GLU D 1 56  ? -48.284  -32.394 39.099  1.00 64.23  ? 116 GLU D O   1 
ATOM   13373 C CB  . GLU D 1 56  ? -46.053  -33.328 37.067  1.00 61.28  ? 116 GLU D CB  1 
ATOM   13374 C CG  . GLU D 1 56  ? -44.582  -33.688 37.068  1.00 69.72  ? 116 GLU D CG  1 
ATOM   13375 C CD  . GLU D 1 56  ? -43.758  -33.196 35.888  1.00 67.27  ? 116 GLU D CD  1 
ATOM   13376 O OE1 . GLU D 1 56  ? -44.330  -32.962 34.831  1.00 73.81  ? 116 GLU D OE1 1 
ATOM   13377 O OE2 . GLU D 1 56  ? -42.545  -33.050 36.024  1.00 76.33  ? 116 GLU D OE2 1 
ATOM   13378 N N   . ARG D 1 57  ? -49.185  -33.792 37.507  1.00 53.91  ? 117 ARG D N   1 
ATOM   13379 C CA  . ARG D 1 57  ? -50.563  -33.234 37.456  1.00 53.08  ? 117 ARG D CA  1 
ATOM   13380 C C   . ARG D 1 57  ? -51.322  -33.555 38.765  1.00 59.72  ? 117 ARG D C   1 
ATOM   13381 O O   . ARG D 1 57  ? -51.924  -32.614 39.365  1.00 58.95  ? 117 ARG D O   1 
ATOM   13382 C CB  . ARG D 1 57  ? -51.314  -33.780 36.244  1.00 53.56  ? 117 ARG D CB  1 
ATOM   13383 C CG  . ARG D 1 57  ? -50.643  -33.540 34.899  1.00 58.41  ? 117 ARG D CG  1 
ATOM   13384 C CD  . ARG D 1 57  ? -51.539  -33.770 33.679  1.00 58.91  ? 117 ARG D CD  1 
ATOM   13385 N NE  . ARG D 1 57  ? -50.847  -33.594 32.407  1.00 60.08  ? 117 ARG D NE  1 
ATOM   13386 C CZ  . ARG D 1 57  ? -51.386  -33.782 31.207  1.00 60.67  ? 117 ARG D CZ  1 
ATOM   13387 N NH1 . ARG D 1 57  ? -52.651  -34.147 31.089  1.00 64.02  ? 117 ARG D NH1 1 
ATOM   13388 N NH2 . ARG D 1 57  ? -50.656  -33.621 30.118  1.00 58.10  ? 117 ARG D NH2 1 
ATOM   13389 N N   . ASP D 1 58  ? -51.322  -34.825 39.191  1.00 59.30  ? 118 ASP D N   1 
ATOM   13390 C CA  . ASP D 1 58  ? -51.889  -35.268 40.500  1.00 59.00  ? 118 ASP D CA  1 
ATOM   13391 C C   . ASP D 1 58  ? -51.239  -34.437 41.613  1.00 56.94  ? 118 ASP D C   1 
ATOM   13392 O O   . ASP D 1 58  ? -51.945  -33.845 42.439  1.00 57.16  ? 118 ASP D O   1 
ATOM   13393 C CB  . ASP D 1 58  ? -51.679  -36.764 40.726  1.00 60.17  ? 118 ASP D CB  1 
ATOM   13394 C CG  . ASP D 1 58  ? -52.436  -37.629 39.714  1.00 68.58  ? 118 ASP D CG  1 
ATOM   13395 O OD1 . ASP D 1 58  ? -53.205  -37.070 38.885  1.00 61.60  ? 118 ASP D OD1 1 
ATOM   13396 O OD2 . ASP D 1 58  ? -52.247  -38.867 39.735  1.00 80.18  ? 118 ASP D OD2 1 
ATOM   13397 N N   . GLY D 1 59  ? -49.917  -34.363 41.569  1.00 55.39  ? 119 GLY D N   1 
ATOM   13398 C CA  . GLY D 1 59  ? -49.082  -33.664 42.554  1.00 55.70  ? 119 GLY D CA  1 
ATOM   13399 C C   . GLY D 1 59  ? -49.432  -32.192 42.671  1.00 52.97  ? 119 GLY D C   1 
ATOM   13400 O O   . GLY D 1 59  ? -49.326  -31.685 43.781  1.00 61.19  ? 119 GLY D O   1 
ATOM   13401 N N   . HIS D 1 60  ? -49.801  -31.507 41.590  1.00 44.13  ? 120 HIS D N   1 
ATOM   13402 C CA  . HIS D 1 60  ? -49.865  -30.025 41.587  1.00 49.56  ? 120 HIS D CA  1 
ATOM   13403 C C   . HIS D 1 60  ? -51.237  -29.533 41.165  1.00 55.21  ? 120 HIS D C   1 
ATOM   13404 O O   . HIS D 1 60  ? -51.317  -28.360 40.735  1.00 57.12  ? 120 HIS D O   1 
ATOM   13405 C CB  . HIS D 1 60  ? -48.770  -29.396 40.714  1.00 57.84  ? 120 HIS D CB  1 
ATOM   13406 C CG  . HIS D 1 60  ? -47.396  -29.622 41.246  1.00 67.75  ? 120 HIS D CG  1 
ATOM   13407 N ND1 . HIS D 1 60  ? -46.660  -30.728 40.844  1.00 69.59  ? 120 HIS D ND1 1 
ATOM   13408 C CD2 . HIS D 1 60  ? -46.640  -28.951 42.147  1.00 62.19  ? 120 HIS D CD2 1 
ATOM   13409 C CE1 . HIS D 1 60  ? -45.498  -30.718 41.446  1.00 68.47  ? 120 HIS D CE1 1 
ATOM   13410 N NE2 . HIS D 1 60  ? -45.465  -29.643 42.262  1.00 69.16  ? 120 HIS D NE2 1 
ATOM   13411 N N   . TYR D 1 61  ? -52.267  -30.366 41.316  1.00 61.94  ? 121 TYR D N   1 
ATOM   13412 C CA  . TYR D 1 61  ? -53.679  -29.947 41.133  1.00 66.99  ? 121 TYR D CA  1 
ATOM   13413 C C   . TYR D 1 61  ? -53.865  -29.407 39.712  1.00 61.85  ? 121 TYR D C   1 
ATOM   13414 O O   . TYR D 1 61  ? -54.456  -28.320 39.522  1.00 62.91  ? 121 TYR D O   1 
ATOM   13415 C CB  . TYR D 1 61  ? -54.041  -28.937 42.223  1.00 66.06  ? 121 TYR D CB  1 
ATOM   13416 C CG  . TYR D 1 61  ? -53.675  -29.414 43.604  1.00 68.37  ? 121 TYR D CG  1 
ATOM   13417 C CD1 . TYR D 1 61  ? -54.237  -30.576 44.116  1.00 72.04  ? 121 TYR D CD1 1 
ATOM   13418 C CD2 . TYR D 1 61  ? -52.745  -28.736 44.382  1.00 66.13  ? 121 TYR D CD2 1 
ATOM   13419 C CE1 . TYR D 1 61  ? -53.902  -31.044 45.374  1.00 71.84  ? 121 TYR D CE1 1 
ATOM   13420 C CE2 . TYR D 1 61  ? -52.425  -29.175 45.655  1.00 61.57  ? 121 TYR D CE2 1 
ATOM   13421 C CZ  . TYR D 1 61  ? -53.015  -30.326 46.151  1.00 69.32  ? 121 TYR D CZ  1 
ATOM   13422 O OH  . TYR D 1 61  ? -52.719  -30.819 47.386  1.00 93.61  ? 121 TYR D OH  1 
ATOM   13423 N N   . LEU D 1 62  ? -53.347  -30.160 38.746  1.00 54.83  ? 122 LEU D N   1 
ATOM   13424 C CA  . LEU D 1 62  ? -53.561  -29.910 37.300  1.00 56.29  ? 122 LEU D CA  1 
ATOM   13425 C C   . LEU D 1 62  ? -54.636  -30.856 36.762  1.00 58.78  ? 122 LEU D C   1 
ATOM   13426 O O   . LEU D 1 62  ? -55.335  -30.445 35.821  1.00 53.71  ? 122 LEU D O   1 
ATOM   13427 C CB  . LEU D 1 62  ? -52.252  -30.116 36.552  1.00 50.22  ? 122 LEU D CB  1 
ATOM   13428 C CG  . LEU D 1 62  ? -51.096  -29.243 37.024  1.00 51.88  ? 122 LEU D CG  1 
ATOM   13429 C CD1 . LEU D 1 62  ? -49.855  -29.444 36.152  1.00 52.99  ? 122 LEU D CD1 1 
ATOM   13430 C CD2 . LEU D 1 62  ? -51.498  -27.780 37.044  1.00 47.86  ? 122 LEU D CD2 1 
ATOM   13431 N N   . ARG D 1 63  ? -54.776  -32.058 37.352  1.00 59.22  ? 123 ARG D N   1 
ATOM   13432 C CA  . ARG D 1 63  ? -55.723  -33.087 36.859  1.00 51.65  ? 123 ARG D CA  1 
ATOM   13433 C C   . ARG D 1 63  ? -57.046  -32.373 36.556  1.00 50.89  ? 123 ARG D C   1 
ATOM   13434 O O   . ARG D 1 63  ? -57.561  -31.678 37.450  1.00 47.37  ? 123 ARG D O   1 
ATOM   13435 C CB  . ARG D 1 63  ? -55.862  -34.227 37.863  1.00 48.18  ? 123 ARG D CB  1 
ATOM   13436 C CG  . ARG D 1 63  ? -56.614  -35.427 37.313  1.00 52.15  ? 123 ARG D CG  1 
ATOM   13437 C CD  . ARG D 1 63  ? -57.023  -36.331 38.450  1.00 69.26  ? 123 ARG D CD  1 
ATOM   13438 N NE  . ARG D 1 63  ? -56.184  -37.523 38.552  1.00 84.15  ? 123 ARG D NE  1 
ATOM   13439 C CZ  . ARG D 1 63  ? -56.621  -38.782 38.615  1.00 92.43  ? 123 ARG D CZ  1 
ATOM   13440 N NH1 . ARG D 1 63  ? -57.913  -39.059 38.620  1.00 105.51 ? 123 ARG D NH1 1 
ATOM   13441 N NH2 . ARG D 1 63  ? -55.769  -39.785 38.714  1.00 100.71 ? 123 ARG D NH2 1 
ATOM   13442 N N   . GLY D 1 64  ? -57.528  -32.468 35.317  1.00 46.27  ? 124 GLY D N   1 
ATOM   13443 C CA  . GLY D 1 64  ? -58.774  -31.821 34.876  1.00 44.10  ? 124 GLY D CA  1 
ATOM   13444 C C   . GLY D 1 64  ? -58.515  -30.548 34.091  1.00 48.62  ? 124 GLY D C   1 
ATOM   13445 O O   . GLY D 1 64  ? -59.210  -30.335 33.076  1.00 46.83  ? 124 GLY D O   1 
ATOM   13446 N N   . LEU D 1 65  ? -57.567  -29.711 34.529  1.00 56.01  ? 125 LEU D N   1 
ATOM   13447 C CA  . LEU D 1 65  ? -57.241  -28.415 33.859  1.00 51.59  ? 125 LEU D CA  1 
ATOM   13448 C C   . LEU D 1 65  ? -56.515  -28.692 32.537  1.00 46.92  ? 125 LEU D C   1 
ATOM   13449 O O   . LEU D 1 65  ? -56.476  -27.788 31.712  1.00 52.60  ? 125 LEU D O   1 
ATOM   13450 C CB  . LEU D 1 65  ? -56.335  -27.572 34.758  1.00 51.84  ? 125 LEU D CB  1 
ATOM   13451 C CG  . LEU D 1 65  ? -56.937  -27.071 36.052  1.00 49.69  ? 125 LEU D CG  1 
ATOM   13452 C CD1 . LEU D 1 65  ? -57.319  -28.202 36.962  1.00 59.13  ? 125 LEU D CD1 1 
ATOM   13453 C CD2 . LEU D 1 65  ? -55.955  -26.150 36.742  1.00 50.27  ? 125 LEU D CD2 1 
ATOM   13454 N N   . LEU D 1 66  ? -55.889  -29.863 32.394  1.00 43.20  ? 126 LEU D N   1 
ATOM   13455 C CA  . LEU D 1 66  ? -55.306  -30.355 31.119  1.00 46.94  ? 126 LEU D CA  1 
ATOM   13456 C C   . LEU D 1 66  ? -56.113  -31.538 30.615  1.00 43.94  ? 126 LEU D C   1 
ATOM   13457 O O   . LEU D 1 66  ? -56.631  -32.328 31.398  1.00 48.76  ? 126 LEU D O   1 
ATOM   13458 C CB  . LEU D 1 66  ? -53.847  -30.768 31.328  1.00 50.04  ? 126 LEU D CB  1 
ATOM   13459 C CG  . LEU D 1 66  ? -52.923  -29.680 31.862  1.00 51.86  ? 126 LEU D CG  1 
ATOM   13460 C CD1 . LEU D 1 66  ? -51.520  -30.234 32.021  1.00 50.24  ? 126 LEU D CD1 1 
ATOM   13461 C CD2 . LEU D 1 66  ? -52.941  -28.439 30.966  1.00 54.10  ? 126 LEU D CD2 1 
ATOM   13462 N N   . PRO D 1 67  ? -56.190  -31.716 29.289  1.00 46.87  ? 127 PRO D N   1 
ATOM   13463 C CA  . PRO D 1 67  ? -56.742  -32.946 28.723  1.00 54.45  ? 127 PRO D CA  1 
ATOM   13464 C C   . PRO D 1 67  ? -55.942  -34.166 29.181  1.00 50.06  ? 127 PRO D C   1 
ATOM   13465 O O   . PRO D 1 67  ? -54.815  -34.011 29.619  1.00 43.93  ? 127 PRO D O   1 
ATOM   13466 C CB  . PRO D 1 67  ? -56.549  -32.795 27.209  1.00 55.57  ? 127 PRO D CB  1 
ATOM   13467 C CG  . PRO D 1 67  ? -56.163  -31.350 26.985  1.00 51.77  ? 127 PRO D CG  1 
ATOM   13468 C CD  . PRO D 1 67  ? -55.670  -30.778 28.288  1.00 46.24  ? 127 PRO D CD  1 
ATOM   13469 N N   . PRO D 1 68  ? -56.458  -35.404 29.068  1.00 54.30  ? 128 PRO D N   1 
ATOM   13470 C CA  . PRO D 1 68  ? -55.734  -36.601 29.517  1.00 56.21  ? 128 PRO D CA  1 
ATOM   13471 C C   . PRO D 1 68  ? -54.338  -36.849 28.907  1.00 53.10  ? 128 PRO D C   1 
ATOM   13472 O O   . PRO D 1 68  ? -53.481  -37.359 29.609  1.00 51.31  ? 128 PRO D O   1 
ATOM   13473 C CB  . PRO D 1 68  ? -56.621  -37.795 29.132  1.00 58.98  ? 128 PRO D CB  1 
ATOM   13474 C CG  . PRO D 1 68  ? -57.976  -37.197 28.726  1.00 70.89  ? 128 PRO D CG  1 
ATOM   13475 C CD  . PRO D 1 68  ? -57.779  -35.703 28.503  1.00 66.55  ? 128 PRO D CD  1 
ATOM   13476 N N   . ALA D 1 69  ? -54.136  -36.467 27.643  1.00 54.56  ? 129 ALA D N   1 
ATOM   13477 C CA  . ALA D 1 69  ? -52.918  -36.726 26.837  1.00 62.27  ? 129 ALA D CA  1 
ATOM   13478 C C   . ALA D 1 69  ? -51.692  -36.011 27.437  1.00 65.52  ? 129 ALA D C   1 
ATOM   13479 O O   . ALA D 1 69  ? -51.739  -34.751 27.629  1.00 65.03  ? 129 ALA D O   1 
ATOM   13480 C CB  . ALA D 1 69  ? -53.129  -36.307 25.393  1.00 54.40  ? 129 ALA D CB  1 
ATOM   13481 N N   . VAL D 1 70  ? -50.609  -36.784 27.607  1.00 55.56  ? 130 VAL D N   1 
ATOM   13482 C CA  . VAL D 1 70  ? -49.255  -36.279 27.953  1.00 52.37  ? 130 VAL D CA  1 
ATOM   13483 C C   . VAL D 1 70  ? -48.379  -36.306 26.697  1.00 50.37  ? 130 VAL D C   1 
ATOM   13484 O O   . VAL D 1 70  ? -48.084  -37.407 26.183  1.00 43.06  ? 130 VAL D O   1 
ATOM   13485 C CB  . VAL D 1 70  ? -48.631  -37.076 29.116  1.00 49.55  ? 130 VAL D CB  1 
ATOM   13486 C CG1 . VAL D 1 70  ? -47.264  -36.525 29.498  1.00 46.94  ? 130 VAL D CG1 1 
ATOM   13487 C CG2 . VAL D 1 70  ? -49.549  -37.085 30.328  1.00 50.00  ? 130 VAL D CG2 1 
ATOM   13488 N N   . LEU D 1 71  ? -47.961  -35.117 26.245  1.00 53.26  ? 131 LEU D N   1 
ATOM   13489 C CA  . LEU D 1 71  ? -46.963  -34.929 25.159  1.00 53.85  ? 131 LEU D CA  1 
ATOM   13490 C C   . LEU D 1 71  ? -45.544  -34.892 25.741  1.00 58.91  ? 131 LEU D C   1 
ATOM   13491 O O   . LEU D 1 71  ? -45.358  -34.416 26.885  1.00 64.16  ? 131 LEU D O   1 
ATOM   13492 C CB  . LEU D 1 71  ? -47.248  -33.607 24.459  1.00 53.92  ? 131 LEU D CB  1 
ATOM   13493 C CG  . LEU D 1 71  ? -48.372  -33.672 23.439  1.00 53.24  ? 131 LEU D CG  1 
ATOM   13494 C CD1 . LEU D 1 71  ? -48.618  -32.298 22.812  1.00 50.52  ? 131 LEU D CD1 1 
ATOM   13495 C CD2 . LEU D 1 71  ? -48.034  -34.742 22.407  1.00 57.64  ? 131 LEU D CD2 1 
ATOM   13496 N N   . SER D 1 72  ? -44.574  -35.342 24.947  1.00 53.62  ? 132 SER D N   1 
ATOM   13497 C CA  . SER D 1 72  ? -43.136  -35.024 25.122  1.00 52.64  ? 132 SER D CA  1 
ATOM   13498 C C   . SER D 1 72  ? -42.850  -33.566 24.707  1.00 57.47  ? 132 SER D C   1 
ATOM   13499 O O   . SER D 1 72  ? -43.699  -32.924 24.028  1.00 46.36  ? 132 SER D O   1 
ATOM   13500 C CB  . SER D 1 72  ? -42.303  -35.965 24.332  1.00 52.61  ? 132 SER D CB  1 
ATOM   13501 O OG  . SER D 1 72  ? -42.451  -35.697 22.940  1.00 52.78  ? 132 SER D OG  1 
ATOM   13502 N N   . GLN D 1 73  ? -41.666  -33.065 25.071  1.00 62.01  ? 133 GLN D N   1 
ATOM   13503 C CA  . GLN D 1 73  ? -41.192  -31.737 24.622  1.00 59.59  ? 133 GLN D CA  1 
ATOM   13504 C C   . GLN D 1 73  ? -41.010  -31.784 23.103  1.00 62.03  ? 133 GLN D C   1 
ATOM   13505 O O   . GLN D 1 73  ? -41.241  -30.760 22.465  1.00 59.81  ? 133 GLN D O   1 
ATOM   13506 C CB  . GLN D 1 73  ? -39.908  -31.353 25.367  1.00 56.56  ? 133 GLN D CB  1 
ATOM   13507 C CG  . GLN D 1 73  ? -39.586  -29.866 25.267  1.00 53.37  ? 133 GLN D CG  1 
ATOM   13508 C CD  . GLN D 1 73  ? -38.396  -29.457 26.086  1.00 54.38  ? 133 GLN D CD  1 
ATOM   13509 O OE1 . GLN D 1 73  ? -37.671  -30.305 26.608  1.00 54.58  ? 133 GLN D OE1 1 
ATOM   13510 N NE2 . GLN D 1 73  ? -38.203  -28.145 26.196  1.00 58.01  ? 133 GLN D NE2 1 
ATOM   13511 N N   . GLU D 1 74  ? -40.610  -32.938 22.549  1.00 82.23  ? 134 GLU D N   1 
ATOM   13512 C CA  . GLU D 1 74  ? -40.245  -33.124 21.112  1.00 79.52  ? 134 GLU D CA  1 
ATOM   13513 C C   . GLU D 1 74  ? -41.502  -33.004 20.258  1.00 76.51  ? 134 GLU D C   1 
ATOM   13514 O O   . GLU D 1 74  ? -41.459  -32.297 19.223  1.00 70.03  ? 134 GLU D O   1 
ATOM   13515 C CB  . GLU D 1 74  ? -39.574  -34.487 20.883  1.00 87.30  ? 134 GLU D CB  1 
ATOM   13516 C CG  . GLU D 1 74  ? -38.076  -34.451 21.111  1.00 97.71  ? 134 GLU D CG  1 
ATOM   13517 C CD  . GLU D 1 74  ? -37.411  -33.360 20.283  1.00 102.85 ? 134 GLU D CD  1 
ATOM   13518 O OE1 . GLU D 1 74  ? -36.357  -32.881 20.703  1.00 84.09  ? 134 GLU D OE1 1 
ATOM   13519 O OE2 . GLU D 1 74  ? -37.985  -32.964 19.231  1.00 119.86 ? 134 GLU D OE2 1 
ATOM   13520 N N   . LEU D 1 75  ? -42.556  -33.707 20.678  1.00 68.66  ? 135 LEU D N   1 
ATOM   13521 C CA  . LEU D 1 75  ? -43.891  -33.630 20.049  1.00 59.32  ? 135 LEU D CA  1 
ATOM   13522 C C   . LEU D 1 75  ? -44.357  -32.177 20.130  1.00 52.41  ? 135 LEU D C   1 
ATOM   13523 O O   . LEU D 1 75  ? -44.877  -31.678 19.143  1.00 53.20  ? 135 LEU D O   1 
ATOM   13524 C CB  . LEU D 1 75  ? -44.846  -34.568 20.786  1.00 67.02  ? 135 LEU D CB  1 
ATOM   13525 C CG  . LEU D 1 75  ? -45.055  -35.966 20.207  1.00 66.60  ? 135 LEU D CG  1 
ATOM   13526 C CD1 . LEU D 1 75  ? -45.941  -35.863 18.995  1.00 71.42  ? 135 LEU D CD1 1 
ATOM   13527 C CD2 . LEU D 1 75  ? -43.747  -36.667 19.873  1.00 66.40  ? 135 LEU D CD2 1 
ATOM   13528 N N   . GLN D 1 76  ? -44.165  -31.513 21.270  1.00 58.25  ? 136 GLN D N   1 
ATOM   13529 C CA  . GLN D 1 76  ? -44.529  -30.072 21.453  1.00 62.68  ? 136 GLN D CA  1 
ATOM   13530 C C   . GLN D 1 76  ? -43.859  -29.239 20.348  1.00 61.93  ? 136 GLN D C   1 
ATOM   13531 O O   . GLN D 1 76  ? -44.559  -28.393 19.742  1.00 64.90  ? 136 GLN D O   1 
ATOM   13532 C CB  . GLN D 1 76  ? -44.134  -29.540 22.840  1.00 63.27  ? 136 GLN D CB  1 
ATOM   13533 C CG  . GLN D 1 76  ? -45.186  -29.744 23.920  1.00 64.82  ? 136 GLN D CG  1 
ATOM   13534 C CD  . GLN D 1 76  ? -44.705  -29.363 25.304  1.00 65.73  ? 136 GLN D CD  1 
ATOM   13535 O OE1 . GLN D 1 76  ? -43.512  -29.242 25.566  1.00 70.99  ? 136 GLN D OE1 1 
ATOM   13536 N NE2 . GLN D 1 76  ? -45.642  -29.180 26.218  1.00 60.49  ? 136 GLN D NE2 1 
ATOM   13537 N N   . ILE D 1 77  ? -42.562  -29.464 20.104  1.00 59.06  ? 137 ILE D N   1 
ATOM   13538 C CA  . ILE D 1 77  ? -41.731  -28.700 19.121  1.00 59.16  ? 137 ILE D CA  1 
ATOM   13539 C C   . ILE D 1 77  ? -42.362  -28.916 17.738  1.00 57.99  ? 137 ILE D C   1 
ATOM   13540 O O   . ILE D 1 77  ? -42.652  -27.906 17.048  1.00 57.92  ? 137 ILE D O   1 
ATOM   13541 C CB  . ILE D 1 77  ? -40.245  -29.142 19.150  1.00 59.36  ? 137 ILE D CB  1 
ATOM   13542 C CG1 . ILE D 1 77  ? -39.547  -28.972 20.495  1.00 52.85  ? 137 ILE D CG1 1 
ATOM   13543 C CG2 . ILE D 1 77  ? -39.456  -28.453 18.051  1.00 69.02  ? 137 ILE D CG2 1 
ATOM   13544 C CD1 . ILE D 1 77  ? -39.340  -27.569 20.906  1.00 50.95  ? 137 ILE D CD1 1 
ATOM   13545 N N   . LYS D 1 78  ? -42.595  -30.185 17.371  1.00 53.26  ? 138 LYS D N   1 
ATOM   13546 C CA  . LYS D 1 78  ? -43.171  -30.585 16.064  1.00 52.88  ? 138 LYS D CA  1 
ATOM   13547 C C   . LYS D 1 78  ? -44.502  -29.835 15.864  1.00 49.97  ? 138 LYS D C   1 
ATOM   13548 O O   . LYS D 1 78  ? -44.699  -29.274 14.768  1.00 46.12  ? 138 LYS D O   1 
ATOM   13549 C CB  . LYS D 1 78  ? -43.337  -32.112 15.991  1.00 52.54  ? 138 LYS D CB  1 
ATOM   13550 C CG  . LYS D 1 78  ? -43.740  -32.607 14.615  1.00 55.59  ? 138 LYS D CG  1 
ATOM   13551 C CD  . LYS D 1 78  ? -44.580  -33.857 14.598  1.00 62.40  ? 138 LYS D CD  1 
ATOM   13552 C CE  . LYS D 1 78  ? -44.852  -34.356 13.189  1.00 64.78  ? 138 LYS D CE  1 
ATOM   13553 N NZ  . LYS D 1 78  ? -44.205  -35.667 12.966  1.00 68.83  ? 138 LYS D NZ  1 
ATOM   13554 N N   . LYS D 1 79  ? -45.343  -29.813 16.908  1.00 43.41  ? 139 LYS D N   1 
ATOM   13555 C CA  . LYS D 1 79  ? -46.684  -29.205 16.922  1.00 40.88  ? 139 LYS D CA  1 
ATOM   13556 C C   . LYS D 1 79  ? -46.575  -27.693 16.748  1.00 40.30  ? 139 LYS D C   1 
ATOM   13557 O O   . LYS D 1 79  ? -47.287  -27.162 15.891  1.00 42.97  ? 139 LYS D O   1 
ATOM   13558 C CB  . LYS D 1 79  ? -47.435  -29.499 18.220  1.00 47.06  ? 139 LYS D CB  1 
ATOM   13559 C CG  . LYS D 1 79  ? -48.828  -28.876 18.235  1.00 50.80  ? 139 LYS D CG  1 
ATOM   13560 C CD  . LYS D 1 79  ? -49.871  -29.610 19.033  1.00 55.44  ? 139 LYS D CD  1 
ATOM   13561 C CE  . LYS D 1 79  ? -49.921  -29.166 20.473  1.00 61.51  ? 139 LYS D CE  1 
ATOM   13562 N NZ  . LYS D 1 79  ? -50.893  -29.992 21.243  1.00 70.28  ? 139 LYS D NZ  1 
ATOM   13563 N N   . PHE D 1 80  ? -45.755  -27.005 17.538  1.00 42.70  ? 140 PHE D N   1 
ATOM   13564 C CA  . PHE D 1 80  ? -45.615  -25.531 17.410  1.00 48.22  ? 140 PHE D CA  1 
ATOM   13565 C C   . PHE D 1 80  ? -45.058  -25.212 16.019  1.00 53.67  ? 140 PHE D C   1 
ATOM   13566 O O   . PHE D 1 80  ? -45.550  -24.239 15.386  1.00 69.93  ? 140 PHE D O   1 
ATOM   13567 C CB  . PHE D 1 80  ? -44.764  -24.885 18.504  1.00 41.76  ? 140 PHE D CB  1 
ATOM   13568 C CG  . PHE D 1 80  ? -44.932  -23.382 18.541  1.00 41.83  ? 140 PHE D CG  1 
ATOM   13569 C CD1 . PHE D 1 80  ? -44.046  -22.544 17.879  1.00 39.36  ? 140 PHE D CD1 1 
ATOM   13570 C CD2 . PHE D 1 80  ? -46.010  -22.782 19.183  1.00 45.53  ? 140 PHE D CD2 1 
ATOM   13571 C CE1 . PHE D 1 80  ? -44.196  -21.150 17.918  1.00 43.81  ? 140 PHE D CE1 1 
ATOM   13572 C CE2 . PHE D 1 80  ? -46.160  -21.394 19.198  1.00 44.14  ? 140 PHE D CE2 1 
ATOM   13573 C CZ  . PHE D 1 80  ? -45.248  -20.568 18.575  1.00 38.01  ? 140 PHE D CZ  1 
ATOM   13574 N N   . MET D 1 81  ? -44.068  -25.987 15.554  1.00 53.18  ? 141 MET D N   1 
ATOM   13575 C CA  . MET D 1 81  ? -43.404  -25.730 14.253  1.00 52.26  ? 141 MET D CA  1 
ATOM   13576 C C   . MET D 1 81  ? -44.504  -25.783 13.175  1.00 53.67  ? 141 MET D C   1 
ATOM   13577 O O   . MET D 1 81  ? -44.629  -24.836 12.370  1.00 48.57  ? 141 MET D O   1 
ATOM   13578 C CB  . MET D 1 81  ? -42.271  -26.739 13.983  1.00 55.02  ? 141 MET D CB  1 
ATOM   13579 C CG  . MET D 1 81  ? -40.883  -26.405 14.592  1.00 55.25  ? 141 MET D CG  1 
ATOM   13580 S SD  . MET D 1 81  ? -40.333  -24.645 14.379  1.00 66.62  ? 141 MET D SD  1 
ATOM   13581 C CE  . MET D 1 81  ? -39.830  -24.656 12.659  1.00 60.98  ? 141 MET D CE  1 
ATOM   13582 N N   . ASN D 1 82  ? -45.347  -26.812 13.229  1.00 66.22  ? 142 ASN D N   1 
ATOM   13583 C CA  . ASN D 1 82  ? -46.436  -27.038 12.245  1.00 63.31  ? 142 ASN D CA  1 
ATOM   13584 C C   . ASN D 1 82  ? -47.347  -25.799 12.173  1.00 59.37  ? 142 ASN D C   1 
ATOM   13585 O O   . ASN D 1 82  ? -47.573  -25.326 11.074  1.00 57.29  ? 142 ASN D O   1 
ATOM   13586 C CB  . ASN D 1 82  ? -47.190  -28.325 12.546  1.00 60.76  ? 142 ASN D CB  1 
ATOM   13587 C CG  . ASN D 1 82  ? -47.954  -28.718 11.312  1.00 68.28  ? 142 ASN D CG  1 
ATOM   13588 O OD1 . ASN D 1 82  ? -48.869  -27.990 10.944  1.00 69.24  ? 142 ASN D OD1 1 
ATOM   13589 N ND2 . ASN D 1 82  ? -47.514  -29.764 10.619  1.00 73.74  ? 142 ASN D ND2 1 
ATOM   13590 N N   . THR D 1 83  ? -47.815  -25.267 13.306  1.00 57.59  ? 143 THR D N   1 
ATOM   13591 C CA  . THR D 1 83  ? -48.734  -24.089 13.365  1.00 60.13  ? 143 THR D CA  1 
ATOM   13592 C C   . THR D 1 83  ? -47.972  -22.779 13.102  1.00 54.77  ? 143 THR D C   1 
ATOM   13593 O O   . THR D 1 83  ? -48.605  -21.766 12.750  1.00 50.55  ? 143 THR D O   1 
ATOM   13594 C CB  . THR D 1 83  ? -49.528  -24.012 14.686  1.00 68.15  ? 143 THR D CB  1 
ATOM   13595 O OG1 . THR D 1 83  ? -48.663  -24.096 15.820  1.00 60.48  ? 143 THR D OG1 1 
ATOM   13596 C CG2 . THR D 1 83  ? -50.588  -25.089 14.787  1.00 68.70  ? 143 THR D CG2 1 
ATOM   13597 N N   . LEU D 1 84  ? -46.657  -22.764 13.254  1.00 55.45  ? 144 LEU D N   1 
ATOM   13598 C CA  . LEU D 1 84  ? -45.884  -21.534 12.979  1.00 56.57  ? 144 LEU D CA  1 
ATOM   13599 C C   . LEU D 1 84  ? -45.835  -21.284 11.466  1.00 60.98  ? 144 LEU D C   1 
ATOM   13600 O O   . LEU D 1 84  ? -45.819  -20.109 11.044  1.00 59.30  ? 144 LEU D O   1 
ATOM   13601 C CB  . LEU D 1 84  ? -44.487  -21.687 13.563  1.00 55.40  ? 144 LEU D CB  1 
ATOM   13602 C CG  . LEU D 1 84  ? -43.665  -20.401 13.532  1.00 59.25  ? 144 LEU D CG  1 
ATOM   13603 C CD1 . LEU D 1 84  ? -44.347  -19.242 14.285  1.00 53.49  ? 144 LEU D CD1 1 
ATOM   13604 C CD2 . LEU D 1 84  ? -42.286  -20.705 14.089  1.00 61.17  ? 144 LEU D CD2 1 
ATOM   13605 N N   . ARG D 1 85  ? -45.814  -22.356 10.684  1.00 67.72  ? 145 ARG D N   1 
ATOM   13606 C CA  . ARG D 1 85  ? -45.667  -22.297 9.211   1.00 70.03  ? 145 ARG D CA  1 
ATOM   13607 C C   . ARG D 1 85  ? -46.988  -21.877 8.555   1.00 65.87  ? 145 ARG D C   1 
ATOM   13608 O O   . ARG D 1 85  ? -46.926  -21.525 7.367   1.00 72.59  ? 145 ARG D O   1 
ATOM   13609 C CB  . ARG D 1 85  ? -45.215  -23.652 8.661   1.00 73.01  ? 145 ARG D CB  1 
ATOM   13610 C CG  . ARG D 1 85  ? -43.835  -24.070 9.122   1.00 80.59  ? 145 ARG D CG  1 
ATOM   13611 C CD  . ARG D 1 85  ? -43.495  -25.437 8.560   1.00 91.21  ? 145 ARG D CD  1 
ATOM   13612 N NE  . ARG D 1 85  ? -42.353  -25.975 9.285   1.00 103.33 ? 145 ARG D NE  1 
ATOM   13613 C CZ  . ARG D 1 85  ? -42.327  -27.153 9.901   1.00 109.73 ? 145 ARG D CZ  1 
ATOM   13614 N NH1 . ARG D 1 85  ? -43.380  -27.964 9.860   1.00 99.15  ? 145 ARG D NH1 1 
ATOM   13615 N NH2 . ARG D 1 85  ? -41.238  -27.492 10.578  1.00 112.90 ? 145 ARG D NH2 1 
ATOM   13616 N N   . GLN D 1 86  ? -48.124  -21.909 9.257   1.00 61.00  ? 146 GLN D N   1 
ATOM   13617 C CA  . GLN D 1 86  ? -49.407  -21.482 8.642   1.00 54.62  ? 146 GLN D CA  1 
ATOM   13618 C C   . GLN D 1 86  ? -49.534  -19.959 8.730   1.00 56.04  ? 146 GLN D C   1 
ATOM   13619 O O   . GLN D 1 86  ? -50.226  -19.408 7.900   1.00 52.66  ? 146 GLN D O   1 
ATOM   13620 C CB  . GLN D 1 86  ? -50.601  -22.204 9.244   1.00 55.10  ? 146 GLN D CB  1 
ATOM   13621 C CG  . GLN D 1 86  ? -51.039  -23.410 8.418   1.00 56.99  ? 146 GLN D CG  1 
ATOM   13622 C CD  . GLN D 1 86  ? -50.794  -24.692 9.159   1.00 62.23  ? 146 GLN D CD  1 
ATOM   13623 O OE1 . GLN D 1 86  ? -49.675  -24.946 9.588   1.00 80.71  ? 146 GLN D OE1 1 
ATOM   13624 N NE2 . GLN D 1 86  ? -51.846  -25.475 9.347   1.00 64.60  ? 146 GLN D NE2 1 
ATOM   13625 N N   . TYR D 1 87  ? -48.830  -19.295 9.641   1.00 57.02  ? 147 TYR D N   1 
ATOM   13626 C CA  . TYR D 1 87  ? -48.777  -17.808 9.666   1.00 59.85  ? 147 TYR D CA  1 
ATOM   13627 C C   . TYR D 1 87  ? -47.969  -17.405 8.434   1.00 68.67  ? 147 TYR D C   1 
ATOM   13628 O O   . TYR D 1 87  ? -46.980  -18.069 8.106   1.00 75.54  ? 147 TYR D O   1 
ATOM   13629 C CB  . TYR D 1 87  ? -48.233  -17.269 10.997  1.00 56.25  ? 147 TYR D CB  1 
ATOM   13630 C CG  . TYR D 1 87  ? -49.176  -17.495 12.145  1.00 59.47  ? 147 TYR D CG  1 
ATOM   13631 C CD1 . TYR D 1 87  ? -50.308  -16.714 12.271  1.00 57.24  ? 147 TYR D CD1 1 
ATOM   13632 C CD2 . TYR D 1 87  ? -49.019  -18.567 13.022  1.00 63.16  ? 147 TYR D CD2 1 
ATOM   13633 C CE1 . TYR D 1 87  ? -51.249  -16.970 13.255  1.00 63.33  ? 147 TYR D CE1 1 
ATOM   13634 C CE2 . TYR D 1 87  ? -49.961  -18.840 14.006  1.00 60.20  ? 147 TYR D CE2 1 
ATOM   13635 C CZ  . TYR D 1 87  ? -51.085  -18.034 14.123  1.00 63.89  ? 147 TYR D CZ  1 
ATOM   13636 O OH  . TYR D 1 87  ? -52.065  -18.198 15.070  1.00 68.24  ? 147 TYR D OH  1 
ATOM   13637 N N   . GLN D 1 88  ? -48.360  -16.357 7.739   1.00 71.82  ? 148 GLN D N   1 
ATOM   13638 C CA  . GLN D 1 88  ? -47.808  -16.214 6.382   1.00 74.84  ? 148 GLN D CA  1 
ATOM   13639 C C   . GLN D 1 88  ? -47.068  -14.882 6.262   1.00 70.14  ? 148 GLN D C   1 
ATOM   13640 O O   . GLN D 1 88  ? -46.095  -14.906 5.531   1.00 77.06  ? 148 GLN D O   1 
ATOM   13641 C CB  . GLN D 1 88  ? -48.913  -16.648 5.435   1.00 86.32  ? 148 GLN D CB  1 
ATOM   13642 C CG  . GLN D 1 88  ? -50.177  -15.843 5.552   1.00 97.80  ? 148 GLN D CG  1 
ATOM   13643 C CD  . GLN D 1 88  ? -50.118  -14.912 4.372   1.00 117.55 ? 148 GLN D CD  1 
ATOM   13644 O OE1 . GLN D 1 88  ? -49.357  -13.944 4.369   1.00 129.81 ? 148 GLN D OE1 1 
ATOM   13645 N NE2 . GLN D 1 88  ? -50.856  -15.249 3.321   1.00 111.12 ? 148 GLN D NE2 1 
ATOM   13646 N N   . THR D 1 89  ? -47.343  -13.847 7.064   1.00 62.83  ? 149 THR D N   1 
ATOM   13647 C CA  . THR D 1 89  ? -46.347  -12.755 7.222   1.00 62.76  ? 149 THR D CA  1 
ATOM   13648 C C   . THR D 1 89  ? -45.284  -13.251 8.209   1.00 74.55  ? 149 THR D C   1 
ATOM   13649 O O   . THR D 1 89  ? -45.520  -14.173 9.013   1.00 68.70  ? 149 THR D O   1 
ATOM   13650 C CB  . THR D 1 89  ? -46.989  -11.403 7.538   1.00 65.34  ? 149 THR D CB  1 
ATOM   13651 O OG1 . THR D 1 89  ? -47.323  -11.293 8.922   1.00 58.41  ? 149 THR D OG1 1 
ATOM   13652 C CG2 . THR D 1 89  ? -48.245  -11.166 6.729   1.00 71.61  ? 149 THR D CG2 1 
ATOM   13653 N N   . PRO D 1 90  ? -44.024  -12.749 8.100   1.00 70.57  ? 150 PRO D N   1 
ATOM   13654 C CA  . PRO D 1 90  ? -43.015  -13.001 9.127   1.00 63.86  ? 150 PRO D CA  1 
ATOM   13655 C C   . PRO D 1 90  ? -43.437  -12.413 10.477  1.00 58.56  ? 150 PRO D C   1 
ATOM   13656 O O   . PRO D 1 90  ? -43.347  -13.142 11.432  1.00 57.22  ? 150 PRO D O   1 
ATOM   13657 C CB  . PRO D 1 90  ? -41.758  -12.330 8.569   1.00 58.61  ? 150 PRO D CB  1 
ATOM   13658 C CG  . PRO D 1 90  ? -41.997  -12.361 7.083   1.00 54.67  ? 150 PRO D CG  1 
ATOM   13659 C CD  . PRO D 1 90  ? -43.467  -12.035 6.947   1.00 57.94  ? 150 PRO D CD  1 
ATOM   13660 N N   . LEU D 1 91  ? -43.907  -11.153 10.504  1.00 56.17  ? 151 LEU D N   1 
ATOM   13661 C CA  . LEU D 1 91  ? -44.425  -10.468 11.725  1.00 46.96  ? 151 LEU D CA  1 
ATOM   13662 C C   . LEU D 1 91  ? -45.414  -11.369 12.480  1.00 46.64  ? 151 LEU D C   1 
ATOM   13663 O O   . LEU D 1 91  ? -45.304  -11.455 13.685  1.00 46.29  ? 151 LEU D O   1 
ATOM   13664 C CB  . LEU D 1 91  ? -45.098  -9.149  11.351  1.00 42.32  ? 151 LEU D CB  1 
ATOM   13665 C CG  . LEU D 1 91  ? -45.555  -8.296  12.519  1.00 37.65  ? 151 LEU D CG  1 
ATOM   13666 C CD1 . LEU D 1 91  ? -44.404  -8.126  13.472  1.00 42.16  ? 151 LEU D CD1 1 
ATOM   13667 C CD2 . LEU D 1 91  ? -46.029  -6.941  12.046  1.00 41.49  ? 151 LEU D CD2 1 
ATOM   13668 N N   . GLN D 1 92  ? -46.330  -12.057 11.804  1.00 49.40  ? 152 GLN D N   1 
ATOM   13669 C CA  . GLN D 1 92  ? -47.259  -13.029 12.456  1.00 47.44  ? 152 GLN D CA  1 
ATOM   13670 C C   . GLN D 1 92  ? -46.479  -14.166 13.124  1.00 38.76  ? 152 GLN D C   1 
ATOM   13671 O O   . GLN D 1 92  ? -46.914  -14.590 14.183  1.00 45.66  ? 152 GLN D O   1 
ATOM   13672 C CB  . GLN D 1 92  ? -48.275  -13.603 11.466  1.00 52.20  ? 152 GLN D CB  1 
ATOM   13673 C CG  . GLN D 1 92  ? -49.397  -12.642 11.104  1.00 56.00  ? 152 GLN D CG  1 
ATOM   13674 C CD  . GLN D 1 92  ? -50.162  -13.109 9.887   1.00 61.03  ? 152 GLN D CD  1 
ATOM   13675 O OE1 . GLN D 1 92  ? -49.981  -14.223 9.384   1.00 79.26  ? 152 GLN D OE1 1 
ATOM   13676 N NE2 . GLN D 1 92  ? -51.060  -12.264 9.414   1.00 66.09  ? 152 GLN D NE2 1 
ATOM   13677 N N   . ARG D 1 93  ? -45.391  -14.656 12.543  1.00 37.06  ? 153 ARG D N   1 
ATOM   13678 C CA  . ARG D 1 93  ? -44.567  -15.710 13.194  1.00 45.62  ? 153 ARG D CA  1 
ATOM   13679 C C   . ARG D 1 93  ? -43.753  -15.118 14.362  1.00 45.43  ? 153 ARG D C   1 
ATOM   13680 O O   . ARG D 1 93  ? -43.492  -15.866 15.325  1.00 45.49  ? 153 ARG D O   1 
ATOM   13681 C CB  . ARG D 1 93  ? -43.637  -16.380 12.195  1.00 49.29  ? 153 ARG D CB  1 
ATOM   13682 C CG  . ARG D 1 93  ? -44.350  -17.206 11.148  1.00 51.47  ? 153 ARG D CG  1 
ATOM   13683 C CD  . ARG D 1 93  ? -43.384  -17.556 10.065  1.00 60.25  ? 153 ARG D CD  1 
ATOM   13684 N NE  . ARG D 1 93  ? -43.979  -18.587 9.237   1.00 63.60  ? 153 ARG D NE  1 
ATOM   13685 C CZ  . ARG D 1 93  ? -43.854  -18.622 7.922   1.00 81.69  ? 153 ARG D CZ  1 
ATOM   13686 N NH1 . ARG D 1 93  ? -43.155  -17.693 7.290   1.00 100.80 ? 153 ARG D NH1 1 
ATOM   13687 N NH2 . ARG D 1 93  ? -44.414  -19.579 7.212   1.00 85.20  ? 153 ARG D NH2 1 
ATOM   13688 N N   . TYR D 1 94  ? -43.359  -13.842 14.296  1.00 47.40  ? 154 TYR D N   1 
ATOM   13689 C CA  . TYR D 1 94  ? -42.707  -13.111 15.428  1.00 51.39  ? 154 TYR D CA  1 
ATOM   13690 C C   . TYR D 1 94  ? -43.678  -13.019 16.614  1.00 55.89  ? 154 TYR D C   1 
ATOM   13691 O O   . TYR D 1 94  ? -43.242  -13.203 17.756  1.00 57.98  ? 154 TYR D O   1 
ATOM   13692 C CB  . TYR D 1 94  ? -42.259  -11.691 15.046  1.00 53.79  ? 154 TYR D CB  1 
ATOM   13693 C CG  . TYR D 1 94  ? -41.827  -10.817 16.202  1.00 48.27  ? 154 TYR D CG  1 
ATOM   13694 C CD1 . TYR D 1 94  ? -42.730  -9.959  16.800  1.00 47.80  ? 154 TYR D CD1 1 
ATOM   13695 C CD2 . TYR D 1 94  ? -40.542  -10.859 16.715  1.00 48.32  ? 154 TYR D CD2 1 
ATOM   13696 C CE1 . TYR D 1 94  ? -42.372  -9.171  17.876  1.00 52.32  ? 154 TYR D CE1 1 
ATOM   13697 C CE2 . TYR D 1 94  ? -40.166  -10.067 17.785  1.00 53.59  ? 154 TYR D CE2 1 
ATOM   13698 C CZ  . TYR D 1 94  ? -41.087  -9.218  18.373  1.00 56.06  ? 154 TYR D CZ  1 
ATOM   13699 O OH  . TYR D 1 94  ? -40.768  -8.440  19.452  1.00 64.03  ? 154 TYR D OH  1 
ATOM   13700 N N   . ILE D 1 95  ? -44.948  -12.714 16.344  1.00 55.53  ? 155 ILE D N   1 
ATOM   13701 C CA  . ILE D 1 95  ? -45.987  -12.578 17.398  1.00 56.58  ? 155 ILE D CA  1 
ATOM   13702 C C   . ILE D 1 95  ? -46.191  -13.954 18.037  1.00 54.57  ? 155 ILE D C   1 
ATOM   13703 O O   . ILE D 1 95  ? -46.268  -14.003 19.279  1.00 63.79  ? 155 ILE D O   1 
ATOM   13704 C CB  . ILE D 1 95  ? -47.294  -11.961 16.859  1.00 58.61  ? 155 ILE D CB  1 
ATOM   13705 C CG1 . ILE D 1 95  ? -47.050  -10.557 16.297  1.00 60.44  ? 155 ILE D CG1 1 
ATOM   13706 C CG2 . ILE D 1 95  ? -48.366  -11.936 17.938  1.00 59.71  ? 155 ILE D CG2 1 
ATOM   13707 C CD1 . ILE D 1 95  ? -48.257  -9.909  15.657  1.00 61.05  ? 155 ILE D CD1 1 
ATOM   13708 N N   . ALA D 1 96  ? -46.239  -15.024 17.240  1.00 47.83  ? 156 ALA D N   1 
ATOM   13709 C CA  . ALA D 1 96  ? -46.473  -16.398 17.750  1.00 51.06  ? 156 ALA D CA  1 
ATOM   13710 C C   . ALA D 1 96  ? -45.266  -16.833 18.587  1.00 55.36  ? 156 ALA D C   1 
ATOM   13711 O O   . ALA D 1 96  ? -45.453  -17.610 19.536  1.00 52.21  ? 156 ALA D O   1 
ATOM   13712 C CB  . ALA D 1 96  ? -46.747  -17.378 16.632  1.00 49.90  ? 156 ALA D CB  1 
ATOM   13713 N N   . MET D 1 97  ? -44.073  -16.333 18.246  1.00 57.36  ? 157 MET D N   1 
ATOM   13714 C CA  . MET D 1 97  ? -42.805  -16.697 18.921  1.00 56.43  ? 157 MET D CA  1 
ATOM   13715 C C   . MET D 1 97  ? -42.773  -16.006 20.278  1.00 53.13  ? 157 MET D C   1 
ATOM   13716 O O   . MET D 1 97  ? -42.525  -16.727 21.260  1.00 57.88  ? 157 MET D O   1 
ATOM   13717 C CB  . MET D 1 97  ? -41.594  -16.303 18.060  1.00 63.49  ? 157 MET D CB  1 
ATOM   13718 C CG  . MET D 1 97  ? -40.534  -17.367 17.876  1.00 66.54  ? 157 MET D CG  1 
ATOM   13719 S SD  . MET D 1 97  ? -41.107  -18.946 17.292  1.00 62.01  ? 157 MET D SD  1 
ATOM   13720 C CE  . MET D 1 97  ? -39.590  -19.847 17.564  1.00 65.51  ? 157 MET D CE  1 
ATOM   13721 N N   . MET D 1 98  ? -43.114  -14.705 20.338  1.00 59.36  ? 158 MET D N   1 
ATOM   13722 C CA  . MET D 1 98  ? -43.078  -13.868 21.580  1.00 58.16  ? 158 MET D CA  1 
ATOM   13723 C C   . MET D 1 98  ? -44.126  -14.383 22.552  1.00 57.52  ? 158 MET D C   1 
ATOM   13724 O O   . MET D 1 98  ? -43.779  -14.547 23.720  1.00 63.92  ? 158 MET D O   1 
ATOM   13725 C CB  . MET D 1 98  ? -43.296  -12.372 21.310  1.00 53.04  ? 158 MET D CB  1 
ATOM   13726 C CG  . MET D 1 98  ? -42.107  -11.727 20.559  1.00 60.53  ? 158 MET D CG  1 
ATOM   13727 S SD  . MET D 1 98  ? -40.473  -12.048 21.309  1.00 64.10  ? 158 MET D SD  1 
ATOM   13728 C CE  . MET D 1 98  ? -39.580  -13.014 20.073  1.00 64.21  ? 158 MET D CE  1 
ATOM   13729 N N   . ASN D 1 99  ? -45.325  -14.695 22.057  1.00 61.66  ? 159 ASN D N   1 
ATOM   13730 C CA  . ASN D 1 99  ? -46.397  -15.385 22.827  1.00 56.77  ? 159 ASN D CA  1 
ATOM   13731 C C   . ASN D 1 99  ? -45.864  -16.672 23.498  1.00 53.00  ? 159 ASN D C   1 
ATOM   13732 O O   . ASN D 1 99  ? -46.102  -16.813 24.701  1.00 61.63  ? 159 ASN D O   1 
ATOM   13733 C CB  . ASN D 1 99  ? -47.605  -15.664 21.937  1.00 65.03  ? 159 ASN D CB  1 
ATOM   13734 C CG  . ASN D 1 99  ? -48.901  -15.714 22.712  1.00 71.31  ? 159 ASN D CG  1 
ATOM   13735 O OD1 . ASN D 1 99  ? -49.427  -16.802 22.964  1.00 71.83  ? 159 ASN D OD1 1 
ATOM   13736 N ND2 . ASN D 1 99  ? -49.418  -14.550 23.089  1.00 73.56  ? 159 ASN D ND2 1 
ATOM   13737 N N   . LEU D 1 100 ? -45.185  -17.580 22.780  1.00 45.47  ? 160 LEU D N   1 
ATOM   13738 C CA  . LEU D 1 100 ? -44.664  -18.857 23.348  1.00 44.48  ? 160 LEU D CA  1 
ATOM   13739 C C   . LEU D 1 100 ? -43.574  -18.566 24.392  1.00 58.28  ? 160 LEU D C   1 
ATOM   13740 O O   . LEU D 1 100 ? -43.590  -19.194 25.493  1.00 60.78  ? 160 LEU D O   1 
ATOM   13741 C CB  . LEU D 1 100 ? -44.087  -19.727 22.239  1.00 44.89  ? 160 LEU D CB  1 
ATOM   13742 C CG  . LEU D 1 100 ? -43.457  -21.055 22.692  1.00 42.61  ? 160 LEU D CG  1 
ATOM   13743 C CD1 . LEU D 1 100 ? -44.454  -21.993 23.362  1.00 35.61  ? 160 LEU D CD1 1 
ATOM   13744 C CD2 . LEU D 1 100 ? -42.833  -21.751 21.509  1.00 50.80  ? 160 LEU D CD2 1 
ATOM   13745 N N   . GLN D 1 101 ? -42.652  -17.645 24.087  1.00 59.86  ? 161 GLN D N   1 
ATOM   13746 C CA  . GLN D 1 101 ? -41.591  -17.222 25.048  1.00 60.31  ? 161 GLN D CA  1 
ATOM   13747 C C   . GLN D 1 101 ? -42.233  -16.922 26.396  1.00 56.97  ? 161 GLN D C   1 
ATOM   13748 O O   . GLN D 1 101 ? -41.640  -17.334 27.420  1.00 59.14  ? 161 GLN D O   1 
ATOM   13749 C CB  . GLN D 1 101 ? -40.834  -15.995 24.540  1.00 58.96  ? 161 GLN D CB  1 
ATOM   13750 C CG  . GLN D 1 101 ? -39.622  -15.636 25.349  1.00 57.34  ? 161 GLN D CG  1 
ATOM   13751 C CD  . GLN D 1 101 ? -39.021  -14.365 24.784  1.00 69.62  ? 161 GLN D CD  1 
ATOM   13752 O OE1 . GLN D 1 101 ? -38.567  -14.325 23.632  1.00 84.21  ? 161 GLN D OE1 1 
ATOM   13753 N NE2 . GLN D 1 101 ? -39.062  -13.295 25.569  1.00 65.18  ? 161 GLN D NE2 1 
ATOM   13754 N N   . GLU D 1 102 ? -43.416  -16.290 26.362  1.00 54.69  ? 162 GLU D N   1 
ATOM   13755 C CA  . GLU D 1 102 ? -44.129  -15.745 27.542  1.00 54.38  ? 162 GLU D CA  1 
ATOM   13756 C C   . GLU D 1 102 ? -45.248  -16.694 27.995  1.00 49.29  ? 162 GLU D C   1 
ATOM   13757 O O   . GLU D 1 102 ? -46.171  -16.183 28.636  1.00 51.57  ? 162 GLU D O   1 
ATOM   13758 C CB  . GLU D 1 102 ? -44.702  -14.358 27.214  1.00 60.25  ? 162 GLU D CB  1 
ATOM   13759 C CG  . GLU D 1 102 ? -43.666  -13.338 26.762  1.00 63.91  ? 162 GLU D CG  1 
ATOM   13760 C CD  . GLU D 1 102 ? -42.600  -13.023 27.793  1.00 77.47  ? 162 GLU D CD  1 
ATOM   13761 O OE1 . GLU D 1 102 ? -42.964  -12.452 28.835  1.00 87.31  ? 162 GLU D OE1 1 
ATOM   13762 O OE2 . GLU D 1 102 ? -41.399  -13.272 27.517  1.00 84.16  ? 162 GLU D OE2 1 
ATOM   13763 N N   . THR D 1 103 ? -45.190  -17.998 27.700  1.00 44.60  ? 163 THR D N   1 
ATOM   13764 C CA  . THR D 1 103 ? -46.171  -18.996 28.222  1.00 52.73  ? 163 THR D CA  1 
ATOM   13765 C C   . THR D 1 103 ? -45.463  -20.289 28.635  1.00 52.51  ? 163 THR D C   1 
ATOM   13766 O O   . THR D 1 103 ? -45.916  -20.912 29.637  1.00 57.27  ? 163 THR D O   1 
ATOM   13767 C CB  . THR D 1 103 ? -47.333  -19.314 27.256  1.00 55.75  ? 163 THR D CB  1 
ATOM   13768 O OG1 . THR D 1 103 ? -46.954  -20.188 26.194  1.00 62.28  ? 163 THR D OG1 1 
ATOM   13769 C CG2 . THR D 1 103 ? -47.919  -18.079 26.622  1.00 60.84  ? 163 THR D CG2 1 
ATOM   13770 N N   . ASP D 1 104 ? -44.471  -20.706 27.845  1.00 50.18  ? 164 ASP D N   1 
ATOM   13771 C CA  . ASP D 1 104 ? -43.597  -21.870 28.114  1.00 48.58  ? 164 ASP D CA  1 
ATOM   13772 C C   . ASP D 1 104 ? -42.182  -21.510 27.632  1.00 54.78  ? 164 ASP D C   1 
ATOM   13773 O O   . ASP D 1 104 ? -41.894  -21.665 26.432  1.00 48.94  ? 164 ASP D O   1 
ATOM   13774 C CB  . ASP D 1 104 ? -44.185  -23.144 27.503  1.00 41.55  ? 164 ASP D CB  1 
ATOM   13775 C CG  . ASP D 1 104 ? -43.395  -24.414 27.830  1.00 42.45  ? 164 ASP D CG  1 
ATOM   13776 O OD1 . ASP D 1 104 ? -42.255  -24.340 28.379  1.00 45.40  ? 164 ASP D OD1 1 
ATOM   13777 O OD2 . ASP D 1 104 ? -43.899  -25.471 27.511  1.00 43.15  ? 164 ASP D OD2 1 
ATOM   13778 N N   . GLU D 1 105 ? -41.338  -21.057 28.561  1.00 59.24  ? 165 GLU D N   1 
ATOM   13779 C CA  . GLU D 1 105 ? -39.979  -20.508 28.307  1.00 59.50  ? 165 GLU D CA  1 
ATOM   13780 C C   . GLU D 1 105 ? -39.067  -21.663 27.887  1.00 55.14  ? 165 GLU D C   1 
ATOM   13781 O O   . GLU D 1 105 ? -38.277  -21.504 26.943  1.00 60.84  ? 165 GLU D O   1 
ATOM   13782 C CB  . GLU D 1 105 ? -39.556  -19.795 29.594  1.00 60.37  ? 165 GLU D CB  1 
ATOM   13783 C CG  . GLU D 1 105 ? -38.153  -19.267 29.658  1.00 60.95  ? 165 GLU D CG  1 
ATOM   13784 C CD  . GLU D 1 105 ? -37.642  -19.286 31.088  1.00 62.34  ? 165 GLU D CD  1 
ATOM   13785 O OE1 . GLU D 1 105 ? -37.842  -18.227 31.799  1.00 57.31  ? 165 GLU D OE1 1 
ATOM   13786 O OE2 . GLU D 1 105 ? -37.068  -20.379 31.476  1.00 52.46  ? 165 GLU D OE2 1 
ATOM   13787 N N   . ARG D 1 106 ? -39.213  -22.818 28.520  1.00 51.62  ? 166 ARG D N   1 
ATOM   13788 C CA  . ARG D 1 106 ? -38.368  -23.984 28.187  1.00 64.34  ? 166 ARG D CA  1 
ATOM   13789 C C   . ARG D 1 106 ? -38.690  -24.521 26.787  1.00 67.18  ? 166 ARG D C   1 
ATOM   13790 O O   . ARG D 1 106 ? -37.754  -24.886 26.059  1.00 71.58  ? 166 ARG D O   1 
ATOM   13791 C CB  . ARG D 1 106 ? -38.588  -25.060 29.236  1.00 90.97  ? 166 ARG D CB  1 
ATOM   13792 C CG  . ARG D 1 106 ? -37.905  -24.750 30.558  1.00 104.13 ? 166 ARG D CG  1 
ATOM   13793 C CD  . ARG D 1 106 ? -37.500  -26.099 31.129  1.00 116.44 ? 166 ARG D CD  1 
ATOM   13794 N NE  . ARG D 1 106 ? -36.066  -26.324 31.209  1.00 131.37 ? 166 ARG D NE  1 
ATOM   13795 C CZ  . ARG D 1 106 ? -35.277  -25.914 32.198  1.00 110.15 ? 166 ARG D CZ  1 
ATOM   13796 N NH1 . ARG D 1 106 ? -35.778  -25.201 33.195  1.00 92.16  ? 166 ARG D NH1 1 
ATOM   13797 N NH2 . ARG D 1 106 ? -33.994  -26.230 32.177  1.00 102.97 ? 166 ARG D NH2 1 
ATOM   13798 N N   . LEU D 1 107 ? -39.966  -24.588 26.400  1.00 66.29  ? 167 LEU D N   1 
ATOM   13799 C CA  . LEU D 1 107 ? -40.361  -25.038 25.035  1.00 56.07  ? 167 LEU D CA  1 
ATOM   13800 C C   . LEU D 1 107 ? -39.867  -24.020 24.003  1.00 48.37  ? 167 LEU D C   1 
ATOM   13801 O O   . LEU D 1 107 ? -39.334  -24.437 22.955  1.00 42.80  ? 167 LEU D O   1 
ATOM   13802 C CB  . LEU D 1 107 ? -41.878  -25.202 24.953  1.00 58.43  ? 167 LEU D CB  1 
ATOM   13803 C CG  . LEU D 1 107 ? -42.403  -25.606 23.568  1.00 60.42  ? 167 LEU D CG  1 
ATOM   13804 C CD1 . LEU D 1 107 ? -41.775  -26.922 23.132  1.00 58.30  ? 167 LEU D CD1 1 
ATOM   13805 C CD2 . LEU D 1 107 ? -43.924  -25.704 23.547  1.00 56.37  ? 167 LEU D CD2 1 
ATOM   13806 N N   . PHE D 1 108 ? -40.021  -22.727 24.305  1.00 42.33  ? 168 PHE D N   1 
ATOM   13807 C CA  . PHE D 1 108 ? -39.579  -21.606 23.442  1.00 37.08  ? 168 PHE D CA  1 
ATOM   13808 C C   . PHE D 1 108 ? -38.096  -21.729 23.134  1.00 37.10  ? 168 PHE D C   1 
ATOM   13809 O O   . PHE D 1 108 ? -37.744  -21.594 21.956  1.00 37.77  ? 168 PHE D O   1 
ATOM   13810 C CB  . PHE D 1 108 ? -39.823  -20.260 24.105  1.00 36.63  ? 168 PHE D CB  1 
ATOM   13811 C CG  . PHE D 1 108 ? -39.158  -19.118 23.397  1.00 32.73  ? 168 PHE D CG  1 
ATOM   13812 C CD1 . PHE D 1 108 ? -39.767  -18.510 22.328  1.00 37.03  ? 168 PHE D CD1 1 
ATOM   13813 C CD2 . PHE D 1 108 ? -37.940  -18.654 23.815  1.00 33.12  ? 168 PHE D CD2 1 
ATOM   13814 C CE1 . PHE D 1 108 ? -39.152  -17.447 21.684  1.00 46.43  ? 168 PHE D CE1 1 
ATOM   13815 C CE2 . PHE D 1 108 ? -37.328  -17.600 23.172  1.00 39.33  ? 168 PHE D CE2 1 
ATOM   13816 C CZ  . PHE D 1 108 ? -37.930  -16.994 22.103  1.00 38.80  ? 168 PHE D CZ  1 
ATOM   13817 N N   . TYR D 1 109 ? -37.261  -21.943 24.155  1.00 39.28  ? 169 TYR D N   1 
ATOM   13818 C CA  . TYR D 1 109 ? -35.790  -22.002 23.955  1.00 41.87  ? 169 TYR D CA  1 
ATOM   13819 C C   . TYR D 1 109 ? -35.447  -23.335 23.276  1.00 47.19  ? 169 TYR D C   1 
ATOM   13820 O O   . TYR D 1 109 ? -34.746  -23.271 22.251  1.00 50.02  ? 169 TYR D O   1 
ATOM   13821 C CB  . TYR D 1 109 ? -35.011  -21.656 25.227  1.00 35.35  ? 169 TYR D CB  1 
ATOM   13822 C CG  . TYR D 1 109 ? -35.066  -20.179 25.547  1.00 36.01  ? 169 TYR D CG  1 
ATOM   13823 C CD1 . TYR D 1 109 ? -34.533  -19.222 24.702  1.00 34.02  ? 169 TYR D CD1 1 
ATOM   13824 C CD2 . TYR D 1 109 ? -35.733  -19.715 26.664  1.00 37.42  ? 169 TYR D CD2 1 
ATOM   13825 C CE1 . TYR D 1 109 ? -34.608  -17.864 24.988  1.00 32.94  ? 169 TYR D CE1 1 
ATOM   13826 C CE2 . TYR D 1 109 ? -35.829  -18.365 26.964  1.00 34.18  ? 169 TYR D CE2 1 
ATOM   13827 C CZ  . TYR D 1 109 ? -35.248  -17.438 26.132  1.00 35.75  ? 169 TYR D CZ  1 
ATOM   13828 O OH  . TYR D 1 109 ? -35.349  -16.112 26.434  1.00 43.89  ? 169 TYR D OH  1 
ATOM   13829 N N   . LYS D 1 110 ? -35.979  -24.473 23.726  1.00 48.33  ? 170 LYS D N   1 
ATOM   13830 C CA  . LYS D 1 110 ? -35.632  -25.799 23.132  1.00 55.93  ? 170 LYS D CA  1 
ATOM   13831 C C   . LYS D 1 110 ? -36.008  -25.821 21.643  1.00 52.01  ? 170 LYS D C   1 
ATOM   13832 O O   . LYS D 1 110 ? -35.239  -26.356 20.823  1.00 50.15  ? 170 LYS D O   1 
ATOM   13833 C CB  . LYS D 1 110 ? -36.301  -26.925 23.922  1.00 63.87  ? 170 LYS D CB  1 
ATOM   13834 C CG  . LYS D 1 110 ? -35.464  -28.180 24.069  1.00 74.51  ? 170 LYS D CG  1 
ATOM   13835 C CD  . LYS D 1 110 ? -35.580  -29.139 22.948  1.00 73.25  ? 170 LYS D CD  1 
ATOM   13836 C CE  . LYS D 1 110 ? -34.693  -30.323 23.234  1.00 68.57  ? 170 LYS D CE  1 
ATOM   13837 N NZ  . LYS D 1 110 ? -34.653  -31.204 22.062  1.00 78.95  ? 170 LYS D NZ  1 
ATOM   13838 N N   . LEU D 1 111 ? -37.111  -25.173 21.292  1.00 56.40  ? 171 LEU D N   1 
ATOM   13839 C CA  . LEU D 1 111 ? -37.560  -25.057 19.880  1.00 58.93  ? 171 LEU D CA  1 
ATOM   13840 C C   . LEU D 1 111 ? -36.564  -24.169 19.122  1.00 53.72  ? 171 LEU D C   1 
ATOM   13841 O O   . LEU D 1 111 ? -36.009  -24.644 18.144  1.00 56.00  ? 171 LEU D O   1 
ATOM   13842 C CB  . LEU D 1 111 ? -38.983  -24.478 19.874  1.00 64.10  ? 171 LEU D CB  1 
ATOM   13843 C CG  . LEU D 1 111 ? -39.568  -24.117 18.509  1.00 66.72  ? 171 LEU D CG  1 
ATOM   13844 C CD1 . LEU D 1 111 ? -40.865  -24.866 18.291  1.00 64.82  ? 171 LEU D CD1 1 
ATOM   13845 C CD2 . LEU D 1 111 ? -39.769  -22.605 18.384  1.00 67.15  ? 171 LEU D CD2 1 
ATOM   13846 N N   . LEU D 1 112 ? -36.344  -22.936 19.594  1.00 54.22  ? 172 LEU D N   1 
ATOM   13847 C CA  . LEU D 1 112 ? -35.463  -21.929 18.953  1.00 51.46  ? 172 LEU D CA  1 
ATOM   13848 C C   . LEU D 1 112 ? -34.091  -22.543 18.665  1.00 50.59  ? 172 LEU D C   1 
ATOM   13849 O O   . LEU D 1 112 ? -33.633  -22.403 17.546  1.00 50.63  ? 172 LEU D O   1 
ATOM   13850 C CB  . LEU D 1 112 ? -35.313  -20.694 19.847  1.00 50.29  ? 172 LEU D CB  1 
ATOM   13851 C CG  . LEU D 1 112 ? -34.506  -19.563 19.220  1.00 47.78  ? 172 LEU D CG  1 
ATOM   13852 C CD1 . LEU D 1 112 ? -35.128  -19.115 17.933  1.00 46.14  ? 172 LEU D CD1 1 
ATOM   13853 C CD2 . LEU D 1 112 ? -34.405  -18.369 20.140  1.00 56.40  ? 172 LEU D CD2 1 
ATOM   13854 N N   . ILE D 1 113 ? -33.465  -23.222 19.627  1.00 51.74  ? 173 ILE D N   1 
ATOM   13855 C CA  . ILE D 1 113 ? -32.120  -23.855 19.443  1.00 49.85  ? 173 ILE D CA  1 
ATOM   13856 C C   . ILE D 1 113 ? -32.223  -24.901 18.324  1.00 51.74  ? 173 ILE D C   1 
ATOM   13857 O O   . ILE D 1 113 ? -31.508  -24.745 17.308  1.00 59.32  ? 173 ILE D O   1 
ATOM   13858 C CB  . ILE D 1 113 ? -31.584  -24.423 20.769  1.00 48.41  ? 173 ILE D CB  1 
ATOM   13859 C CG1 . ILE D 1 113 ? -31.324  -23.277 21.765  1.00 54.26  ? 173 ILE D CG1 1 
ATOM   13860 C CG2 . ILE D 1 113 ? -30.331  -25.245 20.556  1.00 50.33  ? 173 ILE D CG2 1 
ATOM   13861 C CD1 . ILE D 1 113 ? -31.169  -23.700 23.217  1.00 49.83  ? 173 ILE D CD1 1 
ATOM   13862 N N   . ASP D 1 114 ? -33.103  -25.893 18.466  1.00 49.91  ? 174 ASP D N   1 
ATOM   13863 C CA  . ASP D 1 114 ? -33.180  -27.054 17.532  1.00 51.42  ? 174 ASP D CA  1 
ATOM   13864 C C   . ASP D 1 114 ? -33.559  -26.603 16.117  1.00 50.82  ? 174 ASP D C   1 
ATOM   13865 O O   . ASP D 1 114 ? -33.425  -27.432 15.217  1.00 59.67  ? 174 ASP D O   1 
ATOM   13866 C CB  . ASP D 1 114 ? -34.183  -28.104 18.011  1.00 56.35  ? 174 ASP D CB  1 
ATOM   13867 C CG  . ASP D 1 114 ? -33.821  -28.711 19.353  1.00 59.32  ? 174 ASP D CG  1 
ATOM   13868 O OD1 . ASP D 1 114 ? -32.766  -28.348 19.889  1.00 60.21  ? 174 ASP D OD1 1 
ATOM   13869 O OD2 . ASP D 1 114 ? -34.614  -29.522 19.866  1.00 69.91  ? 174 ASP D OD2 1 
ATOM   13870 N N   . ASN D 1 115 ? -34.039  -25.367 15.934  1.00 52.51  ? 175 ASN D N   1 
ATOM   13871 C CA  . ASN D 1 115 ? -34.578  -24.853 14.644  1.00 60.66  ? 175 ASN D CA  1 
ATOM   13872 C C   . ASN D 1 115 ? -33.994  -23.450 14.388  1.00 66.01  ? 175 ASN D C   1 
ATOM   13873 O O   . ASN D 1 115 ? -34.697  -22.602 13.787  1.00 74.23  ? 175 ASN D O   1 
ATOM   13874 C CB  . ASN D 1 115 ? -36.112  -24.862 14.616  1.00 53.35  ? 175 ASN D CB  1 
ATOM   13875 C CG  . ASN D 1 115 ? -36.717  -26.252 14.710  1.00 56.80  ? 175 ASN D CG  1 
ATOM   13876 O OD1 . ASN D 1 115 ? -36.925  -26.770 15.797  1.00 64.83  ? 175 ASN D OD1 1 
ATOM   13877 N ND2 . ASN D 1 115 ? -37.060  -26.872 13.595  1.00 54.17  ? 175 ASN D ND2 1 
ATOM   13878 N N   . VAL D 1 116 ? -32.747  -23.208 14.807  1.00 63.31  ? 176 VAL D N   1 
ATOM   13879 C CA  . VAL D 1 116 ? -32.187  -21.828 14.943  1.00 56.97  ? 176 VAL D CA  1 
ATOM   13880 C C   . VAL D 1 116 ? -32.059  -21.143 13.575  1.00 55.39  ? 176 VAL D C   1 
ATOM   13881 O O   . VAL D 1 116 ? -32.245  -19.909 13.514  1.00 49.67  ? 176 VAL D O   1 
ATOM   13882 C CB  . VAL D 1 116 ? -30.852  -21.812 15.707  1.00 54.68  ? 176 VAL D CB  1 
ATOM   13883 C CG1 . VAL D 1 116 ? -29.847  -22.807 15.149  1.00 56.70  ? 176 VAL D CG1 1 
ATOM   13884 C CG2 . VAL D 1 116 ? -30.271  -20.397 15.757  1.00 58.23  ? 176 VAL D CG2 1 
ATOM   13885 N N   . VAL D 1 117 ? -31.717  -21.901 12.534  1.00 55.88  ? 177 VAL D N   1 
ATOM   13886 C CA  . VAL D 1 117 ? -31.468  -21.362 11.163  1.00 56.68  ? 177 VAL D CA  1 
ATOM   13887 C C   . VAL D 1 117 ? -32.800  -20.894 10.562  1.00 65.12  ? 177 VAL D C   1 
ATOM   13888 O O   . VAL D 1 117 ? -32.796  -19.809 9.901   1.00 61.20  ? 177 VAL D O   1 
ATOM   13889 C CB  . VAL D 1 117 ? -30.776  -22.414 10.279  1.00 48.01  ? 177 VAL D CB  1 
ATOM   13890 C CG1 . VAL D 1 117 ? -30.783  -22.036 8.804   1.00 46.12  ? 177 VAL D CG1 1 
ATOM   13891 C CG2 . VAL D 1 117 ? -29.367  -22.680 10.775  1.00 44.42  ? 177 VAL D CG2 1 
ATOM   13892 N N   . GLU D 1 118 ? -33.872  -21.682 10.782  1.00 69.26  ? 178 GLU D N   1 
ATOM   13893 C CA  . GLU D 1 118 ? -35.233  -21.454 10.213  1.00 70.16  ? 178 GLU D CA  1 
ATOM   13894 C C   . GLU D 1 118 ? -35.912  -20.272 10.923  1.00 67.87  ? 178 GLU D C   1 
ATOM   13895 O O   . GLU D 1 118 ? -36.587  -19.506 10.235  1.00 75.32  ? 178 GLU D O   1 
ATOM   13896 C CB  . GLU D 1 118 ? -36.088  -22.723 10.298  1.00 69.76  ? 178 GLU D CB  1 
ATOM   13897 C CG  . GLU D 1 118 ? -37.464  -22.553 9.674   1.00 77.06  ? 178 GLU D CG  1 
ATOM   13898 C CD  . GLU D 1 118 ? -38.215  -23.859 9.374   1.00 88.15  ? 178 GLU D CD  1 
ATOM   13899 O OE1 . GLU D 1 118 ? -37.634  -24.970 9.623   1.00 73.88  ? 178 GLU D OE1 1 
ATOM   13900 O OE2 . GLU D 1 118 ? -39.393  -23.775 8.892   1.00 79.45  ? 178 GLU D OE2 1 
ATOM   13901 N N   . LEU D 1 119 ? -35.700  -20.128 12.234  1.00 61.58  ? 179 LEU D N   1 
ATOM   13902 C CA  . LEU D 1 119 ? -36.478  -19.248 13.143  1.00 56.26  ? 179 LEU D CA  1 
ATOM   13903 C C   . LEU D 1 119 ? -35.760  -17.910 13.371  1.00 52.70  ? 179 LEU D C   1 
ATOM   13904 O O   . LEU D 1 119 ? -36.419  -16.958 13.794  1.00 58.36  ? 179 LEU D O   1 
ATOM   13905 C CB  . LEU D 1 119 ? -36.680  -19.986 14.479  1.00 54.99  ? 179 LEU D CB  1 
ATOM   13906 C CG  . LEU D 1 119 ? -38.015  -20.713 14.696  1.00 57.59  ? 179 LEU D CG  1 
ATOM   13907 C CD1 . LEU D 1 119 ? -38.521  -21.362 13.429  1.00 62.05  ? 179 LEU D CD1 1 
ATOM   13908 C CD2 . LEU D 1 119 ? -37.907  -21.760 15.787  1.00 62.08  ? 179 LEU D CD2 1 
ATOM   13909 N N   . LEU D 1 120 ? -34.449  -17.859 13.188  1.00 45.33  ? 180 LEU D N   1 
ATOM   13910 C CA  . LEU D 1 120 ? -33.637  -16.691 13.617  1.00 51.99  ? 180 LEU D CA  1 
ATOM   13911 C C   . LEU D 1 120 ? -34.080  -15.423 12.880  1.00 52.75  ? 180 LEU D C   1 
ATOM   13912 O O   . LEU D 1 120 ? -34.072  -14.317 13.452  1.00 39.90  ? 180 LEU D O   1 
ATOM   13913 C CB  . LEU D 1 120 ? -32.161  -17.000 13.362  1.00 59.98  ? 180 LEU D CB  1 
ATOM   13914 C CG  . LEU D 1 120 ? -31.163  -16.001 13.942  1.00 63.11  ? 180 LEU D CG  1 
ATOM   13915 C CD1 . LEU D 1 120 ? -31.401  -15.753 15.416  1.00 64.70  ? 180 LEU D CD1 1 
ATOM   13916 C CD2 . LEU D 1 120 ? -29.754  -16.472 13.733  1.00 65.26  ? 180 LEU D CD2 1 
ATOM   13917 N N   . PRO D 1 121 ? -34.464  -15.520 11.582  1.00 50.95  ? 181 PRO D N   1 
ATOM   13918 C CA  . PRO D 1 121 ? -34.859  -14.310 10.855  1.00 50.72  ? 181 PRO D CA  1 
ATOM   13919 C C   . PRO D 1 121 ? -36.194  -13.730 11.368  1.00 54.40  ? 181 PRO D C   1 
ATOM   13920 O O   . PRO D 1 121 ? -36.506  -12.590 11.033  1.00 59.33  ? 181 PRO D O   1 
ATOM   13921 C CB  . PRO D 1 121 ? -34.932  -14.768 9.381   1.00 47.67  ? 181 PRO D CB  1 
ATOM   13922 C CG  . PRO D 1 121 ? -34.302  -16.176 9.338   1.00 44.88  ? 181 PRO D CG  1 
ATOM   13923 C CD  . PRO D 1 121 ? -34.452  -16.738 10.737  1.00 45.33  ? 181 PRO D CD  1 
ATOM   13924 N N   . PHE D 1 122 ? -36.955  -14.510 12.150  1.00 54.13  ? 182 PHE D N   1 
ATOM   13925 C CA  . PHE D 1 122 ? -38.309  -14.148 12.654  1.00 53.09  ? 182 PHE D CA  1 
ATOM   13926 C C   . PHE D 1 122 ? -38.222  -13.485 14.041  1.00 53.25  ? 182 PHE D C   1 
ATOM   13927 O O   . PHE D 1 122 ? -38.899  -12.462 14.227  1.00 53.70  ? 182 PHE D O   1 
ATOM   13928 C CB  . PHE D 1 122 ? -39.210  -15.376 12.647  1.00 52.43  ? 182 PHE D CB  1 
ATOM   13929 C CG  . PHE D 1 122 ? -39.423  -15.960 11.275  1.00 56.38  ? 182 PHE D CG  1 
ATOM   13930 C CD1 . PHE D 1 122 ? -39.860  -15.160 10.231  1.00 52.22  ? 182 PHE D CD1 1 
ATOM   13931 C CD2 . PHE D 1 122 ? -39.222  -17.311 11.032  1.00 58.04  ? 182 PHE D CD2 1 
ATOM   13932 C CE1 . PHE D 1 122 ? -40.104  -15.706 8.981   1.00 52.84  ? 182 PHE D CE1 1 
ATOM   13933 C CE2 . PHE D 1 122 ? -39.441  -17.843 9.768   1.00 58.38  ? 182 PHE D CE2 1 
ATOM   13934 C CZ  . PHE D 1 122 ? -39.865  -17.037 8.744   1.00 54.28  ? 182 PHE D CZ  1 
ATOM   13935 N N   . VAL D 1 123 ? -37.388  -13.996 14.956  1.00 54.33  ? 183 VAL D N   1 
ATOM   13936 C CA  . VAL D 1 123 ? -37.181  -13.434 16.333  1.00 54.66  ? 183 VAL D CA  1 
ATOM   13937 C C   . VAL D 1 123 ? -36.121  -12.312 16.315  1.00 53.79  ? 183 VAL D C   1 
ATOM   13938 O O   . VAL D 1 123 ? -36.131  -11.485 17.228  1.00 45.46  ? 183 VAL D O   1 
ATOM   13939 C CB  . VAL D 1 123 ? -36.796  -14.561 17.317  1.00 55.39  ? 183 VAL D CB  1 
ATOM   13940 C CG1 . VAL D 1 123 ? -37.933  -15.546 17.456  1.00 57.15  ? 183 VAL D CG1 1 
ATOM   13941 C CG2 . VAL D 1 123 ? -35.521  -15.309 16.927  1.00 52.91  ? 183 VAL D CG2 1 
ATOM   13942 N N   . TYR D 1 124 ? -35.208  -12.340 15.334  1.00 61.39  ? 184 TYR D N   1 
ATOM   13943 C CA  . TYR D 1 124 ? -34.043  -11.427 15.149  1.00 57.71  ? 184 TYR D CA  1 
ATOM   13944 C C   . TYR D 1 124 ? -34.135  -10.773 13.769  1.00 47.78  ? 184 TYR D C   1 
ATOM   13945 O O   . TYR D 1 124 ? -35.190  -10.879 13.134  1.00 52.33  ? 184 TYR D O   1 
ATOM   13946 C CB  . TYR D 1 124 ? -32.719  -12.193 15.305  1.00 64.87  ? 184 TYR D CB  1 
ATOM   13947 C CG  . TYR D 1 124 ? -31.513  -11.347 15.649  1.00 59.54  ? 184 TYR D CG  1 
ATOM   13948 C CD1 . TYR D 1 124 ? -31.614  -10.219 16.455  1.00 59.70  ? 184 TYR D CD1 1 
ATOM   13949 C CD2 . TYR D 1 124 ? -30.268  -11.677 15.156  1.00 56.36  ? 184 TYR D CD2 1 
ATOM   13950 C CE1 . TYR D 1 124 ? -30.516  -9.437  16.759  1.00 59.81  ? 184 TYR D CE1 1 
ATOM   13951 C CE2 . TYR D 1 124 ? -29.165  -10.899 15.438  1.00 59.23  ? 184 TYR D CE2 1 
ATOM   13952 C CZ  . TYR D 1 124 ? -29.283  -9.781  16.246  1.00 64.84  ? 184 TYR D CZ  1 
ATOM   13953 O OH  . TYR D 1 124 ? -28.192  -9.007  16.517  1.00 72.65  ? 184 TYR D OH  1 
ATOM   13954 N N   . THR D 1 125 ? -33.081  -10.108 13.319  1.00 44.47  ? 185 THR D N   1 
ATOM   13955 C CA  . THR D 1 125 ? -33.044  -9.414  12.005  1.00 54.35  ? 185 THR D CA  1 
ATOM   13956 C C   . THR D 1 125 ? -33.357  -10.442 10.905  1.00 55.77  ? 185 THR D C   1 
ATOM   13957 O O   . THR D 1 125 ? -32.794  -11.549 10.897  1.00 49.70  ? 185 THR D O   1 
ATOM   13958 C CB  . THR D 1 125 ? -31.730  -8.644  11.776  1.00 52.71  ? 185 THR D CB  1 
ATOM   13959 O OG1 . THR D 1 125 ? -31.833  -7.878  10.570  1.00 50.06  ? 185 THR D OG1 1 
ATOM   13960 C CG2 . THR D 1 125 ? -30.540  -9.573  11.681  1.00 56.68  ? 185 THR D CG2 1 
ATOM   13961 N N   . PRO D 1 126 ? -34.248  -10.099 9.931   1.00 50.17  ? 186 PRO D N   1 
ATOM   13962 C CA  . PRO D 1 126 ? -34.844  -8.752  9.791   1.00 51.75  ? 186 PRO D CA  1 
ATOM   13963 C C   . PRO D 1 126 ? -36.234  -8.430  10.404  1.00 54.29  ? 186 PRO D C   1 
ATOM   13964 O O   . PRO D 1 126 ? -36.615  -7.245  10.519  1.00 49.47  ? 186 PRO D O   1 
ATOM   13965 C CB  . PRO D 1 126 ? -34.979  -8.699  8.274   1.00 48.31  ? 186 PRO D CB  1 
ATOM   13966 C CG  . PRO D 1 126 ? -35.431  -10.088 7.928   1.00 53.23  ? 186 PRO D CG  1 
ATOM   13967 C CD  . PRO D 1 126 ? -34.684  -11.005 8.869   1.00 49.26  ? 186 PRO D CD  1 
ATOM   13968 N N   . THR D 1 127 ? -36.979  -9.473  10.783  1.00 48.38  ? 187 THR D N   1 
ATOM   13969 C CA  . THR D 1 127 ? -38.373  -9.380  11.279  1.00 47.41  ? 187 THR D CA  1 
ATOM   13970 C C   . THR D 1 127 ? -38.459  -8.407  12.455  1.00 41.70  ? 187 THR D C   1 
ATOM   13971 O O   . THR D 1 127 ? -39.421  -7.617  12.527  1.00 36.34  ? 187 THR D O   1 
ATOM   13972 C CB  . THR D 1 127 ? -38.872  -10.762 11.692  1.00 44.93  ? 187 THR D CB  1 
ATOM   13973 O OG1 . THR D 1 127 ? -38.771  -11.610 10.548  1.00 49.50  ? 187 THR D OG1 1 
ATOM   13974 C CG2 . THR D 1 127 ? -40.292  -10.710 12.186  1.00 42.33  ? 187 THR D CG2 1 
ATOM   13975 N N   . VAL D 1 128 ? -37.494  -8.512  13.358  1.00 46.19  ? 188 VAL D N   1 
ATOM   13976 C CA  . VAL D 1 128 ? -37.469  -7.819  14.677  1.00 50.11  ? 188 VAL D CA  1 
ATOM   13977 C C   . VAL D 1 128 ? -37.491  -6.305  14.416  1.00 51.35  ? 188 VAL D C   1 
ATOM   13978 O O   . VAL D 1 128 ? -37.768  -5.532  15.352  1.00 49.29  ? 188 VAL D O   1 
ATOM   13979 C CB  . VAL D 1 128 ? -36.216  -8.269  15.463  1.00 52.58  ? 188 VAL D CB  1 
ATOM   13980 C CG1 . VAL D 1 128 ? -34.931  -7.712  14.853  1.00 51.82  ? 188 VAL D CG1 1 
ATOM   13981 C CG2 . VAL D 1 128 ? -36.310  -7.900  16.929  1.00 58.49  ? 188 VAL D CG2 1 
ATOM   13982 N N   . GLY D 1 129 ? -37.136  -5.901  13.194  1.00 51.79  ? 189 GLY D N   1 
ATOM   13983 C CA  . GLY D 1 129 ? -37.136  -4.491  12.784  1.00 50.83  ? 189 GLY D CA  1 
ATOM   13984 C C   . GLY D 1 129 ? -38.562  -4.019  12.601  1.00 51.23  ? 189 GLY D C   1 
ATOM   13985 O O   . GLY D 1 129 ? -38.911  -2.998  13.166  1.00 49.15  ? 189 GLY D O   1 
ATOM   13986 N N   . GLU D 1 130 ? -39.340  -4.741  11.788  1.00 57.04  ? 190 GLU D N   1 
ATOM   13987 C CA  . GLU D 1 130 ? -40.777  -4.482  11.547  1.00 54.46  ? 190 GLU D CA  1 
ATOM   13988 C C   . GLU D 1 130 ? -41.504  -4.487  12.904  1.00 63.85  ? 190 GLU D C   1 
ATOM   13989 O O   . GLU D 1 130 ? -42.291  -3.537  13.188  1.00 52.59  ? 190 GLU D O   1 
ATOM   13990 C CB  . GLU D 1 130 ? -41.322  -5.538  10.583  1.00 55.53  ? 190 GLU D CB  1 
ATOM   13991 C CG  . GLU D 1 130 ? -42.824  -5.423  10.394  1.00 58.62  ? 190 GLU D CG  1 
ATOM   13992 C CD  . GLU D 1 130 ? -43.464  -6.240  9.291   1.00 58.88  ? 190 GLU D CD  1 
ATOM   13993 O OE1 . GLU D 1 130 ? -43.226  -7.479  9.209   1.00 69.34  ? 190 GLU D OE1 1 
ATOM   13994 O OE2 . GLU D 1 130 ? -44.234  -5.631  8.541   1.00 62.41  ? 190 GLU D OE2 1 
ATOM   13995 N N   . ALA D 1 131 ? -41.232  -5.503  13.736  1.00 65.49  ? 191 ALA D N   1 
ATOM   13996 C CA  . ALA D 1 131 ? -41.834  -5.634  15.081  1.00 59.35  ? 191 ALA D CA  1 
ATOM   13997 C C   . ALA D 1 131 ? -41.647  -4.302  15.806  1.00 52.70  ? 191 ALA D C   1 
ATOM   13998 O O   . ALA D 1 131 ? -42.587  -3.850  16.407  1.00 60.06  ? 191 ALA D O   1 
ATOM   13999 C CB  . ALA D 1 131 ? -41.257  -6.800  15.859  1.00 55.46  ? 191 ALA D CB  1 
ATOM   14000 N N   . CYS D 1 132 ? -40.478  -3.677  15.721  1.00 53.49  ? 192 CYS D N   1 
ATOM   14001 C CA  . CYS D 1 132 ? -40.182  -2.403  16.441  1.00 54.21  ? 192 CYS D CA  1 
ATOM   14002 C C   . CYS D 1 132 ? -40.948  -1.232  15.812  1.00 47.17  ? 192 CYS D C   1 
ATOM   14003 O O   . CYS D 1 132 ? -41.310  -0.305  16.527  1.00 53.24  ? 192 CYS D O   1 
ATOM   14004 C CB  . CYS D 1 132 ? -38.694  -2.077  16.472  1.00 51.55  ? 192 CYS D CB  1 
ATOM   14005 S SG  . CYS D 1 132 ? -37.794  -3.085  17.666  1.00 60.94  ? 192 CYS D SG  1 
ATOM   14006 N N   . GLN D 1 133 ? -41.167  -1.258  14.514  1.00 47.70  ? 193 GLN D N   1 
ATOM   14007 C CA  . GLN D 1 133 ? -41.828  -0.139  13.804  1.00 50.06  ? 193 GLN D CA  1 
ATOM   14008 C C   . GLN D 1 133 ? -43.317  -0.149  14.159  1.00 47.58  ? 193 GLN D C   1 
ATOM   14009 O O   . GLN D 1 133 ? -43.918  0.943   14.182  1.00 46.07  ? 193 GLN D O   1 
ATOM   14010 C CB  . GLN D 1 133 ? -41.617  -0.280  12.298  1.00 50.94  ? 193 GLN D CB  1 
ATOM   14011 C CG  . GLN D 1 133 ? -40.247  0.154   11.849  1.00 50.71  ? 193 GLN D CG  1 
ATOM   14012 C CD  . GLN D 1 133 ? -40.065  -0.151  10.380  1.00 55.21  ? 193 GLN D CD  1 
ATOM   14013 O OE1 . GLN D 1 133 ? -40.206  -1.290  9.945   1.00 49.26  ? 193 GLN D OE1 1 
ATOM   14014 N NE2 . GLN D 1 133 ? -39.719  0.865   9.596   1.00 67.89  ? 193 GLN D NE2 1 
ATOM   14015 N N   . LYS D 1 134 ? -43.865  -1.342  14.408  1.00 46.85  ? 194 LYS D N   1 
ATOM   14016 C CA  . LYS D 1 134 ? -45.308  -1.578  14.662  1.00 49.52  ? 194 LYS D CA  1 
ATOM   14017 C C   . LYS D 1 134 ? -45.517  -2.090  16.092  1.00 46.63  ? 194 LYS D C   1 
ATOM   14018 O O   . LYS D 1 134 ? -46.529  -2.729  16.313  1.00 57.40  ? 194 LYS D O   1 
ATOM   14019 C CB  . LYS D 1 134 ? -45.873  -2.610  13.672  1.00 56.50  ? 194 LYS D CB  1 
ATOM   14020 C CG  . LYS D 1 134 ? -45.777  -2.243  12.195  1.00 62.75  ? 194 LYS D CG  1 
ATOM   14021 C CD  . LYS D 1 134 ? -46.562  -3.213  11.310  1.00 69.36  ? 194 LYS D CD  1 
ATOM   14022 C CE  . LYS D 1 134 ? -46.080  -3.326  9.873   1.00 67.10  ? 194 LYS D CE  1 
ATOM   14023 N NZ  . LYS D 1 134 ? -45.901  -1.990  9.272   1.00 69.68  ? 194 LYS D NZ  1 
ATOM   14024 N N   . TYR D 1 135 ? -44.614  -1.821  17.029  1.00 48.26  ? 195 TYR D N   1 
ATOM   14025 C CA  . TYR D 1 135 ? -44.602  -2.435  18.381  1.00 46.54  ? 195 TYR D CA  1 
ATOM   14026 C C   . TYR D 1 135 ? -45.897  -2.081  19.096  1.00 49.60  ? 195 TYR D C   1 
ATOM   14027 O O   . TYR D 1 135 ? -46.525  -2.993  19.699  1.00 52.11  ? 195 TYR D O   1 
ATOM   14028 C CB  . TYR D 1 135 ? -43.403  -1.966  19.203  1.00 48.10  ? 195 TYR D CB  1 
ATOM   14029 C CG  . TYR D 1 135 ? -42.880  -2.984  20.192  1.00 58.97  ? 195 TYR D CG  1 
ATOM   14030 C CD1 . TYR D 1 135 ? -42.368  -4.214  19.761  1.00 60.61  ? 195 TYR D CD1 1 
ATOM   14031 C CD2 . TYR D 1 135 ? -42.863  -2.716  21.554  1.00 51.52  ? 195 TYR D CD2 1 
ATOM   14032 C CE1 . TYR D 1 135 ? -41.859  -5.143  20.651  1.00 48.23  ? 195 TYR D CE1 1 
ATOM   14033 C CE2 . TYR D 1 135 ? -42.376  -3.646  22.456  1.00 47.59  ? 195 TYR D CE2 1 
ATOM   14034 C CZ  . TYR D 1 135 ? -41.863  -4.848  22.000  1.00 46.21  ? 195 TYR D CZ  1 
ATOM   14035 O OH  . TYR D 1 135 ? -41.366  -5.755  22.883  1.00 50.08  ? 195 TYR D OH  1 
ATOM   14036 N N   . GLY D 1 136 ? -46.290  -0.809  19.006  1.00 53.03  ? 196 GLY D N   1 
ATOM   14037 C CA  . GLY D 1 136 ? -47.466  -0.261  19.704  1.00 59.41  ? 196 GLY D CA  1 
ATOM   14038 C C   . GLY D 1 136 ? -48.756  -0.961  19.302  1.00 55.57  ? 196 GLY D C   1 
ATOM   14039 O O   . GLY D 1 136 ? -49.611  -1.127  20.154  1.00 62.04  ? 196 GLY D O   1 
ATOM   14040 N N   . SER D 1 137 ? -48.883  -1.341  18.037  1.00 51.83  ? 197 SER D N   1 
ATOM   14041 C CA  . SER D 1 137 ? -50.120  -1.878  17.438  1.00 56.22  ? 197 SER D CA  1 
ATOM   14042 C C   . SER D 1 137 ? -50.153  -3.415  17.518  1.00 53.41  ? 197 SER D C   1 
ATOM   14043 O O   . SER D 1 137 ? -51.203  -3.975  17.165  1.00 61.17  ? 197 SER D O   1 
ATOM   14044 C CB  . SER D 1 137 ? -50.256  -1.357  16.034  1.00 56.03  ? 197 SER D CB  1 
ATOM   14045 O OG  . SER D 1 137 ? -49.344  -2.029  15.188  1.00 59.86  ? 197 SER D OG  1 
ATOM   14046 N N   . ILE D 1 138 ? -49.088  -4.056  17.996  1.00 58.31  ? 198 ILE D N   1 
ATOM   14047 C CA  . ILE D 1 138 ? -48.992  -5.537  18.139  1.00 73.25  ? 198 ILE D CA  1 
ATOM   14048 C C   . ILE D 1 138 ? -49.609  -5.953  19.478  1.00 79.91  ? 198 ILE D C   1 
ATOM   14049 O O   . ILE D 1 138 ? -49.402  -5.208  20.475  1.00 69.33  ? 198 ILE D O   1 
ATOM   14050 C CB  . ILE D 1 138 ? -47.550  -6.087  18.075  1.00 84.55  ? 198 ILE D CB  1 
ATOM   14051 C CG1 . ILE D 1 138 ? -46.749  -5.665  16.857  1.00 87.27  ? 198 ILE D CG1 1 
ATOM   14052 C CG2 . ILE D 1 138 ? -47.599  -7.602  18.131  1.00 101.99 ? 198 ILE D CG2 1 
ATOM   14053 C CD1 . ILE D 1 138 ? -47.304  -6.249  15.599  1.00 91.48  ? 198 ILE D CD1 1 
ATOM   14054 N N   . PHE D 1 139 ? -50.323  -7.097  19.484  1.00 107.73 ? 199 PHE D N   1 
ATOM   14055 C CA  . PHE D 1 139 ? -50.825  -7.821  20.680  1.00 125.70 ? 199 PHE D CA  1 
ATOM   14056 C C   . PHE D 1 139 ? -49.640  -8.040  21.626  1.00 122.16 ? 199 PHE D C   1 
ATOM   14057 O O   . PHE D 1 139 ? -48.633  -8.692  21.242  1.00 108.47 ? 199 PHE D O   1 
ATOM   14058 C CB  . PHE D 1 139 ? -51.516  -9.142  20.299  1.00 127.19 ? 199 PHE D CB  1 
ATOM   14059 C CG  . PHE D 1 139 ? -51.777  -10.085 21.453  1.00 125.54 ? 199 PHE D CG  1 
ATOM   14060 C CD1 . PHE D 1 139 ? -52.920  -9.975  22.236  1.00 115.98 ? 199 PHE D CD1 1 
ATOM   14061 C CD2 . PHE D 1 139 ? -50.831  -11.042 21.798  1.00 119.06 ? 199 PHE D CD2 1 
ATOM   14062 C CE1 . PHE D 1 139 ? -53.128  -10.834 23.305  1.00 111.06 ? 199 PHE D CE1 1 
ATOM   14063 C CE2 . PHE D 1 139 ? -51.027  -11.877 22.887  1.00 111.74 ? 199 PHE D CE2 1 
ATOM   14064 C CZ  . PHE D 1 139 ? -52.178  -11.777 23.632  1.00 109.09 ? 199 PHE D CZ  1 
ATOM   14065 N N   . ARG D 1 140 ? -49.796  -7.517  22.848  1.00 113.54 ? 200 ARG D N   1 
ATOM   14066 C CA  . ARG D 1 140 ? -48.706  -7.272  23.813  1.00 107.26 ? 200 ARG D CA  1 
ATOM   14067 C C   . ARG D 1 140 ? -48.889  -8.177  25.041  1.00 103.31 ? 200 ARG D C   1 
ATOM   14068 O O   . ARG D 1 140 ? -49.730  -7.881  25.880  1.00 98.13  ? 200 ARG D O   1 
ATOM   14069 C CB  . ARG D 1 140 ? -48.684  -5.777  24.148  1.00 101.54 ? 200 ARG D CB  1 
ATOM   14070 C CG  . ARG D 1 140 ? -50.024  -5.191  24.580  1.00 96.38  ? 200 ARG D CG  1 
ATOM   14071 C CD  . ARG D 1 140 ? -50.992  -4.825  23.468  1.00 90.60  ? 200 ARG D CD  1 
ATOM   14072 N NE  . ARG D 1 140 ? -52.046  -3.820  23.694  1.00 89.11  ? 200 ARG D NE  1 
ATOM   14073 C CZ  . ARG D 1 140 ? -52.844  -3.677  24.757  1.00 63.36  ? 200 ARG D CZ  1 
ATOM   14074 N NH1 . ARG D 1 140 ? -52.737  -4.431  25.830  1.00 52.77  ? 200 ARG D NH1 1 
ATOM   14075 N NH2 . ARG D 1 140 ? -53.722  -2.704  24.754  1.00 65.34  ? 200 ARG D NH2 1 
ATOM   14076 N N   . ARG D 1 141 ? -48.149  -9.284  25.103  1.00 101.00 ? 201 ARG D N   1 
ATOM   14077 C CA  . ARG D 1 141 ? -47.765  -9.939  26.376  1.00 101.31 ? 201 ARG D CA  1 
ATOM   14078 C C   . ARG D 1 141 ? -46.575  -9.110  26.878  1.00 99.17  ? 201 ARG D C   1 
ATOM   14079 O O   . ARG D 1 141 ? -45.641  -8.887  26.111  1.00 110.38 ? 201 ARG D O   1 
ATOM   14080 C CB  . ARG D 1 141 ? -47.513  -11.438 26.138  1.00 98.95  ? 201 ARG D CB  1 
ATOM   14081 C CG  . ARG D 1 141 ? -48.717  -12.357 26.361  1.00 102.89 ? 201 ARG D CG  1 
ATOM   14082 C CD  . ARG D 1 141 ? -49.012  -12.695 27.828  1.00 118.31 ? 201 ARG D CD  1 
ATOM   14083 N NE  . ARG D 1 141 ? -47.796  -12.698 28.650  1.00 134.14 ? 201 ARG D NE  1 
ATOM   14084 C CZ  . ARG D 1 141 ? -47.696  -12.346 29.938  1.00 127.01 ? 201 ARG D CZ  1 
ATOM   14085 N NH1 . ARG D 1 141 ? -46.510  -12.342 30.528  1.00 115.13 ? 201 ARG D NH1 1 
ATOM   14086 N NH2 . ARG D 1 141 ? -48.758  -11.962 30.625  1.00 124.96 ? 201 ARG D NH2 1 
ATOM   14087 N N   . PRO D 1 142 ? -46.571  -8.557  28.121  1.00 92.04  ? 202 PRO D N   1 
ATOM   14088 C CA  . PRO D 1 142 ? -45.484  -7.658  28.543  1.00 76.11  ? 202 PRO D CA  1 
ATOM   14089 C C   . PRO D 1 142 ? -44.098  -8.349  28.667  1.00 73.14  ? 202 PRO D C   1 
ATOM   14090 O O   . PRO D 1 142 ? -43.968  -9.512  29.095  1.00 62.51  ? 202 PRO D O   1 
ATOM   14091 C CB  . PRO D 1 142 ? -45.976  -7.050  29.862  1.00 68.46  ? 202 PRO D CB  1 
ATOM   14092 C CG  . PRO D 1 142 ? -47.047  -8.015  30.371  1.00 82.73  ? 202 PRO D CG  1 
ATOM   14093 C CD  . PRO D 1 142 ? -47.566  -8.807  29.182  1.00 92.49  ? 202 PRO D CD  1 
ATOM   14094 N N   . GLN D 1 143 ? -43.065  -7.625  28.241  1.00 67.24  ? 203 GLN D N   1 
ATOM   14095 C CA  . GLN D 1 143 ? -41.651  -8.081  28.185  1.00 62.05  ? 203 GLN D CA  1 
ATOM   14096 C C   . GLN D 1 143 ? -40.724  -6.895  28.487  1.00 60.33  ? 203 GLN D C   1 
ATOM   14097 O O   . GLN D 1 143 ? -41.009  -5.746  28.002  1.00 45.95  ? 203 GLN D O   1 
ATOM   14098 C CB  . GLN D 1 143 ? -41.350  -8.654  26.796  1.00 58.33  ? 203 GLN D CB  1 
ATOM   14099 C CG  . GLN D 1 143 ? -41.858  -10.070 26.621  1.00 54.23  ? 203 GLN D CG  1 
ATOM   14100 C CD  . GLN D 1 143 ? -41.654  -10.566 25.222  1.00 53.42  ? 203 GLN D CD  1 
ATOM   14101 O OE1 . GLN D 1 143 ? -41.854  -9.795  24.280  1.00 53.48  ? 203 GLN D OE1 1 
ATOM   14102 N NE2 . GLN D 1 143 ? -41.258  -11.837 25.108  1.00 52.54  ? 203 GLN D NE2 1 
ATOM   14103 N N   . GLY D 1 144 ? -39.681  -7.162  29.283  1.00 52.70  ? 204 GLY D N   1 
ATOM   14104 C CA  . GLY D 1 144 ? -38.664  -6.172  29.676  1.00 53.78  ? 204 GLY D CA  1 
ATOM   14105 C C   . GLY D 1 144 ? -39.198  -5.063  30.581  1.00 48.31  ? 204 GLY D C   1 
ATOM   14106 O O   . GLY D 1 144 ? -40.397  -5.052  30.950  1.00 56.46  ? 204 GLY D O   1 
ATOM   14107 N N   . LEU D 1 145 ? -38.330  -4.131  30.915  1.00 38.61  ? 205 LEU D N   1 
ATOM   14108 C CA  . LEU D 1 145 ? -38.630  -3.053  31.868  1.00 45.51  ? 205 LEU D CA  1 
ATOM   14109 C C   . LEU D 1 145 ? -38.439  -1.694  31.182  1.00 45.32  ? 205 LEU D C   1 
ATOM   14110 O O   . LEU D 1 145 ? -37.411  -1.520  30.502  1.00 42.45  ? 205 LEU D O   1 
ATOM   14111 C CB  . LEU D 1 145 ? -37.674  -3.258  33.042  1.00 48.95  ? 205 LEU D CB  1 
ATOM   14112 C CG  . LEU D 1 145 ? -37.961  -2.471  34.304  1.00 52.83  ? 205 LEU D CG  1 
ATOM   14113 C CD1 . LEU D 1 145 ? -37.820  -3.352  35.533  1.00 58.10  ? 205 LEU D CD1 1 
ATOM   14114 C CD2 . LEU D 1 145 ? -37.023  -1.274  34.368  1.00 53.80  ? 205 LEU D CD2 1 
ATOM   14115 N N   . TYR D 1 146 ? -39.385  -0.768  31.345  1.00 37.67  ? 206 TYR D N   1 
ATOM   14116 C CA  . TYR D 1 146 ? -39.295  0.581   30.743  1.00 39.26  ? 206 TYR D CA  1 
ATOM   14117 C C   . TYR D 1 146 ? -39.031  1.604   31.847  1.00 37.78  ? 206 TYR D C   1 
ATOM   14118 O O   . TYR D 1 146 ? -39.873  1.763   32.768  1.00 37.91  ? 206 TYR D O   1 
ATOM   14119 C CB  . TYR D 1 146 ? -40.579  0.927   29.987  1.00 44.89  ? 206 TYR D CB  1 
ATOM   14120 C CG  . TYR D 1 146 ? -41.010  -0.059  28.928  1.00 47.63  ? 206 TYR D CG  1 
ATOM   14121 C CD1 . TYR D 1 146 ? -41.503  -1.308  29.306  1.00 52.78  ? 206 TYR D CD1 1 
ATOM   14122 C CD2 . TYR D 1 146 ? -40.952  0.240   27.576  1.00 40.30  ? 206 TYR D CD2 1 
ATOM   14123 C CE1 . TYR D 1 146 ? -41.922  -2.246  28.382  1.00 44.83  ? 206 TYR D CE1 1 
ATOM   14124 C CE2 . TYR D 1 146 ? -41.378  -0.681  26.638  1.00 46.53  ? 206 TYR D CE2 1 
ATOM   14125 C CZ  . TYR D 1 146 ? -41.871  -1.922  27.046  1.00 48.42  ? 206 TYR D CZ  1 
ATOM   14126 O OH  . TYR D 1 146 ? -42.293  -2.900  26.192  1.00 59.28  ? 206 TYR D OH  1 
ATOM   14127 N N   . VAL D 1 147 ? -37.911  2.303   31.753  1.00 36.78  ? 207 VAL D N   1 
ATOM   14128 C CA  . VAL D 1 147 ? -37.591  3.465   32.640  1.00 40.36  ? 207 VAL D CA  1 
ATOM   14129 C C   . VAL D 1 147 ? -37.810  4.773   31.877  1.00 39.53  ? 207 VAL D C   1 
ATOM   14130 O O   . VAL D 1 147 ? -37.041  5.059   30.931  1.00 44.67  ? 207 VAL D O   1 
ATOM   14131 C CB  . VAL D 1 147 ? -36.141  3.375   33.122  1.00 42.70  ? 207 VAL D CB  1 
ATOM   14132 C CG1 . VAL D 1 147 ? -35.725  4.602   33.935  1.00 42.58  ? 207 VAL D CG1 1 
ATOM   14133 C CG2 . VAL D 1 147 ? -35.906  2.060   33.859  1.00 44.57  ? 207 VAL D CG2 1 
ATOM   14134 N N   . SER D 1 148 ? -38.822  5.541   32.235  1.00 42.15  ? 208 SER D N   1 
ATOM   14135 C CA  . SER D 1 148 ? -39.125  6.817   31.532  1.00 54.37  ? 208 SER D CA  1 
ATOM   14136 C C   . SER D 1 148 ? -38.407  7.976   32.215  1.00 49.36  ? 208 SER D C   1 
ATOM   14137 O O   . SER D 1 148 ? -37.820  7.771   33.260  1.00 45.77  ? 208 SER D O   1 
ATOM   14138 C CB  . SER D 1 148 ? -40.606  7.092   31.435  1.00 58.83  ? 208 SER D CB  1 
ATOM   14139 O OG  . SER D 1 148 ? -41.132  7.486   32.693  1.00 70.84  ? 208 SER D OG  1 
ATOM   14140 N N   . LEU D 1 149 ? -38.462  9.139   31.584  1.00 58.78  ? 209 LEU D N   1 
ATOM   14141 C CA  . LEU D 1 149 ? -38.035  10.457  32.127  1.00 65.84  ? 209 LEU D CA  1 
ATOM   14142 C C   . LEU D 1 149 ? -38.797  10.753  33.416  1.00 69.17  ? 209 LEU D C   1 
ATOM   14143 O O   . LEU D 1 149 ? -38.309  11.540  34.225  1.00 76.18  ? 209 LEU D O   1 
ATOM   14144 C CB  . LEU D 1 149 ? -38.372  11.549  31.109  1.00 60.58  ? 209 LEU D CB  1 
ATOM   14145 C CG  . LEU D 1 149 ? -37.192  12.100  30.334  1.00 59.99  ? 209 LEU D CG  1 
ATOM   14146 C CD1 . LEU D 1 149 ? -37.702  12.913  29.153  1.00 66.59  ? 209 LEU D CD1 1 
ATOM   14147 C CD2 . LEU D 1 149 ? -36.289  12.928  31.236  1.00 57.98  ? 209 LEU D CD2 1 
ATOM   14148 N N   . LYS D 1 150 ? -39.997  10.199  33.558  1.00 79.62  ? 210 LYS D N   1 
ATOM   14149 C CA  . LYS D 1 150 ? -40.844  10.521  34.727  1.00 91.62  ? 210 LYS D CA  1 
ATOM   14150 C C   . LYS D 1 150 ? -40.642  9.472   35.818  1.00 76.41  ? 210 LYS D C   1 
ATOM   14151 O O   . LYS D 1 150 ? -41.429  9.479   36.757  1.00 69.23  ? 210 LYS D O   1 
ATOM   14152 C CB  . LYS D 1 150 ? -42.268  10.811  34.247  1.00 102.63 ? 210 LYS D CB  1 
ATOM   14153 C CG  . LYS D 1 150 ? -42.331  12.167  33.518  1.00 119.87 ? 210 LYS D CG  1 
ATOM   14154 C CD  . LYS D 1 150 ? -42.621  13.439  34.372  1.00 120.71 ? 210 LYS D CD  1 
ATOM   14155 C CE  . LYS D 1 150 ? -41.714  13.723  35.567  1.00 119.28 ? 210 LYS D CE  1 
ATOM   14156 N NZ  . LYS D 1 150 ? -40.404  14.303  35.173  1.00 119.45 ? 210 LYS D NZ  1 
ATOM   14157 N N   . ASP D 1 151 ? -39.580  8.671   35.720  1.00 65.35  ? 211 ASP D N   1 
ATOM   14158 C CA  . ASP D 1 151 ? -39.152  7.708   36.767  1.00 67.05  ? 211 ASP D CA  1 
ATOM   14159 C C   . ASP D 1 151 ? -37.875  8.261   37.425  1.00 59.84  ? 211 ASP D C   1 
ATOM   14160 O O   . ASP D 1 151 ? -37.251  7.539   38.257  1.00 62.63  ? 211 ASP D O   1 
ATOM   14161 C CB  . ASP D 1 151 ? -39.042  6.288   36.183  1.00 64.40  ? 211 ASP D CB  1 
ATOM   14162 C CG  . ASP D 1 151 ? -40.330  5.755   35.567  1.00 60.31  ? 211 ASP D CG  1 
ATOM   14163 O OD1 . ASP D 1 151 ? -41.381  5.970   36.173  1.00 57.57  ? 211 ASP D OD1 1 
ATOM   14164 O OD2 . ASP D 1 151 ? -40.274  5.128   34.481  1.00 64.87  ? 211 ASP D OD2 1 
ATOM   14165 N N   . LYS D 1 152 ? -37.501  9.508   37.121  1.00 57.43  ? 212 LYS D N   1 
ATOM   14166 C CA  . LYS D 1 152 ? -36.237  10.081  37.672  1.00 66.13  ? 212 LYS D CA  1 
ATOM   14167 C C   . LYS D 1 152 ? -36.501  10.510  39.116  1.00 56.04  ? 212 LYS D C   1 
ATOM   14168 O O   . LYS D 1 152 ? -37.596  10.936  39.413  1.00 57.39  ? 212 LYS D O   1 
ATOM   14169 C CB  . LYS D 1 152 ? -35.619  11.168  36.783  1.00 72.64  ? 212 LYS D CB  1 
ATOM   14170 C CG  . LYS D 1 152 ? -35.784  12.622  37.201  1.00 78.53  ? 212 LYS D CG  1 
ATOM   14171 C CD  . LYS D 1 152 ? -34.440  13.380  37.216  1.00 92.75  ? 212 LYS D CD  1 
ATOM   14172 C CE  . LYS D 1 152 ? -33.613  13.015  38.443  1.00 86.14  ? 212 LYS D CE  1 
ATOM   14173 N NZ  . LYS D 1 152 ? -32.174  12.830  38.138  1.00 75.15  ? 212 LYS D NZ  1 
ATOM   14174 N N   . GLY D 1 153 ? -35.529  10.322  39.989  1.00 55.52  ? 213 GLY D N   1 
ATOM   14175 C CA  . GLY D 1 153 ? -35.730  10.277  41.445  1.00 59.18  ? 213 GLY D CA  1 
ATOM   14176 C C   . GLY D 1 153 ? -36.093  8.878   41.913  1.00 65.05  ? 213 GLY D C   1 
ATOM   14177 O O   . GLY D 1 153 ? -35.750  8.557   43.050  1.00 76.83  ? 213 GLY D O   1 
ATOM   14178 N N   . LYS D 1 154 ? -36.745  8.059   41.080  1.00 64.93  ? 214 LYS D N   1 
ATOM   14179 C CA  . LYS D 1 154 ? -37.382  6.790   41.534  1.00 70.06  ? 214 LYS D CA  1 
ATOM   14180 C C   . LYS D 1 154 ? -36.947  5.616   40.646  1.00 63.55  ? 214 LYS D C   1 
ATOM   14181 O O   . LYS D 1 154 ? -37.661  4.615   40.596  1.00 59.65  ? 214 LYS D O   1 
ATOM   14182 C CB  . LYS D 1 154 ? -38.907  6.910   41.544  1.00 77.81  ? 214 LYS D CB  1 
ATOM   14183 C CG  . LYS D 1 154 ? -39.475  8.276   41.959  1.00 86.44  ? 214 LYS D CG  1 
ATOM   14184 C CD  . LYS D 1 154 ? -40.978  8.412   41.740  1.00 89.79  ? 214 LYS D CD  1 
ATOM   14185 C CE  . LYS D 1 154 ? -41.437  9.739   41.143  1.00 83.51  ? 214 LYS D CE  1 
ATOM   14186 N NZ  . LYS D 1 154 ? -42.911  9.879   41.197  1.00 73.75  ? 214 LYS D NZ  1 
ATOM   14187 N N   . VAL D 1 155 ? -35.812  5.727   39.969  1.00 60.39  ? 215 VAL D N   1 
ATOM   14188 C CA  . VAL D 1 155 ? -35.336  4.657   39.050  1.00 61.82  ? 215 VAL D CA  1 
ATOM   14189 C C   . VAL D 1 155 ? -35.135  3.365   39.842  1.00 57.42  ? 215 VAL D C   1 
ATOM   14190 O O   . VAL D 1 155 ? -35.426  2.301   39.305  1.00 52.23  ? 215 VAL D O   1 
ATOM   14191 C CB  . VAL D 1 155 ? -34.040  5.076   38.341  1.00 61.67  ? 215 VAL D CB  1 
ATOM   14192 C CG1 . VAL D 1 155 ? -33.377  3.900   37.648  1.00 61.11  ? 215 VAL D CG1 1 
ATOM   14193 C CG2 . VAL D 1 155 ? -34.299  6.226   37.377  1.00 57.49  ? 215 VAL D CG2 1 
ATOM   14194 N N   . LEU D 1 156 ? -34.616  3.461   41.060  1.00 58.43  ? 216 LEU D N   1 
ATOM   14195 C CA  . LEU D 1 156 ? -34.367  2.275   41.906  1.00 63.73  ? 216 LEU D CA  1 
ATOM   14196 C C   . LEU D 1 156 ? -35.688  1.584   42.197  1.00 63.48  ? 216 LEU D C   1 
ATOM   14197 O O   . LEU D 1 156 ? -35.695  0.343   42.179  1.00 50.48  ? 216 LEU D O   1 
ATOM   14198 C CB  . LEU D 1 156 ? -33.729  2.723   43.218  1.00 74.27  ? 216 LEU D CB  1 
ATOM   14199 C CG  . LEU D 1 156 ? -32.282  3.149   43.111  1.00 78.31  ? 216 LEU D CG  1 
ATOM   14200 C CD1 . LEU D 1 156 ? -32.023  4.280   44.098  1.00 84.29  ? 216 LEU D CD1 1 
ATOM   14201 C CD2 . LEU D 1 156 ? -31.371  1.938   43.325  1.00 71.88  ? 216 LEU D CD2 1 
ATOM   14202 N N   . GLU D 1 157 ? -36.723  2.388   42.510  1.00 81.09  ? 217 GLU D N   1 
ATOM   14203 C CA  . GLU D 1 157 ? -38.116  1.934   42.768  1.00 74.02  ? 217 GLU D CA  1 
ATOM   14204 C C   . GLU D 1 157 ? -38.566  1.064   41.590  1.00 72.42  ? 217 GLU D C   1 
ATOM   14205 O O   . GLU D 1 157 ? -39.189  0.020   41.831  1.00 78.76  ? 217 GLU D O   1 
ATOM   14206 C CB  . GLU D 1 157 ? -39.090  3.110   42.904  1.00 79.63  ? 217 GLU D CB  1 
ATOM   14207 C CG  . GLU D 1 157 ? -39.141  3.792   44.260  1.00 93.91  ? 217 GLU D CG  1 
ATOM   14208 C CD  . GLU D 1 157 ? -40.456  4.546   44.507  1.00 102.63 ? 217 GLU D CD  1 
ATOM   14209 O OE1 . GLU D 1 157 ? -41.538  4.013   44.148  1.00 96.89  ? 217 GLU D OE1 1 
ATOM   14210 O OE2 . GLU D 1 157 ? -40.413  5.693   45.021  1.00 110.28 ? 217 GLU D OE2 1 
ATOM   14211 N N   . VAL D 1 158 ? -38.253  1.484   40.358  1.00 61.77  ? 218 VAL D N   1 
ATOM   14212 C CA  . VAL D 1 158 ? -38.653  0.777   39.107  1.00 52.94  ? 218 VAL D CA  1 
ATOM   14213 C C   . VAL D 1 158 ? -37.875  -0.542  39.036  1.00 48.86  ? 218 VAL D C   1 
ATOM   14214 O O   . VAL D 1 158 ? -38.465  -1.584  38.767  1.00 46.85  ? 218 VAL D O   1 
ATOM   14215 C CB  . VAL D 1 158 ? -38.442  1.654   37.856  1.00 52.14  ? 218 VAL D CB  1 
ATOM   14216 C CG1 . VAL D 1 158 ? -38.888  0.940   36.591  1.00 49.46  ? 218 VAL D CG1 1 
ATOM   14217 C CG2 . VAL D 1 158 ? -39.150  3.007   37.940  1.00 55.28  ? 218 VAL D CG2 1 
ATOM   14218 N N   . LEU D 1 159 ? -36.579  -0.509  39.299  1.00 55.52  ? 219 LEU D N   1 
ATOM   14219 C CA  . LEU D 1 159 ? -35.730  -1.728  39.219  1.00 58.10  ? 219 LEU D CA  1 
ATOM   14220 C C   . LEU D 1 159 ? -36.309  -2.777  40.177  1.00 52.86  ? 219 LEU D C   1 
ATOM   14221 O O   . LEU D 1 159 ? -36.366  -3.991  39.851  1.00 41.34  ? 219 LEU D O   1 
ATOM   14222 C CB  . LEU D 1 159 ? -34.279  -1.337  39.534  1.00 61.61  ? 219 LEU D CB  1 
ATOM   14223 C CG  . LEU D 1 159 ? -33.553  -0.546  38.435  1.00 57.18  ? 219 LEU D CG  1 
ATOM   14224 C CD1 . LEU D 1 159 ? -32.110  -0.288  38.811  1.00 56.89  ? 219 LEU D CD1 1 
ATOM   14225 C CD2 . LEU D 1 159 ? -33.584  -1.286  37.107  1.00 57.74  ? 219 LEU D CD2 1 
ATOM   14226 N N   . ARG D 1 160 ? -36.784  -2.292  41.320  1.00 54.72  ? 220 ARG D N   1 
ATOM   14227 C CA  . ARG D 1 160 ? -37.172  -3.132  42.473  1.00 60.38  ? 220 ARG D CA  1 
ATOM   14228 C C   . ARG D 1 160 ? -38.338  -4.018  42.038  1.00 55.53  ? 220 ARG D C   1 
ATOM   14229 O O   . ARG D 1 160 ? -38.458  -5.129  42.579  1.00 55.41  ? 220 ARG D O   1 
ATOM   14230 C CB  . ARG D 1 160 ? -37.455  -2.164  43.628  1.00 66.88  ? 220 ARG D CB  1 
ATOM   14231 C CG  . ARG D 1 160 ? -38.090  -2.730  44.884  1.00 79.66  ? 220 ARG D CG  1 
ATOM   14232 C CD  . ARG D 1 160 ? -39.423  -2.063  45.197  1.00 86.56  ? 220 ARG D CD  1 
ATOM   14233 N NE  . ARG D 1 160 ? -39.452  -0.650  45.560  1.00 101.42 ? 220 ARG D NE  1 
ATOM   14234 C CZ  . ARG D 1 160 ? -39.903  -0.138  46.714  1.00 103.71 ? 220 ARG D CZ  1 
ATOM   14235 N NH1 . ARG D 1 160 ? -40.344  -0.932  47.677  1.00 101.44 ? 220 ARG D NH1 1 
ATOM   14236 N NH2 . ARG D 1 160 ? -39.884  1.177   46.908  1.00 109.15 ? 220 ARG D NH2 1 
ATOM   14237 N N   . ASN D 1 161 ? -39.123  -3.541  41.073  1.00 47.93  ? 221 ASN D N   1 
ATOM   14238 C CA  . ASN D 1 161 ? -40.375  -4.185  40.615  1.00 45.92  ? 221 ASN D CA  1 
ATOM   14239 C C   . ASN D 1 161 ? -40.032  -5.445  39.813  1.00 48.73  ? 221 ASN D C   1 
ATOM   14240 O O   . ASN D 1 161 ? -40.899  -6.299  39.694  1.00 53.19  ? 221 ASN D O   1 
ATOM   14241 C CB  . ASN D 1 161 ? -41.223  -3.243  39.767  1.00 45.47  ? 221 ASN D CB  1 
ATOM   14242 C CG  . ASN D 1 161 ? -41.961  -2.172  40.538  1.00 50.25  ? 221 ASN D CG  1 
ATOM   14243 O OD1 . ASN D 1 161 ? -42.142  -2.251  41.762  1.00 48.11  ? 221 ASN D OD1 1 
ATOM   14244 N ND2 . ASN D 1 161 ? -42.398  -1.156  39.801  1.00 52.79  ? 221 ASN D ND2 1 
ATOM   14245 N N   . TRP D 1 162 ? -38.831  -5.557  39.245  1.00 48.60  ? 222 TRP D N   1 
ATOM   14246 C CA  . TRP D 1 162 ? -38.463  -6.760  38.452  1.00 49.13  ? 222 TRP D CA  1 
ATOM   14247 C C   . TRP D 1 162 ? -38.363  -7.944  39.422  1.00 42.08  ? 222 TRP D C   1 
ATOM   14248 O O   . TRP D 1 162 ? -37.656  -7.871  40.431  1.00 40.39  ? 222 TRP D O   1 
ATOM   14249 C CB  . TRP D 1 162 ? -37.189  -6.515  37.612  1.00 50.79  ? 222 TRP D CB  1 
ATOM   14250 C CG  . TRP D 1 162 ? -36.898  -7.600  36.620  1.00 51.75  ? 222 TRP D CG  1 
ATOM   14251 C CD1 . TRP D 1 162 ? -36.052  -8.667  36.771  1.00 57.84  ? 222 TRP D CD1 1 
ATOM   14252 C CD2 . TRP D 1 162 ? -37.496  -7.754  35.323  1.00 53.26  ? 222 TRP D CD2 1 
ATOM   14253 N NE1 . TRP D 1 162 ? -36.088  -9.477  35.665  1.00 58.28  ? 222 TRP D NE1 1 
ATOM   14254 C CE2 . TRP D 1 162 ? -36.978  -8.947  34.767  1.00 58.27  ? 222 TRP D CE2 1 
ATOM   14255 C CE3 . TRP D 1 162 ? -38.425  -7.008  34.589  1.00 54.64  ? 222 TRP D CE3 1 
ATOM   14256 C CZ2 . TRP D 1 162 ? -37.346  -9.384  33.492  1.00 64.63  ? 222 TRP D CZ2 1 
ATOM   14257 C CZ3 . TRP D 1 162 ? -38.785  -7.434  33.330  1.00 55.87  ? 222 TRP D CZ3 1 
ATOM   14258 C CH2 . TRP D 1 162 ? -38.248  -8.606  32.789  1.00 67.65  ? 222 TRP D CH2 1 
ATOM   14259 N N   . PRO D 1 163 ? -39.038  -9.067  39.133  1.00 35.76  ? 223 PRO D N   1 
ATOM   14260 C CA  . PRO D 1 163 ? -39.115  -10.198 40.037  1.00 46.39  ? 223 PRO D CA  1 
ATOM   14261 C C   . PRO D 1 163 ? -37.967  -11.211 40.012  1.00 51.89  ? 223 PRO D C   1 
ATOM   14262 O O   . PRO D 1 163 ? -38.221  -12.322 40.416  1.00 58.63  ? 223 PRO D O   1 
ATOM   14263 C CB  . PRO D 1 163 ? -40.391  -10.879 39.537  1.00 49.52  ? 223 PRO D CB  1 
ATOM   14264 C CG  . PRO D 1 163 ? -40.278  -10.763 38.052  1.00 48.35  ? 223 PRO D CG  1 
ATOM   14265 C CD  . PRO D 1 163 ? -39.732  -9.357  37.887  1.00 43.57  ? 223 PRO D CD  1 
ATOM   14266 N N   . HIS D 1 164 ? -36.781  -10.796 39.566  1.00 59.66  ? 224 HIS D N   1 
ATOM   14267 C CA  . HIS D 1 164 ? -35.491  -11.526 39.686  1.00 59.36  ? 224 HIS D CA  1 
ATOM   14268 C C   . HIS D 1 164 ? -34.425  -10.567 40.245  1.00 61.31  ? 224 HIS D C   1 
ATOM   14269 O O   . HIS D 1 164 ? -34.241  -9.441  39.663  1.00 56.99  ? 224 HIS D O   1 
ATOM   14270 C CB  . HIS D 1 164 ? -35.134  -12.155 38.337  1.00 59.73  ? 224 HIS D CB  1 
ATOM   14271 C CG  . HIS D 1 164 ? -35.919  -13.389 38.050  1.00 67.20  ? 224 HIS D CG  1 
ATOM   14272 N ND1 . HIS D 1 164 ? -35.684  -14.587 38.725  1.00 76.66  ? 224 HIS D ND1 1 
ATOM   14273 C CD2 . HIS D 1 164 ? -36.892  -13.644 37.148  1.00 70.50  ? 224 HIS D CD2 1 
ATOM   14274 C CE1 . HIS D 1 164 ? -36.481  -15.531 38.241  1.00 78.48  ? 224 HIS D CE1 1 
ATOM   14275 N NE2 . HIS D 1 164 ? -37.236  -14.978 37.269  1.00 73.48  ? 224 HIS D NE2 1 
ATOM   14276 N N   . ARG D 1 165 ? -33.735  -10.989 41.312  1.00 65.29  ? 225 ARG D N   1 
ATOM   14277 C CA  . ARG D 1 165 ? -32.726  -10.146 42.020  1.00 72.39  ? 225 ARG D CA  1 
ATOM   14278 C C   . ARG D 1 165 ? -31.318  -10.362 41.417  1.00 73.47  ? 225 ARG D C   1 
ATOM   14279 O O   . ARG D 1 165 ? -30.532  -9.370  41.331  1.00 53.48  ? 225 ARG D O   1 
ATOM   14280 C CB  . ARG D 1 165 ? -32.783  -10.376 43.537  1.00 72.00  ? 225 ARG D CB  1 
ATOM   14281 C CG  . ARG D 1 165 ? -31.904  -9.415  44.342  1.00 77.56  ? 225 ARG D CG  1 
ATOM   14282 C CD  . ARG D 1 165 ? -32.036  -7.918  44.043  1.00 72.05  ? 225 ARG D CD  1 
ATOM   14283 N NE  . ARG D 1 165 ? -30.816  -7.175  44.351  1.00 78.30  ? 225 ARG D NE  1 
ATOM   14284 C CZ  . ARG D 1 165 ? -30.602  -6.400  45.429  1.00 85.99  ? 225 ARG D CZ  1 
ATOM   14285 N NH1 . ARG D 1 165 ? -31.517  -6.217  46.368  1.00 94.96  ? 225 ARG D NH1 1 
ATOM   14286 N NH2 . ARG D 1 165 ? -29.445  -5.783  45.559  1.00 86.19  ? 225 ARG D NH2 1 
ATOM   14287 N N   . ASN D 1 166 ? -31.029  -11.590 40.977  1.00 72.62  ? 226 ASN D N   1 
ATOM   14288 C CA  . ASN D 1 166 ? -29.684  -12.046 40.527  1.00 66.35  ? 226 ASN D CA  1 
ATOM   14289 C C   . ASN D 1 166 ? -29.497  -11.754 39.024  1.00 61.73  ? 226 ASN D C   1 
ATOM   14290 O O   . ASN D 1 166 ? -29.528  -12.693 38.220  1.00 59.90  ? 226 ASN D O   1 
ATOM   14291 C CB  . ASN D 1 166 ? -29.524  -13.529 40.889  1.00 75.51  ? 226 ASN D CB  1 
ATOM   14292 C CG  . ASN D 1 166 ? -28.362  -14.227 40.203  1.00 81.31  ? 226 ASN D CG  1 
ATOM   14293 O OD1 . ASN D 1 166 ? -27.269  -13.660 40.088  1.00 85.26  ? 226 ASN D OD1 1 
ATOM   14294 N ND2 . ASN D 1 166 ? -28.617  -15.428 39.692  1.00 77.38  ? 226 ASN D ND2 1 
ATOM   14295 N N   . ILE D 1 167 ? -29.295  -10.497 38.637  1.00 61.69  ? 227 ILE D N   1 
ATOM   14296 C CA  . ILE D 1 167 ? -29.147  -10.094 37.201  1.00 57.20  ? 227 ILE D CA  1 
ATOM   14297 C C   . ILE D 1 167 ? -27.653  -10.058 36.847  1.00 56.93  ? 227 ILE D C   1 
ATOM   14298 O O   . ILE D 1 167 ? -26.883  -9.373  37.587  1.00 55.90  ? 227 ILE D O   1 
ATOM   14299 C CB  . ILE D 1 167 ? -29.862  -8.750  36.940  1.00 56.21  ? 227 ILE D CB  1 
ATOM   14300 C CG1 . ILE D 1 167 ? -31.380  -8.900  37.088  1.00 62.73  ? 227 ILE D CG1 1 
ATOM   14301 C CG2 . ILE D 1 167 ? -29.486  -8.189  35.582  1.00 54.57  ? 227 ILE D CG2 1 
ATOM   14302 C CD1 . ILE D 1 167 ? -31.964  -10.111 36.338  1.00 63.71  ? 227 ILE D CD1 1 
ATOM   14303 N N   . GLN D 1 168 ? -27.267  -10.770 35.776  1.00 55.17  ? 228 GLN D N   1 
ATOM   14304 C CA  . GLN D 1 168 ? -25.867  -10.903 35.262  1.00 54.07  ? 228 GLN D CA  1 
ATOM   14305 C C   . GLN D 1 168 ? -25.687  -10.122 33.948  1.00 52.75  ? 228 GLN D C   1 
ATOM   14306 O O   . GLN D 1 168 ? -24.616  -9.532  33.772  1.00 57.56  ? 228 GLN D O   1 
ATOM   14307 C CB  . GLN D 1 168 ? -25.522  -12.379 35.038  1.00 53.34  ? 228 GLN D CB  1 
ATOM   14308 C CG  . GLN D 1 168 ? -25.424  -13.167 36.333  1.00 54.84  ? 228 GLN D CG  1 
ATOM   14309 C CD  . GLN D 1 168 ? -25.161  -14.648 36.171  1.00 58.77  ? 228 GLN D CD  1 
ATOM   14310 O OE1 . GLN D 1 168 ? -25.101  -15.227 35.089  1.00 60.35  ? 228 GLN D OE1 1 
ATOM   14311 N NE2 . GLN D 1 168 ? -25.044  -15.307 37.298  1.00 62.58  ? 228 GLN D NE2 1 
ATOM   14312 N N   . VAL D 1 169 ? -26.680  -10.165 33.056  1.00 58.12  ? 229 VAL D N   1 
ATOM   14313 C CA  . VAL D 1 169 ? -26.692  -9.481  31.730  1.00 59.15  ? 229 VAL D CA  1 
ATOM   14314 C C   . VAL D 1 169 ? -27.890  -8.531  31.642  1.00 54.28  ? 229 VAL D C   1 
ATOM   14315 O O   . VAL D 1 169 ? -29.033  -8.996  31.692  1.00 48.96  ? 229 VAL D O   1 
ATOM   14316 C CB  . VAL D 1 169 ? -26.745  -10.477 30.562  1.00 65.87  ? 229 VAL D CB  1 
ATOM   14317 C CG1 . VAL D 1 169 ? -26.576  -9.738  29.247  1.00 76.30  ? 229 VAL D CG1 1 
ATOM   14318 C CG2 . VAL D 1 169 ? -25.719  -11.588 30.692  1.00 71.20  ? 229 VAL D CG2 1 
ATOM   14319 N N   . ILE D 1 170 ? -27.618  -7.243  31.492  1.00 53.02  ? 230 ILE D N   1 
ATOM   14320 C CA  . ILE D 1 170 ? -28.626  -6.218  31.105  1.00 54.87  ? 230 ILE D CA  1 
ATOM   14321 C C   . ILE D 1 170 ? -28.383  -5.893  29.640  1.00 54.03  ? 230 ILE D C   1 
ATOM   14322 O O   . ILE D 1 170 ? -27.221  -5.881  29.253  1.00 59.80  ? 230 ILE D O   1 
ATOM   14323 C CB  . ILE D 1 170 ? -28.549  -4.967  32.002  1.00 51.82  ? 230 ILE D CB  1 
ATOM   14324 C CG1 . ILE D 1 170 ? -29.118  -5.279  33.393  1.00 52.76  ? 230 ILE D CG1 1 
ATOM   14325 C CG2 . ILE D 1 170 ? -29.250  -3.768  31.345  1.00 51.02  ? 230 ILE D CG2 1 
ATOM   14326 C CD1 . ILE D 1 170 ? -28.806  -4.261  34.472  1.00 51.36  ? 230 ILE D CD1 1 
ATOM   14327 N N   . CYS D 1 171 ? -29.456  -5.703  28.874  1.00 53.70  ? 231 CYS D N   1 
ATOM   14328 C CA  . CYS D 1 171 ? -29.407  -5.200  27.487  1.00 51.73  ? 231 CYS D CA  1 
ATOM   14329 C C   . CYS D 1 171 ? -30.330  -3.983  27.387  1.00 48.94  ? 231 CYS D C   1 
ATOM   14330 O O   . CYS D 1 171 ? -31.518  -4.137  27.634  1.00 59.01  ? 231 CYS D O   1 
ATOM   14331 C CB  . CYS D 1 171 ? -29.748  -6.321  26.522  1.00 51.32  ? 231 CYS D CB  1 
ATOM   14332 S SG  . CYS D 1 171 ? -29.076  -5.946  24.888  1.00 76.24  ? 231 CYS D SG  1 
ATOM   14333 N N   . VAL D 1 172 ? -29.802  -2.809  27.077  1.00 46.66  ? 232 VAL D N   1 
ATOM   14334 C CA  . VAL D 1 172 ? -30.541  -1.521  27.234  1.00 50.06  ? 232 VAL D CA  1 
ATOM   14335 C C   . VAL D 1 172 ? -30.423  -0.688  25.967  1.00 51.03  ? 232 VAL D C   1 
ATOM   14336 O O   . VAL D 1 172 ? -29.310  -0.618  25.462  1.00 52.11  ? 232 VAL D O   1 
ATOM   14337 C CB  . VAL D 1 172 ? -29.998  -0.711  28.414  1.00 51.58  ? 232 VAL D CB  1 
ATOM   14338 C CG1 . VAL D 1 172 ? -28.501  -0.472  28.297  1.00 55.45  ? 232 VAL D CG1 1 
ATOM   14339 C CG2 . VAL D 1 172 ? -30.737  0.608   28.552  1.00 50.45  ? 232 VAL D CG2 1 
ATOM   14340 N N   . THR D 1 173 ? -31.520  -0.068  25.509  1.00 50.36  ? 233 THR D N   1 
ATOM   14341 C CA  . THR D 1 173 ? -31.562  0.869   24.342  1.00 47.39  ? 233 THR D CA  1 
ATOM   14342 C C   . THR D 1 173 ? -32.323  2.138   24.716  1.00 41.30  ? 233 THR D C   1 
ATOM   14343 O O   . THR D 1 173 ? -33.135  2.065   25.641  1.00 44.28  ? 233 THR D O   1 
ATOM   14344 C CB  . THR D 1 173 ? -32.208  0.225   23.118  1.00 48.70  ? 233 THR D CB  1 
ATOM   14345 O OG1 . THR D 1 173 ? -32.424  1.262   22.162  1.00 55.95  ? 233 THR D OG1 1 
ATOM   14346 C CG2 . THR D 1 173 ? -33.542  -0.413  23.396  1.00 52.05  ? 233 THR D CG2 1 
ATOM   14347 N N   . ASP D 1 174 ? -32.050  3.274   24.081  1.00 38.24  ? 234 ASP D N   1 
ATOM   14348 C CA  . ASP D 1 174 ? -32.917  4.466   24.277  1.00 42.96  ? 234 ASP D CA  1 
ATOM   14349 C C   . ASP D 1 174 ? -33.723  4.671   23.000  1.00 44.68  ? 234 ASP D C   1 
ATOM   14350 O O   . ASP D 1 174 ? -34.482  5.656   22.923  1.00 46.45  ? 234 ASP D O   1 
ATOM   14351 C CB  . ASP D 1 174 ? -32.157  5.702   24.743  1.00 46.50  ? 234 ASP D CB  1 
ATOM   14352 C CG  . ASP D 1 174 ? -31.383  6.388   23.657  1.00 49.78  ? 234 ASP D CG  1 
ATOM   14353 O OD1 . ASP D 1 174 ? -31.211  5.759   22.650  1.00 61.06  ? 234 ASP D OD1 1 
ATOM   14354 O OD2 . ASP D 1 174 ? -30.970  7.558   23.833  1.00 61.31  ? 234 ASP D OD2 1 
ATOM   14355 N N   . GLY D 1 175 ? -33.583  3.717   22.071  1.00 48.65  ? 235 GLY D N   1 
ATOM   14356 C CA  . GLY D 1 175 ? -34.403  3.593   20.855  1.00 46.95  ? 235 GLY D CA  1 
ATOM   14357 C C   . GLY D 1 175 ? -34.006  4.557   19.751  1.00 47.64  ? 235 GLY D C   1 
ATOM   14358 O O   . GLY D 1 175 ? -34.722  4.561   18.731  1.00 43.68  ? 235 GLY D O   1 
ATOM   14359 N N   . GLU D 1 176 ? -32.917  5.334   19.915  1.00 54.70  ? 236 GLU D N   1 
ATOM   14360 C CA  . GLU D 1 176 ? -32.567  6.476   19.009  1.00 55.99  ? 236 GLU D CA  1 
ATOM   14361 C C   . GLU D 1 176 ? -32.136  5.973   17.627  1.00 58.41  ? 236 GLU D C   1 
ATOM   14362 O O   . GLU D 1 176 ? -32.412  6.716   16.656  1.00 67.18  ? 236 GLU D O   1 
ATOM   14363 C CB  . GLU D 1 176 ? -31.506  7.429   19.547  1.00 58.06  ? 236 GLU D CB  1 
ATOM   14364 C CG  . GLU D 1 176 ? -31.439  8.704   18.717  1.00 58.53  ? 236 GLU D CG  1 
ATOM   14365 C CD  . GLU D 1 176 ? -31.097  9.989   19.456  1.00 65.56  ? 236 GLU D CD  1 
ATOM   14366 O OE1 . GLU D 1 176 ? -30.580  9.894   20.615  1.00 72.29  ? 236 GLU D OE1 1 
ATOM   14367 O OE2 . GLU D 1 176 ? -31.407  11.075  18.897  1.00 53.60  ? 236 GLU D OE2 1 
ATOM   14368 N N   . ARG D 1 177 ? -31.488  4.803   17.520  1.00 52.44  ? 237 ARG D N   1 
ATOM   14369 C CA  . ARG D 1 177 ? -31.044  4.265   16.207  1.00 54.53  ? 237 ARG D CA  1 
ATOM   14370 C C   . ARG D 1 177 ? -31.309  2.765   16.146  1.00 48.61  ? 237 ARG D C   1 
ATOM   14371 O O   . ARG D 1 177 ? -30.349  2.008   16.144  1.00 45.87  ? 237 ARG D O   1 
ATOM   14372 C CB  . ARG D 1 177 ? -29.556  4.539   15.951  1.00 56.52  ? 237 ARG D CB  1 
ATOM   14373 C CG  . ARG D 1 177 ? -29.201  6.002   15.772  1.00 56.56  ? 237 ARG D CG  1 
ATOM   14374 C CD  . ARG D 1 177 ? -29.450  6.492   14.387  1.00 62.61  ? 237 ARG D CD  1 
ATOM   14375 N NE  . ARG D 1 177 ? -29.279  7.939   14.397  1.00 67.26  ? 237 ARG D NE  1 
ATOM   14376 C CZ  . ARG D 1 177 ? -30.260  8.829   14.387  1.00 65.29  ? 237 ARG D CZ  1 
ATOM   14377 N NH1 . ARG D 1 177 ? -31.520  8.429   14.357  1.00 62.20  ? 237 ARG D NH1 1 
ATOM   14378 N NH2 . ARG D 1 177 ? -29.972  10.122  14.412  1.00 71.03  ? 237 ARG D NH2 1 
ATOM   14379 N N   . ILE D 1 178 ? -32.568  2.355   16.040  1.00 50.30  ? 238 ILE D N   1 
ATOM   14380 C CA  . ILE D 1 178 ? -32.922  0.907   15.966  1.00 53.68  ? 238 ILE D CA  1 
ATOM   14381 C C   . ILE D 1 178 ? -32.541  0.396   14.582  1.00 48.32  ? 238 ILE D C   1 
ATOM   14382 O O   . ILE D 1 178 ? -33.131  0.878   13.615  1.00 46.31  ? 238 ILE D O   1 
ATOM   14383 C CB  . ILE D 1 178 ? -34.414  0.686   16.261  1.00 57.75  ? 238 ILE D CB  1 
ATOM   14384 C CG1 . ILE D 1 178 ? -34.781  1.196   17.665  1.00 60.73  ? 238 ILE D CG1 1 
ATOM   14385 C CG2 . ILE D 1 178 ? -34.809  -0.775  16.018  1.00 52.22  ? 238 ILE D CG2 1 
ATOM   14386 C CD1 . ILE D 1 178 ? -34.048  0.536   18.804  1.00 55.52  ? 238 ILE D CD1 1 
ATOM   14387 N N   . LEU D 1 179 ? -31.560  -0.509  14.505  1.00 51.26  ? 239 LEU D N   1 
ATOM   14388 C CA  . LEU D 1 179 ? -30.992  -1.032  13.229  1.00 53.55  ? 239 LEU D CA  1 
ATOM   14389 C C   . LEU D 1 179 ? -30.721  0.167   12.300  1.00 56.50  ? 239 LEU D C   1 
ATOM   14390 O O   . LEU D 1 179 ? -30.287  1.219   12.826  1.00 63.67  ? 239 LEU D O   1 
ATOM   14391 C CB  . LEU D 1 179 ? -31.980  -2.037  12.624  1.00 57.38  ? 239 LEU D CB  1 
ATOM   14392 C CG  . LEU D 1 179 ? -32.336  -3.297  13.408  1.00 57.01  ? 239 LEU D CG  1 
ATOM   14393 C CD1 . LEU D 1 179 ? -32.042  -4.575  12.625  1.00 58.38  ? 239 LEU D CD1 1 
ATOM   14394 C CD2 . LEU D 1 179 ? -31.633  -3.336  14.747  1.00 70.39  ? 239 LEU D CD2 1 
ATOM   14395 N N   . GLY D 1 180 ? -30.978  0.064   10.991  1.00 61.69  ? 240 GLY D N   1 
ATOM   14396 C CA  . GLY D 1 180 ? -30.913  1.215   10.070  1.00 59.55  ? 240 GLY D CA  1 
ATOM   14397 C C   . GLY D 1 180 ? -32.261  1.916   9.895   1.00 60.73  ? 240 GLY D C   1 
ATOM   14398 O O   . GLY D 1 180 ? -32.449  2.537   8.828   1.00 63.34  ? 240 GLY D O   1 
ATOM   14399 N N   . LEU D 1 181 ? -33.188  1.814   10.861  1.00 54.16  ? 241 LEU D N   1 
ATOM   14400 C CA  . LEU D 1 181 ? -34.575  2.356   10.750  1.00 50.53  ? 241 LEU D CA  1 
ATOM   14401 C C   . LEU D 1 181 ? -34.712  3.710   11.462  1.00 52.06  ? 241 LEU D C   1 
ATOM   14402 O O   . LEU D 1 181 ? -35.803  4.309   11.400  1.00 49.50  ? 241 LEU D O   1 
ATOM   14403 C CB  . LEU D 1 181 ? -35.545  1.319   11.319  1.00 50.36  ? 241 LEU D CB  1 
ATOM   14404 C CG  . LEU D 1 181 ? -35.417  -0.072  10.691  1.00 48.87  ? 241 LEU D CG  1 
ATOM   14405 C CD1 . LEU D 1 181 ? -36.275  -1.107  11.414  1.00 52.34  ? 241 LEU D CD1 1 
ATOM   14406 C CD2 . LEU D 1 181 ? -35.797  -0.036  9.236   1.00 49.07  ? 241 LEU D CD2 1 
ATOM   14407 N N   . GLY D 1 182 ? -33.651  4.184   12.118  1.00 56.29  ? 242 GLY D N   1 
ATOM   14408 C CA  . GLY D 1 182 ? -33.647  5.439   12.896  1.00 52.89  ? 242 GLY D CA  1 
ATOM   14409 C C   . GLY D 1 182 ? -34.396  5.322   14.220  1.00 61.00  ? 242 GLY D C   1 
ATOM   14410 O O   . GLY D 1 182 ? -34.356  4.219   14.868  1.00 58.59  ? 242 GLY D O   1 
ATOM   14411 N N   . ASP D 1 183 ? -35.055  6.427   14.608  1.00 64.66  ? 243 ASP D N   1 
ATOM   14412 C CA  . ASP D 1 183 ? -35.654  6.689   15.950  1.00 56.78  ? 243 ASP D CA  1 
ATOM   14413 C C   . ASP D 1 183 ? -37.038  6.024   16.076  1.00 54.13  ? 243 ASP D C   1 
ATOM   14414 O O   . ASP D 1 183 ? -38.006  6.485   15.437  1.00 49.24  ? 243 ASP D O   1 
ATOM   14415 C CB  . ASP D 1 183 ? -35.734  8.203   16.141  1.00 54.27  ? 243 ASP D CB  1 
ATOM   14416 C CG  . ASP D 1 183 ? -36.067  8.652   17.538  1.00 56.07  ? 243 ASP D CG  1 
ATOM   14417 O OD1 . ASP D 1 183 ? -36.553  7.810   18.325  1.00 50.87  ? 243 ASP D OD1 1 
ATOM   14418 O OD2 . ASP D 1 183 ? -35.808  9.840   17.820  1.00 69.25  ? 243 ASP D OD2 1 
ATOM   14419 N N   . LEU D 1 184 ? -37.143  4.960   16.870  1.00 54.58  ? 244 LEU D N   1 
ATOM   14420 C CA  . LEU D 1 184 ? -38.442  4.284   17.150  1.00 55.59  ? 244 LEU D CA  1 
ATOM   14421 C C   . LEU D 1 184 ? -38.806  4.516   18.620  1.00 62.94  ? 244 LEU D C   1 
ATOM   14422 O O   . LEU D 1 184 ? -39.672  3.804   19.156  1.00 69.35  ? 244 LEU D O   1 
ATOM   14423 C CB  . LEU D 1 184 ? -38.319  2.803   16.795  1.00 49.32  ? 244 LEU D CB  1 
ATOM   14424 C CG  . LEU D 1 184 ? -38.151  2.537   15.303  1.00 58.08  ? 244 LEU D CG  1 
ATOM   14425 C CD1 . LEU D 1 184 ? -38.141  1.039   14.991  1.00 67.48  ? 244 LEU D CD1 1 
ATOM   14426 C CD2 . LEU D 1 184 ? -39.235  3.244   14.502  1.00 53.36  ? 244 LEU D CD2 1 
ATOM   14427 N N   . GLY D 1 185 ? -38.172  5.516   19.242  1.00 68.35  ? 245 GLY D N   1 
ATOM   14428 C CA  . GLY D 1 185 ? -38.415  5.861   20.650  1.00 62.26  ? 245 GLY D CA  1 
ATOM   14429 C C   . GLY D 1 185 ? -38.635  4.606   21.468  1.00 62.08  ? 245 GLY D C   1 
ATOM   14430 O O   . GLY D 1 185 ? -37.895  3.611   21.270  1.00 64.96  ? 245 GLY D O   1 
ATOM   14431 N N   . CYS D 1 186 ? -39.677  4.621   22.290  1.00 61.55  ? 246 CYS D N   1 
ATOM   14432 C CA  . CYS D 1 186 ? -39.964  3.592   23.321  1.00 58.24  ? 246 CYS D CA  1 
ATOM   14433 C C   . CYS D 1 186 ? -40.211  2.212   22.675  1.00 56.11  ? 246 CYS D C   1 
ATOM   14434 O O   . CYS D 1 186 ? -40.137  1.191   23.396  1.00 53.34  ? 246 CYS D O   1 
ATOM   14435 C CB  . CYS D 1 186 ? -41.141  4.055   24.171  1.00 52.35  ? 246 CYS D CB  1 
ATOM   14436 S SG  . CYS D 1 186 ? -41.148  3.312   25.817  1.00 49.57  ? 246 CYS D SG  1 
ATOM   14437 N N   . GLN D 1 187 ? -40.476  2.162   21.368  1.00 54.95  ? 247 GLN D N   1 
ATOM   14438 C CA  . GLN D 1 187 ? -40.795  0.892   20.661  1.00 56.00  ? 247 GLN D CA  1 
ATOM   14439 C C   . GLN D 1 187 ? -39.484  0.164   20.308  1.00 60.48  ? 247 GLN D C   1 
ATOM   14440 O O   . GLN D 1 187 ? -39.547  -0.942  19.717  1.00 55.39  ? 247 GLN D O   1 
ATOM   14441 C CB  . GLN D 1 187 ? -41.709  1.162   19.457  1.00 54.06  ? 247 GLN D CB  1 
ATOM   14442 C CG  . GLN D 1 187 ? -43.092  1.700   19.843  1.00 57.32  ? 247 GLN D CG  1 
ATOM   14443 C CD  . GLN D 1 187 ? -44.098  1.711   18.707  1.00 46.14  ? 247 GLN D CD  1 
ATOM   14444 O OE1 . GLN D 1 187 ? -43.835  1.259   17.618  1.00 44.28  ? 247 GLN D OE1 1 
ATOM   14445 N NE2 . GLN D 1 187 ? -45.280  2.237   18.934  1.00 45.23  ? 247 GLN D NE2 1 
ATOM   14446 N N   . GLY D 1 188 ? -38.329  0.725   20.689  1.00 61.36  ? 248 GLY D N   1 
ATOM   14447 C CA  . GLY D 1 188 ? -37.014  0.066   20.543  1.00 64.01  ? 248 GLY D CA  1 
ATOM   14448 C C   . GLY D 1 188 ? -36.908  -1.256  21.321  1.00 63.95  ? 248 GLY D C   1 
ATOM   14449 O O   . GLY D 1 188 ? -35.997  -2.073  21.035  1.00 46.66  ? 248 GLY D O   1 
ATOM   14450 N N   . MET D 1 189 ? -37.810  -1.483  22.278  1.00 60.29  ? 249 MET D N   1 
ATOM   14451 C CA  . MET D 1 189 ? -37.716  -2.629  23.220  1.00 61.25  ? 249 MET D CA  1 
ATOM   14452 C C   . MET D 1 189 ? -37.553  -3.967  22.459  1.00 54.87  ? 249 MET D C   1 
ATOM   14453 O O   . MET D 1 189 ? -37.037  -4.926  23.042  1.00 55.81  ? 249 MET D O   1 
ATOM   14454 C CB  . MET D 1 189 ? -38.956  -2.657  24.130  1.00 59.10  ? 249 MET D CB  1 
ATOM   14455 C CG  . MET D 1 189 ? -38.990  -3.831  25.115  1.00 55.76  ? 249 MET D CG  1 
ATOM   14456 S SD  . MET D 1 189 ? -37.639  -3.830  26.281  1.00 49.85  ? 249 MET D SD  1 
ATOM   14457 C CE  . MET D 1 189 ? -38.436  -3.058  27.686  1.00 59.73  ? 249 MET D CE  1 
ATOM   14458 N N   . GLY D 1 190 ? -37.971  -4.063  21.205  1.00 52.58  ? 250 GLY D N   1 
ATOM   14459 C CA  . GLY D 1 190 ? -37.926  -5.343  20.477  1.00 66.56  ? 250 GLY D CA  1 
ATOM   14460 C C   . GLY D 1 190 ? -36.516  -5.893  20.419  1.00 68.15  ? 250 GLY D C   1 
ATOM   14461 O O   . GLY D 1 190 ? -36.359  -7.147  20.422  1.00 80.32  ? 250 GLY D O   1 
ATOM   14462 N N   . ILE D 1 191 ? -35.540  -4.978  20.376  1.00 61.94  ? 251 ILE D N   1 
ATOM   14463 C CA  . ILE D 1 191 ? -34.082  -5.253  20.193  1.00 64.71  ? 251 ILE D CA  1 
ATOM   14464 C C   . ILE D 1 191 ? -33.532  -5.894  21.469  1.00 57.36  ? 251 ILE D C   1 
ATOM   14465 O O   . ILE D 1 191 ? -33.117  -7.053  21.455  1.00 59.66  ? 251 ILE D O   1 
ATOM   14466 C CB  . ILE D 1 191 ? -33.345  -3.954  19.772  1.00 68.96  ? 251 ILE D CB  1 
ATOM   14467 C CG1 . ILE D 1 191 ? -33.808  -3.425  18.407  1.00 67.22  ? 251 ILE D CG1 1 
ATOM   14468 C CG2 . ILE D 1 191 ? -31.837  -4.150  19.806  1.00 70.66  ? 251 ILE D CG2 1 
ATOM   14469 C CD1 . ILE D 1 191 ? -33.718  -4.443  17.276  1.00 73.21  ? 251 ILE D CD1 1 
ATOM   14470 N N   . PRO D 1 192 ? -33.503  -5.181  22.616  1.00 48.87  ? 252 PRO D N   1 
ATOM   14471 C CA  . PRO D 1 192 ? -33.006  -5.775  23.848  1.00 48.40  ? 252 PRO D CA  1 
ATOM   14472 C C   . PRO D 1 192 ? -33.639  -7.143  24.110  1.00 52.85  ? 252 PRO D C   1 
ATOM   14473 O O   . PRO D 1 192 ? -32.935  -8.024  24.553  1.00 58.57  ? 252 PRO D O   1 
ATOM   14474 C CB  . PRO D 1 192 ? -33.413  -4.771  24.929  1.00 48.93  ? 252 PRO D CB  1 
ATOM   14475 C CG  . PRO D 1 192 ? -33.442  -3.457  24.199  1.00 52.00  ? 252 PRO D CG  1 
ATOM   14476 C CD  . PRO D 1 192 ? -33.912  -3.778  22.797  1.00 52.38  ? 252 PRO D CD  1 
ATOM   14477 N N   . VAL D 1 193 ? -34.935  -7.288  23.836  1.00 53.28  ? 253 VAL D N   1 
ATOM   14478 C CA  . VAL D 1 193 ? -35.659  -8.559  24.127  1.00 54.91  ? 253 VAL D CA  1 
ATOM   14479 C C   . VAL D 1 193 ? -35.107  -9.627  23.172  1.00 54.95  ? 253 VAL D C   1 
ATOM   14480 O O   . VAL D 1 193 ? -34.903  -10.798 23.590  1.00 57.02  ? 253 VAL D O   1 
ATOM   14481 C CB  . VAL D 1 193 ? -37.189  -8.414  24.043  1.00 48.31  ? 253 VAL D CB  1 
ATOM   14482 C CG1 . VAL D 1 193 ? -37.843  -9.782  24.224  1.00 55.37  ? 253 VAL D CG1 1 
ATOM   14483 C CG2 . VAL D 1 193 ? -37.737  -7.417  25.059  1.00 41.06  ? 253 VAL D CG2 1 
ATOM   14484 N N   . GLY D 1 194 ? -34.816  -9.212  21.948  1.00 53.81  ? 254 GLY D N   1 
ATOM   14485 C CA  . GLY D 1 194 ? -34.257  -10.107 20.926  1.00 59.36  ? 254 GLY D CA  1 
ATOM   14486 C C   . GLY D 1 194 ? -32.866  -10.564 21.324  1.00 58.75  ? 254 GLY D C   1 
ATOM   14487 O O   . GLY D 1 194 ? -32.635  -11.809 21.382  1.00 47.90  ? 254 GLY D O   1 
ATOM   14488 N N   . LYS D 1 195 ? -31.977  -9.592  21.585  1.00 51.43  ? 255 LYS D N   1 
ATOM   14489 C CA  . LYS D 1 195 ? -30.566  -9.853  21.920  1.00 47.76  ? 255 LYS D CA  1 
ATOM   14490 C C   . LYS D 1 195 ? -30.544  -10.903 23.034  1.00 50.43  ? 255 LYS D C   1 
ATOM   14491 O O   . LYS D 1 195 ? -29.877  -11.941 22.881  1.00 46.08  ? 255 LYS D O   1 
ATOM   14492 C CB  . LYS D 1 195 ? -29.893  -8.560  22.387  1.00 49.35  ? 255 LYS D CB  1 
ATOM   14493 C CG  . LYS D 1 195 ? -29.733  -7.457  21.346  1.00 48.78  ? 255 LYS D CG  1 
ATOM   14494 C CD  . LYS D 1 195 ? -28.636  -7.659  20.336  1.00 48.61  ? 255 LYS D CD  1 
ATOM   14495 C CE  . LYS D 1 195 ? -28.808  -6.748  19.135  1.00 52.75  ? 255 LYS D CE  1 
ATOM   14496 N NZ  . LYS D 1 195 ? -27.705  -6.830  18.149  1.00 55.30  ? 255 LYS D NZ  1 
ATOM   14497 N N   . LEU D 1 196 ? -31.298  -10.645 24.102  1.00 50.13  ? 256 LEU D N   1 
ATOM   14498 C CA  . LEU D 1 196 ? -31.227  -11.432 25.352  1.00 51.52  ? 256 LEU D CA  1 
ATOM   14499 C C   . LEU D 1 196 ? -31.764  -12.852 25.120  1.00 46.67  ? 256 LEU D C   1 
ATOM   14500 O O   . LEU D 1 196 ? -31.221  -13.776 25.711  1.00 50.01  ? 256 LEU D O   1 
ATOM   14501 C CB  . LEU D 1 196 ? -31.961  -10.661 26.447  1.00 54.17  ? 256 LEU D CB  1 
ATOM   14502 C CG  . LEU D 1 196 ? -31.188  -9.447  26.981  1.00 62.17  ? 256 LEU D CG  1 
ATOM   14503 C CD1 . LEU D 1 196 ? -31.968  -8.721  28.085  1.00 67.79  ? 256 LEU D CD1 1 
ATOM   14504 C CD2 . LEU D 1 196 ? -29.801  -9.842  27.487  1.00 57.48  ? 256 LEU D CD2 1 
ATOM   14505 N N   . ALA D 1 197 ? -32.750  -13.040 24.256  1.00 45.11  ? 257 ALA D N   1 
ATOM   14506 C CA  . ALA D 1 197 ? -33.223  -14.388 23.869  1.00 47.51  ? 257 ALA D CA  1 
ATOM   14507 C C   . ALA D 1 197 ? -32.039  -15.137 23.246  1.00 52.87  ? 257 ALA D C   1 
ATOM   14508 O O   . ALA D 1 197 ? -31.890  -16.360 23.464  1.00 40.98  ? 257 ALA D O   1 
ATOM   14509 C CB  . ALA D 1 197 ? -34.378  -14.279 22.902  1.00 52.90  ? 257 ALA D CB  1 
ATOM   14510 N N   . LEU D 1 198 ? -31.218  -14.410 22.479  1.00 62.41  ? 258 LEU D N   1 
ATOM   14511 C CA  . LEU D 1 198 ? -30.059  -14.983 21.744  1.00 59.32  ? 258 LEU D CA  1 
ATOM   14512 C C   . LEU D 1 198 ? -28.962  -15.285 22.759  1.00 53.59  ? 258 LEU D C   1 
ATOM   14513 O O   . LEU D 1 198 ? -28.353  -16.363 22.683  1.00 61.57  ? 258 LEU D O   1 
ATOM   14514 C CB  . LEU D 1 198 ? -29.591  -14.014 20.649  1.00 61.96  ? 258 LEU D CB  1 
ATOM   14515 C CG  . LEU D 1 198 ? -30.151  -14.289 19.249  1.00 66.07  ? 258 LEU D CG  1 
ATOM   14516 C CD1 . LEU D 1 198 ? -31.670  -14.334 19.233  1.00 71.43  ? 258 LEU D CD1 1 
ATOM   14517 C CD2 . LEU D 1 198 ? -29.642  -13.254 18.257  1.00 67.61  ? 258 LEU D CD2 1 
ATOM   14518 N N   . TYR D 1 199 ? -28.750  -14.379 23.697  1.00 46.93  ? 259 TYR D N   1 
ATOM   14519 C CA  . TYR D 1 199 ? -27.822  -14.606 24.826  1.00 53.39  ? 259 TYR D CA  1 
ATOM   14520 C C   . TYR D 1 199 ? -28.083  -15.987 25.425  1.00 54.89  ? 259 TYR D C   1 
ATOM   14521 O O   . TYR D 1 199 ? -27.123  -16.579 25.899  1.00 61.17  ? 259 TYR D O   1 
ATOM   14522 C CB  . TYR D 1 199 ? -27.983  -13.544 25.910  1.00 53.08  ? 259 TYR D CB  1 
ATOM   14523 C CG  . TYR D 1 199 ? -26.912  -12.492 25.892  1.00 50.73  ? 259 TYR D CG  1 
ATOM   14524 C CD1 . TYR D 1 199 ? -25.651  -12.765 26.388  1.00 51.14  ? 259 TYR D CD1 1 
ATOM   14525 C CD2 . TYR D 1 199 ? -27.172  -11.220 25.405  1.00 53.12  ? 259 TYR D CD2 1 
ATOM   14526 C CE1 . TYR D 1 199 ? -24.661  -11.796 26.384  1.00 56.52  ? 259 TYR D CE1 1 
ATOM   14527 C CE2 . TYR D 1 199 ? -26.203  -10.227 25.420  1.00 52.94  ? 259 TYR D CE2 1 
ATOM   14528 C CZ  . TYR D 1 199 ? -24.945  -10.523 25.908  1.00 57.95  ? 259 TYR D CZ  1 
ATOM   14529 O OH  . TYR D 1 199 ? -24.001  -9.545  25.909  1.00 67.33  ? 259 TYR D OH  1 
ATOM   14530 N N   . THR D 1 200 ? -29.338  -16.436 25.462  1.00 51.89  ? 260 THR D N   1 
ATOM   14531 C CA  . THR D 1 200 ? -29.736  -17.732 26.074  1.00 54.87  ? 260 THR D CA  1 
ATOM   14532 C C   . THR D 1 200 ? -29.587  -18.857 25.037  1.00 59.47  ? 260 THR D C   1 
ATOM   14533 O O   . THR D 1 200 ? -28.997  -19.915 25.372  1.00 53.90  ? 260 THR D O   1 
ATOM   14534 C CB  . THR D 1 200 ? -31.171  -17.704 26.630  1.00 56.04  ? 260 THR D CB  1 
ATOM   14535 O OG1 . THR D 1 200 ? -31.281  -16.657 27.602  1.00 55.65  ? 260 THR D OG1 1 
ATOM   14536 C CG2 . THR D 1 200 ? -31.612  -19.045 27.206  1.00 48.19  ? 260 THR D CG2 1 
ATOM   14537 N N   . ALA D 1 201 ? -30.158  -18.651 23.849  1.00 53.53  ? 261 ALA D N   1 
ATOM   14538 C CA  . ALA D 1 201 ? -30.263  -19.684 22.801  1.00 53.41  ? 261 ALA D CA  1 
ATOM   14539 C C   . ALA D 1 201 ? -28.866  -19.960 22.236  1.00 59.35  ? 261 ALA D C   1 
ATOM   14540 O O   . ALA D 1 201 ? -28.542  -21.147 22.068  1.00 54.92  ? 261 ALA D O   1 
ATOM   14541 C CB  . ALA D 1 201 ? -31.230  -19.205 21.747  1.00 56.88  ? 261 ALA D CB  1 
ATOM   14542 N N   . LEU D 1 202 ? -28.083  -18.897 21.957  1.00 66.32  ? 262 LEU D N   1 
ATOM   14543 C CA  . LEU D 1 202 ? -26.746  -18.967 21.291  1.00 67.60  ? 262 LEU D CA  1 
ATOM   14544 C C   . LEU D 1 202 ? -25.625  -19.111 22.319  1.00 62.41  ? 262 LEU D C   1 
ATOM   14545 O O   . LEU D 1 202 ? -24.689  -19.893 22.046  1.00 59.44  ? 262 LEU D O   1 
ATOM   14546 C CB  . LEU D 1 202 ? -26.491  -17.707 20.456  1.00 64.29  ? 262 LEU D CB  1 
ATOM   14547 C CG  . LEU D 1 202 ? -27.600  -17.298 19.485  1.00 64.29  ? 262 LEU D CG  1 
ATOM   14548 C CD1 . LEU D 1 202 ? -27.160  -16.098 18.660  1.00 68.03  ? 262 LEU D CD1 1 
ATOM   14549 C CD2 . LEU D 1 202 ? -28.028  -18.445 18.577  1.00 64.95  ? 262 LEU D CD2 1 
ATOM   14550 N N   . GLY D 1 203 ? -25.716  -18.372 23.431  1.00 65.83  ? 263 GLY D N   1 
ATOM   14551 C CA  . GLY D 1 203 ? -24.634  -18.244 24.435  1.00 75.05  ? 263 GLY D CA  1 
ATOM   14552 C C   . GLY D 1 203 ? -24.781  -19.183 25.637  1.00 75.45  ? 263 GLY D C   1 
ATOM   14553 O O   . GLY D 1 203 ? -23.756  -19.531 26.231  1.00 75.36  ? 263 GLY D O   1 
ATOM   14554 N N   . GLY D 1 204 ? -26.009  -19.534 26.026  1.00 67.51  ? 264 GLY D N   1 
ATOM   14555 C CA  . GLY D 1 204 ? -26.304  -20.435 27.151  1.00 59.02  ? 264 GLY D CA  1 
ATOM   14556 C C   . GLY D 1 204 ? -26.442  -19.718 28.479  1.00 52.53  ? 264 GLY D C   1 
ATOM   14557 O O   . GLY D 1 204 ? -26.545  -20.423 29.497  1.00 50.16  ? 264 GLY D O   1 
ATOM   14558 N N   . VAL D 1 205 ? -26.507  -18.388 28.482  1.00 52.17  ? 265 VAL D N   1 
ATOM   14559 C CA  . VAL D 1 205 ? -26.879  -17.577 29.688  1.00 53.73  ? 265 VAL D CA  1 
ATOM   14560 C C   . VAL D 1 205 ? -28.270  -18.024 30.160  1.00 46.29  ? 265 VAL D C   1 
ATOM   14561 O O   . VAL D 1 205 ? -29.125  -18.109 29.339  1.00 56.31  ? 265 VAL D O   1 
ATOM   14562 C CB  . VAL D 1 205 ? -26.859  -16.073 29.339  1.00 53.84  ? 265 VAL D CB  1 
ATOM   14563 C CG1 . VAL D 1 205 ? -27.038  -15.195 30.556  1.00 54.75  ? 265 VAL D CG1 1 
ATOM   14564 C CG2 . VAL D 1 205 ? -25.587  -15.679 28.619  1.00 55.85  ? 265 VAL D CG2 1 
ATOM   14565 N N   . ASP D 1 206 ? -28.504  -18.282 31.435  1.00 54.87  ? 266 ASP D N   1 
ATOM   14566 C CA  . ASP D 1 206 ? -29.867  -18.551 31.981  1.00 65.26  ? 266 ASP D CA  1 
ATOM   14567 C C   . ASP D 1 206 ? -30.791  -17.357 31.681  1.00 74.31  ? 266 ASP D C   1 
ATOM   14568 O O   . ASP D 1 206 ? -30.397  -16.185 31.776  1.00 65.71  ? 266 ASP D O   1 
ATOM   14569 C CB  . ASP D 1 206 ? -29.823  -18.872 33.483  1.00 69.91  ? 266 ASP D CB  1 
ATOM   14570 C CG  . ASP D 1 206 ? -31.160  -19.315 34.059  1.00 80.98  ? 266 ASP D CG  1 
ATOM   14571 O OD1 . ASP D 1 206 ? -31.820  -20.159 33.431  1.00 83.87  ? 266 ASP D OD1 1 
ATOM   14572 O OD2 . ASP D 1 206 ? -31.567  -18.754 35.089  1.00 91.24  ? 266 ASP D OD2 1 
ATOM   14573 N N   . PRO D 1 207 ? -32.060  -17.601 31.261  1.00 74.38  ? 267 PRO D N   1 
ATOM   14574 C CA  . PRO D 1 207 ? -32.969  -16.496 30.950  1.00 66.57  ? 267 PRO D CA  1 
ATOM   14575 C C   . PRO D 1 207 ? -33.188  -15.566 32.152  1.00 61.74  ? 267 PRO D C   1 
ATOM   14576 O O   . PRO D 1 207 ? -33.307  -14.372 32.007  1.00 53.16  ? 267 PRO D O   1 
ATOM   14577 C CB  . PRO D 1 207 ? -34.271  -17.200 30.556  1.00 72.62  ? 267 PRO D CB  1 
ATOM   14578 C CG  . PRO D 1 207 ? -33.840  -18.606 30.121  1.00 73.09  ? 267 PRO D CG  1 
ATOM   14579 C CD  . PRO D 1 207 ? -32.629  -18.927 30.958  1.00 67.51  ? 267 PRO D CD  1 
ATOM   14580 N N   . SER D 1 208 ? -33.236  -16.147 33.343  1.00 70.76  ? 268 SER D N   1 
ATOM   14581 C CA  . SER D 1 208 ? -33.713  -15.455 34.569  1.00 70.39  ? 268 SER D CA  1 
ATOM   14582 C C   . SER D 1 208 ? -32.678  -14.432 35.032  1.00 63.96  ? 268 SER D C   1 
ATOM   14583 O O   . SER D 1 208 ? -33.058  -13.548 35.794  1.00 61.87  ? 268 SER D O   1 
ATOM   14584 C CB  . SER D 1 208 ? -34.095  -16.429 35.652  1.00 74.93  ? 268 SER D CB  1 
ATOM   14585 O OG  . SER D 1 208 ? -33.382  -17.645 35.500  1.00 81.71  ? 268 SER D OG  1 
ATOM   14586 N N   . VAL D 1 209 ? -31.443  -14.500 34.537  1.00 59.48  ? 269 VAL D N   1 
ATOM   14587 C CA  . VAL D 1 209 ? -30.365  -13.535 34.916  1.00 51.99  ? 269 VAL D CA  1 
ATOM   14588 C C   . VAL D 1 209 ? -30.299  -12.399 33.885  1.00 51.65  ? 269 VAL D C   1 
ATOM   14589 O O   . VAL D 1 209 ? -29.449  -11.508 34.076  1.00 51.24  ? 269 VAL D O   1 
ATOM   14590 C CB  . VAL D 1 209 ? -29.003  -14.231 35.090  1.00 50.17  ? 269 VAL D CB  1 
ATOM   14591 C CG1 . VAL D 1 209 ? -29.090  -15.381 36.072  1.00 56.73  ? 269 VAL D CG1 1 
ATOM   14592 C CG2 . VAL D 1 209 ? -28.438  -14.741 33.799  1.00 48.96  ? 269 VAL D CG2 1 
ATOM   14593 N N   . CYS D 1 210 ? -31.166  -12.418 32.860  1.00 46.68  ? 270 CYS D N   1 
ATOM   14594 C CA  . CYS D 1 210 ? -31.167  -11.464 31.715  1.00 49.58  ? 270 CYS D CA  1 
ATOM   14595 C C   . CYS D 1 210 ? -32.285  -10.445 31.896  1.00 47.46  ? 270 CYS D C   1 
ATOM   14596 O O   . CYS D 1 210 ? -33.326  -10.877 32.269  1.00 50.86  ? 270 CYS D O   1 
ATOM   14597 C CB  . CYS D 1 210 ? -31.332  -12.190 30.391  1.00 50.76  ? 270 CYS D CB  1 
ATOM   14598 S SG  . CYS D 1 210 ? -30.044  -13.436 30.146  1.00 60.51  ? 270 CYS D SG  1 
ATOM   14599 N N   . LEU D 1 211 ? -32.043  -9.151  31.659  1.00 45.93  ? 271 LEU D N   1 
ATOM   14600 C CA  . LEU D 1 211 ? -33.013  -8.071  31.978  1.00 50.08  ? 271 LEU D CA  1 
ATOM   14601 C C   . LEU D 1 211 ? -33.082  -7.077  30.821  1.00 49.18  ? 271 LEU D C   1 
ATOM   14602 O O   . LEU D 1 211 ? -32.220  -6.216  30.685  1.00 50.44  ? 271 LEU D O   1 
ATOM   14603 C CB  . LEU D 1 211 ? -32.617  -7.380  33.289  1.00 50.21  ? 271 LEU D CB  1 
ATOM   14604 C CG  . LEU D 1 211 ? -33.305  -6.034  33.570  1.00 50.93  ? 271 LEU D CG  1 
ATOM   14605 C CD1 . LEU D 1 211 ? -34.793  -6.176  33.625  1.00 56.36  ? 271 LEU D CD1 1 
ATOM   14606 C CD2 . LEU D 1 211 ? -32.861  -5.407  34.871  1.00 48.91  ? 271 LEU D CD2 1 
ATOM   14607 N N   . PRO D 1 212 ? -34.110  -7.144  29.956  1.00 43.18  ? 272 PRO D N   1 
ATOM   14608 C CA  . PRO D 1 212 ? -34.213  -6.213  28.845  1.00 43.33  ? 272 PRO D CA  1 
ATOM   14609 C C   . PRO D 1 212 ? -34.732  -4.872  29.350  1.00 39.44  ? 272 PRO D C   1 
ATOM   14610 O O   . PRO D 1 212 ? -35.741  -4.879  29.963  1.00 43.24  ? 272 PRO D O   1 
ATOM   14611 C CB  . PRO D 1 212 ? -35.216  -6.869  27.872  1.00 44.95  ? 272 PRO D CB  1 
ATOM   14612 C CG  . PRO D 1 212 ? -35.707  -8.135  28.550  1.00 43.48  ? 272 PRO D CG  1 
ATOM   14613 C CD  . PRO D 1 212 ? -35.214  -8.105  29.986  1.00 42.94  ? 272 PRO D CD  1 
ATOM   14614 N N   . ILE D 1 213 ? -34.027  -3.784  29.080  1.00 39.34  ? 273 ILE D N   1 
ATOM   14615 C CA  . ILE D 1 213 ? -34.448  -2.425  29.531  1.00 46.79  ? 273 ILE D CA  1 
ATOM   14616 C C   . ILE D 1 213 ? -34.586  -1.483  28.340  1.00 45.03  ? 273 ILE D C   1 
ATOM   14617 O O   . ILE D 1 213 ? -33.792  -1.586  27.417  1.00 55.92  ? 273 ILE D O   1 
ATOM   14618 C CB  . ILE D 1 213 ? -33.456  -1.882  30.579  1.00 46.78  ? 273 ILE D CB  1 
ATOM   14619 C CG1 . ILE D 1 213 ? -33.400  -2.841  31.776  1.00 42.80  ? 273 ILE D CG1 1 
ATOM   14620 C CG2 . ILE D 1 213 ? -33.811  -0.440  30.968  1.00 44.78  ? 273 ILE D CG2 1 
ATOM   14621 C CD1 . ILE D 1 213 ? -32.411  -2.469  32.854  1.00 46.65  ? 273 ILE D CD1 1 
ATOM   14622 N N   . THR D 1 214 ? -35.542  -0.572  28.389  1.00 40.89  ? 274 THR D N   1 
ATOM   14623 C CA  . THR D 1 214 ? -35.629  0.558   27.443  1.00 42.49  ? 274 THR D CA  1 
ATOM   14624 C C   . THR D 1 214 ? -35.659  1.848   28.258  1.00 44.97  ? 274 THR D C   1 
ATOM   14625 O O   . THR D 1 214 ? -36.479  1.938   29.189  1.00 45.07  ? 274 THR D O   1 
ATOM   14626 C CB  . THR D 1 214 ? -36.881  0.454   26.555  1.00 49.40  ? 274 THR D CB  1 
ATOM   14627 O OG1 . THR D 1 214 ? -36.814  -0.743  25.776  1.00 38.99  ? 274 THR D OG1 1 
ATOM   14628 C CG2 . THR D 1 214 ? -37.071  1.686   25.676  1.00 50.34  ? 274 THR D CG2 1 
ATOM   14629 N N   . ILE D 1 215 ? -34.846  2.821   27.893  1.00 45.29  ? 275 ILE D N   1 
ATOM   14630 C CA  . ILE D 1 215 ? -34.893  4.173   28.514  1.00 50.82  ? 275 ILE D CA  1 
ATOM   14631 C C   . ILE D 1 215 ? -35.726  5.072   27.601  1.00 53.85  ? 275 ILE D C   1 
ATOM   14632 O O   . ILE D 1 215 ? -35.222  5.404   26.527  1.00 52.51  ? 275 ILE D O   1 
ATOM   14633 C CB  . ILE D 1 215 ? -33.465  4.718   28.656  1.00 58.32  ? 275 ILE D CB  1 
ATOM   14634 C CG1 . ILE D 1 215 ? -32.545  3.788   29.455  1.00 55.77  ? 275 ILE D CG1 1 
ATOM   14635 C CG2 . ILE D 1 215 ? -33.475  6.154   29.163  1.00 62.85  ? 275 ILE D CG2 1 
ATOM   14636 C CD1 . ILE D 1 215 ? -32.794  3.774   30.937  1.00 61.24  ? 275 ILE D CD1 1 
ATOM   14637 N N   . ASP D 1 216 ? -36.944  5.453   27.991  1.00 58.43  ? 276 ASP D N   1 
ATOM   14638 C CA  . ASP D 1 216 ? -37.804  6.361   27.173  1.00 58.78  ? 276 ASP D CA  1 
ATOM   14639 C C   . ASP D 1 216 ? -37.534  7.805   27.590  1.00 57.80  ? 276 ASP D C   1 
ATOM   14640 O O   . ASP D 1 216 ? -37.820  8.164   28.746  1.00 61.97  ? 276 ASP D O   1 
ATOM   14641 C CB  . ASP D 1 216 ? -39.301  6.040   27.292  1.00 64.49  ? 276 ASP D CB  1 
ATOM   14642 C CG  . ASP D 1 216 ? -40.261  6.794   26.354  1.00 66.71  ? 276 ASP D CG  1 
ATOM   14643 O OD1 . ASP D 1 216 ? -39.809  7.345   25.307  1.00 68.22  ? 276 ASP D OD1 1 
ATOM   14644 O OD2 . ASP D 1 216 ? -41.479  6.795   26.647  1.00 66.06  ? 276 ASP D OD2 1 
ATOM   14645 N N   . VAL D 1 217 ? -36.999  8.611   26.683  1.00 55.31  ? 277 VAL D N   1 
ATOM   14646 C CA  . VAL D 1 217 ? -36.732  10.059  26.938  1.00 61.13  ? 277 VAL D CA  1 
ATOM   14647 C C   . VAL D 1 217 ? -37.513  10.893  25.920  1.00 60.23  ? 277 VAL D C   1 
ATOM   14648 O O   . VAL D 1 217 ? -37.261  12.108  25.818  1.00 54.46  ? 277 VAL D O   1 
ATOM   14649 C CB  . VAL D 1 217 ? -35.220  10.342  26.877  1.00 64.08  ? 277 VAL D CB  1 
ATOM   14650 C CG1 . VAL D 1 217 ? -34.507  9.701   28.063  1.00 64.72  ? 277 VAL D CG1 1 
ATOM   14651 C CG2 . VAL D 1 217 ? -34.620  9.862   25.560  1.00 71.13  ? 277 VAL D CG2 1 
ATOM   14652 N N   . GLY D 1 218 ? -38.426  10.251  25.193  1.00 59.67  ? 278 GLY D N   1 
ATOM   14653 C CA  . GLY D 1 218 ? -39.111  10.838  24.028  1.00 60.68  ? 278 GLY D CA  1 
ATOM   14654 C C   . GLY D 1 218 ? -38.585  10.258  22.730  1.00 62.13  ? 278 GLY D C   1 
ATOM   14655 O O   . GLY D 1 218 ? -37.750  9.306   22.784  1.00 69.11  ? 278 GLY D O   1 
ATOM   14656 N N   . THR D 1 219 ? -39.078  10.783  21.611  1.00 51.17  ? 279 THR D N   1 
ATOM   14657 C CA  . THR D 1 219 ? -38.712  10.344  20.248  1.00 48.16  ? 279 THR D CA  1 
ATOM   14658 C C   . THR D 1 219 ? -38.930  11.548  19.330  1.00 46.45  ? 279 THR D C   1 
ATOM   14659 O O   . THR D 1 219 ? -39.776  12.374  19.669  1.00 45.25  ? 279 THR D O   1 
ATOM   14660 C CB  . THR D 1 219 ? -39.511  9.093   19.842  1.00 47.84  ? 279 THR D CB  1 
ATOM   14661 O OG1 . THR D 1 219 ? -39.161  8.683   18.517  1.00 47.50  ? 279 THR D OG1 1 
ATOM   14662 C CG2 . THR D 1 219 ? -41.008  9.320   19.880  1.00 53.89  ? 279 THR D CG2 1 
ATOM   14663 N N   . ASN D 1 220 ? -38.205  11.626  18.217  1.00 49.37  ? 280 ASN D N   1 
ATOM   14664 C CA  . ASN D 1 220 ? -38.328  12.722  17.218  1.00 54.55  ? 280 ASN D CA  1 
ATOM   14665 C C   . ASN D 1 220 ? -39.129  12.246  15.989  1.00 62.23  ? 280 ASN D C   1 
ATOM   14666 O O   . ASN D 1 220 ? -39.550  13.121  15.143  1.00 53.33  ? 280 ASN D O   1 
ATOM   14667 C CB  . ASN D 1 220 ? -36.948  13.219  16.794  1.00 51.51  ? 280 ASN D CB  1 
ATOM   14668 C CG  . ASN D 1 220 ? -36.155  13.773  17.938  1.00 43.20  ? 280 ASN D CG  1 
ATOM   14669 O OD1 . ASN D 1 220 ? -36.704  14.346  18.871  1.00 41.99  ? 280 ASN D OD1 1 
ATOM   14670 N ND2 . ASN D 1 220 ? -34.860  13.585  17.859  1.00 50.88  ? 280 ASN D ND2 1 
ATOM   14671 N N   . ASN D 1 221 ? -39.314  10.923  15.863  1.00 59.29  ? 281 ASN D N   1 
ATOM   14672 C CA  . ASN D 1 221 ? -40.211  10.282  14.868  1.00 57.02  ? 281 ASN D CA  1 
ATOM   14673 C C   . ASN D 1 221 ? -41.612  10.919  14.948  1.00 60.16  ? 281 ASN D C   1 
ATOM   14674 O O   . ASN D 1 221 ? -42.394  10.549  15.860  1.00 61.07  ? 281 ASN D O   1 
ATOM   14675 C CB  . ASN D 1 221 ? -40.183  8.779   15.098  1.00 53.34  ? 281 ASN D CB  1 
ATOM   14676 C CG  . ASN D 1 221 ? -40.848  7.998   13.992  1.00 53.13  ? 281 ASN D CG  1 
ATOM   14677 O OD1 . ASN D 1 221 ? -40.554  6.827   13.803  1.00 58.76  ? 281 ASN D OD1 1 
ATOM   14678 N ND2 . ASN D 1 221 ? -41.796  8.598   13.300  1.00 51.92  ? 281 ASN D ND2 1 
ATOM   14679 N N   . GLU D 1 222 ? -41.920  11.840  14.025  1.00 60.21  ? 282 GLU D N   1 
ATOM   14680 C CA  . GLU D 1 222 ? -43.194  12.621  13.957  1.00 59.93  ? 282 GLU D CA  1 
ATOM   14681 C C   . GLU D 1 222 ? -44.373  11.671  13.707  1.00 55.76  ? 282 GLU D C   1 
ATOM   14682 O O   . GLU D 1 222 ? -45.460  11.941  14.226  1.00 61.00  ? 282 GLU D O   1 
ATOM   14683 C CB  . GLU D 1 222 ? -43.173  13.622  12.799  1.00 72.55  ? 282 GLU D CB  1 
ATOM   14684 C CG  . GLU D 1 222 ? -41.984  14.569  12.764  1.00 81.59  ? 282 GLU D CG  1 
ATOM   14685 C CD  . GLU D 1 222 ? -42.148  15.716  13.730  1.00 83.86  ? 282 GLU D CD  1 
ATOM   14686 O OE1 . GLU D 1 222 ? -42.931  15.554  14.680  1.00 82.69  ? 282 GLU D OE1 1 
ATOM   14687 O OE2 . GLU D 1 222 ? -41.515  16.782  13.504  1.00 82.23  ? 282 GLU D OE2 1 
ATOM   14688 N N   . LYS D 1 223 ? -44.162  10.617  12.904  1.00 64.43  ? 283 LYS D N   1 
ATOM   14689 C CA  . LYS D 1 223 ? -45.108  9.493   12.636  1.00 64.69  ? 283 LYS D CA  1 
ATOM   14690 C C   . LYS D 1 223 ? -45.583  8.871   13.960  1.00 63.64  ? 283 LYS D C   1 
ATOM   14691 O O   . LYS D 1 223 ? -46.787  8.613   14.117  1.00 80.08  ? 283 LYS D O   1 
ATOM   14692 C CB  . LYS D 1 223 ? -44.458  8.413   11.750  1.00 63.11  ? 283 LYS D CB  1 
ATOM   14693 C CG  . LYS D 1 223 ? -44.981  8.290   10.324  1.00 70.18  ? 283 LYS D CG  1 
ATOM   14694 C CD  . LYS D 1 223 ? -45.142  6.830   9.872   1.00 80.74  ? 283 LYS D CD  1 
ATOM   14695 C CE  . LYS D 1 223 ? -46.147  6.041   10.701  1.00 84.93  ? 283 LYS D CE  1 
ATOM   14696 N NZ  . LYS D 1 223 ? -46.834  5.002   9.890   1.00 94.80  ? 283 LYS D NZ  1 
ATOM   14697 N N   . LEU D 1 224 ? -44.675  8.645   14.901  1.00 56.94  ? 284 LEU D N   1 
ATOM   14698 C CA  . LEU D 1 224 ? -44.974  7.938   16.167  1.00 55.32  ? 284 LEU D CA  1 
ATOM   14699 C C   . LEU D 1 224 ? -45.582  8.906   17.183  1.00 50.93  ? 284 LEU D C   1 
ATOM   14700 O O   . LEU D 1 224 ? -46.380  8.452   17.994  1.00 51.11  ? 284 LEU D O   1 
ATOM   14701 C CB  . LEU D 1 224 ? -43.683  7.315   16.693  1.00 58.21  ? 284 LEU D CB  1 
ATOM   14702 C CG  . LEU D 1 224 ? -43.196  6.060   15.982  1.00 53.56  ? 284 LEU D CG  1 
ATOM   14703 C CD1 . LEU D 1 224 ? -42.055  5.454   16.782  1.00 62.31  ? 284 LEU D CD1 1 
ATOM   14704 C CD2 . LEU D 1 224 ? -44.300  5.039   15.763  1.00 56.42  ? 284 LEU D CD2 1 
ATOM   14705 N N   . LEU D 1 225 ? -45.206  10.183  17.166  1.00 57.61  ? 285 LEU D N   1 
ATOM   14706 C CA  . LEU D 1 225 ? -45.833  11.216  18.043  1.00 60.37  ? 285 LEU D CA  1 
ATOM   14707 C C   . LEU D 1 225 ? -47.328  11.314  17.722  1.00 57.84  ? 285 LEU D C   1 
ATOM   14708 O O   . LEU D 1 225 ? -48.110  11.472  18.660  1.00 68.46  ? 285 LEU D O   1 
ATOM   14709 C CB  . LEU D 1 225 ? -45.142  12.571  17.879  1.00 58.71  ? 285 LEU D CB  1 
ATOM   14710 C CG  . LEU D 1 225 ? -43.778  12.665  18.557  1.00 60.09  ? 285 LEU D CG  1 
ATOM   14711 C CD1 . LEU D 1 225 ? -43.152  14.027  18.332  1.00 65.64  ? 285 LEU D CD1 1 
ATOM   14712 C CD2 . LEU D 1 225 ? -43.868  12.345  20.040  1.00 59.75  ? 285 LEU D CD2 1 
ATOM   14713 N N   . ASN D 1 226 ? -47.704  11.166  16.454  1.00 54.94  ? 286 ASN D N   1 
ATOM   14714 C CA  . ASN D 1 226 ? -49.091  11.368  15.966  1.00 54.59  ? 286 ASN D CA  1 
ATOM   14715 C C   . ASN D 1 226 ? -49.810  10.033  15.838  1.00 48.72  ? 286 ASN D C   1 
ATOM   14716 O O   . ASN D 1 226 ? -50.994  10.075  15.597  1.00 50.00  ? 286 ASN D O   1 
ATOM   14717 C CB  . ASN D 1 226 ? -49.099  12.122  14.632  1.00 55.47  ? 286 ASN D CB  1 
ATOM   14718 C CG  . ASN D 1 226 ? -48.661  13.559  14.803  1.00 53.47  ? 286 ASN D CG  1 
ATOM   14719 O OD1 . ASN D 1 226 ? -47.761  14.039  14.134  1.00 55.19  ? 286 ASN D OD1 1 
ATOM   14720 N ND2 . ASN D 1 226 ? -49.294  14.253  15.725  1.00 54.82  ? 286 ASN D ND2 1 
ATOM   14721 N N   . ASP D 1 227 ? -49.108  8.909   15.957  1.00 57.93  ? 287 ASP D N   1 
ATOM   14722 C CA  . ASP D 1 227 ? -49.711  7.546   15.977  1.00 66.08  ? 287 ASP D CA  1 
ATOM   14723 C C   . ASP D 1 227 ? -50.340  7.360   17.363  1.00 61.74  ? 287 ASP D C   1 
ATOM   14724 O O   . ASP D 1 227 ? -49.651  7.620   18.359  1.00 62.28  ? 287 ASP D O   1 
ATOM   14725 C CB  . ASP D 1 227 ? -48.686  6.451   15.644  1.00 66.67  ? 287 ASP D CB  1 
ATOM   14726 C CG  . ASP D 1 227 ? -49.223  5.023   15.574  1.00 69.03  ? 287 ASP D CG  1 
ATOM   14727 O OD1 . ASP D 1 227 ? -50.264  4.731   16.190  1.00 67.65  ? 287 ASP D OD1 1 
ATOM   14728 O OD2 . ASP D 1 227 ? -48.571  4.189   14.923  1.00 77.25  ? 287 ASP D OD2 1 
ATOM   14729 N N   . GLU D 1 228 ? -51.606  6.945   17.409  1.00 64.78  ? 288 GLU D N   1 
ATOM   14730 C CA  . GLU D 1 228 ? -52.405  6.818   18.651  1.00 64.21  ? 288 GLU D CA  1 
ATOM   14731 C C   . GLU D 1 228 ? -52.056  5.521   19.391  1.00 59.68  ? 288 GLU D C   1 
ATOM   14732 O O   . GLU D 1 228 ? -52.544  5.398   20.496  1.00 56.13  ? 288 GLU D O   1 
ATOM   14733 C CB  . GLU D 1 228 ? -53.897  6.873   18.315  1.00 72.99  ? 288 GLU D CB  1 
ATOM   14734 C CG  . GLU D 1 228 ? -54.435  5.611   17.635  1.00 76.03  ? 288 GLU D CG  1 
ATOM   14735 C CD  . GLU D 1 228 ? -55.873  5.680   17.144  1.00 74.64  ? 288 GLU D CD  1 
ATOM   14736 O OE1 . GLU D 1 228 ? -56.616  6.581   17.593  1.00 76.32  ? 288 GLU D OE1 1 
ATOM   14737 O OE2 . GLU D 1 228 ? -56.251  4.837   16.310  1.00 79.73  ? 288 GLU D OE2 1 
ATOM   14738 N N   . PHE D 1 229 ? -51.268  4.592   18.821  1.00 58.79  ? 289 PHE D N   1 
ATOM   14739 C CA  . PHE D 1 229 ? -50.852  3.334   19.520  1.00 68.41  ? 289 PHE D CA  1 
ATOM   14740 C C   . PHE D 1 229 ? -49.402  3.390   20.023  1.00 68.56  ? 289 PHE D C   1 
ATOM   14741 O O   . PHE D 1 229 ? -48.923  2.382   20.590  1.00 59.28  ? 289 PHE D O   1 
ATOM   14742 C CB  . PHE D 1 229 ? -51.046  2.107   18.630  1.00 66.38  ? 289 PHE D CB  1 
ATOM   14743 C CG  . PHE D 1 229 ? -52.491  1.891   18.278  1.00 69.07  ? 289 PHE D CG  1 
ATOM   14744 C CD1 . PHE D 1 229 ? -53.449  1.938   19.281  1.00 67.45  ? 289 PHE D CD1 1 
ATOM   14745 C CD2 . PHE D 1 229 ? -52.900  1.702   16.962  1.00 70.94  ? 289 PHE D CD2 1 
ATOM   14746 C CE1 . PHE D 1 229 ? -54.791  1.780   18.977  1.00 70.19  ? 289 PHE D CE1 1 
ATOM   14747 C CE2 . PHE D 1 229 ? -54.244  1.559   16.663  1.00 75.36  ? 289 PHE D CE2 1 
ATOM   14748 C CZ  . PHE D 1 229 ? -55.187  1.592   17.670  1.00 71.64  ? 289 PHE D CZ  1 
ATOM   14749 N N   . TYR D 1 230 ? -48.717  4.524   19.850  1.00 65.04  ? 290 TYR D N   1 
ATOM   14750 C CA  . TYR D 1 230 ? -47.336  4.688   20.360  1.00 61.07  ? 290 TYR D CA  1 
ATOM   14751 C C   . TYR D 1 230 ? -47.444  4.558   21.874  1.00 59.30  ? 290 TYR D C   1 
ATOM   14752 O O   . TYR D 1 230 ? -48.329  5.200   22.471  1.00 55.70  ? 290 TYR D O   1 
ATOM   14753 C CB  . TYR D 1 230 ? -46.662  5.981   19.871  1.00 63.06  ? 290 TYR D CB  1 
ATOM   14754 C CG  . TYR D 1 230 ? -45.278  6.253   20.427  1.00 57.17  ? 290 TYR D CG  1 
ATOM   14755 C CD1 . TYR D 1 230 ? -44.211  5.398   20.212  1.00 55.50  ? 290 TYR D CD1 1 
ATOM   14756 C CD2 . TYR D 1 230 ? -45.037  7.380   21.193  1.00 58.94  ? 290 TYR D CD2 1 
ATOM   14757 C CE1 . TYR D 1 230 ? -42.954  5.658   20.747  1.00 59.59  ? 290 TYR D CE1 1 
ATOM   14758 C CE2 . TYR D 1 230 ? -43.792  7.657   21.733  1.00 56.68  ? 290 TYR D CE2 1 
ATOM   14759 C CZ  . TYR D 1 230 ? -42.737  6.798   21.511  1.00 57.78  ? 290 TYR D CZ  1 
ATOM   14760 O OH  . TYR D 1 230 ? -41.530  7.120   22.088  1.00 63.31  ? 290 TYR D OH  1 
ATOM   14761 N N   . ILE D 1 231 ? -46.566  3.724   22.428  1.00 58.88  ? 291 ILE D N   1 
ATOM   14762 C CA  . ILE D 1 231 ? -46.547  3.288   23.852  1.00 53.47  ? 291 ILE D CA  1 
ATOM   14763 C C   . ILE D 1 231 ? -45.622  4.200   24.652  1.00 44.52  ? 291 ILE D C   1 
ATOM   14764 O O   . ILE D 1 231 ? -45.528  3.980   25.846  1.00 56.96  ? 291 ILE D O   1 
ATOM   14765 C CB  . ILE D 1 231 ? -46.097  1.811   23.968  1.00 50.99  ? 291 ILE D CB  1 
ATOM   14766 C CG1 . ILE D 1 231 ? -44.626  1.634   23.564  1.00 49.85  ? 291 ILE D CG1 1 
ATOM   14767 C CG2 . ILE D 1 231 ? -47.023  0.912   23.159  1.00 49.71  ? 291 ILE D CG2 1 
ATOM   14768 C CD1 . ILE D 1 231 ? -44.184  0.200   23.430  1.00 47.88  ? 291 ILE D CD1 1 
ATOM   14769 N N   . GLY D 1 232 ? -44.929  5.148   24.037  1.00 40.91  ? 292 GLY D N   1 
ATOM   14770 C CA  . GLY D 1 232 ? -43.978  6.022   24.765  1.00 46.61  ? 292 GLY D CA  1 
ATOM   14771 C C   . GLY D 1 232 ? -44.553  7.395   25.116  1.00 42.09  ? 292 GLY D C   1 
ATOM   14772 O O   . GLY D 1 232 ? -45.690  7.666   24.784  1.00 42.80  ? 292 GLY D O   1 
ATOM   14773 N N   . LEU D 1 233 ? -43.749  8.240   25.740  1.00 44.10  ? 293 LEU D N   1 
ATOM   14774 C CA  . LEU D 1 233 ? -44.086  9.656   26.046  1.00 50.60  ? 293 LEU D CA  1 
ATOM   14775 C C   . LEU D 1 233 ? -44.264  10.396  24.721  1.00 48.04  ? 293 LEU D C   1 
ATOM   14776 O O   . LEU D 1 233 ? -43.323  10.331  23.927  1.00 53.18  ? 293 LEU D O   1 
ATOM   14777 C CB  . LEU D 1 233 ? -42.956  10.296  26.864  1.00 50.51  ? 293 LEU D CB  1 
ATOM   14778 C CG  . LEU D 1 233 ? -42.474  9.521   28.101  1.00 47.64  ? 293 LEU D CG  1 
ATOM   14779 C CD1 . LEU D 1 233 ? -41.206  10.148  28.651  1.00 51.94  ? 293 LEU D CD1 1 
ATOM   14780 C CD2 . LEU D 1 233 ? -43.520  9.464   29.204  1.00 44.09  ? 293 LEU D CD2 1 
ATOM   14781 N N   . ARG D 1 234 ? -45.415  11.049  24.508  1.00 52.90  ? 294 ARG D N   1 
ATOM   14782 C CA  . ARG D 1 234 ? -45.688  11.907  23.316  1.00 54.52  ? 294 ARG D CA  1 
ATOM   14783 C C   . ARG D 1 234 ? -44.945  13.237  23.464  1.00 60.30  ? 294 ARG D C   1 
ATOM   14784 O O   . ARG D 1 234 ? -45.640  14.294  23.624  1.00 56.59  ? 294 ARG D O   1 
ATOM   14785 C CB  . ARG D 1 234 ? -47.176  12.222  23.102  1.00 50.96  ? 294 ARG D CB  1 
ATOM   14786 C CG  . ARG D 1 234 ? -47.929  11.086  22.442  1.00 55.44  ? 294 ARG D CG  1 
ATOM   14787 C CD  . ARG D 1 234 ? -49.224  11.419  21.698  1.00 56.01  ? 294 ARG D CD  1 
ATOM   14788 N NE  . ARG D 1 234 ? -49.506  10.256  20.865  1.00 54.77  ? 294 ARG D NE  1 
ATOM   14789 C CZ  . ARG D 1 234 ? -49.797  9.052   21.358  1.00 64.14  ? 294 ARG D CZ  1 
ATOM   14790 N NH1 . ARG D 1 234 ? -49.900  8.848   22.667  1.00 70.42  ? 294 ARG D NH1 1 
ATOM   14791 N NH2 . ARG D 1 234 ? -49.984  8.035   20.555  1.00 60.56  ? 294 ARG D NH2 1 
ATOM   14792 N N   . GLN D 1 235 ? -43.607  13.191  23.391  1.00 57.99  ? 295 GLN D N   1 
ATOM   14793 C CA  . GLN D 1 235 ? -42.736  14.394  23.405  1.00 65.56  ? 295 GLN D CA  1 
ATOM   14794 C C   . GLN D 1 235 ? -41.450  14.095  22.629  1.00 66.51  ? 295 GLN D C   1 
ATOM   14795 O O   . GLN D 1 235 ? -41.103  12.914  22.496  1.00 66.57  ? 295 GLN D O   1 
ATOM   14796 C CB  . GLN D 1 235 ? -42.423  14.817  24.840  1.00 61.23  ? 295 GLN D CB  1 
ATOM   14797 C CG  . GLN D 1 235 ? -41.825  13.703  25.668  1.00 57.67  ? 295 GLN D CG  1 
ATOM   14798 C CD  . GLN D 1 235 ? -41.117  14.211  26.892  1.00 62.29  ? 295 GLN D CD  1 
ATOM   14799 O OE1 . GLN D 1 235 ? -41.642  14.116  28.003  1.00 64.41  ? 295 GLN D OE1 1 
ATOM   14800 N NE2 . GLN D 1 235 ? -39.896  14.697  26.693  1.00 62.36  ? 295 GLN D NE2 1 
ATOM   14801 N N   . LYS D 1 236 ? -40.790  15.141  22.129  1.00 68.94  ? 296 LYS D N   1 
ATOM   14802 C CA  . LYS D 1 236 ? -39.531  15.046  21.353  1.00 71.74  ? 296 LYS D CA  1 
ATOM   14803 C C   . LYS D 1 236 ? -38.426  14.725  22.372  1.00 73.97  ? 296 LYS D C   1 
ATOM   14804 O O   . LYS D 1 236 ? -38.656  14.961  23.596  1.00 91.90  ? 296 LYS D O   1 
ATOM   14805 C CB  . LYS D 1 236 ? -39.349  16.378  20.600  1.00 76.13  ? 296 LYS D CB  1 
ATOM   14806 C CG  . LYS D 1 236 ? -38.438  16.361  19.375  1.00 95.85  ? 296 LYS D CG  1 
ATOM   14807 C CD  . LYS D 1 236 ? -37.237  17.348  19.356  1.00 104.07 ? 296 LYS D CD  1 
ATOM   14808 C CE  . LYS D 1 236 ? -36.081  16.900  20.245  1.00 119.52 ? 296 LYS D CE  1 
ATOM   14809 N NZ  . LYS D 1 236 ? -34.754  17.339  19.757  1.00 122.29 ? 296 LYS D NZ  1 
ATOM   14810 N N   . ARG D 1 237 ? -37.303  14.137  21.948  1.00 70.19  ? 297 ARG D N   1 
ATOM   14811 C CA  . ARG D 1 237 ? -36.252  13.635  22.882  1.00 63.68  ? 297 ARG D CA  1 
ATOM   14812 C C   . ARG D 1 237 ? -35.736  14.781  23.760  1.00 66.10  ? 297 ARG D C   1 
ATOM   14813 O O   . ARG D 1 237 ? -35.435  15.858  23.223  1.00 60.12  ? 297 ARG D O   1 
ATOM   14814 C CB  . ARG D 1 237 ? -35.078  13.004  22.124  1.00 59.34  ? 297 ARG D CB  1 
ATOM   14815 C CG  . ARG D 1 237 ? -35.319  11.562  21.725  1.00 59.25  ? 297 ARG D CG  1 
ATOM   14816 C CD  . ARG D 1 237 ? -34.147  10.888  21.068  1.00 58.25  ? 297 ARG D CD  1 
ATOM   14817 N NE  . ARG D 1 237 ? -34.626  9.578   20.659  1.00 57.91  ? 297 ARG D NE  1 
ATOM   14818 C CZ  . ARG D 1 237 ? -34.610  8.479   21.406  1.00 57.20  ? 297 ARG D CZ  1 
ATOM   14819 N NH1 . ARG D 1 237 ? -34.095  8.487   22.632  1.00 51.24  ? 297 ARG D NH1 1 
ATOM   14820 N NH2 . ARG D 1 237 ? -35.103  7.359   20.894  1.00 60.25  ? 297 ARG D NH2 1 
ATOM   14821 N N   . ALA D 1 238 ? -35.604  14.530  25.060  1.00 71.34  ? 298 ALA D N   1 
ATOM   14822 C CA  . ALA D 1 238 ? -34.805  15.353  25.997  1.00 66.57  ? 298 ALA D CA  1 
ATOM   14823 C C   . ALA D 1 238 ? -33.321  15.239  25.633  1.00 64.09  ? 298 ALA D C   1 
ATOM   14824 O O   . ALA D 1 238 ? -32.855  14.107  25.352  1.00 61.34  ? 298 ALA D O   1 
ATOM   14825 C CB  . ALA D 1 238 ? -35.068  14.915  27.423  1.00 66.99  ? 298 ALA D CB  1 
ATOM   14826 N N   . THR D 1 239 ? -32.613  16.373  25.676  1.00 72.56  ? 299 THR D N   1 
ATOM   14827 C CA  . THR D 1 239 ? -31.180  16.525  25.302  1.00 72.92  ? 299 THR D CA  1 
ATOM   14828 C C   . THR D 1 239 ? -30.361  17.032  26.505  1.00 73.68  ? 299 THR D C   1 
ATOM   14829 O O   . THR D 1 239 ? -30.953  17.418  27.534  1.00 75.64  ? 299 THR D O   1 
ATOM   14830 C CB  . THR D 1 239 ? -31.078  17.428  24.064  1.00 70.88  ? 299 THR D CB  1 
ATOM   14831 O OG1 . THR D 1 239 ? -31.393  18.773  24.438  1.00 67.74  ? 299 THR D OG1 1 
ATOM   14832 C CG2 . THR D 1 239 ? -31.986  16.955  22.945  1.00 70.49  ? 299 THR D CG2 1 
ATOM   14833 N N   . GLY D 1 240 ? -29.034  16.984  26.387  1.00 81.99  ? 300 GLY D N   1 
ATOM   14834 C CA  . GLY D 1 240 ? -28.073  17.570  27.345  1.00 86.19  ? 300 GLY D CA  1 
ATOM   14835 C C   . GLY D 1 240 ? -28.363  17.202  28.795  1.00 87.47  ? 300 GLY D C   1 
ATOM   14836 O O   . GLY D 1 240 ? -28.549  16.009  29.090  1.00 68.77  ? 300 GLY D O   1 
ATOM   14837 N N   . GLU D 1 241 ? -28.381  18.217  29.665  1.00 98.23  ? 301 GLU D N   1 
ATOM   14838 C CA  . GLU D 1 241 ? -28.608  18.150  31.138  1.00 90.53  ? 301 GLU D CA  1 
ATOM   14839 C C   . GLU D 1 241 ? -29.669  17.085  31.471  1.00 89.23  ? 301 GLU D C   1 
ATOM   14840 O O   . GLU D 1 241 ? -29.350  16.103  32.204  1.00 74.45  ? 301 GLU D O   1 
ATOM   14841 C CB  . GLU D 1 241 ? -29.047  19.534  31.628  1.00 97.16  ? 301 GLU D CB  1 
ATOM   14842 C CG  . GLU D 1 241 ? -28.199  20.684  31.063  1.00 106.81 ? 301 GLU D CG  1 
ATOM   14843 C CD  . GLU D 1 241 ? -28.940  21.868  30.438  1.00 101.41 ? 301 GLU D CD  1 
ATOM   14844 O OE1 . GLU D 1 241 ? -29.381  21.780  29.259  1.00 80.41  ? 301 GLU D OE1 1 
ATOM   14845 O OE2 . GLU D 1 241 ? -29.047  22.906  31.124  1.00 97.98  ? 301 GLU D OE2 1 
ATOM   14846 N N   . GLU D 1 242 ? -30.887  17.261  30.955  1.00 85.48  ? 302 GLU D N   1 
ATOM   14847 C CA  . GLU D 1 242 ? -32.066  16.452  31.356  1.00 76.94  ? 302 GLU D CA  1 
ATOM   14848 C C   . GLU D 1 242 ? -31.815  14.973  31.021  1.00 75.08  ? 302 GLU D C   1 
ATOM   14849 O O   . GLU D 1 242 ? -32.038  14.115  31.907  1.00 91.04  ? 302 GLU D O   1 
ATOM   14850 C CB  . GLU D 1 242 ? -33.352  16.972  30.707  1.00 75.70  ? 302 GLU D CB  1 
ATOM   14851 C CG  . GLU D 1 242 ? -34.584  16.560  31.503  1.00 76.46  ? 302 GLU D CG  1 
ATOM   14852 C CD  . GLU D 1 242 ? -35.913  16.640  30.782  1.00 78.74  ? 302 GLU D CD  1 
ATOM   14853 O OE1 . GLU D 1 242 ? -36.024  17.510  29.890  1.00 74.46  ? 302 GLU D OE1 1 
ATOM   14854 O OE2 . GLU D 1 242 ? -36.838  15.852  31.146  1.00 76.09  ? 302 GLU D OE2 1 
ATOM   14855 N N   . TYR D 1 243 ? -31.365  14.679  29.801  1.00 63.19  ? 303 TYR D N   1 
ATOM   14856 C CA  . TYR D 1 243 ? -31.003  13.309  29.357  1.00 68.46  ? 303 TYR D CA  1 
ATOM   14857 C C   . TYR D 1 243 ? -29.975  12.734  30.339  1.00 75.92  ? 303 TYR D C   1 
ATOM   14858 O O   . TYR D 1 243 ? -30.224  11.672  30.964  1.00 80.00  ? 303 TYR D O   1 
ATOM   14859 C CB  . TYR D 1 243 ? -30.454  13.327  27.924  1.00 72.85  ? 303 TYR D CB  1 
ATOM   14860 C CG  . TYR D 1 243 ? -30.027  11.985  27.384  1.00 69.11  ? 303 TYR D CG  1 
ATOM   14861 C CD1 . TYR D 1 243 ? -30.938  11.130  26.807  1.00 76.20  ? 303 TYR D CD1 1 
ATOM   14862 C CD2 . TYR D 1 243 ? -28.718  11.547  27.461  1.00 71.23  ? 303 TYR D CD2 1 
ATOM   14863 C CE1 . TYR D 1 243 ? -30.578  9.879   26.323  1.00 85.35  ? 303 TYR D CE1 1 
ATOM   14864 C CE2 . TYR D 1 243 ? -28.330  10.309  26.963  1.00 78.79  ? 303 TYR D CE2 1 
ATOM   14865 C CZ  . TYR D 1 243 ? -29.267  9.455   26.407  1.00 84.08  ? 303 TYR D CZ  1 
ATOM   14866 O OH  . TYR D 1 243 ? -28.901  8.228   25.920  1.00 76.99  ? 303 TYR D OH  1 
ATOM   14867 N N   . ASP D 1 244 ? -28.857  13.444  30.494  1.00 75.20  ? 304 ASP D N   1 
ATOM   14868 C CA  . ASP D 1 244 ? -27.654  12.947  31.203  1.00 79.47  ? 304 ASP D CA  1 
ATOM   14869 C C   . ASP D 1 244 ? -28.033  12.455  32.603  1.00 78.05  ? 304 ASP D C   1 
ATOM   14870 O O   . ASP D 1 244 ? -27.576  11.360  32.976  1.00 81.57  ? 304 ASP D O   1 
ATOM   14871 C CB  . ASP D 1 244 ? -26.566  14.022  31.274  1.00 86.66  ? 304 ASP D CB  1 
ATOM   14872 C CG  . ASP D 1 244 ? -25.850  14.289  29.962  1.00 81.74  ? 304 ASP D CG  1 
ATOM   14873 O OD1 . ASP D 1 244 ? -25.705  13.346  29.145  1.00 73.66  ? 304 ASP D OD1 1 
ATOM   14874 O OD2 . ASP D 1 244 ? -25.430  15.438  29.777  1.00 85.39  ? 304 ASP D OD2 1 
ATOM   14875 N N   . GLU D 1 245 ? -28.814  13.243  33.347  1.00 74.74  ? 305 GLU D N   1 
ATOM   14876 C CA  . GLU D 1 245 ? -29.177  12.933  34.757  1.00 81.32  ? 305 GLU D CA  1 
ATOM   14877 C C   . GLU D 1 245 ? -29.898  11.593  34.861  1.00 76.35  ? 305 GLU D C   1 
ATOM   14878 O O   . GLU D 1 245 ? -29.586  10.827  35.796  1.00 57.92  ? 305 GLU D O   1 
ATOM   14879 C CB  . GLU D 1 245 ? -30.008  14.045  35.367  1.00 84.87  ? 305 GLU D CB  1 
ATOM   14880 C CG  . GLU D 1 245 ? -29.079  15.076  35.964  1.00 98.72  ? 305 GLU D CG  1 
ATOM   14881 C CD  . GLU D 1 245 ? -29.778  16.310  36.459  1.00 114.56 ? 305 GLU D CD  1 
ATOM   14882 O OE1 . GLU D 1 245 ? -30.954  16.167  36.895  1.00 129.32 ? 305 GLU D OE1 1 
ATOM   14883 O OE2 . GLU D 1 245 ? -29.143  17.388  36.388  1.00 105.35 ? 305 GLU D OE2 1 
ATOM   14884 N N   . LEU D 1 246 ? -30.832  11.338  33.950  1.00 83.89  ? 306 LEU D N   1 
ATOM   14885 C CA  . LEU D 1 246 ? -31.541  10.037  33.927  1.00 84.05  ? 306 LEU D CA  1 
ATOM   14886 C C   . LEU D 1 246 ? -30.506  8.922   33.763  1.00 82.99  ? 306 LEU D C   1 
ATOM   14887 O O   . LEU D 1 246 ? -30.524  7.957   34.559  1.00 81.64  ? 306 LEU D O   1 
ATOM   14888 C CB  . LEU D 1 246 ? -32.578  9.997   32.805  1.00 71.68  ? 306 LEU D CB  1 
ATOM   14889 C CG  . LEU D 1 246 ? -33.559  8.838   32.932  1.00 67.52  ? 306 LEU D CG  1 
ATOM   14890 C CD1 . LEU D 1 246 ? -34.461  9.075   34.125  1.00 68.14  ? 306 LEU D CD1 1 
ATOM   14891 C CD2 . LEU D 1 246 ? -34.360  8.662   31.657  1.00 73.92  ? 306 LEU D CD2 1 
ATOM   14892 N N   . ILE D 1 247 ? -29.600  9.084   32.803  1.00 76.19  ? 307 ILE D N   1 
ATOM   14893 C CA  . ILE D 1 247 ? -28.606  8.021   32.494  1.00 80.40  ? 307 ILE D CA  1 
ATOM   14894 C C   . ILE D 1 247 ? -27.750  7.758   33.739  1.00 81.03  ? 307 ILE D C   1 
ATOM   14895 O O   . ILE D 1 247 ? -27.593  6.577   34.113  1.00 76.77  ? 307 ILE D O   1 
ATOM   14896 C CB  . ILE D 1 247 ? -27.756  8.399   31.276  1.00 77.81  ? 307 ILE D CB  1 
ATOM   14897 C CG1 . ILE D 1 247 ? -28.625  8.601   30.038  1.00 89.26  ? 307 ILE D CG1 1 
ATOM   14898 C CG2 . ILE D 1 247 ? -26.681  7.355   31.049  1.00 77.39  ? 307 ILE D CG2 1 
ATOM   14899 C CD1 . ILE D 1 247 ? -29.183  7.311   29.459  1.00 99.51  ? 307 ILE D CD1 1 
ATOM   14900 N N   . GLU D 1 248 ? -27.222  8.810   34.368  1.00 78.16  ? 308 GLU D N   1 
ATOM   14901 C CA  . GLU D 1 248 ? -26.200  8.643   35.432  1.00 77.10  ? 308 GLU D CA  1 
ATOM   14902 C C   . GLU D 1 248 ? -26.914  8.109   36.676  1.00 68.12  ? 308 GLU D C   1 
ATOM   14903 O O   . GLU D 1 248 ? -26.260  7.404   37.472  1.00 73.90  ? 308 GLU D O   1 
ATOM   14904 C CB  . GLU D 1 248 ? -25.365  9.924   35.596  1.00 84.90  ? 308 GLU D CB  1 
ATOM   14905 C CG  . GLU D 1 248 ? -26.002  10.998  36.469  1.00 93.99  ? 308 GLU D CG  1 
ATOM   14906 C CD  . GLU D 1 248 ? -25.323  12.358  36.514  1.00 105.31 ? 308 GLU D CD  1 
ATOM   14907 O OE1 . GLU D 1 248 ? -24.947  12.890  35.441  1.00 103.92 ? 308 GLU D OE1 1 
ATOM   14908 O OE2 . GLU D 1 248 ? -25.207  12.909  37.628  1.00 98.92  ? 308 GLU D OE2 1 
ATOM   14909 N N   . GLU D 1 249 ? -28.221  8.371   36.791  1.00 64.69  ? 309 GLU D N   1 
ATOM   14910 C CA  . GLU D 1 249 ? -29.055  7.839   37.900  1.00 61.17  ? 309 GLU D CA  1 
ATOM   14911 C C   . GLU D 1 249 ? -29.338  6.359   37.601  1.00 57.07  ? 309 GLU D C   1 
ATOM   14912 O O   . GLU D 1 249 ? -29.303  5.536   38.545  1.00 48.41  ? 309 GLU D O   1 
ATOM   14913 C CB  . GLU D 1 249 ? -30.318  8.685   38.092  1.00 57.58  ? 309 GLU D CB  1 
ATOM   14914 C CG  . GLU D 1 249 ? -31.474  7.901   38.702  1.00 67.07  ? 309 GLU D CG  1 
ATOM   14915 C CD  . GLU D 1 249 ? -32.679  8.688   39.193  1.00 70.24  ? 309 GLU D CD  1 
ATOM   14916 O OE1 . GLU D 1 249 ? -32.788  9.893   38.817  1.00 79.86  ? 309 GLU D OE1 1 
ATOM   14917 O OE2 . GLU D 1 249 ? -33.534  8.079   39.920  1.00 71.69  ? 309 GLU D OE2 1 
ATOM   14918 N N   . PHE D 1 250 ? -29.624  6.046   36.333  1.00 61.27  ? 310 PHE D N   1 
ATOM   14919 C CA  . PHE D 1 250 ? -29.824  4.661   35.835  1.00 59.12  ? 310 PHE D CA  1 
ATOM   14920 C C   . PHE D 1 250 ? -28.565  3.853   36.173  1.00 61.01  ? 310 PHE D C   1 
ATOM   14921 O O   . PHE D 1 250 ? -28.661  2.788   36.833  1.00 55.41  ? 310 PHE D O   1 
ATOM   14922 C CB  . PHE D 1 250 ? -30.157  4.632   34.337  1.00 52.77  ? 310 PHE D CB  1 
ATOM   14923 C CG  . PHE D 1 250 ? -30.218  3.233   33.787  1.00 59.77  ? 310 PHE D CG  1 
ATOM   14924 C CD1 . PHE D 1 250 ? -31.265  2.382   34.106  1.00 59.70  ? 310 PHE D CD1 1 
ATOM   14925 C CD2 . PHE D 1 250 ? -29.200  2.732   32.988  1.00 67.33  ? 310 PHE D CD2 1 
ATOM   14926 C CE1 . PHE D 1 250 ? -31.309  1.087   33.611  1.00 61.16  ? 310 PHE D CE1 1 
ATOM   14927 C CE2 . PHE D 1 250 ? -29.247  1.432   32.493  1.00 67.00  ? 310 PHE D CE2 1 
ATOM   14928 C CZ  . PHE D 1 250 ? -30.296  0.606   32.813  1.00 61.56  ? 310 PHE D CZ  1 
ATOM   14929 N N   . MET D 1 251 ? -27.403  4.392   35.785  1.00 63.96  ? 311 MET D N   1 
ATOM   14930 C CA  . MET D 1 251 ? -26.083  3.702   35.902  1.00 59.54  ? 311 MET D CA  1 
ATOM   14931 C C   . MET D 1 251 ? -25.727  3.566   37.393  1.00 56.86  ? 311 MET D C   1 
ATOM   14932 O O   . MET D 1 251 ? -25.235  2.508   37.798  1.00 50.19  ? 311 MET D O   1 
ATOM   14933 C CB  . MET D 1 251 ? -24.990  4.466   35.139  1.00 61.55  ? 311 MET D CB  1 
ATOM   14934 C CG  . MET D 1 251 ? -25.008  4.279   33.608  1.00 61.26  ? 311 MET D CG  1 
ATOM   14935 S SD  . MET D 1 251 ? -25.144  2.517   32.953  1.00 63.80  ? 311 MET D SD  1 
ATOM   14936 C CE  . MET D 1 251 ? -23.432  1.991   32.983  1.00 59.77  ? 311 MET D CE  1 
ATOM   14937 N N   . SER D 1 252 ? -26.017  4.589   38.199  1.00 55.06  ? 312 SER D N   1 
ATOM   14938 C CA  . SER D 1 252 ? -25.949  4.502   39.677  1.00 55.86  ? 312 SER D CA  1 
ATOM   14939 C C   . SER D 1 252 ? -26.783  3.304   40.153  1.00 60.72  ? 312 SER D C   1 
ATOM   14940 O O   . SER D 1 252 ? -26.215  2.394   40.780  1.00 56.33  ? 312 SER D O   1 
ATOM   14941 C CB  . SER D 1 252 ? -26.417  5.770   40.311  1.00 56.92  ? 312 SER D CB  1 
ATOM   14942 O OG  . SER D 1 252 ? -25.881  5.844   41.622  1.00 64.70  ? 312 SER D OG  1 
ATOM   14943 N N   . ALA D 1 253 ? -28.079  3.325   39.830  1.00 54.66  ? 313 ALA D N   1 
ATOM   14944 C CA  . ALA D 1 253 ? -29.120  2.423   40.362  1.00 53.17  ? 313 ALA D CA  1 
ATOM   14945 C C   . ALA D 1 253 ? -28.813  0.966   40.003  1.00 52.05  ? 313 ALA D C   1 
ATOM   14946 O O   . ALA D 1 253 ? -29.096  0.049   40.798  1.00 53.26  ? 313 ALA D O   1 
ATOM   14947 C CB  . ALA D 1 253 ? -30.450  2.847   39.808  1.00 57.89  ? 313 ALA D CB  1 
ATOM   14948 N N   . VAL D 1 254 ? -28.299  0.745   38.809  1.00 49.18  ? 314 VAL D N   1 
ATOM   14949 C CA  . VAL D 1 254 ? -27.968  -0.615  38.318  1.00 53.87  ? 314 VAL D CA  1 
ATOM   14950 C C   . VAL D 1 254 ? -26.879  -1.165  39.234  1.00 54.51  ? 314 VAL D C   1 
ATOM   14951 O O   . VAL D 1 254 ? -26.981  -2.334  39.640  1.00 42.97  ? 314 VAL D O   1 
ATOM   14952 C CB  . VAL D 1 254 ? -27.530  -0.566  36.845  1.00 59.81  ? 314 VAL D CB  1 
ATOM   14953 C CG1 . VAL D 1 254 ? -26.997  -1.919  36.374  1.00 67.19  ? 314 VAL D CG1 1 
ATOM   14954 C CG2 . VAL D 1 254 ? -28.665  -0.068  35.941  1.00 64.57  ? 314 VAL D CG2 1 
ATOM   14955 N N   . LYS D 1 255 ? -25.894  -0.315  39.545  1.00 63.32  ? 315 LYS D N   1 
ATOM   14956 C CA  . LYS D 1 255 ? -24.689  -0.621  40.356  1.00 65.60  ? 315 LYS D CA  1 
ATOM   14957 C C   . LYS D 1 255 ? -25.136  -1.070  41.744  1.00 58.52  ? 315 LYS D C   1 
ATOM   14958 O O   . LYS D 1 255 ? -24.634  -2.126  42.176  1.00 49.12  ? 315 LYS D O   1 
ATOM   14959 C CB  . LYS D 1 255 ? -23.806  0.636   40.463  1.00 76.45  ? 315 LYS D CB  1 
ATOM   14960 C CG  . LYS D 1 255 ? -22.407  0.476   41.036  1.00 82.93  ? 315 LYS D CG  1 
ATOM   14961 C CD  . LYS D 1 255 ? -21.301  0.462   40.000  1.00 82.32  ? 315 LYS D CD  1 
ATOM   14962 C CE  . LYS D 1 255 ? -19.999  1.027   40.523  1.00 78.50  ? 315 LYS D CE  1 
ATOM   14963 N NZ  . LYS D 1 255 ? -19.315  0.079   41.428  1.00 80.24  ? 315 LYS D NZ  1 
ATOM   14964 N N   . GLN D 1 256 ? -25.999  -0.260  42.393  1.00 63.82  ? 316 GLN D N   1 
ATOM   14965 C CA  . GLN D 1 256 ? -26.497  -0.454  43.788  1.00 62.39  ? 316 GLN D CA  1 
ATOM   14966 C C   . GLN D 1 256 ? -27.258  -1.779  43.838  1.00 56.92  ? 316 GLN D C   1 
ATOM   14967 O O   . GLN D 1 256 ? -27.014  -2.565  44.741  1.00 51.49  ? 316 GLN D O   1 
ATOM   14968 C CB  . GLN D 1 256 ? -27.365  0.709   44.285  1.00 49.74  ? 316 GLN D CB  1 
ATOM   14969 C CG  . GLN D 1 256 ? -26.541  1.938   44.639  1.00 57.79  ? 316 GLN D CG  1 
ATOM   14970 C CD  . GLN D 1 256 ? -27.281  2.993   45.435  1.00 62.02  ? 316 GLN D CD  1 
ATOM   14971 O OE1 . GLN D 1 256 ? -28.019  3.827   44.903  1.00 58.44  ? 316 GLN D OE1 1 
ATOM   14972 N NE2 . GLN D 1 256 ? -27.048  3.006   46.736  1.00 63.89  ? 316 GLN D NE2 1 
ATOM   14973 N N   . PHE D 1 257 ? -28.105  -2.031  42.857  1.00 57.17  ? 317 PHE D N   1 
ATOM   14974 C CA  . PHE D 1 257 ? -29.019  -3.194  42.878  1.00 65.25  ? 317 PHE D CA  1 
ATOM   14975 C C   . PHE D 1 257 ? -28.234  -4.467  42.509  1.00 67.00  ? 317 PHE D C   1 
ATOM   14976 O O   . PHE D 1 257 ? -28.296  -5.459  43.272  1.00 65.02  ? 317 PHE D O   1 
ATOM   14977 C CB  . PHE D 1 257 ? -30.263  -2.913  42.020  1.00 76.96  ? 317 PHE D CB  1 
ATOM   14978 C CG  . PHE D 1 257 ? -31.540  -3.386  42.681  1.00 89.36  ? 317 PHE D CG  1 
ATOM   14979 C CD1 . PHE D 1 257 ? -31.989  -2.743  43.826  1.00 96.76  ? 317 PHE D CD1 1 
ATOM   14980 C CD2 . PHE D 1 257 ? -32.279  -4.465  42.197  1.00 96.59  ? 317 PHE D CD2 1 
ATOM   14981 C CE1 . PHE D 1 257 ? -33.123  -3.172  44.488  1.00 87.17  ? 317 PHE D CE1 1 
ATOM   14982 C CE2 . PHE D 1 257 ? -33.421  -4.880  42.864  1.00 91.08  ? 317 PHE D CE2 1 
ATOM   14983 C CZ  . PHE D 1 257 ? -33.824  -4.248  44.015  1.00 90.97  ? 317 PHE D CZ  1 
ATOM   14984 N N   . TYR D 1 258 ? -27.500  -4.456  41.390  1.00 63.65  ? 318 TYR D N   1 
ATOM   14985 C CA  . TYR D 1 258 ? -26.991  -5.693  40.739  1.00 61.50  ? 318 TYR D CA  1 
ATOM   14986 C C   . TYR D 1 258 ? -25.486  -5.867  41.000  1.00 55.18  ? 318 TYR D C   1 
ATOM   14987 O O   . TYR D 1 258 ? -24.971  -6.980  40.793  1.00 57.89  ? 318 TYR D O   1 
ATOM   14988 C CB  . TYR D 1 258 ? -27.406  -5.697  39.260  1.00 63.03  ? 318 TYR D CB  1 
ATOM   14989 C CG  . TYR D 1 258 ? -28.896  -5.603  39.018  1.00 64.64  ? 318 TYR D CG  1 
ATOM   14990 C CD1 . TYR D 1 258 ? -29.760  -6.559  39.538  1.00 58.06  ? 318 TYR D CD1 1 
ATOM   14991 C CD2 . TYR D 1 258 ? -29.464  -4.542  38.316  1.00 65.19  ? 318 TYR D CD2 1 
ATOM   14992 C CE1 . TYR D 1 258 ? -31.133  -6.472  39.364  1.00 58.09  ? 318 TYR D CE1 1 
ATOM   14993 C CE2 . TYR D 1 258 ? -30.837  -4.442  38.132  1.00 59.25  ? 318 TYR D CE2 1 
ATOM   14994 C CZ  . TYR D 1 258 ? -31.674  -5.418  38.650  1.00 57.29  ? 318 TYR D CZ  1 
ATOM   14995 O OH  . TYR D 1 258 ? -33.030  -5.316  38.491  1.00 58.33  ? 318 TYR D OH  1 
ATOM   14996 N N   . GLY D 1 259 ? -24.818  -4.820  41.479  1.00 52.03  ? 319 GLY D N   1 
ATOM   14997 C CA  . GLY D 1 259 ? -23.374  -4.825  41.756  1.00 58.56  ? 319 GLY D CA  1 
ATOM   14998 C C   . GLY D 1 259 ? -22.574  -4.365  40.555  1.00 68.73  ? 319 GLY D C   1 
ATOM   14999 O O   . GLY D 1 259 ? -23.157  -3.769  39.641  1.00 71.91  ? 319 GLY D O   1 
ATOM   15000 N N   . GLU D 1 260 ? -21.267  -4.631  40.561  1.00 80.07  ? 320 GLU D N   1 
ATOM   15001 C CA  . GLU D 1 260 ? -20.343  -4.144  39.508  1.00 74.79  ? 320 GLU D CA  1 
ATOM   15002 C C   . GLU D 1 260 ? -20.123  -5.250  38.461  1.00 65.50  ? 320 GLU D C   1 
ATOM   15003 O O   . GLU D 1 260 ? -20.104  -4.895  37.263  1.00 74.00  ? 320 GLU D O   1 
ATOM   15004 C CB  . GLU D 1 260 ? -19.073  -3.591  40.141  1.00 77.76  ? 320 GLU D CB  1 
ATOM   15005 C CG  . GLU D 1 260 ? -18.429  -2.532  39.265  1.00 95.00  ? 320 GLU D CG  1 
ATOM   15006 C CD  . GLU D 1 260 ? -17.586  -3.070  38.107  1.00 96.19  ? 320 GLU D CD  1 
ATOM   15007 O OE1 . GLU D 1 260 ? -17.254  -4.276  38.172  1.00 97.41  ? 320 GLU D OE1 1 
ATOM   15008 O OE2 . GLU D 1 260 ? -17.228  -2.285  37.165  1.00 78.46  ? 320 GLU D OE2 1 
ATOM   15009 N N   . LYS D 1 261 ? -20.121  -6.533  38.848  1.00 58.14  ? 321 LYS D N   1 
ATOM   15010 C CA  . LYS D 1 261 ? -19.990  -7.696  37.917  1.00 63.82  ? 321 LYS D CA  1 
ATOM   15011 C C   . LYS D 1 261 ? -21.164  -7.831  36.903  1.00 64.80  ? 321 LYS D C   1 
ATOM   15012 O O   . LYS D 1 261 ? -21.116  -8.729  36.032  1.00 61.11  ? 321 LYS D O   1 
ATOM   15013 C CB  . LYS D 1 261 ? -19.802  -8.971  38.739  1.00 67.86  ? 321 LYS D CB  1 
ATOM   15014 C CG  . LYS D 1 261 ? -18.473  -9.036  39.487  1.00 78.12  ? 321 LYS D CG  1 
ATOM   15015 C CD  . LYS D 1 261 ? -18.452  -10.140 40.515  1.00 81.39  ? 321 LYS D CD  1 
ATOM   15016 C CE  . LYS D 1 261 ? -17.307  -10.023 41.493  1.00 90.13  ? 321 LYS D CE  1 
ATOM   15017 N NZ  . LYS D 1 261 ? -17.293  -8.728  42.213  1.00 97.48  ? 321 LYS D NZ  1 
ATOM   15018 N N   . VAL D 1 262 ? -22.174  -6.967  36.941  1.00 62.62  ? 322 VAL D N   1 
ATOM   15019 C CA  . VAL D 1 262 ? -23.297  -7.027  35.965  1.00 61.52  ? 322 VAL D CA  1 
ATOM   15020 C C   . VAL D 1 262 ? -22.861  -6.386  34.640  1.00 62.03  ? 322 VAL D C   1 
ATOM   15021 O O   . VAL D 1 262 ? -22.455  -5.172  34.629  1.00 67.18  ? 322 VAL D O   1 
ATOM   15022 C CB  . VAL D 1 262 ? -24.585  -6.371  36.503  1.00 61.86  ? 322 VAL D CB  1 
ATOM   15023 C CG1 . VAL D 1 262 ? -24.480  -4.853  36.613  1.00 66.24  ? 322 VAL D CG1 1 
ATOM   15024 C CG2 . VAL D 1 262 ? -25.788  -6.768  35.659  1.00 63.94  ? 322 VAL D CG2 1 
ATOM   15025 N N   . LEU D 1 263 ? -22.989  -7.166  33.565  1.00 52.73  ? 323 LEU D N   1 
ATOM   15026 C CA  . LEU D 1 263 ? -22.758  -6.730  32.168  1.00 54.89  ? 323 LEU D CA  1 
ATOM   15027 C C   . LEU D 1 263 ? -23.894  -5.802  31.749  1.00 48.82  ? 323 LEU D C   1 
ATOM   15028 O O   . LEU D 1 263 ? -25.027  -6.197  31.896  1.00 58.08  ? 323 LEU D O   1 
ATOM   15029 C CB  . LEU D 1 263 ? -22.684  -7.969  31.271  1.00 57.49  ? 323 LEU D CB  1 
ATOM   15030 C CG  . LEU D 1 263 ? -22.450  -7.703  29.787  1.00 60.90  ? 323 LEU D CG  1 
ATOM   15031 C CD1 . LEU D 1 263 ? -21.420  -6.605  29.575  1.00 63.51  ? 323 LEU D CD1 1 
ATOM   15032 C CD2 . LEU D 1 263 ? -22.017  -8.976  29.075  1.00 66.59  ? 323 LEU D CD2 1 
ATOM   15033 N N   . ILE D 1 264 ? -23.574  -4.590  31.316  1.00 45.45  ? 324 ILE D N   1 
ATOM   15034 C CA  . ILE D 1 264 ? -24.528  -3.603  30.746  1.00 48.53  ? 324 ILE D CA  1 
ATOM   15035 C C   . ILE D 1 264 ? -24.186  -3.461  29.257  1.00 53.77  ? 324 ILE D C   1 
ATOM   15036 O O   . ILE D 1 264 ? -23.226  -2.732  28.941  1.00 50.79  ? 324 ILE D O   1 
ATOM   15037 C CB  . ILE D 1 264 ? -24.451  -2.251  31.496  1.00 50.82  ? 324 ILE D CB  1 
ATOM   15038 C CG1 . ILE D 1 264 ? -24.642  -2.424  33.007  1.00 47.86  ? 324 ILE D CG1 1 
ATOM   15039 C CG2 . ILE D 1 264 ? -25.433  -1.241  30.899  1.00 49.54  ? 324 ILE D CG2 1 
ATOM   15040 C CD1 . ILE D 1 264 ? -24.272  -1.198  33.810  1.00 49.26  ? 324 ILE D CD1 1 
ATOM   15041 N N   . GLN D 1 265 ? -24.954  -4.129  28.381  1.00 59.05  ? 325 GLN D N   1 
ATOM   15042 C CA  . GLN D 1 265 ? -24.824  -4.096  26.894  1.00 50.57  ? 325 GLN D CA  1 
ATOM   15043 C C   . GLN D 1 265 ? -25.729  -2.989  26.355  1.00 46.78  ? 325 GLN D C   1 
ATOM   15044 O O   . GLN D 1 265 ? -26.935  -3.143  26.403  1.00 51.49  ? 325 GLN D O   1 
ATOM   15045 C CB  . GLN D 1 265 ? -25.164  -5.462  26.292  1.00 50.21  ? 325 GLN D CB  1 
ATOM   15046 C CG  . GLN D 1 265 ? -25.078  -5.516  24.778  1.00 47.97  ? 325 GLN D CG  1 
ATOM   15047 C CD  . GLN D 1 265 ? -24.992  -6.960  24.348  1.00 55.09  ? 325 GLN D CD  1 
ATOM   15048 O OE1 . GLN D 1 265 ? -24.319  -7.751  24.978  1.00 60.48  ? 325 GLN D OE1 1 
ATOM   15049 N NE2 . GLN D 1 265 ? -25.718  -7.345  23.308  1.00 61.87  ? 325 GLN D NE2 1 
ATOM   15050 N N   . PHE D 1 266 ? -25.141  -1.881  25.928  1.00 49.69  ? 326 PHE D N   1 
ATOM   15051 C CA  . PHE D 1 266 ? -25.813  -0.778  25.210  1.00 53.00  ? 326 PHE D CA  1 
ATOM   15052 C C   . PHE D 1 266 ? -26.120  -1.212  23.775  1.00 57.86  ? 326 PHE D C   1 
ATOM   15053 O O   . PHE D 1 266 ? -25.230  -1.826  23.132  1.00 55.53  ? 326 PHE D O   1 
ATOM   15054 C CB  . PHE D 1 266 ? -24.942  0.471   25.191  1.00 59.05  ? 326 PHE D CB  1 
ATOM   15055 C CG  . PHE D 1 266 ? -24.712  1.055   26.552  1.00 66.37  ? 326 PHE D CG  1 
ATOM   15056 C CD1 . PHE D 1 266 ? -23.759  0.507   27.391  1.00 63.66  ? 326 PHE D CD1 1 
ATOM   15057 C CD2 . PHE D 1 266 ? -25.444  2.153   26.978  1.00 73.35  ? 326 PHE D CD2 1 
ATOM   15058 C CE1 . PHE D 1 266 ? -23.523  1.058   28.632  1.00 70.62  ? 326 PHE D CE1 1 
ATOM   15059 C CE2 . PHE D 1 266 ? -25.215  2.696   28.226  1.00 75.62  ? 326 PHE D CE2 1 
ATOM   15060 C CZ  . PHE D 1 266 ? -24.256  2.148   29.046  1.00 84.88  ? 326 PHE D CZ  1 
ATOM   15061 N N   . GLU D 1 267 ? -27.332  -0.883  23.294  1.00 54.20  ? 327 GLU D N   1 
ATOM   15062 C CA  . GLU D 1 267 ? -27.838  -1.213  21.933  1.00 52.45  ? 327 GLU D CA  1 
ATOM   15063 C C   . GLU D 1 267 ? -28.460  0.037   21.315  1.00 57.67  ? 327 GLU D C   1 
ATOM   15064 O O   . GLU D 1 267 ? -29.240  0.716   21.992  1.00 61.36  ? 327 GLU D O   1 
ATOM   15065 C CB  . GLU D 1 267 ? -28.894  -2.316  21.977  1.00 49.89  ? 327 GLU D CB  1 
ATOM   15066 C CG  . GLU D 1 267 ? -28.351  -3.688  22.290  1.00 52.69  ? 327 GLU D CG  1 
ATOM   15067 C CD  . GLU D 1 267 ? -27.565  -4.319  21.158  1.00 65.40  ? 327 GLU D CD  1 
ATOM   15068 O OE1 . GLU D 1 267 ? -27.458  -3.711  20.047  1.00 70.95  ? 327 GLU D OE1 1 
ATOM   15069 O OE2 . GLU D 1 267 ? -27.058  -5.426  21.387  1.00 67.47  ? 327 GLU D OE2 1 
ATOM   15070 N N   . ASP D 1 268 ? -28.061  0.353   20.095  1.00 65.08  ? 328 ASP D N   1 
ATOM   15071 C CA  . ASP D 1 268 ? -28.805  1.261   19.196  1.00 71.59  ? 328 ASP D CA  1 
ATOM   15072 C C   . ASP D 1 268 ? -28.995  2.640   19.855  1.00 60.15  ? 328 ASP D C   1 
ATOM   15073 O O   . ASP D 1 268 ? -30.096  3.172   19.772  1.00 49.08  ? 328 ASP D O   1 
ATOM   15074 C CB  . ASP D 1 268 ? -30.116  0.575   18.797  1.00 79.74  ? 328 ASP D CB  1 
ATOM   15075 C CG  . ASP D 1 268 ? -29.932  -0.731  18.031  1.00 80.30  ? 328 ASP D CG  1 
ATOM   15076 O OD1 . ASP D 1 268 ? -28.767  -1.099  17.715  1.00 106.74 ? 328 ASP D OD1 1 
ATOM   15077 O OD2 . ASP D 1 268 ? -30.945  -1.378  17.755  1.00 67.01  ? 328 ASP D OD2 1 
ATOM   15078 N N   . PHE D 1 269 ? -27.935  3.211   20.427  1.00 59.75  ? 329 PHE D N   1 
ATOM   15079 C CA  . PHE D 1 269 ? -27.851  4.652   20.738  1.00 59.15  ? 329 PHE D CA  1 
ATOM   15080 C C   . PHE D 1 269 ? -27.240  5.370   19.529  1.00 65.64  ? 329 PHE D C   1 
ATOM   15081 O O   . PHE D 1 269 ? -26.627  4.686   18.699  1.00 61.55  ? 329 PHE D O   1 
ATOM   15082 C CB  . PHE D 1 269 ? -26.991  4.877   21.977  1.00 56.47  ? 329 PHE D CB  1 
ATOM   15083 C CG  . PHE D 1 269 ? -27.571  4.414   23.286  1.00 57.04  ? 329 PHE D CG  1 
ATOM   15084 C CD1 . PHE D 1 269 ? -27.606  3.062   23.600  1.00 54.91  ? 329 PHE D CD1 1 
ATOM   15085 C CD2 . PHE D 1 269 ? -28.042  5.337   24.219  1.00 55.85  ? 329 PHE D CD2 1 
ATOM   15086 C CE1 . PHE D 1 269 ? -28.135  2.643   24.812  1.00 56.75  ? 329 PHE D CE1 1 
ATOM   15087 C CE2 . PHE D 1 269 ? -28.594  4.917   25.417  1.00 56.37  ? 329 PHE D CE2 1 
ATOM   15088 C CZ  . PHE D 1 269 ? -28.637  3.565   25.713  1.00 61.70  ? 329 PHE D CZ  1 
ATOM   15089 N N   . ALA D 1 270 ? -27.416  6.696   19.447  1.00 71.24  ? 330 ALA D N   1 
ATOM   15090 C CA  . ALA D 1 270 ? -26.766  7.596   18.464  1.00 67.76  ? 330 ALA D CA  1 
ATOM   15091 C C   . ALA D 1 270 ? -25.275  7.654   18.772  1.00 73.95  ? 330 ALA D C   1 
ATOM   15092 O O   . ALA D 1 270 ? -24.920  7.339   19.907  1.00 74.63  ? 330 ALA D O   1 
ATOM   15093 C CB  . ALA D 1 270 ? -27.386  8.970   18.513  1.00 68.72  ? 330 ALA D CB  1 
ATOM   15094 N N   . ASN D 1 271 ? -24.455  8.048   17.799  1.00 85.99  ? 331 ASN D N   1 
ATOM   15095 C CA  . ASN D 1 271 ? -22.983  8.196   17.968  1.00 78.86  ? 331 ASN D CA  1 
ATOM   15096 C C   . ASN D 1 271 ? -22.708  9.008   19.239  1.00 64.22  ? 331 ASN D C   1 
ATOM   15097 O O   . ASN D 1 271 ? -22.195  8.401   20.188  1.00 54.70  ? 331 ASN D O   1 
ATOM   15098 C CB  . ASN D 1 271 ? -22.213  8.704   16.737  1.00 98.07  ? 331 ASN D CB  1 
ATOM   15099 C CG  . ASN D 1 271 ? -23.017  9.440   15.684  1.00 118.56 ? 331 ASN D CG  1 
ATOM   15100 O OD1 . ASN D 1 271 ? -24.091  8.966   15.313  1.00 134.44 ? 331 ASN D OD1 1 
ATOM   15101 N ND2 . ASN D 1 271 ? -22.491  10.557  15.181  1.00 141.91 ? 331 ASN D ND2 1 
ATOM   15102 N N   . HIS D 1 272 ? -23.031  10.299  19.293  1.00 63.03  ? 332 HIS D N   1 
ATOM   15103 C CA  . HIS D 1 272 ? -22.506  11.139  20.398  1.00 66.81  ? 332 HIS D CA  1 
ATOM   15104 C C   . HIS D 1 272 ? -22.724  10.413  21.729  1.00 65.37  ? 332 HIS D C   1 
ATOM   15105 O O   . HIS D 1 272 ? -21.737  10.235  22.438  1.00 54.59  ? 332 HIS D O   1 
ATOM   15106 C CB  . HIS D 1 272 ? -23.031  12.568  20.398  1.00 82.99  ? 332 HIS D CB  1 
ATOM   15107 C CG  . HIS D 1 272 ? -21.944  13.538  20.765  1.00 102.05 ? 332 HIS D CG  1 
ATOM   15108 N ND1 . HIS D 1 272 ? -20.981  13.945  19.846  1.00 102.00 ? 332 HIS D ND1 1 
ATOM   15109 C CD2 . HIS D 1 272 ? -21.633  14.168  21.928  1.00 109.93 ? 332 HIS D CD2 1 
ATOM   15110 C CE1 . HIS D 1 272 ? -20.143  14.793  20.422  1.00 105.26 ? 332 HIS D CE1 1 
ATOM   15111 N NE2 . HIS D 1 272 ? -20.518  14.942  21.700  1.00 109.75 ? 332 HIS D NE2 1 
ATOM   15112 N N   . ASN D 1 273 ? -23.935  9.931   22.019  1.00 72.82  ? 333 ASN D N   1 
ATOM   15113 C CA  . ASN D 1 273 ? -24.262  9.227   23.301  1.00 73.75  ? 333 ASN D CA  1 
ATOM   15114 C C   . ASN D 1 273 ? -23.458  7.922   23.448  1.00 63.27  ? 333 ASN D C   1 
ATOM   15115 O O   . ASN D 1 273 ? -22.778  7.787   24.472  1.00 76.75  ? 333 ASN D O   1 
ATOM   15116 C CB  . ASN D 1 273 ? -25.751  8.879   23.447  1.00 73.89  ? 333 ASN D CB  1 
ATOM   15117 C CG  . ASN D 1 273 ? -26.650  10.089  23.502  1.00 70.69  ? 333 ASN D CG  1 
ATOM   15118 O OD1 . ASN D 1 273 ? -27.603  10.171  22.744  1.00 85.37  ? 333 ASN D OD1 1 
ATOM   15119 N ND2 . ASN D 1 273 ? -26.329  11.033  24.360  1.00 62.10  ? 333 ASN D ND2 1 
ATOM   15120 N N   . ALA D 1 274 ? -23.538  6.999   22.481  1.00 56.43  ? 334 ALA D N   1 
ATOM   15121 C CA  . ALA D 1 274 ? -22.971  5.626   22.556  1.00 60.82  ? 334 ALA D CA  1 
ATOM   15122 C C   . ALA D 1 274 ? -21.515  5.660   23.018  1.00 70.22  ? 334 ALA D C   1 
ATOM   15123 O O   . ALA D 1 274 ? -21.102  4.662   23.668  1.00 74.27  ? 334 ALA D O   1 
ATOM   15124 C CB  . ALA D 1 274 ? -23.072  4.906   21.225  1.00 63.94  ? 334 ALA D CB  1 
ATOM   15125 N N   . PHE D 1 275 ? -20.788  6.733   22.659  1.00 77.24  ? 335 PHE D N   1 
ATOM   15126 C CA  . PHE D 1 275 ? -19.356  6.986   22.994  1.00 72.71  ? 335 PHE D CA  1 
ATOM   15127 C C   . PHE D 1 275 ? -19.230  7.545   24.425  1.00 67.92  ? 335 PHE D C   1 
ATOM   15128 O O   . PHE D 1 275 ? -18.503  6.898   25.200  1.00 86.99  ? 335 PHE D O   1 
ATOM   15129 C CB  . PHE D 1 275 ? -18.662  7.863   21.939  1.00 69.53  ? 335 PHE D CB  1 
ATOM   15130 C CG  . PHE D 1 275 ? -18.369  7.176   20.620  1.00 68.91  ? 335 PHE D CG  1 
ATOM   15131 C CD1 . PHE D 1 275 ? -17.692  5.964   20.571  1.00 68.50  ? 335 PHE D CD1 1 
ATOM   15132 C CD2 . PHE D 1 275 ? -18.739  7.762   19.417  1.00 69.94  ? 335 PHE D CD2 1 
ATOM   15133 C CE1 . PHE D 1 275 ? -17.432  5.332   19.364  1.00 68.32  ? 335 PHE D CE1 1 
ATOM   15134 C CE2 . PHE D 1 275 ? -18.496  7.123   18.208  1.00 79.17  ? 335 PHE D CE2 1 
ATOM   15135 C CZ  . PHE D 1 275 ? -17.853  5.902   18.184  1.00 76.75  ? 335 PHE D CZ  1 
ATOM   15136 N N   . ASP D 1 276 ? -19.921  8.627   24.813  1.00 60.07  ? 336 ASP D N   1 
ATOM   15137 C CA  . ASP D 1 276 ? -19.836  9.155   26.209  1.00 60.29  ? 336 ASP D CA  1 
ATOM   15138 C C   . ASP D 1 276 ? -20.148  8.060   27.223  1.00 58.01  ? 336 ASP D C   1 
ATOM   15139 O O   . ASP D 1 276 ? -19.560  8.128   28.321  1.00 70.10  ? 336 ASP D O   1 
ATOM   15140 C CB  . ASP D 1 276 ? -20.759  10.342  26.476  1.00 63.23  ? 336 ASP D CB  1 
ATOM   15141 C CG  . ASP D 1 276 ? -20.518  11.450  25.480  1.00 70.14  ? 336 ASP D CG  1 
ATOM   15142 O OD1 . ASP D 1 276 ? -19.699  11.234  24.576  1.00 64.19  ? 336 ASP D OD1 1 
ATOM   15143 O OD2 . ASP D 1 276 ? -21.163  12.488  25.602  1.00 88.51  ? 336 ASP D OD2 1 
ATOM   15144 N N   . LEU D 1 277 ? -21.029  7.113   26.882  1.00 57.58  ? 337 LEU D N   1 
ATOM   15145 C CA  . LEU D 1 277 ? -21.461  6.021   27.790  1.00 65.59  ? 337 LEU D CA  1 
ATOM   15146 C C   . LEU D 1 277 ? -20.323  5.015   27.954  1.00 63.63  ? 337 LEU D C   1 
ATOM   15147 O O   . LEU D 1 277 ? -20.110  4.541   29.084  1.00 75.22  ? 337 LEU D O   1 
ATOM   15148 C CB  . LEU D 1 277 ? -22.741  5.357   27.277  1.00 68.70  ? 337 LEU D CB  1 
ATOM   15149 C CG  . LEU D 1 277 ? -23.934  6.303   27.105  1.00 74.39  ? 337 LEU D CG  1 
ATOM   15150 C CD1 . LEU D 1 277 ? -25.172  5.527   26.677  1.00 75.87  ? 337 LEU D CD1 1 
ATOM   15151 C CD2 . LEU D 1 277 ? -24.227  7.128   28.358  1.00 69.40  ? 337 LEU D CD2 1 
ATOM   15152 N N   . LEU D 1 278 ? -19.592  4.712   26.890  1.00 70.83  ? 338 LEU D N   1 
ATOM   15153 C CA  . LEU D 1 278 ? -18.419  3.795   26.963  1.00 75.26  ? 338 LEU D CA  1 
ATOM   15154 C C   . LEU D 1 278 ? -17.239  4.523   27.634  1.00 75.05  ? 338 LEU D C   1 
ATOM   15155 O O   . LEU D 1 278 ? -16.478  3.858   28.358  1.00 81.18  ? 338 LEU D O   1 
ATOM   15156 C CB  . LEU D 1 278 ? -18.072  3.310   25.553  1.00 75.83  ? 338 LEU D CB  1 
ATOM   15157 C CG  . LEU D 1 278 ? -17.896  1.807   25.390  1.00 76.47  ? 338 LEU D CG  1 
ATOM   15158 C CD1 . LEU D 1 278 ? -19.208  1.071   25.614  1.00 83.83  ? 338 LEU D CD1 1 
ATOM   15159 C CD2 . LEU D 1 278 ? -17.353  1.525   24.012  1.00 71.97  ? 338 LEU D CD2 1 
ATOM   15160 N N   . GLU D 1 279 ? -17.112  5.837   27.414  1.00 74.94  ? 339 GLU D N   1 
ATOM   15161 C CA  . GLU D 1 279 ? -16.044  6.698   27.988  1.00 78.78  ? 339 GLU D CA  1 
ATOM   15162 C C   . GLU D 1 279 ? -16.244  6.816   29.505  1.00 80.39  ? 339 GLU D C   1 
ATOM   15163 O O   . GLU D 1 279 ? -15.383  6.292   30.249  1.00 75.10  ? 339 GLU D O   1 
ATOM   15164 C CB  . GLU D 1 279 ? -16.090  8.081   27.349  1.00 87.29  ? 339 GLU D CB  1 
ATOM   15165 C CG  . GLU D 1 279 ? -14.931  8.977   27.694  1.00 93.34  ? 339 GLU D CG  1 
ATOM   15166 C CD  . GLU D 1 279 ? -15.245  10.392  27.265  1.00 98.06  ? 339 GLU D CD  1 
ATOM   15167 O OE1 . GLU D 1 279 ? -14.904  10.743  26.108  1.00 91.47  ? 339 GLU D OE1 1 
ATOM   15168 O OE2 . GLU D 1 279 ? -15.903  11.095  28.067  1.00 104.66 ? 339 GLU D OE2 1 
ATOM   15169 N N   . LYS D 1 280 ? -17.342  7.444   29.959  1.00 71.68  ? 340 LYS D N   1 
ATOM   15170 C CA  . LYS D 1 280 ? -17.465  7.777   31.408  1.00 71.45  ? 340 LYS D CA  1 
ATOM   15171 C C   . LYS D 1 280 ? -17.751  6.523   32.264  1.00 57.32  ? 340 LYS D C   1 
ATOM   15172 O O   . LYS D 1 280 ? -17.247  6.543   33.386  1.00 60.06  ? 340 LYS D O   1 
ATOM   15173 C CB  . LYS D 1 280 ? -18.270  9.059   31.657  1.00 73.38  ? 340 LYS D CB  1 
ATOM   15174 C CG  . LYS D 1 280 ? -19.776  8.965   31.682  1.00 85.09  ? 340 LYS D CG  1 
ATOM   15175 C CD  . LYS D 1 280 ? -20.389  10.101  32.495  1.00 95.12  ? 340 LYS D CD  1 
ATOM   15176 C CE  . LYS D 1 280 ? -20.385  9.810   33.986  1.00 101.19 ? 340 LYS D CE  1 
ATOM   15177 N NZ  . LYS D 1 280 ? -20.720  11.001  34.806  1.00 102.69 ? 340 LYS D NZ  1 
ATOM   15178 N N   . TYR D 1 281 ? -18.317  5.419   31.774  1.00 50.18  ? 341 TYR D N   1 
ATOM   15179 C CA  . TYR D 1 281 ? -18.674  4.258   32.637  1.00 55.72  ? 341 TYR D CA  1 
ATOM   15180 C C   . TYR D 1 281 ? -17.746  3.053   32.404  1.00 56.83  ? 341 TYR D C   1 
ATOM   15181 O O   . TYR D 1 281 ? -18.069  1.968   32.935  1.00 58.03  ? 341 TYR D O   1 
ATOM   15182 C CB  . TYR D 1 281 ? -20.163  3.904   32.500  1.00 55.16  ? 341 TYR D CB  1 
ATOM   15183 C CG  . TYR D 1 281 ? -21.086  5.036   32.875  1.00 53.14  ? 341 TYR D CG  1 
ATOM   15184 C CD1 . TYR D 1 281 ? -21.313  5.395   34.191  1.00 53.21  ? 341 TYR D CD1 1 
ATOM   15185 C CD2 . TYR D 1 281 ? -21.694  5.794   31.893  1.00 54.98  ? 341 TYR D CD2 1 
ATOM   15186 C CE1 . TYR D 1 281 ? -22.134  6.464   34.513  1.00 49.70  ? 341 TYR D CE1 1 
ATOM   15187 C CE2 . TYR D 1 281 ? -22.515  6.864   32.189  1.00 49.76  ? 341 TYR D CE2 1 
ATOM   15188 C CZ  . TYR D 1 281 ? -22.731  7.197   33.507  1.00 48.88  ? 341 TYR D CZ  1 
ATOM   15189 O OH  . TYR D 1 281 ? -23.499  8.276   33.793  1.00 50.52  ? 341 TYR D OH  1 
ATOM   15190 N N   . SER D 1 282 ? -16.612  3.230   31.724  1.00 59.20  ? 342 SER D N   1 
ATOM   15191 C CA  . SER D 1 282 ? -15.569  2.177   31.565  1.00 61.64  ? 342 SER D CA  1 
ATOM   15192 C C   . SER D 1 282 ? -14.921  1.867   32.911  1.00 66.13  ? 342 SER D C   1 
ATOM   15193 O O   . SER D 1 282 ? -14.648  0.684   33.148  1.00 71.06  ? 342 SER D O   1 
ATOM   15194 C CB  . SER D 1 282 ? -14.528  2.557   30.562  1.00 61.47  ? 342 SER D CB  1 
ATOM   15195 O OG  . SER D 1 282 ? -15.082  2.582   29.260  1.00 62.93  ? 342 SER D OG  1 
ATOM   15196 N N   . LYS D 1 283 ? -14.725  2.891   33.747  1.00 77.58  ? 343 LYS D N   1 
ATOM   15197 C CA  . LYS D 1 283 ? -14.060  2.751   35.067  1.00 86.44  ? 343 LYS D CA  1 
ATOM   15198 C C   . LYS D 1 283 ? -15.027  2.096   36.067  1.00 78.24  ? 343 LYS D C   1 
ATOM   15199 O O   . LYS D 1 283 ? -14.716  0.996   36.595  1.00 68.35  ? 343 LYS D O   1 
ATOM   15200 C CB  . LYS D 1 283 ? -13.586  4.101   35.618  1.00 103.32 ? 343 LYS D CB  1 
ATOM   15201 C CG  . LYS D 1 283 ? -12.950  3.982   37.009  1.00 118.54 ? 343 LYS D CG  1 
ATOM   15202 C CD  . LYS D 1 283 ? -11.827  4.953   37.323  1.00 115.46 ? 343 LYS D CD  1 
ATOM   15203 C CE  . LYS D 1 283 ? -12.287  6.113   38.172  1.00 106.12 ? 343 LYS D CE  1 
ATOM   15204 N NZ  . LYS D 1 283 ? -11.122  6.815   38.741  1.00 104.06 ? 343 LYS D NZ  1 
ATOM   15205 N N   . SER D 1 284 ? -16.187  2.730   36.273  1.00 70.31  ? 344 SER D N   1 
ATOM   15206 C CA  . SER D 1 284 ? -17.165  2.377   37.335  1.00 69.51  ? 344 SER D CA  1 
ATOM   15207 C C   . SER D 1 284 ? -17.877  1.045   37.033  1.00 65.14  ? 344 SER D C   1 
ATOM   15208 O O   . SER D 1 284 ? -18.209  0.340   38.014  1.00 59.97  ? 344 SER D O   1 
ATOM   15209 C CB  . SER D 1 284 ? -18.119  3.521   37.557  1.00 72.29  ? 344 SER D CB  1 
ATOM   15210 O OG  . SER D 1 284 ? -18.382  4.213   36.341  1.00 66.06  ? 344 SER D OG  1 
ATOM   15211 N N   . HIS D 1 285 ? -18.100  0.692   35.755  1.00 64.77  ? 345 HIS D N   1 
ATOM   15212 C CA  . HIS D 1 285 ? -19.021  -0.409  35.338  1.00 65.57  ? 345 HIS D CA  1 
ATOM   15213 C C   . HIS D 1 285 ? -18.375  -1.377  34.338  1.00 54.51  ? 345 HIS D C   1 
ATOM   15214 O O   . HIS D 1 285 ? -17.320  -1.066  33.776  1.00 60.98  ? 345 HIS D O   1 
ATOM   15215 C CB  . HIS D 1 285 ? -20.330  0.175   34.757  1.00 69.94  ? 345 HIS D CB  1 
ATOM   15216 C CG  . HIS D 1 285 ? -21.119  1.036   35.699  1.00 67.04  ? 345 HIS D CG  1 
ATOM   15217 N ND1 . HIS D 1 285 ? -20.744  2.339   35.994  1.00 63.23  ? 345 HIS D ND1 1 
ATOM   15218 C CD2 . HIS D 1 285 ? -22.206  0.772   36.463  1.00 73.73  ? 345 HIS D CD2 1 
ATOM   15219 C CE1 . HIS D 1 285 ? -21.602  2.863   36.855  1.00 68.84  ? 345 HIS D CE1 1 
ATOM   15220 N NE2 . HIS D 1 285 ? -22.495  1.915   37.179  1.00 78.50  ? 345 HIS D NE2 1 
ATOM   15221 N N   . LEU D 1 286 ? -19.013  -2.523  34.131  1.00 47.86  ? 346 LEU D N   1 
ATOM   15222 C CA  . LEU D 1 286 ? -18.653  -3.472  33.045  1.00 47.40  ? 346 LEU D CA  1 
ATOM   15223 C C   . LEU D 1 286 ? -19.591  -3.184  31.861  1.00 50.47  ? 346 LEU D C   1 
ATOM   15224 O O   . LEU D 1 286 ? -20.625  -3.839  31.740  1.00 48.03  ? 346 LEU D O   1 
ATOM   15225 C CB  . LEU D 1 286 ? -18.743  -4.899  33.599  1.00 44.67  ? 346 LEU D CB  1 
ATOM   15226 C CG  . LEU D 1 286 ? -18.636  -6.047  32.602  1.00 47.01  ? 346 LEU D CG  1 
ATOM   15227 C CD1 . LEU D 1 286 ? -17.235  -6.153  32.063  1.00 59.24  ? 346 LEU D CD1 1 
ATOM   15228 C CD2 . LEU D 1 286 ? -19.019  -7.376  33.223  1.00 46.74  ? 346 LEU D CD2 1 
ATOM   15229 N N   . VAL D 1 287 ? -19.251  -2.176  31.052  1.00 59.70  ? 347 VAL D N   1 
ATOM   15230 C CA  . VAL D 1 287 ? -20.079  -1.666  29.917  1.00 53.29  ? 347 VAL D CA  1 
ATOM   15231 C C   . VAL D 1 287 ? -19.500  -2.196  28.596  1.00 56.91  ? 347 VAL D C   1 
ATOM   15232 O O   . VAL D 1 287 ? -18.267  -2.323  28.478  1.00 51.11  ? 347 VAL D O   1 
ATOM   15233 C CB  . VAL D 1 287 ? -20.186  -0.125  29.909  1.00 52.59  ? 347 VAL D CB  1 
ATOM   15234 C CG1 . VAL D 1 287 ? -20.753  0.380   31.220  1.00 58.45  ? 347 VAL D CG1 1 
ATOM   15235 C CG2 . VAL D 1 287 ? -18.877  0.591   29.581  1.00 45.17  ? 347 VAL D CG2 1 
ATOM   15236 N N   . PHE D 1 288 ? -20.378  -2.472  27.627  1.00 53.46  ? 348 PHE D N   1 
ATOM   15237 C CA  . PHE D 1 288 ? -20.055  -3.073  26.307  1.00 46.82  ? 348 PHE D CA  1 
ATOM   15238 C C   . PHE D 1 288 ? -21.057  -2.520  25.315  1.00 41.60  ? 348 PHE D C   1 
ATOM   15239 O O   . PHE D 1 288 ? -22.152  -2.396  25.753  1.00 49.00  ? 348 PHE D O   1 
ATOM   15240 C CB  . PHE D 1 288 ? -20.145  -4.600  26.397  1.00 43.92  ? 348 PHE D CB  1 
ATOM   15241 C CG  . PHE D 1 288 ? -20.090  -5.299  25.068  1.00 42.12  ? 348 PHE D CG  1 
ATOM   15242 C CD1 . PHE D 1 288 ? -18.894  -5.447  24.393  1.00 42.27  ? 348 PHE D CD1 1 
ATOM   15243 C CD2 . PHE D 1 288 ? -21.240  -5.802  24.496  1.00 51.05  ? 348 PHE D CD2 1 
ATOM   15244 C CE1 . PHE D 1 288 ? -18.854  -6.101  23.179  1.00 48.95  ? 348 PHE D CE1 1 
ATOM   15245 C CE2 . PHE D 1 288 ? -21.205  -6.460  23.278  1.00 55.04  ? 348 PHE D CE2 1 
ATOM   15246 C CZ  . PHE D 1 288 ? -20.011  -6.609  22.625  1.00 54.71  ? 348 PHE D CZ  1 
ATOM   15247 N N   . ASN D 1 289 ? -20.698  -2.185  24.082  1.00 48.27  ? 349 ASN D N   1 
ATOM   15248 C CA  . ASN D 1 289 ? -21.624  -1.539  23.101  1.00 55.77  ? 349 ASN D CA  1 
ATOM   15249 C C   . ASN D 1 289 ? -21.684  -2.424  21.851  1.00 55.14  ? 349 ASN D C   1 
ATOM   15250 O O   . ASN D 1 289 ? -20.685  -2.547  21.178  1.00 58.45  ? 349 ASN D O   1 
ATOM   15251 C CB  . ASN D 1 289 ? -21.229  -0.079  22.786  1.00 59.23  ? 349 ASN D CB  1 
ATOM   15252 C CG  . ASN D 1 289 ? -22.215  0.649   21.892  1.00 60.35  ? 349 ASN D CG  1 
ATOM   15253 O OD1 . ASN D 1 289 ? -22.481  0.202   20.782  1.00 67.09  ? 349 ASN D OD1 1 
ATOM   15254 N ND2 . ASN D 1 289 ? -22.754  1.769   22.347  1.00 52.71  ? 349 ASN D ND2 1 
ATOM   15255 N N   . ASP D 1 290 ? -22.829  -3.024  21.551  1.00 63.95  ? 350 ASP D N   1 
ATOM   15256 C CA  . ASP D 1 290 ? -22.935  -4.061  20.488  1.00 66.67  ? 350 ASP D CA  1 
ATOM   15257 C C   . ASP D 1 290 ? -22.623  -3.408  19.129  1.00 61.07  ? 350 ASP D C   1 
ATOM   15258 O O   . ASP D 1 290 ? -21.970  -4.092  18.291  1.00 55.17  ? 350 ASP D O   1 
ATOM   15259 C CB  . ASP D 1 290 ? -24.302  -4.758  20.526  1.00 67.63  ? 350 ASP D CB  1 
ATOM   15260 C CG  . ASP D 1 290 ? -24.267  -6.230  20.168  1.00 63.98  ? 350 ASP D CG  1 
ATOM   15261 O OD1 . ASP D 1 290 ? -23.167  -6.792  20.114  1.00 61.20  ? 350 ASP D OD1 1 
ATOM   15262 O OD2 . ASP D 1 290 ? -25.346  -6.798  19.966  1.00 67.21  ? 350 ASP D OD2 1 
ATOM   15263 N N   . ASP D 1 291 ? -23.015  -2.136  18.944  1.00 55.89  ? 351 ASP D N   1 
ATOM   15264 C CA  . ASP D 1 291 ? -22.856  -1.394  17.665  1.00 67.20  ? 351 ASP D CA  1 
ATOM   15265 C C   . ASP D 1 291 ? -21.372  -1.079  17.410  1.00 68.84  ? 351 ASP D C   1 
ATOM   15266 O O   . ASP D 1 291 ? -20.893  -1.311  16.275  1.00 70.83  ? 351 ASP D O   1 
ATOM   15267 C CB  . ASP D 1 291 ? -23.675  -0.099  17.645  1.00 77.85  ? 351 ASP D CB  1 
ATOM   15268 C CG  . ASP D 1 291 ? -25.050  -0.210  18.284  1.00 88.88  ? 351 ASP D CG  1 
ATOM   15269 O OD1 . ASP D 1 291 ? -25.713  -1.274  18.077  1.00 71.86  ? 351 ASP D OD1 1 
ATOM   15270 O OD2 . ASP D 1 291 ? -25.440  0.785   19.008  1.00 80.80  ? 351 ASP D OD2 1 
ATOM   15271 N N   . ILE D 1 292 ? -20.662  -0.574  18.419  1.00 66.46  ? 352 ILE D N   1 
ATOM   15272 C CA  . ILE D 1 292 ? -19.230  -0.152  18.288  1.00 60.90  ? 352 ILE D CA  1 
ATOM   15273 C C   . ILE D 1 292 ? -18.348  -1.398  18.403  1.00 54.61  ? 352 ILE D C   1 
ATOM   15274 O O   . ILE D 1 292 ? -17.718  -1.775  17.404  1.00 74.43  ? 352 ILE D O   1 
ATOM   15275 C CB  . ILE D 1 292 ? -18.854  0.927   19.328  1.00 62.97  ? 352 ILE D CB  1 
ATOM   15276 C CG1 . ILE D 1 292 ? -19.760  2.156   19.225  1.00 69.71  ? 352 ILE D CG1 1 
ATOM   15277 C CG2 . ILE D 1 292 ? -17.399  1.324   19.208  1.00 61.25  ? 352 ILE D CG2 1 
ATOM   15278 C CD1 . ILE D 1 292 ? -19.729  3.075   20.424  1.00 69.47  ? 352 ILE D CD1 1 
ATOM   15279 N N   . GLN D 1 293 ? -18.354  -2.036  19.565  1.00 50.51  ? 353 GLN D N   1 
ATOM   15280 C CA  . GLN D 1 293 ? -17.433  -3.141  19.941  1.00 55.45  ? 353 GLN D CA  1 
ATOM   15281 C C   . GLN D 1 293 ? -17.888  -4.488  19.343  1.00 54.00  ? 353 GLN D C   1 
ATOM   15282 O O   . GLN D 1 293 ? -17.034  -5.225  18.845  1.00 59.30  ? 353 GLN D O   1 
ATOM   15283 C CB  . GLN D 1 293 ? -17.286  -3.196  21.467  1.00 56.80  ? 353 GLN D CB  1 
ATOM   15284 C CG  . GLN D 1 293 ? -16.677  -1.932  22.085  1.00 57.44  ? 353 GLN D CG  1 
ATOM   15285 C CD  . GLN D 1 293 ? -16.799  -1.886  23.590  1.00 59.61  ? 353 GLN D CD  1 
ATOM   15286 O OE1 . GLN D 1 293 ? -17.854  -2.120  24.167  1.00 55.02  ? 353 GLN D OE1 1 
ATOM   15287 N NE2 . GLN D 1 293 ? -15.696  -1.584  24.255  1.00 67.60  ? 353 GLN D NE2 1 
ATOM   15288 N N   . GLY D 1 294 ? -19.168  -4.825  19.387  1.00 56.91  ? 354 GLY D N   1 
ATOM   15289 C CA  . GLY D 1 294 ? -19.637  -6.182  19.023  1.00 61.50  ? 354 GLY D CA  1 
ATOM   15290 C C   . GLY D 1 294 ? -19.522  -6.432  17.532  1.00 59.48  ? 354 GLY D C   1 
ATOM   15291 O O   . GLY D 1 294 ? -19.074  -7.535  17.143  1.00 41.61  ? 354 GLY D O   1 
ATOM   15292 N N   . THR D 1 295 ? -19.911  -5.423  16.744  1.00 58.27  ? 355 THR D N   1 
ATOM   15293 C CA  . THR D 1 295 ? -19.873  -5.432  15.260  1.00 59.32  ? 355 THR D CA  1 
ATOM   15294 C C   . THR D 1 295 ? -18.403  -5.431  14.821  1.00 58.93  ? 355 THR D C   1 
ATOM   15295 O O   . THR D 1 295 ? -18.003  -6.337  14.045  1.00 64.36  ? 355 THR D O   1 
ATOM   15296 C CB  . THR D 1 295 ? -20.684  -4.257  14.696  1.00 55.48  ? 355 THR D CB  1 
ATOM   15297 O OG1 . THR D 1 295 ? -21.975  -4.246  15.297  1.00 56.43  ? 355 THR D OG1 1 
ATOM   15298 C CG2 . THR D 1 295 ? -20.878  -4.344  13.205  1.00 46.36  ? 355 THR D CG2 1 
ATOM   15299 N N   . ALA D 1 296 ? -17.618  -4.469  15.323  1.00 57.66  ? 356 ALA D N   1 
ATOM   15300 C CA  . ALA D 1 296 ? -16.147  -4.412  15.129  1.00 54.73  ? 356 ALA D CA  1 
ATOM   15301 C C   . ALA D 1 296 ? -15.579  -5.824  15.283  1.00 48.24  ? 356 ALA D C   1 
ATOM   15302 O O   . ALA D 1 296 ? -14.833  -6.245  14.421  1.00 52.08  ? 356 ALA D O   1 
ATOM   15303 C CB  . ALA D 1 296 ? -15.527  -3.458  16.104  1.00 51.49  ? 356 ALA D CB  1 
ATOM   15304 N N   . SER D 1 297 ? -15.972  -6.528  16.335  1.00 47.64  ? 357 SER D N   1 
ATOM   15305 C CA  . SER D 1 297 ? -15.440  -7.863  16.700  1.00 51.13  ? 357 SER D CA  1 
ATOM   15306 C C   . SER D 1 297 ? -15.731  -8.870  15.583  1.00 53.73  ? 357 SER D C   1 
ATOM   15307 O O   . SER D 1 297 ? -14.790  -9.544  15.146  1.00 60.10  ? 357 SER D O   1 
ATOM   15308 C CB  . SER D 1 297 ? -15.999  -8.333  18.002  1.00 48.09  ? 357 SER D CB  1 
ATOM   15309 O OG  . SER D 1 297 ? -15.245  -9.432  18.471  1.00 51.05  ? 357 SER D OG  1 
ATOM   15310 N N   . VAL D 1 298 ? -16.975  -8.966  15.127  1.00 48.83  ? 358 VAL D N   1 
ATOM   15311 C CA  . VAL D 1 298 ? -17.408  -10.029 14.169  1.00 51.54  ? 358 VAL D CA  1 
ATOM   15312 C C   . VAL D 1 298 ? -16.870  -9.724  12.766  1.00 53.55  ? 358 VAL D C   1 
ATOM   15313 O O   . VAL D 1 298 ? -16.631  -10.690 11.976  1.00 49.89  ? 358 VAL D O   1 
ATOM   15314 C CB  . VAL D 1 298 ? -18.941  -10.174 14.132  1.00 51.53  ? 358 VAL D CB  1 
ATOM   15315 C CG1 . VAL D 1 298 ? -19.625  -8.918  13.596  1.00 54.93  ? 358 VAL D CG1 1 
ATOM   15316 C CG2 . VAL D 1 298 ? -19.360  -11.415 13.357  1.00 47.15  ? 358 VAL D CG2 1 
ATOM   15317 N N   . VAL D 1 299 ? -16.742  -8.436  12.451  1.00 49.73  ? 359 VAL D N   1 
ATOM   15318 C CA  . VAL D 1 299 ? -16.188  -7.966  11.153  1.00 50.20  ? 359 VAL D CA  1 
ATOM   15319 C C   . VAL D 1 299 ? -14.723  -8.394  11.084  1.00 51.02  ? 359 VAL D C   1 
ATOM   15320 O O   . VAL D 1 299 ? -14.338  -9.008  10.078  1.00 52.01  ? 359 VAL D O   1 
ATOM   15321 C CB  . VAL D 1 299 ? -16.347  -6.442  10.981  1.00 48.98  ? 359 VAL D CB  1 
ATOM   15322 C CG1 . VAL D 1 299 ? -15.491  -5.914  9.838   1.00 48.83  ? 359 VAL D CG1 1 
ATOM   15323 C CG2 . VAL D 1 299 ? -17.810  -6.077  10.782  1.00 46.59  ? 359 VAL D CG2 1 
ATOM   15324 N N   . LEU D 1 300 ? -13.937  -8.071  12.110  1.00 52.67  ? 360 LEU D N   1 
ATOM   15325 C CA  . LEU D 1 300 ? -12.502  -8.438  12.175  1.00 55.15  ? 360 LEU D CA  1 
ATOM   15326 C C   . LEU D 1 300 ? -12.398  -9.951  11.981  1.00 52.30  ? 360 LEU D C   1 
ATOM   15327 O O   . LEU D 1 300 ? -11.535  -10.363 11.230  1.00 61.16  ? 360 LEU D O   1 
ATOM   15328 C CB  . LEU D 1 300 ? -11.912  -7.971  13.513  1.00 64.21  ? 360 LEU D CB  1 
ATOM   15329 C CG  . LEU D 1 300 ? -10.407  -8.156  13.734  1.00 65.31  ? 360 LEU D CG  1 
ATOM   15330 C CD1 . LEU D 1 300 ? -9.588   -7.211  12.873  1.00 71.25  ? 360 LEU D CD1 1 
ATOM   15331 C CD2 . LEU D 1 300 ? -10.050  -7.945  15.192  1.00 60.18  ? 360 LEU D CD2 1 
ATOM   15332 N N   . ALA D 1 301 ? -13.280  -10.740 12.598  1.00 54.37  ? 361 ALA D N   1 
ATOM   15333 C CA  . ALA D 1 301 ? -13.296  -12.221 12.477  1.00 55.06  ? 361 ALA D CA  1 
ATOM   15334 C C   . ALA D 1 301 ? -13.602  -12.605 11.028  1.00 49.47  ? 361 ALA D C   1 
ATOM   15335 O O   . ALA D 1 301 ? -13.023  -13.565 10.530  1.00 54.55  ? 361 ALA D O   1 
ATOM   15336 C CB  . ALA D 1 301 ? -14.313  -12.825 13.423  1.00 56.38  ? 361 ALA D CB  1 
ATOM   15337 N N   . GLY D 1 302 ? -14.535  -11.901 10.404  1.00 41.11  ? 362 GLY D N   1 
ATOM   15338 C CA  . GLY D 1 302 ? -14.869  -12.108 8.992   1.00 44.95  ? 362 GLY D CA  1 
ATOM   15339 C C   . GLY D 1 302 ? -13.672  -11.853 8.095   1.00 45.80  ? 362 GLY D C   1 
ATOM   15340 O O   . GLY D 1 302 ? -13.382  -12.722 7.255   1.00 56.24  ? 362 GLY D O   1 
ATOM   15341 N N   . LEU D 1 303 ? -13.008  -10.711 8.269   1.00 49.71  ? 363 LEU D N   1 
ATOM   15342 C CA  . LEU D 1 303 ? -11.748  -10.357 7.550   1.00 51.03  ? 363 LEU D CA  1 
ATOM   15343 C C   . LEU D 1 303 ? -10.729  -11.489 7.712   1.00 50.23  ? 363 LEU D C   1 
ATOM   15344 O O   . LEU D 1 303 ? -10.302  -11.988 6.694   1.00 51.52  ? 363 LEU D O   1 
ATOM   15345 C CB  . LEU D 1 303 ? -11.197  -9.024  8.053   1.00 48.76  ? 363 LEU D CB  1 
ATOM   15346 C CG  . LEU D 1 303 ? -12.111  -7.837  7.750   1.00 60.03  ? 363 LEU D CG  1 
ATOM   15347 C CD1 . LEU D 1 303 ? -11.581  -6.539  8.347   1.00 65.67  ? 363 LEU D CD1 1 
ATOM   15348 C CD2 . LEU D 1 303 ? -12.350  -7.668  6.262   1.00 58.95  ? 363 LEU D CD2 1 
ATOM   15349 N N   . LEU D 1 304 ? -10.405  -11.924 8.933   1.00 51.69  ? 364 LEU D N   1 
ATOM   15350 C CA  . LEU D 1 304 ? -9.405   -13.007 9.178   1.00 57.63  ? 364 LEU D CA  1 
ATOM   15351 C C   . LEU D 1 304 ? -9.841   -14.301 8.473   1.00 61.67  ? 364 LEU D C   1 
ATOM   15352 O O   . LEU D 1 304 ? -8.953   -15.031 7.971   1.00 62.31  ? 364 LEU D O   1 
ATOM   15353 C CB  . LEU D 1 304 ? -9.231   -13.254 10.677  1.00 57.99  ? 364 LEU D CB  1 
ATOM   15354 C CG  . LEU D 1 304 ? -8.245   -12.319 11.385  1.00 59.79  ? 364 LEU D CG  1 
ATOM   15355 C CD1 . LEU D 1 304 ? -6.843   -12.540 10.885  1.00 68.85  ? 364 LEU D CD1 1 
ATOM   15356 C CD2 . LEU D 1 304 ? -8.594   -10.860 11.215  1.00 66.48  ? 364 LEU D CD2 1 
ATOM   15357 N N   . ALA D 1 305 ? -11.147  -14.568 8.428   1.00 57.23  ? 365 ALA D N   1 
ATOM   15358 C CA  . ALA D 1 305 ? -11.736  -15.779 7.813   1.00 58.21  ? 365 ALA D CA  1 
ATOM   15359 C C   . ALA D 1 305 ? -11.627  -15.664 6.292   1.00 57.16  ? 365 ALA D C   1 
ATOM   15360 O O   . ALA D 1 305 ? -11.403  -16.723 5.635   1.00 53.45  ? 365 ALA D O   1 
ATOM   15361 C CB  . ALA D 1 305 ? -13.170  -15.976 8.262   1.00 57.97  ? 365 ALA D CB  1 
ATOM   15362 N N   . ALA D 1 306 ? -11.792  -14.433 5.777   1.00 57.81  ? 366 ALA D N   1 
ATOM   15363 C CA  . ALA D 1 306 ? -11.737  -14.088 4.330   1.00 57.13  ? 366 ALA D CA  1 
ATOM   15364 C C   . ALA D 1 306 ? -10.314  -14.345 3.833   1.00 62.24  ? 366 ALA D C   1 
ATOM   15365 O O   . ALA D 1 306 ? -10.154  -14.983 2.751   1.00 68.93  ? 366 ALA D O   1 
ATOM   15366 C CB  . ALA D 1 306 ? -12.140  -12.652 4.079   1.00 53.13  ? 366 ALA D CB  1 
ATOM   15367 N N   . LEU D 1 307 ? -9.328   -13.919 4.634   1.00 60.69  ? 367 LEU D N   1 
ATOM   15368 C CA  . LEU D 1 307 ? -7.897   -13.919 4.253   1.00 51.45  ? 367 LEU D CA  1 
ATOM   15369 C C   . LEU D 1 307 ? -7.371   -15.353 4.314   1.00 54.81  ? 367 LEU D C   1 
ATOM   15370 O O   . LEU D 1 307 ? -6.304   -15.576 3.773   1.00 58.18  ? 367 LEU D O   1 
ATOM   15371 C CB  . LEU D 1 307 ? -7.126   -12.968 5.169   1.00 50.30  ? 367 LEU D CB  1 
ATOM   15372 C CG  . LEU D 1 307 ? -7.516   -11.483 5.028   1.00 53.34  ? 367 LEU D CG  1 
ATOM   15373 C CD1 . LEU D 1 307 ? -6.644   -10.577 5.881   1.00 54.92  ? 367 LEU D CD1 1 
ATOM   15374 C CD2 . LEU D 1 307 ? -7.474   -10.988 3.586   1.00 52.17  ? 367 LEU D CD2 1 
ATOM   15375 N N   . LYS D 1 308 ? -8.126   -16.293 4.868   1.00 57.21  ? 368 LYS D N   1 
ATOM   15376 C CA  . LYS D 1 308 ? -7.824   -17.737 4.779   1.00 51.66  ? 368 LYS D CA  1 
ATOM   15377 C C   . LYS D 1 308 ? -8.314   -18.271 3.441   1.00 57.35  ? 368 LYS D C   1 
ATOM   15378 O O   . LYS D 1 308 ? -7.656   -19.195 2.942   1.00 79.41  ? 368 LYS D O   1 
ATOM   15379 C CB  . LYS D 1 308 ? -8.491   -18.531 5.907   1.00 60.47  ? 368 LYS D CB  1 
ATOM   15380 C CG  . LYS D 1 308 ? -8.706   -17.798 7.224   1.00 73.39  ? 368 LYS D CG  1 
ATOM   15381 C CD  . LYS D 1 308 ? -7.996   -18.405 8.402   1.00 73.42  ? 368 LYS D CD  1 
ATOM   15382 C CE  . LYS D 1 308 ? -8.792   -18.267 9.678   1.00 77.94  ? 368 LYS D CE  1 
ATOM   15383 N NZ  . LYS D 1 308 ? -8.249   -19.133 10.755  1.00 84.83  ? 368 LYS D NZ  1 
ATOM   15384 N N   . MET D 1 309 ? -9.412   -17.748 2.880   1.00 58.97  ? 369 MET D N   1 
ATOM   15385 C CA  . MET D 1 309 ? -9.910   -18.265 1.578   1.00 64.45  ? 369 MET D CA  1 
ATOM   15386 C C   . MET D 1 309 ? -9.018   -17.719 0.453   1.00 62.39  ? 369 MET D C   1 
ATOM   15387 O O   . MET D 1 309 ? -8.620   -18.542 -0.432  1.00 59.84  ? 369 MET D O   1 
ATOM   15388 C CB  . MET D 1 309 ? -11.378  -17.962 1.236   1.00 75.79  ? 369 MET D CB  1 
ATOM   15389 C CG  . MET D 1 309 ? -12.243  -17.087 2.174   1.00 88.74  ? 369 MET D CG  1 
ATOM   15390 S SD  . MET D 1 309 ? -14.035  -17.516 2.306   1.00 94.48  ? 369 MET D SD  1 
ATOM   15391 C CE  . MET D 1 309 ? -14.218  -18.879 1.149   1.00 85.85  ? 369 MET D CE  1 
ATOM   15392 N N   . VAL D 1 310 ? -8.718   -16.410 0.497   1.00 54.71  ? 370 VAL D N   1 
ATOM   15393 C CA  . VAL D 1 310 ? -8.026   -15.670 -0.601  1.00 54.33  ? 370 VAL D CA  1 
ATOM   15394 C C   . VAL D 1 310 ? -6.520   -15.528 -0.329  1.00 54.54  ? 370 VAL D C   1 
ATOM   15395 O O   . VAL D 1 310 ? -5.787   -15.372 -1.309  1.00 63.64  ? 370 VAL D O   1 
ATOM   15396 C CB  . VAL D 1 310 ? -8.679   -14.295 -0.868  1.00 64.77  ? 370 VAL D CB  1 
ATOM   15397 C CG1 . VAL D 1 310 ? -10.152  -14.456 -1.191  1.00 78.24  ? 370 VAL D CG1 1 
ATOM   15398 C CG2 . VAL D 1 310 ? -8.485   -13.276 0.244   1.00 67.05  ? 370 VAL D CG2 1 
ATOM   15399 N N   . GLY D 1 311 ? -6.075   -15.547 0.932   1.00 53.89  ? 371 GLY D N   1 
ATOM   15400 C CA  . GLY D 1 311 ? -4.679   -15.266 1.320   1.00 56.80  ? 371 GLY D CA  1 
ATOM   15401 C C   . GLY D 1 311 ? -4.454   -13.793 1.666   1.00 63.48  ? 371 GLY D C   1 
ATOM   15402 O O   . GLY D 1 311 ? -5.192   -12.903 1.122   1.00 58.44  ? 371 GLY D O   1 
ATOM   15403 N N   . GLY D 1 312 ? -3.455   -13.533 2.518   1.00 62.39  ? 372 GLY D N   1 
ATOM   15404 C CA  . GLY D 1 312 ? -2.954   -12.175 2.811   1.00 57.70  ? 372 GLY D CA  1 
ATOM   15405 C C   . GLY D 1 312 ? -3.108   -11.815 4.268   1.00 56.19  ? 372 GLY D C   1 
ATOM   15406 O O   . GLY D 1 312 ? -3.556   -12.679 5.068   1.00 66.03  ? 372 GLY D O   1 
ATOM   15407 N N   . THR D 1 313 ? -2.751   -10.580 4.611   1.00 54.42  ? 373 THR D N   1 
ATOM   15408 C CA  . THR D 1 313 ? -2.751   -10.063 6.001   1.00 64.30  ? 373 THR D CA  1 
ATOM   15409 C C   . THR D 1 313 ? -3.666   -8.849  6.067   1.00 59.65  ? 373 THR D C   1 
ATOM   15410 O O   . THR D 1 313 ? -3.964   -8.327  4.995   1.00 60.38  ? 373 THR D O   1 
ATOM   15411 C CB  . THR D 1 313 ? -1.328   -9.677  6.426   1.00 73.91  ? 373 THR D CB  1 
ATOM   15412 O OG1 . THR D 1 313 ? -0.986   -8.431  5.803   1.00 67.11  ? 373 THR D OG1 1 
ATOM   15413 C CG2 . THR D 1 313 ? -0.314   -10.755 6.102   1.00 73.65  ? 373 THR D CG2 1 
ATOM   15414 N N   . LEU D 1 314 ? -4.052   -8.419  7.262   1.00 53.35  ? 374 LEU D N   1 
ATOM   15415 C CA  . LEU D 1 314 ? -4.867   -7.190  7.452   1.00 55.02  ? 374 LEU D CA  1 
ATOM   15416 C C   . LEU D 1 314 ? -4.011   -6.000  7.008   1.00 56.82  ? 374 LEU D C   1 
ATOM   15417 O O   . LEU D 1 314 ? -4.537   -5.087  6.344   1.00 69.04  ? 374 LEU D O   1 
ATOM   15418 C CB  . LEU D 1 314 ? -5.288   -7.007  8.917   1.00 60.55  ? 374 LEU D CB  1 
ATOM   15419 C CG  . LEU D 1 314 ? -6.226   -8.062  9.491   1.00 65.35  ? 374 LEU D CG  1 
ATOM   15420 C CD1 . LEU D 1 314 ? -7.543   -8.073  8.707   1.00 72.16  ? 374 LEU D CD1 1 
ATOM   15421 C CD2 . LEU D 1 314 ? -5.535   -9.431  9.481   1.00 70.35  ? 374 LEU D CD2 1 
ATOM   15422 N N   . ALA D 1 315 ? -2.723   -6.027  7.339   1.00 58.95  ? 375 ALA D N   1 
ATOM   15423 C CA  . ALA D 1 315 ? -1.797   -4.898  7.109   1.00 61.74  ? 375 ALA D CA  1 
ATOM   15424 C C   . ALA D 1 315 ? -1.912   -4.456  5.645   1.00 63.09  ? 375 ALA D C   1 
ATOM   15425 O O   . ALA D 1 315 ? -2.196   -3.257  5.414   1.00 69.26  ? 375 ALA D O   1 
ATOM   15426 C CB  . ALA D 1 315 ? -0.396   -5.301  7.476   1.00 67.28  ? 375 ALA D CB  1 
ATOM   15427 N N   . GLU D 1 316 ? -1.756   -5.397  4.697   1.00 59.53  ? 376 GLU D N   1 
ATOM   15428 C CA  . GLU D 1 316 ? -1.586   -5.072  3.249   1.00 59.46  ? 376 GLU D CA  1 
ATOM   15429 C C   . GLU D 1 316 ? -2.914   -4.656  2.599   1.00 54.83  ? 376 GLU D C   1 
ATOM   15430 O O   . GLU D 1 316 ? -2.827   -4.040  1.544   1.00 54.68  ? 376 GLU D O   1 
ATOM   15431 C CB  . GLU D 1 316 ? -0.867   -6.173  2.464   1.00 69.67  ? 376 GLU D CB  1 
ATOM   15432 C CG  . GLU D 1 316 ? -1.499   -7.553  2.566   1.00 78.82  ? 376 GLU D CG  1 
ATOM   15433 C CD  . GLU D 1 316 ? -0.515   -8.702  2.652   1.00 76.53  ? 376 GLU D CD  1 
ATOM   15434 O OE1 . GLU D 1 316 ? 0.683    -8.480  2.880   1.00 75.34  ? 376 GLU D OE1 1 
ATOM   15435 O OE2 . GLU D 1 316 ? -0.957   -9.832  2.497   1.00 92.47  ? 376 GLU D OE2 1 
ATOM   15436 N N   . GLN D 1 317 ? -4.092   -4.936  3.160   1.00 51.61  ? 377 GLN D N   1 
ATOM   15437 C CA  . GLN D 1 317 ? -5.391   -4.550  2.535   1.00 51.38  ? 377 GLN D CA  1 
ATOM   15438 C C   . GLN D 1 317 ? -5.601   -3.021  2.612   1.00 57.53  ? 377 GLN D C   1 
ATOM   15439 O O   . GLN D 1 317 ? -5.000   -2.322  3.515   1.00 50.87  ? 377 GLN D O   1 
ATOM   15440 C CB  . GLN D 1 317 ? -6.548   -5.248  3.231   1.00 55.54  ? 377 GLN D CB  1 
ATOM   15441 C CG  . GLN D 1 317 ? -6.361   -6.744  3.436   1.00 58.94  ? 377 GLN D CG  1 
ATOM   15442 C CD  . GLN D 1 317 ? -6.189   -7.498  2.152   1.00 49.51  ? 377 GLN D CD  1 
ATOM   15443 O OE1 . GLN D 1 317 ? -6.904   -7.256  1.185   1.00 45.65  ? 377 GLN D OE1 1 
ATOM   15444 N NE2 . GLN D 1 317 ? -5.253   -8.431  2.162   1.00 50.93  ? 377 GLN D NE2 1 
ATOM   15445 N N   . THR D 1 318 ? -6.436   -2.500  1.709   1.00 57.12  ? 378 THR D N   1 
ATOM   15446 C CA  . THR D 1 318 ? -6.956   -1.104  1.747   1.00 61.27  ? 378 THR D CA  1 
ATOM   15447 C C   . THR D 1 318 ? -8.475   -1.154  1.948   1.00 65.05  ? 378 THR D C   1 
ATOM   15448 O O   . THR D 1 318 ? -9.173   -1.849  1.143   1.00 72.88  ? 378 THR D O   1 
ATOM   15449 C CB  . THR D 1 318 ? -6.556   -0.304  0.496   1.00 58.77  ? 378 THR D CB  1 
ATOM   15450 O OG1 . THR D 1 318 ? -5.135   -0.391  0.402   1.00 59.99  ? 378 THR D OG1 1 
ATOM   15451 C CG2 . THR D 1 318 ? -6.959   1.159   0.533   1.00 56.48  ? 378 THR D CG2 1 
ATOM   15452 N N   . TYR D 1 319 ? -8.955   -0.428  2.970   1.00 59.95  ? 379 TYR D N   1 
ATOM   15453 C CA  . TYR D 1 319 ? -10.346  -0.456  3.486   1.00 55.71  ? 379 TYR D CA  1 
ATOM   15454 C C   . TYR D 1 319 ? -11.101  0.815   3.086   1.00 52.77  ? 379 TYR D C   1 
ATOM   15455 O O   . TYR D 1 319 ? -10.600  1.924   3.358   1.00 39.99  ? 379 TYR D O   1 
ATOM   15456 C CB  . TYR D 1 319 ? -10.313  -0.569  5.008   1.00 68.11  ? 379 TYR D CB  1 
ATOM   15457 C CG  . TYR D 1 319 ? -9.528   -1.752  5.508   1.00 69.91  ? 379 TYR D CG  1 
ATOM   15458 C CD1 . TYR D 1 319 ? -8.183   -1.629  5.820   1.00 64.09  ? 379 TYR D CD1 1 
ATOM   15459 C CD2 . TYR D 1 319 ? -10.118  -3.005  5.613   1.00 67.13  ? 379 TYR D CD2 1 
ATOM   15460 C CE1 . TYR D 1 319 ? -7.454   -2.718  6.260   1.00 62.57  ? 379 TYR D CE1 1 
ATOM   15461 C CE2 . TYR D 1 319 ? -9.395   -4.102  6.039   1.00 64.06  ? 379 TYR D CE2 1 
ATOM   15462 C CZ  . TYR D 1 319 ? -8.061   -3.957  6.363   1.00 60.02  ? 379 TYR D CZ  1 
ATOM   15463 O OH  . TYR D 1 319 ? -7.369   -5.051  6.785   1.00 62.12  ? 379 TYR D OH  1 
ATOM   15464 N N   . LEU D 1 320 ? -12.279  0.643   2.479   1.00 54.57  ? 380 LEU D N   1 
ATOM   15465 C CA  . LEU D 1 320 ? -13.257  1.731   2.254   1.00 47.40  ? 380 LEU D CA  1 
ATOM   15466 C C   . LEU D 1 320 ? -14.583  1.395   2.929   1.00 52.64  ? 380 LEU D C   1 
ATOM   15467 O O   . LEU D 1 320 ? -15.187  0.348   2.615   1.00 53.09  ? 380 LEU D O   1 
ATOM   15468 C CB  . LEU D 1 320 ? -13.476  1.934   0.762   1.00 48.82  ? 380 LEU D CB  1 
ATOM   15469 C CG  . LEU D 1 320 ? -14.257  3.199   0.405   1.00 51.20  ? 380 LEU D CG  1 
ATOM   15470 C CD1 . LEU D 1 320 ? -13.675  4.431   1.078   1.00 50.61  ? 380 LEU D CD1 1 
ATOM   15471 C CD2 . LEU D 1 320 ? -14.313  3.394   -1.095  1.00 50.99  ? 380 LEU D CD2 1 
ATOM   15472 N N   . PHE D 1 321 ? -15.021  2.300   3.814   1.00 64.56  ? 381 PHE D N   1 
ATOM   15473 C CA  . PHE D 1 321 ? -16.302  2.281   4.571   1.00 58.49  ? 381 PHE D CA  1 
ATOM   15474 C C   . PHE D 1 321 ? -17.296  3.294   3.988   1.00 55.61  ? 381 PHE D C   1 
ATOM   15475 O O   . PHE D 1 321 ? -16.951  4.464   3.701   1.00 48.89  ? 381 PHE D O   1 
ATOM   15476 C CB  . PHE D 1 321 ? -16.049  2.615   6.044   1.00 60.44  ? 381 PHE D CB  1 
ATOM   15477 C CG  . PHE D 1 321 ? -15.231  1.586   6.791   1.00 64.76  ? 381 PHE D CG  1 
ATOM   15478 C CD1 . PHE D 1 321 ? -13.847  1.642   6.793   1.00 61.40  ? 381 PHE D CD1 1 
ATOM   15479 C CD2 . PHE D 1 321 ? -15.841  0.509   7.423   1.00 63.98  ? 381 PHE D CD2 1 
ATOM   15480 C CE1 . PHE D 1 321 ? -13.100  0.656   7.430   1.00 66.02  ? 381 PHE D CE1 1 
ATOM   15481 C CE2 . PHE D 1 321 ? -15.092  -0.466  8.066   1.00 63.02  ? 381 PHE D CE2 1 
ATOM   15482 C CZ  . PHE D 1 321 ? -13.724  -0.403  8.065   1.00 63.37  ? 381 PHE D CZ  1 
ATOM   15483 N N   . LEU D 1 322 ? -18.526  2.848   3.769   1.00 59.03  ? 382 LEU D N   1 
ATOM   15484 C CA  . LEU D 1 322 ? -19.685  3.754   3.653   1.00 56.36  ? 382 LEU D CA  1 
ATOM   15485 C C   . LEU D 1 322 ? -20.325  3.790   5.038   1.00 56.59  ? 382 LEU D C   1 
ATOM   15486 O O   . LEU D 1 322 ? -20.665  2.704   5.556   1.00 55.54  ? 382 LEU D O   1 
ATOM   15487 C CB  . LEU D 1 322 ? -20.645  3.274   2.560   1.00 62.45  ? 382 LEU D CB  1 
ATOM   15488 C CG  . LEU D 1 322 ? -21.831  4.226   2.284   1.00 68.22  ? 382 LEU D CG  1 
ATOM   15489 C CD1 . LEU D 1 322 ? -21.416  5.655   1.936   1.00 64.99  ? 382 LEU D CD1 1 
ATOM   15490 C CD2 . LEU D 1 322 ? -22.748  3.685   1.195   1.00 66.49  ? 382 LEU D CD2 1 
ATOM   15491 N N   . GLY D 1 323 ? -20.429  4.992   5.623   1.00 62.96  ? 383 GLY D N   1 
ATOM   15492 C CA  . GLY D 1 323 ? -21.024  5.237   6.953   1.00 60.62  ? 383 GLY D CA  1 
ATOM   15493 C C   . GLY D 1 323 ? -19.959  5.322   8.042   1.00 60.50  ? 383 GLY D C   1 
ATOM   15494 O O   . GLY D 1 323 ? -19.430  4.269   8.415   1.00 57.41  ? 383 GLY D O   1 
ATOM   15495 N N   . ALA D 1 324 ? -19.672  6.533   8.530   1.00 62.49  ? 384 ALA D N   1 
ATOM   15496 C CA  . ALA D 1 324 ? -18.652  6.868   9.559   1.00 54.95  ? 384 ALA D CA  1 
ATOM   15497 C C   . ALA D 1 324 ? -19.328  7.143   10.893  1.00 57.14  ? 384 ALA D C   1 
ATOM   15498 O O   . ALA D 1 324 ? -19.157  8.252   11.425  1.00 55.01  ? 384 ALA D O   1 
ATOM   15499 C CB  . ALA D 1 324 ? -17.874  8.093   9.140   1.00 51.40  ? 384 ALA D CB  1 
ATOM   15500 N N   . GLY D 1 325 ? -20.120  6.192   11.385  1.00 61.50  ? 385 GLY D N   1 
ATOM   15501 C CA  . GLY D 1 325 ? -20.831  6.340   12.667  1.00 61.06  ? 385 GLY D CA  1 
ATOM   15502 C C   . GLY D 1 325 ? -20.128  5.549   13.736  1.00 58.75  ? 385 GLY D C   1 
ATOM   15503 O O   . GLY D 1 325 ? -18.902  5.428   13.638  1.00 55.52  ? 385 GLY D O   1 
ATOM   15504 N N   . GLU D 1 326 ? -20.889  5.033   14.704  1.00 66.11  ? 386 GLU D N   1 
ATOM   15505 C CA  . GLU D 1 326 ? -20.463  3.999   15.681  1.00 70.34  ? 386 GLU D CA  1 
ATOM   15506 C C   . GLU D 1 326 ? -19.779  2.840   14.959  1.00 60.09  ? 386 GLU D C   1 
ATOM   15507 O O   . GLU D 1 326 ? -18.564  2.716   15.107  1.00 72.17  ? 386 GLU D O   1 
ATOM   15508 C CB  . GLU D 1 326 ? -21.660  3.475   16.482  1.00 80.02  ? 386 GLU D CB  1 
ATOM   15509 C CG  . GLU D 1 326 ? -22.241  4.525   17.396  1.00 82.81  ? 386 GLU D CG  1 
ATOM   15510 C CD  . GLU D 1 326 ? -23.750  4.504   17.453  1.00 84.91  ? 386 GLU D CD  1 
ATOM   15511 O OE1 . GLU D 1 326 ? -24.379  5.198   16.603  1.00 92.63  ? 386 GLU D OE1 1 
ATOM   15512 O OE2 . GLU D 1 326 ? -24.291  3.848   18.380  1.00 86.28  ? 386 GLU D OE2 1 
ATOM   15513 N N   . ALA D 1 327 ? -20.515  2.037   14.206  1.00 56.63  ? 387 ALA D N   1 
ATOM   15514 C CA  . ALA D 1 327 ? -19.971  0.796   13.604  1.00 66.82  ? 387 ALA D CA  1 
ATOM   15515 C C   . ALA D 1 327 ? -18.823  1.154   12.649  1.00 62.08  ? 387 ALA D C   1 
ATOM   15516 O O   . ALA D 1 327 ? -17.804  0.460   12.652  1.00 60.40  ? 387 ALA D O   1 
ATOM   15517 C CB  . ALA D 1 327 ? -21.063  0.003   12.926  1.00 65.24  ? 387 ALA D CB  1 
ATOM   15518 N N   . GLY D 1 328 ? -18.985  2.220   11.875  1.00 63.79  ? 388 GLY D N   1 
ATOM   15519 C CA  . GLY D 1 328 ? -17.950  2.692   10.940  1.00 62.57  ? 388 GLY D CA  1 
ATOM   15520 C C   . GLY D 1 328 ? -16.609  2.819   11.640  1.00 66.78  ? 388 GLY D C   1 
ATOM   15521 O O   . GLY D 1 328 ? -15.744  1.907   11.434  1.00 59.35  ? 388 GLY D O   1 
ATOM   15522 N N   . THR D 1 329 ? -16.440  3.883   12.451  1.00 58.26  ? 389 THR D N   1 
ATOM   15523 C CA  . THR D 1 329 ? -15.162  4.210   13.131  1.00 45.84  ? 389 THR D CA  1 
ATOM   15524 C C   . THR D 1 329 ? -14.803  3.054   14.064  1.00 39.58  ? 389 THR D C   1 
ATOM   15525 O O   . THR D 1 329 ? -13.645  2.713   14.126  1.00 45.68  ? 389 THR D O   1 
ATOM   15526 C CB  . THR D 1 329 ? -15.234  5.570   13.845  1.00 47.74  ? 389 THR D CB  1 
ATOM   15527 O OG1 . THR D 1 329 ? -16.196  5.491   14.896  1.00 50.49  ? 389 THR D OG1 1 
ATOM   15528 C CG2 . THR D 1 329 ? -15.572  6.708   12.912  1.00 46.70  ? 389 THR D CG2 1 
ATOM   15529 N N   . GLY D 1 330 ? -15.774  2.481   14.758  1.00 41.60  ? 390 GLY D N   1 
ATOM   15530 C CA  . GLY D 1 330 ? -15.590  1.331   15.668  1.00 50.81  ? 390 GLY D CA  1 
ATOM   15531 C C   . GLY D 1 330 ? -14.949  0.126   14.994  1.00 52.61  ? 390 GLY D C   1 
ATOM   15532 O O   . GLY D 1 330 ? -13.976  -0.352  15.536  1.00 56.91  ? 390 GLY D O   1 
ATOM   15533 N N   . ILE D 1 331 ? -15.470  -0.343  13.860  1.00 55.71  ? 391 ILE D N   1 
ATOM   15534 C CA  . ILE D 1 331 ? -14.865  -1.469  13.085  1.00 65.14  ? 391 ILE D CA  1 
ATOM   15535 C C   . ILE D 1 331 ? -13.432  -1.041  12.707  1.00 59.92  ? 391 ILE D C   1 
ATOM   15536 O O   . ILE D 1 331 ? -12.496  -1.826  12.925  1.00 58.52  ? 391 ILE D O   1 
ATOM   15537 C CB  . ILE D 1 331 ? -15.699  -1.821  11.820  1.00 70.79  ? 391 ILE D CB  1 
ATOM   15538 C CG1 . ILE D 1 331 ? -17.178  -2.042  12.120  1.00 67.38  ? 391 ILE D CG1 1 
ATOM   15539 C CG2 . ILE D 1 331 ? -15.109  -2.996  11.043  1.00 70.35  ? 391 ILE D CG2 1 
ATOM   15540 C CD1 . ILE D 1 331 ? -17.504  -3.380  12.591  1.00 79.95  ? 391 ILE D CD1 1 
ATOM   15541 N N   . ALA D 1 332 ? -13.274  0.167   12.160  1.00 54.28  ? 392 ALA D N   1 
ATOM   15542 C CA  . ALA D 1 332 ? -11.987  0.691   11.641  1.00 52.49  ? 392 ALA D CA  1 
ATOM   15543 C C   . ALA D 1 332 ? -10.937  0.659   12.741  1.00 51.22  ? 392 ALA D C   1 
ATOM   15544 O O   . ALA D 1 332 ? -9.841   0.151   12.513  1.00 72.43  ? 392 ALA D O   1 
ATOM   15545 C CB  . ALA D 1 332 ? -12.163  2.096   11.129  1.00 55.67  ? 392 ALA D CB  1 
ATOM   15546 N N   . GLU D 1 333 ? -11.273  1.184   13.907  1.00 49.27  ? 393 GLU D N   1 
ATOM   15547 C CA  . GLU D 1 333 ? -10.346  1.289   15.053  1.00 49.51  ? 393 GLU D CA  1 
ATOM   15548 C C   . GLU D 1 333 ? -9.932   -0.111  15.499  1.00 47.35  ? 393 GLU D C   1 
ATOM   15549 O O   . GLU D 1 333 ? -8.792   -0.252  15.874  1.00 58.31  ? 393 GLU D O   1 
ATOM   15550 C CB  . GLU D 1 333 ? -11.007  2.063   16.189  1.00 55.70  ? 393 GLU D CB  1 
ATOM   15551 C CG  . GLU D 1 333 ? -10.067  2.370   17.338  1.00 72.68  ? 393 GLU D CG  1 
ATOM   15552 C CD  . GLU D 1 333 ? -8.905   3.290   17.014  1.00 72.50  ? 393 GLU D CD  1 
ATOM   15553 O OE1 . GLU D 1 333 ? -9.037   4.077   16.055  1.00 78.19  ? 393 GLU D OE1 1 
ATOM   15554 O OE2 . GLU D 1 333 ? -7.878   3.231   17.731  1.00 70.49  ? 393 GLU D OE2 1 
ATOM   15555 N N   . LEU D 1 334 ? -10.819  -1.102  15.465  1.00 48.25  ? 394 LEU D N   1 
ATOM   15556 C CA  . LEU D 1 334 ? -10.481  -2.486  15.887  1.00 53.43  ? 394 LEU D CA  1 
ATOM   15557 C C   . LEU D 1 334 ? -9.577   -3.130  14.837  1.00 52.23  ? 394 LEU D C   1 
ATOM   15558 O O   . LEU D 1 334 ? -8.802   -4.039  15.171  1.00 59.47  ? 394 LEU D O   1 
ATOM   15559 C CB  . LEU D 1 334 ? -11.735  -3.336  16.115  1.00 47.54  ? 394 LEU D CB  1 
ATOM   15560 C CG  . LEU D 1 334 ? -11.454  -4.583  16.942  1.00 50.54  ? 394 LEU D CG  1 
ATOM   15561 C CD1 . LEU D 1 334 ? -11.144  -4.197  18.384  1.00 54.25  ? 394 LEU D CD1 1 
ATOM   15562 C CD2 . LEU D 1 334 ? -12.570  -5.615  16.881  1.00 53.97  ? 394 LEU D CD2 1 
ATOM   15563 N N   . ILE D 1 335 ? -9.672   -2.690  13.602  1.00 56.40  ? 395 ILE D N   1 
ATOM   15564 C CA  . ILE D 1 335 ? -8.823   -3.247  12.515  1.00 66.03  ? 395 ILE D CA  1 
ATOM   15565 C C   . ILE D 1 335 ? -7.400   -2.711  12.722  1.00 63.65  ? 395 ILE D C   1 
ATOM   15566 O O   . ILE D 1 335 ? -6.477   -3.549  12.845  1.00 66.63  ? 395 ILE D O   1 
ATOM   15567 C CB  . ILE D 1 335 ? -9.430   -2.937  11.133  1.00 73.84  ? 395 ILE D CB  1 
ATOM   15568 C CG1 . ILE D 1 335 ? -10.793  -3.619  10.952  1.00 80.46  ? 395 ILE D CG1 1 
ATOM   15569 C CG2 . ILE D 1 335 ? -8.455   -3.358  10.061  1.00 80.67  ? 395 ILE D CG2 1 
ATOM   15570 C CD1 . ILE D 1 335 ? -11.446  -3.427  9.601   1.00 89.06  ? 395 ILE D CD1 1 
ATOM   15571 N N   . ALA D 1 336 ? -7.254   -1.382  12.804  1.00 60.22  ? 396 ALA D N   1 
ATOM   15572 C CA  . ALA D 1 336 ? -5.982   -0.649  13.018  1.00 50.14  ? 396 ALA D CA  1 
ATOM   15573 C C   . ALA D 1 336 ? -5.288   -1.206  14.270  1.00 49.22  ? 396 ALA D C   1 
ATOM   15574 O O   . ALA D 1 336 ? -4.074   -1.432  14.235  1.00 53.74  ? 396 ALA D O   1 
ATOM   15575 C CB  . ALA D 1 336 ? -6.235   0.841   13.122  1.00 46.96  ? 396 ALA D CB  1 
ATOM   15576 N N   . LEU D 1 337 ? -6.037   -1.454  15.339  1.00 51.16  ? 397 LEU D N   1 
ATOM   15577 C CA  . LEU D 1 337 ? -5.498   -2.044  16.596  1.00 53.79  ? 397 LEU D CA  1 
ATOM   15578 C C   . LEU D 1 337 ? -4.917   -3.434  16.285  1.00 56.33  ? 397 LEU D C   1 
ATOM   15579 O O   . LEU D 1 337 ? -3.747   -3.668  16.644  1.00 70.55  ? 397 LEU D O   1 
ATOM   15580 C CB  . LEU D 1 337 ? -6.649   -2.118  17.602  1.00 59.77  ? 397 LEU D CB  1 
ATOM   15581 C CG  . LEU D 1 337 ? -6.383   -2.303  19.086  1.00 60.63  ? 397 LEU D CG  1 
ATOM   15582 C CD1 . LEU D 1 337 ? -6.282   -3.756  19.491  1.00 63.39  ? 397 LEU D CD1 1 
ATOM   15583 C CD2 . LEU D 1 337 ? -5.198   -1.479  19.540  1.00 60.24  ? 397 LEU D CD2 1 
ATOM   15584 N N   . GLU D 1 338 ? -5.659   -4.316  15.612  1.00 47.51  ? 398 GLU D N   1 
ATOM   15585 C CA  . GLU D 1 338 ? -5.177   -5.686  15.320  1.00 48.41  ? 398 GLU D CA  1 
ATOM   15586 C C   . GLU D 1 338 ? -3.895   -5.607  14.499  1.00 50.89  ? 398 GLU D C   1 
ATOM   15587 O O   . GLU D 1 338 ? -3.017   -6.455  14.713  1.00 54.28  ? 398 GLU D O   1 
ATOM   15588 C CB  . GLU D 1 338 ? -6.248   -6.493  14.576  1.00 52.71  ? 398 GLU D CB  1 
ATOM   15589 C CG  . GLU D 1 338 ? -5.879   -7.933  14.300  1.00 47.47  ? 398 GLU D CG  1 
ATOM   15590 C CD  . GLU D 1 338 ? -5.119   -8.605  15.421  1.00 52.04  ? 398 GLU D CD  1 
ATOM   15591 O OE1 . GLU D 1 338 ? -5.498   -8.461  16.579  1.00 59.09  ? 398 GLU D OE1 1 
ATOM   15592 O OE2 . GLU D 1 338 ? -4.099   -9.175  15.137  1.00 62.48  ? 398 GLU D OE2 1 
ATOM   15593 N N   . ILE D 1 339 ? -3.799   -4.621  13.593  1.00 59.35  ? 399 ILE D N   1 
ATOM   15594 C CA  . ILE D 1 339 ? -2.591   -4.336  12.742  1.00 62.75  ? 399 ILE D CA  1 
ATOM   15595 C C   . ILE D 1 339 ? -1.420   -3.946  13.649  1.00 58.23  ? 399 ILE D C   1 
ATOM   15596 O O   . ILE D 1 339 ? -0.349   -4.571  13.517  1.00 73.90  ? 399 ILE D O   1 
ATOM   15597 C CB  . ILE D 1 339 ? -2.873   -3.248  11.677  1.00 66.82  ? 399 ILE D CB  1 
ATOM   15598 C CG1 . ILE D 1 339 ? -3.732   -3.783  10.521  1.00 71.34  ? 399 ILE D CG1 1 
ATOM   15599 C CG2 . ILE D 1 339 ? -1.591   -2.632  11.154  1.00 65.70  ? 399 ILE D CG2 1 
ATOM   15600 C CD1 . ILE D 1 339 ? -4.191   -2.708  9.534   1.00 65.18  ? 399 ILE D CD1 1 
ATOM   15601 N N   . SER D 1 340 ? -1.625   -2.987  14.549  1.00 52.15  ? 400 SER D N   1 
ATOM   15602 C CA  . SER D 1 340 ? -0.613   -2.545  15.541  1.00 60.32  ? 400 SER D CA  1 
ATOM   15603 C C   . SER D 1 340 ? -0.086   -3.750  16.336  1.00 62.58  ? 400 SER D C   1 
ATOM   15604 O O   . SER D 1 340 ? 1.107    -3.783  16.612  1.00 69.19  ? 400 SER D O   1 
ATOM   15605 C CB  . SER D 1 340 ? -1.146   -1.480  16.459  1.00 65.32  ? 400 SER D CB  1 
ATOM   15606 O OG  . SER D 1 340 ? -1.031   -0.176  15.889  1.00 75.64  ? 400 SER D OG  1 
ATOM   15607 N N   . LYS D 1 341 ? -0.930   -4.723  16.687  1.00 70.35  ? 401 LYS D N   1 
ATOM   15608 C CA  . LYS D 1 341 ? -0.494   -5.904  17.487  1.00 78.13  ? 401 LYS D CA  1 
ATOM   15609 C C   . LYS D 1 341 ? 0.269    -6.876  16.570  1.00 71.68  ? 401 LYS D C   1 
ATOM   15610 O O   . LYS D 1 341 ? 1.101    -7.629  17.075  1.00 75.54  ? 401 LYS D O   1 
ATOM   15611 C CB  . LYS D 1 341 ? -1.676   -6.517  18.267  1.00 79.07  ? 401 LYS D CB  1 
ATOM   15612 C CG  . LYS D 1 341 ? -1.945   -5.966  19.675  1.00 85.77  ? 401 LYS D CG  1 
ATOM   15613 C CD  . LYS D 1 341 ? -1.198   -4.661  19.977  1.00 111.01 ? 401 LYS D CD  1 
ATOM   15614 C CE  . LYS D 1 341 ? -1.637   -3.950  21.237  1.00 108.90 ? 401 LYS D CE  1 
ATOM   15615 N NZ  . LYS D 1 341 ? -2.650   -2.910  20.941  1.00 122.79 ? 401 LYS D NZ  1 
ATOM   15616 N N   . GLN D 1 342 ? 0.044    -6.830  15.265  1.00 67.45  ? 402 GLN D N   1 
ATOM   15617 C CA  . GLN D 1 342 ? 0.656    -7.789  14.313  1.00 73.52  ? 402 GLN D CA  1 
ATOM   15618 C C   . GLN D 1 342 ? 1.956    -7.222  13.721  1.00 65.46  ? 402 GLN D C   1 
ATOM   15619 O O   . GLN D 1 342 ? 2.837    -8.016  13.332  1.00 62.43  ? 402 GLN D O   1 
ATOM   15620 C CB  . GLN D 1 342 ? -0.384   -8.082  13.231  1.00 79.49  ? 402 GLN D CB  1 
ATOM   15621 C CG  . GLN D 1 342 ? -0.270   -9.443  12.571  1.00 85.65  ? 402 GLN D CG  1 
ATOM   15622 C CD  . GLN D 1 342 ? -1.640   -10.043 12.389  1.00 85.95  ? 402 GLN D CD  1 
ATOM   15623 O OE1 . GLN D 1 342 ? -2.301   -10.308 13.383  1.00 88.63  ? 402 GLN D OE1 1 
ATOM   15624 N NE2 . GLN D 1 342 ? -2.079   -10.228 11.145  1.00 86.57  ? 402 GLN D NE2 1 
ATOM   15625 N N   . THR D 1 343 ? 2.068    -5.899  13.646  1.00 59.26  ? 403 THR D N   1 
ATOM   15626 C CA  . THR D 1 343 ? 3.196    -5.192  12.988  1.00 57.22  ? 403 THR D CA  1 
ATOM   15627 C C   . THR D 1 343 ? 4.087    -4.508  14.020  1.00 52.86  ? 403 THR D C   1 
ATOM   15628 O O   . THR D 1 343 ? 5.257    -4.320  13.739  1.00 68.40  ? 403 THR D O   1 
ATOM   15629 C CB  . THR D 1 343 ? 2.708    -4.123  12.010  1.00 58.86  ? 403 THR D CB  1 
ATOM   15630 O OG1 . THR D 1 343 ? 2.051    -3.107  12.785  1.00 50.06  ? 403 THR D OG1 1 
ATOM   15631 C CG2 . THR D 1 343 ? 1.853    -4.712  10.907  1.00 61.03  ? 403 THR D CG2 1 
ATOM   15632 N N   . ASN D 1 344 ? 3.532    -4.145  15.156  1.00 57.65  ? 404 ASN D N   1 
ATOM   15633 C CA  . ASN D 1 344 ? 4.216    -3.369  16.227  1.00 67.55  ? 404 ASN D CA  1 
ATOM   15634 C C   . ASN D 1 344 ? 4.410    -1.918  15.758  1.00 60.61  ? 404 ASN D C   1 
ATOM   15635 O O   . ASN D 1 344 ? 5.203    -1.182  16.331  1.00 63.42  ? 404 ASN D O   1 
ATOM   15636 C CB  . ASN D 1 344 ? 5.486    -4.046  16.717  1.00 65.50  ? 404 ASN D CB  1 
ATOM   15637 C CG  . ASN D 1 344 ? 5.718    -3.667  18.162  1.00 80.22  ? 404 ASN D CG  1 
ATOM   15638 O OD1 . ASN D 1 344 ? 5.822    -2.488  18.523  1.00 83.96  ? 404 ASN D OD1 1 
ATOM   15639 N ND2 . ASN D 1 344 ? 5.719    -4.683  19.010  1.00 97.86  ? 404 ASN D ND2 1 
ATOM   15640 N N   . ALA D 1 345 ? 3.631    -1.503  14.776  1.00 54.95  ? 405 ALA D N   1 
ATOM   15641 C CA  . ALA D 1 345 ? 3.709    -0.158  14.203  1.00 62.52  ? 405 ALA D CA  1 
ATOM   15642 C C   . ALA D 1 345 ? 2.974    0.815   15.116  1.00 69.42  ? 405 ALA D C   1 
ATOM   15643 O O   . ALA D 1 345 ? 2.099    0.411   15.885  1.00 64.40  ? 405 ALA D O   1 
ATOM   15644 C CB  . ALA D 1 345 ? 3.125    -0.206  12.819  1.00 60.00  ? 405 ALA D CB  1 
ATOM   15645 N N   . PRO D 1 346 ? 3.319    2.127   15.053  1.00 80.41  ? 406 PRO D N   1 
ATOM   15646 C CA  . PRO D 1 346 ? 2.497    3.181   15.648  1.00 85.34  ? 406 PRO D CA  1 
ATOM   15647 C C   . PRO D 1 346 ? 1.074    3.175   15.055  1.00 81.48  ? 406 PRO D C   1 
ATOM   15648 O O   . PRO D 1 346 ? 0.904    2.849   13.903  1.00 83.16  ? 406 PRO D O   1 
ATOM   15649 C CB  . PRO D 1 346 ? 3.237    4.499   15.319  1.00 87.67  ? 406 PRO D CB  1 
ATOM   15650 C CG  . PRO D 1 346 ? 4.185    4.146   14.184  1.00 85.78  ? 406 PRO D CG  1 
ATOM   15651 C CD  . PRO D 1 346 ? 4.512    2.677   14.386  1.00 83.63  ? 406 PRO D CD  1 
ATOM   15652 N N   . ILE D 1 347 ? 0.093    3.544   15.871  1.00 84.82  ? 407 ILE D N   1 
ATOM   15653 C CA  . ILE D 1 347 ? -1.340   3.356   15.534  1.00 83.09  ? 407 ILE D CA  1 
ATOM   15654 C C   . ILE D 1 347 ? -1.631   4.161   14.261  1.00 89.23  ? 407 ILE D C   1 
ATOM   15655 O O   . ILE D 1 347 ? -2.229   3.547   13.350  1.00 98.83  ? 407 ILE D O   1 
ATOM   15656 C CB  . ILE D 1 347 ? -2.245   3.684   16.740  1.00 89.10  ? 407 ILE D CB  1 
ATOM   15657 C CG1 . ILE D 1 347 ? -3.626   3.035   16.614  1.00 90.42  ? 407 ILE D CG1 1 
ATOM   15658 C CG2 . ILE D 1 347 ? -2.359   5.187   16.972  1.00 93.48  ? 407 ILE D CG2 1 
ATOM   15659 C CD1 . ILE D 1 347 ? -3.634   1.521   16.454  1.00 85.07  ? 407 ILE D CD1 1 
ATOM   15660 N N   . GLU D 1 348 ? -1.157   5.414   14.129  1.00 82.88  ? 408 GLU D N   1 
ATOM   15661 C CA  . GLU D 1 348 ? -1.546   6.244   12.945  1.00 97.65  ? 408 GLU D CA  1 
ATOM   15662 C C   . GLU D 1 348 ? -0.892   5.739   11.652  1.00 99.91  ? 408 GLU D C   1 
ATOM   15663 O O   . GLU D 1 348 ? -1.392   6.169   10.586  1.00 102.54 ? 408 GLU D O   1 
ATOM   15664 C CB  . GLU D 1 348 ? -1.279   7.731   13.117  1.00 103.86 ? 408 GLU D CB  1 
ATOM   15665 C CG  . GLU D 1 348 ? 0.110    8.037   13.592  1.00 129.59 ? 408 GLU D CG  1 
ATOM   15666 C CD  . GLU D 1 348 ? 0.426    9.510   13.440  1.00 152.12 ? 408 GLU D CD  1 
ATOM   15667 O OE1 . GLU D 1 348 ? 0.627    10.171  14.474  1.00 197.84 ? 408 GLU D OE1 1 
ATOM   15668 O OE2 . GLU D 1 348 ? 0.449    9.990   12.289  1.00 162.52 ? 408 GLU D OE2 1 
ATOM   15669 N N   . GLU D 1 349 ? 0.091    4.821   11.713  1.00 102.98 ? 409 GLU D N   1 
ATOM   15670 C CA  . GLU D 1 349 ? 0.588    4.104   10.504  1.00 103.17 ? 409 GLU D CA  1 
ATOM   15671 C C   . GLU D 1 349 ? -0.405   2.991   10.157  1.00 94.14  ? 409 GLU D C   1 
ATOM   15672 O O   . GLU D 1 349 ? -0.523   2.691   8.941   1.00 118.07 ? 409 GLU D O   1 
ATOM   15673 C CB  . GLU D 1 349 ? 1.997    3.525   10.685  1.00 117.79 ? 409 GLU D CB  1 
ATOM   15674 C CG  . GLU D 1 349 ? 2.626    2.935   9.404   1.00 123.90 ? 409 GLU D CG  1 
ATOM   15675 C CD  . GLU D 1 349 ? 2.358    1.476   8.976   1.00 130.50 ? 409 GLU D CD  1 
ATOM   15676 O OE1 . GLU D 1 349 ? 2.542    1.161   7.779   1.00 116.71 ? 409 GLU D OE1 1 
ATOM   15677 O OE2 . GLU D 1 349 ? 1.948    0.638   9.813   1.00 133.23 ? 409 GLU D OE2 1 
ATOM   15678 N N   . CYS D 1 350 ? -1.140   2.465   11.153  1.00 74.06  ? 410 CYS D N   1 
ATOM   15679 C CA  . CYS D 1 350 ? -2.141   1.379   10.936  1.00 72.20  ? 410 CYS D CA  1 
ATOM   15680 C C   . CYS D 1 350 ? -3.443   1.944   10.300  1.00 71.40  ? 410 CYS D C   1 
ATOM   15681 O O   . CYS D 1 350 ? -4.142   1.147   9.601   1.00 57.93  ? 410 CYS D O   1 
ATOM   15682 C CB  . CYS D 1 350 ? -2.331   0.586   12.226  1.00 66.50  ? 410 CYS D CB  1 
ATOM   15683 S SG  . CYS D 1 350 ? -0.784   -0.013  12.983  1.00 55.57  ? 410 CYS D SG  1 
ATOM   15684 N N   . ARG D 1 351 ? -3.704   3.255   10.443  1.00 64.85  ? 411 ARG D N   1 
ATOM   15685 C CA  . ARG D 1 351 ? -4.904   3.935   9.879   1.00 65.66  ? 411 ARG D CA  1 
ATOM   15686 C C   . ARG D 1 351 ? -4.678   4.493   8.463   1.00 60.19  ? 411 ARG D C   1 
ATOM   15687 O O   . ARG D 1 351 ? -5.680   4.934   7.837   1.00 63.94  ? 411 ARG D O   1 
ATOM   15688 C CB  . ARG D 1 351 ? -5.372   5.104   10.750  1.00 68.09  ? 411 ARG D CB  1 
ATOM   15689 C CG  . ARG D 1 351 ? -5.568   4.749   12.220  1.00 74.61  ? 411 ARG D CG  1 
ATOM   15690 C CD  . ARG D 1 351 ? -6.358   5.840   12.968  1.00 69.84  ? 411 ARG D CD  1 
ATOM   15691 N NE  . ARG D 1 351 ? -5.761   6.227   14.257  1.00 66.10  ? 411 ARG D NE  1 
ATOM   15692 C CZ  . ARG D 1 351 ? -6.131   5.770   15.444  1.00 70.30  ? 411 ARG D CZ  1 
ATOM   15693 N NH1 . ARG D 1 351 ? -7.125   4.917   15.560  1.00 90.75  ? 411 ARG D NH1 1 
ATOM   15694 N NH2 . ARG D 1 351 ? -5.548   6.188   16.541  1.00 71.02  ? 411 ARG D NH2 1 
ATOM   15695 N N   . LYS D 1 352 ? -3.442   4.511   7.973   1.00 66.56  ? 412 LYS D N   1 
ATOM   15696 C CA  . LYS D 1 352 ? -3.100   5.252   6.721   1.00 72.84  ? 412 LYS D CA  1 
ATOM   15697 C C   . LYS D 1 352 ? -3.881   4.644   5.537   1.00 68.35  ? 412 LYS D C   1 
ATOM   15698 O O   . LYS D 1 352 ? -4.214   5.406   4.645   1.00 72.11  ? 412 LYS D O   1 
ATOM   15699 C CB  . LYS D 1 352 ? -1.581   5.277   6.469   1.00 83.27  ? 412 LYS D CB  1 
ATOM   15700 C CG  . LYS D 1 352 ? -0.923   3.941   6.078   1.00 97.63  ? 412 LYS D CG  1 
ATOM   15701 C CD  . LYS D 1 352 ? 0.211    3.968   5.013   1.00 91.59  ? 412 LYS D CD  1 
ATOM   15702 C CE  . LYS D 1 352 ? 1.619    4.140   5.559   1.00 95.36  ? 412 LYS D CE  1 
ATOM   15703 N NZ  . LYS D 1 352 ? 1.720    5.295   6.486   1.00 104.70 ? 412 LYS D NZ  1 
ATOM   15704 N N   . LYS D 1 353 ? -4.181   3.339   5.527   1.00 61.69  ? 413 LYS D N   1 
ATOM   15705 C CA  . LYS D 1 353 ? -4.843   2.638   4.385   1.00 61.51  ? 413 LYS D CA  1 
ATOM   15706 C C   . LYS D 1 353 ? -6.321   2.318   4.703   1.00 62.35  ? 413 LYS D C   1 
ATOM   15707 O O   . LYS D 1 353 ? -6.923   1.421   4.026   1.00 70.17  ? 413 LYS D O   1 
ATOM   15708 C CB  . LYS D 1 353 ? -4.024   1.400   4.002   1.00 71.93  ? 413 LYS D CB  1 
ATOM   15709 C CG  . LYS D 1 353 ? -2.655   1.763   3.452   1.00 73.21  ? 413 LYS D CG  1 
ATOM   15710 C CD  . LYS D 1 353 ? -1.718   0.623   3.409   1.00 82.36  ? 413 LYS D CD  1 
ATOM   15711 C CE  . LYS D 1 353 ? -1.927   -0.196  2.162   1.00 85.36  ? 413 LYS D CE  1 
ATOM   15712 N NZ  . LYS D 1 353 ? -1.123   -1.436  2.236   1.00 88.86  ? 413 LYS D NZ  1 
ATOM   15713 N N   . VAL D 1 354 ? -6.931   3.061   5.636   1.00 56.69  ? 414 VAL D N   1 
ATOM   15714 C CA  . VAL D 1 354 ? -8.366   2.932   6.023   1.00 56.22  ? 414 VAL D CA  1 
ATOM   15715 C C   . VAL D 1 354 ? -9.044   4.278   5.769   1.00 60.94  ? 414 VAL D C   1 
ATOM   15716 O O   . VAL D 1 354 ? -8.634   5.289   6.407   1.00 57.31  ? 414 VAL D O   1 
ATOM   15717 C CB  . VAL D 1 354 ? -8.510   2.499   7.489   1.00 63.47  ? 414 VAL D CB  1 
ATOM   15718 C CG1 . VAL D 1 354 ? -9.961   2.433   7.941   1.00 59.36  ? 414 VAL D CG1 1 
ATOM   15719 C CG2 . VAL D 1 354 ? -7.802   1.179   7.746   1.00 68.39  ? 414 VAL D CG2 1 
ATOM   15720 N N   . TRP D 1 355 ? -10.051  4.269   4.885   1.00 65.20  ? 415 TRP D N   1 
ATOM   15721 C CA  . TRP D 1 355 ? -10.796  5.456   4.393   1.00 65.62  ? 415 TRP D CA  1 
ATOM   15722 C C   . TRP D 1 355 ? -12.291  5.262   4.641   1.00 68.27  ? 415 TRP D C   1 
ATOM   15723 O O   . TRP D 1 355 ? -12.815  4.220   4.210   1.00 67.85  ? 415 TRP D O   1 
ATOM   15724 C CB  . TRP D 1 355 ? -10.555  5.632   2.904   1.00 61.09  ? 415 TRP D CB  1 
ATOM   15725 C CG  . TRP D 1 355 ? -9.117   5.695   2.507   1.00 59.66  ? 415 TRP D CG  1 
ATOM   15726 C CD1 . TRP D 1 355 ? -8.267   4.649   2.263   1.00 59.79  ? 415 TRP D CD1 1 
ATOM   15727 C CD2 . TRP D 1 355 ? -8.375   6.895   2.240   1.00 60.01  ? 415 TRP D CD2 1 
ATOM   15728 N NE1 . TRP D 1 355 ? -7.045   5.122   1.856   1.00 56.71  ? 415 TRP D NE1 1 
ATOM   15729 C CE2 . TRP D 1 355 ? -7.090   6.489   1.815   1.00 54.53  ? 415 TRP D CE2 1 
ATOM   15730 C CE3 . TRP D 1 355 ? -8.684   8.262   2.289   1.00 56.46  ? 415 TRP D CE3 1 
ATOM   15731 C CZ2 . TRP D 1 355 ? -6.116   7.409   1.467   1.00 57.24  ? 415 TRP D CZ2 1 
ATOM   15732 C CZ3 . TRP D 1 355 ? -7.711   9.171   1.951   1.00 53.37  ? 415 TRP D CZ3 1 
ATOM   15733 C CH2 . TRP D 1 355 ? -6.448   8.747   1.547   1.00 61.80  ? 415 TRP D CH2 1 
ATOM   15734 N N   . LEU D 1 356 ? -12.956  6.263   5.223   1.00 73.66  ? 416 LEU D N   1 
ATOM   15735 C CA  . LEU D 1 356 ? -14.426  6.250   5.434   1.00 68.51  ? 416 LEU D CA  1 
ATOM   15736 C C   . LEU D 1 356 ? -15.068  7.366   4.601   1.00 69.70  ? 416 LEU D C   1 
ATOM   15737 O O   . LEU D 1 356 ? -14.435  8.440   4.436   1.00 62.13  ? 416 LEU D O   1 
ATOM   15738 C CB  . LEU D 1 356 ? -14.739  6.398   6.919   1.00 69.31  ? 416 LEU D CB  1 
ATOM   15739 C CG  . LEU D 1 356 ? -14.298  5.201   7.758   1.00 78.58  ? 416 LEU D CG  1 
ATOM   15740 C CD1 . LEU D 1 356 ? -12.905  5.431   8.305   1.00 87.02  ? 416 LEU D CD1 1 
ATOM   15741 C CD2 . LEU D 1 356 ? -15.269  4.896   8.888   1.00 84.52  ? 416 LEU D CD2 1 
ATOM   15742 N N   . VAL D 1 357 ? -16.256  7.064   4.063   1.00 60.20  ? 417 VAL D N   1 
ATOM   15743 C CA  . VAL D 1 357 ? -17.131  7.992   3.305   1.00 56.18  ? 417 VAL D CA  1 
ATOM   15744 C C   . VAL D 1 357 ? -18.448  8.145   4.070   1.00 60.36  ? 417 VAL D C   1 
ATOM   15745 O O   . VAL D 1 357 ? -19.201  7.135   4.240   1.00 49.67  ? 417 VAL D O   1 
ATOM   15746 C CB  . VAL D 1 357 ? -17.396  7.492   1.881   1.00 68.37  ? 417 VAL D CB  1 
ATOM   15747 C CG1 . VAL D 1 357 ? -18.257  8.481   1.097   1.00 68.49  ? 417 VAL D CG1 1 
ATOM   15748 C CG2 . VAL D 1 357 ? -16.104  7.187   1.143   1.00 78.16  ? 417 VAL D CG2 1 
ATOM   15749 N N   . ASP D 1 358 ? -18.723  9.383   4.475   1.00 57.82  ? 418 ASP D N   1 
ATOM   15750 C CA  . ASP D 1 358 ? -19.953  9.783   5.188   1.00 56.60  ? 418 ASP D CA  1 
ATOM   15751 C C   . ASP D 1 358 ? -20.898  10.472  4.202   1.00 60.45  ? 418 ASP D C   1 
ATOM   15752 O O   . ASP D 1 358 ? -20.648  10.437  2.982   1.00 48.40  ? 418 ASP D O   1 
ATOM   15753 C CB  . ASP D 1 358 ? -19.600  10.694  6.365   1.00 64.86  ? 418 ASP D CB  1 
ATOM   15754 C CG  . ASP D 1 358 ? -19.008  12.030  5.940   1.00 72.49  ? 418 ASP D CG  1 
ATOM   15755 O OD1 . ASP D 1 358 ? -19.265  12.449  4.798   1.00 68.97  ? 418 ASP D OD1 1 
ATOM   15756 O OD2 . ASP D 1 358 ? -18.247  12.624  6.739   1.00 71.79  ? 418 ASP D OD2 1 
ATOM   15757 N N   . SER D 1 359 ? -21.952  11.080  4.752   1.00 77.78  ? 419 SER D N   1 
ATOM   15758 C CA  . SER D 1 359 ? -22.978  11.921  4.080   1.00 73.82  ? 419 SER D CA  1 
ATOM   15759 C C   . SER D 1 359 ? -22.338  13.006  3.204   1.00 62.50  ? 419 SER D C   1 
ATOM   15760 O O   . SER D 1 359 ? -22.844  13.212  2.108   1.00 69.94  ? 419 SER D O   1 
ATOM   15761 C CB  . SER D 1 359 ? -23.931  12.517  5.113   1.00 76.29  ? 419 SER D CB  1 
ATOM   15762 O OG  . SER D 1 359 ? -23.405  12.430  6.446   1.00 71.08  ? 419 SER D OG  1 
ATOM   15763 N N   . LYS D 1 360 ? -21.265  13.651  3.657   1.00 64.15  ? 420 LYS D N   1 
ATOM   15764 C CA  . LYS D 1 360 ? -20.636  14.824  2.977   1.00 70.31  ? 420 LYS D CA  1 
ATOM   15765 C C   . LYS D 1 360 ? -19.567  14.327  1.983   1.00 64.75  ? 420 LYS D C   1 
ATOM   15766 O O   . LYS D 1 360 ? -19.036  15.169  1.232   1.00 63.74  ? 420 LYS D O   1 
ATOM   15767 C CB  . LYS D 1 360 ? -20.024  15.814  3.982   1.00 88.36  ? 420 LYS D CB  1 
ATOM   15768 C CG  . LYS D 1 360 ? -20.918  16.302  5.122   1.00 101.33 ? 420 LYS D CG  1 
ATOM   15769 C CD  . LYS D 1 360 ? -20.877  15.405  6.371   1.00 132.96 ? 420 LYS D CD  1 
ATOM   15770 C CE  . LYS D 1 360 ? -21.617  15.921  7.595   1.00 128.85 ? 420 LYS D CE  1 
ATOM   15771 N NZ  . LYS D 1 360 ? -22.021  14.806  8.492   1.00 120.78 ? 420 LYS D NZ  1 
ATOM   15772 N N   . GLY D 1 361 ? -19.258  13.017  1.963   1.00 59.40  ? 421 GLY D N   1 
ATOM   15773 C CA  . GLY D 1 361 ? -18.323  12.369  1.016   1.00 49.45  ? 421 GLY D CA  1 
ATOM   15774 C C   . GLY D 1 361 ? -17.137  11.718  1.713   1.00 52.79  ? 421 GLY D C   1 
ATOM   15775 O O   . GLY D 1 361 ? -17.264  11.331  2.896   1.00 56.47  ? 421 GLY D O   1 
ATOM   15776 N N   . LEU D 1 362 ? -16.007  11.591  1.008   1.00 54.50  ? 422 LEU D N   1 
ATOM   15777 C CA  . LEU D 1 362 ? -14.753  11.005  1.542   1.00 53.68  ? 422 LEU D CA  1 
ATOM   15778 C C   . LEU D 1 362 ? -14.224  11.927  2.625   1.00 55.91  ? 422 LEU D C   1 
ATOM   15779 O O   . LEU D 1 362 ? -14.114  13.142  2.384   1.00 56.22  ? 422 LEU D O   1 
ATOM   15780 C CB  . LEU D 1 362 ? -13.710  10.837  0.435   1.00 57.17  ? 422 LEU D CB  1 
ATOM   15781 C CG  . LEU D 1 362 ? -12.391  10.181  0.862   1.00 60.36  ? 422 LEU D CG  1 
ATOM   15782 C CD1 . LEU D 1 362 ? -12.629  8.749   1.356   1.00 59.63  ? 422 LEU D CD1 1 
ATOM   15783 C CD2 . LEU D 1 362 ? -11.360  10.221  -0.264  1.00 53.28  ? 422 LEU D CD2 1 
ATOM   15784 N N   . ILE D 1 363 ? -13.947  11.346  3.791   1.00 69.03  ? 423 ILE D N   1 
ATOM   15785 C CA  . ILE D 1 363 ? -13.337  12.062  4.948   1.00 71.28  ? 423 ILE D CA  1 
ATOM   15786 C C   . ILE D 1 363 ? -11.862  12.305  4.608   1.00 70.21  ? 423 ILE D C   1 
ATOM   15787 O O   . ILE D 1 363 ? -11.086  11.333  4.463   1.00 65.91  ? 423 ILE D O   1 
ATOM   15788 C CB  . ILE D 1 363 ? -13.572  11.307  6.272   1.00 71.36  ? 423 ILE D CB  1 
ATOM   15789 C CG1 . ILE D 1 363 ? -15.067  11.214  6.596   1.00 71.47  ? 423 ILE D CG1 1 
ATOM   15790 C CG2 . ILE D 1 363 ? -12.848  11.983  7.406   1.00 65.83  ? 423 ILE D CG2 1 
ATOM   15791 C CD1 . ILE D 1 363 ? -15.469  9.954   7.282   1.00 72.16  ? 423 ILE D CD1 1 
ATOM   15792 N N   . VAL D 1 364 ? -11.532  13.582  4.449   1.00 74.27  ? 424 VAL D N   1 
ATOM   15793 C CA  . VAL D 1 364 ? -10.200  14.101  4.053   1.00 66.48  ? 424 VAL D CA  1 
ATOM   15794 C C   . VAL D 1 364 ? -9.847   15.236  5.019   1.00 72.34  ? 424 VAL D C   1 
ATOM   15795 O O   . VAL D 1 364 ? -10.776  15.873  5.565   1.00 68.29  ? 424 VAL D O   1 
ATOM   15796 C CB  . VAL D 1 364 ? -10.210  14.563  2.590   1.00 66.88  ? 424 VAL D CB  1 
ATOM   15797 C CG1 . VAL D 1 364 ? -10.222  13.369  1.643   1.00 69.19  ? 424 VAL D CG1 1 
ATOM   15798 C CG2 . VAL D 1 364 ? -11.354  15.534  2.301   1.00 67.11  ? 424 VAL D CG2 1 
ATOM   15799 N N   . ASP D 1 365 ? -8.546   15.463  5.220   1.00 83.76  ? 425 ASP D N   1 
ATOM   15800 C CA  . ASP D 1 365 ? -7.990   16.448  6.184   1.00 97.12  ? 425 ASP D CA  1 
ATOM   15801 C C   . ASP D 1 365 ? -8.359   17.868  5.716   1.00 89.88  ? 425 ASP D C   1 
ATOM   15802 O O   . ASP D 1 365 ? -8.617   18.720  6.581   1.00 85.23  ? 425 ASP D O   1 
ATOM   15803 C CB  . ASP D 1 365 ? -6.490   16.198  6.409   1.00 116.70 ? 425 ASP D CB  1 
ATOM   15804 C CG  . ASP D 1 365 ? -5.624   17.451  6.439   1.00 131.34 ? 425 ASP D CG  1 
ATOM   15805 O OD1 . ASP D 1 365 ? -5.777   18.270  5.508   1.00 139.57 ? 425 ASP D OD1 1 
ATOM   15806 O OD2 . ASP D 1 365 ? -4.818   17.607  7.393   1.00 114.16 ? 425 ASP D OD2 1 
ATOM   15807 N N   . SER D 1 366 ? -8.412   18.126  4.409   1.00 89.98  ? 426 SER D N   1 
ATOM   15808 C CA  . SER D 1 366 ? -8.787   19.450  3.836   1.00 97.42  ? 426 SER D CA  1 
ATOM   15809 C C   . SER D 1 366 ? -10.170  19.887  4.340   1.00 85.07  ? 426 SER D C   1 
ATOM   15810 O O   . SER D 1 366 ? -10.480  21.082  4.231   1.00 78.62  ? 426 SER D O   1 
ATOM   15811 C CB  . SER D 1 366 ? -8.736   19.427  2.335   1.00 102.19 ? 426 SER D CB  1 
ATOM   15812 O OG  . SER D 1 366 ? -9.680   18.504  1.823   1.00 105.04 ? 426 SER D OG  1 
ATOM   15813 N N   . ARG D 1 367 ? -10.959  18.958  4.886   1.00 92.83  ? 427 ARG D N   1 
ATOM   15814 C CA  . ARG D 1 367 ? -12.349  19.203  5.361   1.00 112.91 ? 427 ARG D CA  1 
ATOM   15815 C C   . ARG D 1 367 ? -12.415  19.347  6.897   1.00 124.52 ? 427 ARG D C   1 
ATOM   15816 O O   . ARG D 1 367 ? -13.530  19.582  7.419   1.00 142.70 ? 427 ARG D O   1 
ATOM   15817 C CB  . ARG D 1 367 ? -13.238  18.043  4.902   1.00 107.15 ? 427 ARG D CB  1 
ATOM   15818 C CG  . ARG D 1 367 ? -14.618  18.454  4.407   1.00 93.68  ? 427 ARG D CG  1 
ATOM   15819 C CD  . ARG D 1 367 ? -15.317  17.228  3.872   1.00 78.03  ? 427 ARG D CD  1 
ATOM   15820 N NE  . ARG D 1 367 ? -15.902  16.476  4.965   1.00 78.04  ? 427 ARG D NE  1 
ATOM   15821 C CZ  . ARG D 1 367 ? -16.214  15.180  4.930   1.00 80.94  ? 427 ARG D CZ  1 
ATOM   15822 N NH1 . ARG D 1 367 ? -15.974  14.447  3.853   1.00 82.75  ? 427 ARG D NH1 1 
ATOM   15823 N NH2 . ARG D 1 367 ? -16.761  14.620  5.990   1.00 74.26  ? 427 ARG D NH2 1 
ATOM   15824 N N   . LYS D 1 368 ? -11.287  19.210  7.603   1.00 136.85 ? 428 LYS D N   1 
ATOM   15825 C CA  . LYS D 1 368 ? -11.238  19.000  9.078   1.00 122.73 ? 428 LYS D CA  1 
ATOM   15826 C C   . LYS D 1 368 ? -11.409  20.326  9.834   1.00 135.12 ? 428 LYS D C   1 
ATOM   15827 O O   . LYS D 1 368 ? -11.643  20.255  11.067  1.00 118.44 ? 428 LYS D O   1 
ATOM   15828 C CB  . LYS D 1 368 ? -9.933   18.297  9.459   1.00 107.46 ? 428 LYS D CB  1 
ATOM   15829 C CG  . LYS D 1 368 ? -9.877   17.787  10.888  1.00 114.65 ? 428 LYS D CG  1 
ATOM   15830 C CD  . LYS D 1 368 ? -8.480   17.429  11.331  1.00 121.53 ? 428 LYS D CD  1 
ATOM   15831 C CE  . LYS D 1 368 ? -7.960   16.182  10.642  1.00 118.96 ? 428 LYS D CE  1 
ATOM   15832 N NZ  . LYS D 1 368 ? -6.596   15.820  11.084  1.00 114.64 ? 428 LYS D NZ  1 
ATOM   15833 N N   . GLY D 1 369 ? -11.351  21.480  9.140   1.00 139.56 ? 429 GLY D N   1 
ATOM   15834 C CA  . GLY D 1 369 ? -11.669  22.829  9.662   1.00 117.82 ? 429 GLY D CA  1 
ATOM   15835 C C   . GLY D 1 369 ? -13.124  22.993  10.100  1.00 118.48 ? 429 GLY D C   1 
ATOM   15836 O O   . GLY D 1 369 ? -13.474  24.118  10.498  1.00 120.95 ? 429 GLY D O   1 
ATOM   15837 N N   . SER D 1 370 ? -13.940  21.931  10.006  1.00 119.54 ? 430 SER D N   1 
ATOM   15838 C CA  . SER D 1 370 ? -15.273  21.774  10.662  1.00 117.26 ? 430 SER D CA  1 
ATOM   15839 C C   . SER D 1 370 ? -15.742  20.310  10.515  1.00 113.17 ? 430 SER D C   1 
ATOM   15840 O O   . SER D 1 370 ? -16.783  20.043  9.885   1.00 108.97 ? 430 SER D O   1 
ATOM   15841 C CB  . SER D 1 370 ? -16.280  22.775  10.151  1.00 115.61 ? 430 SER D CB  1 
ATOM   15842 O OG  . SER D 1 370 ? -16.206  22.913  8.743   1.00 121.15 ? 430 SER D OG  1 
ATOM   15843 N N   . LEU D 1 371 ? -15.005  19.392  11.139  1.00 107.59 ? 431 LEU D N   1 
ATOM   15844 C CA  . LEU D 1 371 ? -15.312  17.934  11.169  1.00 106.72 ? 431 LEU D CA  1 
ATOM   15845 C C   . LEU D 1 371 ? -15.898  17.540  12.523  1.00 94.78  ? 431 LEU D C   1 
ATOM   15846 O O   . LEU D 1 371 ? -15.732  18.300  13.469  1.00 101.70 ? 431 LEU D O   1 
ATOM   15847 C CB  . LEU D 1 371 ? -14.021  17.149  10.899  1.00 116.56 ? 431 LEU D CB  1 
ATOM   15848 C CG  . LEU D 1 371 ? -13.958  16.340  9.599   1.00 118.00 ? 431 LEU D CG  1 
ATOM   15849 C CD1 . LEU D 1 371 ? -14.661  15.005  9.722   1.00 107.05 ? 431 LEU D CD1 1 
ATOM   15850 C CD2 . LEU D 1 371 ? -14.515  17.111  8.407   1.00 130.69 ? 431 LEU D CD2 1 
ATOM   15851 N N   . GLN D 1 372 ? -16.561  16.386  12.594  1.00 103.29 ? 432 GLN D N   1 
ATOM   15852 C CA  . GLN D 1 372 ? -17.026  15.755  13.864  1.00 112.66 ? 432 GLN D CA  1 
ATOM   15853 C C   . GLN D 1 372 ? -15.794  15.129  14.538  1.00 121.22 ? 432 GLN D C   1 
ATOM   15854 O O   . GLN D 1 372 ? -14.864  14.724  13.843  1.00 122.12 ? 432 GLN D O   1 
ATOM   15855 C CB  . GLN D 1 372 ? -18.185  14.790  13.550  1.00 104.69 ? 432 GLN D CB  1 
ATOM   15856 C CG  . GLN D 1 372 ? -19.496  15.474  13.139  1.00 88.26  ? 432 GLN D CG  1 
ATOM   15857 C CD  . GLN D 1 372 ? -19.767  15.675  11.655  1.00 83.21  ? 432 GLN D CD  1 
ATOM   15858 O OE1 . GLN D 1 372 ? -18.891  15.718  10.791  1.00 63.96  ? 432 GLN D OE1 1 
ATOM   15859 N NE2 . GLN D 1 372 ? -21.039  15.809  11.325  1.00 88.29  ? 432 GLN D NE2 1 
ATOM   15860 N N   . PRO D 1 373 ? -15.701  15.079  15.892  1.00 124.83 ? 433 PRO D N   1 
ATOM   15861 C CA  . PRO D 1 373 ? -14.430  14.753  16.558  1.00 116.35 ? 433 PRO D CA  1 
ATOM   15862 C C   . PRO D 1 373 ? -13.855  13.356  16.244  1.00 105.96 ? 433 PRO D C   1 
ATOM   15863 O O   . PRO D 1 373 ? -12.699  13.246  15.933  1.00 96.77  ? 433 PRO D O   1 
ATOM   15864 C CB  . PRO D 1 373 ? -14.773  14.840  18.058  1.00 113.26 ? 433 PRO D CB  1 
ATOM   15865 C CG  . PRO D 1 373 ? -16.286  14.642  18.118  1.00 111.89 ? 433 PRO D CG  1 
ATOM   15866 C CD  . PRO D 1 373 ? -16.802  15.299  16.854  1.00 119.59 ? 433 PRO D CD  1 
ATOM   15867 N N   . PHE D 1 374 ? -14.687  12.320  16.315  1.00 94.35  ? 434 PHE D N   1 
ATOM   15868 C CA  . PHE D 1 374 ? -14.305  10.885  16.245  1.00 92.35  ? 434 PHE D CA  1 
ATOM   15869 C C   . PHE D 1 374 ? -13.998  10.451  14.809  1.00 89.29  ? 434 PHE D C   1 
ATOM   15870 O O   . PHE D 1 374 ? -13.834  9.217   14.582  1.00 81.25  ? 434 PHE D O   1 
ATOM   15871 C CB  . PHE D 1 374 ? -15.443  10.006  16.768  1.00 109.29 ? 434 PHE D CB  1 
ATOM   15872 C CG  . PHE D 1 374 ? -16.720  10.017  15.954  1.00 111.24 ? 434 PHE D CG  1 
ATOM   15873 C CD1 . PHE D 1 374 ? -17.647  11.049  16.088  1.00 107.92 ? 434 PHE D CD1 1 
ATOM   15874 C CD2 . PHE D 1 374 ? -17.022  8.971   15.094  1.00 91.35  ? 434 PHE D CD2 1 
ATOM   15875 C CE1 . PHE D 1 374 ? -18.827  11.043  15.366  1.00 96.72  ? 434 PHE D CE1 1 
ATOM   15876 C CE2 . PHE D 1 374 ? -18.208  8.963   14.386  1.00 86.49  ? 434 PHE D CE2 1 
ATOM   15877 C CZ  . PHE D 1 374 ? -19.105  9.999   14.518  1.00 94.77  ? 434 PHE D CZ  1 
ATOM   15878 N N   . LYS D 1 375 ? -13.983  11.408  13.870  1.00 88.68  ? 435 LYS D N   1 
ATOM   15879 C CA  . LYS D 1 375 ? -13.705  11.196  12.423  1.00 89.34  ? 435 LYS D CA  1 
ATOM   15880 C C   . LYS D 1 375 ? -12.291  11.694  12.076  1.00 89.59  ? 435 LYS D C   1 
ATOM   15881 O O   . LYS D 1 375 ? -11.696  11.166  11.092  1.00 78.12  ? 435 LYS D O   1 
ATOM   15882 C CB  . LYS D 1 375 ? -14.752  11.913  11.555  1.00 81.47  ? 435 LYS D CB  1 
ATOM   15883 C CG  . LYS D 1 375 ? -16.196  11.449  11.717  1.00 82.19  ? 435 LYS D CG  1 
ATOM   15884 C CD  . LYS D 1 375 ? -17.084  11.642  10.488  1.00 77.75  ? 435 LYS D CD  1 
ATOM   15885 C CE  . LYS D 1 375 ? -18.572  11.575  10.770  1.00 70.55  ? 435 LYS D CE  1 
ATOM   15886 N NZ  . LYS D 1 375 ? -19.352  12.485  9.893   1.00 67.48  ? 435 LYS D NZ  1 
ATOM   15887 N N   . LYS D 1 376 ? -11.756  12.653  12.848  1.00 93.05  ? 436 LYS D N   1 
ATOM   15888 C CA  . LYS D 1 376 ? -10.451  13.330  12.581  1.00 91.31  ? 436 LYS D CA  1 
ATOM   15889 C C   . LYS D 1 376 ? -9.330   12.306  12.384  1.00 82.14  ? 436 LYS D C   1 
ATOM   15890 O O   . LYS D 1 376 ? -8.494   12.470  11.503  1.00 73.47  ? 436 LYS D O   1 
ATOM   15891 C CB  . LYS D 1 376 ? -10.137  14.330  13.701  1.00 103.86 ? 436 LYS D CB  1 
ATOM   15892 C CG  . LYS D 1 376 ? -10.768  15.711  13.535  1.00 114.69 ? 436 LYS D CG  1 
ATOM   15893 C CD  . LYS D 1 376 ? -11.255  16.365  14.819  1.00 118.92 ? 436 LYS D CD  1 
ATOM   15894 C CE  . LYS D 1 376 ? -12.152  17.545  14.546  1.00 111.30 ? 436 LYS D CE  1 
ATOM   15895 N NZ  . LYS D 1 376 ? -12.529  18.219  15.806  1.00 109.44 ? 436 LYS D NZ  1 
ATOM   15896 N N   . PRO D 1 377 ? -9.251   11.219  13.191  1.00 79.46  ? 437 PRO D N   1 
ATOM   15897 C CA  . PRO D 1 377 ? -8.227   10.190  12.986  1.00 69.49  ? 437 PRO D CA  1 
ATOM   15898 C C   . PRO D 1 377 ? -8.262   9.462   11.643  1.00 59.77  ? 437 PRO D C   1 
ATOM   15899 O O   . PRO D 1 377 ? -7.338   8.707   11.364  1.00 64.16  ? 437 PRO D O   1 
ATOM   15900 C CB  . PRO D 1 377 ? -8.496   9.145   14.082  1.00 71.76  ? 437 PRO D CB  1 
ATOM   15901 C CG  . PRO D 1 377 ? -9.240   9.921   15.155  1.00 77.16  ? 437 PRO D CG  1 
ATOM   15902 C CD  . PRO D 1 377 ? -10.053  10.964  14.404  1.00 81.14  ? 437 PRO D CD  1 
ATOM   15903 N N   . TRP D 1 378 ? -9.316   9.656   10.853  1.00 53.88  ? 438 TRP D N   1 
ATOM   15904 C CA  . TRP D 1 378 ? -9.448   8.974   9.545   1.00 57.24  ? 438 TRP D CA  1 
ATOM   15905 C C   . TRP D 1 378 ? -9.331   9.982   8.389   1.00 60.68  ? 438 TRP D C   1 
ATOM   15906 O O   . TRP D 1 378 ? -9.308   9.544   7.211   1.00 58.32  ? 438 TRP D O   1 
ATOM   15907 C CB  . TRP D 1 378 ? -10.748  8.203   9.578   1.00 54.82  ? 438 TRP D CB  1 
ATOM   15908 C CG  . TRP D 1 378 ? -10.883  7.369   10.814  1.00 55.68  ? 438 TRP D CG  1 
ATOM   15909 C CD1 . TRP D 1 378 ? -11.638  7.661   11.910  1.00 60.25  ? 438 TRP D CD1 1 
ATOM   15910 C CD2 . TRP D 1 378 ? -10.243  6.114   11.097  1.00 53.89  ? 438 TRP D CD2 1 
ATOM   15911 N NE1 . TRP D 1 378 ? -11.531  6.671   12.850  1.00 55.44  ? 438 TRP D NE1 1 
ATOM   15912 C CE2 . TRP D 1 378 ? -10.701  5.693   12.371  1.00 54.93  ? 438 TRP D CE2 1 
ATOM   15913 C CE3 . TRP D 1 378 ? -9.364   5.284   10.395  1.00 52.69  ? 438 TRP D CE3 1 
ATOM   15914 C CZ2 . TRP D 1 378 ? -10.322  4.481   12.953  1.00 52.89  ? 438 TRP D CZ2 1 
ATOM   15915 C CZ3 . TRP D 1 378 ? -8.991   4.081   10.969  1.00 54.44  ? 438 TRP D CZ3 1 
ATOM   15916 C CH2 . TRP D 1 378 ? -9.443   3.699   12.245  1.00 56.24  ? 438 TRP D CH2 1 
ATOM   15917 N N   . ALA D 1 379 ? -9.194   11.270  8.729   1.00 61.37  ? 439 ALA D N   1 
ATOM   15918 C CA  . ALA D 1 379 ? -9.029   12.414  7.799   1.00 64.20  ? 439 ALA D CA  1 
ATOM   15919 C C   . ALA D 1 379 ? -7.607   12.450  7.237   1.00 63.71  ? 439 ALA D C   1 
ATOM   15920 O O   . ALA D 1 379 ? -6.840   13.386  7.581   1.00 90.18  ? 439 ALA D O   1 
ATOM   15921 C CB  . ALA D 1 379 ? -9.365   13.711  8.513   1.00 77.90  ? 439 ALA D CB  1 
ATOM   15922 N N   . HIS D 1 380 ? -7.280   11.501  6.364   1.00 55.20  ? 440 HIS D N   1 
ATOM   15923 C CA  . HIS D 1 380 ? -5.978   11.425  5.651   1.00 60.34  ? 440 HIS D CA  1 
ATOM   15924 C C   . HIS D 1 380 ? -5.855   12.623  4.701   1.00 63.51  ? 440 HIS D C   1 
ATOM   15925 O O   . HIS D 1 380 ? -6.719   13.490  4.741   1.00 73.21  ? 440 HIS D O   1 
ATOM   15926 C CB  . HIS D 1 380 ? -5.841   10.033  4.999   1.00 60.36  ? 440 HIS D CB  1 
ATOM   15927 C CG  . HIS D 1 380 ? -6.155   8.939   5.974   1.00 63.21  ? 440 HIS D CG  1 
ATOM   15928 N ND1 . HIS D 1 380 ? -5.674   8.948   7.279   1.00 62.62  ? 440 HIS D ND1 1 
ATOM   15929 C CD2 . HIS D 1 380 ? -6.936   7.844   5.869   1.00 58.94  ? 440 HIS D CD2 1 
ATOM   15930 C CE1 . HIS D 1 380 ? -6.139   7.909   7.924   1.00 68.13  ? 440 HIS D CE1 1 
ATOM   15931 N NE2 . HIS D 1 380 ? -6.912   7.213   7.076   1.00 62.14  ? 440 HIS D NE2 1 
ATOM   15932 N N   . GLU D 1 381 ? -4.806   12.701  3.883   1.00 69.11  ? 441 GLU D N   1 
ATOM   15933 C CA  . GLU D 1 381 ? -4.632   13.764  2.846   1.00 68.68  ? 441 GLU D CA  1 
ATOM   15934 C C   . GLU D 1 381 ? -4.984   13.198  1.460   1.00 68.30  ? 441 GLU D C   1 
ATOM   15935 O O   . GLU D 1 381 ? -4.342   12.224  1.031   1.00 80.78  ? 441 GLU D O   1 
ATOM   15936 C CB  . GLU D 1 381 ? -3.217   14.350  2.896   1.00 75.74  ? 441 GLU D CB  1 
ATOM   15937 C CG  . GLU D 1 381 ? -3.154   15.749  3.522   1.00 81.12  ? 441 GLU D CG  1 
ATOM   15938 C CD  . GLU D 1 381 ? -3.697   16.875  2.643   1.00 92.56  ? 441 GLU D CD  1 
ATOM   15939 O OE1 . GLU D 1 381 ? -3.671   16.755  1.385   1.00 86.75  ? 441 GLU D OE1 1 
ATOM   15940 O OE2 . GLU D 1 381 ? -4.145   17.888  3.209   1.00 100.44 ? 441 GLU D OE2 1 
ATOM   15941 N N   . HIS D 1 382 ? -5.985   13.791  0.808   1.00 67.23  ? 442 HIS D N   1 
ATOM   15942 C CA  . HIS D 1 382 ? -6.573   13.347  -0.486  1.00 75.89  ? 442 HIS D CA  1 
ATOM   15943 C C   . HIS D 1 382 ? -7.495   14.450  -0.999  1.00 69.78  ? 442 HIS D C   1 
ATOM   15944 O O   . HIS D 1 382 ? -7.870   15.295  -0.183  1.00 65.90  ? 442 HIS D O   1 
ATOM   15945 C CB  . HIS D 1 382 ? -7.363   12.049  -0.278  1.00 80.45  ? 442 HIS D CB  1 
ATOM   15946 C CG  . HIS D 1 382 ? -7.521   11.223  -1.504  1.00 70.35  ? 442 HIS D CG  1 
ATOM   15947 N ND1 . HIS D 1 382 ? -8.538   11.428  -2.412  1.00 67.55  ? 442 HIS D ND1 1 
ATOM   15948 C CD2 . HIS D 1 382 ? -6.795   10.183  -1.960  1.00 67.71  ? 442 HIS D CD2 1 
ATOM   15949 C CE1 . HIS D 1 382 ? -8.429   10.541  -3.379  1.00 70.38  ? 442 HIS D CE1 1 
ATOM   15950 N NE2 . HIS D 1 382 ? -7.357   9.771   -3.141  1.00 61.81  ? 442 HIS D NE2 1 
ATOM   15951 N N   . GLU D 1 383 ? -7.849   14.451  -2.281  1.00 78.76  ? 443 GLU D N   1 
ATOM   15952 C CA  . GLU D 1 383 ? -8.704   15.546  -2.814  1.00 94.17  ? 443 GLU D CA  1 
ATOM   15953 C C   . GLU D 1 383 ? -10.144  15.209  -2.455  1.00 83.36  ? 443 GLU D C   1 
ATOM   15954 O O   . GLU D 1 383 ? -10.450  14.020  -2.356  1.00 73.96  ? 443 GLU D O   1 
ATOM   15955 C CB  . GLU D 1 383 ? -8.424   15.794  -4.296  1.00 118.30 ? 443 GLU D CB  1 
ATOM   15956 C CG  . GLU D 1 383 ? -7.027   16.397  -4.536  1.00 135.42 ? 443 GLU D CG  1 
ATOM   15957 C CD  . GLU D 1 383 ? -6.851   17.916  -4.441  1.00 118.05 ? 443 GLU D CD  1 
ATOM   15958 O OE1 . GLU D 1 383 ? -7.566   18.630  -5.201  1.00 91.50  ? 443 GLU D OE1 1 
ATOM   15959 O OE2 . GLU D 1 383 ? -5.951   18.390  -3.657  1.00 83.47  ? 443 GLU D OE2 1 
ATOM   15960 N N   . PRO D 1 384 ? -10.998  16.218  -2.109  1.00 78.21  ? 444 PRO D N   1 
ATOM   15961 C CA  . PRO D 1 384 ? -12.377  15.942  -1.702  1.00 72.54  ? 444 PRO D CA  1 
ATOM   15962 C C   . PRO D 1 384 ? -13.094  15.139  -2.801  1.00 72.03  ? 444 PRO D C   1 
ATOM   15963 O O   . PRO D 1 384 ? -13.038  15.554  -3.916  1.00 67.03  ? 444 PRO D O   1 
ATOM   15964 C CB  . PRO D 1 384 ? -13.011  17.325  -1.487  1.00 73.51  ? 444 PRO D CB  1 
ATOM   15965 C CG  . PRO D 1 384 ? -12.029  18.337  -2.074  1.00 74.35  ? 444 PRO D CG  1 
ATOM   15966 C CD  . PRO D 1 384 ? -10.674  17.658  -2.027  1.00 76.60  ? 444 PRO D CD  1 
ATOM   15967 N N   . LEU D 1 385 ? -13.711  14.008  -2.453  1.00 75.56  ? 445 LEU D N   1 
ATOM   15968 C CA  . LEU D 1 385 ? -14.592  13.208  -3.340  1.00 71.30  ? 445 LEU D CA  1 
ATOM   15969 C C   . LEU D 1 385 ? -16.016  13.245  -2.781  1.00 72.07  ? 445 LEU D C   1 
ATOM   15970 O O   . LEU D 1 385 ? -16.147  13.250  -1.572  1.00 80.07  ? 445 LEU D O   1 
ATOM   15971 C CB  . LEU D 1 385 ? -14.033  11.788  -3.436  1.00 65.82  ? 445 LEU D CB  1 
ATOM   15972 C CG  . LEU D 1 385 ? -13.109  11.567  -4.633  1.00 64.69  ? 445 LEU D CG  1 
ATOM   15973 C CD1 . LEU D 1 385 ? -12.117  12.691  -4.808  1.00 69.28  ? 445 LEU D CD1 1 
ATOM   15974 C CD2 . LEU D 1 385 ? -12.384  10.248  -4.505  1.00 66.04  ? 445 LEU D CD2 1 
ATOM   15975 N N   . LYS D 1 386 ? -17.031  13.265  -3.648  1.00 78.87  ? 446 LYS D N   1 
ATOM   15976 C CA  . LYS D 1 386 ? -18.444  13.524  -3.259  1.00 79.13  ? 446 LYS D CA  1 
ATOM   15977 C C   . LYS D 1 386 ? -19.128  12.192  -2.982  1.00 67.38  ? 446 LYS D C   1 
ATOM   15978 O O   . LYS D 1 386 ? -19.823  12.131  -1.983  1.00 82.64  ? 446 LYS D O   1 
ATOM   15979 C CB  . LYS D 1 386 ? -19.256  14.257  -4.330  1.00 90.09  ? 446 LYS D CB  1 
ATOM   15980 C CG  . LYS D 1 386 ? -18.484  15.243  -5.182  1.00 108.06 ? 446 LYS D CG  1 
ATOM   15981 C CD  . LYS D 1 386 ? -17.726  16.270  -4.368  1.00 123.36 ? 446 LYS D CD  1 
ATOM   15982 C CE  . LYS D 1 386 ? -18.612  17.265  -3.644  1.00 120.12 ? 446 LYS D CE  1 
ATOM   15983 N NZ  . LYS D 1 386 ? -17.834  18.435  -3.159  1.00 119.65 ? 446 LYS D NZ  1 
ATOM   15984 N N   . THR D 1 387 ? -18.932  11.169  -3.809  1.00 53.41  ? 447 THR D N   1 
ATOM   15985 C CA  . THR D 1 387 ? -19.706  9.911   -3.733  1.00 57.14  ? 447 THR D CA  1 
ATOM   15986 C C   . THR D 1 387 ? -18.784  8.739   -3.423  1.00 56.67  ? 447 THR D C   1 
ATOM   15987 O O   . THR D 1 387 ? -17.583  8.820   -3.771  1.00 54.57  ? 447 THR D O   1 
ATOM   15988 C CB  . THR D 1 387 ? -20.398  9.628   -5.063  1.00 67.96  ? 447 THR D CB  1 
ATOM   15989 O OG1 . THR D 1 387 ? -19.340  9.518   -6.024  1.00 85.77  ? 447 THR D OG1 1 
ATOM   15990 C CG2 . THR D 1 387 ? -21.395  10.689  -5.460  1.00 71.17  ? 447 THR D CG2 1 
ATOM   15991 N N   . LEU D 1 388 ? -19.361  7.678   -2.852  1.00 58.15  ? 448 LEU D N   1 
ATOM   15992 C CA  . LEU D 1 388 ? -18.687  6.373   -2.630  1.00 53.84  ? 448 LEU D CA  1 
ATOM   15993 C C   . LEU D 1 388 ? -18.100  5.904   -3.950  1.00 49.73  ? 448 LEU D C   1 
ATOM   15994 O O   . LEU D 1 388 ? -16.981  5.404   -3.926  1.00 41.06  ? 448 LEU D O   1 
ATOM   15995 C CB  . LEU D 1 388 ? -19.654  5.315   -2.084  1.00 58.46  ? 448 LEU D CB  1 
ATOM   15996 C CG  . LEU D 1 388 ? -19.101  3.888   -2.035  1.00 64.48  ? 448 LEU D CG  1 
ATOM   15997 C CD1 . LEU D 1 388 ? -17.968  3.796   -1.054  1.00 66.99  ? 448 LEU D CD1 1 
ATOM   15998 C CD2 . LEU D 1 388 ? -20.143  2.871   -1.655  1.00 72.07  ? 448 LEU D CD2 1 
ATOM   15999 N N   . TYR D 1 389 ? -18.822  6.047   -5.060  1.00 56.36  ? 449 TYR D N   1 
ATOM   16000 C CA  . TYR D 1 389 ? -18.305  5.588   -6.383  1.00 64.20  ? 449 TYR D CA  1 
ATOM   16001 C C   . TYR D 1 389 ? -16.962  6.274   -6.679  1.00 61.17  ? 449 TYR D C   1 
ATOM   16002 O O   . TYR D 1 389 ? -16.072  5.623   -7.173  1.00 57.64  ? 449 TYR D O   1 
ATOM   16003 C CB  . TYR D 1 389 ? -19.321  5.808   -7.510  1.00 62.55  ? 449 TYR D CB  1 
ATOM   16004 C CG  . TYR D 1 389 ? -18.788  5.464   -8.875  1.00 60.42  ? 449 TYR D CG  1 
ATOM   16005 C CD1 . TYR D 1 389 ? -18.666  4.136   -9.279  1.00 65.04  ? 449 TYR D CD1 1 
ATOM   16006 C CD2 . TYR D 1 389 ? -18.324  6.463   -9.722  1.00 58.11  ? 449 TYR D CD2 1 
ATOM   16007 C CE1 . TYR D 1 389 ? -18.125  3.811   -10.514 1.00 65.33  ? 449 TYR D CE1 1 
ATOM   16008 C CE2 . TYR D 1 389 ? -17.760  6.151   -10.950 1.00 61.37  ? 449 TYR D CE2 1 
ATOM   16009 C CZ  . TYR D 1 389 ? -17.668  4.822   -11.353 1.00 67.50  ? 449 TYR D CZ  1 
ATOM   16010 O OH  . TYR D 1 389 ? -17.108  4.484   -12.557 1.00 59.79  ? 449 TYR D OH  1 
ATOM   16011 N N   . ASP D 1 390 ? -16.827  7.567   -6.394  1.00 65.85  ? 450 ASP D N   1 
ATOM   16012 C CA  . ASP D 1 390 ? -15.592  8.338   -6.696  1.00 58.62  ? 450 ASP D CA  1 
ATOM   16013 C C   . ASP D 1 390 ? -14.455  7.816   -5.833  1.00 53.86  ? 450 ASP D C   1 
ATOM   16014 O O   . ASP D 1 390 ? -13.360  7.545   -6.377  1.00 59.25  ? 450 ASP D O   1 
ATOM   16015 C CB  . ASP D 1 390 ? -15.790  9.824   -6.444  1.00 54.52  ? 450 ASP D CB  1 
ATOM   16016 C CG  . ASP D 1 390 ? -16.639  10.464  -7.507  1.00 58.94  ? 450 ASP D CG  1 
ATOM   16017 O OD1 . ASP D 1 390 ? -16.993  9.765   -8.489  1.00 54.96  ? 450 ASP D OD1 1 
ATOM   16018 O OD2 . ASP D 1 390 ? -16.963  11.644  -7.317  1.00 80.99  ? 450 ASP D OD2 1 
ATOM   16019 N N   . ALA D 1 391 ? -14.714  7.676   -4.537  1.00 49.89  ? 451 ALA D N   1 
ATOM   16020 C CA  . ALA D 1 391 ? -13.746  7.063   -3.604  1.00 52.35  ? 451 ALA D CA  1 
ATOM   16021 C C   . ALA D 1 391 ? -13.378  5.650   -4.104  1.00 54.31  ? 451 ALA D C   1 
ATOM   16022 O O   . ALA D 1 391 ? -12.193  5.386   -4.225  1.00 51.81  ? 451 ALA D O   1 
ATOM   16023 C CB  . ALA D 1 391 ? -14.291  7.084   -2.200  1.00 49.47  ? 451 ALA D CB  1 
ATOM   16024 N N   . VAL D 1 392 ? -14.344  4.788   -4.447  1.00 55.33  ? 452 VAL D N   1 
ATOM   16025 C CA  . VAL D 1 392 ? -14.050  3.364   -4.777  1.00 51.20  ? 452 VAL D CA  1 
ATOM   16026 C C   . VAL D 1 392 ? -13.022  3.377   -5.899  1.00 57.55  ? 452 VAL D C   1 
ATOM   16027 O O   . VAL D 1 392 ? -12.058  2.554   -5.878  1.00 80.84  ? 452 VAL D O   1 
ATOM   16028 C CB  . VAL D 1 392 ? -15.295  2.538   -5.153  1.00 47.71  ? 452 VAL D CB  1 
ATOM   16029 C CG1 . VAL D 1 392 ? -14.943  1.242   -5.872  1.00 48.21  ? 452 VAL D CG1 1 
ATOM   16030 C CG2 . VAL D 1 392 ? -16.131  2.216   -3.935  1.00 49.45  ? 452 VAL D CG2 1 
ATOM   16031 N N   . GLN D 1 393 ? -13.190  4.310   -6.832  1.00 61.72  ? 453 GLN D N   1 
ATOM   16032 C CA  . GLN D 1 393 ? -12.415  4.305   -8.096  1.00 62.94  ? 453 GLN D CA  1 
ATOM   16033 C C   . GLN D 1 393 ? -11.038  4.903   -7.832  1.00 56.90  ? 453 GLN D C   1 
ATOM   16034 O O   . GLN D 1 393 ? -10.086  4.340   -8.397  1.00 61.67  ? 453 GLN D O   1 
ATOM   16035 C CB  . GLN D 1 393 ? -13.206  5.008   -9.196  1.00 58.40  ? 453 GLN D CB  1 
ATOM   16036 C CG  . GLN D 1 393 ? -13.103  4.318   -10.539 1.00 66.45  ? 453 GLN D CG  1 
ATOM   16037 C CD  . GLN D 1 393 ? -13.827  3.004   -10.686 1.00 57.85  ? 453 GLN D CD  1 
ATOM   16038 O OE1 . GLN D 1 393 ? -13.480  1.998   -10.072 1.00 53.13  ? 453 GLN D OE1 1 
ATOM   16039 N NE2 . GLN D 1 393 ? -14.738  2.986   -11.634 1.00 60.12  ? 453 GLN D NE2 1 
ATOM   16040 N N   . SER D 1 394 ? -10.938  5.931   -6.975  1.00 49.48  ? 454 SER D N   1 
ATOM   16041 C CA  . SER D 1 394 ? -9.667   6.631   -6.663  1.00 54.06  ? 454 SER D CA  1 
ATOM   16042 C C   . SER D 1 394 ? -8.815   5.782   -5.702  1.00 53.67  ? 454 SER D C   1 
ATOM   16043 O O   . SER D 1 394 ? -7.649   5.471   -6.044  1.00 48.32  ? 454 SER D O   1 
ATOM   16044 C CB  . SER D 1 394 ? -9.919   8.020   -6.135  1.00 57.76  ? 454 SER D CB  1 
ATOM   16045 O OG  . SER D 1 394 ? -8.693   8.717   -5.943  1.00 61.74  ? 454 SER D OG  1 
ATOM   16046 N N   . ILE D 1 395 ? -9.381   5.379   -4.565  1.00 53.08  ? 455 ILE D N   1 
ATOM   16047 C CA  . ILE D 1 395 ? -8.673   4.658   -3.457  1.00 52.99  ? 455 ILE D CA  1 
ATOM   16048 C C   . ILE D 1 395 ? -8.333   3.239   -3.907  1.00 49.84  ? 455 ILE D C   1 
ATOM   16049 O O   . ILE D 1 395 ? -7.343   2.709   -3.384  1.00 45.27  ? 455 ILE D O   1 
ATOM   16050 C CB  . ILE D 1 395 ? -9.503   4.641   -2.154  1.00 51.89  ? 455 ILE D CB  1 
ATOM   16051 C CG1 . ILE D 1 395 ? -9.392   5.971   -1.400  1.00 58.08  ? 455 ILE D CG1 1 
ATOM   16052 C CG2 . ILE D 1 395 ? -9.089   3.495   -1.249  1.00 49.11  ? 455 ILE D CG2 1 
ATOM   16053 C CD1 . ILE D 1 395 ? -9.703   7.217   -2.173  1.00 62.23  ? 455 ILE D CD1 1 
ATOM   16054 N N   . LYS D 1 396 ? -9.146   2.643   -4.787  1.00 42.31  ? 456 LYS D N   1 
ATOM   16055 C CA  . LYS D 1 396 ? -8.914   1.261   -5.262  1.00 48.59  ? 456 LYS D CA  1 
ATOM   16056 C C   . LYS D 1 396 ? -8.777   0.316   -4.078  1.00 45.21  ? 456 LYS D C   1 
ATOM   16057 O O   . LYS D 1 396 ? -7.844   -0.461  -3.991  1.00 37.19  ? 456 LYS D O   1 
ATOM   16058 C CB  . LYS D 1 396 ? -7.685   1.188   -6.151  1.00 58.27  ? 456 LYS D CB  1 
ATOM   16059 C CG  . LYS D 1 396 ? -7.831   2.024   -7.416  1.00 67.50  ? 456 LYS D CG  1 
ATOM   16060 C CD  . LYS D 1 396 ? -7.384   1.348   -8.702  1.00 67.45  ? 456 LYS D CD  1 
ATOM   16061 C CE  . LYS D 1 396 ? -6.776   2.314   -9.702  1.00 73.21  ? 456 LYS D CE  1 
ATOM   16062 N NZ  . LYS D 1 396 ? -6.266   1.595   -10.889 1.00 78.19  ? 456 LYS D NZ  1 
ATOM   16063 N N   . PRO D 1 397 ? -9.782   0.290   -3.180  1.00 54.05  ? 457 PRO D N   1 
ATOM   16064 C CA  . PRO D 1 397 ? -9.730   -0.570  -1.995  1.00 52.93  ? 457 PRO D CA  1 
ATOM   16065 C C   . PRO D 1 397 ? -9.817   -2.083  -2.270  1.00 49.82  ? 457 PRO D C   1 
ATOM   16066 O O   . PRO D 1 397 ? -10.284  -2.500  -3.302  1.00 43.16  ? 457 PRO D O   1 
ATOM   16067 C CB  . PRO D 1 397 ? -10.985  -0.122  -1.232  1.00 59.47  ? 457 PRO D CB  1 
ATOM   16068 C CG  . PRO D 1 397 ? -11.977  0.282   -2.335  1.00 54.77  ? 457 PRO D CG  1 
ATOM   16069 C CD  . PRO D 1 397 ? -11.081  0.982   -3.332  1.00 52.70  ? 457 PRO D CD  1 
ATOM   16070 N N   . THR D 1 398 ? -9.334   -2.881  -1.325  1.00 56.34  ? 458 THR D N   1 
ATOM   16071 C CA  . THR D 1 398 ? -9.388   -4.369  -1.358  1.00 58.83  ? 458 THR D CA  1 
ATOM   16072 C C   . THR D 1 398 ? -10.586  -4.857  -0.547  1.00 60.55  ? 458 THR D C   1 
ATOM   16073 O O   . THR D 1 398 ? -11.012  -6.023  -0.776  1.00 57.87  ? 458 THR D O   1 
ATOM   16074 C CB  . THR D 1 398 ? -8.081   -5.027  -0.896  1.00 58.81  ? 458 THR D CB  1 
ATOM   16075 O OG1 . THR D 1 398 ? -7.794   -4.749  0.482   1.00 54.51  ? 458 THR D OG1 1 
ATOM   16076 C CG2 . THR D 1 398 ? -6.917   -4.581  -1.756  1.00 64.22  ? 458 THR D CG2 1 
ATOM   16077 N N   . VAL D 1 399 ? -11.083  -4.001  0.354   1.00 58.52  ? 459 VAL D N   1 
ATOM   16078 C CA  . VAL D 1 399 ? -12.206  -4.311  1.284   1.00 61.81  ? 459 VAL D CA  1 
ATOM   16079 C C   . VAL D 1 399 ? -13.171  -3.120  1.312   1.00 57.81  ? 459 VAL D C   1 
ATOM   16080 O O   . VAL D 1 399 ? -12.737  -1.989  1.687   1.00 44.82  ? 459 VAL D O   1 
ATOM   16081 C CB  . VAL D 1 399 ? -11.700  -4.621  2.699   1.00 60.52  ? 459 VAL D CB  1 
ATOM   16082 C CG1 . VAL D 1 399 ? -12.857  -4.913  3.631   1.00 60.44  ? 459 VAL D CG1 1 
ATOM   16083 C CG2 . VAL D 1 399 ? -10.712  -5.768  2.710   1.00 61.91  ? 459 VAL D CG2 1 
ATOM   16084 N N   . LEU D 1 400 ? -14.429  -3.399  0.950   1.00 51.67  ? 460 LEU D N   1 
ATOM   16085 C CA  . LEU D 1 400 ? -15.550  -2.434  0.957   1.00 50.22  ? 460 LEU D CA  1 
ATOM   16086 C C   . LEU D 1 400 ? -16.568  -2.866  2.006   1.00 52.84  ? 460 LEU D C   1 
ATOM   16087 O O   . LEU D 1 400 ? -17.212  -3.913  1.804   1.00 64.75  ? 460 LEU D O   1 
ATOM   16088 C CB  . LEU D 1 400 ? -16.189  -2.412  -0.427  1.00 48.95  ? 460 LEU D CB  1 
ATOM   16089 C CG  . LEU D 1 400 ? -17.346  -1.433  -0.591  1.00 49.80  ? 460 LEU D CG  1 
ATOM   16090 C CD1 . LEU D 1 400 ? -16.899  0.019   -0.457  1.00 49.78  ? 460 LEU D CD1 1 
ATOM   16091 C CD2 . LEU D 1 400 ? -18.023  -1.656  -1.929  1.00 53.05  ? 460 LEU D CD2 1 
ATOM   16092 N N   . ILE D 1 401 ? -16.693  -2.071  3.072   1.00 55.75  ? 461 ILE D N   1 
ATOM   16093 C CA  . ILE D 1 401 ? -17.607  -2.326  4.224   1.00 54.77  ? 461 ILE D CA  1 
ATOM   16094 C C   . ILE D 1 401 ? -18.670  -1.226  4.266   1.00 56.22  ? 461 ILE D C   1 
ATOM   16095 O O   . ILE D 1 401 ? -18.304  -0.027  4.237   1.00 55.63  ? 461 ILE D O   1 
ATOM   16096 C CB  . ILE D 1 401 ? -16.796  -2.395  5.525   1.00 52.47  ? 461 ILE D CB  1 
ATOM   16097 C CG1 . ILE D 1 401 ? -15.929  -3.654  5.593   1.00 58.01  ? 461 ILE D CG1 1 
ATOM   16098 C CG2 . ILE D 1 401 ? -17.706  -2.309  6.724   1.00 52.22  ? 461 ILE D CG2 1 
ATOM   16099 C CD1 . ILE D 1 401 ? -14.845  -3.567  6.654   1.00 59.91  ? 461 ILE D CD1 1 
ATOM   16100 N N   . GLY D 1 402 ? -19.936  -1.635  4.315   1.00 58.32  ? 462 GLY D N   1 
ATOM   16101 C CA  . GLY D 1 402 ? -21.088  -0.721  4.345   1.00 56.18  ? 462 GLY D CA  1 
ATOM   16102 C C   . GLY D 1 402 ? -21.765  -0.731  5.701   1.00 55.62  ? 462 GLY D C   1 
ATOM   16103 O O   . GLY D 1 402 ? -22.305  -1.782  6.106   1.00 44.79  ? 462 GLY D O   1 
ATOM   16104 N N   . THR D 1 403 ? -21.774  0.418   6.362   1.00 63.62  ? 463 THR D N   1 
ATOM   16105 C CA  . THR D 1 403 ? -22.491  0.656   7.638   1.00 67.91  ? 463 THR D CA  1 
ATOM   16106 C C   . THR D 1 403 ? -23.320  1.938   7.493   1.00 58.60  ? 463 THR D C   1 
ATOM   16107 O O   . THR D 1 403 ? -23.298  2.739   8.407   1.00 62.71  ? 463 THR D O   1 
ATOM   16108 C CB  . THR D 1 403 ? -21.468  0.733   8.782   1.00 76.84  ? 463 THR D CB  1 
ATOM   16109 O OG1 . THR D 1 403 ? -20.463  1.703   8.460   1.00 83.21  ? 463 THR D OG1 1 
ATOM   16110 C CG2 . THR D 1 403 ? -20.817  -0.603  9.059   1.00 78.51  ? 463 THR D CG2 1 
ATOM   16111 N N   . SER D 1 404 ? -24.014  2.128   6.372   1.00 55.65  ? 464 SER D N   1 
ATOM   16112 C CA  . SER D 1 404 ? -24.647  3.417   5.978   1.00 59.42  ? 464 SER D CA  1 
ATOM   16113 C C   . SER D 1 404 ? -26.038  3.549   6.579   1.00 58.69  ? 464 SER D C   1 
ATOM   16114 O O   . SER D 1 404 ? -26.481  4.703   6.768   1.00 69.90  ? 464 SER D O   1 
ATOM   16115 C CB  . SER D 1 404 ? -24.736  3.561   4.485   1.00 64.67  ? 464 SER D CB  1 
ATOM   16116 O OG  . SER D 1 404 ? -24.988  2.304   3.857   1.00 64.56  ? 464 SER D OG  1 
ATOM   16117 N N   . GLY D 1 405 ? -26.699  2.405   6.792   1.00 61.29  ? 465 GLY D N   1 
ATOM   16118 C CA  . GLY D 1 405 ? -28.137  2.300   7.102   1.00 56.82  ? 465 GLY D CA  1 
ATOM   16119 C C   . GLY D 1 405 ? -29.015  2.573   5.882   1.00 59.37  ? 465 GLY D C   1 
ATOM   16120 O O   . GLY D 1 405 ? -30.223  2.774   6.059   1.00 65.86  ? 465 GLY D O   1 
ATOM   16121 N N   . VAL D 1 406 ? -28.437  2.567   4.678   1.00 61.46  ? 466 VAL D N   1 
ATOM   16122 C CA  . VAL D 1 406 ? -29.117  2.928   3.399   1.00 63.18  ? 466 VAL D CA  1 
ATOM   16123 C C   . VAL D 1 406 ? -28.994  1.744   2.443   1.00 61.07  ? 466 VAL D C   1 
ATOM   16124 O O   . VAL D 1 406 ? -27.859  1.283   2.183   1.00 63.95  ? 466 VAL D O   1 
ATOM   16125 C CB  . VAL D 1 406 ? -28.547  4.208   2.749   1.00 60.34  ? 466 VAL D CB  1 
ATOM   16126 C CG1 . VAL D 1 406 ? -29.384  4.622   1.545   1.00 55.51  ? 466 VAL D CG1 1 
ATOM   16127 C CG2 . VAL D 1 406 ? -28.411  5.347   3.752   1.00 55.57  ? 466 VAL D CG2 1 
ATOM   16128 N N   . GLY D 1 407 ? -30.129  1.280   1.933   1.00 59.64  ? 467 GLY D N   1 
ATOM   16129 C CA  . GLY D 1 407 ? -30.165  0.091   1.077   1.00 63.15  ? 467 GLY D CA  1 
ATOM   16130 C C   . GLY D 1 407 ? -29.668  0.424   -0.310  1.00 64.82  ? 467 GLY D C   1 
ATOM   16131 O O   . GLY D 1 407 ? -29.790  1.599   -0.721  1.00 63.41  ? 467 GLY D O   1 
ATOM   16132 N N   . ARG D 1 408 ? -29.094  -0.580  -0.973  1.00 69.20  ? 468 ARG D N   1 
ATOM   16133 C CA  . ARG D 1 408 ? -28.823  -0.599  -2.431  1.00 75.53  ? 468 ARG D CA  1 
ATOM   16134 C C   . ARG D 1 408 ? -27.917  0.609   -2.786  1.00 74.27  ? 468 ARG D C   1 
ATOM   16135 O O   . ARG D 1 408 ? -28.097  1.205   -3.869  1.00 64.65  ? 468 ARG D O   1 
ATOM   16136 C CB  . ARG D 1 408 ? -30.188  -0.741  -3.124  1.00 71.67  ? 468 ARG D CB  1 
ATOM   16137 C CG  . ARG D 1 408 ? -31.108  -1.826  -2.540  1.00 76.79  ? 468 ARG D CG  1 
ATOM   16138 C CD  . ARG D 1 408 ? -31.316  -3.215  -3.194  1.00 85.47  ? 468 ARG D CD  1 
ATOM   16139 N NE  . ARG D 1 408 ? -32.544  -3.342  -4.023  1.00 90.47  ? 468 ARG D NE  1 
ATOM   16140 C CZ  . ARG D 1 408 ? -33.177  -4.472  -4.411  1.00 81.23  ? 468 ARG D CZ  1 
ATOM   16141 N NH1 . ARG D 1 408 ? -34.275  -4.375  -5.130  1.00 79.32  ? 468 ARG D NH1 1 
ATOM   16142 N NH2 . ARG D 1 408 ? -32.795  -5.683  -4.054  1.00 81.22  ? 468 ARG D NH2 1 
ATOM   16143 N N   . THR D 1 409 ? -26.944  0.945   -1.919  1.00 68.88  ? 469 THR D N   1 
ATOM   16144 C CA  . THR D 1 409 ? -25.901  1.995   -2.141  1.00 60.85  ? 469 THR D CA  1 
ATOM   16145 C C   . THR D 1 409 ? -24.604  1.353   -2.676  1.00 60.67  ? 469 THR D C   1 
ATOM   16146 O O   . THR D 1 409 ? -23.722  2.105   -3.211  1.00 54.73  ? 469 THR D O   1 
ATOM   16147 C CB  . THR D 1 409 ? -25.590  2.765   -0.851  1.00 58.73  ? 469 THR D CB  1 
ATOM   16148 O OG1 . THR D 1 409 ? -25.405  1.794   0.189   1.00 63.95  ? 469 THR D OG1 1 
ATOM   16149 C CG2 . THR D 1 409 ? -26.672  3.760   -0.493  1.00 56.28  ? 469 THR D CG2 1 
ATOM   16150 N N   . PHE D 1 410 ? -24.469  0.026   -2.518  1.00 54.42  ? 470 PHE D N   1 
ATOM   16151 C CA  . PHE D 1 410 ? -23.488  -0.826  -3.235  1.00 47.84  ? 470 PHE D CA  1 
ATOM   16152 C C   . PHE D 1 410 ? -24.116  -1.226  -4.561  1.00 49.52  ? 470 PHE D C   1 
ATOM   16153 O O   . PHE D 1 410 ? -24.759  -2.279  -4.617  1.00 52.01  ? 470 PHE D O   1 
ATOM   16154 C CB  . PHE D 1 410 ? -23.052  -2.032  -2.405  1.00 48.85  ? 470 PHE D CB  1 
ATOM   16155 C CG  . PHE D 1 410 ? -22.154  -1.707  -1.238  1.00 45.68  ? 470 PHE D CG  1 
ATOM   16156 C CD1 . PHE D 1 410 ? -21.931  -0.388  -0.855  1.00 44.33  ? 470 PHE D CD1 1 
ATOM   16157 C CD2 . PHE D 1 410 ? -21.573  -2.728  -0.504  1.00 43.00  ? 470 PHE D CD2 1 
ATOM   16158 C CE1 . PHE D 1 410 ? -21.125  -0.092  0.228   1.00 47.53  ? 470 PHE D CE1 1 
ATOM   16159 C CE2 . PHE D 1 410 ? -20.780  -2.436  0.590   1.00 46.61  ? 470 PHE D CE2 1 
ATOM   16160 C CZ  . PHE D 1 410 ? -20.558  -1.125  0.955   1.00 53.05  ? 470 PHE D CZ  1 
ATOM   16161 N N   . THR D 1 411 ? -23.896  -0.364  -5.564  1.00 53.97  ? 471 THR D N   1 
ATOM   16162 C CA  . THR D 1 411 ? -24.514  -0.336  -6.911  1.00 50.97  ? 471 THR D CA  1 
ATOM   16163 C C   . THR D 1 411 ? -23.756  -1.313  -7.812  1.00 53.46  ? 471 THR D C   1 
ATOM   16164 O O   . THR D 1 411 ? -22.681  -1.776  -7.406  1.00 56.64  ? 471 THR D O   1 
ATOM   16165 C CB  . THR D 1 411 ? -24.530  1.120   -7.404  1.00 48.08  ? 471 THR D CB  1 
ATOM   16166 O OG1 . THR D 1 411 ? -23.196  1.615   -7.456  1.00 50.24  ? 471 THR D OG1 1 
ATOM   16167 C CG2 . THR D 1 411 ? -25.299  2.053   -6.502  1.00 43.72  ? 471 THR D CG2 1 
ATOM   16168 N N   . LYS D 1 412 ? -24.302  -1.622  -8.989  1.00 64.49  ? 472 LYS D N   1 
ATOM   16169 C CA  . LYS D 1 412 ? -23.657  -2.473  -10.034 1.00 68.71  ? 472 LYS D CA  1 
ATOM   16170 C C   . LYS D 1 412 ? -22.290  -1.843  -10.395 1.00 62.38  ? 472 LYS D C   1 
ATOM   16171 O O   . LYS D 1 412 ? -21.290  -2.590  -10.396 1.00 57.24  ? 472 LYS D O   1 
ATOM   16172 C CB  . LYS D 1 412 ? -24.667  -2.644  -11.184 1.00 74.31  ? 472 LYS D CB  1 
ATOM   16173 C CG  . LYS D 1 412 ? -24.380  -3.725  -12.223 1.00 77.34  ? 472 LYS D CG  1 
ATOM   16174 C CD  . LYS D 1 412 ? -25.304  -3.742  -13.445 1.00 86.12  ? 472 LYS D CD  1 
ATOM   16175 C CE  . LYS D 1 412 ? -25.337  -5.100  -14.134 1.00 102.82 ? 472 LYS D CE  1 
ATOM   16176 N NZ  . LYS D 1 412 ? -25.803  -5.046  -15.543 1.00 100.65 ? 472 LYS D NZ  1 
ATOM   16177 N N   . GLU D 1 413 ? -22.254  -0.517  -10.615 1.00 60.81  ? 473 GLU D N   1 
ATOM   16178 C CA  . GLU D 1 413 ? -21.048  0.294   -10.929 1.00 63.89  ? 473 GLU D CA  1 
ATOM   16179 C C   . GLU D 1 413 ? -19.945  0.067   -9.894  1.00 65.69  ? 473 GLU D C   1 
ATOM   16180 O O   . GLU D 1 413 ? -18.749  -0.050  -10.274 1.00 67.94  ? 473 GLU D O   1 
ATOM   16181 C CB  . GLU D 1 413 ? -21.347  1.789   -10.851 1.00 72.07  ? 473 GLU D CB  1 
ATOM   16182 C CG  . GLU D 1 413 ? -22.396  2.273   -11.818 1.00 85.67  ? 473 GLU D CG  1 
ATOM   16183 C CD  . GLU D 1 413 ? -21.935  3.587   -12.412 1.00 106.32 ? 473 GLU D CD  1 
ATOM   16184 O OE1 . GLU D 1 413 ? -21.765  3.626   -13.658 1.00 114.06 ? 473 GLU D OE1 1 
ATOM   16185 O OE2 . GLU D 1 413 ? -21.680  4.545   -11.616 1.00 98.86  ? 473 GLU D OE2 1 
ATOM   16186 N N   . ILE D 1 414 ? -20.342  0.072   -8.624  1.00 63.39  ? 474 ILE D N   1 
ATOM   16187 C CA  . ILE D 1 414 ? -19.433  -0.011  -7.448  1.00 56.49  ? 474 ILE D CA  1 
ATOM   16188 C C   . ILE D 1 414 ? -18.921  -1.443  -7.313  1.00 52.23  ? 474 ILE D C   1 
ATOM   16189 O O   . ILE D 1 414 ? -17.714  -1.584  -7.291  1.00 66.02  ? 474 ILE D O   1 
ATOM   16190 C CB  . ILE D 1 414 ? -20.150  0.515   -6.200  1.00 56.66  ? 474 ILE D CB  1 
ATOM   16191 C CG1 . ILE D 1 414 ? -20.278  2.041   -6.294  1.00 61.88  ? 474 ILE D CG1 1 
ATOM   16192 C CG2 . ILE D 1 414 ? -19.436  0.062   -4.951  1.00 60.95  ? 474 ILE D CG2 1 
ATOM   16193 C CD1 . ILE D 1 414 ? -20.544  2.741   -4.986  1.00 63.68  ? 474 ILE D CD1 1 
ATOM   16194 N N   . ILE D 1 415 ? -19.780  -2.456  -7.286  1.00 45.61  ? 475 ILE D N   1 
ATOM   16195 C CA  . ILE D 1 415 ? -19.340  -3.881  -7.225  1.00 49.87  ? 475 ILE D CA  1 
ATOM   16196 C C   . ILE D 1 415 ? -18.548  -4.246  -8.481  1.00 50.92  ? 475 ILE D C   1 
ATOM   16197 O O   . ILE D 1 415 ? -17.626  -5.059  -8.360  1.00 58.04  ? 475 ILE D O   1 
ATOM   16198 C CB  . ILE D 1 415 ? -20.518  -4.845  -7.028  1.00 53.34  ? 475 ILE D CB  1 
ATOM   16199 C CG1 . ILE D 1 415 ? -21.168  -4.551  -5.672  1.00 56.40  ? 475 ILE D CG1 1 
ATOM   16200 C CG2 . ILE D 1 415 ? -20.068  -6.304  -7.211  1.00 45.69  ? 475 ILE D CG2 1 
ATOM   16201 C CD1 . ILE D 1 415 ? -22.061  -5.632  -5.158  1.00 69.20  ? 475 ILE D CD1 1 
ATOM   16202 N N   . GLU D 1 416 ? -18.921  -3.718  -9.645  1.00 52.95  ? 476 GLU D N   1 
ATOM   16203 C CA  . GLU D 1 416 ? -18.186  -3.996  -10.910 1.00 55.77  ? 476 GLU D CA  1 
ATOM   16204 C C   . GLU D 1 416 ? -16.795  -3.357  -10.826 1.00 55.69  ? 476 GLU D C   1 
ATOM   16205 O O   . GLU D 1 416 ? -15.803  -4.075  -11.108 1.00 56.31  ? 476 GLU D O   1 
ATOM   16206 C CB  . GLU D 1 416 ? -18.969  -3.529  -12.134 1.00 55.08  ? 476 GLU D CB  1 
ATOM   16207 C CG  . GLU D 1 416 ? -20.005  -4.535  -12.601 1.00 60.70  ? 476 GLU D CG  1 
ATOM   16208 C CD  . GLU D 1 416 ? -20.514  -4.270  -14.007 1.00 71.55  ? 476 GLU D CD  1 
ATOM   16209 O OE1 . GLU D 1 416 ? -20.423  -3.107  -14.471 1.00 82.25  ? 476 GLU D OE1 1 
ATOM   16210 O OE2 . GLU D 1 416 ? -20.972  -5.235  -14.659 1.00 77.40  ? 476 GLU D OE2 1 
ATOM   16211 N N   . ALA D 1 417 ? -16.725  -2.080  -10.425 1.00 56.35  ? 477 ALA D N   1 
ATOM   16212 C CA  . ALA D 1 417 ? -15.461  -1.348  -10.172 1.00 54.39  ? 477 ALA D CA  1 
ATOM   16213 C C   . ALA D 1 417 ? -14.566  -2.175  -9.244  1.00 52.14  ? 477 ALA D C   1 
ATOM   16214 O O   . ALA D 1 417 ? -13.429  -2.398  -9.594  1.00 50.28  ? 477 ALA D O   1 
ATOM   16215 C CB  . ALA D 1 417 ? -15.750  0.010   -9.582  1.00 53.62  ? 477 ALA D CB  1 
ATOM   16216 N N   . MET D 1 418 ? -15.097  -2.620  -8.105  1.00 60.14  ? 478 MET D N   1 
ATOM   16217 C CA  . MET D 1 418 ? -14.386  -3.451  -7.088  1.00 67.15  ? 478 MET D CA  1 
ATOM   16218 C C   . MET D 1 418 ? -13.928  -4.791  -7.674  1.00 64.00  ? 478 MET D C   1 
ATOM   16219 O O   . MET D 1 418 ? -12.896  -5.278  -7.223  1.00 72.42  ? 478 MET D O   1 
ATOM   16220 C CB  . MET D 1 418 ? -15.274  -3.745  -5.875  1.00 62.86  ? 478 MET D CB  1 
ATOM   16221 C CG  . MET D 1 418 ? -15.562  -2.514  -5.024  1.00 57.26  ? 478 MET D CG  1 
ATOM   16222 S SD  . MET D 1 418 ? -14.278  -2.096  -3.856  1.00 69.31  ? 478 MET D SD  1 
ATOM   16223 C CE  . MET D 1 418 ? -13.736  -3.719  -3.307  1.00 69.41  ? 478 MET D CE  1 
ATOM   16224 N N   . SER D 1 419 ? -14.683  -5.382  -8.598  1.00 57.62  ? 479 SER D N   1 
ATOM   16225 C CA  . SER D 1 419 ? -14.381  -6.706  -9.212  1.00 57.77  ? 479 SER D CA  1 
ATOM   16226 C C   . SER D 1 419 ? -13.290  -6.534  -10.277 1.00 53.32  ? 479 SER D C   1 
ATOM   16227 O O   . SER D 1 419 ? -12.644  -7.543  -10.643 1.00 50.17  ? 479 SER D O   1 
ATOM   16228 C CB  . SER D 1 419 ? -15.638  -7.343  -9.791  1.00 56.18  ? 479 SER D CB  1 
ATOM   16229 O OG  . SER D 1 419 ? -16.706  -7.342  -8.852  1.00 65.57  ? 479 SER D OG  1 
ATOM   16230 N N   . SER D 1 420 ? -13.107  -5.298  -10.753 1.00 52.06  ? 480 SER D N   1 
ATOM   16231 C CA  . SER D 1 420 ? -12.211  -4.927  -11.879 1.00 51.33  ? 480 SER D CA  1 
ATOM   16232 C C   . SER D 1 420 ? -10.752  -4.841  -11.398 1.00 57.61  ? 480 SER D C   1 
ATOM   16233 O O   . SER D 1 420 ? -9.886   -5.347  -12.142 1.00 67.12  ? 480 SER D O   1 
ATOM   16234 C CB  . SER D 1 420 ? -12.678  -3.644  -12.572 1.00 50.56  ? 480 SER D CB  1 
ATOM   16235 O OG  . SER D 1 420 ? -12.021  -2.467  -12.081 1.00 58.07  ? 480 SER D OG  1 
ATOM   16236 N N   . PHE D 1 421 ? -10.456  -4.244  -10.223 1.00 56.12  ? 481 PHE D N   1 
ATOM   16237 C CA  . PHE D 1 421 ? -9.051   -4.057  -9.760  1.00 55.76  ? 481 PHE D CA  1 
ATOM   16238 C C   . PHE D 1 421 ? -8.658   -5.120  -8.734  1.00 49.71  ? 481 PHE D C   1 
ATOM   16239 O O   . PHE D 1 421 ? -7.507   -5.451  -8.716  1.00 69.96  ? 481 PHE D O   1 
ATOM   16240 C CB  . PHE D 1 421 ? -8.723   -2.621  -9.343  1.00 59.67  ? 481 PHE D CB  1 
ATOM   16241 C CG  . PHE D 1 421 ? -9.752   -1.893  -8.532  1.00 61.72  ? 481 PHE D CG  1 
ATOM   16242 C CD1 . PHE D 1 421 ? -9.948   -2.223  -7.200  1.00 69.86  ? 481 PHE D CD1 1 
ATOM   16243 C CD2 . PHE D 1 421 ? -10.439  -0.817  -9.064  1.00 62.69  ? 481 PHE D CD2 1 
ATOM   16244 C CE1 . PHE D 1 421 ? -10.899  -1.555  -6.443  1.00 74.95  ? 481 PHE D CE1 1 
ATOM   16245 C CE2 . PHE D 1 421 ? -11.371  -0.128  -8.298  1.00 67.51  ? 481 PHE D CE2 1 
ATOM   16246 C CZ  . PHE D 1 421 ? -11.607  -0.502  -6.994  1.00 74.46  ? 481 PHE D CZ  1 
ATOM   16247 N N   . ASN D 1 422 ? -9.567   -5.634  -7.929  1.00 56.50  ? 482 ASN D N   1 
ATOM   16248 C CA  . ASN D 1 422 ? -9.345   -6.843  -7.094  1.00 55.67  ? 482 ASN D CA  1 
ATOM   16249 C C   . ASN D 1 422 ? -9.757   -8.073  -7.900  1.00 54.63  ? 482 ASN D C   1 
ATOM   16250 O O   . ASN D 1 422 ? -10.722  -7.993  -8.666  1.00 53.47  ? 482 ASN D O   1 
ATOM   16251 C CB  . ASN D 1 422 ? -10.134  -6.776  -5.790  1.00 59.93  ? 482 ASN D CB  1 
ATOM   16252 C CG  . ASN D 1 422 ? -9.556   -5.781  -4.830  1.00 71.48  ? 482 ASN D CG  1 
ATOM   16253 O OD1 . ASN D 1 422 ? -8.867   -6.208  -3.916  1.00 109.11 ? 482 ASN D OD1 1 
ATOM   16254 N ND2 . ASN D 1 422 ? -9.810   -4.499  -5.045  1.00 82.81  ? 482 ASN D ND2 1 
ATOM   16255 N N   . GLU D 1 423 ? -9.065   -9.185  -7.695  1.00 61.27  ? 483 GLU D N   1 
ATOM   16256 C CA  . GLU D 1 423 ? -9.449   -10.493 -8.275  1.00 60.35  ? 483 GLU D CA  1 
ATOM   16257 C C   . GLU D 1 423 ? -10.526  -11.128 -7.398  1.00 55.06  ? 483 GLU D C   1 
ATOM   16258 O O   . GLU D 1 423 ? -11.395  -11.780 -7.977  1.00 59.07  ? 483 GLU D O   1 
ATOM   16259 C CB  . GLU D 1 423 ? -8.232   -11.393 -8.435  1.00 73.67  ? 483 GLU D CB  1 
ATOM   16260 C CG  . GLU D 1 423 ? -8.556   -12.870 -8.306  1.00 91.38  ? 483 GLU D CG  1 
ATOM   16261 C CD  . GLU D 1 423 ? -7.955   -13.771 -9.355  1.00 106.06 ? 483 GLU D CD  1 
ATOM   16262 O OE1 . GLU D 1 423 ? -6.717   -13.663 -9.606  1.00 115.65 ? 483 GLU D OE1 1 
ATOM   16263 O OE2 . GLU D 1 423 ? -8.738   -14.593 -9.903  1.00 118.97 ? 483 GLU D OE2 1 
ATOM   16264 N N   . ARG D 1 424 ? -10.467  -10.960 -6.076  1.00 59.03  ? 484 ARG D N   1 
ATOM   16265 C CA  . ARG D 1 424 ? -11.505  -11.472 -5.121  1.00 58.79  ? 484 ARG D CA  1 
ATOM   16266 C C   . ARG D 1 424 ? -11.849  -10.350 -4.151  1.00 56.75  ? 484 ARG D C   1 
ATOM   16267 O O   . ARG D 1 424 ? -11.291  -10.322 -3.067  1.00 61.09  ? 484 ARG D O   1 
ATOM   16268 C CB  . ARG D 1 424 ? -11.008  -12.712 -4.370  1.00 49.23  ? 484 ARG D CB  1 
ATOM   16269 C CG  . ARG D 1 424 ? -10.410  -13.765 -5.281  1.00 49.64  ? 484 ARG D CG  1 
ATOM   16270 C CD  . ARG D 1 424 ? -11.500  -14.604 -5.892  1.00 54.89  ? 484 ARG D CD  1 
ATOM   16271 N NE  . ARG D 1 424 ? -11.663  -15.811 -5.106  1.00 54.42  ? 484 ARG D NE  1 
ATOM   16272 C CZ  . ARG D 1 424 ? -12.823  -16.367 -4.767  1.00 60.55  ? 484 ARG D CZ  1 
ATOM   16273 N NH1 . ARG D 1 424 ? -13.982  -15.838 -5.120  1.00 57.30  ? 484 ARG D NH1 1 
ATOM   16274 N NH2 . ARG D 1 424 ? -12.821  -17.495 -4.081  1.00 75.80  ? 484 ARG D NH2 1 
ATOM   16275 N N   . PRO D 1 425 ? -12.703  -9.357  -4.518  1.00 56.81  ? 485 PRO D N   1 
ATOM   16276 C CA  . PRO D 1 425 ? -13.005  -8.234  -3.622  1.00 53.88  ? 485 PRO D CA  1 
ATOM   16277 C C   . PRO D 1 425 ? -13.858  -8.648  -2.410  1.00 54.01  ? 485 PRO D C   1 
ATOM   16278 O O   . PRO D 1 425 ? -14.847  -9.352  -2.542  1.00 54.34  ? 485 PRO D O   1 
ATOM   16279 C CB  . PRO D 1 425 ? -13.757  -7.214  -4.493  1.00 53.95  ? 485 PRO D CB  1 
ATOM   16280 C CG  . PRO D 1 425 ? -14.313  -8.034  -5.655  1.00 54.96  ? 485 PRO D CG  1 
ATOM   16281 C CD  . PRO D 1 425 ? -13.401  -9.241  -5.813  1.00 54.96  ? 485 PRO D CD  1 
ATOM   16282 N N   . ILE D 1 426 ? -13.435  -8.207  -1.226  1.00 59.40  ? 486 ILE D N   1 
ATOM   16283 C CA  . ILE D 1 426 ? -14.156  -8.417  0.057   1.00 60.28  ? 486 ILE D CA  1 
ATOM   16284 C C   . ILE D 1 426 ? -15.214  -7.306  0.161   1.00 60.53  ? 486 ILE D C   1 
ATOM   16285 O O   . ILE D 1 426 ? -14.842  -6.107  0.315   1.00 48.58  ? 486 ILE D O   1 
ATOM   16286 C CB  . ILE D 1 426 ? -13.161  -8.475  1.229   1.00 57.91  ? 486 ILE D CB  1 
ATOM   16287 C CG1 . ILE D 1 426 ? -12.406  -9.806  1.225   1.00 56.58  ? 486 ILE D CG1 1 
ATOM   16288 C CG2 . ILE D 1 426 ? -13.860  -8.268  2.558   1.00 61.07  ? 486 ILE D CG2 1 
ATOM   16289 C CD1 . ILE D 1 426 ? -11.029  -9.717  1.811   1.00 56.95  ? 486 ILE D CD1 1 
ATOM   16290 N N   . ILE D 1 427 ? -16.483  -7.710  0.022   1.00 63.63  ? 487 ILE D N   1 
ATOM   16291 C CA  . ILE D 1 427 ? -17.673  -6.824  0.162   1.00 60.70  ? 487 ILE D CA  1 
ATOM   16292 C C   . ILE D 1 427 ? -18.475  -7.307  1.370   1.00 53.98  ? 487 ILE D C   1 
ATOM   16293 O O   . ILE D 1 427 ? -18.917  -8.493  1.386   1.00 39.21  ? 487 ILE D O   1 
ATOM   16294 C CB  . ILE D 1 427 ? -18.546  -6.789  -1.113  1.00 70.69  ? 487 ILE D CB  1 
ATOM   16295 C CG1 . ILE D 1 427 ? -17.732  -6.679  -2.405  1.00 66.20  ? 487 ILE D CG1 1 
ATOM   16296 C CG2 . ILE D 1 427 ? -19.587  -5.675  -1.018  1.00 72.57  ? 487 ILE D CG2 1 
ATOM   16297 C CD1 . ILE D 1 427 ? -16.934  -5.424  -2.520  1.00 65.36  ? 487 ILE D CD1 1 
ATOM   16298 N N   . PHE D 1 428 ? -18.641  -6.381  2.319   1.00 51.30  ? 488 PHE D N   1 
ATOM   16299 C CA  . PHE D 1 428 ? -19.362  -6.535  3.598   1.00 50.52  ? 488 PHE D CA  1 
ATOM   16300 C C   . PHE D 1 428 ? -20.494  -5.500  3.592   1.00 47.61  ? 488 PHE D C   1 
ATOM   16301 O O   . PHE D 1 428 ? -20.238  -4.288  3.761   1.00 37.96  ? 488 PHE D O   1 
ATOM   16302 C CB  . PHE D 1 428 ? -18.381  -6.371  4.769   1.00 53.55  ? 488 PHE D CB  1 
ATOM   16303 C CG  . PHE D 1 428 ? -17.667  -7.621  5.217   1.00 52.78  ? 488 PHE D CG  1 
ATOM   16304 C CD1 . PHE D 1 428 ? -17.511  -8.713  4.379   1.00 56.70  ? 488 PHE D CD1 1 
ATOM   16305 C CD2 . PHE D 1 428 ? -17.059  -7.672  6.462   1.00 61.68  ? 488 PHE D CD2 1 
ATOM   16306 C CE1 . PHE D 1 428 ? -16.798  -9.841  4.790   1.00 62.80  ? 488 PHE D CE1 1 
ATOM   16307 C CE2 . PHE D 1 428 ? -16.343  -8.799  6.871   1.00 70.86  ? 488 PHE D CE2 1 
ATOM   16308 C CZ  . PHE D 1 428 ? -16.221  -9.892  6.039   1.00 69.16  ? 488 PHE D CZ  1 
ATOM   16309 N N   . SER D 1 429 ? -21.718  -6.004  3.450   1.00 57.62  ? 489 SER D N   1 
ATOM   16310 C CA  . SER D 1 429 ? -22.989  -5.242  3.480   1.00 58.71  ? 489 SER D CA  1 
ATOM   16311 C C   . SER D 1 429 ? -23.653  -5.429  4.851   1.00 52.35  ? 489 SER D C   1 
ATOM   16312 O O   . SER D 1 429 ? -24.440  -6.378  5.035   1.00 47.56  ? 489 SER D O   1 
ATOM   16313 C CB  . SER D 1 429 ? -23.862  -5.686  2.352   1.00 58.62  ? 489 SER D CB  1 
ATOM   16314 O OG  . SER D 1 429 ? -24.967  -4.809  2.212   1.00 60.59  ? 489 SER D OG  1 
ATOM   16315 N N   . LEU D 1 430 ? -23.326  -4.549  5.790   1.00 51.74  ? 490 LEU D N   1 
ATOM   16316 C CA  . LEU D 1 430 ? -23.579  -4.816  7.229   1.00 63.50  ? 490 LEU D CA  1 
ATOM   16317 C C   . LEU D 1 430 ? -24.968  -4.313  7.633   1.00 58.13  ? 490 LEU D C   1 
ATOM   16318 O O   . LEU D 1 430 ? -25.563  -4.940  8.507   1.00 56.28  ? 490 LEU D O   1 
ATOM   16319 C CB  . LEU D 1 430 ? -22.502  -4.164  8.108   1.00 67.63  ? 490 LEU D CB  1 
ATOM   16320 C CG  . LEU D 1 430 ? -21.158  -4.891  8.222   1.00 63.43  ? 490 LEU D CG  1 
ATOM   16321 C CD1 . LEU D 1 430 ? -21.280  -6.412  8.315   1.00 56.95  ? 490 LEU D CD1 1 
ATOM   16322 C CD2 . LEU D 1 430 ? -20.327  -4.527  7.026   1.00 75.43  ? 490 LEU D CD2 1 
ATOM   16323 N N   . SER D 1 431 ? -25.467  -3.238  7.028   1.00 55.11  ? 491 SER D N   1 
ATOM   16324 C CA  . SER D 1 431 ? -26.712  -2.570  7.470   1.00 56.55  ? 491 SER D CA  1 
ATOM   16325 C C   . SER D 1 431 ? -27.854  -3.587  7.532   1.00 58.63  ? 491 SER D C   1 
ATOM   16326 O O   . SER D 1 431 ? -27.826  -4.588  6.766   1.00 65.39  ? 491 SER D O   1 
ATOM   16327 C CB  . SER D 1 431 ? -27.067  -1.384  6.599   1.00 53.48  ? 491 SER D CB  1 
ATOM   16328 O OG  . SER D 1 431 ? -26.155  -0.336  6.806   1.00 57.73  ? 491 SER D OG  1 
ATOM   16329 N N   . ASN D 1 432 ? -28.807  -3.320  8.440   1.00 55.70  ? 492 ASN D N   1 
ATOM   16330 C CA  . ASN D 1 432 ? -30.033  -4.109  8.694   1.00 52.02  ? 492 ASN D CA  1 
ATOM   16331 C C   . ASN D 1 432 ? -31.226  -3.156  8.773   1.00 55.00  ? 492 ASN D C   1 
ATOM   16332 O O   . ASN D 1 432 ? -31.102  -1.967  9.096   1.00 56.59  ? 492 ASN D O   1 
ATOM   16333 C CB  . ASN D 1 432 ? -29.903  -4.895  10.004  1.00 57.57  ? 492 ASN D CB  1 
ATOM   16334 C CG  . ASN D 1 432 ? -28.778  -5.903  9.989   1.00 49.35  ? 492 ASN D CG  1 
ATOM   16335 O OD1 . ASN D 1 432 ? -28.666  -6.684  9.046   1.00 52.67  ? 492 ASN D OD1 1 
ATOM   16336 N ND2 . ASN D 1 432 ? -27.966  -5.887  11.032  1.00 37.63  ? 492 ASN D ND2 1 
ATOM   16337 N N   . PRO D 1 433 ? -32.455  -3.660  8.535   1.00 57.70  ? 493 PRO D N   1 
ATOM   16338 C CA  . PRO D 1 433 ? -32.677  -5.050  8.144   1.00 52.40  ? 493 PRO D CA  1 
ATOM   16339 C C   . PRO D 1 433 ? -32.425  -5.213  6.633   1.00 51.94  ? 493 PRO D C   1 
ATOM   16340 O O   . PRO D 1 433 ? -31.831  -4.323  6.051   1.00 52.45  ? 493 PRO D O   1 
ATOM   16341 C CB  . PRO D 1 433 ? -34.138  -5.282  8.536   1.00 54.77  ? 493 PRO D CB  1 
ATOM   16342 C CG  . PRO D 1 433 ? -34.746  -3.938  8.880   1.00 55.15  ? 493 PRO D CG  1 
ATOM   16343 C CD  . PRO D 1 433 ? -33.701  -2.885  8.593   1.00 58.88  ? 493 PRO D CD  1 
ATOM   16344 N N   . THR D 1 434 ? -32.893  -6.312  6.030   1.00 51.34  ? 494 THR D N   1 
ATOM   16345 C CA  . THR D 1 434 ? -32.670  -6.710  4.609   1.00 47.70  ? 494 THR D CA  1 
ATOM   16346 C C   . THR D 1 434 ? -32.946  -5.515  3.684   1.00 46.40  ? 494 THR D C   1 
ATOM   16347 O O   . THR D 1 434 ? -32.122  -5.242  2.837   1.00 56.74  ? 494 THR D O   1 
ATOM   16348 C CB  . THR D 1 434 ? -33.509  -7.943  4.225   1.00 40.58  ? 494 THR D CB  1 
ATOM   16349 O OG1 . THR D 1 434 ? -33.344  -8.962  5.212   1.00 35.78  ? 494 THR D OG1 1 
ATOM   16350 C CG2 . THR D 1 434 ? -33.096  -8.516  2.891   1.00 39.84  ? 494 THR D CG2 1 
ATOM   16351 N N   . SER D 1 435 ? -34.047  -4.808  3.870   1.00 51.24  ? 495 SER D N   1 
ATOM   16352 C CA  . SER D 1 435 ? -34.469  -3.639  3.055   1.00 49.75  ? 495 SER D CA  1 
ATOM   16353 C C   . SER D 1 435 ? -33.435  -2.506  3.105   1.00 47.51  ? 495 SER D C   1 
ATOM   16354 O O   . SER D 1 435 ? -33.467  -1.656  2.194   1.00 46.94  ? 495 SER D O   1 
ATOM   16355 C CB  . SER D 1 435 ? -35.790  -3.129  3.537   1.00 53.72  ? 495 SER D CB  1 
ATOM   16356 O OG  . SER D 1 435 ? -35.607  -2.463  4.777   1.00 62.74  ? 495 SER D OG  1 
ATOM   16357 N N   . HIS D 1 436 ? -32.573  -2.446  4.124   1.00 43.26  ? 496 HIS D N   1 
ATOM   16358 C CA  . HIS D 1 436 ? -31.511  -1.406  4.203   1.00 46.53  ? 496 HIS D CA  1 
ATOM   16359 C C   . HIS D 1 436 ? -30.104  -1.956  3.880   1.00 51.36  ? 496 HIS D C   1 
ATOM   16360 O O   . HIS D 1 436 ? -29.147  -1.141  3.907   1.00 40.26  ? 496 HIS D O   1 
ATOM   16361 C CB  . HIS D 1 436 ? -31.625  -0.696  5.540   1.00 48.43  ? 496 HIS D CB  1 
ATOM   16362 C CG  . HIS D 1 436 ? -32.723  0.310   5.522   1.00 58.66  ? 496 HIS D CG  1 
ATOM   16363 N ND1 . HIS D 1 436 ? -33.963  0.065   6.066   1.00 61.47  ? 496 HIS D ND1 1 
ATOM   16364 C CD2 . HIS D 1 436 ? -32.796  1.526   4.941   1.00 70.57  ? 496 HIS D CD2 1 
ATOM   16365 C CE1 . HIS D 1 436 ? -34.728  1.119   5.891   1.00 66.70  ? 496 HIS D CE1 1 
ATOM   16366 N NE2 . HIS D 1 436 ? -34.031  2.035   5.221   1.00 69.37  ? 496 HIS D NE2 1 
ATOM   16367 N N   . SER D 1 437 ? -29.972  -3.266  3.582   1.00 56.84  ? 497 SER D N   1 
ATOM   16368 C CA  . SER D 1 437 ? -28.733  -3.924  3.084   1.00 54.12  ? 497 SER D CA  1 
ATOM   16369 C C   . SER D 1 437 ? -28.179  -3.076  1.926   1.00 53.42  ? 497 SER D C   1 
ATOM   16370 O O   . SER D 1 437 ? -28.962  -2.753  1.010   1.00 55.45  ? 497 SER D O   1 
ATOM   16371 C CB  . SER D 1 437 ? -28.989  -5.386  2.672   1.00 51.43  ? 497 SER D CB  1 
ATOM   16372 O OG  . SER D 1 437 ? -27.816  -6.209  2.750   1.00 53.30  ? 497 SER D OG  1 
ATOM   16373 N N   . GLU D 1 438 ? -26.887  -2.744  1.959   1.00 52.63  ? 498 GLU D N   1 
ATOM   16374 C CA  . GLU D 1 438 ? -26.190  -1.934  0.917   1.00 59.88  ? 498 GLU D CA  1 
ATOM   16375 C C   . GLU D 1 438 ? -26.201  -2.671  -0.440  1.00 58.34  ? 498 GLU D C   1 
ATOM   16376 O O   . GLU D 1 438 ? -26.154  -1.994  -1.491  1.00 54.79  ? 498 GLU D O   1 
ATOM   16377 C CB  . GLU D 1 438 ? -24.771  -1.615  1.389   1.00 59.46  ? 498 GLU D CB  1 
ATOM   16378 C CG  . GLU D 1 438 ? -24.709  -0.583  2.506   1.00 61.15  ? 498 GLU D CG  1 
ATOM   16379 C CD  . GLU D 1 438 ? -24.739  -1.098  3.941   1.00 66.55  ? 498 GLU D CD  1 
ATOM   16380 O OE1 . GLU D 1 438 ? -24.775  -2.360  4.173   1.00 58.08  ? 498 GLU D OE1 1 
ATOM   16381 O OE2 . GLU D 1 438 ? -24.726  -0.216  4.843   1.00 67.92  ? 498 GLU D OE2 1 
ATOM   16382 N N   . CYS D 1 439 ? -26.245  -4.005  -0.433  1.00 48.01  ? 499 CYS D N   1 
ATOM   16383 C CA  . CYS D 1 439 ? -26.612  -4.809  -1.616  1.00 52.23  ? 499 CYS D CA  1 
ATOM   16384 C C   . CYS D 1 439 ? -27.158  -6.144  -1.128  1.00 62.96  ? 499 CYS D C   1 
ATOM   16385 O O   . CYS D 1 439 ? -27.040  -6.383  0.083   1.00 60.10  ? 499 CYS D O   1 
ATOM   16386 C CB  . CYS D 1 439 ? -25.454  -4.985  -2.588  1.00 51.94  ? 499 CYS D CB  1 
ATOM   16387 S SG  . CYS D 1 439 ? -24.021  -5.862  -1.927  1.00 65.18  ? 499 CYS D SG  1 
ATOM   16388 N N   . THR D 1 440 ? -27.777  -6.919  -2.033  1.00 63.48  ? 500 THR D N   1 
ATOM   16389 C CA  . THR D 1 440 ? -28.233  -8.307  -1.800  1.00 54.33  ? 500 THR D CA  1 
ATOM   16390 C C   . THR D 1 440 ? -27.036  -9.228  -2.030  1.00 50.00  ? 500 THR D C   1 
ATOM   16391 O O   . THR D 1 440 ? -26.056  -8.773  -2.630  1.00 36.61  ? 500 THR D O   1 
ATOM   16392 C CB  . THR D 1 440 ? -29.386  -8.696  -2.741  1.00 63.28  ? 500 THR D CB  1 
ATOM   16393 O OG1 . THR D 1 440 ? -28.906  -9.018  -4.044  1.00 68.47  ? 500 THR D OG1 1 
ATOM   16394 C CG2 . THR D 1 440 ? -30.420  -7.610  -2.915  1.00 67.11  ? 500 THR D CG2 1 
ATOM   16395 N N   . ALA D 1 441 ? -27.150  -10.495 -1.620  1.00 53.68  ? 501 ALA D N   1 
ATOM   16396 C CA  . ALA D 1 441 ? -26.202  -11.574 -1.976  1.00 52.88  ? 501 ALA D CA  1 
ATOM   16397 C C   . ALA D 1 441 ? -26.279  -11.845 -3.475  1.00 52.22  ? 501 ALA D C   1 
ATOM   16398 O O   . ALA D 1 441 ? -25.228  -12.064 -4.068  1.00 54.52  ? 501 ALA D O   1 
ATOM   16399 C CB  . ALA D 1 441 ? -26.488  -12.829 -1.198  1.00 59.65  ? 501 ALA D CB  1 
ATOM   16400 N N   . GLU D 1 442 ? -27.476  -11.838 -4.067  1.00 58.73  ? 502 GLU D N   1 
ATOM   16401 C CA  . GLU D 1 442 ? -27.697  -12.031 -5.532  1.00 59.64  ? 502 GLU D CA  1 
ATOM   16402 C C   . GLU D 1 442 ? -26.866  -10.994 -6.323  1.00 52.62  ? 502 GLU D C   1 
ATOM   16403 O O   . GLU D 1 442 ? -26.153  -11.405 -7.260  1.00 43.54  ? 502 GLU D O   1 
ATOM   16404 C CB  . GLU D 1 442 ? -29.220  -11.942 -5.790  1.00 63.88  ? 502 GLU D CB  1 
ATOM   16405 C CG  . GLU D 1 442 ? -29.732  -12.485 -7.118  1.00 64.30  ? 502 GLU D CG  1 
ATOM   16406 C CD  . GLU D 1 442 ? -29.696  -13.999 -7.256  1.00 66.91  ? 502 GLU D CD  1 
ATOM   16407 O OE1 . GLU D 1 442 ? -30.035  -14.744 -6.297  1.00 64.81  ? 502 GLU D OE1 1 
ATOM   16408 O OE2 . GLU D 1 442 ? -29.246  -14.431 -8.302  1.00 71.50  ? 502 GLU D OE2 1 
ATOM   16409 N N   . GLN D 1 443 ? -26.961  -9.703  -5.965  1.00 56.65  ? 503 GLN D N   1 
ATOM   16410 C CA  . GLN D 1 443 ? -26.330  -8.575  -6.708  1.00 52.02  ? 503 GLN D CA  1 
ATOM   16411 C C   . GLN D 1 443 ? -24.793  -8.718  -6.659  1.00 60.73  ? 503 GLN D C   1 
ATOM   16412 O O   . GLN D 1 443 ? -24.147  -8.594  -7.723  1.00 53.83  ? 503 GLN D O   1 
ATOM   16413 C CB  . GLN D 1 443 ? -26.764  -7.239  -6.102  1.00 48.21  ? 503 GLN D CB  1 
ATOM   16414 C CG  . GLN D 1 443 ? -28.228  -6.930  -6.304  1.00 48.82  ? 503 GLN D CG  1 
ATOM   16415 C CD  . GLN D 1 443 ? -28.693  -5.721  -5.536  1.00 51.70  ? 503 GLN D CD  1 
ATOM   16416 O OE1 . GLN D 1 443 ? -28.039  -5.267  -4.596  1.00 56.73  ? 503 GLN D OE1 1 
ATOM   16417 N NE2 . GLN D 1 443 ? -29.840  -5.186  -5.953  1.00 51.58  ? 503 GLN D NE2 1 
ATOM   16418 N N   . ALA D 1 444 ? -24.240  -8.978  -5.463  1.00 58.68  ? 504 ALA D N   1 
ATOM   16419 C CA  . ALA D 1 444 ? -22.790  -9.025  -5.158  1.00 55.75  ? 504 ALA D CA  1 
ATOM   16420 C C   . ALA D 1 444 ? -22.083  -10.133 -5.937  1.00 57.03  ? 504 ALA D C   1 
ATOM   16421 O O   . ALA D 1 444 ? -20.984  -9.865  -6.448  1.00 54.63  ? 504 ALA D O   1 
ATOM   16422 C CB  . ALA D 1 444 ? -22.594  -9.248  -3.693  1.00 65.38  ? 504 ALA D CB  1 
ATOM   16423 N N   . TYR D 1 445 ? -22.676  -11.332 -5.988  1.00 52.43  ? 505 TYR D N   1 
ATOM   16424 C CA  . TYR D 1 445 ? -22.143  -12.492 -6.752  1.00 55.27  ? 505 TYR D CA  1 
ATOM   16425 C C   . TYR D 1 445 ? -22.337  -12.318 -8.278  1.00 56.09  ? 505 TYR D C   1 
ATOM   16426 O O   . TYR D 1 445 ? -21.441  -12.745 -9.059  1.00 57.42  ? 505 TYR D O   1 
ATOM   16427 C CB  . TYR D 1 445 ? -22.732  -13.806 -6.227  1.00 53.81  ? 505 TYR D CB  1 
ATOM   16428 C CG  . TYR D 1 445 ? -22.292  -14.163 -4.824  1.00 53.77  ? 505 TYR D CG  1 
ATOM   16429 C CD1 . TYR D 1 445 ? -20.955  -14.304 -4.499  1.00 54.29  ? 505 TYR D CD1 1 
ATOM   16430 C CD2 . TYR D 1 445 ? -23.222  -14.399 -3.822  1.00 49.41  ? 505 TYR D CD2 1 
ATOM   16431 C CE1 . TYR D 1 445 ? -20.562  -14.615 -3.209  1.00 57.72  ? 505 TYR D CE1 1 
ATOM   16432 C CE2 . TYR D 1 445 ? -22.843  -14.739 -2.538  1.00 42.94  ? 505 TYR D CE2 1 
ATOM   16433 C CZ  . TYR D 1 445 ? -21.506  -14.851 -2.224  1.00 47.23  ? 505 TYR D CZ  1 
ATOM   16434 O OH  . TYR D 1 445 ? -21.068  -15.162 -0.963  1.00 43.69  ? 505 TYR D OH  1 
ATOM   16435 N N   . THR D 1 446 ? -23.444  -11.712 -8.724  1.00 55.05  ? 506 THR D N   1 
ATOM   16436 C CA  . THR D 1 446 ? -23.706  -11.445 -10.165 1.00 58.60  ? 506 THR D CA  1 
ATOM   16437 C C   . THR D 1 446 ? -22.772  -10.342 -10.668 1.00 59.56  ? 506 THR D C   1 
ATOM   16438 O O   . THR D 1 446 ? -22.033  -10.610 -11.615 1.00 74.68  ? 506 THR D O   1 
ATOM   16439 C CB  . THR D 1 446 ? -25.179  -11.115 -10.409 1.00 60.42  ? 506 THR D CB  1 
ATOM   16440 O OG1 . THR D 1 446 ? -25.912  -12.065 -9.648  1.00 65.73  ? 506 THR D OG1 1 
ATOM   16441 C CG2 . THR D 1 446 ? -25.617  -11.232 -11.847 1.00 64.70  ? 506 THR D CG2 1 
ATOM   16442 N N   . TRP D 1 447 ? -22.765  -9.170  -10.031 1.00 59.66  ? 507 TRP D N   1 
ATOM   16443 C CA  . TRP D 1 447 ? -22.025  -7.954  -10.483 1.00 59.51  ? 507 TRP D CA  1 
ATOM   16444 C C   . TRP D 1 447 ? -20.503  -8.106  -10.326 1.00 62.57  ? 507 TRP D C   1 
ATOM   16445 O O   . TRP D 1 447 ? -19.759  -7.206  -10.822 1.00 66.64  ? 507 TRP D O   1 
ATOM   16446 C CB  . TRP D 1 447 ? -22.546  -6.725  -9.729  1.00 61.54  ? 507 TRP D CB  1 
ATOM   16447 C CG  . TRP D 1 447 ? -23.996  -6.436  -9.980  1.00 59.56  ? 507 TRP D CG  1 
ATOM   16448 C CD1 . TRP D 1 447 ? -24.757  -6.893  -11.021 1.00 52.72  ? 507 TRP D CD1 1 
ATOM   16449 C CD2 . TRP D 1 447 ? -24.859  -5.605  -9.176  1.00 57.28  ? 507 TRP D CD2 1 
ATOM   16450 N NE1 . TRP D 1 447 ? -26.029  -6.404  -10.919 1.00 59.09  ? 507 TRP D NE1 1 
ATOM   16451 C CE2 . TRP D 1 447 ? -26.121  -5.599  -9.808  1.00 58.42  ? 507 TRP D CE2 1 
ATOM   16452 C CE3 . TRP D 1 447 ? -24.696  -4.873  -7.993  1.00 56.71  ? 507 TRP D CE3 1 
ATOM   16453 C CZ2 . TRP D 1 447 ? -27.199  -4.869  -9.302  1.00 59.63  ? 507 TRP D CZ2 1 
ATOM   16454 C CZ3 . TRP D 1 447 ? -25.767  -4.166  -7.486  1.00 60.48  ? 507 TRP D CZ3 1 
ATOM   16455 C CH2 . TRP D 1 447 ? -27.003  -4.168  -8.133  1.00 60.21  ? 507 TRP D CH2 1 
ATOM   16456 N N   . SER D 1 448 ? -20.048  -9.185  -9.676  1.00 57.21  ? 508 SER D N   1 
ATOM   16457 C CA  . SER D 1 448 ? -18.612  -9.489  -9.462  1.00 61.89  ? 508 SER D CA  1 
ATOM   16458 C C   . SER D 1 448 ? -18.217  -10.779 -10.168 1.00 59.55  ? 508 SER D C   1 
ATOM   16459 O O   . SER D 1 448 ? -17.113  -11.265 -9.854  1.00 59.99  ? 508 SER D O   1 
ATOM   16460 C CB  . SER D 1 448 ? -18.271  -9.641  -8.019  1.00 65.57  ? 508 SER D CB  1 
ATOM   16461 O OG  . SER D 1 448 ? -18.591  -10.967 -7.594  1.00 66.08  ? 508 SER D OG  1 
ATOM   16462 N N   . GLN D 1 449 ? -19.072  -11.318 -11.040 1.00 59.18  ? 509 GLN D N   1 
ATOM   16463 C CA  . GLN D 1 449 ? -18.835  -12.562 -11.823 1.00 63.40  ? 509 GLN D CA  1 
ATOM   16464 C C   . GLN D 1 449 ? -18.425  -13.723 -10.891 1.00 59.79  ? 509 GLN D C   1 
ATOM   16465 O O   . GLN D 1 449 ? -17.590  -14.541 -11.294 1.00 66.43  ? 509 GLN D O   1 
ATOM   16466 C CB  . GLN D 1 449 ? -17.829  -12.289 -12.944 1.00 67.21  ? 509 GLN D CB  1 
ATOM   16467 C CG  . GLN D 1 449 ? -18.288  -11.249 -13.961 1.00 64.43  ? 509 GLN D CG  1 
ATOM   16468 C CD  . GLN D 1 449 ? -17.150  -10.651 -14.758 1.00 65.84  ? 509 GLN D CD  1 
ATOM   16469 O OE1 . GLN D 1 449 ? -15.983  -11.053 -14.694 1.00 58.53  ? 509 GLN D OE1 1 
ATOM   16470 N NE2 . GLN D 1 449 ? -17.493  -9.645  -15.534 1.00 71.23  ? 509 GLN D NE2 1 
ATOM   16471 N N   . GLY D 1 450 ? -19.021  -13.824 -9.700  1.00 59.20  ? 510 GLY D N   1 
ATOM   16472 C CA  . GLY D 1 450 ? -18.824  -14.955 -8.774  1.00 63.21  ? 510 GLY D CA  1 
ATOM   16473 C C   . GLY D 1 450 ? -17.488  -14.904 -8.054  1.00 60.37  ? 510 GLY D C   1 
ATOM   16474 O O   . GLY D 1 450 ? -17.076  -15.947 -7.506  1.00 57.61  ? 510 GLY D O   1 
ATOM   16475 N N   . ARG D 1 451 ? -16.851  -13.736 -8.008  1.00 63.31  ? 511 ARG D N   1 
ATOM   16476 C CA  . ARG D 1 451 ? -15.447  -13.592 -7.530  1.00 74.06  ? 511 ARG D CA  1 
ATOM   16477 C C   . ARG D 1 451 ? -15.384  -12.882 -6.165  1.00 70.88  ? 511 ARG D C   1 
ATOM   16478 O O   . ARG D 1 451 ? -14.281  -12.890 -5.544  1.00 68.70  ? 511 ARG D O   1 
ATOM   16479 C CB  . ARG D 1 451 ? -14.590  -12.854 -8.575  1.00 80.56  ? 511 ARG D CB  1 
ATOM   16480 C CG  . ARG D 1 451 ? -14.265  -13.652 -9.839  1.00 75.73  ? 511 ARG D CG  1 
ATOM   16481 C CD  . ARG D 1 451 ? -13.216  -12.955 -10.700 1.00 65.42  ? 511 ARG D CD  1 
ATOM   16482 N NE  . ARG D 1 451 ? -13.648  -11.748 -11.411 1.00 54.62  ? 511 ARG D NE  1 
ATOM   16483 C CZ  . ARG D 1 451 ? -13.448  -10.481 -11.040 1.00 50.31  ? 511 ARG D CZ  1 
ATOM   16484 N NH1 . ARG D 1 451 ? -12.829  -10.154 -9.930  1.00 50.14  ? 511 ARG D NH1 1 
ATOM   16485 N NH2 . ARG D 1 451 ? -13.865  -9.502  -11.817 1.00 61.34  ? 511 ARG D NH2 1 
ATOM   16486 N N   . SER D 1 452 ? -16.477  -12.265 -5.704  1.00 75.29  ? 512 SER D N   1 
ATOM   16487 C CA  . SER D 1 452 ? -16.521  -11.538 -4.402  1.00 70.82  ? 512 SER D CA  1 
ATOM   16488 C C   . SER D 1 452 ? -16.568  -12.543 -3.244  1.00 69.57  ? 512 SER D C   1 
ATOM   16489 O O   . SER D 1 452 ? -17.149  -13.646 -3.395  1.00 58.50  ? 512 SER D O   1 
ATOM   16490 C CB  . SER D 1 452 ? -17.679  -10.581 -4.299  1.00 64.63  ? 512 SER D CB  1 
ATOM   16491 O OG  . SER D 1 452 ? -18.906  -11.293 -4.327  1.00 60.38  ? 512 SER D OG  1 
ATOM   16492 N N   . ILE D 1 453 ? -15.897  -12.174 -2.150  1.00 69.16  ? 513 ILE D N   1 
ATOM   16493 C CA  . ILE D 1 453 ? -16.118  -12.706 -0.780  1.00 63.93  ? 513 ILE D CA  1 
ATOM   16494 C C   . ILE D 1 453 ? -17.131  -11.778 -0.111  1.00 69.87  ? 513 ILE D C   1 
ATOM   16495 O O   . ILE D 1 453 ? -16.770  -10.618 0.231   1.00 66.19  ? 513 ILE D O   1 
ATOM   16496 C CB  . ILE D 1 453 ? -14.790  -12.808 -0.022  1.00 64.37  ? 513 ILE D CB  1 
ATOM   16497 C CG1 . ILE D 1 453 ? -13.819  -13.758 -0.740  1.00 69.18  ? 513 ILE D CG1 1 
ATOM   16498 C CG2 . ILE D 1 453 ? -15.033  -13.206 1.427   1.00 62.08  ? 513 ILE D CG2 1 
ATOM   16499 C CD1 . ILE D 1 453 ? -14.448  -15.008 -1.372  1.00 64.54  ? 513 ILE D CD1 1 
ATOM   16500 N N   . PHE D 1 454 ? -18.373  -12.263 0.007   1.00 61.76  ? 514 PHE D N   1 
ATOM   16501 C CA  . PHE D 1 454 ? -19.535  -11.461 0.453   1.00 53.02  ? 514 PHE D CA  1 
ATOM   16502 C C   . PHE D 1 454 ? -20.026  -11.969 1.796   1.00 49.78  ? 514 PHE D C   1 
ATOM   16503 O O   . PHE D 1 454 ? -20.130  -13.175 2.031   1.00 53.98  ? 514 PHE D O   1 
ATOM   16504 C CB  . PHE D 1 454 ? -20.695  -11.531 -0.542  1.00 60.09  ? 514 PHE D CB  1 
ATOM   16505 C CG  . PHE D 1 454 ? -21.858  -10.668 -0.148  1.00 58.66  ? 514 PHE D CG  1 
ATOM   16506 C CD1 . PHE D 1 454 ? -21.713  -9.288  -0.129  1.00 60.01  ? 514 PHE D CD1 1 
ATOM   16507 C CD2 . PHE D 1 454 ? -23.064  -11.229 0.273   1.00 65.87  ? 514 PHE D CD2 1 
ATOM   16508 C CE1 . PHE D 1 454 ? -22.773  -8.480  0.270   1.00 62.67  ? 514 PHE D CE1 1 
ATOM   16509 C CE2 . PHE D 1 454 ? -24.123  -10.421 0.670   1.00 65.36  ? 514 PHE D CE2 1 
ATOM   16510 C CZ  . PHE D 1 454 ? -23.976  -9.045  0.661   1.00 64.63  ? 514 PHE D CZ  1 
ATOM   16511 N N   . ALA D 1 455 ? -20.365  -11.021 2.655   1.00 57.30  ? 515 ALA D N   1 
ATOM   16512 C CA  . ALA D 1 455 ? -21.109  -11.254 3.909   1.00 53.59  ? 515 ALA D CA  1 
ATOM   16513 C C   . ALA D 1 455 ? -21.923  -9.993  4.227   1.00 55.68  ? 515 ALA D C   1 
ATOM   16514 O O   . ALA D 1 455 ? -21.536  -8.886  3.732   1.00 46.14  ? 515 ALA D O   1 
ATOM   16515 C CB  . ALA D 1 455 ? -20.124  -11.602 4.997   1.00 52.91  ? 515 ALA D CB  1 
ATOM   16516 N N   . SER D 1 456 ? -23.007  -10.165 5.005   1.00 56.16  ? 516 SER D N   1 
ATOM   16517 C CA  . SER D 1 456 ? -24.030  -9.120  5.280   1.00 50.19  ? 516 SER D CA  1 
ATOM   16518 C C   . SER D 1 456 ? -24.569  -9.269  6.695   1.00 51.85  ? 516 SER D C   1 
ATOM   16519 O O   . SER D 1 456 ? -24.394  -10.387 7.273   1.00 46.97  ? 516 SER D O   1 
ATOM   16520 C CB  . SER D 1 456 ? -25.155  -9.190  4.278   1.00 54.78  ? 516 SER D CB  1 
ATOM   16521 O OG  . SER D 1 456 ? -25.882  -10.413 4.381   1.00 53.60  ? 516 SER D OG  1 
ATOM   16522 N N   . GLY D 1 457 ? -25.246  -8.212  7.180   1.00 48.60  ? 517 GLY D N   1 
ATOM   16523 C CA  . GLY D 1 457 ? -25.885  -8.171  8.511   1.00 52.32  ? 517 GLY D CA  1 
ATOM   16524 C C   . GLY D 1 457 ? -27.118  -9.067  8.625   1.00 59.34  ? 517 GLY D C   1 
ATOM   16525 O O   . GLY D 1 457 ? -27.323  -9.733  9.684   1.00 51.87  ? 517 GLY D O   1 
ATOM   16526 N N   . SER D 1 458 ? -27.958  -9.064  7.594   1.00 65.29  ? 518 SER D N   1 
ATOM   16527 C CA  . SER D 1 458 ? -29.260  -9.771  7.590   1.00 57.42  ? 518 SER D CA  1 
ATOM   16528 C C   . SER D 1 458 ? -29.143  -11.024 6.731   1.00 55.99  ? 518 SER D C   1 
ATOM   16529 O O   . SER D 1 458 ? -28.395  -11.029 5.765   1.00 53.51  ? 518 SER D O   1 
ATOM   16530 C CB  . SER D 1 458 ? -30.308  -8.805  7.119   1.00 58.58  ? 518 SER D CB  1 
ATOM   16531 O OG  . SER D 1 458 ? -30.345  -7.674  7.996   1.00 53.73  ? 518 SER D OG  1 
ATOM   16532 N N   . PRO D 1 459 ? -29.853  -12.134 7.030   1.00 62.26  ? 519 PRO D N   1 
ATOM   16533 C CA  . PRO D 1 459 ? -29.642  -13.404 6.320   1.00 60.93  ? 519 PRO D CA  1 
ATOM   16534 C C   . PRO D 1 459 ? -30.125  -13.321 4.868   1.00 53.29  ? 519 PRO D C   1 
ATOM   16535 O O   . PRO D 1 459 ? -31.081  -12.602 4.665   1.00 52.34  ? 519 PRO D O   1 
ATOM   16536 C CB  . PRO D 1 459 ? -30.474  -14.425 7.114   1.00 61.17  ? 519 PRO D CB  1 
ATOM   16537 C CG  . PRO D 1 459 ? -31.561  -13.577 7.720   1.00 63.87  ? 519 PRO D CG  1 
ATOM   16538 C CD  . PRO D 1 459 ? -30.918  -12.234 8.031   1.00 62.93  ? 519 PRO D CD  1 
ATOM   16539 N N   . PHE D 1 460 ? -29.419  -13.987 3.934   1.00 50.16  ? 520 PHE D N   1 
ATOM   16540 C CA  . PHE D 1 460 ? -29.762  -14.176 2.493   1.00 43.95  ? 520 PHE D CA  1 
ATOM   16541 C C   . PHE D 1 460 ? -29.659  -15.655 2.119   1.00 44.68  ? 520 PHE D C   1 
ATOM   16542 O O   . PHE D 1 460 ? -28.742  -16.332 2.532   1.00 44.76  ? 520 PHE D O   1 
ATOM   16543 C CB  . PHE D 1 460 ? -28.835  -13.394 1.573   1.00 39.29  ? 520 PHE D CB  1 
ATOM   16544 C CG  . PHE D 1 460 ? -29.089  -11.913 1.539   1.00 44.38  ? 520 PHE D CG  1 
ATOM   16545 C CD1 . PHE D 1 460 ? -30.149  -11.395 0.815   1.00 49.15  ? 520 PHE D CD1 1 
ATOM   16546 C CD2 . PHE D 1 460 ? -28.259  -11.026 2.212   1.00 48.75  ? 520 PHE D CD2 1 
ATOM   16547 C CE1 . PHE D 1 460 ? -30.382  -10.021 0.776   1.00 56.20  ? 520 PHE D CE1 1 
ATOM   16548 C CE2 . PHE D 1 460 ? -28.480  -9.649  2.162   1.00 50.91  ? 520 PHE D CE2 1 
ATOM   16549 C CZ  . PHE D 1 460 ? -29.553  -9.143  1.455   1.00 53.20  ? 520 PHE D CZ  1 
ATOM   16550 N N   . ALA D 1 461 ? -30.605  -16.169 1.348   1.00 47.95  ? 521 ALA D N   1 
ATOM   16551 C CA  . ALA D 1 461 ? -30.575  -17.592 0.959   1.00 48.07  ? 521 ALA D CA  1 
ATOM   16552 C C   . ALA D 1 461 ? -29.382  -17.798 0.042   1.00 54.65  ? 521 ALA D C   1 
ATOM   16553 O O   . ALA D 1 461 ? -28.887  -16.820 -0.542  1.00 61.97  ? 521 ALA D O   1 
ATOM   16554 C CB  . ALA D 1 461 ? -31.859  -17.975 0.287   1.00 57.36  ? 521 ALA D CB  1 
ATOM   16555 N N   . PRO D 1 462 ? -28.904  -19.056 -0.088  1.00 53.75  ? 522 PRO D N   1 
ATOM   16556 C CA  . PRO D 1 462 ? -27.895  -19.419 -1.081  1.00 56.73  ? 522 PRO D CA  1 
ATOM   16557 C C   . PRO D 1 462 ? -28.213  -18.823 -2.462  1.00 55.33  ? 522 PRO D C   1 
ATOM   16558 O O   . PRO D 1 462 ? -29.375  -18.777 -2.791  1.00 65.76  ? 522 PRO D O   1 
ATOM   16559 C CB  . PRO D 1 462 ? -27.915  -20.964 -1.132  1.00 56.91  ? 522 PRO D CB  1 
ATOM   16560 C CG  . PRO D 1 462 ? -28.719  -21.432 0.088   1.00 56.82  ? 522 PRO D CG  1 
ATOM   16561 C CD  . PRO D 1 462 ? -29.298  -20.194 0.747   1.00 52.81  ? 522 PRO D CD  1 
ATOM   16562 N N   . VAL D 1 463 ? -27.181  -18.394 -3.203  1.00 48.24  ? 523 VAL D N   1 
ATOM   16563 C CA  . VAL D 1 463 ? -27.249  -17.700 -4.531  1.00 52.06  ? 523 VAL D CA  1 
ATOM   16564 C C   . VAL D 1 463 ? -26.586  -18.639 -5.559  1.00 49.61  ? 523 VAL D C   1 
ATOM   16565 O O   . VAL D 1 463 ? -25.515  -19.152 -5.257  1.00 56.58  ? 523 VAL D O   1 
ATOM   16566 C CB  . VAL D 1 463 ? -26.581  -16.285 -4.469  1.00 51.10  ? 523 VAL D CB  1 
ATOM   16567 C CG1 . VAL D 1 463 ? -26.382  -15.637 -5.826  1.00 45.88  ? 523 VAL D CG1 1 
ATOM   16568 C CG2 . VAL D 1 463 ? -27.327  -15.305 -3.578  1.00 51.46  ? 523 VAL D CG2 1 
ATOM   16569 N N   . GLU D 1 464 ? -27.171  -18.845 -6.741  1.00 58.63  ? 524 GLU D N   1 
ATOM   16570 C CA  . GLU D 1 464 ? -26.610  -19.665 -7.854  1.00 58.04  ? 524 GLU D CA  1 
ATOM   16571 C C   . GLU D 1 464 ? -26.068  -18.754 -8.964  1.00 54.57  ? 524 GLU D C   1 
ATOM   16572 O O   . GLU D 1 464 ? -26.755  -17.777 -9.305  1.00 54.01  ? 524 GLU D O   1 
ATOM   16573 C CB  . GLU D 1 464 ? -27.677  -20.626 -8.391  1.00 58.81  ? 524 GLU D CB  1 
ATOM   16574 C CG  . GLU D 1 464 ? -27.844  -21.873 -7.540  1.00 67.71  ? 524 GLU D CG  1 
ATOM   16575 C CD  . GLU D 1 464 ? -26.994  -23.052 -7.983  1.00 84.60  ? 524 GLU D CD  1 
ATOM   16576 O OE1 . GLU D 1 464 ? -25.880  -22.819 -8.500  1.00 94.32  ? 524 GLU D OE1 1 
ATOM   16577 O OE2 . GLU D 1 464 ? -27.455  -24.209 -7.833  1.00 113.76 ? 524 GLU D OE2 1 
ATOM   16578 N N   . TYR D 1 465 ? -24.890  -19.087 -9.526  1.00 55.93  ? 525 TYR D N   1 
ATOM   16579 C CA  . TYR D 1 465 ? -24.154  -18.313 -10.564 1.00 49.72  ? 525 TYR D CA  1 
ATOM   16580 C C   . TYR D 1 465 ? -23.079  -19.188 -11.232 1.00 55.27  ? 525 TYR D C   1 
ATOM   16581 O O   . TYR D 1 465 ? -22.147  -19.712 -10.559 1.00 51.86  ? 525 TYR D O   1 
ATOM   16582 C CB  . TYR D 1 465 ? -23.475  -17.098 -9.928  1.00 57.74  ? 525 TYR D CB  1 
ATOM   16583 C CG  . TYR D 1 465 ? -22.928  -16.136 -10.929 1.00 52.04  ? 525 TYR D CG  1 
ATOM   16584 C CD1 . TYR D 1 465 ? -23.729  -15.143 -11.442 1.00 48.96  ? 525 TYR D CD1 1 
ATOM   16585 C CD2 . TYR D 1 465 ? -21.620  -16.241 -11.355 1.00 56.21  ? 525 TYR D CD2 1 
ATOM   16586 C CE1 . TYR D 1 465 ? -23.239  -14.251 -12.373 1.00 55.61  ? 525 TYR D CE1 1 
ATOM   16587 C CE2 . TYR D 1 465 ? -21.119  -15.377 -12.310 1.00 64.71  ? 525 TYR D CE2 1 
ATOM   16588 C CZ  . TYR D 1 465 ? -21.926  -14.362 -12.803 1.00 64.27  ? 525 TYR D CZ  1 
ATOM   16589 O OH  . TYR D 1 465 ? -21.432  -13.460 -13.710 1.00 66.04  ? 525 TYR D OH  1 
ATOM   16590 N N   . GLU D 1 466 ? -23.188  -19.349 -12.557 1.00 69.43  ? 526 GLU D N   1 
ATOM   16591 C CA  . GLU D 1 466 ? -22.313  -20.203 -13.420 1.00 71.22  ? 526 GLU D CA  1 
ATOM   16592 C C   . GLU D 1 466 ? -22.293  -21.621 -12.823 1.00 70.03  ? 526 GLU D C   1 
ATOM   16593 O O   . GLU D 1 466 ? -21.210  -22.172 -12.674 1.00 88.50  ? 526 GLU D O   1 
ATOM   16594 C CB  . GLU D 1 466 ? -20.916  -19.555 -13.583 1.00 81.15  ? 526 GLU D CB  1 
ATOM   16595 C CG  . GLU D 1 466 ? -20.570  -18.975 -14.962 1.00 87.47  ? 526 GLU D CG  1 
ATOM   16596 C CD  . GLU D 1 466 ? -20.849  -17.495 -15.183 1.00 87.86  ? 526 GLU D CD  1 
ATOM   16597 O OE1 . GLU D 1 466 ? -21.849  -17.017 -14.664 1.00 97.57  ? 526 GLU D OE1 1 
ATOM   16598 O OE2 . GLU D 1 466 ? -20.076  -16.839 -15.895 1.00 88.19  ? 526 GLU D OE2 1 
ATOM   16599 N N   . GLY D 1 467 ? -23.458  -22.168 -12.473 1.00 67.33  ? 527 GLY D N   1 
ATOM   16600 C CA  . GLY D 1 467 ? -23.668  -23.578 -12.118 1.00 71.87  ? 527 GLY D CA  1 
ATOM   16601 C C   . GLY D 1 467 ? -23.082  -23.944 -10.781 1.00 65.32  ? 527 GLY D C   1 
ATOM   16602 O O   . GLY D 1 467 ? -22.867  -25.163 -10.577 1.00 68.29  ? 527 GLY D O   1 
ATOM   16603 N N   . LYS D 1 468 ? -22.856  -22.945 -9.925  1.00 66.03  ? 528 LYS D N   1 
ATOM   16604 C CA  . LYS D 1 468 ? -22.266  -23.115 -8.569  1.00 81.56  ? 528 LYS D CA  1 
ATOM   16605 C C   . LYS D 1 468 ? -23.160  -22.420 -7.526  1.00 81.64  ? 528 LYS D C   1 
ATOM   16606 O O   . LYS D 1 468 ? -23.851  -21.464 -7.902  1.00 78.78  ? 528 LYS D O   1 
ATOM   16607 C CB  . LYS D 1 468 ? -20.812  -22.608 -8.548  1.00 85.68  ? 528 LYS D CB  1 
ATOM   16608 C CG  . LYS D 1 468 ? -19.782  -23.562 -7.903  1.00 101.55 ? 528 LYS D CG  1 
ATOM   16609 C CD  . LYS D 1 468 ? -20.247  -24.471 -6.691  1.00 103.57 ? 528 LYS D CD  1 
ATOM   16610 C CE  . LYS D 1 468 ? -20.892  -25.805 -7.087  1.00 88.80  ? 528 LYS D CE  1 
ATOM   16611 N NZ  . LYS D 1 468 ? -21.974  -26.298 -6.185  1.00 58.20  ? 528 LYS D NZ  1 
ATOM   16612 N N   . THR D 1 469 ? -23.116  -22.876 -6.262  1.00 75.69  ? 529 THR D N   1 
ATOM   16613 C CA  . THR D 1 469 ? -23.860  -22.358 -5.082  1.00 74.09  ? 529 THR D CA  1 
ATOM   16614 C C   . THR D 1 469 ? -22.939  -21.509 -4.184  1.00 60.35  ? 529 THR D C   1 
ATOM   16615 O O   . THR D 1 469 ? -21.903  -21.990 -3.771  1.00 52.04  ? 529 THR D O   1 
ATOM   16616 C CB  . THR D 1 469 ? -24.481  -23.527 -4.303  1.00 75.85  ? 529 THR D CB  1 
ATOM   16617 O OG1 . THR D 1 469 ? -23.533  -23.988 -3.346  1.00 91.69  ? 529 THR D OG1 1 
ATOM   16618 C CG2 . THR D 1 469 ? -24.865  -24.692 -5.189  1.00 75.03  ? 529 THR D CG2 1 
ATOM   16619 N N   . PHE D 1 470 ? -23.340  -20.280 -3.879  1.00 67.31  ? 530 PHE D N   1 
ATOM   16620 C CA  . PHE D 1 470 ? -22.665  -19.348 -2.926  1.00 59.76  ? 530 PHE D CA  1 
ATOM   16621 C C   . PHE D 1 470 ? -23.551  -19.189 -1.689  1.00 61.25  ? 530 PHE D C   1 
ATOM   16622 O O   . PHE D 1 470 ? -24.707  -18.741 -1.828  1.00 64.55  ? 530 PHE D O   1 
ATOM   16623 C CB  . PHE D 1 470 ? -22.383  -17.992 -3.581  1.00 51.95  ? 530 PHE D CB  1 
ATOM   16624 C CG  . PHE D 1 470 ? -21.397  -18.070 -4.719  1.00 58.55  ? 530 PHE D CG  1 
ATOM   16625 C CD1 . PHE D 1 470 ? -21.711  -18.759 -5.881  1.00 60.83  ? 530 PHE D CD1 1 
ATOM   16626 C CD2 . PHE D 1 470 ? -20.150  -17.466 -4.631  1.00 57.73  ? 530 PHE D CD2 1 
ATOM   16627 C CE1 . PHE D 1 470 ? -20.789  -18.869 -6.916  1.00 64.84  ? 530 PHE D CE1 1 
ATOM   16628 C CE2 . PHE D 1 470 ? -19.239  -17.559 -5.670  1.00 59.65  ? 530 PHE D CE2 1 
ATOM   16629 C CZ  . PHE D 1 470 ? -19.553  -18.267 -6.808  1.00 66.16  ? 530 PHE D CZ  1 
ATOM   16630 N N   . VAL D 1 471 ? -23.046  -19.590 -0.515  1.00 57.86  ? 531 VAL D N   1 
ATOM   16631 C CA  . VAL D 1 471 ? -23.729  -19.456 0.804   1.00 46.40  ? 531 VAL D CA  1 
ATOM   16632 C C   . VAL D 1 471 ? -23.151  -18.247 1.511   1.00 43.59  ? 531 VAL D C   1 
ATOM   16633 O O   . VAL D 1 471 ? -22.148  -18.375 2.180   1.00 47.46  ? 531 VAL D O   1 
ATOM   16634 C CB  . VAL D 1 471 ? -23.539  -20.722 1.644   1.00 40.94  ? 531 VAL D CB  1 
ATOM   16635 C CG1 . VAL D 1 471 ? -24.278  -20.593 2.957   1.00 49.23  ? 531 VAL D CG1 1 
ATOM   16636 C CG2 . VAL D 1 471 ? -23.999  -21.948 0.888   1.00 39.44  ? 531 VAL D CG2 1 
ATOM   16637 N N   . PRO D 1 472 ? -23.710  -17.032 1.369   1.00 51.77  ? 532 PRO D N   1 
ATOM   16638 C CA  . PRO D 1 472 ? -23.040  -15.830 1.881   1.00 53.00  ? 532 PRO D CA  1 
ATOM   16639 C C   . PRO D 1 472 ? -23.067  -15.896 3.402   1.00 59.10  ? 532 PRO D C   1 
ATOM   16640 O O   . PRO D 1 472 ? -24.072  -16.317 3.906   1.00 68.25  ? 532 PRO D O   1 
ATOM   16641 C CB  . PRO D 1 472 ? -23.865  -14.659 1.363   1.00 49.64  ? 532 PRO D CB  1 
ATOM   16642 C CG  . PRO D 1 472 ? -25.206  -15.283 1.081   1.00 53.95  ? 532 PRO D CG  1 
ATOM   16643 C CD  . PRO D 1 472 ? -25.001  -16.745 0.740   1.00 49.97  ? 532 PRO D CD  1 
ATOM   16644 N N   . GLY D 1 473 ? -21.961  -15.582 4.080   1.00 61.65  ? 533 GLY D N   1 
ATOM   16645 C CA  . GLY D 1 473 ? -21.931  -15.665 5.556   1.00 57.70  ? 533 GLY D CA  1 
ATOM   16646 C C   . GLY D 1 473 ? -22.691  -14.510 6.175   1.00 52.79  ? 533 GLY D C   1 
ATOM   16647 O O   . GLY D 1 473 ? -22.806  -13.457 5.465   1.00 47.50  ? 533 GLY D O   1 
ATOM   16648 N N   . GLN D 1 474 ? -23.176  -14.672 7.423   1.00 46.25  ? 534 GLN D N   1 
ATOM   16649 C CA  . GLN D 1 474 ? -23.846  -13.568 8.159   1.00 52.75  ? 534 GLN D CA  1 
ATOM   16650 C C   . GLN D 1 474 ? -22.869  -12.897 9.152   1.00 55.17  ? 534 GLN D C   1 
ATOM   16651 O O   . GLN D 1 474 ? -22.619  -13.443 10.262  1.00 58.28  ? 534 GLN D O   1 
ATOM   16652 C CB  . GLN D 1 474 ? -25.135  -14.036 8.828   1.00 56.14  ? 534 GLN D CB  1 
ATOM   16653 C CG  . GLN D 1 474 ? -26.170  -12.915 8.963   1.00 51.16  ? 534 GLN D CG  1 
ATOM   16654 C CD  . GLN D 1 474 ? -27.418  -13.364 9.670   1.00 49.75  ? 534 GLN D CD  1 
ATOM   16655 O OE1 . GLN D 1 474 ? -27.793  -14.547 9.609   1.00 56.80  ? 534 GLN D OE1 1 
ATOM   16656 N NE2 . GLN D 1 474 ? -28.093  -12.402 10.290  1.00 45.93  ? 534 GLN D NE2 1 
ATOM   16657 N N   . SER D 1 475 ? -22.368  -11.728 8.757   1.00 43.79  ? 535 SER D N   1 
ATOM   16658 C CA  . SER D 1 475 ? -21.465  -10.900 9.561   1.00 46.55  ? 535 SER D CA  1 
ATOM   16659 C C   . SER D 1 475 ? -22.329  -10.017 10.455  1.00 53.61  ? 535 SER D C   1 
ATOM   16660 O O   . SER D 1 475 ? -22.462  -8.815  10.152  1.00 56.44  ? 535 SER D O   1 
ATOM   16661 C CB  . SER D 1 475 ? -20.584  -10.128 8.667   1.00 53.57  ? 535 SER D CB  1 
ATOM   16662 O OG  . SER D 1 475 ? -19.902  -9.124  9.392   1.00 57.25  ? 535 SER D OG  1 
ATOM   16663 N N   . ASN D 1 476 ? -22.909  -10.634 11.494  1.00 58.70  ? 536 ASN D N   1 
ATOM   16664 C CA  . ASN D 1 476 ? -23.818  -10.012 12.497  1.00 55.83  ? 536 ASN D CA  1 
ATOM   16665 C C   . ASN D 1 476 ? -23.278  -10.289 13.911  1.00 57.50  ? 536 ASN D C   1 
ATOM   16666 O O   . ASN D 1 476 ? -22.846  -11.442 14.175  1.00 56.28  ? 536 ASN D O   1 
ATOM   16667 C CB  . ASN D 1 476 ? -25.253  -10.538 12.342  1.00 56.61  ? 536 ASN D CB  1 
ATOM   16668 C CG  . ASN D 1 476 ? -26.287  -9.761  13.134  1.00 56.63  ? 536 ASN D CG  1 
ATOM   16669 O OD1 . ASN D 1 476 ? -26.358  -9.870  14.360  1.00 57.41  ? 536 ASN D OD1 1 
ATOM   16670 N ND2 . ASN D 1 476 ? -27.091  -8.966  12.442  1.00 57.82  ? 536 ASN D ND2 1 
ATOM   16671 N N   . ASN D 1 477 ? -23.342  -9.297  14.808  1.00 54.85  ? 537 ASN D N   1 
ATOM   16672 C CA  . ASN D 1 477 ? -22.631  -9.355  16.113  1.00 55.23  ? 537 ASN D CA  1 
ATOM   16673 C C   . ASN D 1 477 ? -23.211  -10.485 16.986  1.00 50.06  ? 537 ASN D C   1 
ATOM   16674 O O   . ASN D 1 477 ? -22.629  -10.758 18.049  1.00 44.51  ? 537 ASN D O   1 
ATOM   16675 C CB  . ASN D 1 477 ? -22.582  -7.977  16.796  1.00 59.18  ? 537 ASN D CB  1 
ATOM   16676 C CG  . ASN D 1 477 ? -23.945  -7.365  16.947  1.00 54.96  ? 537 ASN D CG  1 
ATOM   16677 O OD1 . ASN D 1 477 ? -24.923  -8.070  17.189  1.00 64.13  ? 537 ASN D OD1 1 
ATOM   16678 N ND2 . ASN D 1 477 ? -24.008  -6.064  16.791  1.00 61.59  ? 537 ASN D ND2 1 
ATOM   16679 N N   . ALA D 1 478 ? -24.294  -11.130 16.561  1.00 50.15  ? 538 ALA D N   1 
ATOM   16680 C CA  . ALA D 1 478 ? -24.931  -12.296 17.228  1.00 51.72  ? 538 ALA D CA  1 
ATOM   16681 C C   . ALA D 1 478 ? -23.993  -13.509 17.298  1.00 54.03  ? 538 ALA D C   1 
ATOM   16682 O O   . ALA D 1 478 ? -24.270  -14.417 18.088  1.00 47.85  ? 538 ALA D O   1 
ATOM   16683 C CB  . ALA D 1 478 ? -26.179  -12.671 16.484  1.00 56.79  ? 538 ALA D CB  1 
ATOM   16684 N N   . TYR D 1 479 ? -22.960  -13.567 16.465  1.00 49.89  ? 539 TYR D N   1 
ATOM   16685 C CA  . TYR D 1 479 ? -21.896  -14.608 16.510  1.00 50.35  ? 539 TYR D CA  1 
ATOM   16686 C C   . TYR D 1 479 ? -20.913  -14.359 17.681  1.00 50.30  ? 539 TYR D C   1 
ATOM   16687 O O   . TYR D 1 479 ? -20.259  -15.319 18.165  1.00 42.10  ? 539 TYR D O   1 
ATOM   16688 C CB  . TYR D 1 479 ? -21.168  -14.596 15.161  1.00 56.58  ? 539 TYR D CB  1 
ATOM   16689 C CG  . TYR D 1 479 ? -21.672  -15.548 14.098  1.00 57.69  ? 539 TYR D CG  1 
ATOM   16690 C CD1 . TYR D 1 479 ? -21.494  -16.912 14.278  1.00 57.08  ? 539 TYR D CD1 1 
ATOM   16691 C CD2 . TYR D 1 479 ? -22.251  -15.118 12.905  1.00 50.50  ? 539 TYR D CD2 1 
ATOM   16692 C CE1 . TYR D 1 479 ? -21.886  -17.833 13.321  1.00 54.03  ? 539 TYR D CE1 1 
ATOM   16693 C CE2 . TYR D 1 479 ? -22.646  -16.035 11.938  1.00 55.27  ? 539 TYR D CE2 1 
ATOM   16694 C CZ  . TYR D 1 479 ? -22.464  -17.400 12.147  1.00 54.24  ? 539 TYR D CZ  1 
ATOM   16695 O OH  . TYR D 1 479 ? -22.860  -18.361 11.261  1.00 50.37  ? 539 TYR D OH  1 
ATOM   16696 N N   . ILE D 1 480 ? -20.801  -13.096 18.133  1.00 59.06  ? 540 ILE D N   1 
ATOM   16697 C CA  . ILE D 1 480 ? -19.752  -12.580 19.075  1.00 64.30  ? 540 ILE D CA  1 
ATOM   16698 C C   . ILE D 1 480 ? -20.361  -12.407 20.484  1.00 71.12  ? 540 ILE D C   1 
ATOM   16699 O O   . ILE D 1 480 ? -19.811  -13.032 21.405  1.00 77.91  ? 540 ILE D O   1 
ATOM   16700 C CB  . ILE D 1 480 ? -19.099  -11.268 18.557  1.00 60.73  ? 540 ILE D CB  1 
ATOM   16701 C CG1 . ILE D 1 480 ? -18.206  -11.487 17.333  1.00 62.70  ? 540 ILE D CG1 1 
ATOM   16702 C CG2 . ILE D 1 480 ? -18.328  -10.547 19.652  1.00 60.61  ? 540 ILE D CG2 1 
ATOM   16703 C CD1 . ILE D 1 480 ? -16.934  -12.269 17.578  1.00 59.05  ? 540 ILE D CD1 1 
ATOM   16704 N N   . PHE D 1 481 ? -21.414  -11.589 20.670  1.00 61.75  ? 541 PHE D N   1 
ATOM   16705 C CA  . PHE D 1 481 ? -21.831  -11.082 22.011  1.00 52.95  ? 541 PHE D CA  1 
ATOM   16706 C C   . PHE D 1 481 ? -22.305  -12.238 22.885  1.00 39.13  ? 541 PHE D C   1 
ATOM   16707 O O   . PHE D 1 481 ? -22.020  -12.207 24.066  1.00 43.12  ? 541 PHE D O   1 
ATOM   16708 C CB  . PHE D 1 481 ? -22.798  -9.885  21.931  1.00 53.53  ? 541 PHE D CB  1 
ATOM   16709 C CG  . PHE D 1 481 ? -24.213  -10.199 21.501  1.00 50.90  ? 541 PHE D CG  1 
ATOM   16710 C CD1 . PHE D 1 481 ? -25.055  -10.953 22.297  1.00 53.33  ? 541 PHE D CD1 1 
ATOM   16711 C CD2 . PHE D 1 481 ? -24.699  -9.786  20.276  1.00 47.24  ? 541 PHE D CD2 1 
ATOM   16712 C CE1 . PHE D 1 481 ? -26.341  -11.279 21.886  1.00 50.27  ? 541 PHE D CE1 1 
ATOM   16713 C CE2 . PHE D 1 481 ? -25.991  -10.104 19.871  1.00 49.81  ? 541 PHE D CE2 1 
ATOM   16714 C CZ  . PHE D 1 481 ? -26.819  -10.844 20.680  1.00 46.13  ? 541 PHE D CZ  1 
ATOM   16715 N N   . PRO D 1 482 ? -23.007  -13.283 22.400  1.00 33.04  ? 542 PRO D N   1 
ATOM   16716 C CA  . PRO D 1 482 ? -23.353  -14.436 23.236  1.00 36.52  ? 542 PRO D CA  1 
ATOM   16717 C C   . PRO D 1 482 ? -22.133  -15.088 23.888  1.00 38.69  ? 542 PRO D C   1 
ATOM   16718 O O   . PRO D 1 482 ? -22.188  -15.239 25.068  1.00 43.42  ? 542 PRO D O   1 
ATOM   16719 C CB  . PRO D 1 482 ? -24.027  -15.447 22.307  1.00 35.64  ? 542 PRO D CB  1 
ATOM   16720 C CG  . PRO D 1 482 ? -24.623  -14.527 21.271  1.00 40.30  ? 542 PRO D CG  1 
ATOM   16721 C CD  . PRO D 1 482 ? -23.580  -13.430 21.068  1.00 38.36  ? 542 PRO D CD  1 
ATOM   16722 N N   . GLY D 1 483 ? -21.097  -15.430 23.118  1.00 37.71  ? 543 GLY D N   1 
ATOM   16723 C CA  . GLY D 1 483 ? -19.812  -15.913 23.666  1.00 40.34  ? 543 GLY D CA  1 
ATOM   16724 C C   . GLY D 1 483 ? -19.084  -14.875 24.532  1.00 41.86  ? 543 GLY D C   1 
ATOM   16725 O O   . GLY D 1 483 ? -18.550  -15.242 25.597  1.00 38.67  ? 543 GLY D O   1 
ATOM   16726 N N   . LEU D 1 484 ? -19.011  -13.614 24.096  1.00 48.58  ? 544 LEU D N   1 
ATOM   16727 C CA  . LEU D 1 484 ? -18.242  -12.539 24.790  1.00 46.29  ? 544 LEU D CA  1 
ATOM   16728 C C   . LEU D 1 484 ? -18.912  -12.243 26.126  1.00 52.63  ? 544 LEU D C   1 
ATOM   16729 O O   . LEU D 1 484 ? -18.197  -12.050 27.126  1.00 59.16  ? 544 LEU D O   1 
ATOM   16730 C CB  . LEU D 1 484 ? -18.170  -11.280 23.927  1.00 42.96  ? 544 LEU D CB  1 
ATOM   16731 C CG  . LEU D 1 484 ? -17.498  -10.077 24.586  1.00 44.28  ? 544 LEU D CG  1 
ATOM   16732 C CD1 . LEU D 1 484 ? -16.402  -9.507  23.705  1.00 46.71  ? 544 LEU D CD1 1 
ATOM   16733 C CD2 . LEU D 1 484 ? -18.533  -9.001  24.913  1.00 50.84  ? 544 LEU D CD2 1 
ATOM   16734 N N   . GLY D 1 485 ? -20.242  -12.202 26.154  1.00 61.01  ? 545 GLY D N   1 
ATOM   16735 C CA  . GLY D 1 485 ? -21.010  -11.989 27.401  1.00 55.99  ? 545 GLY D CA  1 
ATOM   16736 C C   . GLY D 1 485 ? -20.766  -13.114 28.390  1.00 54.04  ? 545 GLY D C   1 
ATOM   16737 O O   . GLY D 1 485 ? -20.343  -12.795 29.496  1.00 56.26  ? 545 GLY D O   1 
ATOM   16738 N N   . LEU D 1 486 ? -21.015  -14.376 27.982  1.00 51.44  ? 546 LEU D N   1 
ATOM   16739 C CA  . LEU D 1 486 ? -20.825  -15.613 28.788  1.00 44.97  ? 546 LEU D CA  1 
ATOM   16740 C C   . LEU D 1 486 ? -19.425  -15.577 29.374  1.00 49.42  ? 546 LEU D C   1 
ATOM   16741 O O   . LEU D 1 486 ? -19.268  -15.922 30.561  1.00 61.35  ? 546 LEU D O   1 
ATOM   16742 C CB  . LEU D 1 486 ? -20.981  -16.868 27.924  1.00 43.06  ? 546 LEU D CB  1 
ATOM   16743 C CG  . LEU D 1 486 ? -20.787  -18.195 28.662  1.00 47.17  ? 546 LEU D CG  1 
ATOM   16744 C CD1 . LEU D 1 486 ? -21.889  -18.389 29.686  1.00 55.61  ? 546 LEU D CD1 1 
ATOM   16745 C CD2 . LEU D 1 486 ? -20.766  -19.391 27.738  1.00 46.97  ? 546 LEU D CD2 1 
ATOM   16746 N N   . GLY D 1 487 ? -18.449  -15.156 28.574  1.00 45.93  ? 547 GLY D N   1 
ATOM   16747 C CA  . GLY D 1 487 ? -17.041  -15.045 29.004  1.00 52.01  ? 547 GLY D CA  1 
ATOM   16748 C C   . GLY D 1 487 ? -16.862  -14.050 30.137  1.00 53.96  ? 547 GLY D C   1 
ATOM   16749 O O   . GLY D 1 487 ? -16.273  -14.438 31.157  1.00 64.12  ? 547 GLY D O   1 
ATOM   16750 N N   . LEU D 1 488 ? -17.322  -12.808 29.965  1.00 47.35  ? 548 LEU D N   1 
ATOM   16751 C CA  . LEU D 1 488 ? -17.226  -11.761 31.002  1.00 48.06  ? 548 LEU D CA  1 
ATOM   16752 C C   . LEU D 1 488 ? -17.884  -12.284 32.298  1.00 53.88  ? 548 LEU D C   1 
ATOM   16753 O O   . LEU D 1 488 ? -17.366  -12.029 33.424  1.00 61.05  ? 548 LEU D O   1 
ATOM   16754 C CB  . LEU D 1 488 ? -17.889  -10.475 30.498  1.00 53.31  ? 548 LEU D CB  1 
ATOM   16755 C CG  . LEU D 1 488 ? -17.371  -9.903  29.178  1.00 55.71  ? 548 LEU D CG  1 
ATOM   16756 C CD1 . LEU D 1 488 ? -17.925  -8.520  28.896  1.00 52.37  ? 548 LEU D CD1 1 
ATOM   16757 C CD2 . LEU D 1 488 ? -15.854  -9.867  29.124  1.00 62.07  ? 548 LEU D CD2 1 
ATOM   16758 N N   . VAL D 1 489 ? -18.992  -13.005 32.180  1.00 54.83  ? 549 VAL D N   1 
ATOM   16759 C CA  . VAL D 1 489 ? -19.730  -13.556 33.351  1.00 58.88  ? 549 VAL D CA  1 
ATOM   16760 C C   . VAL D 1 489 ? -18.903  -14.689 33.977  1.00 55.63  ? 549 VAL D C   1 
ATOM   16761 O O   . VAL D 1 489 ? -18.483  -14.486 35.099  1.00 60.34  ? 549 VAL D O   1 
ATOM   16762 C CB  . VAL D 1 489 ? -21.163  -13.975 32.989  1.00 61.06  ? 549 VAL D CB  1 
ATOM   16763 C CG1 . VAL D 1 489 ? -21.835  -14.718 34.139  1.00 70.88  ? 549 VAL D CG1 1 
ATOM   16764 C CG2 . VAL D 1 489 ? -21.996  -12.767 32.569  1.00 63.98  ? 549 VAL D CG2 1 
ATOM   16765 N N   . ILE D 1 490 ? -18.615  -15.791 33.281  1.00 51.02  ? 550 ILE D N   1 
ATOM   16766 C CA  . ILE D 1 490 ? -18.048  -17.027 33.914  1.00 52.71  ? 550 ILE D CA  1 
ATOM   16767 C C   . ILE D 1 490 ? -16.643  -16.783 34.488  1.00 53.54  ? 550 ILE D C   1 
ATOM   16768 O O   . ILE D 1 490 ? -16.154  -17.671 35.201  1.00 49.63  ? 550 ILE D O   1 
ATOM   16769 C CB  . ILE D 1 490 ? -18.020  -18.218 32.943  1.00 57.43  ? 550 ILE D CB  1 
ATOM   16770 C CG1 . ILE D 1 490 ? -17.074  -17.980 31.765  1.00 64.88  ? 550 ILE D CG1 1 
ATOM   16771 C CG2 . ILE D 1 490 ? -19.421  -18.590 32.498  1.00 55.09  ? 550 ILE D CG2 1 
ATOM   16772 C CD1 . ILE D 1 490 ? -17.036  -19.105 30.773  1.00 73.02  ? 550 ILE D CD1 1 
ATOM   16773 N N   . SER D 1 491 ? -16.020  -15.648 34.169  1.00 55.39  ? 551 SER D N   1 
ATOM   16774 C CA  . SER D 1 491 ? -14.678  -15.213 34.640  1.00 48.87  ? 551 SER D CA  1 
ATOM   16775 C C   . SER D 1 491 ? -14.854  -14.157 35.730  1.00 47.19  ? 551 SER D C   1 
ATOM   16776 O O   . SER D 1 491 ? -13.900  -13.865 36.442  1.00 56.83  ? 551 SER D O   1 
ATOM   16777 C CB  . SER D 1 491 ? -13.843  -14.649 33.498  1.00 53.42  ? 551 SER D CB  1 
ATOM   16778 O OG  . SER D 1 491 ? -14.127  -13.256 33.251  1.00 55.83  ? 551 SER D OG  1 
ATOM   16779 N N   . GLY D 1 492 ? -16.015  -13.541 35.799  1.00 46.43  ? 552 GLY D N   1 
ATOM   16780 C CA  . GLY D 1 492 ? -16.247  -12.432 36.740  1.00 55.57  ? 552 GLY D CA  1 
ATOM   16781 C C   . GLY D 1 492 ? -15.473  -11.191 36.351  1.00 49.63  ? 552 GLY D C   1 
ATOM   16782 O O   . GLY D 1 492 ? -15.090  -10.433 37.261  1.00 50.89  ? 552 GLY D O   1 
ATOM   16783 N N   . ALA D 1 493 ? -15.264  -10.981 35.054  1.00 44.82  ? 553 ALA D N   1 
ATOM   16784 C CA  . ALA D 1 493 ? -14.577  -9.780  34.542  1.00 51.92  ? 553 ALA D CA  1 
ATOM   16785 C C   . ALA D 1 493 ? -15.298  -8.531  35.043  1.00 50.37  ? 553 ALA D C   1 
ATOM   16786 O O   . ALA D 1 493 ? -16.525  -8.562  35.116  1.00 49.32  ? 553 ALA D O   1 
ATOM   16787 C CB  . ALA D 1 493 ? -14.521  -9.815  33.049  1.00 53.96  ? 553 ALA D CB  1 
ATOM   16788 N N   . VAL D 1 494 ? -14.535  -7.490  35.383  1.00 47.51  ? 554 VAL D N   1 
ATOM   16789 C CA  . VAL D 1 494 ? -15.049  -6.205  35.941  1.00 57.60  ? 554 VAL D CA  1 
ATOM   16790 C C   . VAL D 1 494 ? -14.862  -5.084  34.917  1.00 61.08  ? 554 VAL D C   1 
ATOM   16791 O O   . VAL D 1 494 ? -15.283  -3.916  35.185  1.00 57.11  ? 554 VAL D O   1 
ATOM   16792 C CB  . VAL D 1 494 ? -14.319  -5.842  37.243  1.00 63.61  ? 554 VAL D CB  1 
ATOM   16793 C CG1 . VAL D 1 494 ? -14.466  -6.943  38.291  1.00 70.99  ? 554 VAL D CG1 1 
ATOM   16794 C CG2 . VAL D 1 494 ? -12.856  -5.489  37.002  1.00 60.82  ? 554 VAL D CG2 1 
ATOM   16795 N N   . ARG D 1 495 ? -14.199  -5.400  33.806  1.00 65.63  ? 555 ARG D N   1 
ATOM   16796 C CA  . ARG D 1 495 ? -13.888  -4.402  32.759  1.00 72.30  ? 555 ARG D CA  1 
ATOM   16797 C C   . ARG D 1 495 ? -13.929  -5.039  31.380  1.00 73.23  ? 555 ARG D C   1 
ATOM   16798 O O   . ARG D 1 495 ? -13.637  -6.263  31.300  1.00 72.61  ? 555 ARG D O   1 
ATOM   16799 C CB  . ARG D 1 495 ? -12.468  -3.899  32.964  1.00 84.84  ? 555 ARG D CB  1 
ATOM   16800 C CG  . ARG D 1 495 ? -12.256  -2.465  32.531  1.00 91.34  ? 555 ARG D CG  1 
ATOM   16801 C CD  . ARG D 1 495 ? -13.061  -1.674  33.532  1.00 113.66 ? 555 ARG D CD  1 
ATOM   16802 N NE  . ARG D 1 495 ? -12.300  -0.603  34.174  1.00 136.39 ? 555 ARG D NE  1 
ATOM   16803 C CZ  . ARG D 1 495 ? -12.465  -0.204  35.435  1.00 146.54 ? 555 ARG D CZ  1 
ATOM   16804 N NH1 . ARG D 1 495 ? -13.377  -0.776  36.212  1.00 137.86 ? 555 ARG D NH1 1 
ATOM   16805 N NH2 . ARG D 1 495 ? -11.696  0.762   35.915  1.00 149.50 ? 555 ARG D NH2 1 
ATOM   16806 N N   . VAL D 1 496 ? -14.222  -4.230  30.356  1.00 65.66  ? 556 VAL D N   1 
ATOM   16807 C CA  . VAL D 1 496 ? -13.977  -4.616  28.939  1.00 70.76  ? 556 VAL D CA  1 
ATOM   16808 C C   . VAL D 1 496 ? -12.642  -3.994  28.502  1.00 72.97  ? 556 VAL D C   1 
ATOM   16809 O O   . VAL D 1 496 ? -12.478  -2.754  28.693  1.00 74.60  ? 556 VAL D O   1 
ATOM   16810 C CB  . VAL D 1 496 ? -15.157  -4.228  28.036  1.00 67.82  ? 556 VAL D CB  1 
ATOM   16811 C CG1 . VAL D 1 496 ? -16.364  -5.119  28.331  1.00 58.35  ? 556 VAL D CG1 1 
ATOM   16812 C CG2 . VAL D 1 496 ? -15.466  -2.729  28.127  1.00 76.33  ? 556 VAL D CG2 1 
ATOM   16813 N N   . HIS D 1 497 ? -11.725  -4.817  27.965  1.00 62.79  ? 557 HIS D N   1 
ATOM   16814 C CA  . HIS D 1 497 ? -10.468  -4.341  27.339  1.00 67.83  ? 557 HIS D CA  1 
ATOM   16815 C C   . HIS D 1 497 ? -10.506  -4.693  25.851  1.00 61.20  ? 557 HIS D C   1 
ATOM   16816 O O   . HIS D 1 497 ? -10.837  -5.872  25.501  1.00 61.60  ? 557 HIS D O   1 
ATOM   16817 C CB  . HIS D 1 497 ? -9.206   -4.905  28.018  1.00 79.40  ? 557 HIS D CB  1 
ATOM   16818 C CG  . HIS D 1 497 ? -7.922   -4.183  27.705  1.00 82.75  ? 557 HIS D CG  1 
ATOM   16819 N ND1 . HIS D 1 497 ? -7.353   -3.273  28.562  1.00 95.15  ? 557 HIS D ND1 1 
ATOM   16820 C CD2 . HIS D 1 497 ? -7.119   -4.180  26.606  1.00 85.53  ? 557 HIS D CD2 1 
ATOM   16821 C CE1 . HIS D 1 497 ? -6.259   -2.756  28.027  1.00 97.86  ? 557 HIS D CE1 1 
ATOM   16822 N NE2 . HIS D 1 497 ? -6.084   -3.319  26.836  1.00 95.10  ? 557 HIS D NE2 1 
ATOM   16823 N N   . GLU D 1 498 ? -10.164  -3.703  25.013  1.00 56.53  ? 558 GLU D N   1 
ATOM   16824 C CA  . GLU D 1 498 ? -10.049  -3.868  23.550  1.00 56.12  ? 558 GLU D CA  1 
ATOM   16825 C C   . GLU D 1 498 ? -9.432   -5.243  23.270  1.00 48.17  ? 558 GLU D C   1 
ATOM   16826 O O   . GLU D 1 498 ? -9.892   -5.879  22.352  1.00 47.59  ? 558 GLU D O   1 
ATOM   16827 C CB  . GLU D 1 498 ? -9.307   -2.689  22.907  1.00 63.85  ? 558 GLU D CB  1 
ATOM   16828 C CG  . GLU D 1 498 ? -8.097   -2.179  23.654  1.00 72.93  ? 558 GLU D CG  1 
ATOM   16829 C CD  . GLU D 1 498 ? -8.382   -1.030  24.610  1.00 101.83 ? 558 GLU D CD  1 
ATOM   16830 O OE1 . GLU D 1 498 ? -9.015   -1.255  25.700  1.00 103.05 ? 558 GLU D OE1 1 
ATOM   16831 O OE2 . GLU D 1 498 ? -7.965   0.099   24.270  1.00 128.13 ? 558 GLU D OE2 1 
ATOM   16832 N N   . ASP D 1 499 ? -8.479   -5.716  24.062  1.00 44.48  ? 559 ASP D N   1 
ATOM   16833 C CA  . ASP D 1 499 ? -7.783   -7.012  23.830  1.00 53.34  ? 559 ASP D CA  1 
ATOM   16834 C C   . ASP D 1 499 ? -8.764   -8.198  23.878  1.00 54.10  ? 559 ASP D C   1 
ATOM   16835 O O   . ASP D 1 499 ? -8.422   -9.237  23.285  1.00 50.93  ? 559 ASP D O   1 
ATOM   16836 C CB  . ASP D 1 499 ? -6.620   -7.219  24.800  1.00 61.82  ? 559 ASP D CB  1 
ATOM   16837 C CG  . ASP D 1 499 ? -5.374   -6.369  24.507  1.00 66.70  ? 559 ASP D CG  1 
ATOM   16838 O OD1 . ASP D 1 499 ? -5.517   -5.224  23.989  1.00 69.27  ? 559 ASP D OD1 1 
ATOM   16839 O OD2 . ASP D 1 499 ? -4.255   -6.828  24.846  1.00 59.67  ? 559 ASP D OD2 1 
ATOM   16840 N N   . MET D 1 500 ? -9.939   -8.066  24.507  1.00 57.26  ? 560 MET D N   1 
ATOM   16841 C CA  . MET D 1 500 ? -10.964  -9.159  24.602  1.00 64.96  ? 560 MET D CA  1 
ATOM   16842 C C   . MET D 1 500 ? -11.785  -9.240  23.304  1.00 72.70  ? 560 MET D C   1 
ATOM   16843 O O   . MET D 1 500 ? -12.131  -10.367 22.855  1.00 76.79  ? 560 MET D O   1 
ATOM   16844 C CB  . MET D 1 500 ? -11.915  -8.939  25.785  1.00 63.91  ? 560 MET D CB  1 
ATOM   16845 C CG  . MET D 1 500 ? -11.200  -8.635  27.081  1.00 65.73  ? 560 MET D CG  1 
ATOM   16846 S SD  . MET D 1 500 ? -12.072  -9.123  28.532  1.00 65.32  ? 560 MET D SD  1 
ATOM   16847 C CE  . MET D 1 500 ? -12.596  -7.536  29.142  1.00 58.87  ? 560 MET D CE  1 
ATOM   16848 N N   . LEU D 1 501 ? -12.100  -8.083  22.722  1.00 67.66  ? 561 LEU D N   1 
ATOM   16849 C CA  . LEU D 1 501 ? -12.702  -8.002  21.364  1.00 59.57  ? 561 LEU D CA  1 
ATOM   16850 C C   . LEU D 1 501 ? -11.823  -8.787  20.393  1.00 55.72  ? 561 LEU D C   1 
ATOM   16851 O O   . LEU D 1 501 ? -12.388  -9.601  19.654  1.00 65.54  ? 561 LEU D O   1 
ATOM   16852 C CB  . LEU D 1 501 ? -12.857  -6.535  20.960  1.00 60.66  ? 561 LEU D CB  1 
ATOM   16853 C CG  . LEU D 1 501 ? -13.671  -5.736  21.989  1.00 67.45  ? 561 LEU D CG  1 
ATOM   16854 C CD1 . LEU D 1 501 ? -13.687  -4.243  21.697  1.00 63.75  ? 561 LEU D CD1 1 
ATOM   16855 C CD2 . LEU D 1 501 ? -15.088  -6.283  22.096  1.00 71.13  ? 561 LEU D CD2 1 
ATOM   16856 N N   . LEU D 1 502 ? -10.497  -8.620  20.461  1.00 57.58  ? 562 LEU D N   1 
ATOM   16857 C CA  . LEU D 1 502 ? -9.535   -9.289  19.526  1.00 52.97  ? 562 LEU D CA  1 
ATOM   16858 C C   . LEU D 1 502 ? -9.538   -10.790 19.821  1.00 53.82  ? 562 LEU D C   1 
ATOM   16859 O O   . LEU D 1 502 ? -9.575   -11.572 18.856  1.00 58.21  ? 562 LEU D O   1 
ATOM   16860 C CB  . LEU D 1 502 ? -8.107   -8.745  19.656  1.00 46.23  ? 562 LEU D CB  1 
ATOM   16861 C CG  . LEU D 1 502 ? -7.891   -7.225  19.589  1.00 43.65  ? 562 LEU D CG  1 
ATOM   16862 C CD1 . LEU D 1 502 ? -6.408   -6.919  19.476  1.00 44.82  ? 562 LEU D CD1 1 
ATOM   16863 C CD2 . LEU D 1 502 ? -8.593   -6.540  18.427  1.00 46.02  ? 562 LEU D CD2 1 
ATOM   16864 N N   . ALA D 1 503 ? -9.521   -11.160 21.111  1.00 51.14  ? 563 ALA D N   1 
ATOM   16865 C CA  . ALA D 1 503 ? -9.482   -12.563 21.591  1.00 49.44  ? 563 ALA D CA  1 
ATOM   16866 C C   . ALA D 1 503 ? -10.690  -13.308 21.021  1.00 51.87  ? 563 ALA D C   1 
ATOM   16867 O O   . ALA D 1 503 ? -10.532  -14.475 20.582  1.00 54.90  ? 563 ALA D O   1 
ATOM   16868 C CB  . ALA D 1 503 ? -9.460   -12.587 23.095  1.00 46.89  ? 563 ALA D CB  1 
ATOM   16869 N N   . ALA D 1 504 ? -11.833  -12.617 21.009  1.00 49.93  ? 564 ALA D N   1 
ATOM   16870 C CA  . ALA D 1 504 ? -13.122  -13.101 20.476  1.00 56.51  ? 564 ALA D CA  1 
ATOM   16871 C C   . ALA D 1 504 ? -13.000  -13.283 18.956  1.00 57.87  ? 564 ALA D C   1 
ATOM   16872 O O   . ALA D 1 504 ? -13.281  -14.394 18.422  1.00 49.46  ? 564 ALA D O   1 
ATOM   16873 C CB  . ALA D 1 504 ? -14.201  -12.106 20.832  1.00 56.11  ? 564 ALA D CB  1 
ATOM   16874 N N   . SER D 1 505 ? -12.599  -12.209 18.283  1.00 53.89  ? 565 SER D N   1 
ATOM   16875 C CA  . SER D 1 505 ? -12.441  -12.179 16.815  1.00 55.29  ? 565 SER D CA  1 
ATOM   16876 C C   . SER D 1 505 ? -11.604  -13.395 16.394  1.00 58.53  ? 565 SER D C   1 
ATOM   16877 O O   . SER D 1 505 ? -12.042  -14.154 15.511  1.00 53.39  ? 565 SER D O   1 
ATOM   16878 C CB  . SER D 1 505 ? -11.827  -10.875 16.383  1.00 56.58  ? 565 SER D CB  1 
ATOM   16879 O OG  . SER D 1 505 ? -12.499  -9.759  16.961  1.00 56.27  ? 565 SER D OG  1 
ATOM   16880 N N   . LYS D 1 506 ? -10.449  -13.583 17.034  1.00 64.68  ? 566 LYS D N   1 
ATOM   16881 C CA  . LYS D 1 506 ? -9.558   -14.742 16.784  1.00 69.96  ? 566 LYS D CA  1 
ATOM   16882 C C   . LYS D 1 506 ? -10.356  -16.043 16.968  1.00 61.28  ? 566 LYS D C   1 
ATOM   16883 O O   . LYS D 1 506 ? -10.286  -16.895 16.077  1.00 55.57  ? 566 LYS D O   1 
ATOM   16884 C CB  . LYS D 1 506 ? -8.304   -14.657 17.660  1.00 81.55  ? 566 LYS D CB  1 
ATOM   16885 C CG  . LYS D 1 506 ? -7.238   -13.691 17.135  1.00 79.52  ? 566 LYS D CG  1 
ATOM   16886 C CD  . LYS D 1 506 ? -6.044   -13.478 18.073  1.00 86.42  ? 566 LYS D CD  1 
ATOM   16887 C CE  . LYS D 1 506 ? -5.416   -12.095 17.947  1.00 89.78  ? 566 LYS D CE  1 
ATOM   16888 N NZ  . LYS D 1 506 ? -4.757   -11.878 16.633  1.00 83.72  ? 566 LYS D NZ  1 
ATOM   16889 N N   . ALA D 1 507 ? -11.096  -16.173 18.066  1.00 58.42  ? 567 ALA D N   1 
ATOM   16890 C CA  . ALA D 1 507 ? -11.758  -17.436 18.469  1.00 58.50  ? 567 ALA D CA  1 
ATOM   16891 C C   . ALA D 1 507 ? -12.777  -17.846 17.398  1.00 57.56  ? 567 ALA D C   1 
ATOM   16892 O O   . ALA D 1 507 ? -12.850  -19.062 17.063  1.00 60.40  ? 567 ALA D O   1 
ATOM   16893 C CB  . ALA D 1 507 ? -12.411  -17.275 19.825  1.00 60.12  ? 567 ALA D CB  1 
ATOM   16894 N N   . LEU D 1 508 ? -13.532  -16.860 16.898  1.00 51.08  ? 568 LEU D N   1 
ATOM   16895 C CA  . LEU D 1 508 ? -14.592  -17.070 15.888  1.00 51.86  ? 568 LEU D CA  1 
ATOM   16896 C C   . LEU D 1 508 ? -13.936  -17.500 14.577  1.00 53.20  ? 568 LEU D C   1 
ATOM   16897 O O   . LEU D 1 508 ? -14.342  -18.531 13.991  1.00 63.53  ? 568 LEU D O   1 
ATOM   16898 C CB  . LEU D 1 508 ? -15.386  -15.771 15.709  1.00 53.94  ? 568 LEU D CB  1 
ATOM   16899 C CG  . LEU D 1 508 ? -16.445  -15.814 14.606  1.00 55.09  ? 568 LEU D CG  1 
ATOM   16900 C CD1 . LEU D 1 508 ? -17.388  -17.019 14.770  1.00 51.71  ? 568 LEU D CD1 1 
ATOM   16901 C CD2 . LEU D 1 508 ? -17.222  -14.498 14.544  1.00 53.36  ? 568 LEU D CD2 1 
ATOM   16902 N N   . ALA D 1 509 ? -12.963  -16.708 14.145  1.00 49.68  ? 569 ALA D N   1 
ATOM   16903 C CA  . ALA D 1 509 ? -12.212  -16.899 12.895  1.00 50.86  ? 569 ALA D CA  1 
ATOM   16904 C C   . ALA D 1 509 ? -11.605  -18.311 12.904  1.00 48.52  ? 569 ALA D C   1 
ATOM   16905 O O   . ALA D 1 509 ? -11.594  -18.945 11.857  1.00 50.30  ? 569 ALA D O   1 
ATOM   16906 C CB  . ALA D 1 509 ? -11.177  -15.810 12.776  1.00 52.28  ? 569 ALA D CB  1 
ATOM   16907 N N   . ASP D 1 510 ? -11.168  -18.802 14.062  1.00 52.64  ? 570 ASP D N   1 
ATOM   16908 C CA  . ASP D 1 510 ? -10.447  -20.095 14.195  1.00 64.95  ? 570 ASP D CA  1 
ATOM   16909 C C   . ASP D 1 510 ? -11.450  -21.241 14.270  1.00 61.24  ? 570 ASP D C   1 
ATOM   16910 O O   . ASP D 1 510 ? -11.012  -22.385 14.338  1.00 63.88  ? 570 ASP D O   1 
ATOM   16911 C CB  . ASP D 1 510 ? -9.462   -20.082 15.372  1.00 87.91  ? 570 ASP D CB  1 
ATOM   16912 C CG  . ASP D 1 510 ? -8.085   -19.495 15.038  1.00 113.13 ? 570 ASP D CG  1 
ATOM   16913 O OD1 . ASP D 1 510 ? -7.991   -18.601 14.140  1.00 117.78 ? 570 ASP D OD1 1 
ATOM   16914 O OD2 . ASP D 1 510 ? -7.095   -19.962 15.654  1.00 121.47 ? 570 ASP D OD2 1 
ATOM   16915 N N   . GLN D 1 511 ? -12.745  -20.938 14.226  1.00 68.65  ? 571 GLN D N   1 
ATOM   16916 C CA  . GLN D 1 511 ? -13.832  -21.945 14.068  1.00 66.18  ? 571 GLN D CA  1 
ATOM   16917 C C   . GLN D 1 511 ? -14.205  -22.111 12.591  1.00 63.22  ? 571 GLN D C   1 
ATOM   16918 O O   . GLN D 1 511 ? -14.844  -23.147 12.283  1.00 57.91  ? 571 GLN D O   1 
ATOM   16919 C CB  . GLN D 1 511 ? -15.043  -21.539 14.900  1.00 62.42  ? 571 GLN D CB  1 
ATOM   16920 C CG  . GLN D 1 511 ? -14.781  -21.689 16.380  1.00 69.20  ? 571 GLN D CG  1 
ATOM   16921 C CD  . GLN D 1 511 ? -14.451  -23.121 16.743  1.00 78.54  ? 571 GLN D CD  1 
ATOM   16922 O OE1 . GLN D 1 511 ? -15.005  -24.095 16.217  1.00 77.79  ? 571 GLN D OE1 1 
ATOM   16923 N NE2 . GLN D 1 511 ? -13.529  -23.257 17.676  1.00 89.57  ? 571 GLN D NE2 1 
ATOM   16924 N N   . ALA D 1 512 ? -13.811  -21.149 11.737  1.00 65.75  ? 572 ALA D N   1 
ATOM   16925 C CA  . ALA D 1 512 ? -14.073  -21.126 10.271  1.00 62.22  ? 572 ALA D CA  1 
ATOM   16926 C C   . ALA D 1 512 ? -13.172  -22.140 9.563   1.00 56.06  ? 572 ALA D C   1 
ATOM   16927 O O   . ALA D 1 512 ? -11.988  -21.875 9.464   1.00 56.56  ? 572 ALA D O   1 
ATOM   16928 C CB  . ALA D 1 512 ? -13.865  -19.734 9.704   1.00 55.82  ? 572 ALA D CB  1 
ATOM   16929 N N   . THR D 1 513 ? -13.719  -23.267 9.133   1.00 56.00  ? 573 THR D N   1 
ATOM   16930 C CA  . THR D 1 513 ? -12.970  -24.360 8.477   1.00 68.40  ? 573 THR D CA  1 
ATOM   16931 C C   . THR D 1 513 ? -13.274  -24.318 6.980   1.00 76.85  ? 573 THR D C   1 
ATOM   16932 O O   . THR D 1 513 ? -13.987  -23.396 6.543   1.00 63.91  ? 573 THR D O   1 
ATOM   16933 C CB  . THR D 1 513 ? -13.335  -25.723 9.080   1.00 74.27  ? 573 THR D CB  1 
ATOM   16934 O OG1 . THR D 1 513 ? -14.480  -26.229 8.375   1.00 68.50  ? 573 THR D OG1 1 
ATOM   16935 C CG2 . THR D 1 513 ? -13.574  -25.642 10.573  1.00 70.82  ? 573 THR D CG2 1 
ATOM   16936 N N   . GLN D 1 514 ? -12.762  -25.307 6.243   1.00 96.20  ? 574 GLN D N   1 
ATOM   16937 C CA  . GLN D 1 514 ? -12.966  -25.452 4.780   1.00 99.23  ? 574 GLN D CA  1 
ATOM   16938 C C   . GLN D 1 514 ? -14.408  -25.880 4.507   1.00 95.29  ? 574 GLN D C   1 
ATOM   16939 O O   . GLN D 1 514 ? -14.897  -25.576 3.407   1.00 87.66  ? 574 GLN D O   1 
ATOM   16940 C CB  . GLN D 1 514 ? -11.953  -26.434 4.179   1.00 101.72 ? 574 GLN D CB  1 
ATOM   16941 C CG  . GLN D 1 514 ? -11.374  -26.003 2.831   1.00 99.23  ? 574 GLN D CG  1 
ATOM   16942 C CD  . GLN D 1 514 ? -10.695  -24.652 2.884   1.00 98.75  ? 574 GLN D CD  1 
ATOM   16943 O OE1 . GLN D 1 514 ? -10.131  -24.248 3.899   1.00 84.77  ? 574 GLN D OE1 1 
ATOM   16944 N NE2 . GLN D 1 514 ? -10.779  -23.908 1.794   1.00 91.53  ? 574 GLN D NE2 1 
ATOM   16945 N N   . ASP D 1 515 ? -15.048  -26.578 5.447   1.00 91.68  ? 575 ASP D N   1 
ATOM   16946 C CA  . ASP D 1 515 ? -16.432  -27.093 5.273   1.00 92.65  ? 575 ASP D CA  1 
ATOM   16947 C C   . ASP D 1 515 ? -17.313  -25.904 4.887   1.00 80.13  ? 575 ASP D C   1 
ATOM   16948 O O   . ASP D 1 515 ? -18.098  -26.050 3.942   1.00 72.07  ? 575 ASP D O   1 
ATOM   16949 C CB  . ASP D 1 515 ? -16.909  -27.851 6.516   1.00 102.83 ? 575 ASP D CB  1 
ATOM   16950 C CG  . ASP D 1 515 ? -15.952  -28.960 6.943   1.00 112.55 ? 575 ASP D CG  1 
ATOM   16951 O OD1 . ASP D 1 515 ? -14.793  -28.972 6.481   1.00 108.12 ? 575 ASP D OD1 1 
ATOM   16952 O OD2 . ASP D 1 515 ? -16.354  -29.785 7.759   1.00 130.87 ? 575 ASP D OD2 1 
ATOM   16953 N N   . ASN D 1 516 ? -17.137  -24.764 5.562   1.00 77.87  ? 576 ASN D N   1 
ATOM   16954 C CA  . ASN D 1 516 ? -17.961  -23.551 5.322   1.00 76.64  ? 576 ASN D CA  1 
ATOM   16955 C C   . ASN D 1 516 ? -17.297  -22.687 4.249   1.00 73.82  ? 576 ASN D C   1 
ATOM   16956 O O   . ASN D 1 516 ? -18.049  -22.054 3.480   1.00 71.49  ? 576 ASN D O   1 
ATOM   16957 C CB  . ASN D 1 516 ? -18.294  -22.783 6.601   1.00 79.10  ? 576 ASN D CB  1 
ATOM   16958 C CG  . ASN D 1 516 ? -17.092  -22.455 7.448   1.00 77.44  ? 576 ASN D CG  1 
ATOM   16959 O OD1 . ASN D 1 516 ? -16.618  -23.316 8.196   1.00 93.37  ? 576 ASN D OD1 1 
ATOM   16960 N ND2 . ASN D 1 516 ? -16.634  -21.210 7.363   1.00 72.55  ? 576 ASN D ND2 1 
ATOM   16961 N N   . PHE D 1 517 ? -15.963  -22.688 4.148   1.00 76.43  ? 577 PHE D N   1 
ATOM   16962 C CA  . PHE D 1 517 ? -15.228  -21.950 3.077   1.00 71.98  ? 577 PHE D CA  1 
ATOM   16963 C C   . PHE D 1 517 ? -15.546  -22.540 1.695   1.00 64.74  ? 577 PHE D C   1 
ATOM   16964 O O   . PHE D 1 517 ? -15.707  -21.735 0.777   1.00 63.09  ? 577 PHE D O   1 
ATOM   16965 C CB  . PHE D 1 517 ? -13.712  -21.983 3.281   1.00 74.20  ? 577 PHE D CB  1 
ATOM   16966 C CG  . PHE D 1 517 ? -13.167  -21.197 4.442   1.00 70.77  ? 577 PHE D CG  1 
ATOM   16967 C CD1 . PHE D 1 517 ? -13.865  -20.140 4.993   1.00 78.64  ? 577 PHE D CD1 1 
ATOM   16968 C CD2 . PHE D 1 517 ? -11.929  -21.506 4.975   1.00 71.38  ? 577 PHE D CD2 1 
ATOM   16969 C CE1 . PHE D 1 517 ? -13.345  -19.434 6.073   1.00 77.53  ? 577 PHE D CE1 1 
ATOM   16970 C CE2 . PHE D 1 517 ? -11.415  -20.794 6.049   1.00 68.86  ? 577 PHE D CE2 1 
ATOM   16971 C CZ  . PHE D 1 517 ? -12.119  -19.757 6.598   1.00 63.71  ? 577 PHE D CZ  1 
ATOM   16972 N N   . GLU D 1 518 ? -15.576  -23.875 1.548   1.00 64.73  ? 578 GLU D N   1 
ATOM   16973 C CA  . GLU D 1 518 ? -16.036  -24.605 0.330   1.00 67.54  ? 578 GLU D CA  1 
ATOM   16974 C C   . GLU D 1 518 ? -17.240  -23.869 -0.264  1.00 61.84  ? 578 GLU D C   1 
ATOM   16975 O O   . GLU D 1 518 ? -17.130  -23.500 -1.412  1.00 58.80  ? 578 GLU D O   1 
ATOM   16976 C CB  . GLU D 1 518 ? -16.400  -26.061 0.647   1.00 83.88  ? 578 GLU D CB  1 
ATOM   16977 C CG  . GLU D 1 518 ? -16.480  -26.991 -0.558  1.00 97.01  ? 578 GLU D CG  1 
ATOM   16978 C CD  . GLU D 1 518 ? -16.430  -28.482 -0.201  1.00 119.26 ? 578 GLU D CD  1 
ATOM   16979 O OE1 . GLU D 1 518 ? -16.713  -28.817 0.985   1.00 117.88 ? 578 GLU D OE1 1 
ATOM   16980 O OE2 . GLU D 1 518 ? -16.104  -29.318 -1.099  1.00 105.48 ? 578 GLU D OE2 1 
ATOM   16981 N N   . LYS D 1 519 ? -18.300  -23.618 0.512   1.00 66.63  ? 579 LYS D N   1 
ATOM   16982 C CA  . LYS D 1 519 ? -19.570  -23.007 0.039   1.00 69.79  ? 579 LYS D CA  1 
ATOM   16983 C C   . LYS D 1 519 ? -19.452  -21.469 -0.068  1.00 64.25  ? 579 LYS D C   1 
ATOM   16984 O O   . LYS D 1 519 ? -20.446  -20.841 -0.404  1.00 76.27  ? 579 LYS D O   1 
ATOM   16985 C CB  . LYS D 1 519 ? -20.736  -23.291 0.989   1.00 92.08  ? 579 LYS D CB  1 
ATOM   16986 C CG  . LYS D 1 519 ? -20.787  -24.585 1.799   1.00 102.96 ? 579 LYS D CG  1 
ATOM   16987 C CD  . LYS D 1 519 ? -21.451  -24.358 3.179   1.00 117.10 ? 579 LYS D CD  1 
ATOM   16988 C CE  . LYS D 1 519 ? -22.221  -25.531 3.758   1.00 115.73 ? 579 LYS D CE  1 
ATOM   16989 N NZ  . LYS D 1 519 ? -22.631  -25.248 5.155   1.00 118.39 ? 579 LYS D NZ  1 
ATOM   16990 N N   . GLY D 1 520 ? -18.306  -20.859 0.219   1.00 53.74  ? 580 GLY D N   1 
ATOM   16991 C CA  . GLY D 1 520 ? -18.093  -19.406 0.077   1.00 52.99  ? 580 GLY D CA  1 
ATOM   16992 C C   . GLY D 1 520 ? -18.475  -18.624 1.329   1.00 56.64  ? 580 GLY D C   1 
ATOM   16993 O O   . GLY D 1 520 ? -18.591  -17.394 1.197   1.00 55.83  ? 580 GLY D O   1 
ATOM   16994 N N   . SER D 1 521 ? -18.622  -19.284 2.491   1.00 63.04  ? 581 SER D N   1 
ATOM   16995 C CA  . SER D 1 521 ? -19.059  -18.680 3.787   1.00 65.35  ? 581 SER D CA  1 
ATOM   16996 C C   . SER D 1 521 ? -17.879  -18.488 4.744   1.00 65.08  ? 581 SER D C   1 
ATOM   16997 O O   . SER D 1 521 ? -17.244  -19.502 5.106   1.00 59.46  ? 581 SER D O   1 
ATOM   16998 C CB  . SER D 1 521 ? -20.100  -19.513 4.492   1.00 69.19  ? 581 SER D CB  1 
ATOM   16999 O OG  . SER D 1 521 ? -21.328  -19.464 3.805   1.00 92.91  ? 581 SER D OG  1 
ATOM   17000 N N   . ILE D 1 522 ? -17.682  -17.249 5.204   1.00 57.62  ? 582 ILE D N   1 
ATOM   17001 C CA  . ILE D 1 522 ? -16.583  -16.885 6.132   1.00 52.90  ? 582 ILE D CA  1 
ATOM   17002 C C   . ILE D 1 522 ? -16.832  -17.477 7.525   1.00 57.17  ? 582 ILE D C   1 
ATOM   17003 O O   . ILE D 1 522 ? -15.863  -17.590 8.288   1.00 63.07  ? 582 ILE D O   1 
ATOM   17004 C CB  . ILE D 1 522 ? -16.380  -15.363 6.158   1.00 53.73  ? 582 ILE D CB  1 
ATOM   17005 C CG1 . ILE D 1 522 ? -17.549  -14.618 6.796   1.00 58.25  ? 582 ILE D CG1 1 
ATOM   17006 C CG2 . ILE D 1 522 ? -16.093  -14.843 4.766   1.00 56.56  ? 582 ILE D CG2 1 
ATOM   17007 C CD1 . ILE D 1 522 ? -17.382  -13.096 6.699   1.00 61.34  ? 582 ILE D CD1 1 
ATOM   17008 N N   . PHE D 1 523 ? -18.065  -17.828 7.878   1.00 54.23  ? 583 PHE D N   1 
ATOM   17009 C CA  . PHE D 1 523 ? -18.404  -18.343 9.235   1.00 53.36  ? 583 PHE D CA  1 
ATOM   17010 C C   . PHE D 1 523 ? -19.059  -19.705 9.132   1.00 55.33  ? 583 PHE D C   1 
ATOM   17011 O O   . PHE D 1 523 ? -19.696  -20.017 8.138   1.00 62.59  ? 583 PHE D O   1 
ATOM   17012 C CB  . PHE D 1 523 ? -19.388  -17.428 9.948   1.00 54.04  ? 583 PHE D CB  1 
ATOM   17013 C CG  . PHE D 1 523 ? -18.879  -16.029 10.121  1.00 56.17  ? 583 PHE D CG  1 
ATOM   17014 C CD1 . PHE D 1 523 ? -17.722  -15.805 10.823  1.00 56.91  ? 583 PHE D CD1 1 
ATOM   17015 C CD2 . PHE D 1 523 ? -19.553  -14.942 9.586   1.00 60.23  ? 583 PHE D CD2 1 
ATOM   17016 C CE1 . PHE D 1 523 ? -17.264  -14.510 11.027  1.00 60.25  ? 583 PHE D CE1 1 
ATOM   17017 C CE2 . PHE D 1 523 ? -19.093  -13.652 9.781   1.00 61.52  ? 583 PHE D CE2 1 
ATOM   17018 C CZ  . PHE D 1 523 ? -17.949  -13.441 10.514  1.00 57.31  ? 583 PHE D CZ  1 
ATOM   17019 N N   . PRO D 1 524 ? -18.974  -20.542 10.176  1.00 58.02  ? 584 PRO D N   1 
ATOM   17020 C CA  . PRO D 1 524 ? -19.676  -21.816 10.169  1.00 61.78  ? 584 PRO D CA  1 
ATOM   17021 C C   . PRO D 1 524 ? -21.158  -21.546 10.404  1.00 56.56  ? 584 PRO D C   1 
ATOM   17022 O O   . PRO D 1 524 ? -21.542  -20.481 10.883  1.00 48.10  ? 584 PRO D O   1 
ATOM   17023 C CB  . PRO D 1 524 ? -19.032  -22.633 11.296  1.00 65.69  ? 584 PRO D CB  1 
ATOM   17024 C CG  . PRO D 1 524 ? -18.374  -21.599 12.200  1.00 64.77  ? 584 PRO D CG  1 
ATOM   17025 C CD  . PRO D 1 524 ? -18.220  -20.312 11.408  1.00 64.37  ? 584 PRO D CD  1 
ATOM   17026 N N   . PRO D 1 525 ? -22.029  -22.528 10.089  1.00 57.98  ? 585 PRO D N   1 
ATOM   17027 C CA  . PRO D 1 525 ? -23.466  -22.316 10.192  1.00 59.04  ? 585 PRO D CA  1 
ATOM   17028 C C   . PRO D 1 525 ? -23.855  -22.093 11.672  1.00 61.72  ? 585 PRO D C   1 
ATOM   17029 O O   . PRO D 1 525 ? -23.109  -22.456 12.520  1.00 64.52  ? 585 PRO D O   1 
ATOM   17030 C CB  . PRO D 1 525 ? -24.058  -23.606 9.573   1.00 57.24  ? 585 PRO D CB  1 
ATOM   17031 C CG  . PRO D 1 525 ? -22.911  -24.332 8.913   1.00 56.17  ? 585 PRO D CG  1 
ATOM   17032 C CD  . PRO D 1 525 ? -21.682  -23.908 9.693   1.00 56.19  ? 585 PRO D CD  1 
ATOM   17033 N N   . PHE D 1 526 ? -25.027  -21.522 11.950  1.00 62.27  ? 586 PHE D N   1 
ATOM   17034 C CA  . PHE D 1 526 ? -25.535  -21.242 13.322  1.00 51.41  ? 586 PHE D CA  1 
ATOM   17035 C C   . PHE D 1 526 ? -25.863  -22.539 14.056  1.00 57.97  ? 586 PHE D C   1 
ATOM   17036 O O   . PHE D 1 526 ? -25.919  -22.503 15.289  1.00 66.07  ? 586 PHE D O   1 
ATOM   17037 C CB  . PHE D 1 526 ? -26.781  -20.376 13.290  1.00 41.49  ? 586 PHE D CB  1 
ATOM   17038 C CG  . PHE D 1 526 ? -26.483  -18.916 13.320  1.00 40.86  ? 586 PHE D CG  1 
ATOM   17039 C CD1 . PHE D 1 526 ? -25.844  -18.361 14.407  1.00 43.70  ? 586 PHE D CD1 1 
ATOM   17040 C CD2 . PHE D 1 526 ? -26.856  -18.090 12.271  1.00 47.71  ? 586 PHE D CD2 1 
ATOM   17041 C CE1 . PHE D 1 526 ? -25.612  -16.991 14.462  1.00 50.66  ? 586 PHE D CE1 1 
ATOM   17042 C CE2 . PHE D 1 526 ? -26.615  -16.722 12.313  1.00 50.42  ? 586 PHE D CE2 1 
ATOM   17043 C CZ  . PHE D 1 526 ? -26.004  -16.169 13.419  1.00 52.79  ? 586 PHE D CZ  1 
ATOM   17044 N N   . THR D 1 527 ? -26.049  -23.647 13.337  1.00 57.30  ? 587 THR D N   1 
ATOM   17045 C CA  . THR D 1 527 ? -26.166  -25.007 13.936  1.00 59.44  ? 587 THR D CA  1 
ATOM   17046 C C   . THR D 1 527 ? -24.905  -25.411 14.745  1.00 66.22  ? 587 THR D C   1 
ATOM   17047 O O   . THR D 1 527 ? -24.897  -26.541 15.261  1.00 65.28  ? 587 THR D O   1 
ATOM   17048 C CB  . THR D 1 527 ? -26.380  -26.052 12.845  1.00 55.06  ? 587 THR D CB  1 
ATOM   17049 O OG1 . THR D 1 527 ? -25.292  -25.886 11.932  1.00 60.35  ? 587 THR D OG1 1 
ATOM   17050 C CG2 . THR D 1 527 ? -27.709  -25.915 12.158  1.00 53.77  ? 587 THR D CG2 1 
ATOM   17051 N N   . SER D 1 528 ? -23.876  -24.565 14.865  1.00 61.87  ? 588 SER D N   1 
ATOM   17052 C CA  . SER D 1 528 ? -22.647  -24.827 15.673  1.00 67.36  ? 588 SER D CA  1 
ATOM   17053 C C   . SER D 1 528 ? -22.456  -23.778 16.783  1.00 67.06  ? 588 SER D C   1 
ATOM   17054 O O   . SER D 1 528 ? -21.402  -23.845 17.464  1.00 78.68  ? 588 SER D O   1 
ATOM   17055 C CB  . SER D 1 528 ? -21.403  -24.867 14.778  1.00 69.40  ? 588 SER D CB  1 
ATOM   17056 O OG  . SER D 1 528 ? -21.629  -25.636 13.608  1.00 72.88  ? 588 SER D OG  1 
ATOM   17057 N N   . ILE D 1 529 ? -23.393  -22.828 16.924  1.00 61.09  ? 589 ILE D N   1 
ATOM   17058 C CA  . ILE D 1 529 ? -23.217  -21.578 17.724  1.00 54.50  ? 589 ILE D CA  1 
ATOM   17059 C C   . ILE D 1 529 ? -22.995  -21.931 19.203  1.00 63.33  ? 589 ILE D C   1 
ATOM   17060 O O   . ILE D 1 529 ? -22.441  -21.086 19.958  1.00 66.38  ? 589 ILE D O   1 
ATOM   17061 C CB  . ILE D 1 529 ? -24.413  -20.629 17.525  1.00 53.13  ? 589 ILE D CB  1 
ATOM   17062 C CG1 . ILE D 1 529 ? -24.165  -19.219 18.089  1.00 50.95  ? 589 ILE D CG1 1 
ATOM   17063 C CG2 . ILE D 1 529 ? -25.678  -21.236 18.109  1.00 53.51  ? 589 ILE D CG2 1 
ATOM   17064 C CD1 . ILE D 1 529 ? -23.040  -18.439 17.399  1.00 47.29  ? 589 ILE D CD1 1 
ATOM   17065 N N   . ARG D 1 530 ? -23.393  -23.130 19.632  1.00 72.56  ? 590 ARG D N   1 
ATOM   17066 C CA  . ARG D 1 530 ? -23.102  -23.618 21.002  1.00 77.80  ? 590 ARG D CA  1 
ATOM   17067 C C   . ARG D 1 530 ? -21.577  -23.810 21.136  1.00 72.49  ? 590 ARG D C   1 
ATOM   17068 O O   . ARG D 1 530 ? -20.958  -23.220 22.057  1.00 64.79  ? 590 ARG D O   1 
ATOM   17069 C CB  . ARG D 1 530 ? -23.882  -24.921 21.228  1.00 90.65  ? 590 ARG D CB  1 
ATOM   17070 C CG  . ARG D 1 530 ? -24.597  -25.014 22.567  1.00 98.57  ? 590 ARG D CG  1 
ATOM   17071 C CD  . ARG D 1 530 ? -25.628  -23.909 22.699  1.00 98.27  ? 590 ARG D CD  1 
ATOM   17072 N NE  . ARG D 1 530 ? -26.536  -24.133 23.821  1.00 91.64  ? 590 ARG D NE  1 
ATOM   17073 C CZ  . ARG D 1 530 ? -27.106  -23.164 24.506  1.00 72.61  ? 590 ARG D CZ  1 
ATOM   17074 N NH1 . ARG D 1 530 ? -26.878  -21.904 24.183  1.00 78.69  ? 590 ARG D NH1 1 
ATOM   17075 N NH2 . ARG D 1 530 ? -27.930  -23.413 25.492  1.00 65.60  ? 590 ARG D NH2 1 
ATOM   17076 N N   . LYS D 1 531 ? -20.986  -24.580 20.221  1.00 69.62  ? 591 LYS D N   1 
ATOM   17077 C CA  . LYS D 1 531 ? -19.517  -24.773 20.175  1.00 66.95  ? 591 LYS D CA  1 
ATOM   17078 C C   . LYS D 1 531 ? -18.830  -23.400 20.038  1.00 61.14  ? 591 LYS D C   1 
ATOM   17079 O O   . LYS D 1 531 ? -17.947  -23.115 20.849  1.00 63.90  ? 591 LYS D O   1 
ATOM   17080 C CB  . LYS D 1 531 ? -19.104  -25.766 19.082  1.00 72.25  ? 591 LYS D CB  1 
ATOM   17081 C CG  . LYS D 1 531 ? -17.752  -26.418 19.336  1.00 79.44  ? 591 LYS D CG  1 
ATOM   17082 C CD  . LYS D 1 531 ? -16.966  -26.842 18.068  1.00 93.94  ? 591 LYS D CD  1 
ATOM   17083 C CE  . LYS D 1 531 ? -15.512  -27.228 18.326  1.00 98.73  ? 591 LYS D CE  1 
ATOM   17084 N NZ  . LYS D 1 531 ? -15.247  -28.693 18.256  1.00 91.53  ? 591 LYS D NZ  1 
ATOM   17085 N N   . ILE D 1 532 ? -19.236  -22.549 19.096  1.00 52.97  ? 592 ILE D N   1 
ATOM   17086 C CA  . ILE D 1 532 ? -18.594  -21.212 18.857  1.00 53.34  ? 592 ILE D CA  1 
ATOM   17087 C C   . ILE D 1 532 ? -18.571  -20.345 20.116  1.00 50.38  ? 592 ILE D C   1 
ATOM   17088 O O   . ILE D 1 532 ? -17.525  -19.697 20.351  1.00 41.01  ? 592 ILE D O   1 
ATOM   17089 C CB  . ILE D 1 532 ? -19.284  -20.433 17.727  1.00 54.29  ? 592 ILE D CB  1 
ATOM   17090 C CG1 . ILE D 1 532 ? -19.025  -21.126 16.381  1.00 54.40  ? 592 ILE D CG1 1 
ATOM   17091 C CG2 . ILE D 1 532 ? -18.846  -18.959 17.740  1.00 47.75  ? 592 ILE D CG2 1 
ATOM   17092 C CD1 . ILE D 1 532 ? -20.119  -20.971 15.365  1.00 57.85  ? 592 ILE D CD1 1 
ATOM   17093 N N   . SER D 1 533 ? -19.698  -20.275 20.830  1.00 51.70  ? 593 SER D N   1 
ATOM   17094 C CA  . SER D 1 533 ? -19.869  -19.380 22.007  1.00 56.25  ? 593 SER D CA  1 
ATOM   17095 C C   . SER D 1 533 ? -18.923  -19.834 23.133  1.00 52.66  ? 593 SER D C   1 
ATOM   17096 O O   . SER D 1 533 ? -18.297  -18.933 23.765  1.00 43.76  ? 593 SER D O   1 
ATOM   17097 C CB  . SER D 1 533 ? -21.328  -19.280 22.451  1.00 55.43  ? 593 SER D CB  1 
ATOM   17098 O OG  . SER D 1 533 ? -22.014  -18.292 21.700  1.00 62.04  ? 593 SER D OG  1 
ATOM   17099 N N   . ALA D 1 534 ? -18.791  -21.161 23.342  1.00 44.40  ? 594 ALA D N   1 
ATOM   17100 C CA  . ALA D 1 534 ? -17.912  -21.765 24.377  1.00 44.80  ? 594 ALA D CA  1 
ATOM   17101 C C   . ALA D 1 534 ? -16.448  -21.385 24.092  1.00 48.38  ? 594 ALA D C   1 
ATOM   17102 O O   . ALA D 1 534 ? -15.766  -20.925 25.010  1.00 44.81  ? 594 ALA D O   1 
ATOM   17103 C CB  . ALA D 1 534 ? -18.074  -23.271 24.435  1.00 44.34  ? 594 ALA D CB  1 
ATOM   17104 N N   . HIS D 1 535 ? -15.989  -21.564 22.853  1.00 49.06  ? 595 HIS D N   1 
ATOM   17105 C CA  . HIS D 1 535 ? -14.623  -21.193 22.423  1.00 49.92  ? 595 HIS D CA  1 
ATOM   17106 C C   . HIS D 1 535 ? -14.432  -19.674 22.531  1.00 45.31  ? 595 HIS D C   1 
ATOM   17107 O O   . HIS D 1 535 ? -13.368  -19.276 22.974  1.00 49.03  ? 595 HIS D O   1 
ATOM   17108 C CB  . HIS D 1 535 ? -14.323  -21.740 21.027  1.00 59.43  ? 595 HIS D CB  1 
ATOM   17109 C CG  . HIS D 1 535 ? -14.051  -23.206 21.026  1.00 65.52  ? 595 HIS D CG  1 
ATOM   17110 N ND1 . HIS D 1 535 ? -12.837  -23.731 21.402  1.00 61.92  ? 595 HIS D ND1 1 
ATOM   17111 C CD2 . HIS D 1 535 ? -14.829  -24.254 20.688  1.00 68.40  ? 595 HIS D CD2 1 
ATOM   17112 C CE1 . HIS D 1 535 ? -12.871  -25.044 21.274  1.00 69.66  ? 595 HIS D CE1 1 
ATOM   17113 N NE2 . HIS D 1 535 ? -14.079  -25.388 20.844  1.00 76.17  ? 595 HIS D NE2 1 
ATOM   17114 N N   . ILE D 1 536 ? -15.411  -18.850 22.177  1.00 44.29  ? 596 ILE D N   1 
ATOM   17115 C CA  . ILE D 1 536 ? -15.261  -17.374 22.321  1.00 49.00  ? 596 ILE D CA  1 
ATOM   17116 C C   . ILE D 1 536 ? -15.217  -17.066 23.820  1.00 52.02  ? 596 ILE D C   1 
ATOM   17117 O O   . ILE D 1 536 ? -14.416  -16.223 24.245  1.00 49.82  ? 596 ILE D O   1 
ATOM   17118 C CB  . ILE D 1 536 ? -16.392  -16.600 21.602  1.00 51.55  ? 596 ILE D CB  1 
ATOM   17119 C CG1 . ILE D 1 536 ? -16.340  -16.822 20.085  1.00 43.80  ? 596 ILE D CG1 1 
ATOM   17120 C CG2 . ILE D 1 536 ? -16.382  -15.104 21.982  1.00 46.76  ? 596 ILE D CG2 1 
ATOM   17121 C CD1 . ILE D 1 536 ? -17.516  -16.254 19.345  1.00 45.62  ? 596 ILE D CD1 1 
ATOM   17122 N N   . ALA D 1 537 ? -16.077  -17.701 24.604  1.00 52.82  ? 597 ALA D N   1 
ATOM   17123 C CA  . ALA D 1 537 ? -16.136  -17.457 26.056  1.00 60.56  ? 597 ALA D CA  1 
ATOM   17124 C C   . ALA D 1 537 ? -14.754  -17.768 26.674  1.00 65.50  ? 597 ALA D C   1 
ATOM   17125 O O   . ALA D 1 537 ? -14.181  -16.888 27.360  1.00 60.85  ? 597 ALA D O   1 
ATOM   17126 C CB  . ALA D 1 537 ? -17.259  -18.273 26.653  1.00 60.65  ? 597 ALA D CB  1 
ATOM   17127 N N   . ALA D 1 538 ? -14.223  -18.969 26.420  1.00 68.24  ? 598 ALA D N   1 
ATOM   17128 C CA  . ALA D 1 538 ? -12.940  -19.478 26.965  1.00 65.01  ? 598 ALA D CA  1 
ATOM   17129 C C   . ALA D 1 538 ? -11.833  -18.472 26.615  1.00 63.80  ? 598 ALA D C   1 
ATOM   17130 O O   . ALA D 1 538 ? -11.043  -18.163 27.503  1.00 65.42  ? 598 ALA D O   1 
ATOM   17131 C CB  . ALA D 1 538 ? -12.646  -20.863 26.430  1.00 61.60  ? 598 ALA D CB  1 
ATOM   17132 N N   . ALA D 1 539 ? -11.803  -17.959 25.384  1.00 63.20  ? 599 ALA D N   1 
ATOM   17133 C CA  . ALA D 1 539 ? -10.821  -16.946 24.916  1.00 69.65  ? 599 ALA D CA  1 
ATOM   17134 C C   . ALA D 1 539 ? -10.993  -15.619 25.665  1.00 66.84  ? 599 ALA D C   1 
ATOM   17135 O O   . ALA D 1 539 ? -9.979   -15.076 26.120  1.00 70.30  ? 599 ALA D O   1 
ATOM   17136 C CB  . ALA D 1 539 ? -10.948  -16.719 23.430  1.00 76.45  ? 599 ALA D CB  1 
ATOM   17137 N N   . VAL D 1 540 ? -12.218  -15.093 25.767  1.00 64.53  ? 600 VAL D N   1 
ATOM   17138 C CA  . VAL D 1 540 ? -12.488  -13.752 26.378  1.00 60.33  ? 600 VAL D CA  1 
ATOM   17139 C C   . VAL D 1 540 ? -12.213  -13.822 27.888  1.00 59.54  ? 600 VAL D C   1 
ATOM   17140 O O   . VAL D 1 540 ? -11.871  -12.769 28.484  1.00 54.97  ? 600 VAL D O   1 
ATOM   17141 C CB  . VAL D 1 540 ? -13.919  -13.262 26.105  1.00 48.75  ? 600 VAL D CB  1 
ATOM   17142 C CG1 . VAL D 1 540 ? -14.220  -12.029 26.934  1.00 48.37  ? 600 VAL D CG1 1 
ATOM   17143 C CG2 . VAL D 1 540 ? -14.147  -12.987 24.633  1.00 41.42  ? 600 VAL D CG2 1 
ATOM   17144 N N   . ALA D 1 541 ? -12.396  -15.007 28.472  1.00 55.96  ? 601 ALA D N   1 
ATOM   17145 C CA  . ALA D 1 541 ? -12.127  -15.306 29.896  1.00 63.47  ? 601 ALA D CA  1 
ATOM   17146 C C   . ALA D 1 541 ? -10.616  -15.359 30.111  1.00 61.25  ? 601 ALA D C   1 
ATOM   17147 O O   . ALA D 1 541 ? -10.113  -14.673 31.038  1.00 53.04  ? 601 ALA D O   1 
ATOM   17148 C CB  . ALA D 1 541 ? -12.792  -16.608 30.291  1.00 66.09  ? 601 ALA D CB  1 
ATOM   17149 N N   . ALA D 1 542 ? -9.923   -16.135 29.270  1.00 64.44  ? 602 ALA D N   1 
ATOM   17150 C CA  . ALA D 1 542 ? -8.450   -16.302 29.282  1.00 59.10  ? 602 ALA D CA  1 
ATOM   17151 C C   . ALA D 1 542 ? -7.806   -14.912 29.242  1.00 60.17  ? 602 ALA D C   1 
ATOM   17152 O O   . ALA D 1 542 ? -6.924   -14.660 30.072  1.00 60.75  ? 602 ALA D O   1 
ATOM   17153 C CB  . ALA D 1 542 ? -8.003   -17.174 28.134  1.00 54.92  ? 602 ALA D CB  1 
ATOM   17154 N N   . LYS D 1 543 ? -8.287   -14.034 28.354  1.00 62.91  ? 603 LYS D N   1 
ATOM   17155 C CA  . LYS D 1 543 ? -7.772   -12.652 28.195  1.00 66.51  ? 603 LYS D CA  1 
ATOM   17156 C C   . LYS D 1 543 ? -8.073   -11.837 29.448  1.00 62.21  ? 603 LYS D C   1 
ATOM   17157 O O   . LYS D 1 543 ? -7.259   -10.974 29.800  1.00 56.12  ? 603 LYS D O   1 
ATOM   17158 C CB  . LYS D 1 543 ? -8.351   -11.934 26.973  1.00 78.23  ? 603 LYS D CB  1 
ATOM   17159 C CG  . LYS D 1 543 ? -7.538   -10.706 26.521  1.00 90.90  ? 603 LYS D CG  1 
ATOM   17160 C CD  . LYS D 1 543 ? -6.046   -11.005 26.192  1.00 100.26 ? 603 LYS D CD  1 
ATOM   17161 C CE  . LYS D 1 543 ? -5.843   -11.882 24.966  1.00 102.14 ? 603 LYS D CE  1 
ATOM   17162 N NZ  . LYS D 1 543 ? -4.724   -12.839 25.100  1.00 107.75 ? 603 LYS D NZ  1 
ATOM   17163 N N   . ALA D 1 544 ? -9.212   -12.103 30.082  1.00 65.71  ? 604 ALA D N   1 
ATOM   17164 C CA  . ALA D 1 544 ? -9.659   -11.397 31.302  1.00 69.21  ? 604 ALA D CA  1 
ATOM   17165 C C   . ALA D 1 544 ? -8.679   -11.715 32.442  1.00 66.97  ? 604 ALA D C   1 
ATOM   17166 O O   . ALA D 1 544 ? -8.261   -10.753 33.125  1.00 64.64  ? 604 ALA D O   1 
ATOM   17167 C CB  . ALA D 1 544 ? -11.091  -11.770 31.627  1.00 68.86  ? 604 ALA D CB  1 
ATOM   17168 N N   . TYR D 1 545 ? -8.327   -12.997 32.606  1.00 57.98  ? 605 TYR D N   1 
ATOM   17169 C CA  . TYR D 1 545 ? -7.343   -13.520 33.592  1.00 57.88  ? 605 TYR D CA  1 
ATOM   17170 C C   . TYR D 1 545 ? -5.949   -12.950 33.291  1.00 58.97  ? 605 TYR D C   1 
ATOM   17171 O O   . TYR D 1 545 ? -5.380   -12.330 34.188  1.00 50.80  ? 605 TYR D O   1 
ATOM   17172 C CB  . TYR D 1 545 ? -7.289   -15.051 33.553  1.00 59.67  ? 605 TYR D CB  1 
ATOM   17173 C CG  . TYR D 1 545 ? -8.465   -15.735 34.185  1.00 60.12  ? 605 TYR D CG  1 
ATOM   17174 C CD1 . TYR D 1 545 ? -8.843   -15.449 35.486  1.00 67.07  ? 605 TYR D CD1 1 
ATOM   17175 C CD2 . TYR D 1 545 ? -9.191   -16.682 33.496  1.00 65.11  ? 605 TYR D CD2 1 
ATOM   17176 C CE1 . TYR D 1 545 ? -9.923   -16.074 36.089  1.00 62.63  ? 605 TYR D CE1 1 
ATOM   17177 C CE2 . TYR D 1 545 ? -10.278  -17.317 34.081  1.00 69.73  ? 605 TYR D CE2 1 
ATOM   17178 C CZ  . TYR D 1 545 ? -10.647  -17.012 35.381  1.00 67.54  ? 605 TYR D CZ  1 
ATOM   17179 O OH  . TYR D 1 545 ? -11.716  -17.634 35.953  1.00 80.60  ? 605 TYR D OH  1 
ATOM   17180 N N   . GLU D 1 546 ? -5.430   -13.154 32.071  1.00 59.77  ? 606 GLU D N   1 
ATOM   17181 C CA  . GLU D 1 546 ? -4.153   -12.576 31.572  1.00 59.84  ? 606 GLU D CA  1 
ATOM   17182 C C   . GLU D 1 546 ? -4.101   -11.088 31.961  1.00 56.80  ? 606 GLU D C   1 
ATOM   17183 O O   . GLU D 1 546 ? -3.206   -10.707 32.683  1.00 59.48  ? 606 GLU D O   1 
ATOM   17184 C CB  . GLU D 1 546 ? -4.056   -12.820 30.063  1.00 70.42  ? 606 GLU D CB  1 
ATOM   17185 C CG  . GLU D 1 546 ? -2.706   -12.524 29.426  1.00 79.49  ? 606 GLU D CG  1 
ATOM   17186 C CD  . GLU D 1 546 ? -2.588   -12.838 27.933  1.00 80.69  ? 606 GLU D CD  1 
ATOM   17187 O OE1 . GLU D 1 546 ? -3.375   -13.670 27.402  1.00 88.56  ? 606 GLU D OE1 1 
ATOM   17188 O OE2 . GLU D 1 546 ? -1.717   -12.239 27.277  1.00 69.37  ? 606 GLU D OE2 1 
ATOM   17189 N N   . LEU D 1 547 ? -5.063   -10.266 31.560  1.00 58.34  ? 607 LEU D N   1 
ATOM   17190 C CA  . LEU D 1 547 ? -5.097   -8.820  31.925  1.00 61.20  ? 607 LEU D CA  1 
ATOM   17191 C C   . LEU D 1 547 ? -5.359   -8.602  33.422  1.00 59.51  ? 607 LEU D C   1 
ATOM   17192 O O   . LEU D 1 547 ? -5.408   -7.428  33.849  1.00 55.37  ? 607 LEU D O   1 
ATOM   17193 C CB  . LEU D 1 547 ? -6.183   -8.129  31.106  1.00 61.52  ? 607 LEU D CB  1 
ATOM   17194 C CG  . LEU D 1 547 ? -5.830   -7.891  29.635  1.00 65.08  ? 607 LEU D CG  1 
ATOM   17195 C CD1 . LEU D 1 547 ? -7.012   -7.311  28.891  1.00 68.65  ? 607 LEU D CD1 1 
ATOM   17196 C CD2 . LEU D 1 547 ? -4.631   -6.970  29.444  1.00 65.54  ? 607 LEU D CD2 1 
ATOM   17197 N N   . GLY D 1 548 ? -5.560   -9.672  34.189  1.00 59.87  ? 608 GLY D N   1 
ATOM   17198 C CA  . GLY D 1 548 ? -5.913   -9.621  35.624  1.00 64.22  ? 608 GLY D CA  1 
ATOM   17199 C C   . GLY D 1 548 ? -7.109   -8.727  35.898  1.00 74.81  ? 608 GLY D C   1 
ATOM   17200 O O   . GLY D 1 548 ? -6.976   -7.822  36.739  1.00 80.81  ? 608 GLY D O   1 
ATOM   17201 N N   . LEU D 1 549 ? -8.226   -8.940  35.189  1.00 78.64  ? 609 LEU D N   1 
ATOM   17202 C CA  . LEU D 1 549 ? -9.518   -8.231  35.414  1.00 71.60  ? 609 LEU D CA  1 
ATOM   17203 C C   . LEU D 1 549 ? -10.604  -9.232  35.829  1.00 64.35  ? 609 LEU D C   1 
ATOM   17204 O O   . LEU D 1 549 ? -11.715  -8.782  36.197  1.00 59.18  ? 609 LEU D O   1 
ATOM   17205 C CB  . LEU D 1 549 ? -9.927   -7.475  34.148  1.00 63.65  ? 609 LEU D CB  1 
ATOM   17206 C CG  . LEU D 1 549 ? -8.967   -6.388  33.664  1.00 61.77  ? 609 LEU D CG  1 
ATOM   17207 C CD1 . LEU D 1 549 ? -9.244   -6.032  32.216  1.00 62.68  ? 609 LEU D CD1 1 
ATOM   17208 C CD2 . LEU D 1 549 ? -8.999   -5.141  34.536  1.00 61.37  ? 609 LEU D CD2 1 
ATOM   17209 N N   . ALA D 1 550 ? -10.293  -10.532 35.807  1.00 64.08  ? 610 ALA D N   1 
ATOM   17210 C CA  . ALA D 1 550 ? -11.161  -11.643 36.266  1.00 68.99  ? 610 ALA D CA  1 
ATOM   17211 C C   . ALA D 1 550 ? -11.182  -11.661 37.794  1.00 76.46  ? 610 ALA D C   1 
ATOM   17212 O O   . ALA D 1 550 ? -10.158  -11.248 38.367  1.00 101.50 ? 610 ALA D O   1 
ATOM   17213 C CB  . ALA D 1 550 ? -10.650  -12.942 35.711  1.00 58.99  ? 610 ALA D CB  1 
ATOM   17214 N N   . THR D 1 551 ? -12.290  -12.112 38.409  1.00 76.70  ? 611 THR D N   1 
ATOM   17215 C CA  . THR D 1 551 ? -12.448  -12.277 39.890  1.00 61.60  ? 611 THR D CA  1 
ATOM   17216 C C   . THR D 1 551 ? -12.906  -13.694 40.244  1.00 50.64  ? 611 THR D C   1 
ATOM   17217 O O   . THR D 1 551 ? -13.047  -13.941 41.395  1.00 51.60  ? 611 THR D O   1 
ATOM   17218 C CB  . THR D 1 551 ? -13.433  -11.283 40.522  1.00 62.34  ? 611 THR D CB  1 
ATOM   17219 O OG1 . THR D 1 551 ? -14.755  -11.698 40.172  1.00 78.44  ? 611 THR D OG1 1 
ATOM   17220 C CG2 . THR D 1 551 ? -13.209  -9.844  40.106  1.00 59.98  ? 611 THR D CG2 1 
ATOM   17221 N N   . ARG D 1 552 ? -13.142  -14.585 39.290  1.00 61.26  ? 612 ARG D N   1 
ATOM   17222 C CA  . ARG D 1 552 ? -13.348  -16.033 39.569  1.00 77.35  ? 612 ARG D CA  1 
ATOM   17223 C C   . ARG D 1 552 ? -11.984  -16.717 39.579  1.00 77.00  ? 612 ARG D C   1 
ATOM   17224 O O   . ARG D 1 552 ? -11.662  -17.378 38.578  1.00 88.43  ? 612 ARG D O   1 
ATOM   17225 C CB  . ARG D 1 552 ? -14.241  -16.695 38.521  1.00 85.86  ? 612 ARG D CB  1 
ATOM   17226 C CG  . ARG D 1 552 ? -15.685  -16.229 38.555  1.00 113.34 ? 612 ARG D CG  1 
ATOM   17227 C CD  . ARG D 1 552 ? -16.513  -16.790 39.698  1.00 121.07 ? 612 ARG D CD  1 
ATOM   17228 N NE  . ARG D 1 552 ? -17.762  -17.415 39.248  1.00 123.61 ? 612 ARG D NE  1 
ATOM   17229 C CZ  . ARG D 1 552 ? -18.631  -18.024 40.047  1.00 132.96 ? 612 ARG D CZ  1 
ATOM   17230 N NH1 . ARG D 1 552 ? -19.716  -18.578 39.535  1.00 140.21 ? 612 ARG D NH1 1 
ATOM   17231 N NH2 . ARG D 1 552 ? -18.421  -18.084 41.351  1.00 134.97 ? 612 ARG D NH2 1 
ATOM   17232 N N   . LEU D 1 553 ? -11.189  -16.516 40.644  1.00 75.55  ? 613 LEU D N   1 
ATOM   17233 C CA  . LEU D 1 553 ? -9.828   -17.097 40.790  1.00 76.88  ? 613 LEU D CA  1 
ATOM   17234 C C   . LEU D 1 553 ? -9.943   -18.361 41.644  1.00 80.54  ? 613 LEU D C   1 
ATOM   17235 O O   . LEU D 1 553 ? -10.809  -18.439 42.499  1.00 77.25  ? 613 LEU D O   1 
ATOM   17236 C CB  . LEU D 1 553 ? -8.885   -16.052 41.402  1.00 78.30  ? 613 LEU D CB  1 
ATOM   17237 C CG  . LEU D 1 553 ? -8.975   -14.598 40.902  1.00 80.98  ? 613 LEU D CG  1 
ATOM   17238 C CD1 . LEU D 1 553 ? -7.920   -13.724 41.566  1.00 89.02  ? 613 LEU D CD1 1 
ATOM   17239 C CD2 . LEU D 1 553 ? -8.805   -14.455 39.397  1.00 85.59  ? 613 LEU D CD2 1 
ATOM   17240 N N   . PRO D 1 554 ? -9.140   -19.429 41.425  1.00 90.00  ? 614 PRO D N   1 
ATOM   17241 C CA  . PRO D 1 554 ? -8.208   -19.507 40.297  1.00 92.80  ? 614 PRO D CA  1 
ATOM   17242 C C   . PRO D 1 554 ? -8.962   -19.832 39.005  1.00 95.77  ? 614 PRO D C   1 
ATOM   17243 O O   . PRO D 1 554 ? -10.089  -20.327 39.067  1.00 95.34  ? 614 PRO D O   1 
ATOM   17244 C CB  . PRO D 1 554 ? -7.271   -20.657 40.696  1.00 87.45  ? 614 PRO D CB  1 
ATOM   17245 C CG  . PRO D 1 554 ? -8.152   -21.563 41.542  1.00 82.09  ? 614 PRO D CG  1 
ATOM   17246 C CD  . PRO D 1 554 ? -9.124   -20.647 42.254  1.00 80.23  ? 614 PRO D CD  1 
ATOM   17247 N N   . PRO D 1 555 ? -8.370   -19.578 37.811  1.00 83.45  ? 615 PRO D N   1 
ATOM   17248 C CA  . PRO D 1 555 ? -8.990   -19.958 36.546  1.00 75.49  ? 615 PRO D CA  1 
ATOM   17249 C C   . PRO D 1 555 ? -9.111   -21.472 36.455  1.00 66.77  ? 615 PRO D C   1 
ATOM   17250 O O   . PRO D 1 555 ? -8.275   -22.201 36.962  1.00 63.84  ? 615 PRO D O   1 
ATOM   17251 C CB  . PRO D 1 555 ? -8.056   -19.417 35.453  1.00 78.16  ? 615 PRO D CB  1 
ATOM   17252 C CG  . PRO D 1 555 ? -6.741   -19.157 36.152  1.00 82.78  ? 615 PRO D CG  1 
ATOM   17253 C CD  . PRO D 1 555 ? -7.059   -18.944 37.618  1.00 85.40  ? 615 PRO D CD  1 
ATOM   17254 N N   . PRO D 1 556 ? -10.190  -22.005 35.866  1.00 63.63  ? 616 PRO D N   1 
ATOM   17255 C CA  . PRO D 1 556 ? -10.311  -23.448 35.685  1.00 63.82  ? 616 PRO D CA  1 
ATOM   17256 C C   . PRO D 1 556 ? -9.181   -23.954 34.791  1.00 70.69  ? 616 PRO D C   1 
ATOM   17257 O O   . PRO D 1 556 ? -8.663   -23.154 34.044  1.00 66.08  ? 616 PRO D O   1 
ATOM   17258 C CB  . PRO D 1 556 ? -11.658  -23.633 34.988  1.00 63.01  ? 616 PRO D CB  1 
ATOM   17259 C CG  . PRO D 1 556 ? -12.415  -22.352 35.305  1.00 67.43  ? 616 PRO D CG  1 
ATOM   17260 C CD  . PRO D 1 556 ? -11.373  -21.260 35.437  1.00 61.36  ? 616 PRO D CD  1 
ATOM   17261 N N   . SER D 1 557 ? -8.841   -25.245 34.891  1.00 79.89  ? 617 SER D N   1 
ATOM   17262 C CA  . SER D 1 557 ? -7.845   -25.913 34.013  1.00 76.87  ? 617 SER D CA  1 
ATOM   17263 C C   . SER D 1 557 ? -8.305   -25.783 32.556  1.00 80.54  ? 617 SER D C   1 
ATOM   17264 O O   . SER D 1 557 ? -7.512   -25.243 31.773  1.00 87.30  ? 617 SER D O   1 
ATOM   17265 C CB  . SER D 1 557 ? -7.644   -27.356 34.392  1.00 83.13  ? 617 SER D CB  1 
ATOM   17266 O OG  . SER D 1 557 ? -8.820   -28.107 34.114  1.00 90.70  ? 617 SER D OG  1 
ATOM   17267 N N   . ASP D 1 558 ? -9.552   -26.189 32.238  1.00 80.54  ? 618 ASP D N   1 
ATOM   17268 C CA  . ASP D 1 558 ? -10.111  -26.361 30.859  1.00 70.53  ? 618 ASP D CA  1 
ATOM   17269 C C   . ASP D 1 558 ? -11.225  -25.329 30.601  1.00 66.04  ? 618 ASP D C   1 
ATOM   17270 O O   . ASP D 1 558 ? -12.392  -25.705 30.729  1.00 90.11  ? 618 ASP D O   1 
ATOM   17271 C CB  . ASP D 1 558 ? -10.619  -27.798 30.676  1.00 64.91  ? 618 ASP D CB  1 
ATOM   17272 C CG  . ASP D 1 558 ? -11.030  -28.161 29.258  1.00 74.31  ? 618 ASP D CG  1 
ATOM   17273 O OD1 . ASP D 1 558 ? -11.166  -27.224 28.398  1.00 83.77  ? 618 ASP D OD1 1 
ATOM   17274 O OD2 . ASP D 1 558 ? -11.209  -29.380 29.020  1.00 75.81  ? 618 ASP D OD2 1 
ATOM   17275 N N   . LEU D 1 559 ? -10.886  -24.099 30.206  1.00 60.12  ? 619 LEU D N   1 
ATOM   17276 C CA  . LEU D 1 559 ? -11.822  -22.938 30.126  1.00 58.77  ? 619 LEU D CA  1 
ATOM   17277 C C   . LEU D 1 559 ? -12.975  -23.202 29.143  1.00 61.25  ? 619 LEU D C   1 
ATOM   17278 O O   . LEU D 1 559 ? -14.028  -22.569 29.292  1.00 58.04  ? 619 LEU D O   1 
ATOM   17279 C CB  . LEU D 1 559 ? -11.027  -21.697 29.693  1.00 64.92  ? 619 LEU D CB  1 
ATOM   17280 C CG  . LEU D 1 559 ? -11.246  -20.437 30.521  1.00 70.70  ? 619 LEU D CG  1 
ATOM   17281 C CD1 . LEU D 1 559 ? -11.363  -20.785 31.985  1.00 71.39  ? 619 LEU D CD1 1 
ATOM   17282 C CD2 . LEU D 1 559 ? -10.123  -19.419 30.308  1.00 73.24  ? 619 LEU D CD2 1 
ATOM   17283 N N   . VAL D 1 560 ? -12.775  -24.052 28.135  1.00 70.26  ? 620 VAL D N   1 
ATOM   17284 C CA  . VAL D 1 560 ? -13.832  -24.389 27.135  1.00 73.55  ? 620 VAL D CA  1 
ATOM   17285 C C   . VAL D 1 560 ? -14.880  -25.314 27.782  1.00 76.36  ? 620 VAL D C   1 
ATOM   17286 O O   . VAL D 1 560 ? -16.089  -24.972 27.726  1.00 96.69  ? 620 VAL D O   1 
ATOM   17287 C CB  . VAL D 1 560 ? -13.211  -24.973 25.856  1.00 73.53  ? 620 VAL D CB  1 
ATOM   17288 C CG1 . VAL D 1 560 ? -14.215  -25.748 25.021  1.00 72.94  ? 620 VAL D CG1 1 
ATOM   17289 C CG2 . VAL D 1 560 ? -12.563  -23.879 25.028  1.00 71.59  ? 620 VAL D CG2 1 
ATOM   17290 N N   . LYS D 1 561 ? -14.465  -26.431 28.385  1.00 67.17  ? 621 LYS D N   1 
ATOM   17291 C CA  . LYS D 1 561 ? -15.402  -27.405 29.017  1.00 71.57  ? 621 LYS D CA  1 
ATOM   17292 C C   . LYS D 1 561 ? -16.144  -26.741 30.193  1.00 66.63  ? 621 LYS D C   1 
ATOM   17293 O O   . LYS D 1 561 ? -17.295  -27.121 30.463  1.00 64.81  ? 621 LYS D O   1 
ATOM   17294 C CB  . LYS D 1 561 ? -14.668  -28.691 29.407  1.00 81.84  ? 621 LYS D CB  1 
ATOM   17295 C CG  . LYS D 1 561 ? -14.675  -29.087 30.883  1.00 88.99  ? 621 LYS D CG  1 
ATOM   17296 C CD  . LYS D 1 561 ? -14.620  -30.590 31.075  1.00 94.59  ? 621 LYS D CD  1 
ATOM   17297 C CE  . LYS D 1 561 ? -15.762  -31.308 30.378  1.00 90.74  ? 621 LYS D CE  1 
ATOM   17298 N NZ  . LYS D 1 561 ? -15.779  -32.753 30.705  1.00 94.89  ? 621 LYS D NZ  1 
ATOM   17299 N N   . TYR D 1 562 ? -15.528  -25.790 30.887  1.00 60.52  ? 622 TYR D N   1 
ATOM   17300 C CA  . TYR D 1 562 ? -16.169  -25.029 31.996  1.00 64.08  ? 622 TYR D CA  1 
ATOM   17301 C C   . TYR D 1 562 ? -17.285  -24.154 31.406  1.00 66.50  ? 622 TYR D C   1 
ATOM   17302 O O   . TYR D 1 562 ? -18.427  -24.193 31.925  1.00 74.46  ? 622 TYR D O   1 
ATOM   17303 C CB  . TYR D 1 562 ? -15.130  -24.215 32.784  1.00 60.88  ? 622 TYR D CB  1 
ATOM   17304 C CG  . TYR D 1 562 ? -15.669  -23.213 33.777  1.00 58.90  ? 622 TYR D CG  1 
ATOM   17305 C CD1 . TYR D 1 562 ? -16.298  -23.609 34.956  1.00 60.06  ? 622 TYR D CD1 1 
ATOM   17306 C CD2 . TYR D 1 562 ? -15.533  -21.852 33.538  1.00 62.18  ? 622 TYR D CD2 1 
ATOM   17307 C CE1 . TYR D 1 562 ? -16.825  -22.677 35.841  1.00 64.99  ? 622 TYR D CE1 1 
ATOM   17308 C CE2 . TYR D 1 562 ? -16.026  -20.909 34.422  1.00 62.87  ? 622 TYR D CE2 1 
ATOM   17309 C CZ  . TYR D 1 562 ? -16.682  -21.317 35.571  1.00 70.42  ? 622 TYR D CZ  1 
ATOM   17310 O OH  . TYR D 1 562 ? -17.133  -20.306 36.382  1.00 69.79  ? 622 TYR D OH  1 
ATOM   17311 N N   . ALA D 1 563 ? -16.968  -23.393 30.355  1.00 62.02  ? 623 ALA D N   1 
ATOM   17312 C CA  . ALA D 1 563 ? -17.917  -22.503 29.663  1.00 61.25  ? 623 ALA D CA  1 
ATOM   17313 C C   . ALA D 1 563 ? -19.129  -23.322 29.195  1.00 66.86  ? 623 ALA D C   1 
ATOM   17314 O O   . ALA D 1 563 ? -20.255  -22.808 29.356  1.00 69.21  ? 623 ALA D O   1 
ATOM   17315 C CB  . ALA D 1 563 ? -17.234  -21.802 28.520  1.00 58.38  ? 623 ALA D CB  1 
ATOM   17316 N N   . GLU D 1 564 ? -18.921  -24.533 28.647  1.00 68.36  ? 624 GLU D N   1 
ATOM   17317 C CA  . GLU D 1 564 ? -20.024  -25.410 28.148  1.00 67.17  ? 624 GLU D CA  1 
ATOM   17318 C C   . GLU D 1 564 ? -20.861  -25.935 29.322  1.00 67.03  ? 624 GLU D C   1 
ATOM   17319 O O   . GLU D 1 564 ? -22.038  -26.202 29.113  1.00 76.20  ? 624 GLU D O   1 
ATOM   17320 C CB  . GLU D 1 564 ? -19.520  -26.638 27.399  1.00 66.74  ? 624 GLU D CB  1 
ATOM   17321 C CG  . GLU D 1 564 ? -18.875  -26.365 26.069  1.00 73.88  ? 624 GLU D CG  1 
ATOM   17322 C CD  . GLU D 1 564 ? -18.091  -27.568 25.565  1.00 73.91  ? 624 GLU D CD  1 
ATOM   17323 O OE1 . GLU D 1 564 ? -17.928  -28.554 26.332  1.00 66.21  ? 624 GLU D OE1 1 
ATOM   17324 O OE2 . GLU D 1 564 ? -17.640  -27.519 24.401  1.00 88.54  ? 624 GLU D OE2 1 
ATOM   17325 N N   . ASN D 1 565 ? -20.267  -26.114 30.504  1.00 65.05  ? 625 ASN D N   1 
ATOM   17326 C CA  . ASN D 1 565 ? -20.963  -26.631 31.710  1.00 64.64  ? 625 ASN D CA  1 
ATOM   17327 C C   . ASN D 1 565 ? -21.745  -25.506 32.382  1.00 63.22  ? 625 ASN D C   1 
ATOM   17328 O O   . ASN D 1 565 ? -22.684  -25.836 33.073  1.00 66.71  ? 625 ASN D O   1 
ATOM   17329 C CB  . ASN D 1 565 ? -20.003  -27.319 32.682  1.00 63.13  ? 625 ASN D CB  1 
ATOM   17330 C CG  . ASN D 1 565 ? -19.604  -28.698 32.206  1.00 60.52  ? 625 ASN D CG  1 
ATOM   17331 O OD1 . ASN D 1 565 ? -20.290  -29.296 31.388  1.00 61.20  ? 625 ASN D OD1 1 
ATOM   17332 N ND2 . ASN D 1 565 ? -18.494  -29.210 32.699  1.00 60.06  ? 625 ASN D ND2 1 
ATOM   17333 N N   . CYS D 1 566 ? -21.399  -24.238 32.161  1.00 65.19  ? 626 CYS D N   1 
ATOM   17334 C CA  . CYS D 1 566 ? -22.170  -23.063 32.669  1.00 60.66  ? 626 CYS D CA  1 
ATOM   17335 C C   . CYS D 1 566 ? -23.392  -22.762 31.795  1.00 57.41  ? 626 CYS D C   1 
ATOM   17336 O O   . CYS D 1 566 ? -24.063  -21.783 32.103  1.00 65.73  ? 626 CYS D O   1 
ATOM   17337 C CB  . CYS D 1 566 ? -21.344  -21.785 32.682  1.00 54.89  ? 626 CYS D CB  1 
ATOM   17338 S SG  . CYS D 1 566 ? -20.001  -21.814 33.888  1.00 65.88  ? 626 CYS D SG  1 
ATOM   17339 N N   . MET D 1 567 ? -23.632  -23.523 30.732  1.00 58.24  ? 627 MET D N   1 
ATOM   17340 C CA  . MET D 1 567 ? -24.574  -23.127 29.653  1.00 59.96  ? 627 MET D CA  1 
ATOM   17341 C C   . MET D 1 567 ? -25.963  -23.686 29.953  1.00 53.16  ? 627 MET D C   1 
ATOM   17342 O O   . MET D 1 567 ? -26.088  -24.911 30.168  1.00 52.88  ? 627 MET D O   1 
ATOM   17343 C CB  . MET D 1 567 ? -24.129  -23.588 28.260  1.00 62.06  ? 627 MET D CB  1 
ATOM   17344 C CG  . MET D 1 567 ? -23.258  -22.591 27.515  1.00 63.80  ? 627 MET D CG  1 
ATOM   17345 S SD  . MET D 1 567 ? -22.786  -23.293 25.895  1.00 68.47  ? 627 MET D SD  1 
ATOM   17346 C CE  . MET D 1 567 ? -22.155  -21.828 25.098  1.00 62.20  ? 627 MET D CE  1 
ATOM   17347 N N   . TYR D 1 568 ? -26.939  -22.783 29.982  1.00 53.28  ? 628 TYR D N   1 
ATOM   17348 C CA  . TYR D 1 568 ? -28.381  -23.066 30.178  1.00 56.76  ? 628 TYR D CA  1 
ATOM   17349 C C   . TYR D 1 568 ? -28.818  -24.152 29.202  1.00 52.48  ? 628 TYR D C   1 
ATOM   17350 O O   . TYR D 1 568 ? -28.450  -24.061 28.032  1.00 48.30  ? 628 TYR D O   1 
ATOM   17351 C CB  . TYR D 1 568 ? -29.204  -21.786 30.044  1.00 46.86  ? 628 TYR D CB  1 
ATOM   17352 C CG  . TYR D 1 568 ? -30.689  -22.022 29.956  1.00 47.54  ? 628 TYR D CG  1 
ATOM   17353 C CD1 . TYR D 1 568 ? -31.485  -22.134 31.086  1.00 46.05  ? 628 TYR D CD1 1 
ATOM   17354 C CD2 . TYR D 1 568 ? -31.308  -22.054 28.718  1.00 52.25  ? 628 TYR D CD2 1 
ATOM   17355 C CE1 . TYR D 1 568 ? -32.856  -22.305 30.988  1.00 47.35  ? 628 TYR D CE1 1 
ATOM   17356 C CE2 . TYR D 1 568 ? -32.682  -22.219 28.601  1.00 49.55  ? 628 TYR D CE2 1 
ATOM   17357 C CZ  . TYR D 1 568 ? -33.447  -22.387 29.737  1.00 47.92  ? 628 TYR D CZ  1 
ATOM   17358 O OH  . TYR D 1 568 ? -34.789  -22.534 29.624  1.00 53.56  ? 628 TYR D OH  1 
ATOM   17359 N N   . THR D 1 569 ? -29.529  -25.152 29.694  1.00 53.19  ? 629 THR D N   1 
ATOM   17360 C CA  . THR D 1 569 ? -30.192  -26.142 28.817  1.00 59.57  ? 629 THR D CA  1 
ATOM   17361 C C   . THR D 1 569 ? -31.702  -25.992 29.031  1.00 66.35  ? 629 THR D C   1 
ATOM   17362 O O   . THR D 1 569 ? -32.184  -25.889 30.150  1.00 67.13  ? 629 THR D O   1 
ATOM   17363 C CB  . THR D 1 569 ? -29.657  -27.556 29.055  1.00 57.83  ? 629 THR D CB  1 
ATOM   17364 O OG1 . THR D 1 569 ? -30.549  -28.410 28.344  1.00 55.60  ? 629 THR D OG1 1 
ATOM   17365 C CG2 . THR D 1 569 ? -29.604  -27.940 30.522  1.00 60.11  ? 629 THR D CG2 1 
ATOM   17366 N N   . PRO D 1 570 ? -32.505  -25.927 27.960  1.00 53.29  ? 630 PRO D N   1 
ATOM   17367 C CA  . PRO D 1 570 ? -33.943  -25.806 28.102  1.00 53.32  ? 630 PRO D CA  1 
ATOM   17368 C C   . PRO D 1 570 ? -34.706  -27.158 28.110  1.00 55.72  ? 630 PRO D C   1 
ATOM   17369 O O   . PRO D 1 570 ? -35.930  -27.132 28.042  1.00 49.62  ? 630 PRO D O   1 
ATOM   17370 C CB  . PRO D 1 570 ? -34.237  -24.965 26.858  1.00 54.79  ? 630 PRO D CB  1 
ATOM   17371 C CG  . PRO D 1 570 ? -33.275  -25.463 25.809  1.00 58.14  ? 630 PRO D CG  1 
ATOM   17372 C CD  . PRO D 1 570 ? -32.069  -25.976 26.566  1.00 58.52  ? 630 PRO D CD  1 
ATOM   17373 N N   . VAL D 1 571 ? -34.019  -28.298 28.241  1.00 44.79  ? 631 VAL D N   1 
ATOM   17374 C CA  . VAL D 1 571 ? -34.713  -29.601 28.453  1.00 43.53  ? 631 VAL D CA  1 
ATOM   17375 C C   . VAL D 1 571 ? -35.584  -29.480 29.716  1.00 45.03  ? 631 VAL D C   1 
ATOM   17376 O O   . VAL D 1 571 ? -35.152  -28.820 30.669  1.00 42.79  ? 631 VAL D O   1 
ATOM   17377 C CB  . VAL D 1 571 ? -33.697  -30.764 28.540  1.00 48.05  ? 631 VAL D CB  1 
ATOM   17378 C CG1 . VAL D 1 571 ? -34.273  -32.028 29.175  1.00 49.59  ? 631 VAL D CG1 1 
ATOM   17379 C CG2 . VAL D 1 571 ? -33.094  -31.087 27.184  1.00 47.77  ? 631 VAL D CG2 1 
ATOM   17380 N N   . TYR D 1 572 ? -36.776  -30.095 29.736  1.00 54.58  ? 632 TYR D N   1 
ATOM   17381 C CA  . TYR D 1 572 ? -37.757  -29.985 30.857  1.00 47.45  ? 632 TYR D CA  1 
ATOM   17382 C C   . TYR D 1 572 ? -37.177  -30.651 32.104  1.00 52.51  ? 632 TYR D C   1 
ATOM   17383 O O   . TYR D 1 572 ? -36.776  -31.817 32.031  1.00 57.27  ? 632 TYR D O   1 
ATOM   17384 C CB  . TYR D 1 572 ? -39.120  -30.610 30.516  1.00 43.33  ? 632 TYR D CB  1 
ATOM   17385 C CG  . TYR D 1 572 ? -40.073  -29.771 29.696  1.00 44.85  ? 632 TYR D CG  1 
ATOM   17386 C CD1 . TYR D 1 572 ? -40.161  -28.373 29.832  1.00 44.91  ? 632 TYR D CD1 1 
ATOM   17387 C CD2 . TYR D 1 572 ? -40.899  -30.382 28.763  1.00 43.44  ? 632 TYR D CD2 1 
ATOM   17388 C CE1 . TYR D 1 572 ? -41.050  -27.616 29.077  1.00 40.38  ? 632 TYR D CE1 1 
ATOM   17389 C CE2 . TYR D 1 572 ? -41.792  -29.639 28.003  1.00 44.28  ? 632 TYR D CE2 1 
ATOM   17390 C CZ  . TYR D 1 572 ? -41.875  -28.260 28.166  1.00 43.92  ? 632 TYR D CZ  1 
ATOM   17391 O OH  . TYR D 1 572 ? -42.763  -27.564 27.402  1.00 43.02  ? 632 TYR D OH  1 
ATOM   17392 N N   . ARG D 1 573 ? -37.174  -29.919 33.220  1.00 62.82  ? 633 ARG D N   1 
ATOM   17393 C CA  . ARG D 1 573 ? -36.917  -30.416 34.601  1.00 66.64  ? 633 ARG D CA  1 
ATOM   17394 C C   . ARG D 1 573 ? -38.132  -31.218 35.065  1.00 64.68  ? 633 ARG D C   1 
ATOM   17395 O O   . ARG D 1 573 ? -39.196  -30.930 34.585  1.00 56.13  ? 633 ARG D O   1 
ATOM   17396 C CB  . ARG D 1 573 ? -36.670  -29.246 35.563  1.00 65.87  ? 633 ARG D CB  1 
ATOM   17397 C CG  . ARG D 1 573 ? -35.278  -28.617 35.501  1.00 72.51  ? 633 ARG D CG  1 
ATOM   17398 C CD  . ARG D 1 573 ? -34.821  -27.781 36.721  1.00 78.10  ? 633 ARG D CD  1 
ATOM   17399 N NE  . ARG D 1 573 ? -35.742  -26.652 37.048  1.00 97.26  ? 633 ARG D NE  1 
ATOM   17400 C CZ  . ARG D 1 573 ? -35.419  -25.421 37.512  1.00 78.39  ? 633 ARG D CZ  1 
ATOM   17401 N NH1 . ARG D 1 573 ? -34.152  -25.098 37.713  1.00 82.86  ? 633 ARG D NH1 1 
ATOM   17402 N NH2 . ARG D 1 573 ? -36.364  -24.514 37.746  1.00 54.50  ? 633 ARG D NH2 1 
ATOM   17403 N N   . ASN D 1 574 ? -37.971  -32.191 35.960  1.00 77.25  ? 634 ASN D N   1 
ATOM   17404 C CA  . ASN D 1 574 ? -39.099  -32.991 36.528  1.00 82.25  ? 634 ASN D CA  1 
ATOM   17405 C C   . ASN D 1 574 ? -39.462  -32.441 37.918  1.00 76.26  ? 634 ASN D C   1 
ATOM   17406 O O   . ASN D 1 574 ? -38.556  -32.397 38.772  1.00 74.90  ? 634 ASN D O   1 
ATOM   17407 C CB  . ASN D 1 574 ? -38.792  -34.497 36.586  1.00 79.40  ? 634 ASN D CB  1 
ATOM   17408 C CG  . ASN D 1 574 ? -38.876  -35.206 35.252  1.00 78.83  ? 634 ASN D CG  1 
ATOM   17409 O OD1 . ASN D 1 574 ? -39.925  -35.231 34.592  1.00 71.48  ? 634 ASN D OD1 1 
ATOM   17410 N ND2 . ASN D 1 574 ? -37.790  -35.877 34.901  1.00 82.18  ? 634 ASN D ND2 1 
ATOM   17411 N N   . TYR D 1 575 ? -40.739  -32.149 38.153  1.00 74.13  ? 635 TYR D N   1 
ATOM   17412 C CA  . TYR D 1 575 ? -41.283  -31.469 39.356  1.00 82.17  ? 635 TYR D CA  1 
ATOM   17413 C C   . TYR D 1 575 ? -42.034  -32.412 40.318  1.00 85.02  ? 635 TYR D C   1 
ATOM   17414 O O   . TYR D 1 575 ? -42.643  -33.421 39.876  1.00 77.38  ? 635 TYR D O   1 
ATOM   17415 C CB  . TYR D 1 575 ? -42.227  -30.373 38.874  1.00 79.44  ? 635 TYR D CB  1 
ATOM   17416 C CG  . TYR D 1 575 ? -41.547  -29.268 38.107  1.00 68.05  ? 635 TYR D CG  1 
ATOM   17417 C CD1 . TYR D 1 575 ? -40.831  -28.306 38.782  1.00 63.83  ? 635 TYR D CD1 1 
ATOM   17418 C CD2 . TYR D 1 575 ? -41.712  -29.108 36.747  1.00 66.98  ? 635 TYR D CD2 1 
ATOM   17419 C CE1 . TYR D 1 575 ? -40.243  -27.245 38.121  1.00 65.95  ? 635 TYR D CE1 1 
ATOM   17420 C CE2 . TYR D 1 575 ? -41.123  -28.057 36.068  1.00 69.67  ? 635 TYR D CE2 1 
ATOM   17421 C CZ  . TYR D 1 575 ? -40.388  -27.119 36.761  1.00 65.85  ? 635 TYR D CZ  1 
ATOM   17422 O OH  . TYR D 1 575 ? -39.803  -26.056 36.153  1.00 76.13  ? 635 TYR D OH  1 
ATOM   17423 N N   . ARG D 1 576 ? -42.023  -32.029 41.605  1.00 97.06  ? 636 ARG D N   1 
ATOM   17424 C CA  . ARG D 1 576 ? -42.618  -32.791 42.736  1.00 105.16 ? 636 ARG D CA  1 
ATOM   17425 C C   . ARG D 1 576 ? -43.507  -31.874 43.595  1.00 95.97  ? 636 ARG D C   1 
ATOM   17426 O O   . ARG D 1 576 ? -44.586  -32.269 44.085  1.00 92.85  ? 636 ARG D O   1 
ATOM   17427 C CB  . ARG D 1 576 ? -41.494  -33.433 43.562  1.00 109.66 ? 636 ARG D CB  1 
ATOM   17428 C CG  . ARG D 1 576 ? -40.656  -32.472 44.401  1.00 100.51 ? 636 ARG D CG  1 
ATOM   17429 C CD  . ARG D 1 576 ? -39.899  -33.206 45.503  1.00 100.68 ? 636 ARG D CD  1 
ATOM   17430 N NE  . ARG D 1 576 ? -40.796  -33.744 46.534  1.00 105.48 ? 636 ARG D NE  1 
ATOM   17431 C CZ  . ARG D 1 576 ? -40.963  -33.259 47.773  1.00 97.04  ? 636 ARG D CZ  1 
ATOM   17432 N NH1 . ARG D 1 576 ? -40.255  -32.230 48.207  1.00 88.10  ? 636 ARG D NH1 1 
ATOM   17433 N NH2 . ARG D 1 576 ? -41.823  -33.837 48.598  1.00 90.32  ? 636 ARG D NH2 1 
HETATM 17434 C C   . PYR E 2 .   ? -71.270  -3.705  78.888  1.00 69.51  ? 701 PYR A C   1 
HETATM 17435 O O   . PYR E 2 .   ? -71.450  -3.555  80.094  1.00 56.41  ? 701 PYR A O   1 
HETATM 17436 O OXT . PYR E 2 .   ? -71.036  -2.732  78.179  1.00 61.13  ? 701 PYR A OXT 1 
HETATM 17437 C CA  . PYR E 2 .   ? -71.303  -4.935  78.311  1.00 86.82  ? 701 PYR A CA  1 
HETATM 17438 O O3  . PYR E 2 .   ? -70.918  -5.087  77.138  1.00 102.02 ? 701 PYR A O3  1 
HETATM 17439 C CB  . PYR E 2 .   ? -71.797  -6.193  78.972  1.00 80.16  ? 701 PYR A CB  1 
HETATM 17440 C C   . PYR F 2 .   ? -47.115  -14.903 73.798  1.00 93.04  ? 702 PYR A C   1 
HETATM 17441 O O   . PYR F 2 .   ? -46.207  -14.334 74.404  1.00 85.47  ? 702 PYR A O   1 
HETATM 17442 O OXT . PYR F 2 .   ? -47.733  -14.285 72.908  1.00 97.78  ? 702 PYR A OXT 1 
HETATM 17443 C CA  . PYR F 2 .   ? -47.434  -16.176 74.174  1.00 85.94  ? 702 PYR A CA  1 
HETATM 17444 O O3  . PYR F 2 .   ? -46.926  -16.644 75.186  1.00 94.47  ? 702 PYR A O3  1 
HETATM 17445 C CB  . PYR F 2 .   ? -48.388  -17.107 73.479  1.00 78.69  ? 702 PYR A CB  1 
HETATM 17446 C C   . PYR G 2 .   ? -22.821  -29.934 75.889  1.00 82.66  ? 701 PYR B C   1 
HETATM 17447 O O   . PYR G 2 .   ? -22.167  -30.570 76.730  1.00 89.42  ? 701 PYR B O   1 
HETATM 17448 O OXT . PYR G 2 .   ? -23.562  -30.438 75.051  1.00 82.40  ? 701 PYR B OXT 1 
HETATM 17449 C CA  . PYR G 2 .   ? -22.714  -28.677 75.871  1.00 73.07  ? 701 PYR B CA  1 
HETATM 17450 O O3  . PYR G 2 .   ? -22.813  -28.069 74.809  1.00 70.42  ? 701 PYR B O3  1 
HETATM 17451 C CB  . PYR G 2 .   ? -22.530  -27.932 77.158  1.00 67.56  ? 701 PYR B CB  1 
HETATM 17452 C C   . PYR H 2 .   ? -75.676  -28.247 16.740  1.00 83.03  ? 701 PYR C C   1 
HETATM 17453 O O   . PYR H 2 .   ? -75.381  -29.307 17.287  1.00 71.85  ? 701 PYR C O   1 
HETATM 17454 O OXT . PYR H 2 .   ? -75.816  -28.192 15.490  1.00 71.69  ? 701 PYR C OXT 1 
HETATM 17455 C CA  . PYR H 2 .   ? -75.855  -27.161 17.535  1.00 96.87  ? 701 PYR C CA  1 
HETATM 17456 O O3  . PYR H 2 .   ? -76.236  -27.260 18.722  1.00 95.82  ? 701 PYR C O3  1 
HETATM 17457 C CB  . PYR H 2 .   ? -75.559  -25.761 17.058  1.00 95.91  ? 701 PYR C CB  1 
HETATM 17458 C C   . PYR I 2 .   ? -51.975  -14.101 18.800  1.00 90.82  ? 702 PYR C C   1 
HETATM 17459 O O   . PYR I 2 .   ? -51.784  -13.453 19.841  1.00 89.91  ? 702 PYR C O   1 
HETATM 17460 O OXT . PYR I 2 .   ? -52.613  -13.581 17.883  1.00 99.23  ? 702 PYR C OXT 1 
HETATM 17461 C CA  . PYR I 2 .   ? -51.503  -15.372 18.646  1.00 79.75  ? 702 PYR C CA  1 
HETATM 17462 O O3  . PYR I 2 .   ? -51.876  -16.114 17.746  1.00 78.50  ? 702 PYR C O3  1 
HETATM 17463 C CB  . PYR I 2 .   ? -50.469  -15.982 19.536  1.00 77.06  ? 702 PYR C CB  1 
HETATM 17464 C C   . PYR J 2 .   ? -27.067  -2.541  13.407  1.00 83.95  ? 701 PYR D C   1 
HETATM 17465 O O   . PYR J 2 .   ? -26.406  -1.540  13.710  1.00 85.21  ? 701 PYR D O   1 
HETATM 17466 O OXT . PYR J 2 .   ? -27.433  -2.790  12.237  1.00 69.28  ? 701 PYR D OXT 1 
HETATM 17467 C CA  . PYR J 2 .   ? -27.418  -3.305  14.413  1.00 88.30  ? 701 PYR D CA  1 
HETATM 17468 O O3  . PYR J 2 .   ? -27.619  -2.743  15.505  1.00 84.03  ? 701 PYR D O3  1 
HETATM 17469 C CB  . PYR J 2 .   ? -27.552  -4.811  14.328  1.00 89.06  ? 701 PYR D CB  1 
HETATM 17470 O O   . HOH K 3 .   ? -75.561  10.955  84.672  1.00 20.55  ? 801 HOH A O   1 
HETATM 17471 O O   . HOH K 3 .   ? -69.589  -5.812  43.010  1.00 34.21  ? 802 HOH A O   1 
HETATM 17472 O O   . HOH K 3 .   ? -65.320  -14.227 50.871  1.00 22.53  ? 803 HOH A O   1 
HETATM 17473 O O   . HOH K 3 .   ? -62.754  -24.249 54.914  1.00 31.15  ? 804 HOH A O   1 
HETATM 17474 O O   . HOH K 3 .   ? -38.789  -20.191 58.196  1.00 36.48  ? 805 HOH A O   1 
HETATM 17475 O O   . HOH K 3 .   ? -81.788  -29.891 104.218 1.00 40.02  ? 806 HOH A O   1 
HETATM 17476 O O   . HOH K 3 .   ? -95.135  7.455   75.030  1.00 36.39  ? 807 HOH A O   1 
HETATM 17477 O O   . HOH K 3 .   ? -60.147  0.060   87.181  1.00 31.57  ? 808 HOH A O   1 
HETATM 17478 O O   . HOH L 3 .   ? -16.639  -43.258 81.719  1.00 39.80  ? 801 HOH B O   1 
HETATM 17479 O O   . HOH L 3 .   ? -8.782   -32.558 62.225  1.00 49.07  ? 802 HOH B O   1 
HETATM 17480 O O   . HOH L 3 .   ? -37.510  1.944   62.973  1.00 28.40  ? 803 HOH B O   1 
HETATM 17481 O O   . HOH L 3 .   ? -19.686  -23.653 103.603 1.00 46.80  ? 804 HOH B O   1 
HETATM 17482 O O   . HOH M 3 .   ? -81.918  -42.181 10.549  1.00 19.02  ? 801 HOH C O   1 
HETATM 17483 O O   . HOH M 3 .   ? -77.293  -41.136 16.632  1.00 35.50  ? 802 HOH C O   1 
HETATM 17484 O O   . HOH M 3 .   ? -75.083  -14.407 37.384  1.00 40.47  ? 803 HOH C O   1 
HETATM 17485 O O   . HOH M 3 .   ? -64.913  -8.661  39.327  1.00 38.74  ? 804 HOH C O   1 
HETATM 17486 O O   . HOH M 3 .   ? -61.305  2.923   29.680  1.00 41.39  ? 805 HOH C O   1 
HETATM 17487 O O   . HOH M 3 .   ? -79.004  -22.296 -10.836 1.00 41.46  ? 806 HOH C O   1 
HETATM 17488 O O   . HOH M 3 .   ? -67.435  -27.916 50.921  1.00 37.39  ? 807 HOH C O   1 
HETATM 17489 O O   . HOH N 3 .   ? -22.903  11.674  8.453   1.00 29.73  ? 801 HOH D O   1 
HETATM 17490 O O   . HOH N 3 .   ? -23.747  -17.436 7.844   1.00 30.60  ? 802 HOH D O   1 
HETATM 17491 O O   . HOH N 3 .   ? -55.429  -42.502 39.688  1.00 51.26  ? 803 HOH D O   1 
HETATM 17492 O O   . HOH N 3 .   ? -33.475  -13.967 42.320  1.00 19.86  ? 804 HOH D O   1 
HETATM 17493 O O   . HOH N 3 .   ? -25.184  -18.395 33.938  1.00 37.83  ? 805 HOH D O   1 
HETATM 17494 O O   . HOH N 3 .   ? -29.006  -6.166  49.943  1.00 34.19  ? 806 HOH D O   1 
HETATM 17495 O O   . HOH N 3 .   ? -31.010  -23.912 -7.259  1.00 40.18  ? 807 HOH D O   1 
HETATM 17496 O O   . HOH N 3 .   ? -38.548  0.919   5.935   1.00 34.13  ? 808 HOH D O   1 
HETATM 17497 O O   . HOH N 3 .   ? -36.874  8.671   11.681  1.00 35.12  ? 809 HOH D O   1 
HETATM 17498 O O   . HOH N 3 .   ? -28.536  -9.907  47.031  1.00 44.00  ? 810 HOH D O   1 
# 
